id	sid	tid	token	lemma	pos
ajst-32251	1	1	43	43	NUM
ajst-32251	1	2	comparison	comparison	NOUN
ajst-32251	1	3	of	of	ADP
ajst-32251	1	4	the	the	DET
ajst-32251	1	5	structure	structure	NOUN
ajst-32251	1	6	,	,	PUNCT
ajst-32251	1	7	working	work	VERB
ajst-32251	1	8	principle	principle	NOUN
ajst-32251	1	9	,	,	PUNCT
ajst-32251	1	10	materials	material	NOUN
ajst-32251	1	11	,	,	PUNCT
ajst-32251	1	12	advantages	advantage	NOUN
ajst-32251	1	13	,	,	PUNCT
ajst-32251	1	14	disadvantages	disadvantage	NOUN
ajst-32251	1	15	,	,	PUNCT
ajst-32251	1	16	and	and	CCONJ
ajst-32251	1	17	performance	performance	NOUN
ajst-32251	1	18	of	of	ADP
ajst-32251	1	19	four	four	NUM
ajst-32251	1	20	generations	generation	NOUN
ajst-32251	1	21	of	of	ADP
ajst-32251	1	22	glucose	glucose	NOUN
ajst-32251	1	23	biosensors	biosensor	NOUN
ajst-32251	1	24	zihan	zihan	PROPN
ajst-32251	1	25	liu	liu	PROPN
ajst-32251	1	26	st.joseph	st.joseph	PROPN
ajst-32251	1	27	’s	’s	PART
ajst-32251	1	28	morrow	morrow	PROPN
ajst-32251	1	29	park	park	PROPN
ajst-32251	1	30	catholic	catholic	PROPN
ajst-32251	1	31	secondary	secondary	PROPN
ajst-32251	1	32	school	school	PROPN
ajst-32251	1	33	,	,	PUNCT
ajst-32251	1	34	toronto	toronto	PROPN
ajst-32251	1	35	,	,	PUNCT
ajst-32251	1	36	canada	canada	PROPN
ajst-32251	1	37	lexieliu080116@gmail.com	lexieliu080116@gmail.com	PROPN
ajst-32251	1	38	abstract	abstract	PROPN
ajst-32251	1	39	.	.	PUNCT
ajst-32251	2	1	this	this	DET
ajst-32251	2	2	paper	paper	NOUN
ajst-32251	2	3	mainly	mainly	ADV
ajst-32251	2	4	introduced	introduce	VERB
ajst-32251	2	5	the	the	DET
ajst-32251	2	6	history	history	NOUN
ajst-32251	2	7	of	of	ADP
ajst-32251	2	8	development	development	NOUN
ajst-32251	2	9	and	and	CCONJ
ajst-32251	2	10	applications	application	NOUN
ajst-32251	2	11	of	of	ADP
ajst-32251	2	12	glucose	glucose	NOUN
ajst-32251	2	13	biosensors	biosensor	NOUN
ajst-32251	2	14	.	.	PUNCT
ajst-32251	3	1	the	the	DET
ajst-32251	3	2	article	article	NOUN
ajst-32251	3	3	first	first	ADV
ajst-32251	3	4	explains	explain	VERB
ajst-32251	3	5	the	the	DET
ajst-32251	3	6	basic	basic	ADJ
ajst-32251	3	7	composition	composition	NOUN
ajst-32251	3	8	and	and	CCONJ
ajst-32251	3	9	principles	principle	NOUN
ajst-32251	3	10	of	of	ADP
ajst-32251	3	11	biosensors	biosensor	NOUN
ajst-32251	3	12	,	,	PUNCT
ajst-32251	3	13	focusing	focus	VERB
ajst-32251	3	14	on	on	ADP
ajst-32251	3	15	the	the	DET
ajst-32251	3	16	role	role	NOUN
ajst-32251	3	17	of	of	ADP
ajst-32251	3	18	glucose	glucose	NOUN
ajst-32251	3	19	oxidase	oxidase	NOUN
ajst-32251	3	20	in	in	ADP
ajst-32251	3	21	blood	blood	NOUN
ajst-32251	3	22	glucose	glucose	NOUN
ajst-32251	3	23	detection	detection	NOUN
ajst-32251	3	24	.	.	PUNCT
ajst-32251	4	1	subsequently	subsequently	ADV
ajst-32251	4	2	the	the	DET
ajst-32251	4	3	paper	paper	NOUN
ajst-32251	4	4	systematically	systematically	ADV
ajst-32251	4	5	sorted	sort	VERB
ajst-32251	4	6	out	out	ADP
ajst-32251	4	7	the	the	DET
ajst-32251	4	8	evolution	evolution	NOUN
ajst-32251	4	9	of	of	ADP
ajst-32251	4	10	four	four	NUM
ajst-32251	4	11	generations	generation	NOUN
ajst-32251	4	12	of	of	ADP
ajst-32251	4	13	glucose	glucose	NOUN
ajst-32251	4	14	biosensors	biosensor	NOUN
ajst-32251	4	15	:	:	PUNCT
ajst-32251	4	16	the	the	DET
ajst-32251	4	17	first	first	ADJ
ajst-32251	4	18	generation	generation	NOUN
ajst-32251	4	19	of	of	ADP
ajst-32251	4	20	sensors	sensor	NOUN
ajst-32251	4	21	relied	rely	VERB
ajst-32251	4	22	on	on	ADP
ajst-32251	4	23	oxygen	oxygen	NOUN
ajst-32251	4	24	and	and	CCONJ
ajst-32251	4	25	were	be	AUX
ajst-32251	4	26	susceptible	susceptible	ADJ
ajst-32251	4	27	to	to	ADP
ajst-32251	4	28	interference	interference	NOUN
ajst-32251	4	29	,	,	PUNCT
ajst-32251	4	30	resulting	result	VERB
ajst-32251	4	31	in	in	ADP
ajst-32251	4	32	insufficient	insufficient	ADJ
ajst-32251	4	33	accuracy	accuracy	NOUN
ajst-32251	4	34	of	of	ADP
ajst-32251	4	35	the	the	DET
ajst-32251	4	36	final	final	ADJ
ajst-32251	4	37	results	result	NOUN
ajst-32251	4	38	;	;	PUNCT
ajst-32251	4	39	the	the	DET
ajst-32251	4	40	second	second	ADJ
ajst-32251	4	41	generation	generation	NOUN
ajst-32251	4	42	added	add	VERB
ajst-32251	4	43	artificial	artificial	ADJ
ajst-32251	4	44	media	medium	NOUN
ajst-32251	4	45	to	to	PART
ajst-32251	4	46	improve	improve	VERB
ajst-32251	4	47	stability	stability	NOUN
ajst-32251	4	48	and	and	CCONJ
ajst-32251	4	49	response	response	NOUN
ajst-32251	4	50	speed	speed	NOUN
ajst-32251	4	51	;	;	PUNCT
ajst-32251	4	52	the	the	DET
ajst-32251	4	53	third	third	ADJ
ajst-32251	4	54	generation	generation	NOUN
ajst-32251	4	55	enhanced	enhance	VERB
ajst-32251	4	56	specificity	specificity	NOUN
ajst-32251	4	57	and	and	CCONJ
ajst-32251	4	58	accuracy	accuracy	NOUN
ajst-32251	4	59	by	by	ADP
ajst-32251	4	60	achieving	achieve	VERB
ajst-32251	4	61	direct	direct	ADJ
ajst-32251	4	62	electron	electron	NOUN
ajst-32251	4	63	transfer	transfer	NOUN
ajst-32251	4	64	between	between	ADP
ajst-32251	4	65	enzymes	enzyme	NOUN
ajst-32251	4	66	and	and	CCONJ
ajst-32251	4	67	electrodes	electrode	NOUN
ajst-32251	4	68	,	,	PUNCT
ajst-32251	4	69	but	but	CCONJ
ajst-32251	4	70	it	it	PRON
ajst-32251	4	71	was	be	AUX
ajst-32251	4	72	very	very	ADV
ajst-32251	4	73	complex	complex	ADJ
ajst-32251	4	74	;	;	PUNCT
ajst-32251	4	75	the	the	DET
ajst-32251	4	76	latest	late	ADJ
ajst-32251	4	77	fourth	fourth	ADJ
ajst-32251	4	78	generation	generation	NOUN
ajst-32251	4	79	adopted	adopt	VERB
ajst-32251	4	80	an	an	DET
ajst-32251	4	81	enzymefree	enzymefree	ADJ
ajst-32251	4	82	design	design	NOUN
ajst-32251	4	83	,	,	PUNCT
ajst-32251	4	84	using	use	VERB
ajst-32251	4	85	metal	metal	NOUN
ajst-32251	4	86	nanoparticles	nanoparticle	NOUN
ajst-32251	4	87	as	as	ADP
ajst-32251	4	88	electrocatalysts	electrocatalyst	NOUN
ajst-32251	4	89	,	,	PUNCT
ajst-32251	4	90	with	with	ADP
ajst-32251	4	91	high	high	ADJ
ajst-32251	4	92	sensitivity	sensitivity	NOUN
ajst-32251	4	93	,	,	PUNCT
ajst-32251	4	94	low	low	ADJ
ajst-32251	4	95	cost	cost	NOUN
ajst-32251	4	96	and	and	CCONJ
ajst-32251	4	97	excellent	excellent	ADJ
ajst-32251	4	98	stability	stability	NOUN
ajst-32251	4	99	,	,	PUNCT
ajst-32251	4	100	overcoming	overcome	VERB
ajst-32251	4	101	limitations	limitation	NOUN
ajst-32251	4	102	such	such	ADJ
ajst-32251	4	103	as	as	ADP
ajst-32251	4	104	enzyme	enzyme	NOUN
ajst-32251	4	105	degradation	degradation	NOUN
ajst-32251	4	106	.	.	PUNCT
ajst-32251	5	1	keywords	keyword	NOUN
ajst-32251	5	2	:	:	PUNCT
ajst-32251	5	3	biosensor	biosensor	NOUN
ajst-32251	5	4	glucose	glucose	NOUN
ajst-32251	5	5	;	;	PUNCT
ajst-32251	5	6	generation	generation	NOUN
ajst-32251	5	7	;	;	PUNCT
ajst-32251	5	8	nanomaterials	nanomaterial	NOUN
ajst-32251	5	9	;	;	PUNCT
ajst-32251	5	10	electron	electron	NOUN
ajst-32251	5	11	transform	transform	NOUN
ajst-32251	5	12	.	.	PUNCT
ajst-32251	6	1	1	1	X
ajst-32251	6	2	.	.	X
ajst-32251	6	3	introduction	introduction	NOUN
ajst-32251	6	4	a	a	DET
ajst-32251	6	5	biosensor	biosensor	NOUN
ajst-32251	6	6	is	be	AUX
ajst-32251	6	7	a	a	DET
ajst-32251	6	8	device	device	NOUN
ajst-32251	6	9	capable	capable	ADJ
ajst-32251	6	10	of	of	ADP
ajst-32251	6	11	converting	convert	VERB
ajst-32251	6	12	biological	biological	ADJ
ajst-32251	6	13	responses	response	NOUN
ajst-32251	6	14	into	into	ADP
ajst-32251	6	15	electrical	electrical	ADJ
ajst-32251	6	16	signals	signal	NOUN
ajst-32251	6	17	.	.	PUNCT
ajst-32251	7	1	it	it	PRON
ajst-32251	7	2	is	be	AUX
ajst-32251	7	3	an	an	DET
ajst-32251	7	4	integrated	integrated	ADJ
ajst-32251	7	5	receptor	receptor	NOUN
ajst-32251	7	6	-	-	PUNCT
ajst-32251	7	7	transducer	transducer	NOUN
ajst-32251	7	8	system	system	NOUN
ajst-32251	7	9	with	with	ADP
ajst-32251	7	10	many	many	ADJ
ajst-32251	7	11	applications	application	NOUN
ajst-32251	7	12	,	,	PUNCT
ajst-32251	7	13	particularly	particularly	ADV
ajst-32251	7	14	in	in	ADP
ajst-32251	7	15	diagnosing	diagnose	VERB
ajst-32251	7	16	and	and	CCONJ
ajst-32251	7	17	treating	treat	VERB
ajst-32251	7	18	medical	medical	ADJ
ajst-32251	7	19	conditions	condition	NOUN
ajst-32251	7	20	[	[	X
ajst-32251	7	21	1	1	NUM
ajst-32251	7	22	]	]	PUNCT
ajst-32251	7	23	.	.	PUNCT
ajst-32251	8	1	a	a	DET
ajst-32251	8	2	typical	typical	ADJ
ajst-32251	8	3	biosensor	biosensor	NOUN
ajst-32251	8	4	consists	consist	VERB
ajst-32251	8	5	of	of	ADP
ajst-32251	8	6	five	five	NUM
ajst-32251	8	7	fundamental	fundamental	ADJ
ajst-32251	8	8	components	component	NOUN
ajst-32251	8	9	:	:	PUNCT
ajst-32251	8	10	the	the	DET
ajst-32251	8	11	analyte	analyte	NOUN
ajst-32251	8	12	—	—	PUNCT
ajst-32251	8	13	the	the	DET
ajst-32251	8	14	substance	substance	NOUN
ajst-32251	8	15	to	to	PART
ajst-32251	8	16	be	be	AUX
ajst-32251	8	17	detected	detect	VERB
ajst-32251	8	18	,	,	PUNCT
ajst-32251	8	19	the	the	DET
ajst-32251	8	20	bioreceptor	bioreceptor	NOUN
ajst-32251	8	21	—	—	PUNCT
ajst-32251	8	22	a	a	DET
ajst-32251	8	23	biological	biological	ADJ
ajst-32251	8	24	recognition	recognition	NOUN
ajst-32251	8	25	element	element	NOUN
ajst-32251	8	26	that	that	PRON
ajst-32251	8	27	interacts	interact	VERB
ajst-32251	8	28	specifically	specifically	ADV
ajst-32251	8	29	with	with	ADP
ajst-32251	8	30	the	the	DET
ajst-32251	8	31	analyte	analyte	NOUN
ajst-32251	8	32	,	,	PUNCT
ajst-32251	8	33	the	the	DET
ajst-32251	8	34	transducer	transducer	NOUN
ajst-32251	8	35	—	—	PUNCT
ajst-32251	8	36	which	which	PRON
ajst-32251	8	37	converts	convert	VERB
ajst-32251	8	38	the	the	DET
ajst-32251	8	39	biorecognition	biorecognition	NOUN
ajst-32251	8	40	event	event	NOUN
ajst-32251	8	41	into	into	ADP
ajst-32251	8	42	a	a	DET
ajst-32251	8	43	measurable	measurable	ADJ
ajst-32251	8	44	signal	signal	NOUN
ajst-32251	8	45	,	,	PUNCT
ajst-32251	8	46	the	the	DET
ajst-32251	8	47	electronics	electronic	NOUN
ajst-32251	8	48	—	—	PUNCT
ajst-32251	8	49	responsible	responsible	ADJ
ajst-32251	8	50	for	for	ADP
ajst-32251	8	51	signal	signal	ADJ
ajst-32251	8	52	amplification	amplification	NOUN
ajst-32251	8	53	and	and	CCONJ
ajst-32251	8	54	processing	processing	NOUN
ajst-32251	8	55	,	,	PUNCT
ajst-32251	8	56	and	and	CCONJ
ajst-32251	8	57	the	the	DET
ajst-32251	8	58	display	display	NOUN
ajst-32251	8	59	—	—	PUNCT
ajst-32251	8	60	which	which	PRON
ajst-32251	8	61	presents	present	VERB
ajst-32251	8	62	the	the	DET
ajst-32251	8	63	final	final	ADJ
ajst-32251	8	64	results	result	NOUN
ajst-32251	8	65	in	in	ADP
ajst-32251	8	66	a	a	DET
ajst-32251	8	67	readable	readable	ADJ
ajst-32251	8	68	format	format	NOUN
ajst-32251	8	69	[	[	X
ajst-32251	8	70	2	2	NUM
ajst-32251	8	71	]	]	PUNCT
ajst-32251	8	72	.	.	PUNCT
ajst-32251	9	1	glucose	glucose	NOUN
ajst-32251	9	2	biosensors	biosensor	NOUN
ajst-32251	9	3	are	be	AUX
ajst-32251	9	4	essential	essential	ADJ
ajst-32251	9	5	for	for	ADP
ajst-32251	9	6	diabetes	diabetes	NOUN
ajst-32251	9	7	care	care	NOUN
ajst-32251	9	8	,	,	PUNCT
ajst-32251	9	9	yet	yet	CCONJ
ajst-32251	9	10	non	non	ADJ
ajst-32251	9	11	-	-	ADJ
ajst-32251	9	12	invasive	invasive	ADJ
ajst-32251	9	13	monitoring	monitoring	NOUN
ajst-32251	9	14	remains	remain	VERB
ajst-32251	9	15	underdeveloped	underdeveloped	ADJ
ajst-32251	9	16	.	.	PUNCT
ajst-32251	10	1	this	this	DET
ajst-32251	10	2	research	research	NOUN
ajst-32251	10	3	gap	gap	NOUN
ajst-32251	10	4	presents	present	VERB
ajst-32251	10	5	opportunities	opportunity	NOUN
ajst-32251	10	6	for	for	ADP
ajst-32251	10	7	progress	progress	NOUN
ajst-32251	10	8	,	,	PUNCT
ajst-32251	10	9	with	with	ADP
ajst-32251	10	10	advances	advance	NOUN
ajst-32251	10	11	in	in	ADP
ajst-32251	10	12	nanomaterials	nanomaterial	NOUN
ajst-32251	10	13	and	and	CCONJ
ajst-32251	10	14	wearable	wearable	ADJ
ajst-32251	10	15	technologies	technology	NOUN
ajst-32251	10	16	offering	offer	VERB
ajst-32251	10	17	a	a	DET
ajst-32251	10	18	foundation	foundation	NOUN
ajst-32251	10	19	for	for	ADP
ajst-32251	10	20	future	future	ADJ
ajst-32251	10	21	innovation	innovation	NOUN
ajst-32251	10	22	,	,	PUNCT
ajst-32251	10	23	as	as	SCONJ
ajst-32251	10	24	shown	show	VERB
ajst-32251	10	25	in	in	ADP
ajst-32251	10	26	figure	figure	NOUN
ajst-32251	10	27	1	1	NUM
ajst-32251	10	28	.	.	PUNCT
ajst-32251	11	1	figure	figure	NOUN
ajst-32251	11	2	1	1	NUM
ajst-32251	11	3	.	.	PUNCT
ajst-32251	12	1	key	key	ADJ
ajst-32251	12	2	components	component	NOUN
ajst-32251	12	3	of	of	ADP
ajst-32251	12	4	a	a	DET
ajst-32251	12	5	biosensor	biosensor	NOUN
ajst-32251	12	6	,	,	PUNCT
ajst-32251	12	7	including	include	VERB
ajst-32251	12	8	the	the	DET
ajst-32251	12	9	analyte	analyte	NOUN
ajst-32251	12	10	,	,	PUNCT
ajst-32251	12	11	bioreceptor	bioreceptor	NOUN
ajst-32251	12	12	,	,	PUNCT
ajst-32251	12	13	electronics	electronic	NOUN
ajst-32251	12	14	,	,	PUNCT
ajst-32251	12	15	and	and	CCONJ
ajst-32251	12	16	display	display	NOUN
ajst-32251	12	17	.	.	PUNCT
ajst-32251	13	1	[	[	X
ajst-32251	13	2	1	1	X
ajst-32251	13	3	]	]	SYM
ajst-32251	13	4	44	44	NUM
ajst-32251	13	5	this	this	DET
ajst-32251	13	6	review	review	NOUN
ajst-32251	13	7	aims	aim	VERB
ajst-32251	13	8	to	to	PART
ajst-32251	13	9	provide	provide	VERB
ajst-32251	13	10	a	a	DET
ajst-32251	13	11	comprehensive	comprehensive	ADJ
ajst-32251	13	12	understanding	understanding	NOUN
ajst-32251	13	13	of	of	ADP
ajst-32251	13	14	the	the	DET
ajst-32251	13	15	development	development	NOUN
ajst-32251	13	16	and	and	CCONJ
ajst-32251	13	17	progression	progression	NOUN
ajst-32251	13	18	of	of	ADP
ajst-32251	13	19	glucose	glucose	NOUN
ajst-32251	13	20	biosensors	biosensor	NOUN
ajst-32251	13	21	,	,	PUNCT
ajst-32251	13	22	highlighting	highlight	VERB
ajst-32251	13	23	how	how	SCONJ
ajst-32251	13	24	each	each	DET
ajst-32251	13	25	generation	generation	NOUN
ajst-32251	13	26	has	have	AUX
ajst-32251	13	27	addressed	address	VERB
ajst-32251	13	28	the	the	DET
ajst-32251	13	29	limitations	limitation	NOUN
ajst-32251	13	30	of	of	ADP
ajst-32251	13	31	its	its	PRON
ajst-32251	13	32	previous	previous	ADJ
ajst-32251	13	33	generation	generation	NOUN
ajst-32251	13	34	.	.	PUNCT
ajst-32251	14	1	given	give	VERB
ajst-32251	14	2	the	the	DET
ajst-32251	14	3	global	global	ADJ
ajst-32251	14	4	prevalence	prevalence	NOUN
ajst-32251	14	5	of	of	ADP
ajst-32251	14	6	diabetes	diabetes	NOUN
ajst-32251	14	7	and	and	CCONJ
ajst-32251	14	8	the	the	DET
ajst-32251	14	9	critical	critical	ADJ
ajst-32251	14	10	role	role	NOUN
ajst-32251	14	11	of	of	ADP
ajst-32251	14	12	accurate	accurate	ADJ
ajst-32251	14	13	blood	blood	NOUN
ajst-32251	14	14	glucose	glucose	NOUN
ajst-32251	14	15	monitoring	monitoring	NOUN
ajst-32251	14	16	in	in	ADP
ajst-32251	14	17	disease	disease	NOUN
ajst-32251	14	18	management	management	NOUN
ajst-32251	14	19	,	,	PUNCT
ajst-32251	14	20	research	research	NOUN
ajst-32251	14	21	in	in	ADP
ajst-32251	14	22	this	this	DET
ajst-32251	14	23	field	field	NOUN
ajst-32251	14	24	is	be	AUX
ajst-32251	14	25	of	of	ADP
ajst-32251	14	26	considerable	considerable	ADJ
ajst-32251	14	27	importance	importance	NOUN
ajst-32251	14	28	.	.	PUNCT
ajst-32251	15	1	advances	advance	NOUN
ajst-32251	15	2	in	in	ADP
ajst-32251	15	3	biosensor	biosensor	NOUN
ajst-32251	15	4	technology	technology	NOUN
ajst-32251	15	5	improve	improve	VERB
ajst-32251	15	6	patient	patient	ADJ
ajst-32251	15	7	outcomes	outcome	NOUN
ajst-32251	15	8	and	and	CCONJ
ajst-32251	15	9	contribute	contribute	VERB
ajst-32251	15	10	to	to	ADP
ajst-32251	15	11	the	the	DET
ajst-32251	15	12	broader	broad	ADJ
ajst-32251	15	13	pursuit	pursuit	NOUN
ajst-32251	15	14	of	of	ADP
ajst-32251	15	15	accessible	accessible	ADJ
ajst-32251	15	16	and	and	CCONJ
ajst-32251	15	17	reliable	reliable	ADJ
ajst-32251	15	18	healthcare	healthcare	NOUN
ajst-32251	15	19	solutions	solution	NOUN
ajst-32251	15	20	.	.	PUNCT
ajst-32251	16	1	therefore	therefore	ADV
ajst-32251	16	2	,	,	PUNCT
ajst-32251	16	3	this	this	DET
ajst-32251	16	4	study	study	NOUN
ajst-32251	16	5	aims	aim	VERB
ajst-32251	16	6	to	to	PART
ajst-32251	16	7	analyze	analyze	VERB
ajst-32251	16	8	the	the	DET
ajst-32251	16	9	evolution	evolution	NOUN
ajst-32251	16	10	of	of	ADP
ajst-32251	16	11	glucose	glucose	NOUN
ajst-32251	16	12	biosensors	biosensor	NOUN
ajst-32251	16	13	,	,	PUNCT
ajst-32251	16	14	evaluate	evaluate	VERB
ajst-32251	16	15	the	the	DET
ajst-32251	16	16	strengths	strength	NOUN
ajst-32251	16	17	and	and	CCONJ
ajst-32251	16	18	limitations	limitation	NOUN
ajst-32251	16	19	of	of	ADP
ajst-32251	16	20	each	each	DET
ajst-32251	16	21	generation	generation	NOUN
ajst-32251	16	22	,	,	PUNCT
ajst-32251	16	23	and	and	CCONJ
ajst-32251	16	24	consider	consider	VERB
ajst-32251	16	25	future	future	ADJ
ajst-32251	16	26	directions	direction	NOUN
ajst-32251	16	27	that	that	PRON
ajst-32251	16	28	may	may	AUX
ajst-32251	16	29	lead	lead	VERB
ajst-32251	16	30	to	to	ADP
ajst-32251	16	31	more	more	ADV
ajst-32251	16	32	effective	effective	ADJ
ajst-32251	16	33	,	,	PUNCT
ajst-32251	16	34	stable	stable	ADJ
ajst-32251	16	35	,	,	PUNCT
ajst-32251	16	36	and	and	CCONJ
ajst-32251	16	37	user	user	NOUN
ajst-32251	16	38	-	-	PUNCT
ajst-32251	16	39	friendly	friendly	ADJ
ajst-32251	16	40	devices	device	NOUN
ajst-32251	16	41	.	.	PUNCT
ajst-32251	17	1	this	this	DET
ajst-32251	17	2	passage	passage	NOUN
ajst-32251	17	3	will	will	AUX
ajst-32251	17	4	focus	focus	VERB
ajst-32251	17	5	exclusively	exclusively	ADV
ajst-32251	17	6	on	on	ADP
ajst-32251	17	7	the	the	DET
ajst-32251	17	8	glucose	glucose	NOUN
ajst-32251	17	9	biosensor	biosensor	NOUN
ajst-32251	17	10	.	.	PUNCT
ajst-32251	18	1	figure	figure	NOUN
ajst-32251	18	2	2	2	NUM
ajst-32251	18	3	.	.	X
ajst-32251	19	1	illustration	illustration	NOUN
ajst-32251	19	2	of	of	ADP
ajst-32251	19	3	the	the	DET
ajst-32251	19	4	three	three	NUM
ajst-32251	19	5	generations	generation	NOUN
ajst-32251	19	6	of	of	ADP
ajst-32251	19	7	biosensors.[1	biosensors.[1	NOUN
ajst-32251	19	8	]	]	X
ajst-32251	19	9	2	2	X
ajst-32251	19	10	.	.	X
ajst-32251	19	11	development	development	NOUN
ajst-32251	19	12	of	of	ADP
ajst-32251	19	13	glucose	glucose	NOUN
ajst-32251	19	14	biosensors	biosensor	NOUN
ajst-32251	19	15	various	various	ADJ
ajst-32251	19	16	glucose	glucose	NOUN
ajst-32251	19	17	biosensors	biosensor	NOUN
ajst-32251	19	18	have	have	AUX
ajst-32251	19	19	been	be	AUX
ajst-32251	19	20	developed	develop	VERB
ajst-32251	19	21	over	over	ADP
ajst-32251	19	22	the	the	DET
ajst-32251	19	23	past	past	ADJ
ajst-32251	19	24	several	several	ADJ
ajst-32251	19	25	years	year	NOUN
ajst-32251	19	26	,	,	PUNCT
ajst-32251	19	27	each	each	PRON
ajst-32251	19	28	with	with	ADP
ajst-32251	19	29	distinct	distinct	ADJ
ajst-32251	19	30	working	working	NOUN
ajst-32251	19	31	principles	principle	NOUN
ajst-32251	19	32	,	,	PUNCT
ajst-32251	19	33	materials	material	NOUN
ajst-32251	19	34	,	,	PUNCT
ajst-32251	19	35	and	and	CCONJ
ajst-32251	19	36	technological	technological	ADJ
ajst-32251	19	37	advancements	advancement	NOUN
ajst-32251	19	38	.	.	PUNCT
ajst-32251	20	1	in	in	ADP
ajst-32251	20	2	the	the	DET
ajst-32251	20	3	following	follow	VERB
ajst-32251	20	4	sections	section	NOUN
ajst-32251	20	5	,	,	PUNCT
ajst-32251	20	6	this	this	DET
ajst-32251	20	7	passage	passage	NOUN
ajst-32251	20	8	will	will	AUX
ajst-32251	20	9	explain	explain	VERB
ajst-32251	20	10	each	each	DET
ajst-32251	20	11	type	type	NOUN
ajst-32251	20	12	in	in	ADP
ajst-32251	20	13	detail	detail	NOUN
ajst-32251	20	14	,	,	PUNCT
ajst-32251	20	15	highlighting	highlight	VERB
ajst-32251	20	16	their	their	PRON
ajst-32251	20	17	structure	structure	NOUN
ajst-32251	20	18	,	,	PUNCT
ajst-32251	20	19	mechanism	mechanism	NOUN
ajst-32251	20	20	of	of	ADP
ajst-32251	20	21	action	action	NOUN
ajst-32251	20	22	,	,	PUNCT
ajst-32251	20	23	and	and	CCONJ
ajst-32251	20	24	practical	practical	ADJ
ajst-32251	20	25	applications	application	NOUN
ajst-32251	20	26	.	.	PUNCT
ajst-32251	21	1	a	a	DET
ajst-32251	21	2	glucose	glucose	NOUN
ajst-32251	21	3	biosensor	biosensor	NOUN
ajst-32251	21	4	is	be	AUX
ajst-32251	21	5	an	an	DET
ajst-32251	21	6	analytical	analytical	ADJ
ajst-32251	21	7	device	device	NOUN
ajst-32251	21	8	that	that	PRON
ajst-32251	21	9	combines	combine	VERB
ajst-32251	21	10	a	a	DET
ajst-32251	21	11	biological	biological	ADJ
ajst-32251	21	12	sensing	sense	VERB
ajst-32251	21	13	element	element	NOUN
ajst-32251	21	14	,	,	PUNCT
ajst-32251	21	15	such	such	ADJ
ajst-32251	21	16	as	as	ADP
ajst-32251	21	17	glucose	glucose	NOUN
ajst-32251	21	18	oxidase	oxidase	NOUN
ajst-32251	21	19	,	,	PUNCT
ajst-32251	21	20	with	with	ADP
ajst-32251	21	21	a	a	DET
ajst-32251	21	22	physicochemical	physicochemical	ADJ
ajst-32251	21	23	transducer	transducer	NOUN
ajst-32251	21	24	to	to	PART
ajst-32251	21	25	detect	detect	VERB
ajst-32251	21	26	and	and	CCONJ
ajst-32251	21	27	measure	measure	VERB
ajst-32251	21	28	glucose	glucose	NOUN
ajst-32251	21	29	concentration	concentration	NOUN
ajst-32251	21	30	.	.	PUNCT
ajst-32251	22	1	this	this	DET
ajst-32251	22	2	type	type	NOUN
ajst-32251	22	3	of	of	ADP
ajst-32251	22	4	biosensor	biosensor	NOUN
ajst-32251	22	5	is	be	AUX
ajst-32251	22	6	widely	widely	ADV
ajst-32251	22	7	used	use	VERB
ajst-32251	22	8	in	in	ADP
ajst-32251	22	9	clinical	clinical	ADJ
ajst-32251	22	10	diagnostics	diagnostic	NOUN
ajst-32251	22	11	,	,	PUNCT
ajst-32251	22	12	especially	especially	ADV
ajst-32251	22	13	for	for	ADP
ajst-32251	22	14	monitoring	monitor	VERB
ajst-32251	22	15	blood	blood	NOUN
ajst-32251	22	16	glucose	glucose	NOUN
ajst-32251	22	17	levels	level	NOUN
ajst-32251	22	18	in	in	ADP
ajst-32251	22	19	patients	patient	NOUN
ajst-32251	22	20	with	with	ADP
ajst-32251	22	21	diabetes	diabetes	NOUN
ajst-32251	22	22	[	[	X
ajst-32251	22	23	3	3	NUM
ajst-32251	22	24	]	]	PUNCT
ajst-32251	22	25	.	.	PUNCT
ajst-32251	23	1	in	in	ADP
ajst-32251	23	2	1976	1976	NUM
ajst-32251	23	3	,	,	PUNCT
ajst-32251	23	4	clemens	clemen	VERB
ajst-32251	23	5	et	et	PROPN
ajst-32251	23	6	al	al	PROPN
ajst-32251	23	7	.	.	PROPN
ajst-32251	23	8	applied	apply	VERB
ajst-32251	23	9	the	the	DET
ajst-32251	23	10	glucose	glucose	NOUN
ajst-32251	23	11	biosensor	biosensor	NOUN
ajst-32251	23	12	to	to	PART
ajst-32251	23	13	develop	develop	VERB
ajst-32251	23	14	a	a	DET
ajst-32251	23	15	“	"	PUNCT
ajst-32251	23	16	bedside	bedside	NOUN
ajst-32251	23	17	artificial	artificial	ADJ
ajst-32251	23	18	pancreas	pancrea	NOUN
ajst-32251	23	19	.	.	PUNCT
ajst-32251	23	20	”	"	PUNCT
ajst-32251	24	1	[	[	X
ajst-32251	24	2	4,5	4,5	NUM
ajst-32251	24	3	]	]	PUNCT
ajst-32251	24	4	additionally	additionally	ADV
ajst-32251	24	5	,	,	PUNCT
ajst-32251	24	6	the	the	DET
ajst-32251	24	7	la	la	PROPN
ajst-32251	24	8	640	640	NUM
ajst-32251	24	9	lactate	lactate	NOUN
ajst-32251	24	10	analyzer	analyzer	NOUN
ajst-32251	24	11	is	be	AUX
ajst-32251	24	12	an	an	DET
ajst-32251	24	13	improved	improved	ADJ
ajst-32251	24	14	device	device	NOUN
ajst-32251	24	15	that	that	PRON
ajst-32251	24	16	enhances	enhance	VERB
ajst-32251	24	17	the	the	DET
ajst-32251	24	18	transfer	transfer	NOUN
ajst-32251	24	19	of	of	ADP
ajst-32251	24	20	electrons	electron	NOUN
ajst-32251	24	21	from	from	ADP
ajst-32251	24	22	lactate	lactate	NOUN
ajst-32251	24	23	dehydrogenase	dehydrogenase	NOUN
ajst-32251	24	24	to	to	ADP
ajst-32251	24	25	the	the	DET
ajst-32251	24	26	electrode	electrode	NOUN
ajst-32251	24	27	,	,	PUNCT
ajst-32251	24	28	enabling	enable	VERB
ajst-32251	24	29	accurate	accurate	ADJ
ajst-32251	24	30	and	and	CCONJ
ajst-32251	24	31	efficient	efficient	ADJ
ajst-32251	24	32	measurement	measurement	NOUN
ajst-32251	24	33	of	of	ADP
ajst-32251	24	34	lactate	lactate	NOUN
ajst-32251	24	35	level	level	NOUN
ajst-32251	24	36	[	[	X
ajst-32251	24	37	6	6	NUM
ajst-32251	24	38	]	]	PUNCT
ajst-32251	24	39	.	.	PUNCT
ajst-32251	25	1	in	in	ADP
ajst-32251	25	2	1987	1987	NUM
ajst-32251	25	3	,	,	PUNCT
ajst-32251	25	4	researchers	researcher	NOUN
ajst-32251	25	5	at	at	ADP
ajst-32251	25	6	cambridge	cambridge	PROPN
ajst-32251	25	7	university	university	PROPN
ajst-32251	25	8	in	in	ADP
ajst-32251	25	9	the	the	DET
ajst-32251	25	10	united	united	PROPN
ajst-32251	25	11	states	states	PROPN
ajst-32251	25	12	developed	develop	VERB
ajst-32251	25	13	a	a	DET
ajst-32251	25	14	pen	pen	NOUN
ajst-32251	25	15	-	-	PUNCT
ajst-32251	25	16	shaped	shape	VERB
ajst-32251	25	17	glucose	glucose	NOUN
ajst-32251	25	18	meter	meter	NOUN
ajst-32251	25	19	to	to	PART
ajst-32251	25	20	measure	measure	VERB
ajst-32251	25	21	blood	blood	NOUN
ajst-32251	25	22	glucose	glucose	NOUN
ajst-32251	25	23	levels	level	NOUN
ajst-32251	25	24	quickly	quickly	ADV
ajst-32251	25	25	and	and	CCONJ
ajst-32251	25	26	conveniently	conveniently	ADV
ajst-32251	25	27	.	.	PUNCT
ajst-32251	26	1	2.1	2.1	NUM
ajst-32251	26	2	the	the	DET
ajst-32251	26	3	first	first	ADJ
ajst-32251	26	4	-	-	PUNCT
ajst-32251	26	5	generation	generation	NOUN
ajst-32251	26	6	biosensor	biosensor	NOUN
ajst-32251	26	7	the	the	DET
ajst-32251	26	8	first	first	ADJ
ajst-32251	26	9	type	type	NOUN
ajst-32251	26	10	of	of	ADP
ajst-32251	26	11	glucose	glucose	NOUN
ajst-32251	26	12	biosensor	biosensor	NOUN
ajst-32251	26	13	operates	operate	VERB
ajst-32251	26	14	by	by	ADP
ajst-32251	26	15	detecting	detect	VERB
ajst-32251	26	16	either	either	CCONJ
ajst-32251	26	17	the	the	DET
ajst-32251	26	18	concentration	concentration	NOUN
ajst-32251	26	19	of	of	ADP
ajst-32251	26	20	the	the	DET
ajst-32251	26	21	analyte	analyte	NOUN
ajst-32251	26	22	—	—	PUNCT
ajst-32251	26	23	glucose	glucose	NOUN
ajst-32251	26	24	in	in	ADP
ajst-32251	26	25	this	this	DET
ajst-32251	26	26	case	case	NOUN
ajst-32251	26	27	—	—	PUNCT
ajst-32251	26	28	or	or	CCONJ
ajst-32251	26	29	the	the	DET
ajst-32251	26	30	molecular	molecular	ADJ
ajst-32251	26	31	products	product	NOUN
ajst-32251	26	32	generated	generate	VERB
ajst-32251	26	33	from	from	ADP
ajst-32251	26	34	its	its	PRON
ajst-32251	26	35	enzymatic	enzymatic	ADJ
ajst-32251	26	36	reaction	reaction	NOUN
ajst-32251	26	37	.	.	PUNCT
ajst-32251	27	1	these	these	DET
ajst-32251	27	2	molecules	molecule	NOUN
ajst-32251	27	3	diffuse	diffuse	VERB
ajst-32251	27	4	to	to	ADP
ajst-32251	27	5	the	the	DET
ajst-32251	27	6	sensor	sensor	NOUN
ajst-32251	27	7	's	's	PART
ajst-32251	27	8	surface	surface	NOUN
ajst-32251	27	9	,	,	PUNCT
ajst-32251	27	10	undergoing	undergo	VERB
ajst-32251	27	11	electrochemical	electrochemical	ADJ
ajst-32251	27	12	reactions	reaction	NOUN
ajst-32251	27	13	that	that	PRON
ajst-32251	27	14	produce	produce	VERB
ajst-32251	27	15	an	an	DET
ajst-32251	27	16	electrical	electrical	ADJ
ajst-32251	27	17	signal	signal	NOUN
ajst-32251	27	18	.	.	PUNCT
ajst-32251	28	1	the	the	DET
ajst-32251	28	2	magnitude	magnitude	NOUN
ajst-32251	28	3	of	of	ADP
ajst-32251	28	4	this	this	DET
ajst-32251	28	5	signal	signal	NOUN
ajst-32251	28	6	is	be	AUX
ajst-32251	28	7	directly	directly	ADV
ajst-32251	28	8	proportional	proportional	ADJ
ajst-32251	28	9	to	to	ADP
ajst-32251	28	10	the	the	DET
ajst-32251	28	11	glucose	glucose	NOUN
ajst-32251	28	12	concentration	concentration	NOUN
ajst-32251	28	13	in	in	ADP
ajst-32251	28	14	the	the	DET
ajst-32251	28	15	sample	sample	NOUN
ajst-32251	28	16	[	[	X
ajst-32251	28	17	7	7	NUM
ajst-32251	28	18	]	]	PUNCT
ajst-32251	28	19	.	.	PUNCT
ajst-32251	29	1	this	this	DET
ajst-32251	29	2	type	type	NOUN
ajst-32251	29	3	of	of	ADP
ajst-32251	29	4	biosensor	biosensor	NOUN
ajst-32251	29	5	is	be	AUX
ajst-32251	29	6	referred	refer	VERB
ajst-32251	29	7	to	to	ADP
ajst-32251	29	8	as	as	ADP
ajst-32251	29	9	a	a	DET
ajst-32251	29	10	mediator	mediator	NOUN
ajst-32251	29	11	-	-	PUNCT
ajst-32251	29	12	less	less	ADJ
ajst-32251	29	13	amperometric	amperometric	NOUN
ajst-32251	29	14	biosensor	biosensor	NOUN
ajst-32251	29	15	45	45	NUM
ajst-32251	29	16	because	because	SCONJ
ajst-32251	29	17	it	it	PRON
ajst-32251	29	18	does	do	AUX
ajst-32251	29	19	not	not	PART
ajst-32251	29	20	utilize	utilize	VERB
ajst-32251	29	21	artificial	artificial	ADJ
ajst-32251	29	22	electron	electron	NOUN
ajst-32251	29	23	mediators	mediator	NOUN
ajst-32251	29	24	;	;	PUNCT
ajst-32251	29	25	instead	instead	ADV
ajst-32251	29	26	,	,	PUNCT
ajst-32251	29	27	it	it	PRON
ajst-32251	29	28	relies	rely	VERB
ajst-32251	29	29	on	on	ADP
ajst-32251	29	30	natural	natural	ADJ
ajst-32251	29	31	electron	electron	NOUN
ajst-32251	29	32	acceptors	acceptor	NOUN
ajst-32251	29	33	such	such	ADJ
ajst-32251	29	34	as	as	ADP
ajst-32251	29	35	oxygen	oxygen	NOUN
ajst-32251	29	36	.	.	PUNCT
ajst-32251	30	1	the	the	DET
ajst-32251	30	2	enzyme	enzyme	NOUN
ajst-32251	30	3	glucose	glucose	NOUN
ajst-32251	30	4	oxidase	oxidase	NOUN
ajst-32251	30	5	catalyzes	catalyze	NOUN
ajst-32251	30	6	glucose	glucose	NOUN
ajst-32251	30	7	oxidation	oxidation	NOUN
ajst-32251	30	8	to	to	ADP
ajst-32251	30	9	gluconic	gluconic	ADJ
ajst-32251	30	10	acid	acid	NOUN
ajst-32251	30	11	in	in	ADP
ajst-32251	30	12	this	this	DET
ajst-32251	30	13	system	system	NOUN
ajst-32251	30	14	.	.	PUNCT
ajst-32251	31	1	during	during	ADP
ajst-32251	31	2	this	this	DET
ajst-32251	31	3	enzymatic	enzymatic	ADJ
ajst-32251	31	4	reaction	reaction	NOUN
ajst-32251	31	5	,	,	PUNCT
ajst-32251	31	6	oxygen	oxygen	NOUN
ajst-32251	31	7	is	be	AUX
ajst-32251	31	8	reduced	reduce	VERB
ajst-32251	31	9	to	to	ADP
ajst-32251	31	10	hydrogen	hydrogen	NOUN
ajst-32251	31	11	peroxide	peroxide	NOUN
ajst-32251	31	12	(	(	PUNCT
ajst-32251	31	13	h₂o₂	h₂o₂	NOUN
ajst-32251	31	14	)	)	PUNCT
ajst-32251	31	15	.	.	PUNCT
ajst-32251	32	1	the	the	DET
ajst-32251	32	2	hydrogen	hydrogen	NOUN
ajst-32251	32	3	peroxide	peroxide	NOUN
ajst-32251	32	4	produced	produce	VERB
ajst-32251	32	5	,	,	PUNCT
ajst-32251	32	6	or	or	CCONJ
ajst-32251	32	7	oxygen	oxygen	NOUN
ajst-32251	32	8	consumption	consumption	NOUN
ajst-32251	32	9	,	,	PUNCT
ajst-32251	32	10	is	be	AUX
ajst-32251	32	11	then	then	ADV
ajst-32251	32	12	electrochemically	electrochemically	ADV
ajst-32251	32	13	detected	detect	VERB
ajst-32251	32	14	at	at	ADP
ajst-32251	32	15	the	the	DET
ajst-32251	32	16	electrode	electrode	NOUN
ajst-32251	32	17	surface	surface	NOUN
ajst-32251	32	18	.	.	PUNCT
ajst-32251	33	1	this	this	PRON
ajst-32251	33	2	generates	generate	VERB
ajst-32251	33	3	an	an	DET
ajst-32251	33	4	electrical	electrical	ADJ
ajst-32251	33	5	current	current	NOUN
ajst-32251	33	6	that	that	PRON
ajst-32251	33	7	is	be	AUX
ajst-32251	33	8	directly	directly	ADV
ajst-32251	33	9	proportional	proportional	ADJ
ajst-32251	33	10	to	to	ADP
ajst-32251	33	11	the	the	DET
ajst-32251	33	12	glucose	glucose	NOUN
ajst-32251	33	13	concentration	concentration	NOUN
ajst-32251	33	14	in	in	ADP
ajst-32251	33	15	the	the	DET
ajst-32251	33	16	sample	sample	NOUN
ajst-32251	33	17	.	.	PUNCT
ajst-32251	34	1	this	this	DET
ajst-32251	34	2	method	method	NOUN
ajst-32251	34	3	was	be	AUX
ajst-32251	34	4	first	first	ADV
ajst-32251	34	5	described	describe	VERB
ajst-32251	34	6	experimentally	experimentally	ADV
ajst-32251	34	7	by	by	ADP
ajst-32251	34	8	leland	leland	PROPN
ajst-32251	34	9	c.	c.	PROPN
ajst-32251	34	10	clark	clark	PROPN
ajst-32251	34	11	jr	jr	PROPN
ajst-32251	34	12	.	.	PROPN
ajst-32251	34	13	in	in	ADP
ajst-32251	34	14	1962	1962	NUM
ajst-32251	34	15	,	,	PUNCT
ajst-32251	34	16	following	follow	VERB
ajst-32251	34	17	his	his	PRON
ajst-32251	34	18	earlier	early	ADJ
ajst-32251	34	19	foundational	foundational	ADJ
ajst-32251	34	20	work	work	NOUN
ajst-32251	34	21	on	on	ADP
ajst-32251	34	22	the	the	DET
ajst-32251	34	23	oxygen	oxygen	NOUN
ajst-32251	34	24	electrode	electrode	NOUN
ajst-32251	34	25	published	publish	VERB
ajst-32251	34	26	in	in	ADP
ajst-32251	34	27	1956[8	1956[8	NUM
ajst-32251	34	28	]	]	PUNCT
ajst-32251	34	29	.	.	PUNCT
ajst-32251	35	1	2.2	2.2	NUM
ajst-32251	35	2	the	the	DET
ajst-32251	35	3	second	second	ADJ
ajst-32251	35	4	-	-	PUNCT
ajst-32251	35	5	generation	generation	NOUN
ajst-32251	35	6	biosensor	biosensor	NOUN
ajst-32251	35	7	the	the	DET
ajst-32251	35	8	working	work	VERB
ajst-32251	35	9	principle	principle	NOUN
ajst-32251	35	10	of	of	ADP
ajst-32251	35	11	the	the	DET
ajst-32251	35	12	second	second	ADJ
ajst-32251	35	13	-	-	PUNCT
ajst-32251	35	14	generation	generation	NOUN
ajst-32251	35	15	glucose	glucose	NOUN
ajst-32251	35	16	biosensor	biosensor	NOUN
ajst-32251	35	17	involves	involve	VERB
ajst-32251	35	18	integrating	integrate	VERB
ajst-32251	35	19	artificial	artificial	ADJ
ajst-32251	35	20	electron	electron	NOUN
ajst-32251	35	21	mediators	mediator	NOUN
ajst-32251	35	22	into	into	ADP
ajst-32251	35	23	the	the	DET
ajst-32251	35	24	sensor	sensor	NOUN
ajst-32251	35	25	's	's	PART
ajst-32251	35	26	biological	biological	ADJ
ajst-32251	35	27	recognition	recognition	NOUN
ajst-32251	35	28	layer	layer	NOUN
ajst-32251	35	29	.	.	PUNCT
ajst-32251	36	1	these	these	DET
ajst-32251	36	2	mediators	mediator	NOUN
ajst-32251	36	3	are	be	AUX
ajst-32251	36	4	typically	typically	ADV
ajst-32251	36	5	small	small	ADJ
ajst-32251	36	6	molecules	molecule	NOUN
ajst-32251	36	7	with	with	ADP
ajst-32251	36	8	redox	redox	ADJ
ajst-32251	36	9	activity	activity	NOUN
ajst-32251	36	10	,	,	PUNCT
ajst-32251	36	11	such	such	ADJ
ajst-32251	36	12	as	as	ADP
ajst-32251	36	13	nanomaterials	nanomaterial	NOUN
ajst-32251	36	14	acting	act	VERB
ajst-32251	36	15	as	as	ADP
ajst-32251	36	16	electron	electron	NOUN
ajst-32251	36	17	shuttles	shuttle	NOUN
ajst-32251	36	18	.	.	PUNCT
ajst-32251	37	1	they	they	PRON
ajst-32251	37	2	transfer	transfer	VERB
ajst-32251	37	3	electrons	electron	NOUN
ajst-32251	37	4	from	from	ADP
ajst-32251	37	5	the	the	DET
ajst-32251	37	6	active	active	ADJ
ajst-32251	37	7	site	site	NOUN
ajst-32251	37	8	of	of	ADP
ajst-32251	37	9	enzymes	enzyme	NOUN
ajst-32251	37	10	—	—	PUNCT
ajst-32251	37	11	such	such	ADJ
ajst-32251	37	12	as	as	ADP
ajst-32251	37	13	glucose	glucose	NOUN
ajst-32251	37	14	oxidase	oxidase	NOUN
ajst-32251	37	15	,	,	PUNCT
ajst-32251	37	16	catalyzing	catalyze	VERB
ajst-32251	37	17	glucose	glucose	NOUN
ajst-32251	37	18	oxidation	oxidation	NOUN
ajst-32251	37	19	—	—	PUNCT
ajst-32251	37	20	to	to	ADP
ajst-32251	37	21	the	the	DET
ajst-32251	37	22	artificial	artificial	ADJ
ajst-32251	37	23	mediators	mediator	NOUN
ajst-32251	37	24	.	.	PUNCT
ajst-32251	38	1	during	during	ADP
ajst-32251	38	2	this	this	DET
ajst-32251	38	3	redox	redox	ADJ
ajst-32251	38	4	reaction	reaction	NOUN
ajst-32251	38	5	,	,	PUNCT
ajst-32251	38	6	electrons	electron	NOUN
ajst-32251	38	7	move	move	VERB
ajst-32251	38	8	from	from	ADP
ajst-32251	38	9	the	the	DET
ajst-32251	38	10	glucose	glucose	NOUN
ajst-32251	38	11	molecule	molecule	NOUN
ajst-32251	38	12	to	to	ADP
ajst-32251	38	13	the	the	DET
ajst-32251	38	14	enzyme	enzyme	NOUN
ajst-32251	38	15	and	and	CCONJ
ajst-32251	38	16	then	then	ADV
ajst-32251	38	17	to	to	ADP
ajst-32251	38	18	the	the	DET
ajst-32251	38	19	mediator	mediator	NOUN
ajst-32251	38	20	.	.	PUNCT
ajst-32251	39	1	the	the	DET
ajst-32251	39	2	electrons	electron	NOUN
ajst-32251	39	3	are	be	AUX
ajst-32251	39	4	transferred	transfer	VERB
ajst-32251	39	5	directly	directly	ADV
ajst-32251	39	6	to	to	ADP
ajst-32251	39	7	the	the	DET
ajst-32251	39	8	electrode	electrode	NOUN
ajst-32251	39	9	,	,	PUNCT
ajst-32251	39	10	generating	generate	VERB
ajst-32251	39	11	an	an	DET
ajst-32251	39	12	electrical	electrical	ADJ
ajst-32251	39	13	signal	signal	NOUN
ajst-32251	39	14	.	.	PUNCT
ajst-32251	40	1	the	the	DET
ajst-32251	40	2	current	current	ADJ
ajst-32251	40	3	produced	produce	VERB
ajst-32251	40	4	is	be	AUX
ajst-32251	40	5	proportional	proportional	ADJ
ajst-32251	40	6	to	to	ADP
ajst-32251	40	7	the	the	DET
ajst-32251	40	8	glucose	glucose	NOUN
ajst-32251	40	9	concentration	concentration	NOUN
ajst-32251	40	10	in	in	ADP
ajst-32251	40	11	the	the	DET
ajst-32251	40	12	sample	sample	NOUN
ajst-32251	40	13	.	.	PUNCT
ajst-32251	41	1	this	this	DET
ajst-32251	41	2	design	design	NOUN
ajst-32251	41	3	enhances	enhance	VERB
ajst-32251	41	4	analytical	analytical	ADJ
ajst-32251	41	5	efficiency	efficiency	NOUN
ajst-32251	41	6	,	,	PUNCT
ajst-32251	41	7	particularly	particularly	ADV
ajst-32251	41	8	regarding	regard	VERB
ajst-32251	41	9	response	response	NOUN
ajst-32251	41	10	speed	speed	NOUN
ajst-32251	41	11	and	and	CCONJ
ajst-32251	41	12	signal	signal	VERB
ajst-32251	41	13	strength.[4,5	strength.[4,5	NOUN
ajst-32251	41	14	]	]	X
ajst-32251	41	15	2.3	2.3	NUM
ajst-32251	41	16	the	the	DET
ajst-32251	41	17	third	third	ADJ
ajst-32251	41	18	-	-	PUNCT
ajst-32251	41	19	generation	generation	NOUN
ajst-32251	41	20	biosensor	biosensor	NOUN
ajst-32251	41	21	in	in	ADP
ajst-32251	41	22	the	the	DET
ajst-32251	41	23	third	third	ADJ
ajst-32251	41	24	-	-	PUNCT
ajst-32251	41	25	generation	generation	NOUN
ajst-32251	41	26	glucose	glucose	NOUN
ajst-32251	41	27	biosensors	biosensor	NOUN
ajst-32251	41	28	,	,	PUNCT
ajst-32251	41	29	a	a	DET
ajst-32251	41	30	direct	direct	ADJ
ajst-32251	41	31	electron	electron	NOUN
ajst-32251	41	32	transfer	transfer	NOUN
ajst-32251	41	33	is	be	AUX
ajst-32251	41	34	established	establish	VERB
ajst-32251	41	35	between	between	ADP
ajst-32251	41	36	the	the	DET
ajst-32251	41	37	enzyme	enzyme	NOUN
ajst-32251	41	38	and	and	CCONJ
ajst-32251	41	39	the	the	DET
ajst-32251	41	40	electrode	electrode	NOUN
ajst-32251	41	41	,	,	PUNCT
ajst-32251	41	42	eliminating	eliminate	VERB
ajst-32251	41	43	the	the	DET
ajst-32251	41	44	need	need	NOUN
ajst-32251	41	45	for	for	ADP
ajst-32251	41	46	intermediate	intermediate	ADJ
ajst-32251	41	47	electron	electron	NOUN
ajst-32251	41	48	carriers	carrier	NOUN
ajst-32251	41	49	such	such	ADJ
ajst-32251	41	50	as	as	ADP
ajst-32251	41	51	mediators	mediator	NOUN
ajst-32251	41	52	or	or	CCONJ
ajst-32251	41	53	nanomaterials	nanomaterial	NOUN
ajst-32251	41	54	.	.	PUNCT
ajst-32251	42	1	the	the	DET
ajst-32251	42	2	enzyme	enzyme	NOUN
ajst-32251	42	3	is	be	AUX
ajst-32251	42	4	immobilized	immobilize	VERB
ajst-32251	42	5	onto	onto	ADP
ajst-32251	42	6	the	the	DET
ajst-32251	42	7	electrode	electrode	NOUN
ajst-32251	42	8	surface	surface	NOUN
ajst-32251	42	9	,	,	PUNCT
ajst-32251	42	10	allowing	allow	VERB
ajst-32251	42	11	efficient	efficient	ADJ
ajst-32251	42	12	direct	direct	ADJ
ajst-32251	42	13	electron	electron	NOUN
ajst-32251	42	14	transfer	transfer	NOUN
ajst-32251	42	15	between	between	ADP
ajst-32251	42	16	the	the	DET
ajst-32251	42	17	enzyme	enzyme	NOUN
ajst-32251	42	18	’s	’s	PART
ajst-32251	42	19	active	active	ADJ
ajst-32251	42	20	site	site	NOUN
ajst-32251	42	21	and	and	CCONJ
ajst-32251	42	22	the	the	DET
ajst-32251	42	23	electrode	electrode	NOUN
ajst-32251	42	24	without	without	ADP
ajst-32251	42	25	needing	need	VERB
ajst-32251	42	26	oxygen	oxygen	NOUN
ajst-32251	42	27	or	or	CCONJ
ajst-32251	42	28	artificial	artificial	ADJ
ajst-32251	42	29	mediators	mediator	NOUN
ajst-32251	42	30	and	and	CCONJ
ajst-32251	42	31	eliminating	eliminate	VERB
ajst-32251	42	32	any	any	DET
ajst-32251	42	33	intermediate	intermediate	ADJ
ajst-32251	42	34	electron‑transfer	electron‑transfer	NOUN
ajst-32251	42	35	steps	step	NOUN
ajst-32251	42	36	.	.	PUNCT
ajst-32251	43	1	this	this	DET
ajst-32251	43	2	direct	direct	ADJ
ajst-32251	43	3	interaction	interaction	NOUN
ajst-32251	43	4	transfers	transfer	NOUN
ajst-32251	43	5	electrons	electron	NOUN
ajst-32251	43	6	straight	straight	ADV
ajst-32251	43	7	from	from	ADP
ajst-32251	43	8	the	the	DET
ajst-32251	43	9	enzyme	enzyme	NOUN
ajst-32251	43	10	’s	’s	PART
ajst-32251	43	11	active	active	ADJ
ajst-32251	43	12	site	site	NOUN
ajst-32251	43	13	to	to	ADP
ajst-32251	43	14	the	the	DET
ajst-32251	43	15	electrode	electrode	NOUN
ajst-32251	43	16	surface	surface	NOUN
ajst-32251	43	17	.	.	PUNCT
ajst-32251	44	1	this	this	DET
ajst-32251	44	2	approach	approach	NOUN
ajst-32251	44	3	improves	improve	VERB
ajst-32251	44	4	the	the	DET
ajst-32251	44	5	specificity	specificity	NOUN
ajst-32251	44	6	and	and	CCONJ
ajst-32251	44	7	stability	stability	NOUN
ajst-32251	44	8	of	of	ADP
ajst-32251	44	9	the	the	DET
ajst-32251	44	10	sensor	sensor	NOUN
ajst-32251	44	11	by	by	ADP
ajst-32251	44	12	simplifying	simplify	VERB
ajst-32251	44	13	the	the	DET
ajst-32251	44	14	electron	electron	NOUN
ajst-32251	44	15	transfer	transfer	NOUN
ajst-32251	44	16	pathway	pathway	NOUN
ajst-32251	44	17	and	and	CCONJ
ajst-32251	44	18	reducing	reduce	VERB
ajst-32251	44	19	interference	interference	NOUN
ajst-32251	44	20	from	from	ADP
ajst-32251	44	21	external	external	ADJ
ajst-32251	44	22	substances	substance	NOUN
ajst-32251	44	23	.	.	PUNCT
ajst-32251	45	1	the	the	DET
ajst-32251	45	2	design	design	NOUN
ajst-32251	45	3	often	often	ADV
ajst-32251	45	4	involves	involve	VERB
ajst-32251	45	5	modifying	modify	VERB
ajst-32251	45	6	the	the	DET
ajst-32251	45	7	electrode	electrode	NOUN
ajst-32251	45	8	surface	surface	NOUN
ajst-32251	45	9	with	with	ADP
ajst-32251	45	10	conductive	conductive	ADJ
ajst-32251	45	11	materials	material	NOUN
ajst-32251	45	12	or	or	CCONJ
ajst-32251	45	13	nanostructures	nanostructure	NOUN
ajst-32251	45	14	to	to	PART
ajst-32251	45	15	facilitate	facilitate	VERB
ajst-32251	45	16	efficient	efficient	ADJ
ajst-32251	45	17	electron	electron	NOUN
ajst-32251	45	18	tunneling	tunneling	NOUN
ajst-32251	45	19	between	between	ADP
ajst-32251	45	20	the	the	DET
ajst-32251	45	21	enzyme	enzyme	NOUN
ajst-32251	45	22	and	and	CCONJ
ajst-32251	45	23	electrode	electrode	NOUN
ajst-32251	45	24	[	[	X
ajst-32251	45	25	9,10	9,10	NUM
ajst-32251	45	26	]	]	X
ajst-32251	45	27	.	.	PUNCT
ajst-32251	46	1	2.4	2.4	NUM
ajst-32251	46	2	the	the	DET
ajst-32251	46	3	fourth	fourth	ADJ
ajst-32251	46	4	-	-	PUNCT
ajst-32251	46	5	generation	generation	NOUN
ajst-32251	46	6	biosensor	biosensor	NOUN
ajst-32251	46	7	figure	figure	NOUN
ajst-32251	46	8	3	3	NUM
ajst-32251	46	9	.	.	PUNCT
ajst-32251	47	1	this	this	DET
ajst-32251	47	2	picture	picture	NOUN
ajst-32251	47	3	illustrates	illustrate	VERB
ajst-32251	47	4	the	the	DET
ajst-32251	47	5	evolution	evolution	NOUN
ajst-32251	47	6	of	of	ADP
ajst-32251	47	7	glucose	glucose	NOUN
ajst-32251	47	8	biosensors	biosensor	NOUN
ajst-32251	47	9	from	from	ADP
ajst-32251	47	10	the	the	DET
ajst-32251	47	11	first	first	ADJ
ajst-32251	47	12	to	to	ADP
ajst-32251	47	13	the	the	DET
ajst-32251	47	14	fourth	fourth	ADJ
ajst-32251	47	15	generation	generation	NOUN
ajst-32251	47	16	.	.	PUNCT
ajst-32251	48	1	technological	technological	ADJ
ajst-32251	48	2	advancements	advancement	NOUN
ajst-32251	48	3	have	have	AUX
ajst-32251	48	4	made	make	VERB
ajst-32251	48	5	glucose	glucose	NOUN
ajst-32251	48	6	biosensors	biosensor	NOUN
ajst-32251	48	7	increasingly	increasingly	ADV
ajst-32251	48	8	efficient	efficient	ADJ
ajst-32251	48	9	,	,	PUNCT
ajst-32251	48	10	offering	offer	VERB
ajst-32251	48	11	faster	fast	ADJ
ajst-32251	48	12	response	response	NOUN
ajst-32251	48	13	times	time	NOUN
ajst-32251	48	14	and	and	CCONJ
ajst-32251	48	15	greater	great	ADJ
ajst-32251	48	16	convenience	convenience	NOUN
ajst-32251	48	17	in	in	ADP
ajst-32251	48	18	glucose	glucose	NOUN
ajst-32251	48	19	detection.[1	detection.[1	NOUN
ajst-32251	48	20	]	]	PUNCT
ajst-32251	48	21	46	46	NUM
ajst-32251	48	22	the	the	DET
ajst-32251	48	23	most	most	ADV
ajst-32251	48	24	recent	recent	ADJ
ajst-32251	48	25	development	development	NOUN
ajst-32251	48	26	in	in	ADP
ajst-32251	48	27	glucose	glucose	NOUN
ajst-32251	48	28	biosensors	biosensor	NOUN
ajst-32251	48	29	is	be	AUX
ajst-32251	48	30	the	the	DET
ajst-32251	48	31	fourth	fourth	ADJ
ajst-32251	48	32	-	-	PUNCT
ajst-32251	48	33	generation	generation	NOUN
ajst-32251	48	34	glucose	glucose	NOUN
ajst-32251	48	35	biosensor	biosensor	NOUN
ajst-32251	48	36	.	.	PUNCT
ajst-32251	49	1	ghasemi	ghasemi	PROPN
ajst-32251	49	2	et	et	PROPN
ajst-32251	49	3	al	al	PROPN
ajst-32251	49	4	.	.	PROPN
ajst-32251	49	5	presented	present	VERB
ajst-32251	49	6	a	a	DET
ajst-32251	49	7	novel	novel	ADJ
ajst-32251	49	8	non	non	ADJ
ajst-32251	49	9	-	-	ADJ
ajst-32251	49	10	enzymatic	enzymatic	ADJ
ajst-32251	49	11	glucose	glucose	NOUN
ajst-32251	49	12	sensor	sensor	NOUN
ajst-32251	49	13	type	type	NOUN
ajst-32251	49	14	,	,	PUNCT
ajst-32251	49	15	which	which	PRON
ajst-32251	49	16	significantly	significantly	ADV
ajst-32251	49	17	departs	depart	VERB
ajst-32251	49	18	from	from	ADP
ajst-32251	49	19	traditional	traditional	ADJ
ajst-32251	49	20	enzyme	enzyme	NOUN
ajst-32251	49	21	-	-	PUNCT
ajst-32251	49	22	based	base	VERB
ajst-32251	49	23	designs	design	NOUN
ajst-32251	49	24	.	.	PUNCT
ajst-32251	50	1	this	this	DET
ajst-32251	50	2	sensor	sensor	NOUN
ajst-32251	50	3	is	be	AUX
ajst-32251	50	4	based	base	VERB
ajst-32251	50	5	on	on	ADP
ajst-32251	50	6	gold	gold	NOUN
ajst-32251	50	7	–	–	PUNCT
ajst-32251	50	8	nickel	nickel	NOUN
ajst-32251	50	9	bimetallic	bimetallic	NOUN
ajst-32251	50	10	nanoparticles	nanoparticle	NOUN
ajst-32251	50	11	embedded	embed	VERB
ajst-32251	50	12	in	in	ADP
ajst-32251	50	13	an	an	DET
ajst-32251	50	14	aluminosilicate	aluminosilicate	NOUN
ajst-32251	50	15	framework	framework	NOUN
ajst-32251	50	16	,	,	PUNCT
ajst-32251	50	17	which	which	PRON
ajst-32251	50	18	was	be	AUX
ajst-32251	50	19	synthesized	synthesize	VERB
ajst-32251	50	20	from	from	ADP
ajst-32251	50	21	agricultural	agricultural	ADJ
ajst-32251	50	22	waste	waste	NOUN
ajst-32251	50	23	material	material	NOUN
ajst-32251	50	24	,	,	PUNCT
ajst-32251	50	25	making	make	VERB
ajst-32251	50	26	the	the	DET
ajst-32251	50	27	approach	approach	NOUN
ajst-32251	50	28	cost	cost	NOUN
ajst-32251	50	29	-	-	PUNCT
ajst-32251	50	30	effective	effective	ADJ
ajst-32251	50	31	and	and	CCONJ
ajst-32251	50	32	environmentally	environmentally	ADV
ajst-32251	50	33	friendly	friendly	ADJ
ajst-32251	50	34	.	.	PUNCT
ajst-32251	51	1	instead	instead	ADV
ajst-32251	51	2	of	of	ADP
ajst-32251	51	3	relying	rely	VERB
ajst-32251	51	4	on	on	ADP
ajst-32251	51	5	enzyme	enzyme	NOUN
ajst-32251	51	6	-	-	PUNCT
ajst-32251	51	7	catalyzed	catalyze	VERB
ajst-32251	51	8	redox	redox	NOUN
ajst-32251	51	9	reactions	reaction	NOUN
ajst-32251	51	10	,	,	PUNCT
ajst-32251	51	11	this	this	DET
ajst-32251	51	12	biosensor	biosensor	NOUN
ajst-32251	51	13	uses	use	VERB
ajst-32251	51	14	metallic	metallic	ADJ
ajst-32251	51	15	nanoparticles	nanoparticle	NOUN
ajst-32251	51	16	as	as	SCONJ
ajst-32251	51	17	electrocatalysts	electrocatalyst	NOUN
ajst-32251	51	18	to	to	PART
ajst-32251	51	19	oxidize	oxidize	VERB
ajst-32251	51	20	glucose	glucose	NOUN
ajst-32251	51	21	directly	directly	ADV
ajst-32251	51	22	.	.	PUNCT
ajst-32251	52	1	electrons	electron	NOUN
ajst-32251	52	2	are	be	AUX
ajst-32251	52	3	transferred	transfer	VERB
ajst-32251	52	4	directly	directly	ADV
ajst-32251	52	5	to	to	ADP
ajst-32251	52	6	the	the	DET
ajst-32251	52	7	electrode	electrode	NOUN
ajst-32251	52	8	surface	surface	NOUN
ajst-32251	52	9	through	through	ADP
ajst-32251	52	10	the	the	DET
ajst-32251	52	11	nanostructured	nanostructure	VERB
ajst-32251	52	12	material	material	NOUN
ajst-32251	52	13	,	,	PUNCT
ajst-32251	52	14	generating	generate	VERB
ajst-32251	52	15	an	an	DET
ajst-32251	52	16	electrical	electrical	ADJ
ajst-32251	52	17	signal	signal	NOUN
ajst-32251	52	18	.	.	PUNCT
ajst-32251	53	1	the	the	DET
ajst-32251	53	2	device	device	NOUN
ajst-32251	53	3	demonstrated	demonstrate	VERB
ajst-32251	53	4	a	a	DET
ajst-32251	53	5	wide	wide	ADJ
ajst-32251	53	6	linear	linear	ADJ
ajst-32251	53	7	detection	detection	NOUN
ajst-32251	53	8	range	range	NOUN
ajst-32251	53	9	and	and	CCONJ
ajst-32251	53	10	a	a	DET
ajst-32251	53	11	low	low	ADJ
ajst-32251	53	12	detection	detection	NOUN
ajst-32251	53	13	limit	limit	NOUN
ajst-32251	53	14	,	,	PUNCT
ajst-32251	53	15	key	key	ADJ
ajst-32251	53	16	indicators	indicator	NOUN
ajst-32251	53	17	of	of	ADP
ajst-32251	53	18	its	its	PRON
ajst-32251	53	19	high	high	ADJ
ajst-32251	53	20	analytical	analytical	ADJ
ajst-32251	53	21	performance	performance	NOUN
ajst-32251	53	22	.	.	PUNCT
ajst-32251	54	1	this	this	DET
ajst-32251	54	2	structure	structure	NOUN
ajst-32251	54	3	improves	improve	VERB
ajst-32251	54	4	sensitivity	sensitivity	NOUN
ajst-32251	54	5	and	and	CCONJ
ajst-32251	54	6	stability	stability	NOUN
ajst-32251	54	7	and	and	CCONJ
ajst-32251	54	8	eliminates	eliminate	VERB
ajst-32251	54	9	the	the	DET
ajst-32251	54	10	drawbacks	drawback	NOUN
ajst-32251	54	11	of	of	ADP
ajst-32251	54	12	enzyme	enzyme	NOUN
ajst-32251	54	13	degradation	degradation	NOUN
ajst-32251	54	14	and	and	CCONJ
ajst-32251	54	15	interference	interference	NOUN
ajst-32251	54	16	from	from	ADP
ajst-32251	54	17	other	other	ADJ
ajst-32251	54	18	biomolecules	biomolecule	NOUN
ajst-32251	54	19	[	[	X
ajst-32251	54	20	11	11	NUM
ajst-32251	54	21	]	]	PUNCT
ajst-32251	54	22	.	.	PUNCT
ajst-32251	55	1	3	3	X
ajst-32251	55	2	.	.	NOUN
ajst-32251	55	3	limitations	limitation	NOUN
ajst-32251	55	4	and	and	CCONJ
ajst-32251	55	5	future	future	ADJ
ajst-32251	55	6	prospects	prospect	NOUN
ajst-32251	55	7	3.1	3.1	NUM
ajst-32251	55	8	limitations	limitation	NOUN
ajst-32251	55	9	despite	despite	SCONJ
ajst-32251	55	10	the	the	DET
ajst-32251	55	11	glucose	glucose	NOUN
ajst-32251	55	12	biosensor	biosensor	NOUN
ajst-32251	55	13	's	's	PART
ajst-32251	55	14	significant	significant	ADJ
ajst-32251	55	15	process	process	NOUN
ajst-32251	55	16	improvements	improvement	NOUN
ajst-32251	55	17	over	over	ADP
ajst-32251	55	18	four	four	NUM
ajst-32251	55	19	generations	generation	NOUN
ajst-32251	55	20	,	,	PUNCT
ajst-32251	55	21	several	several	ADJ
ajst-32251	55	22	critical	critical	ADJ
ajst-32251	55	23	limitations	limitation	NOUN
ajst-32251	55	24	remain	remain	VERB
ajst-32251	55	25	unresolved	unresolved	ADJ
ajst-32251	55	26	.	.	PUNCT
ajst-32251	56	1	noninvasive	noninvasive	ADJ
ajst-32251	56	2	monitoring	monitoring	NOUN
ajst-32251	56	3	,	,	PUNCT
ajst-32251	56	4	though	though	SCONJ
ajst-32251	56	5	highly	highly	ADV
ajst-32251	56	6	attractive	attractive	ADJ
ajst-32251	56	7	,	,	PUNCT
ajst-32251	56	8	continues	continue	VERB
ajst-32251	56	9	to	to	PART
ajst-32251	56	10	face	face	VERB
ajst-32251	56	11	difficulties	difficulty	NOUN
ajst-32251	56	12	related	relate	VERB
ajst-32251	56	13	to	to	ADP
ajst-32251	56	14	measurement	measurement	NOUN
ajst-32251	56	15	accuracy	accuracy	NOUN
ajst-32251	56	16	,	,	PUNCT
ajst-32251	56	17	long	long	ADJ
ajst-32251	56	18	-	-	PUNCT
ajst-32251	56	19	term	term	NOUN
ajst-32251	56	20	stability	stability	NOUN
ajst-32251	56	21	,	,	PUNCT
ajst-32251	56	22	and	and	CCONJ
ajst-32251	56	23	user	user	NOUN
ajst-32251	56	24	comfort	comfort	NOUN
ajst-32251	56	25	.	.	PUNCT
ajst-32251	57	1	enzymebased	enzymebase	VERB
ajst-32251	57	2	sensors	sensor	NOUN
ajst-32251	57	3	,	,	PUNCT
ajst-32251	57	4	while	while	SCONJ
ajst-32251	57	5	offering	offer	VERB
ajst-32251	57	6	high	high	ADJ
ajst-32251	57	7	specificity	specificity	NOUN
ajst-32251	57	8	,	,	PUNCT
ajst-32251	57	9	are	be	AUX
ajst-32251	57	10	constrained	constrain	VERB
ajst-32251	57	11	by	by	ADP
ajst-32251	57	12	enzyme	enzyme	NOUN
ajst-32251	57	13	degradation	degradation	NOUN
ajst-32251	57	14	and	and	CCONJ
ajst-32251	57	15	interference	interference	NOUN
ajst-32251	57	16	from	from	ADP
ajst-32251	57	17	coexisting	coexist	VERB
ajst-32251	57	18	biomolecules	biomolecule	NOUN
ajst-32251	57	19	,	,	PUNCT
ajst-32251	57	20	compromising	compromise	VERB
ajst-32251	57	21	their	their	PRON
ajst-32251	57	22	durability	durability	NOUN
ajst-32251	57	23	and	and	CCONJ
ajst-32251	57	24	reliability	reliability	NOUN
ajst-32251	57	25	.	.	PUNCT
ajst-32251	58	1	these	these	DET
ajst-32251	58	2	persistent	persistent	ADJ
ajst-32251	58	3	issues	issue	NOUN
ajst-32251	58	4	indicate	indicate	VERB
ajst-32251	58	5	that	that	SCONJ
ajst-32251	58	6	future	future	ADJ
ajst-32251	58	7	sensitivity	sensitivity	NOUN
ajst-32251	58	8	,	,	PUNCT
ajst-32251	58	9	selectivity	selectivity	NOUN
ajst-32251	58	10	,	,	PUNCT
ajst-32251	58	11	and	and	CCONJ
ajst-32251	58	12	operational	operational	ADJ
ajst-32251	58	13	robustness	robustness	NOUN
ajst-32251	58	14	improvements	improvement	NOUN
ajst-32251	58	15	are	be	AUX
ajst-32251	58	16	still	still	ADV
ajst-32251	58	17	urgently	urgently	ADV
ajst-32251	58	18	required	require	VERB
ajst-32251	58	19	.	.	PUNCT
ajst-32251	59	1	3.2	3.2	NUM
ajst-32251	59	2	future	future	ADJ
ajst-32251	59	3	prospects	prospect	NOUN
ajst-32251	59	4	new	new	ADJ
ajst-32251	59	5	approaches	approach	NOUN
ajst-32251	59	6	have	have	AUX
ajst-32251	59	7	emerged	emerge	VERB
ajst-32251	59	8	to	to	PART
ajst-32251	59	9	address	address	VERB
ajst-32251	59	10	these	these	DET
ajst-32251	59	11	challenges	challenge	NOUN
ajst-32251	59	12	.	.	PUNCT
ajst-32251	60	1	for	for	ADP
ajst-32251	60	2	noninvasive	noninvasive	ADJ
ajst-32251	60	3	monitoring	monitoring	NOUN
ajst-32251	60	4	,	,	PUNCT
ajst-32251	60	5	optical	optical	ADJ
ajst-32251	60	6	or	or	CCONJ
ajst-32251	60	7	chemical	chemical	NOUN
ajst-32251	60	8	platforms	platform	NOUN
ajst-32251	60	9	based	base	VERB
ajst-32251	60	10	on	on	ADP
ajst-32251	60	11	nanomaterials	nanomaterial	NOUN
ajst-32251	60	12	can	can	AUX
ajst-32251	60	13	provide	provide	VERB
ajst-32251	60	14	higher	high	ADJ
ajst-32251	60	15	accuracy	accuracy	NOUN
ajst-32251	60	16	and	and	CCONJ
ajst-32251	60	17	stability	stability	NOUN
ajst-32251	60	18	,	,	PUNCT
ajst-32251	60	19	using	use	VERB
ajst-32251	60	20	other	other	ADJ
ajst-32251	60	21	,	,	PUNCT
ajst-32251	60	22	more	more	ADV
ajst-32251	60	23	stable	stable	ADJ
ajst-32251	60	24	and	and	CCONJ
ajst-32251	60	25	predictable	predictable	ADJ
ajst-32251	60	26	materials	material	NOUN
ajst-32251	60	27	.	.	PUNCT
ajst-32251	61	1	metal	metal	NOUN
ajst-32251	61	2	nanoparticles	nanoparticle	NOUN
ajst-32251	61	3	are	be	AUX
ajst-32251	61	4	being	be	AUX
ajst-32251	61	5	tested	test	VERB
ajst-32251	61	6	to	to	PART
ajst-32251	61	7	overcome	overcome	VERB
ajst-32251	61	8	enzymatic	enzymatic	ADJ
ajst-32251	61	9	degradation	degradation	NOUN
ajst-32251	61	10	and	and	CCONJ
ajst-32251	61	11	see	see	VERB
ajst-32251	61	12	if	if	SCONJ
ajst-32251	61	13	they	they	PRON
ajst-32251	61	14	can	can	AUX
ajst-32251	61	15	offer	offer	VERB
ajst-32251	61	16	greater	great	ADJ
ajst-32251	61	17	durability	durability	NOUN
ajst-32251	61	18	and	and	CCONJ
ajst-32251	61	19	interference	interference	NOUN
ajst-32251	61	20	resistance	resistance	NOUN
ajst-32251	61	21	.	.	PUNCT
ajst-32251	62	1	furthermore	furthermore	ADV
ajst-32251	62	2	,	,	PUNCT
ajst-32251	62	3	advances	advance	NOUN
ajst-32251	62	4	in	in	ADP
ajst-32251	62	5	microsensor	microsensor	NOUN
ajst-32251	62	6	and	and	CCONJ
ajst-32251	62	7	wireless	wireless	ADJ
ajst-32251	62	8	communication	communication	NOUN
ajst-32251	62	9	technologies	technology	NOUN
ajst-32251	62	10	transform	transform	VERB
ajst-32251	62	11	biosensors	biosensor	NOUN
ajst-32251	62	12	into	into	ADP
ajst-32251	62	13	wearable	wearable	ADJ
ajst-32251	62	14	and	and	CCONJ
ajst-32251	62	15	implantable	implantable	ADJ
ajst-32251	62	16	devices	device	NOUN
ajst-32251	62	17	,	,	PUNCT
ajst-32251	62	18	achieving	achieve	VERB
ajst-32251	62	19	greater	great	ADJ
ajst-32251	62	20	flexibility	flexibility	NOUN
ajst-32251	62	21	and	and	CCONJ
ajst-32251	62	22	enabling	enable	VERB
ajst-32251	62	23	continuous	continuous	ADJ
ajst-32251	62	24	,	,	PUNCT
ajst-32251	62	25	real	real	ADJ
ajst-32251	62	26	-	-	PUNCT
ajst-32251	62	27	time	time	NOUN
ajst-32251	62	28	blood	blood	NOUN
ajst-32251	62	29	glucose	glucose	NOUN
ajst-32251	62	30	monitoring	monitoring	NOUN
ajst-32251	62	31	.	.	PUNCT
ajst-32251	63	1	4	4	X
ajst-32251	63	2	.	.	X
ajst-32251	63	3	conclusion	conclusion	NOUN
ajst-32251	63	4	glucose	glucose	NOUN
ajst-32251	63	5	biosensors	biosensor	NOUN
ajst-32251	63	6	have	have	AUX
ajst-32251	63	7	developed	develop	VERB
ajst-32251	63	8	significantly	significantly	ADV
ajst-32251	63	9	from	from	ADP
ajst-32251	63	10	the	the	DET
ajst-32251	63	11	first	first	ADJ
ajst-32251	63	12	to	to	ADP
ajst-32251	63	13	the	the	DET
ajst-32251	63	14	fourth	fourth	ADJ
ajst-32251	63	15	generation	generation	NOUN
ajst-32251	63	16	,	,	PUNCT
ajst-32251	63	17	becoming	become	VERB
ajst-32251	63	18	increasingly	increasingly	ADV
ajst-32251	63	19	advanced	advanced	ADJ
ajst-32251	63	20	and	and	CCONJ
ajst-32251	63	21	convenient	convenient	ADJ
ajst-32251	63	22	.	.	PUNCT
ajst-32251	64	1	the	the	DET
ajst-32251	64	2	first	first	ADJ
ajst-32251	64	3	-	-	PUNCT
ajst-32251	64	4	generation	generation	NOUN
ajst-32251	64	5	sensors	sensor	NOUN
ajst-32251	64	6	had	have	VERB
ajst-32251	64	7	the	the	DET
ajst-32251	64	8	simplest	simple	ADJ
ajst-32251	64	9	structure	structure	NOUN
ajst-32251	64	10	but	but	CCONJ
ajst-32251	64	11	were	be	AUX
ajst-32251	64	12	highly	highly	ADV
ajst-32251	64	13	susceptible	susceptible	ADJ
ajst-32251	64	14	to	to	ADP
ajst-32251	64	15	oxygen	oxygen	NOUN
ajst-32251	64	16	interference	interference	NOUN
ajst-32251	64	17	,	,	PUNCT
ajst-32251	64	18	often	often	ADV
ajst-32251	64	19	leading	lead	VERB
ajst-32251	64	20	to	to	ADP
ajst-32251	64	21	inaccurate	inaccurate	ADJ
ajst-32251	64	22	measurement	measurement	NOUN
ajst-32251	64	23	results	result	NOUN
ajst-32251	64	24	.	.	PUNCT
ajst-32251	65	1	the	the	DET
ajst-32251	65	2	second	second	ADJ
ajst-32251	65	3	-	-	PUNCT
ajst-32251	65	4	generation	generation	NOUN
ajst-32251	65	5	devices	device	NOUN
ajst-32251	65	6	introduced	introduce	VERB
ajst-32251	65	7	artificial	artificial	ADJ
ajst-32251	65	8	mediators	mediator	NOUN
ajst-32251	65	9	to	to	PART
ajst-32251	65	10	replace	replace	VERB
ajst-32251	65	11	oxygen	oxygen	NOUN
ajst-32251	65	12	as	as	ADP
ajst-32251	65	13	the	the	DET
ajst-32251	65	14	electron	electron	NOUN
ajst-32251	65	15	acceptor	acceptor	NOUN
ajst-32251	65	16	.	.	PUNCT
ajst-32251	66	1	this	this	DET
ajst-32251	66	2	enhancement	enhancement	NOUN
ajst-32251	66	3	improved	improve	VERB
ajst-32251	66	4	the	the	DET
ajst-32251	66	5	stability	stability	NOUN
ajst-32251	66	6	of	of	ADP
ajst-32251	66	7	the	the	DET
ajst-32251	66	8	sensors	sensor	NOUN
ajst-32251	66	9	and	and	CCONJ
ajst-32251	66	10	allowed	allow	VERB
ajst-32251	66	11	them	they	PRON
ajst-32251	66	12	to	to	PART
ajst-32251	66	13	function	function	VERB
ajst-32251	66	14	more	more	ADV
ajst-32251	66	15	reliably	reliably	ADV
ajst-32251	66	16	under	under	ADP
ajst-32251	66	17	a	a	DET
ajst-32251	66	18	broader	broad	ADJ
ajst-32251	66	19	range	range	NOUN
ajst-32251	66	20	of	of	ADP
ajst-32251	66	21	conditions	condition	NOUN
ajst-32251	66	22	.	.	PUNCT
ajst-32251	67	1	the	the	DET
ajst-32251	67	2	third	third	ADJ
ajst-32251	67	3	-	-	PUNCT
ajst-32251	67	4	generation	generation	NOUN
ajst-32251	67	5	biosensors	biosensor	NOUN
ajst-32251	67	6	further	far	ADV
ajst-32251	67	7	advanced	advance	VERB
ajst-32251	67	8	the	the	DET
ajst-32251	67	9	technology	technology	NOUN
ajst-32251	67	10	by	by	ADP
ajst-32251	67	11	enabling	enable	VERB
ajst-32251	67	12	direct	direct	ADJ
ajst-32251	67	13	electron	electron	NOUN
ajst-32251	67	14	transfer	transfer	NOUN
ajst-32251	67	15	between	between	ADP
ajst-32251	67	16	the	the	DET
ajst-32251	67	17	enzyme	enzyme	NOUN
ajst-32251	67	18	and	and	CCONJ
ajst-32251	67	19	the	the	DET
ajst-32251	67	20	electrode	electrode	NOUN
ajst-32251	67	21	.	.	PUNCT
ajst-32251	68	1	this	this	PRON
ajst-32251	68	2	eliminated	eliminate	VERB
ajst-32251	68	3	the	the	DET
ajst-32251	68	4	need	need	NOUN
ajst-32251	68	5	for	for	ADP
ajst-32251	68	6	mediators	mediator	NOUN
ajst-32251	68	7	,	,	PUNCT
ajst-32251	68	8	increased	increase	VERB
ajst-32251	68	9	specificity	specificity	NOUN
ajst-32251	68	10	,	,	PUNCT
ajst-32251	68	11	and	and	CCONJ
ajst-32251	68	12	improved	improve	VERB
ajst-32251	68	13	the	the	DET
ajst-32251	68	14	accuracy	accuracy	NOUN
ajst-32251	68	15	of	of	ADP
ajst-32251	68	16	glucose	glucose	NOUN
ajst-32251	68	17	detection	detection	NOUN
ajst-32251	68	18	.	.	PUNCT
ajst-32251	69	1	however	however	ADV
ajst-32251	69	2	,	,	PUNCT
ajst-32251	69	3	more	more	ADV
ajst-32251	69	4	complex	complex	ADJ
ajst-32251	69	5	electrode	electrode	NOUN
ajst-32251	69	6	surface	surface	NOUN
ajst-32251	69	7	modifications	modification	NOUN
ajst-32251	69	8	were	be	AUX
ajst-32251	69	9	required	require	VERB
ajst-32251	69	10	to	to	PART
ajst-32251	69	11	ensure	ensure	VERB
ajst-32251	69	12	effective	effective	ADJ
ajst-32251	69	13	electron	electron	NOUN
ajst-32251	69	14	transfer	transfer	NOUN
ajst-32251	69	15	.	.	PUNCT
ajst-32251	70	1	most	most	ADV
ajst-32251	70	2	recently	recently	ADV
ajst-32251	70	3	,	,	PUNCT
ajst-32251	70	4	fourthgeneration	fourthgeneration	NOUN
ajst-32251	70	5	glucose	glucose	NOUN
ajst-32251	70	6	biosensors	biosensor	NOUN
ajst-32251	70	7	have	have	AUX
ajst-32251	70	8	moved	move	VERB
ajst-32251	70	9	away	away	ADV
ajst-32251	70	10	from	from	ADP
ajst-32251	70	11	enzymatic	enzymatic	ADJ
ajst-32251	70	12	systems	system	NOUN
ajst-32251	70	13	entirely	entirely	ADV
ajst-32251	70	14	.	.	PUNCT
ajst-32251	71	1	these	these	DET
ajst-32251	71	2	nonenzymatic	nonenzymatic	ADJ
ajst-32251	71	3	sensors	sensor	NOUN
ajst-32251	71	4	utilize	utilize	VERB
ajst-32251	71	5	metal	metal	NOUN
ajst-32251	71	6	nanoparticles	nanoparticle	NOUN
ajst-32251	71	7	as	as	ADP
ajst-32251	71	8	catalysts	catalyst	NOUN
ajst-32251	71	9	,	,	PUNCT
ajst-32251	71	10	offering	offer	VERB
ajst-32251	71	11	high	high	ADJ
ajst-32251	71	12	stability	stability	NOUN
ajst-32251	71	13	,	,	PUNCT
ajst-32251	71	14	low	low	ADJ
ajst-32251	71	15	production	production	NOUN
ajst-32251	71	16	cost	cost	NOUN
ajst-32251	71	17	,	,	PUNCT
ajst-32251	71	18	and	and	CCONJ
ajst-32251	71	19	the	the	DET
ajst-32251	71	20	ability	ability	NOUN
ajst-32251	71	21	to	to	PART
ajst-32251	71	22	operate	operate	VERB
ajst-32251	71	23	without	without	ADP
ajst-32251	71	24	biological	biological	ADJ
ajst-32251	71	25	enzymes	enzyme	NOUN
ajst-32251	71	26	.	.	PUNCT
ajst-32251	72	1	as	as	ADP
ajst-32251	72	2	a	a	DET
ajst-32251	72	3	result	result	NOUN
ajst-32251	72	4	,	,	PUNCT
ajst-32251	72	5	they	they	PRON
ajst-32251	72	6	are	be	AUX
ajst-32251	72	7	well	well	ADV
ajst-32251	72	8	-	-	PUNCT
ajst-32251	72	9	suited	suit	VERB
ajst-32251	72	10	for	for	ADP
ajst-32251	72	11	industrial	industrial	ADJ
ajst-32251	72	12	applications	application	NOUN
ajst-32251	72	13	and	and	CCONJ
ajst-32251	72	14	harsh	harsh	ADJ
ajst-32251	72	15	environmental	environmental	ADJ
ajst-32251	72	16	conditions	condition	NOUN
ajst-32251	72	17	,	,	PUNCT
ajst-32251	72	18	where	where	SCONJ
ajst-32251	72	19	traditional	traditional	ADJ
ajst-32251	72	20	enzyme	enzyme	NOUN
ajst-32251	72	21	-	-	PUNCT
ajst-32251	72	22	based	base	VERB
ajst-32251	72	23	sensors	sensor	NOUN
ajst-32251	72	24	may	may	AUX
ajst-32251	72	25	fail	fail	VERB
ajst-32251	72	26	.	.	PUNCT
ajst-32251	73	1	as	as	SCONJ
ajst-32251	73	2	glucose	glucose	NOUN
ajst-32251	73	3	biosensors	biosensor	NOUN
ajst-32251	73	4	continue	continue	VERB
ajst-32251	73	5	to	to	PART
ajst-32251	73	6	develop	develop	VERB
ajst-32251	73	7	,	,	PUNCT
ajst-32251	73	8	future	future	ADJ
ajst-32251	73	9	research	research	NOUN
ajst-32251	73	10	will	will	AUX
ajst-32251	73	11	focus	focus	VERB
ajst-32251	73	12	on	on	ADP
ajst-32251	73	13	improving	improve	VERB
ajst-32251	73	14	their	their	PRON
ajst-32251	73	15	measurement	measurement	NOUN
ajst-32251	73	16	accuracy	accuracy	NOUN
ajst-32251	73	17	,	,	PUNCT
ajst-32251	73	18	making	make	VERB
ajst-32251	73	19	them	they	PRON
ajst-32251	73	20	more	more	ADV
ajst-32251	73	21	compact	compact	ADJ
ajst-32251	73	22	,	,	PUNCT
ajst-32251	73	23	and	and	CCONJ
ajst-32251	73	24	enabling	enable	VERB
ajst-32251	73	25	them	they	PRON
ajst-32251	73	26	to	to	PART
ajst-32251	73	27	connect	connect	VERB
ajst-32251	73	28	to	to	ADP
ajst-32251	73	29	phones	phone	NOUN
ajst-32251	73	30	.	.	PUNCT
ajst-32251	74	1	one	one	NUM
ajst-32251	74	2	of	of	ADP
ajst-32251	74	3	the	the	DET
ajst-32251	74	4	most	most	ADV
ajst-32251	74	5	critical	critical	ADJ
ajst-32251	74	6	areas	area	NOUN
ajst-32251	74	7	is	be	AUX
ajst-32251	74	8	the	the	DET
ajst-32251	74	9	possibility	possibility	NOUN
ajst-32251	74	10	of	of	ADP
ajst-32251	74	11	making	make	VERB
ajst-32251	74	12	glucose	glucose	NOUN
ajst-32251	74	13	biosensors	biosensor	NOUN
ajst-32251	74	14	wearable	wearable	ADJ
ajst-32251	74	15	or	or	CCONJ
ajst-32251	74	16	implantable	implantable	ADJ
ajst-32251	74	17	.	.	PUNCT
ajst-32251	75	1	this	this	DET
ajst-32251	75	2	47	47	NUM
ajst-32251	75	3	will	will	AUX
ajst-32251	75	4	allow	allow	VERB
ajst-32251	75	5	more	more	ADV
ajst-32251	75	6	detailed	detailed	ADJ
ajst-32251	75	7	and	and	CCONJ
ajst-32251	75	8	real	real	ADJ
ajst-32251	75	9	-	-	PUNCT
ajst-32251	75	10	time	time	NOUN
ajst-32251	75	11	monitoring	monitoring	NOUN
ajst-32251	75	12	of	of	ADP
ajst-32251	75	13	diabetic	diabetic	ADJ
ajst-32251	75	14	patients	patient	NOUN
ajst-32251	75	15	,	,	PUNCT
ajst-32251	75	16	and	and	CCONJ
ajst-32251	75	17	there	there	PRON
ajst-32251	75	18	is	be	VERB
ajst-32251	75	19	hope	hope	NOUN
ajst-32251	75	20	for	for	ADP
ajst-32251	75	21	noninvasive	noninvasive	ADJ
ajst-32251	75	22	use	use	NOUN
ajst-32251	75	23	.	.	PUNCT
ajst-32251	76	1	references	reference	NOUN
ajst-32251	76	2	[	[	X
ajst-32251	76	3	1	1	X
ajst-32251	76	4	]	]	PUNCT
ajst-32251	76	5	a	a	DET
ajst-32251	76	6	review	review	NOUN
ajst-32251	76	7	on	on	ADP
ajst-32251	76	8	biosensors	biosensor	NOUN
ajst-32251	76	9	and	and	CCONJ
ajst-32251	76	10	recent	recent	ADJ
ajst-32251	76	11	development	development	NOUN
ajst-32251	76	12	of	of	ADP
ajst-32251	76	13	nanostructured	nanostructure	VERB
ajst-32251	76	14	materials	material	NOUN
ajst-32251	76	15	-	-	PUNCT
ajst-32251	76	16	enabled	enable	VERB
ajst-32251	76	17	biosensors	biosensor	NOUN
ajst-32251	76	18	sensors	sensor	NOUN
ajst-32251	76	19	2021	2021	NUM
ajst-32251	76	20	,	,	PUNCT
ajst-32251	76	21	21	21	NUM
ajst-32251	76	22	,	,	PUNCT
ajst-32251	76	23	1109.https://doiorg/10.3390	1109.https://doiorg/10.3390	NUM
ajst-32251	76	24	/	/	SYM
ajst-32251	76	25	s21041109	s21041109	VERB
ajst-32251	76	26	[	[	X
ajst-32251	76	27	2	2	NUM
ajst-32251	76	28	]	]	PUNCT
ajst-32251	76	29	bhalla	bhalla	NOUN
ajst-32251	76	30	,	,	PUNCT
ajst-32251	76	31	n.	n.	NOUN
ajst-32251	76	32	;	;	PUNCT
ajst-32251	76	33	jolly	jolly	ADV
ajst-32251	76	34	,	,	PUNCT
ajst-32251	76	35	p.	p.	NOUN
ajst-32251	76	36	;	;	PUNCT
ajst-32251	76	37	formisano	formisano	PROPN
ajst-32251	76	38	,	,	PUNCT
ajst-32251	76	39	n.	n.	NOUN
ajst-32251	76	40	;	;	PUNCT
ajst-32251	76	41	estrela	estrela	PROPN
ajst-32251	76	42	,	,	PUNCT
ajst-32251	76	43	p.	p.	NOUN
ajst-32251	76	44	introduction	introduction	NOUN
ajst-32251	76	45	to	to	ADP
ajst-32251	76	46	biosensors	biosensor	NOUN
ajst-32251	76	47	.	.	PUNCT
ajst-32251	77	1	essays	essays	PROPN
ajst-32251	77	2	biochem	biochem	PROPN
ajst-32251	77	3	.	.	PUNCT
ajst-32251	78	1	2016	2016	NUM
ajst-32251	78	2	,	,	PUNCT
ajst-32251	78	3	60	60	NUM
ajst-32251	78	4	,	,	PUNCT
ajst-32251	78	5	1	1	NUM
ajst-32251	78	6	–	–	PUNCT
ajst-32251	78	7	8	8	NUM
ajst-32251	78	8	.	.	PUNCT
ajst-32251	79	1	[	[	X
ajst-32251	79	2	3	3	NUM
ajst-32251	79	3	]	]	X
ajst-32251	79	4	clark	clark	NOUN
ajst-32251	79	5	,	,	PUNCT
ajst-32251	79	6	l.c	l.c	PROPN
ajst-32251	79	7	.	.	PROPN
ajst-32251	79	8	&	&	CCONJ
ajst-32251	79	9	lyons	lyons	PROPN
ajst-32251	79	10	,	,	PUNCT
ajst-32251	79	11	c.	c.	PROPN
ajst-32251	79	12	(	(	PUNCT
ajst-32251	79	13	1962	1962	NUM
ajst-32251	79	14	)	)	PUNCT
ajst-32251	79	15	.	.	PUNCT
ajst-32251	80	1	electrode	electrode	NOUN
ajst-32251	80	2	systems	system	NOUN
ajst-32251	80	3	for	for	ADP
ajst-32251	80	4	continuous	continuous	ADJ
ajst-32251	80	5	monitoring	monitoring	NOUN
ajst-32251	80	6	in	in	ADP
ajst-32251	80	7	cardiovascular	cardiovascular	ADJ
ajst-32251	80	8	surgery	surgery	NOUN
ajst-32251	80	9	.	.	PUNCT
ajst-32251	81	1	annals	annal	NOUN
ajst-32251	81	2	of	of	ADP
ajst-32251	81	3	the	the	DET
ajst-32251	81	4	new	new	PROPN
ajst-32251	81	5	york	york	PROPN
ajst-32251	81	6	academy	academy	PROPN
ajst-32251	81	7	of	of	ADP
ajst-32251	81	8	sciences	sciences	PROPN
ajst-32251	81	9	,	,	PUNCT
ajst-32251	81	10	102(1	102(1	NUM
ajst-32251	81	11	)	)	PUNCT
ajst-32251	81	12	,	,	PUNCT
ajst-32251	81	13	29–45	29–45	NUM
ajst-32251	81	14	.	.	PUNCT
ajst-32251	82	1	[	[	X
ajst-32251	82	2	4	4	NUM
ajst-32251	82	3	]	]	PUNCT
ajst-32251	82	4	clemens	clemen	NOUN
ajst-32251	82	5	,	,	PUNCT
ajst-32251	82	6	a.h	a.h	PROPN
ajst-32251	82	7	.	.	PROPN
ajst-32251	82	8	;	;	PUNCT
ajst-32251	82	9	chang	chang	PROPN
ajst-32251	82	10	,	,	PUNCT
ajst-32251	82	11	p.h	p.h	PROPN
ajst-32251	82	12	.	.	PROPN
ajst-32251	82	13	;	;	PUNCT
ajst-32251	82	14	myers	myers	PROPN
ajst-32251	82	15	,	,	PUNCT
ajst-32251	82	16	r.w	r.w	PROPN
ajst-32251	82	17	.	.	PROPN
ajst-32251	82	18	le	le	PROPN
ajst-32251	82	19	développement	développement	PROPN
ajst-32251	82	20	d’un	d’un	PROPN
ajst-32251	82	21	système	système	PROPN
ajst-32251	82	22	automatique	automatique	PROPN
ajst-32251	82	23	d’infusion	d’infusion	PROPN
ajst-32251	82	24	d’insuline	d’insuline	ADP
ajst-32251	82	25	controle	controle	ADJ
ajst-32251	82	26	par	par	NOUN
ajst-32251	82	27	laglycemie	laglycemie	PROPN
ajst-32251	82	28	,	,	PUNCT
ajst-32251	82	29	son	son	NOUN
ajst-32251	82	30	système	système	PROPN
ajst-32251	82	31	de	de	PROPN
ajst-32251	82	32	dosage	dosage	NOUN
ajst-32251	82	33	du	du	NOUN
ajst-32251	82	34	glucose	glucose	NOUN
ajst-32251	82	35	et	et	NOUN
ajst-32251	82	36	ses	se	VERB
ajst-32251	82	37	algorithmes	algorithme	NOUN
ajst-32251	82	38	de	de	PROPN
ajst-32251	82	39	controle	controle	PROPN
ajst-32251	82	40	.	.	PUNCT
ajst-32251	83	1	journ	journ	PROPN
ajst-32251	83	2	.	.	PUNCT
ajst-32251	84	1	annu	annu	NOUN
ajst-32251	84	2	.	.	PUNCT
ajst-32251	85	1	diabétol	diabétol	NOUN
ajst-32251	85	2	.	.	PUNCT
ajst-32251	86	1	hotel	hotel	NOUN
ajst-32251	86	2	dieu	dieu	PROPN
ajst-32251	86	3	1976	1976	NUM
ajst-32251	86	4	,	,	PUNCT
ajst-32251	86	5	269–278	269–278	NUM
ajst-32251	86	6	.	.	PUNCT
ajst-32251	87	1	[	[	X
ajst-32251	87	2	5	5	NUM
ajst-32251	87	3	]	]	PUNCT
ajst-32251	87	4	clemens	clemen	NOUN
ajst-32251	87	5	,	,	PUNCT
ajst-32251	87	6	a.h	a.h	PROPN
ajst-32251	87	7	.	.	PROPN
ajst-32251	87	8	;	;	PUNCT
ajst-32251	87	9	chang	chang	PROPN
ajst-32251	87	10	,	,	PUNCT
ajst-32251	87	11	p.h	p.h	PROPN
ajst-32251	87	12	.	.	PROPN
ajst-32251	87	13	;	;	PUNCT
ajst-32251	87	14	myers	myers	PROPN
ajst-32251	87	15	,	,	PUNCT
ajst-32251	87	16	r.w	r.w	PROPN
ajst-32251	87	17	.	.	PUNCT
ajst-32251	87	18	the	the	DET
ajst-32251	87	19	development	development	NOUN
ajst-32251	87	20	of	of	ADP
ajst-32251	87	21	biostator	biostator	NOUN
ajst-32251	87	22	,	,	PUNCT
ajst-32251	87	23	a	a	DET
ajst-32251	87	24	glucose	glucose	NOUN
ajst-32251	87	25	controller	controller	NOUN
ajst-32251	87	26	insulin	insulin	NOUN
ajst-32251	87	27	infusion	infusion	NOUN
ajst-32251	87	28	system	system	NOUN
ajst-32251	87	29	(	(	PUNCT
ajst-32251	87	30	gciis	gciis	NOUN
ajst-32251	87	31	)	)	PUNCT
ajst-32251	87	32	.	.	PUNCT
ajst-32251	88	1	horm	horm	NOUN
ajst-32251	88	2	.	.	PUNCT
ajst-32251	89	1	metab	metab	PROPN
ajst-32251	89	2	.	.	PUNCT
ajst-32251	90	1	res	re	NOUN
ajst-32251	90	2	.	.	PUNCT
ajst-32251	91	1	suppl	suppl	PROPN
ajst-32251	91	2	.	.	PUNCT
ajst-32251	92	1	1977	1977	NUM
ajst-32251	92	2	,	,	PUNCT
ajst-32251	92	3	7	7	NUM
ajst-32251	92	4	,	,	PUNCT
ajst-32251	92	5	22–23	22–23	NUM
ajst-32251	92	6	.	.	PUNCT
ajst-32251	93	1	[	[	X
ajst-32251	93	2	6	6	NUM
ajst-32251	93	3	]	]	PUNCT
ajst-32251	93	4	geyssant	geyssant	NOUN
ajst-32251	93	5	,	,	PUNCT
ajst-32251	93	6	a.	a.	NOUN
ajst-32251	93	7	;	;	PUNCT
ajst-32251	93	8	dormois	dormois	PROPN
ajst-32251	93	9	,	,	PUNCT
ajst-32251	93	10	d.	d.	PROPN
ajst-32251	93	11	;	;	PUNCT
ajst-32251	93	12	barthelemy	barthelemy	PROPN
ajst-32251	93	13	,	,	PUNCT
ajst-32251	93	14	j.c	j.c	PROPN
ajst-32251	93	15	.	.	PROPN
ajst-32251	93	16	;	;	PUNCT
ajst-32251	93	17	lacour	lacour	PROPN
ajst-32251	93	18	,	,	PUNCT
ajst-32251	93	19	j.r	j.r	PROPN
ajst-32251	93	20	.	.	PROPN
ajst-32251	93	21	lactate	lactate	PROPN
ajst-32251	93	22	determination	determination	NOUN
ajst-32251	93	23	with	with	ADP
ajst-32251	93	24	the	the	DET
ajst-32251	93	25	lactate	lactate	NOUN
ajst-32251	93	26	analyser	analyser	NOUN
ajst-32251	93	27	la	la	NOUN
ajst-32251	93	28	640	640	NUM
ajst-32251	93	29	:	:	PUNCT
ajst-32251	93	30	a	a	DET
ajst-32251	93	31	critical	critical	ADJ
ajst-32251	93	32	study.scand	study.scand	NOUN
ajst-32251	93	33	.	.	PUNCT
ajst-32251	93	34	j.	j.	PROPN
ajst-32251	93	35	clin	clin	PROPN
ajst-32251	93	36	.	.	PUNCT
ajst-32251	94	1	lab	lab	PROPN
ajst-32251	94	2	.	.	PUNCT
ajst-32251	94	3	investig	investig	PROPN
ajst-32251	94	4	.	.	PROPN
ajst-32251	94	5	1985	1985	NUM
ajst-32251	94	6	,	,	PUNCT
ajst-32251	94	7	45	45	NUM
ajst-32251	94	8	,	,	PUNCT
ajst-32251	94	9	145–149	145–149	NUM
ajst-32251	94	10	.	.	PUNCT
ajst-32251	95	1	[	[	X
ajst-32251	95	2	7	7	NUM
ajst-32251	95	3	]	]	X
ajst-32251	95	4	heineman	heineman	NOUN
ajst-32251	95	5	,	,	PUNCT
ajst-32251	95	6	w.r	w.r	PROPN
ajst-32251	95	7	.	.	PROPN
ajst-32251	95	8	;	;	PUNCT
ajst-32251	95	9	jensen	jensen	PROPN
ajst-32251	95	10	,	,	PUNCT
ajst-32251	95	11	w.b	w.b	PROPN
ajst-32251	95	12	.	.	PROPN
ajst-32251	95	13	leland	leland	PROPN
ajst-32251	95	14	c.	c.	PROPN
ajst-32251	95	15	clark	clark	PROPN
ajst-32251	95	16	jr	jr	PROPN
ajst-32251	95	17	.	.	PROPN
ajst-32251	96	1	(	(	PUNCT
ajst-32251	96	2	1918–2005	1918–2005	NUM
ajst-32251	96	3	)	)	PUNCT
ajst-32251	96	4	.	.	PUNCT
ajst-32251	97	1	biosens	biosen	NOUN
ajst-32251	97	2	.	.	PUNCT
ajst-32251	98	1	bioelectron	bioelectron	PROPN
ajst-32251	98	2	.	.	PUNCT
ajst-32251	99	1	2006	2006	NUM
ajst-32251	99	2	,	,	PUNCT
ajst-32251	99	3	21	21	NUM
ajst-32251	99	4	,	,	PUNCT
ajst-32251	99	5	1403	1403	NUM
ajst-32251	99	6	–	–	PUNCT
ajst-32251	99	7	1404	1404	NUM
ajst-32251	99	8	.	.	PUNCT
ajst-32251	100	1	[	[	X
ajst-32251	100	2	8	8	NUM
ajst-32251	100	3	]	]	SYM
ajst-32251	100	4	clark	clark	NOUN
ajst-32251	100	5	,	,	PUNCT
ajst-32251	100	6	l.c	l.c	PROPN
ajst-32251	100	7	.	.	PROPN
ajst-32251	100	8	;	;	PUNCT
ajst-32251	100	9	lyons	lyons	PROPN
ajst-32251	100	10	,	,	PUNCT
ajst-32251	100	11	c.	c.	PROPN
ajst-32251	100	12	electrode	electrode	NOUN
ajst-32251	100	13	systems	system	NOUN
ajst-32251	100	14	for	for	ADP
ajst-32251	100	15	continuous	continuous	ADJ
ajst-32251	100	16	monitoring	monitoring	NOUN
ajst-32251	100	17	in	in	ADP
ajst-32251	100	18	cardiovascular	cardiovascular	ADJ
ajst-32251	100	19	surgery	surgery	NOUN
ajst-32251	100	20	.	.	PUNCT
ajst-32251	101	1	ann	ann	PROPN
ajst-32251	101	2	.	.	PUNCT
ajst-32251	101	3	n.	n.	PROPN
ajst-32251	101	4	y.	y.	PROPN
ajst-32251	101	5	acad	acad	PROPN
ajst-32251	101	6	.	.	PUNCT
ajst-32251	102	1	sci	sci	PROPN
ajst-32251	102	2	.	.	PROPN
ajst-32251	102	3	1962	1962	NUM
ajst-32251	102	4	,	,	PUNCT
ajst-32251	102	5	102	102	NUM
ajst-32251	102	6	,	,	PUNCT
ajst-32251	102	7	29–45	29–45	NUM
ajst-32251	102	8	.	.	PUNCT
ajst-32251	103	1	[	[	X
ajst-32251	103	2	9	9	NUM
ajst-32251	103	3	]	]	X
ajst-32251	103	4	wang	wang	PROPN
ajst-32251	103	5	,	,	PUNCT
ajst-32251	103	6	j.	j.	PROPN
ajst-32251	103	7	(	(	PUNCT
ajst-32251	103	8	2008	2008	NUM
ajst-32251	103	9	)	)	PUNCT
ajst-32251	103	10	.	.	PUNCT
ajst-32251	104	1	electrochemical	electrochemical	ADJ
ajst-32251	104	2	glucose	glucose	NOUN
ajst-32251	104	3	biosensors	biosensor	NOUN
ajst-32251	104	4	.	.	PUNCT
ajst-32251	105	1	chemical	chemical	ADJ
ajst-32251	105	2	reviews	review	NOUN
ajst-32251	105	3	,	,	PUNCT
ajst-32251	105	4	108(2	108(2	NUM
ajst-32251	105	5	)	)	PUNCT
ajst-32251	105	6	,	,	PUNCT
ajst-32251	105	7	814–825	814–825	NUM
ajst-32251	105	8	.	.	PUNCT
ajst-32251	106	1	https://	https://	PROPN
ajst-32251	106	2	doi	doi	PROPN
ajst-32251	106	3	.	.	PUNCT
ajst-32251	106	4	org/10.1021	org/10.1021	NOUN
ajst-32251	106	5	/	/	SYM
ajst-32251	106	6	cr068123a	cr068123a	NOUN
ajst-32251	106	7	[	[	X
ajst-32251	106	8	10	10	NUM
ajst-32251	106	9	]	]	X
ajst-32251	106	10	suzuki	suzuki	PROPN
ajst-32251	106	11	,	,	PUNCT
ajst-32251	106	12	k.	k.	PROPN
ajst-32251	106	13	,	,	PUNCT
ajst-32251	106	14	shiroishi	shiroishi	PROPN
ajst-32251	106	15	,	,	PUNCT
ajst-32251	106	16	h.	h.	PROPN
ajst-32251	106	17	,	,	PUNCT
ajst-32251	106	18	yoshida	yoshida	PROPN
ajst-32251	106	19	,	,	PUNCT
ajst-32251	106	20	m.	m.	NOUN
ajst-32251	106	21	,	,	PUNCT
ajst-32251	106	22	&	&	CCONJ
ajst-32251	106	23	sode	sode	PROPN
ajst-32251	106	24	,	,	PUNCT
ajst-32251	106	25	k.	k.	PROPN
ajst-32251	106	26	(	(	PUNCT
ajst-32251	106	27	2020	2020	NUM
ajst-32251	106	28	)	)	PUNCT
ajst-32251	106	29	.	.	PUNCT
ajst-32251	107	1	engineered	engineer	VERB
ajst-32251	107	2	glucose	glucose	NOUN
ajst-32251	107	3	oxidase	oxidase	NOUN
ajst-32251	107	4	capable	capable	ADJ
ajst-32251	107	5	of	of	ADP
ajst-32251	107	6	quasidirect	quasidirect	ADJ
ajst-32251	107	7	electron	electron	NOUN
ajst-32251	107	8	transfer	transfer	NOUN
ajst-32251	107	9	.	.	PUNCT
ajst-32251	108	1	international	international	ADJ
ajst-32251	108	2	journal	journal	NOUN
ajst-32251	108	3	of	of	ADP
ajst-32251	108	4	molecular	molecular	ADJ
ajst-32251	108	5	sciences	science	NOUN
ajst-32251	108	6	,	,	PUNCT
ajst-32251	108	7	21(3	21(3	NUM
ajst-32251	108	8	)	)	PUNCT
ajst-32251	108	9	,	,	PUNCT
ajst-32251	108	10	1137	1137	NUM
ajst-32251	108	11	.	.	PUNCT
ajst-32251	109	1	https://	https://	NOUN
ajst-32251	109	2	doi.org/	doi.org/	ADV
ajst-32251	109	3	10	10	NUM
ajst-32251	109	4	.	.	PUNCT
ajst-32251	110	1	3390/	3390/	NUM
ajst-32251	110	2	ijms21031137	ijms21031137	PROPN
ajst-32251	110	3	[	[	X
ajst-32251	110	4	11	11	NUM
ajst-32251	110	5	]	]	SYM
ajst-32251	110	6	amiripour	amiripour	ADJ
ajst-32251	110	7	,	,	PUNCT
ajst-32251	110	8	f.p	f.p	PROPN
ajst-32251	110	9	.	.	PROPN
ajst-32251	110	10	;	;	PUNCT
ajst-32251	110	11	ghasemi	ghasemi	PROPN
ajst-32251	110	12	,	,	PUNCT
ajst-32251	110	13	s.	s.	PROPN
ajst-32251	110	14	;	;	PUNCT
ajst-32251	110	15	azizi	azizi	PROPN
ajst-32251	110	16	,	,	PUNCT
ajst-32251	110	17	s.n	s.n	PROPN
ajst-32251	110	18	.	.	PROPN
ajst-32251	110	19	a	a	DET
ajst-32251	110	20	novel	novel	ADJ
ajst-32251	110	21	non	non	ADJ
ajst-32251	110	22	-	-	ADJ
ajst-32251	110	23	enzymatic	enzymatic	ADJ
ajst-32251	110	24	glucose	glucose	NOUN
ajst-32251	110	25	sensor	sensor	NOUN
ajst-32251	110	26	based	base	VERB
ajst-32251	110	27	on	on	ADP
ajst-32251	110	28	gold	gold	NOUN
ajst-32251	110	29	-	-	PUNCT
ajst-32251	110	30	nickel	nickel	NOUN
ajst-32251	110	31	bimetallic	bimetallic	NOUN
ajst-32251	110	32	nanoparticles	nanoparticle	NOUN
ajst-32251	110	33	doped	dope	VERB
ajst-32251	110	34	aluminosilicate	aluminosilicate	NOUN
ajst-32251	110	35	framework	framework	NOUN
ajst-32251	110	36	prepared	prepare	VERB
ajst-32251	110	37	from	from	ADP
ajst-32251	110	38	agro	agro	ADJ
ajst-32251	110	39	-	-	PUNCT
ajst-32251	110	40	waste	waste	NOUN
ajst-32251	110	41	material	material	NOUN
ajst-32251	110	42	.	.	PUNCT
ajst-32251	111	1	appl	appl	PROPN
ajst-32251	111	2	.	.	PUNCT
ajst-32251	112	1	surf	surf	PROPN
ajst-32251	112	2	.	.	PUNCT
ajst-32251	113	1	sci	sci	PROPN
ajst-32251	113	2	.	.	PROPN
ajst-32251	113	3	2021	2021	NUM
ajst-32251	113	4	,	,	PUNCT
ajst-32251	113	5	537	537	NUM
ajst-32251	113	6	,	,	PUNCT
ajst-32251	113	7	147827	147827	NUM
ajst-32251	113	8	.	.	PUNCT