id	sid	tid	token	lemma	pos
ap-917	1	1	ap08_1.vp	ap08_1.vp	NOUN
ap-917	1	2	abbreviations	abbreviation	NOUN
ap-917	1	3	ncx	ncx	ADP
ap-917	1	4	na	na	PART
ap-917	1	5	�	�	NOUN
ap-917	1	6	/ca2	/ca2	NOUN
ap-917	1	7	�	�	PROPN
ap-917	1	8	exchanger	exchanger	NOUN
ap-917	1	9	sr	sr	PROPN
ap-917	1	10	sarcoplasmic	sarcoplasmic	NOUN
ap-917	1	11	reticulum	reticulum	NOUN
ap-917	1	12	serca	serca	X
ap-917	1	13	sr	sr	PROPN
ap-917	1	14	ca2	ca2	PROPN
ap-917	1	15	�	�	PROPN
ap-917	1	16	influx	influx	PROPN
ap-917	1	17	channel	channel	NOUN
ap-917	1	18	ecc	ecc	PROPN
ap-917	1	19	excitation	excitation	NOUN
ap-917	1	20	-	-	PUNCT
ap-917	1	21	contraction	contraction	NOUN
ap-917	1	22	coupling	couple	VERB
ap-917	1	23	nf	nf	ADP
ap-917	1	24	non	non	ADJ
ap-917	1	25	-	-	ADJ
ap-917	1	26	failing	failing	ADJ
ap-917	1	27	heart	heart	NOUN
ap-917	1	28	f	f	PROPN
ap-917	1	29	failing	fail	VERB
ap-917	1	30	heart	heart	NOUN
ap-917	1	31	am	be	AUX
ap-917	1	32	actomyosin	actomyosin	NOUN
ap-917	1	33	complex	complex	ADJ
ap-917	1	34	1	1	NUM
ap-917	1	35	introduction	introduction	NOUN
ap-917	1	36	the	the	DET
ap-917	1	37	number	number	NOUN
ap-917	1	38	of	of	ADP
ap-917	1	39	known	know	VERB
ap-917	1	40	molecular	molecular	NOUN
ap-917	1	41	of	of	ADP
ap-917	1	42	cardiac	cardiac	ADJ
ap-917	1	43	excitation	excitation	NOUN
ap-917	1	44	-	-	PUNCT
ap-917	1	45	contraction	contraction	NOUN
ap-917	1	46	coupling	coupling	NOUN
ap-917	1	47	(	(	PUNCT
ap-917	1	48	ecc	ecc	NOUN
ap-917	1	49	)	)	PUNCT
ap-917	1	50	mechanisms	mechanism	NOUN
ap-917	1	51	is	be	AUX
ap-917	1	52	enormous	enormous	ADJ
ap-917	1	53	and	and	CCONJ
ap-917	1	54	is	be	AUX
ap-917	1	55	still	still	ADV
ap-917	1	56	growing	grow	VERB
ap-917	1	57	.	.	PUNCT
ap-917	2	1	it	it	PRON
ap-917	2	2	has	have	AUX
ap-917	2	3	become	become	VERB
ap-917	2	4	impossible	impossible	ADJ
ap-917	2	5	to	to	PART
ap-917	2	6	intuitively	intuitively	ADV
ap-917	2	7	assess	assess	VERB
ap-917	2	8	the	the	DET
ap-917	2	9	relative	relative	ADJ
ap-917	2	10	contribution	contribution	NOUN
ap-917	2	11	of	of	ADP
ap-917	2	12	an	an	DET
ap-917	2	13	individual	individual	ADJ
ap-917	2	14	arrangement	arrangement	NOUN
ap-917	2	15	in	in	ADP
ap-917	2	16	physiological	physiological	ADJ
ap-917	2	17	and	and	CCONJ
ap-917	2	18	pathophysiological	pathophysiological	ADJ
ap-917	2	19	events	event	NOUN
ap-917	2	20	.	.	PUNCT
ap-917	3	1	however	however	ADV
ap-917	3	2	,	,	PUNCT
ap-917	3	3	such	such	ADJ
ap-917	3	4	understanding	understanding	NOUN
ap-917	3	5	is	be	AUX
ap-917	3	6	essential	essential	ADJ
ap-917	3	7	for	for	ADP
ap-917	3	8	identifying	identify	VERB
ap-917	3	9	strategies	strategy	NOUN
ap-917	3	10	for	for	ADP
ap-917	3	11	treating	treat	VERB
ap-917	3	12	various	various	ADJ
ap-917	3	13	types	type	NOUN
ap-917	3	14	of	of	ADP
ap-917	3	15	heart	heart	NOUN
ap-917	3	16	failure	failure	NOUN
ap-917	3	17	.	.	PUNCT
ap-917	4	1	mathematical	mathematical	ADJ
ap-917	4	2	modeling	modeling	NOUN
ap-917	4	3	and	and	CCONJ
ap-917	4	4	simulation	simulation	NOUN
ap-917	4	5	offers	offer	VERB
ap-917	4	6	a	a	DET
ap-917	4	7	way	way	NOUN
ap-917	4	8	of	of	ADP
ap-917	4	9	handling	handle	VERB
ap-917	4	10	such	such	DET
ap-917	4	11	an	an	DET
ap-917	4	12	extensive	extensive	ADJ
ap-917	4	13	set	set	NOUN
ap-917	4	14	of	of	ADP
ap-917	4	15	data	datum	NOUN
ap-917	4	16	,	,	PUNCT
ap-917	4	17	while	while	SCONJ
ap-917	4	18	still	still	ADV
ap-917	4	19	allowing	allow	VERB
ap-917	4	20	for	for	ADP
ap-917	4	21	a	a	DET
ap-917	4	22	(	(	PUNCT
ap-917	4	23	semi)quantitative	semi)quantitative	ADJ
ap-917	4	24	study	study	NOUN
ap-917	4	25	.	.	PUNCT
ap-917	5	1	of	of	ADP
ap-917	5	2	course	course	NOUN
ap-917	5	3	,	,	PUNCT
ap-917	5	4	there	there	PRON
ap-917	5	5	are	be	VERB
ap-917	5	6	limitations	limitation	NOUN
ap-917	5	7	to	to	ADP
ap-917	5	8	such	such	DET
ap-917	5	9	an	an	DET
ap-917	5	10	approach	approach	NOUN
ap-917	5	11	,	,	PUNCT
ap-917	5	12	mainly	mainly	ADV
ap-917	5	13	:	:	PUNCT
ap-917	5	14	the	the	DET
ap-917	5	15	accuracy	accuracy	NOUN
ap-917	5	16	of	of	ADP
ap-917	5	17	the	the	DET
ap-917	5	18	model	model	NOUN
ap-917	5	19	,	,	PUNCT
ap-917	5	20	its	its	PRON
ap-917	5	21	complexity	complexity	NOUN
ap-917	5	22	(	(	PUNCT
ap-917	5	23	always	always	ADV
ap-917	5	24	drastically	drastically	ADV
ap-917	5	25	lower	low	ADJ
ap-917	5	26	than	than	ADP
ap-917	5	27	in	in	ADP
ap-917	5	28	reality	reality	NOUN
ap-917	5	29	)	)	PUNCT
ap-917	5	30	,	,	PUNCT
ap-917	5	31	low	low	ADJ
ap-917	5	32	availability	availability	NOUN
ap-917	5	33	of	of	ADP
ap-917	5	34	consistent	consistent	ADJ
ap-917	5	35	experimental	experimental	ADJ
ap-917	5	36	input	input	NOUN
ap-917	5	37	data	datum	NOUN
ap-917	5	38	,	,	PUNCT
ap-917	5	39	etc	etc	X
ap-917	5	40	.	.	X
ap-917	5	41	however	however	ADV
ap-917	5	42	,	,	PUNCT
ap-917	5	43	calculations	calculation	NOUN
ap-917	5	44	and	and	CCONJ
ap-917	5	45	simulations	simulation	NOUN
ap-917	5	46	have	have	AUX
ap-917	5	47	been	be	AUX
ap-917	5	48	already	already	ADV
ap-917	5	49	proven	prove	VERB
ap-917	5	50	to	to	PART
ap-917	5	51	be	be	AUX
ap-917	5	52	useful	useful	ADJ
ap-917	5	53	in	in	ADP
ap-917	5	54	biological	biological	ADJ
ap-917	5	55	research	research	NOUN
ap-917	5	56	.	.	PUNCT
ap-917	6	1	as	as	ADP
ap-917	6	2	an	an	DET
ap-917	6	3	example	example	NOUN
ap-917	6	4	,	,	PUNCT
ap-917	6	5	let	let	VERB
ap-917	6	6	us	we	PRON
ap-917	6	7	mention	mention	VERB
ap-917	6	8	the	the	DET
ap-917	6	9	correct	correct	NOUN
ap-917	6	10	of	of	ADP
ap-917	6	11	na	na	NOUN
ap-917	6	12	-	-	ADJ
ap-917	6	13	k	k	PROPN
ap-917	6	14	exchanger	exchanger	NOUN
ap-917	6	15	stoichiometry	stoichiometry	NOUN
ap-917	6	16	3:1	3:1	NUM
ap-917	6	17	,	,	PUNCT
ap-917	6	18	based	base	VERB
ap-917	6	19	on	on	ADP
ap-917	6	20	simulations	simulation	NOUN
ap-917	6	21	prediction	prediction	NOUN
ap-917	6	22	as	as	ADV
ap-917	6	23	early	early	ADV
ap-917	6	24	as	as	ADP
ap-917	6	25	1985	1985	NUM
ap-917	6	26	.	.	PUNCT
ap-917	7	1	[	[	X
ap-917	7	2	1	1	X
ap-917	7	3	]	]	PUNCT
ap-917	7	4	the	the	DET
ap-917	7	5	aim	aim	NOUN
ap-917	7	6	of	of	ADP
ap-917	7	7	the	the	DET
ap-917	7	8	present	present	ADJ
ap-917	7	9	study	study	NOUN
ap-917	7	10	is	be	AUX
ap-917	7	11	to	to	PART
ap-917	7	12	assess	assess	VERB
ap-917	7	13	the	the	DET
ap-917	7	14	relative	relative	ADJ
ap-917	7	15	contribution	contribution	NOUN
ap-917	7	16	of	of	ADP
ap-917	7	17	ncx	ncx	NOUN
ap-917	7	18	and	and	CCONJ
ap-917	7	19	serca	serca	NOUN
ap-917	7	20	to	to	ADP
ap-917	7	21	the	the	DET
ap-917	7	22	function	function	NOUN
ap-917	7	23	of	of	ADP
ap-917	7	24	cardiac	cardiac	ADJ
ap-917	7	25	myocytes	myocyte	NOUN
ap-917	7	26	and	and	CCONJ
ap-917	7	27	thus	thus	ADV
ap-917	7	28	to	to	PART
ap-917	7	29	help	help	VERB
ap-917	7	30	interpret	interpret	VERB
ap-917	7	31	experimental	experimental	ADJ
ap-917	7	32	data	datum	NOUN
ap-917	7	33	.	.	PUNCT
ap-917	8	1	generally	generally	ADV
ap-917	8	2	,	,	PUNCT
ap-917	8	3	both	both	DET
ap-917	8	4	proteins	protein	NOUN
ap-917	8	5	reduce	reduce	VERB
ap-917	8	6	the	the	DET
ap-917	8	7	cytoplasmic	cytoplasmic	ADJ
ap-917	8	8	concentration	concentration	NOUN
ap-917	8	9	of	of	ADP
ap-917	8	10	ca2	ca2	PROPN
ap-917	8	11	�	�	PROPN
ap-917	8	12	,	,	PUNCT
ap-917	8	13	and	and	CCONJ
ap-917	8	14	influence	influence	NOUN
ap-917	8	15	both	both	CCONJ
ap-917	8	16	the	the	DET
ap-917	8	17	systolic	systolic	ADJ
ap-917	8	18	(	(	PUNCT
ap-917	8	19	contraction	contraction	NOUN
ap-917	8	20	)	)	PUNCT
ap-917	8	21	and	and	CCONJ
ap-917	8	22	the	the	DET
ap-917	8	23	diastolic	diastolic	NOUN
ap-917	8	24	(	(	PUNCT
ap-917	8	25	relaxation	relaxation	NOUN
ap-917	8	26	)	)	PUNCT
ap-917	8	27	function	function	NOUN
ap-917	8	28	.	.	PUNCT
ap-917	9	1	while	while	SCONJ
ap-917	9	2	serca	serca	PROPN
ap-917	9	3	transports	transport	VERB
ap-917	9	4	ca2	ca2	PROPN
ap-917	9	5	�	�	PROPN
ap-917	9	6	into	into	ADP
ap-917	9	7	the	the	DET
ap-917	9	8	sarcoplasmic	sarcoplasmic	NOUN
ap-917	9	9	reticulum	reticulum	NOUN
ap-917	9	10	(	(	PUNCT
ap-917	9	11	sr	sr	PROPN
ap-917	9	12	)	)	PUNCT
ap-917	9	13	and	and	CCONJ
ap-917	9	14	so	so	ADV
ap-917	9	15	increases	increase	VERB
ap-917	9	16	intracellular	intracellular	ADJ
ap-917	9	17	calcium	calcium	NOUN
ap-917	9	18	stores	store	NOUN
ap-917	9	19	,	,	PUNCT
ap-917	9	20	i.e.	i.e.	X
ap-917	9	21	the	the	DET
ap-917	9	22	systolic	systolic	ADJ
ap-917	9	23	function	function	NOUN
ap-917	9	24	,	,	PUNCT
ap-917	9	25	ncx	ncx	ADP
ap-917	9	26	removes	remove	VERB
ap-917	9	27	ca2	ca2	PROPN
ap-917	9	28	�	�	PROPN
ap-917	9	29	across	across	ADP
ap-917	9	30	the	the	DET
ap-917	9	31	cellular	cellular	ADJ
ap-917	9	32	membrane	membrane	NOUN
ap-917	9	33	out	out	ADP
ap-917	9	34	of	of	ADP
ap-917	9	35	the	the	DET
ap-917	9	36	cell	cell	NOUN
ap-917	9	37	(	(	PUNCT
ap-917	9	38	fig	fig	NOUN
ap-917	9	39	.	.	NOUN
ap-917	9	40	1	1	NUM
ap-917	9	41	)	)	PUNCT
ap-917	9	42	,	,	PUNCT
ap-917	9	43	so	so	SCONJ
ap-917	9	44	that	that	SCONJ
ap-917	9	45	the	the	DET
ap-917	9	46	total	total	ADJ
ap-917	9	47	cellular	cellular	ADJ
ap-917	9	48	calcium	calcium	NOUN
ap-917	9	49	is	be	AUX
ap-917	9	50	reduced	reduce	VERB
ap-917	9	51	and	and	CCONJ
ap-917	9	52	thus	thus	ADV
ap-917	9	53	the	the	DET
ap-917	9	54	systolic	systolic	ADJ
ap-917	9	55	function	function	NOUN
ap-917	9	56	is	be	AUX
ap-917	9	57	decreased	decrease	VERB
ap-917	9	58	.	.	PUNCT
ap-917	10	1	the	the	DET
ap-917	10	2	role	role	NOUN
ap-917	10	3	of	of	ADP
ap-917	10	4	ncx	ncx	NOUN
ap-917	10	5	is	be	AUX
ap-917	10	6	far	far	ADV
ap-917	10	7	more	more	ADV
ap-917	10	8	complex	complex	ADJ
ap-917	10	9	,	,	PUNCT
ap-917	10	10	since	since	SCONJ
ap-917	10	11	it	it	PRON
ap-917	10	12	is	be	AUX
ap-917	10	13	regulated	regulate	VERB
ap-917	10	14	by	by	ADP
ap-917	10	15	voltage	voltage	NOUN
ap-917	10	16	and	and	CCONJ
ap-917	10	17	by	by	ADP
ap-917	10	18	ca2	ca2	PROPN
ap-917	10	19	�	�	PROPN
ap-917	10	20	and	and	CCONJ
ap-917	10	21	na	na	ADP
ap-917	10	22	�	�	PROPN
ap-917	10	23	concentration	concentration	NOUN
ap-917	10	24	.	.	PUNCT
ap-917	11	1	consequently	consequently	ADV
ap-917	11	2	,	,	PUNCT
ap-917	11	3	it	it	PRON
ap-917	11	4	can	can	AUX
ap-917	11	5	operate	operate	VERB
ap-917	11	6	in	in	ADP
ap-917	11	7	so	so	ADV
ap-917	11	8	-	-	PUNCT
ap-917	11	9	called	call	VERB
ap-917	11	10	“	"	PUNCT
ap-917	11	11	reverse	reverse	ADJ
ap-917	11	12	mode	mode	NOUN
ap-917	11	13	”	"	PUNCT
ap-917	11	14	during	during	ADP
ap-917	11	15	the	the	DET
ap-917	11	16	early	early	ADJ
ap-917	11	17	phase	phase	NOUN
ap-917	11	18	of	of	ADP
ap-917	11	19	action	action	NOUN
ap-917	11	20	potential	potential	NOUN
ap-917	11	21	.	.	PUNCT
ap-917	12	1	heart	heart	NOUN
ap-917	12	2	failure	failure	NOUN
ap-917	12	3	congestive	congestive	NOUN
ap-917	12	4	heart	heart	NOUN
ap-917	12	5	failure	failure	NOUN
ap-917	12	6	is	be	AUX
ap-917	12	7	an	an	DET
ap-917	12	8	important	important	ADJ
ap-917	12	9	medical	medical	ADJ
ap-917	12	10	issue	issue	NOUN
ap-917	12	11	with	with	ADP
ap-917	12	12	very	very	ADV
ap-917	12	13	high	high	ADJ
ap-917	12	14	mortality	mortality	NOUN
ap-917	12	15	and	and	CCONJ
ap-917	12	16	no	no	DET
ap-917	12	17	targeted	targeted	ADJ
ap-917	12	18	treatment	treatment	NOUN
ap-917	12	19	available	available	ADJ
ap-917	12	20	.	.	PUNCT
ap-917	13	1	though	though	SCONJ
ap-917	13	2	it	it	PRON
ap-917	13	3	is	be	AUX
ap-917	13	4	among	among	ADP
ap-917	13	5	the	the	DET
ap-917	13	6	leading	lead	VERB
ap-917	13	7	causes	cause	NOUN
ap-917	13	8	of	of	ADP
ap-917	13	9	death	death	NOUN
ap-917	13	10	in	in	ADP
ap-917	13	11	our	our	PRON
ap-917	13	12	population	population	NOUN
ap-917	13	13	,	,	PUNCT
ap-917	13	14	the	the	DET
ap-917	13	15	underlying	underlying	ADJ
ap-917	13	16	pathophysiological	pathophysiological	ADJ
ap-917	13	17	mechanisms	mechanism	NOUN
ap-917	13	18	at	at	ADP
ap-917	13	19	molecular	molecular	ADJ
ap-917	13	20	level	level	NOUN
ap-917	13	21	remain	remain	VERB
ap-917	13	22	to	to	PART
ap-917	13	23	be	be	AUX
ap-917	13	24	elucidated	elucidate	VERB
ap-917	13	25	.	.	PUNCT
ap-917	14	1	altered	alter	VERB
ap-917	14	2	calcium	calcium	NOUN
ap-917	14	3	(	(	PUNCT
ap-917	14	4	ca2	ca2	PROPN
ap-917	14	5	�	�	PROPN
ap-917	14	6	)	)	PUNCT
ap-917	14	7	handling	handling	NOUN
ap-917	14	8	is	be	AUX
ap-917	14	9	seen	see	VERB
ap-917	14	10	as	as	ADP
ap-917	14	11	a	a	DET
ap-917	14	12	key	key	ADJ
ap-917	14	13	factor	factor	NOUN
ap-917	14	14	in	in	ADP
ap-917	14	15	the	the	DET
ap-917	14	16	pathophysiology	pathophysiology	NOUN
ap-917	14	17	of	of	ADP
ap-917	14	18	heart	heart	NOUN
ap-917	14	19	failure	failure	NOUN
ap-917	14	20	.	.	PUNCT
ap-917	15	1	typically	typically	ADV
ap-917	15	2	,	,	PUNCT
ap-917	15	3	serca	serca	NOUN
ap-917	15	4	activity	activity	NOUN
ap-917	15	5	is	be	AUX
ap-917	15	6	consistently	consistently	ADV
ap-917	15	7	reported	report	VERB
ap-917	15	8	to	to	PART
ap-917	15	9	be	be	AUX
ap-917	15	10	reduced	reduce	VERB
ap-917	15	11	in	in	ADP
ap-917	15	12	cases	case	NOUN
ap-917	15	13	of	of	ADP
ap-917	15	14	advanced	advanced	ADJ
ap-917	15	15	cardiac	cardiac	ADJ
ap-917	15	16	dysfunction	dysfunction	NOUN
ap-917	16	1	[	[	X
ap-917	16	2	2	2	NUM
ap-917	16	3	,	,	PUNCT
ap-917	16	4	3	3	NUM
ap-917	16	5	]	]	PUNCT
ap-917	16	6	.	.	PUNCT
ap-917	17	1	the	the	DET
ap-917	17	2	na	na	PART
ap-917	17	3	�	�	PROPN
ap-917	17	4	/ca2	/ca2	NOUN
ap-917	17	5	�	�	PROPN
ap-917	17	6	exchanger	exchanger	NOUN
ap-917	17	7	(	(	PUNCT
ap-917	17	8	ncx	ncx	NOUN
ap-917	17	9	)	)	PUNCT
ap-917	17	10	has	have	AUX
ap-917	17	11	also	also	ADV
ap-917	17	12	been	be	AUX
ap-917	17	13	reported	report	VERB
ap-917	17	14	to	to	PART
ap-917	17	15	be	be	AUX
ap-917	17	16	altered	alter	VERB
ap-917	17	17	in	in	ADP
ap-917	17	18	heart	heart	NOUN
ap-917	17	19	failure	failure	NOUN
ap-917	17	20	and	and	CCONJ
ap-917	17	21	the	the	DET
ap-917	17	22	currently	currently	ADV
ap-917	17	23	attracting	attract	VERB
ap-917	17	24	strong	strong	ADJ
ap-917	17	25	interest	interest	NOUN
ap-917	18	1	[	[	X
ap-917	18	2	4	4	NUM
ap-917	18	3	]	]	PUNCT
ap-917	18	4	.	.	PUNCT
ap-917	19	1	the	the	DET
ap-917	19	2	transporter	transporter	NOUN
ap-917	19	3	may	may	AUX
ap-917	19	4	be	be	AUX
ap-917	19	5	over	over	ADV
ap-917	19	6	-	-	PUNCT
ap-917	19	7	expressed	express	VERB
ap-917	19	8	[	[	X
ap-917	19	9	5	5	NUM
ap-917	19	10	]	]	PUNCT
ap-917	19	11	or	or	CCONJ
ap-917	19	12	normal	normal	ADJ
ap-917	19	13	or	or	CCONJ
ap-917	19	14	even	even	ADV
ap-917	19	15	reduced	reduce	VERB
ap-917	19	16	.	.	PUNCT
ap-917	20	1	the	the	DET
ap-917	20	2	ratio	ratio	NOUN
ap-917	20	3	between	between	ADP
ap-917	20	4	the	the	DET
ap-917	20	5	two	two	NUM
ap-917	20	6	mechanisms	mechanism	NOUN
ap-917	20	7	seems	seem	VERB
ap-917	20	8	to	to	PART
ap-917	20	9	be	be	AUX
ap-917	20	10	an	an	DET
ap-917	20	11	important	important	ADJ
ap-917	20	12	determinant	determinant	NOUN
ap-917	20	13	of	of	ADP
ap-917	20	14	overall	overall	ADJ
ap-917	20	15	function	function	NOUN
ap-917	20	16	[	[	X
ap-917	20	17	2	2	NUM
ap-917	20	18	]	]	PUNCT
ap-917	20	19	.	.	PUNCT
ap-917	21	1	the	the	DET
ap-917	21	2	model	model	NOUN
ap-917	21	3	used	use	VERB
ap-917	21	4	for	for	ADP
ap-917	21	5	the	the	DET
ap-917	21	6	present	present	ADJ
ap-917	21	7	work	work	NOUN
ap-917	21	8	is	be	AUX
ap-917	21	9	far	far	ADV
ap-917	21	10	from	from	ADP
ap-917	21	11	reproducing	reproduce	VERB
ap-917	21	12	all	all	DET
ap-917	21	13	known	know	VERB
ap-917	21	14	mechanisms	mechanism	NOUN
ap-917	21	15	of	of	ADP
ap-917	21	16	ecc	ecc	PROPN
ap-917	21	17	.	.	PUNCT
ap-917	22	1	however	however	ADV
ap-917	22	2	,	,	PUNCT
ap-917	22	3	it	it	PRON
ap-917	22	4	can	can	AUX
ap-917	22	5	still	still	ADV
ap-917	22	6	provide	provide	VERB
ap-917	22	7	a	a	DET
ap-917	22	8	valuable	valuable	ADJ
ap-917	22	9	quantitative	quantitative	NOUN
ap-917	22	10	(	(	PUNCT
ap-917	22	11	or	or	CCONJ
ap-917	22	12	semi	semi	ADJ
ap-917	22	13	-	-	ADJ
ap-917	22	14	quantitative	quantitative	ADJ
ap-917	22	15	)	)	PUNCT
ap-917	22	16	insight	insight	NOUN
ap-917	22	17	by	by	ADP
ap-917	22	18	providing	provide	VERB
ap-917	22	19	calculated	calculated	ADJ
ap-917	22	20	data	datum	NOUN
ap-917	22	21	that	that	PRON
ap-917	22	22	can	can	AUX
ap-917	22	23	help	help	VERB
ap-917	22	24	to	to	PART
ap-917	22	25	decide	decide	VERB
ap-917	22	26	which	which	PRON
ap-917	22	27	are	be	AUX
ap-917	22	28	the	the	DET
ap-917	22	29	direct	direct	ADJ
ap-917	22	30	effects	effect	NOUN
ap-917	22	31	of	of	ADP
ap-917	22	32	ncx	ncx	NOUN
ap-917	22	33	on	on	ADP
ap-917	22	34	cellular	cellular	ADJ
ap-917	22	35	performance	performance	NOUN
ap-917	22	36	(	(	PUNCT
ap-917	22	37	under	under	ADP
ap-917	22	38	our	our	PRON
ap-917	22	39	©	©	PROPN
ap-917	22	40	czech	czech	PROPN
ap-917	22	41	technical	technical	PROPN
ap-917	22	42	university	university	PROPN
ap-917	22	43	publishing	publishing	NOUN
ap-917	22	44	house	house	NOUN
ap-917	22	45	http://ctn.cvut.cz/ap/	http://ctn.cvut.cz/ap/	PROPN
ap-917	22	46	3	3	NUM
ap-917	22	47	acta	acta	PROPN
ap-917	22	48	polytechnica	polytechnica	PROPN
ap-917	22	49	vol	vol	NOUN
ap-917	22	50	.	.	PUNCT
ap-917	23	1	48	48	NUM
ap-917	23	2	no	no	NOUN
ap-917	23	3	.	.	PUNCT
ap-917	24	1	1/2008	1/2008	NUM
ap-917	24	2	computer	computer	NOUN
ap-917	24	3	insight	insight	NOUN
ap-917	24	4	into	into	ADP
ap-917	24	5	the	the	DET
ap-917	24	6	molecular	molecular	ADJ
ap-917	24	7	level	level	NOUN
ap-917	24	8	of	of	ADP
ap-917	24	9	heart	heart	NOUN
ap-917	24	10	failure	failure	NOUN
ap-917	24	11	.	.	PUNCT
ap-917	25	1	what	what	PRON
ap-917	25	2	is	be	AUX
ap-917	25	3	the	the	DET
ap-917	25	4	role	role	NOUN
ap-917	25	5	of	of	ADP
ap-917	25	6	ncx	ncx	PROPN
ap-917	25	7	?	?	PUNCT
ap-917	25	8	m.	m.	NOUN
ap-917	25	9	fischer	fischer	PROPN
ap-917	25	10	,	,	PUNCT
ap-917	25	11	m.	m.	NOUN
ap-917	25	12	mlček	mlček	PROPN
ap-917	25	13	,	,	PUNCT
ap-917	25	14	s.	s.	PROPN
ap-917	25	15	konvičková	konvičková	PROPN
ap-917	25	16	,	,	PUNCT
ap-917	25	17	o.	o.	PROPN
ap-917	25	18	kittnar	kittnar	PROPN
ap-917	25	19	though	though	SCONJ
ap-917	25	20	congestive	congestive	ADJ
ap-917	25	21	heart	heart	NOUN
ap-917	25	22	failure	failure	NOUN
ap-917	25	23	is	be	AUX
ap-917	25	24	a	a	DET
ap-917	25	25	leading	lead	VERB
ap-917	25	26	cause	cause	NOUN
ap-917	25	27	of	of	ADP
ap-917	25	28	death	death	NOUN
ap-917	25	29	in	in	ADP
ap-917	25	30	our	our	PRON
ap-917	25	31	population	population	NOUN
ap-917	25	32	,	,	PUNCT
ap-917	25	33	the	the	DET
ap-917	25	34	pathophysiological	pathophysiological	ADJ
ap-917	25	35	mechanisms	mechanism	NOUN
ap-917	25	36	at	at	ADP
ap-917	25	37	molecular	molecular	ADJ
ap-917	25	38	level	level	NOUN
ap-917	25	39	remain	remain	VERB
ap-917	25	40	to	to	PART
ap-917	25	41	be	be	AUX
ap-917	25	42	elucidated	elucidate	VERB
ap-917	25	43	.	.	PUNCT
ap-917	26	1	this	this	DET
ap-917	26	2	paper	paper	NOUN
ap-917	26	3	discusses	discuss	VERB
ap-917	26	4	the	the	DET
ap-917	26	5	contribution	contribution	NOUN
ap-917	26	6	of	of	ADP
ap-917	26	7	ncx	ncx	NOUN
ap-917	26	8	to	to	ADP
ap-917	26	9	the	the	DET
ap-917	26	10	pathological	pathological	ADJ
ap-917	26	11	pattern	pattern	NOUN
ap-917	26	12	of	of	ADP
ap-917	26	13	intracellular	intracellular	ADJ
ap-917	26	14	calcium	calcium	NOUN
ap-917	26	15	regulation	regulation	NOUN
ap-917	26	16	and	and	CCONJ
ap-917	26	17	contraction	contraction	NOUN
ap-917	26	18	on	on	ADP
ap-917	26	19	the	the	DET
ap-917	26	20	basis	basis	NOUN
ap-917	26	21	of	of	ADP
ap-917	26	22	computer	computer	NOUN
ap-917	26	23	simulations	simulation	NOUN
ap-917	26	24	of	of	ADP
ap-917	26	25	a	a	DET
ap-917	26	26	virtual	virtual	ADJ
ap-917	26	27	cell	cell	NOUN
ap-917	26	28	.	.	PUNCT
ap-917	27	1	the	the	DET
ap-917	27	2	model	model	NOUN
ap-917	27	3	comprises	comprise	VERB
ap-917	27	4	calcium	calcium	NOUN
ap-917	27	5	handling	handling	NOUN
ap-917	27	6	mechanisms	mechanism	NOUN
ap-917	27	7	,	,	PUNCT
ap-917	27	8	troponin	troponin	ADJ
ap-917	27	9	control	control	NOUN
ap-917	27	10	and	and	CCONJ
ap-917	27	11	acto	acto	PROPN
ap-917	27	12	-	-	PUNCT
ap-917	27	13	myosin	myosin	NOUN
ap-917	27	14	interactions	interaction	NOUN
ap-917	27	15	.	.	PUNCT
ap-917	28	1	the	the	DET
ap-917	28	2	contribution	contribution	NOUN
ap-917	28	3	of	of	ADP
ap-917	28	4	ncx	ncx	NOUN
ap-917	28	5	was	be	AUX
ap-917	28	6	studied	study	VERB
ap-917	28	7	by	by	ADP
ap-917	28	8	changing	change	VERB
ap-917	28	9	its	its	PRON
ap-917	28	10	activity	activity	NOUN
ap-917	28	11	and	and	CCONJ
ap-917	28	12	turning	turn	VERB
ap-917	28	13	it	it	PRON
ap-917	28	14	off	off	ADP
ap-917	28	15	for	for	ADP
ap-917	28	16	some	some	DET
ap-917	28	17	simulations	simulation	NOUN
ap-917	28	18	.	.	PUNCT
ap-917	29	1	it	it	PRON
ap-917	29	2	was	be	AUX
ap-917	29	3	found	find	VERB
ap-917	29	4	that	that	SCONJ
ap-917	29	5	ncx	ncx	NOUN
ap-917	29	6	helps	help	VERB
ap-917	29	7	to	to	PART
ap-917	29	8	support	support	VERB
ap-917	29	9	diastolic	diastolic	ADJ
ap-917	29	10	function	function	NOUN
ap-917	29	11	by	by	ADP
ap-917	29	12	reducing	reduce	VERB
ap-917	29	13	the	the	DET
ap-917	29	14	ca2	ca2	PROPN
ap-917	29	15	�	�	PROPN
ap-917	29	16	level	level	NOUN
ap-917	29	17	during	during	ADP
ap-917	29	18	the	the	DET
ap-917	29	19	diastole	diastole	NOUN
ap-917	29	20	.	.	PUNCT
ap-917	30	1	at	at	ADP
ap-917	30	2	the	the	DET
ap-917	30	3	same	same	ADJ
ap-917	30	4	time	time	NOUN
ap-917	30	5	there	there	PRON
ap-917	30	6	is	be	VERB
ap-917	30	7	a	a	DET
ap-917	30	8	reduction	reduction	NOUN
ap-917	30	9	in	in	ADP
ap-917	30	10	peak	peak	NOUN
ap-917	30	11	cai	cai	NOUN
ap-917	30	12	and	and	CCONJ
ap-917	30	13	hence	hence	ADV
ap-917	30	14	contraction	contraction	NOUN
ap-917	30	15	.	.	PUNCT
ap-917	31	1	however	however	ADV
ap-917	31	2	,	,	PUNCT
ap-917	31	3	increased	increase	VERB
ap-917	31	4	ncx	ncx	ADP
ap-917	31	5	activity	activity	NOUN
ap-917	31	6	does	do	AUX
ap-917	31	7	not	not	PART
ap-917	31	8	seem	seem	VERB
ap-917	31	9	to	to	PART
ap-917	31	10	improve	improve	VERB
ap-917	31	11	calcium	calcium	NOUN
ap-917	31	12	handling	handling	NOUN
ap-917	31	13	and	and	CCONJ
ap-917	31	14	contraction	contraction	NOUN
ap-917	31	15	crucially	crucially	ADV
ap-917	31	16	,	,	PUNCT
ap-917	31	17	as	as	SCONJ
ap-917	31	18	has	have	AUX
ap-917	31	19	been	be	AUX
ap-917	31	20	suggested	suggest	VERB
ap-917	31	21	by	by	ADP
ap-917	31	22	some	some	DET
ap-917	31	23	authors	author	NOUN
ap-917	31	24	.	.	PUNCT
ap-917	32	1	keywords	keyword	NOUN
ap-917	32	2	:	:	PUNCT
ap-917	32	3	heart	heart	NOUN
ap-917	32	4	failure	failure	NOUN
ap-917	32	5	,	,	PUNCT
ap-917	32	6	numerical	numerical	ADJ
ap-917	32	7	models	model	NOUN
ap-917	32	8	,	,	PUNCT
ap-917	32	9	calcium	calcium	NOUN
ap-917	32	10	,	,	PUNCT
ap-917	32	11	ncx	ncx	PROPN
ap-917	32	12	.	.	PUNCT
ap-917	32	13	fig	fig	NOUN
ap-917	32	14	.	.	PUNCT
ap-917	33	1	1	1	NUM
ap-917	33	2	:	:	PUNCT
ap-917	33	3	some	some	DET
ap-917	33	4	ca2	ca2	PROPN
ap-917	33	5	�	�	PROPN
ap-917	33	6	transport	transport	NOUN
ap-917	33	7	mechanisms	mechanism	NOUN
ap-917	33	8	in	in	ADP
ap-917	33	9	heart	heart	NOUN
ap-917	33	10	cell	cell	NOUN
ap-917	33	11	limited	limit	VERB
ap-917	33	12	conditions	condition	NOUN
ap-917	33	13	)	)	PUNCT
ap-917	33	14	,	,	PUNCT
ap-917	33	15	and	and	CCONJ
ap-917	33	16	which	which	DET
ap-917	33	17	findings	finding	NOUN
ap-917	33	18	can	can	AUX
ap-917	33	19	not	not	PART
ap-917	33	20	be	be	AUX
ap-917	33	21	attributed	attribute	VERB
ap-917	33	22	to	to	ADP
ap-917	33	23	ncx	ncx	VERB
ap-917	33	24	and	and	CCONJ
ap-917	33	25	require	require	VERB
ap-917	33	26	identification	identification	NOUN
ap-917	33	27	and/or	and/or	CCONJ
ap-917	33	28	the	the	DET
ap-917	33	29	addition	addition	NOUN
ap-917	33	30	of	of	ADP
ap-917	33	31	other	other	ADJ
ap-917	33	32	mechanisms	mechanism	NOUN
ap-917	33	33	.	.	PUNCT
ap-917	34	1	2	2	NUM
ap-917	34	2	materials	material	NOUN
ap-917	34	3	and	and	CCONJ
ap-917	34	4	methods	method	NOUN
ap-917	34	5	2.1	2.1	NUM
ap-917	34	6	model	model	NOUN
ap-917	34	7	an	an	DET
ap-917	34	8	extended	extended	ADJ
ap-917	34	9	version	version	NOUN
ap-917	34	10	of	of	ADP
ap-917	34	11	our	our	PRON
ap-917	34	12	earlier	early	ADJ
ap-917	34	13	excitation	excitation	NOUN
ap-917	34	14	-	-	PUNCT
ap-917	34	15	contraction	contraction	NOUN
ap-917	34	16	model	model	NOUN
ap-917	34	17	was	be	AUX
ap-917	34	18	used	use	VERB
ap-917	34	19	[	[	PUNCT
ap-917	34	20	6	6	NUM
ap-917	34	21	]	]	PUNCT
ap-917	34	22	.	.	PUNCT
ap-917	35	1	this	this	DET
ap-917	35	2	model	model	NOUN
ap-917	35	3	consists	consist	VERB
ap-917	35	4	of	of	ADP
ap-917	35	5	gating	gating	NOUN
ap-917	35	6	,	,	PUNCT
ap-917	35	7	calcium	calcium	NOUN
ap-917	35	8	,	,	PUNCT
ap-917	35	9	regulatory	regulatory	ADJ
ap-917	35	10	and	and	CCONJ
ap-917	35	11	contraction	contraction	NOUN
ap-917	35	12	subunits	subunit	NOUN
ap-917	35	13	(	(	PUNCT
ap-917	35	14	fig	fig	NOUN
ap-917	35	15	.	.	PUNCT
ap-917	36	1	2	2	NUM
ap-917	36	2	)	)	PUNCT
ap-917	36	3	.	.	PUNCT
ap-917	37	1	a	a	DET
ap-917	37	2	compartmental	compartmental	ADJ
ap-917	37	3	description	description	NOUN
ap-917	37	4	of	of	ADP
ap-917	37	5	the	the	DET
ap-917	37	6	underlying	underlie	VERB
ap-917	37	7	molecular	molecular	ADJ
ap-917	37	8	processes	process	NOUN
ap-917	37	9	is	be	AUX
ap-917	37	10	adopted	adopt	VERB
ap-917	37	11	to	to	PART
ap-917	37	12	simulate	simulate	VERB
ap-917	37	13	a	a	DET
ap-917	37	14	)	)	PUNCT
ap-917	37	15	calcium	calcium	NOUN
ap-917	37	16	handling	handling	NOUN
ap-917	37	17	,	,	PUNCT
ap-917	37	18	b	b	X
ap-917	37	19	)	)	PUNCT
ap-917	37	20	contraction	contraction	NOUN
ap-917	37	21	control	control	NOUN
ap-917	37	22	by	by	ADP
ap-917	37	23	troponin	troponin	ADJ
ap-917	37	24	,	,	PUNCT
ap-917	37	25	and	and	CCONJ
ap-917	37	26	c	c	X
ap-917	37	27	)	)	PUNCT
ap-917	37	28	the	the	DET
ap-917	37	29	reaction	reaction	NOUN
ap-917	37	30	kinetics	kinetic	NOUN
ap-917	37	31	of	of	ADP
ap-917	37	32	contractile	contractile	NOUN
ap-917	37	33	elements	element	NOUN
ap-917	37	34	.	.	PUNCT
ap-917	38	1	the	the	DET
ap-917	38	2	contraction	contraction	NOUN
ap-917	38	3	model	model	NOUN
ap-917	38	4	and	and	CCONJ
ap-917	38	5	the	the	DET
ap-917	38	6	calcium	calcium	NOUN
ap-917	38	7	handling	handling	NOUN
ap-917	38	8	subunit	subunit	NOUN
ap-917	38	9	were	be	AUX
ap-917	38	10	presented	present	VERB
ap-917	38	11	in	in	ADP
ap-917	38	12	[	[	X
ap-917	38	13	6	6	NUM
ap-917	38	14	]	]	PUNCT
ap-917	38	15	and	and	CCONJ
ap-917	38	16	[	[	X
ap-917	38	17	7	7	NUM
ap-917	38	18	]	]	PUNCT
ap-917	38	19	.	.	PUNCT
ap-917	39	1	unlike	unlike	ADP
ap-917	39	2	the	the	DET
ap-917	39	3	previous	previous	ADJ
ap-917	39	4	models	model	NOUN
ap-917	39	5	,	,	PUNCT
ap-917	39	6	it	it	PRON
ap-917	39	7	also	also	ADV
ap-917	39	8	includes	include	VERB
ap-917	39	9	the	the	DET
ap-917	39	10	na	na	PART
ap-917	39	11	�	�	PROPN
ap-917	39	12	/ca2	/ca2	NOUN
ap-917	39	13	�	�	PROPN
ap-917	39	14	exchanger	exchanger	NOUN
ap-917	39	15	,	,	PUNCT
ap-917	39	16	which	which	PRON
ap-917	39	17	was	be	AUX
ap-917	39	18	omitted	omit	VERB
ap-917	39	19	or	or	CCONJ
ap-917	39	20	extremely	extremely	ADV
ap-917	39	21	simplified	simplified	ADJ
ap-917	39	22	in	in	ADP
ap-917	39	23	earlier	early	ADJ
ap-917	39	24	versions	version	NOUN
ap-917	39	25	.	.	PUNCT
ap-917	40	1	in	in	ADP
ap-917	40	2	principle	principle	NOUN
ap-917	40	3	,	,	PUNCT
ap-917	40	4	ncx	ncx	ADP
ap-917	40	5	current	current	NOUN
ap-917	40	6	is	be	AUX
ap-917	40	7	now	now	ADV
ap-917	40	8	described	describe	VERB
ap-917	40	9	after	after	ADP
ap-917	40	10	winslow	winslow	NOUN
ap-917	40	11	[	[	X
ap-917	40	12	8	8	NUM
ap-917	40	13	]	]	PUNCT
ap-917	40	14	as	as	SCONJ
ap-917	40	15	�	�	PROPN
ap-917	40	16	�	�	PROPN
ap-917	40	17	�	�	PROPN
ap-917	40	18	�	�	PROPN
ap-917	40	19	�	�	PROPN
ap-917	40	20	�	�	PROPN
ap-917	41	1	i	i	PRON
ap-917	41	2	t	t	PROPN
ap-917	41	3	k	k	PROPN
ap-917	41	4	t	t	PROPN
ap-917	41	5	na	na	INTJ
ap-917	41	6	ca	ca	NOUN
ap-917	41	7	e	e	NOUN
ap-917	41	8	na	na	ADP
ap-917	41	9	naca	naca	INTJ
ap-917	42	1	i	i	NOUN
ap-917	42	2	e	e	NOUN
ap-917	42	3	n	n	NOUN
ap-917	42	4	r	r	NOUN
ap-917	42	5	e	e	NOUN
ap-917	42	6	t	t	NOUN
ap-917	42	7	f	f	PROPN
ap-917	42	8	rt	rt	PROPN
ap-917	42	9	e	e	PROPN
ap-917	42	10	(	(	PUNCT
ap-917	42	11	)	)	PUNCT
ap-917	42	12	(	(	PUNCT
ap-917	42	13	)	)	PUNCT
ap-917	42	14	(	(	PUNCT
ap-917	42	15	)	)	PUNCT
ap-917	42	16	(	(	PUNCT
ap-917	42	17	)	)	PUNCT
ap-917	42	18	�	�	PROPN
ap-917	42	19	�	�	PROPN
ap-917	42	20	�	�	PROPN
ap-917	42	21	�	�	PROPN
ap-917	42	22	�	�	PROPN
ap-917	42	23	�	�	PROPN
ap-917	42	24	�	�	PROPN
ap-917	42	25	�	�	PROPN
ap-917	42	26	�	�	PROPN
ap-917	42	27	3	3	NUM
ap-917	42	28	2	2	NUM
ap-917	42	29	3	3	NUM
ap-917	42	30	�	�	PROPN
ap-917	42	31	�	�	PROPN
ap-917	42	32	ca	ca	PROPN
ap-917	42	33	t	t	X
ap-917	42	34	ei	ei	NOUN
ap-917	42	35	n	n	CCONJ
ap-917	42	36	r	r	NOUN
ap-917	42	37	e	e	NOUN
ap-917	42	38	t	t	PROPN
ap-917	42	39	f	f	PROPN
ap-917	42	40	rt	rt	PROPN
ap-917	42	41	(	(	PUNCT
ap-917	42	42	)	)	PUNCT
ap-917	42	43	(	(	PUNCT
ap-917	42	44	)	)	PUNCT
ap-917	42	45	(	(	PUNCT
ap-917	42	46	)	)	PUNCT
ap-917	42	47	(	(	PUNCT
ap-917	42	48	)	)	PUNCT
ap-917	42	49	�	�	PROPN
ap-917	42	50	�	�	PROPN
ap-917	42	51	�	�	PROPN
ap-917	42	52	�	�	PROPN
ap-917	42	53	�	�	PROPN
ap-917	42	54	�	�	PROPN
ap-917	42	55	2	2	NUM
ap-917	42	56	1	1	NUM
ap-917	42	57	and	and	CCONJ
ap-917	42	58	ionic	ionic	ADJ
ap-917	42	59	flux	flux	NOUN
ap-917	42	60	as	as	ADP
ap-917	42	61	q	q	PROPN
ap-917	42	62	t	t	PROPN
ap-917	42	63	a	a	DET
ap-917	42	64	c	c	NOUN
ap-917	42	65	v	v	NOUN
ap-917	42	66	z	z	NOUN
ap-917	43	1	f	f	NOUN
ap-917	44	1	i	i	PRON
ap-917	44	2	tnaca	tnaca	PROPN
ap-917	44	3	cap	cap	VERB
ap-917	44	4	sc	sc	PROPN
ap-917	44	5	c	c	PROPN
ap-917	44	6	naca	naca	PROPN
ap-917	44	7	(	(	PUNCT
ap-917	44	8	)	)	PUNCT
ap-917	44	9	(	(	PUNCT
ap-917	44	10	)	)	PUNCT
ap-917	44	11	�	�	PROPN
ap-917	44	12	�	�	PROPN
ap-917	44	13	�	�	PROPN
ap-917	44	14	�	�	PROPN
ap-917	44	15	,	,	PUNCT
ap-917	44	16	where	where	SCONJ
ap-917	44	17	k(t	k(t	VERB
ap-917	44	18	)	)	PUNCT
ap-917	44	19	is	be	AUX
ap-917	44	20	the	the	DET
ap-917	44	21	saturation	saturation	NOUN
ap-917	44	22	parameter	parameter	NOUN
ap-917	44	23	(	(	PUNCT
ap-917	44	24	see	see	VERB
ap-917	44	25	[	[	X
ap-917	44	26	8	8	NUM
ap-917	44	27	]	]	NUM
ap-917	44	28	)	)	PUNCT
ap-917	44	29	,	,	PUNCT
ap-917	44	30	nai	nai	X
ap-917	44	31	(	(	PUNCT
ap-917	44	32	12	12	NUM
ap-917	44	33	mol	mol	NOUN
ap-917	44	34	/	/	SYM
ap-917	44	35	m3	m3	PROPN
ap-917	44	36	)	)	PUNCT
ap-917	44	37	is	be	AUX
ap-917	44	38	intracellular	intracellular	ADJ
ap-917	44	39	sodium	sodium	NOUN
ap-917	44	40	concentration	concentration	NOUN
ap-917	44	41	,	,	PUNCT
ap-917	44	42	cae	cae	NOUN
ap-917	44	43	(	(	PUNCT
ap-917	44	44	1,8	1,8	PROPN
ap-917	44	45	mol	mol	PROPN
ap-917	44	46	/	/	SYM
ap-917	44	47	m3	m3	PROPN
ap-917	44	48	)	)	PUNCT
ap-917	44	49	is	be	AUX
ap-917	44	50	extracellular	extracellular	ADJ
ap-917	44	51	calcium	calcium	NOUN
ap-917	44	52	concentration	concentration	NOUN
ap-917	44	53	,	,	PUNCT
ap-917	44	54	n	n	CCONJ
ap-917	44	55	(	(	PUNCT
ap-917	44	56	3	3	NUM
ap-917	44	57	)	)	PUNCT
ap-917	45	1	is	be	AUX
ap-917	45	2	stoichiometry	stoichiometry	NOUN
ap-917	45	3	of	of	ADP
ap-917	45	4	na	na	NOUN
ap-917	45	5	-	-	PUNCT
ap-917	45	6	ca	ca	NOUN
ap-917	45	7	exchange	exchange	NOUN
ap-917	45	8	,	,	PUNCT
ap-917	45	9	r	r	NOUN
ap-917	45	10	(	(	PUNCT
ap-917	45	11	0.15	0.15	NUM
ap-917	45	12	)	)	PUNCT
ap-917	45	13	is	be	AUX
ap-917	45	14	position	position	NOUN
ap-917	45	15	of	of	ADP
ap-917	45	16	the	the	DET
ap-917	45	17	peak	peak	NOUN
ap-917	45	18	of	of	ADP
ap-917	45	19	the	the	DET
ap-917	45	20	energy	energy	NOUN
ap-917	45	21	barrier	barrier	NOUN
ap-917	45	22	separating	separate	VERB
ap-917	45	23	two	two	NUM
ap-917	45	24	states	state	NOUN
ap-917	45	25	–	–	PUNCT
ap-917	45	26	activation	activation	NOUN
ap-917	45	27	and	and	CCONJ
ap-917	45	28	deactivation	deactivation	NOUN
ap-917	45	29	of	of	ADP
ap-917	45	30	the	the	DET
ap-917	45	31	exchanger	exchanger	NOUN
ap-917	45	32	,	,	PUNCT
ap-917	45	33	e(t	e(t	PROPN
ap-917	45	34	)	)	PUNCT
ap-917	45	35	is	be	AUX
ap-917	45	36	action	action	NOUN
ap-917	45	37	potential	potential	NOUN
ap-917	45	38	,	,	PUNCT
ap-917	46	1	f	f	PROPN
ap-917	46	2	(	(	PUNCT
ap-917	46	3	96485.3415	96485.3415	NOUN
ap-917	46	4	s	s	VERB
ap-917	46	5	�	�	PROPN
ap-917	46	6	a	a	NOUN
ap-917	46	7	/	/	SYM
ap-917	46	8	mol	mol	NOUN
ap-917	46	9	)	)	PUNCT
ap-917	46	10	is	be	AUX
ap-917	46	11	faraday	faraday	PROPN
ap-917	46	12	constant	constant	ADJ
ap-917	46	13	,	,	PUNCT
ap-917	46	14	r	r	NOUN
ap-917	46	15	(	(	PUNCT
ap-917	46	16	8.3144	8.3144	NUM
ap-917	46	17	j	j	PROPN
ap-917	46	18	/	/	SYM
ap-917	46	19	k	k	PROPN
ap-917	46	20	�	�	PROPN
ap-917	46	21	mol	mol	NOUN
ap-917	46	22	)	)	PUNCT
ap-917	46	23	is	be	AUX
ap-917	46	24	ideal	ideal	ADJ
ap-917	46	25	gas	gas	NOUN
ap-917	46	26	constant	constant	NOUN
ap-917	46	27	,	,	PUNCT
ap-917	46	28	t	t	PROPN
ap-917	46	29	(	(	PUNCT
ap-917	46	30	290.15	290.15	NUM
ap-917	46	31	k	k	NOUN
ap-917	46	32	)	)	PUNCT
ap-917	46	33	is	be	AUX
ap-917	46	34	absolute	absolute	ADJ
ap-917	46	35	temperature	temperature	NOUN
ap-917	46	36	,	,	PUNCT
ap-917	46	37	nae	nae	PROPN
ap-917	46	38	(	(	PUNCT
ap-917	46	39	140	140	NUM
ap-917	46	40	mol	mol	PROPN
ap-917	46	41	/	/	SYM
ap-917	46	42	m3	m3	PROPN
ap-917	46	43	)	)	PUNCT
ap-917	47	1	is	be	AUX
ap-917	47	2	extracellular	extracellular	ADJ
ap-917	47	3	sodium	sodium	NOUN
ap-917	47	4	concentration	concentration	NOUN
ap-917	47	5	,	,	PUNCT
ap-917	47	6	cai(t	cai(t	PROPN
ap-917	47	7	)	)	PUNCT
ap-917	47	8	is	be	AUX
ap-917	47	9	intracellular	intracellular	ADJ
ap-917	47	10	calcium	calcium	NOUN
ap-917	47	11	concentration	concentration	NOUN
ap-917	47	12	,	,	PUNCT
ap-917	47	13	acap	acap	NOUN
ap-917	47	14	(	(	PUNCT
ap-917	47	15	1.534	1.534	NUM
ap-917	47	16	e	e	NOUN
ap-917	47	17	8	8	NUM
ap-917	47	18	m2	m2	NOUN
ap-917	47	19	)	)	PUNCT
ap-917	48	1	is	be	AUX
ap-917	48	2	capacitive	capacitive	ADJ
ap-917	48	3	membrane	membrane	NOUN
ap-917	48	4	area	area	NOUN
ap-917	48	5	,	,	PUNCT
ap-917	48	6	csc	csc	PROPN
ap-917	48	7	(	(	PUNCT
ap-917	48	8	1	1	NUM
ap-917	48	9	f	f	PROPN
ap-917	48	10	/	/	SYM
ap-917	48	11	m2	m2	PROPN
ap-917	48	12	)	)	PUNCT
ap-917	48	13	is	be	AUX
ap-917	48	14	specific	specific	ADJ
ap-917	48	15	membrane	membrane	NOUN
ap-917	48	16	capacity	capacity	NOUN
ap-917	48	17	,	,	PUNCT
ap-917	48	18	vc	vc	PROPN
ap-917	48	19	(	(	PUNCT
ap-917	48	20	25	25	NUM
ap-917	48	21	e	e	NOUN
ap-917	48	22	12	12	NUM
ap-917	48	23	m3	m3	PROPN
ap-917	48	24	)	)	PUNCT
ap-917	48	25	is	be	AUX
ap-917	48	26	cellular	cellular	ADJ
ap-917	48	27	volume	volume	NOUN
ap-917	48	28	,	,	PUNCT
ap-917	48	29	and	and	CCONJ
ap-917	48	30	z	z	NOUN
ap-917	48	31	(	(	PUNCT
ap-917	48	32	2	2	NUM
ap-917	48	33	)	)	PUNCT
ap-917	48	34	is	be	AUX
ap-917	48	35	valence	valence	NOUN
ap-917	48	36	of	of	ADP
ap-917	48	37	calcium	calcium	NOUN
ap-917	48	38	ion	ion	NOUN
ap-917	48	39	.	.	PUNCT
ap-917	49	1	2.2	2.2	NUM
ap-917	49	2	simulation	simulation	NOUN
ap-917	49	3	and	and	CCONJ
ap-917	49	4	parameters	parameter	NOUN
ap-917	49	5	the	the	DET
ap-917	49	6	model	model	NOUN
ap-917	49	7	was	be	AUX
ap-917	49	8	implemented	implement	VERB
ap-917	49	9	in	in	ADP
ap-917	49	10	matlab	matlab	PROPN
ap-917	49	11	/	/	SYM
ap-917	49	12	simulink	simulink	PROPN
ap-917	49	13	.	.	PUNCT
ap-917	50	1	the	the	DET
ap-917	50	2	ode15s	ode15s	ADJ
ap-917	50	3	(	(	PUNCT
ap-917	50	4	stiff	stiff	ADJ
ap-917	50	5	/	/	SYM
ap-917	50	6	ndf	ndf	NOUN
ap-917	50	7	)	)	PUNCT
ap-917	50	8	integration	integration	NOUN
ap-917	50	9	method	method	NOUN
ap-917	50	10	was	be	AUX
ap-917	50	11	used	use	VERB
ap-917	50	12	.	.	PUNCT
ap-917	51	1	as	as	ADP
ap-917	51	2	an	an	DET
ap-917	51	3	input	input	NOUN
ap-917	51	4	,	,	PUNCT
ap-917	51	5	the	the	DET
ap-917	51	6	experimentally	experimentally	ADV
ap-917	51	7	obtained	obtain	VERB
ap-917	51	8	trace	trace	NOUN
ap-917	51	9	of	of	ADP
ap-917	51	10	cardiac	cardiac	ADJ
ap-917	51	11	action	action	NOUN
ap-917	51	12	potential	potential	NOUN
ap-917	51	13	was	be	AUX
ap-917	51	14	used	use	VERB
ap-917	51	15	(	(	PUNCT
ap-917	51	16	fig	fig	NOUN
ap-917	51	17	.	.	PUNCT
ap-917	52	1	3	3	X
ap-917	52	2	)	)	PUNCT
ap-917	53	1	[	[	X
ap-917	53	2	9	9	NUM
ap-917	53	3	]	]	PUNCT
ap-917	53	4	.	.	PUNCT
ap-917	54	1	simulation	simulation	NOUN
ap-917	54	2	parameters	parameter	NOUN
ap-917	54	3	:	:	PUNCT
ap-917	54	4	stimulation	stimulation	NOUN
ap-917	54	5	frequencies	frequency	NOUN
ap-917	54	6	1.2	1.2	NUM
ap-917	54	7	and	and	CCONJ
ap-917	54	8	3	3	NUM
ap-917	54	9	hz	hz	NOUN
ap-917	54	10	,	,	PUNCT
ap-917	54	11	simulation	simulation	NOUN
ap-917	54	12	duration	duration	NOUN
ap-917	54	13	300	300	NUM
ap-917	54	14	s	s	NOUN
ap-917	54	15	(	(	PUNCT
ap-917	54	16	to	to	PART
ap-917	54	17	avoid	avoid	VERB
ap-917	54	18	transient	transient	ADJ
ap-917	54	19	state	state	NOUN
ap-917	54	20	effects	effect	NOUN
ap-917	54	21	)	)	PUNCT
ap-917	54	22	.	.	PUNCT
ap-917	55	1	the	the	DET
ap-917	55	2	model	model	NOUN
ap-917	55	3	was	be	AUX
ap-917	55	4	also	also	ADV
ap-917	55	5	verified	verify	VERB
ap-917	55	6	for	for	ADP
ap-917	55	7	various	various	ADJ
ap-917	55	8	action	action	NOUN
ap-917	55	9	potential	potential	ADJ
ap-917	55	10	durations	duration	NOUN
ap-917	55	11	(	(	PUNCT
ap-917	55	12	apd	apd	PROPN
ap-917	55	13	)	)	PUNCT
ap-917	55	14	in	in	ADP
ap-917	55	15	accordance	accordance	NOUN
ap-917	55	16	with	with	ADP
ap-917	55	17	reality	reality	NOUN
ap-917	55	18	where	where	SCONJ
ap-917	55	19	apd	apd	PROPN
ap-917	55	20	varies	vary	VERB
ap-917	55	21	physiologically	physiologically	ADV
ap-917	55	22	both	both	CCONJ
ap-917	55	23	with	with	ADP
ap-917	55	24	heart	heart	NOUN
ap-917	55	25	rate	rate	NOUN
ap-917	55	26	and	and	CCONJ
ap-917	55	27	in	in	ADP
ap-917	55	28	various	various	ADJ
ap-917	55	29	regions	region	NOUN
ap-917	55	30	of	of	ADP
ap-917	55	31	the	the	DET
ap-917	55	32	myocardium	myocardium	NOUN
ap-917	55	33	.	.	PUNCT
ap-917	56	1	however	however	ADV
ap-917	56	2	,	,	PUNCT
ap-917	56	3	due	due	ADP
ap-917	56	4	to	to	ADP
ap-917	56	5	the	the	DET
ap-917	56	6	simplicity	simplicity	NOUN
ap-917	56	7	,	,	PUNCT
ap-917	56	8	of	of	ADP
ap-917	56	9	the	the	DET
ap-917	56	10	model	model	NOUN
ap-917	56	11	,	,	PUNCT
ap-917	56	12	it	it	PRON
ap-917	56	13	currently	currently	ADV
ap-917	56	14	does	do	AUX
ap-917	56	15	not	not	PART
ap-917	56	16	essentially	essentially	ADV
ap-917	56	17	reflect	reflect	VERB
ap-917	56	18	any	any	DET
ap-917	56	19	mechanisms	mechanism	NOUN
ap-917	56	20	influencing	influence	VERB
ap-917	56	21	the	the	DET
ap-917	56	22	shaping	shaping	NOUN
ap-917	56	23	and	and	CCONJ
ap-917	56	24	action	action	NOUN
ap-917	56	25	potential	potential	ADJ
ap-917	56	26	duration	duration	NOUN
ap-917	56	27	,	,	PUNCT
ap-917	56	28	such	such	ADJ
ap-917	56	29	as	as	ADP
ap-917	56	30	modification	modification	NOUN
ap-917	56	31	of	of	ADP
ap-917	56	32	the	the	DET
ap-917	56	33	activity	activity	NOUN
ap-917	56	34	of	of	ADP
ap-917	56	35	ionic	ionic	ADJ
ap-917	56	36	channels	channel	NOUN
ap-917	56	37	.	.	PUNCT
ap-917	57	1	heart	heart	NOUN
ap-917	57	2	failure	failure	NOUN
ap-917	57	3	model	model	NOUN
ap-917	57	4	:	:	PUNCT
ap-917	57	5	chronic	chronic	ADJ
ap-917	57	6	congestive	congestive	NOUN
ap-917	57	7	failure	failure	NOUN
ap-917	57	8	was	be	AUX
ap-917	57	9	simulated	simulate	VERB
ap-917	57	10	according	accord	VERB
ap-917	57	11	to	to	ADP
ap-917	57	12	experimental	experimental	ADJ
ap-917	57	13	findings	finding	NOUN
ap-917	58	1	[	[	X
ap-917	58	2	10	10	NUM
ap-917	58	3	]	]	PUNCT
ap-917	58	4	by	by	ADP
ap-917	58	5	reducing	reduce	VERB
ap-917	58	6	the	the	DET
ap-917	58	7	activity	activity	NOUN
ap-917	58	8	of	of	ADP
ap-917	58	9	serca	serca	NOUN
ap-917	58	10	from	from	ADP
ap-917	58	11	100	100	NUM
ap-917	58	12	%	%	NOUN
ap-917	58	13	to	to	ADP
ap-917	58	14	75	75	NUM
ap-917	58	15	and	and	CCONJ
ap-917	58	16	50	50	NUM
ap-917	58	17	%	%	NOUN
ap-917	58	18	of	of	ADP
ap-917	58	19	normal	normal	ADJ
ap-917	58	20	values	value	NOUN
ap-917	58	21	.	.	PUNCT
ap-917	59	1	serca	serca	PROPN
ap-917	59	2	ionic	ionic	ADJ
ap-917	59	3	flux	flux	NOUN
ap-917	59	4	is	be	AUX
ap-917	59	5	defined	define	VERB
ap-917	59	6	by	by	ADP
ap-917	59	7	the	the	DET
ap-917	59	8	equation	equation	NOUN
ap-917	59	9	q	q	PROPN
ap-917	59	10	t	t	PROPN
ap-917	59	11	ca	can	AUX
ap-917	59	12	t	t	PROPN
ap-917	59	13	ca	can	AUX
ap-917	60	1	k	k	PROPN
ap-917	60	2	k	k	PROPN
ap-917	60	3	f	f	PROPN
ap-917	61	1	tin	tin	INTJ
ap-917	62	1	i	i	PRON
ap-917	63	1	i	i	PROPN
ap-917	63	2	in	in	ADP
ap-917	63	3	inact	inact	PROPN
ap-917	63	4	(	(	PUNCT
ap-917	63	5	)	)	PUNCT
ap-917	63	6	(	(	PUNCT
ap-917	63	7	(	(	PUNCT
ap-917	63	8	)	)	PUNCT
ap-917	63	9	)	)	PUNCT
ap-917	64	1	(	(	PUNCT
ap-917	64	2	(	(	PUNCT
ap-917	64	3	)	)	PUNCT
ap-917	64	4	)	)	PUNCT
ap-917	64	5	�	�	PROPN
ap-917	64	6	�	�	PROPN
ap-917	64	7	�	�	PROPN
ap-917	64	8	�	�	PROPN
ap-917	64	9	�	�	PROPN
ap-917	64	10	0	0	NUM
ap-917	64	11	,	,	PUNCT
ap-917	64	12	where	where	SCONJ
ap-917	64	13	qin(t	qin(t	NOUN
ap-917	64	14	)	)	PUNCT
ap-917	64	15	is	be	AUX
ap-917	64	16	ionic	ionic	ADJ
ap-917	64	17	flux	flux	NOUN
ap-917	64	18	from	from	ADP
ap-917	64	19	the	the	DET
ap-917	64	20	intracellular	intracellular	ADJ
ap-917	64	21	space	space	NOUN
ap-917	64	22	to	to	ADP
ap-917	64	23	the	the	DET
ap-917	64	24	network	network	NOUN
ap-917	64	25	sarcoplasmic	sarcoplasmic	NOUN
ap-917	64	26	reticulum	reticulum	NOUN
ap-917	64	27	(	(	PUNCT
ap-917	64	28	nsr	nsr	NOUN
ap-917	64	29	)	)	PUNCT
ap-917	64	30	,	,	PUNCT
ap-917	64	31	4	4	NUM
ap-917	64	32	©	©	PROPN
ap-917	64	33	czech	czech	PROPN
ap-917	64	34	technical	technical	PROPN
ap-917	64	35	university	university	PROPN
ap-917	64	36	publishing	publishing	NOUN
ap-917	64	37	house	house	NOUN
ap-917	64	38	http://ctn.cvut.cz/ap/	http://ctn.cvut.cz/ap/	PROPN
ap-917	64	39	acta	acta	PROPN
ap-917	64	40	polytechnica	polytechnica	PROPN
ap-917	64	41	vol	vol	NOUN
ap-917	64	42	.	.	PUNCT
ap-917	65	1	48	48	NUM
ap-917	65	2	no	no	NOUN
ap-917	65	3	.	.	PUNCT
ap-917	66	1	1/2008	1/2008	NUM
ap-917	66	2	e	e	NOUN
ap-917	66	3	t	t	PROPN
ap-917	66	4	(	(	PUNCT
ap-917	66	5	)	)	PUNCT
ap-917	66	6	fig	fig	NOUN
ap-917	66	7	.	.	PUNCT
ap-917	67	1	2	2	NUM
ap-917	67	2	:	:	PUNCT
ap-917	67	3	model	model	NOUN
ap-917	67	4	scheme	scheme	NOUN
ap-917	67	5	–	–	PUNCT
ap-917	67	6	subunits	subunit	NOUN
ap-917	67	7	interaction	interaction	NOUN
ap-917	67	8	fig	fig	NOUN
ap-917	67	9	.	.	PUNCT
ap-917	68	1	3	3	NUM
ap-917	68	2	:	:	PUNCT
ap-917	68	3	action	action	NOUN
ap-917	68	4	potential	potential	NOUN
ap-917	68	5	–	–	PUNCT
ap-917	68	6	model	model	NOUN
ap-917	68	7	input	input	NOUN
ap-917	68	8	cai0	cai0	PROPN
ap-917	68	9	(	(	PUNCT
ap-917	68	10	1	1	NUM
ap-917	68	11	e	e	SYM
ap-917	68	12	4	4	NUM
ap-917	68	13	mol	mol	NOUN
ap-917	68	14	/	/	SYM
ap-917	68	15	m3	m3	PROPN
ap-917	68	16	)	)	PUNCT
ap-917	68	17	is	be	AUX
ap-917	68	18	initial	initial	ADJ
ap-917	68	19	intracellular	intracellular	ADJ
ap-917	68	20	calcium	calcium	NOUN
ap-917	68	21	concentration	concentration	NOUN
ap-917	68	22	,	,	PUNCT
ap-917	68	23	kin	kin	X
ap-917	68	24	(	(	PUNCT
ap-917	68	25	4	4	NUM
ap-917	68	26	s	s	NOUN
ap-917	68	27	1	1	NUM
ap-917	68	28	)	)	PUNCT
ap-917	68	29	is	be	AUX
ap-917	68	30	the	the	DET
ap-917	68	31	rate	rate	NOUN
ap-917	68	32	constant	constant	ADJ
ap-917	68	33	of	of	ADP
ap-917	68	34	the	the	DET
ap-917	68	35	passive	passive	ADJ
ap-917	68	36	part	part	NOUN
ap-917	68	37	of	of	ADP
ap-917	68	38	serca	serca	PROPN
ap-917	68	39	channel	channel	PROPN
ap-917	68	40	,	,	PUNCT
ap-917	68	41	kinact	kinact	NOUN
ap-917	68	42	(	(	PUNCT
ap-917	68	43	1	1	NUM
ap-917	68	44	s	s	NOUN
ap-917	68	45	1	1	NUM
ap-917	68	46	)	)	PUNCT
ap-917	68	47	is	be	AUX
ap-917	68	48	the	the	DET
ap-917	68	49	rate	rate	NOUN
ap-917	68	50	constant	constant	ADJ
ap-917	68	51	of	of	ADP
ap-917	68	52	the	the	DET
ap-917	68	53	active	active	ADJ
ap-917	68	54	part	part	NOUN
ap-917	68	55	of	of	ADP
ap-917	68	56	the	the	DET
ap-917	68	57	serca	serca	PROPN
ap-917	68	58	channel	channel	NOUN
ap-917	68	59	,	,	PUNCT
ap-917	68	60	and	and	CCONJ
ap-917	68	61	f	f	X
ap-917	68	62	�	�	PROPN
ap-917	68	63	(t	(t	NOUN
ap-917	68	64	)	)	PUNCT
ap-917	68	65	is	be	AUX
ap-917	68	66	steady	steady	ADJ
ap-917	68	67	-	-	PUNCT
ap-917	68	68	state	state	NOUN
ap-917	68	69	deactivation	deactivation	NOUN
ap-917	68	70	coefficient	coefficient	NOUN
ap-917	68	71	.	.	PUNCT
ap-917	69	1	according	accord	VERB
ap-917	69	2	to	to	ADP
ap-917	69	3	some	some	DET
ap-917	69	4	findings	finding	NOUN
ap-917	69	5	that	that	PRON
ap-917	69	6	report	report	VERB
ap-917	69	7	ncx	ncx	ADP
ap-917	69	8	activity	activity	NOUN
ap-917	69	9	in	in	ADP
ap-917	69	10	failing	fail	VERB
ap-917	69	11	hearts	heart	NOUN
ap-917	69	12	[	[	X
ap-917	69	13	11	11	NUM
ap-917	69	14	]	]	PUNCT
ap-917	69	15	,	,	PUNCT
ap-917	69	16	the	the	DET
ap-917	69	17	ncx	ncx	ADJ
ap-917	69	18	activity	activity	NOUN
ap-917	69	19	was	be	AUX
ap-917	69	20	varied	varied	ADJ
ap-917	69	21	between	between	ADP
ap-917	69	22	50	50	NUM
ap-917	69	23	,	,	PUNCT
ap-917	69	24	75	75	NUM
ap-917	69	25	,	,	PUNCT
ap-917	69	26	100	100	NUM
ap-917	69	27	and	and	CCONJ
ap-917	69	28	130	130	NUM
ap-917	69	29	%	%	NOUN
ap-917	69	30	of	of	ADP
ap-917	69	31	normal	normal	ADJ
ap-917	69	32	activity	activity	NOUN
ap-917	69	33	.	.	PUNCT
ap-917	70	1	the	the	DET
ap-917	70	2	ncx	ncx	ADJ
ap-917	70	3	transporter	transporter	NOUN
ap-917	70	4	was	be	AUX
ap-917	70	5	also	also	ADV
ap-917	70	6	virtually	virtually	ADV
ap-917	70	7	completely	completely	ADV
ap-917	70	8	blocked	block	VERB
ap-917	70	9	(	(	PUNCT
ap-917	70	10	activity	activity	NOUN
ap-917	70	11	set	set	VERB
ap-917	70	12	to	to	ADP
ap-917	70	13	0	0	NUM
ap-917	70	14	%	%	NOUN
ap-917	70	15	)	)	PUNCT
ap-917	70	16	,	,	PUNCT
ap-917	70	17	so	so	SCONJ
ap-917	70	18	that	that	SCONJ
ap-917	70	19	its	its	PRON
ap-917	70	20	(	(	PUNCT
ap-917	70	21	missing	missing	ADJ
ap-917	70	22	)	)	PUNCT
ap-917	70	23	role	role	NOUN
ap-917	70	24	in	in	ADP
ap-917	70	25	ecc	ecc	PROPN
ap-917	70	26	could	could	AUX
ap-917	70	27	be	be	AUX
ap-917	70	28	identified	identify	VERB
ap-917	70	29	more	more	ADV
ap-917	70	30	easily	easily	ADV
ap-917	70	31	.	.	PUNCT
ap-917	71	1	3	3	NUM
ap-917	71	2	results	result	VERB
ap-917	71	3	3.1	3.1	NUM
ap-917	71	4	ncx	ncx	NOUN
ap-917	71	5	in	in	ADP
ap-917	71	6	a	a	DET
ap-917	71	7	non	non	ADJ
ap-917	71	8	-	-	ADJ
ap-917	71	9	failing	failing	ADJ
ap-917	71	10	heart	heart	NOUN
ap-917	71	11	(	(	PUNCT
ap-917	71	12	nf	nf	INTJ
ap-917	71	13	)	)	PUNCT
ap-917	71	14	though	though	SCONJ
ap-917	71	15	ncx	ncx	NOUN
ap-917	71	16	is	be	AUX
ap-917	71	17	a	a	DET
ap-917	71	18	minor	minor	ADJ
ap-917	71	19	calcium	calcium	NOUN
ap-917	71	20	-	-	PUNCT
ap-917	71	21	removal	removal	NOUN
ap-917	71	22	mechanism	mechanism	NOUN
ap-917	71	23	(	(	PUNCT
ap-917	71	24	10~25	10~25	NUM
ap-917	71	25	%	%	NOUN
ap-917	71	26	of	of	ADP
ap-917	71	27	total	total	NOUN
ap-917	71	28	ca	ca	NOUN
ap-917	71	29	to	to	PART
ap-917	71	30	be	be	AUX
ap-917	71	31	removed	remove	VERB
ap-917	71	32	)	)	PUNCT
ap-917	71	33	,	,	PUNCT
ap-917	71	34	its	its	PRON
ap-917	71	35	contribution	contribution	NOUN
ap-917	71	36	to	to	ADP
ap-917	71	37	calcium	calcium	NOUN
ap-917	71	38	handling	handling	NOUN
ap-917	71	39	is	be	AUX
ap-917	71	40	substantial	substantial	ADJ
ap-917	71	41	and	and	CCONJ
ap-917	71	42	becomes	become	VERB
ap-917	71	43	obvious	obvious	ADJ
ap-917	71	44	over	over	ADP
ap-917	71	45	a	a	DET
ap-917	71	46	period	period	NOUN
ap-917	71	47	of	of	ADP
ap-917	71	48	time	time	NOUN
ap-917	71	49	(	(	PUNCT
ap-917	71	50	here	here	ADV
ap-917	71	51	,	,	PUNCT
ap-917	71	52	after	after	ADP
ap-917	71	53	300	300	NUM
ap-917	71	54	s	s	NOUN
ap-917	71	55	at	at	ADP
ap-917	71	56	1	1	NUM
ap-917	71	57	hz	hz	NOUN
ap-917	71	58	)	)	PUNCT
ap-917	71	59	.	.	PUNCT
ap-917	72	1	the	the	DET
ap-917	72	2	absence	absence	NOUN
ap-917	72	3	of	of	ADP
ap-917	72	4	ncx	ncx	ADJ
ap-917	72	5	activity	activity	NOUN
ap-917	72	6	(	(	PUNCT
ap-917	72	7	fig	fig	NOUN
ap-917	72	8	.	.	PUNCT
ap-917	73	1	4	4	X
ap-917	73	2	)	)	PUNCT
ap-917	73	3	results	result	NOUN
ap-917	73	4	in	in	ADP
ap-917	73	5	more	more	ADJ
ap-917	73	6	ca2	ca2	PROPN
ap-917	73	7	�	�	PROPN
ap-917	73	8	remaining	remain	VERB
ap-917	73	9	in	in	ADP
ap-917	73	10	the	the	DET
ap-917	73	11	cell	cell	NOUN
ap-917	73	12	.	.	PUNCT
ap-917	74	1	this	this	DET
ap-917	74	2	calcium	calcium	NOUN
ap-917	74	3	is	be	AUX
ap-917	74	4	transported	transport	VERB
ap-917	74	5	into	into	ADP
ap-917	74	6	internal	internal	ADJ
ap-917	74	7	stores	store	NOUN
ap-917	74	8	(	(	PUNCT
ap-917	74	9	the	the	DET
ap-917	74	10	sarcoplasmic	sarcoplasmic	ADJ
ap-917	74	11	reticulum	reticulum	NOUN
ap-917	74	12	)	)	PUNCT
ap-917	74	13	by	by	ADP
ap-917	74	14	the	the	DET
ap-917	74	15	serca	serca	NOUN
ap-917	74	16	transporter	transporter	NOUN
ap-917	74	17	.	.	PUNCT
ap-917	75	1	even	even	ADV
ap-917	75	2	the	the	DET
ap-917	75	3	rather	rather	ADV
ap-917	75	4	small	small	ADJ
ap-917	75	5	amount	amount	NOUN
ap-917	75	6	of	of	ADP
ap-917	75	7	ca2	ca2	PROPN
ap-917	75	8	�	�	PROPN
ap-917	75	9	that	that	PRON
ap-917	75	10	is	be	AUX
ap-917	75	11	retained	retain	VERB
ap-917	75	12	during	during	ADP
ap-917	75	13	each	each	DET
ap-917	75	14	beat	beat	NOUN
ap-917	75	15	gradually	gradually	ADV
ap-917	75	16	loads	load	VERB
ap-917	75	17	the	the	DET
ap-917	75	18	internal	internal	ADJ
ap-917	75	19	calcium	calcium	NOUN
ap-917	75	20	stores	store	NOUN
ap-917	75	21	until	until	SCONJ
ap-917	75	22	a	a	DET
ap-917	75	23	new	new	ADJ
ap-917	75	24	input	input	NOUN
ap-917	75	25	-	-	PUNCT
ap-917	75	26	output	output	NOUN
ap-917	75	27	©	©	PROPN
ap-917	75	28	czech	czech	PROPN
ap-917	75	29	technical	technical	PROPN
ap-917	75	30	university	university	PROPN
ap-917	75	31	publishing	publishing	NOUN
ap-917	75	32	house	house	NOUN
ap-917	75	33	http://ctn.cvut.cz/ap/	http://ctn.cvut.cz/ap/	PROPN
ap-917	75	34	5	5	NUM
ap-917	75	35	acta	acta	PROPN
ap-917	75	36	polytechnica	polytechnica	PROPN
ap-917	75	37	vol	vol	NOUN
ap-917	75	38	.	.	PUNCT
ap-917	76	1	48	48	NUM
ap-917	76	2	no	no	NOUN
ap-917	76	3	.	.	PROPN
ap-917	77	1	1/2008	1/2008	NUM
ap-917	77	2	cai	cai	X
ap-917	77	3	(	(	PUNCT
ap-917	77	4	f	f	X
ap-917	77	5	)	)	PUNCT
ap-917	77	6	0	0	NUM
ap-917	77	7	00e+00	00e+00	NUM
ap-917	77	8	.	.	NOUN
ap-917	77	9	1	1	NUM
ap-917	77	10	00e-04	00e-04	NUM
ap-917	77	11	.	.	PUNCT
ap-917	77	12	2	2	NUM
ap-917	77	13	00e-04	00e-04	NUM
ap-917	77	14	.	.	PUNCT
ap-917	78	1	3.00e-04	3.00e-04	NUM
ap-917	78	2	299	299	NUM
ap-917	78	3	00	00	NUM
ap-917	78	4	.	.	PUNCT
ap-917	79	1	299	299	NUM
ap-917	79	2	25	25	NUM
ap-917	79	3	.	.	PUNCT
ap-917	80	1	299	299	NUM
ap-917	80	2	50	50	NUM
ap-917	80	3	.	.	PUNCT
ap-917	81	1	299	299	NUM
ap-917	81	2	75	75	NUM
ap-917	81	3	.	.	PUNCT
ap-917	82	1	300	300	NUM
ap-917	82	2	00	00	NUM
ap-917	82	3	.	.	PUNCT
ap-917	83	1	time	time	NOUN
ap-917	83	2	(	(	PUNCT
ap-917	83	3	s	s	X
ap-917	83	4	)	)	PUNCT
ap-917	83	5	c	c	NOUN
ap-917	83	6	a	a	DET
ap-917	83	7	i	i	NOUN
ap-917	83	8	(	(	PUNCT
ap-917	83	9	m	m	PROPN
ap-917	83	10	o	o	NOUN
ap-917	83	11	l	l	NOUN
ap-917	83	12	)	)	PUNCT
ap-917	83	13	norm	norm	NOUN
ap-917	83	14	no	no	DET
ap-917	83	15	ncx	ncx	NOUN
ap-917	83	16	ncx	ncx	ADV
ap-917	83	17	150	150	NUM
ap-917	83	18	fig	fig	NOUN
ap-917	83	19	.	.	PUNCT
ap-917	84	1	4	4	NUM
ap-917	84	2	:	:	PUNCT
ap-917	84	3	intracellular	intracellular	ADJ
ap-917	84	4	ca2	ca2	PROPN
ap-917	84	5	�	�	PROPN
ap-917	84	6	concentration	concentration	NOUN
ap-917	84	7	in	in	ADP
ap-917	84	8	nf	nf	NOUN
ap-917	84	9	and	and	CCONJ
ap-917	84	10	f	f	PROPN
ap-917	84	11	heart	heart	NOUN
ap-917	84	12	(	(	PUNCT
ap-917	84	13	ncx	ncx	ADP
ap-917	84	14	activity	activity	NOUN
ap-917	84	15	0	0	NUM
ap-917	84	16	%	%	NOUN
ap-917	84	17	and	and	CCONJ
ap-917	84	18	150	150	NUM
ap-917	84	19	%	%	NOUN
ap-917	84	20	)	)	PUNCT
ap-917	84	21	,	,	PUNCT
ap-917	84	22	at	at	ADP
ap-917	84	23	1	1	NUM
ap-917	84	24	hz	hz	VERB
ap-917	84	25	am	be	AUX
ap-917	84	26	0	0	NUM
ap-917	84	27	00e+00	00e+00	NUM
ap-917	84	28	.	.	PUNCT
ap-917	85	1	5	5	NUM
ap-917	85	2	00e-09	00e-09	NOUN
ap-917	85	3	.	.	PUNCT
ap-917	86	1	1	1	NUM
ap-917	86	2	00e-08	00e-08	NOUN
ap-917	86	3	.	.	PUNCT
ap-917	87	1	1	1	NUM
ap-917	87	2	50e-08	50e-08	NUM
ap-917	87	3	.	.	PUNCT
ap-917	88	1	2.00e-08	2.00e-08	NUM
ap-917	88	2	299	299	NUM
ap-917	88	3	00	00	NUM
ap-917	88	4	.	.	PUNCT
ap-917	89	1	299	299	NUM
ap-917	89	2	25	25	NUM
ap-917	89	3	.	.	PUNCT
ap-917	90	1	299	299	NUM
ap-917	90	2	50	50	NUM
ap-917	90	3	.	.	PUNCT
ap-917	91	1	299	299	NUM
ap-917	91	2	75	75	NUM
ap-917	91	3	.	.	PUNCT
ap-917	92	1	300	300	NUM
ap-917	92	2	00	00	NUM
ap-917	92	3	.	.	PUNCT
ap-917	93	1	time	time	NOUN
ap-917	93	2	(	(	PUNCT
ap-917	93	3	s	s	X
ap-917	93	4	)	)	PUNCT
ap-917	93	5	a	a	DET
ap-917	93	6	m	m	PROPN
ap-917	93	7	(	(	PUNCT
ap-917	93	8	m	m	PROPN
ap-917	93	9	o	o	NOUN
ap-917	93	10	l	l	NOUN
ap-917	93	11	)	)	PUNCT
ap-917	93	12	norm	norm	NOUN
ap-917	93	13	no	no	DET
ap-917	93	14	ncx	ncx	ADJ
ap-917	93	15	fig	fig	NOUN
ap-917	93	16	.	.	PUNCT
ap-917	94	1	5	5	NUM
ap-917	94	2	:	:	PUNCT
ap-917	94	3	contractile	contractile	NOUN
ap-917	94	4	force	force	NOUN
ap-917	94	5	in	in	ADP
ap-917	94	6	nf	nf	ADJ
ap-917	94	7	heart	heart	NOUN
ap-917	94	8	and	and	CCONJ
ap-917	94	9	in	in	ADP
ap-917	94	10	heart	heart	NOUN
ap-917	94	11	with	with	ADP
ap-917	94	12	turned	turn	VERB
ap-917	94	13	ncx	ncx	ADP
ap-917	94	14	off	off	ADP
ap-917	94	15	,	,	PUNCT
ap-917	94	16	at	at	ADP
ap-917	94	17	1	1	NUM
ap-917	94	18	hz	hz	NOUN
ap-917	94	19	equilibrium	equilibrium	NOUN
ap-917	94	20	is	be	AUX
ap-917	94	21	reached	reach	VERB
ap-917	94	22	.	.	PUNCT
ap-917	95	1	thus	thus	ADV
ap-917	95	2	during	during	ADP
ap-917	95	3	activation	activation	NOUN
ap-917	95	4	more	more	ADJ
ap-917	95	5	ca2	ca2	PROPN
ap-917	95	6	�	�	PROPN
ap-917	95	7	will	will	AUX
ap-917	95	8	be	be	AUX
ap-917	95	9	released	release	VERB
ap-917	95	10	and	and	CCONJ
ap-917	95	11	so	so	ADV
ap-917	95	12	more	more	ADJ
ap-917	95	13	force	force	NOUN
ap-917	95	14	will	will	AUX
ap-917	95	15	be	be	AUX
ap-917	95	16	generated	generate	VERB
ap-917	95	17	.	.	PUNCT
ap-917	96	1	at	at	ADP
ap-917	96	2	the	the	DET
ap-917	96	3	same	same	ADJ
ap-917	96	4	time	time	NOUN
ap-917	96	5	,	,	PUNCT
ap-917	96	6	the	the	DET
ap-917	96	7	relaxation	relaxation	NOUN
ap-917	96	8	of	of	ADP
ap-917	96	9	contraction	contraction	NOUN
ap-917	96	10	is	be	AUX
ap-917	96	11	prolonged	prolong	VERB
ap-917	96	12	.	.	PUNCT
ap-917	97	1	increased	increase	VERB
ap-917	97	2	ncx	ncx	ADP
ap-917	97	3	activity	activity	NOUN
ap-917	97	4	exhibits	exhibit	VERB
ap-917	97	5	opposite	opposite	ADJ
ap-917	97	6	effects	effect	NOUN
ap-917	97	7	.	.	PUNCT
ap-917	98	1	thus	thus	ADV
ap-917	98	2	it	it	PRON
ap-917	98	3	can	can	AUX
ap-917	98	4	be	be	AUX
ap-917	98	5	concluded	conclude	VERB
ap-917	98	6	that	that	SCONJ
ap-917	98	7	increased	increase	VERB
ap-917	98	8	ncx	ncx	ADP
ap-917	98	9	activity	activity	NOUN
ap-917	98	10	(	(	PUNCT
ap-917	98	11	the	the	DET
ap-917	98	12	forward	forward	ADJ
ap-917	98	13	mode	mode	NOUN
ap-917	98	14	)	)	PUNCT
ap-917	98	15	alone	alone	ADV
ap-917	98	16	decreases	decrease	VERB
ap-917	98	17	the	the	DET
ap-917	98	18	force	force	NOUN
ap-917	98	19	(	(	PUNCT
ap-917	98	20	negative	negative	ADJ
ap-917	98	21	inotropic	inotropic	ADJ
ap-917	98	22	effect	effect	NOUN
ap-917	98	23	)	)	PUNCT
ap-917	98	24	and	and	CCONJ
ap-917	98	25	improves	improve	VERB
ap-917	98	26	relaxation	relaxation	NOUN
ap-917	98	27	(	(	PUNCT
ap-917	98	28	positive	positive	ADJ
ap-917	98	29	lusitropic	lusitropic	NOUN
ap-917	98	30	effect	effect	NOUN
ap-917	98	31	)	)	PUNCT
ap-917	98	32	,	,	PUNCT
ap-917	98	33	and	and	CCONJ
ap-917	98	34	vice	vice	ADV
ap-917	98	35	versa	versa	ADV
ap-917	98	36	.	.	PUNCT
ap-917	99	1	the	the	DET
ap-917	99	2	kinetics	kinetic	NOUN
ap-917	99	3	of	of	ADP
ap-917	99	4	an	an	DET
ap-917	99	5	acto	acto	PROPN
ap-917	99	6	-	-	PUNCT
ap-917	99	7	myosin	myosin	NOUN
ap-917	99	8	strong	strong	ADJ
ap-917	99	9	interaction	interaction	NOUN
ap-917	99	10	(	(	PUNCT
ap-917	99	11	am(t	am(t	NOUN
ap-917	99	12	)	)	PUNCT
ap-917	99	13	)	)	PUNCT
ap-917	99	14	represents	represent	VERB
ap-917	99	15	the	the	DET
ap-917	99	16	mechanical	mechanical	ADJ
ap-917	99	17	performance	performance	NOUN
ap-917	99	18	of	of	ADP
ap-917	99	19	virtual	virtual	ADJ
ap-917	99	20	cardiac	cardiac	ADJ
ap-917	99	21	myocyte	myocyte	NOUN
ap-917	99	22	.	.	PUNCT
ap-917	100	1	this	this	PRON
ap-917	100	2	is	be	AUX
ap-917	100	3	obtained	obtain	VERB
ap-917	100	4	from	from	ADP
ap-917	100	5	the	the	DET
ap-917	100	6	model	model	NOUN
ap-917	100	7	simulation	simulation	NOUN
ap-917	100	8	(	(	PUNCT
ap-917	100	9	contraction	contraction	NOUN
ap-917	100	10	subunit	subunit	NOUN
ap-917	100	11	)	)	PUNCT
ap-917	100	12	.	.	PUNCT
ap-917	101	1	the	the	DET
ap-917	101	2	original	original	ADJ
ap-917	101	3	description	description	NOUN
ap-917	101	4	was	be	AUX
ap-917	101	5	given	give	VERB
ap-917	101	6	in	in	ADP
ap-917	101	7	[	[	X
ap-917	101	8	6	6	NUM
ap-917	101	9	]	]	PUNCT
ap-917	101	10	.	.	PUNCT
ap-917	102	1	the	the	DET
ap-917	102	2	effect	effect	NOUN
ap-917	102	3	of	of	ADP
ap-917	102	4	heart	heart	NOUN
ap-917	102	5	rate	rate	VERB
ap-917	102	6	the	the	DET
ap-917	102	7	effect	effect	NOUN
ap-917	102	8	of	of	ADP
ap-917	102	9	ncx	ncx	NOUN
ap-917	102	10	during	during	ADP
ap-917	102	11	each	each	DET
ap-917	102	12	cardiac	cardiac	ADJ
ap-917	102	13	cycle	cycle	NOUN
ap-917	102	14	is	be	AUX
ap-917	102	15	time	time	NOUN
ap-917	102	16	-	-	PUNCT
ap-917	102	17	limited	limited	ADJ
ap-917	102	18	,	,	PUNCT
ap-917	102	19	and	and	CCONJ
ap-917	102	20	is	be	AUX
ap-917	102	21	therefore	therefore	ADV
ap-917	102	22	directly	directly	ADV
ap-917	102	23	influenced	influence	VERB
ap-917	102	24	by	by	ADP
ap-917	102	25	heart	heart	NOUN
ap-917	102	26	frequency	frequency	NOUN
ap-917	102	27	.	.	PUNCT
ap-917	103	1	shortening	shorten	VERB
ap-917	103	2	the	the	DET
ap-917	103	3	cardiac	cardiac	ADJ
ap-917	103	4	period	period	NOUN
ap-917	103	5	means	mean	VERB
ap-917	103	6	that	that	SCONJ
ap-917	103	7	less	less	ADJ
ap-917	103	8	time	time	NOUN
ap-917	103	9	is	be	AUX
ap-917	103	10	available	available	ADJ
ap-917	103	11	for	for	ADP
ap-917	103	12	ca2	ca2	PROPN
ap-917	103	13	�	�	PROPN
ap-917	103	14	removal	removal	NOUN
ap-917	103	15	by	by	ADP
ap-917	103	16	ncx	ncx	PROPN
ap-917	103	17	(	(	PUNCT
ap-917	103	18	fig	fig	NOUN
ap-917	103	19	.	.	PUNCT
ap-917	104	1	8)	8)	NUM
ap-917	104	2	.	.	PUNCT
ap-917	105	1	if	if	SCONJ
ap-917	105	2	ncx	ncx	ADJ
ap-917	105	3	activity	activity	NOUN
ap-917	105	4	is	be	AUX
ap-917	105	5	decreased	decrease	VERB
ap-917	105	6	,	,	PUNCT
ap-917	105	7	at	at	ADP
ap-917	105	8	higher	high	ADJ
ap-917	105	9	rates	rate	NOUN
ap-917	105	10	(	(	PUNCT
ap-917	105	11	2–3	2–3	NUM
ap-917	105	12	hz	hz	NOUN
ap-917	105	13	)	)	PUNCT
ap-917	105	14	ca2	ca2	PROPN
ap-917	105	15	�	�	PROPN
ap-917	105	16	does	do	AUX
ap-917	105	17	not	not	PART
ap-917	105	18	return	return	VERB
ap-917	105	19	to	to	ADP
ap-917	105	20	6	6	NUM
ap-917	105	21	©	©	PROPN
ap-917	105	22	czech	czech	PROPN
ap-917	105	23	technical	technical	PROPN
ap-917	105	24	university	university	PROPN
ap-917	105	25	publishing	publishing	NOUN
ap-917	105	26	house	house	NOUN
ap-917	105	27	http://ctn.cvut.cz/ap/	http://ctn.cvut.cz/ap/	PROPN
ap-917	105	28	acta	acta	PROPN
ap-917	105	29	polytechnica	polytechnica	PROPN
ap-917	105	30	vol	vol	NOUN
ap-917	105	31	.	.	PUNCT
ap-917	106	1	48	48	NUM
ap-917	106	2	no	no	NOUN
ap-917	106	3	.	.	PROPN
ap-917	107	1	1/2008	1/2008	NUM
ap-917	107	2	am	am	NOUN
ap-917	107	3	,	,	PUNCT
ap-917	107	4	3	3	NUM
ap-917	107	5	hz	hz	VERB
ap-917	107	6	0	0	NUM
ap-917	107	7	00e+00	00e+00	NUM
ap-917	107	8	.	.	PUNCT
ap-917	107	9	5	5	NUM
ap-917	107	10	00e-09	00e-09	NOUN
ap-917	107	11	.	.	PUNCT
ap-917	108	1	1	1	NUM
ap-917	108	2	00e-08	00e-08	NOUN
ap-917	108	3	.	.	PUNCT
ap-917	109	1	1	1	NUM
ap-917	109	2	50e-08	50e-08	NUM
ap-917	109	3	.	.	PUNCT
ap-917	109	4	2	2	NUM
ap-917	109	5	00e-08	00e-08	NOUN
ap-917	109	6	.	.	PUNCT
ap-917	110	1	2.50e-08	2.50e-08	NUM
ap-917	110	2	299	299	NUM
ap-917	110	3	00	00	NUM
ap-917	110	4	.	.	PUNCT
ap-917	111	1	299	299	NUM
ap-917	111	2	25	25	NUM
ap-917	111	3	.	.	PUNCT
ap-917	112	1	299	299	NUM
ap-917	112	2	50	50	NUM
ap-917	112	3	.	.	PUNCT
ap-917	113	1	299	299	NUM
ap-917	113	2	75	75	NUM
ap-917	113	3	.	.	PUNCT
ap-917	114	1	300	300	NUM
ap-917	114	2	00	00	NUM
ap-917	114	3	.	.	PUNCT
ap-917	115	1	time	time	NOUN
ap-917	115	2	(	(	PUNCT
ap-917	115	3	s	s	X
ap-917	115	4	)	)	PUNCT
ap-917	115	5	a	a	DET
ap-917	115	6	m	m	PROPN
ap-917	115	7	(	(	PUNCT
ap-917	115	8	m	m	PROPN
ap-917	115	9	o	o	NOUN
ap-917	115	10	l	l	NOUN
ap-917	115	11	)	)	PUNCT
ap-917	115	12	norm	norm	NOUN
ap-917	115	13	no	no	DET
ap-917	115	14	ncx	ncx	ADJ
ap-917	115	15	fig	fig	NOUN
ap-917	115	16	.	.	PUNCT
ap-917	116	1	6	6	NUM
ap-917	116	2	:	:	PUNCT
ap-917	116	3	contractile	contractile	NOUN
ap-917	116	4	force	force	NOUN
ap-917	116	5	in	in	ADP
ap-917	116	6	nf	nf	ADJ
ap-917	116	7	heart	heart	NOUN
ap-917	116	8	and	and	CCONJ
ap-917	116	9	in	in	ADP
ap-917	116	10	heart	heart	NOUN
ap-917	116	11	with	with	ADP
ap-917	116	12	turned	turn	VERB
ap-917	116	13	ncx	ncx	ADP
ap-917	116	14	off	off	ADP
ap-917	116	15	,	,	PUNCT
ap-917	116	16	at	at	ADP
ap-917	116	17	3	3	NUM
ap-917	116	18	hz	hz	VERB
ap-917	116	19	ca	ca	NOUN
ap-917	116	20	fluxes	flux	NOUN
ap-917	116	21	at	at	ADP
ap-917	116	22	1	1	NUM
ap-917	116	23	hz	hz	VERB
ap-917	116	24	,	,	PUNCT
ap-917	116	25	normal	normal	ADJ
ap-917	116	26	cells	cell	NOUN
ap-917	116	27	0	0	NUM
ap-917	116	28	00e+00	00e+00	NOUN
ap-917	116	29	.	.	PUNCT
ap-917	116	30	4	4	NUM
ap-917	116	31	00e-03	00e-03	NUM
ap-917	116	32	.	.	PUNCT
ap-917	117	1	8	8	NUM
ap-917	117	2	00e-03	00e-03	NUM
ap-917	117	3	.	.	PUNCT
ap-917	118	1	1.20e-02	1.20e-02	NUM
ap-917	118	2	1.60e-02	1.60e-02	NUM
ap-917	118	3	qie	qie	VERB
ap-917	118	4	qin	qin	PROPN
ap-917	118	5	q	q	X
ap-917	118	6	ncx	ncx	ADP
ap-917	118	7	c	c	PROPN
ap-917	118	8	a	a	DET
ap-917	118	9	fl	fl	NUM
ap-917	118	10	u	u	NOUN
ap-917	118	11	x	x	X
ap-917	118	12	e	e	X
ap-917	118	13	s	s	X
ap-917	118	14	(	(	PUNCT
ap-917	118	15	m	m	PROPN
ap-917	118	16	o	o	NOUN
ap-917	118	17	l	l	NOUN
ap-917	118	18	)	)	PUNCT
ap-917	118	19	fig	fig	NOUN
ap-917	118	20	.	.	PUNCT
ap-917	119	1	7	7	NUM
ap-917	119	2	:	:	SYM
ap-917	119	3	total	total	ADJ
ap-917	119	4	ca2	ca2	PROPN
ap-917	119	5	�	�	PROPN
ap-917	119	6	fluxes	flux	NOUN
ap-917	119	7	(	(	PUNCT
ap-917	119	8	per	per	ADP
ap-917	119	9	1	1	NUM
ap-917	119	10	sec	sec	PROPN
ap-917	119	11	)	)	PUNCT
ap-917	119	12	at	at	ADP
ap-917	119	13	1	1	NUM
ap-917	119	14	hz	hz	VERB
ap-917	119	15	,	,	PUNCT
ap-917	119	16	nf	nf	VERB
ap-917	119	17	the	the	DET
ap-917	119	18	baseline	baseline	NOUN
ap-917	119	19	,	,	PUNCT
ap-917	119	20	and	and	CCONJ
ap-917	119	21	therefore	therefore	ADV
ap-917	119	22	the	the	DET
ap-917	119	23	myocardium	myocardium	NOUN
ap-917	119	24	may	may	AUX
ap-917	119	25	not	not	PART
ap-917	119	26	relax	relax	VERB
ap-917	119	27	properly	properly	ADV
ap-917	119	28	between	between	ADP
ap-917	119	29	beats	beat	NOUN
ap-917	119	30	(	(	PUNCT
ap-917	119	31	fig	fig	NOUN
ap-917	119	32	.	.	PUNCT
ap-917	120	1	6	6	NUM
ap-917	120	2	)	)	PUNCT
ap-917	120	3	.	.	PUNCT
ap-917	121	1	3.2	3.2	NUM
ap-917	121	2	ncx	ncx	NOUN
ap-917	121	3	in	in	ADP
ap-917	121	4	serca	serca	NOUN
ap-917	121	5	dysfunction	dysfunction	NOUN
ap-917	121	6	impaired	impair	VERB
ap-917	121	7	calcium	calcium	NOUN
ap-917	121	8	handling	handling	NOUN
ap-917	121	9	in	in	ADP
ap-917	121	10	chronic	chronic	ADJ
ap-917	121	11	heart	heart	NOUN
ap-917	121	12	failure	failure	NOUN
ap-917	121	13	(	(	PUNCT
ap-917	121	14	f	f	X
ap-917	121	15	)	)	PUNCT
ap-917	121	16	was	be	AUX
ap-917	121	17	simulated	simulate	VERB
ap-917	121	18	by	by	ADP
ap-917	121	19	decreasing	decrease	VERB
ap-917	121	20	the	the	DET
ap-917	121	21	serca	serca	NOUN
ap-917	121	22	activity	activity	NOUN
ap-917	121	23	to	to	ADP
ap-917	121	24	50	50	NUM
ap-917	121	25	%	%	NOUN
ap-917	121	26	of	of	ADP
ap-917	121	27	the	the	DET
ap-917	121	28	norm	norm	NOUN
ap-917	121	29	.	.	PUNCT
ap-917	122	1	the	the	DET
ap-917	122	2	activity	activity	NOUN
ap-917	122	3	of	of	ADP
ap-917	122	4	ncx	ncx	NOUN
ap-917	122	5	was	be	AUX
ap-917	122	6	varied	varied	ADJ
ap-917	122	7	between	between	ADP
ap-917	122	8	0	0	NUM
ap-917	122	9	,	,	PUNCT
ap-917	122	10	100	100	NUM
ap-917	122	11	and	and	CCONJ
ap-917	122	12	150	150	NUM
ap-917	122	13	%	%	NOUN
ap-917	122	14	.	.	PUNCT
ap-917	123	1	decreased	decrease	VERB
ap-917	123	2	serca	serca	NOUN
ap-917	123	3	activity	activity	NOUN
ap-917	123	4	alone	alone	ADV
ap-917	123	5	resulted	result	VERB
ap-917	123	6	in	in	ADP
ap-917	123	7	lower	low	ADJ
ap-917	123	8	calcium	calcium	NOUN
ap-917	123	9	peak	peak	NOUN
ap-917	123	10	and	and	CCONJ
ap-917	123	11	force	force	NOUN
ap-917	123	12	transient	transient	NOUN
ap-917	123	13	(	(	PUNCT
ap-917	123	14	by	by	ADP
ap-917	123	15	cca	cca	PROPN
ap-917	123	16	40	40	NUM
ap-917	123	17	%	%	NOUN
ap-917	123	18	)	)	PUNCT
ap-917	123	19	and	and	CCONJ
ap-917	123	20	increased	increase	VERB
ap-917	123	21	calcium	calcium	NOUN
ap-917	123	22	during	during	ADP
ap-917	123	23	the	the	DET
ap-917	123	24	relaxation	relaxation	NOUN
ap-917	123	25	phase	phase	NOUN
ap-917	123	26	(	(	PUNCT
ap-917	123	27	compared	compare	VERB
ap-917	123	28	to	to	ADP
ap-917	123	29	the	the	DET
ap-917	123	30	non	non	ADJ
ap-917	123	31	-	-	ADJ
ap-917	123	32	failing	failing	ADJ
ap-917	123	33	model	model	NOUN
ap-917	123	34	)	)	PUNCT
ap-917	123	35	.	.	PUNCT
ap-917	124	1	this	this	PRON
ap-917	124	2	is	be	AUX
ap-917	124	3	consistent	consistent	ADJ
ap-917	124	4	with	with	ADP
ap-917	124	5	many	many	ADJ
ap-917	124	6	experimental	experimental	ADJ
ap-917	124	7	findings	finding	NOUN
ap-917	124	8	[	[	X
ap-917	124	9	11	11	NUM
ap-917	124	10	,	,	PUNCT
ap-917	124	11	12	12	NUM
ap-917	124	12	]	]	PUNCT
ap-917	124	13	.	.	PUNCT
ap-917	125	1	by	by	ADP
ap-917	125	2	increasing	increase	VERB
ap-917	125	3	the	the	DET
ap-917	125	4	activity	activity	NOUN
ap-917	125	5	of	of	ADP
ap-917	125	6	ncx	ncx	NOUN
ap-917	125	7	to	to	PART
ap-917	125	8	150	150	NUM
ap-917	125	9	%	%	NOUN
ap-917	125	10	of	of	ADP
ap-917	125	11	n	n	CCONJ
ap-917	125	12	,	,	PUNCT
ap-917	125	13	the	the	DET
ap-917	125	14	relaxation	relaxation	NOUN
ap-917	125	15	(	(	PUNCT
ap-917	125	16	force	force	NOUN
ap-917	125	17	and	and	CCONJ
ap-917	125	18	ca2	ca2	PROPN
ap-917	125	19	�	�	PROPN
ap-917	125	20	)	)	PUNCT
ap-917	125	21	was	be	AUX
ap-917	125	22	restored	restore	VERB
ap-917	125	23	.	.	PUNCT
ap-917	126	1	however	however	ADV
ap-917	126	2	,	,	PUNCT
ap-917	126	3	this	this	PRON
ap-917	126	4	is	be	AUX
ap-917	126	5	at	at	ADP
ap-917	126	6	the	the	DET
ap-917	126	7	cost	cost	NOUN
ap-917	126	8	of	of	ADP
ap-917	126	9	a	a	DET
ap-917	126	10	further	further	ADJ
ap-917	126	11	decline	decline	NOUN
ap-917	126	12	of	of	ADP
ap-917	126	13	the	the	DET
ap-917	126	14	maximal	maximal	ADJ
ap-917	126	15	force	force	NOUN
ap-917	126	16	(	(	PUNCT
ap-917	126	17	to	to	ADP
ap-917	126	18	50	50	NUM
ap-917	126	19	%	%	NOUN
ap-917	126	20	)	)	PUNCT
ap-917	126	21	(	(	PUNCT
ap-917	126	22	fig	fig	NOUN
ap-917	126	23	.	.	PUNCT
ap-917	127	1	9	9	NUM
ap-917	127	2	)	)	PUNCT
ap-917	127	3	.	.	PUNCT
ap-917	128	1	importantly	importantly	ADV
ap-917	128	2	,	,	PUNCT
ap-917	128	3	this	this	DET
ap-917	128	4	effect	effect	NOUN
ap-917	128	5	was	be	AUX
ap-917	128	6	pronounced	pronounce	VERB
ap-917	128	7	at	at	ADP
ap-917	128	8	high	high	ADJ
ap-917	128	9	frequencies	frequency	NOUN
ap-917	128	10	(	(	PUNCT
ap-917	128	11	3hz	3hz	ADJ
ap-917	128	12	–	–	PUNCT
ap-917	128	13	fig	fig	NOUN
ap-917	128	14	.	.	PUNCT
ap-917	129	1	10	10	NUM
ap-917	129	2	)	)	PUNCT
ap-917	129	3	.	.	PUNCT
ap-917	130	1	4	4	NUM
ap-917	130	2	discussion	discussion	NOUN
ap-917	130	3	the	the	DET
ap-917	130	4	role	role	NOUN
ap-917	130	5	of	of	ADP
ap-917	130	6	ncx	ncx	NOUN
ap-917	130	7	in	in	ADP
ap-917	130	8	ecc	ecc	PROPN
ap-917	130	9	is	be	AUX
ap-917	130	10	quite	quite	ADV
ap-917	130	11	complex	complex	ADJ
ap-917	130	12	.	.	PUNCT
ap-917	131	1	at	at	ADP
ap-917	131	2	first	first	ADV
ap-917	131	3	,	,	PUNCT
ap-917	131	4	by	by	ADP
ap-917	131	5	removing	remove	VERB
ap-917	131	6	calcium	calcium	NOUN
ap-917	131	7	from	from	ADP
ap-917	131	8	the	the	DET
ap-917	131	9	cell	cell	NOUN
ap-917	131	10	,	,	PUNCT
ap-917	131	11	increased	increase	VERB
ap-917	131	12	ncx	ncx	ADV
ap-917	131	13	reduces	reduce	VERB
ap-917	131	14	©	©	PROPN
ap-917	131	15	czech	czech	PROPN
ap-917	131	16	technical	technical	PROPN
ap-917	131	17	university	university	PROPN
ap-917	131	18	publishing	publishing	NOUN
ap-917	131	19	house	house	NOUN
ap-917	131	20	http://ctn.cvut.cz/ap/	http://ctn.cvut.cz/ap/	PROPN
ap-917	131	21	7	7	NUM
ap-917	131	22	acta	acta	PROPN
ap-917	131	23	polytechnica	polytechnica	PROPN
ap-917	131	24	vol	vol	NOUN
ap-917	131	25	.	.	PUNCT
ap-917	132	1	48	48	NUM
ap-917	132	2	no	no	NOUN
ap-917	132	3	.	.	PUNCT
ap-917	133	1	1/2008	1/2008	NUM
ap-917	133	2	q	q	NOUN
ap-917	133	3	ncx	ncx	NOUN
ap-917	133	4	(	(	PUNCT
ap-917	133	5	norm	norm	NOUN
ap-917	133	6	)	)	PUNCT
ap-917	133	7	0.00e+00	0.00e+00	NUM
ap-917	134	1	2.10e-03	2.10e-03	NUM
ap-917	134	2	1	1	NUM
ap-917	134	3	hz	hz	VERB
ap-917	134	4	2	2	NUM
ap-917	134	5	hz	hz	VERB
ap-917	134	6	3	3	NUM
ap-917	134	7	hz	hz	VERB
ap-917	134	8	q	q	PROPN
ap-917	134	9	n	n	NOUN
ap-917	134	10	c	c	NOUN
ap-917	134	11	x	x	SYM
ap-917	134	12	(	(	PUNCT
ap-917	134	13	m	m	VERB
ap-917	134	14	o	o	NOUN
ap-917	134	15	l/	l/	X
ap-917	134	16	s	s	PART
ap-917	134	17	)	)	PUNCT
ap-917	134	18	fig	fig	NOUN
ap-917	134	19	.	.	PUNCT
ap-917	135	1	8	8	NUM
ap-917	135	2	:	:	PUNCT
ap-917	135	3	total	total	ADJ
ap-917	135	4	ca2	ca2	PROPN
ap-917	135	5	�	�	PROPN
ap-917	135	6	fluxes	flux	NOUN
ap-917	135	7	(	(	PUNCT
ap-917	135	8	per	per	ADP
ap-917	135	9	1	1	NUM
ap-917	135	10	sec	sec	PROPN
ap-917	135	11	)	)	PUNCT
ap-917	135	12	at	at	ADP
ap-917	135	13	1	1	NUM
ap-917	135	14	,	,	PUNCT
ap-917	135	15	2	2	NUM
ap-917	135	16	and	and	CCONJ
ap-917	135	17	3	3	NUM
ap-917	135	18	hz	hz	VERB
ap-917	135	19	,	,	PUNCT
ap-917	135	20	nf	nf	X
ap-917	135	21	cai	cai	X
ap-917	135	22	(	(	PUNCT
ap-917	135	23	in	in	ADP
ap-917	135	24	nf	nf	NOUN
ap-917	135	25	and	and	CCONJ
ap-917	135	26	f	f	X
ap-917	135	27	)	)	PUNCT
ap-917	135	28	0	0	NUM
ap-917	135	29	00e+00	00e+00	NUM
ap-917	135	30	.	.	PUNCT
ap-917	136	1	2.10e-03	2.10e-03	NUM
ap-917	136	2	299	299	NUM
ap-917	136	3	00	00	NUM
ap-917	136	4	.	.	PUNCT
ap-917	137	1	299	299	NUM
ap-917	137	2	25	25	NUM
ap-917	137	3	.	.	PUNCT
ap-917	138	1	299	299	NUM
ap-917	138	2	50	50	NUM
ap-917	138	3	.	.	PUNCT
ap-917	139	1	299	299	NUM
ap-917	139	2	75	75	NUM
ap-917	139	3	.	.	PUNCT
ap-917	140	1	300	300	NUM
ap-917	140	2	00	00	NUM
ap-917	140	3	.	.	PUNCT
ap-917	141	1	time	time	NOUN
ap-917	141	2	(	(	PUNCT
ap-917	141	3	s	s	X
ap-917	141	4	)	)	PUNCT
ap-917	141	5	c	c	NOUN
ap-917	141	6	a	a	DET
ap-917	141	7	i	i	NOUN
ap-917	141	8	(	(	PUNCT
ap-917	141	9	m	m	PROPN
ap-917	141	10	o	o	NOUN
ap-917	141	11	l	l	NOUN
ap-917	141	12	)	)	PUNCT
ap-917	141	13	norm	norm	NOUN
ap-917	141	14	f	f	X
ap-917	141	15	,	,	PUNCT
ap-917	141	16	ncx	ncx	ADV
ap-917	141	17	100	100	NUM
ap-917	141	18	f	f	NOUN
ap-917	141	19	,	,	PUNCT
ap-917	141	20	ncx	ncx	ADP
ap-917	141	21	150	150	NUM
ap-917	141	22	fig	fig	NOUN
ap-917	141	23	.	.	PUNCT
ap-917	142	1	9	9	NUM
ap-917	142	2	:	:	PUNCT
ap-917	142	3	intracellular	intracellular	ADJ
ap-917	142	4	ca2	ca2	PROPN
ap-917	142	5	�	�	PROPN
ap-917	142	6	concentration	concentration	NOUN
ap-917	142	7	in	in	ADP
ap-917	142	8	nf	nf	NOUN
ap-917	142	9	and	and	CCONJ
ap-917	142	10	f	f	PROPN
ap-917	142	11	heart	heart	NOUN
ap-917	142	12	(	(	PUNCT
ap-917	142	13	serca	serca	NOUN
ap-917	142	14	activity	activity	NOUN
ap-917	142	15	50	50	NUM
ap-917	142	16	%	%	NOUN
ap-917	142	17	,	,	PUNCT
ap-917	142	18	ncx	ncx	ADP
ap-917	142	19	activity	activity	NOUN
ap-917	142	20	100	100	NUM
ap-917	142	21	%	%	NOUN
ap-917	142	22	and	and	CCONJ
ap-917	142	23	150	150	NUM
ap-917	142	24	%	%	NOUN
ap-917	142	25	)	)	PUNCT
ap-917	142	26	,	,	PUNCT
ap-917	142	27	at	at	ADP
ap-917	142	28	1	1	NUM
ap-917	142	29	hz	hz	VERB
ap-917	142	30	contractility	contractility	NOUN
ap-917	142	31	and	and	CCONJ
ap-917	142	32	thus	thus	ADV
ap-917	142	33	could	could	AUX
ap-917	142	34	have	have	VERB
ap-917	142	35	a	a	DET
ap-917	142	36	negative	negative	ADJ
ap-917	142	37	effect	effect	NOUN
ap-917	142	38	on	on	ADP
ap-917	142	39	cardiac	cardiac	ADJ
ap-917	142	40	performance	performance	NOUN
ap-917	142	41	.	.	PUNCT
ap-917	143	1	this	this	PRON
ap-917	143	2	is	be	AUX
ap-917	143	3	in	in	ADP
ap-917	143	4	line	line	NOUN
ap-917	143	5	with	with	ADP
ap-917	143	6	some	some	DET
ap-917	143	7	experimental	experimental	ADJ
ap-917	143	8	findings	finding	NOUN
ap-917	143	9	[	[	X
ap-917	143	10	13	13	NUM
ap-917	143	11	]	]	PUNCT
ap-917	143	12	.	.	PUNCT
ap-917	144	1	though	though	SCONJ
ap-917	144	2	the	the	DET
ap-917	144	3	transporting	transporting	ADJ
ap-917	144	4	capacity	capacity	NOUN
ap-917	144	5	of	of	ADP
ap-917	144	6	ncx	ncx	NOUN
ap-917	144	7	is	be	AUX
ap-917	144	8	much	much	ADV
ap-917	144	9	lower	low	ADJ
ap-917	144	10	than	than	ADP
ap-917	144	11	that	that	PRON
ap-917	144	12	of	of	ADP
ap-917	144	13	other	other	ADJ
ap-917	144	14	mechanisms	mechanism	NOUN
ap-917	144	15	(	(	PUNCT
ap-917	144	16	serca	serca	PROPN
ap-917	144	17	)	)	PUNCT
ap-917	144	18	,	,	PUNCT
ap-917	144	19	nxc	nxc	NOUN
ap-917	144	20	can	can	AUX
ap-917	144	21	influence	influence	VERB
ap-917	144	22	the	the	DET
ap-917	144	23	gradual	gradual	ADJ
ap-917	144	24	loading	loading	NOUN
ap-917	144	25	/	/	SYM
ap-917	144	26	unloading	unloading	NOUN
ap-917	144	27	of	of	ADP
ap-917	144	28	cellular	cellular	ADJ
ap-917	144	29	calcium	calcium	NOUN
ap-917	144	30	stores	store	NOUN
ap-917	144	31	.	.	PUNCT
ap-917	145	1	cellular	cellular	ADJ
ap-917	145	2	calcium	calcium	NOUN
ap-917	145	3	determines	determine	VERB
ap-917	145	4	the	the	DET
ap-917	145	5	maximal	maximal	ADJ
ap-917	145	6	contraction	contraction	NOUN
ap-917	145	7	force	force	NOUN
ap-917	145	8	.	.	PUNCT
ap-917	146	1	secondly	secondly	ADV
ap-917	146	2	,	,	PUNCT
ap-917	146	3	lowering	lower	VERB
ap-917	146	4	cellular	cellular	ADJ
ap-917	146	5	calcium	calcium	NOUN
ap-917	146	6	(	(	PUNCT
ap-917	146	7	both	both	CCONJ
ap-917	146	8	in	in	ADP
ap-917	146	9	stores	store	NOUN
ap-917	146	10	and	and	CCONJ
ap-917	146	11	free	free	PROPN
ap-917	146	12	ca2	ca2	PROPN
ap-917	146	13	�	�	PROPN
ap-917	146	14	)	)	PUNCT
ap-917	146	15	has	have	VERB
ap-917	146	16	a	a	DET
ap-917	146	17	direct	direct	ADJ
ap-917	146	18	positive	positive	ADJ
ap-917	146	19	effect	effect	NOUN
ap-917	146	20	on	on	ADP
ap-917	146	21	cardiac	cardiac	ADJ
ap-917	146	22	relaxation	relaxation	NOUN
ap-917	146	23	and	and	CCONJ
ap-917	146	24	so	so	ADV
ap-917	146	25	can	can	AUX
ap-917	146	26	improve	improve	VERB
ap-917	146	27	heart	heart	NOUN
ap-917	146	28	performance	performance	NOUN
ap-917	146	29	–	–	PUNCT
ap-917	146	30	the	the	DET
ap-917	146	31	heart	heart	NOUN
ap-917	146	32	is	be	AUX
ap-917	146	33	a	a	DET
ap-917	146	34	pulsation	pulsation	NOUN
ap-917	146	35	pump	pump	NOUN
ap-917	146	36	so	so	SCONJ
ap-917	146	37	the	the	DET
ap-917	146	38	relaxation	relaxation	NOUN
ap-917	146	39	is	be	AUX
ap-917	146	40	as	as	ADV
ap-917	146	41	necessary	necessary	ADJ
ap-917	146	42	as	as	SCONJ
ap-917	146	43	the	the	DET
ap-917	146	44	contraction	contraction	NOUN
ap-917	146	45	and	and	CCONJ
ap-917	146	46	both	both	PRON
ap-917	146	47	need	need	VERB
ap-917	146	48	to	to	PART
ap-917	146	49	alternate	alternate	VERB
ap-917	146	50	periodically	periodically	ADV
ap-917	146	51	.	.	PUNCT
ap-917	147	1	moreover	moreover	ADV
ap-917	147	2	,	,	PUNCT
ap-917	147	3	the	the	DET
ap-917	147	4	nutrition	nutrition	NOUN
ap-917	147	5	(	(	PUNCT
ap-917	147	6	blood	blood	NOUN
ap-917	147	7	supply	supply	NOUN
ap-917	147	8	)	)	PUNCT
ap-917	147	9	of	of	ADP
ap-917	147	10	the	the	DET
ap-917	147	11	heart	heart	NOUN
ap-917	147	12	is	be	AUX
ap-917	147	13	better	well	ADJ
ap-917	147	14	during	during	ADP
ap-917	147	15	the	the	DET
ap-917	147	16	relaxation	relaxation	NOUN
ap-917	147	17	phase	phase	NOUN
ap-917	147	18	(	(	PUNCT
ap-917	147	19	it	it	PRON
ap-917	147	20	almost	almost	ADV
ap-917	147	21	stops	stop	VERB
ap-917	147	22	during	during	ADP
ap-917	147	23	peak	peak	NOUN
ap-917	147	24	contraction	contraction	NOUN
ap-917	147	25	)	)	PUNCT
ap-917	147	26	.	.	PUNCT
ap-917	148	1	thus	thus	ADV
ap-917	148	2	it	it	PRON
ap-917	148	3	can	can	AUX
ap-917	148	4	not	not	PART
ap-917	148	5	be	be	AUX
ap-917	148	6	simply	simply	ADV
ap-917	148	7	concluded	conclude	VERB
ap-917	148	8	which	which	PRON
ap-917	148	9	of	of	ADP
ap-917	148	10	the	the	DET
ap-917	148	11	two	two	NUM
ap-917	148	12	effects	effect	NOUN
ap-917	148	13	should	should	AUX
ap-917	148	14	take	take	VERB
ap-917	148	15	precedence	precedence	NOUN
ap-917	148	16	.	.	PUNCT
ap-917	149	1	nor	nor	CCONJ
ap-917	149	2	can	can	AUX
ap-917	149	3	we	we	PRON
ap-917	149	4	calculate	calculate	VERB
ap-917	149	5	the	the	DET
ap-917	149	6	amplitude	amplitude	NOUN
ap-917	149	7	of	of	ADP
ap-917	149	8	force	force	NOUN
ap-917	149	9	(	(	PUNCT
ap-917	149	10	am	am	NOUN
ap-917	149	11	)	)	PUNCT
ap-917	149	12	oscillation	oscillation	NOUN
ap-917	149	13	as	as	ADP
ap-917	149	14	a	a	DET
ap-917	149	15	measure	measure	NOUN
ap-917	149	16	of	of	ADP
ap-917	149	17	performance	performance	NOUN
ap-917	149	18	.	.	PUNCT
ap-917	150	1	thirdly	thirdly	ADV
ap-917	150	2	,	,	PUNCT
ap-917	150	3	ncx	ncx	ADV
ap-917	150	4	is	be	AUX
ap-917	150	5	capable	capable	ADJ
ap-917	150	6	of	of	ADP
ap-917	150	7	“	"	PUNCT
ap-917	150	8	reverse	reverse	ADJ
ap-917	150	9	mode	mode	NOUN
ap-917	150	10	”	"	PUNCT
ap-917	150	11	operation	operation	NOUN
ap-917	150	12	,	,	PUNCT
ap-917	150	13	i.e.	i.e.	X
ap-917	150	14	it	it	PRON
ap-917	150	15	can	can	AUX
ap-917	150	16	load	load	VERB
ap-917	150	17	calcium	calcium	NOUN
ap-917	150	18	into	into	ADP
ap-917	150	19	the	the	DET
ap-917	150	20	cell	cell	NOUN
ap-917	150	21	during	during	ADP
ap-917	150	22	the	the	DET
ap-917	150	23	early	early	ADJ
ap-917	150	24	phase	phase	NOUN
ap-917	150	25	of	of	ADP
ap-917	150	26	the	the	DET
ap-917	150	27	cardiac	cardiac	ADJ
ap-917	150	28	cycle	cycle	NOUN
ap-917	150	29	.	.	PUNCT
ap-917	151	1	the	the	DET
ap-917	151	2	effect	effect	NOUN
ap-917	151	3	of	of	ADP
ap-917	151	4	ncx	ncx	NOUN
ap-917	151	5	is	be	AUX
ap-917	151	6	also	also	ADV
ap-917	151	7	heart	heart	NOUN
ap-917	151	8	-	-	PUNCT
ap-917	151	9	rate	rate	NOUN
ap-917	151	10	dependent	dependent	ADJ
ap-917	151	11	.	.	PUNCT
ap-917	152	1	at	at	ADP
ap-917	152	2	low	low	ADJ
ap-917	152	3	frequencies	frequency	NOUN
ap-917	152	4	(	(	PUNCT
ap-917	152	5	<	<	X
ap-917	152	6	~1hz	~1hz	X
ap-917	152	7	)	)	PUNCT
ap-917	152	8	,	,	PUNCT
ap-917	152	9	the	the	DET
ap-917	152	10	relatively	relatively	ADV
ap-917	152	11	long	long	ADJ
ap-917	152	12	period	period	NOUN
ap-917	152	13	offers	offer	VERB
ap-917	152	14	enough	enough	ADJ
ap-917	152	15	reserve	reserve	NOUN
ap-917	152	16	capacity	capacity	NOUN
ap-917	152	17	for	for	ADP
ap-917	152	18	extrusion	extrusion	NOUN
ap-917	152	19	of	of	ADP
ap-917	152	20	ca2	ca2	PROPN
ap-917	152	21	�	�	PROPN
ap-917	152	22	,	,	PUNCT
ap-917	152	23	which	which	PRON
ap-917	152	24	controls	control	VERB
ap-917	152	25	relaxation	relaxation	NOUN
ap-917	152	26	.	.	PUNCT
ap-917	153	1	the	the	DET
ap-917	153	2	extrusion	extrusion	NOUN
ap-917	153	3	(	(	PUNCT
ap-917	153	4	and	and	CCONJ
ap-917	153	5	therefore	therefore	ADV
ap-917	153	6	the	the	DET
ap-917	153	7	relaxation	relaxation	NOUN
ap-917	153	8	)	)	PUNCT
ap-917	153	9	takes	take	VERB
ap-917	153	10	longer	long	ADV
ap-917	153	11	,	,	PUNCT
ap-917	153	12	but	but	CCONJ
ap-917	153	13	ultimately	ultimately	ADV
ap-917	153	14	fully	fully	ADV
ap-917	153	15	completes	complete	VERB
ap-917	153	16	(	(	PUNCT
ap-917	153	17	figs	fig	NOUN
ap-917	153	18	.	.	PUNCT
ap-917	154	1	4	4	NUM
ap-917	154	2	,	,	PUNCT
ap-917	154	3	5	5	NUM
ap-917	154	4	)	)	PUNCT
ap-917	154	5	.	.	PUNCT
ap-917	155	1	at	at	ADP
ap-917	155	2	higher	high	ADJ
ap-917	155	3	rates	rate	NOUN
ap-917	155	4	full	full	ADJ
ap-917	155	5	relaxation	relaxation	NOUN
ap-917	155	6	is	be	AUX
ap-917	155	7	not	not	PART
ap-917	155	8	achieved	achieve	VERB
ap-917	155	9	.	.	PUNCT
ap-917	156	1	8	8	NUM
ap-917	157	1	©	©	PROPN
ap-917	157	2	czech	czech	PROPN
ap-917	157	3	technical	technical	PROPN
ap-917	157	4	university	university	PROPN
ap-917	157	5	publishing	publishing	NOUN
ap-917	157	6	house	house	NOUN
ap-917	157	7	http://ctn.cvut.cz/ap/	http://ctn.cvut.cz/ap/	PROPN
ap-917	157	8	acta	acta	PROPN
ap-917	157	9	polytechnica	polytechnica	PROPN
ap-917	157	10	vol	vol	NOUN
ap-917	157	11	.	.	PUNCT
ap-917	158	1	48	48	NUM
ap-917	158	2	no	no	NOUN
ap-917	158	3	.	.	PUNCT
ap-917	159	1	1/2008	1/2008	NUM
ap-917	159	2	am	am	NOUN
ap-917	159	3	/	/	SYM
ap-917	159	4	force	force	NOUN
ap-917	159	5	(	(	PUNCT
ap-917	159	6	in	in	ADP
ap-917	159	7	nf	nf	NOUN
ap-917	159	8	and	and	CCONJ
ap-917	159	9	f	f	X
ap-917	159	10	)	)	PUNCT
ap-917	159	11	,	,	PUNCT
ap-917	159	12	3	3	NUM
ap-917	159	13	hz	hz	VERB
ap-917	159	14	0	0	NUM
ap-917	159	15	00e+00	00e+00	NUM
ap-917	159	16	.	.	PUNCT
ap-917	159	17	2	2	NUM
ap-917	159	18	00e-09	00e-09	NOUN
ap-917	159	19	.	.	PUNCT
ap-917	160	1	4	4	NUM
ap-917	160	2	00e-09	00e-09	NOUN
ap-917	160	3	.	.	PUNCT
ap-917	161	1	6	6	NUM
ap-917	161	2	00e-09	00e-09	NOUN
ap-917	161	3	.	.	PUNCT
ap-917	162	1	8.00e-09	8.00e-09	NUM
ap-917	162	2	299	299	NUM
ap-917	162	3	00	00	NUM
ap-917	162	4	.	.	PUNCT
ap-917	163	1	299	299	NUM
ap-917	163	2	25	25	NUM
ap-917	163	3	.	.	PUNCT
ap-917	164	1	299	299	NUM
ap-917	164	2	50	50	NUM
ap-917	164	3	.	.	PUNCT
ap-917	165	1	299	299	NUM
ap-917	165	2	75	75	NUM
ap-917	165	3	.	.	PUNCT
ap-917	166	1	300	300	NUM
ap-917	166	2	00	00	NUM
ap-917	166	3	.	.	PUNCT
ap-917	167	1	time	time	NOUN
ap-917	167	2	(	(	PUNCT
ap-917	167	3	s	s	X
ap-917	167	4	)	)	PUNCT
ap-917	167	5	a	a	DET
ap-917	167	6	m	m	PROPN
ap-917	167	7	(	(	PUNCT
ap-917	167	8	m	m	PROPN
ap-917	167	9	o	o	NOUN
ap-917	167	10	l	l	NOUN
ap-917	167	11	)	)	PUNCT
ap-917	167	12	norm	norm	NOUN
ap-917	167	13	f	f	X
ap-917	167	14	,	,	PUNCT
ap-917	167	15	ncx	ncx	ADV
ap-917	167	16	100	100	NUM
ap-917	167	17	f	f	NOUN
ap-917	167	18	,	,	PUNCT
ap-917	167	19	ncx	ncx	ADP
ap-917	167	20	150	150	NUM
ap-917	167	21	fig	fig	NOUN
ap-917	167	22	.	.	PUNCT
ap-917	168	1	10	10	NUM
ap-917	168	2	:	:	PUNCT
ap-917	168	3	contractile	contractile	NOUN
ap-917	168	4	force	force	NOUN
ap-917	168	5	in	in	ADP
ap-917	168	6	nf	nf	NOUN
ap-917	168	7	and	and	CCONJ
ap-917	168	8	f	f	PROPN
ap-917	168	9	heart	heart	NOUN
ap-917	168	10	(	(	PUNCT
ap-917	168	11	serca	serca	NOUN
ap-917	168	12	activity	activity	NOUN
ap-917	168	13	50	50	NUM
ap-917	168	14	%	%	NOUN
ap-917	168	15	,	,	PUNCT
ap-917	168	16	ncx	ncx	ADP
ap-917	168	17	activity	activity	NOUN
ap-917	168	18	100	100	NUM
ap-917	168	19	%	%	NOUN
ap-917	168	20	and	and	CCONJ
ap-917	168	21	150	150	NUM
ap-917	168	22	%	%	NOUN
ap-917	168	23	)	)	PUNCT
ap-917	168	24	,	,	PUNCT
ap-917	168	25	at	at	ADP
ap-917	168	26	3	3	NUM
ap-917	168	27	hz	hz	VERB
ap-917	168	28	ca	ca	NOUN
ap-917	168	29	fluxes	flux	NOUN
ap-917	168	30	(	(	PUNCT
ap-917	168	31	per	per	ADP
ap-917	168	32	cycle	cycle	NOUN
ap-917	168	33	)	)	PUNCT
ap-917	168	34	,	,	PUNCT
ap-917	168	35	1	1	NUM
ap-917	168	36	hz	hz	VERB
ap-917	168	37	0	0	NUM
ap-917	168	38	00e+00	00e+00	NUM
ap-917	168	39	.	.	PUNCT
ap-917	168	40	4	4	NUM
ap-917	168	41	00e-03	00e-03	NUM
ap-917	168	42	.	.	PUNCT
ap-917	169	1	8	8	NUM
ap-917	169	2	00e-03	00e-03	NUM
ap-917	169	3	.	.	PUNCT
ap-917	170	1	1	1	NUM
ap-917	170	2	20e-02	20e-02	NUM
ap-917	170	3	.	.	PUNCT
ap-917	171	1	1.60e-02	1.60e-02	NUM
ap-917	171	2	qie	qie	PROPN
ap-917	171	3	qei	qei	NOUN
ap-917	171	4	qin	qin	PROPN
ap-917	171	5	qncx	qncx	PROPN
ap-917	171	6	q	q	PROPN
ap-917	172	1	(	(	PUNCT
ap-917	172	2	m	m	VERB
ap-917	172	3	o	o	NOUN
ap-917	172	4	l/	l/	X
ap-917	172	5	s	s	PART
ap-917	172	6	)	)	PUNCT
ap-917	172	7	norm	norm	NOUN
ap-917	172	8	f	f	X
ap-917	172	9	,	,	PUNCT
ap-917	172	10	ncx	ncx	ADV
ap-917	172	11	100	100	NUM
ap-917	172	12	f	f	NOUN
ap-917	172	13	,	,	PUNCT
ap-917	172	14	ncx	ncx	ADP
ap-917	172	15	150	150	NUM
ap-917	172	16	fig	fig	NOUN
ap-917	172	17	.	.	PUNCT
ap-917	173	1	11	11	NUM
ap-917	173	2	:	:	PUNCT
ap-917	173	3	total	total	ADJ
ap-917	173	4	ca2	ca2	PROPN
ap-917	173	5	�	�	PROPN
ap-917	173	6	fluxes	flux	NOUN
ap-917	173	7	(	(	PUNCT
ap-917	173	8	per	per	ADP
ap-917	173	9	1	1	NUM
ap-917	173	10	sec	sec	PROPN
ap-917	173	11	)	)	PUNCT
ap-917	173	12	in	in	ADP
ap-917	173	13	nf	nf	ADJ
ap-917	173	14	and	and	CCONJ
ap-917	173	15	f	f	PROPN
ap-917	173	16	heart	heart	NOUN
ap-917	173	17	(	(	PUNCT
ap-917	173	18	serca	serca	NOUN
ap-917	173	19	activity	activity	NOUN
ap-917	173	20	50	50	NUM
ap-917	173	21	%	%	NOUN
ap-917	173	22	,	,	PUNCT
ap-917	173	23	ncx	ncx	ADP
ap-917	173	24	activity	activity	NOUN
ap-917	173	25	100	100	NUM
ap-917	173	26	%	%	NOUN
ap-917	173	27	and	and	CCONJ
ap-917	173	28	150	150	NUM
ap-917	173	29	%	%	NOUN
ap-917	173	30	)	)	PUNCT
ap-917	173	31	,	,	PUNCT
ap-917	173	32	at	at	ADP
ap-917	173	33	1	1	NUM
ap-917	173	34	hz	hz	VERB
ap-917	173	35	in	in	ADP
ap-917	173	36	heart	heart	NOUN
ap-917	173	37	failure	failure	NOUN
ap-917	173	38	,	,	PUNCT
ap-917	173	39	reduced	reduce	VERB
ap-917	173	40	serca	serca	NOUN
ap-917	173	41	is	be	AUX
ap-917	173	42	consistently	consistently	ADV
ap-917	173	43	reported	report	VERB
ap-917	173	44	.	.	PUNCT
ap-917	174	1	in	in	ADP
ap-917	174	2	line	line	NOUN
ap-917	174	3	with	with	ADP
ap-917	174	4	this	this	PRON
ap-917	174	5	,	,	PUNCT
ap-917	174	6	lower	low	ADJ
ap-917	174	7	total	total	ADJ
ap-917	174	8	calcium	calcium	NOUN
ap-917	174	9	,	,	PUNCT
ap-917	174	10	calcium	calcium	NOUN
ap-917	174	11	peak	peak	NOUN
ap-917	174	12	and	and	CCONJ
ap-917	174	13	maximal	maximal	ADJ
ap-917	174	14	force	force	NOUN
ap-917	174	15	are	be	AUX
ap-917	174	16	found	find	VERB
ap-917	174	17	.	.	PUNCT
ap-917	175	1	however	however	ADV
ap-917	175	2	,	,	PUNCT
ap-917	175	3	reports	report	NOUN
ap-917	175	4	on	on	ADP
ap-917	175	5	the	the	DET
ap-917	175	6	role	role	NOUN
ap-917	175	7	of	of	ADP
ap-917	175	8	ncx	ncx	NOUN
ap-917	175	9	are	be	AUX
ap-917	175	10	almost	almost	ADV
ap-917	175	11	contradictory	contradictory	ADJ
ap-917	175	12	.	.	PUNCT
ap-917	176	1	o’rourke	o’rourke	NOUN
ap-917	177	1	[	[	X
ap-917	177	2	11	11	NUM
ap-917	177	3	]	]	PUNCT
ap-917	177	4	reports	report	NOUN
ap-917	177	5	increased	increase	VERB
ap-917	177	6	ncx	ncx	ADP
ap-917	177	7	that	that	PRON
ap-917	177	8	compensates	compensate	VERB
ap-917	177	9	defective	defective	ADJ
ap-917	177	10	serca	serca	NOUN
ap-917	177	11	in	in	ADP
ap-917	177	12	maintaining	maintain	VERB
ap-917	177	13	diastolic	diastolic	NOUN
ap-917	177	14	(	(	PUNCT
ap-917	177	15	relaxed	relaxed	ADJ
ap-917	177	16	)	)	PUNCT
ap-917	177	17	calcium	calcium	NOUN
ap-917	177	18	low	low	ADJ
ap-917	177	19	at	at	ADP
ap-917	177	20	the	the	DET
ap-917	177	21	cost	cost	NOUN
ap-917	177	22	of	of	ADP
ap-917	177	23	further	further	ADJ
ap-917	177	24	compromised	compromise	VERB
ap-917	177	25	systolic	systolic	ADJ
ap-917	177	26	(	(	PUNCT
ap-917	177	27	contraction	contraction	NOUN
ap-917	177	28	)	)	PUNCT
ap-917	177	29	performance	performance	NOUN
ap-917	177	30	.	.	PUNCT
ap-917	178	1	based	base	VERB
ap-917	178	2	on	on	ADP
ap-917	178	3	our	our	PRON
ap-917	178	4	results	result	NOUN
ap-917	178	5	,	,	PUNCT
ap-917	178	6	this	this	DET
ap-917	178	7	compensatory	compensatory	ADJ
ap-917	178	8	effect	effect	NOUN
ap-917	178	9	is	be	AUX
ap-917	178	10	relevant	relevant	ADJ
ap-917	178	11	mainly	mainly	ADV
ap-917	178	12	when	when	SCONJ
ap-917	178	13	the	the	DET
ap-917	178	14	heart	heart	NOUN
ap-917	178	15	rate	rate	NOUN
ap-917	178	16	is	be	AUX
ap-917	178	17	higher	high	ADJ
ap-917	178	18	.	.	PUNCT
ap-917	179	1	however	however	ADV
ap-917	179	2	,	,	PUNCT
ap-917	179	3	hobai	hobai	X
ap-917	180	1	[	[	X
ap-917	180	2	12	12	NUM
ap-917	180	3	]	]	PUNCT
ap-917	180	4	reports	report	VERB
ap-917	180	5	improved	improve	VERB
ap-917	180	6	cardiac	cardiac	ADJ
ap-917	180	7	function	function	NOUN
ap-917	180	8	in	in	ADP
ap-917	180	9	a	a	DET
ap-917	180	10	failing	fail	VERB
ap-917	180	11	heart	heart	NOUN
ap-917	180	12	after	after	ADP
ap-917	180	13	inhibition	inhibition	NOUN
ap-917	180	14	of	of	ADP
ap-917	180	15	increased	increase	VERB
ap-917	180	16	ncx	ncx	ADV
ap-917	180	17	by	by	ADP
ap-917	180	18	externally	externally	ADV
ap-917	180	19	administered	administer	VERB
ap-917	180	20	inhibitory	inhibitory	ADJ
ap-917	180	21	peptide	peptide	NOUN
ap-917	180	22	,	,	PUNCT
ap-917	180	23	and	and	CCONJ
ap-917	180	24	suggests	suggest	VERB
ap-917	180	25	ncx	ncx	ADP
ap-917	180	26	inhibition	inhibition	NOUN
ap-917	180	27	as	as	ADP
ap-917	180	28	a	a	DET
ap-917	180	29	promising	promising	ADJ
ap-917	180	30	treatment	treatment	NOUN
ap-917	180	31	for	for	ADP
ap-917	180	32	heart	heart	NOUN
ap-917	180	33	failure	failure	NOUN
ap-917	180	34	.	.	PUNCT
ap-917	181	1	this	this	DET
ap-917	181	2	finding	finding	NOUN
ap-917	181	3	may	may	AUX
ap-917	181	4	also	also	ADV
ap-917	181	5	be	be	AUX
ap-917	181	6	relevant	relevant	ADJ
ap-917	181	7	,	,	PUNCT
ap-917	181	8	however	however	ADV
ap-917	181	9	only	only	ADV
ap-917	181	10	when	when	SCONJ
ap-917	181	11	the	the	DET
ap-917	181	12	heart	heart	NOUN
ap-917	181	13	rate	rate	NOUN
ap-917	181	14	is	be	AUX
ap-917	181	15	low	low	ADJ
ap-917	181	16	(	(	PUNCT
ap-917	181	17	circa	circa	NOUN
ap-917	181	18	1	1	NUM
ap-917	181	19	hz	hz	X
ap-917	181	20	and	and	CCONJ
ap-917	181	21	less	less	ADJ
ap-917	181	22	)	)	PUNCT
ap-917	181	23	.	.	PUNCT
ap-917	182	1	blocking	block	VERB
ap-917	182	2	ncx	ncx	NOUN
ap-917	182	3	:	:	PUNCT
ap-917	182	4	a	a	X
ap-917	182	5	)	)	PUNCT
ap-917	182	6	increases	increase	VERB
ap-917	182	7	cellular	cellular	ADJ
ap-917	182	8	calcium	calcium	NOUN
ap-917	182	9	loading	loading	NOUN
ap-917	182	10	(	(	PUNCT
ap-917	182	11	and	and	CCONJ
ap-917	182	12	contractility	contractility	NOUN
ap-917	182	13	)	)	PUNCT
ap-917	182	14	,	,	PUNCT
ap-917	182	15	b	b	X
ap-917	182	16	)	)	PUNCT
ap-917	182	17	increases	increase	VERB
ap-917	182	18	diastolic	diastolic	ADJ
ap-917	182	19	ca2	ca2	PROPN
ap-917	182	20	�	�	PROPN
ap-917	182	21	.	.	PUNCT
ap-917	183	1	at	at	ADP
ap-917	183	2	low	low	ADJ
ap-917	183	3	heart	heart	NOUN
ap-917	183	4	rates	rate	NOUN
ap-917	183	5	,	,	PUNCT
ap-917	183	6	there	there	PRON
ap-917	183	7	is	be	VERB
ap-917	183	8	enough	enough	ADJ
ap-917	183	9	time	time	NOUN
ap-917	183	10	to	to	PART
ap-917	183	11	extrude	extrude	VERB
ap-917	183	12	this	this	DET
ap-917	183	13	increased	increase	VERB
ap-917	183	14	ca2	ca2	PROPN
ap-917	183	15	�	�	PROPN
ap-917	183	16	(	(	PUNCT
ap-917	183	17	fig	fig	NOUN
ap-917	183	18	.	.	PUNCT
ap-917	184	1	9	9	NUM
ap-917	184	2	)	)	PUNCT
ap-917	185	1	and	and	CCONJ
ap-917	185	2	so	so	ADV
ap-917	185	3	maintain	maintain	VERB
ap-917	185	4	relaxation	relaxation	NOUN
ap-917	185	5	.	.	PUNCT
ap-917	186	1	at	at	ADP
ap-917	186	2	low	low	ADJ
ap-917	186	3	rates	rate	NOUN
ap-917	186	4	overall	overall	ADJ
ap-917	186	5	stimulation	stimulation	NOUN
ap-917	186	6	predominates	predominate	VERB
ap-917	186	7	.	.	PUNCT
ap-917	187	1	at	at	ADP
ap-917	187	2	rates	rate	NOUN
ap-917	187	3	�	�	PROPN
ap-917	187	4	2	2	NUM
ap-917	187	5	hz	hz	VERB
ap-917	187	6	diastolic	diastolic	NOUN
ap-917	187	7	ca2	ca2	PROPN
ap-917	187	8	�	�	PROPN
ap-917	187	9	accumulates	accumulate	VERB
ap-917	187	10	,	,	PUNCT
ap-917	187	11	since	since	SCONJ
ap-917	187	12	it	it	PRON
ap-917	187	13	is	be	AUX
ap-917	187	14	not	not	PART
ap-917	187	15	sufficiently	sufficiently	ADV
ap-917	187	16	extruded	extrude	VERB
ap-917	187	17	and	and	CCONJ
ap-917	187	18	results	result	NOUN
ap-917	187	19	in	in	ADP
ap-917	187	20	incomplete	incomplete	ADJ
ap-917	187	21	relaxation	relaxation	NOUN
ap-917	187	22	(	(	PUNCT
ap-917	187	23	fig	fig	NOUN
ap-917	187	24	.	.	PUNCT
ap-917	187	25	10	10	NUM
ap-917	187	26	)	)	PUNCT
ap-917	187	27	.	.	PUNCT
ap-917	188	1	the	the	DET
ap-917	188	2	experiments	experiment	NOUN
ap-917	188	3	by	by	ADP
ap-917	188	4	hobai	hobai	NOUN
ap-917	188	5	were	be	AUX
ap-917	188	6	performed	perform	VERB
ap-917	188	7	at	at	ADP
ap-917	188	8	0.5	0.5	NUM
ap-917	188	9	hz	hz	VERB
ap-917	188	10	which	which	PRON
ap-917	188	11	may	may	AUX
ap-917	188	12	explain	explain	VERB
ap-917	188	13	why	why	SCONJ
ap-917	188	14	they	they	PRON
ap-917	188	15	reported	report	VERB
ap-917	188	16	a	a	DET
ap-917	188	17	generally	generally	ADV
ap-917	188	18	beneficial	beneficial	ADJ
ap-917	188	19	role	role	NOUN
ap-917	188	20	of	of	ADP
ap-917	188	21	ncx	ncx	ADJ
ap-917	188	22	inhibition	inhibition	NOUN
ap-917	188	23	.	.	PUNCT
ap-917	189	1	however	however	ADV
ap-917	189	2	,	,	PUNCT
ap-917	189	3	in	in	ADP
ap-917	189	4	clinical	clinical	ADJ
ap-917	189	5	cases	case	NOUN
ap-917	189	6	there	there	PRON
ap-917	189	7	could	could	AUX
ap-917	189	8	be	be	AUX
ap-917	189	9	double	double	ADJ
ap-917	189	10	-	-	PUNCT
ap-917	189	11	edged	edge	VERB
ap-917	189	12	effects	effect	NOUN
ap-917	189	13	,	,	PUNCT
ap-917	189	14	since	since	SCONJ
ap-917	189	15	the	the	DET
ap-917	189	16	heart	heart	NOUN
ap-917	189	17	frequency	frequency	NOUN
ap-917	189	18	can	can	AUX
ap-917	189	19	easily	easily	ADV
ap-917	189	20	reach	reach	VERB
ap-917	189	21	2	2	NUM
ap-917	189	22	hz	hz	NOUN
ap-917	189	23	.	.	PUNCT
ap-917	190	1	some	some	DET
ap-917	190	2	other	other	ADJ
ap-917	190	3	works	work	NOUN
ap-917	190	4	have	have	AUX
ap-917	190	5	suggested	suggest	VERB
ap-917	190	6	increased	increase	VERB
ap-917	190	7	cardiac	cardiac	ADJ
ap-917	190	8	reserve	reserve	NOUN
ap-917	190	9	performance	performance	NOUN
ap-917	190	10	after	after	ADP
ap-917	190	11	over	over	NOUN
ap-917	190	12	-	-	PUNCT
ap-917	190	13	expression	expression	NOUN
ap-917	190	14	of	of	ADP
ap-917	190	15	ncx	ncx	NOUN
ap-917	190	16	in	in	ADP
ap-917	190	17	a	a	DET
ap-917	190	18	failing	fail	VERB
ap-917	190	19	rabbit	rabbit	NOUN
ap-917	190	20	heart	heart	NOUN
ap-917	190	21	[	[	X
ap-917	190	22	13	13	NUM
ap-917	190	23	]	]	PUNCT
ap-917	190	24	.	.	PUNCT
ap-917	191	1	this	this	DET
ap-917	191	2	effect	effect	NOUN
ap-917	191	3	can	can	AUX
ap-917	191	4	not	not	PART
ap-917	191	5	be	be	AUX
ap-917	191	6	explained	explain	VERB
ap-917	191	7	by	by	ADP
ap-917	191	8	the	the	DET
ap-917	191	9	current	current	ADJ
ap-917	191	10	model	model	NOUN
ap-917	191	11	,	,	PUNCT
ap-917	191	12	and	and	CCONJ
ap-917	191	13	thus	thus	ADV
ap-917	191	14	requires	require	VERB
ap-917	191	15	further	further	ADJ
ap-917	191	16	mechanisms	mechanism	NOUN
ap-917	191	17	to	to	PART
ap-917	191	18	be	be	AUX
ap-917	191	19	identified	identify	VERB
ap-917	191	20	and	and	CCONJ
ap-917	191	21	included	include	VERB
ap-917	191	22	.	.	PUNCT
ap-917	192	1	no	no	ADV
ap-917	192	2	matter	matter	ADV
ap-917	192	3	how	how	SCONJ
ap-917	192	4	complex	complex	ADJ
ap-917	192	5	calcium	calcium	NOUN
ap-917	192	6	handling	handling	NOUN
ap-917	192	7	is	be	AUX
ap-917	192	8	,	,	PUNCT
ap-917	192	9	it	it	PRON
ap-917	192	10	must	must	AUX
ap-917	192	11	be	be	AUX
ap-917	192	12	true	true	ADJ
ap-917	192	13	that	that	SCONJ
ap-917	192	14	the	the	DET
ap-917	192	15	input	input	NOUN
ap-917	192	16	and	and	CCONJ
ap-917	192	17	output	output	NOUN
ap-917	192	18	of	of	ADP
ap-917	192	19	ca2	ca2	PROPN
ap-917	192	20	�	�	PROPN
ap-917	192	21	into	into	ADP
ap-917	192	22	and	and	CCONJ
ap-917	192	23	out	out	ADP
ap-917	192	24	of	of	ADP
ap-917	192	25	the	the	DET
ap-917	192	26	cytoplasm	cytoplasm	NOUN
ap-917	192	27	must	must	AUX
ap-917	192	28	generally	generally	ADV
ap-917	192	29	match	match	VERB
ap-917	192	30	.	.	PUNCT
ap-917	193	1	any	any	DET
ap-917	193	2	change	change	NOUN
ap-917	193	3	in	in	ADP
ap-917	193	4	one	one	NUM
ap-917	193	5	of	of	ADP
ap-917	193	6	the	the	DET
ap-917	193	7	transporting	transporting	ADJ
ap-917	193	8	mechanisms	mechanism	NOUN
ap-917	193	9	(	(	PUNCT
ap-917	193	10	serca	serca	PROPN
ap-917	193	11	,	,	PUNCT
ap-917	193	12	ncx	ncx	PROPN
ap-917	193	13	,	,	PUNCT
ap-917	193	14	others	other	NOUN
ap-917	193	15	)	)	PUNCT
ap-917	193	16	must	must	AUX
ap-917	193	17	be	be	AUX
ap-917	193	18	reflected	reflect	VERB
ap-917	193	19	by	by	ADP
ap-917	193	20	changes	change	NOUN
ap-917	193	21	in	in	ADP
ap-917	193	22	other	other	ADJ
ap-917	193	23	parameters	parameter	NOUN
ap-917	193	24	(	(	PUNCT
ap-917	193	25	cellular	cellular	ADJ
ap-917	193	26	ca2	ca2	PROPN
ap-917	193	27	�	�	PROPN
ap-917	193	28	stores	store	NOUN
ap-917	193	29	,	,	PUNCT
ap-917	193	30	free	free	PROPN
ap-917	193	31	ca2	ca2	PROPN
ap-917	193	32	�	�	PROPN
ap-917	193	33	i	i	PROPN
ap-917	193	34	,	,	PUNCT
ap-917	193	35	etc	etc	X
ap-917	193	36	.	.	X
ap-917	193	37	)	)	PUNCT
ap-917	194	1	the	the	DET
ap-917	194	2	major	major	ADJ
ap-917	194	3	role	role	NOUN
ap-917	194	4	of	of	ADP
ap-917	194	5	ncx	ncx	NOUN
ap-917	194	6	is	be	AUX
ap-917	194	7	in	in	ADP
ap-917	194	8	removing	remove	VERB
ap-917	194	9	ca2	ca2	PROPN
ap-917	194	10	�	�	PROPN
ap-917	194	11	,	,	PUNCT
ap-917	194	12	which	which	PRON
ap-917	194	13	(	(	PUNCT
ap-917	194	14	necessarily	necessarily	ADV
ap-917	194	15	)	)	PUNCT
ap-917	194	16	enters	enter	VERB
ap-917	194	17	the	the	DET
ap-917	194	18	cell	cell	NOUN
ap-917	194	19	through	through	ADP
ap-917	194	20	an	an	DET
ap-917	194	21	l	l	ADJ
ap-917	194	22	-	-	PUNCT
ap-917	194	23	type	type	NOUN
ap-917	194	24	channel	channel	NOUN
ap-917	194	25	(	(	PUNCT
ap-917	194	26	dhpr	dhpr	NOUN
ap-917	194	27	)	)	PUNCT
ap-917	194	28	from	from	ADP
ap-917	194	29	outside	outside	ADV
ap-917	194	30	during	during	ADP
ap-917	194	31	each	each	DET
ap-917	194	32	cycle	cycle	NOUN
ap-917	194	33	.	.	PUNCT
ap-917	195	1	thus	thus	ADV
ap-917	195	2	increased	increase	VERB
ap-917	195	3	ncx	ncx	ADP
ap-917	195	4	activity	activity	NOUN
ap-917	195	5	will	will	AUX
ap-917	195	6	always	always	ADV
ap-917	195	7	tend	tend	VERB
ap-917	195	8	to	to	PART
ap-917	195	9	unload	unload	VERB
ap-917	195	10	the	the	DET
ap-917	195	11	cell	cell	NOUN
ap-917	195	12	and	and	CCONJ
ap-917	195	13	compromise	compromise	NOUN
ap-917	195	14	heart	heart	NOUN
ap-917	195	15	contractility	contractility	NOUN
ap-917	195	16	.	.	PUNCT
ap-917	196	1	increased	increase	VERB
ap-917	196	2	ncx	ncx	ADP
ap-917	196	3	200	200	NUM
ap-917	196	4	%	%	NOUN
ap-917	196	5	combined	combine	VERB
ap-917	196	6	with	with	ADP
ap-917	196	7	reduced	reduced	ADJ
ap-917	196	8	serca	serca	NOUN
ap-917	196	9	50	50	NUM
ap-917	196	10	%	%	NOUN
ap-917	196	11	,	,	PUNCT
ap-917	196	12	as	as	SCONJ
ap-917	196	13	sometimes	sometimes	ADV
ap-917	196	14	reported	report	VERB
ap-917	196	15	in	in	ADP
ap-917	196	16	heart	heart	NOUN
ap-917	196	17	failure	failure	NOUN
ap-917	196	18	,	,	PUNCT
ap-917	196	19	would	would	AUX
ap-917	196	20	result	result	VERB
ap-917	196	21	in	in	ADP
ap-917	196	22	extreme	extreme	ADJ
ap-917	196	23	depletion	depletion	NOUN
ap-917	196	24	of	of	ADP
ap-917	196	25	internal	internal	ADJ
ap-917	196	26	calcium	calcium	NOUN
ap-917	196	27	and	and	CCONJ
ap-917	196	28	thus	thus	ADV
ap-917	196	29	the	the	DET
ap-917	196	30	force	force	NOUN
ap-917	196	31	that	that	PRON
ap-917	196	32	could	could	AUX
ap-917	196	33	be	be	AUX
ap-917	196	34	generated	generate	VERB
ap-917	196	35	is	be	AUX
ap-917	196	36	hardly	hardly	ADV
ap-917	196	37	sufficient	sufficient	ADJ
ap-917	196	38	.	.	PUNCT
ap-917	197	1	this	this	DET
ap-917	197	2	calculation	calculation	NOUN
ap-917	197	3	indirectly	indirectly	ADV
ap-917	197	4	suggests	suggest	VERB
ap-917	197	5	that	that	SCONJ
ap-917	197	6	another	another	DET
ap-917	197	7	mechanism	mechanism	NOUN
ap-917	197	8	must	must	AUX
ap-917	197	9	be	be	AUX
ap-917	197	10	involved	involve	VERB
ap-917	197	11	in	in	ADP
ap-917	197	12	ca2	ca2	PROPN
ap-917	197	13	�	�	PROPN
ap-917	197	14	handling	handling	NOUN
ap-917	197	15	changes	change	NOUN
ap-917	197	16	in	in	ADP
ap-917	197	17	heart	heart	NOUN
ap-917	197	18	failure	failure	NOUN
ap-917	197	19	.	.	PUNCT
ap-917	198	1	one	one	NUM
ap-917	198	2	option	option	NOUN
ap-917	198	3	is	be	AUX
ap-917	198	4	the	the	DET
ap-917	198	5	“	"	PUNCT
ap-917	198	6	reverse	reverse	ADJ
ap-917	198	7	mode	mode	NOUN
ap-917	198	8	”	"	PUNCT
ap-917	198	9	capability	capability	NOUN
ap-917	198	10	of	of	ADP
ap-917	198	11	ncx	ncx	NOUN
ap-917	198	12	in	in	ADP
ap-917	198	13	the	the	DET
ap-917	198	14	early	early	ADJ
ap-917	198	15	phase	phase	NOUN
ap-917	198	16	of	of	ADP
ap-917	198	17	a	a	DET
ap-917	198	18	cycle	cycle	NOUN
ap-917	198	19	.	.	PUNCT
ap-917	199	1	this	this	DET
ap-917	199	2	regime	regime	NOUN
ap-917	199	3	depends	depend	VERB
ap-917	199	4	on	on	ADP
ap-917	199	5	many	many	ADJ
ap-917	199	6	parameters	parameter	NOUN
ap-917	199	7	(	(	PUNCT
ap-917	199	8	na	na	PART
ap-917	199	9	�	�	PROPN
ap-917	199	10	and	and	CCONJ
ap-917	199	11	ca2	ca2	PROPN
ap-917	199	12	�	�	PROPN
ap-917	199	13	concentrations	concentration	NOUN
ap-917	199	14	,	,	PUNCT
ap-917	199	15	membrane	membrane	NOUN
ap-917	199	16	voltage	voltage	NOUN
ap-917	199	17	,	,	PUNCT
ap-917	199	18	ncx	ncx	ADP
ap-917	199	19	regulations	regulation	NOUN
ap-917	199	20	)	)	PUNCT
ap-917	199	21	and	and	CCONJ
ap-917	199	22	plays	play	VERB
ap-917	199	23	a	a	DET
ap-917	199	24	minor	minor	ADJ
ap-917	199	25	role	role	NOUN
ap-917	199	26	under	under	ADP
ap-917	199	27	physiological	physiological	ADJ
ap-917	199	28	conditions	condition	NOUN
ap-917	199	29	.	.	PUNCT
ap-917	200	1	however	however	ADV
ap-917	200	2	,	,	PUNCT
ap-917	200	3	to	to	PART
ap-917	200	4	make	make	VERB
ap-917	200	5	a	a	DET
ap-917	200	6	quantitative	quantitative	ADJ
ap-917	200	7	assessment	assessment	NOUN
ap-917	200	8	of	of	ADP
ap-917	200	9	this	this	DET
ap-917	200	10	effect	effect	NOUN
ap-917	200	11	and	and	CCONJ
ap-917	200	12	its	its	PRON
ap-917	200	13	contribution	contribution	NOUN
ap-917	200	14	to	to	ADP
ap-917	200	15	cell	cell	NOUN
ap-917	200	16	ca2	ca2	PROPN
ap-917	200	17	�	�	PROPN
ap-917	200	18	handling	handling	NOUN
ap-917	200	19	as	as	ADP
ap-917	200	20	a	a	DET
ap-917	200	21	whole	whole	NOUN
ap-917	200	22	,	,	PUNCT
ap-917	200	23	specifically	specifically	ADV
ap-917	200	24	in	in	ADP
ap-917	200	25	a	a	DET
ap-917	200	26	simulated	simulated	ADJ
ap-917	200	27	failing	fail	VERB
ap-917	200	28	heart	heart	NOUN
ap-917	200	29	,	,	PUNCT
ap-917	200	30	the	the	DET
ap-917	200	31	current	current	ADJ
ap-917	200	32	model	model	NOUN
ap-917	200	33	needs	need	VERB
ap-917	200	34	to	to	PART
ap-917	200	35	be	be	AUX
ap-917	200	36	refined	refine	VERB
ap-917	200	37	to	to	PART
ap-917	200	38	better	well	ADV
ap-917	200	39	reflect	reflect	VERB
ap-917	200	40	the	the	DET
ap-917	200	41	parameters	parameter	NOUN
ap-917	200	42	controlling	control	VERB
ap-917	200	43	the	the	DET
ap-917	200	44	ncx	ncx	ADJ
ap-917	200	45	reverse	reverse	ADJ
ap-917	200	46	mode	mode	NOUN
ap-917	200	47	.	.	PUNCT
ap-917	201	1	limitations	limitation	NOUN
ap-917	201	2	in	in	ADP
ap-917	201	3	biological	biological	ADJ
ap-917	201	4	systems	system	NOUN
ap-917	201	5	numerous	numerous	ADJ
ap-917	201	6	molecular	molecular	ADJ
ap-917	201	7	mechanisms	mechanism	NOUN
ap-917	201	8	contribute	contribute	VERB
ap-917	201	9	to	to	ADP
ap-917	201	10	ecc	ecc	PROPN
ap-917	201	11	.	.	PUNCT
ap-917	202	1	any	any	PRON
ap-917	202	2	of	of	ADP
ap-917	202	3	them	they	PRON
ap-917	202	4	can	can	AUX
ap-917	202	5	be	be	AUX
ap-917	202	6	altered	alter	VERB
ap-917	202	7	and	and	CCONJ
ap-917	202	8	many	many	ADJ
ap-917	202	9	may	may	AUX
ap-917	202	10	even	even	ADV
ap-917	202	11	not	not	PART
ap-917	202	12	have	have	AUX
ap-917	202	13	been	be	AUX
ap-917	202	14	identified	identify	VERB
ap-917	202	15	yet	yet	ADV
ap-917	202	16	.	.	PUNCT
ap-917	203	1	conversely	conversely	ADV
ap-917	203	2	,	,	PUNCT
ap-917	203	3	a	a	DET
ap-917	203	4	computational	computational	ADJ
ap-917	203	5	model	model	NOUN
ap-917	203	6	can	can	AUX
ap-917	203	7	only	only	ADV
ap-917	203	8	reflect	reflect	VERB
ap-917	203	9	a	a	DET
ap-917	203	10	very	very	ADV
ap-917	203	11	limited	limited	ADJ
ap-917	203	12	set	set	NOUN
ap-917	203	13	of	of	ADP
ap-917	203	14	the	the	DET
ap-917	203	15	mechanisms	mechanism	NOUN
ap-917	203	16	that	that	PRON
ap-917	203	17	are	be	AUX
ap-917	203	18	included	include	VERB
ap-917	203	19	in	in	ADP
ap-917	203	20	the	the	DET
ap-917	203	21	real	real	ADJ
ap-917	203	22	phenomenon	phenomenon	NOUN
ap-917	203	23	in	in	ADP
ap-917	203	24	real	real	ADJ
ap-917	203	25	life	life	NOUN
ap-917	203	26	.	.	PUNCT
ap-917	204	1	the	the	DET
ap-917	204	2	results	result	NOUN
ap-917	204	3	drawn	draw	VERB
ap-917	204	4	here	here	ADV
ap-917	204	5	should	should	AUX
ap-917	204	6	always	always	ADV
ap-917	204	7	be	be	AUX
ap-917	204	8	interpreted	interpret	VERB
ap-917	204	9	with	with	ADP
ap-917	204	10	caution	caution	NOUN
ap-917	204	11	.	.	PUNCT
ap-917	205	1	however	however	ADV
ap-917	205	2	,	,	PUNCT
ap-917	205	3	good	good	ADJ
ap-917	205	4	conformance	conformance	NOUN
ap-917	205	5	with	with	ADP
ap-917	205	6	experimental	experimental	ADJ
ap-917	205	7	data	datum	NOUN
ap-917	205	8	indicates	indicate	VERB
ap-917	205	9	that	that	SCONJ
ap-917	205	10	major	major	ADJ
ap-917	205	11	mechanisms	mechanism	NOUN
ap-917	205	12	have	have	AUX
ap-917	205	13	been	be	AUX
ap-917	205	14	identified	identify	VERB
ap-917	205	15	(	(	PUNCT
ap-917	205	16	e.g.	e.g.	ADV
ap-917	205	17	the	the	DET
ap-917	205	18	effect	effect	NOUN
ap-917	205	19	of	of	ADP
ap-917	205	20	ncx	ncx	NOUN
ap-917	205	21	at	at	ADP
ap-917	205	22	various	various	ADJ
ap-917	205	23	heart	heart	NOUN
ap-917	205	24	rates	rate	NOUN
ap-917	205	25	)	)	PUNCT
ap-917	205	26	.	.	PUNCT
ap-917	206	1	however	however	ADV
ap-917	206	2	,	,	PUNCT
ap-917	206	3	the	the	DET
ap-917	206	4	discrepancy	discrepancy	NOUN
ap-917	206	5	between	between	ADP
ap-917	206	6	the	the	DET
ap-917	206	7	simulated	simulate	VERB
ap-917	206	8	and	and	CCONJ
ap-917	206	9	experimental	experimental	ADJ
ap-917	206	10	data	datum	NOUN
ap-917	206	11	suggests	suggest	VERB
ap-917	206	12	that	that	SCONJ
ap-917	206	13	further	further	ADJ
ap-917	206	14	mechanisms	mechanism	NOUN
ap-917	206	15	need	need	VERB
ap-917	206	16	to	to	PART
ap-917	206	17	be	be	AUX
ap-917	206	18	searched	search	VERB
ap-917	206	19	for	for	ADP
ap-917	206	20	(	(	PUNCT
ap-917	206	21	e.g.	e.g.	ADV
ap-917	206	22	improved	improve	VERB
ap-917	206	23	contractility	contractility	NOUN
ap-917	206	24	after	after	ADP
ap-917	206	25	ncx	ncx	ADP
ap-917	206	26	stimulation	stimulation	NOUN
ap-917	206	27	in	in	ADP
ap-917	206	28	healthy	healthy	ADJ
ap-917	206	29	hearts	heart	NOUN
ap-917	206	30	)	)	PUNCT
ap-917	206	31	.	.	PUNCT
ap-917	207	1	in	in	ADP
ap-917	207	2	this	this	DET
ap-917	207	3	way	way	NOUN
ap-917	207	4	,	,	PUNCT
ap-917	207	5	simulations	simulation	NOUN
ap-917	207	6	can	can	AUX
ap-917	207	7	stimulate	stimulate	VERB
ap-917	207	8	and	and	CCONJ
ap-917	207	9	direct	direct	VERB
ap-917	207	10	biomedical	biomedical	ADJ
ap-917	207	11	research	research	NOUN
ap-917	207	12	,	,	PUNCT
ap-917	207	13	which	which	PRON
ap-917	207	14	has	have	AUX
ap-917	207	15	traditionally	traditionally	ADV
ap-917	207	16	relied	rely	VERB
ap-917	207	17	on	on	ADP
ap-917	207	18	experimental	experimental	ADJ
ap-917	207	19	approaches	approach	NOUN
ap-917	207	20	.	.	PUNCT
ap-917	208	1	5	5	NUM
ap-917	208	2	acknowledgment	acknowledgment	NOUN
ap-917	208	3	this	this	DET
ap-917	208	4	study	study	NOUN
ap-917	208	5	was	be	AUX
ap-917	208	6	supported	support	VERB
ap-917	208	7	by	by	ADP
ap-917	208	8	the	the	DET
ap-917	208	9	ministry	ministry	PROPN
ap-917	208	10	of	of	ADP
ap-917	208	11	education	education	PROPN
ap-917	208	12	,	,	PUNCT
ap-917	208	13	youth	youth	NOUN
ap-917	208	14	and	and	CCONJ
ap-917	208	15	sports	sport	NOUN
ap-917	208	16	of	of	ADP
ap-917	208	17	the	the	DET
ap-917	208	18	czech	czech	PROPN
ap-917	208	19	republic	republic	NOUN
ap-917	208	20	project	project	NOUN
ap-917	208	21	:	:	PUNCT
ap-917	208	22	transdisciplinary	transdisciplinary	ADJ
ap-917	208	23	research	research	NOUN
ap-917	208	24	in	in	ADP
ap-917	208	25	biomedical	biomedical	ADJ
ap-917	208	26	engineering	engineering	PROPN
ap-917	208	27	ii	ii	PROPN
ap-917	208	28	.	.	PROPN
ap-917	208	29	,	,	PUNCT
ap-917	208	30	no	no	INTJ
ap-917	208	31	.	.	PUNCT
ap-917	209	1	msm	msm	NOUN
ap-917	209	2	6840770012	6840770012	NUM
ap-917	209	3	and	and	CCONJ
ap-917	209	4	the	the	DET
ap-917	209	5	grant	grant	PROPN
ap-917	209	6	agency	agency	NOUN
ap-917	209	7	of	of	ADP
ap-917	209	8	the	the	DET
ap-917	209	9	czech	czech	PROPN
ap-917	209	10	republic	republic	NOUN
ap-917	209	11	,	,	PUNCT
ap-917	209	12	project	project	NOUN
ap-917	209	13	no	no	NOUN
ap-917	209	14	.	.	PUNCT
ap-917	210	1	106/04/1181	106/04/1181	NUM
ap-917	210	2	,	,	PUNCT
ap-917	210	3	and	and	CCONJ
ap-917	210	4	czech	czech	PROPN
ap-917	210	5	academy	academy	NOUN
ap-917	210	6	of	of	ADP
ap-917	210	7	sciences	science	NOUN
ap-917	210	8	1et201210527	1et201210527	NUM
ap-917	210	9	.	.	PUNCT
ap-917	211	1	references	reference	NOUN
ap-917	211	2	[	[	X
ap-917	211	3	1	1	NUM
ap-917	211	4	]	]	X
ap-917	211	5	di	di	X
ap-917	211	6	francesco	francesco	PROPN
ap-917	211	7	,	,	PUNCT
ap-917	211	8	d.	d.	PROPN
ap-917	211	9	–	–	PUNCT
ap-917	211	10	noble	noble	ADJ
ap-917	211	11	,	,	PUNCT
ap-917	211	12	d.	d.	PROPN
ap-917	211	13	:	:	PUNCT
ap-917	211	14	a	a	DET
ap-917	211	15	model	model	NOUN
ap-917	211	16	of	of	ADP
ap-917	211	17	cardiac	cardiac	ADJ
ap-917	211	18	electrical	electrical	ADJ
ap-917	211	19	activity	activity	NOUN
ap-917	211	20	incorporating	incorporate	VERB
ap-917	211	21	ionic	ionic	ADJ
ap-917	211	22	pumps	pump	NOUN
ap-917	211	23	and	and	CCONJ
ap-917	211	24	concentration	concentration	NOUN
ap-917	211	25	changes	change	NOUN
ap-917	211	26	–	–	PUNCT
ap-917	211	27	simulations	simulation	NOUN
ap-917	211	28	of	of	ADP
ap-917	211	29	ionic	ionic	ADJ
ap-917	211	30	currents	current	NOUN
ap-917	211	31	and	and	CCONJ
ap-917	211	32	concentration	concentration	NOUN
ap-917	211	33	changes	change	NOUN
ap-917	211	34	.	.	PUNCT
ap-917	212	1	philos.trans	philos.tran	NOUN
ap-917	212	2	.	.	PUNCT
ap-917	212	3	r.	r.	PROPN
ap-917	212	4	soc	soc	PROPN
ap-917	212	5	.	.	PUNCT
ap-917	213	1	lond	lond	PROPN
ap-917	213	2	b	b	PROPN
ap-917	213	3	biol	biol	PROPN
ap-917	213	4	.	.	PUNCT
ap-917	214	1	sci	sci	PROPN
ap-917	214	2	.	.	PROPN
ap-917	214	3	,	,	PUNCT
ap-917	214	4	1985	1985	NUM
ap-917	214	5	,	,	PUNCT
ap-917	214	6	vol	vol	NOUN
ap-917	214	7	.	.	PROPN
ap-917	214	8	307	307	NUM
ap-917	214	9	,	,	PUNCT
ap-917	214	10	p.	p.	NOUN
ap-917	214	11	353–398	353–398	NUM
ap-917	214	12	.	.	PUNCT
ap-917	215	1	[	[	X
ap-917	215	2	2	2	NUM
ap-917	215	3	]	]	X
ap-917	215	4	hasenfuss	hasenfuss	ADJ
ap-917	215	5	,	,	PUNCT
ap-917	215	6	g.	g.	PROPN
ap-917	215	7	et	et	PROPN
ap-917	215	8	al	al	PROPN
ap-917	215	9	.	.	PROPN
ap-917	215	10	:	:	PUNCT
ap-917	216	1	relationship	relationship	NOUN
ap-917	216	2	between	between	ADP
ap-917	216	3	na	na	PART
ap-917	216	4	�	�	PROPN
ap-917	216	5	ca2	ca2	PROPN
ap-917	216	6	�	�	PROPN
ap-917	216	7	-exchanger	-exchanger	PROPN
ap-917	216	8	protein	protein	NOUN
ap-917	216	9	levels	level	NOUN
ap-917	216	10	and	and	CCONJ
ap-917	216	11	diastolic	diastolic	ADJ
ap-917	216	12	function	function	NOUN
ap-917	216	13	of	of	ADP
ap-917	216	14	failing	fail	VERB
ap-917	216	15	human	human	ADJ
ap-917	216	16	myocardium	myocardium	NOUN
ap-917	216	17	.	.	PUNCT
ap-917	217	1	circulation	circulation	NOUN
ap-917	217	2	,	,	PUNCT
ap-917	217	3	1999	1999	NUM
ap-917	217	4	,	,	PUNCT
ap-917	217	5	vol	vol	NOUN
ap-917	217	6	.	.	PROPN
ap-917	217	7	99	99	NUM
ap-917	217	8	,	,	PUNCT
ap-917	217	9	p.	p.	NOUN
ap-917	217	10	641–648	641–648	NUM
ap-917	217	11	.	.	PUNCT
ap-917	218	1	[	[	X
ap-917	218	2	3	3	NUM
ap-917	218	3	]	]	X
ap-917	218	4	huke	huke	PROPN
ap-917	218	5	,	,	PUNCT
ap-917	218	6	s.	s.	PROPN
ap-917	218	7	et	et	PROPN
ap-917	218	8	al	al	PROPN
ap-917	218	9	.	.	PROPN
ap-917	218	10	:	:	PUNCT
ap-917	218	11	altered	alter	VERB
ap-917	218	12	force	force	NOUN
ap-917	218	13	-	-	PUNCT
ap-917	218	14	frequency	frequency	NOUN
ap-917	218	15	response	response	NOUN
ap-917	218	16	in	in	ADP
ap-917	218	17	non	non	ADJ
ap-917	218	18	-	-	ADJ
ap-917	218	19	failing	failing	ADJ
ap-917	218	20	hearts	heart	NOUN
ap-917	218	21	with	with	ADP
ap-917	218	22	decreased	decrease	VERB
ap-917	218	23	serca	serca	NOUN
ap-917	218	24	pump	pump	NOUN
ap-917	218	25	-	-	PUNCT
ap-917	218	26	level	level	NOUN
ap-917	218	27	.	.	PUNCT
ap-917	219	1	cardiovasc	cardiovasc	PROPN
ap-917	219	2	.	.	PUNCT
ap-917	220	1	res	res	PROPN
ap-917	220	2	.	.	PROPN
ap-917	220	3	,	,	PUNCT
ap-917	220	4	2003	2003	NUM
ap-917	220	5	,	,	PUNCT
ap-917	220	6	vol	vol	NOUN
ap-917	220	7	.	.	PROPN
ap-917	220	8	59	59	NUM
ap-917	220	9	,	,	PUNCT
ap-917	220	10	p.	p.	NOUN
ap-917	220	11	668–677	668–677	NUM
ap-917	220	12	.	.	PUNCT
ap-917	221	1	[	[	X
ap-917	221	2	4	4	NUM
ap-917	221	3	]	]	X
ap-917	221	4	hasenfuss	hasenfuss	ADJ
ap-917	221	5	,	,	PUNCT
ap-917	221	6	g.	g.	PROPN
ap-917	221	7	–	–	PUNCT
ap-917	221	8	schillinger	schillinger	NOUN
ap-917	221	9	,	,	PUNCT
ap-917	221	10	w.	w.	PROPN
ap-917	221	11	:	:	PUNCT
ap-917	221	12	is	be	AUX
ap-917	221	13	modulation	modulation	NOUN
ap-917	221	14	of	of	ADP
ap-917	221	15	sodium	sodium	NOUN
ap-917	221	16	-	-	PUNCT
ap-917	221	17	calcium	calcium	NOUN
ap-917	221	18	exchange	exchange	NOUN
ap-917	221	19	a	a	DET
ap-917	221	20	therapeutic	therapeutic	ADJ
ap-917	221	21	option	option	NOUN
ap-917	221	22	in	in	ADP
ap-917	221	23	heart	heart	NOUN
ap-917	221	24	failure	failure	NOUN
ap-917	221	25	?	?	PUNCT
ap-917	222	1	circ.res	circ.re	NOUN
ap-917	222	2	.	.	NOUN
ap-917	222	3	,	,	PUNCT
ap-917	222	4	2004	2004	NUM
ap-917	222	5	,	,	PUNCT
ap-917	222	6	vol	vol	NOUN
ap-917	222	7	.	.	PROPN
ap-917	222	8	95	95	NUM
ap-917	222	9	,	,	PUNCT
ap-917	222	10	p.	p.	NOUN
ap-917	222	11	225–227	225–227	NUM
ap-917	222	12	.	.	PUNCT
ap-917	223	1	[	[	X
ap-917	223	2	5	5	NUM
ap-917	223	3	]	]	X
ap-917	223	4	pieske	pieske	PROPN
ap-917	223	5	,	,	PUNCT
ap-917	223	6	b.	b.	PROPN
ap-917	223	7	et	et	PROPN
ap-917	223	8	al	al	PROPN
ap-917	223	9	.	.	PUNCT
ap-917	223	10	:	:	PUNCT
ap-917	224	1	functional	functional	ADJ
ap-917	224	2	effects	effect	NOUN
ap-917	224	3	of	of	ADP
ap-917	224	4	endothelin	endothelin	PROPN
ap-917	224	5	and	and	CCONJ
ap-917	224	6	regulation	regulation	NOUN
ap-917	224	7	of	of	ADP
ap-917	224	8	endothelin	endothelin	PROPN
ap-917	224	9	receptors	receptor	NOUN
ap-917	224	10	in	in	ADP
ap-917	224	11	isolated	isolated	ADJ
ap-917	224	12	human	human	ADJ
ap-917	224	13	nonfailing	nonfailing	NOUN
ap-917	224	14	and	and	CCONJ
ap-917	224	15	failing	fail	VERB
ap-917	224	16	myocardium	myocardium	NOUN
ap-917	224	17	.	.	PUNCT
ap-917	225	1	circulation	circulation	NOUN
ap-917	225	2	,	,	PUNCT
ap-917	225	3	1999	1999	NUM
ap-917	225	4	,	,	PUNCT
ap-917	225	5	vol	vol	NOUN
ap-917	225	6	.	.	PROPN
ap-917	225	7	99	99	NUM
ap-917	225	8	,	,	PUNCT
ap-917	225	9	p.	p.	NOUN
ap-917	225	10	1802–1809	1802–1809	NUM
ap-917	225	11	.	.	PUNCT
ap-917	226	1	[	[	X
ap-917	226	2	6	6	NUM
ap-917	226	3	]	]	PUNCT
ap-917	226	4	mlček	mlček	NOUN
ap-917	226	5	,	,	PUNCT
ap-917	226	6	m.	m.	NOUN
ap-917	226	7	et	et	PROPN
ap-917	226	8	al	al	PROPN
ap-917	226	9	.	.	PUNCT
ap-917	226	10	:	:	PUNCT
ap-917	227	1	mathematical	mathematical	ADJ
ap-917	227	2	model	model	NOUN
ap-917	227	3	of	of	ADP
ap-917	227	4	the	the	DET
ap-917	227	5	electromechanical	electromechanical	ADJ
ap-917	227	6	heart	heart	NOUN
ap-917	227	7	contractile	contractile	NOUN
ap-917	227	8	system	system	NOUN
ap-917	227	9	—	—	PUNCT
ap-917	227	10	regulatory	regulatory	ADJ
ap-917	227	11	subsystem	subsystem	NOUN
ap-917	227	12	physiological	physiological	ADJ
ap-917	227	13	considerations	consideration	NOUN
ap-917	227	14	.	.	PUNCT
ap-917	228	1	physiol	physiol	PROPN
ap-917	228	2	res	res	PROPN
ap-917	228	3	.	.	PROPN
ap-917	228	4	,	,	PUNCT
ap-917	228	5	2001	2001	NUM
ap-917	228	6	,	,	PUNCT
ap-917	228	7	vol	vol	NOUN
ap-917	228	8	.	.	PROPN
ap-917	228	9	50	50	NUM
ap-917	228	10	,	,	PUNCT
ap-917	228	11	p.	p.	NOUN
ap-917	228	12	425	425	NUM
ap-917	228	13	-	-	SYM
ap-917	228	14	432	432	NUM
ap-917	228	15	.	.	PUNCT
ap-917	229	1	[	[	X
ap-917	229	2	7	7	NUM
ap-917	229	3	]	]	X
ap-917	229	4	novak	novak	PROPN
ap-917	229	5	,	,	PUNCT
ap-917	229	6	v.	v.	PROPN
ap-917	229	7	–	–	PUNCT
ap-917	229	8	neumann	neumann	PROPN
ap-917	229	9	,	,	PUNCT
ap-917	229	10	j.	j.	PROPN
ap-917	229	11	:	:	PUNCT
ap-917	229	12	mathematical	mathematical	ADJ
ap-917	229	13	model	model	NOUN
ap-917	229	14	of	of	ADP
ap-917	229	15	the	the	DET
ap-917	229	16	electromechanical	electromechanical	ADJ
ap-917	229	17	heart	heart	NOUN
ap-917	229	18	contractile	contractile	NOUN
ap-917	229	19	system	system	NOUN
ap-917	229	20	–	–	PUNCT
ap-917	229	21	simulation	simulation	NOUN
ap-917	229	22	results	result	VERB
ap-917	229	23	.	.	PUNCT
ap-917	230	1	international	international	ADJ
ap-917	230	2	journal	journal	PROPN
ap-917	230	3	of	of	ADP
ap-917	230	4	bioelectromagnetism	bioelectromagnetism	NOUN
ap-917	230	5	,	,	PUNCT
ap-917	230	6	2000	2000	NUM
ap-917	230	7	,	,	PUNCT
ap-917	230	8	vol.2	vol.2	PROPN
ap-917	230	9	,	,	PUNCT
ap-917	230	10	no	no	INTJ
ap-917	230	11	.	.	NOUN
ap-917	230	12	2	2	NUM
ap-917	230	13	,	,	PUNCT
ap-917	230	14	electronic	electronic	ADJ
ap-917	230	15	version	version	NOUN
ap-917	230	16	.	.	PUNCT
ap-917	231	1	[	[	X
ap-917	231	2	8	8	NUM
ap-917	231	3	]	]	X
ap-917	231	4	winslow	winslow	PROPN
ap-917	231	5	,	,	PUNCT
ap-917	231	6	r.	r.	PROPN
ap-917	231	7	l.	l.	PROPN
ap-917	231	8	et	et	PROPN
ap-917	231	9	al	al	PROPN
ap-917	231	10	.	.	PROPN
ap-917	231	11	:	:	PUNCT
ap-917	231	12	mechanisms	mechanism	NOUN
ap-917	231	13	of	of	ADP
ap-917	231	14	altered	altered	ADJ
ap-917	231	15	excitation	excitation	NOUN
ap-917	231	16	-	-	PUNCT
ap-917	231	17	contraction	contraction	NOUN
ap-917	231	18	coupling	coupling	NOUN
ap-917	231	19	in	in	ADP
ap-917	231	20	canine	canine	NOUN
ap-917	231	21	tachycardia	tachycardia	NOUN
ap-917	231	22	-	-	PUNCT
ap-917	231	23	induced	induce	VERB
ap-917	231	24	heart	heart	NOUN
ap-917	231	25	failure	failure	NOUN
ap-917	231	26	,	,	PUNCT
ap-917	231	27	ii	ii	PROPN
ap-917	231	28	:	:	PUNCT
ap-917	231	29	model	model	NOUN
ap-917	231	30	studies	study	NOUN
ap-917	231	31	.	.	PUNCT
ap-917	232	1	circ.res	circ.re	NOUN
ap-917	232	2	.	.	NUM
ap-917	232	3	,	,	PUNCT
ap-917	232	4	1999	1999	NUM
ap-917	232	5	,	,	PUNCT
ap-917	232	6	vol	vol	NOUN
ap-917	232	7	.	.	PROPN
ap-917	232	8	84	84	NUM
ap-917	232	9	,	,	PUNCT
ap-917	232	10	p.	p.	NOUN
ap-917	232	11	571–586	571–586	NUM
ap-917	232	12	.	.	PUNCT
ap-917	233	1	[	[	X
ap-917	233	2	9	9	NUM
ap-917	233	3	]	]	PUNCT
ap-917	233	4	trautwein	trautwein	PROPN
ap-917	233	5	,	,	PUNCT
ap-917	233	6	w.	w.	PROPN
ap-917	233	7	–	–	PUNCT
ap-917	233	8	kassebaum	kassebaum	PROPN
ap-917	233	9	,	,	PUNCT
ap-917	233	10	d.	d.	PROPN
ap-917	233	11	g.	g.	PROPN
ap-917	233	12	:	:	PUNCT
ap-917	233	13	.	.	PUNCT
ap-917	234	1	electrophysiological	electrophysiological	ADJ
ap-917	234	2	study	study	NOUN
ap-917	234	3	of	of	ADP
ap-917	234	4	human	human	ADJ
ap-917	234	5	heart	heart	NOUN
ap-917	234	6	muscle	muscle	NOUN
ap-917	234	7	.	.	PUNCT
ap-917	235	1	circ	circ	PROPN
ap-917	235	2	res	re	NOUN
ap-917	235	3	,	,	PUNCT
ap-917	235	4	1962	1962	NUM
ap-917	235	5	,	,	PUNCT
ap-917	235	6	vol	vol	NOUN
ap-917	235	7	.	.	PROPN
ap-917	235	8	10	10	NUM
ap-917	235	9	,	,	PUNCT
ap-917	235	10	p.	p.	NOUN
ap-917	235	11	306–312	306–312	NUM
ap-917	235	12	.	.	PUNCT
ap-917	236	1	[	[	X
ap-917	236	2	10	10	NUM
ap-917	236	3	]	]	X
ap-917	236	4	beuckelmann	beuckelmann	PROPN
ap-917	236	5	,	,	PUNCT
ap-917	236	6	d.	d.	PROPN
ap-917	236	7	j.	j.	PROPN
ap-917	236	8	–	–	PUNCT
ap-917	236	9	nabauer	nabauer	NOUN
ap-917	236	10	,	,	PUNCT
ap-917	236	11	m.	m.	NOUN
ap-917	236	12	–	–	PUNCT
ap-917	236	13	erdmann	erdmann	NOUN
ap-917	236	14	,	,	PUNCT
ap-917	236	15	e.	e.	NOUN
ap-917	236	16	:	:	PUNCT
ap-917	236	17	intracellular	intracellular	ADJ
ap-917	236	18	calcium	calcium	NOUN
ap-917	236	19	handling	handling	NOUN
ap-917	236	20	in	in	ADP
ap-917	236	21	isolated	isolated	ADJ
ap-917	236	22	ventricular	ventricular	ADJ
ap-917	236	23	myocytes	myocyte	NOUN
ap-917	236	24	from	from	ADP
ap-917	236	25	patients	patient	NOUN
ap-917	236	26	with	with	ADP
ap-917	236	27	terminal	terminal	ADJ
ap-917	236	28	heart	heart	NOUN
ap-917	236	29	failure	failure	NOUN
ap-917	236	30	.	.	PUNCT
ap-917	237	1	circulation	circulation	NOUN
ap-917	237	2	,	,	PUNCT
ap-917	237	3	1992	1992	NUM
ap-917	237	4	,	,	PUNCT
ap-917	237	5	vol	vol	NOUN
ap-917	237	6	.	.	PROPN
ap-917	237	7	85	85	NUM
ap-917	237	8	,	,	PUNCT
ap-917	237	9	p.	p.	NOUN
ap-917	237	10	1046–1055	1046–1055	NUM
ap-917	237	11	.	.	PUNCT
ap-917	238	1	©	©	PROPN
ap-917	238	2	czech	czech	PROPN
ap-917	238	3	technical	technical	PROPN
ap-917	238	4	university	university	PROPN
ap-917	238	5	publishing	publishing	NOUN
ap-917	238	6	house	house	NOUN
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ap-917	238	8	9	9	NUM
ap-917	238	9	acta	acta	PROPN
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ap-917	238	11	vol	vol	NOUN
ap-917	238	12	.	.	PUNCT
ap-917	239	1	48	48	NUM
ap-917	239	2	no	no	NOUN
ap-917	239	3	.	.	PUNCT
ap-917	240	1	1/2008	1/2008	NUM
ap-917	241	1	[	[	X
ap-917	241	2	11	11	NUM
ap-917	241	3	]	]	PUNCT
ap-917	241	4	o’rourke	o’rourke	NOUN
ap-917	241	5	,	,	PUNCT
ap-917	241	6	b.	b.	PROPN
ap-917	241	7	et	et	PROPN
ap-917	241	8	al	al	PROPN
ap-917	241	9	.	.	PROPN
ap-917	241	10	:	:	PUNCT
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ap-917	241	12	of	of	ADP
ap-917	241	13	altered	altered	ADJ
ap-917	241	14	excitation	excitation	NOUN
ap-917	241	15	-	-	PUNCT
ap-917	241	16	contraction	contraction	NOUN
ap-917	241	17	coupling	coupling	NOUN
ap-917	241	18	in	in	ADP
ap-917	241	19	canine	canine	NOUN
ap-917	241	20	tachycardia	tachycardia	NOUN
ap-917	241	21	-	-	PUNCT
ap-917	241	22	induced	induce	VERB
ap-917	241	23	heart	heart	NOUN
ap-917	241	24	failure	failure	NOUN
ap-917	241	25	,	,	PUNCT
ap-917	241	26	i	i	PRON
ap-917	241	27	:	:	PUNCT
ap-917	241	28	experimental	experimental	ADJ
ap-917	241	29	studies	study	NOUN
ap-917	241	30	.	.	PUNCT
ap-917	242	1	circ.res	circ.re	NOUN
ap-917	242	2	.	.	NUM
ap-917	242	3	,	,	PUNCT
ap-917	242	4	1999	1999	NUM
ap-917	242	5	,	,	PUNCT
ap-917	242	6	vol	vol	NOUN
ap-917	242	7	.	.	PROPN
ap-917	242	8	84	84	NUM
ap-917	242	9	,	,	PUNCT
ap-917	242	10	p.	p.	NOUN
ap-917	242	11	562–570	562–570	NUM
ap-917	242	12	.	.	PUNCT
ap-917	243	1	[	[	X
ap-917	243	2	12	12	NUM
ap-917	243	3	]	]	X
ap-917	243	4	hobai	hobai	PROPN
ap-917	243	5	,	,	PUNCT
ap-917	243	6	i.	i.	NOUN
ap-917	243	7	a.	a.	PROPN
ap-917	243	8	–	–	PUNCT
ap-917	243	9	maack	maack	NOUN
ap-917	243	10	,	,	PUNCT
ap-917	243	11	c.	c.	NOUN
ap-917	243	12	–	–	PUNCT
ap-917	243	13	o’rourke	o’rourke	NOUN
ap-917	243	14	,	,	PUNCT
ap-917	243	15	b.	b.	NOUN
ap-917	243	16	:	:	PUNCT
ap-917	243	17	partial	partial	ADJ
ap-917	243	18	inhibition	inhibition	NOUN
ap-917	243	19	of	of	ADP
ap-917	243	20	sodium	sodium	NOUN
ap-917	243	21	/	/	SYM
ap-917	243	22	calcium	calcium	NOUN
ap-917	243	23	exchange	exchange	NOUN
ap-917	243	24	restores	restore	VERB
ap-917	243	25	cellular	cellular	ADJ
ap-917	243	26	calcium	calcium	NOUN
ap-917	243	27	handling	handling	NOUN
ap-917	243	28	in	in	ADP
ap-917	243	29	canine	canine	NOUN
ap-917	243	30	heart	heart	NOUN
ap-917	243	31	failure	failure	NOUN
ap-917	243	32	.	.	PUNCT
ap-917	244	1	circ.res	circ.re	NOUN
ap-917	244	2	.	.	NUM
ap-917	244	3	,	,	PUNCT
ap-917	244	4	2004	2004	NUM
ap-917	244	5	,	,	PUNCT
ap-917	244	6	vol	vol	NOUN
ap-917	244	7	.	.	PROPN
ap-917	244	8	95	95	NUM
ap-917	244	9	,	,	PUNCT
ap-917	244	10	p.	p.	NOUN
ap-917	244	11	292–299	292–299	NUM
ap-917	244	12	.	.	PUNCT
ap-917	245	1	[	[	X
ap-917	245	2	13	13	NUM
ap-917	245	3	]	]	X
ap-917	245	4	munch	munch	PROPN
ap-917	245	5	,	,	PUNCT
ap-917	245	6	g.	g.	PROPN
ap-917	245	7	et	et	PROPN
ap-917	245	8	al	al	PROPN
ap-917	245	9	.	.	PUNCT
ap-917	245	10	:	:	PUNCT
ap-917	246	1	functional	functional	ADJ
ap-917	246	2	alterations	alteration	NOUN
ap-917	246	3	after	after	ADP
ap-917	246	4	cardiac	cardiac	ADJ
ap-917	246	5	sodium	sodium	NOUN
ap-917	246	6	-	-	PUNCT
ap-917	246	7	calcium	calcium	NOUN
ap-917	246	8	exchanger	exchanger	NOUN
ap-917	246	9	overexpression	overexpression	NOUN
ap-917	246	10	in	in	ADP
ap-917	246	11	heart	heart	NOUN
ap-917	246	12	failure	failure	NOUN
ap-917	246	13	.	.	PUNCT
ap-917	247	1	am	be	AUX
ap-917	247	2	.	.	PUNCT
ap-917	248	1	j.	j.	PROPN
ap-917	248	2	physiol	physiol	PROPN
ap-917	248	3	heart	heart	PROPN
ap-917	248	4	circ.physiol	circ.physiol	PROPN
ap-917	248	5	,	,	PUNCT
ap-917	248	6	2006	2006	NUM
ap-917	248	7	,	,	PUNCT
ap-917	248	8	vol	vol	NOUN
ap-917	248	9	.	.	NOUN
ap-917	248	10	291	291	NUM
ap-917	248	11	,	,	PUNCT
ap-917	248	12	p.	p.	NOUN
ap-917	248	13	h488	h488	PROPN
ap-917	248	14	–	–	PUNCT
ap-917	248	15	h495	h495	NUM
ap-917	248	16	.	.	PUNCT
ap-917	248	17	martin	martin	PROPN
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ap-917	248	19	,	,	PUNCT
ap-917	248	20	msc	msc	PROPN
ap-917	248	21	.	.	PROPN
ap-917	248	22	phone	phone	PROPN
ap-917	248	23	:	:	PUNCT
ap-917	248	24	+420	+420	PROPN
ap-917	248	25	224	224	NUM
ap-917	248	26	352	352	NUM
ap-917	248	27	542	542	NUM
ap-917	248	28	e	e	NOUN
ap-917	248	29	-	-	NOUN
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ap-917	248	31	:	:	PUNCT
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ap-917	248	33	department	department	PROPN
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ap-917	248	36	,	,	PUNCT
ap-917	248	37	biomechanics	biomechanic	NOUN
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ap-917	248	39	mechatronics	mechatronic	NOUN
ap-917	248	40	czech	czech	PROPN
ap-917	248	41	technical	technical	PROPN
ap-917	248	42	university	university	PROPN
ap-917	248	43	faculty	faculty	NOUN
ap-917	248	44	of	of	ADP
ap-917	248	45	mechanical	mechanical	ADJ
ap-917	248	46	engineering	engineering	NOUN
ap-917	248	47	technická	technická	NOUN
ap-917	248	48	4	4	NUM
ap-917	248	49	166	166	NUM
ap-917	248	50	07	07	NUM
ap-917	248	51	prague	prague	NOUN
ap-917	248	52	6	6	NUM
ap-917	248	53	,	,	PUNCT
ap-917	248	54	czech	czech	PROPN
ap-917	248	55	republic	republic	NOUN
ap-917	248	56	mikuláš	mikuláš	NOUN
ap-917	248	57	mlček	mlček	PROPN
ap-917	248	58	,	,	PUNCT
ap-917	248	59	md	md	PROPN
ap-917	248	60	,	,	PUNCT
ap-917	248	61	ph.d	ph.d	PROPN
ap-917	248	62	.	.	PUNCT
ap-917	248	63	phone	phone	NOUN
ap-917	248	64	:	:	PUNCT
ap-917	248	65	+420	+420	PROPN
ap-917	248	66	224	224	NUM
ap-917	248	67	968	968	NUM
ap-917	248	68	407	407	NUM
ap-917	248	69	e	e	NOUN
ap-917	248	70	-	-	NOUN
ap-917	248	71	mail	mail	NOUN
ap-917	248	72	:	:	PUNCT
ap-917	248	73	mikulas.mlcek@lf1.cuni.cz	mikulas.mlcek@lf1.cuni.cz	NUM
ap-917	248	74	institute	institute	NOUN
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ap-917	248	76	physiology	physiology	PROPN
ap-917	248	77	charles	charles	PROPN
ap-917	248	78	university	university	PROPN
ap-917	248	79	first	first	ADJ
ap-917	248	80	faculty	faculty	NOUN
ap-917	248	81	of	of	ADP
ap-917	248	82	medicine	medicine	NOUN
ap-917	248	83	albertov	albertov	PROPN
ap-917	248	84	5	5	NUM
ap-917	248	85	128	128	NUM
ap-917	248	86	00	00	NUM
ap-917	248	87	prague	prague	PROPN
ap-917	248	88	2	2	NUM
ap-917	248	89	,	,	PUNCT
ap-917	248	90	czech	czech	PROPN
ap-917	248	91	republic	republic	NOUN
ap-917	248	92	svatava	svatava	PROPN
ap-917	248	93	konvičková	konvičková	PROPN
ap-917	248	94	,	,	PUNCT
ap-917	248	95	msc	msc	PROPN
ap-917	248	96	,	,	PUNCT
ap-917	248	97	ph.d	ph.d	PROPN
ap-917	248	98	.	.	PUNCT
ap-917	248	99	phone	phone	NOUN
ap-917	248	100	:	:	PUNCT
ap-917	248	101	+420	+420	PROPN
ap-917	248	102	224	224	NUM
ap-917	248	103	352	352	NUM
ap-917	248	104	511	511	NUM
ap-917	248	105	e	e	NOUN
ap-917	248	106	-	-	NOUN
ap-917	248	107	mail	mail	NOUN
ap-917	248	108	:	:	PUNCT
ap-917	248	109	svatava.konvickova@fs.cvut.cz	svatava.konvickova@fs.cvut.cz	PROPN
ap-917	248	110	department	department	PROPN
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ap-917	248	112	mechanics	mechanic	NOUN
ap-917	248	113	,	,	PUNCT
ap-917	248	114	biomechanics	biomechanic	NOUN
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ap-917	248	116	mechatronics	mechatronic	NOUN
ap-917	248	117	czech	czech	PROPN
ap-917	248	118	technical	technical	PROPN
ap-917	248	119	university	university	PROPN
ap-917	248	120	faculty	faculty	NOUN
ap-917	248	121	of	of	ADP
ap-917	248	122	mechanical	mechanical	ADJ
ap-917	248	123	engineering	engineering	NOUN
ap-917	248	124	technická	technická	NOUN
ap-917	248	125	4	4	NUM
ap-917	248	126	166	166	NUM
ap-917	248	127	07	07	NUM
ap-917	248	128	prague	prague	NOUN
ap-917	248	129	6	6	NUM
ap-917	248	130	,	,	PUNCT
ap-917	248	131	czech	czech	PROPN
ap-917	248	132	republic	republic	PROPN
ap-917	248	133	otomar	otomar	PROPN
ap-917	248	134	kittnar	kittnar	PROPN
ap-917	248	135	,	,	PUNCT
ap-917	248	136	md	md	PROPN
ap-917	248	137	,	,	PUNCT
ap-917	248	138	ph.d	ph.d	PROPN
ap-917	249	1	.	.	PUNCT
ap-917	249	2	phone	phone	NOUN
ap-917	249	3	:	:	PUNCT
ap-917	249	4	+420224912903	+420224912903	NOUN
ap-917	250	1	e	e	NOUN
ap-917	250	2	-	-	NOUN
ap-917	250	3	mail	mail	NOUN
ap-917	250	4	:	:	PUNCT
ap-917	250	5	otomar.kittnar@	otomar.kittnar@	PROPN
ap-917	250	6	lf1.cuni.cz	lf1.cuni.cz	PROPN
ap-917	250	7	institute	institute	PROPN
ap-917	250	8	of	of	ADP
ap-917	250	9	physiology	physiology	PROPN
ap-917	250	10	charles	charles	PROPN
ap-917	250	11	university	university	PROPN
ap-917	250	12	first	first	ADJ
ap-917	250	13	faculty	faculty	NOUN
ap-917	250	14	of	of	ADP
ap-917	250	15	medicine	medicine	NOUN
ap-917	250	16	albertov	albertov	PROPN
ap-917	250	17	5	5	NUM
ap-917	250	18	128	128	NUM
ap-917	250	19	00	00	NUM
ap-917	250	20	prague	prague	PROPN
ap-917	250	21	2	2	NUM
ap-917	250	22	,	,	PUNCT
ap-917	250	23	czech	czech	PROPN
ap-917	250	24	republic	republic	NOUN
ap-917	250	25	10	10	NUM
ap-917	250	26	©	©	PROPN
ap-917	250	27	czech	czech	PROPN
ap-917	250	28	technical	technical	PROPN
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ap-917	250	30	publishing	publishing	NOUN
ap-917	250	31	house	house	NOUN
ap-917	250	32	http://ctn.cvut.cz/ap/	http://ctn.cvut.cz/ap/	PROPN
ap-917	250	33	acta	acta	PROPN
ap-917	250	34	polytechnica	polytechnica	PROPN
ap-917	250	35	vol	vol	NOUN
ap-917	250	36	.	.	PUNCT
ap-917	251	1	48	48	NUM
ap-917	251	2	no	no	NOUN
ap-917	251	3	.	.	PUNCT
ap-917	252	1	1/2008	1/2008	NUM
ap-917	252	2	<	<	X
ap-917	252	3	<	<	X
ap-917	252	4	/ascii85encodepages	/ascii85encodepage	NOUN
ap-917	252	5	false	false	ADJ
ap-917	252	6	/allowtransparency	/allowtransparency	NOUN
ap-917	252	7	false	false	ADJ
ap-917	252	8	/autopositionepsfiles	/autopositionepsfile	NOUN
ap-917	252	9	true	true	ADJ
ap-917	252	10	/autorotatepages	/autorotatepage	NOUN
ap-917	252	11	/none	/none	PUNCT
ap-917	252	12	/binding	/binding	PUNCT
ap-917	252	13	/left	/left	ADJ
ap-917	253	1	/calgrayprofile	/calgrayprofile	VERB
ap-917	253	2	(	(	PUNCT
ap-917	253	3	dot	dot	NOUN
ap-917	253	4	gain	gain	NOUN
ap-917	253	5	20	20	NUM
ap-917	253	6	%	%	NOUN
ap-917	253	7	)	)	PUNCT
ap-917	253	8	/calrgbprofile	/calrgbprofile	PUNCT
ap-917	254	1	(	(	PUNCT
ap-917	254	2	srgb	srgb	PROPN
ap-917	254	3	iec61966	iec61966	NOUN
ap-917	254	4	-	-	PUNCT
ap-917	254	5	2.1	2.1	NUM
ap-917	254	6	)	)	PUNCT
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ap-917	255	1	(	(	PUNCT
ap-917	255	2	u.s	u.s	PROPN
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ap-917	255	4	web	web	NOUN
ap-917	255	5	coated	coat	VERB
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ap-917	255	7	v2	v2	NOUN
ap-917	255	8	)	)	PUNCT
ap-917	255	9	/srgbprofile	/srgbprofile	PUNCT
ap-917	255	10	(	(	PUNCT
ap-917	255	11	srgb	srgb	PROPN
ap-917	255	12	iec61966	iec61966	NOUN
ap-917	255	13	-	-	PUNCT
ap-917	255	14	2.1	2.1	NUM
ap-917	255	15	)	)	PUNCT
ap-917	255	16	/cannotembedfontpolicy	/cannotembedfontpolicy	PUNCT
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ap-917	256	2	/compatibilitylevel	/compatibilitylevel	NOUN
ap-917	257	1	1.4	1.4	NUM
ap-917	257	2	/compressobjects	/compressobject	NOUN
ap-917	257	3	/tags	/tag	VERB
ap-917	257	4	/compresspages	/compresspage	NOUN
ap-917	257	5	true	true	ADJ
ap-917	257	6	/convertimagestoindexed	/convertimagestoindexed	ADJ
ap-917	257	7	true	true	ADJ
ap-917	257	8	/passthroughjpegimages	/passthroughjpegimage	NOUN
ap-917	257	9	true	true	ADJ
ap-917	257	10	/createjobticket	/createjobticket	NOUN
ap-917	257	11	false	false	ADJ
ap-917	257	12	/defaultrenderingintent	/defaultrenderingintent	NOUN
ap-917	257	13	/default	/default	PUNCT
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ap-917	257	15	true	true	ADJ
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ap-917	258	1	0.0000	0.0000	NUM
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ap-917	260	1	false	false	ADJ
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ap-917	260	9	true	true	ADJ
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ap-917	260	11	0	0	NUM
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ap-917	260	14	/endpage	/endpage	NOUN
ap-917	260	15	-1	-1	NOUN
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ap-917	260	17	1048576	1048576	NUM
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ap-917	260	19	false	false	ADJ
ap-917	260	20	/maxsubsetpct	/maxsubsetpct	ADJ
ap-917	260	21	100	100	NUM
ap-917	260	22	/optimize	/optimize	NOUN
ap-917	260	23	true	true	ADJ
ap-917	260	24	/opm	/opm	NOUN
ap-917	260	25	1	1	NUM
ap-917	260	26	/parsedsccomments	/parsedsccomment	NOUN
ap-917	260	27	true	true	ADJ
ap-917	260	28	/parsedsccommentsfordocinfo	/parsedsccommentsfordocinfo	VERB
ap-917	260	29	true	true	ADJ
ap-917	260	30	/preservecopypage	/preservecopypage	NOUN
ap-917	260	31	true	true	ADJ
ap-917	260	32	/preservedicmykvalues	/preservedicmykvalue	NOUN
ap-917	260	33	true	true	ADJ
ap-917	260	34	/preserveepsinfo	/preserveepsinfo	NOUN
ap-917	260	35	true	true	ADJ
ap-917	260	36	/preserveflatness	/preserveflatness	NOUN
ap-917	260	37	true	true	ADJ
ap-917	260	38	/preservehalftoneinfo	/preservehalftoneinfo	PUNCT
ap-917	260	39	false	false	ADJ
ap-917	260	40	/preserveopicomments	/preserveopicomment	NOUN
ap-917	260	41	true	true	ADJ
ap-917	260	42	/preserveoverprintsettings	/preserveoverprintsetting	NOUN
ap-917	260	43	true	true	ADJ
ap-917	260	44	/startpage	/startpage	NOUN
ap-917	260	45	1	1	NUM
ap-917	260	46	/subsetfonts	/subsetfont	NOUN
ap-917	260	47	true	true	ADJ
ap-917	260	48	/transferfunctioninfo	/transferfunctioninfo	PUNCT
ap-917	260	49	/apply	/apply	PUNCT
ap-917	260	50	/ucrandbginfo	/ucrandbginfo	PUNCT
ap-917	261	1	/preserve	/preserve	NOUN
ap-917	261	2	/useprologue	/useprologue	NOUN
ap-917	261	3	false	false	ADJ
ap-917	261	4	/colorsettingsfile	/colorsettingsfile	NOUN
ap-917	261	5	(	(	PUNCT
ap-917	261	6	)	)	PUNCT
ap-917	261	7	/alwaysembed	/alwaysembe	VERB
ap-917	261	8	[	[	PUNCT
ap-917	261	9	true	true	ADJ
ap-917	261	10	]	]	PUNCT
ap-917	261	11	/neverembed	/neverembed	PUNCT
ap-917	262	1	[	[	PUNCT
ap-917	262	2	true	true	ADJ
ap-917	262	3	]	]	PUNCT
ap-917	262	4	/antialiascolorimages	/antialiascolorimages	X
ap-917	262	5	false	false	ADJ
ap-917	262	6	/cropcolorimages	/cropcolorimages	PUNCT
ap-917	262	7	true	true	ADJ
ap-917	262	8	/colorimageminresolution	/colorimageminresolution	PUNCT
ap-917	262	9	300	300	NUM
ap-917	262	10	/colorimageminresolutionpolicy	/colorimageminresolutionpolicy	NOUN
ap-917	262	11	/ok	/ok	ADJ
ap-917	263	1	/downsamplecolorimages	/downsamplecolorimage	VERB
ap-917	264	1	true	true	ADJ
ap-917	264	2	/colorimagedownsampletype	/colorimagedownsampletype	PUNCT
ap-917	264	3	/bicubic	/bicubic	NOUN
ap-917	264	4	/colorimageresolution	/colorimageresolution	NOUN
ap-917	265	1	300	300	NUM
ap-917	265	2	/colorimagedepth	/colorimagedepth	PRON
ap-917	265	3	-1	-1	INTJ
ap-917	265	4	/colorimagemindownsampledepth	/colorimagemindownsampledepth	SYM
ap-917	265	5	1	1	NUM
ap-917	265	6	/colorimagedownsamplethreshold	/colorimagedownsamplethreshold	SYM
ap-917	265	7	1.50000	1.50000	NUM
ap-917	265	8	/encodecolorimages	/encodecolorimage	NOUN
ap-917	265	9	true	true	ADJ
ap-917	265	10	/colorimagefilter	/colorimagefilter	PUNCT
ap-917	265	11	/dctencode	/dctencode	PUNCT
ap-917	266	1	/autofiltercolorimages	/autofiltercolorimage	NOUN
ap-917	266	2	true	true	ADJ
ap-917	266	3	/colorimageautofilterstrategy	/colorimageautofilterstrategy	PUNCT
ap-917	266	4	/jpeg	/jpeg	PUNCT
ap-917	266	5	/coloracsimagedict	/coloracsimagedict	PUNCT
ap-917	267	1	<	<	X
ap-917	267	2	<	<	X
ap-917	267	3	/qfactor	/qfactor	NOUN
ap-917	267	4	0.15	0.15	NUM
ap-917	267	5	/hsamples	/hsample	NOUN
ap-917	268	1	[	[	X
ap-917	268	2	1	1	NUM
ap-917	268	3	1	1	NUM
ap-917	268	4	1	1	NUM
ap-917	268	5	1	1	NUM
ap-917	268	6	]	]	PUNCT
ap-917	268	7	/vsamples	/vsample	NOUN
ap-917	269	1	[	[	X
ap-917	269	2	1	1	NUM
ap-917	269	3	1	1	NUM
ap-917	269	4	1	1	NUM
ap-917	269	5	1	1	NUM
ap-917	269	6	]	]	PUNCT
ap-917	269	7	>	>	PUNCT
ap-917	269	8	>	>	X
ap-917	269	9	/colorimagedict	/colorimagedict	PUNCT
ap-917	270	1	<	<	X
ap-917	270	2	<	<	X
ap-917	270	3	/qfactor	/qfactor	NOUN
ap-917	270	4	0.15	0.15	NUM
ap-917	270	5	/hsamples	/hsample	NOUN
ap-917	271	1	[	[	X
ap-917	271	2	1	1	NUM
ap-917	271	3	1	1	NUM
ap-917	271	4	1	1	NUM
ap-917	271	5	1	1	NUM
ap-917	271	6	]	]	PUNCT
ap-917	271	7	/vsamples	/vsample	NOUN
ap-917	272	1	[	[	X
ap-917	272	2	1	1	NUM
ap-917	272	3	1	1	NUM
ap-917	272	4	1	1	NUM
ap-917	272	5	1	1	NUM
ap-917	272	6	]	]	PUNCT
ap-917	272	7	>	>	PUNCT
ap-917	272	8	>	>	X
ap-917	272	9	/jpeg2000coloracsimagedict	/jpeg2000coloracsimagedict	PUNCT
ap-917	273	1	<	<	X
ap-917	273	2	<	<	X
ap-917	273	3	/tilewidth	/tilewidth	PUNCT
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ap-917	273	5	/tileheight	/tileheight	NUM
ap-917	273	6	256	256	NUM
ap-917	273	7	/quality	/quality	NOUN
ap-917	273	8	30	30	NUM
ap-917	273	9	>	>	PUNCT
ap-917	273	10	>	>	X
ap-917	273	11	/jpeg2000colorimagedict	/jpeg2000colorimagedict	PUNCT
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ap-917	273	13	<	<	X
ap-917	273	14	/tilewidth	/tilewidth	PUNCT
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ap-917	273	18	/quality	/quality	NOUN
ap-917	273	19	30	30	NUM
ap-917	273	20	>	>	PUNCT
ap-917	273	21	>	>	X
ap-917	273	22	/antialiasgrayimages	/antialiasgrayimages	X
ap-917	273	23	false	false	ADJ
ap-917	273	24	/cropgrayimages	/cropgrayimage	NOUN
ap-917	273	25	true	true	ADJ
ap-917	273	26	/grayimageminresolution	/grayimageminresolution	ADV
ap-917	273	27	300	300	NUM
ap-917	273	28	/grayimageminresolutionpolicy	/grayimageminresolutionpolicy	NOUN
ap-917	273	29	/ok	/ok	ADJ
ap-917	273	30	/downsamplegrayimages	/downsamplegrayimages	PUNCT
ap-917	274	1	true	true	ADJ
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ap-917	274	3	/bicubic	/bicubic	NOUN
ap-917	274	4	/grayimageresolution	/grayimageresolution	NOUN
ap-917	274	5	300	300	NUM
ap-917	274	6	/grayimagedepth	/grayimagedepth	PUNCT
ap-917	274	7	-1	-1	PUNCT
ap-917	274	8	/grayimagemindownsampledepth	/grayimagemindownsampledepth	PUNCT
ap-917	275	1	2	2	NUM
ap-917	275	2	/grayimagedownsamplethreshold	/grayimagedownsamplethreshold	NUM
ap-917	275	3	1.50000	1.50000	NUM
ap-917	275	4	/encodegrayimages	/encodegrayimage	NOUN
ap-917	275	5	true	true	ADJ
ap-917	275	6	/grayimagefilter	/grayimagefilter	NOUN
ap-917	275	7	/dctencode	/dctencode	PUNCT
ap-917	276	1	/autofiltergrayimages	/autofiltergrayimages	VERB
ap-917	276	2	true	true	ADJ
ap-917	276	3	/grayimageautofilterstrategy	/grayimageautofilterstrategy	INTJ
ap-917	276	4	/jpeg	/jpeg	PUNCT
ap-917	276	5	/grayacsimagedict	/grayacsimagedict	PUNCT
ap-917	277	1	<	<	X
ap-917	277	2	<	<	X
ap-917	277	3	/qfactor	/qfactor	NOUN
ap-917	277	4	0.15	0.15	NUM
ap-917	277	5	/hsamples	/hsample	NOUN
ap-917	278	1	[	[	X
ap-917	278	2	1	1	NUM
ap-917	278	3	1	1	NUM
ap-917	278	4	1	1	NUM
ap-917	278	5	1	1	NUM
ap-917	278	6	]	]	PUNCT
ap-917	278	7	/vsamples	/vsample	NOUN
ap-917	279	1	[	[	X
ap-917	279	2	1	1	NUM
ap-917	279	3	1	1	NUM
ap-917	279	4	1	1	NUM
ap-917	279	5	1	1	NUM
ap-917	279	6	]	]	PUNCT
ap-917	279	7	>	>	PUNCT
ap-917	279	8	>	>	X
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ap-917	280	2	<	<	X
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ap-917	280	5	/hsamples	/hsample	NOUN
ap-917	281	1	[	[	X
ap-917	281	2	1	1	NUM
ap-917	281	3	1	1	NUM
ap-917	281	4	1	1	NUM
ap-917	281	5	1	1	NUM
ap-917	281	6	]	]	PUNCT
ap-917	281	7	/vsamples	/vsample	NOUN
ap-917	282	1	[	[	X
ap-917	282	2	1	1	NUM
ap-917	282	3	1	1	NUM
ap-917	282	4	1	1	NUM
ap-917	282	5	1	1	NUM
ap-917	282	6	]	]	PUNCT
ap-917	282	7	>	>	X
ap-917	282	8	>	>	X
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ap-917	283	1	<	<	X
ap-917	283	2	<	<	X
ap-917	283	3	/tilewidth	/tilewidth	PUNCT
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ap-917	283	6	256	256	NUM
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ap-917	283	9	>	>	PUNCT
ap-917	283	10	>	>	X
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ap-917	283	20	>	>	PUNCT
ap-917	283	21	>	>	X
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ap-917	283	23	false	false	ADJ
ap-917	283	24	/cropmonoimages	/cropmonoimage	NOUN
ap-917	283	25	true	true	ADJ
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ap-917	283	27	1200	1200	NUM
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ap-917	284	1	/ok	/ok	PROPN
ap-917	284	2	/downsamplemonoimages	/downsamplemonoimage	VERB
ap-917	285	1	true	true	ADJ
ap-917	285	2	/monoimagedownsampletype	/monoimagedownsampletype	PUNCT
ap-917	285	3	/bicubic	/bicubic	NOUN
ap-917	285	4	/monoimageresolution	/monoimageresolution	NOUN
ap-917	285	5	1200	1200	NUM
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ap-917	285	7	-1	-1	PUNCT
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ap-917	286	2	1.50000	1.50000	NUM
ap-917	286	3	/encodemonoimages	/encodemonoimage	NOUN
ap-917	286	4	true	true	ADJ
ap-917	286	5	/monoimagefilter	/monoimagefilter	ADP
ap-917	286	6	/ccittfaxencode	/ccittfaxencode	INTJ
ap-917	286	7	/monoimagedict	/monoimagedict	PUNCT
ap-917	287	1	<	<	X
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ap-917	287	3	/k	/k	PUNCT
ap-917	287	4	-1	-1	INTJ
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ap-917	287	6	>	>	X
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ap-917	287	9	/checkcompliance	/checkcompliance	NOUN
ap-917	287	10	[	[	PUNCT
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ap-917	287	20	true	true	ADJ
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ap-917	289	4	(	(	PUNCT
ap-917	289	5	)	)	PUNCT
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ap-917	289	7	(	(	PUNCT
ap-917	289	8	)	)	PUNCT
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ap-917	289	10	(	(	PUNCT
ap-917	289	11	)	)	PUNCT
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ap-917	299	3	>	>	X
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ap-917	299	7	>	>	X
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ap-917	299	11	>	>	X
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ap-917	300	4	adobe	adobe	PROPN
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ap-917	300	6	dokumenata	dokumenata	PROPN
ap-917	300	7	najpogodnijih	najpogodnijih	PROPN
ap-917	300	8	za	za	PROPN
ap-917	300	9	visokokvalitetni	visokokvalitetni	VERB
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ap-917	300	15	postavke	postavke	NOUN
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ap-917	301	2	pdf	pdf	NOUN
ap-917	301	3	dokumenti	dokumenti	PROPN
ap-917	301	4	mogu	mogu	PROPN
ap-917	301	5	se	se	X
ap-917	301	6	otvoriti	otvoriti	PROPN
ap-917	301	7	acrobat	acrobat	PROPN
ap-917	302	1	i	i	PRON
ap-917	302	2	adobe	adobe	PROPN
ap-917	302	3	reader	reader	PROPN
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ap-917	316	15	>	>	X
ap-917	316	16	/enu	/enu	PUNCT
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ap-917	316	19	these	these	DET
ap-917	316	20	settings	setting	NOUN
ap-917	316	21	to	to	PART
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ap-917	316	23	adobe	adobe	PROPN
ap-917	316	24	pdf	pdf	PROPN
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ap-917	316	27	suited	suit	VERB
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ap-917	316	29	high	high	ADJ
ap-917	316	30	-	-	PUNCT
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ap-917	316	32	prepress	prepress	NOUN
ap-917	316	33	printing	printing	NOUN
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ap-917	317	2	pdf	pdf	NOUN
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ap-917	317	4	can	can	AUX
ap-917	317	5	be	be	AUX
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ap-917	317	7	with	with	ADP
ap-917	317	8	acrobat	acrobat	PROPN
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ap-917	317	10	adobe	adobe	PROPN
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ap-917	319	10	)	)	PUNCT
ap-917	319	11	]	]	PUNCT
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ap-917	320	9	/errorcontrol	/errorcontrol	NOUN
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ap-917	321	5	false	false	ADJ
ap-917	321	6	/includenonprinting	/includenonprinting	NOUN
ap-917	321	7	false	false	ADJ
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ap-917	323	3	false	false	ADJ
ap-917	323	4	/omitplacedpdf	/omitplacedpdf	PUNCT
ap-917	323	5	false	false	ADJ
ap-917	323	6	/simulateoverprint	/simulateoverprint	NOUN
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ap-917	325	1	<	<	X
ap-917	325	2	<	<	X
ap-917	325	3	/addbleedmarks	/addbleedmarks	X
ap-917	325	4	false	false	ADJ
ap-917	325	5	/addcolorbars	/addcolorbars	INTJ
ap-917	325	6	false	false	ADJ
ap-917	325	7	/addcropmarks	/addcropmarks	PUNCT
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ap-917	325	9	/addpageinfo	/addpageinfo	INTJ
ap-917	325	10	false	false	ADJ
ap-917	325	11	/addregmarks	/addregmark	NOUN
ap-917	325	12	false	false	ADJ
ap-917	325	13	/convertcolors	/convertcolor	NOUN
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ap-917	327	3	false	false	ADJ
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ap-917	327	7	false	false	ADJ
ap-917	327	8	/includeinteractive	/includeinteractive	ADJ
ap-917	327	9	false	false	ADJ
ap-917	327	10	/includelayers	/includelayer	NOUN
ap-917	327	11	false	false	ADJ
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ap-917	327	13	false	false	ADJ
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ap-917	330	7	)	)	PUNCT
ap-917	330	8	(	(	PUNCT
ap-917	330	9	2.0	2.0	NUM
ap-917	330	10	)	)	PUNCT
ap-917	330	11	]	]	PUNCT
ap-917	331	1	/pdfxoutputintentprofileselector	/pdfxoutputintentprofileselector	INTJ
ap-917	331	2	/documentcmyk	/documentcmyk	PUNCT
ap-917	332	1	/preserveediting	/preserveedite	VERB
ap-917	332	2	true	true	ADJ
ap-917	332	3	/untaggedcmykhandling	/untaggedcmykhandling	NOUN
ap-917	332	4	/leaveuntagged	/leaveuntagge	VERB
ap-917	332	5	/untaggedrgbhandling	/untaggedrgbhandling	NOUN
ap-917	332	6	/usedocumentprofile	/usedocumentprofile	INTJ
ap-917	332	7	/usedocumentbleed	/usedocumentbleed	NOUN
ap-917	333	1	false	false	ADJ
ap-917	333	2	>	>	PUNCT
ap-917	333	3	>	>	X
ap-917	333	4	]	]	PUNCT
ap-917	333	5	>	>	PUNCT
ap-917	333	6	>	>	X
ap-917	333	7	setdistillerparams	setdistillerparam	NOUN
ap-917	334	1	<	<	X
ap-917	334	2	<	<	X
ap-917	334	3	/hwresolution	/hwresolution	NOUN
ap-917	335	1	[	[	X
ap-917	335	2	2400	2400	NUM
ap-917	335	3	2400	2400	NUM
ap-917	335	4	]	]	PUNCT
ap-917	335	5	/pagesize	/pagesize	X
ap-917	336	1	[	[	X
ap-917	336	2	612.000	612.000	NUM
ap-917	336	3	792.000	792.000	NUM
ap-917	336	4	]	]	PUNCT
ap-917	336	5	>	>	PUNCT
ap-917	336	6	>	>	X
ap-917	336	7	setpagedevice	setpagedevice	PROPN