id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
admet-557	Saini, Neeraj Kumar; Sulochana, Suresh P; Zainuddin, Mohd; Mullangi, Ramesh	Development and validation of a novel method for simultaneous quantification of enzalutamide, darolutamide and their active metabolites in mice dried blood spots using LC-MS/MS: Application to pharmacokinetic study in mice	2018	16	.pdf	application/pdf	6783	294	43	Recovery The efficiency of enzalutamide, N-desmethylenzalutamide, darolutamide, ORM-15341 and the IS extraction from DBS samples was determined by comparing the responses of the analyte extracted from replicate QC samples (n = 6) with the response of analyte from neat standards at equivalent concentrations by liquid extraction process. Matrix effect Matrix effect for enzalutamide, N-desmethylenzalutamide, darolutamide and ORM-15341 was assessed by comparing each analyte mean peak areas at LQC and HQC concentration after with the mean peak areas for post extracted DBS samples spiked with analyte at equivalent concentrations.	cache/admet-557.pdf	txt/admet-557.txt