id	sid	tid	token	lemma	pos
ajst-32245	1	1	24	24	NUM
ajst-32245	1	2	biosensors	biosensor	NOUN
ajst-32245	1	3	in	in	ADP
ajst-32245	1	4	alzheimer	alzheimer	PROPN
ajst-32245	1	5	’s	’s	PART
ajst-32245	1	6	disease	disease	NOUN
ajst-32245	1	7	:	:	PUNCT
ajst-32245	1	8	emerging	emerge	VERB
ajst-32245	1	9	tools	tool	NOUN
ajst-32245	1	10	for	for	ADP
ajst-32245	1	11	early	early	ADJ
ajst-32245	1	12	diagnosis	diagnosis	NOUN
ajst-32245	1	13	zhixuan	zhixuan	PROPN
ajst-32245	1	14	li	li	PROPN
ajst-32245	1	15	college	college	PROPN
ajst-32245	1	16	of	of	ADP
ajst-32245	1	17	life	life	NOUN
ajst-32245	1	18	science	science	NOUN
ajst-32245	1	19	and	and	CCONJ
ajst-32245	1	20	technology	technology	NOUN
ajst-32245	1	21	,	,	PUNCT
ajst-32245	1	22	huazhong	huazhong	PROPN
ajst-32245	1	23	university	university	PROPN
ajst-32245	1	24	of	of	ADP
ajst-32245	1	25	science	science	NOUN
ajst-32245	1	26	and	and	CCONJ
ajst-32245	1	27	technology	technology	NOUN
ajst-32245	1	28	,	,	PUNCT
ajst-32245	1	29	wuhan	wuhan	PROPN
ajst-32245	1	30	,	,	PUNCT
ajst-32245	1	31	hubei	hubei	PROPN
ajst-32245	1	32	,	,	PUNCT
ajst-32245	1	33	china	china	PROPN
ajst-32245	1	34	zhixuanli@hust.edu.cn	zhixuanli@hust.edu.cn	PROPN
ajst-32245	1	35	abstract	abstract	NOUN
ajst-32245	1	36	.	.	PUNCT
ajst-32245	2	1	alzheimer	alzheimer	PROPN
ajst-32245	2	2	’s	’s	PART
ajst-32245	2	3	disease	disease	NOUN
ajst-32245	2	4	(	(	PUNCT
ajst-32245	2	5	ad	ad	NOUN
ajst-32245	2	6	)	)	PUNCT
ajst-32245	2	7	,	,	PUNCT
ajst-32245	2	8	a	a	DET
ajst-32245	2	9	prevalent	prevalent	ADJ
ajst-32245	2	10	neurodegenerative	neurodegenerative	ADJ
ajst-32245	2	11	disorder	disorder	NOUN
ajst-32245	2	12	,	,	PUNCT
ajst-32245	2	13	has	have	AUX
ajst-32245	2	14	experienced	experience	VERB
ajst-32245	2	15	a	a	DET
ajst-32245	2	16	marked	mark	VERB
ajst-32245	2	17	increase	increase	NOUN
ajst-32245	2	18	in	in	ADP
ajst-32245	2	19	incidence	incidence	NOUN
ajst-32245	2	20	due	due	ADJ
ajst-32245	2	21	to	to	ADP
ajst-32245	2	22	global	global	ADJ
ajst-32245	2	23	population	population	NOUN
ajst-32245	2	24	aging	aging	NOUN
ajst-32245	2	25	,	,	PUNCT
ajst-32245	2	26	imposing	impose	VERB
ajst-32245	2	27	substantial	substantial	ADJ
ajst-32245	2	28	challenges	challenge	NOUN
ajst-32245	2	29	on	on	ADP
ajst-32245	2	30	healthcare	healthcare	NOUN
ajst-32245	2	31	systems	system	NOUN
ajst-32245	2	32	.	.	PUNCT
ajst-32245	3	1	conventional	conventional	ADJ
ajst-32245	3	2	diagnostic	diagnostic	ADJ
ajst-32245	3	3	approaches	approach	NOUN
ajst-32245	3	4	are	be	AUX
ajst-32245	3	5	typically	typically	ADV
ajst-32245	3	6	applied	apply	VERB
ajst-32245	3	7	only	only	ADV
ajst-32245	3	8	after	after	ADP
ajst-32245	3	9	the	the	DET
ajst-32245	3	10	onset	onset	NOUN
ajst-32245	3	11	of	of	ADP
ajst-32245	3	12	overt	overt	ADJ
ajst-32245	3	13	cognitive	cognitive	ADJ
ajst-32245	3	14	impairment	impairment	NOUN
ajst-32245	3	15	.	.	PUNCT
ajst-32245	4	1	they	they	PRON
ajst-32245	4	2	are	be	AUX
ajst-32245	4	3	often	often	ADV
ajst-32245	4	4	constrained	constrain	VERB
ajst-32245	4	5	by	by	ADP
ajst-32245	4	6	operational	operational	ADJ
ajst-32245	4	7	complexity	complexity	NOUN
ajst-32245	4	8	,	,	PUNCT
ajst-32245	4	9	high	high	ADJ
ajst-32245	4	10	cost	cost	NOUN
ajst-32245	4	11	,	,	PUNCT
ajst-32245	4	12	and	and	CCONJ
ajst-32245	4	13	invasiveness	invasiveness	ADJ
ajst-32245	4	14	,	,	PUNCT
ajst-32245	4	15	limiting	limit	VERB
ajst-32245	4	16	their	their	PRON
ajst-32245	4	17	utility	utility	NOUN
ajst-32245	4	18	for	for	ADP
ajst-32245	4	19	early	early	ADJ
ajst-32245	4	20	detection	detection	NOUN
ajst-32245	4	21	.	.	PUNCT
ajst-32245	5	1	in	in	ADP
ajst-32245	5	2	recent	recent	ADJ
ajst-32245	5	3	years	year	NOUN
ajst-32245	5	4	,	,	PUNCT
ajst-32245	5	5	biosensor	biosensor	NOUN
ajst-32245	5	6	technology	technology	NOUN
ajst-32245	5	7	has	have	AUX
ajst-32245	5	8	emerged	emerge	VERB
ajst-32245	5	9	as	as	ADP
ajst-32245	5	10	a	a	DET
ajst-32245	5	11	promising	promising	ADJ
ajst-32245	5	12	tool	tool	NOUN
ajst-32245	5	13	for	for	ADP
ajst-32245	5	14	the	the	DET
ajst-32245	5	15	early	early	ADJ
ajst-32245	5	16	,	,	PUNCT
ajst-32245	5	17	rapid	rapid	ADJ
ajst-32245	5	18	,	,	PUNCT
ajst-32245	5	19	and	and	CCONJ
ajst-32245	5	20	non	non	ADJ
ajst-32245	5	21	-	-	ADJ
ajst-32245	5	22	invasive	invasive	ADJ
ajst-32245	5	23	ad	ad	NOUN
ajst-32245	5	24	diagnosis	diagnosis	NOUN
ajst-32245	5	25	due	due	ADP
ajst-32245	5	26	to	to	ADP
ajst-32245	5	27	its	its	PRON
ajst-32245	5	28	high	high	ADJ
ajst-32245	5	29	sensitivity	sensitivity	NOUN
ajst-32245	5	30	.	.	PUNCT
ajst-32245	6	1	this	this	DET
ajst-32245	6	2	review	review	NOUN
ajst-32245	6	3	summarizes	summarize	VERB
ajst-32245	6	4	the	the	DET
ajst-32245	6	5	advances	advance	NOUN
ajst-32245	6	6	and	and	CCONJ
ajst-32245	6	7	applications	application	NOUN
ajst-32245	6	8	of	of	ADP
ajst-32245	6	9	biosensors	biosensor	NOUN
ajst-32245	6	10	in	in	ADP
ajst-32245	6	11	ad	ad	NOUN
ajst-32245	6	12	diagnosis	diagnosis	NOUN
ajst-32245	6	13	and	and	CCONJ
ajst-32245	6	14	patient	patient	NOUN
ajst-32245	6	15	care	care	NOUN
ajst-32245	6	16	from	from	ADP
ajst-32245	6	17	2020	2020	NUM
ajst-32245	6	18	to	to	ADP
ajst-32245	6	19	2025	2025	NUM
ajst-32245	6	20	,	,	PUNCT
ajst-32245	6	21	with	with	ADP
ajst-32245	6	22	a	a	DET
ajst-32245	6	23	particular	particular	ADJ
ajst-32245	6	24	focus	focus	NOUN
ajst-32245	6	25	on	on	ADP
ajst-32245	6	26	electrochemical	electrochemical	ADJ
ajst-32245	6	27	and	and	CCONJ
ajst-32245	6	28	optical	optical	ADJ
ajst-32245	6	29	biosensors	biosensor	NOUN
ajst-32245	6	30	for	for	ADP
ajst-32245	6	31	detecting	detect	VERB
ajst-32245	6	32	key	key	ADJ
ajst-32245	6	33	ad	ad	NOUN
ajst-32245	6	34	-	-	PUNCT
ajst-32245	6	35	related	relate	VERB
ajst-32245	6	36	biomarkers	biomarker	NOUN
ajst-32245	6	37	,	,	PUNCT
ajst-32245	6	38	including	include	VERB
ajst-32245	6	39	β	β	NOUN
ajst-32245	6	40	-	-	NOUN
ajst-32245	6	41	amyloid	amyloid	NOUN
ajst-32245	6	42	,	,	PUNCT
ajst-32245	6	43	tau	tau	PROPN
ajst-32245	6	44	,	,	PUNCT
ajst-32245	6	45	phosphorylated	phosphorylate	VERB
ajst-32245	6	46	tau	tau	NOUN
ajst-32245	6	47	,	,	PUNCT
ajst-32245	6	48	and	and	CCONJ
ajst-32245	6	49	exosomal	exosomal	ADJ
ajst-32245	6	50	mirna	mirna	PROPN
ajst-32245	6	51	.	.	PUNCT
ajst-32245	7	1	strategies	strategy	NOUN
ajst-32245	7	2	for	for	ADP
ajst-32245	7	3	multiplexed	multiplexed	ADJ
ajst-32245	7	4	biomarker	biomarker	NOUN
ajst-32245	7	5	detection	detection	NOUN
ajst-32245	7	6	to	to	PART
ajst-32245	7	7	enhance	enhance	VERB
ajst-32245	7	8	diagnostic	diagnostic	ADJ
ajst-32245	7	9	accuracy	accuracy	NOUN
ajst-32245	7	10	are	be	AUX
ajst-32245	7	11	also	also	ADV
ajst-32245	7	12	discussed	discuss	VERB
ajst-32245	7	13	.	.	PUNCT
ajst-32245	8	1	moreover	moreover	ADV
ajst-32245	8	2	,	,	PUNCT
ajst-32245	8	3	the	the	DET
ajst-32245	8	4	review	review	NOUN
ajst-32245	8	5	highlights	highlight	VERB
ajst-32245	8	6	the	the	DET
ajst-32245	8	7	use	use	NOUN
ajst-32245	8	8	of	of	ADP
ajst-32245	8	9	biosensors	biosensor	NOUN
ajst-32245	8	10	in	in	ADP
ajst-32245	8	11	daily	daily	ADJ
ajst-32245	8	12	patient	patient	ADJ
ajst-32245	8	13	management	management	NOUN
ajst-32245	8	14	,	,	PUNCT
ajst-32245	8	15	encompassing	encompass	VERB
ajst-32245	8	16	real	real	ADJ
ajst-32245	8	17	-	-	PUNCT
ajst-32245	8	18	time	time	NOUN
ajst-32245	8	19	health	health	NOUN
ajst-32245	8	20	monitoring	monitoring	NOUN
ajst-32245	8	21	,	,	PUNCT
ajst-32245	8	22	optimization	optimization	NOUN
ajst-32245	8	23	of	of	ADP
ajst-32245	8	24	pharmacotherapy	pharmacotherapy	NOUN
ajst-32245	8	25	,	,	PUNCT
ajst-32245	8	26	and	and	CCONJ
ajst-32245	8	27	behavioral	behavioral	ADJ
ajst-32245	8	28	interventions	intervention	NOUN
ajst-32245	8	29	.	.	PUNCT
ajst-32245	9	1	despite	despite	SCONJ
ajst-32245	9	2	existing	exist	VERB
ajst-32245	9	3	sensitivity	sensitivity	NOUN
ajst-32245	9	4	,	,	PUNCT
ajst-32245	9	5	specificity	specificity	NOUN
ajst-32245	9	6	,	,	PUNCT
ajst-32245	9	7	standardization	standardization	NOUN
ajst-32245	9	8	,	,	PUNCT
ajst-32245	9	9	and	and	CCONJ
ajst-32245	9	10	clinical	clinical	ADJ
ajst-32245	9	11	translation	translation	NOUN
ajst-32245	9	12	challenges	challenge	NOUN
ajst-32245	9	13	,	,	PUNCT
ajst-32245	9	14	biosensor	biosensor	NOUN
ajst-32245	9	15	technologies	technology	NOUN
ajst-32245	9	16	are	be	AUX
ajst-32245	9	17	progressively	progressively	ADV
ajst-32245	9	18	moving	move	VERB
ajst-32245	9	19	toward	toward	ADP
ajst-32245	9	20	multi	multi	ADJ
ajst-32245	9	21	-	-	ADJ
ajst-32245	9	22	modal	modal	ADJ
ajst-32245	9	23	sensing	sensing	NOUN
ajst-32245	9	24	,	,	PUNCT
ajst-32245	9	25	integration	integration	NOUN
ajst-32245	9	26	with	with	ADP
ajst-32245	9	27	artificial	artificial	ADJ
ajst-32245	9	28	intelligence	intelligence	NOUN
ajst-32245	9	29	,	,	PUNCT
ajst-32245	9	30	and	and	CCONJ
ajst-32245	9	31	combination	combination	NOUN
ajst-32245	9	32	with	with	ADP
ajst-32245	9	33	microfluidic	microfluidic	ADJ
ajst-32245	9	34	platforms	platform	NOUN
ajst-32245	9	35	.	.	PUNCT
ajst-32245	10	1	this	this	DET
ajst-32245	10	2	review	review	NOUN
ajst-32245	10	3	aims	aim	VERB
ajst-32245	10	4	to	to	PART
ajst-32245	10	5	provide	provide	VERB
ajst-32245	10	6	insights	insight	NOUN
ajst-32245	10	7	into	into	ADP
ajst-32245	10	8	the	the	DET
ajst-32245	10	9	early	early	ADJ
ajst-32245	10	10	diagnosis	diagnosis	NOUN
ajst-32245	10	11	and	and	CCONJ
ajst-32245	10	12	personalized	personalized	ADJ
ajst-32245	10	13	management	management	NOUN
ajst-32245	10	14	of	of	ADP
ajst-32245	10	15	ad	ad	NOUN
ajst-32245	10	16	and	and	CCONJ
ajst-32245	10	17	to	to	PART
ajst-32245	10	18	outline	outline	VERB
ajst-32245	10	19	prospective	prospective	ADJ
ajst-32245	10	20	directions	direction	NOUN
ajst-32245	10	21	for	for	ADP
ajst-32245	10	22	future	future	ADJ
ajst-32245	10	23	research	research	NOUN
ajst-32245	10	24	in	in	ADP
ajst-32245	10	25	this	this	DET
ajst-32245	10	26	field	field	NOUN
ajst-32245	10	27	.	.	PUNCT
ajst-32245	11	1	keywords	keyword	NOUN
ajst-32245	11	2	:	:	PUNCT
ajst-32245	11	3	alzheimer	alzheimer	PROPN
ajst-32245	11	4	’s	’s	PART
ajst-32245	11	5	disease	disease	NOUN
ajst-32245	11	6	;	;	PUNCT
ajst-32245	11	7	electrochemical	electrochemical	ADJ
ajst-32245	11	8	biosensor	biosensor	NOUN
ajst-32245	11	9	;	;	PUNCT
ajst-32245	11	10	nanomaterials	nanomaterial	NOUN
ajst-32245	11	11	.	.	PUNCT
ajst-32245	12	1	1	1	X
ajst-32245	12	2	.	.	X
ajst-32245	12	3	introduction	introduction	PROPN
ajst-32245	12	4	alzheimer	alzheimer	PROPN
ajst-32245	12	5	’s	’s	PART
ajst-32245	12	6	disease	disease	NOUN
ajst-32245	12	7	(	(	PUNCT
ajst-32245	12	8	ad	ad	NOUN
ajst-32245	12	9	)	)	PUNCT
ajst-32245	12	10	is	be	AUX
ajst-32245	12	11	one	one	NUM
ajst-32245	12	12	of	of	ADP
ajst-32245	12	13	the	the	DET
ajst-32245	12	14	most	most	ADV
ajst-32245	12	15	common	common	ADJ
ajst-32245	12	16	human	human	ADJ
ajst-32245	12	17	neurodegenerative	neurodegenerative	ADJ
ajst-32245	12	18	disorders	disorder	NOUN
ajst-32245	12	19	,	,	PUNCT
ajst-32245	12	20	clinically	clinically	ADV
ajst-32245	12	21	characterized	characterize	VERB
ajst-32245	12	22	by	by	ADP
ajst-32245	12	23	a	a	DET
ajst-32245	12	24	progressive	progressive	ADJ
ajst-32245	12	25	decline	decline	NOUN
ajst-32245	12	26	in	in	ADP
ajst-32245	12	27	multiple	multiple	ADJ
ajst-32245	12	28	cognitive	cognitive	ADJ
ajst-32245	12	29	domains	domain	NOUN
ajst-32245	12	30	,	,	PUNCT
ajst-32245	12	31	including	include	VERB
ajst-32245	12	32	memory	memory	NOUN
ajst-32245	12	33	,	,	PUNCT
ajst-32245	12	34	learning	learn	VERB
ajst-32245	12	35	ability	ability	NOUN
ajst-32245	12	36	,	,	PUNCT
ajst-32245	12	37	language	language	NOUN
ajst-32245	12	38	,	,	PUNCT
ajst-32245	12	39	and	and	CCONJ
ajst-32245	12	40	executive	executive	ADJ
ajst-32245	12	41	function	function	NOUN
ajst-32245	12	42	,	,	PUNCT
ajst-32245	12	43	ultimately	ultimately	ADV
ajst-32245	12	44	leading	lead	VERB
ajst-32245	12	45	to	to	ADP
ajst-32245	12	46	global	global	ADJ
ajst-32245	12	47	dementia	dementia	NOUN
ajst-32245	12	48	[	[	X
ajst-32245	12	49	1	1	NUM
ajst-32245	12	50	]	]	PUNCT
ajst-32245	12	51	.	.	PUNCT
ajst-32245	13	1	with	with	ADP
ajst-32245	13	2	the	the	DET
ajst-32245	13	3	intensifying	intensify	VERB
ajst-32245	13	4	global	global	ADJ
ajst-32245	13	5	population	population	NOUN
ajst-32245	13	6	aging	aging	NOUN
ajst-32245	13	7	,	,	PUNCT
ajst-32245	13	8	the	the	DET
ajst-32245	13	9	incidence	incidence	NOUN
ajst-32245	13	10	and	and	CCONJ
ajst-32245	13	11	burden	burden	NOUN
ajst-32245	13	12	of	of	ADP
ajst-32245	13	13	ad	ad	NOUN
ajst-32245	13	14	are	be	AUX
ajst-32245	13	15	increasing	increase	VERB
ajst-32245	13	16	significantly	significantly	ADV
ajst-32245	13	17	.	.	PUNCT
ajst-32245	14	1	epidemiological	epidemiological	ADJ
ajst-32245	14	2	statistics	statistic	NOUN
ajst-32245	14	3	indicate	indicate	VERB
ajst-32245	14	4	that	that	SCONJ
ajst-32245	14	5	approximately	approximately	ADV
ajst-32245	14	6	50	50	NUM
ajst-32245	14	7	million	million	NUM
ajst-32245	14	8	people	people	NOUN
ajst-32245	14	9	worldwide	worldwide	ADV
ajst-32245	14	10	are	be	AUX
ajst-32245	14	11	affected	affect	VERB
ajst-32245	14	12	by	by	ADP
ajst-32245	14	13	dementia	dementia	NOUN
ajst-32245	14	14	,	,	PUNCT
ajst-32245	14	15	of	of	ADP
ajst-32245	14	16	which	which	PRON
ajst-32245	14	17	more	more	ADJ
ajst-32245	14	18	than	than	ADP
ajst-32245	14	19	60–70	60–70	NUM
ajst-32245	14	20	%	%	NOUN
ajst-32245	14	21	of	of	ADP
ajst-32245	14	22	cases	case	NOUN
ajst-32245	14	23	are	be	AUX
ajst-32245	14	24	attributed	attribute	VERB
ajst-32245	14	25	to	to	ADP
ajst-32245	14	26	ad	ad	NOUN
ajst-32245	14	27	,	,	PUNCT
ajst-32245	14	28	and	and	CCONJ
ajst-32245	14	29	the	the	DET
ajst-32245	14	30	number	number	NOUN
ajst-32245	14	31	of	of	ADP
ajst-32245	14	32	patients	patient	NOUN
ajst-32245	14	33	is	be	AUX
ajst-32245	14	34	projected	project	VERB
ajst-32245	14	35	to	to	PART
ajst-32245	14	36	double	double	VERB
ajst-32245	14	37	or	or	CCONJ
ajst-32245	14	38	even	even	ADV
ajst-32245	14	39	triple	triple	ADJ
ajst-32245	14	40	by	by	ADP
ajst-32245	14	41	2050	2050	NUM
ajst-32245	14	42	,	,	PUNCT
ajst-32245	14	43	posing	pose	VERB
ajst-32245	14	44	a	a	DET
ajst-32245	14	45	substantial	substantial	ADJ
ajst-32245	14	46	challenge	challenge	NOUN
ajst-32245	14	47	to	to	ADP
ajst-32245	14	48	healthcare	healthcare	NOUN
ajst-32245	14	49	systems	system	NOUN
ajst-32245	14	50	and	and	CCONJ
ajst-32245	14	51	public	public	ADJ
ajst-32245	14	52	health	health	NOUN
ajst-32245	14	53	resources	resource	NOUN
ajst-32245	14	54	[	[	X
ajst-32245	14	55	2	2	NUM
ajst-32245	14	56	]	]	PUNCT
ajst-32245	14	57	.	.	PUNCT
ajst-32245	15	1	pathologically	pathologically	ADV
ajst-32245	15	2	,	,	PUNCT
ajst-32245	15	3	ad	ad	NOUN
ajst-32245	15	4	is	be	AUX
ajst-32245	15	5	primarily	primarily	ADV
ajst-32245	15	6	characterized	characterize	VERB
ajst-32245	15	7	by	by	ADP
ajst-32245	15	8	the	the	DET
ajst-32245	15	9	deposition	deposition	NOUN
ajst-32245	15	10	of	of	ADP
ajst-32245	15	11	β	β	NOUN
ajst-32245	15	12	-	-	NOUN
ajst-32245	15	13	amyloid	amyloid	NOUN
ajst-32245	15	14	(	(	PUNCT
ajst-32245	15	15	aβ	aβ	NOUN
ajst-32245	15	16	)	)	PUNCT
ajst-32245	15	17	plaques	plaque	NOUN
ajst-32245	15	18	,	,	PUNCT
ajst-32245	15	19	neurofibrillary	neurofibrillary	ADJ
ajst-32245	15	20	tangles	tangle	NOUN
ajst-32245	15	21	caused	cause	VERB
ajst-32245	15	22	by	by	ADP
ajst-32245	15	23	tau	tau	PROPN
ajst-32245	15	24	hyperphosphorylation	hyperphosphorylation	NOUN
ajst-32245	15	25	,	,	PUNCT
ajst-32245	15	26	synaptic	synaptic	ADJ
ajst-32245	15	27	structural	structural	ADJ
ajst-32245	15	28	and	and	CCONJ
ajst-32245	15	29	functional	functional	ADJ
ajst-32245	15	30	impairments	impairment	NOUN
ajst-32245	15	31	,	,	PUNCT
ajst-32245	15	32	and	and	CCONJ
ajst-32245	15	33	persistent	persistent	ADJ
ajst-32245	15	34	neuroinflammation	neuroinflammation	NOUN
ajst-32245	15	35	in	in	ADP
ajst-32245	15	36	the	the	DET
ajst-32245	15	37	central	central	ADJ
ajst-32245	15	38	nervous	nervous	ADJ
ajst-32245	15	39	system	system	NOUN
ajst-32245	16	1	[	[	X
ajst-32245	16	2	3	3	NUM
ajst-32245	16	3	]	]	PUNCT
ajst-32245	16	4	.	.	PUNCT
ajst-32245	17	1	current	current	ADJ
ajst-32245	17	2	studies	study	NOUN
ajst-32245	17	3	suggest	suggest	VERB
ajst-32245	17	4	that	that	SCONJ
ajst-32245	17	5	the	the	DET
ajst-32245	17	6	onset	onset	NOUN
ajst-32245	17	7	and	and	CCONJ
ajst-32245	17	8	progression	progression	NOUN
ajst-32245	17	9	of	of	ADP
ajst-32245	17	10	ad	ad	NOUN
ajst-32245	17	11	represent	represent	VERB
ajst-32245	17	12	a	a	DET
ajst-32245	17	13	complex	complex	ADJ
ajst-32245	17	14	,	,	PUNCT
ajst-32245	17	15	multi	multi	ADJ
ajst-32245	17	16	-	-	ADJ
ajst-32245	17	17	factorial	factorial	ADJ
ajst-32245	17	18	,	,	PUNCT
ajst-32245	17	19	and	and	CCONJ
ajst-32245	17	20	multi	multi	ADJ
ajst-32245	17	21	-	-	ADJ
ajst-32245	17	22	stage	stage	ADJ
ajst-32245	17	23	pathological	pathological	ADJ
ajst-32245	17	24	process	process	NOUN
ajst-32245	17	25	,	,	PUNCT
ajst-32245	17	26	influenced	influence	VERB
ajst-32245	17	27	not	not	PART
ajst-32245	17	28	only	only	ADV
ajst-32245	17	29	by	by	ADP
ajst-32245	17	30	genetic	genetic	ADJ
ajst-32245	17	31	susceptibility	susceptibility	NOUN
ajst-32245	17	32	but	but	CCONJ
ajst-32245	17	33	also	also	ADV
ajst-32245	17	34	by	by	ADP
ajst-32245	17	35	environmental	environmental	ADJ
ajst-32245	17	36	factors	factor	NOUN
ajst-32245	17	37	and	and	CCONJ
ajst-32245	17	38	lifestyle	lifestyle	NOUN
ajst-32245	17	39	[	[	X
ajst-32245	17	40	4	4	NUM
ajst-32245	17	41	]	]	PUNCT
ajst-32245	17	42	.	.	PUNCT
ajst-32245	18	1	early	early	ADJ
ajst-32245	18	2	diagnosis	diagnosis	NOUN
ajst-32245	18	3	of	of	ADP
ajst-32245	18	4	ad	ad	NOUN
ajst-32245	18	5	is	be	AUX
ajst-32245	18	6	crucial	crucial	ADJ
ajst-32245	18	7	for	for	ADP
ajst-32245	18	8	delaying	delay	VERB
ajst-32245	18	9	disease	disease	NOUN
ajst-32245	18	10	progression	progression	NOUN
ajst-32245	18	11	and	and	CCONJ
ajst-32245	18	12	optimizing	optimize	VERB
ajst-32245	18	13	intervention	intervention	NOUN
ajst-32245	18	14	strategies	strategy	NOUN
ajst-32245	18	15	.	.	PUNCT
ajst-32245	19	1	unfortunately	unfortunately	ADV
ajst-32245	19	2	,	,	PUNCT
ajst-32245	19	3	conventional	conventional	ADJ
ajst-32245	19	4	clinical	clinical	ADJ
ajst-32245	19	5	diagnostic	diagnostic	ADJ
ajst-32245	19	6	methods	method	NOUN
ajst-32245	19	7	are	be	AUX
ajst-32245	19	8	typically	typically	ADV
ajst-32245	19	9	applied	apply	VERB
ajst-32245	19	10	only	only	ADV
ajst-32245	19	11	after	after	SCONJ
ajst-32245	19	12	the	the	DET
ajst-32245	19	13	patient	patient	NOUN
ajst-32245	19	14	exhibits	exhibit	VERB
ajst-32245	19	15	noticeable	noticeable	ADJ
ajst-32245	19	16	cognitive	cognitive	ADJ
ajst-32245	19	17	deficits	deficit	NOUN
ajst-32245	19	18	or	or	CCONJ
ajst-32245	19	19	functional	functional	ADJ
ajst-32245	19	20	impairments	impairment	NOUN
ajst-32245	19	21	,	,	PUNCT
ajst-32245	19	22	making	make	VERB
ajst-32245	19	23	it	it	PRON
ajst-32245	19	24	challenging	challenging	ADJ
ajst-32245	19	25	to	to	PART
ajst-32245	19	26	capture	capture	VERB
ajst-32245	19	27	the	the	DET
ajst-32245	19	28	latent	latent	NOUN
ajst-32245	19	29	or	or	CCONJ
ajst-32245	19	30	early	early	ADJ
ajst-32245	19	31	stages	stage	NOUN
ajst-32245	19	32	of	of	ADP
ajst-32245	19	33	the	the	DET
ajst-32245	19	34	disease	disease	NOUN
ajst-32245	19	35	[	[	X
ajst-32245	19	36	5	5	NUM
ajst-32245	19	37	]	]	PUNCT
ajst-32245	19	38	.	.	PUNCT
ajst-32245	20	1	moreover	moreover	ADV
ajst-32245	20	2	,	,	PUNCT
ajst-32245	20	3	these	these	DET
ajst-32245	20	4	methods	method	NOUN
ajst-32245	20	5	often	often	ADV
ajst-32245	20	6	rely	rely	VERB
ajst-32245	20	7	on	on	ADP
ajst-32245	20	8	neuroimaging	neuroimage	VERB
ajst-32245	20	9	,	,	PUNCT
ajst-32245	20	10	cerebrospinal	cerebrospinal	ADJ
ajst-32245	20	11	fluid	fluid	NOUN
ajst-32245	20	12	(	(	PUNCT
ajst-32245	20	13	csf	csf	NOUN
ajst-32245	20	14	)	)	PUNCT
ajst-32245	20	15	analysis	analysis	NOUN
ajst-32245	20	16	,	,	PUNCT
ajst-32245	20	17	and	and	CCONJ
ajst-32245	20	18	neuropsychological	neuropsychological	ADJ
ajst-32245	20	19	assessments	assessment	NOUN
ajst-32245	20	20	.	.	PUNCT
ajst-32245	21	1	these	these	PRON
ajst-32245	21	2	are	be	AUX
ajst-32245	21	3	complex	complex	ADJ
ajst-32245	21	4	,	,	PUNCT
ajst-32245	21	5	costly	costly	ADJ
ajst-32245	21	6	,	,	PUNCT
ajst-32245	21	7	and	and	CCONJ
ajst-32245	21	8	time	time	NOUN
ajst-32245	21	9	-	-	PUNCT
ajst-32245	21	10	consuming	consume	VERB
ajst-32245	21	11	and	and	CCONJ
ajst-32245	21	12	involve	involve	VERB
ajst-32245	21	13	invasive	invasive	ADJ
ajst-32245	21	14	procedures	procedure	NOUN
ajst-32245	21	15	(	(	PUNCT
ajst-32245	21	16	e.g.	e.g.	ADV
ajst-32245	21	17	,	,	PUNCT
ajst-32245	21	18	lumbar	lumbar	NOUN
ajst-32245	21	19	puncture	puncture	NOUN
ajst-32245	21	20	)	)	PUNCT
ajst-32245	21	21	that	that	PRON
ajst-32245	21	22	may	may	AUX
ajst-32245	21	23	affect	affect	VERB
ajst-32245	21	24	patient	patient	ADJ
ajst-32245	21	25	compliance	compliance	NOUN
ajst-32245	21	26	.	.	PUNCT
ajst-32245	22	1	these	these	DET
ajst-32245	22	2	limitations	limitation	NOUN
ajst-32245	22	3	significantly	significantly	ADV
ajst-32245	22	4	constrain	constrain	VERB
ajst-32245	22	5	the	the	DET
ajst-32245	22	6	application	application	NOUN
ajst-32245	22	7	of	of	ADP
ajst-32245	22	8	traditional	traditional	ADJ
ajst-32245	22	9	methods	method	NOUN
ajst-32245	22	10	in	in	ADP
ajst-32245	22	11	large	large	ADJ
ajst-32245	22	12	-	-	PUNCT
ajst-32245	22	13	scale	scale	NOUN
ajst-32245	22	14	population	population	NOUN
ajst-32245	22	15	screening	screening	NOUN
ajst-32245	22	16	and	and	CCONJ
ajst-32245	22	17	early	early	ADJ
ajst-32245	22	18	clinical	clinical	ADJ
ajst-32245	22	19	diagnosis	diagnosis	NOUN
ajst-32245	22	20	.	.	PUNCT
ajst-32245	23	1	25	25	NUM
ajst-32245	23	2	in	in	ADP
ajst-32245	23	3	contrast	contrast	NOUN
ajst-32245	23	4	,	,	PUNCT
ajst-32245	23	5	the	the	DET
ajst-32245	23	6	rapidly	rapidly	ADV
ajst-32245	23	7	developing	develop	VERB
ajst-32245	23	8	field	field	NOUN
ajst-32245	23	9	of	of	ADP
ajst-32245	23	10	biosensor	biosensor	NOUN
ajst-32245	23	11	technology	technology	NOUN
ajst-32245	23	12	has	have	AUX
ajst-32245	23	13	shown	show	VERB
ajst-32245	23	14	great	great	ADJ
ajst-32245	23	15	potential	potential	NOUN
ajst-32245	23	16	for	for	ADP
ajst-32245	23	17	early	early	ADJ
ajst-32245	23	18	,	,	PUNCT
ajst-32245	23	19	rapid	rapid	ADJ
ajst-32245	23	20	,	,	PUNCT
ajst-32245	23	21	and	and	CCONJ
ajst-32245	23	22	non	non	ADJ
ajst-32245	23	23	-	-	ADJ
ajst-32245	23	24	invasive	invasive	ADJ
ajst-32245	23	25	or	or	CCONJ
ajst-32245	23	26	minimally	minimally	ADV
ajst-32245	23	27	invasive	invasive	ADJ
ajst-32245	23	28	diagnosis	diagnosis	NOUN
ajst-32245	23	29	through	through	ADP
ajst-32245	23	30	highly	highly	ADV
ajst-32245	23	31	sensitive	sensitive	ADJ
ajst-32245	23	32	detection	detection	NOUN
ajst-32245	23	33	of	of	ADP
ajst-32245	23	34	ad	ad	NOUN
ajst-32245	23	35	-	-	PUNCT
ajst-32245	23	36	related	relate	VERB
ajst-32245	23	37	specific	specific	ADJ
ajst-32245	23	38	biomarkers	biomarker	NOUN
ajst-32245	23	39	,	,	PUNCT
ajst-32245	23	40	such	such	ADJ
ajst-32245	23	41	as	as	ADP
ajst-32245	23	42	aβ	aβ	PROPN
ajst-32245	23	43	,	,	PUNCT
ajst-32245	23	44	tau	tau	PROPN
ajst-32245	23	45	,	,	PUNCT
ajst-32245	23	46	and	and	CCONJ
ajst-32245	23	47	phosphorylated	phosphorylate	VERB
ajst-32245	23	48	tau	tau	NOUN
ajst-32245	23	49	.	.	PUNCT
ajst-32245	24	1	beyond	beyond	ADP
ajst-32245	24	2	early	early	ADJ
ajst-32245	24	3	diagnosis	diagnosis	NOUN
ajst-32245	24	4	,	,	PUNCT
ajst-32245	24	5	biosensors	biosensor	NOUN
ajst-32245	24	6	also	also	ADV
ajst-32245	24	7	hold	hold	VERB
ajst-32245	24	8	promise	promise	NOUN
ajst-32245	24	9	in	in	ADP
ajst-32245	24	10	the	the	DET
ajst-32245	24	11	daily	daily	ADJ
ajst-32245	24	12	management	management	NOUN
ajst-32245	24	13	of	of	ADP
ajst-32245	24	14	ad	ad	NOUN
ajst-32245	24	15	patients	patient	NOUN
ajst-32245	24	16	,	,	PUNCT
ajst-32245	24	17	including	include	VERB
ajst-32245	24	18	real	real	ADJ
ajst-32245	24	19	-	-	PUNCT
ajst-32245	24	20	time	time	NOUN
ajst-32245	24	21	health	health	NOUN
ajst-32245	24	22	monitoring	monitoring	NOUN
ajst-32245	24	23	,	,	PUNCT
ajst-32245	24	24	optimization	optimization	NOUN
ajst-32245	24	25	of	of	ADP
ajst-32245	24	26	pharmacotherapy	pharmacotherapy	NOUN
ajst-32245	24	27	,	,	PUNCT
ajst-32245	24	28	and	and	CCONJ
ajst-32245	24	29	behavioral	behavioral	ADJ
ajst-32245	24	30	interventions	intervention	NOUN
ajst-32245	24	31	.	.	PUNCT
ajst-32245	25	1	this	this	DET
ajst-32245	25	2	review	review	NOUN
ajst-32245	25	3	focuses	focus	VERB
ajst-32245	25	4	on	on	ADP
ajst-32245	25	5	the	the	DET
ajst-32245	25	6	applications	application	NOUN
ajst-32245	25	7	and	and	CCONJ
ajst-32245	25	8	innovations	innovation	NOUN
ajst-32245	25	9	of	of	ADP
ajst-32245	25	10	biosensors	biosensor	NOUN
ajst-32245	25	11	in	in	ADP
ajst-32245	25	12	the	the	DET
ajst-32245	25	13	early	early	ADJ
ajst-32245	25	14	diagnosis	diagnosis	NOUN
ajst-32245	25	15	and	and	CCONJ
ajst-32245	25	16	daily	daily	ADJ
ajst-32245	25	17	care	care	NOUN
ajst-32245	25	18	of	of	ADP
ajst-32245	25	19	ad	ad	NOUN
ajst-32245	25	20	over	over	ADP
ajst-32245	25	21	the	the	DET
ajst-32245	25	22	past	past	ADJ
ajst-32245	25	23	five	five	NUM
ajst-32245	25	24	years	year	NOUN
ajst-32245	25	25	(	(	PUNCT
ajst-32245	25	26	2020–2025	2020–2025	NUM
ajst-32245	25	27	)	)	PUNCT
ajst-32245	25	28	.	.	PUNCT
ajst-32245	26	1	the	the	DET
ajst-32245	26	2	relevant	relevant	ADJ
ajst-32245	26	3	scientific	scientific	ADJ
ajst-32245	26	4	literature	literature	NOUN
ajst-32245	26	5	published	publish	VERB
ajst-32245	26	6	between	between	ADP
ajst-32245	26	7	2020	2020	NUM
ajst-32245	26	8	and	and	CCONJ
ajst-32245	26	9	2025	2025	NUM
ajst-32245	26	10	was	be	AUX
ajst-32245	26	11	retrieved	retrieve	VERB
ajst-32245	26	12	from	from	ADP
ajst-32245	26	13	the	the	DET
ajst-32245	26	14	sciencedirect	sciencedirect	PROPN
ajst-32245	26	15	,	,	PUNCT
ajst-32245	26	16	pubmed	pubmed	PROPN
ajst-32245	26	17	,	,	PUNCT
ajst-32245	26	18	and	and	CCONJ
ajst-32245	26	19	google	google	PROPN
ajst-32245	26	20	scholar	scholar	NOUN
ajst-32245	26	21	databases	database	NOUN
ajst-32245	26	22	using	use	VERB
ajst-32245	26	23	the	the	DET
ajst-32245	26	24	following	follow	VERB
ajst-32245	26	25	keywords	keyword	NOUN
ajst-32245	26	26	:	:	PUNCT
ajst-32245	26	27	biosensor	biosensor	NOUN
ajst-32245	26	28	,	,	PUNCT
ajst-32245	26	29	electrochemical	electrochemical	ADJ
ajst-32245	26	30	immunosensor	immunosensor	NOUN
ajst-32245	26	31	,	,	PUNCT
ajst-32245	26	32	optical	optical	ADJ
ajst-32245	26	33	biosensor	biosensor	NOUN
ajst-32245	26	34	,	,	PUNCT
ajst-32245	26	35	alzheimer	alzheimer	PROPN
ajst-32245	26	36	’s	’s	PART
ajst-32245	26	37	disease	disease	NOUN
ajst-32245	26	38	,	,	PUNCT
ajst-32245	26	39	amyloid	amyloid	NOUN
ajst-32245	26	40	beta	beta	NOUN
ajst-32245	26	41	,	,	PUNCT
ajst-32245	26	42	tau	tau	PROPN
ajst-32245	26	43	protein	protein	NOUN
ajst-32245	26	44	,	,	PUNCT
ajst-32245	26	45	apolipoprotein	apolipoprotein	ADJ
ajst-32245	26	46	e	e	NOUN
ajst-32245	26	47	,	,	PUNCT
ajst-32245	26	48	and	and	CCONJ
ajst-32245	26	49	behavior	behavior	NOUN
ajst-32245	26	50	detection	detection	NOUN
ajst-32245	26	51	.	.	PUNCT
ajst-32245	27	1	2	2	X
ajst-32245	27	2	.	.	X
ajst-32245	27	3	biosensors	biosensor	NOUN
ajst-32245	27	4	for	for	ADP
ajst-32245	27	5	alzheimer	alzheimer	PROPN
ajst-32245	27	6	’s	’s	PART
ajst-32245	27	7	disease	disease	NOUN
ajst-32245	27	8	diagnosis	diagnosis	NOUN
ajst-32245	27	9	biosensors	biosensor	NOUN
ajst-32245	27	10	,	,	PUNCT
ajst-32245	27	11	which	which	PRON
ajst-32245	27	12	are	be	AUX
ajst-32245	27	13	composed	compose	VERB
ajst-32245	27	14	of	of	ADP
ajst-32245	27	15	bioreceptors	bioreceptor	NOUN
ajst-32245	27	16	,	,	PUNCT
ajst-32245	27	17	transducers	transducer	NOUN
ajst-32245	27	18	,	,	PUNCT
ajst-32245	27	19	technologies	technology	NOUN
ajst-32245	27	20	,	,	PUNCT
ajst-32245	27	21	and	and	CCONJ
ajst-32245	27	22	detection	detection	NOUN
ajst-32245	27	23	systems	system	NOUN
ajst-32245	27	24	,	,	PUNCT
ajst-32245	27	25	can	can	AUX
ajst-32245	27	26	be	be	AUX
ajst-32245	27	27	classified	classify	VERB
ajst-32245	27	28	into	into	ADP
ajst-32245	27	29	various	various	ADJ
ajst-32245	27	30	types	type	NOUN
ajst-32245	27	31	[	[	X
ajst-32245	27	32	6	6	NUM
ajst-32245	27	33	]	]	PUNCT
ajst-32245	27	34	.	.	PUNCT
ajst-32245	28	1	this	this	DET
ajst-32245	28	2	review	review	NOUN
ajst-32245	28	3	primarily	primarily	ADV
ajst-32245	28	4	focuses	focus	VERB
ajst-32245	28	5	on	on	ADP
ajst-32245	28	6	electrochemical	electrochemical	ADJ
ajst-32245	28	7	biosensors	biosensor	NOUN
ajst-32245	28	8	,	,	PUNCT
ajst-32245	28	9	optical	optical	ADJ
ajst-32245	28	10	biosensors	biosensor	NOUN
ajst-32245	28	11	,	,	PUNCT
ajst-32245	28	12	and	and	CCONJ
ajst-32245	28	13	nanomaterial	nanomaterial	NOUN
ajst-32245	28	14	-	-	PUNCT
ajst-32245	28	15	enhanced	enhance	VERB
ajst-32245	28	16	sensors	sensor	NOUN
ajst-32245	28	17	to	to	PART
ajst-32245	28	18	recognize	recognize	VERB
ajst-32245	28	19	biomarkers	biomarker	NOUN
ajst-32245	28	20	and	and	CCONJ
ajst-32245	28	21	their	their	PRON
ajst-32245	28	22	diagnostic	diagnostic	ADJ
ajst-32245	28	23	performance	performance	NOUN
ajst-32245	28	24	.	.	PUNCT
ajst-32245	29	1	common	common	ADJ
ajst-32245	29	2	biomarkers	biomarker	NOUN
ajst-32245	29	3	to	to	PART
ajst-32245	29	4	diagnose	diagnose	VERB
ajst-32245	29	5	alzheimer	alzheimer	PROPN
ajst-32245	29	6	’s	’s	PART
ajst-32245	29	7	disease	disease	NOUN
ajst-32245	29	8	include	include	VERB
ajst-32245	29	9	β	β	X
ajst-32245	29	10	-	-	NOUN
ajst-32245	29	11	amyloid	amyloid	NOUN
ajst-32245	29	12	(	(	PUNCT
ajst-32245	29	13	aβ	aβ	NOUN
ajst-32245	29	14	)	)	PUNCT
ajst-32245	29	15	,	,	PUNCT
ajst-32245	29	16	tau	tau	PROPN
ajst-32245	29	17	protein	protein	NOUN
ajst-32245	29	18	,	,	PUNCT
ajst-32245	29	19	phosphorylated	phosphorylate	VERB
ajst-32245	29	20	tau	tau	PROPN
ajst-32245	29	21	protein	protein	NOUN
ajst-32245	29	22	(	(	PUNCT
ajst-32245	29	23	p	p	NOUN
ajst-32245	29	24	-	-	PUNCT
ajst-32245	29	25	tau	tau	NOUN
ajst-32245	29	26	)	)	PUNCT
ajst-32245	29	27	,	,	PUNCT
ajst-32245	29	28	and	and	CCONJ
ajst-32245	29	29	exosomal	exosomal	ADJ
ajst-32245	29	30	mirnas	mirna	NOUN
ajst-32245	29	31	.	.	PUNCT
ajst-32245	30	1	2.1	2.1	NUM
ajst-32245	30	2	biomarker	biomarker	NOUN
ajst-32245	30	3	recognition	recognition	NOUN
ajst-32245	30	4	by	by	ADP
ajst-32245	30	5	biosensors	biosensor	NOUN
ajst-32245	30	6	electrochemical	electrochemical	ADJ
ajst-32245	30	7	biosensors	biosensor	NOUN
ajst-32245	30	8	convert	convert	VERB
ajst-32245	30	9	biomolecular	biomolecular	ADJ
ajst-32245	30	10	recognition	recognition	NOUN
ajst-32245	30	11	events	event	NOUN
ajst-32245	30	12	into	into	ADP
ajst-32245	30	13	measurable	measurable	ADJ
ajst-32245	30	14	electrical	electrical	ADJ
ajst-32245	30	15	signals	signal	NOUN
ajst-32245	30	16	(	(	PUNCT
ajst-32245	30	17	current	current	ADJ
ajst-32245	30	18	,	,	PUNCT
ajst-32245	30	19	voltage	voltage	NOUN
ajst-32245	30	20	,	,	PUNCT
ajst-32245	30	21	or	or	CCONJ
ajst-32245	30	22	impedance	impedance	NOUN
ajst-32245	30	23	changes	change	NOUN
ajst-32245	30	24	)	)	PUNCT
ajst-32245	30	25	by	by	ADP
ajst-32245	30	26	integrating	integrate	VERB
ajst-32245	30	27	biorecognition	biorecognition	NOUN
ajst-32245	30	28	elements	element	NOUN
ajst-32245	30	29	such	such	ADJ
ajst-32245	30	30	as	as	ADP
ajst-32245	30	31	antibodies	antibody	NOUN
ajst-32245	30	32	,	,	PUNCT
ajst-32245	30	33	aptamers	aptamer	NOUN
ajst-32245	30	34	,	,	PUNCT
ajst-32245	30	35	enzymes	enzyme	NOUN
ajst-32245	30	36	,	,	PUNCT
ajst-32245	30	37	or	or	CCONJ
ajst-32245	30	38	single	single	ADV
ajst-32245	30	39	-	-	PUNCT
ajst-32245	30	40	stranded	strand	VERB
ajst-32245	30	41	dna	dna	NOUN
ajst-32245	30	42	with	with	ADP
ajst-32245	30	43	electrochemical	electrochemical	ADJ
ajst-32245	30	44	transducers	transducer	NOUN
ajst-32245	30	45	[	[	X
ajst-32245	30	46	7	7	NUM
ajst-32245	30	47	,	,	PUNCT
ajst-32245	30	48	8	8	NUM
ajst-32245	30	49	]	]	PUNCT
ajst-32245	30	50	.	.	PUNCT
ajst-32245	31	1	figure	figure	NOUN
ajst-32245	31	2	1	1	NUM
ajst-32245	31	3	.	.	PUNCT
ajst-32245	32	1	mechanism	mechanism	NOUN
ajst-32245	32	2	of	of	ADP
ajst-32245	32	3	electrochemical	electrochemical	ADJ
ajst-32245	32	4	biosensor	biosensor	NOUN
ajst-32245	32	5	the	the	DET
ajst-32245	32	6	schematic	schematic	ADJ
ajst-32245	32	7	above	above	ADV
ajst-32245	32	8	illustrates	illustrate	VERB
ajst-32245	32	9	the	the	DET
ajst-32245	32	10	basic	basic	ADJ
ajst-32245	32	11	working	working	NOUN
ajst-32245	32	12	principle	principle	NOUN
ajst-32245	32	13	of	of	ADP
ajst-32245	32	14	electrochemical	electrochemical	ADJ
ajst-32245	32	15	biosensors	biosensor	NOUN
ajst-32245	32	16	:	:	PUNCT
ajst-32245	32	17	target	target	NOUN
ajst-32245	32	18	analytes	analyte	NOUN
ajst-32245	32	19	are	be	AUX
ajst-32245	32	20	specifically	specifically	ADV
ajst-32245	32	21	recognized	recognize	VERB
ajst-32245	32	22	and	and	CCONJ
ajst-32245	32	23	bound	bind	VERB
ajst-32245	32	24	by	by	ADP
ajst-32245	32	25	receptors	receptor	NOUN
ajst-32245	32	26	,	,	PUNCT
ajst-32245	32	27	generating	generate	VERB
ajst-32245	32	28	signals	signal	NOUN
ajst-32245	32	29	that	that	PRON
ajst-32245	32	30	can	can	AUX
ajst-32245	32	31	be	be	AUX
ajst-32245	32	32	processed	process	VERB
ajst-32245	32	33	and	and	CCONJ
ajst-32245	32	34	quantified	quantify	VERB
ajst-32245	32	35	.	.	PUNCT
ajst-32245	33	1	in	in	ADP
ajst-32245	33	2	the	the	DET
ajst-32245	33	3	early	early	ADJ
ajst-32245	33	4	diagnosis	diagnosis	NOUN
ajst-32245	33	5	of	of	ADP
ajst-32245	33	6	alzheimer	alzheimer	PROPN
ajst-32245	33	7	’s	’s	PART
ajst-32245	33	8	disease	disease	NOUN
ajst-32245	33	9	(	(	PUNCT
ajst-32245	33	10	ad	ad	NOUN
ajst-32245	33	11	)	)	PUNCT
ajst-32245	33	12	,	,	PUNCT
ajst-32245	33	13	electrochemical	electrochemical	ADJ
ajst-32245	33	14	biosensors	biosensor	NOUN
ajst-32245	33	15	have	have	AUX
ajst-32245	33	16	been	be	AUX
ajst-32245	33	17	extensively	extensively	ADV
ajst-32245	33	18	studied	study	VERB
ajst-32245	33	19	for	for	ADP
ajst-32245	33	20	their	their	PRON
ajst-32245	33	21	capacity	capacity	NOUN
ajst-32245	33	22	to	to	PART
ajst-32245	33	23	detect	detect	VERB
ajst-32245	33	24	disease	disease	NOUN
ajst-32245	33	25	-	-	PUNCT
ajst-32245	33	26	related	relate	VERB
ajst-32245	33	27	biomarkers	biomarker	NOUN
ajst-32245	33	28	.	.	PUNCT
ajst-32245	34	1	among	among	ADP
ajst-32245	34	2	these	these	PRON
ajst-32245	34	3	,	,	PUNCT
ajst-32245	34	4	β	β	NOUN
ajst-32245	34	5	-	-	NOUN
ajst-32245	34	6	amyloid	amyloid	NOUN
ajst-32245	34	7	(	(	PUNCT
ajst-32245	34	8	aβ	aβ	NOUN
ajst-32245	34	9	)	)	PUNCT
ajst-32245	34	10	,	,	PUNCT
ajst-32245	34	11	particularly	particularly	ADV
ajst-32245	34	12	aβ42	aβ42	PROPN
ajst-32245	34	13	,	,	PUNCT
ajst-32245	34	14	is	be	AUX
ajst-32245	34	15	considered	consider	VERB
ajst-32245	34	16	a	a	DET
ajst-32245	34	17	critical	critical	ADJ
ajst-32245	34	18	biomarker	biomarker	NOUN
ajst-32245	34	19	,	,	PUNCT
ajst-32245	34	20	and	and	CCONJ
ajst-32245	34	21	numerous	numerous	ADJ
ajst-32245	34	22	studies	study	NOUN
ajst-32245	34	23	have	have	AUX
ajst-32245	34	24	focused	focus	VERB
ajst-32245	34	25	on	on	ADP
ajst-32245	34	26	developing	develop	VERB
ajst-32245	34	27	electrochemical	electrochemical	ADJ
ajst-32245	34	28	biosensors	biosensor	NOUN
ajst-32245	34	29	specifically	specifically	ADV
ajst-32245	34	30	targeting	target	VERB
ajst-32245	34	31	this	this	DET
ajst-32245	34	32	peptide	peptide	NOUN
ajst-32245	35	1	[	[	X
ajst-32245	35	2	9–11	9–11	NOUN
ajst-32245	35	3	]	]	PUNCT
ajst-32245	35	4	.	.	PUNCT
ajst-32245	36	1	for	for	ADP
ajst-32245	36	2	example	example	NOUN
ajst-32245	36	3	,	,	PUNCT
ajst-32245	36	4	a	a	DET
ajst-32245	36	5	cnt	cnt	X
ajst-32245	36	6	–	–	PUNCT
ajst-32245	36	7	metal	metal	NOUN
ajst-32245	36	8	–	–	PUNCT
ajst-32245	36	9	porous	porous	ADJ
ajst-32245	36	10	graphene	graphene	NOUN
ajst-32245	36	11	hybrid	hybrid	NOUN
ajst-32245	36	12	(	(	PUNCT
ajst-32245	36	13	cnt	cnt	PROPN
ajst-32245	36	14	-	-	PUNCT
ajst-32245	36	15	mgh	mgh	NOUN
ajst-32245	36	16	)	)	PUNCT
ajst-32245	36	17	nanofork	nanofork	NOUN
ajst-32245	36	18	array	array	NOUN
ajst-32245	36	19	(	(	PUNCT
ajst-32245	36	20	n	n	X
ajst-32245	36	21	-	-	PUNCT
ajst-32245	36	22	ida	ida	PROPN
ajst-32245	36	23	)	)	PUNCT
ajst-32245	36	24	biosensor	biosensor	NOUN
ajst-32245	36	25	has	have	AUX
ajst-32245	36	26	been	be	AUX
ajst-32245	36	27	designed	design	VERB
ajst-32245	36	28	for	for	ADP
ajst-32245	36	29	the	the	DET
ajst-32245	36	30	detection	detection	NOUN
ajst-32245	36	31	of	of	ADP
ajst-32245	36	32	aβ42	aβ42	PROPN
ajst-32245	36	33	in	in	ADP
ajst-32245	36	34	blood	blood	NOUN
ajst-32245	36	35	samples	sample	NOUN
ajst-32245	36	36	,	,	PUNCT
ajst-32245	36	37	thereby	thereby	ADV
ajst-32245	36	38	enabling	enable	VERB
ajst-32245	36	39	early	early	ADJ
ajst-32245	36	40	ad	ad	NOUN
ajst-32245	36	41	diagnosis	diagnosis	NOUN
ajst-32245	36	42	[	[	X
ajst-32245	36	43	12	12	NUM
ajst-32245	36	44	]	]	PUNCT
ajst-32245	36	45	.	.	PUNCT
ajst-32245	37	1	similarly	similarly	ADV
ajst-32245	37	2	,	,	PUNCT
ajst-32245	37	3	a	a	DET
ajst-32245	37	4	polyadenine	polyadenine	NOUN
ajst-32245	37	5	-	-	PUNCT
ajst-32245	37	6	assisted	assist	VERB
ajst-32245	37	7	signal	signal	NOUN
ajst-32245	37	8	displacement	displacement	NOUN
ajst-32245	37	9	aptamer	aptamer	NOUN
ajst-32245	37	10	biosensor	biosensor	NOUN
ajst-32245	37	11	has	have	AUX
ajst-32245	37	12	been	be	AUX
ajst-32245	37	13	employed	employ	VERB
ajst-32245	37	14	to	to	PART
ajst-32245	37	15	detect	detect	VERB
ajst-32245	37	16	aβ	aβ	DET
ajst-32245	37	17	biomarkers	biomarker	NOUN
ajst-32245	38	1	precisely	precisely	ADV
ajst-32245	38	2	[	[	X
ajst-32245	38	3	11	11	NUM
ajst-32245	38	4	]	]	PUNCT
ajst-32245	38	5	.	.	PUNCT
ajst-32245	39	1	beyond	beyond	ADP
ajst-32245	39	2	electrochemical	electrochemical	ADJ
ajst-32245	39	3	techniques	technique	NOUN
ajst-32245	39	4	,	,	PUNCT
ajst-32245	39	5	optical	optical	ADJ
ajst-32245	39	6	biosensors	biosensor	NOUN
ajst-32245	39	7	have	have	AUX
ajst-32245	39	8	also	also	ADV
ajst-32245	39	9	been	be	AUX
ajst-32245	39	10	developed	develop	VERB
ajst-32245	39	11	,	,	PUNCT
ajst-32245	39	12	such	such	ADJ
ajst-32245	39	13	as	as	ADP
ajst-32245	39	14	an	an	DET
ajst-32245	39	15	impedance	impedance	NOUN
ajst-32245	39	16	immunosensor	immunosensor	NOUN
ajst-32245	39	17	based	base	VERB
ajst-32245	39	18	on	on	ADP
ajst-32245	39	19	indium	indium	NOUN
ajst-32245	39	20	tin	tin	NOUN
ajst-32245	39	21	oxide	oxide	NOUN
ajst-32245	39	22	–	–	PUNCT
ajst-32245	39	23	polyethylene	polyethylene	NOUN
ajst-32245	39	24	terephthalate	terephthalate	NOUN
ajst-32245	39	25	(	(	PUNCT
ajst-32245	39	26	ito	ito	NOUN
ajst-32245	39	27	-	-	ADJ
ajst-32245	39	28	pet	pet	ADJ
ajst-32245	39	29	)	)	PUNCT
ajst-32245	39	30	electrodes	electrode	VERB
ajst-32245	39	31	modified	modify	VERB
ajst-32245	39	32	with	with	ADP
ajst-32245	39	33	3	3	NUM
ajst-32245	39	34	-	-	PUNCT
ajst-32245	39	35	glycidyloxypropyltrimethoxysilane	glycidyloxypropyltrimethoxysilane	NOUN
ajst-32245	39	36	(	(	PUNCT
ajst-32245	39	37	gpdmms	gpdmms	NOUN
ajst-32245	39	38	)	)	PUNCT
ajst-32245	39	39	and	and	CCONJ
ajst-32245	39	40	specific	specific	ADJ
ajst-32245	39	41	anti	anti	ADJ
ajst-32245	39	42	-	-	ADJ
ajst-32245	39	43	aβ42	aβ42	ADJ
ajst-32245	39	44	antibodies	antibodie	VERB
ajst-32245	39	45	,	,	PUNCT
ajst-32245	39	46	which	which	PRON
ajst-32245	39	47	enabled	enable	VERB
ajst-32245	39	48	rapid	rapid	ADJ
ajst-32245	39	49	,	,	PUNCT
ajst-32245	39	50	selective	selective	ADJ
ajst-32245	39	51	,	,	PUNCT
ajst-32245	39	52	and	and	CCONJ
ajst-32245	39	53	highly	highly	ADV
ajst-32245	39	54	sensitive	sensitive	ADJ
ajst-32245	39	55	quantification	quantification	NOUN
ajst-32245	39	56	26	26	NUM
ajst-32245	39	57	of	of	ADP
ajst-32245	39	58	aβ42	aβ42	PROPN
ajst-32245	40	1	[	[	X
ajst-32245	40	2	9	9	NUM
ajst-32245	40	3	]	]	PUNCT
ajst-32245	40	4	.	.	PUNCT
ajst-32245	41	1	in	in	ADP
ajst-32245	41	2	addition	addition	NOUN
ajst-32245	41	3	,	,	PUNCT
ajst-32245	41	4	molecularly	molecularly	ADV
ajst-32245	41	5	imprinted	imprint	VERB
ajst-32245	41	6	polypyrrole	polypyrrole	NOUN
ajst-32245	41	7	-	-	PUNCT
ajst-32245	41	8	based	base	VERB
ajst-32245	41	9	biosensors	biosensor	NOUN
ajst-32245	41	10	have	have	AUX
ajst-32245	41	11	utilized	utilize	VERB
ajst-32245	41	12	artificial	artificial	ADJ
ajst-32245	41	13	receptors	receptor	NOUN
ajst-32245	41	14	to	to	PART
ajst-32245	41	15	achieve	achieve	VERB
ajst-32245	41	16	specific	specific	ADJ
ajst-32245	41	17	recognition	recognition	NOUN
ajst-32245	41	18	of	of	ADP
ajst-32245	41	19	aβ	aβ	NOUN
ajst-32245	41	20	[	[	X
ajst-32245	41	21	13	13	NUM
ajst-32245	41	22	]	]	PUNCT
ajst-32245	41	23	.	.	PUNCT
ajst-32245	42	1	tau	tau	PROPN
ajst-32245	42	2	proteins	protein	NOUN
ajst-32245	42	3	,	,	PUNCT
ajst-32245	42	4	especially	especially	ADV
ajst-32245	42	5	their	their	PRON
ajst-32245	42	6	phosphorylated	phosphorylate	VERB
ajst-32245	42	7	forms	form	NOUN
ajst-32245	42	8	(	(	PUNCT
ajst-32245	42	9	p	p	X
ajst-32245	42	10	-	-	PUNCT
ajst-32245	42	11	tau181	tau181	PROPN
ajst-32245	42	12	and	and	CCONJ
ajst-32245	42	13	p	p	PROPN
ajst-32245	42	14	-	-	PUNCT
ajst-32245	42	15	tau231	tau231	NOUN
ajst-32245	42	16	)	)	PUNCT
ajst-32245	42	17	,	,	PUNCT
ajst-32245	42	18	also	also	ADV
ajst-32245	42	19	serve	serve	VERB
ajst-32245	42	20	as	as	ADP
ajst-32245	42	21	essential	essential	ADJ
ajst-32245	42	22	biomarkers	biomarker	NOUN
ajst-32245	42	23	for	for	ADP
ajst-32245	42	24	ad	ad	NOUN
ajst-32245	42	25	[	[	X
ajst-32245	42	26	14,15	14,15	NUM
ajst-32245	42	27	]	]	PUNCT
ajst-32245	42	28	.	.	PUNCT
ajst-32245	43	1	to	to	PART
ajst-32245	43	2	facilitate	facilitate	VERB
ajst-32245	43	3	their	their	PRON
ajst-32245	43	4	detection	detection	NOUN
ajst-32245	43	5	,	,	PUNCT
ajst-32245	43	6	nucleic	nucleic	ADJ
ajst-32245	43	7	acid	acid	NOUN
ajst-32245	43	8	aptamer	aptamer	NOUN
ajst-32245	43	9	-	-	PUNCT
ajst-32245	43	10	based	base	VERB
ajst-32245	43	11	electrochemical	electrochemical	ADJ
ajst-32245	43	12	sensors	sensor	NOUN
ajst-32245	43	13	have	have	AUX
ajst-32245	43	14	been	be	AUX
ajst-32245	43	15	developed	develop	VERB
ajst-32245	43	16	for	for	ADP
ajst-32245	43	17	identifying	identify	VERB
ajst-32245	43	18	serum	serum	NOUN
ajst-32245	43	19	p	p	PROPN
ajst-32245	43	20	-	-	PUNCT
ajst-32245	43	21	tau231	tau231	PROPN
ajst-32245	43	22	,	,	PUNCT
ajst-32245	43	23	offering	offer	VERB
ajst-32245	43	24	promise	promise	NOUN
ajst-32245	43	25	for	for	ADP
ajst-32245	43	26	rapid	rapid	ADJ
ajst-32245	43	27	ad	ad	NOUN
ajst-32245	43	28	screening	screening	NOUN
ajst-32245	43	29	[	[	X
ajst-32245	43	30	16	16	NUM
ajst-32245	43	31	]	]	PUNCT
ajst-32245	43	32	.	.	PUNCT
ajst-32245	44	1	furthermore	furthermore	ADV
ajst-32245	44	2	,	,	PUNCT
ajst-32245	44	3	electrochemical	electrochemical	ADJ
ajst-32245	44	4	biosensors	biosensor	NOUN
ajst-32245	44	5	integrating	integrate	VERB
ajst-32245	44	6	bifunctional	bifunctional	ADJ
ajst-32245	44	7	nanozyme	nanozyme	NOUN
ajst-32245	44	8	-	-	PUNCT
ajst-32245	44	9	based	base	VERB
ajst-32245	44	10	signal	signal	NOUN
ajst-32245	44	11	amplifiers	amplifier	NOUN
ajst-32245	44	12	have	have	AUX
ajst-32245	44	13	been	be	AUX
ajst-32245	44	14	reported	report	VERB
ajst-32245	44	15	,	,	PUNCT
ajst-32245	44	16	significantly	significantly	ADV
ajst-32245	44	17	enhancing	enhance	VERB
ajst-32245	44	18	the	the	DET
ajst-32245	44	19	sensitivity	sensitivity	NOUN
ajst-32245	44	20	of	of	ADP
ajst-32245	44	21	tau	tau	PROPN
ajst-32245	44	22	protein	protein	NOUN
ajst-32245	44	23	detection	detection	NOUN
ajst-32245	45	1	[	[	X
ajst-32245	45	2	17	17	NUM
ajst-32245	45	3	]	]	PUNCT
ajst-32245	45	4	.	.	PUNCT
ajst-32245	46	1	exosomal	exosomal	ADJ
ajst-32245	46	2	mirnas	mirna	NOUN
ajst-32245	46	3	represent	represent	VERB
ajst-32245	46	4	another	another	DET
ajst-32245	46	5	promising	promising	ADJ
ajst-32245	46	6	class	class	NOUN
ajst-32245	46	7	of	of	ADP
ajst-32245	46	8	biomarkers	biomarker	NOUN
ajst-32245	46	9	,	,	PUNCT
ajst-32245	46	10	with	with	ADP
ajst-32245	46	11	electrochemical	electrochemical	ADJ
ajst-32245	46	12	biosensors	biosensor	NOUN
ajst-32245	46	13	demonstrating	demonstrate	VERB
ajst-32245	46	14	the	the	DET
ajst-32245	46	15	capability	capability	NOUN
ajst-32245	46	16	to	to	PART
ajst-32245	46	17	detect	detect	VERB
ajst-32245	46	18	mirna-34a	mirna-34a	NOUN
ajst-32245	46	19	cost	cost	NOUN
ajst-32245	46	20	-	-	PUNCT
ajst-32245	46	21	effectively	effectively	ADV
ajst-32245	46	22	and	and	CCONJ
ajst-32245	46	23	non	non	ADJ
ajst-32245	46	24	-	-	ADJ
ajst-32245	46	25	invasively	invasively	ADV
ajst-32245	46	26	[	[	X
ajst-32245	46	27	18	18	NUM
ajst-32245	46	28	]	]	PUNCT
ajst-32245	46	29	.	.	PUNCT
ajst-32245	47	1	moreover	moreover	ADV
ajst-32245	47	2	,	,	PUNCT
ajst-32245	47	3	programmable	programmable	ADJ
ajst-32245	47	4	plasmonic	plasmonic	ADJ
ajst-32245	47	5	nanostructure	nanostructure	NOUN
ajst-32245	47	6	biosensors	biosensor	NOUN
ajst-32245	47	7	have	have	AUX
ajst-32245	47	8	enabled	enable	VERB
ajst-32245	47	9	the	the	DET
ajst-32245	47	10	precise	precise	ADJ
ajst-32245	47	11	quantification	quantification	NOUN
ajst-32245	47	12	of	of	ADP
ajst-32245	47	13	circulating	circulate	VERB
ajst-32245	47	14	exosomal	exosomal	ADJ
ajst-32245	47	15	mirnas	mirna	NOUN
ajst-32245	47	16	[	[	X
ajst-32245	47	17	19	19	NUM
ajst-32245	47	18	]	]	PUNCT
ajst-32245	47	19	.	.	PUNCT
ajst-32245	48	1	although	although	SCONJ
ajst-32245	48	2	most	most	ADJ
ajst-32245	48	3	of	of	ADP
ajst-32245	48	4	these	these	DET
ajst-32245	48	5	systems	system	NOUN
ajst-32245	48	6	are	be	AUX
ajst-32245	48	7	based	base	VERB
ajst-32245	48	8	on	on	ADP
ajst-32245	48	9	electrochemical	electrochemical	ADJ
ajst-32245	48	10	principles	principle	NOUN
ajst-32245	48	11	,	,	PUNCT
ajst-32245	48	12	their	their	PRON
ajst-32245	48	13	success	success	NOUN
ajst-32245	48	14	in	in	ADP
ajst-32245	48	15	biomarker	biomarker	NOUN
ajst-32245	48	16	detection	detection	NOUN
ajst-32245	48	17	provides	provide	VERB
ajst-32245	48	18	a	a	DET
ajst-32245	48	19	solid	solid	ADJ
ajst-32245	48	20	foundation	foundation	NOUN
ajst-32245	48	21	for	for	ADP
ajst-32245	48	22	expanding	expand	VERB
ajst-32245	48	23	into	into	ADP
ajst-32245	48	24	optical	optical	ADJ
ajst-32245	48	25	biosensor	biosensor	NOUN
ajst-32245	48	26	approaches	approach	NOUN
ajst-32245	48	27	.	.	PUNCT
ajst-32245	49	1	given	give	VERB
ajst-32245	49	2	single	single	ADJ
ajst-32245	49	3	plasma	plasma	NOUN
ajst-32245	49	4	biomarkers	biomarker	NOUN
ajst-32245	49	5	'	'	PART
ajst-32245	49	6	relatively	relatively	ADV
ajst-32245	49	7	low	low	ADJ
ajst-32245	49	8	diagnostic	diagnostic	ADJ
ajst-32245	49	9	accuracy	accuracy	NOUN
ajst-32245	49	10	,	,	PUNCT
ajst-32245	49	11	multiplexed	multiplexed	ADJ
ajst-32245	49	12	detection	detection	NOUN
ajst-32245	49	13	strategies	strategy	NOUN
ajst-32245	49	14	have	have	AUX
ajst-32245	49	15	attracted	attract	VERB
ajst-32245	49	16	considerable	considerable	ADJ
ajst-32245	49	17	attention	attention	NOUN
ajst-32245	49	18	for	for	ADP
ajst-32245	49	19	improving	improve	VERB
ajst-32245	49	20	ad	ad	NOUN
ajst-32245	49	21	diagnosis	diagnosis	NOUN
ajst-32245	49	22	[	[	X
ajst-32245	49	23	20	20	NUM
ajst-32245	49	24	]	]	PUNCT
ajst-32245	49	25	.	.	PUNCT
ajst-32245	50	1	recent	recent	ADJ
ajst-32245	50	2	studies	study	NOUN
ajst-32245	50	3	have	have	AUX
ajst-32245	50	4	reported	report	VERB
ajst-32245	50	5	electrochemical	electrochemical	ADJ
ajst-32245	50	6	biosensors	biosensor	NOUN
ajst-32245	50	7	capable	capable	ADJ
ajst-32245	50	8	of	of	ADP
ajst-32245	50	9	simultaneously	simultaneously	ADV
ajst-32245	50	10	detecting	detect	VERB
ajst-32245	50	11	multiple	multiple	ADJ
ajst-32245	50	12	ad	ad	NOUN
ajst-32245	50	13	biomarkers	biomarker	NOUN
ajst-32245	50	14	.	.	PUNCT
ajst-32245	51	1	for	for	ADP
ajst-32245	51	2	instance	instance	NOUN
ajst-32245	51	3	,	,	PUNCT
ajst-32245	51	4	a	a	DET
ajst-32245	51	5	printed	print	VERB
ajst-32245	51	6	electrochemical	electrochemical	ADJ
ajst-32245	51	7	biosensor	biosensor	NOUN
ajst-32245	51	8	based	base	VERB
ajst-32245	51	9	on	on	ADP
ajst-32245	51	10	vertical	vertical	ADJ
ajst-32245	51	11	graphene	graphene	NOUN
ajst-32245	51	12	(	(	PUNCT
ajst-32245	51	13	vg	vg	NOUN
ajst-32245	51	14	)	)	PUNCT
ajst-32245	51	15	modified	modify	VERB
ajst-32245	51	16	with	with	ADP
ajst-32245	51	17	gold	gold	ADJ
ajst-32245	51	18	nanoparticles	nanoparticle	NOUN
ajst-32245	51	19	(	(	PUNCT
ajst-32245	51	20	vg@nanoau	vg@nanoau	PROPN
ajst-32245	51	21	)	)	PUNCT
ajst-32245	51	22	enabled	enable	VERB
ajst-32245	51	23	the	the	DET
ajst-32245	51	24	concurrent	concurrent	ADJ
ajst-32245	51	25	detection	detection	NOUN
ajst-32245	51	26	of	of	ADP
ajst-32245	51	27	four	four	NUM
ajst-32245	51	28	plasma	plasma	NOUN
ajst-32245	51	29	biomarkers	biomarker	NOUN
ajst-32245	51	30	—	—	PUNCT
ajst-32245	51	31	aβ40	aβ40	PROPN
ajst-32245	51	32	,	,	PUNCT
ajst-32245	51	33	aβ42	aβ42	PROPN
ajst-32245	51	34	,	,	PUNCT
ajst-32245	51	35	t	t	PROPN
ajst-32245	51	36	-	-	PUNCT
ajst-32245	51	37	tau	tau	PROPN
ajst-32245	51	38	,	,	PUNCT
ajst-32245	51	39	and	and	CCONJ
ajst-32245	51	40	p	p	X
ajst-32245	51	41	-	-	PUNCT
ajst-32245	51	42	tau181	tau181	PROPN
ajst-32245	51	43	—	—	PUNCT
ajst-32245	51	44	thus	thus	ADV
ajst-32245	51	45	facilitating	facilitate	VERB
ajst-32245	51	46	multidimensional	multidimensional	ADJ
ajst-32245	51	47	biomarker	biomarker	NOUN
ajst-32245	51	48	analysis	analysis	NOUN
ajst-32245	51	49	[	[	X
ajst-32245	51	50	20	20	NUM
ajst-32245	51	51	]	]	PUNCT
ajst-32245	51	52	.	.	PUNCT
ajst-32245	52	1	similarly	similarly	ADV
ajst-32245	52	2	,	,	PUNCT
ajst-32245	52	3	an	an	DET
ajst-32245	52	4	electrochemical	electrochemical	ADJ
ajst-32245	52	5	immunosensor	immunosensor	NOUN
ajst-32245	52	6	utilizing	utilize	VERB
ajst-32245	52	7	a	a	DET
ajst-32245	52	8	superhydrophilic	superhydrophilic	ADJ
ajst-32245	52	9	droplet	droplet	ADJ
ajst-32245	52	10	array	array	NOUN
ajst-32245	52	11	could	could	AUX
ajst-32245	52	12	detect	detect	VERB
ajst-32245	52	13	the	the	DET
ajst-32245	52	14	same	same	ADJ
ajst-32245	52	15	panel	panel	NOUN
ajst-32245	52	16	of	of	ADP
ajst-32245	52	17	biomarkers	biomarker	NOUN
ajst-32245	52	18	,	,	PUNCT
ajst-32245	52	19	further	far	ADV
ajst-32245	52	20	supporting	support	VERB
ajst-32245	52	21	the	the	DET
ajst-32245	52	22	potential	potential	NOUN
ajst-32245	52	23	of	of	ADP
ajst-32245	52	24	multiplexed	multiplexed	ADJ
ajst-32245	52	25	approaches	approach	NOUN
ajst-32245	52	26	in	in	ADP
ajst-32245	52	27	enhancing	enhance	VERB
ajst-32245	52	28	diagnostic	diagnostic	ADJ
ajst-32245	52	29	performance	performance	NOUN
ajst-32245	52	30	[	[	X
ajst-32245	52	31	14	14	NUM
ajst-32245	52	32	]	]	PUNCT
ajst-32245	52	33	.	.	PUNCT
ajst-32245	53	1	electrochemical	electrochemical	ADJ
ajst-32245	53	2	biosensors	biosensor	NOUN
ajst-32245	53	3	for	for	ADP
ajst-32245	53	4	ad	ad	NOUN
ajst-32245	53	5	biomarker	biomarker	NOUN
ajst-32245	53	6	detection	detection	NOUN
ajst-32245	53	7	commonly	commonly	ADV
ajst-32245	53	8	employ	employ	VERB
ajst-32245	53	9	techniques	technique	NOUN
ajst-32245	53	10	such	such	ADJ
ajst-32245	53	11	as	as	ADP
ajst-32245	53	12	electrochemical	electrochemical	ADJ
ajst-32245	53	13	impedance	impedance	NOUN
ajst-32245	53	14	spectroscopy	spectroscopy	NOUN
ajst-32245	53	15	(	(	PUNCT
ajst-32245	53	16	eis	eis	PROPN
ajst-32245	53	17	)	)	PUNCT
ajst-32245	53	18	,	,	PUNCT
ajst-32245	53	19	cyclic	cyclic	ADJ
ajst-32245	53	20	voltammetry	voltammetry	NOUN
ajst-32245	53	21	(	(	PUNCT
ajst-32245	53	22	cv	cv	PROPN
ajst-32245	53	23	)	)	PUNCT
ajst-32245	53	24	,	,	PUNCT
ajst-32245	53	25	and	and	CCONJ
ajst-32245	53	26	differential	differential	ADJ
ajst-32245	53	27	pulse	pulse	NOUN
ajst-32245	53	28	voltammetry	voltammetry	NOUN
ajst-32245	53	29	(	(	PUNCT
ajst-32245	53	30	dpv	dpv	PROPN
ajst-32245	53	31	)	)	PUNCT
ajst-32245	54	1	[	[	X
ajst-32245	54	2	21	21	NUM
ajst-32245	54	3	]	]	PUNCT
ajst-32245	54	4	.	.	PUNCT
ajst-32245	55	1	for	for	ADP
ajst-32245	55	2	instance	instance	NOUN
ajst-32245	55	3	,	,	PUNCT
ajst-32245	55	4	an	an	DET
ajst-32245	55	5	impedance	impedance	NOUN
ajst-32245	55	6	-	-	PUNCT
ajst-32245	55	7	based	base	VERB
ajst-32245	55	8	biosensor	biosensor	NOUN
ajst-32245	55	9	enabled	enable	VERB
ajst-32245	55	10	label	label	NOUN
ajst-32245	55	11	-	-	PUNCT
ajst-32245	55	12	free	free	ADJ
ajst-32245	55	13	quantification	quantification	NOUN
ajst-32245	55	14	of	of	ADP
ajst-32245	55	15	plasma	plasma	NOUN
ajst-32245	55	16	p	p	PROPN
ajst-32245	55	17	-	-	PUNCT
ajst-32245	55	18	tau181	tau181	PROPN
ajst-32245	55	19	,	,	PUNCT
ajst-32245	55	20	distinguishing	distinguish	VERB
ajst-32245	55	21	individuals	individual	NOUN
ajst-32245	55	22	with	with	ADP
ajst-32245	55	23	mild	mild	ADJ
ajst-32245	55	24	cognitive	cognitive	ADJ
ajst-32245	55	25	impairment	impairment	NOUN
ajst-32245	55	26	,	,	PUNCT
ajst-32245	55	27	ad	ad	NOUN
ajst-32245	55	28	patients	patient	NOUN
ajst-32245	55	29	,	,	PUNCT
ajst-32245	55	30	and	and	CCONJ
ajst-32245	55	31	healthy	healthy	ADJ
ajst-32245	55	32	participants	participant	NOUN
ajst-32245	55	33	[	[	X
ajst-32245	55	34	15	15	NUM
ajst-32245	55	35	]	]	PUNCT
ajst-32245	55	36	.	.	PUNCT
ajst-32245	56	1	the	the	DET
ajst-32245	56	2	advancement	advancement	NOUN
ajst-32245	56	3	of	of	ADP
ajst-32245	56	4	biosensors	biosensor	NOUN
ajst-32245	56	5	in	in	ADP
ajst-32245	56	6	early	early	ADJ
ajst-32245	56	7	ad	ad	NOUN
ajst-32245	56	8	diagnosis	diagnosis	NOUN
ajst-32245	56	9	has	have	AUX
ajst-32245	56	10	greatly	greatly	ADV
ajst-32245	56	11	facilitated	facilitate	VERB
ajst-32245	56	12	early	early	ADJ
ajst-32245	56	13	intervention	intervention	NOUN
ajst-32245	56	14	and	and	CCONJ
ajst-32245	56	15	management	management	NOUN
ajst-32245	56	16	.	.	PUNCT
ajst-32245	57	1	these	these	DET
ajst-32245	57	2	devices	device	NOUN
ajst-32245	57	3	offer	offer	VERB
ajst-32245	57	4	non	non	ADJ
ajst-32245	57	5	-	-	ADJ
ajst-32245	57	6	invasive	invasive	ADJ
ajst-32245	57	7	,	,	PUNCT
ajst-32245	57	8	low	low	ADJ
ajst-32245	57	9	-	-	PUNCT
ajst-32245	57	10	cost	cost	NOUN
ajst-32245	57	11	,	,	PUNCT
ajst-32245	57	12	and	and	CCONJ
ajst-32245	57	13	rapid	rapid	ADJ
ajst-32245	57	14	diagnostic	diagnostic	ADJ
ajst-32245	57	15	tools	tool	NOUN
ajst-32245	57	16	suitable	suitable	ADJ
ajst-32245	57	17	for	for	ADP
ajst-32245	57	18	large	large	ADJ
ajst-32245	57	19	-	-	PUNCT
ajst-32245	57	20	scale	scale	NOUN
ajst-32245	57	21	screening	screening	NOUN
ajst-32245	57	22	and	and	CCONJ
ajst-32245	57	23	point	point	NOUN
ajst-32245	57	24	-	-	PUNCT
ajst-32245	57	25	of	of	ADP
ajst-32245	57	26	-	-	PUNCT
ajst-32245	57	27	care	care	NOUN
ajst-32245	57	28	testing	testing	NOUN
ajst-32245	57	29	(	(	PUNCT
ajst-32245	57	30	poct	poct	NOUN
ajst-32245	57	31	)	)	PUNCT
ajst-32245	58	1	[	[	X
ajst-32245	58	2	22	22	NUM
ajst-32245	58	3	]	]	PUNCT
ajst-32245	58	4	.	.	PUNCT
ajst-32245	59	1	by	by	ADP
ajst-32245	59	2	detecting	detect	VERB
ajst-32245	59	3	ad	ad	NOUN
ajst-32245	59	4	biomarkers	biomarker	NOUN
ajst-32245	59	5	in	in	ADP
ajst-32245	59	6	blood	blood	NOUN
ajst-32245	59	7	,	,	PUNCT
ajst-32245	59	8	they	they	PRON
ajst-32245	59	9	provide	provide	VERB
ajst-32245	59	10	the	the	DET
ajst-32245	59	11	potential	potential	NOUN
ajst-32245	59	12	to	to	PART
ajst-32245	59	13	diagnose	diagnose	VERB
ajst-32245	59	14	the	the	DET
ajst-32245	59	15	disease	disease	NOUN
ajst-32245	59	16	before	before	SCONJ
ajst-32245	59	17	clinical	clinical	ADJ
ajst-32245	59	18	symptoms	symptom	NOUN
ajst-32245	59	19	emerge	emerge	VERB
ajst-32245	59	20	,	,	PUNCT
ajst-32245	59	21	even	even	ADV
ajst-32245	59	22	during	during	ADP
ajst-32245	59	23	asymptomatic	asymptomatic	ADJ
ajst-32245	59	24	stages	stage	NOUN
ajst-32245	59	25	,	,	PUNCT
ajst-32245	59	26	thereby	thereby	ADV
ajst-32245	59	27	affording	afford	VERB
ajst-32245	59	28	valuable	valuable	ADJ
ajst-32245	59	29	treatment	treatment	NOUN
ajst-32245	59	30	time	time	NOUN
ajst-32245	59	31	and	and	CCONJ
ajst-32245	59	32	mitigating	mitigate	VERB
ajst-32245	59	33	ad	ad	NOUN
ajst-32245	59	34	's	's	PART
ajst-32245	59	35	social	social	ADJ
ajst-32245	59	36	and	and	CCONJ
ajst-32245	59	37	economic	economic	ADJ
ajst-32245	59	38	burden	burden	NOUN
ajst-32245	59	39	.	.	PUNCT
ajst-32245	60	1	future	future	ADJ
ajst-32245	60	2	research	research	NOUN
ajst-32245	60	3	on	on	ADP
ajst-32245	60	4	electrochemical	electrochemical	ADJ
ajst-32245	60	5	biosensors	biosensor	NOUN
ajst-32245	60	6	for	for	ADP
ajst-32245	60	7	the	the	DET
ajst-32245	60	8	early	early	ADJ
ajst-32245	60	9	diagnosis	diagnosis	NOUN
ajst-32245	60	10	of	of	ADP
ajst-32245	60	11	alzheimer	alzheimer	PROPN
ajst-32245	60	12	’s	’s	PART
ajst-32245	60	13	disease	disease	NOUN
ajst-32245	60	14	(	(	PUNCT
ajst-32245	60	15	ad	ad	NOUN
ajst-32245	60	16	)	)	PUNCT
ajst-32245	60	17	is	be	AUX
ajst-32245	60	18	expected	expect	VERB
ajst-32245	60	19	to	to	PART
ajst-32245	60	20	advance	advance	VERB
ajst-32245	60	21	along	along	ADP
ajst-32245	60	22	several	several	ADJ
ajst-32245	60	23	promising	promising	ADJ
ajst-32245	60	24	directions	direction	NOUN
ajst-32245	60	25	.	.	PUNCT
ajst-32245	61	1	one	one	NUM
ajst-32245	61	2	important	important	ADJ
ajst-32245	61	3	avenue	avenue	NOUN
ajst-32245	61	4	is	be	AUX
ajst-32245	61	5	the	the	DET
ajst-32245	61	6	development	development	NOUN
ajst-32245	61	7	of	of	ADP
ajst-32245	61	8	multimodal	multimodal	ADJ
ajst-32245	61	9	sensing	sense	VERB
ajst-32245	61	10	platforms	platform	NOUN
ajst-32245	61	11	that	that	PRON
ajst-32245	61	12	integrate	integrate	VERB
ajst-32245	61	13	electrochemical	electrochemical	ADJ
ajst-32245	61	14	methods	method	NOUN
ajst-32245	61	15	with	with	ADP
ajst-32245	61	16	other	other	ADJ
ajst-32245	61	17	detection	detection	NOUN
ajst-32245	61	18	modalities	modality	NOUN
ajst-32245	61	19	,	,	PUNCT
ajst-32245	61	20	such	such	ADJ
ajst-32245	61	21	as	as	ADP
ajst-32245	61	22	optical	optical	ADJ
ajst-32245	61	23	and	and	CCONJ
ajst-32245	61	24	acoustic	acoustic	ADJ
ajst-32245	61	25	techniques	technique	NOUN
ajst-32245	61	26	.	.	PUNCT
ajst-32245	62	1	this	this	DET
ajst-32245	62	2	combination	combination	NOUN
ajst-32245	62	3	allows	allow	VERB
ajst-32245	62	4	for	for	ADP
ajst-32245	62	5	cross	cross	NOUN
ajst-32245	62	6	-	-	NOUN
ajst-32245	62	7	validation	validation	NOUN
ajst-32245	62	8	of	of	ADP
ajst-32245	62	9	signals	signal	NOUN
ajst-32245	62	10	and	and	CCONJ
ajst-32245	62	11	amplification	amplification	NOUN
ajst-32245	62	12	of	of	ADP
ajst-32245	62	13	responses	response	NOUN
ajst-32245	62	14	,	,	PUNCT
ajst-32245	62	15	thereby	thereby	ADV
ajst-32245	62	16	further	far	ADV
ajst-32245	62	17	enhancing	enhance	VERB
ajst-32245	62	18	sensitivity	sensitivity	NOUN
ajst-32245	62	19	and	and	CCONJ
ajst-32245	62	20	diagnostic	diagnostic	ADJ
ajst-32245	62	21	accuracy	accuracy	NOUN
ajst-32245	62	22	.	.	PUNCT
ajst-32245	63	1	terahertz	terahertz	NOUN
ajst-32245	63	2	metamaterial	metamaterial	ADJ
ajst-32245	63	3	sensors	sensor	NOUN
ajst-32245	63	4	,	,	PUNCT
ajst-32245	63	5	in	in	ADP
ajst-32245	63	6	particular	particular	ADJ
ajst-32245	63	7	,	,	PUNCT
ajst-32245	63	8	have	have	AUX
ajst-32245	63	9	shown	show	VERB
ajst-32245	63	10	considerable	considerable	ADJ
ajst-32245	63	11	potential	potential	NOUN
ajst-32245	63	12	in	in	ADP
ajst-32245	63	13	biosensing	biosense	VERB
ajst-32245	63	14	applications	application	NOUN
ajst-32245	63	15	and	and	CCONJ
ajst-32245	63	16	may	may	AUX
ajst-32245	63	17	be	be	AUX
ajst-32245	63	18	coupled	couple	VERB
ajst-32245	63	19	with	with	ADP
ajst-32245	63	20	electrochemical	electrochemical	ADJ
ajst-32245	63	21	strategies	strategy	NOUN
ajst-32245	63	22	to	to	PART
ajst-32245	63	23	achieve	achieve	VERB
ajst-32245	63	24	high	high	ADJ
ajst-32245	63	25	-	-	PUNCT
ajst-32245	63	26	sensitivity	sensitivity	NOUN
ajst-32245	63	27	detection	detection	NOUN
ajst-32245	63	28	of	of	ADP
ajst-32245	63	29	biomolecules	biomolecule	NOUN
ajst-32245	63	30	,	,	PUNCT
ajst-32245	63	31	microorganisms	microorganism	NOUN
ajst-32245	63	32	,	,	PUNCT
ajst-32245	63	33	and	and	CCONJ
ajst-32245	63	34	cells	cell	NOUN
ajst-32245	64	1	[	[	X
ajst-32245	64	2	23	23	NUM
ajst-32245	64	3	]	]	PUNCT
ajst-32245	64	4	.	.	PUNCT
ajst-32245	65	1	another	another	DET
ajst-32245	65	2	direction	direction	NOUN
ajst-32245	65	3	involves	involve	VERB
ajst-32245	65	4	expanding	expand	VERB
ajst-32245	65	5	the	the	DET
ajst-32245	65	6	scope	scope	NOUN
ajst-32245	65	7	of	of	ADP
ajst-32245	65	8	so	so	ADV
ajst-32245	65	9	-	-	PUNCT
ajst-32245	65	10	called	call	VERB
ajst-32245	65	11	“	"	PUNCT
ajst-32245	65	12	liquid	liquid	ADJ
ajst-32245	65	13	biopsy	biopsy	NOUN
ajst-32245	65	14	”	"	PUNCT
ajst-32245	65	15	applications	application	NOUN
ajst-32245	65	16	.	.	PUNCT
ajst-32245	66	1	while	while	SCONJ
ajst-32245	66	2	blood	blood	NOUN
ajst-32245	66	3	remains	remain	VERB
ajst-32245	66	4	the	the	DET
ajst-32245	66	5	most	most	ADV
ajst-32245	66	6	commonly	commonly	ADV
ajst-32245	66	7	studied	study	VERB
ajst-32245	66	8	sample	sample	NOUN
ajst-32245	66	9	,	,	PUNCT
ajst-32245	66	10	other	other	ADJ
ajst-32245	66	11	bodily	bodily	ADJ
ajst-32245	66	12	fluids	fluid	NOUN
ajst-32245	66	13	such	such	ADJ
ajst-32245	66	14	as	as	ADP
ajst-32245	66	15	saliva	saliva	NOUN
ajst-32245	66	16	,	,	PUNCT
ajst-32245	66	17	urine	urine	NOUN
ajst-32245	66	18	,	,	PUNCT
ajst-32245	66	19	and	and	CCONJ
ajst-32245	66	20	tears	tear	NOUN
ajst-32245	66	21	represent	represent	VERB
ajst-32245	66	22	valuable	valuable	ADJ
ajst-32245	66	23	alternatives	alternative	NOUN
ajst-32245	66	24	for	for	ADP
ajst-32245	66	25	ad	ad	NOUN
ajst-32245	66	26	biomarker	biomarker	NOUN
ajst-32245	66	27	detection	detection	NOUN
ajst-32245	66	28	.	.	PUNCT
ajst-32245	67	1	exploring	explore	VERB
ajst-32245	67	2	these	these	DET
ajst-32245	67	3	less	less	ADV
ajst-32245	67	4	invasive	invasive	ADJ
ajst-32245	67	5	samples	sample	NOUN
ajst-32245	67	6	could	could	AUX
ajst-32245	67	7	significantly	significantly	ADV
ajst-32245	67	8	reduce	reduce	VERB
ajst-32245	67	9	patient	patient	ADJ
ajst-32245	67	10	discomfort	discomfort	NOUN
ajst-32245	67	11	and	and	CCONJ
ajst-32245	67	12	improve	improve	VERB
ajst-32245	67	13	compliance	compliance	NOUN
ajst-32245	67	14	while	while	SCONJ
ajst-32245	67	15	also	also	ADV
ajst-32245	67	16	broadening	broaden	VERB
ajst-32245	67	17	the	the	DET
ajst-32245	67	18	accessibility	accessibility	NOUN
ajst-32245	67	19	of	of	ADP
ajst-32245	67	20	diagnostic	diagnostic	ADJ
ajst-32245	67	21	testing	testing	NOUN
ajst-32245	67	22	.	.	PUNCT
ajst-32245	68	1	in	in	ADP
ajst-32245	68	2	addition	addition	NOUN
ajst-32245	68	3	,	,	PUNCT
ajst-32245	68	4	integrating	integrate	VERB
ajst-32245	68	5	electrochemical	electrochemical	ADJ
ajst-32245	68	6	biosensors	biosensor	NOUN
ajst-32245	68	7	with	with	ADP
ajst-32245	68	8	artificial	artificial	ADJ
ajst-32245	68	9	intelligence	intelligence	NOUN
ajst-32245	68	10	(	(	PUNCT
ajst-32245	68	11	ai	ai	NOUN
ajst-32245	68	12	)	)	PUNCT
ajst-32245	68	13	and	and	CCONJ
ajst-32245	68	14	big	big	ADJ
ajst-32245	68	15	data	datum	NOUN
ajst-32245	68	16	analytics	analytic	NOUN
ajst-32245	68	17	offers	offer	VERB
ajst-32245	68	18	substantial	substantial	ADJ
ajst-32245	68	19	opportunities	opportunity	NOUN
ajst-32245	68	20	for	for	ADP
ajst-32245	68	21	refining	refine	VERB
ajst-32245	68	22	diagnostic	diagnostic	ADJ
ajst-32245	68	23	models	model	NOUN
ajst-32245	68	24	.	.	PUNCT
ajst-32245	69	1	the	the	DET
ajst-32245	69	2	vast	vast	ADJ
ajst-32245	69	3	datasets	dataset	NOUN
ajst-32245	69	4	generated	generate	VERB
ajst-32245	69	5	by	by	ADP
ajst-32245	69	6	biosensor	biosensor	NOUN
ajst-32245	69	7	measurements	measurement	NOUN
ajst-32245	69	8	can	can	AUX
ajst-32245	69	9	be	be	AUX
ajst-32245	69	10	coupled	couple	VERB
ajst-32245	69	11	with	with	ADP
ajst-32245	69	12	ai	ai	ADP
ajst-32245	69	13	and	and	CCONJ
ajst-32245	69	14	machine	machine	NOUN
ajst-32245	69	15	learning	learn	VERB
ajst-32245	69	16	algorithms	algorithm	NOUN
ajst-32245	69	17	to	to	PART
ajst-32245	69	18	extract	extract	VERB
ajst-32245	69	19	complex	complex	ADJ
ajst-32245	69	20	patterns	pattern	NOUN
ajst-32245	69	21	that	that	PRON
ajst-32245	69	22	may	may	AUX
ajst-32245	69	23	be	be	AUX
ajst-32245	69	24	imperceptible	imperceptible	ADJ
ajst-32245	69	25	through	through	ADP
ajst-32245	69	26	traditional	traditional	ADJ
ajst-32245	69	27	analysis	analysis	NOUN
ajst-32245	69	28	.	.	PUNCT
ajst-32245	70	1	ai	ai	VERB
ajst-32245	70	2	has	have	AUX
ajst-32245	70	3	already	already	ADV
ajst-32245	70	4	demonstrated	demonstrate	VERB
ajst-32245	70	5	27	27	NUM
ajst-32245	70	6	distinct	distinct	ADJ
ajst-32245	70	7	advantages	advantage	NOUN
ajst-32245	70	8	in	in	ADP
ajst-32245	70	9	processing	process	VERB
ajst-32245	70	10	large	large	ADJ
ajst-32245	70	11	-	-	PUNCT
ajst-32245	70	12	scale	scale	NOUN
ajst-32245	70	13	and	and	CCONJ
ajst-32245	70	14	heterogeneous	heterogeneous	ADJ
ajst-32245	70	15	biomedical	biomedical	ADJ
ajst-32245	70	16	data	datum	NOUN
ajst-32245	70	17	,	,	PUNCT
ajst-32245	70	18	and	and	CCONJ
ajst-32245	70	19	its	its	PRON
ajst-32245	70	20	application	application	NOUN
ajst-32245	70	21	to	to	ADP
ajst-32245	70	22	early	early	ADJ
ajst-32245	70	23	ad	ad	NOUN
ajst-32245	70	24	detection	detection	NOUN
ajst-32245	70	25	is	be	AUX
ajst-32245	70	26	exemplified	exemplify	VERB
ajst-32245	70	27	by	by	ADP
ajst-32245	70	28	the	the	DET
ajst-32245	70	29	use	use	NOUN
ajst-32245	70	30	of	of	ADP
ajst-32245	70	31	deep	deep	ADJ
ajst-32245	70	32	learning	learning	NOUN
ajst-32245	70	33	for	for	ADP
ajst-32245	70	34	the	the	DET
ajst-32245	70	35	interpretation	interpretation	NOUN
ajst-32245	70	36	of	of	ADP
ajst-32245	70	37	mri	mri	NOUN
ajst-32245	70	38	images	image	NOUN
ajst-32245	70	39	.	.	PUNCT
ajst-32245	71	1	combining	combine	VERB
ajst-32245	71	2	such	such	ADJ
ajst-32245	71	3	approaches	approach	NOUN
ajst-32245	71	4	with	with	ADP
ajst-32245	71	5	biosensor	biosensor	NOUN
ajst-32245	71	6	-	-	PUNCT
ajst-32245	71	7	derived	derive	VERB
ajst-32245	71	8	data	datum	NOUN
ajst-32245	71	9	could	could	AUX
ajst-32245	71	10	create	create	VERB
ajst-32245	71	11	more	more	ADV
ajst-32245	71	12	robust	robust	ADJ
ajst-32245	71	13	,	,	PUNCT
ajst-32245	71	14	accurate	accurate	ADJ
ajst-32245	71	15	,	,	PUNCT
ajst-32245	71	16	and	and	CCONJ
ajst-32245	71	17	clinically	clinically	ADV
ajst-32245	71	18	applicable	applicable	ADJ
ajst-32245	71	19	diagnostic	diagnostic	ADJ
ajst-32245	71	20	systems	system	NOUN
ajst-32245	71	21	[	[	X
ajst-32245	71	22	24	24	NUM
ajst-32245	71	23	]	]	PUNCT
ajst-32245	71	24	.	.	PUNCT
ajst-32245	72	1	2.2	2.2	NUM
ajst-32245	72	2	emerging	emerge	VERB
ajst-32245	72	3	optical	optical	ADJ
ajst-32245	72	4	biosensing	biosensing	NOUN
ajst-32245	72	5	platforms	platform	NOUN
ajst-32245	72	6	and	and	CCONJ
ajst-32245	72	7	technologies	technology	NOUN
ajst-32245	72	8	2.2.1	2.2.1	NUM
ajst-32245	72	9	nanomaterial	nanomaterial	NOUN
ajst-32245	72	10	-	-	PUNCT
ajst-32245	72	11	enhanced	enhance	VERB
ajst-32245	72	12	optical	optical	ADJ
ajst-32245	72	13	sensing	sensing	NOUN
ajst-32245	72	14	owing	owe	VERB
ajst-32245	72	15	to	to	ADP
ajst-32245	72	16	their	their	PRON
ajst-32245	72	17	unique	unique	ADJ
ajst-32245	72	18	physicochemical	physicochemical	ADJ
ajst-32245	72	19	properties	property	NOUN
ajst-32245	72	20	,	,	PUNCT
ajst-32245	72	21	nanomaterials	nanomaterial	NOUN
ajst-32245	72	22	have	have	AUX
ajst-32245	72	23	been	be	AUX
ajst-32245	72	24	widely	widely	ADV
ajst-32245	72	25	employed	employ	VERB
ajst-32245	72	26	in	in	ADP
ajst-32245	72	27	constructing	construct	VERB
ajst-32245	72	28	optical	optical	ADJ
ajst-32245	72	29	biosensors	biosensor	NOUN
ajst-32245	72	30	to	to	PART
ajst-32245	72	31	enhance	enhance	VERB
ajst-32245	72	32	sensitivity	sensitivity	NOUN
ajst-32245	72	33	and	and	CCONJ
ajst-32245	72	34	selectivity	selectivity	NOUN
ajst-32245	72	35	[	[	X
ajst-32245	72	36	25	25	NUM
ajst-32245	72	37	]	]	PUNCT
ajst-32245	72	38	.	.	PUNCT
ajst-32245	73	1	nanoparticles	nanoparticle	NOUN
ajst-32245	73	2	,	,	PUNCT
ajst-32245	73	3	nanowires	nanowire	NOUN
ajst-32245	73	4	,	,	PUNCT
ajst-32245	73	5	and	and	CCONJ
ajst-32245	73	6	quantum	quantum	NOUN
ajst-32245	73	7	dots	dot	NOUN
ajst-32245	73	8	have	have	AUX
ajst-32245	73	9	demonstrated	demonstrate	VERB
ajst-32245	73	10	outstanding	outstanding	ADJ
ajst-32245	73	11	potential	potential	NOUN
ajst-32245	73	12	for	for	ADP
ajst-32245	73	13	detecting	detect	VERB
ajst-32245	73	14	ad	ad	NOUN
ajst-32245	73	15	-	-	PUNCT
ajst-32245	73	16	specific	specific	ADJ
ajst-32245	73	17	biomarkers	biomarker	NOUN
ajst-32245	73	18	.	.	PUNCT
ajst-32245	74	1	for	for	ADP
ajst-32245	74	2	example	example	NOUN
ajst-32245	74	3	,	,	PUNCT
ajst-32245	74	4	mxene	mxene	NOUN
ajst-32245	74	5	(	(	PUNCT
ajst-32245	74	6	ti₃c₂tₓ	ti₃c₂tₓ	NOUN
ajst-32245	74	7	)	)	PUNCT
ajst-32245	74	8	materials	material	NOUN
ajst-32245	74	9	,	,	PUNCT
ajst-32245	74	10	with	with	ADP
ajst-32245	74	11	their	their	PRON
ajst-32245	74	12	large	large	ADJ
ajst-32245	74	13	surface	surface	NOUN
ajst-32245	74	14	area	area	NOUN
ajst-32245	74	15	,	,	PUNCT
ajst-32245	74	16	biocompatibility	biocompatibility	NOUN
ajst-32245	74	17	,	,	PUNCT
ajst-32245	74	18	excellent	excellent	ADJ
ajst-32245	74	19	conductivity	conductivity	NOUN
ajst-32245	74	20	,	,	PUNCT
ajst-32245	74	21	and	and	CCONJ
ajst-32245	74	22	good	good	ADJ
ajst-32245	74	23	aqueous	aqueous	ADJ
ajst-32245	74	24	dispersibility	dispersibility	NOUN
ajst-32245	74	25	,	,	PUNCT
ajst-32245	74	26	have	have	AUX
ajst-32245	74	27	been	be	AUX
ajst-32245	74	28	applied	apply	VERB
ajst-32245	74	29	in	in	ADP
ajst-32245	74	30	the	the	DET
ajst-32245	74	31	development	development	NOUN
ajst-32245	74	32	of	of	ADP
ajst-32245	74	33	cholesteroldetecting	cholesteroldetecte	VERB
ajst-32245	74	34	biosensors	biosensor	NOUN
ajst-32245	74	35	;	;	PUNCT
ajst-32245	74	36	similar	similar	ADJ
ajst-32245	74	37	materials	material	NOUN
ajst-32245	74	38	are	be	AUX
ajst-32245	74	39	expected	expect	VERB
ajst-32245	74	40	to	to	PART
ajst-32245	74	41	be	be	AUX
ajst-32245	74	42	applicable	applicable	ADJ
ajst-32245	74	43	for	for	ADP
ajst-32245	74	44	ad	ad	NOUN
ajst-32245	74	45	biomarker	biomarker	NOUN
ajst-32245	74	46	detection	detection	NOUN
ajst-32245	75	1	[	[	X
ajst-32245	75	2	26	26	NUM
ajst-32245	75	3	]	]	PUNCT
ajst-32245	75	4	.	.	PUNCT
ajst-32245	76	1	2.2.2	2.2.2	NUM
ajst-32245	76	2	surface	surface	NOUN
ajst-32245	76	3	plasmon	plasmon	ADJ
ajst-32245	76	4	resonance	resonance	NOUN
ajst-32245	76	5	(	(	PUNCT
ajst-32245	76	6	spr	spr	ADJ
ajst-32245	76	7	)	)	PUNCT
ajst-32245	76	8	biosensors	biosensor	NOUN
ajst-32245	76	9	surface	surface	VERB
ajst-32245	76	10	plasmon	plasmon	ADJ
ajst-32245	76	11	resonance	resonance	NOUN
ajst-32245	76	12	(	(	PUNCT
ajst-32245	76	13	spr	spr	ADJ
ajst-32245	76	14	)	)	PUNCT
ajst-32245	76	15	biosensors	biosensor	NOUN
ajst-32245	76	16	are	be	AUX
ajst-32245	76	17	highly	highly	ADV
ajst-32245	76	18	sensitive	sensitive	ADJ
ajst-32245	76	19	optical	optical	ADJ
ajst-32245	76	20	analytical	analytical	ADJ
ajst-32245	76	21	tools	tool	NOUN
ajst-32245	76	22	based	base	VERB
ajst-32245	76	23	on	on	ADP
ajst-32245	76	24	the	the	DET
ajst-32245	76	25	principle	principle	NOUN
ajst-32245	76	26	of	of	ADP
ajst-32245	76	27	spr	spr	NOUN
ajst-32245	76	28	,	,	PUNCT
ajst-32245	76	29	which	which	PRON
ajst-32245	76	30	arises	arise	VERB
ajst-32245	76	31	from	from	ADP
ajst-32245	76	32	the	the	DET
ajst-32245	76	33	resonant	resonant	ADJ
ajst-32245	76	34	oscillation	oscillation	NOUN
ajst-32245	76	35	of	of	ADP
ajst-32245	76	36	free	free	ADJ
ajst-32245	76	37	electrons	electron	NOUN
ajst-32245	76	38	on	on	ADP
ajst-32245	76	39	a	a	DET
ajst-32245	76	40	metal	metal	NOUN
ajst-32245	76	41	film	film	NOUN
ajst-32245	76	42	under	under	ADP
ajst-32245	76	43	specific	specific	ADJ
ajst-32245	76	44	incident	incident	NOUN
ajst-32245	76	45	light	light	ADJ
ajst-32245	76	46	conditions	condition	NOUN
ajst-32245	76	47	.	.	PUNCT
ajst-32245	77	1	when	when	SCONJ
ajst-32245	77	2	light	light	NOUN
ajst-32245	77	3	impinges	impinge	VERB
ajst-32245	77	4	on	on	ADP
ajst-32245	77	5	the	the	DET
ajst-32245	77	6	metal	metal	NOUN
ajst-32245	77	7	–	–	PUNCT
ajst-32245	77	8	dielectric	dielectric	ADJ
ajst-32245	77	9	interface	interface	NOUN
ajst-32245	77	10	at	at	ADP
ajst-32245	77	11	a	a	DET
ajst-32245	77	12	particular	particular	ADJ
ajst-32245	77	13	angle	angle	NOUN
ajst-32245	77	14	,	,	PUNCT
ajst-32245	77	15	surface	surface	NOUN
ajst-32245	77	16	plasmons	plasmon	NOUN
ajst-32245	77	17	couple	couple	NOUN
ajst-32245	77	18	with	with	ADP
ajst-32245	77	19	the	the	DET
ajst-32245	77	20	electromagnetic	electromagnetic	ADJ
ajst-32245	77	21	waves	wave	NOUN
ajst-32245	77	22	of	of	ADP
ajst-32245	77	23	the	the	DET
ajst-32245	77	24	incident	incident	NOUN
ajst-32245	77	25	light	light	NOUN
ajst-32245	77	26	,	,	PUNCT
ajst-32245	77	27	leading	lead	VERB
ajst-32245	77	28	to	to	ADP
ajst-32245	77	29	a	a	DET
ajst-32245	77	30	significant	significant	ADJ
ajst-32245	77	31	change	change	NOUN
ajst-32245	77	32	in	in	ADP
ajst-32245	77	33	the	the	DET
ajst-32245	77	34	reflected	reflect	VERB
ajst-32245	77	35	light	light	ADJ
ajst-32245	77	36	intensity	intensity	NOUN
ajst-32245	77	37	.	.	PUNCT
ajst-32245	78	1	this	this	DET
ajst-32245	78	2	change	change	NOUN
ajst-32245	78	3	is	be	AUX
ajst-32245	78	4	susceptible	susceptible	ADJ
ajst-32245	78	5	to	to	ADP
ajst-32245	78	6	refractive	refractive	ADJ
ajst-32245	78	7	index	index	NOUN
ajst-32245	78	8	variations	variation	NOUN
ajst-32245	78	9	caused	cause	VERB
ajst-32245	78	10	by	by	ADP
ajst-32245	78	11	molecular	molecular	ADJ
ajst-32245	78	12	binding	binding	NOUN
ajst-32245	78	13	or	or	CCONJ
ajst-32245	78	14	dissociation	dissociation	NOUN
ajst-32245	78	15	at	at	ADP
ajst-32245	78	16	the	the	DET
ajst-32245	78	17	interface	interface	NOUN
ajst-32245	78	18	.	.	PUNCT
ajst-32245	79	1	by	by	ADP
ajst-32245	79	2	monitoring	monitor	VERB
ajst-32245	79	3	variations	variation	NOUN
ajst-32245	79	4	in	in	ADP
ajst-32245	79	5	the	the	DET
ajst-32245	79	6	angle	angle	NOUN
ajst-32245	79	7	or	or	CCONJ
ajst-32245	79	8	intensity	intensity	NOUN
ajst-32245	79	9	of	of	ADP
ajst-32245	79	10	the	the	DET
ajst-32245	79	11	reflected	reflect	VERB
ajst-32245	79	12	light	light	NOUN
ajst-32245	79	13	,	,	PUNCT
ajst-32245	79	14	spr	spr	ADJ
ajst-32245	79	15	biosensors	biosensor	NOUN
ajst-32245	79	16	enable	enable	VERB
ajst-32245	79	17	real	real	ADJ
ajst-32245	79	18	-	-	PUNCT
ajst-32245	79	19	time	time	NOUN
ajst-32245	79	20	,	,	PUNCT
ajst-32245	79	21	label	label	NOUN
ajst-32245	79	22	-	-	PUNCT
ajst-32245	79	23	free	free	ADJ
ajst-32245	79	24	detection	detection	NOUN
ajst-32245	79	25	of	of	ADP
ajst-32245	79	26	molecular	molecular	ADJ
ajst-32245	79	27	interactions	interaction	NOUN
ajst-32245	79	28	,	,	PUNCT
ajst-32245	79	29	such	such	ADJ
ajst-32245	79	30	as	as	ADP
ajst-32245	79	31	antigen	antigen	ADJ
ajst-32245	79	32	–	–	PUNCT
ajst-32245	79	33	antibody	antibody	NOUN
ajst-32245	79	34	binding	bind	VERB
ajst-32245	79	35	,	,	PUNCT
ajst-32245	79	36	nucleic	nucleic	ADJ
ajst-32245	79	37	acid	acid	NOUN
ajst-32245	79	38	hybridization	hybridization	NOUN
ajst-32245	79	39	,	,	PUNCT
ajst-32245	79	40	or	or	CCONJ
ajst-32245	79	41	protein	protein	NOUN
ajst-32245	79	42	recognition	recognition	NOUN
ajst-32245	79	43	,	,	PUNCT
ajst-32245	79	44	thereby	thereby	ADV
ajst-32245	79	45	allowing	allow	VERB
ajst-32245	79	46	both	both	CCONJ
ajst-32245	79	47	qualitative	qualitative	ADJ
ajst-32245	79	48	and	and	CCONJ
ajst-32245	79	49	quantitative	quantitative	ADJ
ajst-32245	79	50	analysis	analysis	NOUN
ajst-32245	79	51	of	of	ADP
ajst-32245	79	52	target	target	NOUN
ajst-32245	79	53	biomolecules	biomolecule	NOUN
ajst-32245	79	54	.	.	PUNCT
ajst-32245	80	1	a	a	DET
ajst-32245	80	2	schematic	schematic	ADJ
ajst-32245	80	3	of	of	ADP
ajst-32245	80	4	the	the	DET
ajst-32245	80	5	spr	spr	PROPN
ajst-32245	80	6	principle	principle	NOUN
ajst-32245	80	7	is	be	AUX
ajst-32245	80	8	shown	show	VERB
ajst-32245	80	9	below	below	ADV
ajst-32245	80	10	.	.	PUNCT
ajst-32245	81	1	figure	figure	NOUN
ajst-32245	81	2	2	2	NUM
ajst-32245	81	3	.	.	PUNCT
ajst-32245	81	4	molecular	molecular	ADJ
ajst-32245	81	5	mechanism	mechanism	NOUN
ajst-32245	81	6	of	of	ADP
ajst-32245	81	7	spr	spr	ADJ
ajst-32245	81	8	sensor	sensor	NOUN
ajst-32245	81	9	spr	spr	PROPN
ajst-32245	81	10	technology	technology	NOUN
ajst-32245	81	11	has	have	AUX
ajst-32245	81	12	attracted	attract	VERB
ajst-32245	81	13	considerable	considerable	ADJ
ajst-32245	81	14	attention	attention	NOUN
ajst-32245	81	15	in	in	ADP
ajst-32245	81	16	biosensing	biosense	VERB
ajst-32245	81	17	due	due	ADP
ajst-32245	81	18	to	to	ADP
ajst-32245	81	19	its	its	PRON
ajst-32245	81	20	label	label	NOUN
ajst-32245	81	21	-	-	PUNCT
ajst-32245	81	22	free	free	ADJ
ajst-32245	81	23	,	,	PUNCT
ajst-32245	81	24	real	real	ADJ
ajst-32245	81	25	-	-	PUNCT
ajst-32245	81	26	time	time	NOUN
ajst-32245	81	27	,	,	PUNCT
ajst-32245	81	28	and	and	CCONJ
ajst-32245	81	29	highly	highly	ADV
ajst-32245	81	30	sensitive	sensitive	ADJ
ajst-32245	81	31	characteristics	characteristic	NOUN
ajst-32245	81	32	[	[	X
ajst-32245	81	33	27	27	NUM
ajst-32245	81	34	]	]	PUNCT
ajst-32245	81	35	.	.	PUNCT
ajst-32245	82	1	although	although	SCONJ
ajst-32245	82	2	relatively	relatively	ADV
ajst-32245	82	3	few	few	ADJ
ajst-32245	82	4	reports	report	NOUN
ajst-32245	82	5	directly	directly	ADV
ajst-32245	82	6	describe	describe	VERB
ajst-32245	82	7	spr	spr	ADV
ajst-32245	82	8	-	-	PUNCT
ajst-32245	82	9	based	base	VERB
ajst-32245	82	10	optical	optical	ADJ
ajst-32245	82	11	sensors	sensor	NOUN
ajst-32245	82	12	for	for	ADP
ajst-32245	82	13	ad	ad	NOUN
ajst-32245	82	14	,	,	PUNCT
ajst-32245	82	15	the	the	DET
ajst-32245	82	16	technique	technique	NOUN
ajst-32245	82	17	has	have	AUX
ajst-32245	82	18	demonstrated	demonstrate	VERB
ajst-32245	82	19	significant	significant	ADJ
ajst-32245	82	20	potential	potential	NOUN
ajst-32245	82	21	in	in	ADP
ajst-32245	82	22	cancer	cancer	NOUN
ajst-32245	82	23	cell	cell	NOUN
ajst-32245	82	24	detection	detection	NOUN
ajst-32245	82	25	.	.	PUNCT
ajst-32245	83	1	for	for	ADP
ajst-32245	83	2	instance	instance	NOUN
ajst-32245	83	3	,	,	PUNCT
ajst-32245	83	4	cancer	cancer	NOUN
ajst-32245	83	5	cells	cell	NOUN
ajst-32245	83	6	can	can	AUX
ajst-32245	83	7	be	be	AUX
ajst-32245	83	8	identified	identify	VERB
ajst-32245	83	9	by	by	ADP
ajst-32245	83	10	monitoring	monitor	VERB
ajst-32245	83	11	shifts	shift	NOUN
ajst-32245	83	12	in	in	ADP
ajst-32245	83	13	the	the	DET
ajst-32245	83	14	resonance	resonance	NOUN
ajst-32245	83	15	wavelength	wavelength	NOUN
ajst-32245	83	16	[	[	X
ajst-32245	83	17	28	28	NUM
ajst-32245	83	18	]	]	PUNCT
ajst-32245	83	19	.	.	PUNCT
ajst-32245	84	1	this	this	DET
ajst-32245	84	2	principle	principle	NOUN
ajst-32245	84	3	applies	apply	VERB
ajst-32245	84	4	equally	equally	ADV
ajst-32245	84	5	to	to	ADP
ajst-32245	84	6	the	the	DET
ajst-32245	84	7	binding	bind	VERB
ajst-32245	84	8	interactions	interaction	NOUN
ajst-32245	84	9	between	between	ADP
ajst-32245	84	10	ad	ad	NOUN
ajst-32245	84	11	biomarkers	biomarker	NOUN
ajst-32245	84	12	and	and	CCONJ
ajst-32245	84	13	their	their	PRON
ajst-32245	84	14	corresponding	corresponding	ADJ
ajst-32245	84	15	receptors	receptor	NOUN
ajst-32245	84	16	.	.	PUNCT
ajst-32245	85	1	2.2.3	2.2.3	NUM
ajst-32245	85	2	optical	optical	ADJ
ajst-32245	85	3	coherence	coherence	NOUN
ajst-32245	85	4	tomography	tomography	NOUN
ajst-32245	85	5	(	(	PUNCT
ajst-32245	85	6	oct	oct	PROPN
ajst-32245	85	7	)	)	PUNCT
ajst-32245	85	8	and	and	CCONJ
ajst-32245	85	9	oct	oct	PROPN
ajst-32245	85	10	angiography	angiography	NOUN
ajst-32245	85	11	(	(	PUNCT
ajst-32245	85	12	octa	octa	NOUN
ajst-32245	85	13	)	)	PUNCT
ajst-32245	85	14	optical	optical	ADJ
ajst-32245	85	15	coherence	coherence	NOUN
ajst-32245	85	16	tomography	tomography	NOUN
ajst-32245	85	17	(	(	PUNCT
ajst-32245	85	18	oct	oct	PROPN
ajst-32245	85	19	)	)	PUNCT
ajst-32245	85	20	is	be	AUX
ajst-32245	85	21	an	an	DET
ajst-32245	85	22	imaging	imaging	NOUN
ajst-32245	85	23	technique	technique	NOUN
ajst-32245	85	24	based	base	VERB
ajst-32245	85	25	on	on	ADP
ajst-32245	85	26	the	the	DET
ajst-32245	85	27	principle	principle	NOUN
ajst-32245	85	28	of	of	ADP
ajst-32245	85	29	lowcoherence	lowcoherence	NOUN
ajst-32245	85	30	interferometry	interferometry	NOUN
ajst-32245	85	31	.	.	PUNCT
ajst-32245	86	1	by	by	ADP
ajst-32245	86	2	measuring	measure	VERB
ajst-32245	86	3	the	the	DET
ajst-32245	86	4	time	time	NOUN
ajst-32245	86	5	delay	delay	NOUN
ajst-32245	86	6	and	and	CCONJ
ajst-32245	86	7	intensity	intensity	NOUN
ajst-32245	86	8	variations	variation	NOUN
ajst-32245	86	9	of	of	ADP
ajst-32245	86	10	reflected	reflect	VERB
ajst-32245	86	11	or	or	CCONJ
ajst-32245	86	12	scattered	scatter	VERB
ajst-32245	86	13	light	light	NOUN
ajst-32245	86	14	at	at	ADP
ajst-32245	86	15	different	different	ADJ
ajst-32245	86	16	depths	depth	NOUN
ajst-32245	86	17	within	within	ADP
ajst-32245	86	18	a	a	DET
ajst-32245	86	19	sample	sample	NOUN
ajst-32245	86	20	,	,	PUNCT
ajst-32245	86	21	oct	oct	PROPN
ajst-32245	86	22	reconstructs	reconstruct	VERB
ajst-32245	86	23	high	high	ADJ
ajst-32245	86	24	-	-	PUNCT
ajst-32245	86	25	resolution	resolution	NOUN
ajst-32245	86	26	cross	cross	ADJ
ajst-32245	86	27	-	-	ADJ
ajst-32245	86	28	sectional	sectional	ADJ
ajst-32245	86	29	28	28	NUM
ajst-32245	86	30	images	image	NOUN
ajst-32245	86	31	of	of	ADP
ajst-32245	86	32	tissues	tissue	NOUN
ajst-32245	86	33	,	,	PUNCT
ajst-32245	86	34	enabling	enable	VERB
ajst-32245	86	35	non	non	ADJ
ajst-32245	86	36	-	-	ADJ
ajst-32245	86	37	invasive	invasive	ADJ
ajst-32245	86	38	visualization	visualization	NOUN
ajst-32245	86	39	of	of	ADP
ajst-32245	86	40	microscopic	microscopic	ADJ
ajst-32245	86	41	biological	biological	ADJ
ajst-32245	86	42	structures	structure	NOUN
ajst-32245	86	43	.	.	PUNCT
ajst-32245	87	1	the	the	DET
ajst-32245	87	2	underlying	underlying	ADJ
ajst-32245	87	3	principle	principle	NOUN
ajst-32245	87	4	is	be	AUX
ajst-32245	87	5	illustrated	illustrate	VERB
ajst-32245	87	6	in	in	ADP
ajst-32245	87	7	the	the	DET
ajst-32245	87	8	schematic	schematic	ADJ
ajst-32245	87	9	below	below	NOUN
ajst-32245	87	10	.	.	PUNCT
ajst-32245	88	1	figure	figure	VERB
ajst-32245	88	2	3	3	NUM
ajst-32245	88	3	.	.	PUNCT
ajst-32245	89	1	how	how	SCONJ
ajst-32245	89	2	oct	oct	NOUN
ajst-32245	89	3	biosensor	biosensor	NOUN
ajst-32245	89	4	works	work	VERB
ajst-32245	89	5	these	these	DET
ajst-32245	89	6	two	two	NUM
ajst-32245	89	7	non	non	ADJ
ajst-32245	89	8	-	-	ADJ
ajst-32245	89	9	invasive	invasive	ADJ
ajst-32245	89	10	imaging	imaging	NOUN
ajst-32245	89	11	techniques	technique	NOUN
ajst-32245	89	12	are	be	AUX
ajst-32245	89	13	potential	potential	ADJ
ajst-32245	89	14	tools	tool	NOUN
ajst-32245	89	15	for	for	ADP
ajst-32245	89	16	early	early	ADJ
ajst-32245	89	17	ad	ad	NOUN
ajst-32245	89	18	diagnosis	diagnosis	NOUN
ajst-32245	89	19	[	[	X
ajst-32245	89	20	29	29	NUM
ajst-32245	89	21	,	,	PUNCT
ajst-32245	89	22	30	30	NUM
ajst-32245	89	23	]	]	PUNCT
ajst-32245	89	24	.	.	PUNCT
ajst-32245	90	1	changes	change	NOUN
ajst-32245	90	2	in	in	ADP
ajst-32245	90	3	retinal	retinal	ADJ
ajst-32245	90	4	vascular	vascular	ADJ
ajst-32245	90	5	density	density	NOUN
ajst-32245	90	6	and	and	CCONJ
ajst-32245	90	7	the	the	DET
ajst-32245	90	8	foveal	foveal	ADJ
ajst-32245	90	9	avascular	avascular	ADJ
ajst-32245	90	10	zone	zone	NOUN
ajst-32245	90	11	(	(	PUNCT
ajst-32245	90	12	faz	faz	PROPN
ajst-32245	90	13	)	)	PUNCT
ajst-32245	90	14	may	may	AUX
ajst-32245	90	15	serve	serve	VERB
ajst-32245	90	16	as	as	ADP
ajst-32245	90	17	potential	potential	ADJ
ajst-32245	90	18	ocular	ocular	ADJ
ajst-32245	90	19	biomarkers	biomarker	NOUN
ajst-32245	90	20	for	for	ADP
ajst-32245	90	21	ad	ad	NOUN
ajst-32245	90	22	[	[	X
ajst-32245	90	23	29	29	NUM
ajst-32245	90	24	]	]	PUNCT
ajst-32245	90	25	.	.	PUNCT
ajst-32245	91	1	although	although	SCONJ
ajst-32245	91	2	these	these	DET
ajst-32245	91	3	techniques	technique	NOUN
ajst-32245	91	4	are	be	AUX
ajst-32245	91	5	imaging	imaging	NOUN
ajst-32245	91	6	-	-	PUNCT
ajst-32245	91	7	based	base	VERB
ajst-32245	91	8	rather	rather	ADV
ajst-32245	91	9	than	than	ADP
ajst-32245	91	10	conventional	conventional	ADJ
ajst-32245	91	11	biosensors	biosensor	NOUN
ajst-32245	91	12	,	,	PUNCT
ajst-32245	91	13	they	they	PRON
ajst-32245	91	14	exploit	exploit	VERB
ajst-32245	91	15	optical	optical	ADJ
ajst-32245	91	16	principles	principle	NOUN
ajst-32245	91	17	to	to	PART
ajst-32245	91	18	capture	capture	VERB
ajst-32245	91	19	microscopic	microscopic	ADJ
ajst-32245	91	20	alterations	alteration	NOUN
ajst-32245	91	21	within	within	ADP
ajst-32245	91	22	biological	biological	ADJ
ajst-32245	91	23	tissues	tissue	NOUN
ajst-32245	91	24	,	,	PUNCT
ajst-32245	91	25	providing	provide	VERB
ajst-32245	91	26	valuable	valuable	ADJ
ajst-32245	91	27	insights	insight	NOUN
ajst-32245	91	28	for	for	ADP
ajst-32245	91	29	early	early	ADJ
ajst-32245	91	30	optical	optical	ADJ
ajst-32245	91	31	diagnosis	diagnosis	NOUN
ajst-32245	91	32	of	of	ADP
ajst-32245	91	33	ad	ad	NOUN
ajst-32245	91	34	.	.	PUNCT
ajst-32245	92	1	despite	despite	SCONJ
ajst-32245	92	2	the	the	DET
ajst-32245	92	3	considerable	considerable	ADJ
ajst-32245	92	4	promise	promise	NOUN
ajst-32245	92	5	of	of	ADP
ajst-32245	92	6	optical	optical	ADJ
ajst-32245	92	7	biosensors	biosensor	NOUN
ajst-32245	92	8	for	for	ADP
ajst-32245	92	9	the	the	DET
ajst-32245	92	10	early	early	ADJ
ajst-32245	92	11	detection	detection	NOUN
ajst-32245	92	12	of	of	ADP
ajst-32245	92	13	alzheimer	alzheimer	PROPN
ajst-32245	92	14	’s	’s	PART
ajst-32245	92	15	disease	disease	NOUN
ajst-32245	92	16	(	(	PUNCT
ajst-32245	92	17	ad	ad	NOUN
ajst-32245	92	18	)	)	PUNCT
ajst-32245	92	19	,	,	PUNCT
ajst-32245	92	20	several	several	ADJ
ajst-32245	92	21	significant	significant	ADJ
ajst-32245	92	22	challenges	challenge	NOUN
ajst-32245	92	23	remain	remain	VERB
ajst-32245	92	24	to	to	PART
ajst-32245	92	25	be	be	AUX
ajst-32245	92	26	addressed	address	VERB
ajst-32245	92	27	.	.	PUNCT
ajst-32245	93	1	one	one	NUM
ajst-32245	93	2	of	of	ADP
ajst-32245	93	3	the	the	DET
ajst-32245	93	4	most	most	ADV
ajst-32245	93	5	pressing	pressing	ADJ
ajst-32245	93	6	issues	issue	NOUN
ajst-32245	93	7	is	be	AUX
ajst-32245	93	8	sensitivity	sensitivity	NOUN
ajst-32245	93	9	and	and	CCONJ
ajst-32245	93	10	specificity	specificity	NOUN
ajst-32245	93	11	.	.	PUNCT
ajst-32245	94	1	in	in	ADP
ajst-32245	94	2	complex	complex	ADJ
ajst-32245	94	3	biological	biological	ADJ
ajst-32245	94	4	samples	sample	NOUN
ajst-32245	94	5	such	such	ADJ
ajst-32245	94	6	as	as	ADP
ajst-32245	94	7	blood	blood	NOUN
ajst-32245	94	8	,	,	PUNCT
ajst-32245	94	9	biomarker	biomarker	NOUN
ajst-32245	94	10	concentrations	concentration	NOUN
ajst-32245	94	11	are	be	AUX
ajst-32245	94	12	generally	generally	ADV
ajst-32245	94	13	very	very	ADV
ajst-32245	94	14	low	low	ADJ
ajst-32245	94	15	and	and	CCONJ
ajst-32245	94	16	accompanied	accompany	VERB
ajst-32245	94	17	by	by	ADP
ajst-32245	94	18	numerous	numerous	ADJ
ajst-32245	94	19	interfering	interfering	ADJ
ajst-32245	94	20	substances	substance	NOUN
ajst-32245	94	21	,	,	PUNCT
ajst-32245	94	22	necessitating	necessitate	VERB
ajst-32245	94	23	extremely	extremely	ADV
ajst-32245	94	24	high	high	ADJ
ajst-32245	94	25	analytical	analytical	ADJ
ajst-32245	94	26	precision	precision	NOUN
ajst-32245	94	27	levels	level	NOUN
ajst-32245	94	28	[	[	X
ajst-32245	94	29	31	31	NUM
ajst-32245	94	30	]	]	PUNCT
ajst-32245	94	31	.	.	PUNCT
ajst-32245	95	1	to	to	PART
ajst-32245	95	2	overcome	overcome	VERB
ajst-32245	95	3	this	this	DET
ajst-32245	95	4	barrier	barrier	NOUN
ajst-32245	95	5	,	,	PUNCT
ajst-32245	95	6	future	future	ADJ
ajst-32245	95	7	research	research	NOUN
ajst-32245	95	8	should	should	AUX
ajst-32245	95	9	prioritize	prioritize	VERB
ajst-32245	95	10	the	the	DET
ajst-32245	95	11	development	development	NOUN
ajst-32245	95	12	of	of	ADP
ajst-32245	95	13	novel	novel	ADJ
ajst-32245	95	14	nanomaterials	nanomaterial	NOUN
ajst-32245	95	15	and	and	CCONJ
ajst-32245	95	16	innovative	innovative	ADJ
ajst-32245	95	17	sensing	sense	VERB
ajst-32245	95	18	mechanisms	mechanism	NOUN
ajst-32245	95	19	that	that	PRON
ajst-32245	95	20	can	can	AUX
ajst-32245	95	21	enhance	enhance	VERB
ajst-32245	95	22	detection	detection	NOUN
ajst-32245	95	23	performance	performance	NOUN
ajst-32245	95	24	and	and	CCONJ
ajst-32245	95	25	reliability	reliability	NOUN
ajst-32245	95	26	.	.	PUNCT
ajst-32245	96	1	another	another	DET
ajst-32245	96	2	major	major	ADJ
ajst-32245	96	3	limitation	limitation	NOUN
ajst-32245	96	4	is	be	AUX
ajst-32245	96	5	the	the	DET
ajst-32245	96	6	lack	lack	NOUN
ajst-32245	96	7	of	of	ADP
ajst-32245	96	8	standardization	standardization	NOUN
ajst-32245	96	9	and	and	CCONJ
ajst-32245	96	10	clinical	clinical	ADJ
ajst-32245	96	11	translation	translation	NOUN
ajst-32245	96	12	.	.	PUNCT
ajst-32245	97	1	most	most	ADJ
ajst-32245	97	2	optical	optical	ADJ
ajst-32245	97	3	biosensors	biosensor	NOUN
ajst-32245	97	4	remain	remain	VERB
ajst-32245	97	5	at	at	ADP
ajst-32245	97	6	the	the	DET
ajst-32245	97	7	laboratory	laboratory	NOUN
ajst-32245	97	8	-	-	PUNCT
ajst-32245	97	9	based	base	VERB
ajst-32245	97	10	research	research	NOUN
ajst-32245	97	11	stage	stage	NOUN
ajst-32245	97	12	,	,	PUNCT
ajst-32245	97	13	with	with	ADP
ajst-32245	97	14	few	few	ADJ
ajst-32245	97	15	undergoing	undergo	VERB
ajst-32245	97	16	rigorous	rigorous	ADJ
ajst-32245	97	17	large	large	ADJ
ajst-32245	97	18	-	-	PUNCT
ajst-32245	97	19	scale	scale	NOUN
ajst-32245	97	20	clinical	clinical	ADJ
ajst-32245	97	21	validation	validation	NOUN
ajst-32245	97	22	.	.	PUNCT
ajst-32245	98	1	transitioning	transition	VERB
ajst-32245	98	2	these	these	DET
ajst-32245	98	3	technologies	technology	NOUN
ajst-32245	98	4	from	from	ADP
ajst-32245	98	5	bench	bench	NOUN
ajst-32245	98	6	to	to	ADP
ajst-32245	98	7	bedside	bedside	NOUN
ajst-32245	98	8	requires	require	VERB
ajst-32245	98	9	addressing	address	VERB
ajst-32245	98	10	regulatory	regulatory	ADJ
ajst-32245	98	11	hurdles	hurdle	NOUN
ajst-32245	98	12	,	,	PUNCT
ajst-32245	98	13	production	production	NOUN
ajst-32245	98	14	costs	cost	NOUN
ajst-32245	98	15	,	,	PUNCT
ajst-32245	98	16	and	and	CCONJ
ajst-32245	98	17	usability	usability	NOUN
ajst-32245	98	18	challenges	challenge	NOUN
ajst-32245	98	19	,	,	PUNCT
ajst-32245	98	20	which	which	PRON
ajst-32245	98	21	are	be	AUX
ajst-32245	98	22	critical	critical	ADJ
ajst-32245	98	23	for	for	ADP
ajst-32245	98	24	achieving	achieve	VERB
ajst-32245	98	25	widespread	widespread	ADJ
ajst-32245	98	26	clinical	clinical	ADJ
ajst-32245	98	27	adoption	adoption	NOUN
ajst-32245	98	28	.	.	PUNCT
ajst-32245	99	1	in	in	ADP
ajst-32245	99	2	addition	addition	NOUN
ajst-32245	99	3	,	,	PUNCT
ajst-32245	99	4	given	give	VERB
ajst-32245	99	5	ad	ad	NOUN
ajst-32245	99	6	's	's	PART
ajst-32245	99	7	multifactorial	multifactorial	ADJ
ajst-32245	99	8	nature	nature	NOUN
ajst-32245	99	9	,	,	PUNCT
ajst-32245	99	10	it	it	PRON
ajst-32245	99	11	is	be	AUX
ajst-32245	99	12	essential	essential	ADJ
ajst-32245	99	13	to	to	PART
ajst-32245	99	14	pursue	pursue	VERB
ajst-32245	99	15	multiparametric	multiparametric	ADJ
ajst-32245	99	16	integration	integration	NOUN
ajst-32245	99	17	in	in	ADP
ajst-32245	99	18	optical	optical	ADJ
ajst-32245	99	19	biosensor	biosensor	NOUN
ajst-32245	99	20	design	design	NOUN
ajst-32245	99	21	.	.	PUNCT
ajst-32245	100	1	ad	ad	NOUN
ajst-32245	100	2	involves	involve	VERB
ajst-32245	100	3	complex	complex	ADJ
ajst-32245	100	4	interactions	interaction	NOUN
ajst-32245	100	5	among	among	ADP
ajst-32245	100	6	genetic	genetic	ADJ
ajst-32245	100	7	,	,	PUNCT
ajst-32245	100	8	environmental	environmental	ADJ
ajst-32245	100	9	,	,	PUNCT
ajst-32245	100	10	and	and	CCONJ
ajst-32245	100	11	lifestyle	lifestyle	NOUN
ajst-32245	100	12	factors	factor	NOUN
ajst-32245	100	13	.	.	PUNCT
ajst-32245	101	1	therefore	therefore	ADV
ajst-32245	101	2	,	,	PUNCT
ajst-32245	101	3	future	future	ADJ
ajst-32245	101	4	biosensors	biosensor	NOUN
ajst-32245	101	5	should	should	AUX
ajst-32245	101	6	be	be	AUX
ajst-32245	101	7	capable	capable	ADJ
ajst-32245	101	8	of	of	ADP
ajst-32245	101	9	simultaneously	simultaneously	ADV
ajst-32245	101	10	detecting	detect	VERB
ajst-32245	101	11	multiple	multiple	ADJ
ajst-32245	101	12	biomarkers	biomarker	NOUN
ajst-32245	101	13	while	while	SCONJ
ajst-32245	101	14	incorporating	incorporate	VERB
ajst-32245	101	15	broader	broad	ADJ
ajst-32245	101	16	datasets	dataset	NOUN
ajst-32245	101	17	to	to	PART
ajst-32245	101	18	establish	establish	VERB
ajst-32245	101	19	more	more	ADV
ajst-32245	101	20	comprehensive	comprehensive	ADJ
ajst-32245	101	21	diagnostic	diagnostic	ADJ
ajst-32245	101	22	models	model	NOUN
ajst-32245	101	23	.	.	PUNCT
ajst-32245	102	1	finally	finally	ADV
ajst-32245	102	2	,	,	PUNCT
ajst-32245	102	3	integrating	integrate	VERB
ajst-32245	102	4	optical	optical	ADJ
ajst-32245	102	5	biosensors	biosensor	NOUN
ajst-32245	102	6	with	with	ADP
ajst-32245	102	7	microfluidic	microfluidic	ADJ
ajst-32245	102	8	technology	technology	NOUN
ajst-32245	102	9	offers	offer	VERB
ajst-32245	102	10	another	another	DET
ajst-32245	102	11	promising	promising	ADJ
ajst-32245	102	12	direction	direction	NOUN
ajst-32245	102	13	.	.	PUNCT
ajst-32245	103	1	by	by	ADP
ajst-32245	103	2	combining	combine	VERB
ajst-32245	103	3	sample	sample	NOUN
ajst-32245	103	4	processing	processing	NOUN
ajst-32245	103	5	,	,	PUNCT
ajst-32245	103	6	biochemical	biochemical	ADJ
ajst-32245	103	7	reactions	reaction	NOUN
ajst-32245	103	8	,	,	PUNCT
ajst-32245	103	9	and	and	CCONJ
ajst-32245	103	10	detection	detection	NOUN
ajst-32245	103	11	within	within	ADP
ajst-32245	103	12	a	a	DET
ajst-32245	103	13	single	single	ADJ
ajst-32245	103	14	miniaturized	miniaturize	VERB
ajst-32245	103	15	platform	platform	NOUN
ajst-32245	103	16	,	,	PUNCT
ajst-32245	103	17	microfluidic	microfluidic	ADJ
ajst-32245	103	18	-	-	PUNCT
ajst-32245	103	19	assisted	assist	VERB
ajst-32245	103	20	optical	optical	ADJ
ajst-32245	103	21	biosensors	biosensor	NOUN
ajst-32245	103	22	could	could	AUX
ajst-32245	103	23	facilitate	facilitate	VERB
ajst-32245	103	24	point	point	NOUN
ajst-32245	103	25	-	-	PUNCT
ajst-32245	103	26	of	of	ADP
ajst-32245	103	27	-	-	PUNCT
ajst-32245	103	28	care	care	NOUN
ajst-32245	103	29	testing	testing	NOUN
ajst-32245	103	30	(	(	PUNCT
ajst-32245	103	31	poct	poct	PROPN
ajst-32245	103	32	)	)	PUNCT
ajst-32245	103	33	,	,	PUNCT
ajst-32245	103	34	making	make	VERB
ajst-32245	103	35	early	early	ADJ
ajst-32245	103	36	ad	ad	NOUN
ajst-32245	103	37	diagnostics	diagnostic	NOUN
ajst-32245	103	38	more	more	ADV
ajst-32245	103	39	accessible	accessible	ADJ
ajst-32245	103	40	,	,	PUNCT
ajst-32245	103	41	rapid	rapid	ADJ
ajst-32245	103	42	,	,	PUNCT
ajst-32245	103	43	and	and	CCONJ
ajst-32245	103	44	user	user	NOUN
ajst-32245	103	45	-	-	PUNCT
ajst-32245	103	46	friendly	friendly	ADJ
ajst-32245	103	47	[	[	X
ajst-32245	103	48	32	32	NUM
ajst-32245	103	49	]	]	PUNCT
ajst-32245	103	50	.	.	PUNCT
ajst-32245	104	1	addressing	address	VERB
ajst-32245	104	2	these	these	DET
ajst-32245	104	3	challenges	challenge	NOUN
ajst-32245	104	4	will	will	AUX
ajst-32245	104	5	be	be	AUX
ajst-32245	104	6	essential	essential	ADJ
ajst-32245	104	7	for	for	ADP
ajst-32245	104	8	advancing	advance	VERB
ajst-32245	104	9	optical	optical	ADJ
ajst-32245	104	10	biosensors	biosensor	NOUN
ajst-32245	104	11	from	from	ADP
ajst-32245	104	12	experimental	experimental	ADJ
ajst-32245	104	13	prototypes	prototype	NOUN
ajst-32245	104	14	to	to	ADP
ajst-32245	104	15	practical	practical	ADJ
ajst-32245	104	16	and	and	CCONJ
ajst-32245	104	17	clinically	clinically	ADV
ajst-32245	104	18	relevant	relevant	ADJ
ajst-32245	104	19	diagnostic	diagnostic	ADJ
ajst-32245	104	20	tools	tool	NOUN
ajst-32245	104	21	,	,	PUNCT
ajst-32245	104	22	ultimately	ultimately	ADV
ajst-32245	104	23	contributing	contribute	VERB
ajst-32245	104	24	to	to	ADP
ajst-32245	104	25	more	more	ADV
ajst-32245	104	26	accurate	accurate	ADJ
ajst-32245	104	27	and	and	CCONJ
ajst-32245	104	28	accessible	accessible	ADJ
ajst-32245	104	29	early	early	ADJ
ajst-32245	104	30	ad	ad	NOUN
ajst-32245	104	31	detection	detection	NOUN
ajst-32245	104	32	.	.	PUNCT
ajst-32245	105	1	29	29	NUM
ajst-32245	105	2	3	3	NUM
ajst-32245	105	3	.	.	PUNCT
ajst-32245	105	4	conclusion	conclusion	NOUN
ajst-32245	105	5	this	this	DET
ajst-32245	105	6	review	review	NOUN
ajst-32245	105	7	comprehensively	comprehensively	ADV
ajst-32245	105	8	summarizes	summarize	VERB
ajst-32245	105	9	the	the	DET
ajst-32245	105	10	latest	late	ADJ
ajst-32245	105	11	advances	advance	NOUN
ajst-32245	105	12	in	in	ADP
ajst-32245	105	13	biosensor	biosensor	NOUN
ajst-32245	105	14	applications	application	NOUN
ajst-32245	105	15	for	for	ADP
ajst-32245	105	16	alzheimer	alzheimer	PROPN
ajst-32245	105	17	’s	’s	PART
ajst-32245	105	18	disease	disease	NOUN
ajst-32245	105	19	(	(	PUNCT
ajst-32245	105	20	ad	ad	NOUN
ajst-32245	105	21	)	)	PUNCT
ajst-32245	105	22	diagnosis	diagnosis	NOUN
ajst-32245	105	23	and	and	CCONJ
ajst-32245	105	24	daily	daily	ADJ
ajst-32245	105	25	care	care	NOUN
ajst-32245	105	26	over	over	ADP
ajst-32245	105	27	the	the	DET
ajst-32245	105	28	past	past	ADJ
ajst-32245	105	29	five	five	NUM
ajst-32245	105	30	years	year	NOUN
ajst-32245	105	31	(	(	PUNCT
ajst-32245	105	32	2020–2025	2020–2025	NUM
ajst-32245	105	33	)	)	PUNCT
ajst-32245	105	34	.	.	PUNCT
ajst-32245	106	1	studies	study	NOUN
ajst-32245	106	2	indicate	indicate	VERB
ajst-32245	106	3	that	that	SCONJ
ajst-32245	106	4	biosensor	biosensor	NOUN
ajst-32245	106	5	technologies	technology	NOUN
ajst-32245	106	6	,	,	PUNCT
ajst-32245	106	7	particularly	particularly	ADV
ajst-32245	106	8	electrochemical	electrochemical	ADJ
ajst-32245	106	9	and	and	CCONJ
ajst-32245	106	10	optical	optical	ADJ
ajst-32245	106	11	biosensors	biosensor	NOUN
ajst-32245	106	12	,	,	PUNCT
ajst-32245	106	13	offer	offer	VERB
ajst-32245	106	14	great	great	ADJ
ajst-32245	106	15	potential	potential	NOUN
ajst-32245	106	16	for	for	ADP
ajst-32245	106	17	early	early	ADJ
ajst-32245	106	18	,	,	PUNCT
ajst-32245	106	19	rapid	rapid	ADJ
ajst-32245	106	20	,	,	PUNCT
ajst-32245	106	21	non	non	ADJ
ajst-32245	106	22	-	-	ADJ
ajst-32245	106	23	invasive	invasive	ADJ
ajst-32245	106	24	or	or	CCONJ
ajst-32245	106	25	minimally	minimally	ADV
ajst-32245	106	26	invasive	invasive	ADJ
ajst-32245	106	27	ad	ad	NOUN
ajst-32245	106	28	diagnosis	diagnosis	NOUN
ajst-32245	106	29	by	by	ADP
ajst-32245	106	30	enabling	enable	VERB
ajst-32245	106	31	highly	highly	ADV
ajst-32245	106	32	sensitive	sensitive	ADJ
ajst-32245	106	33	detection	detection	NOUN
ajst-32245	106	34	of	of	ADP
ajst-32245	106	35	specific	specific	ADJ
ajst-32245	106	36	biomarkers	biomarker	NOUN
ajst-32245	106	37	such	such	ADJ
ajst-32245	106	38	as	as	ADP
ajst-32245	106	39	β	β	NOUN
ajst-32245	106	40	-	-	NOUN
ajst-32245	106	41	amyloid	amyloid	NOUN
ajst-32245	106	42	(	(	PUNCT
ajst-32245	106	43	aβ	aβ	NOUN
ajst-32245	106	44	)	)	PUNCT
ajst-32245	106	45	,	,	PUNCT
ajst-32245	106	46	tau	tau	PROPN
ajst-32245	106	47	protein	protein	NOUN
ajst-32245	106	48	,	,	PUNCT
ajst-32245	106	49	and	and	CCONJ
ajst-32245	106	50	exosomal	exosomal	ADJ
ajst-32245	106	51	mirnas	mirna	NOUN
ajst-32245	106	52	.	.	PUNCT
ajst-32245	107	1	combined	combined	ADJ
ajst-32245	107	2	detection	detection	NOUN
ajst-32245	107	3	strategies	strategy	NOUN
ajst-32245	107	4	targeting	target	VERB
ajst-32245	107	5	multiple	multiple	ADJ
ajst-32245	107	6	biomarkers	biomarker	NOUN
ajst-32245	107	7	—	—	PUNCT
ajst-32245	107	8	for	for	ADP
ajst-32245	107	9	instance	instance	NOUN
ajst-32245	107	10	,	,	PUNCT
ajst-32245	107	11	electrochemical	electrochemical	ADJ
ajst-32245	107	12	biosensors	biosensor	NOUN
ajst-32245	107	13	based	base	VERB
ajst-32245	107	14	on	on	ADP
ajst-32245	107	15	vertical	vertical	ADJ
ajst-32245	107	16	graphene	graphene	NOUN
ajst-32245	107	17	simultaneously	simultaneously	ADV
ajst-32245	107	18	detecting	detect	VERB
ajst-32245	107	19	four	four	NUM
ajst-32245	107	20	plasma	plasma	NOUN
ajst-32245	107	21	ad	ad	NOUN
ajst-32245	107	22	biomarkers	biomarker	NOUN
ajst-32245	107	23	—	—	PUNCT
ajst-32245	107	24	significantly	significantly	ADV
ajst-32245	107	25	enhance	enhance	VERB
ajst-32245	107	26	diagnostic	diagnostic	ADJ
ajst-32245	107	27	accuracy	accuracy	NOUN
ajst-32245	107	28	.	.	PUNCT
ajst-32245	108	1	despite	despite	SCONJ
ajst-32245	108	2	remaining	remain	VERB
ajst-32245	108	3	challenges	challenge	NOUN
ajst-32245	108	4	—	—	PUNCT
ajst-32245	108	5	such	such	ADJ
ajst-32245	108	6	as	as	ADP
ajst-32245	108	7	further	far	ADV
ajst-32245	108	8	enhancing	enhance	VERB
ajst-32245	108	9	sensor	sensor	NOUN
ajst-32245	108	10	sensitivity	sensitivity	NOUN
ajst-32245	108	11	and	and	CCONJ
ajst-32245	108	12	specificity	specificity	NOUN
ajst-32245	108	13	in	in	ADP
ajst-32245	108	14	complex	complex	ADJ
ajst-32245	108	15	biological	biological	ADJ
ajst-32245	108	16	samples	sample	NOUN
ajst-32245	108	17	and	and	CCONJ
ajst-32245	108	18	effectively	effectively	ADV
ajst-32245	108	19	translating	translate	VERB
ajst-32245	108	20	laboratory	laboratory	NOUN
ajst-32245	108	21	findings	finding	NOUN
ajst-32245	108	22	into	into	ADP
ajst-32245	108	23	clinical	clinical	ADJ
ajst-32245	108	24	practice	practice	NOUN
ajst-32245	108	25	—	—	PUNCT
ajst-32245	108	26	the	the	DET
ajst-32245	108	27	field	field	NOUN
ajst-32245	108	28	's	's	PART
ajst-32245	108	29	future	future	ADJ
ajst-32245	108	30	direction	direction	NOUN
ajst-32245	108	31	is	be	AUX
ajst-32245	108	32	clear	clear	ADJ
ajst-32245	108	33	.	.	PUNCT
ajst-32245	109	1	multimodal	multimodal	ADJ
ajst-32245	109	2	sensing	sense	VERB
ajst-32245	109	3	platforms	platform	NOUN
ajst-32245	109	4	,	,	PUNCT
ajst-32245	109	5	in	in	ADP
ajst-32245	109	6	-	-	PUNCT
ajst-32245	109	7	depth	depth	NOUN
ajst-32245	109	8	liquid	liquid	ADJ
ajst-32245	109	9	biopsy	biopsy	NOUN
ajst-32245	109	10	applications	application	NOUN
ajst-32245	109	11	,	,	PUNCT
ajst-32245	109	12	and	and	CCONJ
ajst-32245	109	13	integration	integration	NOUN
ajst-32245	109	14	with	with	ADP
ajst-32245	109	15	artificial	artificial	ADJ
ajst-32245	109	16	intelligence	intelligence	NOUN
ajst-32245	109	17	and	and	CCONJ
ajst-32245	109	18	big	big	ADJ
ajst-32245	109	19	data	datum	NOUN
ajst-32245	109	20	are	be	AUX
ajst-32245	109	21	expected	expect	VERB
ajst-32245	109	22	to	to	PART
ajst-32245	109	23	advance	advance	VERB
ajst-32245	109	24	biosensor	biosensor	NOUN
ajst-32245	109	25	technologies	technology	NOUN
ajst-32245	109	26	.	.	PUNCT
ajst-32245	110	1	by	by	ADP
ajst-32245	110	2	providing	provide	VERB
ajst-32245	110	3	more	more	ADV
ajst-32245	110	4	accurate	accurate	ADJ
ajst-32245	110	5	,	,	PUNCT
ajst-32245	110	6	convenient	convenient	ADJ
ajst-32245	110	7	,	,	PUNCT
ajst-32245	110	8	and	and	CCONJ
ajst-32245	110	9	cost	cost	NOUN
ajst-32245	110	10	-	-	PUNCT
ajst-32245	110	11	effective	effective	ADJ
ajst-32245	110	12	detection	detection	NOUN
ajst-32245	110	13	methods	method	NOUN
ajst-32245	110	14	,	,	PUNCT
ajst-32245	110	15	biosensors	biosensor	NOUN
ajst-32245	110	16	have	have	VERB
ajst-32245	110	17	the	the	DET
ajst-32245	110	18	potential	potential	NOUN
ajst-32245	110	19	to	to	PART
ajst-32245	110	20	fundamentally	fundamentally	ADV
ajst-32245	110	21	transform	transform	VERB
ajst-32245	110	22	early	early	ADJ
ajst-32245	110	23	diagnosis	diagnosis	NOUN
ajst-32245	110	24	and	and	CCONJ
ajst-32245	110	25	management	management	NOUN
ajst-32245	110	26	of	of	ADP
ajst-32245	110	27	ad	ad	NOUN
ajst-32245	110	28	,	,	PUNCT
ajst-32245	110	29	thereby	thereby	ADV
ajst-32245	110	30	alleviating	alleviate	VERB
ajst-32245	110	31	the	the	DET
ajst-32245	110	32	societal	societal	ADJ
ajst-32245	110	33	and	and	CCONJ
ajst-32245	110	34	healthcare	healthcare	NOUN
ajst-32245	110	35	burdens	burden	NOUN
ajst-32245	110	36	associated	associate	VERB
ajst-32245	110	37	with	with	ADP
ajst-32245	110	38	global	global	ADJ
ajst-32245	110	39	aging	aging	NOUN
ajst-32245	110	40	.	.	PUNCT
ajst-32245	111	1	references	reference	NOUN
ajst-32245	111	2	[	[	X
ajst-32245	111	3	1	1	NUM
ajst-32245	111	4	]	]	X
ajst-32245	111	5	lane	lane	NOUN
ajst-32245	111	6	,	,	PUNCT
ajst-32245	111	7	c.a	c.a	PROPN
ajst-32245	111	8	.	.	PROPN
ajst-32245	111	9	,	,	PUNCT
ajst-32245	111	10	j.	j.	PROPN
ajst-32245	111	11	hardy	hardy	PROPN
ajst-32245	111	12	,	,	PUNCT
ajst-32245	111	13	and	and	CCONJ
ajst-32245	111	14	j.m	j.m	PROPN
ajst-32245	111	15	.	.	PROPN
ajst-32245	111	16	schott	schott	PROPN
ajst-32245	111	17	,	,	PUNCT
ajst-32245	111	18	alzheimer	alzheimer	PROPN
ajst-32245	111	19	's	's	PART
ajst-32245	111	20	disease	disease	NOUN
ajst-32245	111	21	.	.	PUNCT
ajst-32245	112	1	european	european	PROPN
ajst-32245	112	2	journal	journal	PROPN
ajst-32245	112	3	of	of	ADP
ajst-32245	112	4	neurology	neurology	NOUN
ajst-32245	112	5	,	,	PUNCT
ajst-32245	112	6	2018	2018	NUM
ajst-32245	112	7	.	.	PUNCT
ajst-32245	113	1	25(1	25(1	NUM
ajst-32245	113	2	):	):	PUNCT
ajst-32245	113	3	p.	p.	NOUN
ajst-32245	113	4	59–70	59–70	NUM
ajst-32245	113	5	.	.	PUNCT
ajst-32245	114	1	[	[	X
ajst-32245	114	2	2	2	NUM
ajst-32245	114	3	]	]	PUNCT
ajst-32245	114	4	scheltens	schelten	NOUN
ajst-32245	114	5	,	,	PUNCT
ajst-32245	114	6	p.	p.	PROPN
ajst-32245	114	7	,	,	PUNCT
ajst-32245	114	8	et	et	PROPN
ajst-32245	114	9	al	al	PROPN
ajst-32245	114	10	.	.	PROPN
ajst-32245	114	11	,	,	PUNCT
ajst-32245	114	12	alzheimer	alzheimer	PROPN
ajst-32245	114	13	's	's	PART
ajst-32245	114	14	disease	disease	NOUN
ajst-32245	114	15	.	.	PUNCT
ajst-32245	115	1	the	the	DET
ajst-32245	115	2	lancet	lancet	NOUN
ajst-32245	115	3	,	,	PUNCT
ajst-32245	115	4	2021	2021	NUM
ajst-32245	115	5	.	.	PUNCT
ajst-32245	116	1	397(10284	397(10284	NUM
ajst-32245	116	2	):	):	PUNCT
ajst-32245	117	1	p.	p.	NOUN
ajst-32245	117	2	1577–1590	1577–1590	NUM
ajst-32245	117	3	.	.	PUNCT
ajst-32245	118	1	[	[	X
ajst-32245	118	2	3	3	NUM
ajst-32245	118	3	]	]	X
ajst-32245	118	4	long	long	ADV
ajst-32245	118	5	,	,	PUNCT
ajst-32245	118	6	j.m	j.m	PROPN
ajst-32245	118	7	.	.	PROPN
ajst-32245	118	8	and	and	CCONJ
ajst-32245	118	9	d.m	d.m	PROPN
ajst-32245	118	10	.	.	PROPN
ajst-32245	118	11	holtzman	holtzman	PROPN
ajst-32245	118	12	,	,	PUNCT
ajst-32245	118	13	alzheimer	alzheimer	PROPN
ajst-32245	118	14	disease	disease	PROPN
ajst-32245	118	15	:	:	PUNCT
ajst-32245	118	16	an	an	DET
ajst-32245	118	17	update	update	NOUN
ajst-32245	118	18	on	on	ADP
ajst-32245	118	19	pathobiology	pathobiology	NOUN
ajst-32245	118	20	and	and	CCONJ
ajst-32245	118	21	treatment	treatment	NOUN
ajst-32245	118	22	strategies	strategy	NOUN
ajst-32245	118	23	.	.	PUNCT
ajst-32245	119	1	cell	cell	NOUN
ajst-32245	119	2	,	,	PUNCT
ajst-32245	119	3	2019	2019	NUM
ajst-32245	119	4	.	.	PUNCT
ajst-32245	120	1	179(2	179(2	NUM
ajst-32245	120	2	):	):	PUNCT
ajst-32245	120	3	p.	p.	PROPN
ajst-32245	120	4	312–339	312–339	NUM
ajst-32245	120	5	.	.	PUNCT
ajst-32245	121	1	[	[	X
ajst-32245	121	2	4	4	NUM
ajst-32245	121	3	]	]	X
ajst-32245	121	4	livingston	livingston	PROPN
ajst-32245	121	5	,	,	PUNCT
ajst-32245	121	6	g.	g.	PROPN
ajst-32245	121	7	,	,	PUNCT
ajst-32245	121	8	et	et	PROPN
ajst-32245	121	9	al	al	PROPN
ajst-32245	121	10	.	.	PROPN
ajst-32245	121	11	,	,	PUNCT
ajst-32245	121	12	dementia	dementia	PROPN
ajst-32245	121	13	prevention	prevention	PROPN
ajst-32245	121	14	,	,	PUNCT
ajst-32245	121	15	intervention	intervention	NOUN
ajst-32245	121	16	,	,	PUNCT
ajst-32245	121	17	and	and	CCONJ
ajst-32245	121	18	care	care	NOUN
ajst-32245	121	19	:	:	PUNCT
ajst-32245	121	20	2020	2020	NUM
ajst-32245	121	21	report	report	NOUN
ajst-32245	121	22	of	of	ADP
ajst-32245	121	23	the	the	DET
ajst-32245	121	24	<	<	X
ajst-32245	121	25	em	em	PROPN
ajst-32245	121	26	>	>	X
ajst-32245	121	27	lancet</em	lancet</em	PROPN
ajst-32245	121	28	>	>	X
ajst-32245	121	29	commission	commission	PROPN
ajst-32245	121	30	.	.	PUNCT
ajst-32245	122	1	the	the	DET
ajst-32245	122	2	lancet	lancet	NOUN
ajst-32245	122	3	,	,	PUNCT
ajst-32245	122	4	2020	2020	NUM
ajst-32245	122	5	.	.	PUNCT
ajst-32245	123	1	396(10248	396(10248	NUM
ajst-32245	123	2	):	):	PUNCT
ajst-32245	123	3	p.	p.	PROPN
ajst-32245	123	4	413–446	413–446	NUM
ajst-32245	123	5	.	.	PUNCT
ajst-32245	124	1	[	[	X
ajst-32245	124	2	5	5	NUM
ajst-32245	124	3	]	]	X
ajst-32245	124	4	park	park	NOUN
ajst-32245	124	5	,	,	PUNCT
ajst-32245	124	6	j.s	j.s	PROPN
ajst-32245	124	7	.	.	PROPN
ajst-32245	124	8	,	,	PUNCT
ajst-32245	124	9	et	et	PROPN
ajst-32245	124	10	al	al	PROPN
ajst-32245	124	11	.	.	PROPN
ajst-32245	124	12	,	,	PUNCT
ajst-32245	124	13	biosensors	biosensor	NOUN
ajst-32245	124	14	and	and	CCONJ
ajst-32245	124	15	biomarkers	biomarker	NOUN
ajst-32245	124	16	:	:	PUNCT
ajst-32245	124	17	a	a	DET
ajst-32245	124	18	dynamic	dynamic	ADJ
ajst-32245	124	19	duo	duo	NOUN
ajst-32245	124	20	towards	towards	ADP
ajst-32245	124	21	alzheimer	alzheimer	PROPN
ajst-32245	124	22	's	's	PART
ajst-32245	124	23	disease	disease	NOUN
ajst-32245	124	24	detection	detection	NOUN
ajst-32245	124	25	.	.	PUNCT
ajst-32245	125	1	sensing	sense	VERB
ajst-32245	125	2	and	and	CCONJ
ajst-32245	125	3	bio	bio	ADV
ajst-32245	125	4	-	-	ADJ
ajst-32245	125	5	sensing	sense	VERB
ajst-32245	125	6	research	research	NOUN
ajst-32245	125	7	,	,	PUNCT
ajst-32245	125	8	2024	2024	NUM
ajst-32245	125	9	.	.	PUNCT
ajst-32245	126	1	46	46	NUM
ajst-32245	126	2	.	.	PUNCT
ajst-32245	127	1	[	[	X
ajst-32245	127	2	6	6	NUM
ajst-32245	127	3	]	]	X
ajst-32245	127	4	naresh	naresh	X
ajst-32245	127	5	,	,	PUNCT
ajst-32245	127	6	v.	v.	PROPN
ajst-32245	127	7	and	and	CCONJ
ajst-32245	127	8	n.	n.	PROPN
ajst-32245	127	9	lee	lee	PROPN
ajst-32245	127	10	,	,	PUNCT
ajst-32245	127	11	a	a	DET
ajst-32245	127	12	review	review	NOUN
ajst-32245	127	13	on	on	ADP
ajst-32245	127	14	biosensors	biosensor	NOUN
ajst-32245	127	15	and	and	CCONJ
ajst-32245	127	16	recent	recent	ADJ
ajst-32245	127	17	development	development	NOUN
ajst-32245	127	18	of	of	ADP
ajst-32245	127	19	nanostructured	nanostructure	VERB
ajst-32245	127	20	materialsenabled	materialsenable	VERB
ajst-32245	127	21	biosensors	biosensor	NOUN
ajst-32245	127	22	.	.	PUNCT
ajst-32245	128	1	sensors	sensor	NOUN
ajst-32245	128	2	,	,	PUNCT
ajst-32245	128	3	2021	2021	NUM
ajst-32245	128	4	.	.	PUNCT
ajst-32245	129	1	21(4	21(4	NUM
ajst-32245	129	2	)	)	PUNCT
ajst-32245	129	3	.	.	PUNCT
ajst-32245	130	1	[	[	X
ajst-32245	130	2	7	7	NUM
ajst-32245	130	3	]	]	X
ajst-32245	130	4	zhang	zhang	PROPN
ajst-32245	130	5	,	,	PUNCT
ajst-32245	130	6	l.	l.	PROPN
ajst-32245	130	7	,	,	PUNCT
ajst-32245	130	8	et	et	PROPN
ajst-32245	130	9	al	al	PROPN
ajst-32245	130	10	.	.	PROPN
ajst-32245	130	11	,	,	PUNCT
ajst-32245	130	12	electrochemical	electrochemical	ADJ
ajst-32245	130	13	biosensors	biosensor	NOUN
ajst-32245	130	14	represent	represent	VERB
ajst-32245	130	15	promising	promise	VERB
ajst-32245	130	16	detection	detection	NOUN
ajst-32245	130	17	tools	tool	NOUN
ajst-32245	130	18	in	in	ADP
ajst-32245	130	19	medical	medical	ADJ
ajst-32245	130	20	field	field	NOUN
ajst-32245	130	21	.	.	PUNCT
ajst-32245	131	1	advanced	advanced	ADJ
ajst-32245	131	2	sensor	sensor	NOUN
ajst-32245	131	3	and	and	CCONJ
ajst-32245	131	4	energy	energy	NOUN
ajst-32245	131	5	materials	material	NOUN
ajst-32245	131	6	,	,	PUNCT
ajst-32245	131	7	2023	2023	NUM
ajst-32245	131	8	.	.	PUNCT
ajst-32245	132	1	2(4	2(4	NUM
ajst-32245	132	2	):	):	PUNCT
ajst-32245	133	1	p.	p.	NOUN
ajst-32245	133	2	100081	100081	NUM
ajst-32245	133	3	.	.	PUNCT
ajst-32245	134	1	[	[	X
ajst-32245	134	2	8	8	NUM
ajst-32245	134	3	]	]	X
ajst-32245	134	4	pan	pan	PROPN
ajst-32245	134	5	,	,	PUNCT
ajst-32245	134	6	m.	m.	NOUN
ajst-32245	134	7	,	,	PUNCT
ajst-32245	134	8	et	et	PROPN
ajst-32245	134	9	al	al	PROPN
ajst-32245	134	10	.	.	PROPN
ajst-32245	134	11	,	,	PUNCT
ajst-32245	134	12	electrochemical	electrochemical	ADJ
ajst-32245	134	13	biosensors	biosensor	NOUN
ajst-32245	134	14	for	for	ADP
ajst-32245	134	15	pathogenic	pathogenic	ADJ
ajst-32245	134	16	microorganisms	microorganism	NOUN
ajst-32245	134	17	detection	detection	NOUN
ajst-32245	134	18	based	base	VERB
ajst-32245	134	19	on	on	ADP
ajst-32245	134	20	recognition	recognition	NOUN
ajst-32245	134	21	elements	element	NOUN
ajst-32245	134	22	.	.	PUNCT
ajst-32245	135	1	folia	folia	PROPN
ajst-32245	135	2	microbiologica	microbiologica	PROPN
ajst-32245	135	3	,	,	PUNCT
ajst-32245	135	4	2024	2024	NUM
ajst-32245	135	5	.	.	PUNCT
ajst-32245	136	1	69(2	69(2	NOUN
ajst-32245	136	2	):	):	PUNCT
ajst-32245	136	3	p.	p.	NOUN
ajst-32245	136	4	283–304	283–304	NUM
ajst-32245	136	5	.	.	PUNCT
ajst-32245	137	1	[	[	X
ajst-32245	137	2	9	9	NUM
ajst-32245	137	3	]	]	SYM
ajst-32245	137	4	altay	altay	NOUN
ajst-32245	137	5	,	,	PUNCT
ajst-32245	137	6	d.n	d.n	PROPN
ajst-32245	137	7	.	.	PROPN
ajst-32245	137	8	,	,	PUNCT
ajst-32245	137	9	h.	h.	PROPN
ajst-32245	137	10	yagar	yagar	PROPN
ajst-32245	137	11	,	,	PUNCT
ajst-32245	137	12	and	and	CCONJ
ajst-32245	137	13	h.m	h.m	PROPN
ajst-32245	137	14	.	.	PROPN
ajst-32245	137	15	ozcan	ozcan	PROPN
ajst-32245	137	16	,	,	PUNCT
ajst-32245	137	17	a	a	DET
ajst-32245	137	18	new	new	ADJ
ajst-32245	137	19	ito	ito	NOUN
ajst-32245	137	20	-	-	PUNCT
ajst-32245	137	21	based	base	VERB
ajst-32245	137	22	aβ42	aβ42	PROPN
ajst-32245	137	23	biosensor	biosensor	NOUN
ajst-32245	137	24	for	for	ADP
ajst-32245	137	25	early	early	ADJ
ajst-32245	137	26	detection	detection	NOUN
ajst-32245	137	27	of	of	ADP
ajst-32245	137	28	alzheimer	alzheimer	PROPN
ajst-32245	137	29	's	's	PART
ajst-32245	137	30	disease	disease	NOUN
ajst-32245	137	31	.	.	PUNCT
ajst-32245	138	1	bioelectrochemistry	bioelectrochemistry	NOUN
ajst-32245	138	2	,	,	PUNCT
ajst-32245	138	3	2023	2023	NUM
ajst-32245	138	4	.	.	PUNCT
ajst-32245	139	1	153	153	NUM
ajst-32245	139	2	:	:	PUNCT
ajst-32245	139	3	p.	p.	NOUN
ajst-32245	139	4	108501	108501	NUM
ajst-32245	139	5	.	.	PUNCT
ajst-32245	140	1	[	[	X
ajst-32245	140	2	10	10	NUM
ajst-32245	140	3	]	]	X
ajst-32245	140	4	ding	ding	NOUN
ajst-32245	140	5	,	,	PUNCT
ajst-32245	140	6	m.	m.	NOUN
ajst-32245	140	7	,	,	PUNCT
ajst-32245	140	8	et	et	PROPN
ajst-32245	140	9	al	al	PROPN
ajst-32245	140	10	.	.	PROPN
ajst-32245	140	11	,	,	PUNCT
ajst-32245	140	12	recent	recent	ADJ
ajst-32245	140	13	advances	advance	NOUN
ajst-32245	140	14	in	in	ADP
ajst-32245	140	15	electrochemical	electrochemical	ADJ
ajst-32245	140	16	biosensors	biosensor	NOUN
ajst-32245	140	17	for	for	ADP
ajst-32245	140	18	the	the	DET
ajst-32245	140	19	detection	detection	NOUN
ajst-32245	140	20	of	of	ADP
ajst-32245	140	21	aβ42	aβ42	PROPN
ajst-32245	140	22	,	,	PUNCT
ajst-32245	140	23	a	a	DET
ajst-32245	140	24	biomarker	biomarker	NOUN
ajst-32245	140	25	for	for	ADP
ajst-32245	140	26	alzheimer	alzheimer	NOUN
ajst-32245	140	27	disease	disease	NOUN
ajst-32245	140	28	diagnosis	diagnosis	NOUN
ajst-32245	140	29	.	.	PUNCT
ajst-32245	141	1	trac	trac	NOUN
ajst-32245	141	2	trends	trend	NOUN
ajst-32245	141	3	in	in	ADP
ajst-32245	141	4	analytical	analytical	ADJ
ajst-32245	141	5	chemistry	chemistry	NOUN
ajst-32245	141	6	,	,	PUNCT
ajst-32245	141	7	2023	2023	NUM
ajst-32245	141	8	.	.	PUNCT
ajst-32245	142	1	164	164	NUM
ajst-32245	142	2	:	:	PUNCT
ajst-32245	143	1	p.	p.	NOUN
ajst-32245	143	2	117087	117087	NUM
ajst-32245	143	3	.	.	PUNCT
ajst-32245	144	1	[	[	X
ajst-32245	144	2	11	11	NUM
ajst-32245	144	3	]	]	X
ajst-32245	144	4	tong	tong	PROPN
ajst-32245	144	5	,	,	PUNCT
ajst-32245	144	6	j.	j.	PROPN
ajst-32245	144	7	,	,	PUNCT
ajst-32245	144	8	et	et	PROPN
ajst-32245	144	9	al	al	PROPN
ajst-32245	144	10	.	.	PROPN
ajst-32245	144	11	,	,	PUNCT
ajst-32245	144	12	poly	poly	ADJ
ajst-32245	144	13	-	-	PUNCT
ajst-32245	144	14	adenine	adenine	NOUN
ajst-32245	144	15	assisted	assist	VERB
ajst-32245	144	16	signaling	signal	VERB
ajst-32245	144	17	displaced	displace	VERB
ajst-32245	144	18	probe	probe	NOUN
ajst-32245	144	19	ratiometric	ratiometric	ADJ
ajst-32245	144	20	electrochemical	electrochemical	ADJ
ajst-32245	144	21	aptasensor	aptasensor	NOUN
ajst-32245	144	22	for	for	ADP
ajst-32245	144	23	accurate	accurate	ADJ
ajst-32245	144	24	detection	detection	NOUN
ajst-32245	144	25	of	of	ADP
ajst-32245	144	26	alzheimer	alzheimer	PROPN
ajst-32245	144	27	’s	’s	PART
ajst-32245	144	28	disease	disease	NOUN
ajst-32245	144	29	aβ	aβ	ADP
ajst-32245	144	30	biomarkers	biomarker	NOUN
ajst-32245	144	31	.	.	PUNCT
ajst-32245	145	1	acs	acs	PROPN
ajst-32245	145	2	applied	apply	VERB
ajst-32245	145	3	materials	material	NOUN
ajst-32245	145	4	&	&	CCONJ
ajst-32245	145	5	amp	amp	PROPN
ajst-32245	145	6	;	;	PUNCT
ajst-32245	145	7	interfaces	interface	NOUN
ajst-32245	145	8	,	,	PUNCT
ajst-32245	145	9	2024	2024	NUM
ajst-32245	145	10	.	.	PUNCT
ajst-32245	146	1	16(46	16(46	NOUN
ajst-32245	146	2	):	):	PUNCT
ajst-32245	146	3	p.	p.	NOUN
ajst-32245	146	4	64297–64306	64297–64306	NUM
ajst-32245	146	5	.	.	PUNCT
ajst-32245	147	1	[	[	X
ajst-32245	147	2	12	12	NUM
ajst-32245	147	3	]	]	X
ajst-32245	147	4	rahman	rahman	PROPN
ajst-32245	147	5	,	,	PUNCT
ajst-32245	147	6	m.m	m.m	PROPN
ajst-32245	147	7	.	.	PROPN
ajst-32245	147	8	,	,	PUNCT
ajst-32245	147	9	et	et	PROPN
ajst-32245	147	10	al	al	PROPN
ajst-32245	147	11	.	.	PROPN
ajst-32245	147	12	,	,	PUNCT
ajst-32245	147	13	development	development	NOUN
ajst-32245	147	14	of	of	ADP
ajst-32245	147	15	a	a	DET
ajst-32245	147	16	highly	highly	ADV
ajst-32245	147	17	sensitive	sensitive	ADJ
ajst-32245	147	18	cnt	cnt	ADJ
ajst-32245	147	19	-	-	ADJ
ajst-32245	147	20	metal	metal	ADJ
ajst-32245	147	21	graphene	graphene	NOUN
ajst-32245	147	22	hybrid	hybrid	ADJ
ajst-32245	147	23	nano	nano	NOUN
ajst-32245	147	24	-	-	PUNCT
ajst-32245	147	25	ida	ida	PROPN
ajst-32245	147	26	electrochemical	electrochemical	ADJ
ajst-32245	147	27	biosensor	biosensor	NOUN
ajst-32245	147	28	for	for	ADP
ajst-32245	147	29	the	the	DET
ajst-32245	147	30	diagnosis	diagnosis	NOUN
ajst-32245	147	31	of	of	ADP
ajst-32245	147	32	alzheimer	alzheimer	PROPN
ajst-32245	147	33	's	's	PART
ajst-32245	147	34	disease	disease	NOUN
ajst-32245	147	35	.	.	PUNCT
ajst-32245	148	1	biomaterials	biomaterial	NOUN
ajst-32245	148	2	science	science	NOUN
ajst-32245	148	3	,	,	PUNCT
ajst-32245	148	4	2024	2024	NUM
ajst-32245	148	5	.	.	PUNCT
ajst-32245	149	1	12(20	12(20	NUM
ajst-32245	149	2	):	):	PUNCT
ajst-32245	149	3	p.	p.	NOUN
ajst-32245	149	4	5203–5214	5203–5214	NUM
ajst-32245	149	5	.	.	PUNCT
ajst-32245	150	1	[	[	X
ajst-32245	150	2	13	13	NUM
ajst-32245	150	3	]	]	X
ajst-32245	150	4	a	a	DET
ajst-32245	150	5	β	β	X
ajst-32245	150	6	-	-	NOUN
ajst-32245	150	7	amyloid(1	amyloid(1	VERB
ajst-32245	150	8	-	-	PUNCT
ajst-32245	150	9	42	42	NUM
ajst-32245	150	10	)	)	PUNCT
ajst-32245	150	11	biosensor	biosensor	NOUN
ajst-32245	150	12	based	base	VERB
ajst-32245	150	13	on	on	ADP
ajst-32245	150	14	molecularly	molecularly	ADV
ajst-32245	150	15	imprinted	imprint	VERB
ajst-32245	150	16	poly	poly	ADJ
ajst-32245	150	17	-	-	PUNCT
ajst-32245	150	18	pyrrole	pyrrole	NOUN
ajst-32245	150	19	for	for	ADP
ajst-32245	150	20	early	early	ADJ
ajst-32245	150	21	diagnosis	diagnosis	NOUN
ajst-32245	150	22	of	of	ADP
ajst-32245	150	23	alzheimer	alzheimer	PROPN
ajst-32245	150	24	’s	’s	PART
ajst-32245	150	25	disease	disease	NOUN
ajst-32245	150	26	.	.	PUNCT
ajst-32245	151	1	journal	journal	PROPN
ajst-32245	151	2	of	of	ADP
ajst-32245	151	3	biomedical	biomedical	ADJ
ajst-32245	151	4	physics	physics	NOUN
ajst-32245	151	5	and	and	CCONJ
ajst-32245	151	6	engineering	engineering	NOUN
ajst-32245	151	7	,	,	PUNCT
ajst-32245	151	8	2021	2021	NUM
ajst-32245	151	9	.	.	PUNCT
ajst-32245	152	1	11(2	11(2	X
ajst-32245	152	2	)	)	PUNCT
ajst-32245	152	3	.	.	PUNCT
ajst-32245	153	1	[	[	X
ajst-32245	153	2	14	14	NUM
ajst-32245	153	3	]	]	X
ajst-32245	153	4	huang	huang	PROPN
ajst-32245	153	5	,	,	PUNCT
ajst-32245	153	6	z.	z.	PROPN
ajst-32245	153	7	,	,	PUNCT
ajst-32245	153	8	et	et	PROPN
ajst-32245	153	9	al	al	PROPN
ajst-32245	153	10	.	.	PROPN
ajst-32245	153	11	,	,	PUNCT
ajst-32245	153	12	electrochemical	electrochemical	ADJ
ajst-32245	153	13	immunosensor	immunosensor	NOUN
ajst-32245	153	14	based	base	VERB
ajst-32245	153	15	on	on	ADP
ajst-32245	153	16	superwettable	superwettable	ADJ
ajst-32245	153	17	microdroplet	microdroplet	NOUN
ajst-32245	153	18	array	array	NOUN
ajst-32245	153	19	for	for	ADP
ajst-32245	153	20	detecting	detect	VERB
ajst-32245	153	21	multiple	multiple	ADJ
ajst-32245	153	22	alzheimer	alzheimer	PROPN
ajst-32245	153	23	’s	’s	PART
ajst-32245	153	24	disease	disease	NOUN
ajst-32245	153	25	biomarkers	biomarker	NOUN
ajst-32245	153	26	.	.	PUNCT
ajst-32245	154	1	frontiers	frontier	NOUN
ajst-32245	154	2	in	in	ADP
ajst-32245	154	3	bioengineering	bioengineering	NOUN
ajst-32245	154	4	and	and	CCONJ
ajst-32245	154	5	biotechnology	biotechnology	NOUN
ajst-32245	154	6	,	,	PUNCT
ajst-32245	154	7	2022	2022	NUM
ajst-32245	154	8	.	.	PUNCT
ajst-32245	155	1	10	10	NUM
ajst-32245	155	2	.	.	X
ajst-32245	155	3	30	30	NUM
ajst-32245	156	1	[	[	SYM
ajst-32245	156	2	15	15	NUM
ajst-32245	156	3	]	]	X
ajst-32245	156	4	tieu	tieu	PROPN
ajst-32245	156	5	,	,	PUNCT
ajst-32245	156	6	m.-v	m.-v	PROPN
ajst-32245	156	7	.	.	PUNCT
ajst-32245	156	8	,	,	PUNCT
ajst-32245	156	9	et	et	PROPN
ajst-32245	156	10	al	al	PROPN
ajst-32245	156	11	.	.	PROPN
ajst-32245	156	12	,	,	PUNCT
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ajst-32245	156	14	impedance	impedance	NOUN
ajst-32245	156	15	-	-	PUNCT
ajst-32245	156	16	based	base	VERB
ajst-32245	156	17	biosensor	biosensor	NOUN
ajst-32245	156	18	for	for	ADP
ajst-32245	156	19	label	label	NOUN
ajst-32245	156	20	-	-	PUNCT
ajst-32245	156	21	free	free	ADJ
ajst-32245	156	22	determination	determination	NOUN
ajst-32245	156	23	of	of	ADP
ajst-32245	156	24	plasma	plasma	NOUN
ajst-32245	156	25	ptau181	ptau181	PROPN
ajst-32245	156	26	levels	level	NOUN
ajst-32245	156	27	for	for	ADP
ajst-32245	156	28	clinically	clinically	ADV
ajst-32245	156	29	accurate	accurate	ADJ
ajst-32245	156	30	diagnosis	diagnosis	NOUN
ajst-32245	156	31	of	of	ADP
ajst-32245	156	32	mild	mild	ADJ
ajst-32245	156	33	cognitive	cognitive	ADJ
ajst-32245	156	34	impairment	impairment	NOUN
ajst-32245	156	35	and	and	CCONJ
ajst-32245	156	36	alzheimer	alzheimer	NOUN
ajst-32245	156	37	's	's	PART
ajst-32245	156	38	disease	disease	NOUN
ajst-32245	156	39	.	.	PUNCT
ajst-32245	157	1	analytica	analytica	PROPN
ajst-32245	157	2	chimica	chimica	PROPN
ajst-32245	157	3	acta	acta	PROPN
ajst-32245	157	4	,	,	PUNCT
ajst-32245	157	5	2023	2023	NUM
ajst-32245	157	6	.	.	PUNCT
ajst-32245	158	1	1273	1273	NUM
ajst-32245	158	2	:	:	PUNCT
ajst-32245	159	1	p.	p.	NOUN
ajst-32245	159	2	341535	341535	NUM
ajst-32245	159	3	.	.	PUNCT
ajst-32245	160	1	[	[	X
ajst-32245	160	2	16	16	NUM
ajst-32245	160	3	]	]	X
ajst-32245	160	4	kong	kong	PROPN
ajst-32245	160	5	,	,	PUNCT
ajst-32245	160	6	q.	q.	PROPN
ajst-32245	160	7	,	,	PUNCT
ajst-32245	160	8	et	et	PROPN
ajst-32245	160	9	al	al	PROPN
ajst-32245	160	10	.	.	PROPN
ajst-32245	160	11	,	,	PUNCT
ajst-32245	160	12	nucleic	nucleic	ADJ
ajst-32245	160	13	acid	acid	NOUN
ajst-32245	160	14	aptamer	aptamer	NOUN
ajst-32245	160	15	-	-	PUNCT
ajst-32245	160	16	based	base	VERB
ajst-32245	160	17	electrochemical	electrochemical	ADJ
ajst-32245	160	18	sensor	sensor	NOUN
ajst-32245	160	19	for	for	ADP
ajst-32245	160	20	the	the	DET
ajst-32245	160	21	detection	detection	NOUN
ajst-32245	160	22	of	of	ADP
ajst-32245	160	23	serum	serum	NOUN
ajst-32245	160	24	p	p	PROPN
ajst-32245	160	25	-	-	PUNCT
ajst-32245	160	26	tau231	tau231	PROPN
ajst-32245	160	27	and	and	CCONJ
ajst-32245	160	28	the	the	DET
ajst-32245	160	29	instant	instant	NOUN
ajst-32245	160	30	screening	screening	NOUN
ajst-32245	160	31	test	test	NOUN
ajst-32245	160	32	of	of	ADP
ajst-32245	160	33	alzheimer	alzheimer	PROPN
ajst-32245	160	34	’s	’s	PART
ajst-32245	160	35	disease	disease	NOUN
ajst-32245	160	36	.	.	PUNCT
ajst-32245	161	1	microchimica	microchimica	PROPN
ajst-32245	161	2	acta	acta	PROPN
ajst-32245	161	3	,	,	PUNCT
ajst-32245	161	4	2024	2024	NUM
ajst-32245	161	5	.	.	PUNCT
ajst-32245	162	1	191(6	191(6	NUM
ajst-32245	162	2	)	)	PUNCT
ajst-32245	162	3	.	.	PUNCT
ajst-32245	163	1	[	[	X
ajst-32245	163	2	17	17	NUM
ajst-32245	163	3	]	]	SYM
ajst-32245	163	4	tang	tang	PROPN
ajst-32245	163	5	,	,	PUNCT
ajst-32245	163	6	r.	r.	PROPN
ajst-32245	163	7	,	,	PUNCT
ajst-32245	163	8	et	et	PROPN
ajst-32245	163	9	al	al	PROPN
ajst-32245	163	10	.	.	PROPN
ajst-32245	163	11	,	,	PUNCT
ajst-32245	163	12	boosting	boost	VERB
ajst-32245	163	13	the	the	DET
ajst-32245	163	14	sensitivity	sensitivity	NOUN
ajst-32245	163	15	for	for	ADP
ajst-32245	163	16	tau	tau	PROPN
ajst-32245	163	17	protein	protein	NOUN
ajst-32245	163	18	detection	detection	NOUN
ajst-32245	163	19	with	with	ADP
ajst-32245	163	20	a	a	DET
ajst-32245	163	21	bifunctional	bifunctional	ADJ
ajst-32245	163	22	nanoenzyme	nanoenzyme	NOUN
ajst-32245	163	23	signal	signal	NOUN
ajst-32245	163	24	amplifier	amplifier	NOUN
ajst-32245	163	25	.	.	PUNCT
ajst-32245	164	1	sensors	sensor	NOUN
ajst-32245	164	2	and	and	CCONJ
ajst-32245	164	3	actuators	actuator	NOUN
ajst-32245	164	4	b	b	X
ajst-32245	164	5	:	:	PUNCT
ajst-32245	164	6	chemical	chemical	NOUN
ajst-32245	164	7	,	,	PUNCT
ajst-32245	164	8	2024	2024	NUM
ajst-32245	164	9	.	.	PUNCT
ajst-32245	165	1	410	410	NUM
ajst-32245	165	2	:	:	PUNCT
ajst-32245	165	3	p.	p.	NOUN
ajst-32245	165	4	135714	135714	NUM
ajst-32245	165	5	.	.	PUNCT
ajst-32245	166	1	[	[	X
ajst-32245	166	2	18	18	NUM
ajst-32245	166	3	]	]	X
ajst-32245	166	4	pereira	pereira	PROPN
ajst-32245	166	5	,	,	PUNCT
ajst-32245	166	6	r.l	r.l	PROPN
ajst-32245	166	7	.	.	PROPN
ajst-32245	166	8	,	,	PUNCT
ajst-32245	166	9	et	et	PROPN
ajst-32245	166	10	al	al	PROPN
ajst-32245	166	11	.	.	PROPN
ajst-32245	166	12	,	,	PUNCT
ajst-32245	166	13	electrochemical	electrochemical	ADJ
ajst-32245	166	14	mirna-34a	mirna-34a	NOUN
ajst-32245	166	15	-	-	PUNCT
ajst-32245	166	16	based	base	VERB
ajst-32245	166	17	biosensor	biosensor	NOUN
ajst-32245	166	18	for	for	ADP
ajst-32245	166	19	the	the	DET
ajst-32245	166	20	diagnosis	diagnosis	NOUN
ajst-32245	166	21	of	of	ADP
ajst-32245	166	22	alzheimer	alzheimer	PROPN
ajst-32245	166	23	’s	’s	PART
ajst-32245	166	24	disease	disease	NOUN
ajst-32245	166	25	.	.	PUNCT
ajst-32245	167	1	bioelectrochemistry	bioelectrochemistry	NOUN
ajst-32245	167	2	,	,	PUNCT
ajst-32245	167	3	2023	2023	NUM
ajst-32245	167	4	.	.	PUNCT
ajst-32245	168	1	154	154	NUM
ajst-32245	168	2	:	:	PUNCT
ajst-32245	169	1	p.	p.	NOUN
ajst-32245	169	2	108553	108553	NUM
ajst-32245	169	3	.	.	PUNCT
ajst-32245	170	1	[	[	X
ajst-32245	170	2	19	19	NUM
ajst-32245	170	3	]	]	X
ajst-32245	170	4	song	song	NOUN
ajst-32245	170	5	,	,	PUNCT
ajst-32245	170	6	s.	s.	PROPN
ajst-32245	170	7	,	,	PUNCT
ajst-32245	170	8	et	et	PROPN
ajst-32245	170	9	al	al	PROPN
ajst-32245	170	10	.	.	PROPN
ajst-32245	170	11	,	,	PUNCT
ajst-32245	170	12	precise	precise	ADJ
ajst-32245	170	13	profiling	profiling	NOUN
ajst-32245	170	14	of	of	ADP
ajst-32245	170	15	exosomal	exosomal	ADJ
ajst-32245	170	16	biomarkers	biomarker	NOUN
ajst-32245	170	17	via	via	ADP
ajst-32245	170	18	programmable	programmable	ADJ
ajst-32245	170	19	curved	curved	ADJ
ajst-32245	170	20	plasmonic	plasmonic	NOUN
ajst-32245	170	21	nanoarchitecture	nanoarchitecture	NOUN
ajst-32245	170	22	-	-	PUNCT
ajst-32245	170	23	based	base	VERB
ajst-32245	170	24	biosensor	biosensor	NOUN
ajst-32245	170	25	for	for	ADP
ajst-32245	170	26	clinical	clinical	ADJ
ajst-32245	170	27	diagnosis	diagnosis	NOUN
ajst-32245	170	28	of	of	ADP
ajst-32245	170	29	alzheimer	alzheimer	PROPN
ajst-32245	170	30	's	's	PART
ajst-32245	170	31	disease	disease	NOUN
ajst-32245	170	32	.	.	PUNCT
ajst-32245	171	1	biosensors	biosensor	NOUN
ajst-32245	171	2	and	and	CCONJ
ajst-32245	171	3	bioelectronics	bioelectronic	NOUN
ajst-32245	171	4	,	,	PUNCT
ajst-32245	171	5	2023	2023	NUM
ajst-32245	171	6	.	.	PUNCT
ajst-32245	172	1	230	230	NUM
ajst-32245	172	2	:	:	PUNCT
ajst-32245	172	3	p.	p.	NOUN
ajst-32245	172	4	115269	115269	NUM
ajst-32245	172	5	.	.	PUNCT
ajst-32245	173	1	[	[	X
ajst-32245	173	2	20	20	NUM
ajst-32245	173	3	]	]	SYM
ajst-32245	173	4	li	li	PROPN
ajst-32245	173	5	,	,	PUNCT
ajst-32245	173	6	m.	m.	NOUN
ajst-32245	173	7	,	,	PUNCT
ajst-32245	173	8	et	et	PROPN
ajst-32245	173	9	al	al	PROPN
ajst-32245	173	10	.	.	PROPN
ajst-32245	173	11	,	,	PUNCT
ajst-32245	173	12	vertical	vertical	ADJ
ajst-32245	173	13	graphene	graphene	NOUN
ajst-32245	173	14	-	-	PUNCT
ajst-32245	173	15	based	base	VERB
ajst-32245	173	16	printed	print	VERB
ajst-32245	173	17	electrochemical	electrochemical	ADJ
ajst-32245	173	18	biosensor	biosensor	NOUN
ajst-32245	173	19	for	for	ADP
ajst-32245	173	20	simultaneous	simultaneous	ADJ
ajst-32245	173	21	detection	detection	NOUN
ajst-32245	173	22	of	of	ADP
ajst-32245	173	23	four	four	NUM
ajst-32245	173	24	alzheimer	alzheimer	NOUN
ajst-32245	173	25	’s	’s	PART
ajst-32245	173	26	disease	disease	NOUN
ajst-32245	173	27	blood	blood	NOUN
ajst-32245	173	28	biomarkers	biomarker	NOUN
ajst-32245	173	29	.	.	PUNCT
ajst-32245	174	1	biosensors	biosensor	NOUN
ajst-32245	174	2	,	,	PUNCT
ajst-32245	174	3	2023	2023	NUM
ajst-32245	174	4	.	.	PUNCT
ajst-32245	175	1	13(8	13(8	NUM
ajst-32245	175	2	):	):	PUNCT
ajst-32245	175	3	p.	p.	NOUN
ajst-32245	175	4	758	758	NUM
ajst-32245	175	5	.	.	PUNCT
ajst-32245	176	1	[	[	X
ajst-32245	176	2	21	21	NUM
ajst-32245	176	3	]	]	X
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ajst-32245	176	5	-	-	PUNCT
ajst-32245	176	6	vanani	vanani	PROPN
ajst-32245	176	7	,	,	PUNCT
ajst-32245	176	8	r.	r.	PROPN
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ajst-32245	176	10	m.	m.	PROPN
ajst-32245	176	11	negahdary	negahdary	PROPN
ajst-32245	176	12	,	,	PUNCT
ajst-32245	176	13	recent	recent	ADJ
ajst-32245	176	14	advances	advance	NOUN
ajst-32245	176	15	in	in	ADP
ajst-32245	176	16	electrochemical	electrochemical	ADJ
ajst-32245	176	17	aptasensors	aptasensor	NOUN
ajst-32245	176	18	and	and	CCONJ
ajst-32245	176	19	genosensors	genosensor	NOUN
ajst-32245	176	20	for	for	ADP
ajst-32245	176	21	the	the	DET
ajst-32245	176	22	detection	detection	NOUN
ajst-32245	176	23	of	of	ADP
ajst-32245	176	24	pathogens	pathogen	NOUN
ajst-32245	176	25	.	.	PUNCT
ajst-32245	177	1	environmental	environmental	ADJ
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ajst-32245	177	3	,	,	PUNCT
ajst-32245	177	4	2024	2024	NUM
ajst-32245	177	5	.	.	PUNCT
ajst-32245	178	1	243	243	NUM
ajst-32245	178	2	:	:	PUNCT
ajst-32245	179	1	p.	p.	NOUN
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ajst-32245	179	3	.	.	PUNCT
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ajst-32245	180	2	22	22	NUM
ajst-32245	180	3	]	]	PUNCT
ajst-32245	180	4	valkova	valkova	PROPN
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ajst-32245	180	9	pohanka	pohanka	NOUN
ajst-32245	180	10	,	,	PUNCT
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ajst-32245	180	12	trends	trend	NOUN
ajst-32245	180	13	in	in	ADP
ajst-32245	180	14	electrochemical	electrochemical	ADJ
ajst-32245	180	15	biosensors	biosensor	NOUN
ajst-32245	180	16	for	for	ADP
ajst-32245	180	17	early	early	ADJ
ajst-32245	180	18	diagnosis	diagnosis	NOUN
ajst-32245	180	19	of	of	ADP
ajst-32245	180	20	alzheimer	alzheimer	PROPN
ajst-32245	180	21	’s	’s	PART
ajst-32245	180	22	disease	disease	NOUN
ajst-32245	180	23	.	.	PUNCT
ajst-32245	181	1	international	international	ADJ
ajst-32245	181	2	journal	journal	PROPN
ajst-32245	181	3	of	of	ADP
ajst-32245	181	4	analytical	analytical	ADJ
ajst-32245	181	5	chemistry	chemistry	NOUN
ajst-32245	181	6	,	,	PUNCT
ajst-32245	181	7	2021	2021	NUM
ajst-32245	181	8	.	.	PUNCT
ajst-32245	182	1	2021	2021	NUM
ajst-32245	182	2	:	:	PUNCT
ajst-32245	183	1	p.	p.	NOUN
ajst-32245	183	2	1–13	1–13	PROPN
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ajst-32245	184	1	[	[	X
ajst-32245	184	2	23	23	NUM
ajst-32245	184	3	]	]	X
ajst-32245	184	4	cao	cao	PROPN
ajst-32245	184	5	,	,	PUNCT
ajst-32245	184	6	l.	l.	PROPN
ajst-32245	184	7	,	,	PUNCT
ajst-32245	184	8	et	et	PROPN
ajst-32245	184	9	al	al	PROPN
ajst-32245	184	10	.	.	PROPN
ajst-32245	184	11	,	,	PUNCT
ajst-32245	184	12	terahertz	terahertz	VERB
ajst-32245	184	13	metamaterial	metamaterial	ADJ
ajst-32245	184	14	sensors	sensor	NOUN
ajst-32245	184	15	:	:	PUNCT
ajst-32245	184	16	design	design	NOUN
ajst-32245	184	17	theory	theory	NOUN
ajst-32245	184	18	,	,	PUNCT
ajst-32245	184	19	optimization	optimization	NOUN
ajst-32245	184	20	approach	approach	NOUN
ajst-32245	184	21	,	,	PUNCT
ajst-32245	184	22	and	and	CCONJ
ajst-32245	184	23	advancements	advancement	NOUN
ajst-32245	184	24	in	in	ADP
ajst-32245	184	25	biosensing	biosense	VERB
ajst-32245	184	26	applications	application	NOUN
ajst-32245	184	27	.	.	PUNCT
ajst-32245	185	1	advanced	advanced	ADJ
ajst-32245	185	2	materials	material	NOUN
ajst-32245	185	3	technologies	technology	NOUN
ajst-32245	185	4	,	,	PUNCT
ajst-32245	185	5	2024	2024	NUM
ajst-32245	185	6	.	.	PUNCT
ajst-32245	185	7	10(9	10(9	NUM
ajst-32245	185	8	)	)	PUNCT
ajst-32245	185	9	.	.	PUNCT
ajst-32245	186	1	[	[	X
ajst-32245	186	2	24	24	NUM
ajst-32245	186	3	]	]	X
ajst-32245	186	4	wang	wang	PROPN
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ajst-32245	186	7	,	,	PUNCT
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ajst-32245	186	9	neural	neural	ADJ
ajst-32245	186	10	networks	network	NOUN
ajst-32245	186	11	for	for	ADP
ajst-32245	186	12	the	the	DET
ajst-32245	186	13	early	early	ADJ
ajst-32245	186	14	diagnosis	diagnosis	NOUN
ajst-32245	186	15	of	of	ADP
ajst-32245	186	16	dementia	dementia	NOUN
ajst-32245	186	17	and	and	CCONJ
ajst-32245	186	18	alzheimer	alzheimer	PROPN
ajst-32245	186	19	’s	’s	PART
ajst-32245	186	20	disease	disease	NOUN
ajst-32245	186	21	from	from	ADP
ajst-32245	186	22	mri	mri	NOUN
ajst-32245	186	23	images	image	NOUN
ajst-32245	186	24	.	.	PUNCT
ajst-32245	186	25	evolving	evolve	VERB
ajst-32245	186	26	systems	system	NOUN
ajst-32245	186	27	,	,	PUNCT
ajst-32245	186	28	2024	2024	NUM
ajst-32245	186	29	.	.	PUNCT
ajst-32245	187	1	15(6	15(6	NUM
ajst-32245	187	2	):	):	PUNCT
ajst-32245	188	1	p.	p.	NOUN
ajst-32245	188	2	2231–2248	2231–2248	NUM
ajst-32245	188	3	.	.	PUNCT
ajst-32245	189	1	[	[	X
ajst-32245	189	2	25	25	NUM
ajst-32245	189	3	]	]	X
ajst-32245	189	4	abdullah	abdullah	PROPN
ajst-32245	189	5	,	,	PUNCT
ajst-32245	189	6	s.a	s.a	PROPN
ajst-32245	189	7	.	.	PROPN
ajst-32245	189	8	,	,	PUNCT
ajst-32245	189	9	et	et	PROPN
ajst-32245	189	10	al	al	PROPN
ajst-32245	189	11	.	.	PROPN
ajst-32245	189	12	,	,	PUNCT
ajst-32245	189	13	functional	functional	ADJ
ajst-32245	189	14	nanomaterials	nanomaterial	NOUN
ajst-32245	189	15	for	for	ADP
ajst-32245	189	16	the	the	DET
ajst-32245	189	17	diagnosis	diagnosis	NOUN
ajst-32245	189	18	of	of	ADP
ajst-32245	189	19	alzheimer	alzheimer	PROPN
ajst-32245	189	20	's	's	PART
ajst-32245	189	21	disease	disease	NOUN
ajst-32245	189	22	:	:	PUNCT
ajst-32245	189	23	recent	recent	ADJ
ajst-32245	189	24	progress	progress	NOUN
ajst-32245	189	25	and	and	CCONJ
ajst-32245	189	26	future	future	ADJ
ajst-32245	189	27	perspectives	perspective	NOUN
ajst-32245	189	28	.	.	PUNCT
ajst-32245	190	1	advanced	advanced	ADJ
ajst-32245	190	2	functional	functional	ADJ
ajst-32245	190	3	materials	material	NOUN
ajst-32245	190	4	,	,	PUNCT
ajst-32245	190	5	2023	2023	NUM
ajst-32245	190	6	.	.	PUNCT
ajst-32245	190	7	33(37	33(37	NUM
ajst-32245	190	8	)	)	PUNCT
ajst-32245	190	9	.	.	PUNCT
ajst-32245	191	1	[	[	X
ajst-32245	191	2	26	26	NUM
ajst-32245	191	3	]	]	X
ajst-32245	191	4	xia	xia	PROPN
ajst-32245	191	5	,	,	PUNCT
ajst-32245	191	6	t.	t.	PROPN
ajst-32245	191	7	,	,	PUNCT
ajst-32245	191	8	et	et	PROPN
ajst-32245	191	9	al	al	PROPN
ajst-32245	191	10	.	.	PROPN
ajst-32245	191	11	,	,	PUNCT
ajst-32245	191	12	mxene	mxene	NOUN
ajst-32245	191	13	-	-	PUNCT
ajst-32245	191	14	based	base	VERB
ajst-32245	191	15	enzymatic	enzymatic	ADJ
ajst-32245	191	16	sensor	sensor	NOUN
ajst-32245	191	17	for	for	ADP
ajst-32245	191	18	highly	highly	ADV
ajst-32245	191	19	sensitive	sensitive	ADJ
ajst-32245	191	20	and	and	CCONJ
ajst-32245	191	21	selective	selective	ADJ
ajst-32245	191	22	detection	detection	NOUN
ajst-32245	191	23	of	of	ADP
ajst-32245	191	24	cholesterol	cholesterol	NOUN
ajst-32245	191	25	.	.	PUNCT
ajst-32245	192	1	biosensors	biosensor	NOUN
ajst-32245	192	2	and	and	CCONJ
ajst-32245	192	3	bioelectronics	bioelectronic	NOUN
ajst-32245	192	4	,	,	PUNCT
ajst-32245	192	5	2021	2021	NUM
ajst-32245	192	6	.	.	PUNCT
ajst-32245	193	1	183	183	NUM
ajst-32245	193	2	:	:	PUNCT
ajst-32245	193	3	p.	p.	NOUN
ajst-32245	193	4	113243	113243	NUM
ajst-32245	193	5	.	.	PUNCT
ajst-32245	194	1	[	[	X
ajst-32245	194	2	27	27	NUM
ajst-32245	194	3	]	]	SYM
ajst-32245	194	4	eksin	eksin	NOUN
ajst-32245	194	5	,	,	PUNCT
ajst-32245	194	6	e.	e.	PROPN
ajst-32245	194	7	and	and	CCONJ
ajst-32245	194	8	a.	a.	PROPN
ajst-32245	194	9	erdem	erdem	PROPN
ajst-32245	194	10	,	,	PUNCT
ajst-32245	194	11	recent	recent	ADJ
ajst-32245	194	12	progress	progress	NOUN
ajst-32245	194	13	on	on	ADP
ajst-32245	194	14	optical	optical	ADJ
ajst-32245	194	15	biosensors	biosensor	NOUN
ajst-32245	194	16	developed	develop	VERB
ajst-32245	194	17	for	for	ADP
ajst-32245	194	18	nucleic	nucleic	ADJ
ajst-32245	194	19	acid	acid	NOUN
ajst-32245	194	20	detection	detection	NOUN
ajst-32245	194	21	related	relate	VERB
ajst-32245	194	22	to	to	ADP
ajst-32245	194	23	infectious	infectious	ADJ
ajst-32245	194	24	viral	viral	ADJ
ajst-32245	194	25	diseases	disease	NOUN
ajst-32245	194	26	.	.	PUNCT
ajst-32245	195	1	micromachines	micromachine	NOUN
ajst-32245	195	2	,	,	PUNCT
ajst-32245	195	3	2023	2023	NUM
ajst-32245	195	4	.	.	PUNCT
ajst-32245	196	1	14(2	14(2	NUM
ajst-32245	196	2	):	):	PUNCT
ajst-32245	197	1	p.	p.	NOUN
ajst-32245	197	2	295	295	NUM
ajst-32245	197	3	.	.	PUNCT
ajst-32245	198	1	[	[	X
ajst-32245	198	2	28	28	NUM
ajst-32245	198	3	]	]	X
ajst-32245	198	4	shakya	shakya	PROPN
ajst-32245	198	5	,	,	PUNCT
ajst-32245	198	6	a.k	a.k	PROPN
ajst-32245	198	7	.	.	PROPN
ajst-32245	198	8	,	,	PUNCT
ajst-32245	198	9	et	et	PROPN
ajst-32245	198	10	al	al	PROPN
ajst-32245	198	11	.	.	PROPN
ajst-32245	198	12	,	,	PUNCT
ajst-32245	198	13	optimized	optimize	VERB
ajst-32245	198	14	design	design	NOUN
ajst-32245	198	15	of	of	ADP
ajst-32245	198	16	plasmonic	plasmonic	ADJ
ajst-32245	198	17	biosensor	biosensor	NOUN
ajst-32245	198	18	for	for	ADP
ajst-32245	198	19	cancer	cancer	NOUN
ajst-32245	198	20	detection	detection	NOUN
ajst-32245	198	21	:	:	PUNCT
ajst-32245	198	22	core	core	NOUN
ajst-32245	198	23	configuration	configuration	NOUN
ajst-32245	198	24	and	and	CCONJ
ajst-32245	198	25	nobel	nobel	PROPN
ajst-32245	198	26	material	material	PROPN
ajst-32245	198	27	coating	coating	NOUN
ajst-32245	198	28	innovation	innovation	NOUN
ajst-32245	198	29	.	.	PUNCT
ajst-32245	199	1	plasmonics	plasmonic	NOUN
ajst-32245	199	2	,	,	PUNCT
ajst-32245	199	3	2024	2024	NUM
ajst-32245	199	4	.	.	PUNCT
ajst-32245	200	1	[	[	X
ajst-32245	200	2	29	29	NUM
ajst-32245	200	3	]	]	SYM
ajst-32245	200	4	vagiakis	vagiaki	NOUN
ajst-32245	200	5	,	,	PUNCT
ajst-32245	200	6	i.	i.	PROPN
ajst-32245	200	7	,	,	PUNCT
ajst-32245	200	8	et	et	PROPN
ajst-32245	200	9	al	al	PROPN
ajst-32245	200	10	.	.	PROPN
ajst-32245	200	11	,	,	PUNCT
ajst-32245	200	12	unlocking	unlock	VERB
ajst-32245	200	13	the	the	DET
ajst-32245	200	14	potential	potential	NOUN
ajst-32245	200	15	of	of	ADP
ajst-32245	200	16	vessel	vessel	NOUN
ajst-32245	200	17	density	density	NOUN
ajst-32245	200	18	and	and	CCONJ
ajst-32245	200	19	the	the	DET
ajst-32245	200	20	foveal	foveal	ADJ
ajst-32245	200	21	avascular	avascular	ADJ
ajst-32245	200	22	zone	zone	NOUN
ajst-32245	200	23	in	in	ADP
ajst-32245	200	24	optical	optical	ADJ
ajst-32245	200	25	coherence	coherence	NOUN
ajst-32245	200	26	tomography	tomography	NOUN
ajst-32245	200	27	angiography	angiography	NOUN
ajst-32245	200	28	as	as	ADP
ajst-32245	200	29	biomarkers	biomarker	NOUN
ajst-32245	200	30	in	in	ADP
ajst-32245	200	31	alzheimer	alzheimer	PROPN
ajst-32245	200	32	’s	’s	PART
ajst-32245	200	33	disease	disease	NOUN
ajst-32245	200	34	.	.	PUNCT
ajst-32245	201	1	healthcare	healthcare	PROPN
ajst-32245	201	2	,	,	PUNCT
ajst-32245	201	3	2024	2024	NUM
ajst-32245	201	4	.	.	PUNCT
ajst-32245	202	1	12(16	12(16	NUM
ajst-32245	202	2	):	):	PUNCT
ajst-32245	202	3	p.	p.	NOUN
ajst-32245	202	4	1589	1589	NUM
ajst-32245	202	5	.	.	PUNCT
ajst-32245	203	1	[	[	X
ajst-32245	203	2	30	30	NUM
ajst-32245	203	3	]	]	SYM
ajst-32245	203	4	turkan	turkan	ADJ
ajst-32245	203	5	,	,	PUNCT
ajst-32245	203	6	y.	y.	PROPN
ajst-32245	203	7	and	and	CCONJ
ajst-32245	203	8	f.b	f.b	PROPN
ajst-32245	203	9	.	.	PROPN
ajst-32245	203	10	tek	tek	PROPN
ajst-32245	203	11	,	,	PUNCT
ajst-32245	203	12	a	a	DET
ajst-32245	203	13	survey	survey	NOUN
ajst-32245	203	14	on	on	ADP
ajst-32245	203	15	automated	automate	VERB
ajst-32245	203	16	diagnosis	diagnosis	NOUN
ajst-32245	203	17	of	of	ADP
ajst-32245	203	18	alzheimer	alzheimer	PROPN
ajst-32245	203	19	's	's	PART
ajst-32245	203	20	disease	disease	NOUN
ajst-32245	203	21	using	use	VERB
ajst-32245	203	22	optical	optical	ADJ
ajst-32245	203	23	coherence	coherence	NOUN
ajst-32245	203	24	tomography	tomography	NOUN
ajst-32245	203	25	and	and	CCONJ
ajst-32245	203	26	angiography	angiography	NOUN
ajst-32245	203	27	.	.	PUNCT
ajst-32245	204	1	undefined	undefined	ADJ
ajst-32245	204	2	,	,	PUNCT
ajst-32245	204	3	2022	2022	NUM
ajst-32245	204	4	.	.	PUNCT
ajst-32245	205	1	[	[	X
ajst-32245	205	2	31	31	NUM
ajst-32245	205	3	]	]	X
ajst-32245	205	4	chen	chen	PROPN
ajst-32245	205	5	,	,	PUNCT
ajst-32245	205	6	y.	y.	PROPN
ajst-32245	205	7	,	,	PUNCT
ajst-32245	205	8	et	et	PROPN
ajst-32245	205	9	al	al	PROPN
ajst-32245	205	10	.	.	PROPN
ajst-32245	205	11	,	,	PUNCT
ajst-32245	205	12	breaking	break	VERB
ajst-32245	205	13	the	the	DET
ajst-32245	205	14	sensitivity	sensitivity	NOUN
ajst-32245	205	15	-	-	PUNCT
ajst-32245	205	16	specificity	specificity	NOUN
ajst-32245	205	17	trade	trade	NOUN
ajst-32245	205	18	-	-	PUNCT
ajst-32245	205	19	off	off	NOUN
ajst-32245	205	20	:	:	PUNCT
ajst-32245	205	21	a	a	DET
ajst-32245	205	22	nanoconfined	nanoconfine	VERB
ajst-32245	205	23	dual	dual	ADJ
ajst-32245	205	24	-	-	PUNCT
ajst-32245	205	25	dna	dna	NOUN
ajst-32245	205	26	aptamer	aptamer	NOUN
ajst-32245	205	27	synergy	synergy	NOUN
ajst-32245	205	28	strategy	strategy	NOUN
ajst-32245	205	29	.	.	PUNCT
ajst-32245	206	1	analytical	analytical	ADJ
ajst-32245	206	2	chemistry	chemistry	NOUN
ajst-32245	206	3	,	,	PUNCT
ajst-32245	206	4	2025	2025	NUM
ajst-32245	206	5	.	.	PUNCT
ajst-32245	207	1	97(22	97(22	NOUN
ajst-32245	207	2	):	):	PUNCT
ajst-32245	207	3	p.	p.	NOUN
ajst-32245	207	4	11874–11882	11874–11882	NUM
ajst-32245	207	5	.	.	PUNCT
ajst-32245	208	1	[	[	X
ajst-32245	208	2	32	32	NUM
ajst-32245	208	3	]	]	SYM
ajst-32245	208	4	abbasi	abbasi	PROPN
ajst-32245	208	5	,	,	PUNCT
ajst-32245	208	6	r.	r.	PROPN
ajst-32245	208	7	,	,	PUNCT
ajst-32245	208	8	et	et	PROPN
ajst-32245	208	9	al	al	PROPN
ajst-32245	208	10	.	.	PROPN
ajst-32245	208	11	,	,	PUNCT
ajst-32245	208	12	optical	optical	ADJ
ajst-32245	208	13	image	image	NOUN
ajst-32245	208	14	sensors	sensor	NOUN
ajst-32245	208	15	for	for	ADP
ajst-32245	208	16	smart	smart	ADJ
ajst-32245	208	17	analytical	analytical	ADJ
ajst-32245	208	18	chemiluminescence	chemiluminescence	NOUN
ajst-32245	208	19	biosensors	biosensor	NOUN
ajst-32245	208	20	.	.	PUNCT
ajst-32245	209	1	bioengineering	bioengineering	NOUN
ajst-32245	209	2	,	,	PUNCT
ajst-32245	209	3	2024	2024	NUM
ajst-32245	209	4	.	.	PUNCT
ajst-32245	210	1	11(9	11(9	NUM
ajst-32245	210	2	):	):	PUNCT
ajst-32245	210	3	p.	p.	NOUN
ajst-32245	210	4	912	912	NUM
ajst-32245	210	5	.	.	PUNCT