id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
admet-2541	Verbić, Tatjana; Mandić, Zoran	Special issue devoted to the IAPC-10 Meeting: Joint World Conferences on Physico-Chemical Methods in Drug Discovery and Development and on ADMET and DMPK	2024	2	.pdf	application/pdf	746	25	25	Diego Garcia Jimenez et al. report the full physicochemical characterization of three PROTACs in clinical trials; the paper focuses on the molecular properties essential to drive oral bioavailability within the beyond rule of five (bRo5) drug framework. https://doi.org/10.5599/admet.2541 https://doi.org/10.5599/admet.2541 http://www.pub.iapchem.org/ojs/index.php/admet/index mailto:tatjanad@chem.bg.ac.rs mailto:zmandic@fkit.hr T. Verbić and Z. Mandić ADMET & DMPK 12(5) (2024) 703-704 704 Shan Lu et al. discuss physiologically based pharmacokinetics (PBPK) modelling, coupled with pharmaco- dynamics (PD) simulations, to explore possible factors determining drug nanocrystals' biodistribution and treatment efficacy.	cache/admet-2541.pdf	txt/admet-2541.txt