id	sid	tid	token	lemma	pos
admet-130	1	1	microsoft	microsoft	PROPN
admet-130	1	2	word	word	NOUN
admet-130	1	3	130	130	NUM
admet-130	1	4	-	-	SYM
admet-130	1	5	588	588	NUM
admet-130	1	6	-	-	PUNCT
admet-130	1	7	1	1	NUM
admet-130	1	8	-	-	PUNCT
admet-130	1	9	ed_varadi	ed_varadi	NOUN
admet-130	1	10	doi	doi	NOUN
admet-130	1	11	:	:	PUNCT
admet-130	1	12	10.5599	10.5599	NUM
admet-130	1	13	/	/	SYM
admet-130	1	14	admet.2.4.130	admet.2.4.130	PROPN
admet-130	1	15	272	272	NUM
admet-130	1	16	admet	admet	X
admet-130	1	17	&	&	CCONJ
admet-130	1	18	dmpk	dmpk	PROPN
admet-130	1	19	2(4	2(4	NUM
admet-130	1	20	)	)	PUNCT
admet-130	1	21	(	(	PUNCT
admet-130	1	22	2014	2014	NUM
admet-130	1	23	)	)	PUNCT
admet-130	1	24	272	272	NUM
admet-130	1	25	-	-	SYM
admet-130	1	26	281	281	NUM
admet-130	1	27	;	;	PUNCT
admet-130	1	28	doi	doi	NOUN
admet-130	1	29	:	:	PUNCT
admet-130	1	30	10.5599	10.5599	NUM
admet-130	1	31	/	/	SYM
admet-130	1	32	admet.2.4.130	admet.2.4.130	ADV
admet-130	1	33	open	open	ADJ
admet-130	1	34	access	access	NOUN
admet-130	1	35	:	:	PUNCT
admet-130	1	36	issn	issn	PROPN
admet-130	1	37	:	:	PUNCT
admet-130	1	38	1848	1848	NUM
admet-130	1	39	-	-	SYM
admet-130	1	40	7718	7718	NUM
admet-130	1	41	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-130	1	42	original	original	ADJ
admet-130	1	43	scientific	scientific	ADJ
admet-130	1	44	paper	paper	NOUN
admet-130	1	45	efficient	efficient	ADJ
admet-130	1	46	transdermal	transdermal	ADJ
admet-130	1	47	delivery	delivery	NOUN
admet-130	1	48	of	of	ADP
admet-130	1	49	benfotiamine	benfotiamine	ADJ
admet-130	1	50	in	in	ADP
admet-130	1	51	an	an	DET
admet-130	1	52	animal	animal	NOUN
admet-130	1	53	model	model	NOUN
admet-130	1	54	gyula	gyula	NOUN
admet-130	1	55	varadi	varadi	PROPN
admet-130	1	56	�	�	PROPN
admet-130	1	57	,	,	PUNCT
admet-130	1	58	zhen	zhen	PROPN
admet-130	1	59	zhu	zhu	PROPN
admet-130	1	60	and	and	CCONJ
admet-130	1	61	stephen	stephen	PROPN
admet-130	1	62	g.	g.	PROPN
admet-130	1	63	carter	carter	PROPN
admet-130	1	64	biochemics	biochemics	PROPN
admet-130	1	65	,	,	PUNCT
admet-130	1	66	inc	inc	PROPN
admet-130	1	67	.	.	PROPN
admet-130	1	68	,	,	PUNCT
admet-130	1	69	99	99	NUM
admet-130	1	70	rosewood	rosewood	NOUN
admet-130	1	71	drive	drive	NOUN
admet-130	1	72	,	,	PUNCT
admet-130	1	73	suite	suite	NOUN
admet-130	1	74	270	270	NUM
admet-130	1	75	,	,	PUNCT
admet-130	1	76	danvers	danver	NOUN
admet-130	1	77	,	,	PUNCT
admet-130	1	78	ma	ma	PROPN
admet-130	1	79	01923	01923	NUM
admet-130	1	80	-	-	SYM
admet-130	1	81	4537	4537	NUM
admet-130	1	82	,	,	PUNCT
admet-130	1	83	usa	usa	PROPN
admet-130	1	84	�	�	PROPN
admet-130	1	85	corresponding	corresponding	ADJ
admet-130	1	86	author	author	NOUN
admet-130	1	87	:	:	PUNCT
admet-130	1	88	gyula	gyula	NOUN
admet-130	1	89	varadi	varadi	NOUN
admet-130	1	90	,	,	PUNCT
admet-130	1	91	e	e	NOUN
admet-130	1	92	-	-	NOUN
admet-130	1	93	mail	mail	NOUN
admet-130	1	94	:	:	PUNCT
admet-130	2	1	gvaradi@biochemics.com	gvaradi@biochemics.com	NOUN
admet-130	2	2	;	;	PUNCT
admet-130	2	3	tel	tel	PROPN
admet-130	2	4	.	.	PUNCT
admet-130	2	5	:	:	PUNCT
admet-130	3	1	+1	+1	PROPN
admet-130	3	2	-	-	PUNCT
admet-130	3	3	978	978	NUM
admet-130	3	4	-	-	PUNCT
admet-130	3	5	750	750	NUM
admet-130	3	6	-	-	PUNCT
admet-130	3	7	0090	0090	NUM
admet-130	3	8	;	;	PUNCT
admet-130	3	9	fax	fax	NOUN
admet-130	3	10	:	:	PUNCT
admet-130	3	11	+1	+1	PROPN
admet-130	3	12	-	-	PUNCT
admet-130	3	13	978	978	NUM
admet-130	3	14	-	-	PUNCT
admet-130	3	15	7500080	7500080	NUM
admet-130	3	16	received	receive	VERB
admet-130	3	17	:	:	PUNCT
admet-130	3	18	november	november	PROPN
admet-130	3	19	13	13	NUM
admet-130	3	20	,	,	PUNCT
admet-130	3	21	2014	2014	NUM
admet-130	3	22	;	;	PUNCT
admet-130	3	23	revised	revise	VERB
admet-130	3	24	:	:	PUNCT
admet-130	3	25	december	december	PROPN
admet-130	3	26	13	13	NUM
admet-130	3	27	,	,	PUNCT
admet-130	3	28	2014	2014	NUM
admet-130	3	29	;	;	PUNCT
admet-130	3	30	published	publish	VERB
admet-130	3	31	:	:	PUNCT
admet-130	3	32	january	january	PROPN
admet-130	3	33	09	09	NUM
admet-130	3	34	,	,	PUNCT
admet-130	3	35	2015	2015	NUM
admet-130	3	36	abstract	abstract	NOUN
admet-130	3	37	we	we	PRON
admet-130	3	38	designed	design	VERB
admet-130	3	39	a	a	DET
admet-130	3	40	transdermal	transdermal	ADJ
admet-130	3	41	system	system	NOUN
admet-130	3	42	to	to	PART
admet-130	3	43	serve	serve	VERB
admet-130	3	44	as	as	ADP
admet-130	3	45	a	a	DET
admet-130	3	46	delivery	delivery	NOUN
admet-130	3	47	platform	platform	NOUN
admet-130	3	48	for	for	ADP
admet-130	3	49	benfotiamine	benfotiamine	ADJ
admet-130	3	50	utilizing	utilize	VERB
admet-130	3	51	the	the	DET
admet-130	3	52	attributes	attribute	NOUN
admet-130	3	53	of	of	ADP
admet-130	3	54	passive	passive	ADJ
admet-130	3	55	penetration	penetration	NOUN
admet-130	3	56	enhancing	enhance	VERB
admet-130	3	57	molecules	molecule	NOUN
admet-130	3	58	to	to	PART
admet-130	3	59	penetrate	penetrate	VERB
admet-130	3	60	through	through	ADP
admet-130	3	61	the	the	DET
admet-130	3	62	outer	outer	ADJ
admet-130	3	63	layers	layer	NOUN
admet-130	3	64	of	of	ADP
admet-130	3	65	skin	skin	NOUN
admet-130	3	66	combined	combine	VERB
admet-130	3	67	with	with	ADP
admet-130	3	68	the	the	DET
admet-130	3	69	advance	advance	NOUN
admet-130	3	70	of	of	ADP
admet-130	3	71	incorporating	incorporate	VERB
admet-130	3	72	various	various	ADJ
admet-130	3	73	peripherally	peripherally	ADV
admet-130	3	74	-	-	PUNCT
admet-130	3	75	acting	act	VERB
admet-130	3	76	vasodilators	vasodilator	NOUN
admet-130	3	77	to	to	PART
admet-130	3	78	enhance	enhance	VERB
admet-130	3	79	drug	drug	NOUN
admet-130	3	80	uptake	uptake	NOUN
admet-130	3	81	.	.	PUNCT
admet-130	4	1	benfotiamine	benfotiamine	ADJ
admet-130	4	2	,	,	PUNCT
admet-130	4	3	incorporated	incorporate	VERB
admet-130	4	4	into	into	ADP
admet-130	4	5	this	this	DET
admet-130	4	6	transdermal	transdermal	ADJ
admet-130	4	7	formulation	formulation	NOUN
admet-130	4	8	,	,	PUNCT
admet-130	4	9	was	be	AUX
admet-130	4	10	applied	apply	VERB
admet-130	4	11	to	to	ADP
admet-130	4	12	skin	skin	NOUN
admet-130	4	13	in	in	ADP
admet-130	4	14	an	an	DET
admet-130	4	15	animal	animal	NOUN
admet-130	4	16	model	model	NOUN
admet-130	4	17	in	in	ADP
admet-130	4	18	order	order	NOUN
admet-130	4	19	to	to	PART
admet-130	4	20	determine	determine	VERB
admet-130	4	21	the	the	DET
admet-130	4	22	ability	ability	NOUN
admet-130	4	23	to	to	PART
admet-130	4	24	deliver	deliver	VERB
admet-130	4	25	this	this	DET
admet-130	4	26	thiamine	thiamine	NOUN
admet-130	4	27	pro	pro	ADJ
admet-130	4	28	-	-	ADJ
admet-130	4	29	drug	drug	ADJ
admet-130	4	30	effectively	effectively	ADV
admet-130	4	31	to	to	ADP
admet-130	4	32	the	the	DET
admet-130	4	33	sub	sub	ADJ
admet-130	4	34	-	-	ADJ
admet-130	4	35	epithelial	epithelial	ADJ
admet-130	4	36	layers	layer	NOUN
admet-130	4	37	.	.	PUNCT
admet-130	5	1	in	in	ADP
admet-130	5	2	this	this	DET
admet-130	5	3	proof	proof	NOUN
admet-130	5	4	of	of	ADP
admet-130	5	5	concept	concept	NOUN
admet-130	5	6	study	study	NOUN
admet-130	5	7	in	in	ADP
admet-130	5	8	guinea	guinea	NOUN
admet-130	5	9	pigs	pig	NOUN
admet-130	5	10	,	,	PUNCT
admet-130	5	11	we	we	PRON
admet-130	5	12	found	find	VERB
admet-130	5	13	that	that	SCONJ
admet-130	5	14	a	a	DET
admet-130	5	15	single	single	ADJ
admet-130	5	16	topical	topical	ADJ
admet-130	5	17	application	application	NOUN
admet-130	5	18	of	of	ADP
admet-130	5	19	either	either	CCONJ
admet-130	5	20	a	a	DET
admet-130	5	21	solubilized	solubilize	VERB
admet-130	5	22	form	form	NOUN
admet-130	5	23	of	of	ADP
admet-130	5	24	benfotiamine	benfotiamine	ADJ
admet-130	5	25	(	(	PUNCT
admet-130	5	26	15	15	NUM
admet-130	5	27	mg	mg	NOUN
admet-130	5	28	)	)	PUNCT
admet-130	5	29	or	or	CCONJ
admet-130	5	30	a	a	DET
admet-130	5	31	microcrystalline	microcrystalline	NOUN
admet-130	5	32	suspension	suspension	NOUN
admet-130	5	33	form	form	NOUN
admet-130	5	34	(	(	PUNCT
admet-130	5	35	25	25	NUM
admet-130	5	36	mg	mg	NOUN
admet-130	5	37	)	)	PUNCT
admet-130	5	38	resulted	result	VERB
admet-130	5	39	in	in	ADP
admet-130	5	40	considerable	considerable	ADJ
admet-130	5	41	increases	increase	NOUN
admet-130	5	42	of	of	ADP
admet-130	5	43	the	the	DET
admet-130	5	44	dephosphorylated	dephosphorylate	VERB
admet-130	5	45	benfotiamine	benfotiamine	ADJ
admet-130	5	46	(	(	PUNCT
admet-130	5	47	s	s	NOUN
admet-130	5	48	-	-	NOUN
admet-130	5	49	benzoylthiamine	benzoylthiamine	NOUN
admet-130	5	50	)	)	PUNCT
admet-130	5	51	in	in	ADP
admet-130	5	52	the	the	DET
admet-130	5	53	skin	skin	NOUN
admet-130	5	54	tissue	tissue	NOUN
admet-130	5	55	as	as	ADV
admet-130	5	56	well	well	ADV
admet-130	5	57	as	as	ADP
admet-130	5	58	in	in	ADP
admet-130	5	59	significant	significant	ADJ
admet-130	5	60	increases	increase	NOUN
admet-130	5	61	in	in	ADP
admet-130	5	62	the	the	DET
admet-130	5	63	thiamine	thiamine	NOUN
admet-130	5	64	and	and	CCONJ
admet-130	5	65	thiamine	thiamine	NOUN
admet-130	5	66	phosphate	phosphate	NOUN
admet-130	5	67	pools	pool	NOUN
admet-130	5	68	compared	compare	VERB
admet-130	5	69	to	to	ADP
admet-130	5	70	control	control	VERB
admet-130	5	71	animals	animal	NOUN
admet-130	5	72	.	.	PUNCT
admet-130	6	1	the	the	DET
admet-130	6	2	presence	presence	NOUN
admet-130	6	3	of	of	ADP
admet-130	6	4	a	a	DET
admet-130	6	5	~8000x	~8000x	ADJ
admet-130	6	6	increase	increase	NOUN
admet-130	6	7	in	in	ADP
admet-130	6	8	thiamine	thiamine	NOUN
admet-130	6	9	and	and	CCONJ
admet-130	6	10	increases	increase	NOUN
admet-130	6	11	in	in	ADP
admet-130	6	12	its	its	PRON
admet-130	6	13	phosphorylated	phosphorylate	VERB
admet-130	6	14	derivatives	derivative	NOUN
admet-130	6	15	in	in	ADP
admet-130	6	16	the	the	DET
admet-130	6	17	epidermis	epidermis	NOUN
admet-130	6	18	and	and	CCONJ
admet-130	6	19	dermis	dermis	NOUN
admet-130	6	20	tissue	tissue	NOUN
admet-130	6	21	of	of	ADP
admet-130	6	22	the	the	DET
admet-130	6	23	test	test	NOUN
admet-130	6	24	animals	animal	NOUN
admet-130	6	25	gives	give	VERB
admet-130	6	26	a	a	DET
admet-130	6	27	strong	strong	ADJ
admet-130	6	28	indication	indication	NOUN
admet-130	6	29	that	that	SCONJ
admet-130	6	30	the	the	DET
admet-130	6	31	topical	topical	ADJ
admet-130	6	32	treatment	treatment	NOUN
admet-130	6	33	with	with	ADP
admet-130	6	34	benfotiamine	benfotiamine	ADJ
admet-130	6	35	works	work	NOUN
admet-130	6	36	very	very	ADV
admet-130	6	37	well	well	ADV
admet-130	6	38	for	for	ADP
admet-130	6	39	the	the	DET
admet-130	6	40	desired	desire	VERB
admet-130	6	41	outcome	outcome	NOUN
admet-130	6	42	of	of	ADP
admet-130	6	43	producing	produce	VERB
admet-130	6	44	an	an	DET
admet-130	6	45	intracellular	intracellular	ADJ
admet-130	6	46	increase	increase	NOUN
admet-130	6	47	of	of	ADP
admet-130	6	48	the	the	DET
admet-130	6	49	activating	activating	ADJ
admet-130	6	50	cofactor	cofactor	NOUN
admet-130	6	51	pool	pool	NOUN
admet-130	6	52	for	for	ADP
admet-130	6	53	transketolase	transketolase	NOUN
admet-130	6	54	enzyme	enzyme	NOUN
admet-130	6	55	,	,	PUNCT
admet-130	6	56	which	which	PRON
admet-130	6	57	is	be	AUX
admet-130	6	58	implicated	implicate	VERB
admet-130	6	59	in	in	ADP
admet-130	6	60	the	the	DET
admet-130	6	61	pathophysiology	pathophysiology	NOUN
admet-130	6	62	of	of	ADP
admet-130	6	63	diabetic	diabetic	NOUN
admet-130	6	64	neuropathy	neuropathy	ADJ
admet-130	6	65	.	.	PUNCT
admet-130	7	1	keywords	keyword	NOUN
admet-130	7	2	transdermal	transdermal	ADJ
admet-130	7	3	drug	drug	NOUN
admet-130	7	4	delivery	delivery	NOUN
admet-130	7	5	;	;	PUNCT
admet-130	7	6	benfotiamine	benfotiamine	ADJ
admet-130	7	7	;	;	PUNCT
admet-130	7	8	solubilized	solubilize	VERB
admet-130	7	9	benfotiamine	benfotiamine	ADJ
admet-130	7	10	;	;	PUNCT
admet-130	7	11	microcrystalline	microcrystalline	NOUN
admet-130	7	12	benfotiamine	benfotiamine	ADJ
admet-130	7	13	cream	cream	NOUN
admet-130	7	14	;	;	PUNCT
admet-130	7	15	thiamine	thiamine	NOUN
admet-130	7	16	,	,	PUNCT
admet-130	7	17	pentose	pentose	NOUN
admet-130	7	18	phosphate	phosphate	NOUN
admet-130	7	19	cycle	cycle	NOUN
admet-130	7	20	,	,	PUNCT
admet-130	7	21	pharmacokinetics	pharmacokinetic	NOUN
admet-130	7	22	;	;	PUNCT
admet-130	7	23	diabetic	diabetic	ADJ
admet-130	7	24	peripheral	peripheral	ADJ
admet-130	7	25	neuropathy	neuropathy	ADJ
admet-130	7	26	introduction	introduction	NOUN
admet-130	7	27	in	in	ADP
admet-130	7	28	diabetic	diabetic	ADJ
admet-130	7	29	conditions	condition	NOUN
admet-130	7	30	,	,	PUNCT
admet-130	7	31	hyperglycemia	hyperglycemia	NOUN
admet-130	7	32	induces	induce	VERB
admet-130	7	33	an	an	DET
admet-130	7	34	altered	altered	ADJ
admet-130	7	35	cellular	cellular	ADJ
admet-130	7	36	metabolism	metabolism	NOUN
admet-130	7	37	,	,	PUNCT
admet-130	7	38	and	and	CCONJ
admet-130	7	39	through	through	ADP
admet-130	7	40	a	a	DET
admet-130	7	41	series	series	NOUN
admet-130	7	42	of	of	ADP
admet-130	7	43	events	event	NOUN
admet-130	7	44	results	result	NOUN
admet-130	7	45	in	in	ADP
admet-130	7	46	the	the	DET
admet-130	7	47	creation	creation	NOUN
admet-130	7	48	of	of	ADP
admet-130	7	49	damaging	damage	VERB
admet-130	7	50	cellular	cellular	ADJ
admet-130	7	51	metabolites	metabolite	NOUN
admet-130	7	52	by	by	ADP
admet-130	7	53	influencing	influence	VERB
admet-130	7	54	a	a	DET
admet-130	7	55	number	number	NOUN
admet-130	7	56	of	of	ADP
admet-130	7	57	glucose	glucose	NOUN
admet-130	7	58	metabolizing	metabolize	VERB
admet-130	7	59	pathways	pathway	NOUN
admet-130	8	1	[	[	X
admet-130	8	2	1,2	1,2	NUM
admet-130	8	3	]	]	PUNCT
admet-130	8	4	.	.	PUNCT
admet-130	9	1	elevated	elevated	ADJ
admet-130	9	2	glucose	glucose	NOUN
admet-130	9	3	level	level	NOUN
admet-130	9	4	increases	increase	VERB
admet-130	9	5	the	the	DET
admet-130	9	6	metabolism	metabolism	NOUN
admet-130	9	7	through	through	ADP
admet-130	9	8	the	the	DET
admet-130	9	9	polyol	polyol	NOUN
admet-130	9	10	pathway	pathway	NOUN
admet-130	9	11	;	;	PUNCT
admet-130	9	12	increases	increase	VERB
admet-130	9	13	fructose-6	fructose-6	NOUN
admet-130	9	14	-	-	ADJ
admet-130	9	15	phosphate	phosphate	ADJ
admet-130	9	16	and	and	CCONJ
admet-130	9	17	glyceraldehyde-3	glyceraldehyde-3	NUM
admet-130	9	18	-	-	ADJ
admet-130	9	19	phosphate	phosphate	ADJ
admet-130	9	20	levels	level	NOUN
admet-130	9	21	,	,	PUNCT
admet-130	9	22	which	which	PRON
admet-130	9	23	latter	latter	ADV
admet-130	9	24	in	in	ADP
admet-130	9	25	turn	turn	NOUN
admet-130	9	26	increases	increase	VERB
admet-130	9	27	the	the	DET
admet-130	9	28	use	use	NOUN
admet-130	9	29	of	of	ADP
admet-130	9	30	the	the	DET
admet-130	9	31	diacylglycerol	diacylglycerol	NOUN
admet-130	9	32	pathway	pathway	NOUN
admet-130	9	33	leading	lead	VERB
admet-130	9	34	to	to	ADP
admet-130	9	35	an	an	DET
admet-130	9	36	increase	increase	NOUN
admet-130	9	37	in	in	ADP
admet-130	9	38	protein	protein	NOUN
admet-130	9	39	kinase	kinase	NOUN
admet-130	9	40	c	c	PROPN
admet-130	9	41	pathway	pathway	NOUN
admet-130	9	42	;	;	PUNCT
admet-130	9	43	increases	increase	VERB
admet-130	9	44	the	the	DET
admet-130	9	45	production	production	NOUN
admet-130	9	46	of	of	ADP
admet-130	9	47	superoxide	superoxide	NOUN
admet-130	9	48	molecules	molecule	NOUN
admet-130	9	49	and	and	CCONJ
admet-130	9	50	results	result	NOUN
admet-130	9	51	in	in	ADP
admet-130	9	52	increased	increase	VERB
admet-130	9	53	production	production	NOUN
admet-130	9	54	of	of	ADP
admet-130	9	55	advanced	advanced	ADJ
admet-130	9	56	glycation	glycation	NOUN
admet-130	9	57	endproducts	endproduct	NOUN
admet-130	9	58	(	(	PUNCT
admet-130	9	59	ages	age	NOUN
admet-130	9	60	)	)	PUNCT
admet-130	10	1	[	[	X
admet-130	10	2	2	2	NUM
admet-130	10	3	]	]	PUNCT
admet-130	10	4	,	,	PUNCT
admet-130	10	5	a	a	DET
admet-130	10	6	biochemical	biochemical	ADJ
admet-130	10	7	problem	problem	NOUN
admet-130	10	8	known	know	VERB
admet-130	10	9	to	to	PART
admet-130	10	10	be	be	AUX
admet-130	10	11	affected	affect	VERB
admet-130	10	12	in	in	ADP
admet-130	10	13	neuropathy	neuropathy	ADJ
admet-130	10	14	.	.	PUNCT
admet-130	11	1	ages	age	NOUN
admet-130	11	2	inhibit	inhibit	VERB
admet-130	11	3	key	key	ADJ
admet-130	11	4	cellular	cellular	ADJ
admet-130	11	5	proteins	protein	NOUN
admet-130	11	6	from	from	ADP
admet-130	11	7	functioning	function	VERB
admet-130	11	8	properly	properly	ADV
admet-130	11	9	[	[	X
admet-130	11	10	2	2	NUM
admet-130	11	11	-	-	SYM
admet-130	11	12	4	4	NUM
admet-130	11	13	]	]	PUNCT
admet-130	11	14	.	.	PUNCT
admet-130	12	1	in	in	ADP
admet-130	12	2	addition	addition	NOUN
admet-130	12	3	,	,	PUNCT
admet-130	12	4	ages	age	NOUN
admet-130	12	5	have	have	AUX
admet-130	12	6	been	be	AUX
admet-130	12	7	implicated	implicate	VERB
admet-130	12	8	in	in	ADP
admet-130	12	9	the	the	DET
admet-130	12	10	induction	induction	NOUN
admet-130	12	11	of	of	ADP
admet-130	12	12	admet	admet	PROPN
admet-130	12	13	&	&	CCONJ
admet-130	12	14	dmpk	dmpk	PROPN
admet-130	12	15	2(4	2(4	NUM
admet-130	12	16	)	)	PUNCT
admet-130	12	17	(	(	PUNCT
admet-130	12	18	2014	2014	NUM
admet-130	12	19	)	)	PUNCT
admet-130	12	20	272	272	NUM
admet-130	12	21	-	-	SYM
admet-130	12	22	281	281	NUM
admet-130	12	23	transderamal	transderamal	ADJ
admet-130	12	24	delivery	delivery	NOUN
admet-130	12	25	of	of	ADP
admet-130	12	26	benfotiamine	benfotiamine	ADJ
admet-130	12	27	in	in	ADP
admet-130	12	28	an	an	DET
admet-130	12	29	animal	animal	NOUN
admet-130	12	30	model	model	NOUN
admet-130	12	31	doi	doi	NOUN
admet-130	12	32	:	:	PUNCT
admet-130	12	33	10.5599	10.5599	NUM
admet-130	12	34	/	/	SYM
admet-130	12	35	admet.2.4.130	admet.2.4.130	ADP
admet-130	12	36	273	273	NUM
admet-130	12	37	apoptosis	apoptosis	NOUN
admet-130	12	38	,	,	PUNCT
admet-130	12	39	including	include	VERB
admet-130	12	40	peripheral	peripheral	ADJ
admet-130	12	41	nerve	nerve	NOUN
admet-130	12	42	cells	cell	NOUN
admet-130	12	43	resulting	result	VERB
admet-130	12	44	eventually	eventually	ADV
admet-130	12	45	in	in	ADP
admet-130	12	46	the	the	DET
admet-130	12	47	loss	loss	NOUN
admet-130	12	48	of	of	ADP
admet-130	12	49	sensation	sensation	NOUN
admet-130	12	50	to	to	ADP
admet-130	12	51	the	the	DET
admet-130	12	52	affected	affected	ADJ
admet-130	12	53	area	area	NOUN
admet-130	12	54	and	and	CCONJ
admet-130	12	55	in	in	ADP
admet-130	12	56	an	an	DET
admet-130	12	57	altered	altered	ADJ
admet-130	12	58	neuronal	neuronal	ADJ
admet-130	12	59	signaling	signal	VERB
admet-130	12	60	process	process	NOUN
admet-130	12	61	,	,	PUNCT
admet-130	12	62	which	which	PRON
admet-130	12	63	may	may	AUX
admet-130	12	64	present	present	VERB
admet-130	12	65	as	as	ADP
admet-130	12	66	pain	pain	NOUN
admet-130	12	67	[	[	X
admet-130	12	68	1,2,5	1,2,5	NUM
admet-130	12	69	]	]	PUNCT
admet-130	12	70	.	.	PUNCT
admet-130	13	1	there	there	PRON
admet-130	13	2	are	be	VERB
admet-130	13	3	many	many	ADJ
admet-130	13	4	candidate	candidate	NOUN
admet-130	13	5	molecular	molecular	ADJ
admet-130	13	6	targets	target	NOUN
admet-130	13	7	for	for	ADP
admet-130	13	8	the	the	DET
admet-130	13	9	treatment	treatment	NOUN
admet-130	13	10	of	of	ADP
admet-130	13	11	diabetic	diabetic	ADJ
admet-130	13	12	neuropathy	neuropathy	ADJ
admet-130	13	13	[	[	X
admet-130	13	14	6	6	NUM
admet-130	13	15	-	-	SYM
admet-130	13	16	8	8	NUM
admet-130	13	17	]	]	PUNCT
admet-130	13	18	.	.	PUNCT
admet-130	14	1	several	several	ADJ
admet-130	14	2	have	have	AUX
admet-130	14	3	been	be	AUX
admet-130	14	4	addressed	address	VERB
admet-130	14	5	through	through	ADP
admet-130	14	6	clinical	clinical	ADJ
admet-130	14	7	trial	trial	NOUN
admet-130	14	8	evaluations	evaluation	NOUN
admet-130	14	9	[	[	X
admet-130	14	10	8	8	NUM
admet-130	14	11	]	]	PUNCT
admet-130	14	12	and	and	CCONJ
admet-130	14	13	most	most	ADJ
admet-130	14	14	have	have	AUX
admet-130	14	15	failed	fail	VERB
admet-130	14	16	[	[	PUNCT
admet-130	14	17	9	9	NUM
admet-130	14	18	]	]	PUNCT
admet-130	14	19	.	.	PUNCT
admet-130	15	1	one	one	NUM
admet-130	15	2	of	of	ADP
admet-130	15	3	the	the	DET
admet-130	15	4	most	most	ADV
admet-130	15	5	considered	consider	VERB
admet-130	15	6	endpoints	endpoint	NOUN
admet-130	15	7	for	for	ADP
admet-130	15	8	the	the	DET
admet-130	15	9	development	development	NOUN
admet-130	15	10	of	of	ADP
admet-130	15	11	a	a	DET
admet-130	15	12	therapeutic	therapeutic	NOUN
admet-130	15	13	for	for	ADP
admet-130	15	14	this	this	DET
admet-130	15	15	diabetic	diabetic	ADJ
admet-130	15	16	complication	complication	NOUN
admet-130	15	17	is	be	AUX
admet-130	15	18	the	the	DET
admet-130	15	19	treatment	treatment	NOUN
admet-130	15	20	of	of	ADP
admet-130	15	21	pain	pain	NOUN
admet-130	15	22	associated	associate	VERB
admet-130	15	23	with	with	ADP
admet-130	15	24	the	the	DET
admet-130	15	25	neuronal	neuronal	ADJ
admet-130	15	26	deterioration	deterioration	NOUN
admet-130	15	27	.	.	PUNCT
admet-130	16	1	as	as	ADP
admet-130	16	2	a	a	DET
admet-130	16	3	result	result	NOUN
admet-130	16	4	,	,	PUNCT
admet-130	16	5	there	there	PRON
admet-130	16	6	have	have	AUX
admet-130	16	7	been	be	AUX
admet-130	16	8	several	several	ADJ
admet-130	16	9	candidate	candidate	NOUN
admet-130	16	10	therapies	therapy	NOUN
admet-130	16	11	using	use	VERB
admet-130	16	12	oral	oral	ADV
admet-130	16	13	and	and	CCONJ
admet-130	16	14	topically	topically	ADV
admet-130	16	15	applied	apply	VERB
admet-130	16	16	pain	pain	NOUN
admet-130	16	17	relievers	reliever	NOUN
admet-130	16	18	ranging	range	VERB
admet-130	16	19	from	from	ADP
admet-130	16	20	pregabalin	pregabalin	NOUN
admet-130	16	21	[	[	X
admet-130	16	22	10,11	10,11	NOUN
admet-130	16	23	]	]	PUNCT
admet-130	16	24	to	to	ADP
admet-130	16	25	capsaicin	capsaicin	NOUN
admet-130	16	26	[	[	X
admet-130	16	27	12	12	NUM
admet-130	16	28	]	]	PUNCT
admet-130	16	29	.	.	PUNCT
admet-130	17	1	apparently	apparently	ADV
admet-130	17	2	,	,	PUNCT
admet-130	17	3	in	in	ADP
admet-130	17	4	both	both	DET
admet-130	17	5	forms	form	NOUN
admet-130	17	6	(	(	PUNCT
admet-130	17	7	type	type	NOUN
admet-130	17	8	1	1	NUM
admet-130	17	9	and	and	CCONJ
admet-130	17	10	type	type	NOUN
admet-130	17	11	2	2	NUM
admet-130	17	12	)	)	PUNCT
admet-130	17	13	of	of	ADP
admet-130	17	14	diabetic	diabetic	ADJ
admet-130	17	15	condition	condition	NOUN
admet-130	17	16	there	there	PRON
admet-130	17	17	is	be	VERB
admet-130	17	18	about	about	ADV
admet-130	17	19	70	70	NUM
admet-130	17	20	%	%	NOUN
admet-130	17	21	thiamine	thiamine	NOUN
admet-130	17	22	deficiency	deficiency	NOUN
admet-130	17	23	as	as	SCONJ
admet-130	17	24	measured	measure	VERB
admet-130	17	25	in	in	ADP
admet-130	17	26	the	the	DET
admet-130	17	27	plasma	plasma	NOUN
admet-130	17	28	of	of	ADP
admet-130	17	29	diabetic	diabetic	ADJ
admet-130	17	30	patients	patient	NOUN
admet-130	17	31	[	[	X
admet-130	17	32	13	13	NUM
admet-130	17	33	-	-	SYM
admet-130	17	34	15	15	NUM
admet-130	17	35	]	]	PUNCT
admet-130	17	36	but	but	CCONJ
admet-130	17	37	the	the	DET
admet-130	17	38	physiological	physiological	ADJ
admet-130	17	39	mechanism	mechanism	NOUN
admet-130	17	40	associated	associate	VERB
admet-130	17	41	with	with	ADP
admet-130	17	42	this	this	DET
admet-130	17	43	deficiency	deficiency	NOUN
admet-130	17	44	has	have	AUX
admet-130	17	45	not	not	PART
admet-130	17	46	been	be	AUX
admet-130	17	47	clarified	clarify	VERB
admet-130	17	48	yet	yet	ADV
admet-130	17	49	.	.	PUNCT
admet-130	18	1	however	however	ADV
admet-130	18	2	,	,	PUNCT
admet-130	18	3	a	a	DET
admet-130	18	4	number	number	NOUN
admet-130	18	5	of	of	ADP
admet-130	18	6	studies	study	NOUN
admet-130	18	7	found	find	VERB
admet-130	18	8	an	an	DET
admet-130	18	9	altered	altered	ADJ
admet-130	18	10	thiamine	thiamine	NOUN
admet-130	18	11	handling	handling	NOUN
admet-130	18	12	in	in	ADP
admet-130	18	13	the	the	DET
admet-130	18	14	kidneys	kidney	NOUN
admet-130	18	15	of	of	ADP
admet-130	18	16	diabetic	diabetic	ADJ
admet-130	18	17	patients	patient	NOUN
admet-130	18	18	[	[	X
admet-130	18	19	16	16	NUM
admet-130	18	20	-	-	SYM
admet-130	18	21	18	18	NUM
admet-130	18	22	]	]	PUNCT
admet-130	18	23	.	.	PUNCT
admet-130	19	1	benfotiamine	benfotiamine	ADJ
admet-130	19	2	,	,	PUNCT
admet-130	19	3	(	(	PUNCT
admet-130	19	4	s	s	NOUN
admet-130	19	5	-	-	PUNCT
admet-130	19	6	benzoylthiamine	benzoylthiamine	NOUN
admet-130	19	7	-	-	PUNCT
admet-130	19	8	omonophosphate	omonophosphate	NOUN
admet-130	19	9	)	)	PUNCT
admet-130	19	10	,	,	PUNCT
admet-130	19	11	a	a	DET
admet-130	19	12	derivative	derivative	NOUN
admet-130	19	13	of	of	ADP
admet-130	19	14	the	the	DET
admet-130	19	15	vitamin	vitamin	NOUN
admet-130	19	16	b1	b1	NOUN
admet-130	19	17	or	or	CCONJ
admet-130	19	18	thiamine	thiamine	NOUN
admet-130	19	19	,	,	PUNCT
admet-130	19	20	has	have	VERB
admet-130	19	21	a	a	DET
admet-130	19	22	much	much	ADV
admet-130	19	23	higher	high	ADJ
admet-130	19	24	bioavailability	bioavailability	NOUN
admet-130	19	25	than	than	ADP
admet-130	19	26	thiamine	thiamine	NOUN
admet-130	19	27	and	and	CCONJ
admet-130	19	28	,	,	PUNCT
admet-130	19	29	as	as	ADP
admet-130	19	30	a	a	DET
admet-130	19	31	result	result	NOUN
admet-130	19	32	,	,	PUNCT
admet-130	19	33	accumulates	accumulate	VERB
admet-130	19	34	in	in	ADP
admet-130	19	35	the	the	DET
admet-130	19	36	target	target	NOUN
admet-130	19	37	tissues	tissue	NOUN
admet-130	19	38	much	much	ADV
admet-130	19	39	more	more	ADJ
admet-130	19	40	than	than	ADP
admet-130	19	41	thiamine	thiamine	VERB
admet-130	19	42	itself	itself	PRON
admet-130	20	1	[	[	X
admet-130	20	2	15,19,20	15,19,20	NUM
admet-130	20	3	]	]	PUNCT
admet-130	21	1	.	.	PUNCT
admet-130	22	1	thiamine	thiamine	NOUN
admet-130	22	2	absorption	absorption	NOUN
admet-130	22	3	from	from	ADP
admet-130	22	4	oral	oral	ADJ
admet-130	22	5	benfotiamine	benfotiamine	NOUN
admet-130	22	6	is	be	AUX
admet-130	22	7	approximately	approximately	ADV
admet-130	22	8	five	five	NUM
admet-130	22	9	times	time	NOUN
admet-130	22	10	greater	great	ADJ
admet-130	22	11	than	than	ADP
admet-130	22	12	from	from	ADP
admet-130	22	13	conventional	conventional	ADJ
admet-130	22	14	thiamine	thiamine	NOUN
admet-130	22	15	supplements	supplement	NOUN
admet-130	22	16	[	[	X
admet-130	22	17	21	21	NUM
admet-130	22	18	-	-	SYM
admet-130	22	19	23	23	NUM
admet-130	22	20	]	]	PUNCT
admet-130	22	21	.	.	PUNCT
admet-130	23	1	once	once	SCONJ
admet-130	23	2	benfotiamine	benfotiamine	PROPN
admet-130	23	3	has	have	AUX
admet-130	23	4	been	be	AUX
admet-130	23	5	transported	transport	VERB
admet-130	23	6	to	to	ADP
admet-130	23	7	the	the	DET
admet-130	23	8	target	target	NOUN
admet-130	23	9	tissue	tissue	NOUN
admet-130	23	10	,	,	PUNCT
admet-130	23	11	it	it	PRON
admet-130	23	12	is	be	AUX
admet-130	23	13	converted	convert	VERB
admet-130	23	14	through	through	ADP
admet-130	23	15	a	a	DET
admet-130	23	16	series	series	NOUN
admet-130	23	17	of	of	ADP
admet-130	23	18	metabolic	metabolic	NOUN
admet-130	23	19	and	and	CCONJ
admet-130	23	20	enzymatic	enzymatic	ADJ
admet-130	23	21	steps	step	NOUN
admet-130	23	22	to	to	ADP
admet-130	23	23	s	s	NOUN
admet-130	23	24	-	-	PUNCT
admet-130	23	25	benzoylthiamine	benzoylthiamine	NOUN
admet-130	23	26	,	,	PUNCT
admet-130	23	27	which	which	PRON
admet-130	23	28	after	after	ADP
admet-130	23	29	internalization	internalization	NOUN
admet-130	23	30	into	into	ADP
admet-130	23	31	the	the	DET
admet-130	23	32	cell	cell	NOUN
admet-130	23	33	forms	form	NOUN
admet-130	23	34	thiamine	thiamine	NOUN
admet-130	23	35	.	.	PUNCT
admet-130	24	1	this	this	DET
admet-130	24	2	latter	latter	ADJ
admet-130	24	3	then	then	ADV
admet-130	24	4	serves	serve	VERB
admet-130	24	5	as	as	ADP
admet-130	24	6	a	a	DET
admet-130	24	7	substrate	substrate	NOUN
admet-130	24	8	for	for	ADP
admet-130	24	9	enzymatic	enzymatic	ADJ
admet-130	24	10	conversion	conversion	NOUN
admet-130	24	11	to	to	PART
admet-130	24	12	form	form	VERB
admet-130	24	13	thiamine	thiamine	NOUN
admet-130	24	14	mono-	mono-	X
admet-130	24	15	,	,	PUNCT
admet-130	24	16	di-	di-	PROPN
admet-130	24	17	,	,	PUNCT
admet-130	24	18	and	and	CCONJ
admet-130	24	19	triphosphates	triphosphate	NOUN
admet-130	24	20	.	.	PUNCT
admet-130	25	1	it	it	PRON
admet-130	25	2	is	be	AUX
admet-130	25	3	however	however	ADV
admet-130	25	4	the	the	DET
admet-130	25	5	thiamine	thiamine	NOUN
admet-130	25	6	diphosphate	diphosphate	NOUN
admet-130	25	7	(	(	PUNCT
admet-130	25	8	tdp	tdp	NOUN
admet-130	25	9	)	)	PUNCT
admet-130	25	10	that	that	PRON
admet-130	25	11	is	be	AUX
admet-130	25	12	responsible	responsible	ADJ
admet-130	25	13	for	for	ADP
admet-130	25	14	binding	bind	VERB
admet-130	25	15	to	to	ADP
admet-130	25	16	and	and	CCONJ
admet-130	25	17	activating	activate	VERB
admet-130	25	18	the	the	DET
admet-130	25	19	enzyme	enzyme	NOUN
admet-130	25	20	transketolase	transketolase	NOUN
admet-130	25	21	,	,	PUNCT
admet-130	25	22	a	a	DET
admet-130	25	23	critical	critical	ADJ
admet-130	25	24	enzyme	enzyme	NOUN
admet-130	25	25	for	for	ADP
admet-130	25	26	the	the	DET
admet-130	25	27	metabolism	metabolism	NOUN
admet-130	25	28	of	of	ADP
admet-130	25	29	the	the	DET
admet-130	25	30	hyperglycemic	hyperglycemic	ADJ
admet-130	25	31	by	by	ADP
admet-130	25	32	-	-	PUNCT
admet-130	25	33	products	product	NOUN
admet-130	25	34	via	via	ADP
admet-130	25	35	the	the	DET
admet-130	25	36	pentose	pentose	NOUN
admet-130	25	37	phosphate	phosphate	NOUN
admet-130	25	38	pathway	pathway	NOUN
admet-130	25	39	to	to	PART
admet-130	25	40	generate	generate	VERB
admet-130	25	41	metabolic	metabolic	NOUN
admet-130	25	42	products	product	NOUN
admet-130	25	43	that	that	PRON
admet-130	25	44	are	be	AUX
admet-130	25	45	not	not	PART
admet-130	25	46	damaging	damage	VERB
admet-130	25	47	to	to	ADP
admet-130	25	48	the	the	DET
admet-130	25	49	cells	cell	NOUN
admet-130	25	50	.	.	PUNCT
admet-130	26	1	benfotiamine	benfotiamine	PROPN
admet-130	26	2	was	be	AUX
admet-130	26	3	employed	employ	VERB
admet-130	26	4	to	to	PART
admet-130	26	5	treat	treat	VERB
admet-130	26	6	alcoholic	alcoholic	ADJ
admet-130	26	7	neuropathy	neuropathy	ADJ
admet-130	26	8	[	[	X
admet-130	26	9	24,25	24,25	NUM
admet-130	26	10	]	]	X
admet-130	26	11	sciatica	sciatica	NOUN
admet-130	26	12	and	and	CCONJ
admet-130	26	13	other	other	ADJ
admet-130	26	14	painful	painful	ADJ
admet-130	26	15	nerve	nerve	NOUN
admet-130	26	16	conditions	condition	NOUN
admet-130	26	17	[	[	X
admet-130	26	18	26,27	26,27	NUM
admet-130	26	19	]	]	PUNCT
admet-130	26	20	known	know	VERB
admet-130	26	21	to	to	PART
admet-130	26	22	be	be	AUX
admet-130	26	23	affected	affect	VERB
admet-130	26	24	with	with	ADP
admet-130	26	25	low	low	ADJ
admet-130	26	26	thiamine	thiamine	NOUN
admet-130	26	27	content	content	NOUN
admet-130	27	1	[	[	X
admet-130	27	2	28	28	NUM
admet-130	27	3	-	-	SYM
admet-130	27	4	30	30	NUM
admet-130	27	5	]	]	PUNCT
admet-130	27	6	.	.	PUNCT
admet-130	28	1	the	the	DET
admet-130	28	2	application	application	NOUN
admet-130	28	3	of	of	ADP
admet-130	28	4	benfotiamine	benfotiamine	ADJ
admet-130	28	5	and	and	CCONJ
admet-130	28	6	the	the	DET
admet-130	28	7	resulting	result	VERB
admet-130	28	8	activation	activation	NOUN
admet-130	28	9	of	of	ADP
admet-130	28	10	the	the	DET
admet-130	28	11	enzyme	enzyme	NOUN
admet-130	28	12	transketolase	transketolase	NOUN
admet-130	28	13	in	in	ADP
admet-130	28	14	the	the	DET
admet-130	28	15	diabetic	diabetic	NOUN
admet-130	28	16	,	,	PUNCT
admet-130	28	17	hyperglycemic	hyperglycemic	ADJ
admet-130	28	18	system	system	NOUN
admet-130	28	19	can	can	AUX
admet-130	28	20	also	also	ADV
admet-130	28	21	produce	produce	VERB
admet-130	28	22	beneficial	beneficial	ADJ
admet-130	28	23	effects	effect	NOUN
admet-130	28	24	on	on	ADP
admet-130	28	25	general	general	ADJ
admet-130	28	26	nerve	nerve	NOUN
admet-130	28	27	health	health	NOUN
admet-130	28	28	.	.	PUNCT
admet-130	29	1	benfotiamine	benfotiamine	PROPN
admet-130	29	2	has	have	AUX
admet-130	29	3	been	be	AUX
admet-130	29	4	shown	show	VERB
admet-130	29	5	in	in	ADP
admet-130	29	6	many	many	ADJ
admet-130	29	7	preclinical	preclinical	ADJ
admet-130	29	8	[	[	X
admet-130	29	9	21,31	21,31	NUM
admet-130	29	10	-	-	SYM
admet-130	29	11	43	43	NUM
admet-130	29	12	]	]	PUNCT
admet-130	29	13	as	as	ADV
admet-130	29	14	well	well	ADV
admet-130	29	15	as	as	ADP
admet-130	29	16	clinical	clinical	ADJ
admet-130	29	17	studies	study	NOUN
admet-130	29	18	[	[	X
admet-130	29	19	44	44	NUM
admet-130	29	20	-	-	SYM
admet-130	29	21	57	57	NUM
admet-130	29	22	]	]	PUNCT
admet-130	29	23	to	to	PART
admet-130	29	24	prevent	prevent	VERB
admet-130	29	25	the	the	DET
admet-130	29	26	formation	formation	NOUN
admet-130	29	27	of	of	ADP
admet-130	29	28	ages	age	NOUN
admet-130	29	29	[	[	X
admet-130	29	30	21,53	21,53	NOUN
admet-130	29	31	]	]	PUNCT
admet-130	29	32	and	and	CCONJ
admet-130	29	33	eventually	eventually	ADV
admet-130	29	34	with	with	ADP
admet-130	29	35	continued	continued	ADJ
admet-130	29	36	treatment	treatment	NOUN
admet-130	29	37	to	to	PART
admet-130	29	38	reverse	reverse	VERB
admet-130	29	39	the	the	DET
admet-130	29	40	symptoms	symptom	NOUN
admet-130	29	41	associated	associate	VERB
admet-130	29	42	with	with	ADP
admet-130	29	43	the	the	DET
admet-130	29	44	neuropathy	neuropathy	ADJ
admet-130	29	45	[	[	X
admet-130	29	46	46,47,52,57	46,47,52,57	NUM
admet-130	29	47	]	]	PUNCT
admet-130	29	48	.	.	PUNCT
admet-130	30	1	by	by	ADP
admet-130	30	2	increasing	increase	VERB
admet-130	30	3	intracellular	intracellular	ADJ
admet-130	30	4	levels	level	NOUN
admet-130	30	5	of	of	ADP
admet-130	30	6	thiamine	thiamine	NOUN
admet-130	30	7	,	,	PUNCT
admet-130	30	8	benfotiamine	benfotiamine	ADJ
admet-130	30	9	indirectly	indirectly	ADV
admet-130	30	10	induces	induce	VERB
admet-130	30	11	enzymatic	enzymatic	ADJ
admet-130	30	12	and	and	CCONJ
admet-130	30	13	biochemical	biochemical	ADJ
admet-130	30	14	pathways	pathway	NOUN
admet-130	31	1	[	[	X
admet-130	31	2	58	58	NUM
admet-130	31	3	-	-	SYM
admet-130	31	4	60	60	NUM
admet-130	31	5	]	]	PUNCT
admet-130	31	6	through	through	ADP
admet-130	31	7	elevated	elevated	ADJ
admet-130	31	8	concentrations	concentration	NOUN
admet-130	31	9	of	of	ADP
admet-130	31	10	thiamine	thiamine	NOUN
admet-130	31	11	diphosphate	diphosphate	NOUN
admet-130	31	12	resulting	result	VERB
admet-130	31	13	in	in	ADP
admet-130	31	14	a	a	DET
admet-130	31	15	reduced	reduced	ADJ
admet-130	31	16	level	level	NOUN
admet-130	31	17	of	of	ADP
admet-130	31	18	damaging	damage	VERB
admet-130	31	19	glucose	glucose	NOUN
admet-130	31	20	-	-	PUNCT
admet-130	31	21	derived	derive	VERB
admet-130	31	22	chemical	chemical	NOUN
admet-130	31	23	protein	protein	NOUN
admet-130	31	24	species	specie	NOUN
admet-130	32	1	[	[	X
admet-130	32	2	21,22,32,37	21,22,32,37	NUM
admet-130	32	3	-	-	PUNCT
admet-130	32	4	39,60	39,60	NUM
admet-130	32	5	-	-	PUNCT
admet-130	32	6	62	62	NUM
admet-130	32	7	]	]	PUNCT
admet-130	32	8	.	.	PUNCT
admet-130	33	1	benfotiamine	benfotiamine	PROPN
admet-130	33	2	is	be	AUX
admet-130	33	3	currently	currently	ADV
admet-130	33	4	offered	offer	VERB
admet-130	33	5	as	as	ADP
admet-130	33	6	a	a	DET
admet-130	33	7	prescriptive	prescriptive	ADJ
admet-130	33	8	drug	drug	NOUN
admet-130	33	9	for	for	ADP
admet-130	33	10	the	the	DET
admet-130	33	11	treatment	treatment	NOUN
admet-130	33	12	of	of	ADP
admet-130	33	13	diabetic	diabetic	NOUN
admet-130	33	14	neuropathy	neuropathy	ADJ
admet-130	33	15	in	in	ADP
admet-130	33	16	europe	europe	PROPN
admet-130	33	17	in	in	ADP
admet-130	33	18	an	an	DET
admet-130	33	19	oral	oral	ADJ
admet-130	33	20	form	form	NOUN
admet-130	33	21	.	.	PUNCT
admet-130	34	1	it	it	PRON
admet-130	34	2	is	be	AUX
admet-130	34	3	also	also	ADV
admet-130	34	4	available	available	ADJ
admet-130	34	5	for	for	ADP
admet-130	34	6	similar	similar	ADJ
admet-130	34	7	indications	indication	NOUN
admet-130	34	8	as	as	ADP
admet-130	34	9	a	a	DET
admet-130	34	10	homeopathic	homeopathic	ADJ
admet-130	34	11	medicine	medicine	NOUN
admet-130	34	12	and	and	CCONJ
admet-130	34	13	as	as	ADP
admet-130	34	14	a	a	DET
admet-130	34	15	dietary	dietary	ADJ
admet-130	34	16	supplement	supplement	NOUN
admet-130	34	17	.	.	PUNCT
admet-130	35	1	the	the	DET
admet-130	35	2	typical	typical	ADJ
admet-130	35	3	oral	oral	ADJ
admet-130	35	4	dose	dose	NOUN
admet-130	35	5	recommended	recommend	VERB
admet-130	35	6	is	be	AUX
admet-130	35	7	40	40	NUM
admet-130	35	8	-	-	SYM
admet-130	35	9	450	450	NUM
admet-130	35	10	mg	mg	NUM
admet-130	35	11	/	/	SYM
admet-130	35	12	day	day	NOUN
admet-130	36	1	[	[	X
admet-130	36	2	63,64	63,64	NOUN
admet-130	36	3	]	]	X
admet-130	36	4	.	.	PUNCT
admet-130	37	1	the	the	DET
admet-130	37	2	topical	topical	ADJ
admet-130	37	3	application	application	NOUN
admet-130	37	4	of	of	ADP
admet-130	37	5	benfotiamine	benfotiamine	ADJ
admet-130	37	6	may	may	AUX
admet-130	37	7	allow	allow	VERB
admet-130	37	8	more	more	ADJ
admet-130	37	9	prodrug	prodrug	NOUN
admet-130	37	10	to	to	PART
admet-130	37	11	be	be	AUX
admet-130	37	12	introduced	introduce	VERB
admet-130	37	13	into	into	ADP
admet-130	37	14	the	the	DET
admet-130	37	15	target	target	NOUN
admet-130	37	16	tissues	tissue	NOUN
admet-130	37	17	and	and	CCONJ
admet-130	37	18	,	,	PUNCT
admet-130	37	19	as	as	ADP
admet-130	37	20	a	a	DET
admet-130	37	21	result	result	NOUN
admet-130	37	22	,	,	PUNCT
admet-130	37	23	potentially	potentially	ADV
admet-130	37	24	generate	generate	VERB
admet-130	37	25	a	a	DET
admet-130	37	26	greater	great	ADJ
admet-130	37	27	therapeutic	therapeutic	ADJ
admet-130	37	28	effect	effect	NOUN
admet-130	37	29	.	.	PUNCT
admet-130	38	1	experimental	experimental	ADJ
admet-130	38	2	we	we	PRON
admet-130	38	3	prepared	prepare	VERB
admet-130	38	4	two	two	NUM
admet-130	38	5	topical	topical	ADJ
admet-130	38	6	formulations	formulation	NOUN
admet-130	38	7	for	for	ADP
admet-130	38	8	these	these	DET
admet-130	38	9	studies	study	NOUN
admet-130	38	10	.	.	PUNCT
admet-130	39	1	the	the	DET
admet-130	39	2	topical	topical	ADJ
admet-130	39	3	formulation	formulation	NOUN
admet-130	39	4	termed	term	VERB
admet-130	39	5	as	as	SCONJ
admet-130	39	6	3	3	NUM
admet-130	39	7	%	%	NOUN
admet-130	39	8	benfotiamine	benfotiamine	PROPN
admet-130	39	9	was	be	AUX
admet-130	39	10	prepared	prepare	VERB
admet-130	39	11	according	accord	VERB
admet-130	39	12	to	to	ADP
admet-130	39	13	a	a	DET
admet-130	39	14	vale	vale	ADJ
admet-130	39	15	formulation	formulation	NOUN
admet-130	39	16	[	[	X
admet-130	39	17	65	65	NUM
admet-130	39	18	]	]	PUNCT
admet-130	39	19	and	and	CCONJ
admet-130	39	20	contained	contain	VERB
admet-130	39	21	3	3	NUM
admet-130	39	22	%	%	NOUN
admet-130	39	23	benfotiamine	benfotiamine	ADJ
admet-130	39	24	in	in	ADP
admet-130	39	25	soluble	soluble	ADJ
admet-130	39	26	form	form	NOUN
admet-130	39	27	,	,	PUNCT
admet-130	39	28	neutralized	neutralize	VERB
admet-130	39	29	with	with	ADP
admet-130	39	30	arginine	arginine	NOUN
admet-130	39	31	.	.	PUNCT
admet-130	40	1	the	the	DET
admet-130	40	2	5	5	NUM
admet-130	40	3	%	%	NOUN
admet-130	40	4	topical	topical	ADJ
admet-130	40	5	formulation	formulation	NOUN
admet-130	40	6	contained	contain	VERB
admet-130	40	7	5	5	NUM
admet-130	40	8	%	%	NOUN
admet-130	40	9	benfotiamine	benfotiamine	ADJ
admet-130	40	10	,	,	PUNCT
admet-130	40	11	also	also	ADV
admet-130	40	12	in	in	ADP
admet-130	40	13	a	a	DET
admet-130	40	14	vale	vale	ADJ
admet-130	40	15	formulation	formulation	NOUN
admet-130	40	16	,	,	PUNCT
admet-130	40	17	but	but	CCONJ
admet-130	40	18	in	in	ADP
admet-130	40	19	microcrystalline	microcrystalline	NOUN
admet-130	40	20	form	form	NOUN
admet-130	40	21	.	.	PUNCT
admet-130	41	1	the	the	DET
admet-130	41	2	stability	stability	NOUN
admet-130	41	3	of	of	ADP
admet-130	41	4	these	these	DET
admet-130	41	5	products	product	NOUN
admet-130	41	6	was	be	AUX
admet-130	41	7	tested	test	VERB
admet-130	41	8	after	after	ADP
admet-130	41	9	one	one	NUM
admet-130	41	10	year	year	NOUN
admet-130	41	11	storage	storage	NOUN
admet-130	41	12	at	at	ADP
admet-130	41	13	4	4	NUM
admet-130	41	14	°	°	NOUN
admet-130	41	15	c	c	NOUN
admet-130	41	16	and	and	CCONJ
admet-130	41	17	we	we	PRON
admet-130	41	18	found	find	VERB
admet-130	41	19	that	that	SCONJ
admet-130	41	20	89	89	NUM
admet-130	41	21	%	%	NOUN
admet-130	41	22	of	of	ADP
admet-130	41	23	benfotiamine	benfotiamine	PROPN
admet-130	41	24	was	be	AUX
admet-130	41	25	present	present	ADJ
admet-130	41	26	in	in	ADP
admet-130	41	27	the	the	DET
admet-130	41	28	active	active	ADJ
admet-130	41	29	chemical	chemical	NOUN
admet-130	41	30	form	form	NOUN
admet-130	41	31	.	.	PUNCT
admet-130	42	1	varadi	varadi	PROPN
admet-130	42	2	et.al	et.al	PROPN
admet-130	42	3	.	.	PUNCT
admet-130	43	1	admet	admet	PROPN
admet-130	43	2	&	&	CCONJ
admet-130	43	3	dmpk	dmpk	PROPN
admet-130	43	4	2(4	2(4	NUM
admet-130	43	5	)	)	PUNCT
admet-130	43	6	(	(	PUNCT
admet-130	43	7	2014	2014	NUM
admet-130	43	8	)	)	PUNCT
admet-130	43	9	272	272	NUM
admet-130	43	10	-	-	SYM
admet-130	43	11	281	281	NUM
admet-130	43	12	274	274	NUM
admet-130	43	13	we	we	PRON
admet-130	43	14	utilized	utilize	VERB
admet-130	43	15	male	male	NOUN
admet-130	43	16	hartley	hartley	PROPN
admet-130	43	17	guinea	guinea	NOUN
admet-130	43	18	pigs	pig	NOUN
admet-130	43	19	(	(	PUNCT
admet-130	43	20	ca	ca	NOUN
admet-130	43	21	.	.	NOUN
admet-130	44	1	250	250	NUM
admet-130	44	2	-	-	SYM
admet-130	44	3	300	300	NUM
admet-130	44	4	g	g	NOUN
admet-130	44	5	)	)	PUNCT
admet-130	44	6	for	for	ADP
admet-130	44	7	pharmacokinetic	pharmacokinetic	ADJ
admet-130	44	8	studies	study	NOUN
admet-130	44	9	with	with	ADP
admet-130	44	10	two	two	NUM
admet-130	44	11	topical	topical	ADJ
admet-130	44	12	benfotiamine	benfotiamine	ADJ
admet-130	44	13	formulations	formulation	NOUN
admet-130	44	14	.	.	PUNCT
admet-130	45	1	the	the	DET
admet-130	45	2	guinea	guinea	NOUN
admet-130	45	3	pigs	pig	NOUN
admet-130	45	4	fur	fur	NOUN
admet-130	45	5	was	be	AUX
admet-130	45	6	clipped	clip	VERB
admet-130	45	7	from	from	ADP
admet-130	45	8	their	their	PRON
admet-130	45	9	back	back	NOUN
admet-130	45	10	,	,	PUNCT
admet-130	45	11	and	and	CCONJ
admet-130	45	12	an	an	DET
admet-130	45	13	area	area	NOUN
admet-130	45	14	of	of	ADP
admet-130	45	15	4x4	4x4	NUM
admet-130	45	16	cm	cm	NOUN
admet-130	45	17	depilated	depilate	VERB
admet-130	45	18	with	with	ADP
admet-130	45	19	nair	nair	NOUN
admet-130	45	20	.	.	PUNCT
admet-130	46	1	after	after	ADP
admet-130	46	2	ca	ca	PROPN
admet-130	46	3	.	.	PUNCT
admet-130	46	4	24	24	NUM
admet-130	46	5	hours	hour	NOUN
admet-130	46	6	,	,	PUNCT
admet-130	46	7	0.5	0.5	NUM
admet-130	46	8	g	g	NOUN
admet-130	46	9	of	of	ADP
admet-130	46	10	test	test	NOUN
admet-130	46	11	formulation	formulation	NOUN
admet-130	46	12	was	be	AUX
admet-130	46	13	applied	apply	VERB
admet-130	46	14	to	to	ADP
admet-130	46	15	a	a	DET
admet-130	46	16	2x4	2x4	NUM
admet-130	46	17	cm	cm	NOUN
admet-130	46	18	area	area	NOUN
admet-130	46	19	.	.	PUNCT
admet-130	47	1	the	the	DET
admet-130	47	2	test	test	NOUN
admet-130	47	3	formulations	formulation	NOUN
admet-130	47	4	tested	test	VERB
admet-130	47	5	either	either	CCONJ
admet-130	47	6	contained	contain	VERB
admet-130	47	7	a	a	DET
admet-130	47	8	solubilized	solubilize	VERB
admet-130	47	9	topical	topical	ADJ
admet-130	47	10	benfotiamine	benfotiamine	NOUN
admet-130	47	11	(	(	PUNCT
admet-130	47	12	3	3	NUM
admet-130	47	13	%	%	NOUN
admet-130	47	14	)	)	PUNCT
admet-130	47	15	yielding	yield	VERB
admet-130	47	16	a	a	DET
admet-130	47	17	dose	dose	NOUN
admet-130	47	18	of	of	ADP
admet-130	47	19	15	15	NUM
admet-130	47	20	mg	mg	NOUN
admet-130	47	21	of	of	ADP
admet-130	47	22	benfotiamine	benfotiamine	ADJ
admet-130	47	23	or	or	CCONJ
admet-130	47	24	a	a	DET
admet-130	47	25	microcrystalline	microcrystalline	NOUN
admet-130	47	26	suspension	suspension	NOUN
admet-130	47	27	form	form	NOUN
admet-130	47	28	of	of	ADP
admet-130	47	29	benfotiamine	benfotiamine	ADJ
admet-130	47	30	(	(	PUNCT
admet-130	47	31	5	5	NUM
admet-130	47	32	%	%	NOUN
admet-130	47	33	)	)	PUNCT
admet-130	47	34	yielding	yield	VERB
admet-130	47	35	a	a	DET
admet-130	47	36	dose	dose	NOUN
admet-130	47	37	of	of	ADP
admet-130	47	38	25	25	NUM
admet-130	47	39	mg	mg	PROPN
admet-130	47	40	benfotiamine	benfotiamine	NOUN
admet-130	47	41	.	.	PUNCT
admet-130	48	1	at	at	ADP
admet-130	48	2	0.5	0.5	NUM
admet-130	48	3	,	,	PUNCT
admet-130	48	4	1	1	NUM
admet-130	48	5	,	,	PUNCT
admet-130	48	6	2	2	NUM
admet-130	48	7	,	,	PUNCT
admet-130	48	8	4	4	NUM
admet-130	48	9	,	,	PUNCT
admet-130	48	10	8	8	NUM
admet-130	48	11	and	and	CCONJ
admet-130	48	12	24	24	NUM
admet-130	48	13	hours	hour	NOUN
admet-130	48	14	after	after	ADP
admet-130	48	15	application	application	NOUN
admet-130	48	16	,	,	PUNCT
admet-130	48	17	groups	group	NOUN
admet-130	48	18	of	of	ADP
admet-130	48	19	5	5	NUM
admet-130	48	20	animals	animal	NOUN
admet-130	48	21	were	be	AUX
admet-130	48	22	anesthetized	anesthetize	VERB
admet-130	48	23	with	with	ADP
admet-130	48	24	isoflurane	isoflurane	NOUN
admet-130	48	25	and	and	CCONJ
admet-130	48	26	blood	blood	NOUN
admet-130	48	27	removed	remove	VERB
admet-130	48	28	by	by	ADP
admet-130	48	29	cardiac	cardiac	ADJ
admet-130	48	30	stick	stick	NOUN
admet-130	48	31	.	.	PUNCT
admet-130	49	1	one	one	NUM
admet-130	49	2	group	group	NOUN
admet-130	49	3	of	of	ADP
admet-130	49	4	5	5	NUM
admet-130	49	5	untreated	untreated	ADJ
admet-130	49	6	animals	animal	NOUN
admet-130	49	7	was	be	AUX
admet-130	49	8	anesthetized	anesthetize	VERB
admet-130	49	9	and	and	CCONJ
admet-130	49	10	blood	blood	NOUN
admet-130	49	11	removed	remove	VERB
admet-130	49	12	as	as	ADP
admet-130	49	13	vehicle	vehicle	NOUN
admet-130	49	14	control	control	NOUN
admet-130	49	15	.	.	PUNCT
admet-130	50	1	blood	blood	NOUN
admet-130	50	2	samples	sample	NOUN
admet-130	50	3	were	be	AUX
admet-130	50	4	directly	directly	ADV
admet-130	50	5	processed	process	VERB
admet-130	50	6	to	to	PART
admet-130	50	7	analyze	analyze	VERB
admet-130	50	8	benfotiamine	benfotiamine	ADJ
admet-130	50	9	,	,	PUNCT
admet-130	50	10	s	s	NOUN
admet-130	50	11	-	-	NOUN
admet-130	50	12	benzoylthiamine	benzoylthiamine	NOUN
admet-130	50	13	,	,	PUNCT
admet-130	50	14	thiamine	thiamine	NOUN
admet-130	50	15	and	and	CCONJ
admet-130	50	16	its	its	PRON
admet-130	50	17	derivatives	derivative	NOUN
admet-130	50	18	by	by	ADP
admet-130	50	19	hplc	hplc	NOUN
admet-130	50	20	[	[	X
admet-130	50	21	66	66	NUM
admet-130	50	22	-	-	SYM
admet-130	50	23	70	70	NUM
admet-130	50	24	]	]	PUNCT
admet-130	50	25	.	.	PUNCT
admet-130	51	1	the	the	DET
admet-130	51	2	skin	skin	NOUN
admet-130	51	3	below	below	ADP
admet-130	51	4	the	the	DET
admet-130	51	5	area	area	NOUN
admet-130	51	6	of	of	ADP
admet-130	51	7	topical	topical	ADJ
admet-130	51	8	application	application	NOUN
admet-130	51	9	on	on	ADP
admet-130	51	10	each	each	DET
admet-130	51	11	animal	animal	NOUN
admet-130	51	12	in	in	ADP
admet-130	51	13	the	the	DET
admet-130	51	14	24	24	NUM
admet-130	51	15	hour	hour	NOUN
admet-130	51	16	exposure	exposure	NOUN
admet-130	51	17	group	group	NOUN
admet-130	51	18	was	be	AUX
admet-130	51	19	cleaned	clean	VERB
admet-130	51	20	,	,	PUNCT
admet-130	51	21	rubbed	rub	VERB
admet-130	51	22	with	with	ADP
admet-130	51	23	alcohol	alcohol	NOUN
admet-130	51	24	,	,	PUNCT
admet-130	51	25	with	with	ADP
admet-130	51	26	the	the	DET
admet-130	51	27	intent	intent	NOUN
admet-130	51	28	to	to	PART
admet-130	51	29	remove	remove	VERB
admet-130	51	30	the	the	DET
admet-130	51	31	stratum	stratum	NOUN
admet-130	51	32	corneum	corneum	NOUN
admet-130	51	33	,	,	PUNCT
admet-130	51	34	excised	excise	VERB
admet-130	51	35	,	,	PUNCT
admet-130	51	36	weighed	weigh	VERB
admet-130	51	37	,	,	PUNCT
admet-130	51	38	homogenized	homogenize	VERB
admet-130	51	39	in	in	ADP
admet-130	51	40	phosphate	phosphate	ADJ
admet-130	51	41	buffered	buffer	VERB
admet-130	51	42	saline	saline	NOUN
admet-130	51	43	,	,	PUNCT
admet-130	51	44	centrifuged	centrifuge	VERB
admet-130	51	45	,	,	PUNCT
admet-130	51	46	and	and	CCONJ
admet-130	51	47	ca	ca	NOUN
admet-130	51	48	.	.	NOUN
admet-130	51	49	2	2	NUM
admet-130	51	50	ml	ml	NOUN
admet-130	51	51	extract	extract	NOUN
admet-130	51	52	processed	process	VERB
admet-130	51	53	for	for	ADP
admet-130	51	54	pharmacokinetic	pharmacokinetic	ADJ
admet-130	51	55	analyses	analysis	NOUN
admet-130	52	1	[	[	X
admet-130	52	2	66	66	NUM
admet-130	52	3	-	-	SYM
admet-130	52	4	70	70	NUM
admet-130	52	5	]	]	PUNCT
admet-130	52	6	.	.	PUNCT
admet-130	53	1	the	the	DET
admet-130	53	2	blood	blood	NOUN
admet-130	53	3	and	and	CCONJ
admet-130	53	4	the	the	DET
admet-130	53	5	homogenized	homogenized	ADJ
admet-130	53	6	skin	skin	NOUN
admet-130	53	7	tissue	tissue	NOUN
admet-130	53	8	were	be	AUX
admet-130	53	9	evaluated	evaluate	VERB
admet-130	53	10	at	at	ADP
admet-130	53	11	various	various	ADJ
admet-130	53	12	time	time	NOUN
admet-130	53	13	points	point	NOUN
admet-130	53	14	following	follow	VERB
admet-130	53	15	the	the	DET
admet-130	53	16	single	single	ADJ
admet-130	53	17	topical	topical	ADJ
admet-130	53	18	application	application	NOUN
admet-130	53	19	for	for	ADP
admet-130	53	20	the	the	DET
admet-130	53	21	presence	presence	NOUN
admet-130	53	22	of	of	ADP
admet-130	53	23	the	the	DET
admet-130	53	24	formulated	formulate	VERB
admet-130	53	25	active	active	ADJ
admet-130	53	26	pharmacological	pharmacological	ADJ
admet-130	53	27	ingredient	ingredient	NOUN
admet-130	53	28	(	(	PUNCT
admet-130	53	29	bc	bc	PROPN
admet-130	53	30	-	-	PUNCT
admet-130	53	31	dn-01	dn-01	NOUN
admet-130	53	32	:	:	PUNCT
admet-130	53	33	benfotiamine	benfotiamine	ADJ
admet-130	53	34	)	)	PUNCT
admet-130	53	35	;	;	PUNCT
admet-130	53	36	the	the	DET
admet-130	53	37	dephosphorylated	dephosphorylate	VERB
admet-130	53	38	drug	drug	NOUN
admet-130	53	39	intermediate	intermediate	ADJ
admet-130	53	40	(	(	PUNCT
admet-130	53	41	sbt	sbt	NOUN
admet-130	53	42	:	:	PUNCT
admet-130	53	43	s	s	NOUN
admet-130	53	44	-	-	NOUN
admet-130	53	45	benzoylthiamine	benzoylthiamine	NOUN
admet-130	53	46	)	)	PUNCT
admet-130	53	47	;	;	PUNCT
admet-130	53	48	as	as	ADV
admet-130	53	49	well	well	ADV
admet-130	53	50	as	as	ADP
admet-130	53	51	the	the	DET
admet-130	53	52	cellular	cellular	ADJ
admet-130	53	53	metabolites	metabolite	NOUN
admet-130	53	54	of	of	ADP
admet-130	53	55	thiamine	thiamine	NOUN
admet-130	53	56	(	(	PUNCT
admet-130	53	57	t	t	PROPN
admet-130	53	58	)	)	PUNCT
admet-130	53	59	;	;	PUNCT
admet-130	53	60	thiamine	thiamine	NOUN
admet-130	53	61	diphosphate	diphosphate	PROPN
admet-130	53	62	;	;	PUNCT
admet-130	53	63	(	(	PUNCT
admet-130	53	64	tdp	tdp	NOUN
admet-130	53	65	)	)	PUNCT
admet-130	53	66	and	and	CCONJ
admet-130	53	67	thiamine	thiamine	NOUN
admet-130	53	68	monophosphate	monophosphate	NOUN
admet-130	53	69	(	(	PUNCT
admet-130	53	70	tmp	tmp	NOUN
admet-130	53	71	)	)	PUNCT
admet-130	53	72	.	.	PUNCT
admet-130	54	1	results	result	NOUN
admet-130	54	2	and	and	CCONJ
admet-130	54	3	discussion	discussion	VERB
admet-130	54	4	the	the	DET
admet-130	54	5	biochemistry	biochemistry	NOUN
admet-130	54	6	and	and	CCONJ
admet-130	54	7	required	require	VERB
admet-130	54	8	chemical	chemical	NOUN
admet-130	54	9	conversions	conversion	NOUN
admet-130	54	10	for	for	ADP
admet-130	54	11	benfotiamine	benfotiamine	ADJ
admet-130	54	12	from	from	ADP
admet-130	54	13	a	a	DET
admet-130	54	14	phosphorylated	phosphorylate	VERB
admet-130	54	15	openringed	openringed	ADJ
admet-130	54	16	structure	structure	NOUN
admet-130	54	17	to	to	ADP
admet-130	54	18	a	a	DET
admet-130	54	19	de	de	ADJ
admet-130	54	20	-	-	ADJ
admet-130	54	21	phosphorylated	phosphorylate	VERB
admet-130	54	22	closed	closed	ADJ
admet-130	54	23	ring	ring	NOUN
admet-130	54	24	and	and	CCONJ
admet-130	54	25	then	then	ADV
admet-130	54	26	subsequently	subsequently	ADV
admet-130	54	27	forming	form	VERB
admet-130	54	28	thiamine	thiamine	NOUN
admet-130	54	29	and	and	CCONJ
admet-130	54	30	the	the	DET
admet-130	54	31	phosphorylated	phosphorylate	VERB
admet-130	54	32	species	specie	NOUN
admet-130	54	33	of	of	ADP
admet-130	54	34	thiamine	thiamine	NOUN
admet-130	54	35	to	to	PART
admet-130	54	36	serve	serve	VERB
admet-130	54	37	as	as	ADP
admet-130	54	38	cofactors	cofactor	NOUN
admet-130	54	39	in	in	ADP
admet-130	54	40	the	the	DET
admet-130	54	41	transketolase	transketolase	NOUN
admet-130	54	42	reactions	reaction	NOUN
admet-130	54	43	are	be	AUX
admet-130	54	44	found	find	VERB
admet-130	54	45	in	in	ADP
admet-130	54	46	many	many	ADJ
admet-130	54	47	cell	cell	NOUN
admet-130	54	48	types	type	NOUN
admet-130	54	49	including	include	VERB
admet-130	54	50	the	the	DET
admet-130	54	51	skin	skin	NOUN
admet-130	54	52	tissue	tissue	NOUN
admet-130	54	53	epidermal	epidermal	ADJ
admet-130	54	54	and	and	CCONJ
admet-130	54	55	dermal	dermal	ADJ
admet-130	54	56	cells	cell	NOUN
admet-130	54	57	,	,	PUNCT
admet-130	54	58	as	as	ADV
admet-130	54	59	well	well	ADV
admet-130	54	60	as	as	ADP
admet-130	54	61	presumably	presumably	ADV
admet-130	54	62	peripheral	peripheral	ADJ
admet-130	54	63	nerve	nerve	NOUN
admet-130	54	64	endings	ending	NOUN
admet-130	54	65	in	in	ADP
admet-130	54	66	the	the	DET
admet-130	54	67	skin	skin	NOUN
admet-130	54	68	[	[	X
admet-130	54	69	22,23,59	22,23,59	NUM
admet-130	54	70	-	-	SYM
admet-130	54	71	62	62	NUM
admet-130	54	72	]	]	PUNCT
admet-130	54	73	.	.	PUNCT
admet-130	55	1	we	we	PRON
admet-130	55	2	believe	believe	VERB
admet-130	55	3	that	that	SCONJ
admet-130	55	4	the	the	DET
admet-130	55	5	delivery	delivery	NOUN
admet-130	55	6	of	of	ADP
admet-130	55	7	benfotiamine	benfotiamine	ADJ
admet-130	55	8	to	to	ADP
admet-130	55	9	a	a	DET
admet-130	55	10	patient	patient	NOUN
admet-130	55	11	via	via	ADP
admet-130	55	12	a	a	DET
admet-130	55	13	topical	topical	ADJ
admet-130	55	14	route	route	NOUN
admet-130	55	15	,	,	PUNCT
admet-130	55	16	as	as	SCONJ
admet-130	55	17	opposed	oppose	VERB
admet-130	55	18	to	to	ADP
admet-130	55	19	an	an	DET
admet-130	55	20	oral	oral	ADJ
admet-130	55	21	administration	administration	NOUN
admet-130	55	22	,	,	PUNCT
admet-130	55	23	offers	offer	VERB
admet-130	55	24	significantly	significantly	ADV
admet-130	55	25	greater	great	ADJ
admet-130	55	26	efficacy	efficacy	NOUN
admet-130	55	27	as	as	ADP
admet-130	55	28	a	a	DET
admet-130	55	29	result	result	NOUN
admet-130	55	30	of	of	ADP
admet-130	55	31	the	the	DET
admet-130	55	32	greater	great	ADJ
admet-130	55	33	quantity	quantity	NOUN
admet-130	55	34	of	of	ADP
admet-130	55	35	the	the	DET
admet-130	55	36	drug	drug	NOUN
admet-130	55	37	directly	directly	ADV
admet-130	55	38	deposited	deposit	VERB
admet-130	55	39	into	into	ADP
admet-130	55	40	the	the	DET
admet-130	55	41	skin	skin	NOUN
admet-130	55	42	tissue	tissue	NOUN
admet-130	55	43	where	where	SCONJ
admet-130	55	44	the	the	DET
admet-130	55	45	neuronal	neuronal	ADJ
admet-130	55	46	endings	ending	NOUN
admet-130	55	47	are	be	AUX
admet-130	55	48	located	locate	VERB
admet-130	55	49	.	.	PUNCT
admet-130	56	1	to	to	PART
admet-130	56	2	examine	examine	VERB
admet-130	56	3	this	this	DET
admet-130	56	4	concept	concept	NOUN
admet-130	56	5	,	,	PUNCT
admet-130	56	6	we	we	PRON
admet-130	56	7	initiated	initiate	VERB
admet-130	56	8	a	a	DET
admet-130	56	9	set	set	NOUN
admet-130	56	10	of	of	ADP
admet-130	56	11	experiments	experiment	NOUN
admet-130	56	12	to	to	PART
admet-130	56	13	first	first	ADV
admet-130	56	14	demonstrate	demonstrate	VERB
admet-130	56	15	the	the	DET
admet-130	56	16	viability	viability	NOUN
admet-130	56	17	and	and	CCONJ
admet-130	56	18	stability	stability	NOUN
admet-130	56	19	of	of	ADP
admet-130	56	20	preparing	prepare	VERB
admet-130	56	21	a	a	DET
admet-130	56	22	topical	topical	ADJ
admet-130	56	23	formulation	formulation	NOUN
admet-130	56	24	of	of	ADP
admet-130	56	25	benfotiamine	benfotiamine	ADJ
admet-130	56	26	.	.	PUNCT
admet-130	57	1	while	while	SCONJ
admet-130	57	2	the	the	DET
admet-130	57	3	substance	substance	NOUN
admet-130	57	4	benfotiamine	benfotiamine	NOUN
admet-130	57	5	has	have	AUX
admet-130	57	6	been	be	AUX
admet-130	57	7	available	available	ADJ
admet-130	57	8	for	for	ADP
admet-130	57	9	use	use	NOUN
admet-130	57	10	as	as	ADP
admet-130	57	11	a	a	DET
admet-130	57	12	solid	solid	ADJ
admet-130	57	13	and	and	CCONJ
admet-130	57	14	orally	orally	ADV
admet-130	57	15	delivered	deliver	VERB
admet-130	57	16	therapeutic	therapeutic	ADV
admet-130	57	17	for	for	ADP
admet-130	57	18	several	several	ADJ
admet-130	57	19	years	year	NOUN
admet-130	57	20	the	the	DET
admet-130	57	21	development	development	NOUN
admet-130	57	22	of	of	ADP
admet-130	57	23	a	a	DET
admet-130	57	24	novel	novel	ADJ
admet-130	57	25	topical	topical	ADJ
admet-130	57	26	formulation	formulation	NOUN
admet-130	57	27	of	of	ADP
admet-130	57	28	benfotiamine	benfotiamine	PROPN
admet-130	57	29	has	have	AUX
admet-130	57	30	been	be	AUX
admet-130	57	31	completed	complete	VERB
admet-130	57	32	for	for	ADP
admet-130	57	33	these	these	DET
admet-130	57	34	studies	study	NOUN
admet-130	57	35	.	.	PUNCT
admet-130	58	1	we	we	PRON
admet-130	58	2	formulated	formulate	VERB
admet-130	58	3	benfotiamine	benfotiamine	ADJ
admet-130	58	4	into	into	ADP
admet-130	58	5	topical	topical	ADJ
admet-130	58	6	preparation	preparation	NOUN
admet-130	58	7	to	to	PART
admet-130	58	8	maximize	maximize	VERB
admet-130	58	9	local	local	ADJ
admet-130	58	10	drug	drug	NOUN
admet-130	58	11	accumulation	accumulation	NOUN
admet-130	58	12	and	and	CCONJ
admet-130	58	13	to	to	PART
admet-130	58	14	minimize	minimize	VERB
admet-130	58	15	systemic	systemic	ADJ
admet-130	58	16	distribution	distribution	NOUN
admet-130	58	17	[	[	X
admet-130	58	18	65	65	NUM
admet-130	58	19	]	]	PUNCT
admet-130	58	20	.	.	PUNCT
admet-130	59	1	the	the	DET
admet-130	59	2	goal	goal	NOUN
admet-130	59	3	of	of	ADP
admet-130	59	4	these	these	DET
admet-130	59	5	formulations	formulation	NOUN
admet-130	59	6	and	and	CCONJ
admet-130	59	7	administration	administration	NOUN
admet-130	59	8	route	route	NOUN
admet-130	59	9	was	be	AUX
admet-130	59	10	to	to	PART
admet-130	59	11	deliver	deliver	VERB
admet-130	59	12	significantly	significantly	ADV
admet-130	59	13	greater	great	ADJ
admet-130	59	14	quantities	quantity	NOUN
admet-130	59	15	of	of	ADP
admet-130	59	16	the	the	DET
admet-130	59	17	drug	drug	NOUN
admet-130	59	18	to	to	ADP
admet-130	59	19	the	the	DET
admet-130	59	20	afflicted	afflict	VERB
admet-130	59	21	peripheral	peripheral	ADJ
admet-130	59	22	dermal	dermal	ADJ
admet-130	59	23	neuronal	neuronal	ADJ
admet-130	59	24	tissue	tissue	NOUN
admet-130	59	25	.	.	PUNCT
admet-130	60	1	next	next	ADV
admet-130	60	2	,	,	PUNCT
admet-130	60	3	we	we	PRON
admet-130	60	4	have	have	AUX
admet-130	60	5	performed	perform	VERB
admet-130	60	6	a	a	DET
admet-130	60	7	series	series	NOUN
admet-130	60	8	of	of	ADP
admet-130	60	9	animal	animal	NOUN
admet-130	60	10	pharmacokinetic	pharmacokinetic	ADJ
admet-130	60	11	and	and	CCONJ
admet-130	60	12	tissue	tissue	NOUN
admet-130	60	13	deposition	deposition	NOUN
admet-130	60	14	experiments	experiment	NOUN
admet-130	60	15	to	to	PART
admet-130	60	16	determine	determine	VERB
admet-130	60	17	the	the	DET
admet-130	60	18	time	time	NOUN
admet-130	60	19	course	course	NOUN
admet-130	60	20	of	of	ADP
admet-130	60	21	appearance	appearance	NOUN
admet-130	60	22	of	of	ADP
admet-130	60	23	thiamine	thiamine	NOUN
admet-130	60	24	derivatives	derivative	NOUN
admet-130	60	25	in	in	ADP
admet-130	60	26	the	the	DET
admet-130	60	27	plasma	plasma	NOUN
admet-130	60	28	after	after	ADP
admet-130	60	29	treatment	treatment	NOUN
admet-130	60	30	with	with	ADP
admet-130	60	31	benfotiamine	benfotiamine	ADJ
admet-130	60	32	formulations	formulation	NOUN
admet-130	60	33	.	.	PUNCT
admet-130	61	1	in	in	ADP
admet-130	61	2	addition	addition	NOUN
admet-130	61	3	,	,	PUNCT
admet-130	61	4	we	we	PRON
admet-130	61	5	also	also	ADV
admet-130	61	6	analyzed	analyze	VERB
admet-130	61	7	the	the	DET
admet-130	61	8	amounts	amount	NOUN
admet-130	61	9	of	of	ADP
admet-130	61	10	thiamine	thiamine	NOUN
admet-130	61	11	and	and	CCONJ
admet-130	61	12	the	the	DET
admet-130	61	13	phosphorylated	phosphorylate	VERB
admet-130	61	14	cellular	cellular	ADJ
admet-130	61	15	metabolites	metabolite	NOUN
admet-130	61	16	in	in	ADP
admet-130	61	17	the	the	DET
admet-130	61	18	skin	skin	NOUN
admet-130	61	19	tissue	tissue	NOUN
admet-130	61	20	at	at	ADP
admet-130	61	21	a	a	DET
admet-130	61	22	24	24	NUM
admet-130	61	23	h	h	NOUN
admet-130	61	24	time	time	NOUN
admet-130	61	25	point	point	NOUN
admet-130	61	26	after	after	ADP
admet-130	61	27	topical	topical	ADJ
admet-130	61	28	treatment	treatment	NOUN
admet-130	61	29	with	with	ADP
admet-130	61	30	benfotiamine	benfotiamine	ADJ
admet-130	61	31	.	.	PUNCT
admet-130	62	1	we	we	PRON
admet-130	62	2	measured	measure	VERB
admet-130	62	3	the	the	DET
admet-130	62	4	thiamine	thiamine	NOUN
admet-130	62	5	(	(	PUNCT
admet-130	62	6	t	t	NOUN
admet-130	62	7	)	)	PUNCT
admet-130	62	8	,	,	PUNCT
admet-130	62	9	thiamine	thiamine	NOUN
admet-130	62	10	diphosphate	diphosphate	PROPN
admet-130	62	11	(	(	PUNCT
admet-130	62	12	tdp	tdp	NOUN
admet-130	62	13	)	)	PUNCT
admet-130	62	14	,	,	PUNCT
admet-130	62	15	thiamine	thiamine	NOUN
admet-130	62	16	monophosphate	monophosphate	NOUN
admet-130	62	17	(	(	PUNCT
admet-130	62	18	tmp	tmp	NOUN
admet-130	62	19	)	)	PUNCT
admet-130	62	20	and	and	CCONJ
admet-130	62	21	calculated	calculate	VERB
admet-130	62	22	the	the	DET
admet-130	62	23	level	level	NOUN
admet-130	62	24	of	of	ADP
admet-130	62	25	total	total	ADJ
admet-130	62	26	thiamine	thiamine	NOUN
admet-130	62	27	derivatives	derivative	NOUN
admet-130	62	28	(	(	PUNCT
admet-130	62	29	total	total	NOUN
admet-130	62	30	)	)	PUNCT
admet-130	62	31	in	in	ADP
admet-130	62	32	the	the	DET
admet-130	62	33	blood	blood	NOUN
admet-130	62	34	after	after	SCONJ
admet-130	62	35	the	the	DET
admet-130	62	36	application	application	NOUN
admet-130	62	37	of	of	ADP
admet-130	62	38	0.5	0.5	NUM
admet-130	62	39	g	g	NOUN
admet-130	62	40	of	of	ADP
admet-130	62	41	3	3	NUM
admet-130	62	42	%	%	NOUN
admet-130	62	43	solubilized	solubilize	VERB
admet-130	62	44	benfotiamine	benfotiamine	ADJ
admet-130	62	45	topical	topical	ADJ
admet-130	62	46	formulation	formulation	NOUN
admet-130	62	47	.	.	PUNCT
admet-130	63	1	upon	upon	SCONJ
admet-130	63	2	treatment	treatment	NOUN
admet-130	63	3	,	,	PUNCT
admet-130	63	4	we	we	PRON
admet-130	63	5	observed	observe	VERB
admet-130	63	6	a	a	DET
admet-130	63	7	sharp	sharp	ADJ
admet-130	63	8	rise	rise	NOUN
admet-130	63	9	in	in	ADP
admet-130	63	10	the	the	DET
admet-130	63	11	blood	blood	NOUN
admet-130	63	12	concentration	concentration	NOUN
admet-130	63	13	of	of	ADP
admet-130	63	14	each	each	PRON
admet-130	63	15	of	of	ADP
admet-130	63	16	the	the	DET
admet-130	63	17	thiamine	thiamine	NOUN
admet-130	63	18	derivatives	derivative	NOUN
admet-130	63	19	within	within	ADP
admet-130	63	20	30	30	NUM
admet-130	63	21	minutes	minute	NOUN
admet-130	63	22	of	of	ADP
admet-130	63	23	the	the	DET
admet-130	63	24	drug	drug	NOUN
admet-130	63	25	application	application	NOUN
admet-130	63	26	(	(	PUNCT
admet-130	63	27	figure	figure	NOUN
admet-130	63	28	1	1	NUM
admet-130	63	29	)	)	PUNCT
admet-130	63	30	.	.	PUNCT
admet-130	64	1	there	there	PRON
admet-130	64	2	was	be	VERB
admet-130	64	3	an	an	DET
admet-130	64	4	additional	additional	ADJ
admet-130	64	5	increase	increase	NOUN
admet-130	64	6	until	until	ADP
admet-130	64	7	one	one	NUM
admet-130	64	8	hour	hour	NOUN
admet-130	64	9	,	,	PUNCT
admet-130	64	10	followed	follow	VERB
admet-130	64	11	by	by	ADP
admet-130	64	12	a	a	DET
admet-130	64	13	modest	modest	ADJ
admet-130	64	14	decline	decline	NOUN
admet-130	64	15	until	until	ADP
admet-130	64	16	two	two	NUM
admet-130	64	17	hours	hour	NOUN
admet-130	64	18	,	,	PUNCT
admet-130	64	19	then	then	ADV
admet-130	64	20	the	the	DET
admet-130	64	21	admet	admet	PROPN
admet-130	64	22	&	&	CCONJ
admet-130	64	23	dmpk	dmpk	PROPN
admet-130	64	24	2(4	2(4	NUM
admet-130	64	25	)	)	PUNCT
admet-130	64	26	(	(	PUNCT
admet-130	64	27	2014	2014	NUM
admet-130	64	28	)	)	PUNCT
admet-130	64	29	272	272	NUM
admet-130	64	30	-	-	SYM
admet-130	64	31	281	281	NUM
admet-130	64	32	transderamal	transderamal	ADJ
admet-130	64	33	delivery	delivery	NOUN
admet-130	64	34	of	of	ADP
admet-130	64	35	benfotiamine	benfotiamine	ADJ
admet-130	64	36	in	in	ADP
admet-130	64	37	an	an	DET
admet-130	64	38	animal	animal	NOUN
admet-130	64	39	model	model	NOUN
admet-130	64	40	doi	doi	NOUN
admet-130	64	41	:	:	PUNCT
admet-130	64	42	10.5599	10.5599	NUM
admet-130	64	43	/	/	SYM
admet-130	64	44	admet.2.4.130	admet.2.4.130	PROPN
admet-130	64	45	275	275	NUM
admet-130	64	46	blood	blood	NOUN
admet-130	64	47	concentration	concentration	NOUN
admet-130	64	48	of	of	ADP
admet-130	64	49	the	the	DET
admet-130	64	50	individual	individual	ADJ
admet-130	64	51	derivatives	derivative	NOUN
admet-130	64	52	and	and	CCONJ
admet-130	64	53	the	the	DET
admet-130	64	54	total	total	NOUN
admet-130	64	55	remained	remain	VERB
admet-130	64	56	at	at	ADP
admet-130	64	57	an	an	DET
admet-130	64	58	elevated	elevated	ADJ
admet-130	64	59	level	level	NOUN
admet-130	64	60	until	until	ADP
admet-130	64	61	24	24	NUM
admet-130	64	62	h	h	NOUN
admet-130	64	63	after	after	ADP
admet-130	64	64	the	the	DET
admet-130	64	65	application	application	NOUN
admet-130	64	66	(	(	PUNCT
admet-130	64	67	figure	figure	NOUN
admet-130	64	68	1	1	NUM
admet-130	64	69	)	)	PUNCT
admet-130	64	70	.	.	PUNCT
admet-130	65	1	figure	figure	NOUN
admet-130	65	2	1	1	NUM
admet-130	65	3	.	.	PUNCT
admet-130	66	1	plasma	plasma	NOUN
admet-130	66	2	concentration	concentration	NOUN
admet-130	66	3	of	of	ADP
admet-130	66	4	cellular	cellular	ADJ
admet-130	66	5	metabolites	metabolite	NOUN
admet-130	66	6	after	after	ADP
admet-130	66	7	topical	topical	ADJ
admet-130	66	8	application	application	NOUN
admet-130	66	9	of	of	ADP
admet-130	66	10	15	15	NUM
admet-130	66	11	mg	mg	PROPN
admet-130	66	12	bc	bc	PROPN
admet-130	66	13	-	-	PUNCT
admet-130	66	14	dn-01	dn-01	ADV
admet-130	66	15	(	(	PUNCT
admet-130	66	16	solubilized	solubilize	VERB
admet-130	66	17	)	)	PUNCT
admet-130	66	18	.	.	PUNCT
admet-130	67	1	the	the	DET
admet-130	67	2	pharmacokinetic	pharmacokinetic	ADJ
admet-130	67	3	profile	profile	NOUN
admet-130	67	4	of	of	ADP
admet-130	67	5	plasma	plasma	NOUN
admet-130	67	6	concentrations	concentration	NOUN
admet-130	67	7	of	of	ADP
admet-130	67	8	thiamine	thiamine	NOUN
admet-130	67	9	(	(	PUNCT
admet-130	67	10	t	t	NOUN
admet-130	67	11	)	)	PUNCT
admet-130	67	12	,	,	PUNCT
admet-130	67	13	thiamine	thiamine	NOUN
admet-130	67	14	diphosphate	diphosphate	PROPN
admet-130	67	15	(	(	PUNCT
admet-130	67	16	tdp	tdp	NOUN
admet-130	67	17	)	)	PUNCT
admet-130	67	18	and	and	CCONJ
admet-130	67	19	thiamine	thiamine	NOUN
admet-130	67	20	monophosphate	monophosphate	NOUN
admet-130	67	21	(	(	PUNCT
admet-130	67	22	tmp	tmp	NOUN
admet-130	67	23	)	)	PUNCT
admet-130	67	24	were	be	AUX
admet-130	67	25	analyzed	analyze	VERB
admet-130	67	26	following	follow	VERB
admet-130	67	27	the	the	DET
admet-130	67	28	single	single	ADJ
admet-130	67	29	application	application	NOUN
admet-130	67	30	15	15	NUM
admet-130	67	31	mg	mg	NOUN
admet-130	67	32	of	of	ADP
admet-130	67	33	topical	topical	ADJ
admet-130	67	34	bc	bc	PROPN
admet-130	67	35	-	-	PUNCT
admet-130	67	36	dn-01	dn-01	NOUN
admet-130	67	37	.	.	PUNCT
admet-130	68	1	the	the	DET
admet-130	68	2	data	datum	NOUN
admet-130	68	3	shows	show	VERB
admet-130	68	4	a	a	DET
admet-130	68	5	rapid	rapid	ADJ
admet-130	68	6	penetration	penetration	NOUN
admet-130	68	7	through	through	ADP
admet-130	68	8	the	the	DET
admet-130	68	9	skin	skin	NOUN
admet-130	68	10	into	into	ADP
admet-130	68	11	the	the	DET
admet-130	68	12	plasma	plasma	NOUN
admet-130	68	13	for	for	ADP
admet-130	68	14	all	all	DET
admet-130	68	15	three	three	NUM
admet-130	68	16	thiamine	thiamine	NOUN
admet-130	68	17	derivatives	derivative	NOUN
admet-130	68	18	with	with	ADP
admet-130	68	19	a	a	DET
admet-130	68	20	peak	peak	NOUN
admet-130	68	21	for	for	ADP
admet-130	68	22	the	the	DET
admet-130	68	23	cumulative	cumulative	ADJ
admet-130	68	24	group	group	NOUN
admet-130	68	25	at	at	ADP
admet-130	68	26	1	1	NUM
admet-130	68	27	hour	hour	NOUN
admet-130	68	28	,	,	PUNCT
admet-130	68	29	however	however	ADV
admet-130	68	30	,	,	PUNCT
admet-130	68	31	holding	hold	VERB
admet-130	68	32	an	an	DET
admet-130	68	33	approximate	approximate	ADJ
admet-130	68	34	50	50	NUM
admet-130	68	35	%	%	NOUN
admet-130	68	36	increase	increase	NOUN
admet-130	68	37	over	over	ADP
admet-130	68	38	normal	normal	ADJ
admet-130	68	39	level	level	NOUN
admet-130	68	40	up	up	ADP
admet-130	68	41	to	to	PART
admet-130	68	42	24	24	NUM
admet-130	68	43	hours	hour	NOUN
admet-130	68	44	.	.	PUNCT
admet-130	69	1	n=5	n=5	PRON
admet-130	69	2	for	for	ADP
admet-130	69	3	plasma	plasma	NOUN
admet-130	69	4	data	datum	NOUN
admet-130	69	5	.	.	PUNCT
admet-130	70	1	the	the	DET
admet-130	70	2	application	application	NOUN
admet-130	70	3	of	of	ADP
admet-130	70	4	0.5	0.5	NUM
admet-130	70	5	g	g	NOUN
admet-130	70	6	of	of	ADP
admet-130	70	7	5	5	NUM
admet-130	70	8	%	%	NOUN
admet-130	70	9	microcrystalline	microcrystalline	NOUN
admet-130	70	10	benfotiamine	benfotiamine	ADJ
admet-130	70	11	topical	topical	ADJ
admet-130	70	12	formulation	formulation	NOUN
admet-130	70	13	resulted	result	VERB
admet-130	70	14	in	in	ADP
admet-130	70	15	an	an	DET
admet-130	70	16	appreciable	appreciable	ADJ
admet-130	70	17	enhancement	enhancement	NOUN
admet-130	70	18	of	of	ADP
admet-130	70	19	thiamine	thiamine	NOUN
admet-130	70	20	and	and	CCONJ
admet-130	70	21	its	its	PRON
admet-130	70	22	phosphorylated	phosphorylate	VERB
admet-130	70	23	derivatives	derivative	NOUN
admet-130	70	24	in	in	ADP
admet-130	70	25	the	the	DET
admet-130	70	26	blood	blood	NOUN
admet-130	70	27	.	.	PUNCT
admet-130	71	1	again	again	ADV
admet-130	71	2	,	,	PUNCT
admet-130	71	3	a	a	DET
admet-130	71	4	sharp	sharp	ADJ
admet-130	71	5	rise	rise	NOUN
admet-130	71	6	was	be	AUX
admet-130	71	7	observed	observe	VERB
admet-130	71	8	in	in	ADP
admet-130	71	9	the	the	DET
admet-130	71	10	blood	blood	NOUN
admet-130	71	11	concentration	concentration	NOUN
admet-130	71	12	of	of	ADP
admet-130	71	13	each	each	PRON
admet-130	71	14	of	of	ADP
admet-130	71	15	the	the	DET
admet-130	71	16	thiamine	thiamine	NOUN
admet-130	71	17	derivatives	derivative	NOUN
admet-130	71	18	within	within	ADP
admet-130	71	19	30	30	NUM
admet-130	71	20	minutes	minute	NOUN
admet-130	71	21	of	of	ADP
admet-130	71	22	the	the	DET
admet-130	71	23	drug	drug	NOUN
admet-130	71	24	application	application	NOUN
admet-130	71	25	(	(	PUNCT
admet-130	71	26	figure	figure	NOUN
admet-130	71	27	2	2	NUM
admet-130	71	28	)	)	PUNCT
admet-130	71	29	.	.	PUNCT
admet-130	72	1	this	this	DET
admet-130	72	2	enhancement	enhancement	NOUN
admet-130	72	3	continued	continue	VERB
admet-130	72	4	to	to	PART
admet-130	72	5	further	far	ADV
admet-130	72	6	increase	increase	VERB
admet-130	72	7	until	until	ADP
admet-130	72	8	one	one	NUM
admet-130	72	9	hour	hour	NOUN
admet-130	72	10	,	,	PUNCT
admet-130	72	11	followed	follow	VERB
admet-130	72	12	by	by	ADP
admet-130	72	13	a	a	DET
admet-130	72	14	sharp	sharp	ADJ
admet-130	72	15	decline	decline	NOUN
admet-130	72	16	in	in	ADP
admet-130	72	17	the	the	DET
admet-130	72	18	blood	blood	NOUN
admet-130	72	19	concentration	concentration	NOUN
admet-130	72	20	of	of	ADP
admet-130	72	21	the	the	DET
admet-130	72	22	individual	individual	ADJ
admet-130	72	23	derivatives	derivative	NOUN
admet-130	72	24	and	and	CCONJ
admet-130	72	25	the	the	DET
admet-130	72	26	total	total	NOUN
admet-130	72	27	remained	remain	VERB
admet-130	72	28	at	at	ADP
admet-130	72	29	an	an	DET
admet-130	72	30	elevated	elevated	ADJ
admet-130	72	31	level	level	NOUN
admet-130	72	32	until	until	ADP
admet-130	72	33	24	24	NUM
admet-130	72	34	hrs	hrs	NOUN
admet-130	72	35	after	after	ADP
admet-130	72	36	the	the	DET
admet-130	72	37	application	application	NOUN
admet-130	72	38	.	.	PUNCT
admet-130	73	1	interestingly	interestingly	ADV
admet-130	73	2	,	,	PUNCT
admet-130	73	3	while	while	SCONJ
admet-130	73	4	the	the	DET
admet-130	73	5	microcrystalline	microcrystalline	NOUN
admet-130	73	6	formulation	formulation	NOUN
admet-130	73	7	contained	contain	VERB
admet-130	73	8	almost	almost	ADV
admet-130	73	9	twice	twice	ADV
admet-130	73	10	as	as	ADV
admet-130	73	11	high	high	ADJ
admet-130	73	12	concentration	concentration	NOUN
admet-130	73	13	of	of	ADP
admet-130	73	14	the	the	DET
admet-130	73	15	active	active	ADJ
admet-130	73	16	pharmacological	pharmacological	NOUN
admet-130	73	17	ingredient	ingredient	NOUN
admet-130	73	18	than	than	ADP
admet-130	73	19	the	the	DET
admet-130	73	20	solubilized	solubilize	VERB
admet-130	73	21	benfotiamine	benfotiamine	ADJ
admet-130	73	22	formulation	formulation	NOUN
admet-130	73	23	,	,	PUNCT
admet-130	73	24	the	the	DET
admet-130	73	25	24	24	NUM
admet-130	73	26	hours	hour	NOUN
admet-130	73	27	steady	steady	ADJ
admet-130	73	28	state	state	NOUN
admet-130	73	29	concentrations	concentration	NOUN
admet-130	73	30	in	in	ADP
admet-130	73	31	the	the	DET
admet-130	73	32	blood	blood	NOUN
admet-130	73	33	resembled	resemble	VERB
admet-130	73	34	to	to	ADP
admet-130	73	35	those	those	DET
admet-130	73	36	values	value	NOUN
admet-130	73	37	that	that	PRON
admet-130	73	38	were	be	AUX
admet-130	73	39	observed	observe	VERB
admet-130	73	40	with	with	ADP
admet-130	73	41	the	the	DET
admet-130	73	42	solubilized	solubilize	VERB
admet-130	73	43	formulation	formulation	NOUN
admet-130	73	44	containing	contain	VERB
admet-130	73	45	a	a	DET
admet-130	73	46	lower	low	ADJ
admet-130	73	47	(	(	PUNCT
admet-130	73	48	3	3	NUM
admet-130	73	49	%	%	NOUN
admet-130	73	50	)	)	PUNCT
admet-130	73	51	benfotiamine	benfotiamine	ADJ
admet-130	73	52	concentration	concentration	NOUN
admet-130	73	53	.	.	PUNCT
admet-130	74	1	this	this	PRON
admet-130	74	2	is	be	AUX
admet-130	74	3	an	an	DET
admet-130	74	4	indication	indication	NOUN
admet-130	74	5	that	that	SCONJ
admet-130	74	6	in	in	ADP
admet-130	74	7	case	case	NOUN
admet-130	74	8	of	of	ADP
admet-130	74	9	each	each	DET
admet-130	74	10	applied	apply	VERB
admet-130	74	11	formulation	formulation	NOUN
admet-130	74	12	the	the	DET
admet-130	74	13	benfotiamine	benfotiamine	ADJ
admet-130	74	14	level	level	NOUN
admet-130	74	15	was	be	AUX
admet-130	74	16	at	at	ADP
admet-130	74	17	saturating	saturate	VERB
admet-130	74	18	concentration	concentration	NOUN
admet-130	74	19	.	.	PUNCT
admet-130	75	1	moreover	moreover	ADV
admet-130	75	2	,	,	PUNCT
admet-130	75	3	the	the	DET
admet-130	75	4	more	more	ADV
admet-130	75	5	pronounced	pronounced	ADJ
admet-130	75	6	rise	rise	NOUN
admet-130	75	7	at	at	ADP
admet-130	75	8	one	one	NUM
admet-130	75	9	hour	hour	NOUN
admet-130	75	10	and	and	CCONJ
admet-130	75	11	the	the	DET
admet-130	75	12	drastic	drastic	ADJ
admet-130	75	13	drop	drop	NOUN
admet-130	75	14	thereafter	thereafter	ADV
admet-130	75	15	in	in	ADP
admet-130	75	16	the	the	DET
admet-130	75	17	concentration	concentration	NOUN
admet-130	75	18	of	of	ADP
admet-130	75	19	thiamine	thiamine	NOUN
admet-130	75	20	derivatives	derivative	NOUN
admet-130	75	21	is	be	AUX
admet-130	75	22	consistent	consistent	ADJ
admet-130	75	23	with	with	ADP
admet-130	75	24	a	a	DET
admet-130	75	25	robust	robust	ADJ
admet-130	75	26	overload	overload	NOUN
admet-130	75	27	(	(	PUNCT
admet-130	75	28	figure	figure	NOUN
admet-130	75	29	2	2	NUM
admet-130	75	30	)	)	PUNCT
admet-130	75	31	.	.	PUNCT
admet-130	76	1	varadi	varadi	PROPN
admet-130	76	2	et.al	et.al	PROPN
admet-130	76	3	.	.	PUNCT
admet-130	77	1	admet	admet	PROPN
admet-130	77	2	&	&	CCONJ
admet-130	77	3	dmpk	dmpk	PROPN
admet-130	77	4	2(4	2(4	NUM
admet-130	77	5	)	)	PUNCT
admet-130	77	6	(	(	PUNCT
admet-130	77	7	2014	2014	NUM
admet-130	77	8	)	)	PUNCT
admet-130	77	9	272	272	NUM
admet-130	77	10	-	-	SYM
admet-130	77	11	281	281	NUM
admet-130	77	12	276	276	NUM
admet-130	77	13	figure	figure	NOUN
admet-130	77	14	2	2	NUM
admet-130	77	15	.	.	PUNCT
admet-130	77	16	plasma	plasma	NOUN
admet-130	77	17	concentration	concentration	NOUN
admet-130	77	18	of	of	ADP
admet-130	77	19	cellular	cellular	ADJ
admet-130	77	20	metabolites	metabolite	NOUN
admet-130	77	21	after	after	ADP
admet-130	77	22	topical	topical	ADJ
admet-130	77	23	application	application	NOUN
admet-130	77	24	of	of	ADP
admet-130	77	25	25	25	NUM
admet-130	77	26	mg	mg	PROPN
admet-130	77	27	bc	bc	PROPN
admet-130	77	28	-	-	PUNCT
admet-130	77	29	dn-01	dn-01	NOUN
admet-130	77	30	(	(	PUNCT
admet-130	77	31	suspension	suspension	NOUN
admet-130	77	32	)	)	PUNCT
admet-130	77	33	.	.	PUNCT
admet-130	78	1	the	the	DET
admet-130	78	2	pharmacokinetic	pharmacokinetic	ADJ
admet-130	78	3	profile	profile	NOUN
admet-130	78	4	of	of	ADP
admet-130	78	5	plasma	plasma	NOUN
admet-130	78	6	concentrations	concentration	NOUN
admet-130	78	7	of	of	ADP
admet-130	78	8	thiamine	thiamine	NOUN
admet-130	78	9	(	(	PUNCT
admet-130	78	10	t	t	NOUN
admet-130	78	11	)	)	PUNCT
admet-130	78	12	,	,	PUNCT
admet-130	78	13	thiamine	thiamine	NOUN
admet-130	78	14	diphosphate	diphosphate	PROPN
admet-130	78	15	(	(	PUNCT
admet-130	78	16	tdp	tdp	NOUN
admet-130	78	17	)	)	PUNCT
admet-130	78	18	and	and	CCONJ
admet-130	78	19	thiamine	thiamine	NOUN
admet-130	78	20	monophosphate	monophosphate	NOUN
admet-130	78	21	(	(	PUNCT
admet-130	78	22	tmp	tmp	NOUN
admet-130	78	23	)	)	PUNCT
admet-130	78	24	were	be	AUX
admet-130	78	25	analyzed	analyze	VERB
admet-130	78	26	following	follow	VERB
admet-130	78	27	the	the	DET
admet-130	78	28	single	single	ADJ
admet-130	78	29	application	application	NOUN
admet-130	78	30	25	25	NUM
admet-130	78	31	mg	mg	NOUN
admet-130	78	32	of	of	ADP
admet-130	78	33	topical	topical	NOUN
admet-130	78	34	suspended	suspend	VERB
admet-130	78	35	bc	bc	PROPN
admet-130	78	36	-	-	PUNCT
admet-130	78	37	dn-01	dn-01	NOUN
admet-130	78	38	.	.	PUNCT
admet-130	79	1	the	the	DET
admet-130	79	2	data	datum	NOUN
admet-130	79	3	shows	show	VERB
admet-130	79	4	a	a	DET
admet-130	79	5	rapid	rapid	ADJ
admet-130	79	6	penetration	penetration	NOUN
admet-130	79	7	through	through	ADP
admet-130	79	8	the	the	DET
admet-130	79	9	skin	skin	NOUN
admet-130	79	10	into	into	ADP
admet-130	79	11	the	the	DET
admet-130	79	12	plasma	plasma	NOUN
admet-130	79	13	for	for	ADP
admet-130	79	14	all	all	DET
admet-130	79	15	three	three	NUM
admet-130	79	16	thiamine	thiamine	NOUN
admet-130	79	17	derivatives	derivative	NOUN
admet-130	79	18	with	with	ADP
admet-130	79	19	a	a	DET
admet-130	79	20	peak	peak	NOUN
admet-130	79	21	for	for	ADP
admet-130	79	22	the	the	DET
admet-130	79	23	cumulative	cumulative	ADJ
admet-130	79	24	group	group	NOUN
admet-130	79	25	at	at	ADP
admet-130	79	26	1	1	NUM
admet-130	79	27	hour	hour	NOUN
admet-130	79	28	with	with	ADP
admet-130	79	29	an	an	DET
admet-130	79	30	approximate	approximate	ADJ
admet-130	79	31	70	70	NUM
admet-130	79	32	%	%	NOUN
admet-130	79	33	increase	increase	NOUN
admet-130	79	34	in	in	ADP
admet-130	79	35	the	the	DET
admet-130	79	36	group	group	NOUN
admet-130	79	37	,	,	PUNCT
admet-130	79	38	however	however	ADV
admet-130	79	39	,	,	PUNCT
admet-130	79	40	dropping	drop	VERB
admet-130	79	41	off	off	ADP
admet-130	79	42	to	to	ADP
admet-130	79	43	a	a	DET
admet-130	79	44	more	more	ADV
admet-130	79	45	normal	normal	ADJ
admet-130	79	46	level	level	NOUN
admet-130	79	47	by	by	ADP
admet-130	79	48	4	4	NUM
admet-130	79	49	hours	hour	NOUN
admet-130	79	50	.	.	PUNCT
admet-130	80	1	n=5	n=5	PRON
admet-130	80	2	for	for	ADP
admet-130	80	3	plasma	plasma	NOUN
admet-130	80	4	data	datum	NOUN
admet-130	80	5	at	at	ADP
admet-130	80	6	0.5	0.5	NUM
admet-130	80	7	,	,	PUNCT
admet-130	80	8	1	1	NUM
admet-130	80	9	,	,	PUNCT
admet-130	80	10	2	2	NUM
admet-130	80	11	,	,	PUNCT
admet-130	80	12	4	4	NUM
admet-130	80	13	and	and	CCONJ
admet-130	80	14	8	8	NUM
admet-130	80	15	hours	hour	NOUN
admet-130	80	16	and	and	CCONJ
admet-130	80	17	n=1	n=1	PROPN
admet-130	80	18	at	at	ADP
admet-130	80	19	t=24	t=24	PROPN
admet-130	80	20	hours	hour	NOUN
admet-130	80	21	time	time	NOUN
admet-130	80	22	point	point	NOUN
admet-130	80	23	.	.	PUNCT
admet-130	81	1	the	the	DET
admet-130	81	2	measurement	measurement	NOUN
admet-130	81	3	of	of	ADP
admet-130	81	4	benfotiamine	benfotiamine	ADJ
admet-130	81	5	,	,	PUNCT
admet-130	81	6	s	s	NOUN
admet-130	81	7	-	-	PUNCT
admet-130	81	8	benzoyl	benzoyl	NOUN
admet-130	81	9	-	-	PUNCT
admet-130	81	10	benfotiamine	benfotiamine	ADJ
admet-130	81	11	,	,	PUNCT
admet-130	81	12	thiamine	thiamine	NOUN
admet-130	81	13	and	and	CCONJ
admet-130	81	14	thiamine	thiamine	NOUN
admet-130	81	15	related	relate	VERB
admet-130	81	16	compounds	compound	NOUN
admet-130	81	17	in	in	ADP
admet-130	81	18	skin	skin	NOUN
admet-130	81	19	tissues	tissue	NOUN
admet-130	81	20	attested	attest	VERB
admet-130	81	21	that	that	SCONJ
admet-130	81	22	there	there	PRON
admet-130	81	23	was	be	VERB
admet-130	81	24	no	no	DET
admet-130	81	25	obvious	obvious	ADJ
admet-130	81	26	change	change	NOUN
admet-130	81	27	of	of	ADP
admet-130	81	28	tdp	tdp	NOUN
admet-130	81	29	and	and	CCONJ
admet-130	81	30	tmp	tmp	NOUN
admet-130	81	31	levels	level	NOUN
admet-130	81	32	compared	compare	VERB
admet-130	81	33	to	to	ADP
admet-130	81	34	controls	control	NOUN
admet-130	81	35	over	over	ADP
admet-130	81	36	the	the	DET
admet-130	81	37	24	24	NUM
admet-130	81	38	hour	hour	NOUN
admet-130	81	39	period	period	NOUN
admet-130	81	40	when	when	SCONJ
admet-130	81	41	treated	treat	VERB
admet-130	81	42	with	with	ADP
admet-130	81	43	solubilized	solubilize	VERB
admet-130	81	44	benfotiamine	benfotiamine	ADJ
admet-130	81	45	cream	cream	NOUN
admet-130	81	46	(	(	PUNCT
admet-130	81	47	figure	figure	NOUN
admet-130	81	48	3a	3a	NUM
admet-130	81	49	)	)	PUNCT
admet-130	81	50	.	.	PUNCT
admet-130	82	1	the	the	DET
admet-130	82	2	level	level	NOUN
admet-130	82	3	of	of	ADP
admet-130	82	4	benfotiamine	benfotiamine	PROPN
admet-130	82	5	appeared	appear	VERB
admet-130	82	6	low	low	ADJ
admet-130	82	7	,	,	PUNCT
admet-130	82	8	however	however	ADV
admet-130	82	9	,	,	PUNCT
admet-130	82	10	there	there	PRON
admet-130	82	11	was	be	VERB
admet-130	82	12	a	a	DET
admet-130	82	13	drastic	drastic	ADJ
admet-130	82	14	rise	rise	NOUN
admet-130	82	15	in	in	ADP
admet-130	82	16	s	s	ADJ
admet-130	82	17	-	-	PUNCT
admet-130	82	18	benzoyl	benzoyl	ADJ
admet-130	82	19	thiamine	thiamine	NOUN
admet-130	82	20	and	and	CCONJ
admet-130	82	21	thiamine	thiamine	NOUN
admet-130	82	22	levels	level	NOUN
admet-130	82	23	.	.	PUNCT
admet-130	83	1	as	as	SCONJ
admet-130	83	2	shown	show	VERB
admet-130	83	3	in	in	ADP
admet-130	83	4	figure	figure	NOUN
admet-130	83	5	3a	3a	NUM
admet-130	83	6	,	,	PUNCT
admet-130	83	7	bft	bft	NOUN
admet-130	83	8	and	and	CCONJ
admet-130	83	9	s	s	PROPN
admet-130	83	10	-	-	PUNCT
admet-130	83	11	benzoyl	benzoyl	ADJ
admet-130	83	12	thiamine	thiamine	NOUN
admet-130	83	13	skin	skin	NOUN
admet-130	83	14	level	level	NOUN
admet-130	83	15	(	(	PUNCT
admet-130	83	16	stratum	stratum	PROPN
admet-130	83	17	corneum	corneum	NOUN
admet-130	83	18	removed	remove	VERB
admet-130	83	19	)	)	PUNCT
admet-130	83	20	was	be	AUX
admet-130	83	21	1.64	1.64	NUM
admet-130	83	22	nmol	nmol	NOUN
admet-130	83	23	/	/	SYM
admet-130	83	24	g	g	PROPN
admet-130	83	25	and	and	CCONJ
admet-130	83	26	1,492.33	1,492.33	NUM
admet-130	83	27	nmol	nmol	NOUN
admet-130	83	28	/	/	SYM
admet-130	83	29	g	g	NOUN
admet-130	83	30	respectively	respectively	ADV
admet-130	83	31	.	.	PUNCT
admet-130	84	1	concomitant	concomitant	ADJ
admet-130	84	2	with	with	ADP
admet-130	84	3	these	these	DET
admet-130	84	4	changes	change	NOUN
admet-130	84	5	,	,	PUNCT
admet-130	84	6	the	the	DET
admet-130	84	7	thiamine	thiamine	NOUN
admet-130	84	8	level	level	NOUN
admet-130	84	9	increased	increase	VERB
admet-130	84	10	from	from	ADP
admet-130	84	11	0.32	0.32	NUM
admet-130	84	12	nmol	nmol	NOUN
admet-130	84	13	/	/	SYM
admet-130	84	14	g	g	NOUN
admet-130	84	15	to	to	ADP
admet-130	84	16	809.25	809.25	NUM
admet-130	84	17	nmol	nmol	NOUN
admet-130	84	18	/	/	SYM
admet-130	84	19	g	g	NOUN
admet-130	84	20	,	,	PUNCT
admet-130	84	21	resulting	result	VERB
admet-130	84	22	in	in	ADP
admet-130	84	23	a	a	DET
admet-130	84	24	2,500	2,500	NUM
admet-130	84	25	-	-	ADJ
admet-130	84	26	fold	fold	ADJ
admet-130	84	27	enhancement	enhancement	NOUN
admet-130	84	28	in	in	ADP
admet-130	84	29	treated	treat	VERB
admet-130	84	30	animals	animal	NOUN
admet-130	84	31	.	.	PUNCT
admet-130	85	1	the	the	DET
admet-130	85	2	results	result	NOUN
admet-130	85	3	of	of	ADP
admet-130	85	4	the	the	DET
admet-130	85	5	accumulation	accumulation	NOUN
admet-130	85	6	of	of	ADP
admet-130	85	7	thiamine	thiamine	NOUN
admet-130	85	8	and	and	CCONJ
admet-130	85	9	thiamine	thiamine	NOUN
admet-130	85	10	derivatives	derivative	NOUN
admet-130	85	11	in	in	ADP
admet-130	85	12	the	the	DET
admet-130	85	13	skin	skin	NOUN
admet-130	85	14	tissue	tissue	NOUN
admet-130	85	15	located	locate	VERB
admet-130	85	16	under	under	ADP
admet-130	85	17	the	the	DET
admet-130	85	18	application	application	NOUN
admet-130	85	19	site	site	NOUN
admet-130	85	20	after	after	SCONJ
admet-130	85	21	24	24	NUM
admet-130	85	22	h	h	NOUN
admet-130	85	23	treatment	treatment	NOUN
admet-130	85	24	with	with	ADP
admet-130	85	25	the	the	DET
admet-130	85	26	5	5	NUM
admet-130	85	27	%	%	NOUN
admet-130	85	28	microcrystalline	microcrystalline	NOUN
admet-130	85	29	formulation	formulation	NOUN
admet-130	85	30	are	be	AUX
admet-130	85	31	summarized	summarize	VERB
admet-130	85	32	in	in	ADP
admet-130	85	33	figure	figure	NOUN
admet-130	85	34	3b	3b	NUM
admet-130	85	35	.	.	PUNCT
admet-130	86	1	similarly	similarly	ADV
admet-130	86	2	to	to	ADP
admet-130	86	3	the	the	DET
admet-130	86	4	treatment	treatment	NOUN
admet-130	86	5	with	with	ADP
admet-130	86	6	solubilized	solubilize	VERB
admet-130	86	7	3	3	NUM
admet-130	86	8	%	%	NOUN
admet-130	86	9	benfotiamine	benfotiamine	ADJ
admet-130	86	10	formulation	formulation	NOUN
admet-130	86	11	,	,	PUNCT
admet-130	86	12	we	we	PRON
admet-130	86	13	observed	observe	VERB
admet-130	86	14	no	no	DET
admet-130	86	15	obvious	obvious	ADJ
admet-130	86	16	change	change	NOUN
admet-130	86	17	of	of	ADP
admet-130	86	18	tdp	tdp	NOUN
admet-130	86	19	and	and	CCONJ
admet-130	86	20	tmp	tmp	NOUN
admet-130	86	21	levels	level	NOUN
admet-130	86	22	compared	compare	VERB
admet-130	86	23	to	to	ADP
admet-130	86	24	controls	control	NOUN
admet-130	86	25	over	over	ADP
admet-130	86	26	the	the	DET
admet-130	86	27	24	24	NUM
admet-130	86	28	hour	hour	NOUN
admet-130	86	29	period	period	NOUN
admet-130	86	30	.	.	PUNCT
admet-130	87	1	the	the	DET
admet-130	87	2	level	level	NOUN
admet-130	87	3	of	of	ADP
admet-130	87	4	benfotiamine	benfotiamine	PROPN
admet-130	87	5	appeared	appear	VERB
admet-130	87	6	low	low	ADJ
admet-130	87	7	,	,	PUNCT
admet-130	87	8	however	however	ADV
admet-130	87	9	,	,	PUNCT
admet-130	87	10	there	there	PRON
admet-130	87	11	was	be	VERB
admet-130	87	12	a	a	DET
admet-130	87	13	drastic	drastic	ADJ
admet-130	87	14	rise	rise	NOUN
admet-130	87	15	in	in	ADP
admet-130	87	16	s	s	ADJ
admet-130	87	17	-	-	PUNCT
admet-130	87	18	benzoyl	benzoyl	ADJ
admet-130	87	19	thiamine	thiamine	NOUN
admet-130	87	20	and	and	CCONJ
admet-130	87	21	thiamine	thiamine	NOUN
admet-130	87	22	levels	level	NOUN
admet-130	87	23	.	.	PUNCT
admet-130	88	1	concomitantly	concomitantly	ADV
admet-130	88	2	,	,	PUNCT
admet-130	88	3	the	the	DET
admet-130	88	4	thiamine	thiamine	NOUN
admet-130	88	5	level	level	NOUN
admet-130	88	6	increased	increase	VERB
admet-130	88	7	from	from	ADP
admet-130	88	8	0.32	0.32	NUM
admet-130	88	9	nmol	nmol	NOUN
admet-130	88	10	/	/	SYM
admet-130	88	11	g	g	NOUN
admet-130	88	12	to	to	ADP
admet-130	88	13	2,538.29	2,538.29	NUM
admet-130	88	14	nmol	nmol	NOUN
admet-130	88	15	/	/	SYM
admet-130	88	16	g	g	NOUN
admet-130	88	17	at	at	ADP
admet-130	88	18	t	t	NOUN
admet-130	88	19	=	=	NUM
admet-130	88	20	24	24	NUM
admet-130	88	21	hours	hour	NOUN
admet-130	88	22	that	that	PRON
admet-130	88	23	is	be	AUX
admet-130	88	24	a	a	DET
admet-130	88	25	7,880	7,880	NUM
admet-130	88	26	-	-	ADJ
admet-130	88	27	fold	fold	ADJ
admet-130	88	28	increase	increase	NOUN
admet-130	88	29	in	in	ADP
admet-130	88	30	treated	treat	VERB
admet-130	88	31	animals	animal	NOUN
admet-130	88	32	.	.	PUNCT
admet-130	89	1	we	we	PRON
admet-130	89	2	could	could	AUX
admet-130	89	3	not	not	PART
admet-130	89	4	determine	determine	VERB
admet-130	89	5	the	the	DET
admet-130	89	6	significance	significance	NOUN
admet-130	89	7	of	of	ADP
admet-130	89	8	the	the	DET
admet-130	89	9	increase	increase	NOUN
admet-130	89	10	in	in	ADP
admet-130	89	11	skin	skin	NOUN
admet-130	89	12	tissue	tissue	NOUN
admet-130	89	13	thiamine	thiamine	NOUN
admet-130	89	14	level	level	NOUN
admet-130	89	15	after	after	ADP
admet-130	89	16	24	24	NUM
admet-130	89	17	hrs	hrs	NOUN
admet-130	89	18	with	with	ADP
admet-130	89	19	treatment	treatment	NOUN
admet-130	89	20	of	of	ADP
admet-130	89	21	3	3	NUM
admet-130	89	22	%	%	NOUN
admet-130	89	23	solubilized	solubilize	VERB
admet-130	89	24	benfotiamine	benfotiamine	ADJ
admet-130	89	25	formulation	formulation	NOUN
admet-130	89	26	due	due	ADP
admet-130	89	27	to	to	ADP
admet-130	89	28	the	the	DET
admet-130	89	29	limited	limited	ADJ
admet-130	89	30	number	number	NOUN
admet-130	89	31	of	of	ADP
admet-130	89	32	animal	animal	NOUN
admet-130	89	33	subjects	subject	NOUN
admet-130	89	34	involved	involve	VERB
admet-130	89	35	in	in	ADP
admet-130	89	36	this	this	DET
admet-130	89	37	experiment	experiment	NOUN
admet-130	89	38	(	(	PUNCT
admet-130	89	39	n=2	n=2	ADV
admet-130	89	40	)	)	PUNCT
admet-130	89	41	,	,	PUNCT
admet-130	89	42	however	however	ADV
admet-130	89	43	,	,	PUNCT
admet-130	89	44	the	the	DET
admet-130	89	45	treatment	treatment	NOUN
admet-130	89	46	with	with	ADP
admet-130	89	47	the	the	DET
admet-130	89	48	5	5	NUM
admet-130	89	49	%	%	NOUN
admet-130	89	50	microcrystalline	microcrystalline	NOUN
admet-130	89	51	benfotiamine	benfotiamine	ADJ
admet-130	89	52	cream	cream	NOUN
admet-130	89	53	formulation	formulation	NOUN
admet-130	89	54	resulted	result	VERB
admet-130	89	55	in	in	ADP
admet-130	89	56	more	more	ADV
admet-130	89	57	robust	robust	ADJ
admet-130	89	58	enhancement	enhancement	NOUN
admet-130	89	59	in	in	ADP
admet-130	89	60	skin	skin	NOUN
admet-130	89	61	tissue	tissue	NOUN
admet-130	89	62	thiamine	thiamine	NOUN
admet-130	89	63	level	level	NOUN
admet-130	89	64	and	and	CCONJ
admet-130	89	65	this	this	DET
admet-130	89	66	value	value	NOUN
admet-130	89	67	appeared	appear	VERB
admet-130	89	68	significant	significant	ADJ
admet-130	89	69	when	when	SCONJ
admet-130	89	70	compared	compare	VERB
admet-130	89	71	to	to	ADP
admet-130	89	72	non	non	ADJ
admet-130	89	73	-	-	ADJ
admet-130	89	74	treated	treat	VERB
admet-130	89	75	control	control	NOUN
admet-130	89	76	(	(	PUNCT
admet-130	89	77	p=0.03	p=0.03	ADJ
admet-130	89	78	)	)	PUNCT
admet-130	89	79	(	(	PUNCT
admet-130	89	80	figure	figure	VERB
admet-130	89	81	3c	3c	NUM
admet-130	89	82	)	)	PUNCT
admet-130	89	83	.	.	PUNCT
admet-130	90	1	admet	admet	PROPN
admet-130	90	2	&	&	CCONJ
admet-130	90	3	dmpk	dmpk	PROPN
admet-130	90	4	2(4	2(4	NUM
admet-130	90	5	)	)	PUNCT
admet-130	90	6	(	(	PUNCT
admet-130	90	7	2014	2014	NUM
admet-130	90	8	)	)	PUNCT
admet-130	90	9	272	272	NUM
admet-130	90	10	-	-	SYM
admet-130	90	11	281	281	NUM
admet-130	90	12	transderamal	transderamal	ADJ
admet-130	90	13	delivery	delivery	NOUN
admet-130	90	14	of	of	ADP
admet-130	90	15	benfotiamine	benfotiamine	ADJ
admet-130	90	16	in	in	ADP
admet-130	90	17	an	an	DET
admet-130	90	18	animal	animal	NOUN
admet-130	90	19	model	model	NOUN
admet-130	90	20	doi	doi	NOUN
admet-130	90	21	:	:	PUNCT
admet-130	90	22	10.5599	10.5599	NUM
admet-130	90	23	/	/	SYM
admet-130	90	24	admet.2.4.130	admet.2.4.130	ADP
admet-130	90	25	277	277	NUM
admet-130	90	26	figure	figure	NOUN
admet-130	90	27	3	3	NUM
admet-130	90	28	.	.	PUNCT
admet-130	91	1	a	a	PRON
admet-130	91	2	;	;	PUNCT
admet-130	91	3	concentration	concentration	NOUN
admet-130	91	4	of	of	ADP
admet-130	91	5	bc	bc	PROPN
admet-130	91	6	-	-	PUNCT
admet-130	91	7	dn-01	dn-01	NOUN
admet-130	91	8	and	and	CCONJ
admet-130	91	9	metabolites	metabolite	NOUN
admet-130	91	10	in	in	ADP
admet-130	91	11	skin	skin	NOUN
admet-130	91	12	tissue	tissue	NOUN
admet-130	91	13	24	24	NUM
admet-130	91	14	h	h	NOUN
admet-130	91	15	after	after	ADP
admet-130	91	16	15	15	NUM
admet-130	91	17	mg	mg	ADJ
admet-130	91	18	topical	topical	ADJ
admet-130	91	19	application	application	NOUN
admet-130	91	20	of	of	ADP
admet-130	91	21	bc	bc	PROPN
admet-130	91	22	-	-	PUNCT
admet-130	91	23	dn-01	dn-01	ADV
admet-130	91	24	(	(	PUNCT
admet-130	91	25	solubilized	solubilize	VERB
admet-130	91	26	)	)	PUNCT
admet-130	91	27	.	.	PUNCT
admet-130	92	1	analysis	analysis	NOUN
admet-130	92	2	of	of	ADP
admet-130	92	3	the	the	DET
admet-130	92	4	content	content	NOUN
admet-130	92	5	of	of	ADP
admet-130	92	6	bc	bc	PROPN
admet-130	92	7	-	-	PUNCT
admet-130	92	8	dn-01	dn-01	NOUN
admet-130	92	9	in	in	ADP
admet-130	92	10	skin	skin	NOUN
admet-130	92	11	tissue	tissue	NOUN
admet-130	92	12	following	follow	VERB
admet-130	92	13	a	a	DET
admet-130	92	14	single	single	ADJ
admet-130	92	15	application	application	NOUN
admet-130	92	16	of	of	ADP
admet-130	92	17	15	15	NUM
admet-130	92	18	mg	mg	NOUN
admet-130	92	19	of	of	ADP
admet-130	92	20	solubilized	solubilize	VERB
admet-130	92	21	bc	bc	NOUN
admet-130	92	22	-	-	NOUN
admet-130	92	23	dn-01	dn-01	NOUN
admet-130	92	24	at	at	ADP
admet-130	92	25	t=0	t=0	PROPN
admet-130	92	26	for	for	ADP
admet-130	92	27	the	the	DET
admet-130	92	28	presence	presence	NOUN
admet-130	92	29	of	of	ADP
admet-130	92	30	bc	bc	PROPN
admet-130	92	31	-	-	PUNCT
admet-130	92	32	dn-01	dn-01	NOUN
admet-130	92	33	,	,	PUNCT
admet-130	92	34	its	its	PRON
admet-130	92	35	dephosphorylated	dephosphorylate	VERB
admet-130	92	36	intermediate	intermediate	ADJ
admet-130	92	37	metabolite	metabolite	NOUN
admet-130	92	38	(	(	PUNCT
admet-130	92	39	sbt	sbt	PROPN
admet-130	92	40	)	)	PUNCT
admet-130	92	41	,	,	PUNCT
admet-130	92	42	and	and	CCONJ
admet-130	92	43	thiamine	thiamine	NOUN
admet-130	92	44	(	(	PUNCT
admet-130	92	45	t	t	NOUN
admet-130	92	46	)	)	PUNCT
admet-130	92	47	,	,	PUNCT
admet-130	92	48	thiamine	thiamine	NOUN
admet-130	92	49	diphosphate	diphosphate	PROPN
admet-130	92	50	(	(	PUNCT
admet-130	92	51	tdp	tdp	NOUN
admet-130	92	52	)	)	PUNCT
admet-130	92	53	and	and	CCONJ
admet-130	92	54	thiamine	thiamine	NOUN
admet-130	92	55	monophosphate	monophosphate	NOUN
admet-130	92	56	(	(	PUNCT
admet-130	92	57	tmp	tmp	NOUN
admet-130	92	58	)	)	PUNCT
admet-130	92	59	.	.	PUNCT
admet-130	93	1	in	in	ADP
admet-130	93	2	addition	addition	NOUN
admet-130	93	3	,	,	PUNCT
admet-130	93	4	control	control	NOUN
admet-130	93	5	levels	level	NOUN
admet-130	93	6	of	of	ADP
admet-130	93	7	thiamine	thiamine	NOUN
admet-130	93	8	from	from	ADP
admet-130	93	9	untreated	untreated	ADJ
admet-130	93	10	skin	skin	NOUN
admet-130	93	11	were	be	AUX
admet-130	93	12	analyzed	analyze	VERB
admet-130	93	13	and	and	CCONJ
admet-130	93	14	graphed	graph	VERB
admet-130	93	15	.	.	PUNCT
admet-130	94	1	n=3	n=3	PUNCT
admet-130	94	2	for	for	ADP
admet-130	94	3	control	control	NOUN
admet-130	94	4	,	,	PUNCT
admet-130	94	5	bc	bc	PROPN
admet-130	94	6	-	-	PUNCT
admet-130	94	7	dn-01	dn-01	NOUN
admet-130	94	8	,	,	PUNCT
admet-130	94	9	tdp	tdp	NOUN
admet-130	94	10	and	and	CCONJ
admet-130	94	11	tmp	tmp	VERB
admet-130	94	12	in	in	ADP
admet-130	94	13	skin	skin	NOUN
admet-130	94	14	tissue	tissue	NOUN
admet-130	94	15	samples	sample	NOUN
admet-130	94	16	.	.	PUNCT
admet-130	94	17	n=2	n=2	X
admet-130	94	18	for	for	ADP
admet-130	94	19	determination	determination	NOUN
admet-130	94	20	of	of	ADP
admet-130	94	21	sbt	sbt	PROPN
admet-130	94	22	and	and	CCONJ
admet-130	94	23	t	t	PROPN
admet-130	94	24	in	in	ADP
admet-130	94	25	skin	skin	NOUN
admet-130	94	26	tissue	tissue	NOUN
admet-130	94	27	samples	sample	NOUN
admet-130	94	28	.	.	PUNCT
admet-130	95	1	b	b	X
admet-130	95	2	;	;	PUNCT
admet-130	95	3	concentration	concentration	NOUN
admet-130	95	4	of	of	ADP
admet-130	95	5	bc	bc	PROPN
admet-130	95	6	-	-	PUNCT
admet-130	95	7	dn-01	dn-01	NOUN
admet-130	95	8	and	and	CCONJ
admet-130	95	9	metabolites	metabolite	NOUN
admet-130	95	10	in	in	ADP
admet-130	95	11	skin	skin	NOUN
admet-130	95	12	tissue	tissue	NOUN
admet-130	95	13	24	24	NUM
admet-130	95	14	h	h	NOUN
admet-130	95	15	after	after	ADP
admet-130	95	16	25	25	NUM
admet-130	95	17	mg	mg	ADJ
admet-130	95	18	topical	topical	ADJ
admet-130	95	19	application	application	NOUN
admet-130	95	20	of	of	ADP
admet-130	95	21	bc	bc	PROPN
admet-130	95	22	-	-	PUNCT
admet-130	95	23	dn-01	dn-01	NOUN
admet-130	95	24	(	(	PUNCT
admet-130	95	25	suspension	suspension	NOUN
admet-130	95	26	)	)	PUNCT
admet-130	95	27	.	.	PUNCT
admet-130	96	1	analysis	analysis	NOUN
admet-130	96	2	of	of	ADP
admet-130	96	3	the	the	DET
admet-130	96	4	content	content	NOUN
admet-130	96	5	of	of	ADP
admet-130	96	6	bc	bc	PROPN
admet-130	96	7	-	-	PROPN
admet-130	96	8	dn01	dn01	PROPN
admet-130	96	9	in	in	ADP
admet-130	96	10	skin	skin	NOUN
admet-130	96	11	tissue	tissue	NOUN
admet-130	96	12	following	follow	VERB
admet-130	96	13	a	a	DET
admet-130	96	14	single	single	ADJ
admet-130	96	15	application	application	NOUN
admet-130	96	16	of	of	ADP
admet-130	96	17	25	25	NUM
admet-130	96	18	mg	mg	NOUN
admet-130	96	19	of	of	ADP
admet-130	96	20	suspended	suspend	VERB
admet-130	96	21	form	form	NOUN
admet-130	96	22	of	of	ADP
admet-130	96	23	bc	bc	PROPN
admet-130	96	24	-	-	NOUN
admet-130	96	25	dn-01	dn-01	NOUN
admet-130	96	26	at	at	ADP
admet-130	96	27	t=0	t=0	PROPN
admet-130	96	28	for	for	ADP
admet-130	96	29	the	the	DET
admet-130	96	30	presence	presence	NOUN
admet-130	96	31	of	of	ADP
admet-130	96	32	bc	bc	PROPN
admet-130	96	33	-	-	PUNCT
admet-130	96	34	dn-01	dn-01	NOUN
admet-130	96	35	,	,	PUNCT
admet-130	96	36	its	its	PRON
admet-130	96	37	dephosphorylated	dephosphorylate	VERB
admet-130	96	38	intermediate	intermediate	ADJ
admet-130	96	39	metabolite	metabolite	NOUN
admet-130	96	40	(	(	PUNCT
admet-130	96	41	sbt	sbt	PROPN
admet-130	96	42	)	)	PUNCT
admet-130	96	43	,	,	PUNCT
admet-130	96	44	and	and	CCONJ
admet-130	96	45	the	the	DET
admet-130	96	46	thiamine	thiamine	NOUN
admet-130	96	47	(	(	PUNCT
admet-130	96	48	t	t	NOUN
admet-130	96	49	)	)	PUNCT
admet-130	96	50	,	,	PUNCT
admet-130	96	51	thiamine	thiamine	NOUN
admet-130	96	52	diphosphate	diphosphate	PROPN
admet-130	96	53	(	(	PUNCT
admet-130	96	54	tdp	tdp	NOUN
admet-130	96	55	)	)	PUNCT
admet-130	96	56	and	and	CCONJ
admet-130	96	57	thiamine	thiamine	NOUN
admet-130	96	58	monophosphate	monophosphate	NOUN
admet-130	96	59	(	(	PUNCT
admet-130	96	60	tmp	tmp	NOUN
admet-130	96	61	)	)	PUNCT
admet-130	96	62	.	.	PUNCT
admet-130	97	1	in	in	ADP
admet-130	97	2	addition	addition	NOUN
admet-130	97	3	,	,	PUNCT
admet-130	97	4	control	control	NOUN
admet-130	97	5	levels	level	NOUN
admet-130	97	6	of	of	ADP
admet-130	97	7	thiamine	thiamine	NOUN
admet-130	97	8	from	from	ADP
admet-130	97	9	untreated	untreated	ADJ
admet-130	97	10	skin	skin	NOUN
admet-130	97	11	were	be	AUX
admet-130	97	12	analyzed	analyze	VERB
admet-130	97	13	and	and	CCONJ
admet-130	97	14	graphed	graph	VERB
admet-130	97	15	;	;	PUNCT
admet-130	97	16	n=3	n=3	PUNCT
admet-130	97	17	for	for	ADP
admet-130	97	18	skin	skin	NOUN
admet-130	97	19	.	.	PUNCT
admet-130	98	1	c	c	X
admet-130	98	2	;	;	PUNCT
admet-130	98	3	thiamine	thiamine	NOUN
admet-130	98	4	levels	level	NOUN
admet-130	98	5	in	in	ADP
admet-130	98	6	the	the	DET
admet-130	98	7	skin	skin	NOUN
admet-130	98	8	after	after	ADP
admet-130	98	9	24	24	NUM
admet-130	98	10	h	h	NOUN
admet-130	98	11	with	with	ADP
admet-130	98	12	treatment	treatment	NOUN
admet-130	98	13	of	of	ADP
admet-130	98	14	3	3	NUM
admet-130	98	15	%	%	NOUN
admet-130	98	16	bc	bc	PROPN
admet-130	98	17	-	-	NOUN
admet-130	98	18	dn-01	dn-01	NOUN
admet-130	98	19	and	and	CCONJ
admet-130	98	20	5	5	NUM
admet-130	98	21	%	%	NOUN
admet-130	98	22	bc	bc	PROPN
admet-130	98	23	-	-	PUNCT
admet-130	98	24	dn-01	dn-01	NOUN
admet-130	98	25	.	.	PUNCT
admet-130	99	1	numbers	number	NOUN
admet-130	99	2	in	in	ADP
admet-130	99	3	red	red	ADJ
admet-130	99	4	are	be	AUX
admet-130	99	5	mean	mean	ADJ
admet-130	99	6	values	value	NOUN
admet-130	99	7	from	from	ADP
admet-130	99	8	independent	independent	ADJ
admet-130	99	9	determinations	determination	NOUN
admet-130	99	10	as	as	SCONJ
admet-130	99	11	indicated	indicate	VERB
admet-130	99	12	in	in	ADP
admet-130	99	13	a	a	DET
admet-130	99	14	and	and	CCONJ
admet-130	99	15	b.	b.	PROPN
admet-130	99	16	bc	bc	PROPN
admet-130	99	17	-	-	PUNCT
admet-130	99	18	dn-01	dn-01	ADJ
admet-130	99	19	sbt	sbt	PROPN
admet-130	99	20	t	t	PROPN
admet-130	99	21	tdp	tdp	NOUN
admet-130	99	22	tmp	tmp	NOUN
admet-130	99	23	c	c	NOUN
admet-130	99	24	o	o	NOUN
admet-130	99	25	n	n	ADP
admet-130	99	26	c	c	NOUN
admet-130	99	27	e	e	X
admet-130	99	28	n	n	X
admet-130	99	29	tr	tr	DET
admet-130	99	30	a	a	DET
admet-130	99	31	ti	ti	NOUN
admet-130	99	32	o	o	NOUN
admet-130	100	1	n	n	NOUN
admet-130	101	1	i	i	PRON
admet-130	101	2	n	n	NOUN
admet-130	101	3	s	s	PART
admet-130	101	4	k	k	X
admet-130	101	5	in	in	ADP
admet-130	101	6	(	(	PUNCT
admet-130	101	7	n	n	NOUN
admet-130	101	8	m	m	NOUN
admet-130	101	9	o	o	NOUN
admet-130	101	10	l/	l/	NOUN
admet-130	101	11	g	g	PROPN
admet-130	101	12	)	)	PUNCT
admet-130	101	13	0	0	NUM
admet-130	102	1	1000	1000	NUM
admet-130	102	2	2000	2000	NUM
admet-130	102	3	3000	3000	NUM
admet-130	102	4	4000	4000	NUM
admet-130	102	5	6.51	6.51	NUM
admet-130	102	6	1875.19	1875.19	NUM
admet-130	102	7	2538.29	2538.29	NUM
admet-130	102	8	0.06	0.06	NUM
admet-130	102	9	1.03	1.03	NUM
admet-130	102	10	bc	bc	VERB
admet-130	102	11	-	-	PUNCT
admet-130	102	12	dn-01	dn-01	ADJ
admet-130	102	13	sbt	sbt	PROPN
admet-130	102	14	t	t	PROPN
admet-130	102	15	tdp	tdp	NOUN
admet-130	102	16	tmp	tmp	NOUN
admet-130	102	17	c	c	NOUN
admet-130	102	18	o	o	NOUN
admet-130	102	19	n	n	ADP
admet-130	102	20	c	c	NOUN
admet-130	102	21	e	e	X
admet-130	102	22	n	n	X
admet-130	102	23	tr	tr	DET
admet-130	102	24	a	a	DET
admet-130	102	25	ti	ti	NOUN
admet-130	102	26	o	o	NOUN
admet-130	103	1	n	n	NOUN
admet-130	104	1	i	i	PRON
admet-130	104	2	n	n	NOUN
admet-130	104	3	s	s	PART
admet-130	104	4	k	k	X
admet-130	104	5	in	in	ADP
admet-130	104	6	(	(	PUNCT
admet-130	104	7	n	n	NOUN
admet-130	104	8	m	m	NOUN
admet-130	104	9	o	o	NOUN
admet-130	104	10	l/	l/	NOUN
admet-130	104	11	g	g	PROPN
admet-130	104	12	)	)	PUNCT
admet-130	104	13	0	0	NUM
admet-130	105	1	500	500	NUM
admet-130	105	2	1000	1000	NUM
admet-130	105	3	1500	1500	NUM
admet-130	105	4	2000	2000	NUM
admet-130	105	5	2500	2500	NUM
admet-130	105	6	1.64	1.64	NUM
admet-130	105	7	1492.33	1492.33	NUM
admet-130	105	8	809.25	809.25	NUM
admet-130	105	9	0.04	0.04	NUM
admet-130	105	10	0.56	0.56	NUM
admet-130	105	11	a	a	DET
admet-130	105	12	b	b	NOUN
admet-130	105	13	c	c	NOUN
admet-130	105	14	3	3	NUM
admet-130	105	15	%	%	NOUN
admet-130	105	16	bc	bc	ADJ
admet-130	105	17	-	-	NOUN
admet-130	105	18	dn-01	dn-01	ADJ
admet-130	105	19	5	5	NUM
admet-130	105	20	%	%	NOUN
admet-130	105	21	bc	bc	ADJ
admet-130	105	22	-	-	ADJ
admet-130	105	23	dn-01	dn-01	ADJ
admet-130	105	24	control	control	NOUN
admet-130	105	25	c	c	NOUN
admet-130	105	26	o	o	NOUN
admet-130	105	27	n	n	ADP
admet-130	105	28	c	c	NOUN
admet-130	105	29	e	e	X
admet-130	105	30	n	n	X
admet-130	105	31	tr	tr	DET
admet-130	105	32	a	a	DET
admet-130	105	33	ti	ti	NOUN
admet-130	105	34	o	o	NOUN
admet-130	106	1	n	n	NOUN
admet-130	107	1	i	i	PRON
admet-130	107	2	n	n	NOUN
admet-130	107	3	s	s	PART
admet-130	107	4	k	k	X
admet-130	107	5	in	in	ADP
admet-130	107	6	(	(	PUNCT
admet-130	107	7	n	n	NOUN
admet-130	107	8	m	m	NOUN
admet-130	107	9	o	o	NOUN
admet-130	107	10	l/	l/	NOUN
admet-130	107	11	g	g	PROPN
admet-130	107	12	)	)	PUNCT
admet-130	107	13	0	0	NUM
admet-130	108	1	1000	1000	NUM
admet-130	108	2	2000	2000	NUM
admet-130	108	3	3000	3000	NUM
admet-130	109	1	809.25	809.25	NUM
admet-130	109	2	2538.29	2538.29	NUM
admet-130	109	3	0.32	0.32	NUM
admet-130	109	4	b	b	PROPN
admet-130	109	5	c	c	PROPN
admet-130	109	6	varadi	varadi	PROPN
admet-130	109	7	et.al	et.al	PROPN
admet-130	109	8	.	.	PUNCT
admet-130	110	1	admet	admet	PROPN
admet-130	110	2	&	&	CCONJ
admet-130	110	3	dmpk	dmpk	PROPN
admet-130	110	4	2(4	2(4	NUM
admet-130	110	5	)	)	PUNCT
admet-130	110	6	(	(	PUNCT
admet-130	110	7	2014	2014	NUM
admet-130	110	8	)	)	PUNCT
admet-130	110	9	272	272	NUM
admet-130	110	10	-	-	SYM
admet-130	110	11	281	281	NUM
admet-130	110	12	278	278	NUM
admet-130	110	13	these	these	DET
admet-130	110	14	pharmacokinetic	pharmacokinetic	ADJ
admet-130	110	15	studies	study	NOUN
admet-130	110	16	demonstrated	demonstrate	VERB
admet-130	110	17	that	that	SCONJ
admet-130	110	18	transdermally	transdermally	ADV
admet-130	110	19	-	-	PUNCT
admet-130	110	20	delivered	deliver	VERB
admet-130	110	21	benfotiamine	benfotiamine	NOUN
admet-130	110	22	is	be	AUX
admet-130	110	23	capable	capable	ADJ
admet-130	110	24	of	of	ADP
admet-130	110	25	serving	serve	VERB
admet-130	110	26	as	as	ADP
admet-130	110	27	a	a	DET
admet-130	110	28	prodrug	prodrug	NOUN
admet-130	110	29	for	for	ADP
admet-130	110	30	blood	blood	NOUN
admet-130	110	31	and	and	CCONJ
admet-130	110	32	intradermal	intradermal	ADJ
admet-130	110	33	thiamine	thiamine	NOUN
admet-130	110	34	production	production	NOUN
admet-130	110	35	.	.	PUNCT
admet-130	111	1	by	by	ADP
admet-130	111	2	making	make	VERB
admet-130	111	3	use	use	NOUN
admet-130	111	4	of	of	ADP
admet-130	111	5	alternative	alternative	ADJ
admet-130	111	6	drug	drug	NOUN
admet-130	111	7	forms	form	NOUN
admet-130	111	8	of	of	ADP
admet-130	111	9	the	the	DET
admet-130	111	10	benfotiamine	benfotiamine	NOUN
admet-130	111	11	as	as	ADV
admet-130	111	12	well	well	ADV
admet-130	111	13	as	as	ADP
admet-130	111	14	modifying	modify	VERB
admet-130	111	15	the	the	DET
admet-130	111	16	formulation	formulation	NOUN
admet-130	111	17	cofactors	cofactor	NOUN
admet-130	111	18	and	and	CCONJ
admet-130	111	19	solvents	solvent	NOUN
admet-130	111	20	we	we	PRON
admet-130	111	21	were	be	AUX
admet-130	111	22	able	able	ADJ
admet-130	111	23	to	to	PART
admet-130	111	24	achieve	achieve	VERB
admet-130	111	25	a	a	DET
admet-130	111	26	significant	significant	ADJ
admet-130	111	27	bioavailability	bioavailability	NOUN
admet-130	111	28	in	in	ADP
admet-130	111	29	the	the	DET
admet-130	111	30	target	target	NOUN
admet-130	111	31	tissue	tissue	NOUN
admet-130	111	32	of	of	ADP
admet-130	111	33	the	the	DET
admet-130	111	34	skin	skin	NOUN
admet-130	111	35	tissue	tissue	NOUN
admet-130	111	36	while	while	SCONJ
admet-130	111	37	also	also	ADV
admet-130	111	38	protecting	protect	VERB
admet-130	111	39	the	the	DET
admet-130	111	40	integrity	integrity	NOUN
admet-130	111	41	of	of	ADP
admet-130	111	42	the	the	DET
admet-130	111	43	molecule	molecule	NOUN
admet-130	111	44	for	for	ADP
admet-130	111	45	stability	stability	NOUN
admet-130	111	46	purposes	purpose	NOUN
admet-130	111	47	.	.	PUNCT
admet-130	112	1	our	our	PRON
admet-130	112	2	experimental	experimental	ADJ
admet-130	112	3	data	datum	NOUN
admet-130	112	4	from	from	ADP
admet-130	112	5	these	these	DET
admet-130	112	6	pharmacokinetic	pharmacokinetic	ADJ
admet-130	112	7	studies	study	NOUN
admet-130	112	8	with	with	ADP
admet-130	112	9	topical	topical	ADJ
admet-130	112	10	benfotiamine	benfotiamine	ADJ
admet-130	112	11	formulation	formulation	NOUN
admet-130	112	12	has	have	AUX
admet-130	112	13	demonstrated	demonstrate	VERB
admet-130	112	14	a	a	DET
admet-130	112	15	significant	significant	ADJ
admet-130	112	16	,	,	PUNCT
admet-130	112	17	~8000	~8000	NOUN
admet-130	112	18	-	-	ADJ
admet-130	112	19	fold	fold	ADJ
admet-130	112	20	,	,	PUNCT
admet-130	112	21	increase	increase	NOUN
admet-130	112	22	in	in	ADP
admet-130	112	23	the	the	DET
admet-130	112	24	level	level	NOUN
admet-130	112	25	of	of	ADP
admet-130	112	26	thiamine	thiamine	NOUN
admet-130	112	27	chemical	chemical	NOUN
admet-130	112	28	species	specie	NOUN
admet-130	112	29	in	in	ADP
admet-130	112	30	the	the	DET
admet-130	112	31	skin	skin	NOUN
admet-130	112	32	tissue	tissue	NOUN
admet-130	112	33	of	of	ADP
admet-130	112	34	animals	animal	NOUN
admet-130	112	35	receiving	receive	VERB
admet-130	112	36	a	a	DET
admet-130	112	37	single	single	ADJ
admet-130	112	38	25	25	NUM
admet-130	112	39	mg	mg	NOUN
admet-130	112	40	dose	dose	NOUN
admet-130	112	41	of	of	ADP
admet-130	112	42	topical	topical	ADJ
admet-130	112	43	benfotiamine	benfotiamine	NOUN
admet-130	112	44	at	at	ADP
admet-130	112	45	the	the	DET
admet-130	112	46	24	24	NUM
admet-130	112	47	hour	hour	NOUN
admet-130	112	48	time	time	NOUN
admet-130	112	49	point	point	NOUN
admet-130	112	50	following	follow	VERB
admet-130	112	51	the	the	DET
admet-130	112	52	application	application	NOUN
admet-130	112	53	.	.	PUNCT
admet-130	113	1	the	the	DET
admet-130	113	2	administration	administration	NOUN
admet-130	113	3	of	of	ADP
admet-130	113	4	benfotiamine	benfotiamine	PROPN
admet-130	113	5	as	as	ADP
admet-130	113	6	a	a	DET
admet-130	113	7	topical	topical	ADJ
admet-130	113	8	prodrug	prodrug	NOUN
admet-130	113	9	offers	offer	VERB
admet-130	113	10	several	several	ADJ
admet-130	113	11	advantages	advantage	NOUN
admet-130	113	12	over	over	ADP
admet-130	113	13	an	an	DET
admet-130	113	14	oral	oral	ADJ
admet-130	113	15	delivery	delivery	NOUN
admet-130	113	16	.	.	PUNCT
admet-130	114	1	firstly	firstly	ADV
admet-130	114	2	,	,	PUNCT
admet-130	114	3	benfotiamine	benfotiamine	PROPN
admet-130	114	4	contains	contain	VERB
admet-130	114	5	a	a	DET
admet-130	114	6	unique	unique	ADJ
admet-130	114	7	open	open	ADJ
admet-130	114	8	-	-	PUNCT
admet-130	114	9	ringed	ringed	ADJ
admet-130	114	10	structure	structure	NOUN
admet-130	114	11	giving	give	VERB
admet-130	114	12	the	the	DET
admet-130	114	13	molecule	molecule	NOUN
admet-130	114	14	a	a	DET
admet-130	114	15	significantly	significantly	ADV
admet-130	114	16	higher	high	ADJ
admet-130	114	17	bioavailability	bioavailability	NOUN
admet-130	114	18	index	index	NOUN
admet-130	114	19	compared	compare	VERB
admet-130	114	20	to	to	ADP
admet-130	114	21	thiamine	thiamine	NOUN
admet-130	114	22	[	[	X
admet-130	114	23	71	71	NUM
admet-130	114	24	-	-	SYM
admet-130	114	25	73	73	NUM
admet-130	114	26	]	]	PUNCT
admet-130	114	27	.	.	PUNCT
admet-130	115	1	thus	thus	ADV
admet-130	115	2	,	,	PUNCT
admet-130	115	3	the	the	DET
admet-130	115	4	first	first	ADJ
admet-130	115	5	pass	pass	NOUN
admet-130	115	6	liver	liver	NOUN
admet-130	115	7	metabolism	metabolism	NOUN
admet-130	115	8	as	as	ADV
admet-130	115	9	well	well	ADV
admet-130	115	10	as	as	ADP
admet-130	115	11	metabolic	metabolic	NOUN
admet-130	115	12	conversions	conversion	NOUN
admet-130	115	13	of	of	ADP
admet-130	115	14	the	the	DET
admet-130	115	15	drug	drug	NOUN
admet-130	115	16	crossing	cross	VERB
admet-130	115	17	the	the	DET
admet-130	115	18	intestinal	intestinal	ADJ
admet-130	115	19	wall	wall	NOUN
admet-130	115	20	will	will	AUX
admet-130	115	21	be	be	AUX
admet-130	115	22	avoided	avoid	VERB
admet-130	115	23	with	with	ADP
admet-130	115	24	a	a	DET
admet-130	115	25	topical	topical	ADJ
admet-130	115	26	administration	administration	NOUN
admet-130	115	27	.	.	PUNCT
admet-130	116	1	secondly	secondly	ADV
admet-130	116	2	,	,	PUNCT
admet-130	116	3	the	the	DET
admet-130	116	4	oral	oral	ADJ
admet-130	116	5	delivery	delivery	NOUN
admet-130	116	6	of	of	ADP
admet-130	116	7	benfotiamine	benfotiamine	PROPN
admet-130	116	8	has	have	AUX
admet-130	116	9	been	be	AUX
admet-130	116	10	shown	show	VERB
admet-130	116	11	to	to	PART
admet-130	116	12	significantly	significantly	ADV
admet-130	116	13	accumulate	accumulate	VERB
admet-130	116	14	in	in	ADP
admet-130	116	15	the	the	DET
admet-130	116	16	erythrocytes	erythrocyte	NOUN
admet-130	116	17	[	[	X
admet-130	116	18	74	74	NUM
admet-130	116	19	]	]	PUNCT
admet-130	116	20	and	and	CCONJ
admet-130	116	21	then	then	ADV
admet-130	116	22	in	in	ADP
admet-130	116	23	the	the	DET
admet-130	116	24	liver	liver	NOUN
admet-130	116	25	as	as	SCONJ
admet-130	116	26	opposed	oppose	VERB
admet-130	116	27	to	to	ADP
admet-130	116	28	being	be	AUX
admet-130	116	29	delivered	deliver	VERB
admet-130	116	30	in	in	ADP
admet-130	116	31	significant	significant	ADJ
admet-130	116	32	doses	dose	NOUN
admet-130	116	33	to	to	ADP
admet-130	116	34	the	the	DET
admet-130	116	35	peripheral	peripheral	ADJ
admet-130	116	36	nerves	nerve	NOUN
admet-130	116	37	in	in	ADP
admet-130	116	38	the	the	DET
admet-130	116	39	skin	skin	NOUN
admet-130	116	40	of	of	ADP
admet-130	116	41	the	the	DET
admet-130	116	42	legs	leg	NOUN
admet-130	116	43	and	and	CCONJ
admet-130	116	44	hands	hand	NOUN
admet-130	116	45	.	.	PUNCT
admet-130	117	1	topical	topical	ADJ
admet-130	117	2	delivery	delivery	NOUN
admet-130	117	3	of	of	ADP
admet-130	117	4	benfotiamine	benfotiamine	ADJ
admet-130	117	5	will	will	AUX
admet-130	117	6	concentrate	concentrate	VERB
admet-130	117	7	the	the	DET
admet-130	117	8	drug	drug	NOUN
admet-130	117	9	in	in	ADP
admet-130	117	10	the	the	DET
admet-130	117	11	target	target	NOUN
admet-130	117	12	tissues	tissue	NOUN
admet-130	117	13	immediately	immediately	ADV
admet-130	117	14	without	without	ADP
admet-130	117	15	dilution	dilution	NOUN
admet-130	117	16	.	.	PUNCT
admet-130	118	1	as	as	ADP
admet-130	118	2	a	a	DET
admet-130	118	3	result	result	NOUN
admet-130	118	4	,	,	PUNCT
admet-130	118	5	the	the	DET
admet-130	118	6	impact	impact	NOUN
admet-130	118	7	on	on	ADP
admet-130	118	8	the	the	DET
admet-130	118	9	damaged	damage	VERB
admet-130	118	10	cells	cell	NOUN
admet-130	118	11	and	and	CCONJ
admet-130	118	12	tissues	tissue	NOUN
admet-130	118	13	should	should	AUX
admet-130	118	14	respond	respond	VERB
admet-130	118	15	better	well	ADV
admet-130	118	16	than	than	ADP
admet-130	118	17	the	the	DET
admet-130	118	18	oral	oral	ADJ
admet-130	118	19	applications	application	NOUN
admet-130	118	20	.	.	PUNCT
admet-130	119	1	in	in	ADP
admet-130	119	2	contrast	contrast	NOUN
admet-130	119	3	to	to	ADP
admet-130	119	4	using	use	VERB
admet-130	119	5	thiamine	thiamine	NOUN
admet-130	119	6	as	as	SCONJ
admet-130	119	7	the	the	DET
admet-130	119	8	drug	drug	NOUN
admet-130	119	9	to	to	PART
admet-130	119	10	treat	treat	VERB
admet-130	119	11	diabetic	diabetic	ADJ
admet-130	119	12	peripheral	peripheral	ADJ
admet-130	119	13	neuropathy	neuropathy	ADJ
admet-130	119	14	,	,	PUNCT
admet-130	119	15	benfotiamine	benfotiamine	ADJ
admet-130	119	16	is	be	AUX
admet-130	119	17	a	a	DET
admet-130	119	18	chemical	chemical	ADJ
admet-130	119	19	analog	analog	NOUN
admet-130	119	20	of	of	ADP
admet-130	119	21	thiamine	thiamine	NOUN
admet-130	119	22	that	that	PRON
admet-130	119	23	is	be	AUX
admet-130	119	24	considerably	considerably	ADV
admet-130	119	25	more	more	ADV
admet-130	119	26	bioavailable	bioavailable	ADJ
admet-130	119	27	at	at	ADP
admet-130	119	28	the	the	DET
admet-130	119	29	systemic	systemic	ADJ
admet-130	119	30	as	as	ADV
admet-130	119	31	well	well	ADV
admet-130	119	32	as	as	ADP
admet-130	119	33	the	the	DET
admet-130	119	34	cellular	cellular	ADJ
admet-130	119	35	level	level	NOUN
admet-130	119	36	than	than	ADP
admet-130	119	37	thiamine	thiamine	NOUN
admet-130	119	38	.	.	PUNCT
admet-130	120	1	therefore	therefore	ADV
admet-130	120	2	,	,	PUNCT
admet-130	120	3	if	if	SCONJ
admet-130	120	4	administered	administer	VERB
admet-130	120	5	to	to	ADP
admet-130	120	6	patients	patient	NOUN
admet-130	120	7	with	with	ADP
admet-130	120	8	diabetic	diabetic	ADJ
admet-130	120	9	neuropathy	neuropathy	ADJ
admet-130	120	10	,	,	PUNCT
admet-130	120	11	topical	topical	ADJ
admet-130	120	12	benfotiamine	benfotiamine	NOUN
admet-130	120	13	should	should	AUX
admet-130	120	14	have	have	VERB
admet-130	120	15	a	a	DET
admet-130	120	16	favorable	favorable	ADJ
admet-130	120	17	efficacy	efficacy	NOUN
admet-130	120	18	profile	profile	NOUN
admet-130	120	19	through	through	ADP
admet-130	120	20	the	the	DET
admet-130	120	21	introduction	introduction	NOUN
admet-130	120	22	of	of	ADP
admet-130	120	23	greater	great	ADJ
admet-130	120	24	quantities	quantity	NOUN
admet-130	120	25	of	of	ADP
admet-130	120	26	thiamine	thiamine	NOUN
admet-130	120	27	into	into	ADP
admet-130	120	28	the	the	DET
admet-130	120	29	cell	cell	NOUN
admet-130	120	30	.	.	PUNCT
admet-130	121	1	thiamine	thiamine	ADJ
admet-130	121	2	cellular	cellular	ADJ
admet-130	121	3	absorption	absorption	NOUN
admet-130	121	4	derived	derive	VERB
admet-130	121	5	from	from	ADP
admet-130	121	6	orally	orally	ADV
admet-130	121	7	administered	administer	VERB
admet-130	121	8	benfotiamine	benfotiamine	PROPN
admet-130	121	9	is	be	AUX
admet-130	121	10	about	about	ADV
admet-130	121	11	five	five	NUM
admet-130	121	12	times	time	NOUN
admet-130	121	13	greater	great	ADJ
admet-130	121	14	than	than	ADP
admet-130	121	15	those	those	DET
admet-130	121	16	levels	level	NOUN
admet-130	121	17	obtained	obtain	VERB
admet-130	121	18	from	from	ADP
admet-130	121	19	conventional	conventional	ADJ
admet-130	121	20	thiamine	thiamine	NOUN
admet-130	121	21	supplements	supplement	NOUN
admet-130	121	22	[	[	X
admet-130	121	23	19,71	19,71	NUM
admet-130	121	24	-	-	SYM
admet-130	121	25	73	73	NUM
admet-130	121	26	]	]	PUNCT
admet-130	121	27	.	.	PUNCT
admet-130	122	1	this	this	DET
admet-130	122	2	differential	differential	ADJ
admet-130	122	3	bioavailability	bioavailability	NOUN
admet-130	122	4	is	be	AUX
admet-130	122	5	even	even	ADV
admet-130	122	6	greater	great	ADJ
admet-130	122	7	in	in	ADP
admet-130	122	8	the	the	DET
admet-130	122	9	brain	brain	NOUN
admet-130	122	10	and	and	CCONJ
admet-130	122	11	muscle	muscle	NOUN
admet-130	122	12	tissues	tissue	NOUN
admet-130	122	13	that	that	PRON
admet-130	122	14	yield	yield	VERB
admet-130	122	15	fiveto	fiveto	ADJ
admet-130	122	16	twenty	twenty	NUM
admet-130	122	17	-	-	PUNCT
admet-130	122	18	five	five	NUM
admet-130	122	19	-	-	NOUN
admet-130	122	20	fold	fold	VERB
admet-130	122	21	more	more	ADJ
admet-130	122	22	thiamine	thiamine	NOUN
admet-130	123	1	[	[	X
admet-130	123	2	22	22	NUM
admet-130	123	3	]	]	PUNCT
admet-130	123	4	after	after	ADP
admet-130	123	5	a	a	DET
admet-130	123	6	benfotiamine	benfotiamine	ADJ
admet-130	123	7	application	application	NOUN
admet-130	123	8	compared	compare	VERB
admet-130	123	9	to	to	ADP
admet-130	123	10	equivalent	equivalent	ADJ
admet-130	123	11	doses	dose	NOUN
admet-130	123	12	of	of	ADP
admet-130	123	13	thiamine	thiamine	NOUN
admet-130	123	14	.	.	PUNCT
admet-130	124	1	for	for	ADP
admet-130	124	2	benfotiamine	benfotiamine	ADJ
admet-130	124	3	given	give	VERB
admet-130	124	4	transdermally	transdermally	ADV
admet-130	124	5	,	,	PUNCT
admet-130	124	6	a	a	DET
admet-130	124	7	similar	similar	ADJ
admet-130	124	8	cascade	cascade	NOUN
admet-130	124	9	of	of	ADP
admet-130	124	10	biochemistry	biochemistry	NOUN
admet-130	124	11	occurs	occur	VERB
admet-130	124	12	with	with	ADP
admet-130	124	13	the	the	DET
admet-130	124	14	dephosphorylation	dephosphorylation	NOUN
admet-130	124	15	of	of	ADP
admet-130	124	16	the	the	DET
admet-130	124	17	native	native	ADJ
admet-130	124	18	benfotiamine	benfotiamine	ADJ
admet-130	124	19	catalyzed	catalyze	VERB
admet-130	124	20	by	by	ADP
admet-130	124	21	phosphatase	phosphatase	NOUN
admet-130	124	22	enzymes	enzyme	NOUN
admet-130	124	23	positioned	position	VERB
admet-130	124	24	on	on	ADP
admet-130	124	25	the	the	DET
admet-130	124	26	outside	outside	NOUN
admet-130	124	27	of	of	ADP
admet-130	124	28	epidermal	epidermal	ADJ
admet-130	124	29	cells	cell	NOUN
admet-130	124	30	producing	produce	VERB
admet-130	124	31	s	s	NOUN
admet-130	124	32	-	-	NOUN
admet-130	124	33	benzoylthiamine	benzoylthiamine	NOUN
admet-130	124	34	.	.	PUNCT
admet-130	125	1	once	once	ADV
admet-130	125	2	in	in	ADP
admet-130	125	3	this	this	DET
admet-130	125	4	form	form	NOUN
admet-130	125	5	,	,	PUNCT
admet-130	125	6	the	the	DET
admet-130	125	7	s	s	NOUN
admet-130	125	8	-	-	PUNCT
admet-130	125	9	benzoylthiamine	benzoylthiamine	NOUN
admet-130	125	10	prodrug	prodrug	NOUN
admet-130	125	11	follows	follow	VERB
admet-130	125	12	the	the	DET
admet-130	125	13	same	same	ADJ
admet-130	125	14	passive	passive	ADJ
admet-130	125	15	transport	transport	NOUN
admet-130	125	16	across	across	ADP
admet-130	125	17	the	the	DET
admet-130	125	18	membrane	membrane	NOUN
admet-130	125	19	of	of	ADP
admet-130	125	20	the	the	DET
admet-130	125	21	cells	cell	NOUN
admet-130	125	22	of	of	ADP
admet-130	125	23	the	the	DET
admet-130	125	24	epidermis	epidermis	NOUN
admet-130	125	25	and	and	CCONJ
admet-130	125	26	dermis	dermis	NOUN
admet-130	125	27	including	include	VERB
admet-130	125	28	those	those	PRON
admet-130	125	29	of	of	ADP
admet-130	125	30	the	the	DET
admet-130	125	31	schwann	schwann	PROPN
admet-130	125	32	cells	cell	NOUN
admet-130	125	33	and	and	CCONJ
admet-130	125	34	neurons	neuron	NOUN
admet-130	125	35	,	,	PUNCT
admet-130	125	36	delivering	deliver	VERB
admet-130	125	37	a	a	DET
admet-130	125	38	high	high	ADJ
admet-130	125	39	dose	dose	NOUN
admet-130	125	40	of	of	ADP
admet-130	125	41	the	the	DET
admet-130	125	42	prodrug	prodrug	NOUN
admet-130	125	43	and	and	CCONJ
admet-130	125	44	subsequently	subsequently	ADV
admet-130	125	45	the	the	DET
admet-130	125	46	thiamine	thiamine	NOUN
admet-130	125	47	to	to	ADP
admet-130	125	48	those	those	DET
admet-130	125	49	cells	cell	NOUN
admet-130	125	50	.	.	PUNCT
admet-130	126	1	the	the	DET
admet-130	126	2	thiamine	thiamine	NOUN
admet-130	126	3	diphosphate	diphosphate	PROPN
admet-130	126	4	produced	produce	VERB
admet-130	126	5	from	from	ADP
admet-130	126	6	the	the	DET
admet-130	126	7	elevated	elevated	ADJ
admet-130	126	8	thiamine	thiamine	NOUN
admet-130	126	9	activates	activate	VERB
admet-130	126	10	the	the	DET
admet-130	126	11	transketolase	transketolase	NOUN
admet-130	126	12	and	and	CCONJ
admet-130	126	13	the	the	DET
admet-130	126	14	pentose	pentose	NOUN
admet-130	126	15	phosphate	phosphate	NOUN
admet-130	126	16	pathway	pathway	NOUN
admet-130	126	17	,	,	PUNCT
admet-130	126	18	altering	alter	VERB
admet-130	126	19	the	the	DET
admet-130	126	20	glucose	glucose	NOUN
admet-130	126	21	metabolism	metabolism	NOUN
admet-130	126	22	to	to	PART
admet-130	126	23	reduce	reduce	VERB
admet-130	126	24	the	the	DET
admet-130	126	25	formation	formation	NOUN
admet-130	126	26	of	of	ADP
admet-130	126	27	ages	age	NOUN
admet-130	126	28	.	.	PUNCT
admet-130	127	1	reduction	reduction	NOUN
admet-130	127	2	of	of	ADP
admet-130	127	3	ages	age	NOUN
admet-130	127	4	in	in	ADP
admet-130	127	5	the	the	DET
admet-130	127	6	schwann	schwann	PROPN
admet-130	127	7	and	and	CCONJ
admet-130	127	8	neuronal	neuronal	ADJ
admet-130	127	9	cells	cell	NOUN
admet-130	127	10	reduces	reduce	VERB
admet-130	127	11	the	the	DET
admet-130	127	12	expression	expression	NOUN
admet-130	127	13	of	of	ADP
admet-130	127	14	neuropathy	neuropathy	ADJ
admet-130	127	15	symptoms	symptom	NOUN
admet-130	127	16	and	and	CCONJ
admet-130	127	17	also	also	ADV
admet-130	127	18	addresses	address	VERB
admet-130	127	19	the	the	DET
admet-130	127	20	base	base	NOUN
admet-130	127	21	etiology	etiology	NOUN
admet-130	127	22	of	of	ADP
admet-130	127	23	the	the	DET
admet-130	127	24	disease	disease	NOUN
admet-130	127	25	state	state	NOUN
admet-130	127	26	.	.	PUNCT
admet-130	128	1	conclusions	conclusion	NOUN
admet-130	128	2	conclusions	conclusion	NOUN
admet-130	128	3	from	from	ADP
admet-130	128	4	the	the	DET
admet-130	128	5	proof	proof	NOUN
admet-130	128	6	of	of	ADP
admet-130	128	7	concept	concept	NOUN
admet-130	128	8	study	study	NOUN
admet-130	128	9	in	in	ADP
admet-130	128	10	guinea	guinea	NOUN
admet-130	128	11	pigs	pig	NOUN
admet-130	128	12	is	be	AUX
admet-130	128	13	primarily	primarily	ADV
admet-130	128	14	that	that	SCONJ
admet-130	128	15	after	after	ADP
admet-130	128	16	single	single	ADJ
admet-130	128	17	topical	topical	ADJ
admet-130	128	18	application	application	NOUN
admet-130	128	19	of	of	ADP
admet-130	128	20	either	either	CCONJ
admet-130	128	21	a	a	DET
admet-130	128	22	solution	solution	NOUN
admet-130	128	23	form	form	NOUN
admet-130	128	24	of	of	ADP
admet-130	128	25	benfotiamine	benfotiamine	ADJ
admet-130	128	26	(	(	PUNCT
admet-130	128	27	15	15	NUM
admet-130	128	28	mg	mg	NOUN
admet-130	128	29	)	)	PUNCT
admet-130	128	30	or	or	CCONJ
admet-130	128	31	a	a	DET
admet-130	128	32	microcrystalline	microcrystalline	NOUN
admet-130	128	33	suspension	suspension	NOUN
admet-130	128	34	form	form	NOUN
admet-130	128	35	(	(	PUNCT
admet-130	128	36	25	25	NUM
admet-130	128	37	mg	mg	NOUN
admet-130	128	38	)	)	PUNCT
admet-130	128	39	we	we	PRON
admet-130	128	40	found	find	VERB
admet-130	128	41	considerable	considerable	ADJ
admet-130	128	42	increases	increase	NOUN
admet-130	128	43	of	of	ADP
admet-130	128	44	the	the	DET
admet-130	128	45	dephosphorylated	dephosphorylate	VERB
admet-130	128	46	benfotiamine	benfotiamine	ADJ
admet-130	128	47	(	(	PUNCT
admet-130	128	48	s	s	NOUN
admet-130	128	49	-	-	NOUN
admet-130	128	50	benzoylthiamine	benzoylthiamine	NOUN
admet-130	128	51	)	)	PUNCT
admet-130	128	52	in	in	ADP
admet-130	128	53	the	the	DET
admet-130	128	54	skin	skin	NOUN
admet-130	128	55	tissue	tissue	NOUN
admet-130	128	56	as	as	ADV
admet-130	128	57	well	well	ADV
admet-130	128	58	as	as	ADP
admet-130	128	59	significant	significant	ADJ
admet-130	128	60	increases	increase	NOUN
admet-130	128	61	in	in	ADP
admet-130	128	62	the	the	DET
admet-130	128	63	thiamine	thiamine	NOUN
admet-130	128	64	and	and	CCONJ
admet-130	128	65	thiamine	thiamine	NOUN
admet-130	128	66	phosphate	phosphate	NOUN
admet-130	128	67	pools	pool	NOUN
admet-130	128	68	compared	compare	VERB
admet-130	128	69	to	to	ADP
admet-130	128	70	control	control	VERB
admet-130	128	71	animals	animal	NOUN
admet-130	128	72	.	.	PUNCT
admet-130	129	1	the	the	DET
admet-130	129	2	presence	presence	NOUN
admet-130	129	3	of	of	ADP
admet-130	129	4	a	a	DET
admet-130	129	5	~8000x	~8000x	ADJ
admet-130	129	6	increase	increase	NOUN
admet-130	129	7	in	in	ADP
admet-130	129	8	thiamine	thiamine	NOUN
admet-130	129	9	and	and	CCONJ
admet-130	129	10	increase	increase	VERB
admet-130	129	11	in	in	ADP
admet-130	129	12	its	its	PRON
admet-130	129	13	phosphorylated	phosphorylate	VERB
admet-130	129	14	derivatives	derivative	NOUN
admet-130	129	15	in	in	ADP
admet-130	129	16	the	the	DET
admet-130	129	17	epidermis	epidermis	NOUN
admet-130	129	18	and	and	CCONJ
admet-130	129	19	dermis	dermis	NOUN
admet-130	129	20	tissue	tissue	NOUN
admet-130	129	21	of	of	ADP
admet-130	129	22	the	the	DET
admet-130	129	23	test	test	NOUN
admet-130	129	24	animals	animal	NOUN
admet-130	129	25	gives	give	VERB
admet-130	129	26	a	a	DET
admet-130	129	27	strong	strong	ADJ
admet-130	129	28	indication	indication	NOUN
admet-130	129	29	that	that	SCONJ
admet-130	129	30	the	the	DET
admet-130	129	31	topical	topical	ADJ
admet-130	129	32	treatment	treatment	NOUN
admet-130	129	33	with	with	ADP
admet-130	129	34	benfotiamine	benfotiamine	ADJ
admet-130	129	35	works	work	NOUN
admet-130	129	36	very	very	ADV
admet-130	129	37	well	well	ADV
admet-130	129	38	for	for	ADP
admet-130	129	39	the	the	DET
admet-130	129	40	desired	desire	VERB
admet-130	129	41	outcome	outcome	NOUN
admet-130	129	42	of	of	ADP
admet-130	129	43	producing	produce	VERB
admet-130	129	44	an	an	DET
admet-130	129	45	intracellular	intracellular	ADJ
admet-130	129	46	increase	increase	NOUN
admet-130	129	47	of	of	ADP
admet-130	129	48	the	the	DET
admet-130	129	49	activating	activating	ADJ
admet-130	129	50	cofactor	cofactor	NOUN
admet-130	129	51	pool	pool	NOUN
admet-130	129	52	for	for	ADP
admet-130	129	53	transketolase	transketolase	NOUN
admet-130	129	54	.	.	PUNCT
admet-130	130	1	subsequently	subsequently	ADV
admet-130	130	2	,	,	PUNCT
admet-130	130	3	it	it	PRON
admet-130	130	4	is	be	AUX
admet-130	130	5	reasonable	reasonable	ADJ
admet-130	130	6	to	to	PART
admet-130	130	7	conclude	conclude	VERB
admet-130	130	8	that	that	SCONJ
admet-130	130	9	this	this	DET
admet-130	130	10	metabolite	metabolite	NOUN
admet-130	130	11	admet	admet	PROPN
admet-130	130	12	&	&	CCONJ
admet-130	130	13	dmpk	dmpk	PROPN
admet-130	130	14	2(4	2(4	NUM
admet-130	130	15	)	)	PUNCT
admet-130	130	16	(	(	PUNCT
admet-130	130	17	2014	2014	NUM
admet-130	130	18	)	)	PUNCT
admet-130	130	19	272	272	NUM
admet-130	130	20	-	-	SYM
admet-130	130	21	281	281	NUM
admet-130	130	22	transderamal	transderamal	ADJ
admet-130	130	23	delivery	delivery	NOUN
admet-130	130	24	of	of	ADP
admet-130	130	25	benfotiamine	benfotiamine	ADJ
admet-130	130	26	in	in	ADP
admet-130	130	27	an	an	DET
admet-130	130	28	animal	animal	NOUN
admet-130	130	29	model	model	NOUN
admet-130	130	30	doi	doi	NOUN
admet-130	130	31	:	:	PUNCT
admet-130	130	32	10.5599	10.5599	NUM
admet-130	130	33	/	/	SYM
admet-130	130	34	admet.2.4.130	admet.2.4.130	ADP
admet-130	130	35	279	279	NUM
admet-130	130	36	level	level	NOUN
admet-130	130	37	increase	increase	NOUN
admet-130	130	38	,	,	PUNCT
admet-130	130	39	including	include	VERB
admet-130	130	40	tdp	tdp	NOUN
admet-130	130	41	,	,	PUNCT
admet-130	130	42	as	as	ADP
admet-130	130	43	a	a	DET
admet-130	130	44	function	function	NOUN
admet-130	130	45	of	of	ADP
admet-130	130	46	cellular	cellular	ADJ
admet-130	130	47	compartmentalization	compartmentalization	NOUN
admet-130	130	48	of	of	ADP
admet-130	130	49	metabolites	metabolite	NOUN
admet-130	130	50	and	and	CCONJ
admet-130	130	51	pools	pool	NOUN
admet-130	130	52	of	of	ADP
admet-130	130	53	the	the	DET
admet-130	130	54	thiamine	thiamine	NOUN
admet-130	130	55	derivatives	derivative	NOUN
admet-130	130	56	,	,	PUNCT
admet-130	130	57	will	will	AUX
admet-130	130	58	well	well	ADV
admet-130	130	59	serve	serve	VERB
admet-130	130	60	the	the	DET
admet-130	130	61	diabetic	diabetic	ADJ
admet-130	130	62	neuropathic	neuropathic	ADJ
admet-130	130	63	disease	disease	NOUN
admet-130	130	64	condition	condition	NOUN
admet-130	130	65	by	by	ADP
admet-130	130	66	activating	activate	VERB
admet-130	130	67	the	the	DET
admet-130	130	68	transketolase	transketolase	NOUN
admet-130	130	69	and	and	CCONJ
admet-130	130	70	activating	activate	VERB
admet-130	130	71	the	the	DET
admet-130	130	72	pentose	pentose	NOUN
admet-130	130	73	phosphate	phosphate	NOUN
admet-130	130	74	pathway	pathway	NOUN
admet-130	130	75	as	as	ADP
admet-130	130	76	an	an	DET
admet-130	130	77	alternative	alternative	ADJ
admet-130	130	78	mechanism	mechanism	NOUN
admet-130	130	79	to	to	PART
admet-130	130	80	metabolize	metabolize	VERB
admet-130	130	81	glucose	glucose	NOUN
admet-130	130	82	into	into	ADP
admet-130	130	83	harmless	harmless	ADJ
admet-130	130	84	end	end	NOUN
admet-130	130	85	-	-	PUNCT
admet-130	130	86	products	product	NOUN
admet-130	130	87	as	as	SCONJ
admet-130	130	88	opposed	oppose	VERB
admet-130	130	89	to	to	ADP
admet-130	130	90	the	the	DET
admet-130	130	91	continued	continue	VERB
admet-130	130	92	production	production	NOUN
admet-130	130	93	of	of	ADP
admet-130	130	94	advanced	advanced	ADJ
admet-130	130	95	glycation	glycation	NOUN
admet-130	130	96	endproducts	endproduct	NOUN
admet-130	130	97	.	.	PUNCT
admet-130	131	1	acknowledgements	acknowledgement	NOUN
admet-130	131	2	:	:	PUNCT
admet-130	131	3	this	this	DET
admet-130	131	4	work	work	NOUN
admet-130	131	5	was	be	AUX
admet-130	131	6	supported	support	VERB
admet-130	131	7	by	by	ADP
admet-130	131	8	funds	fund	NOUN
admet-130	131	9	from	from	ADP
admet-130	131	10	biochemics	biochemic	NOUN
admet-130	131	11	,	,	PUNCT
admet-130	131	12	inc	inc	PROPN
admet-130	131	13	.	.	PROPN
admet-130	131	14	references	reference	NOUN
admet-130	132	1	[	[	X
admet-130	132	2	1	1	NUM
admet-130	132	3	]	]	PUNCT
admet-130	132	4	m.	m.	NOUN
admet-130	132	5	brownlee	brownlee	PROPN
admet-130	132	6	,	,	PUNCT
admet-130	132	7	nature	nature	NOUN
admet-130	132	8	414	414	NUM
admet-130	132	9	(	(	PUNCT
admet-130	132	10	2001	2001	NUM
admet-130	132	11	)	)	PUNCT
admet-130	132	12	813	813	NUM
admet-130	132	13	-	-	SYM
admet-130	132	14	820	820	NUM
admet-130	132	15	.	.	PUNCT
admet-130	133	1	[	[	X
admet-130	133	2	2	2	X
admet-130	133	3	]	]	X
admet-130	133	4	h.p	h.p	PROPN
admet-130	133	5	.	.	PROPN
admet-130	133	6	hammes	hammes	PROPN
admet-130	133	7	,	,	PUNCT
admet-130	133	8	x.	x.	PROPN
admet-130	133	9	du	du	PROPN
admet-130	133	10	,	,	PUNCT
admet-130	133	11	d.	d.	PROPN
admet-130	133	12	edelstein	edelstein	PROPN
admet-130	133	13	,	,	PUNCT
admet-130	133	14	t.	t.	PROPN
admet-130	133	15	taguchi	taguchi	PROPN
admet-130	133	16	,	,	PUNCT
admet-130	133	17	t.	t.	PROPN
admet-130	133	18	matsumura	matsumura	ADJ
admet-130	133	19	,	,	PUNCT
admet-130	133	20	q	q	NOUN
admet-130	133	21	,	,	PUNCT
admet-130	133	22	ju	ju	PROPN
admet-130	133	23	,	,	PUNCT
admet-130	133	24	j.	j.	PROPN
admet-130	133	25	lin	lin	PROPN
admet-130	133	26	,	,	PUNCT
admet-130	133	27	a.	a.	NOUN
admet-130	133	28	bierhaus	bierhaus	PROPN
admet-130	133	29	,	,	PUNCT
admet-130	133	30	p.	p.	PROPN
admet-130	133	31	nawroth	nawroth	PROPN
admet-130	133	32	,	,	PUNCT
admet-130	133	33	d.	d.	PROPN
admet-130	133	34	hannak	hannak	PROPN
admet-130	133	35	,	,	PUNCT
admet-130	133	36	m.	m.	NOUN
admet-130	133	37	neumaier	neumaier	NOUN
admet-130	133	38	,	,	PUNCT
admet-130	133	39	r.	r.	PROPN
admet-130	133	40	bergfeld	bergfeld	PROPN
admet-130	133	41	,	,	PUNCT
admet-130	133	42	i.	i.	PROPN
admet-130	133	43	giardino	giardino	PROPN
admet-130	133	44	,	,	PUNCT
admet-130	133	45	m.	m.	NOUN
admet-130	133	46	brownlee	brownlee	PROPN
admet-130	133	47	,	,	PUNCT
admet-130	133	48	nature	nature	NOUN
admet-130	133	49	med	me	VERB
admet-130	133	50	.	.	PUNCT
admet-130	133	51	9	9	NUM
admet-130	134	1	(	(	PUNCT
admet-130	134	2	2003	2003	NUM
admet-130	134	3	)	)	PUNCT
admet-130	134	4	294	294	NUM
admet-130	134	5	-	-	SYM
admet-130	134	6	299	299	NUM
admet-130	134	7	.	.	PUNCT
admet-130	135	1	[	[	X
admet-130	135	2	3	3	NUM
admet-130	135	3	]	]	X
admet-130	135	4	k.a	k.a	PROPN
admet-130	135	5	.	.	PROPN
admet-130	135	6	head	head	PROPN
admet-130	135	7	,	,	PUNCT
admet-130	135	8	altern	altern	NOUN
admet-130	135	9	.	.	PUNCT
admet-130	136	1	med	med	PROPN
admet-130	136	2	.	.	PUNCT
admet-130	137	1	rev	rev	PROPN
admet-130	137	2	.	.	PROPN
admet-130	137	3	11	11	NUM
admet-130	137	4	(	(	PUNCT
admet-130	137	5	2006	2006	NUM
admet-130	137	6	)	)	PUNCT
admet-130	137	7	294	294	NUM
admet-130	137	8	-	-	SYM
admet-130	137	9	329	329	NUM
admet-130	137	10	.	.	PUNCT
admet-130	138	1	[	[	X
admet-130	138	2	4	4	X
admet-130	138	3	]	]	PUNCT
admet-130	138	4	t.	t.	PROPN
admet-130	138	5	varkonyi	varkonyi	PROPN
admet-130	138	6	,	,	PUNCT
admet-130	138	7	p.	p.	PROPN
admet-130	138	8	kempler	kempler	PROPN
admet-130	138	9	,	,	PUNCT
admet-130	138	10	diabetes	diabetes	NOUN
admet-130	138	11	obes	obe	NOUN
admet-130	138	12	.	.	PUNCT
admet-130	139	1	metab	metab	NOUN
admet-130	139	2	.	.	PUNCT
admet-130	140	1	10	10	NUM
admet-130	140	2	(	(	PUNCT
admet-130	140	3	2008	2008	NUM
admet-130	140	4	)	)	PUNCT
admet-130	140	5	99	99	NUM
admet-130	140	6	-	-	SYM
admet-130	140	7	108	108	NUM
admet-130	140	8	.	.	PUNCT
admet-130	141	1	[	[	X
admet-130	141	2	5	5	NUM
admet-130	141	3	]	]	PUNCT
admet-130	141	4	a.	a.	NOUN
admet-130	141	5	bierhaus	bierhaus	PROPN
admet-130	141	6	,	,	PUNCT
admet-130	141	7	t.	t.	PROPN
admet-130	141	8	fleming	fleming	PROPN
admet-130	141	9	,	,	PUNCT
admet-130	141	10	s.	s.	PROPN
admet-130	141	11	stoyano	stoyano	PROPN
admet-130	141	12	,	,	PUNCT
admet-130	141	13	a.	a.	NOUN
admet-130	141	14	leffler	leffler	NOUN
admet-130	141	15	,	,	PUNCT
admet-130	141	16	a.	a.	NOUN
admet-130	141	17	babes	babes	PROPN
admet-130	141	18	,	,	PUNCT
admet-130	141	19	c.	c.	PROPN
admet-130	141	20	neacsu	neacsu	PROPN
admet-130	141	21	,	,	PUNCT
admet-130	141	22	s.k	s.k	PROPN
admet-130	141	23	.	.	PROPN
admet-130	141	24	sauer	sauer	PROPN
admet-130	141	25	,	,	PUNCT
admet-130	141	26	m.	m.	NOUN
admet-130	141	27	eberhard	eberhard	NOUN
admet-130	141	28	,	,	PUNCT
admet-130	141	29	m.	m.	NOUN
admet-130	141	30	schnölze	schnölze	PROPN
admet-130	141	31	,	,	PUNCT
admet-130	141	32	f.	f.	PROPN
admet-130	141	33	lasischka	lasischka	PROPN
admet-130	141	34	,	,	PUNCT
admet-130	141	35	w.l	w.l	PROPN
admet-130	141	36	.	.	PROPN
admet-130	141	37	neuhuber	neuhuber	PROPN
admet-130	141	38	,	,	PUNCT
admet-130	141	39	t.i	t.i	PROPN
admet-130	141	40	.	.	PROPN
admet-130	141	41	kichko	kichko	PROPN
admet-130	141	42	,	,	PUNCT
admet-130	141	43	i.	i.	PROPN
admet-130	141	44	konrade	konrade	PROPN
admet-130	141	45	,	,	PUNCT
admet-130	141	46	r.	r.	PROPN
admet-130	141	47	elvert	elvert	PROPN
admet-130	141	48	,	,	PUNCT
admet-130	141	49	w.	w.	PROPN
admet-130	141	50	mier	mier	PROPN
admet-130	141	51	,	,	PUNCT
admet-130	141	52	v.	v.	PROPN
admet-130	141	53	pirags	pirags	PROPN
admet-130	141	54	,	,	PUNCT
admet-130	141	55	i.k	i.k	PROPN
admet-130	141	56	.	.	PROPN
admet-130	141	57	lukić	lukić	PROPN
admet-130	141	58	,	,	PUNCT
admet-130	141	59	m.	m.	NOUN
admet-130	141	60	morcos	morcos	PROPN
admet-130	141	61	,	,	PUNCT
admet-130	141	62	t.	t.	NOUN
admet-130	141	63	dehmer	dehmer	NOUN
admet-130	141	64	,	,	PUNCT
admet-130	141	65	n.	n.	NOUN
admet-130	141	66	rabbani	rabbani	PROPN
admet-130	141	67	,	,	PUNCT
admet-130	141	68	p.j	p.j	PROPN
admet-130	141	69	.	.	PROPN
admet-130	141	70	thornalley	thornalley	PROPN
admet-130	141	71	,	,	PUNCT
admet-130	141	72	d.	d.	PROPN
admet-130	141	73	edelstein	edelstein	PROPN
admet-130	141	74	,	,	PUNCT
admet-130	141	75	c.	c.	PROPN
admet-130	141	76	nau	nau	PROPN
admet-130	141	77	,	,	PUNCT
admet-130	141	78	j.	j.	PROPN
admet-130	141	79	forbes	forbes	PROPN
admet-130	141	80	,	,	PUNCT
admet-130	141	81	p.m.	p.m.	NOUN
admet-130	141	82	humpert	humpert	NOUN
admet-130	141	83	,	,	PUNCT
admet-130	141	84	m.	m.	NOUN
admet-130	141	85	schwaninger	schwaninger	NOUN
admet-130	141	86	,	,	PUNCT
admet-130	141	87	d.	d.	PROPN
admet-130	141	88	ziegler	ziegler	PROPN
admet-130	141	89	,	,	PUNCT
admet-130	141	90	d.m	d.m	PROPN
admet-130	141	91	.	.	PROPN
admet-130	141	92	stern	stern	PROPN
admet-130	141	93	,	,	PUNCT
admet-130	141	94	m.e	m.e	PROPN
admet-130	141	95	.	.	PROPN
admet-130	141	96	cooper	cooper	PROPN
admet-130	141	97	,	,	PUNCT
admet-130	141	98	u.	u.	PROPN
admet-130	141	99	haberkorn	haberkorn	PROPN
admet-130	141	100	,	,	PUNCT
admet-130	141	101	m.	m.	NOUN
admet-130	141	102	brownlee	brownlee	PROPN
admet-130	141	103	,	,	PUNCT
admet-130	141	104	p.w	p.w	PROPN
admet-130	141	105	.	.	PROPN
admet-130	141	106	reeh	reeh	PROPN
admet-130	141	107	,	,	PUNCT
admet-130	141	108	p.p	p.p	PROPN
admet-130	141	109	.	.	PROPN
admet-130	141	110	nawroth	nawroth	PROPN
admet-130	141	111	,	,	PUNCT
admet-130	141	112	nature	nature	NOUN
admet-130	141	113	med	me	VERB
admet-130	141	114	.	.	PUNCT
admet-130	141	115	18	18	NUM
admet-130	141	116	(	(	PUNCT
admet-130	141	117	2012	2012	NUM
admet-130	141	118	)	)	PUNCT
admet-130	141	119	926	926	NUM
admet-130	141	120	-	-	SYM
admet-130	141	121	933	933	NUM
admet-130	141	122	.	.	PUNCT
admet-130	142	1	[	[	X
admet-130	142	2	6	6	NUM
admet-130	142	3	]	]	PUNCT
admet-130	142	4	the	the	DET
admet-130	142	5	diabetes	diabetes	NOUN
admet-130	142	6	control	control	NOUN
admet-130	142	7	and	and	CCONJ
admet-130	142	8	complications	complication	NOUN
admet-130	142	9	trial	trial	NOUN
admet-130	142	10	research	research	NOUN
admet-130	142	11	group	group	NOUN
admet-130	142	12	.	.	PUNCT
admet-130	143	1	new	new	ADJ
admet-130	143	2	engl	engl	PROPN
admet-130	143	3	.	.	PUNCT
admet-130	144	1	j.	j.	PROPN
admet-130	144	2	med	med	PROPN
admet-130	144	3	.	.	PUNCT
admet-130	145	1	329	329	NUM
admet-130	145	2	(	(	PUNCT
admet-130	145	3	1993	1993	NUM
admet-130	145	4	)	)	PUNCT
admet-130	145	5	977986	977986	NUM
admet-130	145	6	.	.	PUNCT
admet-130	146	1	[	[	X
admet-130	146	2	7	7	X
admet-130	146	3	]	]	X
admet-130	146	4	the	the	DET
admet-130	146	5	effect	effect	NOUN
admet-130	146	6	of	of	ADP
admet-130	146	7	intensive	intensive	ADJ
admet-130	146	8	diabetes	diabetes	NOUN
admet-130	146	9	therapy	therapy	NOUN
admet-130	146	10	on	on	ADP
admet-130	146	11	the	the	DET
admet-130	146	12	development	development	NOUN
admet-130	146	13	and	and	CCONJ
admet-130	146	14	progression	progression	NOUN
admet-130	146	15	of	of	ADP
admet-130	146	16	neuropathy	neuropathy	ADJ
admet-130	146	17	.	.	PUNCT
admet-130	147	1	ann	ann	PROPN
admet-130	147	2	.	.	PUNCT
admet-130	148	1	int	int	PROPN
admet-130	148	2	.	.	PUNCT
admet-130	149	1	med	med	PROPN
admet-130	149	2	.	.	PUNCT
admet-130	150	1	122	122	NUM
admet-130	150	2	(	(	PUNCT
admet-130	150	3	1995	1995	NUM
admet-130	150	4	)	)	PUNCT
admet-130	150	5	561	561	NUM
admet-130	150	6	-	-	SYM
admet-130	150	7	568	568	NUM
admet-130	150	8	.	.	PUNCT
admet-130	151	1	[	[	X
admet-130	151	2	8	8	NUM
admet-130	151	3	]	]	X
admet-130	151	4	m.c	m.c	PROPN
admet-130	151	5	.	.	PROPN
admet-130	151	6	wong	wong	PROPN
admet-130	151	7	,	,	PUNCT
admet-130	151	8	j.w	j.w	PROPN
admet-130	151	9	.	.	PROPN
admet-130	151	10	chung	chung	PROPN
admet-130	151	11	,	,	PUNCT
admet-130	151	12	t.k	t.k	PROPN
admet-130	151	13	.	.	PROPN
admet-130	151	14	wong	wong	PROPN
admet-130	151	15	,	,	PUNCT
admet-130	151	16	bmj	bmj	PROPN
admet-130	151	17	(	(	PUNCT
admet-130	151	18	2007	2007	NUM
admet-130	151	19	)	)	PUNCT
admet-130	151	20	335:387	335:387	NOUN
admet-130	151	21	.	.	PUNCT
admet-130	152	1	[	[	X
admet-130	152	2	9	9	NUM
admet-130	152	3	]	]	SYM
admet-130	152	4	r.h	r.h	PROPN
admet-130	152	5	.	.	PROPN
admet-130	152	6	dworkin	dworkin	PROPN
admet-130	152	7	,	,	PUNCT
admet-130	152	8	d.c	d.c	PROPN
admet-130	152	9	.	.	PROPN
admet-130	152	10	turk	turk	PROPN
admet-130	152	11	,	,	PUNCT
admet-130	152	12	k.w	k.w	PROPN
admet-130	152	13	.	.	PROPN
admet-130	152	14	wyrwich	wyrwich	NOUN
admet-130	152	15	,	,	PUNCT
admet-130	152	16	d.	d.	PROPN
admet-130	152	17	beaton	beaton	PROPN
admet-130	152	18	,	,	PUNCT
admet-130	152	19	c.s	c.s	PROPN
admet-130	152	20	.	.	PROPN
admet-130	152	21	cleeland	cleeland	PROPN
admet-130	152	22	,	,	PUNCT
admet-130	152	23	j.t	j.t	PROPN
admet-130	152	24	.	.	PROPN
admet-130	152	25	farrar	farrar	PROPN
admet-130	152	26	,	,	PUNCT
admet-130	152	27	j.a	j.a	PROPN
admet-130	152	28	.	.	PROPN
admet-130	152	29	haythornthwaite	haythornthwaite	PROPN
admet-130	152	30	,	,	PUNCT
admet-130	152	31	m.p	m.p	PROPN
admet-130	152	32	.	.	PROPN
admet-130	152	33	jensen	jensen	PROPN
admet-130	152	34	,	,	PUNCT
admet-130	152	35	r.d	r.d	PROPN
admet-130	152	36	.	.	PROPN
admet-130	152	37	kerns	kerns	PROPN
admet-130	152	38	,	,	PUNCT
admet-130	152	39	d.n	d.n	PROPN
admet-130	152	40	.	.	PROPN
admet-130	152	41	ader	ader	PROPN
admet-130	152	42	,	,	PUNCT
admet-130	152	43	n.	n.	PROPN
admet-130	152	44	brandenburg	brandenburg	PROPN
admet-130	152	45	,	,	PUNCT
admet-130	152	46	l.b	l.b	PROPN
admet-130	152	47	.	.	PROPN
admet-130	152	48	burke	burke	PROPN
admet-130	152	49	,	,	PUNCT
admet-130	152	50	d.	d.	PROPN
admet-130	152	51	cella	cella	PROPN
admet-130	152	52	,	,	PUNCT
admet-130	152	53	j.	j.	PROPN
admet-130	152	54	chandler	chandler	PROPN
admet-130	152	55	,	,	PUNCT
admet-130	152	56	p.	p.	PROPN
admet-130	152	57	cowan	cowan	PROPN
admet-130	152	58	,	,	PUNCT
admet-130	152	59	r.	r.	PROPN
admet-130	152	60	dimitrova	dimitrova	PROPN
admet-130	152	61	,	,	PUNCT
admet-130	152	62	r.	r.	PROPN
admet-130	152	63	dionne	dionne	PROPN
admet-130	152	64	,	,	PUNCT
admet-130	152	65	s.	s.	PROPN
admet-130	152	66	hertz	hertz	PROPN
admet-130	152	67	,	,	PUNCT
admet-130	152	68	a.r	a.r	PROPN
admet-130	152	69	.	.	PROPN
admet-130	152	70	jadad	jadad	PROPN
admet-130	152	71	,	,	PUNCT
admet-130	152	72	n.p	n.p	PROPN
admet-130	152	73	.	.	PROPN
admet-130	152	74	katz	katz	PROPN
admet-130	152	75	,	,	PUNCT
admet-130	152	76	h.	h.	PROPN
admet-130	152	77	kehlet	kehlet	PROPN
admet-130	152	78	,	,	PUNCT
admet-130	152	79	l.d	l.d	PROPN
admet-130	152	80	.	.	PROPN
admet-130	152	81	kramer	kramer	PROPN
admet-130	152	82	,	,	PUNCT
admet-130	152	83	d.c	d.c	PROPN
admet-130	152	84	.	.	PUNCT
admet-130	152	85	manning	manning	PROPN
admet-130	152	86	,	,	PUNCT
admet-130	152	87	c.	c.	PROPN
admet-130	152	88	mccormick	mccormick	PROPN
admet-130	152	89	,	,	PUNCT
admet-130	152	90	m.p	m.p	PROPN
admet-130	152	91	.	.	PROPN
admet-130	152	92	mcdermott	mcdermott	PROPN
admet-130	152	93	,	,	PUNCT
admet-130	152	94	h.j	h.j	PROPN
admet-130	152	95	.	.	PROPN
admet-130	152	96	mcquay	mcquay	PROPN
admet-130	152	97	,	,	PUNCT
admet-130	152	98	s.	s.	PROPN
admet-130	152	99	patel	patel	PROPN
admet-130	152	100	,	,	PUNCT
admet-130	152	101	l.	l.	PROPN
admet-130	152	102	porter	porter	PROPN
admet-130	152	103	,	,	PUNCT
admet-130	152	104	s.	s.	PROPN
admet-130	152	105	quessy	quessy	PROPN
admet-130	152	106	,	,	PUNCT
admet-130	152	107	b.a	b.a	PROPN
admet-130	152	108	.	.	PROPN
admet-130	152	109	rappaport	rappaport	PROPN
admet-130	152	110	,	,	PUNCT
admet-130	152	111	c.	c.	PROPN
admet-130	152	112	rauschkolb	rauschkolb	PROPN
admet-130	152	113	,	,	PUNCT
admet-130	152	114	d.a	d.a	PROPN
admet-130	152	115	.	.	PROPN
admet-130	152	116	revicki	revicki	PROPN
admet-130	152	117	,	,	PUNCT
admet-130	152	118	m.	m.	NOUN
admet-130	152	119	rothman	rothman	PROPN
admet-130	152	120	,	,	PUNCT
admet-130	152	121	k.e	k.e	PROPN
admet-130	152	122	.	.	PROPN
admet-130	152	123	schmader	schmader	PROPN
admet-130	152	124	,	,	PUNCT
admet-130	152	125	b.r	b.r	PROPN
admet-130	152	126	.	.	PROPN
admet-130	152	127	stacey	stacey	PROPN
admet-130	152	128	,	,	PUNCT
admet-130	152	129	j.w	j.w	PROPN
admet-130	152	130	.	.	PROPN
admet-130	152	131	stauffer	stauffer	PROPN
admet-130	152	132	,	,	PUNCT
admet-130	152	133	t.	t.	PROPN
admet-130	152	134	von	von	PROPN
admet-130	152	135	stein	stein	PROPN
admet-130	152	136	,	,	PUNCT
admet-130	152	137	r.e	r.e	PROPN
admet-130	152	138	.	.	PROPN
admet-130	152	139	white	white	PROPN
admet-130	152	140	,	,	PUNCT
admet-130	152	141	j.	j.	PROPN
admet-130	152	142	witter	witter	PROPN
admet-130	152	143	,	,	PUNCT
admet-130	152	144	s.	s.	PROPN
admet-130	152	145	zavisi	zavisi	PROPN
admet-130	152	146	,	,	PUNCT
admet-130	152	147	pain	pain	NOUN
admet-130	152	148	9	9	NUM
admet-130	152	149	(	(	PUNCT
admet-130	152	150	2008	2008	NUM
admet-130	152	151	)	)	PUNCT
admet-130	152	152	105	105	NUM
admet-130	152	153	-	-	SYM
admet-130	152	154	121	121	NUM
admet-130	152	155	.	.	PUNCT
admet-130	153	1	[	[	X
admet-130	153	2	10	10	NUM
admet-130	153	3	]	]	X
admet-130	153	4	r.a	r.a	PROPN
admet-130	153	5	.	.	PROPN
admet-130	153	6	moore	moore	PROPN
admet-130	153	7	,	,	PUNCT
admet-130	153	8	s.	s.	PROPN
admet-130	153	9	straube	straube	PROPN
admet-130	153	10	,	,	PUNCT
admet-130	153	11	p.j	p.j	PROPN
admet-130	153	12	.	.	PROPN
admet-130	153	13	wiffen	wiffen	PROPN
admet-130	153	14	,	,	PUNCT
admet-130	153	15	s.	s.	PROPN
admet-130	153	16	derry	derry	PROPN
admet-130	153	17	,	,	PUNCT
admet-130	153	18	h.j	h.j	PROPN
admet-130	153	19	.	.	PROPN
admet-130	153	20	mcquay	mcquay	PROPN
admet-130	153	21	,	,	PUNCT
admet-130	153	22	the	the	DET
admet-130	153	23	cochrane	cochrane	NOUN
admet-130	153	24	database	database	NOUN
admet-130	153	25	of	of	ADP
admet-130	153	26	systematic	systematic	ADJ
admet-130	153	27	reviews	review	NOUN
admet-130	153	28	(	(	PUNCT
admet-130	153	29	2009	2009	NUM
admet-130	153	30	)	)	PUNCT
admet-130	153	31	cd007076	cd007076	NOUN
admet-130	153	32	.	.	PUNCT
admet-130	154	1	[	[	X
admet-130	154	2	11	11	NUM
admet-130	154	3	]	]	PUNCT
admet-130	154	4	s.	s.	PROPN
admet-130	154	5	quilici	quilici	PROPN
admet-130	154	6	,	,	PUNCT
admet-130	154	7	j.	j.	PROPN
admet-130	154	8	chancellor	chancellor	PROPN
admet-130	154	9	,	,	PUNCT
admet-130	154	10	m.	m.	PROPN
admet-130	154	11	lothgren	lothgren	PROPN
admet-130	154	12	,	,	PUNCT
admet-130	154	13	d.	d.	PROPN
admet-130	154	14	simon	simon	PROPN
admet-130	154	15	,	,	PUNCT
admet-130	154	16	g.	g.	PROPN
admet-130	154	17	said	say	VERB
admet-130	154	18	,	,	PUNCT
admet-130	154	19	t.k	t.k	PROPN
admet-130	154	20	.	.	PROPN
admet-130	154	21	le	le	PROPN
admet-130	154	22	,	,	PUNCT
admet-130	154	23	a.	a.	PROPN
admet-130	154	24	garcia	garcia	PROPN
admet-130	154	25	-	-	PUNCT
admet-130	154	26	cebrian	cebrian	PROPN
admet-130	154	27	,	,	PUNCT
admet-130	154	28	b.	b.	PROPN
admet-130	154	29	monz	monz	PROPN
admet-130	154	30	,	,	PUNCT
admet-130	154	31	bmc	bmc	NOUN
admet-130	154	32	neurology	neurology	NOUN
admet-130	154	33	9	9	NUM
admet-130	154	34	(	(	PUNCT
admet-130	154	35	2009	2009	NUM
admet-130	154	36	)	)	PUNCT
admet-130	154	37	6	6	NUM
admet-130	154	38	.	.	PUNCT
admet-130	155	1	[	[	X
admet-130	155	2	12	12	NUM
admet-130	155	3	]	]	PUNCT
admet-130	155	4	s.	s.	PROPN
admet-130	155	5	derry	derry	PROPN
admet-130	155	6	,	,	PUNCT
admet-130	155	7	a.	a.	PROPN
admet-130	155	8	sven	sven	PROPN
admet-130	155	9	-	-	PUNCT
admet-130	155	10	rice	rice	NOUN
admet-130	155	11	,	,	PUNCT
admet-130	155	12	p.	p.	NOUN
admet-130	155	13	cole	cole	PROPN
admet-130	155	14	,	,	PUNCT
admet-130	155	15	t.	t.	PROPN
admet-130	155	16	tan	tan	PROPN
admet-130	155	17	,	,	PUNCT
admet-130	155	18	r.a	r.a	PROPN
admet-130	155	19	.	.	PROPN
admet-130	155	20	moore	moore	PROPN
admet-130	155	21	,	,	PUNCT
admet-130	155	22	the	the	DET
admet-130	155	23	cochrane	cochrane	NOUN
admet-130	155	24	database	database	NOUN
admet-130	155	25	of	of	ADP
admet-130	155	26	systematic	systematic	ADJ
admet-130	155	27	reviews	review	NOUN
admet-130	155	28	2	2	NUM
admet-130	155	29	(	(	PUNCT
admet-130	155	30	2013	2013	NUM
admet-130	155	31	)	)	PUNCT
admet-130	155	32	cd007393	cd007393	PROPN
admet-130	155	33	.	.	PUNCT
admet-130	156	1	[	[	X
admet-130	156	2	13	13	NUM
admet-130	156	3	]	]	X
admet-130	156	4	g.l	g.l	PROPN
admet-130	156	5	.	.	PROPN
admet-130	156	6	page	page	PROPN
admet-130	156	7	,	,	PUNCT
admet-130	156	8	d.	d.	PROPN
admet-130	156	9	laight	laight	PROPN
admet-130	156	10	,	,	PUNCT
admet-130	156	11	m.h	m.h	PROPN
admet-130	156	12	.	.	PROPN
admet-130	156	13	cummings	cummings	PROPN
admet-130	156	14	,	,	PUNCT
admet-130	156	15	int	int	NOUN
admet-130	156	16	.	.	PUNCT
admet-130	157	1	j.	j.	PROPN
admet-130	157	2	clin	clin	PROPN
admet-130	157	3	.	.	PUNCT
admet-130	158	1	pract	pract	PROPN
admet-130	158	2	.	.	PUNCT
admet-130	159	1	65	65	NUM
admet-130	159	2	(	(	PUNCT
admet-130	159	3	2011	2011	NUM
admet-130	159	4	)	)	PUNCT
admet-130	159	5	684	684	NUM
admet-130	159	6	-	-	SYM
admet-130	159	7	690	690	NUM
admet-130	159	8	.	.	PUNCT
admet-130	160	1	[	[	X
admet-130	160	2	14	14	NUM
admet-130	160	3	]	]	X
admet-130	160	4	n.	n.	NOUN
admet-130	160	5	rabbani	rabbani	PROPN
admet-130	160	6	,	,	PUNCT
admet-130	160	7	p.j	p.j	PROPN
admet-130	160	8	.	.	PROPN
admet-130	160	9	thornalley	thornalley	PROPN
admet-130	160	10	,	,	PUNCT
admet-130	160	11	diabetes	diabetes	NOUN
admet-130	160	12	obes	obe	NOUN
admet-130	160	13	.	.	PUNCT
admet-130	161	1	metab	metab	NOUN
admet-130	161	2	.	.	PUNCT
admet-130	162	1	13	13	NUM
admet-130	162	2	(	(	PUNCT
admet-130	162	3	2011	2011	NUM
admet-130	162	4	)	)	PUNCT
admet-130	162	5	577	577	NUM
admet-130	162	6	-	-	SYM
admet-130	162	7	583	583	NUM
admet-130	162	8	.	.	PUNCT
admet-130	163	1	[	[	X
admet-130	163	2	15	15	NUM
admet-130	163	3	]	]	X
admet-130	163	4	m.	m.	NOUN
admet-130	163	5	gangolf	gangolf	PROPN
admet-130	163	6	,	,	PUNCT
admet-130	163	7	j.	j.	PROPN
admet-130	163	8	czerniecki	czerniecki	PROPN
admet-130	163	9	,	,	PUNCT
admet-130	163	10	m.	m.	NOUN
admet-130	163	11	radermecker	radermecker	NOUN
admet-130	163	12	,	,	PUNCT
admet-130	163	13	o.	o.	PROPN
admet-130	163	14	detry	detry	PROPN
admet-130	163	15	,	,	PUNCT
admet-130	163	16	m.	m.	NOUN
admet-130	163	17	nisolle	nisolle	PROPN
admet-130	163	18	,	,	PUNCT
admet-130	163	19	c.	c.	PROPN
admet-130	163	20	jouan	jouan	PROPN
admet-130	163	21	,	,	PUNCT
admet-130	163	22	d.	d.	PROPN
admet-130	163	23	martin	martin	PROPN
admet-130	163	24	,	,	PUNCT
admet-130	163	25	f.	f.	PROPN
admet-130	163	26	chantraine	chantraine	PROPN
admet-130	163	27	,	,	PUNCT
admet-130	163	28	b.	b.	PROPN
admet-130	163	29	lakaye	lakaye	PROPN
admet-130	163	30	,	,	PUNCT
admet-130	163	31	p.	p.	NOUN
admet-130	163	32	wins	win	NOUN
admet-130	163	33	,	,	PUNCT
admet-130	163	34	t.	t.	PROPN
admet-130	163	35	grisar	grisar	PROPN
admet-130	163	36	,	,	PUNCT
admet-130	163	37	l.	l.	PROPN
admet-130	163	38	bettendorff	bettendorff	PROPN
admet-130	163	39	,	,	PUNCT
admet-130	163	40	plos	plos	PROPN
admet-130	163	41	one	one	NUM
admet-130	163	42	5	5	NUM
admet-130	163	43	(	(	PUNCT
admet-130	163	44	2010	2010	NUM
admet-130	163	45	)	)	PUNCT
admet-130	164	1	e13616	e13616	NOUN
admet-130	164	2	.	.	PUNCT
admet-130	165	1	[	[	X
admet-130	165	2	16	16	NUM
admet-130	165	3	]	]	X
admet-130	165	4	p.j	p.j	PROPN
admet-130	165	5	.	.	PROPN
admet-130	165	6	thornalley	thornalley	PROPN
admet-130	165	7	,	,	PUNCT
admet-130	165	8	r.	r.	PROPN
admet-130	165	9	babaei	babaei	PROPN
admet-130	165	10	-	-	PUNCT
admet-130	165	11	jadidi	jadidi	PROPN
admet-130	165	12	,	,	PUNCT
admet-130	165	13	h.	h.	PROPN
admet-130	165	14	al	al	PROPN
admet-130	165	15	ali	ali	PROPN
admet-130	165	16	,	,	PUNCT
admet-130	165	17	n.	n.	PROPN
admet-130	165	18	rabbani	rabbani	PROPN
admet-130	165	19	,	,	PUNCT
admet-130	165	20	a.	a.	NOUN
admet-130	165	21	antonysunil	antonysunil	PROPN
admet-130	165	22	,	,	PUNCT
admet-130	165	23	j.	j.	PROPN
admet-130	165	24	larkin	larkin	PROPN
admet-130	165	25	,	,	PUNCT
admet-130	165	26	a.	a.	PROPN
admet-130	165	27	ahmed	ahmed	PROPN
admet-130	165	28	,	,	PUNCT
admet-130	165	29	g.	g.	PROPN
admet-130	165	30	rayman	rayman	PROPN
admet-130	165	31	,	,	PUNCT
admet-130	165	32	c.w	c.w	PROPN
admet-130	165	33	.	.	PROPN
admet-130	165	34	bodmer	bodmer	PROPN
admet-130	165	35	,	,	PUNCT
admet-130	165	36	diabetologia	diabetologia	NOUN
admet-130	165	37	50	50	NUM
admet-130	165	38	(	(	PUNCT
admet-130	165	39	2007	2007	NUM
admet-130	165	40	)	)	PUNCT
admet-130	165	41	2164	2164	NUM
admet-130	165	42	-	-	SYM
admet-130	165	43	2170	2170	NUM
admet-130	165	44	.	.	PUNCT
admet-130	166	1	[	[	X
admet-130	166	2	17	17	NUM
admet-130	166	3	]	]	PUNCT
admet-130	166	4	j.	j.	PROPN
admet-130	166	5	r.	r.	PROPN
admet-130	166	6	larkin	larkin	PROPN
admet-130	166	7	,	,	PUNCT
admet-130	166	8	f.	f.	PROPN
admet-130	166	9	zhang	zhang	PROPN
admet-130	166	10	,	,	PUNCT
admet-130	166	11	l.	l.	PROPN
admet-130	166	12	godfrey	godfrey	PROPN
admet-130	166	13	,	,	PUNCT
admet-130	166	14	g.	g.	PROPN
admet-130	166	15	molostvov	molostvov	PROPN
admet-130	166	16	,	,	PUNCT
admet-130	166	17	d.	d.	PROPN
admet-130	166	18	zehnder	zehnder	PROPN
admet-130	166	19	,	,	PUNCT
admet-130	166	20	n.	n.	PROPN
admet-130	166	21	rabbani	rabbani	PROPN
admet-130	166	22	,	,	PUNCT
admet-130	166	23	p.	p.	PROPN
admet-130	166	24	j.	j.	PROPN
admet-130	166	25	thornalley	thornalley	PROPN
admet-130	166	26	,	,	PUNCT
admet-130	166	27	plos	plos	PROPN
admet-130	166	28	one	one	NUM
admet-130	166	29	7	7	NUM
admet-130	166	30	(	(	PUNCT
admet-130	166	31	2012	2012	NUM
admet-130	166	32	)	)	PUNCT
admet-130	166	33	e53175	e53175	PROPN
admet-130	166	34	.	.	PUNCT
admet-130	167	1	[	[	X
admet-130	167	2	18	18	NUM
admet-130	167	3	]	]	X
admet-130	167	4	r.	r.	PROPN
admet-130	167	5	babaei	babaei	PROPN
admet-130	167	6	-	-	PUNCT
admet-130	167	7	jadidi	jadidi	VERB
admet-130	167	8	,	,	PUNCT
admet-130	167	9	n.	n.	PROPN
admet-130	167	10	karachalias	karachalias	PROPN
admet-130	167	11	,	,	PUNCT
admet-130	167	12	n.	n.	PROPN
admet-130	167	13	ahmed	ahmed	PROPN
admet-130	167	14	,	,	PUNCT
admet-130	167	15	s.	s.	PROPN
admet-130	167	16	battah	battah	PROPN
admet-130	167	17	,	,	PUNCT
admet-130	167	18	p.j	p.j	PROPN
admet-130	167	19	.	.	PROPN
admet-130	167	20	thornalley	thornalley	PROPN
admet-130	167	21	,	,	PUNCT
admet-130	167	22	diabetes	diabete	VERB
admet-130	167	23	52	52	NUM
admet-130	167	24	(	(	PUNCT
admet-130	167	25	2003	2003	NUM
admet-130	167	26	)	)	PUNCT
admet-130	167	27	2110	2110	NUM
admet-130	167	28	-	-	SYM
admet-130	167	29	2120	2120	NUM
admet-130	167	30	.	.	PUNCT
admet-130	168	1	[	[	X
admet-130	168	2	19	19	NUM
admet-130	168	3	]	]	X
admet-130	168	4	r.	r.	PROPN
admet-130	168	5	masson	masson	PROPN
admet-130	168	6	,	,	PUNCT
admet-130	168	7	c.	c.	PROPN
admet-130	168	8	quincy	quincy	PROPN
admet-130	168	9	,	,	PUNCT
admet-130	168	10	p.	p.	PROPN
admet-130	168	11	girard	girard	PROPN
admet-130	168	12	,	,	PUNCT
admet-130	168	13	r.	r.	PROPN
admet-130	168	14	later	later	ADV
admet-130	168	15	,	,	PUNCT
admet-130	168	16	b.	b.	PROPN
admet-130	168	17	bochu	bochu	PROPN
admet-130	168	18	,	,	PUNCT
admet-130	168	19	m.f	m.f	PROPN
admet-130	168	20	.	.	PROPN
admet-130	168	21	cotte	cotte	PROPN
admet-130	168	22	,	,	PUNCT
admet-130	168	23	lyon	lyon	PROPN
admet-130	168	24	med	me	VERB
admet-130	168	25	.	.	PUNCT
admet-130	169	1	216	216	NUM
admet-130	169	2	(	(	PUNCT
admet-130	169	3	1966	1966	NUM
admet-130	169	4	)	)	PUNCT
admet-130	169	5	685	685	NUM
admet-130	169	6	-	-	SYM
admet-130	169	7	704	704	NUM
admet-130	169	8	.	.	PUNCT
admet-130	170	1	[	[	X
admet-130	170	2	20	20	NUM
admet-130	170	3	]	]	PUNCT
admet-130	170	4	r.	r.	PROPN
admet-130	170	5	hilbig	hilbig	PROPN
admet-130	170	6	h.	h.	PROPN
admet-130	170	7	rahmann	rahmann	PROPN
admet-130	170	8	,	,	PUNCT
admet-130	170	9	arzneimittelforschung	arzneimittelforschung	VERB
admet-130	170	10	48	48	NUM
admet-130	170	11	(	(	PUNCT
admet-130	170	12	1998	1998	NUM
admet-130	170	13	)	)	PUNCT
admet-130	170	14	461	461	NUM
admet-130	170	15	-	-	SYM
admet-130	170	16	468	468	NUM
admet-130	170	17	.	.	PUNCT
admet-130	171	1	varadi	varadi	PROPN
admet-130	171	2	et.al	et.al	PROPN
admet-130	171	3	.	.	PUNCT
admet-130	172	1	admet	admet	PROPN
admet-130	172	2	&	&	CCONJ
admet-130	172	3	dmpk	dmpk	PROPN
admet-130	172	4	2(4	2(4	NUM
admet-130	172	5	)	)	PUNCT
admet-130	172	6	(	(	PUNCT
admet-130	172	7	2014	2014	NUM
admet-130	172	8	)	)	PUNCT
admet-130	172	9	272	272	NUM
admet-130	172	10	-	-	SYM
admet-130	172	11	281	281	NUM
admet-130	172	12	280	280	NUM
admet-130	172	13	[	[	X
admet-130	172	14	21	21	NUM
admet-130	172	15	]	]	PUNCT
admet-130	172	16	h.	h.	PROPN
admet-130	172	17	stracke	stracke	PROPN
admet-130	172	18	,	,	PUNCT
admet-130	172	19	h.p	h.p	PROPN
admet-130	172	20	.	.	PROPN
admet-130	172	21	hammes	hammes	PROPN
admet-130	172	22	,	,	PUNCT
admet-130	172	23	d.	d.	PROPN
admet-130	172	24	werkmann	werkmann	PROPN
admet-130	172	25	,	,	PUNCT
admet-130	172	26	k.	k.	PROPN
admet-130	172	27	mavrakis	mavrakis	PROPN
admet-130	172	28	,	,	PUNCT
admet-130	172	29	i.	i.	PROPN
admet-130	172	30	bitsch	bitsch	PROPN
admet-130	172	31	,	,	PUNCT
admet-130	172	32	m.	m.	PROPN
admet-130	172	33	netzel	netzel	PROPN
admet-130	172	34	,	,	PUNCT
admet-130	172	35	j.	j.	PROPN
admet-130	172	36	geyer	geyer	PROPN
admet-130	172	37	,	,	PUNCT
admet-130	172	38	w.	w.	PROPN
admet-130	172	39	köpcke	köpcke	PROPN
admet-130	172	40	,	,	PUNCT
admet-130	172	41	c.	c.	PROPN
admet-130	172	42	sauerland	sauerland	PROPN
admet-130	172	43	,	,	PUNCT
admet-130	172	44	r.g	r.g	PROPN
admet-130	172	45	.	.	PROPN
admet-130	172	46	bretzel	bretzel	PROPN
admet-130	172	47	,	,	PUNCT
admet-130	172	48	k.f	k.f	PROPN
admet-130	172	49	.	.	PROPN
admet-130	172	50	federlin	federlin	PROPN
admet-130	172	51	,	,	PUNCT
admet-130	172	52	exp	exp	NOUN
admet-130	172	53	.	.	PUNCT
admet-130	173	1	clin	clin	PROPN
admet-130	173	2	.	.	PUNCT
admet-130	173	3	endocrinol	endocrinol	NOUN
admet-130	173	4	.	.	PUNCT
admet-130	174	1	diabetes	diabetes	NOUN
admet-130	174	2	109	109	NUM
admet-130	174	3	(	(	PUNCT
admet-130	174	4	2001	2001	NUM
admet-130	174	5	)	)	PUNCT
admet-130	174	6	330	330	NUM
admet-130	174	7	-	-	SYM
admet-130	174	8	336	336	NUM
admet-130	174	9	.	.	PUNCT
admet-130	175	1	[	[	X
admet-130	175	2	22	22	NUM
admet-130	175	3	]	]	PUNCT
admet-130	175	4	m.	m.	NOUN
admet-130	175	5	l.	l.	PROPN
admet-130	175	6	volvert	volvert	PROPN
admet-130	175	7	,	,	PUNCT
admet-130	175	8	s.	s.	PROPN
admet-130	175	9	seyen	seyen	PROPN
admet-130	175	10	,	,	PUNCT
admet-130	175	11	m.	m.	NOUN
admet-130	175	12	piette	piette	PROPN
admet-130	175	13	,	,	PUNCT
admet-130	175	14	b.	b.	PROPN
admet-130	175	15	evrard	evrard	PROPN
admet-130	175	16	,	,	PUNCT
admet-130	175	17	m.	m.	NOUN
admet-130	175	18	gangolf	gangolf	PROPN
admet-130	175	19	,	,	PUNCT
admet-130	175	20	j.	j.	PROPN
admet-130	175	21	c.	c.	PROPN
admet-130	175	22	plumier	plumier	PROPN
admet-130	175	23	,	,	PUNCT
admet-130	175	24	l.	l.	PROPN
admet-130	175	25	bettendorf	bettendorf	PROPN
admet-130	175	26	,	,	PUNCT
admet-130	175	27	bmc	bmc	PROPN
admet-130	175	28	pharmacol	pharmacol	NOUN
admet-130	175	29	.	.	PROPN
admet-130	175	30	8	8	NUM
admet-130	175	31	(	(	PUNCT
admet-130	175	32	2008	2008	NUM
admet-130	175	33	)	)	PUNCT
admet-130	175	34	10	10	NUM
admet-130	175	35	.	.	PUNCT
admet-130	176	1	[	[	X
admet-130	176	2	23	23	NUM
admet-130	176	3	]	]	X
admet-130	176	4	e.	e.	PROPN
admet-130	176	5	beltramo	beltramo	PROPN
admet-130	176	6	,	,	PUNCT
admet-130	176	7	e.	e.	PROPN
admet-130	176	8	berrone	berrone	PROPN
admet-130	176	9	,	,	PUNCT
admet-130	176	10	s.	s.	PROPN
admet-130	176	11	tarallo	tarallo	PROPN
admet-130	176	12	,	,	PUNCT
admet-130	176	13	m.	m.	NOUN
admet-130	176	14	porta	porta	PROPN
admet-130	176	15	,	,	PUNCT
admet-130	176	16	acta	acta	PROPN
admet-130	176	17	diabetol	diabetol	ADJ
admet-130	176	18	.	.	PUNCT
admet-130	177	1	45	45	NUM
admet-130	177	2	(	(	PUNCT
admet-130	177	3	2008	2008	NUM
admet-130	177	4	)	)	PUNCT
admet-130	177	5	,	,	PUNCT
admet-130	177	6	131	131	NUM
admet-130	177	7	-	-	SYM
admet-130	177	8	141	141	NUM
admet-130	177	9	.	.	PUNCT
admet-130	178	1	[	[	X
admet-130	178	2	24	24	NUM
admet-130	178	3	]	]	X
admet-130	178	4	h.	h.	PROPN
admet-130	178	5	woelk	woelk	PROPN
admet-130	178	6	,	,	PUNCT
admet-130	178	7	s.	s.	PROPN
admet-130	178	8	lehrl	lehrl	PROPN
admet-130	178	9	,	,	PUNCT
admet-130	178	10	r.	r.	PROPN
admet-130	178	11	bitsch	bitsch	PROPN
admet-130	178	12	,	,	PUNCT
admet-130	178	13	w.	w.	PROPN
admet-130	178	14	kopcke	kopcke	PROPN
admet-130	178	15	,	,	PUNCT
admet-130	178	16	alcohol	alcohol	NOUN
admet-130	178	17	33	33	NUM
admet-130	178	18	(	(	PUNCT
admet-130	178	19	1998	1998	NUM
admet-130	178	20	)	)	PUNCT
admet-130	178	21	631	631	NUM
admet-130	178	22	-	-	PUNCT
admet-130	178	23	638	638	NUM
admet-130	178	24	.	.	PUNCT
admet-130	179	1	[	[	X
admet-130	179	2	25	25	NUM
admet-130	179	3	]	]	X
admet-130	179	4	e.i	e.i	PROPN
admet-130	179	5	.	.	PROPN
admet-130	179	6	anisimova	anisimova	PROPN
admet-130	179	7	,	,	PUNCT
admet-130	179	8	a.b	a.b	PROPN
admet-130	179	9	.	.	PROPN
admet-130	179	10	danilov	danilov	PROPN
admet-130	179	11	,	,	PUNCT
admet-130	179	12	zh	zh	PROPN
admet-130	179	13	.	.	PUNCT
admet-130	179	14	nevrol	nevrol	PROPN
admet-130	179	15	.	.	PUNCT
admet-130	180	1	psikhiatr	psikhiatr	ADV
admet-130	180	2	.	.	PUNCT
admet-130	181	1	i	i	PRON
admet-130	181	2	m.	m.	NOUN
admet-130	181	3	s.	s.	PROPN
admet-130	181	4	s	s	PART
admet-130	181	5	korsakova	korsakova	NOUN
admet-130	181	6	101	101	NUM
admet-130	181	7	(	(	PUNCT
admet-130	181	8	2001	2001	NUM
admet-130	181	9	)	)	PUNCT
admet-130	181	10	32	32	NUM
admet-130	181	11	-	-	SYM
admet-130	181	12	36	36	NUM
admet-130	181	13	.	.	PUNCT
admet-130	182	1	[	[	X
admet-130	182	2	26	26	NUM
admet-130	182	3	]	]	X
admet-130	182	4	e.	e.	PROPN
admet-130	182	5	haupt	haupt	PROPN
admet-130	182	6	,	,	PUNCT
admet-130	182	7	h.	h.	PROPN
admet-130	182	8	ledermann	ledermann	PROPN
admet-130	182	9	,	,	PUNCT
admet-130	182	10	w.	w.	PROPN
admet-130	182	11	kopcke	kopcke	PROPN
admet-130	182	12	,	,	PUNCT
admet-130	182	13	int	int	PROPN
admet-130	182	14	.	.	PUNCT
admet-130	183	1	j.	j.	PROPN
admet-130	183	2	clin	clin	PROPN
admet-130	183	3	.	.	PUNCT
admet-130	184	1	pharmacol	pharmacol	PROPN
admet-130	184	2	.	.	PUNCT
admet-130	185	1	ther	ther	PROPN
admet-130	185	2	.	.	PUNCT
admet-130	186	1	43	43	NUM
admet-130	186	2	(	(	PUNCT
admet-130	186	3	2005	2005	NUM
admet-130	186	4	)	)	PUNCT
admet-130	186	5	71	71	NUM
admet-130	186	6	-	-	SYM
admet-130	186	7	77	77	NUM
admet-130	186	8	.	.	PUNCT
admet-130	187	1	[	[	X
admet-130	187	2	27	27	NUM
admet-130	187	3	]	]	X
admet-130	187	4	g.	g.	PROPN
admet-130	187	5	winkler	winkler	PROPN
admet-130	187	6	,	,	PUNCT
admet-130	187	7	b.	b.	PROPN
admet-130	187	8	pal	pal	PROPN
admet-130	187	9	,	,	PUNCT
admet-130	187	10	e.	e.	PROPN
admet-130	187	11	nagybeganyi	nagybeganyi	PROPN
admet-130	187	12	,	,	PUNCT
admet-130	187	13	i	i	PROPN
admet-130	187	14	ory	ory	NOUN
admet-130	187	15	,	,	PUNCT
admet-130	187	16	m.	m.	NOUN
admet-130	187	17	porochnavec	porochnavec	PROPN
admet-130	187	18	,	,	PUNCT
admet-130	187	19	p.	p.	PROPN
admet-130	187	20	kempler	kempler	PROPN
admet-130	187	21	,	,	PUNCT
admet-130	187	22	arzneimittelforschung	arzneimittelforschung	VERB
admet-130	187	23	49	49	NUM
admet-130	187	24	(	(	PUNCT
admet-130	187	25	1999	1999	NUM
admet-130	187	26	)	)	PUNCT
admet-130	187	27	220	220	NUM
admet-130	187	28	-	-	SYM
admet-130	187	29	224	224	NUM
admet-130	187	30	.	.	PUNCT
admet-130	188	1	[	[	X
admet-130	188	2	28	28	NUM
admet-130	188	3	]	]	X
admet-130	188	4	h.	h.	PROPN
admet-130	188	5	stracke	stracke	PROPN
admet-130	188	6	,	,	PUNCT
admet-130	188	7	w.	w.	PROPN
admet-130	188	8	gauss	gauss	PROPN
admet-130	188	9	,	,	PUNCT
admet-130	188	10	u.	u.	PROPN
admet-130	188	11	achenbach	achenbach	PROPN
admet-130	188	12	,	,	PUNCT
admet-130	188	13	k.	k.	PROPN
admet-130	188	14	federlin	federlin	PROPN
admet-130	188	15	,	,	PUNCT
admet-130	188	16	r.g	r.g	PROPN
admet-130	188	17	.	.	PROPN
admet-130	188	18	bretzel	bretzel	NOUN
admet-130	188	19	,	,	PUNCT
admet-130	188	20	exp	exp	NOUN
admet-130	188	21	.	.	PUNCT
admet-130	189	1	clin	clin	PROPN
admet-130	189	2	.	.	PUNCT
admet-130	189	3	endocrinol	endocrinol	NOUN
admet-130	189	4	.	.	PUNCT
admet-130	190	1	diabetes	diabetes	NOUN
admet-130	190	2	116	116	NUM
admet-130	190	3	(	(	PUNCT
admet-130	190	4	2008	2008	NUM
admet-130	190	5	)	)	PUNCT
admet-130	190	6	600	600	NUM
admet-130	190	7	-	-	SYM
admet-130	190	8	605	605	NUM
admet-130	190	9	.	.	PUNCT
admet-130	191	1	[	[	X
admet-130	191	2	29	29	NUM
admet-130	191	3	]	]	PUNCT
admet-130	191	4	x.	x.	NOUN
admet-130	191	5	du	du	PROPN
admet-130	191	6	,	,	PUNCT
admet-130	191	7	d.	d.	PROPN
admet-130	191	8	edelstein	edelstein	PROPN
admet-130	191	9	,	,	PUNCT
admet-130	191	10	m.	m.	PROPN
admet-130	191	11	brownlee	brownlee	PROPN
admet-130	191	12	,	,	PUNCT
admet-130	191	13	diabetologia	diabetologia	NOUN
admet-130	191	14	51	51	NUM
admet-130	191	15	(	(	PUNCT
admet-130	191	16	2008	2008	NUM
admet-130	191	17	)	)	PUNCT
admet-130	191	18	1930	1930	NUM
admet-130	191	19	-	-	SYM
admet-130	191	20	1932	1932	NUM
admet-130	191	21	.	.	PUNCT
admet-130	192	1	[	[	X
admet-130	192	2	30	30	NUM
admet-130	192	3	]	]	X
admet-130	192	4	c.d	c.d	PROPN
admet-130	192	5	.	.	PROPN
admet-130	192	6	ang	ang	PROPN
admet-130	192	7	,	,	PUNCT
admet-130	192	8	m.j	m.j	PROPN
admet-130	192	9	.	.	PROPN
admet-130	192	10	alviar	alviar	PROPN
admet-130	192	11	,	,	PUNCT
admet-130	192	12	a.l	a.l	PROPN
admet-130	192	13	.	.	PROPN
admet-130	192	14	dans	dans	PROPN
admet-130	192	15	,	,	PUNCT
admet-130	192	16	g.g	g.g	PROPN
admet-130	192	17	.	.	PROPN
admet-130	192	18	bautista	bautista	PROPN
admet-130	192	19	-	-	PUNCT
admet-130	192	20	velez	velez	PROPN
admet-130	192	21	,	,	PUNCT
admet-130	192	22	v.v	v.v	PROPN
admet-130	192	23	.	.	PROPN
admet-130	192	24	villaruz	villaruz	PROPN
admet-130	192	25	-	-	PUNCT
admet-130	192	26	sulit	sulit	PROPN
admet-130	192	27	,	,	PUNCT
admet-130	192	28	j.j	j.j	PROPN
admet-130	192	29	.	.	PROPN
admet-130	192	30	tan	tan	PROPN
admet-130	192	31	,	,	PUNCT
admet-130	192	32	h.u	h.u	PROPN
admet-130	192	33	.	.	PUNCT
admet-130	192	34	co	co	PROPN
admet-130	192	35	,	,	PUNCT
admet-130	192	36	m.r	m.r	PROPN
admet-130	192	37	.	.	PROPN
admet-130	192	38	bautista	bautista	PROPN
admet-130	192	39	,	,	PUNCT
admet-130	192	40	cochrane	cochrane	PROPN
admet-130	192	41	database	database	NOUN
admet-130	192	42	systematic	systematic	ADJ
admet-130	192	43	reviews	review	NOUN
admet-130	192	44	16	16	NUM
admet-130	192	45	(	(	PUNCT
admet-130	192	46	2008	2008	NUM
admet-130	192	47	)	)	PUNCT
admet-130	192	48	cd004573	cd004573	NOUN
admet-130	192	49	.	.	PUNCT
admet-130	193	1	[	[	X
admet-130	193	2	31	31	NUM
admet-130	193	3	]	]	X
admet-130	193	4	n.	n.	NOUN
admet-130	193	5	karachalias	karachalias	PROPN
admet-130	193	6	,	,	PUNCT
admet-130	193	7	r.	r.	PROPN
admet-130	193	8	babaei	babaei	PROPN
admet-130	193	9	-	-	PUNCT
admet-130	193	10	jadidi	jadidi	VERB
admet-130	193	11	,	,	PUNCT
admet-130	193	12	n.	n.	PROPN
admet-130	193	13	ahmed	ahmed	PROPN
admet-130	193	14	,	,	PUNCT
admet-130	193	15	p.j	p.j	PROPN
admet-130	193	16	.	.	PROPN
admet-130	193	17	thornalley	thornalley	PROPN
admet-130	193	18	,	,	PUNCT
admet-130	193	19	biochem	biochem	PROPN
admet-130	193	20	.	.	PUNCT
admet-130	194	1	soc	soc	PROPN
admet-130	194	2	.	.	PUNCT
admet-130	195	1	trans	trans	PROPN
admet-130	195	2	.	.	PROPN
admet-130	196	1	31	31	NUM
admet-130	196	2	(	(	PUNCT
admet-130	196	3	2003	2003	NUM
admet-130	196	4	)	)	PUNCT
admet-130	196	5	14231425	14231425	NUM
admet-130	196	6	.	.	PUNCT
admet-130	197	1	[	[	X
admet-130	197	2	32	32	NUM
admet-130	197	3	]	]	PUNCT
admet-130	197	4	r.	r.	PROPN
admet-130	197	5	babaei	babaei	PROPN
admet-130	197	6	-	-	PUNCT
admet-130	197	7	jadidi	jadidi	VERB
admet-130	197	8	,	,	PUNCT
admet-130	197	9	n.	n.	PROPN
admet-130	197	10	karachalias	karachalias	PROPN
admet-130	197	11	,	,	PUNCT
admet-130	197	12	c.	c.	PROPN
admet-130	197	13	kupich	kupich	PROPN
admet-130	197	14	,	,	PUNCT
admet-130	197	15	n.	n.	PROPN
admet-130	197	16	ahmed	ahmed	PROPN
admet-130	197	17	,	,	PUNCT
admet-130	197	18	p.j	p.j	PROPN
admet-130	197	19	.	.	PROPN
admet-130	197	20	thornalley	thornalley	PROPN
admet-130	197	21	,	,	PUNCT
admet-130	197	22	diabetologia	diabetologia	NOUN
admet-130	197	23	47	47	NUM
admet-130	197	24	(	(	PUNCT
admet-130	197	25	2004	2004	NUM
admet-130	197	26	)	)	PUNCT
admet-130	197	27	22352246	22352246	NUM
admet-130	197	28	.	.	PUNCT
admet-130	198	1	[	[	X
admet-130	198	2	33	33	NUM
admet-130	198	3	]	]	X
admet-130	198	4	n.	n.	NOUN
admet-130	198	5	karachalias	karachalias	PROPN
admet-130	198	6	,	,	PUNCT
admet-130	198	7	r.	r.	PROPN
admet-130	198	8	babaei	babaei	PROPN
admet-130	198	9	-	-	PUNCT
admet-130	198	10	jadidi	jadidi	VERB
admet-130	198	11	,	,	PUNCT
admet-130	198	12	c.	c.	PROPN
admet-130	198	13	kupich	kupich	PROPN
admet-130	198	14	,	,	PUNCT
admet-130	198	15	n.	n.	PROPN
admet-130	198	16	ahmed	ahmed	PROPN
admet-130	198	17	,	,	PUNCT
admet-130	198	18	p.j	p.j	PROPN
admet-130	198	19	.	.	PROPN
admet-130	198	20	thornalley	thornalley	PROPN
admet-130	198	21	,	,	PUNCT
admet-130	198	22	ann	ann	PROPN
admet-130	198	23	.	.	PUNCT
admet-130	198	24	n.	n.	PROPN
admet-130	198	25	y.	y.	PROPN
admet-130	198	26	acad	acad	PROPN
admet-130	198	27	.	.	PUNCT
admet-130	199	1	sci	sci	PROPN
admet-130	199	2	.	.	PROPN
admet-130	199	3	1043	1043	NUM
admet-130	199	4	(	(	PUNCT
admet-130	199	5	2005	2005	NUM
admet-130	199	6	)	)	PUNCT
admet-130	199	7	777	777	NUM
admet-130	199	8	-	-	SYM
admet-130	199	9	783	783	NUM
admet-130	199	10	.	.	PUNCT
admet-130	200	1	[	[	X
admet-130	200	2	34	34	NUM
admet-130	200	3	]	]	X
admet-130	200	4	n.	n.	NOUN
admet-130	200	5	karachalias	karachalias	PROPN
admet-130	200	6	,	,	PUNCT
admet-130	200	7	r.	r.	PROPN
admet-130	200	8	babaei	babaei	PROPN
admet-130	200	9	-	-	PUNCT
admet-130	200	10	jadidi	jadidi	VERB
admet-130	200	11	,	,	PUNCT
admet-130	200	12	n.	n.	NOUN
admet-130	200	13	rabbani	rabbani	PROPN
admet-130	200	14	,	,	PUNCT
admet-130	200	15	p.j	p.j	PROPN
admet-130	200	16	.	.	PROPN
admet-130	200	17	thornalley	thornalley	PROPN
admet-130	200	18	,	,	PUNCT
admet-130	200	19	diabetologia	diabetologia	NOUN
admet-130	200	20	53	53	NUM
admet-130	200	21	(	(	PUNCT
admet-130	200	22	2010	2010	NUM
admet-130	200	23	)	)	PUNCT
admet-130	200	24	1506	1506	NUM
admet-130	200	25	-	-	SYM
admet-130	200	26	1516	1516	NUM
admet-130	200	27	.	.	PUNCT
admet-130	201	1	[	[	X
admet-130	201	2	35	35	NUM
admet-130	201	3	]	]	X
admet-130	201	4	a.f	a.f	PROPN
admet-130	201	5	.	.	PUNCT
admet-130	201	6	ceylan	ceylan	PROPN
admet-130	201	7	-	-	PUNCT
admet-130	201	8	isik	isik	PROPN
admet-130	201	9	,	,	PUNCT
admet-130	201	10	s.	s.	PROPN
admet-130	201	11	wu	wu	PROPN
admet-130	201	12	,	,	PUNCT
admet-130	201	13	q.	q.	PROPN
admet-130	201	14	li	li	PROPN
admet-130	201	15	,	,	PUNCT
admet-130	201	16	s.	s.	PROPN
admet-130	201	17	y.	y.	PROPN
admet-130	201	18	li	li	PROPN
admet-130	201	19	,	,	PUNCT
admet-130	201	20	j.	j.	PROPN
admet-130	201	21	ren	ren	PROPN
admet-130	201	22	,	,	PUNCT
admet-130	201	23	j.	j.	PROPN
admet-130	201	24	appl	appl	PROPN
admet-130	201	25	.	.	PUNCT
admet-130	201	26	physiol	physiol	PROPN
admet-130	201	27	.	.	PUNCT
admet-130	202	1	100	100	NUM
admet-130	202	2	(	(	PUNCT
admet-130	202	3	2006	2006	NUM
admet-130	202	4	)	)	PUNCT
admet-130	202	5	150	150	NUM
admet-130	202	6	-	-	SYM
admet-130	202	7	156	156	NUM
admet-130	202	8	.	.	PUNCT
admet-130	203	1	[	[	X
admet-130	203	2	36	36	NUM
admet-130	203	3	]	]	X
admet-130	203	4	y.	y.	PROPN
admet-130	203	5	kohda	kohda	PROPN
admet-130	203	6	,	,	PUNCT
admet-130	203	7	h.	h.	PROPN
admet-130	203	8	shirakawa	shirakawa	PROPN
admet-130	203	9	,	,	PUNCT
admet-130	203	10	k.	k.	PROPN
admet-130	203	11	yamane	yamane	PROPN
admet-130	203	12	,	,	PUNCT
admet-130	203	13	k.	k.	PROPN
admet-130	203	14	otsuka	otsuka	PROPN
admet-130	203	15	,	,	PUNCT
admet-130	203	16	t.	t.	PROPN
admet-130	203	17	kono	kono	PROPN
admet-130	203	18	,	,	PUNCT
admet-130	203	19	f.	f.	PROPN
admet-130	203	20	terasaki	terasaki	PROPN
admet-130	203	21	,	,	PUNCT
admet-130	203	22	t.	t.	PROPN
admet-130	203	23	tanaka	tanaka	PROPN
admet-130	203	24	,	,	PUNCT
admet-130	203	25	j.	j.	PROPN
admet-130	203	26	toxicol	toxicol	PROPN
admet-130	203	27	.	.	PUNCT
admet-130	204	1	sci	sci	PROPN
admet-130	204	2	.	.	PROPN
admet-130	205	1	33	33	NUM
admet-130	205	2	(	(	PUNCT
admet-130	205	3	2008	2008	NUM
admet-130	205	4	)	)	PUNCT
admet-130	205	5	459	459	NUM
admet-130	205	6	-	-	SYM
admet-130	205	7	472	472	NUM
admet-130	205	8	.	.	PUNCT
admet-130	206	1	[	[	X
admet-130	206	2	37	37	NUM
admet-130	206	3	]	]	PUNCT
admet-130	206	4	s.	s.	PROPN
admet-130	206	5	wu	wu	PROPN
admet-130	206	6	,	,	PUNCT
admet-130	206	7	j.	j.	PROPN
admet-130	206	8	ren	ren	PROPN
admet-130	206	9	,	,	PUNCT
admet-130	206	10	neurosci	neurosci	PROPN
admet-130	206	11	.	.	PUNCT
admet-130	207	1	lett	lett	PROPN
admet-130	207	2	.	.	PUNCT
admet-130	208	1	394	394	NUM
admet-130	208	2	(	(	PUNCT
admet-130	208	3	2006	2006	NUM
admet-130	208	4	)	)	PUNCT
admet-130	208	5	158	158	NUM
admet-130	208	6	-	-	SYM
admet-130	208	7	162	162	NUM
admet-130	208	8	.	.	PUNCT
admet-130	209	1	[	[	X
admet-130	209	2	38	38	NUM
admet-130	209	3	]	]	PUNCT
admet-130	209	4	s.	s.	PROPN
admet-130	209	5	gadau	gadau	PROPN
admet-130	209	6	,	,	PUNCT
admet-130	209	7	c.	c.	PROPN
admet-130	209	8	emanueli	emanueli	PROPN
admet-130	209	9	,	,	PUNCT
admet-130	209	10	s.	s.	PROPN
admet-130	209	11	van	van	PROPN
admet-130	209	12	linthout	linthout	PROPN
admet-130	209	13	,	,	PUNCT
admet-130	209	14	g.	g.	PROPN
admet-130	209	15	graiani	graiani	PROPN
admet-130	209	16	,	,	PUNCT
admet-130	209	17	m.	m.	NOUN
admet-130	209	18	todaro	todaro	NOUN
admet-130	209	19	,	,	PUNCT
admet-130	209	20	m.	m.	NOUN
admet-130	209	21	meloni	meloni	PROPN
admet-130	209	22	,	,	PUNCT
admet-130	209	23	i.	i.	PROPN
admet-130	209	24	campesi	campesi	PROPN
admet-130	209	25	,	,	PUNCT
admet-130	209	26	g.	g.	PROPN
admet-130	209	27	invernici	invernici	PROPN
admet-130	209	28	,	,	PUNCT
admet-130	209	29	f.	f.	PROPN
admet-130	209	30	spillmann	spillmann	PROPN
admet-130	209	31	,	,	PUNCT
admet-130	209	32	k.	k.	PROPN
admet-130	209	33	ward	ward	PROPN
admet-130	209	34	,	,	PUNCT
admet-130	209	35	p.	p.	PROPN
admet-130	209	36	madeddu	madeddu	NOUN
admet-130	209	37	,	,	PUNCT
admet-130	209	38	diabetologia	diabetologia	NOUN
admet-130	209	39	49	49	NUM
admet-130	209	40	(	(	PUNCT
admet-130	209	41	2006	2006	NUM
admet-130	209	42	)	)	PUNCT
admet-130	209	43	405	405	NUM
admet-130	209	44	-	-	SYM
admet-130	209	45	420	420	NUM
admet-130	209	46	.	.	PUNCT
admet-130	210	1	[	[	X
admet-130	210	2	39	39	NUM
admet-130	210	3	]	]	X
admet-130	210	4	g.m	g.m	PROPN
admet-130	210	5	.	.	PROPN
admet-130	210	6	sanchez	sanchez	PROPN
admet-130	210	7	-	-	PUNCT
admet-130	210	8	ramirez	ramirez	PROPN
admet-130	210	9	,	,	PUNCT
admet-130	210	10	n.l	n.l	PROPN
admet-130	210	11	.	.	PROPN
admet-130	210	12	caram	caram	PROPN
admet-130	210	13	-	-	PUNCT
admet-130	210	14	salas	salas	PROPN
admet-130	210	15	,	,	PUNCT
admet-130	210	16	h.i	h.i	PROPN
admet-130	210	17	.	.	PROPN
admet-130	210	18	rocha	rocha	PROPN
admet-130	210	19	-	-	PUNCT
admet-130	210	20	gonzalez	gonzalez	PROPN
admet-130	210	21	,	,	PUNCT
admet-130	210	22	g.c	g.c	PROPN
admet-130	210	23	.	.	PROPN
admet-130	210	24	vidal	vidal	NOUN
admet-130	210	25	-	-	PUNCT
admet-130	210	26	cantu	cantu	PROPN
admet-130	210	27	,	,	PUNCT
admet-130	210	28	r.	r.	PROPN
admet-130	210	29	medinasantillan	medinasantillan	PROPN
admet-130	210	30	,	,	PUNCT
admet-130	210	31	g.	g.	PROPN
admet-130	210	32	reyes	reyes	PROPN
admet-130	210	33	-	-	PUNCT
admet-130	210	34	garcia	garcia	PROPN
admet-130	210	35	,	,	PUNCT
admet-130	210	36	eur	eur	PROPN
admet-130	210	37	.	.	PUNCT
admet-130	210	38	j.	j.	PROPN
admet-130	210	39	pharmacol	pharmacol	PROPN
admet-130	210	40	.	.	PUNCT
admet-130	211	1	530	530	NUM
admet-130	211	2	(	(	PUNCT
admet-130	211	3	2006	2006	NUM
admet-130	211	4	)	)	PUNCT
admet-130	211	5	48	48	NUM
admet-130	211	6	-	-	SYM
admet-130	211	7	53	53	NUM
admet-130	211	8	.	.	PUNCT
admet-130	212	1	[	[	X
admet-130	212	2	40	40	NUM
admet-130	212	3	]	]	X
admet-130	212	4	r.g	r.g	PROPN
admet-130	212	5	.	.	PROPN
admet-130	212	6	katare	katare	PROPN
admet-130	212	7	,	,	PUNCT
admet-130	212	8	a.	a.	PROPN
admet-130	212	9	caporali	caporali	PROPN
admet-130	212	10	,	,	PUNCT
admet-130	212	11	a.	a.	NOUN
admet-130	212	12	oikawa	oikawa	PROPN
admet-130	212	13	,	,	PUNCT
admet-130	212	14	m.	m.	NOUN
admet-130	212	15	meloni	meloni	PROPN
admet-130	212	16	,	,	PUNCT
admet-130	212	17	c.	c.	PROPN
admet-130	212	18	emanueli	emanueli	PROPN
admet-130	212	19	,	,	PUNCT
admet-130	212	20	p.	p.	PROPN
admet-130	212	21	madeddu	madeddu	NOUN
admet-130	212	22	,	,	PUNCT
admet-130	212	23	circ	circ	NOUN
admet-130	212	24	.	.	PUNCT
admet-130	213	1	heart	heart	NOUN
admet-130	213	2	fail	fail	VERB
admet-130	213	3	.	.	PUNCT
admet-130	214	1	3	3	NUM
admet-130	214	2	(	(	PUNCT
admet-130	214	3	2010	2010	NUM
admet-130	214	4	)	)	PUNCT
admet-130	214	5	294	294	NUM
admet-130	214	6	-	-	SYM
admet-130	214	7	305	305	NUM
admet-130	214	8	.	.	PUNCT
admet-130	215	1	[	[	X
admet-130	215	2	41	41	NUM
admet-130	215	3	]	]	X
admet-130	215	4	r.	r.	PROPN
admet-130	215	5	katare	katare	PROPN
admet-130	215	6	,	,	PUNCT
admet-130	215	7	a.	a.	PROPN
admet-130	215	8	caporali	caporali	PROPN
admet-130	215	9	,	,	PUNCT
admet-130	215	10	c.	c.	PROPN
admet-130	215	11	emanueli	emanueli	PROPN
admet-130	215	12	,	,	PUNCT
admet-130	215	13	p.	p.	PROPN
admet-130	215	14	madeddu	madeddu	PROPN
admet-130	215	15	,	,	PUNCT
admet-130	215	16	j.	j.	PROPN
admet-130	215	17	mol	mol	PROPN
admet-130	215	18	.	.	PROPN
admet-130	216	1	cell	cell	NOUN
admet-130	216	2	cardiol	cardiol	NOUN
admet-130	216	3	.	.	PUNCT
admet-130	217	1	49	49	NUM
admet-130	217	2	(	(	PUNCT
admet-130	217	3	2010	2010	NUM
admet-130	217	4	)	)	PUNCT
admet-130	217	5	625	625	NUM
admet-130	217	6	-	-	SYM
admet-130	217	7	638	638	NUM
admet-130	217	8	.	.	PUNCT
admet-130	218	1	[	[	X
admet-130	218	2	42	42	NUM
admet-130	218	3	]	]	X
admet-130	218	4	y.	y.	PROPN
admet-130	218	5	kohda	kohda	PROPN
admet-130	218	6	,	,	PUNCT
admet-130	218	7	m.	m.	NOUN
admet-130	218	8	umeki	umeki	PROPN
admet-130	218	9	,	,	PUNCT
admet-130	218	10	t.	t.	PROPN
admet-130	218	11	kono	kono	PROPN
admet-130	218	12	,	,	PUNCT
admet-130	218	13	f.	f.	PROPN
admet-130	218	14	terasaki	terasaki	PROPN
admet-130	218	15	,	,	PUNCT
admet-130	218	16	h.	h.	PROPN
admet-130	218	17	matsumura	matsumura	PROPN
admet-130	218	18	,	,	PUNCT
admet-130	218	19	t.	t.	PROPN
admet-130	218	20	tanaka	tanaka	PROPN
admet-130	218	21	,	,	PUNCT
admet-130	218	22	j.	j.	PROPN
admet-130	218	23	pharmacol	pharmacol	PROPN
admet-130	218	24	.	.	PUNCT
admet-130	219	1	sci	sci	PROPN
admet-130	219	2	.	.	PROPN
admet-130	220	1	113	113	NUM
admet-130	220	2	(	(	PUNCT
admet-130	220	3	2010	2010	NUM
admet-130	220	4	)	)	PUNCT
admet-130	220	5	343	343	NUM
admet-130	220	6	-	-	SYM
admet-130	220	7	352	352	NUM
admet-130	220	8	.	.	PUNCT
admet-130	221	1	[	[	X
admet-130	221	2	43	43	NUM
admet-130	221	3	]	]	X
admet-130	221	4	r.	r.	PROPN
admet-130	221	5	katare	katare	PROPN
admet-130	221	6	,	,	PUNCT
admet-130	221	7	a.	a.	NOUN
admet-130	221	8	oikawa	oikawa	PROPN
admet-130	221	9	,	,	PUNCT
admet-130	221	10	d.	d.	PROPN
admet-130	221	11	cesselli	cesselli	PROPN
admet-130	221	12	,	,	PUNCT
admet-130	221	13	a.p	a.p	PROPN
admet-130	221	14	.	.	PROPN
admet-130	221	15	beltrami	beltrami	PROPN
admet-130	221	16	,	,	PUNCT
admet-130	221	17	e.	e.	PROPN
admet-130	221	18	avolio	avolio	PROPN
admet-130	221	19	,	,	PUNCT
admet-130	221	20	d.	d.	PROPN
admet-130	221	21	muthukrishnan	muthukrishnan	PROPN
admet-130	221	22	,	,	PUNCT
admet-130	221	23	p.e	p.e	PROPN
admet-130	221	24	.	.	PROPN
admet-130	221	25	munasinghe	munasinghe	PROPN
admet-130	221	26	,	,	PUNCT
admet-130	221	27	g.	g.	PROPN
admet-130	221	28	angelini	angelini	PROPN
admet-130	221	29	,	,	PUNCT
admet-130	221	30	c.	c.	PROPN
admet-130	221	31	emanueli	emanueli	PROPN
admet-130	221	32	,	,	PUNCT
admet-130	221	33	p.	p.	PROPN
admet-130	221	34	madeddu	madeddu	PROPN
admet-130	221	35	,	,	PUNCT
admet-130	221	36	cardiovasc	cardiovasc	PROPN
admet-130	221	37	.	.	PUNCT
admet-130	222	1	res	re	NOUN
admet-130	222	2	.	.	PROPN
admet-130	223	1	97	97	NUM
admet-130	223	2	(	(	PUNCT
admet-130	223	3	2013	2013	NUM
admet-130	223	4	)	)	PUNCT
admet-130	223	5	55	55	NUM
admet-130	223	6	-	-	SYM
admet-130	223	7	65	65	NUM
admet-130	223	8	.	.	PUNCT
admet-130	224	1	[	[	X
admet-130	224	2	44	44	NUM
admet-130	224	3	]	]	PUNCT
admet-130	224	4	h.	h.	PROPN
admet-130	224	5	stracke	stracke	PROPN
admet-130	224	6	,	,	PUNCT
admet-130	224	7	a.	a.	PROPN
admet-130	224	8	lindemann	lindemann	PROPN
admet-130	224	9	,	,	PUNCT
admet-130	224	10	k.	k.	PROPN
admet-130	224	11	federlin	federlin	PROPN
admet-130	224	12	,	,	PUNCT
admet-130	224	13	exp	exp	NOUN
admet-130	224	14	.	.	PUNCT
admet-130	225	1	clin	clin	PROPN
admet-130	225	2	.	.	PUNCT
admet-130	225	3	endocrinol	endocrinol	NOUN
admet-130	225	4	.	.	PUNCT
admet-130	226	1	diabetes	diabetes	NOUN
admet-130	226	2	104	104	NUM
admet-130	226	3	(	(	PUNCT
admet-130	226	4	1996	1996	NUM
admet-130	226	5	)	)	PUNCT
admet-130	226	6	311	311	NUM
admet-130	226	7	-	-	SYM
admet-130	226	8	316	316	NUM
admet-130	226	9	.	.	PUNCT
admet-130	227	1	[	[	X
admet-130	227	2	45	45	NUM
admet-130	227	3	]	]	X
admet-130	227	4	e.	e.	PROPN
admet-130	227	5	haupt	haupt	PROPN
admet-130	227	6	,	,	PUNCT
admet-130	227	7	h.	h.	PROPN
admet-130	227	8	ledermann	ledermann	PROPN
admet-130	227	9	,	,	PUNCT
admet-130	227	10	w.	w.	PROPN
admet-130	227	11	köpcke	köpcke	PROPN
admet-130	227	12	,	,	PUNCT
admet-130	227	13	int	int	PROPN
admet-130	227	14	.	.	PUNCT
admet-130	228	1	j.	j.	PROPN
admet-130	228	2	clin	clin	PROPN
admet-130	228	3	.	.	PUNCT
admet-130	229	1	pharmacol	pharmacol	PROPN
admet-130	229	2	.	.	PUNCT
admet-130	230	1	ther	ther	PROPN
admet-130	230	2	.	.	PUNCT
admet-130	231	1	43	43	NUM
admet-130	231	2	(	(	PUNCT
admet-130	231	3	2005	2005	NUM
admet-130	231	4	)	)	PUNCT
admet-130	231	5	71	71	NUM
admet-130	231	6	-	-	SYM
admet-130	231	7	77	77	NUM
admet-130	231	8	.	.	PUNCT
admet-130	232	1	[	[	X
admet-130	232	2	46	46	NUM
admet-130	232	3	]	]	PUNCT
admet-130	232	4	s.	s.	PROPN
admet-130	232	5	arora	arora	PROPN
admet-130	232	6	,	,	PUNCT
admet-130	232	7	a.	a.	PROPN
admet-130	232	8	lidor	lidor	PROPN
admet-130	232	9	,	,	PUNCT
admet-130	232	10	c.j	c.j	PROPN
admet-130	232	11	.	.	PROPN
admet-130	232	12	abularrage	abularrage	NOUN
admet-130	232	13	,	,	PUNCT
admet-130	232	14	j.m	j.m	PROPN
admet-130	232	15	.	.	PROPN
admet-130	232	16	weiswasser	weiswasser	NOUN
admet-130	232	17	,	,	PUNCT
admet-130	232	18	e.	e.	PROPN
admet-130	232	19	nylen	nylen	PROPN
admet-130	232	20	,	,	PUNCT
admet-130	232	21	d.	d.	PROPN
admet-130	232	22	kellicut	kellicut	PROPN
admet-130	232	23	,	,	PUNCT
admet-130	232	24	a.n	a.n	PROPN
admet-130	232	25	.	.	PROPN
admet-130	232	26	sidawy	sidawy	PROPN
admet-130	232	27	,	,	PUNCT
admet-130	232	28	ann	ann	PROPN
admet-130	232	29	.	.	PROPN
admet-130	232	30	vasc	vasc	PROPN
admet-130	232	31	.	.	PROPN
admet-130	232	32	surg	surg	PROPN
admet-130	232	33	.	.	PUNCT
admet-130	233	1	20	20	NUM
admet-130	233	2	(	(	PUNCT
admet-130	233	3	2006	2006	NUM
admet-130	233	4	)	)	PUNCT
admet-130	233	5	653	653	NUM
admet-130	233	6	-	-	SYM
admet-130	233	7	658	658	NUM
admet-130	233	8	.	.	PUNCT
admet-130	234	1	[	[	X
admet-130	234	2	47	47	NUM
admet-130	234	3	]	]	PUNCT
admet-130	234	4	x.	x.	NOUN
admet-130	234	5	du	du	PROPN
admet-130	234	6	,	,	PUNCT
admet-130	234	7	d.	d.	PROPN
admet-130	234	8	edelstein	edelstein	PROPN
admet-130	234	9	,	,	PUNCT
admet-130	234	10	m.	m.	PROPN
admet-130	234	11	brownlee	brownlee	PROPN
admet-130	234	12	,	,	PUNCT
admet-130	234	13	diabetologia	diabetologia	NOUN
admet-130	234	14	51	51	NUM
admet-130	234	15	(	(	PUNCT
admet-130	234	16	2008	2008	NUM
admet-130	234	17	)	)	PUNCT
admet-130	234	18	1930	1930	NUM
admet-130	234	19	-	-	SYM
admet-130	234	20	1932	1932	NUM
admet-130	234	21	.	.	PUNCT
admet-130	235	1	[	[	X
admet-130	235	2	48	48	NUM
admet-130	235	3	]	]	X
admet-130	235	4	n.	n.	PROPN
admet-130	235	5	schupp	schupp	PROPN
admet-130	235	6	,	,	PUNCT
admet-130	235	7	e.m	e.m	PROPN
admet-130	235	8	.	.	PROPN
admet-130	235	9	dette	dette	PROPN
admet-130	235	10	,	,	PUNCT
admet-130	235	11	u.	u.	PROPN
admet-130	235	12	schmid	schmid	PROPN
admet-130	235	13	,	,	PUNCT
admet-130	235	14	u.	u.	PROPN
admet-130	235	15	bahner	bahner	NOUN
admet-130	235	16	,	,	PUNCT
admet-130	235	17	m.	m.	NOUN
admet-130	235	18	winkler	winkler	PROPN
admet-130	235	19	,	,	PUNCT
admet-130	235	20	a.	a.	PROPN
admet-130	235	21	heidland	heidland	PROPN
admet-130	235	22	,	,	PUNCT
admet-130	235	23	h.	h.	PROPN
admet-130	235	24	stopper	stopper	NOUN
admet-130	235	25	,	,	PUNCT
admet-130	235	26	naunyn	naunyn	PROPN
admet-130	235	27	schmiedebergs	schmiedebergs	PROPN
admet-130	235	28	arch	arch	VERB
admet-130	235	29	.	.	PUNCT
admet-130	236	1	pharmacol	pharmacol	NOUN
admet-130	236	2	.	.	PUNCT
admet-130	237	1	378	378	NUM
admet-130	237	2	(	(	PUNCT
admet-130	237	3	2008	2008	NUM
admet-130	237	4	)	)	PUNCT
admet-130	237	5	283	283	NUM
admet-130	237	6	-	-	SYM
admet-130	237	7	291	291	NUM
admet-130	237	8	.	.	PUNCT
admet-130	238	1	[	[	X
admet-130	238	2	49	49	NUM
admet-130	238	3	]	]	PUNCT
admet-130	238	4	s.	s.	PROPN
admet-130	238	5	riaz	riaz	PROPN
admet-130	238	6	,	,	PUNCT
admet-130	238	7	v.	v.	PROPN
admet-130	238	8	skinner	skinner	PROPN
admet-130	238	9	,	,	PUNCT
admet-130	238	10	s.k	s.k	PROPN
admet-130	238	11	.	.	PROPN
admet-130	238	12	srai	srai	PROPN
admet-130	238	13	,	,	PUNCT
admet-130	238	14	j.	j.	PROPN
admet-130	238	15	pharm	pharm	PROPN
admet-130	238	16	.	.	PUNCT
admet-130	238	17	biomed	biome	VERB
admet-130	238	18	.	.	PUNCT
admet-130	239	1	anal	anal	ADJ
admet-130	239	2	.	.	PUNCT
admet-130	240	1	54	54	NUM
admet-130	240	2	(	(	PUNCT
admet-130	240	3	2011	2011	NUM
admet-130	240	4	)	)	PUNCT
admet-130	240	5	817	817	NUM
admet-130	240	6	-	-	SYM
admet-130	240	7	825	825	NUM
admet-130	240	8	.	.	PUNCT
admet-130	241	1	[	[	X
admet-130	241	2	50	50	NUM
admet-130	241	3	]	]	X
admet-130	241	4	n.	n.	NOUN
admet-130	241	5	rabbani	rabbani	PROPN
admet-130	241	6	,	,	PUNCT
admet-130	241	7	s.s	s.s	PROPN
admet-130	241	8	.	.	PROPN
admet-130	241	9	alam	alam	PROPN
admet-130	241	10	,	,	PUNCT
admet-130	241	11	s.	s.	PROPN
admet-130	241	12	riaz	riaz	PROPN
admet-130	241	13	,	,	PUNCT
admet-130	241	14	j.r	j.r	PROPN
admet-130	241	15	.	.	PROPN
admet-130	241	16	larkin	larkin	PROPN
admet-130	241	17	,	,	PUNCT
admet-130	241	18	m.w	m.w	PROPN
admet-130	241	19	.	.	PROPN
admet-130	241	20	akhtar	akhtar	PROPN
admet-130	241	21	,	,	PUNCT
admet-130	241	22	t.	t.	PROPN
admet-130	241	23	shafi	shafi	PROPN
admet-130	241	24	,	,	PUNCT
admet-130	241	25	p.j	p.j	PROPN
admet-130	241	26	.	.	PROPN
admet-130	241	27	thornalley	thornalley	PROPN
admet-130	241	28	,	,	PUNCT
admet-130	241	29	diabetologia	diabetologia	NOUN
admet-130	241	30	52	52	NUM
admet-130	241	31	(	(	PUNCT
admet-130	241	32	2009	2009	NUM
admet-130	241	33	)	)	PUNCT
admet-130	241	34	208	208	NUM
admet-130	241	35	-	-	SYM
admet-130	241	36	212	212	NUM
admet-130	241	37	.	.	PUNCT
admet-130	242	1	admet	admet	PROPN
admet-130	242	2	&	&	CCONJ
admet-130	242	3	dmpk	dmpk	PROPN
admet-130	242	4	2(4	2(4	NUM
admet-130	242	5	)	)	PUNCT
admet-130	242	6	(	(	PUNCT
admet-130	242	7	2014	2014	NUM
admet-130	242	8	)	)	PUNCT
admet-130	242	9	272	272	NUM
admet-130	242	10	-	-	SYM
admet-130	242	11	281	281	NUM
admet-130	242	12	transderamal	transderamal	ADJ
admet-130	242	13	delivery	delivery	NOUN
admet-130	242	14	of	of	ADP
admet-130	242	15	benfotiamine	benfotiamine	ADJ
admet-130	242	16	in	in	ADP
admet-130	242	17	an	an	DET
admet-130	242	18	animal	animal	NOUN
admet-130	242	19	model	model	NOUN
admet-130	242	20	doi	doi	NOUN
admet-130	242	21	:	:	PUNCT
admet-130	242	22	10.5599	10.5599	NUM
admet-130	242	23	/	/	SYM
admet-130	242	24	admet.2.4.130	admet.2.4.130	ADP
admet-130	242	25	281	281	NUM
admet-130	242	26	[	[	X
admet-130	242	27	51	51	NUM
admet-130	242	28	]	]	PUNCT
admet-130	242	29	a.	a.	NOUN
admet-130	242	30	alkhalaf	alkhalaf	PROPN
admet-130	242	31	,	,	PUNCT
admet-130	242	32	a.	a.	NOUN
admet-130	242	33	klooster	klooster	PROPN
admet-130	242	34	,	,	PUNCT
admet-130	242	35	w.	w.	PROPN
admet-130	242	36	van	van	PROPN
admet-130	242	37	oeveren	oeveren	PROPN
admet-130	242	38	,	,	PUNCT
admet-130	242	39	u.	u.	PROPN
admet-130	242	40	achenbach	achenbach	PROPN
admet-130	242	41	,	,	PUNCT
admet-130	242	42	n.	n.	PROPN
admet-130	242	43	kleefstra	kleefstra	PROPN
admet-130	242	44	,	,	PUNCT
admet-130	242	45	r.j	r.j	PROPN
admet-130	242	46	.	.	PROPN
admet-130	242	47	slingerland	slingerland	PROPN
admet-130	242	48	,	,	PUNCT
admet-130	242	49	g.s	g.s	PROPN
admet-130	242	50	.	.	PROPN
admet-130	242	51	mijnhout	mijnhout	PROPN
admet-130	242	52	,	,	PUNCT
admet-130	242	53	h.j	h.j	PROPN
admet-130	242	54	.	.	PROPN
admet-130	242	55	bilo	bilo	PROPN
admet-130	242	56	,	,	PUNCT
admet-130	242	57	r.o	r.o	PROPN
admet-130	242	58	.	.	PROPN
admet-130	242	59	gans	gans	PROPN
admet-130	242	60	,	,	PUNCT
admet-130	242	61	g.j	g.j	PROPN
admet-130	242	62	.	.	PROPN
admet-130	242	63	navis	navis	PROPN
admet-130	242	64	,	,	PUNCT
admet-130	242	65	s.j	s.j	PROPN
admet-130	242	66	.	.	PROPN
admet-130	242	67	bakker	bakker	PROPN
admet-130	242	68	,	,	PUNCT
admet-130	242	69	diabetes	diabetes	NOUN
admet-130	242	70	care	care	NOUN
admet-130	242	71	,	,	PUNCT
admet-130	242	72	33	33	NUM
admet-130	242	73	(	(	PUNCT
admet-130	242	74	2010	2010	NUM
admet-130	242	75	)	)	PUNCT
admet-130	242	76	1598	1598	NUM
admet-130	242	77	-	-	SYM
admet-130	242	78	1601	1601	NUM
admet-130	242	79	.	.	PUNCT
admet-130	243	1	[	[	X
admet-130	243	2	52	52	NUM
admet-130	243	3	]	]	PUNCT
admet-130	243	4	m.	m.	PROPN
admet-130	243	5	gonzález	gonzález	PROPN
admet-130	243	6	-	-	PUNCT
admet-130	243	7	ortiz	ortiz	PROPN
admet-130	243	8	,	,	PUNCT
admet-130	243	9	e.	e.	PROPN
admet-130	243	10	martínez	martínez	PROPN
admet-130	243	11	-	-	PUNCT
admet-130	243	12	abundis	abundis	PROPN
admet-130	243	13	,	,	PUNCT
admet-130	243	14	j.a	j.a	PROPN
admet-130	243	15	.	.	PROPN
admet-130	243	16	robles	roble	NOUN
admet-130	243	17	-	-	PUNCT
admet-130	243	18	cervantes	cervante	NOUN
admet-130	243	19	,	,	PUNCT
admet-130	243	20	v.	v.	ADP
admet-130	243	21	ramírez	ramírez	NOUN
admet-130	243	22	-	-	PUNCT
admet-130	243	23	ramírez	ramírez	NOUN
admet-130	243	24	,	,	PUNCT
admet-130	243	25	m.g	m.g	PROPN
admet-130	243	26	.	.	PROPN
admet-130	243	27	ramos	ramos	PROPN
admet-130	243	28	-	-	PUNCT
admet-130	243	29	zavala	zavala	PROPN
admet-130	243	30	,	,	PUNCT
admet-130	243	31	eur	eur	PROPN
admet-130	243	32	.	.	PUNCT
admet-130	243	33	j.	j.	PROPN
admet-130	243	34	nutr	nutr	PROPN
admet-130	243	35	.	.	PROPN
admet-130	243	36	50	50	NUM
admet-130	243	37	(	(	PUNCT
admet-130	243	38	2011	2011	NUM
admet-130	243	39	)	)	PUNCT
admet-130	243	40	145	145	NUM
admet-130	243	41	-	-	SYM
admet-130	243	42	149	149	NUM
admet-130	243	43	.	.	PUNCT
admet-130	244	1	[	[	X
admet-130	244	2	53	53	NUM
admet-130	244	3	]	]	PUNCT
admet-130	244	4	a.	a.	NOUN
admet-130	244	5	alkhalaf	alkhalaf	PROPN
admet-130	244	6	,	,	PUNCT
admet-130	244	7	n.	n.	PROPN
admet-130	244	8	kleefstra	kleefstra	PROPN
admet-130	244	9	,	,	PUNCT
admet-130	244	10	k.h	k.h	PROPN
admet-130	244	11	.	.	PROPN
admet-130	244	12	groenier	groenier	PROPN
admet-130	244	13	,	,	PUNCT
admet-130	244	14	h.j	h.j	PROPN
admet-130	244	15	.	.	PROPN
admet-130	244	16	bilo	bilo	PROPN
admet-130	244	17	,	,	PUNCT
admet-130	244	18	r.o	r.o	PROPN
admet-130	244	19	.	.	PROPN
admet-130	244	20	gans	gans	PROPN
admet-130	244	21	,	,	PUNCT
admet-130	244	22	p.	p.	NOUN
admet-130	244	23	heeringa	heeringa	PROPN
admet-130	244	24	,	,	PUNCT
admet-130	244	25	j.l	j.l	PROPN
admet-130	244	26	.	.	PROPN
admet-130	244	27	scheijen	scheijen	PROPN
admet-130	244	28	,	,	PUNCT
admet-130	244	29	c.g	c.g	PROPN
admet-130	244	30	.	.	PROPN
admet-130	244	31	schalkwijk	schalkwijk	PROPN
admet-130	244	32	,	,	PUNCT
admet-130	244	33	g.j	g.j	PROPN
admet-130	244	34	.	.	PROPN
admet-130	244	35	navis	navis	PROPN
admet-130	244	36	,	,	PUNCT
admet-130	244	37	s.j	s.j	PROPN
admet-130	244	38	.	.	PROPN
admet-130	244	39	bakker	bakker	PROPN
admet-130	244	40	,	,	PUNCT
admet-130	244	41	plos	plos	PROPN
admet-130	244	42	one	one	NUM
admet-130	244	43	7	7	NUM
admet-130	244	44	(	(	PUNCT
admet-130	244	45	2012	2012	NUM
admet-130	244	46	)	)	PUNCT
admet-130	245	1	e40427	e40427	NOUN
admet-130	245	2	.	.	PUNCT
admet-130	246	1	[	[	X
admet-130	246	2	54	54	NUM
admet-130	246	3	]	]	SYM
admet-130	246	4	d.a	d.a	PROPN
admet-130	246	5	.	.	PROPN
admet-130	246	6	fraser	fraser	PROPN
admet-130	246	7	,	,	PUNCT
admet-130	246	8	l.m	l.m	PROPN
admet-130	246	9	.	.	PROPN
admet-130	246	10	diep	diep	PROPN
admet-130	246	11	,	,	PUNCT
admet-130	246	12	i.a	i.a	PROPN
admet-130	246	13	.	.	PROPN
admet-130	246	14	hovden	hovden	PROPN
admet-130	246	15	,	,	PUNCT
admet-130	246	16	k.b	k.b	PROPN
admet-130	246	17	.	.	PROPN
admet-130	246	18	nilsen	nilsen	PROPN
admet-130	246	19	,	,	PUNCT
admet-130	246	20	k.a	k.a	PROPN
admet-130	246	21	.	.	PROPN
admet-130	246	22	sveen	sveen	PROPN
admet-130	246	23	,	,	PUNCT
admet-130	246	24	i.	i.	NOUN
admet-130	246	25	seljeflot	seljeflot	PROPN
admet-130	246	26	,	,	PUNCT
admet-130	246	27	k.f	k.f	PROPN
admet-130	246	28	.	.	PROPN
admet-130	246	29	hanssen	hanssen	PROPN
admet-130	246	30	,	,	PUNCT
admet-130	246	31	diabetes	diabetes	NOUN
admet-130	246	32	care	care	VERB
admet-130	246	33	35	35	NUM
admet-130	246	34	(	(	PUNCT
admet-130	246	35	2012	2012	NUM
admet-130	246	36	)	)	PUNCT
admet-130	246	37	1095	1095	NUM
admet-130	246	38	-	-	SYM
admet-130	246	39	1097	1097	NUM
admet-130	246	40	.	.	PUNCT
admet-130	247	1	[	[	X
admet-130	247	2	55	55	NUM
admet-130	247	3	]	]	X
admet-130	247	4	f.c	f.c	PROPN
admet-130	247	5	.	.	PROPN
admet-130	247	6	polizzi	polizzi	PROPN
admet-130	247	7	,	,	PUNCT
admet-130	247	8	g.	g.	PROPN
admet-130	247	9	andican	andican	PROPN
admet-130	247	10	,	,	PUNCT
admet-130	247	11	e.	e.	PROPN
admet-130	247	12	çetin	çetin	PROPN
admet-130	247	13	,	,	PUNCT
admet-130	247	14	s.	s.	PROPN
admet-130	247	15	civelek	civelek	PROPN
admet-130	247	16	,	,	PUNCT
admet-130	247	17	v.	v.	CCONJ
admet-130	247	18	yumuk	yumuk	NOUN
admet-130	247	19	,	,	PUNCT
admet-130	247	20	g.	g.	PROPN
admet-130	247	21	burçak	burçak	PROPN
admet-130	247	22	,	,	PUNCT
admet-130	247	23	exp	exp	PROPN
admet-130	247	24	.	.	PUNCT
admet-130	248	1	clin	clin	PROPN
admet-130	248	2	.	.	PUNCT
admet-130	248	3	endocrinol	endocrinol	NOUN
admet-130	248	4	.	.	PUNCT
admet-130	249	1	diabetes	diabetes	NOUN
admet-130	249	2	120	120	NUM
admet-130	249	3	(	(	PUNCT
admet-130	249	4	2012	2012	NUM
admet-130	249	5	)	)	PUNCT
admet-130	249	6	329	329	NUM
admet-130	249	7	-	-	SYM
admet-130	249	8	334	334	NUM
admet-130	249	9	.	.	PUNCT
admet-130	250	1	[	[	X
admet-130	250	2	56	56	NUM
admet-130	250	3	]	]	PUNCT
admet-130	250	4	a.	a.	NOUN
admet-130	250	5	stirban	stirban	PROPN
admet-130	250	6	,	,	PUNCT
admet-130	250	7	a.	a.	NOUN
admet-130	250	8	pop	pop	NOUN
admet-130	250	9	,	,	PUNCT
admet-130	250	10	a.	a.	NOUN
admet-130	250	11	fischer	fischer	PROPN
admet-130	250	12	,	,	PUNCT
admet-130	250	13	s.	s.	PROPN
admet-130	250	14	heckermann	heckermann	PROPN
admet-130	250	15	,	,	PUNCT
admet-130	250	16	d.	d.	PROPN
admet-130	250	17	tschoepe	tschoepe	PROPN
admet-130	250	18	,	,	PUNCT
admet-130	250	19	diabetes	diabetes	NOUN
admet-130	250	20	technol	technol	NOUN
admet-130	250	21	.	.	PUNCT
admet-130	251	1	ther	ther	PROPN
admet-130	251	2	.	.	PUNCT
admet-130	252	1	15	15	NUM
admet-130	252	2	(	(	PUNCT
admet-130	252	3	2013	2013	NUM
admet-130	252	4	)	)	PUNCT
admet-130	252	5	733737	733737	NUM
admet-130	252	6	.	.	PUNCT
admet-130	253	1	[	[	X
admet-130	253	2	57	57	NUM
admet-130	253	3	]	]	PUNCT
admet-130	253	4	a.	a.	NOUN
admet-130	253	5	stirban	stirban	PROPN
admet-130	253	6	,	,	PUNCT
admet-130	253	7	a.	a.	NOUN
admet-130	253	8	pop	pop	PROPN
admet-130	253	9	,	,	PUNCT
admet-130	253	10	d.	d.	PROPN
admet-130	253	11	tschoepe	tschoepe	PROPN
admet-130	253	12	,	,	PUNCT
admet-130	253	13	diabet	diabet	PROPN
admet-130	253	14	.	.	PUNCT
admet-130	253	15	med	med	PROPN
admet-130	253	16	.	.	PROPN
admet-130	254	1	30	30	NUM
admet-130	255	1	(	(	PUNCT
admet-130	255	2	2013	2013	NUM
admet-130	255	3	)	)	PUNCT
admet-130	255	4	1204	1204	NUM
admet-130	255	5	-	-	SYM
admet-130	255	6	1208	1208	NUM
admet-130	255	7	.	.	PUNCT
admet-130	256	1	[	[	X
admet-130	256	2	58	58	NUM
admet-130	256	3	]	]	X
admet-130	256	4	e.	e.	PROPN
admet-130	256	5	berrone	berrone	PROPN
admet-130	256	6	,	,	PUNCT
admet-130	256	7	e.	e.	PROPN
admet-130	256	8	beltramo	beltramo	PROPN
admet-130	256	9	,	,	PUNCT
admet-130	256	10	c.	c.	PROPN
admet-130	256	11	solimine	solimine	PROPN
admet-130	256	12	,	,	PUNCT
admet-130	256	13	a.u	a.u	PROPN
admet-130	256	14	.	.	NOUN
admet-130	256	15	ape	ape	NOUN
admet-130	256	16	,	,	PUNCT
admet-130	256	17	m.	m.	NOUN
admet-130	256	18	porta	porta	PROPN
admet-130	256	19	,	,	PUNCT
admet-130	256	20	j.	j.	PROPN
admet-130	256	21	biol	biol	PROPN
admet-130	256	22	.	.	PUNCT
admet-130	257	1	chem	chem	PROPN
admet-130	257	2	.	.	PUNCT
admet-130	258	1	281	281	NUM
admet-130	258	2	(	(	PUNCT
admet-130	258	3	2006	2006	NUM
admet-130	258	4	)	)	PUNCT
admet-130	258	5	9307	9307	NUM
admet-130	258	6	-	-	SYM
admet-130	258	7	9313	9313	NUM
admet-130	258	8	.	.	PUNCT
admet-130	259	1	[	[	X
admet-130	259	2	59	59	NUM
admet-130	259	3	]	]	PUNCT
admet-130	259	4	v.	v.	CCONJ
admet-130	259	5	marchetti	marchetti	PROPN
admet-130	259	6	,	,	PUNCT
admet-130	259	7	r.	r.	PROPN
admet-130	259	8	menghini	menghini	PROPN
admet-130	259	9	,	,	PUNCT
admet-130	259	10	s.	s.	PROPN
admet-130	259	11	rizza	rizza	PROPN
admet-130	259	12	,	,	PUNCT
admet-130	259	13	a.	a.	NOUN
admet-130	259	14	vivanti	vivanti	PROPN
admet-130	259	15	,	,	PUNCT
admet-130	259	16	t.	t.	PROPN
admet-130	259	17	feccia	feccia	PROPN
admet-130	259	18	,	,	PUNCT
admet-130	259	19	d.	d.	PROPN
admet-130	259	20	lauro	lauro	PROPN
admet-130	259	21	,	,	PUNCT
admet-130	259	22	a.	a.	NOUN
admet-130	259	23	fumikazu	fumikazu	PROPN
admet-130	259	24	,	,	PUNCT
admet-130	259	25	r.	r.	PROPN
admet-130	259	26	lauro	lauro	PROPN
admet-130	259	27	,	,	PUNCT
admet-130	259	28	m.	m.	NOUN
admet-130	259	29	federici	federici	NOUN
admet-130	259	30	,	,	PUNCT
admet-130	259	31	diabetes	diabete	VERB
admet-130	259	32	55	55	NUM
admet-130	259	33	(	(	PUNCT
admet-130	259	34	2006	2006	NUM
admet-130	259	35	)	)	PUNCT
admet-130	259	36	2231	2231	NUM
admet-130	259	37	-	-	SYM
admet-130	259	38	2237	2237	NUM
admet-130	259	39	.	.	PUNCT
admet-130	260	1	[	[	X
admet-130	260	2	60	60	NUM
admet-130	260	3	]	]	X
admet-130	260	4	f.	f.	PROPN
admet-130	260	5	pomero	pomero	PROPN
admet-130	260	6	,	,	PUNCT
admet-130	260	7	a.	a.	PROPN
admet-130	260	8	min	min	PROPN
admet-130	260	9	molinar	molinar	PROPN
admet-130	260	10	,	,	PUNCT
admet-130	260	11	m.	m.	NOUN
admet-130	260	12	la	la	PROPN
admet-130	260	13	selva	selva	PROPN
admet-130	260	14	,	,	PUNCT
admet-130	260	15	a	a	DET
admet-130	260	16	allione	allione	ADJ
admet-130	260	17	,	,	PUNCT
admet-130	260	18	g.m	g.m	PROPN
admet-130	260	19	.	.	PROPN
admet-130	260	20	molinatti	molinatti	PROPN
admet-130	260	21	,	,	PUNCT
admet-130	260	22	m.	m.	NOUN
admet-130	260	23	porta	porta	PROPN
admet-130	260	24	,	,	PUNCT
admet-130	260	25	acta	acta	PROPN
admet-130	260	26	diabetol	diabetol	ADJ
admet-130	260	27	.	.	PUNCT
admet-130	261	1	38	38	NUM
admet-130	261	2	(	(	PUNCT
admet-130	261	3	2001	2001	NUM
admet-130	261	4	)	)	PUNCT
admet-130	261	5	135	135	NUM
admet-130	261	6	-	-	SYM
admet-130	261	7	138	138	NUM
admet-130	261	8	.	.	PUNCT
admet-130	262	1	[	[	X
admet-130	262	2	61	61	NUM
admet-130	262	3	]	]	X
admet-130	262	4	e.	e.	PROPN
admet-130	262	5	beltramo	beltramo	PROPN
admet-130	262	6	,	,	PUNCT
admet-130	262	7	e.	e.	PROPN
admet-130	262	8	berrone	berrone	PROPN
admet-130	262	9	,	,	PUNCT
admet-130	262	10	s.	s.	PROPN
admet-130	262	11	buttiglieri	buttiglieri	PROPN
admet-130	262	12	,	,	PUNCT
admet-130	262	13	m.	m.	NOUN
admet-130	262	14	porta	porta	NOUN
admet-130	262	15	,	,	PUNCT
admet-130	262	16	diabetes	diabete	VERB
admet-130	262	17	metab	metab	NOUN
admet-130	262	18	.	.	PUNCT
admet-130	263	1	res	re	NOUN
admet-130	263	2	.	.	PUNCT
admet-130	264	1	rev	rev	PROPN
admet-130	264	2	.	.	PROPN
admet-130	264	3	20	20	NUM
admet-130	264	4	(	(	PUNCT
admet-130	264	5	2004	2004	NUM
admet-130	264	6	)	)	PUNCT
admet-130	264	7	330	330	NUM
admet-130	264	8	-	-	SYM
admet-130	264	9	336	336	NUM
admet-130	264	10	.	.	PUNCT
admet-130	265	1	[	[	X
admet-130	265	2	62	62	NUM
admet-130	265	3	]	]	X
admet-130	265	4	s.h	s.h	PROPN
admet-130	265	5	.	.	PROPN
admet-130	266	1	oh	oh	INTJ
admet-130	266	2	r.p	r.p	PROPN
admet-130	266	3	.	.	PROPN
admet-130	266	4	witek	witek	PROPN
admet-130	266	5	,	,	PUNCT
admet-130	266	6	s.h	s.h	PROPN
admet-130	266	7	.	.	PROPN
admet-130	266	8	bae	bae	PROPN
admet-130	266	9	,	,	PUNCT
admet-130	266	10	h.a	h.a	PROPN
admet-130	266	11	.	.	PROPN
admet-130	266	12	darwiche	darwiche	PROPN
admet-130	266	13	,	,	PUNCT
admet-130	266	14	y.	y.	PROPN
admet-130	266	15	jung	jung	PROPN
admet-130	266	16	,	,	PUNCT
admet-130	266	17	l.	l.	PROPN
admet-130	266	18	pi	pi	PROPN
admet-130	266	19	,	,	PUNCT
admet-130	266	20	a.	a.	PROPN
admet-130	266	21	brown	brown	PROPN
admet-130	266	22	,	,	PUNCT
admet-130	266	23	b.e	b.e	PROPN
admet-130	266	24	.	.	PROPN
admet-130	266	25	petersen	petersen	PROPN
admet-130	266	26	,	,	PUNCT
admet-130	266	27	stem	stem	NOUN
admet-130	266	28	cells	cell	NOUN
admet-130	266	29	dev	dev	PROPN
admet-130	266	30	.	.	PROPN
admet-130	267	1	18	18	NUM
admet-130	267	2	(	(	PUNCT
admet-130	267	3	2009	2009	NUM
admet-130	267	4	)	)	PUNCT
admet-130	267	5	37	37	NUM
admet-130	267	6	-	-	SYM
admet-130	267	7	46	46	NUM
admet-130	267	8	.	.	PUNCT
admet-130	268	1	[	[	X
admet-130	268	2	63	63	NUM
admet-130	268	3	]	]	PUNCT
admet-130	268	4	t.	t.	PROPN
admet-130	268	5	hanawa	hanawa	PROPN
admet-130	268	6	,	,	PUNCT
admet-130	268	7	a.	a.	PROPN
admet-130	268	8	watanabe	watanabe	PROPN
admet-130	268	9	,	,	PUNCT
admet-130	268	10	t.	t.	PROPN
admet-130	268	11	tsuchiya	tsuchiya	PROPN
admet-130	268	12	,	,	PUNCT
admet-130	268	13	r.	r.	PROPN
admet-130	268	14	ilkoma	ilkoma	PROPN
admet-130	268	15	,	,	PUNCT
admet-130	268	16	m.	m.	NOUN
admet-130	268	17	hidaka	hidaka	PROPN
admet-130	268	18	,	,	PUNCT
admet-130	268	19	m.	m.	NOUN
admet-130	268	20	sugihara	sugihara	NOUN
admet-130	268	21	,	,	PUNCT
admet-130	268	22	chem	chem	NOUN
admet-130	268	23	.	.	PUNCT
admet-130	269	1	pharm	pharm	NOUN
admet-130	269	2	.	.	PUNCT
admet-130	270	1	bull	bull	NOUN
admet-130	270	2	.	.	PUNCT
admet-130	271	1	(	(	PUNCT
admet-130	271	2	tokyo	tokyo	PROPN
admet-130	271	3	)	)	PUNCT
admet-130	271	4	43	43	NUM
admet-130	271	5	(	(	PUNCT
admet-130	271	6	1995	1995	NUM
admet-130	271	7	)	)	PUNCT
admet-130	271	8	872	872	NUM
admet-130	271	9	-	-	SYM
admet-130	271	10	876	876	NUM
admet-130	271	11	.	.	PUNCT
admet-130	272	1	[	[	X
admet-130	272	2	64	64	NUM
admet-130	272	3	]	]	PUNCT
admet-130	272	4	s.	s.	PROPN
admet-130	272	5	simeonov	simeonov	PROPN
admet-130	272	6	,	,	PUNCT
admet-130	272	7	m.	m.	NOUN
admet-130	272	8	pavlova	pavlova	PROPN
admet-130	272	9	,	,	PUNCT
admet-130	272	10	m.	m.	NOUN
admet-130	272	11	mitkov	mitkov	PROPN
admet-130	272	12	,	,	PUNCT
admet-130	272	13	l.	l.	PROPN
admet-130	272	14	mincheva	mincheva	PROPN
admet-130	272	15	,	,	PUNCT
admet-130	272	16	d.	d.	PROPN
admet-130	272	17	troev	troev	PROPN
admet-130	272	18	,	,	PUNCT
admet-130	272	19	folia	folia	PROPN
admet-130	272	20	med	med	PROPN
admet-130	272	21	.	.	PUNCT
admet-130	273	1	(	(	PUNCT
admet-130	273	2	plovdiv	plovdiv	NOUN
admet-130	273	3	)	)	PUNCT
admet-130	273	4	39	39	NUM
admet-130	273	5	(	(	PUNCT
admet-130	273	6	1997	1997	NUM
admet-130	273	7	)	)	PUNCT
admet-130	273	8	5	5	NUM
admet-130	273	9	-	-	SYM
admet-130	273	10	10	10	NUM
admet-130	273	11	.	.	PUNCT
admet-130	274	1	[	[	X
admet-130	274	2	65	65	NUM
admet-130	274	3	]	]	X
admet-130	274	4	s.g	s.g	PROPN
admet-130	274	5	.	.	PROPN
admet-130	274	6	carter	carter	PROPN
admet-130	274	7	,	,	PUNCT
admet-130	274	8	z.	z.	PROPN
admet-130	274	9	zhu	zhu	PROPN
admet-130	274	10	,	,	PUNCT
admet-130	274	11	g.	g.	PROPN
admet-130	274	12	varadi	varadi	PROPN
admet-130	274	13	,	,	PUNCT
admet-130	274	14	a.	a.	NOUN
admet-130	274	15	veves	veve	NOUN
admet-130	274	16	,	,	PUNCT
admet-130	274	17	j.e	j.e	PROPN
admet-130	274	18	.	.	PROPN
admet-130	274	19	riviere	riviere	PROPN
admet-130	274	20	,	,	PUNCT
admet-130	274	21	j.	j.	PROPN
admet-130	274	22	pharmaceut	pharmaceut	PROPN
admet-130	274	23	.	.	PUNCT
admet-130	275	1	sci	sci	PROPN
admet-130	275	2	.	.	PROPN
admet-130	276	1	102	102	NUM
admet-130	276	2	(	(	PUNCT
admet-130	276	3	2013	2013	NUM
admet-130	276	4	)	)	PUNCT
admet-130	276	5	4072	4072	NUM
admet-130	276	6	-	-	SYM
admet-130	276	7	4078	4078	NUM
admet-130	276	8	.	.	PUNCT
admet-130	277	1	[	[	X
admet-130	277	2	66	66	NUM
admet-130	277	3	]	]	PUNCT
admet-130	277	4	c.	c.	PROPN
admet-130	277	5	herve	herve	PROPN
admet-130	277	6	,	,	PUNCT
admet-130	277	7	p.	p.	PROPN
admet-130	277	8	beyne	beyne	PROPN
admet-130	277	9	,	,	PUNCT
admet-130	277	10	e.	e.	PROPN
admet-130	277	11	delacoux	delacoux	PROPN
admet-130	277	12	,	,	PUNCT
admet-130	277	13	j.	j.	PROPN
admet-130	277	14	chromatogr	chromatogr	PROPN
admet-130	277	15	.	.	PUNCT
admet-130	278	1	b	b	X
admet-130	278	2	,	,	PUNCT
admet-130	278	3	653	653	NUM
admet-130	278	4	(	(	PUNCT
admet-130	278	5	1994	1994	NUM
admet-130	278	6	)	)	PUNCT
admet-130	278	7	217	217	NUM
admet-130	278	8	-	-	SYM
admet-130	278	9	220	220	NUM
admet-130	278	10	.	.	PUNCT
admet-130	279	1	[	[	X
admet-130	279	2	67	67	NUM
admet-130	279	3	]	]	PUNCT
admet-130	279	4	m.	m.	NOUN
admet-130	279	5	ziems	ziem	NOUN
admet-130	279	6	,	,	PUNCT
admet-130	279	7	m.	m.	NOUN
admet-130	279	8	netzel	netzel	PROPN
admet-130	279	9	,	,	PUNCT
admet-130	279	10	s.	s.	PROPN
admet-130	279	11	peter	peter	PROPN
admet-130	279	12	,	,	PUNCT
admet-130	279	13	i.	i.	PROPN
admet-130	279	14	bitsch	bitsch	PROPN
admet-130	279	15	,	,	PUNCT
admet-130	279	16	vitamine	vitamine	NOUN
admet-130	279	17	und	und	PROPN
admet-130	279	18	zusatzstoffe	zusatzstoffe	PROPN
admet-130	279	19	in	in	ADP
admet-130	279	20	der	der	PROPN
admet-130	279	21	ernahrung	ernahrung	PROPN
admet-130	279	22	von	von	PROPN
admet-130	279	23	mensch	mensch	PROPN
admet-130	279	24	und	und	PROPN
admet-130	279	25	tier	tier	NOUN
admet-130	279	26	,	,	PUNCT
admet-130	279	27	5	5	NUM
admet-130	279	28	.	.	PUNCT
admet-130	279	29	symposium	symposium	NOUN
admet-130	279	30	jena	jena	PROPN
admet-130	279	31	(	(	PUNCT
admet-130	279	32	1995	1995	NUM
admet-130	279	33	)	)	PUNCT
admet-130	279	34	320	320	NUM
admet-130	279	35	-	-	SYM
admet-130	279	36	323	323	NUM
admet-130	280	1	[	[	X
admet-130	280	2	68	68	NUM
admet-130	280	3	]	]	PUNCT
admet-130	280	4	p.l.m	p.l.m	NOUN
admet-130	280	5	.	.	PUNCT
admet-130	281	1	lynch	lynch	PROPN
admet-130	281	2	,	,	PUNCT
admet-130	281	3	e.r	e.r	PROPN
admet-130	281	4	.	.	PROPN
admet-130	281	5	trimble	trimble	PROPN
admet-130	281	6	,	,	PUNCT
admet-130	281	7	i.s	i.s	PROPN
admet-130	281	8	.	.	PROPN
admet-130	281	9	young	young	PROPN
admet-130	281	10	,	,	PUNCT
admet-130	281	11	j.	j.	PROPN
admet-130	281	12	chromatogr	chromatogr	PROPN
admet-130	281	13	.	.	PUNCT
admet-130	282	1	b	b	X
admet-130	282	2	,	,	PUNCT
admet-130	282	3	701	701	NUM
admet-130	282	4	(	(	PUNCT
admet-130	282	5	1997	1997	NUM
admet-130	282	6	)	)	PUNCT
admet-130	282	7	120	120	NUM
admet-130	282	8	-	-	SYM
admet-130	282	9	123	123	NUM
admet-130	282	10	.	.	PUNCT
admet-130	283	1	[	[	X
admet-130	283	2	69	69	NUM
admet-130	283	3	]	]	X
admet-130	283	4	d.	d.	PROPN
admet-130	283	5	talwar	talwar	PROPN
admet-130	283	6	,	,	PUNCT
admet-130	283	7	h.	h.	PROPN
admet-130	283	8	davidson	davidson	PROPN
admet-130	283	9	,	,	PUNCT
admet-130	283	10	j.	j.	PROPN
admet-130	283	11	cooney	cooney	PROPN
admet-130	283	12	,	,	PUNCT
admet-130	283	13	d.st	d.st	PROPN
admet-130	283	14	.	.	PUNCT
admet-130	284	1	jo’reilly	jo’reilly	ADV
admet-130	284	2	,	,	PUNCT
admet-130	284	3	clinical	clinical	ADJ
admet-130	284	4	chemistry	chemistry	NOUN
admet-130	284	5	46	46	NUM
admet-130	284	6	(	(	PUNCT
admet-130	284	7	2000	2000	NUM
admet-130	284	8	)	)	PUNCT
admet-130	284	9	704	704	NUM
admet-130	284	10	-	-	SYM
admet-130	284	11	710	710	NUM
admet-130	284	12	.	.	PUNCT
admet-130	285	1	[	[	X
admet-130	285	2	70	70	NUM
admet-130	285	3	]	]	X
admet-130	285	4	b.a.j	b.a.j	PROPN
admet-130	285	5	.	.	PUNCT
admet-130	286	1	van	van	PROPN
admet-130	286	2	landeghem	landeghem	PROPN
admet-130	286	3	,	,	PUNCT
admet-130	286	4	j.	j.	PROPN
admet-130	286	5	puts	puts	PROPN
admet-130	286	6	,	,	PUNCT
admet-130	286	7	h.a	h.a	PROPN
admet-130	286	8	.	.	PROPN
admet-130	286	9	claessens	claessens	PROPN
admet-130	286	10	,	,	PUNCT
admet-130	286	11	j.	j.	PROPN
admet-130	286	12	chromatogr	chromatogr	PROPN
admet-130	286	13	.	.	PUNCT
admet-130	287	1	b	b	X
admet-130	287	2	,	,	PUNCT
admet-130	287	3	822	822	NUM
admet-130	287	4	(	(	PUNCT
admet-130	287	5	2005	2005	NUM
admet-130	287	6	)	)	PUNCT
admet-130	287	7	316	316	NUM
admet-130	287	8	-	-	SYM
admet-130	287	9	321	321	NUM
admet-130	287	10	.	.	PUNCT
admet-130	288	1	[	[	X
admet-130	288	2	71	71	NUM
admet-130	288	3	]	]	X
admet-130	288	4	d.	d.	PROPN
admet-130	288	5	loew	loew	PROPN
admet-130	288	6	,	,	PUNCT
admet-130	288	7	int	int	PROPN
admet-130	288	8	.	.	PUNCT
admet-130	289	1	j.	j.	PROPN
admet-130	289	2	clin	clin	PROPN
admet-130	289	3	.	.	PUNCT
admet-130	290	1	pharmacol	pharmacol	PROPN
admet-130	290	2	.	.	PUNCT
admet-130	291	1	ther	ther	PROPN
admet-130	291	2	.	.	PUNCT
admet-130	292	1	34	34	NUM
admet-130	292	2	(	(	PUNCT
admet-130	292	3	1996	1996	NUM
admet-130	292	4	)	)	PUNCT
admet-130	292	5	47	47	NUM
admet-130	292	6	-	-	SYM
admet-130	292	7	50	50	NUM
admet-130	292	8	.	.	PUNCT
admet-130	293	1	[	[	X
admet-130	293	2	72	72	NUM
admet-130	293	3	]	]	X
admet-130	293	4	a.	a.	NOUN
admet-130	293	5	greb	greb	PROPN
admet-130	293	6	,	,	PUNCT
admet-130	293	7	r.	r.	PROPN
admet-130	293	8	bitsch	bitsch	PROPN
admet-130	293	9	,	,	PUNCT
admet-130	293	10	int	int	PROPN
admet-130	293	11	.	.	PUNCT
admet-130	294	1	j.	j.	PROPN
admet-130	294	2	clin	clin	PROPN
admet-130	294	3	.	.	PUNCT
admet-130	295	1	pharmacol	pharmacol	PROPN
admet-130	295	2	.	.	PUNCT
admet-130	296	1	36	36	NUM
admet-130	296	2	(	(	PUNCT
admet-130	296	3	1998	1998	NUM
admet-130	296	4	)	)	PUNCT
admet-130	296	5	216	216	NUM
admet-130	296	6	-	-	SYM
admet-130	296	7	221	221	NUM
admet-130	296	8	.	.	PUNCT
admet-130	297	1	[	[	X
admet-130	297	2	73	73	NUM
admet-130	297	3	]	]	PUNCT
admet-130	297	4	t.	t.	PROPN
admet-130	297	5	frank	frank	PROPN
admet-130	297	6	,	,	PUNCT
admet-130	297	7	r.	r.	PROPN
admet-130	297	8	bitsch	bitsch	PROPN
admet-130	297	9	,	,	PUNCT
admet-130	297	10	j	j	PROPN
admet-130	297	11	maiwald	maiwald	NOUN
admet-130	297	12	,	,	PUNCT
admet-130	297	13	g.	g.	PROPN
admet-130	297	14	stein	stein	PROPN
admet-130	297	15	,	,	PUNCT
admet-130	297	16	eur	eur	PROPN
admet-130	297	17	.	.	PUNCT
admet-130	298	1	j.	j.	PROPN
admet-130	298	2	clin	clin	PROPN
admet-130	298	3	.	.	PUNCT
admet-130	299	1	pharmacol	pharmacol	PROPN
admet-130	299	2	.	.	PUNCT
admet-130	300	1	56	56	NUM
admet-130	300	2	(	(	PUNCT
admet-130	300	3	2000	2000	NUM
admet-130	300	4	)	)	PUNCT
admet-130	300	5	251	251	NUM
admet-130	300	6	-	-	SYM
admet-130	300	7	257	257	NUM
admet-130	300	8	.	.	PUNCT
admet-130	301	1	[	[	X
admet-130	301	2	74	74	NUM
admet-130	301	3	]	]	PUNCT
admet-130	301	4	r.	r.	PROPN
admet-130	301	5	bitsch	bitsch	PROPN
admet-130	301	6	,	,	PUNCT
admet-130	301	7	m.	m.	NOUN
admet-130	301	8	wolf	wolf	PROPN
admet-130	301	9	,	,	PUNCT
admet-130	301	10	j.	j.	PROPN
admet-130	301	11	moller	moller	PROPN
admet-130	301	12	,	,	PUNCT
admet-130	301	13	l.	l.	PROPN
admet-130	301	14	heuzeroth	heuzeroth	PROPN
admet-130	301	15	,	,	PUNCT
admet-130	301	16	d.	d.	PROPN
admet-130	301	17	gruneklee	gruneklee	PROPN
admet-130	301	18	,	,	PUNCT
admet-130	301	19	ann	ann	PROPN
admet-130	301	20	.	.	PUNCT
admet-130	302	1	nutr	nutr	PROPN
admet-130	302	2	.	.	PROPN
admet-130	303	1	metab	metab	PROPN
admet-130	303	2	.	.	PUNCT
admet-130	304	1	35	35	NUM
admet-130	304	2	(	(	PUNCT
admet-130	304	3	1991	1991	NUM
admet-130	304	4	)	)	PUNCT
admet-130	304	5	292	292	NUM
admet-130	304	6	-	-	SYM
admet-130	304	7	296	296	NUM
admet-130	304	8	.	.	PUNCT
admet-130	305	1	©	©	PROPN
admet-130	305	2	2014	2014	NUM
admet-130	305	3	by	by	ADP
admet-130	305	4	the	the	DET
admet-130	305	5	authors	author	NOUN
admet-130	305	6	;	;	PUNCT
admet-130	305	7	licensee	licensee	PROPN
admet-130	305	8	iapc	iapc	PROPN
admet-130	305	9	,	,	PUNCT
admet-130	305	10	zagreb	zagreb	PROPN
admet-130	305	11	,	,	PUNCT
admet-130	305	12	croatia	croatia	PROPN
admet-130	305	13	.	.	PUNCT
admet-130	306	1	this	this	DET
admet-130	306	2	article	article	NOUN
admet-130	306	3	is	be	AUX
admet-130	306	4	an	an	DET
admet-130	306	5	open	open	ADJ
admet-130	306	6	-	-	PUNCT
admet-130	306	7	access	access	NOUN
admet-130	306	8	article	article	NOUN
admet-130	306	9	distributed	distribute	VERB
admet-130	306	10	under	under	ADP
admet-130	306	11	the	the	DET
admet-130	306	12	terms	term	NOUN
admet-130	306	13	and	and	CCONJ
admet-130	306	14	conditions	condition	NOUN
admet-130	306	15	of	of	ADP
admet-130	306	16	the	the	DET
admet-130	306	17	creative	creative	ADJ
admet-130	306	18	commons	common	NOUN
admet-130	306	19	attribution	attribution	NOUN
admet-130	306	20	license	license	NOUN
admet-130	306	21	(	(	PUNCT
admet-130	306	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-130	306	23	)	)	PUNCT