id	sid	tid	token	lemma	pos
admet-142	1	1	manuscript	manuscript	PROPN
admet-142	1	2	doi	doi	PROPN
admet-142	1	3	:	:	PUNCT
admet-142	1	4	10.5599	10.5599	NUM
admet-142	1	5	/	/	SYM
admet-142	1	6	admet.3.1.142	admet.3.1.142	PROPN
admet-142	1	7	77	77	NUM
admet-142	1	8	admet	admet	X
admet-142	1	9	&	&	CCONJ
admet-142	1	10	dmpk	dmpk	PROPN
admet-142	1	11	3(1	3(1	NUM
admet-142	1	12	)	)	PUNCT
admet-142	1	13	(	(	PUNCT
admet-142	1	14	2015	2015	NUM
admet-142	1	15	)	)	PUNCT
admet-142	1	16	77	77	NUM
admet-142	1	17	-	-	SYM
admet-142	1	18	83	83	NUM
admet-142	1	19	;	;	PUNCT
admet-142	1	20	doi	doi	NOUN
admet-142	1	21	:	:	PUNCT
admet-142	1	22	10.5599	10.5599	NUM
admet-142	1	23	/	/	SYM
admet-142	1	24	admet.3.1.142	admet.3.1.142	PROPN
admet-142	1	25	open	open	ADJ
admet-142	1	26	access	access	NOUN
admet-142	1	27	:	:	PUNCT
admet-142	1	28	issn	issn	PROPN
admet-142	1	29	:	:	PUNCT
admet-142	1	30	1848	1848	NUM
admet-142	1	31	-	-	SYM
admet-142	1	32	7718	7718	NUM
admet-142	1	33	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-142	1	34	note	note	VERB
admet-142	1	35	differential	differential	ADJ
admet-142	1	36	effects	effect	NOUN
admet-142	1	37	of	of	ADP
admet-142	1	38	mitogen	mitogen	NOUN
admet-142	1	39	-	-	PUNCT
admet-142	1	40	activated	activate	VERB
admet-142	1	41	protein	protein	NOUN
admet-142	1	42	kinase	kinase	NOUN
admet-142	1	43	pathway	pathway	NOUN
admet-142	1	44	inhibitors	inhibitor	NOUN
admet-142	1	45	on	on	ADP
admet-142	1	46	p	p	ADJ
admet-142	1	47	-	-	PUNCT
admet-142	1	48	glycoprotein	glycoprotein	NOUN
admet-142	1	49	activation	activation	NOUN
admet-142	1	50	hirokazu	hirokazu	PROPN
admet-142	1	51	wakuda1	wakuda1	PROPN
admet-142	1	52	,	,	PUNCT
admet-142	1	53	*	*	NOUN
admet-142	1	54	,	,	PUNCT
admet-142	1	55	shino	shino	ADJ
admet-142	1	56	miyauchi1	miyauchi1	PROPN
admet-142	1	57	,	,	PUNCT
admet-142	1	58	kana	kana	PROPN
admet-142	1	59	maruyama1	maruyama1	PROPN
admet-142	1	60	,	,	PUNCT
admet-142	1	61	satomi	satomi	PROPN
admet-142	1	62	kagota1	kagota1	PROPN
admet-142	1	63	,	,	PUNCT
admet-142	1	64	kazuki	kazuki	PROPN
admet-142	1	65	nakamura1	nakamura1	PROPN
admet-142	1	66	,	,	PUNCT
admet-142	1	67	keizo	keizo	PROPN
admet-142	1	68	umegaki2	umegaki2	PROPN
admet-142	1	69	,	,	PUNCT
admet-142	1	70	shizuo	shizuo	PROPN
admet-142	1	71	yamada3	yamada3	PROPN
admet-142	1	72	and	and	CCONJ
admet-142	1	73	kazumasa	kazumasa	PROPN
admet-142	1	74	shinozuka1	shinozuka1	PROPN
admet-142	1	75	1	1	NUM
admet-142	1	76	department	department	NOUN
admet-142	1	77	of	of	ADP
admet-142	1	78	pharmacology	pharmacology	NOUN
admet-142	1	79	,	,	PUNCT
admet-142	1	80	school	school	NOUN
admet-142	1	81	of	of	ADP
admet-142	1	82	pharmacy	pharmacy	NOUN
admet-142	1	83	and	and	CCONJ
admet-142	1	84	pharmaceutical	pharmaceutical	NOUN
admet-142	1	85	sciences	science	NOUN
admet-142	1	86	,	,	PUNCT
admet-142	1	87	mukogawa	mukogawa	PROPN
admet-142	1	88	women	women	PROPN
admet-142	1	89	’s	’s	PART
admet-142	1	90	university	university	NOUN
admet-142	1	91	,	,	PUNCT
admet-142	1	92	1168	1168	NUM
admet-142	1	93	koshien	koshien	NOUN
admet-142	1	94	,	,	PUNCT
admet-142	1	95	kyuban	kyuban	NOUN
admet-142	1	96	-	-	PUNCT
admet-142	1	97	cho	cho	NOUN
admet-142	1	98	,	,	PUNCT
admet-142	1	99	nishinomiya	nishinomiya	NOUN
admet-142	1	100	663	663	NUM
admet-142	1	101	-	-	SYM
admet-142	1	102	8179	8179	NUM
admet-142	1	103	,	,	PUNCT
admet-142	1	104	japan	japan	PROPN
admet-142	1	105	2	2	NUM
admet-142	1	106	information	information	NOUN
admet-142	1	107	center	center	NOUN
admet-142	1	108	,	,	PUNCT
admet-142	1	109	national	national	PROPN
admet-142	1	110	institute	institute	PROPN
admet-142	1	111	of	of	ADP
admet-142	1	112	health	health	PROPN
admet-142	1	113	and	and	CCONJ
admet-142	1	114	nutrition	nutrition	NOUN
admet-142	1	115	,	,	PUNCT
admet-142	1	116	1	1	NUM
admet-142	1	117	-	-	SYM
admet-142	1	118	23	23	NUM
admet-142	1	119	-	-	SYM
admet-142	1	120	1	1	NUM
admet-142	1	121	toyama	toyama	NOUN
admet-142	1	122	,	,	PUNCT
admet-142	1	123	shinjuku	shinjuku	PROPN
admet-142	1	124	-	-	PUNCT
admet-142	1	125	ku	ku	PROPN
admet-142	1	126	,	,	PUNCT
admet-142	1	127	tokyo	tokyo	PROPN
admet-142	1	128	162	162	NUM
admet-142	1	129	-	-	SYM
admet-142	1	130	8636	8636	NUM
admet-142	1	131	,	,	PUNCT
admet-142	1	132	japan	japan	PROPN
admet-142	1	133	3	3	NUM
admet-142	1	134	center	center	NOUN
admet-142	1	135	for	for	ADP
admet-142	1	136	pharma	pharma	NOUN
admet-142	1	137	-	-	PUNCT
admet-142	1	138	food	food	NOUN
admet-142	1	139	research	research	NOUN
admet-142	1	140	(	(	PUNCT
admet-142	1	141	cpfr	cpfr	NOUN
admet-142	1	142	)	)	PUNCT
admet-142	1	143	,	,	PUNCT
admet-142	1	144	graduate	graduate	NOUN
admet-142	1	145	school	school	NOUN
admet-142	1	146	of	of	ADP
admet-142	1	147	pharmaceutical	pharmaceutical	NOUN
admet-142	1	148	sciences	science	NOUN
admet-142	1	149	,	,	PUNCT
admet-142	1	150	university	university	PROPN
admet-142	1	151	of	of	ADP
admet-142	1	152	shizuoka	shizuoka	PROPN
admet-142	1	153	,	,	PUNCT
admet-142	1	154	52	52	NUM
admet-142	1	155	-	-	SYM
admet-142	1	156	1	1	NUM
admet-142	1	157	yada	yada	NOUN
admet-142	1	158	,	,	PUNCT
admet-142	1	159	suruga	suruga	PROPN
admet-142	1	160	-	-	PUNCT
admet-142	1	161	ku	ku	PROPN
admet-142	1	162	,	,	PUNCT
admet-142	1	163	shizuoka	shizuoka	PROPN
admet-142	1	164	,	,	PUNCT
admet-142	1	165	shizuoka	shizuoka	PROPN
admet-142	1	166	422	422	NUM
admet-142	1	167	-	-	PUNCT
admet-142	1	168	8526	8526	NUM
admet-142	1	169	,	,	PUNCT
admet-142	1	170	japan	japan	PROPN
admet-142	1	171	*	*	PUNCT
admet-142	1	172	corresponding	correspond	VERB
admet-142	1	173	author	author	NOUN
admet-142	1	174	:	:	PUNCT
admet-142	1	175	e	e	NOUN
admet-142	1	176	-	-	NOUN
admet-142	1	177	mail	mail	NOUN
admet-142	1	178	:	:	PUNCT
admet-142	1	179	wakuda@mukogawa-u.ac.jp	wakuda@mukogawa-u.ac.jp	PUNCT
admet-142	1	180	;	;	PUNCT
admet-142	2	1	tel	tel	PROPN
admet-142	2	2	.	.	PROPN
admet-142	2	3	:	:	PUNCT
admet-142	3	1	+81	+81	ADJ
admet-142	3	2	-	-	PUNCT
admet-142	3	3	798	798	NUM
admet-142	3	4	-	-	PUNCT
admet-142	3	5	45	45	NUM
admet-142	3	6	-	-	PUNCT
admet-142	3	7	9944	9944	NUM
admet-142	3	8	;	;	PUNCT
admet-142	3	9	fax	fax	NOUN
admet-142	3	10	:	:	PUNCT
admet-142	3	11	+81	+81	ADJ
admet-142	3	12	-	-	PUNCT
admet-142	3	13	798	798	NUM
admet-142	3	14	-	-	PUNCT
admet-142	3	15	45	45	NUM
admet-142	3	16	-	-	PUNCT
admet-142	3	17	9944	9944	NUM
admet-142	3	18	received	receive	VERB
admet-142	3	19	:	:	PUNCT
admet-142	3	20	november	november	PROPN
admet-142	3	21	12	12	NUM
admet-142	3	22	,	,	PUNCT
admet-142	3	23	2014	2014	NUM
admet-142	3	24	;	;	PUNCT
admet-142	3	25	revised	revise	VERB
admet-142	3	26	:	:	PUNCT
admet-142	3	27	march	march	PROPN
admet-142	3	28	17	17	NUM
admet-142	3	29	,	,	PUNCT
admet-142	3	30	2015	2015	NUM
admet-142	3	31	;	;	PUNCT
admet-142	3	32	published	publish	VERB
admet-142	3	33	:	:	PUNCT
admet-142	3	34	march	march	PROPN
admet-142	3	35	31	31	NUM
admet-142	3	36	,	,	PUNCT
admet-142	3	37	2015	2015	NUM
admet-142	3	38	abstract	abstract	NOUN
admet-142	3	39	the	the	DET
admet-142	3	40	aim	aim	NOUN
admet-142	3	41	of	of	ADP
admet-142	3	42	this	this	DET
admet-142	3	43	study	study	NOUN
admet-142	3	44	was	be	AUX
admet-142	3	45	to	to	PART
admet-142	3	46	evaluate	evaluate	VERB
admet-142	3	47	the	the	DET
admet-142	3	48	effects	effect	NOUN
admet-142	3	49	of	of	ADP
admet-142	3	50	the	the	DET
admet-142	3	51	mitogen	mitogen	NOUN
admet-142	3	52	-	-	PUNCT
admet-142	3	53	activated	activate	VERB
admet-142	3	54	protein	protein	NOUN
admet-142	3	55	kinase	kinase	NOUN
admet-142	3	56	(	(	PUNCT
admet-142	3	57	mapk	mapk	NOUN
admet-142	3	58	)	)	PUNCT
admet-142	3	59	pathway	pathway	NOUN
admet-142	3	60	inhibitors	inhibitor	NOUN
admet-142	3	61	sb203580	sb203580	PROPN
admet-142	3	62	,	,	PUNCT
admet-142	3	63	cmpd-1	cmpd-1	NUM
admet-142	3	64	,	,	PUNCT
admet-142	3	65	sb239063	sb239063	ADJ
admet-142	3	66	,	,	PUNCT
admet-142	3	67	sp600125	sp600125	PROPN
admet-142	3	68	,	,	PUNCT
admet-142	3	69	and	and	CCONJ
admet-142	3	70	fr180204	fr180204	PROPN
admet-142	3	71	on	on	ADP
admet-142	3	72	the	the	DET
admet-142	3	73	activity	activity	NOUN
admet-142	3	74	of	of	ADP
admet-142	3	75	p	p	NOUN
admet-142	3	76	-	-	PUNCT
admet-142	3	77	glycoprotein	glycoprotein	NOUN
admet-142	3	78	(	(	PUNCT
admet-142	3	79	p	p	NOUN
admet-142	3	80	-	-	PUNCT
admet-142	3	81	gp	gp	NOUN
admet-142	3	82	)	)	PUNCT
admet-142	3	83	and	and	CCONJ
admet-142	3	84	to	to	PART
admet-142	3	85	assess	assess	VERB
admet-142	3	86	whether	whether	SCONJ
admet-142	3	87	the	the	DET
admet-142	3	88	mapk	mapk	NOUN
admet-142	3	89	pathway	pathway	NOUN
admet-142	3	90	affects	affect	VERB
admet-142	3	91	p	p	NOUN
admet-142	3	92	-	-	PUNCT
admet-142	3	93	gp	gp	NOUN
admet-142	3	94	directly	directly	ADV
admet-142	3	95	.	.	PUNCT
admet-142	4	1	changes	change	NOUN
admet-142	4	2	in	in	ADP
admet-142	4	3	the	the	DET
admet-142	4	4	fluorescence	fluorescence	NOUN
admet-142	4	5	of	of	ADP
admet-142	4	6	residual	residual	ADJ
admet-142	4	7	rhodamine	rhodamine	NOUN
admet-142	4	8	123	123	NUM
admet-142	4	9	,	,	PUNCT
admet-142	4	10	a	a	DET
admet-142	4	11	marker	marker	NOUN
admet-142	4	12	of	of	ADP
admet-142	4	13	p	p	NOUN
admet-142	4	14	-	-	PUNCT
admet-142	4	15	gp	gp	NOUN
admet-142	4	16	activity	activity	NOUN
admet-142	4	17	,	,	PUNCT
admet-142	4	18	in	in	ADP
admet-142	4	19	the	the	DET
admet-142	4	20	apical	apical	ADJ
admet-142	4	21	region	region	NOUN
admet-142	4	22	of	of	ADP
admet-142	4	23	caco-2	caco-2	NUM
admet-142	4	24	cells	cell	NOUN
admet-142	4	25	were	be	AUX
admet-142	4	26	measured	measure	VERB
admet-142	4	27	in	in	ADP
admet-142	4	28	the	the	DET
admet-142	4	29	presence	presence	NOUN
admet-142	4	30	of	of	ADP
admet-142	4	31	mapk	mapk	NOUN
admet-142	4	32	pathway	pathway	NOUN
admet-142	4	33	inhibitors	inhibitor	NOUN
admet-142	4	34	using	use	VERB
admet-142	4	35	time	time	NOUN
admet-142	4	36	-	-	PUNCT
admet-142	4	37	lapse	lapse	NOUN
admet-142	4	38	confocal	confocal	ADJ
admet-142	4	39	laser	laser	NOUN
admet-142	4	40	scanning	scan	VERB
admet-142	4	41	microscopy	microscopy	NOUN
admet-142	4	42	at	at	ADP
admet-142	4	43	0	0	NUM
admet-142	4	44	,	,	PUNCT
admet-142	4	45	10	10	NUM
admet-142	4	46	,	,	PUNCT
admet-142	4	47	20	20	NUM
admet-142	4	48	,	,	PUNCT
admet-142	4	49	30	30	NUM
admet-142	4	50	,	,	PUNCT
admet-142	4	51	and	and	CCONJ
admet-142	5	1	60	60	NUM
admet-142	5	2	min	min	NOUN
admet-142	5	3	.	.	NOUN
admet-142	6	1	significant	significant	ADJ
admet-142	6	2	differences	difference	NOUN
admet-142	6	3	were	be	AUX
admet-142	6	4	observed	observe	VERB
admet-142	6	5	between	between	ADP
admet-142	6	6	the	the	DET
admet-142	6	7	fluorescence	fluorescence	NOUN
admet-142	6	8	levels	level	NOUN
admet-142	6	9	of	of	ADP
admet-142	6	10	control	control	NOUN
admet-142	6	11	cells	cell	NOUN
admet-142	6	12	and	and	CCONJ
admet-142	6	13	cells	cell	NOUN
admet-142	6	14	treated	treat	VERB
admet-142	6	15	with	with	ADP
admet-142	6	16	sb203580	sb203580	PROPN
admet-142	6	17	for	for	ADP
admet-142	6	18	20	20	NUM
admet-142	6	19	,	,	PUNCT
admet-142	6	20	30	30	NUM
admet-142	6	21	,	,	PUNCT
admet-142	6	22	or	or	CCONJ
admet-142	6	23	60	60	NUM
admet-142	6	24	min	min	NOUN
admet-142	6	25	.	.	PROPN
admet-142	7	1	however	however	ADV
admet-142	7	2	,	,	PUNCT
admet-142	7	3	no	no	DET
admet-142	7	4	significant	significant	ADJ
admet-142	7	5	change	change	NOUN
admet-142	7	6	was	be	AUX
admet-142	7	7	observed	observe	VERB
admet-142	7	8	in	in	ADP
admet-142	7	9	the	the	DET
admet-142	7	10	residual	residual	ADJ
admet-142	7	11	rhodamine	rhodamine	NOUN
admet-142	7	12	123	123	NUM
admet-142	7	13	fluorescence	fluorescence	NOUN
admet-142	7	14	of	of	ADP
admet-142	7	15	cells	cell	NOUN
admet-142	7	16	treated	treat	VERB
admet-142	7	17	with	with	ADP
admet-142	7	18	cmpd-1	cmpd-1	NUM
admet-142	7	19	,	,	PUNCT
admet-142	7	20	sb239063	sb239063	ADJ
admet-142	7	21	,	,	PUNCT
admet-142	7	22	sp600125	sp600125	PROPN
admet-142	7	23	,	,	PUNCT
admet-142	7	24	or	or	CCONJ
admet-142	7	25	fr180204	fr180204	PROPN
admet-142	7	26	.	.	PUNCT
admet-142	8	1	among	among	ADP
admet-142	8	2	the	the	DET
admet-142	8	3	p38	p38	NOUN
admet-142	8	4	-	-	PUNCT
admet-142	8	5	mapk	mapk	NOUN
admet-142	8	6	pathway	pathway	NOUN
admet-142	8	7	inhibitors	inhibitor	NOUN
admet-142	8	8	investigated	investigate	VERB
admet-142	8	9	,	,	PUNCT
admet-142	8	10	cmpd-1	cmpd-1	NUM
admet-142	8	11	and	and	CCONJ
admet-142	8	12	sb239063	sb239063	PROPN
admet-142	8	13	showed	show	VERB
admet-142	8	14	no	no	DET
admet-142	8	15	detectable	detectable	ADJ
admet-142	8	16	effect	effect	NOUN
admet-142	8	17	on	on	ADP
admet-142	8	18	the	the	DET
admet-142	8	19	activity	activity	NOUN
admet-142	8	20	of	of	ADP
admet-142	8	21	p	p	NOUN
admet-142	8	22	-	-	PUNCT
admet-142	8	23	gp	gp	NOUN
admet-142	8	24	.	.	PUNCT
admet-142	9	1	further	far	ADV
admet-142	9	2	,	,	PUNCT
admet-142	9	3	jnk	jnk	PROPN
admet-142	9	4	1	1	NUM
admet-142	9	5	,	,	PUNCT
admet-142	9	6	2	2	NUM
admet-142	9	7	,	,	PUNCT
admet-142	9	8	3	3	NUM
admet-142	9	9	-	-	PUNCT
admet-142	9	10	mapk	mapk	NOUN
admet-142	9	11	pathway	pathway	NOUN
admet-142	9	12	(	(	PUNCT
admet-142	9	13	sp600125	sp600125	PROPN
admet-142	9	14	)	)	PUNCT
admet-142	9	15	and	and	CCONJ
admet-142	9	16	erk1/2	erk1/2	PROPN
admet-142	9	17	pathway	pathway	NOUN
admet-142	9	18	(	(	PUNCT
admet-142	9	19	fr180204	fr180204	PROPN
admet-142	9	20	)	)	PUNCT
admet-142	9	21	inhibitors	inhibitor	NOUN
admet-142	9	22	did	do	AUX
admet-142	9	23	not	not	PART
admet-142	9	24	affect	affect	VERB
admet-142	9	25	p	p	NOUN
admet-142	9	26	-	-	PUNCT
admet-142	9	27	gp	gp	NOUN
admet-142	9	28	activity	activity	NOUN
admet-142	9	29	.	.	PUNCT
admet-142	10	1	however	however	ADV
admet-142	10	2	,	,	PUNCT
admet-142	10	3	sb203580	sb203580	PROPN
admet-142	10	4	enhanced	enhance	VERB
admet-142	10	5	the	the	DET
admet-142	10	6	transfer	transfer	NOUN
admet-142	10	7	of	of	ADP
admet-142	10	8	rhodamine	rhodamine	NOUN
admet-142	10	9	123	123	NUM
admet-142	10	10	across	across	ADP
admet-142	10	11	the	the	DET
admet-142	10	12	apical	apical	ADJ
admet-142	10	13	cell	cell	NOUN
admet-142	10	14	membrane	membrane	NOUN
admet-142	10	15	.	.	PUNCT
admet-142	11	1	thus	thus	ADV
admet-142	11	2	,	,	PUNCT
admet-142	11	3	sb203580	sb203580	PROPN
admet-142	11	4	activated	activate	VERB
admet-142	11	5	p	p	NOUN
admet-142	11	6	-	-	PUNCT
admet-142	11	7	gp	gp	NOUN
admet-142	11	8	,	,	PUNCT
admet-142	11	9	although	although	SCONJ
admet-142	11	10	not	not	PART
admet-142	11	11	through	through	ADP
admet-142	11	12	the	the	DET
admet-142	11	13	p38	p38	NOUN
admet-142	11	14	-	-	PUNCT
admet-142	11	15	mapk	mapk	NOUN
admet-142	11	16	pathway	pathway	NOUN
admet-142	11	17	.	.	PUNCT
admet-142	12	1	importantly	importantly	ADV
admet-142	12	2	,	,	PUNCT
admet-142	12	3	the	the	DET
admet-142	12	4	mapk	mapk	NOUN
admet-142	12	5	pathway	pathway	NOUN
admet-142	12	6	did	do	AUX
admet-142	12	7	not	not	PART
admet-142	12	8	affect	affect	VERB
admet-142	12	9	p	p	NOUN
admet-142	12	10	-	-	PUNCT
admet-142	12	11	gp	gp	NOUN
admet-142	12	12	activity	activity	NOUN
admet-142	12	13	shortly	shortly	ADV
admet-142	12	14	after	after	ADP
admet-142	12	15	treatment	treatment	NOUN
admet-142	12	16	.	.	PUNCT
admet-142	13	1	keywords	keyword	VERB
admet-142	13	2	confocal	confocal	ADJ
admet-142	13	3	laser	laser	NOUN
admet-142	13	4	scanning	scan	VERB
admet-142	13	5	microscopy	microscopy	NOUN
admet-142	13	6	;	;	PUNCT
admet-142	13	7	mapk	mapk	NOUN
admet-142	13	8	;	;	PUNCT
admet-142	13	9	sb203580	sb203580	PROPN
admet-142	13	10	introduction	introduction	NOUN
admet-142	13	11	p	p	NOUN
admet-142	13	12	-	-	PUNCT
admet-142	13	13	glycoprotein	glycoprotein	NOUN
admet-142	13	14	(	(	PUNCT
admet-142	13	15	p	p	NOUN
admet-142	13	16	-	-	PUNCT
admet-142	13	17	gp	gp	NOUN
admet-142	13	18	)	)	PUNCT
admet-142	13	19	is	be	AUX
admet-142	13	20	the	the	DET
admet-142	13	21	most	most	ADV
admet-142	13	22	thoroughly	thoroughly	ADV
admet-142	13	23	studied	study	VERB
admet-142	13	24	member	member	NOUN
admet-142	13	25	of	of	ADP
admet-142	13	26	the	the	DET
admet-142	13	27	adenosine	adenosine	ADJ
admet-142	13	28	triphosphate	triphosphate	NOUN
admet-142	13	29	-	-	PUNCT
admet-142	13	30	binding	bind	VERB
admet-142	13	31	cassette	cassette	NOUN
admet-142	13	32	transporter	transporter	NOUN
admet-142	13	33	superfamily	superfamily	ADV
admet-142	13	34	and	and	CCONJ
admet-142	13	35	is	be	AUX
admet-142	13	36	expressed	express	VERB
admet-142	13	37	throughout	throughout	ADP
admet-142	13	38	the	the	DET
admet-142	13	39	intestinal	intestinal	ADJ
admet-142	13	40	epithelium	epithelium	NOUN
admet-142	13	41	,	,	PUNCT
admet-142	13	42	hepatocytes	hepatocyte	NOUN
admet-142	13	43	,	,	PUNCT
admet-142	13	44	renal	renal	ADJ
admet-142	13	45	tubular	tubular	ADJ
admet-142	13	46	cells	cell	NOUN
admet-142	13	47	,	,	PUNCT
admet-142	13	48	and	and	CCONJ
admet-142	13	49	the	the	DET
admet-142	13	50	blood	blood	NOUN
admet-142	13	51	-	-	PUNCT
admet-142	13	52	brain	brain	NOUN
admet-142	13	53	barrier	barrier	NOUN
admet-142	13	54	[	[	X
admet-142	13	55	1	1	NUM
admet-142	13	56	]	]	PUNCT
admet-142	13	57	.	.	PUNCT
admet-142	14	1	p	p	X
admet-142	14	2	-	-	PUNCT
admet-142	14	3	gp	gp	NOUN
admet-142	14	4	is	be	AUX
admet-142	14	5	encoded	encode	VERB
admet-142	14	6	by	by	ADP
admet-142	14	7	the	the	DET
admet-142	14	8	abcb1	abcb1	PROPN
admet-142	14	9	/	/	SYM
admet-142	14	10	mdr1	mdr1	PROPN
admet-142	14	11	gene	gene	NOUN
admet-142	14	12	in	in	ADP
admet-142	14	13	humans	human	NOUN
admet-142	14	14	[	[	X
admet-142	14	15	2	2	NUM
admet-142	14	16	]	]	PUNCT
admet-142	14	17	.	.	PUNCT
admet-142	15	1	because	because	SCONJ
admet-142	15	2	of	of	ADP
admet-142	15	3	its	its	PRON
admet-142	15	4	ubiquitous	ubiquitous	ADJ
admet-142	15	5	expression	expression	NOUN
admet-142	15	6	and	and	CCONJ
admet-142	15	7	broad	broad	ADJ
admet-142	15	8	specificity	specificity	NOUN
admet-142	15	9	,	,	PUNCT
admet-142	15	10	changes	change	NOUN
admet-142	15	11	in	in	ADP
admet-142	15	12	p	p	NOUN
admet-142	15	13	-	-	PUNCT
admet-142	15	14	gp	gp	NOUN
admet-142	15	15	expression	expression	NOUN
admet-142	15	16	or	or	CCONJ
admet-142	15	17	efflux	efflux	NOUN
admet-142	15	18	activity	activity	NOUN
admet-142	15	19	induced	induce	VERB
admet-142	15	20	by	by	ADP
admet-142	15	21	drug	drug	NOUN
admet-142	15	22	treatments	treatment	NOUN
admet-142	15	23	,	,	PUNCT
admet-142	15	24	diet	diet	NOUN
admet-142	15	25	,	,	PUNCT
admet-142	15	26	environmental	environmental	ADJ
admet-142	15	27	factors	factor	NOUN
admet-142	15	28	,	,	PUNCT
admet-142	15	29	or	or	CCONJ
admet-142	15	30	single	single	ADJ
admet-142	15	31	nucleotide	nucleotide	ADJ
admet-142	15	32	polymorphisms	polymorphism	NOUN
admet-142	15	33	(	(	PUNCT
admet-142	15	34	snps	snps	PROPN
admet-142	15	35	)	)	PUNCT
admet-142	15	36	can	can	AUX
admet-142	15	37	greatly	greatly	ADV
admet-142	15	38	affect	affect	VERB
admet-142	15	39	drug	drug	NOUN
admet-142	15	40	disposition	disposition	NOUN
admet-142	15	41	,	,	PUNCT
admet-142	15	42	pharmacokinetics	pharmacokinetic	NOUN
admet-142	15	43	,	,	PUNCT
admet-142	15	44	and	and	CCONJ
admet-142	15	45	clinical	clinical	ADJ
admet-142	15	46	response	response	NOUN
admet-142	16	1	[	[	X
admet-142	16	2	3	3	NUM
admet-142	16	3	]	]	PUNCT
admet-142	16	4	.	.	PUNCT
admet-142	17	1	hence	hence	ADV
admet-142	17	2	,	,	PUNCT
admet-142	17	3	identification	identification	NOUN
admet-142	17	4	of	of	ADP
admet-142	17	5	p	p	NOUN
admet-142	17	6	-	-	PUNCT
admet-142	17	7	gp	gp	NOUN
admet-142	17	8	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-142	17	9	mailto:wakuda@mukogawa-u.ac.jp	mailto:wakuda@mukogawa-u.ac.jp	PROPN
admet-142	17	10	wakuda	wakuda	PROPN
admet-142	17	11	et	et	PROPN
admet-142	17	12	al	al	PROPN
admet-142	17	13	.	.	PROPN
admet-142	17	14	admet	admet	PROPN
admet-142	17	15	&	&	CCONJ
admet-142	17	16	dmpk	dmpk	PROPN
admet-142	17	17	3(1	3(1	NUM
admet-142	17	18	)	)	PUNCT
admet-142	17	19	(	(	PUNCT
admet-142	17	20	2015	2015	NUM
admet-142	17	21	)	)	PUNCT
admet-142	17	22	77	77	NUM
admet-142	17	23	-	-	SYM
admet-142	17	24	83	83	NUM
admet-142	17	25	78	78	NUM
admet-142	17	26	figure	figure	NOUN
admet-142	17	27	1	1	NUM
admet-142	17	28	.	.	PUNCT
admet-142	18	1	the	the	DET
admet-142	18	2	mapk	mapk	NOUN
admet-142	18	3	pathway	pathway	NOUN
admet-142	18	4	substrates	substrate	NOUN
admet-142	18	5	is	be	AUX
admet-142	18	6	important	important	ADJ
admet-142	18	7	for	for	ADP
admet-142	18	8	therapeutic	therapeutic	ADJ
admet-142	18	9	optimization	optimization	NOUN
admet-142	18	10	and	and	CCONJ
admet-142	18	11	to	to	PART
admet-142	18	12	avoid	avoid	VERB
admet-142	18	13	drug	drug	NOUN
admet-142	18	14	-	-	PUNCT
admet-142	18	15	drug	drug	NOUN
admet-142	18	16	interactions	interaction	NOUN
admet-142	18	17	.	.	PUNCT
admet-142	19	1	however	however	ADV
admet-142	19	2	,	,	PUNCT
admet-142	19	3	little	little	ADJ
admet-142	19	4	is	be	AUX
admet-142	19	5	known	know	VERB
admet-142	19	6	of	of	ADP
admet-142	19	7	p	p	NOUN
admet-142	19	8	-	-	PUNCT
admet-142	19	9	gp	gp	NOUN
admet-142	19	10	regulation	regulation	NOUN
admet-142	19	11	.	.	PUNCT
admet-142	20	1	mitogen	mitogen	NOUN
admet-142	20	2	-	-	PUNCT
admet-142	20	3	activated	activate	VERB
admet-142	20	4	protein	protein	NOUN
admet-142	20	5	kinases	kinase	NOUN
admet-142	20	6	(	(	PUNCT
admet-142	20	7	mapks	mapks	NOUN
admet-142	20	8	)	)	PUNCT
admet-142	20	9	are	be	AUX
admet-142	20	10	a	a	DET
admet-142	20	11	family	family	NOUN
admet-142	20	12	of	of	ADP
admet-142	20	13	ser	ser	PROPN
admet-142	20	14	/	/	SYM
admet-142	20	15	thr	thr	PROPN
admet-142	20	16	protein	protein	NOUN
admet-142	20	17	kinases	kinase	NOUN
admet-142	20	18	that	that	PRON
admet-142	20	19	are	be	AUX
admet-142	20	20	widely	widely	ADV
admet-142	20	21	conserved	conserve	VERB
admet-142	20	22	among	among	ADP
admet-142	20	23	eukaryotes	eukaryote	NOUN
admet-142	20	24	and	and	CCONJ
admet-142	20	25	are	be	AUX
admet-142	20	26	involved	involve	VERB
admet-142	20	27	in	in	ADP
admet-142	20	28	many	many	ADJ
admet-142	20	29	cellular	cellular	ADJ
admet-142	20	30	functions	function	NOUN
admet-142	20	31	.	.	PUNCT
admet-142	21	1	the	the	DET
admet-142	21	2	p38	p38	NOUN
admet-142	21	3	-	-	PUNCT
admet-142	21	4	mapk	mapk	NOUN
admet-142	21	5	and	and	CCONJ
admet-142	21	6	c	c	PROPN
admet-142	21	7	-	-	PUNCT
admet-142	21	8	jun	jun	PROPN
admet-142	21	9	nterminal	nterminal	PROPN
admet-142	21	10	kinase	kinase	PROPN
admet-142	21	11	(	(	PUNCT
admet-142	21	12	jnk)-mapk	jnk)-mapk	PROPN
admet-142	21	13	signalling	signal	VERB
admet-142	21	14	pathways	pathway	NOUN
admet-142	21	15	allow	allow	VERB
admet-142	21	16	cells	cell	NOUN
admet-142	21	17	to	to	PART
admet-142	21	18	interpret	interpret	VERB
admet-142	21	19	a	a	DET
admet-142	21	20	wide	wide	ADJ
admet-142	21	21	range	range	NOUN
admet-142	21	22	of	of	ADP
admet-142	21	23	external	external	ADJ
admet-142	21	24	signals	signal	NOUN
admet-142	21	25	and	and	CCONJ
admet-142	21	26	respond	respond	VERB
admet-142	21	27	appropriately	appropriately	ADV
admet-142	21	28	by	by	ADP
admet-142	21	29	generating	generate	VERB
admet-142	21	30	a	a	DET
admet-142	21	31	plethora	plethora	NOUN
admet-142	21	32	of	of	ADP
admet-142	21	33	different	different	ADJ
admet-142	21	34	biological	biological	ADJ
admet-142	21	35	effects	effect	NOUN
admet-142	21	36	.	.	PUNCT
admet-142	22	1	there	there	PRON
admet-142	22	2	are	be	VERB
admet-142	22	3	four	four	NUM
admet-142	22	4	p38	p38	NOUN
admet-142	22	5	subtypes	subtype	NOUN
admet-142	22	6	(	(	PUNCT
admet-142	22	7	p38α	p38α	NOUN
admet-142	22	8	,	,	PUNCT
admet-142	22	9	p38β	p38β	ADV
admet-142	22	10	,	,	PUNCT
admet-142	22	11	p38γ	p38γ	NOUN
admet-142	22	12	,	,	PUNCT
admet-142	22	13	p38δ	p38δ	PRON
admet-142	22	14	)	)	PUNCT
admet-142	22	15	and	and	CCONJ
admet-142	22	16	three	three	NUM
admet-142	22	17	jnk	jnk	PROPN
admet-142	22	18	subtypes	subtype	NOUN
admet-142	22	19	(	(	PUNCT
admet-142	22	20	jnk1	jnk1	PROPN
admet-142	22	21	,	,	PUNCT
admet-142	22	22	jnk2	jnk2	PROPN
admet-142	22	23	,	,	PUNCT
admet-142	22	24	jnk3	jnk3	PROPN
admet-142	22	25	)	)	PUNCT
admet-142	23	1	[	[	X
admet-142	23	2	4,5	4,5	NUM
admet-142	23	3	]	]	PUNCT
admet-142	23	4	.	.	PUNCT
admet-142	24	1	the	the	DET
admet-142	24	2	extracellular	extracellular	ADJ
admet-142	24	3	signalregulated	signalregulate	VERB
admet-142	24	4	kinase	kinase	NOUN
admet-142	24	5	(	(	PUNCT
admet-142	24	6	erk1/2)-mapk	erk1/2)-mapk	NOUN
admet-142	24	7	signalling	signal	VERB
admet-142	24	8	pathway	pathway	NOUN
admet-142	24	9	can	can	AUX
admet-142	24	10	be	be	AUX
admet-142	24	11	activated	activate	VERB
admet-142	24	12	in	in	ADP
admet-142	24	13	response	response	NOUN
admet-142	24	14	to	to	ADP
admet-142	24	15	a	a	DET
admet-142	24	16	diverse	diverse	ADJ
admet-142	24	17	range	range	NOUN
admet-142	24	18	of	of	ADP
admet-142	24	19	extracellular	extracellular	ADJ
admet-142	24	20	stimuli	stimulus	NOUN
admet-142	24	21	,	,	PUNCT
admet-142	24	22	including	include	VERB
admet-142	24	23	mitogens	mitogen	NOUN
admet-142	24	24	,	,	PUNCT
admet-142	24	25	growth	growth	NOUN
admet-142	24	26	factors	factor	NOUN
admet-142	24	27	,	,	PUNCT
admet-142	24	28	and	and	CCONJ
admet-142	24	29	cytokines	cytokine	NOUN
admet-142	24	30	(	(	PUNCT
admet-142	24	31	fig	fig	NOUN
admet-142	24	32	.	.	NOUN
admet-142	25	1	1	1	NUM
admet-142	25	2	)	)	PUNCT
admet-142	26	1	[	[	X
admet-142	26	2	6	6	NUM
admet-142	26	3	]	]	PUNCT
admet-142	26	4	.	.	PUNCT
admet-142	27	1	several	several	ADJ
admet-142	27	2	studies	study	NOUN
admet-142	27	3	have	have	AUX
admet-142	27	4	indicated	indicate	VERB
admet-142	27	5	that	that	SCONJ
admet-142	27	6	mapk	mapk	NOUN
admet-142	27	7	signalling	signal	VERB
admet-142	27	8	pathways	pathway	NOUN
admet-142	27	9	may	may	AUX
admet-142	27	10	regulate	regulate	VERB
admet-142	27	11	membrane	membrane	ADJ
admet-142	27	12	trafficking	trafficking	NOUN
admet-142	27	13	proteins	protein	NOUN
admet-142	27	14	.	.	PUNCT
admet-142	28	1	for	for	ADP
admet-142	28	2	example	example	NOUN
admet-142	28	3	,	,	PUNCT
admet-142	28	4	fujishiro	fujishiro	NOUN
admet-142	28	5	et	et	PROPN
admet-142	28	6	al	al	PROPN
admet-142	28	7	.	.	PROPN
admet-142	28	8	reported	report	VERB
admet-142	28	9	that	that	SCONJ
admet-142	28	10	activation	activation	NOUN
admet-142	28	11	of	of	ADP
admet-142	28	12	the	the	DET
admet-142	28	13	p38	p38	NOUN
admet-142	28	14	-	-	PUNCT
admet-142	28	15	mapk	mapk	NOUN
admet-142	28	16	pathway	pathway	NOUN
admet-142	28	17	is	be	AUX
admet-142	28	18	not	not	PART
admet-142	28	19	necessary	necessary	ADJ
admet-142	28	20	for	for	SCONJ
admet-142	28	21	insulin	insulin	NOUN
admet-142	28	22	-	-	PUNCT
admet-142	28	23	induced	induce	VERB
admet-142	28	24	glucose	glucose	NOUN
admet-142	28	25	uptake	uptake	NOUN
admet-142	28	26	but	but	CCONJ
admet-142	28	27	that	that	SCONJ
admet-142	28	28	it	it	PRON
admet-142	28	29	regulates	regulate	VERB
admet-142	28	30	glucose	glucose	NOUN
admet-142	28	31	transporter	transporter	NOUN
admet-142	28	32	expression	expression	NOUN
admet-142	28	33	[	[	X
admet-142	28	34	7	7	NUM
admet-142	28	35	]	]	PUNCT
admet-142	28	36	.	.	PUNCT
admet-142	29	1	nagelin	nagelin	PROPN
admet-142	29	2	et	et	PROPN
admet-142	29	3	al	al	PROPN
admet-142	29	4	.	.	PROPN
admet-142	29	5	reported	report	VERB
admet-142	29	6	that	that	PRON
admet-142	29	7	murine	murine	ADJ
admet-142	29	8	12/15	12/15	NUM
admet-142	29	9	-	-	PUNCT
admet-142	29	10	lipoxygenase	lipoxygenase	NOUN
admet-142	29	11	regulates	regulate	VERB
admet-142	29	12	the	the	DET
admet-142	29	13	expression	expression	NOUN
admet-142	29	14	and	and	CCONJ
admet-142	29	15	function	function	NOUN
admet-142	29	16	of	of	ADP
admet-142	29	17	the	the	DET
admet-142	29	18	atp	atp	NOUN
admet-142	29	19	-	-	PUNCT
admet-142	29	20	binding	bind	VERB
admet-142	29	21	cassette	cassette	NOUN
admet-142	29	22	transporter	transporter	NOUN
admet-142	29	23	g1	g1	NOUN
admet-142	29	24	through	through	ADP
admet-142	29	25	p38and	p38and	PROPN
admet-142	29	26	jnk2	jnk2	NOUN
admet-142	29	27	-	-	PUNCT
admet-142	29	28	dependent	dependent	ADJ
admet-142	29	29	pathways	pathway	NOUN
admet-142	30	1	[	[	X
admet-142	30	2	8	8	NUM
admet-142	30	3	]	]	PUNCT
admet-142	30	4	.	.	PUNCT
admet-142	31	1	these	these	DET
admet-142	31	2	reports	report	NOUN
admet-142	31	3	suggest	suggest	VERB
admet-142	31	4	that	that	SCONJ
admet-142	31	5	the	the	DET
admet-142	31	6	mapk	mapk	NOUN
admet-142	31	7	pathway	pathway	NOUN
admet-142	31	8	transmits	transmit	VERB
admet-142	31	9	signals	signal	NOUN
admet-142	31	10	to	to	ADP
admet-142	31	11	membrane	membrane	NOUN
admet-142	31	12	trafficking	trafficking	NOUN
admet-142	31	13	proteins	protein	NOUN
admet-142	31	14	to	to	PART
admet-142	31	15	regulate	regulate	VERB
admet-142	31	16	their	their	PRON
admet-142	31	17	activity	activity	NOUN
admet-142	31	18	.	.	PUNCT
admet-142	32	1	in	in	ADP
admet-142	32	2	the	the	DET
admet-142	32	3	present	present	ADJ
admet-142	32	4	study	study	NOUN
admet-142	32	5	,	,	PUNCT
admet-142	32	6	we	we	PRON
admet-142	32	7	evaluated	evaluate	VERB
admet-142	32	8	the	the	DET
admet-142	32	9	effects	effect	NOUN
admet-142	32	10	of	of	ADP
admet-142	32	11	mapk	mapk	NOUN
admet-142	32	12	pathway	pathway	NOUN
admet-142	32	13	inhibitors	inhibitor	NOUN
admet-142	32	14	(	(	PUNCT
admet-142	32	15	sb203580	sb203580	PROPN
admet-142	32	16	,	,	PUNCT
admet-142	32	17	competitive	competitive	ADJ
admet-142	32	18	p38α	p38α	NOUN
admet-142	32	19	and	and	CCONJ
admet-142	32	20	β	β	NOUN
admet-142	32	21	inhibitor	inhibitor	NOUN
admet-142	32	22	;	;	PUNCT
admet-142	32	23	cmpd-1	cmpd-1	NUM
admet-142	32	24	,	,	PUNCT
admet-142	32	25	non	non	ADJ
admet-142	32	26	-	-	ADJ
admet-142	32	27	competitive	competitive	ADJ
admet-142	32	28	p38α	p38α	NOUN
admet-142	32	29	inhibitor	inhibitor	NOUN
admet-142	32	30	;	;	PUNCT
admet-142	32	31	sb239063	sb239063	ADJ
admet-142	32	32	,	,	PUNCT
admet-142	32	33	competitive	competitive	ADJ
admet-142	32	34	p38α	p38α	NOUN
admet-142	32	35	and	and	CCONJ
admet-142	32	36	β	β	X
admet-142	32	37	specific	specific	ADJ
admet-142	32	38	inhibitor	inhibitor	NOUN
admet-142	32	39	;	;	PUNCT
admet-142	32	40	sp600125	sp600125	PROPN
admet-142	32	41	,	,	PUNCT
admet-142	32	42	competitive	competitive	ADJ
admet-142	32	43	jnk	jnk	PROPN
admet-142	32	44	1	1	NUM
admet-142	32	45	,	,	PUNCT
admet-142	32	46	2	2	NUM
admet-142	32	47	,	,	PUNCT
admet-142	32	48	3	3	NUM
admet-142	32	49	inhibitor	inhibitor	NOUN
admet-142	32	50	;	;	PUNCT
admet-142	32	51	fr180204	fr180204	PROPN
admet-142	32	52	,	,	PUNCT
admet-142	32	53	competitive	competitive	ADJ
admet-142	32	54	erk1/2	erk1/2	NOUN
admet-142	32	55	inhibitor	inhibitor	NOUN
admet-142	32	56	)	)	PUNCT
admet-142	32	57	on	on	ADP
admet-142	32	58	the	the	DET
admet-142	32	59	admet	admet	PROPN
admet-142	32	60	&	&	CCONJ
admet-142	32	61	dmpk	dmpk	PROPN
admet-142	32	62	3(1	3(1	NUM
admet-142	32	63	)	)	PUNCT
admet-142	32	64	(	(	PUNCT
admet-142	32	65	2015	2015	NUM
admet-142	32	66	)	)	PUNCT
admet-142	32	67	77	77	NUM
admet-142	32	68	-	-	SYM
admet-142	32	69	83	83	NUM
admet-142	32	70	mitogen	mitogen	NOUN
admet-142	32	71	-	-	PUNCT
admet-142	32	72	activated	activate	VERB
admet-142	32	73	protein	protein	NOUN
admet-142	32	74	kinase	kinase	NOUN
admet-142	32	75	pathway	pathway	NOUN
admet-142	32	76	inhibitors	inhibitor	NOUN
admet-142	32	77	doi	doi	VERB
admet-142	32	78	:	:	PUNCT
admet-142	32	79	10.5599	10.5599	NUM
admet-142	32	80	/	/	SYM
admet-142	32	81	admet.3.1.142	admet.3.1.142	PROPN
admet-142	32	82	79	79	NUM
admet-142	32	83	activity	activity	NOUN
admet-142	32	84	of	of	ADP
admet-142	32	85	p	p	NOUN
admet-142	32	86	-	-	PUNCT
admet-142	32	87	gp	gp	NOUN
admet-142	32	88	using	use	VERB
admet-142	32	89	time	time	NOUN
admet-142	32	90	-	-	PUNCT
admet-142	32	91	lapse	lapse	NOUN
admet-142	32	92	confocal	confocal	ADJ
admet-142	32	93	laser	laser	NOUN
admet-142	32	94	scanning	scan	VERB
admet-142	32	95	microscopy	microscopy	NOUN
admet-142	32	96	.	.	PUNCT
admet-142	33	1	the	the	DET
admet-142	33	2	confocal	confocal	ADJ
admet-142	33	3	laser	laser	NOUN
admet-142	33	4	scanning	scan	VERB
admet-142	33	5	microscopy	microscopy	NOUN
admet-142	33	6	-	-	PUNCT
admet-142	33	7	based	base	VERB
admet-142	33	8	assay	assay	NOUN
admet-142	33	9	was	be	AUX
admet-142	33	10	used	use	VERB
admet-142	33	11	to	to	PART
admet-142	33	12	measure	measure	VERB
admet-142	33	13	residual	residual	ADJ
admet-142	33	14	rhodamine	rhodamine	NOUN
admet-142	33	15	123	123	NUM
admet-142	33	16	in	in	ADP
admet-142	33	17	the	the	DET
admet-142	33	18	apical	apical	ADJ
admet-142	33	19	region	region	NOUN
admet-142	33	20	of	of	ADP
admet-142	33	21	caco-2	caco-2	NUM
admet-142	33	22	cells	cell	NOUN
admet-142	33	23	;	;	PUNCT
admet-142	33	24	this	this	DET
admet-142	33	25	method	method	NOUN
admet-142	33	26	is	be	AUX
admet-142	33	27	more	more	ADV
admet-142	33	28	sensitive	sensitive	ADJ
admet-142	33	29	than	than	ADP
admet-142	33	30	conventional	conventional	ADJ
admet-142	33	31	methods	method	NOUN
admet-142	33	32	that	that	PRON
admet-142	33	33	rely	rely	VERB
admet-142	33	34	on	on	ADP
admet-142	33	35	microplate	microplate	NOUN
admet-142	33	36	readers	reader	NOUN
admet-142	33	37	and	and	CCONJ
admet-142	33	38	fluorescence	fluorescence	NOUN
admet-142	33	39	microscopy	microscopy	NOUN
admet-142	33	40	[	[	X
admet-142	33	41	9,10	9,10	NUM
admet-142	33	42	]	]	X
admet-142	33	43	.	.	PUNCT
admet-142	34	1	experimental	experimental	ADJ
admet-142	34	2	materials	material	NOUN
admet-142	34	3	sb203580	sb203580	PROPN
admet-142	34	4	was	be	AUX
admet-142	34	5	obtained	obtain	VERB
admet-142	34	6	from	from	ADP
admet-142	34	7	invivogen	invivogen	PROPN
admet-142	34	8	(	(	PUNCT
admet-142	34	9	san	san	PROPN
admet-142	34	10	diego	diego	PROPN
admet-142	34	11	,	,	PUNCT
admet-142	34	12	ca	ca	PROPN
admet-142	34	13	,	,	PUNCT
admet-142	34	14	u.s.a	u.s.a	PROPN
admet-142	34	15	.	.	PUNCT
admet-142	34	16	)	)	PUNCT
admet-142	34	17	.	.	PUNCT
admet-142	35	1	cmpd-1	cmpd-1	PRON
admet-142	35	2	was	be	AUX
admet-142	35	3	obtained	obtain	VERB
admet-142	35	4	from	from	ADP
admet-142	35	5	tocris	tocris	PROPN
admet-142	35	6	bioscience	bioscience	PROPN
admet-142	35	7	(	(	PUNCT
admet-142	35	8	ellisville	ellisville	PROPN
admet-142	35	9	,	,	PUNCT
admet-142	35	10	mo	mo	PROPN
admet-142	35	11	,	,	PUNCT
admet-142	35	12	u.s.a	u.s.a	PROPN
admet-142	35	13	.	.	PUNCT
admet-142	35	14	)	)	PUNCT
admet-142	35	15	.	.	PUNCT
admet-142	36	1	sb239063	sb239063	PROPN
admet-142	36	2	was	be	AUX
admet-142	36	3	obtained	obtain	VERB
admet-142	36	4	from	from	ADP
admet-142	36	5	sigma	sigma	PROPN
admet-142	36	6	-	-	PUNCT
admet-142	36	7	aldrich	aldrich	PROPN
admet-142	36	8	(	(	PUNCT
admet-142	36	9	st	st	PROPN
admet-142	36	10	.	.	PROPN
admet-142	36	11	louis	louis	PROPN
admet-142	36	12	,	,	PUNCT
admet-142	36	13	mo	mo	PROPN
admet-142	36	14	,	,	PUNCT
admet-142	36	15	u.s.a	u.s.a	PROPN
admet-142	36	16	.	.	PUNCT
admet-142	36	17	)	)	PUNCT
admet-142	36	18	.	.	PUNCT
admet-142	37	1	sp600125	sp600125	PROPN
admet-142	37	2	was	be	AUX
admet-142	37	3	obtained	obtain	VERB
admet-142	37	4	from	from	ADP
admet-142	37	5	cayman	cayman	PROPN
admet-142	37	6	chemical	chemical	PROPN
admet-142	37	7	(	(	PUNCT
admet-142	37	8	ann	ann	PROPN
admet-142	37	9	arbor	arbor	PROPN
admet-142	37	10	,	,	PUNCT
admet-142	37	11	mi	mi	PROPN
admet-142	37	12	,	,	PUNCT
admet-142	37	13	u.s.a	u.s.a	NOUN
admet-142	37	14	.	.	PUNCT
admet-142	37	15	)	)	PUNCT
admet-142	37	16	.	.	PUNCT
admet-142	38	1	fr180204	fr180204	PROPN
admet-142	38	2	was	be	AUX
admet-142	38	3	obtained	obtain	VERB
admet-142	38	4	from	from	ADP
admet-142	38	5	santa	santa	PROPN
admet-142	38	6	cruz	cruz	PROPN
admet-142	38	7	biotechnology	biotechnology	PROPN
admet-142	38	8	(	(	PUNCT
admet-142	38	9	santa	santa	PROPN
admet-142	38	10	cruz	cruz	PROPN
admet-142	38	11	,	,	PUNCT
admet-142	38	12	ca	ca	PROPN
admet-142	38	13	,	,	PUNCT
admet-142	38	14	u.s.a	u.s.a	PROPN
admet-142	38	15	.	.	PUNCT
admet-142	38	16	)	)	PUNCT
admet-142	38	17	.	.	PUNCT
admet-142	39	1	rhodamine	rhodamine	NOUN
admet-142	39	2	123	123	NUM
admet-142	39	3	was	be	AUX
admet-142	39	4	obtained	obtain	VERB
admet-142	39	5	from	from	ADP
admet-142	39	6	molecular	molecular	ADJ
admet-142	39	7	probes	probe	NOUN
admet-142	39	8	(	(	PUNCT
admet-142	39	9	eugene	eugene	NOUN
admet-142	39	10	,	,	PUNCT
admet-142	39	11	or	or	CCONJ
admet-142	39	12	,	,	PUNCT
admet-142	39	13	u.s.a	u.s.a	PROPN
admet-142	39	14	.	.	PUNCT
admet-142	39	15	)	)	PUNCT
admet-142	39	16	.	.	PUNCT
admet-142	40	1	cell	cell	NOUN
admet-142	40	2	culture	culture	NOUN
admet-142	40	3	of	of	ADP
admet-142	40	4	caco-2	caco-2	NUM
admet-142	40	5	cells	cell	NOUN
admet-142	40	6	the	the	DET
admet-142	40	7	human	human	ADJ
admet-142	40	8	colon	colon	NOUN
admet-142	40	9	adenocarcinoma	adenocarcinoma	NOUN
admet-142	40	10	cell	cell	NOUN
admet-142	40	11	line	line	NOUN
admet-142	40	12	(	(	PUNCT
admet-142	40	13	caco-2	caco-2	NOUN
admet-142	40	14	)	)	PUNCT
admet-142	40	15	was	be	AUX
admet-142	40	16	purchased	purchase	VERB
admet-142	40	17	from	from	ADP
admet-142	40	18	ds	ds	ADJ
admet-142	40	19	pharma	pharma	PROPN
admet-142	40	20	biomedical	biomedical	NOUN
admet-142	40	21	(	(	PUNCT
admet-142	40	22	osaka	osaka	PROPN
admet-142	40	23	,	,	PUNCT
admet-142	40	24	japan	japan	PROPN
admet-142	40	25	)	)	PUNCT
admet-142	40	26	.	.	PUNCT
admet-142	41	1	the	the	DET
admet-142	41	2	cells	cell	NOUN
admet-142	41	3	were	be	AUX
admet-142	41	4	used	use	VERB
admet-142	41	5	for	for	ADP
admet-142	41	6	experiments	experiment	NOUN
admet-142	41	7	7	7	NUM
admet-142	41	8	d	d	NOUN
admet-142	41	9	after	after	ADP
admet-142	41	10	seeding	seed	VERB
admet-142	41	11	and	and	CCONJ
admet-142	41	12	between	between	ADP
admet-142	41	13	passages	passage	NOUN
admet-142	41	14	47	47	NUM
admet-142	41	15	and	and	CCONJ
admet-142	41	16	52	52	NUM
admet-142	41	17	.	.	PUNCT
admet-142	42	1	figure	figure	NOUN
admet-142	42	2	2	2	NUM
admet-142	42	3	.	.	PUNCT
admet-142	43	1	the	the	DET
admet-142	43	2	protocol	protocol	NOUN
admet-142	43	3	for	for	ADP
admet-142	43	4	measurement	measurement	NOUN
admet-142	43	5	of	of	ADP
admet-142	43	6	p	p	NOUN
admet-142	43	7	-	-	PUNCT
admet-142	43	8	glycoprotein	glycoprotein	NOUN
admet-142	43	9	-	-	PUNCT
admet-142	43	10	mediated	mediate	VERB
admet-142	43	11	transport	transport	NOUN
admet-142	43	12	activity	activity	NOUN
admet-142	43	13	using	use	VERB
admet-142	43	14	confocal	confocal	ADJ
admet-142	43	15	laser	laser	NOUN
admet-142	43	16	-	-	PUNCT
admet-142	43	17	scanning	scanning	NOUN
admet-142	43	18	microscopy	microscopy	NOUN
admet-142	43	19	in	in	ADP
admet-142	43	20	the	the	DET
admet-142	43	21	presence	presence	NOUN
admet-142	43	22	or	or	CCONJ
admet-142	43	23	absence	absence	NOUN
admet-142	43	24	of	of	ADP
admet-142	43	25	inhibitor	inhibitor	NOUN
admet-142	43	26	agents	agent	NOUN
admet-142	43	27	.	.	PUNCT
admet-142	44	1	quantification	quantification	NOUN
admet-142	44	2	of	of	ADP
admet-142	44	3	rhodamine	rhodamine	NOUN
admet-142	44	4	123	123	NUM
admet-142	44	5	by	by	ADP
admet-142	44	6	time	time	NOUN
admet-142	44	7	-	-	PUNCT
admet-142	44	8	lapse	lapse	NOUN
admet-142	44	9	confocal	confocal	ADJ
admet-142	44	10	laser	laser	NOUN
admet-142	44	11	scanning	scan	VERB
admet-142	44	12	microscopy	microscopy	NOUN
admet-142	44	13	transport	transport	NOUN
admet-142	44	14	measurements	measurement	NOUN
admet-142	44	15	were	be	AUX
admet-142	44	16	performed	perform	VERB
admet-142	44	17	in	in	ADP
admet-142	44	18	a	a	DET
admet-142	44	19	transwell	transwell	NOUN
admet-142	44	20	chamber	chamber	NOUN
admet-142	44	21	(	(	PUNCT
admet-142	44	22	bd	bd	PROPN
admet-142	44	23	biosciences	bioscience	NOUN
admet-142	44	24	,	,	PUNCT
admet-142	44	25	san	san	PROPN
admet-142	44	26	jose	jose	PROPN
admet-142	44	27	,	,	PUNCT
admet-142	44	28	ca	ca	PROPN
admet-142	44	29	,	,	PUNCT
admet-142	44	30	u.s.a	u.s.a	PROPN
admet-142	44	31	.	.	PUNCT
admet-142	44	32	)	)	PUNCT
admet-142	44	33	.	.	PUNCT
admet-142	45	1	caco-2	caco-2	NUM
admet-142	45	2	cells	cell	NOUN
admet-142	45	3	were	be	AUX
admet-142	45	4	seeded	seed	VERB
admet-142	45	5	at	at	ADP
admet-142	45	6	a	a	DET
admet-142	45	7	density	density	NOUN
admet-142	45	8	of	of	ADP
admet-142	45	9	3	3	NUM
admet-142	45	10	×	×	NOUN
admet-142	45	11	104	104	NUM
admet-142	45	12	cells	cell	NOUN
admet-142	45	13	per	per	ADP
admet-142	45	14	filter	filter	NOUN
admet-142	45	15	on	on	ADP
admet-142	45	16	polyethylene	polyethylene	NOUN
admet-142	45	17	terephthalate	terephthalate	NOUN
admet-142	45	18	filters	filter	NOUN
admet-142	45	19	in	in	ADP
admet-142	45	20	the	the	DET
admet-142	45	21	cell	cell	NOUN
admet-142	45	22	culture	culture	NOUN
admet-142	45	23	inserts	insert	NOUN
admet-142	45	24	.	.	PUNCT
admet-142	46	1	the	the	DET
admet-142	46	2	cell	cell	NOUN
admet-142	46	3	culture	culture	NOUN
admet-142	46	4	inserts	insert	NOUN
admet-142	46	5	were	be	AUX
admet-142	46	6	placed	place	VERB
admet-142	46	7	on	on	ADP
admet-142	46	8	a	a	DET
admet-142	46	9	glass	glass	NOUN
admet-142	46	10	-	-	PUNCT
admet-142	46	11	bottomed	bottom	VERB
admet-142	46	12	dish	dish	NOUN
admet-142	46	13	,	,	PUNCT
admet-142	46	14	and	and	CCONJ
admet-142	46	15	the	the	DET
admet-142	46	16	caco-2	caco-2	NUM
admet-142	46	17	cells	cell	NOUN
admet-142	46	18	were	be	AUX
admet-142	46	19	incubated	incubate	VERB
admet-142	46	20	with	with	ADP
admet-142	46	21	5	5	NUM
admet-142	46	22	µm	µm	ADP
admet-142	46	23	rhodamine	rhodamine	NOUN
admet-142	46	24	123	123	NUM
admet-142	46	25	for	for	ADP
admet-142	46	26	90	90	NUM
admet-142	46	27	min	min	NOUN
admet-142	46	28	at	at	ADP
admet-142	46	29	37	37	NUM
admet-142	46	30	°	°	NOUN
admet-142	46	31	c	c	NOUN
admet-142	46	32	.	.	PUNCT
admet-142	47	1	the	the	DET
admet-142	47	2	cells	cell	NOUN
admet-142	47	3	were	be	AUX
admet-142	47	4	rinsed	rinse	VERB
admet-142	47	5	with	with	ADP
admet-142	47	6	hanks	hanks	PROPN
admet-142	47	7	’	'	PUNCT
admet-142	47	8	balanced	balanced	ADJ
admet-142	47	9	salt	salt	NOUN
admet-142	47	10	solution	solution	NOUN
admet-142	47	11	(	(	PUNCT
admet-142	47	12	hbss	hbss	NOUN
admet-142	47	13	)	)	PUNCT
admet-142	47	14	.	.	PUNCT
admet-142	48	1	hbss	hbss	NOUN
admet-142	48	2	with	with	ADP
admet-142	48	3	or	or	CCONJ
admet-142	48	4	without	without	ADP
admet-142	48	5	mapk	mapk	NOUN
admet-142	48	6	pathway	pathway	NOUN
admet-142	48	7	inhibitors	inhibitor	NOUN
admet-142	48	8	was	be	AUX
admet-142	48	9	added	add	VERB
admet-142	48	10	to	to	ADP
admet-142	48	11	the	the	DET
admet-142	48	12	cells	cell	NOUN
admet-142	48	13	(	(	PUNCT
admet-142	48	14	sb203580	sb203580	PROPN
admet-142	48	15	,	,	PUNCT
admet-142	48	16	10	10	NUM
admet-142	48	17	µm	µm	NUM
admet-142	48	18	;	;	PUNCT
admet-142	48	19	cmpd-1	cmpd-1	NUM
admet-142	48	20	,	,	PUNCT
admet-142	48	21	10	10	NUM
admet-142	48	22	µm	µm	NOUN
admet-142	48	23	;	;	PUNCT
admet-142	48	24	sb239063	sb239063	ADJ
admet-142	48	25	,	,	PUNCT
admet-142	48	26	100	100	NUM
admet-142	48	27	nm	nm	NOUN
admet-142	48	28	;	;	PUNCT
admet-142	48	29	sp600125	sp600125	PROPN
admet-142	48	30	,	,	PUNCT
admet-142	48	31	100	100	NUM
admet-142	48	32	nm	nm	NOUN
admet-142	48	33	;	;	PUNCT
admet-142	48	34	fr180204	fr180204	PROPN
admet-142	48	35	,	,	PUNCT
admet-142	48	36	1	1	NUM
admet-142	48	37	µm	µm	NOUN
admet-142	48	38	)	)	PUNCT
admet-142	48	39	,	,	PUNCT
admet-142	48	40	and	and	CCONJ
admet-142	48	41	cells	cell	NOUN
admet-142	48	42	were	be	AUX
admet-142	48	43	observed	observe	VERB
admet-142	48	44	by	by	ADP
admet-142	48	45	time	time	NOUN
admet-142	48	46	-	-	PUNCT
admet-142	48	47	lapse	lapse	NOUN
admet-142	48	48	confocal	confocal	ADJ
admet-142	48	49	laser	laser	NOUN
admet-142	48	50	scanning	scan	VERB
admet-142	48	51	microscopy	microscopy	NOUN
admet-142	48	52	(	(	PUNCT
admet-142	48	53	fig	fig	NOUN
admet-142	48	54	.	.	PUNCT
admet-142	49	1	2	2	NUM
admet-142	49	2	)	)	PUNCT
admet-142	49	3	.	.	PUNCT
admet-142	50	1	quantification	quantification	NOUN
admet-142	50	2	of	of	ADP
admet-142	50	3	the	the	DET
admet-142	50	4	intracellular	intracellular	ADJ
admet-142	50	5	concentration	concentration	NOUN
admet-142	50	6	of	of	ADP
admet-142	50	7	rhodamine	rhodamine	NOUN
admet-142	50	8	123	123	NUM
admet-142	50	9	in	in	ADP
admet-142	50	10	the	the	DET
admet-142	50	11	wakuda	wakuda	NOUN
admet-142	50	12	et	et	PROPN
admet-142	50	13	al	al	PROPN
admet-142	50	14	.	.	PROPN
admet-142	50	15	admet	admet	PROPN
admet-142	50	16	&	&	CCONJ
admet-142	50	17	dmpk	dmpk	PROPN
admet-142	50	18	3(1	3(1	NUM
admet-142	50	19	)	)	PUNCT
admet-142	50	20	(	(	PUNCT
admet-142	50	21	2015	2015	NUM
admet-142	50	22	)	)	PUNCT
admet-142	50	23	77	77	NUM
admet-142	50	24	-	-	SYM
admet-142	50	25	83	83	NUM
admet-142	50	26	80	80	NUM
admet-142	50	27	caco-2	caco-2	NUM
admet-142	50	28	cells	cell	NOUN
admet-142	50	29	was	be	AUX
admet-142	50	30	performed	perform	VERB
admet-142	50	31	using	use	VERB
admet-142	50	32	fluorescent	fluorescent	ADJ
admet-142	50	33	images	image	NOUN
admet-142	50	34	at	at	ADP
admet-142	50	35	several	several	ADJ
admet-142	50	36	time	time	NOUN
admet-142	50	37	points	point	NOUN
admet-142	50	38	(	(	PUNCT
admet-142	50	39	0	0	NUM
admet-142	50	40	,	,	PUNCT
admet-142	50	41	10	10	NUM
admet-142	50	42	,	,	PUNCT
admet-142	50	43	20	20	NUM
admet-142	50	44	,	,	PUNCT
admet-142	50	45	30	30	NUM
admet-142	50	46	,	,	PUNCT
admet-142	50	47	and	and	CCONJ
admet-142	50	48	60	60	NUM
admet-142	50	49	min	min	NOUN
admet-142	50	50	)	)	PUNCT
admet-142	50	51	by	by	ADP
admet-142	50	52	a	a	DET
admet-142	50	53	chronological	chronological	ADJ
admet-142	50	54	measurement	measurement	NOUN
admet-142	50	55	program	program	NOUN
admet-142	50	56	(	(	PUNCT
admet-142	50	57	ez	ez	NOUN
admet-142	50	58	-	-	NOUN
admet-142	50	59	c1	c1	NOUN
admet-142	50	60	;	;	PUNCT
admet-142	50	61	nikon	nikon	PROPN
admet-142	50	62	,	,	PUNCT
admet-142	50	63	tokyo	tokyo	PROPN
admet-142	50	64	,	,	PUNCT
admet-142	50	65	japan	japan	PROPN
admet-142	50	66	)	)	PUNCT
admet-142	50	67	.	.	PUNCT
admet-142	51	1	the	the	DET
admet-142	51	2	fluorescence	fluorescence	ADJ
admet-142	51	3	intensity	intensity	NOUN
admet-142	51	4	at	at	ADP
admet-142	51	5	0	0	NUM
admet-142	51	6	min	min	NOUN
admet-142	51	7	was	be	AUX
admet-142	51	8	defined	define	VERB
admet-142	51	9	as	as	ADP
admet-142	51	10	100	100	NUM
admet-142	51	11	%	%	NOUN
admet-142	51	12	[	[	X
admet-142	51	13	9,10	9,10	NUM
admet-142	51	14	]	]	X
admet-142	51	15	.	.	PUNCT
admet-142	52	1	statistical	statistical	ADJ
admet-142	52	2	analysis	analysis	NOUN
admet-142	52	3	all	all	DET
admet-142	52	4	values	value	NOUN
admet-142	52	5	represent	represent	VERB
admet-142	52	6	the	the	DET
admet-142	52	7	mean	mean	ADJ
admet-142	52	8	±	±	NOUN
admet-142	52	9	standard	standard	NOUN
admet-142	52	10	error	error	NOUN
admet-142	52	11	.	.	PUNCT
admet-142	53	1	the	the	DET
admet-142	53	2	data	datum	NOUN
admet-142	53	3	were	be	AUX
admet-142	53	4	analysed	analyse	VERB
admet-142	53	5	using	use	VERB
admet-142	53	6	a	a	DET
admet-142	53	7	two	two	NUM
admet-142	53	8	-	-	PUNCT
admet-142	53	9	way	way	NOUN
admet-142	53	10	anova	anova	PROPN
admet-142	53	11	followed	follow	VERB
admet-142	53	12	by	by	ADP
admet-142	53	13	a	a	DET
admet-142	53	14	bonferroni	bonferroni	NOUN
admet-142	53	15	post	post	NOUN
admet-142	53	16	-	-	NOUN
admet-142	53	17	test	test	NOUN
admet-142	53	18	to	to	PART
admet-142	53	19	determine	determine	VERB
admet-142	53	20	significance	significance	NOUN
admet-142	53	21	(	(	PUNCT
admet-142	53	22	p	p	X
admet-142	53	23	<	<	X
admet-142	53	24	0.05	0.05	NUM
admet-142	53	25	)	)	PUNCT
admet-142	53	26	.	.	PUNCT
admet-142	54	1	statistical	statistical	ADJ
admet-142	54	2	analyses	analysis	NOUN
admet-142	54	3	were	be	AUX
admet-142	54	4	performed	perform	VERB
admet-142	54	5	using	use	VERB
admet-142	54	6	the	the	DET
admet-142	54	7	graphpad	graphpad	NOUN
admet-142	54	8	prism	prism	NOUN
admet-142	54	9	4.03	4.03	NUM
admet-142	54	10	software	software	NOUN
admet-142	54	11	(	(	PUNCT
admet-142	54	12	graphpad	graphpad	NOUN
admet-142	54	13	software	software	NOUN
admet-142	54	14	,	,	PUNCT
admet-142	54	15	la	la	PROPN
admet-142	54	16	jolla	jolla	PROPN
admet-142	54	17	,	,	PUNCT
admet-142	54	18	ca	ca	PROPN
admet-142	54	19	,	,	PUNCT
admet-142	54	20	u.s.a	u.s.a	PROPN
admet-142	54	21	.	.	PUNCT
admet-142	54	22	)	)	PUNCT
admet-142	54	23	.	.	PUNCT
admet-142	55	1	results	result	NOUN
admet-142	55	2	and	and	CCONJ
admet-142	55	3	discussion	discussion	VERB
admet-142	55	4	the	the	DET
admet-142	55	5	level	level	NOUN
admet-142	55	6	of	of	ADP
admet-142	55	7	residual	residual	ADJ
admet-142	55	8	rhodamine	rhodamine	NOUN
admet-142	55	9	123	123	NUM
admet-142	55	10	fluorescence	fluorescence	NOUN
admet-142	55	11	in	in	ADP
admet-142	55	12	control	control	NOUN
admet-142	55	13	cells	cell	NOUN
admet-142	55	14	and	and	CCONJ
admet-142	55	15	cells	cell	NOUN
admet-142	55	16	treated	treat	VERB
admet-142	55	17	with	with	ADP
admet-142	55	18	mapk	mapk	NOUN
admet-142	55	19	pathway	pathway	NOUN
admet-142	55	20	inhibitors	inhibitor	NOUN
admet-142	55	21	were	be	AUX
admet-142	55	22	measured	measure	VERB
admet-142	55	23	with	with	ADP
admet-142	55	24	time	time	NOUN
admet-142	55	25	-	-	PUNCT
admet-142	55	26	lapse	lapse	NOUN
admet-142	55	27	confocal	confocal	ADJ
admet-142	55	28	laser	laser	NOUN
admet-142	55	29	scanning	scan	VERB
admet-142	55	30	microscopy	microscopy	NOUN
admet-142	55	31	to	to	PART
admet-142	55	32	assess	assess	VERB
admet-142	55	33	p	p	NOUN
admet-142	55	34	-	-	PUNCT
admet-142	55	35	gp	gp	NOUN
admet-142	55	36	activity	activity	NOUN
admet-142	55	37	.	.	PUNCT
admet-142	56	1	treatment	treatment	NOUN
admet-142	56	2	with	with	ADP
admet-142	56	3	10	10	NUM
admet-142	56	4	μm	μm	ADJ
admet-142	56	5	sb203580	sb203580	NOUN
admet-142	56	6	,	,	PUNCT
admet-142	56	7	a	a	DET
admet-142	56	8	competitive	competitive	ADJ
admet-142	56	9	inhibitor	inhibitor	NOUN
admet-142	56	10	of	of	ADP
admet-142	56	11	the	the	DET
admet-142	56	12	p38α	p38α	PROPN
admet-142	56	13	and	and	CCONJ
admet-142	56	14	β	β	PROPN
admet-142	56	15	atp	atp	NOUN
admet-142	56	16	binding	bind	VERB
admet-142	56	17	pocket	pocket	NOUN
admet-142	56	18	,	,	PUNCT
admet-142	56	19	enhanced	enhance	VERB
admet-142	56	20	the	the	DET
admet-142	56	21	fluorescent	fluorescent	NOUN
admet-142	56	22	decrease	decrease	NOUN
admet-142	56	23	significantly	significantly	ADV
admet-142	56	24	at	at	ADP
admet-142	56	25	20	20	NUM
admet-142	56	26	,	,	PUNCT
admet-142	56	27	30	30	NUM
admet-142	56	28	,	,	PUNCT
admet-142	56	29	and	and	CCONJ
admet-142	56	30	60	60	NUM
admet-142	56	31	min	min	NOUN
admet-142	56	32	(	(	PUNCT
admet-142	56	33	fig	fig	NOUN
admet-142	56	34	.	.	PUNCT
admet-142	56	35	3a	3a	NUM
admet-142	56	36	)	)	PUNCT
admet-142	56	37	.	.	PUNCT
admet-142	57	1	in	in	ADP
admet-142	57	2	contrast	contrast	NOUN
admet-142	57	3	,	,	PUNCT
admet-142	57	4	the	the	DET
admet-142	57	5	decrease	decrease	NOUN
admet-142	57	6	in	in	ADP
admet-142	57	7	fluorescent	fluorescent	ADJ
admet-142	57	8	intensity	intensity	NOUN
admet-142	57	9	was	be	AUX
admet-142	57	10	not	not	PART
admet-142	57	11	affected	affect	VERB
admet-142	57	12	by	by	ADP
admet-142	57	13	treatment	treatment	NOUN
admet-142	57	14	with	with	ADP
admet-142	57	15	the	the	DET
admet-142	57	16	jnk	jnk	PROPN
admet-142	57	17	1	1	NUM
admet-142	57	18	,	,	PUNCT
admet-142	57	19	2	2	NUM
admet-142	57	20	,	,	PUNCT
admet-142	57	21	3	3	NUM
admet-142	57	22	inhibitor	inhibitor	NOUN
admet-142	57	23	,	,	PUNCT
admet-142	57	24	sp600125	sp600125	PROPN
admet-142	57	25	(	(	PUNCT
admet-142	57	26	100	100	NUM
admet-142	57	27	nm	nm	NOUN
admet-142	57	28	)	)	PUNCT
admet-142	57	29	,	,	PUNCT
admet-142	57	30	or	or	CCONJ
admet-142	57	31	the	the	DET
admet-142	57	32	erk1/2	erk1/2	PROPN
admet-142	57	33	inhibitor	inhibitor	NOUN
admet-142	57	34	fr180204	fr180204	NOUN
admet-142	57	35	(	(	PUNCT
admet-142	57	36	1	1	NUM
admet-142	57	37	μm	μm	NUM
admet-142	57	38	)	)	PUNCT
admet-142	57	39	(	(	PUNCT
admet-142	57	40	fig	fig	NOUN
admet-142	57	41	.	.	PUNCT
admet-142	58	1	3b	3b	NUM
admet-142	58	2	,	,	PUNCT
admet-142	58	3	c	c	NOUN
admet-142	58	4	)	)	PUNCT
admet-142	58	5	.	.	PUNCT
admet-142	59	1	further	far	ADV
admet-142	59	2	,	,	PUNCT
admet-142	59	3	the	the	DET
admet-142	59	4	decrease	decrease	NOUN
admet-142	59	5	in	in	ADP
admet-142	59	6	fluorescent	fluorescent	ADJ
admet-142	59	7	intensity	intensity	NOUN
admet-142	59	8	was	be	AUX
admet-142	59	9	not	not	PART
admet-142	59	10	affected	affect	VERB
admet-142	59	11	by	by	ADP
admet-142	59	12	the	the	DET
admet-142	59	13	non	non	ADJ
admet-142	59	14	-	-	ADJ
admet-142	59	15	competitive	competitive	ADJ
admet-142	59	16	p38α	p38α	NOUN
admet-142	59	17	inhibitor	inhibitor	NOUN
admet-142	59	18	cmpd-1	cmpd-1	NUM
admet-142	59	19	(	(	PUNCT
admet-142	59	20	10	10	NUM
admet-142	59	21	μm	μm	NOUN
admet-142	59	22	)	)	PUNCT
admet-142	59	23	(	(	PUNCT
admet-142	59	24	fig	fig	NOUN
admet-142	59	25	.	.	PUNCT
admet-142	60	1	3d	3d	NUM
admet-142	60	2	)	)	PUNCT
admet-142	60	3	or	or	CCONJ
admet-142	60	4	a	a	DET
admet-142	60	5	second	second	ADJ
admet-142	60	6	,	,	PUNCT
admet-142	60	7	more	more	ADV
admet-142	60	8	specific	specific	ADJ
admet-142	60	9	competitive	competitive	ADJ
admet-142	60	10	inhibitor	inhibitor	NOUN
admet-142	60	11	of	of	ADP
admet-142	60	12	the	the	DET
admet-142	60	13	p38α	p38α	PROPN
admet-142	60	14	and	and	CCONJ
admet-142	60	15	β	β	PROPN
admet-142	60	16	atp	atp	NOUN
admet-142	60	17	binding	bind	VERB
admet-142	60	18	pocket	pocket	NOUN
admet-142	60	19	,	,	PUNCT
admet-142	60	20	sb239063	sb239063	ADJ
admet-142	60	21	(	(	PUNCT
admet-142	60	22	100	100	NUM
admet-142	60	23	nm	nm	NOUN
admet-142	60	24	)	)	PUNCT
admet-142	60	25	(	(	PUNCT
admet-142	60	26	fig	fig	NOUN
admet-142	60	27	.	.	PUNCT
admet-142	61	1	3e	3e	NUM
admet-142	61	2	)	)	PUNCT
admet-142	61	3	.	.	PUNCT
admet-142	62	1	we	we	PRON
admet-142	62	2	evaluated	evaluate	VERB
admet-142	62	3	the	the	DET
admet-142	62	4	effects	effect	NOUN
admet-142	62	5	of	of	ADP
admet-142	62	6	mapk	mapk	NOUN
admet-142	62	7	pathway	pathway	NOUN
admet-142	62	8	inhibitors	inhibitor	NOUN
admet-142	62	9	on	on	ADP
admet-142	62	10	the	the	DET
admet-142	62	11	activity	activity	NOUN
admet-142	62	12	of	of	ADP
admet-142	62	13	p	p	NOUN
admet-142	62	14	-	-	PUNCT
admet-142	62	15	gp	gp	NOUN
admet-142	62	16	,	,	PUNCT
admet-142	62	17	using	use	VERB
admet-142	62	18	time	time	NOUN
admet-142	62	19	-	-	PUNCT
admet-142	62	20	lapse	lapse	NOUN
admet-142	62	21	confocal	confocal	ADJ
admet-142	62	22	laser	laser	NOUN
admet-142	62	23	scanning	scan	VERB
admet-142	62	24	microscopy	microscopy	NOUN
admet-142	62	25	.	.	PUNCT
admet-142	63	1	sb203580	sb203580	PROPN
admet-142	63	2	enhanced	enhance	VERB
admet-142	63	3	the	the	DET
admet-142	63	4	fluorescent	fluorescent	NOUN
admet-142	63	5	decrease	decrease	NOUN
admet-142	63	6	significantly	significantly	ADV
admet-142	63	7	after	after	ADP
admet-142	63	8	20	20	NUM
admet-142	63	9	min	min	NOUN
admet-142	63	10	.	.	PUNCT
admet-142	64	1	it	it	PRON
admet-142	64	2	is	be	AUX
admet-142	64	3	hypothesized	hypothesize	VERB
admet-142	64	4	that	that	SCONJ
admet-142	64	5	the	the	DET
admet-142	64	6	enhanced	enhanced	ADJ
admet-142	64	7	effect	effect	NOUN
admet-142	64	8	of	of	ADP
admet-142	64	9	sb203580	sb203580	PROPN
admet-142	64	10	is	be	AUX
admet-142	64	11	due	due	ADJ
admet-142	64	12	to	to	ADP
admet-142	64	13	changes	change	NOUN
admet-142	64	14	in	in	ADP
admet-142	64	15	p	p	NOUN
admet-142	64	16	-	-	PUNCT
admet-142	64	17	gp	gp	NOUN
admet-142	64	18	activation	activation	NOUN
admet-142	64	19	,	,	PUNCT
admet-142	64	20	as	as	SCONJ
admet-142	64	21	changes	change	NOUN
admet-142	64	22	to	to	ADP
admet-142	64	23	the	the	DET
admet-142	64	24	p	p	NOUN
admet-142	64	25	-	-	PUNCT
admet-142	64	26	gp	gp	NOUN
admet-142	64	27	expression	expression	NOUN
admet-142	64	28	level	level	NOUN
admet-142	64	29	would	would	AUX
admet-142	64	30	require	require	VERB
admet-142	64	31	at	at	ADV
admet-142	64	32	least	least	ADJ
admet-142	64	33	24	24	NUM
admet-142	64	34	h	h	NOUN
admet-142	64	35	of	of	ADP
admet-142	64	36	drug	drug	NOUN
admet-142	64	37	treatment	treatment	NOUN
admet-142	64	38	.	.	PUNCT
admet-142	65	1	sb203580	sb203580	PROPN
admet-142	65	2	is	be	AUX
admet-142	65	3	a	a	DET
admet-142	65	4	pyridinyl	pyridinyl	NOUN
admet-142	65	5	imidazole	imidazole	NOUN
admet-142	65	6	that	that	PRON
admet-142	65	7	competitively	competitively	ADV
admet-142	65	8	inhibits	inhibit	VERB
admet-142	65	9	atp	atp	NOUN
admet-142	65	10	binding	bind	VERB
admet-142	65	11	and	and	CCONJ
admet-142	65	12	is	be	AUX
admet-142	65	13	widely	widely	ADV
admet-142	65	14	used	use	VERB
admet-142	65	15	in	in	ADP
admet-142	65	16	studies	study	NOUN
admet-142	65	17	for	for	ADP
admet-142	65	18	elucidating	elucidate	VERB
admet-142	65	19	the	the	DET
admet-142	65	20	roles	role	NOUN
admet-142	65	21	of	of	ADP
admet-142	65	22	p38	p38	NOUN
admet-142	65	23	-	-	PUNCT
admet-142	65	24	mapk	mapk	NOUN
admet-142	66	1	[	[	X
admet-142	66	2	11	11	NUM
admet-142	66	3	]	]	PUNCT
admet-142	66	4	.	.	PUNCT
admet-142	67	1	barancík	barancík	PROPN
admet-142	67	2	et	et	PROPN
admet-142	67	3	al	al	PROPN
admet-142	67	4	.	.	PROPN
admet-142	67	5	reported	report	VERB
admet-142	67	6	that	that	SCONJ
admet-142	67	7	treatment	treatment	NOUN
admet-142	67	8	of	of	ADP
admet-142	67	9	the	the	DET
admet-142	67	10	multidrug	multidrug	NOUN
admet-142	67	11	resistant	resistant	ADJ
admet-142	67	12	mouse	mouse	NOUN
admet-142	67	13	leukaemia	leukaemia	NOUN
admet-142	67	14	cell	cell	NOUN
admet-142	67	15	line	line	NOUN
admet-142	67	16	l1210	l1210	PROPN
admet-142	67	17	/	/	SYM
admet-142	67	18	vcr	vcr	NOUN
admet-142	67	19	with	with	ADP
admet-142	67	20	sb203580	sb203580	PROPN
admet-142	67	21	(	(	PUNCT
admet-142	67	22	30	30	NUM
admet-142	67	23	µm	µm	NOUN
admet-142	67	24	)	)	PUNCT
admet-142	67	25	for	for	ADP
admet-142	67	26	3	3	NUM
admet-142	67	27	days	day	NOUN
admet-142	67	28	inhibited	inhibit	VERB
admet-142	67	29	p	p	NOUN
admet-142	67	30	-	-	PUNCT
admet-142	67	31	gp	gp	NOUN
admet-142	68	1	[	[	X
admet-142	68	2	12	12	NUM
admet-142	68	3	]	]	PUNCT
admet-142	68	4	.	.	PUNCT
admet-142	69	1	in	in	ADP
admet-142	69	2	contrast	contrast	NOUN
admet-142	69	3	,	,	PUNCT
admet-142	69	4	our	our	PRON
admet-142	69	5	results	result	NOUN
admet-142	69	6	suggest	suggest	VERB
admet-142	69	7	that	that	SCONJ
admet-142	69	8	treatment	treatment	NOUN
admet-142	69	9	of	of	ADP
admet-142	69	10	the	the	DET
admet-142	69	11	human	human	ADJ
admet-142	69	12	colon	colon	NOUN
admet-142	69	13	adenocarcinoma	adenocarcinoma	NOUN
admet-142	69	14	cell	cell	NOUN
admet-142	69	15	line	line	NOUN
admet-142	69	16	caco-2	caco-2	NUM
admet-142	69	17	with	with	ADP
admet-142	69	18	sb203580	sb203580	PROPN
admet-142	69	19	(	(	PUNCT
admet-142	69	20	10	10	NUM
admet-142	69	21	µm	µm	NOUN
admet-142	69	22	)	)	PUNCT
admet-142	69	23	for	for	ADP
admet-142	69	24	60	60	NUM
admet-142	69	25	min	min	NOUN
admet-142	69	26	activates	activate	VERB
admet-142	69	27	p	p	X
admet-142	69	28	-	-	PUNCT
admet-142	69	29	gp	gp	NOUN
admet-142	69	30	.	.	PUNCT
admet-142	70	1	the	the	DET
admet-142	70	2	difference	difference	NOUN
admet-142	70	3	in	in	ADP
admet-142	70	4	effect	effect	NOUN
admet-142	70	5	may	may	AUX
admet-142	70	6	be	be	AUX
admet-142	70	7	due	due	ADJ
admet-142	70	8	to	to	ADP
admet-142	70	9	differences	difference	NOUN
admet-142	70	10	in	in	ADP
admet-142	70	11	cell	cell	NOUN
admet-142	70	12	lines	line	NOUN
admet-142	70	13	,	,	PUNCT
admet-142	70	14	sb203580	sb203580	PROPN
admet-142	70	15	concentration	concentration	NOUN
admet-142	70	16	,	,	PUNCT
admet-142	70	17	and	and	CCONJ
admet-142	70	18	duration	duration	NOUN
admet-142	70	19	of	of	ADP
admet-142	70	20	treatment	treatment	NOUN
admet-142	70	21	.	.	PUNCT
admet-142	71	1	furthermore	furthermore	ADV
admet-142	71	2	,	,	PUNCT
admet-142	71	3	the	the	DET
admet-142	71	4	decrease	decrease	NOUN
admet-142	71	5	in	in	ADP
admet-142	71	6	fluorescent	fluorescent	ADJ
admet-142	71	7	intensity	intensity	NOUN
admet-142	71	8	was	be	AUX
admet-142	71	9	not	not	PART
admet-142	71	10	affected	affect	VERB
admet-142	71	11	by	by	ADP
admet-142	71	12	sp600125	sp600125	PROPN
admet-142	71	13	and	and	CCONJ
admet-142	71	14	fr180204	fr180204	PROPN
admet-142	71	15	.	.	PUNCT
admet-142	72	1	sp600125	sp600125	PROPN
admet-142	72	2	is	be	AUX
admet-142	72	3	a	a	DET
admet-142	72	4	jnk	jnk	PROPN
admet-142	72	5	1	1	NUM
admet-142	72	6	,	,	PUNCT
admet-142	72	7	2	2	NUM
admet-142	72	8	,	,	PUNCT
admet-142	72	9	3	3	NUM
admet-142	72	10	inhibitor	inhibitor	NOUN
admet-142	72	11	and	and	CCONJ
admet-142	72	12	fr180204	fr180204	PROPN
admet-142	72	13	is	be	AUX
admet-142	72	14	an	an	DET
admet-142	72	15	erk1/2	erk1/2	PROPN
admet-142	72	16	inhibitor	inhibitor	NOUN
admet-142	72	17	.	.	PUNCT
admet-142	73	1	our	our	PRON
admet-142	73	2	results	result	NOUN
admet-142	73	3	suggest	suggest	VERB
admet-142	73	4	that	that	SCONJ
admet-142	73	5	the	the	DET
admet-142	73	6	jnkmapk	jnkmapk	PROPN
admet-142	73	7	and	and	CCONJ
admet-142	73	8	erk1/2	erk1/2	PROPN
admet-142	73	9	-	-	PUNCT
admet-142	73	10	mapk	mapk	NOUN
admet-142	73	11	pathways	pathway	NOUN
admet-142	73	12	do	do	AUX
admet-142	73	13	not	not	PART
admet-142	73	14	affect	affect	VERB
admet-142	73	15	p	p	NOUN
admet-142	73	16	-	-	PUNCT
admet-142	73	17	gp	gp	NOUN
admet-142	73	18	activity	activity	NOUN
admet-142	73	19	directly	directly	ADV
admet-142	73	20	or	or	CCONJ
admet-142	73	21	over	over	ADP
admet-142	73	22	the	the	DET
admet-142	73	23	time	time	NOUN
admet-142	73	24	course	course	NOUN
admet-142	73	25	studied	study	VERB
admet-142	73	26	.	.	PUNCT
admet-142	74	1	supporting	support	VERB
admet-142	74	2	our	our	PRON
admet-142	74	3	data	datum	NOUN
admet-142	74	4	,	,	PUNCT
admet-142	74	5	kim	kim	PROPN
admet-142	74	6	et	et	PROPN
admet-142	74	7	al	al	PROPN
admet-142	74	8	.	.	PROPN
admet-142	74	9	have	have	AUX
admet-142	74	10	also	also	ADV
admet-142	74	11	reported	report	VERB
admet-142	74	12	that	that	SCONJ
admet-142	74	13	sp600125	sp600125	PROPN
admet-142	74	14	had	have	VERB
admet-142	74	15	no	no	DET
admet-142	74	16	effect	effect	NOUN
admet-142	74	17	on	on	ADP
admet-142	74	18	p	p	NOUN
admet-142	74	19	-	-	PUNCT
admet-142	74	20	gp	gp	NOUN
admet-142	75	1	[	[	X
admet-142	75	2	13	13	NUM
admet-142	75	3	]	]	PUNCT
admet-142	75	4	.	.	PUNCT
admet-142	76	1	the	the	DET
admet-142	76	2	enhancement	enhancement	NOUN
admet-142	76	3	of	of	ADP
admet-142	76	4	p	p	NOUN
admet-142	76	5	-	-	PUNCT
admet-142	76	6	gp	gp	NOUN
admet-142	76	7	activity	activity	NOUN
admet-142	76	8	following	follow	VERB
admet-142	76	9	sb203580	sb203580	ADJ
admet-142	76	10	treatment	treatment	NOUN
admet-142	76	11	suggested	suggest	VERB
admet-142	76	12	that	that	SCONJ
admet-142	76	13	activation	activation	NOUN
admet-142	76	14	of	of	ADP
admet-142	76	15	the	the	DET
admet-142	76	16	p38mapk	p38mapk	NOUN
admet-142	76	17	pathway	pathway	NOUN
admet-142	76	18	might	might	AUX
admet-142	76	19	inhibit	inhibit	VERB
admet-142	76	20	p	p	NOUN
admet-142	76	21	-	-	PUNCT
admet-142	76	22	gp	gp	NOUN
admet-142	76	23	.	.	PUNCT
admet-142	77	1	as	as	SCONJ
admet-142	77	2	mentioned	mention	VERB
admet-142	77	3	earlier	early	ADV
admet-142	77	4	,	,	PUNCT
admet-142	77	5	sb203580	sb203580	PROPN
admet-142	77	6	competitively	competitively	ADV
admet-142	77	7	inhibits	inhibit	VERB
admet-142	77	8	atp	atp	NOUN
admet-142	77	9	binding	bind	VERB
admet-142	77	10	to	to	ADP
admet-142	77	11	p38	p38	VERB
admet-142	77	12	α	α	NOUN
admet-142	77	13	and	and	CCONJ
admet-142	77	14	β	β	NOUN
admet-142	77	15	.	.	PUNCT
admet-142	78	1	further	far	ADV
admet-142	78	2	,	,	PUNCT
admet-142	78	3	p	p	X
admet-142	78	4	-	-	PUNCT
admet-142	78	5	gp	gp	NOUN
admet-142	78	6	is	be	AUX
admet-142	78	7	an	an	DET
admet-142	78	8	atp	atp	NOUN
admet-142	78	9	-	-	PUNCT
admet-142	78	10	dependent	dependent	ADJ
admet-142	78	11	transporter	transporter	NOUN
admet-142	78	12	.	.	PUNCT
admet-142	79	1	thus	thus	ADV
admet-142	79	2	,	,	PUNCT
admet-142	79	3	we	we	PRON
admet-142	79	4	hypothesized	hypothesize	VERB
admet-142	79	5	that	that	SCONJ
admet-142	79	6	inhibition	inhibition	NOUN
admet-142	79	7	of	of	ADP
admet-142	79	8	atp	atp	NOUN
admet-142	79	9	binding	bind	VERB
admet-142	79	10	to	to	ADP
admet-142	79	11	p38α	p38α	PROPN
admet-142	79	12	and	and	CCONJ
admet-142	79	13	β	β	X
admet-142	79	14	by	by	ADP
admet-142	79	15	sb203580	sb203580	PROPN
admet-142	79	16	might	might	AUX
admet-142	79	17	enhance	enhance	VERB
admet-142	79	18	available	available	ADJ
admet-142	79	19	atp	atp	PROPN
admet-142	79	20	levels	level	NOUN
admet-142	79	21	,	,	PUNCT
admet-142	79	22	thereby	thereby	ADV
admet-142	79	23	enhancing	enhance	VERB
admet-142	79	24	the	the	DET
admet-142	79	25	activation	activation	NOUN
admet-142	79	26	of	of	ADP
admet-142	79	27	p	p	NOUN
admet-142	79	28	-	-	PUNCT
admet-142	79	29	gp	gp	NOUN
admet-142	79	30	.	.	PUNCT
admet-142	80	1	to	to	PART
admet-142	80	2	further	far	ADV
admet-142	80	3	assess	assess	VERB
admet-142	80	4	the	the	DET
admet-142	80	5	contribution	contribution	NOUN
admet-142	80	6	of	of	ADP
admet-142	80	7	p38	p38	NOUN
admet-142	80	8	-	-	PUNCT
admet-142	80	9	mapk	mapk	NOUN
admet-142	80	10	pathways	pathway	NOUN
admet-142	80	11	,	,	PUNCT
admet-142	80	12	cells	cell	NOUN
admet-142	80	13	were	be	AUX
admet-142	80	14	treated	treat	VERB
admet-142	80	15	with	with	ADP
admet-142	80	16	either	either	PRON
admet-142	80	17	cmpd-1	cmpd-1	NUM
admet-142	80	18	or	or	CCONJ
admet-142	80	19	sb239063	sb239063	ADJ
admet-142	80	20	.	.	PUNCT
admet-142	81	1	cmpd-1	cmpd-1	PRON
admet-142	81	2	is	be	AUX
admet-142	81	3	a	a	DET
admet-142	81	4	selective	selective	ADJ
admet-142	81	5	,	,	PUNCT
admet-142	81	6	non	non	ADJ
admet-142	81	7	-	-	ADJ
admet-142	81	8	competitive	competitive	ADJ
admet-142	81	9	inhibitor	inhibitor	NOUN
admet-142	81	10	of	of	ADP
admet-142	81	11	p38α	p38α	PROPN
admet-142	81	12	,	,	PUNCT
admet-142	81	13	and	and	CCONJ
admet-142	81	14	sb239063	sb239063	PROPN
admet-142	81	15	is	be	AUX
admet-142	81	16	a	a	DET
admet-142	81	17	competitive	competitive	ADJ
admet-142	81	18	inhibitor	inhibitor	NOUN
admet-142	81	19	of	of	ADP
admet-142	81	20	p38	p38	NOUN
admet-142	81	21	-	-	PUNCT
admet-142	81	22	mapk	mapk	NOUN
admet-142	82	1	[	[	X
admet-142	82	2	14,15	14,15	NUM
admet-142	82	3	]	]	PUNCT
admet-142	82	4	.	.	PUNCT
admet-142	83	1	importantly	importantly	ADV
admet-142	83	2	,	,	PUNCT
admet-142	83	3	sb239063	sb239063	PROPN
admet-142	83	4	is	be	AUX
admet-142	83	5	more	more	ADV
admet-142	83	6	specific	specific	ADJ
admet-142	83	7	than	than	ADP
admet-142	83	8	sb203580	sb203580	NOUN
admet-142	83	9	[	[	X
admet-142	83	10	15	15	NUM
admet-142	83	11	]	]	PUNCT
admet-142	83	12	.	.	PUNCT
admet-142	84	1	interestingly	interestingly	ADV
admet-142	84	2	,	,	PUNCT
admet-142	84	3	both	both	DET
admet-142	84	4	cmpd-1	cmpd-1	NUM
admet-142	84	5	and	and	CCONJ
admet-142	84	6	sb239063	sb239063	PROPN
admet-142	84	7	had	have	VERB
admet-142	84	8	no	no	DET
admet-142	84	9	detectable	detectable	ADJ
admet-142	84	10	effect	effect	NOUN
admet-142	84	11	on	on	ADP
admet-142	84	12	the	the	DET
admet-142	84	13	activity	activity	NOUN
admet-142	84	14	of	of	ADP
admet-142	84	15	p	p	NOUN
admet-142	84	16	-	-	PUNCT
admet-142	84	17	gp	gp	NOUN
admet-142	84	18	.	.	PUNCT
admet-142	85	1	thus	thus	ADV
admet-142	85	2	,	,	PUNCT
admet-142	85	3	our	our	PRON
admet-142	85	4	results	result	NOUN
admet-142	85	5	suggest	suggest	VERB
admet-142	85	6	that	that	SCONJ
admet-142	85	7	admet	admet	PROPN
admet-142	85	8	&	&	CCONJ
admet-142	85	9	dmpk	dmpk	PROPN
admet-142	85	10	3(1	3(1	NUM
admet-142	85	11	)	)	PUNCT
admet-142	85	12	(	(	PUNCT
admet-142	85	13	2015	2015	NUM
admet-142	85	14	)	)	PUNCT
admet-142	85	15	77	77	NUM
admet-142	85	16	-	-	SYM
admet-142	85	17	83	83	NUM
admet-142	85	18	mitogen	mitogen	NOUN
admet-142	85	19	-	-	PUNCT
admet-142	85	20	activated	activate	VERB
admet-142	85	21	protein	protein	NOUN
admet-142	85	22	kinase	kinase	NOUN
admet-142	85	23	pathway	pathway	NOUN
admet-142	85	24	inhibitors	inhibitor	NOUN
admet-142	85	25	doi	doi	VERB
admet-142	85	26	:	:	PUNCT
admet-142	85	27	10.5599	10.5599	NUM
admet-142	85	28	/	/	SYM
admet-142	85	29	admet.3.1.142	admet.3.1.142	PROPN
admet-142	85	30	81	81	NUM
admet-142	85	31	the	the	DET
admet-142	85	32	p38	p38	NOUN
admet-142	85	33	-	-	PUNCT
admet-142	85	34	mapk	mapk	NOUN
admet-142	85	35	pathway	pathway	NOUN
admet-142	85	36	does	do	AUX
admet-142	85	37	not	not	PART
admet-142	85	38	affect	affect	VERB
admet-142	85	39	p	p	NOUN
admet-142	85	40	-	-	PUNCT
admet-142	85	41	gp	gp	NOUN
admet-142	85	42	directly	directly	ADV
admet-142	85	43	after	after	ADP
admet-142	85	44	a	a	DET
admet-142	85	45	short	short	ADJ
admet-142	85	46	duration	duration	NOUN
admet-142	85	47	of	of	ADP
admet-142	85	48	treatment	treatment	NOUN
admet-142	85	49	.	.	PUNCT
admet-142	86	1	however	however	ADV
admet-142	86	2	,	,	PUNCT
admet-142	86	3	sb203580	sb203580	PROPN
admet-142	86	4	increased	increase	VERB
admet-142	86	5	the	the	DET
admet-142	86	6	transfer	transfer	NOUN
admet-142	86	7	of	of	ADP
admet-142	86	8	rhodamine	rhodamine	NOUN
admet-142	86	9	123	123	NUM
admet-142	86	10	across	across	ADP
admet-142	86	11	the	the	DET
admet-142	86	12	cell	cell	NOUN
admet-142	86	13	membrane	membrane	NOUN
admet-142	86	14	after	after	ADP
admet-142	86	15	20	20	NUM
admet-142	86	16	min	min	NOUN
admet-142	86	17	.	.	PROPN
admet-142	86	18	figure	figure	NOUN
admet-142	86	19	3	3	NUM
admet-142	86	20	.	.	PUNCT
admet-142	86	21	influence	influence	NOUN
admet-142	86	22	of	of	ADP
admet-142	86	23	mapk	mapk	NOUN
admet-142	86	24	pathway	pathway	NOUN
admet-142	86	25	inhibitors	inhibitor	NOUN
admet-142	86	26	on	on	ADP
admet-142	86	27	the	the	DET
admet-142	86	28	time	time	NOUN
admet-142	86	29	-	-	PUNCT
admet-142	86	30	dependent	dependent	ADJ
admet-142	86	31	decrease	decrease	NOUN
admet-142	86	32	in	in	ADP
admet-142	86	33	residual	residual	ADJ
admet-142	86	34	rhodamine	rhodamine	NOUN
admet-142	86	35	123	123	NUM
admet-142	86	36	fluorescence	fluorescence	NOUN
admet-142	86	37	in	in	ADP
admet-142	86	38	the	the	DET
admet-142	86	39	apical	apical	ADJ
admet-142	86	40	region	region	NOUN
admet-142	86	41	of	of	ADP
admet-142	86	42	caco-2	caco-2	NUM
admet-142	86	43	cells	cell	NOUN
admet-142	86	44	,	,	PUNCT
admet-142	86	45	measured	measure	VERB
admet-142	86	46	by	by	ADP
admet-142	86	47	time	time	NOUN
admet-142	86	48	-	-	PUNCT
admet-142	86	49	lapse	lapse	NOUN
admet-142	86	50	confocal	confocal	ADJ
admet-142	86	51	laser	laser	NOUN
admet-142	86	52	scanning	scan	VERB
admet-142	86	53	microscopy	microscopy	NOUN
admet-142	86	54	.	.	PUNCT
admet-142	87	1	each	each	DET
admet-142	87	2	chamber	chamber	NOUN
admet-142	87	3	represents	represent	VERB
admet-142	87	4	a	a	DET
admet-142	87	5	p38	p38	NOUN
admet-142	87	6	-	-	PUNCT
admet-142	87	7	mapk	mapk	NOUN
admet-142	87	8	pathway	pathway	NOUN
admet-142	87	9	inhibitor	inhibitor	NOUN
admet-142	87	10	:	:	PUNCT
admet-142	87	11	(	(	PUNCT
admet-142	87	12	a	a	X
admet-142	87	13	)	)	PUNCT
admet-142	87	14	sb203580	sb203580	NOUN
admet-142	87	15	,	,	PUNCT
admet-142	87	16	10	10	NUM
admet-142	87	17	µm	µm	NOUN
admet-142	87	18	:	:	PUNCT
admet-142	87	19	(	(	PUNCT
admet-142	87	20	b	b	X
admet-142	87	21	)	)	PUNCT
admet-142	87	22	sp600125	sp600125	PROPN
admet-142	87	23	,	,	PUNCT
admet-142	87	24	100	100	NUM
admet-142	87	25	nm	nm	NOUN
admet-142	87	26	;	;	PUNCT
admet-142	87	27	(	(	PUNCT
admet-142	87	28	c	c	X
admet-142	87	29	)	)	PUNCT
admet-142	87	30	fr180204	fr180204	NOUN
admet-142	87	31	,	,	PUNCT
admet-142	87	32	1	1	NUM
admet-142	87	33	µm	µm	NOUN
admet-142	87	34	:	:	PUNCT
admet-142	87	35	(	(	PUNCT
admet-142	87	36	d	d	X
admet-142	87	37	)	)	PUNCT
admet-142	87	38	cmpd-1	cmpd-1	NUM
admet-142	87	39	,	,	PUNCT
admet-142	87	40	10	10	NUM
admet-142	87	41	µm	µm	NOUN
admet-142	87	42	:	:	PUNCT
admet-142	87	43	(	(	PUNCT
admet-142	87	44	e	e	NOUN
admet-142	87	45	)	)	PUNCT
admet-142	87	46	sb239063	sb239063	ADJ
admet-142	87	47	,	,	PUNCT
admet-142	87	48	100	100	NUM
admet-142	87	49	nm	nm	NOUN
admet-142	87	50	.	.	PUNCT
admet-142	88	1	each	each	DET
admet-142	88	2	point	point	NOUN
admet-142	88	3	and	and	CCONJ
admet-142	88	4	bar	bar	NOUN
admet-142	88	5	represents	represent	VERB
admet-142	88	6	the	the	DET
admet-142	88	7	mean	mean	ADJ
admet-142	88	8	±	±	NOUN
admet-142	88	9	standard	standard	NOUN
admet-142	88	10	error	error	NOUN
admet-142	88	11	.	.	PUNCT
admet-142	89	1	n	n	NOUN
admet-142	90	1	=	=	SYM
admet-142	90	2	12	12	NUM
admet-142	90	3	-	-	SYM
admet-142	90	4	18	18	NUM
admet-142	90	5	.	.	PUNCT
admet-142	91	1	*	*	PUNCT
admet-142	91	2	,	,	PUNCT
admet-142	91	3	*	*	PUNCT
admet-142	91	4	*	*	PUNCT
admet-142	91	5	*	*	PUNCT
admet-142	91	6	significant	significant	ADJ
admet-142	91	7	difference	difference	NOUN
admet-142	91	8	between	between	ADP
admet-142	91	9	the	the	DET
admet-142	91	10	control	control	NOUN
admet-142	91	11	group	group	NOUN
admet-142	91	12	and	and	CCONJ
admet-142	91	13	sb203580	sb203580	PROPN
admet-142	91	14	group	group	NOUN
admet-142	91	15	(	(	PUNCT
admet-142	91	16	p	p	X
admet-142	91	17	<	<	X
admet-142	91	18	0.05	0.05	NUM
admet-142	91	19	,	,	PUNCT
admet-142	91	20	0.001	0.001	NUM
admet-142	91	21	)	)	PUNCT
admet-142	91	22	.	.	PUNCT
admet-142	92	1	there	there	PRON
admet-142	92	2	are	be	VERB
admet-142	92	3	two	two	NUM
admet-142	92	4	possible	possible	ADJ
admet-142	92	5	reasons	reason	NOUN
admet-142	92	6	for	for	ADP
admet-142	92	7	the	the	DET
admet-142	92	8	enhanced	enhanced	ADJ
admet-142	92	9	rhodamine	rhodamine	NOUN
admet-142	92	10	transport	transport	NOUN
admet-142	92	11	.	.	PUNCT
admet-142	93	1	firstly	firstly	ADV
admet-142	93	2	,	,	PUNCT
admet-142	93	3	the	the	DET
admet-142	93	4	effect	effect	NOUN
admet-142	93	5	of	of	ADP
admet-142	93	6	sb203580	sb203580	PROPN
admet-142	93	7	could	could	AUX
admet-142	93	8	be	be	AUX
admet-142	93	9	mediated	mediate	VERB
admet-142	93	10	through	through	ADP
admet-142	93	11	pathways	pathway	NOUN
admet-142	93	12	other	other	ADJ
admet-142	93	13	than	than	ADP
admet-142	93	14	the	the	DET
admet-142	93	15	p38	p38	NOUN
admet-142	93	16	-	-	PUNCT
admet-142	93	17	mapk	mapk	NOUN
admet-142	93	18	pathway	pathway	NOUN
admet-142	93	19	.	.	PUNCT
admet-142	94	1	the	the	DET
admet-142	94	2	working	work	VERB
admet-142	94	3	concentration	concentration	NOUN
admet-142	94	4	of	of	ADP
admet-142	94	5	sb203580	sb203580	PROPN
admet-142	94	6	reported	report	VERB
admet-142	94	7	in	in	ADP
admet-142	94	8	the	the	DET
admet-142	94	9	literature	literature	NOUN
admet-142	94	10	is	be	AUX
admet-142	94	11	1	1	NUM
admet-142	94	12	-	-	SYM
admet-142	94	13	20	20	NUM
admet-142	94	14	µm	µm	NOUN
admet-142	94	15	.	.	PUNCT
admet-142	95	1	however	however	ADV
admet-142	95	2	,	,	PUNCT
admet-142	95	3	at	at	ADP
admet-142	95	4	high	high	ADJ
admet-142	95	5	concentrations	concentration	NOUN
admet-142	95	6	,	,	PUNCT
admet-142	95	7	sb203580	sb203580	PROPN
admet-142	95	8	can	can	AUX
admet-142	95	9	also	also	ADV
admet-142	95	10	affect	affect	VERB
admet-142	95	11	raf-1	raf-1	NOUN
admet-142	95	12	,	,	PUNCT
admet-142	95	13	phosphoinositide	phosphoinositide	NOUN
admet-142	95	14	-	-	PUNCT
admet-142	95	15	dependent	dependent	ADJ
admet-142	95	16	protein	protein	NOUN
admet-142	95	17	kinase	kinase	NOUN
admet-142	95	18	1	1	NUM
admet-142	95	19	(	(	PUNCT
admet-142	95	20	pdk1	pdk1	PROPN
admet-142	95	21	)	)	PUNCT
admet-142	95	22	,	,	PUNCT
admet-142	95	23	the	the	DET
admet-142	95	24	transforming	transform	VERB
admet-142	95	25	growth	growth	NOUN
admet-142	95	26	factor	factor	NOUN
admet-142	95	27	-	-	PUNCT
admet-142	95	28	beta	beta	NOUN
admet-142	95	29	(	(	PUNCT
admet-142	95	30	tgf	tgf	PROPN
admet-142	95	31	-	-	PUNCT
admet-142	95	32	β	β	NOUN
admet-142	95	33	)	)	PUNCT
admet-142	95	34	receptor	receptor	NOUN
admet-142	95	35	,	,	PUNCT
admet-142	95	36	cyclooxygenase	cyclooxygenase	NOUN
admet-142	95	37	1	1	NUM
admet-142	95	38	(	(	PUNCT
admet-142	95	39	cox-1	cox-1	NUM
admet-142	95	40	)	)	PUNCT
admet-142	95	41	,	,	PUNCT
admet-142	95	42	and	and	CCONJ
admet-142	95	43	cyclooxygenase	cyclooxygenase	NOUN
admet-142	95	44	2	2	NUM
admet-142	95	45	(	(	PUNCT
admet-142	95	46	cox-2	cox-2	NOUN
admet-142	95	47	)	)	PUNCT
admet-142	96	1	[	[	X
admet-142	96	2	16	16	NUM
admet-142	96	3	]	]	PUNCT
admet-142	96	4	.	.	PUNCT
admet-142	97	1	additionally	additionally	ADV
admet-142	97	2	,	,	PUNCT
admet-142	97	3	lali	lali	PROPN
admet-142	97	4	et	et	PROPN
admet-142	97	5	al	al	PROPN
admet-142	97	6	.	.	PROPN
admet-142	97	7	reported	report	VERB
admet-142	97	8	that	that	SCONJ
admet-142	97	9	low	low	ADJ
admet-142	97	10	concentrations	concentration	NOUN
admet-142	97	11	of	of	ADP
admet-142	97	12	sb203580	sb203580	PROPN
admet-142	97	13	can	can	AUX
admet-142	97	14	inhibit	inhibit	VERB
admet-142	97	15	the	the	DET
admet-142	97	16	phosphorylation	phosphorylation	NOUN
admet-142	97	17	and	and	CCONJ
admet-142	97	18	activation	activation	NOUN
admet-142	97	19	of	of	ADP
admet-142	97	20	protein	protein	NOUN
admet-142	97	21	kinase	kinase	PROPN
admet-142	97	22	b	b	PROPN
admet-142	97	23	wakuda	wakuda	PROPN
admet-142	97	24	et	et	PROPN
admet-142	97	25	al	al	PROPN
admet-142	97	26	.	.	PROPN
admet-142	97	27	admet	admet	PROPN
admet-142	97	28	&	&	CCONJ
admet-142	97	29	dmpk	dmpk	PROPN
admet-142	97	30	3(1	3(1	NUM
admet-142	97	31	)	)	PUNCT
admet-142	97	32	(	(	PUNCT
admet-142	97	33	2015	2015	NUM
admet-142	97	34	)	)	PUNCT
admet-142	97	35	77	77	NUM
admet-142	97	36	-	-	SYM
admet-142	97	37	83	83	NUM
admet-142	97	38	82	82	NUM
admet-142	97	39	(	(	PUNCT
admet-142	97	40	pkb	pkb	PROPN
admet-142	97	41	)	)	PUNCT
admet-142	97	42	,	,	PUNCT
admet-142	97	43	also	also	ADV
admet-142	97	44	known	know	VERB
admet-142	97	45	as	as	ADP
admet-142	97	46	akt	akt	PROPN
admet-142	97	47	,	,	PUNCT
admet-142	97	48	by	by	ADP
admet-142	97	49	inhibiting	inhibit	VERB
admet-142	97	50	the	the	DET
admet-142	97	51	pkb	pkb	PROPN
admet-142	97	52	kinase	kinase	PROPN
admet-142	97	53	,	,	PUNCT
admet-142	97	54	pdk1	pdk1	PROPN
admet-142	97	55	(	(	PUNCT
admet-142	97	56	ic50	ic50	PROPN
admet-142	97	57	,	,	PUNCT
admet-142	97	58	3	3	NUM
admet-142	97	59	-	-	SYM
admet-142	97	60	5	5	NUM
admet-142	97	61	µm	µm	NOUN
admet-142	97	62	)	)	PUNCT
admet-142	98	1	[	[	X
admet-142	98	2	17	17	NUM
admet-142	98	3	]	]	PUNCT
admet-142	98	4	.	.	PUNCT
admet-142	99	1	it	it	PRON
admet-142	99	2	is	be	AUX
admet-142	99	3	possible	possible	ADJ
admet-142	99	4	that	that	SCONJ
admet-142	99	5	the	the	DET
admet-142	99	6	activation	activation	NOUN
admet-142	99	7	of	of	ADP
admet-142	99	8	p	p	NOUN
admet-142	99	9	-	-	PUNCT
admet-142	99	10	gp	gp	NOUN
admet-142	99	11	by	by	ADP
admet-142	99	12	sb203580	sb203580	PROPN
admet-142	99	13	may	may	AUX
admet-142	99	14	occur	occur	VERB
admet-142	99	15	via	via	ADP
admet-142	99	16	one	one	NUM
admet-142	99	17	of	of	ADP
admet-142	99	18	these	these	DET
admet-142	99	19	pathways	pathway	NOUN
admet-142	99	20	.	.	PUNCT
admet-142	100	1	alternatively	alternatively	ADV
admet-142	100	2	,	,	PUNCT
admet-142	100	3	sb203580	sb203580	PROPN
admet-142	100	4	could	could	AUX
admet-142	100	5	cause	cause	VERB
admet-142	100	6	a	a	DET
admet-142	100	7	structural	structural	ADJ
admet-142	100	8	change	change	NOUN
admet-142	100	9	in	in	ADP
admet-142	100	10	p	p	NOUN
admet-142	100	11	-	-	PUNCT
admet-142	100	12	gp	gp	NOUN
admet-142	100	13	.	.	PUNCT
admet-142	101	1	p	p	X
admet-142	101	2	-	-	PUNCT
admet-142	101	3	gp	gp	NOUN
admet-142	101	4	is	be	AUX
admet-142	101	5	one	one	NUM
admet-142	101	6	of	of	ADP
admet-142	101	7	the	the	DET
admet-142	101	8	best	well	ADV
admet-142	101	9	-	-	PUNCT
admet-142	101	10	characterized	characterize	VERB
admet-142	101	11	abc	abc	PROPN
admet-142	101	12	transporters	transporter	NOUN
admet-142	101	13	;	;	PUNCT
admet-142	101	14	however	however	ADV
admet-142	101	15	,	,	PUNCT
admet-142	101	16	the	the	DET
admet-142	101	17	mechanism	mechanism	NOUN
admet-142	101	18	of	of	ADP
admet-142	101	19	substrate	substrate	NOUN
admet-142	101	20	transport	transport	NOUN
admet-142	101	21	is	be	AUX
admet-142	101	22	unclear	unclear	ADJ
admet-142	101	23	.	.	PUNCT
admet-142	102	1	in	in	ADP
admet-142	102	2	particular	particular	ADJ
admet-142	102	3	,	,	PUNCT
admet-142	102	4	it	it	PRON
admet-142	102	5	has	have	AUX
admet-142	102	6	been	be	AUX
admet-142	102	7	hypothesized	hypothesize	VERB
admet-142	102	8	that	that	SCONJ
admet-142	102	9	there	there	PRON
admet-142	102	10	are	be	VERB
admet-142	102	11	many	many	ADJ
admet-142	102	12	possible	possible	ADJ
admet-142	102	13	drug	drug	NOUN
admet-142	102	14	-	-	PUNCT
admet-142	102	15	binding	bind	VERB
admet-142	102	16	sites	site	NOUN
admet-142	102	17	on	on	ADP
admet-142	102	18	p	p	NOUN
admet-142	102	19	-	-	PUNCT
admet-142	102	20	gp	gp	NOUN
admet-142	102	21	,	,	PUNCT
admet-142	102	22	including	include	VERB
admet-142	102	23	up	up	ADP
admet-142	102	24	to	to	PART
admet-142	102	25	seven	seven	NUM
admet-142	102	26	putative	putative	ADJ
admet-142	102	27	binding	bind	VERB
admet-142	102	28	sites	site	NOUN
admet-142	102	29	located	locate	VERB
admet-142	102	30	in	in	ADP
admet-142	102	31	the	the	DET
admet-142	102	32	transmembrane	transmembrane	ADJ
admet-142	102	33	domain	domain	NOUN
admet-142	102	34	of	of	ADP
admet-142	102	35	the	the	DET
admet-142	102	36	protein	protein	NOUN
admet-142	102	37	[	[	X
admet-142	102	38	18	18	NUM
admet-142	102	39	-	-	SYM
admet-142	102	40	20	20	NUM
admet-142	102	41	]	]	PUNCT
admet-142	102	42	.	.	PUNCT
admet-142	103	1	it	it	PRON
admet-142	103	2	is	be	AUX
admet-142	103	3	generally	generally	ADV
admet-142	103	4	accepted	accept	VERB
admet-142	103	5	that	that	SCONJ
admet-142	103	6	transmembrane	transmembrane	ADJ
admet-142	103	7	helices	helix	NOUN
admet-142	103	8	5	5	NUM
admet-142	103	9	,	,	PUNCT
admet-142	103	10	6	6	NUM
admet-142	103	11	,	,	PUNCT
admet-142	103	12	11	11	NUM
admet-142	103	13	,	,	PUNCT
admet-142	103	14	and	and	CCONJ
admet-142	103	15	12	12	NUM
admet-142	103	16	are	be	AUX
admet-142	103	17	involved	involve	VERB
admet-142	103	18	in	in	ADP
admet-142	103	19	p	p	NOUN
admet-142	103	20	-	-	PUNCT
admet-142	103	21	gp	gp	NOUN
admet-142	103	22	substrate	substrate	NOUN
admet-142	103	23	binding	bind	VERB
admet-142	103	24	.	.	PUNCT
admet-142	104	1	one	one	NUM
admet-142	104	2	popular	popular	ADJ
admet-142	104	3	model	model	NOUN
admet-142	104	4	published	publish	VERB
admet-142	104	5	by	by	ADP
admet-142	104	6	shapiro	shapiro	PROPN
admet-142	104	7	et	et	PROPN
admet-142	104	8	al	al	PROPN
admet-142	104	9	.	.	PROPN
admet-142	104	10	suggested	suggest	VERB
admet-142	104	11	that	that	SCONJ
admet-142	104	12	two	two	NUM
admet-142	104	13	different	different	ADJ
admet-142	104	14	functional	functional	ADJ
admet-142	104	15	binding	bind	VERB
admet-142	104	16	sites	site	NOUN
admet-142	104	17	,	,	PUNCT
admet-142	104	18	the	the	DET
admet-142	104	19	r	r	NOUN
admet-142	104	20	-	-	PUNCT
admet-142	104	21	site	site	NOUN
admet-142	104	22	and	and	CCONJ
admet-142	104	23	h	h	NOUN
admet-142	104	24	-	-	PUNCT
admet-142	104	25	site	site	NOUN
admet-142	104	26	,	,	PUNCT
admet-142	104	27	interact	interact	VERB
admet-142	104	28	in	in	ADP
admet-142	104	29	a	a	DET
admet-142	104	30	positive	positive	ADJ
admet-142	104	31	cooperative	cooperative	ADJ
admet-142	104	32	manner.18	manner.18	NOUN
admet-142	104	33	rhodamine	rhodamine	NOUN
admet-142	104	34	123	123	NUM
admet-142	104	35	and	and	CCONJ
admet-142	104	36	anthracylines	anthracyline	NOUN
admet-142	104	37	are	be	AUX
admet-142	104	38	substrates	substrate	NOUN
admet-142	104	39	of	of	ADP
admet-142	104	40	the	the	DET
admet-142	104	41	r	r	NOUN
admet-142	104	42	-	-	PUNCT
admet-142	104	43	site	site	NOUN
admet-142	104	44	,	,	PUNCT
admet-142	104	45	whereas	whereas	SCONJ
admet-142	104	46	colchicine	colchicine	PROPN
admet-142	104	47	is	be	AUX
admet-142	104	48	a	a	DET
admet-142	104	49	substrate	substrate	NOUN
admet-142	104	50	of	of	ADP
admet-142	104	51	the	the	DET
admet-142	104	52	h	h	NOUN
admet-142	104	53	-	-	PUNCT
admet-142	104	54	site	site	NOUN
admet-142	104	55	of	of	ADP
admet-142	104	56	p	p	NOUN
admet-142	104	57	-	-	PUNCT
admet-142	104	58	gp	gp	NOUN
admet-142	104	59	.	.	PUNCT
admet-142	105	1	this	this	DET
admet-142	105	2	two	two	NUM
admet-142	105	3	-	-	PUNCT
admet-142	105	4	site	site	NOUN
admet-142	105	5	hypothesis	hypothesis	NOUN
admet-142	105	6	is	be	AUX
admet-142	105	7	the	the	DET
admet-142	105	8	most	most	ADV
admet-142	105	9	convenient	convenient	ADJ
admet-142	105	10	working	working	NOUN
admet-142	105	11	model	model	NOUN
admet-142	105	12	that	that	PRON
admet-142	105	13	explains	explain	VERB
admet-142	105	14	the	the	DET
admet-142	105	15	mutual	mutual	ADJ
admet-142	105	16	stimulation	stimulation	NOUN
admet-142	105	17	of	of	ADP
admet-142	105	18	p	p	NOUN
admet-142	105	19	-	-	PUNCT
admet-142	105	20	gp	gp	NOUN
admet-142	105	21	-	-	PUNCT
admet-142	105	22	mediated	mediate	VERB
admet-142	105	23	transport	transport	NOUN
admet-142	105	24	by	by	ADP
admet-142	105	25	several	several	ADJ
admet-142	105	26	substrates	substrate	NOUN
admet-142	105	27	.	.	PUNCT
admet-142	106	1	additionally	additionally	ADV
admet-142	106	2	,	,	PUNCT
admet-142	106	3	there	there	PRON
admet-142	106	4	is	be	VERB
admet-142	106	5	evidence	evidence	NOUN
admet-142	106	6	of	of	ADP
admet-142	106	7	a	a	DET
admet-142	106	8	third	third	ADJ
admet-142	106	9	allosteric	allosteric	ADJ
admet-142	106	10	binding	bind	VERB
admet-142	106	11	site	site	NOUN
admet-142	106	12	that	that	PRON
admet-142	106	13	serves	serve	VERB
admet-142	106	14	a	a	DET
admet-142	106	15	regulatory	regulatory	ADJ
admet-142	106	16	function	function	NOUN
admet-142	106	17	and	and	CCONJ
admet-142	106	18	may	may	AUX
admet-142	106	19	be	be	AUX
admet-142	106	20	the	the	DET
admet-142	106	21	site	site	NOUN
admet-142	106	22	of	of	ADP
admet-142	106	23	progesterone	progesterone	NOUN
admet-142	106	24	binding	bind	VERB
admet-142	106	25	[	[	X
admet-142	106	26	21	21	NUM
admet-142	106	27	]	]	PUNCT
admet-142	106	28	.	.	PUNCT
admet-142	107	1	sterz	sterz	VERB
admet-142	107	2	et	et	PROPN
admet-142	107	3	al	al	PROPN
admet-142	107	4	.	.	PROPN
admet-142	107	5	reported	report	VERB
admet-142	107	6	that	that	SCONJ
admet-142	107	7	some	some	DET
admet-142	107	8	substances	substance	NOUN
admet-142	107	9	are	be	AUX
admet-142	107	10	activators	activator	NOUN
admet-142	107	11	of	of	ADP
admet-142	107	12	p	p	NOUN
admet-142	107	13	-	-	PUNCT
admet-142	107	14	gp	gp	NOUN
admet-142	108	1	[	[	X
admet-142	108	2	22	22	NUM
admet-142	108	3	]	]	PUNCT
admet-142	108	4	.	.	PUNCT
admet-142	109	1	further	far	ADV
admet-142	109	2	,	,	PUNCT
admet-142	109	3	kerboeuf	kerboeuf	NOUN
admet-142	109	4	et	et	PROPN
admet-142	109	5	al	al	PROPN
admet-142	109	6	.	.	PROPN
admet-142	109	7	reported	report	VERB
admet-142	109	8	that	that	SCONJ
admet-142	109	9	macrocyclic	macrocyclic	NOUN
admet-142	109	10	lactone	lactone	NOUN
admet-142	109	11	anthelmintics	anthelmintic	NOUN
admet-142	109	12	activate	activate	VERB
admet-142	109	13	p	p	NOUN
admet-142	109	14	-	-	NOUN
admet-142	109	15	gp	gp	NOUN
admet-142	109	16	in	in	ADP
admet-142	109	17	nematodes	nematode	NOUN
admet-142	109	18	and	and	CCONJ
admet-142	109	19	suggested	suggest	VERB
admet-142	109	20	that	that	SCONJ
admet-142	109	21	several	several	ADJ
admet-142	109	22	substituents	substituent	NOUN
admet-142	109	23	in	in	ADP
admet-142	109	24	the	the	DET
admet-142	109	25	macrocyclic	macrocyclic	ADJ
admet-142	109	26	lactone	lactone	NOUN
admet-142	109	27	structure	structure	NOUN
admet-142	109	28	are	be	AUX
admet-142	109	29	involved	involve	VERB
admet-142	109	30	in	in	ADP
admet-142	109	31	modulating	modulate	VERB
admet-142	109	32	p	p	NOUN
admet-142	109	33	-	-	PUNCT
admet-142	109	34	gp	gp	NOUN
admet-142	109	35	activation	activation	NOUN
admet-142	109	36	[	[	X
admet-142	109	37	23	23	NUM
admet-142	109	38	]	]	PUNCT
admet-142	109	39	.	.	PUNCT
admet-142	110	1	conclusions	conclusion	NOUN
admet-142	110	2	the	the	DET
admet-142	110	3	mapk	mapk	NOUN
admet-142	110	4	pathway	pathway	NOUN
admet-142	110	5	does	do	AUX
admet-142	110	6	not	not	PART
admet-142	110	7	affect	affect	VERB
admet-142	110	8	short	short	ADJ
admet-142	110	9	-	-	PUNCT
admet-142	110	10	term	term	NOUN
admet-142	110	11	p	p	NOUN
admet-142	110	12	-	-	PUNCT
admet-142	110	13	gp	gp	NOUN
admet-142	110	14	activation	activation	NOUN
admet-142	110	15	.	.	PUNCT
admet-142	111	1	rather	rather	ADV
admet-142	111	2	,	,	PUNCT
admet-142	111	3	activation	activation	NOUN
admet-142	111	4	of	of	ADP
admet-142	111	5	p	p	NOUN
admet-142	111	6	-	-	PUNCT
admet-142	111	7	gp	gp	NOUN
admet-142	111	8	by	by	ADP
admet-142	111	9	sb203580	sb203580	PROPN
admet-142	111	10	is	be	AUX
admet-142	111	11	likely	likely	ADJ
admet-142	111	12	due	due	ADP
admet-142	111	13	to	to	ADP
admet-142	111	14	either	either	DET
admet-142	111	15	pathways	pathway	NOUN
admet-142	111	16	other	other	ADJ
admet-142	111	17	than	than	ADP
admet-142	111	18	the	the	DET
admet-142	111	19	p38	p38	NOUN
admet-142	111	20	-	-	PUNCT
admet-142	111	21	mapk	mapk	NOUN
admet-142	111	22	pathway	pathway	NOUN
admet-142	111	23	or	or	CCONJ
admet-142	111	24	allosteric	allosteric	ADJ
admet-142	111	25	structural	structural	ADJ
admet-142	111	26	changes	change	NOUN
admet-142	111	27	in	in	ADP
admet-142	111	28	p	p	NOUN
admet-142	111	29	-	-	PUNCT
admet-142	111	30	gp	gp	NOUN
admet-142	111	31	.	.	PUNCT
admet-142	112	1	thus	thus	ADV
admet-142	112	2	,	,	PUNCT
admet-142	112	3	further	further	ADJ
admet-142	112	4	studies	study	NOUN
admet-142	112	5	should	should	AUX
admet-142	112	6	be	be	AUX
admet-142	112	7	performed	perform	VERB
admet-142	112	8	to	to	PART
admet-142	112	9	understand	understand	VERB
admet-142	112	10	the	the	DET
admet-142	112	11	mechanism	mechanism	NOUN
admet-142	112	12	underlying	underlie	VERB
admet-142	112	13	sb203580	sb203580	PROPN
admet-142	112	14	-	-	PUNCT
admet-142	112	15	mediated	mediate	VERB
admet-142	112	16	p	p	NOUN
admet-142	112	17	-	-	PUNCT
admet-142	112	18	gp	gp	NOUN
admet-142	112	19	activation	activation	NOUN
admet-142	112	20	.	.	PUNCT
admet-142	113	1	acknowledgements	acknowledgement	NOUN
admet-142	113	2	:	:	PUNCT
admet-142	113	3	the	the	DET
admet-142	113	4	authors	author	NOUN
admet-142	113	5	declare	declare	VERB
admet-142	113	6	that	that	SCONJ
admet-142	113	7	they	they	PRON
admet-142	113	8	have	have	VERB
admet-142	113	9	no	no	DET
admet-142	113	10	conflicts	conflict	NOUN
admet-142	113	11	of	of	ADP
admet-142	113	12	interest	interest	NOUN
admet-142	113	13	to	to	PART
admet-142	113	14	disclose	disclose	VERB
admet-142	113	15	and	and	CCONJ
admet-142	113	16	funding	funding	NOUN
admet-142	113	17	.	.	PUNCT
admet-142	114	1	the	the	DET
admet-142	114	2	authors	author	NOUN
admet-142	114	3	are	be	AUX
admet-142	114	4	grateful	grateful	ADJ
admet-142	114	5	to	to	PART
admet-142	114	6	prof	prof	VERB
admet-142	114	7	.	.	PUNCT
admet-142	115	1	yoshiyuki	yoshiyuki	PROPN
admet-142	115	2	kagawa	kagawa	PROPN
admet-142	115	3	,	,	PUNCT
admet-142	115	4	prof	prof	PROPN
admet-142	115	5	.	.	PUNCT
admet-142	116	1	junko	junko	PROPN
admet-142	116	2	sugatani	sugatani	PROPN
admet-142	116	3	and	and	CCONJ
admet-142	116	4	prof	prof	PROPN
admet-142	116	5	.	.	PUNCT
admet-142	117	1	hiroshi	hiroshi	PROPN
admet-142	117	2	yamada	yamada	PROPN
admet-142	117	3	for	for	ADP
admet-142	117	4	their	their	PRON
admet-142	117	5	suggestions	suggestion	NOUN
admet-142	117	6	.	.	PUNCT
admet-142	118	1	we	we	PRON
admet-142	118	2	also	also	ADV
admet-142	118	3	thank	thank	VERB
admet-142	118	4	our	our	PRON
admet-142	118	5	colleagues	colleague	NOUN
admet-142	118	6	for	for	ADP
admet-142	118	7	their	their	PRON
admet-142	118	8	helpful	helpful	ADJ
admet-142	118	9	advice	advice	NOUN
admet-142	118	10	and	and	CCONJ
admet-142	118	11	support	support	NOUN
admet-142	118	12	.	.	PUNCT
admet-142	119	1	references	reference	NOUN
admet-142	119	2	[	[	X
admet-142	119	3	1	1	NUM
admet-142	119	4	]	]	PUNCT
admet-142	119	5	f.	f.	PROPN
admet-142	119	6	thiebaut	thiebaut	PROPN
admet-142	119	7	,	,	PUNCT
admet-142	119	8	t.	t.	PROPN
admet-142	119	9	tsuruo	tsuruo	PROPN
admet-142	119	10	,	,	PUNCT
admet-142	119	11	h.	h.	PROPN
admet-142	119	12	hamada	hamada	PROPN
admet-142	119	13	,	,	PUNCT
admet-142	119	14	mm	mm	PROPN
admet-142	119	15	.	.	PUNCT
admet-142	119	16	gottesman	gottesman	PROPN
admet-142	119	17	,	,	PUNCT
admet-142	119	18	i.	i.	PROPN
admet-142	119	19	pastan	pastan	PROPN
admet-142	119	20	,	,	PUNCT
admet-142	119	21	mc	mc	PROPN
admet-142	119	22	.	.	PROPN
admet-142	119	23	willingham	willingham	PROPN
admet-142	119	24	,	,	PUNCT
admet-142	119	25	proc	proc	PROPN
admet-142	119	26	.	.	PUNCT
admet-142	120	1	natl	natl	PROPN
admet-142	120	2	.	.	PUNCT
admet-142	121	1	acad	acad	PROPN
admet-142	121	2	.	.	PUNCT
admet-142	122	1	sci	sci	PROPN
admet-142	122	2	.	.	PROPN
admet-142	122	3	usa	usa	PROPN
admet-142	122	4	.	.	PROPN
admet-142	122	5	84	84	NUM
admet-142	122	6	(	(	PUNCT
admet-142	122	7	1987	1987	NUM
admet-142	122	8	)	)	PUNCT
admet-142	122	9	7735	7735	NUM
admet-142	122	10	-	-	SYM
admet-142	122	11	7738	7738	NUM
admet-142	122	12	.	.	PUNCT
admet-142	123	1	[	[	X
admet-142	123	2	2	2	NUM
admet-142	123	3	]	]	PUNCT
admet-142	123	4	vj	vj	PROPN
admet-142	123	5	.	.	PROPN
admet-142	123	6	wacher	wacher	PROPN
admet-142	123	7	,	,	PUNCT
admet-142	123	8	cy	cy	PROPN
admet-142	123	9	.	.	PROPN
admet-142	123	10	wu	wu	PROPN
admet-142	123	11	,	,	PUNCT
admet-142	123	12	lz	lz	PROPN
admet-142	123	13	.	.	PROPN
admet-142	123	14	benet	benet	PROPN
admet-142	123	15	,	,	PUNCT
admet-142	123	16	mol	mol	PROPN
admet-142	123	17	.	.	PROPN
admet-142	123	18	carcinog	carcinog	PROPN
admet-142	123	19	.	.	PUNCT
admet-142	124	1	13	13	NUM
admet-142	124	2	(	(	PUNCT
admet-142	124	3	2000	2000	NUM
admet-142	124	4	)	)	PUNCT
admet-142	124	5	129	129	NUM
admet-142	124	6	-	-	SYM
admet-142	124	7	134	134	NUM
admet-142	124	8	.	.	PUNCT
admet-142	125	1	[	[	X
admet-142	125	2	3	3	X
admet-142	125	3	]	]	PUNCT
admet-142	125	4	m.	m.	NOUN
admet-142	125	5	hitzl	hitzl	PROPN
admet-142	125	6	,	,	PUNCT
admet-142	125	7	s.	s.	PROPN
admet-142	125	8	drescher	drescher	PROPN
admet-142	125	9	,	,	PUNCT
admet-142	125	10	h.	h.	PROPN
admet-142	125	11	van	van	PROPN
admet-142	125	12	der	der	PROPN
admet-142	125	13	kuip	kuip	PROPN
admet-142	125	14	,	,	PUNCT
admet-142	125	15	e.	e.	PROPN
admet-142	125	16	schäffeler	schäffeler	PROPN
admet-142	125	17	,	,	PUNCT
admet-142	125	18	j.	j.	PROPN
admet-142	125	19	fischer	fischer	PROPN
admet-142	125	20	,	,	PUNCT
admet-142	125	21	m.	m.	NOUN
admet-142	125	22	schwab	schwab	PROPN
admet-142	125	23	,	,	PUNCT
admet-142	125	24	m.	m.	PROPN
admet-142	125	25	eichelbaum	eichelbaum	PROPN
admet-142	125	26	,	,	PUNCT
admet-142	125	27	mf	mf	PROPN
admet-142	125	28	.	.	PROPN
admet-142	125	29	fromm	fromm	PROPN
admet-142	125	30	,	,	PUNCT
admet-142	125	31	pharmacogenetics	pharmacogenetic	NOUN
admet-142	125	32	11	11	NUM
admet-142	125	33	(	(	PUNCT
admet-142	125	34	2001	2001	NUM
admet-142	125	35	)	)	PUNCT
admet-142	125	36	293	293	NUM
admet-142	125	37	-	-	SYM
admet-142	125	38	298	298	NUM
admet-142	125	39	.	.	PUNCT
admet-142	126	1	[	[	X
admet-142	126	2	4	4	NUM
admet-142	126	3	]	]	PUNCT
admet-142	126	4	a.	a.	NOUN
admet-142	126	5	cuadrado	cuadrado	PROPN
admet-142	126	6	,	,	PUNCT
admet-142	126	7	ar	ar	NOUN
admet-142	126	8	nebreda	nebreda	PROPN
admet-142	126	9	,	,	PUNCT
admet-142	126	10	biochem	biochem	PROPN
admet-142	126	11	.	.	PUNCT
admet-142	127	1	j.	j.	PROPN
admet-142	127	2	429	429	PROPN
admet-142	127	3	(	(	PUNCT
admet-142	127	4	2010	2010	NUM
admet-142	127	5	)	)	PUNCT
admet-142	127	6	403	403	NUM
admet-142	127	7	-	-	SYM
admet-142	127	8	417	417	NUM
admet-142	127	9	.	.	PUNCT
admet-142	128	1	[	[	X
admet-142	128	2	5	5	NUM
admet-142	128	3	]	]	SYM
admet-142	128	4	ma	ma	PROPN
admet-142	128	5	.	.	PROPN
admet-142	128	6	bogoyevitch	bogoyevitch	PROPN
admet-142	128	7	,	,	PUNCT
admet-142	128	8	kr	kr	PROPN
admet-142	128	9	.	.	PROPN
admet-142	128	10	ngoei	ngoei	PROPN
admet-142	128	11	,	,	PUNCT
admet-142	128	12	tt	tt	PROPN
admet-142	128	13	.	.	PROPN
admet-142	128	14	zhao	zhao	PROPN
admet-142	128	15	,	,	PUNCT
admet-142	128	16	yy	yy	PROPN
admet-142	128	17	.	.	PROPN
admet-142	128	18	yeap	yeap	PROPN
admet-142	128	19	,	,	PUNCT
admet-142	128	20	dc	dc	PROPN
admet-142	128	21	.	.	PUNCT
admet-142	128	22	ng	ng	PROPN
admet-142	128	23	,	,	PUNCT
admet-142	128	24	biochim	biochim	NOUN
admet-142	128	25	.	.	PUNCT
admet-142	129	1	biophys	biophy	NOUN
admet-142	129	2	.	.	PUNCT
admet-142	130	1	acta	acta	PROPN
admet-142	130	2	.	.	PUNCT
admet-142	131	1	1804	1804	NUM
admet-142	131	2	(	(	PUNCT
admet-142	131	3	2010	2010	NUM
admet-142	131	4	)	)	PUNCT
admet-142	131	5	463475	463475	NUM
admet-142	131	6	.	.	PUNCT
admet-142	132	1	[	[	X
admet-142	132	2	6	6	NUM
admet-142	132	3	]	]	PUNCT
admet-142	132	4	s.	s.	PROPN
admet-142	132	5	nishimoto	nishimoto	PROPN
admet-142	132	6	,	,	PUNCT
admet-142	132	7	e.	e.	PROPN
admet-142	132	8	nishida	nishida	PROPN
admet-142	132	9	,	,	PUNCT
admet-142	132	10	embo	embo	PROPN
admet-142	132	11	rep	rep	PROPN
admet-142	132	12	.	.	PROPN
admet-142	132	13	7	7	NUM
admet-142	132	14	(	(	PUNCT
admet-142	132	15	2006	2006	NUM
admet-142	132	16	)	)	PUNCT
admet-142	132	17	782	782	NUM
admet-142	132	18	-	-	SYM
admet-142	132	19	786	786	NUM
admet-142	132	20	.	.	PUNCT
admet-142	133	1	[	[	X
admet-142	133	2	7	7	X
admet-142	133	3	]	]	X
admet-142	133	4	m.	m.	NOUN
admet-142	133	5	fujishiro	fujishiro	PROPN
admet-142	133	6	,	,	PUNCT
admet-142	133	7	y.	y.	PROPN
admet-142	133	8	gotoh	gotoh	PROPN
admet-142	133	9	,	,	PUNCT
admet-142	133	10	h.	h.	PROPN
admet-142	133	11	katagiri	katagiri	PROPN
admet-142	133	12	,	,	PUNCT
admet-142	133	13	h.	h.	PROPN
admet-142	133	14	sakoda	sakoda	PROPN
admet-142	133	15	,	,	PUNCT
admet-142	133	16	t.	t.	PROPN
admet-142	133	17	ogihara	ogihara	PROPN
admet-142	133	18	,	,	PUNCT
admet-142	133	19	m.	m.	NOUN
admet-142	133	20	anai	anai	NOUN
admet-142	133	21	,	,	PUNCT
admet-142	133	22	y.	y.	PROPN
admet-142	133	23	onishi	onishi	PROPN
admet-142	133	24	,	,	PUNCT
admet-142	133	25	h.	h.	PROPN
admet-142	133	26	ono	ono	PROPN
admet-142	133	27	,	,	PUNCT
admet-142	133	28	m.	m.	NOUN
admet-142	133	29	funaki	funaki	PROPN
admet-142	133	30	,	,	PUNCT
admet-142	133	31	k.	k.	PROPN
admet-142	133	32	inukai	inukai	PROPN
admet-142	133	33	,	,	PUNCT
admet-142	133	34	y.	y.	PROPN
admet-142	133	35	fukushima	fukushima	PROPN
admet-142	133	36	,	,	PUNCT
admet-142	133	37	m.	m.	PROPN
admet-142	133	38	kikuchi	kikuchi	PROPN
admet-142	133	39	,	,	PUNCT
admet-142	133	40	y.	y.	PROPN
admet-142	133	41	oka	oka	PROPN
admet-142	133	42	,	,	PUNCT
admet-142	133	43	t.	t.	PROPN
admet-142	133	44	asano	asano	PROPN
admet-142	133	45	,	,	PUNCT
admet-142	133	46	j.	j.	PROPN
admet-142	133	47	biol	biol	PROPN
admet-142	133	48	.	.	PUNCT
admet-142	134	1	chem	chem	NOUN
admet-142	134	2	.	.	PUNCT
admet-142	135	1	276	276	NUM
admet-142	135	2	(	(	PUNCT
admet-142	135	3	2001	2001	NUM
admet-142	135	4	)	)	PUNCT
admet-142	135	5	19800	19800	NUM
admet-142	135	6	-	-	SYM
admet-142	135	7	19806	19806	NUM
admet-142	135	8	.	.	PUNCT
admet-142	136	1	[	[	X
admet-142	136	2	8	8	NUM
admet-142	136	3	]	]	X
admet-142	136	4	mh	mh	PROPN
admet-142	136	5	.	.	PUNCT
admet-142	136	6	nagelin	nagelin	PROPN
admet-142	136	7	,	,	PUNCT
admet-142	136	8	s.	s.	PROPN
admet-142	136	9	srinivasan	srinivasan	PROPN
admet-142	136	10	,	,	PUNCT
admet-142	136	11	jl	jl	PROPN
admet-142	136	12	.	.	PROPN
admet-142	136	13	nadler	nadler	PROPN
admet-142	136	14	,	,	PUNCT
admet-142	136	15	cc	cc	PROPN
admet-142	136	16	.	.	PROPN
admet-142	136	17	hedrick	hedrick	PROPN
admet-142	136	18	,	,	PUNCT
admet-142	136	19	j.	j.	PROPN
admet-142	136	20	biol	biol	PROPN
admet-142	136	21	.	.	PUNCT
admet-142	137	1	chem	chem	NOUN
admet-142	137	2	.	.	PUNCT
admet-142	138	1	284	284	NUM
admet-142	138	2	(	(	PUNCT
admet-142	138	3	2009	2009	NUM
admet-142	138	4	)	)	PUNCT
admet-142	138	5	31303	31303	NUM
admet-142	138	6	-	-	SYM
admet-142	138	7	31314	31314	NUM
admet-142	138	8	.	.	PUNCT
admet-142	139	1	[	[	X
admet-142	139	2	9	9	NUM
admet-142	139	3	]	]	X
admet-142	139	4	h.	h.	PROPN
admet-142	139	5	wakuda	wakuda	PROPN
admet-142	139	6	,	,	PUNCT
admet-142	139	7	n.	n.	PROPN
admet-142	139	8	nejime	nejime	PROPN
admet-142	139	9	,	,	PUNCT
admet-142	139	10	y.	y.	PROPN
admet-142	139	11	tada	tada	PROPN
admet-142	139	12	,	,	PUNCT
admet-142	139	13	s.	s.	PROPN
admet-142	139	14	kagota	kagota	PROPN
admet-142	139	15	,	,	PUNCT
admet-142	139	16	k.	k.	PROPN
admet-142	139	17	umegaki	umegaki	PROPN
admet-142	139	18	,	,	PUNCT
admet-142	139	19	s.	s.	PROPN
admet-142	139	20	yamada	yamada	PROPN
admet-142	139	21	,	,	PUNCT
admet-142	139	22	k.	k.	PROPN
admet-142	139	23	shinozuka	shinozuka	PROPN
admet-142	139	24	,	,	PUNCT
admet-142	139	25	biol	biol	PROPN
admet-142	139	26	.	.	PUNCT
admet-142	140	1	pharma	pharma	PROPN
admet-142	140	2	.	.	PUNCT
admet-142	141	1	bull	bull	NOUN
admet-142	141	2	.	.	PUNCT
admet-142	142	1	33	33	NUM
admet-142	142	2	(	(	PUNCT
admet-142	142	3	2010	2010	NUM
admet-142	142	4	)	)	PUNCT
admet-142	142	5	1238	1238	NUM
admet-142	142	6	-	-	SYM
admet-142	142	7	1241	1241	NUM
admet-142	142	8	.	.	PUNCT
admet-142	143	1	[	[	X
admet-142	143	2	10	10	NUM
admet-142	143	3	]	]	X
admet-142	143	4	h.	h.	PROPN
admet-142	143	5	wakuda	wakuda	PROPN
admet-142	143	6	,	,	PUNCT
admet-142	143	7	n.	n.	PROPN
admet-142	143	8	nejime	nejime	PROPN
admet-142	143	9	,	,	PUNCT
admet-142	143	10	y.	y.	PROPN
admet-142	143	11	tada	tada	PROPN
admet-142	143	12	,	,	PUNCT
admet-142	143	13	s.	s.	PROPN
admet-142	143	14	kagota	kagota	PROPN
admet-142	143	15	,	,	PUNCT
admet-142	143	16	oa	oa	PROPN
admet-142	143	17	.	.	PUNCT
admet-142	143	18	fahmi	fahmi	PROPN
admet-142	143	19	,	,	PUNCT
admet-142	143	20	k.	k.	PROPN
admet-142	143	21	umegaki	umegaki	PROPN
admet-142	143	22	,	,	PUNCT
admet-142	143	23	s.	s.	PROPN
admet-142	143	24	yamada	yamada	PROPN
admet-142	143	25	,	,	PUNCT
admet-142	143	26	k.	k.	PROPN
admet-142	143	27	shinozuka	shinozuka	PROPN
admet-142	143	28	.	.	PUNCT
admet-142	144	1	j.	j.	PROPN
admet-142	144	2	pharm	pharm	PROPN
admet-142	144	3	.	.	PUNCT
admet-142	145	1	pharmacol	pharmacol	PROPN
admet-142	145	2	.	.	PUNCT
admet-142	146	1	63	63	NUM
admet-142	146	2	(	(	PUNCT
admet-142	146	3	2011	2011	NUM
admet-142	146	4	)	)	PUNCT
admet-142	146	5	1015	1015	NUM
admet-142	146	6	-	-	SYM
admet-142	146	7	1021	1021	NUM
admet-142	146	8	.	.	PUNCT
admet-142	147	1	admet	admet	PROPN
admet-142	147	2	&	&	CCONJ
admet-142	147	3	dmpk	dmpk	PROPN
admet-142	147	4	3(1	3(1	NUM
admet-142	147	5	)	)	PUNCT
admet-142	147	6	(	(	PUNCT
admet-142	147	7	2015	2015	NUM
admet-142	147	8	)	)	PUNCT
admet-142	147	9	77	77	NUM
admet-142	147	10	-	-	SYM
admet-142	147	11	83	83	NUM
admet-142	147	12	mitogen	mitogen	NOUN
admet-142	147	13	-	-	PUNCT
admet-142	147	14	activated	activate	VERB
admet-142	147	15	protein	protein	NOUN
admet-142	147	16	kinase	kinase	NOUN
admet-142	147	17	pathway	pathway	NOUN
admet-142	147	18	inhibitors	inhibitor	NOUN
admet-142	147	19	doi	doi	VERB
admet-142	147	20	:	:	PUNCT
admet-142	147	21	10.5599	10.5599	NUM
admet-142	147	22	/	/	SYM
admet-142	147	23	admet.3.1.142	admet.3.1.142	PROPN
admet-142	147	24	83	83	NUM
admet-142	148	1	[	[	X
admet-142	148	2	11	11	NUM
admet-142	148	3	]	]	PUNCT
admet-142	148	4	a.	a.	NOUN
admet-142	148	5	cuenda	cuenda	PROPN
admet-142	148	6	,	,	PUNCT
admet-142	148	7	j.	j.	PROPN
admet-142	148	8	rouse	rouse	PROPN
admet-142	148	9	,	,	PUNCT
admet-142	148	10	yn	yn	PROPN
admet-142	148	11	.	.	PUNCT
admet-142	148	12	doza	doza	PROPN
admet-142	148	13	,	,	PUNCT
admet-142	148	14	r.	r.	PROPN
admet-142	148	15	meier	meier	PROPN
admet-142	148	16	,	,	PUNCT
admet-142	148	17	p.	p.	PROPN
admet-142	148	18	cohen	cohen	PROPN
admet-142	148	19	,	,	PUNCT
admet-142	148	20	tf	tf	PROPN
admet-142	148	21	.	.	PUNCT
admet-142	148	22	gallagher	gallagher	PROPN
admet-142	148	23	,	,	PUNCT
admet-142	148	24	pr	pr	X
admet-142	148	25	.	.	PUNCT
admet-142	149	1	young	young	PROPN
admet-142	149	2	,	,	PUNCT
admet-142	149	3	jc	jc	PROPN
admet-142	149	4	.	.	PROPN
admet-142	149	5	lee	lee	PROPN
admet-142	149	6	,	,	PUNCT
admet-142	149	7	febs	febs	VERB
admet-142	149	8	lett	lett	PROPN
admet-142	149	9	.	.	PUNCT
admet-142	150	1	364	364	NUM
admet-142	150	2	(	(	PUNCT
admet-142	150	3	1995	1995	NUM
admet-142	150	4	)	)	PUNCT
admet-142	150	5	229	229	NUM
admet-142	150	6	-	-	SYM
admet-142	150	7	233	233	NUM
admet-142	150	8	.	.	PUNCT
admet-142	151	1	[	[	X
admet-142	151	2	12	12	NUM
admet-142	151	3	]	]	PUNCT
admet-142	151	4	m.	m.	NOUN
admet-142	151	5	barancík	barancík	PROPN
admet-142	151	6	,	,	PUNCT
admet-142	151	7	v.	v.	PROPN
admet-142	151	8	bohácová	bohácová	PROPN
admet-142	151	9	,	,	PUNCT
admet-142	151	10	j.	j.	PROPN
admet-142	151	11	kvackajová	kvackajová	PROPN
admet-142	151	12	,	,	PUNCT
admet-142	151	13	s.	s.	PROPN
admet-142	151	14	hudecová	hudecová	PROPN
admet-142	151	15	,	,	PUNCT
admet-142	151	16	o.	o.	PROPN
admet-142	151	17	krizanová	krizanová	PROPN
admet-142	151	18	,	,	PUNCT
admet-142	151	19	a.	a.	NOUN
admet-142	151	20	breier	breier	NOUN
admet-142	151	21	,	,	PUNCT
admet-142	151	22	eur	eur	PROPN
admet-142	151	23	.	.	PUNCT
admet-142	151	24	j.	j.	PROPN
admet-142	151	25	pharm	pharm	PROPN
admet-142	151	26	.	.	PUNCT
admet-142	152	1	sci	sci	PROPN
admet-142	152	2	.	.	PROPN
admet-142	153	1	14	14	NUM
admet-142	153	2	(	(	PUNCT
admet-142	153	3	2001	2001	NUM
admet-142	153	4	)	)	PUNCT
admet-142	153	5	29	29	NUM
admet-142	153	6	-	-	SYM
admet-142	153	7	36	36	NUM
admet-142	153	8	.	.	PUNCT
admet-142	154	1	[	[	X
admet-142	154	2	13	13	NUM
admet-142	154	3	]	]	X
admet-142	154	4	jh	jh	PROPN
admet-142	154	5	.	.	PUNCT
admet-142	155	1	kim	kim	PROPN
admet-142	155	2	,	,	PUNCT
admet-142	155	3	m.	m.	NOUN
admet-142	155	4	chae	chae	PROPN
admet-142	155	5	,	,	PUNCT
admet-142	155	6	ar	ar	PROPN
admet-142	155	7	.	.	PROPN
admet-142	155	8	choi	choi	PROPN
admet-142	155	9	,	,	PUNCT
admet-142	155	10	h.	h.	PROPN
admet-142	155	11	sik	sik	PROPN
admet-142	155	12	kim	kim	PROPN
admet-142	155	13	,	,	PUNCT
admet-142	155	14	s.	s.	PROPN
admet-142	155	15	yoon	yoon	PROPN
admet-142	155	16	,	,	PUNCT
admet-142	155	17	eur	eur	PROPN
admet-142	155	18	.	.	PUNCT
admet-142	156	1	j.	j.	PROPN
admet-142	156	2	pharmacol	pharmacol	PROPN
admet-142	156	3	.	.	PROPN
admet-142	157	1	723	723	NUM
admet-142	157	2	(	(	PUNCT
admet-142	157	3	2014	2014	NUM
admet-142	157	4	)	)	PUNCT
admet-142	157	5	141	141	NUM
admet-142	157	6	-	-	SYM
admet-142	157	7	147	147	NUM
admet-142	157	8	.	.	PUNCT
admet-142	158	1	[	[	X
admet-142	158	2	14	14	NUM
admet-142	158	3	]	]	X
admet-142	158	4	w.	w.	PROPN
admet-142	158	5	davidson	davidson	PROPN
admet-142	158	6	,	,	PUNCT
admet-142	158	7	l.	l.	PROPN
admet-142	158	8	frego	frego	PROPN
admet-142	158	9	,	,	PUNCT
admet-142	158	10	gw	gw	PROPN
admet-142	158	11	.	.	PROPN
admet-142	158	12	peet	peet	PROPN
admet-142	158	13	,	,	PUNCT
admet-142	158	14	rr	rr	PROPN
admet-142	158	15	.	.	PUNCT
admet-142	158	16	kroe	kroe	PROPN
admet-142	158	17	,	,	PUNCT
admet-142	158	18	me	me	PROPN
admet-142	158	19	.	.	PUNCT
admet-142	159	1	labadia	labadia	PROPN
admet-142	159	2	,	,	PUNCT
admet-142	159	3	sm	sm	PROPN
admet-142	159	4	.	.	PROPN
admet-142	159	5	lukas	lukas	PROPN
admet-142	159	6	,	,	PUNCT
admet-142	159	7	rj	rj	PROPN
admet-142	159	8	.	.	PROPN
admet-142	159	9	snow	snow	PROPN
admet-142	159	10	,	,	PUNCT
admet-142	159	11	s.	s.	PROPN
admet-142	159	12	jakes	jakes	PROPN
admet-142	159	13	,	,	PUNCT
admet-142	159	14	ca	ca	PROPN
admet-142	159	15	.	.	PUNCT
admet-142	159	16	grygon	grygon	PROPN
admet-142	159	17	,	,	PUNCT
admet-142	159	18	c.	c.	PROPN
admet-142	159	19	pargellis	pargellis	PROPN
admet-142	159	20	,	,	PUNCT
admet-142	159	21	bg	bg	PROPN
admet-142	159	22	.	.	PROPN
admet-142	159	23	werneburg	werneburg	PROPN
admet-142	159	24	,	,	PUNCT
admet-142	159	25	biochemistry	biochemistry	NOUN
admet-142	159	26	43	43	NUM
admet-142	159	27	(	(	PUNCT
admet-142	159	28	2004	2004	NUM
admet-142	159	29	)	)	PUNCT
admet-142	159	30	11658	11658	NUM
admet-142	159	31	-	-	SYM
admet-142	159	32	11671	11671	NUM
admet-142	159	33	.	.	PUNCT
admet-142	160	1	[	[	X
admet-142	160	2	15	15	NUM
admet-142	160	3	]	]	X
admet-142	160	4	dc	dc	PROPN
admet-142	160	5	.	.	PUNCT
admet-142	160	6	underwood	underwood	PROPN
admet-142	160	7	,	,	PUNCT
admet-142	160	8	rr	rr	PROPN
admet-142	160	9	.	.	PROPN
admet-142	160	10	osborn	osborn	PROPN
admet-142	160	11	,	,	PUNCT
admet-142	160	12	cj	cj	PROPN
admet-142	160	13	.	.	PUNCT
admet-142	160	14	kotzer	kotzer	PROPN
admet-142	160	15	,	,	PUNCT
admet-142	160	16	jl	jl	PROPN
admet-142	160	17	.	.	PROPN
admet-142	160	18	adams	adams	PROPN
admet-142	160	19	,	,	PUNCT
admet-142	160	20	jc	jc	PROPN
admet-142	160	21	.	.	PROPN
admet-142	160	22	lee	lee	PROPN
admet-142	160	23	,	,	PUNCT
admet-142	160	24	ef	ef	PROPN
admet-142	160	25	.	.	PROPN
admet-142	160	26	webb	webb	PROPN
admet-142	160	27	,	,	PUNCT
admet-142	160	28	dc	dc	PROPN
admet-142	160	29	.	.	PUNCT
admet-142	160	30	carpenter	carpenter	PROPN
admet-142	160	31	,	,	PUNCT
admet-142	160	32	s.	s.	PROPN
admet-142	160	33	bochnowicz	bochnowicz	PROPN
admet-142	160	34	,	,	PUNCT
admet-142	160	35	hc	hc	PROPN
admet-142	160	36	.	.	PROPN
admet-142	160	37	thomas	thomas	PROPN
admet-142	160	38	,	,	PUNCT
admet-142	160	39	dw	dw	PROPN
admet-142	160	40	.	.	PROPN
admet-142	161	1	hay	hay	PROPN
admet-142	161	2	,	,	PUNCT
admet-142	161	3	de	de	PROPN
admet-142	161	4	.	.	PROPN
admet-142	161	5	griswold	griswold	PROPN
admet-142	161	6	,	,	PUNCT
admet-142	161	7	j.	j.	PROPN
admet-142	161	8	pharmacol	pharmacol	PROPN
admet-142	161	9	.	.	PUNCT
admet-142	162	1	exp	exp	PROPN
admet-142	162	2	.	.	PUNCT
admet-142	163	1	ther	ther	PROPN
admet-142	163	2	.	.	PUNCT
admet-142	164	1	293	293	NUM
admet-142	164	2	(	(	PUNCT
admet-142	164	3	2000	2000	NUM
admet-142	164	4	)	)	PUNCT
admet-142	164	5	281	281	NUM
admet-142	164	6	-	-	SYM
admet-142	164	7	288	288	NUM
admet-142	164	8	.	.	PUNCT
admet-142	165	1	[	[	X
admet-142	165	2	16	16	X
admet-142	165	3	]	]	X
admet-142	165	4	y.	y.	PROPN
admet-142	165	5	zhang	zhang	PROPN
admet-142	165	6	y	y	PROPN
admet-142	165	7	,	,	PUNCT
admet-142	165	8	j.	j.	PROPN
admet-142	165	9	zhou	zhou	PROPN
admet-142	165	10	,	,	PUNCT
admet-142	165	11	w.	w.	PROPN
admet-142	165	12	xu	xu	PROPN
admet-142	165	13	,	,	PUNCT
admet-142	165	14	a.	a.	PROPN
admet-142	165	15	li	li	PROPN
admet-142	165	16	,	,	PUNCT
admet-142	165	17	j.	j.	PROPN
admet-142	165	18	zhou	zhou	PROPN
admet-142	165	19	,	,	PUNCT
admet-142	165	20	s.	s.	PROPN
admet-142	165	21	xu	xu	PROPN
admet-142	165	22	,	,	PUNCT
admet-142	165	23	j.	j.	PROPN
admet-142	165	24	toxicol	toxicol	PROPN
admet-142	165	25	.	.	PUNCT
admet-142	166	1	environ	environ	PROPN
admet-142	166	2	.	.	PUNCT
admet-142	167	1	health	health	NOUN
admet-142	167	2	.	.	PUNCT
admet-142	168	1	a.	a.	NOUN
admet-142	168	2	72	72	NUM
admet-142	168	3	(	(	PUNCT
admet-142	168	4	2009	2009	NUM
admet-142	168	5	)	)	PUNCT
admet-142	168	6	774	774	NUM
admet-142	168	7	-	-	SYM
admet-142	168	8	781	781	NUM
admet-142	168	9	.	.	PUNCT
admet-142	169	1	[	[	X
admet-142	169	2	17	17	NUM
admet-142	169	3	]	]	SYM
admet-142	169	4	fv	fv	PROPN
admet-142	169	5	.	.	PROPN
admet-142	169	6	lali	lali	PROPN
admet-142	169	7	,	,	PUNCT
admet-142	169	8	ae	ae	PROPN
admet-142	169	9	.	.	PUNCT
admet-142	169	10	hunt	hunt	PROPN
admet-142	169	11	,	,	PUNCT
admet-142	169	12	sj	sj	PROPN
admet-142	169	13	.	.	PUNCT
admet-142	169	14	turner	turner	PROPN
admet-142	169	15	,	,	PUNCT
admet-142	169	16	bm	bm	PROPN
admet-142	169	17	.	.	PUNCT
admet-142	170	1	foxwell	foxwell	PROPN
admet-142	170	2	,	,	PUNCT
admet-142	170	3	j.	j.	PROPN
admet-142	170	4	biol	biol	PROPN
admet-142	170	5	.	.	PUNCT
admet-142	171	1	chem	chem	NOUN
admet-142	171	2	.	.	PUNCT
admet-142	172	1	275	275	NUM
admet-142	172	2	(	(	PUNCT
admet-142	172	3	2000	2000	NUM
admet-142	172	4	)	)	PUNCT
admet-142	172	5	7395	7395	NUM
admet-142	172	6	-	-	SYM
admet-142	172	7	7402	7402	NUM
admet-142	172	8	.	.	PUNCT
admet-142	173	1	[	[	X
admet-142	173	2	18	18	NUM
admet-142	173	3	]	]	X
admet-142	173	4	ab	ab	PROPN
admet-142	173	5	.	.	PROPN
admet-142	173	6	shapiro	shapiro	PROPN
admet-142	173	7	,	,	PUNCT
admet-142	173	8	v.	v.	PROPN
admet-142	173	9	ling	ling	PROPN
admet-142	173	10	,	,	PUNCT
admet-142	173	11	biochem	biochem	PROPN
admet-142	173	12	.	.	PUNCT
admet-142	174	1	pharmacol	pharmacol	NOUN
admet-142	174	2	.	.	PUNCT
admet-142	175	1	53	53	NUM
admet-142	175	2	(	(	PUNCT
admet-142	175	3	1997	1997	NUM
admet-142	175	4	)	)	PUNCT
admet-142	175	5	587	587	NUM
admet-142	175	6	-	-	SYM
admet-142	175	7	596	596	NUM
admet-142	175	8	.	.	PUNCT
admet-142	176	1	[	[	X
admet-142	176	2	19	19	NUM
admet-142	176	3	]	]	X
admet-142	176	4	c.	c.	PROPN
admet-142	176	5	martin	martin	PROPN
admet-142	176	6	,	,	PUNCT
admet-142	176	7	g.	g.	PROPN
admet-142	176	8	berridge	berridge	PROPN
admet-142	176	9	,	,	PUNCT
admet-142	176	10	cf	cf	X
admet-142	176	11	.	.	PUNCT
admet-142	177	1	higgins	higgins	PROPN
admet-142	177	2	,	,	PUNCT
admet-142	177	3	p.	p.	PROPN
admet-142	177	4	mistry	mistry	PROPN
admet-142	177	5	,	,	PUNCT
admet-142	177	6	p.	p.	PROPN
admet-142	177	7	charlton	charlton	PROPN
admet-142	177	8	,	,	PUNCT
admet-142	177	9	r.	r.	PROPN
admet-142	177	10	callaghan	callaghan	PROPN
admet-142	177	11	,	,	PUNCT
admet-142	177	12	mol	mol	PROPN
admet-142	177	13	.	.	PROPN
admet-142	177	14	pharmacol	pharmacol	PROPN
admet-142	177	15	.	.	PUNCT
admet-142	178	1	58	58	NUM
admet-142	178	2	(	(	PUNCT
admet-142	178	3	2000	2000	NUM
admet-142	178	4	)	)	PUNCT
admet-142	178	5	624	624	NUM
admet-142	178	6	-	-	SYM
admet-142	178	7	632	632	NUM
admet-142	178	8	.	.	PUNCT
admet-142	179	1	[	[	X
admet-142	179	2	20	20	NUM
admet-142	179	3	]	]	SYM
admet-142	179	4	ar	ar	PROPN
admet-142	179	5	.	.	PROPN
admet-142	179	6	safa	safa	PROPN
admet-142	179	7	,	,	PUNCT
admet-142	179	8	curr	curr	PROPN
admet-142	179	9	.	.	PROPN
admet-142	179	10	med	med	PROPN
admet-142	179	11	.	.	PROPN
admet-142	179	12	chem	chem	PROPN
admet-142	179	13	.	.	PUNCT
admet-142	180	1	anticancer	anticancer	NOUN
admet-142	180	2	agents	agent	NOUN
admet-142	180	3	.	.	PUNCT
admet-142	181	1	4	4	NUM
admet-142	181	2	(	(	PUNCT
admet-142	181	3	2004	2004	NUM
admet-142	181	4	)	)	PUNCT
admet-142	181	5	1	1	NUM
admet-142	181	6	-	-	SYM
admet-142	181	7	17	17	NUM
admet-142	181	8	.	.	PUNCT
admet-142	182	1	[	[	X
admet-142	182	2	21	21	NUM
admet-142	182	3	]	]	X
admet-142	182	4	ab	ab	PROPN
admet-142	182	5	.	.	PROPN
admet-142	182	6	shapiro	shapiro	PROPN
admet-142	182	7	,	,	PUNCT
admet-142	182	8	k.	k.	PROPN
admet-142	182	9	fox	fox	PROPN
admet-142	182	10	,	,	PUNCT
admet-142	182	11	p.	p.	PROPN
admet-142	182	12	lam	lam	PROPN
admet-142	182	13	,	,	PUNCT
admet-142	182	14	v.	v.	PROPN
admet-142	182	15	ling	ling	PROPN
admet-142	182	16	,	,	PUNCT
admet-142	182	17	eur	eur	PROPN
admet-142	182	18	.	.	PUNCT
admet-142	183	1	j.	j.	PROPN
admet-142	183	2	biochem	biochem	PROPN
admet-142	183	3	.	.	PUNCT
admet-142	184	1	259	259	NUM
admet-142	184	2	(	(	PUNCT
admet-142	184	3	1999	1999	NUM
admet-142	184	4	)	)	PUNCT
admet-142	184	5	841	841	NUM
admet-142	184	6	-	-	SYM
admet-142	184	7	850	850	NUM
admet-142	184	8	.	.	PUNCT
admet-142	185	1	[	[	X
admet-142	185	2	22	22	NUM
admet-142	185	3	]	]	PUNCT
admet-142	185	4	k.	k.	PROPN
admet-142	185	5	sterz	sterz	PROPN
admet-142	185	6	,	,	PUNCT
admet-142	185	7	l.	l.	PROPN
admet-142	185	8	möllmann	möllmann	PROPN
admet-142	185	9	,	,	PUNCT
admet-142	185	10	a.	a.	PROPN
admet-142	185	11	jacobs	jacobs	PROPN
admet-142	185	12	,	,	PUNCT
admet-142	185	13	d.	d.	PROPN
admet-142	185	14	baumert	baumert	PROPN
admet-142	185	15	,	,	PUNCT
admet-142	185	16	m.	m.	PROPN
admet-142	185	17	wiese	wiese	PROPN
admet-142	185	18	,	,	PUNCT
admet-142	185	19	chemmedchem	chemmedchem	PROPN
admet-142	185	20	4	4	NUM
admet-142	185	21	(	(	PUNCT
admet-142	185	22	2009	2009	NUM
admet-142	185	23	)	)	PUNCT
admet-142	185	24	1897	1897	NUM
admet-142	185	25	-	-	SYM
admet-142	185	26	1911	1911	NUM
admet-142	185	27	.	.	PUNCT
admet-142	186	1	[	[	X
admet-142	186	2	23	23	NUM
admet-142	186	3	]	]	X
admet-142	186	4	d.	d.	PROPN
admet-142	186	5	kerboeuf	kerboeuf	PROPN
admet-142	186	6	,	,	PUNCT
admet-142	186	7	f.	f.	PROPN
admet-142	186	8	guégnard	guégnard	PROPN
admet-142	186	9	,	,	PUNCT
admet-142	186	10	antimicrob	antimicrob	PROPN
admet-142	186	11	.	.	PUNCT
admet-142	187	1	agents	agents	PROPN
admet-142	187	2	chemother	chemother	PROPN
admet-142	187	3	.	.	PUNCT
admet-142	188	1	55	55	NUM
admet-142	188	2	(	(	PUNCT
admet-142	188	3	2011	2011	NUM
admet-142	188	4	)	)	PUNCT
admet-142	188	5	2224	2224	NUM
admet-142	188	6	-	-	SYM
admet-142	188	7	2232	2232	NUM
admet-142	188	8	.	.	PUNCT
admet-142	189	1	©	©	PROPN
admet-142	189	2	2015	2015	NUM
admet-142	189	3	by	by	ADP
admet-142	189	4	the	the	DET
admet-142	189	5	authors	author	NOUN
admet-142	189	6	;	;	PUNCT
admet-142	189	7	licensee	licensee	PROPN
admet-142	189	8	iapc	iapc	PROPN
admet-142	189	9	,	,	PUNCT
admet-142	189	10	zagreb	zagreb	PROPN
admet-142	189	11	,	,	PUNCT
admet-142	189	12	croatia	croatia	PROPN
admet-142	189	13	.	.	PUNCT
admet-142	190	1	this	this	DET
admet-142	190	2	article	article	NOUN
admet-142	190	3	is	be	AUX
admet-142	190	4	an	an	DET
admet-142	190	5	open	open	ADJ
admet-142	190	6	-	-	PUNCT
admet-142	190	7	access	access	NOUN
admet-142	190	8	article	article	NOUN
admet-142	190	9	distributed	distribute	VERB
admet-142	190	10	under	under	ADP
admet-142	190	11	the	the	DET
admet-142	190	12	terms	term	NOUN
admet-142	190	13	and	and	CCONJ
admet-142	190	14	conditions	condition	NOUN
admet-142	190	15	of	of	ADP
admet-142	190	16	the	the	DET
admet-142	190	17	creative	creative	ADJ
admet-142	190	18	commons	common	NOUN
admet-142	190	19	attribution	attribution	NOUN
admet-142	190	20	license	license	NOUN
admet-142	190	21	(	(	PUNCT
admet-142	190	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-142	190	23	)	)	PUNCT
admet-142	190	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN