id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
admet-1022	Tsantili-Kakoulidou, Anna; Demopoulos, Vassilis	Drug-like Properties and Fraction Lipophilicity Index as a combined metric 	2021	14	.pdf	application/pdf	5990	340	54	Drugs beyond the drug-like limits Recently, there has been an increased interest in the development of drugs beyond the Rule of five (bRo5), especially in the area of oncology and direct-acting antivirals (DAA) Keywords drug-likeness; oral drugs; Fraction Lipophilicity Index; Rule of 5; Molecular weight; Polar atoms Introduction The role of physicochemical properties in controlling the fate of drug molecules within the organism and their binding to macromolecules has been well documented.	cache/admet-1022.pdf	txt/admet-1022.txt