id	sid	tid	token	lemma	pos
admet-1271	1	1	recent	recent	ADJ
admet-1271	1	2	advances	advance	NOUN
admet-1271	1	3	and	and	CCONJ
admet-1271	1	4	challenges	challenge	NOUN
admet-1271	1	5	in	in	ADP
admet-1271	1	6	antibacterial	antibacterial	ADJ
admet-1271	1	7	drug	drug	NOUN
admet-1271	1	8	development	development	NOUN
admet-1271	1	9	doi	doi	PROPN
admet-1271	1	10	:	:	PUNCT
admet-1271	1	11	http://dx.doi.org/10.5599/admet.1271	http://dx.doi.org/10.5599/admet.1271	X
admet-1271	1	12	147	147	NUM
admet-1271	1	13	admet	admet	PROPN
admet-1271	1	14	&	&	CCONJ
admet-1271	1	15	dmpk	dmpk	PROPN
admet-1271	1	16	10(2	10(2	NUM
admet-1271	1	17	)	)	PUNCT
admet-1271	1	18	(	(	PUNCT
admet-1271	1	19	2022	2022	NUM
admet-1271	1	20	)	)	PUNCT
admet-1271	1	21	147	147	NUM
admet-1271	1	22	-	-	SYM
admet-1271	1	23	151	151	NUM
admet-1271	1	24	;	;	PUNCT
admet-1271	1	25	doi	doi	NOUN
admet-1271	1	26	:	:	PUNCT
admet-1271	1	27	https://doi.org/10.5599/admet.1271	https://doi.org/10.5599/admet.1271	NOUN
admet-1271	1	28	open	open	ADJ
admet-1271	1	29	access	access	NOUN
admet-1271	1	30	:	:	PUNCT
admet-1271	1	31	issn	issn	PROPN
admet-1271	1	32	:	:	PUNCT
admet-1271	1	33	1848	1848	NUM
admet-1271	1	34	-	-	SYM
admet-1271	1	35	7718	7718	NUM
admet-1271	1	36	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-1271	1	37	short	short	ADJ
admet-1271	1	38	communication	communication	NOUN
admet-1271	1	39	recent	recent	ADJ
admet-1271	1	40	advances	advance	NOUN
admet-1271	1	41	and	and	CCONJ
admet-1271	1	42	challenges	challenge	NOUN
admet-1271	1	43	in	in	ADP
admet-1271	1	44	antibacterial	antibacterial	ADJ
admet-1271	1	45	drug	drug	NOUN
admet-1271	1	46	development	development	PROPN
admet-1271	1	47	valeria	valeria	PROPN
admet-1271	1	48	gigante	gigante	PROPN
admet-1271	1	49	*	*	PROPN
admet-1271	1	50	,	,	PUNCT
admet-1271	1	51	hatim	hatim	PROPN
admet-1271	1	52	sati	sati	PROPN
admet-1271	1	53	,	,	PUNCT
admet-1271	1	54	and	and	CCONJ
admet-1271	1	55	peter	peter	PROPN
admet-1271	1	56	beyer1	beyer1	PROPN
admet-1271	1	57	impact	impact	PROPN
admet-1271	1	58	initiatives	initiative	NOUN
admet-1271	1	59	and	and	CCONJ
admet-1271	1	60	research	research	NOUN
admet-1271	1	61	coordination	coordination	NOUN
admet-1271	1	62	unit	unit	NOUN
admet-1271	1	63	,	,	PUNCT
admet-1271	1	64	global	global	ADJ
admet-1271	1	65	coordination	coordination	PROPN
admet-1271	1	66	department	department	PROPN
admet-1271	1	67	,	,	PUNCT
admet-1271	1	68	amr	amr	NOUN
admet-1271	1	69	division	division	NOUN
admet-1271	1	70	,	,	PUNCT
admet-1271	1	71	who	who	PRON
admet-1271	1	72	,	,	PUNCT
admet-1271	1	73	geneva	geneva	PROPN
admet-1271	1	74	,	,	PUNCT
admet-1271	1	75	switzerland	switzerland	PROPN
admet-1271	1	76	*	*	PUNCT
admet-1271	1	77	corresponding	correspond	VERB
admet-1271	1	78	author	author	NOUN
admet-1271	1	79	:	:	PUNCT
admet-1271	1	80	e	e	NOUN
admet-1271	1	81	-	-	NOUN
admet-1271	1	82	mail	mail	NOUN
admet-1271	1	83	:	:	PUNCT
admet-1271	1	84	gigantev@who.int	gigantev@who.int	NOUN
admet-1271	1	85	received	receive	VERB
admet-1271	1	86	:	:	PUNCT
admet-1271	1	87	january	january	PROPN
admet-1271	1	88	31	31	NUM
admet-1271	1	89	,	,	PUNCT
admet-1271	1	90	2022	2022	NUM
admet-1271	1	91	;	;	PUNCT
admet-1271	1	92	revised	revise	VERB
admet-1271	1	93	:	:	PUNCT
admet-1271	1	94	february	february	PROPN
admet-1271	1	95	13	13	NUM
admet-1271	1	96	,	,	PUNCT
admet-1271	1	97	2022	2022	NUM
admet-1271	1	98	;	;	PUNCT
admet-1271	1	99	published	publish	VERB
admet-1271	1	100	:	:	PUNCT
admet-1271	1	101	march	march	PROPN
admet-1271	1	102	04	04	NUM
admet-1271	1	103	,	,	PUNCT
admet-1271	1	104	2022	2022	NUM
admet-1271	1	105	keywords	keyword	NOUN
admet-1271	1	106	:	:	PUNCT
admet-1271	1	107	antimicrobial	antimicrobial	ADJ
admet-1271	1	108	resistance	resistance	NOUN
admet-1271	1	109	;	;	PUNCT
admet-1271	1	110	who	who	PRON
admet-1271	1	111	pipeline	pipeline	VERB
admet-1271	1	112	;	;	PUNCT
admet-1271	1	113	research	research	NOUN
admet-1271	1	114	and	and	CCONJ
admet-1271	1	115	development	development	NOUN
admet-1271	1	116	;	;	PUNCT
admet-1271	1	117	public	public	ADJ
admet-1271	1	118	health	health	NOUN
admet-1271	1	119	.	.	PUNCT
admet-1271	2	1	antimicrobial	antimicrobial	ADJ
admet-1271	2	2	resistance	resistance	NOUN
admet-1271	2	3	(	(	PUNCT
admet-1271	2	4	amr	amr	NOUN
admet-1271	2	5	)	)	PUNCT
admet-1271	2	6	is	be	AUX
admet-1271	2	7	one	one	NUM
admet-1271	2	8	of	of	ADP
admet-1271	2	9	the	the	DET
admet-1271	2	10	leading	lead	VERB
admet-1271	2	11	causes	cause	NOUN
admet-1271	2	12	of	of	ADP
admet-1271	2	13	death	death	NOUN
admet-1271	2	14	globally	globally	ADV
admet-1271	2	15	.	.	PUNCT
admet-1271	3	1	recent	recent	ADJ
admet-1271	3	2	estimates	estimate	NOUN
admet-1271	3	3	reveal	reveal	VERB
admet-1271	3	4	that	that	SCONJ
admet-1271	3	5	1.2	1.2	NUM
admet-1271	3	6	million	million	NUM
admet-1271	3	7	deaths	death	NOUN
admet-1271	3	8	were	be	AUX
admet-1271	3	9	due	due	ADJ
admet-1271	3	10	to	to	PART
admet-1271	3	11	resistant	resistant	VERB
admet-1271	3	12	bacterial	bacterial	ADJ
admet-1271	3	13	infections	infection	NOUN
admet-1271	3	14	in	in	ADP
admet-1271	3	15	2019	2019	NUM
admet-1271	3	16	and	and	CCONJ
admet-1271	3	17	4.95	4.95	NUM
admet-1271	3	18	million	million	NUM
admet-1271	3	19	deaths	death	NOUN
admet-1271	3	20	were	be	AUX
admet-1271	3	21	associated	associate	VERB
admet-1271	3	22	with	with	ADP
admet-1271	3	23	resistant	resistant	ADJ
admet-1271	3	24	bacterial	bacterial	ADJ
admet-1271	3	25	infections	infection	NOUN
admet-1271	3	26	[	[	X
admet-1271	3	27	1	1	NUM
admet-1271	3	28	]	]	PUNCT
admet-1271	3	29	.	.	PUNCT
admet-1271	4	1	there	there	PRON
admet-1271	4	2	are	be	VERB
admet-1271	4	3	some	some	DET
admet-1271	4	4	evidences	evidence	NOUN
admet-1271	4	5	suggesting	suggest	VERB
admet-1271	4	6	that	that	SCONJ
admet-1271	4	7	the	the	DET
admet-1271	4	8	current	current	ADJ
admet-1271	4	9	global	global	ADJ
admet-1271	4	10	crisis	crisis	NOUN
admet-1271	4	11	due	due	ADP
admet-1271	4	12	to	to	ADP
admet-1271	4	13	covid-19	covid-19	PROPN
admet-1271	4	14	pandemic	pandemic	NOUN
admet-1271	4	15	might	might	AUX
admet-1271	4	16	have	have	AUX
admet-1271	4	17	exacerbated	exacerbate	VERB
admet-1271	4	18	antibiotic	antibiotic	ADJ
admet-1271	4	19	use	use	NOUN
admet-1271	4	20	.	.	PUNCT
admet-1271	5	1	in	in	ADP
admet-1271	5	2	addition	addition	NOUN
admet-1271	5	3	,	,	PUNCT
admet-1271	5	4	the	the	DET
admet-1271	5	5	pandemic	pandemic	NOUN
admet-1271	5	6	has	have	AUX
admet-1271	5	7	marginalized	marginalize	VERB
admet-1271	5	8	many	many	ADJ
admet-1271	5	9	public	public	ADJ
admet-1271	5	10	health	health	NOUN
admet-1271	5	11	priorities	priority	NOUN
admet-1271	5	12	and	and	CCONJ
admet-1271	5	13	programs	program	NOUN
admet-1271	5	14	in	in	ADP
admet-1271	5	15	countries	country	NOUN
admet-1271	5	16	,	,	PUNCT
admet-1271	5	17	resulting	result	VERB
admet-1271	5	18	in	in	ADP
admet-1271	5	19	services	service	NOUN
admet-1271	5	20	and	and	CCONJ
admet-1271	5	21	programs	program	NOUN
admet-1271	5	22	interruption	interruption	NOUN
admet-1271	5	23	such	such	ADJ
admet-1271	5	24	as	as	ADP
admet-1271	5	25	disease	disease	NOUN
admet-1271	5	26	surveillance	surveillance	NOUN
admet-1271	5	27	.	.	PUNCT
admet-1271	6	1	this	this	PRON
admet-1271	6	2	all	all	PRON
admet-1271	6	3	together	together	ADV
admet-1271	6	4	threatens	threaten	VERB
admet-1271	6	5	the	the	DET
admet-1271	6	6	gains	gain	NOUN
admet-1271	6	7	made	make	VERB
admet-1271	6	8	in	in	ADP
admet-1271	6	9	recent	recent	ADJ
admet-1271	6	10	years	year	NOUN
admet-1271	6	11	against	against	ADP
admet-1271	6	12	amr	amr	NOUN
admet-1271	6	13	.	.	PROPN
admet-1271	7	1	this	this	PRON
admet-1271	7	2	includes	include	VERB
admet-1271	7	3	nourishing	nourish	VERB
admet-1271	7	4	the	the	DET
admet-1271	7	5	pipeline	pipeline	NOUN
admet-1271	7	6	,	,	PUNCT
admet-1271	7	7	investing	invest	VERB
admet-1271	7	8	in	in	ADP
admet-1271	7	9	the	the	DET
admet-1271	7	10	development	development	NOUN
admet-1271	7	11	of	of	ADP
admet-1271	7	12	new	new	ADJ
admet-1271	7	13	therapies	therapy	NOUN
admet-1271	7	14	knowing	know	VERB
admet-1271	7	15	that	that	SCONJ
admet-1271	7	16	research	research	NOUN
admet-1271	7	17	and	and	CCONJ
admet-1271	7	18	development	development	NOUN
admet-1271	7	19	(	(	PUNCT
admet-1271	7	20	r&d	r&d	NOUN
admet-1271	7	21	)	)	PUNCT
admet-1271	7	22	of	of	ADP
admet-1271	7	23	safe	safe	ADJ
admet-1271	7	24	and	and	CCONJ
admet-1271	7	25	effective	effective	ADJ
admet-1271	7	26	products	product	NOUN
admet-1271	7	27	takes	take	VERB
admet-1271	7	28	time	time	NOUN
admet-1271	7	29	,	,	PUNCT
admet-1271	7	30	and	and	CCONJ
admet-1271	7	31	adopting	adopt	VERB
admet-1271	7	32	policy	policy	NOUN
admet-1271	7	33	at	at	ADP
admet-1271	7	34	the	the	DET
admet-1271	7	35	government	government	NOUN
admet-1271	7	36	level	level	NOUN
admet-1271	7	37	such	such	ADJ
admet-1271	7	38	as	as	ADP
admet-1271	7	39	advanced	advanced	ADJ
admet-1271	7	40	remuneration	remuneration	NOUN
admet-1271	7	41	frameworks	framework	NOUN
admet-1271	7	42	to	to	PART
admet-1271	7	43	create	create	VERB
admet-1271	7	44	a	a	DET
admet-1271	7	45	viable	viable	ADJ
admet-1271	7	46	environment	environment	NOUN
admet-1271	7	47	for	for	ADP
admet-1271	7	48	new	new	ADJ
admet-1271	7	49	products	product	NOUN
admet-1271	7	50	[	[	X
admet-1271	7	51	2	2	NUM
admet-1271	7	52	]	]	PUNCT
admet-1271	7	53	.	.	PUNCT
admet-1271	8	1	since	since	SCONJ
admet-1271	8	2	2017	2017	NUM
admet-1271	8	3	world	world	NOUN
admet-1271	8	4	health	health	NOUN
admet-1271	8	5	organization	organization	NOUN
admet-1271	8	6	(	(	PUNCT
admet-1271	8	7	who	who	PRON
admet-1271	8	8	)	)	PUNCT
admet-1271	8	9	analyses	analyse	VERB
admet-1271	8	10	the	the	DET
admet-1271	8	11	antibacterial	antibacterial	ADJ
admet-1271	8	12	development	development	NOUN
admet-1271	8	13	pipeline	pipeline	NOUN
admet-1271	8	14	annually	annually	ADV
admet-1271	8	15	.	.	PUNCT
admet-1271	9	1	the	the	DET
admet-1271	9	2	analysis	analysis	NOUN
admet-1271	9	3	covers	cover	VERB
admet-1271	9	4	traditional	traditional	ADJ
admet-1271	9	5	direct	direct	ADJ
admet-1271	9	6	-	-	PUNCT
admet-1271	9	7	acting	act	VERB
admet-1271	9	8	small	small	ADJ
admet-1271	9	9	molecules	molecule	NOUN
admet-1271	9	10	and	and	CCONJ
admet-1271	9	11	nontraditional	nontraditional	ADJ
admet-1271	9	12	antibacterial	antibacterial	ADJ
admet-1271	9	13	agents	agent	NOUN
admet-1271	9	14	in	in	ADP
admet-1271	9	15	clinical	clinical	ADJ
admet-1271	9	16	and	and	CCONJ
admet-1271	9	17	preclinical	preclinical	ADJ
admet-1271	9	18	development	development	NOUN
admet-1271	9	19	worldwide	worldwide	ADV
admet-1271	9	20	.	.	PUNCT
admet-1271	10	1	the	the	DET
admet-1271	10	2	aim	aim	NOUN
admet-1271	10	3	is	be	AUX
admet-1271	10	4	to	to	PART
admet-1271	10	5	evaluate	evaluate	VERB
admet-1271	10	6	to	to	ADP
admet-1271	10	7	what	what	DET
admet-1271	10	8	extent	extent	NOUN
admet-1271	10	9	does	do	AUX
admet-1271	10	10	the	the	DET
admet-1271	10	11	present	present	ADJ
admet-1271	10	12	pipeline	pipeline	NOUN
admet-1271	10	13	address	address	VERB
admet-1271	10	14	the	the	DET
admet-1271	10	15	who	who	PRON
admet-1271	10	16	bacterial	bacterial	ADJ
admet-1271	10	17	priority	priority	NOUN
admet-1271	10	18	pathogens	pathogen	NOUN
admet-1271	10	19	,	,	PUNCT
admet-1271	10	20	mycobacterium	mycobacterium	NOUN
admet-1271	10	21	tuberculosis	tuberculosis	NOUN
admet-1271	10	22	and	and	CCONJ
admet-1271	10	23	clostridium	clostridium	NOUN
admet-1271	10	24	difficile	difficile	VERB
admet-1271	10	25	[	[	X
admet-1271	10	26	3	3	NUM
admet-1271	10	27	]	]	PUNCT
admet-1271	10	28	.	.	PUNCT
admet-1271	11	1	the	the	DET
admet-1271	11	2	end	end	NOUN
admet-1271	11	3	goal	goal	NOUN
admet-1271	11	4	is	be	AUX
admet-1271	11	5	to	to	PART
admet-1271	11	6	understand	understand	VERB
admet-1271	11	7	the	the	DET
admet-1271	11	8	state	state	NOUN
admet-1271	11	9	of	of	ADP
admet-1271	11	10	the	the	DET
admet-1271	11	11	pipeline	pipeline	NOUN
admet-1271	11	12	and	and	CCONJ
admet-1271	11	13	to	to	PART
admet-1271	11	14	direct	direct	VERB
admet-1271	11	15	r&d	r&d	NOUN
admet-1271	11	16	towards	towards	ADP
admet-1271	11	17	public	public	ADJ
admet-1271	11	18	health	health	NOUN
admet-1271	11	19	unmet	unmet	NOUN
admet-1271	11	20	needs	need	NOUN
admet-1271	11	21	.	.	PUNCT
admet-1271	12	1	today	today	NOUN
admet-1271	12	2	who	who	PRON
admet-1271	12	3	pipeline	pipeline	NOUN
admet-1271	12	4	review	review	NOUN
admet-1271	12	5	is	be	AUX
admet-1271	12	6	the	the	DET
admet-1271	12	7	only	only	ADJ
admet-1271	12	8	global	global	ADJ
admet-1271	12	9	analysis	analysis	NOUN
admet-1271	12	10	that	that	PRON
admet-1271	12	11	regularly	regularly	ADV
admet-1271	12	12	covers	cover	VERB
admet-1271	12	13	antibacterial	antibacterial	ADJ
admet-1271	12	14	agents	agent	NOUN
admet-1271	12	15	in	in	ADP
admet-1271	12	16	development	development	NOUN
admet-1271	12	17	by	by	ADP
admet-1271	12	18	large	large	ADJ
admet-1271	12	19	pharmaceutical	pharmaceutical	ADJ
admet-1271	12	20	companies	company	NOUN
admet-1271	12	21	as	as	ADV
admet-1271	12	22	well	well	ADV
admet-1271	12	23	as	as	ADP
admet-1271	12	24	by	by	ADP
admet-1271	12	25	medium	medium	ADJ
admet-1271	12	26	and	and	CCONJ
admet-1271	12	27	small	small	ADJ
admet-1271	12	28	size	size	NOUN
admet-1271	12	29	enterprises	enterprise	NOUN
admet-1271	12	30	[	[	X
admet-1271	12	31	4	4	NUM
admet-1271	12	32	]	]	PUNCT
admet-1271	12	33	.	.	PUNCT
admet-1271	13	1	findings	finding	NOUN
admet-1271	13	2	from	from	ADP
admet-1271	13	3	this	this	DET
admet-1271	13	4	analysis	analysis	NOUN
admet-1271	13	5	are	be	AUX
admet-1271	13	6	featured	feature	VERB
admet-1271	13	7	in	in	ADP
admet-1271	13	8	an	an	DET
admet-1271	13	9	annual	annual	ADJ
admet-1271	13	10	who	who	PRON
admet-1271	13	11	publication	publication	NOUN
admet-1271	13	12	and	and	CCONJ
admet-1271	13	13	the	the	DET
admet-1271	13	14	data	datum	NOUN
admet-1271	13	15	are	be	AUX
admet-1271	13	16	also	also	ADV
admet-1271	13	17	made	make	VERB
admet-1271	13	18	public	public	ADJ
admet-1271	13	19	through	through	ADP
admet-1271	13	20	who	who	PRON
admet-1271	13	21	r&d	r&d	VERB
admet-1271	13	22	observatory	observatory	NOUN
admet-1271	13	23	[	[	X
admet-1271	13	24	5	5	NUM
admet-1271	13	25	]	]	PUNCT
admet-1271	13	26	as	as	ADV
admet-1271	13	27	well	well	ADV
admet-1271	13	28	as	as	ADP
admet-1271	13	29	the	the	DET
admet-1271	13	30	global	global	ADJ
admet-1271	13	31	amr	amr	PROPN
admet-1271	13	32	r&d	r&d	PROPN
admet-1271	13	33	hub	hub	NOUN
admet-1271	13	34	.	.	PUNCT
admet-1271	14	1	overall	overall	ADV
admet-1271	14	2	,	,	PUNCT
admet-1271	14	3	this	this	DET
admet-1271	14	4	information	information	NOUN
admet-1271	14	5	allows	allow	VERB
admet-1271	14	6	for	for	ADP
admet-1271	14	7	secondary	secondary	ADJ
admet-1271	14	8	analyses	analysis	NOUN
admet-1271	14	9	such	such	ADJ
admet-1271	14	10	as	as	ADP
admet-1271	14	11	the	the	DET
admet-1271	14	12	estimation	estimation	NOUN
admet-1271	14	13	of	of	ADP
admet-1271	14	14	the	the	DET
admet-1271	14	15	source	source	NOUN
admet-1271	14	16	and	and	CCONJ
admet-1271	14	17	number	number	NOUN
admet-1271	14	18	of	of	ADP
admet-1271	14	19	investments	investment	NOUN
admet-1271	14	20	across	across	ADP
admet-1271	14	21	the	the	DET
admet-1271	14	22	different	different	ADJ
admet-1271	14	23	development	development	NOUN
admet-1271	14	24	phases	phase	NOUN
admet-1271	14	25	as	as	SCONJ
admet-1271	14	26	shown	show	VERB
admet-1271	14	27	in	in	ADP
admet-1271	14	28	the	the	DET
admet-1271	14	29	global	global	ADJ
admet-1271	14	30	amr	amr	PROPN
admet-1271	14	31	r&d	r&d	NOUN
admet-1271	14	32	hub	hub	NOUN
admet-1271	14	33	dashboard	dashboard	NOUN
admet-1271	14	34	[	[	X
admet-1271	14	35	6,7	6,7	NUM
admet-1271	14	36	]	]	PUNCT
admet-1271	14	37	.	.	PUNCT
admet-1271	15	1	the	the	DET
admet-1271	15	2	long	long	ADJ
admet-1271	15	3	road	road	NOUN
admet-1271	15	4	to	to	ADP
admet-1271	15	5	approval	approval	NOUN
admet-1271	15	6	between	between	ADP
admet-1271	15	7	july	july	PROPN
admet-1271	15	8	2017	2017	NUM
admet-1271	15	9	and	and	CCONJ
admet-1271	15	10	november	november	PROPN
admet-1271	15	11	2021	2021	NUM
admet-1271	15	12	,	,	PUNCT
admet-1271	15	13	twelve	twelve	NUM
admet-1271	15	14	new	new	ADJ
admet-1271	15	15	antibacterial	antibacterial	ADJ
admet-1271	15	16	agents	agent	NOUN
admet-1271	15	17	have	have	AUX
admet-1271	15	18	been	be	AUX
admet-1271	15	19	approved	approve	VERB
admet-1271	15	20	by	by	ADP
admet-1271	15	21	either	either	CCONJ
admet-1271	15	22	the	the	DET
admet-1271	15	23	us	us	PROPN
admet-1271	15	24	food	food	NOUN
admet-1271	15	25	and	and	CCONJ
admet-1271	15	26	drug	drug	PROPN
admet-1271	15	27	administration	administration	PROPN
admet-1271	15	28	(	(	PUNCT
admet-1271	15	29	fda	fda	PROPN
admet-1271	15	30	)	)	PUNCT
admet-1271	15	31	,	,	PUNCT
admet-1271	15	32	the	the	DET
admet-1271	15	33	european	european	PROPN
admet-1271	15	34	medicines	medicines	PROPN
admet-1271	15	35	agency	agency	NOUN
admet-1271	15	36	(	(	PUNCT
admet-1271	15	37	ema	ema	PROPN
admet-1271	15	38	)	)	PUNCT
admet-1271	15	39	,	,	PUNCT
admet-1271	15	40	or	or	CCONJ
admet-1271	15	41	both	both	PRON
admet-1271	15	42	.	.	PUNCT
admet-1271	16	1	only	only	ADV
admet-1271	16	2	one	one	NUM
admet-1271	16	3	of	of	ADP
admet-1271	16	4	1	1	NUM
admet-1271	16	5	the	the	DET
admet-1271	16	6	authors	author	NOUN
admet-1271	16	7	are	be	AUX
admet-1271	16	8	staff	staff	NOUN
admet-1271	16	9	members	member	NOUN
admet-1271	16	10	of	of	ADP
admet-1271	16	11	the	the	DET
admet-1271	16	12	world	world	PROPN
admet-1271	16	13	health	health	PROPN
admet-1271	16	14	organization	organization	NOUN
admet-1271	16	15	.	.	PUNCT
admet-1271	17	1	the	the	DET
admet-1271	17	2	authors	author	NOUN
admet-1271	17	3	alone	alone	ADV
admet-1271	17	4	are	be	AUX
admet-1271	17	5	responsible	responsible	ADJ
admet-1271	17	6	for	for	ADP
admet-1271	17	7	the	the	DET
admet-1271	17	8	views	view	NOUN
admet-1271	17	9	expressed	express	VERB
admet-1271	17	10	in	in	ADP
admet-1271	17	11	this	this	DET
admet-1271	17	12	article	article	NOUN
admet-1271	17	13	and	and	CCONJ
admet-1271	17	14	they	they	PRON
admet-1271	17	15	do	do	AUX
admet-1271	17	16	not	not	PART
admet-1271	17	17	necessarily	necessarily	ADV
admet-1271	17	18	represent	represent	VERB
admet-1271	17	19	the	the	DET
admet-1271	17	20	decisions	decision	NOUN
admet-1271	17	21	,	,	PUNCT
admet-1271	17	22	policy	policy	NOUN
admet-1271	17	23	or	or	CCONJ
admet-1271	17	24	views	view	NOUN
admet-1271	17	25	of	of	ADP
admet-1271	17	26	the	the	DET
admet-1271	17	27	world	world	PROPN
admet-1271	17	28	health	health	NOUN
admet-1271	17	29	organization	organization	NOUN
admet-1271	17	30	http://dx.doi.org/10.5599/admet.1271	http://dx.doi.org/10.5599/admet.1271	PUNCT
admet-1271	17	31	https://doi.org/10.5599/admet.1271	https://doi.org/10.5599/admet.1271	X
admet-1271	17	32	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-1271	17	33	mailto	mailto	NOUN
admet-1271	17	34	:	:	PUNCT
admet-1271	17	35	gigantev@who.int%20n	gigantev@who.int%20n	PROPN
admet-1271	17	36	gigante	gigante	PROPN
admet-1271	17	37	,	,	PUNCT
admet-1271	17	38	sati	sati	PROPN
admet-1271	17	39	and	and	CCONJ
admet-1271	17	40	beyer	beyer	PROPN
admet-1271	17	41	admet	admet	PROPN
admet-1271	17	42	&	&	CCONJ
admet-1271	17	43	dmpk	dmpk	PROPN
admet-1271	17	44	10(2	10(2	NUM
admet-1271	17	45	)	)	PUNCT
admet-1271	17	46	(	(	PUNCT
admet-1271	17	47	2022	2022	NUM
admet-1271	17	48	)	)	PUNCT
admet-1271	17	49	147	147	NUM
admet-1271	17	50	-	-	SYM
admet-1271	17	51	151	151	NUM
admet-1271	17	52	148	148	NUM
admet-1271	17	53	these	these	PRON
admet-1271	17	54	was	be	AUX
admet-1271	17	55	approved	approve	VERB
admet-1271	17	56	in	in	ADP
admet-1271	17	57	the	the	DET
admet-1271	17	58	last	last	ADJ
admet-1271	17	59	two	two	NUM
admet-1271	17	60	years	year	NOUN
admet-1271	17	61	.	.	PUNCT
admet-1271	18	1	this	this	PRON
admet-1271	18	2	translates	translate	VERB
admet-1271	18	3	to	to	ADP
admet-1271	18	4	an	an	DET
admet-1271	18	5	average	average	ADJ
admet-1271	18	6	duration	duration	NOUN
admet-1271	18	7	of	of	ADP
admet-1271	18	8	approximately	approximately	ADV
admet-1271	18	9	10.1	10.1	NUM
admet-1271	18	10	years	year	NOUN
admet-1271	18	11	for	for	SCONJ
admet-1271	18	12	a	a	DET
admet-1271	18	13	new	new	ADJ
admet-1271	18	14	antimicrobial	antimicrobial	ADJ
admet-1271	18	15	agent	agent	NOUN
admet-1271	18	16	to	to	PART
admet-1271	18	17	advance	advance	VERB
admet-1271	18	18	from	from	ADP
admet-1271	18	19	the	the	DET
admet-1271	18	20	discovery	discovery	NOUN
admet-1271	18	21	and	and	CCONJ
admet-1271	18	22	preclinical	preclinical	ADJ
admet-1271	18	23	stage	stage	NOUN
admet-1271	18	24	until	until	ADP
admet-1271	18	25	the	the	DET
admet-1271	18	26	market	market	NOUN
admet-1271	18	27	authorization	authorization	NOUN
admet-1271	18	28	[	[	X
admet-1271	18	29	8	8	NUM
admet-1271	18	30	]	]	PUNCT
admet-1271	18	31	.	.	PUNCT
admet-1271	19	1	looking	look	VERB
admet-1271	19	2	at	at	ADP
admet-1271	19	3	the	the	DET
admet-1271	19	4	progression	progression	NOUN
admet-1271	19	5	rate	rate	NOUN
admet-1271	19	6	,	,	PUNCT
admet-1271	19	7	a	a	PRON
admet-1271	19	8	who	who	PRON
admet-1271	19	9	financial	financial	ADJ
admet-1271	19	10	model	model	NOUN
admet-1271	19	11	estimates	estimate	VERB
admet-1271	19	12	that	that	SCONJ
admet-1271	19	13	an	an	DET
admet-1271	19	14	antibacterial	antibacterial	ADJ
admet-1271	19	15	product	product	NOUN
admet-1271	19	16	in	in	ADP
admet-1271	19	17	preclinical	preclinical	ADJ
admet-1271	19	18	development	development	NOUN
admet-1271	19	19	has	have	VERB
admet-1271	19	20	approximately	approximately	ADV
admet-1271	19	21	a	a	DET
admet-1271	19	22	12.5	12.5	NUM
admet-1271	19	23	%	%	NOUN
admet-1271	19	24	chance	chance	NOUN
admet-1271	19	25	of	of	ADP
admet-1271	19	26	successfully	successfully	ADV
admet-1271	19	27	moving	move	VERB
admet-1271	19	28	past	past	ADP
admet-1271	19	29	the	the	DET
admet-1271	19	30	registration	registration	NOUN
admet-1271	19	31	phase	phase	NOUN
admet-1271	19	32	[	[	X
admet-1271	19	33	8	8	NUM
admet-1271	19	34	]	]	PUNCT
admet-1271	19	35	.	.	PUNCT
admet-1271	20	1	these	these	DET
admet-1271	20	2	estimations	estimation	NOUN
admet-1271	20	3	reflect	reflect	VERB
admet-1271	20	4	the	the	DET
admet-1271	20	5	scientific	scientific	ADJ
admet-1271	20	6	complexity	complexity	NOUN
admet-1271	20	7	of	of	ADP
admet-1271	20	8	developing	develop	VERB
admet-1271	20	9	new	new	ADJ
admet-1271	20	10	drug	drug	NOUN
admet-1271	20	11	.	.	PUNCT
admet-1271	21	1	several	several	ADJ
admet-1271	21	2	factors	factor	NOUN
admet-1271	21	3	make	make	VERB
admet-1271	21	4	the	the	DET
admet-1271	21	5	development	development	NOUN
admet-1271	21	6	of	of	ADP
admet-1271	21	7	innovative	innovative	ADJ
admet-1271	21	8	antibacterials	antibacterial	NOUN
admet-1271	21	9	specifically	specifically	ADV
admet-1271	21	10	challenging	challenging	ADJ
admet-1271	21	11	.	.	PUNCT
admet-1271	22	1	these	these	PRON
admet-1271	22	2	include	include	VERB
admet-1271	22	3	the	the	DET
admet-1271	22	4	limited	limited	ADJ
admet-1271	22	5	funding	funding	NOUN
admet-1271	22	6	,	,	PUNCT
admet-1271	22	7	and	and	CCONJ
admet-1271	22	8	the	the	DET
admet-1271	22	9	limited	limited	ADJ
admet-1271	22	10	return	return	NOUN
admet-1271	22	11	on	on	ADP
admet-1271	22	12	investment	investment	NOUN
admet-1271	22	13	in	in	ADP
admet-1271	22	14	the	the	DET
admet-1271	22	15	current	current	ADJ
admet-1271	22	16	volume	volume	NOUN
admet-1271	22	17	-	-	PUNCT
admet-1271	22	18	driven	drive	VERB
admet-1271	22	19	revenue	revenue	NOUN
admet-1271	22	20	models	model	NOUN
admet-1271	22	21	.	.	PUNCT
admet-1271	23	1	this	this	PRON
admet-1271	23	2	is	be	AUX
admet-1271	23	3	exacerbated	exacerbate	VERB
admet-1271	23	4	by	by	ADP
admet-1271	23	5	the	the	DET
admet-1271	23	6	current	current	ADJ
admet-1271	23	7	epidemic	epidemic	NOUN
admet-1271	23	8	that	that	PRON
admet-1271	23	9	has	have	AUX
admet-1271	23	10	slowed	slow	VERB
admet-1271	23	11	down	down	ADP
admet-1271	23	12	and	and	CCONJ
admet-1271	23	13	even	even	ADV
admet-1271	23	14	halted	halt	VERB
admet-1271	23	15	many	many	ADJ
admet-1271	23	16	clinical	clinical	ADJ
admet-1271	23	17	and	and	CCONJ
admet-1271	23	18	preclinical	preclinical	ADJ
admet-1271	23	19	programmes	programme	NOUN
admet-1271	23	20	.	.	PUNCT
admet-1271	24	1	however	however	ADV
admet-1271	24	2	,	,	PUNCT
admet-1271	24	3	covid-19	covid-19	PROPN
admet-1271	24	4	could	could	AUX
admet-1271	24	5	be	be	AUX
admet-1271	24	6	looked	look	VERB
admet-1271	24	7	at	at	ADP
admet-1271	24	8	as	as	ADP
admet-1271	24	9	an	an	DET
admet-1271	24	10	opportunity	opportunity	NOUN
admet-1271	24	11	to	to	PART
admet-1271	24	12	push	push	VERB
admet-1271	24	13	for	for	ADP
admet-1271	24	14	ad	ad	NOUN
admet-1271	24	15	-	-	PUNCT
admet-1271	24	16	hoc	hoc	X
admet-1271	24	17	regulatory	regulatory	ADJ
admet-1271	24	18	pathways	pathway	NOUN
admet-1271	24	19	,	,	PUNCT
admet-1271	24	20	sustainable	sustainable	ADJ
admet-1271	24	21	public	public	ADJ
admet-1271	24	22	financial	financial	ADJ
admet-1271	24	23	models	model	NOUN
admet-1271	24	24	,	,	PUNCT
admet-1271	24	25	and	and	CCONJ
admet-1271	24	26	other	other	ADJ
admet-1271	24	27	financial	financial	ADJ
admet-1271	24	28	incentives	incentive	NOUN
admet-1271	24	29	that	that	PRON
admet-1271	24	30	prioritize	prioritize	VERB
admet-1271	24	31	antibacterial	antibacterial	ADJ
admet-1271	24	32	agents	agent	NOUN
admet-1271	24	33	as	as	ADP
admet-1271	24	34	a	a	DET
admet-1271	24	35	finite	finite	ADJ
admet-1271	24	36	public	public	ADJ
admet-1271	24	37	resource	resource	NOUN
admet-1271	24	38	.	.	PUNCT
admet-1271	25	1	this	this	DET
admet-1271	25	2	push	push	NOUN
admet-1271	25	3	could	could	AUX
admet-1271	25	4	also	also	ADV
admet-1271	25	5	include	include	VERB
admet-1271	25	6	investments	investment	NOUN
admet-1271	25	7	in	in	ADP
admet-1271	25	8	new	new	ADJ
admet-1271	25	9	emerging	emerge	VERB
admet-1271	25	10	technologies	technology	NOUN
admet-1271	25	11	and	and	CCONJ
admet-1271	25	12	nontraditional	nontraditional	ADJ
admet-1271	25	13	approaches	approach	NOUN
admet-1271	25	14	such	such	ADJ
admet-1271	25	15	as	as	ADP
admet-1271	25	16	synthetic	synthetic	ADJ
admet-1271	25	17	mrnas	mrna	NOUN
admet-1271	25	18	/	/	SYM
admet-1271	25	19	antimicrobial	antimicrobial	ADJ
admet-1271	25	20	peptides	peptide	NOUN
admet-1271	25	21	(	(	PUNCT
admet-1271	25	22	amps	amp	NOUN
admet-1271	25	23	)	)	PUNCT
admet-1271	25	24	and	and	CCONJ
admet-1271	25	25	phage	phage	NOUN
admet-1271	25	26	therapies	therapy	NOUN
admet-1271	25	27	.	.	PUNCT
admet-1271	26	1	surviving	survive	VERB
admet-1271	26	2	the	the	DET
admet-1271	26	3	market	market	NOUN
admet-1271	26	4	and	and	CCONJ
admet-1271	26	5	proving	prove	VERB
admet-1271	26	6	the	the	DET
admet-1271	26	7	value	value	NOUN
admet-1271	26	8	evaluating	evaluate	VERB
admet-1271	26	9	how	how	SCONJ
admet-1271	26	10	the	the	DET
admet-1271	26	11	newly	newly	ADV
admet-1271	26	12	approved	approve	VERB
admet-1271	26	13	products	product	NOUN
admet-1271	26	14	address	address	VERB
admet-1271	26	15	global	global	ADJ
admet-1271	26	16	public	public	ADJ
admet-1271	26	17	health	health	NOUN
admet-1271	26	18	priorities	priority	NOUN
admet-1271	26	19	,	,	PUNCT
admet-1271	26	20	only	only	ADV
admet-1271	26	21	one	one	NUM
admet-1271	26	22	agent	agent	NOUN
admet-1271	26	23	,	,	PUNCT
admet-1271	26	24	cefiderocol	cefiderocol	PROPN
admet-1271	26	25	,	,	PUNCT
admet-1271	26	26	is	be	AUX
admet-1271	26	27	said	say	VERB
admet-1271	26	28	to	to	PART
admet-1271	26	29	be	be	AUX
admet-1271	26	30	active	active	ADJ
admet-1271	26	31	against	against	ADP
admet-1271	26	32	all	all	DET
admet-1271	26	33	three	three	NUM
admet-1271	26	34	“	"	PUNCT
admet-1271	26	35	critical	critical	ADJ
admet-1271	26	36	”	"	PUNCT
admet-1271	26	37	gram	gram	NOUN
admet-1271	26	38	-	-	PUNCT
admet-1271	26	39	negative	negative	ADJ
admet-1271	26	40	bacteria	bacteria	NOUN
admet-1271	26	41	.	.	PUNCT
admet-1271	27	1	almost	almost	ADV
admet-1271	27	2	50	50	NUM
admet-1271	27	3	%	%	NOUN
admet-1271	27	4	of	of	ADP
admet-1271	27	5	the	the	DET
admet-1271	27	6	newly	newly	ADV
admet-1271	27	7	approved	approve	VERB
admet-1271	27	8	agents	agent	NOUN
admet-1271	27	9	(	(	PUNCT
admet-1271	27	10	n	n	NOUN
admet-1271	27	11	=	=	SYM
admet-1271	27	12	5	5	NUM
admet-1271	27	13	)	)	PUNCT
admet-1271	27	14	target	target	NOUN
admet-1271	27	15	one	one	NUM
admet-1271	27	16	priority	priority	NOUN
admet-1271	27	17	pathogen	pathogen	NOUN
admet-1271	27	18	in	in	ADP
admet-1271	27	19	the	the	DET
admet-1271	27	20	critical	critical	ADJ
admet-1271	27	21	category	category	NOUN
admet-1271	27	22	,	,	PUNCT
admet-1271	27	23	carbapenem	carbapenem	NOUN
admet-1271	27	24	-	-	PUNCT
admet-1271	27	25	resistant	resistant	ADJ
admet-1271	27	26	enterobacterales	enterobacterale	NOUN
admet-1271	27	27	(	(	PUNCT
admet-1271	27	28	cre	cre	PROPN
admet-1271	27	29	)	)	PUNCT
admet-1271	27	30	.	.	PUNCT
admet-1271	28	1	this	this	PRON
admet-1271	28	2	leaves	leave	VERB
admet-1271	28	3	two	two	NUM
admet-1271	28	4	critical	critical	ADJ
admet-1271	28	5	targets	target	NOUN
admet-1271	28	6	;	;	PUNCT
admet-1271	28	7	carbapenem	carbapenem	NOUN
admet-1271	28	8	-	-	PUNCT
admet-1271	28	9	resistant	resistant	ADJ
admet-1271	28	10	acinetobacter	acinetobacter	ADJ
admet-1271	28	11	baumannii	baumannii	ADJ
admet-1271	28	12	(	(	PUNCT
admet-1271	28	13	crab	crab	NOUN
admet-1271	28	14	)	)	PUNCT
admet-1271	28	15	and	and	CCONJ
admet-1271	28	16	carbapenem	carbapenem	NOUN
admet-1271	28	17	-	-	PUNCT
admet-1271	28	18	resistant	resistant	ADJ
admet-1271	28	19	pseudomonas	pseudomona	NOUN
admet-1271	28	20	aeruginosa	aeruginosa	NOUN
admet-1271	28	21	(	(	PUNCT
admet-1271	28	22	crpa	crpa	NOUN
admet-1271	28	23	)	)	PUNCT
admet-1271	28	24	,	,	PUNCT
admet-1271	28	25	largely	largely	ADV
admet-1271	28	26	unaddressed	unaddresse	VERB
admet-1271	28	27	at	at	ADP
admet-1271	28	28	present	present	NOUN
admet-1271	28	29	.	.	PUNCT
admet-1271	29	1	with	with	ADP
admet-1271	29	2	some	some	DET
admet-1271	29	3	exceptions	exception	NOUN
admet-1271	29	4	,	,	PUNCT
admet-1271	29	5	all	all	DET
admet-1271	29	6	newly	newly	ADV
admet-1271	29	7	approved	approve	VERB
admet-1271	29	8	agents	agent	NOUN
admet-1271	29	9	present	present	VERB
admet-1271	29	10	limited	limited	ADJ
admet-1271	29	11	clinical	clinical	ADJ
admet-1271	29	12	benefit	benefit	NOUN
admet-1271	29	13	over	over	ADP
admet-1271	29	14	existing	exist	VERB
admet-1271	29	15	treatment	treatment	NOUN
admet-1271	29	16	.	.	PUNCT
admet-1271	30	1	over	over	ADP
admet-1271	30	2	80	80	NUM
admet-1271	30	3	%	%	NOUN
admet-1271	30	4	of	of	ADP
admet-1271	30	5	the	the	DET
admet-1271	30	6	newly	newly	ADV
admet-1271	30	7	approved	approve	VERB
admet-1271	30	8	antibacterials	antibacterial	NOUN
admet-1271	30	9	belong	belong	VERB
admet-1271	30	10	to	to	ADP
admet-1271	30	11	existing	exist	VERB
admet-1271	30	12	classes	class	NOUN
admet-1271	30	13	(	(	PUNCT
admet-1271	30	14	mostly	mostly	ADV
admet-1271	30	15	ßlactamases	ßlactamase	NOUN
admet-1271	30	16	)	)	PUNCT
admet-1271	30	17	where	where	SCONJ
admet-1271	30	18	resistance	resistance	NOUN
admet-1271	30	19	mechanisms	mechanism	NOUN
admet-1271	30	20	are	be	AUX
admet-1271	30	21	well	well	ADV
admet-1271	30	22	established	establish	VERB
admet-1271	30	23	,	,	PUNCT
admet-1271	30	24	and	and	CCONJ
admet-1271	30	25	the	the	DET
admet-1271	30	26	development	development	NOUN
admet-1271	30	27	of	of	ADP
admet-1271	30	28	resistance	resistance	NOUN
admet-1271	30	29	is	be	AUX
admet-1271	30	30	expected	expect	VERB
admet-1271	30	31	.	.	PUNCT
admet-1271	31	1	the	the	DET
admet-1271	31	2	evident	evident	ADJ
admet-1271	31	3	challenge	challenge	NOUN
admet-1271	31	4	to	to	PART
admet-1271	31	5	design	design	VERB
admet-1271	31	6	new	new	ADJ
admet-1271	31	7	antibacterial	antibacterial	ADJ
admet-1271	31	8	classes	class	NOUN
admet-1271	31	9	calls	call	VERB
admet-1271	31	10	for	for	ADP
admet-1271	31	11	prudent	prudent	ADJ
admet-1271	31	12	use	use	NOUN
admet-1271	31	13	of	of	ADP
admet-1271	31	14	the	the	DET
admet-1271	31	15	existing	exist	VERB
admet-1271	31	16	agents	agent	NOUN
admet-1271	31	17	to	to	PART
admet-1271	31	18	ensure	ensure	VERB
admet-1271	31	19	their	their	PRON
admet-1271	31	20	longevity	longevity	NOUN
admet-1271	31	21	.	.	PUNCT
admet-1271	32	1	in	in	ADP
admet-1271	32	2	fact	fact	NOUN
admet-1271	32	3	,	,	PUNCT
admet-1271	32	4	the	the	DET
admet-1271	32	5	majority	majority	NOUN
admet-1271	32	6	(	(	PUNCT
admet-1271	32	7	7	7	NUM
admet-1271	32	8	out	out	ADP
admet-1271	32	9	of	of	ADP
admet-1271	32	10	12	12	NUM
admet-1271	32	11	)	)	PUNCT
admet-1271	32	12	of	of	ADP
admet-1271	32	13	the	the	DET
admet-1271	32	14	newly	newly	ADV
admet-1271	32	15	approved	approve	VERB
admet-1271	32	16	antibiotics	antibiotic	NOUN
admet-1271	32	17	are	be	AUX
admet-1271	32	18	classified	classify	VERB
admet-1271	32	19	as	as	ADP
admet-1271	32	20	“	"	PUNCT
admet-1271	32	21	reserve	reserve	NOUN
admet-1271	32	22	”	"	PUNCT
admet-1271	32	23	according	accord	VERB
admet-1271	32	24	to	to	ADP
admet-1271	32	25	the	the	DET
admet-1271	32	26	most	most	ADV
admet-1271	32	27	recent	recent	ADJ
admet-1271	32	28	who	who	PRON
admet-1271	32	29	aware	aware	ADJ
admet-1271	32	30	classification	classification	NOUN
admet-1271	32	31	,	,	PUNCT
admet-1271	32	32	while	while	SCONJ
admet-1271	32	33	three	three	NUM
admet-1271	32	34	are	be	AUX
admet-1271	32	35	in	in	ADP
admet-1271	32	36	the	the	DET
admet-1271	32	37	“	"	PUNCT
admet-1271	32	38	watch	watch	NOUN
admet-1271	32	39	”	"	PUNCT
admet-1271	32	40	group	group	NOUN
admet-1271	33	1	[	[	X
admet-1271	33	2	9,10	9,10	NUM
admet-1271	33	3	]	]	X
admet-1271	33	4	.	.	PUNCT
admet-1271	34	1	one	one	NUM
admet-1271	34	2	agent	agent	NOUN
admet-1271	34	3	,	,	PUNCT
admet-1271	34	4	contezolid	contezolid	NOUN
admet-1271	34	5	has	have	AUX
admet-1271	34	6	not	not	PART
admet-1271	34	7	been	be	AUX
admet-1271	34	8	classified	classify	VERB
admet-1271	34	9	at	at	ADP
admet-1271	34	10	the	the	DET
admet-1271	34	11	time	time	NOUN
admet-1271	34	12	of	of	ADP
admet-1271	34	13	this	this	DET
admet-1271	34	14	publication	publication	NOUN
admet-1271	34	15	,	,	PUNCT
admet-1271	34	16	but	but	CCONJ
admet-1271	34	17	like	like	ADP
admet-1271	34	18	other	other	ADJ
admet-1271	34	19	oxazolidinones	oxazolidinone	NOUN
admet-1271	34	20	,	,	PUNCT
admet-1271	34	21	is	be	AUX
admet-1271	34	22	expected	expect	VERB
admet-1271	34	23	to	to	PART
admet-1271	34	24	be	be	AUX
admet-1271	34	25	included	include	VERB
admet-1271	34	26	in	in	ADP
admet-1271	34	27	the	the	DET
admet-1271	34	28	“	"	PUNCT
admet-1271	34	29	reserve	reserve	NOUN
admet-1271	34	30	”	"	PUNCT
admet-1271	34	31	group	group	NOUN
admet-1271	34	32	in	in	ADP
admet-1271	34	33	the	the	DET
admet-1271	34	34	next	next	ADJ
admet-1271	34	35	iteration	iteration	NOUN
admet-1271	34	36	of	of	ADP
admet-1271	34	37	the	the	DET
admet-1271	34	38	aware	aware	ADJ
admet-1271	34	39	classification	classification	NOUN
admet-1271	35	1	[	[	X
admet-1271	35	2	10	10	NUM
admet-1271	35	3	]	]	PUNCT
admet-1271	35	4	.	.	PUNCT
admet-1271	36	1	this	this	PRON
admet-1271	36	2	also	also	ADV
admet-1271	36	3	indicates	indicate	VERB
admet-1271	36	4	that	that	SCONJ
admet-1271	36	5	most	most	ADJ
admet-1271	36	6	new	new	ADJ
admet-1271	36	7	agents	agent	NOUN
admet-1271	36	8	presently	presently	ADV
admet-1271	36	9	in	in	ADP
admet-1271	36	10	development	development	NOUN
admet-1271	36	11	,	,	PUNCT
admet-1271	36	12	when	when	SCONJ
admet-1271	36	13	approved	approve	VERB
admet-1271	36	14	,	,	PUNCT
admet-1271	36	15	will	will	AUX
admet-1271	36	16	likely	likely	ADV
admet-1271	36	17	be	be	AUX
admet-1271	36	18	in	in	ADP
admet-1271	36	19	the	the	DET
admet-1271	36	20	reserve	reserve	NOUN
admet-1271	36	21	group	group	NOUN
admet-1271	36	22	of	of	ADP
admet-1271	36	23	antibiotics	antibiotic	NOUN
admet-1271	36	24	to	to	PART
admet-1271	36	25	be	be	AUX
admet-1271	36	26	used	use	VERB
admet-1271	36	27	only	only	ADV
admet-1271	36	28	when	when	SCONJ
admet-1271	36	29	other	other	ADJ
admet-1271	36	30	treatment	treatment	NOUN
admet-1271	36	31	lines	line	NOUN
admet-1271	36	32	have	have	AUX
admet-1271	36	33	failed	fail	VERB
admet-1271	36	34	.	.	PUNCT
admet-1271	37	1	this	this	PRON
admet-1271	37	2	need	need	VERB
admet-1271	37	3	to	to	PART
admet-1271	37	4	preserve	preserve	VERB
admet-1271	37	5	new	new	ADJ
admet-1271	37	6	agents	agent	NOUN
admet-1271	37	7	is	be	AUX
admet-1271	37	8	another	another	DET
admet-1271	37	9	challenge	challenge	NOUN
admet-1271	37	10	to	to	ADP
admet-1271	37	11	antibacterial	antibacterial	ADJ
admet-1271	37	12	development	development	NOUN
admet-1271	37	13	that	that	PRON
admet-1271	37	14	could	could	AUX
admet-1271	37	15	further	far	ADV
admet-1271	37	16	limit	limit	VERB
admet-1271	37	17	investments	investment	NOUN
admet-1271	37	18	.	.	PUNCT
admet-1271	38	1	it	it	PRON
admet-1271	38	2	also	also	ADV
admet-1271	38	3	highlights	highlight	VERB
admet-1271	38	4	the	the	DET
admet-1271	38	5	need	need	NOUN
admet-1271	38	6	for	for	ADP
admet-1271	38	7	universal	universal	ADJ
admet-1271	38	8	decoupled	decouple	VERB
admet-1271	38	9	public	public	ADJ
admet-1271	38	10	financial	financial	ADJ
admet-1271	38	11	model(s	model(s	NOUN
admet-1271	38	12	)	)	PUNCT
admet-1271	38	13	through	through	ADP
admet-1271	38	14	existing	exist	VERB
admet-1271	38	15	push	push	NOUN
admet-1271	38	16	or	or	CCONJ
admet-1271	38	17	new	new	ADJ
admet-1271	38	18	pull	pull	NOUN
admet-1271	38	19	mechanisms	mechanism	NOUN
admet-1271	38	20	for	for	ADP
admet-1271	38	21	antibacterial	antibacterial	ADJ
admet-1271	38	22	drug	drug	NOUN
admet-1271	38	23	development	development	NOUN
admet-1271	38	24	.	.	PUNCT
admet-1271	39	1	however	however	ADV
admet-1271	39	2	,	,	PUNCT
admet-1271	39	3	to	to	PART
admet-1271	39	4	justify	justify	VERB
admet-1271	39	5	public	public	ADJ
admet-1271	39	6	funding	funding	NOUN
admet-1271	39	7	,	,	PUNCT
admet-1271	39	8	antimicrobial	antimicrobial	ADJ
admet-1271	39	9	programs	program	NOUN
admet-1271	39	10	need	need	VERB
admet-1271	39	11	to	to	PART
admet-1271	39	12	demonstrate	demonstrate	VERB
admet-1271	39	13	potential	potential	ADJ
admet-1271	39	14	clinical	clinical	ADJ
admet-1271	39	15	utility	utility	NOUN
admet-1271	39	16	of	of	ADP
admet-1271	39	17	candidates	candidate	NOUN
admet-1271	39	18	and	and	CCONJ
admet-1271	39	19	ideally	ideally	ADV
admet-1271	39	20	novelty	novelty	NOUN
admet-1271	39	21	,	,	PUNCT
admet-1271	39	22	by	by	ADP
admet-1271	39	23	moving	move	VERB
admet-1271	39	24	away	away	ADV
admet-1271	39	25	from	from	ADP
admet-1271	39	26	the	the	DET
admet-1271	39	27	development	development	NOUN
admet-1271	39	28	of	of	ADP
admet-1271	39	29	worn	worn	ADJ
admet-1271	39	30	derivatives	derivative	NOUN
admet-1271	39	31	with	with	ADP
admet-1271	39	32	limited	limited	ADJ
admet-1271	39	33	potential	potential	NOUN
admet-1271	39	34	for	for	ADP
admet-1271	39	35	clinical	clinical	ADJ
admet-1271	39	36	differentiation	differentiation	NOUN
admet-1271	39	37	.	.	PUNCT
admet-1271	40	1	innovation	innovation	NOUN
admet-1271	40	2	in	in	ADP
admet-1271	40	3	traditional	traditional	ADJ
admet-1271	40	4	antibacterial	antibacterial	ADJ
admet-1271	40	5	agents	agent	NOUN
admet-1271	40	6	traditional	traditional	ADJ
admet-1271	40	7	antibacterial	antibacterial	ADJ
admet-1271	40	8	agents	agent	NOUN
admet-1271	40	9	are	be	AUX
admet-1271	40	10	defined	define	VERB
admet-1271	40	11	as	as	ADP
admet-1271	40	12	small	small	ADJ
admet-1271	40	13	-	-	PUNCT
admet-1271	40	14	molecule	molecule	NOUN
admet-1271	40	15	agents	agent	NOUN
admet-1271	40	16	that	that	PRON
admet-1271	40	17	directly	directly	ADV
admet-1271	40	18	target	target	VERB
admet-1271	40	19	bacteria	bacteria	NOUN
admet-1271	40	20	to	to	PART
admet-1271	40	21	either	either	CCONJ
admet-1271	40	22	halt	halt	VERB
admet-1271	40	23	their	their	PRON
admet-1271	40	24	growth	growth	NOUN
admet-1271	40	25	(	(	PUNCT
admet-1271	40	26	bacteriostatic	bacteriostatic	ADJ
admet-1271	40	27	effect	effect	NOUN
admet-1271	40	28	)	)	PUNCT
admet-1271	40	29	or	or	CCONJ
admet-1271	40	30	to	to	PART
admet-1271	40	31	kill	kill	VERB
admet-1271	40	32	them	they	PRON
admet-1271	40	33	(	(	PUNCT
admet-1271	40	34	bactericidal	bactericidal	ADJ
admet-1271	40	35	effect	effect	NOUN
admet-1271	40	36	)	)	PUNCT
admet-1271	41	1	[	[	X
admet-1271	41	2	11	11	NUM
admet-1271	41	3	]	]	PUNCT
admet-1271	41	4	.	.	PUNCT
admet-1271	42	1	the	the	DET
admet-1271	42	2	current	current	ADJ
admet-1271	42	3	clinical	clinical	ADJ
admet-1271	42	4	antibacterial	antibacterial	ADJ
admet-1271	42	5	pipeline	pipeline	NOUN
admet-1271	42	6	counts	count	VERB
admet-1271	42	7	approximately	approximately	ADV
admet-1271	42	8	78	78	NUM
admet-1271	42	9	antibacterial	antibacterial	ADJ
admet-1271	42	10	agents	agent	NOUN
admet-1271	42	11	containing	contain	VERB
admet-1271	42	12	either	either	CCONJ
admet-1271	42	13	new	new	ADJ
admet-1271	42	14	therapeutic	therapeutic	ADJ
admet-1271	42	15	entity	entity	NOUN
admet-1271	42	16	or	or	CCONJ
admet-1271	42	17	combinations	combination	NOUN
admet-1271	42	18	of	of	ADP
admet-1271	42	19	existing	exist	VERB
admet-1271	42	20	molecules	molecule	NOUN
admet-1271	42	21	with	with	ADP
admet-1271	42	22	at	at	ADV
admet-1271	42	23	least	least	ADV
admet-1271	42	24	one	one	NUM
admet-1271	42	25	new	new	ADJ
admet-1271	42	26	therapeutic	therapeutic	ADJ
admet-1271	42	27	entity	entity	NOUN
admet-1271	42	28	.	.	PUNCT
admet-1271	43	1	among	among	ADP
admet-1271	43	2	the	the	DET
admet-1271	43	3	78	78	NUM
admet-1271	43	4	products	product	NOUN
admet-1271	43	5	,	,	PUNCT
admet-1271	43	6	45	45	NUM
admet-1271	43	7	are	be	AUX
admet-1271	43	8	traditional	traditional	ADJ
admet-1271	43	9	antibacterial	antibacterial	ADJ
admet-1271	43	10	agents	agent	NOUN
admet-1271	43	11	and	and	CCONJ
admet-1271	43	12	33	33	NUM
admet-1271	43	13	are	be	AUX
admet-1271	43	14	nontraditional	nontraditional	ADJ
admet-1271	43	15	agents	agent	NOUN
admet-1271	43	16	.	.	PUNCT
admet-1271	44	1	of	of	ADP
admet-1271	44	2	the	the	DET
admet-1271	44	3	45	45	NUM
admet-1271	44	4	traditional	traditional	ADJ
admet-1271	44	5	antibiotics	antibiotic	NOUN
admet-1271	44	6	,	,	PUNCT
admet-1271	44	7	27	27	NUM
admet-1271	44	8	(	(	PUNCT
admet-1271	44	9	60	60	NUM
admet-1271	44	10	admet	admet	X
admet-1271	44	11	&	&	CCONJ
admet-1271	44	12	dmpk	dmpk	PROPN
admet-1271	44	13	10(2	10(2	NUM
admet-1271	44	14	)	)	PUNCT
admet-1271	44	15	(	(	PUNCT
admet-1271	44	16	2022	2022	NUM
admet-1271	44	17	)	)	PUNCT
admet-1271	44	18	147	147	NUM
admet-1271	44	19	-	-	SYM
admet-1271	44	20	151	151	NUM
admet-1271	44	21	challenges	challenge	NOUN
admet-1271	44	22	in	in	ADP
admet-1271	44	23	antibacterial	antibacterial	ADJ
admet-1271	44	24	drug	drug	NOUN
admet-1271	44	25	development	development	NOUN
admet-1271	44	26	doi	doi	PROPN
admet-1271	44	27	:	:	PUNCT
admet-1271	44	28	http://dx.doi.org/10.5599/admet.1271	http://dx.doi.org/10.5599/admet.1271	X
admet-1271	44	29	149	149	NUM
admet-1271	44	30	%	%	NOUN
admet-1271	44	31	)	)	PUNCT
admet-1271	44	32	are	be	AUX
admet-1271	44	33	reported	report	VERB
admet-1271	44	34	to	to	PART
admet-1271	44	35	be	be	AUX
admet-1271	44	36	active	active	ADJ
admet-1271	44	37	against	against	ADP
admet-1271	44	38	the	the	DET
admet-1271	44	39	who	who	PRON
admet-1271	44	40	bacterial	bacterial	ADJ
admet-1271	44	41	priority	priority	NOUN
admet-1271	44	42	pathogens	pathogen	NOUN
admet-1271	44	43	,	,	PUNCT
admet-1271	44	44	13	13	NUM
admet-1271	44	45	(	(	PUNCT
admet-1271	44	46	31.1	31.1	NUM
admet-1271	44	47	%	%	NOUN
admet-1271	44	48	)	)	PUNCT
admet-1271	44	49	against	against	ADP
admet-1271	44	50	mycobacterium	mycobacterium	NOUN
admet-1271	44	51	tuberculosis	tuberculosis	NOUN
admet-1271	44	52	(	(	PUNCT
admet-1271	44	53	tb	tb	NOUN
admet-1271	44	54	)	)	PUNCT
admet-1271	44	55	and	and	CCONJ
admet-1271	44	56	five	five	NUM
admet-1271	44	57	(	(	PUNCT
admet-1271	44	58	11.1	11.1	NUM
admet-1271	44	59	%	%	NOUN
admet-1271	44	60	)	)	PUNCT
admet-1271	44	61	against	against	ADP
admet-1271	44	62	clostridium	clostridium	NOUN
admet-1271	44	63	difficile	difficile	NOUN
admet-1271	44	64	[	[	X
admet-1271	44	65	5	5	NUM
admet-1271	44	66	]	]	PUNCT
admet-1271	44	67	.	.	PUNCT
admet-1271	45	1	innovation	innovation	NOUN
admet-1271	45	2	is	be	AUX
admet-1271	45	3	a	a	DET
admet-1271	45	4	key	key	ADJ
admet-1271	45	5	aspect	aspect	NOUN
admet-1271	45	6	evaluated	evaluate	VERB
admet-1271	45	7	when	when	SCONJ
admet-1271	45	8	reviewing	review	VERB
admet-1271	45	9	antibacterial	antibacterial	ADJ
admet-1271	45	10	agents	agent	NOUN
admet-1271	45	11	in	in	ADP
admet-1271	45	12	clinical	clinical	ADJ
admet-1271	45	13	development	development	NOUN
admet-1271	45	14	.	.	PUNCT
admet-1271	46	1	there	there	PRON
admet-1271	46	2	is	be	VERB
admet-1271	46	3	a	a	DET
admet-1271	46	4	lack	lack	NOUN
admet-1271	46	5	of	of	ADP
admet-1271	46	6	consensus	consensus	NOUN
admet-1271	46	7	on	on	ADP
admet-1271	46	8	what	what	PRON
admet-1271	46	9	qualifies	qualify	VERB
admet-1271	46	10	as	as	ADP
admet-1271	46	11	innovative	innovative	ADJ
admet-1271	46	12	antibacterial	antibacterial	ADJ
admet-1271	46	13	agent	agent	NOUN
admet-1271	46	14	.	.	PUNCT
admet-1271	47	1	who	who	PRON
admet-1271	47	2	looks	look	VERB
admet-1271	47	3	for	for	ADP
admet-1271	47	4	evidence	evidence	NOUN
admet-1271	47	5	of	of	ADP
admet-1271	47	6	innovation	innovation	NOUN
admet-1271	47	7	in	in	ADP
admet-1271	47	8	:	:	PUNCT
admet-1271	47	9	the	the	DET
admet-1271	47	10	proposed	propose	VERB
admet-1271	47	11	class	class	NOUN
admet-1271	47	12	;	;	PUNCT
admet-1271	47	13	the	the	DET
admet-1271	47	14	mechanism	mechanism	NOUN
admet-1271	47	15	of	of	ADP
admet-1271	47	16	action	action	NOUN
admet-1271	47	17	;	;	PUNCT
admet-1271	47	18	the	the	DET
admet-1271	47	19	molecular	molecular	ADJ
admet-1271	47	20	target	target	NOUN
admet-1271	47	21	;	;	PUNCT
admet-1271	47	22	and	and	CCONJ
admet-1271	47	23	the	the	DET
admet-1271	47	24	absence	absence	NOUN
admet-1271	47	25	of	of	ADP
admet-1271	47	26	crossresistance	crossresistance	NOUN
admet-1271	47	27	.	.	PUNCT
admet-1271	48	1	[	[	X
admet-1271	48	2	5	5	NUM
admet-1271	48	3	]	]	PUNCT
admet-1271	48	4	.	.	PUNCT
admet-1271	49	1	considering	consider	VERB
admet-1271	49	2	the	the	DET
admet-1271	49	3	chemical	chemical	NOUN
admet-1271	49	4	class	class	NOUN
admet-1271	49	5	and	and	CCONJ
admet-1271	49	6	the	the	DET
admet-1271	49	7	molecular	molecular	ADJ
admet-1271	49	8	target	target	NOUN
admet-1271	49	9	,	,	PUNCT
admet-1271	49	10	among	among	ADP
admet-1271	49	11	the	the	DET
admet-1271	49	12	27	27	NUM
admet-1271	49	13	agents	agent	NOUN
admet-1271	49	14	identified	identify	VERB
admet-1271	49	15	against	against	ADP
admet-1271	49	16	the	the	DET
admet-1271	49	17	who	who	PRON
admet-1271	49	18	critical	critical	ADJ
admet-1271	49	19	priority	priority	NOUN
admet-1271	49	20	pathogens	pathogen	NOUN
admet-1271	49	21	,	,	PUNCT
admet-1271	49	22	most	most	ADJ
admet-1271	49	23	of	of	ADP
admet-1271	49	24	the	the	DET
admet-1271	49	25	antimicrobial	antimicrobial	ADJ
admet-1271	49	26	agents	agent	NOUN
admet-1271	49	27	in	in	ADP
admet-1271	49	28	the	the	DET
admet-1271	49	29	clinical	clinical	ADJ
admet-1271	49	30	pipeline	pipeline	NOUN
admet-1271	49	31	are	be	AUX
admet-1271	49	32	derivatives	derivative	NOUN
admet-1271	49	33	of	of	ADP
admet-1271	49	34	existing	exist	VERB
admet-1271	49	35	classes	class	NOUN
admet-1271	49	36	and	and	CCONJ
admet-1271	49	37	β	β	NOUN
admet-1271	49	38	-	-	NOUN
admet-1271	49	39	lactams	lactam	NOUN
admet-1271	49	40	-	-	PUNCT
admet-1271	49	41	β	β	NOUN
admet-1271	49	42	-	-	PUNCT
admet-1271	49	43	lactamase	lactamase	ADJ
admet-1271	49	44	inhibitors	inhibitor	NOUN
admet-1271	49	45	(	(	PUNCT
admet-1271	49	46	blis	blis	PROPN
admet-1271	49	47	)	)	PUNCT
admet-1271	49	48	accounts	account	VERB
admet-1271	49	49	for	for	ADP
admet-1271	49	50	over	over	ADP
admet-1271	49	51	40	40	NUM
admet-1271	49	52	%	%	NOUN
admet-1271	49	53	(	(	PUNCT
admet-1271	49	54	12/27	12/27	NUM
admet-1271	49	55	)	)	PUNCT
admet-1271	49	56	of	of	ADP
admet-1271	49	57	these	these	DET
admet-1271	49	58	agents	agent	NOUN
admet-1271	49	59	.	.	PUNCT
admet-1271	50	1	most	most	ADJ
admet-1271	50	2	of	of	ADP
admet-1271	50	3	these	these	DET
admet-1271	50	4	combinations	combination	NOUN
admet-1271	50	5	are	be	AUX
admet-1271	50	6	active	active	ADJ
admet-1271	50	7	against	against	ADP
admet-1271	50	8	class	class	NOUN
admet-1271	50	9	a	a	NOUN
admet-1271	50	10	,	,	PUNCT
admet-1271	50	11	and	and	CCONJ
admet-1271	50	12	c	c	AUX
admet-1271	50	13	and	and	CCONJ
admet-1271	50	14	some	some	PRON
admet-1271	50	15	are	be	AUX
admet-1271	50	16	active	active	ADJ
admet-1271	50	17	against	against	ADP
admet-1271	50	18	class	class	NOUN
admet-1271	50	19	d	d	NOUN
admet-1271	50	20	enzymes	enzyme	NOUN
admet-1271	50	21	.	.	PUNCT
admet-1271	51	1	very	very	ADV
admet-1271	51	2	few	few	ADJ
admet-1271	51	3	are	be	AUX
admet-1271	51	4	reported	report	VERB
admet-1271	51	5	to	to	PART
admet-1271	51	6	target	target	VERB
admet-1271	51	7	class	class	NOUN
admet-1271	51	8	b	b	NOUN
admet-1271	51	9	enzymes	enzyme	NOUN
admet-1271	51	10	(	(	PUNCT
admet-1271	51	11	mbls	mbls	NOUN
admet-1271	51	12	)	)	PUNCT
admet-1271	51	13	.	.	PUNCT
admet-1271	52	1	both	both	PRON
admet-1271	52	2	pseudomonas	pseudomona	VERB
admet-1271	52	3	aeruginosa	aeruginosa	NOUN
admet-1271	52	4	and	and	CCONJ
admet-1271	52	5	,	,	PUNCT
admet-1271	52	6	to	to	ADP
admet-1271	52	7	a	a	DET
admet-1271	52	8	certain	certain	ADJ
admet-1271	52	9	extent	extent	NOUN
admet-1271	52	10	,	,	PUNCT
admet-1271	52	11	acinetobacter	acinetobacter	ADV
admet-1271	52	12	baumannii	baumannii	PROPN
admet-1271	52	13	,	,	PUNCT
admet-1271	52	14	have	have	AUX
admet-1271	52	15	developed	develop	VERB
admet-1271	52	16	resistance	resistance	NOUN
admet-1271	52	17	mechanisms	mechanism	NOUN
admet-1271	52	18	beyond	beyond	ADP
admet-1271	52	19	the	the	DET
admet-1271	52	20	production	production	NOUN
admet-1271	52	21	of	of	ADP
admet-1271	52	22	βlactamases	βlactamase	NOUN
admet-1271	52	23	,	,	PUNCT
admet-1271	52	24	including	include	VERB
admet-1271	52	25	decreased	decrease	VERB
admet-1271	52	26	permeability	permeability	NOUN
admet-1271	52	27	of	of	ADP
admet-1271	52	28	the	the	DET
admet-1271	52	29	outer	outer	ADJ
admet-1271	52	30	membrane	membrane	NOUN
admet-1271	52	31	and	and	CCONJ
admet-1271	52	32	upregulation	upregulation	NOUN
admet-1271	52	33	of	of	ADP
admet-1271	52	34	efflux	efflux	NOUN
admet-1271	52	35	pumps	pump	NOUN
admet-1271	52	36	and	and	CCONJ
admet-1271	52	37	modified	modify	VERB
admet-1271	52	38	penicillin	penicillin	NOUN
admet-1271	52	39	-	-	PUNCT
admet-1271	52	40	binding	bind	VERB
admet-1271	52	41	protein	protein	NOUN
admet-1271	52	42	(	(	PUNCT
admet-1271	52	43	pbp	pbp	NOUN
admet-1271	52	44	)	)	PUNCT
admet-1271	52	45	.	.	PUNCT
admet-1271	53	1	this	this	PRON
admet-1271	53	2	may	may	AUX
admet-1271	53	3	explain	explain	VERB
admet-1271	53	4	the	the	DET
admet-1271	53	5	copious	copious	ADJ
admet-1271	53	6	β	β	NOUN
admet-1271	53	7	-	-	PUNCT
admet-1271	53	8	lactams	lactam	NOUN
admet-1271	53	9	-	-	PUNCT
admet-1271	53	10	blis	blis	PROPN
admet-1271	53	11	combinations	combination	NOUN
admet-1271	53	12	approach	approach	NOUN
admet-1271	53	13	found	find	VERB
admet-1271	53	14	in	in	ADP
admet-1271	53	15	the	the	DET
admet-1271	53	16	pipeline	pipeline	NOUN
admet-1271	53	17	,	,	PUNCT
admet-1271	53	18	which	which	PRON
admet-1271	53	19	attempts	attempt	VERB
admet-1271	53	20	to	to	PART
admet-1271	53	21	overcome	overcome	VERB
admet-1271	53	22	these	these	DET
admet-1271	53	23	resistance	resistance	NOUN
admet-1271	53	24	mechanisms	mechanism	NOUN
admet-1271	53	25	challenges	challenge	NOUN
admet-1271	53	26	.	.	PUNCT
admet-1271	54	1	however	however	ADV
admet-1271	54	2	,	,	PUNCT
admet-1271	54	3	this	this	DET
admet-1271	54	4	approach	approach	NOUN
admet-1271	54	5	also	also	ADV
admet-1271	54	6	reflects	reflect	VERB
admet-1271	54	7	a	a	DET
admet-1271	54	8	lack	lack	NOUN
admet-1271	54	9	of	of	ADP
admet-1271	54	10	innovation	innovation	NOUN
admet-1271	54	11	in	in	ADP
admet-1271	54	12	terms	term	NOUN
admet-1271	54	13	of	of	ADP
admet-1271	54	14	new	new	ADJ
admet-1271	54	15	chemical	chemical	NOUN
admet-1271	54	16	classes	class	NOUN
admet-1271	54	17	and	and	CCONJ
admet-1271	54	18	may	may	AUX
admet-1271	54	19	result	result	VERB
admet-1271	54	20	in	in	ADP
admet-1271	54	21	many	many	ADJ
admet-1271	54	22	“	"	PUNCT
admet-1271	54	23	me	i	PRON
admet-1271	54	24	too	too	ADV
admet-1271	54	25	”	"	PUNCT
admet-1271	54	26	agents	agent	NOUN
admet-1271	54	27	with	with	ADP
admet-1271	54	28	limited	limited	ADJ
admet-1271	54	29	potential	potential	NOUN
admet-1271	54	30	for	for	ADP
admet-1271	54	31	clinical	clinical	ADJ
admet-1271	54	32	differentiation	differentiation	NOUN
admet-1271	54	33	.	.	PUNCT
admet-1271	55	1	in	in	ADP
admet-1271	55	2	fact	fact	NOUN
admet-1271	55	3	,	,	PUNCT
admet-1271	55	4	examining	examine	VERB
admet-1271	55	5	all	all	DET
admet-1271	55	6	the	the	DET
admet-1271	55	7	27	27	NUM
admet-1271	55	8	traditional	traditional	ADJ
admet-1271	55	9	agents	agent	NOUN
admet-1271	55	10	under	under	ADP
admet-1271	55	11	development	development	NOUN
admet-1271	55	12	against	against	ADP
admet-1271	55	13	who	who	PRON
admet-1271	55	14	bacterial	bacterial	ADJ
admet-1271	55	15	priority	priority	NOUN
admet-1271	55	16	pathogens	pathogen	NOUN
admet-1271	55	17	,	,	PUNCT
admet-1271	55	18	only	only	ADV
admet-1271	55	19	a	a	DET
admet-1271	55	20	few	few	ADJ
admet-1271	55	21	compounds	compound	NOUN
admet-1271	55	22	in	in	ADP
admet-1271	55	23	clinical	clinical	ADJ
admet-1271	55	24	development	development	NOUN
admet-1271	55	25	satisfy	satisfy	NOUN
admet-1271	55	26	at	at	ADV
admet-1271	55	27	least	least	ADJ
admet-1271	55	28	one	one	NUM
admet-1271	55	29	of	of	ADP
admet-1271	55	30	the	the	DET
admet-1271	55	31	innovation	innovation	NOUN
admet-1271	55	32	criteria	criterion	NOUN
admet-1271	55	33	described	describe	VERB
admet-1271	55	34	and	and	CCONJ
admet-1271	55	35	address	address	NOUN
admet-1271	55	36	at	at	ADP
admet-1271	55	37	the	the	DET
admet-1271	55	38	same	same	ADJ
admet-1271	55	39	time	time	NOUN
admet-1271	55	40	critical	critical	ADJ
admet-1271	55	41	gram	gram	NOUN
admet-1271	55	42	-	-	PUNCT
admet-1271	55	43	negative	negative	ADJ
admet-1271	55	44	bacteria	bacteria	NOUN
admet-1271	55	45	(	(	PUNCT
admet-1271	55	46	crab	crab	NOUN
admet-1271	55	47	,	,	PUNCT
admet-1271	55	48	crpa	crpa	NOUN
admet-1271	55	49	or	or	CCONJ
admet-1271	55	50	cre	cre	PROPN
admet-1271	55	51	)	)	PUNCT
admet-1271	55	52	.	.	PUNCT
admet-1271	56	1	the	the	DET
admet-1271	56	2	anti	anti	ADJ
admet-1271	56	3	-	-	ADJ
admet-1271	56	4	tb	tb	ADJ
admet-1271	56	5	clinical	clinical	ADJ
admet-1271	56	6	antibacterial	antibacterial	ADJ
admet-1271	56	7	pipeline	pipeline	NOUN
admet-1271	56	8	,	,	PUNCT
admet-1271	56	9	on	on	ADP
admet-1271	56	10	the	the	DET
admet-1271	56	11	other	other	ADJ
admet-1271	56	12	hand	hand	NOUN
admet-1271	56	13	,	,	PUNCT
admet-1271	56	14	looks	look	VERB
admet-1271	56	15	more	more	ADV
admet-1271	56	16	innovative	innovative	ADJ
admet-1271	56	17	,	,	PUNCT
admet-1271	56	18	with	with	ADP
admet-1271	56	19	seven	seven	NUM
admet-1271	56	20	(	(	PUNCT
admet-1271	56	21	53	53	NUM
admet-1271	56	22	%	%	NOUN
admet-1271	56	23	)	)	PUNCT
admet-1271	56	24	agents	agent	NOUN
admet-1271	56	25	showing	show	VERB
admet-1271	56	26	new	new	ADJ
admet-1271	56	27	chemical	chemical	NOUN
admet-1271	56	28	structures	structure	NOUN
admet-1271	56	29	.	.	PUNCT
admet-1271	57	1	it	it	PRON
admet-1271	57	2	is	be	AUX
admet-1271	57	3	important	important	ADJ
admet-1271	57	4	to	to	PART
admet-1271	57	5	point	point	VERB
admet-1271	57	6	out	out	ADP
admet-1271	57	7	here	here	ADV
admet-1271	57	8	that	that	SCONJ
admet-1271	57	9	for	for	ADP
admet-1271	57	10	any	any	DET
admet-1271	57	11	given	give	VERB
admet-1271	57	12	agent	agent	NOUN
admet-1271	57	13	in	in	ADP
admet-1271	57	14	development	development	NOUN
admet-1271	57	15	,	,	PUNCT
admet-1271	57	16	meeting	meet	VERB
admet-1271	57	17	one	one	NUM
admet-1271	57	18	or	or	CCONJ
admet-1271	57	19	more	more	ADJ
admet-1271	57	20	of	of	ADP
admet-1271	57	21	the	the	DET
admet-1271	57	22	innovation	innovation	NOUN
admet-1271	57	23	criteria	criterion	NOUN
admet-1271	57	24	described	describe	VERB
admet-1271	57	25	must	must	AUX
admet-1271	57	26	be	be	AUX
admet-1271	57	27	interpreted	interpret	VERB
admet-1271	57	28	in	in	ADP
admet-1271	57	29	the	the	DET
admet-1271	57	30	context	context	NOUN
admet-1271	57	31	of	of	ADP
admet-1271	57	32	clinical	clinical	ADJ
admet-1271	57	33	and	and	CCONJ
admet-1271	57	34	public	public	ADJ
admet-1271	57	35	health	health	NOUN
admet-1271	57	36	unmet	unmet	NOUN
admet-1271	57	37	needs	need	VERB
admet-1271	57	38	.	.	PUNCT
admet-1271	58	1	nontraditional	nontraditional	ADJ
admet-1271	58	2	agents	agent	NOUN
admet-1271	58	3	,	,	PUNCT
admet-1271	58	4	new	new	ADJ
admet-1271	58	5	approaches	approach	NOUN
admet-1271	58	6	,	,	PUNCT
admet-1271	58	7	same	same	ADJ
admet-1271	58	8	developmental	developmental	ADJ
admet-1271	58	9	pathway	pathway	NOUN
admet-1271	58	10	“	"	PUNCT
admet-1271	58	11	nontraditional	nontraditional	ADJ
admet-1271	58	12	antimicrobials	antimicrobial	NOUN
admet-1271	58	13	”	"	PUNCT
admet-1271	58	14	refers	refer	VERB
admet-1271	58	15	to	to	ADP
admet-1271	58	16	therapies	therapy	NOUN
admet-1271	58	17	that	that	PRON
admet-1271	58	18	are	be	AUX
admet-1271	58	19	not	not	PART
admet-1271	58	20	small	small	ADJ
admet-1271	58	21	molecules	molecule	NOUN
admet-1271	58	22	and/or	and/or	CCONJ
admet-1271	58	23	aim	aim	VERB
admet-1271	58	24	at	at	ADP
admet-1271	58	25	a	a	DET
admet-1271	58	26	nontraditional	nontraditional	ADJ
admet-1271	58	27	target	target	NOUN
admet-1271	58	28	and	and	CCONJ
admet-1271	58	29	include	include	VERB
admet-1271	58	30	a	a	DET
admet-1271	58	31	broad	broad	ADJ
admet-1271	58	32	range	range	NOUN
admet-1271	58	33	of	of	ADP
admet-1271	58	34	agents	agent	NOUN
admet-1271	58	35	[	[	X
admet-1271	58	36	12	12	NUM
admet-1271	58	37	]	]	PUNCT
admet-1271	58	38	.	.	PUNCT
admet-1271	59	1	since	since	SCONJ
admet-1271	59	2	2019	2019	NUM
admet-1271	59	3	,	,	PUNCT
admet-1271	59	4	the	the	PRON
admet-1271	59	5	who	who	PRON
admet-1271	59	6	antibacterial	antibacterial	ADJ
admet-1271	59	7	pipeline	pipeline	NOUN
admet-1271	59	8	analysis	analysis	NOUN
admet-1271	59	9	has	have	AUX
admet-1271	59	10	examined	examine	VERB
admet-1271	59	11	these	these	DET
admet-1271	59	12	new	new	ADJ
admet-1271	59	13	strategies	strategy	NOUN
admet-1271	59	14	as	as	ADP
admet-1271	59	15	complementary	complementary	ADJ
admet-1271	59	16	and	and	CCONJ
admet-1271	59	17	synergistic	synergistic	ADJ
admet-1271	59	18	,	,	PUNCT
admet-1271	59	19	or	or	CCONJ
admet-1271	59	20	even	even	ADV
admet-1271	59	21	future	future	ADJ
admet-1271	59	22	alternative	alternative	NOUN
admet-1271	59	23	to	to	ADP
admet-1271	59	24	traditional	traditional	ADJ
admet-1271	59	25	antibacterial	antibacterial	ADJ
admet-1271	59	26	agents	agent	NOUN
admet-1271	59	27	(	(	PUNCT
admet-1271	59	28	i.e.	i.e.	X
admet-1271	59	29	,	,	PUNCT
admet-1271	59	30	small	small	ADJ
admet-1271	59	31	molecules	molecule	NOUN
admet-1271	59	32	)	)	PUNCT
admet-1271	60	1	[	[	X
admet-1271	60	2	13	13	NUM
admet-1271	60	3	]	]	PUNCT
admet-1271	60	4	.	.	PUNCT
admet-1271	61	1	among	among	ADP
admet-1271	61	2	the	the	DET
admet-1271	61	3	78	78	NUM
admet-1271	61	4	products	product	NOUN
admet-1271	61	5	identified	identify	VERB
admet-1271	61	6	in	in	ADP
admet-1271	61	7	the	the	DET
admet-1271	61	8	clinical	clinical	ADJ
admet-1271	61	9	pipeline	pipeline	NOUN
admet-1271	61	10	,	,	PUNCT
admet-1271	61	11	34	34	NUM
admet-1271	61	12	are	be	AUX
admet-1271	61	13	nontraditional	nontraditional	ADJ
admet-1271	61	14	agents	agent	NOUN
admet-1271	61	15	in	in	ADP
admet-1271	61	16	a	a	DET
admet-1271	61	17	different	different	ADJ
admet-1271	61	18	stage	stage	NOUN
admet-1271	61	19	of	of	ADP
admet-1271	61	20	development	development	NOUN
admet-1271	61	21	:	:	PUNCT
admet-1271	61	22	two	two	NUM
admet-1271	61	23	are	be	AUX
admet-1271	61	24	in	in	ADP
admet-1271	61	25	the	the	DET
admet-1271	61	26	marketing	marketing	NOUN
admet-1271	61	27	,	,	PUNCT
admet-1271	61	28	authorization	authorization	NOUN
admet-1271	61	29	,	,	PUNCT
admet-1271	61	30	application	application	NOUN
admet-1271	61	31	/	/	SYM
admet-1271	61	32	new	new	ADJ
admet-1271	61	33	drug	drug	NOUN
admet-1271	61	34	application	application	NOUN
admet-1271	61	35	(	(	PUNCT
admet-1271	61	36	maa	maa	PROPN
admet-1271	61	37	/	/	SYM
admet-1271	61	38	nda	nda	PROPN
admet-1271	61	39	)	)	PUNCT
admet-1271	61	40	stage	stage	NOUN
admet-1271	61	41	,	,	PUNCT
admet-1271	61	42	five	five	NUM
admet-1271	61	43	products	product	NOUN
admet-1271	61	44	in	in	ADP
admet-1271	61	45	phase	phase	NOUN
admet-1271	61	46	3	3	NUM
admet-1271	61	47	,	,	PUNCT
admet-1271	61	48	eleven	eleven	NUM
admet-1271	61	49	in	in	ADP
admet-1271	61	50	phase	phase	NOUN
admet-1271	61	51	2	2	NUM
admet-1271	61	52	,	,	PUNCT
admet-1271	61	53	and	and	CCONJ
admet-1271	61	54	five	five	NUM
admet-1271	61	55	in	in	ADP
admet-1271	61	56	phase	phase	NOUN
admet-1271	61	57	1/2	1/2	NUM
admet-1271	61	58	.	.	PUNCT
admet-1271	62	1	nontraditional	nontraditional	ADJ
admet-1271	62	2	agents	agent	NOUN
admet-1271	62	3	encompass	encompass	VERB
admet-1271	62	4	different	different	ADJ
admet-1271	62	5	categories	category	NOUN
admet-1271	62	6	from	from	ADP
admet-1271	62	7	phage	phage	NOUN
admet-1271	62	8	-	-	PUNCT
admet-1271	62	9	based	base	VERB
admet-1271	62	10	therapies	therapy	NOUN
admet-1271	62	11	to	to	ADP
admet-1271	62	12	monoclonal	monoclonal	NOUN
admet-1271	62	13	antibodies	antibody	NOUN
admet-1271	62	14	,	,	PUNCT
admet-1271	62	15	antimicrobial	antimicrobial	ADJ
admet-1271	62	16	peptides	peptide	NOUN
admet-1271	62	17	and	and	CCONJ
admet-1271	62	18	antibacterial	antibacterial	ADJ
admet-1271	62	19	enhancers	enhancer	NOUN
admet-1271	62	20	.	.	PUNCT
admet-1271	63	1	due	due	ADP
admet-1271	63	2	to	to	ADP
admet-1271	63	3	the	the	DET
admet-1271	63	4	wide	wide	ADJ
admet-1271	63	5	range	range	NOUN
admet-1271	63	6	of	of	ADP
admet-1271	63	7	approaches	approach	NOUN
admet-1271	63	8	pursued	pursue	VERB
admet-1271	63	9	in	in	ADP
admet-1271	63	10	the	the	DET
admet-1271	63	11	nontraditional	nontraditional	ADJ
admet-1271	63	12	pipeline	pipeline	NOUN
admet-1271	63	13	,	,	PUNCT
admet-1271	63	14	these	these	DET
admet-1271	63	15	agents	agent	NOUN
admet-1271	63	16	hold	hold	VERB
admet-1271	63	17	a	a	DET
admet-1271	63	18	great	great	ADJ
admet-1271	63	19	potential	potential	NOUN
admet-1271	63	20	to	to	PART
admet-1271	63	21	curb	curb	VERB
admet-1271	63	22	amr	amr	NOUN
admet-1271	63	23	.	.	PUNCT
admet-1271	64	1	although	although	SCONJ
admet-1271	64	2	very	very	ADV
admet-1271	64	3	distinct	distinct	ADJ
admet-1271	64	4	from	from	ADP
admet-1271	64	5	each	each	DET
admet-1271	64	6	other	other	ADJ
admet-1271	64	7	in	in	ADP
admet-1271	64	8	their	their	PRON
admet-1271	64	9	nature	nature	NOUN
admet-1271	64	10	,	,	PUNCT
admet-1271	64	11	for	for	ADP
admet-1271	64	12	the	the	DET
admet-1271	64	13	most	most	ADJ
admet-1271	64	14	part	part	NOUN
admet-1271	64	15	,	,	PUNCT
admet-1271	64	16	traditional	traditional	ADJ
admet-1271	64	17	and	and	CCONJ
admet-1271	64	18	nontraditional	nontraditional	ADJ
admet-1271	64	19	agents	agent	NOUN
admet-1271	64	20	should	should	AUX
admet-1271	64	21	be	be	AUX
admet-1271	64	22	considered	consider	VERB
admet-1271	64	23	comparable	comparable	ADJ
admet-1271	64	24	when	when	SCONJ
admet-1271	64	25	it	it	PRON
admet-1271	64	26	comes	come	VERB
admet-1271	64	27	to	to	ADP
admet-1271	64	28	the	the	DET
admet-1271	64	29	need	need	NOUN
admet-1271	64	30	to	to	PART
admet-1271	64	31	adhere	adhere	VERB
admet-1271	64	32	to	to	ADP
admet-1271	64	33	predictable	predictable	ADJ
admet-1271	64	34	regulatory	regulatory	ADJ
admet-1271	64	35	requirements	requirement	NOUN
admet-1271	64	36	for	for	ADP
admet-1271	64	37	their	their	PRON
admet-1271	64	38	development	development	NOUN
admet-1271	64	39	and	and	CCONJ
admet-1271	64	40	potentially	potentially	ADV
admet-1271	64	41	their	their	PRON
admet-1271	64	42	approvals	approval	NOUN
admet-1271	64	43	[	[	X
admet-1271	64	44	14	14	NUM
admet-1271	64	45	]	]	PUNCT
admet-1271	64	46	.	.	PUNCT
admet-1271	65	1	during	during	ADP
admet-1271	65	2	the	the	DET
admet-1271	65	3	who	who	PRON
admet-1271	65	4	technical	technical	ADJ
admet-1271	65	5	advisory	advisory	ADJ
admet-1271	65	6	group	group	NOUN
admet-1271	65	7	meeting	meeting	NOUN
admet-1271	65	8	on	on	ADP
admet-1271	65	9	antibacterial	antibacterial	ADJ
admet-1271	65	10	research	research	NOUN
admet-1271	65	11	and	and	CCONJ
admet-1271	65	12	development	development	NOUN
admet-1271	65	13	held	hold	VERB
admet-1271	65	14	on	on	ADP
admet-1271	65	15	29	29	NUM
admet-1271	65	16	and	and	CCONJ
admet-1271	65	17	30	30	NUM
admet-1271	65	18	november	november	NOUN
admet-1271	65	19	2021	2021	NUM
admet-1271	65	20	,	,	PUNCT
admet-1271	65	21	the	the	DET
admet-1271	65	22	scope	scope	NOUN
admet-1271	65	23	of	of	ADP
admet-1271	65	24	the	the	DET
admet-1271	65	25	nontraditional	nontraditional	ADJ
admet-1271	65	26	section	section	NOUN
admet-1271	65	27	was	be	AUX
admet-1271	65	28	discussed	discuss	VERB
admet-1271	65	29	,	,	PUNCT
admet-1271	65	30	and	and	CCONJ
admet-1271	65	31	it	it	PRON
admet-1271	65	32	was	be	AUX
admet-1271	65	33	decided	decide	VERB
admet-1271	65	34	that	that	SCONJ
admet-1271	65	35	bacteriophage	bacteriophage	NOUN
admet-1271	65	36	treatments	treatment	NOUN
admet-1271	65	37	will	will	AUX
admet-1271	65	38	be	be	AUX
admet-1271	65	39	included	include	VERB
admet-1271	65	40	in	in	ADP
admet-1271	65	41	the	the	PRON
admet-1271	65	42	who	who	PRON
admet-1271	65	43	pipeline	pipeline	VERB
admet-1271	65	44	analysis	analysis	NOUN
admet-1271	65	45	only	only	ADV
admet-1271	65	46	if	if	SCONJ
admet-1271	65	47	they	they	PRON
admet-1271	65	48	were	be	AUX
admet-1271	65	49	associated	associate	VERB
admet-1271	65	50	to	to	ADP
admet-1271	65	51	a	a	DET
admet-1271	65	52	http://dx.doi.org/10.5599/admet.1271	http://dx.doi.org/10.5599/admet.1271	X
admet-1271	65	53	gigante	gigante	PROPN
admet-1271	65	54	,	,	PUNCT
admet-1271	65	55	sati	sati	PROPN
admet-1271	65	56	and	and	CCONJ
admet-1271	65	57	beyer	beyer	PROPN
admet-1271	65	58	admet	admet	PROPN
admet-1271	65	59	&	&	CCONJ
admet-1271	65	60	dmpk	dmpk	PROPN
admet-1271	65	61	10(2	10(2	NUM
admet-1271	65	62	)	)	PUNCT
admet-1271	65	63	(	(	PUNCT
admet-1271	65	64	2022	2022	NUM
admet-1271	65	65	)	)	PUNCT
admet-1271	65	66	147	147	NUM
admet-1271	65	67	-	-	SYM
admet-1271	65	68	151	151	NUM
admet-1271	65	69	150	150	NUM
admet-1271	65	70	randomized	randomize	VERB
admet-1271	65	71	controlled	control	VERB
admet-1271	65	72	clinical	clinical	ADJ
admet-1271	65	73	trial	trial	NOUN
admet-1271	65	74	while	while	SCONJ
admet-1271	65	75	expanded	expand	VERB
admet-1271	65	76	access	access	NOUN
admet-1271	65	77	/	/	SYM
admet-1271	65	78	compassionate	compassionate	ADJ
admet-1271	65	79	use	use	NOUN
admet-1271	65	80	bacteriophage	bacteriophage	NOUN
admet-1271	65	81	programs	program	NOUN
admet-1271	65	82	wo	will	AUX
admet-1271	65	83	n’t	not	PART
admet-1271	65	84	be	be	AUX
admet-1271	65	85	listed	list	VERB
admet-1271	65	86	in	in	ADP
admet-1271	65	87	the	the	DET
admet-1271	65	88	pipeline	pipeline	NOUN
admet-1271	65	89	analysis	analysis	NOUN
admet-1271	65	90	.	.	PUNCT
admet-1271	66	1	in	in	ADP
admet-1271	66	2	addition	addition	NOUN
admet-1271	66	3	,	,	PUNCT
admet-1271	66	4	agents	agent	NOUN
admet-1271	66	5	against	against	ADP
admet-1271	66	6	biothreat	biothreat	NOUN
admet-1271	66	7	pathogens	pathogen	NOUN
admet-1271	66	8	will	will	AUX
admet-1271	66	9	likely	likely	ADV
admet-1271	66	10	be	be	AUX
admet-1271	66	11	considered	consider	VERB
admet-1271	66	12	in	in	ADP
admet-1271	66	13	the	the	DET
admet-1271	66	14	2023	2023	NUM
admet-1271	66	15	update	update	NOUN
admet-1271	66	16	of	of	ADP
admet-1271	66	17	the	the	DET
admet-1271	66	18	who	who	PRON
admet-1271	66	19	antibacterial	antibacterial	ADJ
admet-1271	66	20	pipeline	pipeline	NOUN
admet-1271	66	21	analysis	analysis	NOUN
admet-1271	66	22	and	and	CCONJ
admet-1271	66	23	will	will	AUX
admet-1271	66	24	also	also	ADV
admet-1271	66	25	be	be	AUX
admet-1271	66	26	evaluated	evaluate	VERB
admet-1271	66	27	in	in	ADP
admet-1271	66	28	the	the	DET
admet-1271	66	29	context	context	NOUN
admet-1271	66	30	of	of	ADP
admet-1271	66	31	the	the	DET
admet-1271	66	32	next	next	ADJ
admet-1271	66	33	update	update	NOUN
admet-1271	66	34	of	of	ADP
admet-1271	66	35	the	the	DET
admet-1271	66	36	who	who	PRON
admet-1271	66	37	bacterial	bacterial	ADJ
admet-1271	66	38	priority	priority	NOUN
admet-1271	66	39	pathogen	pathogen	NOUN
admet-1271	66	40	list	list	NOUN
admet-1271	66	41	(	(	PUNCT
admet-1271	66	42	bppl	bppl	NOUN
admet-1271	66	43	)	)	PUNCT
admet-1271	66	44	.	.	PUNCT
admet-1271	67	1	in	in	ADP
admet-1271	67	2	conclusion	conclusion	NOUN
admet-1271	67	3	,	,	PUNCT
admet-1271	67	4	in	in	ADP
admet-1271	67	5	the	the	DET
admet-1271	67	6	present	present	ADJ
admet-1271	67	7	scenario	scenario	NOUN
admet-1271	67	8	where	where	SCONJ
admet-1271	67	9	traditional	traditional	ADJ
admet-1271	67	10	products	product	NOUN
admet-1271	67	11	have	have	VERB
admet-1271	67	12	a	a	DET
admet-1271	67	13	limited	limited	ADJ
admet-1271	67	14	lifespan	lifespan	NOUN
admet-1271	67	15	before	before	SCONJ
admet-1271	67	16	resistance	resistance	NOUN
admet-1271	67	17	emerges	emerge	VERB
admet-1271	67	18	,	,	PUNCT
admet-1271	67	19	non	non	ADJ
admet-1271	67	20	-	-	ADJ
admet-1271	67	21	conventional	conventional	ADJ
admet-1271	67	22	approaches	approach	NOUN
admet-1271	67	23	offer	offer	VERB
admet-1271	67	24	opportunities	opportunity	NOUN
admet-1271	67	25	to	to	PART
admet-1271	67	26	preserve	preserve	VERB
admet-1271	67	27	new	new	ADJ
admet-1271	67	28	and	and	CCONJ
admet-1271	67	29	old	old	ADJ
admet-1271	67	30	traditional	traditional	ADJ
admet-1271	67	31	agents	agent	NOUN
admet-1271	67	32	,	,	PUNCT
admet-1271	67	33	and	and	CCONJ
admet-1271	67	34	to	to	PART
admet-1271	67	35	tackle	tackle	VERB
admet-1271	67	36	amr	amr	NOUN
admet-1271	67	37	from	from	ADP
admet-1271	67	38	different	different	ADJ
admet-1271	67	39	angles	angle	NOUN
admet-1271	67	40	.	.	PUNCT
admet-1271	68	1	preclinical	preclinical	ADJ
admet-1271	68	2	,	,	PUNCT
admet-1271	68	3	traveling	travel	VERB
admet-1271	68	4	the	the	DET
admet-1271	68	5	valley	valley	NOUN
admet-1271	68	6	of	of	ADP
admet-1271	68	7	death	death	NOUN
admet-1271	68	8	in	in	ADP
admet-1271	68	9	the	the	DET
admet-1271	68	10	preclinical	preclinical	ADJ
admet-1271	68	11	phase	phase	NOUN
admet-1271	68	12	,	,	PUNCT
admet-1271	68	13	there	there	PRON
admet-1271	68	14	is	be	VERB
admet-1271	68	15	a	a	DET
admet-1271	68	16	high	high	ADJ
admet-1271	68	17	turnover	turnover	NOUN
admet-1271	68	18	with	with	ADP
admet-1271	68	19	almost	almost	ADV
admet-1271	68	20	one	one	NUM
admet-1271	68	21	out	out	ADP
admet-1271	68	22	of	of	ADP
admet-1271	68	23	three	three	NUM
admet-1271	68	24	developers	developer	NOUN
admet-1271	68	25	lost	lose	VERB
admet-1271	68	26	every	every	DET
admet-1271	68	27	year	year	NOUN
admet-1271	68	28	.	.	PUNCT
admet-1271	69	1	half	half	NOUN
admet-1271	69	2	of	of	ADP
admet-1271	69	3	the	the	DET
admet-1271	69	4	products	product	NOUN
admet-1271	69	5	in	in	ADP
admet-1271	69	6	preclinical	preclinical	ADJ
admet-1271	69	7	development	development	NOUN
admet-1271	69	8	target	target	NOUN
admet-1271	69	9	a	a	DET
admet-1271	69	10	single	single	ADJ
admet-1271	69	11	species	specie	NOUN
admet-1271	69	12	,	,	PUNCT
admet-1271	69	13	with	with	ADP
admet-1271	69	14	56	56	NUM
admet-1271	69	15	%	%	NOUN
admet-1271	69	16	targeting	target	VERB
admet-1271	69	17	staphylococcus	staphylococcus	NOUN
admet-1271	69	18	aureus	aureus	NOUN
admet-1271	69	19	,	,	PUNCT
admet-1271	69	20	pseudomonas	pseudomona	VERB
admet-1271	69	21	aeruginosa	aeruginosa	NOUN
admet-1271	69	22	and	and	CCONJ
admet-1271	69	23	mycobacterium	mycobacterium	NOUN
admet-1271	69	24	tuberculosis	tuberculosis	NOUN
admet-1271	69	25	.	.	PUNCT
admet-1271	70	1	this	this	DET
admet-1271	70	2	trend	trend	NOUN
admet-1271	70	3	,	,	PUNCT
admet-1271	70	4	which	which	PRON
admet-1271	70	5	is	be	AUX
admet-1271	70	6	also	also	ADV
admet-1271	70	7	observed	observe	VERB
admet-1271	70	8	in	in	ADP
admet-1271	70	9	the	the	DET
admet-1271	70	10	nontraditional	nontraditional	ADJ
admet-1271	70	11	space	space	NOUN
admet-1271	70	12	,	,	PUNCT
admet-1271	70	13	requires	require	VERB
admet-1271	70	14	availability	availability	NOUN
admet-1271	70	15	of	of	ADP
admet-1271	70	16	diagnostics	diagnostic	NOUN
admet-1271	70	17	at	at	ADP
admet-1271	70	18	the	the	DET
admet-1271	70	19	point	point	NOUN
admet-1271	70	20	of	of	ADP
admet-1271	70	21	care	care	NOUN
admet-1271	70	22	for	for	ADP
admet-1271	70	23	optimal	optimal	ADJ
admet-1271	70	24	use	use	NOUN
admet-1271	70	25	,	,	PUNCT
admet-1271	70	26	often	often	ADV
admet-1271	70	27	unavailable	unavailable	ADJ
admet-1271	70	28	outside	outside	ADV
admet-1271	70	29	of	of	ADP
admet-1271	70	30	specialized	specialized	ADJ
admet-1271	70	31	healthcare	healthcare	NOUN
admet-1271	70	32	facilities	facility	NOUN
admet-1271	70	33	and	and	CCONJ
admet-1271	70	34	poses	pose	VERB
admet-1271	70	35	a	a	DET
admet-1271	70	36	challenge	challenge	NOUN
admet-1271	70	37	in	in	ADP
admet-1271	70	38	low	low	ADJ
admet-1271	70	39	-	-	PUNCT
admet-1271	70	40	resource	resource	NOUN
admet-1271	70	41	settings	setting	NOUN
admet-1271	70	42	.	.	PUNCT
admet-1271	71	1	overall	overall	ADV
admet-1271	71	2	,	,	PUNCT
admet-1271	71	3	our	our	PRON
admet-1271	71	4	analyses	analysis	NOUN
admet-1271	71	5	of	of	ADP
admet-1271	71	6	the	the	DET
admet-1271	71	7	preclinical	preclinical	ADJ
admet-1271	71	8	pipeline	pipeline	NOUN
admet-1271	71	9	indicate	indicate	VERB
admet-1271	71	10	a	a	DET
admet-1271	71	11	volatile	volatile	ADJ
admet-1271	71	12	landscape	landscape	NOUN
admet-1271	71	13	,	,	PUNCT
admet-1271	71	14	with	with	ADP
admet-1271	71	15	longer	long	ADJ
admet-1271	71	16	timeframes	timeframe	NOUN
admet-1271	71	17	and	and	CCONJ
admet-1271	71	18	challenging	challenging	ADJ
admet-1271	71	19	milestones	milestone	NOUN
admet-1271	71	20	to	to	PART
admet-1271	71	21	meet	meet	VERB
admet-1271	71	22	before	before	ADP
admet-1271	71	23	potentially	potentially	ADV
admet-1271	71	24	hitting	hit	VERB
admet-1271	71	25	the	the	DET
admet-1271	71	26	market	market	NOUN
admet-1271	71	27	.	.	PUNCT
admet-1271	72	1	thus	thus	ADV
admet-1271	72	2	,	,	PUNCT
admet-1271	72	3	public	public	ADJ
admet-1271	72	4	,	,	PUNCT
admet-1271	72	5	and	and	CCONJ
admet-1271	72	6	private	private	ADJ
admet-1271	72	7	incentives	incentive	NOUN
admet-1271	72	8	,	,	PUNCT
admet-1271	72	9	including	include	VERB
admet-1271	72	10	new	new	ADJ
admet-1271	72	11	funding	funding	NOUN
admet-1271	72	12	models	model	NOUN
admet-1271	72	13	becomes	become	VERB
admet-1271	72	14	crucial	crucial	ADJ
admet-1271	72	15	in	in	ADP
admet-1271	72	16	this	this	DET
admet-1271	72	17	space	space	NOUN
admet-1271	72	18	to	to	PART
admet-1271	72	19	continuously	continuously	ADV
admet-1271	72	20	feed	feed	VERB
admet-1271	72	21	the	the	DET
admet-1271	72	22	clinical	clinical	ADJ
admet-1271	72	23	development	development	NOUN
admet-1271	72	24	with	with	ADP
admet-1271	72	25	promising	promising	ADJ
admet-1271	72	26	,	,	PUNCT
admet-1271	72	27	safe	safe	ADJ
admet-1271	72	28	,	,	PUNCT
admet-1271	72	29	effective	effective	ADJ
admet-1271	72	30	,	,	PUNCT
admet-1271	72	31	on	on	ADP
admet-1271	72	32	target	target	NOUN
admet-1271	72	33	and	and	CCONJ
admet-1271	72	34	innovative	innovative	ADJ
admet-1271	72	35	new	new	ADJ
admet-1271	72	36	compounds	compound	NOUN
admet-1271	72	37	[	[	X
admet-1271	72	38	5,12	5,12	NUM
admet-1271	72	39	]	]	PUNCT
admet-1271	72	40	.	.	PUNCT
admet-1271	73	1	final	final	ADJ
admet-1271	73	2	thoughts	thought	NOUN
admet-1271	73	3	the	the	DET
admet-1271	73	4	findings	finding	NOUN
admet-1271	73	5	from	from	ADP
admet-1271	73	6	2021	2021	NUM
admet-1271	73	7	who	who	PRON
admet-1271	73	8	antibacterial	antibacterial	ADJ
admet-1271	73	9	pipeline	pipeline	NOUN
admet-1271	73	10	analysis	analysis	NOUN
admet-1271	73	11	confirm	confirm	VERB
admet-1271	73	12	that	that	SCONJ
admet-1271	73	13	r&d	r&d	NOUN
admet-1271	73	14	is	be	AUX
admet-1271	73	15	driven	drive	VERB
admet-1271	73	16	by	by	ADP
admet-1271	73	17	private	private	ADJ
admet-1271	73	18	pharmaceutical	pharmaceutical	ADJ
admet-1271	73	19	companies	company	NOUN
admet-1271	73	20	,	,	PUNCT
admet-1271	73	21	but	but	CCONJ
admet-1271	73	22	the	the	DET
admet-1271	73	23	progress	progress	NOUN
admet-1271	73	24	made	make	VERB
admet-1271	73	25	since	since	SCONJ
admet-1271	73	26	last	last	ADJ
admet-1271	73	27	year	year	NOUN
admet-1271	73	28	are	be	AUX
admet-1271	73	29	extremely	extremely	ADV
admet-1271	73	30	modest	modest	ADJ
admet-1271	73	31	with	with	ADP
admet-1271	73	32	only	only	ADV
admet-1271	73	33	one	one	NUM
admet-1271	73	34	product	product	NOUN
admet-1271	73	35	obtaining	obtain	VERB
admet-1271	73	36	marketing	marketing	NOUN
admet-1271	73	37	authorization	authorization	NOUN
admet-1271	73	38	in	in	ADP
admet-1271	73	39	china	china	PROPN
admet-1271	73	40	,	,	PUNCT
admet-1271	73	41	one	one	NUM
admet-1271	73	42	new	new	ADJ
admet-1271	73	43	product	product	NOUN
admet-1271	73	44	entering	enter	VERB
admet-1271	73	45	phase	phase	NOUN
admet-1271	73	46	3	3	NUM
admet-1271	73	47	and	and	CCONJ
admet-1271	73	48	five	five	NUM
admet-1271	73	49	products	product	NOUN
admet-1271	73	50	entering	enter	VERB
admet-1271	73	51	phase	phase	NOUN
admet-1271	73	52	1	1	NUM
admet-1271	73	53	and	and	CCONJ
admet-1271	73	54	7	7	NUM
admet-1271	73	55	products	product	NOUN
admet-1271	73	56	terminating	terminate	VERB
admet-1271	73	57	their	their	PRON
admet-1271	73	58	development	development	NOUN
admet-1271	73	59	.	.	PUNCT
admet-1271	74	1	smaller	small	ADJ
admet-1271	74	2	biotechs	biotech	NOUN
admet-1271	74	3	are	be	AUX
admet-1271	74	4	facing	face	VERB
admet-1271	74	5	major	major	ADJ
admet-1271	74	6	challenges	challenge	NOUN
admet-1271	74	7	,	,	PUNCT
admet-1271	74	8	and	and	CCONJ
admet-1271	74	9	the	the	DET
admet-1271	74	10	number	number	NOUN
admet-1271	74	11	of	of	ADP
admet-1271	74	12	overall	overall	ADJ
admet-1271	74	13	programs	program	NOUN
admet-1271	74	14	are	be	AUX
admet-1271	74	15	still	still	ADV
admet-1271	74	16	largely	largely	ADV
admet-1271	74	17	insufficient	insufficient	ADJ
admet-1271	74	18	to	to	PART
admet-1271	74	19	properly	properly	ADV
admet-1271	74	20	address	address	VERB
admet-1271	74	21	the	the	DET
admet-1271	74	22	burden	burden	NOUN
admet-1271	74	23	of	of	ADP
admet-1271	74	24	amr	amr	PROPN
admet-1271	74	25	.	.	PROPN
admet-1271	74	26	antibacterial	antibacterial	ADJ
admet-1271	74	27	agents	agent	NOUN
admet-1271	74	28	in	in	ADP
admet-1271	74	29	clinical	clinical	ADJ
admet-1271	74	30	development	development	NOUN
admet-1271	74	31	do	do	AUX
admet-1271	74	32	not	not	PART
admet-1271	74	33	conclusively	conclusively	ADV
admet-1271	74	34	address	address	VERB
admet-1271	74	35	the	the	DET
admet-1271	74	36	problem	problem	NOUN
admet-1271	74	37	of	of	ADP
admet-1271	74	38	extensive	extensive	ADJ
admet-1271	74	39	or	or	CCONJ
admet-1271	74	40	pandrug	pandrug	NOUN
admet-1271	74	41	-	-	PUNCT
admet-1271	74	42	resistant	resistant	ADJ
admet-1271	74	43	gram	gram	NOUN
admet-1271	74	44	-	-	PUNCT
admet-1271	74	45	negative	negative	ADJ
admet-1271	74	46	bacteria	bacteria	NOUN
admet-1271	74	47	.	.	PUNCT
admet-1271	75	1	novel	novel	ADJ
admet-1271	75	2	antibiotics	antibiotic	NOUN
admet-1271	75	3	targeting	target	VERB
admet-1271	75	4	the	the	DET
admet-1271	75	5	critical	critical	ADJ
admet-1271	75	6	who	who	PRON
admet-1271	75	7	priority	priority	VERB
admet-1271	75	8	pathogens	pathogen	NOUN
admet-1271	75	9	,	,	PUNCT
admet-1271	75	10	are	be	AUX
admet-1271	75	11	still	still	ADV
admet-1271	75	12	lacking	lack	VERB
admet-1271	75	13	,	,	PUNCT
admet-1271	75	14	in	in	ADP
admet-1271	75	15	particular	particular	ADJ
admet-1271	75	16	,	,	PUNCT
admet-1271	75	17	carbapenem	carbapenem	NOUN
admet-1271	75	18	-	-	PUNCT
admet-1271	75	19	resistant	resistant	ADJ
admet-1271	75	20	a.	a.	NOUN
admet-1271	75	21	baumannii	baumannii	NOUN
admet-1271	75	22	and	and	CCONJ
admet-1271	75	23	p.	p.	PROPN
admet-1271	75	24	aeruginosa	aeruginosa	PROPN
admet-1271	75	25	.	.	PUNCT
admet-1271	76	1	the	the	DET
admet-1271	76	2	pipeline	pipeline	NOUN
admet-1271	76	3	also	also	ADV
admet-1271	76	4	lacks	lack	VERB
admet-1271	76	5	oral	oral	ADJ
admet-1271	76	6	antibiotic	antibiotic	ADJ
admet-1271	76	7	treatment	treatment	NOUN
admet-1271	76	8	options	option	NOUN
admet-1271	76	9	for	for	ADP
admet-1271	76	10	extended	extended	ADJ
admet-1271	76	11	spectrum	spectrum	NOUN
admet-1271	76	12	β	β	NOUN
admet-1271	76	13	-	-	NOUN
admet-1271	76	14	lactamases	lactamase	NOUN
admet-1271	76	15	(	(	PUNCT
admet-1271	76	16	esbls	esbls	PROPN
admet-1271	76	17	)	)	PUNCT
admet-1271	76	18	and	and	CCONJ
admet-1271	76	19	cre	cre	PROPN
admet-1271	76	20	,	,	PUNCT
admet-1271	76	21	which	which	PRON
admet-1271	76	22	could	could	AUX
admet-1271	76	23	allow	allow	VERB
admet-1271	76	24	for	for	ADP
admet-1271	76	25	treatments	treatment	NOUN
admet-1271	76	26	outside	outside	ADP
admet-1271	76	27	the	the	DET
admet-1271	76	28	hospital	hospital	NOUN
admet-1271	76	29	-	-	PUNCT
admet-1271	76	30	setting	setting	NOUN
admet-1271	76	31	,	,	PUNCT
admet-1271	76	32	and	and	CCONJ
admet-1271	76	33	shorter	short	ADJ
admet-1271	76	34	treatment	treatment	NOUN
admet-1271	76	35	duration	duration	NOUN
admet-1271	76	36	.	.	PUNCT
admet-1271	77	1	in	in	ADP
admet-1271	77	2	addition	addition	NOUN
admet-1271	77	3	,	,	PUNCT
admet-1271	77	4	optimized	optimize	VERB
admet-1271	77	5	pediatric	pediatric	ADJ
admet-1271	77	6	formulations	formulation	NOUN
admet-1271	77	7	of	of	ADP
admet-1271	77	8	existing	exist	VERB
admet-1271	77	9	antibiotics	antibiotic	NOUN
admet-1271	77	10	are	be	AUX
admet-1271	77	11	also	also	ADV
admet-1271	77	12	needed	need	VERB
admet-1271	77	13	,	,	PUNCT
admet-1271	77	14	and	and	CCONJ
admet-1271	77	15	there	there	PRON
admet-1271	77	16	are	be	VERB
admet-1271	77	17	barely	barely	ADV
admet-1271	77	18	any	any	DET
admet-1271	77	19	active	active	ADJ
admet-1271	77	20	pediatric	pediatric	ADJ
admet-1271	77	21	development	development	NOUN
admet-1271	77	22	programs	program	NOUN
admet-1271	77	23	.	.	PUNCT
admet-1271	78	1	overall	overall	ADV
admet-1271	78	2	,	,	PUNCT
admet-1271	78	3	the	the	DET
admet-1271	78	4	recently	recently	ADV
admet-1271	78	5	approved	approve	VERB
admet-1271	78	6	antibacterial	antibacterial	ADJ
admet-1271	78	7	agents	agent	NOUN
admet-1271	78	8	combined	combine	VERB
admet-1271	78	9	with	with	ADP
admet-1271	78	10	the	the	DET
admet-1271	78	11	late	late	ADJ
admet-1271	78	12	-	-	PUNCT
admet-1271	78	13	stage	stage	NOUN
admet-1271	78	14	traditional	traditional	ADJ
admet-1271	78	15	agents	agent	NOUN
admet-1271	78	16	under	under	ADP
admet-1271	78	17	development	development	NOUN
admet-1271	78	18	are	be	AUX
admet-1271	78	19	insufficient	insufficient	ADJ
admet-1271	78	20	to	to	PART
admet-1271	78	21	address	address	VERB
admet-1271	78	22	the	the	DET
admet-1271	78	23	enormous	enormous	ADJ
admet-1271	78	24	threat	threat	NOUN
admet-1271	78	25	posed	pose	VERB
admet-1271	78	26	by	by	ADP
admet-1271	78	27	amr	amr	PROPN
admet-1271	78	28	.	.	PROPN
admet-1271	78	29	more	more	ADJ
admet-1271	78	30	novel	novel	ADJ
admet-1271	78	31	compounds	compound	NOUN
admet-1271	78	32	that	that	PRON
admet-1271	78	33	address	address	NOUN
admet-1271	78	34	unmet	unmet	NOUN
admet-1271	78	35	clinical	clinical	ADJ
admet-1271	78	36	needs	need	NOUN
admet-1271	78	37	are	be	AUX
admet-1271	78	38	needed	need	VERB
admet-1271	78	39	.	.	PUNCT
admet-1271	79	1	these	these	DET
admet-1271	79	2	compounds	compound	NOUN
admet-1271	79	3	must	must	AUX
admet-1271	79	4	elude	elude	VERB
admet-1271	79	5	known	know	VERB
admet-1271	79	6	mechanisms	mechanism	NOUN
admet-1271	79	7	of	of	ADP
admet-1271	79	8	drug	drug	NOUN
admet-1271	79	9	resistance	resistance	NOUN
admet-1271	79	10	,	,	PUNCT
admet-1271	79	11	and	and	CCONJ
admet-1271	79	12	fit	fit	ADJ
admet-1271	79	13	into	into	ADP
admet-1271	79	14	modern	modern	ADJ
admet-1271	79	15	reimbursement	reimbursement	NOUN
admet-1271	79	16	mechanisms	mechanism	NOUN
admet-1271	79	17	.	.	PUNCT
admet-1271	80	1	global	global	ADJ
admet-1271	80	2	public	public	ADJ
admet-1271	80	3	health	health	NOUN
admet-1271	80	4	efforts	effort	NOUN
admet-1271	80	5	continue	continue	VERB
admet-1271	80	6	to	to	PART
admet-1271	80	7	focus	focus	VERB
admet-1271	80	8	on	on	ADP
admet-1271	80	9	the	the	DET
admet-1271	80	10	relentless	relentless	ADJ
admet-1271	80	11	covid-19	covid-19	PROPN
admet-1271	80	12	pandemic	pandemic	NOUN
admet-1271	80	13	;	;	PUNCT
admet-1271	80	14	resources	resource	NOUN
admet-1271	80	15	are	be	AUX
admet-1271	80	16	further	far	ADV
admet-1271	80	17	diverted	divert	VERB
admet-1271	80	18	from	from	ADP
admet-1271	80	19	other	other	ADJ
admet-1271	80	20	public	public	ADJ
admet-1271	80	21	health	health	NOUN
admet-1271	80	22	priorities	priority	NOUN
admet-1271	80	23	,	,	PUNCT
admet-1271	80	24	including	include	VERB
admet-1271	80	25	amr	amr	NOUN
admet-1271	80	26	.	.	PROPN
admet-1271	80	27	this	this	PRON
admet-1271	80	28	has	have	AUX
admet-1271	80	29	also	also	ADV
admet-1271	80	30	impacted	impact	VERB
admet-1271	80	31	clinical	clinical	ADJ
admet-1271	80	32	and	and	CCONJ
admet-1271	80	33	preclinical	preclinical	ADJ
admet-1271	80	34	developments	development	NOUN
admet-1271	80	35	,	,	PUNCT
admet-1271	80	36	which	which	PRON
admet-1271	80	37	have	have	AUX
admet-1271	80	38	been	be	AUX
admet-1271	80	39	substantially	substantially	ADV
admet-1271	80	40	halted	halt	VERB
admet-1271	80	41	by	by	ADP
admet-1271	80	42	the	the	DET
admet-1271	80	43	covid-19	covid-19	PROPN
admet-1271	80	44	outbreak	outbreak	NOUN
admet-1271	80	45	,	,	PUNCT
admet-1271	80	46	with	with	ADP
admet-1271	80	47	most	most	ADJ
admet-1271	80	48	programmes	programme	NOUN
admet-1271	80	49	incurring	incur	VERB
admet-1271	80	50	considerable	considerable	ADJ
admet-1271	80	51	costs	cost	NOUN
admet-1271	80	52	and	and	CCONJ
admet-1271	80	53	delays	delay	NOUN
admet-1271	80	54	likely	likely	ADJ
admet-1271	80	55	for	for	ADP
admet-1271	80	56	years	year	NOUN
admet-1271	80	57	to	to	PART
admet-1271	80	58	come	come	VERB
admet-1271	80	59	.	.	PUNCT
admet-1271	81	1	a	a	DET
admet-1271	81	2	global	global	ADJ
admet-1271	81	3	response	response	NOUN
admet-1271	81	4	is	be	AUX
admet-1271	81	5	needed	need	VERB
admet-1271	81	6	to	to	PART
admet-1271	81	7	regain	regain	VERB
admet-1271	81	8	the	the	DET
admet-1271	81	9	time	time	NOUN
admet-1271	81	10	lost	lose	VERB
admet-1271	81	11	in	in	ADP
admet-1271	81	12	the	the	DET
admet-1271	81	13	race	race	NOUN
admet-1271	81	14	against	against	ADP
admet-1271	81	15	the	the	DET
admet-1271	81	16	silent	silent	ADJ
admet-1271	81	17	amr	amr	NOUN
admet-1271	81	18	pandemic	pandemic	ADJ
admet-1271	81	19	lurking	lurking	NOUN
admet-1271	81	20	in	in	ADP
admet-1271	81	21	the	the	DET
admet-1271	81	22	shadows	shadow	NOUN
admet-1271	81	23	,	,	PUNCT
admet-1271	81	24	waiting	wait	VERB
admet-1271	81	25	for	for	ADP
admet-1271	81	26	its	its	PRON
admet-1271	81	27	turn	turn	NOUN
admet-1271	81	28	.	.	PUNCT
admet-1271	82	1	admet	admet	PROPN
admet-1271	82	2	&	&	CCONJ
admet-1271	82	3	dmpk	dmpk	PROPN
admet-1271	82	4	10(2	10(2	NUM
admet-1271	82	5	)	)	PUNCT
admet-1271	82	6	(	(	PUNCT
admet-1271	82	7	2022	2022	NUM
admet-1271	82	8	)	)	PUNCT
admet-1271	82	9	147	147	NUM
admet-1271	82	10	-	-	SYM
admet-1271	82	11	151	151	NUM
admet-1271	82	12	challenges	challenge	NOUN
admet-1271	82	13	in	in	ADP
admet-1271	82	14	antibacterial	antibacterial	ADJ
admet-1271	82	15	drug	drug	NOUN
admet-1271	82	16	development	development	NOUN
admet-1271	82	17	doi	doi	PROPN
admet-1271	82	18	:	:	PUNCT
admet-1271	82	19	http://dx.doi.org/10.5599/admet.1271	http://dx.doi.org/10.5599/admet.1271	X
admet-1271	82	20	151	151	NUM
admet-1271	82	21	conflict	conflict	NOUN
admet-1271	82	22	of	of	ADP
admet-1271	82	23	interest	interest	NOUN
admet-1271	82	24	:	:	PUNCT
admet-1271	82	25	no	no	DET
admet-1271	82	26	conflict	conflict	NOUN
admet-1271	82	27	of	of	ADP
admet-1271	82	28	interest	interest	NOUN
admet-1271	82	29	is	be	AUX
admet-1271	82	30	declared	declare	VERB
admet-1271	82	31	by	by	ADP
admet-1271	82	32	the	the	DET
admet-1271	82	33	authors	author	NOUN
admet-1271	82	34	.	.	PUNCT
admet-1271	83	1	references	reference	NOUN
admet-1271	83	2	[	[	X
admet-1271	83	3	1	1	NUM
admet-1271	83	4	]	]	X
admet-1271	83	5	c.j	c.j	PROPN
admet-1271	83	6	.	.	PROPN
admet-1271	83	7	murray	murray	PROPN
admet-1271	83	8	,	,	PUNCT
admet-1271	83	9	k.s	k.s	PROPN
admet-1271	83	10	.	.	PROPN
admet-1271	83	11	ikuta	ikuta	PROPN
admet-1271	83	12	,	,	PUNCT
admet-1271	83	13	f.	f.	PROPN
admet-1271	83	14	sharara	sharara	PROPN
admet-1271	83	15	,	,	PUNCT
admet-1271	83	16	l.	l.	PROPN
admet-1271	83	17	swetschinski	swetschinski	PROPN
admet-1271	83	18	,	,	PUNCT
admet-1271	83	19	g.r	g.r	PROPN
admet-1271	83	20	.	.	PROPN
admet-1271	83	21	aguilar	aguilar	PROPN
admet-1271	83	22	,	,	PUNCT
admet-1271	83	23	a.	a.	NOUN
admet-1271	83	24	gray	gray	PROPN
admet-1271	83	25	,	,	PUNCT
admet-1271	83	26	c.	c.	PROPN
admet-1271	83	27	han	han	PROPN
admet-1271	83	28	,	,	PUNCT
admet-1271	83	29	c.	c.	PROPN
admet-1271	83	30	bisignano	bisignano	PROPN
admet-1271	83	31	,	,	PUNCT
admet-1271	83	32	p.	p.	PROPN
admet-1271	83	33	rao	rao	PROPN
admet-1271	83	34	,	,	PUNCT
admet-1271	83	35	e.	e.	PROPN
admet-1271	83	36	wool	wool	PROPN
admet-1271	83	37	,	,	PUNCT
admet-1271	83	38	s.c	s.c	PROPN
admet-1271	83	39	.	.	PROPN
admet-1271	83	40	johnson	johnson	PROPN
admet-1271	83	41	.	.	PUNCT
admet-1271	84	1	global	global	ADJ
admet-1271	84	2	burden	burden	NOUN
admet-1271	84	3	of	of	ADP
admet-1271	84	4	bacterial	bacterial	ADJ
admet-1271	84	5	antimicrobial	antimicrobial	ADJ
admet-1271	84	6	resistance	resistance	NOUN
admet-1271	84	7	in	in	ADP
admet-1271	84	8	2019	2019	NUM
admet-1271	84	9	:	:	PUNCT
admet-1271	84	10	a	a	DET
admet-1271	84	11	systematic	systematic	ADJ
admet-1271	84	12	analysis	analysis	NOUN
admet-1271	84	13	.	.	PUNCT
admet-1271	85	1	the	the	DET
admet-1271	85	2	lancet	lancet	NOUN
admet-1271	85	3	399	399	NUM
admet-1271	85	4	(	(	PUNCT
admet-1271	85	5	2022	2022	NUM
admet-1271	85	6	)	)	PUNCT
admet-1271	85	7	p629	p629	NUM
admet-1271	85	8	-	-	SYM
admet-1271	85	9	655	655	NUM
admet-1271	85	10	.	.	PUNCT
admet-1271	85	11	https://doi.org/10.1016/s0140-6736(21)02724-0	https://doi.org/10.1016/s0140-6736(21)02724-0	NOUN
admet-1271	85	12	.	.	PUNCT
admet-1271	86	1	[	[	X
admet-1271	86	2	2	2	NUM
admet-1271	86	3	]	]	X
admet-1271	86	4	m.s	m.s	PROPN
admet-1271	86	5	.	.	PROPN
admet-1271	86	6	butler	butler	PROPN
admet-1271	86	7	,	,	PUNCT
admet-1271	86	8	v.	v.	PROPN
admet-1271	86	9	gigante	gigante	PROPN
admet-1271	86	10	,	,	PUNCT
admet-1271	86	11	h.	h.	PROPN
admet-1271	86	12	sati	sati	PROPN
admet-1271	86	13	,	,	PUNCT
admet-1271	86	14	s.	s.	PROPN
admet-1271	86	15	paulin	paulin	PROPN
admet-1271	86	16	,	,	PUNCT
admet-1271	86	17	l.	l.	PROPN
admet-1271	86	18	al	al	PROPN
admet-1271	86	19	-	-	PUNCT
admet-1271	86	20	sulaiman	sulaiman	PROPN
admet-1271	86	21	,	,	PUNCT
admet-1271	86	22	j.h	j.h	PROPN
admet-1271	86	23	.	.	PROPN
admet-1271	86	24	rex	rex	PROPN
admet-1271	86	25	,	,	PUNCT
admet-1271	86	26	p.	p.	PROPN
admet-1271	86	27	fernandes	fernandes	PROPN
admet-1271	86	28	,	,	PUNCT
admet-1271	86	29	c.a	c.a	PROPN
admet-1271	86	30	.	.	PROPN
admet-1271	86	31	arias	arias	PROPN
admet-1271	86	32	,	,	PUNCT
admet-1271	86	33	m.	m.	NOUN
admet-1271	86	34	paul	paul	PROPN
admet-1271	86	35	,	,	PUNCT
admet-1271	86	36	g.e	g.e	PROPN
admet-1271	86	37	.	.	PROPN
admet-1271	86	38	thwaites	thwaites	PROPN
admet-1271	86	39	,	,	PUNCT
admet-1271	86	40	l.	l.	PROPN
admet-1271	86	41	czaplewski	czaplewski	PROPN
admet-1271	86	42	.	.	PUNCT
admet-1271	87	1	analysis	analysis	NOUN
admet-1271	87	2	of	of	ADP
admet-1271	87	3	the	the	DET
admet-1271	87	4	clinical	clinical	ADJ
admet-1271	87	5	pipeline	pipeline	NOUN
admet-1271	87	6	of	of	ADP
admet-1271	87	7	treatments	treatment	NOUN
admet-1271	87	8	for	for	ADP
admet-1271	87	9	drug	drug	NOUN
admet-1271	87	10	resistant	resistant	ADJ
admet-1271	87	11	bacterial	bacterial	ADJ
admet-1271	87	12	infections	infection	NOUN
admet-1271	87	13	:	:	PUNCT
admet-1271	87	14	despite	despite	SCONJ
admet-1271	87	15	progress	progress	NOUN
admet-1271	87	16	,	,	PUNCT
admet-1271	87	17	more	more	ADJ
admet-1271	87	18	action	action	NOUN
admet-1271	87	19	is	be	AUX
admet-1271	87	20	needed	need	VERB
admet-1271	87	21	.	.	PUNCT
admet-1271	88	1	antimicrobial	antimicrobial	ADJ
admet-1271	88	2	agents	agent	NOUN
admet-1271	88	3	and	and	CCONJ
admet-1271	88	4	chemotherapy	chemotherapy	NOUN
admet-1271	88	5	(	(	PUNCT
admet-1271	88	6	2022	2022	NUM
admet-1271	88	7	)	)	PUNCT
admet-1271	88	8	https://doi.org/10.1128/aac.01991-21	https://doi.org/10.1128/aac.01991-21	NOUN
admet-1271	88	9	.	.	PUNCT
admet-1271	89	1	[	[	X
admet-1271	89	2	3	3	NUM
admet-1271	89	3	]	]	X
admet-1271	89	4	prioritization	prioritization	NOUN
admet-1271	89	5	of	of	ADP
admet-1271	89	6	pathogens	pathogen	NOUN
admet-1271	89	7	to	to	PART
admet-1271	89	8	guide	guide	VERB
admet-1271	89	9	discovery	discovery	NOUN
admet-1271	89	10	,	,	PUNCT
admet-1271	89	11	research	research	NOUN
admet-1271	89	12	,	,	PUNCT
admet-1271	89	13	and	and	CCONJ
admet-1271	89	14	development	development	NOUN
admet-1271	89	15	of	of	ADP
admet-1271	89	16	new	new	ADJ
admet-1271	89	17	antibiotics	antibiotic	NOUN
admet-1271	89	18	for	for	ADP
admet-1271	89	19	drug	drug	NOUN
admet-1271	89	20	-	-	PUNCT
admet-1271	89	21	resistant	resistant	ADJ
admet-1271	89	22	bacterial	bacterial	ADJ
admet-1271	89	23	infections	infection	NOUN
admet-1271	89	24	,	,	PUNCT
admet-1271	89	25	including	include	VERB
admet-1271	89	26	tuberculosis	tuberculosis	NOUN
admet-1271	89	27	.	.	PUNCT
admet-1271	90	1	world	world	PROPN
admet-1271	90	2	health	health	PROPN
admet-1271	90	3	organization	organization	NOUN
admet-1271	90	4	;	;	PUNCT
admet-1271	90	5	2017	2017	NUM
admet-1271	90	6	.	.	PUNCT
admet-1271	91	1	https://apps.who.int/iris/handle/10665/311820	https://apps.who.int/iris/handle/10665/311820	NOUN
admet-1271	91	2	.	.	PUNCT
admet-1271	92	1	[	[	X
admet-1271	92	2	4	4	NUM
admet-1271	92	3	]	]	ADJ
admet-1271	92	4	antibiotics	antibiotic	NOUN
admet-1271	92	5	currently	currently	ADV
admet-1271	92	6	in	in	ADP
admet-1271	92	7	global	global	ADJ
admet-1271	92	8	clinical	clinical	ADJ
admet-1271	92	9	development	development	NOUN
admet-1271	92	10	,	,	PUNCT
admet-1271	92	11	pew	pew	NOUN
admet-1271	92	12	’s	’s	PART
admet-1271	92	13	antibiotic	antibiotic	ADJ
admet-1271	92	14	resistance	resistance	NOUN
admet-1271	92	15	project	project	NOUN
admet-1271	92	16	communication	communication	NOUN
admet-1271	92	17	,	,	PUNCT
admet-1271	92	18	updated	update	VERB
admet-1271	92	19	:	:	PUNCT
admet-1271	92	20	march	march	PROPN
admet-1271	92	21	9	9	NUM
admet-1271	92	22	,	,	PUNCT
admet-1271	92	23	2021	2021	NUM
admet-1271	92	24	.	.	PUNCT
admet-1271	93	1	available	available	ADJ
admet-1271	93	2	via	via	ADP
admet-1271	93	3	:	:	PUNCT
admet-1271	93	4	antibiotics	antibiotic	NOUN
admet-1271	93	5	currently	currently	ADV
admet-1271	93	6	in	in	ADP
admet-1271	93	7	global	global	ADJ
admet-1271	93	8	clinical	clinical	ADJ
admet-1271	93	9	development	development	NOUN
admet-1271	93	10	|	|	ADP
admet-1271	93	11	the	the	DET
admet-1271	93	12	pew	pew	NOUN
admet-1271	93	13	charitable	charitable	ADJ
admet-1271	93	14	trusts	trust	NOUN
admet-1271	93	15	(	(	PUNCT
admet-1271	93	16	pewtrusts.org	pewtrusts.org	X
admet-1271	93	17	)	)	PUNCT
admet-1271	93	18	(	(	PUNCT
admet-1271	93	19	last	last	ADV
admet-1271	93	20	accessed	access	VERB
admet-1271	93	21	01/27/2022	01/27/2022	NOUN
admet-1271	93	22	)	)	PUNCT
admet-1271	93	23	.	.	PUNCT
admet-1271	94	1	[	[	X
admet-1271	94	2	5	5	NUM
admet-1271	94	3	]	]	SYM
admet-1271	94	4	2020	2020	NUM
admet-1271	94	5	antibacterial	antibacterial	ADJ
admet-1271	94	6	agents	agent	NOUN
admet-1271	94	7	in	in	ADP
admet-1271	94	8	clinical	clinical	ADJ
admet-1271	94	9	and	and	CCONJ
admet-1271	94	10	preclinical	preclinical	ADJ
admet-1271	94	11	development	development	NOUN
admet-1271	94	12	:	:	PUNCT
admet-1271	94	13	an	an	DET
admet-1271	94	14	overview	overview	NOUN
admet-1271	94	15	and	and	CCONJ
admet-1271	94	16	analysis	analysis	NOUN
admet-1271	94	17	.	.	PUNCT
admet-1271	95	1	geneva	geneva	NOUN
admet-1271	95	2	:	:	PUNCT
admet-1271	95	3	world	world	PROPN
admet-1271	95	4	health	health	NOUN
admet-1271	95	5	organization	organization	NOUN
admet-1271	95	6	;	;	PUNCT
admet-1271	95	7	2021	2021	NUM
admet-1271	95	8	.	.	PUNCT
admet-1271	96	1	licence	licence	NOUN
admet-1271	96	2	:	:	PUNCT
admet-1271	96	3	cc	cc	VERB
admet-1271	96	4	by	by	ADP
admet-1271	96	5	-	-	PUNCT
admet-1271	96	6	nc	nc	PROPN
admet-1271	96	7	-	-	PUNCT
admet-1271	96	8	sa	sa	PROPN
admet-1271	96	9	3.0	3.0	NUM
admet-1271	96	10	igo	igo	NOUN
admet-1271	96	11	.	.	PUNCT
admet-1271	97	1	[	[	X
admet-1271	97	2	6	6	NUM
admet-1271	97	3	]	]	PUNCT
admet-1271	97	4	who	who	PRON
admet-1271	97	5	global	global	ADJ
admet-1271	97	6	observatory	observatory	NOUN
admet-1271	97	7	on	on	ADP
admet-1271	97	8	health	health	NOUN
admet-1271	97	9	research	research	NOUN
admet-1271	97	10	and	and	CCONJ
admet-1271	97	11	development	development	NOUN
admet-1271	97	12	.	.	PUNCT
admet-1271	98	1	available	available	ADJ
admet-1271	98	2	via	via	ADP
admet-1271	98	3	:	:	PUNCT
admet-1271	98	4	https://www.who.int/observatories/global-observatory-on-health-research-anddevelopment/monitoring/antibacterial-products-in-clinical-development-for-priority-pathogens	https://www.who.int/observatories/global-observatory-on-health-research-anddevelopment/monitoring/antibacterial-products-in-clinical-development-for-priority-pathogen	NOUN
admet-1271	98	5	.	.	PUNCT
admet-1271	99	1	(	(	PUNCT
admet-1271	99	2	last	last	ADJ
admet-1271	99	3	accessed	access	VERB
admet-1271	99	4	01/27/2022	01/27/2022	NOUN
admet-1271	99	5	)	)	PUNCT
admet-1271	99	6	.	.	PUNCT
admet-1271	100	1	[	[	X
admet-1271	100	2	7	7	X
admet-1271	100	3	]	]	X
admet-1271	100	4	the	the	DET
admet-1271	100	5	global	global	ADJ
admet-1271	100	6	amr	amr	PROPN
admet-1271	100	7	r&d	r&d	PROPN
admet-1271	100	8	hub	hub	NOUN
admet-1271	100	9	’s	’s	PART
admet-1271	100	10	dynamic	dynamic	ADJ
admet-1271	100	11	dashboard	dashboard	NOUN
admet-1271	100	12	.	.	PUNCT
admet-1271	101	1	pipeline	pipeline	NOUN
admet-1271	101	2	gallery	gallery	PROPN
admet-1271	101	3	.	.	PUNCT
admet-1271	102	1	available	available	ADJ
admet-1271	102	2	via	via	ADP
admet-1271	102	3	:	:	PUNCT
admet-1271	102	4	https://globalamrhub.org/dynamic-dashboard/pipeline-gallery/	https://globalamrhub.org/dynamic-dashboard/pipeline-gallery/	PROPN
admet-1271	102	5	(	(	PUNCT
admet-1271	102	6	last	last	ADV
admet-1271	102	7	accessed	access	VERB
admet-1271	102	8	01/27/2022	01/27/2022	NOUN
admet-1271	102	9	)	)	PUNCT
admet-1271	102	10	.	.	PUNCT
admet-1271	103	1	[	[	X
admet-1271	103	2	8	8	X
admet-1271	103	3	]	]	PUNCT
admet-1271	103	4	a	a	DET
admet-1271	103	5	financial	financial	ADJ
admet-1271	103	6	model	model	NOUN
admet-1271	103	7	for	for	ADP
admet-1271	103	8	an	an	DET
admet-1271	103	9	impact	impact	NOUN
admet-1271	103	10	investment	investment	NOUN
admet-1271	103	11	fund	fund	NOUN
admet-1271	103	12	for	for	ADP
admet-1271	103	13	the	the	DET
admet-1271	103	14	development	development	NOUN
admet-1271	103	15	of	of	ADP
admet-1271	103	16	antibacterial	antibacterial	ADJ
admet-1271	103	17	treatments	treatment	NOUN
admet-1271	103	18	and	and	CCONJ
admet-1271	103	19	diagnostics	diagnostic	NOUN
admet-1271	103	20	:	:	PUNCT
admet-1271	103	21	a	a	DET
admet-1271	103	22	user	user	NOUN
admet-1271	103	23	guide	guide	NOUN
admet-1271	103	24	.	.	PUNCT
admet-1271	104	1	geneva	geneva	PROPN
admet-1271	104	2	:	:	PUNCT
admet-1271	104	3	world	world	PROPN
admet-1271	104	4	health	health	NOUN
admet-1271	104	5	organization	organization	NOUN
admet-1271	104	6	;	;	PUNCT
admet-1271	104	7	2020	2020	NUM
admet-1271	104	8	.	.	PUNCT
admet-1271	105	1	licence	licence	NOUN
admet-1271	105	2	:	:	PUNCT
admet-1271	105	3	cc	cc	VERB
admet-1271	105	4	by	by	ADP
admet-1271	105	5	-	-	PUNCT
admet-1271	105	6	nc	nc	PROPN
admet-1271	105	7	-	-	PUNCT
admet-1271	105	8	sa	sa	PROPN
admet-1271	105	9	3.0	3.0	NUM
admet-1271	105	10	igo	igo	NOUN
admet-1271	105	11	.	.	PUNCT
admet-1271	106	1	[	[	X
admet-1271	106	2	9	9	NUM
admet-1271	106	3	]	]	PUNCT
admet-1271	106	4	m.	m.	NOUN
admet-1271	106	5	sharland	sharland	NOUN
admet-1271	106	6	,	,	PUNCT
admet-1271	106	7	c.	c.	PROPN
admet-1271	106	8	pulcini	pulcini	PROPN
admet-1271	106	9	,	,	PUNCT
admet-1271	106	10	s.	s.	PROPN
admet-1271	106	11	harbarth	harbarth	PROPN
admet-1271	106	12	,	,	PUNCT
admet-1271	106	13	m.	m.	PROPN
admet-1271	106	14	zeng	zeng	PROPN
admet-1271	106	15	,	,	PUNCT
admet-1271	106	16	s.	s.	PROPN
admet-1271	106	17	gandra	gandra	PROPN
admet-1271	106	18	,	,	PUNCT
admet-1271	106	19	s.	s.	PROPN
admet-1271	106	20	mathur	mathur	PROPN
admet-1271	106	21	,	,	PUNCT
admet-1271	106	22	n.	n.	PROPN
admet-1271	106	23	magrini	magrini	PROPN
admet-1271	106	24	.	.	PUNCT
admet-1271	106	25	classifying	classify	VERB
admet-1271	106	26	antibiotics	antibiotic	NOUN
admet-1271	106	27	in	in	ADP
admet-1271	106	28	the	the	DET
admet-1271	106	29	who	who	PRON
admet-1271	106	30	essential	essential	ADJ
admet-1271	106	31	medicines	medicine	NOUN
admet-1271	106	32	list	list	NOUN
admet-1271	106	33	for	for	ADP
admet-1271	106	34	optimal	optimal	ADJ
admet-1271	106	35	use	use	NOUN
admet-1271	106	36	—	—	PUNCT
admet-1271	106	37	be	be	AUX
admet-1271	106	38	aware	aware	ADJ
admet-1271	106	39	.	.	PUNCT
admet-1271	107	1	the	the	DET
admet-1271	107	2	lancet	lancet	ADJ
admet-1271	107	3	infectious	infectious	ADJ
admet-1271	107	4	diseases	disease	NOUN
admet-1271	107	5	18	18	NUM
admet-1271	107	6	(	(	PUNCT
admet-1271	107	7	2018	2018	NUM
admet-1271	107	8	)	)	PUNCT
admet-1271	107	9	18	18	NUM
admet-1271	107	10	-	-	SYM
admet-1271	107	11	20	20	NUM
admet-1271	107	12	.	.	PUNCT
admet-1271	108	1	https://doi.org/10.1016/s1473-3099(17)30724-7	https://doi.org/10.1016/s1473-3099(17)30724-7	PROPN
admet-1271	108	2	.	.	PUNCT
admet-1271	109	1	[	[	X
admet-1271	109	2	10	10	NUM
admet-1271	109	3	]	]	SYM
admet-1271	109	4	2021	2021	NUM
admet-1271	109	5	aware	aware	ADJ
admet-1271	109	6	classification	classification	NOUN
admet-1271	109	7	.	.	PUNCT
admet-1271	110	1	who	who	PRON
admet-1271	110	2	access	access	VERB
admet-1271	110	3	,	,	PUNCT
admet-1271	110	4	watch	watch	NOUN
admet-1271	110	5	,	,	PUNCT
admet-1271	110	6	reserve	reserve	NOUN
admet-1271	110	7	,	,	PUNCT
admet-1271	110	8	classification	classification	NOUN
admet-1271	110	9	of	of	ADP
admet-1271	110	10	antibiotics	antibiotic	NOUN
admet-1271	110	11	for	for	ADP
admet-1271	110	12	evaluation	evaluation	NOUN
admet-1271	110	13	and	and	CCONJ
admet-1271	110	14	monitoring	monitoring	NOUN
admet-1271	110	15	of	of	ADP
admet-1271	110	16	use	use	NOUN
admet-1271	110	17	.	.	PUNCT
admet-1271	111	1	who	who	PRON
admet-1271	111	2	reference	reference	VERB
admet-1271	111	3	number	number	NOUN
admet-1271	111	4	:	:	PUNCT
admet-1271	111	5	who	who	PRON
admet-1271	111	6	/	/	SYM
admet-1271	111	7	hmp	hmp	ADJ
admet-1271	111	8	/	/	SYM
admet-1271	111	9	hps	hps	NOUN
admet-1271	111	10	/	/	SYM
admet-1271	111	11	eml/2021.04	eml/2021.04	NOUN
admet-1271	111	12	copyright	copyright	NOUN
admet-1271	111	13	cc	cc	ADP
admet-1271	111	14	bync	bync	NOUN
admet-1271	111	15	-	-	PUNCT
admet-1271	111	16	sa	sa	PROPN
admet-1271	111	17	3.0	3.0	NUM
admet-1271	111	18	igo	igo	NOUN
admet-1271	111	19	.	.	PUNCT
admet-1271	112	1	avaliable	avaliable	ADJ
admet-1271	112	2	via	via	ADP
admet-1271	112	3	:	:	PUNCT
admet-1271	112	4	https://www.who.int/publications/i/item/2021-aware-classification	https://www.who.int/publications/i/item/2021-aware-classification	NOUN
admet-1271	112	5	(	(	PUNCT
admet-1271	112	6	last	last	ADV
admet-1271	112	7	accessed	access	VERB
admet-1271	112	8	on	on	ADP
admet-1271	112	9	27/01/2022	27/01/2022	NUM
admet-1271	112	10	)	)	PUNCT
admet-1271	112	11	.	.	PUNCT
admet-1271	113	1	[	[	X
admet-1271	113	2	11	11	NUM
admet-1271	113	3	]	]	X
admet-1271	113	4	b.n	b.n	PROPN
admet-1271	113	5	.	.	PROPN
admet-1271	113	6	tse	tse	PROPN
admet-1271	113	7	,	,	PUNCT
admet-1271	113	8	a.a	a.a	PROPN
admet-1271	113	9	:	:	PUNCT
admet-1271	113	10	adalja	adalja	PROPN
admet-1271	113	11	,	,	PUNCT
admet-1271	113	12	c.	c.	PROPN
admet-1271	113	13	houchens	houchens	PROPN
admet-1271	113	14	,	,	PUNCT
admet-1271	113	15	j.	j.	PROPN
admet-1271	113	16	larsen	larsen	PROPN
admet-1271	113	17	,	,	PUNCT
admet-1271	113	18	t.v	t.v	PROPN
admet-1271	113	19	.	.	PROPN
admet-1271	113	20	inglesby	inglesby	PROPN
admet-1271	113	21	,	,	PUNCT
admet-1271	113	22	r.	r.	PROPN
admet-1271	113	23	hatchett	hatchett	PROPN
admet-1271	113	24	.	.	PUNCT
admet-1271	114	1	challenges	challenge	NOUN
admet-1271	114	2	and	and	CCONJ
admet-1271	114	3	opportunities	opportunity	NOUN
admet-1271	114	4	of	of	ADP
admet-1271	114	5	nontraditional	nontraditional	ADJ
admet-1271	114	6	approaches	approach	NOUN
admet-1271	114	7	to	to	ADP
admet-1271	114	8	treating	treat	VERB
admet-1271	114	9	bacterial	bacterial	ADJ
admet-1271	114	10	infections	infection	NOUN
admet-1271	114	11	.	.	PUNCT
admet-1271	115	1	clinical	clinical	ADJ
admet-1271	115	2	infectious	infectious	ADJ
admet-1271	115	3	diseases	disease	NOUN
admet-1271	115	4	65	65	NUM
admet-1271	115	5	(	(	PUNCT
admet-1271	115	6	2017	2017	NUM
admet-1271	115	7	)	)	PUNCT
admet-1271	115	8	495	495	NUM
admet-1271	115	9	-	-	SYM
admet-1271	115	10	500	500	NUM
admet-1271	115	11	.	.	PUNCT
admet-1271	116	1	https://doi.org/10.1093/cid/cix320	https://doi.org/10.1093/cid/cix320	NOUN
admet-1271	116	2	.	.	PUNCT
admet-1271	117	1	[	[	X
admet-1271	117	2	12	12	NUM
admet-1271	117	3	]	]	X
admet-1271	117	4	u.	u.	PROPN
admet-1271	117	5	theuretzbacher	theuretzbacher	PROPN
admet-1271	117	6	,	,	PUNCT
admet-1271	117	7	l.j	l.j	PROPN
admet-1271	117	8	.	.	PROPN
admet-1271	117	9	piddock	piddock	PROPN
admet-1271	117	10	.	.	PUNCT
admet-1271	118	1	nontraditional	nontraditional	ADJ
admet-1271	118	2	antibacterial	antibacterial	ADJ
admet-1271	118	3	therapeutic	therapeutic	ADJ
admet-1271	118	4	options	option	NOUN
admet-1271	118	5	and	and	CCONJ
admet-1271	118	6	challenges	challenge	NOUN
admet-1271	118	7	.	.	PUNCT
admet-1271	119	1	cell	cell	NOUN
admet-1271	119	2	host	host	NOUN
admet-1271	119	3	&	&	CCONJ
admet-1271	119	4	microbe	microbe	PROPN
admet-1271	119	5	26	26	NUM
admet-1271	119	6	(	(	PUNCT
admet-1271	119	7	2019	2019	NUM
admet-1271	119	8	)	)	PUNCT
admet-1271	119	9	61	61	NUM
admet-1271	119	10	-	-	SYM
admet-1271	119	11	72	72	NUM
admet-1271	119	12	.	.	PUNCT
admet-1271	119	13	https://doi.org/10.1016/j.chom.2019.06.004	https://doi.org/10.1016/j.chom.2019.06.004	NOUN
admet-1271	119	14	.	.	PUNCT
admet-1271	120	1	[	[	X
admet-1271	120	2	13	13	NUM
admet-1271	120	3	]	]	X
admet-1271	120	4	antibacterial	antibacterial	ADJ
admet-1271	120	5	agents	agent	NOUN
admet-1271	120	6	in	in	ADP
admet-1271	120	7	preclinical	preclinical	ADJ
admet-1271	120	8	development	development	NOUN
admet-1271	120	9	:	:	PUNCT
admet-1271	120	10	an	an	DET
admet-1271	120	11	open	open	ADJ
admet-1271	120	12	access	access	NOUN
admet-1271	120	13	database	database	NOUN
admet-1271	120	14	.	.	PUNCT
admet-1271	121	1	geneva	geneva	NOUN
admet-1271	121	2	:	:	PUNCT
admet-1271	121	3	world	world	NOUN
admet-1271	121	4	,	,	PUNCT
admet-1271	121	5	health	health	NOUN
admet-1271	121	6	organization	organization	NOUN
admet-1271	121	7	;	;	PUNCT
admet-1271	121	8	2019	2019	NUM
admet-1271	121	9	(	(	PUNCT
admet-1271	121	10	who	who	PRON
admet-1271	121	11	/	/	SYM
admet-1271	121	12	emp	emp	NOUN
admet-1271	121	13	/	/	SYM
admet-1271	121	14	iau/2019.12	iau/2019.12	NOUN
admet-1271	121	15	)	)	PUNCT
admet-1271	121	16	.	.	PUNCT
admet-1271	122	1	licence	licence	NOUN
admet-1271	122	2	:	:	PUNCT
admet-1271	122	3	cc	cc	VERB
admet-1271	122	4	by	by	ADP
admet-1271	122	5	-	-	PUNCT
admet-1271	122	6	nc	nc	PROPN
admet-1271	122	7	-	-	PUNCT
admet-1271	122	8	sa	sa	PROPN
admet-1271	122	9	3.0	3.0	NUM
admet-1271	122	10	igo	igo	NOUN
admet-1271	122	11	.	.	PUNCT
admet-1271	123	1	[	[	X
admet-1271	123	2	14	14	NUM
admet-1271	123	3	]	]	X
admet-1271	123	4	j.h	j.h	PROPN
admet-1271	123	5	.	.	PROPN
admet-1271	123	6	rex	rex	PROPN
admet-1271	123	7	,	,	PUNCT
admet-1271	123	8	h.f	h.f	PROPN
admet-1271	123	9	.	.	PROPN
admet-1271	123	10	lynch	lynch	PROPN
admet-1271	123	11	,	,	PUNCT
admet-1271	123	12	i.g	i.g	PROPN
admet-1271	123	13	.	.	PROPN
admet-1271	123	14	cohen	cohen	PROPN
admet-1271	123	15	,	,	PUNCT
admet-1271	123	16	j.j	j.j	PROPN
admet-1271	123	17	.	.	PROPN
admet-1271	123	18	darrow	darrow	PROPN
admet-1271	123	19	,	,	PUNCT
admet-1271	123	20	k.	k.	PROPN
admet-1271	123	21	outterson	outterson	PROPN
admet-1271	123	22	.	.	PUNCT
admet-1271	124	1	designing	design	VERB
admet-1271	124	2	development	development	NOUN
admet-1271	124	3	programs	program	NOUN
admet-1271	124	4	for	for	ADP
admet-1271	124	5	nontraditional	nontraditional	ADJ
admet-1271	124	6	antibacterial	antibacterial	ADJ
admet-1271	124	7	agents	agent	NOUN
admet-1271	124	8	.	.	PUNCT
admet-1271	125	1	nature	nature	NOUN
admet-1271	125	2	communications	communication	NOUN
admet-1271	125	3	10	10	NUM
admet-1271	125	4	(	(	PUNCT
admet-1271	125	5	2019	2019	NUM
admet-1271	125	6	)	)	PUNCT
admet-1271	125	7	p61	p61	NOUN
admet-1271	125	8	-	-	SYM
admet-1271	125	9	72	72	NUM
admet-1271	125	10	.	.	PUNCT
admet-1271	125	11	https://doi.org/10.1016/j.chom.2019.06.004	https://doi.org/10.1016/j.chom.2019.06.004	PROPN
admet-1271	125	12	.	.	PUNCT
admet-1271	126	1	©	©	NOUN
admet-1271	126	2	2022	2022	NUM
admet-1271	126	3	by	by	ADP
admet-1271	126	4	the	the	DET
admet-1271	126	5	authors	author	NOUN
admet-1271	126	6	;	;	PUNCT
admet-1271	126	7	licensee	licensee	PROPN
admet-1271	126	8	iapc	iapc	PROPN
admet-1271	126	9	,	,	PUNCT
admet-1271	126	10	zagreb	zagreb	PROPN
admet-1271	126	11	,	,	PUNCT
admet-1271	126	12	croatia	croatia	PROPN
admet-1271	126	13	.	.	PUNCT
admet-1271	127	1	this	this	DET
admet-1271	127	2	article	article	NOUN
admet-1271	127	3	is	be	AUX
admet-1271	127	4	an	an	DET
admet-1271	127	5	open	open	ADJ
admet-1271	127	6	-	-	PUNCT
admet-1271	127	7	access	access	NOUN
admet-1271	127	8	article	article	NOUN
admet-1271	127	9	distributed	distribute	VERB
admet-1271	127	10	under	under	ADP
admet-1271	127	11	the	the	DET
admet-1271	127	12	terms	term	NOUN
admet-1271	127	13	and	and	CCONJ
admet-1271	127	14	conditions	condition	NOUN
admet-1271	127	15	of	of	ADP
admet-1271	127	16	the	the	DET
admet-1271	127	17	creative	creative	ADJ
admet-1271	127	18	commons	common	NOUN
admet-1271	127	19	attribution	attribution	NOUN
admet-1271	127	20	license	license	NOUN
admet-1271	127	21	(	(	PUNCT
admet-1271	127	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-1271	127	23	)	)	PUNCT
admet-1271	127	24	http://dx.doi.org/10.5599/admet.1271	http://dx.doi.org/10.5599/admet.1271	VERB
admet-1271	128	1	https://doi.org/10.1016/s0140-6736(21)02724-0	https://doi.org/10.1016/s0140-6736(21)02724-0	PROPN
admet-1271	128	2	https://doi.org/10.1128/aac.01991-21	https://doi.org/10.1128/aac.01991-21	PROPN
admet-1271	128	3	https://apps.who.int/iris/handle/10665/311820	https://apps.who.int/iris/handle/10665/311820	PROPN
admet-1271	128	4	https://www.pewtrusts.org/en/research-and-analysis/data-visualizations/2014/antibiotics-currently-in-clinical-development	https://www.pewtrusts.org/en/research-and-analysis/data-visualizations/2014/antibiotics-currently-in-clinical-development	PROPN
admet-1271	128	5	https://www.pewtrusts.org/en/research-and-analysis/data-visualizations/2014/antibiotics-currently-in-clinical-development	https://www.pewtrusts.org/en/research-and-analysis/data-visualizations/2014/antibiotics-currently-in-clinical-development	NOUN
admet-1271	128	6	https://www.who.int/observatories/global-observatory-on-health-research-and-development/monitoring/antibacterial-products-in-clinical-development-for-priority-pathogens	https://www.who.int/observatories/global-observatory-on-health-research-and-development/monitoring/antibacterial-products-in-clinical-development-for-priority-pathogen	VERB
admet-1271	128	7	https://www.who.int/observatories/global-observatory-on-health-research-and-development/monitoring/antibacterial-products-in-clinical-development-for-priority-pathogens	https://www.who.int/observatories/global-observatory-on-health-research-and-development/monitoring/antibacterial-products-in-clinical-development-for-priority-pathogens	X
admet-1271	128	8	https://globalamrhub.org/dynamic-dashboard/pipeline-gallery/	https://globalamrhub.org/dynamic-dashboard/pipeline-gallery/	PRON
admet-1271	128	9	https://doi.org/10.1016/s1473-3099(17)30724-7	https://doi.org/10.1016/s1473-3099(17)30724-7	NOUN
admet-1271	128	10	https://www.who.int/publications/i/item/2021-aware-classification	https://www.who.int/publications/i/item/2021-aware-classification	PROPN
admet-1271	128	11	https://doi.org/10.1093/cid/cix320	https://doi.org/10.1093/cid/cix320	PROPN
admet-1271	128	12	https://doi.org/10.1016/j.chom.2019.06.004	https://doi.org/10.1016/j.chom.2019.06.004	NOUN
admet-1271	128	13	https://doi.org/10.1016/j.chom.2019.06.004	https://doi.org/10.1016/j.chom.2019.06.004	NOUN
admet-1271	128	14	https://doi.org/10.1016/j.chom.2019.06.004	https://doi.org/10.1016/j.chom.2019.06.004	PUNCT
admet-1271	128	15	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	NOUN