id	sid	eid	entity	type
admet-2582	1	1	disitamab vedotin doi:	ORG
admet-2582	1	2	1	CARDINAL
admet-2582	1	3	13(2	CARDINAL
admet-2582	1	4	2025	CARDINAL
admet-2582	1	5	2582	CARDINAL
admet-2582	1	6	issn	PERSON
admet-2582	1	7	1848-7718	DATE
admet-2582	1	8	disitamab vedotin ling wang1,2	ORG
admet-2582	1	9	limeng zhu1,2	PERSON
admet-2582	1	10	wang3	PRODUCT
admet-2582	1	11	dong4	PERSON
admet-2582	1	12	zhihao	NORP
admet-2582	1	13	jing jiang2,5	PERSON
admet-2582	1	14	1remegen co.	DATE
admet-2582	1	15	yantai	GPE
admet-2582	1	16	264000	DATE
admet-2582	1	17	shandong	GPE
admet-2582	1	18	china 2rongchang	ORG
admet-2582	1	19	264003	DATE
admet-2582	1	20	shandong	GPE
admet-2582	1	21	china	GPE
admet-2582	1	22	3new	CARDINAL
admet-2582	1	23	york university	ORG
admet-2582	1	24	new york	GPE
admet-2582	1	25	ny	GPE
admet-2582	1	26	pharma tech co. ltd	ORG
admet-2582	1	27	beijing	GPE
admet-2582	1	28	china 5department	ORG
admet-2582	1	29	binzhou medical university	ORG
admet-2582	1	30	264003	DATE
admet-2582	1	31	shandong	GPE
admet-2582	1	32	china	GPE
admet-2582	1	33	jjiang@bzmc.edu.cn	PERSON
admet-2582	1	34	november 10, 2024	DATE
admet-2582	1	35	february 22, 2025	DATE
admet-2582	1	36	march 14, 2025	DATE
admet-2582	1	37	disitamab vedotin	PERSON
admet-2582	1	38	igg1	ORG
admet-2582	1	39	monomethyl auristatin	PERSON
admet-2582	2	1	disitamab	GPE
admet-2582	4	1	disitamab vedotin	PERSON
admet-2582	5	1	two	CARDINAL
admet-2582	5	2	disitamab	PERSON
admet-2582	5	3	3h	CARDINAL
admet-2582	7	1	disitamab vedotin	PERSON
admet-2582	8	1	disitamab vedotin	PERSON
admet-2582	9	1	disitamab vedotin	PERSON
admet-2582	9	2	70 %	PERCENT
admet-2582	9	3	10 %	PERCENT
admet-2582	9	4	10	CARDINAL
admet-2582	10	1	disitamab	GPE
admet-2582	10	2	disitamab vedotin.	PERSON
admet-2582	11	1	2025	CARDINAL
admet-2582	13	1	monomethyl auristatin	PERSON
admet-2582	14	1	1	CARDINAL
admet-2582	15	1	m. das	PERSON
admet-2582	16	1	al. admet	ORG
admet-2582	16	2	13(2	CARDINAL
admet-2582	16	3	2025	CARDINAL
admet-2582	16	4	2582 2 $16.4 billion	MONEY
admet-2582	16	5	2026	CARDINAL
admet-2582	16	6	2	CARDINAL
admet-2582	17	1	recent years	DATE
admet-2582	18	1	february 2024	DATE
admet-2582	18	2	fifteen	CARDINAL
admet-2582	18	3	about 260	CARDINAL
admet-2582	19	1	disitamab vedotin	PERSON
admet-2582	19	2	remegen. co., ltd,	ORG
admet-2582	19	3	the national medical products administration	ORG
admet-2582	19	4	2021	CARDINAL
admet-2582	20	1	dv	ORG
admet-2582	20	2	fda	ORG
admet-2582	20	3	2020	DATE
admet-2582	20	4	fda	ORG
admet-2582	20	5	the same year	DATE
admet-2582	20	6	3	CARDINAL
admet-2582	21	1	adc	PERSON
admet-2582	21	2	igg1 mab	PERSON
admet-2582	21	3	hertuzumab	PERSON
admet-2582	22	1	7	CARDINAL
admet-2582	23	1	adc	PERSON
admet-2582	23	2	9	CARDINAL
admet-2582	24	1	adme mechanistics	ORG
admet-2582	25	1	10	CARDINAL
admet-2582	27	1	14	CARDINAL
admet-2582	28	1	125i/3h	CARDINAL
admet-2582	29	1	future adc	ORG
admet-2582	30	1	disitamab	PERSON
admet-2582	30	2	remegen co., ltd.	ORG
admet-2582	30	3	3	CARDINAL
admet-2582	31	1	dar	GPE
admet-2582	31	2	3.5	CARDINAL
admet-2582	32	1	radiochemistry	PERSON
admet-2582	32	2	st. louis	GPE
admet-2582	32	3	mo, usa	GPE
admet-2582	32	4	remegen	GPE
admet-2582	32	5	yantai	GPE
admet-2582	33	1	150 cm	QUANTITY
admet-2582	33	2	pharmacia	ORG
admet-2582	33	3	new york	GPE
admet-2582	35	1	3h	CARDINAL
admet-2582	35	2	mc-val-cit-pab-c-[3h	PERSON
admet-2582	35	3	curachem inc.	ORG
admet-2582	35	4	south korea	GPE
admet-2582	35	5	17.57	CARDINAL
admet-2582	35	6	ci	PERSON
admet-2582	36	1	mc-val-cit-pab-c-[3h	PERSON
admet-2582	36	2	17.57	CARDINAL
admet-2582	36	3	ci	PERSON
admet-2582	36	4	curachem inc.	ORG
admet-2582	36	5	south korea	GPE
admet-2582	36	6	rc48-adc	GPE
admet-2582	38	1	3h	CARDINAL
admet-2582	38	2	254	CARDINAL
admet-2582	38	3	3.96	CARDINAL
admet-2582	39	1	3h	CARDINAL
admet-2582	39	2	mc-val-cit-pab-c-[3h	PERSON
admet-2582	39	3	1a	CARDINAL
admet-2582	39	4	1b	CARDINAL
admet-2582	40	1	13(2	CARDINAL
admet-2582	40	2	2025	CARDINAL
admet-2582	40	3	2582	CARDINAL
admet-2582	40	4	disitamab vedotin pharmacokinetics	PERSON
admet-2582	40	5	3	CARDINAL
admet-2582	40	6	1	CARDINAL
admet-2582	40	7	3h	CARDINAL
admet-2582	40	8	mc-val-cit-pab-c-[3h	PERSON
admet-2582	40	9	animal technology co., ltd (	ORG
admet-2582	40	10	2018-0001	DATE
admet-2582	40	11	2016-0011	CARDINAL
admet-2582	40	12	2012-002	DATE
admet-2582	40	13	2012-0004	DATE
admet-2582	41	1	charles river laboratories	ORG
admet-2582	41	2	beijing	GPE
admet-2582	43	1	300	CARDINAL
admet-2582	46	1	rc48-adc	GPE
admet-2582	46	2	twenty-four	MONEY
admet-2582	46	3	8 to 12 weeks old	DATE
admet-2582	46	4	approximately 200	CARDINAL
admet-2582	46	5	rc48	PRODUCT
admet-2582	46	6	4, 8	DATE
admet-2582	46	7	16 mg/kg	QUANTITY
admet-2582	46	8	rc48	PRODUCT
admet-2582	46	9	8 mg/kg rc48 ab	QUANTITY
admet-2582	46	10	0.16 mg/kg	QUANTITY
admet-2582	47	1	0min	GPE
admet-2582	47	2	predose	GPE
admet-2582	47	3	1	CARDINAL
admet-2582	47	4	10	DATE
admet-2582	47	5	2	DATE
admet-2582	47	6	1	CARDINAL
admet-2582	47	7	2	DATE
admet-2582	47	8	3	DATE
admet-2582	47	9	6	DATE
admet-2582	47	10	8	DATE
admet-2582	47	11	10	DATE
admet-2582	47	12	12	DATE
admet-2582	47	13	14	DATE
admet-2582	47	14	17	DATE
admet-2582	47	15	21	DATE
admet-2582	47	16	24	DATE
admet-2582	47	17	28 days	DATE
admet-2582	47	18	4 °	QUANTITY
admet-2582	47	19	1000 to 2000	CARDINAL
admet-2582	47	20	10 min	TIME
admet-2582	48	1	three	CARDINAL
admet-2582	49	1	three	CARDINAL
admet-2582	50	1	125i-rc48-adc	PRODUCT
admet-2582	50	2	4	CARDINAL
admet-2582	50	3	24	DATE
admet-2582	50	4	72	DATE
admet-2582	50	5	168	CARDINAL
admet-2582	50	6	i.v.	PERSON
admet-2582	51	1	12 mg/kg	QUANTITY
admet-2582	52	1	23	CARDINAL
admet-2582	54	1	20 %	PERCENT
admet-2582	54	2	10 %	PERCENT
admet-2582	56	1	μg·eqv·g-1	ORG
admet-2582	58	1	packard instrument co.	ORG
admet-2582	60	1	3h	CARDINAL
admet-2582	60	2	nci	GPE
admet-2582	60	3	twenty-five	CARDINAL
admet-2582	60	4	4	CARDINAL
admet-2582	60	5	24	DATE
admet-2582	60	6	72	DATE
admet-2582	60	7	168	CARDINAL
admet-2582	60	8	336	CARDINAL
admet-2582	60	9	i.v.	PERSON
admet-2582	61	1	12 mg/kg	QUANTITY
admet-2582	62	1	3h	CARDINAL
admet-2582	62	2	-rc48-adc	ORG
admet-2582	63	1	6	CARDINAL
admet-2582	63	2	10,000	CARDINAL
admet-2582	63	3	10 min	TIME
admet-2582	63	4	m. das et al. admet	PERSON
admet-2582	63	5	13(2	CARDINAL
admet-2582	63	6	2025	CARDINAL
admet-2582	63	7	2582 4	DATE
admet-2582	64	1	1 m	QUANTITY
admet-2582	64	2	koh	PERSON
admet-2582	64	3	90 °	QUANTITY
admet-2582	65	1	μg·eqv·g-1	ORG
admet-2582	66	1	3h	CARDINAL
admet-2582	67	1	125i-rc48-adc	QUANTITY
admet-2582	67	2	3h	CARDINAL
admet-2582	67	3	0 to 24 h	PERCENT
admet-2582	67	4	24	CARDINAL
admet-2582	67	5	288	CARDINAL
admet-2582	67	6	336	CARDINAL
admet-2582	67	7	12 mg	QUANTITY
admet-2582	67	8	125i-rc48-adc	PRODUCT
admet-2582	67	9	twelve	CARDINAL
admet-2582	68	1	0 to 8 h	PERCENT
admet-2582	68	2	8 to 24	DATE
admet-2582	68	3	336	CARDINAL
admet-2582	68	4	8 mg/kg	QUANTITY
admet-2582	69	1	3h	CARDINAL
admet-2582	69	2	six	CARDINAL
admet-2582	74	1	8 mg/kg	QUANTITY
admet-2582	74	2	3h	CARDINAL
admet-2582	75	1	1	CARDINAL
admet-2582	75	2	2	DATE
admet-2582	75	3	3	DATE
admet-2582	75	4	5	DATE
admet-2582	75	5	8	DATE
admet-2582	75	6	12	DATE
admet-2582	75	7	24	CARDINAL
admet-2582	75	8	4	CARDINAL
admet-2582	75	9	8	DATE
admet-2582	75	10	24	DATE
admet-2582	75	11	48	DATE
admet-2582	75	12	72	DATE
admet-2582	77	1	24-hour	TIME
admet-2582	78	1	8 mg/200 ci/kg	QUANTITY
admet-2582	79	1	3h	CARDINAL
admet-2582	79	2	rc48-adc	GPE
admet-2582	79	3	12 mg/200	QUANTITY
admet-2582	79	4	3h	CARDINAL
admet-2582	80	1	3h]-mmae	CARDINAL
admet-2582	80	2	3	CARDINAL
admet-2582	80	3	america	GPE
admet-2582	83	1	150×4.6 mm	QUANTITY
admet-2582	83	2	3.0 μm	CARDINAL
admet-2582	83	3	uk	GPE
admet-2582	83	4	0.4 %	PERCENT
admet-2582	83	5	3.2	CARDINAL
admet-2582	83	6	0.7 ml	QUANTITY
admet-2582	84	1	0 %	PERCENT
admet-2582	84	2	3 min	DATE
admet-2582	84	3	35 %	PERCENT
admet-2582	84	4	30 min	TIME
admet-2582	84	5	35 %	PERCENT
admet-2582	84	6	45 min	DATE
admet-2582	84	7	100 %	PERCENT
admet-2582	84	8	55 min	DATE
admet-2582	84	9	100 %	PERCENT
admet-2582	84	10	58 min	DATE
admet-2582	84	11	0 %	PERCENT
admet-2582	84	12	60 min	TIME
admet-2582	84	13	72 min	DATE
admet-2582	85	1	4:1	CARDINAL
admet-2582	86	1	rc48-adc	GPE
admet-2582	86	2	2	CARDINAL
admet-2582	87	1	1	CARDINAL
admet-2582	88	1	rc48-adc	GPE
admet-2582	88	2	4	CARDINAL
admet-2582	88	3	13(2	CARDINAL
admet-2582	88	4	2025	CARDINAL
admet-2582	88	5	2582	CARDINAL
admet-2582	88	6	disitamab vedotin pharmacokinetics	PERSON
admet-2582	88	7	5 16 mg/kg	QUANTITY
admet-2582	88	8	2	CARDINAL
admet-2582	88	9	1	CARDINAL
admet-2582	88	10	half	CARDINAL
admet-2582	88	11	half	CARDINAL
admet-2582	89	1	p>0.05	ORG
admet-2582	90	1	1	CARDINAL
admet-2582	91	1	approximately the same	DATE
admet-2582	91	2	half	CARDINAL
admet-2582	91	3	1	CARDINAL
admet-2582	92	1	4	CARDINAL
admet-2582	92	2	1	CARDINAL
admet-2582	93	1	2	CARDINAL
admet-2582	93	2	rc48-adc	GPE
admet-2582	93	3	rc48-adc(4	GPE
admet-2582	93	4	16 mg/kg	QUANTITY
admet-2582	93	5	rc48-adc	GPE
admet-2582	93	6	8+0.16 mg/kg	QUANTITY
admet-2582	93	7	±	CARDINAL
admet-2582	93	8	6	CARDINAL
admet-2582	94	1	linear	ORG
admet-2582	94	2	4-8 mg/kg	QUANTITY
admet-2582	94	3	16 mg/kg	QUANTITY
admet-2582	94	4	2	CARDINAL
admet-2582	94	5	1	CARDINAL
admet-2582	95	1	rc48-adc	GPE
admet-2582	95	2	8 mg/kg	QUANTITY
admet-2582	95	3	rc48-adc	GPE
admet-2582	95	4	2	CARDINAL
admet-2582	95	5	1	CARDINAL
admet-2582	96	1	8 mg/kg	QUANTITY
admet-2582	96	2	approximately 0.09	CARDINAL
admet-2582	96	3	5.56 %	PERCENT
admet-2582	96	4	1	CARDINAL
admet-2582	97	1	rc48-adc	GPE
admet-2582	97	2	2	CARDINAL
admet-2582	98	1	rc48-adc	GPE
admet-2582	99	1	rc48-adc	GPE
admet-2582	100	1	rc48-adc	GPE
admet-2582	100	2	rc48-adc	GPE
admet-2582	101	1	rc48-adc	GPE
admet-2582	101	2	13	CARDINAL
admet-2582	102	1	m. das et al. admet	PERSON
admet-2582	102	2	13(2	CARDINAL
admet-2582	102	3	2025	CARDINAL
admet-2582	102	4	2582 6	DATE
admet-2582	102	5	1	CARDINAL
admet-2582	102	6	rc48-adc	GPE
admet-2582	102	7	rc48-adc	GPE
admet-2582	102	8	4	CARDINAL
admet-2582	102	9	to16 mg/kg	PRODUCT
admet-2582	102	10	rc48-adc	GPE
admet-2582	102	11	8 + 0.16 mg/kg	QUANTITY
admet-2582	103	1	kg-1	DATE
admet-2582	103	2	rc48-adc 4	GPE
admet-2582	106	1	206.94± 83.34 0.02±0.00	MONEY
admet-2582	108	1	463.83 2229.21±	MONEY
admet-2582	108	2	613.9	CARDINAL
admet-2582	108	3	5.62	CARDINAL
admet-2582	108	4	165.47	CARDINAL
admet-2582	108	5	0.47	CARDINAL
admet-2582	108	6	79.75	CARDINAL
admet-2582	108	7	rc48-adc	EVENT
admet-2582	108	8	82.44 0.02±0.00	MONEY
admet-2582	109	1	347.88	CARDINAL
admet-2582	109	2	0.41	CARDINAL
admet-2582	109	3	45.07	CARDINAL
admet-2582	109	4	12.34±11.66	CARDINAL
admet-2582	109	5	4.15±1.05	CARDINAL
admet-2582	110	1	184.21± 48.56 0.04±0.06	QUANTITY
admet-2582	110	2	6.70± 1.86	CARDINAL
admet-2582	110	3	119.47	CARDINAL
admet-2582	110	4	0.14	CARDINAL
admet-2582	110	5	44.18	CARDINAL
admet-2582	110	6	rc48-adc	GPE
admet-2582	110	7	52.23	CARDINAL
admet-2582	110	8	0.04±0.06	PERSON
admet-2582	110	9	195.97	CARDINAL
admet-2582	110	10	208.01	CARDINAL
admet-2582	110	11	26.48	CARDINAL
admet-2582	110	12	17.34±14.66	DATE
admet-2582	110	13	rc48-adc 16	FAC
admet-2582	111	1	156.86± 114.43 0.10±0.20	MONEY
admet-2582	111	2	2840.88	CARDINAL
admet-2582	111	3	6.62	CARDINAL
admet-2582	111	4	248.72	CARDINAL
admet-2582	111	5	1.00	CARDINAL
admet-2582	111	6	107.77	CARDINAL
admet-2582	111	7	rc48-adc	GPE
admet-2582	112	1	974.01	CARDINAL
admet-2582	112	2	2.27 566.5±	CARDINAL
admet-2582	112	3	54.59	CARDINAL
admet-2582	112	4	26.90±5.22	CARDINAL
admet-2582	112	5	rc48-adc	EVENT
admet-2582	113	1	rc48-adc	GPE
admet-2582	113	2	185.93±	CARDINAL
admet-2582	113	3	56.33	CARDINAL
admet-2582	113	4	100.55±12.81	CARDINAL
admet-2582	113	5	176.88 1.59± 0.29 276.85±	MONEY
admet-2582	113	6	54.99	CARDINAL
admet-2582	113	7	0.16	CARDINAL
admet-2582	113	8	227.67±103.11	CARDINAL
admet-2582	113	9	56.74	CARDINAL
admet-2582	116	1	3a	CARDINAL
admet-2582	117	1	3c	CARDINAL
admet-2582	118	1	approximately 90 %	PERCENT
admet-2582	120	1	3c	CARDINAL
admet-2582	123	1	rc48-adc	GPE
admet-2582	124	1	rc48-adc	GPE
admet-2582	125	1	125i-rc48-adc	PRODUCT
admet-2582	125	2	rc48-adc	GPE
admet-2582	126	1	125i	CARDINAL
admet-2582	127	1	125i-rc48-adc	PRODUCT
admet-2582	127	2	125i-rc48-adc	PRODUCT
admet-2582	128	1	13(2	CARDINAL
admet-2582	128	2	2025	CARDINAL
admet-2582	128	3	2582	CARDINAL
admet-2582	128	4	disitamab vedotin pharmacokinetics	PERSON
admet-2582	128	5	7	CARDINAL
admet-2582	129	1	rc48-adc	GPE
admet-2582	129	2	125i-rc48-adc	PRODUCT
admet-2582	130	1	g	GPE
admet-2582	130	2	g	ORG
admet-2582	130	3	3	CARDINAL
admet-2582	130	4	125i]–rc48-adc	DATE
admet-2582	130	5	12 mg/kg	QUANTITY
admet-2582	130	6	±	CARDINAL
admet-2582	130	7	5	CARDINAL
admet-2582	132	1	liv	PRODUCT
admet-2582	134	1	l 4	DATE
admet-2582	134	2	168	CARDINAL
admet-2582	135	1	liv	PRODUCT
admet-2582	135	2	ac	ORG
admet-2582	136	1	l 4	DATE
admet-2582	136	2	168	CARDINAL
admet-2582	136	3	0	CARDINAL
admet-2582	137	1	0	CARDINAL
admet-2582	137	2	io ak ti vi ty	FAC
admet-2582	137	3	io ak ti vi ty	FAC
admet-2582	137	4	l 4 h 24 72	DATE
admet-2582	137	5	168	CARDINAL
admet-2582	137	6	4	CARDINAL
admet-2582	137	7	24 72	DATE
admet-2582	137	8	168	CARDINAL
admet-2582	137	9	m. das et al. admet	PERSON
admet-2582	137	10	13(2	CARDINAL
admet-2582	137	11	2025	CARDINAL
admet-2582	137	12	2582 8	DATE
admet-2582	138	1	4a	CARDINAL
admet-2582	138	2	24 hours	TIME
admet-2582	138	3	72 hours	TIME
admet-2582	139	1	4 hours and 24 hours	TIME
admet-2582	139	2	about 52.67 %	PERCENT
admet-2582	140	1	336	CARDINAL
admet-2582	140	2	about 1.93	CARDINAL
admet-2582	141	1	g	GPE
admet-2582	141	2	g	GPE
admet-2582	141	3	g	GPE
admet-2582	141	4	g	GPE
admet-2582	142	1	4	CARDINAL
admet-2582	142	2	3h	CARDINAL
admet-2582	142	3	12 mg/kg	QUANTITY
admet-2582	142	4	±	CARDINAL
admet-2582	142	5	6	CARDINAL
admet-2582	143	1	ar ro w tu m	PERSON
admet-2582	144	1	ute ru s	FAC
admet-2582	144	2	te st	GPE
admet-2582	144	3	al w al l hea rt	FAC
admet-2582	144	4	sa liv ar y g la	FAC
admet-2582	144	5	st om ac	PERSON
admet-2582	150	1	fa	ORG
admet-2582	150	2	al m usc le	ORG
admet-2582	151	1	120	CARDINAL
admet-2582	154	1	o	DATE
admet-2582	154	2	l 4	DATE
admet-2582	154	3	168	CARDINAL
admet-2582	154	4	336 hr tu	QUANTITY
admet-2582	154	5	2 4 6 8	TIME
admet-2582	161	1	o	DATE
admet-2582	161	2	l 4	DATE
admet-2582	161	3	168	CARDINAL
admet-2582	161	4	336	CARDINAL
admet-2582	161	5	0 1000 2000 3000 4000 5000	MONEY
admet-2582	161	6	0	CARDINAL
admet-2582	161	7	0 500 1000 1500 2000	MONEY
admet-2582	161	8	0	CARDINAL
admet-2582	161	9	io ak ti vi ty	FAC
admet-2582	162	1	io ak ti vi ty	FAC
admet-2582	163	1	l 4 h 24 72	DATE
admet-2582	163	2	168	CARDINAL
admet-2582	163	3	336	CARDINAL
admet-2582	163	4	4	CARDINAL
admet-2582	163	5	24 72	DATE
admet-2582	163	6	168	CARDINAL
admet-2582	163	7	336	CARDINAL
admet-2582	163	8	13(2	CARDINAL
admet-2582	163	9	2025	CARDINAL
admet-2582	163	10	2582	CARDINAL
admet-2582	163	11	disitamab vedotin pharmacokinetics	PERSON
admet-2582	163	12	9	CARDINAL
admet-2582	163	13	4c	CARDINAL
admet-2582	164	1	4c	CARDINAL
admet-2582	165	1	18.57	CARDINAL
admet-2582	165	2	2.04	CARDINAL
admet-2582	165	3	1.81	CARDINAL
admet-2582	165	4	1.11	CARDINAL
admet-2582	165	5	4c	CARDINAL
admet-2582	167	1	3h	CARDINAL
admet-2582	167	2	3h	CARDINAL
admet-2582	168	1	rc48-adc	GPE
admet-2582	168	2	rc48-adc	GPE
admet-2582	168	3	3h	CARDINAL
admet-2582	168	4	rc48-adc	GPE
admet-2582	169	1	rc48-adc	GPE
admet-2582	170	1	5a	CARDINAL
admet-2582	171	1	5	CARDINAL
admet-2582	172	1	125i]–rc48-adc	DATE
admet-2582	172	2	3h	CARDINAL
admet-2582	172	3	-rc48-adc	ORG
admet-2582	173	1	125i]–rc48-adc	DATE
admet-2582	173	2	12 mg/kg	QUANTITY
admet-2582	173	3	±	CARDINAL
admet-2582	173	4	12	CARDINAL
admet-2582	173	5	125i]–rc48-adc	DATE
admet-2582	173	6	8 mg/kg	QUANTITY
admet-2582	173	7	±	CARDINAL
admet-2582	173	8	6	CARDINAL
admet-2582	173	9	3h	CARDINAL
admet-2582	173	10	-rc48-adc	ORG
admet-2582	173	11	8 mg/kg	QUANTITY
admet-2582	173	12	±	CARDINAL
admet-2582	173	13	6	CARDINAL
admet-2582	173	14	3h	CARDINAL
admet-2582	173	15	-rc48-adc	ORG
admet-2582	173	16	8 mg/kg	QUANTITY
admet-2582	173	17	±	CARDINAL
admet-2582	173	18	6	CARDINAL
admet-2582	177	1	m. das	PERSON
admet-2582	178	1	al. admet	ORG
admet-2582	178	2	13(2	CARDINAL
admet-2582	178	3	2025	CARDINAL
admet-2582	178	4	2582 10	DATE
admet-2582	178	5	336	CARDINAL
admet-2582	178	6	75.64±2.80	CARDINAL
admet-2582	178	7	0.90±0.13 %	PERCENT
admet-2582	180	1	24-hour	TIME
admet-2582	180	2	0.17±0.06 %	PERCENT
admet-2582	180	3	5b	CARDINAL
admet-2582	181	1	rc48-adc	GPE
admet-2582	182	1	rc48-adc	GPE
admet-2582	183	1	3h	CARDINAL
admet-2582	183	2	5c	CARDINAL
admet-2582	184	1	9.17	CARDINAL
admet-2582	184	2	74.69 %	PERCENT
admet-2582	185	1	the first week	DATE
admet-2582	185	2	77.11 %	PERCENT
admet-2582	186	1	78.44 %	PERCENT
admet-2582	186	2	0-72 h excretion	ORG
admet-2582	186	3	5c	CARDINAL
admet-2582	187	1	rc48-adc	GPE
admet-2582	188	1	2	CARDINAL
admet-2582	188	2	11	CARDINAL
admet-2582	188	3	mmae(m717	PERSON
admet-2582	188	4	m719-1	ORG
admet-2582	188	5	m719-2	ORG
admet-2582	188	6	m719-3	ORG
admet-2582	188	7	m719-4	ORG
admet-2582	188	8	m719-5	ORG
admet-2582	188	9	m733-1	DATE
admet-2582	188	10	m703-1	DATE
admet-2582	189	1	mmae	PERSON
admet-2582	189	2	10	CARDINAL
admet-2582	189	3	m719-5	ORG
admet-2582	189	4	m703-1	CARDINAL
admet-2582	190	1	3h	CARDINAL
admet-2582	190	2	6	CARDINAL
admet-2582	190	3	2	CARDINAL
admet-2582	190	4	11	CARDINAL
admet-2582	192	1	1 m717	CARDINAL
admet-2582	193	1	+ 718.5113 718.5100	DATE
admet-2582	193	2	2	CARDINAL
admet-2582	193	3	+ 720.4906 720.4895	PERCENT
admet-2582	193	4	3	CARDINAL
admet-2582	193	5	+ 720.4906	DATE
admet-2582	193	6	4	CARDINAL
admet-2582	193	7	+ 720.4906 720.4891	CARDINAL
admet-2582	193	8	-1.50	PRODUCT
admet-2582	193	9	5	CARDINAL
admet-2582	193	10	720.4896	CARDINAL
admet-2582	193	11	-1.00	PRODUCT
admet-2582	193	12	6	CARDINAL
admet-2582	193	13	+ 720.4906 720.4895	PERCENT
admet-2582	193	14	7	CARDINAL
admet-2582	193	15	734.5048	CARDINAL
admet-2582	193	16	9	CARDINAL
admet-2582	193	17	10	CARDINAL
admet-2582	193	18	1	CARDINAL
admet-2582	193	19	704.4943	CARDINAL
admet-2582	193	20	11	CARDINAL
admet-2582	193	21	eight	CARDINAL
admet-2582	193	22	14	CARDINAL
admet-2582	194	1	twelve	CARDINAL
admet-2582	195	1	11	CARDINAL
admet-2582	196	1	10	CARDINAL
admet-2582	196	2	m719-5	ORG
admet-2582	197	1	rc48-adc	GPE
admet-2582	198	1	13(2	CARDINAL
admet-2582	198	2	2025	CARDINAL
admet-2582	198	3	2582	CARDINAL
admet-2582	198	4	disitamab vedotin pharmacokinetics	PERSON
admet-2582	198	5	11	CARDINAL
admet-2582	199	1	yip	PERSON
admet-2582	200	1	14	CARDINAL
admet-2582	200	2	3h]-mmae	ORDINAL
admet-2582	201	1	han et al	PERSON
admet-2582	202	1	15	CARDINAL
admet-2582	202	2	asrc48-adc	ORG
admet-2582	203	1	64.46 %	PERCENT
admet-2582	203	2	54.33 %	PERCENT
admet-2582	204	1	6	CARDINAL
admet-2582	205	1	disitamab vedotin	PERSON
admet-2582	206	1	disitamab edotin	PERSON
admet-2582	206	2	disitamab vedotin	PERSON
admet-2582	207	1	al. admet	ORG
admet-2582	207	2	13(2	CARDINAL
admet-2582	207	3	2025	CARDINAL
admet-2582	207	4	2582 12	DATE
admet-2582	208	1	disitamab	GPE
admet-2582	209	1	rc48-adc	GPE
admet-2582	210	1	pk/pd	ORG
admet-2582	213	1	1	CARDINAL
admet-2582	213	2	s. parakh	PERSON
admet-2582	213	3	scott	PERSON
admet-2582	215	1	25	CARDINAL
admet-2582	216	1	https://doi.org/10.3390/molecules25204764	NORP
admet-2582	217	1	2	CARDINAL
admet-2582	217	2	k. nawaz	PERSON
admet-2582	217	3	r.m. webster	PERSON
admet-2582	219	1	nat	PERSON
admet-2582	220	1	20	CARDINAL
admet-2582	220	2	2021	CARDINAL
admet-2582	220	3	583	CARDINAL
admet-2582	222	1	3	CARDINAL
admet-2582	222	2	j. jiang	PERSON
admet-2582	222	3	l. dong	PERSON
admet-2582	222	4	l. wang	PERSON
admet-2582	222	5	l. wang	PERSON
admet-2582	222	6	j. zhang	PERSON
admet-2582	222	7	f. chen	PERSON
admet-2582	222	8	x. zhang	PERSON
admet-2582	222	9	m. huang	PERSON
admet-2582	222	10	s. li	PERSON
admet-2582	222	11	w. ma	PERSON
admet-2582	222	12	q. xu	PERSON
admet-2582	222	13	c. huang	PERSON
admet-2582	222	14	j. fang	PERSON
admet-2582	222	15	c. wang	PERSON
admet-2582	224	1	european journal of pharmaceutical sciences	ORG
admet-2582	224	2	93	CARDINAL
admet-2582	224	3	2016	CARDINAL
admet-2582	224	4	274	CARDINAL
admet-2582	225	1	4	CARDINAL
admet-2582	225	2	x. sheng	PERSON
admet-2582	225	3	x. yan	PERSON
admet-2582	225	4	l. wang	PERSON
admet-2582	225	5	y. shi	PERSON
admet-2582	225	6	x. yao	PERSON
admet-2582	225	7	h. luo	PERSON
admet-2582	225	8	b. shi	PERSON
admet-2582	225	9	j. liu	PERSON
admet-2582	225	10	z.	PERSON
admet-2582	226	1	g. yu	PERSON
admet-2582	226	2	j. ying	PERSON
admet-2582	226	3	w. han	PERSON
admet-2582	226	4	c. hu	PERSON
admet-2582	226	5	y. ling	PERSON
admet-2582	226	6	z. chi	PERSON
admet-2582	226	7	c. cui	GPE
admet-2582	226	8	l. si	PERSON
admet-2582	226	9	j. fang	PERSON
admet-2582	226	10	a. zhou	PERSON
admet-2582	226	11	j. guo	PERSON
admet-2582	227	1	rc48-adc	GPE
admet-2582	228	1	27	CARDINAL
admet-2582	228	2	2021	CARDINAL
admet-2582	228	3	43	CARDINAL
admet-2582	230	1	5	CARDINAL
admet-2582	230	2	z. peng	PERSON
admet-2582	230	3	t. liu	PERSON
admet-2582	230	4	j. wei	PERSON
admet-2582	230	5	a. wang	PERSON
admet-2582	230	6	l. yang	PERSON
admet-2582	230	7	x. zhang	PERSON
admet-2582	230	8	s. luo	PERSON
admet-2582	230	9	z. li	PERSON
admet-2582	230	10	k. gu	PERSON
admet-2582	230	11	j. lu	PERSON
admet-2582	230	12	j. xu	PERSON
admet-2582	230	13	q.	PERSON
admet-2582	230	14	r. xu	PERSON
admet-2582	230	15	l. zhang	PERSON
admet-2582	230	16	e. li	PERSON
admet-2582	230	17	y. sun	PERSON
admet-2582	230	18	g. yu	PERSON
admet-2582	230	19	c. bai	PERSON
admet-2582	230	20	y. liu	PERSON
admet-2582	230	21	j. zeng	PERSON
admet-2582	230	22	j. ying	PERSON
admet-2582	230	23	x. liang	PERSON
admet-2582	230	24	n. xu	PERSON
admet-2582	230	25	c. gao	PERSON
admet-2582	230	26	y. shu	PERSON
admet-2582	230	27	d. ma	PERSON
admet-2582	230	28	g. dai	PERSON
admet-2582	230	29	s. li	PERSON
admet-2582	230	30	t. deng	PERSON
admet-2582	230	31	y. cui	PERSON
admet-2582	230	32	j. fang	PERSON
admet-2582	230	33	l. shen	PERSON
admet-2582	231	1	rc48	PRODUCT
admet-2582	232	1	41	CARDINAL
admet-2582	232	2	2021	CARDINAL
admet-2582	232	3	1173-1182	DATE
admet-2582	233	1	6	CARDINAL
admet-2582	233	2	y. xu	PERSON
admet-2582	233	3	y. wang	PERSON
admet-2582	233	4	j. gong	PERSON
admet-2582	233	5	x. zhang	PERSON
admet-2582	233	6	z. peng	PERSON
admet-2582	233	7	x. sheng	PERSON
admet-2582	233	8	c. mao	PERSON
admet-2582	233	9	q.	PERSON
admet-2582	233	10	y. bai	PERSON
admet-2582	233	11	y. ba	PERSON
admet-2582	233	12	d. jiang	PERSON
admet-2582	233	13	f. yang	PERSON
admet-2582	233	14	c. qi	PERSON
admet-2582	233	15	j. li	PERSON
admet-2582	233	16	x. wang	PERSON
admet-2582	233	17	j. zhou	PERSON
admet-2582	233	18	m. lu	PERSON
admet-2582	233	19	j. yuan	PERSON
admet-2582	233	20	d. liu	PERSON
admet-2582	233	21	z. wang	PERSON
admet-2582	233	22	j. fang	PERSON
admet-2582	233	23	l. shen	PERSON
admet-2582	234	1	anti-her2	NORP
admet-2582	234	2	rc48-adc	GPE
admet-2582	235	1	24	CARDINAL
admet-2582	235	2	2021	CARDINAL
admet-2582	235	3	913	CARDINAL
admet-2582	236	1	j. kalmuk	PERSON
admet-2582	236	2	d. rinder	PERSON
admet-2582	236	3	c. heltzel	GPE
admet-2582	236	4	a.c. lockhart	PERSON
admet-2582	238	1	17	CARDINAL
admet-2582	238	2	2022	CARDINAL
admet-2582	238	3	427	CARDINAL
admet-2582	239	1	8	CARDINAL
admet-2582	239	2	c. li	PERSON
admet-2582	239	3	c. zhang	PERSON
admet-2582	239	4	r. deng	PERSON
admet-2582	239	5	d. leipold	GPE
admet-2582	239	6	d. li	PERSON
admet-2582	239	7	b. latifi	PERSON
admet-2582	239	8	y. gao	PERSON
admet-2582	239	9	c. zhang	PERSON
admet-2582	239	10	z. li	PERSON
admet-2582	239	11	d. miles	PERSON
admet-2582	239	12	s.c.	GPE
admet-2582	239	13	chen	PERSON
admet-2582	239	14	d. samineni	PERSON
admet-2582	239	15	b. wang	PERSON
admet-2582	239	16	d. lu	PERSON
admet-2582	239	17	s. prabhu	PERSON
admet-2582	239	18	s. girish	PERSON
admet-2582	239	19	a.v. kamath	PERSON
admet-2582	240	1	2019	CARDINAL
admet-2582	240	2	534	CARDINAL
admet-2582	241	1	9	CARDINAL
admet-2582	241	2	liu	PERSON
admet-2582	241	3	c. li	PERSON
admet-2582	243	1	87	CARDINAL
admet-2582	243	2	2021	CARDINAL
admet-2582	243	3	743	CARDINAL
admet-2582	244	1	https://doi.org/10.3390/molecules25204764	NORP
admet-2582	245	1	13(2	CARDINAL
admet-2582	245	2	2025	CARDINAL
admet-2582	245	3	2582	CARDINAL
admet-2582	245	4	disitamab vedotin pharmacokinetics	PERSON
admet-2582	245	5	13	CARDINAL
admet-2582	245	6	10	CARDINAL
admet-2582	245	7	drake	PERSON
admet-2582	245	8	d. rabuka	PERSON
admet-2582	246	1	adc	ORG
admet-2582	247	1	31	CARDINAL
admet-2582	247	2	2017	CARDINAL
admet-2582	247	3	521	CARDINAL
admet-2582	249	1	11	CARDINAL
admet-2582	249	2	kamath	PERSON
admet-2582	249	3	s. iyer	PERSON
admet-2582	253	1	37	DATE
admet-2582	253	2	2016	CARDINAL
admet-2582	253	3	66	CARDINAL
admet-2582	254	1	https://doi.org/10.1002/bdd.1957	ORG
admet-2582	254	2	12	CARDINAL
admet-2582	254	3	j. bolleddula	PERSON
admet-2582	254	4	k. brady	PERSON
admet-2582	254	5	g. bruin	PERSON
admet-2582	254	6	a. lee	PERSON
admet-2582	254	7	j.a. martin	PERSON
admet-2582	254	8	m. walles	PERSON
admet-2582	254	9	k. xu	PERSON
admet-2582	254	10	t.y. yang	PERSON
admet-2582	254	11	x. zhu	GPE
admet-2582	254	12	h. yu	PERSON
admet-2582	256	1	50	CARDINAL
admet-2582	256	2	2022	CARDINAL
admet-2582	256	3	837	CARDINAL
admet-2582	257	1	13	CARDINAL
admet-2582	257	2	u.s.	GPE
admet-2582	257	3	food and drug administration	ORG
admet-2582	259	1	14	CARDINAL
admet-2582	259	2	v. yip	PERSON
admet-2582	259	3	m.v. lee	PERSON
admet-2582	259	4	saad	PERSON
admet-2582	259	5	s. ma	PERSON
admet-2582	259	6	s.c. khojasteh	PERSON
admet-2582	259	7	b.q. shen	PERSON
admet-2582	260	1	sprague	GPE
admet-2582	260	2	dawley rats.	ORG
admet-2582	261	1	10	CARDINAL
admet-2582	261	2	2021	CARDINAL
admet-2582	261	3	1323	DATE
admet-2582	263	1	15	CARDINAL
admet-2582	263	2	han	NORP
admet-2582	263	3	a.k. gopal	GPE
admet-2582	263	4	r. ramchandren	PERSON
admet-2582	263	5	a. goy	PERSON
admet-2582	263	6	r. chen	PERSON
admet-2582	263	7	j.v. matous	PERSON
admet-2582	263	8	m. cooper	PERSON
admet-2582	263	9	l.e. grove	PERSON
admet-2582	263	10	s.c.	GPE
admet-2582	263	11	c.m. lynch	GPE
admet-2582	263	12	o.a. o'connor	ORG
admet-2582	265	1	53	CARDINAL
admet-2582	265	2	2013	DATE
admet-2582	265	3	866	CARDINAL
admet-2582	267	1	2025	CARDINAL
admet-2582	267	2	iapc	ORG
admet-2582	267	3	zagreb	GPE
admet-2582	267	4	croatia	GPE
admet-2582	268	1	http://creativecommons.org/licenses/by/3.0/	ORG
admet-2582	268	2	https://doi.org/10.1002/bdd.1957	NORP
admet-2582	268	3	https://doi.org/10.1124/dmd.121.000461 https://www.accessdata.fda.gov/drugsatfda_docs/nda/2011/125388orig1s000pharmr.pdf https://doi.org/10.3390/jcm10061323 https://doi.org/10.1002/jcph.116	PRODUCT
admet-2582	268	4	http://creativecommons.org/licenses/by/3.0/	ORG