id	sid	eid	entity	type
admet-733	1	1	10.5599	CARDINAL
admet-733	1	2	222	CARDINAL
admet-733	1	3	7(4	CARDINAL
admet-733	1	4	2019	CARDINAL
admet-733	1	5	222	CARDINAL
admet-733	1	6	issn	PERSON
admet-733	1	7	1848-7718	DATE
admet-733	1	8	discovery geoffrey holdgate*1	PERSON
admet-733	1	9	kevin embrey2	PERSON
admet-733	1	10	alexander milbradt2	PERSON
admet-733	1	11	gareth davies1 1	PERSON
admet-733	1	12	alderley park	FAC
admet-733	1	13	2	CARDINAL
admet-733	1	14	astrazeneca	GPE
admet-733	1	15	cambridge	GPE
admet-733	1	16	uk	GPE
admet-733	2	1	+44	CARDINAL
admet-733	2	2	234218	DATE
admet-733	2	3	september 30, 2019	DATE
admet-733	2	4	november 19, 2019	DATE
admet-733	2	5	december 11, 2019	DATE
admet-733	6	1	first	ORDINAL
admet-733	6	2	the early 1990s	DATE
admet-733	7	1	first	ORDINAL
admet-733	7	2	itc	ORG
admet-733	8	1	1	CARDINAL
admet-733	8	2	first	ORDINAL
admet-733	8	3	2	CARDINAL
admet-733	9	1	first	ORDINAL
admet-733	9	2	3	CARDINAL
admet-733	9	3	4	CARDINAL
admet-733	10	1	a few hundred	CARDINAL
admet-733	10	2	each week	DATE
admet-733	10	3	the late 1980s	DATE
admet-733	10	4	hts	GPE
admet-733	10	5	almost half	CARDINAL
admet-733	10	6	the mid-1990s	DATE
admet-733	10	7	5,6	CARDINAL
admet-733	12	1	http://dx.doi.org/10.5599/admet.733 http://www.pub.iapchem.org/ojs/index.php/admet/index admet & dmpk 7(4	ORG
admet-733	12	2	2019	CARDINAL
admet-733	12	3	222	CARDINAL
admet-733	12	4	10.5599	CARDINAL
admet-733	12	5	223	CARDINAL
admet-733	12	6	8	CARDINAL
admet-733	12	7	thousands	CARDINAL
admet-733	12	8	9	CARDINAL
admet-733	14	1	10	CARDINAL
admet-733	15	1	11	CARDINAL
admet-733	16	1	12,13	CARDINAL
admet-733	17	1	today	DATE
admet-733	34	1	1	CARDINAL
admet-733	34	2	al. admet	ORG
admet-733	34	3	7(4	CARDINAL
admet-733	34	4	2019	CARDINAL
admet-733	34	5	222	CARDINAL
admet-733	34	6	241 224	CARDINAL
admet-733	36	1	1	CARDINAL
admet-733	37	1	1	CARDINAL
admet-733	37	2	2	CARDINAL
admet-733	37	3	purity sds-page	PERSON
admet-733	37	4	± 20 %	PERCENT
admet-733	37	5	3	CARDINAL
admet-733	37	6	280	CARDINAL
admet-733	37	7	205	CARDINAL
admet-733	37	8	340	CARDINAL
admet-733	37	9	ε bradford	ORG
admet-733	37	10	bsa	ORG
admet-733	37	11	4	CARDINAL
admet-733	37	12	itc	ORG
admet-733	38	1	15 %	PERCENT
admet-733	38	2	2-fold	CARDINAL
admet-733	38	3	1 kcal	QUANTITY
admet-733	38	4	dba	ORG
admet-733	38	5	2-fold	CARDINAL
admet-733	38	6	±15 %	PERCENT
admet-733	38	7	two	CARDINAL
admet-733	38	8	bradford & a280	ORG
admet-733	38	9	tdc	GPE
admet-733	38	10	10 6	CARDINAL
admet-733	38	11	s -1 m -1	ORG
admet-733	38	12	ki	PERSON
admet-733	38	13	ki	PERSON
admet-733	38	14	5	CARDINAL
admet-733	38	15	selwyn	ORG
admet-733	38	16	ptm	ORG
admet-733	38	17	bsa	ORG
admet-733	38	18	michaelis constant	PERSON
admet-733	38	19	dba	ORG
admet-733	38	20	tdc	GPE
admet-733	40	1	7(4	CARDINAL
admet-733	40	2	2019	CARDINAL
admet-733	40	3	222	CARDINAL
admet-733	40	4	10.5599	CARDINAL
admet-733	40	5	225	CARDINAL
admet-733	44	1	2	CARDINAL
admet-733	44	2	2	CARDINAL
admet-733	46	1	itc	ORG
admet-733	46	2	atad2	ORG
admet-733	46	3	itc	ORG
admet-733	46	4	itc	ORG
admet-733	46	5	mapkapk2	ORG
admet-733	47	1	itc	ORG
admet-733	47	2	atad2	ORG
admet-733	47	3	2	CARDINAL
admet-733	47	4	mapkapk2	ORG
admet-733	47	5	2	CARDINAL
admet-733	51	1	itc	ORG
admet-733	52	1	post hts	ORG
admet-733	56	1	al. admet	ORG
admet-733	56	2	7(4	CARDINAL
admet-733	56	3	2019	CARDINAL
admet-733	56	4	222	CARDINAL
admet-733	56	5	14	CARDINAL
admet-733	58	1	astrazeneca, hts development	ORG
admet-733	58	2	around 1000	CARDINAL
admet-733	58	3	around 7000	CARDINAL
admet-733	58	4	around 2 million	CARDINAL
admet-733	61	1	3	CARDINAL
admet-733	67	1	3	CARDINAL
admet-733	68	1	firstly	ORDINAL
admet-733	68	2	hts	GPE
admet-733	68	3	around $90k	MONEY
admet-733	68	4	secondly	ORDINAL
admet-733	69	1	1	CARDINAL
admet-733	70	1	1 million	CARDINAL
admet-733	74	1	7(4	CARDINAL
admet-733	74	2	2019	CARDINAL
admet-733	74	3	222	CARDINAL
admet-733	74	4	10.5599	CARDINAL
admet-733	74	5	227	CARDINAL
admet-733	74	6	3	CARDINAL
admet-733	75	1	keap1	ORG
admet-733	75	2	180	CARDINAL
admet-733	76	1	60	CARDINAL
admet-733	76	2	17%	PERCENT
admet-733	77	1	38%	PERCENT
admet-733	78	1	27%	PERCENT
admet-733	78	2	38% to 5%	PERCENT
admet-733	78	3	180	CARDINAL
admet-733	79	1	90%	PERCENT
admet-733	79	2	ttbk1	DATE
admet-733	79	3	250	CARDINAL
admet-733	79	4	69	CARDINAL
admet-733	79	5	adp-glo	ORG
admet-733	79	6	630	CARDINAL
admet-733	79	7	itc	ORG
admet-733	79	8	50	CARDINAL
admet-733	79	9	one	CARDINAL
admet-733	79	10	77%	PERCENT
admet-733	80	1	90%	PERCENT
admet-733	80	2	40%	PERCENT
admet-733	80	3	1	CARDINAL
admet-733	80	4	2	CARDINAL
admet-733	80	5	3	CARDINAL
admet-733	80	6	250	CARDINAL
admet-733	80	7	1	CARDINAL
admet-733	80	8	90 2	CARDINAL
admet-733	80	9	50 3	CARDINAL
admet-733	80	10	10 4	CARDINAL
admet-733	80	11	100 190	CARDINAL
admet-733	80	12	90	CARDINAL
admet-733	80	13	4	CARDINAL
admet-733	80	14	1	CARDINAL
admet-733	80	15	16 3	DATE
admet-733	80	16	13	CARDINAL
admet-733	80	17	hts	GPE
admet-733	81	1	keap1	GPE
admet-733	81	2	ech	ORG
admet-733	81	3	1	CARDINAL
admet-733	81	4	1	CARDINAL
admet-733	81	5	ttbk1	PERSON
admet-733	81	6	1	CARDINAL
admet-733	81	7	apc	ORG
admet-733	81	8	two	CARDINAL
admet-733	82	1	15	CARDINAL
admet-733	83	1	16	CARDINAL
admet-733	87	1	17	CARDINAL
admet-733	88	1	first	ORDINAL
admet-733	88	2	al. admet	ORG
admet-733	88	3	7(4	CARDINAL
admet-733	88	4	2019	CARDINAL
admet-733	88	5	222	CARDINAL
admet-733	88	6	4	CARDINAL
admet-733	90	1	18	CARDINAL
admet-733	90	2	19	CARDINAL
admet-733	91	1	1	CARDINAL
admet-733	93	1	many years	DATE
admet-733	98	1	the late 1990s	DATE
admet-733	98	2	20	CARDINAL
admet-733	98	3	21	CARDINAL
admet-733	104	1	2	CARDINAL
admet-733	105	1	22	CARDINAL
admet-733	105	2	7(4	CARDINAL
admet-733	105	3	2019	CARDINAL
admet-733	105	4	222	CARDINAL
admet-733	105	5	10.5599	CARDINAL
admet-733	105	6	229 100	CARDINAL
admet-733	105	7	almost 3000	CARDINAL
admet-733	111	1	2	CARDINAL
admet-733	116	1	several years	DATE
admet-733	116	2	23	CARDINAL
admet-733	117	1	50 %	PERCENT
admet-733	122	1	al. admet	ORG
admet-733	122	2	7(4	CARDINAL
admet-733	122	3	2019	CARDINAL
admet-733	122	4	222	CARDINAL
admet-733	123	1	3(a	CARDINAL
admet-733	125	1	200 300 400	TIME
admet-733	125	2		CARDINAL
admet-733	125	3	3	CARDINAL
admet-733	128	1	5 °	QUANTITY
admet-733	129	1	first	ORDINAL
admet-733	134	1	500,000	CARDINAL
admet-733	134	2	around 0.5 g	QUANTITY
admet-733	134	3	40 kda	QUANTITY
admet-733	136	1	24	CARDINAL
admet-733	136	2	mm	PERSON
admet-733	137	1	2	CARDINAL
admet-733	137	2	first	ORDINAL
admet-733	137	3	3	CARDINAL
admet-733	138	1	screener®	ORG
admet-733	138	2	genedata	ORG
admet-733	138	3	basel	GPE
admet-733	138	4	switzerland	GPE
admet-733	139	1	discovery	PRODUCT
admet-733	139	2	2	CARDINAL
admet-733	139	3	around 35	CARDINAL
admet-733	139	4	25	CARDINAL
admet-733	141	1	25	CARDINAL
admet-733	143	1	26	CARDINAL
admet-733	144	1	7(4	CARDINAL
admet-733	144	2	2019	CARDINAL
admet-733	144	3	222	CARDINAL
admet-733	144	4	10.5599	CARDINAL
admet-733	144	5	231	CARDINAL
admet-733	146	1	1 million	CARDINAL
admet-733	146	2	1030	CARDINAL
admet-733	146	3	36	CARDINAL
admet-733	146	4	1019-fold	CARDINAL
admet-733	146	5	1000	CARDINAL
admet-733	146	6	108	CARDINAL
admet-733	146	7	12	CARDINAL
admet-733	148	1	hann	GPE
admet-733	149	1	27	CARDINAL
admet-733	154	1	two	CARDINAL
admet-733	164	1	50 kda	QUANTITY
admet-733	164	2	15n	CARDINAL
admet-733	166	1	28	CARDINAL
admet-733	168	1	10 50 μm	CARDINAL
admet-733	169	1	itc	ORG
admet-733	170	1	al. admet	ORG
admet-733	170	2	7(4	CARDINAL
admet-733	170	3	2019	CARDINAL
admet-733	170	4	222	CARDINAL
admet-733	171	1	29	CARDINAL
admet-733	173	1	llc	GPE
admet-733	174	1	30	CARDINAL
admet-733	177	1	31	CARDINAL
admet-733	179	1	32	CARDINAL
admet-733	180	1	microscale thermophoresis	PERSON
admet-733	181	1	33	CARDINAL
admet-733	182	1	34	CARDINAL
admet-733	185	1	one	CARDINAL
admet-733	188	1	around 14000	CARDINAL
admet-733	189	1	3456	CARDINAL
admet-733	190	1	3072	CARDINAL
admet-733	190	2	1152	CARDINAL
admet-733	191	1	768	CARDINAL
admet-733	192	1	less than 20	CARDINAL
admet-733	192	2	less than 275	CARDINAL
admet-733	192	3	less than 3	CARDINAL
admet-733	192	4	greater than 100	CARDINAL
admet-733	194	1	35	CARDINAL
admet-733	195	1	768	CARDINAL
admet-733	195	2	4	CARDINAL
admet-733	196	1	spr. admet	ORG
admet-733	196	2	7(4	CARDINAL
admet-733	196	3	2019	CARDINAL
admet-733	196	4	222	CARDINAL
admet-733	196	5	10.5599	CARDINAL
admet-733	196	6	233	CARDINAL
admet-733	196	7	4	CARDINAL
admet-733	197	1	5	CARDINAL
admet-733	199	1	about 50 %	PERCENT
admet-733	199	2	ec50	WORK_OF_ART
admet-733	204	1	itc	ORG
admet-733	205	1	5	CARDINAL
admet-733	207	1	al. admet & dmpk 7(4	ORG
admet-733	207	2	2019	CARDINAL
admet-733	207	3	222	CARDINAL
admet-733	207	4	4	CARDINAL
admet-733	209	1	one	CARDINAL
admet-733	214	1	hts	GPE
admet-733	215	1	hts	GPE
admet-733	217	1	36	CARDINAL
admet-733	218	1	4	CARDINAL
admet-733	219	1	15	CARDINAL
admet-733	219	2	2d	DATE
admet-733	219	3	itc	ORG
admet-733	219	4	one	CARDINAL
admet-733	219	5	medium mm pm medium	PERSON
admet-733	222	1	equilibrates	NORP
admet-733	225	1	one	CARDINAL
admet-733	227	1	itc	ORG
admet-733	227	2	one	CARDINAL
admet-733	227	3	second	ORDINAL
admet-733	228	1	7(4	CARDINAL
admet-733	228	2	2019	CARDINAL
admet-733	228	3	222	CARDINAL
admet-733	228	4	10.5599	CARDINAL
admet-733	228	5	235	CARDINAL
admet-733	228	6	itc	ORG
admet-733	228	7	van’t hoff	PERSON
admet-733	230	1	fgfr1	ORG
admet-733	230	2	37	CARDINAL
admet-733	233	1	38	CARDINAL
admet-733	236	1	1	CARDINAL
admet-733	236	2	3	CARDINAL
admet-733	236	3	3	CARDINAL
admet-733	236	4	3phosphohydroxypyruvate	CARDINAL
admet-733	237	1	3	CARDINAL
admet-733	237	2	3phosphohydroxypyruvate	CARDINAL
admet-733	237	3	first	ORDINAL
admet-733	239	1	39	CARDINAL
admet-733	241	1	384	CARDINAL
admet-733	241	2	4	CARDINAL
admet-733	241	3	34	CARDINAL
admet-733	242	1	2d	DATE
admet-733	242	2	6a	CARDINAL
admet-733	243	1	6b	CARDINAL
admet-733	243	2	1	CARDINAL
admet-733	243	3	1	CARDINAL
admet-733	243	4	5	CARDINAL
admet-733	243	5	2	CARDINAL
admet-733	243	6	1.95	CARDINAL
admet-733	243	7	6b	CARDINAL
admet-733	244	1	5-fluoro	QUANTITY
admet-733	245	1	2	CARDINAL
admet-733	246	1	2	CARDINAL
admet-733	247	1	4	CARDINAL
admet-733	248	1	4	CARDINAL
admet-733	248	2	6c	CARDINAL
admet-733	248	3	5	CARDINAL
admet-733	248	4	10-fold	CARDINAL
admet-733	249	1	al. admet	ORG
admet-733	249	2	7(4	CARDINAL
admet-733	249	3	2019	CARDINAL
admet-733	249	4	222	CARDINAL
admet-733	249	5	6	CARDINAL
admet-733	249	6	2	CARDINAL
admet-733	249	7	980 ± 60	MONEY
admet-733	249	8	2	CARDINAL
admet-733	249	9	1.95	CARDINAL
admet-733	249	10	4	CARDINAL
admet-733	249	11	5	CARDINAL
admet-733	250	1	2d	CARDINAL
admet-733	251	1	itc	ORG
admet-733	251	2	spr	ORG
admet-733	251	3	7a	CARDINAL
admet-733	251	4	approximately 20-fold	CARDINAL
admet-733	252	1	1d	CARDINAL
admet-733	255	1	mm	PERSON
admet-733	256	1	first	ORDINAL
admet-733	257	1	1	CARDINAL
admet-733	257	2	1	CARDINAL
admet-733	257	3	2	CARDINAL
admet-733	257	4	5	CARDINAL
admet-733	258	1	7(4	CARDINAL
admet-733	258	2	2019	CARDINAL
admet-733	258	3	222	CARDINAL
admet-733	258	4	10.5599	CARDINAL
admet-733	258	5	237	CARDINAL
admet-733	258	6	7	CARDINAL
admet-733	258	7	0.33 ± 0.08 µm	MONEY
admet-733	258	8	0.78 ± 0.01	MONEY
admet-733	259	1	0.4 ± 0.03	MONEY
admet-733	260	1	6.7 ± 0.5 µm	MONEY
admet-733	261	1	2	CARDINAL
admet-733	261	2	40	CARDINAL
admet-733	261	3	around 109–1011	CARDINAL
admet-733	265	1	enoyl reductase inha	ORG
admet-733	265	2	11	CARDINAL
admet-733	265	3	more than 65 billion	MONEY
admet-733	266	1	four	CARDINAL
admet-733	268	1	2 mm nad+	QUANTITY
admet-733	268	2	100 μm	CARDINAL
admet-733	270	1	5	CARDINAL
admet-733	273	1	7	CARDINAL
admet-733	273	2	8	CARDINAL
admet-733	273	3	al. admet	ORG
admet-733	273	4	7(4	CARDINAL
admet-733	273	5	2019	CARDINAL
admet-733	273	6	222	CARDINAL
admet-733	274	1	5	CARDINAL
admet-733	275	1	inha.nad + inha.nadh 6	ORG
admet-733	275	2	100	CARDINAL
admet-733	275	3	13.4 ±	QUANTITY
admet-733	275	4	100	CARDINAL
admet-733	275	5	46.7 ± 11.6 0.09 ±	QUANTITY
admet-733	275	6	100	CARDINAL
admet-733	275	7	100	CARDINAL
admet-733	275	8	100	CARDINAL
admet-733	275	9	100	CARDINAL
admet-733	275	10	100	CARDINAL
admet-733	275	11	49.0 ± 2.9 0.06 ± 0.03	QUANTITY
admet-733	275	12	1.2 12	CARDINAL
admet-733	275	13	100	CARDINAL
admet-733	275	14	100	CARDINAL
admet-733	275	15	6.3 ± 2.6	QUANTITY
admet-733	278	1	6	CARDINAL
admet-733	278	2	7	CARDINAL
admet-733	278	3	8	CARDINAL
admet-733	278	4	9	CARDINAL
admet-733	278	5	10	CARDINAL
admet-733	278	6	11	CARDINAL
admet-733	278	7	12	CARDINAL
admet-733	278	8	8	CARDINAL
admet-733	283	1	itc	ORG
admet-733	288	1	discovery	PRODUCT
admet-733	289	1	7(4	CARDINAL
admet-733	289	2	2019	CARDINAL
admet-733	289	3	222	CARDINAL
admet-733	289	4	10.5599	CARDINAL
admet-733	289	5	239	CARDINAL
admet-733	289	6	41	CARDINAL
admet-733	290	1	the last 5 years or so	DATE
admet-733	295	1	1	CARDINAL
admet-733	295	2	t. wiseman	PERSON
admet-733	295	3	s. williston	PERSON
admet-733	295	4	j.f.	GPE
admet-733	295	5	brandts	GPE
admet-733	295	6	l.n. lin.	PERSON
admet-733	298	1	179	CARDINAL
admet-733	298	2	1989	DATE
admet-733	298	3	131	CARDINAL
admet-733	299	1	2	CARDINAL
admet-733	299	2	a. frostell	PERSON
admet-733	299	3	r. karlsson	PERSON
admet-733	299	4	m. kullman	PERSON
admet-733	299	5	a. larsson	PERSON
admet-733	299	6	m. malmqvist	PERSON
admet-733	302	1	j. mol.	PERSON
admet-733	303	1	3 (1990	CARDINAL
admet-733	303	2	208	CARDINAL
admet-733	304	1	3	CARDINAL
admet-733	304	2	j.m. kerr	PERSON
admet-733	304	3	m.a. siani	PERSON
admet-733	304	4	s.c. banville	GPE
admet-733	304	5	d.v.	GPE
admet-733	307	1	acad	ORG
admet-733	308	1	sci. u.s.a. 89 (	ORG
admet-733	308	2	1992	DATE
admet-733	308	3	4505-4509	DATE
admet-733	309	1	4	CARDINAL
admet-733	309	2	s.b.	GPE
admet-733	309	3	shuker	ORG
admet-733	309	4	p.j.	GPE
admet-733	309	5	hajduk	ORG
admet-733	309	6	r.p.	GPE
admet-733	309	7	fesik	PERSON
admet-733	311	1	274	CARDINAL
admet-733	311	2	1996	DATE
admet-733	311	3	1531-1534	CARDINAL
admet-733	312	1	5	CARDINAL
admet-733	312	2	burch	GPE
admet-733	312	3	d.j. kyle	PERSON
admet-733	315	1	8 (1991	DATE
admet-733	315	2	141	CARDINAL
admet-733	316	1	6	CARDINAL
admet-733	316	2	pereira	GPE
admet-733	316	3	j.a. williams.	PERSON
admet-733	318	1	j. pharmacol	PERSON
admet-733	319	1	152	CARDINAL
admet-733	319	2	2007	DATE
admet-733	319	3	53-61	CARDINAL
admet-733	320	1	7	CARDINAL
admet-733	320	2	miller	ORG
admet-733	320	3	m.m. melnick	PERSON
admet-733	320	4	m. lall	PERSON
admet-733	320	5	c. donovan	PERSON
admet-733	320	6	r.w. sarver	GPE
admet-733	320	7	d.y. lee	PERSON
admet-733	320	8	j. ohren	PERSON
admet-733	320	9	d. emerson	ORG
admet-733	325	1	75 (2010	DATE
admet-733	325	2	444	CARDINAL
admet-733	326	1	8	CARDINAL
admet-733	326	2	pfaff	ORG
admet-733	326	3	m.s. chimenti, m.j. kelly	ORG
admet-733	326	4	m.r. arkin	PERSON
admet-733	330	1	1278	CARDINAL
admet-733	330	2	2015	CARDINAL
admet-733	330	3	587	CARDINAL
admet-733	331	1	9	CARDINAL
admet-733	331	2	o'connell	PERSON
admet-733	331	3	j. ramsay	PERSON
admet-733	331	4	s.f.	GPE
admet-733	331	5	rieth	ORG
admet-733	331	6	m.j. shapiro	PERSON
admet-733	331	7	j.g. stroh.	PERSON
admet-733	333	1	86	CARDINAL
admet-733	334	1	10	CARDINAL
admet-733	334	2	discovery	PRODUCT
admet-733	336	1	neurosci	PERSON
admet-733	337	1	9 (	PERCENT
admet-733	337	2	2018	DATE
admet-733	337	3	29	CARDINAL
admet-733	338	1	11	CARDINAL
admet-733	338	2	g. klebe	PERSON
admet-733	340	1	nat	PERSON
admet-733	343	1	14 (	PERCENT
admet-733	343	2	95	CARDINAL
admet-733	344	1	12	CARDINAL
admet-733	344	2	m.g. carneiro	PERSON
admet-733	344	3	e. ab	PERSON
admet-733	344	4	s. theisgen	PERSON
admet-733	344	5	g. siegal	PERSON
admet-733	347	1	61	CARDINAL
admet-733	347	2	2017	CARDINAL
admet-733	347	3	485	CARDINAL
admet-733	348	1	al. admet & dmpk 7(4	ORG
admet-733	348	2	2019	CARDINAL
admet-733	348	3	222	CARDINAL
admet-733	348	4	13	CARDINAL
admet-733	348	5	masson	PERSON
admet-733	348	6	m.l. jenkins	PERSON
admet-733	348	7	j.e. burke	PERSON
admet-733	350	1	opin	PERSON
admet-733	352	1	12	CARDINAL
admet-733	352	2	2017	CARDINAL
admet-733	352	3	981	CARDINAL
admet-733	353	1	14	CARDINAL
admet-733	353	2	m. a. walters	PERSON
admet-733	354	1	chemical con	ORG
admet-733	355	1	513	CARDINAL
admet-733	355	2	2014	DATE
admet-733	355	3	481	CARDINAL
admet-733	356	1	15	CARDINAL
admet-733	356	2	m.w. pantoliano	GPE
admet-733	356	3	kwasnoski	PERSON
admet-733	356	4	v.s. lobanov	PERSON
admet-733	356	5	j. myslik	PERSON
admet-733	356	6	e. graf	PERSON
admet-733	356	7	t. carver	GPE
admet-733	356	8	e. asel	PERSON
admet-733	356	9	b.a. springer, p. lane	PERSON
admet-733	358	1	j. biomol	PERSON
admet-733	360	1	6 (2001	DATE
admet-733	360	2	429	CARDINAL
admet-733	361	1	16	CARDINAL
admet-733	361	2	o'connell	PERSON
admet-733	361	3	j. ramsay	PERSON
admet-733	361	4	s.f.	GPE
admet-733	361	5	rieth	ORG
admet-733	361	6	m.j. shapiro	PERSON
admet-733	361	7	j.g. stroh.	PERSON
admet-733	364	1	86	CARDINAL
admet-733	365	1	17	CARDINAL
admet-733	365	2	r.e. hubbard	PERSON
admet-733	368	1	61	CARDINAL
admet-733	368	2	2017	CARDINAL
admet-733	368	3	453	CARDINAL
admet-733	369	1	18	CARDINAL
admet-733	369	2	i. navratilova	PERSON
admet-733	369	3	a.l. hopkins	ORG
admet-733	373	1	1 (2010	DATE
admet-733	373	2	44	CARDINAL
admet-733	374	1	19	CARDINAL
admet-733	374	2	kranz	PERSON
admet-733	374	3	c. schalk-hihi	PERSON
admet-733	378	1	493	CARDINAL
admet-733	378	2	2011	DATE
admet-733	378	3	277	CARDINAL
admet-733	379	1	20	CARDINAL
admet-733	379	2	van breemen	PERSON
admet-733	379	3	c.r	GPE
admet-733	379	4	huang	PERSON
admet-733	379	5	d. nikolic	PERSON
admet-733	379	6	c.p. woodbury	GPE
admet-733	379	7	zhao	PERSON
admet-733	379	8	d.l. venton	PERSON
admet-733	382	1	69	CARDINAL
admet-733	382	2	1997) 21592164	DATE
admet-733	383	1	21	CARDINAL
admet-733	383	2	o'connell	PERSON
admet-733	383	3	j. ramsay	PERSON
admet-733	383	4	s.f.	GPE
admet-733	383	5	rieth	ORG
admet-733	383	6	m.j. shapiro	PERSON
admet-733	383	7	j.g. stroh.	PERSON
admet-733	386	1	86	CARDINAL
admet-733	387	1	22	CARDINAL
admet-733	387	2	i. sinclair	PERSON
admet-733	387	3	m. bachman	PERSON
admet-733	387	4	d. addison	PERSON
admet-733	387	5	m. rohman	PERSON
admet-733	387	6	d.c. murray	PERSON
admet-733	387	7	g. davies	PERSON
admet-733	387	8	e. mouchet	PERSON
admet-733	387	9	m.e. tonge	ORG
admet-733	387	10	r.g. stearns	ORG
admet-733	387	11	l. ghislain	PERSON
admet-733	387	12	s.s. datwani	PERSON
admet-733	387	13	l. majlof	PERSON
admet-733	387	14	e. hall	ORG
admet-733	387	15	jones	PERSON
admet-733	387	16	e. hoyes	PERSON
admet-733	387	17	j. olechno	PERSON
admet-733	387	18	r.n. ellson	GPE
admet-733	387	19	p.e. barran	GPE
admet-733	387	20	s.d. pringle	PERSON
admet-733	387	21	m.r. morris	PERSON
admet-733	387	22	j. wingfield	PERSON
admet-733	390	1	91	CARDINAL
admet-733	390	2	3790-3794	DATE
admet-733	391	1	23	CARDINAL
admet-733	391	2	b. bordeau	PERSON
admet-733	391	3	m.d. cummings	PERSON
admet-733	391	4	m.j. pucci	PERSON
admet-733	391	5	l.e.	GPE
admet-733	391	6	zawadzke	GPE
admet-733	391	7	b.a.	GPE
admet-733	391	8	dougherty	GPE
admet-733	391	9	j.a.	GPE
admet-733	391	10	tredup	GPE
admet-733	391	11	j.w. bryson	PERSON
admet-733	391	12	j. yanchunas	GPE
admet-733	391	13	m.l. doyle	GPE
admet-733	391	14	m.r. witmer	PERSON
admet-733	391	15	m.i	PERSON
admet-733	391	16	r.l. desjarlais	PERSON
admet-733	391	17	e.p. jaeger	GPE
admet-733	391	18	h. devine	PERSON
admet-733	391	19	e.d.	GPE
admet-733	391	20	asel	GPE
admet-733	391	21	b.a. springer	PERSON
admet-733	391	22	r. bone	PERSON
admet-733	391	23	todd	PERSON
admet-733	393	1	j. biol	PERSON
admet-733	395	1	280	CARDINAL
admet-733	395	2	11704-11712	DATE
admet-733	396	1	24	CARDINAL
admet-733	396	2	m. redhead	PERSON
admet-733	396	3	r. satchell	PERSON
admet-733	396	4	c. mccarthy	PERSON
admet-733	396	5	s. pollack	PERSON
admet-733	396	6	j. unitt	PERSON
admet-733	398	1	56	CARDINAL
admet-733	398	2	2017	CARDINAL
admet-733	398	3	6187-6199	DATE
admet-733	399	1	25	CARDINAL
admet-733	399	2	erlanson	ORG
admet-733	399	3	s.w. fesik	PERSON
admet-733	399	4	r.e. hubbard	PERSON
admet-733	399	5	w. jahnke	PERSON
admet-733	399	6	h. jhoti	PERSON
admet-733	400	1	twenty years	DATE
admet-733	400	2	discovery	PRODUCT
admet-733	403	1	15	CARDINAL
admet-733	403	2	2016	CARDINAL
admet-733	403	3	605	CARDINAL
admet-733	404	1	26	CARDINAL
admet-733	404	2	k. amaning	PERSON
admet-733	404	3	m. maschberger	PERSON
admet-733	404	4	f. vallee	PERSON
admet-733	404	5	baaske	GPE
admet-733	404	6	s. duhr	PERSON
admet-733	404	7	d. breitsprecher	GPE
admet-733	404	8	a. rak	PERSON
admet-733	406	1	j. biomol	PERSON
admet-733	408	1	21	CARDINAL
admet-733	408	2	2016	CARDINAL
admet-733	408	3	414	CARDINAL
admet-733	409	1	27	CARDINAL
admet-733	409	2	m.m. hann	PERSON
admet-733	410	1	ten years	DATE
admet-733	411	1	curr	PERSON
admet-733	412	1	opin	GPE
admet-733	415	1	15 (2011	DATE
admet-733	415	2	489	CARDINAL
admet-733	416	1	28	CARDINAL
admet-733	416	2	a.o. frank	PERSON
admet-733	416	3	fesik	PERSON
admet-733	418	1	j. biomol	PERSON
admet-733	419	1	56	CARDINAL
admet-733	419	2	2013	DATE
admet-733	419	3	65	CARDINAL
admet-733	420	1	29] a.m.	TIME
admet-733	421	1	giannetti	PERSON
admet-733	425	1	493	CARDINAL
admet-733	425	2	2011	DATE
admet-733	425	3	169	CARDINAL
admet-733	426	1	30	CARDINAL
admet-733	426	2	d. beckett	PERSON
admet-733	426	3	e. kovaleva	PERSON
admet-733	426	4	p.j. schatz	ORG
admet-733	427	1	biotin holoenzyme	ORG
admet-733	428	1	sci	ORG
admet-733	428	2	8 (1999	DATE
admet-733	428	3	921	CARDINAL
admet-733	429	1	31	CARDINAL
admet-733	429	2	c.a.	GPE
admet-733	429	3	shepherd	GPE
admet-733	429	4	a.l. hopkins	GPE
admet-733	429	5	i. navratilova	PERSON
admet-733	435	1	116	CARDINAL
admet-733	435	2	2014	DATE
admet-733	435	3	113	CARDINAL
admet-733	436	1	admet & dmpk 7(4	ORG
admet-733	436	2	2019	CARDINAL
admet-733	436	3	222	CARDINAL
admet-733	436	4	10.5599	CARDINAL
admet-733	436	5	241	CARDINAL
admet-733	436	6	32	CARDINAL
admet-733	436	7	scott	ORG
admet-733	436	8	m.t.	GPE
admet-733	436	9	t. pukala	GPE
admet-733	436	10	m. marsh	PERSON
admet-733	436	11	blundell	ORG
admet-733	436	12	a.r. venkitaraman	PERSON
admet-733	436	13	c. abell	PERSON
admet-733	436	14	m. hyvönen	PERSON
admet-733	438	1	14 (2013	DATE
admet-733	438	2	332	CARDINAL
admet-733	439	1	33	CARDINAL
admet-733	439	2	m. jerabek-willemsen	PERSON
admet-733	439	3	c.j. wienken	GPE
admet-733	439	4	d. braun	ORG
admet-733	439	5	baaske	GPE
admet-733	439	6	s. duhr	PERSON
admet-733	442	1	technol	ORG
admet-733	442	2	9 (2011	DATE
admet-733	442	3	342	CARDINAL
admet-733	443	1	34	CARDINAL
admet-733	443	2	k. amaning	PERSON
admet-733	443	3	m. maschberger	PERSON
admet-733	443	4	f. vallee	PERSON
admet-733	443	5	baaske	GPE
admet-733	443	6	s. duhr	PERSON
admet-733	443	7	d. breitsprecher	GPE
admet-733	443	8	a. rak	PERSON
admet-733	447	1	21	CARDINAL
admet-733	447	2	2016	CARDINAL
admet-733	447	3	414	CARDINAL
admet-733	448	1	35	CARDINAL
admet-733	448	2	genick	PERSON
admet-733	448	3	d. barlier	PERSON
admet-733	448	4	d. monna	NORP
admet-733	448	5	r. brunner	PERSON
admet-733	448	6	c. bé	PERSON
admet-733	448	7	c. scheufler	GPE
admet-733	448	8	j. ottl	GPE
admet-733	450	1	j. biomol	PERSON
admet-733	452	1	19	CARDINAL
admet-733	452	2	2014	DATE
admet-733	452	3	707	CARDINAL
admet-733	453	1	36	CARDINAL
admet-733	453	2	d. martinez molina	PERSON
admet-733	456	1	pharmacol	PERSON
admet-733	458	1	56	CARDINAL
admet-733	458	2	2016	CARDINAL
admet-733	458	3	141	CARDINAL
admet-733	459	1	37	CARDINAL
admet-733	459	2	t. klein	GPE
admet-733	459	3	n. vajpai	PERSON
admet-733	459	4	j.j. phillips	PERSON
admet-733	459	5	g. davies	PERSON
admet-733	459	6	g.a. holdgate	PERSON
admet-733	459	7	c. phillips	PERSON
admet-733	459	8	j.a. tucker	PERSON
admet-733	459	9	r.a. norman	PERSON
admet-733	459	10	a.d. scott	PERSON
admet-733	459	11	d.r. higazi	PERSON
admet-733	459	12	d. lowe	PERSON
admet-733	459	13	g.s. thompson	PERSON
admet-733	460	1	fgfr1	DATE
admet-733	461	1	nat	PERSON
admet-733	462	1	commun	PERSON
admet-733	463	1	6 (	PERCENT
admet-733	464	1	38	CARDINAL
admet-733	464	2	discovery	PRODUCT
admet-733	466	1	neurosci	PERSON
admet-733	467	1	9 (	PERCENT
admet-733	467	2	2018	DATE
admet-733	467	3	29	CARDINAL
admet-733	468	1	39	CARDINAL
admet-733	468	2	r. possemato	PERSON
admet-733	468	3	k.m. marks	ORG
admet-733	468	4	y.d. shaul	PERSON
admet-733	468	5	m.e.	GPE
admet-733	468	6	d. kim	PERSON
admet-733	468	7	k. birsoy	PERSON
admet-733	468	8	s. sethumadhavan	PERSON
admet-733	468	9	h.g. jang	PERSON
admet-733	468	10	jha	PERSON
admet-733	468	11	w.w. chen	GPE
admet-733	468	12	f.g. barrett	PERSON
admet-733	468	13	n. stransky	PERSON
admet-733	468	14	z.y. tsun	PERSON
admet-733	468	15	g.s. cowley	GPE
admet-733	468	16	j. barretina	PERSON
admet-733	468	17	n.y.	GPE
admet-733	468	18	kalaany	GPE
admet-733	468	19	hsu	PERSON
admet-733	468	20	k. ottina	PERSON
admet-733	468	21	chan	PERSON
admet-733	468	22	b. yuan	PERSON
admet-733	468	23	l.a	GPE
admet-733	468	24	garraway	PERSON
admet-733	468	25	d.e.	GPE
admet-733	468	26	m. mino-kenudson	PERSON
admet-733	468	27	e.f. brachtel	GPE
admet-733	468	28	e.m.	GPE
admet-733	468	29	sabatini	PERSON
admet-733	469	1	476	CARDINAL
admet-733	469	2	2011	DATE
admet-733	469	3	346	CARDINAL
admet-733	470	1	40	CARDINAL
admet-733	470	2	r.a. lerner	PERSON
admet-733	473	1	biochem	PERSON
admet-733	474	1	87	CARDINAL
admet-733	474	2	2018	DATE
admet-733	474	3	479	CARDINAL
admet-733	475	1	41	CARDINAL
admet-733	475	2	s. geschwindner	PERSON
admet-733	475	3	a. breeze	PERSON
admet-733	475	4	g. davies	PERSON
admet-733	475	5	n. colclough	PERSON
admet-733	475	6	d. temesi	PERSON
admet-733	479	1	1008	DATE
admet-733	479	2	2013	DATE
admet-733	479	3	327	CARDINAL
admet-733	480	1	2019	DATE
admet-733	480	2	iapc	ORG
admet-733	480	3	zagreb	GPE
admet-733	480	4	croatia	GPE
admet-733	481	1	http://creativecommons.org/licenses/by/3.0/	ORG
admet-733	481	2	http://creativecommons.org/licenses/by/3.0/	ORG