ACTA BOT. CROAT. 77 (1), 2018 S3 In memoriam Professor Kroata Hazler Pilepić (1968–2017) Professor Kroata Hazler Pilepić, PhD, a Croatian scientist and full professor employed at the Faculty of Pharmacy and Bio- chemistry, University of Zagreb, died on September 1, 2017. Kroata was born on Novem- ber 23, 1968 in Zagreb (Croa- tia), where she finished elemen- tary school, music school (piano) and high school (pharmacy tech- nician). In 1992 she finished the graduate course of pharmacy at the Faculty of Pharmacy and Biochemistry, University of Zagreb. She gained her master's degree from the postgradu- ate school of natural sciences (field: biology – molecular and cell biology) at the Faculty of Science, University of Zagreb in 1997. In 2003, she gained her doctoral degree from the Faculty of Science, University of Zagreb. From 1992 to 2004 she worked as an assistant at the Department of Pharmaceu- tical Botany at the Faculty of Pharmacy and Biochemistry, University of Zagreb, after which she was appointed senior research assistant (2004), assistant professor (2007), associ- ate professor (2011) and full professor (2017) at the same Department. She participated in teaching the graduate courses Phar- maceutical Botany (1992–2017) and Cell Biology with Ge- netics (1992–1998, 2013) at the Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia, and further- more, the graduate course Pharmaceutical Botany at the Faculty of Chemistry and Technology, University of Split, Croatia (2004–2006) and the Faculty of Pharmacy, Univer- sity of Mostar, Bosnia and Herzegovina (2012). Finally, she taught the graduate course Medicinal Plants at the Faculty of Forestry, University of Zagreb, Croatia (2007–2017). She was author and co-author of two chapters in a university text- book, author of two pharmaceutical botany handbooks and a mentor of 85 graduate students and one doctoral student. Kroata’s scientific interests included plant population genetics, molecular phylogeny and systematics, functional genomics, plant biochemistry, morpho-anatomical char- acteristics of plants, secondary plant metabolites and their biological effects. She was particularly interested in species from the genus Hypericum L. During her master’s studies, through intensive field work, under the supervision of Pro- fessor Ivan Šugar from the Department of Pharmaceutical Botany, Faculty of Pharmacy and Biochemistry, University of Zagreb, she gained a vast knowledge of botany and phy- tocoenology and expanded her knowledge of morpho-an- atomical plant characteristics, plant physiology, secondary metabolites and their biological effects. She received addi- tional scientific training at the Department of Plant Ecology, University of Bordeaux I, Talence, France during 1995 and 1996, where she perfected her botanical knowledge, appli- cation of isoenzymes as molecular markers and methods of plant population genetics. She had further training in plant biology, molecular phylogeny and plant systematics at the Division of Molecular Biology of the Ruđer Bošković Insti- tute in Zagreb, where she conducted research for her doc- toral thesis. The latter was largely financed by funds from her project for young researchers, funded by the Ministry of Sci- ence, Education and Sports of the Republic of Croatia. After- wards, she continued her scientific development in function- al genomics and plant biochemistry, working on a project of Professor Hrvoje Fulgosi at the Laboratory for Electron Mi- croscopy of the Ruđer Bošković Institute. She herself was also the head of five projects funded by the University of Zagreb and one project funded by the Foundation of the Croatian Academy of Sciences and Arts, and was an associate on five projects funded by the Ministry of Science, Education and Sports of the Republic of Croatia, as well as on the Croatian- French scientific program of integral actions called Cogito. She published 36 scientific papers and participated with oral and/or poster presentations in about 40 scientific meetings and was a member of the organisation committee of the 1st Croatian Congress on Molecular Life Sciences. She was al- so a co-author of one professional book and author and co- author of several professional papers and popular science articles. Moreover, she gave many professional lectures and workshops and was the creator of two interactive exhibitions that popularize science. She was a member (1992–2017) and a vice president (2001–2008) of the Croatian Society of Plant Biology, as well as a member of the Federation of European Societies of Plant Biology (1992–2017), Croatian Genetic Society (1995– 2017), Iris croatica Society (2004–2017) and Croatian Bo- tanical Society (2009–2017). She was also a member of the Recognition of Foreign Professional Qualifications Commis- sion at the Croatian Chamber of Pharmacists (2015–2017). At the Faculty of Pharmacy and Biochemistry she held the following positions: member of the Education Committee S4 ACTA BOT. CROAT. 77 (1), 2018 (2010–2014), president of the Student Papers and Awards Committee (2015–2016), member of the Awards and Hon- ours Committee (2016) and member of the Student Papers and Awards Committee (2016–2017). Having almost 25 years of teaching experience, Kroata was one of the most beloved teachers at the Faculty of Phar- macy and Biochemistry, valued and respected by her stu- dents, with whom she nurtured a caring relationship. Most of the students knew her as an excellent professor, full of love and enthusiasm for the plant world, one who enjoyed teach- ing and knew how to spark an interest in those who were not plant lovers in the beginning. In teaching, she tended to be always positive and full of understanding and was very re- spectful to all living beings; plants, animals and people alike. The recognition and appreciation of her work as an educator by students and colleagues were also confirmed through the awards she received: the highest grade for an assistant in the academic year 2005/2006 (according to the university stu- dent survey), and the Award of the Faculty of Pharmacy and Biochemistry, University of Zagreb for exceptional achieve- ments in student education in the academic year 2013/2014. Apart from genuinely enjoying working with students, Kroata had a great curiosity for science as well. However, she tended to be more cautious and realistic in her research. Her colleagues knew her as a hard-working, persistent, respon- sible and conscientious person, who was also unpretentious and modest. She was a patient and encouraging mentor, al- ways ready to help and give useful advice, not just in terms of work and experimental planning, but also in terms of human relations and life in general. I thought of her as a truly warm, motivating, creative and honest person. I am so grateful that, as my PhD mentor, she was open to new ideas and was al- ways ready to encourage my independence in work, while at the same time being very supportive in all my activities, including going to education events, experiencing interna- tional stays, applying for projects or competing for awards. More importantly, she was a loving wife and caring mother of two children, of whose achievements, abilities and sense of responsibility she was very proud. I would also like to mention and appreciate some of the small things that made her happy, like baking cakes, garden- ing, traveling, sailing, ballooning, dancing, enjoying pleasant aromas and finding pleasure in small aesthetic details. We spent a lot of time together, frequently collaborating on a dai- ly basis and occasionally presenting research at congresses or engaging in fieldwork. I had the privilege of learning from her as both her graduate and postgraduate student, through talking and discussing, as well as through sharing new ideas for the future. We were both looking forward to the continu- ation of our co-operation, both in science and in class, and planning new projects for the years to come. Although she passed away so suddenly, with years of her greatest scientific achievements, creations and personal chal- lenges still before her, leaving us all in pain and disbelief, she has undoubtedly left an indelible mark on all who knew her. While her scientific work will certainly be continued, her contributions to the education of thousands of students and to community in general encourage us to be better peo- ple and the best possible in everything we do, until the day we see her again, picking her favourite flowers in the eter- nal fields. Maja Friščić, PhD Department of Pharmaceutical Botany, Faculty of Pharmacy and Biochemistry, University of Zagreb, Schrottova 39, 10 000 Zagreb, Croatia Prof. Kroata Hazler Pilepić (right) and Maja Friščić, PhD (left), dur- ing fieldwork in 2012. The photo was taken by Kroata’s husband, associate professor Viktor Pilepić from the Department of Physical Chemistry, Faculty of Pharmacy and Biochemistry, University of Zagreb. ACTA BOT. CROAT. 77 (1), 2018 S5 List of publications Šugar, I., Brkić, D., Hazler, K., 1994: Medvednica i njezin biljni svijet. Ekološki glasnik 4, 9–10. Vladimir-Knežević, S., Kalođera, Z., Pepeljnjak, S., Blažević, N., Hazler, K., 1994: Activity of essential oil and ethanolic extract isolated from Micromeria thymifolia (Scop.) Fritsch against dermatophytes. Periodicum Biologorum 96, 383–385. Hazler, K., 1997: Genetička struktura bukovih populacija (Fagus sylvatica L.) s područja jugoistočne Europe. Prirodoslovno- matematički fakultet Sveučilišta u Zagrebu, Zagreb, Master’s thesis. Hazler, K., Comps, B., Šugar, I., Melovski, L., Tashev, A., Gračan, J., 1997: Genetic structure of Fagus silvatica L.: populations in Southeastern Europe. Silvae Genetica 46, 229–236. Hazler Pilepić, K., Comps, B., Šugar, I., Šolić, E., 1999: Genetic variability of the Croatian beechwoods. Periodicum Biologo- rum 101, 165–170. Maleš, Ž., Plazibat, M., Hazler Pilepić, K., Cetina Čižmek, B., 2001: Istraživanje aminokiselinskog sastava drače (Paliurus spina- christi Mill.). Farmaceutski glasnik 57, 257–265. Šugar, I., Brkić, D., Ružanović, Z., Partl, A., Hazler Pilepić, K., 2001: Stručna podloga za izradu Pravilnika o korištenju i zaštiti samoniklih farmaceutski i prehrambeno iskoristiv- ih biljnih vrsta. Ministarstvo zaštite okoliša i prostornog uređenja, Expertise. Hazler Pilepić, K., 2002: Analysis of chloroplast DNA variability among some Hypericum species in Croatia. Periodicum Bi- ologorum 104, 457–462. Maleš, Ž., Plazibat, M., Hazler Pilepić, K., Bilušić, V., 2002: Kval- itativna analiza aminokiselina mekolisne majčine dušice – Thymus bracteosus Vis. ex Benth. Farmaceutski glasnik 58, 155–160. Šugar, I., Gostl, I., Hazler Pilepić, K., 2002: Hrvatsko biljno na- zivlje: Analiza hrvatskog biljnog nazivlja u djelu LIBER DE SIMPLICIBUS BENEDICTI RINIJ, Hrvatska sveučilišna na- klada, Zagreb. Hazler Pilepić, K., 2003: Populacijsko-genetička struktura vrste Hypericum perforatum L. (Guttiferae) s područja Hrvatske. Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, Zagreb, PhD thesis. Maleš, Ž., Plazibat, M., Bilušić Vundać, V., Žuntar, I., Hazler Pilepić, K., 2004: Thin-layer chromatographic analysis of fla- vonoids, phenolic acids and amino acids in some Croatian Hypericum taxa. Journal of Planar Chromatography – Mod- ern TLC 17, 280–285. Jurić, S., Lepeduš, H., Hazler-Pilepić, K., Jeličić, B., Fulgosi, H., 2006: TROL integrates chloroplast redox signalling, 46–47. Slovenian Society for Plant Physiology, Ljubljana. Maleš, Ž., Brantner, A., Sović, K., Hazler Pilepić, K., Plazibat, M., 2006: Comparative phytochemical and antimicrobial investi- gations of Hypericum perforatum L. subsp. perforatum and H. perforatum subsp. angustifolium (DC.) Gaudin. Acta Pharma- ceutica 56, 359–367. Fulgosi, H., Hazler Pilepić, K., 2007: Izdvajanje kloroplastne DNA ekstrakcijom fenolom. In: Ambriović Ristov, A., Brozović, A., Bruvo Mađarić, B., Ćetković, H., Herak Bosnar, M., Hranilović, D., Katušić Hećimović, S., Meštrović Radan, N., Mihaljević, S., Slade, N., Vujaklija, D. (eds.), Metode u mole- kularnoj biologiji, 161–163. Institut Ruđer Bošković, Zagreb. Hazler Pilepić, K., 2007: Izdvajanje genomske DNA iz biljnog tki- va. In: Ambriović Ristov, A., Brozović, A., Bruvo Mađarić, B., Ćetković, H., Herak Bosnar, M., Hranilović, D., Katušić Hećimović, S., Meštrović Radan, N., Mihaljević, S., Slade, N., Vujaklija, D. (eds.), Metode u molekularnoj biologiji, 163– 165. Institut Ruđer Bošković, Zagreb. Fulgosi, H., Jurić, S., Lepeduš, H., Hazler-Pilepić, K., Prebeg, T., Ljubešić, N., 2008: Thylakoid system disassembly during bleaching of aurea mutant of maple Acer negundo Hassk. var. Odessanum. Croatica Chemica Acta 81, 89–95. Hazler Pilepić, K., Maleš, Ž., Plazibat, M., 2008: Genetic structure in Hypericum perforatum L. population. Periodicum Biologo- rum 110, 361–365. Maleš, Ž., Babac, M., Hazler Pilepić, K., Zovko, M., 2008: Kvanti- tativna analiza polifenola u nekim vrstama roda Teucrium L. Farmaceutski glasnik 64, 169–177. Jurić, S., Hazler-Pilepić, K., Tomašić, A., Lepeduš, H., Jeličić, B., Puthiyaveetil, S., Bionda, T., Vojta, L., Allen, J. F., Schleiff, E., Fulgosi, H., 2009: Tethering of ferredoxin:NADP+ oxidore- ductase to thylakoid membranes is mediated by novel chlo- roplast protein TROL. Plant Journal 60, 783–794. Maleš, Ž., Hazler Pilepić, K., Bojić, M., Jebrini, S., 2009: Određivanje količine fenolnih spojeva u listovima velike crnjuše – Erica arborea L. Farmaceutski glasnik 65, 217–223. Hazler Pilepić, K., Morović, M., Orač, F., Šantor, M., Vejnović, V., 2010: RFLP analysis of cpDNA in the genus Hypericum. Bio- logia 65, 805–812. Maleš, Ž., Hazler Pilepić, K., Petrović, L., Bagarić, I., 2010: Quan- titative analysis of phenolic compounds of Inula candida (L.) Cass. Periodicum Biologorum 112, 307–310. Maleš, Ž., Hazler Pilepić, K., Šuško, M., 2010: Određivanje količine flavonoida u nekim vrstama roda Hypericum L. Farmaceutski glasnik 66, 653–657. Maleš, Ž., Kremer, D., Gašpar Randić, Z., Randić, M., Hazler Pilepić, K., Bojić, M., 2010: Quantitative analysis of gluco- frangulins and phenolic compounds in Croatian Rhamnus and Frangula species. Acta Biologica Cracoviensia Series Bo- tanica 52, 108–113. Hazler Pilepić, K., 2011: Vježbe iz farmaceutske botanike: his- tologija, anatomija, morfologija i sistematika. Farmaceutsko- biokemijski fakultet Sveučilišta u Zagrebu, Zagreb. Hazler Pilepić, K., Balić, M., Blažina, N., 2011: Estimation of phy- logenetic relationships among some Hypericum (Hypericace- ae) species using ITS sequences. Plant Biosystems 145, 81–87. Hazler Pilepić, K., Božić, I., Lekić, A., Liber, Z., Maleš, Ž., Markić, I., Tabak, M., Žuvela, V., 2012: Low rate of point mutation in the mtDNA noncoding fragment of Hypericum taxa. Periodi- cum Biologorum 114, 33–36. Jerković, I., Gugić, M., Maleš, Ž., Hazler Pilepić, K., 2012: Chem- ical composition of the essential oil from Stachys serotina. Chemistry of Natural Compounds 48, 508–509. Jerković, I., Šuste, M., Maleš, Ž., Hazler Pilepić, K., 2012: Essen- tial oil composition of Prasium majus from Croatia. Natural Product Communications 7, 931–932. Hazler Pilepić, K., Maleš, Ž., 2013: Quantitative analysis of poly- phenols in eighteen Hypericum taxa. Periodicum Biologorum 115, 459–462. Hazler Pilepić, K., Maleš, Ž., Crkvenčić, M., 2013: Quantita- tive analysis of total flavonoids and total phenolic acids in thirty Hypericum taxa. Natural Product Communications 8, 347–349. Jerković, I., Marasović, M., Marijanović, Z., Hazler Pilepić, K., Maleš, Ž., Miloš, M., 2013: Chemical composition of Hyperi- cum richeri subsp. grisebachii essential oil from Croatia. Natu- ral Product Communications 8, 231–233. Jerković, I., Marijanović, Z., Hazler Pilepić, K., Maleš, Ž., 2013: Phytochemical composition of the essential oil of Prunella grandiflora. Chemistry of Natural Compounds 49, 371–373. Maleš, Ž., Crkvenčić, M., Hazler Pilepić, K., Herenda, F., 2013: Istraživanje flavonoida, fenolnih kiselina i aminokiselina gole kilavice – Herniaria glabra L. Farmaceutski glasnik 69, 673–684. https://bib.irb.hr/prikazi-rad?&rad=271779 S6 ACTA BOT. CROAT. 77 (1), 2018 Maleš, Ž., Hazler Pilepić, K., Jakupović, L., Zadravec, D., Marić, S., 2014: Određivanje količine flavonoida i fenolnih kise- lina u pet vrsta roda Teucrium L. Farmaceutski glasnik 70, 231–241. Hazler Pilepić, K., 2015: Vježbe iz farmaceutske botanike. Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, Zagreb. Hazler Pilepić, K., 2015: Kesteni i kesteni. Vaša ljekarna 1, 36–39. Hazler Pilepić, K., 2015: Bijela imela – od mistike do znanstvenih spoznaja. Vaša ljekarna 2, 38–41. Hazler Pilepić, K., Antolković, A., Maleš, Ž., Crkvenčić, M., 2015: Etnobotaničko istraživanje o uporabi biljaka u ljekovite svrhe na području Svetog Ivana Zeline. Farmaceutski glasnik 71, 459–466. Maleš, Ž., Hazler Pilepić, K., Bojić, M., Tatalović, Z., 2015: De- termination of the content of total polyphenols, non-tannin polyphenols and tannins in five species of the genus Teucrium L. Periodicum Biologorum 117, 453–455. Sertić, M., Crkvenčić, M., Mornar, A., Hazler Pilepić, K., Nigović, B., Maleš, Ž., 2015: Analysis of aucubin and catalpol content in different plant parts of four Globularia species. Journal of Applied Botany and Food Quality 88, 209–214. Crkvenčić, M., Dudaš, S., Jerković, I., Marijanović, Z., Poljuha, D., Hazler Pilepić, K., 2016: Essential oil composition of three Globularia species. Chemistry & Biodiversity 13, 219–223. Friščić, M., Bucar, F., Hazler Pilepić, K., 2016: LC-PDA-ESI-MSn analysis of phenolic and iridoid compounds from Globularia spp. Journal of Mass Spectrometry 51, 1211–1236. Hazler Pilepić, K., 2016: Magnolije, ljekovite proljetne ljepotice. Vaša ljekarna 3, 33–35. Hazler Pilepić, K., Čorić, A., Radovčić, M., 2016: Određivanje sadržaja ukupnih hipericina u odabranim vrstama roda Hy- pericum L. Farmaceutski glasnik 72, 377–384. Hazler Pilepić, K., Friščić, M., 2016: Skriveni svijet ljekovitih bil- jaka, izložba. Farmaceutski glasnik 72, 441–443. Hazler Pilepić, K., Friščić, M., Duran, A., Maslo, S., Garić, R., Čuljak, S., Šutalo, K., 2016: Contribution to Globularia phy- logeny based on nuclear ribosomal spacer and two chloroplast DNA regions. Periodicum Biologorum 118, 417–424. Madunić, J., Matulić, M., Friščić, M., Hazler Pilepić, K., 2016: Evaluation of the cytotoxic activity of Hypericum spp. on hu- man glioblastoma A1235 and breast cancer MDA MB-231 cells. Journal of Environmental Science and Health, Part A 51, 1157–1163. Hazler Pilepić, K., Friščić, M., 2017: Skriveni svijet ljekovitih bil- jaka, izložba. Farmaceutski glasnik 73, 465–467. Friščić, M., Maslo, S., Garić, R., Maleš, Ž., Hazler Pilepić, K., 2018: Comparative analysis of specialized metabolites and antioxi- dant capacity in vitro of different natural populations of Glob- ularia spp. Acta Botanica Croatica 77, 1–9.