id	sid	tid	token	lemma	pos
admet-1317	1	1	levothyroxine	levothyroxine	PROPN
admet-1317	1	2	sodium	sodium	NOUN
admet-1317	1	3	loaded	load	VERB
admet-1317	1	4	dissolving	dissolving	NOUN
admet-1317	1	5	microneedle	microneedle	NOUN
admet-1317	1	6	arrays	array	VERB
admet-1317	1	7	for	for	ADP
admet-1317	1	8	transdermal	transdermal	ADJ
admet-1317	1	9	delivery	delivery	NOUN
admet-1317	1	10	doi	doi	NOUN
admet-1317	1	11	:	:	PUNCT
admet-1317	1	12	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	NUM
admet-1317	1	13	213	213	NUM
admet-1317	1	14	admet	admet	X
admet-1317	1	15	&	&	CCONJ
admet-1317	1	16	dmpk	dmpk	PROPN
admet-1317	1	17	10(3	10(3	NUM
admet-1317	1	18	)	)	PUNCT
admet-1317	1	19	(	(	PUNCT
admet-1317	1	20	2022	2022	NUM
admet-1317	1	21	)	)	PUNCT
admet-1317	1	22	213	213	NUM
admet-1317	1	23	-	-	SYM
admet-1317	1	24	230	230	NUM
admet-1317	1	25	;	;	PUNCT
admet-1317	1	26	doi	doi	NOUN
admet-1317	1	27	:	:	PUNCT
admet-1317	1	28	https://doi.org/10.5599/admet.1317	https://doi.org/10.5599/admet.1317	NOUN
admet-1317	1	29	open	open	ADJ
admet-1317	1	30	access	access	NOUN
admet-1317	1	31	:	:	PUNCT
admet-1317	1	32	issn	issn	PROPN
admet-1317	1	33	:	:	PUNCT
admet-1317	1	34	1848	1848	NUM
admet-1317	1	35	-	-	SYM
admet-1317	1	36	7718	7718	NUM
admet-1317	1	37	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-1317	1	38	original	original	ADJ
admet-1317	1	39	scientific	scientific	ADJ
admet-1317	1	40	paper	paper	NOUN
admet-1317	1	41	levothyroxine	levothyroxine	NOUN
admet-1317	1	42	sodium	sodium	NOUN
admet-1317	1	43	loaded	load	VERB
admet-1317	1	44	dissolving	dissolving	NOUN
admet-1317	1	45	microneedle	microneedle	NOUN
admet-1317	1	46	arrays	array	VERB
admet-1317	1	47	for	for	ADP
admet-1317	1	48	transdermal	transdermal	ADJ
admet-1317	1	49	delivery	delivery	NOUN
admet-1317	1	50	riyam	riyam	PROPN
admet-1317	1	51	f.	f.	PROPN
admet-1317	1	52	ghazi	ghazi	PROPN
admet-1317	1	53	,	,	PUNCT
admet-1317	1	54	mohammed	mohammed	PROPN
admet-1317	1	55	h.	h.	PROPN
admet-1317	1	56	al	al	PROPN
admet-1317	1	57	-	-	PUNCT
admet-1317	1	58	mayahy	mayahy	PROPN
admet-1317	1	59	*	*	PROPN
admet-1317	1	60	department	department	PROPN
admet-1317	1	61	of	of	ADP
admet-1317	1	62	pharmaceutics	pharmaceutic	NOUN
admet-1317	1	63	,	,	PUNCT
admet-1317	1	64	college	college	NOUN
admet-1317	1	65	of	of	ADP
admet-1317	1	66	pharmacy	pharmacy	NOUN
admet-1317	1	67	,	,	PUNCT
admet-1317	1	68	mustansiriyah	mustansiriyah	NOUN
admet-1317	1	69	university	university	NOUN
admet-1317	1	70	,	,	PUNCT
admet-1317	1	71	baghdad	baghdad	PROPN
admet-1317	1	72	-	-	PUNCT
admet-1317	1	73	iraq	iraq	PROPN
admet-1317	1	74	*	*	PUNCT
admet-1317	1	75	corresponding	correspond	VERB
admet-1317	1	76	author	author	NOUN
admet-1317	1	77	:	:	PUNCT
admet-1317	1	78	e	e	NOUN
admet-1317	1	79	-	-	NOUN
admet-1317	1	80	mail	mail	NOUN
admet-1317	1	81	:	:	PUNCT
admet-1317	1	82	mohammedhussain@uomustansiriyah.edu.iq	mohammedhussain@uomustansiriyah.edu.iq	NOUN
admet-1317	1	83	received	receive	VERB
admet-1317	1	84	:	:	PUNCT
admet-1317	1	85	march	march	PROPN
admet-1317	1	86	06	06	NUM
admet-1317	1	87	,	,	PUNCT
admet-1317	1	88	2022	2022	NUM
admet-1317	1	89	;	;	PUNCT
admet-1317	1	90	revised	revise	VERB
admet-1317	1	91	:	:	PUNCT
admet-1317	1	92	april	april	PROPN
admet-1317	1	93	26	26	NUM
admet-1317	1	94	,	,	PUNCT
admet-1317	1	95	2022	2022	NUM
admet-1317	1	96	;	;	PUNCT
admet-1317	1	97	available	available	ADJ
admet-1317	1	98	online	online	ADV
admet-1317	1	99	:	:	PUNCT
admet-1317	1	100	may	may	AUX
admet-1317	1	101	21	21	NUM
admet-1317	1	102	,	,	PUNCT
admet-1317	1	103	2022	2022	NUM
admet-1317	1	104	abstract	abstract	ADJ
admet-1317	1	105	levothyroxine	levothyroxine	NOUN
admet-1317	1	106	(	(	PUNCT
admet-1317	1	107	lt-4	lt-4	NOUN
admet-1317	1	108	)	)	PUNCT
admet-1317	1	109	sodium	sodium	NOUN
admet-1317	1	110	has	have	AUX
admet-1317	1	111	shown	show	VERB
admet-1317	1	112	variable	variable	ADJ
admet-1317	1	113	bioavailability	bioavailability	NOUN
admet-1317	1	114	following	follow	VERB
admet-1317	1	115	oral	oral	ADJ
admet-1317	1	116	administration	administration	NOUN
admet-1317	1	117	.	.	PUNCT
admet-1317	2	1	this	this	PRON
admet-1317	2	2	can	can	AUX
admet-1317	2	3	be	be	AUX
admet-1317	2	4	assigned	assign	VERB
admet-1317	2	5	to	to	ADP
admet-1317	2	6	the	the	DET
admet-1317	2	7	significant	significant	ADJ
admet-1317	2	8	influence	influence	NOUN
admet-1317	2	9	of	of	ADP
admet-1317	2	10	gastrointestinal	gastrointestinal	ADJ
admet-1317	2	11	conditions	condition	NOUN
admet-1317	2	12	,	,	PUNCT
admet-1317	2	13	food	food	NOUN
admet-1317	2	14	and	and	CCONJ
admet-1317	2	15	drugs	drug	NOUN
admet-1317	2	16	administered	administer	VERB
admet-1317	2	17	concomitantly	concomitantly	ADV
admet-1317	2	18	on	on	ADP
admet-1317	2	19	the	the	DET
admet-1317	2	20	rate	rate	NOUN
admet-1317	2	21	and	and	CCONJ
admet-1317	2	22	extent	extent	NOUN
admet-1317	2	23	of	of	ADP
admet-1317	2	24	absorption	absorption	NOUN
admet-1317	2	25	from	from	ADP
admet-1317	2	26	the	the	DET
admet-1317	2	27	gastrointestinal	gastrointestinal	ADJ
admet-1317	2	28	tract	tract	NOUN
admet-1317	2	29	.	.	PUNCT
admet-1317	3	1	thus	thus	ADV
admet-1317	3	2	,	,	PUNCT
admet-1317	3	3	the	the	DET
admet-1317	3	4	aim	aim	NOUN
admet-1317	3	5	of	of	ADP
admet-1317	3	6	this	this	DET
admet-1317	3	7	research	research	NOUN
admet-1317	3	8	study	study	NOUN
admet-1317	3	9	was	be	AUX
admet-1317	3	10	to	to	PART
admet-1317	3	11	establish	establish	VERB
admet-1317	3	12	an	an	DET
admet-1317	3	13	efficient	efficient	ADJ
admet-1317	3	14	transdermal	transdermal	ADJ
admet-1317	3	15	delivery	delivery	NOUN
admet-1317	3	16	system	system	NOUN
admet-1317	3	17	of	of	ADP
admet-1317	3	18	lt-4	lt-4	NOUN
admet-1317	3	19	sodium	sodium	NOUN
admet-1317	3	20	via	via	ADP
admet-1317	3	21	the	the	DET
admet-1317	3	22	application	application	NOUN
admet-1317	3	23	of	of	ADP
admet-1317	3	24	hyaluronic	hyaluronic	ADJ
admet-1317	3	25	acid	acid	NOUN
admet-1317	3	26	dissolving	dissolve	VERB
admet-1317	3	27	microneedles	microneedle	NOUN
admet-1317	3	28	.	.	PUNCT
admet-1317	4	1	microneedles	microneedle	NOUN
admet-1317	4	2	-	-	PUNCT
admet-1317	4	3	based	base	VERB
admet-1317	4	4	drug	drug	NOUN
admet-1317	4	5	delivery	delivery	NOUN
admet-1317	4	6	system	system	NOUN
admet-1317	4	7	consists	consist	VERB
admet-1317	4	8	of	of	ADP
admet-1317	4	9	sharp	sharp	ADJ
admet-1317	4	10	-	-	PUNCT
admet-1317	4	11	tip	tip	NOUN
admet-1317	4	12	needles	needle	NOUN
admet-1317	4	13	that	that	PRON
admet-1317	4	14	puncture	puncture	VERB
admet-1317	4	15	the	the	DET
admet-1317	4	16	top	top	ADJ
admet-1317	4	17	layers	layer	NOUN
admet-1317	4	18	of	of	ADP
admet-1317	4	19	the	the	DET
admet-1317	4	20	skin	skin	NOUN
admet-1317	4	21	in	in	ADP
admet-1317	4	22	a	a	DET
admet-1317	4	23	minimally	minimally	ADV
admet-1317	4	24	invasive	invasive	ADJ
admet-1317	4	25	manner	manner	NOUN
admet-1317	4	26	to	to	PART
admet-1317	4	27	create	create	VERB
admet-1317	4	28	physical	physical	ADJ
admet-1317	4	29	channels	channel	NOUN
admet-1317	4	30	through	through	ADP
admet-1317	4	31	which	which	PRON
admet-1317	4	32	therapeutic	therapeutic	ADJ
admet-1317	4	33	molecules	molecule	NOUN
admet-1317	4	34	can	can	AUX
admet-1317	4	35	easily	easily	ADV
admet-1317	4	36	diffuse	diffuse	VERB
admet-1317	4	37	into	into	ADP
admet-1317	4	38	/	/	SYM
admet-1317	4	39	across	across	ADP
admet-1317	4	40	the	the	DET
admet-1317	4	41	skin	skin	NOUN
admet-1317	4	42	.	.	PUNCT
admet-1317	5	1	hyaluronic	hyaluronic	ADJ
admet-1317	5	2	acid	acid	NOUN
admet-1317	5	3	polymer	polymer	NOUN
admet-1317	5	4	at	at	ADP
admet-1317	5	5	different	different	ADJ
admet-1317	5	6	ratios	ratio	NOUN
admet-1317	5	7	(	(	PUNCT
admet-1317	5	8	5	5	NUM
admet-1317	5	9	-	-	SYM
admet-1317	5	10	60	60	NUM
admet-1317	5	11	%	%	NOUN
admet-1317	5	12	)	)	PUNCT
admet-1317	5	13	was	be	AUX
admet-1317	5	14	used	use	VERB
admet-1317	5	15	to	to	PART
admet-1317	5	16	prepare	prepare	VERB
admet-1317	5	17	microneedle	microneedle	NOUN
admet-1317	5	18	arrays	array	NOUN
admet-1317	5	19	(	(	PUNCT
admet-1317	5	20	100	100	NUM
admet-1317	5	21	needles	needle	NOUN
admet-1317	5	22	per	per	ADP
admet-1317	5	23	array	array	NOUN
admet-1317	5	24	)	)	PUNCT
admet-1317	5	25	using	use	VERB
admet-1317	5	26	a	a	DET
admet-1317	5	27	micromoulding	micromoulde	VERB
admet-1317	5	28	technique	technique	NOUN
admet-1317	5	29	.	.	PUNCT
admet-1317	6	1	characterisation	characterisation	NOUN
admet-1317	6	2	tests	test	NOUN
admet-1317	6	3	were	be	AUX
admet-1317	6	4	carried	carry	VERB
admet-1317	6	5	out	out	ADP
admet-1317	6	6	to	to	PART
admet-1317	6	7	select	select	VERB
admet-1317	6	8	the	the	DET
admet-1317	6	9	optimum	optimum	ADJ
admet-1317	6	10	formulation	formulation	NOUN
admet-1317	6	11	.	.	PUNCT
admet-1317	7	1	f11	f11	PROPN
admet-1317	7	2	formula	formula	NOUN
admet-1317	7	3	containing	contain	VERB
admet-1317	7	4	50	50	NUM
admet-1317	7	5	%	%	NOUN
admet-1317	7	6	w	w	NOUN
admet-1317	7	7	/	/	SYM
admet-1317	7	8	v	v	NOUN
admet-1317	7	9	hyaluronic	hyaluronic	ADJ
admet-1317	7	10	acid	acid	NOUN
admet-1317	7	11	and	and	CCONJ
admet-1317	7	12	1	1	NUM
admet-1317	7	13	%	%	NOUN
admet-1317	7	14	v	v	ADP
admet-1317	7	15	/	/	SYM
admet-1317	7	16	v	v	NOUN
admet-1317	7	17	tween	tween	NOUN
admet-1317	7	18	80	80	NUM
admet-1317	7	19	formula	formula	NOUN
admet-1317	7	20	showed	show	VERB
admet-1317	7	21	an	an	DET
admet-1317	7	22	appropriate	appropriate	ADJ
admet-1317	7	23	needle	needle	NOUN
admet-1317	7	24	shape	shape	NOUN
admet-1317	7	25	with	with	ADP
admet-1317	7	26	dimensions	dimension	NOUN
admet-1317	7	27	of	of	ADP
admet-1317	7	28	432	432	NUM
admet-1317	7	29	±	±	NUM
admet-1317	7	30	6.4	6.4	NUM
admet-1317	7	31	μm	μm	NOUN
admet-1317	7	32	in	in	ADP
admet-1317	7	33	height	height	NOUN
admet-1317	7	34	and	and	CCONJ
admet-1317	7	35	a	a	DET
admet-1317	7	36	tip	tip	NOUN
admet-1317	7	37	diameter	diameter	NOUN
admet-1317	7	38	of	of	ADP
admet-1317	7	39	9.8	9.8	NUM
admet-1317	7	40	±	±	NUM
admet-1317	7	41	1.3	1.3	NUM
admet-1317	7	42	μm	μm	NOUN
admet-1317	7	43	.	.	PUNCT
admet-1317	8	1	the	the	DET
admet-1317	8	2	microneedle	microneedle	PROPN
admet-1317	8	3	arrays	array	VERB
admet-1317	8	4	demonstrated	demonstrate	VERB
admet-1317	8	5	a	a	DET
admet-1317	8	6	suitable	suitable	ADJ
admet-1317	8	7	mechanical	mechanical	ADJ
admet-1317	8	8	strength	strength	NOUN
admet-1317	8	9	after	after	ADP
admet-1317	8	10	applying	apply	VERB
admet-1317	8	11	a	a	DET
admet-1317	8	12	force	force	NOUN
admet-1317	8	13	of	of	ADP
admet-1317	8	14	32	32	NUM
admet-1317	8	15	n	n	NOUN
admet-1317	8	16	per	per	ADP
admet-1317	8	17	array	array	NOUN
admet-1317	8	18	and	and	CCONJ
admet-1317	8	19	an	an	DET
admet-1317	8	20	excellent	excellent	ADJ
admet-1317	8	21	insertion	insertion	NOUN
admet-1317	8	22	ability	ability	NOUN
admet-1317	8	23	both	both	CCONJ
admet-1317	8	24	in	in	ADP
admet-1317	8	25	parafilm	parafilm	NOUN
admet-1317	8	26	m	m	PROPN
admet-1317	8	27	®	®	NOUN
admet-1317	8	28	and	and	CCONJ
admet-1317	8	29	human	human	ADJ
admet-1317	8	30	skin	skin	NOUN
admet-1317	8	31	.	.	PUNCT
admet-1317	9	1	the	the	PRON
admet-1317	9	2	in	in	ADP
admet-1317	9	3	vivo	vivo	ADJ
admet-1317	9	4	dissolution	dissolution	NOUN
admet-1317	9	5	of	of	ADP
admet-1317	9	6	microneedles	microneedle	NOUN
admet-1317	9	7	was	be	AUX
admet-1317	9	8	started	start	VERB
admet-1317	9	9	rapidly	rapidly	ADV
admet-1317	9	10	within	within	ADP
admet-1317	9	11	5	5	NUM
admet-1317	9	12	minutes	minute	NOUN
admet-1317	9	13	following	follow	VERB
admet-1317	9	14	the	the	DET
admet-1317	9	15	insertion	insertion	NOUN
admet-1317	9	16	in	in	ADP
admet-1317	9	17	the	the	DET
admet-1317	9	18	skin	skin	NOUN
admet-1317	9	19	and	and	CCONJ
admet-1317	9	20	completed	complete	VERB
admet-1317	9	21	at	at	ADP
admet-1317	9	22	1	1	NUM
admet-1317	9	23	hour	hour	NOUN
admet-1317	9	24	.	.	PUNCT
admet-1317	10	1	ex	ex	PRON
admet-1317	10	2	vivo	vivo	ADJ
admet-1317	10	3	permeation	permeation	NOUN
admet-1317	10	4	study	study	NOUN
admet-1317	10	5	using	use	VERB
admet-1317	10	6	human	human	ADJ
admet-1317	10	7	skin	skin	NOUN
admet-1317	10	8	has	have	AUX
admet-1317	10	9	shown	show	VERB
admet-1317	10	10	a	a	DET
admet-1317	10	11	significant	significant	ADJ
admet-1317	10	12	improvement	improvement	NOUN
admet-1317	10	13	in	in	ADP
admet-1317	10	14	lt-4	lt-4	NOUN
admet-1317	10	15	sodium	sodium	NOUN
admet-1317	10	16	delivery	delivery	NOUN
admet-1317	10	17	across	across	ADP
admet-1317	10	18	the	the	DET
admet-1317	10	19	skin	skin	NOUN
admet-1317	10	20	compared	compare	VERB
admet-1317	10	21	to	to	PART
admet-1317	10	22	control	control	VERB
admet-1317	10	23	preparations	preparation	NOUN
admet-1317	10	24	(	(	PUNCT
admet-1317	10	25	drug	drug	NOUN
admet-1317	10	26	solution	solution	NOUN
admet-1317	10	27	and	and	CCONJ
admet-1317	10	28	microneedle	microneedle	VERB
admet-1317	10	29	free	free	ADJ
admet-1317	10	30	film	film	NOUN
admet-1317	10	31	)	)	PUNCT
admet-1317	10	32	.	.	PUNCT
admet-1317	11	1	the	the	DET
admet-1317	11	2	microneedle	microneedle	PROPN
admet-1317	11	3	array	array	PROPN
admet-1317	11	4	f11	f11	PROPN
admet-1317	11	5	has	have	VERB
admet-1317	11	6	significantly	significantly	ADV
admet-1317	11	7	(	(	PUNCT
admet-1317	11	8	p	p	NOUN
admet-1317	11	9	≤	≤	NUM
admet-1317	11	10	0.05	0.05	NUM
admet-1317	11	11	)	)	PUNCT
admet-1317	11	12	increased	increase	VERB
admet-1317	11	13	lt-4	lt-4	NOUN
admet-1317	11	14	sodium	sodium	NOUN
admet-1317	11	15	permeation	permeation	NOUN
admet-1317	11	16	through	through	ADP
admet-1317	11	17	the	the	DET
admet-1317	11	18	skin	skin	NOUN
admet-1317	11	19	(	(	PUNCT
admet-1317	11	20	cumulative	cumulative	ADJ
admet-1317	11	21	permeated	permeate	VERB
admet-1317	11	22	amount	amount	NOUN
admet-1317	11	23	of	of	ADP
admet-1317	11	24	32	32	NUM
admet-1317	11	25	±	±	NUM
admet-1317	11	26	2	2	NUM
admet-1317	11	27	µg	µg	NOUN
admet-1317	11	28	/	/	SYM
admet-1317	11	29	cm²	cm²	PROPN
admet-1317	11	30	)	)	PUNCT
admet-1317	11	31	in	in	ADP
admet-1317	11	32	comparison	comparison	NOUN
admet-1317	11	33	to	to	ADP
admet-1317	11	34	the	the	DET
admet-1317	11	35	control	control	NOUN
admet-1317	11	36	solution	solution	NOUN
admet-1317	11	37	(	(	PUNCT
admet-1317	11	38	cumulative	cumulative	ADJ
admet-1317	11	39	permeated	permeate	VERB
admet-1317	11	40	amount	amount	NOUN
admet-1317	11	41	of	of	ADP
admet-1317	11	42	0.7	0.7	NUM
admet-1317	11	43	±	±	NUM
admet-1317	11	44	0.07	0.07	NUM
admet-1317	11	45	µg	µg	NOUN
admet-1317	11	46	/	/	SYM
admet-1317	11	47	cm²	cm²	PROPN
admet-1317	11	48	)	)	PUNCT
admet-1317	11	49	and	and	CCONJ
admet-1317	11	50	the	the	DET
admet-1317	11	51	microneedle	microneedle	ADJ
admet-1317	11	52	free	free	ADJ
admet-1317	11	53	film	film	NOUN
admet-1317	11	54	(	(	PUNCT
admet-1317	11	55	cumulative	cumulative	ADJ
admet-1317	11	56	permeated	permeate	VERB
admet-1317	11	57	amount	amount	NOUN
admet-1317	11	58	of	of	ADP
admet-1317	11	59	0.1	0.1	NUM
admet-1317	11	60	±	±	NUM
admet-1317	11	61	0.02	0.02	NUM
admet-1317	11	62	µg	µg	ADJ
admet-1317	11	63	/	/	SYM
admet-1317	11	64	cm²	cm²	PROPN
admet-1317	11	65	)	)	PUNCT
admet-1317	11	66	over	over	ADP
admet-1317	11	67	7	7	NUM
admet-1317	11	68	hours	hour	NOUN
admet-1317	11	69	.	.	PUNCT
admet-1317	12	1	the	the	DET
admet-1317	12	2	findings	finding	NOUN
admet-1317	12	3	from	from	ADP
admet-1317	12	4	the	the	DET
admet-1317	12	5	irritation	irritation	NOUN
admet-1317	12	6	test	test	NOUN
admet-1317	12	7	revealed	reveal	VERB
admet-1317	12	8	that	that	SCONJ
admet-1317	12	9	mild	mild	ADJ
admet-1317	12	10	erythema	erythema	NOUN
admet-1317	12	11	was	be	AUX
admet-1317	12	12	produced	produce	VERB
admet-1317	12	13	from	from	ADP
admet-1317	12	14	the	the	DET
admet-1317	12	15	application	application	NOUN
admet-1317	12	16	of	of	ADP
admet-1317	12	17	microneedle	microneedle	NOUN
admet-1317	12	18	arrays	array	NOUN
admet-1317	12	19	which	which	PRON
admet-1317	12	20	disappeared	disappear	VERB
admet-1317	12	21	within	within	ADP
admet-1317	12	22	24	24	NUM
admet-1317	12	23	hours	hour	NOUN
admet-1317	12	24	.	.	PUNCT
admet-1317	13	1	accordingly	accordingly	ADV
admet-1317	13	2	,	,	PUNCT
admet-1317	13	3	dissolving	dissolve	VERB
admet-1317	13	4	hyaluronic	hyaluronic	ADJ
admet-1317	13	5	acid	acid	NOUN
admet-1317	13	6	microneedles	microneedle	NOUN
admet-1317	13	7	could	could	AUX
admet-1317	13	8	be	be	AUX
admet-1317	13	9	a	a	DET
admet-1317	13	10	feasible	feasible	ADJ
admet-1317	13	11	and	and	CCONJ
admet-1317	13	12	effective	effective	ADJ
admet-1317	13	13	approach	approach	NOUN
admet-1317	13	14	to	to	ADP
admet-1317	13	15	delivering	deliver	VERB
admet-1317	13	16	lt-4	lt-4	NOUN
admet-1317	13	17	sodium	sodium	NOUN
admet-1317	13	18	transdermally	transdermally	ADV
admet-1317	13	19	without	without	ADP
admet-1317	13	20	causing	cause	VERB
admet-1317	13	21	significant	significant	ADJ
admet-1317	13	22	skin	skin	NOUN
admet-1317	13	23	damage	damage	NOUN
admet-1317	13	24	.	.	PUNCT
admet-1317	14	1	©	©	NOUN
admet-1317	14	2	2022	2022	NUM
admet-1317	14	3	by	by	ADP
admet-1317	14	4	the	the	DET
admet-1317	14	5	authors	author	NOUN
admet-1317	14	6	.	.	PUNCT
admet-1317	15	1	this	this	DET
admet-1317	15	2	article	article	NOUN
admet-1317	15	3	is	be	AUX
admet-1317	15	4	an	an	DET
admet-1317	15	5	open	open	ADJ
admet-1317	15	6	-	-	PUNCT
admet-1317	15	7	access	access	NOUN
admet-1317	15	8	article	article	NOUN
admet-1317	15	9	distributed	distribute	VERB
admet-1317	15	10	under	under	ADP
admet-1317	15	11	the	the	DET
admet-1317	15	12	terms	term	NOUN
admet-1317	15	13	and	and	CCONJ
admet-1317	15	14	conditions	condition	NOUN
admet-1317	15	15	of	of	ADP
admet-1317	15	16	the	the	DET
admet-1317	15	17	creative	creative	ADJ
admet-1317	15	18	commons	common	NOUN
admet-1317	15	19	attribution	attribution	NOUN
admet-1317	15	20	license	license	NOUN
admet-1317	15	21	(	(	PUNCT
admet-1317	15	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-1317	15	23	)	)	PUNCT
admet-1317	15	24	.	.	PUNCT
admet-1317	16	1	keywords	keyword	NOUN
admet-1317	16	2	hyaluronic	hyaluronic	ADJ
admet-1317	16	3	acid	acid	NOUN
admet-1317	16	4	;	;	PUNCT
admet-1317	16	5	levothyroxine	levothyroxine	NOUN
admet-1317	16	6	sodium	sodium	NOUN
admet-1317	16	7	;	;	PUNCT
admet-1317	16	8	dissolving	dissolve	VERB
admet-1317	16	9	microneedles	microneedle	NOUN
admet-1317	16	10	;	;	PUNCT
admet-1317	16	11	micromoulding	micromoulde	VERB
admet-1317	16	12	;	;	PUNCT
admet-1317	16	13	transdermal	transdermal	ADJ
admet-1317	16	14	delivery	delivery	NOUN
admet-1317	16	15	introduction	introduction	NOUN
admet-1317	16	16	levothyroxine	levothyroxine	NOUN
admet-1317	16	17	(	(	PUNCT
admet-1317	16	18	lt-4	lt-4	NOUN
admet-1317	16	19	)	)	PUNCT
admet-1317	16	20	sodium	sodium	NOUN
admet-1317	16	21	is	be	AUX
admet-1317	16	22	predominantly	predominantly	ADV
admet-1317	16	23	used	use	VERB
admet-1317	16	24	as	as	ADP
admet-1317	16	25	replacement	replacement	NOUN
admet-1317	16	26	therapy	therapy	NOUN
admet-1317	16	27	for	for	ADP
admet-1317	16	28	the	the	DET
admet-1317	16	29	treatment	treatment	NOUN
admet-1317	16	30	of	of	ADP
admet-1317	16	31	hypothyroidism	hypothyroidism	NOUN
admet-1317	16	32	,	,	PUNCT
admet-1317	16	33	chronic	chronic	ADJ
admet-1317	16	34	lymphocytic	lymphocytic	ADJ
admet-1317	16	35	thyroiditis	thyroiditis	NOUN
admet-1317	16	36	and	and	CCONJ
admet-1317	16	37	simple	simple	ADJ
admet-1317	16	38	non	non	ADJ
admet-1317	16	39	-	-	ADJ
admet-1317	16	40	endemic	endemic	ADJ
admet-1317	16	41	goiters	goiter	NOUN
admet-1317	16	42	.	.	PUNCT
admet-1317	17	1	it	it	PRON
admet-1317	17	2	is	be	AUX
admet-1317	17	3	administered	administer	VERB
admet-1317	17	4	in	in	ADP
admet-1317	17	5	small	small	ADJ
admet-1317	17	6	doses	dose	NOUN
admet-1317	17	7	(	(	PUNCT
admet-1317	17	8	micrograms	microgram	NOUN
admet-1317	17	9	)	)	PUNCT
admet-1317	17	10	,	,	PUNCT
admet-1317	17	11	which	which	PRON
admet-1317	17	12	provides	provide	VERB
admet-1317	17	13	a	a	DET
admet-1317	17	14	greater	great	ADJ
admet-1317	17	15	opportunity	opportunity	NOUN
admet-1317	17	16	for	for	ADP
admet-1317	17	17	clinically	clinically	ADV
admet-1317	17	18	significant	significant	ADJ
admet-1317	17	19	interactions	interaction	NOUN
admet-1317	17	20	through	through	ADP
admet-1317	17	21	the	the	DET
admet-1317	17	22	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	NUM
admet-1317	17	23	https://doi.org/10.5599/admet.1317	https://doi.org/10.5599/admet.1317	ADJ
admet-1317	17	24	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-1317	17	25	mailto:mohammedhussain@uomustansiriyah.edu.iq	mailto:mohammedhussain@uomustansiriyah.edu.iq	PROPN
admet-1317	17	26	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-1317	17	27	r.f	r.f	PROPN
admet-1317	17	28	.	.	PROPN
admet-1317	17	29	ghazi	ghazi	PROPN
admet-1317	17	30	and	and	CCONJ
admet-1317	17	31	m.h	m.h	PROPN
admet-1317	17	32	.	.	PROPN
admet-1317	17	33	al	al	PROPN
admet-1317	17	34	-	-	PUNCT
admet-1317	17	35	mayahy	mayahy	PROPN
admet-1317	17	36	admet	admet	PROPN
admet-1317	17	37	&	&	CCONJ
admet-1317	17	38	dmpk	dmpk	PROPN
admet-1317	17	39	10(3	10(3	NUM
admet-1317	17	40	)	)	PUNCT
admet-1317	17	41	(	(	PUNCT
admet-1317	17	42	2022	2022	NUM
admet-1317	17	43	)	)	PUNCT
admet-1317	17	44	213	213	NUM
admet-1317	17	45	-	-	SYM
admet-1317	17	46	230	230	NUM
admet-1317	17	47	214	214	NUM
admet-1317	17	48	absorption	absorption	NOUN
admet-1317	17	49	phase	phase	NOUN
admet-1317	17	50	to	to	PART
admet-1317	17	51	occur	occur	VERB
admet-1317	17	52	[	[	X
admet-1317	17	53	1	1	NUM
admet-1317	17	54	]	]	PUNCT
admet-1317	17	55	.	.	PUNCT
admet-1317	18	1	several	several	ADJ
admet-1317	18	2	gastrointestinal	gastrointestinal	ADJ
admet-1317	18	3	conditions	condition	NOUN
admet-1317	18	4	such	such	ADJ
admet-1317	18	5	as	as	ADP
admet-1317	18	6	celiac	celiac	ADJ
admet-1317	18	7	disease	disease	NOUN
admet-1317	18	8	,	,	PUNCT
admet-1317	18	9	atrophic	atrophic	ADJ
admet-1317	18	10	gastritis	gastritis	NOUN
admet-1317	18	11	,	,	PUNCT
admet-1317	18	12	lactose	lactose	ADJ
admet-1317	18	13	intolerance	intolerance	NOUN
admet-1317	18	14	and	and	CCONJ
admet-1317	18	15	pyloric	pyloric	ADJ
admet-1317	18	16	infection	infection	NOUN
admet-1317	18	17	in	in	ADP
admet-1317	18	18	helicobacter	helicobacter	NOUN
admet-1317	18	19	could	could	AUX
admet-1317	18	20	limit	limit	VERB
admet-1317	18	21	the	the	DET
admet-1317	18	22	oral	oral	ADJ
admet-1317	18	23	absorption	absorption	NOUN
admet-1317	18	24	of	of	ADP
admet-1317	18	25	lt-4	lt-4	NOUN
admet-1317	18	26	sodium	sodium	NOUN
admet-1317	19	1	[	[	X
admet-1317	19	2	1,2	1,2	NUM
admet-1317	19	3	]	]	PUNCT
admet-1317	19	4	.	.	PUNCT
admet-1317	20	1	simultaneous	simultaneous	ADJ
admet-1317	20	2	administration	administration	NOUN
admet-1317	20	3	of	of	ADP
admet-1317	20	4	oral	oral	ADJ
admet-1317	20	5	drugs	drug	NOUN
admet-1317	20	6	and	and	CCONJ
admet-1317	20	7	food	food	NOUN
admet-1317	20	8	intake	intake	NOUN
admet-1317	20	9	can	can	AUX
admet-1317	20	10	significantly	significantly	ADV
admet-1317	20	11	affect	affect	VERB
admet-1317	20	12	lt-4	lt-4	NOUN
admet-1317	20	13	bioavailability	bioavailability	NOUN
admet-1317	20	14	,	,	PUNCT
admet-1317	20	15	including	include	VERB
admet-1317	20	16	the	the	DET
admet-1317	20	17	onset	onset	NOUN
admet-1317	20	18	,	,	PUNCT
admet-1317	20	19	rate	rate	NOUN
admet-1317	20	20	and	and	CCONJ
admet-1317	20	21	extent	extent	NOUN
admet-1317	20	22	of	of	ADP
admet-1317	20	23	drug	drug	NOUN
admet-1317	20	24	absorption	absorption	NOUN
admet-1317	20	25	.	.	PUNCT
admet-1317	21	1	thyroxine	thyroxine	NOUN
admet-1317	21	2	malabsorption	malabsorption	NOUN
admet-1317	21	3	has	have	AUX
admet-1317	21	4	been	be	AUX
admet-1317	21	5	noticed	notice	VERB
admet-1317	21	6	following	follow	VERB
admet-1317	21	7	jejunoileal	jejunoileal	NOUN
admet-1317	21	8	bypass	bypass	NOUN
admet-1317	21	9	procedures	procedure	NOUN
admet-1317	21	10	,	,	PUNCT
admet-1317	21	11	in	in	ADP
admet-1317	21	12	short	short	ADJ
admet-1317	21	13	-	-	PUNCT
admet-1317	21	14	bowel	bowel	NOUN
admet-1317	21	15	syndrome	syndrome	NOUN
admet-1317	21	16	,	,	PUNCT
admet-1317	21	17	in	in	ADP
admet-1317	21	18	association	association	NOUN
admet-1317	21	19	with	with	ADP
admet-1317	21	20	vitamin	vitamin	NOUN
admet-1317	21	21	b12	b12	NOUN
admet-1317	21	22	malabsorption	malabsorption	NOUN
admet-1317	21	23	,	,	PUNCT
admet-1317	21	24	in	in	ADP
admet-1317	21	25	severe	severe	ADJ
admet-1317	21	26	hepatic	hepatic	ADJ
admet-1317	21	27	cirrhosis	cirrhosis	NOUN
admet-1317	21	28	,	,	PUNCT
admet-1317	21	29	as	as	ADV
admet-1317	21	30	well	well	ADV
admet-1317	21	31	as	as	ADP
admet-1317	21	32	in	in	ADP
admet-1317	21	33	congestive	congestive	ADJ
admet-1317	21	34	heart	heart	NOUN
admet-1317	21	35	failure	failure	NOUN
admet-1317	21	36	[	[	X
admet-1317	21	37	3	3	NUM
admet-1317	21	38	]	]	PUNCT
admet-1317	21	39	.	.	PUNCT
admet-1317	22	1	therefore	therefore	ADV
admet-1317	22	2	,	,	PUNCT
admet-1317	22	3	it	it	PRON
admet-1317	22	4	is	be	AUX
admet-1317	22	5	required	require	VERB
admet-1317	22	6	to	to	PART
admet-1317	22	7	develop	develop	VERB
admet-1317	22	8	an	an	DET
admet-1317	22	9	alternative	alternative	ADJ
admet-1317	22	10	delivery	delivery	NOUN
admet-1317	22	11	system	system	NOUN
admet-1317	22	12	for	for	ADP
admet-1317	22	13	a	a	DET
admet-1317	22	14	more	more	ADV
admet-1317	22	15	efficient	efficient	ADJ
admet-1317	22	16	administration	administration	NOUN
admet-1317	22	17	of	of	ADP
admet-1317	22	18	lt-4	lt-4	NOUN
admet-1317	22	19	sodium	sodium	NOUN
admet-1317	22	20	,	,	PUNCT
admet-1317	22	21	for	for	ADP
admet-1317	22	22	instance	instance	NOUN
admet-1317	22	23	,	,	PUNCT
admet-1317	22	24	via	via	ADP
admet-1317	22	25	the	the	DET
admet-1317	22	26	transdermal	transdermal	ADJ
admet-1317	22	27	route	route	NOUN
admet-1317	22	28	.	.	PUNCT
admet-1317	23	1	however	however	ADV
admet-1317	23	2	,	,	PUNCT
admet-1317	23	3	lt-4	lt-4	ADV
admet-1317	23	4	is	be	AUX
admet-1317	23	5	regarded	regard	VERB
admet-1317	23	6	as	as	ADP
admet-1317	23	7	a	a	DET
admet-1317	23	8	poor	poor	ADJ
admet-1317	23	9	candidate	candidate	NOUN
admet-1317	23	10	for	for	ADP
admet-1317	23	11	transdermal	transdermal	ADJ
admet-1317	23	12	drug	drug	NOUN
admet-1317	23	13	delivery	delivery	NOUN
admet-1317	23	14	due	due	ADP
admet-1317	23	15	to	to	ADP
admet-1317	23	16	its	its	PRON
admet-1317	23	17	inappropriate	inappropriate	ADJ
admet-1317	23	18	permeability	permeability	NOUN
admet-1317	23	19	characteristics	characteristic	NOUN
admet-1317	23	20	.	.	PUNCT
admet-1317	24	1	thus	thus	ADV
admet-1317	24	2	,	,	PUNCT
admet-1317	24	3	an	an	DET
admet-1317	24	4	active	active	ADJ
admet-1317	24	5	skin	skin	NOUN
admet-1317	24	6	permeation	permeation	NOUN
admet-1317	24	7	enhancement	enhancement	NOUN
admet-1317	24	8	strategy	strategy	NOUN
admet-1317	24	9	is	be	AUX
admet-1317	24	10	needed	need	VERB
admet-1317	24	11	for	for	SCONJ
admet-1317	24	12	its	its	PRON
admet-1317	24	13	delivery	delivery	NOUN
admet-1317	24	14	across	across	ADP
admet-1317	24	15	the	the	DET
admet-1317	24	16	skin	skin	NOUN
admet-1317	24	17	,	,	PUNCT
admet-1317	24	18	such	such	ADJ
admet-1317	24	19	as	as	ADP
admet-1317	24	20	microneedle	microneedle	NOUN
admet-1317	24	21	arrays	array	NOUN
admet-1317	24	22	.	.	PUNCT
admet-1317	25	1	microneedles	microneedle	NOUN
admet-1317	25	2	(	(	PUNCT
admet-1317	25	3	mns	mns	PROPN
admet-1317	25	4	)	)	PUNCT
admet-1317	25	5	represent	represent	VERB
admet-1317	25	6	a	a	DET
admet-1317	25	7	unique	unique	ADJ
admet-1317	25	8	technology	technology	NOUN
admet-1317	25	9	for	for	ADP
admet-1317	25	10	enhancing	enhance	VERB
admet-1317	25	11	the	the	DET
admet-1317	25	12	drug	drug	NOUN
admet-1317	25	13	permeability	permeability	NOUN
admet-1317	25	14	through	through	ADP
admet-1317	25	15	the	the	DET
admet-1317	25	16	stratum	stratum	NOUN
admet-1317	25	17	corneum	corneum	NOUN
admet-1317	25	18	.	.	PUNCT
admet-1317	26	1	mns	mns	PROPN
admet-1317	26	2	based	base	VERB
admet-1317	26	3	drug	drug	NOUN
admet-1317	26	4	delivery	delivery	NOUN
admet-1317	26	5	consists	consist	VERB
admet-1317	26	6	of	of	ADP
admet-1317	26	7	sharp	sharp	ADJ
admet-1317	26	8	-	-	PUNCT
admet-1317	26	9	tip	tip	NOUN
admet-1317	26	10	needles	needle	NOUN
admet-1317	26	11	that	that	PRON
admet-1317	26	12	puncture	puncture	VERB
admet-1317	26	13	the	the	DET
admet-1317	26	14	top	top	ADJ
admet-1317	26	15	layers	layer	NOUN
admet-1317	26	16	of	of	ADP
admet-1317	26	17	the	the	DET
admet-1317	26	18	skin	skin	NOUN
admet-1317	26	19	in	in	ADP
admet-1317	26	20	a	a	DET
admet-1317	26	21	minimally	minimally	ADV
admet-1317	26	22	invasive	invasive	ADJ
admet-1317	26	23	manner	manner	NOUN
admet-1317	26	24	to	to	PART
admet-1317	26	25	create	create	VERB
admet-1317	26	26	physical	physical	ADJ
admet-1317	26	27	channels	channel	NOUN
admet-1317	26	28	through	through	ADP
admet-1317	26	29	which	which	PRON
admet-1317	26	30	therapeutic	therapeutic	ADJ
admet-1317	26	31	molecules	molecule	NOUN
admet-1317	26	32	can	can	AUX
admet-1317	26	33	easily	easily	ADV
admet-1317	26	34	diffuse	diffuse	VERB
admet-1317	26	35	into	into	ADP
admet-1317	26	36	/	/	SYM
admet-1317	26	37	across	across	ADP
admet-1317	26	38	the	the	DET
admet-1317	26	39	skin	skin	NOUN
admet-1317	26	40	[	[	X
admet-1317	26	41	4,5	4,5	NUM
admet-1317	26	42	]	]	PUNCT
admet-1317	26	43	.	.	PUNCT
admet-1317	27	1	typically	typically	ADV
admet-1317	27	2	,	,	PUNCT
admet-1317	27	3	this	this	DET
admet-1317	27	4	approach	approach	NOUN
admet-1317	27	5	uses	use	VERB
admet-1317	27	6	1	1	NUM
admet-1317	27	7	to	to	PART
admet-1317	27	8	400	400	NUM
admet-1317	27	9	needles	needle	NOUN
admet-1317	27	10	(	(	PUNCT
admet-1317	27	11	100	100	NUM
admet-1317	27	12	μm	μm	NOUN
admet-1317	27	13	to	to	ADP
admet-1317	27	14	1	1	NUM
admet-1317	27	15	mm	mm	NOUN
admet-1317	27	16	apart	apart	ADV
admet-1317	27	17	)	)	PUNCT
admet-1317	27	18	which	which	PRON
admet-1317	27	19	may	may	AUX
admet-1317	27	20	range	range	VERB
admet-1317	27	21	from	from	ADP
admet-1317	27	22	150	150	NUM
admet-1317	27	23	μm	μm	NOUN
admet-1317	27	24	to	to	ADP
admet-1317	27	25	1000	1000	NUM
admet-1317	27	26	μm	μm	NOUN
admet-1317	27	27	in	in	ADP
admet-1317	27	28	length	length	NOUN
admet-1317	27	29	with	with	ADP
admet-1317	27	30	a	a	DET
admet-1317	27	31	diameter	diameter	NOUN
admet-1317	27	32	from	from	ADP
admet-1317	27	33	50	50	NUM
admet-1317	27	34	μm	μm	NOUN
admet-1317	27	35	to	to	ADP
admet-1317	27	36	80	80	NUM
admet-1317	27	37	μm	μm	NUM
admet-1317	27	38	.	.	PUNCT
admet-1317	28	1	the	the	DET
admet-1317	28	2	mn	mn	PROPN
admet-1317	28	3	array	array	NOUN
admet-1317	28	4	is	be	AUX
admet-1317	28	5	placed	place	VERB
admet-1317	28	6	on	on	ADP
admet-1317	28	7	the	the	DET
admet-1317	28	8	skin	skin	NOUN
admet-1317	28	9	surface	surface	NOUN
admet-1317	28	10	such	such	ADJ
admet-1317	28	11	that	that	SCONJ
admet-1317	28	12	mns	mns	PROPN
admet-1317	28	13	penetrate	penetrate	VERB
admet-1317	28	14	the	the	DET
admet-1317	28	15	stratum	stratum	NOUN
admet-1317	28	16	corneum	corneum	NOUN
admet-1317	28	17	layer	layer	NOUN
admet-1317	28	18	,	,	PUNCT
admet-1317	28	19	bypassing	bypass	VERB
admet-1317	28	20	it	it	PRON
admet-1317	28	21	and	and	CCONJ
admet-1317	28	22	delivering	deliver	VERB
admet-1317	28	23	therapeutic	therapeutic	ADJ
admet-1317	28	24	agents	agent	NOUN
admet-1317	28	25	into	into	ADP
admet-1317	28	26	the	the	DET
admet-1317	28	27	viable	viable	ADJ
admet-1317	28	28	epidermis	epidermis	NOUN
admet-1317	28	29	directly	directly	ADV
admet-1317	28	30	.	.	PUNCT
admet-1317	29	1	since	since	SCONJ
admet-1317	29	2	the	the	DET
admet-1317	29	3	epidermis	epidermis	NOUN
admet-1317	29	4	has	have	VERB
admet-1317	29	5	no	no	DET
admet-1317	29	6	nociceptors	nociceptor	NOUN
admet-1317	29	7	(	(	PUNCT
admet-1317	29	8	pain	pain	NOUN
admet-1317	29	9	receptors	receptor	NOUN
admet-1317	29	10	)	)	PUNCT
admet-1317	29	11	and	and	CCONJ
admet-1317	29	12	the	the	DET
admet-1317	29	13	mns	mns	PROPN
admet-1317	29	14	are	be	AUX
admet-1317	29	15	frequently	frequently	ADV
admet-1317	29	16	do	do	AUX
admet-1317	29	17	not	not	PART
admet-1317	29	18	reach	reach	VERB
admet-1317	29	19	the	the	DET
admet-1317	29	20	dermis	dermis	NOUN
admet-1317	29	21	,	,	PUNCT
admet-1317	29	22	pain	pain	NOUN
admet-1317	29	23	sensation	sensation	NOUN
admet-1317	29	24	is	be	AUX
admet-1317	29	25	not	not	PART
admet-1317	29	26	triggered	trigger	VERB
admet-1317	29	27	and	and	CCONJ
admet-1317	29	28	therefore	therefore	ADV
admet-1317	29	29	,	,	PUNCT
admet-1317	29	30	they	they	PRON
admet-1317	29	31	are	be	AUX
admet-1317	29	32	regarded	regard	VERB
admet-1317	29	33	as	as	ADP
admet-1317	29	34	a	a	DET
admet-1317	29	35	minimally	minimally	ADV
admet-1317	29	36	invasive	invasive	ADJ
admet-1317	29	37	technique	technique	NOUN
admet-1317	29	38	with	with	ADP
admet-1317	29	39	pain	pain	NOUN
admet-1317	29	40	-	-	PUNCT
admet-1317	29	41	free	free	ADJ
admet-1317	29	42	delivery	delivery	NOUN
admet-1317	29	43	.	.	PUNCT
admet-1317	30	1	morphologically	morphologically	ADV
admet-1317	30	2	microneedles	microneedle	NOUN
admet-1317	30	3	can	can	AUX
admet-1317	30	4	be	be	AUX
admet-1317	30	5	classified	classify	VERB
admet-1317	30	6	into	into	ADP
admet-1317	30	7	five	five	NUM
admet-1317	30	8	different	different	ADJ
admet-1317	30	9	types	type	NOUN
admet-1317	30	10	,	,	PUNCT
admet-1317	30	11	including	include	VERB
admet-1317	30	12	solid	solid	ADJ
admet-1317	30	13	microneedles	microneedle	NOUN
admet-1317	31	1	[	[	X
admet-1317	31	2	6	6	NUM
admet-1317	31	3	]	]	PUNCT
admet-1317	31	4	,	,	PUNCT
admet-1317	31	5	coated	coated	ADJ
admet-1317	31	6	microneedles	microneedle	NOUN
admet-1317	32	1	[	[	X
admet-1317	32	2	7	7	NUM
admet-1317	32	3	]	]	PUNCT
admet-1317	32	4	,	,	PUNCT
admet-1317	32	5	dissolving	dissolve	VERB
admet-1317	32	6	microneedles	microneedle	NOUN
admet-1317	32	7	[	[	X
admet-1317	32	8	8	8	NUM
admet-1317	32	9	]	]	PUNCT
admet-1317	32	10	,	,	PUNCT
admet-1317	32	11	hollow	hollow	ADJ
admet-1317	32	12	microneedles	microneedle	NOUN
admet-1317	33	1	[	[	X
admet-1317	33	2	9	9	NUM
admet-1317	33	3	]	]	PUNCT
admet-1317	33	4	and	and	CCONJ
admet-1317	33	5	hydrogel	hydrogel	NOUN
admet-1317	33	6	-	-	PUNCT
admet-1317	33	7	forming	form	VERB
admet-1317	33	8	microneedles	microneedle	NOUN
admet-1317	33	9	[	[	X
admet-1317	33	10	10	10	NUM
admet-1317	33	11	]	]	PUNCT
admet-1317	33	12	.	.	PUNCT
admet-1317	34	1	they	they	PRON
admet-1317	34	2	can	can	AUX
admet-1317	34	3	be	be	AUX
admet-1317	34	4	manufactured	manufacture	VERB
admet-1317	34	5	of	of	ADP
admet-1317	34	6	a	a	DET
admet-1317	34	7	variety	variety	NOUN
admet-1317	34	8	of	of	ADP
admet-1317	34	9	materials	material	NOUN
admet-1317	34	10	,	,	PUNCT
admet-1317	34	11	such	such	ADJ
admet-1317	34	12	as	as	ADP
admet-1317	34	13	metals	metal	NOUN
admet-1317	34	14	[	[	X
admet-1317	34	15	11	11	NUM
admet-1317	34	16	]	]	PUNCT
admet-1317	34	17	,	,	PUNCT
admet-1317	34	18	inorganic	inorganic	ADJ
admet-1317	34	19	materials	material	NOUN
admet-1317	34	20	[	[	X
admet-1317	34	21	12	12	NUM
admet-1317	34	22	]	]	PUNCT
admet-1317	34	23	and	and	CCONJ
admet-1317	34	24	polymeric	polymeric	ADJ
admet-1317	34	25	materials	material	NOUN
admet-1317	34	26	[	[	X
admet-1317	34	27	13	13	NUM
admet-1317	34	28	]	]	PUNCT
admet-1317	34	29	.	.	PUNCT
admet-1317	35	1	drug	drug	NOUN
admet-1317	35	2	-	-	PUNCT
admet-1317	35	3	loaded	load	VERB
admet-1317	35	4	dissolving	dissolve	VERB
admet-1317	35	5	mns	mn	NOUN
admet-1317	35	6	containing	contain	VERB
admet-1317	35	7	a	a	DET
admet-1317	35	8	drug	drug	NOUN
admet-1317	35	9	within	within	ADP
admet-1317	35	10	the	the	DET
admet-1317	35	11	needle	needle	NOUN
admet-1317	35	12	matrix	matrix	NOUN
admet-1317	35	13	can	can	AUX
admet-1317	35	14	overcome	overcome	VERB
admet-1317	35	15	the	the	DET
admet-1317	35	16	limitations	limitation	NOUN
admet-1317	35	17	associated	associate	VERB
admet-1317	35	18	with	with	ADP
admet-1317	35	19	other	other	ADJ
admet-1317	35	20	mn	mn	PROPN
admet-1317	35	21	types	type	NOUN
admet-1317	35	22	.	.	PUNCT
admet-1317	36	1	they	they	PRON
admet-1317	36	2	solve	solve	VERB
admet-1317	36	3	the	the	DET
admet-1317	36	4	problem	problem	NOUN
admet-1317	36	5	of	of	ADP
admet-1317	36	6	the	the	DET
admet-1317	36	7	two	two	NUM
admet-1317	36	8	-	-	PUNCT
admet-1317	36	9	step	step	NOUN
admet-1317	36	10	application	application	NOUN
admet-1317	36	11	of	of	ADP
admet-1317	36	12	solid	solid	ADJ
admet-1317	36	13	mns	mns	PROPN
admet-1317	36	14	.	.	PUNCT
admet-1317	37	1	as	as	ADP
admet-1317	37	2	a	a	DET
admet-1317	37	3	result	result	NOUN
admet-1317	37	4	,	,	PUNCT
admet-1317	37	5	a	a	DET
admet-1317	37	6	one	one	NUM
admet-1317	37	7	-	-	PUNCT
admet-1317	37	8	step	step	NOUN
admet-1317	37	9	application	application	NOUN
admet-1317	37	10	technique	technique	NOUN
admet-1317	37	11	will	will	AUX
admet-1317	37	12	be	be	AUX
admet-1317	37	13	available	available	ADJ
admet-1317	37	14	[	[	X
admet-1317	37	15	14	14	NUM
admet-1317	37	16	]	]	PUNCT
admet-1317	37	17	.	.	PUNCT
admet-1317	38	1	in	in	ADP
admet-1317	38	2	comparison	comparison	NOUN
admet-1317	38	3	to	to	ADP
admet-1317	38	4	coated	coated	ADJ
admet-1317	38	5	mns	mns	PROPN
admet-1317	38	6	,	,	PUNCT
admet-1317	38	7	a	a	DET
admet-1317	38	8	higher	high	ADJ
admet-1317	38	9	and	and	CCONJ
admet-1317	38	10	more	more	ADV
admet-1317	38	11	precise	precise	ADJ
admet-1317	38	12	drug	drug	NOUN
admet-1317	38	13	loading	loading	NOUN
admet-1317	38	14	can	can	AUX
admet-1317	38	15	be	be	AUX
admet-1317	38	16	achieved	achieve	VERB
admet-1317	38	17	by	by	ADP
admet-1317	38	18	dissolving	dissolve	VERB
admet-1317	38	19	mns	mn	NOUN
admet-1317	39	1	[	[	X
admet-1317	39	2	15	15	NUM
admet-1317	39	3	]	]	PUNCT
admet-1317	39	4	.	.	PUNCT
admet-1317	40	1	additionally	additionally	ADV
admet-1317	40	2	,	,	PUNCT
admet-1317	40	3	they	they	PRON
admet-1317	40	4	eliminate	eliminate	VERB
admet-1317	40	5	the	the	DET
admet-1317	40	6	need	need	NOUN
admet-1317	40	7	for	for	ADP
admet-1317	40	8	specialized	specialized	ADJ
admet-1317	40	9	techniques	technique	NOUN
admet-1317	40	10	used	use	VERB
admet-1317	40	11	in	in	ADP
admet-1317	40	12	hollow	hollow	ADJ
admet-1317	40	13	mns	mn	NOUN
admet-1317	40	14	to	to	PART
admet-1317	40	15	control	control	VERB
admet-1317	40	16	the	the	DET
admet-1317	40	17	flow	flow	NOUN
admet-1317	40	18	rate	rate	NOUN
admet-1317	40	19	and	and	CCONJ
admet-1317	40	20	pressure	pressure	NOUN
admet-1317	40	21	for	for	ADP
admet-1317	40	22	driving	drive	VERB
admet-1317	40	23	the	the	DET
admet-1317	40	24	flow	flow	NOUN
admet-1317	40	25	of	of	ADP
admet-1317	40	26	liquid	liquid	NOUN
admet-1317	40	27	into	into	ADP
admet-1317	40	28	the	the	DET
admet-1317	40	29	skin	skin	NOUN
admet-1317	40	30	.	.	PUNCT
admet-1317	41	1	however	however	ADV
admet-1317	41	2	,	,	PUNCT
admet-1317	41	3	some	some	PRON
admet-1317	41	4	of	of	ADP
admet-1317	41	5	the	the	DET
admet-1317	41	6	biodegradable	biodegradable	ADJ
admet-1317	41	7	polymers	polymer	NOUN
admet-1317	41	8	,	,	PUNCT
admet-1317	41	9	including	include	VERB
admet-1317	41	10	plga	plga	NOUN
admet-1317	41	11	,	,	PUNCT
admet-1317	41	12	polylactic	polylactic	ADJ
admet-1317	41	13	acid	acid	NOUN
admet-1317	41	14	,	,	PUNCT
admet-1317	41	15	polyglycolic	polyglycolic	NOUN
admet-1317	41	16	acid	acid	NOUN
admet-1317	41	17	and	and	CCONJ
admet-1317	41	18	polycarbonate	polycarbonate	NOUN
admet-1317	41	19	used	use	VERB
admet-1317	41	20	in	in	ADP
admet-1317	41	21	the	the	DET
admet-1317	41	22	manufacturing	manufacturing	NOUN
admet-1317	41	23	of	of	ADP
admet-1317	41	24	dissolving	dissolve	VERB
admet-1317	41	25	mns	mns	PROPN
admet-1317	41	26	are	be	AUX
admet-1317	41	27	unsuitable	unsuitable	ADJ
admet-1317	41	28	for	for	ADP
admet-1317	41	29	the	the	DET
admet-1317	41	30	fabrication	fabrication	NOUN
admet-1317	41	31	of	of	ADP
admet-1317	41	32	lt-4	lt-4	NOUN
admet-1317	41	33	sodium	sodium	NOUN
admet-1317	41	34	loaded	load	VERB
admet-1317	41	35	mns	mns	PROPN
admet-1317	41	36	,	,	PUNCT
admet-1317	41	37	particularly	particularly	ADV
admet-1317	41	38	during	during	ADP
admet-1317	41	39	the	the	DET
admet-1317	41	40	manufacturing	manufacturing	NOUN
admet-1317	41	41	process	process	NOUN
admet-1317	41	42	.	.	PUNCT
admet-1317	42	1	this	this	PRON
admet-1317	42	2	can	can	AUX
admet-1317	42	3	be	be	AUX
admet-1317	42	4	attributed	attribute	VERB
admet-1317	42	5	to	to	ADP
admet-1317	42	6	the	the	DET
admet-1317	42	7	need	need	NOUN
admet-1317	42	8	for	for	ADP
admet-1317	42	9	a	a	DET
admet-1317	42	10	heating	heating	NOUN
admet-1317	42	11	step	step	NOUN
admet-1317	42	12	that	that	PRON
admet-1317	42	13	may	may	AUX
admet-1317	42	14	cause	cause	VERB
admet-1317	42	15	a	a	DET
admet-1317	42	16	degradation	degradation	NOUN
admet-1317	42	17	of	of	ADP
admet-1317	42	18	heat	heat	NOUN
admet-1317	42	19	-	-	PUNCT
admet-1317	42	20	sensitive	sensitive	ADJ
admet-1317	42	21	drugs	drug	NOUN
admet-1317	42	22	such	such	ADJ
admet-1317	42	23	as	as	ADP
admet-1317	42	24	lt-4	lt-4	ADJ
admet-1317	42	25	sodium	sodium	NOUN
admet-1317	42	26	.	.	PUNCT
admet-1317	43	1	other	other	ADJ
admet-1317	43	2	materials	material	NOUN
admet-1317	43	3	used	use	VERB
admet-1317	43	4	in	in	ADP
admet-1317	43	5	the	the	DET
admet-1317	43	6	fabrication	fabrication	NOUN
admet-1317	43	7	of	of	ADP
admet-1317	43	8	dissolving	dissolve	VERB
admet-1317	43	9	mns	mn	NOUN
admet-1317	43	10	,	,	PUNCT
admet-1317	43	11	such	such	ADJ
admet-1317	43	12	as	as	ADP
admet-1317	43	13	carbohydrates	carbohydrate	NOUN
admet-1317	43	14	,	,	PUNCT
admet-1317	43	15	undergo	undergo	VERB
admet-1317	43	16	hydrolysis	hydrolysis	NOUN
admet-1317	43	17	in	in	ADP
admet-1317	43	18	a	a	DET
admet-1317	43	19	moist	moist	ADJ
admet-1317	43	20	environment	environment	NOUN
admet-1317	43	21	at	at	ADP
admet-1317	43	22	a	a	DET
admet-1317	43	23	humidity	humidity	NOUN
admet-1317	43	24	level	level	NOUN
admet-1317	43	25	exceeding	exceed	VERB
admet-1317	43	26	43	43	NUM
admet-1317	43	27	%	%	NOUN
admet-1317	43	28	,	,	PUNCT
admet-1317	43	29	resulting	result	VERB
admet-1317	43	30	in	in	ADP
admet-1317	43	31	needle	needle	NOUN
admet-1317	43	32	distortion	distortion	NOUN
admet-1317	43	33	or	or	CCONJ
admet-1317	43	34	disappearance	disappearance	NOUN
admet-1317	43	35	,	,	PUNCT
admet-1317	43	36	as	as	ADV
admet-1317	43	37	well	well	ADV
admet-1317	43	38	as	as	ADP
admet-1317	43	39	insufficient	insufficient	ADJ
admet-1317	43	40	insertion	insertion	NOUN
admet-1317	43	41	ability	ability	NOUN
admet-1317	43	42	into	into	ADP
admet-1317	43	43	the	the	DET
admet-1317	43	44	skin	skin	NOUN
admet-1317	43	45	[	[	X
admet-1317	43	46	16,17	16,17	NUM
admet-1317	43	47	]	]	PUNCT
admet-1317	43	48	.	.	PUNCT
admet-1317	43	49	hyaluronic	hyaluronic	ADJ
admet-1317	43	50	acid	acid	NOUN
admet-1317	43	51	(	(	PUNCT
admet-1317	43	52	ha	ha	INTJ
admet-1317	43	53	)	)	PUNCT
admet-1317	43	54	,	,	PUNCT
admet-1317	43	55	commonly	commonly	ADV
admet-1317	43	56	utilized	utilize	VERB
admet-1317	43	57	in	in	ADP
admet-1317	43	58	skincare	skincare	NOUN
admet-1317	43	59	products	product	NOUN
admet-1317	43	60	,	,	PUNCT
admet-1317	43	61	was	be	AUX
admet-1317	43	62	identified	identify	VERB
admet-1317	43	63	to	to	PART
admet-1317	43	64	generate	generate	VERB
admet-1317	43	65	mns	mns	PROPN
admet-1317	43	66	with	with	ADP
admet-1317	43	67	good	good	ADJ
admet-1317	43	68	biocompatibility	biocompatibility	NOUN
admet-1317	43	69	and	and	CCONJ
admet-1317	43	70	deformation	deformation	NOUN
admet-1317	43	71	resistance	resistance	NOUN
admet-1317	43	72	.	.	PUNCT
admet-1317	44	1	the	the	DET
admet-1317	44	2	obtained	obtain	VERB
admet-1317	44	3	ha	ha	INTJ
admet-1317	44	4	mns	mns	PROPN
admet-1317	44	5	were	be	AUX
admet-1317	44	6	easily	easily	ADV
admet-1317	44	7	prepared	prepare	VERB
admet-1317	44	8	without	without	ADP
admet-1317	44	9	the	the	DET
admet-1317	44	10	need	need	NOUN
admet-1317	44	11	of	of	ADP
admet-1317	44	12	a	a	DET
admet-1317	44	13	heating	heating	NOUN
admet-1317	44	14	step	step	NOUN
admet-1317	44	15	.	.	PUNCT
admet-1317	45	1	in	in	ADP
admet-1317	45	2	addition	addition	NOUN
admet-1317	45	3	,	,	PUNCT
admet-1317	45	4	they	they	PRON
admet-1317	45	5	have	have	VERB
admet-1317	45	6	sufficient	sufficient	ADJ
admet-1317	45	7	strength	strength	NOUN
admet-1317	45	8	to	to	PART
admet-1317	45	9	reliably	reliably	ADV
admet-1317	45	10	pierce	pierce	VERB
admet-1317	45	11	the	the	DET
admet-1317	45	12	skin	skin	NOUN
admet-1317	45	13	,	,	PUNCT
admet-1317	45	14	dissolve	dissolve	VERB
admet-1317	45	15	and	and	CCONJ
admet-1317	45	16	rapidly	rapidly	ADV
admet-1317	45	17	release	release	VERB
admet-1317	45	18	the	the	DET
admet-1317	45	19	contained	contain	VERB
admet-1317	45	20	drug	drug	NOUN
admet-1317	45	21	within	within	ADP
admet-1317	45	22	the	the	DET
admet-1317	45	23	skin	skin	NOUN
admet-1317	45	24	[	[	X
admet-1317	45	25	18,19	18,19	NUM
admet-1317	45	26	]	]	X
admet-1317	45	27	.	.	PUNCT
admet-1317	46	1	therefore	therefore	ADV
admet-1317	46	2	,	,	PUNCT
admet-1317	46	3	in	in	ADP
admet-1317	46	4	the	the	DET
admet-1317	46	5	present	present	ADJ
admet-1317	46	6	study	study	NOUN
admet-1317	46	7	,	,	PUNCT
admet-1317	46	8	novel	novel	ADJ
admet-1317	46	9	lt-4	lt-4	NOUN
admet-1317	46	10	sodium	sodium	NOUN
admet-1317	46	11	-	-	PUNCT
admet-1317	46	12	loaded	load	VERB
admet-1317	46	13	ha	ha	INTJ
admet-1317	46	14	mns	mns	PROPN
admet-1317	46	15	were	be	AUX
admet-1317	46	16	developed	develop	VERB
admet-1317	46	17	for	for	ADP
admet-1317	46	18	enhancing	enhance	VERB
admet-1317	46	19	transdermal	transdermal	ADJ
admet-1317	46	20	delivery	delivery	NOUN
admet-1317	46	21	.	.	PUNCT
admet-1317	47	1	to	to	ADP
admet-1317	47	2	the	the	DET
admet-1317	47	3	best	good	ADJ
admet-1317	47	4	of	of	ADP
admet-1317	47	5	our	our	PRON
admet-1317	47	6	knowledge	knowledge	NOUN
admet-1317	47	7	,	,	PUNCT
admet-1317	47	8	this	this	PRON
admet-1317	47	9	is	be	AUX
admet-1317	47	10	the	the	DET
admet-1317	47	11	first	first	ADJ
admet-1317	47	12	study	study	NOUN
admet-1317	47	13	conducted	conduct	VERB
admet-1317	47	14	to	to	PART
admet-1317	47	15	investigate	investigate	VERB
admet-1317	47	16	lt-4	lt-4	NOUN
admet-1317	47	17	delivery	delivery	NOUN
admet-1317	47	18	across	across	ADP
admet-1317	47	19	the	the	DET
admet-1317	47	20	skin	skin	NOUN
admet-1317	47	21	using	use	VERB
admet-1317	47	22	ha	ha	INTJ
admet-1317	47	23	mns	mns	PROPN
admet-1317	47	24	.	.	PROPN
admet-1317	48	1	admet	admet	PROPN
admet-1317	48	2	&	&	CCONJ
admet-1317	48	3	dmpk	dmpk	PROPN
admet-1317	48	4	10(3	10(3	NUM
admet-1317	48	5	)	)	PUNCT
admet-1317	48	6	(	(	PUNCT
admet-1317	48	7	2022	2022	NUM
admet-1317	48	8	)	)	PUNCT
admet-1317	48	9	213	213	NUM
admet-1317	48	10	-	-	SYM
admet-1317	48	11	230	230	NUM
admet-1317	48	12	transdermal	transdermal	ADJ
admet-1317	48	13	delivery	delivery	NOUN
admet-1317	48	14	of	of	ADP
admet-1317	48	15	levothyroxine	levothyroxine	NOUN
admet-1317	48	16	via	via	ADP
admet-1317	48	17	dissolving	dissolve	VERB
admet-1317	48	18	microneedles	microneedle	NOUN
admet-1317	48	19	doi	doi	PROPN
admet-1317	48	20	:	:	PUNCT
admet-1317	48	21	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	VERB
admet-1317	48	22	215	215	NUM
admet-1317	48	23	experimental	experimental	ADJ
admet-1317	48	24	materials	material	NOUN
admet-1317	48	25	levothyroxine	levothyroxine	NOUN
admet-1317	48	26	sodium	sodium	NOUN
admet-1317	48	27	and	and	CCONJ
admet-1317	48	28	hyaluronic	hyaluronic	ADJ
admet-1317	48	29	acid	acid	NOUN
admet-1317	48	30	20	20	NUM
admet-1317	48	31	kd	kd	PROPN
admet-1317	48	32	were	be	AUX
admet-1317	48	33	purchased	purchase	VERB
admet-1317	48	34	from	from	ADP
admet-1317	48	35	(	(	PUNCT
admet-1317	48	36	look	look	VERB
admet-1317	48	37	chemical	chemical	NOUN
admet-1317	48	38	,	,	PUNCT
admet-1317	48	39	china	china	PROPN
admet-1317	48	40	)	)	PUNCT
admet-1317	48	41	.	.	PUNCT
admet-1317	49	1	tween	tween	NOUN
admet-1317	49	2	80	80	NUM
admet-1317	49	3	was	be	AUX
admet-1317	49	4	obtained	obtain	VERB
admet-1317	49	5	from	from	ADP
admet-1317	49	6	(	(	PUNCT
admet-1317	49	7	chemical	chemical	NOUN
admet-1317	49	8	point	point	NOUN
admet-1317	49	9	,	,	PUNCT
admet-1317	49	10	united	united	ADJ
admet-1317	49	11	kingdom	kingdom	PROPN
admet-1317	49	12	)	)	PUNCT
admet-1317	49	13	.	.	PUNCT
admet-1317	50	1	blue	blue	ADJ
admet-1317	50	2	silica	silica	NOUN
admet-1317	50	3	gel	gel	NOUN
admet-1317	50	4	powder	powder	NOUN
admet-1317	50	5	was	be	AUX
admet-1317	50	6	purchased	purchase	VERB
admet-1317	50	7	from	from	ADP
admet-1317	50	8	(	(	PUNCT
admet-1317	50	9	om	om	PROPN
admet-1317	50	10	chemicals	chemical	NOUN
admet-1317	50	11	,	,	PUNCT
admet-1317	50	12	india	india	PROPN
admet-1317	50	13	)	)	PUNCT
admet-1317	50	14	and	and	CCONJ
admet-1317	50	15	formalin	formalin	NOUN
admet-1317	50	16	was	be	AUX
admet-1317	50	17	obtained	obtain	VERB
admet-1317	50	18	from	from	ADP
admet-1317	50	19	(	(	PUNCT
admet-1317	50	20	sigma	sigma	PROPN
admet-1317	50	21	-	-	PUNCT
admet-1317	50	22	aldrich	aldrich	PROPN
admet-1317	50	23	,	,	PUNCT
admet-1317	50	24	germany	germany	PROPN
admet-1317	50	25	)	)	PUNCT
admet-1317	50	26	.	.	PUNCT
admet-1317	51	1	all	all	DET
admet-1317	51	2	chemicals	chemical	NOUN
admet-1317	51	3	and	and	CCONJ
admet-1317	51	4	reagents	reagent	NOUN
admet-1317	51	5	used	use	VERB
admet-1317	51	6	were	be	AUX
admet-1317	51	7	of	of	ADP
admet-1317	51	8	analytical	analytical	ADJ
admet-1317	51	9	grade	grade	NOUN
admet-1317	51	10	.	.	PUNCT
admet-1317	52	1	preparation	preparation	NOUN
admet-1317	52	2	of	of	ADP
admet-1317	52	3	lt-4	lt-4	NOUN
admet-1317	52	4	sodium	sodium	NOUN
admet-1317	52	5	loaded	load	VERB
admet-1317	52	6	hyaluronic	hyaluronic	ADJ
admet-1317	52	7	acid	acid	NOUN
admet-1317	52	8	microneedle	microneedle	NOUN
admet-1317	52	9	arrays	array	VERB
admet-1317	52	10	mn	mn	PROPN
admet-1317	52	11	arrays	array	NOUN
admet-1317	52	12	were	be	AUX
admet-1317	52	13	manufactured	manufacture	VERB
admet-1317	52	14	by	by	ADP
admet-1317	52	15	micromoulding	micromoulde	VERB
admet-1317	52	16	technique	technique	NOUN
admet-1317	52	17	with	with	ADP
admet-1317	52	18	ha	ha	INTJ
admet-1317	52	19	as	as	ADP
admet-1317	52	20	the	the	DET
admet-1317	52	21	structural	structural	ADJ
admet-1317	52	22	material	material	NOUN
admet-1317	52	23	.	.	PUNCT
admet-1317	53	1	mns	mns	PROPN
admet-1317	53	2	manufacturing	manufacturing	NOUN
admet-1317	53	3	can	can	AUX
admet-1317	53	4	be	be	AUX
admet-1317	53	5	considered	consider	VERB
admet-1317	53	6	as	as	ADP
admet-1317	53	7	a	a	DET
admet-1317	53	8	transcription	transcription	NOUN
admet-1317	53	9	process	process	NOUN
admet-1317	53	10	from	from	ADP
admet-1317	53	11	the	the	DET
admet-1317	53	12	micromould	micromould	NOUN
admet-1317	53	13	[	[	X
admet-1317	53	14	20	20	NUM
admet-1317	53	15	]	]	PUNCT
admet-1317	53	16	.	.	PUNCT
admet-1317	54	1	initially	initially	ADV
admet-1317	54	2	,	,	PUNCT
admet-1317	54	3	lt-4	lt-4	NOUN
admet-1317	54	4	sodium	sodium	NOUN
admet-1317	54	5	was	be	AUX
admet-1317	54	6	dissolved	dissolve	VERB
admet-1317	54	7	in	in	ADP
admet-1317	54	8	deionised	deionise	VERB
admet-1317	54	9	water	water	NOUN
admet-1317	54	10	(	(	PUNCT
admet-1317	54	11	dw	dw	NOUN
admet-1317	54	12	)	)	PUNCT
admet-1317	54	13	with	with	ADP
admet-1317	54	14	the	the	DET
admet-1317	54	15	aid	aid	NOUN
admet-1317	54	16	of	of	ADP
admet-1317	54	17	tween	tween	NOUN
admet-1317	54	18	80	80	NUM
admet-1317	54	19	.	.	PUNCT
admet-1317	55	1	following	follow	VERB
admet-1317	55	2	this	this	PRON
admet-1317	55	3	,	,	PUNCT
admet-1317	55	4	ha	ha	INTJ
admet-1317	55	5	was	be	AUX
admet-1317	55	6	added	add	VERB
admet-1317	55	7	to	to	ADP
admet-1317	55	8	this	this	DET
admet-1317	55	9	solution	solution	NOUN
admet-1317	55	10	at	at	ADP
admet-1317	55	11	specific	specific	ADJ
admet-1317	55	12	percentages	percentage	NOUN
admet-1317	55	13	and	and	CCONJ
admet-1317	55	14	the	the	DET
admet-1317	55	15	volume	volume	NOUN
admet-1317	55	16	was	be	AUX
admet-1317	55	17	completed	complete	VERB
admet-1317	55	18	up	up	ADP
admet-1317	55	19	to	to	PART
admet-1317	55	20	100	100	NUM
admet-1317	55	21	%	%	NOUN
admet-1317	55	22	with	with	ADP
admet-1317	55	23	dw	dw	PROPN
admet-1317	55	24	to	to	PART
admet-1317	55	25	prepare	prepare	VERB
admet-1317	55	26	different	different	ADJ
admet-1317	55	27	polymeric	polymeric	ADJ
admet-1317	55	28	formulation	formulation	NOUN
admet-1317	55	29	mixtures	mixture	NOUN
admet-1317	55	30	as	as	SCONJ
admet-1317	55	31	illustrated	illustrate	VERB
admet-1317	55	32	in	in	ADP
admet-1317	55	33	table	table	NOUN
admet-1317	55	34	1	1	NUM
admet-1317	55	35	.	.	PUNCT
admet-1317	56	1	the	the	DET
admet-1317	56	2	mixtures	mixture	NOUN
admet-1317	56	3	were	be	AUX
admet-1317	56	4	then	then	ADV
admet-1317	56	5	stirred	stir	VERB
admet-1317	56	6	for	for	ADP
admet-1317	56	7	15	15	NUM
admet-1317	56	8	minutes	minute	NOUN
admet-1317	56	9	using	use	VERB
admet-1317	56	10	a	a	DET
admet-1317	56	11	magnetic	magnetic	ADJ
admet-1317	56	12	stirrer	stirrer	NOUN
admet-1317	56	13	at	at	ADP
admet-1317	56	14	600	600	NUM
admet-1317	56	15	rpm	rpm	NOUN
admet-1317	56	16	and	and	CCONJ
admet-1317	56	17	left	leave	VERB
admet-1317	56	18	to	to	PART
admet-1317	56	19	settle	settle	VERB
admet-1317	56	20	overnight	overnight	ADV
admet-1317	56	21	to	to	PART
admet-1317	56	22	remove	remove	VERB
admet-1317	56	23	any	any	DET
admet-1317	56	24	bubbles	bubble	NOUN
admet-1317	56	25	formed	form	VERB
admet-1317	56	26	.	.	PUNCT
admet-1317	57	1	afterward	afterward	ADV
admet-1317	57	2	,	,	PUNCT
admet-1317	57	3	100	100	NUM
admet-1317	57	4	µl	µl	ADP
admet-1317	57	5	of	of	ADP
admet-1317	57	6	each	each	DET
admet-1317	57	7	polymeric	polymeric	ADJ
admet-1317	57	8	formulation	formulation	NOUN
admet-1317	57	9	mixture	mixture	NOUN
admet-1317	57	10	containing	contain	VERB
admet-1317	57	11	50	50	NUM
admet-1317	57	12	µg	µg	NOUN
admet-1317	57	13	of	of	ADP
admet-1317	57	14	lt-4	lt-4	NOUN
admet-1317	57	15	as	as	SCONJ
admet-1317	57	16	an	an	DET
admet-1317	57	17	active	active	ADJ
admet-1317	57	18	pharmaceutical	pharmaceutical	ADJ
admet-1317	57	19	ingredient	ingredient	NOUN
admet-1317	57	20	was	be	AUX
admet-1317	57	21	poured	pour	VERB
admet-1317	57	22	into	into	ADP
admet-1317	57	23	mn	mn	PROPN
admet-1317	57	24	moulds	mould	NOUN
admet-1317	57	25	(	(	PUNCT
admet-1317	57	26	pdms	pdms	NOUN
admet-1317	57	27	mould	mould	NOUN
admet-1317	57	28	consisting	consist	VERB
admet-1317	57	29	of	of	ADP
admet-1317	57	30	10	10	NUM
admet-1317	57	31	×	×	NOUN
admet-1317	57	32	10	10	NUM
admet-1317	57	33	array	array	NOUN
admet-1317	57	34	on	on	ADP
admet-1317	57	35	a	a	DET
admet-1317	57	36	0.64	0.64	NUM
admet-1317	57	37	cm²	cm²	NOUN
admet-1317	57	38	area	area	NOUN
admet-1317	57	39	with	with	ADP
admet-1317	57	40	500	500	NUM
admet-1317	57	41	µm	µm	NOUN
admet-1317	57	42	needle	needle	NOUN
admet-1317	57	43	height	height	NOUN
admet-1317	57	44	,	,	PUNCT
admet-1317	57	45	300	300	NUM
admet-1317	57	46	µm	µm	ADP
admet-1317	57	47	needle	needle	NOUN
admet-1317	57	48	base	base	NOUN
admet-1317	57	49	and	and	CCONJ
admet-1317	57	50	500	500	NUM
admet-1317	57	51	µm	µm	ADP
admet-1317	57	52	interspacing	interspacing	NOUN
admet-1317	57	53	)	)	PUNCT
admet-1317	57	54	.	.	PUNCT
admet-1317	58	1	the	the	DET
admet-1317	58	2	mn	mn	PROPN
admet-1317	58	3	moulds	mould	NOUN
admet-1317	58	4	were	be	AUX
admet-1317	58	5	subjected	subject	VERB
admet-1317	58	6	to	to	ADP
admet-1317	58	7	centrifugation	centrifugation	NOUN
admet-1317	58	8	for	for	ADP
admet-1317	58	9	40	40	NUM
admet-1317	58	10	minutes	minute	NOUN
admet-1317	58	11	for	for	ADP
admet-1317	58	12	two	two	NUM
admet-1317	58	13	rounds	round	NOUN
admet-1317	58	14	(	(	PUNCT
admet-1317	58	15	2	2	NUM
admet-1317	58	16	х	х	PROPN
admet-1317	58	17	40	40	NUM
admet-1317	58	18	min	min	NOUN
admet-1317	58	19	.	.	PROPN
admet-1317	58	20	)	)	PUNCT
admet-1317	58	21	to	to	PART
admet-1317	58	22	ensure	ensure	VERB
admet-1317	58	23	the	the	DET
admet-1317	58	24	whole	whole	ADJ
admet-1317	58	25	volume	volume	NOUN
admet-1317	58	26	of	of	ADP
admet-1317	58	27	polymeric	polymeric	ADJ
admet-1317	58	28	mixture	mixture	NOUN
admet-1317	58	29	has	have	AUX
admet-1317	58	30	entered	enter	VERB
admet-1317	58	31	microcavities	microcavitie	NOUN
admet-1317	58	32	of	of	ADP
admet-1317	58	33	the	the	DET
admet-1317	58	34	mould	mould	NOUN
admet-1317	58	35	.	.	PUNCT
admet-1317	59	1	during	during	ADP
admet-1317	59	2	the	the	DET
admet-1317	59	3	centrifugation	centrifugation	NOUN
admet-1317	59	4	process	process	NOUN
admet-1317	59	5	,	,	PUNCT
admet-1317	59	6	the	the	DET
admet-1317	59	7	mn	mn	PROPN
admet-1317	59	8	moulds	mould	NOUN
admet-1317	59	9	were	be	AUX
admet-1317	59	10	covered	cover	VERB
admet-1317	59	11	with	with	ADP
admet-1317	59	12	silicon	silicon	NOUN
admet-1317	59	13	caps	cap	NOUN
admet-1317	59	14	and	and	CCONJ
admet-1317	59	15	adhesive	adhesive	ADJ
admet-1317	59	16	tape	tape	NOUN
admet-1317	59	17	to	to	PART
admet-1317	59	18	prevent	prevent	VERB
admet-1317	59	19	the	the	DET
admet-1317	59	20	solution	solution	NOUN
admet-1317	59	21	spill	spill	VERB
admet-1317	59	22	out	out	ADP
admet-1317	59	23	from	from	ADP
admet-1317	59	24	the	the	DET
admet-1317	59	25	mould	mould	NOUN
admet-1317	59	26	.	.	PUNCT
admet-1317	60	1	the	the	DET
admet-1317	60	2	moulded	mould	VERB
admet-1317	60	3	mixture	mixture	NOUN
admet-1317	60	4	was	be	AUX
admet-1317	60	5	kept	keep	VERB
admet-1317	60	6	to	to	PART
admet-1317	60	7	dry	dry	VERB
admet-1317	60	8	for	for	ADP
admet-1317	60	9	24	24	NUM
admet-1317	60	10	hours	hour	NOUN
admet-1317	60	11	in	in	ADP
admet-1317	60	12	a	a	DET
admet-1317	60	13	desiccator	desiccator	NOUN
admet-1317	60	14	at	at	ADP
admet-1317	60	15	ambient	ambient	ADJ
admet-1317	60	16	conditions	condition	NOUN
admet-1317	60	17	protected	protect	VERB
admet-1317	60	18	from	from	ADP
admet-1317	60	19	light	light	NOUN
admet-1317	60	20	.	.	PUNCT
admet-1317	61	1	the	the	DET
admet-1317	61	2	microneedle	microneedle	NOUN
admet-1317	61	3	arrays	array	VERB
admet-1317	61	4	were	be	AUX
admet-1317	61	5	then	then	ADV
admet-1317	61	6	removed	remove	VERB
admet-1317	61	7	from	from	ADP
admet-1317	61	8	the	the	DET
admet-1317	61	9	mould	mould	NOUN
admet-1317	61	10	and	and	CCONJ
admet-1317	61	11	examined	examine	VERB
admet-1317	61	12	using	use	VERB
admet-1317	61	13	a	a	DET
admet-1317	61	14	digital	digital	ADJ
admet-1317	61	15	microscope	microscope	NOUN
admet-1317	61	16	.	.	PUNCT
admet-1317	62	1	mns	mns	PROPN
admet-1317	62	2	were	be	AUX
admet-1317	62	3	stored	store	VERB
admet-1317	62	4	wrapped	wrap	VERB
admet-1317	62	5	with	with	ADP
admet-1317	62	6	aluminium	aluminium	NOUN
admet-1317	62	7	foil	foil	NOUN
admet-1317	62	8	in	in	ADP
admet-1317	62	9	a	a	DET
admet-1317	62	10	desiccator	desiccator	NOUN
admet-1317	62	11	until	until	ADP
admet-1317	62	12	use	use	NOUN
admet-1317	62	13	.	.	PUNCT
admet-1317	63	1	table	table	NOUN
admet-1317	63	2	1	1	NUM
admet-1317	63	3	.	.	PUNCT
admet-1317	64	1	composition	composition	NOUN
admet-1317	64	2	of	of	ADP
admet-1317	64	3	polymeric	polymeric	ADJ
admet-1317	64	4	dissolving	dissolving	NOUN
admet-1317	64	5	microneedle	microneedle	NOUN
admet-1317	64	6	formulations	formulation	NOUN
admet-1317	64	7	.	.	PUNCT
admet-1317	65	1	formulation	formulation	NOUN
admet-1317	65	2	code	code	NOUN
admet-1317	65	3	lt-4	lt-4	NOUN
admet-1317	66	1	(	(	PUNCT
admet-1317	66	2	%	%	INTJ
admet-1317	66	3	w	w	NOUN
admet-1317	66	4	/	/	SYM
admet-1317	66	5	v	v	NOUN
admet-1317	66	6	)	)	PUNCT
admet-1317	66	7	ha	ha	INTJ
admet-1317	66	8	(	(	PUNCT
admet-1317	66	9	%	%	INTJ
admet-1317	66	10	w	w	PROPN
admet-1317	66	11	/	/	SYM
admet-1317	66	12	v	v	NOUN
admet-1317	66	13	)	)	PUNCT
admet-1317	66	14	tween	tween	NOUN
admet-1317	66	15	80	80	NUM
admet-1317	66	16	(	(	PUNCT
admet-1317	66	17	%	%	NOUN
admet-1317	66	18	v	v	ADP
admet-1317	66	19	/	/	SYM
admet-1317	66	20	v	v	NOUN
admet-1317	66	21	)	)	PUNCT
admet-1317	66	22	dw	dw	NOUN
admet-1317	66	23	(	(	PUNCT
admet-1317	66	24	%	%	INTJ
admet-1317	66	25	v	v	ADP
admet-1317	66	26	/	/	SYM
admet-1317	66	27	v	v	NOUN
admet-1317	66	28	)	)	PUNCT
admet-1317	66	29	up	up	ADP
admet-1317	66	30	to	to	PART
admet-1317	66	31	f1	f1	VERB
admet-1317	66	32	0.05	0.05	NUM
admet-1317	66	33	5	5	NUM
admet-1317	66	34	1	1	NUM
admet-1317	66	35	100	100	NUM
admet-1317	66	36	f2	f2	PROPN
admet-1317	66	37	0.05	0.05	NUM
admet-1317	66	38	5	5	NUM
admet-1317	66	39	2	2	NUM
admet-1317	66	40	100	100	NUM
admet-1317	66	41	f3	f3	NOUN
admet-1317	66	42	0.05	0.05	NUM
admet-1317	66	43	10	10	NUM
admet-1317	66	44	1	1	NUM
admet-1317	66	45	100	100	NUM
admet-1317	66	46	f4	f4	NUM
admet-1317	66	47	0.05	0.05	NUM
admet-1317	66	48	15	15	NUM
admet-1317	66	49	1	1	NUM
admet-1317	66	50	100	100	NUM
admet-1317	66	51	f5	f5	NOUN
admet-1317	66	52	0.05	0.05	NUM
admet-1317	66	53	20	20	NUM
admet-1317	66	54	1	1	NUM
admet-1317	66	55	100	100	NUM
admet-1317	66	56	f6	f6	NUM
admet-1317	66	57	0.05	0.05	NUM
admet-1317	66	58	25	25	NUM
admet-1317	66	59	1	1	NUM
admet-1317	66	60	100	100	NUM
admet-1317	66	61	f7	f7	PROPN
admet-1317	66	62	0.05	0.05	NUM
admet-1317	66	63	30	30	NUM
admet-1317	66	64	1	1	NUM
admet-1317	66	65	100	100	NUM
admet-1317	66	66	f8	f8	PROPN
admet-1317	66	67	0.05	0.05	NUM
admet-1317	66	68	35	35	NUM
admet-1317	66	69	1	1	NUM
admet-1317	66	70	100	100	NUM
admet-1317	66	71	f9	f9	PROPN
admet-1317	66	72	0.05	0.05	NUM
admet-1317	66	73	40	40	NUM
admet-1317	66	74	1	1	NUM
admet-1317	66	75	100	100	NUM
admet-1317	66	76	f10	f10	NOUN
admet-1317	66	77	0.05	0.05	NUM
admet-1317	66	78	45	45	NUM
admet-1317	66	79	1	1	NUM
admet-1317	66	80	100	100	NUM
admet-1317	66	81	f11	f11	NOUN
admet-1317	66	82	0.05	0.05	NUM
admet-1317	66	83	50	50	NUM
admet-1317	66	84	1	1	NUM
admet-1317	66	85	100	100	NUM
admet-1317	66	86	f12	f12	NOUN
admet-1317	66	87	0.05	0.05	NUM
admet-1317	66	88	55	55	NUM
admet-1317	66	89	1	1	NUM
admet-1317	66	90	100	100	NUM
admet-1317	66	91	f13	f13	NUM
admet-1317	66	92	0.05	0.05	NUM
admet-1317	66	93	60	60	NUM
admet-1317	66	94	1	1	NUM
admet-1317	66	95	100	100	NUM
admet-1317	66	96	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	NOUN
admet-1317	66	97	r.f	r.f	PROPN
admet-1317	66	98	.	.	PROPN
admet-1317	66	99	ghazi	ghazi	PROPN
admet-1317	66	100	and	and	CCONJ
admet-1317	66	101	m.h	m.h	PROPN
admet-1317	66	102	.	.	PROPN
admet-1317	66	103	al	al	PROPN
admet-1317	66	104	-	-	PUNCT
admet-1317	66	105	mayahy	mayahy	PROPN
admet-1317	66	106	admet	admet	PROPN
admet-1317	66	107	&	&	CCONJ
admet-1317	66	108	dmpk	dmpk	PROPN
admet-1317	66	109	10(3	10(3	NUM
admet-1317	66	110	)	)	PUNCT
admet-1317	66	111	(	(	PUNCT
admet-1317	66	112	2022	2022	NUM
admet-1317	66	113	)	)	PUNCT
admet-1317	66	114	213	213	NUM
admet-1317	66	115	-	-	SYM
admet-1317	66	116	230	230	NUM
admet-1317	66	117	216	216	NUM
admet-1317	66	118	characterisation	characterisation	NOUN
admet-1317	66	119	of	of	ADP
admet-1317	66	120	hyaluronic	hyaluronic	ADJ
admet-1317	66	121	acid	acid	NOUN
admet-1317	66	122	microneedle	microneedle	NOUN
admet-1317	66	123	arrays	array	VERB
admet-1317	66	124	assessment	assessment	NOUN
admet-1317	66	125	of	of	ADP
admet-1317	66	126	the	the	DET
admet-1317	66	127	mechanical	mechanical	ADJ
admet-1317	66	128	properties	property	NOUN
admet-1317	66	129	of	of	ADP
admet-1317	66	130	ha	ha	INTJ
admet-1317	66	131	microneedle	microneedle	PROPN
admet-1317	66	132	arrays	array	VERB
admet-1317	66	133	.	.	PUNCT
admet-1317	67	1	a	a	PRON
admet-1317	67	2	ta	ta	PROPN
admet-1317	67	3	-	-	PUNCT
admet-1317	67	4	xt2	xt2	PROPN
admet-1317	67	5	texture	texture	NOUN
admet-1317	67	6	analyser	analyser	NOUN
admet-1317	67	7	(	(	PUNCT
admet-1317	67	8	stable	stable	ADJ
admet-1317	67	9	microsystems	microsystem	NOUN
admet-1317	67	10	,	,	PUNCT
admet-1317	67	11	copley	copley	NOUN
admet-1317	67	12	,	,	PUNCT
admet-1317	67	13	uk	uk	PROPN
admet-1317	67	14	)	)	PUNCT
admet-1317	67	15	was	be	AUX
admet-1317	67	16	used	use	VERB
admet-1317	67	17	to	to	PART
admet-1317	67	18	test	test	VERB
admet-1317	67	19	mn	mn	PROPN
admet-1317	67	20	arrays	array	VERB
admet-1317	67	21	for	for	ADP
admet-1317	67	22	their	their	PRON
admet-1317	67	23	mechanical	mechanical	ADJ
admet-1317	67	24	strength	strength	NOUN
admet-1317	67	25	.	.	PUNCT
admet-1317	68	1	in	in	ADP
admet-1317	68	2	brief	brief	NOUN
admet-1317	68	3	,	,	PUNCT
admet-1317	68	4	mn	mn	PROPN
admet-1317	68	5	arrays	array	VERB
admet-1317	68	6	were	be	AUX
admet-1317	68	7	mounted	mount	VERB
admet-1317	68	8	to	to	ADP
admet-1317	68	9	the	the	DET
admet-1317	68	10	texture	texture	NOUN
admet-1317	68	11	analyser	analyser	NOUN
admet-1317	68	12	's	's	PART
admet-1317	68	13	movable	movable	ADJ
admet-1317	68	14	probe	probe	NOUN
admet-1317	68	15	(	(	PUNCT
admet-1317	68	16	0.5	0.5	NUM
admet-1317	68	17	cm	cm	NOUN
admet-1317	68	18	in	in	ADP
admet-1317	68	19	length	length	NOUN
admet-1317	68	20	)	)	PUNCT
admet-1317	68	21	.	.	PUNCT
admet-1317	69	1	the	the	DET
admet-1317	69	2	probe	probe	NOUN
admet-1317	69	3	was	be	AUX
admet-1317	69	4	set	set	VERB
admet-1317	69	5	to	to	PART
admet-1317	69	6	move	move	VERB
admet-1317	69	7	downward	downward	ADV
admet-1317	69	8	at	at	ADP
admet-1317	69	9	a	a	DET
admet-1317	69	10	pre	pre	ADJ
admet-1317	69	11	-	-	ADJ
admet-1317	69	12	test	test	ADJ
admet-1317	69	13	speed	speed	NOUN
admet-1317	69	14	of	of	ADP
admet-1317	69	15	1	1	NUM
admet-1317	69	16	mm	mm	PROPN
admet-1317	69	17	/	/	SYM
admet-1317	69	18	s	s	PROPN
admet-1317	69	19	,	,	PUNCT
admet-1317	69	20	test	test	NOUN
admet-1317	69	21	speed	speed	NOUN
admet-1317	69	22	of	of	ADP
admet-1317	69	23	0.5	0.5	NUM
admet-1317	69	24	mm	mm	NOUN
admet-1317	69	25	/	/	SYM
admet-1317	69	26	s	s	PROPN
admet-1317	69	27	and	and	CCONJ
admet-1317	69	28	post	post	ADJ
admet-1317	69	29	-	-	ADJ
admet-1317	69	30	test	test	ADJ
admet-1317	69	31	speed	speed	NOUN
admet-1317	69	32	of	of	ADP
admet-1317	69	33	10	10	NUM
admet-1317	69	34	mm	mm	NOUN
admet-1317	69	35	/	/	SYM
admet-1317	69	36	s.	s.	PROPN
admet-1317	69	37	a	a	DET
admet-1317	69	38	force	force	NOUN
admet-1317	69	39	of	of	ADP
admet-1317	69	40	32	32	NUM
admet-1317	69	41	n	n	NOUN
admet-1317	69	42	per	per	ADP
admet-1317	69	43	array	array	NOUN
admet-1317	69	44	was	be	AUX
admet-1317	69	45	applied	apply	VERB
admet-1317	69	46	for	for	ADP
admet-1317	69	47	30	30	NUM
admet-1317	69	48	seconds	second	NOUN
admet-1317	69	49	to	to	PART
admet-1317	69	50	press	press	VERB
admet-1317	69	51	the	the	DET
admet-1317	69	52	mn	mn	PROPN
admet-1317	69	53	arrays	array	VERB
admet-1317	69	54	down	down	ADP
admet-1317	69	55	towards	towards	ADP
admet-1317	69	56	a	a	DET
admet-1317	69	57	flat	flat	ADJ
admet-1317	69	58	metal	metal	NOUN
admet-1317	69	59	block	block	NOUN
admet-1317	69	60	of	of	ADP
admet-1317	69	61	9.2	9.2	NUM
admet-1317	69	62	×	×	NOUN
admet-1317	69	63	5.2	5.2	NUM
admet-1317	69	64	cm	cm	NOUN
admet-1317	69	65	dimensions	dimension	NOUN
admet-1317	70	1	[	[	X
admet-1317	70	2	18	18	NUM
admet-1317	70	3	]	]	PUNCT
admet-1317	70	4	.	.	PUNCT
admet-1317	71	1	a	a	DET
admet-1317	71	2	digital	digital	ADJ
admet-1317	71	3	microscope	microscope	NOUN
admet-1317	71	4	(	(	PUNCT
admet-1317	71	5	rohs	rohs	PROPN
admet-1317	71	6	,	,	PUNCT
admet-1317	71	7	china	china	PROPN
admet-1317	71	8	)	)	PUNCT
admet-1317	71	9	was	be	AUX
admet-1317	71	10	utilised	utilise	VERB
admet-1317	71	11	to	to	PART
admet-1317	71	12	observe	observe	VERB
admet-1317	71	13	the	the	DET
admet-1317	71	14	mn	mn	PROPN
admet-1317	71	15	arrays	array	VERB
admet-1317	71	16	prior	prior	ADV
admet-1317	71	17	and	and	CCONJ
admet-1317	71	18	following	follow	VERB
admet-1317	71	19	the	the	DET
admet-1317	71	20	appliance	appliance	NOUN
admet-1317	71	21	of	of	ADP
admet-1317	71	22	the	the	DET
admet-1317	71	23	compression	compression	NOUN
admet-1317	71	24	load	load	NOUN
admet-1317	71	25	.	.	PUNCT
admet-1317	72	1	individual	individual	ADJ
admet-1317	72	2	mns	mns	PROPN
admet-1317	72	3	’	'	PUNCT
admet-1317	72	4	heights	height	NOUN
admet-1317	72	5	were	be	AUX
admet-1317	72	6	measured	measure	VERB
admet-1317	72	7	before	before	ADV
admet-1317	72	8	and	and	CCONJ
admet-1317	72	9	after	after	ADP
admet-1317	72	10	testing	testing	NOUN
admet-1317	72	11	using	use	VERB
admet-1317	72	12	the	the	DET
admet-1317	72	13	ruler	ruler	NOUN
admet-1317	72	14	feature	feature	NOUN
admet-1317	72	15	of	of	ADP
admet-1317	72	16	image	image	NOUN
admet-1317	72	17	j	j	PROPN
admet-1317	72	18	®	®	NOUN
admet-1317	72	19	software	software	NOUN
admet-1317	72	20	(	(	PUNCT
admet-1317	72	21	us	us	PROPN
admet-1317	72	22	national	national	PROPN
admet-1317	72	23	institutes	institutes	PROPN
admet-1317	72	24	of	of	ADP
admet-1317	72	25	health	health	NOUN
admet-1317	72	26	,	,	PUNCT
admet-1317	72	27	bethesda	bethesda	NOUN
admet-1317	72	28	,	,	PUNCT
admet-1317	72	29	maryland	maryland	PROPN
admet-1317	72	30	,	,	PUNCT
admet-1317	72	31	usa	usa	PROPN
admet-1317	72	32	)	)	PUNCT
admet-1317	72	33	in	in	ADP
admet-1317	72	34	order	order	NOUN
admet-1317	72	35	to	to	PART
admet-1317	72	36	determine	determine	VERB
admet-1317	72	37	the	the	DET
admet-1317	72	38	percent	percent	NOUN
admet-1317	72	39	height	height	NOUN
admet-1317	72	40	reduction	reduction	NOUN
admet-1317	72	41	using	use	VERB
admet-1317	72	42	equation	equation	NOUN
admet-1317	72	43	number	number	NOUN
admet-1317	72	44	(	(	PUNCT
admet-1317	72	45	1	1	NUM
admet-1317	72	46	)	)	PUNCT
admet-1317	73	1	[	[	X
admet-1317	73	2	21	21	NUM
admet-1317	73	3	]	]	PUNCT
admet-1317	73	4	:	:	PUNCT
admet-1317	73	5	%	%	NOUN
admet-1317	73	6	compression	compression	NOUN
admet-1317	73	7	=	=	SYM
admet-1317	73	8	hbc	hbc	PROPN
admet-1317	73	9	hac	hac	X
admet-1317	73	10	/	/	SYM
admet-1317	73	11	hbc*100	hbc*100	NOUN
admet-1317	73	12	.	.	PUNCT
admet-1317	74	1	(	(	PUNCT
admet-1317	74	2	1	1	X
admet-1317	74	3	)	)	PUNCT
admet-1317	74	4	hbc	hbc	NOUN
admet-1317	74	5	is	be	AUX
admet-1317	74	6	the	the	DET
admet-1317	74	7	height	height	NOUN
admet-1317	74	8	prior	prior	ADV
admet-1317	74	9	to	to	ADP
admet-1317	74	10	compression	compression	NOUN
admet-1317	74	11	and	and	CCONJ
admet-1317	74	12	hac	hac	X
admet-1317	74	13	is	be	AUX
admet-1317	74	14	the	the	DET
admet-1317	74	15	height	height	NOUN
admet-1317	74	16	following	follow	VERB
admet-1317	74	17	compression	compression	NOUN
admet-1317	74	18	.	.	PUNCT
admet-1317	75	1	in	in	ADP
admet-1317	75	2	vitro	vitro	X
admet-1317	75	3	drug	drug	NOUN
admet-1317	75	4	release	release	NOUN
admet-1317	75	5	study	study	NOUN
admet-1317	75	6	.	.	PUNCT
admet-1317	76	1	in	in	ADP
admet-1317	76	2	vitro	vitro	X
admet-1317	76	3	drug	drug	NOUN
admet-1317	76	4	release	release	NOUN
admet-1317	76	5	of	of	ADP
admet-1317	76	6	lt-4	lt-4	NOUN
admet-1317	76	7	sodium	sodium	NOUN
admet-1317	76	8	was	be	AUX
admet-1317	76	9	performed	perform	VERB
admet-1317	76	10	for	for	ADP
admet-1317	76	11	mns	mns	PROPN
admet-1317	76	12	formulations	formulation	NOUN
admet-1317	76	13	(	(	PUNCT
admet-1317	76	14	f8	f8	PROPN
admet-1317	76	15	,	,	PUNCT
admet-1317	76	16	f9	f9	PROPN
admet-1317	76	17	,	,	PUNCT
admet-1317	76	18	f10	f10	NOUN
admet-1317	76	19	and	and	CCONJ
admet-1317	76	20	f11	f11	NUM
admet-1317	76	21	)	)	PUNCT
admet-1317	76	22	using	use	VERB
admet-1317	76	23	franz	franz	NOUN
admet-1317	76	24	diffusion	diffusion	NOUN
admet-1317	76	25	cells	cell	NOUN
admet-1317	76	26	with	with	ADP
admet-1317	76	27	an	an	DET
admet-1317	76	28	exposed	expose	VERB
admet-1317	76	29	surface	surface	NOUN
admet-1317	76	30	area	area	NOUN
admet-1317	76	31	of	of	ADP
admet-1317	76	32	0.785	0.785	NUM
admet-1317	76	33	cm²	cm²	NOUN
admet-1317	76	34	.	.	PUNCT
admet-1317	77	1	mn	mn	PROPN
admet-1317	77	2	arrays	array	VERB
admet-1317	77	3	were	be	AUX
admet-1317	77	4	fixed	fix	VERB
admet-1317	77	5	on	on	ADP
admet-1317	77	6	a	a	DET
admet-1317	77	7	small	small	ADJ
admet-1317	77	8	sieve	sieve	NOUN
admet-1317	77	9	and	and	CCONJ
admet-1317	77	10	mounted	mount	VERB
admet-1317	77	11	on	on	ADP
admet-1317	77	12	franz	franz	NOUN
admet-1317	77	13	cells	cell	NOUN
admet-1317	77	14	with	with	ADP
admet-1317	77	15	the	the	DET
admet-1317	77	16	needles	needle	NOUN
admet-1317	77	17	facing	face	VERB
admet-1317	77	18	downwards	downward	NOUN
admet-1317	77	19	.	.	PUNCT
admet-1317	78	1	the	the	DET
admet-1317	78	2	receptor	receptor	NOUN
admet-1317	78	3	chamber	chamber	NOUN
admet-1317	78	4	was	be	AUX
admet-1317	78	5	filled	fill	VERB
admet-1317	78	6	with	with	ADP
admet-1317	78	7	10	10	NUM
admet-1317	78	8	ml	ml	NOUN
admet-1317	78	9	of	of	ADP
admet-1317	78	10	the	the	DET
admet-1317	78	11	solvent	solvent	NOUN
admet-1317	78	12	mixture	mixture	NOUN
admet-1317	78	13	containing	contain	VERB
admet-1317	78	14	ethanol	ethanol	NOUN
admet-1317	78	15	(	(	PUNCT
admet-1317	78	16	25	25	NUM
admet-1317	78	17	%	%	NOUN
admet-1317	78	18	v	v	ADP
admet-1317	78	19	/	/	SYM
admet-1317	78	20	v	v	NOUN
admet-1317	78	21	)	)	PUNCT
admet-1317	78	22	and	and	CCONJ
admet-1317	78	23	dw	dw	X
admet-1317	78	24	(	(	PUNCT
admet-1317	78	25	75	75	NUM
admet-1317	78	26	%	%	NOUN
admet-1317	78	27	v	v	ADP
admet-1317	78	28	/	/	SYM
admet-1317	78	29	v	v	NOUN
admet-1317	78	30	)	)	PUNCT
admet-1317	78	31	as	as	ADP
admet-1317	78	32	a	a	DET
admet-1317	78	33	receptor	receptor	NOUN
admet-1317	78	34	fluid	fluid	NOUN
admet-1317	78	35	.	.	PUNCT
admet-1317	79	1	franz	franz	PROPN
admet-1317	79	2	cells	cell	NOUN
admet-1317	79	3	were	be	AUX
admet-1317	79	4	then	then	ADV
admet-1317	79	5	placed	place	VERB
admet-1317	79	6	in	in	ADP
admet-1317	79	7	diffusion	diffusion	NOUN
admet-1317	79	8	cells	cell	NOUN
admet-1317	79	9	apparatus	apparatus	NOUN
admet-1317	79	10	(	(	PUNCT
admet-1317	79	11	stirring	stir	VERB
admet-1317	79	12	water	water	NOUN
admet-1317	79	13	bath	bath	NOUN
admet-1317	79	14	,	,	PUNCT
admet-1317	79	15	orchid	orchid	NOUN
admet-1317	79	16	scientific	scientific	ADJ
admet-1317	79	17	,	,	PUNCT
admet-1317	79	18	india	india	PROPN
admet-1317	79	19	)	)	PUNCT
admet-1317	79	20	at	at	ADP
admet-1317	79	21	37	37	NUM
admet-1317	79	22	°	°	NOUN
admet-1317	79	23	c	c	NOUN
admet-1317	79	24	.	.	PUNCT
admet-1317	80	1	the	the	DET
admet-1317	80	2	receptor	receptor	NOUN
admet-1317	80	3	fluid	fluid	NOUN
admet-1317	80	4	was	be	AUX
admet-1317	80	5	stirred	stir	VERB
admet-1317	80	6	continuously	continuously	ADV
admet-1317	80	7	by	by	ADP
admet-1317	80	8	a	a	DET
admet-1317	80	9	small	small	ADJ
admet-1317	80	10	teflon	teflon	NOUN
admet-1317	80	11	-	-	PUNCT
admet-1317	80	12	coated	coat	VERB
admet-1317	80	13	magnetic	magnetic	ADJ
admet-1317	80	14	bar	bar	NOUN
admet-1317	80	15	at	at	ADP
admet-1317	80	16	400	400	NUM
admet-1317	80	17	rpm	rpm	NOUN
admet-1317	80	18	.	.	PUNCT
admet-1317	81	1	sink	sink	NOUN
admet-1317	81	2	condition	condition	NOUN
admet-1317	81	3	was	be	AUX
admet-1317	81	4	maintained	maintain	VERB
admet-1317	81	5	;	;	PUNCT
admet-1317	81	6	since	since	SCONJ
admet-1317	81	7	the	the	DET
admet-1317	81	8	samples	sample	NOUN
admet-1317	81	9	of	of	ADP
admet-1317	81	10	1	1	NUM
admet-1317	81	11	ml	ml	NOUN
admet-1317	81	12	were	be	AUX
admet-1317	81	13	removed	remove	VERB
admet-1317	81	14	from	from	ADP
admet-1317	81	15	the	the	DET
admet-1317	81	16	receptor	receptor	NOUN
admet-1317	81	17	,	,	PUNCT
admet-1317	81	18	fluid	fluid	NOUN
admet-1317	81	19	was	be	AUX
admet-1317	81	20	recovered	recover	VERB
admet-1317	81	21	with	with	ADP
admet-1317	81	22	the	the	DET
admet-1317	81	23	same	same	ADJ
admet-1317	81	24	volume	volume	NOUN
admet-1317	81	25	of	of	ADP
admet-1317	81	26	the	the	DET
admet-1317	81	27	fresh	fresh	ADJ
admet-1317	81	28	pre	pre	ADJ
admet-1317	81	29	-	-	ADJ
admet-1317	81	30	heated	heated	ADJ
admet-1317	81	31	solvent	solvent	NOUN
admet-1317	81	32	mixture	mixture	NOUN
admet-1317	81	33	.	.	PUNCT
admet-1317	82	1	samples	sample	NOUN
admet-1317	82	2	withdrawn	withdraw	VERB
admet-1317	82	3	were	be	AUX
admet-1317	82	4	analyzed	analyze	VERB
admet-1317	82	5	for	for	ADP
admet-1317	82	6	lt-4	lt-4	NOUN
admet-1317	82	7	sodium	sodium	NOUN
admet-1317	82	8	content	content	NOUN
admet-1317	82	9	by	by	ADP
admet-1317	82	10	uv	uv	NOUN
admet-1317	82	11	-	-	PUNCT
admet-1317	82	12	spectrophotometer	spectrophotometer	NOUN
admet-1317	82	13	to	to	PART
admet-1317	82	14	determine	determine	VERB
admet-1317	82	15	the	the	DET
admet-1317	82	16	percentage	percentage	NOUN
admet-1317	82	17	of	of	ADP
admet-1317	82	18	drug	drug	NOUN
admet-1317	82	19	released	release	VERB
admet-1317	82	20	[	[	PUNCT
admet-1317	82	21	22	22	NUM
admet-1317	82	22	]	]	PUNCT
admet-1317	82	23	.	.	PUNCT
admet-1317	83	1	detection	detection	NOUN
admet-1317	83	2	of	of	ADP
admet-1317	83	3	microneedles	microneedle	NOUN
admet-1317	83	4	insertion	insertion	NOUN
admet-1317	83	5	ability	ability	NOUN
admet-1317	83	6	using	use	VERB
admet-1317	83	7	parafilm	parafilm	PROPN
admet-1317	83	8	m	m	PROPN
admet-1317	83	9	®	®	PROPN
admet-1317	83	10	.	.	PUNCT
admet-1317	84	1	in	in	ADP
admet-1317	84	2	their	their	PRON
admet-1317	84	3	latest	late	ADJ
admet-1317	84	4	work	work	NOUN
admet-1317	84	5	(	(	PUNCT
admet-1317	84	6	larraneta	larraneta	INTJ
admet-1317	84	7	et	et	PROPN
admet-1317	84	8	al	al	PROPN
admet-1317	84	9	.	.	PROPN
admet-1317	84	10	,	,	PUNCT
admet-1317	84	11	2014	2014	NUM
admet-1317	84	12	)	)	PUNCT
admet-1317	84	13	,	,	PUNCT
admet-1317	84	14	they	they	PRON
admet-1317	84	15	demonstrated	demonstrate	VERB
admet-1317	84	16	a	a	DET
admet-1317	84	17	great	great	ADJ
admet-1317	84	18	resemblance	resemblance	NOUN
admet-1317	84	19	between	between	ADP
admet-1317	84	20	parafilm	parafilm	NOUN
admet-1317	84	21	m	m	PROPN
admet-1317	84	22	®	®	PROPN
admet-1317	84	23	(	(	PUNCT
admet-1317	84	24	pf	pf	NOUN
admet-1317	84	25	)	)	PUNCT
admet-1317	84	26	layers	layer	NOUN
admet-1317	84	27	and	and	CCONJ
admet-1317	84	28	porcine	porcine	NOUN
admet-1317	84	29	skin	skin	NOUN
admet-1317	84	30	,	,	PUNCT
admet-1317	84	31	suggesting	suggest	VERB
admet-1317	84	32	that	that	SCONJ
admet-1317	84	33	simple	simple	ADJ
admet-1317	84	34	insertion	insertion	NOUN
admet-1317	84	35	tests	test	VERB
admet-1317	84	36	on	on	ADP
admet-1317	84	37	pf	pf	PROPN
admet-1317	84	38	layers	layer	NOUN
admet-1317	84	39	may	may	AUX
admet-1317	84	40	be	be	AUX
admet-1317	84	41	performed	perform	VERB
admet-1317	84	42	reliably	reliably	ADV
admet-1317	84	43	.	.	PUNCT
admet-1317	85	1	the	the	DET
admet-1317	85	2	film	film	NOUN
admet-1317	85	3	is	be	AUX
admet-1317	85	4	folded	fold	VERB
admet-1317	85	5	into	into	ADP
admet-1317	85	6	eight	eight	NUM
admet-1317	85	7	layers	layer	NOUN
admet-1317	85	8	to	to	PART
admet-1317	85	9	achieve	achieve	VERB
admet-1317	85	10	a	a	DET
admet-1317	85	11	thickness	thickness	NOUN
admet-1317	85	12	of	of	ADP
admet-1317	85	13	approximately	approximately	ADV
admet-1317	85	14	1	1	NUM
admet-1317	85	15	mm	mm	NOUN
admet-1317	85	16	,	,	PUNCT
admet-1317	85	17	with	with	ADP
admet-1317	85	18	one	one	NUM
admet-1317	85	19	layer	layer	NOUN
admet-1317	85	20	being	be	AUX
admet-1317	85	21	127	127	NUM
admet-1317	85	22	µm	µm	NOUN
admet-1317	85	23	.	.	PUNCT
admet-1317	86	1	the	the	DET
admet-1317	86	2	mn	mn	PROPN
admet-1317	86	3	array	array	NOUN
admet-1317	86	4	was	be	AUX
admet-1317	86	5	inserted	insert	VERB
admet-1317	86	6	into	into	ADP
admet-1317	86	7	the	the	DET
admet-1317	86	8	eight	eight	NUM
admet-1317	86	9	membrane	membrane	NOUN
admet-1317	86	10	layers	layer	NOUN
admet-1317	86	11	using	use	VERB
admet-1317	86	12	a	a	DET
admet-1317	86	13	force	force	NOUN
admet-1317	86	14	of	of	ADP
admet-1317	86	15	(	(	PUNCT
admet-1317	86	16	32	32	NUM
admet-1317	86	17	n	n	CCONJ
admet-1317	86	18	)	)	PUNCT
admet-1317	86	19	generated	generate	VERB
admet-1317	86	20	by	by	ADP
admet-1317	86	21	the	the	DET
admet-1317	86	22	texture	texture	NOUN
admet-1317	86	23	analyser	analyser	NOUN
admet-1317	86	24	instrument	instrument	NOUN
admet-1317	86	25	.	.	PUNCT
admet-1317	87	1	following	follow	VERB
admet-1317	87	2	insertion	insertion	NOUN
admet-1317	87	3	,	,	PUNCT
admet-1317	87	4	the	the	DET
admet-1317	87	5	mn	mn	PROPN
admet-1317	87	6	array	array	NOUN
admet-1317	87	7	was	be	AUX
admet-1317	87	8	withdrawn	withdraw	VERB
admet-1317	87	9	from	from	ADP
admet-1317	87	10	the	the	DET
admet-1317	87	11	workbench	workbench	NOUN
admet-1317	87	12	and	and	CCONJ
admet-1317	87	13	the	the	DET
admet-1317	87	14	pf	pf	PROPN
admet-1317	87	15	layers	layer	NOUN
admet-1317	87	16	were	be	AUX
admet-1317	87	17	unfolded	unfold	VERB
admet-1317	87	18	,	,	PUNCT
admet-1317	87	19	allowing	allow	VERB
admet-1317	87	20	the	the	DET
admet-1317	87	21	number	number	NOUN
admet-1317	87	22	of	of	ADP
admet-1317	87	23	holes	hole	NOUN
admet-1317	87	24	remaining	remain	VERB
admet-1317	87	25	in	in	ADP
admet-1317	87	26	each	each	DET
admet-1317	87	27	layer	layer	NOUN
admet-1317	87	28	to	to	PART
admet-1317	87	29	be	be	AUX
admet-1317	87	30	determined	determine	VERB
admet-1317	87	31	(	(	PUNCT
admet-1317	87	32	using	use	VERB
admet-1317	87	33	a	a	DET
admet-1317	87	34	digital	digital	ADJ
admet-1317	87	35	microscope	microscope	NOUN
admet-1317	87	36	)	)	PUNCT
admet-1317	87	37	.	.	PUNCT
admet-1317	88	1	the	the	DET
admet-1317	88	2	thickness	thickness	NOUN
admet-1317	88	3	of	of	ADP
admet-1317	88	4	one	one	NUM
admet-1317	88	5	layer	layer	NOUN
admet-1317	88	6	being	be	AUX
admet-1317	88	7	127	127	NUM
admet-1317	88	8	µm	µm	ADP
admet-1317	88	9	±	±	NUM
admet-1317	88	10	7	7	NUM
admet-1317	88	11	µm	µm	NOUN
admet-1317	88	12	,	,	PUNCT
admet-1317	88	13	hence	hence	ADV
admet-1317	88	14	the	the	DET
admet-1317	88	15	insertion	insertion	NOUN
admet-1317	88	16	depth	depth	NOUN
admet-1317	88	17	can	can	AUX
admet-1317	88	18	be	be	AUX
admet-1317	88	19	deduced	deduce	VERB
admet-1317	88	20	[	[	X
admet-1317	88	21	23	23	NUM
admet-1317	88	22	]	]	PUNCT
admet-1317	88	23	.	.	PUNCT
admet-1317	89	1	insertion	insertion	NOUN
admet-1317	89	2	of	of	ADP
admet-1317	89	3	microneedle	microneedle	NOUN
admet-1317	89	4	arrays	array	VERB
admet-1317	89	5	into	into	ADP
admet-1317	89	6	excised	excise	VERB
admet-1317	89	7	human	human	ADJ
admet-1317	89	8	skin	skin	NOUN
admet-1317	89	9	.	.	PUNCT
admet-1317	90	1	to	to	PART
admet-1317	90	2	investigate	investigate	VERB
admet-1317	90	3	the	the	DET
admet-1317	90	4	skin	skin	NOUN
admet-1317	90	5	insertion	insertion	NOUN
admet-1317	90	6	ability	ability	NOUN
admet-1317	90	7	of	of	ADP
admet-1317	90	8	mn	mn	PROPN
admet-1317	90	9	arrays	array	VERB
admet-1317	90	10	prepared	prepare	VERB
admet-1317	90	11	with	with	ADP
admet-1317	90	12	different	different	ADJ
admet-1317	90	13	proportions	proportion	NOUN
admet-1317	90	14	of	of	ADP
admet-1317	90	15	ha	ha	INTJ
admet-1317	90	16	to	to	PART
admet-1317	90	17	penetrate	penetrate	VERB
admet-1317	90	18	the	the	DET
admet-1317	90	19	skin	skin	NOUN
admet-1317	90	20	and	and	CCONJ
admet-1317	90	21	form	form	NOUN
admet-1317	90	22	holes	hole	NOUN
admet-1317	90	23	,	,	PUNCT
admet-1317	90	24	an	an	DET
admet-1317	90	25	insertion	insertion	NOUN
admet-1317	90	26	and	and	CCONJ
admet-1317	90	27	staining	stain	VERB
admet-1317	90	28	test	test	NOUN
admet-1317	90	29	was	be	AUX
admet-1317	90	30	performed	perform	VERB
admet-1317	90	31	.	.	PUNCT
admet-1317	91	1	human	human	ADJ
admet-1317	91	2	skin	skin	NOUN
admet-1317	91	3	samples	sample	NOUN
admet-1317	91	4	were	be	AUX
admet-1317	91	5	obtained	obtain	VERB
admet-1317	91	6	from	from	ADP
admet-1317	91	7	32	32	NUM
admet-1317	91	8	years	year	NOUN
admet-1317	91	9	old	old	ADJ
admet-1317	91	10	female	female	NOUN
admet-1317	91	11	after	after	ADP
admet-1317	91	12	liposuction	liposuction	NOUN
admet-1317	91	13	surgery	surgery	NOUN
admet-1317	91	14	.	.	PUNCT
admet-1317	92	1	mn	mn	PROPN
admet-1317	92	2	arrays	array	VERB
admet-1317	92	3	were	be	AUX
admet-1317	92	4	inserted	insert	VERB
admet-1317	92	5	into	into	ADP
admet-1317	92	6	human	human	ADJ
admet-1317	92	7	skin	skin	NOUN
admet-1317	92	8	by	by	ADP
admet-1317	92	9	pressing	press	VERB
admet-1317	92	10	them	they	PRON
admet-1317	92	11	against	against	ADP
admet-1317	92	12	the	the	DET
admet-1317	92	13	skin	skin	NOUN
admet-1317	92	14	surface	surface	NOUN
admet-1317	92	15	for	for	ADP
admet-1317	92	16	1	1	NUM
admet-1317	92	17	minute	minute	NOUN
admet-1317	92	18	and	and	CCONJ
admet-1317	92	19	then	then	ADV
admet-1317	92	20	removed	remove	VERB
admet-1317	92	21	.	.	PUNCT
admet-1317	93	1	subsequently	subsequently	ADV
admet-1317	93	2	,	,	PUNCT
admet-1317	93	3	the	the	DET
admet-1317	93	4	skin	skin	NOUN
admet-1317	93	5	surface	surface	NOUN
admet-1317	93	6	was	be	AUX
admet-1317	93	7	subjected	subject	VERB
admet-1317	93	8	to	to	ADP
admet-1317	93	9	staining	stain	VERB
admet-1317	93	10	by	by	ADP
admet-1317	93	11	application	application	NOUN
admet-1317	93	12	of	of	ADP
admet-1317	93	13	methylene	methylene	ADJ
admet-1317	93	14	blue	blue	ADJ
admet-1317	93	15	dye	dye	NOUN
admet-1317	93	16	for	for	ADP
admet-1317	93	17	10	10	NUM
admet-1317	93	18	minutes	minute	NOUN
admet-1317	93	19	to	to	PART
admet-1317	93	20	identify	identify	VERB
admet-1317	93	21	the	the	DET
admet-1317	93	22	insertion	insertion	NOUN
admet-1317	93	23	sites	site	NOUN
admet-1317	93	24	.	.	PUNCT
admet-1317	94	1	after	after	ADP
admet-1317	94	2	that	that	PRON
admet-1317	94	3	,	,	PUNCT
admet-1317	94	4	the	the	DET
admet-1317	94	5	excess	excess	NOUN
admet-1317	94	6	of	of	ADP
admet-1317	94	7	the	the	DET
admet-1317	94	8	dye	dye	NOUN
admet-1317	94	9	was	be	AUX
admet-1317	94	10	removed	remove	VERB
admet-1317	94	11	by	by	ADP
admet-1317	94	12	tissue	tissue	NOUN
admet-1317	94	13	paper	paper	NOUN
admet-1317	94	14	and	and	CCONJ
admet-1317	94	15	the	the	DET
admet-1317	94	16	mn	mn	PROPN
admet-1317	94	17	treated	treat	VERB
admet-1317	94	18	skin	skin	NOUN
admet-1317	94	19	area	area	NOUN
admet-1317	94	20	was	be	AUX
admet-1317	94	21	observed	observe	VERB
admet-1317	94	22	using	use	VERB
admet-1317	94	23	a	a	DET
admet-1317	94	24	digital	digital	ADJ
admet-1317	94	25	microscope	microscope	NOUN
admet-1317	94	26	.	.	PUNCT
admet-1317	95	1	the	the	DET
admet-1317	95	2	insertion	insertion	NOUN
admet-1317	95	3	ratio	ratio	NOUN
admet-1317	95	4	for	for	ADP
admet-1317	95	5	each	each	DET
admet-1317	95	6	mn	mn	PROPN
admet-1317	95	7	array	array	NOUN
admet-1317	95	8	was	be	AUX
admet-1317	95	9	calculated	calculate	VERB
admet-1317	95	10	as	as	ADP
admet-1317	95	11	the	the	DET
admet-1317	95	12	number	number	NOUN
admet-1317	95	13	of	of	ADP
admet-1317	95	14	blue	blue	ADJ
admet-1317	95	15	spots	spot	NOUN
admet-1317	95	16	on	on	ADP
admet-1317	95	17	the	the	DET
admet-1317	95	18	skin	skin	NOUN
admet-1317	95	19	surface	surface	NOUN
admet-1317	95	20	divided	divide	VERB
admet-1317	95	21	by	by	ADP
admet-1317	95	22	the	the	DET
admet-1317	95	23	number	number	NOUN
admet-1317	95	24	of	of	ADP
admet-1317	95	25	needles	needle	NOUN
admet-1317	95	26	in	in	ADP
admet-1317	95	27	the	the	DET
admet-1317	95	28	array	array	NOUN
admet-1317	95	29	[	[	X
admet-1317	95	30	16	16	NUM
admet-1317	95	31	]	]	PUNCT
admet-1317	95	32	.	.	PUNCT
admet-1317	96	1	histological	histological	ADJ
admet-1317	96	2	examination	examination	NOUN
admet-1317	96	3	of	of	ADP
admet-1317	96	4	microneedles	microneedle	NOUN
admet-1317	96	5	treated	treat	VERB
admet-1317	96	6	skin	skin	NOUN
admet-1317	96	7	.	.	PUNCT
admet-1317	97	1	to	to	PART
admet-1317	97	2	demonstrate	demonstrate	VERB
admet-1317	97	3	the	the	DET
admet-1317	97	4	penetration	penetration	NOUN
admet-1317	97	5	depth	depth	NOUN
admet-1317	97	6	of	of	ADP
admet-1317	97	7	mns	mns	PROPN
admet-1317	97	8	,	,	PUNCT
admet-1317	97	9	a	a	DET
admet-1317	97	10	histological	histological	ADJ
admet-1317	97	11	examination	examination	NOUN
admet-1317	97	12	was	be	AUX
admet-1317	97	13	performed	perform	VERB
admet-1317	97	14	.	.	PUNCT
admet-1317	98	1	skin	skin	NOUN
admet-1317	98	2	cross	cross	ADJ
admet-1317	98	3	-	-	ADJ
admet-1317	98	4	sectioning	section	VERB
admet-1317	98	5	and	and	CCONJ
admet-1317	98	6	staining	stain	VERB
admet-1317	98	7	techniques	technique	NOUN
admet-1317	98	8	were	be	AUX
admet-1317	98	9	used	use	VERB
admet-1317	98	10	to	to	PART
admet-1317	98	11	assess	assess	VERB
admet-1317	98	12	the	the	DET
admet-1317	98	13	formation	formation	NOUN
admet-1317	98	14	of	of	ADP
admet-1317	98	15	microchannels	microchannel	NOUN
admet-1317	98	16	within	within	ADP
admet-1317	98	17	skin	skin	NOUN
admet-1317	98	18	layers	layer	NOUN
admet-1317	98	19	.	.	PUNCT
admet-1317	99	1	briefly	briefly	ADV
admet-1317	99	2	,	,	PUNCT
admet-1317	99	3	human	human	ADJ
admet-1317	99	4	skin	skin	NOUN
admet-1317	99	5	samples	sample	NOUN
admet-1317	99	6	treated	treat	VERB
admet-1317	99	7	with	with	ADP
admet-1317	99	8	mns	mns	PROPN
admet-1317	99	9	were	be	AUX
admet-1317	99	10	embedded	embed	VERB
admet-1317	99	11	in	in	ADP
admet-1317	99	12	paraffin	paraffin	NOUN
admet-1317	99	13	wax	wax	NOUN
admet-1317	99	14	blocks	block	NOUN
admet-1317	99	15	and	and	CCONJ
admet-1317	99	16	subjected	subject	VERB
admet-1317	99	17	to	to	ADP
admet-1317	99	18	cross	cross	VERB
admet-1317	99	19	-	-	ADJ
admet-1317	99	20	sectioning	section	VERB
admet-1317	99	21	into	into	ADP
admet-1317	99	22	5	5	NUM
admet-1317	99	23	μm	μm	NOUN
admet-1317	99	24	slices	slice	NOUN
admet-1317	99	25	using	use	VERB
admet-1317	99	26	an	an	DET
admet-1317	99	27	electrical	electrical	ADJ
admet-1317	99	28	admet	admet	NOUN
admet-1317	99	29	&	&	CCONJ
admet-1317	99	30	dmpk	dmpk	PROPN
admet-1317	99	31	10(3	10(3	NUM
admet-1317	99	32	)	)	PUNCT
admet-1317	99	33	(	(	PUNCT
admet-1317	99	34	2022	2022	NUM
admet-1317	99	35	)	)	PUNCT
admet-1317	99	36	213	213	NUM
admet-1317	99	37	-	-	SYM
admet-1317	99	38	230	230	NUM
admet-1317	99	39	transdermal	transdermal	ADJ
admet-1317	99	40	delivery	delivery	NOUN
admet-1317	99	41	of	of	ADP
admet-1317	99	42	levothyroxine	levothyroxine	NOUN
admet-1317	99	43	via	via	ADP
admet-1317	99	44	dissolving	dissolve	VERB
admet-1317	99	45	microneedles	microneedle	NOUN
admet-1317	99	46	doi	doi	PROPN
admet-1317	99	47	:	:	PUNCT
admet-1317	99	48	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	NUM
admet-1317	99	49	217	217	NUM
admet-1317	99	50	microtome	microtome	NOUN
admet-1317	99	51	.	.	PUNCT
admet-1317	100	1	these	these	DET
admet-1317	100	2	cross	cross	ADJ
admet-1317	100	3	-	-	ADJ
admet-1317	100	4	sectioned	sectioned	ADJ
admet-1317	100	5	skin	skin	NOUN
admet-1317	100	6	samples	sample	NOUN
admet-1317	100	7	were	be	AUX
admet-1317	100	8	then	then	ADV
admet-1317	100	9	stained	stain	VERB
admet-1317	100	10	with	with	ADP
admet-1317	100	11	hematoxylin	hematoxylin	NOUN
admet-1317	100	12	and	and	CCONJ
admet-1317	100	13	eosin	eosin	PROPN
admet-1317	100	14	(	(	PUNCT
admet-1317	100	15	h&e	h&e	PROPN
admet-1317	100	16	)	)	PUNCT
admet-1317	100	17	dyes	dye	NOUN
admet-1317	100	18	to	to	PART
admet-1317	100	19	be	be	AUX
admet-1317	100	20	examined	examine	VERB
admet-1317	100	21	under	under	ADP
admet-1317	100	22	a	a	DET
admet-1317	100	23	light	light	ADJ
admet-1317	100	24	microscope	microscope	NOUN
admet-1317	100	25	[	[	X
admet-1317	100	26	24	24	NUM
admet-1317	100	27	]	]	PUNCT
admet-1317	100	28	.	.	PUNCT
admet-1317	101	1	in	in	ADP
admet-1317	101	2	vivo	vivo	ADJ
admet-1317	101	3	dissolution	dissolution	NOUN
admet-1317	101	4	study	study	NOUN
admet-1317	101	5	.	.	PUNCT
admet-1317	102	1	in	in	ADP
admet-1317	102	2	vivo	vivo	ADJ
admet-1317	102	3	dissolution	dissolution	NOUN
admet-1317	102	4	study	study	NOUN
admet-1317	102	5	of	of	ADP
admet-1317	102	6	the	the	DET
admet-1317	102	7	f11	f11	PROPN
admet-1317	102	8	mn	mn	PROPN
admet-1317	102	9	array	array	NOUN
admet-1317	102	10	was	be	AUX
admet-1317	102	11	performed	perform	VERB
admet-1317	102	12	using	use	VERB
admet-1317	102	13	2	2	NUM
admet-1317	102	14	month	month	NOUN
admet-1317	102	15	old	old	ADJ
admet-1317	102	16	rats	rat	NOUN
admet-1317	102	17	weighing	weigh	VERB
admet-1317	102	18	approximately	approximately	ADV
admet-1317	102	19	147	147	NUM
admet-1317	102	20	-	-	SYM
admet-1317	102	21	150	150	NUM
admet-1317	102	22	g	g	NOUN
admet-1317	102	23	(	(	PUNCT
admet-1317	102	24	n	n	NOUN
admet-1317	102	25	=	=	SYM
admet-1317	102	26	3	3	NUM
admet-1317	102	27	)	)	PUNCT
admet-1317	102	28	.	.	PUNCT
admet-1317	103	1	the	the	DET
admet-1317	103	2	mns	mns	PROPN
admet-1317	103	3	arrays	array	NOUN
admet-1317	103	4	were	be	AUX
admet-1317	103	5	inserted	insert	VERB
admet-1317	103	6	in	in	ADP
admet-1317	103	7	the	the	DET
admet-1317	103	8	rat	rat	NOUN
admet-1317	103	9	skin	skin	NOUN
admet-1317	103	10	for	for	ADP
admet-1317	103	11	different	different	ADJ
admet-1317	103	12	time	time	NOUN
admet-1317	103	13	intervals	interval	NOUN
admet-1317	103	14	of	of	ADP
admet-1317	103	15	0	0	NUM
admet-1317	103	16	,	,	PUNCT
admet-1317	103	17	5	5	NUM
admet-1317	103	18	,	,	PUNCT
admet-1317	103	19	10	10	NUM
admet-1317	103	20	,	,	PUNCT
admet-1317	103	21	20	20	NUM
admet-1317	103	22	,	,	PUNCT
admet-1317	103	23	30	30	NUM
admet-1317	103	24	and	and	CCONJ
admet-1317	103	25	60	60	NUM
admet-1317	103	26	minutes	minute	NOUN
admet-1317	103	27	.	.	PUNCT
admet-1317	104	1	after	after	ADP
admet-1317	104	2	that	that	PRON
admet-1317	104	3	,	,	PUNCT
admet-1317	104	4	the	the	DET
admet-1317	104	5	mn	mn	PROPN
admet-1317	104	6	arrays	array	VERB
admet-1317	104	7	were	be	AUX
admet-1317	104	8	removed	remove	VERB
admet-1317	104	9	at	at	ADP
admet-1317	104	10	each	each	DET
admet-1317	104	11	specific	specific	ADJ
admet-1317	104	12	time	time	NOUN
admet-1317	104	13	point	point	NOUN
admet-1317	104	14	to	to	PART
admet-1317	104	15	be	be	AUX
admet-1317	104	16	examined	examine	VERB
admet-1317	104	17	under	under	ADP
admet-1317	104	18	a	a	DET
admet-1317	104	19	light	light	ADJ
admet-1317	104	20	microscope	microscope	NOUN
admet-1317	104	21	[	[	X
admet-1317	104	22	25	25	NUM
admet-1317	104	23	]	]	PUNCT
admet-1317	104	24	.	.	PUNCT
admet-1317	105	1	ethical	ethical	ADJ
admet-1317	105	2	approval	approval	NOUN
admet-1317	105	3	for	for	ADP
admet-1317	105	4	all	all	DET
admet-1317	105	5	animal	animal	NOUN
admet-1317	105	6	studies	study	NOUN
admet-1317	105	7	in	in	ADP
admet-1317	105	8	this	this	DET
admet-1317	105	9	research	research	NOUN
admet-1317	105	10	was	be	AUX
admet-1317	105	11	obtained	obtain	VERB
admet-1317	105	12	from	from	ADP
admet-1317	105	13	the	the	DET
admet-1317	105	14	animal	animal	NOUN
admet-1317	105	15	ethics	ethic	NOUN
admet-1317	105	16	committee	committee	PROPN
admet-1317	105	17	(	(	PUNCT
admet-1317	105	18	aec	aec	PROPN
admet-1317	105	19	)	)	PUNCT
admet-1317	105	20	of	of	ADP
admet-1317	105	21	the	the	DET
admet-1317	105	22	college	college	NOUN
admet-1317	105	23	of	of	ADP
admet-1317	105	24	pharmacy/	pharmacy/	NUM
admet-1317	105	25	mustansiriyah	mustansiriyah	NOUN
admet-1317	105	26	university/	university/	NUM
admet-1317	105	27	iraq	iraq	PROPN
admet-1317	105	28	-	-	PUNCT
admet-1317	105	29	baghdad	baghdad	PROPN
admet-1317	105	30	under	under	ADP
admet-1317	105	31	license	license	NOUN
admet-1317	105	32	no	no	NOUN
admet-1317	105	33	.	.	NOUN
admet-1317	105	34	9	9	NUM
admet-1317	105	35	.	.	X
admet-1317	106	1	visualization	visualization	NOUN
admet-1317	106	2	of	of	ADP
admet-1317	106	3	microneedles	microneedle	NOUN
admet-1317	106	4	by	by	ADP
admet-1317	106	5	scanning	scan	VERB
admet-1317	106	6	electron	electron	NOUN
admet-1317	106	7	microscopy	microscopy	NOUN
admet-1317	106	8	(	(	PUNCT
admet-1317	106	9	sem	sem	NOUN
admet-1317	106	10	)	)	PUNCT
admet-1317	106	11	.	.	PUNCT
admet-1317	107	1	the	the	DET
admet-1317	107	2	morphological	morphological	ADJ
admet-1317	107	3	characteristics	characteristic	NOUN
admet-1317	107	4	and	and	CCONJ
admet-1317	107	5	dimensions	dimension	NOUN
admet-1317	107	6	of	of	ADP
admet-1317	107	7	the	the	DET
admet-1317	107	8	mns	mns	PROPN
admet-1317	107	9	were	be	AUX
admet-1317	107	10	determined	determine	VERB
admet-1317	107	11	using	use	VERB
admet-1317	107	12	a	a	DET
admet-1317	107	13	tescan	tescan	ADJ
admet-1317	107	14	mira	mira	NOUN
admet-1317	107	15	3	3	NUM
admet-1317	107	16	sem	sem	NOUN
admet-1317	107	17	instrument	instrument	NOUN
admet-1317	107	18	.	.	PUNCT
admet-1317	108	1	in	in	ADP
admet-1317	108	2	this	this	DET
admet-1317	108	3	test	test	NOUN
admet-1317	108	4	,	,	PUNCT
admet-1317	108	5	a	a	DET
admet-1317	108	6	mn	mn	PROPN
admet-1317	108	7	array	array	NOUN
admet-1317	108	8	was	be	AUX
admet-1317	108	9	fixed	fix	VERB
admet-1317	108	10	on	on	ADP
admet-1317	108	11	an	an	DET
admet-1317	108	12	aluminum	aluminum	NOUN
admet-1317	108	13	plate	plate	NOUN
admet-1317	108	14	with	with	ADP
admet-1317	108	15	adhesive	adhesive	ADJ
admet-1317	108	16	tape	tape	NOUN
admet-1317	108	17	and	and	CCONJ
admet-1317	108	18	covered	cover	VERB
admet-1317	108	19	with	with	ADP
admet-1317	108	20	gold	gold	NOUN
admet-1317	108	21	/	/	SYM
admet-1317	108	22	palladium	palladium	NOUN
admet-1317	108	23	of	of	ADP
admet-1317	108	24	20	20	NUM
admet-1317	108	25	μm	μm	NUM
admet-1317	108	26	thickness	thickness	NOUN
admet-1317	108	27	.	.	PUNCT
admet-1317	109	1	the	the	DET
admet-1317	109	2	accelerating	accelerate	VERB
admet-1317	109	3	voltage	voltage	NOUN
admet-1317	109	4	was	be	AUX
admet-1317	109	5	15	15	NUM
admet-1317	109	6	kv	kv	NOUN
admet-1317	109	7	and	and	CCONJ
admet-1317	109	8	the	the	DET
admet-1317	109	9	time	time	NOUN
admet-1317	109	10	of	of	ADP
admet-1317	109	11	the	the	DET
admet-1317	109	12	test	test	NOUN
admet-1317	109	13	was	be	AUX
admet-1317	109	14	2	2	NUM
admet-1317	109	15	minutes	minute	NOUN
admet-1317	109	16	.	.	PUNCT
admet-1317	110	1	a	a	DET
admet-1317	110	2	mn	mn	PROPN
admet-1317	110	3	array	array	NOUN
admet-1317	110	4	was	be	AUX
admet-1317	110	5	tested	test	VERB
admet-1317	110	6	by	by	ADP
admet-1317	110	7	sem	sem	PROPN
admet-1317	110	8	at	at	ADP
admet-1317	110	9	different	different	ADJ
admet-1317	110	10	magnifications	magnification	NOUN
admet-1317	110	11	;	;	PUNCT
admet-1317	110	12	50	50	NUM
admet-1317	110	13	,	,	PUNCT
admet-1317	110	14	100	100	NUM
admet-1317	110	15	and	and	CCONJ
admet-1317	110	16	500	500	NUM
admet-1317	110	17	x	x	NOUN
admet-1317	110	18	,	,	PUNCT
admet-1317	110	19	to	to	PART
admet-1317	110	20	show	show	VERB
admet-1317	110	21	the	the	DET
admet-1317	110	22	needles	needle	NOUN
admet-1317	110	23	’	'	PUNCT
admet-1317	110	24	length	length	NOUN
admet-1317	110	25	,	,	PUNCT
admet-1317	110	26	width	width	NOUN
admet-1317	110	27	,	,	PUNCT
admet-1317	110	28	needle	needle	NOUN
admet-1317	110	29	tip	tip	NOUN
admet-1317	110	30	diameter	diameter	NOUN
admet-1317	110	31	and	and	CCONJ
admet-1317	110	32	distance	distance	NOUN
admet-1317	110	33	between	between	ADP
admet-1317	110	34	needles	needle	NOUN
admet-1317	110	35	[	[	X
admet-1317	110	36	17	17	NUM
admet-1317	110	37	]	]	PUNCT
admet-1317	110	38	.	.	PUNCT
admet-1317	111	1	the	the	DET
admet-1317	111	2	sem	sem	NOUN
admet-1317	111	3	images	image	NOUN
admet-1317	111	4	were	be	AUX
admet-1317	111	5	captured	capture	VERB
admet-1317	111	6	using	use	VERB
admet-1317	111	7	tescan	tescan	PROPN
admet-1317	111	8	’s	’s	PART
admet-1317	111	9	essence	essence	NOUN
admet-1317	111	10	software	software	NOUN
admet-1317	111	11	.	.	PUNCT
admet-1317	112	1	ex	ex	PRON
admet-1317	112	2	vivo	vivo	ADJ
admet-1317	112	3	permeation	permeation	NOUN
admet-1317	112	4	study	study	NOUN
admet-1317	112	5	.	.	PUNCT
admet-1317	113	1	franz	franz	PROPN
admet-1317	113	2	diffusion	diffusion	NOUN
admet-1317	113	3	cells	cell	NOUN
admet-1317	113	4	with	with	ADP
admet-1317	113	5	an	an	DET
admet-1317	113	6	exposed	expose	VERB
admet-1317	113	7	surface	surface	NOUN
admet-1317	113	8	area	area	NOUN
admet-1317	113	9	of	of	ADP
admet-1317	113	10	0.785	0.785	NUM
admet-1317	113	11	cm²	cm²	NOUN
admet-1317	113	12	were	be	AUX
admet-1317	113	13	used	use	VERB
admet-1317	113	14	to	to	PART
admet-1317	113	15	investigate	investigate	VERB
admet-1317	113	16	the	the	DET
admet-1317	113	17	permeation	permeation	NOUN
admet-1317	113	18	of	of	ADP
admet-1317	113	19	lt-4	lt-4	NOUN
admet-1317	113	20	sodium	sodium	NOUN
admet-1317	113	21	from	from	ADP
admet-1317	113	22	the	the	DET
admet-1317	113	23	optimum	optimum	ADJ
admet-1317	113	24	mn	mn	PROPN
admet-1317	113	25	array	array	NOUN
admet-1317	113	26	formula	formula	NOUN
admet-1317	113	27	f11	f11	NOUN
admet-1317	113	28	across	across	ADP
admet-1317	113	29	human	human	ADJ
admet-1317	113	30	skin	skin	NOUN
admet-1317	113	31	.	.	PUNCT
admet-1317	114	1	skin	skin	NOUN
admet-1317	114	2	samples	sample	NOUN
admet-1317	114	3	were	be	AUX
admet-1317	114	4	obtained	obtain	VERB
admet-1317	114	5	from	from	ADP
admet-1317	114	6	the	the	DET
admet-1317	114	7	abdomen	abdomen	NOUN
admet-1317	114	8	of	of	ADP
admet-1317	114	9	32	32	NUM
admet-1317	114	10	years	year	NOUN
admet-1317	114	11	old	old	ADJ
admet-1317	114	12	woman	woman	NOUN
admet-1317	114	13	who	who	PRON
admet-1317	114	14	had	have	AUX
admet-1317	114	15	undergone	undergo	VERB
admet-1317	114	16	a	a	DET
admet-1317	114	17	plastic	plastic	ADJ
admet-1317	114	18	surgery	surgery	NOUN
admet-1317	114	19	operation	operation	NOUN
admet-1317	114	20	[	[	X
admet-1317	114	21	19	19	NUM
admet-1317	114	22	]	]	PUNCT
admet-1317	114	23	.	.	PUNCT
admet-1317	115	1	a	a	DET
admet-1317	115	2	consent	consent	NOUN
admet-1317	115	3	form	form	NOUN
admet-1317	115	4	was	be	AUX
admet-1317	115	5	obtained	obtain	VERB
admet-1317	115	6	from	from	ADP
admet-1317	115	7	the	the	DET
admet-1317	115	8	patient	patient	NOUN
admet-1317	115	9	to	to	PART
admet-1317	115	10	collect	collect	VERB
admet-1317	115	11	and	and	CCONJ
admet-1317	115	12	use	use	VERB
admet-1317	115	13	her	her	PRON
admet-1317	115	14	excised	excised	ADJ
admet-1317	115	15	skin	skin	NOUN
admet-1317	115	16	in	in	ADP
admet-1317	115	17	ex	ex	PRON
admet-1317	115	18	vivo	vivo	ADJ
admet-1317	115	19	experiments	experiment	NOUN
admet-1317	115	20	.	.	PUNCT
admet-1317	116	1	the	the	DET
admet-1317	116	2	skin	skin	NOUN
admet-1317	116	3	was	be	AUX
admet-1317	116	4	washed	wash	VERB
admet-1317	116	5	with	with	ADP
admet-1317	116	6	normal	normal	ADJ
admet-1317	116	7	saline	saline	NOUN
admet-1317	116	8	and	and	CCONJ
admet-1317	116	9	dried	dry	VERB
admet-1317	116	10	using	use	VERB
admet-1317	116	11	tissue	tissue	NOUN
admet-1317	116	12	paper	paper	NOUN
admet-1317	116	13	.	.	PUNCT
admet-1317	117	1	after	after	ADP
admet-1317	117	2	that	that	PRON
admet-1317	117	3	,	,	PUNCT
admet-1317	117	4	skin	skin	NOUN
admet-1317	117	5	samples	sample	NOUN
admet-1317	117	6	were	be	AUX
admet-1317	117	7	wrapped	wrap	VERB
admet-1317	117	8	in	in	ADP
admet-1317	117	9	an	an	DET
admet-1317	117	10	aluminum	aluminum	NOUN
admet-1317	117	11	foil	foil	NOUN
admet-1317	117	12	and	and	CCONJ
admet-1317	117	13	stored	store	VERB
admet-1317	117	14	at	at	ADP
admet-1317	117	15	-20	-20	NUM
admet-1317	117	16	°	°	ADP
admet-1317	117	17	c	c	NOUN
admet-1317	117	18	until	until	SCONJ
admet-1317	117	19	required	require	VERB
admet-1317	117	20	.	.	PUNCT
admet-1317	118	1	skin	skin	NOUN
admet-1317	118	2	samples	sample	NOUN
admet-1317	118	3	were	be	AUX
admet-1317	118	4	used	use	VERB
admet-1317	118	5	within	within	ADP
admet-1317	118	6	a	a	DET
admet-1317	118	7	month	month	NOUN
admet-1317	118	8	of	of	ADP
admet-1317	118	9	storage	storage	NOUN
admet-1317	118	10	.	.	PUNCT
admet-1317	119	1	prior	prior	ADV
admet-1317	119	2	to	to	ADP
admet-1317	119	3	starting	start	VERB
admet-1317	119	4	the	the	DET
admet-1317	119	5	experiment	experiment	NOUN
admet-1317	119	6	,	,	PUNCT
admet-1317	119	7	skin	skin	NOUN
admet-1317	119	8	samples	sample	NOUN
admet-1317	119	9	were	be	AUX
admet-1317	119	10	soaked	soak	VERB
admet-1317	119	11	for	for	ADP
admet-1317	119	12	1	1	NUM
admet-1317	119	13	hour	hour	NOUN
admet-1317	119	14	in	in	ADP
admet-1317	119	15	normal	normal	ADJ
admet-1317	119	16	saline	saline	NOUN
admet-1317	119	17	to	to	PART
admet-1317	119	18	hydrate	hydrate	VERB
admet-1317	119	19	them	they	PRON
admet-1317	119	20	and	and	CCONJ
admet-1317	119	21	then	then	ADV
admet-1317	119	22	they	they	PRON
admet-1317	119	23	were	be	AUX
admet-1317	119	24	placed	place	VERB
admet-1317	119	25	on	on	ADP
admet-1317	119	26	a	a	DET
admet-1317	119	27	flat	flat	ADJ
admet-1317	119	28	desk	desk	NOUN
admet-1317	119	29	with	with	ADP
admet-1317	119	30	the	the	DET
admet-1317	119	31	stratum	stratum	NOUN
admet-1317	119	32	corneum	corneum	NOUN
admet-1317	119	33	facing	face	VERB
admet-1317	119	34	upwards	upwards	ADV
admet-1317	119	35	.	.	PUNCT
admet-1317	120	1	subsequently	subsequently	ADV
admet-1317	120	2	,	,	PUNCT
admet-1317	120	3	ha	ha	INTJ
admet-1317	120	4	mn	mn	PROPN
admet-1317	120	5	arrays	array	NOUN
admet-1317	120	6	were	be	AUX
admet-1317	120	7	physically	physically	ADV
admet-1317	120	8	pressed	press	VERB
admet-1317	120	9	onto	onto	ADP
admet-1317	120	10	the	the	DET
admet-1317	120	11	skin	skin	NOUN
admet-1317	120	12	for	for	ADP
admet-1317	120	13	30	30	NUM
admet-1317	120	14	seconds	second	NOUN
admet-1317	120	15	and	and	CCONJ
admet-1317	120	16	secured	secure	VERB
admet-1317	120	17	using	use	VERB
admet-1317	120	18	adhesive	adhesive	ADJ
admet-1317	120	19	tape	tape	NOUN
admet-1317	120	20	clamped	clamp	VERB
admet-1317	120	21	between	between	ADP
admet-1317	120	22	the	the	DET
admet-1317	120	23	donor	donor	NOUN
admet-1317	120	24	and	and	CCONJ
admet-1317	120	25	receptor	receptor	NOUN
admet-1317	120	26	chambers	chamber	NOUN
admet-1317	120	27	.	.	PUNCT
admet-1317	121	1	the	the	DET
admet-1317	121	2	receptor	receptor	NOUN
admet-1317	121	3	chamber	chamber	NOUN
admet-1317	121	4	was	be	AUX
admet-1317	121	5	filled	fill	VERB
admet-1317	121	6	with	with	ADP
admet-1317	121	7	10	10	NUM
admet-1317	121	8	ml	ml	NOUN
admet-1317	121	9	of	of	ADP
admet-1317	121	10	solvent	solvent	NOUN
admet-1317	121	11	mixture	mixture	NOUN
admet-1317	121	12	(	(	PUNCT
admet-1317	121	13	ethanol	ethanol	NOUN
admet-1317	121	14	25	25	NUM
admet-1317	121	15	%	%	NOUN
admet-1317	121	16	v	v	ADP
admet-1317	121	17	/	/	SYM
admet-1317	121	18	v	v	NOUN
admet-1317	122	1	and	and	CCONJ
admet-1317	122	2	dw	dw	NOUN
admet-1317	122	3	75	75	NUM
admet-1317	122	4	%	%	NOUN
admet-1317	122	5	v	v	ADP
admet-1317	122	6	/	/	SYM
admet-1317	122	7	v	v	NOUN
admet-1317	122	8	)	)	PUNCT
admet-1317	122	9	as	as	ADP
admet-1317	122	10	a	a	DET
admet-1317	122	11	receptor	receptor	NOUN
admet-1317	122	12	fluid	fluid	NOUN
admet-1317	122	13	.	.	PUNCT
admet-1317	123	1	franz	franz	PROPN
admet-1317	123	2	cells	cell	NOUN
admet-1317	123	3	(	(	PUNCT
admet-1317	123	4	n	n	NOUN
admet-1317	123	5	=	=	SYM
admet-1317	123	6	6	6	NUM
admet-1317	123	7	)	)	PUNCT
admet-1317	123	8	were	be	AUX
admet-1317	123	9	then	then	ADV
admet-1317	123	10	placed	place	VERB
admet-1317	123	11	in	in	ADP
admet-1317	123	12	diffusion	diffusion	NOUN
admet-1317	123	13	cells	cell	NOUN
admet-1317	123	14	apparatus	apparatus	NOUN
admet-1317	123	15	at	at	ADP
admet-1317	123	16	37	37	NUM
admet-1317	123	17	°	°	NOUN
admet-1317	123	18	c	c	NOUN
admet-1317	123	19	.	.	PUNCT
admet-1317	124	1	the	the	DET
admet-1317	124	2	receptor	receptor	NOUN
admet-1317	124	3	fluid	fluid	NOUN
admet-1317	124	4	was	be	AUX
admet-1317	124	5	stirred	stir	VERB
admet-1317	124	6	continuously	continuously	ADV
admet-1317	124	7	by	by	ADP
admet-1317	124	8	a	a	DET
admet-1317	124	9	small	small	ADJ
admet-1317	124	10	teflon	teflon	NOUN
admet-1317	124	11	-	-	PUNCT
admet-1317	124	12	coated	coat	VERB
admet-1317	124	13	magnetic	magnetic	ADJ
admet-1317	124	14	bar	bar	NOUN
admet-1317	124	15	at	at	ADP
admet-1317	124	16	400	400	NUM
admet-1317	124	17	rpm	rpm	NOUN
admet-1317	124	18	.	.	PUNCT
admet-1317	125	1	samples	sample	NOUN
admet-1317	125	2	of	of	ADP
admet-1317	125	3	1	1	NUM
admet-1317	125	4	ml	ml	NOUN
admet-1317	125	5	were	be	AUX
admet-1317	125	6	withdrawn	withdraw	VERB
admet-1317	125	7	from	from	ADP
admet-1317	125	8	the	the	DET
admet-1317	125	9	receptor	receptor	NOUN
admet-1317	125	10	fluid	fluid	NOUN
admet-1317	125	11	and	and	CCONJ
admet-1317	125	12	replaced	replace	VERB
admet-1317	125	13	with	with	ADP
admet-1317	125	14	a	a	DET
admet-1317	125	15	pre	pre	ADJ
admet-1317	125	16	-	-	ADJ
admet-1317	125	17	heated	heated	ADJ
admet-1317	125	18	fresh	fresh	ADJ
admet-1317	125	19	medium	medium	NOUN
admet-1317	125	20	following	follow	VERB
admet-1317	125	21	each	each	DET
admet-1317	125	22	sampling	sample	VERB
admet-1317	125	23	time	time	NOUN
admet-1317	125	24	(	(	PUNCT
admet-1317	125	25	10	10	NUM
admet-1317	125	26	,	,	PUNCT
admet-1317	125	27	30	30	NUM
admet-1317	125	28	,	,	PUNCT
admet-1317	125	29	60	60	NUM
admet-1317	125	30	,	,	PUNCT
admet-1317	125	31	90	90	NUM
admet-1317	125	32	,	,	PUNCT
admet-1317	125	33	180	180	NUM
admet-1317	125	34	,	,	PUNCT
admet-1317	125	35	300	300	NUM
admet-1317	125	36	and	and	CCONJ
admet-1317	125	37	420	420	NUM
admet-1317	125	38	minutes	minute	NOUN
admet-1317	125	39	)	)	PUNCT
admet-1317	125	40	to	to	PART
admet-1317	125	41	maintain	maintain	VERB
admet-1317	125	42	the	the	DET
admet-1317	125	43	sink	sink	NOUN
admet-1317	125	44	condition	condition	NOUN
admet-1317	125	45	.	.	PUNCT
admet-1317	126	1	the	the	DET
admet-1317	126	2	withdrawn	withdraw	VERB
admet-1317	126	3	samples	sample	NOUN
admet-1317	126	4	were	be	AUX
admet-1317	126	5	then	then	ADV
admet-1317	126	6	assayed	assay	VERB
admet-1317	126	7	by	by	ADP
admet-1317	126	8	a	a	DET
admet-1317	126	9	uv	uv	NOUN
admet-1317	126	10	spectrophotometer	spectrophotometer	NOUN
admet-1317	126	11	to	to	PART
admet-1317	126	12	determine	determine	VERB
admet-1317	126	13	the	the	DET
admet-1317	126	14	concentration	concentration	NOUN
admet-1317	126	15	of	of	ADP
admet-1317	126	16	lt-4	lt-4	NOUN
admet-1317	126	17	sodium	sodium	NOUN
admet-1317	126	18	.	.	PUNCT
admet-1317	127	1	for	for	ADP
admet-1317	127	2	comparison	comparison	NOUN
admet-1317	127	3	,	,	PUNCT
admet-1317	127	4	control	control	NOUN
admet-1317	127	5	formulas	formula	NOUN
admet-1317	127	6	containing	contain	VERB
admet-1317	127	7	the	the	DET
admet-1317	127	8	same	same	ADJ
admet-1317	127	9	ingredients	ingredient	NOUN
admet-1317	127	10	of	of	ADP
admet-1317	127	11	the	the	DET
admet-1317	127	12	optimum	optimum	ADJ
admet-1317	127	13	formula	formula	NOUN
admet-1317	127	14	,	,	PUNCT
admet-1317	127	15	one	one	NUM
admet-1317	127	16	in	in	ADP
admet-1317	127	17	a	a	DET
admet-1317	127	18	liquid	liquid	ADJ
admet-1317	127	19	form	form	NOUN
admet-1317	127	20	and	and	CCONJ
admet-1317	127	21	another	another	DET
admet-1317	127	22	one	one	NOUN
admet-1317	127	23	as	as	ADP
admet-1317	127	24	a	a	DET
admet-1317	127	25	film	film	NOUN
admet-1317	127	26	without	without	ADP
admet-1317	127	27	needles	needle	NOUN
admet-1317	127	28	(	(	PUNCT
admet-1317	127	29	needle	needle	NOUN
admet-1317	127	30	-	-	PUNCT
admet-1317	127	31	free	free	ADJ
admet-1317	127	32	)	)	PUNCT
admet-1317	127	33	,	,	PUNCT
admet-1317	127	34	were	be	AUX
admet-1317	127	35	prepared	prepared	ADJ
admet-1317	127	36	to	to	PART
admet-1317	127	37	highlight	highlight	VERB
admet-1317	127	38	the	the	DET
admet-1317	127	39	influence	influence	NOUN
admet-1317	127	40	of	of	ADP
admet-1317	127	41	needles	needle	NOUN
admet-1317	127	42	on	on	ADP
admet-1317	127	43	lt-4	lt-4	ADJ
admet-1317	127	44	sodium	sodium	NOUN
admet-1317	127	45	permeation	permeation	NOUN
admet-1317	127	46	.	.	PUNCT
admet-1317	128	1	the	the	DET
admet-1317	128	2	control	control	NOUN
admet-1317	128	3	formulas	formula	NOUN
admet-1317	128	4	were	be	AUX
admet-1317	128	5	tested	test	VERB
admet-1317	128	6	for	for	ADP
admet-1317	128	7	skin	skin	NOUN
admet-1317	128	8	permeation	permeation	NOUN
admet-1317	128	9	under	under	ADP
admet-1317	128	10	the	the	DET
admet-1317	128	11	same	same	ADJ
admet-1317	128	12	experimental	experimental	ADJ
admet-1317	128	13	conditions	condition	NOUN
admet-1317	128	14	as	as	SCONJ
admet-1317	128	15	the	the	DET
admet-1317	128	16	ha	ha	INTJ
admet-1317	128	17	mn	mn	PROPN
admet-1317	128	18	arrays	array	VERB
admet-1317	128	19	.	.	PUNCT
admet-1317	129	1	the	the	DET
admet-1317	129	2	cumulative	cumulative	ADJ
admet-1317	129	3	amount	amount	NOUN
admet-1317	129	4	of	of	ADP
admet-1317	129	5	lt-4	lt-4	NOUN
admet-1317	129	6	sodium	sodium	NOUN
admet-1317	129	7	was	be	AUX
admet-1317	129	8	plotted	plot	VERB
admet-1317	129	9	against	against	ADP
admet-1317	129	10	time	time	NOUN
admet-1317	129	11	to	to	PART
admet-1317	129	12	calculate	calculate	VERB
admet-1317	129	13	the	the	DET
admet-1317	129	14	flux	flux	NOUN
admet-1317	129	15	and	and	CCONJ
admet-1317	129	16	percentage	percentage	NOUN
admet-1317	129	17	of	of	ADP
admet-1317	129	18	the	the	DET
admet-1317	129	19	dose	dose	NOUN
admet-1317	129	20	delivered	deliver	VERB
admet-1317	129	21	across	across	ADP
admet-1317	129	22	the	the	DET
admet-1317	129	23	skin	skin	NOUN
admet-1317	129	24	[	[	X
admet-1317	129	25	26	26	NUM
admet-1317	129	26	]	]	PUNCT
admet-1317	129	27	.	.	PUNCT
admet-1317	130	1	skin	skin	NOUN
admet-1317	130	2	irritation	irritation	NOUN
admet-1317	130	3	test	test	NOUN
admet-1317	130	4	.	.	PUNCT
admet-1317	131	1	draize	draize	PROPN
admet-1317	131	2	test	test	NOUN
admet-1317	131	3	was	be	AUX
admet-1317	131	4	chosen	choose	VERB
admet-1317	131	5	to	to	PART
admet-1317	131	6	notice	notice	VERB
admet-1317	131	7	erythema	erythema	ADJ
admet-1317	131	8	and	and	CCONJ
admet-1317	131	9	edema	edema	VERB
admet-1317	131	10	on	on	ADP
admet-1317	131	11	the	the	DET
admet-1317	131	12	rat	rat	NOUN
admet-1317	131	13	skin	skin	NOUN
admet-1317	131	14	following	follow	VERB
admet-1317	131	15	the	the	DET
admet-1317	131	16	application	application	NOUN
admet-1317	131	17	of	of	ADP
admet-1317	131	18	mn	mn	PROPN
admet-1317	131	19	arrays	array	VERB
admet-1317	132	1	[	[	X
admet-1317	132	2	27	27	NUM
admet-1317	132	3	]	]	PUNCT
admet-1317	132	4	.	.	PUNCT
admet-1317	133	1	three	three	NUM
admet-1317	133	2	healthy	healthy	ADJ
admet-1317	133	3	rats	rat	NOUN
admet-1317	133	4	were	be	AUX
admet-1317	133	5	selected	select	VERB
admet-1317	133	6	and	and	CCONJ
admet-1317	133	7	their	their	PRON
admet-1317	133	8	skin	skin	NOUN
admet-1317	133	9	was	be	AUX
admet-1317	133	10	determined	determine	VERB
admet-1317	133	11	to	to	PART
admet-1317	133	12	be	be	AUX
admet-1317	133	13	normal	normal	ADJ
admet-1317	133	14	in	in	ADP
admet-1317	133	15	the	the	DET
admet-1317	133	16	absence	absence	NOUN
admet-1317	133	17	of	of	ADP
admet-1317	133	18	a	a	DET
admet-1317	133	19	scratch	scratch	NOUN
admet-1317	133	20	or	or	CCONJ
admet-1317	133	21	wound	wound	NOUN
admet-1317	133	22	.	.	PUNCT
admet-1317	134	1	twenty	twenty	NUM
admet-1317	134	2	-	-	PUNCT
admet-1317	134	3	four	four	NUM
admet-1317	134	4	hours	hour	NOUN
admet-1317	134	5	before	before	ADP
admet-1317	134	6	the	the	DET
admet-1317	134	7	test	test	NOUN
admet-1317	134	8	,	,	PUNCT
admet-1317	134	9	the	the	DET
admet-1317	134	10	rats	rat	NOUN
admet-1317	134	11	’	'	PUNCT
admet-1317	134	12	back	back	ADJ
admet-1317	134	13	skin	skin	NOUN
admet-1317	134	14	was	be	AUX
admet-1317	134	15	shaved	shave	VERB
admet-1317	134	16	.	.	PUNCT
admet-1317	135	1	after	after	ADP
admet-1317	135	2	that	that	PRON
admet-1317	135	3	,	,	PUNCT
admet-1317	135	4	the	the	DET
admet-1317	135	5	mn	mn	PROPN
admet-1317	135	6	arrays	array	VERB
admet-1317	135	7	were	be	AUX
admet-1317	135	8	fixed	fix	VERB
admet-1317	135	9	to	to	ADP
admet-1317	135	10	the	the	DET
admet-1317	135	11	skin	skin	NOUN
admet-1317	135	12	for	for	ADP
admet-1317	135	13	two	two	NUM
admet-1317	135	14	hours	hour	NOUN
admet-1317	135	15	.	.	PUNCT
admet-1317	136	1	following	follow	VERB
admet-1317	136	2	the	the	DET
admet-1317	136	3	removal	removal	NOUN
admet-1317	136	4	of	of	ADP
admet-1317	136	5	the	the	DET
admet-1317	136	6	mn	mn	PROPN
admet-1317	136	7	arrays	arrays	AUX
admet-1317	136	8	,	,	PUNCT
admet-1317	136	9	draize	draize	VERB
admet-1317	136	10	dermal	dermal	ADJ
admet-1317	136	11	scoring	scoring	NOUN
admet-1317	136	12	criteria	criterion	NOUN
admet-1317	136	13	were	be	AUX
admet-1317	136	14	used	use	VERB
admet-1317	136	15	to	to	PART
admet-1317	136	16	evaluate	evaluate	VERB
admet-1317	136	17	the	the	DET
admet-1317	136	18	erythema	erythema	NOUN
admet-1317	136	19	and	and	CCONJ
admet-1317	136	20	edema	edema	NOUN
admet-1317	136	21	at	at	ADP
admet-1317	136	22	1	1	NUM
admet-1317	136	23	,	,	PUNCT
admet-1317	136	24	24	24	NUM
admet-1317	136	25	and	and	CCONJ
admet-1317	136	26	72	72	NUM
admet-1317	136	27	hours	hour	NOUN
admet-1317	137	1	[	[	X
admet-1317	137	2	27	27	NUM
admet-1317	137	3	]	]	PUNCT
admet-1317	137	4	.	.	PUNCT
admet-1317	138	1	the	the	DET
admet-1317	138	2	following	follow	VERB
admet-1317	138	3	equation	equation	NOUN
admet-1317	138	4	was	be	AUX
admet-1317	138	5	used	use	VERB
admet-1317	138	6	to	to	PART
admet-1317	138	7	estimate	estimate	VERB
admet-1317	138	8	the	the	DET
admet-1317	138	9	primary	primary	ADJ
admet-1317	138	10	irritation	irritation	NOUN
admet-1317	138	11	index	index	NOUN
admet-1317	138	12	(	(	PUNCT
admet-1317	138	13	p.i.i	p.i.i	NOUN
admet-1317	138	14	.	.	PUNCT
admet-1317	138	15	):	):	PUNCT
admet-1317	138	16	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	PROPN
admet-1317	138	17	r.f	r.f	PROPN
admet-1317	138	18	.	.	PROPN
admet-1317	138	19	ghazi	ghazi	PROPN
admet-1317	138	20	and	and	CCONJ
admet-1317	138	21	m.h	m.h	PROPN
admet-1317	138	22	.	.	PROPN
admet-1317	138	23	al	al	PROPN
admet-1317	138	24	-	-	PUNCT
admet-1317	138	25	mayahy	mayahy	PROPN
admet-1317	138	26	admet	admet	PROPN
admet-1317	138	27	&	&	CCONJ
admet-1317	138	28	dmpk	dmpk	PROPN
admet-1317	138	29	10(3	10(3	NUM
admet-1317	138	30	)	)	PUNCT
admet-1317	138	31	(	(	PUNCT
admet-1317	138	32	2022	2022	NUM
admet-1317	138	33	)	)	PUNCT
admet-1317	138	34	213	213	NUM
admet-1317	138	35	-	-	SYM
admet-1317	138	36	230	230	NUM
admet-1317	138	37	218	218	NUM
admet-1317	139	1	p.	p.	NOUN
admet-1317	139	2	𝐼.	𝐼.	PROPN
admet-1317	139	3	𝐼.	𝐼.	PROPN
admet-1317	139	4	=	=	PUNCT
admet-1317	139	5	∑	∑	PUNCT
admet-1317	139	6	erythema	erythema	ADJ
admet-1317	139	7	grade	grade	NOUN
admet-1317	139	8	at	at	ADP
admet-1317	139	9	1	1	NUM
admet-1317	139	10	h,24	h,24	NOUN
admet-1317	139	11	h	h	NOUN
admet-1317	139	12	and	and	CCONJ
admet-1317	139	13	72	72	NUM
admet-1317	139	14	h	h	NOUN
admet-1317	139	15	+	+	CCONJ
admet-1317	139	16	∑	∑	ADJ
admet-1317	139	17	edema	edema	NOUN
admet-1317	139	18	grade	grade	NOUN
admet-1317	139	19	at	at	ADP
admet-1317	139	20	1	1	NUM
admet-1317	139	21	h,24	h,24	NOUN
admet-1317	139	22	h	h	NOUN
admet-1317	139	23	and	and	CCONJ
admet-1317	139	24	72	72	NUM
admet-1317	139	25	h	h	NOUN
admet-1317	139	26	number	number	NOUN
admet-1317	139	27	of	of	ADP
admet-1317	139	28	rats	rat	NOUN
admet-1317	139	29	×	×	NOUN
admet-1317	139	30	number	number	NOUN
admet-1317	139	31	of	of	ADP
admet-1317	139	32	application	application	NOUN
admet-1317	139	33	skin	skin	NOUN
admet-1317	139	34	sites	site	NOUN
admet-1317	139	35	×	×	VERB
admet-1317	139	36	time	time	NOUN
admet-1317	139	37	of	of	ADP
admet-1317	139	38	reading	reading	NOUN
admet-1317	139	39	(	(	PUNCT
admet-1317	139	40	2	2	NUM
admet-1317	139	41	)	)	PUNCT
admet-1317	139	42	draize	draize	VERB
admet-1317	139	43	dermal	dermal	ADJ
admet-1317	139	44	scoring	scoring	NOUN
admet-1317	139	45	criteria	criterion	NOUN
admet-1317	139	46	were	be	AUX
admet-1317	139	47	used	use	VERB
admet-1317	139	48	to	to	PART
admet-1317	139	49	evaluate	evaluate	VERB
admet-1317	139	50	the	the	DET
admet-1317	139	51	irritancy	irritancy	NOUN
admet-1317	139	52	potential	potential	NOUN
admet-1317	139	53	of	of	ADP
admet-1317	139	54	the	the	DET
admet-1317	139	55	mn	mn	PROPN
admet-1317	139	56	arrays	array	VERB
admet-1317	139	57	,	,	PUNCT
admet-1317	139	58	as	as	SCONJ
admet-1317	139	59	described	describe	VERB
admet-1317	139	60	in	in	ADP
admet-1317	139	61	table	table	NOUN
admet-1317	139	62	2	2	NUM
admet-1317	139	63	.	.	PUNCT
admet-1317	140	1	additionally	additionally	ADV
admet-1317	140	2	,	,	PUNCT
admet-1317	140	3	a	a	DET
admet-1317	140	4	traditional	traditional	ADJ
admet-1317	140	5	hypodermic	hypodermic	ADJ
admet-1317	140	6	syringe	syringe	NOUN
admet-1317	140	7	of	of	ADP
admet-1317	140	8	gauge	gauge	NOUN
admet-1317	140	9	23	23	NUM
admet-1317	140	10	g	g	NOUN
admet-1317	140	11	was	be	AUX
admet-1317	140	12	also	also	ADV
admet-1317	140	13	used	use	VERB
admet-1317	140	14	for	for	ADP
admet-1317	140	15	the	the	DET
admet-1317	140	16	comparison	comparison	NOUN
admet-1317	140	17	with	with	ADP
admet-1317	140	18	mns	mns	PROPN
admet-1317	140	19	for	for	ADP
admet-1317	140	20	producing	produce	VERB
admet-1317	140	21	erythema	erythema	NOUN
admet-1317	140	22	and	and	CCONJ
admet-1317	140	23	edema	edema	NOUN
admet-1317	140	24	.	.	PUNCT
admet-1317	141	1	these	these	DET
admet-1317	141	2	irritation	irritation	NOUN
admet-1317	141	3	signs	sign	NOUN
admet-1317	141	4	were	be	AUX
admet-1317	141	5	evaluated	evaluate	VERB
admet-1317	141	6	at	at	ADP
admet-1317	141	7	1	1	NUM
admet-1317	141	8	,	,	PUNCT
admet-1317	141	9	24	24	NUM
admet-1317	141	10	and	and	CCONJ
admet-1317	141	11	72	72	NUM
admet-1317	141	12	hours	hour	NOUN
admet-1317	141	13	using	use	VERB
admet-1317	141	14	a	a	DET
admet-1317	141	15	digital	digital	ADJ
admet-1317	141	16	microscope	microscope	NOUN
admet-1317	141	17	.	.	PUNCT
admet-1317	142	1	table	table	NOUN
admet-1317	142	2	2	2	NUM
admet-1317	142	3	.	.	PUNCT
admet-1317	142	4	draize	draize	VERB
admet-1317	142	5	dermal	dermal	ADJ
admet-1317	142	6	scoring	scoring	NOUN
admet-1317	142	7	criteria	criterion	NOUN
admet-1317	142	8	[	[	X
admet-1317	142	9	27	27	NUM
admet-1317	142	10	]	]	SYM
admet-1317	142	11	:	:	PUNCT
admet-1317	142	12	statistical	statistical	ADJ
admet-1317	142	13	analysis	analysis	NOUN
admet-1317	142	14	was	be	AUX
admet-1317	142	15	carried	carry	VERB
admet-1317	142	16	out	out	ADP
admet-1317	142	17	using	use	VERB
admet-1317	142	18	one	one	NUM
admet-1317	142	19	-	-	PUNCT
admet-1317	142	20	way	way	NOUN
admet-1317	142	21	anova	anova	PROPN
admet-1317	142	22	followed	follow	VERB
admet-1317	142	23	by	by	ADP
admet-1317	142	24	the	the	DET
admet-1317	142	25	tukey	tukey	PROPN
admet-1317	142	26	test	test	NOUN
admet-1317	142	27	to	to	PART
admet-1317	142	28	determine	determine	VERB
admet-1317	142	29	the	the	DET
admet-1317	142	30	presence	presence	NOUN
admet-1317	142	31	of	of	ADP
admet-1317	142	32	any	any	DET
admet-1317	142	33	significant	significant	ADJ
admet-1317	142	34	difference	difference	NOUN
admet-1317	142	35	among	among	ADP
admet-1317	142	36	the	the	DET
admet-1317	142	37	data	datum	NOUN
admet-1317	142	38	.	.	PUNCT
admet-1317	143	1	all	all	DET
admet-1317	143	2	data	datum	NOUN
admet-1317	143	3	are	be	AUX
admet-1317	143	4	presented	present	VERB
admet-1317	143	5	as	as	ADP
admet-1317	143	6	the	the	DET
admet-1317	143	7	mean	mean	ADJ
admet-1317	143	8	±	±	NOUN
admet-1317	143	9	sd	sd	NOUN
admet-1317	143	10	with	with	ADP
admet-1317	143	11	p	p	NOUN
admet-1317	143	12	values	value	NOUN
admet-1317	143	13	of	of	ADP
admet-1317	143	14	≤	≤	NUM
admet-1317	143	15	0.05	0.05	NUM
admet-1317	143	16	being	be	AUX
admet-1317	143	17	regarded	regard	VERB
admet-1317	143	18	as	as	ADP
admet-1317	143	19	statistically	statistically	ADV
admet-1317	143	20	significant	significant	ADJ
admet-1317	143	21	[	[	X
admet-1317	143	22	5	5	NUM
admet-1317	143	23	]	]	PUNCT
admet-1317	143	24	.	.	PUNCT
admet-1317	144	1	results	result	NOUN
admet-1317	144	2	and	and	CCONJ
admet-1317	144	3	discussion	discussion	NOUN
admet-1317	144	4	preparation	preparation	NOUN
admet-1317	144	5	,	,	PUNCT
admet-1317	144	6	visual	visual	ADJ
admet-1317	144	7	inspection	inspection	NOUN
admet-1317	144	8	and	and	CCONJ
admet-1317	144	9	microscopic	microscopic	ADJ
admet-1317	144	10	examination	examination	NOUN
admet-1317	144	11	of	of	ADP
admet-1317	144	12	levothyroxine	levothyroxine	PROPN
admet-1317	144	13	sodium	sodium	NOUN
admet-1317	144	14	loaded	load	VERB
admet-1317	144	15	hyaluronic	hyaluronic	ADJ
admet-1317	144	16	acid	acid	NOUN
admet-1317	144	17	microneedle	microneedle	NOUN
admet-1317	144	18	arrays	array	VERB
admet-1317	144	19	lt-4	lt-4	ADV
admet-1317	144	20	sodium	sodium	NOUN
admet-1317	144	21	-	-	PUNCT
admet-1317	144	22	loaded	load	VERB
admet-1317	144	23	ha	ha	INTJ
admet-1317	144	24	mns	mns	PROPN
admet-1317	144	25	were	be	AUX
admet-1317	144	26	prepared	prepare	VERB
admet-1317	144	27	using	use	VERB
admet-1317	144	28	micromoulding	micromoulde	VERB
admet-1317	144	29	technique	technique	NOUN
admet-1317	144	30	.	.	PUNCT
admet-1317	145	1	ha	ha	INTJ
admet-1317	145	2	was	be	AUX
admet-1317	145	3	used	use	VERB
admet-1317	145	4	as	as	ADP
admet-1317	145	5	a	a	DET
admet-1317	145	6	matrix	matrix	NOUN
admet-1317	145	7	polymer	polymer	NOUN
admet-1317	145	8	in	in	ADP
admet-1317	145	9	this	this	DET
admet-1317	145	10	study	study	NOUN
admet-1317	145	11	for	for	ADP
admet-1317	145	12	reasons	reason	NOUN
admet-1317	145	13	other	other	ADJ
admet-1317	145	14	than	than	ADP
admet-1317	145	15	its	its	PRON
admet-1317	145	16	biocompatibility	biocompatibility	NOUN
admet-1317	145	17	and	and	CCONJ
admet-1317	145	18	biodegradability	biodegradability	NOUN
admet-1317	145	19	;	;	PUNCT
admet-1317	145	20	the	the	DET
admet-1317	145	21	manufacturing	manufacturing	NOUN
admet-1317	145	22	of	of	ADP
admet-1317	145	23	ha	ha	INTJ
admet-1317	145	24	mns	mns	PROPN
admet-1317	145	25	does	do	AUX
admet-1317	145	26	not	not	PART
admet-1317	145	27	necessitate	necessitate	ADJ
admet-1317	145	28	extreme	extreme	ADJ
admet-1317	145	29	conditions	condition	NOUN
admet-1317	145	30	such	such	ADJ
admet-1317	145	31	as	as	ADP
admet-1317	145	32	high	high	ADJ
admet-1317	145	33	temperatures	temperature	NOUN
admet-1317	145	34	or	or	CCONJ
admet-1317	145	35	photolithography	photolithography	NOUN
admet-1317	145	36	.	.	PUNCT
admet-1317	146	1	moreover	moreover	ADV
admet-1317	146	2	,	,	PUNCT
admet-1317	146	3	the	the	DET
admet-1317	146	4	application	application	NOUN
admet-1317	146	5	of	of	ADP
admet-1317	146	6	ha	ha	INTJ
admet-1317	146	7	dissolving	dissolve	VERB
admet-1317	146	8	mns	mns	PROPN
admet-1317	146	9	can	can	AUX
admet-1317	146	10	improve	improve	VERB
admet-1317	146	11	the	the	DET
admet-1317	146	12	transport	transport	NOUN
admet-1317	146	13	of	of	ADP
admet-1317	146	14	active	active	ADJ
admet-1317	146	15	agents	agent	NOUN
admet-1317	146	16	into	into	ADP
admet-1317	146	17	and	and	CCONJ
admet-1317	146	18	through	through	ADP
admet-1317	146	19	the	the	DET
admet-1317	146	20	skin	skin	NOUN
admet-1317	146	21	while	while	SCONJ
admet-1317	146	22	also	also	ADV
admet-1317	146	23	delivering	deliver	VERB
admet-1317	146	24	ha	ha	INTJ
admet-1317	146	25	into	into	ADP
admet-1317	146	26	the	the	DET
admet-1317	146	27	skin	skin	NOUN
admet-1317	146	28	itself	itself	PRON
admet-1317	146	29	as	as	ADP
admet-1317	146	30	an	an	DET
admet-1317	146	31	added	add	VERB
admet-1317	146	32	advantage	advantage	NOUN
admet-1317	146	33	[	[	X
admet-1317	146	34	22	22	NUM
admet-1317	146	35	]	]	PUNCT
admet-1317	146	36	.	.	PUNCT
admet-1317	147	1	as	as	ADP
admet-1317	147	2	a	a	DET
admet-1317	147	3	result	result	NOUN
admet-1317	147	4	,	,	PUNCT
admet-1317	147	5	the	the	DET
admet-1317	147	6	chosen	choose	VERB
admet-1317	147	7	micromoulding	micromoulding	NOUN
admet-1317	147	8	method	method	NOUN
admet-1317	147	9	with	with	ADP
admet-1317	147	10	ha	ha	INTJ
admet-1317	147	11	as	as	ADP
admet-1317	147	12	a	a	DET
admet-1317	147	13	matrix	matrix	NOUN
admet-1317	147	14	polymer	polymer	NOUN
admet-1317	147	15	is	be	AUX
admet-1317	147	16	ideally	ideally	ADV
admet-1317	147	17	suited	suit	VERB
admet-1317	147	18	for	for	ADP
admet-1317	147	19	incorporating	incorporate	VERB
admet-1317	147	20	heat	heat	NOUN
admet-1317	147	21	and	and	CCONJ
admet-1317	147	22	photosensitive	photosensitive	ADJ
admet-1317	147	23	molecules	molecule	NOUN
admet-1317	147	24	such	such	ADJ
admet-1317	147	25	as	as	ADP
admet-1317	147	26	lt-4	lt-4	ADJ
admet-1317	147	27	sodium	sodium	NOUN
admet-1317	147	28	into	into	ADP
admet-1317	147	29	mns	mns	PROPN
admet-1317	148	1	[	[	X
admet-1317	148	2	28	28	NUM
admet-1317	148	3	]	]	PUNCT
admet-1317	148	4	.	.	PUNCT
admet-1317	149	1	not	not	PART
admet-1317	149	2	only	only	ADV
admet-1317	149	3	does	do	AUX
admet-1317	149	4	the	the	DET
admet-1317	149	5	mns	mns	PROPN
admet-1317	149	6	matrix	matrix	NOUN
admet-1317	149	7	material	material	NOUN
admet-1317	149	8	affect	affect	VERB
admet-1317	149	9	the	the	DET
admet-1317	149	10	effectiveness	effectiveness	NOUN
admet-1317	149	11	of	of	ADP
admet-1317	149	12	the	the	DET
admet-1317	149	13	mns	mns	PROPN
admet-1317	149	14	,	,	PUNCT
admet-1317	149	15	but	but	CCONJ
admet-1317	149	16	it	it	PRON
admet-1317	149	17	also	also	ADV
admet-1317	149	18	does	do	VERB
admet-1317	149	19	the	the	DET
admet-1317	149	20	geometry	geometry	NOUN
admet-1317	149	21	of	of	ADP
admet-1317	149	22	mns	mns	PROPN
admet-1317	149	23	.	.	PUNCT
admet-1317	150	1	in	in	ADP
admet-1317	150	2	case	case	NOUN
admet-1317	150	3	the	the	DET
admet-1317	150	4	needle	needle	NOUN
admet-1317	150	5	arrays	array	VERB
admet-1317	150	6	were	be	AUX
admet-1317	150	7	too	too	ADV
admet-1317	150	8	close	close	ADJ
admet-1317	150	9	together	together	ADV
admet-1317	150	10	,	,	PUNCT
admet-1317	150	11	a	a	DET
admet-1317	150	12	"	"	PUNCT
admet-1317	150	13	bed	bed	NOUN
admet-1317	150	14	of	of	ADP
admet-1317	150	15	nails	nail	NOUN
admet-1317	150	16	"	"	PUNCT
admet-1317	150	17	situation	situation	NOUN
admet-1317	150	18	occurs	occur	VERB
admet-1317	150	19	,	,	PUNCT
admet-1317	150	20	resulting	result	VERB
admet-1317	150	21	in	in	ADP
admet-1317	150	22	penetration	penetration	NOUN
admet-1317	150	23	failure	failure	NOUN
admet-1317	150	24	[	[	X
admet-1317	150	25	29	29	NUM
admet-1317	150	26	]	]	PUNCT
admet-1317	150	27	.	.	PUNCT
admet-1317	151	1	furthermore	furthermore	ADV
admet-1317	151	2	,	,	PUNCT
admet-1317	151	3	numerous	numerous	ADJ
admet-1317	151	4	publications	publication	NOUN
admet-1317	151	5	in	in	ADP
admet-1317	151	6	the	the	DET
admet-1317	151	7	literature	literature	NOUN
admet-1317	151	8	have	have	AUX
admet-1317	151	9	linked	link	VERB
admet-1317	151	10	the	the	DET
admet-1317	151	11	shape	shape	NOUN
admet-1317	151	12	of	of	ADP
admet-1317	151	13	needles	needle	NOUN
admet-1317	151	14	ranging	range	VERB
admet-1317	151	15	from	from	ADP
admet-1317	151	16	conical	conical	NOUN
admet-1317	151	17	,	,	PUNCT
admet-1317	151	18	octagonal	octagonal	ADJ
admet-1317	151	19	,	,	PUNCT
admet-1317	151	20	rectangular	rectangular	ADJ
admet-1317	151	21	,	,	PUNCT
admet-1317	151	22	cylindrical	cylindrical	ADJ
admet-1317	151	23	and	and	CCONJ
admet-1317	151	24	pyramidal	pyramidal	NOUN
admet-1317	151	25	to	to	ADP
admet-1317	151	26	the	the	DET
admet-1317	151	27	required	require	VERB
admet-1317	151	28	penetration	penetration	NOUN
admet-1317	151	29	force	force	NOUN
admet-1317	151	30	[	[	X
admet-1317	151	31	30	30	NUM
admet-1317	151	32	]	]	PUNCT
admet-1317	151	33	.	.	PUNCT
admet-1317	152	1	typically	typically	ADV
admet-1317	152	2	,	,	PUNCT
admet-1317	152	3	a	a	DET
admet-1317	152	4	pyramidal	pyramidal	ADJ
admet-1317	152	5	shape	shape	NOUN
admet-1317	152	6	exerted	exert	VERB
admet-1317	152	7	the	the	DET
admet-1317	152	8	greatest	great	ADJ
admet-1317	152	9	puncture	puncture	NOUN
admet-1317	152	10	strength	strength	NOUN
admet-1317	152	11	,	,	PUNCT
admet-1317	152	12	making	make	VERB
admet-1317	152	13	application	application	NOUN
admet-1317	152	14	easier	easy	ADJ
admet-1317	152	15	[	[	X
admet-1317	152	16	5	5	NUM
admet-1317	152	17	]	]	PUNCT
admet-1317	152	18	.	.	PUNCT
admet-1317	153	1	the	the	DET
admet-1317	153	2	pyramidal	pyramidal	ADJ
admet-1317	153	3	design	design	NOUN
admet-1317	153	4	,	,	PUNCT
admet-1317	153	5	according	accord	VERB
admet-1317	153	6	to	to	ADP
admet-1317	153	7	laue	laue	PROPN
admet-1317	153	8	et	et	PROPN
admet-1317	153	9	al	al	PROPN
admet-1317	153	10	.	.	PROPN
admet-1317	153	11	,	,	PUNCT
admet-1317	153	12	enabled	enable	VERB
admet-1317	153	13	increased	increase	VERB
admet-1317	153	14	drug	drug	NOUN
admet-1317	153	15	release	release	NOUN
admet-1317	153	16	by	by	ADP
admet-1317	153	17	expanding	expand	VERB
admet-1317	153	18	the	the	DET
admet-1317	153	19	contact	contact	NOUN
admet-1317	153	20	area	area	NOUN
admet-1317	153	21	with	with	ADP
admet-1317	153	22	skin	skin	NOUN
admet-1317	153	23	[	[	X
admet-1317	153	24	31	31	NUM
admet-1317	153	25	]	]	PUNCT
admet-1317	153	26	.	.	PUNCT
admet-1317	154	1	in	in	ADP
admet-1317	154	2	this	this	DET
admet-1317	154	3	study	study	NOUN
admet-1317	154	4	,	,	PUNCT
admet-1317	154	5	ha	ha	INTJ
admet-1317	154	6	was	be	AUX
admet-1317	154	7	used	use	VERB
admet-1317	154	8	in	in	ADP
admet-1317	154	9	different	different	ADJ
admet-1317	154	10	ratios	ratio	NOUN
admet-1317	154	11	ranging	range	VERB
admet-1317	154	12	from	from	ADP
admet-1317	154	13	5	5	NUM
admet-1317	154	14	%	%	NOUN
admet-1317	154	15	to	to	PART
admet-1317	154	16	60	60	NUM
admet-1317	154	17	%	%	NOUN
admet-1317	154	18	w	w	NOUN
admet-1317	154	19	/	/	SYM
admet-1317	154	20	v	v	NOUN
admet-1317	154	21	to	to	PART
admet-1317	154	22	investigate	investigate	VERB
admet-1317	154	23	the	the	DET
admet-1317	154	24	appropriate	appropriate	ADJ
admet-1317	154	25	percentage	percentage	NOUN
admet-1317	154	26	for	for	ADP
admet-1317	154	27	producing	produce	VERB
admet-1317	154	28	mns	mns	PROPN
admet-1317	154	29	with	with	ADP
admet-1317	154	30	sufficient	sufficient	ADJ
admet-1317	154	31	mechanical	mechanical	ADJ
admet-1317	154	32	strength	strength	NOUN
admet-1317	154	33	required	require	VERB
admet-1317	154	34	for	for	ADP
admet-1317	154	35	effective	effective	ADJ
admet-1317	154	36	penetration	penetration	NOUN
admet-1317	154	37	into	into	ADP
admet-1317	154	38	the	the	DET
admet-1317	154	39	skin	skin	NOUN
admet-1317	154	40	.	.	PUNCT
admet-1317	155	1	the	the	DET
admet-1317	155	2	drying	dry	VERB
admet-1317	155	3	time	time	NOUN
admet-1317	155	4	is	be	AUX
admet-1317	155	5	also	also	ADV
admet-1317	155	6	a	a	DET
admet-1317	155	7	crucial	crucial	ADJ
admet-1317	155	8	consideration	consideration	NOUN
admet-1317	155	9	in	in	ADP
admet-1317	155	10	mns	mns	PROPN
admet-1317	155	11	manufacturing	manufacturing	NOUN
admet-1317	155	12	affecting	affect	VERB
admet-1317	155	13	the	the	DET
admet-1317	155	14	needle	needle	NOUN
admet-1317	155	15	shape	shape	NOUN
admet-1317	155	16	and	and	CCONJ
admet-1317	155	17	the	the	DET
admet-1317	155	18	mechanical	mechanical	ADJ
admet-1317	155	19	strength	strength	NOUN
admet-1317	155	20	[	[	X
admet-1317	155	21	32	32	NUM
admet-1317	155	22	]	]	PUNCT
admet-1317	155	23	.	.	PUNCT
admet-1317	156	1	the	the	DET
admet-1317	156	2	drying	dry	VERB
admet-1317	156	3	time	time	NOUN
admet-1317	156	4	varies	vary	VERB
admet-1317	156	5	relatively	relatively	ADV
admet-1317	156	6	depending	depend	VERB
admet-1317	156	7	on	on	ADP
admet-1317	156	8	the	the	DET
admet-1317	156	9	concentration	concentration	NOUN
admet-1317	156	10	of	of	ADP
admet-1317	156	11	ha	ha	INTJ
admet-1317	156	12	.	.	PUNCT
admet-1317	157	1	in	in	ADP
admet-1317	157	2	general	general	ADJ
admet-1317	157	3	,	,	PUNCT
admet-1317	157	4	24	24	NUM
admet-1317	157	5	hours	hour	NOUN
admet-1317	157	6	were	be	AUX
admet-1317	157	7	required	require	VERB
admet-1317	157	8	to	to	PART
admet-1317	157	9	obtain	obtain	VERB
admet-1317	157	10	completely	completely	ADV
admet-1317	157	11	dry	dry	ADJ
admet-1317	157	12	mn	mn	PROPN
admet-1317	157	13	arrays	array	VERB
admet-1317	157	14	in	in	ADP
admet-1317	157	15	this	this	DET
admet-1317	157	16	study	study	NOUN
admet-1317	157	17	which	which	PRON
admet-1317	157	18	is	be	AUX
admet-1317	157	19	a	a	DET
admet-1317	157	20	suitable	suitable	ADJ
admet-1317	157	21	duration	duration	NOUN
admet-1317	157	22	of	of	ADP
admet-1317	157	23	time	time	NOUN
admet-1317	157	24	to	to	PART
admet-1317	157	25	be	be	AUX
admet-1317	157	26	fitted	fit	VERB
admet-1317	157	27	with	with	ADP
admet-1317	157	28	the	the	DET
admet-1317	157	29	large	large	ADJ
admet-1317	157	30	-	-	PUNCT
admet-1317	157	31	scale	scale	NOUN
admet-1317	157	32	production	production	NOUN
admet-1317	157	33	.	.	PUNCT
admet-1317	158	1	total	total	ADJ
admet-1317	158	2	dryness	dryness	NOUN
admet-1317	158	3	of	of	ADP
admet-1317	158	4	the	the	DET
admet-1317	158	5	mns	mns	PROPN
admet-1317	158	6	was	be	AUX
admet-1317	158	7	required	require	VERB
admet-1317	158	8	to	to	PART
admet-1317	158	9	guarantee	guarantee	VERB
admet-1317	158	10	adequate	adequate	ADJ
admet-1317	158	11	mechanical	mechanical	ADJ
admet-1317	158	12	strength	strength	NOUN
admet-1317	159	1	[	[	X
admet-1317	159	2	23	23	NUM
admet-1317	159	3	]	]	PUNCT
admet-1317	159	4	.	.	PUNCT
admet-1317	160	1	on	on	ADP
admet-1317	160	2	the	the	DET
admet-1317	160	3	other	other	ADJ
admet-1317	160	4	hand	hand	NOUN
admet-1317	160	5	,	,	PUNCT
admet-1317	160	6	inappropriate	inappropriate	ADJ
admet-1317	160	7	drying	dry	VERB
admet-1317	160	8	conditions	condition	NOUN
admet-1317	160	9	led	lead	VERB
admet-1317	160	10	to	to	ADP
admet-1317	160	11	wet	wet	PROPN
admet-1317	160	12	mn	mn	PROPN
admet-1317	160	13	arrays	array	VERB
admet-1317	160	14	,	,	PUNCT
admet-1317	160	15	which	which	PRON
admet-1317	160	16	bent	bend	VERB
admet-1317	160	17	when	when	SCONJ
admet-1317	160	18	removed	remove	VERB
admet-1317	160	19	from	from	ADP
admet-1317	160	20	the	the	DET
admet-1317	160	21	mould	mould	NOUN
admet-1317	160	22	resulting	result	VERB
admet-1317	160	23	in	in	ADP
admet-1317	160	24	unsatisfactory	unsatisfactory	ADJ
admet-1317	160	25	skin	skin	NOUN
admet-1317	160	26	penetration	penetration	NOUN
admet-1317	160	27	capabilities	capability	NOUN
admet-1317	160	28	.	.	PUNCT
admet-1317	161	1	tween	tween	NOUN
admet-1317	161	2	80	80	NUM
admet-1317	161	3	was	be	AUX
admet-1317	161	4	added	add	VERB
admet-1317	161	5	to	to	PART
admet-1317	161	6	enhance	enhance	VERB
admet-1317	161	7	the	the	DET
admet-1317	161	8	solubility	solubility	NOUN
admet-1317	161	9	of	of	ADP
admet-1317	161	10	lt4	lt4	PROPN
admet-1317	161	11	sodium	sodium	PROPN
admet-1317	161	12	.	.	PUNCT
admet-1317	162	1	in	in	ADP
admet-1317	162	2	addition	addition	NOUN
admet-1317	162	3	to	to	ADP
admet-1317	162	4	enhancing	enhance	VERB
admet-1317	162	5	solubility	solubility	NOUN
admet-1317	162	6	,	,	PUNCT
admet-1317	162	7	tween	tween	NOUN
admet-1317	162	8	80	80	NUM
admet-1317	162	9	plays	play	VERB
admet-1317	162	10	a	a	DET
admet-1317	162	11	role	role	NOUN
admet-1317	162	12	in	in	ADP
admet-1317	162	13	p.i.i	p.i.i	NOUN
admet-1317	162	14	.	.	PUNCT
admet-1317	163	1	classification	classification	NOUN
admet-1317	163	2	0.0	0.0	NUM
admet-1317	163	3	0.4	0.4	NUM
admet-1317	163	4	no	no	DET
admet-1317	163	5	irritation	irritation	NOUN
admet-1317	163	6	0.5	0.5	NUM
admet-1317	163	7	1.9	1.9	NUM
admet-1317	163	8	slight	slight	ADJ
admet-1317	163	9	irritation	irritation	NOUN
admet-1317	163	10	2.0	2.0	NUM
admet-1317	163	11	4.9	4.9	NUM
admet-1317	163	12	moderate	moderate	ADJ
admet-1317	163	13	irritation	irritation	NOUN
admet-1317	163	14	5.0	5.0	NUM
admet-1317	163	15	8.0	8.0	NUM
admet-1317	163	16	sever	sever	VERB
admet-1317	163	17	irritation	irritation	NOUN
admet-1317	163	18	admet	admet	NOUN
admet-1317	163	19	&	&	CCONJ
admet-1317	163	20	dmpk	dmpk	PROPN
admet-1317	163	21	10(3	10(3	NUM
admet-1317	163	22	)	)	PUNCT
admet-1317	163	23	(	(	PUNCT
admet-1317	163	24	2022	2022	NUM
admet-1317	163	25	)	)	PUNCT
admet-1317	163	26	213	213	NUM
admet-1317	163	27	-	-	SYM
admet-1317	163	28	230	230	NUM
admet-1317	163	29	transdermal	transdermal	ADJ
admet-1317	163	30	delivery	delivery	NOUN
admet-1317	163	31	of	of	ADP
admet-1317	163	32	levothyroxine	levothyroxine	NOUN
admet-1317	163	33	via	via	ADP
admet-1317	163	34	dissolving	dissolve	VERB
admet-1317	163	35	microneedles	microneedle	NOUN
admet-1317	163	36	doi	doi	PROPN
admet-1317	163	37	:	:	PUNCT
admet-1317	163	38	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	NUM
admet-1317	163	39	219	219	NUM
admet-1317	163	40	providing	provide	VERB
admet-1317	163	41	the	the	DET
admet-1317	163	42	formulation	formulation	NOUN
admet-1317	163	43	with	with	ADP
admet-1317	163	44	the	the	DET
admet-1317	163	45	required	require	VERB
admet-1317	163	46	elasticity	elasticity	NOUN
admet-1317	163	47	necessary	necessary	ADJ
admet-1317	163	48	for	for	ADP
admet-1317	163	49	the	the	DET
admet-1317	163	50	easy	easy	ADJ
admet-1317	163	51	removal	removal	NOUN
admet-1317	163	52	of	of	ADP
admet-1317	163	53	mns	mns	PROPN
admet-1317	163	54	from	from	ADP
admet-1317	163	55	the	the	DET
admet-1317	163	56	mould	mould	NOUN
admet-1317	163	57	without	without	ADP
admet-1317	163	58	any	any	DET
admet-1317	163	59	fracture	fracture	NOUN
admet-1317	163	60	.	.	PUNCT
admet-1317	164	1	formulations	formulation	NOUN
admet-1317	164	2	of	of	ADP
admet-1317	164	3	f1	f1	NOUN
admet-1317	164	4	and	and	CCONJ
admet-1317	164	5	f2	f2	PRON
admet-1317	164	6	with	with	ADP
admet-1317	164	7	a	a	DET
admet-1317	164	8	smaller	small	ADJ
admet-1317	164	9	concentration	concentration	NOUN
admet-1317	164	10	5	5	NUM
admet-1317	164	11	%	%	NOUN
admet-1317	164	12	w	w	PROPN
admet-1317	164	13	/	/	SYM
admet-1317	164	14	v	v	NOUN
admet-1317	164	15	of	of	ADP
admet-1317	164	16	ha	ha	INTJ
admet-1317	164	17	containing	contain	VERB
admet-1317	164	18	1	1	NUM
admet-1317	164	19	%	%	NOUN
admet-1317	164	20	v	v	ADP
admet-1317	164	21	/	/	SYM
admet-1317	164	22	v	v	NOUN
admet-1317	164	23	and	and	CCONJ
admet-1317	164	24	2	2	NUM
admet-1317	164	25	%	%	NOUN
admet-1317	164	26	v	v	NOUN
admet-1317	164	27	/	/	SYM
admet-1317	164	28	v	v	NOUN
admet-1317	164	29	of	of	ADP
admet-1317	164	30	tween	tween	NOUN
admet-1317	164	31	80	80	NUM
admet-1317	164	32	,	,	PUNCT
admet-1317	164	33	respectively	respectively	ADV
admet-1317	164	34	,	,	PUNCT
admet-1317	164	35	resulted	result	VERB
admet-1317	164	36	in	in	ADP
admet-1317	164	37	soft	soft	ADJ
admet-1317	164	38	,	,	PUNCT
admet-1317	164	39	elastic	elastic	ADJ
admet-1317	164	40	formulations	formulation	NOUN
admet-1317	164	41	with	with	ADP
admet-1317	164	42	a	a	DET
admet-1317	164	43	gummy	gummy	ADJ
admet-1317	164	44	texture	texture	NOUN
admet-1317	164	45	that	that	PRON
admet-1317	164	46	are	be	AUX
admet-1317	164	47	unsuitable	unsuitable	ADJ
admet-1317	164	48	for	for	ADP
admet-1317	164	49	the	the	DET
admet-1317	164	50	mns	mns	PROPN
admet-1317	164	51	formation	formation	NOUN
admet-1317	164	52	.	.	PUNCT
admet-1317	165	1	formulas	formula	NOUN
admet-1317	165	2	from	from	ADP
admet-1317	165	3	f3	f3	PROPN
admet-1317	165	4	to	to	ADP
admet-1317	165	5	f11	f11	PROPN
admet-1317	165	6	have	have	AUX
admet-1317	165	7	resulted	result	VERB
admet-1317	165	8	in	in	ADP
admet-1317	165	9	the	the	DET
admet-1317	165	10	formation	formation	NOUN
admet-1317	165	11	of	of	ADP
admet-1317	165	12	elegant	elegant	ADJ
admet-1317	165	13	shaped	shape	VERB
admet-1317	165	14	mn	mn	PROPN
admet-1317	165	15	arrays	array	VERB
admet-1317	165	16	that	that	PRON
admet-1317	165	17	are	be	AUX
admet-1317	165	18	fully	fully	ADV
admet-1317	165	19	formed	form	VERB
admet-1317	165	20	.	.	PUNCT
admet-1317	166	1	a	a	DET
admet-1317	166	2	digital	digital	ADJ
admet-1317	166	3	microscope	microscope	NOUN
admet-1317	166	4	was	be	AUX
admet-1317	166	5	used	use	VERB
admet-1317	166	6	for	for	ADP
admet-1317	166	7	the	the	DET
admet-1317	166	8	visualization	visualization	NOUN
admet-1317	166	9	of	of	ADP
admet-1317	166	10	the	the	DET
admet-1317	166	11	fabricated	fabricate	VERB
admet-1317	166	12	mns	mns	PROPN
admet-1317	166	13	as	as	SCONJ
admet-1317	166	14	illustrated	illustrate	VERB
admet-1317	166	15	in	in	ADP
admet-1317	166	16	figure	figure	NOUN
admet-1317	166	17	1	1	NUM
admet-1317	166	18	.	.	PUNCT
admet-1317	166	19	f12	f12	NOUN
admet-1317	166	20	and	and	CCONJ
admet-1317	166	21	f13	f13	ADJ
admet-1317	166	22	formulas	formula	NOUN
admet-1317	166	23	containing	contain	VERB
admet-1317	166	24	55	55	NUM
admet-1317	166	25	%	%	NOUN
admet-1317	166	26	and	and	CCONJ
admet-1317	166	27	60	60	NUM
admet-1317	166	28	%	%	NOUN
admet-1317	166	29	w	w	NOUN
admet-1317	166	30	/	/	SYM
admet-1317	166	31	v	v	NOUN
admet-1317	166	32	of	of	ADP
admet-1317	166	33	ha	ha	INTJ
admet-1317	166	34	,	,	PUNCT
admet-1317	166	35	respectively	respectively	ADV
admet-1317	166	36	,	,	PUNCT
admet-1317	166	37	did	do	AUX
admet-1317	166	38	not	not	PART
admet-1317	166	39	result	result	VERB
admet-1317	166	40	in	in	ADP
admet-1317	166	41	fully	fully	ADV
admet-1317	166	42	formed	form	VERB
admet-1317	166	43	mns	mns	PROPN
admet-1317	166	44	.	.	PUNCT
admet-1317	167	1	this	this	PRON
admet-1317	167	2	can	can	AUX
admet-1317	167	3	be	be	AUX
admet-1317	167	4	attributed	attribute	VERB
admet-1317	167	5	to	to	ADP
admet-1317	167	6	the	the	DET
admet-1317	167	7	polymeric	polymeric	ADJ
admet-1317	167	8	solution	solution	NOUN
admet-1317	167	9	used	use	VERB
admet-1317	167	10	,	,	PUNCT
admet-1317	167	11	which	which	PRON
admet-1317	167	12	was	be	AUX
admet-1317	167	13	too	too	ADV
admet-1317	167	14	viscous	viscous	ADJ
admet-1317	167	15	to	to	PART
admet-1317	167	16	fill	fill	VERB
admet-1317	167	17	the	the	DET
admet-1317	167	18	micronsized	micronsized	ADJ
admet-1317	167	19	cavities	cavity	NOUN
admet-1317	167	20	in	in	ADP
admet-1317	167	21	the	the	DET
admet-1317	167	22	mould	mould	NOUN
admet-1317	167	23	and	and	CCONJ
admet-1317	167	24	therefore	therefore	ADV
admet-1317	167	25	a	a	DET
admet-1317	167	26	limited	limited	ADJ
admet-1317	167	27	number	number	NOUN
admet-1317	167	28	of	of	ADP
admet-1317	167	29	needles	needle	NOUN
admet-1317	167	30	were	be	AUX
admet-1317	167	31	eventually	eventually	ADV
admet-1317	167	32	formed	form	VERB
admet-1317	167	33	.	.	PUNCT
admet-1317	168	1	figure	figure	VERB
admet-1317	168	2	1	1	NUM
admet-1317	168	3	.	.	PUNCT
admet-1317	169	1	digital	digital	ADJ
admet-1317	169	2	microscope	microscope	NOUN
admet-1317	169	3	images	image	NOUN
admet-1317	169	4	of	of	ADP
admet-1317	169	5	mn	mn	PROPN
admet-1317	169	6	arrays	array	VERB
admet-1317	169	7	prepared	prepared	ADJ
admet-1317	169	8	using	use	VERB
admet-1317	169	9	different	different	ADJ
admet-1317	169	10	ratios	ratio	NOUN
admet-1317	169	11	of	of	ADP
admet-1317	169	12	ha	ha	INTJ
admet-1317	169	13	,	,	PUNCT
admet-1317	169	14	where	where	SCONJ
admet-1317	169	15	(	(	PUNCT
admet-1317	169	16	a	a	NOUN
admet-1317	169	17	)	)	PUNCT
admet-1317	169	18	and	and	CCONJ
admet-1317	169	19	(	(	PUNCT
admet-1317	169	20	b	b	X
admet-1317	169	21	)	)	PUNCT
admet-1317	169	22	represent	represent	VERB
admet-1317	169	23	f1	f1	NOUN
admet-1317	169	24	,	,	PUNCT
admet-1317	169	25	(	(	PUNCT
admet-1317	169	26	c	c	X
admet-1317	169	27	)	)	PUNCT
admet-1317	169	28	f2	f2	PROPN
admet-1317	169	29	,	,	PUNCT
admet-1317	169	30	(	(	PUNCT
admet-1317	169	31	d	d	NOUN
admet-1317	169	32	)	)	PUNCT
admet-1317	169	33	f3	f3	ADJ
admet-1317	169	34	,	,	PUNCT
admet-1317	169	35	(	(	PUNCT
admet-1317	169	36	e	e	NOUN
admet-1317	169	37	)	)	PUNCT
admet-1317	169	38	f4	f4	PROPN
admet-1317	169	39	,	,	PUNCT
admet-1317	169	40	(	(	PUNCT
admet-1317	169	41	f	f	X
admet-1317	169	42	)	)	PUNCT
admet-1317	169	43	f5	f5	NOUN
admet-1317	169	44	,	,	PUNCT
admet-1317	169	45	(	(	PUNCT
admet-1317	169	46	g	g	NOUN
admet-1317	169	47	)	)	PUNCT
admet-1317	169	48	f6	f6	PROPN
admet-1317	169	49	,	,	PUNCT
admet-1317	169	50	(	(	PUNCT
admet-1317	169	51	h	h	NOUN
admet-1317	169	52	)	)	PUNCT
admet-1317	169	53	f7	f7	PROPN
admet-1317	169	54	,	,	PUNCT
admet-1317	169	55	(	(	PUNCT
admet-1317	169	56	i	i	NOUN
admet-1317	169	57	)	)	PUNCT
admet-1317	169	58	f8	f8	PROPN
admet-1317	169	59	,	,	PUNCT
admet-1317	169	60	(	(	PUNCT
admet-1317	169	61	j	j	PROPN
admet-1317	169	62	)	)	PUNCT
admet-1317	169	63	f9	f9	PROPN
admet-1317	169	64	,	,	PUNCT
admet-1317	169	65	(	(	PUNCT
admet-1317	169	66	k	k	NOUN
admet-1317	169	67	)	)	PUNCT
admet-1317	169	68	f10	f10	NOUN
admet-1317	169	69	,	,	PUNCT
admet-1317	169	70	(	(	PUNCT
admet-1317	169	71	l	l	NOUN
admet-1317	169	72	)	)	PUNCT
admet-1317	169	73	f11	f11	NOUN
admet-1317	169	74	,	,	PUNCT
admet-1317	169	75	(	(	PUNCT
admet-1317	169	76	m	m	NOUN
admet-1317	169	77	)	)	PUNCT
admet-1317	169	78	f12	f12	NOUN
admet-1317	169	79	and	and	CCONJ
admet-1317	169	80	(	(	PUNCT
admet-1317	169	81	n	n	CCONJ
admet-1317	169	82	)	)	PUNCT
admet-1317	169	83	f13	f13	X
admet-1317	170	1	.	.	PROPN
admet-1317	170	2	characterisation	characterisation	NOUN
admet-1317	170	3	of	of	ADP
admet-1317	170	4	ha	ha	INTJ
admet-1317	170	5	microneedle	microneedle	PROPN
admet-1317	170	6	arrays	array	VERB
admet-1317	170	7	containing	contain	VERB
admet-1317	170	8	lt-4	lt-4	NOUN
admet-1317	170	9	sodium	sodium	NOUN
admet-1317	170	10	measurement	measurement	NOUN
admet-1317	170	11	of	of	ADP
admet-1317	170	12	the	the	DET
admet-1317	170	13	weight	weight	NOUN
admet-1317	170	14	and	and	CCONJ
admet-1317	170	15	thickness	thickness	NOUN
admet-1317	170	16	of	of	ADP
admet-1317	170	17	the	the	DET
admet-1317	170	18	microneedle	microneedle	NOUN
admet-1317	170	19	arrays	array	VERB
admet-1317	170	20	.	.	PUNCT
admet-1317	171	1	the	the	DET
admet-1317	171	2	mn	mn	PROPN
admet-1317	171	3	arrays	array	VERB
admet-1317	171	4	demonstrated	demonstrate	VERB
admet-1317	171	5	a	a	DET
admet-1317	171	6	weight	weight	NOUN
admet-1317	171	7	range	range	NOUN
admet-1317	171	8	of	of	ADP
admet-1317	171	9	(	(	PUNCT
admet-1317	171	10	4	4	NUM
admet-1317	171	11	55	55	NUM
admet-1317	171	12	mg	mg	NOUN
admet-1317	171	13	)	)	PUNCT
admet-1317	171	14	depending	depend	VERB
admet-1317	171	15	largely	largely	ADV
admet-1317	171	16	on	on	ADP
admet-1317	171	17	the	the	DET
admet-1317	171	18	amount	amount	NOUN
admet-1317	171	19	of	of	ADP
admet-1317	171	20	ha	ha	INTJ
admet-1317	171	21	added	add	VERB
admet-1317	171	22	.	.	PUNCT
admet-1317	172	1	the	the	DET
admet-1317	172	2	thickness	thickness	NOUN
admet-1317	172	3	values	value	NOUN
admet-1317	172	4	were	be	AUX
admet-1317	172	5	in	in	ADP
admet-1317	172	6	the	the	DET
admet-1317	172	7	range	range	NOUN
admet-1317	172	8	of	of	ADP
admet-1317	172	9	(	(	PUNCT
admet-1317	172	10	1.01	1.01	NUM
admet-1317	172	11	–	–	SYM
admet-1317	172	12	1.04	1.04	NUM
admet-1317	172	13	mm	mm	NOUN
admet-1317	172	14	)	)	PUNCT
admet-1317	172	15	.	.	PUNCT
admet-1317	173	1	thus	thus	ADV
admet-1317	173	2	,	,	PUNCT
admet-1317	173	3	the	the	DET
admet-1317	173	4	mn	mn	PROPN
admet-1317	173	5	arrays	array	VERB
admet-1317	173	6	possess	possess	VERB
admet-1317	173	7	a	a	DET
admet-1317	173	8	lightweight	lightweight	ADJ
admet-1317	173	9	and	and	CCONJ
admet-1317	173	10	delicate	delicate	ADJ
admet-1317	173	11	thickness	thickness	NOUN
admet-1317	173	12	suitable	suitable	ADJ
admet-1317	173	13	for	for	ADP
admet-1317	173	14	convenient	convenient	ADJ
admet-1317	173	15	use	use	NOUN
admet-1317	173	16	by	by	ADP
admet-1317	173	17	the	the	DET
admet-1317	173	18	patients	patient	NOUN
admet-1317	173	19	.	.	PUNCT
admet-1317	174	1	detailed	detailed	ADJ
admet-1317	174	2	results	result	NOUN
admet-1317	174	3	regarding	regard	VERB
admet-1317	174	4	the	the	DET
admet-1317	174	5	weight	weight	NOUN
admet-1317	174	6	and	and	CCONJ
admet-1317	174	7	thickness	thickness	NOUN
admet-1317	174	8	of	of	ADP
admet-1317	174	9	each	each	DET
admet-1317	174	10	formula	formula	NOUN
admet-1317	174	11	are	be	AUX
admet-1317	174	12	shown	show	VERB
admet-1317	174	13	in	in	ADP
admet-1317	174	14	the	the	DET
admet-1317	174	15	supplementary	supplementary	ADJ
admet-1317	174	16	materials	material	NOUN
admet-1317	174	17	.	.	PUNCT
admet-1317	175	1	assessment	assessment	NOUN
admet-1317	175	2	of	of	ADP
admet-1317	175	3	the	the	DET
admet-1317	175	4	mechanical	mechanical	ADJ
admet-1317	175	5	properties	property	NOUN
admet-1317	175	6	of	of	ADP
admet-1317	175	7	microneedle	microneedle	NOUN
admet-1317	175	8	arrays	array	VERB
admet-1317	175	9	.	.	PUNCT
admet-1317	176	1	to	to	PART
admet-1317	176	2	allow	allow	VERB
admet-1317	176	3	consistent	consistent	ADJ
admet-1317	176	4	application	application	NOUN
admet-1317	176	5	and	and	CCONJ
admet-1317	176	6	drug	drug	NOUN
admet-1317	176	7	delivery	delivery	NOUN
admet-1317	176	8	,	,	PUNCT
admet-1317	176	9	mns	mns	PROPN
admet-1317	176	10	must	must	AUX
admet-1317	176	11	be	be	AUX
admet-1317	176	12	inserted	insert	VERB
admet-1317	176	13	into	into	ADP
admet-1317	176	14	the	the	DET
admet-1317	176	15	skin	skin	NOUN
admet-1317	176	16	without	without	ADP
admet-1317	176	17	failure	failure	NOUN
admet-1317	176	18	[	[	X
admet-1317	176	19	33	33	NUM
admet-1317	176	20	]	]	PUNCT
admet-1317	176	21	.	.	PUNCT
admet-1317	177	1	the	the	DET
admet-1317	177	2	mechanical	mechanical	ADJ
admet-1317	177	3	strength	strength	NOUN
admet-1317	177	4	of	of	ADP
admet-1317	177	5	the	the	DET
admet-1317	177	6	prepared	prepared	PROPN
admet-1317	177	7	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	X
admet-1317	177	8	r.f	r.f	PROPN
admet-1317	177	9	.	.	PROPN
admet-1317	177	10	ghazi	ghazi	PROPN
admet-1317	177	11	and	and	CCONJ
admet-1317	177	12	m.h	m.h	PROPN
admet-1317	177	13	.	.	PROPN
admet-1317	177	14	al	al	PROPN
admet-1317	177	15	-	-	PUNCT
admet-1317	177	16	mayahy	mayahy	PROPN
admet-1317	177	17	admet	admet	PROPN
admet-1317	177	18	&	&	CCONJ
admet-1317	177	19	dmpk	dmpk	PROPN
admet-1317	177	20	10(3	10(3	NUM
admet-1317	177	21	)	)	PUNCT
admet-1317	177	22	(	(	PUNCT
admet-1317	177	23	2022	2022	NUM
admet-1317	177	24	)	)	PUNCT
admet-1317	177	25	213	213	NUM
admet-1317	177	26	-	-	SYM
admet-1317	177	27	230	230	NUM
admet-1317	177	28	220	220	NUM
admet-1317	177	29	dissolving	dissolve	VERB
admet-1317	177	30	mns	mns	PROPN
admet-1317	177	31	was	be	AUX
admet-1317	177	32	determined	determine	VERB
admet-1317	177	33	by	by	ADP
admet-1317	177	34	evaluating	evaluate	VERB
admet-1317	177	35	their	their	PRON
admet-1317	177	36	resistance	resistance	NOUN
admet-1317	177	37	to	to	PART
admet-1317	177	38	compression	compression	VERB
admet-1317	177	39	when	when	SCONJ
admet-1317	177	40	an	an	DET
admet-1317	177	41	axial	axial	ADJ
admet-1317	177	42	force	force	NOUN
admet-1317	177	43	was	be	AUX
admet-1317	177	44	applied	apply	VERB
admet-1317	177	45	.	.	PUNCT
admet-1317	178	1	this	this	PRON
admet-1317	178	2	is	be	AUX
admet-1317	178	3	a	a	DET
admet-1317	178	4	commonly	commonly	ADV
admet-1317	178	5	used	use	VERB
admet-1317	178	6	method	method	NOUN
admet-1317	178	7	to	to	PART
admet-1317	178	8	evaluate	evaluate	VERB
admet-1317	178	9	the	the	DET
admet-1317	178	10	mechanical	mechanical	ADJ
admet-1317	178	11	properties	property	NOUN
admet-1317	178	12	of	of	ADP
admet-1317	178	13	mns	mns	PROPN
admet-1317	178	14	.	.	PUNCT
admet-1317	179	1	the	the	DET
admet-1317	179	2	applied	apply	VERB
admet-1317	179	3	axial	axial	ADJ
admet-1317	179	4	force	force	NOUN
admet-1317	179	5	was	be	AUX
admet-1317	179	6	32n	32n	NOUN
admet-1317	179	7	,	,	PUNCT
admet-1317	179	8	which	which	PRON
admet-1317	179	9	refers	refer	VERB
admet-1317	179	10	to	to	ADP
admet-1317	179	11	the	the	DET
admet-1317	179	12	maximum	maximum	ADJ
admet-1317	179	13	force	force	NOUN
admet-1317	179	14	applied	apply	VERB
admet-1317	179	15	by	by	ADP
admet-1317	179	16	a	a	DET
admet-1317	179	17	human	human	NOUN
admet-1317	179	18	during	during	ADP
admet-1317	179	19	the	the	DET
admet-1317	179	20	manual	manual	ADJ
admet-1317	179	21	insertion	insertion	NOUN
admet-1317	179	22	of	of	ADP
admet-1317	179	23	mns	mns	PROPN
admet-1317	179	24	[	[	X
admet-1317	179	25	18	18	NUM
admet-1317	179	26	]	]	PUNCT
admet-1317	179	27	.	.	PUNCT
admet-1317	180	1	the	the	DET
admet-1317	180	2	results	result	NOUN
admet-1317	180	3	revealed	reveal	VERB
admet-1317	180	4	a	a	DET
admet-1317	180	5	reduction	reduction	NOUN
admet-1317	180	6	in	in	ADP
admet-1317	180	7	post	post	ADJ
admet-1317	180	8	-	-	ADJ
admet-1317	180	9	compression	compression	ADJ
admet-1317	180	10	height	height	NOUN
admet-1317	180	11	,	,	PUNCT
admet-1317	180	12	bending	bend	VERB
admet-1317	180	13	in	in	ADP
admet-1317	180	14	certain	certain	ADJ
admet-1317	180	15	needles	needle	NOUN
admet-1317	180	16	,	,	PUNCT
admet-1317	180	17	and	and	CCONJ
admet-1317	180	18	needle	needle	NOUN
admet-1317	180	19	fracture	fracture	NOUN
admet-1317	180	20	in	in	ADP
admet-1317	180	21	some	some	DET
admet-1317	180	22	formulas	formula	NOUN
admet-1317	180	23	.	.	PUNCT
admet-1317	181	1	f1	f1	NOUN
admet-1317	181	2	and	and	CCONJ
admet-1317	181	3	f2	f2	PROPN
admet-1317	181	4	resulted	result	VERB
admet-1317	181	5	in	in	ADP
admet-1317	181	6	the	the	DET
admet-1317	181	7	formation	formation	NOUN
admet-1317	181	8	of	of	ADP
admet-1317	181	9	delicate	delicate	ADJ
admet-1317	181	10	mns	mn	NOUN
admet-1317	181	11	,	,	PUNCT
admet-1317	181	12	that	that	PRON
admet-1317	181	13	were	be	AUX
admet-1317	181	14	easily	easily	ADV
admet-1317	181	15	broken	break	VERB
admet-1317	181	16	when	when	SCONJ
admet-1317	181	17	moved	move	VERB
admet-1317	181	18	before	before	ADP
admet-1317	181	19	subjection	subjection	NOUN
admet-1317	181	20	to	to	PART
admet-1317	181	21	compression	compression	VERB
admet-1317	181	22	.	.	PUNCT
admet-1317	182	1	f3	f3	ADJ
admet-1317	182	2	-	-	PUNCT
admet-1317	182	3	f7	f7	PROPN
admet-1317	182	4	showed	show	VERB
admet-1317	182	5	needle	needle	NOUN
admet-1317	182	6	fracture	fracture	NOUN
admet-1317	182	7	upon	upon	SCONJ
admet-1317	182	8	exposure	exposure	NOUN
admet-1317	182	9	to	to	ADP
admet-1317	182	10	compression	compression	NOUN
admet-1317	182	11	.	.	PUNCT
admet-1317	183	1	f8	f8	PROPN
admet-1317	183	2	,	,	PUNCT
admet-1317	183	3	f9	f9	PROPN
admet-1317	183	4	,	,	PUNCT
admet-1317	183	5	f13	f13	NOUN
admet-1317	183	6	and	and	CCONJ
admet-1317	183	7	f11	f11	PROPN
admet-1317	183	8	revealed	reveal	VERB
admet-1317	183	9	mns	mns	PROPN
admet-1317	183	10	bending	bend	VERB
admet-1317	183	11	rather	rather	ADV
admet-1317	183	12	than	than	ADP
admet-1317	183	13	fracturing	fracture	VERB
admet-1317	183	14	.	.	PUNCT
admet-1317	184	1	this	this	PRON
admet-1317	184	2	refers	refer	VERB
admet-1317	184	3	to	to	ADP
admet-1317	184	4	their	their	PRON
admet-1317	184	5	ability	ability	NOUN
admet-1317	184	6	to	to	PART
admet-1317	184	7	withstand	withstand	VERB
admet-1317	184	8	the	the	DET
admet-1317	184	9	applied	apply	VERB
admet-1317	184	10	force	force	NOUN
admet-1317	184	11	better	well	ADJ
admet-1317	184	12	than	than	ADP
admet-1317	184	13	the	the	DET
admet-1317	184	14	rest	rest	NOUN
admet-1317	184	15	of	of	ADP
admet-1317	184	16	the	the	DET
admet-1317	184	17	formulas	formula	NOUN
admet-1317	184	18	.	.	PUNCT
admet-1317	185	1	a	a	DET
admet-1317	185	2	higher	high	ADJ
admet-1317	185	3	concentration	concentration	NOUN
admet-1317	185	4	of	of	ADP
admet-1317	185	5	ha	ha	INTJ
admet-1317	185	6	polymer	polymer	NOUN
admet-1317	185	7	has	have	AUX
admet-1317	185	8	resulted	result	VERB
admet-1317	185	9	in	in	ADP
admet-1317	185	10	a	a	DET
admet-1317	185	11	relatively	relatively	ADV
admet-1317	185	12	stronger	strong	ADJ
admet-1317	185	13	mn	mn	PROPN
admet-1317	185	14	array	array	NOUN
admet-1317	185	15	.	.	PUNCT
admet-1317	186	1	f11	f11	PROPN
admet-1317	186	2	was	be	AUX
admet-1317	186	3	the	the	DET
admet-1317	186	4	most	most	ADV
admet-1317	186	5	successful	successful	ADJ
admet-1317	186	6	formulation	formulation	NOUN
admet-1317	186	7	yielding	yield	VERB
admet-1317	186	8	completely	completely	ADV
admet-1317	186	9	formed	form	VERB
admet-1317	186	10	and	and	CCONJ
admet-1317	186	11	strong	strong	ADJ
admet-1317	186	12	mn	mn	PROPN
admet-1317	186	13	arrays	array	VERB
admet-1317	186	14	with	with	ADP
admet-1317	186	15	the	the	DET
admet-1317	186	16	lowest	low	ADJ
admet-1317	186	17	height	height	NOUN
admet-1317	186	18	reduction	reduction	NOUN
admet-1317	186	19	percentage	percentage	NOUN
admet-1317	186	20	.	.	PUNCT
admet-1317	187	1	the	the	DET
admet-1317	187	2	digital	digital	ADJ
admet-1317	187	3	microscope	microscope	NOUN
admet-1317	187	4	images	image	NOUN
admet-1317	187	5	of	of	ADP
admet-1317	187	6	mn	mn	PROPN
admet-1317	187	7	arrays	array	VERB
admet-1317	187	8	after	after	ADP
admet-1317	187	9	exposure	exposure	NOUN
admet-1317	187	10	to	to	ADP
admet-1317	187	11	compression	compression	NOUN
admet-1317	187	12	using	use	VERB
admet-1317	187	13	a	a	DET
admet-1317	187	14	texture	texture	ADJ
admet-1317	187	15	analyser	analyser	NOUN
admet-1317	187	16	instrument	instrument	NOUN
admet-1317	187	17	were	be	AUX
admet-1317	187	18	provided	provide	VERB
admet-1317	187	19	in	in	ADP
admet-1317	187	20	the	the	DET
admet-1317	187	21	supplementary	supplementary	ADJ
admet-1317	187	22	materials	material	NOUN
admet-1317	187	23	.	.	PUNCT
admet-1317	188	1	the	the	DET
admet-1317	188	2	degree	degree	NOUN
admet-1317	188	3	of	of	ADP
admet-1317	188	4	height	height	NOUN
admet-1317	188	5	reduction	reduction	NOUN
admet-1317	188	6	of	of	ADP
admet-1317	188	7	mns	mns	PROPN
admet-1317	188	8	for	for	ADP
admet-1317	188	9	different	different	ADJ
admet-1317	188	10	formulations	formulation	NOUN
admet-1317	188	11	was	be	AUX
admet-1317	188	12	varied	varied	ADJ
admet-1317	188	13	considerably	considerably	ADV
admet-1317	188	14	since	since	SCONJ
admet-1317	188	15	it	it	PRON
admet-1317	188	16	is	be	AUX
admet-1317	188	17	largely	largely	ADV
admet-1317	188	18	reliant	reliant	ADJ
admet-1317	188	19	on	on	ADP
admet-1317	188	20	its	its	PRON
admet-1317	188	21	unique	unique	ADJ
admet-1317	188	22	components	component	NOUN
admet-1317	188	23	.	.	PUNCT
admet-1317	189	1	the	the	DET
admet-1317	189	2	percentage	percentage	NOUN
admet-1317	189	3	of	of	ADP
admet-1317	189	4	height	height	NOUN
admet-1317	189	5	reduction	reduction	NOUN
admet-1317	189	6	after	after	ADP
admet-1317	189	7	compression	compression	NOUN
admet-1317	189	8	for	for	SCONJ
admet-1317	189	9	each	each	DET
admet-1317	189	10	mn	mn	PROPN
admet-1317	189	11	array	array	NOUN
admet-1317	189	12	formula	formula	NOUN
admet-1317	189	13	is	be	AUX
admet-1317	189	14	shown	show	VERB
admet-1317	189	15	in	in	ADP
admet-1317	189	16	table	table	NOUN
admet-1317	189	17	3	3	NUM
admet-1317	189	18	.	.	PUNCT
admet-1317	190	1	the	the	DET
admet-1317	190	2	percentage	percentage	NOUN
admet-1317	190	3	of	of	ADP
admet-1317	190	4	height	height	NOUN
admet-1317	190	5	reduction	reduction	NOUN
admet-1317	190	6	was	be	AUX
admet-1317	190	7	observed	observe	VERB
admet-1317	190	8	to	to	PART
admet-1317	190	9	be	be	AUX
admet-1317	190	10	inversely	inversely	ADV
admet-1317	190	11	proportional	proportional	ADJ
admet-1317	190	12	to	to	ADP
admet-1317	190	13	the	the	DET
admet-1317	190	14	concentration	concentration	NOUN
admet-1317	190	15	of	of	ADP
admet-1317	190	16	the	the	DET
admet-1317	190	17	ha	ha	INTJ
admet-1317	190	18	used	use	VERB
admet-1317	190	19	.	.	PUNCT
admet-1317	191	1	the	the	DET
admet-1317	191	2	mechanical	mechanical	ADJ
admet-1317	191	3	strength	strength	NOUN
admet-1317	191	4	increased	increase	VERB
admet-1317	191	5	by	by	ADP
admet-1317	191	6	adding	add	VERB
admet-1317	191	7	more	more	ADJ
admet-1317	191	8	polymer	polymer	NOUN
admet-1317	191	9	and	and	CCONJ
admet-1317	191	10	an	an	DET
admet-1317	191	11	enhancement	enhancement	NOUN
admet-1317	191	12	of	of	ADP
admet-1317	191	13	elasticity	elasticity	NOUN
admet-1317	191	14	was	be	AUX
admet-1317	191	15	achieved	achieve	VERB
admet-1317	191	16	by	by	ADP
admet-1317	191	17	further	further	ADJ
admet-1317	191	18	addition	addition	NOUN
admet-1317	191	19	of	of	ADP
admet-1317	191	20	tween	tween	NOUN
admet-1317	191	21	80	80	NUM
admet-1317	191	22	.	.	PUNCT
admet-1317	192	1	in	in	ADP
admet-1317	192	2	addition	addition	NOUN
admet-1317	192	3	to	to	ADP
admet-1317	192	4	the	the	DET
admet-1317	192	5	role	role	NOUN
admet-1317	192	6	of	of	ADP
admet-1317	192	7	tween	tween	NOUN
admet-1317	192	8	80	80	NUM
admet-1317	192	9	in	in	ADP
admet-1317	192	10	enhancing	enhance	VERB
admet-1317	192	11	the	the	DET
admet-1317	192	12	solubility	solubility	NOUN
admet-1317	192	13	of	of	ADP
admet-1317	192	14	lt-4	lt-4	NOUN
admet-1317	192	15	sodium	sodium	NOUN
admet-1317	192	16	,	,	PUNCT
admet-1317	192	17	plasticizers	plasticizer	NOUN
admet-1317	192	18	like	like	ADP
admet-1317	192	19	tween	tween	NOUN
admet-1317	192	20	80	80	NUM
admet-1317	192	21	are	be	AUX
admet-1317	192	22	also	also	ADV
admet-1317	192	23	commonly	commonly	ADV
admet-1317	192	24	used	use	VERB
admet-1317	192	25	to	to	PART
admet-1317	192	26	minimize	minimize	VERB
admet-1317	192	27	the	the	DET
admet-1317	192	28	intramolecular	intramolecular	ADJ
admet-1317	192	29	bonding	bonding	NOUN
admet-1317	192	30	between	between	ADP
admet-1317	192	31	polymer	polymer	NOUN
admet-1317	192	32	chains	chain	NOUN
admet-1317	192	33	.	.	PUNCT
admet-1317	193	1	this	this	PRON
admet-1317	193	2	provides	provide	VERB
admet-1317	193	3	the	the	DET
admet-1317	193	4	desired	desire	VERB
admet-1317	193	5	mechanical	mechanical	ADJ
admet-1317	193	6	film	film	NOUN
admet-1317	193	7	qualities	quality	NOUN
admet-1317	193	8	by	by	ADP
admet-1317	193	9	boosting	boost	VERB
admet-1317	193	10	flexibility	flexibility	NOUN
admet-1317	193	11	and	and	CCONJ
admet-1317	193	12	preventing	prevent	VERB
admet-1317	193	13	cracking	cracking	NOUN
admet-1317	193	14	,	,	PUNCT
admet-1317	193	15	which	which	PRON
admet-1317	193	16	is	be	AUX
admet-1317	193	17	frequently	frequently	ADV
admet-1317	193	18	employed	employ	VERB
admet-1317	193	19	in	in	ADP
admet-1317	193	20	the	the	DET
admet-1317	193	21	transdermal	transdermal	ADJ
admet-1317	193	22	drug	drug	NOUN
admet-1317	193	23	delivery	delivery	NOUN
admet-1317	193	24	field	field	NOUN
admet-1317	194	1	[	[	X
admet-1317	194	2	34	34	NUM
admet-1317	194	3	]	]	PUNCT
admet-1317	194	4	.	.	PUNCT
admet-1317	195	1	the	the	DET
admet-1317	195	2	viscosity	viscosity	NOUN
admet-1317	195	3	of	of	ADP
admet-1317	195	4	the	the	DET
admet-1317	195	5	polymeric	polymeric	ADJ
admet-1317	195	6	solution	solution	NOUN
admet-1317	195	7	is	be	AUX
admet-1317	195	8	proportional	proportional	ADJ
admet-1317	195	9	to	to	ADP
admet-1317	195	10	the	the	DET
admet-1317	195	11	amount	amount	NOUN
admet-1317	195	12	of	of	ADP
admet-1317	195	13	polymer	polymer	NOUN
admet-1317	195	14	utilized	utilize	VERB
admet-1317	195	15	.	.	PUNCT
admet-1317	196	1	the	the	PRON
admet-1317	196	2	higher	high	ADJ
admet-1317	196	3	the	the	DET
admet-1317	196	4	concentration	concentration	NOUN
admet-1317	196	5	of	of	ADP
admet-1317	196	6	polymer	polymer	NOUN
admet-1317	196	7	,	,	PUNCT
admet-1317	196	8	the	the	DET
admet-1317	196	9	more	more	ADV
admet-1317	196	10	viscous	viscous	ADJ
admet-1317	196	11	the	the	DET
admet-1317	196	12	polymeric	polymeric	ADJ
admet-1317	196	13	solution	solution	NOUN
admet-1317	196	14	is	be	AUX
admet-1317	196	15	leading	lead	VERB
admet-1317	196	16	to	to	ADP
admet-1317	196	17	the	the	DET
admet-1317	196	18	formation	formation	NOUN
admet-1317	196	19	of	of	ADP
admet-1317	196	20	stronger	strong	ADJ
admet-1317	196	21	mns	mn	NOUN
admet-1317	196	22	.	.	PUNCT
admet-1317	197	1	it	it	PRON
admet-1317	197	2	is	be	AUX
admet-1317	197	3	critical	critical	ADJ
admet-1317	197	4	to	to	PART
admet-1317	197	5	choose	choose	VERB
admet-1317	197	6	the	the	DET
admet-1317	197	7	right	right	ADJ
admet-1317	197	8	polymer	polymer	NOUN
admet-1317	197	9	concentration	concentration	NOUN
admet-1317	197	10	for	for	ADP
admet-1317	197	11	microneedle	microneedle	ADJ
admet-1317	197	12	shaft	shaft	NOUN
admet-1317	197	13	manufacturing	manufacturing	NOUN
admet-1317	197	14	;	;	PUNCT
admet-1317	197	15	the	the	DET
admet-1317	197	16	thickness	thickness	NOUN
admet-1317	197	17	of	of	ADP
admet-1317	197	18	the	the	DET
admet-1317	197	19	baseplate	baseplate	NOUN
admet-1317	197	20	that	that	PRON
admet-1317	197	21	supports	support	VERB
admet-1317	197	22	the	the	DET
admet-1317	197	23	microneedles	microneedle	NOUN
admet-1317	197	24	has	have	AUX
admet-1317	197	25	been	be	AUX
admet-1317	197	26	diminished	diminish	VERB
admet-1317	197	27	by	by	ADP
admet-1317	197	28	decreasing	decrease	VERB
admet-1317	197	29	the	the	DET
admet-1317	197	30	polymer	polymer	NOUN
admet-1317	197	31	content	content	NOUN
admet-1317	197	32	.	.	PUNCT
admet-1317	198	1	as	as	ADP
admet-1317	198	2	a	a	DET
admet-1317	198	3	result	result	NOUN
admet-1317	198	4	,	,	PUNCT
admet-1317	198	5	the	the	DET
admet-1317	198	6	needles	needle	NOUN
admet-1317	198	7	were	be	AUX
admet-1317	198	8	subjected	subject	VERB
admet-1317	198	9	to	to	ADP
admet-1317	198	10	an	an	DET
admet-1317	198	11	extra	extra	ADJ
admet-1317	198	12	-	-	ADJ
admet-1317	198	13	axial	axial	ADJ
admet-1317	198	14	applied	apply	VERB
admet-1317	198	15	force	force	NOUN
admet-1317	198	16	which	which	PRON
admet-1317	198	17	explains	explain	VERB
admet-1317	198	18	why	why	SCONJ
admet-1317	198	19	mechanical	mechanical	ADJ
admet-1317	198	20	strength	strength	NOUN
admet-1317	198	21	decreased	decrease	VERB
admet-1317	198	22	by	by	ADP
admet-1317	198	23	reducing	reduce	VERB
admet-1317	198	24	polymer	polymer	NOUN
admet-1317	198	25	concentration	concentration	NOUN
admet-1317	198	26	[	[	X
admet-1317	198	27	35	35	NUM
admet-1317	198	28	]	]	PUNCT
admet-1317	198	29	.	.	PUNCT
admet-1317	199	1	the	the	DET
admet-1317	199	2	mechanical	mechanical	ADJ
admet-1317	199	3	strength	strength	NOUN
admet-1317	199	4	evaluation	evaluation	NOUN
admet-1317	199	5	and	and	CCONJ
admet-1317	199	6	insertion	insertion	NOUN
admet-1317	199	7	study	study	NOUN
admet-1317	199	8	are	be	AUX
admet-1317	199	9	virtually	virtually	ADV
admet-1317	199	10	linked	link	VERB
admet-1317	199	11	.	.	PUNCT
admet-1317	200	1	since	since	SCONJ
admet-1317	200	2	they	they	PRON
admet-1317	200	3	are	be	AUX
admet-1317	200	4	related	relate	VERB
admet-1317	200	5	,	,	PUNCT
admet-1317	200	6	the	the	DET
admet-1317	200	7	crucial	crucial	ADJ
admet-1317	200	8	aspect	aspect	NOUN
admet-1317	200	9	of	of	ADP
admet-1317	200	10	efficient	efficient	ADJ
admet-1317	200	11	insertion	insertion	NOUN
admet-1317	200	12	is	be	AUX
admet-1317	200	13	based	base	VERB
admet-1317	200	14	on	on	ADP
admet-1317	200	15	the	the	DET
admet-1317	200	16	ability	ability	NOUN
admet-1317	200	17	of	of	ADP
admet-1317	200	18	the	the	DET
admet-1317	200	19	mns	mns	PROPN
admet-1317	200	20	to	to	PART
admet-1317	200	21	endure	endure	VERB
admet-1317	200	22	the	the	DET
admet-1317	200	23	applied	applied	ADJ
admet-1317	200	24	pressure	pressure	NOUN
admet-1317	200	25	[	[	X
admet-1317	200	26	36	36	NUM
admet-1317	200	27	]	]	PUNCT
admet-1317	200	28	.	.	PUNCT
admet-1317	201	1	the	the	DET
admet-1317	201	2	standard	standard	PROPN
admet-1317	201	3	mn	mn	PROPN
admet-1317	201	4	array	array	NOUN
admet-1317	201	5	height	height	NOUN
admet-1317	201	6	was	be	AUX
admet-1317	201	7	found	find	VERB
admet-1317	201	8	to	to	PART
admet-1317	201	9	be	be	AUX
admet-1317	201	10	432	432	NUM
admet-1317	201	11	±	±	NUM
admet-1317	201	12	6.4	6.4	NUM
admet-1317	201	13	µm	µm	NUM
admet-1317	202	1	and	and	CCONJ
admet-1317	202	2	it	it	PRON
admet-1317	202	3	was	be	AUX
admet-1317	202	4	used	use	VERB
admet-1317	202	5	for	for	ADP
admet-1317	202	6	the	the	DET
admet-1317	202	7	comparison	comparison	NOUN
admet-1317	202	8	of	of	ADP
admet-1317	202	9	height	height	NOUN
admet-1317	202	10	reduction	reduction	NOUN
admet-1317	202	11	with	with	ADP
admet-1317	202	12	other	other	ADJ
admet-1317	202	13	arrays	array	NOUN
admet-1317	202	14	subjected	subject	VERB
admet-1317	202	15	to	to	ADP
admet-1317	202	16	compression	compression	NOUN
admet-1317	202	17	.	.	PUNCT
admet-1317	203	1	in	in	ADP
admet-1317	203	2	vitro	vitro	X
admet-1317	203	3	drug	drug	NOUN
admet-1317	203	4	release	release	NOUN
admet-1317	203	5	study	study	NOUN
admet-1317	203	6	.	.	PUNCT
admet-1317	204	1	in	in	ADP
admet-1317	204	2	vitro	vitro	X
admet-1317	204	3	cumulative	cumulative	ADJ
admet-1317	204	4	drug	drug	NOUN
admet-1317	204	5	release	release	NOUN
admet-1317	204	6	percentages	percentage	NOUN
admet-1317	204	7	for	for	ADP
admet-1317	204	8	the	the	DET
admet-1317	204	9	chosen	choose	VERB
admet-1317	204	10	formulas	formula	NOUN
admet-1317	204	11	(	(	PUNCT
admet-1317	204	12	f8	f8	PROPN
admet-1317	204	13	,	,	PUNCT
admet-1317	204	14	f9	f9	PROPN
admet-1317	204	15	,	,	PUNCT
admet-1317	204	16	f10	f10	NOUN
admet-1317	204	17	and	and	CCONJ
admet-1317	204	18	f11	f11	NOUN
admet-1317	204	19	)	)	PUNCT
admet-1317	204	20	over	over	ADP
admet-1317	204	21	1	1	NUM
admet-1317	204	22	hour	hour	NOUN
admet-1317	204	23	are	be	AUX
admet-1317	204	24	illustrated	illustrate	VERB
admet-1317	204	25	in	in	ADP
admet-1317	204	26	figure	figure	NOUN
admet-1317	204	27	2	2	NUM
admet-1317	204	28	.	.	PUNCT
admet-1317	205	1	the	the	DET
admet-1317	205	2	graph	graph	NOUN
admet-1317	205	3	demonstrates	demonstrate	VERB
admet-1317	205	4	that	that	SCONJ
admet-1317	205	5	the	the	DET
admet-1317	205	6	release	release	NOUN
admet-1317	205	7	profile	profile	NOUN
admet-1317	205	8	from	from	ADP
admet-1317	205	9	the	the	DET
admet-1317	205	10	different	different	ADJ
admet-1317	205	11	formulations	formulation	NOUN
admet-1317	205	12	is	be	AUX
admet-1317	205	13	almost	almost	ADV
admet-1317	205	14	similar	similar	ADJ
admet-1317	205	15	,	,	PUNCT
admet-1317	205	16	with	with	ADP
admet-1317	205	17	a	a	DET
admet-1317	205	18	non	non	ADJ
admet-1317	205	19	-	-	ADJ
admet-1317	205	20	significant	significant	ADJ
admet-1317	205	21	difference	difference	NOUN
admet-1317	205	22	between	between	ADP
admet-1317	205	23	them	they	PRON
admet-1317	205	24	(	(	PUNCT
admet-1317	205	25	p	p	X
admet-1317	205	26	>	>	X
admet-1317	205	27	0.05	0.05	NUM
admet-1317	205	28	)	)	PUNCT
admet-1317	205	29	.	.	PUNCT
admet-1317	206	1	the	the	DET
admet-1317	206	2	release	release	NOUN
admet-1317	206	3	of	of	ADP
admet-1317	206	4	lt-4	lt-4	NOUN
admet-1317	206	5	sodium	sodium	NOUN
admet-1317	206	6	was	be	AUX
admet-1317	206	7	initiated	initiate	VERB
admet-1317	206	8	within	within	ADP
admet-1317	206	9	the	the	DET
admet-1317	206	10	first	first	ADJ
admet-1317	206	11	5	5	NUM
admet-1317	206	12	minutes	minute	NOUN
admet-1317	206	13	as	as	SCONJ
admet-1317	206	14	the	the	DET
admet-1317	206	15	mns	mn	NOUN
admet-1317	206	16	’	'	PUNCT
admet-1317	206	17	tips	tip	NOUN
admet-1317	206	18	became	become	VERB
admet-1317	206	19	hydrated	hydrated	ADJ
admet-1317	206	20	and	and	CCONJ
admet-1317	206	21	began	begin	VERB
admet-1317	206	22	to	to	PART
admet-1317	206	23	dissolve	dissolve	VERB
admet-1317	206	24	by	by	ADP
admet-1317	206	25	contact	contact	NOUN
admet-1317	206	26	with	with	ADP
admet-1317	206	27	water	water	NOUN
admet-1317	206	28	.	.	PUNCT
admet-1317	207	1	after	after	ADP
admet-1317	207	2	that	that	PRON
admet-1317	207	3	,	,	PUNCT
admet-1317	207	4	the	the	DET
admet-1317	207	5	dissolution	dissolution	NOUN
admet-1317	207	6	of	of	ADP
admet-1317	207	7	mns	mns	PROPN
admet-1317	207	8	increased	increase	VERB
admet-1317	207	9	with	with	ADP
admet-1317	207	10	a	a	DET
admet-1317	207	11	simultaneous	simultaneous	ADJ
admet-1317	207	12	increase	increase	NOUN
admet-1317	207	13	in	in	ADP
admet-1317	207	14	lt-4	lt-4	NOUN
admet-1317	207	15	sodium	sodium	NOUN
admet-1317	207	16	release	release	NOUN
admet-1317	207	17	over	over	ADP
admet-1317	207	18	an	an	DET
admet-1317	207	19	hour	hour	NOUN
admet-1317	207	20	.	.	PUNCT
admet-1317	208	1	during	during	ADP
admet-1317	208	2	this	this	DET
admet-1317	208	3	hour	hour	NOUN
admet-1317	208	4	,	,	PUNCT
admet-1317	208	5	the	the	DET
admet-1317	208	6	mn	mn	PROPN
admet-1317	208	7	arrays	array	VERB
admet-1317	208	8	were	be	AUX
admet-1317	208	9	diminished	diminish	VERB
admet-1317	208	10	gradually	gradually	ADV
admet-1317	208	11	until	until	SCONJ
admet-1317	208	12	they	they	PRON
admet-1317	208	13	eventually	eventually	ADV
admet-1317	208	14	vanished	vanish	VERB
admet-1317	208	15	after	after	ADP
admet-1317	208	16	one	one	NUM
admet-1317	208	17	hour	hour	NOUN
admet-1317	208	18	.	.	PUNCT
admet-1317	209	1	although	although	SCONJ
admet-1317	209	2	there	there	PRON
admet-1317	209	3	is	be	VERB
admet-1317	209	4	a	a	DET
admet-1317	209	5	non	non	ADJ
admet-1317	209	6	-	-	ADJ
admet-1317	209	7	significant	significant	ADJ
admet-1317	209	8	difference	difference	NOUN
admet-1317	209	9	in	in	ADP
admet-1317	209	10	the	the	DET
admet-1317	209	11	release	release	NOUN
admet-1317	209	12	profiles	profile	NOUN
admet-1317	209	13	between	between	ADP
admet-1317	209	14	different	different	ADJ
admet-1317	209	15	formulations	formulation	NOUN
admet-1317	209	16	,	,	PUNCT
admet-1317	209	17	it	it	PRON
admet-1317	209	18	can	can	AUX
admet-1317	209	19	be	be	AUX
admet-1317	209	20	observed	observe	VERB
admet-1317	209	21	that	that	SCONJ
admet-1317	209	22	the	the	DET
admet-1317	209	23	release	release	NOUN
admet-1317	209	24	of	of	ADP
admet-1317	209	25	lt-4	lt-4	NOUN
admet-1317	209	26	sodium	sodium	NOUN
admet-1317	209	27	from	from	ADP
admet-1317	209	28	f8	f8	PROPN
admet-1317	209	29	and	and	CCONJ
admet-1317	209	30	f9	f9	PROPN
admet-1317	209	31	was	be	AUX
admet-1317	209	32	relatively	relatively	ADV
admet-1317	209	33	higher	high	ADJ
admet-1317	209	34	than	than	ADP
admet-1317	209	35	f10	f10	NOUN
admet-1317	209	36	and	and	CCONJ
admet-1317	209	37	f11	f11	NOUN
admet-1317	209	38	.	.	PUNCT
admet-1317	210	1	this	this	PRON
admet-1317	210	2	may	may	AUX
admet-1317	210	3	be	be	AUX
admet-1317	210	4	due	due	ADJ
admet-1317	210	5	to	to	ADP
admet-1317	210	6	the	the	DET
admet-1317	210	7	presence	presence	NOUN
admet-1317	210	8	of	of	ADP
admet-1317	210	9	a	a	DET
admet-1317	210	10	higher	high	ADJ
admet-1317	210	11	ratio	ratio	NOUN
admet-1317	210	12	of	of	ADP
admet-1317	210	13	ha	ha	INTJ
admet-1317	210	14	in	in	ADP
admet-1317	210	15	f10	f10	NOUN
admet-1317	210	16	and	and	CCONJ
admet-1317	210	17	f11	f11	NOUN
admet-1317	210	18	.	.	PUNCT
admet-1317	211	1	after	after	ADP
admet-1317	211	2	1	1	NUM
admet-1317	211	3	hour	hour	NOUN
admet-1317	211	4	,	,	PUNCT
admet-1317	211	5	the	the	DET
admet-1317	211	6	release	release	NOUN
admet-1317	211	7	of	of	ADP
admet-1317	211	8	lt-4	lt-4	NOUN
admet-1317	211	9	sodium	sodium	NOUN
admet-1317	211	10	from	from	ADP
admet-1317	211	11	different	different	ADJ
admet-1317	211	12	mn	mn	PROPN
admet-1317	211	13	arrays	array	NOUN
admet-1317	211	14	has	have	AUX
admet-1317	211	15	reached	reach	VERB
admet-1317	211	16	96	96	NUM
admet-1317	211	17	-	-	SYM
admet-1317	211	18	98	98	NUM
admet-1317	211	19	%	%	NOUN
admet-1317	211	20	.	.	PUNCT
admet-1317	212	1	admet	admet	PROPN
admet-1317	212	2	&	&	CCONJ
admet-1317	212	3	dmpk	dmpk	PROPN
admet-1317	212	4	10(3	10(3	NUM
admet-1317	212	5	)	)	PUNCT
admet-1317	212	6	(	(	PUNCT
admet-1317	212	7	2022	2022	NUM
admet-1317	212	8	)	)	PUNCT
admet-1317	212	9	213	213	NUM
admet-1317	212	10	-	-	SYM
admet-1317	212	11	230	230	NUM
admet-1317	212	12	transdermal	transdermal	ADJ
admet-1317	212	13	delivery	delivery	NOUN
admet-1317	212	14	of	of	ADP
admet-1317	212	15	levothyroxine	levothyroxine	NOUN
admet-1317	212	16	via	via	ADP
admet-1317	212	17	dissolving	dissolve	VERB
admet-1317	212	18	microneedles	microneedle	NOUN
admet-1317	212	19	doi	doi	PROPN
admet-1317	212	20	:	:	PUNCT
admet-1317	212	21	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	VERB
admet-1317	212	22	221	221	NUM
admet-1317	212	23	table	table	NOUN
admet-1317	212	24	3	3	NUM
admet-1317	212	25	.	.	PUNCT
admet-1317	213	1	mean	mean	PROPN
admet-1317	213	2	height	height	NOUN
admet-1317	213	3	,	,	PUNCT
admet-1317	213	4	height	height	NOUN
admet-1317	213	5	percentage	percentage	NOUN
admet-1317	213	6	and	and	CCONJ
admet-1317	213	7	height	height	NOUN
admet-1317	213	8	reduction	reduction	NOUN
admet-1317	213	9	percentage	percentage	NOUN
admet-1317	213	10	after	after	ADP
admet-1317	213	11	compression	compression	NOUN
admet-1317	213	12	for	for	ADP
admet-1317	213	13	each	each	DET
admet-1317	213	14	mn	mn	PROPN
admet-1317	213	15	array	array	PROPN
admet-1317	213	16	formula	formula	NOUN
admet-1317	213	17	.	.	PUNCT
admet-1317	214	1	data	datum	NOUN
admet-1317	214	2	is	be	AUX
admet-1317	214	3	presented	present	VERB
admet-1317	214	4	as	as	ADP
admet-1317	214	5	the	the	DET
admet-1317	214	6	mean	mean	ADJ
admet-1317	214	7	±	±	PROPN
admet-1317	214	8	sd	sd	ADP
admet-1317	214	9	formula	formula	NOUN
admet-1317	214	10	code	code	NOUN
admet-1317	214	11	mean	mean	NOUN
admet-1317	214	12	height	height	NOUN
admet-1317	214	13	(	(	PUNCT
admet-1317	214	14	µm	µm	NOUN
admet-1317	214	15	)	)	PUNCT
admet-1317	214	16	after	after	ADP
admet-1317	214	17	compression	compression	NOUN
admet-1317	214	18	height	height	NOUN
admet-1317	214	19	%	%	NOUN
admet-1317	214	20	after	after	ADP
admet-1317	214	21	compression	compression	NOUN
admet-1317	214	22	height	height	NOUN
admet-1317	214	23	reduction	reduction	NOUN
admet-1317	214	24	%	%	NOUN
admet-1317	214	25	f3	f3	PROPN
admet-1317	214	26	277.65	277.65	NUM
admet-1317	214	27	±	±	NUM
admet-1317	214	28	4	4	NUM
admet-1317	214	29	67.80	67.80	NUM
admet-1317	214	30	±	±	NUM
admet-1317	214	31	4	4	NUM
admet-1317	214	32	32.24	32.24	NUM
admet-1317	214	33	±	±	NUM
admet-1317	214	34	2	2	NUM
admet-1317	214	35	f4	f4	PROPN
admet-1317	214	36	292.93	292.93	NUM
admet-1317	214	37	±	±	NUM
admet-1317	214	38	2	2	NUM
admet-1317	214	39	68.70	68.70	NUM
admet-1317	214	40	±	±	NUM
admet-1317	214	41	8	8	NUM
admet-1317	214	42	31.30	31.30	NUM
admet-1317	214	43	±	±	NUM
admet-1317	214	44	4	4	NUM
admet-1317	214	45	f5	f5	NOUN
admet-1317	214	46	326.17	326.17	NUM
admet-1317	214	47	±	±	NUM
admet-1317	214	48	5	5	NUM
admet-1317	214	49	75.50	75.50	NUM
admet-1317	214	50	±	±	NUM
admet-1317	214	51	4	4	NUM
admet-1317	214	52	24.51	24.51	NUM
admet-1317	214	53	±	±	NUM
admet-1317	214	54	6	6	NUM
admet-1317	214	55	f6	f6	PROPN
admet-1317	214	56	349.56	349.56	NUM
admet-1317	214	57	±	±	NUM
admet-1317	214	58	6	6	NUM
admet-1317	214	59	80.91	80.91	NUM
admet-1317	214	60	±	±	NUM
admet-1317	214	61	5	5	NUM
admet-1317	214	62	19.09	19.09	NUM
admet-1317	214	63	±	±	NUM
admet-1317	214	64	8	8	NUM
admet-1317	214	65	f7	f7	PROPN
admet-1317	214	66	367.44	367.44	NUM
admet-1317	214	67	±	±	NUM
admet-1317	214	68	4	4	NUM
admet-1317	214	69	85.05	85.05	NUM
admet-1317	214	70	±	±	NUM
admet-1317	214	71	4	4	NUM
admet-1317	214	72	14.95	14.95	NUM
admet-1317	214	73	±	±	NUM
admet-1317	214	74	3	3	NUM
admet-1317	214	75	f8	f8	PROPN
admet-1317	214	76	382.44	382.44	NUM
admet-1317	214	77	±	±	NUM
admet-1317	214	78	8	8	NUM
admet-1317	214	79	88.52	88.52	NUM
admet-1317	214	80	±	±	NUM
admet-1317	214	81	2	2	NUM
admet-1317	214	82	11.48	11.48	NUM
admet-1317	214	83	±	±	NUM
admet-1317	214	84	2	2	NUM
admet-1317	214	85	f9	f9	PROPN
admet-1317	214	86	399.72	399.72	NUM
admet-1317	214	87	±	±	NUM
admet-1317	214	88	7	7	NUM
admet-1317	214	89	92.52	92.52	NUM
admet-1317	214	90	±	±	NUM
admet-1317	214	91	3	3	NUM
admet-1317	214	92	7.48	7.48	NUM
admet-1317	214	93	±	±	NUM
admet-1317	214	94	5	5	NUM
admet-1317	214	95	f10	f10	NOUN
admet-1317	214	96	402.76	402.76	NUM
admet-1317	214	97	±	±	NUM
admet-1317	214	98	8	8	NUM
admet-1317	214	99	93.23	93.23	NUM
admet-1317	214	100	±	±	NUM
admet-1317	214	101	5	5	NUM
admet-1317	214	102	6.77	6.77	NUM
admet-1317	214	103	±	±	NUM
admet-1317	214	104	6	6	NUM
admet-1317	214	105	f11	f11	NOUN
admet-1317	214	106	411.22	411.22	NUM
admet-1317	214	107	±	±	NUM
admet-1317	214	108	4	4	NUM
admet-1317	214	109	95.18	95.18	NUM
admet-1317	214	110	±	±	NUM
admet-1317	214	111	2	2	NUM
admet-1317	214	112	4.82	4.82	NUM
admet-1317	214	113	±	±	NUM
admet-1317	214	114	4	4	NUM
admet-1317	214	115	the	the	DET
admet-1317	214	116	amount	amount	NOUN
admet-1317	214	117	of	of	ADP
admet-1317	214	118	the	the	DET
admet-1317	214	119	drug	drug	NOUN
admet-1317	214	120	released	release	VERB
admet-1317	214	121	from	from	ADP
admet-1317	214	122	the	the	DET
admet-1317	214	123	four	four	NUM
admet-1317	214	124	mn	mn	PROPN
admet-1317	214	125	arrays	array	NOUN
admet-1317	214	126	has	have	AUX
admet-1317	214	127	reached	reach	VERB
admet-1317	214	128	20	20	NUM
admet-1317	214	129	-	-	SYM
admet-1317	214	130	25	25	NUM
admet-1317	214	131	%	%	NOUN
admet-1317	214	132	five	five	NUM
admet-1317	214	133	minutes	minute	NOUN
admet-1317	214	134	following	follow	VERB
admet-1317	214	135	the	the	DET
admet-1317	214	136	start	start	NOUN
admet-1317	214	137	of	of	ADP
admet-1317	214	138	the	the	DET
admet-1317	214	139	test	test	NOUN
admet-1317	214	140	.	.	PUNCT
admet-1317	215	1	this	this	PRON
admet-1317	215	2	might	might	AUX
admet-1317	215	3	be	be	AUX
admet-1317	215	4	attributed	attribute	VERB
admet-1317	215	5	to	to	ADP
admet-1317	215	6	the	the	DET
admet-1317	215	7	drug	drug	NOUN
admet-1317	215	8	adsorption	adsorption	NOUN
admet-1317	215	9	on	on	ADP
admet-1317	215	10	the	the	DET
admet-1317	215	11	surface	surface	NOUN
admet-1317	215	12	of	of	ADP
admet-1317	215	13	the	the	DET
admet-1317	215	14	polymeric	polymeric	ADJ
admet-1317	215	15	mns	mn	NOUN
admet-1317	215	16	,	,	PUNCT
admet-1317	215	17	besides	besides	SCONJ
admet-1317	215	18	to	to	ADP
admet-1317	215	19	the	the	DET
admet-1317	215	20	hydrophilic	hydrophilic	ADJ
admet-1317	215	21	property	property	NOUN
admet-1317	215	22	of	of	ADP
admet-1317	215	23	ha	ha	INTJ
admet-1317	215	24	polymer	polymer	NOUN
admet-1317	215	25	that	that	PRON
admet-1317	215	26	will	will	AUX
admet-1317	215	27	quickly	quickly	ADV
admet-1317	215	28	dissolve	dissolve	VERB
admet-1317	215	29	in	in	ADP
admet-1317	215	30	water	water	NOUN
admet-1317	215	31	and	and	CCONJ
admet-1317	215	32	release	release	VERB
admet-1317	215	33	drugs	drug	NOUN
admet-1317	215	34	[	[	X
admet-1317	215	35	37	37	NUM
admet-1317	215	36	]	]	PUNCT
admet-1317	215	37	.	.	PUNCT
admet-1317	216	1	following	follow	VERB
admet-1317	216	2	the	the	DET
admet-1317	216	3	complete	complete	ADJ
admet-1317	216	4	dissolution	dissolution	NOUN
admet-1317	216	5	of	of	ADP
admet-1317	216	6	the	the	DET
admet-1317	216	7	needles	needle	NOUN
admet-1317	216	8	’	'	PUNCT
admet-1317	216	9	tip	tip	NOUN
admet-1317	216	10	within	within	ADP
admet-1317	216	11	5	5	NUM
admet-1317	216	12	minutes	minute	NOUN
admet-1317	216	13	,	,	PUNCT
admet-1317	216	14	a	a	DET
admet-1317	216	15	slower	slow	ADJ
admet-1317	216	16	rhythm	rhythm	NOUN
admet-1317	216	17	of	of	ADP
admet-1317	216	18	drug	drug	NOUN
admet-1317	216	19	release	release	NOUN
admet-1317	216	20	has	have	AUX
admet-1317	216	21	been	be	AUX
admet-1317	216	22	noticed	notice	VERB
admet-1317	216	23	.	.	PUNCT
admet-1317	217	1	this	this	PRON
admet-1317	217	2	is	be	AUX
admet-1317	217	3	because	because	SCONJ
admet-1317	217	4	the	the	DET
admet-1317	217	5	backing	backing	NOUN
admet-1317	217	6	layer	layer	NOUN
admet-1317	217	7	may	may	AUX
admet-1317	217	8	act	act	VERB
admet-1317	217	9	as	as	ADP
admet-1317	217	10	a	a	DET
admet-1317	217	11	reservoir	reservoir	NOUN
admet-1317	217	12	for	for	ADP
admet-1317	217	13	drug	drug	NOUN
admet-1317	217	14	release	release	NOUN
admet-1317	217	15	.	.	PUNCT
admet-1317	218	1	figure	figure	NOUN
admet-1317	218	2	2	2	NUM
admet-1317	218	3	.	.	PUNCT
admet-1317	218	4	lt-4	lt-4	NOUN
admet-1317	218	5	sodium	sodium	NOUN
admet-1317	218	6	release	release	NOUN
admet-1317	218	7	profile	profile	NOUN
admet-1317	218	8	from	from	ADP
admet-1317	218	9	f8	f8	PROPN
admet-1317	218	10	,	,	PUNCT
admet-1317	218	11	f9	f9	PROPN
admet-1317	218	12	,	,	PUNCT
admet-1317	218	13	f10	f10	NOUN
admet-1317	218	14	and	and	CCONJ
admet-1317	218	15	f11	f11	PROPN
admet-1317	218	16	mn	mn	PROPN
admet-1317	218	17	arrays	array	VERB
admet-1317	218	18	.	.	PUNCT
admet-1317	219	1	detection	detection	NOUN
admet-1317	219	2	of	of	ADP
admet-1317	219	3	microneedles	microneedle	NOUN
admet-1317	219	4	insertion	insertion	NOUN
admet-1317	219	5	ability	ability	NOUN
admet-1317	219	6	using	use	VERB
admet-1317	219	7	parafilm	parafilm	PROPN
admet-1317	219	8	m	m	PROPN
admet-1317	219	9	®	®	PROPN
admet-1317	219	10	.	.	PUNCT
admet-1317	220	1	eight	eight	NUM
admet-1317	220	2	layers	layer	NOUN
admet-1317	220	3	of	of	ADP
admet-1317	220	4	parafilm	parafilm	NOUN
admet-1317	220	5	m	m	PROPN
admet-1317	220	6	®	®	NOUN
admet-1317	220	7	were	be	AUX
admet-1317	220	8	employed	employ	VERB
admet-1317	220	9	to	to	PART
admet-1317	220	10	mimic	mimic	VERB
admet-1317	220	11	the	the	DET
admet-1317	220	12	skin	skin	NOUN
admet-1317	220	13	layers	layer	NOUN
admet-1317	220	14	in	in	ADP
admet-1317	220	15	order	order	NOUN
admet-1317	220	16	to	to	PART
admet-1317	220	17	assess	assess	VERB
admet-1317	220	18	the	the	DET
admet-1317	220	19	depth	depth	NOUN
admet-1317	220	20	of	of	ADP
admet-1317	220	21	penetration	penetration	NOUN
admet-1317	220	22	of	of	ADP
admet-1317	220	23	mns	mns	PROPN
admet-1317	220	24	in	in	ADP
admet-1317	220	25	the	the	DET
admet-1317	220	26	skin	skin	NOUN
admet-1317	220	27	.	.	PUNCT
admet-1317	221	1	as	as	SCONJ
admet-1317	221	2	reported	report	VERB
admet-1317	221	3	by	by	ADP
admet-1317	221	4	larrañeta	larrañeta	PROPN
admet-1317	221	5	et	et	PROPN
admet-1317	221	6	al	al	PROPN
admet-1317	221	7	.	.	PROPN
admet-1317	221	8	,	,	PUNCT
admet-1317	221	9	penetration	penetration	NOUN
admet-1317	221	10	is	be	AUX
admet-1317	221	11	regarded	regard	VERB
admet-1317	221	12	as	as	ADV
admet-1317	221	13	efficient	efficient	ADJ
admet-1317	221	14	if	if	SCONJ
admet-1317	221	15	greater	great	ADJ
admet-1317	221	16	than	than	ADP
admet-1317	221	17	20	20	NUM
admet-1317	221	18	%	%	NOUN
admet-1317	221	19	of	of	ADP
admet-1317	221	20	micro	micro	ADJ
admet-1317	221	21	conduits	conduit	NOUN
admet-1317	221	22	are	be	AUX
admet-1317	221	23	created	create	VERB
admet-1317	221	24	in	in	ADP
admet-1317	221	25	each	each	DET
admet-1317	221	26	layer	layer	NOUN
admet-1317	222	1	[	[	X
admet-1317	222	2	18	18	NUM
admet-1317	222	3	]	]	PUNCT
admet-1317	222	4	.	.	PUNCT
admet-1317	223	1	thus	thus	ADV
admet-1317	223	2	,	,	PUNCT
admet-1317	223	3	the	the	DET
admet-1317	223	4	insertion	insertion	NOUN
admet-1317	223	5	test	test	NOUN
admet-1317	223	6	findings	finding	NOUN
admet-1317	223	7	indicate	indicate	VERB
admet-1317	223	8	that	that	SCONJ
admet-1317	223	9	mns	mns	PROPN
admet-1317	223	10	are	be	AUX
admet-1317	223	11	located	locate	VERB
admet-1317	223	12	between	between	ADP
admet-1317	223	13	the	the	DET
admet-1317	223	14	third	third	ADJ
admet-1317	223	15	and	and	CCONJ
admet-1317	223	16	fourth	fourth	ADJ
admet-1317	223	17	layers	layer	NOUN
admet-1317	223	18	,	,	PUNCT
admet-1317	223	19	as	as	SCONJ
admet-1317	223	20	shown	show	VERB
admet-1317	223	21	in	in	ADP
admet-1317	223	22	figure	figure	NOUN
admet-1317	223	23	3	3	NUM
admet-1317	223	24	.	.	PUNCT
admet-1317	224	1	moreover	moreover	ADV
admet-1317	224	2	,	,	PUNCT
admet-1317	224	3	the	the	DET
admet-1317	224	4	thickness	thickness	NOUN
admet-1317	224	5	of	of	ADP
admet-1317	224	6	one	one	NUM
admet-1317	224	7	parafilm	parafilm	NOUN
admet-1317	224	8	m	m	PROPN
admet-1317	224	9	®	®	NOUN
admet-1317	224	10	layer	layer	NOUN
admet-1317	224	11	is	be	AUX
admet-1317	224	12	approximately	approximately	ADV
admet-1317	224	13	126	126	NUM
admet-1317	224	14	±	±	NUM
admet-1317	224	15	7	7	NUM
admet-1317	224	16	µm	µm	NOUN
admet-1317	224	17	,	,	PUNCT
admet-1317	224	18	implying	imply	VERB
admet-1317	224	19	that	that	SCONJ
admet-1317	224	20	the	the	DET
admet-1317	224	21	mns	mns	PROPN
admet-1317	224	22	were	be	AUX
admet-1317	224	23	penetrated	penetrate	VERB
admet-1317	224	24	up	up	ADP
admet-1317	224	25	to	to	ADP
admet-1317	224	26	378	378	NUM
admet-1317	224	27	µm	µm	ADP
admet-1317	224	28	depth	depth	NOUN
admet-1317	224	29	(	(	PUNCT
admet-1317	224	30	approximately	approximately	ADV
admet-1317	224	31	87	87	NUM
admet-1317	224	32	%	%	NOUN
admet-1317	224	33	of	of	ADP
admet-1317	224	34	needles	needle	NOUN
admet-1317	224	35	height	height	NOUN
admet-1317	224	36	)	)	PUNCT
admet-1317	224	37	.	.	PUNCT
admet-1317	225	1	as	as	SCONJ
admet-1317	225	2	demonstrated	demonstrate	VERB
admet-1317	225	3	in	in	ADP
admet-1317	225	4	figures	figure	NOUN
admet-1317	225	5	3	3	NUM
admet-1317	225	6	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	NUM
admet-1317	225	7	r.f	r.f	PROPN
admet-1317	225	8	.	.	PROPN
admet-1317	225	9	ghazi	ghazi	PROPN
admet-1317	225	10	and	and	CCONJ
admet-1317	225	11	m.h	m.h	PROPN
admet-1317	225	12	.	.	PROPN
admet-1317	225	13	al	al	PROPN
admet-1317	225	14	-	-	PUNCT
admet-1317	225	15	mayahy	mayahy	PROPN
admet-1317	225	16	admet	admet	PROPN
admet-1317	225	17	&	&	CCONJ
admet-1317	225	18	dmpk	dmpk	PROPN
admet-1317	225	19	10(3	10(3	NUM
admet-1317	225	20	)	)	PUNCT
admet-1317	225	21	(	(	PUNCT
admet-1317	225	22	2022	2022	NUM
admet-1317	225	23	)	)	PUNCT
admet-1317	225	24	213	213	NUM
admet-1317	225	25	-	-	SYM
admet-1317	225	26	230	230	NUM
admet-1317	225	27	222	222	NUM
admet-1317	225	28	and	and	CCONJ
admet-1317	225	29	4	4	NUM
admet-1317	225	30	,	,	PUNCT
admet-1317	225	31	f11	f11	PROPN
admet-1317	225	32	mn	mn	PROPN
admet-1317	225	33	arrays	array	NOUN
admet-1317	225	34	showed	show	VERB
admet-1317	225	35	100	100	NUM
admet-1317	225	36	%	%	NOUN
admet-1317	225	37	penetration	penetration	NOUN
admet-1317	225	38	in	in	ADP
admet-1317	225	39	the	the	DET
admet-1317	225	40	first	first	ADJ
admet-1317	225	41	and	and	CCONJ
admet-1317	225	42	second	second	ADJ
admet-1317	225	43	layers	layer	NOUN
admet-1317	225	44	and	and	CCONJ
admet-1317	225	45	50	50	NUM
admet-1317	225	46	%	%	NOUN
admet-1317	225	47	in	in	ADP
admet-1317	225	48	the	the	DET
admet-1317	225	49	third	third	ADJ
admet-1317	225	50	layer	layer	NOUN
admet-1317	225	51	.	.	PUNCT
admet-1317	226	1	this	this	PRON
admet-1317	226	2	indicates	indicate	VERB
admet-1317	226	3	their	their	PRON
admet-1317	226	4	adequate	adequate	ADJ
admet-1317	226	5	mechanical	mechanical	ADJ
admet-1317	226	6	strength	strength	NOUN
admet-1317	226	7	with	with	ADP
admet-1317	226	8	the	the	DET
admet-1317	226	9	sharpness	sharpness	NOUN
admet-1317	226	10	of	of	ADP
admet-1317	226	11	the	the	DET
admet-1317	226	12	tips	tip	NOUN
admet-1317	226	13	required	require	VERB
admet-1317	226	14	for	for	ADP
admet-1317	226	15	efficient	efficient	ADJ
admet-1317	226	16	penetration	penetration	NOUN
admet-1317	226	17	across	across	ADP
admet-1317	226	18	the	the	DET
admet-1317	226	19	skin	skin	NOUN
admet-1317	226	20	tissue	tissue	NOUN
admet-1317	226	21	barrier	barrier	NOUN
admet-1317	226	22	.	.	PUNCT
admet-1317	227	1	f8	f8	PROPN
admet-1317	227	2	,	,	PUNCT
admet-1317	227	3	f9	f9	PROPN
admet-1317	227	4	and	and	CCONJ
admet-1317	227	5	f10	f10	NOUN
admet-1317	227	6	have	have	AUX
admet-1317	227	7	exhibited	exhibit	VERB
admet-1317	227	8	a	a	DET
admet-1317	227	9	lower	low	ADJ
admet-1317	227	10	number	number	NOUN
admet-1317	227	11	of	of	ADP
admet-1317	227	12	micro	micro	ADJ
admet-1317	227	13	holes	hole	NOUN
admet-1317	227	14	,	,	PUNCT
admet-1317	227	15	especially	especially	ADV
admet-1317	227	16	in	in	ADP
admet-1317	227	17	the	the	DET
admet-1317	227	18	third	third	ADJ
admet-1317	227	19	layer	layer	NOUN
admet-1317	227	20	as	as	SCONJ
admet-1317	227	21	illustrated	illustrate	VERB
admet-1317	227	22	in	in	ADP
admet-1317	227	23	figure	figure	NOUN
admet-1317	227	24	4	4	NUM
admet-1317	227	25	,	,	PUNCT
admet-1317	227	26	proposing	propose	VERB
admet-1317	227	27	lower	low	ADJ
admet-1317	227	28	mechanical	mechanical	ADJ
admet-1317	227	29	properties	property	NOUN
admet-1317	227	30	probably	probably	ADV
admet-1317	227	31	due	due	ADJ
admet-1317	227	32	to	to	ADP
admet-1317	227	33	the	the	DET
admet-1317	227	34	lower	low	ADJ
admet-1317	227	35	concentration	concentration	NOUN
admet-1317	227	36	of	of	ADP
admet-1317	227	37	ha	ha	INTJ
admet-1317	227	38	polymer	polymer	NOUN
admet-1317	227	39	contained	contain	VERB
admet-1317	227	40	in	in	ADP
admet-1317	227	41	their	their	PRON
admet-1317	227	42	mn	mn	NOUN
admet-1317	227	43	arrays	array	VERB
admet-1317	227	44	.	.	PUNCT
admet-1317	228	1	figure	figure	VERB
admet-1317	228	2	3	3	NUM
admet-1317	228	3	.	.	X
admet-1317	228	4	insertion	insertion	NOUN
admet-1317	228	5	test	test	NOUN
admet-1317	228	6	using	use	VERB
admet-1317	228	7	parafilm	parafilm	PROPN
admet-1317	228	8	m	m	PROPN
admet-1317	228	9	®	®	NOUN
admet-1317	228	10	layers	layer	NOUN
admet-1317	228	11	by	by	ADP
admet-1317	228	12	f11	f11	PROPN
admet-1317	228	13	mn	mn	PROPN
admet-1317	228	14	array	array	NOUN
admet-1317	228	15	that	that	PRON
admet-1317	228	16	clearly	clearly	ADV
admet-1317	228	17	shows	show	VERB
admet-1317	228	18	the	the	DET
admet-1317	228	19	successful	successful	ADJ
admet-1317	228	20	penetration	penetration	NOUN
admet-1317	228	21	through	through	ADP
admet-1317	228	22	the	the	DET
admet-1317	228	23	3rd	3rd	ADJ
admet-1317	228	24	layer	layer	NOUN
admet-1317	228	25	.	.	PUNCT
admet-1317	229	1	figure	figure	VERB
admet-1317	229	2	4	4	NUM
admet-1317	229	3	.	.	PUNCT
admet-1317	230	1	illustration	illustration	NOUN
admet-1317	230	2	of	of	ADP
admet-1317	230	3	the	the	DET
admet-1317	230	4	insertion	insertion	NOUN
admet-1317	230	5	ratio	ratio	NOUN
admet-1317	230	6	of	of	ADP
admet-1317	230	7	the	the	DET
admet-1317	230	8	mn	mn	PROPN
admet-1317	230	9	arrays	array	VERB
admet-1317	230	10	(	(	PUNCT
admet-1317	230	11	f8	f8	PROPN
admet-1317	230	12	,	,	PUNCT
admet-1317	230	13	f9	f9	PROPN
admet-1317	230	14	,	,	PUNCT
admet-1317	230	15	f10	f10	NOUN
admet-1317	230	16	and	and	CCONJ
admet-1317	230	17	f11	f11	NOUN
admet-1317	230	18	)	)	PUNCT
admet-1317	230	19	created	create	VERB
admet-1317	230	20	in	in	ADP
admet-1317	230	21	parafilm	parafilm	NOUN
admet-1317	230	22	m	m	PROPN
admet-1317	230	23	®	®	NOUN
admet-1317	230	24	sheets	sheet	NOUN
admet-1317	230	25	.	.	PUNCT
admet-1317	231	1	insertion	insertion	NOUN
admet-1317	231	2	of	of	ADP
admet-1317	231	3	microneedle	microneedle	NOUN
admet-1317	231	4	arrays	array	VERB
admet-1317	231	5	into	into	ADP
admet-1317	231	6	excised	excise	VERB
admet-1317	231	7	human	human	ADJ
admet-1317	231	8	skin	skin	NOUN
admet-1317	231	9	.	.	PUNCT
admet-1317	232	1	to	to	PART
admet-1317	232	2	assess	assess	VERB
admet-1317	232	3	the	the	DET
admet-1317	232	4	mns	mn	NOUN
admet-1317	232	5	’	'	PUNCT
admet-1317	232	6	effectiveness	effectiveness	NOUN
admet-1317	232	7	in	in	ADP
admet-1317	232	8	the	the	DET
admet-1317	232	9	penetration	penetration	NOUN
admet-1317	232	10	of	of	ADP
admet-1317	232	11	the	the	DET
admet-1317	232	12	uppermost	uppermost	ADJ
admet-1317	232	13	layer	layer	NOUN
admet-1317	232	14	of	of	ADP
admet-1317	232	15	the	the	DET
admet-1317	232	16	skin	skin	NOUN
admet-1317	232	17	(	(	PUNCT
admet-1317	232	18	stratum	stratum	PROPN
admet-1317	232	19	corneum	corneum	PROPN
admet-1317	232	20	)	)	PUNCT
admet-1317	232	21	,	,	PUNCT
admet-1317	232	22	an	an	DET
admet-1317	232	23	insertion	insertion	NOUN
admet-1317	232	24	study	study	NOUN
admet-1317	232	25	using	use	VERB
admet-1317	232	26	human	human	ADJ
admet-1317	232	27	skin	skin	NOUN
admet-1317	232	28	was	be	AUX
admet-1317	232	29	performed	perform	VERB
admet-1317	232	30	.	.	PUNCT
admet-1317	233	1	figure	figure	NOUN
admet-1317	233	2	5	5	NUM
admet-1317	233	3	shows	show	VERB
admet-1317	233	4	the	the	DET
admet-1317	233	5	human	human	ADJ
admet-1317	233	6	skin	skin	NOUN
admet-1317	233	7	stained	stain	VERB
admet-1317	233	8	with	with	ADP
admet-1317	233	9	methylene	methylene	ADJ
admet-1317	233	10	blue	blue	ADJ
admet-1317	233	11	dye	dye	NOUN
admet-1317	233	12	after	after	ADP
admet-1317	233	13	treatment	treatment	NOUN
admet-1317	233	14	with	with	ADP
admet-1317	233	15	ha	ha	INTJ
admet-1317	233	16	mn	mn	PROPN
admet-1317	233	17	arrays	array	VERB
admet-1317	233	18	.	.	PUNCT
admet-1317	234	1	the	the	DET
admet-1317	234	2	pores	pore	NOUN
admet-1317	234	3	created	create	VERB
admet-1317	234	4	by	by	ADP
admet-1317	234	5	the	the	DET
admet-1317	234	6	mns	mns	PROPN
admet-1317	234	7	were	be	AUX
admet-1317	234	8	stained	stain	VERB
admet-1317	234	9	with	with	ADP
admet-1317	234	10	the	the	DET
admet-1317	234	11	dye	dye	NOUN
admet-1317	234	12	,	,	PUNCT
admet-1317	234	13	whereas	whereas	SCONJ
admet-1317	234	14	the	the	DET
admet-1317	234	15	intact	intact	ADJ
admet-1317	234	16	skin	skin	NOUN
admet-1317	234	17	remained	remain	VERB
admet-1317	234	18	unstained	unstaine	VERB
admet-1317	234	19	.	.	PUNCT
admet-1317	235	1	the	the	DET
admet-1317	235	2	10	10	NUM
admet-1317	235	3	×	×	PROPN
admet-1317	235	4	10	10	NUM
admet-1317	235	5	mn	mn	PROPN
admet-1317	235	6	arrays	array	VERB
admet-1317	235	7	with	with	ADP
admet-1317	235	8	varying	vary	VERB
admet-1317	235	9	concentrations	concentration	NOUN
admet-1317	235	10	of	of	ADP
admet-1317	235	11	ha	ha	INTJ
admet-1317	235	12	(	(	PUNCT
admet-1317	235	13	f8	f8	PROPN
admet-1317	235	14	,	,	PUNCT
admet-1317	235	15	f9	f9	PROPN
admet-1317	235	16	,	,	PUNCT
admet-1317	235	17	f10	f10	NOUN
admet-1317	235	18	and	and	CCONJ
admet-1317	235	19	f11	f11	PROPN
admet-1317	235	20	)	)	PUNCT
admet-1317	235	21	resulted	result	VERB
admet-1317	235	22	in	in	ADP
admet-1317	235	23	a	a	DET
admet-1317	235	24	75	75	NUM
admet-1317	235	25	to	to	PART
admet-1317	235	26	100	100	NUM
admet-1317	235	27	%	%	NOUN
admet-1317	235	28	insertion	insertion	NOUN
admet-1317	235	29	ratio	ratio	NOUN
admet-1317	235	30	after	after	SCONJ
admet-1317	235	31	1	1	NUM
admet-1317	235	32	minute	minute	NOUN
admet-1317	235	33	of	of	ADP
admet-1317	235	34	application	application	NOUN
admet-1317	235	35	of	of	ADP
admet-1317	235	36	mn	mn	PROPN
admet-1317	235	37	arrays	array	VERB
admet-1317	235	38	.	.	PUNCT
admet-1317	236	1	these	these	DET
admet-1317	236	2	findings	finding	NOUN
admet-1317	236	3	highlight	highlight	VERB
admet-1317	236	4	the	the	DET
admet-1317	236	5	capability	capability	NOUN
admet-1317	236	6	of	of	ADP
admet-1317	236	7	the	the	DET
admet-1317	236	8	mn	mn	PROPN
admet-1317	236	9	arrays	array	VERB
admet-1317	236	10	to	to	PART
admet-1317	236	11	penetrate	penetrate	VERB
admet-1317	236	12	the	the	DET
admet-1317	236	13	skin	skin	NOUN
admet-1317	236	14	effectively	effectively	ADV
admet-1317	236	15	[	[	X
admet-1317	236	16	32	32	NUM
admet-1317	236	17	]	]	PUNCT
admet-1317	236	18	.	.	PUNCT
admet-1317	237	1	the	the	DET
admet-1317	237	2	insertion	insertion	NOUN
admet-1317	237	3	ratio	ratio	NOUN
admet-1317	237	4	for	for	ADP
admet-1317	237	5	each	each	DET
admet-1317	237	6	sample	sample	NOUN
admet-1317	237	7	was	be	AUX
admet-1317	237	8	estimated	estimate	VERB
admet-1317	237	9	by	by	ADP
admet-1317	237	10	dividing	divide	VERB
admet-1317	237	11	the	the	DET
admet-1317	237	12	number	number	NOUN
admet-1317	237	13	of	of	ADP
admet-1317	237	14	blue	blue	ADJ
admet-1317	237	15	spots	spot	NOUN
admet-1317	237	16	on	on	ADP
admet-1317	237	17	the	the	DET
admet-1317	237	18	skin	skin	NOUN
admet-1317	237	19	after	after	ADP
admet-1317	237	20	insertion	insertion	NOUN
admet-1317	237	21	by	by	ADP
admet-1317	237	22	the	the	DET
admet-1317	237	23	number	number	NOUN
admet-1317	237	24	of	of	ADP
admet-1317	237	25	needles	needle	NOUN
admet-1317	237	26	in	in	ADP
admet-1317	237	27	the	the	DET
admet-1317	237	28	arrays	array	NOUN
admet-1317	237	29	[	[	X
admet-1317	237	30	16	16	NUM
admet-1317	237	31	]	]	PUNCT
admet-1317	237	32	.	.	PUNCT
admet-1317	238	1	the	the	DET
admet-1317	238	2	insertion	insertion	NOUN
admet-1317	238	3	ratio	ratio	NOUN
admet-1317	238	4	of	of	ADP
admet-1317	238	5	mn	mn	PROPN
admet-1317	238	6	arrays	array	NOUN
admet-1317	238	7	was	be	AUX
admet-1317	238	8	increased	increase	VERB
admet-1317	238	9	with	with	ADP
admet-1317	238	10	an	an	DET
admet-1317	238	11	increase	increase	NOUN
admet-1317	238	12	in	in	ADP
admet-1317	238	13	their	their	PRON
admet-1317	238	14	ha	ha	INTJ
admet-1317	238	15	content	content	NOUN
admet-1317	238	16	.	.	PUNCT
admet-1317	239	1	this	this	PRON
admet-1317	239	2	can	can	AUX
admet-1317	239	3	be	be	AUX
admet-1317	239	4	related	relate	VERB
admet-1317	239	5	to	to	ADP
admet-1317	239	6	the	the	DET
admet-1317	239	7	higher	high	ADJ
admet-1317	239	8	mechanical	mechanical	ADJ
admet-1317	239	9	strength	strength	NOUN
admet-1317	239	10	achieved	achieve	VERB
admet-1317	239	11	by	by	ADP
admet-1317	239	12	increasing	increase	VERB
admet-1317	239	13	the	the	DET
admet-1317	239	14	concentration	concentration	NOUN
admet-1317	239	15	of	of	ADP
admet-1317	239	16	ha	ha	INTJ
admet-1317	239	17	in	in	ADP
admet-1317	239	18	each	each	DET
admet-1317	239	19	formula	formula	NOUN
admet-1317	239	20	.	.	PUNCT
admet-1317	240	1	consequently	consequently	ADV
admet-1317	240	2	,	,	PUNCT
admet-1317	240	3	mn	mn	PROPN
admet-1317	240	4	formula	formula	NOUN
admet-1317	240	5	f11	f11	PROPN
admet-1317	240	6	demonstrated	demonstrate	VERB
admet-1317	240	7	a	a	DET
admet-1317	240	8	100	100	NUM
admet-1317	240	9	%	%	NOUN
admet-1317	240	10	insertion	insertion	NOUN
admet-1317	240	11	ratio	ratio	NOUN
admet-1317	240	12	due	due	ADP
admet-1317	240	13	to	to	ADP
admet-1317	240	14	their	their	PRON
admet-1317	240	15	higher	high	ADJ
admet-1317	240	16	ha	ha	INTJ
admet-1317	240	17	concentration	concentration	NOUN
admet-1317	240	18	(	(	PUNCT
admet-1317	240	19	50	50	NUM
admet-1317	240	20	%	%	NOUN
admet-1317	240	21	w	w	PROPN
admet-1317	240	22	/	/	SYM
admet-1317	240	23	v	v	NOUN
admet-1317	240	24	)	)	PUNCT
admet-1317	240	25	,	,	PUNCT
admet-1317	240	26	resulting	result	VERB
admet-1317	240	27	in	in	ADP
admet-1317	240	28	the	the	DET
admet-1317	240	29	greatest	great	ADJ
admet-1317	240	30	mechanical	mechanical	ADJ
admet-1317	240	31	strength	strength	NOUN
admet-1317	240	32	required	require	VERB
admet-1317	240	33	for	for	ADP
admet-1317	240	34	efficient	efficient	ADJ
admet-1317	240	35	skin	skin	NOUN
admet-1317	240	36	penetration	penetration	NOUN
admet-1317	240	37	.	.	PUNCT
admet-1317	241	1	mn	mn	PROPN
admet-1317	241	2	arrays	array	VERB
admet-1317	241	3	were	be	AUX
admet-1317	241	4	inserted	insert	VERB
admet-1317	241	5	into	into	ADP
admet-1317	241	6	the	the	DET
admet-1317	241	7	skin	skin	NOUN
admet-1317	241	8	using	use	VERB
admet-1317	241	9	gentle	gentle	ADJ
admet-1317	241	10	thumb	thumb	NOUN
admet-1317	241	11	pressure	pressure	NOUN
admet-1317	241	12	.	.	PUNCT
admet-1317	242	1	different	different	ADJ
admet-1317	242	2	types	type	NOUN
admet-1317	242	3	of	of	ADP
admet-1317	242	4	applicators	applicator	NOUN
admet-1317	242	5	have	have	AUX
admet-1317	242	6	been	be	AUX
admet-1317	242	7	designed	design	VERB
admet-1317	242	8	to	to	PART
admet-1317	242	9	minimize	minimize	VERB
admet-1317	242	10	variation	variation	NOUN
admet-1317	242	11	in	in	ADP
admet-1317	242	12	insertion	insertion	NOUN
admet-1317	242	13	forces	force	NOUN
admet-1317	242	14	for	for	ADP
admet-1317	242	15	the	the	DET
admet-1317	242	16	same	same	ADJ
admet-1317	242	17	mn	mn	PROPN
admet-1317	242	18	array	array	VERB
admet-1317	243	1	[	[	X
admet-1317	243	2	38,39	38,39	NOUN
admet-1317	243	3	]	]	X
admet-1317	243	4	.	.	PUNCT
admet-1317	244	1	when	when	SCONJ
admet-1317	244	2	appropriately	appropriately	ADV
admet-1317	244	3	engineered	engineer	VERB
admet-1317	244	4	,	,	PUNCT
admet-1317	244	5	the	the	DET
admet-1317	244	6	consistency	consistency	NOUN
admet-1317	244	7	of	of	ADP
admet-1317	244	8	the	the	DET
admet-1317	244	9	applied	apply	VERB
admet-1317	244	10	force	force	NOUN
admet-1317	244	11	can	can	AUX
admet-1317	244	12	be	be	AUX
admet-1317	244	13	better	well	ADJ
admet-1317	244	14	with	with	ADP
admet-1317	244	15	an	an	DET
admet-1317	244	16	applicator	applicator	NOUN
admet-1317	244	17	than	than	ADP
admet-1317	244	18	with	with	ADP
admet-1317	244	19	a	a	DET
admet-1317	244	20	thumb	thumb	NOUN
admet-1317	244	21	.	.	PUNCT
admet-1317	245	1	yet	yet	ADV
admet-1317	245	2	,	,	PUNCT
admet-1317	245	3	inserting	insert	VERB
admet-1317	245	4	mns	mns	PROPN
admet-1317	245	5	into	into	ADP
admet-1317	245	6	skin	skin	NOUN
admet-1317	245	7	using	use	VERB
admet-1317	245	8	a	a	DET
admet-1317	245	9	thumb	thumb	NOUN
admet-1317	245	10	force	force	NOUN
admet-1317	245	11	has	have	AUX
admet-1317	245	12	been	be	AUX
admet-1317	245	13	a	a	DET
admet-1317	245	14	typical	typical	ADJ
admet-1317	245	15	technique	technique	NOUN
admet-1317	245	16	of	of	ADP
admet-1317	245	17	administration	administration	NOUN
admet-1317	245	18	and	and	CCONJ
admet-1317	245	19	multiple	multiple	ADJ
admet-1317	245	20	groups	group	NOUN
admet-1317	245	21	have	have	AUX
admet-1317	245	22	clearly	clearly	ADV
admet-1317	245	23	confirmed	confirm	VERB
admet-1317	245	24	uniform	uniform	NOUN
admet-1317	245	25	and	and	CCONJ
admet-1317	245	26	full	full	ADJ
admet-1317	245	27	mn	mn	PROPN
admet-1317	245	28	array	array	NOUN
admet-1317	245	29	insertion	insertion	NOUN
admet-1317	245	30	while	while	SCONJ
admet-1317	245	31	using	use	VERB
admet-1317	245	32	this	this	DET
admet-1317	245	33	approach	approach	NOUN
admet-1317	245	34	[	[	X
admet-1317	245	35	40	40	NUM
admet-1317	245	36	-	-	SYM
admet-1317	245	37	42	42	NUM
admet-1317	245	38	]	]	PUNCT
admet-1317	245	39	.	.	PUNCT
admet-1317	246	1	0	0	NUM
admet-1317	247	1	50	50	NUM
admet-1317	247	2	100	100	NUM
admet-1317	247	3	150	150	NUM
admet-1317	247	4	layer	layer	NOUN
admet-1317	247	5	1	1	NUM
admet-1317	247	6	layer	layer	NOUN
admet-1317	247	7	2	2	NUM
admet-1317	247	8	layer	layer	NOUN
admet-1317	247	9	3	3	NUM
admet-1317	247	10	in	in	ADP
admet-1317	247	11	se	se	PROPN
admet-1317	247	12	rt	rt	PROPN
admet-1317	247	13	io	io	PROPN
admet-1317	247	14	n	n	PRON
admet-1317	247	15	r	r	NOUN
admet-1317	247	16	at	at	ADP
admet-1317	247	17	io	io	X
admet-1317	247	18	%	%	NOUN
admet-1317	247	19	f8	f8	PROPN
admet-1317	247	20	f9	f9	PROPN
admet-1317	247	21	f10	f10	PROPN
admet-1317	247	22	f11	f11	PROPN
admet-1317	247	23	admet	admet	PROPN
admet-1317	247	24	&	&	CCONJ
admet-1317	247	25	dmpk	dmpk	PROPN
admet-1317	247	26	10(3	10(3	NUM
admet-1317	247	27	)	)	PUNCT
admet-1317	247	28	(	(	PUNCT
admet-1317	247	29	2022	2022	NUM
admet-1317	247	30	)	)	PUNCT
admet-1317	247	31	213	213	NUM
admet-1317	247	32	-	-	SYM
admet-1317	247	33	230	230	NUM
admet-1317	247	34	transdermal	transdermal	ADJ
admet-1317	247	35	delivery	delivery	NOUN
admet-1317	247	36	of	of	ADP
admet-1317	247	37	levothyroxine	levothyroxine	NOUN
admet-1317	247	38	via	via	ADP
admet-1317	247	39	dissolving	dissolve	VERB
admet-1317	247	40	microneedles	microneedle	NOUN
admet-1317	247	41	doi	doi	PROPN
admet-1317	247	42	:	:	PUNCT
admet-1317	247	43	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	NUM
admet-1317	247	44	223	223	NUM
admet-1317	247	45	figure	figure	NOUN
admet-1317	247	46	5	5	NUM
admet-1317	247	47	.	.	PUNCT
admet-1317	248	1	digital	digital	ADJ
admet-1317	248	2	microscope	microscope	NOUN
admet-1317	248	3	images	image	NOUN
admet-1317	248	4	of	of	ADP
admet-1317	248	5	human	human	ADJ
admet-1317	248	6	skin	skin	NOUN
admet-1317	248	7	following	follow	VERB
admet-1317	248	8	the	the	DET
admet-1317	248	9	application	application	NOUN
admet-1317	248	10	of	of	ADP
admet-1317	248	11	ha	ha	INTJ
admet-1317	248	12	mn	mn	PROPN
admet-1317	248	13	arrays	array	VERB
admet-1317	248	14	and	and	CCONJ
admet-1317	248	15	staining	stain	VERB
admet-1317	248	16	with	with	ADP
admet-1317	248	17	methylene	methylene	ADJ
admet-1317	248	18	blue	blue	ADJ
admet-1317	248	19	dye	dye	NOUN
admet-1317	248	20	showing	show	VERB
admet-1317	248	21	the	the	DET
admet-1317	248	22	pores	pore	NOUN
admet-1317	248	23	formed	form	VERB
admet-1317	248	24	by	by	ADP
admet-1317	248	25	different	different	ADJ
admet-1317	248	26	formulas	formula	NOUN
admet-1317	248	27	,	,	PUNCT
admet-1317	248	28	where	where	SCONJ
admet-1317	248	29	(	(	PUNCT
admet-1317	248	30	a	a	X
admet-1317	248	31	)	)	PUNCT
admet-1317	248	32	represents	represent	VERB
admet-1317	248	33	f11	f11	PROPN
admet-1317	248	34	,	,	PUNCT
admet-1317	248	35	(	(	PUNCT
admet-1317	248	36	b	b	NOUN
admet-1317	248	37	)	)	PUNCT
admet-1317	248	38	f10	f10	NOUN
admet-1317	248	39	,	,	PUNCT
admet-1317	248	40	(	(	PUNCT
admet-1317	248	41	c	c	X
admet-1317	248	42	)	)	PUNCT
admet-1317	248	43	f9	f9	PROPN
admet-1317	248	44	and	and	CCONJ
admet-1317	248	45	(	(	PUNCT
admet-1317	248	46	d	d	NOUN
admet-1317	248	47	)	)	PUNCT
admet-1317	248	48	f8	f8	PROPN
admet-1317	248	49	.	.	PUNCT
admet-1317	249	1	characterisation	characterisation	NOUN
admet-1317	249	2	of	of	ADP
admet-1317	249	3	the	the	DET
admet-1317	249	4	optimum	optimum	ADJ
admet-1317	249	5	formula	formula	NOUN
admet-1317	249	6	ha	ha	INTJ
admet-1317	249	7	mn	mn	PROPN
admet-1317	249	8	array	array	PROPN
admet-1317	249	9	formula	formula	NOUN
admet-1317	249	10	f11	f11	PROPN
admet-1317	249	11	was	be	AUX
admet-1317	249	12	identified	identify	VERB
admet-1317	249	13	as	as	ADP
admet-1317	249	14	the	the	DET
admet-1317	249	15	optimum	optimum	ADJ
admet-1317	249	16	formula	formula	NOUN
admet-1317	249	17	because	because	SCONJ
admet-1317	249	18	it	it	PRON
admet-1317	249	19	showed	show	VERB
admet-1317	249	20	the	the	DET
admet-1317	249	21	required	require	VERB
admet-1317	249	22	mechanical	mechanical	ADJ
admet-1317	249	23	strength	strength	NOUN
admet-1317	249	24	,	,	PUNCT
admet-1317	249	25	high	high	ADJ
admet-1317	249	26	drug	drug	NOUN
admet-1317	249	27	content	content	NOUN
admet-1317	249	28	(	(	PUNCT
admet-1317	249	29	data	datum	NOUN
admet-1317	249	30	not	not	PART
admet-1317	249	31	shown	show	VERB
admet-1317	249	32	)	)	PUNCT
admet-1317	249	33	and	and	CCONJ
admet-1317	249	34	superior	superior	ADJ
admet-1317	249	35	penetration	penetration	NOUN
admet-1317	249	36	into	into	ADP
admet-1317	249	37	the	the	DET
admet-1317	249	38	skin	skin	NOUN
admet-1317	249	39	surface	surface	NOUN
admet-1317	249	40	.	.	PUNCT
admet-1317	250	1	(	(	PUNCT
admet-1317	250	2	i.e.	i.e.	X
admet-1317	250	3	highest	high	ADJ
admet-1317	250	4	insertion	insertion	NOUN
admet-1317	250	5	capability	capability	NOUN
admet-1317	250	6	)	)	PUNCT
admet-1317	250	7	,	,	PUNCT
admet-1317	250	8	in	in	ADP
admet-1317	250	9	addition	addition	NOUN
admet-1317	250	10	to	to	ADP
admet-1317	250	11	its	its	PRON
admet-1317	250	12	ease	ease	NOUN
admet-1317	250	13	of	of	ADP
admet-1317	250	14	formulation	formulation	NOUN
admet-1317	250	15	during	during	ADP
admet-1317	250	16	the	the	DET
admet-1317	250	17	fabrication	fabrication	NOUN
admet-1317	250	18	process	process	NOUN
admet-1317	250	19	and	and	CCONJ
admet-1317	250	20	elegant	elegant	ADJ
admet-1317	250	21	appearance	appearance	NOUN
admet-1317	250	22	.	.	PUNCT
admet-1317	251	1	therefore	therefore	ADV
admet-1317	251	2	,	,	PUNCT
admet-1317	251	3	the	the	DET
admet-1317	251	4	f11	f11	NOUN
admet-1317	251	5	formula	formula	NOUN
admet-1317	251	6	was	be	AUX
admet-1317	251	7	subjected	subject	VERB
admet-1317	251	8	to	to	ADP
admet-1317	251	9	further	further	ADJ
admet-1317	251	10	investigations	investigation	NOUN
admet-1317	251	11	to	to	PART
admet-1317	251	12	ensure	ensure	VERB
admet-1317	251	13	its	its	PRON
admet-1317	251	14	eligibility	eligibility	NOUN
admet-1317	251	15	as	as	ADP
admet-1317	251	16	a	a	DET
admet-1317	251	17	transdermal	transdermal	ADJ
admet-1317	251	18	drug	drug	NOUN
admet-1317	251	19	delivery	delivery	NOUN
admet-1317	251	20	system	system	NOUN
admet-1317	251	21	for	for	ADP
admet-1317	251	22	lt-4	lt-4	NOUN
admet-1317	251	23	sodium	sodium	NOUN
admet-1317	251	24	.	.	PUNCT
admet-1317	252	1	histological	histological	ADJ
admet-1317	252	2	examination	examination	NOUN
admet-1317	252	3	of	of	ADP
admet-1317	252	4	mn	mn	PROPN
admet-1317	252	5	treated	treat	VERB
admet-1317	252	6	skin	skin	NOUN
admet-1317	252	7	to	to	PART
admet-1317	252	8	demonstrate	demonstrate	VERB
admet-1317	252	9	the	the	DET
admet-1317	252	10	penetration	penetration	NOUN
admet-1317	252	11	depth	depth	NOUN
admet-1317	252	12	of	of	ADP
admet-1317	252	13	the	the	DET
admet-1317	252	14	microchannels	microchannel	NOUN
admet-1317	252	15	within	within	ADP
admet-1317	252	16	skin	skin	NOUN
admet-1317	252	17	layers	layer	NOUN
admet-1317	252	18	achieved	achieve	VERB
admet-1317	252	19	by	by	ADP
admet-1317	252	20	the	the	DET
admet-1317	252	21	application	application	NOUN
admet-1317	252	22	of	of	ADP
admet-1317	252	23	mn	mn	PROPN
admet-1317	252	24	arrays	array	VERB
admet-1317	252	25	,	,	PUNCT
admet-1317	252	26	histological	histological	ADJ
admet-1317	252	27	examination	examination	NOUN
admet-1317	252	28	of	of	ADP
admet-1317	252	29	the	the	DET
admet-1317	252	30	cross	cross	NOUN
admet-1317	252	31	-	-	ADJ
admet-1317	252	32	sectioned	sectioned	ADJ
admet-1317	252	33	and	and	CCONJ
admet-1317	252	34	stained	stain	VERB
admet-1317	252	35	human	human	ADJ
admet-1317	252	36	skin	skin	NOUN
admet-1317	252	37	samples	sample	NOUN
admet-1317	252	38	was	be	AUX
admet-1317	252	39	performed	perform	VERB
admet-1317	252	40	as	as	SCONJ
admet-1317	252	41	shown	show	VERB
admet-1317	252	42	in	in	ADP
admet-1317	252	43	figures	figure	NOUN
admet-1317	252	44	6	6	NUM
admet-1317	252	45	(	(	PUNCT
admet-1317	252	46	a	a	NOUN
admet-1317	252	47	)	)	PUNCT
admet-1317	252	48	and	and	CCONJ
admet-1317	252	49	(	(	PUNCT
admet-1317	252	50	b	b	NOUN
admet-1317	252	51	)	)	PUNCT
admet-1317	252	52	.	.	PUNCT
admet-1317	253	1	it	it	PRON
admet-1317	253	2	can	can	AUX
admet-1317	253	3	be	be	AUX
admet-1317	253	4	observed	observe	VERB
admet-1317	253	5	that	that	SCONJ
admet-1317	253	6	f11	f11	PROPN
admet-1317	253	7	mn	mn	PROPN
admet-1317	253	8	arrays	array	VERB
admet-1317	253	9	following	follow	VERB
admet-1317	253	10	the	the	DET
admet-1317	253	11	insertion	insertion	NOUN
admet-1317	253	12	into	into	ADP
admet-1317	253	13	the	the	DET
admet-1317	253	14	skin	skin	NOUN
admet-1317	253	15	have	have	AUX
admet-1317	253	16	developed	develop	VERB
admet-1317	253	17	drug	drug	NOUN
admet-1317	253	18	microchannels	microchannel	NOUN
admet-1317	253	19	(	(	PUNCT
admet-1317	253	20	drug	drug	NOUN
admet-1317	253	21	permeation	permeation	NOUN
admet-1317	253	22	routes	route	NOUN
admet-1317	253	23	)	)	PUNCT
admet-1317	253	24	through	through	ADP
admet-1317	253	25	the	the	DET
admet-1317	253	26	different	different	ADJ
admet-1317	253	27	skin	skin	NOUN
admet-1317	253	28	layers	layer	NOUN
admet-1317	253	29	,	,	PUNCT
admet-1317	253	30	including	include	VERB
admet-1317	253	31	the	the	DET
admet-1317	253	32	stratum	stratum	NOUN
admet-1317	253	33	corneum	corneum	NOUN
admet-1317	253	34	,	,	PUNCT
admet-1317	253	35	viable	viable	ADJ
admet-1317	253	36	epidermis	epidermis	NOUN
admet-1317	253	37	and	and	CCONJ
admet-1317	253	38	dermis	dermis	NOUN
admet-1317	253	39	.	.	PUNCT
admet-1317	254	1	these	these	DET
admet-1317	254	2	microchannels	microchannel	NOUN
admet-1317	254	3	formed	form	VERB
admet-1317	254	4	in	in	ADP
admet-1317	254	5	the	the	DET
admet-1317	254	6	skin	skin	NOUN
admet-1317	254	7	showed	show	VERB
admet-1317	254	8	approximately	approximately	ADV
admet-1317	254	9	similar	similar	ADJ
admet-1317	254	10	shapes	shape	NOUN
admet-1317	254	11	to	to	ADP
admet-1317	254	12	the	the	DET
admet-1317	254	13	inserted	insert	VERB
admet-1317	254	14	mns	mns	PROPN
admet-1317	254	15	arrays	array	NOUN
admet-1317	254	16	indicating	indicate	VERB
admet-1317	254	17	their	their	PRON
admet-1317	254	18	uniform	uniform	ADJ
admet-1317	254	19	insertion	insertion	NOUN
admet-1317	254	20	.	.	PUNCT
admet-1317	255	1	it	it	PRON
admet-1317	255	2	is	be	AUX
admet-1317	255	3	believed	believe	VERB
admet-1317	255	4	that	that	SCONJ
admet-1317	255	5	these	these	DET
admet-1317	255	6	microchannels	microchannel	NOUN
admet-1317	255	7	play	play	VERB
admet-1317	255	8	a	a	DET
admet-1317	255	9	significant	significant	ADJ
admet-1317	255	10	role	role	NOUN
admet-1317	255	11	in	in	ADP
admet-1317	255	12	the	the	DET
admet-1317	255	13	permeation	permeation	NOUN
admet-1317	255	14	of	of	ADP
admet-1317	255	15	lt-4	lt-4	NOUN
admet-1317	255	16	sodium	sodium	NOUN
admet-1317	255	17	into	into	ADP
admet-1317	255	18	the	the	DET
admet-1317	255	19	systemic	systemic	ADJ
admet-1317	255	20	circulation	circulation	NOUN
admet-1317	255	21	by	by	ADP
admet-1317	255	22	bypassing	bypass	VERB
admet-1317	255	23	the	the	DET
admet-1317	255	24	stratum	stratum	NOUN
admet-1317	255	25	corneum	corneum	NOUN
admet-1317	255	26	barrier	barrier	NOUN
admet-1317	255	27	.	.	PUNCT
admet-1317	256	1	in	in	ADP
admet-1317	256	2	addition	addition	NOUN
admet-1317	256	3	,	,	PUNCT
admet-1317	256	4	figure	figure	NOUN
admet-1317	256	5	6	6	NUM
admet-1317	256	6	(	(	PUNCT
admet-1317	256	7	a	a	NOUN
admet-1317	256	8	)	)	PUNCT
admet-1317	256	9	highlights	highlight	NOUN
admet-1317	256	10	the	the	DET
admet-1317	256	11	difference	difference	NOUN
admet-1317	256	12	in	in	ADP
admet-1317	256	13	size	size	NOUN
admet-1317	256	14	between	between	ADP
admet-1317	256	15	pores	pore	NOUN
admet-1317	256	16	created	create	VERB
admet-1317	256	17	by	by	ADP
admet-1317	256	18	the	the	DET
admet-1317	256	19	mn	mn	PROPN
admet-1317	256	20	arrays	array	VERB
admet-1317	256	21	and	and	CCONJ
admet-1317	256	22	by	by	ADP
admet-1317	256	23	the	the	DET
admet-1317	256	24	traditional	traditional	ADJ
admet-1317	256	25	hypodermic	hypodermic	ADJ
admet-1317	256	26	syringe	syringe	NOUN
admet-1317	256	27	.	.	PUNCT
admet-1317	257	1	the	the	DET
admet-1317	257	2	pores	pore	NOUN
admet-1317	257	3	formed	form	VERB
admet-1317	257	4	by	by	ADP
admet-1317	257	5	hypodermic	hypodermic	ADJ
admet-1317	257	6	needles	needle	NOUN
admet-1317	257	7	are	be	AUX
admet-1317	257	8	obviously	obviously	ADV
admet-1317	257	9	larger	large	ADJ
admet-1317	257	10	,	,	PUNCT
admet-1317	257	11	deeper	deeply	ADV
admet-1317	257	12	reaching	reach	VERB
admet-1317	257	13	the	the	DET
admet-1317	257	14	deep	deep	ADJ
admet-1317	257	15	dermis	dermis	NOUN
admet-1317	257	16	and	and	CCONJ
admet-1317	257	17	having	have	VERB
admet-1317	257	18	a	a	DET
admet-1317	257	19	greater	great	ADJ
admet-1317	257	20	opportunity	opportunity	NOUN
admet-1317	257	21	to	to	PART
admet-1317	257	22	stimulate	stimulate	VERB
admet-1317	257	23	the	the	DET
admet-1317	257	24	nerve	nerve	NOUN
admet-1317	257	25	endings	ending	NOUN
admet-1317	257	26	than	than	ADP
admet-1317	257	27	those	those	PRON
admet-1317	257	28	formed	form	VERB
admet-1317	257	29	by	by	ADP
admet-1317	257	30	mns	mns	PROPN
admet-1317	257	31	.	.	PUNCT
admet-1317	258	1	ultimately	ultimately	ADV
admet-1317	258	2	,	,	PUNCT
admet-1317	258	3	these	these	DET
admet-1317	258	4	observations	observation	NOUN
admet-1317	258	5	suggested	suggest	VERB
admet-1317	258	6	that	that	SCONJ
admet-1317	258	7	f11	f11	PROPN
admet-1317	258	8	mn	mn	PROPN
admet-1317	258	9	arrays	array	VERB
admet-1317	258	10	have	have	VERB
admet-1317	258	11	the	the	DET
admet-1317	258	12	potential	potential	NOUN
admet-1317	258	13	for	for	ADP
admet-1317	258	14	successful	successful	ADJ
admet-1317	258	15	transdermal	transdermal	ADJ
admet-1317	258	16	delivery	delivery	NOUN
admet-1317	258	17	of	of	ADP
admet-1317	258	18	lt-4	lt-4	NOUN
admet-1317	258	19	sodium	sodium	NOUN
admet-1317	258	20	across	across	ADP
admet-1317	258	21	the	the	DET
admet-1317	258	22	skin	skin	NOUN
admet-1317	258	23	with	with	ADP
admet-1317	258	24	a	a	DET
admet-1317	258	25	little	little	ADJ
admet-1317	258	26	tendency	tendency	NOUN
admet-1317	258	27	to	to	PART
admet-1317	258	28	trigger	trigger	VERB
admet-1317	258	29	the	the	DET
admet-1317	258	30	nerve	nerve	NOUN
admet-1317	258	31	endings	ending	NOUN
admet-1317	258	32	located	locate	VERB
admet-1317	258	33	at	at	ADP
admet-1317	258	34	the	the	DET
admet-1317	258	35	deep	deep	ADJ
admet-1317	258	36	dermis	dermis	NOUN
admet-1317	258	37	layer	layer	NOUN
admet-1317	259	1	[	[	X
admet-1317	259	2	43	43	NUM
admet-1317	259	3	]	]	PUNCT
admet-1317	259	4	.	.	PUNCT
admet-1317	260	1	in	in	ADP
admet-1317	260	2	vivo	vivo	ADJ
admet-1317	260	3	dissolution	dissolution	NOUN
admet-1317	260	4	of	of	ADP
admet-1317	260	5	mn	mn	PROPN
admet-1317	260	6	arrays	array	VERB
admet-1317	260	7	.	.	PUNCT
admet-1317	261	1	the	the	DET
admet-1317	261	2	images	image	NOUN
admet-1317	261	3	of	of	ADP
admet-1317	261	4	the	the	DET
admet-1317	261	5	in	in	ADP
admet-1317	261	6	vivo	vivo	ADJ
admet-1317	261	7	dissolution	dissolution	NOUN
admet-1317	261	8	study	study	NOUN
admet-1317	261	9	of	of	ADP
admet-1317	261	10	f11	f11	PROPN
admet-1317	261	11	mn	mn	PROPN
admet-1317	261	12	arrays	array	VERB
admet-1317	261	13	within	within	ADP
admet-1317	261	14	rat	rat	NOUN
admet-1317	261	15	skin	skin	NOUN
admet-1317	261	16	are	be	AUX
admet-1317	261	17	illustrated	illustrate	VERB
admet-1317	261	18	in	in	ADP
admet-1317	261	19	figure	figure	NOUN
admet-1317	261	20	7	7	NUM
admet-1317	261	21	.	.	PUNCT
admet-1317	261	22	as	as	SCONJ
admet-1317	261	23	depicted	depict	VERB
admet-1317	261	24	in	in	ADP
admet-1317	261	25	the	the	DET
admet-1317	261	26	images	image	NOUN
admet-1317	261	27	,	,	PUNCT
admet-1317	261	28	the	the	DET
admet-1317	261	29	dissolution	dissolution	NOUN
admet-1317	261	30	of	of	ADP
admet-1317	261	31	the	the	DET
admet-1317	261	32	mn	mn	PROPN
admet-1317	261	33	arrays	array	NOUN
admet-1317	261	34	was	be	AUX
admet-1317	261	35	very	very	ADV
admet-1317	261	36	fast	fast	ADJ
admet-1317	261	37	,	,	PUNCT
admet-1317	261	38	starting	start	VERB
admet-1317	261	39	5	5	NUM
admet-1317	261	40	minutes	minute	NOUN
admet-1317	261	41	after	after	ADP
admet-1317	261	42	insertion	insertion	NOUN
admet-1317	261	43	into	into	ADP
admet-1317	261	44	the	the	DET
admet-1317	261	45	skin	skin	NOUN
admet-1317	261	46	,	,	PUNCT
admet-1317	261	47	with	with	ADP
admet-1317	261	48	complete	complete	ADJ
admet-1317	261	49	dissolution	dissolution	NOUN
admet-1317	261	50	achieved	achieve	VERB
admet-1317	261	51	by	by	ADP
admet-1317	261	52	1	1	NUM
admet-1317	261	53	hour	hour	NOUN
admet-1317	261	54	.	.	PUNCT
admet-1317	262	1	the	the	DET
admet-1317	262	2	fast	fast	ADJ
admet-1317	262	3	dissolution	dissolution	NOUN
admet-1317	262	4	of	of	ADP
admet-1317	262	5	f11	f11	PROPN
admet-1317	262	6	mns	mns	PROPN
admet-1317	262	7	suggests	suggest	VERB
admet-1317	262	8	rapid	rapid	ADJ
admet-1317	262	9	delivery	delivery	NOUN
admet-1317	262	10	of	of	ADP
admet-1317	262	11	lt-4	lt-4	NOUN
admet-1317	262	12	sodium	sodium	NOUN
admet-1317	262	13	across	across	ADP
admet-1317	262	14	the	the	DET
admet-1317	262	15	skin	skin	NOUN
admet-1317	262	16	layers	layer	NOUN
admet-1317	262	17	.	.	PUNCT
admet-1317	263	1	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	VERB
admet-1317	264	1	r.f	r.f	PROPN
admet-1317	264	2	.	.	PROPN
admet-1317	264	3	ghazi	ghazi	PROPN
admet-1317	264	4	and	and	CCONJ
admet-1317	264	5	m.h	m.h	PROPN
admet-1317	264	6	.	.	PROPN
admet-1317	264	7	al	al	PROPN
admet-1317	264	8	-	-	PUNCT
admet-1317	264	9	mayahy	mayahy	PROPN
admet-1317	264	10	admet	admet	PROPN
admet-1317	264	11	&	&	CCONJ
admet-1317	264	12	dmpk	dmpk	PROPN
admet-1317	264	13	10(3	10(3	NUM
admet-1317	264	14	)	)	PUNCT
admet-1317	264	15	(	(	PUNCT
admet-1317	264	16	2022	2022	NUM
admet-1317	264	17	)	)	PUNCT
admet-1317	264	18	213	213	NUM
admet-1317	264	19	-	-	SYM
admet-1317	264	20	230	230	NUM
admet-1317	264	21	224	224	NUM
admet-1317	264	22	it	it	PRON
admet-1317	264	23	has	have	AUX
admet-1317	264	24	been	be	AUX
admet-1317	264	25	observed	observe	VERB
admet-1317	264	26	that	that	SCONJ
admet-1317	264	27	ha	ha	INTJ
admet-1317	264	28	mns	mns	PROPN
admet-1317	264	29	possess	possess	VERB
admet-1317	264	30	self	self	NOUN
admet-1317	264	31	-	-	PUNCT
admet-1317	264	32	dissolving	dissolve	VERB
admet-1317	264	33	properties	property	NOUN
admet-1317	264	34	and	and	CCONJ
admet-1317	264	35	are	be	AUX
admet-1317	264	36	easily	easily	ADV
admet-1317	264	37	dissolved	dissolve	VERB
admet-1317	264	38	upon	upon	SCONJ
admet-1317	264	39	application	application	NOUN
admet-1317	264	40	to	to	ADP
admet-1317	264	41	the	the	DET
admet-1317	264	42	skin	skin	NOUN
admet-1317	264	43	[	[	X
admet-1317	264	44	20	20	NUM
admet-1317	264	45	]	]	PUNCT
admet-1317	264	46	.	.	PUNCT
admet-1317	265	1	this	this	DET
admet-1317	265	2	rapid	rapid	ADJ
admet-1317	265	3	dissolution	dissolution	NOUN
admet-1317	265	4	is	be	AUX
admet-1317	265	5	caused	cause	VERB
admet-1317	265	6	by	by	ADP
admet-1317	265	7	the	the	DET
admet-1317	265	8	high	high	ADJ
admet-1317	265	9	hydrophilicity	hydrophilicity	NOUN
admet-1317	265	10	of	of	ADP
admet-1317	265	11	ha	ha	INTJ
admet-1317	265	12	[	[	X
admet-1317	265	13	44	44	NUM
admet-1317	265	14	]	]	PUNCT
admet-1317	265	15	.	.	PUNCT
admet-1317	266	1	in	in	ADP
admet-1317	266	2	their	their	PRON
admet-1317	266	3	research	research	NOUN
admet-1317	266	4	study	study	NOUN
admet-1317	266	5	,	,	PUNCT
admet-1317	266	6	zhuangzhi	zhuangzhi	PROPN
admet-1317	266	7	zhu	zhu	PROPN
admet-1317	266	8	et	et	PROPN
admet-1317	266	9	al	al	PROPN
admet-1317	266	10	.	.	PROPN
admet-1317	266	11	,	,	PUNCT
admet-1317	266	12	have	have	AUX
admet-1317	266	13	shown	show	VERB
admet-1317	266	14	that	that	SCONJ
admet-1317	266	15	ha	ha	INTJ
admet-1317	266	16	is	be	AUX
admet-1317	266	17	a	a	DET
admet-1317	266	18	suitable	suitable	ADJ
admet-1317	266	19	candidate	candidate	NOUN
admet-1317	266	20	for	for	ADP
admet-1317	266	21	dissolving	dissolve	VERB
admet-1317	266	22	mns	mn	NOUN
admet-1317	266	23	,	,	PUNCT
admet-1317	266	24	as	as	SCONJ
admet-1317	266	25	it	it	PRON
admet-1317	266	26	starts	start	VERB
admet-1317	266	27	dissolving	dissolve	VERB
admet-1317	266	28	rapidly	rapidly	ADV
admet-1317	266	29	upon	upon	SCONJ
admet-1317	266	30	application	application	NOUN
admet-1317	266	31	into	into	ADP
admet-1317	266	32	the	the	DET
admet-1317	266	33	skin	skin	NOUN
admet-1317	266	34	,	,	PUNCT
admet-1317	266	35	proposing	propose	VERB
admet-1317	266	36	that	that	SCONJ
admet-1317	266	37	it	it	PRON
admet-1317	266	38	required	require	VERB
admet-1317	266	39	60	60	NUM
admet-1317	266	40	120	120	NUM
admet-1317	266	41	minutes	minute	NOUN
admet-1317	266	42	for	for	SCONJ
admet-1317	266	43	their	their	PRON
admet-1317	266	44	needles	needle	NOUN
admet-1317	266	45	to	to	PART
admet-1317	266	46	be	be	AUX
admet-1317	266	47	completely	completely	ADV
admet-1317	266	48	dissolved	dissolve	VERB
admet-1317	266	49	in	in	ADP
admet-1317	266	50	the	the	DET
admet-1317	266	51	skin	skin	NOUN
admet-1317	266	52	[	[	X
admet-1317	266	53	44	44	NUM
admet-1317	266	54	]	]	PUNCT
admet-1317	266	55	.	.	PUNCT
admet-1317	267	1	figure	figure	NOUN
admet-1317	267	2	6	6	NUM
admet-1317	267	3	.	.	PUNCT
admet-1317	268	1	digital	digital	ADJ
admet-1317	268	2	microscope	microscope	NOUN
admet-1317	268	3	images	image	NOUN
admet-1317	268	4	of	of	ADP
admet-1317	268	5	cross	cross	ADJ
admet-1317	268	6	-	-	ADJ
admet-1317	268	7	sectioned	sectioned	ADJ
admet-1317	268	8	human	human	ADJ
admet-1317	268	9	skin	skin	NOUN
admet-1317	268	10	samples	sample	NOUN
admet-1317	268	11	stained	stain	VERB
admet-1317	268	12	with	with	ADP
admet-1317	268	13	h&e	h&e	PROPN
admet-1317	268	14	for	for	ADP
admet-1317	268	15	mn	mn	PROPN
admet-1317	268	16	treated	treat	VERB
admet-1317	268	17	skin	skin	NOUN
admet-1317	268	18	(	(	PUNCT
admet-1317	268	19	a	a	NOUN
admet-1317	268	20	)	)	PUNCT
admet-1317	268	21	at	at	ADP
admet-1317	268	22	power	power	NOUN
admet-1317	268	23	4x	4x	PROPN
admet-1317	268	24	and	and	CCONJ
admet-1317	268	25	(	(	PUNCT
admet-1317	268	26	b	b	NOUN
admet-1317	268	27	)	)	PUNCT
admet-1317	268	28	at	at	ADP
admet-1317	268	29	power	power	NOUN
admet-1317	268	30	10x	10x	NUM
admet-1317	268	31	;	;	PUNCT
admet-1317	268	32	demonstrating	demonstrate	VERB
admet-1317	268	33	the	the	DET
admet-1317	268	34	location	location	NOUN
admet-1317	268	35	of	of	ADP
admet-1317	268	36	microchannels	microchannel	NOUN
admet-1317	268	37	within	within	ADP
admet-1317	268	38	the	the	DET
admet-1317	268	39	skin	skin	NOUN
admet-1317	268	40	in	in	ADP
admet-1317	268	41	comparison	comparison	NOUN
admet-1317	268	42	to	to	ADP
admet-1317	268	43	the	the	DET
admet-1317	268	44	hypodermic	hypodermic	ADJ
admet-1317	268	45	needle	needle	NOUN
admet-1317	268	46	.	.	PUNCT
admet-1317	269	1	where	where	SCONJ
admet-1317	269	2	:	:	PUNCT
admet-1317	269	3	(	(	PUNCT
admet-1317	269	4	sc	sc	NOUN
admet-1317	269	5	)	)	PUNCT
admet-1317	269	6	represents	represent	VERB
admet-1317	269	7	stratum	stratum	PROPN
admet-1317	269	8	corneum	corneum	NOUN
admet-1317	269	9	,	,	PUNCT
admet-1317	269	10	(	(	PUNCT
admet-1317	269	11	ve	ve	NOUN
admet-1317	269	12	)	)	PUNCT
admet-1317	269	13	viable	viable	ADJ
admet-1317	269	14	epidermis	epidermis	NOUN
admet-1317	269	15	and	and	CCONJ
admet-1317	269	16	(	(	PUNCT
admet-1317	269	17	d	d	NOUN
admet-1317	269	18	)	)	PUNCT
admet-1317	269	19	dermis	dermis	NOUN
admet-1317	269	20	.	.	PUNCT
admet-1317	270	1	figure	figure	NOUN
admet-1317	270	2	7	7	NUM
admet-1317	270	3	.	.	NOUN
admet-1317	270	4	time	time	NOUN
admet-1317	270	5	-	-	PUNCT
admet-1317	270	6	course	course	NOUN
admet-1317	270	7	images	image	NOUN
admet-1317	270	8	of	of	ADP
admet-1317	270	9	f11	f11	PROPN
admet-1317	270	10	mn	mn	PROPN
admet-1317	270	11	arrays	array	VERB
admet-1317	270	12	after	after	ADP
admet-1317	270	13	being	be	AUX
admet-1317	270	14	applied	apply	VERB
admet-1317	270	15	to	to	ADP
admet-1317	270	16	the	the	DET
admet-1317	270	17	skin	skin	NOUN
admet-1317	270	18	of	of	ADP
admet-1317	270	19	a	a	DET
admet-1317	270	20	live	live	ADJ
admet-1317	270	21	rat	rat	NOUN
admet-1317	270	22	and	and	CCONJ
admet-1317	270	23	withdrawn	withdraw	VERB
admet-1317	270	24	at	at	ADP
admet-1317	270	25	the	the	DET
admet-1317	270	26	indicated	indicate	VERB
admet-1317	270	27	time	time	NOUN
admet-1317	270	28	points	point	NOUN
admet-1317	270	29	.	.	PUNCT
admet-1317	271	1	admet	admet	PROPN
admet-1317	271	2	&	&	CCONJ
admet-1317	271	3	dmpk	dmpk	PROPN
admet-1317	271	4	10(3	10(3	NUM
admet-1317	271	5	)	)	PUNCT
admet-1317	271	6	(	(	PUNCT
admet-1317	271	7	2022	2022	NUM
admet-1317	271	8	)	)	PUNCT
admet-1317	271	9	213	213	NUM
admet-1317	271	10	-	-	SYM
admet-1317	271	11	230	230	NUM
admet-1317	271	12	transdermal	transdermal	ADJ
admet-1317	271	13	delivery	delivery	NOUN
admet-1317	271	14	of	of	ADP
admet-1317	271	15	levothyroxine	levothyroxine	NOUN
admet-1317	271	16	via	via	ADP
admet-1317	271	17	dissolving	dissolve	VERB
admet-1317	271	18	microneedles	microneedle	NOUN
admet-1317	271	19	doi	doi	PROPN
admet-1317	271	20	:	:	PUNCT
admet-1317	271	21	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	NUM
admet-1317	271	22	225	225	NUM
admet-1317	271	23	visualization	visualization	NOUN
admet-1317	271	24	of	of	ADP
admet-1317	271	25	microneedles	microneedle	NOUN
admet-1317	271	26	by	by	ADP
admet-1317	271	27	scanning	scan	VERB
admet-1317	271	28	electron	electron	NOUN
admet-1317	271	29	microscopy	microscopy	NOUN
admet-1317	271	30	(	(	PUNCT
admet-1317	271	31	sem	sem	NOUN
admet-1317	271	32	)	)	PUNCT
admet-1317	271	33	the	the	DET
admet-1317	271	34	sem	sem	NOUN
admet-1317	271	35	images	image	NOUN
admet-1317	271	36	of	of	ADP
admet-1317	271	37	f11	f11	PROPN
admet-1317	271	38	mn	mn	PROPN
admet-1317	271	39	array	array	NOUN
admet-1317	271	40	are	be	AUX
admet-1317	271	41	demonstrated	demonstrate	VERB
admet-1317	271	42	in	in	ADP
admet-1317	271	43	figure	figure	NOUN
admet-1317	271	44	8	8	NUM
admet-1317	271	45	.	.	PUNCT
admet-1317	272	1	the	the	DET
admet-1317	272	2	images	image	NOUN
admet-1317	272	3	highlight	highlight	VERB
admet-1317	272	4	the	the	DET
admet-1317	272	5	proper	proper	ADJ
admet-1317	272	6	formation	formation	NOUN
admet-1317	272	7	of	of	ADP
admet-1317	272	8	sharp	sharp	ADJ
admet-1317	272	9	,	,	PUNCT
admet-1317	272	10	pyramidal	pyramidal	NOUN
admet-1317	272	11	-	-	PUNCT
admet-1317	272	12	shaped	shape	VERB
admet-1317	272	13	and	and	CCONJ
admet-1317	272	14	equally	equally	ADV
admet-1317	272	15	interspaced	interspace	VERB
admet-1317	272	16	mns	mn	NOUN
admet-1317	272	17	.	.	PUNCT
admet-1317	273	1	additionally	additionally	ADV
admet-1317	273	2	,	,	PUNCT
admet-1317	273	3	the	the	DET
admet-1317	273	4	images	image	NOUN
admet-1317	273	5	elucidate	elucidate	VERB
admet-1317	273	6	the	the	DET
admet-1317	273	7	dimensions	dimension	NOUN
admet-1317	273	8	of	of	ADP
admet-1317	273	9	mns	mns	PROPN
admet-1317	273	10	.	.	PUNCT
admet-1317	274	1	for	for	ADP
admet-1317	274	2	example	example	NOUN
admet-1317	274	3	,	,	PUNCT
admet-1317	274	4	an	an	DET
admet-1317	274	5	individual	individual	ADJ
admet-1317	274	6	mn	mn	PROPN
admet-1317	274	7	from	from	ADP
admet-1317	274	8	the	the	DET
admet-1317	274	9	array	array	NOUN
admet-1317	274	10	showed	show	VERB
admet-1317	274	11	a	a	DET
admet-1317	274	12	mean	mean	ADJ
admet-1317	274	13	length	length	NOUN
admet-1317	274	14	of	of	ADP
admet-1317	274	15	432.0	432.0	NUM
admet-1317	274	16	±	±	NUM
admet-1317	274	17	6.4	6.4	NUM
admet-1317	274	18	μm	μm	NOUN
admet-1317	274	19	.	.	PUNCT
admet-1317	275	1	the	the	DET
admet-1317	275	2	needle	needle	NOUN
admet-1317	275	3	tip	tip	NOUN
admet-1317	275	4	diameter	diameter	NOUN
admet-1317	275	5	of	of	ADP
admet-1317	275	6	9.8	9.8	NUM
admet-1317	275	7	±	±	NUM
admet-1317	275	8	1.3	1.3	NUM
admet-1317	275	9	μm	μm	NOUN
admet-1317	275	10	,	,	PUNCT
admet-1317	275	11	base	base	NOUN
admet-1317	275	12	diameter	diameter	NOUN
admet-1317	275	13	of	of	ADP
admet-1317	275	14	288	288	NUM
admet-1317	275	15	±	±	NUM
admet-1317	275	16	2.2	2.2	NUM
admet-1317	275	17	μm	μm	NOUN
admet-1317	275	18	and	and	CCONJ
admet-1317	275	19	interspacing	interspace	VERB
admet-1317	275	20	distance	distance	NOUN
admet-1317	275	21	(	(	PUNCT
admet-1317	275	22	the	the	DET
admet-1317	275	23	distance	distance	NOUN
admet-1317	275	24	between	between	ADP
admet-1317	275	25	two	two	NUM
admet-1317	275	26	needle	needle	NOUN
admet-1317	275	27	tips	tip	NOUN
admet-1317	275	28	)	)	PUNCT
admet-1317	275	29	of	of	ADP
admet-1317	275	30	500.0	500.0	NUM
admet-1317	275	31	±	±	NUM
admet-1317	275	32	5.5	5.5	NUM
admet-1317	275	33	μm	μm	NOUN
admet-1317	275	34	.	.	PUNCT
admet-1317	276	1	based	base	VERB
admet-1317	276	2	on	on	ADP
admet-1317	276	3	these	these	DET
admet-1317	276	4	dimensions	dimension	NOUN
admet-1317	276	5	,	,	PUNCT
admet-1317	276	6	the	the	DET
admet-1317	276	7	mns	mns	PROPN
admet-1317	276	8	possess	possess	VERB
admet-1317	276	9	sharp	sharp	ADJ
admet-1317	276	10	tips	tip	NOUN
admet-1317	276	11	with	with	ADP
admet-1317	276	12	a	a	DET
admet-1317	276	13	strong	strong	ADJ
admet-1317	276	14	base	base	NOUN
admet-1317	276	15	required	require	VERB
admet-1317	276	16	for	for	ADP
admet-1317	276	17	successful	successful	ADJ
admet-1317	276	18	penetration	penetration	NOUN
admet-1317	276	19	into	into	ADP
admet-1317	276	20	the	the	DET
admet-1317	276	21	skin	skin	NOUN
admet-1317	276	22	[	[	X
admet-1317	276	23	32	32	NUM
admet-1317	276	24	]	]	PUNCT
admet-1317	276	25	.	.	PUNCT
admet-1317	277	1	according	accord	VERB
admet-1317	277	2	to	to	ADP
admet-1317	277	3	the	the	DET
admet-1317	277	4	sem	sem	NOUN
admet-1317	277	5	images	image	NOUN
admet-1317	277	6	,	,	PUNCT
admet-1317	277	7	the	the	DET
admet-1317	277	8	prepared	prepare	VERB
admet-1317	277	9	ha	ha	INTJ
admet-1317	277	10	mn	mn	PROPN
admet-1317	277	11	by	by	ADP
admet-1317	277	12	micromoulding	micromoulde	VERB
admet-1317	277	13	technique	technique	NOUN
admet-1317	277	14	were	be	AUX
admet-1317	277	15	shorter	short	ADJ
admet-1317	277	16	than	than	ADP
admet-1317	277	17	the	the	DET
admet-1317	277	18	master	master	NOUN
admet-1317	277	19	structure	structure	NOUN
admet-1317	277	20	(	(	PUNCT
admet-1317	277	21	pdms	pdms	NOUN
admet-1317	277	22	mould	mould	NOUN
admet-1317	277	23	)	)	PUNCT
admet-1317	277	24	,	,	PUNCT
admet-1317	277	25	which	which	PRON
admet-1317	277	26	is	be	AUX
admet-1317	277	27	500	500	NUM
admet-1317	277	28	μm	μm	NOUN
admet-1317	277	29	needle	needle	NOUN
admet-1317	277	30	length	length	NOUN
admet-1317	277	31	.	.	PUNCT
admet-1317	278	1	this	this	PRON
admet-1317	278	2	can	can	AUX
admet-1317	278	3	occur	occur	VERB
admet-1317	278	4	due	due	ADP
admet-1317	278	5	to	to	ADP
admet-1317	278	6	the	the	DET
admet-1317	278	7	difference	difference	NOUN
admet-1317	278	8	in	in	ADP
admet-1317	278	9	polymer	polymer	NOUN
admet-1317	278	10	filling	filling	NOUN
admet-1317	278	11	capability	capability	NOUN
admet-1317	278	12	into	into	ADP
admet-1317	278	13	the	the	DET
admet-1317	278	14	mould	mould	NOUN
admet-1317	278	15	,	,	PUNCT
admet-1317	278	16	which	which	PRON
admet-1317	278	17	is	be	AUX
admet-1317	278	18	based	base	VERB
admet-1317	278	19	on	on	ADP
admet-1317	278	20	the	the	DET
admet-1317	278	21	polymer	polymer	NOUN
admet-1317	278	22	viscosity	viscosity	NOUN
admet-1317	278	23	and	and	CCONJ
admet-1317	278	24	the	the	DET
admet-1317	278	25	shrinkage	shrinkage	NOUN
admet-1317	278	26	of	of	ADP
admet-1317	278	27	polymeric	polymeric	ADJ
admet-1317	278	28	solution	solution	NOUN
admet-1317	278	29	during	during	ADP
admet-1317	278	30	drying	dry	VERB
admet-1317	278	31	[	[	PUNCT
admet-1317	278	32	45	45	NUM
admet-1317	278	33	]	]	PUNCT
admet-1317	278	34	.	.	PUNCT
admet-1317	279	1	it	it	PRON
admet-1317	279	2	is	be	AUX
admet-1317	279	3	anticipated	anticipate	VERB
admet-1317	279	4	that	that	SCONJ
admet-1317	279	5	this	this	DET
admet-1317	279	6	reduction	reduction	NOUN
admet-1317	279	7	in	in	ADP
admet-1317	279	8	the	the	DET
admet-1317	279	9	length	length	NOUN
admet-1317	279	10	of	of	ADP
admet-1317	279	11	mns	mns	PROPN
admet-1317	279	12	does	do	AUX
admet-1317	279	13	not	not	PART
admet-1317	279	14	greatly	greatly	ADV
admet-1317	279	15	influence	influence	VERB
admet-1317	279	16	the	the	DET
admet-1317	279	17	transdermal	transdermal	ADJ
admet-1317	279	18	delivery	delivery	NOUN
admet-1317	279	19	of	of	ADP
admet-1317	279	20	lt-4	lt-4	NOUN
admet-1317	279	21	sodium	sodium	NOUN
admet-1317	279	22	since	since	SCONJ
admet-1317	279	23	they	they	PRON
admet-1317	279	24	showed	show	VERB
admet-1317	279	25	the	the	DET
admet-1317	279	26	excellent	excellent	ADJ
admet-1317	279	27	formation	formation	NOUN
admet-1317	279	28	of	of	ADP
admet-1317	279	29	microchannels	microchannel	NOUN
admet-1317	279	30	through	through	ADP
admet-1317	279	31	the	the	DET
admet-1317	279	32	different	different	ADJ
admet-1317	279	33	skin	skin	NOUN
admet-1317	279	34	layers	layer	NOUN
admet-1317	279	35	,	,	PUNCT
admet-1317	279	36	including	include	VERB
admet-1317	279	37	the	the	DET
admet-1317	279	38	dermis	dermis	NOUN
admet-1317	279	39	where	where	SCONJ
admet-1317	279	40	the	the	DET
admet-1317	279	41	drug	drug	NOUN
admet-1317	279	42	can	can	AUX
admet-1317	279	43	be	be	AUX
admet-1317	279	44	systemically	systemically	ADV
admet-1317	279	45	absorbed	absorb	VERB
admet-1317	279	46	.	.	PUNCT
admet-1317	280	1	figure	figure	NOUN
admet-1317	280	2	8	8	NUM
admet-1317	280	3	.	.	PUNCT
admet-1317	281	1	sem	sem	NOUN
admet-1317	281	2	images	image	NOUN
admet-1317	281	3	of	of	ADP
admet-1317	281	4	ha	ha	INTJ
admet-1317	281	5	mn	mn	PROPN
admet-1317	281	6	array	array	PROPN
admet-1317	281	7	f11	f11	PROPN
admet-1317	281	8	,	,	PUNCT
admet-1317	281	9	where	where	SCONJ
admet-1317	281	10	:	:	PUNCT
admet-1317	281	11	(	(	PUNCT
admet-1317	281	12	a	a	X
admet-1317	281	13	)	)	PUNCT
admet-1317	281	14	top	top	ADJ
admet-1317	281	15	view	view	NOUN
admet-1317	281	16	of	of	ADP
admet-1317	281	17	mn	mn	PROPN
admet-1317	281	18	array	array	NOUN
admet-1317	281	19	at	at	ADP
admet-1317	281	20	a	a	DET
admet-1317	281	21	magnification	magnification	NOUN
admet-1317	281	22	of	of	ADP
admet-1317	281	23	200x	200x	NUM
admet-1317	281	24	,	,	PUNCT
admet-1317	281	25	(	(	PUNCT
admet-1317	281	26	b	b	X
admet-1317	281	27	)	)	PUNCT
admet-1317	281	28	a	a	DET
admet-1317	281	29	single	single	ADJ
admet-1317	281	30	array	array	NOUN
admet-1317	281	31	of	of	ADP
admet-1317	281	32	pyramidal	pyramidal	NOUN
admet-1317	281	33	-	-	PUNCT
admet-1317	281	34	shaped	shape	VERB
admet-1317	281	35	mns	mns	PROPN
admet-1317	281	36	shows	show	VERB
admet-1317	281	37	the	the	DET
admet-1317	281	38	distance	distance	NOUN
admet-1317	281	39	between	between	ADP
admet-1317	281	40	two	two	NUM
admet-1317	281	41	needles	needle	NOUN
admet-1317	281	42	at	at	ADP
admet-1317	281	43	a	a	DET
admet-1317	281	44	magnification	magnification	NOUN
admet-1317	281	45	of	of	ADP
admet-1317	281	46	100x	100x	NUM
admet-1317	281	47	,	,	PUNCT
admet-1317	281	48	(	(	PUNCT
admet-1317	281	49	c	c	X
admet-1317	281	50	)	)	PUNCT
admet-1317	281	51	top	top	ADJ
admet-1317	281	52	view	view	NOUN
admet-1317	281	53	of	of	ADP
admet-1317	281	54	a	a	DET
admet-1317	281	55	single	single	ADJ
admet-1317	281	56	needle	needle	NOUN
admet-1317	281	57	in	in	ADP
admet-1317	281	58	the	the	DET
admet-1317	281	59	array	array	NOUN
admet-1317	281	60	showing	show	VERB
admet-1317	281	61	the	the	DET
admet-1317	281	62	base	base	NOUN
admet-1317	281	63	width	width	NOUN
admet-1317	281	64	at	at	ADP
admet-1317	281	65	a	a	DET
admet-1317	281	66	magnification	magnification	NOUN
admet-1317	281	67	of	of	ADP
admet-1317	281	68	300x	300x	NUM
admet-1317	281	69	,	,	PUNCT
admet-1317	281	70	and	and	CCONJ
admet-1317	281	71	(	(	PUNCT
admet-1317	281	72	d	d	X
admet-1317	281	73	)	)	PUNCT
admet-1317	281	74	lateral	lateral	ADJ
admet-1317	281	75	view	view	NOUN
admet-1317	281	76	of	of	ADP
admet-1317	281	77	mns	mns	PROPN
admet-1317	281	78	showing	show	VERB
admet-1317	281	79	the	the	DET
admet-1317	281	80	needle	needle	NOUN
admet-1317	281	81	length	length	NOUN
admet-1317	281	82	at	at	ADP
admet-1317	281	83	a	a	DET
admet-1317	281	84	magnification	magnification	NOUN
admet-1317	281	85	of	of	ADP
admet-1317	281	86	200x	200x	NUM
admet-1317	281	87	.	.	PUNCT
admet-1317	282	1	ex	ex	PRON
admet-1317	282	2	vivo	vivo	ADJ
admet-1317	282	3	permeation	permeation	NOUN
admet-1317	282	4	study	study	VERB
admet-1317	282	5	the	the	DET
admet-1317	282	6	transdermal	transdermal	ADJ
admet-1317	282	7	delivery	delivery	NOUN
admet-1317	282	8	of	of	ADP
admet-1317	282	9	lt-4	lt-4	NOUN
admet-1317	282	10	sodium	sodium	NOUN
admet-1317	282	11	is	be	AUX
admet-1317	282	12	limited	limit	VERB
admet-1317	282	13	due	due	ADP
admet-1317	282	14	to	to	ADP
admet-1317	282	15	its	its	PRON
admet-1317	282	16	low	low	ADJ
admet-1317	282	17	permeability	permeability	NOUN
admet-1317	282	18	characteristics	characteristic	NOUN
admet-1317	282	19	through	through	ADP
admet-1317	282	20	the	the	DET
admet-1317	282	21	stratum	stratum	NOUN
admet-1317	282	22	corneum	corneum	NOUN
admet-1317	282	23	layer	layer	NOUN
admet-1317	282	24	.	.	PUNCT
admet-1317	283	1	mns	mns	PROPN
admet-1317	283	2	may	may	AUX
admet-1317	283	3	enable	enable	VERB
admet-1317	283	4	lt-4	lt-4	ADJ
admet-1317	283	5	sodium	sodium	NOUN
admet-1317	283	6	delivery	delivery	NOUN
admet-1317	283	7	through	through	ADP
admet-1317	283	8	the	the	DET
admet-1317	283	9	skin	skin	NOUN
admet-1317	283	10	by	by	ADP
admet-1317	283	11	physically	physically	ADV
admet-1317	283	12	disrupting	disrupt	VERB
admet-1317	283	13	the	the	DET
admet-1317	283	14	stratum	stratum	NOUN
admet-1317	283	15	corneum	corneum	NOUN
admet-1317	283	16	barrier	barrier	NOUN
admet-1317	283	17	and	and	CCONJ
admet-1317	283	18	transferring	transfer	VERB
admet-1317	283	19	molecules	molecule	NOUN
admet-1317	283	20	through	through	ADP
admet-1317	283	21	the	the	DET
admet-1317	283	22	micro	micro	NOUN
admet-1317	283	23	-	-	NOUN
admet-1317	283	24	channels	channel	NOUN
admet-1317	283	25	into	into	ADP
admet-1317	283	26	the	the	DET
admet-1317	283	27	dermis	dermis	NOUN
admet-1317	283	28	microcirculation	microcirculation	NOUN
admet-1317	283	29	.	.	PUNCT
admet-1317	284	1	therefore	therefore	ADV
admet-1317	284	2	,	,	PUNCT
admet-1317	284	3	to	to	PART
admet-1317	284	4	investigate	investigate	VERB
admet-1317	284	5	the	the	DET
admet-1317	284	6	influence	influence	NOUN
admet-1317	284	7	of	of	ADP
admet-1317	284	8	mns	mns	PROPN
admet-1317	284	9	in	in	ADP
admet-1317	284	10	enhancing	enhance	VERB
admet-1317	284	11	transdermal	transdermal	ADJ
admet-1317	284	12	delivery	delivery	NOUN
admet-1317	284	13	of	of	ADP
admet-1317	284	14	lt-4	lt-4	NOUN
admet-1317	284	15	sodium	sodium	NOUN
admet-1317	284	16	through	through	ADP
admet-1317	284	17	the	the	DET
admet-1317	284	18	skin	skin	NOUN
admet-1317	284	19	,	,	PUNCT
admet-1317	284	20	an	an	DET
admet-1317	284	21	ex	ex	X
admet-1317	284	22	vivo	vivo	NOUN
admet-1317	284	23	permeation	permeation	NOUN
admet-1317	284	24	study	study	NOUN
admet-1317	284	25	using	use	VERB
admet-1317	284	26	human	human	ADJ
admet-1317	284	27	skin	skin	NOUN
admet-1317	284	28	was	be	AUX
admet-1317	284	29	carried	carry	VERB
admet-1317	284	30	out	out	ADP
admet-1317	284	31	.	.	PUNCT
admet-1317	285	1	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	VERB
admet-1317	286	1	r.f	r.f	PROPN
admet-1317	286	2	.	.	PROPN
admet-1317	286	3	ghazi	ghazi	PROPN
admet-1317	286	4	and	and	CCONJ
admet-1317	286	5	m.h	m.h	PROPN
admet-1317	286	6	.	.	PROPN
admet-1317	286	7	al	al	PROPN
admet-1317	286	8	-	-	PUNCT
admet-1317	286	9	mayahy	mayahy	PROPN
admet-1317	286	10	admet	admet	PROPN
admet-1317	286	11	&	&	CCONJ
admet-1317	286	12	dmpk	dmpk	PROPN
admet-1317	286	13	10(3	10(3	NUM
admet-1317	286	14	)	)	PUNCT
admet-1317	286	15	(	(	PUNCT
admet-1317	286	16	2022	2022	NUM
admet-1317	286	17	)	)	PUNCT
admet-1317	286	18	213	213	NUM
admet-1317	286	19	-	-	SYM
admet-1317	286	20	230	230	NUM
admet-1317	286	21	226	226	NUM
admet-1317	286	22	ha	ha	INTJ
admet-1317	286	23	mn	mn	PROPN
admet-1317	286	24	array	array	PROPN
admet-1317	286	25	formula	formula	NOUN
admet-1317	286	26	f11	f11	PROPN
admet-1317	286	27	was	be	AUX
admet-1317	286	28	used	use	VERB
admet-1317	286	29	in	in	ADP
admet-1317	286	30	this	this	DET
admet-1317	286	31	permeation	permeation	NOUN
admet-1317	286	32	study	study	NOUN
admet-1317	286	33	since	since	SCONJ
admet-1317	286	34	it	it	PRON
admet-1317	286	35	is	be	AUX
admet-1317	286	36	regarded	regard	VERB
admet-1317	286	37	as	as	ADP
admet-1317	286	38	the	the	DET
admet-1317	286	39	optimum	optimum	ADJ
admet-1317	286	40	formula	formula	NOUN
admet-1317	286	41	,	,	PUNCT
admet-1317	286	42	as	as	SCONJ
admet-1317	286	43	shown	show	VERB
admet-1317	286	44	previously	previously	ADV
admet-1317	286	45	.	.	PUNCT
admet-1317	287	1	in	in	ADP
admet-1317	287	2	addition	addition	NOUN
admet-1317	287	3	,	,	PUNCT
admet-1317	287	4	to	to	ADP
admet-1317	287	5	the	the	DET
admet-1317	287	6	use	use	NOUN
admet-1317	287	7	of	of	ADP
admet-1317	287	8	f11	f11	PROPN
admet-1317	287	9	mn	mn	PROPN
admet-1317	287	10	arrays	array	VERB
admet-1317	287	11	in	in	ADP
admet-1317	287	12	the	the	DET
admet-1317	287	13	permeation	permeation	NOUN
admet-1317	287	14	study	study	NOUN
admet-1317	287	15	,	,	PUNCT
admet-1317	287	16	control	control	NOUN
admet-1317	287	17	formulas	formula	NOUN
admet-1317	287	18	of	of	ADP
admet-1317	287	19	lt-4	lt-4	NOUN
admet-1317	287	20	sodium	sodium	NOUN
admet-1317	287	21	as	as	ADP
admet-1317	287	22	an	an	DET
admet-1317	287	23	aqueous	aqueous	ADJ
admet-1317	287	24	solution	solution	NOUN
admet-1317	287	25	and	and	CCONJ
admet-1317	287	26	as	as	ADP
admet-1317	287	27	a	a	DET
admet-1317	287	28	polymeric	polymeric	ADJ
admet-1317	287	29	film	film	NOUN
admet-1317	287	30	without	without	ADP
admet-1317	287	31	needles	needle	NOUN
admet-1317	287	32	(	(	PUNCT
admet-1317	287	33	needle	needle	NOUN
admet-1317	287	34	-	-	PUNCT
admet-1317	287	35	free	free	ADJ
admet-1317	287	36	)	)	PUNCT
admet-1317	287	37	were	be	AUX
admet-1317	287	38	utilized	utilize	VERB
admet-1317	287	39	for	for	ADP
admet-1317	287	40	comparison	comparison	NOUN
admet-1317	287	41	purposes	purpose	NOUN
admet-1317	287	42	.	.	PUNCT
admet-1317	288	1	the	the	DET
admet-1317	288	2	cumulative	cumulative	ADJ
admet-1317	288	3	amount	amount	NOUN
admet-1317	288	4	of	of	ADP
admet-1317	288	5	lt-4	lt-4	NOUN
admet-1317	288	6	sodium	sodium	NOUN
admet-1317	288	7	permeated	permeate	VERB
admet-1317	288	8	from	from	ADP
admet-1317	288	9	mn	mn	PROPN
admet-1317	288	10	array	array	PROPN
admet-1317	288	11	f11	f11	PROPN
admet-1317	288	12	,	,	PUNCT
admet-1317	288	13	drug	drug	NOUN
admet-1317	288	14	solution	solution	NOUN
admet-1317	288	15	and	and	CCONJ
admet-1317	288	16	the	the	DET
admet-1317	288	17	polymeric	polymeric	ADJ
admet-1317	288	18	film	film	NOUN
admet-1317	288	19	is	be	AUX
admet-1317	288	20	demonstrated	demonstrate	VERB
admet-1317	288	21	in	in	ADP
admet-1317	288	22	figure	figure	NOUN
admet-1317	288	23	9	9	NUM
admet-1317	288	24	.	.	PUNCT
admet-1317	289	1	as	as	SCONJ
admet-1317	289	2	can	can	AUX
admet-1317	289	3	be	be	AUX
admet-1317	289	4	observed	observe	VERB
admet-1317	289	5	from	from	ADP
admet-1317	289	6	the	the	DET
admet-1317	289	7	graph	graph	NOUN
admet-1317	289	8	,	,	PUNCT
admet-1317	289	9	the	the	DET
admet-1317	289	10	microneedle	microneedle	PROPN
admet-1317	289	11	array	array	PROPN
admet-1317	289	12	f11	f11	PROPN
admet-1317	289	13	has	have	VERB
admet-1317	289	14	significantly	significantly	ADV
admet-1317	289	15	(	(	PUNCT
admet-1317	289	16	p	p	NOUN
admet-1317	289	17	≤	≤	NUM
admet-1317	289	18	0.05	0.05	NUM
admet-1317	289	19	)	)	PUNCT
admet-1317	289	20	increased	increase	VERB
admet-1317	289	21	lt-4	lt-4	NOUN
admet-1317	289	22	sodium	sodium	NOUN
admet-1317	289	23	permeation	permeation	NOUN
admet-1317	289	24	through	through	ADP
admet-1317	289	25	the	the	DET
admet-1317	289	26	skin	skin	NOUN
admet-1317	289	27	(	(	PUNCT
admet-1317	289	28	cumulative	cumulative	ADJ
admet-1317	289	29	permeated	permeate	VERB
admet-1317	289	30	amount	amount	NOUN
admet-1317	289	31	of	of	ADP
admet-1317	289	32	32	32	NUM
admet-1317	289	33	±	±	NUM
admet-1317	289	34	2	2	NUM
admet-1317	289	35	µg	µg	NOUN
admet-1317	289	36	/	/	SYM
admet-1317	289	37	cm²	cm²	PROPN
admet-1317	289	38	)	)	PUNCT
admet-1317	289	39	in	in	ADP
admet-1317	289	40	comparison	comparison	NOUN
admet-1317	289	41	to	to	ADP
admet-1317	289	42	solution	solution	NOUN
admet-1317	289	43	control	control	NOUN
admet-1317	289	44	(	(	PUNCT
admet-1317	289	45	cumulative	cumulative	ADJ
admet-1317	289	46	permeated	permeate	VERB
admet-1317	289	47	amount	amount	NOUN
admet-1317	289	48	of	of	ADP
admet-1317	289	49	0.7	0.7	NUM
admet-1317	289	50	±	±	NUM
admet-1317	289	51	0.07	0.07	NUM
admet-1317	289	52	µg	µg	NOUN
admet-1317	289	53	/	/	SYM
admet-1317	289	54	cm²	cm²	PROPN
admet-1317	289	55	)	)	PUNCT
admet-1317	289	56	and	and	CCONJ
admet-1317	289	57	the	the	DET
admet-1317	289	58	polymeric	polymeric	ADJ
admet-1317	289	59	film	film	NOUN
admet-1317	289	60	(	(	PUNCT
admet-1317	289	61	0.1	0.1	NUM
admet-1317	289	62	±	±	NUM
admet-1317	289	63	0.02	0.02	NUM
admet-1317	289	64	µg	µg	NOUN
admet-1317	289	65	/	/	SYM
admet-1317	289	66	cm²	cm²	PROPN
admet-1317	289	67	)	)	PUNCT
admet-1317	289	68	over	over	ADP
admet-1317	289	69	the	the	DET
admet-1317	289	70	period	period	NOUN
admet-1317	289	71	of	of	ADP
admet-1317	289	72	7	7	NUM
admet-1317	289	73	hours	hour	NOUN
admet-1317	289	74	.	.	PUNCT
admet-1317	290	1	the	the	DET
admet-1317	290	2	mns	mns	PROPN
admet-1317	290	3	arrays	array	NOUN
admet-1317	290	4	have	have	AUX
admet-1317	290	5	delivered	deliver	VERB
admet-1317	290	6	64	64	NUM
admet-1317	290	7	%	%	NOUN
admet-1317	290	8	±	±	NUM
admet-1317	290	9	4	4	NUM
admet-1317	290	10	of	of	ADP
admet-1317	290	11	their	their	PRON
admet-1317	290	12	loading	loading	NOUN
admet-1317	290	13	dose	dose	VERB
admet-1317	290	14	over	over	ADP
admet-1317	290	15	7	7	NUM
admet-1317	290	16	hours	hour	NOUN
admet-1317	290	17	period	period	NOUN
admet-1317	290	18	,	,	PUNCT
admet-1317	290	19	whereas	whereas	SCONJ
admet-1317	290	20	the	the	DET
admet-1317	290	21	control	control	NOUN
admet-1317	290	22	preparations	preparation	NOUN
admet-1317	290	23	of	of	ADP
admet-1317	290	24	aqueous	aqueous	ADJ
admet-1317	290	25	solution	solution	NOUN
admet-1317	290	26	and	and	CCONJ
admet-1317	290	27	polymeric	polymeric	ADJ
admet-1317	290	28	film	film	NOUN
admet-1317	290	29	were	be	AUX
admet-1317	290	30	only	only	ADV
admet-1317	290	31	able	able	ADJ
admet-1317	290	32	to	to	PART
admet-1317	290	33	deliver	deliver	VERB
admet-1317	290	34	1.4	1.4	NUM
admet-1317	290	35	%	%	NOUN
admet-1317	290	36	±	±	NUM
admet-1317	290	37	0.14	0.14	NUM
admet-1317	290	38	and	and	CCONJ
admet-1317	291	1	0.2	0.2	NUM
admet-1317	291	2	%	%	NOUN
admet-1317	292	1	±	±	NUM
admet-1317	292	2	0.04	0.04	NUM
admet-1317	292	3	of	of	ADP
admet-1317	292	4	total	total	ADJ
admet-1317	292	5	loading	loading	NOUN
admet-1317	292	6	dose	dose	NOUN
admet-1317	292	7	,	,	PUNCT
admet-1317	292	8	respectively	respectively	ADV
admet-1317	292	9	,	,	PUNCT
admet-1317	292	10	during	during	ADP
admet-1317	292	11	the	the	DET
admet-1317	292	12	same	same	ADJ
admet-1317	292	13	period	period	NOUN
admet-1317	292	14	.	.	PUNCT
admet-1317	293	1	this	this	PRON
admet-1317	293	2	represents	represent	VERB
admet-1317	293	3	an	an	DET
admet-1317	293	4	approximately	approximately	ADV
admet-1317	293	5	46	46	NUM
admet-1317	293	6	-	-	SYM
admet-1317	293	7	320	320	NUM
admet-1317	293	8	fold	fold	NOUN
admet-1317	293	9	increase	increase	NOUN
admet-1317	293	10	in	in	ADP
admet-1317	293	11	delivery	delivery	NOUN
admet-1317	293	12	of	of	ADP
admet-1317	293	13	lt-4	lt-4	NOUN
admet-1317	293	14	sodium	sodium	NOUN
admet-1317	293	15	than	than	SCONJ
admet-1317	293	16	that	that	PRON
admet-1317	293	17	was	be	AUX
admet-1317	293	18	achieved	achieve	VERB
admet-1317	293	19	with	with	ADP
admet-1317	293	20	the	the	DET
admet-1317	293	21	control	control	NOUN
admet-1317	293	22	preparations	preparation	NOUN
admet-1317	293	23	(	(	PUNCT
admet-1317	293	24	aqueous	aqueous	ADJ
admet-1317	293	25	solution	solution	NOUN
admet-1317	293	26	and	and	CCONJ
admet-1317	293	27	polymeric	polymeric	ADJ
admet-1317	293	28	film	film	NOUN
admet-1317	293	29	,	,	PUNCT
admet-1317	293	30	respectively	respectively	ADV
admet-1317	293	31	)	)	PUNCT
admet-1317	293	32	.	.	PUNCT
admet-1317	294	1	moreover	moreover	ADV
admet-1317	294	2	,	,	PUNCT
admet-1317	294	3	as	as	SCONJ
admet-1317	294	4	the	the	DET
admet-1317	294	5	drug	drug	NOUN
admet-1317	294	6	was	be	AUX
admet-1317	294	7	encapsulated	encapsulate	VERB
admet-1317	294	8	within	within	ADP
admet-1317	294	9	mn	mn	PROPN
admet-1317	294	10	arrays	array	VERB
admet-1317	294	11	,	,	PUNCT
admet-1317	294	12	the	the	DET
admet-1317	294	13	lag	lag	NOUN
admet-1317	294	14	time	time	NOUN
admet-1317	294	15	was	be	AUX
admet-1317	294	16	less	less	ADJ
admet-1317	294	17	since	since	SCONJ
admet-1317	294	18	the	the	DET
admet-1317	294	19	drug	drug	NOUN
admet-1317	294	20	began	begin	VERB
admet-1317	294	21	to	to	PART
admet-1317	294	22	diffuse	diffuse	VERB
admet-1317	294	23	quickly	quickly	ADV
admet-1317	294	24	upon	upon	SCONJ
admet-1317	294	25	application	application	NOUN
admet-1317	294	26	of	of	ADP
admet-1317	294	27	mns	mns	PROPN
admet-1317	294	28	.	.	PUNCT
admet-1317	295	1	in	in	ADP
admet-1317	295	2	this	this	DET
admet-1317	295	3	study	study	NOUN
admet-1317	295	4	,	,	PUNCT
admet-1317	295	5	the	the	DET
admet-1317	295	6	ha	ha	INTJ
admet-1317	295	7	mns	mns	PROPN
admet-1317	295	8	were	be	AUX
admet-1317	295	9	started	start	VERB
admet-1317	295	10	to	to	PART
admet-1317	295	11	dissolve	dissolve	VERB
admet-1317	295	12	within	within	ADP
admet-1317	295	13	5	5	NUM
admet-1317	295	14	minutes	minute	NOUN
admet-1317	295	15	of	of	ADP
admet-1317	295	16	application	application	NOUN
admet-1317	295	17	into	into	ADP
admet-1317	295	18	the	the	DET
admet-1317	295	19	skin	skin	NOUN
admet-1317	295	20	,	,	PUNCT
admet-1317	295	21	supporting	support	VERB
admet-1317	295	22	the	the	DET
admet-1317	295	23	shortening	shortening	NOUN
admet-1317	295	24	in	in	ADP
admet-1317	295	25	lag	lag	NOUN
admet-1317	295	26	time	time	NOUN
admet-1317	295	27	.	.	PUNCT
admet-1317	296	1	the	the	DET
admet-1317	296	2	lag	lag	NOUN
admet-1317	296	3	time	time	NOUN
admet-1317	296	4	for	for	ADP
admet-1317	296	5	the	the	DET
admet-1317	296	6	mn	mn	PROPN
admet-1317	296	7	arrays	array	NOUN
admet-1317	296	8	was	be	AUX
admet-1317	296	9	only	only	ADV
admet-1317	296	10	10	10	NUM
admet-1317	296	11	minutes	minute	NOUN
admet-1317	296	12	,	,	PUNCT
admet-1317	296	13	while	while	SCONJ
admet-1317	296	14	the	the	DET
admet-1317	296	15	drug	drug	NOUN
admet-1317	296	16	solution	solution	NOUN
admet-1317	296	17	(	(	PUNCT
admet-1317	296	18	control	control	NOUN
admet-1317	296	19	)	)	PUNCT
admet-1317	296	20	lag	lag	NOUN
admet-1317	296	21	time	time	NOUN
admet-1317	296	22	was	be	AUX
admet-1317	296	23	44	44	NUM
admet-1317	296	24	minutes	minute	NOUN
admet-1317	296	25	and	and	CCONJ
admet-1317	296	26	the	the	DET
admet-1317	296	27	polymeric	polymeric	ADJ
admet-1317	296	28	film	film	NOUN
admet-1317	296	29	lag	lag	NOUN
admet-1317	296	30	time	time	NOUN
admet-1317	296	31	was	be	AUX
admet-1317	296	32	120	120	NUM
admet-1317	296	33	minutes	minute	NOUN
admet-1317	296	34	.	.	PUNCT
admet-1317	297	1	this	this	DET
admet-1317	297	2	enhancement	enhancement	NOUN
admet-1317	297	3	of	of	ADP
admet-1317	297	4	lt-4	lt-4	NOUN
admet-1317	297	5	sodium	sodium	NOUN
admet-1317	297	6	delivery	delivery	NOUN
admet-1317	297	7	is	be	AUX
admet-1317	297	8	related	relate	VERB
admet-1317	297	9	to	to	ADP
admet-1317	297	10	the	the	DET
admet-1317	297	11	ability	ability	NOUN
admet-1317	297	12	of	of	ADP
admet-1317	297	13	mns	mns	PROPN
admet-1317	297	14	to	to	PART
admet-1317	297	15	bypass	bypass	VERB
admet-1317	297	16	the	the	DET
admet-1317	297	17	stratum	stratum	NOUN
admet-1317	297	18	corneum	corneum	NOUN
admet-1317	297	19	barrier	barrier	NOUN
admet-1317	297	20	by	by	ADP
admet-1317	297	21	creating	create	VERB
admet-1317	297	22	microchannels	microchannel	NOUN
admet-1317	297	23	through	through	ADP
admet-1317	297	24	the	the	DET
admet-1317	297	25	skin	skin	NOUN
admet-1317	297	26	to	to	PART
admet-1317	297	27	facilitate	facilitate	VERB
admet-1317	297	28	drug	drug	NOUN
admet-1317	297	29	permeation	permeation	NOUN
admet-1317	297	30	.	.	PUNCT
admet-1317	298	1	in	in	ADP
admet-1317	298	2	addition	addition	NOUN
admet-1317	298	3	,	,	PUNCT
admet-1317	298	4	the	the	DET
admet-1317	298	5	hydration	hydration	NOUN
admet-1317	298	6	of	of	ADP
admet-1317	298	7	the	the	DET
admet-1317	298	8	drug	drug	NOUN
admet-1317	298	9	reservoir	reservoir	NOUN
admet-1317	298	10	in	in	ADP
admet-1317	298	11	the	the	DET
admet-1317	298	12	polymer	polymer	NOUN
admet-1317	298	13	matrix	matrix	NOUN
admet-1317	298	14	is	be	AUX
admet-1317	298	15	enhanced	enhance	VERB
admet-1317	298	16	by	by	ADP
admet-1317	298	17	the	the	DET
admet-1317	298	18	fluid	fluid	NOUN
admet-1317	298	19	withdrawn	withdraw	VERB
admet-1317	298	20	from	from	ADP
admet-1317	298	21	the	the	DET
admet-1317	298	22	skin	skin	NOUN
admet-1317	298	23	via	via	ADP
admet-1317	298	24	the	the	DET
admet-1317	298	25	microchannels	microchannel	NOUN
admet-1317	298	26	leading	lead	VERB
admet-1317	298	27	to	to	ADP
admet-1317	298	28	an	an	DET
admet-1317	298	29	improvement	improvement	NOUN
admet-1317	298	30	in	in	ADP
admet-1317	298	31	drug	drug	NOUN
admet-1317	298	32	diffusion	diffusion	NOUN
admet-1317	298	33	[	[	X
admet-1317	298	34	40	40	NUM
admet-1317	298	35	]	]	PUNCT
admet-1317	298	36	.	.	PUNCT
admet-1317	299	1	the	the	DET
admet-1317	299	2	results	result	NOUN
admet-1317	299	3	obtained	obtain	VERB
admet-1317	299	4	from	from	ADP
admet-1317	299	5	this	this	DET
admet-1317	299	6	permeation	permeation	NOUN
admet-1317	299	7	study	study	NOUN
admet-1317	299	8	suggest	suggest	VERB
admet-1317	299	9	the	the	DET
admet-1317	299	10	successful	successful	ADJ
admet-1317	299	11	application	application	NOUN
admet-1317	299	12	of	of	ADP
admet-1317	299	13	ha	ha	INTJ
admet-1317	299	14	mn	mn	PROPN
admet-1317	299	15	arrays	array	VERB
admet-1317	299	16	in	in	ADP
admet-1317	299	17	the	the	DET
admet-1317	299	18	delivery	delivery	NOUN
admet-1317	299	19	of	of	ADP
admet-1317	299	20	lt-4	lt-4	NOUN
admet-1317	299	21	sodium	sodium	NOUN
admet-1317	299	22	.	.	PUNCT
admet-1317	300	1	this	this	PRON
admet-1317	300	2	can	can	AUX
admet-1317	300	3	be	be	AUX
admet-1317	300	4	considered	consider	VERB
admet-1317	300	5	a	a	DET
admet-1317	300	6	promising	promising	ADJ
admet-1317	300	7	approach	approach	NOUN
admet-1317	300	8	when	when	SCONJ
admet-1317	300	9	used	use	VERB
admet-1317	300	10	in	in	ADP
admet-1317	300	11	humans	human	NOUN
admet-1317	300	12	since	since	SCONJ
admet-1317	300	13	it	it	PRON
admet-1317	300	14	may	may	AUX
admet-1317	300	15	improve	improve	VERB
admet-1317	300	16	lt-4	lt-4	NOUN
admet-1317	300	17	sodium	sodium	NOUN
admet-1317	300	18	bioavailability	bioavailability	NOUN
admet-1317	300	19	.	.	PUNCT
admet-1317	301	1	figure	figure	NOUN
admet-1317	301	2	9	9	NUM
admet-1317	301	3	.	.	PUNCT
admet-1317	302	1	the	the	DET
admet-1317	302	2	cumulative	cumulative	ADJ
admet-1317	302	3	amount	amount	NOUN
admet-1317	302	4	of	of	ADP
admet-1317	302	5	lt-4	lt-4	NOUN
admet-1317	302	6	sodium	sodium	NOUN
admet-1317	302	7	permeated	permeate	VERB
admet-1317	302	8	across	across	ADP
admet-1317	302	9	human	human	ADJ
admet-1317	302	10	skin	skin	NOUN
admet-1317	302	11	in	in	ADP
admet-1317	302	12	µg	µg	ADV
admet-1317	302	13	/	/	SYM
admet-1317	302	14	cm²	cm²	NOUN
admet-1317	302	15	from	from	ADP
admet-1317	302	16	ha	ha	INTJ
admet-1317	302	17	mn	mn	PROPN
admet-1317	302	18	arrays	array	VERB
admet-1317	302	19	f11	f11	PROPN
admet-1317	302	20	in	in	ADP
admet-1317	302	21	comparison	comparison	NOUN
admet-1317	302	22	to	to	PART
admet-1317	302	23	control	control	VERB
admet-1317	302	24	preparations	preparation	NOUN
admet-1317	302	25	(	(	PUNCT
admet-1317	302	26	aqueous	aqueous	ADJ
admet-1317	302	27	drug	drug	NOUN
admet-1317	302	28	solution	solution	NOUN
admet-1317	302	29	and	and	CCONJ
admet-1317	302	30	polymeric	polymeric	ADJ
admet-1317	302	31	film	film	NOUN
admet-1317	302	32	)	)	PUNCT
admet-1317	302	33	.	.	PUNCT
admet-1317	303	1	data	datum	NOUN
admet-1317	303	2	is	be	AUX
admet-1317	303	3	presented	present	VERB
admet-1317	303	4	as	as	ADP
admet-1317	303	5	the	the	DET
admet-1317	303	6	mean	mean	ADJ
admet-1317	303	7	±	±	PROPN
admet-1317	303	8	sd	sd	NOUN
admet-1317	303	9	(	(	PUNCT
admet-1317	303	10	n	n	NOUN
admet-1317	303	11	=	=	SYM
admet-1317	303	12	6	6	NUM
admet-1317	303	13	)	)	PUNCT
admet-1317	303	14	.	.	PUNCT
admet-1317	304	1	admet	admet	PROPN
admet-1317	304	2	&	&	CCONJ
admet-1317	304	3	dmpk	dmpk	PROPN
admet-1317	304	4	10(3	10(3	NUM
admet-1317	304	5	)	)	PUNCT
admet-1317	304	6	(	(	PUNCT
admet-1317	304	7	2022	2022	NUM
admet-1317	304	8	)	)	PUNCT
admet-1317	304	9	213	213	NUM
admet-1317	304	10	-	-	SYM
admet-1317	304	11	230	230	NUM
admet-1317	304	12	transdermal	transdermal	ADJ
admet-1317	304	13	delivery	delivery	NOUN
admet-1317	304	14	of	of	ADP
admet-1317	304	15	levothyroxine	levothyroxine	NOUN
admet-1317	304	16	via	via	ADP
admet-1317	304	17	dissolving	dissolve	VERB
admet-1317	304	18	microneedles	microneedle	NOUN
admet-1317	304	19	doi	doi	PROPN
admet-1317	304	20	:	:	PUNCT
admet-1317	304	21	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	NUM
admet-1317	304	22	227	227	NUM
admet-1317	304	23	skin	skin	NOUN
admet-1317	304	24	irritation	irritation	NOUN
admet-1317	304	25	test	test	NOUN
admet-1317	304	26	.	.	PUNCT
admet-1317	305	1	in	in	ADP
admet-1317	305	2	the	the	DET
admet-1317	305	3	skin	skin	NOUN
admet-1317	305	4	irritation	irritation	NOUN
admet-1317	305	5	test	test	NOUN
admet-1317	305	6	,	,	PUNCT
admet-1317	305	7	the	the	DET
admet-1317	305	8	scores	score	NOUN
admet-1317	305	9	for	for	ADP
admet-1317	305	10	erythema	erythema	ADJ
admet-1317	305	11	and	and	CCONJ
admet-1317	305	12	edema	edema	NOUN
admet-1317	305	13	from	from	ADP
admet-1317	305	14	the	the	DET
admet-1317	305	15	skin	skin	NOUN
admet-1317	305	16	sites	site	NOUN
admet-1317	305	17	treated	treat	VERB
admet-1317	305	18	with	with	ADP
admet-1317	305	19	mn	mn	PROPN
admet-1317	305	20	arrays	array	NOUN
admet-1317	305	21	were	be	AUX
admet-1317	305	22	evaluated	evaluate	VERB
admet-1317	305	23	for	for	ADP
admet-1317	305	24	the	the	DET
admet-1317	305	25	rats	rat	NOUN
admet-1317	305	26	at	at	ADP
admet-1317	305	27	1	1	NUM
admet-1317	305	28	,	,	PUNCT
admet-1317	305	29	24	24	NUM
admet-1317	305	30	and	and	CCONJ
admet-1317	305	31	72	72	NUM
admet-1317	305	32	hours	hour	NOUN
admet-1317	306	1	[	[	X
admet-1317	306	2	46	46	NUM
admet-1317	306	3	]	]	PUNCT
admet-1317	306	4	.	.	PUNCT
admet-1317	307	1	as	as	SCONJ
admet-1317	307	2	shown	show	VERB
admet-1317	307	3	in	in	ADP
admet-1317	307	4	figure	figure	NOUN
admet-1317	307	5	10	10	NUM
admet-1317	307	6	,	,	PUNCT
admet-1317	307	7	slight	slight	ADJ
admet-1317	307	8	erythema	erythema	NOUN
admet-1317	308	1	but	but	CCONJ
admet-1317	308	2	no	no	DET
admet-1317	308	3	edema	edema	NOUN
admet-1317	308	4	appeared	appear	VERB
admet-1317	308	5	at	at	ADP
admet-1317	308	6	the	the	DET
admet-1317	308	7	application	application	NOUN
admet-1317	308	8	sites	site	NOUN
admet-1317	308	9	at	at	ADP
admet-1317	308	10	one	one	NUM
admet-1317	308	11	hour	hour	NOUN
admet-1317	308	12	and	and	CCONJ
admet-1317	308	13	disappeared	disappear	VERB
admet-1317	308	14	within	within	ADP
admet-1317	308	15	24	24	NUM
admet-1317	308	16	hours	hour	NOUN
admet-1317	308	17	in	in	ADP
admet-1317	308	18	comparison	comparison	NOUN
admet-1317	308	19	with	with	ADP
admet-1317	308	20	a	a	DET
admet-1317	308	21	hypodermic	hypodermic	ADJ
admet-1317	308	22	needle	needle	NOUN
admet-1317	308	23	.	.	PUNCT
admet-1317	309	1	the	the	DET
admet-1317	309	2	p.i.i	p.i.i	NOUN
admet-1317	309	3	.	.	PUNCT
admet-1317	309	4	of	of	ADP
admet-1317	309	5	the	the	DET
admet-1317	309	6	mn	mn	PROPN
admet-1317	309	7	arrays	array	NOUN
admet-1317	309	8	was	be	AUX
admet-1317	309	9	calculated	calculate	VERB
admet-1317	309	10	to	to	PART
admet-1317	309	11	be	be	AUX
admet-1317	309	12	1.7	1.7	NUM
admet-1317	309	13	.	.	PUNCT
admet-1317	310	1	the	the	DET
admet-1317	310	2	slight	slight	ADJ
admet-1317	310	3	redness	redness	NOUN
admet-1317	310	4	that	that	PRON
admet-1317	310	5	was	be	AUX
admet-1317	310	6	seen	see	VERB
admet-1317	310	7	on	on	ADP
admet-1317	310	8	the	the	DET
admet-1317	310	9	skin	skin	NOUN
admet-1317	310	10	site	site	NOUN
admet-1317	310	11	one	one	NUM
admet-1317	310	12	hour	hour	NOUN
admet-1317	310	13	following	follow	VERB
admet-1317	310	14	the	the	DET
admet-1317	310	15	removal	removal	NOUN
admet-1317	310	16	of	of	ADP
admet-1317	310	17	the	the	DET
admet-1317	310	18	mns	mns	PROPN
admet-1317	310	19	,	,	PUNCT
admet-1317	310	20	suggests	suggest	VERB
admet-1317	310	21	that	that	SCONJ
admet-1317	310	22	the	the	DET
admet-1317	310	23	physical	physical	ADJ
admet-1317	310	24	compression	compression	NOUN
admet-1317	310	25	during	during	ADP
admet-1317	310	26	the	the	DET
admet-1317	310	27	application	application	NOUN
admet-1317	310	28	of	of	ADP
admet-1317	310	29	mns	mns	PROPN
admet-1317	310	30	may	may	AUX
admet-1317	310	31	cause	cause	VERB
admet-1317	310	32	this	this	DET
admet-1317	310	33	skin	skin	NOUN
admet-1317	310	34	redness	redness	NOUN
admet-1317	310	35	.	.	PUNCT
admet-1317	311	1	however	however	ADV
admet-1317	311	2	,	,	PUNCT
admet-1317	311	3	this	this	DET
admet-1317	311	4	redness	redness	NOUN
admet-1317	311	5	disappeared	disappear	VERB
admet-1317	311	6	24	24	NUM
admet-1317	311	7	hours	hour	NOUN
admet-1317	311	8	and	and	CCONJ
admet-1317	311	9	72	72	NUM
admet-1317	311	10	hours	hour	NOUN
admet-1317	311	11	after	after	ADP
admet-1317	311	12	the	the	DET
admet-1317	311	13	application	application	NOUN
admet-1317	311	14	of	of	ADP
admet-1317	311	15	mns	mns	PROPN
admet-1317	311	16	.	.	PUNCT
admet-1317	312	1	therefore	therefore	ADV
admet-1317	312	2	,	,	PUNCT
admet-1317	312	3	these	these	DET
admet-1317	312	4	findings	finding	NOUN
admet-1317	312	5	and	and	CCONJ
admet-1317	312	6	according	accord	VERB
admet-1317	312	7	to	to	PART
admet-1317	312	8	draize	draize	VERB
admet-1317	312	9	dermal	dermal	ADJ
admet-1317	312	10	scoring	scoring	NOUN
admet-1317	312	11	criteria	criterion	NOUN
admet-1317	312	12	indicated	indicate	VERB
admet-1317	312	13	that	that	SCONJ
admet-1317	312	14	the	the	DET
admet-1317	312	15	irritation	irritation	NOUN
admet-1317	312	16	and	and	CCONJ
admet-1317	312	17	skin	skin	NOUN
admet-1317	312	18	damage	damage	NOUN
admet-1317	312	19	caused	cause	VERB
admet-1317	312	20	by	by	ADP
admet-1317	312	21	ha	ha	PROPN
admet-1317	312	22	mn	mn	PROPN
admet-1317	312	23	arrays	array	NOUN
admet-1317	312	24	were	be	AUX
admet-1317	312	25	slight	slight	ADJ
admet-1317	312	26	[	[	X
admet-1317	312	27	27	27	NUM
admet-1317	312	28	]	]	PUNCT
admet-1317	312	29	.	.	PUNCT
admet-1317	313	1	whereas	whereas	SCONJ
admet-1317	313	2	the	the	DET
admet-1317	313	3	hypodermic	hypodermic	ADJ
admet-1317	313	4	syringe	syringe	NOUN
admet-1317	313	5	has	have	AUX
admet-1317	313	6	resulted	result	VERB
admet-1317	313	7	in	in	ADP
admet-1317	313	8	bleeding	bleeding	NOUN
admet-1317	313	9	and	and	CCONJ
admet-1317	313	10	a	a	DET
admet-1317	313	11	dramatic	dramatic	ADJ
admet-1317	313	12	scar	scar	NOUN
admet-1317	313	13	which	which	PRON
admet-1317	313	14	was	be	AUX
admet-1317	313	15	obvious	obvious	ADJ
admet-1317	313	16	even	even	ADV
admet-1317	313	17	72	72	NUM
admet-1317	313	18	hours	hour	NOUN
admet-1317	313	19	following	follow	VERB
admet-1317	313	20	the	the	DET
admet-1317	313	21	application	application	NOUN
admet-1317	313	22	of	of	ADP
admet-1317	313	23	the	the	DET
admet-1317	313	24	hypodermic	hypodermic	ADJ
admet-1317	313	25	needle	needle	NOUN
admet-1317	313	26	.	.	PUNCT
admet-1317	314	1	figure	figure	NOUN
admet-1317	314	2	10	10	NUM
admet-1317	314	3	.	.	PUNCT
admet-1317	315	1	images	image	NOUN
admet-1317	315	2	of	of	ADP
admet-1317	315	3	skin	skin	NOUN
admet-1317	315	4	irritation	irritation	NOUN
admet-1317	315	5	following	follow	VERB
admet-1317	315	6	the	the	DET
admet-1317	315	7	application	application	NOUN
admet-1317	315	8	of	of	ADP
admet-1317	315	9	(	(	PUNCT
admet-1317	315	10	a	a	X
admet-1317	315	11	)	)	PUNCT
admet-1317	315	12	ha	ha	INTJ
admet-1317	315	13	mn	mn	PROPN
admet-1317	315	14	arrays	array	VERB
admet-1317	315	15	f11	f11	PROPN
admet-1317	315	16	and	and	CCONJ
admet-1317	315	17	(	(	PUNCT
admet-1317	315	18	b	b	NOUN
admet-1317	315	19	)	)	PUNCT
admet-1317	315	20	conventional	conventional	ADJ
admet-1317	315	21	hypodermic	hypodermic	ADJ
admet-1317	315	22	syringe	syringe	NOUN
admet-1317	315	23	on	on	ADP
admet-1317	315	24	rat	rat	NOUN
admet-1317	315	25	skin	skin	NOUN
admet-1317	315	26	at	at	ADP
admet-1317	315	27	1	1	NUM
admet-1317	315	28	h	h	NOUN
admet-1317	315	29	,	,	PUNCT
admet-1317	315	30	24	24	NUM
admet-1317	315	31	h	h	NOUN
admet-1317	315	32	and	and	CCONJ
admet-1317	315	33	72	72	NUM
admet-1317	315	34	h.	h.	NOUN
admet-1317	315	35	conclusions	conclusion	NOUN
admet-1317	315	36	the	the	DET
admet-1317	315	37	current	current	ADJ
admet-1317	315	38	study	study	NOUN
admet-1317	315	39	revealed	reveal	VERB
admet-1317	315	40	for	for	ADP
admet-1317	315	41	the	the	DET
admet-1317	315	42	first	first	ADJ
admet-1317	315	43	time	time	NOUN
admet-1317	315	44	the	the	DET
admet-1317	315	45	potential	potential	NOUN
admet-1317	315	46	of	of	ADP
admet-1317	315	47	ha	ha	INTJ
admet-1317	315	48	dissolving	dissolve	VERB
admet-1317	315	49	mn	mn	PROPN
admet-1317	315	50	arrays	array	VERB
admet-1317	315	51	for	for	ADP
admet-1317	315	52	efficient	efficient	ADJ
admet-1317	315	53	transdermal	transdermal	ADJ
admet-1317	315	54	delivery	delivery	NOUN
admet-1317	315	55	of	of	ADP
admet-1317	315	56	lt-4	lt-4	NOUN
admet-1317	315	57	sodium	sodium	NOUN
admet-1317	315	58	by	by	ADP
admet-1317	315	59	overcoming	overcome	VERB
admet-1317	315	60	the	the	DET
admet-1317	315	61	stratum	stratum	NOUN
admet-1317	315	62	corneum	corneum	NOUN
admet-1317	315	63	barrier	barrier	NOUN
admet-1317	315	64	.	.	PUNCT
admet-1317	316	1	additionally	additionally	ADV
admet-1317	316	2	,	,	PUNCT
admet-1317	316	3	this	this	DET
admet-1317	316	4	work	work	NOUN
admet-1317	316	5	clearly	clearly	ADV
admet-1317	316	6	demonstrates	demonstrate	VERB
admet-1317	316	7	the	the	DET
admet-1317	316	8	benefits	benefit	NOUN
admet-1317	316	9	of	of	ADP
admet-1317	316	10	ha	ha	INTJ
admet-1317	316	11	mn	mn	PROPN
admet-1317	316	12	arrays	array	VERB
admet-1317	316	13	in	in	ADP
admet-1317	316	14	enhancing	enhance	VERB
admet-1317	316	15	skin	skin	NOUN
admet-1317	316	16	permeation	permeation	NOUN
admet-1317	316	17	of	of	ADP
admet-1317	316	18	drugs	drug	NOUN
admet-1317	316	19	with	with	ADP
admet-1317	316	20	poor	poor	ADJ
admet-1317	316	21	permeability	permeability	NOUN
admet-1317	316	22	characteristics	characteristic	NOUN
admet-1317	316	23	.	.	PUNCT
admet-1317	317	1	the	the	DET
admet-1317	317	2	lt-4	lt-4	ADJ
admet-1317	317	3	sodium	sodium	NOUN
admet-1317	317	4	loaded	load	VERB
admet-1317	317	5	ha	ha	INTJ
admet-1317	317	6	mn	mn	PROPN
admet-1317	317	7	arrays	array	NOUN
admet-1317	317	8	represent	represent	VERB
admet-1317	317	9	a	a	DET
admet-1317	317	10	minimally	minimally	ADV
admet-1317	317	11	invasive	invasive	ADJ
admet-1317	317	12	system	system	NOUN
admet-1317	317	13	that	that	PRON
admet-1317	317	14	showed	show	VERB
admet-1317	317	15	excellent	excellent	ADJ
admet-1317	317	16	skin	skin	NOUN
admet-1317	317	17	insertion	insertion	NOUN
admet-1317	317	18	with	with	ADP
admet-1317	317	19	rapid	rapid	ADJ
admet-1317	317	20	dissolution	dissolution	NOUN
admet-1317	317	21	and	and	CCONJ
admet-1317	317	22	release	release	NOUN
admet-1317	317	23	of	of	ADP
admet-1317	317	24	lt-4	lt-4	NOUN
admet-1317	317	25	sodium	sodium	NOUN
admet-1317	317	26	and	and	CCONJ
admet-1317	317	27	superior	superior	ADJ
admet-1317	317	28	transdermal	transdermal	ADJ
admet-1317	317	29	delivery	delivery	NOUN
admet-1317	317	30	in	in	ADP
admet-1317	317	31	comparison	comparison	NOUN
admet-1317	317	32	to	to	PART
admet-1317	317	33	control	control	VERB
admet-1317	317	34	preparations	preparation	NOUN
admet-1317	317	35	.	.	PUNCT
admet-1317	318	1	thus	thus	ADV
admet-1317	318	2	,	,	PUNCT
admet-1317	318	3	they	they	PRON
admet-1317	318	4	may	may	AUX
admet-1317	318	5	provide	provide	VERB
admet-1317	318	6	a	a	DET
admet-1317	318	7	feasible	feasible	ADJ
admet-1317	318	8	and	and	CCONJ
admet-1317	318	9	convenient	convenient	ADJ
admet-1317	318	10	alternative	alternative	ADJ
admet-1317	318	11	approach	approach	NOUN
admet-1317	318	12	for	for	ADP
admet-1317	318	13	oral	oral	ADJ
admet-1317	318	14	administration	administration	NOUN
admet-1317	318	15	,	,	PUNCT
admet-1317	318	16	which	which	PRON
admet-1317	318	17	is	be	AUX
admet-1317	318	18	accompanied	accompany	VERB
admet-1317	318	19	by	by	ADP
admet-1317	318	20	variable	variable	ADJ
admet-1317	318	21	rate	rate	NOUN
admet-1317	318	22	and	and	CCONJ
admet-1317	318	23	extent	extent	NOUN
admet-1317	318	24	of	of	ADP
admet-1317	318	25	lt-4	lt-4	NOUN
admet-1317	318	26	sodium	sodium	NOUN
admet-1317	318	27	absorption	absorption	NOUN
admet-1317	318	28	.	.	PUNCT
admet-1317	319	1	however	however	ADV
admet-1317	319	2	,	,	PUNCT
admet-1317	319	3	further	far	ADV
admet-1317	319	4	in	in	ADP
admet-1317	319	5	vivo	vivo	ADJ
admet-1317	319	6	studies	study	NOUN
admet-1317	319	7	are	be	AUX
admet-1317	319	8	required	require	VERB
admet-1317	319	9	to	to	PART
admet-1317	319	10	confirm	confirm	VERB
admet-1317	319	11	the	the	DET
admet-1317	319	12	mn	mn	PROPN
admet-1317	319	13	arrays	array	VERB
admet-1317	319	14	’	'	PUNCT
admet-1317	319	15	efficacy	efficacy	NOUN
admet-1317	319	16	and	and	CCONJ
admet-1317	319	17	safety	safety	NOUN
admet-1317	319	18	for	for	ADP
admet-1317	319	19	clinical	clinical	ADJ
admet-1317	319	20	use	use	NOUN
admet-1317	319	21	.	.	PUNCT
admet-1317	320	1	acknowledgements	acknowledgement	NOUN
admet-1317	320	2	:	:	PUNCT
admet-1317	320	3	the	the	DET
admet-1317	320	4	authors	author	NOUN
admet-1317	320	5	would	would	AUX
admet-1317	320	6	like	like	VERB
admet-1317	320	7	to	to	PART
admet-1317	320	8	thank	thank	VERB
admet-1317	320	9	mustansiriyah	mustansiriyah	PROPN
admet-1317	320	10	university	university	PROPN
admet-1317	320	11	(	(	PUNCT
admet-1317	320	12	www.uomustansiriyah.edu.iq	www.uomustansiriyah.edu.iq	NOUN
admet-1317	320	13	)	)	PUNCT
admet-1317	320	14	baghdad	baghdad	PROPN
admet-1317	320	15	-	-	PUNCT
admet-1317	320	16	iraq	iraq	PROPN
admet-1317	320	17	for	for	ADP
admet-1317	320	18	its	its	PRON
admet-1317	320	19	support	support	NOUN
admet-1317	320	20	in	in	ADP
admet-1317	320	21	the	the	DET
admet-1317	320	22	present	present	ADJ
admet-1317	320	23	work	work	NOUN
admet-1317	320	24	.	.	PUNCT
admet-1317	321	1	funding	funding	NOUN
admet-1317	321	2	:	:	PUNCT
admet-1317	321	3	this	this	DET
admet-1317	321	4	research	research	NOUN
admet-1317	321	5	did	do	AUX
admet-1317	321	6	not	not	PART
admet-1317	321	7	receive	receive	VERB
admet-1317	321	8	any	any	DET
admet-1317	321	9	specific	specific	ADJ
admet-1317	321	10	grant	grant	NOUN
admet-1317	321	11	from	from	ADP
admet-1317	321	12	funding	fund	VERB
admet-1317	321	13	agencies	agency	NOUN
admet-1317	321	14	in	in	ADP
admet-1317	321	15	the	the	DET
admet-1317	321	16	public	public	ADJ
admet-1317	321	17	,	,	PUNCT
admet-1317	321	18	commercial	commercial	ADJ
admet-1317	321	19	,	,	PUNCT
admet-1317	321	20	or	or	CCONJ
admet-1317	321	21	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	VERB
admet-1317	321	22	http://www.uomustansiriyah.edu.iq/	http://www.uomustansiriyah.edu.iq/	PROPN
admet-1317	321	23	r.f	r.f	PROPN
admet-1317	321	24	.	.	PROPN
admet-1317	321	25	ghazi	ghazi	PROPN
admet-1317	321	26	and	and	CCONJ
admet-1317	321	27	m.h	m.h	PROPN
admet-1317	321	28	.	.	PROPN
admet-1317	321	29	al	al	PROPN
admet-1317	321	30	-	-	PUNCT
admet-1317	321	31	mayahy	mayahy	PROPN
admet-1317	321	32	admet	admet	PROPN
admet-1317	321	33	&	&	CCONJ
admet-1317	321	34	dmpk	dmpk	PROPN
admet-1317	321	35	10(3	10(3	NUM
admet-1317	321	36	)	)	PUNCT
admet-1317	321	37	(	(	PUNCT
admet-1317	321	38	2022	2022	NUM
admet-1317	321	39	)	)	PUNCT
admet-1317	321	40	213	213	NUM
admet-1317	321	41	-	-	SYM
admet-1317	321	42	230	230	NUM
admet-1317	321	43	228	228	NUM
admet-1317	321	44	not	not	PART
admet-1317	321	45	-	-	PUNCT
admet-1317	321	46	for	for	ADP
admet-1317	321	47	-	-	PUNCT
admet-1317	321	48	profit	profit	NOUN
admet-1317	321	49	sectors	sector	NOUN
admet-1317	321	50	.	.	PUNCT
admet-1317	322	1	conflict	conflict	NOUN
admet-1317	322	2	of	of	ADP
admet-1317	322	3	interest	interest	NOUN
admet-1317	322	4	:	:	PUNCT
admet-1317	322	5	the	the	DET
admet-1317	322	6	authors	author	NOUN
admet-1317	322	7	declare	declare	VERB
admet-1317	322	8	no	no	DET
admet-1317	322	9	conflict	conflict	NOUN
admet-1317	322	10	of	of	ADP
admet-1317	322	11	interest	interest	NOUN
admet-1317	322	12	.	.	PUNCT
admet-1317	323	1	references	reference	NOUN
admet-1317	323	2	[	[	X
admet-1317	323	3	1	1	NUM
admet-1317	323	4	]	]	PUNCT
admet-1317	323	5	m.	m.	NOUN
admet-1317	323	6	skelin	skelin	PROPN
admet-1317	323	7	,	,	PUNCT
admet-1317	323	8	t.	t.	PROPN
admet-1317	323	9	lucijanic	lucijanic	PROPN
admet-1317	323	10	,	,	PUNCT
admet-1317	323	11	d.	d.	PROPN
admet-1317	323	12	amidzic	amidzic	PROPN
admet-1317	323	13	klaric	klaric	PROPN
admet-1317	323	14	,	,	PUNCT
admet-1317	323	15	a.	a.	NOUN
admet-1317	323	16	resic	resic	NOUN
admet-1317	323	17	,	,	PUNCT
admet-1317	323	18	m.	m.	PROPN
admet-1317	323	19	bakula	bakula	PROPN
admet-1317	323	20	,	,	PUNCT
admet-1317	323	21	a.m.	a.m.	PROPN
admet-1317	323	22	liberati	liberati	PROPN
admet-1317	323	23	-	-	PUNCT
admet-1317	323	24	cizmek	cizmek	PROPN
admet-1317	323	25	,	,	PUNCT
admet-1317	323	26	h.	h.	PROPN
admet-1317	323	27	gharib	gharib	PROPN
admet-1317	323	28	,	,	PUNCT
admet-1317	323	29	d.	d.	PROPN
admet-1317	323	30	rahelic	rahelic	PROPN
admet-1317	323	31	.	.	PUNCT
admet-1317	324	1	factors	factor	NOUN
admet-1317	324	2	affecting	affect	VERB
admet-1317	324	3	gastrointestinal	gastrointestinal	ADJ
admet-1317	324	4	absorption	absorption	NOUN
admet-1317	324	5	of	of	ADP
admet-1317	324	6	levothyroxine	levothyroxine	PROPN
admet-1317	324	7	:	:	PUNCT
admet-1317	324	8	a	a	DET
admet-1317	324	9	review	review	NOUN
admet-1317	324	10	.	.	PUNCT
admet-1317	325	1	clin	clin	PROPN
admet-1317	325	2	.	.	PUNCT
admet-1317	326	1	ther	ther	PROPN
admet-1317	326	2	.	.	PUNCT
admet-1317	327	1	39	39	NUM
admet-1317	327	2	(	(	PUNCT
admet-1317	327	3	2017	2017	NUM
admet-1317	327	4	)	)	PUNCT
admet-1317	327	5	378	378	NUM
admet-1317	327	6	-	-	SYM
admet-1317	327	7	403	403	NUM
admet-1317	327	8	.	.	PUNCT
admet-1317	328	1	https://doi.org/10.1016/j.clinthera.2017.01.005	https://doi.org/10.1016/j.clinthera.2017.01.005	VERB
admet-1317	328	2	.	.	PUNCT
admet-1317	329	1	[	[	X
admet-1317	329	2	2	2	X
admet-1317	329	3	]	]	PUNCT
admet-1317	329	4	j.	j.	PROPN
admet-1317	329	5	jonklaas	jonklaas	PROPN
admet-1317	329	6	,	,	PUNCT
admet-1317	329	7	a.c	a.c	PROPN
admet-1317	329	8	.	.	PROPN
admet-1317	329	9	bianco	bianco	PROPN
admet-1317	329	10	,	,	PUNCT
admet-1317	329	11	a.j	a.j	PROPN
admet-1317	329	12	.	.	PROPN
admet-1317	329	13	bauer	bauer	PROPN
admet-1317	329	14	,	,	PUNCT
admet-1317	329	15	k.d	k.d	PROPN
admet-1317	329	16	.	.	PROPN
admet-1317	329	17	burman	burman	PROPN
admet-1317	329	18	,	,	PUNCT
admet-1317	329	19	a.r	a.r	PROPN
admet-1317	329	20	.	.	PROPN
admet-1317	329	21	cappola	cappola	PROPN
admet-1317	329	22	,	,	PUNCT
admet-1317	329	23	f.s	f.s	PROPN
admet-1317	329	24	.	.	PROPN
admet-1317	329	25	celi	celi	PROPN
admet-1317	329	26	,	,	PUNCT
admet-1317	329	27	d.s	d.s	PROPN
admet-1317	329	28	.	.	PROPN
admet-1317	329	29	cooper	cooper	PROPN
admet-1317	329	30	,	,	PUNCT
admet-1317	329	31	b.w	b.w	PROPN
admet-1317	329	32	.	.	PROPN
admet-1317	329	33	kim	kim	PROPN
admet-1317	329	34	,	,	PUNCT
admet-1317	329	35	r.p	r.p	PROPN
admet-1317	329	36	.	.	PROPN
admet-1317	329	37	peeters	peeters	PROPN
admet-1317	329	38	,	,	PUNCT
admet-1317	329	39	m.s	m.s	PROPN
admet-1317	329	40	.	.	PROPN
admet-1317	329	41	rosenthal	rosenthal	PROPN
admet-1317	329	42	,	,	PUNCT
admet-1317	329	43	a.m.	a.m.	PROPN
admet-1317	329	44	sawka	sawka	PROPN
admet-1317	329	45	,	,	PUNCT
admet-1317	329	46	r.	r.	PROPN
admet-1317	329	47	american	american	PROPN
admet-1317	329	48	thyroid	thyroid	PROPN
admet-1317	329	49	association	association	PROPN
admet-1317	329	50	task	task	PROPN
admet-1317	329	51	force	force	NOUN
admet-1317	329	52	on	on	ADP
admet-1317	329	53	thyroid	thyroid	NOUN
admet-1317	329	54	hormone	hormone	NOUN
admet-1317	329	55	.	.	PUNCT
admet-1317	330	1	guidelines	guideline	NOUN
admet-1317	330	2	for	for	ADP
admet-1317	330	3	the	the	DET
admet-1317	330	4	treatment	treatment	NOUN
admet-1317	330	5	of	of	ADP
admet-1317	330	6	hypothyroidism	hypothyroidism	NOUN
admet-1317	330	7	:	:	PUNCT
admet-1317	330	8	prepared	prepare	VERB
admet-1317	330	9	by	by	ADP
admet-1317	330	10	the	the	DET
admet-1317	330	11	american	american	PROPN
admet-1317	330	12	thyroid	thyroid	PROPN
admet-1317	330	13	association	association	PROPN
admet-1317	330	14	task	task	PROPN
admet-1317	330	15	force	force	NOUN
admet-1317	330	16	on	on	ADP
admet-1317	330	17	thyroid	thyroid	NOUN
admet-1317	330	18	hormone	hormone	NOUN
admet-1317	330	19	replacement	replacement	NOUN
admet-1317	330	20	.	.	PUNCT
admet-1317	331	1	thyroid	thyroid	NOUN
admet-1317	331	2	24	24	NUM
admet-1317	331	3	(	(	PUNCT
admet-1317	331	4	2014	2014	NUM
admet-1317	331	5	)	)	PUNCT
admet-1317	331	6	1670	1670	NUM
admet-1317	331	7	-	-	SYM
admet-1317	331	8	1751	1751	NUM
admet-1317	331	9	.	.	PUNCT
admet-1317	332	1	https://doi.org/10.1089/thy.2014.0028	https://doi.org/10.1089/thy.2014.0028	NOUN
admet-1317	332	2	.	.	PUNCT
admet-1317	333	1	[	[	X
admet-1317	333	2	3	3	X
admet-1317	333	3	]	]	X
admet-1317	333	4	k.b	k.b	PROPN
admet-1317	333	5	.	.	PROPN
admet-1317	333	6	ain	ain	PROPN
admet-1317	333	7	,	,	PUNCT
admet-1317	333	8	s.	s.	PROPN
admet-1317	333	9	refetoff	refetoff	PROPN
admet-1317	333	10	,	,	PUNCT
admet-1317	333	11	h.g	h.g	PROPN
admet-1317	333	12	.	.	PROPN
admet-1317	333	13	fein	fein	PROPN
admet-1317	333	14	,	,	PUNCT
admet-1317	333	15	b.d	b.d	PROPN
admet-1317	333	16	.	.	PROPN
admet-1317	333	17	weintraub	weintraub	PROPN
admet-1317	333	18	.	.	PUNCT
admet-1317	334	1	pseudomalabsorption	pseudomalabsorption	NOUN
admet-1317	334	2	of	of	ADP
admet-1317	334	3	levothyroxine	levothyroxine	PROPN
admet-1317	334	4	.	.	PUNCT
admet-1317	335	1	jama	jama	PROPN
admet-1317	335	2	266	266	NUM
admet-1317	335	3	(	(	PUNCT
admet-1317	335	4	1991	1991	NUM
admet-1317	335	5	)	)	PUNCT
admet-1317	335	6	2118	2118	NUM
admet-1317	335	7	-	-	SYM
admet-1317	335	8	2120	2120	NUM
admet-1317	335	9	.	.	PUNCT
admet-1317	336	1	https://doi.org/10.1001/jama.1991.03470150090036	https://doi.org/10.1001/jama.1991.03470150090036	PROPN
admet-1317	336	2	.	.	PUNCT
admet-1317	337	1	[	[	X
admet-1317	337	2	4	4	NUM
admet-1317	337	3	]	]	X
admet-1317	337	4	m.r	m.r	PROPN
admet-1317	337	5	.	.	PROPN
admet-1317	337	6	prausnitz	prausnitz	NOUN
admet-1317	337	7	.	.	PUNCT
admet-1317	338	1	microneedles	microneedle	NOUN
admet-1317	338	2	for	for	ADP
admet-1317	338	3	transdermal	transdermal	ADJ
admet-1317	338	4	drug	drug	NOUN
admet-1317	338	5	delivery	delivery	NOUN
admet-1317	338	6	.	.	PUNCT
admet-1317	339	1	adv	adv	PROPN
admet-1317	339	2	.	.	PUNCT
admet-1317	339	3	drug	drug	PROPN
admet-1317	339	4	deliv	deliv	PROPN
admet-1317	339	5	.	.	PUNCT
admet-1317	340	1	rev	rev	PROPN
admet-1317	340	2	.	.	PROPN
admet-1317	340	3	56	56	NUM
admet-1317	340	4	(	(	PUNCT
admet-1317	340	5	2004	2004	NUM
admet-1317	340	6	)	)	PUNCT
admet-1317	341	1	581	581	NUM
admet-1317	341	2	-	-	SYM
admet-1317	341	3	587	587	NUM
admet-1317	341	4	.	.	PUNCT
admet-1317	342	1	https://doi.org/10.1016/j.addr.2003.10.023	https://doi.org/10.1016/j.addr.2003.10.023	NUM
admet-1317	342	2	.	.	PUNCT
admet-1317	343	1	[	[	X
admet-1317	343	2	5	5	X
admet-1317	343	3	]	]	X
admet-1317	343	4	d.v	d.v	PROPN
admet-1317	343	5	.	.	PROPN
admet-1317	343	6	mcallister	mcallister	PROPN
admet-1317	343	7	,	,	PUNCT
admet-1317	343	8	p.m.	p.m.	PROPN
admet-1317	343	9	wang	wang	PROPN
admet-1317	343	10	,	,	PUNCT
admet-1317	343	11	s.p	s.p	PROPN
admet-1317	343	12	.	.	PROPN
admet-1317	343	13	davis	davis	PROPN
admet-1317	343	14	,	,	PUNCT
admet-1317	343	15	j.h	j.h	PROPN
admet-1317	343	16	.	.	PROPN
admet-1317	343	17	park	park	PROPN
admet-1317	343	18	,	,	PUNCT
admet-1317	343	19	p.j	p.j	PROPN
admet-1317	343	20	.	.	PROPN
admet-1317	343	21	canatella	canatella	PROPN
admet-1317	343	22	,	,	PUNCT
admet-1317	343	23	m.g	m.g	PROPN
admet-1317	343	24	.	.	PROPN
admet-1317	343	25	allen	allen	PROPN
admet-1317	343	26	,	,	PUNCT
admet-1317	343	27	m.r	m.r	PROPN
admet-1317	343	28	.	.	PROPN
admet-1317	343	29	prausnitz	prausnitz	PROPN
admet-1317	343	30	.	.	PUNCT
admet-1317	344	1	microfabricated	microfabricated	ADJ
admet-1317	344	2	needles	needle	NOUN
admet-1317	344	3	for	for	ADP
admet-1317	344	4	transdermal	transdermal	ADJ
admet-1317	344	5	delivery	delivery	NOUN
admet-1317	344	6	of	of	ADP
admet-1317	344	7	macromolecules	macromolecule	NOUN
admet-1317	344	8	and	and	CCONJ
admet-1317	344	9	nanoparticles	nanoparticle	NOUN
admet-1317	344	10	:	:	PUNCT
admet-1317	344	11	fabrication	fabrication	NOUN
admet-1317	344	12	methods	method	NOUN
admet-1317	344	13	and	and	CCONJ
admet-1317	344	14	transport	transport	NOUN
admet-1317	344	15	studies	study	NOUN
admet-1317	344	16	.	.	PUNCT
admet-1317	345	1	proc	proc	PROPN
admet-1317	345	2	.	.	PUNCT
admet-1317	346	1	natl	natl	PROPN
admet-1317	346	2	.	.	PUNCT
admet-1317	347	1	acad	acad	PROPN
admet-1317	347	2	.	.	PUNCT
admet-1317	348	1	sci	sci	PROPN
admet-1317	348	2	.	.	PROPN
admet-1317	348	3	usa	usa	PROPN
admet-1317	348	4	100	100	NUM
admet-1317	348	5	(	(	PUNCT
admet-1317	348	6	2003	2003	NUM
admet-1317	348	7	)	)	PUNCT
admet-1317	348	8	13755	13755	NUM
admet-1317	348	9	-	-	SYM
admet-1317	348	10	13760	13760	NUM
admet-1317	348	11	.	.	PUNCT
admet-1317	349	1	https://doi.org/10.1073/pnas.2331316100	https://doi.org/10.1073/pnas.2331316100	NOUN
admet-1317	349	2	.	.	PUNCT
admet-1317	350	1	[	[	X
admet-1317	350	2	6	6	NUM
admet-1317	350	3	]	]	PUNCT
admet-1317	350	4	k.	k.	PROPN
admet-1317	350	5	ita	ita	PROPN
admet-1317	350	6	.	.	PUNCT
admet-1317	351	1	transdermal	transdermal	ADJ
admet-1317	351	2	delivery	delivery	NOUN
admet-1317	351	3	of	of	ADP
admet-1317	351	4	drugs	drug	NOUN
admet-1317	351	5	with	with	ADP
admet-1317	351	6	microneedles	microneedle	NOUN
admet-1317	351	7	—	—	PUNCT
admet-1317	351	8	potential	potential	ADJ
admet-1317	351	9	and	and	CCONJ
admet-1317	351	10	challenges	challenge	NOUN
admet-1317	351	11	.	.	PUNCT
admet-1317	352	1	pharmaceutics	pharmaceutic	NOUN
admet-1317	352	2	7	7	NUM
admet-1317	352	3	(	(	PUNCT
admet-1317	352	4	2015	2015	NUM
admet-1317	352	5	)	)	PUNCT
admet-1317	352	6	90	90	NUM
admet-1317	352	7	-	-	SYM
admet-1317	352	8	105	105	NUM
admet-1317	352	9	.	.	PUNCT
admet-1317	352	10	https://doi.org/10.3390/pharmaceutics7030090	https://doi.org/10.3390/pharmaceutics7030090	NOUN
admet-1317	352	11	.	.	PUNCT
admet-1317	353	1	[	[	X
admet-1317	353	2	7	7	X
admet-1317	353	3	]	]	X
admet-1317	353	4	y.	y.	PROPN
admet-1317	353	5	chen	chen	PROPN
admet-1317	353	6	,	,	PUNCT
admet-1317	353	7	b.z	b.z	PROPN
admet-1317	353	8	.	.	PROPN
admet-1317	353	9	chen	chen	PROPN
admet-1317	353	10	,	,	PUNCT
admet-1317	353	11	q.l	q.l	PROPN
admet-1317	353	12	.	.	PROPN
admet-1317	353	13	wang	wang	PROPN
admet-1317	353	14	,	,	PUNCT
admet-1317	353	15	x.	x.	PROPN
admet-1317	353	16	jin	jin	PROPN
admet-1317	353	17	,	,	PUNCT
admet-1317	353	18	x.d	x.d	PROPN
admet-1317	353	19	.	.	PROPN
admet-1317	353	20	guo	guo	PROPN
admet-1317	353	21	.	.	PUNCT
admet-1317	353	22	fabrication	fabrication	NOUN
admet-1317	353	23	of	of	ADP
admet-1317	353	24	coated	coated	ADJ
admet-1317	353	25	polymer	polymer	NOUN
admet-1317	353	26	microneedles	microneedle	NOUN
admet-1317	353	27	for	for	ADP
admet-1317	353	28	transdermal	transdermal	ADJ
admet-1317	353	29	drug	drug	NOUN
admet-1317	353	30	delivery	delivery	NOUN
admet-1317	353	31	.	.	PUNCT
admet-1317	354	1	j.	j.	PROPN
admet-1317	354	2	control	control	PROPN
admet-1317	354	3	.	.	PUNCT
admet-1317	355	1	release	release	VERB
admet-1317	355	2	265	265	NUM
admet-1317	355	3	(	(	PUNCT
admet-1317	355	4	2017	2017	NUM
admet-1317	355	5	)	)	PUNCT
admet-1317	355	6	14	14	NUM
admet-1317	355	7	-	-	SYM
admet-1317	355	8	21	21	NUM
admet-1317	355	9	.	.	PUNCT
admet-1317	356	1	https://doi.org/10.1016/j.jconrel.2017.03.383	https://doi.org/10.1016/j.jconrel.2017.03.383	PROPN
admet-1317	356	2	.	.	PUNCT
admet-1317	357	1	[	[	X
admet-1317	357	2	8	8	NUM
admet-1317	357	3	]	]	PUNCT
admet-1317	357	4	k.	k.	PROPN
admet-1317	357	5	ita	ita	PROPN
admet-1317	357	6	.	.	PUNCT
admet-1317	358	1	dissolving	dissolve	VERB
admet-1317	358	2	microneedles	microneedle	NOUN
admet-1317	358	3	for	for	ADP
admet-1317	358	4	transdermal	transdermal	ADJ
admet-1317	358	5	drug	drug	NOUN
admet-1317	358	6	delivery	delivery	NOUN
admet-1317	358	7	:	:	PUNCT
admet-1317	358	8	advances	advance	NOUN
admet-1317	358	9	and	and	CCONJ
admet-1317	358	10	challenges	challenge	NOUN
admet-1317	358	11	.	.	PUNCT
admet-1317	359	1	biomed	biome	VERB
admet-1317	359	2	.	.	PUNCT
admet-1317	360	1	pharmacother	pharmacother	ADJ
admet-1317	360	2	.	.	PUNCT
admet-1317	361	1	93	93	NUM
admet-1317	361	2	(	(	PUNCT
admet-1317	361	3	2017	2017	NUM
admet-1317	361	4	)	)	PUNCT
admet-1317	361	5	1116	1116	NUM
admet-1317	361	6	-	-	SYM
admet-1317	361	7	1127	1127	NUM
admet-1317	361	8	.	.	PUNCT
admet-1317	362	1	https://doi.org/10.1016/j.biopha.2017.07.019	https://doi.org/10.1016/j.biopha.2017.07.019	X
admet-1317	362	2	.	.	PUNCT
admet-1317	363	1	[	[	X
admet-1317	363	2	9	9	NUM
admet-1317	363	3	]	]	X
admet-1317	363	4	m.s	m.s	PROPN
admet-1317	363	5	.	.	PROPN
admet-1317	363	6	lhernould	lhernould	AUX
admet-1317	363	7	.	.	PUNCT
admet-1317	364	1	optimizing	optimize	VERB
admet-1317	364	2	hollow	hollow	ADJ
admet-1317	364	3	microneedles	microneedle	NOUN
admet-1317	364	4	arrays	array	NOUN
admet-1317	364	5	aimed	aim	VERB
admet-1317	364	6	at	at	ADP
admet-1317	364	7	transdermal	transdermal	ADJ
admet-1317	364	8	drug	drug	NOUN
admet-1317	364	9	delivery	delivery	NOUN
admet-1317	364	10	.	.	PUNCT
admet-1317	365	1	microsystem	microsystem	NOUN
admet-1317	365	2	technologies	technology	NOUN
admet-1317	365	3	19	19	NUM
admet-1317	365	4	(	(	PUNCT
admet-1317	365	5	2013	2013	NUM
admet-1317	365	6	)	)	PUNCT
admet-1317	365	7	1	1	NUM
admet-1317	365	8	-	-	SYM
admet-1317	365	9	8	8	NUM
admet-1317	365	10	.	.	PUNCT
admet-1317	366	1	[	[	X
admet-1317	366	2	10	10	NUM
admet-1317	366	3	]	]	X
admet-1317	366	4	a.a	a.a	PROPN
admet-1317	366	5	.	.	PROPN
admet-1317	366	6	sabeeh	sabeeh	PROPN
admet-1317	366	7	,	,	PUNCT
admet-1317	366	8	a	a	PRON
admet-1317	366	9	..	..	PUNCT
admet-1317	366	10	m.	m.	NOUN
admet-1317	366	11	hussain	hussain	PROPN
admet-1317	366	12	.	.	PUNCT
admet-1317	367	1	the	the	DET
admet-1317	367	2	growing	grow	VERB
admet-1317	367	3	role	role	NOUN
admet-1317	367	4	of	of	ADP
admet-1317	367	5	hydrogel	hydrogel	NOUN
admet-1317	367	6	microneedles	microneedle	NOUN
admet-1317	367	7	in	in	ADP
admet-1317	367	8	transdermal	transdermal	ADJ
admet-1317	367	9	drug	drug	NOUN
admet-1317	367	10	delivery	delivery	NOUN
admet-1317	367	11	.	.	PUNCT
admet-1317	368	1	international	international	ADJ
admet-1317	368	2	journal	journal	PROPN
admet-1317	368	3	of	of	ADP
admet-1317	368	4	drug	drug	NOUN
admet-1317	368	5	delivery	delivery	NOUN
admet-1317	368	6	technology	technology	NOUN
admet-1317	368	7	11	11	NUM
admet-1317	368	8	(	(	PUNCT
admet-1317	368	9	2021	2021	NUM
admet-1317	368	10	)	)	PUNCT
admet-1317	368	11	611	611	NUM
admet-1317	368	12	-	-	SYM
admet-1317	368	13	616	616	NUM
admet-1317	368	14	.	.	PUNCT
admet-1317	369	1	https://doi.org/10.25258/ijddt.11.2.67	https://doi.org/10.25258/ijddt.11.2.67	NOUN
admet-1317	369	2	.	.	PUNCT
admet-1317	370	1	[	[	X
admet-1317	370	2	11	11	NUM
admet-1317	370	3	]	]	PUNCT
admet-1317	370	4	s.	s.	PROPN
admet-1317	370	5	dhivya	dhivya	PROPN
admet-1317	370	6	,	,	PUNCT
admet-1317	370	7	j.	j.	PROPN
admet-1317	370	8	ajita	ajita	PROPN
admet-1317	370	9	,	,	PUNCT
admet-1317	370	10	n.	n.	PROPN
admet-1317	370	11	selvamurugan	selvamurugan	NOUN
admet-1317	370	12	.	.	PUNCT
admet-1317	371	1	metallic	metallic	ADJ
admet-1317	371	2	nanomaterials	nanomaterial	NOUN
admet-1317	371	3	for	for	ADP
admet-1317	371	4	bone	bone	NOUN
admet-1317	371	5	tissue	tissue	NOUN
admet-1317	371	6	engineering	engineering	NOUN
admet-1317	371	7	.	.	PUNCT
admet-1317	372	1	j.	j.	PROPN
admet-1317	372	2	biomed	biome	VERB
admet-1317	372	3	.	.	PUNCT
admet-1317	373	1	nanotechnol	nanotechnol	NOUN
admet-1317	373	2	.	.	PUNCT
admet-1317	374	1	11	11	NUM
admet-1317	374	2	(	(	PUNCT
admet-1317	374	3	2015	2015	NUM
admet-1317	374	4	)	)	PUNCT
admet-1317	374	5	1675	1675	NUM
admet-1317	374	6	-	-	SYM
admet-1317	374	7	1700	1700	NUM
admet-1317	374	8	.	.	PUNCT
admet-1317	375	1	https://doi.org/10.1166/jbn.2015.2115	https://doi.org/10.1166/jbn.2015.2115	PROPN
admet-1317	375	2	.	.	PUNCT
admet-1317	376	1	[	[	X
admet-1317	376	2	12	12	NUM
admet-1317	376	3	]	]	PUNCT
admet-1317	376	4	s.	s.	PROPN
admet-1317	376	5	chen	chen	PROPN
admet-1317	376	6	,	,	PUNCT
admet-1317	376	7	x.	x.	PROPN
admet-1317	376	8	hao	hao	PROPN
admet-1317	376	9	,	,	PUNCT
admet-1317	376	10	x.	x.	PROPN
admet-1317	376	11	liang	liang	PROPN
admet-1317	376	12	,	,	PUNCT
admet-1317	376	13	q.	q.	PROPN
admet-1317	376	14	zhang	zhang	PROPN
admet-1317	376	15	,	,	PUNCT
admet-1317	376	16	c.	c.	PROPN
admet-1317	376	17	zhang	zhang	PROPN
admet-1317	376	18	,	,	PUNCT
admet-1317	376	19	g.	g.	PROPN
admet-1317	376	20	zhou	zhou	PROPN
admet-1317	376	21	,	,	PUNCT
admet-1317	376	22	s.	s.	PROPN
admet-1317	376	23	shen	shen	PROPN
admet-1317	376	24	,	,	PUNCT
admet-1317	376	25	g.	g.	PROPN
admet-1317	376	26	jia	jia	PROPN
admet-1317	376	27	,	,	PUNCT
admet-1317	376	28	j.	j.	PROPN
admet-1317	376	29	zhang	zhang	PROPN
admet-1317	376	30	.	.	PROPN
admet-1317	376	31	inorganic	inorganic	ADJ
admet-1317	376	32	nanomaterials	nanomaterial	NOUN
admet-1317	376	33	as	as	ADP
admet-1317	376	34	carriers	carrier	NOUN
admet-1317	376	35	for	for	ADP
admet-1317	376	36	drug	drug	NOUN
admet-1317	376	37	delivery	delivery	NOUN
admet-1317	376	38	.	.	PUNCT
admet-1317	377	1	journal	journal	PROPN
admet-1317	377	2	of	of	ADP
admet-1317	377	3	biomedical	biomedical	ADJ
admet-1317	377	4	nanotechnology	nanotechnology	NOUN
admet-1317	377	5	12	12	NUM
admet-1317	377	6	(	(	PUNCT
admet-1317	377	7	2016	2016	NUM
admet-1317	377	8	)	)	PUNCT
admet-1317	377	9	1	1	NUM
admet-1317	377	10	-	-	SYM
admet-1317	377	11	27	27	NUM
admet-1317	377	12	.	.	PUNCT
admet-1317	378	1	https://doi.org/10.1166/jbn.2016.2122	https://doi.org/10.1166/jbn.2016.2122	PROPN
admet-1317	378	2	.	.	PUNCT
admet-1317	379	1	[	[	X
admet-1317	379	2	13	13	NUM
admet-1317	379	3	]	]	X
admet-1317	379	4	w.	w.	PROPN
admet-1317	379	5	yu	yu	PROPN
admet-1317	379	6	,	,	PUNCT
admet-1317	379	7	g.	g.	PROPN
admet-1317	379	8	jiang	jiang	PROPN
admet-1317	379	9	,	,	PUNCT
admet-1317	379	10	y.	y.	PROPN
admet-1317	379	11	zhang	zhang	PROPN
admet-1317	379	12	,	,	PUNCT
admet-1317	379	13	d.	d.	PROPN
admet-1317	379	14	liu	liu	PROPN
admet-1317	379	15	,	,	PUNCT
admet-1317	379	16	b.	b.	PROPN
admet-1317	379	17	xu	xu	PROPN
admet-1317	379	18	,	,	PUNCT
admet-1317	379	19	j.	j.	PROPN
admet-1317	379	20	zhou	zhou	PROPN
admet-1317	379	21	.	.	PUNCT
admet-1317	380	1	polymer	polymer	NOUN
admet-1317	380	2	microneedles	microneedle	NOUN
admet-1317	380	3	fabricated	fabricate	VERB
admet-1317	380	4	from	from	ADP
admet-1317	380	5	alginate	alginate	NOUN
admet-1317	380	6	and	and	CCONJ
admet-1317	380	7	hyaluronate	hyaluronate	VERB
admet-1317	380	8	for	for	ADP
admet-1317	380	9	transdermal	transdermal	ADJ
admet-1317	380	10	delivery	delivery	NOUN
admet-1317	380	11	of	of	ADP
admet-1317	380	12	insulin	insulin	NOUN
admet-1317	380	13	.	.	PUNCT
admet-1317	381	1	mater	mater	NOUN
admet-1317	381	2	.	.	PUNCT
admet-1317	382	1	sci	sci	PROPN
admet-1317	382	2	.	.	PUNCT
admet-1317	383	1	eng	eng	PROPN
admet-1317	383	2	.	.	PUNCT
admet-1317	383	3	c	c	PROPN
admet-1317	383	4	mater	mater	NOUN
admet-1317	383	5	.	.	PUNCT
admet-1317	384	1	biol	biol	PROPN
admet-1317	384	2	.	.	PUNCT
admet-1317	385	1	appl	appl	PROPN
admet-1317	385	2	.	.	PROPN
admet-1317	386	1	80	80	NUM
admet-1317	386	2	(	(	PUNCT
admet-1317	386	3	2017	2017	NUM
admet-1317	386	4	)	)	PUNCT
admet-1317	386	5	187196	187196	NUM
admet-1317	386	6	.	.	PUNCT
admet-1317	387	1	https://doi.org/10.1016/j.msec.2017.05.143	https://doi.org/10.1016/j.msec.2017.05.143	NOUN
admet-1317	387	2	.	.	PUNCT
admet-1317	388	1	[	[	X
admet-1317	388	2	14	14	NUM
admet-1317	388	3	]	]	PUNCT
admet-1317	388	4	x.	x.	NOUN
admet-1317	388	5	jin	jin	PROPN
admet-1317	388	6	,	,	PUNCT
admet-1317	388	7	d.d	d.d	PROPN
admet-1317	388	8	.	.	PROPN
admet-1317	388	9	zhu	zhu	PROPN
admet-1317	388	10	,	,	PUNCT
admet-1317	388	11	b.z	b.z	PROPN
admet-1317	388	12	.	.	PROPN
admet-1317	388	13	chen	chen	PROPN
admet-1317	388	14	,	,	PUNCT
admet-1317	388	15	m.	m.	NOUN
admet-1317	388	16	ashfaq	ashfaq	PROPN
admet-1317	388	17	,	,	PUNCT
admet-1317	388	18	x.d	x.d	PROPN
admet-1317	388	19	.	.	PROPN
admet-1317	388	20	guo	guo	PROPN
admet-1317	388	21	.	.	PUNCT
admet-1317	389	1	insulin	insulin	NOUN
admet-1317	389	2	delivery	delivery	NOUN
admet-1317	389	3	systems	system	NOUN
admet-1317	389	4	combined	combine	VERB
admet-1317	389	5	with	with	ADP
admet-1317	389	6	microneedle	microneedle	ADJ
admet-1317	389	7	technology	technology	NOUN
admet-1317	389	8	.	.	PUNCT
admet-1317	390	1	adv	adv	PROPN
admet-1317	390	2	.	.	PUNCT
admet-1317	390	3	drug	drug	PROPN
admet-1317	390	4	deliv	deliv	PROPN
admet-1317	390	5	.	.	PUNCT
admet-1317	391	1	rev	rev	PROPN
admet-1317	391	2	.	.	PROPN
admet-1317	392	1	127	127	NUM
admet-1317	392	2	(	(	PUNCT
admet-1317	392	3	2018	2018	NUM
admet-1317	392	4	)	)	PUNCT
admet-1317	392	5	119	119	NUM
admet-1317	392	6	-	-	SYM
admet-1317	392	7	137	137	NUM
admet-1317	392	8	.	.	PUNCT
admet-1317	393	1	https://doi.org/10.1016/j.addr.2018.03.011	https://doi.org/10.1016/j.addr.2018.03.011	NOUN
admet-1317	393	2	.	.	PUNCT
admet-1317	394	1	[	[	X
admet-1317	394	2	15	15	NUM
admet-1317	394	3	]	]	X
admet-1317	394	4	n.b	n.b	PROPN
admet-1317	394	5	.	.	PROPN
admet-1317	394	6	pajić	pajić	PROPN
admet-1317	394	7	,	,	PUNCT
admet-1317	394	8	s.	s.	PROPN
admet-1317	394	9	vucen	vucen	PROPN
admet-1317	394	10	,	,	PUNCT
admet-1317	394	11	t.	t.	PROPN
admet-1317	394	12	ilić	ilić	PROPN
admet-1317	394	13	,	,	PUNCT
admet-1317	394	14	c.	c.	PROPN
admet-1317	394	15	o'mahony	o'mahony	PROPN
admet-1317	394	16	,	,	PUNCT
admet-1317	394	17	v.	v.	ADP
admet-1317	394	18	dobričić	dobričić	PROPN
admet-1317	394	19	,	,	PUNCT
admet-1317	394	20	s.	s.	PROPN
admet-1317	394	21	savić	savić	PROPN
admet-1317	394	22	.	.	PUNCT
admet-1317	395	1	comparative	comparative	ADJ
admet-1317	395	2	efficacy	efficacy	NOUN
admet-1317	395	3	evaluation	evaluation	NOUN
admet-1317	395	4	of	of	ADP
admet-1317	395	5	different	different	ADJ
admet-1317	395	6	penetration	penetration	NOUN
admet-1317	395	7	enhancement	enhancement	NOUN
admet-1317	395	8	strategies	strategy	NOUN
admet-1317	395	9	for	for	ADP
admet-1317	395	10	dermal	dermal	ADJ
admet-1317	395	11	delivery	delivery	NOUN
admet-1317	395	12	of	of	ADP
admet-1317	395	13	poorly	poorly	ADV
admet-1317	395	14	soluble	soluble	ADJ
admet-1317	395	15	drugs	drug	NOUN
admet-1317	395	16	–	–	PUNCT
admet-1317	395	17	a	a	DET
admet-1317	395	18	case	case	NOUN
admet-1317	395	19	with	with	ADP
admet-1317	395	20	sertaconazole	sertaconazole	NOUN
admet-1317	395	21	nitrate	nitrate	NOUN
admet-1317	395	22	.	.	PUNCT
admet-1317	396	1	european	european	ADJ
admet-1317	396	2	journal	journal	PROPN
admet-1317	396	3	of	of	ADP
admet-1317	396	4	pharmaceutical	pharmaceutical	PROPN
admet-1317	396	5	sciences	science	NOUN
admet-1317	396	6	164	164	NUM
admet-1317	396	7	(	(	PUNCT
admet-1317	396	8	2021	2021	NUM
admet-1317	396	9	)	)	PUNCT
admet-1317	396	10	105895	105895	NUM
admet-1317	396	11	.	.	PUNCT
admet-1317	397	1	https://doi.org/10.1016/j.ejps.2021.105895	https://doi.org/10.1016/j.ejps.2021.105895	VERB
admet-1317	397	2	.	.	PUNCT
admet-1317	398	1	[	[	X
admet-1317	398	2	16	16	NUM
admet-1317	398	3	]	]	X
admet-1317	398	4	i.c	i.c	PROPN
admet-1317	398	5	.	.	PROPN
admet-1317	398	6	lee	lee	PROPN
admet-1317	398	7	,	,	PUNCT
admet-1317	398	8	j.s	j.s	PROPN
admet-1317	398	9	.	.	PUNCT
admet-1317	399	1	he	he	PRON
admet-1317	399	2	,	,	PUNCT
admet-1317	399	3	m.t	m.t	PROPN
admet-1317	399	4	.	.	PROPN
admet-1317	399	5	tsai	tsai	PROPN
admet-1317	399	6	,	,	PUNCT
admet-1317	399	7	k.c	k.c	PROPN
admet-1317	399	8	.	.	PROPN
admet-1317	399	9	lin	lin	PROPN
admet-1317	399	10	.	.	PUNCT
admet-1317	400	1	fabrication	fabrication	NOUN
admet-1317	400	2	of	of	ADP
admet-1317	400	3	a	a	DET
admet-1317	400	4	novel	novel	NOUN
admet-1317	400	5	partially	partially	ADV
admet-1317	400	6	dissolving	dissolve	VERB
admet-1317	400	7	polymer	polymer	NOUN
admet-1317	400	8	microneedle	microneedle	NOUN
admet-1317	400	9	patch	patch	NOUN
admet-1317	400	10	for	for	ADP
admet-1317	400	11	transdermal	transdermal	ADJ
admet-1317	400	12	drug	drug	NOUN
admet-1317	400	13	delivery	delivery	NOUN
admet-1317	400	14	.	.	PUNCT
admet-1317	401	1	j.	j.	PROPN
admet-1317	401	2	mater	mater	PROPN
admet-1317	401	3	.	.	PUNCT
admet-1317	401	4	chem	chem	PROPN
admet-1317	401	5	.	.	PUNCT
admet-1317	402	1	b	b	X
admet-1317	402	2	3	3	NUM
admet-1317	402	3	(	(	PUNCT
admet-1317	402	4	2015	2015	NUM
admet-1317	402	5	)	)	PUNCT
admet-1317	402	6	276	276	NUM
admet-1317	402	7	-	-	SYM
admet-1317	402	8	285	285	NUM
admet-1317	402	9	.	.	PUNCT
admet-1317	403	1	https://doi.org/10.1039/c4tb01555j	https://doi.org/10.1039/c4tb01555j	PROPN
admet-1317	403	2	.	.	PUNCT
admet-1317	404	1	https://doi.org/10.1016/j.clinthera.2017.01.005	https://doi.org/10.1016/j.clinthera.2017.01.005	PROPN
admet-1317	404	2	https://doi.org/10.1089/thy.2014.0028	https://doi.org/10.1089/thy.2014.0028	PROPN
admet-1317	404	3	https://doi.org/10.1001/jama.1991.03470150090036	https://doi.org/10.1001/jama.1991.03470150090036	PROPN
admet-1317	404	4	https://doi.org/10.1016/j.addr.2003.10.023	https://doi.org/10.1016/j.addr.2003.10.023	NUM
admet-1317	404	5	https://doi.org/10.1073/pnas.2331316100	https://doi.org/10.1073/pnas.2331316100	PROPN
admet-1317	404	6	https://doi.org/10.3390/pharmaceutics7030090	https://doi.org/10.3390/pharmaceutics7030090	PROPN
admet-1317	404	7	https://doi.org/10.1016/j.jconrel.2017.03.383	https://doi.org/10.1016/j.jconrel.2017.03.383	PROPN
admet-1317	404	8	https://doi.org/10.1016/j.jconrel.2017.03.383	https://doi.org/10.1016/j.jconrel.2017.03.383	VERB
admet-1317	404	9	https://doi.org/10.1016/j.biopha.2017.07.019	https://doi.org/10.1016/j.biopha.2017.07.019	PRON
admet-1317	404	10	https://doi.org/10.25258/ijddt.11.2.67	https://doi.org/10.25258/ijddt.11.2.67	PROPN
admet-1317	404	11	https://doi.org/10.1166/jbn.2015.2115	https://doi.org/10.1166/jbn.2015.2115	PROPN
admet-1317	404	12	https://doi.org/10.1166/jbn.2016.2122	https://doi.org/10.1166/jbn.2016.2122	X
admet-1317	404	13	https://doi.org/10.1016/j.msec.2017.05.143	https://doi.org/10.1016/j.msec.2017.05.143	PROPN
admet-1317	404	14	https://doi.org/10.1016/j.addr.2018.03.011	https://doi.org/10.1016/j.addr.2018.03.011	PROPN
admet-1317	404	15	https://doi.org/10.1016/j.ejps.2021.105895	https://doi.org/10.1016/j.ejps.2021.105895	PROPN
admet-1317	404	16	https://doi.org/10.1039/c4tb01555j	https://doi.org/10.1039/c4tb01555j	PROPN
admet-1317	404	17	https://doi.org/10.1039/c4tb01555j	https://doi.org/10.1039/c4tb01555j	PROPN
admet-1317	404	18	admet	admet	X
admet-1317	404	19	&	&	CCONJ
admet-1317	404	20	dmpk	dmpk	PROPN
admet-1317	404	21	10(3	10(3	NUM
admet-1317	404	22	)	)	PUNCT
admet-1317	404	23	(	(	PUNCT
admet-1317	404	24	2022	2022	NUM
admet-1317	404	25	)	)	PUNCT
admet-1317	404	26	213	213	NUM
admet-1317	404	27	-	-	SYM
admet-1317	404	28	230	230	NUM
admet-1317	404	29	transdermal	transdermal	ADJ
admet-1317	404	30	delivery	delivery	NOUN
admet-1317	404	31	of	of	ADP
admet-1317	404	32	levothyroxine	levothyroxine	NOUN
admet-1317	404	33	via	via	ADP
admet-1317	404	34	dissolving	dissolve	VERB
admet-1317	404	35	microneedles	microneedle	NOUN
admet-1317	404	36	doi	doi	PROPN
admet-1317	404	37	:	:	PUNCT
admet-1317	404	38	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	NUM
admet-1317	404	39	229	229	NUM
admet-1317	405	1	[	[	X
admet-1317	405	2	17	17	NUM
admet-1317	405	3	]	]	X
admet-1317	405	4	s.	s.	PROPN
admet-1317	405	5	khan	khan	PROPN
admet-1317	405	6	,	,	PUNCT
admet-1317	405	7	m.u	m.u	PROPN
admet-1317	405	8	.	.	PROPN
admet-1317	405	9	minhas	minhas	PROPN
admet-1317	405	10	,	,	PUNCT
admet-1317	405	11	i.a	i.a	PROPN
admet-1317	405	12	.	.	PROPN
admet-1317	405	13	tekko	tekko	PROPN
admet-1317	405	14	,	,	PUNCT
admet-1317	405	15	r.f	r.f	PROPN
admet-1317	405	16	.	.	PROPN
admet-1317	405	17	donnelly	donnelly	PROPN
admet-1317	405	18	,	,	PUNCT
admet-1317	405	19	r.r.s	r.r.s	PROPN
admet-1317	405	20	.	.	PUNCT
admet-1317	406	1	thakur	thakur	PROPN
admet-1317	406	2	.	.	PUNCT
admet-1317	407	1	evaluation	evaluation	NOUN
admet-1317	407	2	of	of	ADP
admet-1317	407	3	microneedles	microneedle	NOUN
admet-1317	407	4	-	-	PUNCT
admet-1317	407	5	assisted	assist	VERB
admet-1317	407	6	in	in	ADP
admet-1317	407	7	situ	situ	ADJ
admet-1317	407	8	depot	depot	NOUN
admet-1317	407	9	forming	form	VERB
admet-1317	407	10	poloxamer	poloxamer	NOUN
admet-1317	407	11	gels	gel	NOUN
admet-1317	407	12	for	for	ADP
admet-1317	407	13	sustained	sustained	ADJ
admet-1317	407	14	transdermal	transdermal	ADJ
admet-1317	407	15	drug	drug	NOUN
admet-1317	407	16	delivery	delivery	NOUN
admet-1317	407	17	.	.	PUNCT
admet-1317	408	1	drug	drug	NOUN
admet-1317	408	2	deliv	deliv	PROPN
admet-1317	408	3	.	.	PUNCT
admet-1317	409	1	transl	transl	PROPN
admet-1317	409	2	.	.	PUNCT
admet-1317	410	1	res	re	NOUN
admet-1317	410	2	.	.	PROPN
admet-1317	410	3	9	9	NUM
admet-1317	410	4	(	(	PUNCT
admet-1317	410	5	2019	2019	NUM
admet-1317	410	6	)	)	PUNCT
admet-1317	410	7	764	764	NUM
admet-1317	410	8	-	-	SYM
admet-1317	410	9	782	782	NUM
admet-1317	410	10	.	.	PUNCT
admet-1317	411	1	https://doi.org/10.1007/s13346-019-00617-2	https://doi.org/10.1007/s13346-019-00617-2	X
admet-1317	411	2	.	.	PUNCT
admet-1317	412	1	[	[	X
admet-1317	412	2	18	18	NUM
admet-1317	412	3	]	]	X
admet-1317	412	4	e.	e.	PROPN
admet-1317	412	5	larrañeta	larrañeta	PROPN
admet-1317	412	6	,	,	PUNCT
admet-1317	412	7	j.	j.	PROPN
admet-1317	412	8	moore	moore	PROPN
admet-1317	412	9	,	,	PUNCT
admet-1317	412	10	e.m	e.m	PROPN
admet-1317	412	11	.	.	PROPN
admet-1317	412	12	vicente	vicente	PROPN
admet-1317	412	13	-	-	PUNCT
admet-1317	412	14	pérez	pérez	NOUN
admet-1317	412	15	,	,	PUNCT
admet-1317	412	16	p.	p.	PROPN
admet-1317	412	17	gonzález	gonzález	PROPN
admet-1317	412	18	-	-	PUNCT
admet-1317	412	19	vázquez	vázquez	PROPN
admet-1317	412	20	,	,	PUNCT
admet-1317	412	21	r.	r.	PROPN
admet-1317	412	22	lutton	lutton	PROPN
admet-1317	412	23	,	,	PUNCT
admet-1317	412	24	a.d	a.d	PROPN
admet-1317	412	25	.	.	PROPN
admet-1317	412	26	woolfson	woolfson	PROPN
admet-1317	412	27	,	,	PUNCT
admet-1317	412	28	r.f	r.f	PROPN
admet-1317	412	29	.	.	PROPN
admet-1317	412	30	donnelly	donnelly	PROPN
admet-1317	412	31	.	.	PUNCT
admet-1317	413	1	a	a	DET
admet-1317	413	2	proposed	propose	VERB
admet-1317	413	3	model	model	NOUN
admet-1317	413	4	membrane	membrane	NOUN
admet-1317	413	5	and	and	CCONJ
admet-1317	413	6	test	test	NOUN
admet-1317	413	7	method	method	NOUN
admet-1317	413	8	for	for	ADP
admet-1317	413	9	microneedle	microneedle	NOUN
admet-1317	413	10	insertion	insertion	NOUN
admet-1317	413	11	studies	study	NOUN
admet-1317	413	12	.	.	PUNCT
admet-1317	414	1	international	international	ADJ
admet-1317	414	2	journal	journal	PROPN
admet-1317	414	3	of	of	ADP
admet-1317	414	4	pharmaceutics	pharmaceutic	NOUN
admet-1317	414	5	472	472	NUM
admet-1317	414	6	(	(	PUNCT
admet-1317	414	7	2014	2014	NUM
admet-1317	414	8	)	)	PUNCT
admet-1317	414	9	65	65	NUM
admet-1317	414	10	-	-	SYM
admet-1317	414	11	73	73	NUM
admet-1317	414	12	.	.	PUNCT
admet-1317	415	1	https://doi.org/10.1016/j.ijpharm.2014.05.042	https://doi.org/10.1016/j.ijpharm.2014.05.042	NUM
admet-1317	415	2	.	.	PUNCT
admet-1317	416	1	[	[	X
admet-1317	416	2	19	19	NUM
admet-1317	416	3	]	]	X
admet-1317	416	4	c.h	c.h	PROPN
admet-1317	416	5	.	.	PUNCT
admet-1317	416	6	chen	chen	PROPN
admet-1317	416	7	,	,	PUNCT
admet-1317	416	8	v.b	v.b	PROPN
admet-1317	416	9	.	.	PROPN
admet-1317	416	10	shyu	shyu	PROPN
admet-1317	416	11	,	,	PUNCT
admet-1317	416	12	c.t	c.t	PROPN
admet-1317	416	13	.	.	PROPN
admet-1317	416	14	chen	chen	PROPN
admet-1317	416	15	.	.	PUNCT
admet-1317	417	1	dissolving	dissolve	VERB
admet-1317	417	2	microneedle	microneedle	NOUN
admet-1317	417	3	patches	patch	NOUN
admet-1317	417	4	for	for	ADP
admet-1317	417	5	transdermal	transdermal	ADJ
admet-1317	417	6	insulin	insulin	NOUN
admet-1317	417	7	delivery	delivery	NOUN
admet-1317	417	8	in	in	ADP
admet-1317	417	9	diabetic	diabetic	ADJ
admet-1317	417	10	mice	mouse	NOUN
admet-1317	417	11	:	:	PUNCT
admet-1317	417	12	potential	potential	ADJ
admet-1317	417	13	for	for	ADP
admet-1317	417	14	clinical	clinical	ADJ
admet-1317	417	15	applications	application	NOUN
admet-1317	417	16	.	.	PUNCT
admet-1317	418	1	materials	material	NOUN
admet-1317	418	2	(	(	PUNCT
admet-1317	418	3	basel	basel	PROPN
admet-1317	418	4	)	)	PUNCT
admet-1317	418	5	11	11	NUM
admet-1317	418	6	(	(	PUNCT
admet-1317	418	7	2018	2018	NUM
admet-1317	418	8	)	)	PUNCT
admet-1317	418	9	1625	1625	NUM
admet-1317	418	10	.	.	PUNCT
admet-1317	419	1	https://doi.org/10.3390/ma11091625	https://doi.org/10.3390/ma11091625	NOUN
admet-1317	419	2	.	.	PUNCT
admet-1317	420	1	[	[	X
admet-1317	420	2	20	20	NUM
admet-1317	420	3	]	]	PUNCT
admet-1317	420	4	s.	s.	PROPN
admet-1317	420	5	liu	liu	PROPN
admet-1317	420	6	,	,	PUNCT
admet-1317	420	7	m.-n	m.-n	PROPN
admet-1317	420	8	.	.	PUNCT
admet-1317	421	1	jin	jin	PROPN
admet-1317	421	2	,	,	PUNCT
admet-1317	421	3	y.-s	y.-	NOUN
admet-1317	421	4	.	.	PUNCT
admet-1317	422	1	quan	quan	PROPN
admet-1317	422	2	,	,	PUNCT
admet-1317	422	3	f.	f.	PROPN
admet-1317	422	4	kamiyama	kamiyama	PROPN
admet-1317	422	5	,	,	PUNCT
admet-1317	422	6	h.	h.	PROPN
admet-1317	422	7	katsumi	katsumi	PROPN
admet-1317	422	8	,	,	PUNCT
admet-1317	422	9	t.	t.	PROPN
admet-1317	422	10	sakane	sakane	PROPN
admet-1317	422	11	,	,	PUNCT
admet-1317	422	12	a.	a.	PROPN
admet-1317	422	13	yamamoto	yamamoto	PROPN
admet-1317	422	14	.	.	PUNCT
admet-1317	423	1	the	the	DET
admet-1317	423	2	development	development	NOUN
admet-1317	423	3	and	and	CCONJ
admet-1317	423	4	characteristics	characteristic	NOUN
admet-1317	423	5	of	of	ADP
admet-1317	423	6	novel	novel	NOUN
admet-1317	423	7	microneedle	microneedle	NOUN
admet-1317	423	8	arrays	array	NOUN
admet-1317	423	9	fabricated	fabricate	VERB
admet-1317	423	10	from	from	ADP
admet-1317	423	11	hyaluronic	hyaluronic	ADJ
admet-1317	423	12	acid	acid	NOUN
admet-1317	423	13	,	,	PUNCT
admet-1317	423	14	and	and	CCONJ
admet-1317	423	15	their	their	PRON
admet-1317	423	16	application	application	NOUN
admet-1317	423	17	in	in	ADP
admet-1317	423	18	the	the	DET
admet-1317	423	19	transdermal	transdermal	ADJ
admet-1317	423	20	delivery	delivery	NOUN
admet-1317	423	21	of	of	ADP
admet-1317	423	22	insulin	insulin	NOUN
admet-1317	423	23	.	.	PUNCT
admet-1317	424	1	journal	journal	PROPN
admet-1317	424	2	of	of	ADP
admet-1317	424	3	controlled	control	VERB
admet-1317	424	4	release	release	NOUN
admet-1317	424	5	161	161	NUM
admet-1317	424	6	(	(	PUNCT
admet-1317	424	7	2012	2012	NUM
admet-1317	424	8	)	)	PUNCT
admet-1317	424	9	933	933	NUM
admet-1317	424	10	-	-	SYM
admet-1317	424	11	941	941	NUM
admet-1317	424	12	.	.	PUNCT
admet-1317	425	1	https://doi.org/10.1016/j.jconrel.2012.05.030	https://doi.org/10.1016/j.jconrel.2012.05.030	X
admet-1317	425	2	.	.	PUNCT
admet-1317	426	1	[	[	X
admet-1317	426	2	21	21	NUM
admet-1317	426	3	]	]	X
admet-1317	426	4	m.	m.	NOUN
admet-1317	426	5	mir	mir	PROPN
admet-1317	426	6	,	,	PUNCT
admet-1317	426	7	a.d	a.d	PROPN
admet-1317	426	8	.	.	PROPN
admet-1317	426	9	permana	permana	PROPN
admet-1317	426	10	,	,	PUNCT
admet-1317	426	11	n.	n.	PROPN
admet-1317	426	12	ahmed	ahmed	PROPN
admet-1317	426	13	,	,	PUNCT
admet-1317	426	14	g.m	g.m	PROPN
admet-1317	426	15	.	.	PROPN
admet-1317	426	16	khan	khan	PROPN
admet-1317	426	17	,	,	PUNCT
admet-1317	426	18	a.	a.	PROPN
admet-1317	426	19	ur	ur	PROPN
admet-1317	426	20	rehman	rehman	PROPN
admet-1317	426	21	,	,	PUNCT
admet-1317	426	22	r.f	r.f	PROPN
admet-1317	426	23	.	.	PROPN
admet-1317	426	24	donnelly	donnelly	PROPN
admet-1317	426	25	.	.	PUNCT
admet-1317	426	26	enhancement	enhancement	NOUN
admet-1317	426	27	in	in	ADP
admet-1317	426	28	sitespecific	sitespecific	ADJ
admet-1317	426	29	delivery	delivery	NOUN
admet-1317	426	30	of	of	ADP
admet-1317	426	31	carvacrol	carvacrol	NOUN
admet-1317	426	32	for	for	ADP
admet-1317	426	33	potential	potential	ADJ
admet-1317	426	34	treatment	treatment	NOUN
admet-1317	426	35	of	of	ADP
admet-1317	426	36	infected	infected	ADJ
admet-1317	426	37	wounds	wound	NOUN
admet-1317	426	38	using	use	VERB
admet-1317	426	39	infection	infection	NOUN
admet-1317	426	40	responsive	responsive	ADJ
admet-1317	426	41	nanoparticles	nanoparticle	NOUN
admet-1317	426	42	loaded	load	VERB
admet-1317	426	43	into	into	ADP
admet-1317	426	44	dissolving	dissolve	VERB
admet-1317	426	45	microneedles	microneedle	NOUN
admet-1317	426	46	:	:	PUNCT
admet-1317	426	47	a	a	DET
admet-1317	426	48	proof	proof	NOUN
admet-1317	426	49	of	of	ADP
admet-1317	426	50	concept	concept	NOUN
admet-1317	426	51	study	study	NOUN
admet-1317	426	52	.	.	PUNCT
admet-1317	427	1	european	european	PROPN
admet-1317	427	2	journal	journal	PROPN
admet-1317	427	3	of	of	ADP
admet-1317	427	4	pharmaceutics	pharmaceutic	NOUN
admet-1317	427	5	and	and	CCONJ
admet-1317	427	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1317	427	7	147	147	NUM
admet-1317	427	8	(	(	PUNCT
admet-1317	427	9	2020	2020	NUM
admet-1317	427	10	)	)	PUNCT
admet-1317	427	11	57	57	NUM
admet-1317	427	12	-	-	SYM
admet-1317	427	13	68	68	NUM
admet-1317	427	14	.	.	PUNCT
admet-1317	428	1	https://doi.org/10.1016/j.ejpb.2019.12.008	https://doi.org/10.1016/j.ejpb.2019.12.008	NOUN
admet-1317	428	2	.	.	PUNCT
admet-1317	429	1	[	[	X
admet-1317	429	2	22	22	NUM
admet-1317	429	3	]	]	X
admet-1317	429	4	h.x	h.x	PROPN
admet-1317	429	5	.	.	PROPN
admet-1317	429	6	nguyen	nguyen	PROPN
admet-1317	429	7	,	,	PUNCT
admet-1317	429	8	b.d	b.d	PROPN
admet-1317	429	9	.	.	PROPN
admet-1317	429	10	bozorg	bozorg	PROPN
admet-1317	429	11	,	,	PUNCT
admet-1317	429	12	y.	y.	PROPN
admet-1317	429	13	kim	kim	PROPN
admet-1317	429	14	,	,	PUNCT
admet-1317	429	15	a.	a.	PROPN
admet-1317	429	16	wieber	wieber	PROPN
admet-1317	429	17	,	,	PUNCT
admet-1317	429	18	g.	g.	PROPN
admet-1317	429	19	birk	birk	PROPN
admet-1317	429	20	,	,	PUNCT
admet-1317	429	21	d.	d.	PROPN
admet-1317	429	22	lubda	lubda	PROPN
admet-1317	429	23	,	,	PUNCT
admet-1317	429	24	a.k	a.k	PROPN
admet-1317	429	25	.	.	PROPN
admet-1317	429	26	banga	banga	PROPN
admet-1317	429	27	.	.	PUNCT
admet-1317	430	1	poly	poly	ADJ
admet-1317	430	2	(	(	PUNCT
admet-1317	430	3	vinyl	vinyl	NOUN
admet-1317	430	4	alcohol	alcohol	NOUN
admet-1317	430	5	)	)	PUNCT
admet-1317	430	6	microneedles	microneedle	NOUN
admet-1317	430	7	:	:	PUNCT
admet-1317	430	8	fabrication	fabrication	NOUN
admet-1317	430	9	,	,	PUNCT
admet-1317	430	10	characterization	characterization	NOUN
admet-1317	430	11	,	,	PUNCT
admet-1317	430	12	and	and	CCONJ
admet-1317	430	13	application	application	NOUN
admet-1317	430	14	for	for	ADP
admet-1317	430	15	transdermal	transdermal	ADJ
admet-1317	430	16	drug	drug	NOUN
admet-1317	430	17	delivery	delivery	NOUN
admet-1317	430	18	of	of	ADP
admet-1317	430	19	doxorubicin	doxorubicin	PROPN
admet-1317	430	20	.	.	PUNCT
admet-1317	431	1	eur	eur	PROPN
admet-1317	431	2	.	.	PUNCT
admet-1317	432	1	j.	j.	PROPN
admet-1317	432	2	pharm	pharm	PROPN
admet-1317	432	3	biopharm	biopharm	PROPN
admet-1317	432	4	129	129	NUM
admet-1317	432	5	(	(	PUNCT
admet-1317	432	6	2018	2018	NUM
admet-1317	432	7	)	)	PUNCT
admet-1317	432	8	88	88	NUM
admet-1317	432	9	-	-	SYM
admet-1317	432	10	103	103	NUM
admet-1317	432	11	.	.	PUNCT
admet-1317	433	1	https://doi.org/10.1016/j.ejpb.2018.05.017	https://doi.org/10.1016/j.ejpb.2018.05.017	NOUN
admet-1317	433	2	.	.	PUNCT
admet-1317	434	1	[	[	X
admet-1317	434	2	23	23	NUM
admet-1317	434	3	]	]	X
admet-1317	434	4	m.s	m.s	PROPN
admet-1317	434	5	.	.	PROPN
admet-1317	435	1	lhernould	lhernould	AUX
admet-1317	435	2	,	,	PUNCT
admet-1317	435	3	m.	m.	NOUN
admet-1317	435	4	deleers	deleer	NOUN
admet-1317	435	5	,	,	PUNCT
admet-1317	435	6	a.	a.	NOUN
admet-1317	435	7	delchambre	delchambre	NOUN
admet-1317	435	8	.	.	PUNCT
admet-1317	436	1	hollow	hollow	ADJ
admet-1317	436	2	polymer	polymer	NOUN
admet-1317	436	3	microneedles	microneedle	NOUN
admet-1317	436	4	array	array	VERB
admet-1317	436	5	resistance	resistance	NOUN
admet-1317	436	6	and	and	CCONJ
admet-1317	436	7	insertion	insertion	NOUN
admet-1317	436	8	tests	test	NOUN
admet-1317	436	9	.	.	PUNCT
admet-1317	437	1	int	int	NOUN
admet-1317	437	2	.	.	PUNCT
admet-1317	438	1	j.	j.	PROPN
admet-1317	438	2	pharm	pharm	PROPN
admet-1317	438	3	.	.	PUNCT
admet-1317	439	1	480	480	NUM
admet-1317	439	2	(	(	PUNCT
admet-1317	439	3	2015	2015	NUM
admet-1317	439	4	)	)	PUNCT
admet-1317	439	5	152	152	NUM
admet-1317	439	6	-	-	SYM
admet-1317	439	7	157	157	NUM
admet-1317	439	8	.	.	PUNCT
admet-1317	440	1	https://doi.org/10.1016/j.ijpharm.2015.01.019	https://doi.org/10.1016/j.ijpharm.2015.01.019	PROPN
admet-1317	440	2	.	.	PUNCT
admet-1317	441	1	[	[	X
admet-1317	441	2	24	24	NUM
admet-1317	441	3	]	]	X
admet-1317	441	4	m.j	m.j	PROPN
admet-1317	441	5	.	.	PROPN
admet-1317	441	6	kim	kim	PROPN
admet-1317	441	7	,	,	PUNCT
admet-1317	441	8	s.c	s.c	PROPN
admet-1317	441	9	.	.	PROPN
admet-1317	441	10	park	park	PROPN
admet-1317	441	11	,	,	PUNCT
admet-1317	441	12	s.-o	s.-o	PROPN
admet-1317	441	13	.	.	PUNCT
admet-1317	442	1	choi	choi	NOUN
admet-1317	442	2	.	.	PUNCT
admet-1317	443	1	dual	dual	ADJ
admet-1317	443	2	-	-	PUNCT
admet-1317	443	3	nozzle	nozzle	NOUN
admet-1317	443	4	spray	spray	NOUN
admet-1317	443	5	deposition	deposition	NOUN
admet-1317	443	6	process	process	NOUN
admet-1317	443	7	for	for	ADP
admet-1317	443	8	improving	improve	VERB
admet-1317	443	9	the	the	DET
admet-1317	443	10	stability	stability	NOUN
admet-1317	443	11	of	of	ADP
admet-1317	443	12	proteins	protein	NOUN
admet-1317	443	13	in	in	ADP
admet-1317	443	14	polymer	polymer	NOUN
admet-1317	443	15	microneedles	microneedle	NOUN
admet-1317	443	16	.	.	PUNCT
admet-1317	444	1	rsc	rsc	PROPN
admet-1317	444	2	advances	advance	VERB
admet-1317	444	3	7	7	NUM
admet-1317	444	4	(	(	PUNCT
admet-1317	444	5	2017	2017	NUM
admet-1317	444	6	)	)	PUNCT
admet-1317	444	7	55350	55350	NUM
admet-1317	444	8	-	-	SYM
admet-1317	444	9	55359	55359	NUM
admet-1317	444	10	.	.	PUNCT
admet-1317	445	1	https://doi.org/10.1039/c7ra10928h	https://doi.org/10.1039/c7ra10928h	NUM
admet-1317	445	2	.	.	PUNCT
admet-1317	446	1	[	[	X
admet-1317	446	2	25	25	NUM
admet-1317	446	3	]	]	X
admet-1317	446	4	h.	h.	PROPN
admet-1317	446	5	du	du	PROPN
admet-1317	446	6	,	,	PUNCT
admet-1317	446	7	p.	p.	PROPN
admet-1317	446	8	liu	liu	PROPN
admet-1317	446	9	,	,	PUNCT
admet-1317	446	10	j.	j.	PROPN
admet-1317	446	11	zhu	zhu	PROPN
admet-1317	446	12	,	,	PUNCT
admet-1317	446	13	j.	j.	PROPN
admet-1317	446	14	lan	lan	PROPN
admet-1317	446	15	,	,	PUNCT
admet-1317	446	16	y.	y.	PROPN
admet-1317	446	17	li	li	PROPN
admet-1317	446	18	,	,	PUNCT
admet-1317	446	19	l.	l.	PROPN
admet-1317	446	20	zhang	zhang	PROPN
admet-1317	446	21	,	,	PUNCT
admet-1317	446	22	j.	j.	PROPN
admet-1317	446	23	zhu	zhu	PROPN
admet-1317	446	24	,	,	PUNCT
admet-1317	446	25	j.	j.	PROPN
admet-1317	446	26	tao	tao	PROPN
admet-1317	446	27	.	.	PUNCT
admet-1317	446	28	hyaluronic	hyaluronic	ADJ
admet-1317	446	29	acid	acid	NOUN
admet-1317	446	30	-	-	PUNCT
admet-1317	446	31	based	base	VERB
admet-1317	446	32	dissolving	dissolving	NOUN
admet-1317	446	33	microneedle	microneedle	NOUN
admet-1317	446	34	patch	patch	NOUN
admet-1317	446	35	loaded	load	VERB
admet-1317	446	36	with	with	ADP
admet-1317	446	37	methotrexate	methotrexate	NOUN
admet-1317	446	38	for	for	ADP
admet-1317	446	39	improved	improved	ADJ
admet-1317	446	40	treatment	treatment	NOUN
admet-1317	446	41	of	of	ADP
admet-1317	446	42	psoriasis	psoriasis	NOUN
admet-1317	446	43	.	.	PUNCT
admet-1317	447	1	acs	acs	PROPN
admet-1317	447	2	appl	appl	PROPN
admet-1317	447	3	.	.	PUNCT
admet-1317	448	1	mater	mater	PROPN
admet-1317	448	2	.	.	PUNCT
admet-1317	449	1	interfaces	interface	NOUN
admet-1317	449	2	11	11	NUM
admet-1317	449	3	(	(	PUNCT
admet-1317	449	4	2019	2019	NUM
admet-1317	449	5	)	)	PUNCT
admet-1317	449	6	43588	43588	NUM
admet-1317	449	7	-	-	SYM
admet-1317	449	8	43598	43598	NUM
admet-1317	449	9	.	.	PUNCT
admet-1317	450	1	https://doi.org/10.1021/acsami.9b15668	https://doi.org/10.1021/acsami.9b15668	NOUN
admet-1317	450	2	.	.	PUNCT
admet-1317	451	1	[	[	X
admet-1317	451	2	26	26	NUM
admet-1317	451	3	]	]	X
admet-1317	451	4	g.	g.	PROPN
admet-1317	451	5	yao	yao	PROPN
admet-1317	451	6	,	,	PUNCT
admet-1317	451	7	g.	g.	PROPN
admet-1317	451	8	quan	quan	PROPN
admet-1317	451	9	,	,	PUNCT
admet-1317	451	10	s.	s.	PROPN
admet-1317	451	11	lin	lin	PROPN
admet-1317	451	12	,	,	PUNCT
admet-1317	451	13	t.	t.	PROPN
admet-1317	451	14	peng	peng	PROPN
admet-1317	451	15	,	,	PUNCT
admet-1317	451	16	q.	q.	PROPN
admet-1317	451	17	wang	wang	PROPN
admet-1317	451	18	,	,	PUNCT
admet-1317	451	19	h.	h.	PROPN
admet-1317	451	20	ran	run	VERB
admet-1317	451	21	,	,	PUNCT
admet-1317	451	22	h.	h.	PROPN
admet-1317	451	23	chen	chen	PROPN
admet-1317	451	24	,	,	PUNCT
admet-1317	451	25	q.	q.	PROPN
admet-1317	451	26	zhang	zhang	PROPN
admet-1317	451	27	,	,	PUNCT
admet-1317	451	28	l.	l.	PROPN
admet-1317	451	29	wang	wang	PROPN
admet-1317	451	30	,	,	PUNCT
admet-1317	451	31	x.	x.	PROPN
admet-1317	451	32	pan	pan	PROPN
admet-1317	451	33	,	,	PUNCT
admet-1317	451	34	c.	c.	PROPN
admet-1317	451	35	wu	wu	PROPN
admet-1317	451	36	.	.	PUNCT
admet-1317	452	1	novel	novel	NOUN
admet-1317	452	2	dissolving	dissolve	VERB
admet-1317	452	3	microneedles	microneedle	NOUN
admet-1317	452	4	for	for	ADP
admet-1317	452	5	enhanced	enhanced	ADJ
admet-1317	452	6	transdermal	transdermal	ADJ
admet-1317	452	7	delivery	delivery	NOUN
admet-1317	452	8	of	of	ADP
admet-1317	452	9	levonorgestrel	levonorgestrel	NOUN
admet-1317	452	10	:	:	PUNCT
admet-1317	452	11	in	in	ADP
admet-1317	452	12	vitro	vitro	X
admet-1317	452	13	and	and	CCONJ
admet-1317	452	14	in	in	ADP
admet-1317	452	15	vivo	vivo	ADJ
admet-1317	452	16	characterization	characterization	NOUN
admet-1317	452	17	.	.	PUNCT
admet-1317	453	1	int	int	NOUN
admet-1317	453	2	.	.	PUNCT
admet-1317	454	1	j.	j.	PROPN
admet-1317	454	2	pharm	pharm	PROPN
admet-1317	454	3	.	.	PUNCT
admet-1317	455	1	534	534	NUM
admet-1317	455	2	(	(	PUNCT
admet-1317	455	3	2017	2017	NUM
admet-1317	455	4	)	)	PUNCT
admet-1317	455	5	378	378	NUM
admet-1317	455	6	-	-	SYM
admet-1317	455	7	386	386	NUM
admet-1317	455	8	.	.	PUNCT
admet-1317	455	9	https://doi.org/10.1016/j.ijpharm.2017.10.035	https://doi.org/10.1016/j.ijpharm.2017.10.035	NOUN
admet-1317	455	10	.	.	PUNCT
admet-1317	456	1	[	[	X
admet-1317	456	2	27	27	NUM
admet-1317	456	3	]	]	PUNCT
admet-1317	456	4	s.	s.	PROPN
admet-1317	456	5	liu	liu	PROPN
admet-1317	456	6	,	,	PUNCT
admet-1317	456	7	m.-n	m.-n	PROPN
admet-1317	456	8	.	.	PUNCT
admet-1317	457	1	jin	jin	PROPN
admet-1317	457	2	,	,	PUNCT
admet-1317	457	3	y.-s	y.-	NOUN
admet-1317	457	4	.	.	PUNCT
admet-1317	458	1	quan	quan	PROPN
admet-1317	458	2	,	,	PUNCT
admet-1317	458	3	f.	f.	PROPN
admet-1317	458	4	kamiyama	kamiyama	PROPN
admet-1317	458	5	,	,	PUNCT
admet-1317	458	6	k.	k.	PROPN
admet-1317	458	7	kusamori	kusamori	PROPN
admet-1317	458	8	,	,	PUNCT
admet-1317	458	9	h.	h.	PROPN
admet-1317	458	10	katsumi	katsumi	PROPN
admet-1317	458	11	,	,	PUNCT
admet-1317	458	12	t.	t.	PROPN
admet-1317	458	13	sakane	sakane	PROPN
admet-1317	458	14	,	,	PUNCT
admet-1317	458	15	a.	a.	PROPN
admet-1317	458	16	yamamoto	yamamoto	PROPN
admet-1317	458	17	.	.	PUNCT
admet-1317	459	1	transdermal	transdermal	ADJ
admet-1317	459	2	delivery	delivery	NOUN
admet-1317	459	3	of	of	ADP
admet-1317	459	4	relatively	relatively	ADV
admet-1317	459	5	high	high	ADJ
admet-1317	459	6	molecular	molecular	ADJ
admet-1317	459	7	weight	weight	NOUN
admet-1317	459	8	drugs	drug	NOUN
admet-1317	459	9	using	use	VERB
admet-1317	459	10	novel	novel	ADJ
admet-1317	459	11	self	self	NOUN
admet-1317	459	12	-	-	PUNCT
admet-1317	459	13	dissolving	dissolve	VERB
admet-1317	459	14	microneedle	microneedle	NOUN
admet-1317	459	15	arrays	array	NOUN
admet-1317	459	16	fabricated	fabricate	VERB
admet-1317	459	17	from	from	ADP
admet-1317	459	18	hyaluronic	hyaluronic	ADJ
admet-1317	459	19	acid	acid	NOUN
admet-1317	459	20	and	and	CCONJ
admet-1317	459	21	their	their	PRON
admet-1317	459	22	characteristics	characteristic	NOUN
admet-1317	459	23	and	and	CCONJ
admet-1317	459	24	safety	safety	NOUN
admet-1317	459	25	after	after	ADP
admet-1317	459	26	application	application	NOUN
admet-1317	459	27	to	to	ADP
admet-1317	459	28	the	the	DET
admet-1317	459	29	skin	skin	NOUN
admet-1317	459	30	.	.	PUNCT
admet-1317	460	1	european	european	ADJ
admet-1317	460	2	journal	journal	PROPN
admet-1317	460	3	of	of	ADP
admet-1317	460	4	pharmaceutics	pharmaceutic	NOUN
admet-1317	460	5	and	and	CCONJ
admet-1317	460	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1317	460	7	86	86	NUM
admet-1317	460	8	(	(	PUNCT
admet-1317	460	9	2014	2014	NUM
admet-1317	460	10	)	)	PUNCT
admet-1317	460	11	267	267	NUM
admet-1317	460	12	-	-	SYM
admet-1317	460	13	276	276	NUM
admet-1317	460	14	.	.	PUNCT
admet-1317	461	1	https://doi.org/10.1016/j.ejpb.2013.10.001	https://doi.org/10.1016/j.ejpb.2013.10.001	NOUN
admet-1317	461	2	.	.	PUNCT
admet-1317	462	1	[	[	X
admet-1317	462	2	28	28	NUM
admet-1317	462	3	]	]	X
admet-1317	462	4	b.	b.	PROPN
admet-1317	462	5	saha	saha	PROPN
admet-1317	462	6	,	,	PUNCT
admet-1317	462	7	w.q	w.q	PROPN
admet-1317	462	8	.	.	PUNCT
admet-1317	462	9	toh	toh	PROPN
admet-1317	462	10	,	,	PUNCT
admet-1317	462	11	e.	e.	PROPN
admet-1317	462	12	liu	liu	PROPN
admet-1317	462	13	,	,	PUNCT
admet-1317	462	14	s.b	s.b	PROPN
admet-1317	462	15	.	.	PROPN
admet-1317	462	16	tor	tor	PROPN
admet-1317	462	17	,	,	PUNCT
admet-1317	462	18	d.e	d.e	PROPN
admet-1317	462	19	.	.	PUNCT
admet-1317	462	20	hardt	hardt	PROPN
admet-1317	462	21	,	,	PUNCT
admet-1317	462	22	j.	j.	PROPN
admet-1317	462	23	lee	lee	PROPN
admet-1317	462	24	.	.	PUNCT
admet-1317	463	1	a	a	DET
admet-1317	463	2	review	review	NOUN
admet-1317	463	3	on	on	ADP
admet-1317	463	4	the	the	DET
admet-1317	463	5	importance	importance	NOUN
admet-1317	463	6	of	of	ADP
admet-1317	463	7	surface	surface	NOUN
admet-1317	463	8	coating	coating	NOUN
admet-1317	463	9	of	of	ADP
admet-1317	463	10	micro	micro	ADJ
admet-1317	463	11	/	/	NOUN
admet-1317	463	12	nano	nano	NOUN
admet-1317	463	13	-	-	PUNCT
admet-1317	463	14	mold	mold	NOUN
admet-1317	463	15	in	in	ADP
admet-1317	463	16	micro	micro	NOUN
admet-1317	463	17	/	/	SYM
admet-1317	463	18	nano	nano	NOUN
admet-1317	463	19	-	-	PUNCT
admet-1317	463	20	molding	mold	VERB
admet-1317	463	21	processes	process	NOUN
admet-1317	463	22	.	.	PUNCT
admet-1317	464	1	journal	journal	PROPN
admet-1317	464	2	of	of	ADP
admet-1317	464	3	micromechanics	micromechanic	NOUN
admet-1317	464	4	and	and	CCONJ
admet-1317	464	5	microengineering	microengineere	VERB
admet-1317	464	6	26	26	NUM
admet-1317	464	7	(	(	PUNCT
admet-1317	464	8	2015	2015	NUM
admet-1317	464	9	)	)	PUNCT
admet-1317	464	10	013002	013002	NUM
admet-1317	464	11	.	.	PUNCT
admet-1317	465	1	https://doi.org/10.1088/0960-1317/26/1/013002	https://doi.org/10.1088/0960-1317/26/1/013002	NOUN
admet-1317	465	2	.	.	PUNCT
admet-1317	466	1	[	[	X
admet-1317	466	2	29	29	NUM
admet-1317	466	3	]	]	X
admet-1317	466	4	s.d	s.d	PROPN
admet-1317	466	5	.	.	PROPN
admet-1317	466	6	gittard	gittard	PROPN
admet-1317	466	7	,	,	PUNCT
admet-1317	466	8	a.	a.	NOUN
admet-1317	466	9	ovsianikov	ovsianikov	PROPN
admet-1317	466	10	,	,	PUNCT
admet-1317	466	11	b.n	b.n	PROPN
admet-1317	466	12	.	.	PROPN
admet-1317	466	13	chichkov	chichkov	PROPN
admet-1317	466	14	,	,	PUNCT
admet-1317	466	15	a.	a.	NOUN
admet-1317	466	16	doraiswamy	doraiswamy	PROPN
admet-1317	466	17	,	,	PUNCT
admet-1317	466	18	r.j	r.j	PROPN
admet-1317	466	19	.	.	PROPN
admet-1317	466	20	narayan	narayan	PROPN
admet-1317	466	21	.	.	PUNCT
admet-1317	466	22	two	two	NUM
admet-1317	466	23	-	-	PUNCT
admet-1317	466	24	photon	photon	NOUN
admet-1317	466	25	polymerization	polymerization	NOUN
admet-1317	466	26	of	of	ADP
admet-1317	466	27	microneedles	microneedle	NOUN
admet-1317	466	28	for	for	ADP
admet-1317	466	29	transdermal	transdermal	ADJ
admet-1317	466	30	drug	drug	NOUN
admet-1317	466	31	delivery	delivery	NOUN
admet-1317	466	32	.	.	PUNCT
admet-1317	467	1	expert	expert	NOUN
admet-1317	467	2	opin	opin	NOUN
admet-1317	467	3	.	.	PUNCT
admet-1317	468	1	drug	drug	NOUN
admet-1317	468	2	deliv	deliv	NOUN
admet-1317	468	3	.	.	PUNCT
admet-1317	469	1	7	7	NUM
admet-1317	469	2	(	(	PUNCT
admet-1317	469	3	2010	2010	NUM
admet-1317	469	4	)	)	PUNCT
admet-1317	469	5	513	513	NUM
admet-1317	469	6	-	-	SYM
admet-1317	469	7	533	533	NUM
admet-1317	469	8	.	.	PUNCT
admet-1317	469	9	https://doi.org/10.1517/17425241003628171	https://doi.org/10.1517/17425241003628171	NOUN
admet-1317	469	10	.	.	PUNCT
admet-1317	470	1	[	[	X
admet-1317	470	2	30	30	NUM
admet-1317	470	3	]	]	X
admet-1317	470	4	s.m	s.m	PROPN
admet-1317	470	5	.	.	PUNCT
admet-1317	470	6	bal	bal	PROPN
admet-1317	470	7	,	,	PUNCT
admet-1317	470	8	a.c	a.c	PROPN
admet-1317	470	9	.	.	PROPN
admet-1317	470	10	kruithof	kruithof	PROPN
admet-1317	470	11	,	,	PUNCT
admet-1317	470	12	r.	r.	PROPN
admet-1317	470	13	zwier	zwier	PROPN
admet-1317	470	14	,	,	PUNCT
admet-1317	470	15	e.	e.	PROPN
admet-1317	470	16	dietz	dietz	PROPN
admet-1317	470	17	,	,	PUNCT
admet-1317	470	18	j.a	j.a	PROPN
admet-1317	470	19	.	.	PROPN
admet-1317	470	20	bouwstra	bouwstra	PROPN
admet-1317	470	21	,	,	PUNCT
admet-1317	470	22	j.	j.	PROPN
admet-1317	470	23	lademann	lademann	PROPN
admet-1317	470	24	,	,	PUNCT
admet-1317	470	25	m.c	m.c	PROPN
admet-1317	470	26	.	.	PROPN
admet-1317	470	27	meinke	meinke	PROPN
admet-1317	470	28	.	.	PUNCT
admet-1317	471	1	influence	influence	NOUN
admet-1317	471	2	of	of	ADP
admet-1317	471	3	microneedle	microneedle	ADJ
admet-1317	471	4	shape	shape	NOUN
admet-1317	471	5	on	on	ADP
admet-1317	471	6	the	the	DET
admet-1317	471	7	transport	transport	NOUN
admet-1317	471	8	of	of	ADP
admet-1317	471	9	a	a	DET
admet-1317	471	10	fluorescent	fluorescent	ADJ
admet-1317	471	11	dye	dye	NOUN
admet-1317	471	12	into	into	ADP
admet-1317	471	13	human	human	ADJ
admet-1317	471	14	skin	skin	NOUN
admet-1317	471	15	in	in	ADP
admet-1317	471	16	vivo	vivo	NOUN
admet-1317	471	17	.	.	PUNCT
admet-1317	472	1	journal	journal	PROPN
admet-1317	472	2	of	of	ADP
admet-1317	472	3	controlled	control	VERB
admet-1317	472	4	release	release	NOUN
admet-1317	472	5	147	147	NUM
admet-1317	472	6	(	(	PUNCT
admet-1317	472	7	2010	2010	NUM
admet-1317	472	8	)	)	PUNCT
admet-1317	472	9	218	218	NUM
admet-1317	472	10	-	-	SYM
admet-1317	472	11	224	224	NUM
admet-1317	472	12	.	.	PUNCT
admet-1317	473	1	https://doi.org/10.1016/j.jconrel.2010.07.104	https://doi.org/10.1016/j.jconrel.2010.07.104	NOUN
admet-1317	473	2	.	.	PUNCT
admet-1317	474	1	[	[	X
admet-1317	474	2	31	31	NUM
admet-1317	474	3	]	]	PUNCT
admet-1317	474	4	s.	s.	PROPN
admet-1317	474	5	lau	lau	PROPN
admet-1317	474	6	,	,	PUNCT
admet-1317	474	7	j.	j.	PROPN
admet-1317	474	8	fei	fei	PROPN
admet-1317	474	9	,	,	PUNCT
admet-1317	474	10	h.	h.	PROPN
admet-1317	474	11	liu	liu	PROPN
admet-1317	474	12	,	,	PUNCT
admet-1317	474	13	w.	w.	PROPN
admet-1317	474	14	chen	chen	PROPN
admet-1317	474	15	,	,	PUNCT
admet-1317	474	16	r.	r.	PROPN
admet-1317	474	17	liu	liu	PROPN
admet-1317	474	18	.	.	PROPN
admet-1317	474	19	multilayered	multilayere	VERB
admet-1317	474	20	pyramidal	pyramidal	ADJ
admet-1317	474	21	dissolving	dissolve	VERB
admet-1317	474	22	microneedle	microneedle	NOUN
admet-1317	474	23	patches	patch	NOUN
admet-1317	474	24	with	with	ADP
admet-1317	474	25	flexible	flexible	ADJ
admet-1317	474	26	pedestals	pedestal	NOUN
admet-1317	474	27	for	for	ADP
admet-1317	474	28	improving	improve	VERB
admet-1317	474	29	effective	effective	ADJ
admet-1317	474	30	drug	drug	NOUN
admet-1317	474	31	delivery	delivery	NOUN
admet-1317	474	32	.	.	PUNCT
admet-1317	475	1	j.	j.	PROPN
admet-1317	475	2	control	control	PROPN
admet-1317	475	3	.	.	PUNCT
admet-1317	476	1	release	release	VERB
admet-1317	476	2	265	265	NUM
admet-1317	476	3	(	(	PUNCT
admet-1317	476	4	2017	2017	NUM
admet-1317	476	5	)	)	PUNCT
admet-1317	476	6	113	113	NUM
admet-1317	476	7	-	-	SYM
admet-1317	476	8	119	119	NUM
admet-1317	476	9	.	.	PUNCT
admet-1317	477	1	https://doi.org/10.1016/j.jconrel.2016.08.031	https://doi.org/10.1016/j.jconrel.2016.08.031	PROPN
admet-1317	477	2	.	.	PUNCT
admet-1317	478	1	http://dx.doi.org/10.5599/admet.1317	http://dx.doi.org/10.5599/admet.1317	PROPN
admet-1317	478	2	https://doi.org/10.1007/s13346-019-00617-2	https://doi.org/10.1007/s13346-019-00617-2	NUM
admet-1317	478	3	https://doi.org/10.1016/j.ijpharm.2014.05.042	https://doi.org/10.1016/j.ijpharm.2014.05.042	NUM
admet-1317	478	4	https://doi.org/10.1016/j.ijpharm.2014.05.042	https://doi.org/10.1016/j.ijpharm.2014.05.042	NUM
admet-1317	478	5	https://doi.org/10.3390/ma11091625	https://doi.org/10.3390/ma11091625	NUM
admet-1317	478	6	https://doi.org/10.3390/ma11091625	https://doi.org/10.3390/ma11091625	ADP
admet-1317	478	7	https://doi.org/10.1016/j.jconrel.2012.05.030	https://doi.org/10.1016/j.jconrel.2012.05.030	PROPN
admet-1317	478	8	https://doi.org/10.1016/j.ejpb.2019.12.008	https://doi.org/10.1016/j.ejpb.2019.12.008	PROPN
admet-1317	478	9	https://doi.org/10.1016/j.ejpb.2018.05.017	https://doi.org/10.1016/j.ejpb.2018.05.017	PROPN
admet-1317	478	10	https://doi.org/10.1016/j.ijpharm.2015.01.019	https://doi.org/10.1016/j.ijpharm.2015.01.019	PROPN
admet-1317	478	11	https://doi.org/10.1039/c7ra10928h	https://doi.org/10.1039/c7ra10928h	PROPN
admet-1317	478	12	https://doi.org/10.1039/c7ra10928h	https://doi.org/10.1039/c7ra10928h	PROPN
admet-1317	478	13	https://doi.org/10.1021/acsami.9b15668	https://doi.org/10.1021/acsami.9b15668	NOUN
admet-1317	478	14	https://doi.org/10.1016/j.ijpharm.2017.10.035	https://doi.org/10.1016/j.ijpharm.2017.10.035	NOUN
admet-1317	478	15	https://doi.org/10.1016/j.ejpb.2013.10.001	https://doi.org/10.1016/j.ejpb.2013.10.001	NOUN
admet-1317	478	16	https://doi.org/10.1088/0960-1317/26/1/013002	https://doi.org/10.1088/0960-1317/26/1/013002	PROPN
admet-1317	478	17	https://doi.org/10.1517/17425241003628171	https://doi.org/10.1517/17425241003628171	NOUN
admet-1317	479	1	https://doi.org/10.1016/j.jconrel.2010.07.104	https://doi.org/10.1016/j.jconrel.2010.07.104	PROPN
admet-1317	479	2	https://doi.org/10.1016/j.jconrel.2016.08.031	https://doi.org/10.1016/j.jconrel.2016.08.031	PROPN
admet-1317	479	3	r.f	r.f	PROPN
admet-1317	479	4	.	.	PROPN
admet-1317	479	5	ghazi	ghazi	PROPN
admet-1317	479	6	and	and	CCONJ
admet-1317	479	7	m.h	m.h	PROPN
admet-1317	479	8	.	.	PROPN
admet-1317	479	9	al	al	PROPN
admet-1317	479	10	-	-	PUNCT
admet-1317	479	11	mayahy	mayahy	PROPN
admet-1317	479	12	admet	admet	PROPN
admet-1317	479	13	&	&	CCONJ
admet-1317	479	14	dmpk	dmpk	PROPN
admet-1317	479	15	10(3	10(3	NUM
admet-1317	479	16	)	)	PUNCT
admet-1317	479	17	(	(	PUNCT
admet-1317	479	18	2022	2022	NUM
admet-1317	479	19	)	)	PUNCT
admet-1317	479	20	213	213	NUM
admet-1317	479	21	-	-	SYM
admet-1317	479	22	230	230	NUM
admet-1317	479	23	230	230	NUM
admet-1317	479	24	[	[	SYM
admet-1317	479	25	32	32	NUM
admet-1317	479	26	]	]	PUNCT
admet-1317	479	27	y.	y.	PROPN
admet-1317	479	28	kim	kim	PROPN
admet-1317	479	29	,	,	PUNCT
admet-1317	479	30	s.a	s.a	PROPN
admet-1317	479	31	.	.	PROPN
admet-1317	479	32	bhattaccharjee	bhattaccharjee	PROPN
admet-1317	479	33	,	,	PUNCT
admet-1317	479	34	m.	m.	NOUN
admet-1317	479	35	beck	beck	PROPN
admet-1317	479	36	-	-	PUNCT
admet-1317	479	37	broichsitter	broichsitter	NOUN
admet-1317	479	38	,	,	PUNCT
admet-1317	479	39	a.k	a.k	PROPN
admet-1317	479	40	.	.	PROPN
admet-1317	479	41	banga	banga	PROPN
admet-1317	479	42	.	.	PUNCT
admet-1317	480	1	fabrication	fabrication	NOUN
admet-1317	480	2	and	and	CCONJ
admet-1317	480	3	characterization	characterization	NOUN
admet-1317	480	4	of	of	ADP
admet-1317	480	5	hyaluronic	hyaluronic	ADJ
admet-1317	480	6	acid	acid	NOUN
admet-1317	480	7	microneedles	microneedle	NOUN
admet-1317	480	8	to	to	PART
admet-1317	480	9	enhance	enhance	VERB
admet-1317	480	10	delivery	delivery	NOUN
admet-1317	480	11	of	of	ADP
admet-1317	480	12	magnesium	magnesium	NOUN
admet-1317	480	13	ascorbyl	ascorbyl	NOUN
admet-1317	480	14	phosphate	phosphate	NOUN
admet-1317	480	15	into	into	ADP
admet-1317	480	16	skin	skin	NOUN
admet-1317	480	17	.	.	PUNCT
admet-1317	481	1	biomedical	biomedical	ADJ
admet-1317	481	2	microdevices	microdevice	NOUN
admet-1317	481	3	21	21	NUM
admet-1317	481	4	(	(	PUNCT
admet-1317	481	5	2019	2019	NUM
admet-1317	481	6	)	)	PUNCT
admet-1317	481	7	1	1	NUM
admet-1317	481	8	-	-	SYM
admet-1317	481	9	9	9	NUM
admet-1317	481	10	.	.	PUNCT
admet-1317	481	11	https://doi.org/10.1007/s10544-019-0455-0	https://doi.org/10.1007/s10544-019-0455-0	NUM
admet-1317	481	12	.	.	PUNCT
admet-1317	482	1	[	[	X
admet-1317	482	2	33	33	NUM
admet-1317	482	3	]	]	X
admet-1317	482	4	s.p	s.p	PROPN
admet-1317	482	5	.	.	PROPN
admet-1317	482	6	davis	davis	PROPN
admet-1317	482	7	,	,	PUNCT
admet-1317	482	8	b.j	b.j	PROPN
admet-1317	482	9	.	.	PROPN
admet-1317	482	10	landis	landis	PROPN
admet-1317	482	11	,	,	PUNCT
admet-1317	482	12	z.h	z.h	PROPN
admet-1317	482	13	.	.	PROPN
admet-1317	482	14	adams	adams	PROPN
admet-1317	482	15	,	,	PUNCT
admet-1317	482	16	m.g	m.g	PROPN
admet-1317	482	17	.	.	PROPN
admet-1317	482	18	allen	allen	PROPN
admet-1317	482	19	,	,	PUNCT
admet-1317	482	20	m.r	m.r	PROPN
admet-1317	482	21	.	.	PROPN
admet-1317	482	22	prausnitz	prausnitz	NOUN
admet-1317	482	23	.	.	PUNCT
admet-1317	483	1	insertion	insertion	NOUN
admet-1317	483	2	of	of	ADP
admet-1317	483	3	microneedles	microneedle	NOUN
admet-1317	483	4	into	into	ADP
admet-1317	483	5	skin	skin	NOUN
admet-1317	483	6	:	:	PUNCT
admet-1317	483	7	measurement	measurement	NOUN
admet-1317	483	8	and	and	CCONJ
admet-1317	483	9	prediction	prediction	NOUN
admet-1317	483	10	of	of	ADP
admet-1317	483	11	insertion	insertion	NOUN
admet-1317	483	12	force	force	NOUN
admet-1317	483	13	and	and	CCONJ
admet-1317	483	14	needle	needle	NOUN
admet-1317	483	15	fracture	fracture	PROPN
admet-1317	483	16	force	force	NOUN
admet-1317	483	17	.	.	PUNCT
admet-1317	484	1	journal	journal	NOUN
admet-1317	484	2	of	of	ADP
admet-1317	484	3	biomechanics	biomechanic	NOUN
admet-1317	484	4	37	37	NUM
admet-1317	484	5	(	(	PUNCT
admet-1317	484	6	2004	2004	NUM
admet-1317	484	7	)	)	PUNCT
admet-1317	484	8	1155	1155	NUM
admet-1317	484	9	-	-	SYM
admet-1317	484	10	1163	1163	NUM
admet-1317	484	11	.	.	PUNCT
admet-1317	485	1	https://doi.org/10.1016/j.jbiomech.2003.12.010	https://doi.org/10.1016/j.jbiomech.2003.12.010	NOUN
admet-1317	485	2	.	.	PUNCT
admet-1317	486	1	[	[	X
admet-1317	486	2	34	34	NUM
admet-1317	486	3	]	]	SYM
admet-1317	486	4	m.g.a	m.g.a	NOUN
admet-1317	486	5	.	.	PUNCT
admet-1317	486	6	vieira	vieira	PROPN
admet-1317	486	7	,	,	PUNCT
admet-1317	486	8	m.a	m.a	PROPN
admet-1317	486	9	.	.	PROPN
admet-1317	486	10	da	da	PROPN
admet-1317	486	11	silva	silva	PROPN
admet-1317	486	12	,	,	PUNCT
admet-1317	486	13	l.o	l.o	PROPN
admet-1317	486	14	.	.	PROPN
admet-1317	486	15	dos	dos	PROPN
admet-1317	486	16	santos	santos	PROPN
admet-1317	486	17	,	,	PUNCT
admet-1317	486	18	m.m	m.m	PROPN
admet-1317	486	19	.	.	PROPN
admet-1317	486	20	beppu	beppu	PROPN
admet-1317	486	21	.	.	PUNCT
admet-1317	487	1	natural	natural	ADJ
admet-1317	487	2	-	-	PUNCT
admet-1317	487	3	based	base	VERB
admet-1317	487	4	plasticizers	plasticizer	NOUN
admet-1317	487	5	and	and	CCONJ
admet-1317	487	6	biopolymer	biopolymer	NOUN
admet-1317	487	7	films	film	NOUN
admet-1317	487	8	:	:	PUNCT
admet-1317	487	9	a	a	DET
admet-1317	487	10	review	review	NOUN
admet-1317	487	11	.	.	PUNCT
admet-1317	488	1	european	european	ADJ
admet-1317	488	2	polymer	polymer	PROPN
admet-1317	488	3	journal	journal	NOUN
admet-1317	488	4	47	47	NUM
admet-1317	488	5	(	(	PUNCT
admet-1317	488	6	2011	2011	NUM
admet-1317	488	7	)	)	PUNCT
admet-1317	488	8	254	254	NUM
admet-1317	488	9	-	-	SYM
admet-1317	488	10	263	263	NUM
admet-1317	488	11	.	.	PUNCT
admet-1317	489	1	https://doi.org/10.1016/j.eurpolymj.2010.12.011	https://doi.org/10.1016/j.eurpolymj.2010.12.011	NUM
admet-1317	489	2	.	.	PUNCT
admet-1317	490	1	[	[	X
admet-1317	490	2	35	35	NUM
admet-1317	490	3	]	]	X
admet-1317	490	4	q.l	q.l	PROPN
admet-1317	490	5	.	.	PROPN
admet-1317	490	6	wang	wang	PROPN
admet-1317	490	7	,	,	PUNCT
admet-1317	490	8	d.d	d.d	PROPN
admet-1317	490	9	.	.	PROPN
admet-1317	490	10	zhu	zhu	PROPN
admet-1317	490	11	,	,	PUNCT
admet-1317	490	12	x.b	x.b	PROPN
admet-1317	490	13	.	.	PROPN
admet-1317	490	14	liu	liu	PROPN
admet-1317	490	15	,	,	PUNCT
admet-1317	490	16	b.z	b.z	PROPN
admet-1317	490	17	.	.	PROPN
admet-1317	490	18	chen	chen	PROPN
admet-1317	490	19	,	,	PUNCT
admet-1317	490	20	x.d	x.d	PROPN
admet-1317	490	21	.	.	PROPN
admet-1317	490	22	guo	guo	PROPN
admet-1317	490	23	.	.	PUNCT
admet-1317	491	1	microneedles	microneedle	NOUN
admet-1317	491	2	with	with	ADP
admet-1317	491	3	controlled	control	VERB
admet-1317	491	4	bubble	bubble	NOUN
admet-1317	491	5	sizes	size	NOUN
admet-1317	491	6	and	and	CCONJ
admet-1317	491	7	drug	drug	NOUN
admet-1317	491	8	distributions	distribution	NOUN
admet-1317	491	9	for	for	ADP
admet-1317	491	10	efficient	efficient	ADJ
admet-1317	491	11	transdermal	transdermal	ADJ
admet-1317	491	12	drug	drug	NOUN
admet-1317	491	13	delivery	delivery	NOUN
admet-1317	491	14	.	.	PUNCT
admet-1317	492	1	sci	sci	PROPN
admet-1317	492	2	.	.	PROPN
admet-1317	492	3	rep	rep	PROPN
admet-1317	492	4	.	.	PROPN
admet-1317	492	5	6	6	NUM
admet-1317	492	6	(	(	PUNCT
admet-1317	492	7	2016	2016	NUM
admet-1317	492	8	)	)	PUNCT
admet-1317	492	9	38755	38755	NUM
admet-1317	492	10	.	.	PUNCT
admet-1317	493	1	https://doi.org/10.1038/srep38755	https://doi.org/10.1038/srep38755	PROPN
admet-1317	493	2	.	.	PUNCT
admet-1317	494	1	[	[	X
admet-1317	494	2	36	36	NUM
admet-1317	494	3	]	]	X
admet-1317	494	4	d.f.s	d.f.s	ADJ
admet-1317	494	5	.	.	PUNCT
admet-1317	494	6	fonseca	fonseca	PROPN
admet-1317	494	7	,	,	PUNCT
admet-1317	494	8	c.	c.	PROPN
admet-1317	494	9	vilela	vilela	PROPN
admet-1317	494	10	,	,	PUNCT
admet-1317	494	11	a.j.d	a.j.d	NOUN
admet-1317	494	12	.	.	PUNCT
admet-1317	495	1	silvestre	silvestre	PROPN
admet-1317	495	2	,	,	PUNCT
admet-1317	495	3	c.s.r	c.s.r	PROPN
admet-1317	495	4	.	.	PROPN
admet-1317	495	5	freire	freire	PROPN
admet-1317	495	6	.	.	PUNCT
admet-1317	496	1	a	a	DET
admet-1317	496	2	compendium	compendium	NOUN
admet-1317	496	3	of	of	ADP
admet-1317	496	4	current	current	ADJ
admet-1317	496	5	developments	development	NOUN
admet-1317	496	6	on	on	ADP
admet-1317	496	7	polysaccharide	polysaccharide	NOUN
admet-1317	496	8	and	and	CCONJ
admet-1317	496	9	protein	protein	NOUN
admet-1317	496	10	-	-	PUNCT
admet-1317	496	11	based	base	VERB
admet-1317	496	12	microneedles	microneedle	NOUN
admet-1317	496	13	.	.	PUNCT
admet-1317	497	1	int	int	NOUN
admet-1317	497	2	.	.	PUNCT
admet-1317	498	1	j.	j.	PROPN
admet-1317	498	2	biol	biol	PROPN
admet-1317	498	3	.	.	PUNCT
admet-1317	499	1	macromol	macromol	PROPN
admet-1317	499	2	.	.	PROPN
admet-1317	500	1	136	136	NUM
admet-1317	500	2	(	(	PUNCT
admet-1317	500	3	2019	2019	NUM
admet-1317	500	4	)	)	PUNCT
admet-1317	500	5	704	704	NUM
admet-1317	500	6	-	-	SYM
admet-1317	500	7	728	728	NUM
admet-1317	500	8	.	.	PUNCT
admet-1317	501	1	https://doi.org/10.1016/j.ijbiomac.2019.04.163	https://doi.org/10.1016/j.ijbiomac.2019.04.163	NOUN
admet-1317	501	2	.	.	PUNCT
admet-1317	502	1	[	[	X
admet-1317	502	2	37	37	NUM
admet-1317	502	3	]	]	PUNCT
admet-1317	502	4	k.	k.	PROPN
admet-1317	502	5	saraswathy	saraswathy	PROPN
admet-1317	502	6	,	,	PUNCT
admet-1317	502	7	g.	g.	PROPN
admet-1317	502	8	agarwal	agarwal	PROPN
admet-1317	502	9	,	,	PUNCT
admet-1317	502	10	a.	a.	PROPN
admet-1317	502	11	srivastava	srivastava	PROPN
admet-1317	502	12	.	.	PUNCT
admet-1317	502	13	hyaluronic	hyaluronic	ADJ
admet-1317	502	14	acid	acid	NOUN
admet-1317	502	15	microneedles‐laden	microneedles‐laden	PROPN
admet-1317	502	16	collagen	collagen	NOUN
admet-1317	502	17	cryogel	cryogel	NOUN
admet-1317	502	18	plugs	plug	NOUN
admet-1317	502	19	for	for	ADP
admet-1317	502	20	ocular	ocular	ADJ
admet-1317	502	21	drug	drug	NOUN
admet-1317	502	22	delivery	delivery	NOUN
admet-1317	502	23	.	.	PUNCT
admet-1317	503	1	journal	journal	NOUN
admet-1317	503	2	of	of	ADP
admet-1317	503	3	applied	apply	VERB
admet-1317	503	4	polymer	polymer	NOUN
admet-1317	503	5	science	science	NOUN
admet-1317	503	6	137	137	NUM
admet-1317	503	7	(	(	PUNCT
admet-1317	503	8	2020	2020	NUM
admet-1317	503	9	)	)	PUNCT
admet-1317	503	10	49285	49285	NUM
admet-1317	503	11	.	.	PUNCT
admet-1317	504	1	https://doi.org/10.1002/app.49285	https://doi.org/10.1002/app.49285	PROPN
admet-1317	504	2	.	.	PUNCT
admet-1317	505	1	[	[	X
admet-1317	505	2	38	38	NUM
admet-1317	505	3	]	]	SYM
admet-1317	505	4	m.i	m.i	PROPN
admet-1317	505	5	.	.	PROPN
admet-1317	505	6	haq	haq	PROPN
admet-1317	505	7	,	,	PUNCT
admet-1317	505	8	e.	e.	PROPN
admet-1317	505	9	smith	smith	PROPN
admet-1317	505	10	,	,	PUNCT
admet-1317	505	11	d.n	d.n	PROPN
admet-1317	505	12	.	.	PROPN
admet-1317	505	13	john	john	PROPN
admet-1317	505	14	,	,	PUNCT
admet-1317	505	15	m.	m.	PROPN
admet-1317	505	16	kalavala	kalavala	PROPN
admet-1317	505	17	,	,	PUNCT
admet-1317	505	18	c.	c.	PROPN
admet-1317	505	19	edwards	edwards	PROPN
admet-1317	505	20	,	,	PUNCT
admet-1317	505	21	a.	a.	NOUN
admet-1317	505	22	anstey	anstey	PROPN
admet-1317	505	23	,	,	PUNCT
admet-1317	505	24	a.	a.	PROPN
admet-1317	505	25	morrissey	morrissey	PROPN
admet-1317	505	26	,	,	PUNCT
admet-1317	505	27	j.c	j.c	PROPN
admet-1317	505	28	.	.	PROPN
admet-1317	505	29	birchall	birchall	PROPN
admet-1317	505	30	.	.	PUNCT
admet-1317	506	1	clinical	clinical	ADJ
admet-1317	506	2	administration	administration	NOUN
admet-1317	506	3	of	of	ADP
admet-1317	506	4	microneedles	microneedle	NOUN
admet-1317	506	5	:	:	PUNCT
admet-1317	506	6	skin	skin	NOUN
admet-1317	506	7	puncture	puncture	NOUN
admet-1317	506	8	,	,	PUNCT
admet-1317	506	9	pain	pain	NOUN
admet-1317	506	10	and	and	CCONJ
admet-1317	506	11	sensation	sensation	NOUN
admet-1317	506	12	.	.	PUNCT
admet-1317	507	1	biomed	biome	VERB
admet-1317	507	2	.	.	PUNCT
admet-1317	508	1	microdevices	microdevice	VERB
admet-1317	508	2	11	11	NUM
admet-1317	508	3	(	(	PUNCT
admet-1317	508	4	2009	2009	NUM
admet-1317	508	5	)	)	PUNCT
admet-1317	508	6	35	35	NUM
admet-1317	508	7	-	-	SYM
admet-1317	508	8	47	47	NUM
admet-1317	508	9	.	.	PUNCT
admet-1317	509	1	https://doi.org/10.1007/s10544-008-9208-1	https://doi.org/10.1007/s10544-008-9208-1	NOUN
admet-1317	509	2	.	.	PUNCT
admet-1317	510	1	[	[	X
admet-1317	510	2	39	39	NUM
admet-1317	510	3	]	]	PUNCT
admet-1317	510	4	m.	m.	NOUN
admet-1317	510	5	yang	yang	PROPN
admet-1317	510	6	,	,	PUNCT
admet-1317	510	7	j.d	j.d	PROPN
admet-1317	510	8	.	.	PROPN
admet-1317	510	9	zahn	zahn	PROPN
admet-1317	510	10	.	.	PROPN
admet-1317	510	11	microneedle	microneedle	PROPN
admet-1317	510	12	insertion	insertion	NOUN
admet-1317	510	13	force	force	NOUN
admet-1317	510	14	reduction	reduction	NOUN
admet-1317	510	15	using	use	VERB
admet-1317	510	16	vibratory	vibratory	ADJ
admet-1317	510	17	actuation	actuation	NOUN
admet-1317	510	18	.	.	PUNCT
admet-1317	511	1	biomedical	biomedical	ADJ
admet-1317	511	2	microdevices	microdevice	NOUN
admet-1317	511	3	6	6	NUM
admet-1317	511	4	(	(	PUNCT
admet-1317	511	5	2004	2004	NUM
admet-1317	511	6	)	)	PUNCT
admet-1317	511	7	177	177	NUM
admet-1317	511	8	-	-	SYM
admet-1317	511	9	182	182	NUM
admet-1317	511	10	.	.	PUNCT
admet-1317	511	11	https://doi.org/10.1023/b:bmmd.0000042046.07678.2e	https://doi.org/10.1023/b:bmmd.0000042046.07678.2e	NOUN
admet-1317	511	12	.	.	PUNCT
admet-1317	512	1	[	[	X
admet-1317	512	2	40	40	NUM
admet-1317	512	3	]	]	X
admet-1317	512	4	j.w	j.w	PROPN
admet-1317	512	5	.	.	PROPN
admet-1317	512	6	lee	lee	PROPN
admet-1317	512	7	,	,	PUNCT
admet-1317	512	8	j.h	j.h	PROPN
admet-1317	512	9	.	.	PROPN
admet-1317	512	10	park	park	PROPN
admet-1317	512	11	,	,	PUNCT
admet-1317	512	12	m.r	m.r	PROPN
admet-1317	512	13	.	.	PROPN
admet-1317	512	14	prausnitz	prausnitz	NOUN
admet-1317	512	15	.	.	PUNCT
admet-1317	513	1	dissolving	dissolve	VERB
admet-1317	513	2	microneedles	microneedle	NOUN
admet-1317	513	3	for	for	ADP
admet-1317	513	4	transdermal	transdermal	ADJ
admet-1317	513	5	drug	drug	NOUN
admet-1317	513	6	delivery	delivery	NOUN
admet-1317	513	7	.	.	PUNCT
admet-1317	514	1	biomaterials	biomaterial	NOUN
admet-1317	514	2	29	29	NUM
admet-1317	514	3	(	(	PUNCT
admet-1317	514	4	2008	2008	NUM
admet-1317	514	5	)	)	PUNCT
admet-1317	514	6	2113	2113	NUM
admet-1317	514	7	-	-	SYM
admet-1317	514	8	2124	2124	NUM
admet-1317	514	9	.	.	PUNCT
admet-1317	515	1	https://doi.org/10.1016/j.biomaterials.2007.12.048	https://doi.org/10.1016/j.biomaterials.2007.12.048	ADJ
admet-1317	515	2	.	.	PUNCT
admet-1317	516	1	[	[	X
admet-1317	516	2	41	41	NUM
admet-1317	516	3	]	]	X
admet-1317	516	4	h.x	h.x	PROPN
admet-1317	516	5	.	.	PROPN
admet-1317	516	6	nguyen	nguyen	PROPN
admet-1317	516	7	,	,	PUNCT
admet-1317	516	8	a.k	a.k	PROPN
admet-1317	516	9	.	.	PROPN
admet-1317	516	10	banga	banga	PROPN
admet-1317	516	11	.	.	PUNCT
admet-1317	517	1	enhanced	enhance	VERB
admet-1317	517	2	skin	skin	NOUN
admet-1317	517	3	delivery	delivery	NOUN
admet-1317	517	4	of	of	ADP
admet-1317	517	5	vismodegib	vismodegib	NOUN
admet-1317	517	6	by	by	ADP
admet-1317	517	7	microneedle	microneedle	NOUN
admet-1317	517	8	treatment	treatment	NOUN
admet-1317	517	9	.	.	PUNCT
admet-1317	518	1	drug	drug	PROPN
admet-1317	518	2	deliv	deliv	PROPN
admet-1317	518	3	transl	transl	PROPN
admet-1317	518	4	.	.	PUNCT
admet-1317	519	1	res	re	NOUN
admet-1317	519	2	.	.	PROPN
admet-1317	519	3	5	5	NUM
admet-1317	519	4	(	(	PUNCT
admet-1317	519	5	2015	2015	NUM
admet-1317	519	6	)	)	PUNCT
admet-1317	519	7	407	407	NUM
admet-1317	519	8	-	-	SYM
admet-1317	519	9	423	423	NUM
admet-1317	519	10	.	.	PUNCT
admet-1317	520	1	https://doi.org/10.1007/s13346-015-0241-3	https://doi.org/10.1007/s13346-015-0241-3	NOUN
admet-1317	520	2	.	.	PUNCT
admet-1317	521	1	[	[	X
admet-1317	521	2	42	42	NUM
admet-1317	521	3	]	]	X
admet-1317	521	4	h.x	h.x	PROPN
admet-1317	521	5	.	.	PROPN
admet-1317	521	6	nguyen	nguyen	PROPN
admet-1317	521	7	,	,	PUNCT
admet-1317	521	8	a.k	a.k	PROPN
admet-1317	521	9	.	.	PROPN
admet-1317	521	10	banga	banga	PROPN
admet-1317	521	11	.	.	PUNCT
admet-1317	522	1	delivery	delivery	NOUN
admet-1317	522	2	of	of	ADP
admet-1317	522	3	methotrexate	methotrexate	NOUN
admet-1317	522	4	and	and	CCONJ
admet-1317	522	5	characterization	characterization	NOUN
admet-1317	522	6	of	of	ADP
admet-1317	522	7	skin	skin	NOUN
admet-1317	522	8	treated	treat	VERB
admet-1317	522	9	by	by	ADP
admet-1317	522	10	fabricated	fabricate	VERB
admet-1317	522	11	plga	plga	NOUN
admet-1317	522	12	microneedles	microneedle	NOUN
admet-1317	522	13	and	and	CCONJ
admet-1317	522	14	fractional	fractional	ADJ
admet-1317	522	15	ablative	ablative	ADJ
admet-1317	522	16	laser	laser	NOUN
admet-1317	522	17	.	.	PUNCT
admet-1317	523	1	pharm	pharm	NOUN
admet-1317	523	2	.	.	PUNCT
admet-1317	524	1	res	re	NOUN
admet-1317	524	2	.	.	PROPN
admet-1317	525	1	35	35	NUM
admet-1317	525	2	(	(	PUNCT
admet-1317	525	3	2018	2018	NUM
admet-1317	525	4	)	)	PUNCT
admet-1317	525	5	68	68	NUM
admet-1317	525	6	.	.	PUNCT
admet-1317	525	7	https://doi.org/10.1007/s11095-018-2369-6	https://doi.org/10.1007/s11095-018-2369-6	NUM
admet-1317	525	8	.	.	PUNCT
admet-1317	526	1	[	[	X
admet-1317	526	2	43	43	NUM
admet-1317	526	3	]	]	X
admet-1317	526	4	b.m	b.m	PROPN
admet-1317	526	5	.	.	PROPN
admet-1317	526	6	lee	lee	PROPN
admet-1317	526	7	,	,	PUNCT
admet-1317	526	8	c.	c.	PROPN
admet-1317	526	9	lee	lee	PROPN
admet-1317	526	10	,	,	PUNCT
admet-1317	526	11	s.f	s.f	PROPN
admet-1317	526	12	.	.	PROPN
admet-1317	526	13	lahiji	lahiji	PROPN
admet-1317	526	14	,	,	PUNCT
admet-1317	526	15	u.w	u.w	PROPN
admet-1317	526	16	.	.	PROPN
admet-1317	526	17	jung	jung	PROPN
admet-1317	526	18	,	,	PUNCT
admet-1317	526	19	g.	g.	PROPN
admet-1317	526	20	chung	chung	PROPN
admet-1317	526	21	,	,	PUNCT
admet-1317	526	22	h.	h.	PROPN
admet-1317	526	23	jung	jung	PROPN
admet-1317	526	24	.	.	PUNCT
admet-1317	527	1	dissolving	dissolve	VERB
admet-1317	527	2	microneedles	microneedle	NOUN
admet-1317	527	3	for	for	ADP
admet-1317	527	4	rapid	rapid	ADJ
admet-1317	527	5	and	and	CCONJ
admet-1317	527	6	painless	painless	ADJ
admet-1317	527	7	local	local	ADJ
admet-1317	527	8	anesthesia	anesthesia	NOUN
admet-1317	527	9	.	.	PUNCT
admet-1317	528	1	pharmaceutics	pharmaceutic	NOUN
admet-1317	528	2	12	12	NUM
admet-1317	528	3	(	(	PUNCT
admet-1317	528	4	2020	2020	NUM
admet-1317	528	5	)	)	PUNCT
admet-1317	528	6	366	366	NUM
admet-1317	528	7	.	.	PUNCT
admet-1317	529	1	https://doi.org/10.3390/pharmaceutics12040366	https://doi.org/10.3390/pharmaceutics12040366	PROPN
admet-1317	529	2	.	.	PUNCT
admet-1317	530	1	[	[	X
admet-1317	530	2	44	44	NUM
admet-1317	530	3	]	]	PUNCT
admet-1317	530	4	z.	z.	PROPN
admet-1317	530	5	zhu	zhu	PROPN
admet-1317	530	6	,	,	PUNCT
admet-1317	530	7	h.	h.	PROPN
admet-1317	530	8	luo	luo	PROPN
admet-1317	530	9	,	,	PUNCT
admet-1317	530	10	w.	w.	PROPN
admet-1317	530	11	lu	lu	PROPN
admet-1317	530	12	,	,	PUNCT
admet-1317	530	13	h.	h.	PROPN
admet-1317	530	14	luan	luan	PROPN
admet-1317	530	15	,	,	PUNCT
admet-1317	530	16	y.	y.	PROPN
admet-1317	530	17	wu	wu	PROPN
admet-1317	530	18	,	,	PUNCT
admet-1317	530	19	j.	j.	PROPN
admet-1317	530	20	luo	luo	PROPN
admet-1317	530	21	,	,	PUNCT
admet-1317	530	22	y.	y.	PROPN
admet-1317	530	23	wang	wang	PROPN
admet-1317	530	24	,	,	PUNCT
admet-1317	530	25	j.	j.	PROPN
admet-1317	530	26	pi	pi	PROPN
admet-1317	530	27	,	,	PUNCT
admet-1317	530	28	c.y	c.y	PROPN
admet-1317	530	29	.	.	PROPN
admet-1317	530	30	lim	lim	PROPN
admet-1317	530	31	,	,	PUNCT
admet-1317	530	32	h.	h.	PROPN
admet-1317	530	33	wang	wang	PROPN
admet-1317	530	34	.	.	PUNCT
admet-1317	531	1	rapidly	rapidly	ADV
admet-1317	531	2	dissolvable	dissolvable	ADJ
admet-1317	531	3	microneedle	microneedle	NOUN
admet-1317	531	4	patches	patch	NOUN
admet-1317	531	5	for	for	ADP
admet-1317	531	6	transdermal	transdermal	ADJ
admet-1317	531	7	delivery	delivery	NOUN
admet-1317	531	8	of	of	ADP
admet-1317	531	9	exenatide	exenatide	NOUN
admet-1317	531	10	.	.	PUNCT
admet-1317	532	1	pharm	pharm	NOUN
admet-1317	532	2	.	.	PUNCT
admet-1317	533	1	res	re	NOUN
admet-1317	533	2	.	.	PROPN
admet-1317	534	1	31	31	NUM
admet-1317	534	2	(	(	PUNCT
admet-1317	534	3	2014	2014	NUM
admet-1317	534	4	)	)	PUNCT
admet-1317	534	5	3348	3348	NUM
admet-1317	534	6	-	-	SYM
admet-1317	534	7	3360	3360	NUM
admet-1317	534	8	.	.	PUNCT
admet-1317	535	1	https://doi.org/10.1007/s11095-014-1424-1	https://doi.org/10.1007/s11095-014-1424-1	NUM
admet-1317	535	2	.	.	PUNCT
admet-1317	536	1	[	[	X
admet-1317	536	2	45	45	NUM
admet-1317	536	3	]	]	X
admet-1317	536	4	y.	y.	PROPN
admet-1317	536	5	park	park	PROPN
admet-1317	536	6	,	,	PUNCT
admet-1317	536	7	j.	j.	PROPN
admet-1317	536	8	park	park	PROPN
admet-1317	536	9	,	,	PUNCT
admet-1317	536	10	g.s	g.s	PROPN
admet-1317	536	11	.	.	PROPN
admet-1317	536	12	chu	chu	PROPN
admet-1317	536	13	,	,	PUNCT
admet-1317	536	14	k.s	k.s	PROPN
admet-1317	536	15	.	.	PROPN
admet-1317	536	16	kim	kim	PROPN
admet-1317	536	17	,	,	PUNCT
admet-1317	536	18	j.h	j.h	PROPN
admet-1317	536	19	.	.	PROPN
admet-1317	536	20	sung	sung	PROPN
admet-1317	536	21	,	,	PUNCT
admet-1317	536	22	b.	b.	PROPN
admet-1317	536	23	kim	kim	PROPN
admet-1317	536	24	.	.	PUNCT
admet-1317	537	1	transdermal	transdermal	ADJ
admet-1317	537	2	delivery	delivery	NOUN
admet-1317	537	3	of	of	ADP
admet-1317	537	4	cosmetic	cosmetic	ADJ
admet-1317	537	5	ingredients	ingredient	NOUN
admet-1317	537	6	using	use	VERB
admet-1317	537	7	dissolving	dissolve	VERB
admet-1317	537	8	polymer	polymer	NOUN
admet-1317	537	9	microneedle	microneedle	NOUN
admet-1317	537	10	arrays	array	VERB
admet-1317	537	11	.	.	PUNCT
admet-1317	538	1	biotechnology	biotechnology	NOUN
admet-1317	538	2	and	and	CCONJ
admet-1317	538	3	bioprocess	bioprocess	NOUN
admet-1317	538	4	engineering	engineering	NOUN
admet-1317	538	5	20	20	NUM
admet-1317	538	6	(	(	PUNCT
admet-1317	538	7	2015	2015	NUM
admet-1317	538	8	)	)	PUNCT
admet-1317	538	9	543	543	NUM
admet-1317	538	10	-	-	SYM
admet-1317	538	11	549	549	NUM
admet-1317	538	12	.	.	PUNCT
admet-1317	538	13	https://doi.org/10.1007/s12257-014-0775-0	https://doi.org/10.1007/s12257-014-0775-0	NUM
admet-1317	538	14	.	.	PUNCT
admet-1317	539	1	[	[	X
admet-1317	539	2	46	46	NUM
admet-1317	539	3	]	]	X
admet-1317	539	4	v.	v.	PROPN
admet-1317	539	5	kumar	kumar	PROPN
admet-1317	539	6	,	,	PUNCT
admet-1317	539	7	s.	s.	PROPN
admet-1317	539	8	mahant	mahant	PROPN
admet-1317	539	9	,	,	PUNCT
admet-1317	539	10	r.	r.	PROPN
admet-1317	539	11	rao	rao	PROPN
admet-1317	539	12	,	,	PUNCT
admet-1317	539	13	s.	s.	PROPN
admet-1317	539	14	nanda	nanda	PROPN
admet-1317	539	15	.	.	PUNCT
admet-1317	539	16	emulgel	emulgel	PROPN
admet-1317	539	17	based	base	VERB
admet-1317	539	18	topical	topical	ADJ
admet-1317	539	19	delivery	delivery	NOUN
admet-1317	539	20	system	system	NOUN
admet-1317	539	21	for	for	ADP
admet-1317	539	22	loratadine	loratadine	NOUN
admet-1317	539	23	.	.	PUNCT
admet-1317	540	1	admet	admet	PROPN
admet-1317	540	2	and	and	CCONJ
admet-1317	540	3	dmpk	dmpk	X
admet-1317	540	4	2	2	NUM
admet-1317	540	5	(	(	PUNCT
admet-1317	540	6	2014	2014	NUM
admet-1317	540	7	)	)	PUNCT
admet-1317	540	8	254	254	NUM
admet-1317	540	9	-	-	SYM
admet-1317	540	10	271	271	NUM
admet-1317	540	11	.	.	PUNCT
admet-1317	540	12	https://doi.org/10.5599/admet.2.4.64	https://doi.org/10.5599/admet.2.4.64	NOUN
admet-1317	540	13	.	.	PUNCT
admet-1317	541	1	©	©	NOUN
admet-1317	541	2	2022	2022	NUM
admet-1317	541	3	by	by	ADP
admet-1317	541	4	the	the	DET
admet-1317	541	5	authors	author	NOUN
admet-1317	541	6	;	;	PUNCT
admet-1317	541	7	licensee	licensee	PROPN
admet-1317	541	8	iapc	iapc	PROPN
admet-1317	541	9	,	,	PUNCT
admet-1317	541	10	zagreb	zagreb	PROPN
admet-1317	541	11	,	,	PUNCT
admet-1317	541	12	croatia	croatia	PROPN
admet-1317	541	13	.	.	PUNCT
admet-1317	542	1	this	this	DET
admet-1317	542	2	article	article	NOUN
admet-1317	542	3	is	be	AUX
admet-1317	542	4	an	an	DET
admet-1317	542	5	open	open	ADJ
admet-1317	542	6	-	-	PUNCT
admet-1317	542	7	access	access	NOUN
admet-1317	542	8	article	article	NOUN
admet-1317	542	9	distributed	distribute	VERB
admet-1317	542	10	under	under	ADP
admet-1317	542	11	the	the	DET
admet-1317	542	12	terms	term	NOUN
admet-1317	542	13	and	and	CCONJ
admet-1317	542	14	conditions	condition	NOUN
admet-1317	542	15	of	of	ADP
admet-1317	542	16	the	the	DET
admet-1317	542	17	creative	creative	ADJ
admet-1317	542	18	commons	common	NOUN
admet-1317	542	19	attribution	attribution	NOUN
admet-1317	542	20	license	license	NOUN
admet-1317	542	21	(	(	PUNCT
admet-1317	542	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-1317	542	23	)	)	PUNCT
admet-1317	542	24	https://doi.org/10.1007/s10544-019-0455-0	https://doi.org/10.1007/s10544-019-0455-0	NUM
admet-1317	543	1	https://doi.org/10.1016/j.jbiomech.2003.12.010	https://doi.org/10.1016/j.jbiomech.2003.12.010	PROPN
admet-1317	543	2	https://doi.org/10.1016/j.eurpolymj.2010.12.011	https://doi.org/10.1016/j.eurpolymj.2010.12.011	PROPN
admet-1317	543	3	https://doi.org/10.1016/j.eurpolymj.2010.12.011	https://doi.org/10.1016/j.eurpolymj.2010.12.011	PROPN
admet-1317	543	4	https://doi.org/10.1038/srep38755	https://doi.org/10.1038/srep38755	PROPN
admet-1317	543	5	https://doi.org/10.1016/j.ijbiomac.2019.04.163	https://doi.org/10.1016/j.ijbiomac.2019.04.163	PROPN
admet-1317	543	6	https://doi.org/10.1002/app.49285	https://doi.org/10.1002/app.49285	PROPN
admet-1317	543	7	https://doi.org/10.1007/s10544-008-9208-1	https://doi.org/10.1007/s10544-008-9208-1	NUM
admet-1317	543	8	https://doi.org/10.1023/b:bmmd.0000042046.07678.2e	https://doi.org/10.1023/b:bmmd.0000042046.07678.2e	NOUN
admet-1317	543	9	https://doi.org/10.1016/j.biomaterials.2007.12.048	https://doi.org/10.1016/j.biomaterials.2007.12.048	NOUN
admet-1317	543	10	https://doi.org/10.1007/s13346-015-0241-3	https://doi.org/10.1007/s13346-015-0241-3	X
admet-1317	543	11	https://doi.org/10.1007/s11095-018-2369-6	https://doi.org/10.1007/s11095-018-2369-6	NUM
admet-1317	543	12	https://doi.org/10.1007/s11095-018-2369-6	https://doi.org/10.1007/s11095-018-2369-6	NUM
admet-1317	543	13	https://doi.org/10.3390/pharmaceutics12040366	https://doi.org/10.3390/pharmaceutics12040366	ADJ
admet-1317	543	14	https://doi.org/10.3390/pharmaceutics12040366	https://doi.org/10.3390/pharmaceutics12040366	PROPN
admet-1317	543	15	https://doi.org/10.1007/s11095-014-1424-1	https://doi.org/10.1007/s11095-014-1424-1	PROPN
admet-1317	543	16	https://doi.org/10.1007/s12257-014-0775-0	https://doi.org/10.1007/s12257-014-0775-0	NUM
admet-1317	543	17	https://doi.org/10.5599/admet.2.4.64	https://doi.org/10.5599/admet.2.4.64	NOUN
admet-1317	544	1	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN