id	sid	tid	token	lemma	pos
ajst-20185	1	1	academic	academic	ADJ
ajst-20185	1	2	journal	journal	NOUN
ajst-20185	1	3	of	of	ADP
ajst-20185	1	4	science	science	NOUN
ajst-20185	1	5	and	and	CCONJ
ajst-20185	1	6	technology	technology	NOUN
ajst-20185	1	7	issn	issn	NOUN
ajst-20185	1	8	:	:	PUNCT
ajst-20185	1	9	2771	2771	NUM
ajst-20185	1	10	-	-	SYM
ajst-20185	1	11	3032	3032	NUM
ajst-20185	1	12	|	|	NOUN
ajst-20185	1	13	vol	vol	NOUN
ajst-20185	1	14	.	.	PROPN
ajst-20185	2	1	10	10	NUM
ajst-20185	2	2	,	,	PUNCT
ajst-20185	2	3	no	no	INTJ
ajst-20185	2	4	.	.	NOUN
ajst-20185	2	5	2	2	NUM
ajst-20185	2	6	,	,	PUNCT
ajst-20185	2	7	2024	2024	NUM
ajst-20185	2	8	55	55	NUM
ajst-20185	2	9	the	the	DET
ajst-20185	2	10	evolutionary	evolutionary	ADJ
ajst-20185	2	11	process	process	NOUN
ajst-20185	2	12	of	of	ADP
ajst-20185	2	13	acid	acid	ADJ
ajst-20185	2	14	adaptation	adaptation	NOUN
ajst-20185	2	15	and	and	CCONJ
ajst-20185	2	16	deep	deep	ADJ
ajst-20185	2	17	transcriptional	transcriptional	ADJ
ajst-20185	2	18	analysis	analysis	NOUN
ajst-20185	2	19	in	in	ADP
ajst-20185	2	20	bacillus	bacillus	NOUN
ajst-20185	2	21	subtilis	subtili	NOUN
ajst-20185	2	22	168	168	NUM
ajst-20185	2	23	zhongjie	zhongjie	PROPN
ajst-20185	2	24	yan	yan	PROPN
ajst-20185	2	25	,	,	PUNCT
ajst-20185	2	26	junming	junme	VERB
ajst-20185	2	27	wang	wang	PROPN
ajst-20185	3	1	*	*	PROPN
ajst-20185	3	2	,	,	PUNCT
ajst-20185	4	1	xinli	xinli	PROPN
ajst-20185	4	2	liu	liu	PROPN
ajst-20185	4	3	*	*	PROPN
ajst-20185	4	4	,	,	PUNCT
ajst-20185	4	5	chi	chi	PROPN
ajst-20185	4	6	zhang	zhang	PROPN
ajst-20185	4	7	,	,	PUNCT
ajst-20185	4	8	xiufang	xiufang	PROPN
ajst-20185	4	9	li	li	PROPN
ajst-20185	4	10	faculty	faculty	PROPN
ajst-20185	4	11	of	of	ADP
ajst-20185	4	12	bioengineering	bioengineering	NOUN
ajst-20185	4	13	,	,	PUNCT
ajst-20185	4	14	qilu	qilu	NOUN
ajst-20185	4	15	university	university	PROPN
ajst-20185	4	16	of	of	ADP
ajst-20185	4	17	technology	technology	NOUN
ajst-20185	4	18	(	(	PUNCT
ajst-20185	4	19	shandong	shandong	PROPN
ajst-20185	4	20	academy	academy	PROPN
ajst-20185	4	21	of	of	ADP
ajst-20185	4	22	sciences	sciences	PROPN
ajst-20185	4	23	)	)	PUNCT
ajst-20185	4	24	,	,	PUNCT
ajst-20185	4	25	jinan	jinan	PROPN
ajst-20185	4	26	250353	250353	NUM
ajst-20185	4	27	,	,	PUNCT
ajst-20185	4	28	china	china	PROPN
ajst-20185	4	29	*	*	PUNCT
ajst-20185	4	30	corresponding	correspond	VERB
ajst-20185	4	31	author	author	NOUN
ajst-20185	4	32	abstract	abstract	NOUN
ajst-20185	4	33	:	:	PUNCT
ajst-20185	4	34	this	this	DET
ajst-20185	4	35	study	study	NOUN
ajst-20185	4	36	is	be	AUX
ajst-20185	4	37	focused	focus	VERB
ajst-20185	4	38	on	on	ADP
ajst-20185	4	39	investigating	investigate	VERB
ajst-20185	4	40	the	the	DET
ajst-20185	4	41	variations	variation	NOUN
ajst-20185	4	42	in	in	ADP
ajst-20185	4	43	gene	gene	NOUN
ajst-20185	4	44	expression	expression	NOUN
ajst-20185	4	45	of	of	ADP
ajst-20185	4	46	bacillus	bacillus	NOUN
ajst-20185	4	47	subtilis	subtili	NOUN
ajst-20185	4	48	168	168	NUM
ajst-20185	4	49	following	follow	VERB
ajst-20185	4	50	acid	acid	NOUN
ajst-20185	4	51	adaptation	adaptation	NOUN
ajst-20185	4	52	evolution	evolution	NOUN
ajst-20185	4	53	.	.	PUNCT
ajst-20185	5	1	through	through	ADP
ajst-20185	5	2	simulating	simulate	VERB
ajst-20185	5	3	prolonged	prolonged	ADJ
ajst-20185	5	4	cultivation	cultivation	NOUN
ajst-20185	5	5	in	in	ADP
ajst-20185	5	6	a	a	DET
ajst-20185	5	7	natural	natural	ADJ
ajst-20185	5	8	acidic	acidic	ADJ
ajst-20185	5	9	setting	setting	NOUN
ajst-20185	5	10	,	,	PUNCT
ajst-20185	5	11	we	we	PRON
ajst-20185	5	12	have	have	AUX
ajst-20185	5	13	observed	observe	VERB
ajst-20185	5	14	the	the	DET
ajst-20185	5	15	occurrence	occurrence	NOUN
ajst-20185	5	16	of	of	ADP
ajst-20185	5	17	adaptive	adaptive	ADJ
ajst-20185	5	18	evolution	evolution	NOUN
ajst-20185	5	19	within	within	ADP
ajst-20185	5	20	the	the	DET
ajst-20185	5	21	strain	strain	NOUN
ajst-20185	5	22	and	and	CCONJ
ajst-20185	5	23	conducted	conduct	VERB
ajst-20185	5	24	an	an	DET
ajst-20185	5	25	extensive	extensive	ADJ
ajst-20185	5	26	analysis	analysis	NOUN
ajst-20185	5	27	of	of	ADP
ajst-20185	5	28	gene	gene	NOUN
ajst-20185	5	29	expression	expression	NOUN
ajst-20185	5	30	in	in	ADP
ajst-20185	5	31	the	the	DET
ajst-20185	5	32	evolved	evolved	ADJ
ajst-20185	5	33	strain	strain	NOUN
ajst-20185	5	34	using	use	VERB
ajst-20185	5	35	highthroughput	highthroughput	VERB
ajst-20185	5	36	transcriptomics	transcriptomic	NOUN
ajst-20185	5	37	technology	technology	NOUN
ajst-20185	5	38	.	.	PUNCT
ajst-20185	6	1	the	the	DET
ajst-20185	6	2	findings	finding	NOUN
ajst-20185	6	3	from	from	ADP
ajst-20185	6	4	this	this	DET
ajst-20185	6	5	research	research	NOUN
ajst-20185	6	6	shed	shed	VERB
ajst-20185	6	7	light	light	NOUN
ajst-20185	6	8	on	on	ADP
ajst-20185	6	9	the	the	DET
ajst-20185	6	10	fundamental	fundamental	ADJ
ajst-20185	6	11	molecular	molecular	ADJ
ajst-20185	6	12	mechanisms	mechanism	NOUN
ajst-20185	6	13	employed	employ	VERB
ajst-20185	6	14	by	by	ADP
ajst-20185	6	15	bacillus	bacillus	NOUN
ajst-20185	6	16	subtilis	subtili	NOUN
ajst-20185	6	17	to	to	PART
ajst-20185	6	18	adapt	adapt	VERB
ajst-20185	6	19	to	to	ADP
ajst-20185	6	20	acidic	acidic	ADJ
ajst-20185	6	21	environments	environment	NOUN
ajst-20185	6	22	,	,	PUNCT
ajst-20185	6	23	thereby	thereby	ADV
ajst-20185	6	24	providing	provide	VERB
ajst-20185	6	25	crucial	crucial	ADJ
ajst-20185	6	26	scientific	scientific	ADJ
ajst-20185	6	27	evidence	evidence	NOUN
ajst-20185	6	28	for	for	ADP
ajst-20185	6	29	comprehending	comprehend	VERB
ajst-20185	6	30	its	its	PRON
ajst-20185	6	31	survival	survival	NOUN
ajst-20185	6	32	strategies	strategy	NOUN
ajst-20185	6	33	and	and	CCONJ
ajst-20185	6	34	potential	potential	ADJ
ajst-20185	6	35	applications	application	NOUN
ajst-20185	6	36	in	in	ADP
ajst-20185	6	37	acidic	acidic	ADJ
ajst-20185	6	38	settings	setting	NOUN
ajst-20185	6	39	.	.	PUNCT
ajst-20185	7	1	1	1	NUM
ajst-20185	7	2	.	.	SYM
ajst-20185	7	3	1	1	NUM
ajst-20185	7	4	introduction	introduction	NOUN
ajst-20185	7	5	bacillus	bacillus	NOUN
ajst-20185	7	6	subtilis	subtili	NOUN
ajst-20185	7	7	,	,	PUNCT
ajst-20185	7	8	a	a	DET
ajst-20185	7	9	gram	gram	NOUN
ajst-20185	7	10	-	-	PUNCT
ajst-20185	7	11	positive	positive	ADJ
ajst-20185	7	12	bacterium	bacterium	NOUN
ajst-20185	7	13	,	,	PUNCT
ajst-20185	7	14	is	be	AUX
ajst-20185	7	15	widely	widely	ADV
ajst-20185	7	16	distributed	distribute	VERB
ajst-20185	7	17	in	in	ADP
ajst-20185	7	18	soil	soil	NOUN
ajst-20185	7	19	,	,	PUNCT
ajst-20185	7	20	plant	plant	NOUN
ajst-20185	7	21	surfaces	surface	NOUN
ajst-20185	7	22	,	,	PUNCT
ajst-20185	7	23	and	and	CCONJ
ajst-20185	7	24	air	air	NOUN
ajst-20185	8	1	[	[	X
ajst-20185	8	2	1	1	NUM
ajst-20185	8	3	]	]	PUNCT
ajst-20185	8	4	.	.	PUNCT
ajst-20185	9	1	its	its	PRON
ajst-20185	9	2	exceptional	exceptional	ADJ
ajst-20185	9	3	adaptability	adaptability	NOUN
ajst-20185	9	4	and	and	CCONJ
ajst-20185	9	5	versatility	versatility	NOUN
ajst-20185	9	6	have	have	AUX
ajst-20185	9	7	led	lead	VERB
ajst-20185	9	8	to	to	ADP
ajst-20185	9	9	significant	significant	ADJ
ajst-20185	9	10	applications	application	NOUN
ajst-20185	9	11	across	across	ADP
ajst-20185	9	12	various	various	ADJ
ajst-20185	9	13	fields	field	NOUN
ajst-20185	9	14	.	.	PUNCT
ajst-20185	10	1	since	since	SCONJ
ajst-20185	10	2	its	its	PRON
ajst-20185	10	3	initial	initial	ADJ
ajst-20185	10	4	description	description	NOUN
ajst-20185	10	5	and	and	CCONJ
ajst-20185	10	6	classification	classification	NOUN
ajst-20185	10	7	in	in	ADP
ajst-20185	10	8	the	the	DET
ajst-20185	10	9	19th	19th	ADJ
ajst-20185	10	10	century	century	NOUN
ajst-20185	10	11	,	,	PUNCT
ajst-20185	10	12	it	it	PRON
ajst-20185	10	13	has	have	AUX
ajst-20185	10	14	been	be	AUX
ajst-20185	10	15	a	a	DET
ajst-20185	10	16	focal	focal	ADJ
ajst-20185	10	17	point	point	NOUN
ajst-20185	10	18	of	of	ADP
ajst-20185	10	19	microbiological	microbiological	ADJ
ajst-20185	10	20	research	research	NOUN
ajst-20185	10	21	[	[	X
ajst-20185	10	22	2	2	NUM
ajst-20185	10	23	]	]	PUNCT
ajst-20185	10	24	.	.	PUNCT
ajst-20185	11	1	from	from	ADP
ajst-20185	11	2	early	early	ADJ
ajst-20185	11	3	investigations	investigation	NOUN
ajst-20185	11	4	into	into	ADP
ajst-20185	11	5	biological	biological	ADJ
ajst-20185	11	6	characteristics	characteristic	NOUN
ajst-20185	11	7	to	to	ADP
ajst-20185	11	8	subsequent	subsequent	ADJ
ajst-20185	11	9	studies	study	NOUN
ajst-20185	11	10	on	on	ADP
ajst-20185	11	11	gene	gene	NOUN
ajst-20185	11	12	expression	expression	NOUN
ajst-20185	11	13	,	,	PUNCT
ajst-20185	11	14	regulation	regulation	NOUN
ajst-20185	11	15	,	,	PUNCT
ajst-20185	11	16	and	and	CCONJ
ajst-20185	11	17	genetic	genetic	ADJ
ajst-20185	11	18	mechanisms	mechanism	NOUN
ajst-20185	11	19	,	,	PUNCT
ajst-20185	11	20	bacillus	bacillus	NOUN
ajst-20185	11	21	subtilis	subtili	NOUN
ajst-20185	11	22	has	have	AUX
ajst-20185	11	23	consistently	consistently	ADV
ajst-20185	11	24	played	play	VERB
ajst-20185	11	25	a	a	DET
ajst-20185	11	26	pivotal	pivotal	ADJ
ajst-20185	11	27	role	role	NOUN
ajst-20185	11	28	[	[	X
ajst-20185	11	29	3	3	NUM
ajst-20185	11	30	]	]	PUNCT
ajst-20185	11	31	.	.	PUNCT
ajst-20185	12	1	notably	notably	ADV
ajst-20185	12	2	,	,	PUNCT
ajst-20185	12	3	the	the	DET
ajst-20185	12	4	completion	completion	NOUN
ajst-20185	12	5	of	of	ADP
ajst-20185	12	6	its	its	PRON
ajst-20185	12	7	genetic	genetic	ADJ
ajst-20185	12	8	map	map	NOUN
ajst-20185	12	9	in	in	ADP
ajst-20185	12	10	the	the	DET
ajst-20185	12	11	mid	mid	NOUN
ajst-20185	12	12	-	-	PUNCT
ajst-20185	12	13	to	to	ADP
ajst-20185	12	14	-	-	PUNCT
ajst-20185	12	15	late	late	ADJ
ajst-20185	12	16	20th	20th	ADJ
ajst-20185	12	17	century	century	NOUN
ajst-20185	12	18	further	far	ADV
ajst-20185	12	19	accelerated	accelerate	VERB
ajst-20185	12	20	subsequent	subsequent	ADJ
ajst-20185	12	21	advancements	advancement	NOUN
ajst-20185	12	22	in	in	ADP
ajst-20185	12	23	gene	gene	NOUN
ajst-20185	12	24	manipulation	manipulation	NOUN
ajst-20185	12	25	and	and	CCONJ
ajst-20185	12	26	functional	functional	ADJ
ajst-20185	12	27	studies	study	NOUN
ajst-20185	12	28	[	[	X
ajst-20185	12	29	4	4	NUM
ajst-20185	12	30	]	]	PUNCT
ajst-20185	12	31	.	.	PUNCT
ajst-20185	13	1	the	the	DET
ajst-20185	13	2	potential	potential	ADJ
ajst-20185	13	3	applications	application	NOUN
ajst-20185	13	4	of	of	ADP
ajst-20185	13	5	bacillus	bacillus	NOUN
ajst-20185	13	6	subtilis	subtili	NOUN
ajst-20185	13	7	in	in	ADP
ajst-20185	13	8	biotechnology	biotechnology	NOUN
ajst-20185	13	9	,	,	PUNCT
ajst-20185	13	10	agriculture	agriculture	NOUN
ajst-20185	13	11	,	,	PUNCT
ajst-20185	13	12	the	the	DET
ajst-20185	13	13	food	food	NOUN
ajst-20185	13	14	industry	industry	NOUN
ajst-20185	13	15	,	,	PUNCT
ajst-20185	13	16	and	and	CCONJ
ajst-20185	13	17	environmental	environmental	ADJ
ajst-20185	13	18	science	science	NOUN
ajst-20185	13	19	are	be	AUX
ajst-20185	13	20	continuously	continuously	ADV
ajst-20185	13	21	being	be	AUX
ajst-20185	13	22	revealed	reveal	VERB
ajst-20185	13	23	.	.	PUNCT
ajst-20185	14	1	with	with	ADP
ajst-20185	14	2	the	the	DET
ajst-20185	14	3	advent	advent	NOUN
ajst-20185	14	4	of	of	ADP
ajst-20185	14	5	systems	system	NOUN
ajst-20185	14	6	biology	biology	NOUN
ajst-20185	14	7	research	research	NOUN
ajst-20185	14	8	methodologies	methodology	NOUN
ajst-20185	14	9	,	,	PUNCT
ajst-20185	14	10	it	it	PRON
ajst-20185	14	11	has	have	AUX
ajst-20185	14	12	become	become	VERB
ajst-20185	14	13	an	an	DET
ajst-20185	14	14	essential	essential	ADJ
ajst-20185	14	15	tool	tool	NOUN
ajst-20185	14	16	for	for	ADP
ajst-20185	14	17	investigating	investigate	VERB
ajst-20185	14	18	intricate	intricate	ADJ
ajst-20185	14	19	biological	biological	ADJ
ajst-20185	14	20	systems	system	NOUN
ajst-20185	14	21	and	and	CCONJ
ajst-20185	14	22	metabolic	metabolic	NOUN
ajst-20185	14	23	networks	network	NOUN
ajst-20185	14	24	[	[	X
ajst-20185	14	25	5	5	NUM
ajst-20185	14	26	]	]	PUNCT
ajst-20185	14	27	.	.	PUNCT
ajst-20185	15	1	however	however	ADV
ajst-20185	15	2	,	,	PUNCT
ajst-20185	15	3	in	in	ADP
ajst-20185	15	4	practical	practical	ADJ
ajst-20185	15	5	applications	application	NOUN
ajst-20185	15	6	,	,	PUNCT
ajst-20185	15	7	particularly	particularly	ADV
ajst-20185	15	8	in	in	ADP
ajst-20185	15	9	specific	specific	ADJ
ajst-20185	15	10	industrial	industrial	ADJ
ajst-20185	15	11	processes	process	NOUN
ajst-20185	15	12	requiring	require	VERB
ajst-20185	15	13	acidic	acidic	ADJ
ajst-20185	15	14	fermentation	fermentation	NOUN
ajst-20185	15	15	conditions	condition	NOUN
ajst-20185	15	16	[	[	X
ajst-20185	15	17	6	6	NUM
ajst-20185	15	18	]	]	PUNCT
ajst-20185	15	19	,	,	PUNCT
ajst-20185	15	20	the	the	DET
ajst-20185	15	21	viability	viability	NOUN
ajst-20185	15	22	of	of	ADP
ajst-20185	15	23	bacillus	bacillus	NOUN
ajst-20185	15	24	subtilis	subtili	NOUN
ajst-20185	15	25	is	be	AUX
ajst-20185	15	26	often	often	ADV
ajst-20185	15	27	significantly	significantly	ADV
ajst-20185	15	28	compromised	compromise	VERB
ajst-20185	15	29	,	,	PUNCT
ajst-20185	15	30	thereby	thereby	ADV
ajst-20185	15	31	constraining	constrain	VERB
ajst-20185	15	32	production	production	NOUN
ajst-20185	15	33	efficiency	efficiency	NOUN
ajst-20185	15	34	.	.	PUNCT
ajst-20185	16	1	in	in	ADP
ajst-20185	16	2	order	order	NOUN
ajst-20185	16	3	to	to	PART
ajst-20185	16	4	tackle	tackle	VERB
ajst-20185	16	5	this	this	DET
ajst-20185	16	6	issue	issue	NOUN
ajst-20185	16	7	,	,	PUNCT
ajst-20185	16	8	we	we	PRON
ajst-20185	16	9	propose	propose	VERB
ajst-20185	16	10	a	a	DET
ajst-20185	16	11	solution	solution	NOUN
ajst-20185	16	12	rooted	root	VERB
ajst-20185	16	13	in	in	ADP
ajst-20185	16	14	adaptive	adaptive	ADJ
ajst-20185	16	15	evolution	evolution	NOUN
ajst-20185	16	16	[	[	X
ajst-20185	16	17	7	7	NUM
ajst-20185	16	18	]	]	PUNCT
ajst-20185	16	19	.	.	PUNCT
ajst-20185	17	1	adaptive	adaptive	ADJ
ajst-20185	17	2	evolution	evolution	NOUN
ajst-20185	17	3	refers	refer	VERB
ajst-20185	17	4	to	to	ADP
ajst-20185	17	5	the	the	DET
ajst-20185	17	6	process	process	NOUN
ajst-20185	17	7	by	by	ADP
ajst-20185	17	8	which	which	PRON
ajst-20185	17	9	organisms	organism	NOUN
ajst-20185	17	10	bolster	bolster	VERB
ajst-20185	17	11	their	their	PRON
ajst-20185	17	12	survival	survival	NOUN
ajst-20185	17	13	and	and	CCONJ
ajst-20185	17	14	reproductive	reproductive	ADJ
ajst-20185	17	15	capabilities	capability	NOUN
ajst-20185	17	16	through	through	ADP
ajst-20185	17	17	genetic	genetic	ADJ
ajst-20185	17	18	and	and	CCONJ
ajst-20185	17	19	physiological	physiological	ADJ
ajst-20185	17	20	changes	change	NOUN
ajst-20185	17	21	in	in	ADP
ajst-20185	17	22	response	response	NOUN
ajst-20185	17	23	to	to	ADP
ajst-20185	17	24	specific	specific	ADJ
ajst-20185	17	25	environmental	environmental	ADJ
ajst-20185	17	26	pressures	pressure	NOUN
ajst-20185	17	27	[	[	X
ajst-20185	17	28	8	8	NUM
ajst-20185	17	29	]	]	PUNCT
ajst-20185	17	30	.	.	PUNCT
ajst-20185	18	1	in	in	ADP
ajst-20185	18	2	an	an	DET
ajst-20185	18	3	acidic	acidic	ADJ
ajst-20185	18	4	environment	environment	NOUN
ajst-20185	18	5	,	,	PUNCT
ajst-20185	18	6	genetic	genetic	ADJ
ajst-20185	18	7	variations	variation	NOUN
ajst-20185	18	8	that	that	PRON
ajst-20185	18	9	promote	promote	VERB
ajst-20185	18	10	adaptation	adaptation	NOUN
ajst-20185	18	11	to	to	ADP
ajst-20185	18	12	low	low	ADJ
ajst-20185	18	13	ph	ph	NOUN
ajst-20185	18	14	conditions	condition	NOUN
ajst-20185	18	15	are	be	AUX
ajst-20185	18	16	favored	favor	VERB
ajst-20185	18	17	by	by	ADP
ajst-20185	18	18	natural	natural	ADJ
ajst-20185	18	19	selection	selection	NOUN
ajst-20185	18	20	[	[	X
ajst-20185	18	21	9	9	NUM
ajst-20185	18	22	]	]	PUNCT
ajst-20185	18	23	.	.	PUNCT
ajst-20185	19	1	these	these	DET
ajst-20185	19	2	variations	variation	NOUN
ajst-20185	19	3	may	may	AUX
ajst-20185	19	4	encompass	encompass	VERB
ajst-20185	19	5	various	various	ADJ
ajst-20185	19	6	aspects	aspect	NOUN
ajst-20185	19	7	,	,	PUNCT
ajst-20185	19	8	such	such	ADJ
ajst-20185	19	9	as	as	ADP
ajst-20185	19	10	improved	improve	VERB
ajst-20185	19	11	cell	cell	NOUN
ajst-20185	19	12	membrane	membrane	NOUN
ajst-20185	19	13	stability	stability	NOUN
ajst-20185	19	14	,	,	PUNCT
ajst-20185	19	15	optimized	optimize	VERB
ajst-20185	19	16	adjustment	adjustment	NOUN
ajst-20185	19	17	of	of	ADP
ajst-20185	19	18	metabolic	metabolic	NOUN
ajst-20185	19	19	pathways	pathway	NOUN
ajst-20185	19	20	,	,	PUNCT
ajst-20185	19	21	and	and	CCONJ
ajst-20185	19	22	the	the	DET
ajst-20185	19	23	production	production	NOUN
ajst-20185	19	24	of	of	ADP
ajst-20185	19	25	acid	acid	NOUN
ajst-20185	19	26	-	-	PUNCT
ajst-20185	19	27	resistant	resistant	ADJ
ajst-20185	19	28	enzymes	enzyme	NOUN
ajst-20185	19	29	[	[	X
ajst-20185	19	30	10	10	NUM
ajst-20185	19	31	]	]	PUNCT
ajst-20185	19	32	.	.	PUNCT
ajst-20185	20	1	this	this	DET
ajst-20185	20	2	study	study	NOUN
ajst-20185	20	3	aims	aim	VERB
ajst-20185	20	4	to	to	PART
ajst-20185	20	5	investigate	investigate	VERB
ajst-20185	20	6	the	the	DET
ajst-20185	20	7	gene	gene	NOUN
ajst-20185	20	8	expression	expression	NOUN
ajst-20185	20	9	changes	change	NOUN
ajst-20185	20	10	of	of	ADP
ajst-20185	20	11	bacillus	bacillus	NOUN
ajst-20185	20	12	subtilis	subtili	NOUN
ajst-20185	20	13	in	in	ADP
ajst-20185	20	14	a	a	DET
ajst-20185	20	15	low	low	ADJ
ajst-20185	20	16	-	-	PUNCT
ajst-20185	20	17	ph	ph	NOUN
ajst-20185	20	18	environment	environment	NOUN
ajst-20185	20	19	using	use	VERB
ajst-20185	20	20	an	an	DET
ajst-20185	20	21	experimental	experimental	ADJ
ajst-20185	20	22	scheme	scheme	NOUN
ajst-20185	20	23	designed	design	VERB
ajst-20185	20	24	for	for	ADP
ajst-20185	20	25	acid	acid	NOUN
ajst-20185	20	26	adaptation	adaptation	NOUN
ajst-20185	20	27	evolution	evolution	NOUN
ajst-20185	20	28	combined	combine	VERB
ajst-20185	20	29	with	with	ADP
ajst-20185	20	30	transcriptomics	transcriptomic	NOUN
ajst-20185	20	31	analysis	analysis	NOUN
ajst-20185	20	32	[	[	X
ajst-20185	20	33	11	11	NUM
ajst-20185	20	34	-	-	SYM
ajst-20185	20	35	13	13	NUM
ajst-20185	20	36	]	]	PUNCT
ajst-20185	20	37	.	.	PUNCT
ajst-20185	21	1	we	we	PRON
ajst-20185	21	2	expect	expect	VERB
ajst-20185	21	3	that	that	SCONJ
ajst-20185	21	4	this	this	DET
ajst-20185	21	5	research	research	NOUN
ajst-20185	21	6	will	will	AUX
ajst-20185	21	7	elucidate	elucidate	VERB
ajst-20185	21	8	its	its	PRON
ajst-20185	21	9	adaptive	adaptive	ADJ
ajst-20185	21	10	mechanisms	mechanism	NOUN
ajst-20185	21	11	in	in	ADP
ajst-20185	21	12	acidic	acidic	ADJ
ajst-20185	21	13	environments	environment	NOUN
ajst-20185	21	14	,	,	PUNCT
ajst-20185	21	15	offering	offer	VERB
ajst-20185	21	16	new	new	ADJ
ajst-20185	21	17	theoretical	theoretical	ADJ
ajst-20185	21	18	support	support	NOUN
ajst-20185	21	19	and	and	CCONJ
ajst-20185	21	20	practical	practical	ADJ
ajst-20185	21	21	guidance	guidance	NOUN
ajst-20185	21	22	for	for	ADP
ajst-20185	21	23	the	the	DET
ajst-20185	21	24	application	application	NOUN
ajst-20185	21	25	of	of	ADP
ajst-20185	21	26	microbiology	microbiology	NOUN
ajst-20185	21	27	in	in	ADP
ajst-20185	21	28	such	such	ADJ
ajst-20185	21	29	conditions	condition	NOUN
ajst-20185	21	30	.	.	PUNCT
ajst-20185	22	1	2	2	X
ajst-20185	22	2	.	.	X
ajst-20185	22	3	materials	material	NOUN
ajst-20185	22	4	and	and	CCONJ
ajst-20185	22	5	methods	method	NOUN
ajst-20185	22	6	2.1	2.1	NUM
ajst-20185	22	7	.	.	PUNCT
ajst-20185	23	1	strain	strain	NOUN
ajst-20185	23	2	and	and	CCONJ
ajst-20185	23	3	medium	medium	ADJ
ajst-20185	23	4	the	the	DET
ajst-20185	23	5	strain	strain	NOUN
ajst-20185	23	6	utilized	utilize	VERB
ajst-20185	23	7	in	in	ADP
ajst-20185	23	8	this	this	DET
ajst-20185	23	9	study	study	NOUN
ajst-20185	23	10	was	be	AUX
ajst-20185	23	11	bacillus	bacillus	NOUN
ajst-20185	23	12	subtilis	subtili	NOUN
ajst-20185	23	13	168	168	NUM
ajst-20185	23	14	,	,	PUNCT
ajst-20185	23	15	which	which	PRON
ajst-20185	23	16	had	have	AUX
ajst-20185	23	17	been	be	AUX
ajst-20185	23	18	maintained	maintain	VERB
ajst-20185	23	19	in	in	ADP
ajst-20185	23	20	the	the	DET
ajst-20185	23	21	laboratory	laboratory	NOUN
ajst-20185	23	22	.	.	PUNCT
ajst-20185	24	1	it	it	PRON
ajst-20185	24	2	was	be	AUX
ajst-20185	24	3	cultivated	cultivate	VERB
ajst-20185	24	4	and	and	CCONJ
ajst-20185	24	5	activated	activate	VERB
ajst-20185	24	6	in	in	ADP
ajst-20185	24	7	the	the	DET
ajst-20185	24	8	lb	lb	PRON
ajst-20185	24	9	medium	medium	ADJ
ajst-20185	24	10	and	and	CCONJ
ajst-20185	24	11	underwent	underwent	ADJ
ajst-20185	24	12	acid	acid	NOUN
ajst-20185	24	13	adaptation	adaptation	NOUN
ajst-20185	24	14	evolution	evolution	NOUN
ajst-20185	24	15	in	in	ADP
ajst-20185	24	16	the	the	DET
ajst-20185	24	17	m3	m3	PROPN
ajst-20185	24	18	g	g	PROPN
ajst-20185	24	19	medium	medium	NOUN
ajst-20185	24	20	.	.	PUNCT
ajst-20185	25	1	2.2	2.2	NUM
ajst-20185	25	2	.	.	PUNCT
ajst-20185	26	1	preparation	preparation	NOUN
ajst-20185	26	2	of	of	ADP
ajst-20185	26	3	acid	acid	ADJ
ajst-20185	26	4	adaptation	adaptation	NOUN
ajst-20185	26	5	evolution	evolution	NOUN
ajst-20185	26	6	medium	medium	NOUN
ajst-20185	26	7	and	and	CCONJ
ajst-20185	26	8	seed	seed	NOUN
ajst-20185	26	9	solution	solution	NOUN
ajst-20185	26	10	for	for	ADP
ajst-20185	26	11	the	the	DET
ajst-20185	26	12	acid	acid	NOUN
ajst-20185	26	13	adaptation	adaptation	NOUN
ajst-20185	26	14	evolution	evolution	NOUN
ajst-20185	26	15	experiment	experiment	NOUN
ajst-20185	26	16	,	,	PUNCT
ajst-20185	26	17	we	we	PRON
ajst-20185	26	18	prepared	prepare	VERB
ajst-20185	26	19	m3	m3	PROPN
ajst-20185	26	20	g	g	PROPN
ajst-20185	26	21	media	medium	NOUN
ajst-20185	26	22	with	with	ADP
ajst-20185	26	23	ph	ph	ADJ
ajst-20185	26	24	values	value	NOUN
ajst-20185	26	25	of	of	ADP
ajst-20185	26	26	4.5	4.5	NUM
ajst-20185	26	27	and	and	CCONJ
ajst-20185	26	28	7.0	7.0	NUM
ajst-20185	26	29	,	,	PUNCT
ajst-20185	26	30	respectively	respectively	ADV
ajst-20185	26	31	,	,	PUNCT
ajst-20185	26	32	and	and	CCONJ
ajst-20185	26	33	sterilized	sterilize	VERB
ajst-20185	26	34	them	they	PRON
ajst-20185	26	35	at	at	ADP
ajst-20185	26	36	115	115	NUM
ajst-20185	26	37	℃	℃	PROPN
ajst-20185	26	38	to	to	PART
ajst-20185	26	39	ensure	ensure	VERB
ajst-20185	26	40	aseptic	aseptic	ADJ
ajst-20185	26	41	conditions	condition	NOUN
ajst-20185	26	42	.	.	PUNCT
ajst-20185	27	1	simultaneously	simultaneously	ADV
ajst-20185	27	2	,	,	PUNCT
ajst-20185	27	3	lb	lb	DET
ajst-20185	27	4	medium	medium	NOUN
ajst-20185	27	5	with	with	ADP
ajst-20185	27	6	a	a	DET
ajst-20185	27	7	ph	ph	NOUN
ajst-20185	27	8	of	of	ADP
ajst-20185	27	9	7.0	7.0	NUM
ajst-20185	27	10	was	be	AUX
ajst-20185	27	11	also	also	ADV
ajst-20185	27	12	prepared	prepared	ADJ
ajst-20185	27	13	and	and	CCONJ
ajst-20185	27	14	sterilized	sterilize	VERB
ajst-20185	27	15	at	at	ADP
ajst-20185	27	16	120	120	NUM
ajst-20185	27	17	℃	℃	PROPN
ajst-20185	27	18	for	for	ADP
ajst-20185	27	19	subsequent	subsequent	ADJ
ajst-20185	27	20	strain	strain	NOUN
ajst-20185	27	21	activation	activation	NOUN
ajst-20185	27	22	.	.	PUNCT
ajst-20185	28	1	to	to	PART
ajst-20185	28	2	obtain	obtain	VERB
ajst-20185	28	3	the	the	DET
ajst-20185	28	4	seed	seed	NOUN
ajst-20185	28	5	solution	solution	NOUN
ajst-20185	28	6	for	for	ADP
ajst-20185	28	7	acid	acid	NOUN
ajst-20185	28	8	adaptation	adaptation	NOUN
ajst-20185	28	9	evolution	evolution	NOUN
ajst-20185	28	10	,	,	PUNCT
ajst-20185	28	11	a	a	DET
ajst-20185	28	12	small	small	ADJ
ajst-20185	28	13	amount	amount	NOUN
ajst-20185	28	14	of	of	ADP
ajst-20185	28	15	bacteria	bacteria	NOUN
ajst-20185	28	16	was	be	AUX
ajst-20185	28	17	extracted	extract	VERB
ajst-20185	28	18	from	from	ADP
ajst-20185	28	19	the	the	DET
ajst-20185	28	20	preserved	preserve	VERB
ajst-20185	28	21	bacillus	bacillus	NOUN
ajst-20185	28	22	subtilis	subtili	NOUN
ajst-20185	28	23	168	168	NUM
ajst-20185	28	24	strain	strain	NOUN
ajst-20185	28	25	and	and	CCONJ
ajst-20185	28	26	streaked	streak	VERB
ajst-20185	28	27	onto	onto	ADP
ajst-20185	28	28	a	a	DET
ajst-20185	28	29	solid	solid	ADJ
ajst-20185	28	30	lb	lb	NOUN
ajst-20185	28	31	plate	plate	NOUN
ajst-20185	28	32	for	for	ADP
ajst-20185	28	33	activation	activation	NOUN
ajst-20185	28	34	.	.	PUNCT
ajst-20185	29	1	the	the	DET
ajst-20185	29	2	plate	plate	NOUN
ajst-20185	29	3	was	be	AUX
ajst-20185	29	4	then	then	ADV
ajst-20185	29	5	incubated	incubate	VERB
ajst-20185	29	6	in	in	ADP
ajst-20185	29	7	a	a	DET
ajst-20185	29	8	constant	constant	ADJ
ajst-20185	29	9	temperature	temperature	NOUN
ajst-20185	29	10	incubator	incubator	NOUN
ajst-20185	29	11	at	at	ADP
ajst-20185	29	12	37	37	NUM
ajst-20185	29	13	℃	℃	PROPN
ajst-20185	29	14	for	for	ADP
ajst-20185	29	15	approximately	approximately	ADV
ajst-20185	29	16	10	10	NUM
ajst-20185	29	17	hours	hour	NOUN
ajst-20185	29	18	until	until	SCONJ
ajst-20185	29	19	distinct	distinct	ADJ
ajst-20185	29	20	single	single	ADJ
ajst-20185	29	21	colonies	colony	NOUN
ajst-20185	29	22	emerged	emerge	VERB
ajst-20185	29	23	.	.	PUNCT
ajst-20185	30	1	subsequently	subsequently	ADV
ajst-20185	30	2	,	,	PUNCT
ajst-20185	30	3	a	a	DET
ajst-20185	30	4	single	single	ADJ
ajst-20185	30	5	colony	colony	NOUN
ajst-20185	30	6	was	be	AUX
ajst-20185	30	7	selected	select	VERB
ajst-20185	30	8	from	from	ADP
ajst-20185	30	9	the	the	DET
ajst-20185	30	10	plate	plate	NOUN
ajst-20185	30	11	and	and	CCONJ
ajst-20185	30	12	inoculated	inoculate	VERB
ajst-20185	30	13	into	into	ADP
ajst-20185	30	14	a	a	DET
ajst-20185	30	15	conical	conical	ADJ
ajst-20185	30	16	flask	flask	NOUN
ajst-20185	30	17	containing	contain	VERB
ajst-20185	30	18	50ml	50ml	NOUN
ajst-20185	30	19	of	of	ADP
ajst-20185	30	20	fresh	fresh	ADJ
ajst-20185	30	21	,	,	PUNCT
ajst-20185	30	22	sterilized	sterilize	VERB
ajst-20185	30	23	lb	lb	DET
ajst-20185	30	24	liquid	liquid	ADJ
ajst-20185	30	25	medium	medium	NOUN
ajst-20185	30	26	.	.	PUNCT
ajst-20185	31	1	the	the	DET
ajst-20185	31	2	culture	culture	NOUN
ajst-20185	31	3	was	be	AUX
ajst-20185	31	4	then	then	ADV
ajst-20185	31	5	incubated	incubate	VERB
ajst-20185	31	6	at	at	ADP
ajst-20185	31	7	37	37	NUM
ajst-20185	31	8	℃	℃	PROPN
ajst-20185	31	9	with	with	ADP
ajst-20185	31	10	shaking	shake	VERB
ajst-20185	31	11	at	at	ADP
ajst-20185	31	12	200	200	NUM
ajst-20185	31	13	rpm	rpm	NOUN
ajst-20185	31	14	/	/	SYM
ajst-20185	31	15	min	min	PROPN
ajst-20185	31	16	.	.	NOUN
ajst-20185	31	17	after	after	ADP
ajst-20185	31	18	10	10	NUM
ajst-20185	31	19	-	-	SYM
ajst-20185	31	20	12	12	NUM
ajst-20185	31	21	hours	hour	NOUN
ajst-20185	31	22	of	of	ADP
ajst-20185	31	23	cultivation	cultivation	NOUN
ajst-20185	31	24	,	,	PUNCT
ajst-20185	31	25	the	the	DET
ajst-20185	31	26	strain	strain	NOUN
ajst-20185	31	27	activation	activation	NOUN
ajst-20185	31	28	process	process	NOUN
ajst-20185	31	29	was	be	AUX
ajst-20185	31	30	completed	complete	VERB
ajst-20185	31	31	.	.	PUNCT
ajst-20185	32	1	subsequently	subsequently	ADV
ajst-20185	32	2	,	,	PUNCT
ajst-20185	32	3	1	1	NUM
ajst-20185	32	4	ml	ml	NOUN
ajst-20185	32	5	of	of	ADP
ajst-20185	32	6	the	the	DET
ajst-20185	32	7	activated	activated	ADJ
ajst-20185	32	8	bacterial	bacterial	ADJ
ajst-20185	32	9	solution	solution	NOUN
ajst-20185	32	10	was	be	AUX
ajst-20185	32	11	inoculated	inoculate	VERB
ajst-20185	32	12	into	into	ADP
ajst-20185	32	13	a	a	DET
ajst-20185	32	14	conical	conical	ADJ
ajst-20185	32	15	flask	flask	NOUN
ajst-20185	32	16	containing	contain	VERB
ajst-20185	32	17	50	50	NUM
ajst-20185	32	18	ml	ml	NOUN
ajst-20185	32	19	of	of	ADP
ajst-20185	32	20	ph	ph	ADJ
ajst-20185	32	21	7.0	7.0	NUM
ajst-20185	32	22	m3	m3	PROPN
ajst-20185	32	23	g	g	NOUN
ajst-20185	32	24	liquid	liquid	ADJ
ajst-20185	32	25	medium	medium	NOUN
ajst-20185	32	26	and	and	CCONJ
ajst-20185	32	27	cultured	cultured	ADJ
ajst-20185	32	28	under	under	ADP
ajst-20185	32	29	identical	identical	ADJ
ajst-20185	32	30	conditions	condition	NOUN
ajst-20185	32	31	(	(	PUNCT
ajst-20185	32	32	37	37	NUM
ajst-20185	32	33	℃	℃	PROPN
ajst-20185	32	34	,	,	PUNCT
ajst-20185	32	35	200	200	NUM
ajst-20185	32	36	rpm	rpm	NOUN
ajst-20185	32	37	/	/	SYM
ajst-20185	32	38	min	min	NOUN
ajst-20185	32	39	)	)	PUNCT
ajst-20185	32	40	.	.	PUNCT
ajst-20185	33	1	following	follow	VERB
ajst-20185	33	2	an	an	DET
ajst-20185	33	3	incubation	incubation	NOUN
ajst-20185	33	4	period	period	NOUN
ajst-20185	33	5	of	of	ADP
ajst-20185	33	6	1012	1012	NUM
ajst-20185	33	7	hours	hour	NOUN
ajst-20185	33	8	,	,	PUNCT
ajst-20185	33	9	the	the	DET
ajst-20185	33	10	seed	seed	NOUN
ajst-20185	33	11	solution	solution	NOUN
ajst-20185	33	12	for	for	ADP
ajst-20185	33	13	acid	acid	NOUN
ajst-20185	33	14	adaptation	adaptation	NOUN
ajst-20185	33	15	evolution	evolution	NOUN
ajst-20185	33	16	was	be	AUX
ajst-20185	33	17	obtained	obtain	VERB
ajst-20185	33	18	.	.	PUNCT
ajst-20185	34	1	2.3	2.3	NUM
ajst-20185	34	2	.	.	PUNCT
ajst-20185	35	1	acid	acid	NOUN
ajst-20185	35	2	adaptation	adaptation	NOUN
ajst-20185	35	3	evolution	evolution	NOUN
ajst-20185	35	4	in	in	ADP
ajst-20185	35	5	order	order	NOUN
ajst-20185	35	6	to	to	PART
ajst-20185	35	7	investigate	investigate	VERB
ajst-20185	35	8	the	the	DET
ajst-20185	35	9	adaptive	adaptive	ADJ
ajst-20185	35	10	evolution	evolution	NOUN
ajst-20185	35	11	in	in	ADP
ajst-20185	35	12	acidic	acidic	ADJ
ajst-20185	35	13	environments	environment	NOUN
ajst-20185	35	14	,	,	PUNCT
ajst-20185	35	15	we	we	PRON
ajst-20185	35	16	developed	develop	VERB
ajst-20185	35	17	and	and	CCONJ
ajst-20185	35	18	executed	execute	VERB
ajst-20185	35	19	a	a	DET
ajst-20185	35	20	comprehensive	comprehensive	ADJ
ajst-20185	35	21	acid	acid	NOUN
ajst-20185	35	22	adaptation	adaptation	NOUN
ajst-20185	35	23	experiment	experiment	NOUN
ajst-20185	35	24	.	.	PUNCT
ajst-20185	36	1	the	the	DET
ajst-20185	36	2	experimental	experimental	ADJ
ajst-20185	36	3	protocol	protocol	NOUN
ajst-20185	36	4	was	be	AUX
ajst-20185	36	5	as	as	SCONJ
ajst-20185	36	6	follows	follow	VERB
ajst-20185	36	7	:	:	PUNCT
ajst-20185	36	8	during	during	ADP
ajst-20185	36	9	the	the	DET
ajst-20185	36	10	initial	initial	ADJ
ajst-20185	36	11	adaptation	adaptation	NOUN
ajst-20185	36	12	phase	phase	NOUN
ajst-20185	36	13	,	,	PUNCT
ajst-20185	36	14	we	we	PRON
ajst-20185	36	15	evenly	evenly	ADV
ajst-20185	36	16	distributed	distribute	VERB
ajst-20185	36	17	a	a	DET
ajst-20185	36	18	1ml	1ml	ADJ
ajst-20185	36	19	inoculum	inoculum	NOUN
ajst-20185	36	20	of	of	ADP
ajst-20185	36	21	the	the	DET
ajst-20185	36	22	seed	seed	NOUN
ajst-20185	36	23	solution	solution	NOUN
ajst-20185	36	24	into	into	ADP
ajst-20185	36	25	nine	nine	NUM
ajst-20185	36	26	sterilized	sterilize	VERB
ajst-20185	36	27	conical	conical	NOUN
ajst-20185	36	28	flasks	flask	NOUN
ajst-20185	36	29	containing	contain	VERB
ajst-20185	36	30	m3	m3	PROPN
ajst-20185	36	31	g	g	PROPN
ajst-20185	36	32	medium	medium	NOUN
ajst-20185	36	33	at	at	ADP
ajst-20185	36	34	ph	ph	PROPN
ajst-20185	36	35	7.0	7.0	NUM
ajst-20185	36	36	.	.	PUNCT
ajst-20185	37	1	these	these	DET
ajst-20185	37	2	flasks	flask	NOUN
ajst-20185	37	3	were	be	AUX
ajst-20185	37	4	56	56	NUM
ajst-20185	37	5	then	then	ADV
ajst-20185	37	6	incubated	incubate	VERB
ajst-20185	37	7	in	in	ADP
ajst-20185	37	8	a	a	DET
ajst-20185	37	9	constant	constant	ADJ
ajst-20185	37	10	temperature	temperature	NOUN
ajst-20185	37	11	shaker	shaker	NOUN
ajst-20185	37	12	at	at	ADP
ajst-20185	37	13	37	37	NUM
ajst-20185	37	14	℃	℃	PROPN
ajst-20185	37	15	and	and	CCONJ
ajst-20185	37	16	200	200	NUM
ajst-20185	37	17	rpm	rpm	NOUN
ajst-20185	37	18	/	/	SYM
ajst-20185	37	19	min	min	NOUN
ajst-20185	37	20	for	for	ADP
ajst-20185	37	21	10	10	NUM
ajst-20185	37	22	to	to	PART
ajst-20185	37	23	12	12	NUM
ajst-20185	37	24	hours	hour	NOUN
ajst-20185	37	25	until	until	ADP
ajst-20185	37	26	reaching	reach	VERB
ajst-20185	37	27	an	an	DET
ajst-20185	37	28	optical	optical	ADJ
ajst-20185	37	29	density	density	NOUN
ajst-20185	37	30	(	(	PUNCT
ajst-20185	37	31	od600	od600	NOUN
ajst-20185	37	32	)	)	PUNCT
ajst-20185	37	33	of	of	ADP
ajst-20185	37	34	approximately	approximately	ADV
ajst-20185	37	35	4	4	NUM
ajst-20185	37	36	,	,	PUNCT
ajst-20185	37	37	indicating	indicate	VERB
ajst-20185	37	38	the	the	DET
ajst-20185	37	39	attainment	attainment	NOUN
ajst-20185	37	40	of	of	ADP
ajst-20185	37	41	a	a	DET
ajst-20185	37	42	particular	particular	ADJ
ajst-20185	37	43	bacterial	bacterial	ADJ
ajst-20185	37	44	concentration	concentration	NOUN
ajst-20185	37	45	.	.	PUNCT
ajst-20185	38	1	subsequently	subsequently	ADV
ajst-20185	38	2	,	,	PUNCT
ajst-20185	38	3	we	we	PRON
ajst-20185	38	4	transferred	transfer	VERB
ajst-20185	38	5	80ml	80ml	NOUN
ajst-20185	38	6	of	of	ADP
ajst-20185	38	7	culture	culture	NOUN
ajst-20185	38	8	from	from	ADP
ajst-20185	38	9	each	each	DET
ajst-20185	38	10	flask	flask	NOUN
ajst-20185	38	11	into	into	ADP
ajst-20185	38	12	new	new	ADJ
ajst-20185	38	13	conical	conical	ADJ
ajst-20185	38	14	flasks	flask	NOUN
ajst-20185	38	15	containing	contain	VERB
ajst-20185	38	16	20ml	20ml	NOUN
ajst-20185	38	17	of	of	ADP
ajst-20185	38	18	m3	m3	PROPN
ajst-20185	38	19	g	g	PROPN
ajst-20185	38	20	medium	medium	NOUN
ajst-20185	38	21	at	at	ADP
ajst-20185	38	22	ph	ph	PROPN
ajst-20185	38	23	4.5	4.5	NUM
ajst-20185	38	24	,	,	PUNCT
ajst-20185	38	25	labeled	label	VERB
ajst-20185	38	26	a1	a1	NOUN
ajst-20185	38	27	to	to	ADP
ajst-20185	38	28	a9	a9	NOUN
ajst-20185	38	29	,	,	PUNCT
ajst-20185	38	30	with	with	ADP
ajst-20185	38	31	the	the	DET
ajst-20185	38	32	purpose	purpose	NOUN
ajst-20185	38	33	of	of	ADP
ajst-20185	38	34	exposing	expose	VERB
ajst-20185	38	35	the	the	DET
ajst-20185	38	36	strain	strain	NOUN
ajst-20185	38	37	to	to	ADP
ajst-20185	38	38	an	an	DET
ajst-20185	38	39	acidic	acidic	ADJ
ajst-20185	38	40	environment	environment	NOUN
ajst-20185	38	41	for	for	ADP
ajst-20185	38	42	initial	initial	ADJ
ajst-20185	38	43	adaptation	adaptation	NOUN
ajst-20185	38	44	.	.	PUNCT
ajst-20185	39	1	in	in	ADP
ajst-20185	39	2	the	the	DET
ajst-20185	39	3	second	second	ADJ
ajst-20185	39	4	round	round	NOUN
ajst-20185	39	5	of	of	ADP
ajst-20185	39	6	evolution	evolution	NOUN
ajst-20185	39	7	,	,	PUNCT
ajst-20185	39	8	we	we	PRON
ajst-20185	39	9	continued	continue	VERB
ajst-20185	39	10	to	to	PART
ajst-20185	39	11	culture	culture	VERB
ajst-20185	39	12	the	the	DET
ajst-20185	39	13	bacterial	bacterial	ADJ
ajst-20185	39	14	solutions	solution	NOUN
ajst-20185	39	15	in	in	ADP
ajst-20185	39	16	flasks	flask	NOUN
ajst-20185	39	17	a1	a1	VERB
ajst-20185	39	18	to	to	ADP
ajst-20185	39	19	a9	a9	NOUN
ajst-20185	39	20	until	until	ADP
ajst-20185	39	21	reaching	reach	VERB
ajst-20185	39	22	an	an	DET
ajst-20185	39	23	od600	od600	NOUN
ajst-20185	39	24	of	of	ADP
ajst-20185	39	25	approximately	approximately	ADV
ajst-20185	39	26	4	4	NUM
ajst-20185	39	27	.	.	PUNCT
ajst-20185	39	28	subsequently	subsequently	ADV
ajst-20185	39	29	,	,	PUNCT
ajst-20185	39	30	we	we	PRON
ajst-20185	39	31	selected	select	VERB
ajst-20185	39	32	the	the	DET
ajst-20185	39	33	six	six	NUM
ajst-20185	39	34	flasks	flask	NOUN
ajst-20185	39	35	with	with	ADP
ajst-20185	39	36	the	the	DET
ajst-20185	39	37	highest	high	ADJ
ajst-20185	39	38	growth	growth	NOUN
ajst-20185	39	39	rates	rate	NOUN
ajst-20185	39	40	and	and	CCONJ
ajst-20185	39	41	transferred	transfer	VERB
ajst-20185	39	42	60ml	60ml	NOUN
ajst-20185	39	43	of	of	ADP
ajst-20185	39	44	culture	culture	NOUN
ajst-20185	39	45	from	from	ADP
ajst-20185	39	46	each	each	PRON
ajst-20185	39	47	into	into	ADP
ajst-20185	39	48	new	new	ADJ
ajst-20185	39	49	conical	conical	ADJ
ajst-20185	39	50	flasks	flask	NOUN
ajst-20185	39	51	containing	contain	VERB
ajst-20185	39	52	40ml	40ml	NOUN
ajst-20185	39	53	of	of	ADP
ajst-20185	39	54	fresh	fresh	ADJ
ajst-20185	39	55	m3	m3	PROPN
ajst-20185	39	56	g	g	PROPN
ajst-20185	39	57	medium	medium	NOUN
ajst-20185	39	58	at	at	ADP
ajst-20185	39	59	ph	ph	PROPN
ajst-20185	39	60	4.5	4.5	NUM
ajst-20185	39	61	,	,	PUNCT
ajst-20185	39	62	designated	designate	VERB
ajst-20185	39	63	as	as	ADP
ajst-20185	39	64	the	the	DET
ajst-20185	39	65	b	b	PROPN
ajst-20185	39	66	series	series	NOUN
ajst-20185	39	67	.	.	PUNCT
ajst-20185	40	1	this	this	DET
ajst-20185	40	2	step	step	NOUN
ajst-20185	40	3	aimed	aim	VERB
ajst-20185	40	4	to	to	PART
ajst-20185	40	5	further	far	ADV
ajst-20185	40	6	enhance	enhance	VERB
ajst-20185	40	7	the	the	DET
ajst-20185	40	8	adaptability	adaptability	NOUN
ajst-20185	40	9	of	of	ADP
ajst-20185	40	10	the	the	DET
ajst-20185	40	11	strain	strain	NOUN
ajst-20185	40	12	to	to	ADP
ajst-20185	40	13	acidic	acidic	ADJ
ajst-20185	40	14	environments	environment	NOUN
ajst-20185	40	15	by	by	ADP
ajst-20185	40	16	selectively	selectively	ADV
ajst-20185	40	17	cultivating	cultivate	VERB
ajst-20185	40	18	more	more	ADV
ajst-20185	40	19	resilient	resilient	ADJ
ajst-20185	40	20	strains	strain	NOUN
ajst-20185	40	21	.	.	PUNCT
ajst-20185	41	1	the	the	DET
ajst-20185	41	2	third	third	ADJ
ajst-20185	41	3	round	round	NOUN
ajst-20185	41	4	of	of	ADP
ajst-20185	41	5	evolution	evolution	NOUN
ajst-20185	41	6	was	be	AUX
ajst-20185	41	7	conducted	conduct	VERB
ajst-20185	41	8	with	with	ADP
ajst-20185	41	9	even	even	ADV
ajst-20185	41	10	greater	great	ADJ
ajst-20185	41	11	stringency	stringency	NOUN
ajst-20185	41	12	.	.	PUNCT
ajst-20185	42	1	when	when	SCONJ
ajst-20185	42	2	the	the	DET
ajst-20185	42	3	od600	od600	ADJ
ajst-20185	42	4	values	value	NOUN
ajst-20185	42	5	of	of	ADP
ajst-20185	42	6	the	the	DET
ajst-20185	42	7	b	b	PROPN
ajst-20185	42	8	series	series	NOUN
ajst-20185	42	9	cultures	culture	NOUN
ajst-20185	42	10	approached	approach	VERB
ajst-20185	42	11	4	4	NUM
ajst-20185	42	12	,	,	PUNCT
ajst-20185	42	13	we	we	PRON
ajst-20185	42	14	once	once	ADV
ajst-20185	42	15	again	again	ADV
ajst-20185	42	16	selected	select	VERB
ajst-20185	42	17	the	the	DET
ajst-20185	42	18	bacterial	bacterial	ADJ
ajst-20185	42	19	solutions	solution	NOUN
ajst-20185	42	20	exhibiting	exhibit	VERB
ajst-20185	42	21	the	the	DET
ajst-20185	42	22	highest	high	ADJ
ajst-20185	42	23	growth	growth	NOUN
ajst-20185	42	24	rates	rate	NOUN
ajst-20185	42	25	and	and	CCONJ
ajst-20185	42	26	transferred	transfer	VERB
ajst-20185	42	27	40ml	40ml	NOUN
ajst-20185	42	28	of	of	ADP
ajst-20185	42	29	each	each	PRON
ajst-20185	42	30	into	into	ADP
ajst-20185	42	31	new	new	ADJ
ajst-20185	42	32	conical	conical	ADJ
ajst-20185	42	33	flasks	flask	NOUN
ajst-20185	42	34	containing	contain	VERB
ajst-20185	42	35	60ml	60ml	NOUN
ajst-20185	42	36	of	of	ADP
ajst-20185	42	37	fresh	fresh	ADJ
ajst-20185	42	38	m3	m3	PROPN
ajst-20185	42	39	g	g	PROPN
ajst-20185	42	40	medium	medium	NOUN
ajst-20185	42	41	at	at	ADP
ajst-20185	42	42	ph	ph	PROPN
ajst-20185	42	43	4.5	4.5	NUM
ajst-20185	42	44	,	,	PUNCT
ajst-20185	42	45	designated	designate	VERB
ajst-20185	42	46	as	as	ADP
ajst-20185	42	47	the	the	DET
ajst-20185	42	48	c	c	PROPN
ajst-20185	42	49	series	series	NOUN
ajst-20185	42	50	.	.	PUNCT
ajst-20185	43	1	this	this	DET
ajst-20185	43	2	procedure	procedure	NOUN
ajst-20185	43	3	facilitated	facilitate	VERB
ajst-20185	43	4	the	the	DET
ajst-20185	43	5	ongoing	ongoing	ADJ
ajst-20185	43	6	selection	selection	NOUN
ajst-20185	43	7	of	of	ADP
ajst-20185	43	8	strains	strain	NOUN
ajst-20185	43	9	with	with	ADP
ajst-20185	43	10	enhanced	enhanced	ADJ
ajst-20185	43	11	adaptability	adaptability	NOUN
ajst-20185	43	12	to	to	ADP
ajst-20185	43	13	acidic	acidic	ADJ
ajst-20185	43	14	environments	environment	NOUN
ajst-20185	43	15	,	,	PUNCT
ajst-20185	43	16	progressively	progressively	ADV
ajst-20185	43	17	elevating	elevate	VERB
ajst-20185	43	18	their	their	PRON
ajst-20185	43	19	level	level	NOUN
ajst-20185	43	20	of	of	ADP
ajst-20185	43	21	adaptation	adaptation	NOUN
ajst-20185	43	22	.	.	PUNCT
ajst-20185	44	1	in	in	ADP
ajst-20185	44	2	the	the	DET
ajst-20185	44	3	final	final	ADJ
ajst-20185	44	4	phase	phase	NOUN
ajst-20185	44	5	of	of	ADP
ajst-20185	44	6	adaptation	adaptation	NOUN
ajst-20185	44	7	evolution	evolution	NOUN
ajst-20185	44	8	,	,	PUNCT
ajst-20185	44	9	we	we	PRON
ajst-20185	44	10	selected	select	VERB
ajst-20185	44	11	the	the	DET
ajst-20185	44	12	three	three	NUM
ajst-20185	44	13	most	most	ADV
ajst-20185	44	14	rapidly	rapidly	ADV
ajst-20185	44	15	proliferating	proliferate	VERB
ajst-20185	44	16	cultures	culture	NOUN
ajst-20185	44	17	from	from	ADP
ajst-20185	44	18	the	the	DET
ajst-20185	44	19	c	c	PROPN
ajst-20185	44	20	series	series	NOUN
ajst-20185	44	21	and	and	CCONJ
ajst-20185	44	22	transferred	transfer	VERB
ajst-20185	44	23	20ml	20ml	NOUN
ajst-20185	44	24	of	of	ADP
ajst-20185	44	25	each	each	PRON
ajst-20185	44	26	into	into	ADP
ajst-20185	44	27	new	new	ADJ
ajst-20185	44	28	conical	conical	ADJ
ajst-20185	44	29	flasks	flask	NOUN
ajst-20185	44	30	containing	contain	VERB
ajst-20185	44	31	80ml	80ml	NOUN
ajst-20185	44	32	of	of	ADP
ajst-20185	44	33	m3	m3	PROPN
ajst-20185	44	34	g	g	PROPN
ajst-20185	44	35	medium	medium	NOUN
ajst-20185	44	36	at	at	ADP
ajst-20185	44	37	ph	ph	PROPN
ajst-20185	44	38	4.5	4.5	NUM
ajst-20185	44	39	,	,	PUNCT
ajst-20185	44	40	designated	designate	VERB
ajst-20185	44	41	as	as	ADP
ajst-20185	44	42	the	the	DET
ajst-20185	44	43	d	d	PROPN
ajst-20185	44	44	series	series	NOUN
ajst-20185	44	45	.	.	PUNCT
ajst-20185	45	1	these	these	PRON
ajst-20185	45	2	were	be	AUX
ajst-20185	45	3	cultivated	cultivate	VERB
ajst-20185	45	4	under	under	ADP
ajst-20185	45	5	consistent	consistent	ADJ
ajst-20185	45	6	temperature	temperature	NOUN
ajst-20185	45	7	shaking	shake	VERB
ajst-20185	45	8	conditions	condition	NOUN
ajst-20185	45	9	until	until	ADP
ajst-20185	45	10	reaching	reach	VERB
ajst-20185	45	11	an	an	DET
ajst-20185	45	12	od600	od600	NOUN
ajst-20185	45	13	of	of	ADP
ajst-20185	45	14	approximately	approximately	ADV
ajst-20185	45	15	4	4	NUM
ajst-20185	45	16	,	,	PUNCT
ajst-20185	45	17	signifying	signify	VERB
ajst-20185	45	18	the	the	DET
ajst-20185	45	19	completion	completion	NOUN
ajst-20185	45	20	of	of	ADP
ajst-20185	45	21	the	the	DET
ajst-20185	45	22	low	low	ADJ
ajst-20185	45	23	ph	ph	NOUN
ajst-20185	45	24	adaptation	adaptation	NOUN
ajst-20185	45	25	evolution	evolution	NOUN
ajst-20185	45	26	process	process	NOUN
ajst-20185	45	27	for	for	ADP
ajst-20185	45	28	the	the	DET
ajst-20185	45	29	strain	strain	NOUN
ajst-20185	45	30	.	.	PUNCT
ajst-20185	46	1	to	to	PART
ajst-20185	46	2	assess	assess	VERB
ajst-20185	46	3	the	the	DET
ajst-20185	46	4	efficacy	efficacy	NOUN
ajst-20185	46	5	of	of	ADP
ajst-20185	46	6	low	low	ADJ
ajst-20185	46	7	ph	ph	ADJ
ajst-20185	46	8	adaptation	adaptation	NOUN
ajst-20185	46	9	evolution	evolution	NOUN
ajst-20185	46	10	,	,	PUNCT
ajst-20185	46	11	we	we	PRON
ajst-20185	46	12	selected	select	VERB
ajst-20185	46	13	the	the	DET
ajst-20185	46	14	fastest	fast	ADV
ajst-20185	46	15	-	-	PUNCT
ajst-20185	46	16	growing	grow	VERB
ajst-20185	46	17	cohort	cohort	NOUN
ajst-20185	46	18	from	from	ADP
ajst-20185	46	19	the	the	DET
ajst-20185	46	20	d	d	PROPN
ajst-20185	46	21	series	series	NOUN
ajst-20185	46	22	as	as	ADP
ajst-20185	46	23	the	the	DET
ajst-20185	46	24	experimental	experimental	ADJ
ajst-20185	46	25	group	group	NOUN
ajst-20185	46	26	and	and	CCONJ
ajst-20185	46	27	inoculated	inoculate	VERB
ajst-20185	46	28	it	it	PRON
ajst-20185	46	29	into	into	ADP
ajst-20185	46	30	a	a	DET
ajst-20185	46	31	new	new	ADJ
ajst-20185	46	32	ph	ph	ADJ
ajst-20185	46	33	4.5	4.5	NUM
ajst-20185	46	34	m3	m3	PROPN
ajst-20185	46	35	g	g	PROPN
ajst-20185	46	36	medium	medium	NOUN
ajst-20185	46	37	.	.	PUNCT
ajst-20185	47	1	concurrently	concurrently	ADV
ajst-20185	47	2	,	,	PUNCT
ajst-20185	47	3	an	an	DET
ajst-20185	47	4	equivalent	equivalent	ADJ
ajst-20185	47	5	amount	amount	NOUN
ajst-20185	47	6	of	of	ADP
ajst-20185	47	7	wild	wild	ADJ
ajst-20185	47	8	-	-	PUNCT
ajst-20185	47	9	type	type	NOUN
ajst-20185	47	10	strain	strain	NOUN
ajst-20185	47	11	was	be	AUX
ajst-20185	47	12	inoculated	inoculate	VERB
ajst-20185	47	13	as	as	ADP
ajst-20185	47	14	a	a	DET
ajst-20185	47	15	control	control	NOUN
ajst-20185	47	16	group	group	NOUN
ajst-20185	47	17	.	.	PUNCT
ajst-20185	48	1	by	by	ADP
ajst-20185	48	2	monitoring	monitor	VERB
ajst-20185	48	3	growth	growth	NOUN
ajst-20185	48	4	curves	curve	NOUN
ajst-20185	48	5	over	over	ADP
ajst-20185	48	6	a	a	DET
ajst-20185	48	7	12	12	NUM
ajst-20185	48	8	-	-	PUNCT
ajst-20185	48	9	hour	hour	NOUN
ajst-20185	48	10	period	period	NOUN
ajst-20185	48	11	,	,	PUNCT
ajst-20185	48	12	we	we	PRON
ajst-20185	48	13	confirmed	confirm	VERB
ajst-20185	48	14	the	the	DET
ajst-20185	48	15	success	success	NOUN
ajst-20185	48	16	of	of	ADP
ajst-20185	48	17	low	low	ADJ
ajst-20185	48	18	acid	acid	NOUN
ajst-20185	48	19	adaptation	adaptation	NOUN
ajst-20185	48	20	evolution	evolution	NOUN
ajst-20185	48	21	.	.	PUNCT
ajst-20185	49	1	2.4	2.4	NUM
ajst-20185	49	2	.	.	PUNCT
ajst-20185	50	1	rna	rna	NOUN
ajst-20185	50	2	extraction	extraction	NOUN
ajst-20185	50	3	and	and	CCONJ
ajst-20185	50	4	transcriptome	transcriptome	ADJ
ajst-20185	50	5	sequencing	sequence	VERB
ajst-20185	50	6	samples	sample	NOUN
ajst-20185	50	7	of	of	ADP
ajst-20185	50	8	the	the	DET
ajst-20185	50	9	adaptively	adaptively	ADV
ajst-20185	50	10	evolved	evolve	VERB
ajst-20185	50	11	bacterial	bacterial	ADJ
ajst-20185	50	12	solution	solution	NOUN
ajst-20185	50	13	were	be	AUX
ajst-20185	50	14	collected	collect	VERB
ajst-20185	50	15	and	and	CCONJ
ajst-20185	50	16	transferred	transfer	VERB
ajst-20185	50	17	to	to	AUX
ajst-20185	50	18	centrifuge	centrifuge	NOUN
ajst-20185	50	19	tubes	tube	NOUN
ajst-20185	50	20	.	.	PUNCT
ajst-20185	51	1	the	the	DET
ajst-20185	51	2	bacterial	bacterial	ADJ
ajst-20185	51	3	cells	cell	NOUN
ajst-20185	51	4	were	be	AUX
ajst-20185	51	5	then	then	ADV
ajst-20185	51	6	fully	fully	ADV
ajst-20185	51	7	precipitated	precipitate	VERB
ajst-20185	51	8	at	at	ADP
ajst-20185	51	9	4	4	NUM
ajst-20185	51	10	℃	℃	PROPN
ajst-20185	51	11	by	by	ADP
ajst-20185	51	12	centrifuging	centrifuge	VERB
ajst-20185	51	13	at	at	ADP
ajst-20185	51	14	a	a	DET
ajst-20185	51	15	speed	speed	NOUN
ajst-20185	51	16	of	of	ADP
ajst-20185	51	17	10,000	10,000	NUM
ajst-20185	51	18	rpm	rpm	NOUN
ajst-20185	51	19	,	,	PUNCT
ajst-20185	51	20	followed	follow	VERB
ajst-20185	51	21	by	by	ADP
ajst-20185	51	22	removal	removal	NOUN
ajst-20185	51	23	of	of	ADP
ajst-20185	51	24	the	the	DET
ajst-20185	51	25	supernatant	supernatant	NOUN
ajst-20185	51	26	.	.	PUNCT
ajst-20185	52	1	subsequently	subsequently	ADV
ajst-20185	52	2	,	,	PUNCT
ajst-20185	52	3	the	the	DET
ajst-20185	52	4	precipitated	precipitate	VERB
ajst-20185	52	5	bacterial	bacterial	ADJ
ajst-20185	52	6	cells	cell	NOUN
ajst-20185	52	7	were	be	AUX
ajst-20185	52	8	rapidly	rapidly	ADV
ajst-20185	52	9	frozen	freeze	VERB
ajst-20185	52	10	in	in	ADP
ajst-20185	52	11	liquid	liquid	ADJ
ajst-20185	52	12	nitrogen	nitrogen	NOUN
ajst-20185	52	13	for	for	ADP
ajst-20185	52	14	15	15	NUM
ajst-20185	52	15	minutes	minute	NOUN
ajst-20185	52	16	to	to	PART
ajst-20185	52	17	stabilize	stabilize	VERB
ajst-20185	52	18	the	the	DET
ajst-20185	52	19	rna	rna	NOUN
ajst-20185	52	20	and	and	CCONJ
ajst-20185	52	21	prevent	prevent	VERB
ajst-20185	52	22	degradation	degradation	NOUN
ajst-20185	52	23	.	.	PUNCT
ajst-20185	53	1	total	total	ADJ
ajst-20185	53	2	rna	rna	NOUN
ajst-20185	53	3	extraction	extraction	NOUN
ajst-20185	53	4	was	be	AUX
ajst-20185	53	5	performed	perform	VERB
ajst-20185	53	6	,	,	PUNCT
ajst-20185	53	7	and	and	CCONJ
ajst-20185	53	8	transcriptome	transcriptome	ADJ
ajst-20185	53	9	sequencing	sequencing	NOUN
ajst-20185	53	10	was	be	AUX
ajst-20185	53	11	carried	carry	VERB
ajst-20185	53	12	out	out	ADP
ajst-20185	53	13	using	use	VERB
ajst-20185	53	14	the	the	DET
ajst-20185	53	15	illumina	illumina	ADJ
ajst-20185	53	16	sequencing	sequence	VERB
ajst-20185	53	17	platform	platform	NOUN
ajst-20185	53	18	.	.	PUNCT
ajst-20185	54	1	rigorous	rigorous	ADJ
ajst-20185	54	2	quality	quality	NOUN
ajst-20185	54	3	control	control	NOUN
ajst-20185	54	4	and	and	CCONJ
ajst-20185	54	5	preprocessing	preprocessing	NOUN
ajst-20185	54	6	of	of	ADP
ajst-20185	54	7	the	the	DET
ajst-20185	54	8	sequencing	sequence	VERB
ajst-20185	54	9	data	datum	NOUN
ajst-20185	54	10	ensured	ensure	VERB
ajst-20185	54	11	accurate	accurate	ADJ
ajst-20185	54	12	results	result	NOUN
ajst-20185	54	13	for	for	ADP
ajst-20185	54	14	subsequent	subsequent	ADJ
ajst-20185	54	15	gene	gene	NOUN
ajst-20185	54	16	expression	expression	NOUN
ajst-20185	54	17	analysis	analysis	NOUN
ajst-20185	54	18	.	.	PUNCT
ajst-20185	55	1	2.5	2.5	NUM
ajst-20185	55	2	.	.	PUNCT
ajst-20185	56	1	transcriptome	transcriptome	PROPN
ajst-20185	56	2	data	datum	NOUN
ajst-20185	56	3	analysis	analysis	NOUN
ajst-20185	56	4	a	a	DET
ajst-20185	56	5	comprehensive	comprehensive	ADJ
ajst-20185	56	6	bioinformatics	bioinformatics	NOUN
ajst-20185	56	7	analysis	analysis	NOUN
ajst-20185	56	8	was	be	AUX
ajst-20185	56	9	conducted	conduct	VERB
ajst-20185	56	10	on	on	ADP
ajst-20185	56	11	the	the	DET
ajst-20185	56	12	transcriptome	transcriptome	NOUN
ajst-20185	56	13	data	datum	NOUN
ajst-20185	56	14	obtained	obtain	VERB
ajst-20185	56	15	from	from	ADP
ajst-20185	56	16	sequencing	sequence	VERB
ajst-20185	56	17	.	.	PUNCT
ajst-20185	57	1	initially	initially	ADV
ajst-20185	57	2	,	,	PUNCT
ajst-20185	57	3	differentially	differentially	ADV
ajst-20185	57	4	expressed	express	VERB
ajst-20185	57	5	genes	gene	NOUN
ajst-20185	57	6	(	(	PUNCT
ajst-20185	57	7	degs	deg	NOUN
ajst-20185	57	8	)	)	PUNCT
ajst-20185	57	9	were	be	AUX
ajst-20185	57	10	screened	screen	VERB
ajst-20185	57	11	to	to	PART
ajst-20185	57	12	identify	identify	VERB
ajst-20185	57	13	genes	gene	NOUN
ajst-20185	57	14	exhibiting	exhibit	VERB
ajst-20185	57	15	significant	significant	ADJ
ajst-20185	57	16	changes	change	NOUN
ajst-20185	57	17	in	in	ADP
ajst-20185	57	18	expression	expression	NOUN
ajst-20185	57	19	levels	level	NOUN
ajst-20185	57	20	during	during	ADP
ajst-20185	57	21	the	the	DET
ajst-20185	57	22	acid	acid	NOUN
ajst-20185	57	23	adaptation	adaptation	NOUN
ajst-20185	57	24	evolution	evolution	NOUN
ajst-20185	57	25	process	process	NOUN
ajst-20185	57	26	.	.	PUNCT
ajst-20185	58	1	subsequently	subsequently	ADV
ajst-20185	58	2	,	,	PUNCT
ajst-20185	58	3	functional	functional	ADJ
ajst-20185	58	4	and	and	CCONJ
ajst-20185	58	5	pathway	pathway	NOUN
ajst-20185	58	6	enrichment	enrichment	NOUN
ajst-20185	58	7	analyses	analysis	NOUN
ajst-20185	58	8	were	be	AUX
ajst-20185	58	9	performed	perform	VERB
ajst-20185	58	10	on	on	ADP
ajst-20185	58	11	the	the	DET
ajst-20185	58	12	degs	deg	NOUN
ajst-20185	58	13	to	to	PART
ajst-20185	58	14	elucidate	elucidate	VERB
ajst-20185	58	15	their	their	PRON
ajst-20185	58	16	roles	role	NOUN
ajst-20185	58	17	in	in	ADP
ajst-20185	58	18	biological	biological	ADJ
ajst-20185	58	19	processes	process	NOUN
ajst-20185	58	20	and	and	CCONJ
ajst-20185	58	21	molecular	molecular	ADJ
ajst-20185	58	22	functions	function	NOUN
ajst-20185	58	23	,	,	PUNCT
ajst-20185	58	24	as	as	ADV
ajst-20185	58	25	well	well	ADV
ajst-20185	58	26	as	as	ADP
ajst-20185	58	27	their	their	PRON
ajst-20185	58	28	interactions	interaction	NOUN
ajst-20185	58	29	and	and	CCONJ
ajst-20185	58	30	regulatory	regulatory	ADJ
ajst-20185	58	31	mechanisms	mechanism	NOUN
ajst-20185	58	32	within	within	ADP
ajst-20185	58	33	metabolic	metabolic	NOUN
ajst-20185	58	34	pathways	pathway	NOUN
ajst-20185	58	35	.	.	PUNCT
ajst-20185	59	1	3	3	X
ajst-20185	59	2	.	.	X
ajst-20185	59	3	results	result	NOUN
ajst-20185	59	4	and	and	CCONJ
ajst-20185	59	5	discussion	discussion	NOUN
ajst-20185	59	6	3.1	3.1	NUM
ajst-20185	59	7	.	.	PUNCT
ajst-20185	60	1	analysis	analysis	NOUN
ajst-20185	60	2	of	of	ADP
ajst-20185	60	3	acid	acid	ADJ
ajst-20185	60	4	adaptation	adaptation	NOUN
ajst-20185	60	5	evolution	evolution	NOUN
ajst-20185	60	6	through	through	ADP
ajst-20185	60	7	meticulously	meticulously	ADV
ajst-20185	60	8	planned	plan	VERB
ajst-20185	60	9	iterative	iterative	NOUN
ajst-20185	60	10	acid	acid	NOUN
ajst-20185	60	11	adaptation	adaptation	NOUN
ajst-20185	60	12	evolution	evolution	NOUN
ajst-20185	60	13	experiments	experiment	NOUN
ajst-20185	60	14	,	,	PUNCT
ajst-20185	60	15	we	we	PRON
ajst-20185	60	16	have	have	AUX
ajst-20185	60	17	effectively	effectively	ADV
ajst-20185	60	18	bolstered	bolster	VERB
ajst-20185	60	19	the	the	DET
ajst-20185	60	20	adaptability	adaptability	NOUN
ajst-20185	60	21	of	of	ADP
ajst-20185	60	22	bacillus	bacillus	NOUN
ajst-20185	60	23	subtilis	subtili	NOUN
ajst-20185	60	24	to	to	ADP
ajst-20185	60	25	low	low	ADJ
ajst-20185	60	26	-	-	PUNCT
ajst-20185	60	27	ph	ph	ADJ
ajst-20185	60	28	environments	environment	NOUN
ajst-20185	60	29	.	.	PUNCT
ajst-20185	61	1	the	the	DET
ajst-20185	61	2	comprehensive	comprehensive	ADJ
ajst-20185	61	3	results	result	NOUN
ajst-20185	61	4	of	of	ADP
ajst-20185	61	5	our	our	PRON
ajst-20185	61	6	evolutionary	evolutionary	ADJ
ajst-20185	61	7	study	study	NOUN
ajst-20185	61	8	are	be	AUX
ajst-20185	61	9	outlined	outline	VERB
ajst-20185	61	10	as	as	SCONJ
ajst-20185	61	11	follows	follow	VERB
ajst-20185	61	12	:	:	PUNCT
ajst-20185	61	13	during	during	ADP
ajst-20185	61	14	the	the	DET
ajst-20185	61	15	initial	initial	ADJ
ajst-20185	61	16	adaptation	adaptation	NOUN
ajst-20185	61	17	stage	stage	NOUN
ajst-20185	61	18	,	,	PUNCT
ajst-20185	61	19	we	we	PRON
ajst-20185	61	20	assessed	assess	VERB
ajst-20185	61	21	the	the	DET
ajst-20185	61	22	growth	growth	NOUN
ajst-20185	61	23	of	of	ADP
ajst-20185	61	24	all	all	DET
ajst-20185	61	25	nine	nine	NUM
ajst-20185	61	26	bottles	bottle	NOUN
ajst-20185	61	27	of	of	ADP
ajst-20185	61	28	bacterial	bacterial	ADJ
ajst-20185	61	29	solution	solution	NOUN
ajst-20185	61	30	by	by	ADP
ajst-20185	61	31	measuring	measure	VERB
ajst-20185	61	32	their	their	PRON
ajst-20185	61	33	optical	optical	ADJ
ajst-20185	61	34	density	density	NOUN
ajst-20185	61	35	at	at	ADP
ajst-20185	61	36	600	600	NUM
ajst-20185	61	37	nm	nm	PRON
ajst-20185	61	38	(	(	PUNCT
ajst-20185	61	39	od600	od600	NOUN
ajst-20185	61	40	)	)	PUNCT
ajst-20185	61	41	.	.	PUNCT
ajst-20185	62	1	the	the	DET
ajst-20185	62	2	od600	od600	ADJ
ajst-20185	62	3	values	value	NOUN
ajst-20185	62	4	of	of	ADP
ajst-20185	62	5	all	all	DET
ajst-20185	62	6	nine	nine	NUM
ajst-20185	62	7	bottles	bottle	NOUN
ajst-20185	62	8	were	be	AUX
ajst-20185	62	9	found	find	VERB
ajst-20185	62	10	to	to	PART
ajst-20185	62	11	be	be	AUX
ajst-20185	62	12	significantly	significantly	ADV
ajst-20185	62	13	higher	high	ADJ
ajst-20185	62	14	compared	compare	VERB
ajst-20185	62	15	to	to	ADP
ajst-20185	62	16	the	the	DET
ajst-20185	62	17	sterilized	sterilize	VERB
ajst-20185	62	18	m3	m3	PROPN
ajst-20185	62	19	g	g	PROPN
ajst-20185	62	20	medium	medium	NOUN
ajst-20185	62	21	control	control	NOUN
ajst-20185	62	22	group	group	NOUN
ajst-20185	62	23	,	,	PUNCT
ajst-20185	62	24	indicating	indicate	VERB
ajst-20185	62	25	robust	robust	ADJ
ajst-20185	62	26	growth	growth	NOUN
ajst-20185	62	27	.	.	PUNCT
ajst-20185	63	1	as	as	ADP
ajst-20185	63	2	a	a	DET
ajst-20185	63	3	result	result	NOUN
ajst-20185	63	4	,	,	PUNCT
ajst-20185	63	5	none	none	NOUN
ajst-20185	63	6	of	of	ADP
ajst-20185	63	7	the	the	DET
ajst-20185	63	8	bacterial	bacterial	ADJ
ajst-20185	63	9	solutions	solution	NOUN
ajst-20185	63	10	were	be	AUX
ajst-20185	63	11	eliminated	eliminate	VERB
ajst-20185	63	12	in	in	ADP
ajst-20185	63	13	the	the	DET
ajst-20185	63	14	first	first	ADJ
ajst-20185	63	15	round	round	NOUN
ajst-20185	63	16	of	of	ADP
ajst-20185	63	17	evolution	evolution	NOUN
ajst-20185	63	18	.	.	PUNCT
ajst-20185	64	1	in	in	ADP
ajst-20185	64	2	the	the	DET
ajst-20185	64	3	second	second	ADJ
ajst-20185	64	4	round	round	NOUN
ajst-20185	64	5	of	of	ADP
ajst-20185	64	6	evolution	evolution	NOUN
ajst-20185	64	7	,	,	PUNCT
ajst-20185	64	8	we	we	PRON
ajst-20185	64	9	implemented	implement	VERB
ajst-20185	64	10	a	a	DET
ajst-20185	64	11	more	more	ADV
ajst-20185	64	12	stringent	stringent	ADJ
ajst-20185	64	13	screening	screening	NOUN
ajst-20185	64	14	process	process	NOUN
ajst-20185	64	15	to	to	PART
ajst-20185	64	16	monitor	monitor	VERB
ajst-20185	64	17	the	the	DET
ajst-20185	64	18	growth	growth	NOUN
ajst-20185	64	19	of	of	ADP
ajst-20185	64	20	the	the	DET
ajst-20185	64	21	nine	nine	NUM
ajst-20185	64	22	bacterial	bacterial	ADJ
ajst-20185	64	23	solutions	solution	NOUN
ajst-20185	64	24	.	.	PUNCT
ajst-20185	65	1	the	the	DET
ajst-20185	65	2	results	result	NOUN
ajst-20185	65	3	revealed	reveal	VERB
ajst-20185	65	4	that	that	SCONJ
ajst-20185	65	5	bottles	bottle	NOUN
ajst-20185	65	6	1	1	NUM
ajst-20185	65	7	,	,	PUNCT
ajst-20185	65	8	2	2	NUM
ajst-20185	65	9	,	,	PUNCT
ajst-20185	65	10	4	4	NUM
ajst-20185	65	11	,	,	PUNCT
ajst-20185	65	12	5	5	NUM
ajst-20185	65	13	,	,	PUNCT
ajst-20185	65	14	6	6	NUM
ajst-20185	65	15	,	,	PUNCT
ajst-20185	65	16	and	and	CCONJ
ajst-20185	65	17	9	9	NUM
ajst-20185	65	18	exhibited	exhibit	VERB
ajst-20185	65	19	od600	od600	ADJ
ajst-20185	65	20	values	value	NOUN
ajst-20185	65	21	of	of	ADP
ajst-20185	65	22	4.12	4.12	NUM
ajst-20185	65	23	,	,	PUNCT
ajst-20185	65	24	4.19	4.19	NUM
ajst-20185	65	25	,	,	PUNCT
ajst-20185	65	26	4.07	4.07	NUM
ajst-20185	65	27	,	,	PUNCT
ajst-20185	65	28	4.23	4.23	NUM
ajst-20185	65	29	,	,	PUNCT
ajst-20185	65	30	4.01	4.01	NUM
ajst-20185	65	31	,	,	PUNCT
ajst-20185	65	32	and	and	CCONJ
ajst-20185	65	33	3.96	3.96	NUM
ajst-20185	65	34	respectively	respectively	ADV
ajst-20185	65	35	significantly	significantly	ADV
ajst-20185	65	36	higher	high	ADJ
ajst-20185	65	37	than	than	ADP
ajst-20185	65	38	those	those	PRON
ajst-20185	65	39	of	of	ADP
ajst-20185	65	40	the	the	DET
ajst-20185	65	41	remaining	remain	VERB
ajst-20185	65	42	bottles	bottle	NOUN
ajst-20185	65	43	.	.	PUNCT
ajst-20185	66	1	based	base	VERB
ajst-20185	66	2	on	on	ADP
ajst-20185	66	3	these	these	DET
ajst-20185	66	4	findings	finding	NOUN
ajst-20185	66	5	,	,	PUNCT
ajst-20185	66	6	we	we	PRON
ajst-20185	66	7	have	have	AUX
ajst-20185	66	8	selected	select	VERB
ajst-20185	66	9	these	these	DET
ajst-20185	66	10	six	six	NUM
ajst-20185	66	11	bottles	bottle	NOUN
ajst-20185	66	12	for	for	ADP
ajst-20185	66	13	further	further	ADJ
ajst-20185	66	14	experimentation	experimentation	NOUN
ajst-20185	66	15	in	in	ADP
ajst-20185	66	16	our	our	PRON
ajst-20185	66	17	study	study	NOUN
ajst-20185	66	18	.	.	PUNCT
ajst-20185	67	1	in	in	ADP
ajst-20185	67	2	the	the	DET
ajst-20185	67	3	third	third	ADJ
ajst-20185	67	4	round	round	NOUN
ajst-20185	67	5	of	of	ADP
ajst-20185	67	6	evolution	evolution	NOUN
ajst-20185	67	7	,	,	PUNCT
ajst-20185	67	8	these	these	DET
ajst-20185	67	9	six	six	NUM
ajst-20185	67	10	bottles	bottle	NOUN
ajst-20185	67	11	continued	continue	VERB
ajst-20185	67	12	to	to	PART
ajst-20185	67	13	exhibit	exhibit	VERB
ajst-20185	67	14	a	a	DET
ajst-20185	67	15	consistently	consistently	ADV
ajst-20185	67	16	high	high	ADJ
ajst-20185	67	17	od600	od600	ADJ
ajst-20185	67	18	growth	growth	NOUN
ajst-20185	67	19	trend	trend	NOUN
ajst-20185	67	20	,	,	PUNCT
ajst-20185	67	21	with	with	ADP
ajst-20185	67	22	no	no	DET
ajst-20185	67	23	statistically	statistically	ADV
ajst-20185	67	24	significant	significant	ADJ
ajst-20185	67	25	differences	difference	NOUN
ajst-20185	67	26	observed	observe	VERB
ajst-20185	67	27	among	among	ADP
ajst-20185	67	28	them	they	PRON
ajst-20185	67	29	.	.	PUNCT
ajst-20185	68	1	as	as	ADP
ajst-20185	68	2	a	a	DET
ajst-20185	68	3	result	result	NOUN
ajst-20185	68	4	,	,	PUNCT
ajst-20185	68	5	it	it	PRON
ajst-20185	68	6	was	be	AUX
ajst-20185	68	7	determined	determine	VERB
ajst-20185	68	8	that	that	SCONJ
ajst-20185	68	9	all	all	DET
ajst-20185	68	10	six	six	NUM
ajst-20185	68	11	bottles	bottle	NOUN
ajst-20185	68	12	would	would	AUX
ajst-20185	68	13	be	be	AUX
ajst-20185	68	14	retained	retain	VERB
ajst-20185	68	15	in	in	ADP
ajst-20185	68	16	the	the	DET
ajst-20185	68	17	ongoing	ongoing	ADJ
ajst-20185	68	18	evolution	evolution	NOUN
ajst-20185	68	19	experiment	experiment	NOUN
ajst-20185	68	20	in	in	ADP
ajst-20185	68	21	anticipation	anticipation	NOUN
ajst-20185	68	22	of	of	ADP
ajst-20185	68	23	further	further	ADJ
ajst-20185	68	24	enhancements	enhancement	NOUN
ajst-20185	68	25	in	in	ADP
ajst-20185	68	26	adaptability	adaptability	NOUN
ajst-20185	68	27	.	.	PUNCT
ajst-20185	69	1	during	during	ADP
ajst-20185	69	2	the	the	DET
ajst-20185	69	3	critical	critical	ADJ
ajst-20185	69	4	fourth	fourth	ADJ
ajst-20185	69	5	round	round	NOUN
ajst-20185	69	6	of	of	ADP
ajst-20185	69	7	evolution	evolution	NOUN
ajst-20185	69	8	,	,	PUNCT
ajst-20185	69	9	bottles	bottle	NOUN
ajst-20185	69	10	1	1	NUM
ajst-20185	69	11	,	,	PUNCT
ajst-20185	69	12	5	5	NUM
ajst-20185	69	13	,	,	PUNCT
ajst-20185	69	14	and	and	CCONJ
ajst-20185	69	15	6	6	NUM
ajst-20185	69	16	demonstrated	demonstrate	VERB
ajst-20185	69	17	more	more	ADJ
ajst-20185	69	18	pronounced	pronounced	ADJ
ajst-20185	69	19	growth	growth	NOUN
ajst-20185	69	20	advantages	advantage	NOUN
ajst-20185	69	21	.	.	PUNCT
ajst-20185	70	1	notably	notably	ADV
ajst-20185	70	2	,	,	PUNCT
ajst-20185	70	3	bottle	bottle	NOUN
ajst-20185	70	4	1	1	NUM
ajst-20185	70	5	exhibited	exhibit	VERB
ajst-20185	70	6	the	the	DET
ajst-20185	70	7	highest	high	ADJ
ajst-20185	70	8	od600	od600	ADJ
ajst-20185	70	9	value	value	NOUN
ajst-20185	70	10	of	of	ADP
ajst-20185	70	11	3.93	3.93	NUM
ajst-20185	70	12	,	,	PUNCT
ajst-20185	70	13	establishing	establish	VERB
ajst-20185	70	14	itself	itself	PRON
ajst-20185	70	15	as	as	ADP
ajst-20185	70	16	the	the	DET
ajst-20185	70	17	frontrunner	frontrunner	NOUN
ajst-20185	70	18	in	in	ADP
ajst-20185	70	19	this	this	DET
ajst-20185	70	20	evolutionary	evolutionary	ADJ
ajst-20185	70	21	stage	stage	NOUN
ajst-20185	70	22	.	.	PUNCT
ajst-20185	71	1	consequently	consequently	ADV
ajst-20185	71	2	,	,	PUNCT
ajst-20185	71	3	bottle	bottle	NOUN
ajst-20185	71	4	1	1	NUM
ajst-20185	71	5	was	be	AUX
ajst-20185	71	6	chosen	choose	VERB
ajst-20185	71	7	as	as	ADP
ajst-20185	71	8	the	the	DET
ajst-20185	71	9	representative	representative	NOUN
ajst-20185	71	10	for	for	ADP
ajst-20185	71	11	subsequent	subsequent	ADJ
ajst-20185	71	12	validation	validation	NOUN
ajst-20185	71	13	experiments	experiment	NOUN
ajst-20185	71	14	.	.	PUNCT
ajst-20185	72	1	to	to	PART
ajst-20185	72	2	validate	validate	VERB
ajst-20185	72	3	the	the	DET
ajst-20185	72	4	success	success	NOUN
ajst-20185	72	5	of	of	ADP
ajst-20185	72	6	acid	acid	ADJ
ajst-20185	72	7	adaptation	adaptation	NOUN
ajst-20185	72	8	evolution	evolution	NOUN
ajst-20185	72	9	,	,	PUNCT
ajst-20185	72	10	we	we	PRON
ajst-20185	72	11	conducted	conduct	VERB
ajst-20185	72	12	a	a	DET
ajst-20185	72	13	comparative	comparative	ADJ
ajst-20185	72	14	experiment	experiment	NOUN
ajst-20185	72	15	between	between	ADP
ajst-20185	72	16	the	the	DET
ajst-20185	72	17	evolved	evolved	ADJ
ajst-20185	72	18	strain	strain	NOUN
ajst-20185	72	19	from	from	ADP
ajst-20185	72	20	bottle	bottle	NOUN
ajst-20185	72	21	1	1	NUM
ajst-20185	72	22	and	and	CCONJ
ajst-20185	72	23	the	the	DET
ajst-20185	72	24	wild	wild	ADJ
ajst-20185	72	25	-	-	PUNCT
ajst-20185	72	26	type	type	NOUN
ajst-20185	72	27	strain	strain	NOUN
ajst-20185	72	28	.	.	PUNCT
ajst-20185	73	1	both	both	DET
ajst-20185	73	2	strains	strain	NOUN
ajst-20185	73	3	were	be	AUX
ajst-20185	73	4	inoculated	inoculate	VERB
ajst-20185	73	5	into	into	ADP
ajst-20185	73	6	a	a	DET
ajst-20185	73	7	sterilized	sterilize	VERB
ajst-20185	73	8	m3	m3	PROPN
ajst-20185	73	9	g	g	NOUN
ajst-20185	73	10	liquid	liquid	ADJ
ajst-20185	73	11	medium	medium	NOUN
ajst-20185	73	12	at	at	ADP
ajst-20185	73	13	ph	ph	PROPN
ajst-20185	73	14	4.5	4.5	NUM
ajst-20185	73	15	under	under	ADP
ajst-20185	73	16	identical	identical	ADJ
ajst-20185	73	17	conditions	condition	NOUN
ajst-20185	73	18	,	,	PUNCT
ajst-20185	73	19	and	and	CCONJ
ajst-20185	73	20	their	their	PRON
ajst-20185	73	21	growth	growth	NOUN
ajst-20185	73	22	rates	rate	NOUN
ajst-20185	73	23	were	be	AUX
ajst-20185	73	24	monitored	monitor	VERB
ajst-20185	73	25	.	.	PUNCT
ajst-20185	74	1	the	the	DET
ajst-20185	74	2	results	result	NOUN
ajst-20185	74	3	were	be	AUX
ajst-20185	74	4	remarkable	remarkable	ADJ
ajst-20185	74	5	:	:	PUNCT
ajst-20185	74	6	after	after	ADP
ajst-20185	74	7	a	a	DET
ajst-20185	74	8	12	12	NUM
ajst-20185	74	9	-	-	PUNCT
ajst-20185	74	10	hour	hour	NOUN
ajst-20185	74	11	incubation	incubation	NOUN
ajst-20185	74	12	period	period	NOUN
ajst-20185	74	13	,	,	PUNCT
ajst-20185	74	14	the	the	DET
ajst-20185	74	15	evolved	evolved	ADJ
ajst-20185	74	16	strain	strain	NOUN
ajst-20185	74	17	reached	reach	VERB
ajst-20185	74	18	an	an	DET
ajst-20185	74	19	od600	od600	ADJ
ajst-20185	74	20	value	value	NOUN
ajst-20185	74	21	of	of	ADP
ajst-20185	74	22	3.18	3.18	NUM
ajst-20185	74	23	,	,	PUNCT
ajst-20185	74	24	while	while	SCONJ
ajst-20185	74	25	the	the	DET
ajst-20185	74	26	wild	wild	ADJ
ajst-20185	74	27	-	-	PUNCT
ajst-20185	74	28	type	type	NOUN
ajst-20185	74	29	strain	strain	NOUN
ajst-20185	74	30	only	only	ADV
ajst-20185	74	31	achieved	achieve	VERB
ajst-20185	74	32	a	a	DET
ajst-20185	74	33	growth	growth	NOUN
ajst-20185	74	34	of	of	ADP
ajst-20185	74	35	1.32	1.32	NUM
ajst-20185	74	36	.	.	PUNCT
ajst-20185	75	1	this	this	DET
ajst-20185	75	2	significant	significant	ADJ
ajst-20185	75	3	disparity	disparity	NOUN
ajst-20185	75	4	unequivocally	unequivocally	ADV
ajst-20185	75	5	demonstrates	demonstrate	VERB
ajst-20185	75	6	the	the	DET
ajst-20185	75	7	exceptional	exceptional	ADJ
ajst-20185	75	8	efficacy	efficacy	NOUN
ajst-20185	75	9	of	of	ADP
ajst-20185	75	10	our	our	PRON
ajst-20185	75	11	acid	acid	NOUN
ajst-20185	75	12	adaptation	adaptation	NOUN
ajst-20185	75	13	evolution	evolution	NOUN
ajst-20185	75	14	strategy	strategy	NOUN
ajst-20185	75	15	.	.	PUNCT
ajst-20185	76	1	through	through	ADP
ajst-20185	76	2	a	a	DET
ajst-20185	76	3	series	series	NOUN
ajst-20185	76	4	of	of	ADP
ajst-20185	76	5	acid	acid	ADJ
ajst-20185	76	6	adaptation	adaptation	NOUN
ajst-20185	76	7	evolution	evolution	NOUN
ajst-20185	76	8	experiments	experiment	NOUN
ajst-20185	76	9	and	and	CCONJ
ajst-20185	76	10	validation	validation	NOUN
ajst-20185	76	11	processes	process	NOUN
ajst-20185	76	12	,	,	PUNCT
ajst-20185	76	13	we	we	PRON
ajst-20185	76	14	have	have	AUX
ajst-20185	76	15	successfully	successfully	ADV
ajst-20185	76	16	augmented	augment	VERB
ajst-20185	76	17	the	the	DET
ajst-20185	76	18	growth	growth	NOUN
ajst-20185	76	19	capacity	capacity	NOUN
ajst-20185	76	20	of	of	ADP
ajst-20185	76	21	bacillus	bacillus	NOUN
ajst-20185	76	22	subtilis	subtili	NOUN
ajst-20185	76	23	in	in	ADP
ajst-20185	76	24	low	low	ADJ
ajst-20185	76	25	-	-	PUNCT
ajst-20185	76	26	ph	ph	ADJ
ajst-20185	76	27	environments	environment	NOUN
ajst-20185	76	28	.	.	PUNCT
ajst-20185	77	1	this	this	DET
ajst-20185	77	2	accomplishment	accomplishment	NOUN
ajst-20185	77	3	provides	provide	VERB
ajst-20185	77	4	robust	robust	ADJ
ajst-20185	77	5	evidence	evidence	NOUN
ajst-20185	77	6	for	for	ADP
ajst-20185	77	7	a	a	DET
ajst-20185	77	8	deeper	deep	ADJ
ajst-20185	77	9	comprehension	comprehension	NOUN
ajst-20185	77	10	of	of	ADP
ajst-20185	77	11	microbial	microbial	ADJ
ajst-20185	77	12	adaptation	adaptation	NOUN
ajst-20185	77	13	mechanisms	mechanism	NOUN
ajst-20185	77	14	and	and	CCONJ
ajst-20185	77	15	unlocks	unlock	VERB
ajst-20185	77	16	new	new	ADJ
ajst-20185	77	17	potential	potential	NOUN
ajst-20185	77	18	for	for	ADP
ajst-20185	77	19	biotechnology	biotechnology	NOUN
ajst-20185	77	20	applications	application	NOUN
ajst-20185	77	21	in	in	ADP
ajst-20185	77	22	related	related	ADJ
ajst-20185	77	23	fields	field	NOUN
ajst-20185	77	24	.	.	PUNCT
ajst-20185	78	1	57	57	NUM
ajst-20185	78	2	figure	figure	NOUN
ajst-20185	78	3	3	3	NUM
ajst-20185	78	4	-	-	SYM
ajst-20185	78	5	1	1	NUM
ajst-20185	78	6	.	.	PUNCT
ajst-20185	78	7	growth	growth	NOUN
ajst-20185	78	8	verification	verification	NOUN
ajst-20185	78	9	experiment	experiment	NOUN
ajst-20185	78	10	of	of	ADP
ajst-20185	78	11	evolved	evolve	VERB
ajst-20185	78	12	strains	strain	NOUN
ajst-20185	78	13	3.2	3.2	NUM
ajst-20185	78	14	.	.	PUNCT
ajst-20185	79	1	differential	differential	ADJ
ajst-20185	79	2	expression	expression	NOUN
ajst-20185	79	3	of	of	ADP
ajst-20185	79	4	genes	gene	NOUN
ajst-20185	79	5	in	in	ADP
ajst-20185	79	6	the	the	DET
ajst-20185	79	7	transcriptome	transcriptome	NOUN
ajst-20185	79	8	and	and	CCONJ
ajst-20185	79	9	kegg	kegg	NOUN
ajst-20185	79	10	analysis	analysis	NOUN
ajst-20185	79	11	through	through	ADP
ajst-20185	79	12	comparison	comparison	NOUN
ajst-20185	79	13	of	of	ADP
ajst-20185	79	14	the	the	DET
ajst-20185	79	15	expressed	express	VERB
ajst-20185	79	16	genes	gene	NOUN
ajst-20185	79	17	in	in	ADP
ajst-20185	79	18	the	the	DET
ajst-20185	79	19	experimental	experimental	ADJ
ajst-20185	79	20	group	group	NOUN
ajst-20185	80	1	,	,	PUNCT
ajst-20185	80	2	we	we	PRON
ajst-20185	80	3	identified	identify	VERB
ajst-20185	80	4	672	672	NUM
ajst-20185	80	5	upregulated	upregulated	ADJ
ajst-20185	80	6	genes	gene	NOUN
ajst-20185	80	7	,	,	PUNCT
ajst-20185	80	8	including	include	VERB
ajst-20185	80	9	gsib	gsib	NOUN
ajst-20185	80	10	,	,	PUNCT
ajst-20185	80	11	glpk	glpk	NOUN
ajst-20185	80	12	,	,	PUNCT
ajst-20185	80	13	and	and	CCONJ
ajst-20185	80	14	ohrb	ohrb	PROPN
ajst-20185	80	15	.	.	PUNCT
ajst-20185	81	1	notably	notably	ADV
ajst-20185	81	2	,	,	PUNCT
ajst-20185	81	3	the	the	DET
ajst-20185	81	4	upregulation	upregulation	NOUN
ajst-20185	81	5	of	of	ADP
ajst-20185	81	6	the	the	DET
ajst-20185	81	7	glpk	glpk	NOUN
ajst-20185	81	8	gene	gene	NOUN
ajst-20185	81	9	,	,	PUNCT
ajst-20185	81	10	associated	associate	VERB
ajst-20185	81	11	with	with	ADP
ajst-20185	81	12	glycerol	glycerol	NOUN
ajst-20185	81	13	kinase	kinase	NOUN
ajst-20185	81	14	,	,	PUNCT
ajst-20185	81	15	may	may	AUX
ajst-20185	81	16	play	play	VERB
ajst-20185	81	17	a	a	DET
ajst-20185	81	18	role	role	NOUN
ajst-20185	81	19	in	in	ADP
ajst-20185	81	20	modulating	modulate	VERB
ajst-20185	81	21	cellular	cellular	ADJ
ajst-20185	81	22	membrane	membrane	NOUN
ajst-20185	81	23	lipid	lipid	NOUN
ajst-20185	81	24	synthesis	synthesis	NOUN
ajst-20185	81	25	or	or	CCONJ
ajst-20185	81	26	energy	energy	NOUN
ajst-20185	81	27	metabolism	metabolism	NOUN
ajst-20185	81	28	to	to	PART
ajst-20185	81	29	enhance	enhance	VERB
ajst-20185	81	30	cell	cell	NOUN
ajst-20185	81	31	survivability	survivability	NOUN
ajst-20185	81	32	under	under	ADP
ajst-20185	81	33	acidic	acidic	ADJ
ajst-20185	81	34	conditions	condition	NOUN
ajst-20185	81	35	.	.	PUNCT
ajst-20185	82	1	among	among	ADP
ajst-20185	82	2	the	the	DET
ajst-20185	82	3	656	656	NUM
ajst-20185	82	4	downregulated	downregulate	VERB
ajst-20185	82	5	genes	gene	NOUN
ajst-20185	82	6	,	,	PUNCT
ajst-20185	82	7	the	the	DET
ajst-20185	82	8	decrease	decrease	NOUN
ajst-20185	82	9	in	in	ADP
ajst-20185	82	10	expression	expression	NOUN
ajst-20185	82	11	of	of	ADP
ajst-20185	82	12	lcte	lcte	NOUN
ajst-20185	82	13	and	and	CCONJ
ajst-20185	82	14	lctp	lctp	NOUN
ajst-20185	82	15	,	,	PUNCT
ajst-20185	82	16	related	relate	VERB
ajst-20185	82	17	to	to	ADP
ajst-20185	82	18	lactic	lactic	ADJ
ajst-20185	82	19	acid	acid	NOUN
ajst-20185	82	20	metabolism	metabolism	NOUN
ajst-20185	82	21	,	,	PUNCT
ajst-20185	82	22	likely	likely	ADV
ajst-20185	82	23	signifies	signify	VERB
ajst-20185	82	24	a	a	DET
ajst-20185	82	25	reduction	reduction	NOUN
ajst-20185	82	26	in	in	ADP
ajst-20185	82	27	lactic	lactic	ADJ
ajst-20185	82	28	acid	acid	NOUN
ajst-20185	82	29	production	production	NOUN
ajst-20185	82	30	by	by	ADP
ajst-20185	82	31	the	the	DET
ajst-20185	82	32	cells	cell	NOUN
ajst-20185	82	33	under	under	ADP
ajst-20185	82	34	acidic	acidic	ADJ
ajst-20185	82	35	conditions	condition	NOUN
ajst-20185	82	36	as	as	ADP
ajst-20185	82	37	a	a	DET
ajst-20185	82	38	means	means	NOUN
ajst-20185	82	39	to	to	PART
ajst-20185	82	40	prevent	prevent	VERB
ajst-20185	82	41	further	further	ADJ
ajst-20185	82	42	acidification	acidification	NOUN
ajst-20185	82	43	.	.	PUNCT
ajst-20185	83	1	through	through	ADP
ajst-20185	83	2	a	a	DET
ajst-20185	83	3	comprehensive	comprehensive	ADJ
ajst-20185	83	4	kegg	kegg	NOUN
ajst-20185	83	5	enrichment	enrichment	NOUN
ajst-20185	83	6	analysis	analysis	NOUN
ajst-20185	83	7	,	,	PUNCT
ajst-20185	83	8	we	we	PRON
ajst-20185	83	9	observed	observe	VERB
ajst-20185	83	10	a	a	DET
ajst-20185	83	11	significant	significant	ADJ
ajst-20185	83	12	enrichment	enrichment	NOUN
ajst-20185	83	13	of	of	ADP
ajst-20185	83	14	differentially	differentially	ADV
ajst-20185	83	15	expressed	express	VERB
ajst-20185	83	16	genes	gene	NOUN
ajst-20185	83	17	(	(	PUNCT
ajst-20185	83	18	degs	deg	NOUN
ajst-20185	83	19	)	)	PUNCT
ajst-20185	83	20	in	in	ADP
ajst-20185	83	21	four	four	NUM
ajst-20185	83	22	primary	primary	ADJ
ajst-20185	83	23	metabolic	metabolic	NOUN
ajst-20185	83	24	pathways	pathway	NOUN
ajst-20185	83	25	:	:	PUNCT
ajst-20185	83	26	cellular	cellular	ADJ
ajst-20185	83	27	processes	process	NOUN
ajst-20185	83	28	,	,	PUNCT
ajst-20185	83	29	environmental	environmental	ADJ
ajst-20185	83	30	information	information	NOUN
ajst-20185	83	31	processing	processing	NOUN
ajst-20185	83	32	,	,	PUNCT
ajst-20185	83	33	human	human	ADJ
ajst-20185	83	34	disease	disease	NOUN
ajst-20185	83	35	,	,	PUNCT
ajst-20185	83	36	and	and	CCONJ
ajst-20185	83	37	metabolism	metabolism	NOUN
ajst-20185	83	38	(	(	PUNCT
ajst-20185	83	39	refer	refer	VERB
ajst-20185	83	40	to	to	PART
ajst-20185	83	41	figure	figure	VERB
ajst-20185	83	42	3	3	NUM
ajst-20185	83	43	-	-	SYM
ajst-20185	83	44	2	2	NUM
ajst-20185	83	45	for	for	ADP
ajst-20185	83	46	detailed	detailed	ADJ
ajst-20185	83	47	information	information	NOUN
ajst-20185	83	48	)	)	PUNCT
ajst-20185	83	49	.	.	PUNCT
ajst-20185	84	1	this	this	DET
ajst-20185	84	2	distribution	distribution	NOUN
ajst-20185	84	3	pattern	pattern	NOUN
ajst-20185	84	4	provides	provide	VERB
ajst-20185	84	5	insight	insight	NOUN
ajst-20185	84	6	into	into	ADP
ajst-20185	84	7	the	the	DET
ajst-20185	84	8	gene	gene	NOUN
ajst-20185	84	9	expression	expression	NOUN
ajst-20185	84	10	regulation	regulation	NOUN
ajst-20185	84	11	strategies	strategy	NOUN
ajst-20185	84	12	and	and	CCONJ
ajst-20185	84	13	metabolic	metabolic	NOUN
ajst-20185	84	14	remodeling	remodeling	NOUN
ajst-20185	84	15	mechanisms	mechanism	NOUN
ajst-20185	84	16	of	of	ADP
ajst-20185	84	17	bacillus	bacillus	NOUN
ajst-20185	84	18	subtilis	subtili	NOUN
ajst-20185	84	19	in	in	ADP
ajst-20185	84	20	response	response	NOUN
ajst-20185	84	21	to	to	ADP
ajst-20185	84	22	low	low	ADJ
ajst-20185	84	23	ph	ph	ADJ
ajst-20185	84	24	environments	environment	NOUN
ajst-20185	84	25	.	.	PUNCT
ajst-20185	85	1	initially	initially	ADV
ajst-20185	85	2	,	,	PUNCT
ajst-20185	85	3	it	it	PRON
ajst-20185	85	4	is	be	AUX
ajst-20185	85	5	noteworthy	noteworthy	ADJ
ajst-20185	85	6	that	that	SCONJ
ajst-20185	85	7	while	while	SCONJ
ajst-20185	85	8	degs	deg	NOUN
ajst-20185	85	9	are	be	AUX
ajst-20185	85	10	enriched	enrich	VERB
ajst-20185	85	11	in	in	ADP
ajst-20185	85	12	cellular	cellular	ADJ
ajst-20185	85	13	processes	process	NOUN
ajst-20185	85	14	,	,	PUNCT
ajst-20185	85	15	environmental	environmental	ADJ
ajst-20185	85	16	information	information	NOUN
ajst-20185	85	17	processing	processing	NOUN
ajst-20185	85	18	,	,	PUNCT
ajst-20185	85	19	and	and	CCONJ
ajst-20185	85	20	human	human	ADJ
ajst-20185	85	21	disease	disease	NOUN
ajst-20185	85	22	,	,	PUNCT
ajst-20185	85	23	the	the	DET
ajst-20185	85	24	number	number	NOUN
ajst-20185	85	25	of	of	ADP
ajst-20185	85	26	enriched	enriched	ADJ
ajst-20185	85	27	genes	gene	NOUN
ajst-20185	85	28	is	be	AUX
ajst-20185	85	29	relatively	relatively	ADV
ajst-20185	85	30	limited	limited	ADJ
ajst-20185	85	31	.	.	PUNCT
ajst-20185	86	1	this	this	PRON
ajst-20185	86	2	indicates	indicate	VERB
ajst-20185	86	3	that	that	SCONJ
ajst-20185	86	4	bacillus	bacillus	NOUN
ajst-20185	86	5	subtilis	subtili	NOUN
ajst-20185	86	6	's	's	PART
ajst-20185	86	7	adaptive	adaptive	ADJ
ajst-20185	86	8	evolution	evolution	NOUN
ajst-20185	86	9	under	under	ADP
ajst-20185	86	10	low	low	ADJ
ajst-20185	86	11	ph	ph	ADJ
ajst-20185	86	12	conditions	condition	NOUN
ajst-20185	86	13	does	do	AUX
ajst-20185	86	14	not	not	PART
ajst-20185	86	15	primarily	primarily	ADV
ajst-20185	86	16	depend	depend	VERB
ajst-20185	86	17	on	on	ADP
ajst-20185	86	18	the	the	DET
ajst-20185	86	19	regulation	regulation	NOUN
ajst-20185	86	20	of	of	ADP
ajst-20185	86	21	these	these	DET
ajst-20185	86	22	pathways	pathway	NOUN
ajst-20185	86	23	.	.	PUNCT
ajst-20185	87	1	however	however	ADV
ajst-20185	87	2	,	,	PUNCT
ajst-20185	87	3	specific	specific	ADJ
ajst-20185	87	4	gene	gene	NOUN
ajst-20185	87	5	alterations	alteration	NOUN
ajst-20185	87	6	within	within	ADP
ajst-20185	87	7	these	these	DET
ajst-20185	87	8	pathways	pathway	NOUN
ajst-20185	87	9	may	may	AUX
ajst-20185	87	10	still	still	ADV
ajst-20185	87	11	play	play	VERB
ajst-20185	87	12	a	a	DET
ajst-20185	87	13	pivotal	pivotal	ADJ
ajst-20185	87	14	role	role	NOUN
ajst-20185	87	15	in	in	ADP
ajst-20185	87	16	the	the	DET
ajst-20185	87	17	survival	survival	NOUN
ajst-20185	87	18	and	and	CCONJ
ajst-20185	87	19	adaptability	adaptability	NOUN
ajst-20185	87	20	of	of	ADP
ajst-20185	87	21	cells	cell	NOUN
ajst-20185	87	22	under	under	ADP
ajst-20185	87	23	low	low	ADJ
ajst-20185	87	24	ph	ph	ADJ
ajst-20185	87	25	conditions	condition	NOUN
ajst-20185	87	26	,	,	PUNCT
ajst-20185	87	27	necessitating	necessitate	VERB
ajst-20185	87	28	further	further	ADJ
ajst-20185	87	29	comprehensive	comprehensive	ADJ
ajst-20185	87	30	investigations	investigation	NOUN
ajst-20185	87	31	to	to	PART
ajst-20185	87	32	elucidate	elucidate	VERB
ajst-20185	87	33	their	their	PRON
ajst-20185	87	34	precise	precise	ADJ
ajst-20185	87	35	functions	function	NOUN
ajst-20185	87	36	.	.	PUNCT
ajst-20185	88	1	contrastingly	contrastingly	ADV
ajst-20185	88	2	,	,	PUNCT
ajst-20185	88	3	there	there	PRON
ajst-20185	88	4	is	be	VERB
ajst-20185	88	5	a	a	DET
ajst-20185	88	6	notable	notable	ADJ
ajst-20185	88	7	enrichment	enrichment	NOUN
ajst-20185	88	8	of	of	ADP
ajst-20185	88	9	genes	gene	NOUN
ajst-20185	88	10	in	in	ADP
ajst-20185	88	11	the	the	DET
ajst-20185	88	12	metabolism	metabolism	NOUN
ajst-20185	88	13	pathway	pathway	NOUN
ajst-20185	88	14	,	,	PUNCT
ajst-20185	88	15	particularly	particularly	ADV
ajst-20185	88	16	in	in	ADP
ajst-20185	88	17	amino	amino	NOUN
ajst-20185	88	18	acid	acid	NOUN
ajst-20185	88	19	metabolism	metabolism	NOUN
ajst-20185	88	20	and	and	CCONJ
ajst-20185	88	21	biosynthesis	biosynthesis	NOUN
ajst-20185	88	22	-	-	PUNCT
ajst-20185	88	23	related	relate	VERB
ajst-20185	88	24	pathways	pathway	NOUN
ajst-20185	88	25	.	.	PUNCT
ajst-20185	89	1	specifically	specifically	ADV
ajst-20185	89	2	,	,	PUNCT
ajst-20185	89	3	histidine	histidine	ADJ
ajst-20185	89	4	metabolism	metabolism	NOUN
ajst-20185	89	5	,	,	PUNCT
ajst-20185	89	6	arginine	arginine	NOUN
ajst-20185	89	7	biosynthesis	biosynthesis	NOUN
ajst-20185	89	8	,	,	PUNCT
ajst-20185	89	9	tryptophan	tryptophan	NOUN
ajst-20185	89	10	metabolism	metabolism	NOUN
ajst-20185	89	11	,	,	PUNCT
ajst-20185	89	12	and	and	CCONJ
ajst-20185	89	13	cyanoamino	cyanoamino	PROPN
ajst-20185	89	14	acid	acid	PROPN
ajst-20185	89	15	metabolism	metabolism	NOUN
ajst-20185	89	16	represent	represent	VERB
ajst-20185	89	17	a	a	DET
ajst-20185	89	18	substantial	substantial	ADJ
ajst-20185	89	19	proportion	proportion	NOUN
ajst-20185	89	20	of	of	ADP
ajst-20185	89	21	the	the	DET
ajst-20185	89	22	differentially	differentially	ADV
ajst-20185	89	23	expressed	express	VERB
ajst-20185	89	24	genes	gene	NOUN
ajst-20185	89	25	(	(	PUNCT
ajst-20185	89	26	degs	deg	NOUN
ajst-20185	89	27	)	)	PUNCT
ajst-20185	89	28	.	.	PUNCT
ajst-20185	90	1	this	this	DET
ajst-20185	90	2	discovery	discovery	NOUN
ajst-20185	90	3	strongly	strongly	ADV
ajst-20185	90	4	suggests	suggest	VERB
ajst-20185	90	5	that	that	SCONJ
ajst-20185	90	6	amino	amino	NOUN
ajst-20185	90	7	acid	acid	NOUN
ajst-20185	90	8	metabolism	metabolism	NOUN
ajst-20185	90	9	plays	play	VERB
ajst-20185	90	10	a	a	DET
ajst-20185	90	11	crucial	crucial	ADJ
ajst-20185	90	12	role	role	NOUN
ajst-20185	90	13	in	in	ADP
ajst-20185	90	14	bacillus	bacillus	NOUN
ajst-20185	90	15	subtilis	subtili	NOUN
ajst-20185	90	16	's	's	PART
ajst-20185	90	17	ability	ability	NOUN
ajst-20185	90	18	to	to	PART
ajst-20185	90	19	adapt	adapt	VERB
ajst-20185	90	20	to	to	ADP
ajst-20185	90	21	low	low	ADJ
ajst-20185	90	22	ph	ph	ADJ
ajst-20185	90	23	conditions	condition	NOUN
ajst-20185	90	24	.	.	PUNCT
ajst-20185	91	1	in	in	ADP
ajst-20185	91	2	the	the	DET
ajst-20185	91	3	presence	presence	NOUN
ajst-20185	91	4	of	of	ADP
ajst-20185	91	5	low	low	ADJ
ajst-20185	91	6	ph	ph	ADJ
ajst-20185	91	7	conditions	condition	NOUN
ajst-20185	91	8	,	,	PUNCT
ajst-20185	91	9	microbial	microbial	ADJ
ajst-20185	91	10	cells	cell	NOUN
ajst-20185	91	11	are	be	AUX
ajst-20185	91	12	subjected	subject	VERB
ajst-20185	91	13	to	to	ADP
ajst-20185	91	14	a	a	DET
ajst-20185	91	15	multitude	multitude	NOUN
ajst-20185	91	16	of	of	ADP
ajst-20185	91	17	stresses	stress	NOUN
ajst-20185	91	18	,	,	PUNCT
ajst-20185	91	19	including	include	VERB
ajst-20185	91	20	compromised	compromise	VERB
ajst-20185	91	21	membrane	membrane	NOUN
ajst-20185	91	22	stability	stability	NOUN
ajst-20185	91	23	,	,	PUNCT
ajst-20185	91	24	altered	alter	VERB
ajst-20185	91	25	proton	proton	NOUN
ajst-20185	91	26	motive	motive	NOUN
ajst-20185	91	27	force	force	NOUN
ajst-20185	91	28	,	,	PUNCT
ajst-20185	91	29	and	and	CCONJ
ajst-20185	91	30	intracellular	intracellular	ADJ
ajst-20185	91	31	acid	acid	ADJ
ajst-20185	91	32	-	-	PUNCT
ajst-20185	91	33	base	base	NOUN
ajst-20185	91	34	imbalances	imbalance	NOUN
ajst-20185	91	35	.	.	PUNCT
ajst-20185	92	1	modulating	modulate	VERB
ajst-20185	92	2	specific	specific	ADJ
ajst-20185	92	3	metabolic	metabolic	NOUN
ajst-20185	92	4	pathways	pathway	NOUN
ajst-20185	92	5	,	,	PUNCT
ajst-20185	92	6	particularly	particularly	ADV
ajst-20185	92	7	those	those	PRON
ajst-20185	92	8	related	relate	VERB
ajst-20185	92	9	to	to	ADP
ajst-20185	92	10	amino	amino	NOUN
ajst-20185	92	11	acid	acid	NOUN
ajst-20185	92	12	metabolism	metabolism	NOUN
ajst-20185	92	13	,	,	PUNCT
ajst-20185	92	14	may	may	AUX
ajst-20185	92	15	represent	represent	VERB
ajst-20185	92	16	a	a	DET
ajst-20185	92	17	pivotal	pivotal	ADJ
ajst-20185	92	18	strategy	strategy	NOUN
ajst-20185	92	19	for	for	SCONJ
ajst-20185	92	20	cells	cell	NOUN
ajst-20185	92	21	to	to	PART
ajst-20185	92	22	adapt	adapt	VERB
ajst-20185	92	23	to	to	ADP
ajst-20185	92	24	these	these	DET
ajst-20185	92	25	challenges	challenge	NOUN
ajst-20185	92	26	.	.	PUNCT
ajst-20185	93	1	amino	amino	ADJ
ajst-20185	93	2	acids	acid	NOUN
ajst-20185	93	3	play	play	VERB
ajst-20185	93	4	a	a	DET
ajst-20185	93	5	crucial	crucial	ADJ
ajst-20185	93	6	role	role	NOUN
ajst-20185	93	7	not	not	PART
ajst-20185	93	8	only	only	ADV
ajst-20185	93	9	in	in	ADP
ajst-20185	93	10	protein	protein	NOUN
ajst-20185	93	11	synthesis	synthesis	NOUN
ajst-20185	93	12	but	but	CCONJ
ajst-20185	93	13	also	also	ADV
ajst-20185	93	14	in	in	ADP
ajst-20185	93	15	various	various	ADJ
ajst-20185	93	16	essential	essential	ADJ
ajst-20185	93	17	cellular	cellular	ADJ
ajst-20185	93	18	processes	process	NOUN
ajst-20185	93	19	such	such	ADJ
ajst-20185	93	20	as	as	ADP
ajst-20185	93	21	energy	energy	NOUN
ajst-20185	93	22	metabolism	metabolism	NOUN
ajst-20185	93	23	,	,	PUNCT
ajst-20185	93	24	signal	signal	ADJ
ajst-20185	93	25	transduction	transduction	NOUN
ajst-20185	93	26	,	,	PUNCT
ajst-20185	93	27	and	and	CCONJ
ajst-20185	93	28	cell	cell	NOUN
ajst-20185	93	29	wall	wall	NOUN
ajst-20185	93	30	synthesis	synthesis	NOUN
ajst-20185	93	31	.	.	PUNCT
ajst-20185	94	1	augmenting	augment	VERB
ajst-20185	94	2	the	the	DET
ajst-20185	94	3	demand	demand	NOUN
ajst-20185	94	4	for	for	ADP
ajst-20185	94	5	and	and	CCONJ
ajst-20185	94	6	synthesis	synthesis	NOUN
ajst-20185	94	7	of	of	ADP
ajst-20185	94	8	amino	amino	ADJ
ajst-20185	94	9	acids	acid	NOUN
ajst-20185	94	10	could	could	AUX
ajst-20185	94	11	potentially	potentially	ADV
ajst-20185	94	12	aid	aid	VERB
ajst-20185	94	13	cells	cell	NOUN
ajst-20185	94	14	in	in	ADP
ajst-20185	94	15	preserving	preserve	VERB
ajst-20185	94	16	membrane	membrane	NOUN
ajst-20185	94	17	integrity	integrity	NOUN
ajst-20185	94	18	and	and	CCONJ
ajst-20185	94	19	functionality	functionality	NOUN
ajst-20185	94	20	,	,	PUNCT
ajst-20185	94	21	regulating	regulate	VERB
ajst-20185	94	22	intracellular	intracellular	ADJ
ajst-20185	94	23	ph	ph	ADJ
ajst-20185	94	24	levels	level	NOUN
ajst-20185	94	25	,	,	PUNCT
ajst-20185	94	26	and	and	CCONJ
ajst-20185	94	27	ensuring	ensure	VERB
ajst-20185	94	28	the	the	DET
ajst-20185	94	29	smooth	smooth	ADJ
ajst-20185	94	30	operation	operation	NOUN
ajst-20185	94	31	of	of	ADP
ajst-20185	94	32	key	key	ADJ
ajst-20185	94	33	biosynthetic	biosynthetic	ADJ
ajst-20185	94	34	pathways	pathway	NOUN
ajst-20185	94	35	.	.	PUNCT
ajst-20185	95	1	in	in	ADP
ajst-20185	95	2	conclusion	conclusion	NOUN
ajst-20185	95	3	,	,	PUNCT
ajst-20185	95	4	the	the	DET
ajst-20185	95	5	results	result	NOUN
ajst-20185	95	6	of	of	ADP
ajst-20185	95	7	the	the	DET
ajst-20185	95	8	kegg	kegg	NOUN
ajst-20185	95	9	enrichment	enrichment	NOUN
ajst-20185	95	10	analysis	analysis	NOUN
ajst-20185	95	11	reveal	reveal	VERB
ajst-20185	95	12	a	a	DET
ajst-20185	95	13	significant	significant	ADJ
ajst-20185	95	14	adaptive	adaptive	ADJ
ajst-20185	95	15	strategy	strategy	NOUN
ajst-20185	95	16	employed	employ	VERB
ajst-20185	95	17	by	by	ADP
ajst-20185	95	18	bacillus	bacillus	NOUN
ajst-20185	95	19	subtilis	subtili	NOUN
ajst-20185	95	20	in	in	ADP
ajst-20185	95	21	response	response	NOUN
ajst-20185	95	22	to	to	ADP
ajst-20185	95	23	low	low	ADJ
ajst-20185	95	24	ph	ph	ADJ
ajst-20185	95	25	conditions	condition	NOUN
ajst-20185	95	26	:	:	PUNCT
ajst-20185	95	27	maintaining	maintain	VERB
ajst-20185	95	28	cell	cell	NOUN
ajst-20185	95	29	survival	survival	NOUN
ajst-20185	95	30	and	and	CCONJ
ajst-20185	95	31	normal	normal	ADJ
ajst-20185	95	32	physiological	physiological	ADJ
ajst-20185	95	33	functions	function	NOUN
ajst-20185	95	34	through	through	ADP
ajst-20185	95	35	metabolic	metabolic	NOUN
ajst-20185	95	36	network	network	NOUN
ajst-20185	95	37	remodeling	remodeling	NOUN
ajst-20185	95	38	,	,	PUNCT
ajst-20185	95	39	particularly	particularly	ADV
ajst-20185	95	40	by	by	ADP
ajst-20185	95	41	enhancing	enhance	VERB
ajst-20185	95	42	amino	amino	NOUN
ajst-20185	95	43	acid	acid	NOUN
ajst-20185	95	44	metabolism	metabolism	NOUN
ajst-20185	95	45	and	and	CCONJ
ajst-20185	95	46	biosynthetic	biosynthetic	ADJ
ajst-20185	95	47	pathways	pathway	NOUN
ajst-20185	95	48	.	.	PUNCT
ajst-20185	96	1	these	these	DET
ajst-20185	96	2	findings	finding	NOUN
ajst-20185	96	3	not	not	PART
ajst-20185	96	4	only	only	ADV
ajst-20185	96	5	enhance	enhance	VERB
ajst-20185	96	6	our	our	PRON
ajst-20185	96	7	comprehension	comprehension	NOUN
ajst-20185	96	8	of	of	ADP
ajst-20185	96	9	microbial	microbial	ADJ
ajst-20185	96	10	adaptation	adaptation	NOUN
ajst-20185	96	11	mechanisms	mechanism	NOUN
ajst-20185	96	12	but	but	CCONJ
ajst-20185	96	13	also	also	ADV
ajst-20185	96	14	offer	offer	VERB
ajst-20185	96	15	valuable	valuable	ADJ
ajst-20185	96	16	insights	insight	NOUN
ajst-20185	96	17	for	for	ADP
ajst-20185	96	18	the	the	DET
ajst-20185	96	19	development	development	NOUN
ajst-20185	96	20	of	of	ADP
ajst-20185	96	21	industrial	industrial	ADJ
ajst-20185	96	22	microbial	microbial	ADJ
ajst-20185	96	23	strains	strain	NOUN
ajst-20185	96	24	with	with	ADP
ajst-20185	96	25	enhanced	enhanced	ADJ
ajst-20185	96	26	environmental	environmental	ADJ
ajst-20185	96	27	adaptability	adaptability	NOUN
ajst-20185	96	28	.	.	PUNCT
ajst-20185	97	1	0	0	NUM
ajst-20185	97	2	2	2	NUM
ajst-20185	97	3	4	4	NUM
ajst-20185	97	4	6	6	NUM
ajst-20185	97	5	8	8	NUM
ajst-20185	97	6	10	10	NUM
ajst-20185	97	7	12	12	NUM
ajst-20185	97	8	0.0	0.0	NUM
ajst-20185	97	9	0.5	0.5	NUM
ajst-20185	97	10	1.0	1.0	NUM
ajst-20185	97	11	1.5	1.5	NUM
ajst-20185	97	12	2.0	2.0	NUM
ajst-20185	97	13	2.5	2.5	NUM
ajst-20185	97	14	3.0	3.0	NUM
ajst-20185	97	15	3.5	3.5	NUM
ajst-20185	97	16	4.0	4.0	NUM
ajst-20185	97	17	time（h	time（h	PROPN
ajst-20185	97	18	）	）	PUNCT
ajst-20185	98	1	op	op	NOUN
ajst-20185	98	2	ti	ti	NOUN
ajst-20185	98	3	ca	ca	NOUN
ajst-20185	98	4	l	l	NOUN
ajst-20185	98	5	d	d	X
ajst-20185	98	6	en	en	X
ajst-20185	98	7	si	si	X
ajst-20185	98	8	ty	ty	X
ajst-20185	98	9	（	（	PROPN
ajst-20185	98	10	60	60	NUM
ajst-20185	98	11	0n	0n	NUM
ajst-20185	98	12	m	m	VERB
ajst-20185	98	13	）	）	PUNCT
ajst-20185	98	14	wild	wild	ADJ
ajst-20185	98	15	-	-	PUNCT
ajst-20185	98	16	type	type	NOUN
ajst-20185	98	17	strain	strain	NOUN
ajst-20185	98	18	evolved	evolve	VERB
ajst-20185	98	19	strain	strain	NOUN
ajst-20185	98	20	58	58	NUM
ajst-20185	98	21	figure	figure	NOUN
ajst-20185	98	22	3	3	NUM
ajst-20185	98	23	-	-	SYM
ajst-20185	98	24	2	2	NUM
ajst-20185	98	25	.	.	PUNCT
ajst-20185	98	26	kegg	kegg	NOUN
ajst-20185	98	27	pathway	pathway	NOUN
ajst-20185	98	28	enrichment	enrichment	NOUN
ajst-20185	98	29	results	result	NOUN
ajst-20185	98	30	histogram	histogram	VERB
ajst-20185	98	31	3.3	3.3	NUM
ajst-20185	98	32	.	.	PUNCT
ajst-20185	99	1	go	go	VERB
ajst-20185	99	2	enrichment	enrichment	NOUN
ajst-20185	99	3	analysis	analysis	NOUN
ajst-20185	99	4	of	of	ADP
ajst-20185	99	5	the	the	DET
ajst-20185	99	6	transcriptome	transcriptome	NOUN
ajst-20185	99	7	in	in	ADP
ajst-20185	99	8	order	order	NOUN
ajst-20185	99	9	to	to	PART
ajst-20185	99	10	further	far	ADV
ajst-20185	99	11	elucidate	elucidate	VERB
ajst-20185	99	12	the	the	DET
ajst-20185	99	13	functional	functional	ADJ
ajst-20185	99	14	roles	role	NOUN
ajst-20185	99	15	of	of	ADP
ajst-20185	99	16	differentially	differentially	ADV
ajst-20185	99	17	expressed	express	VERB
ajst-20185	99	18	genes	gene	NOUN
ajst-20185	99	19	during	during	ADP
ajst-20185	99	20	the	the	DET
ajst-20185	99	21	adaptive	adaptive	ADJ
ajst-20185	99	22	evolution	evolution	NOUN
ajst-20185	99	23	of	of	ADP
ajst-20185	99	24	bacillus	bacillus	NOUN
ajst-20185	99	25	subtilis	subtili	NOUN
ajst-20185	99	26	168	168	NUM
ajst-20185	99	27	under	under	ADP
ajst-20185	99	28	low	low	ADJ
ajst-20185	99	29	ph	ph	ADJ
ajst-20185	99	30	conditions	condition	NOUN
ajst-20185	99	31	,	,	PUNCT
ajst-20185	99	32	a	a	DET
ajst-20185	99	33	gene	gene	NOUN
ajst-20185	99	34	ontology	ontology	NOUN
ajst-20185	99	35	(	(	PUNCT
ajst-20185	99	36	go	go	VERB
ajst-20185	99	37	)	)	PUNCT
ajst-20185	99	38	enrichment	enrichment	NOUN
ajst-20185	99	39	analysis	analysis	NOUN
ajst-20185	99	40	of	of	ADP
ajst-20185	99	41	the	the	DET
ajst-20185	99	42	transcriptome	transcriptome	NOUN
ajst-20185	99	43	was	be	AUX
ajst-20185	99	44	conducted	conduct	VERB
ajst-20185	99	45	.	.	PUNCT
ajst-20185	100	1	this	this	DET
ajst-20185	100	2	analytical	analytical	ADJ
ajst-20185	100	3	approach	approach	NOUN
ajst-20185	100	4	reveals	reveal	VERB
ajst-20185	100	5	significantly	significantly	ADV
ajst-20185	100	6	regulated	regulate	VERB
ajst-20185	100	7	biological	biological	ADJ
ajst-20185	100	8	functions	function	NOUN
ajst-20185	100	9	under	under	ADP
ajst-20185	100	10	specific	specific	ADJ
ajst-20185	100	11	conditions	condition	NOUN
ajst-20185	100	12	by	by	ADP
ajst-20185	100	13	quantifying	quantify	VERB
ajst-20185	100	14	the	the	DET
ajst-20185	100	15	number	number	NOUN
ajst-20185	100	16	of	of	ADP
ajst-20185	100	17	genes	gene	NOUN
ajst-20185	100	18	associated	associate	VERB
ajst-20185	100	19	with	with	ADP
ajst-20185	100	20	each	each	DET
ajst-20185	100	21	go	go	ADJ
ajst-20185	100	22	term	term	NOUN
ajst-20185	100	23	(	(	PUNCT
ajst-20185	100	24	representing	represent	VERB
ajst-20185	100	25	specific	specific	ADJ
ajst-20185	100	26	biological	biological	ADJ
ajst-20185	100	27	functions	function	NOUN
ajst-20185	100	28	,	,	PUNCT
ajst-20185	100	29	processes	process	NOUN
ajst-20185	100	30	,	,	PUNCT
ajst-20185	100	31	or	or	CCONJ
ajst-20185	100	32	cellular	cellular	ADJ
ajst-20185	100	33	components	component	NOUN
ajst-20185	100	34	)	)	PUNCT
ajst-20185	100	35	and	and	CCONJ
ajst-20185	100	36	calculating	calculate	VERB
ajst-20185	100	37	enrichment	enrichment	NOUN
ajst-20185	100	38	significance	significance	NOUN
ajst-20185	100	39	using	use	VERB
ajst-20185	100	40	a	a	DET
ajst-20185	100	41	hypergeometric	hypergeometric	ADJ
ajst-20185	100	42	distribution	distribution	NOUN
ajst-20185	100	43	.	.	PUNCT
ajst-20185	101	1	after	after	ADP
ajst-20185	101	2	categorizing	categorize	VERB
ajst-20185	101	3	the	the	DET
ajst-20185	101	4	results	result	NOUN
ajst-20185	101	5	of	of	ADP
ajst-20185	101	6	go	go	VERB
ajst-20185	101	7	enrichment	enrichment	NOUN
ajst-20185	101	8	analysis	analysis	NOUN
ajst-20185	101	9	into	into	ADP
ajst-20185	101	10	molecular	molecular	ADJ
ajst-20185	101	11	function	function	NOUN
ajst-20185	101	12	(	(	PUNCT
ajst-20185	101	13	mf	mf	X
ajst-20185	101	14	)	)	PUNCT
ajst-20185	101	15	,	,	PUNCT
ajst-20185	101	16	biological	biological	ADJ
ajst-20185	101	17	process	process	NOUN
ajst-20185	101	18	(	(	PUNCT
ajst-20185	101	19	bp	bp	PROPN
ajst-20185	101	20	)	)	PUNCT
ajst-20185	101	21	,	,	PUNCT
ajst-20185	101	22	and	and	CCONJ
ajst-20185	101	23	cellular	cellular	ADJ
ajst-20185	101	24	component	component	NOUN
ajst-20185	101	25	(	(	PUNCT
ajst-20185	101	26	cc	cc	NOUN
ajst-20185	101	27	)	)	PUNCT
ajst-20185	101	28	,	,	PUNCT
ajst-20185	101	29	we	we	PRON
ajst-20185	101	30	have	have	AUX
ajst-20185	101	31	identified	identify	VERB
ajst-20185	101	32	and	and	CCONJ
ajst-20185	101	33	selected	select	VERB
ajst-20185	101	34	the	the	DET
ajst-20185	101	35	top	top	ADJ
ajst-20185	101	36	10	10	NUM
ajst-20185	101	37	most	most	ADV
ajst-20185	101	38	significantly	significantly	ADV
ajst-20185	101	39	enriched	enrich	VERB
ajst-20185	101	40	go	go	VERB
ajst-20185	101	41	terms	term	NOUN
ajst-20185	101	42	from	from	ADP
ajst-20185	101	43	each	each	DET
ajst-20185	101	44	category	category	NOUN
ajst-20185	101	45	for	for	ADP
ajst-20185	101	46	detailed	detailed	ADJ
ajst-20185	101	47	presentation	presentation	NOUN
ajst-20185	101	48	(	(	PUNCT
ajst-20185	101	49	figure	figure	NOUN
ajst-20185	101	50	3	3	NUM
ajst-20185	101	51	-	-	SYM
ajst-20185	101	52	3	3	NUM
ajst-20185	101	53	)	)	PUNCT
ajst-20185	101	54	.	.	PUNCT
ajst-20185	102	1	these	these	DET
ajst-20185	102	2	findings	finding	NOUN
ajst-20185	102	3	reveal	reveal	VERB
ajst-20185	102	4	the	the	DET
ajst-20185	102	5	primary	primary	ADJ
ajst-20185	102	6	biological	biological	ADJ
ajst-20185	102	7	functions	function	NOUN
ajst-20185	102	8	associated	associate	VERB
ajst-20185	102	9	with	with	ADP
ajst-20185	102	10	the	the	DET
ajst-20185	102	11	differentially	differentially	ADV
ajst-20185	102	12	expressed	express	VERB
ajst-20185	102	13	genes	gene	NOUN
ajst-20185	102	14	.	.	PUNCT
ajst-20185	103	1	within	within	ADP
ajst-20185	103	2	the	the	DET
ajst-20185	103	3	cellular	cellular	ADJ
ajst-20185	103	4	component	component	NOUN
ajst-20185	103	5	(	(	PUNCT
ajst-20185	103	6	cc	cc	NOUN
ajst-20185	103	7	)	)	PUNCT
ajst-20185	103	8	category	category	NOUN
ajst-20185	103	9	,	,	PUNCT
ajst-20185	103	10	significantly	significantly	ADV
ajst-20185	103	11	enriched	enrich	VERB
ajst-20185	104	1	go	go	NOUN
ajst-20185	104	2	terms	term	NOUN
ajst-20185	104	3	are	be	AUX
ajst-20185	104	4	predominantly	predominantly	ADV
ajst-20185	104	5	associated	associate	VERB
ajst-20185	104	6	with	with	ADP
ajst-20185	104	7	the	the	DET
ajst-20185	104	8	cell	cell	NOUN
ajst-20185	104	9	membrane	membrane	NOUN
ajst-20185	104	10	and	and	CCONJ
ajst-20185	104	11	its	its	PRON
ajst-20185	104	12	constituents	constituent	NOUN
ajst-20185	104	13	,	,	PUNCT
ajst-20185	104	14	such	such	ADJ
ajst-20185	104	15	as	as	ADP
ajst-20185	104	16	"	"	PUNCT
ajst-20185	104	17	membrane	membrane	NOUN
ajst-20185	104	18	"	"	PUNCT
ajst-20185	104	19	(	(	PUNCT
ajst-20185	104	20	go:0016020	go:0016020	PROPN
ajst-20185	104	21	)	)	PUNCT
ajst-20185	104	22	and	and	CCONJ
ajst-20185	104	23	"	"	PUNCT
ajst-20185	104	24	plasma	plasma	NOUN
ajst-20185	104	25	membrane	membrane	NOUN
ajst-20185	104	26	"	"	PUNCT
ajst-20185	104	27	(	(	PUNCT
ajst-20185	104	28	go:0005886	go:0005886	NOUN
ajst-20185	104	29	)	)	PUNCT
ajst-20185	104	30	.	.	PUNCT
ajst-20185	105	1	this	this	PRON
ajst-20185	105	2	suggests	suggest	VERB
ajst-20185	105	3	that	that	SCONJ
ajst-20185	105	4	under	under	ADP
ajst-20185	105	5	acidic	acidic	ADJ
ajst-20185	105	6	conditions	condition	NOUN
ajst-20185	105	7	,	,	PUNCT
ajst-20185	105	8	bacillus	bacillus	NOUN
ajst-20185	105	9	subtilis	subtili	NOUN
ajst-20185	105	10	enhances	enhance	VERB
ajst-20185	105	11	the	the	DET
ajst-20185	105	12	stability	stability	NOUN
ajst-20185	105	13	and	and	CCONJ
ajst-20185	105	14	material	material	NOUN
ajst-20185	105	15	transport	transport	NOUN
ajst-20185	105	16	capabilities	capability	NOUN
ajst-20185	105	17	of	of	ADP
ajst-20185	105	18	the	the	DET
ajst-20185	105	19	cell	cell	NOUN
ajst-20185	105	20	membrane	membrane	NOUN
ajst-20185	105	21	by	by	ADP
ajst-20185	105	22	significantly	significantly	ADV
ajst-20185	105	23	upregulating	upregulate	VERB
ajst-20185	105	24	the	the	DET
ajst-20185	105	25	expression	expression	NOUN
ajst-20185	105	26	of	of	ADP
ajst-20185	105	27	genes	gene	NOUN
ajst-20185	105	28	related	relate	VERB
ajst-20185	105	29	to	to	ADP
ajst-20185	105	30	membrane	membrane	NOUN
ajst-20185	105	31	structure	structure	NOUN
ajst-20185	105	32	and	and	CCONJ
ajst-20185	105	33	function	function	NOUN
ajst-20185	105	34	,	,	PUNCT
ajst-20185	105	35	thereby	thereby	ADV
ajst-20185	105	36	adapting	adapt	VERB
ajst-20185	105	37	to	to	ADP
ajst-20185	105	38	the	the	DET
ajst-20185	105	39	stress	stress	NOUN
ajst-20185	105	40	of	of	ADP
ajst-20185	105	41	the	the	DET
ajst-20185	105	42	low	low	ADJ
ajst-20185	105	43	ph	ph	ADJ
ajst-20185	105	44	environment	environment	NOUN
ajst-20185	105	45	.	.	PUNCT
ajst-20185	106	1	in	in	ADP
ajst-20185	106	2	the	the	DET
ajst-20185	106	3	molecular	molecular	ADJ
ajst-20185	106	4	function	function	NOUN
ajst-20185	106	5	(	(	PUNCT
ajst-20185	106	6	mf	mf	NOUN
ajst-20185	106	7	)	)	PUNCT
ajst-20185	106	8	category	category	NOUN
ajst-20185	106	9	,	,	PUNCT
ajst-20185	106	10	enriched	enrich	VERB
ajst-20185	106	11	go	go	VERB
ajst-20185	106	12	terms	term	NOUN
ajst-20185	106	13	primarily	primarily	ADV
ajst-20185	106	14	focus	focus	VERB
ajst-20185	106	15	on	on	ADP
ajst-20185	106	16	transporter	transporter	NOUN
ajst-20185	106	17	activity	activity	NOUN
ajst-20185	106	18	,	,	PUNCT
ajst-20185	106	19	such	such	ADJ
ajst-20185	106	20	as	as	ADP
ajst-20185	106	21	"	"	PUNCT
ajst-20185	106	22	transmembrane	transmembrane	ADJ
ajst-20185	106	23	transporter	transporter	NOUN
ajst-20185	106	24	activity	activity	NOUN
ajst-20185	106	25	"	"	PUNCT
ajst-20185	106	26	(	(	PUNCT
ajst-20185	106	27	go:0022857	go:0022857	NOUN
ajst-20185	106	28	)	)	PUNCT
ajst-20185	106	29	and	and	CCONJ
ajst-20185	106	30	"	"	PUNCT
ajst-20185	106	31	transporter	transporter	NOUN
ajst-20185	106	32	activity	activity	NOUN
ajst-20185	106	33	"	"	PUNCT
ajst-20185	106	34	(	(	PUNCT
ajst-20185	106	35	go:0005215	go:0005215	NOUN
ajst-20185	106	36	)	)	PUNCT
ajst-20185	106	37	.	.	PUNCT
ajst-20185	107	1	these	these	DET
ajst-20185	107	2	findings	finding	NOUN
ajst-20185	107	3	suggest	suggest	VERB
ajst-20185	107	4	that	that	SCONJ
ajst-20185	107	5	under	under	ADP
ajst-20185	107	6	acidic	acidic	ADJ
ajst-20185	107	7	conditions	condition	NOUN
ajst-20185	107	8	,	,	PUNCT
ajst-20185	107	9	bacillus	bacillus	NOUN
ajst-20185	107	10	subtilis	subtili	NOUN
ajst-20185	107	11	enhances	enhance	VERB
ajst-20185	107	12	the	the	DET
ajst-20185	107	13	regulation	regulation	NOUN
ajst-20185	107	14	of	of	ADP
ajst-20185	107	15	genes	gene	NOUN
ajst-20185	107	16	associated	associate	VERB
ajst-20185	107	17	with	with	ADP
ajst-20185	107	18	transporter	transporter	NOUN
ajst-20185	107	19	activity	activity	NOUN
ajst-20185	107	20	to	to	PART
ajst-20185	107	21	facilitate	facilitate	VERB
ajst-20185	107	22	the	the	DET
ajst-20185	107	23	exchange	exchange	NOUN
ajst-20185	107	24	and	and	CCONJ
ajst-20185	107	25	equilibrium	equilibrium	NOUN
ajst-20185	107	26	of	of	ADP
ajst-20185	107	27	intracellular	intracellular	ADJ
ajst-20185	107	28	and	and	CCONJ
ajst-20185	107	29	extracellular	extracellular	ADJ
ajst-20185	107	30	substances	substance	NOUN
ajst-20185	107	31	,	,	PUNCT
ajst-20185	107	32	thereby	thereby	ADV
ajst-20185	107	33	maintaining	maintain	VERB
ajst-20185	107	34	normal	normal	ADJ
ajst-20185	107	35	physiological	physiological	ADJ
ajst-20185	107	36	functions	function	NOUN
ajst-20185	107	37	and	and	CCONJ
ajst-20185	107	38	metabolic	metabolic	NOUN
ajst-20185	107	39	activities	activity	NOUN
ajst-20185	107	40	within	within	ADP
ajst-20185	107	41	the	the	DET
ajst-20185	107	42	cell	cell	NOUN
ajst-20185	107	43	.	.	PUNCT
ajst-20185	108	1	in	in	ADP
ajst-20185	108	2	the	the	DET
ajst-20185	108	3	biological	biological	ADJ
ajst-20185	108	4	process	process	NOUN
ajst-20185	108	5	(	(	PUNCT
ajst-20185	108	6	bp	bp	PROPN
ajst-20185	108	7	)	)	PUNCT
ajst-20185	108	8	category	category	NOUN
ajst-20185	108	9	,	,	PUNCT
ajst-20185	108	10	significantly	significantly	ADV
ajst-20185	108	11	enriched	enrich	VERB
ajst-20185	109	1	go	go	NOUN
ajst-20185	109	2	terms	term	NOUN
ajst-20185	109	3	are	be	AUX
ajst-20185	109	4	associated	associate	VERB
ajst-20185	109	5	with	with	ADP
ajst-20185	109	6	compound	compound	NOUN
ajst-20185	109	7	transport	transport	NOUN
ajst-20185	109	8	and	and	CCONJ
ajst-20185	109	9	metabolic	metabolic	NOUN
ajst-20185	109	10	processes	process	NOUN
ajst-20185	109	11	,	,	PUNCT
ajst-20185	109	12	such	such	ADJ
ajst-20185	109	13	as	as	ADP
ajst-20185	109	14	"	"	PUNCT
ajst-20185	109	15	organic	organic	ADJ
ajst-20185	109	16	substance	substance	NOUN
ajst-20185	109	17	transport	transport	NOUN
ajst-20185	109	18	"	"	PUNCT
ajst-20185	109	19	(	(	PUNCT
ajst-20185	109	20	go:0071702	go:0071702	NUM
ajst-20185	109	21	)	)	PUNCT
ajst-20185	109	22	and	and	CCONJ
ajst-20185	109	23	"	"	PUNCT
ajst-20185	109	24	glutamine	glutamine	NOUN
ajst-20185	109	25	family	family	NOUN
ajst-20185	109	26	amino	amino	NOUN
ajst-20185	109	27	acid	acid	PROPN
ajst-20185	109	28	metabolic	metabolic	NOUN
ajst-20185	109	29	process	process	NOUN
ajst-20185	109	30	"	"	PUNCT
ajst-20185	109	31	(	(	PUNCT
ajst-20185	109	32	go:0009064	go:0009064	NOUN
ajst-20185	109	33	)	)	PUNCT
ajst-20185	109	34	.	.	PUNCT
ajst-20185	110	1	these	these	DET
ajst-20185	110	2	findings	finding	NOUN
ajst-20185	110	3	suggest	suggest	VERB
ajst-20185	110	4	that	that	SCONJ
ajst-20185	110	5	under	under	ADP
ajst-20185	110	6	acidic	acidic	ADJ
ajst-20185	110	7	conditions	condition	NOUN
ajst-20185	110	8	,	,	PUNCT
ajst-20185	110	9	bacillus	bacillus	NOUN
ajst-20185	110	10	subtilis	subtili	NOUN
ajst-20185	110	11	upregulates	upregulate	VERB
ajst-20185	110	12	the	the	DET
ajst-20185	110	13	regulation	regulation	NOUN
ajst-20185	110	14	of	of	ADP
ajst-20185	110	15	compound	compound	NOUN
ajst-20185	110	16	transport	transport	NOUN
ajst-20185	110	17	and	and	CCONJ
ajst-20185	110	18	metabolic	metabolic	NOUN
ajst-20185	110	19	processes	process	NOUN
ajst-20185	110	20	,	,	PUNCT
ajst-20185	110	21	thereby	thereby	ADV
ajst-20185	110	22	enhancing	enhance	VERB
ajst-20185	110	23	nutrient	nutrient	NOUN
ajst-20185	110	24	uptake	uptake	ADJ
ajst-20185	110	25	efficiency	efficiency	NOUN
ajst-20185	110	26	and	and	CCONJ
ajst-20185	110	27	utilization	utilization	NOUN
ajst-20185	110	28	while	while	SCONJ
ajst-20185	110	29	expediting	expedite	VERB
ajst-20185	110	30	the	the	DET
ajst-20185	110	31	excretion	excretion	NOUN
ajst-20185	110	32	of	of	ADP
ajst-20185	110	33	toxic	toxic	ADJ
ajst-20185	110	34	substances	substance	NOUN
ajst-20185	110	35	.	.	PUNCT
ajst-20185	111	1	this	this	PRON
ajst-20185	111	2	ultimately	ultimately	ADV
ajst-20185	111	3	contributes	contribute	VERB
ajst-20185	111	4	to	to	ADP
ajst-20185	111	5	improved	improved	ADJ
ajst-20185	111	6	cell	cell	NOUN
ajst-20185	111	7	survival	survival	NOUN
ajst-20185	111	8	and	and	CCONJ
ajst-20185	111	9	adaptability	adaptability	NOUN
ajst-20185	111	10	.	.	PUNCT
ajst-20185	112	1	59	59	NUM
ajst-20185	112	2	figure	figure	NOUN
ajst-20185	112	3	3	3	NUM
ajst-20185	112	4	-	-	SYM
ajst-20185	112	5	3	3	NUM
ajst-20185	112	6	.	.	NUM
ajst-20185	112	7	go	go	VERB
ajst-20185	112	8	enrichment	enrichment	NOUN
ajst-20185	112	9	analysis	analysis	NOUN
ajst-20185	112	10	histogram	histogram	NOUN
ajst-20185	112	11	in	in	ADP
ajst-20185	112	12	conclusion	conclusion	NOUN
ajst-20185	112	13	,	,	PUNCT
ajst-20185	112	14	our	our	PRON
ajst-20185	112	15	go	go	NOUN
ajst-20185	112	16	enrichment	enrichment	NOUN
ajst-20185	112	17	analysis	analysis	NOUN
ajst-20185	112	18	of	of	ADP
ajst-20185	112	19	the	the	DET
ajst-20185	112	20	transcriptome	transcriptome	NOUN
ajst-20185	112	21	has	have	AUX
ajst-20185	112	22	revealed	reveal	VERB
ajst-20185	112	23	crucial	crucial	ADJ
ajst-20185	112	24	mechanisms	mechanism	NOUN
ajst-20185	112	25	underlying	underlie	VERB
ajst-20185	112	26	the	the	DET
ajst-20185	112	27	adaptive	adaptive	ADJ
ajst-20185	112	28	evolution	evolution	NOUN
ajst-20185	112	29	of	of	ADP
ajst-20185	112	30	bacillus	bacillus	NOUN
ajst-20185	112	31	subtilis	subtili	NOUN
ajst-20185	112	32	168	168	NUM
ajst-20185	112	33	in	in	ADP
ajst-20185	112	34	response	response	NOUN
ajst-20185	112	35	to	to	ADP
ajst-20185	112	36	low	low	ADJ
ajst-20185	112	37	ph	ph	ADJ
ajst-20185	112	38	conditions	condition	NOUN
ajst-20185	112	39	.	.	PUNCT
ajst-20185	113	1	these	these	DET
ajst-20185	113	2	mechanisms	mechanism	NOUN
ajst-20185	113	3	primarily	primarily	ADV
ajst-20185	113	4	involve	involve	VERB
ajst-20185	113	5	the	the	DET
ajst-20185	113	6	enhancement	enhancement	NOUN
ajst-20185	113	7	of	of	ADP
ajst-20185	113	8	cell	cell	NOUN
ajst-20185	113	9	membrane	membrane	NOUN
ajst-20185	113	10	structure	structure	NOUN
ajst-20185	113	11	and	and	CCONJ
ajst-20185	113	12	regulation	regulation	NOUN
ajst-20185	113	13	of	of	ADP
ajst-20185	113	14	function	function	NOUN
ajst-20185	113	15	to	to	PART
ajst-20185	113	16	maintain	maintain	VERB
ajst-20185	113	17	cellular	cellular	ADJ
ajst-20185	113	18	stability	stability	NOUN
ajst-20185	113	19	,	,	PUNCT
ajst-20185	113	20	upregulation	upregulation	NOUN
ajst-20185	113	21	of	of	ADP
ajst-20185	113	22	transporter	transporter	NOUN
ajst-20185	113	23	activity	activity	NOUN
ajst-20185	113	24	-	-	PUNCT
ajst-20185	113	25	related	relate	VERB
ajst-20185	113	26	gene	gene	NOUN
ajst-20185	113	27	expression	expression	NOUN
ajst-20185	113	28	to	to	PART
ajst-20185	113	29	facilitate	facilitate	VERB
ajst-20185	113	30	material	material	NOUN
ajst-20185	113	31	exchange	exchange	NOUN
ajst-20185	113	32	and	and	CCONJ
ajst-20185	113	33	homeostasis	homeostasis	NOUN
ajst-20185	113	34	,	,	PUNCT
ajst-20185	113	35	and	and	CCONJ
ajst-20185	113	36	reinforcement	reinforcement	NOUN
ajst-20185	113	37	of	of	ADP
ajst-20185	113	38	compound	compound	NOUN
ajst-20185	113	39	transport	transport	NOUN
ajst-20185	113	40	and	and	CCONJ
ajst-20185	113	41	metabolic	metabolic	NOUN
ajst-20185	113	42	process	process	NOUN
ajst-20185	113	43	regulation	regulation	NOUN
ajst-20185	113	44	to	to	PART
ajst-20185	113	45	improve	improve	VERB
ajst-20185	113	46	cell	cell	NOUN
ajst-20185	113	47	survival	survival	NOUN
ajst-20185	113	48	and	and	CCONJ
ajst-20185	113	49	adaptability	adaptability	NOUN
ajst-20185	113	50	.	.	PUNCT
ajst-20185	114	1	these	these	DET
ajst-20185	114	2	coordinated	coordinate	VERB
ajst-20185	114	3	adaptive	adaptive	ADJ
ajst-20185	114	4	changes	change	NOUN
ajst-20185	114	5	enable	enable	VERB
ajst-20185	114	6	bacillus	bacillus	NOUN
ajst-20185	114	7	subtilis	subtili	NOUN
ajst-20185	114	8	to	to	PART
ajst-20185	114	9	better	well	ADV
ajst-20185	114	10	cope	cope	VERB
ajst-20185	114	11	with	with	ADP
ajst-20185	114	12	acidic	acidic	ADJ
ajst-20185	114	13	stress	stress	NOUN
ajst-20185	114	14	,	,	PUNCT
ajst-20185	114	15	sustaining	sustain	VERB
ajst-20185	114	16	normal	normal	ADJ
ajst-20185	114	17	growth	growth	NOUN
ajst-20185	114	18	and	and	CCONJ
ajst-20185	114	19	metabolic	metabolic	NOUN
ajst-20185	114	20	activities	activity	NOUN
ajst-20185	114	21	in	in	ADP
ajst-20185	114	22	a	a	DET
ajst-20185	114	23	low	low	ADJ
ajst-20185	114	24	ph	ph	ADJ
ajst-20185	114	25	environment	environment	NOUN
ajst-20185	114	26	.	.	PUNCT
ajst-20185	115	1	future	future	ADJ
ajst-20185	115	2	research	research	NOUN
ajst-20185	115	3	can	can	AUX
ajst-20185	115	4	further	far	ADV
ajst-20185	115	5	explore	explore	VERB
ajst-20185	115	6	the	the	DET
ajst-20185	115	7	specific	specific	ADJ
ajst-20185	115	8	mechanistic	mechanistic	ADJ
ajst-20185	115	9	roles	role	NOUN
ajst-20185	115	10	and	and	CCONJ
ajst-20185	115	11	regulatory	regulatory	ADJ
ajst-20185	115	12	networks	network	NOUN
ajst-20185	115	13	of	of	ADP
ajst-20185	115	14	these	these	DET
ajst-20185	115	15	key	key	ADJ
ajst-20185	115	16	genes	gene	NOUN
ajst-20185	115	17	and	and	CCONJ
ajst-20185	115	18	pathways	pathway	NOUN
ajst-20185	115	19	in	in	ADP
ajst-20185	115	20	the	the	DET
ajst-20185	115	21	process	process	NOUN
ajst-20185	115	22	of	of	ADP
ajst-20185	115	23	adaptive	adaptive	ADJ
ajst-20185	115	24	evolution	evolution	NOUN
ajst-20185	115	25	.	.	PUNCT
ajst-20185	116	1	4	4	X
ajst-20185	116	2	.	.	X
ajst-20185	116	3	conclusion	conclusion	NOUN
ajst-20185	116	4	in	in	ADP
ajst-20185	116	5	this	this	DET
ajst-20185	116	6	study	study	NOUN
ajst-20185	116	7	,	,	PUNCT
ajst-20185	116	8	we	we	PRON
ajst-20185	116	9	successfully	successfully	ADV
ajst-20185	116	10	identified	identify	VERB
ajst-20185	116	11	acid	acid	ADJ
ajst-20185	116	12	-	-	PUNCT
ajst-20185	116	13	tolerant	tolerant	ADJ
ajst-20185	116	14	strains	strain	NOUN
ajst-20185	116	15	of	of	ADP
ajst-20185	116	16	bacillus	bacillus	NOUN
ajst-20185	116	17	subtilis	subtili	NOUN
ajst-20185	116	18	168	168	NUM
ajst-20185	116	19	through	through	ADP
ajst-20185	116	20	induced	induce	VERB
ajst-20185	116	21	adaptive	adaptive	ADJ
ajst-20185	116	22	evolution	evolution	NOUN
ajst-20185	116	23	under	under	ADP
ajst-20185	116	24	acidic	acidic	ADJ
ajst-20185	116	25	conditions	condition	NOUN
ajst-20185	116	26	.	.	PUNCT
ajst-20185	117	1	these	these	DET
ajst-20185	117	2	strains	strain	NOUN
ajst-20185	117	3	demonstrated	demonstrate	VERB
ajst-20185	117	4	significant	significant	ADJ
ajst-20185	117	5	growth	growth	NOUN
ajst-20185	117	6	advantages	advantage	NOUN
ajst-20185	117	7	in	in	ADP
ajst-20185	117	8	low	low	ADJ
ajst-20185	117	9	-	-	PUNCT
ajst-20185	117	10	ph	ph	ADJ
ajst-20185	117	11	media	medium	NOUN
ajst-20185	117	12	.	.	PUNCT
ajst-20185	118	1	to	to	PART
ajst-20185	118	2	further	far	ADV
ajst-20185	118	3	elucidate	elucidate	VERB
ajst-20185	118	4	their	their	PRON
ajst-20185	118	5	mechanisms	mechanism	NOUN
ajst-20185	118	6	of	of	ADP
ajst-20185	118	7	acid	acid	NOUN
ajst-20185	118	8	tolerance	tolerance	NOUN
ajst-20185	118	9	,	,	PUNCT
ajst-20185	118	10	we	we	PRON
ajst-20185	118	11	conducted	conduct	VERB
ajst-20185	118	12	transcriptome	transcriptome	ADJ
ajst-20185	118	13	sequencing	sequence	VERB
ajst-20185	118	14	analysis	analysis	NOUN
ajst-20185	118	15	.	.	PUNCT
ajst-20185	119	1	the	the	DET
ajst-20185	119	2	kegg	kegg	NOUN
ajst-20185	119	3	enrichment	enrichment	NOUN
ajst-20185	119	4	analysis	analysis	NOUN
ajst-20185	119	5	results	result	NOUN
ajst-20185	119	6	revealed	reveal	VERB
ajst-20185	119	7	that	that	SCONJ
ajst-20185	119	8	the	the	DET
ajst-20185	119	9	primary	primary	ADJ
ajst-20185	119	10	adaptive	adaptive	ADJ
ajst-20185	119	11	strategy	strategy	NOUN
ajst-20185	119	12	of	of	ADP
ajst-20185	119	13	bacillus	bacillus	NOUN
ajst-20185	119	14	subtilis	subtili	NOUN
ajst-20185	119	15	in	in	ADP
ajst-20185	119	16	low	low	ADJ
ajst-20185	119	17	ph	ph	ADJ
ajst-20185	119	18	conditions	condition	NOUN
ajst-20185	119	19	involves	involve	VERB
ajst-20185	119	20	restructuring	restructure	VERB
ajst-20185	119	21	its	its	PRON
ajst-20185	119	22	metabolic	metabolic	NOUN
ajst-20185	119	23	network	network	NOUN
ajst-20185	119	24	.	.	PUNCT
ajst-20185	120	1	particularly	particularly	ADV
ajst-20185	120	2	,	,	PUNCT
ajst-20185	120	3	there	there	PRON
ajst-20185	120	4	was	be	VERB
ajst-20185	120	5	a	a	DET
ajst-20185	120	6	significant	significant	ADJ
ajst-20185	120	7	enhancement	enhancement	NOUN
ajst-20185	120	8	in	in	ADP
ajst-20185	120	9	amino	amino	NOUN
ajst-20185	120	10	acid	acid	NOUN
ajst-20185	120	11	metabolism	metabolism	NOUN
ajst-20185	120	12	and	and	CCONJ
ajst-20185	120	13	biosynthetic	biosynthetic	ADJ
ajst-20185	120	14	pathways	pathway	NOUN
ajst-20185	120	15	,	,	PUNCT
ajst-20185	120	16	which	which	PRON
ajst-20185	120	17	play	play	VERB
ajst-20185	120	18	a	a	DET
ajst-20185	120	19	crucial	crucial	ADJ
ajst-20185	120	20	role	role	NOUN
ajst-20185	120	21	in	in	ADP
ajst-20185	120	22	maintaining	maintain	VERB
ajst-20185	120	23	normal	normal	ADJ
ajst-20185	120	24	physiological	physiological	ADJ
ajst-20185	120	25	functions	function	NOUN
ajst-20185	120	26	and	and	CCONJ
ajst-20185	120	27	ensuring	ensure	VERB
ajst-20185	120	28	cell	cell	NOUN
ajst-20185	120	29	survival	survival	NOUN
ajst-20185	120	30	in	in	ADP
ajst-20185	120	31	an	an	DET
ajst-20185	120	32	acidic	acidic	ADJ
ajst-20185	120	33	environment	environment	NOUN
ajst-20185	120	34	.	.	PUNCT
ajst-20185	121	1	through	through	AUX
ajst-20185	121	2	go	go	VERB
ajst-20185	121	3	enrichment	enrichment	NOUN
ajst-20185	121	4	analysis	analysis	NOUN
ajst-20185	121	5	of	of	ADP
ajst-20185	121	6	the	the	DET
ajst-20185	121	7	transcriptome	transcriptome	NOUN
ajst-20185	121	8	,	,	PUNCT
ajst-20185	121	9	we	we	PRON
ajst-20185	121	10	observed	observe	VERB
ajst-20185	121	11	significant	significant	ADJ
ajst-20185	121	12	enrichment	enrichment	NOUN
ajst-20185	121	13	of	of	ADP
ajst-20185	121	14	differentially	differentially	ADV
ajst-20185	121	15	expressed	express	VERB
ajst-20185	121	16	genes	gene	NOUN
ajst-20185	121	17	in	in	ADP
ajst-20185	121	18	cellular	cellular	ADJ
ajst-20185	121	19	components	component	NOUN
ajst-20185	121	20	,	,	PUNCT
ajst-20185	121	21	molecular	molecular	ADJ
ajst-20185	121	22	functions	function	NOUN
ajst-20185	121	23	,	,	PUNCT
ajst-20185	121	24	and	and	CCONJ
ajst-20185	121	25	biological	biological	ADJ
ajst-20185	121	26	processes	process	NOUN
ajst-20185	121	27	.	.	PUNCT
ajst-20185	122	1	specifically	specifically	ADV
ajst-20185	122	2	,	,	PUNCT
ajst-20185	122	3	under	under	ADP
ajst-20185	122	4	low	low	ADJ
ajst-20185	122	5	ph	ph	ADJ
ajst-20185	122	6	stress	stress	NOUN
ajst-20185	122	7	conditions	condition	NOUN
ajst-20185	122	8	,	,	PUNCT
ajst-20185	122	9	bacillus	bacillus	NOUN
ajst-20185	122	10	subtilis	subtili	NOUN
ajst-20185	122	11	upregulated	upregulate	VERB
ajst-20185	122	12	the	the	DET
ajst-20185	122	13	expression	expression	NOUN
ajst-20185	122	14	of	of	ADP
ajst-20185	122	15	genes	gene	NOUN
ajst-20185	122	16	associated	associate	VERB
ajst-20185	122	17	with	with	ADP
ajst-20185	122	18	cell	cell	NOUN
ajst-20185	122	19	membrane	membrane	NOUN
ajst-20185	122	20	structure	structure	NOUN
ajst-20185	122	21	and	and	CCONJ
ajst-20185	122	22	function	function	NOUN
ajst-20185	122	23	,	,	PUNCT
ajst-20185	122	24	transporter	transporter	NOUN
ajst-20185	122	25	activity	activity	NOUN
ajst-20185	122	26	,	,	PUNCT
ajst-20185	122	27	and	and	CCONJ
ajst-20185	122	28	compound	compound	NOUN
ajst-20185	122	29	transport	transport	NOUN
ajst-20185	122	30	and	and	CCONJ
ajst-20185	122	31	metabolic	metabolic	NOUN
ajst-20185	122	32	processes	process	NOUN
ajst-20185	122	33	.	.	PUNCT
ajst-20185	123	1	the	the	DET
ajst-20185	123	2	upregulation	upregulation	NOUN
ajst-20185	123	3	of	of	ADP
ajst-20185	123	4	these	these	DET
ajst-20185	123	5	genes	gene	NOUN
ajst-20185	123	6	contributes	contribute	VERB
ajst-20185	123	7	to	to	ADP
ajst-20185	123	8	enhancing	enhance	VERB
ajst-20185	123	9	cellular	cellular	ADJ
ajst-20185	123	10	tolerance	tolerance	NOUN
ajst-20185	123	11	and	and	CCONJ
ajst-20185	123	12	adaptability	adaptability	NOUN
ajst-20185	123	13	,	,	PUNCT
ajst-20185	123	14	enabling	enable	VERB
ajst-20185	123	15	the	the	DET
ajst-20185	123	16	bacterium	bacterium	NOUN
ajst-20185	123	17	to	to	PART
ajst-20185	123	18	maintain	maintain	VERB
ajst-20185	123	19	cell	cell	NOUN
ajst-20185	123	20	stability	stability	NOUN
ajst-20185	123	21	,	,	PUNCT
ajst-20185	123	22	promote	promote	VERB
ajst-20185	123	23	material	material	NOUN
ajst-20185	123	24	exchange	exchange	NOUN
ajst-20185	123	25	and	and	CCONJ
ajst-20185	123	26	homeostasis	homeostasis	NOUN
ajst-20185	123	27	,	,	PUNCT
ajst-20185	123	28	and	and	CCONJ
ajst-20185	123	29	improve	improve	VERB
ajst-20185	123	30	the	the	DET
ajst-20185	123	31	uptake	uptake	NOUN
ajst-20185	123	32	and	and	CCONJ
ajst-20185	123	33	utilization	utilization	NOUN
ajst-20185	123	34	efficiency	efficiency	NOUN
ajst-20185	123	35	of	of	ADP
ajst-20185	123	36	nutrients	nutrient	NOUN
ajst-20185	123	37	in	in	ADP
ajst-20185	123	38	an	an	DET
ajst-20185	123	39	acidic	acidic	ADJ
ajst-20185	123	40	environment	environment	NOUN
ajst-20185	123	41	.	.	PUNCT
ajst-20185	124	1	in	in	ADP
ajst-20185	124	2	conclusion	conclusion	NOUN
ajst-20185	124	3	,	,	PUNCT
ajst-20185	124	4	this	this	DET
ajst-20185	124	5	study	study	NOUN
ajst-20185	124	6	not	not	PART
ajst-20185	124	7	only	only	ADV
ajst-20185	124	8	provides	provide	VERB
ajst-20185	124	9	valuable	valuable	ADJ
ajst-20185	124	10	insights	insight	NOUN
ajst-20185	124	11	into	into	ADP
ajst-20185	124	12	the	the	DET
ajst-20185	124	13	adaptive	adaptive	ADJ
ajst-20185	124	14	mechanisms	mechanism	NOUN
ajst-20185	124	15	of	of	ADP
ajst-20185	124	16	microorganisms	microorganism	NOUN
ajst-20185	124	17	in	in	ADP
ajst-20185	124	18	extreme	extreme	ADJ
ajst-20185	124	19	environmental	environmental	ADJ
ajst-20185	124	20	conditions	condition	NOUN
ajst-20185	124	21	but	but	CCONJ
ajst-20185	124	22	also	also	ADV
ajst-20185	124	23	identifies	identify	VERB
ajst-20185	124	24	potential	potential	ADJ
ajst-20185	124	25	targets	target	NOUN
ajst-20185	124	26	for	for	ADP
ajst-20185	124	27	enhancing	enhance	VERB
ajst-20185	124	28	and	and	CCONJ
ajst-20185	124	29	optimizing	optimize	VERB
ajst-20185	124	30	industrial	industrial	ADJ
ajst-20185	124	31	microbial	microbial	ADJ
ajst-20185	124	32	strains	strain	NOUN
ajst-20185	124	33	.	.	PUNCT
ajst-20185	125	1	these	these	DET
ajst-20185	125	2	findings	finding	NOUN
ajst-20185	125	3	will	will	AUX
ajst-20185	125	4	facilitate	facilitate	VERB
ajst-20185	125	5	the	the	DET
ajst-20185	125	6	development	development	NOUN
ajst-20185	125	7	of	of	ADP
ajst-20185	125	8	more	more	ADV
ajst-20185	125	9	efficient	efficient	ADJ
ajst-20185	125	10	and	and	CCONJ
ajst-20185	125	11	resilient	resilient	ADJ
ajst-20185	125	12	industrial	industrial	ADJ
ajst-20185	125	13	microbial	microbial	ADJ
ajst-20185	125	14	strains	strain	NOUN
ajst-20185	125	15	capable	capable	ADJ
ajst-20185	125	16	of	of	ADP
ajst-20185	125	17	adapting	adapt	VERB
ajst-20185	125	18	to	to	PART
ajst-20185	125	19	diverse	diverse	VERB
ajst-20185	125	20	extreme	extreme	ADJ
ajst-20185	125	21	environmental	environmental	ADJ
ajst-20185	125	22	conditions	condition	NOUN
ajst-20185	125	23	.	.	PUNCT
ajst-20185	126	1	references	reference	NOUN
ajst-20185	126	2	[	[	X
ajst-20185	126	3	1	1	NUM
ajst-20185	126	4	]	]	PUNCT
ajst-20185	126	5	aesn	aesn	PROPN
ajst-20185	126	6	,	,	PUNCT
ajst-20185	126	7	eaa	eaa	PROPN
ajst-20185	126	8	,	,	PUNCT
ajst-20185	126	9	sas	sas	PROPN
ajst-20185	126	10	,	,	PUNCT
ajst-20185	126	11	et	et	PROPN
ajst-20185	126	12	al	al	PROPN
ajst-20185	126	13	.	.	PROPN
ajst-20185	126	14	antibacterial	antibacterial	ADJ
ajst-20185	126	15	and	and	CCONJ
ajst-20185	126	16	anticancer	anticancer	NOUN
ajst-20185	126	17	activity	activity	NOUN
ajst-20185	126	18	of	of	ADP
ajst-20185	126	19	ε	ε	NOUN
ajst-20185	126	20	-	-	PUNCT
ajst-20185	126	21	poly	poly	ADJ
ajst-20185	126	22	-	-	PUNCT
ajst-20185	126	23	l	l	NOUN
ajst-20185	126	24	-	-	NOUN
ajst-20185	126	25	lysine	lysine	NOUN
ajst-20185	126	26	(	(	PUNCT
ajst-20185	126	27	ε	ε	PROPN
ajst-20185	126	28	-	-	PUNCT
ajst-20185	126	29	pl	pl	NOUN
ajst-20185	126	30	)	)	PUNCT
ajst-20185	126	31	produced	produce	VERB
ajst-20185	126	32	by	by	ADP
ajst-20185	126	33	a	a	DET
ajst-20185	126	34	marine	marine	ADJ
ajst-20185	126	35	bacillus	bacillus	NOUN
ajst-20185	126	36	subtilis	subtili	NOUN
ajst-20185	126	37	sp.[j	sp.[j	VERB
ajst-20185	126	38	]	]	PUNCT
ajst-20185	126	39	.	.	PUNCT
ajst-20185	127	1	journal	journal	PROPN
ajst-20185	127	2	of	of	ADP
ajst-20185	127	3	basic	basic	ADJ
ajst-20185	127	4	microbiology	microbiology	NOUN
ajst-20185	127	5	,	,	PUNCT
ajst-20185	127	6	2012	2012	NUM
ajst-20185	127	7	,	,	PUNCT
ajst-20185	127	8	52(5	52(5	NUM
ajst-20185	127	9	)	)	PUNCT
ajst-20185	127	10	.	.	PUNCT
ajst-20185	128	1	[	[	X
ajst-20185	128	2	2	2	NUM
ajst-20185	128	3	]	]	PUNCT
ajst-20185	128	4	westers	westers	PROPN
ajst-20185	128	5	l	l	PROPN
ajst-20185	128	6	,	,	PUNCT
ajst-20185	128	7	westers	westers	PROPN
ajst-20185	128	8	h	h	NOUN
ajst-20185	128	9	,	,	PUNCT
ajst-20185	128	10	quax	quax	PROPN
ajst-20185	128	11	w	w	PROPN
ajst-20185	128	12	j.	j.	PROPN
ajst-20185	128	13	bacillus	bacillus	NOUN
ajst-20185	128	14	subtilis	subtili	NOUN
ajst-20185	128	15	as	as	ADP
ajst-20185	128	16	cell	cell	NOUN
ajst-20185	128	17	factory	factory	NOUN
ajst-20185	128	18	for	for	ADP
ajst-20185	128	19	pharmaceutical	pharmaceutical	ADJ
ajst-20185	128	20	proteins	protein	NOUN
ajst-20185	128	21	:	:	PUNCT
ajst-20185	128	22	a	a	DET
ajst-20185	128	23	biotechnological	biotechnological	ADJ
ajst-20185	128	24	approach	approach	NOUN
ajst-20185	128	25	to	to	PART
ajst-20185	128	26	optimize	optimize	VERB
ajst-20185	128	27	the	the	DET
ajst-20185	128	28	host	host	NOUN
ajst-20185	128	29	organism[j	organism[j	NOUN
ajst-20185	128	30	]	]	PUNCT
ajst-20185	128	31	.	.	PUNCT
ajst-20185	129	1	biochim	biochim	PROPN
ajst-20185	129	2	biophys	biophy	NOUN
ajst-20185	129	3	acta	acta	PROPN
ajst-20185	129	4	,	,	PUNCT
ajst-20185	129	5	2004	2004	NUM
ajst-20185	129	6	,	,	PUNCT
ajst-20185	129	7	1694(1	1694(1	NOUN
ajst-20185	129	8	-	-	SYM
ajst-20185	129	9	3	3	NUM
ajst-20185	129	10	):	):	PUNCT
ajst-20185	129	11	299	299	NUM
ajst-20185	129	12	-	-	SYM
ajst-20185	129	13	310	310	NUM
ajst-20185	129	14	.	.	PUNCT
ajst-20185	130	1	[	[	X
ajst-20185	130	2	3	3	NUM
ajst-20185	130	3	]	]	X
ajst-20185	130	4	yonghua	yonghua	PROPN
ajst-20185	130	5	s.	s.	PROPN
ajst-20185	130	6	expression	expression	NOUN
ajst-20185	130	7	and	and	CCONJ
ajst-20185	130	8	character	character	NOUN
ajst-20185	130	9	of	of	ADP
ajst-20185	130	10	three	three	NUM
ajst-20185	130	11	plasmids	plasmid	NOUN
ajst-20185	130	12	from	from	ADP
ajst-20185	130	13	staphylococcus	staphylococcus	NOUN
ajst-20185	130	14	aureus	aureus	NOUN
ajst-20185	130	15	strain	strain	VERB
ajst-20185	130	16	307	307	NUM
ajst-20185	130	17	in	in	ADP
ajst-20185	130	18	bacillus	bacillus	NOUN
ajst-20185	130	19	sttbtilis	sttbtili	NOUN
ajst-20185	130	20	strains	strain	VERB
ajst-20185	130	21	ki-2	ki-2	PUNCT
ajst-20185	130	22	and	and	CCONJ
ajst-20185	130	23	168[j	168[j	NUM
ajst-20185	130	24	]	]	PUNCT
ajst-20185	130	25	.	.	PUNCT
ajst-20185	131	1	acta	acta	PROPN
ajst-20185	131	2	genetica	genetica	PROPN
ajst-20185	131	3	sinica	sinica	PROPN
ajst-20185	131	4	,	,	PUNCT
ajst-20185	131	5	1983	1983	NUM
ajst-20185	131	6	.	.	PUNCT
ajst-20185	132	1	60	60	NUM
ajst-20185	133	1	[	[	SYM
ajst-20185	133	2	4	4	X
ajst-20185	133	3	]	]	X
ajst-20185	133	4	koo	koo	PROPN
ajst-20185	133	5	b	b	PROPN
ajst-20185	133	6	m	m	PROPN
ajst-20185	133	7	,	,	PUNCT
ajst-20185	133	8	kritikos	kritikos	ADV
ajst-20185	133	9	g	g	PROPN
ajst-20185	133	10	,	,	PUNCT
ajst-20185	133	11	farelli	farelli	PROPN
ajst-20185	133	12	j	j	PROPN
ajst-20185	134	1	d	d	PROPN
ajst-20185	134	2	,	,	PUNCT
ajst-20185	134	3	et	et	PROPN
ajst-20185	134	4	al	al	PROPN
ajst-20185	134	5	.	.	PUNCT
ajst-20185	134	6	construction	construction	NOUN
ajst-20185	134	7	and	and	CCONJ
ajst-20185	134	8	analysis	analysis	NOUN
ajst-20185	134	9	of	of	ADP
ajst-20185	134	10	two	two	NUM
ajst-20185	134	11	genome	genome	NOUN
ajst-20185	134	12	-	-	PUNCT
ajst-20185	134	13	scale	scale	NOUN
ajst-20185	134	14	deletion	deletion	NOUN
ajst-20185	134	15	libraries	library	NOUN
ajst-20185	134	16	for	for	ADP
ajst-20185	134	17	bacillus	bacillus	NOUN
ajst-20185	134	18	subtilis[j	subtilis[j	NOUN
ajst-20185	134	19	]	]	PUNCT
ajst-20185	134	20	.	.	PUNCT
ajst-20185	135	1	cell	cell	NOUN
ajst-20185	135	2	syst	syst	PROPN
ajst-20185	135	3	,	,	PUNCT
ajst-20185	135	4	2017	2017	NUM
ajst-20185	135	5	,	,	PUNCT
ajst-20185	135	6	4(3	4(3	NUM
ajst-20185	135	7	):	):	PUNCT
ajst-20185	135	8	291	291	NUM
ajst-20185	135	9	-	-	SYM
ajst-20185	135	10	305	305	NUM
ajst-20185	135	11	.	.	PUNCT
ajst-20185	136	1	[	[	X
ajst-20185	136	2	5	5	NUM
ajst-20185	136	3	]	]	X
ajst-20185	136	4	zhao	zhao	NOUN
ajst-20185	136	5	x	x	SYM
ajst-20185	136	6	y	y	PROPN
ajst-20185	136	7	,	,	PUNCT
ajst-20185	136	8	xu	xu	PROPN
ajst-20185	136	9	j	j	PROPN
ajst-20185	137	1	y	y	PROPN
ajst-20185	137	2	,	,	PUNCT
ajst-20185	137	3	tan	tan	PROPN
ajst-20185	137	4	m	m	PROPN
ajst-20185	137	5	,	,	PUNCT
ajst-20185	137	6	et	et	PROPN
ajst-20185	137	7	al	al	PROPN
ajst-20185	137	8	.	.	PUNCT
ajst-20185	138	1	construction	construction	NOUN
ajst-20185	138	2	of	of	ADP
ajst-20185	138	3	a	a	DET
ajst-20185	138	4	plasmid	plasmid	ADJ
ajst-20185	138	5	interspecific	interspecific	ADJ
ajst-20185	138	6	transfer	transfer	NOUN
ajst-20185	138	7	system	system	NOUN
ajst-20185	138	8	in	in	ADP
ajst-20185	138	9	bacillus	bacillus	NOUN
ajst-20185	138	10	species	specie	NOUN
ajst-20185	138	11	with	with	ADP
ajst-20185	138	12	the	the	DET
ajst-20185	138	13	counter	counter	ADJ
ajst-20185	138	14	-	-	ADJ
ajst-20185	138	15	selectable	selectable	ADJ
ajst-20185	138	16	marker	marker	NOUN
ajst-20185	138	17	mazf[j	mazf[j	NOUN
ajst-20185	138	18	]	]	PUNCT
ajst-20185	138	19	.	.	PUNCT
ajst-20185	139	1	journal	journal	PROPN
ajst-20185	139	2	of	of	ADP
ajst-20185	139	3	industrial	industrial	ADJ
ajst-20185	139	4	microbiology	microbiology	NOUN
ajst-20185	139	5	&	&	CCONJ
ajst-20185	139	6	biotechnology	biotechnology	NOUN
ajst-20185	139	7	,	,	PUNCT
ajst-20185	139	8	2018	2018	NUM
ajst-20185	139	9	.	.	PUNCT
ajst-20185	140	1	[	[	X
ajst-20185	140	2	6	6	NUM
ajst-20185	140	3	]	]	X
ajst-20185	140	4	sandberg	sandberg	PROPN
ajst-20185	140	5	t	t	PROPN
ajst-20185	140	6	e	e	PROPN
ajst-20185	140	7	,	,	PUNCT
ajst-20185	140	8	salazar	salazar	PROPN
ajst-20185	140	9	m	m	PROPN
ajst-20185	140	10	j	j	PROPN
ajst-20185	140	11	,	,	PUNCT
ajst-20185	140	12	weng	weng	PROPN
ajst-20185	140	13	l	l	PROPN
ajst-20185	140	14	l	l	PROPN
ajst-20185	140	15	,	,	PUNCT
ajst-20185	140	16	et	et	PROPN
ajst-20185	140	17	al	al	PROPN
ajst-20185	140	18	.	.	PUNCT
ajst-20185	141	1	the	the	DET
ajst-20185	141	2	emergence	emergence	NOUN
ajst-20185	141	3	of	of	ADP
ajst-20185	141	4	adaptive	adaptive	ADJ
ajst-20185	141	5	laboratory	laboratory	NOUN
ajst-20185	141	6	evolution	evolution	NOUN
ajst-20185	141	7	as	as	ADP
ajst-20185	141	8	an	an	DET
ajst-20185	141	9	efficient	efficient	ADJ
ajst-20185	141	10	tool	tool	NOUN
ajst-20185	141	11	for	for	ADP
ajst-20185	141	12	biological	biological	ADJ
ajst-20185	141	13	discovery	discovery	NOUN
ajst-20185	141	14	and	and	CCONJ
ajst-20185	141	15	industrial	industrial	ADJ
ajst-20185	141	16	biotechnology[j	biotechnology[j	NOUN
ajst-20185	141	17	]	]	PUNCT
ajst-20185	141	18	.	.	PUNCT
ajst-20185	142	1	metabolic	metabolic	PROPN
ajst-20185	142	2	engineering	engineering	NOUN
ajst-20185	142	3	,	,	PUNCT
ajst-20185	142	4	2019	2019	NUM
ajst-20185	142	5	,	,	PUNCT
ajst-20185	142	6	56	56	NUM
ajst-20185	142	7	.	.	PUNCT
ajst-20185	143	1	[	[	X
ajst-20185	143	2	7	7	NUM
ajst-20185	143	3	]	]	X
ajst-20185	143	4	wu	wu	PROPN
ajst-20185	143	5	y	y	PROPN
ajst-20185	143	6	,	,	PUNCT
ajst-20185	143	7	jameel	jameel	PROPN
ajst-20185	143	8	a	a	PROPN
ajst-20185	143	9	,	,	PUNCT
ajst-20185	143	10	xing	xing	PROPN
ajst-20185	143	11	xh	xh	PROPN
ajst-20185	143	12	,	,	PUNCT
ajst-20185	143	13	et	et	PROPN
ajst-20185	143	14	al	al	PROPN
ajst-20185	143	15	.	.	PROPN
ajst-20185	144	1	advanced	advanced	ADJ
ajst-20185	144	2	strategies	strategy	NOUN
ajst-20185	144	3	and	and	CCONJ
ajst-20185	144	4	tools	tool	NOUN
ajst-20185	144	5	to	to	PART
ajst-20185	144	6	facilitate	facilitate	VERB
ajst-20185	144	7	and	and	CCONJ
ajst-20185	144	8	streamline	streamline	VERB
ajst-20185	144	9	microbial	microbial	ADJ
ajst-20185	144	10	adaptive	adaptive	ADJ
ajst-20185	144	11	laboratory	laboratory	NOUN
ajst-20185	144	12	evolution.[j	evolution.[j	PROPN
ajst-20185	144	13	]	]	PUNCT
ajst-20185	144	14	.	.	PUNCT
ajst-20185	145	1	trends	trend	NOUN
ajst-20185	145	2	in	in	ADP
ajst-20185	145	3	biotechnology	biotechnology	NOUN
ajst-20185	145	4	,	,	PUNCT
ajst-20185	145	5	2021	2021	NUM
ajst-20185	145	6	.	.	PUNCT
ajst-20185	146	1	[	[	X
ajst-20185	146	2	8	8	NUM
ajst-20185	146	3	]	]	X
ajst-20185	146	4	gibson	gibson	PROPN
ajst-20185	146	5	b	b	PROPN
ajst-20185	146	6	,	,	PUNCT
ajst-20185	146	7	dahabieh	dahabieh	PROPN
ajst-20185	146	8	m	m	PROPN
ajst-20185	146	9	,	,	PUNCT
ajst-20185	146	10	krogerus	krogerus	PROPN
ajst-20185	146	11	k	k	PROPN
ajst-20185	146	12	,	,	PUNCT
ajst-20185	146	13	et	et	PROPN
ajst-20185	146	14	al	al	PROPN
ajst-20185	146	15	.	.	PROPN
ajst-20185	146	16	adaptive	adaptive	PROPN
ajst-20185	146	17	laboratory	laboratory	NOUN
ajst-20185	146	18	evolution	evolution	NOUN
ajst-20185	146	19	of	of	ADP
ajst-20185	146	20	ale	ale	NOUN
ajst-20185	146	21	and	and	CCONJ
ajst-20185	146	22	lager	lager	NOUN
ajst-20185	146	23	yeasts	yeast	NOUN
ajst-20185	146	24	for	for	ADP
ajst-20185	146	25	improved	improved	ADJ
ajst-20185	146	26	brewing	brewing	NOUN
ajst-20185	146	27	efficiency	efficiency	NOUN
ajst-20185	146	28	and	and	CCONJ
ajst-20185	146	29	beer	beer	NOUN
ajst-20185	146	30	quality[j	quality[j	PROPN
ajst-20185	146	31	]	]	PUNCT
ajst-20185	146	32	.	.	PUNCT
ajst-20185	147	1	annual	annual	ADJ
ajst-20185	147	2	review	review	NOUN
ajst-20185	147	3	of	of	ADP
ajst-20185	147	4	food	food	NOUN
ajst-20185	147	5	science	science	NOUN
ajst-20185	147	6	and	and	CCONJ
ajst-20185	147	7	technology	technology	NOUN
ajst-20185	147	8	,	,	PUNCT
ajst-20185	147	9	2020	2020	NUM
ajst-20185	147	10	,	,	PUNCT
ajst-20185	147	11	11(1	11(1	NUM
ajst-20185	147	12	)	)	PUNCT
ajst-20185	147	13	.	.	PUNCT
ajst-20185	148	1	[	[	X
ajst-20185	148	2	9	9	NUM
ajst-20185	148	3	]	]	X
ajst-20185	148	4	bachmann	bachmann	PROPN
ajst-20185	148	5	h	h	PROPN
ajst-20185	148	6	,	,	PUNCT
ajst-20185	148	7	pronk	pronk	PROPN
ajst-20185	148	8	j	j	PROPN
ajst-20185	148	9	t	t	PROPN
ajst-20185	148	10	,	,	PUNCT
ajst-20185	148	11	kleerebezem	kleerebezem	NOUN
ajst-20185	148	12	m	m	PROPN
ajst-20185	148	13	,	,	PUNCT
ajst-20185	148	14	et	et	PROPN
ajst-20185	148	15	al	al	PROPN
ajst-20185	148	16	.	.	PROPN
ajst-20185	148	17	evolutionary	evolutionary	ADJ
ajst-20185	148	18	engineering	engineering	NOUN
ajst-20185	148	19	to	to	PART
ajst-20185	148	20	enhance	enhance	VERB
ajst-20185	148	21	starter	starter	ADJ
ajst-20185	148	22	culture	culture	NOUN
ajst-20185	148	23	performance	performance	NOUN
ajst-20185	148	24	in	in	ADP
ajst-20185	148	25	food	food	NOUN
ajst-20185	148	26	fermentations[j	fermentations[j	PROPN
ajst-20185	148	27	]	]	PUNCT
ajst-20185	148	28	.	.	PUNCT
ajst-20185	149	1	current	current	ADJ
ajst-20185	149	2	opinion	opinion	NOUN
ajst-20185	149	3	in	in	ADP
ajst-20185	149	4	biotechnology	biotechnology	NOUN
ajst-20185	149	5	,	,	PUNCT
ajst-20185	149	6	2015	2015	NUM
ajst-20185	149	7	,	,	PUNCT
ajst-20185	149	8	32	32	NUM
ajst-20185	149	9	.	.	PUNCT
ajst-20185	150	1	[	[	X
ajst-20185	150	2	10	10	NUM
ajst-20185	150	3	]	]	X
ajst-20185	150	4	royce	royce	PROPN
ajst-20185	150	5	l	l	PROPN
ajst-20185	150	6	a	a	PROPN
ajst-20185	150	7	,	,	PUNCT
ajst-20185	150	8	yoon	yoon	PROPN
ajst-20185	150	9	j	j	PROPN
ajst-20185	150	10	m	m	PROPN
ajst-20185	150	11	,	,	PUNCT
ajst-20185	150	12	chen	chen	PROPN
ajst-20185	150	13	y	y	PROPN
ajst-20185	150	14	,	,	PUNCT
ajst-20185	150	15	et	et	PROPN
ajst-20185	150	16	al	al	PROPN
ajst-20185	150	17	.	.	PROPN
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ajst-20185	150	19	for	for	ADP
ajst-20185	150	20	exogenous	exogenous	ADJ
ajst-20185	150	21	octanoic	octanoic	ADJ
ajst-20185	150	22	acid	acid	NOUN
ajst-20185	150	23	tolerance	tolerance	NOUN
ajst-20185	150	24	improves	improve	VERB
ajst-20185	150	25	carboxylic	carboxylic	ADJ
ajst-20185	150	26	acid	acid	NOUN
ajst-20185	150	27	production	production	NOUN
ajst-20185	150	28	and	and	CCONJ
ajst-20185	150	29	membrane	membrane	NOUN
ajst-20185	150	30	integrity[j	integrity[j	NOUN
ajst-20185	150	31	]	]	PUNCT
ajst-20185	150	32	.	.	PUNCT
ajst-20185	151	1	metabolic	metabolic	PROPN
ajst-20185	151	2	engineering	engineering	NOUN
ajst-20185	151	3	,	,	PUNCT
ajst-20185	151	4	2015	2015	NUM
ajst-20185	151	5	,	,	PUNCT
ajst-20185	151	6	29	29	NUM
ajst-20185	151	7	:	:	SYM
ajst-20185	151	8	180	180	NUM
ajst-20185	151	9	-	-	SYM
ajst-20185	151	10	188	188	NUM
ajst-20185	151	11	.	.	PUNCT
ajst-20185	152	1	[	[	X
ajst-20185	152	2	11	11	NUM
ajst-20185	152	3	]	]	X
ajst-20185	152	4	r	r	NOUN
ajst-20185	152	5	d	d	PROPN
ajst-20185	152	6	,	,	PUNCT
ajst-20185	152	7	r	r	NOUN
ajst-20185	152	8	s	s	PROPN
ajst-20185	152	9	,	,	PUNCT
ajst-20185	152	10	c	c	PROPN
ajst-20185	152	11	w	w	PROPN
ajst-20185	152	12	,	,	PUNCT
ajst-20185	152	13	et	et	PROPN
ajst-20185	152	14	al	al	PROPN
ajst-20185	152	15	.	.	PUNCT
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ajst-20185	152	17	of	of	ADP
ajst-20185	152	18	saccharomyces	saccharomyce	NOUN
ajst-20185	152	19	cerevisiae	cerevisiae	NOUN
ajst-20185	152	20	to	to	PART
ajst-20185	152	21	saline	saline	VERB
ajst-20185	152	22	stress	stress	NOUN
ajst-20185	152	23	through	through	ADP
ajst-20185	152	24	laboratory	laboratory	NOUN
ajst-20185	152	25	evolution.[j	evolution.[j	PROPN
ajst-20185	152	26	]	]	PROPN
ajst-20185	152	27	.	.	PUNCT
ajst-20185	153	1	journal	journal	PROPN
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ajst-20185	153	4	biology	biology	NOUN
ajst-20185	153	5	,	,	PUNCT
ajst-20185	153	6	2011	2011	NUM
ajst-20185	153	7	,	,	PUNCT
ajst-20185	153	8	24(5	24(5	NUM
ajst-20185	153	9	)	)	PUNCT
ajst-20185	153	10	.	.	PUNCT
ajst-20185	154	1	[	[	X
ajst-20185	154	2	12	12	NUM
ajst-20185	154	3	]	]	X
ajst-20185	154	4	dhar	dhar	PROPN
ajst-20185	154	5	,	,	PUNCT
ajst-20185	154	6	sgesser	sgesser	NOUN
ajst-20185	154	7	,	,	PUNCT
ajst-20185	154	8	yuan	yuan	NOUN
ajst-20185	154	9	,	,	PUNCT
ajst-20185	154	10	et	et	PROPN
ajst-20185	154	11	al	al	PROPN
ajst-20185	154	12	.	.	PUNCT
ajst-20185	154	13	adaptation	adaptation	NOUN
ajst-20185	154	14	of	of	ADP
ajst-20185	154	15	saccharomyces	saccharomyce	NOUN
ajst-20185	154	16	cerevisiae	cerevisiae	NOUN
ajst-20185	154	17	to	to	PART
ajst-20185	154	18	saline	saline	VERB
ajst-20185	154	19	stress	stress	NOUN
ajst-20185	154	20	through	through	ADP
ajst-20185	154	21	laboratory	laboratory	NOUN
ajst-20185	154	22	evolution[j	evolution[j	PROPN
ajst-20185	154	23	]	]	PUNCT
ajst-20185	154	24	.	.	PUNCT
ajst-20185	155	1	[	[	X
ajst-20185	155	2	13	13	NUM
ajst-20185	155	3	]	]	PUNCT
ajst-20185	155	4	xu	xu	PROPN
ajst-20185	156	1	x	x	PROPN
ajst-20185	156	2	,	,	PUNCT
ajst-20185	156	3	williams	williams	PROPN
ajst-20185	156	4	t	t	PROPN
ajst-20185	156	5	c	c	PROPN
ajst-20185	156	6	,	,	PUNCT
ajst-20185	156	7	divne	divne	ADV
ajst-20185	156	8	c	c	NOUN
ajst-20185	156	9	,	,	PUNCT
ajst-20185	156	10	et	et	PROPN
ajst-20185	156	11	al	al	PROPN
ajst-20185	156	12	.	.	PROPN
ajst-20185	157	1	evolutionary	evolutionary	ADJ
ajst-20185	157	2	engineering	engineering	NOUN
ajst-20185	157	3	in	in	ADP
ajst-20185	157	4	saccharomyces	saccharomyce	NOUN
ajst-20185	157	5	cerevisiae	cerevisiae	NOUN
ajst-20185	157	6	reveals	reveal	VERB
ajst-20185	157	7	a	a	DET
ajst-20185	157	8	trk1	trk1	NOUN
ajst-20185	157	9	-	-	PUNCT
ajst-20185	157	10	dependent	dependent	ADJ
ajst-20185	157	11	potassium	potassium	NOUN
ajst-20185	157	12	influx	influx	NOUN
ajst-20185	157	13	mechanism	mechanism	NOUN
ajst-20185	157	14	for	for	ADP
ajst-20185	157	15	propionic	propionic	ADJ
ajst-20185	157	16	acid	acid	NOUN
ajst-20185	157	17	tolerance[j	tolerance[j	NOUN
ajst-20185	157	18	]	]	PUNCT
ajst-20185	157	19	.	.	PUNCT
ajst-20185	158	1	biotechnology	biotechnology	NOUN
ajst-20185	158	2	for	for	ADP
ajst-20185	158	3	biofuels	biofuel	NOUN
ajst-20185	158	4	,	,	PUNCT
ajst-20185	158	5	2019	2019	NUM
ajst-20185	158	6	,	,	PUNCT
ajst-20185	158	7	12(1	12(1	NUM
ajst-20185	158	8	)	)	PUNCT
ajst-20185	158	9	.	.	PUNCT