id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
admet-667	Shaik, Abdul Naveed; Khan, Ansar Ali	Physiologically based pharmacokinetic (PBPK) modeling and simulation in drug discovery and development	2019	3	.pdf	application/pdf	1262	60	40	PBPK models can be used in different phases of drug development including the first in human (FIH) dose prediction from preclinical data. In particular, these regulatory agencies have issued guidance for application and use of PBPK models at various stages of drug development including, investigational new drug applications (INDs), new drug applications (NDAs), biologics license applications (BLAs), or abbreviated new drug applications (ANDAs) etc.	cache/admet-667.pdf	txt/admet-667.txt