id	sid	eid	entity	type
admet-295	1	1	10.5599	CARDINAL
admet-295	1	2	212	CARDINAL
admet-295	1	3	4(3	CARDINAL
admet-295	1	4	2016	CARDINAL
admet-295	1	5	212	CARDINAL
admet-295	1	6	10.5599	CARDINAL
admet-295	1	7	issn	PERSON
admet-295	1	8	1848-7718	DATE
admet-295	1	9	rashmi r shah	PERSON
admet-295	1	10	8	CARDINAL
admet-295	1	11	buckinghamshire	GPE
admet-295	1	12	uk e	GPE
admet-295	1	13	clinical.safety@hotmail.co.uk	NORP
admet-295	2	1	44	CARDINAL
admet-295	2	2	1753 886348	DATE
admet-295	2	3	may 17,	DATE
admet-295	2	4	2016	DATE
admet-295	2	5	july 12, 2016	DATE
admet-295	2	6	september 30, 2016	DATE
admet-295	6	1	28	CARDINAL
admet-295	6	2	juxta	PERSON
admet-295	10	1	1-3	CARDINAL
admet-295	12	1	31	CARDINAL
admet-295	12	2	2016	DATE
admet-295	12	3	27	CARDINAL
admet-295	12	4	the us food and drug administration	ORG
admet-295	12	5	fda	ORG
admet-295	12	6	first	ORDINAL
admet-295	12	7	may 2001	DATE
admet-295	13	1	two	CARDINAL
admet-295	13	2	fda	ORG
admet-295	13	3	http://www.pub.iapchem.org/ojs/index.php/admet/index mailto:clinical.safety@hotmail.co.uk admet &	ORG
admet-295	13	4	4(3	CARDINAL
admet-295	13	5	2016	CARDINAL
admet-295	13	6	212	CARDINAL
admet-295	13	7	10.5599	CARDINAL
admet-295	13	8	213	CARDINAL
admet-295	14	1	the european union	ORG
admet-295	14	2	eu	ORG
admet-295	14	3	one	CARDINAL
admet-295	14	4	29	CARDINAL
admet-295	14	5	fda	ORG
admet-295	14	6	the european medicines	ORG
admet-295	14	7	ema	ORG
admet-295	15	1	one	CARDINAL
admet-295	15	2	4	CARDINAL
admet-295	17	1	fda	ORG
admet-295	17	2	ema	ORG
admet-295	17	3	1	CARDINAL
admet-295	18	1	ecg	ORG
admet-295	19	1	8	CARDINAL
admet-295	20	1	8-17	CARDINAL
admet-295	21	1	2	CARDINAL
admet-295	21	2	3	DATE
admet-295	21	3	18	CARDINAL
admet-295	24	1	fda	ORG
admet-295	24	2	six	CARDINAL
admet-295	24	3	one	CARDINAL
admet-295	24	4	40	CARDINAL
admet-295	26	1	two	CARDINAL
admet-295	26	2	ates	PERSON
admet-295	27	1	28	CARDINAL
admet-295	27	2	28	CARDINAL
admet-295	27	3	the last 15-years	DATE
admet-295	27	4	2001	DATE
admet-295	27	5	two	CARDINAL
admet-295	27	6	first	ORDINAL
admet-295	27	7	fda	ORG
admet-295	28	1	fda	ORG
admet-295	28	2	fda	ORG
admet-295	28	3	first	ORDINAL
admet-295	28	4	1	CARDINAL
admet-295	29	1	one	CARDINAL
admet-295	29	2	16 (57 %	PERCENT
admet-295	29	3	11.5 years from may 2001 to	DATE
admet-295	29	4	as period 1	CARDINAL
admet-295	29	5	12 (43 %	PERCENT
admet-295	29	6	the last 3.7 years	DATE
admet-295	29	7	october 2012	DATE
admet-295	29	8	2	CARDINAL
admet-295	30	1	1.39	CARDINAL
admet-295	30	2	1	CARDINAL
admet-295	30	3	3.24	CARDINAL
admet-295	30	4	2	CARDINAL
admet-295	31	1	1-3	CARDINAL
admet-295	32	1	rashmi shah admet &	ORG
admet-295	32	2	4(3	CARDINAL
admet-295	32	3	2016	CARDINAL
admet-295	32	4	212	CARDINAL
admet-295	32	5	1	CARDINAL
admet-295	32	6	31	CARDINAL
admet-295	32	7	fda	ORG
admet-295	32	8	eu	PERSON
admet-295	32	9	12 july 2013	DATE
admet-295	32	10	sept. 2013	DATE
admet-295	32	11	11	CARDINAL
admet-295	32	12	dec. 2015	DATE
admet-295	32	13	27 january 2012	DATE
admet-295	32	14	sept. 2012	DATE
admet-295	32	15	sept. 2012 27 march 2013	DATE
admet-295	32	16	29 nov. 2012 21	DATE
admet-295	32	17	march 2014	DATE
admet-295	32	18	29	CARDINAL
admet-295	32	19	april 2014 6	DATE
admet-295	32	20	10 nov. 2015	DATE
admet-295	32	21	20 nov. 2015	DATE
admet-295	32	22	26 august 2011	DATE
admet-295	32	23	23 oct. 2012	TIME
admet-295	32	24	29 may 2013	DATE
admet-295	32	25	26	CARDINAL
admet-295	32	26	august 2013	DATE
admet-295	32	27	28	CARDINAL
admet-295	32	28	june 2006 20 nov. 2006	DATE
admet-295	32	29	18 nov. 2004	DATE
admet-295	32	30	sept. 2005	DATE
admet-295	32	31	5	CARDINAL
admet-295	32	32	june 2009	DATE
admet-295	32	33	13 nov. 2013 21	DATE
admet-295	32	34	oct. 2014	DATE
admet-295	32	35	cll	ORG
admet-295	32	36	waldenström	GPE
admet-295	32	37	10 may 2001	DATE
admet-295	32	38	11 nov. 2001	DATE
admet-295	32	39	mastocytosis	PERSON
admet-295	32	40	lapatinib 13	ORG
admet-295	32	41	10 june 2008	DATE
admet-295	32	42	13 february 2015 28	DATE
admet-295	32	43	29	CARDINAL
admet-295	32	44	october	DATE
admet-295	32	45	19 nov. 2007	DATE
admet-295	33	1	17 october 2014	DATE
admet-295	33	2	15 jan. 2015	DATE
admet-295	33	3	21 nov. 2014	DATE
admet-295	33	4	13 nov. 2015	DATE
admet-295	33	5	2016	CARDINAL
admet-295	33	6	19	CARDINAL
admet-295	33	7	october 2009	DATE
admet-295	33	8	june 2010	DATE
admet-295	33	9	14 dec. 2012	DATE
admet-295	33	10	1 july 2013	DATE
admet-295	33	11	27	CARDINAL
admet-295	33	12	sept. 2012	DATE
admet-295	33	13	26 august 2013	DATE
admet-295	33	14	16 nov. 2011	DATE
admet-295	33	15	august 2012	DATE
admet-295	33	16	20 dec. 2005	DATE
admet-295	33	17	19 july 2006	DATE
admet-295	33	18	26	CARDINAL
admet-295	33	19	january 2006 19	DATE
admet-295	33	20	july 2006	DATE
admet-295	33	21	29 may 2013	DATE
admet-295	33	22	june 2014	DATE
admet-295	33	23	6 april 2011	DATE
admet-295	33	24	17 feb. 2012	DATE
admet-295	33	25	17 august 2011	DATE
admet-295	33	26	17 feb.	DATE
admet-295	34	1	2012	DATE
admet-295	34	2	november 2012	DATE
admet-295	34	3	26	CARDINAL
admet-295	34	4	april 2013	DATE
admet-295	34	5	cll	ORG
admet-295	34	6	4(3	CARDINAL
admet-295	34	7	2016	CARDINAL
admet-295	34	8	212	CARDINAL
admet-295	34	9	10.5599	CARDINAL
admet-295	34	10	215	CARDINAL
admet-295	34	11	ecg	ORG
admet-295	35	1	qtcp	ORG
admet-295	37	1	greater than 500	CARDINAL
admet-295	38	1	41,42	CARDINAL
admet-295	39	1	20 %	PERCENT
admet-295	41	1	about a third	CARDINAL
admet-295	42	1	45	CARDINAL
admet-295	42	2	46	DATE
admet-295	43	1	47	CARDINAL
admet-295	44	1	one	CARDINAL
admet-295	44	2	the last two decades	DATE
admet-295	45	1	apd	PERSON
admet-295	45	2	eads	PERSON
admet-295	45	3	48	CARDINAL
admet-295	47	1	52-56	CARDINAL
admet-295	50	1	57	CARDINAL
admet-295	50	2	172	CARDINAL
admet-295	50	3	550	CARDINAL
admet-295	50	4	29 %	PERCENT
admet-295	50	5	only 4 %	PERCENT
admet-295	52	1	58	CARDINAL
admet-295	55	1	47	CARDINAL
admet-295	55	2	59	CARDINAL
admet-295	56	1	60	CARDINAL
admet-295	56	2	61	DATE
admet-295	57	1	two	CARDINAL
admet-295	58	1	95 %	PERCENT
admet-295	58	2	10	CARDINAL
admet-295	58	3	rashmi shah admet &	ORG
admet-295	58	4	4(3	CARDINAL
admet-295	58	5	2016	CARDINAL
admet-295	58	6	212	CARDINAL
admet-295	58	7	61	CARDINAL
admet-295	59	1	ecg	PRODUCT
admet-295	60	1	first	ORDINAL
admet-295	61	1	2	CARDINAL
admet-295	61	2	11	DATE
admet-295	61	3	39 %	PERCENT
admet-295	61	4	28	CARDINAL
admet-295	62	1	11	CARDINAL
admet-295	62	2	two	CARDINAL
admet-295	63	1	eight (50 %	PERCENT
admet-295	63	2	16	CARDINAL
admet-295	63	3	period 1	DATE
admet-295	63	4	25 %	PERCENT
admet-295	63	5	12	CARDINAL
admet-295	63	6	2	CARDINAL
admet-295	63	7	2	CARDINAL
admet-295	64	1	nontorsadogenic	ORG
admet-295	64	2	6-10	QUANTITY
admet-295	64	3	16-20	CARDINAL
admet-295	64	4	63	CARDINAL
admet-295	65	1	lin	PERSON
admet-295	65	2	19.3	CARDINAL
admet-295	65	3	8.0	CARDINAL
admet-295	65	4	64	CARDINAL
admet-295	66	1	95 %	PERCENT
admet-295	66	2	15	CARDINAL
admet-295	67	1	six	CARDINAL
admet-295	67	2	ceritinib	NORP
admet-295	67	3	13.5	CARDINAL
admet-295	67	4	34.7	CARDINAL
admet-295	67	5	95 %	PERCENT
admet-295	67	6	17.6	CARDINAL
admet-295	67	7	22.2	CARDINAL
admet-295	67	8	22.4	CARDINAL
admet-295	67	9	23.4	CARDINAL
admet-295	67	10	25.8	CARDINAL
admet-295	67	11	36.4	CARDINAL
admet-295	68	1	2,3	CARDINAL
admet-295	70	1	500	CARDINAL
admet-295	70	2	0.5 %	PERCENT
admet-295	70	3	6 %	PERCENT
admet-295	70	4	4.3 %	PERCENT
admet-295	71	1	2	CARDINAL
admet-295	72	1	two	CARDINAL
admet-295	72	2	one	CARDINAL
admet-295	72	3	2	CARDINAL
admet-295	73	1	only 4.4	CARDINAL
admet-295	73	2	95 %	PERCENT
admet-295	73	3	11.2 ms	QUANTITY
admet-295	74	1	65	CARDINAL
admet-295	76	1	4(3	CARDINAL
admet-295	76	2	2016	CARDINAL
admet-295	76	3	212	CARDINAL
admet-295	76	4	10.5599	CARDINAL
admet-295	76	5	217	CARDINAL
admet-295	76	6	2	CARDINAL
admet-295	76	7	1	CARDINAL
admet-295	76	8	may 2001	DATE
admet-295	76	9	september 2012	DATE
admet-295	76	10	16	CARDINAL
admet-295	76	11	2	CARDINAL
admet-295	76	12	october 2012	DATE
admet-295	76	13	may 2016	DATE
admet-295	76	14	12	CARDINAL
admet-295	76	15	 bosutinib *  	TIME
admet-295	76	16	cabozantinib**	PERSON
admet-295	76	17	ceritinib **	PERSON
admet-295	76	18	cobimetinib**	PERSON
admet-295	76	19	dasatinib * 	PERSON
admet-295	77	1		EVENT
admet-295	77	2		ORG
admet-295	77	3		ORG
admet-295	77	4		EVENT
admet-295	77	5		ORG
admet-295	78	1	regorafeniib *	PERSON
admet-295	78	2		ORG
admet-295	80	1	vemurafenib	PERSON
admet-295	80	2	50 %	PERCENT
admet-295	80	3	75 %	PERCENT
admet-295	80	4	63 %	PERCENT
admet-295	80	5	63 %	PERCENT
admet-295	80	6	25 %	PERCENT
admet-295	80	7	58 %	PERCENT
admet-295	80	8	58 %	PERCENT
admet-295	80	9	33 %	PERCENT
admet-295	81	1	period 1	DATE
admet-295	81	2	2	CARDINAL
admet-295	82	1	16	CARDINAL
admet-295	82	2	period 1	DATE
admet-295	82	3	463	CARDINAL
admet-295	82	4	only 20	CARDINAL
admet-295	82	5	3	CARDINAL
admet-295	83	1	14	CARDINAL
admet-295	83	2	35	DATE
admet-295	83	3	57	DATE
admet-295	83	4	246	CARDINAL
admet-295	83	5	only 0	DATE
admet-295	83	6	1	DATE
admet-295	83	7	2	CARDINAL
admet-295	83	8	3	CARDINAL
admet-295	83	9	rashmi shah admet &	ORG
admet-295	83	10	4(3	CARDINAL
admet-295	83	11	2016	CARDINAL
admet-295	83	12	212	CARDINAL
admet-295	84	1	220	CARDINAL
admet-295	85	1	kloth et al	PERSON
admet-295	86	1	66	CARDINAL
admet-295	86	2	363	CARDINAL
admet-295	86	3	vemurafenib	PERSON
admet-295	87	1	ecg	ORG
admet-295	87	2	43 days	DATE
admet-295	88	1	401	CARDINAL
admet-295	88	2	388–415	CARDINAL
admet-295	88	3	415	CARDINAL
admet-295	89	1	33	CARDINAL
admet-295	89	2	9.1 %	PERCENT
admet-295	90	1	only two	CARDINAL
admet-295	90	2	1	CARDINAL
admet-295	90	3	2	CARDINAL
admet-295	90	4	3	CARDINAL
admet-295	90	5	nine	CARDINAL
admet-295	90	6	2.5 %	PERCENT
admet-295	91	1	321	CARDINAL
admet-295	91	2	88.4 %	PERCENT
admet-295	92	1	only five	CARDINAL
admet-295	92	2	1.4 %	PERCENT
admet-295	94	1	one	CARDINAL
admet-295	94	2	apd	PERSON
admet-295	94	3	48-51	CARDINAL
admet-295	96	1	3	CARDINAL
admet-295	97	1	one	CARDINAL
admet-295	97	2	apd	ORG
admet-295	97	3	3,4,5-trisphosphate	CARDINAL
admet-295	98	1	67	CARDINAL
admet-295	98	2	68	CARDINAL
admet-295	99	1	apd	PERSON
admet-295	99	2	69	CARDINAL
admet-295	100	1	one	CARDINAL
admet-295	101	1	one	CARDINAL
admet-295	103	1	70-73	CARDINAL
admet-295	105	1	the us national cancer institute	ORG
admet-295	106	1	74	CARDINAL
admet-295	107	1	two	CARDINAL
admet-295	107	2	ates	PERSON
admet-295	108	1	4(3	CARDINAL
admet-295	108	2	2016	CARDINAL
admet-295	108	3	212	CARDINAL
admet-295	108	4	10.5599	CARDINAL
admet-295	108	5	219	CARDINAL
admet-295	109	1	asymptomatic ecg	ORG
admet-295	109	2	qrs	PRODUCT
admet-295	109	3	75-77	CARDINAL
admet-295	110	1	2	CARDINAL
admet-295	110	2	78-81	CARDINAL
admet-295	111	1	us	GPE
admet-295	113	1	25	CARDINAL
admet-295	113	2	february 2015	DATE
admet-295	113	3	about 14,700	CARDINAL
admet-295	113	4	82	CARDINAL
admet-295	114	1	forty	CARDINAL
admet-295	115	1	european	NORP
admet-295	115	2	1-10 %	PERCENT
admet-295	115	3	82	CARDINAL
admet-295	116	1	one month	DATE
admet-295	119	1	the revised european union	ORG
admet-295	119	2	fda	ORG
admet-295	119	3	29	CARDINAL
admet-295	119	4	april 2016	DATE
admet-295	119	5	83	CARDINAL
admet-295	120	1	17 (	PERCENT
admet-295	120	2	60 %	PERCENT
admet-295	120	3	28	CARDINAL
admet-295	120	4	31	CARDINAL
admet-295	120	5	2016	DATE
admet-295	121	1	10 (63 %	PERCENT
admet-295	121	2	16	CARDINAL
admet-295	121	3	period 1 and 7	DATE
admet-295	121	4	58 %	PERCENT
admet-295	121	5	12	CARDINAL
admet-295	121	6	period 2	DATE
admet-295	122	1	2	CARDINAL
admet-295	122	2	1	CARDINAL
admet-295	122	3	50 % to 25 %	PERCENT
admet-295	122	4	63 % to 58 %	PERCENT
admet-295	123	1	60 %	PERCENT
admet-295	123	2	39 %	PERCENT
admet-295	126	1	as high as	CARDINAL
admet-295	126	2	5-8 %	PERCENT
admet-295	128	1	3	CARDINAL
admet-295	129	1	3	CARDINAL
admet-295	129	2	4	CARDINAL
admet-295	130	1	about 2.8 % and 1.1 %	PERCENT
admet-295	130	2	2.5	CARDINAL
admet-295	130	3	1.5	CARDINAL
admet-295	134	1	four (23 %	PERCENT
admet-295	134	2	17	CARDINAL
admet-295	134	3	rashmi shah admet &	ORG
admet-295	134	4	4(3	CARDINAL
admet-295	134	5	2016	CARDINAL
admet-295	134	6	212	CARDINAL
admet-295	136	1	yang	PERSON
admet-295	136	2	fda	ORG
admet-295	136	3	85	CARDINAL
admet-295	139	1	4-week	DATE
admet-295	139	2	86	CARDINAL
admet-295	139	3	87	CARDINAL
admet-295	140	1	30 mg/kg	QUANTITY
admet-295	140	2	88	CARDINAL
admet-295	141	1	89	CARDINAL
admet-295	141	2	90	CARDINAL
admet-295	144	1	91	CARDINAL
admet-295	145	1	3	CARDINAL
admet-295	146	1	ates	PERSON
admet-295	147	1	ten (63 %	PERCENT
admet-295	147	2	16	CARDINAL
admet-295	147	3	1	CARDINAL
admet-295	147	4	dasatinib	PERSON
admet-295	148	1	12	CARDINAL
admet-295	148	2	period 2	DATE
admet-295	148	3	four	DATE
admet-295	148	4	33 %	PERCENT
admet-295	148	5	ates	PERSON
admet-295	148	6	cabozantinib	PERSON
admet-295	149	1	3	CARDINAL
admet-295	150	1	ates	PERSON
admet-295	150	2	cva	ORG
admet-295	151	1	5 %	PERCENT
admet-295	151	2	2.5 %	PERCENT
admet-295	151	3	2 %	PERCENT
admet-295	151	4	2 %	PERCENT
admet-295	151	5	0.8 %	PERCENT
admet-295	151	6	0 %	PERCENT
admet-295	152	1	2.2%	PERCENT
admet-295	153	1	1.5 %	PERCENT
admet-295	153	2	0.4 %	PERCENT
admet-295	154	1	3	CARDINAL
admet-295	154	2	3 %	PERCENT
admet-295	154	3	1 %	PERCENT
admet-295	155	1	one	CARDINAL
admet-295	155	2	10,255	CARDINAL
admet-295	155	3	1.4 %	PERCENT
admet-295	155	4	95 %	PERCENT
admet-295	155	5	1.2–1.6	CARDINAL
admet-295	156	1	23	CARDINAL
admet-295	157	1	9,711	CARDINAL
admet-295	157	2	19	CARDINAL
admet-295	157	3	ates	ORG
admet-295	157	4	1.5 %	PERCENT
admet-295	157	5	95 %	PERCENT
admet-295	157	6	1.0–2.3	CARDINAL
admet-295	157	7	4(3	CARDINAL
admet-295	157	8	2016	CARDINAL
admet-295	157	9	212	CARDINAL
admet-295	157	10	10.5599	CARDINAL
admet-295	157	11	221	CARDINAL
admet-295	158	1	24	CARDINAL
admet-295	159	1	ates	PERSON
admet-295	159	2	67.4 %	PERCENT
admet-295	159	3	7.9 %	PERCENT
admet-295	159	4	cva	GPE
admet-295	159	5	6.7 %	PERCENT
admet-295	160	1	2.26	CARDINAL
admet-295	160	2	95 %	PERCENT
admet-295	160	3	1.38–3.68	CARDINAL
admet-295	160	4	0.001	CARDINAL
admet-295	160	5	0.70	CARDINAL
admet-295	160	6	0.32	CARDINAL
admet-295	160	7	0.76	CARDINAL
admet-295	160	8	0.37	CARDINAL
admet-295	160	9	0.89	CARDINAL
admet-295	161	1	about 1.50 %	PERCENT
admet-295	161	2	2.6	CARDINAL
admet-295	164	1	92	CARDINAL
admet-295	164	2	three	CARDINAL
admet-295	165	1	128,415	CARDINAL
admet-295	166	1	1,642	CARDINAL
admet-295	166	2	1.1 %	PERCENT
admet-295	166	3	0.7 %	PERCENT
admet-295	166	4	cva	GPE
admet-295	166	5	1,184	CARDINAL
admet-295	166	6	72.1 %	PERCENT
admet-295	167	1	61 %	PERCENT
admet-295	167	2	73 %	PERCENT
admet-295	167	3	cva	ORG
admet-295	169	1	3.3 %	PERCENT
admet-295	169	2	0.5 %	PERCENT
admet-295	169	3	1.2 %	PERCENT
admet-295	169	4	0.5 %	PERCENT
admet-295	169	5	cva	GPE
admet-295	170	1	72.5 %	PERCENT
admet-295	170	2	72.0 %	PERCENT
admet-295	172	1	jang et al	PERSON
admet-295	173	1	93	CARDINAL
admet-295	173	2	171	CARDINAL
admet-295	173	3	26 %	PERCENT
admet-295	173	4	670	CARDINAL
admet-295	173	5	65 years	DATE
admet-295	174	1	0.87	CARDINAL
admet-295	174	2	0.14	CARDINAL
admet-295	174	3	0.14	CARDINAL
admet-295	174	4	1000	CARDINAL
admet-295	175	1	1.38	CARDINAL
admet-295	175	2	95 %	PERCENT
admet-295	175	3	1.02-1.87	CARDINAL
admet-295	175	4	2.84	CARDINAL
admet-295	175	5	95 %	PERCENT
admet-295	175	6	1.52-5.31	CARDINAL
admet-295	175	7	788	CARDINAL
admet-295	176	1	first	ORDINAL
admet-295	176	2	december 2012	DATE
admet-295	176	3	94	CARDINAL
admet-295	177	1	fifty-one	CARDINAL
admet-295	177	2	11 %	PERCENT
admet-295	177	3	449	CARDINAL
admet-295	178	1	21	CARDINAL
admet-295	178	2	5 %	PERCENT
admet-295	180	1	34	CARDINAL
admet-295	180	2	8 %	PERCENT
admet-295	180	3	449	CARDINAL
admet-295	180	4	21	CARDINAL
admet-295	181	1	thirty	CARDINAL
admet-295	181	2	34	CARDINAL
admet-295	181	3	one	CARDINAL
admet-295	183	1	fda	ORG
admet-295	183	2	at least 12 months	DATE
admet-295	183	3	95	CARDINAL
admet-295	184	1	just over 10 months later	DATE
admet-295	184	2	31	CARDINAL
admet-295	184	3	october 2013	DATE
admet-295	184	4	approximately 24 %	PERCENT
admet-295	184	5	one	CARDINAL
admet-295	184	6	1.3 years	DATE
admet-295	184	7	approximately 48 %	PERCENT
admet-295	184	8	2.7 years	DATE
admet-295	184	9	96	CARDINAL
admet-295	185	1	rashmi shah admet &	ORG
admet-295	185	2	4(3	CARDINAL
admet-295	185	3	2016	CARDINAL
admet-295	185	4	212	CARDINAL
admet-295	186	1	as early as 2 weeks	DATE
admet-295	188	1	fda	ORG
admet-295	188	2	96	CARDINAL
admet-295	189	1	fda	ORG
admet-295	189	2	20 december 2013	DATE
admet-295	189	3	97	CARDINAL
admet-295	190	1	fda	ORG
admet-295	191	1	2	CARDINAL
admet-295	191	2	june 2016	DATE
admet-295	192	1	98	CARDINAL
admet-295	192	2	18 %	PERCENT
admet-295	192	3	33 %	PERCENT
admet-295	192	4	56 %	PERCENT
admet-295	192	5	50-74	CARDINAL
admet-295	192	6	75 years	DATE
admet-295	192	7	12 %	PERCENT
admet-295	192	8	18 %	PERCENT
admet-295	192	9	46 %	PERCENT
admet-295	193	1	24 %	PERCENT
admet-295	193	2	20 %	PERCENT
admet-295	195	1	45mg	QUANTITY
admet-295	195	2	daily	DATE
admet-295	195	3	94	CARDINAL
admet-295	195	4	98	CARDINAL
admet-295	196	1	ates	PERSON
admet-295	198	1	three	CARDINAL
admet-295	198	2	99	CARDINAL
admet-295	198	3	3	CARDINAL
admet-295	198	4	12,870	CARDINAL
admet-295	198	5	11,114	CARDINAL
admet-295	198	6	1.50-2.26 %	PERCENT
admet-295	198	7	1.64-2.23	CARDINAL
admet-295	199	1	cabozantinib	PERSON
admet-295	202	1	yang et al	PERSON
admet-295	203	1	102	CARDINAL
admet-295	203	2	1.75	CARDINAL
admet-295	207	1	schutz et al	PERSON
admet-295	208	1	100	CARDINAL
admet-295	208	2	hong et al	GPE
admet-295	209	1	101	CARDINAL
admet-295	210	1	yang et al	PERSON
admet-295	211	1	102	CARDINAL
admet-295	211	2	3.3 %	PERCENT
admet-295	211	3	4(3	CARDINAL
admet-295	211	4	2016	CARDINAL
admet-295	211	5	212	CARDINAL
admet-295	211	6	10.5599	CARDINAL
admet-295	211	7	223	CARDINAL
admet-295	212	1	jean et al	PERSON
admet-295	213	1	103	CARDINAL
admet-295	215	1	3	CARDINAL
admet-295	216	1	three	CARDINAL
admet-295	216	2	95%	PERCENT
admet-295	217	1	sivendran et al	PERSON
admet-295	218	1	2,762	CARDINAL
admet-295	218	2	2,401	CARDINAL
admet-295	218	3	sunitinib sorafenib pazopanib vandetanib rr	PERSON
admet-295	219	1	1.64	CARDINAL
admet-295	219	2	1.16	CARDINAL
admet-295	219	3	2.32	CARDINAL
admet-295	219	4	0.01 2.26	CARDINAL
admet-295	219	5	1.26	CARDINAL
admet-295	219	6	99	CARDINAL
admet-295	220	1	2,461	CARDINAL
admet-295	220	2	2,218	CARDINAL
admet-295	220	3	sunitinib sorafenib pazopanib rr	PERSON
admet-295	221	1	2.23	CARDINAL
admet-295	221	2	1.12	CARDINAL
admet-295	221	3	4.44	CARDINAL
admet-295	221	4	0.023 1.50	CARDINAL
admet-295	222	1	100	CARDINAL
admet-295	222	2	hong et al	GPE
admet-295	223	1	7,644 6,495	CARDINAL
admet-295	223	2	cabozantinib lapatinib pazopanib regorafenib sunitinib sorafenib vandetanib	PERSON
admet-295	223	3	1.85	CARDINAL
admet-295	223	4	1.33	CARDINAL
admet-295	223	5	2.58	CARDINAL
admet-295	223	6	0.01 1.90	CARDINAL
admet-295	224	1	101	CARDINAL
admet-295	225	1	104	CARDINAL
admet-295	225	2	7,508	CARDINAL
admet-295	225	3	two	CARDINAL
admet-295	225	4	6,317	CARDINAL
admet-295	226	1	1.9 %	PERCENT
admet-295	226	2	95 %	PERCENT
admet-295	226	3	1.2 2.9	CARDINAL
admet-295	226	4	0.99 (	PERCENT
admet-295	226	5	95 %	PERCENT
admet-295	226	6	0.70 1.41	CARDINAL
admet-295	226	7	0.97	CARDINAL
admet-295	230	1	43	CARDINAL
admet-295	230	2	16,011	CARDINAL
admet-295	230	3	8,460	CARDINAL
admet-295	230	4	7,551	CARDINAL
admet-295	231	1	105	CARDINAL
admet-295	231	2	two	CARDINAL
admet-295	231	3	cabozantinib	PERSON
admet-295	232	1	0.82	CARDINAL
admet-295	232	2	9 5%	PERCENT
admet-295	232	3	0.76–0.89	CARDINAL
admet-295	232	4	0.99	CARDINAL
admet-295	232	5	95 %	PERCENT
admet-295	232	6	0.95–1.03	DATE
admet-295	233	1	1.63	CARDINAL
admet-295	233	2	95 %	PERCENT
admet-295	233	3	1.32	CARDINAL
admet-295	233	4	2.01	CARDINAL
admet-295	233	5	1.80	CARDINAL
admet-295	233	6	95 %	PERCENT
admet-295	233	7	1.58–2.06	CARDINAL
admet-295	233	8	1.25	CARDINAL
admet-295	233	9	95 %	PERCENT
admet-295	233	10	1.16–1.36	CARDINAL
admet-295	234	1	1.49 (	PERCENT
admet-295	234	2	95 %	PERCENT
admet-295	234	3	1.16-1.90	CARDINAL
admet-295	234	4	rashmi shah admet &	ORG
admet-295	234	5	4(3	CARDINAL
admet-295	234	6	2016	CARDINAL
admet-295	234	7	212	CARDINAL
admet-295	234	8	231 224	CARDINAL
admet-295	234	9	2.04	CARDINAL
admet-295	234	10	95 %	PERCENT
admet-295	234	11	1.38-3.01	CARDINAL
admet-295	237	1	106	CARDINAL
admet-295	239	1	one	CARDINAL
admet-295	239	2	switzerland	GPE
admet-295	239	3	985	CARDINAL
admet-295	239	4	1,737	CARDINAL
admet-295	239	5	32.4 %	PERCENT
admet-295	239	6	at least one	CARDINAL
admet-295	239	7	27.2 %	PERCENT
admet-295	239	8	107	CARDINAL
admet-295	240	1	seruga et al	ORG
admet-295	241	1	108	CARDINAL
admet-295	242	1	one	CARDINAL
admet-295	242	2	japan	GPE
admet-295	242	3	111	CARDINAL
admet-295	242	4	eight	CARDINAL
admet-295	242	5	only 28	CARDINAL
admet-295	242	6	25.0 %	PERCENT
admet-295	242	7	22	CARDINAL
admet-295	242	8	19.6 %	PERCENT
admet-295	242	9	japanese	NORP
admet-295	242	10	58	DATE
admet-295	242	11	52.3 %	PERCENT
admet-295	242	12	first	ORDINAL
admet-295	242	13	109	CARDINAL
admet-295	244	1	14	CARDINAL
admet-295	250	1	110	CARDINAL
admet-295	252	1	111	CARDINAL
admet-295	254	1	114	CARDINAL
admet-295	255	1	4(3	CARDINAL
admet-295	255	2	2016	CARDINAL
admet-295	255	3	212	CARDINAL
admet-295	255	4	10.5599	CARDINAL
admet-295	255	5	225	CARDINAL
admet-295	255	6	112	CARDINAL
admet-295	255	7	120	CARDINAL
admet-295	256	1	1999	DATE
admet-295	256	2	46	CARDINAL
admet-295	256	3	121	CARDINAL
admet-295	259	1	nineteen	DATE
admet-295	259	2	68 %	PERCENT
admet-295	259	3	28	CARDINAL
admet-295	259	4	five	CARDINAL
admet-295	259	5	2	CARDINAL
admet-295	260	1	twelve (75 %	PERCENT
admet-295	260	2	16	CARDINAL
admet-295	260	3	period 1 and 7	DATE
admet-295	260	4	58 %	PERCENT
admet-295	260	5	12	CARDINAL
admet-295	260	6	2	CARDINAL
admet-295	261	1	four	CARDINAL
admet-295	261	2	12	CARDINAL
admet-295	261	3	one	CARDINAL
admet-295	261	4	7	CARDINAL
admet-295	261	5	2	CARDINAL
admet-295	264	1	two	CARDINAL
admet-295	264	2	approximately 10 percent	PERCENT
admet-295	264	3	122	CARDINAL
admet-295	264	4	123	CARDINAL
admet-295	265	1	one	CARDINAL
admet-295	265	2	two	CARDINAL
admet-295	266	1	124	CARDINAL
admet-295	269	1	248	CARDINAL
admet-295	269	2	27.5 months	DATE
admet-295	269	3	125	CARDINAL
admet-295	274	1	3	CARDINAL
admet-295	276	1	rashmi shah admet &	ORG
admet-295	276	2	4(3	CARDINAL
admet-295	276	3	2016	CARDINAL
admet-295	276	4	212	CARDINAL
admet-295	277	1	december 2004	DATE
admet-295	277	2	london	GPE
admet-295	277	3	uk	GPE
admet-295	279	1	1	CARDINAL
admet-295	279	2	r. r. shah	PERSON
admet-295	279	3	s. a. roberts	PERSON
admet-295	279	4	d. r. shah	PERSON
admet-295	281	1	j. clin	PERSON
admet-295	283	1	2013	DATE
admet-295	283	2	396	CARDINAL
admet-295	284	1	2	CARDINAL
admet-295	284	2	r. r. shah	PERSON
admet-295	284	3	j. morganroth	PERSON
admet-295	284	4	d. r. shah	PERSON
admet-295	284	5	36(5	CARDINAL
admet-295	284	6	2013	DATE
admet-295	284	7	295	CARDINAL
admet-295	285	1	3	CARDINAL
admet-295	285	2	r. r. shah	PERSON
admet-295	285	3	j. morganroth	PERSON
admet-295	286	1	38(8	CARDINAL
admet-295	286	2	2015	CARDINAL
admet-295	286	3	693	CARDINAL
admet-295	287	1	4	CARDINAL
admet-295	287	2	j. zhang	PERSON
admet-295	287	3	l. zhang	PERSON
admet-295	287	4	y. wang	PERSON
admet-295	287	5	g. zhao	PERSON
admet-295	290	1	2016	CARDINAL
admet-295	290	2	905	CARDINAL
admet-295	291	1	5	CARDINAL
admet-295	291	2	m. rask-andersen	PERSON
admet-295	291	3	j. zhang	PERSON
admet-295	291	4	d.	NORP
admet-295	291	5	h. b. schiöth	PERSON
admet-295	293	1	sci	ORG
admet-295	294	1	2014	DATE
admet-295	294	2	604	CARDINAL
admet-295	295	1	6	CARDINAL
admet-295	295	2	t. e. nielsen	PERSON
admet-295	295	3	m. h. clausen	PERSON
admet-295	296	1	today	DATE
admet-295	296	2	21(1	CARDINAL
admet-295	296	3	2016	CARDINAL
admet-295	296	4	5	CARDINAL
admet-295	297	1	7	CARDINAL
admet-295	297	2	k. l. miller	PERSON
admet-295	297	3	m. lanthier	PERSON
admet-295	298	1	nat	PERSON
admet-295	300	1	2015	CARDINAL
admet-295	300	2	83	DATE
admet-295	301	1	8	CARDINAL
admet-295	301	2	d. r. shah	PERSON
admet-295	301	3	r. r. shah	PERSON
admet-295	301	4	j. morganroth	PERSON
admet-295	302	1	36(6	CARDINAL
admet-295	302	2	2013	DATE
admet-295	302	3	413	CARDINAL
admet-295	303	1	9	CARDINAL
admet-295	303	2	r. dienstmann	PERSON
admet-295	303	3	i. braña	PERSON
admet-295	303	4	j. rodon	PERSON
admet-295	303	5	j. tabernero	PERSON
admet-295	304	1	2011	DATE
admet-295	305	1	10	CARDINAL
admet-295	305	2	f. di fiore	PERSON
admet-295	305	3	o. rigal	PERSON
admet-295	305	4	c. ménager	PERSON
admet-295	305	5	p. michel	PERSON
admet-295	305	6	c. pfister	PERSON
admet-295	307	1	j. cancer	PERSON
admet-295	307	2	105(12	CARDINAL
admet-295	307	3	2011	DATE
admet-295	307	4	1811-1813	DATE
admet-295	308	1	11	CARDINAL
admet-295	308	2	h. y. small,	PERSON
admet-295	308	3	a. c. montezano	PERSON
admet-295	308	4	f. j. rios	PERSON
admet-295	308	5	c. savoia	PERSON
admet-295	308	6	r. m. touyz	PERSON
admet-295	309	1	j. cardiol	PERSON
admet-295	310	1	2014	DATE
admet-295	310	2	534	CARDINAL
admet-295	311	1	12	CARDINAL
admet-295	311	2	s. liu	PERSON
admet-295	311	3	r. kurzrock	PERSON
admet-295	312	1	semin	PERSON
admet-295	314	1	42(6	CARDINAL
admet-295	314	2	2015	CARDINAL
admet-295	314	3	863	CARDINAL
admet-295	315	1	13	CARDINAL
admet-295	315	2	m. schmidinger	PERSON
admet-295	315	3	m. vogl	PERSON
admet-295	315	4	m. bojic	PERSON
admet-295	315	5	w. lamm	PERSON
admet-295	315	6	h. heinzl	GPE
admet-295	315	7	a. haitel	PERSON
admet-295	315	8	m. clodi	PERSON
admet-295	315	9	g. kramer	PERSON
admet-295	315	10	c. c. zielinski	PERSON
admet-295	316	1	117(3	DATE
admet-295	316	2	2011	DATE
admet-295	316	3	534	CARDINAL
admet-295	317	1	14	CARDINAL
admet-295	317	2	a. nearchou	PERSON
admet-295	317	3	a. valachis	PERSON
admet-295	317	4	o. akre	PERSON
admet-295	318	1	clin	PERSON
admet-295	318	2	genitourin	PERSON
admet-295	319	1	13(4	CARDINAL
admet-295	319	2	2015) 280286	DATE
admet-295	320	1	15	CARDINAL
admet-295	320	2	e. b. bailey	PERSON
admet-295	320	3	s. k. tantravahi	PERSON
admet-295	320	4	a. poole	PERSON
admet-295	320	5	a. m. agarwal	PERSON
admet-295	320	6	a. m. straubhar	PERSON
admet-295	320	7	j. a. batten	PERSON
admet-295	320	8	s. b. patel	PERSON
admet-295	320	9	c. e. wells	PERSON
admet-295	320	10	d. d.	NORP
admet-295	320	11	n. agarwal	PERSON
admet-295	321	1	clin	PERSON
admet-295	321	2	genitourin	PERSON
admet-295	322	1	13(3	CARDINAL
admet-295	322	2	2015	CARDINAL
admet-295	323	1	137	CARDINAL
admet-295	324	1	16	CARDINAL
admet-295	324	2	g. lombardi	PERSON
admet-295	324	3	f. zustovich	PERSON
admet-295	324	4	p. farina	PERSON
admet-295	324	5	a. della puppa	PERSON
admet-295	324	6	v. polo	PERSON
admet-295	324	7	r. bertorelle	PERSON
admet-295	324	8	m. p. gardiman	PERSON
admet-295	324	9	a. banzato	PERSON
admet-295	324	10	ciccarino	GPE
admet-295	324	11	l. denaro	PERSON
admet-295	325	1	24(1	CARDINAL
admet-295	325	2	2013	DATE
admet-295	325	3	90-97	CARDINAL
admet-295	326	1	17	CARDINAL
admet-295	326	2	a. poprach	PERSON
admet-295	326	3	t. pavlik	PERSON
admet-295	326	4	b. melichar	PERSON
admet-295	326	5	i. puzanov	PERSON
admet-295	326	6	l. dusek	PERSON
admet-295	326	7	z. bortlicek	PERSON
admet-295	326	8	r. vyzula	PERSON
admet-295	326	9	j. abrahamova	PERSON
admet-295	326	10	t. buchler	PERSON
admet-295	326	11	czech	NORP
admet-295	327	1	ann	PERSON
admet-295	328	1	23(12	CARDINAL
admet-295	328	2	2012	DATE
admet-295	328	3	3137-3143	CARDINAL
admet-295	329	1	18	CARDINAL
admet-295	329	2	r. b. cohen	PERSON
admet-295	329	3	s. oudard	PERSON
admet-295	331	1	30(5	CARDINAL
admet-295	331	2	2012	DATE
admet-295	331	3	2066-2079	DATE
admet-295	332	1	19	CARDINAL
admet-295	333	1	ejc suppl	PERSON
admet-295	334	1	11(2	CARDINAL
admet-295	334	2	2013	DATE
admet-295	334	3	172	CARDINAL
admet-295	335	1	20	CARDINAL
admet-295	335	2	w. x. qi	PERSON
admet-295	335	3	a. n.	PERSON
admet-295	336	1	z. shen	PERSON
admet-295	336	2	y. yao	PERSON
admet-295	338	1	j. clin	PERSON
admet-295	340	1	2013	DATE
admet-295	340	2	348	CARDINAL
admet-295	341	1	21	CARDINAL
admet-295	341	2	c. j. morgan	PERSON
admet-295	341	3	y. je	ORG
admet-295	341	4	p. l. nguyen	PERSON
admet-295	341	5	q. d. trinh	PERSON
admet-295	341	6	t. k. choueiri	PERSON
admet-295	343	1	rev	PERSON
admet-295	343	2	oncol	TIME
admet-295	344	1	2015	CARDINAL
admet-295	344	2	228	CARDINAL
admet-295	345	1	22	CARDINAL
admet-295	345	2	w. x. qi	PERSON
admet-295	345	3	z. shen	PERSON
admet-295	345	4	l. n. tang	PERSON
admet-295	347	1	j. clin	PERSON
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admet-295	350	1	23	CARDINAL
admet-295	350	2	t. k. choueiri	PERSON
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admet-295	351	1	j. clin	PERSON
admet-295	352	1	oncol	TIME
admet-295	353	1	2010	DATE
admet-295	353	2	2280-2285	DATE
admet-295	354	1	24	CARDINAL
admet-295	354	2	w. x. qi	PERSON
admet-295	354	3	z. shen	PERSON
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admet-295	356	1	rev	PERSON
admet-295	356	2	oncol	TIME
admet-295	357	1	2014	DATE
admet-295	357	2	71	CARDINAL
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admet-295	358	2	w. x. qi	PERSON
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admet-295	360	3	2013	DATE
admet-295	361	1	26	CARDINAL
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admet-295	363	1	rev	PERSON
admet-295	363	2	oncol	TIME
admet-295	364	1	87(1	DATE
admet-295	364	2	2013	DATE
admet-295	364	3	80-89	DATE
admet-295	365	1	27	CARDINAL
admet-295	365	2	w. x. qi	PERSON
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admet-295	366	2	oncol.	DATE
admet-295	367	1	2013	DATE
admet-295	367	2	2943	CARDINAL
admet-295	368	1	28	CARDINAL
admet-295	368	2	j. bellmunt	PERSON
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admet-295	370	1	oncol	TIME
admet-295	371	1	14(4	CARDINAL
admet-295	371	2	2012	DATE
admet-295	371	3	295	CARDINAL
admet-295	372	1	29	CARDINAL
admet-295	372	2	r. r. shah	PERSON
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admet-295	373	2	2013	DATE
admet-295	373	3	491	CARDINAL
admet-295	374	1	4(3	CARDINAL
admet-295	374	2	2016	CARDINAL
admet-295	374	3	212	CARDINAL
admet-295	374	4	10.5599	CARDINAL
admet-295	374	5	227	CARDINAL
admet-295	375	1	30	CARDINAL
admet-295	375	2	r. iacovelli	PERSON
admet-295	375	3	a. palazzo	PERSON
admet-295	375	4	g. procopio	PERSON
admet-295	375	5	m. santoni	PERSON
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admet-295	375	7	a. de benedetto	PERSON
admet-295	375	8	s. mezi	PERSON
admet-295	375	9	e. cortesi	PERSON
admet-295	377	1	j. clin	PERSON
admet-295	379	1	2014	DATE
admet-295	379	2	929	CARDINAL
admet-295	380	1	31	CARDINAL
admet-295	380	2	y je	PERSON
admet-295	380	3	n. e. mouallem	PERSON
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admet-295	380	6	t. k. choueiri	PERSON
admet-295	382	1	rev	PERSON
admet-295	382	2	oncol	TIME
admet-295	383	1	2015	CARDINAL
admet-295	383	2	257	CARDINAL
admet-295	384	1	32	CARDINAL
admet-295	384	2	w. x. qi	PERSON
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admet-295	386	1	27(1	CARDINAL
admet-295	386	2	2015	CARDINAL
admet-295	386	3	40-51	CARDINAL
admet-295	387	1	33	CARDINAL
admet-295	387	2	o. abdel-rahman	PERSON
admet-295	387	3	h. elhalawani	PERSON
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admet-295	389	2	1109-1122	CARDINAL
admet-295	390	1	34	CARDINAL
admet-295	390	2	r. massey	PERSON
admet-295	390	3	j. s. okman	PERSON
admet-295	390	4	j. wilkerson	PERSON
admet-295	390	5	e. w. cowen	PERSON
admet-295	391	1	23(6	CARDINAL
admet-295	391	2	2015	CARDINAL
admet-295	391	3	1827-1835	DATE
admet-295	392	1	35	CARDINAL
admet-295	392	2	o. abdel-rahman	PERSON
admet-295	392	3	m. fouad.	PERSON
admet-295	394	1	2014	DATE
admet-295	394	2	1063	CARDINAL
admet-295	395	1	36	CARDINAL
admet-295	395	2	t. wang	PERSON
admet-295	395	3	l-h liu	DATE
admet-295	396	1	plos	PERSON
admet-295	397	1	one 9(3	DATE
admet-295	397	2	2014	DATE
admet-295	398	1	37	CARDINAL
admet-295	398	2	s. r. hayman	PERSON
admet-295	398	3	n. leung	PERSON
admet-295	398	4	j. p. grande	PERSON
admet-295	398	5	d. garovic	PERSON
admet-295	399	1	curr	PERSON
admet-295	399	2	oncol	TIME
admet-295	400	1	14(4	CARDINAL
admet-295	400	2	2012	DATE
admet-295	400	3	285	CARDINAL
admet-295	401	1	38	CARDINAL
admet-295	401	2	s. l. kurtz	PERSON
admet-295	401	3	c. m. barysauskas	PERSON
admet-295	401	4	a. p. pilotte	PERSON
admet-295	401	5	a. j. wagner	PERSON
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admet-295	402	1	oncol.	DATE
admet-295	403	1	51(11	CARDINAL
admet-295	403	2	2015	CARDINAL
admet-295	403	3	1026-1033	CARDINAL
admet-295	404	1	39	CARDINAL
admet-295	404	2	c. j. morgan	PERSON
admet-295	404	3	t. k. choueiri	PERSON
admet-295	404	4	p. rocha	PERSON
admet-295	404	5	g. naik	PERSON
admet-295	406	1	rev	PERSON
admet-295	406	2	oncol	TIME
admet-295	407	1	94(1	CARDINAL
admet-295	407	2	2015	CARDINAL
admet-295	407	3	136	CARDINAL
admet-295	408	1	40	CARDINAL
admet-295	409	1	march 2005	DATE
admet-295	410	1	food and drug administration	ORG
admet-295	410	2	rockville	GPE
admet-295	410	3	md 20857	GPE
admet-295	410	4	usa.	GPE
admet-295	410	5	1	CARDINAL
admet-295	411	1	41	CARDINAL
admet-295	411	2	g. michels	PERSON
admet-295	411	3	m. kochanek	PERSON
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admet-295	413	1	klin	ORG
admet-295	415	1	2015	CARDINAL
admet-295	417	1	42	CARDINAL
admet-295	417	2	w. haverkamp	PERSON
admet-295	417	3	g. breithardt	PERSON
admet-295	417	4	a. j. camm	PERSON
admet-295	417	5	m. j. janse	PERSON
admet-295	417	6	m. r. rosen	PERSON
admet-295	417	7	c. antzelevitch	PERSON
admet-295	417	8	d. escande	GPE
admet-295	417	9	m. franz	PERSON
admet-295	417	10	m. malik	PERSON
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admet-295	417	12	r. shah	PERSON
admet-295	418	1	cardiovasc	ORG
admet-295	420	1	47(2	CARDINAL
admet-295	420	2	2000	CARDINAL
admet-295	420	3	219	CARDINAL
admet-295	421	1	43	CARDINAL
admet-295	421	2	j. l. rey	PERSON
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admet-295	422	1	ann	PERSON
admet-295	423	1	cardiol	PERSON
admet-295	424	1	angeiol	PERSON
admet-295	425	1	paris	GPE
admet-295	426	1	1985	DATE
admet-295	426	2	381	CARDINAL
admet-295	427	1	french	NORP
admet-295	428	1	44	CARDINAL
admet-295	428	2	d. k. wysowski	PERSON
admet-295	428	3	a. corken	PERSON
admet-295	428	4	h. gallo-torres	PERSON
admet-295	428	5	l. talarico	PERSON
admet-295	428	6	e. m. rodriguez.	PERSON
admet-295	429	1	j. gastroenterol	PERSON
admet-295	430	1	96(6	CARDINAL
admet-295	430	2	2001	DATE
admet-295	430	3	1698	CARDINAL
admet-295	431	1	45	CARDINAL
admet-295	431	2	r. r. shah	PERSON
admet-295	432	1	7(6	DATE
admet-295	432	2	2006	DATE
admet-295	432	3	889	CARDINAL
admet-295	433	1	46	CARDINAL
admet-295	433	2	n. stockbridge	PERSON
admet-295	433	3	j. morganroth	PERSON
admet-295	433	4	r. r. shah	PERSON
admet-295	433	5	c. garnett	PERSON
admet-295	433	6	36(3	CARDINAL
admet-295	433	7	2013	DATE
admet-295	433	8	167	CARDINAL
admet-295	434	1	47	CARDINAL
admet-295	434	2	r. r. shah	PERSON
admet-295	435	1	30(12	CARDINAL
admet-295	435	2	2007	DATE
admet-295	435	3	1093	CARDINAL
admet-295	436	1	48	CARDINAL
admet-295	436	2	l. johannesen	PERSON
admet-295	436	3	j. vicente	PERSON
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admet-295	436	5	c. erato	PERSON
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admet-295	436	7	k. waite-labott	PERSON
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admet-295	436	9	j. lin	PERSON
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admet-295	436	11	a. mutlib	PERSON
admet-295	436	12	j. wang	PERSON
admet-295	436	13	w. j. crumb	PERSON
admet-295	436	14	k. blinova	PERSON
admet-295	436	15	d. chan	PERSON
admet-295	436	16	j. stohlman	PERSON
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admet-295	436	19	n. stockbridge	PERSON
admet-295	436	20	d. g. strauss.	PERSON
admet-295	437	1	clin	PERSON
admet-295	440	1	99(2	CARDINAL
admet-295	440	2	2016	CARDINAL
admet-295	440	3	214	CARDINAL
admet-295	440	4	223	CARDINAL
admet-295	441	1	49	CARDINAL
admet-295	441	2	m. c. makielski	PERSON
admet-295	442	1	26(2	CARDINAL
admet-295	442	2	2016	CARDINAL
admet-295	442	3	115	CARDINAL
admet-295	443	1	50	CARDINAL
admet-295	443	2	z. j. huang	PERSON
admet-295	443	3	d. z. dai	PERSON
admet-295	443	4	n. li	PERSON
admet-295	443	5	t. na	GPE
admet-295	443	6	m. ji	PERSON
admet-295	443	7	y. dai	PERSON
admet-295	444	1	clin	PERSON
admet-295	445	1	physiol	PERSON
admet-295	446	1	34(4	CARDINAL
admet-295	446	2	2007	DATE
admet-295	446	3	310	CARDINAL
admet-295	447	1	51	CARDINAL
admet-295	447	2	l. johannesen	PERSON
admet-295	447	3	j. vicente	PERSON
admet-295	447	4	j. w. mason	PERSON
admet-295	447	5	c. sanabria	PERSON
admet-295	447	6	k. waite-labott	PERSON
admet-295	447	7	m. hong	PERSON
admet-295	447	8	p. guo	PERSON
admet-295	447	9	j. lin	PERSON
admet-295	447	10	j. s. sørensen	PERSON
admet-295	447	11	l. galeotti	PERSON
admet-295	447	12	j. florian	PERSON
admet-295	447	13	m. ugander	PERSON
admet-295	447	14	n. stockbridge	PERSON
admet-295	447	15	d. g. strauss.	PERSON
admet-295	448	1	clin	PERSON
admet-295	451	1	2014	DATE
admet-295	451	2	549	CARDINAL
admet-295	452	1	52	CARDINAL
admet-295	452	2	g. antoons	PERSON
admet-295	452	3	a. oros	PERSON
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admet-295	455	1	55(8	CARDINAL
admet-295	455	2	2010	DATE
admet-295	455	3	801	CARDINAL
admet-295	456	1	53	CARDINAL
admet-295	456	2	s. jia	PERSON
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admet-295	458	1	j. pharmacol	PERSON
admet-295	459	1	164(2	CARDINAL
admet-295	459	2	2011	DATE
admet-295	459	3	308	CARDINAL
admet-295	460	1	54	CARDINAL
admet-295	460	2	m. k. murawsky	PERSON
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admet-295	460	4	e. w. lewis	PERSON
admet-295	461	1	j. pharmacol	ORG
admet-295	464	1	286(2	PERSON
admet-295	464	2	1998	DATE
admet-295	464	3	788	CARDINAL
admet-295	465	1	55	CARDINAL
admet-295	465	2	l. eckardt	PERSON
admet-295	465	3	g. breithardt	PERSON
admet-295	465	4	w. haverkamp	PERSON
admet-295	466	1	j. pharmacol	ORG
admet-295	469	1	300(1	CARDINAL
admet-295	469	2	2002	DATE
admet-295	469	3	64	CARDINAL
admet-295	470	1	56	CARDINAL
admet-295	470	2	p. o. girodet	PERSON
admet-295	470	3	h. verdoux	PERSON
admet-295	470	4	m. molimard	PERSON
admet-295	470	5	w. haverkamp	PERSON
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admet-295	470	7	n. moore	PERSON
admet-295	471	1	28(1	CARDINAL
admet-295	471	2	2005	DATE
admet-295	471	3	35	CARDINAL
admet-295	472	1	57	CARDINAL
admet-295	472	2	z. laksman	PERSON
admet-295	472	3	b. momciu	PERSON
admet-295	472	4	w. seong	PERSON
admet-295	472	5	s. conacher	PERSON
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admet-295	472	8	l. j. gula	PERSON
admet-295	472	9	a. c. skanes	PERSON
admet-295	472	10	r. yee	PERSON
admet-295	472	11	g. j. klein	PERSON
admet-295	472	12	a. d. krahn	PERSON
admet-295	474	1	j. cardiol	PERSON
admet-295	475	1	115(7	CARDINAL
admet-295	475	2	2015	CARDINAL
admet-295	475	3	907	CARDINAL
admet-295	476	1	rashmi shah admet &	ORG
admet-295	476	2	4(3	CARDINAL
admet-295	476	3	2016	CARDINAL
admet-295	476	4	212	CARDINAL
admet-295	477	1	58	CARDINAL
admet-295	477	2	d. m. roden	PERSON
admet-295	478	1	j. physiol	PERSON
admet-295	479	1	594(9	CARDINAL
admet-295	479	2	2016	CARDINAL
admet-295	479	3	2459	CARDINAL
admet-295	480	1	59	CARDINAL
admet-295	482	1	european medicines agency	ORG
admet-295	482	2	london	GPE
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admet-295	483	1	5	CARDINAL
admet-295	483	2	april 2012	DATE
admet-295	484	1	60	CARDINAL
admet-295	486	1	geneva	GPE
admet-295	486	2	may 2005	DATE
admet-295	487	1	http://www.ich.org/fileadmin/public_web_site/ich_products/guidelines/safety/s7b/step4/s7b_gu	ORG
admet-295	487	2	5	CARDINAL
admet-295	488	1	61	CARDINAL
admet-295	490	1	geneva	GPE
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admet-295	491	1	5	CARDINAL
admet-295	492	1	62	CARDINAL
admet-295	495	1	r3	ORG
admet-295	496	1	international council for harmonisation	ORG
admet-295	496	2	geneva	GPE
admet-295	496	3	december 2015	DATE
admet-295	497	1	http://www.ich.org/fileadmin/public_web_site/ich_products/guidelines/efficacy/e14/e14_q_as_r 3__step4.pdf	CARDINAL
admet-295	497	2	5	CARDINAL
admet-295	498	1	63	CARDINAL
admet-295	498	2	r. r. shah	PERSON
admet-295	500	1	j. clin	PERSON
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admet-295	502	2	188	CARDINAL
admet-295	503	1	64	CARDINAL
admet-295	503	2	y. l. lin	PERSON
admet-295	503	3	m. f. kung	PERSON
admet-295	504	1	2009	DATE
admet-295	504	2	235	CARDINAL
admet-295	505	1	65	CARDINAL
admet-295	505	2	e. i. heath	PERSON
admet-295	505	3	j. infante	PERSON
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admet-295	505	5	t. luu	PERSON
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admet-295	505	8	s. kasubhai	PERSON
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admet-295	505	11	j. f. kleha	PERSON
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admet-295	505	13	m. m. dar	PERSON
admet-295	507	1	71(3	CARDINAL
admet-295	507	2	2013	DATE
admet-295	507	3	565	CARDINAL
admet-295	508	1	66	CARDINAL
admet-295	508	2	k. s. kloth	PERSON
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admet-295	508	10	a. zambelli	PERSON
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admet-295	510	1	j. cancer	PERSON
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admet-295	510	4	1011-1016	CARDINAL
admet-295	511	1	67	CARDINAL
admet-295	511	2	z. lu	PERSON
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admet-295	511	8	r. z. lin	PERSON
admet-295	512	1	sci. transl.	ORG
admet-295	514	1	4(131	CARDINAL
admet-295	514	2	2012)	DATE
admet-295	516	1	68	CARDINAL
admet-295	516	2	l. m. ballou	PERSON
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admet-295	519	3	127	CARDINAL
admet-295	520	1	69	CARDINAL
admet-295	520	2	j. s. lowe	PERSON
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admet-295	523	1	95(3	CARDINAL
admet-295	523	2	2012) 300307	DATE
admet-295	524	1	70	CARDINAL
admet-295	524	2	d. h. staniforth	PERSON
admet-295	526	1	j. clin	PERSON
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admet-295	528	2	615	CARDINAL
admet-295	529	1	71	CARDINAL
admet-295	529	2	d. h. staniforth	PERSON
admet-295	531	1	j. clin	PERSON
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admet-295	533	2	862	CARDINAL
admet-295	534	1	72	CARDINAL
admet-295	534	2	m. malik	PERSON
admet-295	535	1	clin	PERSON
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admet-295	537	2	2002	DATE
admet-295	537	3	209	CARDINAL
admet-295	538	1	73	CARDINAL
admet-295	538	2	m. desai	PERSON
admet-295	538	3	l. li	PERSON
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admet-295	538	6	d. flockhart	PERSON
admet-295	540	1	j. clin	PERSON
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admet-295	543	1	2003	DATE
admet-295	543	2	511	CARDINAL
admet-295	544	1	74	CARDINAL
admet-295	545	1	4.0	CARDINAL
admet-295	545	2	may 28, 2009	DATE
admet-295	545	3	june 14, 2010	DATE
admet-295	546	1	2	CARDINAL
admet-295	547	1	75	CARDINAL
admet-295	547	2	m. schmidinger	PERSON
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admet-295	547	4	m. vogl	PERSON
admet-295	547	5	a. bojic	PERSON
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admet-295	548	1	j. clin	PERSON
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admet-295	551	1	76	CARDINAL
admet-295	551	2	p. s. hall	PERSON
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admet-295	553	2	2013	DATE
admet-295	553	3	72	CARDINAL
admet-295	554	1	77	CARDINAL
admet-295	554	2	s. moustafa	PERSON
admet-295	554	3	t. h. ho	PERSON
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admet-295	556	2	2016	CARDINAL
admet-295	556	3	221	CARDINAL
admet-295	557	1	c. cheng	PERSON
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admet-295	561	3	114	CARDINAL
admet-295	562	1	79	CARDINAL
admet-295	562	2	k. l. kolaja	PERSON
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admet-295	565	1	2011	DATE
admet-295	565	2	111	CARDINAL
admet-295	566	1	http://www.fda.gov/ohrms/dockets/ac/03/briefing/pubs/cpmp.pdf http://www.ich.org/fileadmin/public_web_site/ich_products/guidelines/safety/s7b/step4/s7b_guideline.pdf http://www.ich.org/fileadmin/public_web_site/ich_products/guidelines/safety/s7b/step4/s7b_guideline.pdf http://www.ich.org/fileadmin/public_web_site/ich_products/guidelines/efficacy/e14/e14_guideline.pdf	ORG
admet-295	566	2	4(3	CARDINAL
admet-295	566	3	2016	CARDINAL
admet-295	566	4	212	CARDINAL
admet-295	566	5	10.5599	CARDINAL
admet-295	566	6	229	CARDINAL
admet-295	567	1	80	CARDINAL
admet-295	567	2	m. svoboda	PERSON
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admet-295	567	5	i. kiss	PERSON
admet-295	567	6	r. vyzula	PERSON
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admet-295	570	1	2012	DATE
admet-295	570	2	191	CARDINAL
admet-295	571	1	81	CARDINAL
admet-295	571	2	f. jacob	PERSON
admet-295	571	3	a. y. yonis	PERSON
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admet-295	573	2	2016	CARDINAL
admet-295	574	1	82	CARDINAL
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admet-295	577	1	83	CARDINAL
admet-295	578	1	crizotinib	PERSON
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admet-295	578	3	april 2016	DATE
admet-295	579	1	food and drug administration	ORG
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admet-295	579	3	md 20993	GPE
admet-295	579	4	usa.	GPE
admet-295	579	5	22	CARDINAL
admet-295	580	1	84	CARDINAL
admet-295	580	2	o. abdel-rahman	PERSON
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admet-295	582	1	rev	PERSON
admet-295	582	2	oncol	TIME
admet-295	583	1	2014) 194–207	DATE
admet-295	584	1	85	CARDINAL
admet-295	584	2	b. yang	PERSON
admet-295	584	3	t. papoian	PERSON
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admet-295	587	2	2012	DATE
admet-295	587	3	945	CARDINAL
admet-295	588	1	86	CARDINAL
admet-295	590	1	food and drug administration	ORG
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admet-295	590	3	md 20993	GPE
admet-295	590	4	usa.	GPE
admet-295	590	5	22	CARDINAL
admet-295	591	1	87	CARDINAL
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admet-295	593	3	md 20993	GPE
admet-295	593	4	usa.	GPE
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admet-295	594	1	88	CARDINAL
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admet-295	596	4	usa.	GPE
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admet-295	597	1	89	CARDINAL
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admet-295	599	3	md 20993	GPE
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admet-295	600	1	90	CARDINAL
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admet-295	602	3	md 20993	GPE
admet-295	602	4	usa.	GPE
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admet-295	603	1	91	CARDINAL
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admet-295	608	3	51-60	CARDINAL
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admet-295	612	1	10(3	CARDINAL
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admet-295	614	3	124	CARDINAL
admet-295	615	1	94	CARDINAL
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admet-295	618	1	95	CARDINAL
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admet-295	620	4	usa.	GPE
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admet-295	621	1	96	CARDINAL
admet-295	622	1	fda	ORG
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admet-295	624	4	2016	CARDINAL
admet-295	624	5	212	CARDINAL
admet-295	624	6	md 20993	GPE
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admet-295	624	8	22	CARDINAL
admet-295	625	1	97	CARDINAL
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admet-295	627	4	usa.	GPE
admet-295	627	5	22	CARDINAL
admet-295	628	1	98	CARDINAL
admet-295	629	1	ponatinib	PERSON
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admet-295	630	1	food and drug administration	ORG
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admet-295	630	4	usa.	GPE
admet-295	630	5	22	CARDINAL
admet-295	631	1	99	CARDINAL
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admet-295	634	3	919	CARDINAL
admet-295	635	1	100	CARDINAL
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admet-295	639	1	101	CARDINAL
admet-295	639	2	s. hong	PERSON
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admet-295	642	1	7 (2014) 1851-1867	DATE
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admet-295	643	2	x. yang	PERSON
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admet-295	647	2	1047-1056	CARDINAL
admet-295	648	1	103	CARDINAL
admet-295	648	2	g. w. jean	PERSON
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admet-295	650	3	529-534	CARDINAL
admet-295	651	1	104	CARDINAL
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admet-295	657	2	636	CARDINAL
admet-295	658	1	106	CARDINAL
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admet-295	661	2	3012-3019	CARDINAL
admet-295	662	1	107	CARDINAL
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admet-295	667	1	108	CARDINAL
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admet-295	671	1	109	CARDINAL
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admet-295	683	3	45	CARDINAL
admet-295	684	1	112	CARDINAL
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admet-295	686	1	rev	PERSON
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admet-295	687	2	2012) 13931478	DATE
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admet-295	688	2	j. j. babcock	PERSON
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admet-295	689	2	329	CARDINAL
admet-295	690	1	114	CARDINAL
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admet-295	693	2	2002	DATE
admet-295	693	3	18528-18534	DATE
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admet-295	696	3	66	CARDINAL
admet-295	697	1	116	CARDINAL
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admet-295	699	3	365	CARDINAL
admet-295	700	1	117	CARDINAL
admet-295	700	2	a. arcangeli	PERSON
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admet-295	702	1	2015	CARDINAL
admet-295	703	1	118	CARDINAL
admet-295	703	2	e. lastraioli	PERSON
admet-295	703	3	t. lottini	PERSON
admet-295	703	4	l. bencini	PERSON
admet-295	703	5	m. bernini	PERSON
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admet-295	706	1	2015	CARDINAL
admet-295	706	2	2015) 896432	DATE
admet-295	707	1	119	CARDINAL
admet-295	707	2	a. managò	PERSON
admet-295	707	3	m. zoratti	PERSON
admet-295	707	4	e. gulbins	PERSON
admet-295	707	5	i. szabo	PERSON
admet-295	708	1	biophys acta	PERSON
admet-295	709	1	1863	DATE
admet-295	709	2	2016	CARDINAL
admet-295	709	3	1385-1397	CARDINAL
admet-295	710	1	120	CARDINAL
admet-295	710	2	r. rao	PERSON
admet-295	710	3	m. perez-neut	PERSON
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admet-295	710	5	s. gentile	PERSON
admet-295	711	1	7(2	CARDINAL
admet-295	711	2	2015	CARDINAL
admet-295	711	3	849	CARDINAL
admet-295	712	1	121	CARDINAL
admet-295	712	2	j. garcia-quiroz	PERSON
admet-295	712	3	j. camacho	PERSON
admet-295	714	1	11(3	CARDINAL
admet-295	714	2	2011	DATE
admet-295	715	1	307–314	CARDINAL
admet-295	716	1	122	CARDINAL
admet-295	716	2	r. j. andrade	PERSON
admet-295	716	3	m. i. lucena	PERSON
admet-295	716	4	m. c. fernández	PERSON
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admet-295	716	6	k. pachkoria	PERSON
admet-295	716	7	e. garcía-ruiz	PERSON
admet-295	716	8	b. garcía-muñoz	PERSON
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admet-295	716	11	j. a. durán	PERSON
admet-295	716	12	m. jiménez	PERSON
admet-295	716	13	l. rodrigo	PERSON
admet-295	716	14	m. romero-gomez	PERSON
admet-295	716	15	j. m. navarro	PERSON
admet-295	716	16	r. planas	PERSON
admet-295	716	17	j. costa	PERSON
admet-295	716	18	a. borras	PERSON
admet-295	716	19	a. soler	PERSON
admet-295	716	20	j. salmerón	PERSON
admet-295	716	21	r. martin-vivaldi	PERSON
admet-295	716	22	spanish	NORP
admet-295	717	1	129(2	CARDINAL
admet-295	717	2	2005	DATE
admet-295	717	3	512	CARDINAL
admet-295	718	1	123	CARDINAL
admet-295	718	2	e. björnsson	PERSON
admet-295	718	3	r. olsson	PERSON
admet-295	718	4	42(2	CARDINAL
admet-295	718	5	2005	DATE
admet-295	718	6	481	CARDINAL
admet-295	719	1	4(3	CARDINAL
admet-295	719	2	2016	CARDINAL
admet-295	719	3	212	CARDINAL
admet-295	719	4	10.5599	CARDINAL
admet-295	719	5	231	CARDINAL
admet-295	719	6	124	CARDINAL
admet-295	720	1	july 2009	DATE
admet-295	721	1	food and drug administration	ORG
admet-295	721	2	silver spring	GPE
admet-295	721	3	md	GPE
admet-295	721	4	20993-0002	DATE
admet-295	721	5	usa.	GPE
admet-295	721	6	1	CARDINAL
admet-295	722	1	125	CARDINAL
admet-295	722	2	t. h. brümmendorf	PERSON
admet-295	722	3	j. e. cortes	PERSON
admet-295	722	4	c. a. de souza	PERSON
admet-295	722	5	f. guilhot	PERSON
admet-295	722	6	l. duvillié	PERSON
admet-295	722	7	d. pavlov	PERSON
admet-295	722	8	k. gogat	PERSON
admet-295	722	9	a. m. countouriotis	PERSON
admet-295	722	10	c. gambacorti-passerini	PERSON
admet-295	724	1	j. haematol	PERSON
admet-295	725	1	168(1	CARDINAL
admet-295	725	2	2015	CARDINAL
admet-295	725	3	69-81	CARDINAL
admet-295	726	1	2016	DATE
admet-295	726	2	iapc	ORG
admet-295	726	3	zagreb	GPE
admet-295	726	4	croatia	GPE
admet-295	727	1	http://creativecommons.org/licenses/by/3.0/	ORG
admet-295	727	2	http://creativecommons.org/licenses/by/3.0/	ORG