id	sid	tid	token	lemma	pos
ajst-25630	1	1	academic	academic	ADJ
ajst-25630	1	2	journal	journal	NOUN
ajst-25630	1	3	of	of	ADP
ajst-25630	1	4	science	science	NOUN
ajst-25630	1	5	and	and	CCONJ
ajst-25630	1	6	technology	technology	NOUN
ajst-25630	1	7	issn	issn	NOUN
ajst-25630	1	8	:	:	PUNCT
ajst-25630	1	9	2771	2771	NUM
ajst-25630	1	10	-	-	SYM
ajst-25630	1	11	3032	3032	NUM
ajst-25630	1	12	|	|	NOUN
ajst-25630	1	13	vol	vol	NOUN
ajst-25630	1	14	.	.	PROPN
ajst-25630	2	1	12	12	NUM
ajst-25630	2	2	,	,	PUNCT
ajst-25630	2	3	no	no	INTJ
ajst-25630	2	4	.	.	NOUN
ajst-25630	2	5	2	2	NUM
ajst-25630	2	6	,	,	PUNCT
ajst-25630	2	7	2024	2024	NUM
ajst-25630	2	8	217	217	NUM
ajst-25630	2	9	novel	novel	ADJ
ajst-25630	2	10	biomarkers	biomarker	NOUN
ajst-25630	2	11	for	for	ADP
ajst-25630	2	12	kidney	kidney	NOUN
ajst-25630	2	13	disease	disease	NOUN
ajst-25630	2	14	:	:	PUNCT
ajst-25630	2	15	new	new	ADJ
ajst-25630	2	16	frontiers	frontier	NOUN
ajst-25630	2	17	in	in	ADP
ajst-25630	2	18	early	early	ADJ
ajst-25630	2	19	diagnosis	diagnosis	NOUN
ajst-25630	2	20	and	and	CCONJ
ajst-25630	2	21	monitoring	monitoring	NOUN
ajst-25630	2	22	can	can	AUX
ajst-25630	2	23	pu	pu	X
ajst-25630	2	24	,	,	PUNCT
ajst-25630	2	25	wenbo	wenbo	ADP
ajst-25630	2	26	xu	xu	PROPN
ajst-25630	3	1	*	*	PUNCT
ajst-25630	4	1	school	school	NOUN
ajst-25630	4	2	of	of	ADP
ajst-25630	4	3	health	health	NOUN
ajst-25630	4	4	and	and	CCONJ
ajst-25630	4	5	medical	medical	ADJ
ajst-25630	4	6	technology	technology	NOUN
ajst-25630	4	7	,	,	PUNCT
ajst-25630	4	8	chengdu	chengdu	PROPN
ajst-25630	4	9	neusoft	neusoft	PROPN
ajst-25630	4	10	university	university	PROPN
ajst-25630	4	11	,	,	PUNCT
ajst-25630	4	12	chengdu	chengdu	PROPN
ajst-25630	4	13	,	,	PUNCT
ajst-25630	4	14	sichuan	sichuan	PROPN
ajst-25630	4	15	611844	611844	NUM
ajst-25630	4	16	,	,	PUNCT
ajst-25630	4	17	china	china	PROPN
ajst-25630	4	18	*	*	PUNCT
ajst-25630	4	19	corresponding	correspond	VERB
ajst-25630	4	20	author	author	NOUN
ajst-25630	4	21	:	:	PUNCT
ajst-25630	4	22	wenbo	wenbo	PROPN
ajst-25630	5	1	xu	xu	INTJ
ajst-25630	5	2	(	(	PUNCT
ajst-25630	5	3	email	email	NOUN
ajst-25630	5	4	:	:	PUNCT
ajst-25630	5	5	xuwenbo@nsu.edu.cn	xuwenbo@nsu.edu.cn	NOUN
ajst-25630	5	6	)	)	PUNCT
ajst-25630	5	7	abstract	abstract	NOUN
ajst-25630	5	8	:	:	PUNCT
ajst-25630	5	9	kidney	kidney	NOUN
ajst-25630	5	10	diseases	disease	NOUN
ajst-25630	5	11	pose	pose	VERB
ajst-25630	5	12	a	a	DET
ajst-25630	5	13	significant	significant	ADJ
ajst-25630	5	14	threat	threat	NOUN
ajst-25630	5	15	to	to	ADP
ajst-25630	5	16	global	global	ADJ
ajst-25630	5	17	public	public	ADJ
ajst-25630	5	18	health	health	NOUN
ajst-25630	5	19	,	,	PUNCT
ajst-25630	5	20	with	with	ADP
ajst-25630	5	21	early	early	ADJ
ajst-25630	5	22	diagnosis	diagnosis	NOUN
ajst-25630	5	23	and	and	CCONJ
ajst-25630	5	24	accurate	accurate	ADJ
ajst-25630	5	25	monitoring	monitoring	NOUN
ajst-25630	5	26	being	be	AUX
ajst-25630	5	27	crucial	crucial	ADJ
ajst-25630	5	28	for	for	ADP
ajst-25630	5	29	improving	improve	VERB
ajst-25630	5	30	patient	patient	ADJ
ajst-25630	5	31	outcomes	outcome	NOUN
ajst-25630	5	32	.	.	PUNCT
ajst-25630	6	1	however	however	ADV
ajst-25630	6	2	,	,	PUNCT
ajst-25630	6	3	traditional	traditional	ADJ
ajst-25630	6	4	kidney	kidney	NOUN
ajst-25630	6	5	disease	disease	NOUN
ajst-25630	6	6	markers	marker	NOUN
ajst-25630	6	7	such	such	ADJ
ajst-25630	6	8	as	as	ADP
ajst-25630	6	9	serum	serum	NOUN
ajst-25630	6	10	creatinine	creatinine	NOUN
ajst-25630	6	11	and	and	CCONJ
ajst-25630	6	12	blood	blood	NOUN
ajst-25630	6	13	urea	urea	NOUN
ajst-25630	6	14	nitrogen	nitrogen	NOUN
ajst-25630	6	15	have	have	VERB
ajst-25630	6	16	limitations	limitation	NOUN
ajst-25630	6	17	in	in	ADP
ajst-25630	6	18	sensitivity	sensitivity	NOUN
ajst-25630	6	19	and	and	CCONJ
ajst-25630	6	20	specificity	specificity	NOUN
ajst-25630	6	21	.	.	PUNCT
ajst-25630	7	1	in	in	ADP
ajst-25630	7	2	recent	recent	ADJ
ajst-25630	7	3	years	year	NOUN
ajst-25630	7	4	,	,	PUNCT
ajst-25630	7	5	rapid	rapid	ADJ
ajst-25630	7	6	advancements	advancement	NOUN
ajst-25630	7	7	in	in	ADP
ajst-25630	7	8	molecular	molecular	ADJ
ajst-25630	7	9	biology	biology	NOUN
ajst-25630	7	10	and	and	CCONJ
ajst-25630	7	11	proteomics	proteomic	NOUN
ajst-25630	7	12	have	have	AUX
ajst-25630	7	13	led	lead	VERB
ajst-25630	7	14	to	to	ADP
ajst-25630	7	15	the	the	DET
ajst-25630	7	16	discovery	discovery	NOUN
ajst-25630	7	17	of	of	ADP
ajst-25630	7	18	a	a	DET
ajst-25630	7	19	series	series	NOUN
ajst-25630	7	20	of	of	ADP
ajst-25630	7	21	novel	novel	ADJ
ajst-25630	7	22	biomarkers	biomarker	NOUN
ajst-25630	7	23	that	that	PRON
ajst-25630	7	24	are	be	AUX
ajst-25630	7	25	gradually	gradually	ADV
ajst-25630	7	26	being	be	AUX
ajst-25630	7	27	applied	apply	VERB
ajst-25630	7	28	in	in	ADP
ajst-25630	7	29	clinical	clinical	ADJ
ajst-25630	7	30	practice	practice	NOUN
ajst-25630	7	31	.	.	PUNCT
ajst-25630	8	1	this	this	DET
ajst-25630	8	2	review	review	NOUN
ajst-25630	8	3	examines	examine	VERB
ajst-25630	8	4	novel	novel	ADJ
ajst-25630	8	5	kidney	kidney	NOUN
ajst-25630	8	6	disease	disease	NOUN
ajst-25630	8	7	biomarkers	biomarker	NOUN
ajst-25630	8	8	,	,	PUNCT
ajst-25630	8	9	including	include	VERB
ajst-25630	8	10	cystatin	cystatin	PROPN
ajst-25630	8	11	c	c	PROPN
ajst-25630	8	12	(	(	PUNCT
ajst-25630	8	13	cys	cys	PROPN
ajst-25630	8	14	-	-	PUNCT
ajst-25630	8	15	c	c	NOUN
ajst-25630	8	16	)	)	PUNCT
ajst-25630	8	17	,	,	PUNCT
ajst-25630	8	18	neutrophil	neutrophil	ADJ
ajst-25630	8	19	gelatinase	gelatinase	NOUN
ajst-25630	8	20	-	-	PUNCT
ajst-25630	8	21	associated	associate	VERB
ajst-25630	8	22	lipocalin	lipocalin	NOUN
ajst-25630	8	23	(	(	PUNCT
ajst-25630	8	24	ngal	ngal	ADJ
ajst-25630	8	25	)	)	PUNCT
ajst-25630	8	26	,	,	PUNCT
ajst-25630	8	27	and	and	CCONJ
ajst-25630	8	28	kidney	kidney	PROPN
ajst-25630	8	29	injury	injury	PROPN
ajst-25630	8	30	molecule-1	molecule-1	PROPN
ajst-25630	8	31	(	(	PUNCT
ajst-25630	8	32	kim-1	kim-1	NOUN
ajst-25630	8	33	)	)	PUNCT
ajst-25630	8	34	.	.	PUNCT
ajst-25630	9	1	these	these	DET
ajst-25630	9	2	markers	marker	NOUN
ajst-25630	9	3	not	not	PART
ajst-25630	9	4	only	only	ADV
ajst-25630	9	5	reflect	reflect	VERB
ajst-25630	9	6	kidney	kidney	NOUN
ajst-25630	9	7	injury	injury	NOUN
ajst-25630	9	8	earlier	early	ADV
ajst-25630	9	9	and	and	CCONJ
ajst-25630	9	10	more	more	ADV
ajst-25630	9	11	accurately	accurately	ADV
ajst-25630	9	12	but	but	CCONJ
ajst-25630	9	13	may	may	AUX
ajst-25630	9	14	also	also	ADV
ajst-25630	9	15	provide	provide	VERB
ajst-25630	9	16	important	important	ADJ
ajst-25630	9	17	bases	basis	NOUN
ajst-25630	9	18	for	for	ADP
ajst-25630	9	19	kidney	kidney	NOUN
ajst-25630	9	20	disease	disease	NOUN
ajst-25630	9	21	classification	classification	NOUN
ajst-25630	9	22	,	,	PUNCT
ajst-25630	9	23	severity	severity	NOUN
ajst-25630	9	24	assessment	assessment	NOUN
ajst-25630	9	25	,	,	PUNCT
ajst-25630	9	26	and	and	CCONJ
ajst-25630	9	27	prognosis	prognosis	NOUN
ajst-25630	9	28	prediction	prediction	NOUN
ajst-25630	9	29	.	.	PUNCT
ajst-25630	10	1	additionally	additionally	ADV
ajst-25630	10	2	,	,	PUNCT
ajst-25630	10	3	this	this	DET
ajst-25630	10	4	paper	paper	NOUN
ajst-25630	10	5	explores	explore	VERB
ajst-25630	10	6	the	the	DET
ajst-25630	10	7	potential	potential	NOUN
ajst-25630	10	8	of	of	ADP
ajst-25630	10	9	multi	multi	ADJ
ajst-25630	10	10	-	-	NOUN
ajst-25630	10	11	marker	marker	NOUN
ajst-25630	10	12	combined	combine	VERB
ajst-25630	10	13	detection	detection	NOUN
ajst-25630	10	14	strategies	strategy	NOUN
ajst-25630	10	15	in	in	ADP
ajst-25630	10	16	improving	improve	VERB
ajst-25630	10	17	diagnostic	diagnostic	ADJ
ajst-25630	10	18	accuracy	accuracy	NOUN
ajst-25630	10	19	.	.	PUNCT
ajst-25630	11	1	although	although	SCONJ
ajst-25630	11	2	these	these	DET
ajst-25630	11	3	novel	novel	ADJ
ajst-25630	11	4	markers	marker	NOUN
ajst-25630	11	5	show	show	VERB
ajst-25630	11	6	immense	immense	ADJ
ajst-25630	11	7	potential	potential	NOUN
ajst-25630	11	8	,	,	PUNCT
ajst-25630	11	9	they	they	PRON
ajst-25630	11	10	still	still	ADV
ajst-25630	11	11	face	face	VERB
ajst-25630	11	12	challenges	challenge	NOUN
ajst-25630	11	13	such	such	ADJ
ajst-25630	11	14	as	as	ADP
ajst-25630	11	15	standardization	standardization	NOUN
ajst-25630	11	16	and	and	CCONJ
ajst-25630	11	17	cost	cost	NOUN
ajst-25630	11	18	-	-	PUNCT
ajst-25630	11	19	effectiveness	effectiveness	NOUN
ajst-25630	11	20	before	before	ADP
ajst-25630	11	21	widespread	widespread	ADJ
ajst-25630	11	22	clinical	clinical	ADJ
ajst-25630	11	23	application	application	NOUN
ajst-25630	11	24	.	.	PUNCT
ajst-25630	12	1	future	future	ADJ
ajst-25630	12	2	research	research	NOUN
ajst-25630	12	3	should	should	AUX
ajst-25630	12	4	focus	focus	VERB
ajst-25630	12	5	on	on	ADP
ajst-25630	12	6	optimizing	optimize	VERB
ajst-25630	12	7	detection	detection	NOUN
ajst-25630	12	8	methods	method	NOUN
ajst-25630	12	9	,	,	PUNCT
ajst-25630	12	10	establishing	establish	VERB
ajst-25630	12	11	clinical	clinical	ADJ
ajst-25630	12	12	decision	decision	NOUN
ajst-25630	12	13	thresholds	threshold	NOUN
ajst-25630	12	14	,	,	PUNCT
ajst-25630	12	15	and	and	CCONJ
ajst-25630	12	16	evaluating	evaluate	VERB
ajst-25630	12	17	the	the	DET
ajst-25630	12	18	value	value	NOUN
ajst-25630	12	19	of	of	ADP
ajst-25630	12	20	these	these	DET
ajst-25630	12	21	markers	marker	NOUN
ajst-25630	12	22	in	in	ADP
ajst-25630	12	23	personalized	personalized	ADJ
ajst-25630	12	24	medicine	medicine	NOUN
ajst-25630	12	25	,	,	PUNCT
ajst-25630	12	26	thereby	thereby	ADV
ajst-25630	12	27	paving	pave	VERB
ajst-25630	12	28	new	new	ADJ
ajst-25630	12	29	paths	path	NOUN
ajst-25630	12	30	for	for	ADP
ajst-25630	12	31	precise	precise	ADJ
ajst-25630	12	32	diagnosis	diagnosis	NOUN
ajst-25630	12	33	and	and	CCONJ
ajst-25630	12	34	treatment	treatment	NOUN
ajst-25630	12	35	of	of	ADP
ajst-25630	12	36	kidney	kidney	NOUN
ajst-25630	12	37	diseases	disease	NOUN
ajst-25630	12	38	.	.	PUNCT
ajst-25630	13	1	keywords	keyword	NOUN
ajst-25630	13	2	:	:	PUNCT
ajst-25630	13	3	kidney	kidney	NOUN
ajst-25630	13	4	disease	disease	NOUN
ajst-25630	13	5	;	;	PUNCT
ajst-25630	13	6	biomarkers	biomarker	NOUN
ajst-25630	13	7	;	;	PUNCT
ajst-25630	13	8	early	early	ADJ
ajst-25630	13	9	diagnosis	diagnosis	NOUN
ajst-25630	13	10	;	;	PUNCT
ajst-25630	13	11	disease	disease	NOUN
ajst-25630	13	12	monitoring	monitoring	NOUN
ajst-25630	13	13	;	;	PUNCT
ajst-25630	13	14	personalized	personalized	ADJ
ajst-25630	13	15	medicine	medicine	NOUN
ajst-25630	13	16	.	.	PUNCT
ajst-25630	14	1	1	1	X
ajst-25630	14	2	.	.	X
ajst-25630	14	3	introduction	introduction	NOUN
ajst-25630	14	4	kidney	kidney	NOUN
ajst-25630	14	5	diseases	disease	NOUN
ajst-25630	14	6	represent	represent	VERB
ajst-25630	14	7	a	a	DET
ajst-25630	14	8	serious	serious	ADJ
ajst-25630	14	9	threat	threat	NOUN
ajst-25630	14	10	to	to	ADP
ajst-25630	14	11	global	global	ADJ
ajst-25630	14	12	public	public	ADJ
ajst-25630	14	13	health	health	NOUN
ajst-25630	14	14	,	,	PUNCT
ajst-25630	14	15	with	with	ADP
ajst-25630	14	16	incidence	incidence	NOUN
ajst-25630	14	17	and	and	CCONJ
ajst-25630	14	18	mortality	mortality	NOUN
ajst-25630	14	19	rates	rate	NOUN
ajst-25630	14	20	rising	rise	VERB
ajst-25630	14	21	worldwide[1	worldwide[1	ADP
ajst-25630	14	22	]	]	PUNCT
ajst-25630	14	23	.	.	PUNCT
ajst-25630	15	1	the	the	DET
ajst-25630	15	2	world	world	PROPN
ajst-25630	15	3	health	health	PROPN
ajst-25630	15	4	organization	organization	NOUN
ajst-25630	15	5	estimates	estimate	VERB
ajst-25630	15	6	that	that	SCONJ
ajst-25630	15	7	chronic	chronic	ADJ
ajst-25630	15	8	kidney	kidney	NOUN
ajst-25630	15	9	disease	disease	NOUN
ajst-25630	15	10	(	(	PUNCT
ajst-25630	15	11	ckd	ckd	NOUN
ajst-25630	15	12	)	)	PUNCT
ajst-25630	15	13	affects	affect	VERB
ajst-25630	15	14	approximately	approximately	ADV
ajst-25630	15	15	10	10	NUM
ajst-25630	15	16	%	%	NOUN
ajst-25630	15	17	of	of	ADP
ajst-25630	15	18	the	the	DET
ajst-25630	15	19	global	global	ADJ
ajst-25630	15	20	population	population	NOUN
ajst-25630	15	21	,	,	PUNCT
ajst-25630	15	22	while	while	SCONJ
ajst-25630	15	23	acute	acute	ADJ
ajst-25630	15	24	kidney	kidney	NOUN
ajst-25630	15	25	injury	injury	NOUN
ajst-25630	15	26	(	(	PUNCT
ajst-25630	15	27	aki	aki	NOUN
ajst-25630	15	28	)	)	PUNCT
ajst-25630	15	29	occurs	occur	VERB
ajst-25630	15	30	in	in	ADP
ajst-25630	15	31	up	up	ADP
ajst-25630	15	32	to	to	PART
ajst-25630	15	33	20	20	NUM
ajst-25630	15	34	%	%	NOUN
ajst-25630	15	35	of	of	ADP
ajst-25630	15	36	hospitalized	hospitalize	VERB
ajst-25630	15	37	patients	patient	NOUN
ajst-25630	15	38	[	[	X
ajst-25630	15	39	2	2	NUM
ajst-25630	15	40	]	]	PUNCT
ajst-25630	15	41	.	.	PUNCT
ajst-25630	16	1	these	these	DET
ajst-25630	16	2	diseases	disease	NOUN
ajst-25630	16	3	not	not	PART
ajst-25630	16	4	only	only	ADV
ajst-25630	16	5	severely	severely	ADV
ajst-25630	16	6	impact	impact	NOUN
ajst-25630	16	7	patients	patient	NOUN
ajst-25630	16	8	'	'	PART
ajst-25630	16	9	quality	quality	NOUN
ajst-25630	16	10	of	of	ADP
ajst-25630	16	11	life	life	NOUN
ajst-25630	16	12	but	but	CCONJ
ajst-25630	16	13	also	also	ADV
ajst-25630	16	14	impose	impose	VERB
ajst-25630	16	15	a	a	DET
ajst-25630	16	16	substantial	substantial	ADJ
ajst-25630	16	17	economic	economic	ADJ
ajst-25630	16	18	burden	burden	NOUN
ajst-25630	16	19	on	on	ADP
ajst-25630	16	20	healthcare	healthcare	NOUN
ajst-25630	16	21	systems	system	NOUN
ajst-25630	16	22	.	.	PUNCT
ajst-25630	17	1	early	early	ADJ
ajst-25630	17	2	diagnosis	diagnosis	NOUN
ajst-25630	17	3	and	and	CCONJ
ajst-25630	17	4	accurate	accurate	ADJ
ajst-25630	17	5	monitoring	monitoring	NOUN
ajst-25630	17	6	play	play	VERB
ajst-25630	17	7	crucial	crucial	ADJ
ajst-25630	17	8	roles	role	NOUN
ajst-25630	17	9	in	in	ADP
ajst-25630	17	10	kidney	kidney	NOUN
ajst-25630	17	11	disease	disease	NOUN
ajst-25630	17	12	management	management	NOUN
ajst-25630	17	13	.	.	PUNCT
ajst-25630	18	1	traditionally	traditionally	ADV
ajst-25630	18	2	,	,	PUNCT
ajst-25630	18	3	clinicians	clinician	NOUN
ajst-25630	18	4	have	have	AUX
ajst-25630	18	5	primarily	primarily	ADV
ajst-25630	18	6	relied	rely	VERB
ajst-25630	18	7	on	on	ADP
ajst-25630	18	8	indicators	indicator	NOUN
ajst-25630	18	9	such	such	ADJ
ajst-25630	18	10	as	as	ADP
ajst-25630	18	11	serum	serum	NOUN
ajst-25630	18	12	creatinine	creatinine	NOUN
ajst-25630	18	13	,	,	PUNCT
ajst-25630	18	14	blood	blood	NOUN
ajst-25630	18	15	urea	urea	NOUN
ajst-25630	18	16	nitrogen	nitrogen	NOUN
ajst-25630	18	17	,	,	PUNCT
ajst-25630	18	18	and	and	CCONJ
ajst-25630	18	19	proteinuria	proteinuria	NOUN
ajst-25630	18	20	to	to	PART
ajst-25630	18	21	assess	assess	VERB
ajst-25630	18	22	kidney	kidney	NOUN
ajst-25630	18	23	function[3	function[3	PROPN
ajst-25630	18	24	]	]	PUNCT
ajst-25630	18	25	.	.	PUNCT
ajst-25630	19	1	however	however	ADV
ajst-25630	19	2	,	,	PUNCT
ajst-25630	19	3	these	these	DET
ajst-25630	19	4	markers	marker	NOUN
ajst-25630	19	5	have	have	VERB
ajst-25630	19	6	significant	significant	ADJ
ajst-25630	19	7	limitations	limitation	NOUN
ajst-25630	19	8	:	:	PUNCT
ajst-25630	19	9	they	they	PRON
ajst-25630	19	10	often	often	ADV
ajst-25630	19	11	show	show	VERB
ajst-25630	19	12	abnormalities	abnormality	NOUN
ajst-25630	19	13	only	only	ADV
ajst-25630	19	14	after	after	ADP
ajst-25630	19	15	substantial	substantial	ADJ
ajst-25630	19	16	kidney	kidney	NOUN
ajst-25630	19	17	function	function	NOUN
ajst-25630	19	18	impairment	impairment	NOUN
ajst-25630	19	19	,	,	PUNCT
ajst-25630	19	20	failing	fail	VERB
ajst-25630	19	21	to	to	PART
ajst-25630	19	22	reflect	reflect	VERB
ajst-25630	19	23	early	early	ADJ
ajst-25630	19	24	or	or	CCONJ
ajst-25630	19	25	mild	mild	ADJ
ajst-25630	19	26	kidney	kidney	NOUN
ajst-25630	19	27	injury	injury	NOUN
ajst-25630	19	28	[	[	X
ajst-25630	19	29	4	4	NUM
ajst-25630	19	30	]	]	PUNCT
ajst-25630	19	31	.	.	PUNCT
ajst-25630	20	1	for	for	ADP
ajst-25630	20	2	instance	instance	NOUN
ajst-25630	20	3	,	,	PUNCT
ajst-25630	20	4	serum	serum	PROPN
ajst-25630	20	5	creatinine	creatinine	NOUN
ajst-25630	20	6	levels	level	NOUN
ajst-25630	20	7	only	only	ADV
ajst-25630	20	8	rise	rise	VERB
ajst-25630	20	9	significantly	significantly	ADV
ajst-25630	20	10	when	when	SCONJ
ajst-25630	20	11	glomerular	glomerular	ADJ
ajst-25630	20	12	filtration	filtration	NOUN
ajst-25630	20	13	rate	rate	NOUN
ajst-25630	20	14	decreases	decrease	NOUN
ajst-25630	20	15	by	by	ADP
ajst-25630	20	16	more	more	ADJ
ajst-25630	20	17	than	than	ADP
ajst-25630	20	18	50	50	NUM
ajst-25630	20	19	%	%	NOUN
ajst-25630	20	20	[	[	X
ajst-25630	20	21	5	5	NUM
ajst-25630	20	22	]	]	PUNCT
ajst-25630	20	23	.	.	PUNCT
ajst-25630	21	1	this	this	DET
ajst-25630	21	2	lag	lag	NOUN
ajst-25630	21	3	may	may	AUX
ajst-25630	21	4	result	result	VERB
ajst-25630	21	5	in	in	ADP
ajst-25630	21	6	missed	miss	VERB
ajst-25630	21	7	opportunities	opportunity	NOUN
ajst-25630	21	8	for	for	ADP
ajst-25630	21	9	optimal	optimal	ADJ
ajst-25630	21	10	treatment	treatment	NOUN
ajst-25630	21	11	,	,	PUNCT
ajst-25630	21	12	affecting	affect	VERB
ajst-25630	21	13	patient	patient	ADJ
ajst-25630	21	14	prognosis	prognosis	NOUN
ajst-25630	21	15	.	.	PUNCT
ajst-25630	22	1	in	in	ADP
ajst-25630	22	2	recent	recent	ADJ
ajst-25630	22	3	years	year	NOUN
ajst-25630	22	4	,	,	PUNCT
ajst-25630	22	5	with	with	ADP
ajst-25630	22	6	the	the	DET
ajst-25630	22	7	rapid	rapid	ADJ
ajst-25630	22	8	development	development	NOUN
ajst-25630	22	9	of	of	ADP
ajst-25630	22	10	molecular	molecular	ADJ
ajst-25630	22	11	biology	biology	NOUN
ajst-25630	22	12	,	,	PUNCT
ajst-25630	22	13	proteomics	proteomic	NOUN
ajst-25630	22	14	,	,	PUNCT
ajst-25630	22	15	and	and	CCONJ
ajst-25630	22	16	metabolomics	metabolomic	NOUN
ajst-25630	22	17	,	,	PUNCT
ajst-25630	22	18	a	a	DET
ajst-25630	22	19	series	series	NOUN
ajst-25630	22	20	of	of	ADP
ajst-25630	22	21	novel	novel	ADJ
ajst-25630	22	22	biomarkers	biomarker	NOUN
ajst-25630	22	23	have	have	AUX
ajst-25630	22	24	been	be	AUX
ajst-25630	22	25	discovered	discover	VERB
ajst-25630	22	26	and	and	CCONJ
ajst-25630	22	27	are	be	AUX
ajst-25630	22	28	gradually	gradually	ADV
ajst-25630	22	29	being	be	AUX
ajst-25630	22	30	applied	apply	VERB
ajst-25630	22	31	in	in	ADP
ajst-25630	22	32	clinical	clinical	ADJ
ajst-25630	22	33	practice[6	practice[6	NOUN
ajst-25630	22	34	]	]	PUNCT
ajst-25630	22	35	.	.	PUNCT
ajst-25630	23	1	these	these	DET
ajst-25630	23	2	new	new	ADJ
ajst-25630	23	3	markers	marker	NOUN
ajst-25630	23	4	not	not	PART
ajst-25630	23	5	only	only	ADV
ajst-25630	23	6	reflect	reflect	VERB
ajst-25630	23	7	kidney	kidney	NOUN
ajst-25630	23	8	injury	injury	NOUN
ajst-25630	23	9	earlier	early	ADV
ajst-25630	23	10	and	and	CCONJ
ajst-25630	23	11	more	more	ADV
ajst-25630	23	12	accurately	accurately	ADV
ajst-25630	23	13	but	but	CCONJ
ajst-25630	23	14	may	may	AUX
ajst-25630	23	15	also	also	ADV
ajst-25630	23	16	provide	provide	VERB
ajst-25630	23	17	important	important	ADJ
ajst-25630	23	18	bases	basis	NOUN
ajst-25630	23	19	for	for	ADP
ajst-25630	23	20	kidney	kidney	NOUN
ajst-25630	23	21	disease	disease	NOUN
ajst-25630	23	22	classification	classification	NOUN
ajst-25630	23	23	,	,	PUNCT
ajst-25630	23	24	severity	severity	NOUN
ajst-25630	23	25	assessment	assessment	NOUN
ajst-25630	23	26	,	,	PUNCT
ajst-25630	23	27	and	and	CCONJ
ajst-25630	23	28	prognosis	prognosis	NOUN
ajst-25630	23	29	prediction	prediction	NOUN
ajst-25630	23	30	[	[	X
ajst-25630	23	31	7	7	NUM
ajst-25630	23	32	]	]	PUNCT
ajst-25630	23	33	.	.	PUNCT
ajst-25630	24	1	for	for	ADP
ajst-25630	24	2	example	example	NOUN
ajst-25630	24	3	,	,	PUNCT
ajst-25630	24	4	neutrophil	neutrophil	ADJ
ajst-25630	24	5	gelatinase	gelatinase	NOUN
ajst-25630	24	6	-	-	PUNCT
ajst-25630	24	7	associated	associate	VERB
ajst-25630	24	8	lipocalin	lipocalin	NOUN
ajst-25630	24	9	(	(	PUNCT
ajst-25630	24	10	ngal	ngal	ADJ
ajst-25630	24	11	)	)	PUNCT
ajst-25630	24	12	and	and	CCONJ
ajst-25630	24	13	kidney	kidney	PROPN
ajst-25630	24	14	injury	injury	PROPN
ajst-25630	24	15	molecule-1	molecule-1	PROPN
ajst-25630	24	16	(	(	PUNCT
ajst-25630	24	17	kim-1	kim-1	X
ajst-25630	24	18	)	)	PUNCT
ajst-25630	24	19	can	can	AUX
ajst-25630	24	20	be	be	AUX
ajst-25630	24	21	detected	detect	VERB
ajst-25630	24	22	within	within	ADP
ajst-25630	24	23	hours	hour	NOUN
ajst-25630	24	24	of	of	ADP
ajst-25630	24	25	acute	acute	ADJ
ajst-25630	24	26	kidney	kidney	NOUN
ajst-25630	24	27	injury	injury	NOUN
ajst-25630	24	28	onset	onset	NOUN
ajst-25630	24	29	,	,	PUNCT
ajst-25630	24	30	days	day	NOUN
ajst-25630	24	31	ahead	ahead	ADV
ajst-25630	24	32	of	of	ADP
ajst-25630	24	33	traditional	traditional	ADJ
ajst-25630	24	34	markers	marker	NOUN
ajst-25630	24	35	[	[	X
ajst-25630	24	36	8	8	NUM
ajst-25630	24	37	]	]	PUNCT
ajst-25630	24	38	.	.	PUNCT
ajst-25630	25	1	however	however	ADV
ajst-25630	25	2	,	,	PUNCT
ajst-25630	25	3	these	these	DET
ajst-25630	25	4	novel	novel	ADJ
ajst-25630	25	5	markers	marker	NOUN
ajst-25630	25	6	still	still	ADV
ajst-25630	25	7	face	face	VERB
ajst-25630	25	8	challenges	challenge	NOUN
ajst-25630	25	9	such	such	ADJ
ajst-25630	25	10	as	as	ADP
ajst-25630	25	11	standardization	standardization	NOUN
ajst-25630	25	12	,	,	PUNCT
ajst-25630	25	13	cost	cost	NOUN
ajst-25630	25	14	-	-	PUNCT
ajst-25630	25	15	effectiveness	effectiveness	NOUN
ajst-25630	25	16	,	,	PUNCT
ajst-25630	25	17	and	and	CCONJ
ajst-25630	25	18	clinical	clinical	ADJ
ajst-25630	25	19	interpretation	interpretation	NOUN
ajst-25630	25	20	before	before	ADP
ajst-25630	25	21	widespread	widespread	ADJ
ajst-25630	25	22	clinical	clinical	ADJ
ajst-25630	25	23	application	application	NOUN
ajst-25630	25	24	.	.	PUNCT
ajst-25630	26	1	moreover	moreover	ADV
ajst-25630	26	2	,	,	PUNCT
ajst-25630	26	3	due	due	ADP
ajst-25630	26	4	to	to	ADP
ajst-25630	26	5	the	the	DET
ajst-25630	26	6	complexity	complexity	NOUN
ajst-25630	26	7	and	and	CCONJ
ajst-25630	26	8	heterogeneity	heterogeneity	NOUN
ajst-25630	26	9	of	of	ADP
ajst-25630	26	10	kidney	kidney	NOUN
ajst-25630	26	11	diseases	disease	NOUN
ajst-25630	26	12	,	,	PUNCT
ajst-25630	26	13	a	a	DET
ajst-25630	26	14	single	single	ADJ
ajst-25630	26	15	marker	marker	NOUN
ajst-25630	26	16	may	may	AUX
ajst-25630	26	17	struggle	struggle	VERB
ajst-25630	26	18	to	to	PART
ajst-25630	26	19	comprehensively	comprehensively	ADV
ajst-25630	26	20	reflect	reflect	VERB
ajst-25630	26	21	disease	disease	NOUN
ajst-25630	26	22	status	status	NOUN
ajst-25630	26	23	,	,	PUNCT
ajst-25630	26	24	leading	lead	VERB
ajst-25630	26	25	to	to	ADP
ajst-25630	26	26	increased	increase	VERB
ajst-25630	26	27	attention	attention	NOUN
ajst-25630	26	28	on	on	ADP
ajst-25630	26	29	multi	multi	ADJ
ajst-25630	26	30	-	-	NOUN
ajst-25630	26	31	marker	marker	NOUN
ajst-25630	26	32	combined	combine	VERB
ajst-25630	26	33	detection	detection	NOUN
ajst-25630	26	34	strategies[9	strategies[9	NOUN
ajst-25630	26	35	]	]	PUNCT
ajst-25630	26	36	.	.	PUNCT
ajst-25630	27	1	this	this	DET
ajst-25630	27	2	review	review	NOUN
ajst-25630	27	3	aims	aim	VERB
ajst-25630	27	4	to	to	PART
ajst-25630	27	5	summarize	summarize	VERB
ajst-25630	27	6	recent	recent	ADJ
ajst-25630	27	7	important	important	ADJ
ajst-25630	27	8	advances	advance	NOUN
ajst-25630	27	9	in	in	ADP
ajst-25630	27	10	kidney	kidney	NOUN
ajst-25630	27	11	disease	disease	NOUN
ajst-25630	27	12	biomarker	biomarker	NOUN
ajst-25630	27	13	research	research	NOUN
ajst-25630	27	14	,	,	PUNCT
ajst-25630	27	15	focusing	focus	VERB
ajst-25630	27	16	on	on	ADP
ajst-25630	27	17	several	several	ADJ
ajst-25630	27	18	representative	representative	ADJ
ajst-25630	27	19	novel	novel	NOUN
ajst-25630	27	20	markers	marker	NOUN
ajst-25630	27	21	.	.	PUNCT
ajst-25630	28	1	we	we	PRON
ajst-25630	28	2	will	will	AUX
ajst-25630	28	3	discuss	discuss	VERB
ajst-25630	28	4	their	their	PRON
ajst-25630	28	5	application	application	NOUN
ajst-25630	28	6	prospects	prospect	NOUN
ajst-25630	28	7	in	in	ADP
ajst-25630	28	8	early	early	ADJ
ajst-25630	28	9	diagnosis	diagnosis	NOUN
ajst-25630	28	10	and	and	CCONJ
ajst-25630	28	11	disease	disease	NOUN
ajst-25630	28	12	monitoring	monitoring	NOUN
ajst-25630	28	13	,	,	PUNCT
ajst-25630	28	14	and	and	CCONJ
ajst-25630	28	15	explore	explore	VERB
ajst-25630	28	16	the	the	DET
ajst-25630	28	17	potential	potential	ADJ
ajst-25630	28	18	advantages	advantage	NOUN
ajst-25630	28	19	of	of	ADP
ajst-25630	28	20	multimarker	multimarker	ADJ
ajst-25630	28	21	combined	combined	ADJ
ajst-25630	28	22	detection	detection	NOUN
ajst-25630	28	23	strategies	strategy	NOUN
ajst-25630	28	24	.	.	PUNCT
ajst-25630	29	1	simultaneously	simultaneously	ADV
ajst-25630	29	2	,	,	PUNCT
ajst-25630	29	3	we	we	PRON
ajst-25630	29	4	will	will	AUX
ajst-25630	29	5	analyze	analyze	VERB
ajst-25630	29	6	the	the	DET
ajst-25630	29	7	limitations	limitation	NOUN
ajst-25630	29	8	in	in	ADP
ajst-25630	29	9	current	current	ADJ
ajst-25630	29	10	research	research	NOUN
ajst-25630	29	11	and	and	CCONJ
ajst-25630	29	12	future	future	ADJ
ajst-25630	29	13	development	development	NOUN
ajst-25630	29	14	directions	direction	NOUN
ajst-25630	29	15	,	,	PUNCT
ajst-25630	29	16	providing	provide	VERB
ajst-25630	29	17	new	new	ADJ
ajst-25630	29	18	insights	insight	NOUN
ajst-25630	29	19	for	for	ADP
ajst-25630	29	20	precise	precise	ADJ
ajst-25630	29	21	diagnosis	diagnosis	NOUN
ajst-25630	29	22	and	and	CCONJ
ajst-25630	29	23	treatment	treatment	NOUN
ajst-25630	29	24	of	of	ADP
ajst-25630	29	25	kidney	kidney	NOUN
ajst-25630	29	26	diseases	disease	NOUN
ajst-25630	29	27	.	.	PUNCT
ajst-25630	30	1	2	2	X
ajst-25630	30	2	.	.	X
ajst-25630	30	3	limitations	limitation	NOUN
ajst-25630	30	4	of	of	ADP
ajst-25630	30	5	traditional	traditional	ADJ
ajst-25630	30	6	kidney	kidney	NOUN
ajst-25630	30	7	disease	disease	NOUN
ajst-25630	30	8	markers	marker	NOUN
ajst-25630	30	9	in	in	ADP
ajst-25630	30	10	clinical	clinical	ADJ
ajst-25630	30	11	practice	practice	NOUN
ajst-25630	30	12	of	of	ADP
ajst-25630	30	13	kidney	kidney	NOUN
ajst-25630	30	14	disease	disease	NOUN
ajst-25630	30	15	diagnosis	diagnosis	NOUN
ajst-25630	30	16	and	and	CCONJ
ajst-25630	30	17	monitoring	monitoring	NOUN
ajst-25630	30	18	,	,	PUNCT
ajst-25630	30	19	traditional	traditional	ADJ
ajst-25630	30	20	markers	marker	NOUN
ajst-25630	30	21	such	such	ADJ
ajst-25630	30	22	as	as	ADP
ajst-25630	30	23	serum	serum	NOUN
ajst-25630	30	24	creatinine	creatinine	NOUN
ajst-25630	30	25	(	(	PUNCT
ajst-25630	30	26	scr	scr	NOUN
ajst-25630	30	27	)	)	PUNCT
ajst-25630	30	28	,	,	PUNCT
ajst-25630	30	29	blood	blood	NOUN
ajst-25630	30	30	urea	urea	NOUN
ajst-25630	30	31	nitrogen	nitrogen	PROPN
ajst-25630	30	32	(	(	PUNCT
ajst-25630	30	33	bun	bun	PROPN
ajst-25630	30	34	)	)	PUNCT
ajst-25630	30	35	,	,	PUNCT
ajst-25630	30	36	proteinuria	proteinuria	NOUN
ajst-25630	30	37	,	,	PUNCT
ajst-25630	30	38	and	and	CCONJ
ajst-25630	30	39	estimated	estimate	VERB
ajst-25630	30	40	glomerular	glomerular	ADJ
ajst-25630	30	41	filtration	filtration	NOUN
ajst-25630	30	42	rate	rate	NOUN
ajst-25630	30	43	(	(	PUNCT
ajst-25630	30	44	egfr	egfr	X
ajst-25630	30	45	)	)	PUNCT
ajst-25630	30	46	have	have	AUX
ajst-25630	30	47	long	long	ADV
ajst-25630	30	48	played	play	VERB
ajst-25630	30	49	important	important	ADJ
ajst-25630	30	50	roles	role	NOUN
ajst-25630	30	51	.	.	PUNCT
ajst-25630	31	1	these	these	DET
ajst-25630	31	2	indicators	indicator	NOUN
ajst-25630	31	3	are	be	AUX
ajst-25630	31	4	widely	widely	ADV
ajst-25630	31	5	used	use	VERB
ajst-25630	31	6	due	due	ADP
ajst-25630	31	7	to	to	ADP
ajst-25630	31	8	their	their	PRON
ajst-25630	31	9	simple	simple	ADJ
ajst-25630	31	10	detection	detection	NOUN
ajst-25630	31	11	and	and	CCONJ
ajst-25630	31	12	low	low	ADJ
ajst-25630	31	13	cost	cost	NOUN
ajst-25630	31	14	,	,	PUNCT
ajst-25630	31	15	but	but	CCONJ
ajst-25630	31	16	they	they	PRON
ajst-25630	31	17	show	show	VERB
ajst-25630	31	18	significant	significant	ADJ
ajst-25630	31	19	deficiencies	deficiency	NOUN
ajst-25630	31	20	in	in	ADP
ajst-25630	31	21	early	early	ADJ
ajst-25630	31	22	diagnosis	diagnosis	NOUN
ajst-25630	31	23	and	and	CCONJ
ajst-25630	31	24	precise	precise	ADJ
ajst-25630	31	25	assessment	assessment	NOUN
ajst-25630	31	26	of	of	ADP
ajst-25630	31	27	kidney	kidney	NOUN
ajst-25630	31	28	injury	injury	NOUN
ajst-25630	31	29	.	.	PUNCT
ajst-25630	32	1	serum	serum	NOUN
ajst-25630	32	2	creatinine	creatinine	NOUN
ajst-25630	32	3	,	,	PUNCT
ajst-25630	32	4	as	as	ADP
ajst-25630	32	5	the	the	DET
ajst-25630	32	6	most	most	ADV
ajst-25630	32	7	commonly	commonly	ADV
ajst-25630	32	8	used	use	VERB
ajst-25630	32	9	indicator	indicator	NOUN
ajst-25630	32	10	for	for	ADP
ajst-25630	32	11	assessing	assess	VERB
ajst-25630	32	12	kidney	kidney	NOUN
ajst-25630	32	13	function	function	NOUN
ajst-25630	32	14	,	,	PUNCT
ajst-25630	32	15	primarily	primarily	ADV
ajst-25630	32	16	reflects	reflect	VERB
ajst-25630	32	17	glomerular	glomerular	ADJ
ajst-25630	32	18	filtration	filtration	NOUN
ajst-25630	32	19	function	function	NOUN
ajst-25630	32	20	.	.	PUNCT
ajst-25630	33	1	it	it	PRON
ajst-25630	33	2	is	be	AUX
ajst-25630	33	3	a	a	DET
ajst-25630	33	4	product	product	NOUN
ajst-25630	33	5	of	of	ADP
ajst-25630	33	6	muscle	muscle	NOUN
ajst-25630	33	7	metabolism	metabolism	NOUN
ajst-25630	33	8	,	,	PUNCT
ajst-25630	33	9	mainly	mainly	ADV
ajst-25630	33	10	excreted	excrete	VERB
ajst-25630	33	11	through	through	ADP
ajst-25630	33	12	glomerular	glomerular	ADJ
ajst-25630	33	13	filtration	filtration	NOUN
ajst-25630	33	14	.	.	PUNCT
ajst-25630	34	1	although	although	SCONJ
ajst-25630	34	2	scr	scr	NOUN
ajst-25630	34	3	correlates	correlate	VERB
ajst-25630	34	4	well	well	ADV
ajst-25630	34	5	with	with	ADP
ajst-25630	34	6	glomerular	glomerular	ADJ
ajst-25630	34	7	filtration	filtration	NOUN
ajst-25630	34	8	rate	rate	NOUN
ajst-25630	34	9	,	,	PUNCT
ajst-25630	34	10	its	its	PRON
ajst-25630	34	11	levels	level	NOUN
ajst-25630	34	12	are	be	AUX
ajst-25630	34	13	influenced	influence	VERB
ajst-25630	34	14	by	by	ADP
ajst-25630	34	15	various	various	ADJ
ajst-25630	34	16	factors	factor	NOUN
ajst-25630	34	17	such	such	ADJ
ajst-25630	34	18	as	as	ADP
ajst-25630	34	19	age	age	NOUN
ajst-25630	34	20	,	,	PUNCT
ajst-25630	34	21	gender	gender	NOUN
ajst-25630	34	22	,	,	PUNCT
ajst-25630	34	23	and	and	CCONJ
ajst-25630	34	24	muscle	muscle	PROPN
ajst-25630	34	25	mass	mass	NOUN
ajst-25630	34	26	.	.	PUNCT
ajst-25630	35	1	more	more	ADV
ajst-25630	35	2	importantly	importantly	ADV
ajst-25630	35	3	,	,	PUNCT
ajst-25630	35	4	scr	scr	NOUN
ajst-25630	35	5	only	only	ADV
ajst-25630	35	6	rises	rise	VERB
ajst-25630	35	7	significantly	significantly	ADV
ajst-25630	35	8	when	when	SCONJ
ajst-25630	35	9	kidney	kidney	NOUN
ajst-25630	35	10	function	function	NOUN
ajst-25630	35	11	is	be	AUX
ajst-25630	35	12	impaired	impair	VERB
ajst-25630	35	13	by	by	ADP
ajst-25630	35	14	more	more	ADJ
ajst-25630	35	15	than	than	ADP
ajst-25630	35	16	50	50	NUM
ajst-25630	35	17	%	%	NOUN
ajst-25630	35	18	,	,	PUNCT
ajst-25630	35	19	meaning	mean	VERB
ajst-25630	35	20	it	it	PRON
ajst-25630	35	21	can	can	AUX
ajst-25630	35	22	not	not	PART
ajst-25630	35	23	reflect	reflect	VERB
ajst-25630	35	24	early	early	ADJ
ajst-25630	35	25	kidney	kidney	NOUN
ajst-25630	35	26	injury	injury	NOUN
ajst-25630	35	27	[	[	X
ajst-25630	35	28	10	10	NUM
ajst-25630	35	29	]	]	PUNCT
ajst-25630	35	30	.	.	PUNCT
ajst-25630	36	1	in	in	ADP
ajst-25630	36	2	cases	case	NOUN
ajst-25630	36	3	of	of	ADP
ajst-25630	36	4	acute	acute	ADJ
ajst-25630	36	5	kidney	kidney	NOUN
ajst-25630	36	6	injury	injury	NOUN
ajst-25630	36	7	(	(	PUNCT
ajst-25630	36	8	aki	aki	NOUN
ajst-25630	36	9	)	)	PUNCT
ajst-25630	36	10	,	,	PUNCT
ajst-25630	36	11	changes	change	NOUN
ajst-25630	36	12	in	in	ADP
ajst-25630	36	13	scr	scr	NOUN
ajst-25630	36	14	may	may	AUX
ajst-25630	36	15	take	take	VERB
ajst-25630	36	16	24	24	NUM
ajst-25630	36	17	-	-	SYM
ajst-25630	36	18	48	48	NUM
ajst-25630	36	19	hours	hour	NOUN
ajst-25630	36	20	to	to	PART
ajst-25630	36	21	be	be	AUX
ajst-25630	36	22	detected	detect	VERB
ajst-25630	36	23	,	,	PUNCT
ajst-25630	36	24	and	and	CCONJ
ajst-25630	36	25	this	this	DET
ajst-25630	36	26	delay	delay	NOUN
ajst-25630	36	27	may	may	AUX
ajst-25630	36	28	result	result	VERB
ajst-25630	36	29	in	in	ADP
ajst-25630	36	30	missing	miss	VERB
ajst-25630	36	31	the	the	DET
ajst-25630	36	32	optimal	optimal	ADJ
ajst-25630	36	33	treatment	treatment	NOUN
ajst-25630	36	34	window	window	NOUN
ajst-25630	36	35	.	.	PUNCT
ajst-25630	37	1	218	218	NUM
ajst-25630	37	2	blood	blood	NOUN
ajst-25630	37	3	urea	urea	NOUN
ajst-25630	37	4	nitrogen	nitrogen	NOUN
ajst-25630	37	5	,	,	PUNCT
ajst-25630	37	6	as	as	ADP
ajst-25630	37	7	an	an	DET
ajst-25630	37	8	end	end	NOUN
ajst-25630	37	9	product	product	NOUN
ajst-25630	37	10	of	of	ADP
ajst-25630	37	11	protein	protein	NOUN
ajst-25630	37	12	metabolism	metabolism	NOUN
ajst-25630	37	13	,	,	PUNCT
ajst-25630	37	14	is	be	AUX
ajst-25630	37	15	also	also	ADV
ajst-25630	37	16	used	use	VERB
ajst-25630	37	17	to	to	PART
ajst-25630	37	18	assess	assess	VERB
ajst-25630	37	19	renal	renal	ADJ
ajst-25630	37	20	excretory	excretory	NOUN
ajst-25630	37	21	function	function	NOUN
ajst-25630	37	22	.	.	PUNCT
ajst-25630	38	1	however	however	ADV
ajst-25630	38	2	,	,	PUNCT
ajst-25630	38	3	bun	bun	PROPN
ajst-25630	38	4	levels	level	NOUN
ajst-25630	38	5	are	be	AUX
ajst-25630	38	6	not	not	PART
ajst-25630	38	7	only	only	ADV
ajst-25630	38	8	affected	affect	VERB
ajst-25630	38	9	by	by	ADP
ajst-25630	38	10	kidney	kidney	NOUN
ajst-25630	38	11	function	function	NOUN
ajst-25630	38	12	but	but	CCONJ
ajst-25630	38	13	also	also	ADV
ajst-25630	38	14	change	change	VERB
ajst-25630	38	15	due	due	ADJ
ajst-25630	38	16	to	to	ADP
ajst-25630	38	17	diet	diet	NOUN
ajst-25630	38	18	,	,	PUNCT
ajst-25630	38	19	liver	liver	NOUN
ajst-25630	38	20	function	function	NOUN
ajst-25630	38	21	,	,	PUNCT
ajst-25630	38	22	and	and	CCONJ
ajst-25630	38	23	the	the	DET
ajst-25630	38	24	use	use	NOUN
ajst-25630	38	25	of	of	ADP
ajst-25630	38	26	certain	certain	ADJ
ajst-25630	38	27	medications	medication	NOUN
ajst-25630	38	28	.	.	PUNCT
ajst-25630	39	1	these	these	DET
ajst-25630	39	2	multiple	multiple	ADJ
ajst-25630	39	3	influencing	influence	VERB
ajst-25630	39	4	factors	factor	NOUN
ajst-25630	39	5	reduce	reduce	VERB
ajst-25630	39	6	the	the	DET
ajst-25630	39	7	specificity	specificity	NOUN
ajst-25630	39	8	and	and	CCONJ
ajst-25630	39	9	sensitivity	sensitivity	NOUN
ajst-25630	39	10	of	of	ADP
ajst-25630	39	11	bun	bun	PROPN
ajst-25630	39	12	as	as	ADP
ajst-25630	39	13	a	a	DET
ajst-25630	39	14	kidney	kidney	NOUN
ajst-25630	39	15	function	function	NOUN
ajst-25630	39	16	indicator	indicator	NOUN
ajst-25630	39	17	.	.	PUNCT
ajst-25630	40	1	bun	bun	PROPN
ajst-25630	40	2	only	only	ADV
ajst-25630	40	3	rises	rise	VERB
ajst-25630	40	4	significantly	significantly	ADV
ajst-25630	40	5	when	when	SCONJ
ajst-25630	40	6	kidney	kidney	NOUN
ajst-25630	40	7	function	function	NOUN
ajst-25630	40	8	is	be	AUX
ajst-25630	40	9	severely	severely	ADV
ajst-25630	40	10	impaired	impair	VERB
ajst-25630	40	11	,	,	PUNCT
ajst-25630	40	12	limiting	limit	VERB
ajst-25630	40	13	its	its	PRON
ajst-25630	40	14	application	application	NOUN
ajst-25630	40	15	in	in	ADP
ajst-25630	40	16	early	early	ADJ
ajst-25630	40	17	diagnosis	diagnosis	NOUN
ajst-25630	40	18	.	.	PUNCT
ajst-25630	41	1	proteinuria	proteinuria	PROPN
ajst-25630	41	2	detection	detection	NOUN
ajst-25630	41	3	plays	play	VERB
ajst-25630	41	4	an	an	DET
ajst-25630	41	5	important	important	ADJ
ajst-25630	41	6	role	role	NOUN
ajst-25630	41	7	in	in	ADP
ajst-25630	41	8	assessing	assess	VERB
ajst-25630	41	9	glomerular	glomerular	ADJ
ajst-25630	41	10	filtration	filtration	NOUN
ajst-25630	41	11	membrane	membrane	NOUN
ajst-25630	41	12	integrity	integrity	NOUN
ajst-25630	41	13	,	,	PUNCT
ajst-25630	41	14	especially	especially	ADV
ajst-25630	41	15	in	in	ADP
ajst-25630	41	16	the	the	DET
ajst-25630	41	17	early	early	ADJ
ajst-25630	41	18	diagnosis	diagnosis	NOUN
ajst-25630	41	19	of	of	ADP
ajst-25630	41	20	certain	certain	ADJ
ajst-25630	41	21	kidney	kidney	NOUN
ajst-25630	41	22	diseases	disease	NOUN
ajst-25630	41	23	(	(	PUNCT
ajst-25630	41	24	such	such	ADJ
ajst-25630	41	25	as	as	ADP
ajst-25630	41	26	diabetic	diabetic	ADJ
ajst-25630	41	27	nephropathy	nephropathy	NOUN
ajst-25630	41	28	)	)	PUNCT
ajst-25630	41	29	.	.	PUNCT
ajst-25630	42	1	however	however	ADV
ajst-25630	42	2	,	,	PUNCT
ajst-25630	42	3	proteinuria	proteinuria	PROPN
ajst-25630	42	4	levels	level	NOUN
ajst-25630	42	5	can	can	AUX
ajst-25630	42	6	be	be	AUX
ajst-25630	42	7	affected	affect	VERB
ajst-25630	42	8	by	by	ADP
ajst-25630	42	9	various	various	ADJ
ajst-25630	42	10	temporary	temporary	ADJ
ajst-25630	42	11	factors	factor	NOUN
ajst-25630	42	12	(	(	PUNCT
ajst-25630	42	13	such	such	ADJ
ajst-25630	42	14	as	as	ADP
ajst-25630	42	15	intense	intense	ADJ
ajst-25630	42	16	exercise	exercise	NOUN
ajst-25630	42	17	,	,	PUNCT
ajst-25630	42	18	fever	fever	NOUN
ajst-25630	42	19	,	,	PUNCT
ajst-25630	42	20	etc	etc	X
ajst-25630	42	21	.	.	X
ajst-25630	42	22	)	)	PUNCT
ajst-25630	42	23	,	,	PUNCT
ajst-25630	42	24	and	and	CCONJ
ajst-25630	42	25	it	it	PRON
ajst-25630	42	26	can	can	AUX
ajst-25630	42	27	not	not	PART
ajst-25630	42	28	reflect	reflect	VERB
ajst-25630	42	29	changes	change	NOUN
ajst-25630	42	30	in	in	ADP
ajst-25630	42	31	tubular	tubular	ADJ
ajst-25630	42	32	function	function	NOUN
ajst-25630	42	33	.	.	PUNCT
ajst-25630	43	1	moreover	moreover	ADV
ajst-25630	43	2	,	,	PUNCT
ajst-25630	43	3	accurate	accurate	ADJ
ajst-25630	43	4	quantitative	quantitative	ADJ
ajst-25630	43	5	detection	detection	NOUN
ajst-25630	43	6	requires	require	VERB
ajst-25630	43	7	24	24	NUM
ajst-25630	43	8	-	-	PUNCT
ajst-25630	43	9	hour	hour	NOUN
ajst-25630	43	10	urine	urine	NOUN
ajst-25630	43	11	collection	collection	NOUN
ajst-25630	43	12	,	,	PUNCT
ajst-25630	43	13	and	and	CCONJ
ajst-25630	43	14	this	this	DET
ajst-25630	43	15	cumbersome	cumbersome	ADJ
ajst-25630	43	16	operation	operation	NOUN
ajst-25630	43	17	to	to	ADP
ajst-25630	43	18	some	some	DET
ajst-25630	43	19	extent	extent	NOUN
ajst-25630	43	20	limits	limit	VERB
ajst-25630	43	21	its	its	PRON
ajst-25630	43	22	clinical	clinical	ADJ
ajst-25630	43	23	application	application	NOUN
ajst-25630	43	24	.	.	PUNCT
ajst-25630	44	1	estimated	estimate	VERB
ajst-25630	44	2	glomerular	glomerular	ADJ
ajst-25630	44	3	filtration	filtration	NOUN
ajst-25630	44	4	rate	rate	NOUN
ajst-25630	44	5	(	(	PUNCT
ajst-25630	44	6	egfr	egfr	X
ajst-25630	44	7	)	)	PUNCT
ajst-25630	44	8	is	be	AUX
ajst-25630	44	9	a	a	DET
ajst-25630	44	10	comprehensive	comprehensive	ADJ
ajst-25630	44	11	indicator	indicator	NOUN
ajst-25630	44	12	calculated	calculate	VERB
ajst-25630	44	13	based	base	VERB
ajst-25630	44	14	on	on	ADP
ajst-25630	44	15	factors	factor	NOUN
ajst-25630	44	16	such	such	ADJ
ajst-25630	44	17	as	as	ADP
ajst-25630	44	18	serum	serum	NOUN
ajst-25630	44	19	creatinine	creatinine	NOUN
ajst-25630	44	20	,	,	PUNCT
ajst-25630	44	21	age	age	NOUN
ajst-25630	44	22	,	,	PUNCT
ajst-25630	44	23	and	and	CCONJ
ajst-25630	44	24	gender	gender	NOUN
ajst-25630	44	25	,	,	PUNCT
ajst-25630	44	26	which	which	PRON
ajst-25630	44	27	can	can	AUX
ajst-25630	44	28	more	more	ADV
ajst-25630	44	29	accurately	accurately	ADV
ajst-25630	44	30	assess	assess	VERB
ajst-25630	44	31	kidney	kidney	NOUN
ajst-25630	44	32	function	function	NOUN
ajst-25630	44	33	than	than	ADP
ajst-25630	44	34	using	use	VERB
ajst-25630	44	35	scr	scr	NOUN
ajst-25630	44	36	alone	alone	ADV
ajst-25630	44	37	.	.	PUNCT
ajst-25630	45	1	egfr	egfr	PROPN
ajst-25630	45	2	plays	play	VERB
ajst-25630	45	3	an	an	DET
ajst-25630	45	4	important	important	ADJ
ajst-25630	45	5	role	role	NOUN
ajst-25630	45	6	in	in	ADP
ajst-25630	45	7	the	the	DET
ajst-25630	45	8	staging	staging	NOUN
ajst-25630	45	9	and	and	CCONJ
ajst-25630	45	10	monitoring	monitoring	NOUN
ajst-25630	45	11	of	of	ADP
ajst-25630	45	12	chronic	chronic	ADJ
ajst-25630	45	13	kidney	kidney	NOUN
ajst-25630	45	14	disease	disease	NOUN
ajst-25630	45	15	(	(	PUNCT
ajst-25630	45	16	ckd	ckd	PROPN
ajst-25630	45	17	)	)	PUNCT
ajst-25630	45	18	.	.	PUNCT
ajst-25630	46	1	however	however	ADV
ajst-25630	46	2	,	,	PUNCT
ajst-25630	46	3	the	the	DET
ajst-25630	46	4	accuracy	accuracy	NOUN
ajst-25630	46	5	of	of	ADP
ajst-25630	46	6	egfr	egfr	NOUN
ajst-25630	46	7	may	may	AUX
ajst-25630	46	8	be	be	AUX
ajst-25630	46	9	affected	affect	VERB
ajst-25630	46	10	in	in	ADP
ajst-25630	46	11	certain	certain	ADJ
ajst-25630	46	12	special	special	ADJ
ajst-25630	46	13	populations	population	NOUN
ajst-25630	46	14	(	(	PUNCT
ajst-25630	46	15	such	such	ADJ
ajst-25630	46	16	as	as	ADP
ajst-25630	46	17	the	the	DET
ajst-25630	46	18	elderly	elderly	ADJ
ajst-25630	46	19	,	,	PUNCT
ajst-25630	46	20	extremely	extremely	ADV
ajst-25630	46	21	obese	obese	ADJ
ajst-25630	46	22	or	or	CCONJ
ajst-25630	46	23	thin	thin	ADJ
ajst-25630	46	24	individuals	individual	NOUN
ajst-25630	46	25	)	)	PUNCT
ajst-25630	46	26	.	.	PUNCT
ajst-25630	47	1	additionally	additionally	ADV
ajst-25630	47	2	,	,	PUNCT
ajst-25630	47	3	in	in	ADP
ajst-25630	47	4	the	the	DET
ajst-25630	47	5	early	early	ADJ
ajst-25630	47	6	stages	stage	NOUN
ajst-25630	47	7	of	of	ADP
ajst-25630	47	8	aki	aki	NOUN
ajst-25630	47	9	,	,	PUNCT
ajst-25630	47	10	egfr	egfr	NOUN
ajst-25630	47	11	may	may	AUX
ajst-25630	47	12	not	not	PART
ajst-25630	47	13	be	be	AUX
ajst-25630	47	14	sensitive	sensitive	ADJ
ajst-25630	47	15	enough	enough	ADV
ajst-25630	47	16	to	to	PART
ajst-25630	47	17	timely	timely	ADV
ajst-25630	47	18	reflect	reflect	VERB
ajst-25630	47	19	acute	acute	ADJ
ajst-25630	47	20	changes	change	NOUN
ajst-25630	47	21	in	in	ADP
ajst-25630	47	22	kidney	kidney	NOUN
ajst-25630	47	23	function	function	NOUN
ajst-25630	47	24	.	.	PUNCT
ajst-25630	48	1	these	these	DET
ajst-25630	48	2	limitations	limitation	NOUN
ajst-25630	48	3	of	of	ADP
ajst-25630	48	4	traditional	traditional	ADJ
ajst-25630	48	5	markers	marker	NOUN
ajst-25630	48	6	highlight	highlight	VERB
ajst-25630	48	7	the	the	DET
ajst-25630	48	8	necessity	necessity	NOUN
ajst-25630	48	9	of	of	ADP
ajst-25630	48	10	seeking	seek	VERB
ajst-25630	48	11	new	new	ADJ
ajst-25630	48	12	,	,	PUNCT
ajst-25630	48	13	more	more	ADV
ajst-25630	48	14	sensitive	sensitive	ADJ
ajst-25630	48	15	and	and	CCONJ
ajst-25630	48	16	specific	specific	ADJ
ajst-25630	48	17	biomarkers	biomarker	NOUN
ajst-25630	48	18	.	.	PUNCT
ajst-25630	49	1	ideal	ideal	ADJ
ajst-25630	49	2	kidney	kidney	NOUN
ajst-25630	49	3	disease	disease	NOUN
ajst-25630	49	4	biomarkers	biomarker	NOUN
ajst-25630	49	5	should	should	AUX
ajst-25630	49	6	have	have	VERB
ajst-25630	49	7	the	the	DET
ajst-25630	49	8	following	follow	VERB
ajst-25630	49	9	characteristics	characteristic	NOUN
ajst-25630	49	10	:	:	PUNCT
ajst-25630	49	11	ability	ability	NOUN
ajst-25630	49	12	to	to	PART
ajst-25630	49	13	reflect	reflect	VERB
ajst-25630	49	14	kidney	kidney	NOUN
ajst-25630	49	15	injury	injury	NOUN
ajst-25630	49	16	early	early	ADV
ajst-25630	49	17	,	,	PUNCT
ajst-25630	49	18	specificity	specificity	NOUN
ajst-25630	49	19	to	to	ADP
ajst-25630	49	20	the	the	DET
ajst-25630	49	21	kidney	kidney	NOUN
ajst-25630	49	22	,	,	PUNCT
ajst-25630	49	23	not	not	PART
ajst-25630	49	24	significantly	significantly	ADV
ajst-25630	49	25	affected	affect	VERB
ajst-25630	49	26	by	by	ADP
ajst-25630	49	27	other	other	ADJ
ajst-25630	49	28	organ	organ	NOUN
ajst-25630	49	29	functions	function	NOUN
ajst-25630	49	30	or	or	CCONJ
ajst-25630	49	31	external	external	ADJ
ajst-25630	49	32	factors	factor	NOUN
ajst-25630	49	33	,	,	PUNCT
ajst-25630	49	34	and	and	CCONJ
ajst-25630	49	35	ability	ability	NOUN
ajst-25630	49	36	to	to	PART
ajst-25630	49	37	accurately	accurately	ADV
ajst-25630	49	38	reflect	reflect	VERB
ajst-25630	49	39	disease	disease	NOUN
ajst-25630	49	40	severity	severity	NOUN
ajst-25630	49	41	and	and	CCONJ
ajst-25630	49	42	prognosis	prognosis	NOUN
ajst-25630	49	43	.	.	PUNCT
ajst-25630	50	1	3	3	X
ajst-25630	50	2	.	.	X
ajst-25630	50	3	novel	novel	ADJ
ajst-25630	50	4	kidney	kidney	NOUN
ajst-25630	50	5	disease	disease	NOUN
ajst-25630	50	6	biomarkers	biomarker	NOUN
ajst-25630	50	7	novel	novel	ADJ
ajst-25630	50	8	biomarkers	biomarker	NOUN
ajst-25630	50	9	not	not	PART
ajst-25630	50	10	only	only	ADV
ajst-25630	50	11	reflect	reflect	VERB
ajst-25630	50	12	kidney	kidney	NOUN
ajst-25630	50	13	injury	injury	NOUN
ajst-25630	50	14	earlier	early	ADV
ajst-25630	50	15	and	and	CCONJ
ajst-25630	50	16	more	more	ADV
ajst-25630	50	17	accurately	accurately	ADV
ajst-25630	50	18	but	but	CCONJ
ajst-25630	50	19	may	may	AUX
ajst-25630	50	20	also	also	ADV
ajst-25630	50	21	provide	provide	VERB
ajst-25630	50	22	important	important	ADJ
ajst-25630	50	23	bases	basis	NOUN
ajst-25630	50	24	for	for	ADP
ajst-25630	50	25	kidney	kidney	NOUN
ajst-25630	50	26	disease	disease	NOUN
ajst-25630	50	27	classification	classification	NOUN
ajst-25630	50	28	,	,	PUNCT
ajst-25630	50	29	severity	severity	NOUN
ajst-25630	50	30	assessment	assessment	NOUN
ajst-25630	50	31	,	,	PUNCT
ajst-25630	50	32	and	and	CCONJ
ajst-25630	50	33	prognosis	prognosis	NOUN
ajst-25630	50	34	prediction	prediction	NOUN
ajst-25630	50	35	.	.	PUNCT
ajst-25630	51	1	cystatin	cystatin	PROPN
ajst-25630	51	2	c	c	PROPN
ajst-25630	51	3	(	(	PUNCT
ajst-25630	51	4	cys	cys	PROPN
ajst-25630	51	5	-	-	PUNCT
ajst-25630	51	6	c	c	NOUN
ajst-25630	51	7	)	)	PUNCT
ajst-25630	51	8	is	be	AUX
ajst-25630	51	9	a	a	DET
ajst-25630	51	10	low	low	ADJ
ajst-25630	51	11	-	-	PUNCT
ajst-25630	51	12	molecular	molecular	ADJ
ajst-25630	51	13	-	-	PUNCT
ajst-25630	51	14	weight	weight	NOUN
ajst-25630	51	15	protein	protein	NOUN
ajst-25630	51	16	produced	produce	VERB
ajst-25630	51	17	by	by	ADP
ajst-25630	51	18	all	all	DET
ajst-25630	51	19	nucleated	nucleated	ADJ
ajst-25630	51	20	cells	cell	NOUN
ajst-25630	51	21	and	and	CCONJ
ajst-25630	51	22	freely	freely	ADV
ajst-25630	51	23	filtered	filter	VERB
ajst-25630	51	24	through	through	ADP
ajst-25630	51	25	the	the	DET
ajst-25630	51	26	glomeruli	glomeruli	NOUN
ajst-25630	51	27	.	.	PUNCT
ajst-25630	52	1	compared	compare	VERB
ajst-25630	52	2	to	to	ADP
ajst-25630	52	3	traditional	traditional	ADJ
ajst-25630	52	4	serum	serum	NOUN
ajst-25630	52	5	creatinine	creatinine	NOUN
ajst-25630	52	6	,	,	PUNCT
ajst-25630	52	7	cys	cys	PROPN
ajst-25630	52	8	-	-	PUNCT
ajst-25630	52	9	c	c	PROPN
ajst-25630	52	10	has	have	VERB
ajst-25630	52	11	significant	significant	ADJ
ajst-25630	52	12	advantages	advantage	NOUN
ajst-25630	52	13	.	.	PUNCT
ajst-25630	53	1	it	it	PRON
ajst-25630	53	2	is	be	AUX
ajst-25630	53	3	not	not	PART
ajst-25630	53	4	affected	affect	VERB
ajst-25630	53	5	by	by	ADP
ajst-25630	53	6	muscle	muscle	NOUN
ajst-25630	53	7	mass	mass	PROPN
ajst-25630	53	8	,	,	PUNCT
ajst-25630	53	9	age	age	NOUN
ajst-25630	53	10	,	,	PUNCT
ajst-25630	53	11	or	or	CCONJ
ajst-25630	53	12	gender	gender	NOUN
ajst-25630	53	13	,	,	PUNCT
ajst-25630	53	14	and	and	CCONJ
ajst-25630	53	15	is	be	AUX
ajst-25630	53	16	more	more	ADV
ajst-25630	53	17	sensitive	sensitive	ADJ
ajst-25630	53	18	to	to	ADP
ajst-25630	53	19	early	early	ADJ
ajst-25630	53	20	declines	decline	NOUN
ajst-25630	53	21	in	in	ADP
ajst-25630	53	22	kidney	kidney	NOUN
ajst-25630	53	23	function	function	NOUN
ajst-25630	53	24	[	[	X
ajst-25630	53	25	11	11	NUM
ajst-25630	53	26	]	]	PUNCT
ajst-25630	53	27	.	.	PUNCT
ajst-25630	54	1	cys	cys	PROPN
ajst-25630	54	2	-	-	PUNCT
ajst-25630	54	3	c	c	PROPN
ajst-25630	54	4	performs	perform	VERB
ajst-25630	54	5	better	well	ADV
ajst-25630	54	6	than	than	ADP
ajst-25630	54	7	serum	serum	NOUN
ajst-25630	54	8	creatinine	creatinine	NOUN
ajst-25630	54	9	,	,	PUNCT
ajst-25630	54	10	especially	especially	ADV
ajst-25630	54	11	in	in	ADP
ajst-25630	54	12	assessing	assess	VERB
ajst-25630	54	13	kidney	kidney	NOUN
ajst-25630	54	14	function	function	NOUN
ajst-25630	54	15	in	in	ADP
ajst-25630	54	16	the	the	DET
ajst-25630	54	17	elderly	elderly	ADJ
ajst-25630	54	18	.	.	PUNCT
ajst-25630	55	1	this	this	PRON
ajst-25630	55	2	makes	make	VERB
ajst-25630	55	3	cys	cys	PROPN
ajst-25630	55	4	-	-	PUNCT
ajst-25630	55	5	c	c	NOUN
ajst-25630	55	6	show	show	VERB
ajst-25630	55	7	unique	unique	ADJ
ajst-25630	55	8	value	value	NOUN
ajst-25630	55	9	in	in	ADP
ajst-25630	55	10	early	early	ADJ
ajst-25630	55	11	diagnosis	diagnosis	NOUN
ajst-25630	55	12	of	of	ADP
ajst-25630	55	13	chronic	chronic	ADJ
ajst-25630	55	14	kidney	kidney	NOUN
ajst-25630	55	15	disease	disease	NOUN
ajst-25630	55	16	(	(	PUNCT
ajst-25630	55	17	ckd	ckd	NOUN
ajst-25630	55	18	)	)	PUNCT
ajst-25630	55	19	and	and	CCONJ
ajst-25630	55	20	assessment	assessment	NOUN
ajst-25630	55	21	of	of	ADP
ajst-25630	55	22	cardiovascular	cardiovascular	ADJ
ajst-25630	55	23	disease	disease	NOUN
ajst-25630	55	24	risk	risk	NOUN
ajst-25630	55	25	.	.	PUNCT
ajst-25630	56	1	however	however	ADV
ajst-25630	56	2	,	,	PUNCT
ajst-25630	56	3	cys	cys	PROPN
ajst-25630	56	4	-	-	PUNCT
ajst-25630	56	5	c	c	PROPN
ajst-25630	56	6	levels	level	NOUN
ajst-25630	56	7	may	may	AUX
ajst-25630	56	8	be	be	AUX
ajst-25630	56	9	affected	affect	VERB
ajst-25630	56	10	by	by	ADP
ajst-25630	56	11	factors	factor	NOUN
ajst-25630	56	12	such	such	ADJ
ajst-25630	56	13	as	as	ADP
ajst-25630	56	14	thyroid	thyroid	NOUN
ajst-25630	56	15	function	function	NOUN
ajst-25630	56	16	and	and	CCONJ
ajst-25630	56	17	glucocorticoid	glucocorticoid	ADJ
ajst-25630	56	18	use	use	NOUN
ajst-25630	56	19	,	,	PUNCT
ajst-25630	56	20	which	which	PRON
ajst-25630	56	21	needs	need	VERB
ajst-25630	56	22	to	to	PART
ajst-25630	56	23	be	be	AUX
ajst-25630	56	24	considered	consider	VERB
ajst-25630	56	25	in	in	ADP
ajst-25630	56	26	clinical	clinical	ADJ
ajst-25630	56	27	interpretation	interpretation	NOUN
ajst-25630	56	28	.	.	PUNCT
ajst-25630	57	1	moreover	moreover	ADV
ajst-25630	57	2	,	,	PUNCT
ajst-25630	57	3	the	the	DET
ajst-25630	57	4	relatively	relatively	ADV
ajst-25630	57	5	high	high	ADJ
ajst-25630	57	6	detection	detection	NOUN
ajst-25630	57	7	cost	cost	NOUN
ajst-25630	57	8	also	also	ADV
ajst-25630	57	9	limits	limit	VERB
ajst-25630	57	10	its	its	PRON
ajst-25630	57	11	widespread	widespread	ADJ
ajst-25630	57	12	application	application	NOUN
ajst-25630	57	13	to	to	ADP
ajst-25630	57	14	some	some	DET
ajst-25630	57	15	extent	extent	NOUN
ajst-25630	57	16	.	.	PUNCT
ajst-25630	58	1	neutrophil	neutrophil	ADJ
ajst-25630	58	2	gelatinase	gelatinase	NOUN
ajst-25630	58	3	-	-	PUNCT
ajst-25630	58	4	associated	associate	VERB
ajst-25630	58	5	lipocalin	lipocalin	NOUN
ajst-25630	58	6	(	(	PUNCT
ajst-25630	58	7	ngal	ngal	ADJ
ajst-25630	58	8	)	)	PUNCT
ajst-25630	58	9	is	be	AUX
ajst-25630	58	10	another	another	DET
ajst-25630	58	11	novel	novel	ADJ
ajst-25630	58	12	marker	marker	NOUN
ajst-25630	58	13	receiving	receive	VERB
ajst-25630	58	14	much	much	ADJ
ajst-25630	58	15	attention	attention	NOUN
ajst-25630	58	16	.	.	PUNCT
ajst-25630	59	1	as	as	ADP
ajst-25630	59	2	an	an	DET
ajst-25630	59	3	acutephase	acutephase	ADJ
ajst-25630	59	4	protein	protein	NOUN
ajst-25630	59	5	,	,	PUNCT
ajst-25630	59	6	ngal	ngal	ADJ
ajst-25630	59	7	expression	expression	NOUN
ajst-25630	59	8	increases	increase	VERB
ajst-25630	59	9	significantly	significantly	ADV
ajst-25630	59	10	after	after	ADP
ajst-25630	59	11	tubular	tubular	ADJ
ajst-25630	59	12	injury	injury	NOUN
ajst-25630	59	13	.	.	PUNCT
ajst-25630	60	1	ngal	ngal	PROPN
ajst-25630	60	2	's	's	PART
ajst-25630	60	3	greatest	great	ADJ
ajst-25630	60	4	advantage	advantage	NOUN
ajst-25630	60	5	lies	lie	VERB
ajst-25630	60	6	in	in	ADP
ajst-25630	60	7	its	its	PRON
ajst-25630	60	8	rapid	rapid	ADJ
ajst-25630	60	9	responsiveness	responsiveness	NOUN
ajst-25630	60	10	:	:	PUNCT
ajst-25630	60	11	it	it	PRON
ajst-25630	60	12	can	can	AUX
ajst-25630	60	13	be	be	AUX
ajst-25630	60	14	detected	detect	VERB
ajst-25630	60	15	to	to	PART
ajst-25630	60	16	rise	rise	VERB
ajst-25630	60	17	within	within	ADP
ajst-25630	60	18	2	2	NUM
ajst-25630	60	19	-	-	SYM
ajst-25630	60	20	6	6	NUM
ajst-25630	60	21	hours	hour	NOUN
ajst-25630	60	22	after	after	SCONJ
ajst-25630	60	23	acute	acute	PROPN
ajst-25630	60	24	kidney	kidney	PROPN
ajst-25630	60	25	injury	injury	NOUN
ajst-25630	60	26	occurs	occur	VERB
ajst-25630	60	27	,	,	PUNCT
ajst-25630	60	28	which	which	PRON
ajst-25630	60	29	is	be	AUX
ajst-25630	60	30	24	24	NUM
ajst-25630	60	31	-	-	SYM
ajst-25630	60	32	48	48	NUM
ajst-25630	60	33	hours	hour	NOUN
ajst-25630	60	34	earlier	early	ADV
ajst-25630	60	35	than	than	ADP
ajst-25630	60	36	traditional	traditional	ADJ
ajst-25630	60	37	markers	marker	NOUN
ajst-25630	61	1	[	[	X
ajst-25630	61	2	12	12	NUM
ajst-25630	61	3	]	]	PUNCT
ajst-25630	61	4	.	.	PUNCT
ajst-25630	62	1	ngal	ngal	PROPN
ajst-25630	62	2	is	be	AUX
ajst-25630	62	3	highly	highly	ADV
ajst-25630	62	4	sensitive	sensitive	ADJ
ajst-25630	62	5	to	to	ADP
ajst-25630	62	6	ischemic	ischemic	ADJ
ajst-25630	62	7	and	and	CCONJ
ajst-25630	62	8	toxic	toxic	ADJ
ajst-25630	62	9	kidney	kidney	NOUN
ajst-25630	62	10	injury	injury	NOUN
ajst-25630	62	11	and	and	CCONJ
ajst-25630	62	12	can	can	AUX
ajst-25630	62	13	be	be	AUX
ajst-25630	62	14	detected	detect	VERB
ajst-25630	62	15	in	in	ADP
ajst-25630	62	16	urine	urine	NOUN
ajst-25630	62	17	and	and	CCONJ
ajst-25630	62	18	blood	blood	NOUN
ajst-25630	62	19	,	,	PUNCT
ajst-25630	62	20	giving	give	VERB
ajst-25630	62	21	it	it	PRON
ajst-25630	62	22	unique	unique	ADJ
ajst-25630	62	23	advantages	advantage	NOUN
ajst-25630	62	24	in	in	ADP
ajst-25630	62	25	early	early	ADJ
ajst-25630	62	26	diagnosis	diagnosis	NOUN
ajst-25630	62	27	of	of	ADP
ajst-25630	62	28	acute	acute	ADJ
ajst-25630	62	29	kidney	kidney	NOUN
ajst-25630	62	30	injury	injury	NOUN
ajst-25630	62	31	(	(	PUNCT
ajst-25630	62	32	aki	aki	NOUN
ajst-25630	62	33	)	)	PUNCT
ajst-25630	62	34	and	and	CCONJ
ajst-25630	62	35	predicting	predict	VERB
ajst-25630	62	36	aki	aki	NOUN
ajst-25630	62	37	severity	severity	NOUN
ajst-25630	62	38	.	.	PUNCT
ajst-25630	63	1	however	however	ADV
ajst-25630	63	2	,	,	PUNCT
ajst-25630	63	3	it	it	PRON
ajst-25630	63	4	should	should	AUX
ajst-25630	63	5	be	be	AUX
ajst-25630	63	6	noted	note	VERB
ajst-25630	63	7	that	that	SCONJ
ajst-25630	63	8	ngal	ngal	ADJ
ajst-25630	63	9	may	may	AUX
ajst-25630	63	10	also	also	ADV
ajst-25630	63	11	rise	rise	VERB
ajst-25630	63	12	in	in	ADP
ajst-25630	63	13	infection	infection	NOUN
ajst-25630	63	14	and	and	CCONJ
ajst-25630	63	15	inflammatory	inflammatory	ADJ
ajst-25630	63	16	states	state	NOUN
ajst-25630	63	17	,	,	PUNCT
ajst-25630	63	18	requiring	require	VERB
ajst-25630	63	19	consideration	consideration	NOUN
ajst-25630	63	20	of	of	ADP
ajst-25630	63	21	the	the	DET
ajst-25630	63	22	patient	patient	NOUN
ajst-25630	63	23	's	's	PART
ajst-25630	63	24	overall	overall	ADJ
ajst-25630	63	25	condition	condition	NOUN
ajst-25630	63	26	in	in	ADP
ajst-25630	63	27	clinical	clinical	ADJ
ajst-25630	63	28	interpretation	interpretation	NOUN
ajst-25630	63	29	.	.	PUNCT
ajst-25630	64	1	kidney	kidney	NOUN
ajst-25630	64	2	injury	injury	PROPN
ajst-25630	64	3	molecule-1	molecule-1	PROPN
ajst-25630	64	4	(	(	PUNCT
ajst-25630	64	5	kim-1	kim-1	X
ajst-25630	64	6	)	)	PUNCT
ajst-25630	64	7	is	be	AUX
ajst-25630	64	8	a	a	DET
ajst-25630	64	9	transmembrane	transmembrane	ADJ
ajst-25630	64	10	glycoprotein	glycoprotein	NOUN
ajst-25630	64	11	that	that	PRON
ajst-25630	64	12	is	be	AUX
ajst-25630	64	13	barely	barely	ADV
ajst-25630	64	14	expressed	express	VERB
ajst-25630	64	15	in	in	ADP
ajst-25630	64	16	normal	normal	ADJ
ajst-25630	64	17	kidneys	kidney	NOUN
ajst-25630	64	18	but	but	CCONJ
ajst-25630	64	19	significantly	significantly	ADV
ajst-25630	64	20	increases	increase	VERB
ajst-25630	64	21	in	in	ADP
ajst-25630	64	22	expression	expression	NOUN
ajst-25630	64	23	after	after	ADP
ajst-25630	64	24	tubular	tubular	ADJ
ajst-25630	64	25	epithelial	epithelial	ADJ
ajst-25630	64	26	cell	cell	NOUN
ajst-25630	64	27	injury	injury	NOUN
ajst-25630	64	28	.	.	PUNCT
ajst-25630	65	1	the	the	DET
ajst-25630	65	2	high	high	ADJ
ajst-25630	65	3	specificity	specificity	NOUN
ajst-25630	65	4	of	of	ADP
ajst-25630	65	5	kim-1	kim-1	NOUN
ajst-25630	65	6	makes	make	VERB
ajst-25630	65	7	it	it	PRON
ajst-25630	65	8	one	one	NUM
ajst-25630	65	9	of	of	ADP
ajst-25630	65	10	the	the	DET
ajst-25630	65	11	ideal	ideal	ADJ
ajst-25630	65	12	kidney	kidney	PROPN
ajst-25630	65	13	injury	injury	NOUN
ajst-25630	65	14	markers	marker	NOUN
ajst-25630	65	15	[	[	X
ajst-25630	65	16	13	13	NUM
ajst-25630	65	17	]	]	PUNCT
ajst-25630	65	18	.	.	PUNCT
ajst-25630	66	1	it	it	PRON
ajst-25630	66	2	is	be	AUX
ajst-25630	66	3	particularly	particularly	ADV
ajst-25630	66	4	sensitive	sensitive	ADJ
ajst-25630	66	5	to	to	ADP
ajst-25630	66	6	proximal	proximal	ADJ
ajst-25630	66	7	tubular	tubular	ADJ
ajst-25630	66	8	injury	injury	NOUN
ajst-25630	66	9	and	and	CCONJ
ajst-25630	66	10	can	can	AUX
ajst-25630	66	11	stably	stably	ADV
ajst-25630	66	12	exist	exist	VERB
ajst-25630	66	13	in	in	ADP
ajst-25630	66	14	urine	urine	NOUN
ajst-25630	66	15	,	,	PUNCT
ajst-25630	66	16	characteristics	characteristic	NOUN
ajst-25630	66	17	that	that	PRON
ajst-25630	66	18	make	make	VERB
ajst-25630	66	19	kim-1	kim-1	PUNCT
ajst-25630	66	20	perform	perform	VERB
ajst-25630	66	21	excellently	excellently	ADV
ajst-25630	66	22	in	in	ADP
ajst-25630	66	23	early	early	ADJ
ajst-25630	66	24	diagnosis	diagnosis	NOUN
ajst-25630	66	25	of	of	ADP
ajst-25630	66	26	acute	acute	ADJ
ajst-25630	66	27	tubular	tubular	ADJ
ajst-25630	66	28	necrosis	necrosis	NOUN
ajst-25630	66	29	and	and	CCONJ
ajst-25630	66	30	monitoring	monitor	VERB
ajst-25630	66	31	kidney	kidney	NOUN
ajst-25630	66	32	injury	injury	NOUN
ajst-25630	66	33	caused	cause	VERB
ajst-25630	66	34	by	by	ADP
ajst-25630	66	35	nephrotoxic	nephrotoxic	ADJ
ajst-25630	66	36	drugs	drug	NOUN
ajst-25630	66	37	.	.	PUNCT
ajst-25630	67	1	however	however	ADV
ajst-25630	67	2	,	,	PUNCT
ajst-25630	67	3	since	since	SCONJ
ajst-25630	67	4	kim-1	kim-1	VERB
ajst-25630	67	5	mainly	mainly	ADV
ajst-25630	67	6	reflects	reflect	VERB
ajst-25630	67	7	tubular	tubular	ADJ
ajst-25630	67	8	injury	injury	NOUN
ajst-25630	67	9	,	,	PUNCT
ajst-25630	67	10	its	its	PRON
ajst-25630	67	11	sensitivity	sensitivity	NOUN
ajst-25630	67	12	to	to	ADP
ajst-25630	67	13	glomerular	glomerular	ADJ
ajst-25630	67	14	diseases	disease	NOUN
ajst-25630	67	15	is	be	AUX
ajst-25630	67	16	relatively	relatively	ADV
ajst-25630	67	17	low	low	ADJ
ajst-25630	67	18	,	,	PUNCT
ajst-25630	67	19	which	which	PRON
ajst-25630	67	20	needs	need	VERB
ajst-25630	67	21	to	to	PART
ajst-25630	67	22	be	be	AUX
ajst-25630	67	23	noted	note	VERB
ajst-25630	67	24	in	in	ADP
ajst-25630	67	25	application	application	NOUN
ajst-25630	67	26	.	.	PUNCT
ajst-25630	68	1	liver	liver	NOUN
ajst-25630	68	2	-	-	PUNCT
ajst-25630	68	3	type	type	NOUN
ajst-25630	68	4	fatty	fatty	NOUN
ajst-25630	68	5	acid	acid	NOUN
ajst-25630	68	6	-	-	PUNCT
ajst-25630	68	7	binding	bind	VERB
ajst-25630	68	8	protein	protein	NOUN
ajst-25630	68	9	(	(	PUNCT
ajst-25630	68	10	l	l	NOUN
ajst-25630	68	11	-	-	PUNCT
ajst-25630	68	12	fabp	fabp	NOUN
ajst-25630	68	13	)	)	PUNCT
ajst-25630	68	14	is	be	AUX
ajst-25630	68	15	an	an	DET
ajst-25630	68	16	intracellular	intracellular	ADJ
ajst-25630	68	17	lipid	lipid	NOUN
ajst-25630	68	18	carrier	carrier	NOUN
ajst-25630	68	19	protein	protein	NOUN
ajst-25630	68	20	expressed	express	VERB
ajst-25630	68	21	in	in	ADP
ajst-25630	68	22	renal	renal	ADJ
ajst-25630	68	23	proximal	proximal	ADJ
ajst-25630	68	24	tubules	tubule	NOUN
ajst-25630	68	25	.	.	PUNCT
ajst-25630	69	1	l	l	NOUN
ajst-25630	69	2	-	-	PUNCT
ajst-25630	69	3	fabp	fabp	PROPN
ajst-25630	69	4	is	be	AUX
ajst-25630	69	5	highly	highly	ADV
ajst-25630	69	6	sensitive	sensitive	ADJ
ajst-25630	69	7	to	to	ADP
ajst-25630	69	8	hypoxia	hypoxia	NOUN
ajst-25630	69	9	and	and	CCONJ
ajst-25630	69	10	oxidative	oxidative	ADJ
ajst-25630	69	11	stress	stress	NOUN
ajst-25630	69	12	,	,	PUNCT
ajst-25630	69	13	with	with	ADP
ajst-25630	69	14	increased	increase	VERB
ajst-25630	69	15	expression	expression	NOUN
ajst-25630	69	16	in	in	ADP
ajst-25630	69	17	various	various	ADJ
ajst-25630	69	18	kidney	kidney	NOUN
ajst-25630	69	19	diseases[14	diseases[14	PROPN
ajst-25630	69	20	]	]	PUNCT
ajst-25630	69	21	.	.	PUNCT
ajst-25630	70	1	this	this	PRON
ajst-25630	70	2	makes	make	VERB
ajst-25630	70	3	l	l	NOUN
ajst-25630	70	4	-	-	NOUN
ajst-25630	70	5	fabp	fabp	VERB
ajst-25630	70	6	potentially	potentially	ADV
ajst-25630	70	7	valuable	valuable	ADJ
ajst-25630	70	8	in	in	ADP
ajst-25630	70	9	early	early	ADJ
ajst-25630	70	10	diagnosis	diagnosis	NOUN
ajst-25630	70	11	of	of	ADP
ajst-25630	70	12	acute	acute	ADJ
ajst-25630	70	13	kidney	kidney	NOUN
ajst-25630	70	14	injury	injury	NOUN
ajst-25630	70	15	and	and	CCONJ
ajst-25630	70	16	monitoring	monitor	VERB
ajst-25630	70	17	the	the	DET
ajst-25630	70	18	progression	progression	NOUN
ajst-25630	70	19	of	of	ADP
ajst-25630	70	20	chronic	chronic	ADJ
ajst-25630	70	21	kidney	kidney	NOUN
ajst-25630	70	22	disease	disease	NOUN
ajst-25630	70	23	.	.	PUNCT
ajst-25630	71	1	l	l	NOUN
ajst-25630	71	2	-	-	PUNCT
ajst-25630	71	3	fabp	fabp	PROPN
ajst-25630	71	4	can	can	AUX
ajst-25630	71	5	be	be	AUX
ajst-25630	71	6	detected	detect	VERB
ajst-25630	71	7	in	in	ADP
ajst-25630	71	8	urine	urine	NOUN
ajst-25630	71	9	,	,	PUNCT
ajst-25630	71	10	providing	provide	VERB
ajst-25630	71	11	the	the	DET
ajst-25630	71	12	possibility	possibility	NOUN
ajst-25630	71	13	for	for	ADP
ajst-25630	71	14	non	non	ADJ
ajst-25630	71	15	-	-	ADJ
ajst-25630	71	16	invasive	invasive	ADJ
ajst-25630	71	17	monitoring	monitoring	NOUN
ajst-25630	71	18	.	.	PUNCT
ajst-25630	72	1	however	however	ADV
ajst-25630	72	2	,	,	PUNCT
ajst-25630	72	3	l	l	ADJ
ajst-25630	72	4	-	-	ADJ
ajst-25630	72	5	fabp	fabp	ADJ
ajst-25630	72	6	levels	level	NOUN
ajst-25630	72	7	may	may	AUX
ajst-25630	72	8	also	also	ADV
ajst-25630	72	9	be	be	AUX
ajst-25630	72	10	affected	affect	VERB
ajst-25630	72	11	by	by	ADP
ajst-25630	72	12	liver	liver	NOUN
ajst-25630	72	13	disease	disease	NOUN
ajst-25630	72	14	,	,	PUNCT
ajst-25630	72	15	which	which	PRON
ajst-25630	72	16	needs	need	VERB
ajst-25630	72	17	to	to	PART
ajst-25630	72	18	be	be	AUX
ajst-25630	72	19	considered	consider	VERB
ajst-25630	72	20	in	in	ADP
ajst-25630	72	21	clinical	clinical	ADJ
ajst-25630	72	22	applications	application	NOUN
ajst-25630	72	23	.	.	PUNCT
ajst-25630	73	1	interleukin-18	interleukin-18	PROPN
ajst-25630	73	2	(	(	PUNCT
ajst-25630	73	3	il-18	il-18	PRON
ajst-25630	73	4	)	)	PUNCT
ajst-25630	73	5	is	be	AUX
ajst-25630	73	6	a	a	DET
ajst-25630	73	7	pro	pro	ADJ
ajst-25630	73	8	-	-	ADJ
ajst-25630	73	9	inflammatory	inflammatory	ADJ
ajst-25630	73	10	cytokine	cytokine	NOUN
ajst-25630	73	11	that	that	PRON
ajst-25630	73	12	increases	increase	VERB
ajst-25630	73	13	in	in	ADP
ajst-25630	73	14	release	release	NOUN
ajst-25630	73	15	after	after	ADP
ajst-25630	73	16	tubular	tubular	ADJ
ajst-25630	73	17	injury	injury	NOUN
ajst-25630	73	18	.	.	PUNCT
ajst-25630	74	1	il-18	il-18	PUNCT
ajst-25630	74	2	can	can	AUX
ajst-25630	74	3	be	be	AUX
ajst-25630	74	4	detected	detect	VERB
ajst-25630	74	5	to	to	PART
ajst-25630	74	6	rise	rise	VERB
ajst-25630	74	7	early	early	ADV
ajst-25630	74	8	after	after	SCONJ
ajst-25630	74	9	aki	aki	NOUN
ajst-25630	74	10	occurs	occur	VERB
ajst-25630	74	11	and	and	CCONJ
ajst-25630	74	12	is	be	AUX
ajst-25630	74	13	particularly	particularly	ADV
ajst-25630	74	14	sensitive	sensitive	ADJ
ajst-25630	74	15	to	to	ADP
ajst-25630	74	16	ischemic	ischemic	ADJ
ajst-25630	74	17	kidney	kidney	NOUN
ajst-25630	74	18	injury	injury	NOUN
ajst-25630	75	1	[	[	X
ajst-25630	75	2	15	15	NUM
ajst-25630	75	3	]	]	PUNCT
ajst-25630	75	4	.	.	PUNCT
ajst-25630	76	1	this	this	PRON
ajst-25630	76	2	gives	give	VERB
ajst-25630	76	3	il-18	il-18	PUNCT
ajst-25630	76	4	unique	unique	ADJ
ajst-25630	76	5	advantages	advantage	NOUN
ajst-25630	76	6	in	in	ADP
ajst-25630	76	7	early	early	ADJ
ajst-25630	76	8	diagnosis	diagnosis	NOUN
ajst-25630	76	9	and	and	CCONJ
ajst-25630	76	10	prediction	prediction	NOUN
ajst-25630	76	11	of	of	ADP
ajst-25630	76	12	acute	acute	ADJ
ajst-25630	76	13	kidney	kidney	NOUN
ajst-25630	76	14	injury	injury	NOUN
ajst-25630	76	15	,	,	PUNCT
ajst-25630	76	16	as	as	ADV
ajst-25630	76	17	well	well	ADV
ajst-25630	76	18	as	as	ADP
ajst-25630	76	19	assessment	assessment	NOUN
ajst-25630	76	20	of	of	ADP
ajst-25630	76	21	rejection	rejection	NOUN
ajst-25630	76	22	reactions	reaction	NOUN
ajst-25630	76	23	after	after	ADP
ajst-25630	76	24	kidney	kidney	NOUN
ajst-25630	76	25	transplantation	transplantation	NOUN
ajst-25630	76	26	.	.	PUNCT
ajst-25630	77	1	however	however	ADV
ajst-25630	77	2	,	,	PUNCT
ajst-25630	77	3	since	since	SCONJ
ajst-25630	77	4	il-18	il-18	PUNCT
ajst-25630	77	5	may	may	AUX
ajst-25630	77	6	also	also	ADV
ajst-25630	77	7	rise	rise	VERB
ajst-25630	77	8	in	in	ADP
ajst-25630	77	9	other	other	ADJ
ajst-25630	77	10	inflammatory	inflammatory	ADJ
ajst-25630	77	11	states	state	NOUN
ajst-25630	77	12	,	,	PUNCT
ajst-25630	77	13	its	its	PRON
ajst-25630	77	14	clinical	clinical	ADJ
ajst-25630	77	15	interpretation	interpretation	NOUN
ajst-25630	77	16	needs	need	VERB
ajst-25630	77	17	to	to	PART
ajst-25630	77	18	be	be	AUX
ajst-25630	77	19	combined	combine	VERB
ajst-25630	77	20	with	with	ADP
ajst-25630	77	21	the	the	DET
ajst-25630	77	22	patient	patient	NOUN
ajst-25630	77	23	's	's	PART
ajst-25630	77	24	overall	overall	ADJ
ajst-25630	77	25	condition	condition	NOUN
ajst-25630	77	26	.	.	PUNCT
ajst-25630	78	1	although	although	SCONJ
ajst-25630	78	2	novel	novel	ADJ
ajst-25630	78	3	biomarkers	biomarker	NOUN
ajst-25630	78	4	provide	provide	VERB
ajst-25630	78	5	new	new	ADJ
ajst-25630	78	6	tools	tool	NOUN
ajst-25630	78	7	for	for	ADP
ajst-25630	78	8	early	early	ADJ
ajst-25630	78	9	diagnosis	diagnosis	NOUN
ajst-25630	78	10	and	and	CCONJ
ajst-25630	78	11	precise	precise	ADJ
ajst-25630	78	12	monitoring	monitoring	NOUN
ajst-25630	78	13	of	of	ADP
ajst-25630	78	14	kidney	kidney	NOUN
ajst-25630	78	15	diseases	disease	NOUN
ajst-25630	78	16	,	,	PUNCT
ajst-25630	78	17	their	their	PRON
ajst-25630	78	18	clinical	clinical	ADJ
ajst-25630	78	19	application	application	NOUN
ajst-25630	78	20	still	still	ADV
ajst-25630	78	21	faces	face	VERB
ajst-25630	78	22	challenges	challenge	NOUN
ajst-25630	78	23	such	such	ADJ
ajst-25630	78	24	as	as	ADP
ajst-25630	78	25	standardization	standardization	NOUN
ajst-25630	78	26	,	,	PUNCT
ajst-25630	78	27	cost	cost	NOUN
ajst-25630	78	28	-	-	PUNCT
ajst-25630	78	29	effectiveness	effectiveness	NOUN
ajst-25630	78	30	,	,	PUNCT
ajst-25630	78	31	and	and	CCONJ
ajst-25630	78	32	large	large	ADJ
ajst-25630	78	33	-	-	PUNCT
ajst-25630	78	34	scale	scale	NOUN
ajst-25630	78	35	validation	validation	NOUN
ajst-25630	78	36	.	.	PUNCT
ajst-25630	79	1	future	future	ADJ
ajst-25630	79	2	research	research	NOUN
ajst-25630	79	3	needs	need	VERB
ajst-25630	79	4	to	to	PART
ajst-25630	79	5	further	far	ADV
ajst-25630	79	6	clarify	clarify	VERB
ajst-25630	79	7	the	the	DET
ajst-25630	79	8	performance	performance	NOUN
ajst-25630	79	9	characteristics	characteristic	NOUN
ajst-25630	79	10	of	of	ADP
ajst-25630	79	11	these	these	DET
ajst-25630	79	12	markers	marker	NOUN
ajst-25630	79	13	in	in	ADP
ajst-25630	79	14	different	different	ADJ
ajst-25630	79	15	types	type	NOUN
ajst-25630	79	16	and	and	CCONJ
ajst-25630	79	17	stages	stage	NOUN
ajst-25630	79	18	of	of	ADP
ajst-25630	79	19	kidney	kidney	NOUN
ajst-25630	79	20	diseases	disease	NOUN
ajst-25630	79	21	,	,	PUNCT
ajst-25630	79	22	establish	establish	VERB
ajst-25630	79	23	unified	unified	ADJ
ajst-25630	79	24	detection	detection	NOUN
ajst-25630	79	25	standards	standard	NOUN
ajst-25630	79	26	and	and	CCONJ
ajst-25630	79	27	reference	reference	NOUN
ajst-25630	79	28	ranges	range	VERB
ajst-25630	79	29	,	,	PUNCT
ajst-25630	79	30	and	and	CCONJ
ajst-25630	79	31	explore	explore	VERB
ajst-25630	79	32	their	their	PRON
ajst-25630	79	33	application	application	NOUN
ajst-25630	79	34	value	value	NOUN
ajst-25630	79	35	in	in	ADP
ajst-25630	79	36	personalized	personalized	ADJ
ajst-25630	79	37	medicine	medicine	NOUN
ajst-25630	79	38	.	.	PUNCT
ajst-25630	80	1	4	4	X
ajst-25630	80	2	.	.	X
ajst-25630	80	3	application	application	NOUN
ajst-25630	80	4	of	of	ADP
ajst-25630	80	5	novel	novel	ADJ
ajst-25630	80	6	markers	marker	NOUN
ajst-25630	80	7	in	in	ADP
ajst-25630	80	8	different	different	ADJ
ajst-25630	80	9	types	type	NOUN
ajst-25630	80	10	of	of	ADP
ajst-25630	80	11	kidney	kidney	NOUN
ajst-25630	80	12	diseases	disease	NOUN
ajst-25630	80	13	as	as	ADP
ajst-25630	80	14	research	research	NOUN
ajst-25630	80	15	on	on	ADP
ajst-25630	80	16	novel	novel	ADJ
ajst-25630	80	17	biomarkers	biomarker	NOUN
ajst-25630	80	18	deepens	deepen	VERB
ajst-25630	80	19	,	,	PUNCT
ajst-25630	80	20	their	their	PRON
ajst-25630	80	21	application	application	NOUN
ajst-25630	80	22	value	value	NOUN
ajst-25630	80	23	in	in	ADP
ajst-25630	80	24	various	various	ADJ
ajst-25630	80	25	kidney	kidney	NOUN
ajst-25630	80	26	diseases	disease	NOUN
ajst-25630	80	27	is	be	AUX
ajst-25630	80	28	gradually	gradually	ADV
ajst-25630	80	29	emerging	emerge	VERB
ajst-25630	80	30	.	.	PUNCT
ajst-25630	81	1	from	from	ADP
ajst-25630	81	2	acute	acute	PROPN
ajst-25630	81	3	kidney	kidney	NOUN
ajst-25630	81	4	injury	injury	NOUN
ajst-25630	81	5	to	to	ADP
ajst-25630	81	6	chronic	chronic	ADJ
ajst-25630	81	7	kidney	kidney	NOUN
ajst-25630	81	8	disease	disease	NOUN
ajst-25630	81	9	,	,	PUNCT
ajst-25630	81	10	from	from	ADP
ajst-25630	81	11	diabetic	diabetic	ADJ
ajst-25630	81	12	nephropathy	nephropathy	NOUN
ajst-25630	81	13	to	to	ADP
ajst-25630	81	14	kidney	kidney	NOUN
ajst-25630	81	15	transplantation	transplantation	NOUN
ajst-25630	81	16	,	,	PUNCT
ajst-25630	81	17	these	these	DET
ajst-25630	81	18	markers	marker	NOUN
ajst-25630	81	19	are	be	AUX
ajst-25630	81	20	changing	change	VERB
ajst-25630	81	21	our	our	PRON
ajst-25630	81	22	understanding	understanding	NOUN
ajst-25630	81	23	of	of	ADP
ajst-25630	81	24	kidney	kidney	NOUN
ajst-25630	81	25	disease	disease	NOUN
ajst-25630	81	26	diagnosis	diagnosis	NOUN
ajst-25630	81	27	and	and	CCONJ
ajst-25630	81	28	monitoring	monitoring	NOUN
ajst-25630	81	29	.	.	PUNCT
ajst-25630	82	1	in	in	ADP
ajst-25630	82	2	the	the	DET
ajst-25630	82	3	diagnosis	diagnosis	NOUN
ajst-25630	82	4	and	and	CCONJ
ajst-25630	82	5	management	management	NOUN
ajst-25630	82	6	of	of	ADP
ajst-25630	82	7	acute	acute	ADJ
ajst-25630	82	8	kidney	kidney	NOUN
ajst-25630	82	9	injury	injury	NOUN
ajst-25630	82	10	(	(	PUNCT
ajst-25630	82	11	aki	aki	NOUN
ajst-25630	82	12	)	)	PUNCT
ajst-25630	82	13	,	,	PUNCT
ajst-25630	82	14	novel	novel	ADJ
ajst-25630	82	15	biomarkers	biomarker	NOUN
ajst-25630	82	16	show	show	VERB
ajst-25630	82	17	significant	significant	ADJ
ajst-25630	82	18	advantages	advantage	NOUN
ajst-25630	82	19	.	.	PUNCT
ajst-25630	83	1	traditionally	traditionally	ADV
ajst-25630	83	2	,	,	PUNCT
ajst-25630	83	3	aki	aki	NOUN
ajst-25630	83	4	diagnosis	diagnosis	NOUN
ajst-25630	83	5	mainly	mainly	ADV
ajst-25630	83	6	relied	rely	VERB
ajst-25630	83	7	on	on	ADP
ajst-25630	83	8	the	the	DET
ajst-25630	83	9	rise	rise	NOUN
ajst-25630	83	10	of	of	ADP
ajst-25630	83	11	serum	serum	NOUN
ajst-25630	83	12	creatinine	creatinine	NOUN
ajst-25630	83	13	,	,	PUNCT
ajst-25630	83	14	but	but	CCONJ
ajst-25630	83	15	this	this	DET
ajst-25630	83	16	change	change	NOUN
ajst-25630	83	17	usually	usually	ADV
ajst-25630	83	18	lags	lag	VERB
ajst-25630	83	19	behind	behind	ADP
ajst-25630	83	20	actual	actual	ADJ
ajst-25630	83	21	kidney	kidney	NOUN
ajst-25630	83	22	injury	injury	NOUN
ajst-25630	83	23	by	by	ADP
ajst-25630	83	24	24	24	NUM
ajst-25630	83	25	-	-	SYM
ajst-25630	83	26	48	48	NUM
ajst-25630	83	27	hours	hour	NOUN
ajst-25630	83	28	.	.	PUNCT
ajst-25630	84	1	in	in	ADP
ajst-25630	84	2	contrast	contrast	NOUN
ajst-25630	84	3	,	,	PUNCT
ajst-25630	84	4	neutrophil	neutrophil	ADJ
ajst-25630	84	5	gelatinase	gelatinase	NOUN
ajst-25630	84	6	-	-	PUNCT
ajst-25630	84	7	associated	associate	VERB
ajst-25630	84	8	lipocalin	lipocalin	NOUN
ajst-25630	84	9	(	(	PUNCT
ajst-25630	84	10	ngal	ngal	ADJ
ajst-25630	84	11	)	)	PUNCT
ajst-25630	84	12	can	can	AUX
ajst-25630	84	13	be	be	AUX
ajst-25630	84	14	detected	detect	VERB
ajst-25630	84	15	to	to	PART
ajst-25630	84	16	rise	rise	VERB
ajst-25630	84	17	within	within	ADP
ajst-25630	84	18	2	2	NUM
ajst-25630	84	19	-	-	SYM
ajst-25630	84	20	6	6	NUM
ajst-25630	84	21	hours	hour	NOUN
ajst-25630	84	22	after	after	SCONJ
ajst-25630	84	23	aki	aki	NOUN
ajst-25630	84	24	occurs	occur	VERB
ajst-25630	84	25	[	[	X
ajst-25630	84	26	16	16	NUM
ajst-25630	84	27	]	]	PUNCT
ajst-25630	84	28	.	.	PUNCT
ajst-25630	85	1	this	this	DET
ajst-25630	85	2	early	early	ADJ
ajst-25630	85	3	diagnostic	diagnostic	ADJ
ajst-25630	85	4	capability	capability	NOUN
ajst-25630	85	5	provides	provide	VERB
ajst-25630	85	6	a	a	DET
ajst-25630	85	7	valuable	valuable	ADJ
ajst-25630	85	8	time	time	NOUN
ajst-25630	85	9	window	window	NOUN
ajst-25630	85	10	for	for	ADP
ajst-25630	85	11	timely	timely	ADJ
ajst-25630	85	12	intervention	intervention	NOUN
ajst-25630	85	13	.	.	PUNCT
ajst-25630	86	1	similarly	similarly	ADV
ajst-25630	86	2	,	,	PUNCT
ajst-25630	86	3	urinary	urinary	ADJ
ajst-25630	86	4	levels	level	NOUN
ajst-25630	86	5	of	of	ADP
ajst-25630	86	6	kidney	kidney	NOUN
ajst-25630	86	7	injury	injury	NOUN
ajst-25630	86	8	219	219	NUM
ajst-25630	86	9	molecule-1	molecule-1	PROPN
ajst-25630	86	10	(	(	PUNCT
ajst-25630	86	11	kim-1	kim-1	X
ajst-25630	86	12	)	)	PUNCT
ajst-25630	86	13	are	be	AUX
ajst-25630	86	14	closely	closely	ADV
ajst-25630	86	15	related	relate	VERB
ajst-25630	86	16	to	to	ADP
ajst-25630	86	17	the	the	DET
ajst-25630	86	18	severity	severity	NOUN
ajst-25630	86	19	and	and	CCONJ
ajst-25630	86	20	duration	duration	NOUN
ajst-25630	86	21	of	of	ADP
ajst-25630	86	22	aki	aki	NOUN
ajst-25630	86	23	and	and	CCONJ
ajst-25630	86	24	can	can	AUX
ajst-25630	86	25	be	be	AUX
ajst-25630	86	26	used	use	VERB
ajst-25630	86	27	to	to	PART
ajst-25630	86	28	predict	predict	VERB
ajst-25630	86	29	kidney	kidney	NOUN
ajst-25630	86	30	function	function	NOUN
ajst-25630	86	31	recovery[17	recovery[17	PROPN
ajst-25630	86	32	]	]	PUNCT
ajst-25630	86	33	.	.	PUNCT
ajst-25630	87	1	interleukin-18	interleukin-18	PROPN
ajst-25630	87	2	(	(	PUNCT
ajst-25630	87	3	il-18	il-18	PRON
ajst-25630	87	4	)	)	PUNCT
ajst-25630	87	5	shows	show	VERB
ajst-25630	87	6	significant	significant	ADJ
ajst-25630	87	7	elevation	elevation	NOUN
ajst-25630	87	8	in	in	ADP
ajst-25630	87	9	aki	aki	NOUN
ajst-25630	87	10	patients	patient	NOUN
ajst-25630	87	11	after	after	ADP
ajst-25630	87	12	cardiac	cardiac	ADJ
ajst-25630	87	13	surgery	surgery	NOUN
ajst-25630	87	14	,	,	PUNCT
ajst-25630	87	15	becoming	become	VERB
ajst-25630	87	16	a	a	DET
ajst-25630	87	17	potential	potential	ADJ
ajst-25630	87	18	early	early	ADJ
ajst-25630	87	19	warning	warning	NOUN
ajst-25630	87	20	indicator	indicator	NOUN
ajst-25630	88	1	[	[	X
ajst-25630	88	2	18](as	18](as	PROPN
ajst-25630	88	3	shown	show	VERB
ajst-25630	88	4	in	in	ADP
ajst-25630	88	5	figure	figure	NOUN
ajst-25630	88	6	1	1	NUM
ajst-25630	88	7	)	)	PUNCT
ajst-25630	88	8	.	.	PUNCT
ajst-25630	89	1	the	the	DET
ajst-25630	89	2	combined	combine	VERB
ajst-25630	89	3	use	use	NOUN
ajst-25630	89	4	of	of	ADP
ajst-25630	89	5	these	these	DET
ajst-25630	89	6	markers	marker	NOUN
ajst-25630	89	7	may	may	AUX
ajst-25630	89	8	further	far	ADV
ajst-25630	89	9	improve	improve	VERB
ajst-25630	89	10	the	the	DET
ajst-25630	89	11	accuracy	accuracy	NOUN
ajst-25630	89	12	and	and	CCONJ
ajst-25630	89	13	timeliness	timeliness	NOUN
ajst-25630	89	14	of	of	ADP
ajst-25630	89	15	aki	aki	NOUN
ajst-25630	89	16	diagnosis	diagnosis	NOUN
ajst-25630	89	17	.	.	PUNCT
ajst-25630	90	1	figure	figure	NOUN
ajst-25630	90	2	1	1	NUM
ajst-25630	90	3	.	.	PUNCT
ajst-25630	91	1	distribution	distribution	NOUN
ajst-25630	91	2	of	of	ADP
ajst-25630	91	3	urinary	urinary	ADJ
ajst-25630	91	4	il-18	il-18	ADP
ajst-25630	91	5	,	,	PUNCT
ajst-25630	91	6	urinary	urinary	ADJ
ajst-25630	91	7	ngal	ngal	ADJ
ajst-25630	91	8	,	,	PUNCT
ajst-25630	91	9	and	and	CCONJ
ajst-25630	91	10	plasma	plasma	NOUN
ajst-25630	91	11	ngal	ngal	ADV
ajst-25630	91	12	in	in	ADP
ajst-25630	91	13	aki	aki	NOUN
ajst-25630	91	14	patients	patient	NOUN
ajst-25630	91	15	after	after	ADP
ajst-25630	91	16	cardiac	cardiac	ADJ
ajst-25630	91	17	surgery	surgery	NOUN
ajst-25630	92	1	[	[	X
ajst-25630	92	2	15	15	NUM
ajst-25630	92	3	]	]	PUNCT
ajst-25630	92	4	in	in	ADP
ajst-25630	92	5	the	the	DET
ajst-25630	92	6	field	field	NOUN
ajst-25630	92	7	of	of	ADP
ajst-25630	92	8	chronic	chronic	ADJ
ajst-25630	92	9	kidney	kidney	NOUN
ajst-25630	92	10	disease	disease	NOUN
ajst-25630	92	11	(	(	PUNCT
ajst-25630	92	12	ckd	ckd	NOUN
ajst-25630	92	13	)	)	PUNCT
ajst-25630	92	14	,	,	PUNCT
ajst-25630	92	15	novel	novel	NOUN
ajst-25630	92	16	markers	marker	NOUN
ajst-25630	92	17	play	play	VERB
ajst-25630	92	18	important	important	ADJ
ajst-25630	92	19	roles	role	NOUN
ajst-25630	92	20	in	in	ADP
ajst-25630	92	21	early	early	ADJ
ajst-25630	92	22	diagnosis	diagnosis	NOUN
ajst-25630	92	23	and	and	CCONJ
ajst-25630	92	24	progression	progression	NOUN
ajst-25630	92	25	monitoring	monitoring	NOUN
ajst-25630	92	26	.	.	PUNCT
ajst-25630	93	1	the	the	DET
ajst-25630	93	2	combination	combination	NOUN
ajst-25630	93	3	of	of	ADP
ajst-25630	93	4	cystatin	cystatin	PROPN
ajst-25630	93	5	c	c	PROPN
ajst-25630	93	6	(	(	PUNCT
ajst-25630	93	7	cysc	cysc	NOUN
ajst-25630	93	8	)	)	PUNCT
ajst-25630	93	9	and	and	CCONJ
ajst-25630	93	10	estimated	estimate	VERB
ajst-25630	93	11	glomerular	glomerular	ADJ
ajst-25630	93	12	filtration	filtration	NOUN
ajst-25630	93	13	rate	rate	NOUN
ajst-25630	93	14	(	(	PUNCT
ajst-25630	93	15	egfr	egfr	X
ajst-25630	93	16	)	)	PUNCT
ajst-25630	93	17	significantly	significantly	ADV
ajst-25630	93	18	improves	improve	VERB
ajst-25630	93	19	the	the	DET
ajst-25630	93	20	accuracy	accuracy	NOUN
ajst-25630	93	21	of	of	ADP
ajst-25630	93	22	early	early	ADJ
ajst-25630	93	23	ckd	ckd	PROPN
ajst-25630	93	24	diagnosis	diagnosis	NOUN
ajst-25630	93	25	[	[	X
ajst-25630	93	26	19	19	NUM
ajst-25630	93	27	]	]	PUNCT
ajst-25630	93	28	.	.	PUNCT
ajst-25630	94	1	urinary	urinary	ADJ
ajst-25630	94	2	levels	level	NOUN
ajst-25630	94	3	of	of	ADP
ajst-25630	94	4	liver	liver	NOUN
ajst-25630	94	5	-	-	PUNCT
ajst-25630	94	6	type	type	NOUN
ajst-25630	94	7	fatty	fatty	NOUN
ajst-25630	94	8	acid	acid	NOUN
ajst-25630	94	9	-	-	PUNCT
ajst-25630	94	10	binding	bind	VERB
ajst-25630	94	11	protein	protein	NOUN
ajst-25630	94	12	(	(	PUNCT
ajst-25630	94	13	l	l	NOUN
ajst-25630	94	14	-	-	PUNCT
ajst-25630	94	15	fabp	fabp	NOUN
ajst-25630	94	16	)	)	PUNCT
ajst-25630	94	17	are	be	AUX
ajst-25630	94	18	closely	closely	ADV
ajst-25630	94	19	related	relate	VERB
ajst-25630	94	20	to	to	ADP
ajst-25630	94	21	ckd	ckd	PROPN
ajst-25630	94	22	progression	progression	NOUN
ajst-25630	94	23	rate	rate	NOUN
ajst-25630	94	24	,	,	PUNCT
ajst-25630	94	25	providing	provide	VERB
ajst-25630	94	26	a	a	DET
ajst-25630	94	27	new	new	ADJ
ajst-25630	94	28	tool	tool	NOUN
ajst-25630	94	29	for	for	ADP
ajst-25630	94	30	predicting	predict	VERB
ajst-25630	94	31	kidney	kidney	NOUN
ajst-25630	94	32	function	function	NOUN
ajst-25630	94	33	decline	decline	NOUN
ajst-25630	95	1	[	[	X
ajst-25630	95	2	20](as	20](as	NOUN
ajst-25630	95	3	shown	show	VERB
ajst-25630	95	4	in	in	ADP
ajst-25630	95	5	figure	figure	NOUN
ajst-25630	95	6	2	2	NUM
ajst-25630	95	7	)	)	PUNCT
ajst-25630	95	8	.	.	PUNCT
ajst-25630	96	1	moreover	moreover	ADV
ajst-25630	96	2	,	,	PUNCT
ajst-25630	96	3	serum	serum	PROPN
ajst-25630	96	4	ngal	ngal	ADJ
ajst-25630	96	5	levels	level	NOUN
ajst-25630	96	6	correlate	correlate	VERB
ajst-25630	96	7	with	with	ADP
ajst-25630	96	8	ckd	ckd	NOUN
ajst-25630	96	9	staging	staging	NOUN
ajst-25630	96	10	,	,	PUNCT
ajst-25630	96	11	reflecting	reflect	VERB
ajst-25630	96	12	disease	disease	NOUN
ajst-25630	96	13	severity	severity	NOUN
ajst-25630	96	14	[	[	X
ajst-25630	96	15	21	21	NUM
ajst-25630	96	16	]	]	PUNCT
ajst-25630	96	17	.	.	PUNCT
ajst-25630	97	1	the	the	DET
ajst-25630	97	2	application	application	NOUN
ajst-25630	97	3	of	of	ADP
ajst-25630	97	4	these	these	DET
ajst-25630	97	5	markers	marker	NOUN
ajst-25630	97	6	not	not	PART
ajst-25630	97	7	only	only	ADV
ajst-25630	97	8	aids	aid	NOUN
ajst-25630	97	9	in	in	ADP
ajst-25630	97	10	early	early	ADJ
ajst-25630	97	11	diagnosis	diagnosis	NOUN
ajst-25630	97	12	of	of	ADP
ajst-25630	97	13	ckd	ckd	PROPN
ajst-25630	97	14	but	but	CCONJ
ajst-25630	97	15	also	also	ADV
ajst-25630	97	16	provides	provide	VERB
ajst-25630	97	17	new	new	ADJ
ajst-25630	97	18	bases	basis	NOUN
ajst-25630	97	19	for	for	ADP
ajst-25630	97	20	individualized	individualized	ADJ
ajst-25630	97	21	treatment	treatment	NOUN
ajst-25630	97	22	and	and	CCONJ
ajst-25630	97	23	prognosis	prognosis	NOUN
ajst-25630	97	24	assessment	assessment	NOUN
ajst-25630	97	25	.	.	PUNCT
ajst-25630	98	1	figure	figure	NOUN
ajst-25630	98	2	2	2	NUM
ajst-25630	98	3	.	.	PUNCT
ajst-25630	99	1	comparison	comparison	NOUN
ajst-25630	99	2	of	of	ADP
ajst-25630	99	3	general	general	ADJ
ajst-25630	99	4	data	datum	NOUN
ajst-25630	99	5	among	among	ADP
ajst-25630	99	6	ckd	ckd	PROPN
ajst-25630	99	7	stages	stage	NOUN
ajst-25630	99	8	1	1	NUM
ajst-25630	99	9	-	-	SYM
ajst-25630	99	10	5	5	NUM
ajst-25630	99	11	[	[	SYM
ajst-25630	99	12	20	20	NUM
ajst-25630	99	13	]	]	PUNCT
ajst-25630	99	14	diabetic	diabetic	ADJ
ajst-25630	99	15	nephropathy	nephropathy	NOUN
ajst-25630	99	16	(	(	PUNCT
ajst-25630	99	17	dn	dn	NOUN
ajst-25630	99	18	)	)	PUNCT
ajst-25630	99	19	,	,	PUNCT
ajst-25630	99	20	as	as	ADP
ajst-25630	99	21	one	one	NUM
ajst-25630	99	22	of	of	ADP
ajst-25630	99	23	the	the	DET
ajst-25630	99	24	leading	lead	VERB
ajst-25630	99	25	causes	cause	NOUN
ajst-25630	99	26	of	of	ADP
ajst-25630	99	27	end	end	NOUN
ajst-25630	99	28	-	-	PUNCT
ajst-25630	99	29	stage	stage	NOUN
ajst-25630	99	30	renal	renal	ADJ
ajst-25630	99	31	disease	disease	NOUN
ajst-25630	99	32	,	,	PUNCT
ajst-25630	99	33	requires	require	VERB
ajst-25630	99	34	particular	particular	ADJ
ajst-25630	99	35	attention	attention	NOUN
ajst-25630	99	36	to	to	ADP
ajst-25630	99	37	early	early	ADJ
ajst-25630	99	38	diagnosis	diagnosis	NOUN
ajst-25630	99	39	and	and	CCONJ
ajst-25630	99	40	progression	progression	NOUN
ajst-25630	99	41	monitoring	monitoring	NOUN
ajst-25630	99	42	.	.	PUNCT
ajst-25630	100	1	traditionally	traditionally	ADV
ajst-25630	100	2	,	,	PUNCT
ajst-25630	100	3	microalbuminuria	microalbuminuria	PROPN
ajst-25630	100	4	was	be	AUX
ajst-25630	100	5	considered	consider	VERB
ajst-25630	100	6	an	an	DET
ajst-25630	100	7	early	early	ADJ
ajst-25630	100	8	marker	marker	NOUN
ajst-25630	100	9	of	of	ADP
ajst-25630	100	10	dn	dn	PROPN
ajst-25630	100	11	.	.	PUNCT
ajst-25630	101	1	however	however	ADV
ajst-25630	101	2	,	,	PUNCT
ajst-25630	101	3	studies	study	NOUN
ajst-25630	101	4	have	have	AUX
ajst-25630	101	5	found	find	VERB
ajst-25630	101	6	that	that	SCONJ
ajst-25630	101	7	kim-1	kim-1	ADJ
ajst-25630	101	8	may	may	AUX
ajst-25630	101	9	rise	rise	VERB
ajst-25630	101	10	in	in	ADP
ajst-25630	101	11	the	the	DET
ajst-25630	101	12	microalbuminuria	microalbuminuria	ADJ
ajst-25630	101	13	stage	stage	NOUN
ajst-25630	101	14	,	,	PUNCT
ajst-25630	101	15	potentially	potentially	ADV
ajst-25630	101	16	becoming	become	VERB
ajst-25630	101	17	an	an	DET
ajst-25630	101	18	earlier	early	ADJ
ajst-25630	101	19	marker	marker	NOUN
ajst-25630	101	20	for	for	ADP
ajst-25630	101	21	dn[22	dn[22	PROPN
ajst-25630	101	22	]	]	PUNCT
ajst-25630	101	23	.	.	PUNCT
ajst-25630	102	1	urinary	urinary	ADJ
ajst-25630	102	2	l	l	ADJ
ajst-25630	102	3	-	-	ADJ
ajst-25630	102	4	fabp	fabp	ADJ
ajst-25630	102	5	levels	level	NOUN
ajst-25630	102	6	are	be	AUX
ajst-25630	102	7	closely	closely	ADV
ajst-25630	102	8	related	relate	VERB
ajst-25630	102	9	to	to	ADP
ajst-25630	102	10	dn	dn	VERB
ajst-25630	102	11	progression	progression	NOUN
ajst-25630	102	12	and	and	CCONJ
ajst-25630	102	13	can	can	AUX
ajst-25630	102	14	be	be	AUX
ajst-25630	102	15	used	use	VERB
ajst-25630	102	16	to	to	PART
ajst-25630	102	17	predict	predict	VERB
ajst-25630	102	18	the	the	DET
ajst-25630	102	19	occurrence	occurrence	NOUN
ajst-25630	102	20	of	of	ADP
ajst-25630	102	21	massive	massive	ADJ
ajst-25630	102	22	proteinuria	proteinuria	NOUN
ajst-25630	103	1	[	[	X
ajst-25630	103	2	23	23	NUM
ajst-25630	103	3	]	]	PUNCT
ajst-25630	103	4	.	.	PUNCT
ajst-25630	104	1	these	these	DET
ajst-25630	104	2	findings	finding	NOUN
ajst-25630	104	3	open	open	VERB
ajst-25630	104	4	new	new	ADJ
ajst-25630	104	5	avenues	avenue	NOUN
ajst-25630	104	6	for	for	ADP
ajst-25630	104	7	early	early	ADJ
ajst-25630	104	8	intervention	intervention	NOUN
ajst-25630	104	9	and	and	CCONJ
ajst-25630	104	10	individualized	individualized	ADJ
ajst-25630	104	11	management	management	NOUN
ajst-25630	104	12	of	of	ADP
ajst-25630	104	13	dn	dn	PROPN
ajst-25630	104	14	.	.	PROPN
ajst-25630	105	1	in	in	ADP
ajst-25630	105	2	the	the	DET
ajst-25630	105	3	field	field	NOUN
ajst-25630	105	4	of	of	ADP
ajst-25630	105	5	kidney	kidney	NOUN
ajst-25630	105	6	transplantation	transplantation	NOUN
ajst-25630	105	7	,	,	PUNCT
ajst-25630	105	8	novel	novel	ADJ
ajst-25630	105	9	biomarkers	biomarker	NOUN
ajst-25630	105	10	show	show	VERB
ajst-25630	105	11	significant	significant	ADJ
ajst-25630	105	12	results	result	NOUN
ajst-25630	105	13	in	in	ADP
ajst-25630	105	14	assessing	assess	VERB
ajst-25630	105	15	transplant	transplant	NOUN
ajst-25630	105	16	kidney	kidney	NOUN
ajst-25630	105	17	function	function	NOUN
ajst-25630	105	18	and	and	CCONJ
ajst-25630	105	19	predicting	predict	VERB
ajst-25630	105	20	rejection	rejection	NOUN
ajst-25630	105	21	reactions	reaction	NOUN
ajst-25630	105	22	.	.	PUNCT
ajst-25630	106	1	urinary	urinary	ADJ
ajst-25630	106	2	ngal	ngal	NOUN
ajst-25630	106	3	has	have	AUX
ajst-25630	106	4	been	be	AUX
ajst-25630	106	5	found	find	VERB
ajst-25630	106	6	to	to	PART
ajst-25630	106	7	predict	predict	VERB
ajst-25630	106	8	delayed	delay	VERB
ajst-25630	106	9	graft	graft	NOUN
ajst-25630	106	10	function	function	NOUN
ajst-25630	106	11	early	early	ADV
ajst-25630	106	12	[	[	X
ajst-25630	106	13	24	24	NUM
ajst-25630	106	14	]	]	PUNCT
ajst-25630	106	15	,	,	PUNCT
ajst-25630	106	16	which	which	PRON
ajst-25630	106	17	is	be	AUX
ajst-25630	106	18	of	of	ADP
ajst-25630	106	19	great	great	ADJ
ajst-25630	106	20	significance	significance	NOUN
ajst-25630	106	21	for	for	ADP
ajst-25630	106	22	timely	timely	ADJ
ajst-25630	106	23	adjustment	adjustment	NOUN
ajst-25630	106	24	of	of	ADP
ajst-25630	106	25	immunosuppressive	immunosuppressive	ADJ
ajst-25630	106	26	regimens	regimen	NOUN
ajst-25630	106	27	.	.	PUNCT
ajst-25630	107	1	elevated	elevated	ADJ
ajst-25630	107	2	urinary	urinary	ADJ
ajst-25630	107	3	il-18	il-18	PRON
ajst-25630	107	4	levels	level	NOUN
ajst-25630	107	5	may	may	AUX
ajst-25630	107	6	indicate	indicate	VERB
ajst-25630	107	7	the	the	DET
ajst-25630	107	8	occurrence	occurrence	NOUN
ajst-25630	107	9	of	of	ADP
ajst-25630	107	10	acute	acute	ADJ
ajst-25630	107	11	rejection[25	rejection[25	NOUN
ajst-25630	107	12	]	]	X
ajst-25630	107	13	,	,	PUNCT
ajst-25630	107	14	providing	provide	VERB
ajst-25630	107	15	new	new	ADJ
ajst-25630	107	16	tools	tool	NOUN
ajst-25630	107	17	for	for	ADP
ajst-25630	107	18	early	early	ADJ
ajst-25630	107	19	diagnosis	diagnosis	NOUN
ajst-25630	107	20	and	and	CCONJ
ajst-25630	107	21	treatment	treatment	NOUN
ajst-25630	107	22	of	of	ADP
ajst-25630	107	23	rejection	rejection	NOUN
ajst-25630	107	24	reactions	reaction	NOUN
ajst-25630	107	25	.	.	PUNCT
ajst-25630	108	1	the	the	DET
ajst-25630	108	2	application	application	NOUN
ajst-25630	108	3	of	of	ADP
ajst-25630	108	4	these	these	DET
ajst-25630	108	5	markers	marker	NOUN
ajst-25630	108	6	is	be	AUX
ajst-25630	108	7	expected	expect	VERB
ajst-25630	108	8	to	to	PART
ajst-25630	108	9	improve	improve	VERB
ajst-25630	108	10	the	the	DET
ajst-25630	108	11	success	success	NOUN
ajst-25630	108	12	rate	rate	NOUN
ajst-25630	108	13	and	and	CCONJ
ajst-25630	108	14	long	long	ADJ
ajst-25630	108	15	-	-	PUNCT
ajst-25630	108	16	term	term	NOUN
ajst-25630	108	17	prognosis	prognosis	NOUN
ajst-25630	108	18	of	of	ADP
ajst-25630	108	19	kidney	kidney	NOUN
ajst-25630	108	20	transplantation	transplantation	NOUN
ajst-25630	108	21	.	.	PUNCT
ajst-25630	109	1	in	in	ADP
ajst-25630	109	2	monitoring	monitor	VERB
ajst-25630	109	3	drug	drug	NOUN
ajst-25630	109	4	-	-	PUNCT
ajst-25630	109	5	induced	induce	VERB
ajst-25630	109	6	kidney	kidney	NOUN
ajst-25630	109	7	injury	injury	NOUN
ajst-25630	109	8	,	,	PUNCT
ajst-25630	109	9	novel	novel	ADJ
ajst-25630	109	10	biomarkers	biomarker	NOUN
ajst-25630	109	11	also	also	ADV
ajst-25630	109	12	show	show	VERB
ajst-25630	109	13	unique	unique	ADJ
ajst-25630	109	14	advantages	advantage	NOUN
ajst-25630	109	15	.	.	PUNCT
ajst-25630	110	1	kim-1	kim-1	X
ajst-25630	110	2	has	have	AUX
ajst-25630	110	3	been	be	AUX
ajst-25630	110	4	recognized	recognize	VERB
ajst-25630	110	5	by	by	ADP
ajst-25630	110	6	the	the	DET
ajst-25630	110	7	u.s	u.s	PROPN
ajst-25630	110	8	.	.	PROPN
ajst-25630	110	9	food	food	PROPN
ajst-25630	110	10	and	and	CCONJ
ajst-25630	110	11	drug	drug	PROPN
ajst-25630	110	12	administration	administration	PROPN
ajst-25630	110	13	(	(	PUNCT
ajst-25630	110	14	fda	fda	PROPN
ajst-25630	110	15	)	)	PUNCT
ajst-25630	110	16	as	as	ADP
ajst-25630	110	17	a	a	DET
ajst-25630	110	18	biomarker	biomarker	NOUN
ajst-25630	110	19	of	of	ADP
ajst-25630	110	20	drug	drug	NOUN
ajst-25630	110	21	-	-	PUNCT
ajst-25630	110	22	induced	induce	VERB
ajst-25630	110	23	nephrotoxicity[26	nephrotoxicity[26	NOUN
ajst-25630	110	24	]	]	PUNCT
ajst-25630	110	25	,	,	PUNCT
ajst-25630	110	26	greatly	greatly	ADV
ajst-25630	110	27	promoting	promote	VERB
ajst-25630	110	28	its	its	PRON
ajst-25630	110	29	application	application	NOUN
ajst-25630	110	30	in	in	ADP
ajst-25630	110	31	drug	drug	NOUN
ajst-25630	110	32	development	development	NOUN
ajst-25630	110	33	and	and	CCONJ
ajst-25630	110	34	safety	safety	NOUN
ajst-25630	110	35	assessment	assessment	NOUN
ajst-25630	110	36	.	.	PUNCT
ajst-25630	111	1	ngal	ngal	PROPN
ajst-25630	111	2	has	have	AUX
ajst-25630	111	3	been	be	AUX
ajst-25630	111	4	proven	prove	VERB
ajst-25630	111	5	to	to	PART
ajst-25630	111	6	early	early	ADJ
ajst-25630	111	7	detect	detect	VERB
ajst-25630	111	8	kidney	kidney	NOUN
ajst-25630	111	9	injury	injury	NOUN
ajst-25630	111	10	caused	cause	VERB
ajst-25630	111	11	by	by	ADP
ajst-25630	111	12	certain	certain	ADJ
ajst-25630	111	13	antibiotics	antibiotic	NOUN
ajst-25630	111	14	and	and	CCONJ
ajst-25630	111	15	contrast	contrast	VERB
ajst-25630	111	16	agents	agent	NOUN
ajst-25630	112	1	[	[	X
ajst-25630	112	2	27	27	NUM
ajst-25630	112	3	]	]	PUNCT
ajst-25630	112	4	,	,	PUNCT
ajst-25630	112	5	providing	provide	VERB
ajst-25630	112	6	important	important	ADJ
ajst-25630	112	7	safeguards	safeguard	NOUN
ajst-25630	112	8	for	for	ADP
ajst-25630	112	9	clinical	clinical	ADJ
ajst-25630	112	10	medication	medication	NOUN
ajst-25630	112	11	safety	safety	NOUN
ajst-25630	112	12	.	.	PUNCT
ajst-25630	113	1	these	these	DET
ajst-25630	113	2	application	application	NOUN
ajst-25630	113	3	examples	example	NOUN
ajst-25630	113	4	fully	fully	ADV
ajst-25630	113	5	demonstrate	demonstrate	VERB
ajst-25630	113	6	the	the	DET
ajst-25630	113	7	enormous	enormous	ADJ
ajst-25630	113	8	potential	potential	NOUN
ajst-25630	113	9	of	of	ADP
ajst-25630	113	10	novel	novel	ADJ
ajst-25630	113	11	biomarkers	biomarker	NOUN
ajst-25630	113	12	in	in	ADP
ajst-25630	113	13	improving	improve	VERB
ajst-25630	113	14	the	the	DET
ajst-25630	113	15	accuracy	accuracy	NOUN
ajst-25630	113	16	of	of	ADP
ajst-25630	113	17	kidney	kidney	NOUN
ajst-25630	113	18	disease	disease	NOUN
ajst-25630	113	19	diagnosis	diagnosis	NOUN
ajst-25630	113	20	and	and	CCONJ
ajst-25630	113	21	improving	improve	VERB
ajst-25630	113	22	patient	patient	ADJ
ajst-25630	113	23	prognosis	prognosis	NOUN
ajst-25630	113	24	.	.	PUNCT
ajst-25630	114	1	they	they	PRON
ajst-25630	114	2	not	not	PART
ajst-25630	114	3	only	only	ADV
ajst-25630	114	4	easily	easily	ADV
ajst-25630	114	5	identify	identify	VERB
ajst-25630	114	6	kidney	kidney	NOUN
ajst-25630	114	7	injury	injury	NOUN
ajst-25630	114	8	but	but	CCONJ
ajst-25630	114	9	can	can	AUX
ajst-25630	114	10	also	also	ADV
ajst-25630	114	11	more	more	ADV
ajst-25630	114	12	accurately	accurately	ADV
ajst-25630	114	13	assess	assess	VERB
ajst-25630	114	14	disease	disease	NOUN
ajst-25630	114	15	severity	severity	NOUN
ajst-25630	114	16	and	and	CCONJ
ajst-25630	114	17	predict	predict	VERB
ajst-25630	114	18	prognosis	prognosis	NOUN
ajst-25630	114	19	.	.	PUNCT
ajst-25630	115	1	220	220	NUM
ajst-25630	115	2	5	5	NUM
ajst-25630	115	3	.	.	PUNCT
ajst-25630	116	1	multi	multi	ADJ
ajst-25630	116	2	-	-	NOUN
ajst-25630	116	3	marker	marker	NOUN
ajst-25630	116	4	combined	combine	VERB
ajst-25630	116	5	detection	detection	NOUN
ajst-25630	116	6	strategy	strategy	NOUN
ajst-25630	116	7	as	as	ADP
ajst-25630	116	8	the	the	DET
ajst-25630	116	9	understanding	understanding	NOUN
ajst-25630	116	10	of	of	ADP
ajst-25630	116	11	the	the	DET
ajst-25630	116	12	complexity	complexity	NOUN
ajst-25630	116	13	and	and	CCONJ
ajst-25630	116	14	heterogeneity	heterogeneity	NOUN
ajst-25630	116	15	of	of	ADP
ajst-25630	116	16	kidney	kidney	NOUN
ajst-25630	116	17	diseases	disease	NOUN
ajst-25630	116	18	deepens	deepen	VERB
ajst-25630	116	19	,	,	PUNCT
ajst-25630	116	20	a	a	DET
ajst-25630	116	21	single	single	ADJ
ajst-25630	116	22	biomarker	biomarker	NOUN
ajst-25630	116	23	may	may	AUX
ajst-25630	116	24	struggle	struggle	VERB
ajst-25630	116	25	to	to	PART
ajst-25630	116	26	comprehensively	comprehensively	ADV
ajst-25630	116	27	reflect	reflect	VERB
ajst-25630	116	28	disease	disease	NOUN
ajst-25630	116	29	status	status	NOUN
ajst-25630	116	30	,	,	PUNCT
ajst-25630	116	31	thus	thus	ADV
ajst-25630	116	32	promoting	promote	VERB
ajst-25630	116	33	the	the	DET
ajst-25630	116	34	development	development	NOUN
ajst-25630	116	35	of	of	ADP
ajst-25630	116	36	multi	multi	ADJ
ajst-25630	116	37	-	-	NOUN
ajst-25630	116	38	marker	marker	NOUN
ajst-25630	116	39	combined	combine	VERB
ajst-25630	116	40	detection	detection	NOUN
ajst-25630	116	41	strategies	strategy	NOUN
ajst-25630	116	42	.	.	PUNCT
ajst-25630	117	1	this	this	DET
ajst-25630	117	2	strategy	strategy	NOUN
ajst-25630	117	3	is	be	AUX
ajst-25630	117	4	gradually	gradually	ADV
ajst-25630	117	5	becoming	become	VERB
ajst-25630	117	6	a	a	DET
ajst-25630	117	7	new	new	ADJ
ajst-25630	117	8	trend	trend	NOUN
ajst-25630	117	9	in	in	ADP
ajst-25630	117	10	the	the	DET
ajst-25630	117	11	field	field	NOUN
ajst-25630	117	12	of	of	ADP
ajst-25630	117	13	kidney	kidney	NOUN
ajst-25630	117	14	disease	disease	NOUN
ajst-25630	117	15	diagnosis	diagnosis	NOUN
ajst-25630	117	16	and	and	CCONJ
ajst-25630	117	17	monitoring	monitoring	NOUN
ajst-25630	117	18	.	.	PUNCT
ajst-25630	118	1	the	the	DET
ajst-25630	118	2	theoretical	theoretical	ADJ
ajst-25630	118	3	basis	basis	NOUN
ajst-25630	118	4	of	of	ADP
ajst-25630	118	5	multi	multi	ADJ
ajst-25630	118	6	-	-	NOUN
ajst-25630	118	7	marker	marker	NOUN
ajst-25630	118	8	combined	combine	VERB
ajst-25630	118	9	detection	detection	NOUN
ajst-25630	118	10	strategy	strategy	NOUN
ajst-25630	118	11	stems	stem	VERB
ajst-25630	118	12	from	from	ADP
ajst-25630	118	13	the	the	DET
ajst-25630	118	14	characteristics	characteristic	NOUN
ajst-25630	118	15	of	of	ADP
ajst-25630	118	16	different	different	ADJ
ajst-25630	118	17	biomarkers	biomarker	NOUN
ajst-25630	118	18	reflecting	reflect	VERB
ajst-25630	118	19	different	different	ADJ
ajst-25630	118	20	aspects	aspect	NOUN
ajst-25630	118	21	of	of	ADP
ajst-25630	118	22	kidney	kidney	NOUN
ajst-25630	118	23	injury	injury	NOUN
ajst-25630	118	24	.	.	PUNCT
ajst-25630	119	1	for	for	ADP
ajst-25630	119	2	example	example	NOUN
ajst-25630	119	3	,	,	PUNCT
ajst-25630	119	4	cystatin	cystatin	PROPN
ajst-25630	119	5	c	c	PROPN
ajst-25630	119	6	mainly	mainly	ADV
ajst-25630	119	7	reflects	reflect	VERB
ajst-25630	119	8	glomerular	glomerular	ADJ
ajst-25630	119	9	function	function	NOUN
ajst-25630	119	10	,	,	PUNCT
ajst-25630	119	11	while	while	SCONJ
ajst-25630	119	12	kidney	kidney	NOUN
ajst-25630	119	13	injury	injury	NOUN
ajst-25630	119	14	molecule-1	molecule-1	PROPN
ajst-25630	119	15	(	(	PUNCT
ajst-25630	119	16	kim-1	kim-1	X
ajst-25630	119	17	)	)	PUNCT
ajst-25630	119	18	and	and	CCONJ
ajst-25630	119	19	neutrophil	neutrophil	NOUN
ajst-25630	119	20	gelatinaseassociated	gelatinaseassociate	VERB
ajst-25630	119	21	lipocalin	lipocalin	NOUN
ajst-25630	119	22	(	(	PUNCT
ajst-25630	119	23	ngal	ngal	ADJ
ajst-25630	119	24	)	)	PUNCT
ajst-25630	119	25	more	more	ADV
ajst-25630	119	26	reflect	reflect	VERB
ajst-25630	119	27	tubular	tubular	ADJ
ajst-25630	119	28	injury	injury	NOUN
ajst-25630	119	29	;	;	PUNCT
ajst-25630	119	30	interleukin-18	interleukin-18	PROPN
ajst-25630	119	31	(	(	PUNCT
ajst-25630	119	32	il-18	il-18	NUM
ajst-25630	119	33	)	)	PUNCT
ajst-25630	119	34	,	,	PUNCT
ajst-25630	119	35	as	as	ADP
ajst-25630	119	36	an	an	DET
ajst-25630	119	37	inflammatory	inflammatory	ADJ
ajst-25630	119	38	factor	factor	NOUN
ajst-25630	119	39	,	,	PUNCT
ajst-25630	119	40	can	can	AUX
ajst-25630	119	41	provide	provide	VERB
ajst-25630	119	42	information	information	NOUN
ajst-25630	119	43	about	about	ADP
ajst-25630	119	44	the	the	DET
ajst-25630	119	45	kidney	kidney	NOUN
ajst-25630	119	46	's	's	PART
ajst-25630	119	47	inflammatory	inflammatory	ADJ
ajst-25630	119	48	state	state	NOUN
ajst-25630	119	49	.	.	PUNCT
ajst-25630	120	1	in	in	ADP
ajst-25630	120	2	the	the	DET
ajst-25630	120	3	diagnosis	diagnosis	NOUN
ajst-25630	120	4	of	of	ADP
ajst-25630	120	5	acute	acute	ADJ
ajst-25630	120	6	kidney	kidney	NOUN
ajst-25630	120	7	injury	injury	NOUN
ajst-25630	120	8	(	(	PUNCT
ajst-25630	120	9	aki	aki	NOUN
ajst-25630	120	10	)	)	PUNCT
ajst-25630	120	11	,	,	PUNCT
ajst-25630	120	12	a	a	DET
ajst-25630	120	13	study	study	NOUN
ajst-25630	120	14	on	on	ADP
ajst-25630	120	15	patients	patient	NOUN
ajst-25630	120	16	after	after	ADP
ajst-25630	120	17	cardiac	cardiac	ADJ
ajst-25630	120	18	surgery	surgery	NOUN
ajst-25630	120	19	showed	show	VERB
ajst-25630	120	20	that	that	SCONJ
ajst-25630	120	21	the	the	DET
ajst-25630	120	22	combined	combined	ADJ
ajst-25630	120	23	detection	detection	NOUN
ajst-25630	120	24	of	of	ADP
ajst-25630	120	25	ngal	ngal	ADJ
ajst-25630	120	26	,	,	PUNCT
ajst-25630	120	27	il-18	il-18	ADP
ajst-25630	120	28	,	,	PUNCT
ajst-25630	120	29	and	and	CCONJ
ajst-25630	120	30	kim-1	kim-1	X
ajst-25630	120	31	more	more	ADV
ajst-25630	120	32	accurately	accurately	ADV
ajst-25630	120	33	predicted	predict	VERB
ajst-25630	120	34	the	the	DET
ajst-25630	120	35	occurrence	occurrence	NOUN
ajst-25630	120	36	of	of	ADP
ajst-25630	120	37	aki	aki	NOUN
ajst-25630	120	38	than	than	ADP
ajst-25630	120	39	any	any	DET
ajst-25630	120	40	single	single	ADJ
ajst-25630	120	41	marker	marker	NOUN
ajst-25630	120	42	[	[	X
ajst-25630	120	43	28	28	NUM
ajst-25630	120	44	]	]	PUNCT
ajst-25630	120	45	.	.	PUNCT
ajst-25630	121	1	in	in	ADP
ajst-25630	121	2	predicting	predict	VERB
ajst-25630	121	3	the	the	DET
ajst-25630	121	4	progression	progression	NOUN
ajst-25630	121	5	of	of	ADP
ajst-25630	121	6	chronic	chronic	ADJ
ajst-25630	121	7	kidney	kidney	NOUN
ajst-25630	121	8	disease	disease	NOUN
ajst-25630	121	9	(	(	PUNCT
ajst-25630	121	10	ckd	ckd	PROPN
ajst-25630	121	11	)	)	PUNCT
ajst-25630	121	12	,	,	PUNCT
ajst-25630	121	13	the	the	DET
ajst-25630	121	14	combined	combined	ADJ
ajst-25630	121	15	use	use	NOUN
ajst-25630	121	16	of	of	ADP
ajst-25630	121	17	cystatin	cystatin	PROPN
ajst-25630	121	18	c	c	PROPN
ajst-25630	121	19	,	,	PUNCT
ajst-25630	121	20	ngal	ngal	ADJ
ajst-25630	121	21	,	,	PUNCT
ajst-25630	121	22	and	and	CCONJ
ajst-25630	121	23	liver	liver	NOUN
ajst-25630	121	24	-	-	PUNCT
ajst-25630	121	25	type	type	NOUN
ajst-25630	121	26	fatty	fatty	NOUN
ajst-25630	121	27	acid	acid	NOUN
ajst-25630	121	28	-	-	PUNCT
ajst-25630	121	29	binding	bind	VERB
ajst-25630	121	30	protein	protein	NOUN
ajst-25630	121	31	(	(	PUNCT
ajst-25630	121	32	l	l	NOUN
ajst-25630	121	33	-	-	PUNCT
ajst-25630	121	34	fabp	fabp	NOUN
ajst-25630	121	35	)	)	PUNCT
ajst-25630	121	36	may	may	AUX
ajst-25630	121	37	better	well	ADV
ajst-25630	121	38	predict	predict	VERB
ajst-25630	121	39	ckd	ckd	PROPN
ajst-25630	121	40	progression	progression	NOUN
ajst-25630	121	41	than	than	ADP
ajst-25630	121	42	using	use	VERB
ajst-25630	121	43	estimated	estimate	VERB
ajst-25630	121	44	glomerular	glomerular	ADJ
ajst-25630	121	45	filtration	filtration	NOUN
ajst-25630	121	46	rate	rate	NOUN
ajst-25630	121	47	(	(	PUNCT
ajst-25630	121	48	egfr	egfr	X
ajst-25630	121	49	)	)	PUNCT
ajst-25630	121	50	alone	alone	ADV
ajst-25630	122	1	[	[	X
ajst-25630	122	2	29	29	NUM
ajst-25630	122	3	]	]	PUNCT
ajst-25630	122	4	.	.	PUNCT
ajst-25630	123	1	in	in	ADP
ajst-25630	123	2	the	the	DET
ajst-25630	123	3	early	early	ADJ
ajst-25630	123	4	diagnosis	diagnosis	NOUN
ajst-25630	123	5	of	of	ADP
ajst-25630	123	6	diabetic	diabetic	ADJ
ajst-25630	123	7	nephropathy	nephropathy	NOUN
ajst-25630	123	8	(	(	PUNCT
ajst-25630	123	9	dn	dn	NOUN
ajst-25630	123	10	)	)	PUNCT
ajst-25630	123	11	,	,	PUNCT
ajst-25630	123	12	the	the	DET
ajst-25630	123	13	combined	combined	ADJ
ajst-25630	123	14	detection	detection	NOUN
ajst-25630	123	15	of	of	ADP
ajst-25630	123	16	kim-1	kim-1	SYM
ajst-25630	123	17	,	,	PUNCT
ajst-25630	123	18	ngal	ngal	ADJ
ajst-25630	123	19	,	,	PUNCT
ajst-25630	123	20	and	and	CCONJ
ajst-25630	123	21	l	l	NOUN
ajst-25630	123	22	-	-	NOUN
ajst-25630	123	23	fabp	fabp	NOUN
ajst-25630	123	24	shows	show	VERB
ajst-25630	123	25	potential	potential	NOUN
ajst-25630	123	26	to	to	PART
ajst-25630	123	27	improve	improve	VERB
ajst-25630	123	28	diagnostic	diagnostic	ADJ
ajst-25630	123	29	sensitivity	sensitivity	NOUN
ajst-25630	123	30	and	and	CCONJ
ajst-25630	123	31	specificity	specificity	NOUN
ajst-25630	123	32	[	[	X
ajst-25630	123	33	30	30	NUM
ajst-25630	123	34	]	]	PUNCT
ajst-25630	123	35	(	(	PUNCT
ajst-25630	123	36	as	as	SCONJ
ajst-25630	123	37	shown	show	VERB
ajst-25630	123	38	in	in	ADP
ajst-25630	123	39	figures	figure	NOUN
ajst-25630	123	40	3	3	NUM
ajst-25630	123	41	and	and	CCONJ
ajst-25630	123	42	4	4	NUM
ajst-25630	123	43	)	)	PUNCT
ajst-25630	123	44	.	.	PUNCT
ajst-25630	124	1	by	by	ADP
ajst-25630	124	2	combining	combine	VERB
ajst-25630	124	3	these	these	DET
ajst-25630	124	4	markers	marker	NOUN
ajst-25630	124	5	reflecting	reflect	VERB
ajst-25630	124	6	different	different	ADJ
ajst-25630	124	7	physiological	physiological	ADJ
ajst-25630	124	8	and	and	CCONJ
ajst-25630	124	9	pathological	pathological	ADJ
ajst-25630	124	10	processes	process	NOUN
ajst-25630	124	11	,	,	PUNCT
ajst-25630	124	12	we	we	PRON
ajst-25630	124	13	hope	hope	VERB
ajst-25630	124	14	to	to	PART
ajst-25630	124	15	obtain	obtain	VERB
ajst-25630	124	16	a	a	DET
ajst-25630	124	17	more	more	ADV
ajst-25630	124	18	comprehensive	comprehensive	ADJ
ajst-25630	124	19	and	and	CCONJ
ajst-25630	124	20	accurate	accurate	ADJ
ajst-25630	124	21	assessment	assessment	NOUN
ajst-25630	124	22	of	of	ADP
ajst-25630	124	23	kidney	kidney	NOUN
ajst-25630	124	24	health	health	NOUN
ajst-25630	124	25	status	status	NOUN
ajst-25630	124	26	.	.	PUNCT
ajst-25630	125	1	figure	figure	VERB
ajst-25630	125	2	3	3	NUM
ajst-25630	125	3	.	.	PUNCT
ajst-25630	125	4	positive	positive	ADJ
ajst-25630	125	5	detection	detection	NOUN
ajst-25630	125	6	rates	rate	NOUN
ajst-25630	125	7	based	base	VERB
ajst-25630	125	8	on	on	ADP
ajst-25630	125	9	single	single	ADJ
ajst-25630	125	10	and	and	CCONJ
ajst-25630	125	11	multiple	multiple	ADJ
ajst-25630	125	12	indicators	indicator	NOUN
ajst-25630	125	13	in	in	ADP
ajst-25630	125	14	the	the	DET
ajst-25630	125	15	dn	dn	PROPN
ajst-25630	125	16	group[31	group[31	PROPN
ajst-25630	125	17	]	]	X
ajst-25630	125	18	figure	figure	NOUN
ajst-25630	125	19	4	4	NUM
ajst-25630	125	20	.	.	PUNCT
ajst-25630	126	1	diagnostic	diagnostic	ADJ
ajst-25630	126	2	value	value	NOUN
ajst-25630	126	3	of	of	ADP
ajst-25630	126	4	serum	serum	NOUN
ajst-25630	126	5	d	d	PROPN
ajst-25630	126	6	-	-	PUNCT
ajst-25630	126	7	d	d	PROPN
ajst-25630	126	8	,	,	PUNCT
ajst-25630	126	9	kim-1	kim-1	NOUN
ajst-25630	126	10	,	,	PUNCT
ajst-25630	126	11	and	and	CCONJ
ajst-25630	126	12	urinary	urinary	ADJ
ajst-25630	126	13	rbp	rbp	PROPN
ajst-25630	126	14	levels	level	NOUN
ajst-25630	126	15	for	for	ADP
ajst-25630	126	16	early	early	ADJ
ajst-25630	126	17	dn	dn	NOUN
ajst-25630	127	1	[	[	X
ajst-25630	127	2	32	32	NUM
ajst-25630	127	3	]	]	PUNCT
ajst-25630	127	4	however	however	ADV
ajst-25630	127	5	,	,	PUNCT
ajst-25630	127	6	the	the	DET
ajst-25630	127	7	widespread	widespread	ADJ
ajst-25630	127	8	application	application	NOUN
ajst-25630	127	9	of	of	ADP
ajst-25630	127	10	multi	multi	ADJ
ajst-25630	127	11	-	-	NOUN
ajst-25630	127	12	marker	marker	NOUN
ajst-25630	127	13	strategies	strategy	NOUN
ajst-25630	127	14	in	in	ADP
ajst-25630	127	15	clinical	clinical	ADJ
ajst-25630	127	16	practice	practice	NOUN
ajst-25630	127	17	still	still	ADV
ajst-25630	127	18	faces	face	VERB
ajst-25630	127	19	some	some	DET
ajst-25630	127	20	challenges	challenge	NOUN
ajst-25630	127	21	.	.	PUNCT
ajst-25630	128	1	first	first	ADV
ajst-25630	128	2	is	be	AUX
ajst-25630	128	3	the	the	DET
ajst-25630	128	4	standardization	standardization	NOUN
ajst-25630	128	5	issue	issue	NOUN
ajst-25630	128	6	:	:	PUNCT
ajst-25630	128	7	different	different	ADJ
ajst-25630	128	8	laboratories	laboratory	NOUN
ajst-25630	128	9	and	and	CCONJ
ajst-25630	128	10	detection	detection	NOUN
ajst-25630	128	11	methods	method	NOUN
ajst-25630	128	12	may	may	AUX
ajst-25630	128	13	lead	lead	VERB
ajst-25630	128	14	to	to	ADP
ajst-25630	128	15	differences	difference	NOUN
ajst-25630	128	16	in	in	ADP
ajst-25630	128	17	results	result	NOUN
ajst-25630	128	18	,	,	PUNCT
ajst-25630	128	19	and	and	CCONJ
ajst-25630	128	20	establishing	establish	VERB
ajst-25630	128	21	unified	unified	ADJ
ajst-25630	128	22	detection	detection	NOUN
ajst-25630	128	23	standards	standard	NOUN
ajst-25630	128	24	and	and	CCONJ
ajst-25630	128	25	reference	reference	NOUN
ajst-25630	128	26	ranges	range	VERB
ajst-25630	128	27	is	be	AUX
ajst-25630	128	28	an	an	DET
ajst-25630	128	29	important	important	ADJ
ajst-25630	128	30	direction	direction	NOUN
ajst-25630	128	31	for	for	ADP
ajst-25630	128	32	future	future	ADJ
ajst-25630	128	33	research	research	NOUN
ajst-25630	128	34	.	.	PUNCT
ajst-25630	129	1	second	second	ADJ
ajst-25630	129	2	is	be	AUX
ajst-25630	129	3	the	the	DET
ajst-25630	129	4	cost	cost	NOUN
ajst-25630	129	5	-	-	PUNCT
ajst-25630	129	6	effectiveness	effectiveness	NOUN
ajst-25630	129	7	issue	issue	NOUN
ajst-25630	129	8	:	:	PUNCT
ajst-25630	129	9	multiple	multiple	ADJ
ajst-25630	129	10	tests	test	NOUN
ajst-25630	129	11	will	will	AUX
ajst-25630	129	12	undoubtedly	undoubtedly	ADV
ajst-25630	129	13	increase	increase	VERB
ajst-25630	129	14	medical	medical	ADJ
ajst-25630	129	15	costs	cost	NOUN
ajst-25630	129	16	.	.	PUNCT
ajst-25630	130	1	how	how	SCONJ
ajst-25630	130	2	to	to	PART
ajst-25630	130	3	find	find	VERB
ajst-25630	130	4	a	a	DET
ajst-25630	130	5	balance	balance	NOUN
ajst-25630	130	6	between	between	ADP
ajst-25630	130	7	improving	improve	VERB
ajst-25630	130	8	diagnostic	diagnostic	ADJ
ajst-25630	130	9	accuracy	accuracy	NOUN
ajst-25630	130	10	and	and	CCONJ
ajst-25630	130	11	controlling	control	VERB
ajst-25630	130	12	medical	medical	ADJ
ajst-25630	130	13	costs	cost	NOUN
ajst-25630	130	14	requires	require	VERB
ajst-25630	130	15	in	in	ADP
ajst-25630	130	16	-	-	PUNCT
ajst-25630	130	17	depth	depth	NOUN
ajst-25630	130	18	health	health	NOUN
ajst-25630	130	19	economics	economic	NOUN
ajst-25630	130	20	assessments	assessment	NOUN
ajst-25630	130	21	.	.	PUNCT
ajst-25630	131	1	in	in	ADP
ajst-25630	131	2	the	the	DET
ajst-25630	131	3	future	future	NOUN
ajst-25630	131	4	,	,	PUNCT
ajst-25630	131	5	research	research	NOUN
ajst-25630	131	6	on	on	ADP
ajst-25630	131	7	multi	multi	ADJ
ajst-25630	131	8	-	-	NOUN
ajst-25630	131	9	marker	marker	NOUN
ajst-25630	131	10	combined	combine	VERB
ajst-25630	131	11	detection	detection	NOUN
ajst-25630	131	12	strategies	strategy	NOUN
ajst-25630	131	13	may	may	AUX
ajst-25630	131	14	develop	develop	VERB
ajst-25630	131	15	in	in	ADP
ajst-25630	131	16	several	several	ADJ
ajst-25630	131	17	directions	direction	NOUN
ajst-25630	131	18	.	.	PUNCT
ajst-25630	132	1	first	first	ADV
ajst-25630	132	2	is	be	AUX
ajst-25630	132	3	exploring	explore	VERB
ajst-25630	132	4	individualized	individualized	ADJ
ajst-25630	132	5	marker	marker	NOUN
ajst-25630	132	6	combinations	combination	NOUN
ajst-25630	132	7	to	to	PART
ajst-25630	132	8	adapt	adapt	VERB
ajst-25630	132	9	to	to	ADP
ajst-25630	132	10	different	different	ADJ
ajst-25630	132	11	types	type	NOUN
ajst-25630	132	12	of	of	ADP
ajst-25630	132	13	kidney	kidney	NOUN
ajst-25630	132	14	diseases	disease	NOUN
ajst-25630	132	15	and	and	CCONJ
ajst-25630	132	16	patient	patient	ADJ
ajst-25630	132	17	characteristics	characteristic	NOUN
ajst-25630	132	18	.	.	PUNCT
ajst-25630	133	1	second	second	ADJ
ajst-25630	133	2	is	be	AUX
ajst-25630	133	3	studying	study	VERB
ajst-25630	133	4	the	the	DET
ajst-25630	133	5	clinical	clinical	ADJ
ajst-25630	133	6	significance	significance	NOUN
ajst-25630	133	7	of	of	ADP
ajst-25630	133	8	dynamic	dynamic	ADJ
ajst-25630	133	9	changes	change	NOUN
ajst-25630	133	10	in	in	ADP
ajst-25630	133	11	markers	marker	NOUN
ajst-25630	133	12	,	,	PUNCT
ajst-25630	133	13	rather	rather	ADV
ajst-25630	133	14	than	than	ADP
ajst-25630	133	15	just	just	ADV
ajst-25630	133	16	focusing	focus	VERB
ajst-25630	133	17	on	on	ADP
ajst-25630	133	18	levels	level	NOUN
ajst-25630	133	19	at	at	ADP
ajst-25630	133	20	a	a	DET
ajst-25630	133	21	single	single	ADJ
ajst-25630	133	22	time	time	NOUN
ajst-25630	133	23	point	point	NOUN
ajst-25630	133	24	.	.	PUNCT
ajst-25630	134	1	finally	finally	ADV
ajst-25630	134	2	,	,	PUNCT
ajst-25630	134	3	combining	combine	VERB
ajst-25630	134	4	these	these	DET
ajst-25630	134	5	novel	novel	ADJ
ajst-25630	134	6	markers	marker	NOUN
ajst-25630	134	7	with	with	ADP
ajst-25630	134	8	traditional	traditional	ADJ
ajst-25630	134	9	clinical	clinical	ADJ
ajst-25630	134	10	parameters	parameter	NOUN
ajst-25630	134	11	and	and	CCONJ
ajst-25630	134	12	imaging	imaging	NOUN
ajst-25630	134	13	examination	examination	NOUN
ajst-25630	134	14	results	result	NOUN
ajst-25630	134	15	may	may	AUX
ajst-25630	134	16	221	221	NUM
ajst-25630	134	17	provide	provide	VERB
ajst-25630	134	18	a	a	DET
ajst-25630	134	19	new	new	ADJ
ajst-25630	134	20	paradigm	paradigm	NOUN
ajst-25630	134	21	for	for	ADP
ajst-25630	134	22	comprehensive	comprehensive	ADJ
ajst-25630	134	23	assessment	assessment	NOUN
ajst-25630	134	24	of	of	ADP
ajst-25630	134	25	kidney	kidney	NOUN
ajst-25630	134	26	diseases	disease	NOUN
ajst-25630	134	27	.	.	PUNCT
ajst-25630	135	1	in	in	ADP
ajst-25630	135	2	summary	summary	NOUN
ajst-25630	135	3	,	,	PUNCT
ajst-25630	135	4	multi	multi	ADJ
ajst-25630	135	5	-	-	NOUN
ajst-25630	135	6	marker	marker	NOUN
ajst-25630	135	7	combined	combine	VERB
ajst-25630	135	8	detection	detection	NOUN
ajst-25630	135	9	strategies	strategy	NOUN
ajst-25630	135	10	represent	represent	VERB
ajst-25630	135	11	the	the	DET
ajst-25630	135	12	future	future	ADJ
ajst-25630	135	13	development	development	NOUN
ajst-25630	135	14	direction	direction	NOUN
ajst-25630	135	15	of	of	ADP
ajst-25630	135	16	kidney	kidney	NOUN
ajst-25630	135	17	disease	disease	NOUN
ajst-25630	135	18	diagnosis	diagnosis	NOUN
ajst-25630	135	19	and	and	CCONJ
ajst-25630	135	20	monitoring	monitoring	NOUN
ajst-25630	135	21	.	.	PUNCT
ajst-25630	136	1	they	they	PRON
ajst-25630	136	2	are	be	AUX
ajst-25630	136	3	expected	expect	VERB
ajst-25630	136	4	to	to	PART
ajst-25630	136	5	significantly	significantly	ADV
ajst-25630	136	6	improve	improve	VERB
ajst-25630	136	7	the	the	DET
ajst-25630	136	8	accuracy	accuracy	NOUN
ajst-25630	136	9	and	and	CCONJ
ajst-25630	136	10	timeliness	timeliness	NOUN
ajst-25630	136	11	of	of	ADP
ajst-25630	136	12	clinical	clinical	ADJ
ajst-25630	136	13	decisionmaking	decisionmaking	NOUN
ajst-25630	136	14	.	.	PUNCT
ajst-25630	137	1	however	however	ADV
ajst-25630	137	2	,	,	PUNCT
ajst-25630	137	3	to	to	PART
ajst-25630	137	4	truly	truly	ADV
ajst-25630	137	5	translate	translate	VERB
ajst-25630	137	6	this	this	DET
ajst-25630	137	7	strategy	strategy	NOUN
ajst-25630	137	8	into	into	ADP
ajst-25630	137	9	clinical	clinical	ADJ
ajst-25630	137	10	practice	practice	NOUN
ajst-25630	137	11	,	,	PUNCT
ajst-25630	137	12	more	more	ADV
ajst-25630	137	13	large	large	ADJ
ajst-25630	137	14	-	-	PUNCT
ajst-25630	137	15	scale	scale	NOUN
ajst-25630	137	16	,	,	PUNCT
ajst-25630	137	17	multi	multi	ADJ
ajst-25630	137	18	-	-	ADJ
ajst-25630	137	19	center	center	ADJ
ajst-25630	137	20	prospective	prospective	ADJ
ajst-25630	137	21	studies	study	NOUN
ajst-25630	137	22	are	be	AUX
ajst-25630	137	23	needed	need	VERB
ajst-25630	137	24	to	to	PART
ajst-25630	137	25	verify	verify	VERB
ajst-25630	137	26	its	its	PRON
ajst-25630	137	27	effectiveness	effectiveness	NOUN
ajst-25630	137	28	and	and	CCONJ
ajst-25630	137	29	solve	solve	VERB
ajst-25630	137	30	practical	practical	ADJ
ajst-25630	137	31	problems	problem	NOUN
ajst-25630	137	32	such	such	ADJ
ajst-25630	137	33	as	as	ADP
ajst-25630	137	34	standardization	standardization	NOUN
ajst-25630	137	35	and	and	CCONJ
ajst-25630	137	36	cost	cost	NOUN
ajst-25630	137	37	-	-	PUNCT
ajst-25630	137	38	effectiveness	effectiveness	NOUN
ajst-25630	137	39	.	.	PUNCT
ajst-25630	138	1	with	with	ADP
ajst-25630	138	2	deepening	deepen	VERB
ajst-25630	138	3	research	research	NOUN
ajst-25630	138	4	and	and	CCONJ
ajst-25630	138	5	technological	technological	ADJ
ajst-25630	138	6	progress	progress	NOUN
ajst-25630	138	7	,	,	PUNCT
ajst-25630	138	8	we	we	PRON
ajst-25630	138	9	have	have	VERB
ajst-25630	138	10	reason	reason	NOUN
ajst-25630	138	11	to	to	PART
ajst-25630	138	12	expect	expect	VERB
ajst-25630	138	13	multi	multi	ADJ
ajst-25630	138	14	-	-	NOUN
ajst-25630	138	15	marker	marker	NOUN
ajst-25630	138	16	strategies	strategy	NOUN
ajst-25630	138	17	to	to	PART
ajst-25630	138	18	bring	bring	VERB
ajst-25630	138	19	substantial	substantial	ADJ
ajst-25630	138	20	clinical	clinical	ADJ
ajst-25630	138	21	benefits	benefit	NOUN
ajst-25630	138	22	to	to	ADP
ajst-25630	138	23	kidney	kidney	NOUN
ajst-25630	138	24	disease	disease	NOUN
ajst-25630	138	25	patients	patient	NOUN
ajst-25630	138	26	in	in	ADP
ajst-25630	138	27	the	the	DET
ajst-25630	138	28	near	near	ADJ
ajst-25630	138	29	future	future	NOUN
ajst-25630	138	30	.	.	PUNCT
ajst-25630	139	1	6	6	X
ajst-25630	139	2	.	.	X
ajst-25630	139	3	summary	summary	NOUN
ajst-25630	139	4	and	and	CCONJ
ajst-25630	139	5	outlook	outlook	VERB
ajst-25630	139	6	this	this	DET
ajst-25630	139	7	review	review	NOUN
ajst-25630	139	8	comprehensively	comprehensively	ADV
ajst-25630	139	9	explores	explore	VERB
ajst-25630	139	10	the	the	DET
ajst-25630	139	11	application	application	NOUN
ajst-25630	139	12	prospects	prospect	NOUN
ajst-25630	139	13	of	of	ADP
ajst-25630	139	14	novel	novel	ADJ
ajst-25630	139	15	kidney	kidney	NOUN
ajst-25630	139	16	disease	disease	NOUN
ajst-25630	139	17	biomarkers	biomarker	NOUN
ajst-25630	139	18	in	in	ADP
ajst-25630	139	19	early	early	ADJ
ajst-25630	139	20	diagnosis	diagnosis	NOUN
ajst-25630	139	21	and	and	CCONJ
ajst-25630	139	22	disease	disease	NOUN
ajst-25630	139	23	monitoring	monitoring	NOUN
ajst-25630	139	24	,	,	PUNCT
ajst-25630	139	25	while	while	SCONJ
ajst-25630	139	26	also	also	ADV
ajst-25630	139	27	deeply	deeply	ADV
ajst-25630	139	28	analyzing	analyze	VERB
ajst-25630	139	29	the	the	DET
ajst-25630	139	30	potential	potential	NOUN
ajst-25630	139	31	of	of	ADP
ajst-25630	139	32	multi	multi	ADJ
ajst-25630	139	33	-	-	NOUN
ajst-25630	139	34	marker	marker	NOUN
ajst-25630	139	35	combined	combine	VERB
ajst-25630	139	36	detection	detection	NOUN
ajst-25630	139	37	strategies	strategy	NOUN
ajst-25630	139	38	.	.	PUNCT
ajst-25630	140	1	with	with	ADP
ajst-25630	140	2	the	the	DET
ajst-25630	140	3	rapid	rapid	ADJ
ajst-25630	140	4	development	development	NOUN
ajst-25630	140	5	of	of	ADP
ajst-25630	140	6	molecular	molecular	ADJ
ajst-25630	140	7	biology	biology	NOUN
ajst-25630	140	8	and	and	CCONJ
ajst-25630	140	9	proteomics	proteomic	NOUN
ajst-25630	140	10	,	,	PUNCT
ajst-25630	140	11	we	we	PRON
ajst-25630	140	12	are	be	AUX
ajst-25630	140	13	standing	stand	VERB
ajst-25630	140	14	at	at	ADP
ajst-25630	140	15	the	the	DET
ajst-25630	140	16	threshold	threshold	NOUN
ajst-25630	140	17	of	of	ADP
ajst-25630	140	18	a	a	DET
ajst-25630	140	19	new	new	ADJ
ajst-25630	140	20	era	era	NOUN
ajst-25630	140	21	in	in	ADP
ajst-25630	140	22	kidney	kidney	NOUN
ajst-25630	140	23	disease	disease	NOUN
ajst-25630	140	24	diagnosis	diagnosis	NOUN
ajst-25630	140	25	and	and	CCONJ
ajst-25630	140	26	management	management	NOUN
ajst-25630	140	27	.	.	PUNCT
ajst-25630	141	1	novel	novel	ADJ
ajst-25630	141	2	biomarkers	biomarker	NOUN
ajst-25630	141	3	show	show	VERB
ajst-25630	141	4	significant	significant	ADJ
ajst-25630	141	5	advantages	advantage	NOUN
ajst-25630	141	6	in	in	ADP
ajst-25630	141	7	sensitivity	sensitivity	NOUN
ajst-25630	141	8	and	and	CCONJ
ajst-25630	141	9	specificity	specificity	NOUN
ajst-25630	141	10	compared	compare	VERB
ajst-25630	141	11	to	to	ADP
ajst-25630	141	12	traditional	traditional	ADJ
ajst-25630	141	13	markers	marker	NOUN
ajst-25630	141	14	.	.	PUNCT
ajst-25630	142	1	they	they	PRON
ajst-25630	142	2	can	can	AUX
ajst-25630	142	3	not	not	PART
ajst-25630	142	4	only	only	ADV
ajst-25630	142	5	detect	detect	VERB
ajst-25630	142	6	kidney	kidney	NOUN
ajst-25630	142	7	injury	injury	NOUN
ajst-25630	142	8	earlier	early	ADV
ajst-25630	142	9	but	but	CCONJ
ajst-25630	142	10	also	also	ADV
ajst-25630	142	11	more	more	ADV
ajst-25630	142	12	accurately	accurately	ADV
ajst-25630	142	13	reflect	reflect	VERB
ajst-25630	142	14	the	the	DET
ajst-25630	142	15	type	type	NOUN
ajst-25630	142	16	and	and	CCONJ
ajst-25630	142	17	degree	degree	NOUN
ajst-25630	142	18	of	of	ADP
ajst-25630	142	19	injury	injury	NOUN
ajst-25630	142	20	.	.	PUNCT
ajst-25630	143	1	these	these	DET
ajst-25630	143	2	characteristics	characteristic	NOUN
ajst-25630	143	3	make	make	VERB
ajst-25630	143	4	novel	novel	ADJ
ajst-25630	143	5	markers	marker	NOUN
ajst-25630	143	6	show	show	VERB
ajst-25630	143	7	great	great	ADJ
ajst-25630	143	8	potential	potential	NOUN
ajst-25630	143	9	in	in	ADP
ajst-25630	143	10	multiple	multiple	ADJ
ajst-25630	143	11	areas	area	NOUN
ajst-25630	143	12	such	such	ADJ
ajst-25630	143	13	as	as	ADP
ajst-25630	143	14	early	early	ADJ
ajst-25630	143	15	diagnosis	diagnosis	NOUN
ajst-25630	143	16	of	of	ADP
ajst-25630	143	17	acute	acute	ADJ
ajst-25630	143	18	kidney	kidney	NOUN
ajst-25630	143	19	injury	injury	NOUN
ajst-25630	143	20	(	(	PUNCT
ajst-25630	143	21	aki	aki	NOUN
ajst-25630	143	22	)	)	PUNCT
ajst-25630	143	23	,	,	PUNCT
ajst-25630	143	24	progression	progression	NOUN
ajst-25630	143	25	monitoring	monitoring	NOUN
ajst-25630	143	26	of	of	ADP
ajst-25630	143	27	chronic	chronic	ADJ
ajst-25630	143	28	kidney	kidney	NOUN
ajst-25630	143	29	disease	disease	NOUN
ajst-25630	143	30	(	(	PUNCT
ajst-25630	143	31	ckd	ckd	NOUN
ajst-25630	143	32	)	)	PUNCT
ajst-25630	143	33	,	,	PUNCT
ajst-25630	143	34	and	and	CCONJ
ajst-25630	143	35	early	early	ADJ
ajst-25630	143	36	warning	warning	NOUN
ajst-25630	143	37	of	of	ADP
ajst-25630	143	38	diabetic	diabetic	ADJ
ajst-25630	143	39	nephropathy	nephropathy	NOUN
ajst-25630	143	40	(	(	PUNCT
ajst-25630	143	41	dn	dn	NOUN
ajst-25630	143	42	)	)	PUNCT
ajst-25630	143	43	.	.	PUNCT
ajst-25630	144	1	the	the	DET
ajst-25630	144	2	rise	rise	NOUN
ajst-25630	144	3	of	of	ADP
ajst-25630	144	4	multi	multi	ADJ
ajst-25630	144	5	-	-	NOUN
ajst-25630	144	6	marker	marker	NOUN
ajst-25630	144	7	combined	combine	VERB
ajst-25630	144	8	detection	detection	NOUN
ajst-25630	144	9	strategies	strategy	NOUN
ajst-25630	144	10	provides	provide	VERB
ajst-25630	144	11	new	new	ADJ
ajst-25630	144	12	ideas	idea	NOUN
ajst-25630	144	13	for	for	ADP
ajst-25630	144	14	solving	solve	VERB
ajst-25630	144	15	the	the	DET
ajst-25630	144	16	limitations	limitation	NOUN
ajst-25630	144	17	of	of	ADP
ajst-25630	144	18	single	single	ADJ
ajst-25630	144	19	markers	marker	NOUN
ajst-25630	144	20	.	.	PUNCT
ajst-25630	145	1	by	by	ADP
ajst-25630	145	2	combining	combine	VERB
ajst-25630	145	3	markers	marker	NOUN
ajst-25630	145	4	reflecting	reflect	VERB
ajst-25630	145	5	different	different	ADJ
ajst-25630	145	6	physiological	physiological	ADJ
ajst-25630	145	7	and	and	CCONJ
ajst-25630	145	8	pathological	pathological	ADJ
ajst-25630	145	9	processes	process	NOUN
ajst-25630	145	10	,	,	PUNCT
ajst-25630	145	11	we	we	PRON
ajst-25630	145	12	hope	hope	VERB
ajst-25630	145	13	to	to	PART
ajst-25630	145	14	obtain	obtain	VERB
ajst-25630	145	15	a	a	DET
ajst-25630	145	16	more	more	ADV
ajst-25630	145	17	comprehensive	comprehensive	ADJ
ajst-25630	145	18	and	and	CCONJ
ajst-25630	145	19	accurate	accurate	ADJ
ajst-25630	145	20	assessment	assessment	NOUN
ajst-25630	145	21	of	of	ADP
ajst-25630	145	22	kidney	kidney	NOUN
ajst-25630	145	23	health	health	NOUN
ajst-25630	145	24	status	status	NOUN
ajst-25630	145	25	.	.	PUNCT
ajst-25630	146	1	looking	look	VERB
ajst-25630	146	2	to	to	ADP
ajst-25630	146	3	the	the	DET
ajst-25630	146	4	future	future	NOUN
ajst-25630	146	5	,	,	PUNCT
ajst-25630	146	6	research	research	NOUN
ajst-25630	146	7	on	on	ADP
ajst-25630	146	8	novel	novel	ADJ
ajst-25630	146	9	kidney	kidney	NOUN
ajst-25630	146	10	disease	disease	NOUN
ajst-25630	146	11	biomarkers	biomarker	NOUN
ajst-25630	146	12	may	may	AUX
ajst-25630	146	13	develop	develop	VERB
ajst-25630	146	14	in	in	ADP
ajst-25630	146	15	several	several	ADJ
ajst-25630	146	16	directions	direction	NOUN
ajst-25630	146	17	:	:	PUNCT
ajst-25630	146	18	1	1	X
ajst-25630	146	19	.	.	X
ajst-25630	146	20	individualized	individualized	ADJ
ajst-25630	146	21	marker	marker	NOUN
ajst-25630	146	22	combinations	combination	NOUN
ajst-25630	146	23	:	:	PUNCT
ajst-25630	146	24	due	due	ADP
ajst-25630	146	25	to	to	ADP
ajst-25630	146	26	the	the	DET
ajst-25630	146	27	heterogeneity	heterogeneity	NOUN
ajst-25630	146	28	of	of	ADP
ajst-25630	146	29	kidney	kidney	NOUN
ajst-25630	146	30	diseases	disease	NOUN
ajst-25630	146	31	,	,	PUNCT
ajst-25630	146	32	future	future	ADJ
ajst-25630	146	33	research	research	NOUN
ajst-25630	146	34	may	may	AUX
ajst-25630	146	35	explore	explore	VERB
ajst-25630	146	36	individualized	individualized	ADJ
ajst-25630	146	37	marker	marker	NOUN
ajst-25630	146	38	combinations	combination	NOUN
ajst-25630	146	39	for	for	ADP
ajst-25630	146	40	different	different	ADJ
ajst-25630	146	41	types	type	NOUN
ajst-25630	146	42	of	of	ADP
ajst-25630	146	43	kidney	kidney	NOUN
ajst-25630	146	44	diseases	disease	NOUN
ajst-25630	146	45	and	and	CCONJ
ajst-25630	146	46	patient	patient	ADJ
ajst-25630	146	47	characteristics	characteristic	NOUN
ajst-25630	146	48	.	.	PUNCT
ajst-25630	147	1	2	2	X
ajst-25630	147	2	.	.	X
ajst-25630	147	3	dynamic	dynamic	ADJ
ajst-25630	147	4	monitoring	monitoring	NOUN
ajst-25630	147	5	:	:	PUNCT
ajst-25630	147	6	studying	study	VERB
ajst-25630	147	7	the	the	DET
ajst-25630	147	8	dynamic	dynamic	ADJ
ajst-25630	147	9	changes	change	NOUN
ajst-25630	147	10	of	of	ADP
ajst-25630	147	11	marker	marker	NOUN
ajst-25630	147	12	levels	level	NOUN
ajst-25630	147	13	may	may	AUX
ajst-25630	147	14	provide	provide	VERB
ajst-25630	147	15	more	more	ADV
ajst-25630	147	16	valuable	valuable	ADJ
ajst-25630	147	17	information	information	NOUN
ajst-25630	147	18	than	than	ADP
ajst-25630	147	19	measurements	measurement	NOUN
ajst-25630	147	20	at	at	ADP
ajst-25630	147	21	a	a	DET
ajst-25630	147	22	single	single	ADJ
ajst-25630	147	23	time	time	NOUN
ajst-25630	147	24	point	point	NOUN
ajst-25630	147	25	.	.	PUNCT
ajst-25630	148	1	this	this	DET
ajst-25630	148	2	method	method	NOUN
ajst-25630	148	3	may	may	AUX
ajst-25630	148	4	better	well	ADV
ajst-25630	148	5	reflect	reflect	VERB
ajst-25630	148	6	disease	disease	NOUN
ajst-25630	148	7	progression	progression	NOUN
ajst-25630	148	8	and	and	CCONJ
ajst-25630	148	9	treatment	treatment	NOUN
ajst-25630	148	10	effects	effect	NOUN
ajst-25630	148	11	.	.	PUNCT
ajst-25630	149	1	3	3	X
ajst-25630	149	2	.	.	X
ajst-25630	149	3	integration	integration	NOUN
ajst-25630	149	4	of	of	ADP
ajst-25630	149	5	multi	multi	ADJ
ajst-25630	149	6	-	-	ADJ
ajst-25630	149	7	dimensional	dimensional	ADJ
ajst-25630	149	8	information	information	NOUN
ajst-25630	149	9	:	:	PUNCT
ajst-25630	149	10	combining	combine	VERB
ajst-25630	149	11	novel	novel	ADJ
ajst-25630	149	12	biomarkers	biomarker	NOUN
ajst-25630	149	13	with	with	ADP
ajst-25630	149	14	traditional	traditional	ADJ
ajst-25630	149	15	clinical	clinical	ADJ
ajst-25630	149	16	parameters	parameter	NOUN
ajst-25630	149	17	,	,	PUNCT
ajst-25630	149	18	imaging	imaging	NOUN
ajst-25630	149	19	examination	examination	NOUN
ajst-25630	149	20	results	result	NOUN
ajst-25630	149	21	,	,	PUNCT
ajst-25630	149	22	and	and	CCONJ
ajst-25630	149	23	genomic	genomic	NOUN
ajst-25630	149	24	data	datum	NOUN
ajst-25630	149	25	may	may	AUX
ajst-25630	149	26	provide	provide	VERB
ajst-25630	149	27	a	a	DET
ajst-25630	149	28	new	new	ADJ
ajst-25630	149	29	paradigm	paradigm	NOUN
ajst-25630	149	30	for	for	ADP
ajst-25630	149	31	comprehensive	comprehensive	ADJ
ajst-25630	149	32	assessment	assessment	NOUN
ajst-25630	149	33	of	of	ADP
ajst-25630	149	34	kidney	kidney	NOUN
ajst-25630	149	35	diseases	disease	NOUN
ajst-25630	149	36	.	.	PUNCT
ajst-25630	150	1	4	4	X
ajst-25630	150	2	.	.	X
ajst-25630	150	3	application	application	NOUN
ajst-25630	150	4	of	of	ADP
ajst-25630	150	5	new	new	ADJ
ajst-25630	150	6	technologies	technology	NOUN
ajst-25630	150	7	:	:	PUNCT
ajst-25630	150	8	the	the	DET
ajst-25630	150	9	application	application	NOUN
ajst-25630	150	10	of	of	ADP
ajst-25630	150	11	emerging	emerge	VERB
ajst-25630	150	12	technologies	technology	NOUN
ajst-25630	150	13	such	such	ADJ
ajst-25630	150	14	as	as	ADP
ajst-25630	150	15	nanotechnology	nanotechnology	NOUN
ajst-25630	150	16	and	and	CCONJ
ajst-25630	150	17	microfluidic	microfluidic	ADJ
ajst-25630	150	18	chips	chip	NOUN
ajst-25630	150	19	may	may	AUX
ajst-25630	150	20	greatly	greatly	ADV
ajst-25630	150	21	reduce	reduce	VERB
ajst-25630	150	22	the	the	DET
ajst-25630	150	23	cost	cost	NOUN
ajst-25630	150	24	of	of	ADP
ajst-25630	150	25	marker	marker	NOUN
ajst-25630	150	26	detection	detection	NOUN
ajst-25630	150	27	and	and	CCONJ
ajst-25630	150	28	improve	improve	VERB
ajst-25630	150	29	the	the	DET
ajst-25630	150	30	accuracy	accuracy	NOUN
ajst-25630	150	31	and	and	CCONJ
ajst-25630	150	32	convenience	convenience	NOUN
ajst-25630	150	33	of	of	ADP
ajst-25630	150	34	detection	detection	NOUN
ajst-25630	150	35	.	.	PUNCT
ajst-25630	151	1	5	5	X
ajst-25630	151	2	.	.	X
ajst-25630	151	3	big	big	ADJ
ajst-25630	151	4	data	datum	NOUN
ajst-25630	151	5	and	and	CCONJ
ajst-25630	151	6	artificial	artificial	ADJ
ajst-25630	151	7	intelligence	intelligence	NOUN
ajst-25630	151	8	:	:	PUNCT
ajst-25630	151	9	using	use	VERB
ajst-25630	151	10	big	big	ADJ
ajst-25630	151	11	data	datum	NOUN
ajst-25630	151	12	analysis	analysis	NOUN
ajst-25630	151	13	and	and	CCONJ
ajst-25630	151	14	artificial	artificial	ADJ
ajst-25630	151	15	intelligence	intelligence	NOUN
ajst-25630	151	16	technology	technology	NOUN
ajst-25630	151	17	may	may	AUX
ajst-25630	151	18	discover	discover	VERB
ajst-25630	151	19	new	new	ADJ
ajst-25630	151	20	marker	marker	NOUN
ajst-25630	151	21	combinations	combination	NOUN
ajst-25630	151	22	or	or	CCONJ
ajst-25630	151	23	prediction	prediction	NOUN
ajst-25630	151	24	models	model	NOUN
ajst-25630	151	25	,	,	PUNCT
ajst-25630	151	26	further	far	ADV
ajst-25630	151	27	improving	improve	VERB
ajst-25630	151	28	the	the	DET
ajst-25630	151	29	accuracy	accuracy	NOUN
ajst-25630	151	30	of	of	ADP
ajst-25630	151	31	diagnosis	diagnosis	NOUN
ajst-25630	151	32	and	and	CCONJ
ajst-25630	151	33	prognosis	prognosis	NOUN
ajst-25630	151	34	assessment	assessment	NOUN
ajst-25630	151	35	.	.	PUNCT
ajst-25630	152	1	overall	overall	ADJ
ajst-25630	152	2	,	,	PUNCT
ajst-25630	152	3	research	research	NOUN
ajst-25630	152	4	on	on	ADP
ajst-25630	152	5	novel	novel	ADJ
ajst-25630	152	6	kidney	kidney	NOUN
ajst-25630	152	7	disease	disease	NOUN
ajst-25630	152	8	biomarkers	biomarker	NOUN
ajst-25630	152	9	is	be	AUX
ajst-25630	152	10	opening	open	VERB
ajst-25630	152	11	up	up	ADP
ajst-25630	152	12	new	new	ADJ
ajst-25630	152	13	prospects	prospect	NOUN
ajst-25630	152	14	for	for	ADP
ajst-25630	152	15	the	the	DET
ajst-25630	152	16	diagnosis	diagnosis	NOUN
ajst-25630	152	17	,	,	PUNCT
ajst-25630	152	18	monitoring	monitoring	NOUN
ajst-25630	152	19	,	,	PUNCT
ajst-25630	152	20	and	and	CCONJ
ajst-25630	152	21	management	management	NOUN
ajst-25630	152	22	of	of	ADP
ajst-25630	152	23	kidney	kidney	NOUN
ajst-25630	152	24	diseases	disease	NOUN
ajst-25630	152	25	.	.	PUNCT
ajst-25630	153	1	although	although	SCONJ
ajst-25630	153	2	many	many	ADJ
ajst-25630	153	3	challenges	challenge	NOUN
ajst-25630	153	4	remain	remain	VERB
ajst-25630	153	5	,	,	PUNCT
ajst-25630	153	6	with	with	ADP
ajst-25630	153	7	deepening	deepen	VERB
ajst-25630	153	8	research	research	NOUN
ajst-25630	153	9	and	and	CCONJ
ajst-25630	153	10	technological	technological	ADJ
ajst-25630	153	11	progress	progress	NOUN
ajst-25630	153	12	,	,	PUNCT
ajst-25630	153	13	we	we	PRON
ajst-25630	153	14	have	have	VERB
ajst-25630	153	15	reason	reason	NOUN
ajst-25630	153	16	to	to	PART
ajst-25630	153	17	expect	expect	VERB
ajst-25630	153	18	these	these	DET
ajst-25630	153	19	new	new	ADJ
ajst-25630	153	20	tools	tool	NOUN
ajst-25630	153	21	to	to	PART
ajst-25630	153	22	bring	bring	VERB
ajst-25630	153	23	revolutionary	revolutionary	ADJ
ajst-25630	153	24	changes	change	NOUN
ajst-25630	153	25	to	to	ADP
ajst-25630	153	26	clinical	clinical	ADJ
ajst-25630	153	27	practice	practice	NOUN
ajst-25630	153	28	in	in	ADP
ajst-25630	153	29	the	the	DET
ajst-25630	153	30	near	near	ADJ
ajst-25630	153	31	future	future	NOUN
ajst-25630	153	32	.	.	PUNCT
ajst-25630	154	1	references	reference	NOUN
ajst-25630	154	2	[	[	X
ajst-25630	154	3	1	1	NUM
ajst-25630	154	4	]	]	X
ajst-25630	154	5	zhao	zhao	PROPN
ajst-25630	154	6	,	,	PUNCT
ajst-25630	154	7	p.t	p.t	PROPN
ajst-25630	154	8	.	.	PROPN
ajst-25630	154	9	(	(	PUNCT
ajst-25630	154	10	2024	2024	NUM
ajst-25630	154	11	)	)	PUNCT
ajst-25630	154	12	.	.	PUNCT
ajst-25630	155	1	protective	protective	ADJ
ajst-25630	155	2	effect	effect	NOUN
ajst-25630	155	3	of	of	ADP
ajst-25630	155	4	cannabidiol	cannabidiol	NOUN
ajst-25630	155	5	on	on	ADP
ajst-25630	155	6	renal	renal	ADJ
ajst-25630	155	7	ischemia	ischemia	NOUN
ajst-25630	155	8	-	-	PUNCT
ajst-25630	155	9	reperfusion	reperfusion	NOUN
ajst-25630	155	10	injury	injury	NOUN
ajst-25630	155	11	in	in	ADP
ajst-25630	155	12	mice	mouse	NOUN
ajst-25630	156	1	[	[	X
ajst-25630	156	2	d	d	X
ajst-25630	156	3	]	]	X
ajst-25630	156	4	.	.	PUNCT
ajst-25630	157	1	hebei	hebei	PROPN
ajst-25630	157	2	north	north	PROPN
ajst-25630	157	3	university	university	PROPN
ajst-25630	157	4	.	.	PUNCT
ajst-25630	158	1	doi	doi	NOUN
ajst-25630	158	2	:	:	PUNCT
ajst-25630	158	3	10.27767	10.27767	NUM
ajst-25630	158	4	/	/	SYM
ajst-25630	158	5	d.cnki.ghbbf.2023.000375	d.cnki.ghbbf.2023.000375	NOUN
ajst-25630	158	6	.	.	PUNCT
ajst-25630	159	1	[	[	X
ajst-25630	159	2	2	2	NUM
ajst-25630	159	3	]	]	X
ajst-25630	159	4	lv	lv	PROPN
ajst-25630	159	5	,	,	PUNCT
ajst-25630	159	6	j.	j.	PROPN
ajst-25630	159	7	,	,	PUNCT
ajst-25630	159	8	&	&	CCONJ
ajst-25630	159	9	li	li	PROPN
ajst-25630	159	10	,	,	PUNCT
ajst-25630	159	11	m.m	m.m	PROPN
ajst-25630	159	12	.	.	PROPN
ajst-25630	159	13	(	(	PUNCT
ajst-25630	159	14	2020	2020	NUM
ajst-25630	159	15	)	)	PUNCT
ajst-25630	159	16	.	.	PUNCT
ajst-25630	160	1	research	research	NOUN
ajst-25630	160	2	progress	progress	NOUN
ajst-25630	160	3	of	of	ADP
ajst-25630	160	4	urinary	urinary	ADJ
ajst-25630	160	5	exosome	exosome	PROPN
ajst-25630	160	6	micrornas	microrna	NOUN
ajst-25630	160	7	in	in	ADP
ajst-25630	160	8	kidney	kidney	NOUN
ajst-25630	160	9	diseases	disease	NOUN
ajst-25630	161	1	[	[	X
ajst-25630	161	2	j	j	X
ajst-25630	161	3	]	]	X
ajst-25630	161	4	.	.	PUNCT
ajst-25630	162	1	chinese	chinese	ADJ
ajst-25630	162	2	journal	journal	PROPN
ajst-25630	162	3	of	of	ADP
ajst-25630	162	4	pathophysiology	pathophysiology	NOUN
ajst-25630	162	5	,	,	PUNCT
ajst-25630	162	6	36(02):378	36(02):378	NUM
ajst-25630	162	7	-	-	SYM
ajst-25630	162	8	384	384	NUM
ajst-25630	162	9	.	.	PUNCT
ajst-25630	163	1	[	[	X
ajst-25630	163	2	3	3	NUM
ajst-25630	163	3	]	]	X
ajst-25630	163	4	wang	wang	PROPN
ajst-25630	163	5	,	,	PUNCT
ajst-25630	163	6	q.s	q.s	PROPN
ajst-25630	163	7	.	.	PROPN
ajst-25630	163	8	(	(	PUNCT
ajst-25630	163	9	2017	2017	NUM
ajst-25630	163	10	)	)	PUNCT
ajst-25630	163	11	.	.	PUNCT
ajst-25630	163	12	study	study	NOUN
ajst-25630	163	13	on	on	ADP
ajst-25630	163	14	the	the	DET
ajst-25630	163	15	diagnostic	diagnostic	ADJ
ajst-25630	163	16	value	value	NOUN
ajst-25630	163	17	of	of	ADP
ajst-25630	163	18	urine	urine	NOUN
ajst-25630	163	19	microalbumin	microalbumin	NOUN
ajst-25630	163	20	/	/	SYM
ajst-25630	163	21	creatinine	creatinine	NOUN
ajst-25630	163	22	ratio	ratio	NOUN
ajst-25630	163	23	,	,	PUNCT
ajst-25630	163	24	serum	serum	NOUN
ajst-25630	163	25	creatinine	creatinine	NOUN
ajst-25630	163	26	and	and	CCONJ
ajst-25630	163	27	serum	serum	VERB
ajst-25630	163	28	cystatin	cystatin	PROPN
ajst-25630	163	29	c	c	PROPN
ajst-25630	163	30	for	for	ADP
ajst-25630	163	31	early	early	ADJ
ajst-25630	163	32	renal	renal	ADJ
ajst-25630	163	33	damage	damage	NOUN
ajst-25630	163	34	in	in	ADP
ajst-25630	163	35	elderly	elderly	ADJ
ajst-25630	163	36	hypertensive	hypertensive	ADJ
ajst-25630	163	37	patients	patient	NOUN
ajst-25630	163	38	[	[	X
ajst-25630	163	39	d	d	X
ajst-25630	163	40	]	]	X
ajst-25630	163	41	.	.	PUNCT
ajst-25630	164	1	soochow	soochow	PROPN
ajst-25630	164	2	university	university	NOUN
ajst-25630	164	3	.	.	PUNCT
ajst-25630	165	1	[	[	X
ajst-25630	165	2	4	4	NUM
ajst-25630	165	3	]	]	SYM
ajst-25630	165	4	li	li	PROPN
ajst-25630	165	5	,	,	PUNCT
ajst-25630	165	6	t.	t.	PROPN
ajst-25630	165	7	,	,	PUNCT
ajst-25630	165	8	wu	wu	PROPN
ajst-25630	165	9	,	,	PUNCT
ajst-25630	165	10	y.	y.	PROPN
ajst-25630	165	11	,	,	PUNCT
ajst-25630	165	12	yuan	yuan	PROPN
ajst-25630	165	13	,	,	PUNCT
ajst-25630	165	14	s.t	s.t	PROPN
ajst-25630	165	15	.	.	PROPN
ajst-25630	165	16	,	,	PUNCT
ajst-25630	165	17	et	et	PROPN
ajst-25630	165	18	al	al	PROPN
ajst-25630	165	19	.	.	PUNCT
ajst-25630	166	1	(	(	PUNCT
ajst-25630	166	2	2024	2024	NUM
ajst-25630	166	3	)	)	PUNCT
ajst-25630	166	4	.	.	PUNCT
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ajst-25630	167	2	progress	progress	NOUN
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ajst-25630	168	4	.	.	PUNCT
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ajst-25630	169	5	-	-	SYM
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ajst-25630	169	7	.	.	PUNCT
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ajst-25630	170	3	]	]	X
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ajst-25630	170	7	.	.	PROPN
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ajst-25630	170	10	)	)	PUNCT
ajst-25630	170	11	.	.	PUNCT
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ajst-25630	170	16	c	c	PROPN
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ajst-25630	171	1	[	[	X
ajst-25630	171	2	j	j	X
ajst-25630	171	3	]	]	X
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ajst-25630	172	8	-	-	SYM
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ajst-25630	172	10	.	.	PUNCT
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ajst-25630	173	3	]	]	X
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ajst-25630	174	7	-	-	PUNCT
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ajst-25630	174	12	:	:	PUNCT
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ajst-25630	175	1	[	[	X
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ajst-25630	175	4	.	.	PUNCT
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ajst-25630	176	4	)	)	PUNCT
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ajst-25630	177	8	,	,	PUNCT
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ajst-25630	177	11	n.	n.	NOUN
ajst-25630	177	12	,	,	PUNCT
ajst-25630	177	13	tran	tran	NOUN
ajst-25630	177	14	,	,	PUNCT
ajst-25630	177	15	t.	t.	PROPN
ajst-25630	177	16	,	,	PUNCT
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ajst-25630	177	20	(	(	PUNCT
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ajst-25630	177	23	.	.	PUNCT
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ajst-25630	178	6	:	:	PUNCT
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ajst-25630	179	4	.	.	PUNCT
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ajst-25630	180	11	)	)	PUNCT
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ajst-25630	181	3	]	]	SYM
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ajst-25630	181	11	.	.	PUNCT
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ajst-25630	182	5	ngal	ngal	NOUN
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ajst-25630	182	7	kim1	kim1	PROPN
ajst-25630	182	8	in	in	ADP
ajst-25630	182	9	acute	acute	ADJ
ajst-25630	182	10	kidney	kidney	NOUN
ajst-25630	182	11	injury	injury	NOUN
ajst-25630	182	12	before	before	ADP
ajst-25630	182	13	and	and	CCONJ
ajst-25630	182	14	after	after	ADP
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ajst-25630	182	16	-	-	PUNCT
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ajst-25630	182	18	methotrexate	methotrexate	NOUN
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ajst-25630	182	20	in	in	ADP
ajst-25630	182	21	children	child	NOUN
ajst-25630	182	22	with	with	ADP
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ajst-25630	182	24	lymphoblastic	lymphoblastic	ADJ
ajst-25630	182	25	leukemia	leukemia	NOUN
ajst-25630	183	1	[	[	X
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ajst-25630	183	3	]	]	X
ajst-25630	183	4	.	.	PUNCT
ajst-25630	184	1	zhengzhou	zhengzhou	PROPN
ajst-25630	184	2	university	university	PROPN
ajst-25630	184	3	.	.	PUNCT
ajst-25630	185	1	[	[	X
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ajst-25630	185	3	]	]	X
ajst-25630	185	4	wang	wang	PROPN
ajst-25630	185	5	,	,	PUNCT
ajst-25630	185	6	h.j	h.j	PROPN
ajst-25630	185	7	.	.	PROPN
ajst-25630	185	8	,	,	PUNCT
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ajst-25630	185	10	,	,	PUNCT
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ajst-25630	185	12	,	,	PUNCT
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ajst-25630	185	14	,	,	PUNCT
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ajst-25630	185	16	.	.	PROPN
ajst-25630	185	17	,	,	PUNCT
ajst-25630	185	18	et	et	PROPN
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ajst-25630	185	21	(	(	PUNCT
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ajst-25630	185	23	)	)	PUNCT
ajst-25630	185	24	.	.	PUNCT
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ajst-25630	186	4	detection	detection	NOUN
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ajst-25630	186	6	multiple	multiple	ADJ
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ajst-25630	186	8	markers	marker	NOUN
ajst-25630	186	9	for	for	ADP
ajst-25630	186	10	early	early	ADJ
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ajst-25630	186	12	of	of	ADP
ajst-25630	186	13	acute	acute	ADJ
ajst-25630	186	14	kidney	kidney	NOUN
ajst-25630	186	15	injury	injury	NOUN
ajst-25630	186	16	after	after	ADP
ajst-25630	186	17	cardiac	cardiac	ADJ
ajst-25630	186	18	surgery	surgery	NOUN
ajst-25630	187	1	[	[	X
ajst-25630	187	2	j	j	X
ajst-25630	187	3	]	]	X
ajst-25630	187	4	.	.	PUNCT
ajst-25630	188	1	china	china	PROPN
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ajst-25630	188	5	-	-	SYM
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ajst-25630	188	7	.	.	PUNCT
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ajst-25630	189	9	,	,	PUNCT
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ajst-25630	189	17	)	)	PUNCT
ajst-25630	189	18	.	.	PUNCT
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ajst-25630	190	5	between	between	ADP
ajst-25630	190	6	serum	serum	NOUN
ajst-25630	190	7	creatinine	creatinine	NOUN
ajst-25630	190	8	,	,	PUNCT
ajst-25630	190	9	urea	urea	NOUN
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ajst-25630	190	11	and	and	CCONJ
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ajst-25630	190	13	c	c	PROPN
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ajst-25630	190	15	and	and	CCONJ
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ajst-25630	191	1	[	[	X
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ajst-25630	191	4	.	.	PUNCT
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ajst-25630	192	5	-	-	SYM
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ajst-25630	192	7	.	.	PUNCT
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ajst-25630	193	17	,	,	PUNCT
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ajst-25630	193	21	(	(	PUNCT
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ajst-25630	193	23	)	)	PUNCT
ajst-25630	193	24	.	.	PUNCT
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ajst-25630	195	1	[	[	X
ajst-25630	195	2	j	j	X
ajst-25630	195	3	]	]	X
ajst-25630	195	4	.	.	PUNCT
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ajst-25630	196	4	,	,	PUNCT
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ajst-25630	196	6	-	-	SYM
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ajst-25630	196	8	.	.	PUNCT
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ajst-25630	197	5	,	,	PUNCT
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ajst-25630	197	8	,	,	PUNCT
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ajst-25630	198	1	(	(	PUNCT
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ajst-25630	198	3	)	)	PUNCT
ajst-25630	198	4	.	.	PUNCT
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ajst-25630	200	4	.	.	PUNCT
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ajst-25630	201	12	2(3	2(3	NUM
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ajst-25630	202	10	)	)	PUNCT
ajst-25630	202	11	.	.	PUNCT
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ajst-25630	203	6	kim-1	kim-1	SYM
ajst-25630	203	7	,	,	PUNCT
ajst-25630	203	8	cys	cys	PROPN
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ajst-25630	203	12	-	-	PUNCT
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ajst-25630	206	1	[	[	X
ajst-25630	206	2	14	14	NUM
ajst-25630	206	3	]	]	X
ajst-25630	206	4	zang	zang	PROPN
ajst-25630	206	5	,	,	PUNCT
ajst-25630	206	6	q.	q.	PROPN
ajst-25630	206	7	(	(	PUNCT
ajst-25630	206	8	2016	2016	NUM
ajst-25630	206	9	)	)	PUNCT
ajst-25630	206	10	.	.	PUNCT
ajst-25630	207	1	study	study	NOUN
ajst-25630	207	2	on	on	ADP
ajst-25630	207	3	the	the	DET
ajst-25630	207	4	relationship	relationship	NOUN
ajst-25630	207	5	between	between	ADP
ajst-25630	207	6	urinary	urinary	ADJ
ajst-25630	207	7	liver	liver	NOUN
ajst-25630	207	8	-	-	PUNCT
ajst-25630	207	9	type	type	NOUN
ajst-25630	207	10	fatty	fatty	NOUN
ajst-25630	207	11	acid	acid	NOUN
ajst-25630	207	12	binding	bind	VERB
ajst-25630	207	13	protein	protein	NOUN
ajst-25630	207	14	and	and	CCONJ
ajst-25630	207	15	inflammatory	inflammatory	ADJ
ajst-25630	207	16	response	response	NOUN
ajst-25630	207	17	in	in	ADP
ajst-25630	207	18	chronic	chronic	ADJ
ajst-25630	207	19	kidney	kidney	NOUN
ajst-25630	207	20	disease	disease	NOUN
ajst-25630	207	21	progression	progression	NOUN
ajst-25630	208	1	[	[	X
ajst-25630	208	2	d	d	X
ajst-25630	208	3	]	]	X
ajst-25630	208	4	.	.	PUNCT
ajst-25630	209	1	hebei	hebei	PROPN
ajst-25630	209	2	medical	medical	PROPN
ajst-25630	209	3	university	university	PROPN
ajst-25630	209	4	.	.	PUNCT
ajst-25630	210	1	[	[	X
ajst-25630	210	2	15	15	NUM
ajst-25630	210	3	]	]	X
ajst-25630	210	4	parikh	parikh	PROPN
ajst-25630	210	5	,	,	PUNCT
ajst-25630	210	6	c.r	c.r	PROPN
ajst-25630	210	7	.	.	PROPN
ajst-25630	210	8	,	,	PUNCT
ajst-25630	210	9	devarajan	devarajan	NOUN
ajst-25630	210	10	,	,	PUNCT
ajst-25630	210	11	p.	p.	NOUN
ajst-25630	210	12	,	,	PUNCT
ajst-25630	210	13	zappitelli	zappitelli	NOUN
ajst-25630	210	14	,	,	PUNCT
ajst-25630	210	15	m.	m.	NOUN
ajst-25630	210	16	,	,	PUNCT
ajst-25630	210	17	et	et	PROPN
ajst-25630	210	18	al	al	PROPN
ajst-25630	210	19	.	.	PUNCT
ajst-25630	211	1	(	(	PUNCT
ajst-25630	211	2	2011	2011	NUM
ajst-25630	211	3	)	)	PUNCT
ajst-25630	211	4	.	.	PUNCT
ajst-25630	212	1	postoperative	postoperative	ADJ
ajst-25630	212	2	biomarkers	biomarker	NOUN
ajst-25630	212	3	predict	predict	VERB
ajst-25630	212	4	acute	acute	ADJ
ajst-25630	212	5	kidney	kidney	PROPN
ajst-25630	212	6	injury	injury	NOUN
ajst-25630	212	7	and	and	CCONJ
ajst-25630	212	8	poor	poor	ADJ
ajst-25630	212	9	outcomes	outcome	NOUN
ajst-25630	212	10	after	after	ADP
ajst-25630	212	11	pediatric	pediatric	ADJ
ajst-25630	212	12	cardiac	cardiac	ADJ
ajst-25630	212	13	surgery	surgery	NOUN
ajst-25630	213	1	[	[	X
ajst-25630	213	2	j	j	X
ajst-25630	213	3	]	]	X
ajst-25630	213	4	.	.	PUNCT
ajst-25630	214	1	journal	journal	PROPN
ajst-25630	214	2	of	of	ADP
ajst-25630	214	3	the	the	DET
ajst-25630	214	4	american	american	ADJ
ajst-25630	214	5	society	society	NOUN
ajst-25630	214	6	of	of	ADP
ajst-25630	214	7	nephrology	nephrology	NOUN
ajst-25630	214	8	:	:	PUNCT
ajst-25630	214	9	jasn	jasn	NOUN
ajst-25630	214	10	,	,	PUNCT
ajst-25630	214	11	22(9	22(9	NUM
ajst-25630	214	12	)	)	PUNCT
ajst-25630	214	13	.	.	PUNCT
ajst-25630	215	1	[	[	X
ajst-25630	215	2	16	16	NUM
ajst-25630	215	3	]	]	X
ajst-25630	215	4	deng	deng	PROPN
ajst-25630	215	5	,	,	PUNCT
ajst-25630	215	6	n.	n.	PROPN
ajst-25630	215	7	,	,	PUNCT
ajst-25630	215	8	zhang	zhang	PROPN
ajst-25630	215	9	,	,	PUNCT
ajst-25630	215	10	d.f	d.f	PROPN
ajst-25630	215	11	.	.	PROPN
ajst-25630	215	12	(	(	PUNCT
ajst-25630	215	13	2015	2015	NUM
ajst-25630	215	14	)	)	PUNCT
ajst-25630	215	15	.	.	PUNCT
ajst-25630	216	1	research	research	NOUN
ajst-25630	216	2	progress	progress	NOUN
ajst-25630	216	3	of	of	ADP
ajst-25630	216	4	early	early	ADJ
ajst-25630	216	5	biological	biological	ADJ
ajst-25630	216	6	markers	marker	NOUN
ajst-25630	216	7	of	of	ADP
ajst-25630	216	8	acute	acute	PROPN
ajst-25630	216	9	kidney	kidney	NOUN
ajst-25630	216	10	injury	injury	NOUN
ajst-25630	216	11	after	after	ADP
ajst-25630	216	12	cardiac	cardiac	ADJ
ajst-25630	216	13	surgery	surgery	NOUN
ajst-25630	217	1	[	[	X
ajst-25630	217	2	j	j	X
ajst-25630	217	3	]	]	X
ajst-25630	217	4	.	.	PUNCT
ajst-25630	218	1	journal	journal	PROPN
ajst-25630	218	2	of	of	ADP
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ajst-25630	218	4	medicine	medicine	NOUN
ajst-25630	218	5	,	,	PUNCT
ajst-25630	218	6	31(22):3804	31(22):3804	NUM
ajst-25630	218	7	-	-	SYM
ajst-25630	218	8	3806	3806	NUM
ajst-25630	218	9	.	.	PUNCT
ajst-25630	219	1	222	222	NUM
ajst-25630	220	1	[	[	X
ajst-25630	220	2	17	17	NUM
ajst-25630	220	3	]	]	X
ajst-25630	220	4	yang	yang	PROPN
ajst-25630	220	5	,	,	PUNCT
ajst-25630	220	6	x.h	x.h	PROPN
ajst-25630	220	7	.	.	PROPN
ajst-25630	220	8	,	,	PUNCT
ajst-25630	220	9	sun	sun	PROPN
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ajst-25630	220	11	r.h	r.h	PROPN
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ajst-25630	220	13	(	(	PUNCT
ajst-25630	220	14	2023	2023	NUM
ajst-25630	220	15	)	)	PUNCT
ajst-25630	220	16	.	.	PUNCT
ajst-25630	221	1	biomarkers	biomarker	NOUN
ajst-25630	221	2	of	of	ADP
ajst-25630	221	3	acute	acute	ADJ
ajst-25630	221	4	kidney	kidney	NOUN
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ajst-25630	222	1	[	[	X
ajst-25630	222	2	j	j	X
ajst-25630	222	3	]	]	X
ajst-25630	222	4	.	.	PUNCT
ajst-25630	223	1	chinese	chinese	ADJ
ajst-25630	223	2	journal	journal	PROPN
ajst-25630	223	3	of	of	ADP
ajst-25630	223	4	practical	practical	ADJ
ajst-25630	223	5	internal	internal	ADJ
ajst-25630	223	6	medicine	medicine	NOUN
ajst-25630	223	7	,	,	PUNCT
ajst-25630	223	8	43(12):972	43(12):972	PROPN
ajst-25630	223	9	-	-	SYM
ajst-25630	223	10	977	977	NUM
ajst-25630	223	11	.	.	PUNCT
ajst-25630	224	1	doi:10.19538	doi:10.19538	PROPN
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ajst-25630	224	5	.	.	PUNCT
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ajst-25630	225	2	18	18	NUM
ajst-25630	225	3	]	]	X
ajst-25630	225	4	de	de	X
ajst-25630	225	5	velde	velde	PROPN
ajst-25630	225	6	,	,	PUNCT
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ajst-25630	225	8	.	.	PROPN
ajst-25630	225	9	,	,	PUNCT
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ajst-25630	225	11	,	,	PUNCT
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ajst-25630	225	13	,	,	PUNCT
ajst-25630	225	14	verhoeven	verhoeven	PROPN
ajst-25630	225	15	,	,	PUNCT
ajst-25630	225	16	y.j	y.j	PROPN
ajst-25630	225	17	.	.	PROPN
ajst-25630	225	18	,	,	PUNCT
ajst-25630	225	19	et	et	PROPN
ajst-25630	225	20	al	al	PROPN
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ajst-25630	225	22	(	(	PUNCT
ajst-25630	225	23	2022	2022	NUM
ajst-25630	225	24	)	)	PUNCT
ajst-25630	225	25	.	.	PUNCT
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ajst-25630	226	2	of	of	ADP
ajst-25630	226	3	acute	acute	ADJ
ajst-25630	226	4	kidney	kidney	NOUN
ajst-25630	226	5	injury	injury	NOUN
ajst-25630	226	6	after	after	ADP
ajst-25630	226	7	pediatric	pediatric	ADJ
ajst-25630	226	8	cardiac	cardiac	ADJ
ajst-25630	226	9	surgery	surgery	NOUN
ajst-25630	226	10	:	:	PUNCT
ajst-25630	226	11	a	a	DET
ajst-25630	226	12	meta	meta	ADJ
ajst-25630	226	13	-	-	PUNCT
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ajst-25630	226	15	of	of	ADP
ajst-25630	226	16	diagnostic	diagnostic	ADJ
ajst-25630	226	17	test	test	NOUN
ajst-25630	226	18	accuracy	accuracy	NOUN
ajst-25630	227	1	[	[	X
ajst-25630	227	2	j	j	X
ajst-25630	227	3	]	]	X
ajst-25630	227	4	.	.	PUNCT
ajst-25630	228	1	european	european	PROPN
ajst-25630	228	2	journal	journal	PROPN
ajst-25630	228	3	of	of	ADP
ajst-25630	228	4	pediatrics	pediatric	NOUN
ajst-25630	228	5	,	,	PUNCT
ajst-25630	228	6	181(5	181(5	NUM
ajst-25630	228	7	)	)	PUNCT
ajst-25630	228	8	.	.	PUNCT
ajst-25630	229	1	[	[	X
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ajst-25630	229	3	]	]	SYM
ajst-25630	229	4	yu	yu	PROPN
ajst-25630	229	5	,	,	PUNCT
ajst-25630	229	6	c.z	c.z	PROPN
ajst-25630	229	7	.	.	PROPN
ajst-25630	229	8	,	,	PUNCT
ajst-25630	229	9	cao	cao	PROPN
ajst-25630	229	10	,	,	PUNCT
ajst-25630	229	11	y.	y.	PROPN
ajst-25630	229	12	,	,	PUNCT
ajst-25630	229	13	chen	chen	PROPN
ajst-25630	229	14	,	,	PUNCT
ajst-25630	229	15	f.	f.	PROPN
ajst-25630	229	16	,	,	PUNCT
ajst-25630	229	17	et	et	PROPN
ajst-25630	229	18	al	al	PROPN
ajst-25630	229	19	.	.	PROPN
ajst-25630	230	1	(	(	PUNCT
ajst-25630	230	2	2013	2013	NUM
ajst-25630	230	3	)	)	PUNCT
ajst-25630	230	4	.	.	PUNCT
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ajst-25630	231	2	of	of	ADP
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ajst-25630	231	4	performance	performance	NOUN
ajst-25630	231	5	of	of	ADP
ajst-25630	231	6	glomerular	glomerular	ADJ
ajst-25630	231	7	filtration	filtration	NOUN
ajst-25630	231	8	rate	rate	NOUN
ajst-25630	231	9	estimation	estimation	NOUN
ajst-25630	231	10	equations	equation	NOUN
ajst-25630	232	1	[	[	X
ajst-25630	232	2	j	j	X
ajst-25630	232	3	]	]	X
ajst-25630	232	4	.	.	PUNCT
ajst-25630	233	1	journal	journal	PROPN
ajst-25630	233	2	of	of	ADP
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ajst-25630	233	4	jiao	jiao	PROPN
ajst-25630	233	5	tong	tong	PROPN
ajst-25630	233	6	university	university	PROPN
ajst-25630	233	7	(	(	PUNCT
ajst-25630	233	8	medical	medical	ADJ
ajst-25630	233	9	science	science	NOUN
ajst-25630	233	10	)	)	PUNCT
ajst-25630	233	11	,	,	PUNCT
ajst-25630	233	12	33(11):1496	33(11):1496	NUM
ajst-25630	233	13	-	-	SYM
ajst-25630	233	14	1500	1500	NUM
ajst-25630	233	15	.	.	PUNCT
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ajst-25630	234	3	]	]	X
ajst-25630	234	4	zeng	zeng	PROPN
ajst-25630	234	5	,	,	PUNCT
ajst-25630	234	6	x.h	x.h	PROPN
ajst-25630	234	7	.	.	PROPN
ajst-25630	234	8	,	,	PUNCT
ajst-25630	234	9	li	li	PROPN
ajst-25630	234	10	,	,	PUNCT
ajst-25630	234	11	z.x	z.x	PROPN
ajst-25630	234	12	.	.	PROPN
ajst-25630	234	13	,	,	PUNCT
ajst-25630	234	14	han	han	PROPN
ajst-25630	234	15	,	,	PUNCT
ajst-25630	234	16	p.x	p.x	PROPN
ajst-25630	234	17	.	.	PROPN
ajst-25630	234	18	,	,	PUNCT
ajst-25630	234	19	et	et	PROPN
ajst-25630	234	20	al	al	PROPN
ajst-25630	234	21	.	.	PUNCT
ajst-25630	234	22	(	(	PUNCT
ajst-25630	234	23	2015	2015	NUM
ajst-25630	234	24	)	)	PUNCT
ajst-25630	234	25	.	.	PUNCT
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ajst-25630	235	2	on	on	ADP
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ajst-25630	235	5	between	between	ADP
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ajst-25630	235	8	-	-	PUNCT
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ajst-25630	235	11	acid	acid	NOUN
ajst-25630	235	12	binding	bind	VERB
ajst-25630	235	13	protein	protein	NOUN
ajst-25630	235	14	and	and	CCONJ
ajst-25630	235	15	chronic	chronic	ADJ
ajst-25630	235	16	kidney	kidney	NOUN
ajst-25630	235	17	disease	disease	NOUN
ajst-25630	235	18	progression	progression	NOUN
ajst-25630	235	19	[	[	X
ajst-25630	235	20	j	j	X
ajst-25630	235	21	]	]	X
ajst-25630	235	22	.	.	PUNCT
ajst-25630	236	1	labeled	label	VERB
ajst-25630	236	2	immunoassays	immunoassay	NOUN
ajst-25630	236	3	&	&	CCONJ
ajst-25630	236	4	clinical	clinical	ADJ
ajst-25630	236	5	medicine	medicine	NOUN
ajst-25630	236	6	,	,	PUNCT
ajst-25630	236	7	22(07):672	22(07):672	NUM
ajst-25630	236	8	-	-	SYM
ajst-25630	236	9	674	674	NUM
ajst-25630	236	10	+	+	NOUN
ajst-25630	236	11	686	686	NUM
ajst-25630	236	12	.	.	PUNCT
ajst-25630	237	1	[	[	X
ajst-25630	237	2	21	21	NUM
ajst-25630	237	3	]	]	X
ajst-25630	237	4	zhang	zhang	PROPN
ajst-25630	237	5	,	,	PUNCT
ajst-25630	237	6	y.	y.	PROPN
ajst-25630	237	7	(	(	PUNCT
ajst-25630	237	8	2012	2012	NUM
ajst-25630	237	9	)	)	PUNCT
ajst-25630	237	10	.	.	PUNCT
ajst-25630	238	1	analysis	analysis	NOUN
ajst-25630	238	2	of	of	ADP
ajst-25630	238	3	influencing	influence	VERB
ajst-25630	238	4	factors	factor	NOUN
ajst-25630	238	5	of	of	ADP
ajst-25630	238	6	tubulointerstitial	tubulointerstitial	ADJ
ajst-25630	238	7	lesions	lesion	NOUN
ajst-25630	238	8	in	in	ADP
ajst-25630	238	9	lupus	lupus	ADJ
ajst-25630	238	10	nephritis	nephritis	NOUN
ajst-25630	238	11	and	and	CCONJ
ajst-25630	238	12	study	study	NOUN
ajst-25630	238	13	of	of	ADP
ajst-25630	238	14	urinary	urinary	ADJ
ajst-25630	238	15	markers	marker	NOUN
ajst-25630	239	1	[	[	X
ajst-25630	239	2	d	d	X
ajst-25630	239	3	]	]	X
ajst-25630	239	4	.	.	PUNCT
ajst-25630	240	1	chinese	chinese	PROPN
ajst-25630	240	2	pla	pla	PROPN
ajst-25630	240	3	medical	medical	PROPN
ajst-25630	240	4	school	school	NOUN
ajst-25630	240	5	.	.	PUNCT
ajst-25630	241	1	[	[	X
ajst-25630	241	2	22	22	NUM
ajst-25630	241	3	]	]	X
ajst-25630	241	4	mota	mota	NOUN
ajst-25630	241	5	,	,	PUNCT
ajst-25630	241	6	a.	a.	NOUN
ajst-25630	241	7	,	,	PUNCT
ajst-25630	241	8	khonsha	khonsha	PROPN
ajst-25630	241	9	,	,	PUNCT
ajst-25630	241	10	f.	f.	PROPN
ajst-25630	241	11	,	,	PUNCT
ajst-25630	241	12	nejabati	nejabati	PROPN
ajst-25630	241	13	,	,	PUNCT
ajst-25630	241	14	h.	h.	PROPN
ajst-25630	241	15	,	,	PUNCT
ajst-25630	241	16	et	et	PROPN
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ajst-25630	241	18	.	.	PUNCT
ajst-25630	242	1	(	(	PUNCT
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ajst-25630	242	3	)	)	PUNCT
ajst-25630	242	4	.	.	PUNCT
ajst-25630	243	1	biomarkers	biomarker	NOUN
ajst-25630	243	2	for	for	ADP
ajst-25630	243	3	diabetic	diabetic	ADJ
ajst-25630	243	4	nephropathy	nephropathy	NOUN
ajst-25630	243	5	with	with	ADP
ajst-25630	243	6	a	a	DET
ajst-25630	243	7	focus	focus	NOUN
ajst-25630	243	8	on	on	ADP
ajst-25630	243	9	kidney	kidney	NOUN
ajst-25630	243	10	injury	injury	PROPN
ajst-25630	243	11	molecule-1	molecule-1	PROPN
ajst-25630	243	12	(	(	PUNCT
ajst-25630	243	13	kim-1	kim-1	X
ajst-25630	243	14	)	)	PUNCT
ajst-25630	244	1	[	[	X
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ajst-25630	244	3	]	]	X
ajst-25630	244	4	.	.	PUNCT
ajst-25630	245	1	current	current	ADJ
ajst-25630	245	2	diabetes	diabetes	NOUN
ajst-25630	245	3	reviews	review	NOUN
ajst-25630	245	4	,	,	PUNCT
ajst-25630	245	5	20(1	20(1	NUM
ajst-25630	245	6	)	)	PUNCT
ajst-25630	245	7	.	.	PUNCT
ajst-25630	246	1	[	[	X
ajst-25630	246	2	23	23	NUM
ajst-25630	246	3	]	]	X
ajst-25630	246	4	meng	meng	PROPN
ajst-25630	246	5	,	,	PUNCT
ajst-25630	246	6	x.	x.	PROPN
ajst-25630	246	7	,	,	PUNCT
ajst-25630	246	8	wang	wang	PROPN
ajst-25630	246	9	,	,	PUNCT
ajst-25630	246	10	h.w	h.w	PROPN
ajst-25630	246	11	.	.	PUNCT
ajst-25630	246	12	(	(	PUNCT
ajst-25630	246	13	2024	2024	NUM
ajst-25630	246	14	)	)	PUNCT
ajst-25630	246	15	.	.	PUNCT
ajst-25630	247	1	research	research	NOUN
ajst-25630	247	2	progress	progress	NOUN
ajst-25630	247	3	on	on	ADP
ajst-25630	247	4	related	related	ADJ
ajst-25630	247	5	indicators	indicator	NOUN
ajst-25630	247	6	for	for	ADP
ajst-25630	247	7	early	early	ADJ
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ajst-25630	247	9	of	of	ADP
ajst-25630	247	10	diabetic	diabetic	ADJ
ajst-25630	247	11	nephropathy	nephropathy	NOUN
ajst-25630	247	12	[	[	X
ajst-25630	247	13	j	j	X
ajst-25630	247	14	]	]	X
ajst-25630	247	15	.	.	PUNCT
ajst-25630	248	1	journal	journal	PROPN
ajst-25630	248	2	of	of	ADP
ajst-25630	248	3	shenyang	shenyang	PROPN
ajst-25630	248	4	medical	medical	PROPN
ajst-25630	248	5	college	college	PROPN
ajst-25630	248	6	,	,	PUNCT
ajst-25630	248	7	26(02):188	26(02):188	PROPN
ajst-25630	248	8	-	-	SYM
ajst-25630	248	9	192	192	NUM
ajst-25630	248	10	+	+	NOUN
ajst-25630	248	11	199	199	NUM
ajst-25630	248	12	.	.	PUNCT
ajst-25630	249	1	doi	doi	NOUN
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ajst-25630	249	4	/	/	SYM
ajst-25630	249	5	j.cnki.1008	j.cnki.1008	NOUN
ajst-25630	249	6	-	-	PUNCT
ajst-25630	249	7	2344.2024.02.016	2344.2024.02.016	PROPN
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ajst-25630	250	3	]	]	PUNCT
ajst-25630	250	4	slocum	slocum	NOUN
ajst-25630	250	5	,	,	PUNCT
ajst-25630	250	6	l.j	l.j	PROPN
ajst-25630	250	7	.	.	PROPN
ajst-25630	250	8	,	,	PUNCT
ajst-25630	250	9	heung	heung	PROPN
ajst-25630	250	10	,	,	PUNCT
ajst-25630	250	11	m.	m.	NOUN
ajst-25630	250	12	,	,	PUNCT
ajst-25630	250	13	pennathur	pennathur	PROPN
ajst-25630	250	14	,	,	PUNCT
ajst-25630	250	15	s.	s.	PROPN
ajst-25630	250	16	(	(	PUNCT
ajst-25630	250	17	2012	2012	NUM
ajst-25630	250	18	)	)	PUNCT
ajst-25630	250	19	.	.	PUNCT
ajst-25630	251	1	marking	mark	VERB
ajst-25630	251	2	renal	renal	ADJ
ajst-25630	251	3	injury	injury	NOUN
ajst-25630	251	4	:	:	PUNCT
ajst-25630	251	5	can	can	AUX
ajst-25630	251	6	we	we	PRON
ajst-25630	251	7	move	move	VERB
ajst-25630	251	8	beyond	beyond	ADP
ajst-25630	251	9	serum	serum	NOUN
ajst-25630	251	10	creatinine	creatinine	NOUN
ajst-25630	251	11	?	?	PUNCT
ajst-25630	252	1	[	[	X
ajst-25630	252	2	j	j	X
ajst-25630	252	3	]	]	X
ajst-25630	252	4	.	.	PUNCT
ajst-25630	253	1	translational	translational	ADJ
ajst-25630	253	2	research	research	NOUN
ajst-25630	253	3	,	,	PUNCT
ajst-25630	253	4	159(4	159(4	NUM
ajst-25630	253	5	)	)	PUNCT
ajst-25630	253	6	.	.	PUNCT
ajst-25630	254	1	[	[	X
ajst-25630	254	2	25	25	NUM
ajst-25630	254	3	]	]	X
ajst-25630	254	4	che	che	X
ajst-25630	254	5	,	,	PUNCT
ajst-25630	254	6	x.j	x.j	PROPN
ajst-25630	254	7	.	.	PROPN
ajst-25630	254	8	(	(	PUNCT
ajst-25630	254	9	2019	2019	NUM
ajst-25630	254	10	)	)	PUNCT
ajst-25630	254	11	.	.	PUNCT
ajst-25630	255	1	analysis	analysis	NOUN
ajst-25630	255	2	of	of	ADP
ajst-25630	255	3	related	related	ADJ
ajst-25630	255	4	factors	factor	NOUN
ajst-25630	255	5	affecting	affect	VERB
ajst-25630	255	6	the	the	DET
ajst-25630	255	7	prognosis	prognosis	NOUN
ajst-25630	255	8	of	of	ADP
ajst-25630	255	9	allogeneic	allogeneic	ADJ
ajst-25630	255	10	kidney	kidney	NOUN
ajst-25630	255	11	transplantation	transplantation	NOUN
ajst-25630	255	12	and	and	CCONJ
ajst-25630	255	13	study	study	NOUN
ajst-25630	255	14	on	on	ADP
ajst-25630	255	15	the	the	DET
ajst-25630	255	16	mechanism	mechanism	NOUN
ajst-25630	255	17	of	of	ADP
ajst-25630	255	18	renal	renal	ADJ
ajst-25630	255	19	ischemia	ischemia	NOUN
ajst-25630	255	20	-	-	PUNCT
ajst-25630	255	21	reperfusion	reperfusion	NOUN
ajst-25630	255	22	injury	injury	NOUN
ajst-25630	256	1	[	[	X
ajst-25630	256	2	d	d	X
ajst-25630	256	3	]	]	X
ajst-25630	256	4	.	.	PUNCT
ajst-25630	257	1	shanghai	shanghai	PROPN
ajst-25630	257	2	jiao	jiao	PROPN
ajst-25630	257	3	tong	tong	PROPN
ajst-25630	257	4	university	university	PROPN
ajst-25630	257	5	.	.	PUNCT
ajst-25630	258	1	doi	doi	NOUN
ajst-25630	258	2	:	:	PUNCT
ajst-25630	258	3	10.27307	10.27307	NUM
ajst-25630	258	4	/	/	SYM
ajst-25630	258	5	d.	d.	PROPN
ajst-25630	258	6	cnki.gsjtu	cnki.gsjtu	PROPN
ajst-25630	258	7	.	.	PUNCT
ajst-25630	259	1	2019	2019	NUM
ajst-25630	259	2	.	.	PUNCT
ajst-25630	260	1	000	000	NUM
ajst-25630	261	1	666	666	NUM
ajst-25630	261	2	.	.	PUNCT
ajst-25630	262	1	[	[	X
ajst-25630	262	2	26	26	NUM
ajst-25630	262	3	]	]	SYM
ajst-25630	262	4	li	li	PROPN
ajst-25630	262	5	,	,	PUNCT
ajst-25630	262	6	j.	j.	PROPN
ajst-25630	262	7	,	,	PUNCT
ajst-25630	262	8	huang	huang	PROPN
ajst-25630	262	9	,	,	PUNCT
ajst-25630	262	10	h.t	h.t	PROPN
ajst-25630	262	11	.	.	PROPN
ajst-25630	262	12	,	,	PUNCT
ajst-25630	262	13	zhou	zhou	PROPN
ajst-25630	262	14	,	,	PUNCT
ajst-25630	262	15	g.p	g.p	PROPN
ajst-25630	262	16	.	.	PROPN
ajst-25630	262	17	(	(	PUNCT
ajst-25630	262	18	2017	2017	NUM
ajst-25630	262	19	)	)	PUNCT
ajst-25630	262	20	.	.	PUNCT
ajst-25630	263	1	a	a	DET
ajst-25630	263	2	retrospective	retrospective	ADJ
ajst-25630	263	3	study	study	NOUN
ajst-25630	263	4	on	on	ADP
ajst-25630	263	5	the	the	DET
ajst-25630	263	6	evaluation	evaluation	NOUN
ajst-25630	263	7	of	of	ADP
ajst-25630	263	8	acute	acute	ADJ
ajst-25630	263	9	kidney	kidney	NOUN
ajst-25630	263	10	injury	injury	NOUN
ajst-25630	263	11	caused	cause	VERB
ajst-25630	263	12	by	by	ADP
ajst-25630	263	13	vancomycin	vancomycin	PROPN
ajst-25630	263	14	in	in	ADP
ajst-25630	263	15	elderly	elderly	ADJ
ajst-25630	263	16	patients	patient	NOUN
ajst-25630	263	17	using	use	VERB
ajst-25630	263	18	serum	serum	NOUN
ajst-25630	263	19	cys	cys	PROPN
ajst-25630	263	20	-	-	PUNCT
ajst-25630	263	21	c	c	PROPN
ajst-25630	263	22	and	and	CCONJ
ajst-25630	263	23	urine	urine	NOUN
ajst-25630	263	24	kim-1	kim-1	PUNCT
ajst-25630	263	25	[	[	X
ajst-25630	263	26	j	j	X
ajst-25630	263	27	]	]	X
ajst-25630	263	28	.	.	PUNCT
ajst-25630	264	1	china	china	PROPN
ajst-25630	264	2	pharmacist	pharmacist	PROPN
ajst-25630	264	3	,	,	PUNCT
ajst-25630	264	4	20(12):2186	20(12):2186	PROPN
ajst-25630	264	5	-	-	SYM
ajst-25630	264	6	2189	2189	NUM
ajst-25630	264	7	.	.	PUNCT
ajst-25630	265	1	[	[	X
ajst-25630	265	2	27	27	NUM
ajst-25630	265	3	]	]	X
ajst-25630	265	4	wang	wang	PROPN
ajst-25630	265	5	,	,	PUNCT
ajst-25630	265	6	c.	c.	PROPN
ajst-25630	265	7	,	,	PUNCT
ajst-25630	265	8	bai	bai	PROPN
ajst-25630	265	9	,	,	PUNCT
ajst-25630	265	10	y.j	y.j	PROPN
ajst-25630	265	11	.	.	PROPN
ajst-25630	265	12	,	,	PUNCT
ajst-25630	265	13	zhou	zhou	PROPN
ajst-25630	265	14	,	,	PUNCT
ajst-25630	265	15	x.b	x.b	PROPN
ajst-25630	265	16	.	.	PROPN
ajst-25630	265	17	,	,	PUNCT
ajst-25630	265	18	et	et	PROPN
ajst-25630	265	19	al	al	PROPN
ajst-25630	265	20	.	.	PROPN
ajst-25630	265	21	(	(	PUNCT
ajst-25630	265	22	2021	2021	NUM
ajst-25630	265	23	)	)	PUNCT
ajst-25630	265	24	.	.	PUNCT
ajst-25630	266	1	research	research	NOUN
ajst-25630	266	2	progress	progress	NOUN
ajst-25630	266	3	of	of	ADP
ajst-25630	266	4	urinary	urinary	ADJ
ajst-25630	266	5	ngal	ngal	ADV
ajst-25630	266	6	as	as	ADP
ajst-25630	266	7	a	a	DET
ajst-25630	266	8	biomarker	biomarker	NOUN
ajst-25630	266	9	of	of	ADP
ajst-25630	266	10	drug	drug	NOUN
ajst-25630	266	11	-	-	PUNCT
ajst-25630	266	12	induced	induce	VERB
ajst-25630	266	13	acute	acute	ADJ
ajst-25630	266	14	nephrotoxicity	nephrotoxicity	NOUN
ajst-25630	267	1	[	[	X
ajst-25630	267	2	j	j	X
ajst-25630	267	3	]	]	X
ajst-25630	267	4	.	.	PUNCT
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ajst-25630	268	2	evaluation	evaluation	NOUN
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ajst-25630	268	4	,	,	PUNCT
ajst-25630	268	5	44(08	44(08	NUM
ajst-25630	268	6	):	):	PUNCT
ajst-25630	268	7	1806	1806	NUM
ajst-25630	268	8	-	-	SYM
ajst-25630	268	9	1810	1810	NUM
ajst-25630	268	10	.	.	PUNCT
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ajst-25630	269	2	28	28	NUM
ajst-25630	269	3	]	]	X
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ajst-25630	269	6	j.m	j.m	PROPN
ajst-25630	269	7	.	.	PROPN
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ajst-25630	269	10	,	,	PUNCT
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ajst-25630	269	12	,	,	PUNCT
ajst-25630	269	13	alge	alge	PROPN
ajst-25630	269	14	,	,	PUNCT
ajst-25630	269	15	j.l	j.l	PROPN
ajst-25630	269	16	.	.	PROPN
ajst-25630	269	17	,	,	PUNCT
ajst-25630	269	18	et	et	PROPN
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ajst-25630	269	21	(	(	PUNCT
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ajst-25630	269	23	)	)	PUNCT
ajst-25630	269	24	.	.	PUNCT
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ajst-25630	270	3	32	32	NUM
ajst-25630	270	4	urine	urine	NOUN
ajst-25630	270	5	biomarkers	biomarker	NOUN
ajst-25630	270	6	to	to	PART
ajst-25630	270	7	predict	predict	VERB
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ajst-25630	270	9	progression	progression	NOUN
ajst-25630	270	10	of	of	ADP
ajst-25630	270	11	acute	acute	ADJ
ajst-25630	270	12	kidney	kidney	NOUN
ajst-25630	270	13	injury	injury	NOUN
ajst-25630	270	14	after	after	ADP
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ajst-25630	270	16	surgery	surgery	NOUN
ajst-25630	271	1	[	[	X
ajst-25630	271	2	j	j	X
ajst-25630	271	3	]	]	X
ajst-25630	271	4	.	.	PUNCT
ajst-25630	272	1	kidney	kidney	PROPN
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ajst-25630	272	3	,	,	PUNCT
ajst-25630	272	4	85(2	85(2	NUM
ajst-25630	272	5	)	)	PUNCT
ajst-25630	272	6	.	.	PUNCT
ajst-25630	273	1	[	[	X
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ajst-25630	273	3	]	]	X
ajst-25630	273	4	zhao	zhao	X
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ajst-25630	273	7	(	(	PUNCT
ajst-25630	273	8	2020	2020	NUM
ajst-25630	273	9	)	)	PUNCT
ajst-25630	273	10	.	.	PUNCT
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ajst-25630	274	4	kidney	kidney	NOUN
ajst-25630	274	5	disease	disease	NOUN
ajst-25630	274	6	-	-	PUNCT
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ajst-25630	274	11	of	of	ADP
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ajst-25630	274	14	[	[	X
ajst-25630	274	15	d	d	X
ajst-25630	274	16	]	]	X
ajst-25630	274	17	.	.	PUNCT
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ajst-25630	275	2	medical	medical	PROPN
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ajst-25630	275	4	.	.	PUNCT
ajst-25630	276	1	doi:10.27366/	doi:10.27366/	VERB
ajst-25630	276	2	d.cnki	d.cnki	PROPN
ajst-25630	276	3	.	.	PUNCT
ajst-25630	277	1	gtyku	gtyku	PROPN
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ajst-25630	278	1	2020.000379	2020.000379	NOUN
ajst-25630	278	2	.	.	PUNCT
ajst-25630	279	1	[	[	X
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ajst-25630	279	6	z.	z.	PROPN
ajst-25630	279	7	,	,	PUNCT
ajst-25630	279	8	zhang	zhang	PROPN
ajst-25630	279	9	,	,	PUNCT
ajst-25630	279	10	j.	j.	PROPN
ajst-25630	279	11	,	,	PUNCT
ajst-25630	279	12	tang	tang	PROPN
ajst-25630	279	13	,	,	PUNCT
ajst-25630	279	14	l.p	l.p	PROPN
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ajst-25630	279	18	)	)	PUNCT
ajst-25630	279	19	.	.	PUNCT
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ajst-25630	280	3	serum	serum	PROPN
ajst-25630	280	4	rbp	rbp	PROPN
ajst-25630	280	5	,	,	PUNCT
ajst-25630	280	6	nefa	nefa	PROPN
ajst-25630	280	7	,	,	PUNCT
ajst-25630	280	8	fkn	fkn	PROPN
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ajst-25630	280	12	excretion	excretion	NOUN
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ajst-25630	280	14	glomerular	glomerular	ADJ
ajst-25630	280	15	filtration	filtration	NOUN
ajst-25630	280	16	function	function	NOUN
ajst-25630	280	17	damage	damage	NOUN
ajst-25630	280	18	in	in	ADP
ajst-25630	280	19	early	early	ADJ
ajst-25630	280	20	diabetic	diabetic	ADJ
ajst-25630	280	21	nephropathy	nephropathy	ADJ
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ajst-25630	280	23	[	[	X
ajst-25630	280	24	j	j	X
ajst-25630	280	25	]	]	X
ajst-25630	280	26	.	.	PUNCT
ajst-25630	281	1	journal	journal	PROPN
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ajst-25630	281	6	,	,	PUNCT
ajst-25630	281	7	22(23):2822	22(23):2822	NOUN
ajst-25630	281	8	-	-	SYM
ajst-25630	281	9	2825	2825	NUM
ajst-25630	281	10	.	.	PUNCT
ajst-25630	282	1	doi	doi	NOUN
ajst-25630	282	2	:	:	PUNCT
ajst-25630	282	3	10.13210	10.13210	NUM
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ajst-25630	282	6	.	.	PUNCT
ajst-25630	283	1	[	[	X
ajst-25630	283	2	31	31	NUM
ajst-25630	283	3	]	]	X
ajst-25630	283	4	zhou	zhou	PROPN
ajst-25630	283	5	,	,	PUNCT
ajst-25630	283	6	x.	x.	PROPN
ajst-25630	283	7	,	,	PUNCT
ajst-25630	283	8	zhang	zhang	PROPN
ajst-25630	283	9	,	,	PUNCT
ajst-25630	283	10	h.	h.	PROPN
ajst-25630	283	11	,	,	PUNCT
ajst-25630	283	12	liu	liu	PROPN
ajst-25630	283	13	,	,	PUNCT
ajst-25630	283	14	y.	y.	PROPN
ajst-25630	283	15	(	(	PUNCT
ajst-25630	283	16	2017	2017	NUM
ajst-25630	283	17	)	)	PUNCT
ajst-25630	283	18	.	.	PUNCT
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ajst-25630	284	2	detection	detection	NOUN
ajst-25630	284	3	of	of	ADP
ajst-25630	284	4	urinary	urinary	ADJ
ajst-25630	284	5	micro	micro	PROPN
ajst-25630	284	6	albumin	albumin	PROPN
ajst-25630	284	7	,	,	PUNCT
ajst-25630	284	8	α1	α1	PROPN
ajst-25630	284	9	-	-	PUNCT
ajst-25630	284	10	microglobulin	microglobulin	PROPN
ajst-25630	284	11	and	and	CCONJ
ajst-25630	284	12	n	n	CCONJ
ajst-25630	284	13	-	-	PUNCT
ajst-25630	284	14	acetyl	acetyl	NOUN
ajst-25630	284	15	-	-	PUNCT
ajst-25630	284	16	β	β	NOUN
ajst-25630	284	17	-	-	NOUN
ajst-25630	284	18	dglucosaminidase	dglucosaminidase	NOUN
ajst-25630	284	19	in	in	ADP
ajst-25630	284	20	the	the	DET
ajst-25630	284	21	early	early	ADJ
ajst-25630	284	22	diagnosis	diagnosis	NOUN
ajst-25630	284	23	of	of	ADP
ajst-25630	284	24	diabetic	diabetic	ADJ
ajst-25630	284	25	nephropathy	nephropathy	NOUN
ajst-25630	284	26	[	[	X
ajst-25630	284	27	j	j	X
ajst-25630	284	28	]	]	X
ajst-25630	284	29	.	.	PUNCT
ajst-25630	285	1	pakistan	pakistan	PROPN
ajst-25630	285	2	journal	journal	PROPN
ajst-25630	285	3	of	of	ADP
ajst-25630	285	4	medical	medical	ADJ
ajst-25630	285	5	sciences	sciences	PROPN
ajst-25630	285	6	,	,	PUNCT
ajst-25630	285	7	33(6	33(6	NUM
ajst-25630	285	8	)	)	PUNCT
ajst-25630	285	9	.	.	PUNCT
ajst-25630	286	1	[	[	X
ajst-25630	286	2	32	32	NUM
ajst-25630	286	3	]	]	SYM
ajst-25630	286	4	yang	yang	PROPN
ajst-25630	286	5	,	,	PUNCT
ajst-25630	286	6	z.x	z.x	PROPN
ajst-25630	286	7	.	.	PROPN
ajst-25630	286	8	,	,	PUNCT
ajst-25630	286	9	zhang	zhang	PROPN
ajst-25630	286	10	,	,	PUNCT
ajst-25630	286	11	y.g	y.g	PROPN
ajst-25630	286	12	.	.	PROPN
ajst-25630	286	13	,	,	PUNCT
ajst-25630	286	14	zhang	zhang	PROPN
ajst-25630	286	15	,	,	PUNCT
ajst-25630	286	16	s.y	s.y	PROPN
ajst-25630	286	17	.	.	PROPN
ajst-25630	286	18	,	,	PUNCT
ajst-25630	286	19	et	et	PROPN
ajst-25630	286	20	al	al	PROPN
ajst-25630	286	21	.	.	PROPN
ajst-25630	286	22	(	(	PUNCT
ajst-25630	286	23	2021	2021	NUM
ajst-25630	286	24	)	)	PUNCT
ajst-25630	286	25	.	.	PUNCT
ajst-25630	287	1	analysis	analysis	NOUN
ajst-25630	287	2	of	of	ADP
ajst-25630	287	3	the	the	DET
ajst-25630	287	4	relationship	relationship	NOUN
ajst-25630	287	5	between	between	ADP
ajst-25630	287	6	serum	serum	NOUN
ajst-25630	287	7	d	d	PROPN
ajst-25630	287	8	-	-	PUNCT
ajst-25630	287	9	d	d	PROPN
ajst-25630	287	10	,	,	PUNCT
ajst-25630	287	11	kim-1	kim-1	PUNCT
ajst-25630	287	12	and	and	CCONJ
ajst-25630	287	13	urine	urine	PROPN
ajst-25630	287	14	rbp	rbp	PROPN
ajst-25630	287	15	levels	level	NOUN
ajst-25630	287	16	and	and	CCONJ
ajst-25630	287	17	disease	disease	NOUN
ajst-25630	287	18	severity	severity	NOUN
ajst-25630	287	19	and	and	CCONJ
ajst-25630	287	20	homa	homa	NOUN
ajst-25630	287	21	-	-	PUNCT
ajst-25630	287	22	ir	ir	PROPN
ajst-25630	287	23	in	in	ADP
ajst-25630	287	24	patients	patient	NOUN
ajst-25630	287	25	with	with	ADP
ajst-25630	287	26	diabetic	diabetic	ADJ
ajst-25630	287	27	nephropathy	nephropathy	NOUN
ajst-25630	287	28	[	[	X
ajst-25630	287	29	j	j	X
ajst-25630	287	30	]	]	X
ajst-25630	287	31	.	.	PUNCT
ajst-25630	288	1	labeled	label	VERB
ajst-25630	288	2	immunoassays	immunoassay	NOUN
ajst-25630	288	3	&	&	CCONJ
ajst-25630	288	4	clinical	clinical	ADJ
ajst-25630	288	5	medicine	medicine	NOUN
ajst-25630	288	6	,	,	PUNCT
ajst-25630	288	7	28(08):1349	28(08):1349	NUM
ajst-25630	288	8	-	-	SYM
ajst-25630	288	9	1352	1352	NUM
ajst-25630	288	10	+	+	NOUN
ajst-25630	288	11	1360	1360	NUM
ajst-25630	288	12	.	.	PUNCT