id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ajst-405	Man, Yunqi; Liu, Chengcheng	Development and Application of Suppositories in Modern Pharmaceutics	2022	3	.pdf	application/pdf	2791	115	40	Hollow Plugs With the development of suppositories, Tandou Shanfeng et al developed hollow suppositories (HTS) in 1984, whose outer layer is a shell made of matrix and hollow can be filled with drugs in various states such as solid, liquid and suspended States, HTS offers the possibility of rectal drug delivery for many drugs due to its rapid drug release, high bioavailability and wide application range compared with common suppositories. Gel Suppository Plugs Compared with common suppositories, the foreign body 42 sensation generated after the incorporation of suppositories into the body cavity can be avoided due to the fact that the gels have a special adhesive force to the biological mucosa, which can prolong the retention and release time of drugs to promote the absorption of drugs and improve the bioavailability of drugs.	cache/ajst-405.pdf	txt/ajst-405.txt