id	sid	eid	entity	type
admet-258	1	1	10.5599	CARDINAL
admet-258	1	2	35	CARDINAL
admet-258	1	3	admet &	ORG
admet-258	1	4	4(1	CARDINAL
admet-258	1	5	2016	CARDINAL
admet-258	1	6	35	CARDINAL
admet-258	1	7	10.5599	CARDINAL
admet-258	1	8	issn	PERSON
admet-258	1	9	1848-7718	DATE
admet-258	1	10	jörg berghausen1	PERSON
admet-258	1	11	frank h. seiler2	PERSON
admet-258	1	12	nathalie gobeau1,3	PERSON
admet-258	1	13	bernard faller1 1	PERSON
admet-258	1	14	novartis	ORG
admet-258	1	15	novartis	ORG
admet-258	1	16	ch-4002	ORG
admet-258	1	17	2	CARDINAL
admet-258	1	18	novartis pharma ag	ORG
admet-258	1	19	novartis	ORG
admet-258	1	20	ch-4002	ORG
admet-258	1	21	3	CARDINAL
admet-258	1	22	20	CARDINAL
admet-258	1	23	de pré-bois	PERSON
admet-258	1	24	1215	DATE
admet-258	1	25	geneva 15	FAC
admet-258	2	1	61 69 62335	CARDINAL
admet-258	2	2	november 18, 2015	DATE
admet-258	2	3	march 12, 2016	DATE
admet-258	2	4	march 31	DATE
admet-258	2	5	2016	DATE
admet-258	3	1	fed	ORG
admet-258	6	1	6.8	CARDINAL
admet-258	7	1	nine	CARDINAL
admet-258	7	2	up to 300 mg/kg	QUANTITY
admet-258	12	1	discovery	PRODUCT
admet-258	13	1	kostewicz et al	PERSON
admet-258	14	1	1	CARDINAL
admet-258	15	1	al. admet	ORG
admet-258	15	2	4(1	CARDINAL
admet-258	15	3	2016	CARDINAL
admet-258	15	4	35	CARDINAL
admet-258	15	5	two	CARDINAL
admet-258	23	1	discovery	PRODUCT
admet-258	24	1	2,3	CARDINAL
admet-258	26	1	4	CARDINAL
admet-258	28	1	5	CARDINAL
admet-258	28	2	fassif	ORG
admet-258	29	1	6	CARDINAL
admet-258	31	1	12-51 mm	QUANTITY
admet-258	32	1	7	CARDINAL
admet-258	35	1	minipigs	NORP
admet-258	37	1	10	CARDINAL
admet-258	39	1	11	CARDINAL
admet-258	41	1	gao et al	PERSON
admet-258	42	1	6	CARDINAL
admet-258	42	2	4(1	CARDINAL
admet-258	42	3	2016	CARDINAL
admet-258	42	4	35	CARDINAL
admet-258	42	5	10.5599	CARDINAL
admet-258	42	6	37	DATE
admet-258	44	1	discovery	PRODUCT
admet-258	46	1	6.8	CARDINAL
admet-258	46	2	fassif	ORG
admet-258	47	1	6	CARDINAL
admet-258	48	1	log p	ORG
admet-258	48	2	12	CARDINAL
admet-258	50	1	13	CARDINAL
admet-258	51	1	three	CARDINAL
admet-258	51	2	6.8	CARDINAL
admet-258	52	1	about 1.5 mg	TIME
admet-258	53	1	20 to 24 hours	TIME
admet-258	53	2	15 min at 2000	TIME
admet-258	53	3	1200	CARDINAL
admet-258	54	1	t3	ORG
admet-258	54	2	sirius instruments ltd.	ORG
admet-258	56	1	t3	ORG
admet-258	56	2	sirius instruments ltd.	ORG
admet-258	57	1	merck kgaa	ORG
admet-258	57	2	6.8	CARDINAL
admet-258	57	3	0.1	CARDINAL
admet-258	57	4	di-sodium	PERSON
admet-258	59	1	14	CARDINAL
admet-258	60	1	first	ORDINAL
admet-258	60	2	400 ml	QUANTITY
admet-258	60	3	1 ml	QUANTITY
admet-258	61	1	30 min	TIME
admet-258	61	2	another two hours	TIME
admet-258	62	1	500 ml	QUANTITY
admet-258	63	1	overnight	TIME
admet-258	63	2	6.5	CARDINAL
admet-258	63	3	1	CARDINAL
admet-258	64	1	15	CARDINAL
admet-258	65	1	14	CARDINAL
admet-258	66	1	11	CARDINAL
admet-258	68	1	1	CARDINAL
admet-258	69	1	al. admet	ORG
admet-258	69	2	4(1	CARDINAL
admet-258	69	3	2016	CARDINAL
admet-258	69	4	35	CARDINAL
admet-258	69	5	1	CARDINAL
admet-258	69	6	6.0 6.5	CARDINAL
admet-258	69	7	15.2 10	CARDINAL
admet-258	69	8	42 54.3	CARDINAL
admet-258	69	9	480 180	CARDINAL
admet-258	69	10	25 3	DATE
admet-258	70	1	5.16 0.2	CARDINAL
admet-258	71	1	fed	ORG
admet-258	72	1	6.0	CARDINAL
admet-258	72	2	2,16,17	CARDINAL
admet-258	73	1	5.0	CARDINAL
admet-258	73	2	7.1	CARDINAL
admet-258	79	1	18	CARDINAL
admet-258	80	1	19	CARDINAL
admet-258	81	1	17	CARDINAL
admet-258	83	1	19	CARDINAL
admet-258	85	1	14	CARDINAL
admet-258	86	1	2	CARDINAL
admet-258	86	2	100 ml	QUANTITY
admet-258	87	1	5.00 537.7 269	QUANTITY
admet-258	87	2	18.70 58.0 108	QUANTITY
admet-258	87	3	5.16	CARDINAL
admet-258	87	4	775.0 400	QUANTITY
admet-258	87	5	29.86	CARDINAL
admet-258	87	6	116.1 347	CARDINAL
admet-258	89	1	0.26	CARDINAL
admet-258	89	2	12.50	CARDINAL
admet-258	89	3	430.6 538	CARDINAL
admet-258	89	4	7.50	CARDINAL
admet-258	89	5	414.6 311	QUANTITY
admet-258	89	6	1.67	CARDINAL
admet-258	89	7	60	CARDINAL
admet-258	89	8	admet &	ORG
admet-258	89	9	4(1	CARDINAL
admet-258	89	10	2016	CARDINAL
admet-258	89	11	35	CARDINAL
admet-258	89	12	10.5599	CARDINAL
admet-258	89	13	39	CARDINAL
admet-258	89	14	100 ml	QUANTITY
admet-258	89	15	2	CARDINAL
admet-258	90	1	50 ml	QUANTITY
admet-258	91	1	30 min	TIME
admet-258	92	1	about 5-10 min	CARDINAL
admet-258	92	2	overnight	TIME
admet-258	94	1	40 ml	QUANTITY
admet-258	94	2	around 2.2	CARDINAL
admet-258	95	1	6.0	CARDINAL
admet-258	95	2	1 m	QUANTITY
admet-258	98	1	up to 100 ml	QUANTITY
admet-258	99	1	kibron	ORG
admet-258	99	2	kibron inc.	ORG
admet-258	99	3	helsinki	PERSON
admet-258	100	1	42.8	CARDINAL
admet-258	101	1	pbpk	PERSON
admet-258	101	2	lancaster	GPE
admet-258	101	3	8.6	CARDINAL
admet-258	106	1	pampa	GPE
admet-258	107	1	first	ORDINAL
admet-258	108	1	83	CARDINAL
admet-258	109	1	1	CARDINAL
admet-258	110	1	two	CARDINAL
admet-258	111	1	250	CARDINAL
admet-258	115	1	fed	ORG
admet-258	116	1	fed	ORG
admet-258	119	1	6.1	CARDINAL
admet-258	120	1	zero	CARDINAL
admet-258	120	2	1	CARDINAL
admet-258	120	3	4log3	CARDINAL
admet-258	120	4	10	CARDINAL
admet-258	121	1	1	CARDINAL
admet-258	121	2	al. admet	ORG
admet-258	121	3	4(1	CARDINAL
admet-258	121	4	2016	CARDINAL
admet-258	121	5	35	CARDINAL
admet-258	121	6	53 40	CARDINAL
admet-258	121	7	1	CARDINAL
admet-258	121	8	log pampa	ORG
admet-258	123	1	first	ORDINAL
admet-258	125	1	12	CARDINAL
admet-258	125	2	germani et al	PERSON
admet-258	126	1	21	CARDINAL
admet-258	126	2	jones et al	PERSON
admet-258	127	1	22	CARDINAL
admet-258	128	1	2	CARDINAL
admet-258	129	1	4(1	CARDINAL
admet-258	129	2	2016	CARDINAL
admet-258	129	3	35	CARDINAL
admet-258	129	4	10.5599	CARDINAL
admet-258	129	5	41	CARDINAL
admet-258	129	6	first	ORDINAL
admet-258	129	7	first	ORDINAL
admet-258	129	8	2	CARDINAL
admet-258	129	9	first	ORDINAL
admet-258	129	10	61	CARDINAL
admet-258	131	1	7	CARDINAL
admet-258	131	2	m	ORG
admet-258	134	1	sprague	GPE
admet-258	134	2	charles river wiga	ORG
admet-258	134	3	germany	GPE
admet-258	135	1	canton	GPE
admet-258	135	2	switzerland	GPE
admet-258	136	1	six to four days	DATE
admet-258	136	2	first	ORDINAL
admet-258	137	1	270-330	CARDINAL
admet-258	138	1	harvard	ORG
admet-258	139	1	10 µg kg-1	DATE
admet-258	139	2	s.c.	GPE
admet-258	141	1	i.v.	PERSON
admet-258	142	1	p.o.	GPE
admet-258	142	2	two	CARDINAL
admet-258	144	1	200	CARDINAL
admet-258	145	1	approximately 50	CARDINAL
admet-258	146	1	30	CARDINAL
admet-258	146	2	200	CARDINAL
admet-258	146	3	4 °	QUANTITY
admet-258	148	1	200	CARDINAL
admet-258	148	2	200	CARDINAL
admet-258	148	3	0.1 %	PERCENT
admet-258	149	1	al. admet	ORG
admet-258	149	2	4(1	CARDINAL
admet-258	149	3	2016	CARDINAL
admet-258	149	4	35	CARDINAL
admet-258	150	1	gao et al	PERSON
admet-258	151	1	6	CARDINAL
admet-258	152	1	four	CARDINAL
admet-258	153	1	gao et al	PERSON
admet-258	155	1	gao et al	PERSON
admet-258	155	2	0.8657	CARDINAL
admet-258	155	3	h/100 g.	PERSON
admet-258	155	4	0.033 ml/min/kg	QUANTITY
admet-258	155	5	70 ml	QUANTITY
admet-258	156	1	0.25	CARDINAL
admet-258	156	2	0.2	CARDINAL
admet-258	156	3	4.5	CARDINAL
admet-258	156	4	8	CARDINAL
admet-258	159	1	1.5	CARDINAL
admet-258	159	2	1.9	CARDINAL
admet-258	159	3	5.8	CARDINAL
admet-258	159	4	2.9	CARDINAL
admet-258	161	1	3	CARDINAL
admet-258	162	1	2	CARDINAL
admet-258	166	1	6.8	CARDINAL
admet-258	166	2	3	CARDINAL
admet-258	166	3	3	CARDINAL
admet-258	167	1	6.8	CARDINAL
admet-258	167	2	6.8	CARDINAL
admet-258	167	3	0.001 0.0041 0.105	QUANTITY
admet-258	167	4	0.004 0.0001	CARDINAL
admet-258	168	1	0.031	CARDINAL
admet-258	168	2	0.05 0.14 0.881	MONEY
admet-258	168	3	0.003	CARDINAL
admet-258	168	4	0.193	CARDINAL
admet-258	168	5	0.0002 0.0005 0.01	MONEY
admet-258	168	6	0.0025 0.002 0.015	MONEY
admet-258	168	7	6.8	CARDINAL
admet-258	169	1	two	CARDINAL
admet-258	169	2	4(1	CARDINAL
admet-258	169	3	2016	CARDINAL
admet-258	169	4	35	CARDINAL
admet-258	169	5	10.5599	CARDINAL
admet-258	169	6	43	DATE
admet-258	169	7	7-fold	CARDINAL
admet-258	171	1	bile salt	PERSON
admet-258	173	1	one	CARDINAL
admet-258	173	2	one	CARDINAL
admet-258	173	3	first	ORDINAL
admet-258	176	1	11	CARDINAL
admet-258	178	1	51 mm	QUANTITY
admet-258	178	2	9	CARDINAL
admet-258	180	1	20	CARDINAL
admet-258	180	2	sc sr sc	ORG
admet-258	180	3	2	CARDINAL
admet-258	180	4	scbs	ORG
admet-258	181	1	plog	PERSON
admet-258	181	2	2.23	CARDINAL
admet-258	181	3	3	CARDINAL
admet-258	182	1	4	CARDINAL
admet-258	182	2	10	CARDINAL
admet-258	182	3	50	CARDINAL
admet-258	182	4	100 mm	QUANTITY
admet-258	183	1	6.8	CARDINAL
admet-258	183	2	55.5 mol	QUANTITY
admet-258	184	1	sr	ORG
admet-258	184	2	3	CARDINAL
admet-258	185	1	al. admet	ORG
admet-258	185	2	4(1	CARDINAL
admet-258	185	3	2016	CARDINAL
admet-258	185	4	35	CARDINAL
admet-258	185	5	sr	ORG
admet-258	185	6	log p	ORG
admet-258	185	7	log sr	ORG
admet-258	186	1	3	CARDINAL
admet-258	187	1	4	CARDINAL
admet-258	187	2	sr	ORG
admet-258	187	3	more than one	CARDINAL
admet-258	187	4	10	CARDINAL
admet-258	187	5	50	CARDINAL
admet-258	187	6	100 mm	QUANTITY
admet-258	188	1	about 2	CARDINAL
admet-258	188	2	sr	ORG
admet-258	190	1	4	CARDINAL
admet-258	190	2	4	CARDINAL
admet-258	190	3	10	CARDINAL
admet-258	190	4	100 mm	QUANTITY
admet-258	191	1	6.8	CARDINAL
admet-258	192	1	sr10	PRODUCT
admet-258	192	2	sr50	PRODUCT
admet-258	192	3	1	CARDINAL
admet-258	193	1	sr10	PRODUCT
admet-258	193	2	sr50 log sr100 cpd	PRODUCT
admet-258	193	3	1 529.5	CARDINAL
admet-258	193	4	5.2 5.4b	CARDINAL
admet-258	193	5	17.78	CARDINAL
admet-258	193	6	666.9	CARDINAL
admet-258	193	7	2	CARDINAL
admet-258	193	8	3.2	CARDINAL
admet-258	193	9	0.022 0.04 0.26 0.34	QUANTITY
admet-258	193	10	3	CARDINAL
admet-258	193	11	0.0054 0.42 3.95	MONEY
admet-258	193	12	4 558.2	CARDINAL
admet-258	193	13	9.1b	CARDINAL
admet-258	193	14	4.1b	CARDINAL
admet-258	193	15	0.001 0.7 4.12	QUANTITY
admet-258	193	16	5	CARDINAL
admet-258	193	17	577.8	CARDINAL
admet-258	193	18	4.9	CARDINAL
admet-258	193	19	3.9b	CARDINAL
admet-258	193	20	0.3202 10.8 11.02	MONEY
admet-258	193	21	11.23	CARDINAL
admet-258	193	22	4.582	CARDINAL
admet-258	193	23	6	CARDINAL
admet-258	193	24	2.6 5.1b	CARDINAL
admet-258	193	25	2.27 4.35	CARDINAL
admet-258	193	26	7	CARDINAL
admet-258	193	27	4.3	CARDINAL
admet-258	193	28	0.001	CARDINAL
admet-258	193	29	0.001 0.15 0.34	MONEY
admet-258	193	30	4.907	CARDINAL
admet-258	193	31	8	CARDINAL
admet-258	193	32	0.0066 0.01	MONEY
admet-258	193	33	3.225 2.924	CARDINAL
admet-258	193	34	9	CARDINAL
admet-258	193	35	3.8b	CARDINAL
admet-258	193	36	0.0014 0.03	QUANTITY
admet-258	193	37	6.001 5.875	CARDINAL
admet-258	193	38	10	CARDINAL
admet-258	193	39	313.4 3.7	CARDINAL
admet-258	193	40	0.16	CARDINAL
admet-258	193	41	3.686	CARDINAL
admet-258	193	42	11	CARDINAL
admet-258	193	43	0.14 0.46 0.51	QUANTITY
admet-258	193	44	0.63	CARDINAL
admet-258	194	1	lo g s	PERSON
admet-258	195	1	3	CARDINAL
admet-258	196	1	10 mm	QUANTITY
admet-258	196	2	sr10	PRODUCT
admet-258	196	3	50 mm	QUANTITY
admet-258	196	4	sr50	PRODUCT
admet-258	196	5	100 mm	QUANTITY
admet-258	196	6	100	CARDINAL
admet-258	197	1	2	CARDINAL
admet-258	198	1	4(1	CARDINAL
admet-258	198	2	2016	CARDINAL
admet-258	198	3	35	CARDINAL
admet-258	198	4	10.5599	CARDINAL
admet-258	198	5	45	CARDINAL
admet-258	199	1	log p	ORG
admet-258	200	1	2	CARDINAL
admet-258	202	1	pbpk	PERSON
admet-258	208	1	5	CARDINAL
admet-258	210	1	five	CARDINAL
admet-258	211	1	first	ORDINAL
admet-258	213	1	4	CARDINAL
admet-258	214	1	sif	PERSON
admet-258	215	1	sif medium	PERSON
admet-258	216	1	gao et al.[6	ORG
admet-258	217	1	5	CARDINAL
admet-258	219	1	first	ORDINAL
admet-258	221	1	vc	PERSON
admet-258	222	1	only two	CARDINAL
admet-258	222	2	vc	PERSON
admet-258	223	1	first	ORDINAL
admet-258	223	2	er% pka log pampa	ORG
admet-258	223	3	l/h	ORG
admet-258	223	4	kg vc	PERSON
admet-258	223	5	77 3.8	CARDINAL
admet-258	223	6	1.7 0.42 0.38	QUANTITY
admet-258	223	7	0.15	CARDINAL
admet-258	223	8	1.67	CARDINAL
admet-258	223	9	28 5.4	CARDINAL
admet-258	223	10	3.7 1.10 3.28	CARDINAL
admet-258	223	11	4.58	CARDINAL
admet-258	224	1	92	CARDINAL
admet-258	225	1	3.48 2.77	CARDINAL
admet-258	225	2	0.95	CARDINAL
admet-258	225	3	1.74	CARDINAL
admet-258	225	4	25 4.7	CARDINAL
admet-258	225	5	-3.6	ORG
admet-258	225	6	3.50	CARDINAL
admet-258	225	7	17.62	CARDINAL
admet-258	225	8	56 2.7	DATE
admet-258	225	9	4.2 0.42 0.88	QUANTITY
admet-258	225	10	2.19	CARDINAL
admet-258	225	11	67	CARDINAL
admet-258	225	12	0.47	CARDINAL
admet-258	225	13	55 3.4	CARDINAL
admet-258	225	14	3.9	CARDINAL
admet-258	225	15	4.50	CARDINAL
admet-258	225	16	0.80	CARDINAL
admet-258	225	17	38 3.5	CARDINAL
admet-258	225	18	5.3 1.34 3.74	CARDINAL
admet-258	225	19	7.19	CARDINAL
admet-258	225	20	37 1.7	CARDINAL
admet-258	225	21	2.8 5.19 2.57	CARDINAL
admet-258	225	22	0.55	CARDINAL
admet-258	225	23	al. admet	ORG
admet-258	225	24	4(1	CARDINAL
admet-258	225	25	2016	CARDINAL
admet-258	225	26	35	CARDINAL
admet-258	225	27	6 to 9	CARDINAL
admet-258	227	1	pbpk	PERSON
admet-258	227	2	p.o.	GPE
admet-258	228	1	6	CARDINAL
admet-258	228	2	7	CARDINAL
admet-258	229	1	3	CARDINAL
admet-258	231	1	6	CARDINAL
admet-258	232	1	pbpk	PERSON
admet-258	232	2	g	GPE
admet-258	233	1	fassif	ORG
admet-258	233	2	fassif	ORG
admet-258	235	1	obs.	ORG
admet-258	237	1	10	CARDINAL
admet-258	239	1	3	CARDINAL
admet-258	239	2	0.040 0.238	CARDINAL
admet-258	240	1	obs	CARDINAL
admet-258	241	1	1.7246	MONEY
admet-258	241	2	3	CARDINAL
admet-258	243	1	0.3358	MONEY
admet-258	244	1	10 2.211 0.069 0.071	QUANTITY
admet-258	244	2	1.517	MONEY
admet-258	245	1	10	CARDINAL
admet-258	245	2	2.743	MONEY
admet-258	245	3	2.308	MONEY
admet-258	246	1	3	CARDINAL
admet-258	246	2	0.073	PRODUCT
admet-258	247	1	3.650	CARDINAL
admet-258	248	1	0.0085 0.0085	MONEY
admet-258	248	2	3	CARDINAL
admet-258	249	1	0.1964 0.1429	MONEY
admet-258	249	2	1.107	MONEY
admet-258	249	3	6	CARDINAL
admet-258	249	4	7	CARDINAL
admet-258	249	5	4	CARDINAL
admet-258	252	1	ten	CARDINAL
admet-258	252	2	the 10 mg/kg	PRODUCT
admet-258	253	1	4(1	CARDINAL
admet-258	253	2	2016	CARDINAL
admet-258	253	3	35	CARDINAL
admet-258	253	4	10.5599	CARDINAL
admet-258	253	5	47	CARDINAL
admet-258	253	6	7	CARDINAL
admet-258	253	7	pbpk	PERSON
admet-258	253	8	g	GPE
admet-258	254	1	fassif	ORG
admet-258	254	2	fassif	ORG
admet-258	256	1	obs.	ORG
admet-258	258	1	10	CARDINAL
admet-258	258	2	1.08	MONEY
admet-258	258	3	5.05	CARDINAL
admet-258	259	1	obs 0.0113	ORG
admet-258	259	2	3 1.928	CARDINAL
admet-258	259	3	0.414 1.867	CARDINAL
admet-258	261	1	0.9684	MONEY
admet-258	261	2	3	CARDINAL
admet-258	261	3	0.071	CARDINAL
admet-258	263	1	0.3060	MONEY
admet-258	263	2	3	CARDINAL
admet-258	263	3	1.154	MONEY
admet-258	263	4	1.802	CARDINAL
admet-258	264	1	9.351 9.335	CARDINAL
admet-258	265	1	obs 0.0287	ORG
admet-258	266	1	0.3536	MONEY
admet-258	266	2	10	CARDINAL
admet-258	266	3	13.4 7.812	MONEY
admet-258	266	4	7.812	MONEY
admet-258	268	1	0.5830 0.5830	MONEY
admet-258	268	2	0.5772	MONEY
admet-258	268	3	3	CARDINAL
admet-258	269	1	1.985	MONEY
admet-258	269	2	3 1.06 0.007	QUANTITY
admet-258	270	1	3	CARDINAL
admet-258	272	1	fassif	ORG
admet-258	273	1	4	CARDINAL
admet-258	274	1	6	CARDINAL
admet-258	274	2	7	CARDINAL
admet-258	275	1	sif	PERSON
admet-258	276	1	at least 3	CARDINAL
admet-258	277	1	2-fold	CARDINAL
admet-258	278	1	one	CARDINAL
admet-258	281	1	al. admet	ORG
admet-258	281	2	4(1	CARDINAL
admet-258	281	3	2016	CARDINAL
admet-258	281	4	35	CARDINAL
admet-258	284	1	g cpd h cpd	ORG
admet-258	287	1	g cpd h cpd	ORG
admet-258	288	1	4	CARDINAL
admet-258	288	2	3 to 10 mg/kg	TIME
admet-258	288	3	p.o.	GPE
admet-258	288	4	p.o.	GPE
admet-258	289	1	pbpk	PERSON
admet-258	289	2	30	CARDINAL
admet-258	289	3	8	CARDINAL
admet-258	289	4	9	CARDINAL
admet-258	290	1	5	CARDINAL
admet-258	291	1	4(1	CARDINAL
admet-258	291	2	2016	CARDINAL
admet-258	291	3	35	CARDINAL
admet-258	291	4	10.5599	CARDINAL
admet-258	291	5	49	CARDINAL
admet-258	291	6	3-fold	CARDINAL
admet-258	291	7	2-fold	CARDINAL
admet-258	294	1	8	CARDINAL
admet-258	295	1	pbpk	PERSON
admet-258	295	2	g	GPE
admet-258	296	1	fassif	ORG
admet-258	296	2	fassif	ORG
admet-258	298	1	obs.	ORG
admet-258	300	1	30	CARDINAL
admet-258	300	2	0.047	CARDINAL
admet-258	301	1	0.0055	CARDINAL
admet-258	301	2	100	CARDINAL
admet-258	301	3	0.127 4.02	CARDINAL
admet-258	302	1	0.2197	MONEY
admet-258	302	2	30	CARDINAL
admet-258	302	3	1.531	MONEY
admet-258	303	1	0.0280 0.0293 0.1518	MONEY
admet-258	303	2	30	CARDINAL
admet-258	303	3	0.491	MONEY
admet-258	304	1	0.8993	MONEY
admet-258	304	2	0.271	MONEY
admet-258	304	3	2.04	CARDINAL
admet-258	306	1	2.2467	MONEY
admet-258	306	2	100	CARDINAL
admet-258	306	3	3.592	CARDINAL
admet-258	306	4	1.227 3.869 4.74	MONEY
admet-258	307	1	100	CARDINAL
admet-258	307	2	17.0 26.3 27.3	QUANTITY
admet-258	307	3	27.4	CARDINAL
admet-258	307	4	27.4	CARDINAL
admet-258	308	1	1.547	CARDINAL
admet-258	308	2	1.524	MONEY
admet-258	308	3	30	CARDINAL
admet-258	309	1	0.0062	CARDINAL
admet-258	309	2	30 to 300 mg/kg	QUANTITY
admet-258	311	1	3 mg/kg	QUANTITY
admet-258	311	2	5	CARDINAL
admet-258	312	1	30 mg/kg	QUANTITY
admet-258	312	2	nearly 10-fold	CARDINAL
admet-258	312	3	sif	PERSON
admet-258	312	4	1.3-fold	CARDINAL
admet-258	313	1	more than five	CARDINAL
admet-258	314	1	first	ORDINAL
admet-258	315	1	nine	CARDINAL
admet-258	316	1	al. admet	ORG
admet-258	316	2	4(1	CARDINAL
admet-258	316	3	2016	CARDINAL
admet-258	316	4	35	CARDINAL
admet-258	316	5	53 50	CARDINAL
admet-258	316	6	9	CARDINAL
admet-258	317	1	pbpk	PERSON
admet-258	317	2	g	GPE
admet-258	318	1	fassif	ORG
admet-258	318	2	fassif	ORG
admet-258	320	1	obs.	ORG
admet-258	322	1	30	CARDINAL
admet-258	322	2	2.057	MONEY
admet-258	322	3	15.2	CARDINAL
admet-258	324	1	0.3680	MONEY
admet-258	324	2	100	CARDINAL
admet-258	325	1	30	CARDINAL
admet-258	325	2	1.274 14.75	CARDINAL
admet-258	326	1	1.2939	MONEY
admet-258	326	2	30	CARDINAL
admet-258	327	1	0.0250 0.0454	MONEY
admet-258	327	2	0.1250	MONEY
admet-258	327	3	30 14.83	CARDINAL
admet-258	327	4	4.27 18.02	CARDINAL
admet-258	329	1	1.215	MONEY
admet-258	329	2	100	CARDINAL
admet-258	329	3	1.14	CARDINAL
admet-258	330	1	100	CARDINAL
admet-258	330	2	78.0	CARDINAL
admet-258	330	3	78.1	CARDINAL
admet-258	331	1	0.2914	MONEY
admet-258	331	2	30	CARDINAL
admet-258	331	3	1.249 1.225	CARDINAL
admet-258	332	1	0.0052 0.0446 0.0323	MONEY
admet-258	332	2	0.1960	CARDINAL
admet-258	332	3	4(1	CARDINAL
admet-258	332	4	2016	CARDINAL
admet-258	332	5	35	CARDINAL
admet-258	332	6	10.5599	CARDINAL
admet-258	332	7	51	CARDINAL
admet-258	333	1	g -2.5 -2	PERSON
admet-258	336	1	5	CARDINAL
admet-258	337	1	30 to 300	CARDINAL
admet-258	341	1	al. admet	ORG
admet-258	341	2	4(1	CARDINAL
admet-258	341	3	2016	CARDINAL
admet-258	341	4	35	CARDINAL
admet-258	341	5	53 52	CARDINAL
admet-258	343	1	sif	PERSON
admet-258	347	1	daniel gosling	PERSON
admet-258	347	2	philippe monbaron	PERSON
admet-258	349	1	1	CARDINAL
admet-258	349	2	l. aarons	PERSON
admet-258	349	3	m. bergstrand	PERSON
admet-258	349	4	m.b. bolger	PERSON
admet-258	349	5	a. galetin	PERSON
admet-258	349	6	o. hatley	PERSON
admet-258	349	7	m. jamei	PERSON
admet-258	349	8	r. lloyd	PERSON
admet-258	349	9	x. pepin	PERSON
admet-258	349	10	a. rostami-hodjegan	PERSON
admet-258	349	11	e. sjögren	PERSON
admet-258	349	12	c. tannergren	PERSON
admet-258	349	13	d.b. turner	ORG
admet-258	349	14	c. wagner	PERSON
admet-258	349	15	w. weitschies	PERSON
admet-258	349	16	j. dressman	PERSON
admet-258	349	17	european journal of pharmaceutical sciences	ORG
admet-258	349	18	57	DATE
admet-258	349	19	2014	DATE
admet-258	349	20	300	CARDINAL
admet-258	350	1	2	CARDINAL
admet-258	350	2	a.w basit	PERSON
admet-258	350	3	s. murdan	PERSON
admet-258	350	4	60(1	CARDINAL
admet-258	350	5	2008	DATE
admet-258	350	6	6370	CARDINAL
admet-258	351	1	3	CARDINAL
admet-258	351	2	r. holm	PERSON
admet-258	351	3	a. mullertz	PERSON
admet-258	351	4	h. mu	PERSON
admet-258	351	5	453(1	CARDINAL
admet-258	351	6	2013	DATE
admet-258	351	7	44	CARDINAL
admet-258	352	1	4	CARDINAL
admet-258	352	2	g. amidon	PERSON
admet-258	352	3	h. lennernäs	PERSON
admet-258	352	4	v. shah	PERSON
admet-258	352	5	j. crison	PERSON
admet-258	352	6	1995	DATE
admet-258	352	7	413	CARDINAL
admet-258	353	1	5	CARDINAL
admet-258	353	2	h. jones	PERSON
admet-258	353	3	n. parrott	PERSON
admet-258	353	4	g. ohlenbusch	PERSON
admet-258	353	5	t. lavé	PERSON
admet-258	353	6	45(12	CARDINAL
admet-258	353	7	2006	DATE
admet-258	353	8	1213-1226	CARDINAL
admet-258	354	1	6	CARDINAL
admet-258	354	2	y. gao	PERSON
admet-258	354	3	r.a. carr	PERSON
admet-258	354	4	j.k. spence	ORG
admet-258	354	5	w.w.	GPE
admet-258	354	6	wang	ORG
admet-258	354	7	t.m. turner	PERSON
admet-258	354	8	j.m. lipari	PERSON
admet-258	354	9	j.m. miller	PERSON
admet-258	354	10	2010	DATE
admet-258	354	11	1516-1526	CARDINAL
admet-258	355	1	7	CARDINAL
admet-258	355	2	m. hagio	PERSON
admet-258	355	3	m. matsumoto	PERSON
admet-258	355	4	m. fukushima	PERSON
admet-258	355	5	h. hara	PERSON
admet-258	355	6	s. ishizuka	PERSON
admet-258	355	7	50(1	CARDINAL
admet-258	355	8	2009	DATE
admet-258	355	9	173	CARDINAL
admet-258	356	1	8	CARDINAL
admet-258	356	2	j. m. dietschy	PERSON
admet-258	356	3	9(3	CARDINAL
admet-258	356	4	1968	DATE
admet-258	356	5	297	CARDINAL
admet-258	357	1	9	CARDINAL
admet-258	357	2	t. hara	PERSON
admet-258	357	3	w. ryoichi	PERSON
admet-258	357	4	n. shunji	PERSON
admet-258	357	5	journal of pharmacy & pharmaceutical sciences	ORG
admet-258	357	6	2012	DATE
admet-258	357	7	510-518	CARDINAL
admet-258	358	1	10	CARDINAL
admet-258	358	2	h. musther	PERSON
admet-258	358	3	a. olivares-morales	PERSON
admet-258	358	4	o.j.	GPE
admet-258	358	5	hatley	ORG
admet-258	358	6	b. liu	PERSON
admet-258	358	7	a. rostami hodjegan	PERSON
admet-258	358	8	european journal of pharmaceutical sciences	ORG
admet-258	358	9	57	DATE
admet-258	358	10	2014	DATE
admet-258	358	11	280	CARDINAL
admet-258	359	1	11	CARDINAL
admet-258	359	2	m. arndt	PERSON
admet-258	359	3	h. chokshi	PERSON
admet-258	359	4	k. tang	PERSON
admet-258	359	5	n.j	GPE
admet-258	359	6	parrott	PERSON
admet-258	359	7	c. reppas	PERSON
admet-258	360	1	j.b. dressman	PERSON
admet-258	360	2	european journal of pharmaceutics	ORG
admet-258	360	3	biopharmaceutics	ORG
admet-258	360	4	84(3	CARDINAL
admet-258	360	5	2013	DATE
admet-258	360	6	633-641	CARDINAL
admet-258	361	1	12	CARDINAL
admet-258	361	2	n. parrott	PERSON
admet-258	361	3	n. paquereau	PERSON
admet-258	361	4	t. lave	GPE
admet-258	361	5	2005	DATE
admet-258	361	6	2327-2343	DATE
admet-258	362	1	13	CARDINAL
admet-258	362	2	f. wohnsland	PERSON
admet-258	362	3	journal of medicinal chemistry 44(6	ORG
admet-258	362	4	2001	DATE
admet-258	362	5	923	CARDINAL
admet-258	363	1	14	CARDINAL
admet-258	363	2	e. jantratid	PERSON
admet-258	363	3	n. janssen	PERSON
admet-258	363	4	c. reppas	GPE
admet-258	363	5	j.b. dressman	PERSON
admet-258	363	6	2008	DATE
admet-258	363	7	1663	CARDINAL
admet-258	364	1	15	CARDINAL
admet-258	364	2	s. mukaratirwa	PERSON
admet-258	364	3	6(3	CARDINAL
admet-258	364	4	2008	DATE
admet-258	364	5	166	CARDINAL
admet-258	365	1	16	CARDINAL
admet-258	365	2	j.m.	GPE
admet-258	365	3	desesso	NORP
admet-258	365	4	a.l. williams	PERSON
admet-258	365	5	annual	DATE
admet-258	365	6	43	DATE
admet-258	365	7	353	CARDINAL
admet-258	366	1	17	CARDINAL
admet-258	366	2	t.t. kararli	ORG
admet-258	366	3	biopharmaceutics & drug	ORG
admet-258	366	4	16 (1995	DATE
admet-258	366	5	351	CARDINAL
admet-258	367	1	18	CARDINAL
admet-258	367	2	z.r.	GPE
admet-258	367	3	m.l. bailey	PERSON
admet-258	367	4	p.b. hylemon	PERSON
admet-258	367	5	8(4	CARDINAL
admet-258	367	6	1988	DATE
admet-258	367	7	892	CARDINAL
admet-258	367	8	4(1	CARDINAL
admet-258	367	9	2016	CARDINAL
admet-258	367	10	35	CARDINAL
admet-258	367	11	10.5599	CARDINAL
admet-258	367	12	53	CARDINAL
admet-258	367	13	19	CARDINAL
admet-258	367	14	s.c.	GPE
admet-258	367	15	rabbie	GPE
admet-258	368	1	varum	PERSON
admet-258	368	2	f. afonso-pereira	PERSON
admet-258	368	3	a.w. basit	PERSON
admet-258	368	4	european journal of pharmaceutical sciences	ORG
admet-258	368	5	62	DATE
admet-258	368	6	2014	DATE
admet-258	368	7	76-85	DATE
admet-258	369	1	20	CARDINAL
admet-258	369	2	s.d mithani	PERSON
admet-258	369	3	c.n.	GPE
admet-258	369	4	j. b. dressman	PERSON
admet-258	369	5	13(1	CARDINAL
admet-258	369	6	1996) 163167	DATE
admet-258	370	1	21	CARDINAL
admet-258	370	2	m. germani	PERSON
admet-258	370	3	p. crivori	PERSON
admet-258	370	4	m. rocchetti	PERSON
admet-258	370	5	burton	PERSON
admet-258	370	6	a.g. wilson	GPE
admet-258	370	7	m.e. smith	PERSON
admet-258	370	8	i. pogessi	PERSON
admet-258	370	9	european journal of pharmaceutical sciences	ORG
admet-258	370	10	31	DATE
admet-258	370	11	2007	DATE
admet-258	370	12	190	CARDINAL
admet-258	371	1	22	CARDINAL
admet-258	371	2	h. m. jones	PERSON
admet-258	371	3	i. b. gardner	PERSON
admet-258	371	4	k. j. watson	PERSON
admet-258	371	5	2009	DATE
admet-258	371	6	155	CARDINAL
admet-258	372	1	2016	DATE
admet-258	372	2	iapc	ORG
admet-258	372	3	zagreb	GPE
admet-258	372	4	croatia	GPE
admet-258	373	1	http://creativecommons.org/licenses/by/3.0/	ORG
admet-258	373	2	http://creativecommons.org/licenses/by/3.0/	ORG