id	sid	tid	token	lemma	pos
ajst-20192	1	1	academic	academic	ADJ
ajst-20192	1	2	journal	journal	NOUN
ajst-20192	1	3	of	of	ADP
ajst-20192	1	4	science	science	NOUN
ajst-20192	1	5	and	and	CCONJ
ajst-20192	1	6	technology	technology	NOUN
ajst-20192	1	7	issn	issn	NOUN
ajst-20192	1	8	:	:	PUNCT
ajst-20192	1	9	2771	2771	NUM
ajst-20192	1	10	-	-	SYM
ajst-20192	1	11	3032	3032	NUM
ajst-20192	1	12	|	|	NOUN
ajst-20192	1	13	vol	vol	NOUN
ajst-20192	1	14	.	.	PROPN
ajst-20192	2	1	10	10	NUM
ajst-20192	2	2	,	,	PUNCT
ajst-20192	2	3	no	no	INTJ
ajst-20192	2	4	.	.	NOUN
ajst-20192	2	5	2	2	NUM
ajst-20192	2	6	,	,	PUNCT
ajst-20192	2	7	2024	2024	NUM
ajst-20192	2	8	87	87	NUM
ajst-20192	2	9	effects	effect	NOUN
ajst-20192	2	10	of	of	ADP
ajst-20192	2	11	c479w	c479w	PROPN
ajst-20192	2	12	mutation	mutation	NOUN
ajst-20192	2	13	on	on	ADP
ajst-20192	2	14	the	the	DET
ajst-20192	2	15	structure	structure	NOUN
ajst-20192	2	16	and	and	CCONJ
ajst-20192	2	17	function	function	NOUN
ajst-20192	2	18	of	of	ADP
ajst-20192	2	19	band	band	NOUN
ajst-20192	2	20	3	3	NUM
ajst-20192	2	21	protein	protein	NOUN
ajst-20192	2	22	haiying	haiye	VERB
ajst-20192	2	23	lv	lv	PROPN
ajst-20192	2	24	department	department	PROPN
ajst-20192	2	25	of	of	ADP
ajst-20192	2	26	physics	physics	PROPN
ajst-20192	2	27	,	,	PUNCT
ajst-20192	2	28	zhejiang	zhejiang	PROPN
ajst-20192	2	29	normal	normal	PROPN
ajst-20192	2	30	university	university	PROPN
ajst-20192	2	31	,	,	PUNCT
ajst-20192	2	32	jinhua	jinhua	PROPN
ajst-20192	2	33	321004	321004	NUM
ajst-20192	2	34	,	,	PUNCT
ajst-20192	2	35	china	china	PROPN
ajst-20192	2	36	abstract	abstract	NOUN
ajst-20192	2	37	:	:	PUNCT
ajst-20192	2	38	band	band	NOUN
ajst-20192	2	39	3	3	NUM
ajst-20192	2	40	,	,	PUNCT
ajst-20192	2	41	or	or	CCONJ
ajst-20192	2	42	anion	anion	NOUN
ajst-20192	2	43	exchanger	exchanger	NOUN
ajst-20192	2	44	1	1	NUM
ajst-20192	2	45	(	(	PUNCT
ajst-20192	2	46	ae1	ae1	PROPN
ajst-20192	2	47	)	)	PUNCT
ajst-20192	2	48	,	,	PUNCT
ajst-20192	2	49	is	be	AUX
ajst-20192	2	50	one	one	NUM
ajst-20192	2	51	of	of	ADP
ajst-20192	2	52	the	the	DET
ajst-20192	2	53	indispensable	indispensable	ADJ
ajst-20192	2	54	transmembrane	transmembrane	ADJ
ajst-20192	2	55	proteins	protein	NOUN
ajst-20192	2	56	involved	involve	VERB
ajst-20192	2	57	in	in	ADP
ajst-20192	2	58	effective	effective	ADJ
ajst-20192	2	59	respiratory	respiratory	ADJ
ajst-20192	2	60	processes	process	NOUN
ajst-20192	2	61	in	in	ADP
ajst-20192	2	62	the	the	DET
ajst-20192	2	63	human	human	ADJ
ajst-20192	2	64	body	body	NOUN
ajst-20192	2	65	,	,	PUNCT
ajst-20192	2	66	mainly	mainly	ADV
ajst-20192	2	67	responsible	responsible	ADJ
ajst-20192	2	68	for	for	ADP
ajst-20192	2	69	the	the	DET
ajst-20192	2	70	exchange	exchange	NOUN
ajst-20192	2	71	of	of	ADP
ajst-20192	2	72	bicarbonate	bicarbonate	NOUN
ajst-20192	2	73	and	and	CCONJ
ajst-20192	2	74	chloride	chloride	NOUN
ajst-20192	2	75	ions	ion	NOUN
ajst-20192	2	76	on	on	ADP
ajst-20192	2	77	the	the	DET
ajst-20192	2	78	plasma	plasma	NOUN
ajst-20192	2	79	membrane	membrane	NOUN
ajst-20192	2	80	of	of	ADP
ajst-20192	2	81	red	red	ADJ
ajst-20192	2	82	blood	blood	NOUN
ajst-20192	2	83	cells	cell	NOUN
ajst-20192	2	84	.	.	PUNCT
ajst-20192	3	1	however	however	ADV
ajst-20192	3	2	,	,	PUNCT
ajst-20192	3	3	the	the	DET
ajst-20192	3	4	effect	effect	NOUN
ajst-20192	3	5	of	of	ADP
ajst-20192	3	6	related	related	ADJ
ajst-20192	3	7	gene	gene	NOUN
ajst-20192	3	8	mutations	mutation	NOUN
ajst-20192	3	9	on	on	ADP
ajst-20192	3	10	band	band	NOUN
ajst-20192	3	11	3	3	NUM
ajst-20192	3	12	ion	ion	NOUN
ajst-20192	3	13	transport	transport	NOUN
ajst-20192	3	14	is	be	AUX
ajst-20192	3	15	not	not	PART
ajst-20192	3	16	fully	fully	ADV
ajst-20192	3	17	understood	understand	VERB
ajst-20192	3	18	.	.	PUNCT
ajst-20192	4	1	in	in	ADP
ajst-20192	4	2	this	this	DET
ajst-20192	4	3	work	work	NOUN
ajst-20192	4	4	,	,	PUNCT
ajst-20192	4	5	we	we	PRON
ajst-20192	4	6	used	use	VERB
ajst-20192	4	7	all	all	DET
ajst-20192	4	8	-	-	PUNCT
ajst-20192	4	9	atom	atom	NOUN
ajst-20192	4	10	molecular	molecular	ADJ
ajst-20192	4	11	dynamics	dynamic	NOUN
ajst-20192	4	12	(	(	PUNCT
ajst-20192	4	13	md	md	NOUN
ajst-20192	4	14	)	)	PUNCT
ajst-20192	4	15	simulations	simulation	NOUN
ajst-20192	4	16	to	to	PART
ajst-20192	4	17	systematically	systematically	ADV
ajst-20192	4	18	investigate	investigate	VERB
ajst-20192	4	19	the	the	DET
ajst-20192	4	20	effects	effect	NOUN
ajst-20192	4	21	of	of	ADP
ajst-20192	4	22	the	the	DET
ajst-20192	4	23	mutation	mutation	NOUN
ajst-20192	4	24	from	from	ADP
ajst-20192	4	25	cysteine	cysteine	NOUN
ajst-20192	4	26	(	(	PUNCT
ajst-20192	4	27	c	c	NOUN
ajst-20192	4	28	)	)	PUNCT
ajst-20192	4	29	to	to	PART
ajst-20192	4	30	tryptophan	tryptophan	NOUN
ajst-20192	4	31	(	(	PUNCT
ajst-20192	4	32	w	w	NOUN
ajst-20192	4	33	)	)	PUNCT
ajst-20192	4	34	at	at	ADP
ajst-20192	4	35	site	site	NOUN
ajst-20192	4	36	479	479	NUM
ajst-20192	4	37	in	in	ADP
ajst-20192	4	38	band	band	NOUN
ajst-20192	4	39	3	3	NUM
ajst-20192	4	40	on	on	ADP
ajst-20192	4	41	the	the	DET
ajst-20192	4	42	structure	structure	NOUN
ajst-20192	4	43	of	of	ADP
ajst-20192	4	44	band	band	NOUN
ajst-20192	4	45	3	3	NUM
ajst-20192	4	46	and	and	CCONJ
ajst-20192	4	47	its	its	PRON
ajst-20192	4	48	interaction	interaction	NOUN
ajst-20192	4	49	with	with	ADP
ajst-20192	4	50	anions	anion	NOUN
ajst-20192	4	51	.	.	PUNCT
ajst-20192	5	1	we	we	PRON
ajst-20192	5	2	studied	study	VERB
ajst-20192	5	3	the	the	DET
ajst-20192	5	4	kinetics	kinetic	NOUN
ajst-20192	5	5	of	of	ADP
ajst-20192	5	6	wild	wild	ADJ
ajst-20192	5	7	-	-	PUNCT
ajst-20192	5	8	type	type	NOUN
ajst-20192	5	9	(	(	PUNCT
ajst-20192	5	10	wt	wt	NOUN
ajst-20192	5	11	)	)	PUNCT
ajst-20192	5	12	and	and	CCONJ
ajst-20192	5	13	mutant	mutant	ADJ
ajst-20192	5	14	band	band	NOUN
ajst-20192	5	15	3	3	NUM
ajst-20192	5	16	interactions	interaction	NOUN
ajst-20192	5	17	with	with	ADP
ajst-20192	5	18	bicarbonate	bicarbonate	NOUN
ajst-20192	5	19	and	and	CCONJ
ajst-20192	5	20	chloride	chloride	NOUN
ajst-20192	5	21	ions	ion	NOUN
ajst-20192	5	22	on	on	ADP
ajst-20192	5	23	the	the	DET
ajst-20192	5	24	microsecond	microsecond	NOUN
ajst-20192	5	25	scale	scale	NOUN
ajst-20192	5	26	.	.	PUNCT
ajst-20192	6	1	the	the	DET
ajst-20192	6	2	results	result	NOUN
ajst-20192	6	3	showed	show	VERB
ajst-20192	6	4	that	that	SCONJ
ajst-20192	6	5	the	the	DET
ajst-20192	6	6	mutation	mutation	NOUN
ajst-20192	6	7	at	at	ADP
ajst-20192	6	8	site	site	NOUN
ajst-20192	6	9	479	479	NUM
ajst-20192	6	10	affected	affect	VERB
ajst-20192	6	11	the	the	DET
ajst-20192	6	12	stability	stability	NOUN
ajst-20192	6	13	of	of	ADP
ajst-20192	6	14	band	band	NOUN
ajst-20192	6	15	3	3	NUM
ajst-20192	6	16	structure	structure	NOUN
ajst-20192	6	17	and	and	CCONJ
ajst-20192	6	18	the	the	DET
ajst-20192	6	19	distribution	distribution	NOUN
ajst-20192	6	20	of	of	ADP
ajst-20192	6	21	anions	anion	NOUN
ajst-20192	6	22	,	,	PUNCT
ajst-20192	6	23	and	and	CCONJ
ajst-20192	6	24	changed	change	VERB
ajst-20192	6	25	the	the	DET
ajst-20192	6	26	affinity	affinity	NOUN
ajst-20192	6	27	of	of	ADP
ajst-20192	6	28	anions	anion	NOUN
ajst-20192	6	29	to	to	ADP
ajst-20192	6	30	different	different	ADJ
ajst-20192	6	31	parts	part	NOUN
ajst-20192	6	32	of	of	ADP
ajst-20192	6	33	band	band	NOUN
ajst-20192	6	34	3	3	NUM
ajst-20192	6	35	.	.	PUNCT
ajst-20192	7	1	these	these	DET
ajst-20192	7	2	findings	finding	NOUN
ajst-20192	7	3	provide	provide	VERB
ajst-20192	7	4	some	some	DET
ajst-20192	7	5	insights	insight	NOUN
ajst-20192	7	6	into	into	ADP
ajst-20192	7	7	the	the	DET
ajst-20192	7	8	structural	structural	ADJ
ajst-20192	7	9	and	and	CCONJ
ajst-20192	7	10	functional	functional	ADJ
ajst-20192	7	11	effects	effect	NOUN
ajst-20192	7	12	of	of	ADP
ajst-20192	7	13	gene	gene	NOUN
ajst-20192	7	14	mutations	mutation	NOUN
ajst-20192	7	15	in	in	ADP
ajst-20192	7	16	band	band	NOUN
ajst-20192	7	17	3	3	NUM
ajst-20192	7	18	and	and	CCONJ
ajst-20192	7	19	contribute	contribute	VERB
ajst-20192	7	20	to	to	ADP
ajst-20192	7	21	understanding	understand	VERB
ajst-20192	7	22	band	band	NOUN
ajst-20192	7	23	3	3	NUM
ajst-20192	7	24	anion	anion	NOUN
ajst-20192	7	25	exchange	exchange	NOUN
ajst-20192	7	26	.	.	PUNCT
ajst-20192	8	1	keywords	keyword	NOUN
ajst-20192	8	2	:	:	PUNCT
ajst-20192	8	3	band	band	NOUN
ajst-20192	8	4	3	3	NUM
ajst-20192	8	5	;	;	PUNCT
ajst-20192	8	6	bicarbonate	bicarbonate	NOUN
ajst-20192	8	7	ions	ion	NOUN
ajst-20192	8	8	;	;	PUNCT
ajst-20192	8	9	molecular	molecular	ADJ
ajst-20192	8	10	dynamic	dynamic	ADJ
ajst-20192	8	11	simulations	simulation	NOUN
ajst-20192	8	12	.	.	PUNCT
ajst-20192	9	1	1	1	X
ajst-20192	9	2	.	.	X
ajst-20192	9	3	introduction	introduction	NOUN
ajst-20192	9	4	band	band	NOUN
ajst-20192	9	5	3	3	NUM
ajst-20192	9	6	,	,	PUNCT
ajst-20192	9	7	or	or	CCONJ
ajst-20192	9	8	anion	anion	NOUN
ajst-20192	9	9	exchanger	exchanger	NOUN
ajst-20192	9	10	1	1	NUM
ajst-20192	9	11	(	(	PUNCT
ajst-20192	9	12	ae1	ae1	PROPN
ajst-20192	9	13	)	)	PUNCT
ajst-20192	9	14	,	,	PUNCT
ajst-20192	9	15	is	be	AUX
ajst-20192	9	16	one	one	NUM
ajst-20192	9	17	of	of	ADP
ajst-20192	9	18	the	the	DET
ajst-20192	9	19	primary	primary	ADJ
ajst-20192	9	20	glycoproteins	glycoprotein	NOUN
ajst-20192	9	21	located	locate	VERB
ajst-20192	9	22	on	on	ADP
ajst-20192	9	23	the	the	DET
ajst-20192	9	24	red	red	ADJ
ajst-20192	9	25	blood	blood	NOUN
ajst-20192	9	26	cell	cell	NOUN
ajst-20192	9	27	membrane	membrane	NOUN
ajst-20192	9	28	.	.	PUNCT
ajst-20192	10	1	its	its	PRON
ajst-20192	10	2	main	main	ADJ
ajst-20192	10	3	function	function	NOUN
ajst-20192	10	4	is	be	AUX
ajst-20192	10	5	to	to	PART
ajst-20192	10	6	facilitate	facilitate	VERB
ajst-20192	10	7	the	the	DET
ajst-20192	10	8	rapid	rapid	ADJ
ajst-20192	10	9	exchange	exchange	NOUN
ajst-20192	10	10	of	of	ADP
ajst-20192	10	11	bicarbonate	bicarbonate	NOUN
ajst-20192	10	12	and	and	CCONJ
ajst-20192	10	13	chloride	chloride	NOUN
ajst-20192	10	14	ions	ion	NOUN
ajst-20192	10	15	across	across	ADP
ajst-20192	10	16	the	the	DET
ajst-20192	10	17	membrane	membrane	NOUN
ajst-20192	10	18	.	.	PUNCT
ajst-20192	11	1	[	[	X
ajst-20192	11	2	1	1	NUM
ajst-20192	11	3	]	]	PUNCT
ajst-20192	11	4	band	band	NOUN
ajst-20192	11	5	3	3	NUM
ajst-20192	11	6	consists	consist	VERB
ajst-20192	11	7	of	of	ADP
ajst-20192	11	8	911	911	NUM
ajst-20192	11	9	amino	amino	ADJ
ajst-20192	11	10	acids	acid	NOUN
ajst-20192	11	11	and	and	CCONJ
ajst-20192	11	12	is	be	AUX
ajst-20192	11	13	divided	divide	VERB
ajst-20192	11	14	into	into	ADP
ajst-20192	11	15	two	two	NUM
ajst-20192	11	16	domains	domain	NOUN
ajst-20192	11	17	:	:	PUNCT
ajst-20192	11	18	the	the	DET
ajst-20192	11	19	cytoplasmic	cytoplasmic	ADJ
ajst-20192	11	20	domain	domain	NOUN
ajst-20192	11	21	(	(	PUNCT
ajst-20192	11	22	cdae1	cdae1	PROPN
ajst-20192	11	23	,	,	PUNCT
ajst-20192	11	24	residues	residue	VERB
ajst-20192	11	25	1	1	NUM
ajst-20192	11	26	-	-	SYM
ajst-20192	11	27	360	360	NUM
ajst-20192	11	28	)	)	PUNCT
ajst-20192	11	29	at	at	ADP
ajst-20192	11	30	the	the	DET
ajst-20192	11	31	n	n	CCONJ
ajst-20192	11	32	-	-	PUNCT
ajst-20192	11	33	terminus	terminus	NOUN
ajst-20192	11	34	and	and	CCONJ
ajst-20192	11	35	the	the	DET
ajst-20192	11	36	membrane	membrane	NOUN
ajst-20192	11	37	domain	domain	NOUN
ajst-20192	11	38	(	(	PUNCT
ajst-20192	11	39	mdae1	mdae1	PROPN
ajst-20192	11	40	,	,	PUNCT
ajst-20192	11	41	residues	residue	VERB
ajst-20192	11	42	361	361	NUM
ajst-20192	11	43	-	-	SYM
ajst-20192	11	44	911	911	NUM
ajst-20192	11	45	)	)	PUNCT
ajst-20192	11	46	at	at	ADP
ajst-20192	11	47	the	the	DET
ajst-20192	11	48	c	c	NOUN
ajst-20192	11	49	-	-	NOUN
ajst-20192	11	50	terminus	terminus	NOUN
ajst-20192	11	51	.	.	PUNCT
ajst-20192	12	1	[	[	X
ajst-20192	12	2	2	2	X
ajst-20192	12	3	]	]	PUNCT
ajst-20192	12	4	the	the	DET
ajst-20192	12	5	two	two	NUM
ajst-20192	12	6	structure	structure	NOUN
ajst-20192	12	7	domains	domain	NOUN
ajst-20192	12	8	are	be	AUX
ajst-20192	12	9	responsible	responsible	ADJ
ajst-20192	12	10	for	for	ADP
ajst-20192	12	11	interacting	interact	VERB
ajst-20192	12	12	with	with	ADP
ajst-20192	12	13	the	the	DET
ajst-20192	12	14	cytoskeleton	cytoskeleton	NOUN
ajst-20192	12	15	and	and	CCONJ
ajst-20192	12	16	ion	ion	NOUN
ajst-20192	12	17	transport	transport	NOUN
ajst-20192	12	18	,	,	PUNCT
ajst-20192	12	19	respectively	respectively	ADV
ajst-20192	12	20	.	.	PUNCT
ajst-20192	13	1	[	[	X
ajst-20192	13	2	3	3	X
ajst-20192	13	3	]	]	PUNCT
ajst-20192	13	4	the	the	DET
ajst-20192	13	5	mdae1	mdae1	PROPN
ajst-20192	13	6	typically	typically	ADV
ajst-20192	13	7	exists	exist	VERB
ajst-20192	13	8	as	as	ADP
ajst-20192	13	9	a	a	DET
ajst-20192	13	10	dimer	dimer	NOUN
ajst-20192	13	11	in	in	ADP
ajst-20192	13	12	the	the	DET
ajst-20192	13	13	human	human	ADJ
ajst-20192	13	14	body	body	NOUN
ajst-20192	13	15	,	,	PUNCT
ajst-20192	13	16	with	with	SCONJ
ajst-20192	13	17	each	each	DET
ajst-20192	13	18	subunit	subunit	NOUN
ajst-20192	13	19	independently	independently	ADV
ajst-20192	13	20	involved	involve	VERB
ajst-20192	13	21	in	in	ADP
ajst-20192	13	22	ion	ion	NOUN
ajst-20192	13	23	transport	transport	NOUN
ajst-20192	13	24	.	.	PUNCT
ajst-20192	14	1	each	each	DET
ajst-20192	14	2	monomer	monomer	NOUN
ajst-20192	14	3	contains	contain	VERB
ajst-20192	14	4	14	14	NUM
ajst-20192	14	5	transmembrane	transmembrane	NOUN
ajst-20192	14	6	(	(	PUNCT
ajst-20192	14	7	tm	tm	NOUN
ajst-20192	14	8	)	)	PUNCT
ajst-20192	14	9	helices	helix	NOUN
ajst-20192	14	10	arranged	arrange	VERB
ajst-20192	14	11	in	in	ADP
ajst-20192	14	12	two	two	NUM
ajst-20192	14	13	repeated	repeat	VERB
ajst-20192	14	14	topologies	topology	NOUN
ajst-20192	14	15	with	with	ADP
ajst-20192	14	16	similar	similar	ADJ
ajst-20192	14	17	folds	fold	NOUN
ajst-20192	14	18	.	.	PUNCT
ajst-20192	15	1	based	base	VERB
ajst-20192	15	2	on	on	ADP
ajst-20192	15	3	their	their	PRON
ajst-20192	15	4	functional	functional	ADJ
ajst-20192	15	5	features	feature	NOUN
ajst-20192	15	6	,	,	PUNCT
ajst-20192	15	7	mdae1	mdae1	PROPN
ajst-20192	15	8	is	be	AUX
ajst-20192	15	9	divided	divide	VERB
ajst-20192	15	10	into	into	ADP
ajst-20192	15	11	a	a	DET
ajst-20192	15	12	core	core	NOUN
ajst-20192	15	13	domain	domain	NOUN
ajst-20192	15	14	(	(	PUNCT
ajst-20192	15	15	tm1	tm1	NOUN
ajst-20192	15	16	-	-	PUNCT
ajst-20192	15	17	4	4	NUM
ajst-20192	15	18	,	,	PUNCT
ajst-20192	15	19	8	8	NUM
ajst-20192	15	20	-	-	SYM
ajst-20192	15	21	11	11	NUM
ajst-20192	15	22	)	)	PUNCT
ajst-20192	15	23	and	and	CCONJ
ajst-20192	15	24	a	a	DET
ajst-20192	15	25	gate	gate	NOUN
ajst-20192	15	26	domain	domain	NOUN
ajst-20192	15	27	(	(	PUNCT
ajst-20192	15	28	tm5	tm5	NOUN
ajst-20192	15	29	-	-	PUNCT
ajst-20192	15	30	7	7	NUM
ajst-20192	15	31	,	,	PUNCT
ajst-20192	15	32	12	12	NUM
ajst-20192	15	33	-	-	SYM
ajst-20192	15	34	14	14	NUM
ajst-20192	15	35	)	)	PUNCT
ajst-20192	15	36	.	.	PUNCT
ajst-20192	16	1	[	[	X
ajst-20192	16	2	4	4	X
ajst-20192	16	3	]	]	X
ajst-20192	16	4	the	the	DET
ajst-20192	16	5	movement	movement	NOUN
ajst-20192	16	6	of	of	ADP
ajst-20192	16	7	these	these	DET
ajst-20192	16	8	two	two	NUM
ajst-20192	16	9	domains	domain	NOUN
ajst-20192	16	10	provides	provide	VERB
ajst-20192	16	11	an	an	DET
ajst-20192	16	12	exchange	exchange	NOUN
ajst-20192	16	13	pathway	pathway	NOUN
ajst-20192	16	14	for	for	ADP
ajst-20192	16	15	bicarbonate	bicarbonate	NOUN
ajst-20192	16	16	and	and	CCONJ
ajst-20192	16	17	chloride	chloride	NOUN
ajst-20192	16	18	anions	anion	NOUN
ajst-20192	16	19	to	to	PART
ajst-20192	16	20	access	access	VERB
ajst-20192	16	21	the	the	DET
ajst-20192	16	22	central	central	ADJ
ajst-20192	16	23	binding	bind	VERB
ajst-20192	16	24	sites	site	NOUN
ajst-20192	16	25	.	.	PUNCT
ajst-20192	17	1	[	[	X
ajst-20192	17	2	5	5	NUM
ajst-20192	17	3	]	]	PUNCT
ajst-20192	17	4	studies	study	NOUN
ajst-20192	17	5	have	have	AUX
ajst-20192	17	6	shown	show	VERB
ajst-20192	17	7	that	that	SCONJ
ajst-20192	17	8	mutations	mutation	NOUN
ajst-20192	17	9	at	at	ADP
ajst-20192	17	10	specific	specific	ADJ
ajst-20192	17	11	sites	site	NOUN
ajst-20192	17	12	on	on	ADP
ajst-20192	17	13	band	band	NOUN
ajst-20192	17	14	3	3	NUM
ajst-20192	17	15	are	be	AUX
ajst-20192	17	16	associated	associate	VERB
ajst-20192	17	17	with	with	ADP
ajst-20192	17	18	a	a	DET
ajst-20192	17	19	number	number	NOUN
ajst-20192	17	20	of	of	ADP
ajst-20192	17	21	physiological	physiological	ADJ
ajst-20192	17	22	diseases	disease	NOUN
ajst-20192	17	23	.	.	PUNCT
ajst-20192	18	1	[	[	X
ajst-20192	18	2	6	6	NUM
ajst-20192	18	3	]	]	PUNCT
ajst-20192	18	4	for	for	ADP
ajst-20192	18	5	example	example	NOUN
ajst-20192	18	6	,	,	PUNCT
ajst-20192	18	7	hereditary	hereditary	ADJ
ajst-20192	18	8	stomatocytosis	stomatocytosis	NOUN
ajst-20192	18	9	(	(	PUNCT
ajst-20192	18	10	hs	hs	X
ajst-20192	18	11	)	)	PUNCT
ajst-20192	18	12	associated	associate	VERB
ajst-20192	18	13	with	with	ADP
ajst-20192	18	14	anemia	anemia	NOUN
ajst-20192	18	15	and	and	CCONJ
ajst-20192	18	16	distal	distal	ADJ
ajst-20192	18	17	renal	renal	ADJ
ajst-20192	18	18	tubular	tubular	ADJ
ajst-20192	18	19	(	(	PUNCT
ajst-20192	18	20	drta	drta	NOUN
ajst-20192	18	21	)	)	PUNCT
ajst-20192	18	22	acidosis	acidosi	NOUN
ajst-20192	18	23	are	be	AUX
ajst-20192	18	24	associated	associate	VERB
ajst-20192	18	25	with	with	ADP
ajst-20192	18	26	metabolic	metabolic	NOUN
ajst-20192	18	27	acidosis	acidosis	NOUN
ajst-20192	18	28	.	.	PUNCT
ajst-20192	19	1	[	[	X
ajst-20192	19	2	6	6	NUM
ajst-20192	19	3	,	,	PUNCT
ajst-20192	19	4	7	7	NUM
ajst-20192	19	5	]	]	PUNCT
ajst-20192	19	6	notably	notably	ADV
ajst-20192	19	7	,	,	PUNCT
ajst-20192	19	8	c479w	c479w	PROPN
ajst-20192	19	9	mutant	mutant	NOUN
ajst-20192	19	10	on	on	ADP
ajst-20192	19	11	tm3	tm3	NOUN
ajst-20192	19	12	adversely	adversely	ADV
ajst-20192	19	13	affects	affect	VERB
ajst-20192	19	14	band	band	NOUN
ajst-20192	19	15	3	3	NUM
ajst-20192	19	16	folding	folding	NOUN
ajst-20192	19	17	,	,	PUNCT
ajst-20192	19	18	potentially	potentially	ADV
ajst-20192	19	19	disrupting	disrupt	VERB
ajst-20192	19	20	the	the	DET
ajst-20192	19	21	packaging	packaging	NOUN
ajst-20192	19	22	and	and	CCONJ
ajst-20192	19	23	impinging	impinge	VERB
ajst-20192	19	24	on	on	ADP
ajst-20192	19	25	band	band	NOUN
ajst-20192	19	26	3	3	NUM
ajst-20192	19	27	normal	normal	ADJ
ajst-20192	19	28	function	function	NOUN
ajst-20192	19	29	.	.	PUNCT
ajst-20192	20	1	therefore	therefore	ADV
ajst-20192	20	2	,	,	PUNCT
ajst-20192	20	3	studying	study	VERB
ajst-20192	20	4	mutations	mutation	NOUN
ajst-20192	20	5	in	in	ADP
ajst-20192	20	6	band	band	NOUN
ajst-20192	20	7	3	3	NUM
ajst-20192	20	8	is	be	AUX
ajst-20192	20	9	crucial	crucial	ADJ
ajst-20192	20	10	for	for	ADP
ajst-20192	20	11	understanding	understand	VERB
ajst-20192	20	12	their	their	PRON
ajst-20192	20	13	biological	biological	ADJ
ajst-20192	20	14	significance	significance	NOUN
ajst-20192	20	15	and	and	CCONJ
ajst-20192	20	16	for	for	ADP
ajst-20192	20	17	the	the	DET
ajst-20192	20	18	prevention	prevention	NOUN
ajst-20192	20	19	and	and	CCONJ
ajst-20192	20	20	treatment	treatment	NOUN
ajst-20192	20	21	of	of	ADP
ajst-20192	20	22	related	related	ADJ
ajst-20192	20	23	diseases	disease	NOUN
ajst-20192	20	24	.	.	PUNCT
ajst-20192	21	1	in	in	ADP
ajst-20192	21	2	this	this	DET
ajst-20192	21	3	study	study	NOUN
ajst-20192	21	4	,	,	PUNCT
ajst-20192	21	5	we	we	PRON
ajst-20192	21	6	particularly	particularly	ADV
ajst-20192	21	7	focus	focus	VERB
ajst-20192	21	8	on	on	ADP
ajst-20192	21	9	the	the	DET
ajst-20192	21	10	mutation	mutation	NOUN
ajst-20192	21	11	of	of	ADP
ajst-20192	21	12	c479w	c479w	PROPN
ajst-20192	21	13	,	,	PUNCT
ajst-20192	21	14	exploring	explore	VERB
ajst-20192	21	15	the	the	DET
ajst-20192	21	16	specific	specific	ADJ
ajst-20192	21	17	effects	effect	NOUN
ajst-20192	21	18	of	of	ADP
ajst-20192	21	19	this	this	DET
ajst-20192	21	20	mutation	mutation	NOUN
ajst-20192	21	21	on	on	ADP
ajst-20192	21	22	band	band	NOUN
ajst-20192	21	23	3	3	NUM
ajst-20192	21	24	protein	protein	NOUN
ajst-20192	21	25	folding	folding	NOUN
ajst-20192	21	26	and	and	CCONJ
ajst-20192	21	27	ion	ion	NOUN
ajst-20192	21	28	transport	transport	NOUN
ajst-20192	21	29	and	and	CCONJ
ajst-20192	21	30	providing	provide	VERB
ajst-20192	21	31	some	some	DET
ajst-20192	21	32	insights	insight	NOUN
ajst-20192	21	33	into	into	ADP
ajst-20192	21	34	related	related	ADJ
ajst-20192	21	35	fields	field	NOUN
ajst-20192	21	36	.	.	PUNCT
ajst-20192	22	1	2	2	X
ajst-20192	22	2	.	.	NOUN
ajst-20192	22	3	models	model	NOUN
ajst-20192	22	4	and	and	CCONJ
ajst-20192	22	5	methods	method	NOUN
ajst-20192	22	6	2.1	2.1	NUM
ajst-20192	22	7	.	.	PUNCT
ajst-20192	23	1	system	system	NOUN
ajst-20192	23	2	setup	setup	NOUN
ajst-20192	23	3	in	in	ADP
ajst-20192	23	4	this	this	DET
ajst-20192	23	5	study	study	NOUN
ajst-20192	23	6	,	,	PUNCT
ajst-20192	23	7	we	we	PRON
ajst-20192	23	8	employed	employ	VERB
ajst-20192	23	9	band	band	NOUN
ajst-20192	23	10	3	3	NUM
ajst-20192	23	11	monomer	monomer	NOUN
ajst-20192	23	12	to	to	PART
ajst-20192	23	13	investigate	investigate	VERB
ajst-20192	23	14	the	the	DET
ajst-20192	23	15	impact	impact	NOUN
ajst-20192	23	16	of	of	ADP
ajst-20192	23	17	mutations	mutation	NOUN
ajst-20192	23	18	on	on	ADP
ajst-20192	23	19	the	the	DET
ajst-20192	23	20	structure	structure	NOUN
ajst-20192	23	21	and	and	CCONJ
ajst-20192	23	22	function	function	NOUN
ajst-20192	23	23	of	of	ADP
ajst-20192	23	24	band	band	NOUN
ajst-20192	23	25	3	3	X
ajst-20192	23	26	.	.	PUNCT
ajst-20192	24	1	we	we	PRON
ajst-20192	24	2	only	only	ADV
ajst-20192	24	3	considered	consider	VERB
ajst-20192	24	4	the	the	DET
ajst-20192	24	5	membrane	membrane	NOUN
ajst-20192	24	6	domain	domain	NOUN
ajst-20192	24	7	of	of	ADP
ajst-20192	24	8	band	band	NOUN
ajst-20192	24	9	3	3	NUM
ajst-20192	24	10	with	with	ADP
ajst-20192	24	11	pdb	pdb	PROPN
ajst-20192	24	12	:	:	PUNCT
ajst-20192	24	13	4yzf	4yzf	NOUN
ajst-20192	24	14	.	.	PUNCT
ajst-20192	25	1	[	[	X
ajst-20192	25	2	8	8	NUM
ajst-20192	25	3	]	]	PUNCT
ajst-20192	25	4	we	we	PRON
ajst-20192	25	5	considered	consider	VERB
ajst-20192	25	6	the	the	DET
ajst-20192	25	7	wild	wild	ADJ
ajst-20192	25	8	-	-	PUNCT
ajst-20192	25	9	type	type	NOUN
ajst-20192	25	10	and	and	CCONJ
ajst-20192	25	11	c479w	c479w	PROPN
ajst-20192	25	12	mutant	mutant	NOUN
ajst-20192	25	13	of	of	ADP
ajst-20192	25	14	band	band	NOUN
ajst-20192	25	15	3	3	NUM
ajst-20192	25	16	.	.	PUNCT
ajst-20192	26	1	both	both	CCONJ
ajst-20192	26	2	the	the	DET
ajst-20192	26	3	c479w	c479w	PROPN
ajst-20192	26	4	mutant	mutant	NOUN
ajst-20192	26	5	and	and	CCONJ
ajst-20192	26	6	wild	wild	ADJ
ajst-20192	26	7	-	-	PUNCT
ajst-20192	26	8	type	type	NOUN
ajst-20192	26	9	of	of	ADP
ajst-20192	26	10	band	band	NOUN
ajst-20192	26	11	3	3	NUM
ajst-20192	26	12	were	be	AUX
ajst-20192	26	13	embedded	embed	VERB
ajst-20192	26	14	in	in	ADP
ajst-20192	26	15	lipid	lipid	NOUN
ajst-20192	26	16	bilayers	bilayer	NOUN
ajst-20192	26	17	composed	compose	VERB
ajst-20192	26	18	of	of	ADP
ajst-20192	26	19	dipalmitoyl	dipalmitoyl	ADJ
ajst-20192	26	20	-	-	PUNCT
ajst-20192	26	21	phosphatidylcholine	phosphatidylcholine	NOUN
ajst-20192	26	22	(	(	PUNCT
ajst-20192	26	23	dppc	dppc	NOUN
ajst-20192	26	24	)	)	PUNCT
ajst-20192	26	25	.	.	PUNCT
ajst-20192	27	1	all	all	DET
ajst-20192	27	2	models	model	NOUN
ajst-20192	27	3	were	be	AUX
ajst-20192	27	4	represented	represent	VERB
ajst-20192	27	5	as	as	ADP
ajst-20192	27	6	all	all	DET
ajst-20192	27	7	-	-	PUNCT
ajst-20192	27	8	atom	atom	NOUN
ajst-20192	27	9	systems	system	NOUN
ajst-20192	27	10	and	and	CCONJ
ajst-20192	27	11	simulated	simulate	VERB
ajst-20192	27	12	using	use	VERB
ajst-20192	27	13	the	the	DET
ajst-20192	27	14	charmm36	charmm36	NOUN
ajst-20192	27	15	force	force	NOUN
ajst-20192	27	16	field	field	NOUN
ajst-20192	27	17	,	,	PUNCT
ajst-20192	27	18	with	with	ADP
ajst-20192	27	19	charmm36	charmm36	NOUN
ajst-20192	27	20	m	m	VERB
ajst-20192	27	21	for	for	ADP
ajst-20192	27	22	proteins	protein	NOUN
ajst-20192	27	23	,	,	PUNCT
ajst-20192	27	24	charmm36	charmm36	NOUN
ajst-20192	27	25	for	for	ADP
ajst-20192	27	26	lipids	lipid	NOUN
ajst-20192	27	27	,	,	PUNCT
ajst-20192	27	28	and	and	CCONJ
ajst-20192	27	29	tip3p	tip3p	X
ajst-20192	27	30	for	for	ADP
ajst-20192	27	31	water	water	NOUN
ajst-20192	27	32	.	.	PUNCT
ajst-20192	28	1	[	[	X
ajst-20192	28	2	9	9	NUM
ajst-20192	28	3	]	]	PUNCT
ajst-20192	28	4	the	the	DET
ajst-20192	28	5	web	web	NOUN
ajst-20192	28	6	-	-	PUNCT
ajst-20192	28	7	based	base	VERB
ajst-20192	28	8	charmm	charmm	NOUN
ajst-20192	28	9	-	-	PUNCT
ajst-20192	28	10	gui	gui	NOUN
ajst-20192	28	11	membrane	membrane	NOUN
ajst-20192	28	12	builder	builder	NOUN
ajst-20192	28	13	was	be	AUX
ajst-20192	28	14	used	use	VERB
ajst-20192	28	15	to	to	PART
ajst-20192	28	16	build	build	VERB
ajst-20192	28	17	the	the	DET
ajst-20192	28	18	ternary	ternary	ADJ
ajst-20192	28	19	lipid	lipid	NOUN
ajst-20192	28	20	bilayers	bilayer	NOUN
ajst-20192	28	21	with	with	ADP
ajst-20192	28	22	band	band	NOUN
ajst-20192	28	23	3	3	NUM
ajst-20192	28	24	.	.	PUNCT
ajst-20192	29	1	[	[	X
ajst-20192	29	2	10	10	NUM
ajst-20192	29	3	]	]	PUNCT
ajst-20192	29	4	the	the	DET
ajst-20192	29	5	lipid	lipid	NOUN
ajst-20192	29	6	bilayer	bilayer	NOUN
ajst-20192	29	7	was	be	AUX
ajst-20192	29	8	solvated	solvate	VERB
ajst-20192	29	9	with	with	ADP
ajst-20192	29	10	approximately	approximately	ADV
ajst-20192	29	11	22500	22500	NUM
ajst-20192	29	12	water	water	NOUN
ajst-20192	29	13	molecules	molecule	NOUN
ajst-20192	29	14	.	.	PUNCT
ajst-20192	30	1	to	to	PART
ajst-20192	30	2	mimic	mimic	VERB
ajst-20192	30	3	physiological	physiological	ADJ
ajst-20192	30	4	conditions	condition	NOUN
ajst-20192	30	5	,	,	PUNCT
ajst-20192	30	6	0.075	0.075	NUM
ajst-20192	30	7	m	m	NOUN
ajst-20192	30	8	nacl	nacl	NOUN
ajst-20192	30	9	and	and	CCONJ
ajst-20192	30	10	0.075	0.075	NUM
ajst-20192	30	11	m	m	PROPN
ajst-20192	30	12	nahco₃	nahco₃	NOUN
ajst-20192	30	13	were	be	AUX
ajst-20192	30	14	added	add	VERB
ajst-20192	30	15	to	to	ADP
ajst-20192	30	16	the	the	DET
ajst-20192	30	17	system	system	NOUN
ajst-20192	30	18	,	,	PUNCT
ajst-20192	30	19	along	along	ADP
ajst-20192	30	20	with	with	ADP
ajst-20192	30	21	extra	extra	ADJ
ajst-20192	30	22	sodium	sodium	NOUN
ajst-20192	30	23	ions	ion	NOUN
ajst-20192	30	24	to	to	PART
ajst-20192	30	25	neutralize	neutralize	VERB
ajst-20192	30	26	the	the	DET
ajst-20192	30	27	negative	negative	ADJ
ajst-20192	30	28	charge	charge	NOUN
ajst-20192	30	29	carried	carry	VERB
ajst-20192	30	30	by	by	ADP
ajst-20192	30	31	band	band	NOUN
ajst-20192	30	32	3	3	NUM
ajst-20192	30	33	.	.	PUNCT
ajst-20192	31	1	the	the	DET
ajst-20192	31	2	size	size	NOUN
ajst-20192	31	3	of	of	ADP
ajst-20192	31	4	the	the	DET
ajst-20192	31	5	simulation	simulation	NOUN
ajst-20192	31	6	box	box	PROPN
ajst-20192	31	7	is	be	AUX
ajst-20192	31	8	about	about	ADV
ajst-20192	31	9	10×10×11	10×10×11	NUM
ajst-20192	31	10	nm3	nm3	NOUN
ajst-20192	31	11	.	.	PUNCT
ajst-20192	32	1	2.2	2.2	NUM
ajst-20192	32	2	.	.	PUNCT
ajst-20192	33	1	simulation	simulation	NOUN
ajst-20192	33	2	details	detail	NOUN
ajst-20192	33	3	simulations	simulation	NOUN
ajst-20192	33	4	were	be	AUX
ajst-20192	33	5	conducted	conduct	VERB
ajst-20192	33	6	using	use	VERB
ajst-20192	33	7	the	the	DET
ajst-20192	33	8	gromacs	gromac	NOUN
ajst-20192	33	9	2021.4plumed-2.7.3	2021.4plumed-2.7.3	NUM
ajst-20192	33	10	software	software	NOUN
ajst-20192	33	11	package	package	NOUN
ajst-20192	33	12	with	with	ADP
ajst-20192	33	13	an	an	DET
ajst-20192	33	14	integration	integration	NOUN
ajst-20192	33	15	time	time	NOUN
ajst-20192	33	16	step	step	NOUN
ajst-20192	33	17	of	of	ADP
ajst-20192	33	18	2	2	NUM
ajst-20192	33	19	fs	fs	NOUN
ajst-20192	33	20	.	.	PUNCT
ajst-20192	34	1	[	[	X
ajst-20192	34	2	11,12	11,12	NUM
ajst-20192	34	3	]	]	PUNCT
ajst-20192	34	4	constant	constant	ADJ
ajst-20192	34	5	particle	particle	NOUN
ajst-20192	34	6	number	number	NOUN
ajst-20192	34	7	,	,	PUNCT
ajst-20192	34	8	pressure	pressure	NOUN
ajst-20192	34	9	,	,	PUNCT
ajst-20192	34	10	and	and	CCONJ
ajst-20192	34	11	temperature	temperature	NOUN
ajst-20192	34	12	(	(	PUNCT
ajst-20192	34	13	npt	npt	NOUN
ajst-20192	34	14	)	)	PUNCT
ajst-20192	34	15	ensemble	ensemble	ADJ
ajst-20192	34	16	simulations	simulation	NOUN
ajst-20192	34	17	were	be	AUX
ajst-20192	34	18	employed	employ	VERB
ajst-20192	34	19	.	.	PUNCT
ajst-20192	35	1	the	the	DET
ajst-20192	35	2	system	system	NOUN
ajst-20192	35	3	temperature	temperature	NOUN
ajst-20192	35	4	was	be	AUX
ajst-20192	35	5	maintained	maintain	VERB
ajst-20192	35	6	at	at	ADP
ajst-20192	35	7	298	298	NUM
ajst-20192	35	8	k	k	NOUN
ajst-20192	35	9	using	use	VERB
ajst-20192	35	10	the	the	DET
ajst-20192	35	11	nother	nother	ADJ
ajst-20192	35	12	-	-	PUNCT
ajst-20192	35	13	hoover	hoover	NOUN
ajst-20192	35	14	thermostat	thermostat	NOUN
ajst-20192	35	15	with	with	ADP
ajst-20192	35	16	a	a	DET
ajst-20192	35	17	relaxation	relaxation	NOUN
ajst-20192	35	18	time	time	NOUN
ajst-20192	35	19	of	of	ADP
ajst-20192	35	20	1	1	NUM
ajst-20192	35	21	ps	ps	NOUN
ajst-20192	35	22	.	.	PUNCT
ajst-20192	36	1	[	[	X
ajst-20192	36	2	13	13	NUM
ajst-20192	36	3	]	]	PUNCT
ajst-20192	36	4	the	the	DET
ajst-20192	36	5	semi	semi	ADJ
ajst-20192	36	6	-	-	ADJ
ajst-20192	36	7	isotropic	isotropic	ADJ
ajst-20192	36	8	parrinello	parrinello	ADJ
ajst-20192	36	9	-	-	PUNCT
ajst-20192	36	10	rahman	rahman	NOUN
ajst-20192	36	11	barostat	barostat	NOUN
ajst-20192	36	12	,	,	PUNCT
ajst-20192	36	13	with	with	ADP
ajst-20192	36	14	relaxation	relaxation	NOUN
ajst-20192	36	15	times	time	NOUN
ajst-20192	36	16	of	of	ADP
ajst-20192	36	17	5	5	NUM
ajst-20192	36	18	ps	ps	NOUN
ajst-20192	36	19	,	,	PUNCT
ajst-20192	36	20	was	be	AUX
ajst-20192	36	21	used	use	VERB
ajst-20192	36	22	to	to	PART
ajst-20192	36	23	maintain	maintain	VERB
ajst-20192	36	24	the	the	DET
ajst-20192	36	25	pressure	pressure	NOUN
ajst-20192	36	26	at	at	ADP
ajst-20192	36	27	1.0	1.0	NUM
ajst-20192	36	28	bar	bar	NOUN
ajst-20192	36	29	separately	separately	ADV
ajst-20192	36	30	in	in	ADP
ajst-20192	36	31	the	the	DET
ajst-20192	36	32	membrane	membrane	NOUN
ajst-20192	36	33	plane	plane	NOUN
ajst-20192	36	34	(	(	PUNCT
ajst-20192	36	35	xy	xy	NOUN
ajst-20192	36	36	)	)	PUNCT
ajst-20192	36	37	and	and	CCONJ
ajst-20192	36	38	the	the	DET
ajst-20192	36	39	normal	normal	ADJ
ajst-20192	36	40	direction	direction	NOUN
ajst-20192	36	41	(	(	PUNCT
ajst-20192	36	42	z	z	NOUN
ajst-20192	36	43	)	)	PUNCT
ajst-20192	37	1	[	[	X
ajst-20192	37	2	14	14	NUM
ajst-20192	37	3	]	]	PUNCT
ajst-20192	37	4	.	.	PUNCT
ajst-20192	38	1	long	long	ADJ
ajst-20192	38	2	-	-	PUNCT
ajst-20192	38	3	range	range	NOUN
ajst-20192	38	4	electrostatic	electrostatic	ADJ
ajst-20192	38	5	interactions	interaction	NOUN
ajst-20192	38	6	were	be	AUX
ajst-20192	38	7	calculated	calculate	VERB
ajst-20192	38	8	using	use	VERB
ajst-20192	38	9	the	the	DET
ajst-20192	38	10	particle	particle	NOUN
ajst-20192	38	11	mesh	mesh	NOUN
ajst-20192	38	12	ewald	ewald	PROPN
ajst-20192	38	13	(	(	PUNCT
ajst-20192	38	14	pme	pme	PROPN
ajst-20192	38	15	)	)	PUNCT
ajst-20192	38	16	method	method	NOUN
ajst-20192	38	17	.	.	PUNCT
ajst-20192	39	1	[	[	X
ajst-20192	39	2	15	15	NUM
ajst-20192	39	3	]	]	PUNCT
ajst-20192	39	4	bond	bond	NOUN
ajst-20192	39	5	lengths	length	NOUN
ajst-20192	39	6	were	be	AUX
ajst-20192	39	7	constrained	constrain	VERB
ajst-20192	39	8	using	use	VERB
ajst-20192	39	9	the	the	DET
ajst-20192	39	10	lincs	lincs	NOUN
ajst-20192	39	11	algorithm	algorithm	NOUN
ajst-20192	39	12	.	.	PUNCT
ajst-20192	40	1	[	[	X
ajst-20192	40	2	16	16	NUM
ajst-20192	40	3	]	]	X
ajst-20192	40	4	periodic	periodic	ADJ
ajst-20192	40	5	boundary	boundary	ADJ
ajst-20192	40	6	conditions	condition	NOUN
ajst-20192	40	7	were	be	AUX
ajst-20192	40	8	applied	apply	VERB
ajst-20192	40	9	in	in	ADP
ajst-20192	40	10	all	all	DET
ajst-20192	40	11	three	three	NUM
ajst-20192	40	12	directions	direction	NOUN
ajst-20192	40	13	.	.	PUNCT
ajst-20192	41	1	each	each	DET
ajst-20192	41	2	system	system	NOUN
ajst-20192	41	3	was	be	AUX
ajst-20192	41	4	simulated	simulate	VERB
ajst-20192	41	5	for	for	ADP
ajst-20192	41	6	a	a	DET
ajst-20192	41	7	duration	duration	NOUN
ajst-20192	41	8	of	of	ADP
ajst-20192	41	9	250	250	NUM
ajst-20192	41	10	ns	ns	NUM
ajst-20192	41	11	.	.	PROPN
ajst-20192	41	12	2.3	2.3	NUM
ajst-20192	41	13	.	.	PUNCT
ajst-20192	42	1	data	datum	NOUN
ajst-20192	42	2	analysis	analysis	NOUN
ajst-20192	42	3	the	the	DET
ajst-20192	42	4	md	md	PROPN
ajst-20192	42	5	trajectory	trajectory	NOUN
ajst-20192	42	6	analysis	analysis	NOUN
ajst-20192	42	7	was	be	AUX
ajst-20192	42	8	primarily	primarily	ADV
ajst-20192	42	9	carried	carry	VERB
ajst-20192	42	10	out	out	ADP
ajst-20192	42	11	using	use	VERB
ajst-20192	42	12	tools	tool	NOUN
ajst-20192	42	13	from	from	ADP
ajst-20192	42	14	the	the	DET
ajst-20192	42	15	gromacs	gromacs	ADJ
ajst-20192	42	16	2021.4	2021.4	NUM
ajst-20192	42	17	-	-	PUNCT
ajst-20192	42	18	plumed-2.7.3	plumed-2.7.3	NOUN
ajst-20192	42	19	software	software	NOUN
ajst-20192	42	20	package	package	NOUN
ajst-20192	42	21	.	.	PUNCT
ajst-20192	43	1	visualization	visualization	NOUN
ajst-20192	43	2	of	of	ADP
ajst-20192	43	3	the	the	DET
ajst-20192	43	4	simulation	simulation	NOUN
ajst-20192	43	5	results	result	NOUN
ajst-20192	43	6	was	be	AUX
ajst-20192	43	7	achieved	achieve	VERB
ajst-20192	43	8	using	use	VERB
ajst-20192	43	9	visual	visual	ADJ
ajst-20192	43	10	molecular	molecular	ADJ
ajst-20192	43	11	dynamics	dynamic	NOUN
ajst-20192	43	12	(	(	PUNCT
ajst-20192	43	13	vmd	vmd	NOUN
ajst-20192	43	14	)	)	PUNCT
ajst-20192	43	15	software	software	NOUN
ajst-20192	43	16	.	.	PUNCT
ajst-20192	44	1	[	[	X
ajst-20192	44	2	17	17	NUM
ajst-20192	44	3	]	]	PUNCT
ajst-20192	44	4	the	the	DET
ajst-20192	44	5	number	number	NOUN
ajst-20192	44	6	of	of	ADP
ajst-20192	44	7	contacts	contact	NOUN
ajst-20192	44	8	between	between	ADP
ajst-20192	44	9	bicarbonate	bicarbonate	NOUN
ajst-20192	44	10	ions	ion	NOUN
ajst-20192	44	11	and	and	CCONJ
ajst-20192	44	12	band	band	NOUN
ajst-20192	44	13	3	3	NUM
ajst-20192	44	14	88	88	NUM
ajst-20192	44	15	residues	residue	NOUN
ajst-20192	44	16	was	be	AUX
ajst-20192	44	17	calculated	calculate	VERB
ajst-20192	44	18	using	use	VERB
ajst-20192	44	19	the	the	DET
ajst-20192	44	20	gmx	gmx	NOUN
ajst-20192	44	21	mindist	mindist	NOUN
ajst-20192	44	22	tool	tool	NOUN
ajst-20192	44	23	in	in	ADP
ajst-20192	44	24	gromacs	gromacs	NOUN
ajst-20192	44	25	,	,	PUNCT
ajst-20192	44	26	with	with	ADP
ajst-20192	44	27	a	a	DET
ajst-20192	44	28	cutoff	cutoff	NOUN
ajst-20192	44	29	distance	distance	NOUN
ajst-20192	44	30	of	of	ADP
ajst-20192	44	31	0.4	0.4	NUM
ajst-20192	44	32	nm	nm	NOUN
ajst-20192	44	33	.	.	PUNCT
ajst-20192	45	1	the	the	DET
ajst-20192	45	2	root	root	NOUN
ajst-20192	45	3	mean	mean	VERB
ajst-20192	45	4	square	square	ADJ
ajst-20192	45	5	deviation	deviation	NOUN
ajst-20192	45	6	(	(	PUNCT
ajst-20192	45	7	rmsd	rmsd	NOUN
ajst-20192	45	8	)	)	PUNCT
ajst-20192	45	9	of	of	ADP
ajst-20192	45	10	band	band	NOUN
ajst-20192	45	11	3	3	NUM
ajst-20192	45	12	was	be	AUX
ajst-20192	45	13	computed	compute	VERB
ajst-20192	45	14	using	use	VERB
ajst-20192	45	15	the	the	DET
ajst-20192	45	16	gmx	gmx	NOUN
ajst-20192	45	17	rms	rm	NOUN
ajst-20192	45	18	tool	tool	NOUN
ajst-20192	45	19	to	to	PART
ajst-20192	45	20	estimate	estimate	VERB
ajst-20192	45	21	its	its	PRON
ajst-20192	45	22	conformational	conformational	ADJ
ajst-20192	45	23	stability	stability	NOUN
ajst-20192	45	24	.	.	PUNCT
ajst-20192	46	1	the	the	DET
ajst-20192	46	2	distribution	distribution	NOUN
ajst-20192	46	3	of	of	ADP
ajst-20192	46	4	bicarbonate	bicarbonate	NOUN
ajst-20192	46	5	and	and	CCONJ
ajst-20192	46	6	chloride	chloride	NOUN
ajst-20192	46	7	ions	ion	NOUN
ajst-20192	46	8	was	be	AUX
ajst-20192	46	9	calculated	calculate	VERB
ajst-20192	46	10	using	use	VERB
ajst-20192	46	11	the	the	DET
ajst-20192	46	12	gmx	gmx	NOUN
ajst-20192	46	13	density	density	NOUN
ajst-20192	46	14	tool	tool	NOUN
ajst-20192	46	15	to	to	PART
ajst-20192	46	16	characterize	characterize	VERB
ajst-20192	46	17	the	the	DET
ajst-20192	46	18	interaction	interaction	NOUN
ajst-20192	46	19	between	between	ADP
ajst-20192	46	20	anions	anion	NOUN
ajst-20192	46	21	and	and	CCONJ
ajst-20192	46	22	band	band	NOUN
ajst-20192	46	23	3	3	NUM
ajst-20192	46	24	.	.	NOUN
ajst-20192	46	25	3	3	NUM
ajst-20192	46	26	.	.	NOUN
ajst-20192	46	27	results	result	NOUN
ajst-20192	46	28	and	and	CCONJ
ajst-20192	46	29	discussion	discussion	NOUN
ajst-20192	46	30	3.1	3.1	NUM
ajst-20192	46	31	.	.	PUNCT
ajst-20192	47	1	the	the	DET
ajst-20192	47	2	effect	effect	NOUN
ajst-20192	47	3	of	of	ADP
ajst-20192	47	4	c479w	c479w	PROPN
ajst-20192	47	5	mutation	mutation	NOUN
ajst-20192	47	6	on	on	ADP
ajst-20192	47	7	the	the	DET
ajst-20192	47	8	structure	structure	NOUN
ajst-20192	47	9	of	of	ADP
ajst-20192	47	10	band	band	NOUN
ajst-20192	47	11	3	3	NUM
ajst-20192	47	12	the	the	DET
ajst-20192	47	13	site	site	NOUN
ajst-20192	47	14	479	479	NUM
ajst-20192	47	15	is	be	AUX
ajst-20192	47	16	located	locate	VERB
ajst-20192	47	17	at	at	ADP
ajst-20192	47	18	tm3	tm3	NOUN
ajst-20192	47	19	,	,	PUNCT
ajst-20192	47	20	facing	face	VERB
ajst-20192	47	21	tm4	tm4	NOUN
ajst-20192	47	22	and	and	CCONJ
ajst-20192	47	23	tm8	tm8	NOUN
ajst-20192	47	24	.	.	PUNCT
ajst-20192	48	1	studies	study	NOUN
ajst-20192	48	2	have	have	AUX
ajst-20192	48	3	shown	show	VERB
ajst-20192	48	4	that	that	SCONJ
ajst-20192	48	5	c479w	c479w	PROPN
ajst-20192	48	6	mutation	mutation	NOUN
ajst-20192	48	7	may	may	AUX
ajst-20192	48	8	affect	affect	VERB
ajst-20192	48	9	protein	protein	NOUN
ajst-20192	48	10	folding	folding	NOUN
ajst-20192	48	11	.	.	PUNCT
ajst-20192	49	1	[	[	X
ajst-20192	49	2	18	18	NUM
ajst-20192	49	3	]	]	PUNCT
ajst-20192	49	4	as	as	SCONJ
ajst-20192	49	5	shown	show	VERB
ajst-20192	49	6	in	in	ADP
ajst-20192	49	7	figure	figure	NOUN
ajst-20192	49	8	1	1	NUM
ajst-20192	49	9	,	,	PUNCT
ajst-20192	49	10	we	we	PRON
ajst-20192	49	11	selected	select	VERB
ajst-20192	49	12	the	the	DET
ajst-20192	49	13	snapshots	snapshot	NOUN
ajst-20192	49	14	of	of	ADP
ajst-20192	49	15	the	the	DET
ajst-20192	49	16	wild	wild	ADJ
ajst-20192	49	17	-	-	PUNCT
ajst-20192	49	18	type	type	NOUN
ajst-20192	49	19	and	and	CCONJ
ajst-20192	49	20	c479w	c479w	PROPN
ajst-20192	49	21	mutant	mutant	NOUN
ajst-20192	49	22	at	at	ADP
ajst-20192	49	23	the	the	DET
ajst-20192	49	24	beginning	beginning	NOUN
ajst-20192	49	25	and	and	CCONJ
ajst-20192	49	26	end	end	NOUN
ajst-20192	49	27	of	of	ADP
ajst-20192	49	28	the	the	DET
ajst-20192	49	29	simulation	simulation	NOUN
ajst-20192	49	30	.	.	PUNCT
ajst-20192	50	1	we	we	PRON
ajst-20192	50	2	can	can	AUX
ajst-20192	50	3	see	see	VERB
ajst-20192	50	4	that	that	SCONJ
ajst-20192	50	5	the	the	DET
ajst-20192	50	6	folding	fold	VERB
ajst-20192	50	7	degree	degree	NOUN
ajst-20192	50	8	of	of	ADP
ajst-20192	50	9	the	the	DET
ajst-20192	50	10	mutant	mutant	ADJ
ajst-20192	50	11	band	band	NOUN
ajst-20192	50	12	3	3	NUM
ajst-20192	50	13	is	be	AUX
ajst-20192	50	14	smaller	small	ADJ
ajst-20192	50	15	than	than	ADP
ajst-20192	50	16	that	that	PRON
ajst-20192	50	17	of	of	ADP
ajst-20192	50	18	the	the	DET
ajst-20192	50	19	wild	wild	ADJ
ajst-20192	50	20	type	type	NOUN
ajst-20192	50	21	,	,	PUNCT
ajst-20192	50	22	indicating	indicate	VERB
ajst-20192	50	23	that	that	SCONJ
ajst-20192	50	24	the	the	DET
ajst-20192	50	25	c479w	c479w	PROPN
ajst-20192	50	26	mutation	mutation	NOUN
ajst-20192	50	27	affects	affect	VERB
ajst-20192	50	28	protein	protein	NOUN
ajst-20192	50	29	folding	folding	NOUN
ajst-20192	50	30	.	.	PUNCT
ajst-20192	51	1	figure	figure	NOUN
ajst-20192	51	2	1	1	NUM
ajst-20192	51	3	.	.	PUNCT
ajst-20192	52	1	(	(	PUNCT
ajst-20192	52	2	a	a	PRON
ajst-20192	52	3	,	,	PUNCT
ajst-20192	52	4	b	b	NOUN
ajst-20192	52	5	)	)	PUNCT
ajst-20192	52	6	snapshots	snapshot	NOUN
ajst-20192	52	7	of	of	ADP
ajst-20192	52	8	the	the	DET
ajst-20192	52	9	beginning	beginning	NOUN
ajst-20192	52	10	and	and	CCONJ
ajst-20192	52	11	end	end	VERB
ajst-20192	52	12	states	state	NOUN
ajst-20192	52	13	of	of	ADP
ajst-20192	52	14	the	the	DET
ajst-20192	52	15	wild	wild	ADJ
ajst-20192	52	16	-	-	PUNCT
ajst-20192	52	17	type	type	NOUN
ajst-20192	52	18	band	band	NOUN
ajst-20192	52	19	3	3	NUM
ajst-20192	52	20	in	in	ADP
ajst-20192	52	21	the	the	DET
ajst-20192	52	22	simulation	simulation	NOUN
ajst-20192	52	23	.	.	PUNCT
ajst-20192	53	1	(	(	PUNCT
ajst-20192	53	2	c	c	X
ajst-20192	53	3	,	,	PUNCT
ajst-20192	53	4	d	d	NOUN
ajst-20192	53	5	)	)	PUNCT
ajst-20192	53	6	snapshots	snapshot	NOUN
ajst-20192	53	7	of	of	ADP
ajst-20192	53	8	the	the	DET
ajst-20192	53	9	beginning	beginning	NOUN
ajst-20192	53	10	and	and	CCONJ
ajst-20192	53	11	end	end	VERB
ajst-20192	53	12	states	state	NOUN
ajst-20192	53	13	of	of	ADP
ajst-20192	53	14	c479w	c479w	PROPN
ajst-20192	53	15	mutant	mutant	ADJ
ajst-20192	53	16	band	band	NOUN
ajst-20192	53	17	3	3	NUM
ajst-20192	53	18	in	in	ADP
ajst-20192	53	19	the	the	DET
ajst-20192	53	20	simulation	simulation	NOUN
ajst-20192	53	21	.	.	PUNCT
ajst-20192	54	1	residue	residue	NOUN
ajst-20192	54	2	479	479	NUM
ajst-20192	54	3	is	be	AUX
ajst-20192	54	4	specifically	specifically	ADV
ajst-20192	54	5	labeled	label	VERB
ajst-20192	54	6	in	in	ADP
ajst-20192	54	7	green	green	ADJ
ajst-20192	54	8	.	.	PUNCT
ajst-20192	55	1	to	to	PART
ajst-20192	55	2	further	far	ADV
ajst-20192	55	3	quantify	quantify	VERB
ajst-20192	55	4	the	the	DET
ajst-20192	55	5	effect	effect	NOUN
ajst-20192	55	6	of	of	ADP
ajst-20192	55	7	this	this	DET
ajst-20192	55	8	site	site	NOUN
ajst-20192	55	9	mutation	mutation	NOUN
ajst-20192	55	10	on	on	ADP
ajst-20192	55	11	the	the	DET
ajst-20192	55	12	protein	protein	NOUN
ajst-20192	55	13	structure	structure	NOUN
ajst-20192	55	14	,	,	PUNCT
ajst-20192	55	15	we	we	PRON
ajst-20192	55	16	calculated	calculate	VERB
ajst-20192	55	17	the	the	DET
ajst-20192	55	18	root	root	NOUN
ajst-20192	55	19	mean	mean	ADJ
ajst-20192	55	20	square	square	ADJ
ajst-20192	55	21	deviation	deviation	NOUN
ajst-20192	55	22	(	(	PUNCT
ajst-20192	55	23	rmsd	rmsd	NOUN
ajst-20192	55	24	)	)	PUNCT
ajst-20192	55	25	of	of	ADP
ajst-20192	55	26	band	band	NOUN
ajst-20192	55	27	3	3	NUM
ajst-20192	55	28	during	during	ADP
ajst-20192	55	29	the	the	DET
ajst-20192	55	30	simulation	simulation	NOUN
ajst-20192	55	31	,	,	PUNCT
ajst-20192	55	32	as	as	SCONJ
ajst-20192	55	33	shown	show	VERB
ajst-20192	55	34	in	in	ADP
ajst-20192	55	35	the	the	DET
ajst-20192	55	36	figure	figure	NOUN
ajst-20192	55	37	2	2	NUM
ajst-20192	55	38	.	.	PUNCT
ajst-20192	56	1	the	the	DET
ajst-20192	56	2	rmsd	rmsd	NOUN
ajst-20192	56	3	of	of	ADP
ajst-20192	56	4	c479w	c479w	PROPN
ajst-20192	56	5	mutant	mutant	NOUN
ajst-20192	56	6	changed	change	VERB
ajst-20192	56	7	little	little	ADJ
ajst-20192	56	8	,	,	PUNCT
ajst-20192	56	9	which	which	PRON
ajst-20192	56	10	may	may	AUX
ajst-20192	56	11	have	have	AUX
ajst-20192	56	12	played	play	VERB
ajst-20192	56	13	a	a	DET
ajst-20192	56	14	certain	certain	ADJ
ajst-20192	56	15	role	role	NOUN
ajst-20192	56	16	in	in	ADP
ajst-20192	56	17	inhibiting	inhibit	VERB
ajst-20192	56	18	the	the	DET
ajst-20192	56	19	further	further	ADJ
ajst-20192	56	20	folding	folding	NOUN
ajst-20192	56	21	of	of	ADP
ajst-20192	56	22	band	band	NOUN
ajst-20192	56	23	3	3	NUM
ajst-20192	56	24	.	.	PUNCT
ajst-20192	56	25	figure	figure	NOUN
ajst-20192	56	26	2	2	NUM
ajst-20192	56	27	.	.	PUNCT
ajst-20192	56	28	root	root	NOUN
ajst-20192	56	29	-	-	PUNCT
ajst-20192	56	30	mean	mean	ADJ
ajst-20192	56	31	-	-	PUNCT
ajst-20192	56	32	square	square	NOUN
ajst-20192	56	33	deviation	deviation	NOUN
ajst-20192	56	34	(	(	PUNCT
ajst-20192	56	35	rmsd	rmsd	NOUN
ajst-20192	56	36	)	)	PUNCT
ajst-20192	56	37	of	of	ADP
ajst-20192	56	38	wild	wild	ADJ
ajst-20192	56	39	type	type	NOUN
ajst-20192	56	40	and	and	CCONJ
ajst-20192	56	41	c479w	c479w	PROPN
ajst-20192	56	42	mutant	mutant	NOUN
ajst-20192	56	43	as	as	ADP
ajst-20192	56	44	a	a	DET
ajst-20192	56	45	function	function	NOUN
ajst-20192	56	46	of	of	ADP
ajst-20192	56	47	simulation	simulation	NOUN
ajst-20192	56	48	time	time	NOUN
ajst-20192	56	49	.	.	PUNCT
ajst-20192	57	1	89	89	NUM
ajst-20192	57	2	3.2	3.2	NUM
ajst-20192	57	3	.	.	PUNCT
ajst-20192	58	1	the	the	DET
ajst-20192	58	2	effect	effect	NOUN
ajst-20192	58	3	of	of	ADP
ajst-20192	58	4	c479w	c479w	PROPN
ajst-20192	58	5	mutation	mutation	NOUN
ajst-20192	58	6	on	on	ADP
ajst-20192	58	7	the	the	DET
ajst-20192	58	8	function	function	NOUN
ajst-20192	58	9	of	of	ADP
ajst-20192	58	10	band	band	NOUN
ajst-20192	58	11	3	3	NUM
ajst-20192	58	12	it	it	PRON
ajst-20192	58	13	is	be	AUX
ajst-20192	58	14	well	well	ADV
ajst-20192	58	15	known	know	VERB
ajst-20192	58	16	that	that	SCONJ
ajst-20192	58	17	the	the	DET
ajst-20192	58	18	realization	realization	NOUN
ajst-20192	58	19	of	of	ADP
ajst-20192	58	20	transmembrane	transmembrane	ADJ
ajst-20192	58	21	protein	protein	NOUN
ajst-20192	58	22	function	function	NOUN
ajst-20192	58	23	is	be	AUX
ajst-20192	58	24	closely	closely	ADV
ajst-20192	58	25	related	relate	VERB
ajst-20192	58	26	to	to	ADP
ajst-20192	58	27	protein	protein	NOUN
ajst-20192	58	28	folding	folding	NOUN
ajst-20192	58	29	and	and	CCONJ
ajst-20192	58	30	conformation	conformation	NOUN
ajst-20192	58	31	.	.	PUNCT
ajst-20192	59	1	in	in	ADP
ajst-20192	59	2	the	the	DET
ajst-20192	59	3	last	last	ADJ
ajst-20192	59	4	part	part	NOUN
ajst-20192	59	5	of	of	ADP
ajst-20192	59	6	the	the	DET
ajst-20192	59	7	work	work	NOUN
ajst-20192	59	8	,	,	PUNCT
ajst-20192	59	9	we	we	PRON
ajst-20192	59	10	found	find	VERB
ajst-20192	59	11	that	that	SCONJ
ajst-20192	59	12	c479w	c479w	PROPN
ajst-20192	59	13	mutation	mutation	NOUN
ajst-20192	59	14	affect	affect	VERB
ajst-20192	59	15	the	the	DET
ajst-20192	59	16	conformation	conformation	NOUN
ajst-20192	59	17	of	of	ADP
ajst-20192	59	18	the	the	DET
ajst-20192	59	19	protein	protein	NOUN
ajst-20192	59	20	.	.	PUNCT
ajst-20192	60	1	in	in	ADP
ajst-20192	60	2	order	order	NOUN
ajst-20192	60	3	to	to	PART
ajst-20192	60	4	further	far	ADV
ajst-20192	60	5	explore	explore	VERB
ajst-20192	60	6	the	the	DET
ajst-20192	60	7	effect	effect	NOUN
ajst-20192	60	8	of	of	ADP
ajst-20192	60	9	mutation	mutation	NOUN
ajst-20192	60	10	on	on	ADP
ajst-20192	60	11	band	band	NOUN
ajst-20192	60	12	3	3	NUM
ajst-20192	60	13	function	function	NOUN
ajst-20192	60	14	,	,	PUNCT
ajst-20192	60	15	we	we	PRON
ajst-20192	60	16	calculated	calculate	VERB
ajst-20192	60	17	the	the	DET
ajst-20192	60	18	number	number	NOUN
ajst-20192	60	19	of	of	ADP
ajst-20192	60	20	bicarbonate	bicarbonate	NOUN
ajst-20192	60	21	ions	ion	NOUN
ajst-20192	60	22	and	and	CCONJ
ajst-20192	60	23	chloride	chloride	NOUN
ajst-20192	60	24	ions	ion	NOUN
ajst-20192	60	25	along	along	ADP
ajst-20192	60	26	z	z	NOUN
ajst-20192	60	27	direction	direction	NOUN
ajst-20192	60	28	for	for	ADP
ajst-20192	60	29	wild	wild	ADJ
ajst-20192	60	30	type	type	NOUN
ajst-20192	60	31	and	and	CCONJ
ajst-20192	60	32	c479w	c479w	PROPN
ajst-20192	60	33	mutant	mutant	NOUN
ajst-20192	60	34	.	.	PUNCT
ajst-20192	61	1	figure	figure	VERB
ajst-20192	61	2	3	3	NUM
ajst-20192	61	3	.	.	PUNCT
ajst-20192	62	1	the	the	DET
ajst-20192	62	2	number	number	NOUN
ajst-20192	62	3	of	of	ADP
ajst-20192	62	4	anions	anion	NOUN
ajst-20192	62	5	along	along	ADP
ajst-20192	62	6	z	z	NOUN
ajst-20192	62	7	direction	direction	NOUN
ajst-20192	62	8	.	.	PUNCT
ajst-20192	63	1	(	(	PUNCT
ajst-20192	63	2	a	a	X
ajst-20192	63	3	)	)	PUNCT
ajst-20192	63	4	the	the	DET
ajst-20192	63	5	number	number	NOUN
ajst-20192	63	6	of	of	ADP
ajst-20192	63	7	bicarbonate	bicarbonate	NOUN
ajst-20192	63	8	ions	ion	NOUN
ajst-20192	63	9	for	for	ADP
ajst-20192	63	10	wild	wild	ADJ
ajst-20192	63	11	type	type	NOUN
ajst-20192	63	12	and	and	CCONJ
ajst-20192	63	13	c479w	c479w	PROPN
ajst-20192	63	14	mutant	mutant	NOUN
ajst-20192	63	15	along	along	ADP
ajst-20192	63	16	the	the	DET
ajst-20192	63	17	z	z	NOUN
ajst-20192	63	18	direction	direction	NOUN
ajst-20192	63	19	.	.	PUNCT
ajst-20192	64	1	(	(	PUNCT
ajst-20192	64	2	b	b	X
ajst-20192	64	3	)	)	PUNCT
ajst-20192	64	4	the	the	DET
ajst-20192	64	5	number	number	NOUN
ajst-20192	64	6	of	of	ADP
ajst-20192	64	7	chloride	chloride	NOUN
ajst-20192	64	8	ions	ion	NOUN
ajst-20192	64	9	for	for	ADP
ajst-20192	64	10	wild	wild	ADJ
ajst-20192	64	11	type	type	NOUN
ajst-20192	64	12	and	and	CCONJ
ajst-20192	64	13	c479w	c479w	PROPN
ajst-20192	64	14	mutant	mutant	NOUN
ajst-20192	64	15	along	along	ADP
ajst-20192	64	16	the	the	DET
ajst-20192	64	17	z	z	NOUN
ajst-20192	64	18	direction	direction	NOUN
ajst-20192	64	19	.	.	PUNCT
ajst-20192	65	1	as	as	SCONJ
ajst-20192	65	2	shown	show	VERB
ajst-20192	65	3	in	in	ADP
ajst-20192	65	4	figure	figure	NOUN
ajst-20192	65	5	3	3	NUM
ajst-20192	65	6	,	,	PUNCT
ajst-20192	65	7	we	we	PRON
ajst-20192	65	8	found	find	VERB
ajst-20192	65	9	that	that	SCONJ
ajst-20192	65	10	the	the	DET
ajst-20192	65	11	number	number	NOUN
ajst-20192	65	12	of	of	ADP
ajst-20192	65	13	bicarbonate	bicarbonate	NOUN
ajst-20192	65	14	ions	ion	NOUN
ajst-20192	65	15	at	at	ADP
ajst-20192	65	16	2	2	NUM
ajst-20192	65	17	-	-	SYM
ajst-20192	65	18	4	4	NUM
ajst-20192	65	19	nm	nm	NOUN
ajst-20192	65	20	in	in	ADP
ajst-20192	65	21	wild	wild	ADJ
ajst-20192	65	22	type	type	NOUN
ajst-20192	65	23	band	band	NOUN
ajst-20192	65	24	3	3	NUM
ajst-20192	65	25	is	be	AUX
ajst-20192	65	26	lower	low	ADJ
ajst-20192	65	27	than	than	ADP
ajst-20192	65	28	that	that	PRON
ajst-20192	65	29	in	in	ADP
ajst-20192	65	30	c479w	c479w	PROPN
ajst-20192	65	31	mutant	mutant	NOUN
ajst-20192	65	32	.	.	PUNCT
ajst-20192	66	1	at	at	ADP
ajst-20192	66	2	5.8	5.8	NUM
ajst-20192	66	3	nm	nm	NOUN
ajst-20192	66	4	the	the	DET
ajst-20192	66	5	number	number	NOUN
ajst-20192	66	6	of	of	ADP
ajst-20192	66	7	mutant	mutant	ADJ
ajst-20192	66	8	ions	ion	NOUN
ajst-20192	66	9	increased	increase	VERB
ajst-20192	66	10	.	.	PUNCT
ajst-20192	67	1	it	it	PRON
ajst-20192	67	2	is	be	AUX
ajst-20192	67	3	clear	clear	ADJ
ajst-20192	67	4	that	that	SCONJ
ajst-20192	67	5	c479w	c479w	PROPN
ajst-20192	67	6	mutant	mutant	NOUN
ajst-20192	67	7	,	,	PUNCT
ajst-20192	67	8	a	a	DET
ajst-20192	67	9	portion	portion	NOUN
ajst-20192	67	10	of	of	ADP
ajst-20192	67	11	the	the	DET
ajst-20192	67	12	ions	ion	NOUN
ajst-20192	67	13	located	locate	VERB
ajst-20192	67	14	outside	outside	ADP
ajst-20192	67	15	the	the	DET
ajst-20192	67	16	membrane	membrane	NOUN
ajst-20192	67	17	plane	plane	NOUN
ajst-20192	67	18	are	be	AUX
ajst-20192	67	19	transferred	transfer	VERB
ajst-20192	67	20	to	to	ADP
ajst-20192	67	21	a	a	DET
ajst-20192	67	22	position	position	NOUN
ajst-20192	67	23	close	close	ADJ
ajst-20192	67	24	to	to	ADP
ajst-20192	67	25	the	the	DET
ajst-20192	67	26	membrane	membrane	NOUN
ajst-20192	67	27	surface	surface	NOUN
ajst-20192	67	28	.	.	PUNCT
ajst-20192	68	1	there	there	PRON
ajst-20192	68	2	was	be	VERB
ajst-20192	68	3	little	little	ADJ
ajst-20192	68	4	difference	difference	NOUN
ajst-20192	68	5	in	in	ADP
ajst-20192	68	6	the	the	DET
ajst-20192	68	7	distribution	distribution	NOUN
ajst-20192	68	8	of	of	ADP
ajst-20192	68	9	chloride	chloride	NOUN
ajst-20192	68	10	between	between	ADP
ajst-20192	68	11	the	the	DET
ajst-20192	68	12	wild	wild	ADJ
ajst-20192	68	13	type	type	NOUN
ajst-20192	68	14	and	and	CCONJ
ajst-20192	68	15	c479w	c479w	PROPN
ajst-20192	68	16	mutant	mutant	NOUN
ajst-20192	68	17	.	.	PUNCT
ajst-20192	69	1	figure	figure	VERB
ajst-20192	69	2	4	4	NUM
ajst-20192	69	3	.	.	PUNCT
ajst-20192	70	1	the	the	DET
ajst-20192	70	2	number	number	NOUN
ajst-20192	70	3	of	of	ADP
ajst-20192	70	4	contacts	contact	NOUN
ajst-20192	70	5	for	for	ADP
ajst-20192	70	6	(	(	PUNCT
ajst-20192	70	7	a	a	DET
ajst-20192	70	8	)	)	PUNCT
ajst-20192	70	9	wild	wild	ADJ
ajst-20192	70	10	type	type	NOUN
ajst-20192	70	11	and	and	CCONJ
ajst-20192	70	12	(	(	PUNCT
ajst-20192	70	13	b	b	NOUN
ajst-20192	70	14	)	)	PUNCT
ajst-20192	70	15	c479w	c479w	PROPN
ajst-20192	70	16	mutant	mutant	NOUN
ajst-20192	70	17	.	.	PUNCT
ajst-20192	71	1	we	we	PRON
ajst-20192	71	2	also	also	ADV
ajst-20192	71	3	calculated	calculate	VERB
ajst-20192	71	4	the	the	DET
ajst-20192	71	5	number	number	NOUN
ajst-20192	71	6	of	of	ADP
ajst-20192	71	7	contacts	contact	NOUN
ajst-20192	71	8	between	between	ADP
ajst-20192	71	9	bicarbonate	bicarbonate	NOUN
ajst-20192	71	10	ions	ion	NOUN
ajst-20192	71	11	and	and	CCONJ
ajst-20192	71	12	band	band	NOUN
ajst-20192	71	13	3	3	NUM
ajst-20192	71	14	for	for	ADP
ajst-20192	71	15	wild	wild	ADJ
ajst-20192	71	16	type	type	NOUN
ajst-20192	71	17	and	and	CCONJ
ajst-20192	71	18	c479w	c479w	PROPN
ajst-20192	71	19	mutants	mutant	NOUN
ajst-20192	71	20	.	.	PUNCT
ajst-20192	72	1	as	as	SCONJ
ajst-20192	72	2	shown	show	VERB
ajst-20192	72	3	in	in	ADP
ajst-20192	72	4	figure	figure	NOUN
ajst-20192	72	5	4	4	NUM
ajst-20192	72	6	,	,	PUNCT
ajst-20192	72	7	for	for	ADP
ajst-20192	72	8	the	the	DET
ajst-20192	72	9	wild	wild	ADJ
ajst-20192	72	10	type	type	NOUN
ajst-20192	72	11	,	,	PUNCT
ajst-20192	72	12	the	the	DET
ajst-20192	72	13	bicarbonate	bicarbonate	NOUN
ajst-20192	72	14	ions	ion	NOUN
ajst-20192	72	15	mainly	mainly	ADV
ajst-20192	72	16	contacts	contact	NOUN
ajst-20192	72	17	with	with	ADP
ajst-20192	72	18	residues	residue	NOUN
ajst-20192	72	19	near	near	ADP
ajst-20192	72	20	residue	residue	NOUN
ajst-20192	72	21	381	381	NUM
ajst-20192	72	22	and	and	CCONJ
ajst-20192	72	23	600	600	NUM
ajst-20192	72	24	;	;	PUNCT
ajst-20192	72	25	for	for	ADP
ajst-20192	72	26	c479w	c479w	PROPN
ajst-20192	72	27	mutant	mutant	NOUN
ajst-20192	72	28	,	,	PUNCT
ajst-20192	72	29	the	the	DET
ajst-20192	72	30	bicarbonate	bicarbonate	NOUN
ajst-20192	72	31	ions	ion	NOUN
ajst-20192	72	32	contacts	contact	NOUN
ajst-20192	72	33	with	with	ADP
ajst-20192	72	34	residues	residue	NOUN
ajst-20192	72	35	514	514	NUM
ajst-20192	72	36	and	and	CCONJ
ajst-20192	72	37	603	603	NUM
ajst-20192	72	38	more	more	ADV
ajst-20192	72	39	frequently	frequently	ADV
ajst-20192	72	40	.	.	PUNCT
ajst-20192	73	1	residue	residue	NOUN
ajst-20192	73	2	514	514	NUM
ajst-20192	73	3	is	be	AUX
ajst-20192	73	4	located	locate	VERB
ajst-20192	73	5	on	on	ADP
ajst-20192	73	6	the	the	DET
ajst-20192	73	7	amphiphilic	amphiphilic	ADJ
ajst-20192	73	8	helix	helix	NOUN
ajst-20192	73	9	and	and	CCONJ
ajst-20192	73	10	603	603	NUM
ajst-20192	73	11	is	be	AUX
ajst-20192	73	12	located	locate	VERB
ajst-20192	73	13	at	at	ADP
ajst-20192	73	14	the	the	DET
ajst-20192	73	15	end	end	NOUN
ajst-20192	73	16	of	of	ADP
ajst-20192	73	17	tm7	tm7	PROPN
ajst-20192	73	18	.	.	PUNCT
ajst-20192	74	1	both	both	PRON
ajst-20192	74	2	of	of	ADP
ajst-20192	74	3	these	these	DET
ajst-20192	74	4	residues	residue	NOUN
ajst-20192	74	5	are	be	AUX
ajst-20192	74	6	located	locate	VERB
ajst-20192	74	7	near	near	ADP
ajst-20192	74	8	the	the	DET
ajst-20192	74	9	cytoplasm	cytoplasm	NOUN
ajst-20192	74	10	.	.	PUNCT
ajst-20192	75	1	in	in	ADP
ajst-20192	75	2	other	other	ADJ
ajst-20192	75	3	words	word	NOUN
ajst-20192	75	4	,	,	PUNCT
ajst-20192	75	5	the	the	DET
ajst-20192	75	6	folding	folding	NOUN
ajst-20192	75	7	of	of	ADP
ajst-20192	75	8	c479w	c479w	PROPN
ajst-20192	75	9	mutant	mutant	NOUN
ajst-20192	75	10	may	may	AUX
ajst-20192	75	11	disturb	disturb	VERB
ajst-20192	75	12	the	the	DET
ajst-20192	75	13	structure	structure	NOUN
ajst-20192	75	14	of	of	ADP
ajst-20192	75	15	the	the	DET
ajst-20192	75	16	cytoplasmic	cytoplasmic	ADJ
ajst-20192	75	17	end	end	NOUN
ajst-20192	75	18	and	and	CCONJ
ajst-20192	75	19	change	change	VERB
ajst-20192	75	20	the	the	DET
ajst-20192	75	21	distribution	distribution	NOUN
ajst-20192	75	22	of	of	ADP
ajst-20192	75	23	ions	ion	NOUN
ajst-20192	75	24	on	on	ADP
ajst-20192	75	25	the	the	DET
ajst-20192	75	26	cytoplasmic	cytoplasmic	ADJ
ajst-20192	75	27	side	side	NOUN
ajst-20192	75	28	.	.	PUNCT
ajst-20192	76	1	4	4	X
ajst-20192	76	2	.	.	X
ajst-20192	76	3	conclusion	conclusion	NOUN
ajst-20192	76	4	in	in	ADP
ajst-20192	76	5	this	this	DET
ajst-20192	76	6	paper	paper	NOUN
ajst-20192	76	7	,	,	PUNCT
ajst-20192	76	8	using	use	VERB
ajst-20192	76	9	all	all	DET
ajst-20192	76	10	-	-	PUNCT
ajst-20192	76	11	atom	atom	NOUN
ajst-20192	76	12	molecular	molecular	ADJ
ajst-20192	76	13	dynamics	dynamic	NOUN
ajst-20192	76	14	simulations	simulation	NOUN
ajst-20192	76	15	,	,	PUNCT
ajst-20192	76	16	we	we	PRON
ajst-20192	76	17	study	study	VERB
ajst-20192	76	18	the	the	DET
ajst-20192	76	19	effects	effect	NOUN
ajst-20192	76	20	of	of	ADP
ajst-20192	76	21	c479w	c479w	PROPN
ajst-20192	76	22	mutation	mutation	NOUN
ajst-20192	76	23	on	on	ADP
ajst-20192	76	24	the	the	DET
ajst-20192	76	25	structure	structure	NOUN
ajst-20192	76	26	and	and	CCONJ
ajst-20192	76	27	function	function	NOUN
ajst-20192	76	28	of	of	ADP
ajst-20192	76	29	band	band	NOUN
ajst-20192	76	30	3	3	NUM
ajst-20192	76	31	.	.	PUNCT
ajst-20192	77	1	the	the	DET
ajst-20192	77	2	results	result	NOUN
ajst-20192	77	3	show	show	VERB
ajst-20192	77	4	that	that	SCONJ
ajst-20192	77	5	the	the	DET
ajst-20192	77	6	structural	structural	ADJ
ajst-20192	77	7	stability	stability	NOUN
ajst-20192	77	8	of	of	ADP
ajst-20192	77	9	band	band	NOUN
ajst-20192	77	10	3	3	NUM
ajst-20192	77	11	is	be	AUX
ajst-20192	77	12	affected	affect	VERB
ajst-20192	77	13	by	by	ADP
ajst-20192	77	14	the	the	DET
ajst-20192	77	15	c479w	c479w	PROPN
ajst-20192	77	16	mutant	mutant	NOUN
ajst-20192	77	17	.	.	PUNCT
ajst-20192	78	1	in	in	ADP
ajst-20192	78	2	addition	addition	NOUN
ajst-20192	78	3	,	,	PUNCT
ajst-20192	78	4	c479w	c479w	PROPN
ajst-20192	78	5	mutations	mutation	NOUN
ajst-20192	78	6	change	change	VERB
ajst-20192	78	7	the	the	DET
ajst-20192	78	8	distribution	distribution	NOUN
ajst-20192	78	9	of	of	ADP
ajst-20192	78	10	anions	anion	NOUN
ajst-20192	78	11	on	on	ADP
ajst-20192	78	12	band	band	NOUN
ajst-20192	78	13	3	3	NUM
ajst-20192	78	14	,	,	PUNCT
ajst-20192	78	15	which	which	PRON
ajst-20192	78	16	in	in	ADP
ajst-20192	78	17	turn	turn	NOUN
ajst-20192	78	18	affects	affect	VERB
ajst-20192	78	19	the	the	DET
ajst-20192	78	20	contacts	contact	NOUN
ajst-20192	78	21	between	between	ADP
ajst-20192	78	22	the	the	DET
ajst-20192	78	23	anion	anion	NOUN
ajst-20192	78	24	and	and	CCONJ
ajst-20192	78	25	band	band	NOUN
ajst-20192	78	26	3	3	NUM
ajst-20192	78	27	.	.	PUNCT
ajst-20192	79	1	these	these	DET
ajst-20192	79	2	findings	finding	NOUN
ajst-20192	79	3	provide	provide	VERB
ajst-20192	79	4	insights	insight	NOUN
ajst-20192	79	5	into	into	ADP
ajst-20192	79	6	the	the	DET
ajst-20192	79	7	effects	effect	NOUN
ajst-20192	79	8	of	of	ADP
ajst-20192	79	9	band	band	NOUN
ajst-20192	79	10	3	3	NUM
ajst-20192	79	11	related	relate	VERB
ajst-20192	79	12	gene	gene	NOUN
ajst-20192	79	13	mutations	mutation	NOUN
ajst-20192	79	14	on	on	ADP
ajst-20192	79	15	band	band	NOUN
ajst-20192	79	16	3	3	NUM
ajst-20192	79	17	structure	structure	NOUN
ajst-20192	79	18	and	and	CCONJ
ajst-20192	79	19	function	function	NOUN
ajst-20192	79	20	and	and	CCONJ
ajst-20192	79	21	may	may	AUX
ajst-20192	79	22	be	be	AUX
ajst-20192	79	23	helpful	helpful	ADJ
ajst-20192	79	24	to	to	PART
ajst-20192	79	25	understand	understand	VERB
ajst-20192	79	26	the	the	DET
ajst-20192	79	27	specific	specific	ADJ
ajst-20192	79	28	details	detail	NOUN
ajst-20192	79	29	of	of	ADP
ajst-20192	79	30	band	band	NOUN
ajst-20192	79	31	3	3	NUM
ajst-20192	79	32	conformational	conformational	ADJ
ajst-20192	79	33	transformation	transformation	NOUN
ajst-20192	79	34	.	.	PUNCT
ajst-20192	80	1	references	reference	NOUN
ajst-20192	80	2	[	[	X
ajst-20192	80	3	1	1	NUM
ajst-20192	80	4	]	]	X
ajst-20192	80	5	remigante	remigante	NOUN
ajst-20192	80	6	,	,	PUNCT
ajst-20192	80	7	a.	a.	NOUN
ajst-20192	80	8	;	;	PUNCT
ajst-20192	80	9	morabito	morabito	PROPN
ajst-20192	80	10	,	,	PUNCT
ajst-20192	80	11	r.	r.	PROPN
ajst-20192	80	12	;	;	PUNCT
ajst-20192	80	13	marino	marino	PROPN
ajst-20192	80	14	,	,	PUNCT
ajst-20192	80	15	a.	a.	NOUN
ajst-20192	80	16	band	band	NOUN
ajst-20192	80	17	3	3	NUM
ajst-20192	80	18	protein	protein	NOUN
ajst-20192	80	19	function	function	NOUN
ajst-20192	80	20	and	and	CCONJ
ajst-20192	80	21	oxidative	oxidative	ADJ
ajst-20192	80	22	stress	stress	NOUN
ajst-20192	80	23	in	in	ADP
ajst-20192	80	24	erythrocytes	erythrocyte	NOUN
ajst-20192	80	25	.	.	PUNCT
ajst-20192	81	1	j.	j.	PROPN
ajst-20192	81	2	cell	cell	PROPN
ajst-20192	81	3	.	.	PUNCT
ajst-20192	82	1	physiol	physiol	PROPN
ajst-20192	82	2	.	.	PUNCT
ajst-20192	83	1	2021	2021	NUM
ajst-20192	83	2	,	,	PUNCT
ajst-20192	83	3	236	236	NUM
ajst-20192	83	4	(	(	PUNCT
ajst-20192	83	5	9	9	NUM
ajst-20192	83	6	)	)	PUNCT
ajst-20192	83	7	,	,	PUNCT
ajst-20192	83	8	6225	6225	NUM
ajst-20192	83	9	-	-	SYM
ajst-20192	83	10	6234	6234	NUM
ajst-20192	83	11	.	.	PUNCT
ajst-20192	84	1	90	90	NUM
ajst-20192	85	1	[	[	SYM
ajst-20192	85	2	2	2	NUM
ajst-20192	85	3	]	]	SYM
ajst-20192	85	4	reithmeier	reithmeier	NOUN
ajst-20192	85	5	,	,	PUNCT
ajst-20192	85	6	r.	r.	PROPN
ajst-20192	85	7	a.	a.	PROPN
ajst-20192	85	8	f.	f.	PROPN
ajst-20192	85	9	;	;	PUNCT
ajst-20192	86	1	casey	casey	PROPN
ajst-20192	86	2	,	,	PUNCT
ajst-20192	86	3	j.	j.	PROPN
ajst-20192	86	4	r.	r.	PROPN
ajst-20192	86	5	;	;	PUNCT
ajst-20192	86	6	kalli	kalli	PROPN
ajst-20192	86	7	,	,	PUNCT
ajst-20192	86	8	a.	a.	PROPN
ajst-20192	86	9	c.	c.	PROPN
ajst-20192	86	10	;	;	PUNCT
ajst-20192	86	11	sansom	sansom	PROPN
ajst-20192	86	12	,	,	PUNCT
ajst-20192	86	13	m.	m.	NOUN
ajst-20192	86	14	s.	s.	PROPN
ajst-20192	86	15	p.	p.	PROPN
ajst-20192	86	16	;	;	PUNCT
ajst-20192	86	17	alguel	alguel	PROPN
ajst-20192	86	18	,	,	PUNCT
ajst-20192	86	19	y.	y.	PROPN
ajst-20192	86	20	;	;	PUNCT
ajst-20192	86	21	iwata	iwata	PROPN
ajst-20192	86	22	,	,	PUNCT
ajst-20192	86	23	s.	s.	PROPN
ajst-20192	86	24	band	band	PROPN
ajst-20192	86	25	3	3	NUM
ajst-20192	86	26	,	,	PUNCT
ajst-20192	86	27	the	the	DET
ajst-20192	86	28	human	human	ADJ
ajst-20192	86	29	red	red	ADJ
ajst-20192	86	30	cell	cell	NOUN
ajst-20192	86	31	chloride	chloride	NOUN
ajst-20192	86	32	/	/	SYM
ajst-20192	86	33	bicarbonate	bicarbonate	NOUN
ajst-20192	86	34	anion	anion	NOUN
ajst-20192	86	35	exchanger	exchanger	NOUN
ajst-20192	86	36	(	(	PUNCT
ajst-20192	86	37	ae1	ae1	PROPN
ajst-20192	86	38	,	,	PUNCT
ajst-20192	86	39	slc4a1	slc4a1	NOUN
ajst-20192	86	40	)	)	PUNCT
ajst-20192	86	41	,	,	PUNCT
ajst-20192	86	42	in	in	ADP
ajst-20192	86	43	a	a	DET
ajst-20192	86	44	structural	structural	ADJ
ajst-20192	86	45	context	context	NOUN
ajst-20192	86	46	.	.	PUNCT
ajst-20192	87	1	biochim	biochim	NOUN
ajst-20192	87	2	.	.	PUNCT
ajst-20192	88	1	biophys	biophy	NOUN
ajst-20192	88	2	.	.	PUNCT
ajst-20192	89	1	acta	acta	PROPN
ajst-20192	89	2	.	.	PUNCT
ajst-20192	90	1	2016	2016	NUM
ajst-20192	90	2	,	,	PUNCT
ajst-20192	90	3	1858	1858	NUM
ajst-20192	90	4	(	(	PUNCT
ajst-20192	90	5	7	7	NUM
ajst-20192	90	6	)	)	PUNCT
ajst-20192	90	7	,	,	PUNCT
ajst-20192	90	8	1507	1507	NUM
ajst-20192	90	9	-	-	SYM
ajst-20192	90	10	1532	1532	NUM
ajst-20192	90	11	.	.	PUNCT
ajst-20192	91	1	[	[	X
ajst-20192	91	2	3	3	NUM
ajst-20192	91	3	]	]	X
ajst-20192	91	4	jennings	jennings	PROPN
ajst-20192	91	5	,	,	PUNCT
ajst-20192	91	6	m.	m.	PROPN
ajst-20192	91	7	l.	l.	PROPN
ajst-20192	91	8	cell	cell	PROPN
ajst-20192	91	9	physiology	physiology	NOUN
ajst-20192	91	10	and	and	CCONJ
ajst-20192	91	11	molecular	molecular	ADJ
ajst-20192	91	12	mechanism	mechanism	NOUN
ajst-20192	91	13	of	of	ADP
ajst-20192	91	14	anion	anion	NOUN
ajst-20192	91	15	transport	transport	NOUN
ajst-20192	91	16	by	by	ADP
ajst-20192	91	17	erythrocyte	erythrocyte	ADJ
ajst-20192	91	18	band	band	NOUN
ajst-20192	91	19	3	3	NUM
ajst-20192	91	20	/	/	SYM
ajst-20192	91	21	ae1	ae1	PROPN
ajst-20192	91	22	.	.	PROPN
ajst-20192	91	23	am	be	AUX
ajst-20192	91	24	.	.	PUNCT
ajst-20192	92	1	j.	j.	PROPN
ajst-20192	92	2	physiol	physiol	PROPN
ajst-20192	92	3	.	.	PUNCT
ajst-20192	93	1	cell	cell	NOUN
ajst-20192	93	2	physiol	physiol	PROPN
ajst-20192	93	3	.	.	PUNCT
ajst-20192	94	1	2021	2021	NUM
ajst-20192	94	2	,	,	PUNCT
ajst-20192	94	3	321	321	NUM
ajst-20192	94	4	(	(	PUNCT
ajst-20192	94	5	6	6	NUM
ajst-20192	94	6	)	)	PUNCT
ajst-20192	94	7	,	,	PUNCT
ajst-20192	94	8	c1028	c1028	NOUN
ajst-20192	94	9	-	-	PUNCT
ajst-20192	94	10	c1059	c1059	NOUN
ajst-20192	94	11	.	.	PUNCT
ajst-20192	95	1	[	[	X
ajst-20192	95	2	4	4	NUM
ajst-20192	95	3	]	]	X
ajst-20192	95	4	kalli	kalli	PROPN
ajst-20192	95	5	,	,	PUNCT
ajst-20192	95	6	a.	a.	PROPN
ajst-20192	95	7	c.	c.	PROPN
ajst-20192	95	8	;	;	PUNCT
ajst-20192	95	9	reithmeier	reithmeier	PROPN
ajst-20192	95	10	,	,	PUNCT
ajst-20192	95	11	r.	r.	PROPN
ajst-20192	95	12	a.	a.	PROPN
ajst-20192	95	13	f.	f.	PROPN
ajst-20192	95	14	organization	organization	PROPN
ajst-20192	95	15	and	and	CCONJ
ajst-20192	95	16	dynamics	dynamic	NOUN
ajst-20192	95	17	of	of	ADP
ajst-20192	95	18	the	the	DET
ajst-20192	95	19	red	red	ADJ
ajst-20192	95	20	blood	blood	NOUN
ajst-20192	95	21	cell	cell	NOUN
ajst-20192	95	22	band	band	NOUN
ajst-20192	95	23	3	3	NUM
ajst-20192	95	24	anion	anion	NOUN
ajst-20192	95	25	exchanger	exchanger	NOUN
ajst-20192	95	26	slc4a1	slc4a1	NOUN
ajst-20192	95	27	:	:	PUNCT
ajst-20192	95	28	insights	insight	NOUN
ajst-20192	95	29	from	from	ADP
ajst-20192	95	30	molecular	molecular	ADJ
ajst-20192	95	31	dynamics	dynamic	NOUN
ajst-20192	95	32	simulations	simulation	NOUN
ajst-20192	95	33	.	.	PUNCT
ajst-20192	96	1	front	front	ADJ
ajst-20192	96	2	physiol	physiol	PROPN
ajst-20192	96	3	.	.	PUNCT
ajst-20192	97	1	2022	2022	NUM
ajst-20192	97	2	,	,	PUNCT
ajst-20192	97	3	13	13	NUM
ajst-20192	97	4	,	,	PUNCT
ajst-20192	97	5	817945	817945	NUM
ajst-20192	97	6	.	.	PUNCT
ajst-20192	98	1	[	[	X
ajst-20192	98	2	5	5	NUM
ajst-20192	98	3	]	]	SYM
ajst-20192	98	4	zhekova	zhekova	PROPN
ajst-20192	98	5	,	,	PUNCT
ajst-20192	98	6	h.	h.	PROPN
ajst-20192	98	7	r.	r.	PROPN
ajst-20192	98	8	;	;	PUNCT
ajst-20192	98	9	pushkin	pushkin	PROPN
ajst-20192	98	10	,	,	PUNCT
ajst-20192	98	11	a.	a.	NOUN
ajst-20192	98	12	;	;	PUNCT
ajst-20192	98	13	kayik	kayik	PROPN
ajst-20192	98	14	,	,	PUNCT
ajst-20192	98	15	g.	g.	PROPN
ajst-20192	98	16	;	;	PUNCT
ajst-20192	98	17	kao	kao	PROPN
ajst-20192	98	18	,	,	PUNCT
ajst-20192	98	19	l.	l.	PROPN
ajst-20192	98	20	;	;	PUNCT
ajst-20192	98	21	azimov	azimov	PROPN
ajst-20192	98	22	,	,	PUNCT
ajst-20192	98	23	r.	r.	PROPN
ajst-20192	98	24	;	;	PUNCT
ajst-20192	98	25	abuladze	abuladze	VERB
ajst-20192	98	26	,	,	PUNCT
ajst-20192	98	27	n.	n.	PROPN
ajst-20192	98	28	;	;	PUNCT
ajst-20192	98	29	kurtz	kurtz	PROPN
ajst-20192	98	30	,	,	PUNCT
ajst-20192	98	31	d.	d.	PROPN
ajst-20192	98	32	;	;	PUNCT
ajst-20192	98	33	damergi	damergi	PROPN
ajst-20192	98	34	,	,	PUNCT
ajst-20192	98	35	m.	m.	NOUN
ajst-20192	98	36	;	;	PUNCT
ajst-20192	98	37	noskov	noskov	PROPN
ajst-20192	98	38	,	,	PUNCT
ajst-20192	98	39	s.	s.	PROPN
ajst-20192	98	40	y.	y.	PROPN
ajst-20192	98	41	;	;	PUNCT
ajst-20192	98	42	kurtz	kurtz	PROPN
ajst-20192	98	43	,	,	PUNCT
ajst-20192	98	44	i.	i.	NOUN
ajst-20192	98	45	identification	identification	NOUN
ajst-20192	98	46	of	of	ADP
ajst-20192	98	47	multiple	multiple	ADJ
ajst-20192	98	48	substrate	substrate	NOUN
ajst-20192	98	49	binding	bind	VERB
ajst-20192	98	50	sites	site	NOUN
ajst-20192	98	51	in	in	ADP
ajst-20192	98	52	slc4	slc4	ADJ
ajst-20192	98	53	transporters	transporter	NOUN
ajst-20192	98	54	in	in	ADP
ajst-20192	98	55	the	the	DET
ajst-20192	98	56	outward	outward	ADV
ajst-20192	98	57	-	-	PUNCT
ajst-20192	98	58	facing	face	VERB
ajst-20192	98	59	conformation	conformation	NOUN
ajst-20192	98	60	:	:	PUNCT
ajst-20192	98	61	insights	insight	NOUN
ajst-20192	98	62	into	into	ADP
ajst-20192	98	63	the	the	DET
ajst-20192	98	64	transport	transport	NOUN
ajst-20192	98	65	mechanism	mechanism	NOUN
ajst-20192	98	66	.	.	PUNCT
ajst-20192	99	1	j.	j.	PROPN
ajst-20192	99	2	biol	biol	PROPN
ajst-20192	99	3	.	.	PUNCT
ajst-20192	100	1	chem	chem	PROPN
ajst-20192	100	2	.	.	PUNCT
ajst-20192	101	1	2021	2021	NUM
ajst-20192	101	2	,	,	PUNCT
ajst-20192	101	3	296	296	NUM
ajst-20192	101	4	,	,	PUNCT
ajst-20192	101	5	100724	100724	NUM
ajst-20192	101	6	.	.	PUNCT
ajst-20192	102	1	[	[	X
ajst-20192	102	2	6	6	NUM
ajst-20192	102	3	]	]	PUNCT
ajst-20192	102	4	narla	narla	PROPN
ajst-20192	102	5	,	,	PUNCT
ajst-20192	102	6	j.	j.	PROPN
ajst-20192	102	7	;	;	PUNCT
ajst-20192	102	8	mohandas	mohandas	PROPN
ajst-20192	102	9	,	,	PUNCT
ajst-20192	102	10	n.	n.	ADJ
ajst-20192	102	11	red	red	ADJ
ajst-20192	102	12	cell	cell	NOUN
ajst-20192	102	13	membrane	membrane	NOUN
ajst-20192	102	14	disorders	disorder	NOUN
ajst-20192	102	15	.	.	PUNCT
ajst-20192	103	1	int	int	NOUN
ajst-20192	103	2	.	.	PUNCT
ajst-20192	104	1	j.	j.	PROPN
ajst-20192	104	2	hematol	hematol	PROPN
ajst-20192	104	3	.	.	PUNCT
ajst-20192	105	1	2017	2017	NUM
ajst-20192	105	2	,	,	PUNCT
ajst-20192	105	3	39	39	NUM
ajst-20192	105	4	(	(	PUNCT
ajst-20192	105	5	s1	s1	NOUN
ajst-20192	105	6	)	)	PUNCT
ajst-20192	105	7	,	,	PUNCT
ajst-20192	105	8	47	47	NUM
ajst-20192	105	9	-	-	SYM
ajst-20192	105	10	52	52	NUM
ajst-20192	105	11	.	.	PUNCT
ajst-20192	106	1	[	[	X
ajst-20192	106	2	7	7	NUM
ajst-20192	106	3	]	]	X
ajst-20192	106	4	perrotta	perrotta	PROPN
ajst-20192	106	5	,	,	PUNCT
ajst-20192	106	6	s.	s.	PROPN
ajst-20192	106	7	;	;	PUNCT
ajst-20192	106	8	gallagher	gallagher	PROPN
ajst-20192	106	9	,	,	PUNCT
ajst-20192	106	10	p.	p.	PROPN
ajst-20192	106	11	g.	g.	PROPN
ajst-20192	106	12	;	;	PUNCT
ajst-20192	106	13	mohandas	mohandas	PROPN
ajst-20192	106	14	,	,	PUNCT
ajst-20192	106	15	n.	n.	ADJ
ajst-20192	106	16	hereditary	hereditary	ADJ
ajst-20192	106	17	spherocytosis	spherocytosis	NOUN
ajst-20192	106	18	.	.	PUNCT
ajst-20192	107	1	lancet	lancet	PROPN
ajst-20192	107	2	2008	2008	NUM
ajst-20192	107	3	,	,	PUNCT
ajst-20192	107	4	372	372	NUM
ajst-20192	107	5	,	,	PUNCT
ajst-20192	107	6	1411	1411	NUM
ajst-20192	107	7	-	-	SYM
ajst-20192	107	8	1426	1426	NUM
ajst-20192	107	9	.	.	PUNCT
ajst-20192	108	1	[	[	X
ajst-20192	108	2	8	8	NUM
ajst-20192	108	3	]	]	X
ajst-20192	108	4	arakawa	arakawa	PROPN
ajst-20192	108	5	,	,	PUNCT
ajst-20192	108	6	t.	t.	PROPN
ajst-20192	108	7	;	;	PUNCT
ajst-20192	108	8	kobayashi	kobayashi	PROPN
ajst-20192	108	9	yurugi	yurugi	PROPN
ajst-20192	108	10	,	,	PUNCT
ajst-20192	108	11	t.	t.	PROPN
ajst-20192	108	12	;	;	PUNCT
ajst-20192	108	13	alguel	alguel	PROPN
ajst-20192	108	14	,	,	PUNCT
ajst-20192	108	15	y.	y.	PROPN
ajst-20192	108	16	;	;	PUNCT
ajst-20192	108	17	iwanari	iwanari	PROPN
ajst-20192	108	18	,	,	PUNCT
ajst-20192	108	19	h.	h.	PROPN
ajst-20192	108	20	;	;	PUNCT
ajst-20192	108	21	hatae	hatae	PROPN
ajst-20192	108	22	,	,	PUNCT
ajst-20192	108	23	h.	h.	PROPN
ajst-20192	108	24	;	;	PUNCT
ajst-20192	108	25	iwata	iwata	NOUN
ajst-20192	108	26	,	,	PUNCT
ajst-20192	108	27	m.	m.	NOUN
ajst-20192	108	28	;	;	PUNCT
ajst-20192	108	29	abe	abe	PROPN
ajst-20192	108	30	,	,	PUNCT
ajst-20192	108	31	y.	y.	PROPN
ajst-20192	108	32	;	;	PUNCT
ajst-20192	108	33	hino	hino	PROPN
ajst-20192	108	34	,	,	PUNCT
ajst-20192	108	35	t.	t.	PROPN
ajst-20192	108	36	;	;	PUNCT
ajst-20192	108	37	ikeda	ikeda	PROPN
ajst-20192	108	38	-	-	PUNCT
ajst-20192	108	39	suno	suno	PROPN
ajst-20192	108	40	,	,	PUNCT
ajst-20192	108	41	c.	c.	PROPN
ajst-20192	108	42	;	;	PUNCT
ajst-20192	108	43	kuma	kuma	PROPN
ajst-20192	108	44	,	,	PUNCT
ajst-20192	108	45	h.	h.	PROPN
ajst-20192	108	46	;	;	PUNCT
ajst-20192	108	47	kang	kang	PROPN
ajst-20192	108	48	,	,	PUNCT
ajst-20192	108	49	d.	d.	PROPN
ajst-20192	108	50	;	;	PUNCT
ajst-20192	108	51	murata	murata	PROPN
ajst-20192	108	52	,	,	PUNCT
ajst-20192	108	53	t.	t.	PROPN
ajst-20192	108	54	;	;	PUNCT
ajst-20192	108	55	hamakubo	hamakubo	PROPN
ajst-20192	108	56	,	,	PUNCT
ajst-20192	108	57	t.	t.	PROPN
ajst-20192	108	58	;	;	PUNCT
ajst-20192	108	59	cameron	cameron	PROPN
ajst-20192	108	60	,	,	PUNCT
ajst-20192	108	61	a.	a.	PROPN
ajst-20192	108	62	d.	d.	PROPN
ajst-20192	108	63	;	;	PUNCT
ajst-20192	108	64	kobayashi	kobayashi	PROPN
ajst-20192	108	65	,	,	PUNCT
ajst-20192	108	66	t.	t.	PROPN
ajst-20192	108	67	;	;	PUNCT
ajst-20192	108	68	hamasaki	hamasaki	PROPN
ajst-20192	108	69	,	,	PUNCT
ajst-20192	108	70	n.	n.	NOUN
ajst-20192	108	71	;	;	PUNCT
ajst-20192	108	72	iwata	iwata	PROPN
ajst-20192	108	73	,	,	PUNCT
ajst-20192	108	74	s.	s.	PROPN
ajst-20192	108	75	crystal	crystal	PROPN
ajst-20192	108	76	structure	structure	NOUN
ajst-20192	108	77	of	of	ADP
ajst-20192	108	78	the	the	DET
ajst-20192	108	79	anion	anion	NOUN
ajst-20192	108	80	exchanger	exchanger	NOUN
ajst-20192	108	81	domain	domain	NOUN
ajst-20192	108	82	of	of	ADP
ajst-20192	108	83	human	human	ADJ
ajst-20192	108	84	erythrocyte	erythrocyte	PROPN
ajst-20192	108	85	band	band	NOUN
ajst-20192	108	86	3	3	NUM
ajst-20192	108	87	.	.	PUNCT
ajst-20192	109	1	science	science	NOUN
ajst-20192	109	2	2015	2015	NUM
ajst-20192	109	3	,	,	PUNCT
ajst-20192	109	4	350	350	NUM
ajst-20192	109	5	(	(	PUNCT
ajst-20192	109	6	6261	6261	NUM
ajst-20192	109	7	)	)	PUNCT
ajst-20192	109	8	,	,	PUNCT
ajst-20192	109	9	680	680	NUM
ajst-20192	109	10	-	-	SYM
ajst-20192	109	11	684	684	NUM
ajst-20192	109	12	.	.	PUNCT
ajst-20192	110	1	[	[	X
ajst-20192	110	2	9	9	NUM
ajst-20192	110	3	]	]	X
ajst-20192	110	4	huang	huang	PROPN
ajst-20192	110	5	,	,	PUNCT
ajst-20192	110	6	j.	j.	PROPN
ajst-20192	110	7	;	;	PUNCT
ajst-20192	110	8	rauscher	rauscher	PROPN
ajst-20192	110	9	,	,	PUNCT
ajst-20192	110	10	s.	s.	PROPN
ajst-20192	110	11	;	;	PUNCT
ajst-20192	110	12	nawrocki	nawrocki	PROPN
ajst-20192	110	13	,	,	PUNCT
ajst-20192	110	14	g.	g.	PROPN
ajst-20192	110	15	;	;	PUNCT
ajst-20192	110	16	ran	run	VERB
ajst-20192	110	17	,	,	PUNCT
ajst-20192	110	18	t.	t.	PROPN
ajst-20192	110	19	;	;	PUNCT
ajst-20192	110	20	feig	feig	NOUN
ajst-20192	110	21	,	,	PUNCT
ajst-20192	110	22	m.	m.	NOUN
ajst-20192	110	23	;	;	PUNCT
ajst-20192	110	24	de	de	X
ajst-20192	110	25	groot	groot	PROPN
ajst-20192	110	26	,	,	PUNCT
ajst-20192	110	27	b.	b.	PROPN
ajst-20192	110	28	l.	l.	PROPN
ajst-20192	110	29	;	;	PUNCT
ajst-20192	110	30	grubmueller	grubmueller	PROPN
ajst-20192	110	31	,	,	PUNCT
ajst-20192	110	32	h.	h.	PROPN
ajst-20192	110	33	;	;	PUNCT
ajst-20192	110	34	mackerell	mackerell	ADJ
ajst-20192	110	35	,	,	PUNCT
ajst-20192	110	36	a.	a.	PROPN
ajst-20192	110	37	d.	d.	PROPN
ajst-20192	110	38	,	,	PUNCT
ajst-20192	110	39	jr	jr	PROPN
ajst-20192	110	40	.	.	PROPN
ajst-20192	110	41	charmm36	charmm36	PROPN
ajst-20192	110	42	:	:	PUNCT
ajst-20192	110	43	an	an	DET
ajst-20192	110	44	improved	improved	ADJ
ajst-20192	110	45	force	force	NOUN
ajst-20192	110	46	field	field	NOUN
ajst-20192	110	47	for	for	ADP
ajst-20192	110	48	folded	folded	ADJ
ajst-20192	110	49	and	and	CCONJ
ajst-20192	110	50	intrinsically	intrinsically	ADV
ajst-20192	110	51	disordered	disordered	ADJ
ajst-20192	110	52	proteins	protein	NOUN
ajst-20192	110	53	.	.	PUNCT
ajst-20192	111	1	biophys	biophy	NOUN
ajst-20192	111	2	.	.	PUNCT
ajst-20192	112	1	j	j	PROPN
ajst-20192	112	2	2017	2017	NUM
ajst-20192	112	3	,	,	PUNCT
ajst-20192	112	4	112	112	NUM
ajst-20192	112	5	(	(	PUNCT
ajst-20192	112	6	3	3	NUM
ajst-20192	112	7	)	)	PUNCT
ajst-20192	112	8	,	,	PUNCT
ajst-20192	112	9	175a-176a	175a-176a	NUM
ajst-20192	112	10	.	.	PUNCT
ajst-20192	113	1	[	[	X
ajst-20192	113	2	10	10	NUM
ajst-20192	113	3	]	]	X
ajst-20192	113	4	lee	lee	PROPN
ajst-20192	113	5	,	,	PUNCT
ajst-20192	113	6	j.	j.	PROPN
ajst-20192	113	7	;	;	PUNCT
ajst-20192	113	8	cheng	cheng	PROPN
ajst-20192	113	9	,	,	PUNCT
ajst-20192	113	10	x.	x.	PROPN
ajst-20192	113	11	;	;	PUNCT
ajst-20192	113	12	swails	swails	PROPN
ajst-20192	113	13	,	,	PUNCT
ajst-20192	113	14	j.	j.	PROPN
ajst-20192	113	15	m.	m.	PROPN
ajst-20192	113	16	;	;	PUNCT
ajst-20192	113	17	yeom	yeom	PROPN
ajst-20192	113	18	,	,	PUNCT
ajst-20192	113	19	m.	m.	NOUN
ajst-20192	113	20	s.	s.	PROPN
ajst-20192	113	21	;	;	PUNCT
ajst-20192	113	22	eastman	eastman	PROPN
ajst-20192	113	23	,	,	PUNCT
ajst-20192	113	24	p.	p.	PROPN
ajst-20192	113	25	k.	k.	PROPN
ajst-20192	113	26	;	;	PUNCT
ajst-20192	113	27	lemkul	lemkul	PROPN
ajst-20192	113	28	,	,	PUNCT
ajst-20192	113	29	j.	j.	PROPN
ajst-20192	113	30	a.	a.	PROPN
ajst-20192	113	31	;	;	PUNCT
ajst-20192	113	32	wei	wei	PROPN
ajst-20192	113	33	,	,	PUNCT
ajst-20192	113	34	s.	s.	PROPN
ajst-20192	113	35	;	;	PUNCT
ajst-20192	113	36	buckner	buckner	PROPN
ajst-20192	113	37	,	,	PUNCT
ajst-20192	113	38	j.	j.	PROPN
ajst-20192	113	39	;	;	PUNCT
ajst-20192	113	40	jeong	jeong	PROPN
ajst-20192	113	41	,	,	PUNCT
ajst-20192	113	42	j.	j.	PROPN
ajst-20192	113	43	c.	c.	PROPN
ajst-20192	113	44	;	;	PUNCT
ajst-20192	113	45	qi	qi	PROPN
ajst-20192	113	46	,	,	PUNCT
ajst-20192	113	47	y.	y.	PROPN
ajst-20192	113	48	;	;	PUNCT
ajst-20192	113	49	jo	jo	PROPN
ajst-20192	113	50	,	,	PUNCT
ajst-20192	113	51	s.	s.	PROPN
ajst-20192	113	52	;	;	PUNCT
ajst-20192	113	53	pande	pande	NOUN
ajst-20192	113	54	,	,	PUNCT
ajst-20192	113	55	v.	v.	CCONJ
ajst-20192	113	56	s.	s.	PROPN
ajst-20192	113	57	;	;	PUNCT
ajst-20192	113	58	case	case	NOUN
ajst-20192	113	59	,	,	PUNCT
ajst-20192	113	60	d.	d.	PROPN
ajst-20192	113	61	a.	a.	PROPN
ajst-20192	113	62	;	;	PUNCT
ajst-20192	113	63	brooks	brooks	PROPN
ajst-20192	113	64	,	,	PUNCT
ajst-20192	113	65	c.	c.	PROPN
ajst-20192	113	66	l.	l.	PROPN
ajst-20192	113	67	,	,	PUNCT
ajst-20192	113	68	iii	iii	PROPN
ajst-20192	113	69	;	;	PUNCT
ajst-20192	113	70	mackerell	mackerell	ADJ
ajst-20192	113	71	,	,	PUNCT
ajst-20192	113	72	a.	a.	PROPN
ajst-20192	113	73	d.	d.	PROPN
ajst-20192	113	74	,	,	PUNCT
ajst-20192	113	75	jr	jr	PROPN
ajst-20192	113	76	.	.	PROPN
ajst-20192	113	77	;	;	PUNCT
ajst-20192	113	78	klauda	klauda	PROPN
ajst-20192	113	79	,	,	PUNCT
ajst-20192	113	80	j.	j.	PROPN
ajst-20192	113	81	b.	b.	PROPN
ajst-20192	113	82	;	;	PUNCT
ajst-20192	113	83	i	i	PROPN
ajst-20192	113	84	m	m	PROPN
ajst-20192	113	85	,	,	PUNCT
ajst-20192	113	86	w.	w.	PROPN
ajst-20192	113	87	charmm	charmm	PROPN
ajst-20192	113	88	-	-	PUNCT
ajst-20192	113	89	gui	gui	NOUN
ajst-20192	113	90	input	input	NOUN
ajst-20192	113	91	generator	generator	NOUN
ajst-20192	113	92	for	for	ADP
ajst-20192	113	93	namd	namd	NOUN
ajst-20192	113	94	,	,	PUNCT
ajst-20192	113	95	gromacs	gromacs	PROPN
ajst-20192	113	96	,	,	PUNCT
ajst-20192	113	97	amber	amber	PROPN
ajst-20192	113	98	,	,	PUNCT
ajst-20192	113	99	openmm	openmm	PROPN
ajst-20192	113	100	,	,	PUNCT
ajst-20192	113	101	and	and	CCONJ
ajst-20192	113	102	charmm	charmm	NOUN
ajst-20192	113	103	/	/	SYM
ajst-20192	113	104	openmm	openmm	NOUN
ajst-20192	113	105	simulations	simulation	NOUN
ajst-20192	113	106	using	use	VERB
ajst-20192	113	107	the	the	DET
ajst-20192	113	108	charmm36	charmm36	NOUN
ajst-20192	113	109	additive	additive	ADJ
ajst-20192	113	110	force	force	NOUN
ajst-20192	113	111	field	field	NOUN
ajst-20192	113	112	.	.	PUNCT
ajst-20192	114	1	j.	j.	PROPN
ajst-20192	114	2	chem	chem	PROPN
ajst-20192	114	3	.	.	PUNCT
ajst-20192	115	1	theory	theory	NOUN
ajst-20192	115	2	comput	comput	NOUN
ajst-20192	115	3	.	.	PUNCT
ajst-20192	116	1	2016	2016	NUM
ajst-20192	116	2	,	,	PUNCT
ajst-20192	116	3	12	12	NUM
ajst-20192	116	4	(	(	PUNCT
ajst-20192	116	5	1	1	NUM
ajst-20192	116	6	)	)	PUNCT
ajst-20192	116	7	,	,	PUNCT
ajst-20192	116	8	405	405	NUM
ajst-20192	116	9	-	-	SYM
ajst-20192	116	10	413	413	NUM
ajst-20192	116	11	.	.	PUNCT
ajst-20192	117	1	[	[	X
ajst-20192	117	2	11	11	NUM
ajst-20192	117	3	]	]	X
ajst-20192	117	4	abraham	abraham	PROPN
ajst-20192	117	5	,	,	PUNCT
ajst-20192	117	6	m.	m.	PROPN
ajst-20192	117	7	j.	j.	PROPN
ajst-20192	117	8	;	;	PUNCT
ajst-20192	117	9	murtola	murtola	PROPN
ajst-20192	117	10	,	,	PUNCT
ajst-20192	117	11	t.	t.	PROPN
ajst-20192	117	12	;	;	PUNCT
ajst-20192	117	13	schulz	schulz	PROPN
ajst-20192	117	14	,	,	PUNCT
ajst-20192	117	15	r.	r.	PROPN
ajst-20192	117	16	;	;	PUNCT
ajst-20192	117	17	páll	páll	PROPN
ajst-20192	117	18	,	,	PUNCT
ajst-20192	117	19	s.	s.	PROPN
ajst-20192	117	20	;	;	PUNCT
ajst-20192	117	21	smith	smith	PROPN
ajst-20192	117	22	,	,	PUNCT
ajst-20192	117	23	j.	j.	PROPN
ajst-20192	117	24	c.	c.	PROPN
ajst-20192	117	25	;	;	PUNCT
ajst-20192	117	26	hess	hess	PROPN
ajst-20192	117	27	,	,	PUNCT
ajst-20192	117	28	b.	b.	PROPN
ajst-20192	117	29	;	;	PUNCT
ajst-20192	117	30	lindahl	lindahl	PROPN
ajst-20192	117	31	,	,	PUNCT
ajst-20192	117	32	e.	e.	PROPN
ajst-20192	117	33	gromacs	gromacs	PROPN
ajst-20192	117	34	:	:	PUNCT
ajst-20192	117	35	high	high	ADJ
ajst-20192	117	36	performance	performance	NOUN
ajst-20192	117	37	molecular	molecular	ADJ
ajst-20192	117	38	simulations	simulation	NOUN
ajst-20192	117	39	through	through	ADP
ajst-20192	117	40	multi	multi	ADJ
ajst-20192	117	41	-	-	ADJ
ajst-20192	117	42	level	level	ADJ
ajst-20192	117	43	parallelism	parallelism	NOUN
ajst-20192	117	44	from	from	ADP
ajst-20192	117	45	laptops	laptop	NOUN
ajst-20192	117	46	to	to	ADP
ajst-20192	117	47	supercomputers	supercomputer	NOUN
ajst-20192	117	48	.	.	PUNCT
ajst-20192	118	1	softwarex	softwarex	PROPN
ajst-20192	118	2	2015	2015	NUM
ajst-20192	118	3	,	,	PUNCT
ajst-20192	118	4	1	1	NUM
ajst-20192	118	5	-	-	SYM
ajst-20192	118	6	2	2	NUM
ajst-20192	118	7	,	,	PUNCT
ajst-20192	118	8	19	19	NUM
ajst-20192	118	9	-	-	SYM
ajst-20192	118	10	25	25	NUM
ajst-20192	118	11	.	.	PUNCT
ajst-20192	119	1	[	[	X
ajst-20192	119	2	12	12	NUM
ajst-20192	119	3	]	]	X
ajst-20192	119	4	tribello	tribello	PROPN
ajst-20192	119	5	,	,	PUNCT
ajst-20192	119	6	g.	g.	PROPN
ajst-20192	119	7	a.	a.	PROPN
ajst-20192	119	8	;	;	PUNCT
ajst-20192	119	9	bonomi	bonomi	NOUN
ajst-20192	119	10	,	,	PUNCT
ajst-20192	119	11	m.	m.	NOUN
ajst-20192	119	12	;	;	PUNCT
ajst-20192	119	13	branduardi	branduardi	NOUN
ajst-20192	119	14	,	,	PUNCT
ajst-20192	119	15	d.	d.	PROPN
ajst-20192	119	16	;	;	PUNCT
ajst-20192	119	17	camilloni	camilloni	PROPN
ajst-20192	119	18	,	,	PUNCT
ajst-20192	119	19	c.	c.	NOUN
ajst-20192	119	20	;	;	PUNCT
ajst-20192	119	21	bussi	bussi	ADJ
ajst-20192	119	22	,	,	PUNCT
ajst-20192	119	23	g.	g.	PROPN
ajst-20192	119	24	plumed	plume	VERB
ajst-20192	119	25	2	2	NUM
ajst-20192	119	26	:	:	PUNCT
ajst-20192	119	27	new	new	ADJ
ajst-20192	119	28	feathers	feather	NOUN
ajst-20192	119	29	for	for	ADP
ajst-20192	119	30	an	an	DET
ajst-20192	119	31	old	old	ADJ
ajst-20192	119	32	bird	bird	NOUN
ajst-20192	119	33	.	.	PUNCT
ajst-20192	120	1	comput	comput	NOUN
ajst-20192	120	2	.	.	PUNCT
ajst-20192	121	1	phys	phy	NOUN
ajst-20192	121	2	.	.	PUNCT
ajst-20192	122	1	commun	commun	PROPN
ajst-20192	122	2	.	.	PUNCT
ajst-20192	123	1	2014	2014	NUM
ajst-20192	123	2	,	,	PUNCT
ajst-20192	123	3	185	185	NUM
ajst-20192	123	4	(	(	PUNCT
ajst-20192	123	5	2	2	NUM
ajst-20192	123	6	)	)	PUNCT
ajst-20192	123	7	,	,	PUNCT
ajst-20192	123	8	604	604	NUM
ajst-20192	123	9	-	-	SYM
ajst-20192	123	10	613	613	NUM
ajst-20192	123	11	.	.	PUNCT
ajst-20192	124	1	[	[	X
ajst-20192	124	2	13	13	NUM
ajst-20192	124	3	]	]	PUNCT
ajst-20192	124	4	evans	evans	PROPN
ajst-20192	124	5	,	,	PUNCT
ajst-20192	124	6	d.	d.	PROPN
ajst-20192	124	7	j.	j.	PROPN
ajst-20192	124	8	;	;	PUNCT
ajst-20192	124	9	holian	holian	PROPN
ajst-20192	124	10	,	,	PUNCT
ajst-20192	124	11	b.	b.	PROPN
ajst-20192	124	12	l.	l.	PROPN
ajst-20192	124	13	the	the	DET
ajst-20192	124	14	nose	nose	NOUN
ajst-20192	124	15	–	–	PUNCT
ajst-20192	124	16	hoover	hoover	NOUN
ajst-20192	124	17	thermostat	thermostat	NOUN
ajst-20192	124	18	.	.	PUNCT
ajst-20192	125	1	j.	j.	PROPN
ajst-20192	125	2	chem	chem	PROPN
ajst-20192	125	3	.	.	PUNCT
ajst-20192	126	1	phys	phy	NOUN
ajst-20192	126	2	.	.	PUNCT
ajst-20192	127	1	1985	1985	NUM
ajst-20192	127	2	,	,	PUNCT
ajst-20192	127	3	83	83	NUM
ajst-20192	127	4	(	(	PUNCT
ajst-20192	127	5	8)	8)	NUM
ajst-20192	127	6	,	,	PUNCT
ajst-20192	127	7	4069	4069	NUM
ajst-20192	127	8	-	-	SYM
ajst-20192	127	9	4074	4074	NUM
ajst-20192	127	10	.	.	PUNCT
ajst-20192	128	1	[	[	X
ajst-20192	128	2	14	14	NUM
ajst-20192	128	3	]	]	X
ajst-20192	128	4	parrinello	parrinello	ADJ
ajst-20192	128	5	,	,	PUNCT
ajst-20192	128	6	m.	m.	NOUN
ajst-20192	128	7	;	;	PUNCT
ajst-20192	128	8	rahman	rahman	PROPN
ajst-20192	128	9	,	,	PUNCT
ajst-20192	128	10	a.	a.	NOUN
ajst-20192	128	11	polymorphic	polymorphic	ADJ
ajst-20192	128	12	transitions	transition	NOUN
ajst-20192	128	13	in	in	ADP
ajst-20192	128	14	single	single	ADJ
ajst-20192	128	15	crystals	crystal	NOUN
ajst-20192	128	16	:	:	PUNCT
ajst-20192	128	17	a	a	DET
ajst-20192	128	18	new	new	ADJ
ajst-20192	128	19	molecular	molecular	ADJ
ajst-20192	128	20	dynamics	dynamic	NOUN
ajst-20192	128	21	method	method	NOUN
ajst-20192	128	22	.	.	PUNCT
ajst-20192	129	1	j.	j.	PROPN
ajst-20192	129	2	appl	appl	PROPN
ajst-20192	129	3	.	.	PUNCT
ajst-20192	130	1	phys	phy	NOUN
ajst-20192	130	2	.	.	PUNCT
ajst-20192	131	1	1981	1981	NUM
ajst-20192	131	2	,	,	PUNCT
ajst-20192	131	3	52	52	NUM
ajst-20192	131	4	(	(	PUNCT
ajst-20192	131	5	12	12	NUM
ajst-20192	131	6	)	)	PUNCT
ajst-20192	131	7	,	,	PUNCT
ajst-20192	131	8	7182	7182	NUM
ajst-20192	131	9	-	-	SYM
ajst-20192	131	10	7190	7190	NUM
ajst-20192	131	11	.	.	PUNCT
ajst-20192	132	1	[	[	X
ajst-20192	132	2	15	15	NUM
ajst-20192	132	3	]	]	X
ajst-20192	132	4	darden	darden	PROPN
ajst-20192	132	5	,	,	PUNCT
ajst-20192	132	6	t.	t.	PROPN
ajst-20192	132	7	;	;	PUNCT
ajst-20192	132	8	york	york	PROPN
ajst-20192	132	9	,	,	PUNCT
ajst-20192	132	10	d.	d.	PROPN
ajst-20192	132	11	;	;	PUNCT
ajst-20192	132	12	pedersen	pedersen	PROPN
ajst-20192	132	13	,	,	PUNCT
ajst-20192	132	14	l.	l.	PROPN
ajst-20192	132	15	particle	particle	PROPN
ajst-20192	132	16	mesh	mesh	PROPN
ajst-20192	132	17	ewald	ewald	PROPN
ajst-20192	132	18	:	:	PUNCT
ajst-20192	132	19	an	an	DET
ajst-20192	132	20	n	n	PRON
ajst-20192	132	21	⋅log(n	⋅log(n	NOUN
ajst-20192	132	22	)	)	PUNCT
ajst-20192	132	23	method	method	NOUN
ajst-20192	132	24	for	for	ADP
ajst-20192	132	25	ewald	ewald	PROPN
ajst-20192	132	26	sums	sum	NOUN
ajst-20192	132	27	in	in	ADP
ajst-20192	132	28	large	large	ADJ
ajst-20192	132	29	systems	system	NOUN
ajst-20192	132	30	.	.	PUNCT
ajst-20192	133	1	j.	j.	PROPN
ajst-20192	133	2	chem	chem	PROPN
ajst-20192	133	3	.	.	PUNCT
ajst-20192	134	1	phys	phy	NOUN
ajst-20192	134	2	.	.	PUNCT
ajst-20192	135	1	1993	1993	NUM
ajst-20192	135	2	,	,	PUNCT
ajst-20192	135	3	98	98	NUM
ajst-20192	135	4	(	(	PUNCT
ajst-20192	135	5	12	12	NUM
ajst-20192	135	6	)	)	PUNCT
ajst-20192	135	7	,	,	PUNCT
ajst-20192	135	8	10089	10089	NUM
ajst-20192	135	9	-	-	SYM
ajst-20192	135	10	10092	10092	NUM
ajst-20192	135	11	.	.	PUNCT
ajst-20192	136	1	[	[	X
ajst-20192	136	2	16	16	NUM
ajst-20192	136	3	]	]	X
ajst-20192	136	4	hess	hess	PROPN
ajst-20192	136	5	,	,	PUNCT
ajst-20192	136	6	b.	b.	PROPN
ajst-20192	137	1	p	p	PROPN
ajst-20192	137	2	-	-	PUNCT
ajst-20192	137	3	lincs	lincs	PROPN
ajst-20192	137	4	:	:	PUNCT
ajst-20192	137	5	a	a	DET
ajst-20192	137	6	parallel	parallel	ADJ
ajst-20192	137	7	linear	linear	NOUN
ajst-20192	137	8	constraint	constraint	NOUN
ajst-20192	137	9	solver	solver	VERB
ajst-20192	137	10	for	for	ADP
ajst-20192	137	11	molecular	molecular	ADJ
ajst-20192	137	12	simulation	simulation	NOUN
ajst-20192	137	13	.	.	PUNCT
ajst-20192	138	1	j.	j.	PROPN
ajst-20192	138	2	chem	chem	PROPN
ajst-20192	138	3	.	.	PUNCT
ajst-20192	139	1	theory	theory	NOUN
ajst-20192	139	2	comput	comput	NOUN
ajst-20192	139	3	.	.	PUNCT
ajst-20192	140	1	2008	2008	NUM
ajst-20192	140	2	,	,	PUNCT
ajst-20192	140	3	4	4	NUM
ajst-20192	140	4	(	(	PUNCT
ajst-20192	140	5	1	1	NUM
ajst-20192	140	6	)	)	PUNCT
ajst-20192	140	7	,	,	PUNCT
ajst-20192	140	8	116	116	NUM
ajst-20192	140	9	-	-	SYM
ajst-20192	140	10	122	122	NUM
ajst-20192	140	11	.	.	PUNCT
ajst-20192	141	1	[	[	X
ajst-20192	141	2	17	17	NUM
ajst-20192	141	3	]	]	X
ajst-20192	141	4	humphrey	humphrey	PROPN
ajst-20192	141	5	,	,	PUNCT
ajst-20192	141	6	w.	w.	PROPN
ajst-20192	141	7	;	;	PUNCT
ajst-20192	141	8	dalke	dalke	PROPN
ajst-20192	141	9	,	,	PUNCT
ajst-20192	141	10	a.	a.	NOUN
ajst-20192	141	11	;	;	PUNCT
ajst-20192	141	12	schulten	schulten	VERB
ajst-20192	141	13	,	,	PUNCT
ajst-20192	141	14	k.	k.	PROPN
ajst-20192	141	15	vmd	vmd	PROPN
ajst-20192	141	16	:	:	PUNCT
ajst-20192	141	17	visual	visual	ADJ
ajst-20192	141	18	molecular	molecular	ADJ
ajst-20192	141	19	dynamics	dynamic	NOUN
ajst-20192	141	20	.	.	PUNCT
ajst-20192	142	1	j.	j.	PROPN
ajst-20192	142	2	mol	mol	PROPN
ajst-20192	142	3	.	.	PUNCT
ajst-20192	142	4	graphics	graphic	NOUN
ajst-20192	142	5	1996	1996	NUM
ajst-20192	142	6	,	,	PUNCT
ajst-20192	142	7	14	14	NUM
ajst-20192	142	8	(	(	PUNCT
ajst-20192	142	9	1	1	NUM
ajst-20192	142	10	)	)	PUNCT
ajst-20192	142	11	,	,	PUNCT
ajst-20192	142	12	33	33	NUM
ajst-20192	142	13	-	-	SYM
ajst-20192	142	14	38	38	NUM
ajst-20192	142	15	.	.	PUNCT
ajst-20192	143	1	[	[	X
ajst-20192	143	2	18	18	NUM
ajst-20192	143	3	]	]	X
ajst-20192	143	4	chu	chu	PROPN
ajst-20192	143	5	,	,	PUNCT
ajst-20192	143	6	c.	c.	PROPN
ajst-20192	143	7	;	;	PUNCT
ajst-20192	143	8	woods	wood	NOUN
ajst-20192	143	9	,	,	PUNCT
ajst-20192	143	10	n.	n.	NOUN
ajst-20192	143	11	;	;	PUNCT
ajst-20192	143	12	sawasdee	sawasdee	PROPN
ajst-20192	143	13	,	,	PUNCT
ajst-20192	143	14	n.	n.	NOUN
ajst-20192	143	15	;	;	PUNCT
ajst-20192	143	16	guizouarn	guizouarn	PROPN
ajst-20192	143	17	,	,	PUNCT
ajst-20192	143	18	h.	h.	PROPN
ajst-20192	143	19	;	;	PUNCT
ajst-20192	143	20	pellissier	pellissier	NOUN
ajst-20192	143	21	,	,	PUNCT
ajst-20192	143	22	b.	b.	PROPN
ajst-20192	143	23	;	;	PUNCT
ajst-20192	143	24	borgese	borgese	PROPN
ajst-20192	143	25	,	,	PUNCT
ajst-20192	143	26	f.	f.	PROPN
ajst-20192	143	27	;	;	PUNCT
ajst-20192	143	28	yenchitsomanus	yenchitsomanus	PROPN
ajst-20192	143	29	,	,	PUNCT
ajst-20192	143	30	p.-t	p.-t	NOUN
ajst-20192	143	31	.	.	PUNCT
ajst-20192	143	32	;	;	PUNCT
ajst-20192	143	33	gowrishankar	gowrishankar	PROPN
ajst-20192	143	34	,	,	PUNCT
ajst-20192	143	35	m.	m.	NOUN
ajst-20192	143	36	;	;	PUNCT
ajst-20192	143	37	cordat	cordat	NOUN
ajst-20192	143	38	,	,	PUNCT
ajst-20192	143	39	e.	e.	PROPN
ajst-20192	143	40	band	band	PROPN
ajst-20192	143	41	3	3	NUM
ajst-20192	143	42	edmonton	edmonton	PROPN
ajst-20192	143	43	i	i	PRON
ajst-20192	143	44	,	,	PUNCT
ajst-20192	143	45	a	a	DET
ajst-20192	143	46	novel	novel	ADJ
ajst-20192	143	47	mutant	mutant	NOUN
ajst-20192	143	48	of	of	ADP
ajst-20192	143	49	the	the	DET
ajst-20192	143	50	anion	anion	NOUN
ajst-20192	143	51	exchanger	exchanger	NOUN
ajst-20192	143	52	1	1	NUM
ajst-20192	143	53	causing	cause	VERB
ajst-20192	143	54	spherocytosis	spherocytosis	NOUN
ajst-20192	143	55	and	and	CCONJ
ajst-20192	143	56	distal	distal	ADJ
ajst-20192	143	57	renal	renal	ADJ
ajst-20192	143	58	tubular	tubular	ADJ
ajst-20192	143	59	acidosis	acidosis	NOUN
ajst-20192	143	60	.	.	PUNCT
ajst-20192	144	1	biophys	biophy	NOUN
ajst-20192	144	2	.	.	PUNCT
ajst-20192	145	1	j	j	PROPN
ajst-20192	145	2	2010	2010	NUM
ajst-20192	145	3	,	,	PUNCT
ajst-20192	145	4	426	426	NUM
ajst-20192	145	5	,	,	PUNCT
ajst-20192	145	6	379	379	NUM
ajst-20192	145	7	-	-	SYM
ajst-20192	145	8	388	388	NUM
ajst-20192	145	9	.	.	PUNCT