id	sid	tid	token	lemma	pos
ajst-27318	1	1	academic	academic	ADJ
ajst-27318	1	2	journal	journal	NOUN
ajst-27318	1	3	of	of	ADP
ajst-27318	1	4	science	science	NOUN
ajst-27318	1	5	and	and	CCONJ
ajst-27318	1	6	technology	technology	NOUN
ajst-27318	1	7	issn	issn	NOUN
ajst-27318	1	8	:	:	PUNCT
ajst-27318	1	9	2771	2771	NUM
ajst-27318	1	10	-	-	SYM
ajst-27318	1	11	3032	3032	NUM
ajst-27318	1	12	|	|	NOUN
ajst-27318	1	13	vol	vol	NOUN
ajst-27318	1	14	.	.	PROPN
ajst-27318	1	15	13	13	NUM
ajst-27318	1	16	,	,	PUNCT
ajst-27318	1	17	no	no	INTJ
ajst-27318	1	18	.	.	NOUN
ajst-27318	1	19	2	2	NUM
ajst-27318	1	20	,	,	PUNCT
ajst-27318	1	21	2024	2024	NUM
ajst-27318	1	22	74	74	NUM
ajst-27318	1	23	effects	effect	NOUN
ajst-27318	1	24	of	of	ADP
ajst-27318	1	25	radix	radix	NOUN
ajst-27318	1	26	achyrandii	achyrandii	NOUN
ajst-27318	1	27	polysaccharide	polysaccharide	ADV
ajst-27318	1	28	on	on	ADP
ajst-27318	1	29	cartilage	cartilage	NOUN
ajst-27318	1	30	morphology	morphology	NOUN
ajst-27318	1	31	of	of	ADP
ajst-27318	1	32	knee	knee	NOUN
ajst-27318	1	33	osteoarthritis	osteoarthritis	NOUN
ajst-27318	1	34	in	in	ADP
ajst-27318	1	35	obese	obese	ADJ
ajst-27318	1	36	mice	mouse	NOUN
ajst-27318	1	37	induced	induce	VERB
ajst-27318	1	38	by	by	ADP
ajst-27318	1	39	high‐fat	high‐fat	PROPN
ajst-27318	1	40	diet	diet	PROPN
ajst-27318	1	41	jiaqi	jiaqi	PROPN
ajst-27318	1	42	zhang1	zhang1	PROPN
ajst-27318	1	43	,	,	PUNCT
ajst-27318	1	44	yaxuan	yaxuan	PROPN
ajst-27318	1	45	deng1	deng1	PROPN
ajst-27318	1	46	,	,	PUNCT
ajst-27318	1	47	jiangyuan	jiangyuan	PROPN
ajst-27318	1	48	chen1	chen1	PROPN
ajst-27318	1	49	,	,	PUNCT
ajst-27318	1	50	ying	ying	PROPN
ajst-27318	1	51	zhai1	zhai1	PROPN
ajst-27318	1	52	,	,	PUNCT
ajst-27318	1	53	fuyan	fuyan	PROPN
ajst-27318	1	54	wang1	wang1	PROPN
ajst-27318	1	55	,	,	PUNCT
ajst-27318	1	56	fahu	fahu	PROPN
ajst-27318	1	57	yuan1	yuan1	PROPN
ajst-27318	1	58	,	,	PUNCT
ajst-27318	1	59	*	*	PUNCT
ajst-27318	2	1	1school	1school	NUM
ajst-27318	2	2	of	of	ADP
ajst-27318	2	3	medicine	medicine	NOUN
ajst-27318	2	4	,	,	PUNCT
ajst-27318	2	5	jianghan	jianghan	PROPN
ajst-27318	2	6	university	university	PROPN
ajst-27318	2	7	,	,	PUNCT
ajst-27318	2	8	wuhan	wuhan	PROPN
ajst-27318	2	9	,	,	PUNCT
ajst-27318	2	10	china	china	PROPN
ajst-27318	2	11	*	*	PUNCT
ajst-27318	2	12	corresponding	correspond	VERB
ajst-27318	2	13	author	author	NOUN
ajst-27318	2	14	:	:	PUNCT
ajst-27318	2	15	3135213586@qq.com	3135213586@qq.com	NUM
ajst-27318	2	16	abstract	abstract	NOUN
ajst-27318	2	17	:	:	PUNCT
ajst-27318	2	18	objective	objective	NOUN
ajst-27318	2	19	:	:	PUNCT
ajst-27318	2	20	to	to	PART
ajst-27318	2	21	study	study	VERB
ajst-27318	2	22	the	the	DET
ajst-27318	2	23	pathological	pathological	ADJ
ajst-27318	2	24	changes	change	NOUN
ajst-27318	2	25	of	of	ADP
ajst-27318	2	26	articular	articular	ADJ
ajst-27318	2	27	cartilage	cartilage	NOUN
ajst-27318	2	28	in	in	ADP
ajst-27318	2	29	the	the	DET
ajst-27318	2	30	process	process	NOUN
ajst-27318	2	31	of	of	ADP
ajst-27318	2	32	osteoarthritis	osteoarthritis	NOUN
ajst-27318	2	33	induced	induce	VERB
ajst-27318	2	34	by	by	ADP
ajst-27318	2	35	highfat	highfat	NOUN
ajst-27318	2	36	diet	diet	NOUN
ajst-27318	2	37	and	and	CCONJ
ajst-27318	2	38	the	the	DET
ajst-27318	2	39	mechanism	mechanism	NOUN
ajst-27318	2	40	of	of	ADP
ajst-27318	2	41	radix	radix	NOUN
ajst-27318	2	42	achyrandii	achyrandii	NOUN
ajst-27318	2	43	polysaccharide	polysaccharide	ADV
ajst-27318	2	44	on	on	ADP
ajst-27318	2	45	osteoarthritis	osteoarthritis	NOUN
ajst-27318	2	46	cartilage	cartilage	NOUN
ajst-27318	2	47	,	,	PUNCT
ajst-27318	2	48	and	and	CCONJ
ajst-27318	2	49	to	to	PART
ajst-27318	2	50	explore	explore	VERB
ajst-27318	2	51	the	the	DET
ajst-27318	2	52	protective	protective	ADJ
ajst-27318	2	53	effect	effect	NOUN
ajst-27318	2	54	of	of	ADP
ajst-27318	2	55	achyrannosus	achyrannosus	PROPN
ajst-27318	2	56	achyrannosus	achyrannosus	NOUN
ajst-27318	2	57	polysaccharide	polysaccharide	NOUN
ajst-27318	2	58	on	on	ADP
ajst-27318	2	59	knee	knee	NOUN
ajst-27318	2	60	osteoarthritis	osteoarthritis	NOUN
ajst-27318	2	61	cartilage	cartilage	NOUN
ajst-27318	2	62	,	,	PUNCT
ajst-27318	2	63	so	so	SCONJ
ajst-27318	2	64	as	as	SCONJ
ajst-27318	2	65	to	to	PART
ajst-27318	2	66	provide	provide	VERB
ajst-27318	2	67	effective	effective	ADJ
ajst-27318	2	68	experimental	experimental	ADJ
ajst-27318	2	69	evidence	evidence	NOUN
ajst-27318	2	70	for	for	ADP
ajst-27318	2	71	clinical	clinical	ADJ
ajst-27318	2	72	treatment	treatment	NOUN
ajst-27318	2	73	of	of	ADP
ajst-27318	2	74	knee	knee	NOUN
ajst-27318	2	75	osteoarthritis	osteoarthritis	NOUN
ajst-27318	2	76	.	.	PUNCT
ajst-27318	3	1	methods	method	NOUN
ajst-27318	3	2	:	:	PUNCT
ajst-27318	3	3	oa	oa	PROPN
ajst-27318	3	4	model	model	NOUN
ajst-27318	3	5	induced	induce	VERB
ajst-27318	3	6	by	by	ADP
ajst-27318	3	7	anterior	anterior	ADJ
ajst-27318	3	8	cruciate	cruciate	NOUN
ajst-27318	3	9	ligament	ligament	NOUN
ajst-27318	3	10	transection	transection	NOUN
ajst-27318	3	11	was	be	AUX
ajst-27318	3	12	established	establish	VERB
ajst-27318	3	13	in	in	ADP
ajst-27318	3	14	obese	obese	ADJ
ajst-27318	3	15	rats	rat	NOUN
ajst-27318	3	16	induced	induce	VERB
ajst-27318	3	17	by	by	ADP
ajst-27318	3	18	high	high	ADJ
ajst-27318	3	19	-	-	PUNCT
ajst-27318	3	20	fat	fat	NOUN
ajst-27318	3	21	diet	diet	NOUN
ajst-27318	3	22	.	.	PUNCT
ajst-27318	4	1	thirty	thirty	NUM
ajst-27318	4	2	c57bl/6	c57bl/6	NOUN
ajst-27318	4	3	j	j	PROPN
ajst-27318	4	4	mice	mouse	NOUN
ajst-27318	4	5	were	be	AUX
ajst-27318	4	6	randomly	randomly	ADV
ajst-27318	4	7	divided	divide	VERB
ajst-27318	4	8	into	into	ADP
ajst-27318	4	9	normal	normal	ADJ
ajst-27318	4	10	diet	diet	NOUN
ajst-27318	4	11	group	group	NOUN
ajst-27318	4	12	(	(	PUNCT
ajst-27318	4	13	con	con	PROPN
ajst-27318	4	14	)	)	PUNCT
ajst-27318	4	15	,	,	PUNCT
ajst-27318	4	16	high	high	ADJ
ajst-27318	4	17	fat	fat	ADJ
ajst-27318	4	18	diet	diet	PROPN
ajst-27318	4	19	group	group	NOUN
ajst-27318	4	20	(	(	PUNCT
ajst-27318	4	21	oa	oa	PROPN
ajst-27318	4	22	)	)	PUNCT
ajst-27318	4	23	and	and	CCONJ
ajst-27318	4	24	high	high	ADJ
ajst-27318	4	25	fat	fat	ADJ
ajst-27318	4	26	diet	diet	PROPN
ajst-27318	4	27	plus	plus	CCONJ
ajst-27318	4	28	radix	radix	NOUN
ajst-27318	4	29	achyrandii	achyrandii	NOUN
ajst-27318	4	30	polysaccharide	polysaccharide	NOUN
ajst-27318	4	31	(	(	PUNCT
ajst-27318	4	32	rap	rap	NOUN
ajst-27318	4	33	)	)	PUNCT
ajst-27318	4	34	.	.	PUNCT
ajst-27318	5	1	the	the	DET
ajst-27318	5	2	con	con	PROPN
ajst-27318	5	3	group	group	NOUN
ajst-27318	5	4	was	be	AUX
ajst-27318	5	5	fed	feed	VERB
ajst-27318	5	6	with	with	ADP
ajst-27318	5	7	a	a	DET
ajst-27318	5	8	basal	basal	ADJ
ajst-27318	5	9	diet	diet	NOUN
ajst-27318	5	10	,	,	PUNCT
ajst-27318	5	11	and	and	CCONJ
ajst-27318	5	12	the	the	DET
ajst-27318	5	13	oa	oa	PROPN
ajst-27318	5	14	and	and	CCONJ
ajst-27318	5	15	raa	raa	NOUN
ajst-27318	5	16	groups	group	NOUN
ajst-27318	5	17	were	be	AUX
ajst-27318	5	18	fed	feed	VERB
ajst-27318	5	19	with	with	ADP
ajst-27318	5	20	a	a	DET
ajst-27318	5	21	high	high	ADJ
ajst-27318	5	22	-	-	PUNCT
ajst-27318	5	23	fat	fat	NOUN
ajst-27318	5	24	diet	diet	NOUN
ajst-27318	5	25	.	.	PUNCT
ajst-27318	6	1	after	after	ADP
ajst-27318	6	2	8	8	NUM
ajst-27318	6	3	weeks	week	NOUN
ajst-27318	6	4	of	of	ADP
ajst-27318	6	5	feeding	feeding	NOUN
ajst-27318	6	6	,	,	PUNCT
ajst-27318	6	7	the	the	DET
ajst-27318	6	8	rap	rap	NOUN
ajst-27318	6	9	group	group	NOUN
ajst-27318	6	10	was	be	AUX
ajst-27318	6	11	treated	treat	VERB
ajst-27318	6	12	with	with	ADP
ajst-27318	6	13	polysaccharide	polysaccharide	NOUN
ajst-27318	6	14	(	(	PUNCT
ajst-27318	6	15	200	200	NUM
ajst-27318	6	16	mg	mg	PROPN
ajst-27318	6	17	/	/	SYM
ajst-27318	6	18	kg·d	kg·d	PROPN
ajst-27318	6	19	)	)	PUNCT
ajst-27318	6	20	by	by	ADP
ajst-27318	6	21	gavage	gavage	NOUN
ajst-27318	6	22	once	once	ADV
ajst-27318	6	23	a	a	DET
ajst-27318	6	24	day	day	NOUN
ajst-27318	6	25	for	for	ADP
ajst-27318	6	26	4	4	NUM
ajst-27318	6	27	weeks	week	NOUN
ajst-27318	6	28	,	,	PUNCT
ajst-27318	6	29	and	and	CCONJ
ajst-27318	6	30	the	the	DET
ajst-27318	6	31	blank	blank	ADJ
ajst-27318	6	32	group	group	NOUN
ajst-27318	6	33	and	and	CCONJ
ajst-27318	6	34	the	the	DET
ajst-27318	6	35	model	model	NOUN
ajst-27318	6	36	group	group	NOUN
ajst-27318	6	37	were	be	AUX
ajst-27318	6	38	given	give	VERB
ajst-27318	6	39	the	the	DET
ajst-27318	6	40	same	same	ADJ
ajst-27318	6	41	volume	volume	NOUN
ajst-27318	6	42	of	of	ADP
ajst-27318	6	43	normal	normal	ADJ
ajst-27318	6	44	saline	saline	NOUN
ajst-27318	6	45	.	.	PUNCT
ajst-27318	7	1	at	at	ADP
ajst-27318	7	2	the	the	DET
ajst-27318	7	3	end	end	NOUN
ajst-27318	7	4	of	of	ADP
ajst-27318	7	5	the	the	DET
ajst-27318	7	6	experiment	experiment	NOUN
ajst-27318	7	7	,	,	PUNCT
ajst-27318	7	8	the	the	DET
ajst-27318	7	9	serum	serum	NOUN
ajst-27318	7	10	levels	level	NOUN
ajst-27318	7	11	of	of	ADP
ajst-27318	7	12	tg	tg	PROPN
ajst-27318	7	13	,	,	PUNCT
ajst-27318	7	14	tc	tc	NOUN
ajst-27318	7	15	,	,	PUNCT
ajst-27318	7	16	hdl	hdl	PROPN
ajst-27318	7	17	-	-	PUNCT
ajst-27318	7	18	c	c	PROPN
ajst-27318	7	19	and	and	CCONJ
ajst-27318	7	20	ldl	ldl	PROPN
ajst-27318	7	21	-	-	PUNCT
ajst-27318	7	22	c	c	PROPN
ajst-27318	7	23	were	be	AUX
ajst-27318	7	24	detected	detect	VERB
ajst-27318	7	25	by	by	ADP
ajst-27318	7	26	biochemical	biochemical	ADJ
ajst-27318	7	27	methods	method	NOUN
ajst-27318	7	28	.	.	PUNCT
ajst-27318	8	1	the	the	DET
ajst-27318	8	2	activity	activity	NOUN
ajst-27318	8	3	of	of	ADP
ajst-27318	8	4	superoxide	superoxide	NOUN
ajst-27318	8	5	dismutase	dismutase	NOUN
ajst-27318	8	6	(	(	PUNCT
ajst-27318	8	7	sod	sod	NOUN
ajst-27318	8	8	)	)	PUNCT
ajst-27318	8	9	and	and	CCONJ
ajst-27318	8	10	the	the	DET
ajst-27318	8	11	levels	level	NOUN
ajst-27318	8	12	of	of	ADP
ajst-27318	8	13	malondialdehyde	malondialdehyde	PROPN
ajst-27318	8	14	(	(	PUNCT
ajst-27318	8	15	mda	mda	PROPN
ajst-27318	8	16	)	)	PUNCT
ajst-27318	8	17	,	,	PUNCT
ajst-27318	8	18	tumor	tumor	NOUN
ajst-27318	8	19	necrosis	necrosis	NOUN
ajst-27318	8	20	factor	factor	NOUN
ajst-27318	8	21	-	-	PUNCT
ajst-27318	8	22	α	α	NOUN
ajst-27318	8	23	(	(	PUNCT
ajst-27318	8	24	tnfα	tnfα	NOUN
ajst-27318	8	25	)	)	PUNCT
ajst-27318	8	26	and	and	CCONJ
ajst-27318	8	27	interleukin-1β	interleukin-1β	NOUN
ajst-27318	8	28	(	(	PUNCT
ajst-27318	8	29	il-1β	il-1β	PROPN
ajst-27318	8	30	)	)	PUNCT
ajst-27318	8	31	were	be	AUX
ajst-27318	8	32	measured	measure	VERB
ajst-27318	8	33	by	by	ADP
ajst-27318	8	34	elisa	elisa	PROPN
ajst-27318	8	35	.	.	PUNCT
ajst-27318	9	1	h&e	h&e	PROPN
ajst-27318	9	2	staining	stain	VERB
ajst-27318	9	3	was	be	AUX
ajst-27318	9	4	used	use	VERB
ajst-27318	9	5	to	to	PART
ajst-27318	9	6	observe	observe	VERB
ajst-27318	9	7	the	the	DET
ajst-27318	9	8	pathological	pathological	ADJ
ajst-27318	9	9	changes	change	NOUN
ajst-27318	9	10	of	of	ADP
ajst-27318	9	11	knee	knee	NOUN
ajst-27318	9	12	cartilage	cartilage	NOUN
ajst-27318	9	13	.	.	PUNCT
ajst-27318	10	1	results	result	NOUN
ajst-27318	10	2	:	:	PUNCT
ajst-27318	10	3	compared	compare	VERB
ajst-27318	10	4	with	with	ADP
ajst-27318	10	5	the	the	DET
ajst-27318	10	6	con	con	PROPN
ajst-27318	10	7	group	group	NOUN
ajst-27318	10	8	,	,	PUNCT
ajst-27318	10	9	the	the	DET
ajst-27318	10	10	oa	oa	PROPN
ajst-27318	10	11	group	group	NOUN
ajst-27318	10	12	had	have	AUX
ajst-27318	10	13	significantly	significantly	ADV
ajst-27318	10	14	higher	high	ADJ
ajst-27318	10	15	serum	serum	NOUN
ajst-27318	10	16	levels	level	NOUN
ajst-27318	10	17	of	of	ADP
ajst-27318	10	18	tg	tg	PROPN
ajst-27318	10	19	,	,	PUNCT
ajst-27318	10	20	tc	tc	NOUN
ajst-27318	10	21	,	,	PUNCT
ajst-27318	10	22	ldl	ldl	NOUN
ajst-27318	10	23	-	-	PUNCT
ajst-27318	10	24	c	c	PROPN
ajst-27318	10	25	,	,	PUNCT
ajst-27318	10	26	mda	mda	PROPN
ajst-27318	10	27	,	,	PUNCT
ajst-27318	10	28	tnf	tnf	PROPN
ajst-27318	10	29	-	-	PUNCT
ajst-27318	10	30	α	α	PROPN
ajst-27318	10	31	and	and	CCONJ
ajst-27318	10	32	il-1β	il-1β	PROPN
ajst-27318	10	33	,	,	PUNCT
ajst-27318	10	34	and	and	CCONJ
ajst-27318	10	35	significantly	significantly	ADV
ajst-27318	10	36	lower	low	ADJ
ajst-27318	10	37	serum	serum	PROPN
ajst-27318	10	38	hdl	hdl	PROPN
ajst-27318	10	39	-	-	PUNCT
ajst-27318	10	40	c	c	NOUN
ajst-27318	10	41	level	level	NOUN
ajst-27318	10	42	and	and	CCONJ
ajst-27318	10	43	sod	sod	NOUN
ajst-27318	10	44	activity	activity	NOUN
ajst-27318	10	45	.	.	PUNCT
ajst-27318	11	1	the	the	DET
ajst-27318	11	2	results	result	NOUN
ajst-27318	11	3	of	of	ADP
ajst-27318	11	4	histopathological	histopathological	ADJ
ajst-27318	11	5	examination	examination	NOUN
ajst-27318	11	6	showed	show	VERB
ajst-27318	11	7	that	that	SCONJ
ajst-27318	11	8	there	there	PRON
ajst-27318	11	9	were	be	VERB
ajst-27318	11	10	pathological	pathological	ADJ
ajst-27318	11	11	changes	change	NOUN
ajst-27318	11	12	of	of	ADP
ajst-27318	11	13	cartilage	cartilage	NOUN
ajst-27318	11	14	tissue	tissue	NOUN
ajst-27318	11	15	damage	damage	NOUN
ajst-27318	11	16	in	in	ADP
ajst-27318	11	17	oa	oa	PROPN
ajst-27318	11	18	group	group	NOUN
ajst-27318	11	19	.	.	PUNCT
ajst-27318	12	1	compared	compare	VERB
ajst-27318	12	2	with	with	ADP
ajst-27318	12	3	the	the	DET
ajst-27318	12	4	model	model	NOUN
ajst-27318	12	5	group	group	NOUN
ajst-27318	12	6	,	,	PUNCT
ajst-27318	12	7	the	the	DET
ajst-27318	12	8	related	related	ADJ
ajst-27318	12	9	indicators	indicator	NOUN
ajst-27318	12	10	of	of	ADP
ajst-27318	12	11	the	the	DET
ajst-27318	12	12	ra	ra	PROPN
ajst-27318	12	13	group	group	NOUN
ajst-27318	12	14	were	be	AUX
ajst-27318	12	15	improved	improve	VERB
ajst-27318	12	16	to	to	ADP
ajst-27318	12	17	varying	vary	VERB
ajst-27318	12	18	degrees	degree	NOUN
ajst-27318	12	19	.	.	PUNCT
ajst-27318	13	1	conclusion	conclusion	NOUN
ajst-27318	13	2	:	:	PUNCT
ajst-27318	13	3	radix	radix	PROPN
ajst-27318	13	4	achyrandii	achyrandii	PROPN
ajst-27318	13	5	polysaccharide	polysaccharide	NOUN
ajst-27318	13	6	can	can	AUX
ajst-27318	13	7	protect	protect	VERB
ajst-27318	13	8	articular	articular	ADJ
ajst-27318	13	9	cartilage	cartilage	NOUN
ajst-27318	13	10	by	by	ADP
ajst-27318	13	11	improving	improve	VERB
ajst-27318	13	12	oa	oa	NOUN
ajst-27318	13	13	cartilage	cartilage	NOUN
ajst-27318	13	14	damage	damage	NOUN
ajst-27318	13	15	caused	cause	VERB
ajst-27318	13	16	by	by	ADP
ajst-27318	13	17	anterior	anterior	ADJ
ajst-27318	13	18	cruciate	cruciate	NOUN
ajst-27318	13	19	ligament	ligament	NOUN
ajst-27318	13	20	transection	transection	NOUN
ajst-27318	13	21	in	in	ADP
ajst-27318	13	22	obese	obese	ADJ
ajst-27318	13	23	rats	rat	NOUN
ajst-27318	13	24	,	,	PUNCT
ajst-27318	13	25	regulating	regulate	VERB
ajst-27318	13	26	blood	blood	NOUN
ajst-27318	13	27	lipid	lipid	NOUN
ajst-27318	13	28	related	relate	VERB
ajst-27318	13	29	indicators	indicator	NOUN
ajst-27318	13	30	,	,	PUNCT
ajst-27318	13	31	and	and	CCONJ
ajst-27318	13	32	inhibiting	inhibit	VERB
ajst-27318	13	33	inflammatory	inflammatory	ADJ
ajst-27318	13	34	response	response	NOUN
ajst-27318	13	35	and	and	CCONJ
ajst-27318	13	36	oxidation	oxidation	NOUN
ajst-27318	13	37	reaction	reaction	NOUN
ajst-27318	13	38	.	.	PUNCT
ajst-27318	14	1	keywords	keyword	NOUN
ajst-27318	14	2	:	:	PUNCT
ajst-27318	14	3	radix	radix	PROPN
ajst-27318	14	4	achyrandii	achyrandii	PROPN
ajst-27318	14	5	polysaccharide	polysaccharide	NOUN
ajst-27318	14	6	,	,	PUNCT
ajst-27318	14	7	high	high	ADJ
ajst-27318	14	8	fat	fat	NOUN
ajst-27318	14	9	;	;	PUNCT
ajst-27318	14	10	blood	blood	NOUN
ajst-27318	14	11	lipid	lipid	NOUN
ajst-27318	14	12	;	;	PUNCT
ajst-27318	14	13	osteoarthritis	osteoarthritis	NOUN
ajst-27318	14	14	.	.	PUNCT
ajst-27318	15	1	1	1	X
ajst-27318	15	2	.	.	X
ajst-27318	15	3	introduction	introduction	NOUN
ajst-27318	15	4	osteoarthritis	osteoarthritis	NOUN
ajst-27318	15	5	(	(	PUNCT
ajst-27318	15	6	oa	oa	X
ajst-27318	15	7	)	)	PUNCT
ajst-27318	15	8	is	be	AUX
ajst-27318	15	9	the	the	DET
ajst-27318	15	10	most	most	ADV
ajst-27318	15	11	common	common	ADJ
ajst-27318	15	12	arthritis	arthritis	NOUN
ajst-27318	15	13	disease	disease	NOUN
ajst-27318	15	14	and	and	CCONJ
ajst-27318	15	15	the	the	DET
ajst-27318	15	16	main	main	ADJ
ajst-27318	15	17	cause	cause	NOUN
ajst-27318	15	18	of	of	ADP
ajst-27318	15	19	disability	disability	NOUN
ajst-27318	15	20	and	and	CCONJ
ajst-27318	15	21	pain	pain	NOUN
ajst-27318	15	22	in	in	ADP
ajst-27318	15	23	adult	adult	NOUN
ajst-27318	15	24	patients	patient	NOUN
ajst-27318	15	25	,	,	PUNCT
ajst-27318	15	26	which	which	PRON
ajst-27318	15	27	can	can	AUX
ajst-27318	15	28	cause	cause	VERB
ajst-27318	15	29	functional	functional	ADJ
ajst-27318	15	30	impairment	impairment	NOUN
ajst-27318	15	31	and	and	CCONJ
ajst-27318	15	32	decreased	decrease	VERB
ajst-27318	15	33	quality	quality	NOUN
ajst-27318	15	34	of	of	ADP
ajst-27318	15	35	life[1	life[1	NOUN
ajst-27318	15	36	]	]	PUNCT
ajst-27318	15	37	.	.	PUNCT
ajst-27318	16	1	it	it	PRON
ajst-27318	16	2	is	be	AUX
ajst-27318	16	3	a	a	DET
ajst-27318	16	4	chronic	chronic	ADJ
ajst-27318	16	5	degenerative	degenerative	ADJ
ajst-27318	16	6	joint	joint	ADJ
ajst-27318	16	7	disease	disease	NOUN
ajst-27318	16	8	caused	cause	VERB
ajst-27318	16	9	by	by	ADP
ajst-27318	16	10	multiple	multiple	ADJ
ajst-27318	16	11	factors	factor	NOUN
ajst-27318	16	12	,	,	PUNCT
ajst-27318	16	13	which	which	PRON
ajst-27318	16	14	mainly	mainly	ADV
ajst-27318	16	15	involves	involve	VERB
ajst-27318	16	16	articular	articular	ADJ
ajst-27318	16	17	cartilage	cartilage	NOUN
ajst-27318	16	18	destruction	destruction	NOUN
ajst-27318	16	19	and	and	CCONJ
ajst-27318	16	20	simultaneously	simultaneously	ADV
ajst-27318	16	21	involves	involve	VERB
ajst-27318	16	22	periarticular	periarticular	ADJ
ajst-27318	16	23	bones	bone	NOUN
ajst-27318	16	24	,	,	PUNCT
ajst-27318	16	25	muscles	muscle	NOUN
ajst-27318	16	26	,	,	PUNCT
ajst-27318	16	27	ligaments	ligament	NOUN
ajst-27318	16	28	and	and	CCONJ
ajst-27318	16	29	synovium	synovium	NOUN
ajst-27318	16	30	.	.	PUNCT
ajst-27318	17	1	current	current	ADJ
ajst-27318	17	2	studies	study	NOUN
ajst-27318	17	3	have	have	AUX
ajst-27318	17	4	shown	show	VERB
ajst-27318	17	5	that	that	SCONJ
ajst-27318	17	6	oa	oa	ADP
ajst-27318	17	7	joint	joint	ADJ
ajst-27318	17	8	degeneration	degeneration	NOUN
ajst-27318	17	9	is	be	AUX
ajst-27318	17	10	the	the	DET
ajst-27318	17	11	result	result	NOUN
ajst-27318	17	12	of	of	ADP
ajst-27318	17	13	the	the	DET
ajst-27318	17	14	joint	joint	ADJ
ajst-27318	17	15	action	action	NOUN
ajst-27318	17	16	of	of	ADP
ajst-27318	17	17	biochemical	biochemical	ADJ
ajst-27318	17	18	factors	factor	NOUN
ajst-27318	17	19	and	and	CCONJ
ajst-27318	17	20	mechanical	mechanical	ADJ
ajst-27318	17	21	stress[2	stress[2	PROPN
ajst-27318	17	22	]	]	X
ajst-27318	17	23	.	.	PUNCT
ajst-27318	18	1	the	the	DET
ajst-27318	18	2	incidence	incidence	NOUN
ajst-27318	18	3	is	be	AUX
ajst-27318	18	4	high	high	ADJ
ajst-27318	18	5	in	in	ADP
ajst-27318	18	6	middle	middle	NOUN
ajst-27318	18	7	-	-	PUNCT
ajst-27318	18	8	aged	aged	ADJ
ajst-27318	18	9	and	and	CCONJ
ajst-27318	18	10	elderly	elderly	ADJ
ajst-27318	18	11	people	people	NOUN
ajst-27318	18	12	,	,	PUNCT
ajst-27318	18	13	especially	especially	ADV
ajst-27318	18	14	those	those	PRON
ajst-27318	18	15	with	with	ADP
ajst-27318	18	16	obesity	obesity	NOUN
ajst-27318	18	17	.	.	PUNCT
ajst-27318	19	1	in	in	ADP
ajst-27318	19	2	the	the	DET
ajst-27318	19	3	united	united	PROPN
ajst-27318	19	4	states	states	PROPN
ajst-27318	19	5	,	,	PUNCT
ajst-27318	19	6	the	the	DET
ajst-27318	19	7	incidence	incidence	NOUN
ajst-27318	19	8	of	of	ADP
ajst-27318	19	9	knee	knee	NOUN
ajst-27318	19	10	osteoarthritis	osteoarthritis	NOUN
ajst-27318	19	11	(	(	PUNCT
ajst-27318	19	12	koa	koa	PROPN
ajst-27318	19	13	)	)	PUNCT
ajst-27318	19	14	among	among	ADP
ajst-27318	19	15	people	people	NOUN
ajst-27318	19	16	aged	age	VERB
ajst-27318	19	17	60	60	NUM
ajst-27318	19	18	years	year	NOUN
ajst-27318	19	19	and	and	CCONJ
ajst-27318	19	20	over	over	ADV
ajst-27318	19	21	is	be	AUX
ajst-27318	19	22	about	about	ADV
ajst-27318	19	23	10	10	NUM
ajst-27318	19	24	%	%	NOUN
ajst-27318	19	25	in	in	ADP
ajst-27318	19	26	men	man	NOUN
ajst-27318	19	27	and	and	CCONJ
ajst-27318	19	28	13	13	NUM
ajst-27318	19	29	%	%	NOUN
ajst-27318	19	30	in	in	ADP
ajst-27318	19	31	women	woman	NOUN
ajst-27318	19	32	,	,	PUNCT
ajst-27318	19	33	and	and	CCONJ
ajst-27318	19	34	it	it	PRON
ajst-27318	19	35	continues	continue	VERB
ajst-27318	19	36	to	to	PART
ajst-27318	19	37	increase	increase	VERB
ajst-27318	19	38	with	with	ADP
ajst-27318	19	39	the	the	DET
ajst-27318	19	40	increase	increase	NOUN
ajst-27318	19	41	of	of	ADP
ajst-27318	19	42	age	age	NOUN
ajst-27318	19	43	and	and	CCONJ
ajst-27318	19	44	the	the	DET
ajst-27318	19	45	prevalence	prevalence	NOUN
ajst-27318	19	46	of	of	ADP
ajst-27318	19	47	obesity[3	obesity[3	NOUN
ajst-27318	19	48	]	]	PUNCT
ajst-27318	19	49	.	.	PUNCT
ajst-27318	20	1	it	it	PRON
ajst-27318	20	2	is	be	AUX
ajst-27318	20	3	expected	expect	VERB
ajst-27318	20	4	that	that	SCONJ
ajst-27318	20	5	by	by	ADP
ajst-27318	20	6	2020	2020	NUM
ajst-27318	20	7	,	,	PUNCT
ajst-27318	20	8	more	more	ADJ
ajst-27318	20	9	than	than	ADP
ajst-27318	20	10	50	50	NUM
ajst-27318	20	11	million	million	NUM
ajst-27318	20	12	people	people	NOUN
ajst-27318	20	13	in	in	ADP
ajst-27318	20	14	the	the	DET
ajst-27318	20	15	united	united	PROPN
ajst-27318	20	16	states	states	PROPN
ajst-27318	20	17	will	will	AUX
ajst-27318	20	18	suffer	suffer	VERB
ajst-27318	20	19	from	from	ADP
ajst-27318	20	20	this	this	DET
ajst-27318	20	21	disease	disease	NOUN
ajst-27318	20	22	,	,	PUNCT
ajst-27318	20	23	and	and	CCONJ
ajst-27318	20	24	it	it	PRON
ajst-27318	20	25	will	will	AUX
ajst-27318	20	26	become	become	VERB
ajst-27318	20	27	an	an	DET
ajst-27318	20	28	important	important	ADJ
ajst-27318	20	29	factor	factor	NOUN
ajst-27318	20	30	causing	cause	VERB
ajst-27318	20	31	disability	disability	NOUN
ajst-27318	20	32	and	and	CCONJ
ajst-27318	20	33	activity	activity	NOUN
ajst-27318	20	34	limitation	limitation	NOUN
ajst-27318	20	35	for	for	ADP
ajst-27318	20	36	people	people	NOUN
ajst-27318	20	37	over	over	ADP
ajst-27318	20	38	the	the	DET
ajst-27318	20	39	age	age	NOUN
ajst-27318	20	40	of	of	ADP
ajst-27318	20	41	40[4	40[4	NUM
ajst-27318	20	42	]	]	PUNCT
ajst-27318	20	43	.	.	PUNCT
ajst-27318	21	1	from	from	ADP
ajst-27318	21	2	the	the	DET
ajst-27318	21	3	perspective	perspective	NOUN
ajst-27318	21	4	of	of	ADP
ajst-27318	21	5	pathogenic	pathogenic	ADJ
ajst-27318	21	6	characteristics	characteristic	NOUN
ajst-27318	21	7	,	,	PUNCT
ajst-27318	21	8	oa	oa	PROPN
ajst-27318	21	9	is	be	AUX
ajst-27318	21	10	most	most	ADV
ajst-27318	21	11	common	common	ADJ
ajst-27318	21	12	in	in	ADP
ajst-27318	21	13	weight	weight	NOUN
ajst-27318	21	14	-	-	PUNCT
ajst-27318	21	15	bearing	bear	VERB
ajst-27318	21	16	joints	joint	NOUN
ajst-27318	21	17	such	such	ADJ
ajst-27318	21	18	as	as	ADP
ajst-27318	21	19	hip	hip	NOUN
ajst-27318	21	20	and	and	CCONJ
ajst-27318	21	21	knee	knee	NOUN
ajst-27318	21	22	,	,	PUNCT
ajst-27318	21	23	and	and	CCONJ
ajst-27318	21	24	is	be	AUX
ajst-27318	21	25	mainly	mainly	ADV
ajst-27318	21	26	characterized	characterize	VERB
ajst-27318	21	27	by	by	ADP
ajst-27318	21	28	joint	joint	ADJ
ajst-27318	21	29	pain	pain	NOUN
ajst-27318	21	30	,	,	PUNCT
ajst-27318	21	31	limited	limited	ADJ
ajst-27318	21	32	activity	activity	NOUN
ajst-27318	21	33	and	and	CCONJ
ajst-27318	21	34	degeneration	degeneration	NOUN
ajst-27318	21	35	of	of	ADP
ajst-27318	21	36	articular	articular	NOUN
ajst-27318	21	37	cartilage[5	cartilage[5	PROPN
ajst-27318	21	38	]	]	PUNCT
ajst-27318	21	39	.	.	PUNCT
ajst-27318	22	1	in	in	ADP
ajst-27318	22	2	addition	addition	NOUN
ajst-27318	22	3	to	to	ADP
ajst-27318	22	4	articular	articular	ADJ
ajst-27318	22	5	cartilage	cartilage	NOUN
ajst-27318	22	6	,	,	PUNCT
ajst-27318	22	7	the	the	DET
ajst-27318	22	8	affected	affected	ADJ
ajst-27318	22	9	parts	part	NOUN
ajst-27318	22	10	also	also	ADV
ajst-27318	22	11	include	include	VERB
ajst-27318	22	12	synovial	synovial	ADJ
ajst-27318	22	13	membrane	membrane	NOUN
ajst-27318	22	14	,	,	PUNCT
ajst-27318	22	15	ligament	ligament	NOUN
ajst-27318	22	16	,	,	PUNCT
ajst-27318	22	17	meniscus	meniscus	NOUN
ajst-27318	22	18	and	and	CCONJ
ajst-27318	22	19	periarticular	periarticular	ADJ
ajst-27318	22	20	muscles[6	muscles[6	NUM
ajst-27318	22	21	]	]	PUNCT
ajst-27318	22	22	.	.	PUNCT
ajst-27318	23	1	at	at	ADP
ajst-27318	23	2	present	present	ADJ
ajst-27318	23	3	,	,	PUNCT
ajst-27318	23	4	there	there	PRON
ajst-27318	23	5	is	be	VERB
ajst-27318	23	6	no	no	DET
ajst-27318	23	7	unified	unified	ADJ
ajst-27318	23	8	understanding	understanding	NOUN
ajst-27318	23	9	of	of	ADP
ajst-27318	23	10	the	the	DET
ajst-27318	23	11	pathogenesis	pathogenesis	NOUN
ajst-27318	23	12	of	of	ADP
ajst-27318	23	13	oa	oa	NOUN
ajst-27318	23	14	,	,	PUNCT
ajst-27318	23	15	which	which	PRON
ajst-27318	23	16	is	be	AUX
ajst-27318	23	17	greatly	greatly	ADV
ajst-27318	23	18	affected	affect	VERB
ajst-27318	23	19	by	by	ADP
ajst-27318	23	20	"	"	PUNCT
ajst-27318	23	21	modern	modern	ADJ
ajst-27318	23	22	environmental	environmental	ADJ
ajst-27318	23	23	"	"	PUNCT
ajst-27318	23	24	factors	factor	NOUN
ajst-27318	23	25	such	such	ADJ
ajst-27318	23	26	as	as	ADP
ajst-27318	23	27	obesity	obesity	NOUN
ajst-27318	23	28	,	,	PUNCT
ajst-27318	23	29	metabolic	metabolic	NOUN
ajst-27318	23	30	syndrome	syndrome	NOUN
ajst-27318	23	31	,	,	PUNCT
ajst-27318	23	32	diet	diet	NOUN
ajst-27318	23	33	change	change	NOUN
ajst-27318	23	34	,	,	PUNCT
ajst-27318	23	35	sedentary	sedentary	ADJ
ajst-27318	23	36	lifestyle	lifestyle	NOUN
ajst-27318	23	37	or	or	CCONJ
ajst-27318	23	38	improper	improper	ADJ
ajst-27318	23	39	exercise[7	exercise[7	NOUN
ajst-27318	23	40	]	]	PUNCT
ajst-27318	23	41	.	.	PUNCT
ajst-27318	24	1	the	the	DET
ajst-27318	24	2	traditional	traditional	ADJ
ajst-27318	24	3	view	view	NOUN
ajst-27318	24	4	is	be	AUX
ajst-27318	24	5	that	that	SCONJ
ajst-27318	24	6	oa	oa	PROPN
ajst-27318	24	7	is	be	AUX
ajst-27318	24	8	only	only	ADV
ajst-27318	24	9	a	a	DET
ajst-27318	24	10	joint	joint	ADJ
ajst-27318	24	11	disease	disease	NOUN
ajst-27318	24	12	caused	cause	VERB
ajst-27318	24	13	by	by	ADP
ajst-27318	24	14	mechanical	mechanical	ADJ
ajst-27318	24	15	stress	stress	NOUN
ajst-27318	24	16	changes	change	NOUN
ajst-27318	24	17	caused	cause	VERB
ajst-27318	24	18	by	by	ADP
ajst-27318	24	19	aging	age	VERB
ajst-27318	24	20	and	and	CCONJ
ajst-27318	24	21	sports	sport	NOUN
ajst-27318	24	22	trauma	trauma	NOUN
ajst-27318	24	23	,	,	PUNCT
ajst-27318	24	24	but	but	CCONJ
ajst-27318	24	25	a	a	DET
ajst-27318	24	26	large	large	ADJ
ajst-27318	24	27	number	number	NOUN
ajst-27318	24	28	of	of	ADP
ajst-27318	24	29	epidemiological	epidemiological	ADJ
ajst-27318	24	30	and	and	CCONJ
ajst-27318	24	31	biological	biological	ADJ
ajst-27318	24	32	data	datum	NOUN
ajst-27318	24	33	show	show	NOUN
ajst-27318	24	34	that[8	that[8	NOUN
ajst-27318	24	35	]	]	PUNCT
ajst-27318	24	36	oa	oa	PRON
ajst-27318	24	37	is	be	AUX
ajst-27318	24	38	closely	closely	ADV
ajst-27318	24	39	related	relate	VERB
ajst-27318	24	40	to	to	ADP
ajst-27318	24	41	metabolic	metabolic	NOUN
ajst-27318	24	42	and	and	CCONJ
ajst-27318	24	43	inflammatory	inflammatory	ADJ
ajst-27318	24	44	factors[9	factors[9	NOUN
ajst-27318	24	45	]	]	PUNCT
ajst-27318	24	46	.	.	PUNCT
ajst-27318	25	1	from	from	ADP
ajst-27318	25	2	the	the	DET
ajst-27318	25	3	related	related	ADJ
ajst-27318	25	4	studies	study	NOUN
ajst-27318	25	5	of	of	ADP
ajst-27318	25	6	obesity	obesity	NOUN
ajst-27318	25	7	and	and	CCONJ
ajst-27318	25	8	oa	oa	INTJ
ajst-27318	25	9	,	,	PUNCT
ajst-27318	25	10	it	it	PRON
ajst-27318	25	11	can	can	AUX
ajst-27318	25	12	be	be	AUX
ajst-27318	25	13	seen	see	VERB
ajst-27318	25	14	that	that	SCONJ
ajst-27318	25	15	both	both	CCONJ
ajst-27318	25	16	the	the	DET
ajst-27318	25	17	external	external	ADJ
ajst-27318	25	18	mechanical	mechanical	ADJ
ajst-27318	25	19	stress	stress	NOUN
ajst-27318	25	20	factors	factor	NOUN
ajst-27318	25	21	of	of	ADP
ajst-27318	25	22	obesity	obesity	NOUN
ajst-27318	25	23	and	and	CCONJ
ajst-27318	25	24	the	the	DET
ajst-27318	25	25	intrinsic	intrinsic	ADJ
ajst-27318	25	26	lipid	lipid	NOUN
ajst-27318	25	27	metabolism	metabolism	NOUN
ajst-27318	25	28	and	and	CCONJ
ajst-27318	25	29	other	other	ADJ
ajst-27318	25	30	factors	factor	NOUN
ajst-27318	25	31	have	have	VERB
ajst-27318	25	32	a	a	DET
ajst-27318	25	33	certain	certain	ADJ
ajst-27318	25	34	correlation	correlation	NOUN
ajst-27318	25	35	with	with	ADP
ajst-27318	25	36	the	the	DET
ajst-27318	25	37	pathological	pathological	ADJ
ajst-27318	25	38	changes	change	NOUN
ajst-27318	25	39	of	of	ADP
ajst-27318	25	40	oa	oa	PROPN
ajst-27318	25	41	synovial	synovial	ADJ
ajst-27318	25	42	membrane	membrane	NOUN
ajst-27318	25	43	and	and	CCONJ
ajst-27318	25	44	cartilage	cartilage	NOUN
ajst-27318	25	45	,	,	PUNCT
ajst-27318	25	46	inflammatory	inflammatory	ADJ
ajst-27318	25	47	response	response	NOUN
ajst-27318	25	48	and	and	CCONJ
ajst-27318	25	49	pain[10	pain[10	NOUN
ajst-27318	25	50	]	]	PUNCT
ajst-27318	25	51	.	.	PUNCT
ajst-27318	26	1	chinese	chinese	ADJ
ajst-27318	26	2	herbal	herbal	ADJ
ajst-27318	26	3	medicine	medicine	NOUN
ajst-27318	26	4	has	have	VERB
ajst-27318	26	5	definite	definite	ADJ
ajst-27318	26	6	curative	curative	ADJ
ajst-27318	26	7	effect	effect	NOUN
ajst-27318	26	8	,	,	PUNCT
ajst-27318	26	9	few	few	ADJ
ajst-27318	26	10	side	side	NOUN
ajst-27318	26	11	effects	effect	NOUN
ajst-27318	26	12	and	and	CCONJ
ajst-27318	26	13	overall	overall	ADJ
ajst-27318	26	14	regulation	regulation	NOUN
ajst-27318	26	15	effect	effect	NOUN
ajst-27318	26	16	of	of	ADP
ajst-27318	26	17	multiple	multiple	ADJ
ajst-27318	26	18	targets	target	NOUN
ajst-27318	26	19	in	in	ADP
ajst-27318	26	20	the	the	DET
ajst-27318	26	21	prevention	prevention	NOUN
ajst-27318	26	22	and	and	CCONJ
ajst-27318	26	23	treatment	treatment	NOUN
ajst-27318	26	24	of	of	ADP
ajst-27318	26	25	oa[11	oa[11	NUM
ajst-27318	26	26	]	]	PUNCT
ajst-27318	26	27	.	.	PUNCT
ajst-27318	27	1	studies	study	NOUN
ajst-27318	27	2	have	have	AUX
ajst-27318	27	3	shown	show	VERB
ajst-27318	27	4	that	that	DET
ajst-27318	27	5	polysaccharide	polysaccharide	NOUN
ajst-27318	27	6	from	from	ADP
ajst-27318	27	7	radix	radix	PROPN
ajst-27318	27	8	achyrandii	achyrandii	NOUN
ajst-27318	27	9	can	can	AUX
ajst-27318	27	10	not	not	PART
ajst-27318	27	11	only	only	ADV
ajst-27318	27	12	enhance	enhance	VERB
ajst-27318	27	13	natural	natural	ADJ
ajst-27318	27	14	killer	killer	NOUN
ajst-27318	27	15	cell	cell	NOUN
ajst-27318	27	16	-	-	PUNCT
ajst-27318	27	17	mediated	mediate	VERB
ajst-27318	27	18	cytotoxicity	cytotoxicity	NOUN
ajst-27318	27	19	and	and	CCONJ
ajst-27318	27	20	promote	promote	VERB
ajst-27318	27	21	the	the	DET
ajst-27318	27	22	proliferation	proliferation	NOUN
ajst-27318	27	23	of	of	ADP
ajst-27318	27	24	spleen	spleen	NOUN
ajst-27318	27	25	cells	cell	NOUN
ajst-27318	27	26	,	,	PUNCT
ajst-27318	27	27	but	but	CCONJ
ajst-27318	27	28	also	also	ADV
ajst-27318	27	29	increase	increase	VERB
ajst-27318	27	30	the	the	DET
ajst-27318	27	31	phagocytic	phagocytic	ADJ
ajst-27318	27	32	function	function	NOUN
ajst-27318	27	33	of	of	ADP
ajst-27318	27	34	macrophages	macrophage	NOUN
ajst-27318	27	35	and	and	CCONJ
ajst-27318	27	36	the	the	DET
ajst-27318	27	37	production	production	NOUN
ajst-27318	27	38	of	of	ADP
ajst-27318	27	39	nitric	nitric	ADJ
ajst-27318	27	40	oxide	oxide	NOUN
ajst-27318	27	41	.	.	PUNCT
ajst-27318	28	1	radix	radix	PROPN
ajst-27318	28	2	achyrandii	achyrandii	PROPN
ajst-27318	28	3	polysaccharide	polysaccharide	NOUN
ajst-27318	28	4	can	can	AUX
ajst-27318	28	5	reduce	reduce	VERB
ajst-27318	28	6	inflammatory	inflammatory	ADJ
ajst-27318	28	7	response	response	NOUN
ajst-27318	28	8	by	by	ADP
ajst-27318	28	9	inhibiting	inhibit	VERB
ajst-27318	28	10	the	the	DET
ajst-27318	28	11	secretion	secretion	NOUN
ajst-27318	28	12	of	of	ADP
ajst-27318	28	13	inflammatory	inflammatory	ADJ
ajst-27318	28	14	factors	factor	NOUN
ajst-27318	28	15	,	,	PUNCT
ajst-27318	28	16	and	and	CCONJ
ajst-27318	28	17	can	can	AUX
ajst-27318	28	18	play	play	VERB
ajst-27318	28	19	an	an	DET
ajst-27318	28	20	important	important	ADJ
ajst-27318	28	21	role	role	NOUN
ajst-27318	28	22	in	in	ADP
ajst-27318	28	23	the	the	DET
ajst-27318	28	24	body	body	NOUN
ajst-27318	28	25	's	's	PART
ajst-27318	28	26	antioxidant[12	antioxidant[12	NOUN
ajst-27318	28	27	]	]	PUNCT
ajst-27318	28	28	.	.	PUNCT
ajst-27318	29	1	however	however	ADV
ajst-27318	29	2	,	,	PUNCT
ajst-27318	29	3	whether	whether	SCONJ
ajst-27318	29	4	radix	radix	NOUN
ajst-27318	29	5	achyrandii	achyrandii	PROPN
ajst-27318	29	6	polysaccharide	polysaccharide	NOUN
ajst-27318	29	7	exerts	exert	VERB
ajst-27318	29	8	its	its	PRON
ajst-27318	29	9	protective	protective	ADJ
ajst-27318	29	10	effect	effect	NOUN
ajst-27318	29	11	on	on	ADP
ajst-27318	29	12	oa	oa	NOUN
ajst-27318	29	13	through	through	ADP
ajst-27318	29	14	oxidative	oxidative	ADJ
ajst-27318	29	15	stress	stress	NOUN
ajst-27318	29	16	is	be	AUX
ajst-27318	29	17	poorly	poorly	ADV
ajst-27318	29	18	studied	study	VERB
ajst-27318	29	19	.	.	PUNCT
ajst-27318	30	1	therefore	therefore	ADV
ajst-27318	30	2	,	,	PUNCT
ajst-27318	30	3	in	in	ADP
ajst-27318	30	4	this	this	DET
ajst-27318	30	5	study	study	NOUN
ajst-27318	30	6	,	,	PUNCT
ajst-27318	30	7	knee	knee	NOUN
ajst-27318	30	8	osteoarthritis	osteoarthritis	NOUN
ajst-27318	30	9	was	be	AUX
ajst-27318	30	10	induced	induce	VERB
ajst-27318	30	11	by	by	ADP
ajst-27318	30	12	high	high	ADJ
ajst-27318	30	13	-	-	PUNCT
ajst-27318	30	14	fat	fat	NOUN
ajst-27318	30	15	diet	diet	NOUN
ajst-27318	30	16	in	in	ADP
ajst-27318	30	17	c57bl/6	c57bl/6	NOUN
ajst-27318	30	18	male	male	ADJ
ajst-27318	30	19	mice	mouse	NOUN
ajst-27318	30	20	,	,	PUNCT
ajst-27318	30	21	so	so	SCONJ
ajst-27318	30	22	as	as	SCONJ
ajst-27318	30	23	to	to	PART
ajst-27318	30	24	establish	establish	VERB
ajst-27318	30	25	an	an	DET
ajst-27318	30	26	osteoarthritis	osteoarthritis	NOUN
ajst-27318	30	27	model	model	NOUN
ajst-27318	30	28	,	,	PUNCT
ajst-27318	30	29	observe	observe	VERB
ajst-27318	30	30	the	the	DET
ajst-27318	30	31	morphological	morphological	ADJ
ajst-27318	30	32	changes	change	NOUN
ajst-27318	30	33	of	of	ADP
ajst-27318	30	34	knee	knee	NOUN
ajst-27318	30	35	cartilage	cartilage	NOUN
ajst-27318	30	36	and	and	CCONJ
ajst-27318	30	37	explore	explore	VERB
ajst-27318	30	38	the	the	DET
ajst-27318	30	39	protective	protective	ADJ
ajst-27318	30	40	effect	effect	NOUN
ajst-27318	30	41	of	of	ADP
ajst-27318	30	42	independent	independent	ADJ
ajst-27318	30	43	radix	radix	PROPN
ajst-27318	30	44	achyrandii	achyrandii	NOUN
ajst-27318	30	45	polysaccharide	polysaccharide	ADV
ajst-27318	30	46	on	on	ADP
ajst-27318	30	47	knee	knee	NOUN
ajst-27318	30	48	osteoarthritis	osteoarthritis	NOUN
ajst-27318	30	49	cartilage	cartilage	NOUN
ajst-27318	30	50	,	,	PUNCT
ajst-27318	30	51	in	in	ADP
ajst-27318	30	52	order	order	NOUN
ajst-27318	30	53	to	to	PART
ajst-27318	30	54	provide	provide	VERB
ajst-27318	30	55	effective	effective	ADJ
ajst-27318	30	56	experimental	experimental	ADJ
ajst-27318	30	57	evidence	evidence	NOUN
ajst-27318	30	58	for	for	ADP
ajst-27318	30	59	clinical	clinical	ADJ
ajst-27318	30	60	treatment	treatment	NOUN
ajst-27318	30	61	75	75	NUM
ajst-27318	30	62	of	of	ADP
ajst-27318	30	63	metabolic	metabolic	ADJ
ajst-27318	30	64	knee	knee	NOUN
ajst-27318	30	65	osteoarthritis	osteoarthritis	NOUN
ajst-27318	30	66	.	.	PUNCT
ajst-27318	31	1	2	2	X
ajst-27318	31	2	.	.	X
ajst-27318	31	3	materials	material	NOUN
ajst-27318	31	4	and	and	CCONJ
ajst-27318	31	5	methods	method	NOUN
ajst-27318	31	6	2.1	2.1	NUM
ajst-27318	31	7	.	.	PUNCT
ajst-27318	32	1	reagents	reagent	NOUN
ajst-27318	32	2	radix	radix	NOUN
ajst-27318	32	3	achyrandii	achyrandii	PROPN
ajst-27318	32	4	polysaccharide	polysaccharide	NOUN
ajst-27318	32	5	was	be	AUX
ajst-27318	32	6	purchased	purchase	VERB
ajst-27318	32	7	from	from	ADP
ajst-27318	32	8	shanghai	shanghai	PROPN
ajst-27318	32	9	puzhen	puzhen	PROPN
ajst-27318	32	10	biotechnology	biotechnology	PROPN
ajst-27318	32	11	co.	co.	PROPN
ajst-27318	32	12	,	,	PUNCT
ajst-27318	32	13	ltd	ltd	PROPN
ajst-27318	32	14	.	.	PROPN
ajst-27318	32	15	serum	serum	PROPN
ajst-27318	33	1	triglyceride	triglyceride	ADV
ajst-27318	33	2	(	(	PUNCT
ajst-27318	33	3	tg	tg	PROPN
ajst-27318	33	4	)	)	PUNCT
ajst-27318	33	5	,	,	PUNCT
ajst-27318	33	6	total	total	ADJ
ajst-27318	33	7	cholesterol	cholesterol	NOUN
ajst-27318	33	8	(	(	PUNCT
ajst-27318	33	9	tc	tc	NOUN
ajst-27318	33	10	)	)	PUNCT
ajst-27318	33	11	,	,	PUNCT
ajst-27318	33	12	high	high	ADJ
ajst-27318	33	13	-	-	PUNCT
ajst-27318	33	14	density	density	NOUN
ajst-27318	33	15	lipoprotein	lipoprotein	ADJ
ajst-27318	33	16	cholesterol	cholesterol	NOUN
ajst-27318	33	17	(	(	PUNCT
ajst-27318	33	18	hdl	hdl	NOUN
ajst-27318	33	19	-	-	PUNCT
ajst-27318	33	20	c	c	NOUN
ajst-27318	33	21	)	)	PUNCT
ajst-27318	33	22	,	,	PUNCT
ajst-27318	33	23	and	and	CCONJ
ajst-27318	33	24	low	low	ADJ
ajst-27318	33	25	-	-	PUNCT
ajst-27318	33	26	density	density	NOUN
ajst-27318	33	27	lipoprotein	lipoprotein	ADJ
ajst-27318	33	28	cholesterol	cholesterol	NOUN
ajst-27318	33	29	(	(	PUNCT
ajst-27318	33	30	ldl	ldl	NOUN
ajst-27318	33	31	-	-	PUNCT
ajst-27318	33	32	c	c	NOUN
ajst-27318	33	33	)	)	PUNCT
ajst-27318	33	34	biochemical	biochemical	ADJ
ajst-27318	33	35	kits	kit	NOUN
ajst-27318	33	36	were	be	AUX
ajst-27318	33	37	purchased	purchase	VERB
ajst-27318	33	38	from	from	ADP
ajst-27318	33	39	nanjing	nanjing	PROPN
ajst-27318	33	40	jiancheng	jiancheng	PROPN
ajst-27318	33	41	bioengineering	bioengineering	PROPN
ajst-27318	33	42	institute	institute	PROPN
ajst-27318	33	43	.	.	PUNCT
ajst-27318	34	1	serum	serum	PROPN
ajst-27318	34	2	superoxide	superoxide	NOUN
ajst-27318	34	3	dismutase	dismutase	NOUN
ajst-27318	34	4	(	(	PUNCT
ajst-27318	34	5	sod	sod	NOUN
ajst-27318	34	6	)	)	PUNCT
ajst-27318	34	7	activity	activity	NOUN
ajst-27318	34	8	,	,	PUNCT
ajst-27318	34	9	malondialdehyde	malondialdehyde	NOUN
ajst-27318	34	10	(	(	PUNCT
ajst-27318	34	11	mda	mda	PROPN
ajst-27318	34	12	)	)	PUNCT
ajst-27318	34	13	concentration	concentration	NOUN
ajst-27318	34	14	and	and	CCONJ
ajst-27318	34	15	interleukin-1β	interleukin-1β	NOUN
ajst-27318	34	16	(	(	PUNCT
ajst-27318	34	17	il-1β	il-1β	PROPN
ajst-27318	34	18	)	)	PUNCT
ajst-27318	34	19	and	and	CCONJ
ajst-27318	34	20	tumor	tumor	NOUN
ajst-27318	34	21	necrosis	necrosis	NOUN
ajst-27318	34	22	factor	factor	NOUN
ajst-27318	34	23	-	-	PUNCT
ajst-27318	34	24	α	α	X
ajst-27318	34	25	(	(	PUNCT
ajst-27318	34	26	tnf	tnf	PROPN
ajst-27318	34	27	-	-	PUNCT
ajst-27318	34	28	α	α	NOUN
ajst-27318	34	29	)	)	PUNCT
ajst-27318	34	30	enzyme	enzyme	NOUN
ajst-27318	34	31	-	-	PUNCT
ajst-27318	34	32	linked	link	VERB
ajst-27318	34	33	immunosorbent	immunosorbent	NOUN
ajst-27318	34	34	assay	assay	PROPN
ajst-27318	34	35	(	(	PUNCT
ajst-27318	34	36	elisa	elisa	NOUN
ajst-27318	34	37	)	)	PUNCT
ajst-27318	34	38	kits	kit	NOUN
ajst-27318	34	39	were	be	AUX
ajst-27318	34	40	purchased	purchase	VERB
ajst-27318	34	41	from	from	ADP
ajst-27318	34	42	shanghai	shanghai	PROPN
ajst-27318	34	43	bangyi	bangyi	PROPN
ajst-27318	34	44	biotechnology	biotechnology	PROPN
ajst-27318	34	45	co.	co.	PROPN
ajst-27318	34	46	,	,	PUNCT
ajst-27318	34	47	ltd	ltd	PROPN
ajst-27318	34	48	.	.	PROPN
ajst-27318	34	49	hematoxylin	hematoxylin	NOUN
ajst-27318	34	50	-	-	PUNCT
ajst-27318	34	51	eosin	eosin	NOUN
ajst-27318	34	52	staining	stain	VERB
ajst-27318	34	53	(	(	PUNCT
ajst-27318	34	54	he	he	PRON
ajst-27318	34	55	)	)	PUNCT
ajst-27318	34	56	staining	stain	VERB
ajst-27318	34	57	kit	kit	NOUN
ajst-27318	34	58	was	be	AUX
ajst-27318	34	59	purchased	purchase	VERB
ajst-27318	34	60	from	from	ADP
ajst-27318	34	61	shanghai	shanghai	PROPN
ajst-27318	34	62	biyuntian	biyuntian	PROPN
ajst-27318	34	63	biotechnology	biotechnology	PROPN
ajst-27318	34	64	co.	co.	PROPN
ajst-27318	34	65	,	,	PUNCT
ajst-27318	34	66	ltd	ltd	PROPN
ajst-27318	34	67	.	.	PROPN
ajst-27318	34	68	ripa	ripa	ADJ
ajst-27318	34	69	tissue	tissue	NOUN
ajst-27318	34	70	cell	cell	NOUN
ajst-27318	34	71	rapid	rapid	ADJ
ajst-27318	34	72	lysate	lysate	NOUN
ajst-27318	34	73	was	be	AUX
ajst-27318	34	74	purchased	purchase	VERB
ajst-27318	34	75	from	from	ADP
ajst-27318	34	76	beijing	beijing	PROPN
ajst-27318	34	77	solaibao	solaibao	PROPN
ajst-27318	34	78	technology	technology	PROPN
ajst-27318	34	79	co.	co.	PROPN
ajst-27318	34	80	,	,	PUNCT
ajst-27318	34	81	ltd	ltd	PROPN
ajst-27318	34	82	.	.	PROPN
ajst-27318	35	1	(	(	PUNCT
ajst-27318	35	2	item	item	NOUN
ajst-27318	35	3	number	number	NOUN
ajst-27318	35	4	:	:	PUNCT
ajst-27318	35	5	t8220	t8220	NOUN
ajst-27318	35	6	)	)	PUNCT
ajst-27318	35	7	.	.	PUNCT
ajst-27318	36	1	nc	nc	PROPN
ajst-27318	36	2	membranes	membrane	NOUN
ajst-27318	36	3	were	be	AUX
ajst-27318	36	4	purchased	purchase	VERB
ajst-27318	36	5	from	from	ADP
ajst-27318	36	6	merck	merck	PROPN
ajst-27318	36	7	millipore	millipore	PROPN
ajst-27318	36	8	(	(	PUNCT
ajst-27318	36	9	hatf00010	hatf00010	PROPN
ajst-27318	36	10	)	)	PUNCT
ajst-27318	36	11	;	;	PUNCT
ajst-27318	36	12	luminescent	luminescent	NOUN
ajst-27318	36	13	solution	solution	NOUN
ajst-27318	36	14	was	be	AUX
ajst-27318	36	15	purchased	purchase	VERB
ajst-27318	36	16	from	from	ADP
ajst-27318	36	17	millipore	millipore	PROPN
ajst-27318	36	18	(	(	PUNCT
ajst-27318	36	19	product	product	NOUN
ajst-27318	36	20	number	number	NOUN
ajst-27318	36	21	:	:	PUNCT
ajst-27318	36	22	wbkls0100	wbkls0100	PROPN
ajst-27318	36	23	)	)	PUNCT
ajst-27318	36	24	;	;	PUNCT
ajst-27318	36	25	broad	broad	ADJ
ajst-27318	36	26	-	-	PUNCT
ajst-27318	36	27	spectrum	spectrum	NOUN
ajst-27318	36	28	secondary	secondary	ADJ
ajst-27318	36	29	antibody	antibody	NOUN
ajst-27318	36	30	was	be	AUX
ajst-27318	36	31	purchased	purchase	VERB
ajst-27318	36	32	from	from	ADP
ajst-27318	36	33	shanghai	shanghai	PROPN
ajst-27318	36	34	changdao	changdao	PROPN
ajst-27318	36	35	biotechnology	biotechnology	PROPN
ajst-27318	36	36	co.	co.	PROPN
ajst-27318	36	37	,	,	PUNCT
ajst-27318	36	38	ltd	ltd	PROPN
ajst-27318	36	39	.	.	PROPN
ajst-27318	37	1	(	(	PUNCT
ajst-27318	37	2	item	item	NOUN
ajst-27318	37	3	number	number	NOUN
ajst-27318	37	4	:	:	PUNCT
ajst-27318	37	5	d-3004	d-3004	PROPN
ajst-27318	37	6	)	)	PUNCT
ajst-27318	37	7	.	.	PUNCT
ajst-27318	38	1	mpp-3	mpp-3	X
ajst-27318	38	2	antibody	antibody	NOUN
ajst-27318	38	3	(	(	PUNCT
ajst-27318	38	4	product	product	NOUN
ajst-27318	38	5	number	number	NOUN
ajst-27318	38	6	:	:	PUNCT
ajst-27318	38	7	ab52915	ab52915	NOUN
ajst-27318	38	8	)	)	PUNCT
ajst-27318	39	1	,	,	PUNCT
ajst-27318	39	2	timp-1	timp-1	NUM
ajst-27318	39	3	antibody	antibody	NOUN
ajst-27318	39	4	(	(	PUNCT
ajst-27318	39	5	product	product	NOUN
ajst-27318	39	6	number	number	NOUN
ajst-27318	39	7	:	:	PUNCT
ajst-27318	39	8	ab221435	ab221435	PROPN
ajst-27318	39	9	)	)	PUNCT
ajst-27318	39	10	,	,	PUNCT
ajst-27318	39	11	and	and	CCONJ
ajst-27318	39	12	gapdh	gapdh	NOUN
ajst-27318	39	13	antibody	antibody	NOUN
ajst-27318	39	14	(	(	PUNCT
ajst-27318	39	15	product	product	NOUN
ajst-27318	39	16	number	number	NOUN
ajst-27318	39	17	:	:	PUNCT
ajst-27318	39	18	ab8245	ab8245	PROPN
ajst-27318	39	19	)	)	PUNCT
ajst-27318	39	20	were	be	AUX
ajst-27318	39	21	purchased	purchase	VERB
ajst-27318	39	22	from	from	ADP
ajst-27318	39	23	abcam	abcam	NOUN
ajst-27318	39	24	.	.	PUNCT
ajst-27318	40	1	2.2	2.2	NUM
ajst-27318	40	2	.	.	PUNCT
ajst-27318	41	1	oa	oa	NOUN
ajst-27318	41	2	model	model	NOUN
ajst-27318	41	3	and	and	CCONJ
ajst-27318	41	4	group	group	PROPN
ajst-27318	41	5	administration	administration	NOUN
ajst-27318	41	6	thirty	thirty	NUM
ajst-27318	41	7	spf	spf	ADJ
ajst-27318	41	8	male	male	NOUN
ajst-27318	41	9	sprague	sprague	NOUN
ajst-27318	41	10	-	-	PUNCT
ajst-27318	41	11	dawley	dawley	NOUN
ajst-27318	41	12	rats	rat	NOUN
ajst-27318	41	13	,	,	PUNCT
ajst-27318	41	14	weighing	weigh	VERB
ajst-27318	41	15	180	180	NUM
ajst-27318	41	16	-	-	SYM
ajst-27318	41	17	220	220	NUM
ajst-27318	41	18	g	g	NOUN
ajst-27318	41	19	,	,	PUNCT
ajst-27318	41	20	were	be	AUX
ajst-27318	41	21	grown	grow	VERB
ajst-27318	41	22	at	at	ADP
ajst-27318	41	23	room	room	NOUN
ajst-27318	41	24	temperature	temperature	NOUN
ajst-27318	41	25	of	of	ADP
ajst-27318	41	26	(	(	PUNCT
ajst-27318	41	27	24±2)	24±2)	NUM
ajst-27318	41	28	°	°	ADP
ajst-27318	41	29	c	c	NOUN
ajst-27318	41	30	with	with	ADP
ajst-27318	41	31	half	half	NOUN
ajst-27318	41	32	light	light	NOUN
ajst-27318	41	33	and	and	CCONJ
ajst-27318	41	34	half	half	NOUN
ajst-27318	41	35	dark	dark	ADJ
ajst-27318	41	36	.	.	PUNCT
ajst-27318	42	1	the	the	DET
ajst-27318	42	2	rats	rat	NOUN
ajst-27318	42	3	were	be	AUX
ajst-27318	42	4	free	free	ADJ
ajst-27318	42	5	to	to	PART
ajst-27318	42	6	eat	eat	VERB
ajst-27318	42	7	and	and	CCONJ
ajst-27318	42	8	drink	drink	VERB
ajst-27318	42	9	.	.	PUNCT
ajst-27318	43	1	adaptive	adaptive	ADJ
ajst-27318	43	2	feeding	feeding	NOUN
ajst-27318	43	3	was	be	AUX
ajst-27318	43	4	performed	perform	VERB
ajst-27318	43	5	for	for	ADP
ajst-27318	43	6	1	1	NUM
ajst-27318	43	7	week	week	NOUN
ajst-27318	43	8	,	,	PUNCT
ajst-27318	43	9	and	and	CCONJ
ajst-27318	43	10	during	during	ADP
ajst-27318	43	11	the	the	DET
ajst-27318	43	12	adaptive	adaptive	ADJ
ajst-27318	43	13	feeding	feeding	NOUN
ajst-27318	43	14	phase	phase	NOUN
ajst-27318	43	15	,	,	PUNCT
ajst-27318	43	16	all	all	DET
ajst-27318	43	17	rats	rat	NOUN
ajst-27318	43	18	were	be	AUX
ajst-27318	43	19	given	give	VERB
ajst-27318	43	20	a	a	DET
ajst-27318	43	21	common	common	ADJ
ajst-27318	43	22	rodent	rodent	NOUN
ajst-27318	43	23	diet	diet	NOUN
ajst-27318	43	24	.	.	PUNCT
ajst-27318	44	1	at	at	ADP
ajst-27318	44	2	the	the	DET
ajst-27318	44	3	end	end	NOUN
ajst-27318	44	4	of	of	ADP
ajst-27318	44	5	the	the	DET
ajst-27318	44	6	adaptation	adaptation	NOUN
ajst-27318	44	7	feeding	feeding	NOUN
ajst-27318	44	8	,	,	PUNCT
ajst-27318	44	9	the	the	DET
ajst-27318	44	10	rats	rat	NOUN
ajst-27318	44	11	were	be	AUX
ajst-27318	44	12	given	give	VERB
ajst-27318	44	13	high	high	ADJ
ajst-27318	44	14	-	-	PUNCT
ajst-27318	44	15	fat	fat	NOUN
ajst-27318	44	16	diet	diet	NOUN
ajst-27318	44	17	(	(	PUNCT
ajst-27318	44	18	fat	fat	NOUN
ajst-27318	44	19	45	45	NUM
ajst-27318	44	20	%	%	NOUN
ajst-27318	44	21	,	,	PUNCT
ajst-27318	44	22	carbohydrate	carbohydrate	VERB
ajst-27318	44	23	36	36	NUM
ajst-27318	44	24	%	%	NOUN
ajst-27318	44	25	,	,	PUNCT
ajst-27318	44	26	protein	protein	NOUN
ajst-27318	44	27	19	19	NUM
ajst-27318	44	28	%	%	NOUN
ajst-27318	44	29	)	)	PUNCT
ajst-27318	44	30	.	.	PUNCT
ajst-27318	45	1	at	at	ADP
ajst-27318	45	2	the	the	DET
ajst-27318	45	3	fourth	fourth	ADJ
ajst-27318	45	4	week	week	NOUN
ajst-27318	45	5	,	,	PUNCT
ajst-27318	45	6	when	when	SCONJ
ajst-27318	45	7	the	the	DET
ajst-27318	45	8	body	body	NOUN
ajst-27318	45	9	weight	weight	NOUN
ajst-27318	45	10	was	be	AUX
ajst-27318	45	11	more	more	ADJ
ajst-27318	45	12	than	than	ADP
ajst-27318	45	13	29	29	NUM
ajst-27318	45	14	%	%	NOUN
ajst-27318	45	15	of	of	ADP
ajst-27318	45	16	the	the	DET
ajst-27318	45	17	rats	rat	NOUN
ajst-27318	45	18	given	give	VERB
ajst-27318	45	19	normal	normal	ADJ
ajst-27318	45	20	diet	diet	NOUN
ajst-27318	45	21	,	,	PUNCT
ajst-27318	45	22	40	40	NUM
ajst-27318	45	23	rats	rat	NOUN
ajst-27318	45	24	were	be	AUX
ajst-27318	45	25	selected	select	VERB
ajst-27318	45	26	to	to	PART
ajst-27318	45	27	meet	meet	VERB
ajst-27318	45	28	the	the	DET
ajst-27318	45	29	standard	standard	NOUN
ajst-27318	45	30	.	.	PUNCT
ajst-27318	46	1	at	at	ADP
ajst-27318	46	2	the	the	DET
ajst-27318	46	3	same	same	ADJ
ajst-27318	46	4	time	time	NOUN
ajst-27318	46	5	,	,	PUNCT
ajst-27318	46	6	the	the	DET
ajst-27318	46	7	blank	blank	ADJ
ajst-27318	46	8	group	group	NOUN
ajst-27318	46	9	was	be	AUX
ajst-27318	46	10	fed	feed	VERB
ajst-27318	46	11	with	with	ADP
ajst-27318	46	12	normal	normal	ADJ
ajst-27318	46	13	diet	diet	NOUN
ajst-27318	46	14	(	(	PUNCT
ajst-27318	46	15	n=10	n=10	NOUN
ajst-27318	46	16	)	)	PUNCT
ajst-27318	46	17	.	.	PUNCT
ajst-27318	47	1	the	the	DET
ajst-27318	47	2	oa	oa	PROPN
ajst-27318	47	3	model	model	NOUN
ajst-27318	47	4	was	be	AUX
ajst-27318	47	5	established	establish	VERB
ajst-27318	47	6	by	by	ADP
ajst-27318	47	7	anterior	anterior	ADJ
ajst-27318	47	8	cruciate	cruciate	NOUN
ajst-27318	47	9	ligament	ligament	NOUN
ajst-27318	47	10	transection	transection	NOUN
ajst-27318	47	11	and	and	CCONJ
ajst-27318	47	12	medial	medial	ADJ
ajst-27318	47	13	meniscectomy	meniscectomy	NOUN
ajst-27318	47	14	.	.	PUNCT
ajst-27318	48	1	the	the	DET
ajst-27318	48	2	rats	rat	NOUN
ajst-27318	48	3	were	be	AUX
ajst-27318	48	4	anesthetized	anesthetize	VERB
ajst-27318	48	5	and	and	CCONJ
ajst-27318	48	6	the	the	DET
ajst-27318	48	7	hair	hair	NOUN
ajst-27318	48	8	of	of	ADP
ajst-27318	48	9	the	the	DET
ajst-27318	48	10	right	right	ADJ
ajst-27318	48	11	knee	knee	NOUN
ajst-27318	48	12	was	be	AUX
ajst-27318	48	13	clipped	clip	VERB
ajst-27318	48	14	.	.	PUNCT
ajst-27318	49	1	the	the	DET
ajst-27318	49	2	anterior	anterior	ADJ
ajst-27318	49	3	cruciate	cruciate	NOUN
ajst-27318	49	4	ligament	ligament	NOUN
ajst-27318	49	5	was	be	AUX
ajst-27318	49	6	cut	cut	VERB
ajst-27318	49	7	.	.	PUNCT
ajst-27318	50	1	after	after	ADP
ajst-27318	50	2	surgery	surgery	NOUN
ajst-27318	50	3	,	,	PUNCT
ajst-27318	50	4	the	the	DET
ajst-27318	50	5	joints	joint	NOUN
ajst-27318	50	6	were	be	AUX
ajst-27318	50	7	washed	wash	VERB
ajst-27318	50	8	with	with	ADP
ajst-27318	50	9	normal	normal	ADJ
ajst-27318	50	10	saline	saline	NOUN
ajst-27318	50	11	and	and	CCONJ
ajst-27318	50	12	the	the	DET
ajst-27318	50	13	skin	skin	NOUN
ajst-27318	50	14	was	be	AUX
ajst-27318	50	15	sutured	suture	VERB
ajst-27318	50	16	.	.	PUNCT
ajst-27318	51	1	in	in	ADP
ajst-27318	51	2	the	the	DET
ajst-27318	51	3	blank	blank	ADJ
ajst-27318	51	4	group	group	NOUN
ajst-27318	51	5	,	,	PUNCT
ajst-27318	51	6	the	the	DET
ajst-27318	51	7	anterior	anterior	ADJ
ajst-27318	51	8	cruciate	cruciate	NOUN
ajst-27318	51	9	ligament	ligament	NOUN
ajst-27318	51	10	was	be	AUX
ajst-27318	51	11	exposed	expose	VERB
ajst-27318	51	12	but	but	CCONJ
ajst-27318	51	13	not	not	PART
ajst-27318	51	14	cut	cut	VERB
ajst-27318	51	15	.	.	PUNCT
ajst-27318	52	1	after	after	ADP
ajst-27318	52	2	the	the	DET
ajst-27318	52	3	operation	operation	NOUN
ajst-27318	52	4	,	,	PUNCT
ajst-27318	52	5	the	the	DET
ajst-27318	52	6	obese	obese	NOUN
ajst-27318	52	7	oa	oa	PROPN
ajst-27318	52	8	model	model	NOUN
ajst-27318	52	9	rats	rat	NOUN
ajst-27318	52	10	were	be	AUX
ajst-27318	52	11	randomly	randomly	ADV
ajst-27318	52	12	divided	divide	VERB
ajst-27318	52	13	into	into	ADP
ajst-27318	52	14	model	model	NOUN
ajst-27318	52	15	group	group	NOUN
ajst-27318	52	16	(	(	PUNCT
ajst-27318	52	17	oa	oa	PROPN
ajst-27318	52	18	)	)	PUNCT
ajst-27318	52	19	and	and	CCONJ
ajst-27318	52	20	radix	radix	PROPN
ajst-27318	52	21	achyrandii	achyrandii	PROPN
ajst-27318	52	22	polysaccharide	polysaccharide	NOUN
ajst-27318	52	23	group	group	NOUN
ajst-27318	52	24	(	(	PUNCT
ajst-27318	52	25	200	200	NUM
ajst-27318	52	26	mg	mg	PROPN
ajst-27318	52	27	/	/	SYM
ajst-27318	52	28	kg	kg	PROPN
ajst-27318	52	29	,	,	PUNCT
ajst-27318	52	30	rap	rap	NOUN
ajst-27318	52	31	)	)	PUNCT
ajst-27318	52	32	,	,	PUNCT
ajst-27318	52	33	with	with	ADP
ajst-27318	52	34	10	10	NUM
ajst-27318	52	35	rats	rat	NOUN
ajst-27318	52	36	in	in	ADP
ajst-27318	52	37	each	each	DET
ajst-27318	52	38	group	group	NOUN
ajst-27318	52	39	.	.	PUNCT
ajst-27318	53	1	the	the	DET
ajst-27318	53	2	rats	rat	NOUN
ajst-27318	53	3	in	in	ADP
ajst-27318	53	4	the	the	DET
ajst-27318	53	5	oa	oa	PROPN
ajst-27318	53	6	model	model	NOUN
ajst-27318	53	7	group	group	NOUN
ajst-27318	53	8	and	and	CCONJ
ajst-27318	53	9	the	the	DET
ajst-27318	53	10	blank	blank	ADJ
ajst-27318	53	11	group	group	NOUN
ajst-27318	53	12	were	be	AUX
ajst-27318	53	13	given	give	VERB
ajst-27318	53	14	the	the	DET
ajst-27318	53	15	same	same	ADJ
ajst-27318	53	16	volume	volume	NOUN
ajst-27318	53	17	of	of	ADP
ajst-27318	53	18	normal	normal	ADJ
ajst-27318	53	19	saline	saline	NOUN
ajst-27318	53	20	,	,	PUNCT
ajst-27318	53	21	and	and	CCONJ
ajst-27318	53	22	the	the	DET
ajst-27318	53	23	rats	rat	NOUN
ajst-27318	53	24	in	in	ADP
ajst-27318	53	25	the	the	DET
ajst-27318	53	26	rap	rap	NOUN
ajst-27318	53	27	group	group	NOUN
ajst-27318	53	28	were	be	AUX
ajst-27318	53	29	given	give	VERB
ajst-27318	53	30	the	the	DET
ajst-27318	53	31	corresponding	correspond	VERB
ajst-27318	53	32	drugs	drug	NOUN
ajst-27318	53	33	by	by	ADP
ajst-27318	53	34	gavage	gavage	NOUN
ajst-27318	53	35	once	once	ADV
ajst-27318	53	36	a	a	DET
ajst-27318	53	37	day	day	NOUN
ajst-27318	53	38	for	for	ADP
ajst-27318	53	39	4	4	NUM
ajst-27318	53	40	weeks	week	NOUN
ajst-27318	53	41	.	.	PUNCT
ajst-27318	54	1	this	this	PRON
ajst-27318	54	2	continued	continue	VERB
ajst-27318	54	3	until	until	ADP
ajst-27318	54	4	the	the	DET
ajst-27318	54	5	end	end	NOUN
ajst-27318	54	6	of	of	ADP
ajst-27318	54	7	the	the	DET
ajst-27318	54	8	8	8	NUM
ajst-27318	54	9	-	-	PUNCT
ajst-27318	54	10	week	week	NOUN
ajst-27318	54	11	experiment	experiment	NOUN
ajst-27318	54	12	.	.	PUNCT
ajst-27318	55	1	all	all	DET
ajst-27318	55	2	animals	animal	NOUN
ajst-27318	55	3	were	be	AUX
ajst-27318	55	4	fasted	fast	VERB
ajst-27318	55	5	for	for	ADP
ajst-27318	55	6	12	12	NUM
ajst-27318	55	7	h	h	NOUN
ajst-27318	55	8	before	before	ADP
ajst-27318	55	9	the	the	DET
ajst-27318	55	10	last	last	ADJ
ajst-27318	55	11	administration	administration	NOUN
ajst-27318	55	12	,	,	PUNCT
ajst-27318	55	13	and	and	CCONJ
ajst-27318	55	14	mice	mouse	NOUN
ajst-27318	55	15	were	be	AUX
ajst-27318	55	16	anesthetized	anesthetize	VERB
ajst-27318	55	17	1.5	1.5	NUM
ajst-27318	55	18	h	h	NOUN
ajst-27318	55	19	after	after	SCONJ
ajst-27318	55	20	the	the	DET
ajst-27318	55	21	last	last	ADJ
ajst-27318	55	22	administration	administration	NOUN
ajst-27318	55	23	and	and	CCONJ
ajst-27318	55	24	blood	blood	NOUN
ajst-27318	55	25	samples	sample	NOUN
ajst-27318	55	26	were	be	AUX
ajst-27318	55	27	collected	collect	VERB
ajst-27318	55	28	.	.	PUNCT
ajst-27318	56	1	the	the	DET
ajst-27318	56	2	target	target	NOUN
ajst-27318	56	3	knee	knee	NOUN
ajst-27318	56	4	tissues	tissue	NOUN
ajst-27318	56	5	were	be	AUX
ajst-27318	56	6	collected	collect	VERB
ajst-27318	56	7	after	after	SCONJ
ajst-27318	56	8	the	the	DET
ajst-27318	56	9	rats	rat	NOUN
ajst-27318	56	10	were	be	AUX
ajst-27318	56	11	euthanized	euthanize	VERB
ajst-27318	56	12	with	with	ADP
ajst-27318	56	13	carbon	carbon	NOUN
ajst-27318	56	14	dioxide	dioxide	NOUN
ajst-27318	56	15	.	.	PUNCT
ajst-27318	57	1	2.3	2.3	NUM
ajst-27318	57	2	.	.	PUNCT
ajst-27318	58	1	serum	serum	VERB
ajst-27318	58	2	biochemical	biochemical	ADJ
ajst-27318	58	3	indicators	indicator	NOUN
ajst-27318	58	4	serum	serum	VERB
ajst-27318	58	5	tg	tg	PROPN
ajst-27318	58	6	,	,	PUNCT
ajst-27318	58	7	tc	tc	NOUN
ajst-27318	58	8	,	,	PUNCT
ajst-27318	58	9	hdl	hdl	PROPN
ajst-27318	58	10	-	-	PUNCT
ajst-27318	58	11	c	c	PROPN
ajst-27318	58	12	and	and	CCONJ
ajst-27318	58	13	ldl	ldl	PROPN
ajst-27318	58	14	-	-	PUNCT
ajst-27318	58	15	c	c	NOUN
ajst-27318	58	16	levels	level	NOUN
ajst-27318	58	17	were	be	AUX
ajst-27318	58	18	measured	measure	VERB
ajst-27318	58	19	by	by	ADP
ajst-27318	58	20	biochemical	biochemical	ADJ
ajst-27318	58	21	analyzer	analyzer	NOUN
ajst-27318	58	22	according	accord	VERB
ajst-27318	58	23	to	to	ADP
ajst-27318	58	24	the	the	DET
ajst-27318	58	25	instructions	instruction	NOUN
ajst-27318	58	26	of	of	ADP
ajst-27318	58	27	each	each	DET
ajst-27318	58	28	kit	kit	NOUN
ajst-27318	58	29	.	.	PUNCT
ajst-27318	59	1	the	the	DET
ajst-27318	59	2	activity	activity	NOUN
ajst-27318	59	3	of	of	ADP
ajst-27318	59	4	sod	sod	NOUN
ajst-27318	59	5	and	and	CCONJ
ajst-27318	59	6	the	the	DET
ajst-27318	59	7	levels	level	NOUN
ajst-27318	59	8	of	of	ADP
ajst-27318	59	9	mda	mda	PROPN
ajst-27318	59	10	,	,	PUNCT
ajst-27318	59	11	tnf	tnf	PROPN
ajst-27318	59	12	-	-	PUNCT
ajst-27318	59	13	α	α	PROPN
ajst-27318	59	14	and	and	CCONJ
ajst-27318	59	15	il-1β	il-1β	PROPN
ajst-27318	59	16	in	in	ADP
ajst-27318	59	17	serum	serum	NOUN
ajst-27318	59	18	were	be	AUX
ajst-27318	59	19	detected	detect	VERB
ajst-27318	59	20	by	by	ADP
ajst-27318	59	21	elisa	elisa	PROPN
ajst-27318	59	22	kit	kit	PROPN
ajst-27318	59	23	.	.	PROPN
ajst-27318	60	1	2.4	2.4	NUM
ajst-27318	60	2	.	.	PUNCT
ajst-27318	61	1	histopathological	histopathological	ADJ
ajst-27318	61	2	examination	examination	NOUN
ajst-27318	61	3	the	the	DET
ajst-27318	61	4	morphological	morphological	ADJ
ajst-27318	61	5	changes	change	NOUN
ajst-27318	61	6	of	of	ADP
ajst-27318	61	7	articular	articular	ADJ
ajst-27318	61	8	cartilage	cartilage	NOUN
ajst-27318	61	9	were	be	AUX
ajst-27318	61	10	observed	observe	VERB
ajst-27318	61	11	by	by	ADP
ajst-27318	61	12	h&e	h&e	PROPN
ajst-27318	61	13	staining，the	staining，the	DET
ajst-27318	61	14	experimental	experimental	ADJ
ajst-27318	61	15	procedure	procedure	NOUN
ajst-27318	61	16	was	be	AUX
ajst-27318	61	17	decalcification	decalcification	NOUN
ajst-27318	61	18	,	,	PUNCT
ajst-27318	61	19	paraffin	paraffin	NOUN
ajst-27318	61	20	embedding	embed	VERB
ajst-27318	61	21	,	,	PUNCT
ajst-27318	61	22	slice	slice	NOUN
ajst-27318	61	23	-	-	PUNCT
ajst-27318	61	24	dye	dye	NOUN
ajst-27318	61	25	-	-	PUNCT
ajst-27318	61	26	observationimmobilization	observationimmobilization	NOUN
ajst-27318	61	27	,	,	PUNCT
ajst-27318	61	28	and	and	CCONJ
ajst-27318	61	29	the	the	DET
ajst-27318	61	30	operation	operation	NOUN
ajst-27318	61	31	was	be	AUX
ajst-27318	61	32	strictly	strictly	ADV
ajst-27318	61	33	performed	perform	VERB
ajst-27318	61	34	according	accord	VERB
ajst-27318	61	35	to	to	ADP
ajst-27318	61	36	the	the	DET
ajst-27318	61	37	operating	operating	NOUN
ajst-27318	61	38	instructions	instruction	NOUN
ajst-27318	61	39	.	.	PUNCT
ajst-27318	62	1	the	the	DET
ajst-27318	62	2	cartilage	cartilage	NOUN
ajst-27318	62	3	tissue	tissue	NOUN
ajst-27318	62	4	of	of	ADP
ajst-27318	62	5	5	5	NUM
ajst-27318	62	6	rats	rat	NOUN
ajst-27318	62	7	in	in	ADP
ajst-27318	62	8	each	each	DET
ajst-27318	62	9	group	group	NOUN
ajst-27318	62	10	was	be	AUX
ajst-27318	62	11	randomly	randomly	ADV
ajst-27318	62	12	taken	take	VERB
ajst-27318	62	13	,	,	PUNCT
ajst-27318	62	14	and	and	CCONJ
ajst-27318	62	15	the	the	DET
ajst-27318	62	16	protein	protein	NOUN
ajst-27318	62	17	expressions	expression	NOUN
ajst-27318	62	18	of	of	ADP
ajst-27318	62	19	mmp-3	mmp-3	NUM
ajst-27318	62	20	and	and	CCONJ
ajst-27318	62	21	timp-1	timp-1	NUM
ajst-27318	62	22	were	be	AUX
ajst-27318	62	23	detected	detect	VERB
ajst-27318	62	24	by	by	ADP
ajst-27318	62	25	western	western	ADJ
ajst-27318	62	26	blotting	blotting	NOUN
ajst-27318	62	27	.	.	PUNCT
ajst-27318	63	1	2.5	2.5	NUM
ajst-27318	63	2	.	.	PUNCT
ajst-27318	64	1	data	datum	NOUN
ajst-27318	64	2	statistics	statistic	NOUN
ajst-27318	64	3	and	and	CCONJ
ajst-27318	64	4	analysis	analysis	NOUN
ajst-27318	64	5	data	datum	NOUN
ajst-27318	64	6	were	be	AUX
ajst-27318	64	7	analyzed	analyze	VERB
ajst-27318	64	8	and	and	CCONJ
ajst-27318	64	9	plotted	plot	VERB
ajst-27318	64	10	by	by	ADP
ajst-27318	64	11	r	r	NOUN
ajst-27318	64	12	software	software	NOUN
ajst-27318	64	13	.	.	PUNCT
ajst-27318	65	1	the	the	DET
ajst-27318	65	2	experimental	experimental	ADJ
ajst-27318	65	3	data	datum	NOUN
ajst-27318	65	4	were	be	AUX
ajst-27318	65	5	expressed	express	VERB
ajst-27318	65	6	as	as	ADP
ajst-27318	65	7	mean	mean	NOUN
ajst-27318	65	8	±	±	NUM
ajst-27318	65	9	standard	standard	ADJ
ajst-27318	65	10	deviation	deviation	NOUN
ajst-27318	65	11	,	,	PUNCT
ajst-27318	65	12	and	and	CCONJ
ajst-27318	65	13	ordinary	ordinary	ADJ
ajst-27318	65	14	one	one	NUM
ajst-27318	65	15	-	-	PUNCT
ajst-27318	65	16	way	way	NOUN
ajst-27318	65	17	analysis	analysis	NOUN
ajst-27318	65	18	of	of	ADP
ajst-27318	65	19	variance	variance	NOUN
ajst-27318	65	20	was	be	AUX
ajst-27318	65	21	used	use	VERB
ajst-27318	65	22	between	between	ADP
ajst-27318	65	23	groups	group	NOUN
ajst-27318	65	24	.	.	PUNCT
ajst-27318	66	1	p<0.05	p<0.05	NOUN
ajst-27318	66	2	indicates	indicate	VERB
ajst-27318	66	3	a	a	DET
ajst-27318	66	4	significant	significant	ADJ
ajst-27318	66	5	difference	difference	NOUN
ajst-27318	66	6	,	,	PUNCT
ajst-27318	66	7	p<0.01	p<0.01	PROPN
ajst-27318	66	8	indicates	indicate	VERB
ajst-27318	66	9	a	a	DET
ajst-27318	66	10	very	very	ADV
ajst-27318	66	11	significant	significant	ADJ
ajst-27318	66	12	difference	difference	NOUN
ajst-27318	66	13	,	,	PUNCT
ajst-27318	66	14	p<0.001	p<0.001	PROPN
ajst-27318	66	15	was	be	AUX
ajst-27318	66	16	considered	consider	VERB
ajst-27318	66	17	to	to	PART
ajst-27318	66	18	be	be	AUX
ajst-27318	66	19	highly	highly	ADV
ajst-27318	66	20	significant	significant	ADJ
ajst-27318	66	21	.	.	PUNCT
ajst-27318	67	1	3	3	X
ajst-27318	67	2	.	.	NOUN
ajst-27318	67	3	results	result	VERB
ajst-27318	67	4	3.1	3.1	NUM
ajst-27318	67	5	.	.	PUNCT
ajst-27318	68	1	effects	effect	NOUN
ajst-27318	68	2	of	of	ADP
ajst-27318	68	3	rap	rap	NOUN
ajst-27318	68	4	on	on	ADP
ajst-27318	68	5	blood	blood	NOUN
ajst-27318	68	6	lipids	lipid	NOUN
ajst-27318	68	7	in	in	ADP
ajst-27318	68	8	oa	oa	PROPN
ajst-27318	68	9	rats	rat	NOUN
ajst-27318	68	10	as	as	SCONJ
ajst-27318	68	11	shown	show	VERB
ajst-27318	68	12	in	in	ADP
ajst-27318	68	13	fig.1	fig.1	PROPN
ajst-27318	68	14	,	,	PUNCT
ajst-27318	68	15	compared	compare	VERB
ajst-27318	68	16	with	with	ADP
ajst-27318	68	17	the	the	DET
ajst-27318	68	18	blank	blank	ADJ
ajst-27318	68	19	group	group	NOUN
ajst-27318	68	20	,	,	PUNCT
ajst-27318	68	21	the	the	DET
ajst-27318	68	22	serum	serum	NOUN
ajst-27318	68	23	levels	level	NOUN
ajst-27318	68	24	of	of	ADP
ajst-27318	68	25	tg	tg	PROPN
ajst-27318	68	26	,	,	PUNCT
ajst-27318	68	27	tc	tc	NOUN
ajst-27318	68	28	and	and	CCONJ
ajst-27318	68	29	ldl	ldl	NOUN
ajst-27318	68	30	-	-	PUNCT
ajst-27318	68	31	c	c	NOUN
ajst-27318	68	32	in	in	ADP
ajst-27318	68	33	the	the	DET
ajst-27318	68	34	model	model	NOUN
ajst-27318	68	35	group	group	NOUN
ajst-27318	68	36	were	be	AUX
ajst-27318	68	37	significantly	significantly	ADV
ajst-27318	68	38	increased	increase	VERB
ajst-27318	68	39	,	,	PUNCT
ajst-27318	68	40	and	and	CCONJ
ajst-27318	68	41	the	the	DET
ajst-27318	68	42	level	level	NOUN
ajst-27318	68	43	of	of	ADP
ajst-27318	68	44	hdl	hdl	PROPN
ajst-27318	68	45	-	-	PUNCT
ajst-27318	68	46	c	c	PROPN
ajst-27318	68	47	was	be	AUX
ajst-27318	68	48	significantly	significantly	ADV
ajst-27318	68	49	decreased	decrease	VERB
ajst-27318	68	50	(	(	PUNCT
ajst-27318	68	51	p	p	X
ajst-27318	68	52	<	<	X
ajst-27318	68	53	0.05	0.05	NUM
ajst-27318	68	54	)	)	PUNCT
ajst-27318	68	55	.	.	PUNCT
ajst-27318	69	1	compared	compare	VERB
ajst-27318	69	2	with	with	ADP
ajst-27318	69	3	the	the	DET
ajst-27318	69	4	model	model	NOUN
ajst-27318	69	5	group	group	NOUN
ajst-27318	69	6	,	,	PUNCT
ajst-27318	69	7	the	the	DET
ajst-27318	69	8	serum	serum	NOUN
ajst-27318	69	9	levels	level	NOUN
ajst-27318	69	10	of	of	ADP
ajst-27318	69	11	tg	tg	PROPN
ajst-27318	69	12	,	,	PUNCT
ajst-27318	69	13	tc	tc	NOUN
ajst-27318	69	14	and	and	CCONJ
ajst-27318	69	15	ldl	ldl	PROPN
ajst-27318	69	16	-	-	PUNCT
ajst-27318	69	17	c	c	PROPN
ajst-27318	69	18	were	be	AUX
ajst-27318	69	19	significantly	significantly	ADV
ajst-27318	69	20	decreased	decrease	VERB
ajst-27318	69	21	,	,	PUNCT
ajst-27318	69	22	and	and	CCONJ
ajst-27318	69	23	the	the	DET
ajst-27318	69	24	level	level	NOUN
ajst-27318	69	25	of	of	ADP
ajst-27318	69	26	hdl	hdl	PROPN
ajst-27318	69	27	-	-	PUNCT
ajst-27318	69	28	c	c	PROPN
ajst-27318	69	29	was	be	AUX
ajst-27318	69	30	significantly	significantly	ADV
ajst-27318	69	31	increased	increase	VERB
ajst-27318	69	32	in	in	ADP
ajst-27318	69	33	the	the	DET
ajst-27318	69	34	rap	rap	NOUN
ajst-27318	69	35	group	group	NOUN
ajst-27318	69	36	(	(	PUNCT
ajst-27318	69	37	p	p	X
ajst-27318	69	38	<	<	X
ajst-27318	69	39	0.05	0.05	NUM
ajst-27318	69	40	)	)	PUNCT
ajst-27318	69	41	.	.	PUNCT
ajst-27318	70	1	figure	figure	NOUN
ajst-27318	70	2	1	1	NUM
ajst-27318	70	3	.	.	PUNCT
ajst-27318	71	1	effects	effect	NOUN
ajst-27318	71	2	of	of	ADP
ajst-27318	71	3	rap	rap	NOUN
ajst-27318	71	4	on	on	ADP
ajst-27318	71	5	blood	blood	NOUN
ajst-27318	71	6	lipids	lipid	NOUN
ajst-27318	71	7	in	in	ADP
ajst-27318	71	8	rats	rat	NOUN
ajst-27318	71	9	3.2	3.2	NUM
ajst-27318	71	10	.	.	PUNCT
ajst-27318	72	1	effects	effect	NOUN
ajst-27318	72	2	of	of	ADP
ajst-27318	72	3	rap	rap	NOUN
ajst-27318	72	4	on	on	ADP
ajst-27318	72	5	antioxidant	antioxidant	ADJ
ajst-27318	72	6	and	and	CCONJ
ajst-27318	72	7	antiinflammatory	antiinflammatory	NOUN
ajst-27318	72	8	properties	property	NOUN
ajst-27318	72	9	in	in	ADP
ajst-27318	72	10	oa	oa	ADP
ajst-27318	72	11	rats	rat	NOUN
ajst-27318	72	12	compared	compare	VERB
ajst-27318	72	13	with	with	ADP
ajst-27318	72	14	the	the	DET
ajst-27318	72	15	blank	blank	ADJ
ajst-27318	72	16	group	group	NOUN
ajst-27318	72	17	,	,	PUNCT
ajst-27318	72	18	the	the	DET
ajst-27318	72	19	serum	serum	NOUN
ajst-27318	72	20	sod	sod	NOUN
ajst-27318	72	21	activity	activity	NOUN
ajst-27318	72	22	of	of	ADP
ajst-27318	72	23	the	the	DET
ajst-27318	72	24	model	model	NOUN
ajst-27318	72	25	group	group	NOUN
ajst-27318	72	26	was	be	AUX
ajst-27318	72	27	significantly	significantly	ADV
ajst-27318	72	28	decreased	decrease	VERB
ajst-27318	72	29	,	,	PUNCT
ajst-27318	72	30	and	and	CCONJ
ajst-27318	72	31	the	the	DET
ajst-27318	72	32	levels	level	NOUN
ajst-27318	72	33	of	of	ADP
ajst-27318	72	34	mda	mda	PROPN
ajst-27318	72	35	,	,	PUNCT
ajst-27318	72	36	tnf	tnf	PROPN
ajst-27318	72	37	-	-	PUNCT
ajst-27318	72	38	α	α	PROPN
ajst-27318	72	39	and	and	CCONJ
ajst-27318	72	40	il-1β	il-1β	PROPN
ajst-27318	72	41	were	be	AUX
ajst-27318	72	42	significantly	significantly	ADV
ajst-27318	72	43	increased	increase	VERB
ajst-27318	72	44	.	.	PUNCT
ajst-27318	73	1	compared	compare	VERB
ajst-27318	73	2	with	with	ADP
ajst-27318	73	3	the	the	DET
ajst-27318	73	4	model	model	NOUN
ajst-27318	73	5	group	group	NOUN
ajst-27318	73	6	,	,	PUNCT
ajst-27318	73	7	the	the	DET
ajst-27318	73	8	activity	activity	NOUN
ajst-27318	73	9	of	of	ADP
ajst-27318	73	10	sod	sod	NOUN
ajst-27318	73	11	was	be	AUX
ajst-27318	73	12	significantly	significantly	ADV
ajst-27318	73	13	increased	increase	VERB
ajst-27318	73	14	,	,	PUNCT
ajst-27318	73	15	and	and	CCONJ
ajst-27318	73	16	the	the	DET
ajst-27318	73	17	levels	level	NOUN
ajst-27318	73	18	of	of	ADP
ajst-27318	73	19	mda	mda	PROPN
ajst-27318	73	20	,	,	PUNCT
ajst-27318	73	21	tnf	tnf	PROPN
ajst-27318	73	22	-	-	PUNCT
ajst-27318	73	23	α	α	PROPN
ajst-27318	73	24	and	and	CCONJ
ajst-27318	73	25	il-1β	il-1β	PROPN
ajst-27318	73	26	were	be	AUX
ajst-27318	73	27	significantly	significantly	ADV
ajst-27318	73	28	decreased	decrease	VERB
ajst-27318	73	29	in	in	ADP
ajst-27318	73	30	the	the	DET
ajst-27318	73	31	rap	rap	NOUN
ajst-27318	73	32	group	group	NOUN
ajst-27318	73	33	(	(	PUNCT
ajst-27318	73	34	fig	fig	NOUN
ajst-27318	73	35	.	.	PUNCT
ajst-27318	74	1	2	2	NUM
ajst-27318	74	2	)	)	PUNCT
ajst-27318	74	3	.	.	PUNCT
ajst-27318	75	1	76	76	NUM
ajst-27318	75	2	figure	figure	NOUN
ajst-27318	75	3	2	2	NUM
ajst-27318	75	4	.	.	PUNCT
ajst-27318	75	5	effect	effect	NOUN
ajst-27318	75	6	of	of	ADP
ajst-27318	75	7	artemisia	artemisia	NOUN
ajst-27318	75	8	selengensis	selengensis	NOUN
ajst-27318	75	9	cellulose	cellulose	NOUN
ajst-27318	75	10	on	on	ADP
ajst-27318	75	11	blood	blood	NOUN
ajst-27318	75	12	lipids	lipid	NOUN
ajst-27318	75	13	in	in	ADP
ajst-27318	75	14	diabetic	diabetic	ADJ
ajst-27318	75	15	mice	mouse	NOUN
ajst-27318	75	16	3.3	3.3	NUM
ajst-27318	75	17	.	.	PUNCT
ajst-27318	76	1	effect	effect	NOUN
ajst-27318	76	2	of	of	ADP
ajst-27318	76	3	rap	rap	NOUN
ajst-27318	76	4	on	on	ADP
ajst-27318	76	5	histopathology	histopathology	NOUN
ajst-27318	76	6	of	of	ADP
ajst-27318	76	7	articular	articular	ADJ
ajst-27318	76	8	cartilage	cartilage	NOUN
ajst-27318	76	9	in	in	ADP
ajst-27318	76	10	oa	oa	ADP
ajst-27318	76	11	rats	rat	NOUN
ajst-27318	76	12	in	in	ADP
ajst-27318	76	13	the	the	DET
ajst-27318	76	14	blank	blank	ADJ
ajst-27318	76	15	group	group	NOUN
ajst-27318	76	16	,	,	PUNCT
ajst-27318	76	17	the	the	DET
ajst-27318	76	18	cartilage	cartilage	NOUN
ajst-27318	76	19	tissue	tissue	NOUN
ajst-27318	76	20	cells	cell	NOUN
ajst-27318	76	21	were	be	AUX
ajst-27318	76	22	closely	closely	ADV
ajst-27318	76	23	arranged	arrange	VERB
ajst-27318	76	24	,	,	PUNCT
ajst-27318	76	25	the	the	DET
ajst-27318	76	26	cartilage	cartilage	NOUN
ajst-27318	76	27	surface	surface	NOUN
ajst-27318	76	28	was	be	AUX
ajst-27318	76	29	smooth	smooth	ADJ
ajst-27318	76	30	and	and	CCONJ
ajst-27318	76	31	the	the	DET
ajst-27318	76	32	tide	tide	NOUN
ajst-27318	76	33	line	line	NOUN
ajst-27318	76	34	was	be	AUX
ajst-27318	76	35	clear	clear	ADJ
ajst-27318	76	36	.	.	PUNCT
ajst-27318	77	1	in	in	ADP
ajst-27318	77	2	the	the	DET
ajst-27318	77	3	model	model	NOUN
ajst-27318	77	4	group	group	NOUN
ajst-27318	77	5	,	,	PUNCT
ajst-27318	77	6	the	the	DET
ajst-27318	77	7	staining	stain	VERB
ajst-27318	77	8	around	around	ADP
ajst-27318	77	9	the	the	DET
ajst-27318	77	10	chondrocytes	chondrocyte	NOUN
ajst-27318	77	11	became	become	VERB
ajst-27318	77	12	light	light	ADJ
ajst-27318	77	13	,	,	PUNCT
ajst-27318	77	14	the	the	DET
ajst-27318	77	15	cells	cell	NOUN
ajst-27318	77	16	were	be	AUX
ajst-27318	77	17	arranged	arrange	VERB
ajst-27318	77	18	loosely	loosely	ADV
ajst-27318	77	19	,	,	PUNCT
ajst-27318	77	20	and	and	CCONJ
ajst-27318	77	21	the	the	DET
ajst-27318	77	22	tide	tide	NOUN
ajst-27318	77	23	line	line	NOUN
ajst-27318	77	24	was	be	AUX
ajst-27318	77	25	blurred	blur	VERB
ajst-27318	77	26	or	or	CCONJ
ajst-27318	77	27	broken	break	VERB
ajst-27318	77	28	.	.	PUNCT
ajst-27318	78	1	compared	compare	VERB
ajst-27318	78	2	with	with	ADP
ajst-27318	78	3	the	the	DET
ajst-27318	78	4	model	model	NOUN
ajst-27318	78	5	group	group	NOUN
ajst-27318	78	6	,	,	PUNCT
ajst-27318	78	7	the	the	DET
ajst-27318	78	8	arrangement	arrangement	NOUN
ajst-27318	78	9	of	of	ADP
ajst-27318	78	10	chondrocytes	chondrocyte	NOUN
ajst-27318	78	11	and	and	CCONJ
ajst-27318	78	12	the	the	DET
ajst-27318	78	13	clarity	clarity	NOUN
ajst-27318	78	14	of	of	ADP
ajst-27318	78	15	the	the	DET
ajst-27318	78	16	tideline	tideline	NOUN
ajst-27318	78	17	in	in	ADP
ajst-27318	78	18	the	the	DET
ajst-27318	78	19	rap	rap	NOUN
ajst-27318	78	20	group	group	NOUN
ajst-27318	78	21	were	be	AUX
ajst-27318	78	22	improved	improve	VERB
ajst-27318	78	23	,	,	PUNCT
ajst-27318	78	24	although	although	SCONJ
ajst-27318	78	25	the	the	DET
ajst-27318	78	26	cell	cell	NOUN
ajst-27318	78	27	accumulation	accumulation	NOUN
ajst-27318	78	28	and	and	CCONJ
ajst-27318	78	29	the	the	DET
ajst-27318	78	30	surface	surface	NOUN
ajst-27318	78	31	were	be	AUX
ajst-27318	78	32	blurred	blur	VERB
ajst-27318	78	33	,	,	PUNCT
ajst-27318	78	34	but	but	CCONJ
ajst-27318	78	35	the	the	DET
ajst-27318	78	36	continuity	continuity	NOUN
ajst-27318	78	37	was	be	AUX
ajst-27318	78	38	acceptable	acceptable	ADJ
ajst-27318	78	39	.	.	PUNCT
ajst-27318	79	1	3.4	3.4	NUM
ajst-27318	79	2	.	.	PUNCT
ajst-27318	79	3	effects	effect	NOUN
ajst-27318	79	4	of	of	ADP
ajst-27318	79	5	rap	rap	NOUN
ajst-27318	79	6	on	on	ADP
ajst-27318	79	7	the	the	DET
ajst-27318	79	8	expression	expression	NOUN
ajst-27318	79	9	of	of	ADP
ajst-27318	79	10	mmp3	mmp3	NOUN
ajst-27318	79	11	and	and	CCONJ
ajst-27318	79	12	timp-1	timp-1	NUM
ajst-27318	79	13	protein	protein	NOUN
ajst-27318	79	14	in	in	ADP
ajst-27318	79	15	oa	oa	ADP
ajst-27318	79	16	rats	rat	NOUN
ajst-27318	79	17	compared	compare	VERB
ajst-27318	79	18	with	with	ADP
ajst-27318	79	19	the	the	DET
ajst-27318	79	20	blank	blank	ADJ
ajst-27318	79	21	group	group	NOUN
ajst-27318	79	22	,	,	PUNCT
ajst-27318	79	23	the	the	DET
ajst-27318	79	24	expression	expression	NOUN
ajst-27318	79	25	of	of	ADP
ajst-27318	79	26	mmp-3	mmp-3	NUM
ajst-27318	79	27	and	and	CCONJ
ajst-27318	79	28	timp-1	timp-1	NUM
ajst-27318	79	29	protein	protein	NOUN
ajst-27318	79	30	in	in	ADP
ajst-27318	79	31	articular	articular	ADJ
ajst-27318	79	32	cartilage	cartilage	NOUN
ajst-27318	79	33	tissue	tissue	NOUN
ajst-27318	79	34	of	of	ADP
ajst-27318	79	35	the	the	DET
ajst-27318	79	36	model	model	NOUN
ajst-27318	79	37	group	group	NOUN
ajst-27318	79	38	was	be	AUX
ajst-27318	79	39	significantly	significantly	ADV
ajst-27318	79	40	increased	increase	VERB
ajst-27318	79	41	.	.	PUNCT
ajst-27318	80	1	compared	compare	VERB
ajst-27318	80	2	with	with	ADP
ajst-27318	80	3	the	the	DET
ajst-27318	80	4	model	model	NOUN
ajst-27318	80	5	group	group	NOUN
ajst-27318	80	6	,	,	PUNCT
ajst-27318	80	7	the	the	DET
ajst-27318	80	8	protein	protein	NOUN
ajst-27318	80	9	expression	expression	NOUN
ajst-27318	80	10	of	of	ADP
ajst-27318	80	11	mmp-3	mmp-3	NUM
ajst-27318	80	12	and	and	CCONJ
ajst-27318	80	13	timp-1	timp-1	NUM
ajst-27318	80	14	in	in	ADP
ajst-27318	80	15	the	the	DET
ajst-27318	80	16	rap	rap	NOUN
ajst-27318	80	17	group	group	NOUN
ajst-27318	80	18	was	be	AUX
ajst-27318	80	19	significantly	significantly	ADV
ajst-27318	80	20	decreased	decrease	VERB
ajst-27318	80	21	.	.	PUNCT
ajst-27318	81	1	4	4	X
ajst-27318	81	2	.	.	X
ajst-27318	81	3	summary	summary	NOUN
ajst-27318	81	4	overweight	overweight	NOUN
ajst-27318	81	5	and	and	CCONJ
ajst-27318	81	6	obesity	obesity	NOUN
ajst-27318	81	7	are	be	AUX
ajst-27318	81	8	one	one	NUM
ajst-27318	81	9	of	of	ADP
ajst-27318	81	10	the	the	DET
ajst-27318	81	11	important	important	ADJ
ajst-27318	81	12	risk	risk	NOUN
ajst-27318	81	13	factors	factor	NOUN
ajst-27318	81	14	for	for	ADP
ajst-27318	81	15	the	the	DET
ajst-27318	81	16	occurrence	occurrence	NOUN
ajst-27318	81	17	and	and	CCONJ
ajst-27318	81	18	development	development	NOUN
ajst-27318	81	19	of	of	ADP
ajst-27318	81	20	knee	knee	NOUN
ajst-27318	81	21	oa	oa	INTJ
ajst-27318	81	22	.	.	PROPN
ajst-27318	81	23	obesity	obesity	NOUN
ajst-27318	81	24	can	can	AUX
ajst-27318	81	25	lead	lead	VERB
ajst-27318	81	26	to	to	ADP
ajst-27318	81	27	increased	increase	VERB
ajst-27318	81	28	mechanical	mechanical	ADJ
ajst-27318	81	29	stress	stress	NOUN
ajst-27318	81	30	of	of	ADP
ajst-27318	81	31	the	the	DET
ajst-27318	81	32	joint	joint	ADJ
ajst-27318	81	33	,	,	PUNCT
ajst-27318	81	34	abnormal	abnormal	ADJ
ajst-27318	81	35	degradation	degradation	NOUN
ajst-27318	81	36	of	of	ADP
ajst-27318	81	37	articular	articular	ADJ
ajst-27318	81	38	cartilage	cartilage	NOUN
ajst-27318	81	39	,	,	PUNCT
ajst-27318	81	40	bone	bone	NOUN
ajst-27318	81	41	loss	loss	NOUN
ajst-27318	81	42	,	,	PUNCT
ajst-27318	81	43	and	and	CCONJ
ajst-27318	81	44	chronic	chronic	ADJ
ajst-27318	81	45	inflammatory	inflammatory	ADJ
ajst-27318	81	46	response	response	NOUN
ajst-27318	81	47	.	.	PUNCT
ajst-27318	82	1	obese	obese	ADJ
ajst-27318	82	2	knee	knee	NOUN
ajst-27318	82	3	oa	oa	PROPN
ajst-27318	82	4	is	be	AUX
ajst-27318	82	5	closely	closely	ADV
ajst-27318	82	6	related	relate	VERB
ajst-27318	82	7	to	to	ADP
ajst-27318	82	8	inflammation	inflammation	NOUN
ajst-27318	82	9	and	and	CCONJ
ajst-27318	82	10	oxidative	oxidative	ADJ
ajst-27318	82	11	stress	stress	NOUN
ajst-27318	82	12	,	,	PUNCT
ajst-27318	82	13	which	which	PRON
ajst-27318	82	14	is	be	AUX
ajst-27318	82	15	an	an	DET
ajst-27318	82	16	important	important	ADJ
ajst-27318	82	17	factor	factor	NOUN
ajst-27318	82	18	involved	involve	VERB
ajst-27318	82	19	in	in	ADP
ajst-27318	82	20	cartilage	cartilage	NOUN
ajst-27318	82	21	degradation	degradation	NOUN
ajst-27318	82	22	leading	lead	VERB
ajst-27318	82	23	to	to	ADP
ajst-27318	82	24	cartilage	cartilage	NOUN
ajst-27318	82	25	degeneration	degeneration	NOUN
ajst-27318	82	26	.	.	PUNCT
ajst-27318	83	1	inflammatory	inflammatory	ADJ
ajst-27318	83	2	cytokines	cytokine	NOUN
ajst-27318	83	3	such	such	ADJ
ajst-27318	83	4	as	as	ADP
ajst-27318	83	5	il-1β	il-1β	PROPN
ajst-27318	83	6	and	and	CCONJ
ajst-27318	83	7	tnf	tnf	PROPN
ajst-27318	83	8	-	-	PUNCT
ajst-27318	83	9	α	α	PROPN
ajst-27318	83	10	mainly	mainly	ADV
ajst-27318	83	11	stimulate	stimulate	VERB
ajst-27318	83	12	the	the	DET
ajst-27318	83	13	production	production	NOUN
ajst-27318	83	14	of	of	ADP
ajst-27318	83	15	special	special	ADJ
ajst-27318	83	16	matrix	matrix	NOUN
ajst-27318	83	17	metalloproteinases	metalloproteinase	NOUN
ajst-27318	83	18	(	(	PUNCT
ajst-27318	83	19	mmps	mmp	NOUN
ajst-27318	83	20	)	)	PUNCT
ajst-27318	83	21	to	to	PART
ajst-27318	83	22	cause	cause	VERB
ajst-27318	83	23	the	the	DET
ajst-27318	83	24	degradation	degradation	NOUN
ajst-27318	83	25	of	of	ADP
ajst-27318	83	26	matrix	matrix	NOUN
ajst-27318	83	27	,	,	PUNCT
ajst-27318	83	28	and	and	CCONJ
ajst-27318	83	29	can	can	AUX
ajst-27318	83	30	induce	induce	VERB
ajst-27318	83	31	the	the	DET
ajst-27318	83	32	formation	formation	NOUN
ajst-27318	83	33	of	of	ADP
ajst-27318	83	34	inflammatory	inflammatory	ADJ
ajst-27318	83	35	mediators	mediator	NOUN
ajst-27318	83	36	by	by	ADP
ajst-27318	83	37	stimulating	stimulate	VERB
ajst-27318	83	38	the	the	DET
ajst-27318	83	39	proliferation	proliferation	NOUN
ajst-27318	83	40	and	and	CCONJ
ajst-27318	83	41	degeneration	degeneration	NOUN
ajst-27318	83	42	of	of	ADP
ajst-27318	83	43	synovial	synovial	ADJ
ajst-27318	83	44	cells	cell	NOUN
ajst-27318	83	45	.	.	PUNCT
ajst-27318	84	1	it	it	PRON
ajst-27318	84	2	can	can	AUX
ajst-27318	84	3	promote	promote	VERB
ajst-27318	84	4	the	the	DET
ajst-27318	84	5	secretion	secretion	NOUN
ajst-27318	84	6	of	of	ADP
ajst-27318	84	7	metalloproteinases	metalloproteinase	NOUN
ajst-27318	84	8	in	in	ADP
ajst-27318	84	9	synoviocytes	synoviocyte	NOUN
ajst-27318	84	10	,	,	PUNCT
ajst-27318	84	11	inhibit	inhibit	VERB
ajst-27318	84	12	or	or	CCONJ
ajst-27318	84	13	interfere	interfere	VERB
ajst-27318	84	14	with	with	ADP
ajst-27318	84	15	the	the	DET
ajst-27318	84	16	expression	expression	NOUN
ajst-27318	84	17	of	of	ADP
ajst-27318	84	18	chondrocytes	chondrocyte	NOUN
ajst-27318	84	19	and	and	CCONJ
ajst-27318	84	20	phenotypes	phenotype	NOUN
ajst-27318	84	21	.	.	PUNCT
ajst-27318	85	1	when	when	SCONJ
ajst-27318	85	2	the	the	DET
ajst-27318	85	3	duration	duration	NOUN
ajst-27318	85	4	of	of	ADP
ajst-27318	85	5	obesity	obesity	NOUN
ajst-27318	85	6	is	be	AUX
ajst-27318	85	7	longer	long	ADJ
ajst-27318	85	8	,	,	PUNCT
ajst-27318	85	9	the	the	DET
ajst-27318	85	10	antioxidant	antioxidant	ADJ
ajst-27318	85	11	sources	source	NOUN
ajst-27318	85	12	are	be	AUX
ajst-27318	85	13	reduced	reduce	VERB
ajst-27318	85	14	,	,	PUNCT
ajst-27318	85	15	resulting	result	VERB
ajst-27318	85	16	in	in	ADP
ajst-27318	85	17	decreased	decrease	VERB
ajst-27318	85	18	sod	sod	NOUN
ajst-27318	85	19	activity	activity	NOUN
ajst-27318	85	20	as	as	ADV
ajst-27318	85	21	well	well	ADV
ajst-27318	85	22	as	as	ADP
ajst-27318	85	23	increased	increase	VERB
ajst-27318	85	24	mda	mda	PROPN
ajst-27318	85	25	levels	level	NOUN
ajst-27318	85	26	.	.	PUNCT
ajst-27318	86	1	the	the	DET
ajst-27318	86	2	results	result	NOUN
ajst-27318	86	3	of	of	ADP
ajst-27318	86	4	the	the	DET
ajst-27318	86	5	present	present	ADJ
ajst-27318	86	6	study	study	NOUN
ajst-27318	86	7	showed	show	VERB
ajst-27318	86	8	that	that	SCONJ
ajst-27318	86	9	rap	rap	NOUN
ajst-27318	86	10	increased	increase	VERB
ajst-27318	86	11	sod	sod	NOUN
ajst-27318	86	12	activity	activity	NOUN
ajst-27318	86	13	and	and	CCONJ
ajst-27318	86	14	decreased	decrease	VERB
ajst-27318	86	15	mda	mda	PROPN
ajst-27318	86	16	levels	level	NOUN
ajst-27318	86	17	.	.	PUNCT
ajst-27318	87	1	it	it	PRON
ajst-27318	87	2	is	be	AUX
ajst-27318	87	3	suggested	suggest	VERB
ajst-27318	87	4	that	that	SCONJ
ajst-27318	87	5	rap	rap	NOUN
ajst-27318	87	6	can	can	AUX
ajst-27318	87	7	regulate	regulate	VERB
ajst-27318	87	8	serum	serum	VERB
ajst-27318	87	9	inflammatory	inflammatory	ADJ
ajst-27318	87	10	changes	change	NOUN
ajst-27318	87	11	and	and	CCONJ
ajst-27318	87	12	oxidative	oxidative	ADJ
ajst-27318	87	13	stress	stress	NOUN
ajst-27318	87	14	injury	injury	NOUN
ajst-27318	87	15	in	in	ADP
ajst-27318	87	16	model	model	NOUN
ajst-27318	87	17	rats	rat	NOUN
ajst-27318	87	18	,	,	PUNCT
ajst-27318	87	19	thereby	thereby	ADV
ajst-27318	87	20	improving	improve	VERB
ajst-27318	87	21	the	the	DET
ajst-27318	87	22	symptoms	symptom	NOUN
ajst-27318	87	23	of	of	ADP
ajst-27318	87	24	obese	obese	NOUN
ajst-27318	87	25	oa	oa	INTJ
ajst-27318	87	26	.	.	PUNCT
ajst-27318	87	27	timp-1	timp-1	NUM
ajst-27318	87	28	and	and	CCONJ
ajst-27318	87	29	mmp-3	mmp-3	PRON
ajst-27318	87	30	are	be	AUX
ajst-27318	87	31	important	important	ADJ
ajst-27318	87	32	cytokines	cytokine	NOUN
ajst-27318	87	33	in	in	ADP
ajst-27318	87	34	the	the	DET
ajst-27318	87	35	pathogenesis	pathogenesis	NOUN
ajst-27318	87	36	of	of	ADP
ajst-27318	87	37	oa	oa	INTJ
ajst-27318	87	38	.	.	PUNCT
ajst-27318	88	1	in	in	ADP
ajst-27318	88	2	the	the	DET
ajst-27318	88	3	pathogenesis	pathogenesis	NOUN
ajst-27318	88	4	of	of	ADP
ajst-27318	88	5	oa	oa	NOUN
ajst-27318	88	6	,	,	PUNCT
ajst-27318	88	7	mmps	mmp	NOUN
ajst-27318	88	8	play	play	VERB
ajst-27318	88	9	a	a	DET
ajst-27318	88	10	decisive	decisive	ADJ
ajst-27318	88	11	role	role	NOUN
ajst-27318	88	12	in	in	ADP
ajst-27318	88	13	the	the	DET
ajst-27318	88	14	imbalance	imbalance	NOUN
ajst-27318	88	15	of	of	ADP
ajst-27318	88	16	synthesis	synthesis	NOUN
ajst-27318	88	17	and	and	CCONJ
ajst-27318	88	18	degradation	degradation	NOUN
ajst-27318	88	19	of	of	ADP
ajst-27318	88	20	articular	articular	ADJ
ajst-27318	88	21	cartilage	cartilage	NOUN
ajst-27318	88	22	extracellular	extracellular	ADJ
ajst-27318	88	23	matrix	matrix	NOUN
ajst-27318	88	24	,	,	PUNCT
ajst-27318	88	25	and	and	CCONJ
ajst-27318	88	26	mmp-3	mmp-3	NUM
ajst-27318	88	27	gene	gene	NOUN
ajst-27318	88	28	is	be	AUX
ajst-27318	88	29	highly	highly	ADV
ajst-27318	88	30	expressed	express	VERB
ajst-27318	88	31	in	in	ADP
ajst-27318	88	32	patients	patient	NOUN
ajst-27318	88	33	with	with	ADP
ajst-27318	88	34	knee	knee	NOUN
ajst-27318	88	35	oa	oa	INTJ
ajst-27318	88	36	.	.	PUNCT
ajst-27318	89	1	in	in	ADP
ajst-27318	89	2	this	this	DET
ajst-27318	89	3	study	study	NOUN
ajst-27318	89	4	,	,	PUNCT
ajst-27318	89	5	the	the	DET
ajst-27318	89	6	protein	protein	NOUN
ajst-27318	89	7	expression	expression	NOUN
ajst-27318	89	8	of	of	ADP
ajst-27318	89	9	cartilage	cartilage	NOUN
ajst-27318	89	10	tissue	tissue	NOUN
ajst-27318	89	11	was	be	AUX
ajst-27318	89	12	detected	detect	VERB
ajst-27318	89	13	,	,	PUNCT
ajst-27318	89	14	and	and	CCONJ
ajst-27318	89	15	it	it	PRON
ajst-27318	89	16	was	be	AUX
ajst-27318	89	17	found	find	VERB
ajst-27318	89	18	that	that	SCONJ
ajst-27318	89	19	compared	compare	VERB
ajst-27318	89	20	with	with	ADP
ajst-27318	89	21	the	the	DET
ajst-27318	89	22	model	model	NOUN
ajst-27318	89	23	group	group	NOUN
ajst-27318	89	24	,	,	PUNCT
ajst-27318	89	25	the	the	DET
ajst-27318	89	26	rap	rap	NOUN
ajst-27318	89	27	treated	treat	VERB
ajst-27318	89	28	group	group	NOUN
ajst-27318	89	29	had	have	VERB
ajst-27318	89	30	a	a	DET
ajst-27318	89	31	significant	significant	ADJ
ajst-27318	89	32	inhibitory	inhibitory	ADJ
ajst-27318	89	33	effect	effect	NOUN
ajst-27318	89	34	on	on	ADP
ajst-27318	89	35	the	the	DET
ajst-27318	89	36	overexpression	overexpression	NOUN
ajst-27318	89	37	of	of	ADP
ajst-27318	89	38	mmp-3	mmp-3	NUM
ajst-27318	89	39	and	and	CCONJ
ajst-27318	89	40	timp-1	timp-1	NUM
ajst-27318	89	41	protein	protein	NOUN
ajst-27318	89	42	in	in	ADP
ajst-27318	89	43	the	the	DET
ajst-27318	89	44	model	model	NOUN
ajst-27318	89	45	mice	mouse	NOUN
ajst-27318	89	46	.	.	PUNCT
ajst-27318	90	1	these	these	DET
ajst-27318	90	2	results	result	NOUN
ajst-27318	90	3	indicate	indicate	VERB
ajst-27318	90	4	that	that	DET
ajst-27318	90	5	rap	rap	NOUN
ajst-27318	90	6	can	can	AUX
ajst-27318	90	7	regulate	regulate	VERB
ajst-27318	90	8	the	the	DET
ajst-27318	90	9	activity	activity	NOUN
ajst-27318	90	10	of	of	ADP
ajst-27318	90	11	mmp-3	mmp-3	NUM
ajst-27318	90	12	and	and	CCONJ
ajst-27318	90	13	the	the	DET
ajst-27318	90	14	expression	expression	NOUN
ajst-27318	90	15	of	of	ADP
ajst-27318	90	16	timp-1	timp-1	NOUN
ajst-27318	90	17	synchronously	synchronously	ADV
ajst-27318	90	18	,	,	PUNCT
ajst-27318	90	19	maintain	maintain	VERB
ajst-27318	90	20	their	their	PRON
ajst-27318	90	21	intrinsic	intrinsic	ADJ
ajst-27318	90	22	balance	balance	NOUN
ajst-27318	90	23	,	,	PUNCT
ajst-27318	90	24	and	and	CCONJ
ajst-27318	90	25	promote	promote	VERB
ajst-27318	90	26	the	the	DET
ajst-27318	90	27	synthesis	synthesis	NOUN
ajst-27318	90	28	of	of	ADP
ajst-27318	90	29	knee	knee	NOUN
ajst-27318	90	30	articular	articular	ADJ
ajst-27318	90	31	cartilage	cartilage	NOUN
ajst-27318	90	32	in	in	ADP
ajst-27318	90	33	obese	obese	ADJ
ajst-27318	90	34	rats	rat	NOUN
ajst-27318	90	35	.	.	PUNCT
ajst-27318	91	1	in	in	ADP
ajst-27318	91	2	conclusion	conclusion	NOUN
ajst-27318	91	3	,	,	PUNCT
ajst-27318	91	4	achyrantha	achyrantha	PROPN
ajst-27318	91	5	bidentata	bidentata	NOUN
ajst-27318	91	6	polysaccharide	polysaccharide	NOUN
ajst-27318	91	7	has	have	VERB
ajst-27318	91	8	lipid	lipid	NOUN
ajst-27318	91	9	-	-	PUNCT
ajst-27318	91	10	lowering	lower	VERB
ajst-27318	91	11	,	,	PUNCT
ajst-27318	91	12	anti	anti	ADJ
ajst-27318	91	13	-	-	ADJ
ajst-27318	91	14	inflammatory	inflammatory	ADJ
ajst-27318	91	15	and	and	CCONJ
ajst-27318	91	16	anti	anti	ADJ
ajst-27318	91	17	-	-	ADJ
ajst-27318	91	18	oxidative	oxidative	ADJ
ajst-27318	91	19	effects	effect	NOUN
ajst-27318	91	20	on	on	ADP
ajst-27318	91	21	knee	knee	NOUN
ajst-27318	91	22	oa	oa	NOUN
ajst-27318	91	23	in	in	ADP
ajst-27318	91	24	obese	obese	ADJ
ajst-27318	91	25	rats	rat	NOUN
ajst-27318	91	26	,	,	PUNCT
ajst-27318	91	27	and	and	CCONJ
ajst-27318	91	28	it	it	PRON
ajst-27318	91	29	can	can	AUX
ajst-27318	91	30	improve	improve	VERB
ajst-27318	91	31	oa	oa	PRON
ajst-27318	91	32	induced	induce	VERB
ajst-27318	91	33	by	by	ADP
ajst-27318	91	34	obesity	obesity	NOUN
ajst-27318	91	35	and	and	CCONJ
ajst-27318	91	36	ligament	ligament	NOUN
ajst-27318	91	37	injury	injury	NOUN
ajst-27318	91	38	by	by	ADP
ajst-27318	91	39	regulating	regulate	VERB
ajst-27318	91	40	the	the	DET
ajst-27318	91	41	balance	balance	NOUN
ajst-27318	91	42	of	of	ADP
ajst-27318	91	43	mmp-3	mmp-3	NUM
ajst-27318	91	44	and	and	CCONJ
ajst-27318	91	45	timp-1	timp-1	NUM
ajst-27318	91	46	.	.	NOUN
ajst-27318	91	47	5	5	NUM
ajst-27318	91	48	.	.	PUNCT
ajst-27318	92	1	conflicts	conflict	NOUN
ajst-27318	92	2	of	of	ADP
ajst-27318	92	3	interest	interest	NOUN
ajst-27318	92	4	the	the	DET
ajst-27318	92	5	authors	author	NOUN
ajst-27318	92	6	declare	declare	VERB
ajst-27318	92	7	that	that	SCONJ
ajst-27318	92	8	they	they	PRON
ajst-27318	92	9	have	have	VERB
ajst-27318	92	10	no	no	DET
ajst-27318	92	11	conflict	conflict	NOUN
ajst-27318	92	12	of	of	ADP
ajst-27318	92	13	interest	interest	NOUN
ajst-27318	92	14	.	.	PUNCT
ajst-27318	93	1	references	reference	NOUN
ajst-27318	93	2	[	[	X
ajst-27318	93	3	1	1	NUM
ajst-27318	93	4	]	]	X
ajst-27318	93	5	arashi	arashi	PROPN
ajst-27318	93	6	shahid	shahid	PROPN
ajst-27318	93	7	,	,	PUNCT
ajst-27318	93	8	aricia	aricia	NOUN
ajst-27318	93	9	jieqi	jieqi	NOUN
ajst-27318	93	10	thirumaran	thirumaran	PROPN
ajst-27318	93	11	,	,	PUNCT
ajst-27318	93	12	robin	robin	PROPN
ajst-27318	93	13	christensen	christensen	PROPN
ajst-27318	93	14	,	,	PUNCT
ajst-27318	93	15	venkatesha	venkatesha	PROPN
ajst-27318	93	16	venkatesha	venkatesha	PROPN
ajst-27318	93	17	,	,	PUNCT
ajst-27318	93	18	marius	marius	PROPN
ajst-27318	93	19	henriksen	henriksen	PROPN
ajst-27318	93	20	,	,	PUNCT
ajst-27318	93	21	jocelyn	jocelyn	PROPN
ajst-27318	93	22	l.	l.	PROPN
ajst-27318	93	23	bowden	bowden	PROPN
ajst-27318	93	24	,	,	PUNCT
ajst-27318	93	25	david	david	PROPN
ajst-27318	93	26	j.	j.	PROPN
ajst-27318	93	27	hunter.(2024).expression	hunter.(2024).expression	PROPN
ajst-27318	93	28	of	of	ADP
ajst-27318	93	29	concern	concern	NOUN
ajst-27318	93	30	;	;	PUNCT
ajst-27318	93	31	comparison	comparison	NOUN
ajst-27318	93	32	of	of	ADP
ajst-27318	93	33	weight	weight	NOUN
ajst-27318	93	34	loss	loss	NOUN
ajst-27318	93	35	interventions	intervention	NOUN
ajst-27318	93	36	in	in	ADP
ajst-27318	93	37	overweight	overweight	ADJ
ajst-27318	93	38	and	and	CCONJ
ajst-27318	93	39	obese	obese	ADJ
ajst-27318	93	40	adults	adult	NOUN
ajst-27318	93	41	with	with	ADP
ajst-27318	93	42	knee	knee	NOUN
ajst-27318	93	43	osteoarthritis	osteoarthritis	NOUN
ajst-27318	93	44	:	:	PUNCT
ajst-27318	93	45	a	a	DET
ajst-27318	93	46	systematic	systematic	ADJ
ajst-27318	93	47	review	review	NOUN
ajst-27318	93	48	and	and	CCONJ
ajst-27318	93	49	network	network	NOUN
ajst-27318	93	50	metaanalysis	metaanalysis	NOUN
ajst-27318	93	51	of	of	ADP
ajst-27318	93	52	randomized	randomize	VERB
ajst-27318	93	53	trials.osteoarthritis	trials.osteoarthritis	NOUN
ajst-27318	93	54	and	and	CCONJ
ajst-27318	93	55	cartilage	cartilage	NOUN
ajst-27318	93	56	(	(	PUNCT
ajst-27318	93	57	11	11	NUM
ajst-27318	93	58	)	)	PUNCT
ajst-27318	93	59	,	,	PUNCT
ajst-27318	93	60	1513	1513	NUM
ajst-27318	93	61	-	-	SYM
ajst-27318	93	62	1513	1513	NUM
ajst-27318	93	63	.	.	PUNCT
ajst-27318	94	1	[	[	X
ajst-27318	94	2	2	2	NUM
ajst-27318	94	3	]	]	PUNCT
ajst-27318	94	4	shifan	shifan	PROPN
ajst-27318	94	5	zhao	zhao	PROPN
ajst-27318	94	6	,	,	PUNCT
ajst-27318	94	7	yijiong	yijiong	PROPN
ajst-27318	94	8	tao	tao	PROPN
ajst-27318	94	9	,	,	PUNCT
ajst-27318	94	10	linjie	linjie	PROPN
ajst-27318	94	11	huang	huang	PROPN
ajst-27318	94	12	,	,	PUNCT
ajst-27318	94	13	hualei	hualei	PROPN
ajst-27318	94	14	xue	xue	PROPN
ajst-27318	94	15	,	,	PUNCT
ajst-27318	94	16	rong	rong	PROPN
ajst-27318	94	17	chen	chen	PROPN
ajst-27318	94	18	,	,	PUNCT
ajst-27318	94	19	xiao	xiao	PROPN
ajst-27318	94	20	li.mi	li.mi	PROPN
ajst-27318	94	21	wang.(2024).effects	wang.(2024).effect	VERB
ajst-27318	94	22	of	of	ADP
ajst-27318	94	23	polysaccharide	polysaccharide	NOUN
ajst-27318	94	24	from	from	ADP
ajst-27318	94	25	pueraria	pueraria	NOUN
ajst-27318	94	26	lobata	lobata	NOUN
ajst-27318	94	27	on	on	ADP
ajst-27318	94	28	osteoarthritis	osteoarthritis	NOUN
ajst-27318	94	29	in	in	ADP
ajst-27318	94	30	rats.international	rats.international	ADJ
ajst-27318	94	31	journal	journal	NOUN
ajst-27318	94	32	of	of	ADP
ajst-27318	94	33	biological	biological	ADJ
ajst-27318	94	34	macromolecules(p3),134901	macromolecules(p3),134901	NOUN
ajst-27318	94	35	-	-	SYM
ajst-27318	94	36	134901	134901	NUM
ajst-27318	94	37	.	.	PUNCT
ajst-27318	95	1	[	[	X
ajst-27318	95	2	3	3	X
ajst-27318	95	3	]	]	X
ajst-27318	95	4	yanzhi	yanzhi	PROPN
ajst-27318	95	5	liu	liu	PROPN
ajst-27318	95	6	,	,	PUNCT
ajst-27318	95	7	rui	rui	PROPN
ajst-27318	95	8	lin	lin	PROPN
ajst-27318	95	9	,	,	PUNCT
ajst-27318	95	10	haiping	haipe	VERB
ajst-27318	95	11	fang	fang	PROPN
ajst-27318	95	12	,	,	PUNCT
ajst-27318	95	13	lixian	lixian	PROPN
ajst-27318	95	14	li	li	PROPN
ajst-27318	95	15	,	,	PUNCT
ajst-27318	95	16	min	min	PROPN
ajst-27318	95	17	zhang	zhang	PROPN
ajst-27318	95	18	,	,	PUNCT
ajst-27318	95	19	lujiao	lujiao	NOUN
ajst-27318	95	20	lu.liao	lu.liao	ADP
ajst-27318	95	21	cui.(2024).sargassum	cui.(2024).sargassum	VERB
ajst-27318	95	22	polysaccharide	polysaccharide	NOUN
ajst-27318	95	23	attenuates	attenuate	NOUN
ajst-27318	95	24	osteoarthritis	osteoarthritis	NOUN
ajst-27318	95	25	in	in	ADP
ajst-27318	95	26	rats	rat	NOUN
ajst-27318	95	27	and	and	CCONJ
ajst-27318	95	28	is	be	AUX
ajst-27318	95	29	associated	associate	VERB
ajst-27318	95	30	with	with	ADP
ajst-27318	95	31	the	the	DET
ajst-27318	95	32	up	up	NOUN
ajst-27318	95	33	-	-	PUNCT
ajst-27318	95	34	regulation	regulation	NOUN
ajst-27318	95	35	of	of	ADP
ajst-27318	95	36	the	the	DET
ajst-27318	95	37	itgβ1	itgβ1	NOUN
ajst-27318	95	38	-	-	PUNCT
ajst-27318	95	39	pi3k	pi3k	NOUN
ajst-27318	95	40	-	-	PUNCT
ajst-27318	95	41	akt	akt	NOUN
ajst-27318	95	42	signaling	signal	VERB
ajst-27318	95	43	pathway	pathway	NOUN
ajst-27318	95	44	.	.	PUNCT
ajst-27318	96	1	journal	journal	NOUN
ajst-27318	96	2	of	of	ADP
ajst-27318	96	3	orthopaedic	orthopaedic	ADJ
ajst-27318	96	4	translation176	translation176	PROPN
ajst-27318	96	5	-	-	PUNCT
ajst-27318	96	6	190	190	NUM
ajst-27318	96	7	.	.	PUNCT
ajst-27318	97	1	[	[	X
ajst-27318	97	2	4	4	NUM
ajst-27318	97	3	]	]	X
ajst-27318	97	4	amany	amany	NOUN
ajst-27318	97	5	abd	abd	PROPN
ajst-27318	97	6	elaal	elaal	PROPN
ajst-27318	97	7	aiad	aiad	PROPN
ajst-27318	97	8	,	,	PUNCT
ajst-27318	97	9	sahar	sahar	PROPN
ajst-27318	97	10	mohamed	mohamed	PROPN
ajst-27318	97	11	el	el	PROPN
ajst-27318	97	12	haggar	haggar	PROPN
ajst-27318	97	13	,	,	PUNCT
ajst-27318	97	14	amal	amal	PROPN
ajst-27318	97	15	mohamed	mohamed	PROPN
ajst-27318	97	16	el	el	PROPN
ajst-27318	97	17	barbary	barbary	PROPN
ajst-27318	97	18	,	,	PUNCT
ajst-27318	97	19	dalia	dalia	PROPN
ajst-27318	97	20	refat	refat	PROPN
ajst-27318	97	21	el	el	PROPN
ajst-27318	97	22	afify.(2024).metformin	afify.(2024).metformin	PROPN
ajst-27318	97	23	as	as	ADP
ajst-27318	97	24	adjuvant	adjuvant	ADJ
ajst-27318	97	25	therapy	therapy	NOUN
ajst-27318	97	26	in	in	ADP
ajst-27318	97	27	obese	obese	ADJ
ajst-27318	97	28	knee	knee	NOUN
ajst-27318	97	29	osteoarthritis	osteoarthritis	NOUN
ajst-27318	97	30	patients	patient	NOUN
ajst-27318	97	31	..	..	PUNCT
ajst-27318	97	32	inflammopharmacology(4),2349	inflammopharmacology(4),2349	PROPN
ajst-27318	97	33	-	-	PUNCT
ajst-27318	97	34	2359	2359	NUM
ajst-27318	97	35	.	.	PUNCT
ajst-27318	98	1	[	[	X
ajst-27318	98	2	5	5	NUM
ajst-27318	98	3	]	]	SYM
ajst-27318	98	4	dolatkhah	dolatkhah	ADJ
ajst-27318	98	5	neda	neda	PROPN
ajst-27318	98	6	,	,	PUNCT
ajst-27318	98	7	toopchizadeh	toopchizadeh	NOUN
ajst-27318	98	8	vahideh	vahideh	PROPN
ajst-27318	98	9	,	,	PUNCT
ajst-27318	98	10	barmaki	barmaki	PROPN
ajst-27318	98	11	sahel	sahel	PROPN
ajst-27318	98	12	,	,	PUNCT
ajst-27318	98	13	salekzamani	salekzamani	ADJ
ajst-27318	98	14	yagoub	yagoub	NOUN
ajst-27318	98	15	,	,	PUNCT
ajst-27318	98	16	najjari	najjari	PROPN
ajst-27318	98	17	afsaneh	afsaneh	PROPN
ajst-27318	98	18	,	,	PUNCT
ajst-27318	98	19	farshbaf	farshbaf	PROPN
ajst-27318	98	20	khalili	khalili	PROPN
ajst-27318	98	21	azizeh	azizeh	PROPN
ajst-27318	98	22	dolati	dolati	PROPN
ajst-27318	98	23	sanam.(2022).the	sanam.(2022).the	ADJ
ajst-27318	98	24	effect	effect	NOUN
ajst-27318	98	25	of	of	ADP
ajst-27318	98	26	an	an	DET
ajst-27318	98	27	antiinflammatory	antiinflammatory	NOUN
ajst-27318	98	28	in	in	ADP
ajst-27318	98	29	comparison	comparison	NOUN
ajst-27318	98	30	with	with	ADP
ajst-27318	98	31	a	a	DET
ajst-27318	98	32	low	low	ADJ
ajst-27318	98	33	caloric	caloric	NOUN
ajst-27318	98	34	diet	diet	NOUN
ajst-27318	98	35	on	on	ADP
ajst-27318	98	36	physical	physical	ADJ
ajst-27318	98	37	and	and	CCONJ
ajst-27318	98	38	mental	mental	ADJ
ajst-27318	98	39	health	health	NOUN
ajst-27318	98	40	in	in	ADP
ajst-27318	98	41	overweight	overweight	NOUN
ajst-27318	98	42	and	and	CCONJ
ajst-27318	98	43	obese	obese	ADJ
ajst-27318	98	44	women	woman	NOUN
ajst-27318	98	45	with	with	ADP
ajst-27318	98	46	knee	knee	NOUN
ajst-27318	98	47	osteoarthritis	osteoarthritis	NOUN
ajst-27318	98	48	:	:	PUNCT
ajst-27318	98	49	a	a	DET
ajst-27318	98	50	randomized	randomized	ADJ
ajst-27318	98	51	clinical	clinical	ADJ
ajst-27318	98	52	trial	trial	NOUN
ajst-27318	98	53	..	..	PUNCT
ajst-27318	98	54	european	european	ADJ
ajst-27318	98	55	journal	journal	NOUN
ajst-27318	98	56	of	of	ADP
ajst-27318	98	57	nutrition(2),659	nutrition(2),659	NOUN
ajst-27318	98	58	-	-	PUNCT
ajst-27318	98	59	672	672	NUM
ajst-27318	98	60	.	.	PUNCT
ajst-27318	99	1	[	[	X
ajst-27318	99	2	6	6	NUM
ajst-27318	99	3	]	]	X
ajst-27318	99	4	alanazi	alanazi	PROPN
ajst-27318	99	5	j	j	PROPN
ajst-27318	99	6	,	,	PUNCT
ajst-27318	99	7	unnisa	unnisa	VERB
ajst-27318	99	8	a	a	DET
ajst-27318	99	9	,	,	PUNCT
ajst-27318	99	10	patel	patel	NOUN
ajst-27318	99	11	r	r	PROPN
ajst-27318	99	12	d	d	PROPN
ajst-27318	99	13	,	,	PUNCT
ajst-27318	99	14	itumalla	itumalla	PROPN
ajst-27318	99	15	r	r	PROPN
ajst-27318	99	16	,	,	PUNCT
ajst-27318	99	17	alanazi	alanazi	NOUN
ajst-27318	99	18	m	m	PROPN
ajst-27318	99	19	,	,	PUNCT
ajst-27318	99	20	alharby	alharby	PROPN
ajst-27318	99	21	t	t	PROPN
ajst-27318	99	22	n	n	CCONJ
ajst-27318	99	23	,	,	PUNCT
ajst-27318	99	24	mohamed	mohame	VERB
ajst-27318	99	25	o	o	PROPN
ajst-27318	99	26	a.(2022).prevalence	a.(2022).prevalence	NOUN
ajst-27318	99	27	of	of	ADP
ajst-27318	99	28	cardiovascular	cardiovascular	ADJ
ajst-27318	99	29	disease	disease	NOUN
ajst-27318	99	30	and	and	CCONJ
ajst-27318	99	31	osteoarthritis	osteoarthritis	NOUN
ajst-27318	99	32	in	in	ADP
ajst-27318	99	33	obese	obese	ADJ
ajst-27318	99	34	population	population	NOUN
ajst-27318	99	35	of	of	ADP
ajst-27318	99	36	hail	hail	NOUN
ajst-27318	99	37	region	region	NOUN
ajst-27318	99	38	,	,	PUNCT
ajst-27318	99	39	saudi	saudi	PROPN
ajst-27318	99	40	arabia	arabia	PROPN
ajst-27318	99	41	..	..	PUNCT
ajst-27318	99	42	european	european	PROPN
ajst-27318	99	43	review	review	PROPN
ajst-27318	99	44	for	for	ADP
ajst-27318	99	45	medical	medical	ADJ
ajst-27318	99	46	and	and	CCONJ
ajst-27318	99	47	pharmacological	pharmacological	ADJ
ajst-27318	99	48	sciences(19),7161	sciences(19),7161	NOUN
ajst-27318	99	49	-	-	PUNCT
ajst-27318	99	50	7168	7168	NUM
ajst-27318	99	51	.	.	PUNCT
ajst-27318	100	1	[	[	X
ajst-27318	100	2	7	7	NUM
ajst-27318	100	3	]	]	PUNCT
ajst-27318	100	4	oo	oo	INTJ
ajst-27318	100	5	win	win	NOUN
ajst-27318	100	6	min	min	PROPN
ajst-27318	100	7	,	,	PUNCT
ajst-27318	100	8	mobasheri	mobasheri	PROPN
ajst-27318	100	9	ali	ali	PROPN
ajst-27318	100	10	,	,	PUNCT
ajst-27318	100	11	hunter	hunter	PROPN
ajst-27318	100	12	david	david	PROPN
ajst-27318	100	13	j.(2022).a	j.(2022).a	PROPN
ajst-27318	100	14	narrative	narrative	NOUN
ajst-27318	100	15	review	review	NOUN
ajst-27318	100	16	of	of	ADP
ajst-27318	100	17	anti	anti	ADJ
ajst-27318	100	18	-	-	ADJ
ajst-27318	100	19	obesity	obesity	ADJ
ajst-27318	100	20	medications	medication	NOUN
ajst-27318	100	21	for	for	ADP
ajst-27318	100	22	obese	obese	ADJ
ajst-27318	100	23	patients	patient	NOUN
ajst-27318	100	24	with	with	ADP
ajst-27318	100	25	osteoarthritis	osteoarthritis	NOUN
ajst-27318	100	26	..	..	SYM
ajst-27318	100	27	expert	expert	ADJ
ajst-27318	100	28	opinion	opinion	NOUN
ajst-27318	100	29	on	on	ADP
ajst-27318	100	30	pharmacotherapy	pharmacotherapy	NOUN
ajst-27318	100	31	(	(	PUNCT
ajst-27318	100	32	12	12	NUM
ajst-27318	100	33	)	)	PUNCT
ajst-27318	100	34	,	,	PUNCT
ajst-27318	100	35	1381	1381	NUM
ajst-27318	100	36	-	-	SYM
ajst-27318	100	37	1395	1395	NUM
ajst-27318	100	38	.	.	PUNCT
ajst-27318	101	1	77	77	NUM
ajst-27318	102	1	[	[	NOUN
ajst-27318	102	2	8	8	X
ajst-27318	102	3	]	]	SYM
ajst-27318	102	4	obiegbu	obiegbu	ADJ
ajst-27318	102	5	obinna.(2022).osteoarthritis	obinna.(2022).osteoarthritis	NOUN
ajst-27318	102	6	of	of	ADP
ajst-27318	102	7	the	the	DET
ajst-27318	102	8	knee	knee	NOUN
ajst-27318	102	9	joint	joint	NOUN
ajst-27318	102	10	in	in	ADP
ajst-27318	102	11	the	the	DET
ajst-27318	102	12	obese	obese	ADJ
ajst-27318	102	13	patient	patient	NOUN
ajst-27318	102	14	:	:	PUNCT
ajst-27318	102	15	do	do	AUX
ajst-27318	102	16	metabolic	metabolic	NOUN
ajst-27318	102	17	factors	factor	NOUN
ajst-27318	102	18	play	play	VERB
ajst-27318	102	19	a	a	DET
ajst-27318	102	20	role?.sahel	role?.sahel	PROPN
ajst-27318	102	21	medical	medical	ADJ
ajst-27318	102	22	journal(2),57	journal(2),57	PROPN
ajst-27318	102	23	-	-	PUNCT
ajst-27318	102	24	60	60	NUM
ajst-27318	102	25	.	.	PUNCT
ajst-27318	103	1	[	[	X
ajst-27318	103	2	9	9	NUM
ajst-27318	103	3	]	]	SYM
ajst-27318	103	4	neslihan	neslihan	NOUN
ajst-27318	103	5	dülger	dülger	NOUN
ajst-27318	103	6	,	,	PUNCT
ajst-27318	103	7	mehmet	mehmet	PROPN
ajst-27318	103	8	akman	akman	PROPN
ajst-27318	103	9	,	,	PUNCT
ajst-27318	103	10	barış	barış	PROPN
ajst-27318	103	11	yilmaz	yilmaz	PROPN
ajst-27318	103	12	.	.	PUNCT
ajst-27318	104	1	(	(	PUNCT
ajst-27318	104	2	2022	2022	NUM
ajst-27318	104	3	)	)	PUNCT
ajst-27318	104	4	.	.	PUNCT
ajst-27318	105	1	the	the	DET
ajst-27318	105	2	effect	effect	NOUN
ajst-27318	105	3	of	of	ADP
ajst-27318	105	4	weight	weight	NOUN
ajst-27318	105	5	loss	loss	NOUN
ajst-27318	105	6	on	on	ADP
ajst-27318	105	7	osteoarthritis	osteoarthritis	NOUN
ajst-27318	105	8	symptoms	symptom	NOUN
ajst-27318	105	9	in	in	ADP
ajst-27318	105	10	obese	obese	ADJ
ajst-27318	105	11	patients	patient	NOUN
ajst-27318	105	12	with	with	ADP
ajst-27318	105	13	osteoarthritis.bezmialem	osteoarthritis.bezmialem	NUM
ajst-27318	105	14	science	science	NOUN
ajst-27318	105	15	(	(	PUNCT
ajst-27318	105	16	2	2	NUM
ajst-27318	105	17	)	)	PUNCT
ajst-27318	105	18	,	,	PUNCT
ajst-27318	105	19	206	206	NUM
ajst-27318	105	20	-	-	SYM
ajst-27318	105	21	211	211	NUM
ajst-27318	105	22	.	.	PUNCT
ajst-27318	106	1	[	[	X
ajst-27318	106	2	10	10	NUM
ajst-27318	106	3	]	]	PUNCT
ajst-27318	106	4	xu	xu	PROPN
ajst-27318	106	5	chao	chao	PROPN
ajst-27318	106	6	,	,	PUNCT
ajst-27318	106	7	ni	ni	PROPN
ajst-27318	106	8	su	su	PROPN
ajst-27318	106	9	,	,	PUNCT
ajst-27318	106	10	zhuang	zhuang	PROPN
ajst-27318	106	11	chao	chao	PROPN
ajst-27318	106	12	,	,	PUNCT
ajst-27318	106	13	li	li	PROPN
ajst-27318	106	14	chenkai	chenkai	PROPN
ajst-27318	106	15	,	,	PUNCT
ajst-27318	106	16	zhao	zhao	PROPN
ajst-27318	106	17	gongyin	gongyin	PROPN
ajst-27318	106	18	,	,	PUNCT
ajst-27318	106	19	jiang	jiang	PROPN
ajst-27318	106	20	shijie	shijie	PROPN
ajst-27318	106	21	,	,	PUNCT
ajst-27318	106	22	wang	wang	PROPN
ajst-27318	106	23	yuji.(2021).polysaccharide	yuji.(2021).polysaccharide	PROPN
ajst-27318	106	24	from	from	ADP
ajst-27318	106	25	angelica	angelica	PROPN
ajst-27318	106	26	sinensis	sinensis	NOUN
ajst-27318	106	27	attenuates	attenuate	VERB
ajst-27318	106	28	snp	snp	ADJ
ajst-27318	106	29	-	-	ADJ
ajst-27318	106	30	induced	induced	ADJ
ajst-27318	106	31	apoptosis	apoptosis	NOUN
ajst-27318	106	32	in	in	ADP
ajst-27318	106	33	osteoarthritis	osteoarthritis	NOUN
ajst-27318	106	34	chondrocytes	chondrocyte	NOUN
ajst-27318	106	35	by	by	ADP
ajst-27318	106	36	inducing	induce	VERB
ajst-27318	106	37	autophagy	autophagy	NOUN
ajst-27318	106	38	via	via	ADP
ajst-27318	106	39	the	the	DET
ajst-27318	106	40	erk1/2	erk1/2	PROPN
ajst-27318	106	41	pathway.arthritis	pathway.arthritis	PROPN
ajst-27318	106	42	research	research	NOUN
ajst-27318	106	43	&	&	CCONJ
ajst-27318	106	44	therapy(1),47	therapy(1),47	NOUN
ajst-27318	106	45	-	-	NUM
ajst-27318	106	46	47	47	NUM
ajst-27318	106	47	.	.	PUNCT
ajst-27318	107	1	[	[	X
ajst-27318	107	2	11	11	NUM
ajst-27318	107	3	]	]	PUNCT
ajst-27318	107	4	castro	castro	PROPN
ajst-27318	107	5	rondinelle	rondinelle	PROPN
ajst-27318	107	6	ribeiro	ribeiro	PROPN
ajst-27318	107	7	,	,	PUNCT
ajst-27318	107	8	feitosa	feitosa	PROPN
ajst-27318	107	9	judith	judith	PROPN
ajst-27318	107	10	pessoa	pessoa	PROPN
ajst-27318	107	11	andrade	andrade	PROPN
ajst-27318	107	12	,	,	PUNCT
ajst-27318	107	13	da	da	PROPN
ajst-27318	107	14	cunha	cunha	VERB
ajst-27318	107	15	pablyana	pablyana	PROPN
ajst-27318	107	16	leila	leila	PROPN
ajst-27318	107	17	rodrigues	rodrigues	PROPN
ajst-27318	107	18	,	,	PUNCT
ajst-27318	107	19	da	da	PROPN
ajst-27318	107	20	rocha	rocha	PROPN
ajst-27318	107	21	francisco	francisco	PROPN
ajst-27318	107	22	airton	airton	PROPN
ajst-27318	107	23	castro.(2007).analgesic	castro.(2007).analgesic	ADJ
ajst-27318	107	24	activity	activity	NOUN
ajst-27318	107	25	of	of	ADP
ajst-27318	107	26	a	a	DET
ajst-27318	107	27	polysaccharide	polysaccharide	NOUN
ajst-27318	107	28	in	in	ADP
ajst-27318	107	29	experimental	experimental	ADJ
ajst-27318	107	30	osteoarthritis	osteoarthritis	NOUN
ajst-27318	107	31	in	in	ADP
ajst-27318	107	32	rats	rat	NOUN
ajst-27318	107	33	..	..	PUNCT
ajst-27318	107	34	clinical	clinical	ADJ
ajst-27318	107	35	rheumatology	rheumatology	NOUN
ajst-27318	107	36	(	(	PUNCT
ajst-27318	107	37	8)	8)	NUM
ajst-27318	107	38	,	,	PUNCT
ajst-27318	107	39	1312	1312	NUM
ajst-27318	107	40	-	-	SYM
ajst-27318	107	41	9	9	NUM
ajst-27318	107	42	.	.	PUNCT
ajst-27318	108	1	[	[	X
ajst-27318	108	2	12	12	NUM
ajst-27318	108	3	]	]	PUNCT
ajst-27318	108	4	yanan	yanan	PROPN
ajst-27318	108	5	gao	gao	PROPN
ajst-27318	108	6	,	,	PUNCT
ajst-27318	108	7	mingkun	mingkun	PROPN
ajst-27318	108	8	guo	guo	PROPN
ajst-27318	108	9	,	,	PUNCT
ajst-27318	108	10	jiaqi	jiaqi	PROPN
ajst-27318	108	11	chen	chen	PROPN
ajst-27318	108	12	,	,	PUNCT
ajst-27318	108	13	yue	yue	PROPN
ajst-27318	108	14	sun	sun	PROPN
ajst-27318	108	15	,	,	PUNCT
ajst-27318	108	16	mingxing	mingxe	VERB
ajst-27318	108	17	wang	wang	PROPN
ajst-27318	108	18	.	.	PUNCT
ajst-27318	109	1	(	(	PUNCT
ajst-27318	109	2	2024	2024	NUM
ajst-27318	109	3	)	)	PUNCT
ajst-27318	109	4	.	.	PUNCT
ajst-27318	110	1	a	a	DET
ajst-27318	110	2	ginseng	ginseng	NOUN
ajst-27318	110	3	polysaccharide	polysaccharide	NOUN
ajst-27318	110	4	protects	protect	VERB
ajst-27318	110	5	intestinal	intestinal	ADJ
ajst-27318	110	6	barrier	barrier	NOUN
ajst-27318	110	7	integrity	integrity	NOUN
ajst-27318	110	8	in	in	ADP
ajst-27318	110	9	high	high	ADJ
ajst-27318	110	10	-	-	PUNCT
ajst-27318	110	11	fat	fat	NOUN
ajst-27318	110	12	diet	diet	NOUN
ajst-27318	110	13	-	-	PUNCT
ajst-27318	110	14	fed	feed	VERB
ajst-27318	110	15	obese	obese	ADJ
ajst-27318	110	16	mice	mouse	NOUN
ajst-27318	110	17	..	..	PUNCT
ajst-27318	110	18	international	international	ADJ
ajst-27318	110	19	journal	journal	NOUN
ajst-27318	110	20	of	of	ADP
ajst-27318	110	21	biological	biological	ADJ
ajst-27318	110	22	macromolecules	macromolecule	NOUN
ajst-27318	110	23	(	(	PUNCT
ajst-27318	110	24	p1	p1	NOUN
ajst-27318	110	25	)	)	PUNCT
ajst-27318	110	26	,	,	PUNCT
ajst-27318	110	27	133976	133976	NUM
ajst-27318	110	28	.	.	PUNCT