id	sid	tid	token	lemma	pos
ajst-18313	1	1	academic	academic	ADJ
ajst-18313	1	2	journal	journal	NOUN
ajst-18313	1	3	of	of	ADP
ajst-18313	1	4	science	science	NOUN
ajst-18313	1	5	and	and	CCONJ
ajst-18313	1	6	technology	technology	NOUN
ajst-18313	1	7	issn	issn	NOUN
ajst-18313	1	8	:	:	PUNCT
ajst-18313	1	9	2771	2771	NUM
ajst-18313	1	10	-	-	SYM
ajst-18313	1	11	3032	3032	NUM
ajst-18313	1	12	|	|	NOUN
ajst-18313	1	13	vol	vol	NOUN
ajst-18313	1	14	.	.	PROPN
ajst-18313	2	1	9	9	NUM
ajst-18313	2	2	,	,	PUNCT
ajst-18313	2	3	no	no	INTJ
ajst-18313	2	4	.	.	NOUN
ajst-18313	2	5	3	3	NUM
ajst-18313	2	6	,	,	PUNCT
ajst-18313	2	7	2024	2024	NUM
ajst-18313	2	8	9	9	NUM
ajst-18313	2	9	the	the	DET
ajst-18313	2	10	methods	method	NOUN
ajst-18313	2	11	and	and	CCONJ
ajst-18313	2	12	strategies	strategy	NOUN
ajst-18313	2	13	to	to	PART
ajst-18313	2	14	improve	improve	VERB
ajst-18313	2	15	the	the	DET
ajst-18313	2	16	stability	stability	NOUN
ajst-18313	2	17	of	of	ADP
ajst-18313	2	18	nano	nano	VERB
ajst-18313	2	19	antibody	antibody	NOUN
ajst-18313	2	20	zimeng	zimeng	NOUN
ajst-18313	2	21	wang	wang	PROPN
ajst-18313	2	22	jinan	jinan	PROPN
ajst-18313	2	23	foreign	foreign	PROPN
ajst-18313	2	24	language	language	PROPN
ajst-18313	2	25	school	school	NOUN
ajst-18313	2	26	,	,	PUNCT
ajst-18313	2	27	jinan	jinan	PROPN
ajst-18313	2	28	,	,	PUNCT
ajst-18313	2	29	china	china	PROPN
ajst-18313	2	30	abstract	abstract	PROPN
ajst-18313	2	31	:	:	PUNCT
ajst-18313	2	32	because	because	SCONJ
ajst-18313	2	33	of	of	ADP
ajst-18313	2	34	the	the	DET
ajst-18313	2	35	advantages	advantage	NOUN
ajst-18313	2	36	of	of	ADP
ajst-18313	2	37	simple	simple	ADJ
ajst-18313	2	38	structure	structure	NOUN
ajst-18313	2	39	,	,	PUNCT
ajst-18313	2	40	easy	easy	ADJ
ajst-18313	2	41	modification	modification	NOUN
ajst-18313	2	42	,	,	PUNCT
ajst-18313	2	43	low	low	ADJ
ajst-18313	2	44	immunogenicity	immunogenicity	NOUN
ajst-18313	2	45	,	,	PUNCT
ajst-18313	2	46	good	good	ADJ
ajst-18313	2	47	stability	stability	NOUN
ajst-18313	2	48	,	,	PUNCT
ajst-18313	2	49	strong	strong	ADJ
ajst-18313	2	50	specificity	specificity	NOUN
ajst-18313	2	51	and	and	CCONJ
ajst-18313	2	52	strong	strong	ADJ
ajst-18313	2	53	affinity	affinity	NOUN
ajst-18313	2	54	,	,	PUNCT
ajst-18313	2	55	nano	nano	NOUN
ajst-18313	2	56	-	-	PUNCT
ajst-18313	2	57	antibodies	antibody	NOUN
ajst-18313	2	58	have	have	VERB
ajst-18313	2	59	broad	broad	ADJ
ajst-18313	2	60	development	development	NOUN
ajst-18313	2	61	space	space	NOUN
ajst-18313	2	62	in	in	ADP
ajst-18313	2	63	clinical	clinical	ADJ
ajst-18313	2	64	practice	practice	NOUN
ajst-18313	2	65	.	.	PUNCT
ajst-18313	3	1	compared	compare	VERB
ajst-18313	3	2	with	with	ADP
ajst-18313	3	3	traditional	traditional	ADJ
ajst-18313	3	4	antibodies	antibody	NOUN
ajst-18313	3	5	,	,	PUNCT
ajst-18313	3	6	nano	nano	NOUN
ajst-18313	3	7	antibodies	antibody	NOUN
ajst-18313	3	8	are	be	AUX
ajst-18313	3	9	easier	easy	ADJ
ajst-18313	3	10	to	to	PART
ajst-18313	3	11	store	store	VERB
ajst-18313	3	12	and	and	CCONJ
ajst-18313	3	13	transport	transport	NOUN
ajst-18313	3	14	,	,	PUNCT
ajst-18313	3	15	and	and	CCONJ
ajst-18313	3	16	after	after	ADP
ajst-18313	3	17	denaturation	denaturation	NOUN
ajst-18313	3	18	in	in	ADP
ajst-18313	3	19	high	high	ADJ
ajst-18313	3	20	temperature	temperature	NOUN
ajst-18313	3	21	,	,	PUNCT
ajst-18313	3	22	chemical	chemical	NOUN
ajst-18313	3	23	,	,	PUNCT
ajst-18313	3	24	pressure	pressure	NOUN
ajst-18313	3	25	and	and	CCONJ
ajst-18313	3	26	other	other	ADJ
ajst-18313	3	27	environments	environment	NOUN
ajst-18313	3	28	,	,	PUNCT
ajst-18313	3	29	they	they	PRON
ajst-18313	3	30	can	can	AUX
ajst-18313	3	31	still	still	ADV
ajst-18313	3	32	be	be	AUX
ajst-18313	3	33	efficiently	efficiently	ADV
ajst-18313	3	34	recombined	recombine	VERB
ajst-18313	3	35	,	,	PUNCT
ajst-18313	3	36	thereby	thereby	ADV
ajst-18313	3	37	regaining	regain	VERB
ajst-18313	3	38	affinity	affinity	NOUN
ajst-18313	3	39	for	for	ADP
ajst-18313	3	40	antigens	antigen	NOUN
ajst-18313	3	41	.	.	PUNCT
ajst-18313	4	1	the	the	DET
ajst-18313	4	2	structure	structure	NOUN
ajst-18313	4	3	and	and	CCONJ
ajst-18313	4	4	stability	stability	NOUN
ajst-18313	4	5	of	of	ADP
ajst-18313	4	6	nano	nano	NOUN
ajst-18313	4	7	antibody	antibody	NOUN
ajst-18313	4	8	were	be	AUX
ajst-18313	4	9	studied	study	VERB
ajst-18313	4	10	.	.	PUNCT
ajst-18313	5	1	multiple	multiple	ADJ
ajst-18313	5	2	dna	dna	PROPN
ajst-18313	5	3	sequence	sequence	NOUN
ajst-18313	5	4	repair	repair	VERB
ajst-18313	5	5	with	with	ADP
ajst-18313	5	6	the	the	DET
ajst-18313	5	7	same	same	ADJ
ajst-18313	5	8	sequence	sequence	NOUN
ajst-18313	5	9	,	,	PUNCT
ajst-18313	5	10	easily	easily	ADV
ajst-18313	5	11	modified	modify	VERB
ajst-18313	5	12	amino	amino	NOUN
ajst-18313	5	13	acid	acid	NOUN
ajst-18313	5	14	replacement	replacement	NOUN
ajst-18313	5	15	,	,	PUNCT
ajst-18313	5	16	protein	protein	NOUN
ajst-18313	5	17	net	net	ADJ
ajst-18313	5	18	charge	charge	NOUN
ajst-18313	5	19	change	change	NOUN
ajst-18313	5	20	,	,	PUNCT
ajst-18313	5	21	unnatural	unnatural	ADJ
ajst-18313	5	22	disulfide	disulfide	NOUN
ajst-18313	5	23	bond	bond	NOUN
ajst-18313	5	24	introduction	introduction	NOUN
ajst-18313	5	25	and	and	CCONJ
ajst-18313	5	26	cdr	cdr	PROPN
ajst-18313	5	27	supervariable	supervariable	PROPN
ajst-18313	5	28	region	region	NOUN
ajst-18313	5	29	transfer	transfer	NOUN
ajst-18313	5	30	was	be	AUX
ajst-18313	5	31	used	use	VERB
ajst-18313	5	32	to	to	PART
ajst-18313	5	33	control	control	VERB
ajst-18313	5	34	the	the	DET
ajst-18313	5	35	stability	stability	NOUN
ajst-18313	5	36	of	of	ADP
ajst-18313	5	37	the	the	DET
ajst-18313	5	38	protein	protein	NOUN
ajst-18313	5	39	.	.	PUNCT
ajst-18313	6	1	the	the	DET
ajst-18313	6	2	implementation	implementation	NOUN
ajst-18313	6	3	of	of	ADP
ajst-18313	6	4	this	this	DET
ajst-18313	6	5	project	project	NOUN
ajst-18313	6	6	is	be	AUX
ajst-18313	6	7	expected	expect	VERB
ajst-18313	6	8	to	to	PART
ajst-18313	6	9	lay	lay	VERB
ajst-18313	6	10	a	a	DET
ajst-18313	6	11	foundation	foundation	NOUN
ajst-18313	6	12	for	for	ADP
ajst-18313	6	13	improving	improve	VERB
ajst-18313	6	14	its	its	PRON
ajst-18313	6	15	application	application	NOUN
ajst-18313	6	16	in	in	ADP
ajst-18313	6	17	the	the	DET
ajst-18313	6	18	fields	field	NOUN
ajst-18313	6	19	of	of	ADP
ajst-18313	6	20	drug	drug	NOUN
ajst-18313	6	21	therapy	therapy	NOUN
ajst-18313	6	22	,	,	PUNCT
ajst-18313	6	23	diagnosis	diagnosis	NOUN
ajst-18313	6	24	and	and	CCONJ
ajst-18313	6	25	biosensing	biosensing	NOUN
ajst-18313	6	26	.	.	PUNCT
ajst-18313	7	1	keywords	keyword	NOUN
ajst-18313	7	2	:	:	PUNCT
ajst-18313	7	3	nano	nano	NOUN
ajst-18313	7	4	-	-	PUNCT
ajst-18313	7	5	antibody	antibody	NOUN
ajst-18313	7	6	;	;	PUNCT
ajst-18313	7	7	stability	stability	NOUN
ajst-18313	7	8	;	;	PUNCT
ajst-18313	7	9	structure	structure	NOUN
ajst-18313	7	10	;	;	PUNCT
ajst-18313	7	11	sequence	sequence	NOUN
ajst-18313	7	12	.	.	PUNCT
ajst-18313	8	1	1	1	X
ajst-18313	8	2	.	.	X
ajst-18313	8	3	introduction	introduction	NOUN
ajst-18313	8	4	among	among	ADP
ajst-18313	8	5	them	they	PRON
ajst-18313	8	6	,	,	PUNCT
ajst-18313	8	7	stability	stability	NOUN
ajst-18313	8	8	is	be	AUX
ajst-18313	8	9	an	an	DET
ajst-18313	8	10	important	important	ADJ
ajst-18313	8	11	reason	reason	NOUN
ajst-18313	8	12	to	to	PART
ajst-18313	8	13	limit	limit	VERB
ajst-18313	8	14	the	the	DET
ajst-18313	8	15	wide	wide	ADJ
ajst-18313	8	16	use	use	NOUN
ajst-18313	8	17	of	of	ADP
ajst-18313	8	18	antibodies	antibody	NOUN
ajst-18313	8	19	.	.	PUNCT
ajst-18313	9	1	on	on	ADP
ajst-18313	9	2	the	the	DET
ajst-18313	9	3	one	one	NUM
ajst-18313	9	4	hand	hand	NOUN
ajst-18313	9	5	,	,	PUNCT
ajst-18313	9	6	in	in	ADP
ajst-18313	9	7	the	the	DET
ajst-18313	9	8	production	production	NOUN
ajst-18313	9	9	,	,	PUNCT
ajst-18313	9	10	transportation	transportation	NOUN
ajst-18313	9	11	,	,	PUNCT
ajst-18313	9	12	storage	storage	NOUN
ajst-18313	9	13	and	and	CCONJ
ajst-18313	9	14	use	use	NOUN
ajst-18313	9	15	,	,	PUNCT
ajst-18313	9	16	due	due	ADP
ajst-18313	9	17	to	to	ADP
ajst-18313	9	18	its	its	PRON
ajst-18313	9	19	own	own	ADJ
ajst-18313	9	20	instability	instability	NOUN
ajst-18313	9	21	,	,	PUNCT
ajst-18313	9	22	it	it	PRON
ajst-18313	9	23	is	be	AUX
ajst-18313	9	24	easy	easy	ADJ
ajst-18313	9	25	to	to	PART
ajst-18313	9	26	appear	appear	VERB
ajst-18313	9	27	in	in	ADP
ajst-18313	9	28	the	the	DET
ajst-18313	9	29	production	production	NOUN
ajst-18313	9	30	,	,	PUNCT
ajst-18313	9	31	transportation	transportation	NOUN
ajst-18313	9	32	,	,	PUNCT
ajst-18313	9	33	storage	storage	NOUN
ajst-18313	9	34	and	and	CCONJ
ajst-18313	9	35	use	use	NOUN
ajst-18313	9	36	of	of	ADP
ajst-18313	9	37	various	various	ADJ
ajst-18313	9	38	physical	physical	ADJ
ajst-18313	9	39	and	and	CCONJ
ajst-18313	9	40	chemical	chemical	NOUN
ajst-18313	9	41	properties	property	NOUN
ajst-18313	9	42	changes	change	NOUN
ajst-18313	9	43	;	;	PUNCT
ajst-18313	9	44	on	on	ADP
ajst-18313	9	45	the	the	DET
ajst-18313	9	46	other	other	ADJ
ajst-18313	9	47	hand	hand	NOUN
ajst-18313	9	48	,	,	PUNCT
ajst-18313	9	49	due	due	ADP
ajst-18313	9	50	to	to	ADP
ajst-18313	9	51	its	its	PRON
ajst-18313	9	52	own	own	ADJ
ajst-18313	9	53	unstable	unstable	ADJ
ajst-18313	9	54	aggregation	aggregation	NOUN
ajst-18313	9	55	,	,	PUNCT
ajst-18313	9	56	it	it	PRON
ajst-18313	9	57	may	may	AUX
ajst-18313	9	58	have	have	VERB
ajst-18313	9	59	a	a	DET
ajst-18313	9	60	greater	great	ADJ
ajst-18313	9	61	impact	impact	NOUN
ajst-18313	9	62	on	on	ADP
ajst-18313	9	63	the	the	DET
ajst-18313	9	64	yield	yield	NOUN
ajst-18313	9	65	,	,	PUNCT
ajst-18313	9	66	shelf	shelf	NOUN
ajst-18313	9	67	life	life	NOUN
ajst-18313	9	68	and	and	CCONJ
ajst-18313	9	69	immunogenicity	immunogenicity	NOUN
ajst-18313	9	70	of	of	ADP
ajst-18313	9	71	the	the	DET
ajst-18313	9	72	product	product	NOUN
ajst-18313	9	73	.	.	PUNCT
ajst-18313	10	1	therefore	therefore	ADV
ajst-18313	10	2	,	,	PUNCT
ajst-18313	10	3	the	the	DET
ajst-18313	10	4	stability	stability	NOUN
ajst-18313	10	5	of	of	ADP
ajst-18313	10	6	the	the	DET
ajst-18313	10	7	antibody	antibody	NOUN
ajst-18313	10	8	directly	directly	ADV
ajst-18313	10	9	affects	affect	VERB
ajst-18313	10	10	its	its	PRON
ajst-18313	10	11	biochemical	biochemical	ADJ
ajst-18313	10	12	evaluation	evaluation	NOUN
ajst-18313	10	13	,	,	PUNCT
ajst-18313	10	14	but	but	CCONJ
ajst-18313	10	15	also	also	ADV
ajst-18313	10	16	relates	relate	VERB
ajst-18313	10	17	to	to	ADP
ajst-18313	10	18	its	its	PRON
ajst-18313	10	19	purification	purification	NOUN
ajst-18313	10	20	,	,	PUNCT
ajst-18313	10	21	storage	storage	NOUN
ajst-18313	10	22	,	,	PUNCT
ajst-18313	10	23	formulation	formulation	NOUN
ajst-18313	10	24	design	design	NOUN
ajst-18313	10	25	and	and	CCONJ
ajst-18313	10	26	manufacture	manufacture	VERB
ajst-18313	10	27	[	[	X
ajst-18313	10	28	1	1	NUM
ajst-18313	10	29	]	]	PUNCT
ajst-18313	10	30	.	.	PUNCT
ajst-18313	11	1	among	among	ADP
ajst-18313	11	2	them	they	PRON
ajst-18313	11	3	,	,	PUNCT
ajst-18313	11	4	nano	nano	NOUN
ajst-18313	11	5	antibodies	antibodie	VERB
ajst-18313	11	6	are	be	AUX
ajst-18313	11	7	chemical	chemical	NOUN
ajst-18313	11	8	denaturation	denaturation	NOUN
ajst-18313	11	9	resistance	resistance	NOUN
ajst-18313	11	10	,	,	PUNCT
ajst-18313	11	11	which	which	PRON
ajst-18313	11	12	are	be	AUX
ajst-18313	11	13	expected	expect	VERB
ajst-18313	11	14	to	to	PART
ajst-18313	11	15	solve	solve	VERB
ajst-18313	11	16	the	the	DET
ajst-18313	11	17	difficult	difficult	ADJ
ajst-18313	11	18	problems	problem	NOUN
ajst-18313	11	19	such	such	ADJ
ajst-18313	11	20	as	as	ADP
ajst-18313	11	21	easy	easy	ADJ
ajst-18313	11	22	aggregation	aggregation	NOUN
ajst-18313	11	23	and	and	CCONJ
ajst-18313	11	24	decomposition	decomposition	NOUN
ajst-18313	11	25	of	of	ADP
ajst-18313	11	26	conventional	conventional	ADJ
ajst-18313	11	27	monoclonal	monoclonal	NOUN
ajst-18313	11	28	antibodies	antibodie	VERB
ajst-18313	11	29	.	.	PUNCT
ajst-18313	12	1	although	although	SCONJ
ajst-18313	12	2	nano	nano	NOUN
ajst-18313	12	3	antibodies	antibodie	VERB
ajst-18313	12	4	are	be	AUX
ajst-18313	12	5	better	well	ADJ
ajst-18313	12	6	than	than	ADP
ajst-18313	12	7	conventional	conventional	ADJ
ajst-18313	12	8	antibodies	antibody	NOUN
ajst-18313	12	9	in	in	ADP
ajst-18313	12	10	terms	term	NOUN
ajst-18313	12	11	of	of	ADP
ajst-18313	12	12	stability	stability	NOUN
ajst-18313	12	13	,	,	PUNCT
ajst-18313	12	14	their	their	PRON
ajst-18313	12	15	stability	stability	NOUN
ajst-18313	12	16	is	be	AUX
ajst-18313	12	17	very	very	ADV
ajst-18313	12	18	different	different	ADJ
ajst-18313	12	19	due	due	ADP
ajst-18313	12	20	to	to	ADP
ajst-18313	12	21	their	their	PRON
ajst-18313	12	22	unique	unique	ADJ
ajst-18313	12	23	spatial	spatial	ADJ
ajst-18313	12	24	structure	structure	NOUN
ajst-18313	12	25	.	.	PUNCT
ajst-18313	13	1	in	in	ADP
ajst-18313	13	2	recent	recent	ADJ
ajst-18313	13	3	years	year	NOUN
ajst-18313	13	4	,	,	PUNCT
ajst-18313	13	5	many	many	ADJ
ajst-18313	13	6	scholars	scholar	NOUN
ajst-18313	13	7	have	have	AUX
ajst-18313	13	8	enhanced	enhance	VERB
ajst-18313	13	9	their	their	PRON
ajst-18313	13	10	stability	stability	NOUN
ajst-18313	13	11	by	by	ADP
ajst-18313	13	12	optimizing	optimize	VERB
ajst-18313	13	13	their	their	PRON
ajst-18313	13	14	common	common	ADJ
ajst-18313	13	15	sequences	sequence	NOUN
ajst-18313	13	16	and	and	CCONJ
ajst-18313	13	17	discovered	discover	VERB
ajst-18313	13	18	common	common	ADJ
ajst-18313	13	19	structural	structural	ADJ
ajst-18313	13	20	features	feature	NOUN
ajst-18313	13	21	that	that	PRON
ajst-18313	13	22	inhibit	inhibit	VERB
ajst-18313	13	23	their	their	PRON
ajst-18313	13	24	aggregation	aggregation	NOUN
ajst-18313	13	25	.	.	PUNCT
ajst-18313	14	1	in	in	ADP
ajst-18313	14	2	this	this	DET
ajst-18313	14	3	paper	paper	NOUN
ajst-18313	14	4	,	,	PUNCT
ajst-18313	14	5	the	the	DET
ajst-18313	14	6	stability	stability	NOUN
ajst-18313	14	7	of	of	ADP
ajst-18313	14	8	nano	nano	NOUN
ajst-18313	14	9	-	-	PUNCT
ajst-18313	14	10	antibody	antibody	NOUN
ajst-18313	14	11	was	be	AUX
ajst-18313	14	12	studied	study	VERB
ajst-18313	14	13	and	and	CCONJ
ajst-18313	14	14	its	its	PRON
ajst-18313	14	15	stability	stability	NOUN
ajst-18313	14	16	in	in	ADP
ajst-18313	14	17	extreme	extreme	ADJ
ajst-18313	14	18	environment	environment	NOUN
ajst-18313	14	19	such	such	ADJ
ajst-18313	14	20	as	as	ADP
ajst-18313	14	21	high	high	ADJ
ajst-18313	14	22	temperature	temperature	NOUN
ajst-18313	14	23	and	and	CCONJ
ajst-18313	14	24	organic	organic	ADJ
ajst-18313	14	25	solvent	solvent	NOUN
ajst-18313	14	26	was	be	AUX
ajst-18313	14	27	elucidated	elucidate	VERB
ajst-18313	15	1	[	[	PUNCT
ajst-18313	15	2	2	2	NUM
ajst-18313	15	3	]	]	PUNCT
ajst-18313	15	4	.	.	PUNCT
ajst-18313	16	1	the	the	DET
ajst-18313	16	2	high	high	ADJ
ajst-18313	16	3	-	-	PUNCT
ajst-18313	16	4	charge	charge	NOUN
ajst-18313	16	5	surfaces	surface	NOUN
ajst-18313	16	6	,	,	PUNCT
ajst-18313	16	7	disulfide	disulfide	NOUN
ajst-18313	16	8	bonds	bond	NOUN
ajst-18313	16	9	that	that	PRON
ajst-18313	16	10	restrict	restrict	VERB
ajst-18313	16	11	conformation	conformation	NOUN
ajst-18313	16	12	migration	migration	NOUN
ajst-18313	16	13	,	,	PUNCT
ajst-18313	16	14	more	more	ADV
ajst-18313	16	15	hydrophilic	hydrophilic	ADJ
ajst-18313	16	16	amino	amino	NOUN
ajst-18313	16	17	acid	acid	NOUN
ajst-18313	16	18	substitution	substitution	NOUN
ajst-18313	16	19	skeleton	skeleton	NOUN
ajst-18313	16	20	regions	region	NOUN
ajst-18313	16	21	,	,	PUNCT
ajst-18313	16	22	conservative	conservative	ADJ
ajst-18313	16	23	hydrophobic	hydrophobic	NOUN
ajst-18313	16	24	regions	region	NOUN
ajst-18313	16	25	and	and	CCONJ
ajst-18313	16	26	strongly	strongly	ADV
ajst-18313	16	27	interacting	interact	VERB
ajst-18313	16	28	functional	functional	ADJ
ajst-18313	16	29	regions	region	NOUN
ajst-18313	16	30	were	be	AUX
ajst-18313	16	31	analyzed	analyze	VERB
ajst-18313	16	32	[	[	X
ajst-18313	16	33	3	3	NUM
ajst-18313	16	34	]	]	PUNCT
ajst-18313	16	35	.	.	PUNCT
ajst-18313	17	1	the	the	DET
ajst-18313	17	2	methods	method	NOUN
ajst-18313	17	3	of	of	ADP
ajst-18313	17	4	dna	dna	PROPN
ajst-18313	17	5	sequence	sequence	NOUN
ajst-18313	17	6	repair	repair	NOUN
ajst-18313	17	7	,	,	PUNCT
ajst-18313	17	8	easy	easy	ADJ
ajst-18313	17	9	amino	amino	NOUN
ajst-18313	17	10	acid	acid	NOUN
ajst-18313	17	11	replacement	replacement	NOUN
ajst-18313	17	12	,	,	PUNCT
ajst-18313	17	13	protein	protein	NOUN
ajst-18313	17	14	net	net	ADJ
ajst-18313	17	15	charge	charge	NOUN
ajst-18313	17	16	change	change	NOUN
ajst-18313	17	17	,	,	PUNCT
ajst-18313	17	18	unnatural	unnatural	ADJ
ajst-18313	17	19	disulfide	disulfide	NOUN
ajst-18313	17	20	bond	bond	NOUN
ajst-18313	17	21	introduction	introduction	NOUN
ajst-18313	17	22	and	and	CCONJ
ajst-18313	17	23	functional	functional	ADJ
ajst-18313	17	24	complementary	complementary	ADJ
ajst-18313	17	25	region	region	NOUN
ajst-18313	17	26	(	(	PUNCT
ajst-18313	17	27	cdrs	cdrs	PROPN
ajst-18313	17	28	)	)	PUNCT
ajst-18313	17	29	modification	modification	NOUN
ajst-18313	17	30	were	be	AUX
ajst-18313	17	31	discussed	discuss	VERB
ajst-18313	17	32	.	.	PUNCT
ajst-18313	18	1	2	2	X
ajst-18313	18	2	.	.	X
ajst-18313	18	3	nanometer	nanometer	NOUN
ajst-18313	18	4	antibody	antibody	NOUN
ajst-18313	18	5	structure	structure	NOUN
ajst-18313	18	6	the	the	DET
ajst-18313	18	7	novel	novel	ADJ
ajst-18313	18	8	antibody	antibody	NOUN
ajst-18313	18	9	resembles	resemble	VERB
ajst-18313	18	10	a	a	DET
ajst-18313	18	11	conventional	conventional	ADJ
ajst-18313	18	12	antibody	antibody	NOUN
ajst-18313	18	13	variable	variable	ADJ
ajst-18313	18	14	region	region	NOUN
ajst-18313	18	15	(	(	PUNCT
ajst-18313	18	16	vh	vh	PROPN
ajst-18313	18	17	)	)	PUNCT
ajst-18313	18	18	with	with	ADP
ajst-18313	18	19	a	a	DET
ajst-18313	18	20	skeleton	skeleton	NOUN
ajst-18313	18	21	of	of	ADP
ajst-18313	18	22	nine	nine	NUM
ajst-18313	18	23	beta	beta	NOUN
ajst-18313	18	24	-	-	PUNCT
ajst-18313	18	25	folded	fold	VERB
ajst-18313	18	26	sheets	sheet	NOUN
ajst-18313	18	27	in	in	ADP
ajst-18313	18	28	opposite	opposite	ADJ
ajst-18313	18	29	directions	direction	NOUN
ajst-18313	18	30	connected	connect	VERB
ajst-18313	18	31	by	by	ADP
ajst-18313	18	32	disulphide	disulphide	ADJ
ajst-18313	18	33	bonds	bond	NOUN
ajst-18313	18	34	or	or	CCONJ
ajst-18313	18	35	interchains	interchain	NOUN
ajst-18313	18	36	(	(	PUNCT
ajst-18313	18	37	figure	figure	NOUN
ajst-18313	18	38	1	1	NUM
ajst-18313	18	39	cited	cite	VERB
ajst-18313	18	40	in	in	ADP
ajst-18313	18	41	biomolecules	biomolecule	NOUN
ajst-18313	18	42	2021	2021	NUM
ajst-18313	18	43	,	,	PUNCT
ajst-18313	18	44	11(5	11(5	NUM
ajst-18313	18	45	)	)	PUNCT
ajst-18313	18	46	,	,	PUNCT
ajst-18313	18	47	637	637	NUM
ajst-18313	18	48	)	)	PUNCT
ajst-18313	18	49	.	.	PUNCT
ajst-18313	19	1	the	the	DET
ajst-18313	19	2	system	system	NOUN
ajst-18313	19	3	consists	consist	VERB
ajst-18313	19	4	of	of	ADP
ajst-18313	19	5	three	three	NUM
ajst-18313	19	6	cdrs	cdr	NOUN
ajst-18313	19	7	connecting	connect	VERB
ajst-18313	19	8	bc	bc	PROPN
ajst-18313	19	9	,	,	PUNCT
ajst-18313	19	10	de	de	ADP
ajst-18313	19	11	and	and	CCONJ
ajst-18313	19	12	hi	hi	ADJ
ajst-18313	19	13	terminals	terminal	NOUN
ajst-18313	19	14	respectively	respectively	ADV
ajst-18313	19	15	,	,	PUNCT
ajst-18313	19	16	and	and	CCONJ
ajst-18313	19	17	a	a	DET
ajst-18313	19	18	continuous	continuous	ADJ
ajst-18313	19	19	surface	surface	NOUN
ajst-18313	19	20	matching	match	VERB
ajst-18313	19	21	the	the	DET
ajst-18313	19	22	epitopes	epitope	NOUN
ajst-18313	19	23	is	be	AUX
ajst-18313	19	24	formed	form	VERB
ajst-18313	19	25	through	through	ADP
ajst-18313	19	26	the	the	DET
ajst-18313	19	27	n	n	CCONJ
ajst-18313	19	28	-	-	PUNCT
ajst-18313	19	29	terminal	terminal	NOUN
ajst-18313	19	30	.	.	PUNCT
ajst-18313	20	1	the	the	DET
ajst-18313	20	2	skeleton	skeleton	NOUN
ajst-18313	20	3	region	region	NOUN
ajst-18313	20	4	(	(	PUNCT
ajst-18313	20	5	fr	fr	NOUN
ajst-18313	20	6	)	)	PUNCT
ajst-18313	20	7	between	between	ADP
ajst-18313	20	8	cdrs	cdrs	PROPN
ajst-18313	20	9	is	be	AUX
ajst-18313	20	10	a	a	DET
ajst-18313	20	11	highly	highly	ADV
ajst-18313	20	12	conserved	conserved	ADJ
ajst-18313	20	13	domain	domain	NOUN
ajst-18313	20	14	.	.	PUNCT
ajst-18313	21	1	most	most	ADJ
ajst-18313	21	2	of	of	ADP
ajst-18313	21	3	the	the	DET
ajst-18313	21	4	nano	nano	NOUN
ajst-18313	21	5	-	-	PUNCT
ajst-18313	21	6	antibody	antibody	NOUN
ajst-18313	21	7	molecules	molecule	NOUN
ajst-18313	21	8	have	have	VERB
ajst-18313	21	9	a	a	DET
ajst-18313	21	10	double	double	ADJ
ajst-18313	21	11	disulfide	disulfide	NOUN
ajst-18313	21	12	bond	bond	NOUN
ajst-18313	21	13	connecting	connect	VERB
ajst-18313	21	14	fr1	fr1	PROPN
ajst-18313	21	15	(	(	PUNCT
ajst-18313	21	16	c23	c23	PROPN
ajst-18313	21	17	)	)	PUNCT
ajst-18313	21	18	and	and	CCONJ
ajst-18313	21	19	fr3	fr3	PROPN
ajst-18313	21	20	(	(	PUNCT
ajst-18313	21	21	c104	c104	PROPN
ajst-18313	21	22	)	)	PUNCT
ajst-18313	21	23	,	,	PUNCT
ajst-18313	21	24	and	and	CCONJ
ajst-18313	21	25	the	the	DET
ajst-18313	21	26	two	two	NUM
ajst-18313	21	27	betas	beta	NOUN
ajst-18313	21	28	are	be	AUX
ajst-18313	21	29	connected	connect	VERB
ajst-18313	21	30	by	by	ADP
ajst-18313	21	31	covalent	covalent	NOUN
ajst-18313	21	32	bond	bond	NOUN
ajst-18313	21	33	,	,	PUNCT
ajst-18313	21	34	thus	thus	ADV
ajst-18313	21	35	improving	improve	VERB
ajst-18313	21	36	the	the	DET
ajst-18313	21	37	structural	structural	ADJ
ajst-18313	21	38	stability	stability	NOUN
ajst-18313	21	39	of	of	ADP
ajst-18313	21	40	the	the	DET
ajst-18313	21	41	molecule	molecule	NOUN
ajst-18313	22	1	[	[	X
ajst-18313	22	2	4	4	NUM
ajst-18313	22	3	]	]	PUNCT
ajst-18313	22	4	.	.	PUNCT
ajst-18313	23	1	conventional	conventional	ADJ
ajst-18313	23	2	vh	vh	PROPN
ajst-18313	23	3	and	and	CCONJ
ajst-18313	23	4	vl	vl	PROPN
ajst-18313	23	5	are	be	AUX
ajst-18313	23	6	formed	form	VERB
ajst-18313	23	7	by	by	ADP
ajst-18313	23	8	hydrophobic	hydrophobic	NOUN
ajst-18313	23	9	interaction	interaction	NOUN
ajst-18313	23	10	.	.	PUNCT
ajst-18313	24	1	however	however	ADV
ajst-18313	24	2	,	,	PUNCT
ajst-18313	24	3	because	because	SCONJ
ajst-18313	24	4	it	it	PRON
ajst-18313	24	5	contains	contain	VERB
ajst-18313	24	6	only	only	ADV
ajst-18313	24	7	three	three	NUM
ajst-18313	24	8	variable	variable	ADJ
ajst-18313	24	9	regions	region	NOUN
ajst-18313	24	10	,	,	PUNCT
ajst-18313	24	11	it	it	PRON
ajst-18313	24	12	still	still	ADV
ajst-18313	24	13	maintains	maintain	VERB
ajst-18313	24	14	good	good	ADJ
ajst-18313	24	15	biocompatibility	biocompatibility	NOUN
ajst-18313	24	16	with	with	ADP
ajst-18313	24	17	a	a	DET
ajst-18313	24	18	reduced	reduce	VERB
ajst-18313	24	19	surface	surface	NOUN
ajst-18313	24	20	area	area	NOUN
ajst-18313	24	21	.	.	PUNCT
ajst-18313	25	1	this	this	DET
ajst-18313	25	2	project	project	NOUN
ajst-18313	25	3	intends	intend	VERB
ajst-18313	25	4	to	to	PART
ajst-18313	25	5	design	design	VERB
ajst-18313	25	6	and	and	CCONJ
ajst-18313	25	7	synthesize	synthesize	VERB
ajst-18313	25	8	a	a	DET
ajst-18313	25	9	series	series	NOUN
ajst-18313	25	10	of	of	ADP
ajst-18313	25	11	novel	novel	NOUN
ajst-18313	25	12	polypeptide	polypeptide	ADJ
ajst-18313	25	13	molecules	molecule	NOUN
ajst-18313	25	14	with	with	ADP
ajst-18313	25	15	good	good	ADJ
ajst-18313	25	16	biocompatibility	biocompatibility	NOUN
ajst-18313	25	17	by	by	ADP
ajst-18313	25	18	introducing	introduce	VERB
ajst-18313	25	19	a	a	DET
ajst-18313	25	20	number	number	NOUN
ajst-18313	25	21	of	of	ADP
ajst-18313	25	22	hydrophilic	hydrophilic	ADJ
ajst-18313	25	23	amino	amino	NOUN
ajst-18313	25	24	acids	acid	NOUN
ajst-18313	25	25	to	to	PART
ajst-18313	25	26	replace	replace	VERB
ajst-18313	25	27	the	the	DET
ajst-18313	25	28	original	original	ADJ
ajst-18313	25	29	aliphatic	aliphatic	ADJ
ajst-18313	25	30	residues	residue	NOUN
ajst-18313	25	31	on	on	ADP
ajst-18313	25	32	the	the	DET
ajst-18313	25	33	binding	bind	VERB
ajst-18313	25	34	interface	interface	NOUN
ajst-18313	25	35	with	with	ADP
ajst-18313	25	36	ch1	ch1	PROPN
ajst-18313	25	37	and	and	CCONJ
ajst-18313	25	38	vl	vl	PROPN
ajst-18313	25	39	.	.	PUNCT
ajst-18313	26	1	this	this	PRON
ajst-18313	26	2	makes	make	VERB
ajst-18313	26	3	it	it	PRON
ajst-18313	26	4	have	have	VERB
ajst-18313	26	5	high	high	ADJ
ajst-18313	26	6	stability	stability	NOUN
ajst-18313	26	7	,	,	PUNCT
ajst-18313	26	8	and	and	CCONJ
ajst-18313	26	9	has	have	VERB
ajst-18313	26	10	a	a	DET
ajst-18313	26	11	strong	strong	ADJ
ajst-18313	26	12	stretchable	stretchable	ADJ
ajst-18313	26	13	twisted	twisted	ADJ
ajst-18313	26	14	cdr3	cdr3	ADJ
ajst-18313	26	15	structure	structure	NOUN
ajst-18313	26	16	,	,	PUNCT
ajst-18313	26	17	so	so	SCONJ
ajst-18313	26	18	that	that	SCONJ
ajst-18313	26	19	it	it	PRON
ajst-18313	26	20	is	be	AUX
ajst-18313	26	21	not	not	PART
ajst-18313	26	22	in	in	ADP
ajst-18313	26	23	direct	direct	ADJ
ajst-18313	26	24	contact	contact	NOUN
ajst-18313	26	25	with	with	ADP
ajst-18313	26	26	external	external	ADJ
ajst-18313	26	27	water	water	NOUN
ajst-18313	26	28	,	,	PUNCT
ajst-18313	26	29	and	and	CCONJ
ajst-18313	26	30	can	can	AUX
ajst-18313	26	31	effectively	effectively	ADV
ajst-18313	26	32	inhibit	inhibit	VERB
ajst-18313	26	33	dimerization	dimerization	NOUN
ajst-18313	26	34	.	.	PUNCT
ajst-18313	27	1	in	in	ADP
ajst-18313	27	2	addition	addition	NOUN
ajst-18313	27	3	,	,	PUNCT
ajst-18313	27	4	the	the	DET
ajst-18313	27	5	hydrophilic	hydrophilic	ADJ
ajst-18313	27	6	core	core	NOUN
ajst-18313	27	7	of	of	ADP
ajst-18313	27	8	cdr3	cdr3	PROPN
ajst-18313	27	9	can	can	AUX
ajst-18313	27	10	make	make	VERB
ajst-18313	27	11	it	it	PRON
ajst-18313	27	12	have	have	VERB
ajst-18313	27	13	a	a	DET
ajst-18313	27	14	larger	large	ADJ
ajst-18313	27	15	length	length	NOUN
ajst-18313	27	16	of	of	ADP
ajst-18313	27	17	cdr1	cdr1	PROPN
ajst-18313	27	18	and	and	CCONJ
ajst-18313	27	19	cdr3	cdr3	ADJ
ajst-18313	27	20	,	,	PUNCT
ajst-18313	27	21	so	so	SCONJ
ajst-18313	27	22	that	that	SCONJ
ajst-18313	27	23	it	it	PRON
ajst-18313	27	24	has	have	VERB
ajst-18313	27	25	a	a	DET
ajst-18313	27	26	stronger	strong	ADJ
ajst-18313	27	27	spatial	spatial	ADJ
ajst-18313	27	28	configuration	configuration	NOUN
ajst-18313	27	29	,	,	PUNCT
ajst-18313	27	30	which	which	PRON
ajst-18313	27	31	can	can	AUX
ajst-18313	27	32	effectively	effectively	ADV
ajst-18313	27	33	produce	produce	VERB
ajst-18313	27	34	a	a	DET
ajst-18313	27	35	strong	strong	ADJ
ajst-18313	27	36	spatial	spatial	ADJ
ajst-18313	27	37	complementarity	complementarity	NOUN
ajst-18313	27	38	with	with	ADP
ajst-18313	27	39	the	the	DET
ajst-18313	27	40	corresponding	correspond	VERB
ajst-18313	27	41	antigen	antigen	ADJ
ajst-18313	27	42	molecules	molecule	NOUN
ajst-18313	27	43	,	,	PUNCT
ajst-18313	27	44	and	and	CCONJ
ajst-18313	27	45	partially	partially	ADV
ajst-18313	27	46	compensate	compensate	VERB
ajst-18313	27	47	for	for	ADP
ajst-18313	27	48	the	the	DET
ajst-18313	27	49	weakening	weakening	NOUN
ajst-18313	27	50	of	of	ADP
ajst-18313	27	51	binding	bind	VERB
ajst-18313	27	52	force	force	NOUN
ajst-18313	27	53	caused	cause	VERB
ajst-18313	27	54	by	by	ADP
ajst-18313	27	55	the	the	DET
ajst-18313	27	56	loss	loss	NOUN
ajst-18313	27	57	of	of	ADP
ajst-18313	27	58	light	light	ADJ
ajst-18313	27	59	chain	chain	NOUN
ajst-18313	27	60	and	and	CCONJ
ajst-18313	27	61	the	the	DET
ajst-18313	27	62	sequence	sequence	NOUN
ajst-18313	27	63	variation	variation	NOUN
ajst-18313	27	64	caused	cause	VERB
ajst-18313	27	65	by	by	ADP
ajst-18313	27	66	the	the	DET
ajst-18313	27	67	small	small	ADJ
ajst-18313	27	68	volume	volume	NOUN
ajst-18313	27	69	.	.	PUNCT
ajst-18313	28	1	3	3	X
ajst-18313	28	2	.	.	X
ajst-18313	28	3	stability	stability	NOUN
ajst-18313	28	4	characterization	characterization	NOUN
ajst-18313	28	5	in	in	ADP
ajst-18313	28	6	order	order	NOUN
ajst-18313	28	7	to	to	PART
ajst-18313	28	8	achieve	achieve	VERB
ajst-18313	28	9	the	the	DET
ajst-18313	28	10	desired	desire	VERB
ajst-18313	28	11	effect	effect	NOUN
ajst-18313	28	12	and	and	CCONJ
ajst-18313	28	13	shelf	shelf	NOUN
ajst-18313	28	14	life	life	NOUN
ajst-18313	28	15	,	,	PUNCT
ajst-18313	28	16	its	its	PRON
ajst-18313	28	17	physical	physical	ADJ
ajst-18313	28	18	and	and	CCONJ
ajst-18313	28	19	chemical	chemical	NOUN
ajst-18313	28	20	properties	property	NOUN
ajst-18313	28	21	must	must	AUX
ajst-18313	28	22	be	be	AUX
ajst-18313	28	23	fully	fully	ADV
ajst-18313	28	24	studied	study	VERB
ajst-18313	28	25	.	.	PUNCT
ajst-18313	29	1	in	in	ADP
ajst-18313	29	2	the	the	DET
ajst-18313	29	3	process	process	NOUN
ajst-18313	29	4	of	of	ADP
ajst-18313	29	5	antibody	antibody	NOUN
ajst-18313	29	6	development	development	NOUN
ajst-18313	29	7	and	and	CCONJ
ajst-18313	29	8	application	application	NOUN
ajst-18313	29	9	,	,	PUNCT
ajst-18313	29	10	due	due	ADP
ajst-18313	29	11	to	to	ADP
ajst-18313	29	12	the	the	DET
ajst-18313	29	13	influence	influence	NOUN
ajst-18313	29	14	of	of	ADP
ajst-18313	29	15	temperature	temperature	NOUN
ajst-18313	29	16	,	,	PUNCT
ajst-18313	29	17	solvent	solvent	NOUN
ajst-18313	29	18	,	,	PUNCT
ajst-18313	29	19	pressure	pressure	NOUN
ajst-18313	29	20	,	,	PUNCT
ajst-18313	29	21	chemical	chemical	NOUN
ajst-18313	29	22	reagents	reagent	NOUN
ajst-18313	29	23	,	,	PUNCT
ajst-18313	29	24	acid	acid	NOUN
ajst-18313	29	25	-	-	PUNCT
ajst-18313	29	26	base	base	NOUN
ajst-18313	29	27	environment	environment	NOUN
ajst-18313	29	28	and	and	CCONJ
ajst-18313	29	29	protease	protease	NOUN
ajst-18313	29	30	,	,	PUNCT
ajst-18313	29	31	people	people	NOUN
ajst-18313	29	32	can	can	AUX
ajst-18313	29	33	evaluate	evaluate	VERB
ajst-18313	29	34	it	it	PRON
ajst-18313	29	35	according	accord	VERB
ajst-18313	29	36	to	to	ADP
ajst-18313	29	37	different	different	ADJ
ajst-18313	29	38	effects	effect	NOUN
ajst-18313	29	39	.	.	PUNCT
ajst-18313	30	1	10	10	NUM
ajst-18313	30	2	figure	figure	NOUN
ajst-18313	30	3	1	1	NUM
ajst-18313	30	4	.	.	PUNCT
ajst-18313	31	1	structure	structure	NOUN
ajst-18313	31	2	of	of	ADP
ajst-18313	31	3	nanoantibody	nanoantibody	NOUN
ajst-18313	31	4	3.1	3.1	NUM
ajst-18313	31	5	.	.	PUNCT
ajst-18313	32	1	heat	heat	NOUN
ajst-18313	32	2	resistance	resistance	NOUN
ajst-18313	32	3	as	as	ADP
ajst-18313	32	4	an	an	DET
ajst-18313	32	5	important	important	ADJ
ajst-18313	32	6	bioactive	bioactive	ADJ
ajst-18313	32	7	substance	substance	NOUN
ajst-18313	32	8	,	,	PUNCT
ajst-18313	32	9	it	it	PRON
ajst-18313	32	10	has	have	VERB
ajst-18313	32	11	good	good	ADJ
ajst-18313	32	12	thermal	thermal	ADJ
ajst-18313	32	13	stability	stability	NOUN
ajst-18313	32	14	and	and	CCONJ
ajst-18313	32	15	good	good	ADJ
ajst-18313	32	16	thermal	thermal	ADJ
ajst-18313	32	17	expansion	expansion	NOUN
ajst-18313	32	18	performance	performance	NOUN
ajst-18313	32	19	.	.	PUNCT
ajst-18313	33	1	some	some	DET
ajst-18313	33	2	nanoantibodies	nanoantibodie	NOUN
ajst-18313	33	3	are	be	AUX
ajst-18313	33	4	able	able	ADJ
ajst-18313	33	5	to	to	PART
ajst-18313	33	6	be	be	AUX
ajst-18313	33	7	cultured	cultured	ADJ
ajst-18313	33	8	at	at	ADP
ajst-18313	33	9	-20	-20	NUM
ajst-18313	33	10	°	°	NOUN
ajst-18313	34	1	c	c	X
ajst-18313	34	2	,	,	PUNCT
ajst-18313	34	3	4	4	NUM
ajst-18313	34	4	°	°	NUM
ajst-18313	34	5	c	c	NOUN
ajst-18313	34	6	or	or	CCONJ
ajst-18313	34	7	3	3	NUM
ajst-18313	34	8	°	°	X
ajst-18313	34	9	c	c	NOUN
ajst-18313	34	10	for	for	ADP
ajst-18313	34	11	several	several	ADJ
ajst-18313	34	12	years	year	NOUN
ajst-18313	34	13	without	without	ADP
ajst-18313	34	14	losing	lose	VERB
ajst-18313	34	15	their	their	PRON
ajst-18313	34	16	ability	ability	NOUN
ajst-18313	34	17	to	to	PART
ajst-18313	34	18	bind	bind	VERB
ajst-18313	34	19	to	to	ADP
ajst-18313	34	20	the	the	DET
ajst-18313	34	21	antigen	antigen	NOUN
ajst-18313	34	22	and	and	CCONJ
ajst-18313	34	23	can	can	AUX
ajst-18313	34	24	therefore	therefore	ADV
ajst-18313	34	25	be	be	AUX
ajst-18313	34	26	stored	store	VERB
ajst-18313	34	27	,	,	PUNCT
ajst-18313	34	28	stored	store	VERB
ajst-18313	34	29	and	and	CCONJ
ajst-18313	34	30	used	use	VERB
ajst-18313	34	31	at	at	ADP
ajst-18313	34	32	room	room	NOUN
ajst-18313	34	33	temperature	temperature	NOUN
ajst-18313	34	34	.	.	PUNCT
ajst-18313	35	1	with	with	ADP
ajst-18313	35	2	the	the	DET
ajst-18313	35	3	increase	increase	NOUN
ajst-18313	35	4	of	of	ADP
ajst-18313	35	5	temperature	temperature	NOUN
ajst-18313	35	6	,	,	PUNCT
ajst-18313	35	7	the	the	DET
ajst-18313	35	8	folding	fold	VERB
ajst-18313	35	9	ability	ability	NOUN
ajst-18313	35	10	of	of	ADP
ajst-18313	35	11	antibody	antibody	NOUN
ajst-18313	35	12	becomes	become	VERB
ajst-18313	35	13	stronger	strong	ADJ
ajst-18313	35	14	and	and	CCONJ
ajst-18313	35	15	stronger	strong	ADJ
ajst-18313	35	16	,	,	PUNCT
ajst-18313	35	17	and	and	CCONJ
ajst-18313	35	18	the	the	DET
ajst-18313	35	19	folding	fold	VERB
ajst-18313	35	20	temperature	temperature	NOUN
ajst-18313	35	21	is	be	AUX
ajst-18313	35	22	usually	usually	ADV
ajst-18313	35	23	used	use	VERB
ajst-18313	35	24	to	to	PART
ajst-18313	35	25	predict	predict	VERB
ajst-18313	35	26	the	the	DET
ajst-18313	35	27	folding	fold	VERB
ajst-18313	35	28	trend	trend	NOUN
ajst-18313	35	29	.	.	PUNCT
ajst-18313	36	1	the	the	DET
ajst-18313	36	2	melting	melting	NOUN
ajst-18313	36	3	point	point	NOUN
ajst-18313	36	4	of	of	ADP
ajst-18313	36	5	the	the	DET
ajst-18313	36	6	new	new	ADJ
ajst-18313	36	7	antibacterial	antibacterial	ADJ
ajst-18313	36	8	material	material	NOUN
ajst-18313	36	9	represented	represent	VERB
ajst-18313	36	10	by	by	ADP
ajst-18313	36	11	nba3	nba3	NOUN
ajst-18313	36	12	can	can	AUX
ajst-18313	36	13	reach	reach	VERB
ajst-18313	36	14	85	85	NUM
ajst-18313	36	15	℃	℃	PROPN
ajst-18313	36	16	,	,	PUNCT
ajst-18313	36	17	which	which	PRON
ajst-18313	36	18	is	be	AUX
ajst-18313	36	19	the	the	DET
ajst-18313	36	20	highest	high	ADJ
ajst-18313	36	21	temperature	temperature	NOUN
ajst-18313	36	22	found	find	VERB
ajst-18313	36	23	at	at	ADP
ajst-18313	36	24	present	present	NOUN
ajst-18313	36	25	[	[	X
ajst-18313	36	26	5	5	NUM
ajst-18313	36	27	]	]	PUNCT
ajst-18313	36	28	.	.	PUNCT
ajst-18313	37	1	due	due	ADP
ajst-18313	37	2	to	to	ADP
ajst-18313	37	3	its	its	PRON
ajst-18313	37	4	good	good	ADJ
ajst-18313	37	5	folding	folding	NOUN
ajst-18313	37	6	ability	ability	NOUN
ajst-18313	37	7	,	,	PUNCT
ajst-18313	37	8	the	the	DET
ajst-18313	37	9	material	material	NOUN
ajst-18313	37	10	is	be	AUX
ajst-18313	37	11	expected	expect	VERB
ajst-18313	37	12	to	to	PART
ajst-18313	37	13	be	be	AUX
ajst-18313	37	14	used	use	VERB
ajst-18313	37	15	in	in	ADP
ajst-18313	37	16	high	high	ADJ
ajst-18313	37	17	temperature	temperature	NOUN
ajst-18313	37	18	environments	environment	NOUN
ajst-18313	37	19	(	(	PUNCT
ajst-18313	37	20	such	such	ADJ
ajst-18313	37	21	as	as	ADP
ajst-18313	37	22	50	50	NUM
ajst-18313	37	23	°	°	NOUN
ajst-18313	37	24	c	c	NOUN
ajst-18313	37	25	)	)	PUNCT
ajst-18313	37	26	for	for	ADP
ajst-18313	37	27	the	the	DET
ajst-18313	37	28	detection	detection	NOUN
ajst-18313	37	29	of	of	ADP
ajst-18313	37	30	as	as	ADP
ajst-18313	37	31	inflammatory	inflammatory	ADJ
ajst-18313	37	32	indicators	indicator	NOUN
ajst-18313	37	33	.	.	PUNCT
ajst-18313	38	1	the	the	DET
ajst-18313	38	2	tm	tm	PROPN
ajst-18313	38	3	measurements	measurement	NOUN
ajst-18313	38	4	of	of	ADP
ajst-18313	38	5	conventional	conventional	ADJ
ajst-18313	38	6	fab	fab	NOUN
ajst-18313	38	7	and	and	CCONJ
ajst-18313	38	8	scfv	scfv	NOUN
ajst-18313	38	9	are	be	AUX
ajst-18313	38	10	not	not	PART
ajst-18313	38	11	much	much	ADV
ajst-18313	38	12	different	different	ADJ
ajst-18313	38	13	from	from	ADP
ajst-18313	38	14	those	those	PRON
ajst-18313	38	15	of	of	ADP
ajst-18313	38	16	ordinary	ordinary	ADJ
ajst-18313	38	17	nanoantibodies	nanoantibodie	NOUN
ajst-18313	38	18	,	,	PUNCT
ajst-18313	38	19	indicating	indicate	VERB
ajst-18313	38	20	that	that	SCONJ
ajst-18313	38	21	there	there	PRON
ajst-18313	38	22	is	be	VERB
ajst-18313	38	23	a	a	DET
ajst-18313	38	24	certain	certain	ADJ
ajst-18313	38	25	thermal	thermal	ADJ
ajst-18313	38	26	equilibrium	equilibrium	NOUN
ajst-18313	38	27	between	between	ADP
ajst-18313	38	28	them	they	PRON
ajst-18313	38	29	,	,	PUNCT
ajst-18313	38	30	but	but	CCONJ
ajst-18313	38	31	their	their	PRON
ajst-18313	38	32	reversible	reversible	ADJ
ajst-18313	38	33	properties	property	NOUN
ajst-18313	38	34	at	at	ADP
ajst-18313	38	35	ultra	ultra	ADJ
ajst-18313	38	36	-	-	ADJ
ajst-18313	38	37	low	low	ADJ
ajst-18313	38	38	temperatures	temperature	NOUN
ajst-18313	38	39	are	be	AUX
ajst-18313	38	40	different	different	ADJ
ajst-18313	38	41	.	.	PUNCT
ajst-18313	39	1	after	after	ADP
ajst-18313	39	2	incubation	incubation	NOUN
ajst-18313	39	3	at	at	ADP
ajst-18313	39	4	a	a	DET
ajst-18313	39	5	certain	certain	ADJ
ajst-18313	39	6	temperature	temperature	NOUN
ajst-18313	39	7	,	,	PUNCT
ajst-18313	39	8	the	the	DET
ajst-18313	39	9	activity	activity	NOUN
ajst-18313	39	10	of	of	ADP
ajst-18313	39	11	the	the	DET
ajst-18313	39	12	nanoantibody	nanoantibody	NOUN
ajst-18313	39	13	was	be	AUX
ajst-18313	39	14	measured	measure	VERB
ajst-18313	39	15	,	,	PUNCT
ajst-18313	39	16	and	and	CCONJ
ajst-18313	39	17	the	the	DET
ajst-18313	39	18	reversibility	reversibility	NOUN
ajst-18313	39	19	of	of	ADP
ajst-18313	39	20	the	the	DET
ajst-18313	39	21	process	process	NOUN
ajst-18313	39	22	could	could	AUX
ajst-18313	39	23	be	be	AUX
ajst-18313	39	24	determined	determine	VERB
ajst-18313	39	25	[	[	PUNCT
ajst-18313	39	26	6	6	NUM
ajst-18313	39	27	]	]	PUNCT
ajst-18313	39	28	.	.	PUNCT
ajst-18313	40	1	by	by	ADP
ajst-18313	40	2	summarizing	summarize	VERB
ajst-18313	40	3	the	the	DET
ajst-18313	40	4	results	result	NOUN
ajst-18313	40	5	of	of	ADP
ajst-18313	40	6	the	the	DET
ajst-18313	40	7	existing	exist	VERB
ajst-18313	40	8	studies	study	NOUN
ajst-18313	40	9	,	,	PUNCT
ajst-18313	40	10	most	most	ADJ
ajst-18313	40	11	of	of	ADP
ajst-18313	40	12	the	the	DET
ajst-18313	40	13	nano	nano	NOUN
ajst-18313	40	14	-	-	PUNCT
ajst-18313	40	15	antibodies	antibody	NOUN
ajst-18313	40	16	still	still	ADV
ajst-18313	40	17	have	have	VERB
ajst-18313	40	18	a	a	DET
ajst-18313	40	19	certain	certain	ADJ
ajst-18313	40	20	adsorption	adsorption	NOUN
ajst-18313	40	21	capacity	capacity	NOUN
ajst-18313	40	22	after	after	ADP
ajst-18313	40	23	long	long	ADJ
ajst-18313	40	24	-	-	PUNCT
ajst-18313	40	25	term	term	NOUN
ajst-18313	40	26	action	action	NOUN
ajst-18313	40	27	at	at	ADP
ajst-18313	40	28	temperatures	temperature	NOUN
ajst-18313	40	29	above	above	ADP
ajst-18313	40	30	85	85	NUM
ajst-18313	40	31	degrees	degree	NOUN
ajst-18313	40	32	celsius	celsius	NOUN
ajst-18313	40	33	,	,	PUNCT
ajst-18313	40	34	while	while	SCONJ
ajst-18313	40	35	other	other	ADJ
ajst-18313	40	36	traditional	traditional	ADJ
ajst-18313	40	37	antibodies	antibody	NOUN
ajst-18313	40	38	show	show	VERB
ajst-18313	40	39	irreversible	irreversible	ADJ
ajst-18313	40	40	inactivation	inactivation	NOUN
ajst-18313	40	41	.	.	PUNCT
ajst-18313	41	1	anticaffeine	anticaffeine	PROPN
ajst-18313	41	2	nb	nb	PROPN
ajst-18313	41	3	represented	represent	VERB
ajst-18313	41	4	by	by	ADP
ajst-18313	41	5	caffeine	caffeine	NOUN
ajst-18313	41	6	resistant	resistant	ADJ
ajst-18313	41	7	nb	nb	INTJ
ajst-18313	41	8	was	be	AUX
ajst-18313	41	9	incubated	incubate	VERB
ajst-18313	41	10	at	at	ADP
ajst-18313	41	11	90	90	NUM
ajst-18313	41	12	°	°	NOUN
ajst-18313	41	13	c	c	NOUN
ajst-18313	41	14	,	,	PUNCT
ajst-18313	41	15	and	and	CCONJ
ajst-18313	41	16	its	its	PRON
ajst-18313	41	17	mab	mab	NOUN
ajst-18313	41	18	was	be	AUX
ajst-18313	41	19	easily	easily	ADV
ajst-18313	41	20	inactivated	inactivate	VERB
ajst-18313	41	21	at	at	ADP
ajst-18313	41	22	70	70	NUM
ajst-18313	41	23	°	°	PROPN
ajst-18313	41	24	c.	c.	PROPN
ajst-18313	41	25	nb	nb	PROPN
ajst-18313	41	26	,	,	PUNCT
ajst-18313	41	27	which	which	PRON
ajst-18313	41	28	is	be	AUX
ajst-18313	41	29	resistant	resistant	ADJ
ajst-18313	41	30	to	to	ADP
ajst-18313	41	31	high	high	ADJ
ajst-18313	41	32	temperatures	temperature	NOUN
ajst-18313	41	33	,	,	PUNCT
ajst-18313	41	34	has	have	AUX
ajst-18313	41	35	filed	file	VERB
ajst-18313	41	36	a	a	DET
ajst-18313	41	37	patent	patent	NOUN
ajst-18313	41	38	for	for	ADP
ajst-18313	41	39	a	a	DET
ajst-18313	41	40	device	device	NOUN
ajst-18313	41	41	that	that	PRON
ajst-18313	41	42	could	could	AUX
ajst-18313	41	43	be	be	AUX
ajst-18313	41	44	used	use	VERB
ajst-18313	41	45	to	to	PART
ajst-18313	41	46	monitor	monitor	VERB
ajst-18313	41	47	caffeine	caffeine	NOUN
ajst-18313	41	48	in	in	ADP
ajst-18313	41	49	hot	hot	ADJ
ajst-18313	41	50	drinks	drink	NOUN
ajst-18313	41	51	.	.	PUNCT
ajst-18313	42	1	previous	previous	ADJ
ajst-18313	42	2	studies	study	NOUN
ajst-18313	42	3	of	of	ADP
ajst-18313	42	4	our	our	PRON
ajst-18313	42	5	research	research	NOUN
ajst-18313	42	6	group	group	NOUN
ajst-18313	42	7	found	find	VERB
ajst-18313	42	8	that	that	SCONJ
ajst-18313	42	9	in	in	ADP
ajst-18313	42	10	pasteurization	pasteurization	NOUN
ajst-18313	42	11	and	and	CCONJ
ajst-18313	42	12	other	other	ADJ
ajst-18313	42	13	environments	environment	NOUN
ajst-18313	42	14	,	,	PUNCT
ajst-18313	42	15	the	the	DET
ajst-18313	42	16	heat	heat	NOUN
ajst-18313	42	17	resistance	resistance	NOUN
ajst-18313	42	18	of	of	ADP
ajst-18313	42	19	its	its	PRON
ajst-18313	42	20	anti	anti	NOUN
ajst-18313	42	21	-	-	NOUN
ajst-18313	42	22	aflatoxins	aflatoxin	NOUN
ajst-18313	42	23	(	(	PUNCT
ajst-18313	42	24	nb	nb	NOUN
ajst-18313	42	25	-	-	PUNCT
ajst-18313	42	26	nb	nb	NOUN
ajst-18313	42	27	)	)	PUNCT
ajst-18313	42	28	and	and	CCONJ
ajst-18313	42	29	anti	anti	ADJ
ajst-18313	42	30	-	-	ADJ
ajst-18313	42	31	unique	unique	ADJ
ajst-18313	42	32	type	type	NOUN
ajst-18313	42	33	antibodies	antibody	NOUN
ajst-18313	42	34	(	(	PUNCT
ajst-18313	42	35	aid	aid	NOUN
ajst-18313	42	36	)	)	PUNCT
ajst-18313	42	37	was	be	AUX
ajst-18313	42	38	significantly	significantly	ADV
ajst-18313	42	39	stronger	strong	ADJ
ajst-18313	42	40	than	than	ADP
ajst-18313	42	41	that	that	PRON
ajst-18313	42	42	of	of	ADP
ajst-18313	42	43	traditional	traditional	ADJ
ajst-18313	42	44	antibodies	antibody	NOUN
ajst-18313	42	45	.	.	PUNCT
ajst-18313	43	1	after	after	ADP
ajst-18313	43	2	short	short	ADJ
ajst-18313	43	3	-	-	PUNCT
ajst-18313	43	4	term	term	NOUN
ajst-18313	43	5	incubation	incubation	NOUN
ajst-18313	43	6	,	,	PUNCT
ajst-18313	43	7	the	the	DET
ajst-18313	43	8	binding	bind	VERB
ajst-18313	43	9	ability	ability	NOUN
ajst-18313	43	10	of	of	ADP
ajst-18313	43	11	its	its	PRON
ajst-18313	43	12	polyclonal	polyclonal	ADJ
ajst-18313	43	13	antibodies	antibody	NOUN
ajst-18313	43	14	(	(	PUNCT
ajst-18313	43	15	pab	pab	NOUN
ajst-18313	43	16	)	)	PUNCT
ajst-18313	43	17	and	and	CCONJ
ajst-18313	43	18	monoclonal	monoclonal	NOUN
ajst-18313	43	19	antibodies	antibody	NOUN
ajst-18313	43	20	only	only	ADV
ajst-18313	43	21	maintained	maintain	VERB
ajst-18313	43	22	20	20	NUM
ajst-18313	43	23	%	%	NOUN
ajst-18313	43	24	or	or	CCONJ
ajst-18313	43	25	disappeared	disappear	VERB
ajst-18313	43	26	completely	completely	ADV
ajst-18313	43	27	,	,	PUNCT
ajst-18313	43	28	and	and	CCONJ
ajst-18313	43	29	after	after	ADP
ajst-18313	43	30	incubating	incubate	VERB
ajst-18313	43	31	at	at	ADP
ajst-18313	43	32	the	the	DET
ajst-18313	43	33	same	same	ADJ
ajst-18313	43	34	constant	constant	ADJ
ajst-18313	43	35	temperature	temperature	NOUN
ajst-18313	43	36	for	for	ADP
ajst-18313	43	37	20	20	NUM
ajst-18313	43	38	minutes	minute	NOUN
ajst-18313	43	39	or	or	CCONJ
ajst-18313	43	40	even	even	ADV
ajst-18313	43	41	1	1	NUM
ajst-18313	43	42	hour	hour	NOUN
ajst-18313	43	43	,	,	PUNCT
ajst-18313	43	44	its	its	PRON
ajst-18313	43	45	specific	specific	ADJ
ajst-18313	43	46	recognition	recognition	NOUN
ajst-18313	43	47	ability	ability	NOUN
ajst-18313	43	48	is	be	AUX
ajst-18313	43	49	still	still	ADV
ajst-18313	43	50	40%-80	40%-80	NUM
ajst-18313	43	51	%	%	NOUN
ajst-18313	43	52	,	,	PUNCT
ajst-18313	43	53	and	and	CCONJ
ajst-18313	43	54	it	it	PRON
ajst-18313	43	55	is	be	AUX
ajst-18313	43	56	expected	expect	VERB
ajst-18313	43	57	to	to	PART
ajst-18313	43	58	be	be	AUX
ajst-18313	43	59	applied	apply	VERB
ajst-18313	43	60	to	to	ADP
ajst-18313	43	61	aflatoxin	aflatoxin	NOUN
ajst-18313	43	62	analysis	analysis	NOUN
ajst-18313	43	63	in	in	ADP
ajst-18313	43	64	complex	complex	ADJ
ajst-18313	43	65	environments	environment	NOUN
ajst-18313	43	66	such	such	ADJ
ajst-18313	43	67	as	as	ADP
ajst-18313	43	68	pasteurization	pasteurization	NOUN
ajst-18313	43	69	[	[	X
ajst-18313	43	70	7	7	NUM
ajst-18313	43	71	]	]	PUNCT
ajst-18313	43	72	.	.	PUNCT
ajst-18313	44	1	therefore	therefore	ADV
ajst-18313	44	2	,	,	PUNCT
ajst-18313	44	3	compared	compare	VERB
ajst-18313	44	4	with	with	ADP
ajst-18313	44	5	conventional	conventional	ADJ
ajst-18313	44	6	antibodies	antibody	NOUN
ajst-18313	44	7	,	,	PUNCT
ajst-18313	44	8	nano	nano	NOUN
ajst-18313	44	9	-	-	PUNCT
ajst-18313	44	10	antibodies	antibody	NOUN
ajst-18313	44	11	show	show	VERB
ajst-18313	44	12	greater	great	ADJ
ajst-18313	44	13	advantages	advantage	NOUN
ajst-18313	44	14	in	in	ADP
ajst-18313	44	15	complex	complex	ADJ
ajst-18313	44	16	temperature	temperature	NOUN
ajst-18313	44	17	changing	change	VERB
ajst-18313	44	18	environments	environment	NOUN
ajst-18313	44	19	.	.	PUNCT
ajst-18313	45	1	figure	figure	NOUN
ajst-18313	45	2	2	2	NUM
ajst-18313	45	3	shows	show	VERB
ajst-18313	45	4	the	the	DET
ajst-18313	45	5	heat	heat	NOUN
ajst-18313	45	6	resistance	resistance	NOUN
ajst-18313	45	7	experimental	experimental	ADJ
ajst-18313	45	8	process	process	NOUN
ajst-18313	45	9	of	of	ADP
ajst-18313	45	10	the	the	DET
ajst-18313	45	11	nanoantibody	nanoantibody	NOUN
ajst-18313	45	12	(	(	PUNCT
ajst-18313	45	13	the	the	DET
ajst-18313	45	14	picture	picture	NOUN
ajst-18313	45	15	is	be	AUX
ajst-18313	45	16	quoted	quote	VERB
ajst-18313	45	17	in	in	ADP
ajst-18313	45	18	applications	application	NOUN
ajst-18313	45	19	of	of	ADP
ajst-18313	45	20	nanobodies	nanobodie	NOUN
ajst-18313	45	21	in	in	ADP
ajst-18313	45	22	brain	brain	NOUN
ajst-18313	45	23	diseases	disease	NOUN
ajst-18313	45	24	)	)	PUNCT
ajst-18313	45	25	.	.	PUNCT
ajst-18313	46	1	figure	figure	NOUN
ajst-18313	46	2	2	2	NUM
ajst-18313	46	3	.	.	PUNCT
ajst-18313	46	4	heat	heat	NOUN
ajst-18313	46	5	resistance	resistance	NOUN
ajst-18313	46	6	test	test	NOUN
ajst-18313	46	7	process	process	NOUN
ajst-18313	46	8	of	of	ADP
ajst-18313	46	9	nano	nano	NOUN
ajst-18313	46	10	antibody	antibody	NOUN
ajst-18313	46	11	11	11	NUM
ajst-18313	46	12	3.2	3.2	NUM
ajst-18313	46	13	.	.	PUNCT
ajst-18313	47	1	organic	organic	ADJ
ajst-18313	47	2	solvent	solvent	NOUN
ajst-18313	47	3	tolerance	tolerance	NOUN
ajst-18313	47	4	at	at	ADP
ajst-18313	47	5	present	present	ADJ
ajst-18313	47	6	,	,	PUNCT
ajst-18313	47	7	the	the	DET
ajst-18313	47	8	immunoassay	immunoassay	PROPN
ajst-18313	47	9	technology	technology	NOUN
ajst-18313	47	10	used	use	VERB
ajst-18313	47	11	for	for	ADP
ajst-18313	47	12	the	the	DET
ajst-18313	47	13	detection	detection	NOUN
ajst-18313	47	14	of	of	ADP
ajst-18313	47	15	lipophilic	lipophilic	ADJ
ajst-18313	47	16	substances	substance	NOUN
ajst-18313	47	17	mostly	mostly	ADV
ajst-18313	47	18	uses	use	VERB
ajst-18313	47	19	organic	organic	ADJ
ajst-18313	47	20	solvents	solvent	NOUN
ajst-18313	47	21	.	.	PUNCT
ajst-18313	48	1	however	however	ADV
ajst-18313	48	2	,	,	PUNCT
ajst-18313	48	3	the	the	DET
ajst-18313	48	4	existence	existence	NOUN
ajst-18313	48	5	of	of	ADP
ajst-18313	48	6	organic	organic	ADJ
ajst-18313	48	7	solvents	solvent	NOUN
ajst-18313	48	8	interferes	interfere	VERB
ajst-18313	48	9	with	with	ADP
ajst-18313	48	10	the	the	DET
ajst-18313	48	11	activity	activity	NOUN
ajst-18313	48	12	of	of	ADP
ajst-18313	48	13	antibodies	antibody	NOUN
ajst-18313	48	14	to	to	ADP
ajst-18313	48	15	a	a	DET
ajst-18313	48	16	certain	certain	ADJ
ajst-18313	48	17	extent	extent	NOUN
ajst-18313	48	18	.	.	PUNCT
ajst-18313	49	1	therefore	therefore	ADV
ajst-18313	49	2	,	,	PUNCT
ajst-18313	49	3	the	the	DET
ajst-18313	49	4	interference	interference	NOUN
ajst-18313	49	5	of	of	ADP
ajst-18313	49	6	these	these	DET
ajst-18313	49	7	factors	factor	NOUN
ajst-18313	49	8	must	must	AUX
ajst-18313	49	9	be	be	AUX
ajst-18313	49	10	eliminated	eliminate	VERB
ajst-18313	49	11	by	by	ADP
ajst-18313	49	12	means	mean	NOUN
ajst-18313	49	13	of	of	ADP
ajst-18313	49	14	volatilization	volatilization	NOUN
ajst-18313	49	15	and	and	CCONJ
ajst-18313	49	16	high	high	ADJ
ajst-18313	49	17	proportion	proportion	NOUN
ajst-18313	49	18	dilution	dilution	NOUN
ajst-18313	49	19	[	[	X
ajst-18313	49	20	8	8	NUM
ajst-18313	49	21	]	]	PUNCT
ajst-18313	49	22	.	.	PUNCT
ajst-18313	50	1	the	the	DET
ajst-18313	50	2	selection	selection	NOUN
ajst-18313	50	3	of	of	ADP
ajst-18313	50	4	antibodies	antibody	NOUN
ajst-18313	50	5	with	with	ADP
ajst-18313	50	6	good	good	ADJ
ajst-18313	50	7	tolerance	tolerance	NOUN
ajst-18313	50	8	to	to	ADP
ajst-18313	50	9	organic	organic	ADJ
ajst-18313	50	10	solutions	solution	NOUN
ajst-18313	50	11	can	can	AUX
ajst-18313	50	12	eliminate	eliminate	VERB
ajst-18313	50	13	the	the	DET
ajst-18313	50	14	volatile	volatile	ADJ
ajst-18313	50	15	resolution	resolution	NOUN
ajst-18313	50	16	process	process	NOUN
ajst-18313	50	17	,	,	PUNCT
ajst-18313	50	18	and	and	CCONJ
ajst-18313	50	19	can	can	AUX
ajst-18313	50	20	effectively	effectively	ADV
ajst-18313	50	21	prevent	prevent	VERB
ajst-18313	50	22	the	the	DET
ajst-18313	50	23	reduction	reduction	NOUN
ajst-18313	50	24	of	of	ADP
ajst-18313	50	25	detection	detection	NOUN
ajst-18313	50	26	sensitivity	sensitivity	NOUN
ajst-18313	50	27	due	due	ADP
ajst-18313	50	28	to	to	ADP
ajst-18313	50	29	high	high	ADJ
ajst-18313	50	30	concentration	concentration	NOUN
ajst-18313	50	31	dilution	dilution	NOUN
ajst-18313	50	32	.	.	PUNCT
ajst-18313	51	1	studies	study	NOUN
ajst-18313	51	2	have	have	AUX
ajst-18313	51	3	shown	show	VERB
ajst-18313	51	4	that	that	SCONJ
ajst-18313	51	5	most	most	ADJ
ajst-18313	51	6	of	of	ADP
ajst-18313	51	7	the	the	DET
ajst-18313	51	8	nano	nano	NOUN
ajst-18313	51	9	-	-	PUNCT
ajst-18313	51	10	antibodies	antibody	NOUN
ajst-18313	51	11	can	can	AUX
ajst-18313	51	12	resist	resist	VERB
ajst-18313	51	13	the	the	DET
ajst-18313	51	14	extraction	extraction	NOUN
ajst-18313	51	15	of	of	ADP
ajst-18313	51	16	high	high	ADJ
ajst-18313	51	17	concentrations	concentration	NOUN
ajst-18313	51	18	of	of	ADP
ajst-18313	51	19	methanol	methanol	NOUN
ajst-18313	51	20	,	,	PUNCT
ajst-18313	51	21	ethanol	ethanol	NOUN
ajst-18313	51	22	,	,	PUNCT
ajst-18313	51	23	acetonitrile	acetonitrile	NOUN
ajst-18313	51	24	,	,	PUNCT
ajst-18313	51	25	acetone	acetone	NOUN
ajst-18313	51	26	and	and	CCONJ
ajst-18313	51	27	dimethyl	dimethyl	NOUN
ajst-18313	51	28	sulfoxide	sulfoxide	NOUN
ajst-18313	51	29	.	.	PUNCT
ajst-18313	52	1	for	for	ADP
ajst-18313	52	2	example	example	NOUN
ajst-18313	52	3	,	,	PUNCT
ajst-18313	52	4	to	to	PART
ajst-18313	52	5	separate	separate	VERB
ajst-18313	52	6	otas	ota	NOUN
ajst-18313	52	7	from	from	ADP
ajst-18313	52	8	food	food	NOUN
ajst-18313	52	9	,	,	PUNCT
ajst-18313	52	10	methanol	methanol	NOUN
ajst-18313	52	11	must	must	AUX
ajst-18313	52	12	be	be	AUX
ajst-18313	52	13	used	use	VERB
ajst-18313	52	14	,	,	PUNCT
ajst-18313	52	15	and	and	CCONJ
ajst-18313	52	16	in	in	ADP
ajst-18313	52	17	this	this	DET
ajst-18313	52	18	process	process	NOUN
ajst-18313	52	19	,	,	PUNCT
ajst-18313	52	20	methanol	methanol	NOUN
ajst-18313	52	21	not	not	PART
ajst-18313	52	22	only	only	ADV
ajst-18313	52	23	interferes	interfere	VERB
ajst-18313	52	24	with	with	ADP
ajst-18313	52	25	the	the	DET
ajst-18313	52	26	binding	binding	NOUN
ajst-18313	52	27	of	of	ADP
ajst-18313	52	28	otas	otas	PROPN
ajst-18313	52	29	to	to	PART
ajst-18313	52	30	antibodies	antibodie	VERB
ajst-18313	52	31	,	,	PUNCT
ajst-18313	52	32	but	but	CCONJ
ajst-18313	52	33	also	also	ADV
ajst-18313	52	34	reduces	reduce	VERB
ajst-18313	52	35	the	the	DET
ajst-18313	52	36	ability	ability	NOUN
ajst-18313	52	37	of	of	ADP
ajst-18313	52	38	secondary	secondary	ADJ
ajst-18313	52	39	antibodies	antibody	NOUN
ajst-18313	52	40	.	.	PUNCT
ajst-18313	53	1	when	when	SCONJ
ajst-18313	53	2	tested	test	VERB
ajst-18313	53	3	,	,	PUNCT
ajst-18313	53	4	there	there	PRON
ajst-18313	53	5	was	be	VERB
ajst-18313	53	6	only	only	ADV
ajst-18313	53	7	a	a	DET
ajst-18313	53	8	small	small	ADJ
ajst-18313	53	9	amount	amount	NOUN
ajst-18313	53	10	of	of	ADP
ajst-18313	53	11	nb	nb	NOUN
ajst-18313	53	12	against	against	ADP
ajst-18313	53	13	ota	ota	PROPN
ajst-18313	53	14	in	in	ADP
ajst-18313	53	15	the	the	DET
ajst-18313	53	16	20	20	NUM
ajst-18313	53	17	%	%	NOUN
ajst-18313	53	18	methanol	methanol	NOUN
ajst-18313	53	19	.	.	PUNCT
ajst-18313	54	1	this	this	DET
ajst-18313	54	2	project	project	NOUN
ajst-18313	54	3	intends	intend	VERB
ajst-18313	54	4	to	to	PART
ajst-18313	54	5	use	use	VERB
ajst-18313	54	6	the	the	DET
ajst-18313	54	7	2.5	2.5	NUM
ajst-18313	54	8	-	-	PUNCT
ajst-18313	54	9	fold	fold	ADJ
ajst-18313	54	10	release	release	NOUN
ajst-18313	54	11	method	method	NOUN
ajst-18313	54	12	to	to	PART
ajst-18313	54	13	remove	remove	VERB
ajst-18313	54	14	matrix	matrix	NOUN
ajst-18313	54	15	interference	interference	NOUN
ajst-18313	54	16	,	,	PUNCT
ajst-18313	54	17	but	but	CCONJ
ajst-18313	54	18	the	the	DET
ajst-18313	54	19	detection	detection	NOUN
ajst-18313	54	20	of	of	ADP
ajst-18313	54	21	monoclonal	monoclonal	NOUN
ajst-18313	54	22	antibody	antibody	NOUN
ajst-18313	54	23	needs	need	VERB
ajst-18313	54	24	to	to	PART
ajst-18313	54	25	dilute	dilute	VERB
ajst-18313	54	26	the	the	DET
ajst-18313	54	27	concentration	concentration	NOUN
ajst-18313	54	28	of	of	ADP
ajst-18313	54	29	monoclonal	monoclonal	NOUN
ajst-18313	54	30	antibody	antibody	NOUN
ajst-18313	54	31	more	more	ADJ
ajst-18313	54	32	than	than	ADP
ajst-18313	54	33	30	30	NUM
ajst-18313	54	34	times	time	NOUN
ajst-18313	54	35	,	,	PUNCT
ajst-18313	54	36	showing	show	VERB
ajst-18313	54	37	a	a	DET
ajst-18313	54	38	strong	strong	ADJ
ajst-18313	54	39	ability	ability	NOUN
ajst-18313	54	40	to	to	PART
ajst-18313	54	41	resist	resist	VERB
ajst-18313	54	42	matrix	matrix	NOUN
ajst-18313	54	43	interference	interference	NOUN
ajst-18313	55	1	[	[	X
ajst-18313	55	2	9	9	NUM
ajst-18313	55	3	]	]	PUNCT
ajst-18313	55	4	.	.	PUNCT
ajst-18313	56	1	taking	take	VERB
ajst-18313	56	2	aflatoxin	aflatoxin	NOUN
ajst-18313	56	3	with	with	ADP
ajst-18313	56	4	strong	strong	ADJ
ajst-18313	56	5	fat	fat	ADJ
ajst-18313	56	6	solubility	solubility	NOUN
ajst-18313	56	7	as	as	ADP
ajst-18313	56	8	the	the	DET
ajst-18313	56	9	research	research	NOUN
ajst-18313	56	10	object	object	NOUN
ajst-18313	56	11	,	,	PUNCT
ajst-18313	56	12	niobium	niobium	NOUN
ajst-18313	56	13	has	have	VERB
ajst-18313	56	14	100	100	NUM
ajst-18313	56	15	%	%	NOUN
ajst-18313	56	16	affinity	affinity	NOUN
ajst-18313	56	17	for	for	ADP
ajst-18313	56	18	it	it	PRON
ajst-18313	56	19	at	at	ADP
ajst-18313	56	20	80	80	NUM
ajst-18313	56	21	%	%	NOUN
ajst-18313	56	22	ethanol	ethanol	NOUN
ajst-18313	56	23	concentration	concentration	NOUN
ajst-18313	56	24	,	,	PUNCT
ajst-18313	56	25	but	but	CCONJ
ajst-18313	56	26	it	it	PRON
ajst-18313	56	27	loses	lose	VERB
ajst-18313	56	28	more	more	ADJ
ajst-18313	56	29	than	than	ADP
ajst-18313	56	30	50	50	NUM
ajst-18313	56	31	%	%	NOUN
ajst-18313	56	32	of	of	ADP
ajst-18313	56	33	its	its	PRON
ajst-18313	56	34	monoantibody	monoantibody	NOUN
ajst-18313	57	1	[	[	X
ajst-18313	57	2	10	10	NUM
ajst-18313	57	3	]	]	PUNCT
ajst-18313	57	4	.	.	PUNCT
ajst-18313	58	1	its	its	PRON
ajst-18313	58	2	anti	anti	ADJ
ajst-18313	58	3	-	-	ADJ
ajst-18313	58	4	organic	organic	ADJ
ajst-18313	58	5	solvent	solvent	NOUN
ajst-18313	58	6	property	property	NOUN
ajst-18313	58	7	not	not	PART
ajst-18313	58	8	only	only	ADV
ajst-18313	58	9	can	can	AUX
ajst-18313	58	10	easily	easily	ADV
ajst-18313	58	11	determine	determine	VERB
ajst-18313	58	12	the	the	DET
ajst-18313	58	13	lipophilic	lipophilic	ADJ
ajst-18313	58	14	components	component	NOUN
ajst-18313	58	15	in	in	ADP
ajst-18313	58	16	the	the	DET
ajst-18313	58	17	samples	sample	NOUN
ajst-18313	58	18	to	to	PART
ajst-18313	58	19	be	be	AUX
ajst-18313	58	20	tested	test	VERB
ajst-18313	58	21	,	,	PUNCT
ajst-18313	58	22	but	but	CCONJ
ajst-18313	58	23	also	also	ADV
ajst-18313	58	24	can	can	AUX
ajst-18313	58	25	be	be	AUX
ajst-18313	58	26	used	use	VERB
ajst-18313	58	27	in	in	ADP
ajst-18313	58	28	the	the	DET
ajst-18313	58	29	development	development	NOUN
ajst-18313	58	30	of	of	ADP
ajst-18313	58	31	low	low	ADJ
ajst-18313	58	32	concentration	concentration	NOUN
ajst-18313	58	33	affinity	affinity	NOUN
ajst-18313	58	34	chromatography	chromatography	NOUN
ajst-18313	58	35	.	.	PUNCT
ajst-18313	59	1	3.3	3.3	NUM
ajst-18313	59	2	.	.	PUNCT
ajst-18313	60	1	stress	stress	NOUN
ajst-18313	60	2	tolerance	tolerance	NOUN
ajst-18313	60	3	it	it	PRON
ajst-18313	60	4	has	have	AUX
ajst-18313	60	5	been	be	AUX
ajst-18313	60	6	reported	report	VERB
ajst-18313	60	7	that	that	SCONJ
ajst-18313	60	8	human	human	ADJ
ajst-18313	60	9	lysozyme	lysozyme	NOUN
ajst-18313	60	10	/	/	SYM
ajst-18313	60	11	azo	azo	NOUN
ajst-18313	60	12	stained	stain	VERB
ajst-18313	60	13	rr6	rr6	VERB
ajst-18313	60	14	nanoantibodies	nanoantibodie	NOUN
ajst-18313	60	15	can	can	AUX
ajst-18313	60	16	denaturate	denaturate	VERB
ajst-18313	60	17	and	and	CCONJ
ajst-18313	60	18	fold	fold	VERB
ajst-18313	60	19	under	under	ADV
ajst-18313	60	20	high	high	ADJ
ajst-18313	60	21	pressure	pressure	NOUN
ajst-18313	60	22	above	above	ADP
ajst-18313	60	23	400	400	NUM
ajst-18313	60	24	mpa	mpa	NOUN
ajst-18313	60	25	,	,	PUNCT
ajst-18313	60	26	revealing	reveal	VERB
ajst-18313	60	27	the	the	DET
ajst-18313	60	28	stability	stability	NOUN
ajst-18313	60	29	mechanism	mechanism	NOUN
ajst-18313	60	30	of	of	ADP
ajst-18313	60	31	nb	nb	INTJ
ajst-18313	60	32	under	under	ADP
ajst-18313	60	33	high	high	ADJ
ajst-18313	60	34	pressure	pressure	NOUN
ajst-18313	60	35	.	.	PUNCT
ajst-18313	61	1	in	in	ADP
ajst-18313	61	2	addition	addition	NOUN
ajst-18313	61	3	,	,	PUNCT
ajst-18313	61	4	the	the	DET
ajst-18313	61	5	non	non	ADJ
ajst-18313	61	6	-	-	ADJ
ajst-18313	61	7	covalent	covalent	ADJ
ajst-18313	61	8	protein	protein	NOUN
ajst-18313	61	9	complex	complex	NOUN
ajst-18313	61	10	can	can	AUX
ajst-18313	61	11	also	also	ADV
ajst-18313	61	12	be	be	AUX
ajst-18313	61	13	rapidly	rapidly	ADV
ajst-18313	61	14	dissociated	dissociate	VERB
ajst-18313	61	15	under	under	ADP
ajst-18313	61	16	low	low	ADJ
ajst-18313	61	17	pressure	pressure	NOUN
ajst-18313	61	18	,	,	PUNCT
ajst-18313	61	19	so	so	SCONJ
ajst-18313	61	20	that	that	SCONJ
ajst-18313	61	21	it	it	PRON
ajst-18313	61	22	can	can	AUX
ajst-18313	61	23	be	be	AUX
ajst-18313	61	24	effectively	effectively	ADV
ajst-18313	61	25	separated	separate	VERB
ajst-18313	61	26	under	under	ADP
ajst-18313	61	27	this	this	DET
ajst-18313	61	28	high	high	ADJ
ajst-18313	61	29	pressure	pressure	NOUN
ajst-18313	61	30	.	.	PUNCT
ajst-18313	62	1	this	this	DET
ajst-18313	62	2	method	method	NOUN
ajst-18313	62	3	can	can	AUX
ajst-18313	62	4	be	be	AUX
ajst-18313	62	5	used	use	VERB
ajst-18313	62	6	to	to	PART
ajst-18313	62	7	achieve	achieve	VERB
ajst-18313	62	8	high	high	ADJ
ajst-18313	62	9	selectivity	selectivity	NOUN
ajst-18313	62	10	,	,	PUNCT
ajst-18313	62	11	high	high	ADJ
ajst-18313	62	12	selectivity	selectivity	NOUN
ajst-18313	62	13	,	,	PUNCT
ajst-18313	62	14	high	high	ADJ
ajst-18313	62	15	selectivity	selectivity	NOUN
ajst-18313	62	16	of	of	ADP
ajst-18313	62	17	specific	specific	ADJ
ajst-18313	62	18	antigens	antigen	NOUN
ajst-18313	62	19	and	and	CCONJ
ajst-18313	62	20	antigen	antigen	ADJ
ajst-18313	62	21	molecules	molecule	NOUN
ajst-18313	62	22	.	.	PUNCT
ajst-18313	63	1	at	at	ADP
ajst-18313	63	2	the	the	DET
ajst-18313	63	3	same	same	ADJ
ajst-18313	63	4	time	time	NOUN
ajst-18313	63	5	,	,	PUNCT
ajst-18313	63	6	the	the	DET
ajst-18313	63	7	technology	technology	NOUN
ajst-18313	63	8	has	have	VERB
ajst-18313	63	9	the	the	DET
ajst-18313	63	10	characteristics	characteristic	NOUN
ajst-18313	63	11	of	of	ADP
ajst-18313	63	12	high	high	ADJ
ajst-18313	63	13	pressure	pressure	NOUN
ajst-18313	63	14	resistance	resistance	NOUN
ajst-18313	63	15	,	,	PUNCT
ajst-18313	63	16	low	low	ADJ
ajst-18313	63	17	dosage	dosage	NOUN
ajst-18313	63	18	and	and	CCONJ
ajst-18313	63	19	high	high	ADJ
ajst-18313	63	20	solubility	solubility	NOUN
ajst-18313	63	21	,	,	PUNCT
ajst-18313	63	22	which	which	PRON
ajst-18313	63	23	will	will	AUX
ajst-18313	63	24	also	also	ADV
ajst-18313	63	25	lay	lay	VERB
ajst-18313	63	26	a	a	DET
ajst-18313	63	27	foundation	foundation	NOUN
ajst-18313	63	28	for	for	ADP
ajst-18313	63	29	the	the	DET
ajst-18313	63	30	research	research	NOUN
ajst-18313	63	31	and	and	CCONJ
ajst-18313	63	32	development	development	NOUN
ajst-18313	63	33	of	of	ADP
ajst-18313	63	34	a	a	DET
ajst-18313	63	35	new	new	ADJ
ajst-18313	63	36	type	type	NOUN
ajst-18313	63	37	of	of	ADP
ajst-18313	63	38	respiratory	respiratory	ADJ
ajst-18313	63	39	inhalation	inhalation	NOUN
ajst-18313	63	40	drug	drug	NOUN
ajst-18313	63	41	[	[	X
ajst-18313	63	42	11	11	NUM
ajst-18313	63	43	]	]	PUNCT
ajst-18313	63	44	.	.	PUNCT
ajst-18313	64	1	at	at	ADP
ajst-18313	64	2	present	present	ADJ
ajst-18313	64	3	,	,	PUNCT
ajst-18313	64	4	nnbalx-0171	nnbalx-0171	ADJ
ajst-18313	64	5	trimer	trimer	NOUN
ajst-18313	64	6	is	be	AUX
ajst-18313	64	7	in	in	ADP
ajst-18313	64	8	phase	phase	NOUN
ajst-18313	64	9	ii	ii	NOUN
ajst-18313	64	10	clinical	clinical	ADJ
ajst-18313	64	11	trials	trial	NOUN
ajst-18313	64	12	and	and	CCONJ
ajst-18313	64	13	can	can	AUX
ajst-18313	64	14	significantly	significantly	ADV
ajst-18313	64	15	reduce	reduce	VERB
ajst-18313	64	16	rsv	rsv	PROPN
ajst-18313	64	17	infection	infection	NOUN
ajst-18313	64	18	in	in	ADP
ajst-18313	64	19	children	child	NOUN
ajst-18313	64	20	through	through	ADP
ajst-18313	64	21	aerosol	aerosol	NOUN
ajst-18313	64	22	administration	administration	NOUN
ajst-18313	64	23	.	.	PUNCT
ajst-18313	65	1	pin-21	pin-21	NOUN
ajst-18313	65	2	,	,	PUNCT
ajst-18313	65	3	also	also	ADV
ajst-18313	65	4	trimeric	trimeric	PROPN
ajst-18313	65	5	nb	nb	PROPN
ajst-18313	65	6	,	,	PUNCT
ajst-18313	65	7	is	be	AUX
ajst-18313	65	8	also	also	ADV
ajst-18313	65	9	stable	stable	ADJ
ajst-18313	65	10	when	when	SCONJ
ajst-18313	65	11	sprayed	spray	VERB
ajst-18313	65	12	with	with	ADP
ajst-18313	65	13	urea	urea	NOUN
ajst-18313	65	14	and	and	CCONJ
ajst-18313	65	15	guanidine	guanidine	ADJ
ajst-18313	65	16	hydrochloride	hydrochloride	NOUN
ajst-18313	65	17	and	and	CCONJ
ajst-18313	65	18	can	can	AUX
ajst-18313	65	19	be	be	AUX
ajst-18313	65	20	used	use	VERB
ajst-18313	65	21	with	with	ADP
ajst-18313	65	22	shampoo	shampoo	NOUN
ajst-18313	65	23	to	to	PART
ajst-18313	65	24	prevent	prevent	VERB
ajst-18313	65	25	dandruff	dandruff	NOUN
ajst-18313	65	26	.	.	PUNCT
ajst-18313	66	1	however	however	ADV
ajst-18313	66	2	,	,	PUNCT
ajst-18313	66	3	it	it	PRON
ajst-18313	66	4	is	be	AUX
ajst-18313	66	5	not	not	PART
ajst-18313	66	6	all	all	PRON
ajst-18313	66	7	negative	negative	ADJ
ajst-18313	66	8	,	,	PUNCT
ajst-18313	66	9	for	for	ADP
ajst-18313	66	10	example	example	NOUN
ajst-18313	66	11	,	,	PUNCT
ajst-18313	66	12	listeria	listeria	PROPN
ajst-18313	66	13	nb	nb	NOUN
ajst-18313	66	14	enhances	enhance	VERB
ajst-18313	66	15	its	its	PRON
ajst-18313	66	16	ability	ability	NOUN
ajst-18313	66	17	to	to	PART
ajst-18313	66	18	bind	bind	VERB
ajst-18313	66	19	to	to	ADP
ajst-18313	66	20	antigens	antigen	NOUN
ajst-18313	66	21	at	at	ADP
ajst-18313	66	22	high	high	ADJ
ajst-18313	66	23	concentrations	concentration	NOUN
ajst-18313	66	24	,	,	PUNCT
ajst-18313	66	25	suggesting	suggest	VERB
ajst-18313	66	26	that	that	SCONJ
ajst-18313	66	27	it	it	PRON
ajst-18313	66	28	may	may	AUX
ajst-18313	66	29	be	be	AUX
ajst-18313	66	30	involved	involve	VERB
ajst-18313	66	31	in	in	ADP
ajst-18313	66	32	the	the	DET
ajst-18313	66	33	refolding	refolding	NOUN
ajst-18313	66	34	of	of	ADP
ajst-18313	66	35	some	some	DET
ajst-18313	66	36	nanoantibodies	nanoantibodie	NOUN
ajst-18313	66	37	.	.	PUNCT
ajst-18313	67	1	3.4	3.4	NUM
ajst-18313	67	2	.	.	PUNCT
ajst-18313	67	3	ph	ph	ADJ
ajst-18313	67	4	tolerance	tolerance	NOUN
ajst-18313	67	5	at	at	ADP
ajst-18313	67	6	various	various	ADJ
ajst-18313	67	7	ph	ph	NOUN
ajst-18313	67	8	,	,	PUNCT
ajst-18313	67	9	the	the	DET
ajst-18313	67	10	stability	stability	NOUN
ajst-18313	67	11	of	of	ADP
ajst-18313	67	12	the	the	DET
ajst-18313	67	13	nano	nano	NOUN
ajst-18313	67	14	-	-	PUNCT
ajst-18313	67	15	antibody	antibody	NOUN
ajst-18313	67	16	is	be	AUX
ajst-18313	67	17	basically	basically	ADV
ajst-18313	67	18	the	the	DET
ajst-18313	67	19	same	same	ADJ
ajst-18313	67	20	.	.	PUNCT
ajst-18313	68	1	for	for	ADP
ajst-18313	68	2	example	example	NOUN
ajst-18313	68	3	,	,	PUNCT
ajst-18313	68	4	some	some	DET
ajst-18313	68	5	scholars	scholar	NOUN
ajst-18313	68	6	have	have	AUX
ajst-18313	68	7	reported	report	VERB
ajst-18313	68	8	that	that	SCONJ
ajst-18313	68	9	an	an	DET
ajst-18313	68	10	nb	nb	NOUN
ajst-18313	68	11	antibody	antibody	NOUN
ajst-18313	68	12	against	against	ADP
ajst-18313	68	13	tetrabrombisphenol	tetrabrombisphenol	NOUN
ajst-18313	68	14	a	a	PRON
ajst-18313	68	15	has	have	VERB
ajst-18313	68	16	good	good	ADJ
ajst-18313	68	17	stability	stability	NOUN
ajst-18313	68	18	in	in	ADP
ajst-18313	68	19	the	the	DET
ajst-18313	68	20	ph	ph	ADJ
ajst-18313	68	21	range	range	NOUN
ajst-18313	68	22	of	of	ADP
ajst-18313	68	23	7.4	7.4	NUM
ajst-18313	68	24	-	-	SYM
ajst-18313	68	25	10	10	NUM
ajst-18313	68	26	.	.	PUNCT
ajst-18313	69	1	similarly	similarly	ADV
ajst-18313	69	2	,	,	PUNCT
ajst-18313	69	3	nb	nb	INTJ
ajst-18313	69	4	of	of	ADP
ajst-18313	69	5	listeria	listeria	NOUN
ajst-18313	69	6	is	be	AUX
ajst-18313	69	7	not	not	PART
ajst-18313	69	8	less	less	ADJ
ajst-18313	69	9	than	than	ADP
ajst-18313	69	10	30	30	NUM
ajst-18313	69	11	%	%	NOUN
ajst-18313	69	12	active	active	ADJ
ajst-18313	69	13	after	after	ADP
ajst-18313	69	14	being	be	AUX
ajst-18313	69	15	cultured	cultured	ADJ
ajst-18313	69	16	overnight	overnight	ADV
ajst-18313	69	17	in	in	ADP
ajst-18313	69	18	extremely	extremely	ADV
ajst-18313	69	19	acidic	acidic	ADJ
ajst-18313	69	20	and	and	CCONJ
ajst-18313	69	21	alkaline	alkaline	NOUN
ajst-18313	69	22	environments	environment	NOUN
ajst-18313	69	23	with	with	ADP
ajst-18313	69	24	ph	ph	ADJ
ajst-18313	69	25	values	value	NOUN
ajst-18313	69	26	of	of	ADP
ajst-18313	69	27	2	2	NUM
ajst-18313	69	28	and	and	CCONJ
ajst-18313	69	29	12	12	NUM
ajst-18313	69	30	.	.	PUNCT
ajst-18313	70	1	the	the	DET
ajst-18313	70	2	new	new	ADJ
ajst-18313	70	3	nanomaterials	nanomaterial	NOUN
ajst-18313	70	4	designed	design	VERB
ajst-18313	70	5	in	in	ADP
ajst-18313	70	6	this	this	DET
ajst-18313	70	7	project	project	NOUN
ajst-18313	70	8	will	will	AUX
ajst-18313	70	9	be	be	AUX
ajst-18313	70	10	affected	affect	VERB
ajst-18313	70	11	by	by	ADP
ajst-18313	70	12	the	the	DET
ajst-18313	70	13	degree	degree	NOUN
ajst-18313	70	14	of	of	ADP
ajst-18313	70	15	environmental	environmental	ADJ
ajst-18313	70	16	variation	variation	NOUN
ajst-18313	70	17	detected	detect	VERB
ajst-18313	70	18	when	when	SCONJ
ajst-18313	70	19	used	use	VERB
ajst-18313	70	20	in	in	ADP
ajst-18313	70	21	microfluidic	microfluidic	ADJ
ajst-18313	70	22	studies	study	NOUN
ajst-18313	70	23	.	.	PUNCT
ajst-18313	71	1	4	4	X
ajst-18313	71	2	.	.	X
ajst-18313	71	3	structural	structural	ADJ
ajst-18313	71	4	basis	basis	NOUN
ajst-18313	71	5	for	for	ADP
ajst-18313	71	6	stability	stability	NOUN
ajst-18313	71	7	because	because	SCONJ
ajst-18313	71	8	of	of	ADP
ajst-18313	71	9	its	its	PRON
ajst-18313	71	10	small	small	ADJ
ajst-18313	71	11	molecule	molecule	NOUN
ajst-18313	71	12	and	and	CCONJ
ajst-18313	71	13	single	single	ADJ
ajst-18313	71	14	structure	structure	NOUN
ajst-18313	71	15	,	,	PUNCT
ajst-18313	71	16	it	it	PRON
ajst-18313	71	17	is	be	AUX
ajst-18313	71	18	more	more	ADV
ajst-18313	71	19	stable	stable	ADJ
ajst-18313	71	20	than	than	ADP
ajst-18313	71	21	traditional	traditional	ADJ
ajst-18313	71	22	antibodies	antibody	NOUN
ajst-18313	71	23	,	,	PUNCT
ajst-18313	71	24	but	but	CCONJ
ajst-18313	71	25	it	it	PRON
ajst-18313	71	26	is	be	AUX
ajst-18313	71	27	not	not	PART
ajst-18313	71	28	all	all	PRON
ajst-18313	71	29	stable	stable	ADJ
ajst-18313	72	1	[	[	X
ajst-18313	72	2	12	12	NUM
ajst-18313	72	3	]	]	PUNCT
ajst-18313	72	4	.	.	PUNCT
ajst-18313	73	1	previous	previous	ADJ
ajst-18313	73	2	studies	study	NOUN
ajst-18313	73	3	have	have	AUX
ajst-18313	73	4	found	find	VERB
ajst-18313	73	5	that	that	SCONJ
ajst-18313	73	6	at	at	ADP
ajst-18313	73	7	65	65	NUM
ajst-18313	73	8	°	°	NOUN
ajst-18313	73	9	c	c	X
ajst-18313	73	10	,	,	PUNCT
ajst-18313	73	11	about	about	ADP
ajst-18313	73	12	twothirds	twothird	NOUN
ajst-18313	73	13	of	of	ADP
ajst-18313	73	14	people	people	NOUN
ajst-18313	73	15	produce	produce	VERB
ajst-18313	73	16	irreversible	irreversible	ADJ
ajst-18313	73	17	agglomeration	agglomeration	NOUN
ajst-18313	73	18	,	,	PUNCT
ajst-18313	73	19	while	while	SCONJ
ajst-18313	73	20	others	other	NOUN
ajst-18313	73	21	remain	remain	VERB
ajst-18313	73	22	more	more	ADJ
ajst-18313	73	23	than	than	ADP
ajst-18313	73	24	90	90	NUM
ajst-18313	73	25	%	%	NOUN
ajst-18313	73	26	active	active	ADJ
ajst-18313	73	27	after	after	ADP
ajst-18313	73	28	heat	heat	NOUN
ajst-18313	73	29	treatment	treatment	NOUN
ajst-18313	73	30	at	at	ADP
ajst-18313	73	31	90	90	NUM
ajst-18313	73	32	°	°	PROPN
ajst-18313	73	33	c.	c.	NOUN
ajst-18313	73	34	its	its	PRON
ajst-18313	73	35	essence	essence	NOUN
ajst-18313	73	36	is	be	AUX
ajst-18313	73	37	due	due	ADJ
ajst-18313	73	38	to	to	ADP
ajst-18313	73	39	its	its	PRON
ajst-18313	73	40	unique	unique	ADJ
ajst-18313	73	41	amino	amino	NOUN
ajst-18313	73	42	acid	acid	NOUN
ajst-18313	73	43	sequence	sequence	NOUN
ajst-18313	73	44	,	,	PUNCT
ajst-18313	73	45	the	the	DET
ajst-18313	73	46	number	number	NOUN
ajst-18313	73	47	and	and	CCONJ
ajst-18313	73	48	location	location	NOUN
ajst-18313	73	49	of	of	ADP
ajst-18313	73	50	disulfide	disulfide	NOUN
ajst-18313	73	51	bonds	bond	NOUN
ajst-18313	73	52	and	and	CCONJ
ajst-18313	73	53	the	the	DET
ajst-18313	73	54	spatial	spatial	ADJ
ajst-18313	73	55	configuration	configuration	NOUN
ajst-18313	73	56	of	of	ADP
ajst-18313	73	57	its	its	PRON
ajst-18313	73	58	domain	domain	NOUN
ajst-18313	73	59	.	.	PUNCT
ajst-18313	74	1	4.1	4.1	NUM
ajst-18313	74	2	.	.	PUNCT
ajst-18313	74	3	disulfide	disulfide	NOUN
ajst-18313	74	4	bond	bond	NOUN
ajst-18313	74	5	disulfide	disulfide	NOUN
ajst-18313	74	6	bonds	bond	NOUN
ajst-18313	74	7	play	play	VERB
ajst-18313	74	8	an	an	DET
ajst-18313	74	9	important	important	ADJ
ajst-18313	74	10	role	role	NOUN
ajst-18313	74	11	in	in	ADP
ajst-18313	74	12	the	the	DET
ajst-18313	74	13	correct	correct	ADJ
ajst-18313	74	14	folding	folding	NOUN
ajst-18313	74	15	and	and	CCONJ
ajst-18313	74	16	stability	stability	NOUN
ajst-18313	74	17	of	of	ADP
ajst-18313	74	18	cellular	cellular	ADJ
ajst-18313	74	19	efflux	efflux	NOUN
ajst-18313	74	20	proteins	protein	NOUN
ajst-18313	74	21	.	.	PUNCT
ajst-18313	75	1	studies	study	NOUN
ajst-18313	75	2	have	have	AUX
ajst-18313	75	3	shown	show	VERB
ajst-18313	75	4	that	that	SCONJ
ajst-18313	75	5	the	the	DET
ajst-18313	75	6	expression	expression	NOUN
ajst-18313	75	7	of	of	ADP
ajst-18313	75	8	nano	nano	NOUN
ajst-18313	75	9	antibodies	antibody	NOUN
ajst-18313	75	10	using	use	VERB
ajst-18313	75	11	e	e	NOUN
ajst-18313	75	12	coli	coli	NOUN
ajst-18313	75	13	system	system	NOUN
ajst-18313	75	14	has	have	AUX
ajst-18313	75	15	significantly	significantly	ADV
ajst-18313	75	16	lower	low	ADJ
ajst-18313	75	17	tm	tm	NOUN
ajst-18313	75	18	in	in	ADP
ajst-18313	75	19	the	the	DET
ajst-18313	75	20	reduced	reduced	ADJ
ajst-18313	75	21	state	state	NOUN
ajst-18313	75	22	than	than	ADP
ajst-18313	75	23	in	in	ADP
ajst-18313	75	24	the	the	DET
ajst-18313	75	25	periplasmic	periplasmic	ADJ
ajst-18313	75	26	oxidation	oxidation	NOUN
ajst-18313	75	27	state	state	NOUN
ajst-18313	75	28	,	,	PUNCT
ajst-18313	75	29	and	and	CCONJ
ajst-18313	75	30	the	the	DET
ajst-18313	75	31	difference	difference	NOUN
ajst-18313	75	32	in	in	ADP
ajst-18313	75	33	their	their	PRON
ajst-18313	75	34	stability	stability	NOUN
ajst-18313	75	35	is	be	AUX
ajst-18313	75	36	closely	closely	ADV
ajst-18313	75	37	related	relate	VERB
ajst-18313	75	38	to	to	ADP
ajst-18313	75	39	the	the	DET
ajst-18313	75	40	formation	formation	NOUN
ajst-18313	75	41	of	of	ADP
ajst-18313	75	42	disulfide	disulfide	NOUN
ajst-18313	75	43	bonds	bond	NOUN
ajst-18313	75	44	[	[	X
ajst-18313	75	45	13	13	NUM
ajst-18313	75	46	]	]	PUNCT
ajst-18313	75	47	.	.	PUNCT
ajst-18313	76	1	under	under	ADP
ajst-18313	76	2	oxidation	oxidation	NOUN
ajst-18313	76	3	conditions	condition	NOUN
ajst-18313	76	4	,	,	PUNCT
ajst-18313	76	5	the	the	DET
ajst-18313	76	6	cysteine	cysteine	NOUN
ajst-18313	76	7	group	group	NOUN
ajst-18313	76	8	underwent	undergo	VERB
ajst-18313	76	9	double	double	ADJ
ajst-18313	76	10	bond	bond	NOUN
ajst-18313	76	11	oxidation	oxidation	NOUN
ajst-18313	76	12	and	and	CCONJ
ajst-18313	76	13	introduced	introduce	VERB
ajst-18313	76	14	disulfide	disulfide	NOUN
ajst-18313	76	15	bonds	bond	NOUN
ajst-18313	76	16	into	into	ADP
ajst-18313	76	17	the	the	DET
ajst-18313	76	18	polypeptide	polypeptide	NOUN
ajst-18313	76	19	,	,	PUNCT
ajst-18313	76	20	limiting	limit	VERB
ajst-18313	76	21	its	its	PRON
ajst-18313	76	22	non	non	ADJ
ajst-18313	76	23	-	-	ADJ
ajst-18313	76	24	folded	folded	ADJ
ajst-18313	76	25	state	state	NOUN
ajst-18313	76	26	and	and	CCONJ
ajst-18313	76	27	enhancing	enhance	VERB
ajst-18313	76	28	its	its	PRON
ajst-18313	76	29	mechanical	mechanical	ADJ
ajst-18313	76	30	properties	property	NOUN
ajst-18313	76	31	and	and	CCONJ
ajst-18313	76	32	conformational	conformational	ADJ
ajst-18313	76	33	stability	stability	NOUN
ajst-18313	76	34	.	.	PUNCT
ajst-18313	77	1	most	most	ADJ
ajst-18313	77	2	of	of	ADP
ajst-18313	77	3	these	these	DET
ajst-18313	77	4	systems	system	NOUN
ajst-18313	77	5	have	have	VERB
ajst-18313	77	6	one	one	NUM
ajst-18313	77	7	or	or	CCONJ
ajst-18313	77	8	more	more	ADJ
ajst-18313	77	9	disulfide	disulfide	NOUN
ajst-18313	77	10	bonds	bond	NOUN
ajst-18313	77	11	,	,	PUNCT
ajst-18313	77	12	one	one	NUM
ajst-18313	77	13	of	of	ADP
ajst-18313	77	14	which	which	PRON
ajst-18313	77	15	connects	connect	VERB
ajst-18313	77	16	fr1	fr1	PROPN
ajst-18313	77	17	(	(	PUNCT
ajst-18313	77	18	c23	c23	PROPN
ajst-18313	77	19	)	)	PUNCT
ajst-18313	77	20	to	to	ADP
ajst-18313	77	21	fr3	fr3	PROPN
ajst-18313	77	22	(	(	PUNCT
ajst-18313	77	23	c104	c104	PROPN
ajst-18313	77	24	)	)	PUNCT
ajst-18313	77	25	and	and	CCONJ
ajst-18313	77	26	the	the	DET
ajst-18313	77	27	other	other	ADJ
ajst-18313	77	28	is	be	AUX
ajst-18313	77	29	a	a	DET
ajst-18313	77	30	disulfide	disulfide	NOUN
ajst-18313	77	31	-	-	PUNCT
ajst-18313	77	32	dioxy	dioxy	ADJ
ajst-18313	77	33	disulfide	disulfide	NOUN
ajst-18313	77	34	bond	bond	NOUN
ajst-18313	77	35	that	that	PRON
ajst-18313	77	36	connects	connect	VERB
ajst-18313	77	37	cdr3	cdr3	ADJ
ajst-18313	77	38	to	to	ADP
ajst-18313	77	39	other	other	ADJ
ajst-18313	77	40	functional	functional	ADJ
ajst-18313	77	41	regions	region	NOUN
ajst-18313	77	42	.	.	PUNCT
ajst-18313	78	1	the	the	DET
ajst-18313	78	2	additional	additional	ADJ
ajst-18313	78	3	disulfide	disulfide	NOUN
ajst-18313	78	4	bonds	bond	NOUN
ajst-18313	78	5	are	be	AUX
ajst-18313	78	6	arranged	arrange	VERB
ajst-18313	78	7	according	accord	VERB
ajst-18313	78	8	to	to	ADP
ajst-18313	78	9	the	the	DET
ajst-18313	78	10	annular	annular	ADJ
ajst-18313	78	11	disulfide	disulfide	NOUN
ajst-18313	78	12	bond	bond	NOUN
ajst-18313	78	13	between	between	ADP
ajst-18313	78	14	cdr3	cdr3	PROPN
ajst-18313	78	15	and	and	CCONJ
ajst-18313	78	16	cdr1	cdr1	PROPN
ajst-18313	78	17	or	or	CCONJ
ajst-18313	78	18	between	between	ADP
ajst-18313	78	19	cdr2	cdr2	PROPN
ajst-18313	78	20	/	/	SYM
ajst-18313	78	21	fr2	fr2	PROPN
ajst-18313	78	22	and	and	CCONJ
ajst-18313	78	23	the	the	DET
ajst-18313	78	24	internal	internal	ADJ
ajst-18313	78	25	disulfide	disulfide	NOUN
ajst-18313	78	26	bond	bond	NOUN
ajst-18313	78	27	of	of	ADP
ajst-18313	78	28	cdr3	cdr3	PROPN
ajst-18313	78	29	(	(	PUNCT
ajst-18313	78	30	figure	figure	NOUN
ajst-18313	78	31	3	3	NUM
ajst-18313	78	32	cited	cite	VERB
ajst-18313	78	33	in	in	ADP
ajst-18313	78	34	the	the	DET
ajst-18313	78	35	general	general	ADJ
ajst-18313	78	36	synthetic	synthetic	ADJ
ajst-18313	78	37	strategy	strategy	NOUN
ajst-18313	78	38	for	for	ADP
ajst-18313	78	39	regioselective	regioselective	ADJ
ajst-18313	78	40	ultrafast	ultrafast	NOUN
ajst-18313	78	41	)	)	PUNCT
ajst-18313	78	42	formation	formation	NOUN
ajst-18313	78	43	of	of	ADP
ajst-18313	78	44	disulfide	disulfide	NOUN
ajst-18313	78	45	bonds	bond	NOUN
ajst-18313	78	46	in	in	ADP
ajst-18313	78	47	peptides	peptide	NOUN
ajst-18313	78	48	and	and	CCONJ
ajst-18313	78	49	proteins	protein	NOUN
ajst-18313	78	50	)	)	PUNCT
ajst-18313	78	51	.	.	PUNCT
ajst-18313	79	1	figure	figure	VERB
ajst-18313	79	2	3	3	NUM
ajst-18313	79	3	.	.	NOUN
ajst-18313	79	4	three	three	NUM
ajst-18313	79	5	different	different	ADJ
ajst-18313	79	6	types	type	NOUN
ajst-18313	79	7	of	of	ADP
ajst-18313	79	8	additional	additional	ADJ
ajst-18313	79	9	disulfide	disulfide	NOUN
ajst-18313	79	10	bonds	bond	NOUN
ajst-18313	79	11	in	in	ADP
ajst-18313	79	12	nanoantibodies	nanoantibodie	NOUN
ajst-18313	79	13	the	the	DET
ajst-18313	79	14	cysteine	cysteine	NOUN
ajst-18313	79	15	in	in	ADP
ajst-18313	79	16	cdr1,fr2,cdr2	cdr1,fr2,cdr2	PROPN
ajst-18313	79	17	and	and	CCONJ
ajst-18313	79	18	other	other	ADJ
ajst-18313	79	19	regions	region	NOUN
ajst-18313	79	20	is	be	AUX
ajst-18313	79	21	usually	usually	ADV
ajst-18313	79	22	located	locate	VERB
ajst-18313	79	23	in	in	ADP
ajst-18313	79	24	conserved	conserved	ADJ
ajst-18313	79	25	sites	site	NOUN
ajst-18313	79	26	,	,	PUNCT
ajst-18313	79	27	while	while	SCONJ
ajst-18313	79	28	the	the	DET
ajst-18313	79	29	cysteine	cysteine	NOUN
ajst-18313	79	30	in	in	ADP
ajst-18313	79	31	cdr3	cdr3	PROPN
ajst-18313	79	32	is	be	AUX
ajst-18313	79	33	randomly	randomly	ADV
ajst-18313	79	34	distributed	distribute	VERB
ajst-18313	79	35	,	,	PUNCT
ajst-18313	79	36	because	because	SCONJ
ajst-18313	79	37	the	the	DET
ajst-18313	79	38	cysteine	cysteine	NOUN
ajst-18313	79	39	in	in	ADP
ajst-18313	79	40	cdr3	cdr3	PROPN
ajst-18313	79	41	is	be	AUX
ajst-18313	79	42	encoded	encode	VERB
ajst-18313	79	43	by	by	ADP
ajst-18313	79	44	the	the	DET
ajst-18313	79	45	reproductive	reproductive	ADJ
ajst-18313	79	46	gene	gene	NOUN
ajst-18313	79	47	,	,	PUNCT
ajst-18313	79	48	and	and	CCONJ
ajst-18313	79	49	the	the	DET
ajst-18313	79	50	second	second	ADJ
ajst-18313	79	51	cysteine	cysteine	NOUN
ajst-18313	79	52	site	site	NOUN
ajst-18313	79	53	in	in	ADP
ajst-18313	79	54	cdr3	cdr3	PROPN
ajst-18313	79	55	occurs	occur	VERB
ajst-18313	79	56	before	before	ADV
ajst-18313	79	57	and	and	CCONJ
ajst-18313	79	58	after	after	ADP
ajst-18313	79	59	the	the	DET
ajst-18313	79	60	v	v	NOUN
ajst-18313	79	61	-	-	PUNCT
ajst-18313	79	62	d	d	NOUN
ajst-18313	79	63	-	-	PROPN
ajst-18313	79	64	j	j	PROPN
ajst-18313	79	65	rearrangement	rearrangement	NOUN
ajst-18313	80	1	[	[	X
ajst-18313	80	2	14	14	NUM
ajst-18313	80	3	]	]	PUNCT
ajst-18313	80	4	.	.	PUNCT
ajst-18313	81	1	through	through	ADP
ajst-18313	81	2	the	the	DET
ajst-18313	81	3	study	study	NOUN
ajst-18313	81	4	of	of	ADP
ajst-18313	81	5	their	their	PRON
ajst-18313	81	6	sequencing	sequence	VERB
ajst-18313	81	7	data	datum	NOUN
ajst-18313	81	8	,	,	PUNCT
ajst-18313	81	9	in	in	ADP
ajst-18313	81	10	the	the	DET
ajst-18313	81	11	nanoantibodies	nanoantibodie	NOUN
ajst-18313	81	12	,	,	PUNCT
ajst-18313	81	13	cysteine	cysteine	NOUN
ajst-18313	81	14	residues	residue	NOUN
ajst-18313	81	15	are	be	AUX
ajst-18313	81	16	usually	usually	ADV
ajst-18313	81	17	present	present	ADJ
ajst-18313	81	18	in	in	ADP
ajst-18313	81	19	pairs	pair	NOUN
ajst-18313	81	20	,	,	PUNCT
ajst-18313	81	21	and	and	CCONJ
ajst-18313	81	22	this	this	DET
ajst-18313	81	23	phenomenon	phenomenon	NOUN
ajst-18313	81	24	is	be	AUX
ajst-18313	81	25	mainly	mainly	ADV
ajst-18313	81	26	due	due	ADP
ajst-18313	81	27	to	to	ADP
ajst-18313	81	28	its	its	PRON
ajst-18313	81	29	active	active	ADJ
ajst-18313	81	30	screening	screening	NOUN
ajst-18313	81	31	during	during	ADP
ajst-18313	81	32	the	the	DET
ajst-18313	81	33	development	development	NOUN
ajst-18313	81	34	of	of	ADP
ajst-18313	81	35	b	b	NOUN
ajst-18313	81	36	cells	cell	NOUN
ajst-18313	81	37	.	.	PUNCT
ajst-18313	82	1	the	the	DET
ajst-18313	82	2	nano	nano	NOUN
ajst-18313	82	3	antibodies	antibodie	VERB
ajst-18313	82	4	12	12	NUM
ajst-18313	82	5	containing	contain	VERB
ajst-18313	82	6	terminal	terminal	ADJ
ajst-18313	82	7	double	double	ADJ
ajst-18313	82	8	-	-	PUNCT
ajst-18313	82	9	chain	chain	NOUN
ajst-18313	82	10	cysteine	cysteine	NOUN
ajst-18313	82	11	are	be	AUX
ajst-18313	82	12	easily	easily	ADV
ajst-18313	82	13	oxidized	oxidize	VERB
ajst-18313	82	14	,	,	PUNCT
ajst-18313	82	15	which	which	PRON
ajst-18313	82	16	makes	make	VERB
ajst-18313	82	17	them	they	PRON
ajst-18313	82	18	lose	lose	VERB
ajst-18313	82	19	the	the	DET
ajst-18313	82	20	binding	binding	NOUN
ajst-18313	82	21	with	with	ADP
ajst-18313	82	22	antigen	antigen	PROPN
ajst-18313	82	23	,	,	PUNCT
ajst-18313	82	24	and	and	CCONJ
ajst-18313	82	25	are	be	AUX
ajst-18313	82	26	prone	prone	ADJ
ajst-18313	82	27	to	to	ADP
ajst-18313	82	28	dimerization	dimerization	NOUN
ajst-18313	82	29	during	during	ADP
ajst-18313	82	30	the	the	DET
ajst-18313	82	31	preservation	preservation	NOUN
ajst-18313	82	32	process	process	NOUN
ajst-18313	82	33	due	due	ADP
ajst-18313	82	34	to	to	ADP
ajst-18313	82	35	long	long	ADJ
ajst-18313	82	36	-	-	PUNCT
ajst-18313	82	37	term	term	NOUN
ajst-18313	82	38	preservation	preservation	NOUN
ajst-18313	82	39	.	.	PUNCT
ajst-18313	83	1	however	however	ADV
ajst-18313	83	2	,	,	PUNCT
ajst-18313	83	3	there	there	PRON
ajst-18313	83	4	is	be	VERB
ajst-18313	83	5	also	also	ADV
ajst-18313	83	6	a	a	DET
ajst-18313	83	7	new	new	ADJ
ajst-18313	83	8	class	class	NOUN
ajst-18313	83	9	of	of	ADP
ajst-18313	83	10	cysteine	cysteine	NOUN
ajst-18313	83	11	roots	root	NOUN
ajst-18313	83	12	,	,	PUNCT
ajst-18313	83	13	that	that	ADV
ajst-18313	83	14	is	is	ADV
ajst-18313	83	15	,	,	PUNCT
ajst-18313	83	16	a	a	DET
ajst-18313	83	17	new	new	ADJ
ajst-18313	83	18	cysteine	cysteine	NOUN
ajst-18313	83	19	root	root	NOUN
ajst-18313	83	20	,	,	PUNCT
ajst-18313	83	21	which	which	PRON
ajst-18313	83	22	has	have	VERB
ajst-18313	83	23	a	a	DET
ajst-18313	83	24	coordination	coordination	NOUN
ajst-18313	83	25	relationship	relationship	NOUN
ajst-18313	83	26	with	with	ADP
ajst-18313	83	27	three	three	NUM
ajst-18313	83	28	other	other	ADJ
ajst-18313	83	29	amino	amino	ADJ
ajst-18313	83	30	acids	acid	NOUN
ajst-18313	83	31	,	,	PUNCT
ajst-18313	83	32	and	and	CCONJ
ajst-18313	83	33	uses	use	VERB
ajst-18313	83	34	zinc	zinc	NOUN
ajst-18313	83	35	instead	instead	ADV
ajst-18313	83	36	of	of	ADP
ajst-18313	83	37	disulfide	disulfide	NOUN
ajst-18313	83	38	bonds	bond	NOUN
ajst-18313	83	39	as	as	ADP
ajst-18313	83	40	a	a	DET
ajst-18313	83	41	bridge	bridge	NOUN
ajst-18313	83	42	connecting	connect	VERB
ajst-18313	83	43	the	the	DET
ajst-18313	83	44	cdr1	cdr1	PROPN
ajst-18313	83	45	and	and	CCONJ
ajst-18313	83	46	cdr3	cdr3	ADJ
ajst-18313	83	47	ring	ring	NOUN
ajst-18313	83	48	configurations	configuration	NOUN
ajst-18313	83	49	,	,	PUNCT
ajst-18313	83	50	enhancing	enhance	VERB
ajst-18313	83	51	the	the	DET
ajst-18313	83	52	rigidity	rigidity	NOUN
ajst-18313	83	53	of	of	ADP
ajst-18313	83	54	the	the	DET
ajst-18313	83	55	cdr3	cdr3	ADJ
ajst-18313	83	56	ring	ring	NOUN
ajst-18313	83	57	configurations	configuration	NOUN
ajst-18313	83	58	.	.	PUNCT
ajst-18313	84	1	4.2	4.2	NUM
ajst-18313	84	2	.	.	PUNCT
ajst-18313	85	1	domain	domain	NOUN
ajst-18313	85	2	cdrs	cdr	NOUN
ajst-18313	85	3	affect	affect	VERB
ajst-18313	85	4	their	their	PRON
ajst-18313	85	5	ability	ability	NOUN
ajst-18313	85	6	to	to	PART
ajst-18313	85	7	bind	bind	VERB
ajst-18313	85	8	to	to	ADP
ajst-18313	85	9	the	the	DET
ajst-18313	85	10	target	target	NOUN
ajst-18313	85	11	at	at	ADP
ajst-18313	85	12	the	the	DET
ajst-18313	85	13	molecular	molecular	ADJ
ajst-18313	85	14	level	level	NOUN
ajst-18313	85	15	,	,	PUNCT
ajst-18313	85	16	and	and	CCONJ
ajst-18313	85	17	their	their	PRON
ajst-18313	85	18	stability	stability	NOUN
ajst-18313	85	19	under	under	ADP
ajst-18313	85	20	chemical	chemical	NOUN
ajst-18313	85	21	denaturants	denaturant	NOUN
ajst-18313	85	22	,	,	PUNCT
ajst-18313	85	23	temperatures	temperature	NOUN
ajst-18313	85	24	,	,	PUNCT
ajst-18313	85	25	proteases	protease	NOUN
ajst-18313	85	26	,	,	PUNCT
ajst-18313	85	27	and	and	CCONJ
ajst-18313	85	28	extreme	extreme	ADJ
ajst-18313	85	29	ph	ph	NOUN
ajst-18313	85	30	depends	depend	VERB
ajst-18313	85	31	on	on	ADP
ajst-18313	85	32	amino	amino	NOUN
ajst-18313	85	33	acid	acid	NOUN
ajst-18313	85	34	residues	residue	NOUN
ajst-18313	85	35	.	.	PUNCT
ajst-18313	86	1	in	in	ADP
ajst-18313	86	2	conventional	conventional	ADJ
ajst-18313	86	3	antibody	antibody	NOUN
ajst-18313	86	4	structure	structure	NOUN
ajst-18313	86	5	,	,	PUNCT
ajst-18313	86	6	there	there	PRON
ajst-18313	86	7	are	be	VERB
ajst-18313	86	8	multiple	multiple	ADJ
ajst-18313	86	9	on	on	ADP
ajst-18313	86	10	fr	fr	ADJ
ajst-18313	86	11	hydrophobic	hydrophobic	NOUN
ajst-18313	86	12	residues	residue	NOUN
ajst-18313	86	13	(	(	PUNCT
ajst-18313	86	14	l12	l12	NOUN
ajst-18313	86	15	,	,	PUNCT
ajst-18313	86	16	v42	v42	NOUN
ajst-18313	86	17	g49	g49	PROPN
ajst-18313	86	18	,	,	PUNCT
ajst-18313	86	19	l50	l50	NOUN
ajst-18313	86	20	,	,	PUNCT
ajst-18313	86	21	w52	w52	NOUN
ajst-18313	86	22	,	,	PUNCT
ajst-18313	86	23	foundry	foundry	NOUN
ajst-18313	86	24	shops	shop	NOUN
ajst-18313	86	25	,	,	PUNCT
ajst-18313	86	26	w117	w117	NUM
ajst-18313	86	27	)	)	PUNCT
ajst-18313	86	28	,	,	PUNCT
ajst-18313	86	29	participated	participate	VERB
ajst-18313	86	30	in	in	ADP
ajst-18313	86	31	the	the	DET
ajst-18313	86	32	heavy	heavy	ADJ
ajst-18313	86	33	chain	chain	NOUN
ajst-18313	86	34	links	link	NOUN
ajst-18313	86	35	with	with	ADP
ajst-18313	86	36	ch	ch	NOUN
ajst-18313	86	37	and	and	CCONJ
ajst-18313	86	38	light	light	ADJ
ajst-18313	86	39	chain	chain	NOUN
ajst-18313	86	40	.	.	PUNCT
ajst-18313	87	1	but	but	CCONJ
ajst-18313	87	2	if	if	SCONJ
ajst-18313	87	3	it	it	PRON
ajst-18313	87	4	exceeds	exceed	VERB
ajst-18313	87	5	tm	tm	PROPN
ajst-18313	87	6	,	,	PUNCT
ajst-18313	87	7	this	this	DET
ajst-18313	87	8	hydrophobic	hydrophobic	NOUN
ajst-18313	87	9	surface	surface	NOUN
ajst-18313	87	10	will	will	AUX
ajst-18313	87	11	be	be	AUX
ajst-18313	87	12	broken	break	VERB
ajst-18313	87	13	down	down	ADP
ajst-18313	87	14	by	by	ADP
ajst-18313	87	15	conventional	conventional	ADJ
ajst-18313	87	16	antibodies	antibody	NOUN
ajst-18313	87	17	,	,	PUNCT
ajst-18313	87	18	resulting	result	VERB
ajst-18313	87	19	in	in	ADP
ajst-18313	87	20	intermolecular	intermolecular	ADJ
ajst-18313	87	21	interactions	interaction	NOUN
ajst-18313	87	22	that	that	PRON
ajst-18313	87	23	cause	cause	VERB
ajst-18313	87	24	non	non	ADJ
ajst-18313	87	25	-	-	ADJ
ajst-18313	87	26	specific	specific	ADJ
ajst-18313	87	27	aggregation	aggregation	NOUN
ajst-18313	87	28	and	and	CCONJ
ajst-18313	87	29	deposition	deposition	NOUN
ajst-18313	87	30	.	.	PUNCT
ajst-18313	88	1	in	in	ADP
ajst-18313	88	2	the	the	DET
ajst-18313	88	3	preparation	preparation	NOUN
ajst-18313	88	4	process	process	NOUN
ajst-18313	88	5	,	,	PUNCT
ajst-18313	88	6	due	due	ADP
ajst-18313	88	7	to	to	ADP
ajst-18313	88	8	its	its	PRON
ajst-18313	88	9	own	own	ADJ
ajst-18313	88	10	high	high	ADJ
ajst-18313	88	11	solubility	solubility	NOUN
ajst-18313	88	12	,	,	PUNCT
ajst-18313	88	13	it	it	PRON
ajst-18313	88	14	must	must	AUX
ajst-18313	88	15	be	be	AUX
ajst-18313	88	16	folded	fold	VERB
ajst-18313	88	17	with	with	ADP
ajst-18313	88	18	the	the	DET
ajst-18313	88	19	help	help	NOUN
ajst-18313	88	20	of	of	ADP
ajst-18313	88	21	proteins	protein	NOUN
ajst-18313	88	22	in	in	ADP
ajst-18313	88	23	the	the	DET
ajst-18313	88	24	self	self	NOUN
ajst-18313	88	25	-	-	PUNCT
ajst-18313	88	26	assembly	assembly	NOUN
ajst-18313	88	27	process	process	NOUN
ajst-18313	88	28	.	.	PUNCT
ajst-18313	89	1	in	in	ADP
ajst-18313	89	2	camels	camel	NOUN
ajst-18313	89	3	,	,	PUNCT
ajst-18313	89	4	in	in	ADP
ajst-18313	89	5	order	order	NOUN
ajst-18313	89	6	to	to	PART
ajst-18313	89	7	avoid	avoid	VERB
ajst-18313	89	8	heavy	heavy	ADJ
ajst-18313	89	9	chain	chain	NOUN
ajst-18313	89	10	polymerization	polymerization	NOUN
ajst-18313	89	11	,	,	PUNCT
ajst-18313	89	12	some	some	DET
ajst-18313	89	13	amino	amino	ADJ
ajst-18313	89	14	acids	acid	NOUN
ajst-18313	89	15	are	be	AUX
ajst-18313	89	16	mutated	mutate	VERB
ajst-18313	89	17	,	,	PUNCT
ajst-18313	89	18	some	some	DET
ajst-18313	89	19	amino	amino	ADJ
ajst-18313	89	20	acids	acid	NOUN
ajst-18313	89	21	are	be	AUX
ajst-18313	89	22	enhanced	enhance	VERB
ajst-18313	89	23	by	by	ADP
ajst-18313	89	24	hydrophilicity	hydrophilicity	NOUN
ajst-18313	89	25	,	,	PUNCT
ajst-18313	89	26	and	and	CCONJ
ajst-18313	89	27	some	some	DET
ajst-18313	89	28	amino	amino	ADJ
ajst-18313	89	29	acids	acid	NOUN
ajst-18313	89	30	are	be	AUX
ajst-18313	89	31	surrounded	surround	VERB
ajst-18313	89	32	by	by	ADP
ajst-18313	89	33	cdr3	cdr3	ADJ
ajst-18313	89	34	,	,	PUNCT
ajst-18313	89	35	making	make	VERB
ajst-18313	89	36	them	they	PRON
ajst-18313	89	37	insoluble	insoluble	ADJ
ajst-18313	89	38	in	in	ADP
ajst-18313	89	39	solution	solution	NOUN
ajst-18313	89	40	.	.	PUNCT
ajst-18313	90	1	in	in	ADP
ajst-18313	90	2	particular	particular	ADJ
ajst-18313	90	3	,	,	PUNCT
ajst-18313	90	4	on	on	ADP
ajst-18313	90	5	vh	vh	PROPN
ajst-18313	90	6	,	,	PUNCT
ajst-18313	90	7	v~	v~	PROPN
ajst-18313	90	8	f	f	PROPN
ajst-18313	90	9	can	can	AUX
ajst-18313	90	10	fill	fill	VERB
ajst-18313	90	11	the	the	DET
ajst-18313	90	12	hydrophobic	hydrophobic	NOUN
ajst-18313	90	13	region	region	NOUN
ajst-18313	90	14	composed	compose	VERB
ajst-18313	90	15	of	of	ADP
ajst-18313	90	16	y95,w117,cdr3	y95,w117,cdr3	NOUN
ajst-18313	90	17	and	and	CCONJ
ajst-18313	90	18	other	other	ADJ
ajst-18313	90	19	side	side	NOUN
ajst-18313	90	20	chains	chain	NOUN
ajst-18313	90	21	,	,	PUNCT
ajst-18313	90	22	while	while	SCONJ
ajst-18313	90	23	on	on	ADP
ajst-18313	90	24	w117r	w117r	PROPN
ajst-18313	90	25	,	,	PUNCT
ajst-18313	90	26	larger	large	ADJ
ajst-18313	90	27	side	side	NOUN
ajst-18313	90	28	chains	chain	NOUN
ajst-18313	90	29	of	of	ADP
ajst-18313	90	30	f42	f42	PROPN
ajst-18313	90	31	can	can	AUX
ajst-18313	90	32	migrate	migrate	VERB
ajst-18313	90	33	to	to	ADP
ajst-18313	90	34	y95	y95	NOUN
ajst-18313	90	35	and	and	CCONJ
ajst-18313	90	36	r117	r117	NUM
ajst-18313	90	37	,	,	PUNCT
ajst-18313	90	38	strengthening	strengthen	VERB
ajst-18313	90	39	the	the	DET
ajst-18313	90	40	hydrophobic	hydrophobic	NOUN
ajst-18313	90	41	stacking	stacking	NOUN
ajst-18313	90	42	between	between	ADP
ajst-18313	90	43	molecules	molecule	NOUN
ajst-18313	90	44	and	and	CCONJ
ajst-18313	90	45	improving	improve	VERB
ajst-18313	90	46	the	the	DET
ajst-18313	90	47	stability	stability	NOUN
ajst-18313	90	48	of	of	ADP
ajst-18313	90	49	the	the	DET
ajst-18313	90	50	structure	structure	NOUN
ajst-18313	90	51	.	.	PUNCT
ajst-18313	91	1	in	in	ADP
ajst-18313	91	2	addition	addition	NOUN
ajst-18313	91	3	,	,	PUNCT
ajst-18313	91	4	the	the	DET
ajst-18313	91	5	v	v	NOUN
ajst-18313	91	6	and	and	CCONJ
ajst-18313	91	7	e	e	NOUN
ajst-18313	91	8	residues	residue	NOUN
ajst-18313	91	9	of	of	ADP
ajst-18313	91	10	fr1	fr1	PROPN
ajst-18313	91	11	are	be	AUX
ajst-18313	91	12	amino	amino	ADJ
ajst-18313	91	13	acids	acid	NOUN
ajst-18313	91	14	common	common	ADJ
ajst-18313	91	15	to	to	ADP
ajst-18313	91	16	many	many	ADJ
ajst-18313	91	17	structurally	structurally	ADV
ajst-18313	91	18	stable	stable	ADJ
ajst-18313	91	19	nanoantibodies	nanoantibodie	NOUN
ajst-18313	91	20	,	,	PUNCT
ajst-18313	91	21	and	and	CCONJ
ajst-18313	91	22	are	be	AUX
ajst-18313	91	23	also	also	ADV
ajst-18313	91	24	common	common	ADJ
ajst-18313	91	25	sites	site	NOUN
ajst-18313	91	26	for	for	ADP
ajst-18313	91	27	inducing	induce	VERB
ajst-18313	91	28	genetic	genetic	ADJ
ajst-18313	91	29	engineering	engineering	NOUN
ajst-18313	91	30	modification	modification	NOUN
ajst-18313	91	31	.	.	PUNCT
ajst-18313	92	1	5	5	X
ajst-18313	92	2	.	.	X
ajst-18313	92	3	conclusion	conclusion	NOUN
ajst-18313	92	4	although	although	SCONJ
ajst-18313	92	5	many	many	ADJ
ajst-18313	92	6	scholars	scholar	NOUN
ajst-18313	92	7	have	have	AUX
ajst-18313	92	8	obtained	obtain	VERB
ajst-18313	92	9	nano	nano	NOUN
ajst-18313	92	10	-	-	PUNCT
ajst-18313	92	11	antibodies	antibody	NOUN
ajst-18313	92	12	with	with	ADP
ajst-18313	92	13	high	high	ADJ
ajst-18313	92	14	stability	stability	NOUN
ajst-18313	92	15	by	by	ADP
ajst-18313	92	16	site	site	NOUN
ajst-18313	92	17	-	-	PUNCT
ajst-18313	92	18	specific	specific	ADJ
ajst-18313	92	19	mutation	mutation	NOUN
ajst-18313	92	20	and	and	CCONJ
ajst-18313	92	21	modification	modification	NOUN
ajst-18313	92	22	of	of	ADP
ajst-18313	92	23	single	single	ADJ
ajst-18313	92	24	sulfur	sulfur	NOUN
ajst-18313	92	25	bond	bond	NOUN
ajst-18313	92	26	,	,	PUNCT
ajst-18313	92	27	these	these	DET
ajst-18313	92	28	modifications	modification	NOUN
ajst-18313	92	29	are	be	AUX
ajst-18313	92	30	based	base	VERB
ajst-18313	92	31	on	on	ADP
ajst-18313	92	32	common	common	ADJ
ajst-18313	92	33	sequence	sequence	NOUN
ajst-18313	92	34	and	and	CCONJ
ajst-18313	92	35	empirical	empirical	ADJ
ajst-18313	92	36	data	datum	NOUN
ajst-18313	92	37	,	,	PUNCT
ajst-18313	92	38	and	and	CCONJ
ajst-18313	92	39	the	the	DET
ajst-18313	92	40	analysis	analysis	NOUN
ajst-18313	92	41	of	of	ADP
ajst-18313	92	42	their	their	PRON
ajst-18313	92	43	stability	stability	NOUN
ajst-18313	92	44	is	be	AUX
ajst-18313	92	45	very	very	ADV
ajst-18313	92	46	few	few	ADJ
ajst-18313	92	47	,	,	PUNCT
ajst-18313	92	48	resulting	result	VERB
ajst-18313	92	49	in	in	ADP
ajst-18313	92	50	limitations	limitation	NOUN
ajst-18313	92	51	in	in	ADP
ajst-18313	92	52	stability	stability	NOUN
ajst-18313	92	53	studies	study	NOUN
ajst-18313	92	54	.	.	PUNCT
ajst-18313	93	1	the	the	DET
ajst-18313	93	2	synthesis	synthesis	NOUN
ajst-18313	93	3	and	and	CCONJ
ajst-18313	93	4	structure	structure	NOUN
ajst-18313	93	5	analysis	analysis	NOUN
ajst-18313	93	6	of	of	ADP
ajst-18313	93	7	protein	protein	NOUN
ajst-18313	93	8	crystals	crystal	NOUN
ajst-18313	93	9	are	be	AUX
ajst-18313	93	10	the	the	DET
ajst-18313	93	11	most	most	ADV
ajst-18313	93	12	intuitive	intuitive	ADJ
ajst-18313	93	13	and	and	CCONJ
ajst-18313	93	14	accurate	accurate	ADJ
ajst-18313	93	15	means	mean	NOUN
ajst-18313	93	16	to	to	PART
ajst-18313	93	17	study	study	VERB
ajst-18313	93	18	protein	protein	NOUN
ajst-18313	93	19	structure	structure	NOUN
ajst-18313	93	20	,	,	PUNCT
ajst-18313	93	21	which	which	PRON
ajst-18313	93	22	can	can	AUX
ajst-18313	93	23	reveal	reveal	VERB
ajst-18313	93	24	the	the	DET
ajst-18313	93	25	essence	essence	NOUN
ajst-18313	93	26	of	of	ADP
ajst-18313	93	27	protein	protein	NOUN
ajst-18313	93	28	structure	structure	NOUN
ajst-18313	93	29	from	from	ADP
ajst-18313	93	30	the	the	DET
ajst-18313	93	31	molecular	molecular	ADJ
ajst-18313	93	32	level	level	NOUN
ajst-18313	93	33	.	.	PUNCT
ajst-18313	94	1	this	this	DET
ajst-18313	94	2	project	project	NOUN
ajst-18313	94	3	intends	intend	VERB
ajst-18313	94	4	to	to	PART
ajst-18313	94	5	construct	construct	VERB
ajst-18313	94	6	a	a	DET
ajst-18313	94	7	spatial	spatial	ADJ
ajst-18313	94	8	structure	structure	NOUN
ajst-18313	94	9	model	model	NOUN
ajst-18313	94	10	of	of	ADP
ajst-18313	94	11	the	the	DET
ajst-18313	94	12	interaction	interaction	NOUN
ajst-18313	94	13	between	between	ADP
ajst-18313	94	14	a	a	DET
ajst-18313	94	15	novel	novel	ADJ
ajst-18313	94	16	nanoantibody	nanoantibody	NOUN
ajst-18313	94	17	and	and	CCONJ
ajst-18313	94	18	prokaryotes	prokaryote	NOUN
ajst-18313	94	19	by	by	ADP
ajst-18313	94	20	using	use	VERB
ajst-18313	94	21	methods	method	NOUN
ajst-18313	94	22	such	such	ADJ
ajst-18313	94	23	as	as	ADP
ajst-18313	94	24	protein	protein	NOUN
ajst-18313	94	25	crystallization	crystallization	NOUN
ajst-18313	94	26	,	,	PUNCT
ajst-18313	94	27	crystal	crystal	NOUN
ajst-18313	94	28	structure	structure	NOUN
ajst-18313	94	29	analysis	analysis	NOUN
ajst-18313	94	30	and	and	CCONJ
ajst-18313	94	31	molecular	molecular	ADJ
ajst-18313	94	32	dynamics	dynamic	NOUN
ajst-18313	94	33	,	,	PUNCT
ajst-18313	94	34	and	and	CCONJ
ajst-18313	94	35	clarify	clarify	VERB
ajst-18313	94	36	key	key	ADJ
ajst-18313	94	37	factors	factor	NOUN
ajst-18313	94	38	such	such	ADJ
ajst-18313	94	39	as	as	ADP
ajst-18313	94	40	its	its	PRON
ajst-18313	94	41	recognition	recognition	NOUN
ajst-18313	94	42	mode	mode	NOUN
ajst-18313	94	43	,	,	PUNCT
ajst-18313	94	44	key	key	ADJ
ajst-18313	94	45	amino	amino	NOUN
ajst-18313	94	46	acid	acid	NOUN
ajst-18313	94	47	residues	residue	NOUN
ajst-18313	94	48	,	,	PUNCT
ajst-18313	94	49	binding	bind	VERB
ajst-18313	94	50	sites	site	NOUN
ajst-18313	94	51	and	and	CCONJ
ajst-18313	94	52	force	force	NOUN
ajst-18313	94	53	types	type	NOUN
ajst-18313	94	54	.	.	PUNCT
ajst-18313	95	1	the	the	DET
ajst-18313	95	2	influence	influence	NOUN
ajst-18313	95	3	mechanism	mechanism	NOUN
ajst-18313	95	4	of	of	ADP
ajst-18313	95	5	first	first	ADJ
ajst-18313	95	6	-	-	PUNCT
ajst-18313	95	7	order	order	NOUN
ajst-18313	95	8	sequence	sequence	NOUN
ajst-18313	95	9	,	,	PUNCT
ajst-18313	95	10	second	second	ADJ
ajst-18313	95	11	-	-	PUNCT
ajst-18313	95	12	order	order	NOUN
ajst-18313	95	13	folding	folding	NOUN
ajst-18313	95	14	and	and	CCONJ
ajst-18313	95	15	third	third	ADJ
ajst-18313	95	16	-	-	PUNCT
ajst-18313	95	17	order	order	NOUN
ajst-18313	95	18	spatial	spatial	ADJ
ajst-18313	95	19	structure	structure	NOUN
ajst-18313	95	20	on	on	ADP
ajst-18313	95	21	its	its	PRON
ajst-18313	95	22	stability	stability	NOUN
ajst-18313	95	23	was	be	AUX
ajst-18313	95	24	revealed	reveal	VERB
ajst-18313	95	25	.	.	PUNCT
ajst-18313	96	1	references	reference	NOUN
ajst-18313	96	2	[	[	X
ajst-18313	96	3	1	1	NUM
ajst-18313	96	4	]	]	X
ajst-18313	96	5	jia	jia	PROPN
ajst-18313	96	6	haijing	haijing	NOUN
ajst-18313	96	7	,	,	PUNCT
ajst-18313	96	8	gao	gao	PROPN
ajst-18313	96	9	yajing	yajing	PROPN
ajst-18313	96	10	,	,	PUNCT
ajst-18313	96	11	lou	lou	PROPN
ajst-18313	96	12	xinhui	xinhui	PROPN
ajst-18313	96	13	.	.	PUNCT
ajst-18313	97	1	the	the	DET
ajst-18313	97	2	main	main	ADJ
ajst-18313	97	3	research	research	NOUN
ajst-18313	97	4	directions	direction	NOUN
ajst-18313	97	5	,	,	PUNCT
ajst-18313	97	6	progress	progress	NOUN
ajst-18313	97	7	and	and	CCONJ
ajst-18313	97	8	challenges	challenge	NOUN
ajst-18313	97	9	of	of	ADP
ajst-18313	97	10	aptamer	aptamer	NOUN
ajst-18313	97	11	screening	screening	NOUN
ajst-18313	97	12	and	and	CCONJ
ajst-18313	97	13	affinity	affinity	NOUN
ajst-18313	97	14	evaluation	evaluation	NOUN
ajst-18313	97	15	technology	technology	NOUN
ajst-18313	97	16	.	.	PUNCT
ajst-18313	98	1	advances	advance	NOUN
ajst-18313	98	2	in	in	ADP
ajst-18313	98	3	biochemistry	biochemistry	NOUN
ajst-18313	98	4	and	and	CCONJ
ajst-18313	98	5	biophysics	biophysic	NOUN
ajst-18313	98	6	,	,	PUNCT
ajst-18313	98	7	vol	vol	NOUN
ajst-18313	98	8	.	.	PROPN
ajst-18313	98	9	50	50	NUM
ajst-18313	98	10	(	(	PUNCT
ajst-18313	98	11	2023	2023	NUM
ajst-18313	98	12	)	)	PUNCT
ajst-18313	99	1	no.9	no.9	PROPN
ajst-18313	99	2	,	,	PUNCT
ajst-18313	99	3	p.2051	p.2051	PROPN
ajst-18313	99	4	-	-	PUNCT
ajst-18313	99	5	2076	2076	NUM
ajst-18313	99	6	.	.	PUNCT
ajst-18313	100	1	[	[	X
ajst-18313	100	2	2	2	NUM
ajst-18313	100	3	]	]	X
ajst-18313	100	4	tong	tong	PROPN
ajst-18313	100	5	ling	ling	PROPN
ajst-18313	100	6	,	,	PUNCT
ajst-18313	100	7	huang	huang	PROPN
ajst-18313	100	8	guohui	guohui	PROPN
ajst-18313	100	9	,	,	PUNCT
ajst-18313	100	10	chen	chen	PROPN
ajst-18313	100	11	shanshuang	shanshuang	PROPN
ajst-18313	100	12	.	.	PUNCT
ajst-18313	100	13	anti	anti	ADJ
ajst-18313	100	14	-	-	ADJ
ajst-18313	100	15	gfp	gfp	ADJ
ajst-18313	100	16	nanoantibodies	nanoantibodie	NOUN
ajst-18313	100	17	for	for	ADP
ajst-18313	100	18	affinity	affinity	NOUN
ajst-18313	100	19	ligand	ligand	NOUN
ajst-18313	100	20	purification	purification	NOUN
ajst-18313	100	21	of	of	ADP
ajst-18313	100	22	gap	gap	NOUN
ajst-18313	100	23	junction	junction	NOUN
ajst-18313	100	24	protein	protein	NOUN
ajst-18313	100	25	26	26	NUM
ajst-18313	100	26	.	.	PUNCT
ajst-18313	101	1	biotechnology	biotechnology	NOUN
ajst-18313	101	2	,	,	PUNCT
ajst-18313	101	3	vol	vol	NOUN
ajst-18313	101	4	.	.	PROPN
ajst-18313	102	1	33	33	NUM
ajst-18313	102	2	(	(	PUNCT
ajst-18313	102	3	2022	2022	NUM
ajst-18313	102	4	)	)	PUNCT
ajst-18313	102	5	no.3	no.3	PROPN
ajst-18313	102	6	,	,	PUNCT
ajst-18313	102	7	p.281	p.281	NOUN
ajst-18313	102	8	-	-	SYM
ajst-18313	102	9	286	286	NUM
ajst-18313	102	10	.	.	PUNCT
ajst-18313	103	1	[	[	X
ajst-18313	103	2	3	3	X
ajst-18313	103	3	]	]	X
ajst-18313	103	4	yan	yan	PROPN
ajst-18313	103	5	wenlu	wenlu	PROPN
ajst-18313	103	6	,	,	PUNCT
ajst-18313	103	7	lang	lang	PROPN
ajst-18313	103	8	tianqun	tianqun	PROPN
ajst-18313	103	9	,	,	PUNCT
ajst-18313	103	10	yin	yin	PROPN
ajst-18313	103	11	qi	qi	PROPN
ajst-18313	103	12	,	,	PUNCT
ajst-18313	103	13	et	et	PROPN
ajst-18313	103	14	al	al	PROPN
ajst-18313	103	15	.	.	PROPN
ajst-18313	103	16	progress	progress	NOUN
ajst-18313	103	17	in	in	ADP
ajst-18313	103	18	improving	improve	VERB
ajst-18313	103	19	tumor	tumor	NOUN
ajst-18313	103	20	immunotherapy	immunotherapy	NOUN
ajst-18313	103	21	by	by	ADP
ajst-18313	103	22	actively	actively	ADV
ajst-18313	103	23	targeting	target	VERB
ajst-18313	103	24	nanodrug	nanodrug	NOUN
ajst-18313	103	25	delivery	delivery	NOUN
ajst-18313	103	26	systems	system	NOUN
ajst-18313	103	27	.	.	PUNCT
ajst-18313	104	1	acta	acta	PROPN
ajst-18313	104	2	pharmacologica	pharmacologica	PROPN
ajst-18313	104	3	sinica	sinica	PROPN
ajst-18313	104	4	,	,	PUNCT
ajst-18313	104	5	vol	vol	NOUN
ajst-18313	104	6	.	.	PROPN
ajst-18313	104	7	57	57	NUM
ajst-18313	104	8	(	(	PUNCT
ajst-18313	104	9	2022	2022	NUM
ajst-18313	104	10	)	)	PUNCT
ajst-18313	104	11	no.1	no.1	NOUN
ajst-18313	104	12	,	,	PUNCT
ajst-18313	104	13	p.208	p.208	NOUN
ajst-18313	104	14	-	-	SYM
ajst-18313	104	15	214	214	NUM
ajst-18313	104	16	.	.	PUNCT
ajst-18313	105	1	[	[	X
ajst-18313	105	2	4	4	X
ajst-18313	105	3	]	]	X
ajst-18313	105	4	wang	wang	PROPN
ajst-18313	105	5	yuxuan	yuxuan	PROPN
ajst-18313	105	6	,	,	PUNCT
ajst-18313	105	7	liu	liu	PROPN
ajst-18313	105	8	lin	lin	PROPN
ajst-18313	105	9	,	,	PUNCT
ajst-18313	105	10	liu	liu	PROPN
ajst-18313	105	11	mingfei	mingfei	PROPN
ajst-18313	105	12	,	,	PUNCT
ajst-18313	105	13	et	et	PROPN
ajst-18313	105	14	al	al	PROPN
ajst-18313	105	15	.	.	PUNCT
ajst-18313	105	16	preparation	preparation	NOUN
ajst-18313	105	17	of	of	ADP
ajst-18313	105	18	gdf15	gdf15	ADJ
ajst-18313	105	19	fusion	fusion	NOUN
ajst-18313	105	20	protein	protein	NOUN
ajst-18313	105	21	and	and	CCONJ
ajst-18313	105	22	its	its	PRON
ajst-18313	105	23	application	application	NOUN
ajst-18313	105	24	in	in	ADP
ajst-18313	105	25	non	non	ADJ
ajst-18313	105	26	-	-	ADJ
ajst-18313	105	27	alcoholic	alcoholic	ADJ
ajst-18313	105	28	steatohepatitis	steatohepatitis	NOUN
ajst-18313	105	29	.	.	PUNCT
ajst-18313	106	1	chinese	chinese	ADJ
ajst-18313	106	2	journal	journal	PROPN
ajst-18313	106	3	of	of	ADP
ajst-18313	106	4	hospital	hospital	NOUN
ajst-18313	106	5	pharmacy	pharmacy	NOUN
ajst-18313	106	6	,	,	PUNCT
ajst-18313	106	7	vol	vol	NOUN
ajst-18313	106	8	.	.	PROPN
ajst-18313	106	9	43	43	NUM
ajst-18313	106	10	(	(	PUNCT
ajst-18313	106	11	2023	2023	NUM
ajst-18313	106	12	)	)	PUNCT
ajst-18313	106	13	no.3	no.3	PROPN
ajst-18313	106	14	,	,	PUNCT
ajst-18313	106	15	p.2659	p.2659	X
ajst-18313	106	16	-	-	X
ajst-18313	106	17	2665	2665	NUM
ajst-18313	106	18	.	.	PUNCT
ajst-18313	107	1	[	[	X
ajst-18313	107	2	5	5	NUM
ajst-18313	107	3	]	]	X
ajst-18313	107	4	guo	guo	PROPN
ajst-18313	107	5	shujing	shujing	PROPN
ajst-18313	107	6	,	,	PUNCT
ajst-18313	107	7	wang	wang	PROPN
ajst-18313	107	8	xuede	xuede	PROPN
ajst-18313	107	9	,	,	PUNCT
ajst-18313	107	10	hu	hu	PROPN
ajst-18313	107	11	yuyuan	yuyuan	PROPN
ajst-18313	107	12	,	,	PUNCT
ajst-18313	107	13	et	et	PROPN
ajst-18313	107	14	al	al	PROPN
ajst-18313	107	15	.	.	PROPN
ajst-18313	107	16	advances	advance	NOUN
ajst-18313	107	17	in	in	ADP
ajst-18313	107	18	lipid	lipid	NOUN
ajst-18313	107	19	based	base	VERB
ajst-18313	107	20	nanoparticles	nanoparticle	NOUN
ajst-18313	107	21	and	and	CCONJ
ajst-18313	107	22	their	their	PRON
ajst-18313	107	23	use	use	NOUN
ajst-18313	107	24	as	as	ADP
ajst-18313	107	25	delivery	delivery	NOUN
ajst-18313	107	26	carriers	carrier	NOUN
ajst-18313	107	27	for	for	ADP
ajst-18313	107	28	phytosterols	phytosterol	NOUN
ajst-18313	107	29	.	.	PUNCT
ajst-18313	108	1	journal	journal	PROPN
ajst-18313	108	2	of	of	ADP
ajst-18313	108	3	henan	henan	PROPN
ajst-18313	108	4	university	university	PROPN
ajst-18313	108	5	of	of	ADP
ajst-18313	108	6	technology	technology	PROPN
ajst-18313	108	7	natural	natural	ADJ
ajst-18313	108	8	science	science	NOUN
ajst-18313	108	9	edition	edition	NOUN
ajst-18313	108	10	,	,	PUNCT
ajst-18313	108	11	vol	vol	NOUN
ajst-18313	108	12	.	.	PROPN
ajst-18313	108	13	44	44	NUM
ajst-18313	108	14	(	(	PUNCT
ajst-18313	108	15	2021	2021	NUM
ajst-18313	108	16	)	)	PUNCT
ajst-18313	108	17	no.6	no.6	PROPN
ajst-18313	108	18	,	,	PUNCT
ajst-18313	108	19	p.123	p.123	NOUN
ajst-18313	108	20	-	-	SYM
ajst-18313	108	21	129	129	NUM
ajst-18313	108	22	.	.	PUNCT
ajst-18313	109	1	[	[	X
ajst-18313	109	2	6	6	NUM
ajst-18313	109	3	]	]	X
ajst-18313	109	4	ren	ren	PROPN
ajst-18313	109	5	junwen	junwen	NOUN
ajst-18313	109	6	,	,	PUNCT
ajst-18313	109	7	jiang	jiang	PROPN
ajst-18313	109	8	guoqing	guoqing	PROPN
ajst-18313	109	9	,	,	PUNCT
ajst-18313	109	10	chen	chen	PROPN
ajst-18313	109	11	zhijie	zhijie	PROPN
ajst-18313	109	12	,	,	PUNCT
ajst-18313	109	13	et	et	PROPN
ajst-18313	109	14	al	al	PROPN
ajst-18313	109	15	.	.	PROPN
ajst-18313	109	16	surface	surface	NOUN
ajst-18313	109	17	structure	structure	NOUN
ajst-18313	109	18	design	design	NOUN
ajst-18313	109	19	of	of	ADP
ajst-18313	109	20	boron	boron	NOUN
ajst-18313	109	21	nitride	nitride	NOUN
ajst-18313	109	22	nanotubes	nanotube	NOUN
ajst-18313	109	23	and	and	CCONJ
ajst-18313	109	24	its	its	PRON
ajst-18313	109	25	mechanism	mechanism	NOUN
ajst-18313	109	26	of	of	ADP
ajst-18313	109	27	regulating	regulate	VERB
ajst-18313	109	28	the	the	DET
ajst-18313	109	29	properties	property	NOUN
ajst-18313	109	30	of	of	ADP
ajst-18313	109	31	epoxy	epoxy	NOUN
ajst-18313	109	32	composite	composite	ADJ
ajst-18313	109	33	dielectric	dielectric	NOUN
ajst-18313	109	34	.	.	PUNCT
ajst-18313	110	1	acta	acta	PROPN
ajst-18313	110	2	physica	physica	PROPN
ajst-18313	110	3	sinica	sinica	PROPN
ajst-18313	110	4	,	,	PUNCT
ajst-18313	110	5	vol	vol	NOUN
ajst-18313	110	6	.	.	PUNCT
ajst-18313	111	1	73	73	NUM
ajst-18313	111	2	(	(	PUNCT
ajst-18313	111	3	2022	2022	NUM
ajst-18313	111	4	)	)	PUNCT
ajst-18313	111	5	no.2	no.2	PROPN
ajst-18313	111	6	,	,	PUNCT
ajst-18313	111	7	p.02	p.02	NOUN
ajst-18313	111	8	-	-	PUNCT
ajst-18313	111	9	08	08	NUM
ajst-18313	111	10	.	.	PUNCT
ajst-18313	112	1	[	[	X
ajst-18313	112	2	7	7	X
ajst-18313	112	3	]	]	X
ajst-18313	112	4	lv	lv	PROPN
ajst-18313	112	5	jingwen	jingwen	PROPN
ajst-18313	112	6	.	.	PUNCT
ajst-18313	113	1	reliability	reliability	NOUN
ajst-18313	113	2	assignment	assignment	NOUN
ajst-18313	113	3	based	base	VERB
ajst-18313	113	4	on	on	ADP
ajst-18313	113	5	pythagorean	pythagorean	PROPN
ajst-18313	113	6	hesitancy	hesitancy	NOUN
ajst-18313	113	7	fuzzy	fuzzy	ADJ
ajst-18313	113	8	.	.	PUNCT
ajst-18313	114	1	operations	operation	NOUN
ajst-18313	114	2	research	research	NOUN
ajst-18313	114	3	and	and	CCONJ
ajst-18313	114	4	fuzzy	fuzzy	ADJ
ajst-18313	114	5	science	science	NOUN
ajst-18313	114	6	,	,	PUNCT
ajst-18313	114	7	vol	vol	NOUN
ajst-18313	114	8	.	.	PROPN
ajst-18313	114	9	13	13	NUM
ajst-18313	114	10	(	(	PUNCT
ajst-18313	114	11	2022	2022	NUM
ajst-18313	114	12	)	)	PUNCT
ajst-18313	114	13	no.6	no.6	PROPN
ajst-18313	114	14	,	,	PUNCT
ajst-18313	114	15	p.106	p.106	NOUN
ajst-18313	114	16	-	-	PUNCT
ajst-18313	114	17	114	114	NUM
ajst-18313	114	18	.	.	PUNCT
ajst-18313	115	1	[	[	X
ajst-18313	115	2	8	8	NUM
ajst-18313	115	3	]	]	X
ajst-18313	115	4	tang	tang	PROPN
ajst-18313	115	5	chunxia	chunxia	PROPN
ajst-18313	115	6	,	,	PUNCT
ajst-18313	115	7	li	li	PROPN
ajst-18313	115	8	meng	meng	PROPN
ajst-18313	115	9	,	,	PUNCT
ajst-18313	115	10	wang	wang	PROPN
ajst-18313	115	11	yuxi	yuxi	PROPN
ajst-18313	115	12	,	,	PUNCT
ajst-18313	115	13	etal	etal	NOUN
ajst-18313	115	14	.	.	PUNCT
ajst-18313	116	1	progress	progress	NOUN
ajst-18313	116	2	in	in	ADP
ajst-18313	116	3	structural	structural	ADJ
ajst-18313	116	4	design	design	NOUN
ajst-18313	116	5	of	of	ADP
ajst-18313	116	6	functionalized	functionalized	ADJ
ajst-18313	116	7	cellulose	cellulose	NOUN
ajst-18313	116	8	nanomaterials	nanomaterial	NOUN
ajst-18313	116	9	for	for	ADP
ajst-18313	116	10	cr(ⅵ	cr(ⅵ	NOUN
ajst-18313	116	11	)	)	PUNCT
ajst-18313	116	12	removal	removal	NOUN
ajst-18313	116	13	.	.	PUNCT
ajst-18313	117	1	advances	advance	NOUN
ajst-18313	117	2	in	in	ADP
ajst-18313	117	3	chemical	chemical	ADJ
ajst-18313	117	4	engineering	engineering	NOUN
ajst-18313	117	5	,	,	PUNCT
ajst-18313	117	6	vol	vol	NOUN
ajst-18313	117	7	.	.	PROPN
ajst-18313	118	1	42	42	NUM
ajst-18313	118	2	(	(	PUNCT
ajst-18313	118	3	2022	2022	NUM
ajst-18313	118	4	)	)	PUNCT
ajst-18313	118	5	no.2	no.2	PROPN
ajst-18313	118	6	,	,	PUNCT
ajst-18313	118	7	p.585	p.585	NOUN
ajst-18313	118	8	-	-	SYM
ajst-18313	118	9	594	594	NUM
ajst-18313	118	10	.	.	PUNCT
ajst-18313	119	1	[	[	X
ajst-18313	119	2	9	9	NUM
ajst-18313	119	3	]	]	X
ajst-18313	119	4	liu	liu	PROPN
ajst-18313	119	5	yong	yong	PROPN
ajst-18313	119	6	,	,	PUNCT
ajst-18313	119	7	xu	xu	PROPN
ajst-18313	119	8	zhewei	zhewei	PROPN
ajst-18313	119	9	,	,	PUNCT
ajst-18313	119	10	wang	wang	PROPN
ajst-18313	119	11	mingwei	mingwei	PROPN
ajst-18313	119	12	,	,	PUNCT
ajst-18313	119	13	et	et	PROPN
ajst-18313	119	14	al	al	PROPN
ajst-18313	119	15	.	.	PROPN
ajst-18313	119	16	design	design	NOUN
ajst-18313	119	17	and	and	CCONJ
ajst-18313	119	18	properties	property	NOUN
ajst-18313	119	19	of	of	ADP
ajst-18313	119	20	porous	porous	ADJ
ajst-18313	119	21	platinum	platinum	NOUN
ajst-18313	119	22	-	-	PUNCT
ajst-18313	119	23	based	base	VERB
ajst-18313	119	24	alloy	alloy	NOUN
ajst-18313	119	25	nanoelectrocatalytic	nanoelectrocatalytic	ADJ
ajst-18313	119	26	materials	material	NOUN
ajst-18313	119	27	.	.	PUNCT
ajst-18313	120	1	science	science	NOUN
ajst-18313	120	2	and	and	CCONJ
ajst-18313	120	3	technology	technology	NOUN
ajst-18313	120	4	achievements	achievement	NOUN
ajst-18313	120	5	in	in	ADP
ajst-18313	120	6	china	china	PROPN
ajst-18313	120	7	,	,	PUNCT
ajst-18313	120	8	vol	vol	NOUN
ajst-18313	120	9	.	.	PROPN
ajst-18313	120	10	24	24	NUM
ajst-18313	120	11	(	(	PUNCT
ajst-18313	120	12	2023	2023	NUM
ajst-18313	120	13	)	)	PUNCT
ajst-18313	120	14	no.6	no.6	PROPN
ajst-18313	120	15	,	,	PUNCT
ajst-18313	120	16	p.4	p.4	NOUN
ajst-18313	120	17	-	-	PUNCT
ajst-18313	120	18	8	8	NUM
ajst-18313	120	19	.	.	PUNCT
ajst-18313	121	1	[	[	X
ajst-18313	121	2	10	10	NUM
ajst-18313	121	3	]	]	X
ajst-18313	121	4	kuang	kuang	PROPN
ajst-18313	121	5	h	h	PROPN
ajst-18313	121	6	y	y	PROPN
ajst-18313	121	7	,	,	PUNCT
ajst-18313	121	8	chen	chen	PROPN
ajst-18313	121	9	c.	c.	PROPN
ajst-18313	121	10	research	research	PROPN
ajst-18313	121	11	progress	progress	NOUN
ajst-18313	121	12	in	in	ADP
ajst-18313	121	13	the	the	DET
ajst-18313	121	14	design	design	NOUN
ajst-18313	121	15	,	,	PUNCT
ajst-18313	121	16	synthesis	synthesis	NOUN
ajst-18313	121	17	and	and	CCONJ
ajst-18313	121	18	electrocatalytic	electrocatalytic	ADJ
ajst-18313	121	19	performance	performance	NOUN
ajst-18313	121	20	of	of	ADP
ajst-18313	121	21	precious	precious	ADJ
ajst-18313	121	22	metal	metal	NOUN
ajst-18313	121	23	nanoframes	nanoframe	NOUN
ajst-18313	121	24	.	.	PUNCT
ajst-18313	122	1	journal	journal	NOUN
ajst-18313	122	2	of	of	ADP
ajst-18313	122	3	chemistry	chemistry	NOUN
ajst-18313	122	4	of	of	ADP
ajst-18313	122	5	chinese	chinese	ADJ
ajst-18313	122	6	universities	university	NOUN
ajst-18313	122	7	,	,	PUNCT
ajst-18313	122	8	vol	vol	NOUN
ajst-18313	122	9	.	.	PROPN
ajst-18313	122	10	23	23	NUM
ajst-18313	122	11	,	,	PUNCT
ajst-18313	122	12	44	44	NUM
ajst-18313	122	13	(	(	PUNCT
ajst-18313	122	14	2022	2022	NUM
ajst-18313	122	15	)	)	PUNCT
ajst-18313	122	16	no.1	no.1	NOUN
ajst-18313	122	17	,	,	PUNCT
ajst-18313	122	18	p.202	p.202	NOUN
ajst-18313	122	19	-	-	PUNCT
ajst-18313	122	20	209	209	NUM
ajst-18313	122	21	.	.	PUNCT
ajst-18313	123	1	[	[	X
ajst-18313	123	2	11	11	NUM
ajst-18313	123	3	]	]	X
ajst-18313	123	4	yang	yang	PROPN
ajst-18313	123	5	qhua	qhua	PROPN
ajst-18313	123	6	,	,	PUNCT
ajst-18313	123	7	liu	liu	PROPN
ajst-18313	123	8	yuheng	yuheng	PROPN
ajst-18313	123	9	,	,	PUNCT
ajst-18313	123	10	zhang	zhang	PROPN
ajst-18313	123	11	dandan	dandan	PROPN
ajst-18313	123	12	,	,	PUNCT
ajst-18313	123	13	etal	etal	NOUN
ajst-18313	123	14	.	.	PUNCT
ajst-18313	124	1	study	study	NOUN
ajst-18313	124	2	on	on	ADP
ajst-18313	124	3	respiratory	respiratory	ADJ
ajst-18313	124	4	mucosal	mucosal	NOUN
ajst-18313	124	5	mrna	mrna	PROPN
ajst-18313	124	6	vaccine	vaccine	NOUN
ajst-18313	124	7	based	base	VERB
ajst-18313	124	8	on	on	ADP
ajst-18313	124	9	polypeptidespoloxamide	polypeptidespoloxamide	NOUN
ajst-18313	124	10	nanoparticle	nanoparticle	NOUN
ajst-18313	124	11	carrier	carrier	NOUN
ajst-18313	124	12	.	.	PUNCT
ajst-18313	125	1	journal	journal	PROPN
ajst-18313	125	2	of	of	ADP
ajst-18313	125	3	army	army	PROPN
ajst-18313	125	4	medical	medical	PROPN
ajst-18313	125	5	university	university	PROPN
ajst-18313	125	6	,	,	PUNCT
ajst-18313	125	7	vol	vol	NOUN
ajst-18313	125	8	.	.	PROPN
ajst-18313	125	9	45	45	NUM
ajst-18313	125	10	(	(	PUNCT
ajst-18313	125	11	2023	2023	NUM
ajst-18313	125	12	)	)	PUNCT
ajst-18313	125	13	no.3	no.3	NOUN
ajst-18313	125	14	,	,	PUNCT
ajst-18313	125	15	p.1377	p.1377	NOUN
ajst-18313	125	16	-	-	PUNCT
ajst-18313	125	17	1387	1387	NUM
ajst-18313	125	18	.	.	PUNCT
ajst-18313	126	1	[	[	X
ajst-18313	126	2	12	12	NUM
ajst-18313	126	3	]	]	X
ajst-18313	126	4	bao	bao	PROPN
ajst-18313	126	5	wen	wen	PROPN
ajst-18313	126	6	,	,	PUNCT
ajst-18313	126	7	liu	liu	PROPN
ajst-18313	126	8	ran	run	VERB
ajst-18313	126	9	,	,	PUNCT
ajst-18313	126	10	wang	wang	PROPN
ajst-18313	126	11	fei	fei	PROPN
ajst-18313	126	12	,	,	PUNCT
ajst-18313	126	13	et	et	PROPN
ajst-18313	126	14	al	al	PROPN
ajst-18313	126	15	.	.	PROPN
ajst-18313	127	1	basic	basic	ADJ
ajst-18313	127	2	study	study	NOUN
ajst-18313	127	3	of	of	ADP
ajst-18313	127	4	transferritin	transferritin	NOUN
ajst-18313	127	5	receptor	receptor	NOUN
ajst-18313	127	6	monoclonal	monoclonal	NOUN
ajst-18313	127	7	antibody	antibody	NOUN
ajst-18313	127	8	nanoparticle	nanoparticle	NOUN
ajst-18313	127	9	drug	drug	NOUN
ajst-18313	127	10	delivery	delivery	NOUN
ajst-18313	127	11	system	system	NOUN
ajst-18313	127	12	in	in	ADP
ajst-18313	127	13	the	the	DET
ajst-18313	127	14	treatment	treatment	NOUN
ajst-18313	127	15	of	of	ADP
ajst-18313	127	16	leukemia	leukemia	NOUN
ajst-18313	127	17	.	.	PUNCT
ajst-18313	128	1	chinese	chinese	ADJ
ajst-18313	128	2	journal	journal	PROPN
ajst-18313	128	3	of	of	ADP
ajst-18313	128	4	experimental	experimental	ADJ
ajst-18313	128	5	hematology	hematology	NOUN
ajst-18313	128	6	,	,	PUNCT
ajst-18313	128	7	vol.31	vol.31	NOUN
ajst-18313	128	8	(	(	PUNCT
ajst-18313	128	9	2022	2022	NUM
ajst-18313	128	10	)	)	PUNCT
ajst-18313	128	11	no.4):939	no.4):939	X
ajst-18313	128	12	-	-	SYM
ajst-18313	128	13	944	944	NUM
ajst-18313	128	14	.	.	PUNCT
ajst-18313	129	1	[	[	X
ajst-18313	129	2	13	13	NUM
ajst-18313	129	3	]	]	SYM
ajst-18313	129	4	hu	hu	PROPN
ajst-18313	129	5	xiangyun	xiangyun	PROPN
ajst-18313	129	6	,	,	PUNCT
ajst-18313	129	7	cao	cao	PROPN
ajst-18313	129	8	yan	yan	PROPN
ajst-18313	129	9	-	-	PROPN
ajst-18313	129	10	hong	hong	PROPN
ajst-18313	129	11	,	,	PUNCT
ajst-18313	129	12	lv	lv	PROPN
ajst-18313	129	13	lingyan	lingyan	PROPN
ajst-18313	129	14	,	,	PUNCT
ajst-18313	129	15	et	et	PROPN
ajst-18313	129	16	al	al	PROPN
ajst-18313	129	17	.	.	PROPN
ajst-18313	129	18	nanoantibody	nanoantibody	PROPN
ajst-18313	129	19	and	and	CCONJ
ajst-18313	129	20	its	its	PRON
ajst-18313	129	21	research	research	NOUN
ajst-18313	129	22	status	status	NOUN
ajst-18313	129	23	in	in	ADP
ajst-18313	129	24	veterinary	veterinary	ADJ
ajst-18313	129	25	field	field	NOUN
ajst-18313	129	26	.	.	PUNCT
ajst-18313	130	1	journal	journal	NOUN
ajst-18313	130	2	of	of	ADP
ajst-18313	130	3	animal	animal	NOUN
ajst-18313	130	4	science	science	NOUN
ajst-18313	130	5	and	and	CCONJ
ajst-18313	130	6	veterinary	veterinary	ADJ
ajst-18313	130	7	medicine	medicine	NOUN
ajst-18313	130	8	,	,	PUNCT
ajst-18313	130	9	vol.54	vol.54	PROPN
ajst-18313	130	10	(	(	PUNCT
ajst-18313	130	11	2022	2022	NUM
ajst-18313	130	12	)	)	PUNCT
ajst-18313	130	13	no.8):3164	no.8):3164	NOUN
ajst-18313	130	14	-	-	SYM
ajst-18313	130	15	3172	3172	NUM
ajst-18313	130	16	.	.	PUNCT
ajst-18313	131	1	[	[	X
ajst-18313	131	2	14	14	NUM
ajst-18313	131	3	]	]	X
ajst-18313	131	4	wu	wu	PROPN
ajst-18313	131	5	yue	yue	PROPN
ajst-18313	131	6	,	,	PUNCT
ajst-18313	131	7	sun	sun	NOUN
ajst-18313	131	8	baihe	baihe	NOUN
ajst-18313	131	9	,	,	PUNCT
ajst-18313	131	10	zhao	zhao	PROPN
ajst-18313	131	11	rui	rui	PROPN
ajst-18313	131	12	,	,	PUNCT
ajst-18313	131	13	et	et	PROPN
ajst-18313	131	14	al	al	PROPN
ajst-18313	131	15	.	.	PUNCT
ajst-18313	131	16	research	research	NOUN
ajst-18313	131	17	progress	progress	NOUN
ajst-18313	131	18	of	of	ADP
ajst-18313	131	19	therapeutic	therapeutic	ADJ
ajst-18313	131	20	nanoantibodies	nanoantibodie	NOUN
ajst-18313	131	21	in	in	ADP
ajst-18313	131	22	different	different	ADJ
ajst-18313	131	23	drug	drug	NOUN
ajst-18313	131	24	delivery	delivery	NOUN
ajst-18313	131	25	routes	route	NOUN
ajst-18313	131	26	.	.	PUNCT
ajst-18313	132	1	chinese	chinese	ADJ
ajst-18313	132	2	journal	journal	PROPN
ajst-18313	132	3	of	of	ADP
ajst-18313	132	4	bioengineering	bioengineering	NOUN
ajst-18313	132	5	,	,	PUNCT
ajst-18313	132	6	vol.43	vol.43	NOUN
ajst-18313	132	7	(	(	PUNCT
ajst-18313	132	8	2023	2023	NUM
ajst-18313	132	9	)	)	PUNCT
ajst-18313	132	10	no.1):120126	no.1):120126	PROPN
ajst-18313	132	11	.	.	PUNCT