id	sid	tid	token	lemma	pos
admet-1437	1	1	numerical	numerical	ADJ
admet-1437	1	2	modeling	modeling	NOUN
admet-1437	1	3	of	of	ADP
admet-1437	1	4	the	the	DET
admet-1437	1	5	dissolution	dissolution	NOUN
admet-1437	1	6	of	of	ADP
admet-1437	1	7	drug	drug	NOUN
admet-1437	1	8	nanocrystals	nanocrystal	NOUN
admet-1437	1	9	and	and	CCONJ
admet-1437	1	10	its	its	PRON
admet-1437	1	11	application	application	NOUN
admet-1437	1	12	to	to	ADP
admet-1437	1	13	industrial	industrial	ADJ
admet-1437	1	14	product	product	NOUN
admet-1437	1	15	development	development	NOUN
admet-1437	1	16	doi	doi	PROPN
admet-1437	1	17	:	:	PUNCT
admet-1437	1	18	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	1	19	253	253	NUM
admet-1437	1	20	admet	admet	X
admet-1437	1	21	&	&	CCONJ
admet-1437	1	22	dmpk	dmpk	PROPN
admet-1437	1	23	10(4	10(4	NUM
admet-1437	1	24	)	)	PUNCT
admet-1437	1	25	(	(	PUNCT
admet-1437	1	26	2022	2022	NUM
admet-1437	1	27	)	)	PUNCT
admet-1437	1	28	253	253	NUM
admet-1437	1	29	-	-	SYM
admet-1437	1	30	287	287	NUM
admet-1437	1	31	;	;	PUNCT
admet-1437	1	32	doi	doi	NOUN
admet-1437	1	33	:	:	PUNCT
admet-1437	1	34	https://doi.org/10.5599/admet.1437	https://doi.org/10.5599/admet.1437	NOUN
admet-1437	1	35	open	open	ADJ
admet-1437	1	36	access	access	NOUN
admet-1437	1	37	:	:	PUNCT
admet-1437	1	38	issn	issn	PROPN
admet-1437	1	39	:	:	PUNCT
admet-1437	1	40	1848	1848	NUM
admet-1437	1	41	-	-	SYM
admet-1437	1	42	7718	7718	NUM
admet-1437	1	43	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-1437	1	44	original	original	ADJ
admet-1437	1	45	scientific	scientific	ADJ
admet-1437	1	46	paper	paper	NOUN
admet-1437	1	47	numerical	numerical	ADJ
admet-1437	1	48	modeling	modeling	NOUN
admet-1437	1	49	of	of	ADP
admet-1437	1	50	the	the	DET
admet-1437	1	51	dissolution	dissolution	NOUN
admet-1437	1	52	of	of	ADP
admet-1437	1	53	drug	drug	NOUN
admet-1437	1	54	nanocrystals	nanocrystal	NOUN
admet-1437	1	55	and	and	CCONJ
admet-1437	1	56	its	its	PRON
admet-1437	1	57	application	application	NOUN
admet-1437	1	58	to	to	ADP
admet-1437	1	59	industrial	industrial	ADJ
admet-1437	1	60	product	product	NOUN
admet-1437	1	61	development1	development1	NOUN
admet-1437	1	62	bastian	bastian	PROPN
admet-1437	1	63	bonhoeffer	bonhoeffer	PROPN
admet-1437	1	64	,	,	PUNCT
admet-1437	1	65	andreas	andreas	PROPN
admet-1437	1	66	kordikowski	kordikowski	PROPN
admet-1437	1	67	,	,	PUNCT
admet-1437	1	68	edgar	edgar	PROPN
admet-1437	1	69	john	john	PROPN
admet-1437	1	70	and	and	CCONJ
admet-1437	1	71	michael	michael	PROPN
admet-1437	1	72	juhnke	juhnke	PROPN
admet-1437	1	73	*	*	PUNCT
admet-1437	1	74	novartis	novartis	PROPN
admet-1437	1	75	pharma	pharma	PROPN
admet-1437	1	76	ag	ag	PROPN
admet-1437	1	77	,	,	PUNCT
admet-1437	1	78	technical	technical	ADJ
admet-1437	1	79	r&d	r&d	PROPN
admet-1437	1	80	,	,	PUNCT
admet-1437	1	81	forum	forum	NOUN
admet-1437	1	82	1	1	NUM
admet-1437	1	83	,	,	PUNCT
admet-1437	1	84	novartis	novartis	NOUN
admet-1437	1	85	campus	campus	NOUN
admet-1437	1	86	,	,	PUNCT
admet-1437	1	87	4056	4056	NUM
admet-1437	1	88	basel	basel	PROPN
admet-1437	1	89	,	,	PUNCT
admet-1437	1	90	switzerland	switzerland	PROPN
admet-1437	1	91	*	*	PUNCT
admet-1437	1	92	corresponding	correspond	VERB
admet-1437	1	93	author	author	NOUN
admet-1437	1	94	:	:	PUNCT
admet-1437	1	95	e	e	NOUN
admet-1437	1	96	-	-	NOUN
admet-1437	1	97	mail	mail	NOUN
admet-1437	1	98	:	:	PUNCT
admet-1437	1	99	michael.juhnke@gmx.ch	michael.juhnke@gmx.ch	VERB
admet-1437	1	100	received	receive	VERB
admet-1437	1	101	:	:	PUNCT
admet-1437	1	102	june	june	PROPN
admet-1437	1	103	30	30	NUM
admet-1437	1	104	,	,	PUNCT
admet-1437	1	105	2022	2022	NUM
admet-1437	1	106	;	;	PUNCT
admet-1437	1	107	revised	revise	VERB
admet-1437	1	108	:	:	PUNCT
admet-1437	1	109	august	august	PROPN
admet-1437	1	110	02	02	NUM
admet-1437	1	111	,	,	PUNCT
admet-1437	1	112	2022	2022	NUM
admet-1437	1	113	;	;	PUNCT
admet-1437	1	114	published	publish	VERB
admet-1437	1	115	:	:	PUNCT
admet-1437	1	116	august	august	PROPN
admet-1437	1	117	04	04	NUM
admet-1437	1	118	,	,	PUNCT
admet-1437	1	119	2022	2022	NUM
admet-1437	1	120	abstract	abstract	NOUN
admet-1437	1	121	the	the	DET
admet-1437	1	122	apparent	apparent	ADJ
admet-1437	1	123	solubility	solubility	NOUN
admet-1437	1	124	of	of	ADP
admet-1437	1	125	drug	drug	NOUN
admet-1437	1	126	nanocrystals	nanocrystal	NOUN
admet-1437	1	127	in	in	ADP
admet-1437	1	128	equilibrium	equilibrium	NOUN
admet-1437	1	129	was	be	AUX
admet-1437	1	130	experimentally	experimentally	ADV
admet-1437	1	131	determined	determine	VERB
admet-1437	1	132	for	for	ADP
admet-1437	1	133	a	a	DET
admet-1437	1	134	drugstabilizer	drugstabilizer	NOUN
admet-1437	1	135	system	system	NOUN
admet-1437	1	136	with	with	ADP
admet-1437	1	137	different	different	ADJ
admet-1437	1	138	particle	particle	NOUN
admet-1437	1	139	size	size	NOUN
admet-1437	1	140	distributions	distribution	NOUN
admet-1437	1	141	.	.	PUNCT
admet-1437	2	1	true	true	ADJ
admet-1437	2	2	supersaturation	supersaturation	NOUN
admet-1437	2	3	was	be	AUX
admet-1437	2	4	identified	identify	VERB
admet-1437	2	5	for	for	ADP
admet-1437	2	6	ultrafine	ultrafine	ADJ
admet-1437	2	7	drug	drug	NOUN
admet-1437	2	8	nanocrystals	nanocrystal	NOUN
admet-1437	2	9	with	with	ADP
admet-1437	2	10	an	an	DET
admet-1437	2	11	almost	almost	ADV
admet-1437	2	12	2	2	NUM
admet-1437	2	13	-	-	ADJ
admet-1437	2	14	fold	fold	ADJ
admet-1437	2	15	increase	increase	NOUN
admet-1437	2	16	compared	compare	VERB
admet-1437	2	17	to	to	ADP
admet-1437	2	18	the	the	DET
admet-1437	2	19	thermodynamic	thermodynamic	ADJ
admet-1437	2	20	solubility	solubility	NOUN
admet-1437	2	21	of	of	ADP
admet-1437	2	22	related	related	ADJ
admet-1437	2	23	coarse	coarse	ADJ
admet-1437	2	24	drug	drug	NOUN
admet-1437	2	25	crystals	crystal	NOUN
admet-1437	2	26	,	,	PUNCT
admet-1437	2	27	highlighting	highlight	VERB
admet-1437	2	28	their	their	PRON
admet-1437	2	29	enabling	enable	VERB
admet-1437	2	30	potential	potential	NOUN
admet-1437	2	31	to	to	PART
admet-1437	2	32	enhance	enhance	VERB
admet-1437	2	33	bioavailability	bioavailability	NOUN
admet-1437	2	34	.	.	PUNCT
admet-1437	3	1	the	the	DET
admet-1437	3	2	experimental	experimental	ADJ
admet-1437	3	3	results	result	NOUN
admet-1437	3	4	were	be	AUX
admet-1437	3	5	applied	apply	VERB
admet-1437	3	6	to	to	PART
admet-1437	3	7	investigate	investigate	VERB
admet-1437	3	8	in	in	ADP
admet-1437	3	9	silico	silico	NOUN
admet-1437	3	10	the	the	DET
admet-1437	3	11	associated	associated	ADJ
admet-1437	3	12	dissolution	dissolution	NOUN
admet-1437	3	13	behavior	behavior	NOUN
admet-1437	3	14	in	in	ADP
admet-1437	3	15	a	a	DET
admet-1437	3	16	closed	closed	ADJ
admet-1437	3	17	system	system	NOUN
admet-1437	3	18	by	by	ADP
admet-1437	3	19	numerical	numerical	ADJ
admet-1437	3	20	modeling	modeling	NOUN
admet-1437	3	21	according	accord	VERB
admet-1437	3	22	to	to	ADP
admet-1437	3	23	the	the	DET
admet-1437	3	24	ostwald	ostwald	NOUN
admet-1437	3	25	-	-	PUNCT
admet-1437	3	26	freundlich	freundlich	NOUN
admet-1437	3	27	and	and	CCONJ
admet-1437	3	28	noyes	noyes	PROPN
admet-1437	3	29	-	-	PUNCT
admet-1437	3	30	whitney	whitney	PROPN
admet-1437	3	31	/	/	SYM
admet-1437	3	32	nernst	nernst	PROPN
admet-1437	3	33	-	-	PUNCT
admet-1437	3	34	brunner	brunner	PROPN
admet-1437	3	35	equations	equation	NOUN
admet-1437	3	36	.	.	PUNCT
admet-1437	4	1	calculated	calculate	VERB
admet-1437	4	2	results	result	NOUN
admet-1437	4	3	were	be	AUX
admet-1437	4	4	found	find	VERB
admet-1437	4	5	to	to	PART
admet-1437	4	6	be	be	AUX
admet-1437	4	7	in	in	ADP
admet-1437	4	8	agreement	agreement	NOUN
admet-1437	4	9	with	with	ADP
admet-1437	4	10	the	the	DET
admet-1437	4	11	experimental	experimental	ADJ
admet-1437	4	12	results	result	NOUN
admet-1437	4	13	only	only	ADV
admet-1437	4	14	when	when	SCONJ
admet-1437	4	15	the	the	DET
admet-1437	4	16	entire	entire	ADJ
admet-1437	4	17	particle	particle	NOUN
admet-1437	4	18	size	size	NOUN
admet-1437	4	19	distribution	distribution	NOUN
admet-1437	4	20	of	of	ADP
admet-1437	4	21	drug	drug	NOUN
admet-1437	4	22	nanocrystals	nanocrystal	NOUN
admet-1437	4	23	was	be	AUX
admet-1437	4	24	considered	consider	VERB
admet-1437	4	25	.	.	PUNCT
admet-1437	5	1	in	in	ADP
admet-1437	5	2	silico	silico	NOUN
admet-1437	5	3	dissolution	dissolution	NOUN
admet-1437	5	4	,	,	PUNCT
admet-1437	5	5	studies	study	NOUN
admet-1437	5	6	were	be	AUX
admet-1437	5	7	conducted	conduct	VERB
admet-1437	5	8	to	to	PART
admet-1437	5	9	simulate	simulate	VERB
admet-1437	5	10	the	the	DET
admet-1437	5	11	complex	complex	ADJ
admet-1437	5	12	interplay	interplay	NOUN
admet-1437	5	13	between	between	ADP
admet-1437	5	14	drug	drug	NOUN
admet-1437	5	15	nanocrystals	nanocrystal	NOUN
admet-1437	5	16	,	,	PUNCT
admet-1437	5	17	dissolution	dissolution	NOUN
admet-1437	5	18	conditions	condition	NOUN
admet-1437	5	19	and	and	CCONJ
admet-1437	5	20	resulting	result	VERB
admet-1437	5	21	temporal	temporal	ADJ
admet-1437	5	22	progression	progression	NOUN
admet-1437	5	23	during	during	ADP
admet-1437	5	24	dissolution	dissolution	NOUN
admet-1437	5	25	up	up	ADP
admet-1437	5	26	to	to	ADP
admet-1437	5	27	the	the	DET
admet-1437	5	28	equilibrium	equilibrium	NOUN
admet-1437	5	29	state	state	NOUN
admet-1437	5	30	.	.	PUNCT
admet-1437	6	1	calculations	calculation	NOUN
admet-1437	6	2	were	be	AUX
admet-1437	6	3	performed	perform	VERB
admet-1437	6	4	for	for	ADP
admet-1437	6	5	selected	select	VERB
admet-1437	6	6	in	in	ADP
admet-1437	6	7	vivo	vivo	NOUN
admet-1437	6	8	and	and	CCONJ
admet-1437	6	9	in	in	ADP
admet-1437	6	10	vitro	vitro	X
admet-1437	6	11	scenarios	scenario	NOUN
admet-1437	6	12	considering	consider	VERB
admet-1437	6	13	different	different	ADJ
admet-1437	6	14	drug	drug	NOUN
admet-1437	6	15	nanocrystal	nanocrystal	ADJ
admet-1437	6	16	particle	particle	NOUN
admet-1437	6	17	size	size	NOUN
admet-1437	6	18	distributions	distribution	NOUN
admet-1437	6	19	,	,	PUNCT
admet-1437	6	20	drug	drug	NOUN
admet-1437	6	21	amount	amount	NOUN
admet-1437	6	22	,	,	PUNCT
admet-1437	6	23	dissolution	dissolution	ADJ
admet-1437	6	24	media	medium	NOUN
admet-1437	6	25	and	and	CCONJ
admet-1437	6	26	volume	volume	NOUN
admet-1437	6	27	.	.	PUNCT
admet-1437	7	1	the	the	DET
admet-1437	7	2	achieved	achieve	VERB
admet-1437	7	3	results	result	NOUN
admet-1437	7	4	demonstrated	demonstrate	VERB
admet-1437	7	5	the	the	DET
admet-1437	7	6	importance	importance	NOUN
admet-1437	7	7	of	of	ADP
admet-1437	7	8	ultrafine	ultrafine	ADJ
admet-1437	7	9	drug	drug	NOUN
admet-1437	7	10	nanocrystals	nanocrystal	NOUN
admet-1437	7	11	for	for	ADP
admet-1437	7	12	potential	potential	ADJ
admet-1437	7	13	bioavailability	bioavailability	NOUN
admet-1437	7	14	improvement	improvement	NOUN
admet-1437	7	15	and	and	CCONJ
admet-1437	7	16	the	the	DET
admet-1437	7	17	functional	functional	ADJ
admet-1437	7	18	applicability	applicability	NOUN
admet-1437	7	19	of	of	ADP
admet-1437	7	20	the	the	DET
admet-1437	7	21	modeling	modeling	NOUN
admet-1437	7	22	approach	approach	NOUN
admet-1437	7	23	to	to	PART
admet-1437	7	24	investigate	investigate	VERB
admet-1437	7	25	their	their	PRON
admet-1437	7	26	dissolution	dissolution	ADJ
admet-1437	7	27	behavior	behavior	NOUN
admet-1437	7	28	for	for	ADP
admet-1437	7	29	configurable	configurable	ADJ
admet-1437	7	30	formulation	formulation	NOUN
admet-1437	7	31	variables	variable	NOUN
admet-1437	7	32	in	in	ADP
admet-1437	7	33	product	product	NOUN
admet-1437	7	34	development	development	NOUN
admet-1437	7	35	in	in	ADP
admet-1437	7	36	terms	term	NOUN
admet-1437	7	37	of	of	ADP
admet-1437	7	38	in	in	ADP
admet-1437	7	39	vivo	vivo	NOUN
admet-1437	7	40	and	and	CCONJ
admet-1437	7	41	in	in	ADP
admet-1437	7	42	vitro	vitro	X
admet-1437	7	43	relevant	relevant	ADJ
admet-1437	7	44	conditions	condition	NOUN
admet-1437	7	45	.	.	PUNCT
admet-1437	8	1	©	©	X
admet-1437	8	2	2022	2022	NUM
admet-1437	8	3	by	by	ADP
admet-1437	8	4	the	the	DET
admet-1437	8	5	authors	author	NOUN
admet-1437	8	6	.	.	PUNCT
admet-1437	9	1	this	this	DET
admet-1437	9	2	article	article	NOUN
admet-1437	9	3	is	be	AUX
admet-1437	9	4	an	an	DET
admet-1437	9	5	open	open	ADJ
admet-1437	9	6	-	-	PUNCT
admet-1437	9	7	access	access	NOUN
admet-1437	9	8	article	article	NOUN
admet-1437	9	9	distributed	distribute	VERB
admet-1437	9	10	under	under	ADP
admet-1437	9	11	the	the	DET
admet-1437	9	12	terms	term	NOUN
admet-1437	9	13	and	and	CCONJ
admet-1437	9	14	conditions	condition	NOUN
admet-1437	9	15	of	of	ADP
admet-1437	9	16	the	the	DET
admet-1437	9	17	creative	creative	ADJ
admet-1437	9	18	commons	common	NOUN
admet-1437	9	19	attribution	attribution	NOUN
admet-1437	9	20	license	license	NOUN
admet-1437	9	21	(	(	PUNCT
admet-1437	9	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-1437	9	23	)	)	PUNCT
admet-1437	9	24	.	.	PUNCT
admet-1437	10	1	keywords	keyword	VERB
admet-1437	10	2	bioavailability	bioavailability	NOUN
admet-1437	10	3	;	;	PUNCT
admet-1437	10	4	drug	drug	NOUN
admet-1437	10	5	particles	particle	NOUN
admet-1437	10	6	;	;	PUNCT
admet-1437	10	7	enabling	enable	VERB
admet-1437	10	8	formulation	formulation	NOUN
admet-1437	10	9	;	;	PUNCT
admet-1437	10	10	nanosuspension	nanosuspension	NOUN
admet-1437	10	11	;	;	PUNCT
admet-1437	10	12	supersaturation	supersaturation	NOUN
admet-1437	10	13	;	;	PUNCT
admet-1437	10	14	wet	wet	ADJ
admet-1437	10	15	media	medium	NOUN
admet-1437	10	16	milling	milling	NOUN
admet-1437	10	17	.	.	PUNCT
admet-1437	11	1	introduction	introduction	NOUN
admet-1437	11	2	in	in	ADP
admet-1437	11	3	the	the	DET
admet-1437	11	4	last	last	ADJ
admet-1437	11	5	three	three	NUM
admet-1437	11	6	decades	decade	NOUN
admet-1437	11	7	,	,	PUNCT
admet-1437	11	8	nanocrystals	nanocrystal	NOUN
admet-1437	11	9	have	have	AUX
admet-1437	11	10	emerged	emerge	VERB
admet-1437	11	11	as	as	ADP
admet-1437	11	12	a	a	DET
admet-1437	11	13	formulation	formulation	NOUN
admet-1437	11	14	strategy	strategy	NOUN
admet-1437	11	15	to	to	PART
admet-1437	11	16	improve	improve	VERB
admet-1437	11	17	bioavailabilityrelated	bioavailabilityrelated	ADJ
admet-1437	11	18	problems	problem	NOUN
admet-1437	11	19	of	of	ADP
admet-1437	11	20	poorly	poorly	ADV
admet-1437	11	21	-	-	PUNCT
admet-1437	11	22	soluble	soluble	ADJ
admet-1437	11	23	drugs	drug	NOUN
admet-1437	11	24	,	,	PUNCT
admet-1437	11	25	enhance	enhance	VERB
admet-1437	11	26	clinical	clinical	ADJ
admet-1437	11	27	convenience	convenience	NOUN
admet-1437	11	28	,	,	PUNCT
admet-1437	11	29	and	and	CCONJ
admet-1437	11	30	enable	enable	VERB
admet-1437	11	31	specific	specific	ADJ
admet-1437	11	32	therapeutic	therapeutic	ADJ
admet-1437	11	33	benefits	benefit	NOUN
admet-1437	11	34	[	[	X
admet-1437	11	35	1	1	NUM
admet-1437	11	36	-	-	SYM
admet-1437	11	37	7	7	NUM
admet-1437	11	38	]	]	PUNCT
admet-1437	11	39	.	.	PUNCT
admet-1437	12	1	until	until	ADP
admet-1437	12	2	now	now	ADV
admet-1437	12	3	,	,	PUNCT
admet-1437	12	4	several	several	ADJ
admet-1437	12	5	commercialized	commercialize	VERB
admet-1437	12	6	nanocrystalline	nanocrystalline	ADJ
admet-1437	12	7	drug	drug	NOUN
admet-1437	12	8	products	product	NOUN
admet-1437	12	9	reached	reach	VERB
admet-1437	12	10	the	the	DET
admet-1437	12	11	market	market	NOUN
admet-1437	12	12	for	for	ADP
admet-1437	12	13	oral	oral	ADJ
admet-1437	12	14	,	,	PUNCT
admet-1437	12	15	ocular	ocular	ADJ
admet-1437	12	16	and	and	CCONJ
admet-1437	12	17	injection	injection	NOUN
admet-1437	12	18	(	(	PUNCT
admet-1437	12	19	sc	sc	PROPN
admet-1437	12	20	,	,	PUNCT
admet-1437	12	21	i	i	PRON
admet-1437	12	22	m	m	PROPN
admet-1437	12	23	,	,	PUNCT
admet-1437	12	24	iv	iv	X
admet-1437	12	25	)	)	PUNCT
admet-1437	12	26	routes	route	NOUN
admet-1437	12	27	of	of	ADP
admet-1437	12	28	administration	administration	NOUN
admet-1437	12	29	[	[	X
admet-1437	12	30	8	8	NUM
admet-1437	12	31	-	-	SYM
admet-1437	12	32	10	10	NUM
admet-1437	12	33	]	]	PUNCT
admet-1437	12	34	.	.	PUNCT
admet-1437	13	1	beyond	beyond	ADP
admet-1437	13	2	that	that	PRON
admet-1437	13	3	,	,	PUNCT
admet-1437	13	4	a	a	DET
admet-1437	13	5	small	small	ADJ
admet-1437	13	6	number	number	NOUN
admet-1437	13	7	of	of	ADP
admet-1437	13	8	nanocrystalline	nanocrystalline	ADJ
admet-1437	13	9	drug	drug	NOUN
admet-1437	13	10	products	product	NOUN
admet-1437	13	11	are	be	AUX
admet-1437	13	12	continuously	continuously	ADV
admet-1437	13	13	approaching	approach	VERB
admet-1437	13	14	early	early	ADJ
admet-1437	13	15	development	development	NOUN
admet-1437	13	16	and	and	CCONJ
admet-1437	13	17	the	the	DET
admet-1437	13	18	generic	generic	ADJ
admet-1437	13	19	product	product	NOUN
admet-1437	13	20	lifecycle	lifecycle	NOUN
admet-1437	13	21	[	[	X
admet-1437	13	22	9	9	NUM
admet-1437	13	23	]	]	PUNCT
admet-1437	13	24	.	.	PUNCT
admet-1437	14	1	for	for	ADP
admet-1437	14	2	oral	oral	ADJ
admet-1437	14	3	products	product	NOUN
admet-1437	14	4	,	,	PUNCT
admet-1437	14	5	the	the	DET
admet-1437	14	6	improvement	improvement	NOUN
admet-1437	14	7	of	of	ADP
admet-1437	14	8	the	the	DET
admet-1437	14	9	drug	drug	NOUN
admet-1437	14	10	dissolution	dissolution	NOUN
admet-1437	14	11	rate	rate	NOUN
admet-1437	14	12	through	through	ADP
admet-1437	14	13	an	an	DET
admet-1437	14	14	increase	increase	NOUN
admet-1437	14	15	of	of	ADP
admet-1437	14	16	the	the	DET
admet-1437	14	17	drug	drug	NOUN
admet-1437	14	18	nanocrystal	nanocrystal	PROPN
admet-1437	14	19	specific	specific	ADJ
admet-1437	14	20	surface	surface	NOUN
admet-1437	14	21	area	area	NOUN
admet-1437	14	22	,	,	PUNCT
admet-1437	14	23	the	the	DET
admet-1437	14	24	increase	increase	NOUN
admet-1437	14	25	of	of	ADP
admet-1437	14	26	the	the	DET
admet-1437	14	27	solubility	solubility	NOUN
admet-1437	14	28	due	due	ADP
admet-1437	14	29	to	to	ADP
admet-1437	14	30	ultrafine	ultrafine	NOUN
admet-1437	14	31	nanocrystals	nanocrystal	NOUN
admet-1437	14	32	and	and	CCONJ
admet-1437	14	33	the	the	DET
admet-1437	14	34	adhesion	adhesion	NOUN
admet-1437	14	35	1	1	NUM
admet-1437	14	36	this	this	DET
admet-1437	14	37	paper	paper	NOUN
admet-1437	14	38	is	be	AUX
admet-1437	14	39	dedicated	dedicate	VERB
admet-1437	14	40	to	to	ADP
admet-1437	14	41	the	the	DET
admet-1437	14	42	memory	memory	NOUN
admet-1437	14	43	of	of	ADP
admet-1437	14	44	dr	dr	PROPN
admet-1437	14	45	.	.	PROPN
admet-1437	14	46	konstantin	konstantin	PROPN
admet-1437	14	47	tsinman	tsinman	PROPN
admet-1437	14	48	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	14	49	https://doi.org/10.5599/admet.1437	https://doi.org/10.5599/admet.1437	NUM
admet-1437	14	50	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-1437	14	51	mailto:michael.juhnke@gmx.ch	mailto:michael.juhnke@gmx.ch	NOUN
admet-1437	15	1	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-1437	15	2	bonhoeffer	bonhoeffer	PROPN
admet-1437	15	3	et	et	PROPN
admet-1437	15	4	al	al	PROPN
admet-1437	15	5	.	.	PROPN
admet-1437	15	6	admet	admet	PROPN
admet-1437	15	7	&	&	CCONJ
admet-1437	15	8	dmpk	dmpk	PROPN
admet-1437	15	9	10(4	10(4	NUM
admet-1437	15	10	)	)	PUNCT
admet-1437	15	11	(	(	PUNCT
admet-1437	15	12	2022	2022	NUM
admet-1437	15	13	)	)	PUNCT
admet-1437	15	14	253	253	NUM
admet-1437	15	15	-	-	SYM
admet-1437	15	16	287	287	NUM
admet-1437	15	17	254	254	NUM
admet-1437	15	18	of	of	ADP
admet-1437	15	19	nanocrystals	nanocrystal	NOUN
admet-1437	15	20	to	to	ADP
admet-1437	15	21	the	the	DET
admet-1437	15	22	gut	gut	NOUN
admet-1437	15	23	wall	wall	NOUN
admet-1437	15	24	are	be	AUX
admet-1437	15	25	considered	consider	VERB
admet-1437	15	26	the	the	DET
admet-1437	15	27	main	main	ADJ
admet-1437	15	28	contributing	contribute	VERB
admet-1437	15	29	factors	factor	NOUN
admet-1437	15	30	to	to	ADP
admet-1437	15	31	bioavailability	bioavailability	NOUN
admet-1437	15	32	improvement	improvement	NOUN
admet-1437	15	33	[	[	X
admet-1437	15	34	8,11	8,11	NOUN
admet-1437	15	35	]	]	PUNCT
admet-1437	15	36	.	.	PUNCT
admet-1437	16	1	on	on	ADP
admet-1437	16	2	the	the	DET
admet-1437	16	3	other	other	ADJ
admet-1437	16	4	hand	hand	NOUN
admet-1437	16	5	,	,	PUNCT
admet-1437	16	6	ocular	ocular	ADJ
admet-1437	16	7	and	and	CCONJ
admet-1437	16	8	injectable	injectable	ADJ
admet-1437	16	9	products	product	NOUN
admet-1437	16	10	are	be	AUX
admet-1437	16	11	most	most	ADV
admet-1437	16	12	often	often	ADV
admet-1437	16	13	associated	associate	VERB
admet-1437	16	14	with	with	ADP
admet-1437	16	15	improved	improved	ADJ
admet-1437	16	16	clinical	clinical	ADJ
admet-1437	16	17	convenience	convenience	NOUN
admet-1437	16	18	,	,	PUNCT
admet-1437	16	19	like	like	ADP
admet-1437	16	20	the	the	DET
admet-1437	16	21	ease	ease	NOUN
admet-1437	16	22	of	of	ADP
admet-1437	16	23	administration	administration	NOUN
admet-1437	16	24	and	and	CCONJ
admet-1437	16	25	reduced	reduce	VERB
admet-1437	16	26	dosing	dose	VERB
admet-1437	16	27	frequency	frequency	NOUN
admet-1437	16	28	or	or	CCONJ
admet-1437	16	29	specific	specific	ADJ
admet-1437	16	30	therapeutic	therapeutic	ADJ
admet-1437	16	31	benefits	benefit	NOUN
admet-1437	16	32	like	like	ADP
admet-1437	16	33	continuous	continuous	ADJ
admet-1437	16	34	and	and	CCONJ
admet-1437	16	35	controlled	control	VERB
admet-1437	16	36	release	release	NOUN
admet-1437	16	37	[	[	X
admet-1437	16	38	12	12	NUM
admet-1437	16	39	-	-	SYM
admet-1437	16	40	14	14	NUM
admet-1437	16	41	]	]	PUNCT
admet-1437	16	42	.	.	PUNCT
admet-1437	17	1	the	the	DET
admet-1437	17	2	manufacturing	manufacturing	NOUN
admet-1437	17	3	of	of	ADP
admet-1437	17	4	drug	drug	NOUN
admet-1437	17	5	nanocrystals	nanocrystal	NOUN
admet-1437	17	6	for	for	ADP
admet-1437	17	7	industrial	industrial	ADJ
admet-1437	17	8	applications	application	NOUN
admet-1437	17	9	is	be	AUX
admet-1437	17	10	most	most	ADV
admet-1437	17	11	often	often	ADV
admet-1437	17	12	performed	perform	VERB
admet-1437	17	13	by	by	ADP
admet-1437	17	14	wet	wet	ADJ
admet-1437	17	15	media	medium	NOUN
admet-1437	17	16	milling	milling	NOUN
admet-1437	17	17	technology	technology	NOUN
admet-1437	17	18	[	[	X
admet-1437	17	19	15	15	NUM
admet-1437	17	20	-	-	SYM
admet-1437	17	21	19	19	NUM
admet-1437	17	22	]	]	PUNCT
admet-1437	17	23	.	.	PUNCT
admet-1437	18	1	in	in	ADP
admet-1437	18	2	essence	essence	NOUN
admet-1437	18	3	,	,	PUNCT
admet-1437	18	4	size	size	NOUN
admet-1437	18	5	reduction	reduction	NOUN
admet-1437	18	6	of	of	ADP
admet-1437	18	7	drug	drug	NOUN
admet-1437	18	8	particles	particle	NOUN
admet-1437	18	9	takes	take	VERB
admet-1437	18	10	place	place	NOUN
admet-1437	18	11	in	in	ADP
admet-1437	18	12	aqueous	aqueous	ADJ
admet-1437	18	13	suspension	suspension	NOUN
admet-1437	18	14	in	in	ADP
admet-1437	18	15	the	the	DET
admet-1437	18	16	presence	presence	NOUN
admet-1437	18	17	of	of	ADP
admet-1437	18	18	stabilizers	stabilizer	NOUN
admet-1437	18	19	between	between	ADP
admet-1437	18	20	colliding	collide	VERB
admet-1437	18	21	grinding	grind	VERB
admet-1437	18	22	media	medium	NOUN
admet-1437	18	23	.	.	PUNCT
admet-1437	19	1	the	the	DET
admet-1437	19	2	technology	technology	NOUN
admet-1437	19	3	is	be	AUX
admet-1437	19	4	in	in	ADP
admet-1437	19	5	a	a	DET
admet-1437	19	6	mature	mature	ADJ
admet-1437	19	7	state	state	NOUN
admet-1437	19	8	and	and	CCONJ
admet-1437	19	9	considered	consider	VERB
admet-1437	19	10	a	a	DET
admet-1437	19	11	versatile	versatile	ADJ
admet-1437	19	12	drug	drug	NOUN
admet-1437	19	13	delivery	delivery	NOUN
admet-1437	19	14	platform	platform	NOUN
admet-1437	19	15	owing	owe	VERB
admet-1437	19	16	to	to	ADP
admet-1437	19	17	its	its	PRON
admet-1437	19	18	industrial	industrial	ADJ
admet-1437	19	19	applicability	applicability	NOUN
admet-1437	19	20	for	for	ADP
admet-1437	19	21	oral	oral	ADJ
admet-1437	19	22	,	,	PUNCT
admet-1437	19	23	ocular	ocular	ADJ
admet-1437	19	24	,	,	PUNCT
admet-1437	19	25	and	and	CCONJ
admet-1437	19	26	injectable	injectable	ADJ
admet-1437	19	27	products	product	NOUN
admet-1437	19	28	from	from	ADP
admet-1437	19	29	the	the	DET
admet-1437	19	30	pre	pre	NOUN
admet-1437	19	31	-	-	ADJ
admet-1437	19	32	clinical	clinical	ADJ
admet-1437	19	33	up	up	ADP
admet-1437	19	34	to	to	ADP
admet-1437	19	35	the	the	DET
admet-1437	19	36	commercial	commercial	ADJ
admet-1437	19	37	stage	stage	NOUN
admet-1437	19	38	.	.	PUNCT
admet-1437	20	1	wet	wet	ADJ
admet-1437	20	2	media	medium	NOUN
admet-1437	20	3	milled	mill	VERB
admet-1437	20	4	drug	drug	NOUN
admet-1437	20	5	nanocrystals	nanocrystal	NOUN
admet-1437	20	6	are	be	AUX
admet-1437	20	7	mostly	mostly	ADV
admet-1437	20	8	reported	report	VERB
admet-1437	20	9	with	with	ADP
admet-1437	20	10	product	product	NOUN
admet-1437	20	11	particle	particle	NOUN
admet-1437	20	12	sizes	size	NOUN
admet-1437	20	13	between	between	ADP
admet-1437	20	14	about	about	ADV
admet-1437	20	15	150	150	NUM
admet-1437	20	16	to	to	PART
admet-1437	20	17	300	300	NUM
admet-1437	20	18	nm	nm	NOUN
admet-1437	20	19	.	.	PUNCT
admet-1437	21	1	interestingly	interestingly	ADV
admet-1437	21	2	,	,	PUNCT
admet-1437	21	3	only	only	ADV
admet-1437	21	4	a	a	DET
admet-1437	21	5	few	few	ADJ
admet-1437	21	6	reports	report	NOUN
admet-1437	21	7	are	be	AUX
admet-1437	21	8	available	available	ADJ
admet-1437	21	9	on	on	ADP
admet-1437	21	10	the	the	DET
admet-1437	21	11	manufacturing	manufacturing	NOUN
admet-1437	21	12	of	of	ADP
admet-1437	21	13	sub-100	sub-100	ADJ
admet-1437	21	14	nm	nm	ADJ
admet-1437	21	15	drug	drug	NOUN
admet-1437	21	16	nanocrystals	nanocrystal	NOUN
admet-1437	21	17	through	through	ADP
admet-1437	21	18	an	an	DET
admet-1437	21	19	optimized	optimize	VERB
admet-1437	21	20	design	design	NOUN
admet-1437	21	21	of	of	ADP
admet-1437	21	22	the	the	DET
admet-1437	21	23	wet	wet	ADJ
admet-1437	21	24	media	media	NOUN
admet-1437	21	25	milling	milling	NOUN
admet-1437	21	26	process	process	NOUN
admet-1437	21	27	[	[	X
admet-1437	21	28	20,21	20,21	NUM
admet-1437	21	29	]	]	PUNCT
admet-1437	21	30	.	.	PUNCT
admet-1437	22	1	the	the	DET
admet-1437	22	2	underlying	underlie	VERB
admet-1437	22	3	mechanisms	mechanism	NOUN
admet-1437	22	4	for	for	ADP
admet-1437	22	5	bioavailability	bioavailability	NOUN
admet-1437	22	6	improvement	improvement	NOUN
admet-1437	22	7	of	of	ADP
admet-1437	22	8	marketed	market	VERB
admet-1437	22	9	oral	oral	ADJ
admet-1437	22	10	nanocrystal	nanocrystal	ADJ
admet-1437	22	11	products	product	NOUN
admet-1437	22	12	were	be	AUX
admet-1437	22	13	investigated	investigate	VERB
admet-1437	22	14	by	by	ADP
admet-1437	22	15	in	in	ADP
admet-1437	22	16	vitro	vitro	X
admet-1437	22	17	/	/	SYM
admet-1437	22	18	in	in	ADP
admet-1437	22	19	silico	silico	NOUN
admet-1437	22	20	endeavors	endeavor	NOUN
admet-1437	22	21	to	to	PART
admet-1437	22	22	retrospectively	retrospectively	ADV
admet-1437	22	23	understand	understand	VERB
admet-1437	22	24	in	in	ADP
admet-1437	22	25	vivo	vivo	ADJ
admet-1437	22	26	absorption	absorption	NOUN
admet-1437	23	1	[	[	X
admet-1437	23	2	11,22	11,22	NUM
admet-1437	23	3	-	-	SYM
admet-1437	23	4	30	30	NUM
admet-1437	23	5	]	]	PUNCT
admet-1437	23	6	.	.	PUNCT
admet-1437	24	1	there	there	PRON
admet-1437	24	2	is	be	VERB
admet-1437	24	3	a	a	DET
admet-1437	24	4	general	general	ADJ
admet-1437	24	5	agreement	agreement	NOUN
admet-1437	24	6	that	that	PRON
admet-1437	24	7	the	the	DET
admet-1437	24	8	increase	increase	NOUN
admet-1437	24	9	of	of	ADP
admet-1437	24	10	the	the	DET
admet-1437	24	11	drug	drug	NOUN
admet-1437	24	12	nanocrystal	nanocrystal	ADJ
admet-1437	24	13	-	-	PUNCT
admet-1437	24	14	specific	specific	ADJ
admet-1437	24	15	surface	surface	NOUN
admet-1437	24	16	area	area	NOUN
admet-1437	24	17	is	be	AUX
admet-1437	24	18	a	a	DET
admet-1437	24	19	contributing	contribute	VERB
admet-1437	24	20	factor	factor	NOUN
admet-1437	24	21	for	for	ADP
admet-1437	24	22	the	the	DET
admet-1437	24	23	dissolution	dissolution	NOUN
admet-1437	24	24	rate	rate	NOUN
admet-1437	24	25	and	and	CCONJ
admet-1437	24	26	the	the	DET
admet-1437	24	27	corresponding	corresponding	ADJ
admet-1437	24	28	bioavailability	bioavailability	NOUN
admet-1437	24	29	improvement	improvement	NOUN
admet-1437	24	30	.	.	PUNCT
admet-1437	25	1	further	far	ADV
admet-1437	25	2	contributing	contribute	VERB
admet-1437	25	3	factors	factor	NOUN
admet-1437	25	4	for	for	ADP
admet-1437	25	5	bioavailability	bioavailability	NOUN
admet-1437	25	6	improvement	improvement	NOUN
admet-1437	25	7	can	can	AUX
admet-1437	25	8	not	not	PART
admet-1437	25	9	always	always	ADV
admet-1437	25	10	be	be	AUX
admet-1437	25	11	fully	fully	ADV
admet-1437	25	12	explained	explain	VERB
admet-1437	25	13	and	and	CCONJ
admet-1437	25	14	hence	hence	ADV
admet-1437	25	15	can	can	AUX
admet-1437	25	16	not	not	PART
admet-1437	25	17	be	be	AUX
admet-1437	25	18	generalized	generalize	VERB
admet-1437	25	19	.	.	PUNCT
admet-1437	26	1	hypothesized	hypothesize	VERB
admet-1437	26	2	additional	additional	ADJ
admet-1437	26	3	factors	factor	NOUN
admet-1437	26	4	include	include	VERB
admet-1437	26	5	,	,	PUNCT
admet-1437	26	6	i.e.	i.e.	X
admet-1437	26	7	,	,	PUNCT
admet-1437	26	8	intestinal	intestinal	ADJ
admet-1437	26	9	absorption	absorption	NOUN
admet-1437	26	10	of	of	ADP
admet-1437	26	11	intact	intact	ADJ
admet-1437	26	12	nanocrystals	nanocrystal	NOUN
admet-1437	26	13	into	into	ADP
admet-1437	26	14	the	the	DET
admet-1437	26	15	enterocytes	enterocyte	NOUN
admet-1437	26	16	,	,	PUNCT
admet-1437	26	17	increased	increase	VERB
admet-1437	26	18	drug	drug	NOUN
admet-1437	26	19	concentration	concentration	NOUN
admet-1437	26	20	at	at	ADP
admet-1437	26	21	the	the	DET
admet-1437	26	22	epithelial	epithelial	ADJ
admet-1437	26	23	surface	surface	NOUN
admet-1437	26	24	,	,	PUNCT
admet-1437	26	25	increased	increase	VERB
admet-1437	26	26	deposition	deposition	NOUN
admet-1437	26	27	and	and	CCONJ
admet-1437	26	28	retention	retention	NOUN
admet-1437	26	29	of	of	ADP
admet-1437	26	30	nanocrystals	nanocrystal	NOUN
admet-1437	26	31	due	due	ADJ
admet-1437	26	32	to	to	ADP
admet-1437	26	33	mucoadhesion	mucoadhesion	NOUN
admet-1437	26	34	and	and	CCONJ
admet-1437	26	35	positive	positive	ADJ
admet-1437	26	36	effects	effect	NOUN
admet-1437	26	37	of	of	ADP
admet-1437	26	38	surfactants	surfactant	NOUN
admet-1437	26	39	on	on	ADP
admet-1437	26	40	drug	drug	NOUN
admet-1437	26	41	solubility	solubility	NOUN
admet-1437	27	1	[	[	X
admet-1437	27	2	11,22,24	11,22,24	NUM
admet-1437	27	3	-	-	SYM
admet-1437	27	4	28	28	NUM
admet-1437	27	5	]	]	PUNCT
admet-1437	27	6	.	.	PUNCT
admet-1437	28	1	supersaturation	supersaturation	NOUN
admet-1437	28	2	from	from	ADP
admet-1437	28	3	ultrafine	ultrafine	NOUN
admet-1437	28	4	nanocrystals	nanocrystal	NOUN
admet-1437	28	5	is	be	AUX
admet-1437	28	6	not	not	PART
admet-1437	28	7	considered	consider	VERB
admet-1437	28	8	a	a	DET
admet-1437	28	9	contributing	contribute	VERB
admet-1437	28	10	factor	factor	NOUN
admet-1437	28	11	to	to	ADP
admet-1437	28	12	bioavailability	bioavailability	NOUN
admet-1437	28	13	improvement	improvement	NOUN
admet-1437	28	14	.	.	PUNCT
admet-1437	29	1	however	however	ADV
admet-1437	29	2	,	,	PUNCT
admet-1437	29	3	there	there	PRON
admet-1437	29	4	is	be	VERB
admet-1437	29	5	no	no	DET
admet-1437	29	6	compelling	compelling	ADJ
admet-1437	29	7	in	in	ADP
admet-1437	29	8	vivo	vivo	ADJ
admet-1437	29	9	evidence	evidence	NOUN
admet-1437	29	10	to	to	PART
admet-1437	29	11	directly	directly	ADV
admet-1437	29	12	validate	validate	VERB
admet-1437	29	13	or	or	CCONJ
admet-1437	29	14	invalidate	invalidate	VERB
admet-1437	29	15	any	any	PRON
admet-1437	29	16	of	of	ADP
admet-1437	29	17	these	these	DET
admet-1437	29	18	further	further	ADJ
admet-1437	29	19	mechanisms	mechanism	NOUN
admet-1437	29	20	.	.	PUNCT
admet-1437	30	1	dissolution	dissolution	ADJ
admet-1437	30	2	kinetics	kinetic	NOUN
admet-1437	30	3	and	and	CCONJ
admet-1437	30	4	dissolution	dissolution	NOUN
admet-1437	30	5	-	-	PUNCT
admet-1437	30	6	permeation	permeation	NOUN
admet-1437	30	7	tests	test	NOUN
admet-1437	30	8	are	be	AUX
admet-1437	30	9	typical	typical	ADJ
admet-1437	30	10	approaches	approach	NOUN
admet-1437	30	11	to	to	PART
admet-1437	30	12	investigate	investigate	VERB
admet-1437	30	13	in	in	ADP
admet-1437	30	14	vitro	vitro	X
admet-1437	30	15	the	the	DET
admet-1437	30	16	contributing	contribute	VERB
admet-1437	30	17	factors	factor	NOUN
admet-1437	30	18	for	for	ADP
admet-1437	30	19	the	the	DET
admet-1437	30	20	potential	potential	ADJ
admet-1437	30	21	bioavailability	bioavailability	NOUN
admet-1437	30	22	improvement	improvement	NOUN
admet-1437	30	23	of	of	ADP
admet-1437	30	24	oral	oral	ADJ
admet-1437	30	25	nanocrystal	nanocrystal	ADJ
admet-1437	30	26	products	product	NOUN
admet-1437	30	27	[	[	X
admet-1437	30	28	31	31	NUM
admet-1437	30	29	-	-	SYM
admet-1437	30	30	41	41	NUM
admet-1437	30	31	]	]	PUNCT
admet-1437	30	32	.	.	PUNCT
admet-1437	31	1	in	in	ADP
admet-1437	31	2	general	general	ADJ
admet-1437	31	3	,	,	PUNCT
admet-1437	31	4	the	the	DET
admet-1437	31	5	dissolution	dissolution	NOUN
admet-1437	31	6	kinetics	kinetic	NOUN
admet-1437	31	7	of	of	ADP
admet-1437	31	8	dispersed	disperse	VERB
admet-1437	31	9	nanocrystals	nanocrystal	NOUN
admet-1437	31	10	takes	take	VERB
admet-1437	31	11	place	place	NOUN
admet-1437	31	12	almost	almost	ADV
admet-1437	31	13	instantaneously	instantaneously	ADV
admet-1437	31	14	,	,	PUNCT
admet-1437	31	15	i.e.	i.e.	X
admet-1437	31	16	,	,	PUNCT
admet-1437	31	17	in	in	ADP
admet-1437	31	18	the	the	DET
admet-1437	31	19	time	time	NOUN
admet-1437	31	20	scale	scale	NOUN
admet-1437	31	21	of	of	ADP
admet-1437	31	22	seconds	second	NOUN
admet-1437	31	23	.	.	PUNCT
admet-1437	32	1	therefore	therefore	ADV
admet-1437	32	2	,	,	PUNCT
admet-1437	32	3	the	the	DET
admet-1437	32	4	discrimination	discrimination	NOUN
admet-1437	32	5	of	of	ADP
admet-1437	32	6	the	the	DET
admet-1437	32	7	dissolution	dissolution	NOUN
admet-1437	32	8	rate	rate	NOUN
admet-1437	32	9	of	of	ADP
admet-1437	32	10	dispersed	disperse	VERB
admet-1437	32	11	nanocrystals	nanocrystal	NOUN
admet-1437	32	12	with	with	ADP
admet-1437	32	13	different	different	ADJ
admet-1437	32	14	particle	particle	NOUN
admet-1437	32	15	sizes	size	NOUN
admet-1437	32	16	,	,	PUNCT
admet-1437	32	17	even	even	ADV
admet-1437	32	18	in	in	ADP
admet-1437	32	19	comparison	comparison	NOUN
admet-1437	32	20	to	to	ADP
admet-1437	32	21	dispersed	disperse	VERB
admet-1437	32	22	microcrystals	microcrystal	NOUN
admet-1437	32	23	,	,	PUNCT
admet-1437	32	24	is	be	AUX
admet-1437	32	25	challenging	challenging	ADJ
admet-1437	32	26	.	.	PUNCT
admet-1437	33	1	furthermore	furthermore	ADV
admet-1437	33	2	,	,	PUNCT
admet-1437	33	3	the	the	DET
admet-1437	33	4	separation	separation	NOUN
admet-1437	33	5	of	of	ADP
admet-1437	33	6	undissolved	undissolved	ADJ
admet-1437	33	7	nanocrystals	nanocrystal	NOUN
admet-1437	33	8	from	from	ADP
admet-1437	33	9	the	the	DET
admet-1437	33	10	dissolved	dissolve	VERB
admet-1437	33	11	drug	drug	NOUN
admet-1437	33	12	for	for	ADP
admet-1437	33	13	the	the	DET
admet-1437	33	14	determination	determination	NOUN
admet-1437	33	15	of	of	ADP
admet-1437	33	16	the	the	DET
admet-1437	33	17	dissolved	dissolve	VERB
admet-1437	33	18	mass	mass	NOUN
admet-1437	33	19	fraction	fraction	NOUN
admet-1437	33	20	is	be	AUX
admet-1437	33	21	considered	consider	VERB
admet-1437	33	22	difficult	difficult	ADJ
admet-1437	33	23	and	and	CCONJ
admet-1437	33	24	reported	report	VERB
admet-1437	33	25	data	datum	NOUN
admet-1437	33	26	in	in	ADP
admet-1437	33	27	the	the	DET
admet-1437	33	28	literature	literature	NOUN
admet-1437	33	29	must	must	AUX
admet-1437	33	30	be	be	AUX
admet-1437	33	31	critically	critically	ADV
admet-1437	33	32	reviewed	review	VERB
admet-1437	33	33	[	[	PUNCT
admet-1437	33	34	8	8	NUM
admet-1437	33	35	]	]	PUNCT
admet-1437	33	36	.	.	PUNCT
admet-1437	34	1	in	in	ADP
admet-1437	34	2	situ	situ	ADJ
admet-1437	34	3	approaches	approach	NOUN
admet-1437	34	4	using	use	VERB
admet-1437	34	5	,	,	PUNCT
admet-1437	34	6	i.e.	i.e.	X
admet-1437	34	7	,	,	PUNCT
admet-1437	34	8	ion	ion	NOUN
admet-1437	34	9	selective	selective	ADJ
admet-1437	34	10	electrodes	electrode	NOUN
admet-1437	34	11	,	,	PUNCT
admet-1437	34	12	second	second	ADJ
admet-1437	34	13	-	-	PUNCT
admet-1437	34	14	derivative	derivative	ADJ
admet-1437	34	15	uv	uv	NOUN
admet-1437	34	16	spectroscopy	spectroscopy	NOUN
admet-1437	34	17	and	and	CCONJ
admet-1437	34	18	dynamic	dynamic	ADJ
admet-1437	34	19	light	light	NOUN
admet-1437	34	20	scattering	scattering	NOUN
admet-1437	34	21	could	could	AUX
admet-1437	34	22	be	be	AUX
admet-1437	34	23	a	a	DET
admet-1437	34	24	possibility	possibility	NOUN
admet-1437	34	25	[	[	X
admet-1437	34	26	29,35,40,41	29,35,40,41	NUM
admet-1437	34	27	]	]	PUNCT
admet-1437	34	28	.	.	PUNCT
admet-1437	35	1	although	although	SCONJ
admet-1437	35	2	it	it	PRON
admet-1437	35	3	must	must	AUX
admet-1437	35	4	be	be	AUX
admet-1437	35	5	borne	bear	VERB
admet-1437	35	6	in	in	ADP
admet-1437	35	7	mind	mind	NOUN
admet-1437	35	8	that	that	SCONJ
admet-1437	35	9	the	the	DET
admet-1437	35	10	interaction	interaction	NOUN
admet-1437	35	11	of	of	ADP
admet-1437	35	12	uv	uv	NOUN
admet-1437	35	13	-	-	PUNCT
admet-1437	35	14	radiation	radiation	NOUN
admet-1437	35	15	with	with	ADP
admet-1437	35	16	ultrafine	ultrafine	NOUN
admet-1437	35	17	nanocrystals	nanocrystal	NOUN
admet-1437	35	18	and	and	CCONJ
admet-1437	35	19	the	the	DET
admet-1437	35	20	poor	poor	ADJ
admet-1437	35	21	time	time	NOUN
admet-1437	35	22	resolution	resolution	NOUN
admet-1437	35	23	for	for	ADP
admet-1437	35	24	uv	uv	NOUN
admet-1437	35	25	spectroscopy	spectroscopy	NOUN
admet-1437	35	26	-	-	PUNCT
admet-1437	35	27	based	base	VERB
admet-1437	35	28	methods	method	NOUN
admet-1437	35	29	are	be	AUX
admet-1437	35	30	still	still	ADV
admet-1437	35	31	challenging	challenge	VERB
admet-1437	35	32	[	[	X
admet-1437	35	33	42	42	NUM
admet-1437	35	34	]	]	PUNCT
admet-1437	35	35	.	.	PUNCT
admet-1437	36	1	dissolution	dissolution	NOUN
admet-1437	36	2	-	-	PUNCT
admet-1437	36	3	permeation	permeation	NOUN
admet-1437	36	4	tests	test	NOUN
admet-1437	36	5	were	be	AUX
admet-1437	36	6	also	also	ADV
admet-1437	36	7	evaluated	evaluate	VERB
admet-1437	36	8	overcoming	overcome	VERB
admet-1437	36	9	the	the	DET
admet-1437	36	10	issue	issue	NOUN
admet-1437	36	11	of	of	ADP
admet-1437	36	12	separation	separation	NOUN
admet-1437	36	13	of	of	ADP
admet-1437	36	14	dissolved	dissolve	VERB
admet-1437	36	15	from	from	ADP
admet-1437	36	16	the	the	DET
admet-1437	36	17	undissolved	undissolve	VERB
admet-1437	36	18	drug	drug	NOUN
admet-1437	36	19	when	when	SCONJ
admet-1437	36	20	relying	rely	VERB
admet-1437	36	21	on	on	ADP
admet-1437	36	22	data	datum	NOUN
admet-1437	36	23	obtained	obtain	VERB
admet-1437	36	24	from	from	ADP
admet-1437	36	25	the	the	DET
admet-1437	36	26	acceptor	acceptor	NOUN
admet-1437	36	27	compartment	compartment	NOUN
admet-1437	37	1	[	[	X
admet-1437	37	2	23,27,29,32	23,27,29,32	NUM
admet-1437	37	3	-	-	SYM
admet-1437	37	4	39	39	NUM
admet-1437	37	5	]	]	PUNCT
admet-1437	37	6	.	.	PUNCT
admet-1437	38	1	these	these	DET
admet-1437	38	2	tests	test	NOUN
admet-1437	38	3	provide	provide	VERB
admet-1437	38	4	an	an	DET
admet-1437	38	5	overall	overall	ADJ
admet-1437	38	6	,	,	PUNCT
admet-1437	38	7	interrelated	interrelated	ADJ
admet-1437	38	8	set	set	NOUN
admet-1437	38	9	of	of	ADP
admet-1437	38	10	information	information	NOUN
admet-1437	38	11	without	without	ADP
admet-1437	38	12	discrimination	discrimination	NOUN
admet-1437	38	13	between	between	ADP
admet-1437	38	14	dissolution	dissolution	NOUN
admet-1437	38	15	and	and	CCONJ
admet-1437	38	16	permeation	permeation	NOUN
admet-1437	38	17	.	.	PUNCT
admet-1437	39	1	case	case	NOUN
admet-1437	39	2	studies	study	NOUN
admet-1437	39	3	provided	provide	VERB
admet-1437	39	4	a	a	DET
admet-1437	39	5	rank	rank	NOUN
admet-1437	39	6	ordering	ordering	NOUN
admet-1437	39	7	for	for	ADP
admet-1437	39	8	different	different	ADJ
admet-1437	39	9	formulations	formulation	NOUN
admet-1437	39	10	with	with	ADP
admet-1437	39	11	often	often	ADV
admet-1437	39	12	promising	promise	VERB
admet-1437	39	13	correlation	correlation	NOUN
admet-1437	39	14	to	to	ADP
admet-1437	39	15	the	the	DET
admet-1437	39	16	related	relate	VERB
admet-1437	39	17	in	in	ADP
admet-1437	39	18	vivo	vivo	ADJ
admet-1437	39	19	absorption	absorption	NOUN
admet-1437	39	20	data	datum	NOUN
admet-1437	39	21	.	.	PUNCT
admet-1437	40	1	however	however	ADV
admet-1437	40	2	,	,	PUNCT
admet-1437	40	3	the	the	DET
admet-1437	40	4	appropriate	appropriate	ADJ
admet-1437	40	5	experimental	experimental	ADJ
admet-1437	40	6	set	set	NOUN
admet-1437	40	7	-	-	PUNCT
admet-1437	40	8	up	up	NOUN
admet-1437	40	9	and	and	CCONJ
admet-1437	40	10	parameters	parameter	NOUN
admet-1437	40	11	of	of	ADP
admet-1437	40	12	the	the	DET
admet-1437	40	13	permeation	permeation	NOUN
admet-1437	40	14	test	test	NOUN
admet-1437	40	15	,	,	PUNCT
admet-1437	40	16	including	include	VERB
admet-1437	40	17	membrane	membrane	NOUN
admet-1437	40	18	properties	property	NOUN
admet-1437	40	19	,	,	PUNCT
admet-1437	40	20	donor	donor	NOUN
admet-1437	40	21	and	and	CCONJ
admet-1437	40	22	acceptor	acceptor	NOUN
admet-1437	40	23	media	medium	NOUN
admet-1437	40	24	,	,	PUNCT
admet-1437	40	25	volume	volume	NOUN
admet-1437	40	26	and	and	CCONJ
admet-1437	40	27	hydrodynamics	hydrodynamic	NOUN
admet-1437	40	28	,	,	PUNCT
admet-1437	40	29	should	should	AUX
admet-1437	40	30	be	be	AUX
admet-1437	40	31	considered	consider	VERB
admet-1437	40	32	[	[	X
admet-1437	40	33	37,39	37,39	NUM
admet-1437	40	34	]	]	PUNCT
admet-1437	40	35	.	.	PUNCT
admet-1437	41	1	supersaturation	supersaturation	NOUN
admet-1437	41	2	,	,	PUNCT
admet-1437	41	3	respectively	respectively	ADV
admet-1437	41	4	the	the	DET
admet-1437	41	5	increase	increase	NOUN
admet-1437	41	6	of	of	ADP
admet-1437	41	7	apparent	apparent	ADJ
admet-1437	41	8	solubility	solubility	NOUN
admet-1437	41	9	in	in	ADP
admet-1437	41	10	relation	relation	NOUN
admet-1437	41	11	to	to	ADP
admet-1437	41	12	the	the	DET
admet-1437	41	13	thermodynamic	thermodynamic	ADJ
admet-1437	41	14	solubility	solubility	NOUN
admet-1437	41	15	due	due	ADP
admet-1437	41	16	to	to	ADP
admet-1437	41	17	nanocrystal	nanocrystal	ADJ
admet-1437	41	18	particle	particle	NOUN
admet-1437	41	19	size	size	NOUN
admet-1437	41	20	,	,	PUNCT
admet-1437	41	21	as	as	SCONJ
admet-1437	41	22	described	describe	VERB
admet-1437	41	23	by	by	ADP
admet-1437	41	24	the	the	DET
admet-1437	41	25	ostwald	ostwald	NOUN
admet-1437	41	26	-	-	PUNCT
admet-1437	41	27	freundlich	freundlich	ADJ
admet-1437	41	28	equation	equation	NOUN
admet-1437	41	29	,	,	PUNCT
admet-1437	41	30	is	be	AUX
admet-1437	41	31	another	another	DET
admet-1437	41	32	potential	potential	ADJ
admet-1437	41	33	contributing	contribute	VERB
admet-1437	41	34	factor	factor	NOUN
admet-1437	41	35	to	to	ADP
admet-1437	41	36	the	the	DET
admet-1437	41	37	bioavailability	bioavailability	NOUN
admet-1437	41	38	improvement	improvement	NOUN
admet-1437	41	39	of	of	ADP
admet-1437	41	40	oral	oral	ADJ
admet-1437	41	41	nanocrystal	nanocrystal	ADJ
admet-1437	41	42	products	product	NOUN
admet-1437	41	43	[	[	X
admet-1437	41	44	8,43	8,43	NUM
admet-1437	41	45	-	-	SYM
admet-1437	41	46	46	46	NUM
admet-1437	41	47	]	]	PUNCT
admet-1437	41	48	.	.	PUNCT
admet-1437	42	1	initial	initial	ADJ
admet-1437	42	2	studies	study	NOUN
admet-1437	42	3	suggested	suggest	VERB
admet-1437	42	4	a	a	DET
admet-1437	42	5	solubility	solubility	NOUN
admet-1437	42	6	increase	increase	NOUN
admet-1437	42	7	due	due	ADP
admet-1437	42	8	to	to	ADP
admet-1437	42	9	nanocrystal	nanocrystal	ADJ
admet-1437	42	10	particle	particle	NOUN
admet-1437	42	11	size	size	NOUN
admet-1437	42	12	from	from	ADP
admet-1437	42	13	marginal	marginal	ADJ
admet-1437	42	14	up	up	ADP
admet-1437	42	15	to	to	ADP
admet-1437	42	16	several	several	ADJ
admet-1437	42	17	folds	fold	NOUN
admet-1437	42	18	.	.	PUNCT
admet-1437	43	1	the	the	DET
admet-1437	43	2	admet	admet	PROPN
admet-1437	43	3	&	&	CCONJ
admet-1437	43	4	dmpk	dmpk	PROPN
admet-1437	43	5	10(4	10(4	NUM
admet-1437	43	6	)	)	PUNCT
admet-1437	43	7	(	(	PUNCT
admet-1437	43	8	2022	2022	NUM
admet-1437	43	9	)	)	PUNCT
admet-1437	43	10	253	253	NUM
admet-1437	43	11	-	-	SYM
admet-1437	43	12	287	287	NUM
admet-1437	43	13	modeling	modeling	NOUN
admet-1437	43	14	of	of	ADP
admet-1437	43	15	drug	drug	NOUN
admet-1437	43	16	nanocrystals	nanocrystal	NOUN
admet-1437	43	17	dissolution	dissolution	NOUN
admet-1437	43	18	doi	doi	PROPN
admet-1437	43	19	:	:	PUNCT
admet-1437	43	20	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	43	21	255	255	NUM
admet-1437	43	22	critical	critical	ADJ
admet-1437	43	23	review	review	NOUN
admet-1437	43	24	of	of	ADP
admet-1437	43	25	the	the	DET
admet-1437	43	26	available	available	ADJ
admet-1437	43	27	reports	report	NOUN
admet-1437	43	28	provided	provide	VERB
admet-1437	43	29	evidence	evidence	NOUN
admet-1437	43	30	that	that	SCONJ
admet-1437	43	31	the	the	DET
admet-1437	43	32	increase	increase	NOUN
admet-1437	43	33	of	of	ADP
admet-1437	43	34	the	the	DET
admet-1437	43	35	apparent	apparent	ADJ
admet-1437	43	36	solubility	solubility	NOUN
admet-1437	43	37	,	,	PUNCT
admet-1437	43	38	in	in	ADP
admet-1437	43	39	relation	relation	NOUN
admet-1437	43	40	to	to	ADP
admet-1437	43	41	the	the	DET
admet-1437	43	42	thermodynamic	thermodynamic	ADJ
admet-1437	43	43	solubility	solubility	NOUN
admet-1437	43	44	,	,	PUNCT
admet-1437	43	45	is	be	AUX
admet-1437	43	46	only	only	ADV
admet-1437	43	47	marginally	marginally	ADV
admet-1437	43	48	of	of	ADP
admet-1437	43	49	up	up	ADP
admet-1437	43	50	to	to	ADP
admet-1437	43	51	about	about	ADP
admet-1437	43	52	15	15	NUM
admet-1437	43	53	to	to	PART
admet-1437	43	54	20	20	NUM
admet-1437	43	55	%	%	NOUN
admet-1437	43	56	for	for	ADP
admet-1437	43	57	the	the	DET
admet-1437	43	58	finest	fine	ADJ
admet-1437	43	59	mean	mean	ADJ
admet-1437	43	60	nanocrystal	nanocrystal	ADJ
admet-1437	43	61	particle	particle	NOUN
admet-1437	43	62	size	size	NOUN
admet-1437	43	63	of	of	ADP
admet-1437	43	64	about	about	ADV
admet-1437	43	65	150	150	NUM
admet-1437	43	66	nm	nm	NOUN
admet-1437	43	67	[	[	X
admet-1437	43	68	8,43	8,43	NUM
admet-1437	43	69	-	-	SYM
admet-1437	43	70	46	46	NUM
admet-1437	43	71	]	]	PUNCT
admet-1437	43	72	.	.	PUNCT
admet-1437	44	1	the	the	DET
admet-1437	44	2	reason	reason	NOUN
admet-1437	44	3	for	for	ADP
admet-1437	44	4	the	the	DET
admet-1437	44	5	discrepancy	discrepancy	NOUN
admet-1437	44	6	in	in	ADP
admet-1437	44	7	the	the	DET
admet-1437	44	8	available	available	ADJ
admet-1437	44	9	reports	report	NOUN
admet-1437	44	10	was	be	AUX
admet-1437	44	11	mainly	mainly	ADV
admet-1437	44	12	associated	associate	VERB
admet-1437	44	13	with	with	ADP
admet-1437	44	14	inadequate	inadequate	ADJ
admet-1437	44	15	methods	method	NOUN
admet-1437	44	16	for	for	ADP
admet-1437	44	17	the	the	DET
admet-1437	44	18	separation	separation	NOUN
admet-1437	44	19	of	of	ADP
admet-1437	44	20	dissolved	dissolved	ADJ
admet-1437	44	21	drug	drug	NOUN
admet-1437	44	22	from	from	ADP
admet-1437	44	23	undissolved	undissolve	VERB
admet-1437	44	24	drug	drug	NOUN
admet-1437	44	25	nanocrystals	nanocrystal	NOUN
admet-1437	44	26	[	[	X
admet-1437	44	27	8	8	NUM
admet-1437	44	28	]	]	PUNCT
admet-1437	44	29	.	.	PUNCT
admet-1437	45	1	in	in	ADP
admet-1437	45	2	conclusion	conclusion	NOUN
admet-1437	45	3	,	,	PUNCT
admet-1437	45	4	there	there	PRON
admet-1437	45	5	is	be	VERB
admet-1437	45	6	the	the	DET
admet-1437	45	7	general	general	ADJ
admet-1437	45	8	agreement	agreement	NOUN
admet-1437	45	9	that	that	PRON
admet-1437	45	10	dissolution	dissolution	ADJ
admet-1437	45	11	rate	rate	NOUN
admet-1437	45	12	is	be	AUX
admet-1437	45	13	a	a	DET
admet-1437	45	14	contributing	contribute	VERB
admet-1437	45	15	factor	factor	NOUN
admet-1437	45	16	and	and	CCONJ
admet-1437	45	17	supersaturation	supersaturation	NOUN
admet-1437	45	18	is	be	AUX
admet-1437	45	19	of	of	ADP
admet-1437	45	20	secondary	secondary	ADJ
admet-1437	45	21	importance	importance	NOUN
admet-1437	45	22	for	for	ADP
admet-1437	45	23	bioavailability	bioavailability	NOUN
admet-1437	45	24	improvement	improvement	NOUN
admet-1437	45	25	.	.	PUNCT
admet-1437	46	1	the	the	DET
admet-1437	46	2	bioavailability	bioavailability	NOUN
admet-1437	46	3	improvement	improvement	NOUN
admet-1437	46	4	due	due	ADP
admet-1437	46	5	to	to	ADP
admet-1437	46	6	the	the	DET
admet-1437	46	7	projected	project	VERB
admet-1437	46	8	increase	increase	NOUN
admet-1437	46	9	of	of	ADP
admet-1437	46	10	the	the	DET
admet-1437	46	11	apparent	apparent	ADJ
admet-1437	46	12	solubility	solubility	NOUN
admet-1437	46	13	by	by	ADP
admet-1437	46	14	the	the	DET
admet-1437	46	15	ostwald	ostwald	NOUN
admet-1437	46	16	-	-	PUNCT
admet-1437	46	17	freundlich	freundlich	ADJ
admet-1437	46	18	equation	equation	NOUN
admet-1437	46	19	is	be	AUX
admet-1437	46	20	hypothesized	hypothesize	VERB
admet-1437	46	21	to	to	PART
admet-1437	46	22	be	be	AUX
admet-1437	46	23	more	more	ADV
admet-1437	46	24	pronounced	pronounce	VERB
admet-1437	46	25	only	only	ADV
admet-1437	46	26	for	for	ADP
admet-1437	46	27	nanocrystal	nanocrystal	ADJ
admet-1437	46	28	particle	particle	NOUN
admet-1437	46	29	sizes	size	NOUN
admet-1437	46	30	in	in	ADP
admet-1437	46	31	the	the	DET
admet-1437	46	32	50	50	NUM
admet-1437	46	33	nm	nm	ADJ
admet-1437	46	34	range	range	NOUN
admet-1437	46	35	[	[	X
admet-1437	46	36	8	8	NUM
admet-1437	46	37	]	]	PUNCT
admet-1437	46	38	.	.	PUNCT
admet-1437	47	1	dissolution	dissolution	PROPN
admet-1437	47	2	modeling	modeling	NOUN
admet-1437	47	3	is	be	AUX
admet-1437	47	4	a	a	DET
admet-1437	47	5	well	well	ADV
admet-1437	47	6	-	-	PUNCT
admet-1437	47	7	established	establish	VERB
admet-1437	47	8	in	in	ADP
admet-1437	47	9	silico	silico	NOUN
admet-1437	47	10	approach	approach	NOUN
admet-1437	47	11	to	to	PART
admet-1437	47	12	mathematically	mathematically	ADV
admet-1437	47	13	describe	describe	VERB
admet-1437	47	14	the	the	DET
admet-1437	47	15	diffusionlimited	diffusionlimite	VERB
admet-1437	47	16	release	release	NOUN
admet-1437	47	17	from	from	ADP
admet-1437	47	18	drug	drug	NOUN
admet-1437	47	19	particles	particle	NOUN
admet-1437	47	20	for	for	ADP
admet-1437	47	21	coarse	coarse	NOUN
admet-1437	47	22	and	and	CCONJ
admet-1437	47	23	micron	micron	NOUN
admet-1437	47	24	particle	particle	NOUN
admet-1437	47	25	sizes	size	NOUN
admet-1437	47	26	considering	consider	VERB
admet-1437	47	27	the	the	DET
admet-1437	47	28	complex	complex	ADJ
admet-1437	47	29	interplay	interplay	NOUN
admet-1437	47	30	of	of	ADP
admet-1437	47	31	relevant	relevant	ADJ
admet-1437	47	32	parameters	parameter	NOUN
admet-1437	47	33	such	such	ADJ
admet-1437	47	34	as	as	ADP
admet-1437	47	35	drug	drug	NOUN
admet-1437	47	36	amount	amount	NOUN
admet-1437	47	37	,	,	PUNCT
admet-1437	47	38	particle	particle	NOUN
admet-1437	47	39	size	size	NOUN
admet-1437	47	40	,	,	PUNCT
admet-1437	47	41	shape	shape	NOUN
admet-1437	47	42	,	,	PUNCT
admet-1437	47	43	as	as	ADV
admet-1437	47	44	well	well	ADV
admet-1437	47	45	as	as	ADP
admet-1437	47	46	dissolution	dissolution	ADJ
admet-1437	47	47	media	medium	NOUN
admet-1437	47	48	and	and	CCONJ
admet-1437	47	49	related	related	ADJ
admet-1437	47	50	volume	volume	NOUN
admet-1437	47	51	[	[	X
admet-1437	47	52	47	47	NUM
admet-1437	47	53	-	-	SYM
admet-1437	47	54	52	52	NUM
admet-1437	47	55	]	]	PUNCT
admet-1437	47	56	.	.	PUNCT
admet-1437	48	1	in	in	ADP
admet-1437	48	2	contrast	contrast	NOUN
admet-1437	48	3	,	,	PUNCT
admet-1437	48	4	dissolution	dissolution	ADJ
admet-1437	48	5	modeling	modeling	NOUN
admet-1437	48	6	from	from	ADP
admet-1437	48	7	drug	drug	NOUN
admet-1437	48	8	nanocrystals	nanocrystal	NOUN
admet-1437	48	9	is	be	AUX
admet-1437	48	10	reported	report	VERB
admet-1437	48	11	only	only	ADV
admet-1437	48	12	by	by	ADP
admet-1437	48	13	a	a	DET
admet-1437	48	14	limited	limited	ADJ
admet-1437	48	15	number	number	NOUN
admet-1437	48	16	of	of	ADP
admet-1437	48	17	studies	study	NOUN
admet-1437	48	18	[	[	X
admet-1437	48	19	30,53	30,53	NUM
admet-1437	48	20	-	-	SYM
admet-1437	48	21	55	55	NUM
admet-1437	48	22	]	]	PUNCT
admet-1437	48	23	.	.	PUNCT
admet-1437	49	1	liu	liu	PROPN
admet-1437	49	2	et	et	PROPN
admet-1437	49	3	al	al	PROPN
admet-1437	49	4	.	.	PROPN
admet-1437	49	5	simulated	simulate	VERB
admet-1437	49	6	the	the	DET
admet-1437	49	7	dissolution	dissolution	NOUN
admet-1437	49	8	of	of	ADP
admet-1437	49	9	monodisperse	monodisperse	NOUN
admet-1437	49	10	particles	particle	NOUN
admet-1437	49	11	with	with	ADP
admet-1437	49	12	a	a	DET
admet-1437	49	13	size	size	NOUN
admet-1437	49	14	of	of	ADP
admet-1437	49	15	1300	1300	NUM
admet-1437	49	16	,	,	PUNCT
admet-1437	49	17	560	560	NUM
admet-1437	49	18	and	and	CCONJ
admet-1437	49	19	340	340	NUM
admet-1437	49	20	nm	nm	NOUN
admet-1437	49	21	,	,	PUNCT
admet-1437	49	22	not	not	PART
admet-1437	49	23	considering	consider	VERB
admet-1437	49	24	the	the	DET
admet-1437	49	25	increase	increase	NOUN
admet-1437	49	26	of	of	ADP
admet-1437	49	27	the	the	DET
admet-1437	49	28	apparent	apparent	ADJ
admet-1437	49	29	solubility	solubility	NOUN
admet-1437	49	30	[	[	X
admet-1437	49	31	30	30	NUM
admet-1437	49	32	]	]	PUNCT
admet-1437	49	33	.	.	PUNCT
admet-1437	50	1	ely	ely	ADV
admet-1437	50	2	et	et	PROPN
admet-1437	50	3	al	al	PROPN
admet-1437	50	4	.	.	PROPN
admet-1437	50	5	provided	provide	VERB
admet-1437	50	6	the	the	DET
admet-1437	50	7	theoretical	theoretical	ADJ
admet-1437	50	8	framework	framework	NOUN
admet-1437	50	9	to	to	PART
admet-1437	50	10	estimate	estimate	VERB
admet-1437	50	11	the	the	DET
admet-1437	50	12	dissolution	dissolution	NOUN
admet-1437	50	13	kinetics	kinetic	NOUN
admet-1437	50	14	of	of	ADP
admet-1437	50	15	monodisperse	monodisperse	NOUN
admet-1437	50	16	nanocrystals	nanocrystal	NOUN
admet-1437	50	17	considering	consider	VERB
admet-1437	50	18	the	the	DET
admet-1437	50	19	increase	increase	NOUN
admet-1437	50	20	of	of	ADP
admet-1437	50	21	the	the	DET
admet-1437	50	22	apparent	apparent	ADJ
admet-1437	50	23	solubility	solubility	NOUN
admet-1437	50	24	by	by	ADP
admet-1437	50	25	the	the	DET
admet-1437	50	26	ostwald	ostwald	NOUN
admet-1437	50	27	-	-	PUNCT
admet-1437	50	28	freundlich	freundlich	ADJ
admet-1437	50	29	equation	equation	NOUN
admet-1437	50	30	with	with	ADP
admet-1437	50	31	the	the	DET
admet-1437	50	32	assumption	assumption	NOUN
admet-1437	50	33	of	of	ADP
admet-1437	50	34	a	a	DET
admet-1437	50	35	constant	constant	ADJ
admet-1437	50	36	diffusion	diffusion	NOUN
admet-1437	50	37	boundary	boundary	ADJ
admet-1437	50	38	layer	layer	NOUN
admet-1437	50	39	thickness	thickness	NOUN
admet-1437	51	1	[	[	X
admet-1437	51	2	53	53	NUM
admet-1437	51	3	]	]	PUNCT
admet-1437	51	4	.	.	PUNCT
admet-1437	52	1	johnson	johnson	PROPN
admet-1437	52	2	simulated	simulate	VERB
admet-1437	52	3	the	the	DET
admet-1437	52	4	dissolution	dissolution	NOUN
admet-1437	52	5	of	of	ADP
admet-1437	52	6	polydisperse	polydisperse	NOUN
admet-1437	52	7	particle	particle	NOUN
admet-1437	52	8	size	size	NOUN
admet-1437	52	9	distributions	distribution	NOUN
admet-1437	52	10	considering	consider	VERB
admet-1437	52	11	the	the	DET
admet-1437	52	12	increase	increase	NOUN
admet-1437	52	13	of	of	ADP
admet-1437	52	14	the	the	DET
admet-1437	52	15	apparent	apparent	ADJ
admet-1437	52	16	solubility	solubility	NOUN
admet-1437	52	17	according	accord	VERB
admet-1437	52	18	to	to	ADP
admet-1437	52	19	the	the	DET
admet-1437	52	20	ostwald	ostwald	NOUN
admet-1437	52	21	-	-	PUNCT
admet-1437	52	22	freundlich	freundlich	ADJ
admet-1437	52	23	equation	equation	NOUN
admet-1437	52	24	[	[	X
admet-1437	52	25	54	54	NUM
admet-1437	52	26	]	]	PUNCT
admet-1437	52	27	.	.	PUNCT
admet-1437	53	1	he	he	PRON
admet-1437	53	2	provided	provide	VERB
admet-1437	53	3	simulation	simulation	NOUN
admet-1437	53	4	results	result	NOUN
admet-1437	53	5	for	for	ADP
admet-1437	53	6	the	the	DET
admet-1437	53	7	dissolution	dissolution	NOUN
admet-1437	53	8	of	of	ADP
admet-1437	53	9	coarse	coarse	NOUN
admet-1437	53	10	and	and	CCONJ
admet-1437	53	11	micron	micron	NOUN
admet-1437	53	12	-	-	PUNCT
admet-1437	53	13	sized	sized	ADJ
admet-1437	53	14	particle	particle	NOUN
admet-1437	53	15	size	size	NOUN
admet-1437	53	16	distributions	distribution	NOUN
admet-1437	53	17	and	and	CCONJ
admet-1437	53	18	used	use	VERB
admet-1437	53	19	experimental	experimental	ADJ
admet-1437	53	20	dissolution	dissolution	NOUN
admet-1437	53	21	data	datum	NOUN
admet-1437	53	22	for	for	ADP
admet-1437	53	23	model	model	NOUN
admet-1437	53	24	fitting	fit	VERB
admet-1437	53	25	,	,	PUNCT
admet-1437	53	26	taking	take	VERB
admet-1437	53	27	the	the	DET
admet-1437	53	28	diffusion	diffusion	NOUN
admet-1437	53	29	boundary	boundary	ADJ
admet-1437	53	30	layer	layer	NOUN
admet-1437	53	31	thickness	thickness	NOUN
admet-1437	53	32	as	as	ADP
admet-1437	53	33	a	a	DET
admet-1437	53	34	fit	fit	ADJ
admet-1437	53	35	parameter	parameter	NOUN
admet-1437	53	36	.	.	PUNCT
admet-1437	54	1	parks	park	NOUN
admet-1437	54	2	et	et	PROPN
admet-1437	54	3	al	al	PROPN
admet-1437	54	4	.	.	PROPN
admet-1437	54	5	presented	present	VERB
admet-1437	54	6	a	a	DET
admet-1437	54	7	molecular	molecular	ADJ
admet-1437	54	8	dynamics	dynamic	NOUN
admet-1437	54	9	-	-	PUNCT
admet-1437	54	10	based	base	VERB
admet-1437	54	11	simulation	simulation	NOUN
admet-1437	54	12	methodology	methodology	NOUN
admet-1437	54	13	on	on	ADP
admet-1437	54	14	an	an	DET
admet-1437	54	15	atomistic	atomistic	ADJ
admet-1437	54	16	level	level	NOUN
admet-1437	54	17	and	and	CCONJ
admet-1437	54	18	showed	show	VERB
admet-1437	54	19	results	result	NOUN
admet-1437	54	20	for	for	ADP
admet-1437	54	21	the	the	DET
admet-1437	54	22	dissolution	dissolution	NOUN
admet-1437	54	23	of	of	ADP
admet-1437	54	24	nanocrystals	nanocrystal	NOUN
admet-1437	54	25	with	with	ADP
admet-1437	54	26	particle	particle	NOUN
admet-1437	54	27	sizes	size	NOUN
admet-1437	54	28	below	below	ADP
admet-1437	54	29	6	6	NUM
admet-1437	54	30	nm	nm	NOUN
admet-1437	54	31	[	[	X
admet-1437	54	32	55	55	NUM
admet-1437	54	33	]	]	PUNCT
admet-1437	54	34	.	.	PUNCT
admet-1437	55	1	the	the	DET
admet-1437	55	2	objective	objective	NOUN
admet-1437	55	3	of	of	ADP
admet-1437	55	4	this	this	DET
admet-1437	55	5	study	study	NOUN
admet-1437	55	6	was	be	AUX
admet-1437	55	7	to	to	PART
admet-1437	55	8	manufacture	manufacture	VERB
admet-1437	55	9	a	a	DET
admet-1437	55	10	wide	wide	ADJ
admet-1437	55	11	range	range	NOUN
admet-1437	55	12	of	of	ADP
admet-1437	55	13	nanocrystal	nanocrystal	ADJ
admet-1437	55	14	particle	particle	NOUN
admet-1437	55	15	sizes	size	NOUN
admet-1437	55	16	by	by	ADP
admet-1437	55	17	wet	wet	ADJ
admet-1437	55	18	media	medium	NOUN
admet-1437	55	19	milling	mill	VERB
admet-1437	55	20	technology	technology	NOUN
admet-1437	55	21	with	with	ADP
admet-1437	55	22	identical	identical	ADJ
admet-1437	55	23	drug	drug	NOUN
admet-1437	55	24	compound	compound	NOUN
admet-1437	55	25	and	and	CCONJ
admet-1437	55	26	formulation	formulation	NOUN
admet-1437	55	27	composition	composition	NOUN
admet-1437	55	28	,	,	PUNCT
admet-1437	55	29	including	include	VERB
admet-1437	55	30	sub-100	sub-100	ADJ
admet-1437	55	31	nm	nm	PRON
admet-1437	55	32	particle	particle	NOUN
admet-1437	55	33	sizes	size	NOUN
admet-1437	55	34	using	use	VERB
admet-1437	55	35	an	an	DET
admet-1437	55	36	industrially	industrially	ADV
admet-1437	55	37	applicable	applicable	ADJ
admet-1437	55	38	process	process	NOUN
admet-1437	55	39	design	design	NOUN
admet-1437	55	40	.	.	PUNCT
admet-1437	56	1	the	the	DET
admet-1437	56	2	manufactured	manufacture	VERB
admet-1437	56	3	drug	drug	NOUN
admet-1437	56	4	nanocrystals	nanocrystal	NOUN
admet-1437	56	5	were	be	AUX
admet-1437	56	6	characterized	characterize	VERB
admet-1437	56	7	for	for	ADP
admet-1437	56	8	their	their	PRON
admet-1437	56	9	product	product	NOUN
admet-1437	56	10	attributes	attribute	VERB
admet-1437	56	11	,	,	PUNCT
admet-1437	56	12	namely	namely	ADV
admet-1437	56	13	particle	particle	NOUN
admet-1437	56	14	size	size	NOUN
admet-1437	56	15	distribution	distribution	NOUN
admet-1437	56	16	,	,	PUNCT
admet-1437	56	17	morphology	morphology	NOUN
admet-1437	56	18	and	and	CCONJ
admet-1437	56	19	solid	solid	ADJ
admet-1437	56	20	-	-	PUNCT
admet-1437	56	21	state	state	NOUN
admet-1437	56	22	properties	property	NOUN
admet-1437	56	23	.	.	PUNCT
admet-1437	57	1	subsequently	subsequently	ADV
admet-1437	57	2	,	,	PUNCT
admet-1437	57	3	the	the	DET
admet-1437	57	4	different	different	ADJ
admet-1437	57	5	batches	batch	NOUN
admet-1437	57	6	were	be	AUX
admet-1437	57	7	experimentally	experimentally	ADV
admet-1437	57	8	characterized	characterize	VERB
admet-1437	57	9	for	for	ADP
admet-1437	57	10	their	their	PRON
admet-1437	57	11	apparent	apparent	ADJ
admet-1437	57	12	solubility	solubility	NOUN
admet-1437	57	13	in	in	ADP
admet-1437	57	14	different	different	ADJ
admet-1437	57	15	dissolution	dissolution	NOUN
admet-1437	57	16	media	medium	NOUN
admet-1437	57	17	.	.	PUNCT
admet-1437	58	1	the	the	DET
admet-1437	58	2	experimental	experimental	ADJ
admet-1437	58	3	data	datum	NOUN
admet-1437	58	4	set	set	VERB
admet-1437	58	5	comprising	comprise	VERB
admet-1437	58	6	different	different	ADJ
admet-1437	58	7	drug	drug	NOUN
admet-1437	58	8	nanocrystal	nanocrystal	ADJ
admet-1437	58	9	particle	particle	NOUN
admet-1437	58	10	size	size	NOUN
admet-1437	58	11	distributions	distribution	NOUN
admet-1437	58	12	and	and	CCONJ
admet-1437	58	13	their	their	PRON
admet-1437	58	14	related	relate	VERB
admet-1437	58	15	apparent	apparent	ADJ
admet-1437	58	16	solubility	solubility	NOUN
admet-1437	58	17	were	be	AUX
admet-1437	58	18	used	use	VERB
admet-1437	58	19	to	to	PART
admet-1437	58	20	develop	develop	VERB
admet-1437	58	21	a	a	DET
admet-1437	58	22	numerical	numerical	ADJ
admet-1437	58	23	model	model	NOUN
admet-1437	58	24	for	for	ADP
admet-1437	58	25	the	the	DET
admet-1437	58	26	in	in	ADP
admet-1437	58	27	silico	silico	NOUN
admet-1437	58	28	calculation	calculation	NOUN
admet-1437	58	29	of	of	ADP
admet-1437	58	30	the	the	DET
admet-1437	58	31	dissolution	dissolution	NOUN
admet-1437	58	32	kinetics	kinetic	NOUN
admet-1437	58	33	of	of	ADP
admet-1437	58	34	drug	drug	NOUN
admet-1437	58	35	nanocrystals	nanocrystal	NOUN
admet-1437	58	36	according	accord	VERB
admet-1437	58	37	to	to	ADP
admet-1437	58	38	the	the	DET
admet-1437	58	39	noyes	noyes	PROPN
admet-1437	58	40	-	-	PUNCT
admet-1437	58	41	whitney	whitney	PROPN
admet-1437	58	42	/	/	SYM
admet-1437	58	43	nernst	nernst	PROPN
admet-1437	58	44	-	-	PUNCT
admet-1437	58	45	brunner	brunner	PROPN
admet-1437	58	46	and	and	CCONJ
admet-1437	58	47	ostwald	ostwald	NOUN
admet-1437	58	48	-	-	PUNCT
admet-1437	58	49	freundlich	freundlich	ADJ
admet-1437	58	50	equations	equation	NOUN
admet-1437	58	51	.	.	PUNCT
admet-1437	59	1	the	the	DET
admet-1437	59	2	numerical	numerical	ADJ
admet-1437	59	3	model	model	NOUN
admet-1437	59	4	was	be	AUX
admet-1437	59	5	then	then	ADV
admet-1437	59	6	applied	apply	VERB
admet-1437	59	7	to	to	ADP
admet-1437	59	8	selected	select	VERB
admet-1437	59	9	industrially	industrially	ADV
admet-1437	59	10	relevant	relevant	ADJ
admet-1437	59	11	in	in	ADP
admet-1437	59	12	vivo	vivo	NOUN
admet-1437	59	13	and	and	CCONJ
admet-1437	59	14	in	in	ADP
admet-1437	59	15	vitro	vitro	X
admet-1437	59	16	scenarios	scenario	NOUN
admet-1437	59	17	to	to	PART
admet-1437	59	18	predict	predict	VERB
admet-1437	59	19	in	in	ADP
admet-1437	59	20	silico	silico	NOUN
admet-1437	59	21	the	the	DET
admet-1437	59	22	dissolution	dissolution	NOUN
admet-1437	59	23	in	in	ADP
admet-1437	59	24	a	a	DET
admet-1437	59	25	closed	closed	ADJ
admet-1437	59	26	system	system	NOUN
admet-1437	59	27	considering	consider	VERB
admet-1437	59	28	the	the	DET
admet-1437	59	29	interplay	interplay	NOUN
admet-1437	59	30	between	between	ADP
admet-1437	59	31	input	input	NOUN
admet-1437	59	32	parameters	parameter	NOUN
admet-1437	59	33	:	:	PUNCT
admet-1437	59	34	drug	drug	NOUN
admet-1437	59	35	nanocrystal	nanocrystal	ADJ
admet-1437	59	36	particle	particle	NOUN
admet-1437	59	37	size	size	NOUN
admet-1437	59	38	distribution	distribution	NOUN
admet-1437	59	39	,	,	PUNCT
admet-1437	59	40	drug	drug	NOUN
admet-1437	59	41	amount	amount	NOUN
admet-1437	59	42	,	,	PUNCT
admet-1437	59	43	dissolution	dissolution	NOUN
admet-1437	59	44	media	medium	NOUN
admet-1437	59	45	and	and	CCONJ
admet-1437	59	46	related	related	ADJ
admet-1437	59	47	volume	volume	NOUN
admet-1437	59	48	,	,	PUNCT
admet-1437	59	49	and	and	CCONJ
admet-1437	59	50	output	output	NOUN
admet-1437	59	51	parameters	parameter	NOUN
admet-1437	59	52	:	:	PUNCT
admet-1437	59	53	apparent	apparent	ADJ
admet-1437	59	54	solubility	solubility	NOUN
admet-1437	59	55	,	,	PUNCT
admet-1437	59	56	remaining	remaining	ADJ
admet-1437	59	57	drug	drug	NOUN
admet-1437	59	58	particle	particle	NOUN
admet-1437	59	59	size	size	NOUN
admet-1437	59	60	distribution	distribution	NOUN
admet-1437	59	61	if	if	SCONJ
admet-1437	59	62	any	any	PRON
admet-1437	59	63	and	and	CCONJ
admet-1437	59	64	drug	drug	NOUN
admet-1437	59	65	fraction	fraction	NOUN
admet-1437	59	66	dissolved	dissolve	VERB
admet-1437	59	67	,	,	PUNCT
admet-1437	59	68	all	all	PRON
admet-1437	59	69	time	time	NOUN
admet-1437	59	70	-	-	PUNCT
admet-1437	59	71	resolved	resolve	VERB
admet-1437	59	72	up	up	ADP
admet-1437	59	73	to	to	ADP
admet-1437	59	74	equilibrium	equilibrium	NOUN
admet-1437	59	75	condition	condition	NOUN
admet-1437	59	76	.	.	PUNCT
admet-1437	60	1	experimental	experimental	ADJ
admet-1437	60	2	materials	material	NOUN
admet-1437	60	3	a	a	DET
admet-1437	60	4	proprietary	proprietary	ADJ
admet-1437	60	5	crystalline	crystalline	NOUN
admet-1437	60	6	drug	drug	NOUN
admet-1437	60	7	provided	provide	VERB
admet-1437	60	8	by	by	ADP
admet-1437	60	9	novartis	novartis	PROPN
admet-1437	60	10	pharma	pharma	PROPN
admet-1437	60	11	ag	ag	PROPN
admet-1437	60	12	was	be	AUX
admet-1437	60	13	used	use	VERB
admet-1437	60	14	for	for	ADP
admet-1437	60	15	this	this	DET
admet-1437	60	16	study	study	NOUN
admet-1437	60	17	.	.	PUNCT
admet-1437	61	1	the	the	DET
admet-1437	61	2	compound	compound	NOUN
admet-1437	61	3	is	be	AUX
admet-1437	61	4	a	a	DET
admet-1437	61	5	weak	weak	ADJ
admet-1437	61	6	base	base	NOUN
admet-1437	61	7	showing	show	VERB
admet-1437	61	8	high	high	ADJ
admet-1437	61	9	permeability	permeability	NOUN
admet-1437	61	10	and	and	CCONJ
admet-1437	61	11	low	low	ADJ
admet-1437	61	12	solubility	solubility	NOUN
admet-1437	61	13	at	at	ADP
admet-1437	61	14	physiological	physiological	ADJ
admet-1437	61	15	ph	ph	NOUN
admet-1437	61	16	with	with	ADP
admet-1437	61	17	a	a	DET
admet-1437	61	18	molecular	molecular	ADJ
admet-1437	61	19	weight	weight	NOUN
admet-1437	61	20	above	above	ADP
admet-1437	61	21	500	500	NUM
admet-1437	61	22	g	g	NOUN
admet-1437	61	23	/	/	SYM
admet-1437	61	24	mol	mol	NOUN
admet-1437	61	25	,	,	PUNCT
admet-1437	61	26	a	a	DET
admet-1437	61	27	melting	melting	NOUN
admet-1437	61	28	point	point	NOUN
admet-1437	61	29	above	above	ADP
admet-1437	61	30	180	180	NUM
admet-1437	61	31	°	°	NOUN
admet-1437	61	32	c	c	NOUN
admet-1437	61	33	and	and	CCONJ
admet-1437	61	34	water	water	NOUN
admet-1437	61	35	solubility	solubility	NOUN
admet-1437	61	36	below	below	ADP
admet-1437	61	37	0.1	0.1	NUM
admet-1437	61	38	mg	mg	PROPN
admet-1437	61	39	/	/	SYM
admet-1437	61	40	ml	ml	NOUN
admet-1437	61	41	.	.	PUNCT
admet-1437	62	1	a	a	DET
admet-1437	62	2	typical	typical	ADJ
admet-1437	62	3	polymer	polymer	NOUN
admet-1437	62	4	and	and	CCONJ
admet-1437	62	5	a	a	DET
admet-1437	62	6	surfactant	surfactant	NOUN
admet-1437	62	7	are	be	AUX
admet-1437	62	8	used	use	VERB
admet-1437	62	9	for	for	ADP
admet-1437	62	10	the	the	DET
admet-1437	62	11	stabilization	stabilization	NOUN
admet-1437	62	12	of	of	ADP
admet-1437	62	13	the	the	DET
admet-1437	62	14	nanocrystal	nanocrystal	ADJ
admet-1437	62	15	suspension	suspension	NOUN
admet-1437	62	16	,	,	PUNCT
admet-1437	62	17	according	accord	VERB
admet-1437	62	18	to	to	ADP
admet-1437	62	19	the	the	DET
admet-1437	62	20	literature	literature	NOUN
admet-1437	62	21	[	[	X
admet-1437	62	22	15	15	NUM
admet-1437	62	23	-	-	SYM
admet-1437	62	24	19	19	NUM
admet-1437	62	25	]	]	PUNCT
admet-1437	62	26	.	.	PUNCT
admet-1437	63	1	purified	purified	ADJ
admet-1437	63	2	water	water	NOUN
admet-1437	63	3	was	be	AUX
admet-1437	63	4	used	use	VERB
admet-1437	63	5	throughout	throughout	ADP
admet-1437	63	6	all	all	DET
admet-1437	63	7	experiments	experiment	NOUN
admet-1437	63	8	as	as	ADP
admet-1437	63	9	the	the	DET
admet-1437	63	10	continuous	continuous	ADJ
admet-1437	63	11	phase	phase	NOUN
admet-1437	63	12	for	for	ADP
admet-1437	63	13	nanocrystal	nanocrystal	ADJ
admet-1437	63	14	manufacturing	manufacturing	NOUN
admet-1437	63	15	.	.	PUNCT
admet-1437	64	1	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	X
admet-1437	64	2	bonhoeffer	bonhoeffer	PROPN
admet-1437	64	3	et	et	PROPN
admet-1437	64	4	al	al	PROPN
admet-1437	64	5	.	.	PROPN
admet-1437	64	6	admet	admet	PROPN
admet-1437	64	7	&	&	CCONJ
admet-1437	64	8	dmpk	dmpk	PROPN
admet-1437	64	9	10(4	10(4	NUM
admet-1437	64	10	)	)	PUNCT
admet-1437	64	11	(	(	PUNCT
admet-1437	64	12	2022	2022	NUM
admet-1437	64	13	)	)	PUNCT
admet-1437	64	14	253	253	NUM
admet-1437	64	15	-	-	SYM
admet-1437	64	16	287	287	NUM
admet-1437	64	17	256	256	NUM
admet-1437	64	18	experimental	experimental	ADJ
admet-1437	64	19	methods	method	NOUN
admet-1437	64	20	drug	drug	NOUN
admet-1437	64	21	nanocrystals	nanocrystal	NOUN
admet-1437	64	22	were	be	AUX
admet-1437	64	23	manufactured	manufacture	VERB
admet-1437	64	24	in	in	ADP
admet-1437	64	25	aqueous	aqueous	ADJ
admet-1437	64	26	suspension	suspension	NOUN
admet-1437	64	27	using	use	VERB
admet-1437	64	28	wet	wet	ADJ
admet-1437	64	29	media	medium	NOUN
admet-1437	64	30	milling	mill	VERB
admet-1437	64	31	technology	technology	NOUN
admet-1437	64	32	in	in	ADP
admet-1437	64	33	recirculation	recirculation	NOUN
admet-1437	64	34	mode	mode	NOUN
admet-1437	64	35	.	.	PUNCT
admet-1437	65	1	the	the	DET
admet-1437	65	2	drug	drug	NOUN
admet-1437	65	3	and	and	CCONJ
admet-1437	65	4	stabilizer	stabilizer	NOUN
admet-1437	65	5	composition	composition	NOUN
admet-1437	65	6	were	be	AUX
admet-1437	65	7	constant	constant	ADJ
admet-1437	65	8	throughout	throughout	ADP
admet-1437	65	9	the	the	DET
admet-1437	65	10	experiments	experiment	NOUN
admet-1437	65	11	,	,	PUNCT
admet-1437	65	12	with	with	ADP
admet-1437	65	13	concentrations	concentration	NOUN
admet-1437	65	14	of	of	ADP
admet-1437	65	15	25	25	NUM
admet-1437	65	16	%	%	NOUN
admet-1437	65	17	w	w	NOUN
admet-1437	65	18	drug	drug	NOUN
admet-1437	65	19	,	,	PUNCT
admet-1437	65	20	4	4	NUM
admet-1437	65	21	%	%	NOUN
admet-1437	65	22	w	w	PROPN
admet-1437	65	23	stabilizers	stabilizer	NOUN
admet-1437	65	24	and	and	CCONJ
admet-1437	65	25	71	71	NUM
admet-1437	65	26	%	%	NOUN
admet-1437	65	27	w	w	ADP
admet-1437	65	28	purified	purify	VERB
admet-1437	65	29	water	water	NOUN
admet-1437	65	30	.	.	PUNCT
admet-1437	66	1	nanocrystals	nanocrystal	NOUN
admet-1437	66	2	with	with	ADP
admet-1437	66	3	a	a	DET
admet-1437	66	4	target	target	NOUN
admet-1437	66	5	particle	particle	NOUN
admet-1437	66	6	size	size	NOUN
admet-1437	66	7	>	>	SYM
admet-1437	66	8	100	100	NUM
admet-1437	66	9	nm	nm	NOUN
admet-1437	66	10	were	be	AUX
admet-1437	66	11	manufactured	manufacture	VERB
admet-1437	66	12	with	with	ADP
admet-1437	66	13	the	the	DET
admet-1437	66	14	wet	wet	ADJ
admet-1437	66	15	media	medium	NOUN
admet-1437	66	16	mill	mill	NOUN
admet-1437	66	17	labstar	labstar	PROPN
admet-1437	66	18	,	,	PUNCT
admet-1437	66	19	netzsch	netzsch	PROPN
admet-1437	66	20	feinmahltechnik	feinmahltechnik	VERB
admet-1437	66	21	using	use	VERB
admet-1437	66	22	grinding	grind	VERB
admet-1437	66	23	media	medium	NOUN
admet-1437	66	24	made	make	VERB
admet-1437	66	25	from	from	ADP
admet-1437	66	26	yttrium	yttrium	NOUN
admet-1437	66	27	stabilized	stabilize	VERB
admet-1437	66	28	zirconia	zirconia	NOUN
admet-1437	66	29	with	with	ADP
admet-1437	66	30	a	a	DET
admet-1437	66	31	diameter	diameter	NOUN
admet-1437	66	32	of	of	ADP
admet-1437	66	33	100	100	NUM
admet-1437	66	34	or	or	CCONJ
admet-1437	66	35	300	300	NUM
admet-1437	66	36	μm	μm	NUM
admet-1437	66	37	.	.	PUNCT
admet-1437	67	1	nanocrystals	nanocrystal	NOUN
admet-1437	67	2	with	with	ADP
admet-1437	67	3	a	a	DET
admet-1437	67	4	target	target	NOUN
admet-1437	67	5	particle	particle	NOUN
admet-1437	67	6	size	size	NOUN
admet-1437	67	7	<	<	X
admet-1437	67	8	100	100	NUM
admet-1437	67	9	nm	nm	NOUN
admet-1437	67	10	were	be	AUX
admet-1437	67	11	manufactured	manufacture	VERB
admet-1437	67	12	with	with	ADP
admet-1437	67	13	the	the	DET
admet-1437	67	14	wet	wet	ADJ
admet-1437	67	15	media	media	NOUN
admet-1437	67	16	mill	mill	NOUN
admet-1437	67	17	ultra	ultra	PROPN
admet-1437	67	18	apex	apex	PROPN
admet-1437	67	19	mill	mill	NOUN
admet-1437	67	20	015	015	PROPN
admet-1437	67	21	,	,	PUNCT
admet-1437	67	22	hiroshima	hiroshima	PROPN
admet-1437	67	23	metal	metal	PROPN
admet-1437	67	24	&	&	CCONJ
admet-1437	67	25	machinery	machinery	NOUN
admet-1437	67	26	,	,	PUNCT
admet-1437	67	27	using	use	VERB
admet-1437	67	28	grinding	grind	VERB
admet-1437	67	29	media	medium	NOUN
admet-1437	67	30	made	make	VERB
admet-1437	67	31	from	from	ADP
admet-1437	67	32	yttrium	yttrium	NOUN
admet-1437	67	33	stabilized	stabilize	VERB
admet-1437	67	34	zirconia	zirconia	NOUN
admet-1437	67	35	with	with	ADP
admet-1437	67	36	a	a	DET
admet-1437	67	37	diameter	diameter	NOUN
admet-1437	67	38	of	of	ADP
admet-1437	67	39	30	30	NUM
admet-1437	67	40	μm	μm	NOUN
admet-1437	67	41	.	.	PUNCT
admet-1437	68	1	the	the	DET
admet-1437	68	2	milling	milling	NOUN
admet-1437	68	3	operations	operation	NOUN
admet-1437	68	4	were	be	AUX
admet-1437	68	5	performed	perform	VERB
admet-1437	68	6	with	with	ADP
admet-1437	68	7	a	a	DET
admet-1437	68	8	rotor	rotor	NOUN
admet-1437	68	9	tip	tip	NOUN
admet-1437	68	10	speed	speed	NOUN
admet-1437	68	11	of	of	ADP
admet-1437	68	12	12	12	NUM
admet-1437	68	13	or	or	CCONJ
admet-1437	68	14	14	14	NUM
admet-1437	68	15	m	m	NOUN
admet-1437	68	16	/	/	SYM
admet-1437	68	17	s	s	PROPN
admet-1437	68	18	and	and	CCONJ
admet-1437	68	19	a	a	DET
admet-1437	68	20	duration	duration	NOUN
admet-1437	68	21	of	of	ADP
admet-1437	68	22	up	up	ADP
admet-1437	68	23	to	to	PART
admet-1437	68	24	8	8	NUM
admet-1437	68	25	hours	hour	NOUN
admet-1437	68	26	.	.	PUNCT
admet-1437	69	1	the	the	DET
admet-1437	69	2	manufacturing	manufacturing	NOUN
admet-1437	69	3	of	of	ADP
admet-1437	69	4	the	the	DET
admet-1437	69	5	nanocrystals	nanocrystal	NOUN
admet-1437	69	6	was	be	AUX
admet-1437	69	7	controlled	control	VERB
admet-1437	69	8	by	by	ADP
admet-1437	69	9	an	an	DET
admet-1437	69	10	appropriate	appropriate	ADJ
admet-1437	69	11	cooling	cool	VERB
admet-1437	69	12	installation	installation	NOUN
admet-1437	69	13	to	to	PART
admet-1437	69	14	ensure	ensure	VERB
admet-1437	69	15	maximum	maximum	ADJ
admet-1437	69	16	temperatures	temperature	NOUN
admet-1437	69	17	of	of	ADP
admet-1437	69	18	the	the	DET
admet-1437	69	19	suspension	suspension	NOUN
admet-1437	69	20	between	between	ADP
admet-1437	69	21	20	20	NUM
admet-1437	69	22	to	to	PART
admet-1437	69	23	25	25	NUM
admet-1437	69	24	°	°	NOUN
admet-1437	69	25	c	c	NOUN
admet-1437	69	26	.	.	PUNCT
admet-1437	70	1	the	the	DET
admet-1437	70	2	surface	surface	NOUN
admet-1437	70	3	energy	energy	NOUN
admet-1437	70	4	of	of	ADP
admet-1437	70	5	the	the	DET
admet-1437	70	6	drug	drug	NOUN
admet-1437	70	7	compound	compound	NOUN
admet-1437	70	8	was	be	AUX
admet-1437	70	9	characterized	characterize	VERB
admet-1437	70	10	by	by	ADP
admet-1437	70	11	drop	drop	NOUN
admet-1437	70	12	shape	shape	NOUN
admet-1437	70	13	analysis	analysis	NOUN
admet-1437	70	14	of	of	ADP
admet-1437	70	15	the	the	DET
admet-1437	70	16	static	static	ADJ
admet-1437	70	17	contact	contact	NOUN
admet-1437	70	18	angle	angle	NOUN
admet-1437	70	19	using	use	VERB
admet-1437	70	20	the	the	DET
admet-1437	70	21	drop	drop	NOUN
admet-1437	70	22	shape	shape	NOUN
admet-1437	70	23	analyzer	analyzer	NOUN
admet-1437	70	24	dsa100	dsa100	PROPN
admet-1437	70	25	,	,	PUNCT
admet-1437	70	26	krüss	krüss	NOUN
admet-1437	70	27	,	,	PUNCT
admet-1437	70	28	and	and	CCONJ
admet-1437	70	29	as	as	ADP
admet-1437	70	30	complementary	complementary	ADJ
admet-1437	70	31	technique	technique	NOUN
admet-1437	70	32	inverse	inverse	NOUN
admet-1437	70	33	gas	gas	NOUN
admet-1437	70	34	chromatography	chromatography	NOUN
admet-1437	70	35	,	,	PUNCT
admet-1437	70	36	using	use	VERB
admet-1437	70	37	the	the	DET
admet-1437	70	38	modular	modular	ADJ
admet-1437	70	39	equipment	equipment	NOUN
admet-1437	70	40	neuronic	neuronic	ADJ
admet-1437	70	41	,	,	PUNCT
admet-1437	70	42	adscientis	adscientis	PROPN
admet-1437	70	43	,	,	PUNCT
admet-1437	70	44	which	which	PRON
admet-1437	70	45	includes	include	VERB
admet-1437	70	46	the	the	DET
admet-1437	70	47	gas	gas	NOUN
admet-1437	70	48	chromatograph	chromatograph	NOUN
admet-1437	70	49	clarus	clarus	NOUN
admet-1437	70	50	580	580	NUM
admet-1437	70	51	,	,	PUNCT
admet-1437	70	52	perkinelmer	perkinelmer	NOUN
admet-1437	70	53	.	.	PUNCT
admet-1437	71	1	surface	surface	NOUN
admet-1437	71	2	energy	energy	NOUN
admet-1437	71	3	by	by	ADP
admet-1437	71	4	drop	drop	NOUN
admet-1437	71	5	shape	shape	NOUN
admet-1437	71	6	analysis	analysis	NOUN
admet-1437	71	7	was	be	AUX
admet-1437	71	8	performed	perform	VERB
admet-1437	71	9	with	with	ADP
admet-1437	71	10	diiodomethane	diiodomethane	NOUN
admet-1437	71	11	and	and	CCONJ
admet-1437	71	12	water	water	NOUN
admet-1437	71	13	to	to	PART
admet-1437	71	14	characterize	characterize	VERB
admet-1437	71	15	the	the	DET
admet-1437	71	16	polar	polar	ADJ
admet-1437	71	17	and	and	CCONJ
admet-1437	71	18	disperse	disperse	VERB
admet-1437	71	19	part	part	NOUN
admet-1437	71	20	of	of	ADP
admet-1437	71	21	the	the	DET
admet-1437	71	22	surface	surface	NOUN
admet-1437	71	23	energy	energy	NOUN
admet-1437	71	24	using	use	VERB
admet-1437	71	25	the	the	DET
admet-1437	71	26	owens	owens	PROPN
admet-1437	71	27	-	-	PUNCT
admet-1437	71	28	wendt	wendt	NOUN
admet-1437	71	29	-	-	PUNCT
admet-1437	71	30	rabelkaelble	rabelkaelble	ADJ
admet-1437	71	31	(	(	PUNCT
admet-1437	71	32	owrk	owrk	NOUN
admet-1437	71	33	)	)	PUNCT
admet-1437	71	34	method	method	NOUN
admet-1437	71	35	for	for	ADP
admet-1437	71	36	data	data	NOUN
admet-1437	71	37	evaluation	evaluation	NOUN
admet-1437	72	1	[	[	X
admet-1437	72	2	56,57	56,57	NOUN
admet-1437	72	3	]	]	PUNCT
admet-1437	72	4	.	.	PUNCT
admet-1437	73	1	surface	surface	NOUN
admet-1437	73	2	energy	energy	NOUN
admet-1437	73	3	by	by	ADP
admet-1437	73	4	inverse	inverse	NOUN
admet-1437	73	5	gas	gas	NOUN
admet-1437	73	6	chromatography	chromatography	NOUN
admet-1437	73	7	was	be	AUX
admet-1437	73	8	performed	perform	VERB
admet-1437	73	9	at	at	ADP
admet-1437	73	10	infinite	infinite	ADJ
admet-1437	73	11	dilution	dilution	NOUN
admet-1437	73	12	with	with	ADP
admet-1437	73	13	15	15	NUM
admet-1437	73	14	gas	gas	NOUN
admet-1437	73	15	probes	probe	NOUN
admet-1437	73	16	,	,	PUNCT
admet-1437	73	17	including	include	VERB
admet-1437	73	18	n	n	CCONJ
admet-1437	73	19	-	-	PUNCT
admet-1437	73	20	alkanes	alkane	NOUN
admet-1437	73	21	,	,	PUNCT
admet-1437	73	22	cyclic	cyclic	ADJ
admet-1437	73	23	and	and	CCONJ
admet-1437	73	24	branched	branched	ADJ
admet-1437	73	25	alkanes	alkane	NOUN
admet-1437	73	26	and	and	CCONJ
admet-1437	73	27	polar	polar	ADJ
admet-1437	73	28	gases	gas	NOUN
admet-1437	73	29	,	,	PUNCT
admet-1437	73	30	to	to	PART
admet-1437	73	31	characterize	characterize	VERB
admet-1437	73	32	the	the	DET
admet-1437	73	33	disperse	disperse	ADJ
admet-1437	73	34	part	part	NOUN
admet-1437	73	35	of	of	ADP
admet-1437	73	36	the	the	DET
admet-1437	73	37	surface	surface	NOUN
admet-1437	73	38	energy	energy	NOUN
admet-1437	73	39	using	use	VERB
admet-1437	73	40	the	the	DET
admet-1437	73	41	dorris	dorris	PROPN
admet-1437	73	42	-	-	PUNCT
admet-1437	73	43	gray	gray	ADJ
admet-1437	73	44	method	method	NOUN
admet-1437	73	45	for	for	ADP
admet-1437	73	46	data	data	NOUN
admet-1437	73	47	evaluation	evaluation	NOUN
admet-1437	74	1	[	[	X
admet-1437	74	2	58	58	NUM
admet-1437	74	3	]	]	PUNCT
admet-1437	74	4	.	.	PUNCT
admet-1437	75	1	particle	particle	NOUN
admet-1437	75	2	size	size	NOUN
admet-1437	75	3	was	be	AUX
admet-1437	75	4	characterized	characterize	VERB
admet-1437	75	5	for	for	ADP
admet-1437	75	6	the	the	DET
admet-1437	75	7	coarse	coarse	PROPN
admet-1437	75	8	crystal	crystal	NOUN
admet-1437	75	9	suspension	suspension	NOUN
admet-1437	75	10	by	by	ADP
admet-1437	75	11	laser	laser	NOUN
admet-1437	75	12	light	light	ADJ
admet-1437	75	13	diffraction	diffraction	NOUN
admet-1437	75	14	(	(	PUNCT
admet-1437	75	15	lld	lld	PROPN
admet-1437	75	16	)	)	PUNCT
admet-1437	75	17	and	and	CCONJ
admet-1437	75	18	for	for	ADP
admet-1437	75	19	wet	wet	ADJ
admet-1437	75	20	media	medium	NOUN
admet-1437	75	21	milled	mill	VERB
admet-1437	75	22	nanocrystal	nanocrystal	ADJ
admet-1437	75	23	suspension	suspension	NOUN
admet-1437	75	24	samples	sample	NOUN
admet-1437	75	25	by	by	ADP
admet-1437	75	26	photon	photon	NOUN
admet-1437	75	27	correlation	correlation	NOUN
admet-1437	75	28	spectroscopy	spectroscopy	NOUN
admet-1437	75	29	(	(	PUNCT
admet-1437	75	30	pcs	pc	NOUN
admet-1437	75	31	)	)	PUNCT
admet-1437	75	32	.	.	PUNCT
admet-1437	76	1	lld	lld	PROPN
admet-1437	76	2	analysis	analysis	NOUN
admet-1437	76	3	was	be	AUX
admet-1437	76	4	performed	perform	VERB
admet-1437	76	5	using	use	VERB
admet-1437	76	6	the	the	DET
admet-1437	76	7	equipment	equipment	NOUN
admet-1437	76	8	model	model	NOUN
admet-1437	76	9	sucell	sucell	NOUN
admet-1437	76	10	/	/	SYM
admet-1437	76	11	helos	helo	NOUN
admet-1437	76	12	,	,	PUNCT
admet-1437	76	13	sympatec	sympatec	NOUN
admet-1437	76	14	with	with	ADP
admet-1437	76	15	the	the	DET
admet-1437	76	16	measuring	measure	VERB
admet-1437	76	17	range	range	NOUN
admet-1437	76	18	r2	r2	NOUN
admet-1437	76	19	by	by	ADP
admet-1437	76	20	dispersing	disperse	VERB
admet-1437	76	21	the	the	DET
admet-1437	76	22	powder	powder	NOUN
admet-1437	76	23	in	in	ADP
admet-1437	76	24	purified	purified	ADJ
admet-1437	76	25	water	water	NOUN
admet-1437	76	26	with	with	ADP
admet-1437	76	27	minute	minute	ADJ
admet-1437	76	28	amounts	amount	NOUN
admet-1437	76	29	of	of	ADP
admet-1437	76	30	the	the	DET
admet-1437	76	31	dispersing	disperse	VERB
admet-1437	76	32	aid	aid	NOUN
admet-1437	76	33	(	(	PUNCT
admet-1437	76	34	10	10	NUM
admet-1437	76	35	%	%	NOUN
admet-1437	76	36	w	w	NOUN
admet-1437	76	37	tween	tween	NOUN
admet-1437	76	38	20	20	NUM
admet-1437	76	39	)	)	PUNCT
admet-1437	76	40	and	and	CCONJ
admet-1437	76	41	sonication	sonication	NOUN
admet-1437	76	42	of	of	ADP
admet-1437	76	43	the	the	DET
admet-1437	76	44	test	test	NOUN
admet-1437	76	45	dispersion	dispersion	NOUN
admet-1437	76	46	until	until	SCONJ
admet-1437	76	47	the	the	DET
admet-1437	76	48	primary	primary	ADJ
admet-1437	76	49	particle	particle	NOUN
admet-1437	76	50	size	size	NOUN
admet-1437	76	51	distribution	distribution	NOUN
admet-1437	76	52	was	be	AUX
admet-1437	76	53	reached	reach	VERB
admet-1437	76	54	.	.	PUNCT
admet-1437	77	1	the	the	DET
admet-1437	77	2	obtained	obtain	VERB
admet-1437	77	3	angular	angular	ADJ
admet-1437	77	4	scattered	scatter	VERB
admet-1437	77	5	light	light	NOUN
admet-1437	77	6	was	be	AUX
admet-1437	77	7	evaluated	evaluate	VERB
admet-1437	77	8	according	accord	VERB
admet-1437	77	9	to	to	ADP
admet-1437	77	10	fraunhofer	fraunhofer	PROPN
admet-1437	77	11	light	light	ADJ
admet-1437	77	12	diffraction	diffraction	NOUN
admet-1437	77	13	theory	theory	NOUN
admet-1437	77	14	and	and	CCONJ
admet-1437	77	15	results	result	NOUN
admet-1437	77	16	were	be	AUX
admet-1437	77	17	reported	report	VERB
admet-1437	77	18	by	by	ADP
admet-1437	77	19	volumebased	volumebased	ADJ
admet-1437	77	20	(	(	PUNCT
admet-1437	77	21	q3	q3	NOUN
admet-1437	77	22	)	)	PUNCT
admet-1437	77	23	particle	particle	NOUN
admet-1437	77	24	size	size	NOUN
admet-1437	77	25	distribution	distribution	NOUN
admet-1437	77	26	[	[	X
admet-1437	77	27	59	59	NUM
admet-1437	77	28	]	]	PUNCT
admet-1437	77	29	.	.	PUNCT
admet-1437	78	1	pcs	pc	NOUN
admet-1437	78	2	analysis	analysis	NOUN
admet-1437	78	3	was	be	AUX
admet-1437	78	4	performed	perform	VERB
admet-1437	78	5	using	use	VERB
admet-1437	78	6	the	the	DET
admet-1437	78	7	equipment	equipment	NOUN
admet-1437	78	8	model	model	NOUN
admet-1437	78	9	zetasizer	zetasizer	PROPN
admet-1437	78	10	nano	nano	PROPN
admet-1437	78	11	zs	zs	PROPN
admet-1437	78	12	,	,	PUNCT
admet-1437	78	13	malvern	malvern	PROPN
admet-1437	78	14	instruments	instrument	NOUN
admet-1437	78	15	,	,	PUNCT
admet-1437	78	16	by	by	ADP
admet-1437	78	17	dilution	dilution	NOUN
admet-1437	78	18	of	of	ADP
admet-1437	78	19	the	the	DET
admet-1437	78	20	nanocrystal	nanocrystal	ADJ
admet-1437	78	21	suspension	suspension	NOUN
admet-1437	78	22	in	in	ADP
admet-1437	78	23	sterile	sterile	ADJ
admet-1437	78	24	filtered	filter	VERB
admet-1437	78	25	0.1	0.1	NUM
admet-1437	78	26	mm	mm	PROPN
admet-1437	78	27	nacl	nacl	ADJ
admet-1437	78	28	aqueous	aqueous	ADJ
admet-1437	78	29	solution	solution	NOUN
admet-1437	78	30	.	.	PUNCT
admet-1437	79	1	the	the	DET
admet-1437	79	2	obtained	obtain	VERB
admet-1437	79	3	scattered	scatter	VERB
admet-1437	79	4	light	light	ADJ
admet-1437	79	5	intensity	intensity	NOUN
admet-1437	79	6	dynamics	dynamic	NOUN
admet-1437	79	7	was	be	AUX
admet-1437	79	8	evaluated	evaluate	VERB
admet-1437	79	9	according	accord	VERB
admet-1437	79	10	to	to	ADP
admet-1437	79	11	the	the	DET
admet-1437	79	12	cumulant	cumulant	ADJ
admet-1437	79	13	method	method	NOUN
admet-1437	79	14	and	and	CCONJ
admet-1437	79	15	results	result	NOUN
admet-1437	79	16	were	be	AUX
admet-1437	79	17	reported	report	VERB
admet-1437	79	18	by	by	ADP
admet-1437	79	19	scattering	scatter	VERB
admet-1437	79	20	intensity	intensity	NOUN
admet-1437	79	21	weighted	weight	VERB
admet-1437	79	22	mean	mean	ADJ
admet-1437	79	23	particle	particle	NOUN
admet-1437	79	24	size	size	NOUN
admet-1437	79	25	and	and	CCONJ
admet-1437	79	26	polydispersity	polydispersity	NOUN
admet-1437	79	27	index	index	NOUN
admet-1437	79	28	as	as	ADP
admet-1437	79	29	a	a	DET
admet-1437	79	30	measure	measure	NOUN
admet-1437	79	31	of	of	ADP
admet-1437	79	32	the	the	DET
admet-1437	79	33	width	width	NOUN
admet-1437	79	34	of	of	ADP
admet-1437	79	35	the	the	DET
admet-1437	79	36	particle	particle	NOUN
admet-1437	79	37	size	size	NOUN
admet-1437	79	38	distribution	distribution	NOUN
admet-1437	79	39	[	[	X
admet-1437	79	40	60	60	NUM
admet-1437	79	41	]	]	PUNCT
admet-1437	79	42	.	.	PUNCT
admet-1437	80	1	further	far	ADV
admet-1437	80	2	,	,	PUNCT
admet-1437	80	3	the	the	DET
admet-1437	80	4	refractive	refractive	ADJ
admet-1437	80	5	index	index	NOUN
admet-1437	80	6	of	of	ADP
admet-1437	80	7	the	the	DET
admet-1437	80	8	drug	drug	NOUN
admet-1437	80	9	compound	compound	NOUN
admet-1437	80	10	was	be	AUX
admet-1437	80	11	determined	determine	VERB
admet-1437	80	12	according	accord	VERB
admet-1437	80	13	to	to	ADP
admet-1437	80	14	the	the	DET
admet-1437	80	15	becke	becke	NOUN
admet-1437	80	16	line	line	NOUN
admet-1437	80	17	phenomenon	phenomenon	NOUN
admet-1437	80	18	[	[	X
admet-1437	80	19	61	61	NUM
admet-1437	80	20	]	]	PUNCT
admet-1437	80	21	.	.	PUNCT
admet-1437	81	1	the	the	DET
admet-1437	81	2	determined	determine	VERB
admet-1437	81	3	refractive	refractive	ADJ
admet-1437	81	4	index	index	NOUN
admet-1437	81	5	was	be	AUX
admet-1437	81	6	used	use	VERB
admet-1437	81	7	as	as	ADP
admet-1437	81	8	an	an	DET
admet-1437	81	9	input	input	NOUN
admet-1437	81	10	parameter	parameter	NOUN
admet-1437	81	11	to	to	PART
admet-1437	81	12	calculate	calculate	VERB
admet-1437	81	13	the	the	DET
admet-1437	81	14	volume	volume	NOUN
admet-1437	81	15	-	-	PUNCT
admet-1437	81	16	based	base	VERB
admet-1437	81	17	(	(	PUNCT
admet-1437	81	18	q3	q3	NOUN
admet-1437	81	19	)	)	PUNCT
admet-1437	81	20	particle	particle	NOUN
admet-1437	81	21	size	size	NOUN
admet-1437	81	22	distribution	distribution	NOUN
admet-1437	81	23	from	from	ADP
admet-1437	81	24	the	the	DET
admet-1437	81	25	scattering	scatter	VERB
admet-1437	81	26	intensity	intensity	NOUN
admet-1437	81	27	weighted	weight	VERB
admet-1437	81	28	mean	mean	ADJ
admet-1437	81	29	particle	particle	NOUN
admet-1437	81	30	size	size	NOUN
admet-1437	81	31	and	and	CCONJ
admet-1437	81	32	polydispersity	polydispersity	NOUN
admet-1437	81	33	index	index	NOUN
admet-1437	81	34	of	of	ADP
admet-1437	81	35	the	the	DET
admet-1437	81	36	pcs	pc	NOUN
admet-1437	81	37	analysis	analysis	NOUN
admet-1437	81	38	using	use	VERB
admet-1437	81	39	the	the	DET
admet-1437	81	40	builtin	builtin	PROPN
admet-1437	81	41	instrument	instrument	NOUN
admet-1437	81	42	software	software	NOUN
admet-1437	81	43	.	.	PUNCT
admet-1437	82	1	as	as	ADP
admet-1437	82	2	a	a	DET
admet-1437	82	3	complementary	complementary	ADJ
admet-1437	82	4	analysis	analysis	NOUN
admet-1437	82	5	,	,	PUNCT
admet-1437	82	6	particle	particle	NOUN
admet-1437	82	7	size	size	NOUN
admet-1437	82	8	and	and	CCONJ
admet-1437	82	9	morphology	morphology	NOUN
admet-1437	82	10	of	of	ADP
admet-1437	82	11	nanocrystals	nanocrystal	NOUN
admet-1437	82	12	were	be	AUX
admet-1437	82	13	characterized	characterize	VERB
admet-1437	82	14	by	by	ADP
admet-1437	82	15	scanning	scan	VERB
admet-1437	82	16	electron	electron	NOUN
admet-1437	82	17	microscopy	microscopy	NOUN
admet-1437	82	18	(	(	PUNCT
admet-1437	82	19	sem	sem	NOUN
admet-1437	82	20	)	)	PUNCT
admet-1437	82	21	using	use	VERB
admet-1437	82	22	the	the	DET
admet-1437	82	23	equipment	equipment	NOUN
admet-1437	82	24	model	model	NOUN
admet-1437	82	25	geminisem	geminisem	NOUN
admet-1437	82	26	300	300	NUM
admet-1437	82	27	,	,	PUNCT
admet-1437	82	28	carl	carl	PROPN
admet-1437	82	29	zeiss	zeiss	PROPN
admet-1437	82	30	microscopy	microscopy	PROPN
admet-1437	82	31	.	.	PUNCT
admet-1437	83	1	all	all	DET
admet-1437	83	2	images	image	NOUN
admet-1437	83	3	were	be	AUX
admet-1437	83	4	obtained	obtain	VERB
admet-1437	83	5	using	use	VERB
admet-1437	83	6	an	an	DET
admet-1437	83	7	accelerating	accelerate	VERB
admet-1437	83	8	voltage	voltage	NOUN
admet-1437	83	9	of	of	ADP
admet-1437	83	10	5	5	NUM
admet-1437	83	11	kv	kv	PROPN
admet-1437	83	12	.	.	PUNCT
admet-1437	84	1	sample	sample	NOUN
admet-1437	84	2	preparation	preparation	NOUN
admet-1437	84	3	was	be	AUX
admet-1437	84	4	performed	perform	VERB
admet-1437	84	5	by	by	ADP
admet-1437	84	6	filtration	filtration	NOUN
admet-1437	84	7	of	of	ADP
admet-1437	84	8	the	the	DET
admet-1437	84	9	nanocrystal	nanocrystal	ADJ
admet-1437	84	10	suspension	suspension	NOUN
admet-1437	84	11	through	through	ADP
admet-1437	84	12	a	a	DET
admet-1437	84	13	nucleopore	nucleopore	ADJ
admet-1437	84	14	membrane	membrane	NOUN
admet-1437	84	15	filter	filter	NOUN
admet-1437	84	16	and	and	CCONJ
admet-1437	84	17	sputtercoated	sputtercoate	VERB
admet-1437	84	18	with	with	ADP
admet-1437	84	19	gold	gold	NOUN
admet-1437	84	20	.	.	PUNCT
admet-1437	85	1	the	the	DET
admet-1437	85	2	saturation	saturation	NOUN
admet-1437	85	3	solubility	solubility	NOUN
admet-1437	85	4	of	of	ADP
admet-1437	85	5	nanocrystals	nanocrystal	NOUN
admet-1437	85	6	was	be	AUX
admet-1437	85	7	determined	determine	VERB
admet-1437	85	8	by	by	ADP
admet-1437	85	9	the	the	DET
admet-1437	85	10	addition	addition	NOUN
admet-1437	85	11	of	of	ADP
admet-1437	85	12	the	the	DET
admet-1437	85	13	required	require	VERB
admet-1437	85	14	amount	amount	NOUN
admet-1437	85	15	of	of	ADP
admet-1437	85	16	nanocrystal	nanocrystal	ADJ
admet-1437	85	17	suspension	suspension	NOUN
admet-1437	85	18	with	with	ADP
admet-1437	85	19	known	know	VERB
admet-1437	85	20	assay	assay	NOUN
admet-1437	85	21	into	into	ADP
admet-1437	85	22	1	1	NUM
admet-1437	85	23	l	l	NOUN
admet-1437	85	24	of	of	ADP
admet-1437	85	25	either	either	DET
admet-1437	85	26	0.01	0.01	NUM
admet-1437	85	27	m	m	PROPN
admet-1437	85	28	hydrochloric	hydrochloric	ADJ
admet-1437	85	29	acid	acid	NOUN
admet-1437	85	30	ph	ph	VERB
admet-1437	85	31	2	2	NUM
admet-1437	85	32	solution	solution	NOUN
admet-1437	85	33	,	,	PUNCT
admet-1437	85	34	ph	ph	ADJ
admet-1437	85	35	3	3	NUM
admet-1437	85	36	citrate	citrate	NOUN
admet-1437	85	37	buffer	buffer	NOUN
admet-1437	85	38	or	or	CCONJ
admet-1437	85	39	ph	ph	VERB
admet-1437	85	40	4.5	4.5	NUM
admet-1437	85	41	sodium	sodium	NOUN
admet-1437	85	42	acetate	acetate	NOUN
admet-1437	85	43	buffer	buffer	NOUN
admet-1437	85	44	.	.	PUNCT
admet-1437	86	1	the	the	DET
admet-1437	86	2	suspensions	suspension	NOUN
admet-1437	86	3	were	be	AUX
admet-1437	86	4	equilibrated	equilibrate	VERB
admet-1437	86	5	at	at	ADP
admet-1437	86	6	22	22	NUM
admet-1437	86	7	°	°	ADP
admet-1437	86	8	c	c	NOUN
admet-1437	86	9	for	for	ADP
admet-1437	86	10	24	24	NUM
admet-1437	86	11	h	h	NOUN
admet-1437	86	12	under	under	ADP
admet-1437	86	13	continuous	continuous	ADJ
admet-1437	86	14	stirring	stirring	NOUN
admet-1437	86	15	using	use	VERB
admet-1437	86	16	appropriate	appropriate	ADJ
admet-1437	86	17	magnetic	magnetic	ADJ
admet-1437	86	18	stirrers	stirrer	NOUN
admet-1437	86	19	to	to	PART
admet-1437	86	20	ensure	ensure	VERB
admet-1437	86	21	a	a	DET
admet-1437	86	22	constant	constant	ADJ
admet-1437	86	23	suspension	suspension	NOUN
admet-1437	86	24	temperature	temperature	NOUN
admet-1437	86	25	throughout	throughout	ADP
admet-1437	86	26	the	the	DET
admet-1437	86	27	equilibration	equilibration	NOUN
admet-1437	86	28	time	time	NOUN
admet-1437	86	29	.	.	PUNCT
admet-1437	87	1	three	three	NUM
admet-1437	87	2	aliquots	aliquot	NOUN
admet-1437	87	3	were	be	AUX
admet-1437	87	4	taken	take	VERB
admet-1437	87	5	from	from	ADP
admet-1437	87	6	the	the	DET
admet-1437	87	7	equilibrated	equilibrate	VERB
admet-1437	87	8	suspension	suspension	NOUN
admet-1437	87	9	using	use	VERB
admet-1437	87	10	an	an	DET
admet-1437	87	11	admet	admet	NOUN
admet-1437	87	12	&	&	CCONJ
admet-1437	87	13	dmpk	dmpk	PROPN
admet-1437	87	14	10(4	10(4	NUM
admet-1437	87	15	)	)	PUNCT
admet-1437	87	16	(	(	PUNCT
admet-1437	87	17	2022	2022	NUM
admet-1437	87	18	)	)	PUNCT
admet-1437	87	19	253	253	NUM
admet-1437	87	20	-	-	SYM
admet-1437	87	21	287	287	NUM
admet-1437	87	22	modeling	modeling	NOUN
admet-1437	87	23	of	of	ADP
admet-1437	87	24	drug	drug	NOUN
admet-1437	87	25	nanocrystals	nanocrystal	NOUN
admet-1437	87	26	dissolution	dissolution	NOUN
admet-1437	87	27	doi	doi	PROPN
admet-1437	87	28	:	:	PUNCT
admet-1437	87	29	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	87	30	257	257	NUM
admet-1437	87	31	electronic	electronic	ADJ
admet-1437	87	32	pipette	pipette	NOUN
admet-1437	87	33	,	,	PUNCT
admet-1437	87	34	where	where	SCONJ
admet-1437	87	35	one	one	NUM
admet-1437	87	36	aliquot	aliquot	NOUN
admet-1437	87	37	was	be	AUX
admet-1437	87	38	used	use	VERB
admet-1437	87	39	to	to	PART
admet-1437	87	40	confirm	confirm	VERB
admet-1437	87	41	the	the	DET
admet-1437	87	42	temperature	temperature	NOUN
admet-1437	87	43	and	and	CCONJ
admet-1437	87	44	the	the	DET
admet-1437	87	45	ph	ph	NOUN
admet-1437	87	46	of	of	ADP
admet-1437	87	47	the	the	DET
admet-1437	87	48	related	relate	VERB
admet-1437	87	49	suspension	suspension	NOUN
admet-1437	87	50	.	.	PUNCT
admet-1437	88	1	the	the	DET
admet-1437	88	2	other	other	ADJ
admet-1437	88	3	two	two	NUM
admet-1437	88	4	aliquots	aliquot	NOUN
admet-1437	88	5	were	be	AUX
admet-1437	88	6	transferred	transfer	VERB
admet-1437	88	7	into	into	ADP
admet-1437	88	8	thick	thick	ADJ
admet-1437	88	9	-	-	PUNCT
admet-1437	88	10	wall	wall	NOUN
admet-1437	88	11	polycarbonate	polycarbonate	NOUN
admet-1437	88	12	centrifuge	centrifuge	NOUN
admet-1437	88	13	tubes	tube	NOUN
admet-1437	88	14	and	and	CCONJ
admet-1437	88	15	inserted	insert	VERB
admet-1437	88	16	into	into	ADP
admet-1437	88	17	an	an	DET
admet-1437	88	18	ultracentrifuge	ultracentrifuge	NOUN
admet-1437	88	19	,	,	PUNCT
admet-1437	88	20	beckmann	beckmann	PROPN
admet-1437	88	21	coulter	coulter	PROPN
admet-1437	88	22	optima	optima	PROPN
admet-1437	88	23	™	™	PROPN
admet-1437	88	24	max	max	PROPN
admet-1437	88	25	-	-	PUNCT
admet-1437	88	26	xp	xp	PROPN
admet-1437	88	27	,	,	PUNCT
admet-1437	88	28	for	for	ADP
admet-1437	88	29	analysis	analysis	NOUN
admet-1437	88	30	in	in	ADP
admet-1437	88	31	duplicate	duplicate	NOUN
admet-1437	88	32	.	.	PUNCT
admet-1437	89	1	the	the	DET
admet-1437	89	2	ultracentrifuge	ultracentrifuge	NOUN
admet-1437	89	3	was	be	AUX
admet-1437	89	4	operated	operate	VERB
admet-1437	89	5	for	for	ADP
admet-1437	89	6	the	the	DET
admet-1437	89	7	first	first	ADJ
admet-1437	89	8	5	5	NUM
admet-1437	89	9	min	min	NOUN
admet-1437	89	10	until	until	ADP
admet-1437	89	11	a	a	DET
admet-1437	89	12	temperature	temperature	NOUN
admet-1437	89	13	of	of	ADP
admet-1437	89	14	22	22	NUM
admet-1437	89	15	°	°	NOUN
admet-1437	89	16	c	c	NOUN
admet-1437	89	17	and	and	CCONJ
admet-1437	89	18	the	the	DET
admet-1437	89	19	required	required	ADJ
admet-1437	89	20	vacuum	vacuum	NOUN
admet-1437	89	21	were	be	AUX
admet-1437	89	22	reached	reach	VERB
admet-1437	89	23	.	.	PUNCT
admet-1437	90	1	subsequently	subsequently	ADV
admet-1437	90	2	,	,	PUNCT
admet-1437	90	3	the	the	DET
admet-1437	90	4	sample	sample	NOUN
admet-1437	90	5	was	be	AUX
admet-1437	90	6	centrifuged	centrifuge	VERB
admet-1437	90	7	at	at	ADP
admet-1437	90	8	541’000	541’000	NUM
admet-1437	90	9	-	-	ADJ
admet-1437	90	10	fold	fold	ADJ
admet-1437	90	11	gravity	gravity	NOUN
admet-1437	90	12	for	for	ADP
admet-1437	90	13	10	10	NUM
admet-1437	90	14	min	min	NOUN
admet-1437	90	15	at	at	ADP
admet-1437	90	16	a	a	DET
admet-1437	90	17	constant	constant	ADJ
admet-1437	90	18	temperature	temperature	NOUN
admet-1437	90	19	of	of	ADP
admet-1437	90	20	22	22	NUM
admet-1437	90	21	°	°	NOUN
admet-1437	90	22	c	c	NOUN
admet-1437	90	23	.	.	PUNCT
admet-1437	91	1	an	an	DET
admet-1437	91	2	aliquot	aliquot	NOUN
admet-1437	91	3	of	of	ADP
admet-1437	91	4	the	the	DET
admet-1437	91	5	supernatant	supernatant	NOUN
admet-1437	91	6	was	be	AUX
admet-1437	91	7	collected	collect	VERB
admet-1437	91	8	from	from	ADP
admet-1437	91	9	the	the	DET
admet-1437	91	10	centrifuge	centrifuge	NOUN
admet-1437	91	11	tube	tube	NOUN
admet-1437	91	12	using	use	VERB
admet-1437	91	13	an	an	DET
admet-1437	91	14	electronic	electronic	ADJ
admet-1437	91	15	pipette	pipette	NOUN
admet-1437	91	16	after	after	ADP
admet-1437	91	17	completion	completion	NOUN
admet-1437	91	18	of	of	ADP
admet-1437	91	19	the	the	DET
admet-1437	91	20	ultracentrifugation	ultracentrifugation	NOUN
admet-1437	91	21	.	.	PUNCT
admet-1437	92	1	the	the	DET
admet-1437	92	2	absence	absence	NOUN
admet-1437	92	3	of	of	ADP
admet-1437	92	4	particulate	particulate	NOUN
admet-1437	92	5	matter	matter	NOUN
admet-1437	92	6	in	in	ADP
admet-1437	92	7	this	this	DET
admet-1437	92	8	aliquot	aliquot	NOUN
admet-1437	92	9	was	be	AUX
admet-1437	92	10	confirmed	confirm	VERB
admet-1437	92	11	for	for	ADP
admet-1437	92	12	the	the	DET
admet-1437	92	13	finest	fine	ADJ
admet-1437	92	14	nanocrystals	nanocrystal	NOUN
admet-1437	92	15	by	by	ADP
admet-1437	92	16	photon	photon	NOUN
admet-1437	92	17	correlation	correlation	NOUN
admet-1437	92	18	spectroscopy	spectroscopy	NOUN
admet-1437	92	19	(	(	PUNCT
admet-1437	92	20	pcs	pc	NOUN
admet-1437	92	21	)	)	PUNCT
admet-1437	92	22	during	during	ADP
admet-1437	92	23	method	method	NOUN
admet-1437	92	24	development	development	NOUN
admet-1437	92	25	.	.	PUNCT
admet-1437	93	1	the	the	DET
admet-1437	93	2	aliquot	aliquot	NOUN
admet-1437	93	3	was	be	AUX
admet-1437	93	4	diluted	dilute	VERB
admet-1437	93	5	with	with	ADP
admet-1437	93	6	a	a	DET
admet-1437	93	7	fixed	fix	VERB
admet-1437	93	8	ratio	ratio	NOUN
admet-1437	93	9	of	of	ADP
admet-1437	93	10	an	an	DET
admet-1437	93	11	organic	organic	ADJ
admet-1437	93	12	solvent	solvent	NOUN
admet-1437	93	13	to	to	PART
admet-1437	93	14	robustly	robustly	ADV
admet-1437	93	15	rule	rule	VERB
admet-1437	93	16	out	out	ADP
admet-1437	93	17	any	any	DET
admet-1437	93	18	potential	potential	ADJ
admet-1437	93	19	precipitation	precipitation	NOUN
admet-1437	93	20	of	of	ADP
admet-1437	93	21	the	the	DET
admet-1437	93	22	solubilized	solubilize	VERB
admet-1437	93	23	drug	drug	NOUN
admet-1437	93	24	.	.	PUNCT
admet-1437	94	1	finally	finally	ADV
admet-1437	94	2	,	,	PUNCT
admet-1437	94	3	this	this	DET
admet-1437	94	4	aliquot	aliquot	NOUN
admet-1437	94	5	was	be	AUX
admet-1437	94	6	analyzed	analyze	VERB
admet-1437	94	7	for	for	ADP
admet-1437	94	8	assay	assay	NOUN
admet-1437	94	9	by	by	ADP
admet-1437	94	10	high	high	ADJ
admet-1437	94	11	pressure	pressure	NOUN
admet-1437	94	12	liquid	liquid	NOUN
admet-1437	94	13	chromatography	chromatography	NOUN
admet-1437	94	14	(	(	PUNCT
admet-1437	94	15	hplc	hplc	PROPN
admet-1437	94	16	)	)	PUNCT
admet-1437	94	17	,	,	PUNCT
admet-1437	94	18	agilent	agilent	PROPN
admet-1437	94	19	1290	1290	NUM
admet-1437	94	20	infinity	infinity	NOUN
admet-1437	94	21	lc	lc	NOUN
admet-1437	94	22	using	use	VERB
admet-1437	94	23	a	a	DET
admet-1437	94	24	validated	validate	VERB
admet-1437	94	25	method	method	NOUN
admet-1437	94	26	with	with	ADP
admet-1437	94	27	an	an	DET
admet-1437	94	28	analytical	analytical	ADJ
admet-1437	94	29	precision	precision	NOUN
admet-1437	94	30	of	of	ADP
admet-1437	94	31	better	well	ADJ
admet-1437	94	32	than	than	ADP
admet-1437	94	33	0.3	0.3	NUM
admet-1437	94	34	%	%	NOUN
admet-1437	94	35	relative	relative	ADJ
admet-1437	94	36	standard	standard	ADJ
admet-1437	94	37	deviation	deviation	NOUN
admet-1437	94	38	and	and	CCONJ
admet-1437	94	39	a	a	DET
admet-1437	94	40	simultaneously	simultaneously	ADV
admet-1437	94	41	operated	operate	VERB
admet-1437	94	42	system	system	NOUN
admet-1437	94	43	suitability	suitability	NOUN
admet-1437	94	44	test	test	NOUN
admet-1437	94	45	.	.	PUNCT
admet-1437	95	1	in	in	ADP
admet-1437	95	2	addition	addition	NOUN
admet-1437	95	3	,	,	PUNCT
admet-1437	95	4	the	the	DET
admet-1437	95	5	stability	stability	NOUN
admet-1437	95	6	of	of	ADP
admet-1437	95	7	the	the	DET
admet-1437	95	8	solubility	solubility	NOUN
admet-1437	95	9	of	of	ADP
admet-1437	95	10	nanocrystals	nanocrystal	NOUN
admet-1437	95	11	was	be	AUX
admet-1437	95	12	investigated	investigate	VERB
admet-1437	95	13	by	by	ADP
admet-1437	95	14	applying	apply	VERB
admet-1437	95	15	extended	extended	ADJ
admet-1437	95	16	equilibration	equilibration	NOUN
admet-1437	95	17	times	time	NOUN
admet-1437	95	18	using	use	VERB
admet-1437	95	19	the	the	DET
admet-1437	95	20	sample	sample	NOUN
admet-1437	95	21	preparation	preparation	NOUN
admet-1437	95	22	and	and	CCONJ
admet-1437	95	23	analytical	analytical	ADJ
admet-1437	95	24	method	method	NOUN
admet-1437	95	25	as	as	SCONJ
admet-1437	95	26	described	describe	VERB
admet-1437	95	27	above	above	ADV
admet-1437	95	28	.	.	PUNCT
admet-1437	96	1	x	x	X
admet-1437	96	2	-	-	PUNCT
admet-1437	96	3	ray	ray	NOUN
admet-1437	96	4	powder	powder	NOUN
admet-1437	96	5	diffraction	diffraction	NOUN
admet-1437	96	6	(	(	PUNCT
admet-1437	96	7	xrpd	xrpd	ADJ
admet-1437	96	8	)	)	PUNCT
admet-1437	96	9	was	be	AUX
admet-1437	96	10	performed	perform	VERB
admet-1437	96	11	using	use	VERB
admet-1437	96	12	a	a	DET
admet-1437	96	13	rigaku	rigaku	NOUN
admet-1437	96	14	,	,	PUNCT
admet-1437	96	15	smart	smart	ADJ
admet-1437	96	16	lab	lab	NOUN
admet-1437	96	17	ii	ii	NOUN
admet-1437	96	18	in	in	ADP
admet-1437	96	19	either	either	CCONJ
admet-1437	96	20	reflection	reflection	NOUN
admet-1437	96	21	or	or	CCONJ
admet-1437	96	22	transmission	transmission	NOUN
admet-1437	96	23	mode	mode	NOUN
admet-1437	96	24	.	.	PUNCT
admet-1437	97	1	for	for	ADP
admet-1437	97	2	both	both	DET
admet-1437	97	3	modes	mode	NOUN
admet-1437	97	4	,	,	PUNCT
admet-1437	97	5	an	an	DET
admet-1437	97	6	angular	angular	ADJ
admet-1437	97	7	range	range	NOUN
admet-1437	97	8	between	between	ADP
admet-1437	97	9	2	2	NUM
admet-1437	97	10	°	°	NOUN
admet-1437	97	11	to	to	ADP
admet-1437	97	12	40	40	NUM
admet-1437	97	13	°	°	NOUN
admet-1437	97	14	2θ	2θ	NUM
admet-1437	97	15	was	be	AUX
admet-1437	97	16	scanned	scan	VERB
admet-1437	97	17	with	with	ADP
admet-1437	97	18	an	an	DET
admet-1437	97	19	angular	angular	ADJ
admet-1437	97	20	step	step	NOUN
admet-1437	97	21	of	of	ADP
admet-1437	97	22	0.017	0.017	NUM
admet-1437	97	23	°	°	PROPN
admet-1437	97	24	.	.	PUNCT
admet-1437	98	1	cu	cu	PROPN
admet-1437	98	2	-	-	PUNCT
admet-1437	98	3	kα	kα	PROPN
admet-1437	98	4	radiation	radiation	NOUN
admet-1437	98	5	at	at	ADP
admet-1437	98	6	40	40	NUM
admet-1437	98	7	kv	kv	PROPN
admet-1437	98	8	and	and	CCONJ
admet-1437	98	9	40	40	NUM
admet-1437	98	10	ma	ma	NOUN
admet-1437	98	11	was	be	AUX
admet-1437	98	12	used	use	VERB
admet-1437	98	13	throughout	throughout	ADP
admet-1437	98	14	the	the	DET
admet-1437	98	15	measurements	measurement	NOUN
admet-1437	98	16	.	.	PUNCT
admet-1437	99	1	in	in	ADP
admet-1437	99	2	reflection	reflection	NOUN
admet-1437	99	3	mode	mode	NOUN
admet-1437	99	4	,	,	PUNCT
admet-1437	99	5	10.00	10.00	NUM
admet-1437	99	6	±	±	NUM
admet-1437	99	7	0.05	0.05	NUM
admet-1437	99	8	mg	mg	NOUN
admet-1437	99	9	of	of	ADP
admet-1437	99	10	powder	powder	NOUN
admet-1437	99	11	was	be	AUX
admet-1437	99	12	prepared	prepare	VERB
admet-1437	99	13	on	on	ADP
admet-1437	99	14	a	a	DET
admet-1437	99	15	low	low	ADJ
admet-1437	99	16	background	background	NOUN
admet-1437	99	17	si	si	NOUN
admet-1437	99	18	-	-	PUNCT
admet-1437	99	19	sample	sample	NOUN
admet-1437	99	20	holder	holder	NOUN
admet-1437	99	21	for	for	ADP
admet-1437	99	22	each	each	DET
admet-1437	99	23	sample	sample	NOUN
admet-1437	99	24	.	.	PUNCT
admet-1437	100	1	the	the	DET
admet-1437	100	2	sample	sample	NOUN
admet-1437	100	3	holders	holder	NOUN
admet-1437	100	4	were	be	AUX
admet-1437	100	5	spun	spin	VERB
admet-1437	100	6	at	at	ADP
admet-1437	100	7	2	2	NUM
admet-1437	100	8	hz	hz	VERB
admet-1437	100	9	during	during	ADP
admet-1437	100	10	the	the	DET
admet-1437	100	11	measurement	measurement	NOUN
admet-1437	100	12	.	.	PUNCT
admet-1437	101	1	a	a	DET
admet-1437	101	2	scan	scan	ADJ
admet-1437	101	3	speed	speed	NOUN
admet-1437	101	4	of	of	ADP
admet-1437	101	5	1.7	1.7	NUM
admet-1437	101	6	°	°	NOUN
admet-1437	101	7	/min	/min	NOUN
admet-1437	101	8	was	be	AUX
admet-1437	101	9	used	use	VERB
admet-1437	101	10	.	.	PUNCT
admet-1437	102	1	samples	sample	NOUN
admet-1437	102	2	were	be	AUX
admet-1437	102	3	measured	measure	VERB
admet-1437	102	4	in	in	ADP
admet-1437	102	5	triplicate	triplicate	NOUN
admet-1437	102	6	to	to	PART
admet-1437	102	7	obtain	obtain	VERB
admet-1437	102	8	an	an	DET
admet-1437	102	9	average	average	ADJ
admet-1437	102	10	signal	signal	NOUN
admet-1437	102	11	,	,	PUNCT
admet-1437	102	12	whereby	whereby	SCONJ
admet-1437	102	13	for	for	ADP
admet-1437	102	14	each	each	DET
admet-1437	102	15	measurement	measurement	NOUN
admet-1437	102	16	,	,	PUNCT
admet-1437	102	17	a	a	DET
admet-1437	102	18	new	new	ADJ
admet-1437	102	19	sample	sample	NOUN
admet-1437	102	20	holder	holder	NOUN
admet-1437	102	21	was	be	AUX
admet-1437	102	22	prepared	prepare	VERB
admet-1437	102	23	.	.	PUNCT
admet-1437	103	1	in	in	ADP
admet-1437	103	2	transmission	transmission	NOUN
admet-1437	103	3	mode	mode	NOUN
admet-1437	103	4	,	,	PUNCT
admet-1437	103	5	a	a	DET
admet-1437	103	6	0.7	0.7	NUM
admet-1437	103	7	mm	mm	NOUN
admet-1437	103	8	od	od	NOUN
admet-1437	103	9	glass	glass	NOUN
admet-1437	103	10	capillary	capillary	ADJ
admet-1437	103	11	with	with	ADP
admet-1437	103	12	80	80	NUM
admet-1437	103	13	to	to	PART
admet-1437	103	14	100	100	NUM
admet-1437	103	15	mm	mm	NOUN
admet-1437	103	16	length	length	NOUN
admet-1437	103	17	was	be	AUX
admet-1437	103	18	used	use	VERB
admet-1437	103	19	.	.	PUNCT
admet-1437	104	1	nanocrystal	nanocrystal	ADJ
admet-1437	104	2	suspensions	suspension	NOUN
admet-1437	104	3	were	be	AUX
admet-1437	104	4	filled	fill	VERB
admet-1437	104	5	into	into	ADP
admet-1437	104	6	the	the	DET
admet-1437	104	7	capillaries	capillary	NOUN
admet-1437	104	8	using	use	VERB
admet-1437	104	9	a	a	DET
admet-1437	104	10	special	special	ADJ
admet-1437	104	11	0.5	0.5	NUM
admet-1437	104	12	mm	mm	NOUN
admet-1437	104	13	od	od	NOUN
admet-1437	104	14	cannula	cannula	NOUN
admet-1437	104	15	.	.	PUNCT
admet-1437	105	1	filled	fill	VERB
admet-1437	105	2	cannulas	cannula	NOUN
admet-1437	105	3	were	be	AUX
admet-1437	105	4	immediately	immediately	ADV
admet-1437	105	5	afterwards	afterwards	ADV
admet-1437	105	6	closed	close	VERB
admet-1437	105	7	with	with	ADP
admet-1437	105	8	a	a	DET
admet-1437	105	9	small	small	ADJ
admet-1437	105	10	plug	plug	NOUN
admet-1437	105	11	of	of	ADP
admet-1437	105	12	malleable	malleable	ADJ
admet-1437	105	13	waxy	waxy	NOUN
admet-1437	105	14	material	material	NOUN
admet-1437	105	15	.	.	PUNCT
admet-1437	106	1	capillaries	capillary	NOUN
admet-1437	106	2	were	be	AUX
admet-1437	106	3	spun	spin	VERB
admet-1437	106	4	with	with	ADP
admet-1437	106	5	2	2	NUM
admet-1437	106	6	hz	hz	VERB
admet-1437	106	7	and	and	CCONJ
admet-1437	106	8	a	a	DET
admet-1437	106	9	scan	scan	ADJ
admet-1437	106	10	speed	speed	NOUN
admet-1437	106	11	of	of	ADP
admet-1437	106	12	0.1	0.1	NUM
admet-1437	106	13	°	°	NOUN
admet-1437	106	14	/min	/min	NOUN
admet-1437	106	15	was	be	AUX
admet-1437	106	16	used	use	VERB
admet-1437	106	17	.	.	PUNCT
admet-1437	107	1	modeling	modeling	NOUN
admet-1437	107	2	methods	method	NOUN
admet-1437	107	3	the	the	DET
admet-1437	107	4	diffusion	diffusion	NOUN
admet-1437	107	5	-	-	PUNCT
admet-1437	107	6	limited	limit	VERB
admet-1437	107	7	dissolution	dissolution	NOUN
admet-1437	107	8	of	of	ADP
admet-1437	107	9	solids	solid	NOUN
admet-1437	107	10	in	in	ADP
admet-1437	107	11	a	a	DET
admet-1437	107	12	surrounding	surround	VERB
admet-1437	107	13	liquid	liquid	ADJ
admet-1437	107	14	phase	phase	NOUN
admet-1437	107	15	is	be	AUX
admet-1437	107	16	described	describe	VERB
admet-1437	107	17	by	by	ADP
admet-1437	107	18	the	the	DET
admet-1437	107	19	noyes	noyes	PROPN
admet-1437	107	20	-	-	PUNCT
admet-1437	107	21	whitney	whitney	PROPN
admet-1437	107	22	/	/	SYM
admet-1437	107	23	nernst	nernst	PROPN
admet-1437	107	24	-	-	PUNCT
admet-1437	107	25	brunner	brunner	NOUN
admet-1437	107	26	equation	equation	NOUN
admet-1437	107	27	[	[	X
admet-1437	107	28	62,63	62,63	NOUN
admet-1437	107	29	]	]	X
admet-1437	107	30	:	:	PUNCT
admet-1437	108	1	d𝑚	d𝑚	INTJ
admet-1437	108	2	d𝑡	d𝑡	INTJ
admet-1437	109	1	=	=	PUNCT
admet-1437	109	2	𝐴∙𝐷	𝐴∙𝐷	PROPN
admet-1437	109	3	𝛿	𝛿	X
admet-1437	109	4	(	(	PUNCT
admet-1437	109	5	𝑠	𝑠	INTJ
admet-1437	109	6	−	−	PROPN
admet-1437	109	7	𝑐l	𝑐l	NOUN
admet-1437	109	8	)	)	PUNCT
admet-1437	109	9	(	(	PUNCT
admet-1437	109	10	1	1	X
admet-1437	109	11	)	)	PUNCT
admet-1437	109	12	the	the	DET
admet-1437	109	13	dissolution	dissolution	NOUN
admet-1437	109	14	rate	rate	NOUN
admet-1437	109	15	dm	dm	PROPN
admet-1437	109	16	/	/	SYM
admet-1437	109	17	dt	dt	NOUN
admet-1437	109	18	is	be	AUX
admet-1437	109	19	a	a	DET
admet-1437	109	20	function	function	NOUN
admet-1437	109	21	of	of	ADP
admet-1437	109	22	the	the	DET
admet-1437	109	23	surface	surface	NOUN
admet-1437	109	24	area	area	NOUN
admet-1437	109	25	of	of	ADP
admet-1437	109	26	the	the	DET
admet-1437	109	27	solids	solid	NOUN
admet-1437	109	28	a	a	PRON
admet-1437	109	29	,	,	PUNCT
admet-1437	109	30	the	the	DET
admet-1437	109	31	diffusion	diffusion	NOUN
admet-1437	109	32	coefficient	coefficient	NOUN
admet-1437	109	33	of	of	ADP
admet-1437	109	34	the	the	DET
admet-1437	109	35	solute	solute	NOUN
admet-1437	109	36	d	d	PROPN
admet-1437	109	37	,	,	PUNCT
admet-1437	109	38	the	the	DET
admet-1437	109	39	diffusion	diffusion	NOUN
admet-1437	109	40	boundary	boundary	ADJ
admet-1437	109	41	layer	layer	NOUN
admet-1437	109	42	thickness	thickness	NOUN
admet-1437	109	43	around	around	ADP
admet-1437	109	44	the	the	DET
admet-1437	109	45	solid	solid	PROPN
admet-1437	109	46	δ	δ	PROPN
admet-1437	109	47	,	,	PUNCT
admet-1437	109	48	the	the	DET
admet-1437	109	49	saturation	saturation	NOUN
admet-1437	109	50	solubility	solubility	NOUN
admet-1437	109	51	of	of	ADP
admet-1437	109	52	the	the	DET
admet-1437	109	53	solute	solute	NOUN
admet-1437	109	54	s	s	X
admet-1437	109	55	and	and	CCONJ
admet-1437	109	56	the	the	DET
admet-1437	109	57	time	time	NOUN
admet-1437	109	58	-	-	PUNCT
admet-1437	109	59	dependent	dependent	ADJ
admet-1437	109	60	concentration	concentration	NOUN
admet-1437	109	61	in	in	ADP
admet-1437	109	62	the	the	DET
admet-1437	109	63	liquid	liquid	ADJ
admet-1437	109	64	phase	phase	NOUN
admet-1437	109	65	cl	cl	NOUN
admet-1437	109	66	.	.	PUNCT
admet-1437	110	1	this	this	DET
admet-1437	110	2	diffusion	diffusion	NOUN
admet-1437	110	3	-	-	PUNCT
admet-1437	110	4	based	base	VERB
admet-1437	110	5	approach	approach	NOUN
admet-1437	110	6	assumes	assume	VERB
admet-1437	110	7	saturation	saturation	NOUN
admet-1437	110	8	conditions	condition	NOUN
admet-1437	110	9	at	at	ADP
admet-1437	110	10	the	the	DET
admet-1437	110	11	solid	solid	PROPN
admet-1437	110	12	’s	’s	PART
admet-1437	110	13	surface	surface	NOUN
admet-1437	110	14	followed	follow	VERB
admet-1437	110	15	by	by	ADP
admet-1437	110	16	diffusion	diffusion	NOUN
admet-1437	110	17	of	of	ADP
admet-1437	110	18	the	the	DET
admet-1437	110	19	solute	solute	ADJ
admet-1437	110	20	molecules	molecule	NOUN
admet-1437	110	21	through	through	ADP
admet-1437	110	22	the	the	DET
admet-1437	110	23	diffusion	diffusion	NOUN
admet-1437	110	24	boundary	boundary	ADJ
admet-1437	110	25	layer	layer	NOUN
admet-1437	110	26	into	into	ADP
admet-1437	110	27	the	the	DET
admet-1437	110	28	surrounding	surround	VERB
admet-1437	110	29	liquid	liquid	NOUN
admet-1437	110	30	with	with	ADP
admet-1437	110	31	concentration	concentration	NOUN
admet-1437	110	32	cl	cl	NOUN
admet-1437	110	33	,	,	PUNCT
admet-1437	110	34	assuming	assume	VERB
admet-1437	110	35	a	a	DET
admet-1437	110	36	linear	linear	ADJ
admet-1437	110	37	concentration	concentration	NOUN
admet-1437	110	38	gradient	gradient	NOUN
admet-1437	110	39	across	across	ADP
admet-1437	110	40	the	the	DET
admet-1437	110	41	diffusion	diffusion	NOUN
admet-1437	110	42	boundary	boundary	ADJ
admet-1437	110	43	layer	layer	NOUN
admet-1437	110	44	.	.	PUNCT
admet-1437	111	1	the	the	DET
admet-1437	111	2	diffusion	diffusion	NOUN
admet-1437	111	3	coefficient	coefficient	NOUN
admet-1437	111	4	d	d	PROPN
admet-1437	111	5	is	be	AUX
admet-1437	111	6	calculated	calculate	VERB
admet-1437	111	7	according	accord	VERB
admet-1437	111	8	to	to	ADP
admet-1437	111	9	the	the	DET
admet-1437	111	10	stokes	stokes	PROPN
admet-1437	111	11	-	-	PUNCT
admet-1437	111	12	einstein	einstein	NOUN
admet-1437	111	13	equation	equation	NOUN
admet-1437	111	14	:	:	PUNCT
admet-1437	111	15	𝐷	𝐷	NOUN
admet-1437	111	16	=	=	SYM
admet-1437	111	17	𝑘b∙𝑇	𝑘b∙𝑇	PROPN
admet-1437	111	18	6∙𝜋∙𝜂∙𝑅0	6∙𝜋∙𝜂∙𝑅0	PROPN
admet-1437	111	19	(	(	PUNCT
admet-1437	111	20	2	2	X
admet-1437	111	21	)	)	PUNCT
admet-1437	111	22	where	where	SCONJ
admet-1437	111	23	kb	kb	PROPN
admet-1437	111	24	is	be	AUX
admet-1437	111	25	the	the	DET
admet-1437	111	26	boltzmann	boltzmann	PROPN
admet-1437	111	27	constant	constant	PROPN
admet-1437	111	28	,	,	PUNCT
admet-1437	111	29	t	t	PROPN
admet-1437	111	30	the	the	DET
admet-1437	111	31	temperature	temperature	NOUN
admet-1437	111	32	,	,	PUNCT
admet-1437	111	33	η	η	PROPN
admet-1437	111	34	the	the	DET
admet-1437	111	35	dynamic	dynamic	ADJ
admet-1437	111	36	viscosity	viscosity	NOUN
admet-1437	111	37	of	of	ADP
admet-1437	111	38	the	the	DET
admet-1437	111	39	liquid	liquid	NOUN
admet-1437	111	40	and	and	CCONJ
admet-1437	111	41	r0	r0	VERB
admet-1437	111	42	the	the	DET
admet-1437	111	43	hydrodynamic	hydrodynamic	ADJ
admet-1437	111	44	radius	radius	NOUN
admet-1437	111	45	of	of	ADP
admet-1437	111	46	the	the	DET
admet-1437	111	47	diffusing	diffuse	VERB
admet-1437	111	48	molecule	molecule	NOUN
admet-1437	111	49	.	.	PUNCT
admet-1437	112	1	r0	r0	NOUN
admet-1437	112	2	is	be	AUX
admet-1437	112	3	calculated	calculate	VERB
admet-1437	112	4	based	base	VERB
admet-1437	112	5	on	on	ADP
admet-1437	112	6	the	the	DET
admet-1437	112	7	molar	molar	ADJ
admet-1437	112	8	volume	volume	NOUN
admet-1437	112	9	of	of	ADP
admet-1437	112	10	the	the	DET
admet-1437	112	11	dissolving	dissolve	VERB
admet-1437	112	12	compound	compound	NOUN
admet-1437	112	13	vm	vm	PROPN
admet-1437	112	14	,	,	PUNCT
admet-1437	112	15	assuming	assume	VERB
admet-1437	112	16	a	a	DET
admet-1437	112	17	spherical	spherical	ADJ
admet-1437	112	18	geometry	geometry	NOUN
admet-1437	112	19	of	of	ADP
admet-1437	112	20	the	the	DET
admet-1437	112	21	diffusing	diffuse	VERB
admet-1437	112	22	molecule	molecule	NOUN
admet-1437	112	23	.	.	PUNCT
admet-1437	113	1	the	the	DET
admet-1437	113	2	diffusion	diffusion	NOUN
admet-1437	113	3	boundary	boundary	ADJ
admet-1437	113	4	layer	layer	NOUN
admet-1437	113	5	thickness	thickness	NOUN
admet-1437	113	6	is	be	AUX
admet-1437	113	7	described	describe	VERB
admet-1437	113	8	by	by	ADP
admet-1437	113	9	prandtl	prandtl	NOUN
admet-1437	113	10	’s	’s	PART
admet-1437	113	11	boundary	boundary	ADJ
admet-1437	113	12	layer	layer	NOUN
admet-1437	113	13	theory	theory	NOUN
admet-1437	113	14	for	for	ADP
admet-1437	113	15	macroscopic	macroscopic	ADJ
admet-1437	113	16	systems	system	NOUN
admet-1437	113	17	,	,	PUNCT
admet-1437	113	18	in	in	ADP
admet-1437	113	19	which	which	PRON
admet-1437	113	20	the	the	DET
admet-1437	113	21	thickness	thickness	NOUN
admet-1437	113	22	of	of	ADP
admet-1437	113	23	the	the	DET
admet-1437	113	24	diffusion	diffusion	NOUN
admet-1437	113	25	boundary	boundary	ADJ
admet-1437	113	26	layer	layer	NOUN
admet-1437	113	27	depends	depend	VERB
admet-1437	113	28	on	on	ADP
admet-1437	113	29	the	the	DET
admet-1437	113	30	velocity	velocity	NOUN
admet-1437	113	31	of	of	ADP
admet-1437	113	32	the	the	DET
admet-1437	113	33	surrounding	surround	VERB
admet-1437	113	34	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	113	35	bonhoeffer	bonhoeffer	PROPN
admet-1437	113	36	et	et	PROPN
admet-1437	113	37	al	al	PROPN
admet-1437	113	38	.	.	PROPN
admet-1437	113	39	admet	admet	PROPN
admet-1437	113	40	&	&	CCONJ
admet-1437	113	41	dmpk	dmpk	PROPN
admet-1437	113	42	10(4	10(4	NUM
admet-1437	113	43	)	)	PUNCT
admet-1437	113	44	(	(	PUNCT
admet-1437	113	45	2022	2022	NUM
admet-1437	113	46	)	)	PUNCT
admet-1437	113	47	253	253	NUM
admet-1437	113	48	-	-	SYM
admet-1437	113	49	287	287	NUM
admet-1437	113	50	258	258	NUM
admet-1437	113	51	liquid	liquid	NOUN
admet-1437	113	52	in	in	ADP
admet-1437	113	53	relation	relation	NOUN
admet-1437	113	54	to	to	ADP
admet-1437	113	55	the	the	DET
admet-1437	113	56	solid	solid	ADJ
admet-1437	113	57	surface	surface	NOUN
admet-1437	114	1	[	[	X
admet-1437	114	2	64	64	NUM
admet-1437	114	3	]	]	PUNCT
admet-1437	114	4	.	.	PUNCT
admet-1437	115	1	this	this	DET
admet-1437	115	2	concept	concept	NOUN
admet-1437	115	3	is	be	AUX
admet-1437	115	4	no	no	ADV
admet-1437	115	5	longer	long	ADV
admet-1437	115	6	applicable	applicable	ADJ
admet-1437	115	7	for	for	ADP
admet-1437	115	8	particles	particle	NOUN
admet-1437	115	9	smaller	small	ADJ
admet-1437	115	10	than	than	ADP
admet-1437	115	11	1	1	NUM
admet-1437	115	12	µm	µm	NOUN
admet-1437	115	13	since	since	SCONJ
admet-1437	115	14	the	the	DET
admet-1437	115	15	particles	particle	NOUN
admet-1437	115	16	practically	practically	ADV
admet-1437	115	17	follow	follow	VERB
admet-1437	115	18	the	the	DET
admet-1437	115	19	liquid	liquid	ADJ
admet-1437	115	20	flow	flow	NOUN
admet-1437	115	21	due	due	ADP
admet-1437	115	22	to	to	ADP
admet-1437	115	23	a	a	DET
admet-1437	115	24	lack	lack	NOUN
admet-1437	115	25	of	of	ADP
admet-1437	115	26	inertia	inertia	NOUN
admet-1437	115	27	and	and	CCONJ
admet-1437	115	28	the	the	DET
admet-1437	115	29	relative	relative	ADJ
admet-1437	115	30	velocity	velocity	NOUN
admet-1437	115	31	approaches	approach	VERB
admet-1437	115	32	zero	zero	NUM
admet-1437	115	33	[	[	X
admet-1437	115	34	65,66	65,66	NOUN
admet-1437	115	35	]	]	X
admet-1437	115	36	.	.	PUNCT
admet-1437	116	1	the	the	DET
admet-1437	116	2	exact	exact	ADJ
admet-1437	116	3	behavior	behavior	NOUN
admet-1437	116	4	of	of	ADP
admet-1437	116	5	the	the	DET
admet-1437	116	6	diffusion	diffusion	NOUN
admet-1437	116	7	boundary	boundary	ADJ
admet-1437	116	8	layer	layer	NOUN
admet-1437	116	9	thickness	thickness	NOUN
admet-1437	116	10	for	for	ADP
admet-1437	116	11	particles	particle	NOUN
admet-1437	116	12	smaller	small	ADJ
admet-1437	116	13	than	than	ADP
admet-1437	116	14	1	1	NUM
admet-1437	116	15	µm	µm	NOUN
admet-1437	116	16	is	be	AUX
admet-1437	116	17	not	not	PART
admet-1437	116	18	fully	fully	ADV
admet-1437	116	19	understood	understand	VERB
admet-1437	116	20	.	.	PUNCT
admet-1437	117	1	however	however	ADV
admet-1437	117	2	,	,	PUNCT
admet-1437	117	3	the	the	DET
admet-1437	117	4	most	most	ADV
admet-1437	117	5	frequent	frequent	ADJ
admet-1437	117	6	and	and	CCONJ
admet-1437	117	7	accepted	accepted	ADJ
admet-1437	117	8	approach	approach	NOUN
admet-1437	117	9	assumes	assume	VERB
admet-1437	117	10	a	a	DET
admet-1437	117	11	diffusion	diffusion	NOUN
admet-1437	117	12	boundary	boundary	ADJ
admet-1437	117	13	layer	layer	NOUN
admet-1437	117	14	thickness	thickness	NOUN
admet-1437	117	15	equal	equal	ADJ
admet-1437	117	16	to	to	ADP
admet-1437	117	17	the	the	DET
admet-1437	117	18	particle	particle	NOUN
admet-1437	117	19	radius	radius	NOUN
admet-1437	117	20	for	for	ADP
admet-1437	117	21	such	such	ADJ
admet-1437	117	22	small	small	ADJ
admet-1437	117	23	particles	particle	NOUN
admet-1437	117	24	[	[	X
admet-1437	117	25	65,67	65,67	NOUN
admet-1437	117	26	-	-	SYM
admet-1437	117	27	71	71	NUM
admet-1437	117	28	]	]	PUNCT
admet-1437	117	29	:	:	PUNCT
admet-1437	117	30	𝛿	𝛿	ADJ
admet-1437	117	31	=	=	ADJ
admet-1437	117	32	𝑟	𝑟	NOUN
admet-1437	117	33	=	=	SYM
admet-1437	117	34	𝑥	𝑥	SYM
admet-1437	117	35	2	2	NUM
admet-1437	117	36	(	(	PUNCT
admet-1437	117	37	3	3	NUM
admet-1437	117	38	)	)	PUNCT
admet-1437	117	39	the	the	DET
admet-1437	117	40	increase	increase	NOUN
admet-1437	117	41	of	of	ADP
admet-1437	117	42	the	the	DET
admet-1437	117	43	solubility	solubility	NOUN
admet-1437	117	44	with	with	ADP
admet-1437	117	45	the	the	DET
admet-1437	117	46	decrease	decrease	NOUN
admet-1437	117	47	in	in	ADP
admet-1437	117	48	particle	particle	NOUN
admet-1437	117	49	size	size	NOUN
admet-1437	117	50	is	be	AUX
admet-1437	117	51	described	describe	VERB
admet-1437	117	52	by	by	ADP
admet-1437	117	53	the	the	DET
admet-1437	117	54	ostwald	ostwald	NOUN
admet-1437	117	55	-	-	PUNCT
admet-1437	117	56	freundlich	freundlich	ADJ
admet-1437	117	57	equation	equation	NOUN
admet-1437	117	58	[	[	X
admet-1437	117	59	72	72	NUM
admet-1437	117	60	]	]	SYM
admet-1437	117	61	:	:	PUNCT
admet-1437	117	62	𝑠app	𝑠app	NOUN
admet-1437	117	63	=	=	NOUN
admet-1437	117	64	𝑠0	𝑠0	PROPN
admet-1437	117	65	∙	∙	PROPN
admet-1437	117	66	𝑒	𝑒	X
admet-1437	117	67	(	(	PUNCT
admet-1437	117	68	2∙𝑉m∙𝜎sl	2∙𝑉m∙𝜎sl	NUM
admet-1437	117	69	𝑅∙𝑇∙𝑟	𝑅∙𝑇∙𝑟	NUM
admet-1437	117	70	)	)	PUNCT
admet-1437	117	71	(	(	PUNCT
admet-1437	117	72	4	4	X
admet-1437	117	73	)	)	PUNCT
admet-1437	117	74	where	where	SCONJ
admet-1437	117	75	sapp	sapp	PROPN
admet-1437	117	76	is	be	AUX
admet-1437	117	77	the	the	DET
admet-1437	117	78	apparent	apparent	ADJ
admet-1437	117	79	solubility	solubility	NOUN
admet-1437	117	80	,	,	PUNCT
admet-1437	117	81	s0	s0	PROPN
admet-1437	117	82	the	the	DET
admet-1437	117	83	thermodynamic	thermodynamic	ADJ
admet-1437	117	84	solubility	solubility	NOUN
admet-1437	117	85	for	for	ADP
admet-1437	117	86	coarse	coarse	ADJ
admet-1437	117	87	particles	particle	NOUN
admet-1437	117	88	𝑥	𝑥	PROPN
admet-1437	117	89	≫	≫	NOUN
admet-1437	117	90	1	1	NUM
admet-1437	117	91	µm	µm	NOUN
admet-1437	117	92	,	,	PUNCT
admet-1437	117	93	σsl	σsl	VERB
admet-1437	117	94	the	the	DET
admet-1437	117	95	interfacial	interfacial	ADJ
admet-1437	117	96	energy	energy	NOUN
admet-1437	117	97	between	between	ADP
admet-1437	117	98	solid	solid	ADJ
admet-1437	117	99	and	and	CCONJ
admet-1437	117	100	liquid	liquid	ADJ
admet-1437	117	101	phase	phase	NOUN
admet-1437	117	102	,	,	PUNCT
admet-1437	117	103	r	r	NOUN
admet-1437	117	104	the	the	DET
admet-1437	117	105	particle	particle	NOUN
admet-1437	117	106	radius	radius	NOUN
admet-1437	117	107	,	,	PUNCT
admet-1437	117	108	vm	vm	PROPN
admet-1437	117	109	the	the	DET
admet-1437	117	110	molar	molar	ADJ
admet-1437	117	111	volume	volume	NOUN
admet-1437	117	112	of	of	ADP
admet-1437	117	113	the	the	DET
admet-1437	117	114	dissolving	dissolve	VERB
admet-1437	117	115	compound	compound	NOUN
admet-1437	117	116	,	,	PUNCT
admet-1437	117	117	r	r	NOUN
admet-1437	117	118	the	the	DET
admet-1437	117	119	universal	universal	ADJ
admet-1437	117	120	gas	gas	NOUN
admet-1437	117	121	constant	constant	ADJ
admet-1437	117	122	and	and	CCONJ
admet-1437	117	123	t	t	X
admet-1437	117	124	the	the	DET
admet-1437	117	125	temperature	temperature	NOUN
admet-1437	117	126	.	.	PUNCT
admet-1437	118	1	according	accord	VERB
admet-1437	118	2	to	to	ADP
admet-1437	118	3	equation	equation	NOUN
admet-1437	118	4	(	(	PUNCT
admet-1437	118	5	4	4	NUM
admet-1437	118	6	)	)	PUNCT
admet-1437	118	7	,	,	PUNCT
admet-1437	118	8	the	the	DET
admet-1437	118	9	apparent	apparent	ADJ
admet-1437	118	10	solubility	solubility	NOUN
admet-1437	118	11	increases	increase	VERB
admet-1437	118	12	with	with	ADP
admet-1437	118	13	decreasing	decrease	VERB
admet-1437	118	14	particle	particle	NOUN
admet-1437	118	15	size	size	NOUN
admet-1437	118	16	.	.	PUNCT
admet-1437	119	1	this	this	DET
admet-1437	119	2	effect	effect	NOUN
admet-1437	119	3	becomes	become	VERB
admet-1437	119	4	notable	notable	ADJ
admet-1437	119	5	for	for	ADP
admet-1437	119	6	particles	particle	NOUN
admet-1437	119	7	𝑥	𝑥	X
admet-1437	119	8	≪	≪	ADJ
admet-1437	119	9	1	1	NUM
admet-1437	119	10	µm	µm	NUM
admet-1437	119	11	and	and	CCONJ
admet-1437	119	12	has	have	AUX
admet-1437	119	13	been	be	AUX
admet-1437	119	14	experimentally	experimentally	ADV
admet-1437	119	15	demonstrated	demonstrate	VERB
admet-1437	119	16	[	[	X
admet-1437	119	17	8,43	8,43	NUM
admet-1437	119	18	-	-	SYM
admet-1437	119	19	46	46	NUM
admet-1437	119	20	]	]	PUNCT
admet-1437	119	21	.	.	PUNCT
admet-1437	120	1	a	a	DET
admet-1437	120	2	numerical	numerical	ADJ
admet-1437	120	3	model	model	NOUN
admet-1437	120	4	was	be	AUX
admet-1437	120	5	established	establish	VERB
admet-1437	120	6	,	,	PUNCT
admet-1437	120	7	combining	combine	VERB
admet-1437	120	8	equations	equation	NOUN
admet-1437	120	9	(	(	PUNCT
admet-1437	120	10	1	1	NUM
admet-1437	120	11	)	)	PUNCT
admet-1437	120	12	,	,	PUNCT
admet-1437	120	13	(	(	PUNCT
admet-1437	120	14	3	3	X
admet-1437	120	15	)	)	PUNCT
admet-1437	120	16	and	and	CCONJ
admet-1437	120	17	(	(	PUNCT
admet-1437	120	18	4	4	X
admet-1437	120	19	)	)	PUNCT
admet-1437	120	20	to	to	PART
admet-1437	120	21	describe	describe	VERB
admet-1437	120	22	the	the	DET
admet-1437	120	23	dissolution	dissolution	NOUN
admet-1437	120	24	of	of	ADP
admet-1437	120	25	a	a	DET
admet-1437	120	26	sample	sample	NOUN
admet-1437	120	27	of	of	ADP
admet-1437	120	28	small	small	ADJ
admet-1437	120	29	particles	particle	NOUN
admet-1437	120	30	x	x	SYM
admet-1437	120	31	≪	≪	X
admet-1437	120	32	1	1	NUM
admet-1437	120	33	µm	µm	NOUN
admet-1437	120	34	.	.	PUNCT
admet-1437	121	1	any	any	DET
admet-1437	121	2	true	true	ADJ
admet-1437	121	3	sample	sample	NOUN
admet-1437	121	4	of	of	ADP
admet-1437	121	5	particles	particle	NOUN
admet-1437	121	6	is	be	AUX
admet-1437	121	7	polydisperse	polydisperse	NOUN
admet-1437	121	8	and	and	CCONJ
admet-1437	121	9	not	not	PART
admet-1437	121	10	monodisperse	monodisperse	NOUN
admet-1437	121	11	.	.	PUNCT
admet-1437	122	1	therefore	therefore	ADV
admet-1437	122	2	,	,	PUNCT
admet-1437	122	3	realistic	realistic	ADJ
admet-1437	122	4	samples	sample	NOUN
admet-1437	122	5	should	should	AUX
admet-1437	122	6	be	be	AUX
admet-1437	122	7	described	describe	VERB
admet-1437	122	8	by	by	ADP
admet-1437	122	9	a	a	DET
admet-1437	122	10	particle	particle	NOUN
admet-1437	122	11	size	size	NOUN
admet-1437	122	12	distribution	distribution	NOUN
admet-1437	122	13	.	.	PUNCT
admet-1437	123	1	each	each	DET
admet-1437	123	2	particle	particle	NOUN
admet-1437	123	3	within	within	ADP
admet-1437	123	4	the	the	DET
admet-1437	123	5	particle	particle	NOUN
admet-1437	123	6	size	size	NOUN
admet-1437	123	7	distribution	distribution	NOUN
admet-1437	123	8	with	with	ADP
admet-1437	123	9	its	its	PRON
admet-1437	123	10	specific	specific	ADJ
admet-1437	123	11	particle	particle	NOUN
admet-1437	123	12	size	size	NOUN
admet-1437	123	13	exhibits	exhibit	VERB
admet-1437	123	14	its	its	PRON
admet-1437	123	15	own	own	ADJ
admet-1437	123	16	specific	specific	ADJ
admet-1437	123	17	apparent	apparent	ADJ
admet-1437	123	18	solubility	solubility	NOUN
admet-1437	123	19	.	.	PUNCT
admet-1437	124	1	depending	depend	VERB
admet-1437	124	2	on	on	ADP
admet-1437	124	3	the	the	DET
admet-1437	124	4	particle	particle	NOUN
admet-1437	124	5	size	size	NOUN
admet-1437	124	6	distribution	distribution	NOUN
admet-1437	124	7	,	,	PUNCT
admet-1437	124	8	the	the	DET
admet-1437	124	9	apparent	apparent	ADJ
admet-1437	124	10	solubility	solubility	NOUN
admet-1437	124	11	can	can	AUX
admet-1437	124	12	vary	vary	VERB
admet-1437	124	13	notably	notably	ADV
admet-1437	124	14	from	from	ADP
admet-1437	124	15	one	one	NUM
admet-1437	124	16	end	end	NOUN
admet-1437	124	17	of	of	ADP
admet-1437	124	18	the	the	DET
admet-1437	124	19	particle	particle	NOUN
admet-1437	124	20	size	size	NOUN
admet-1437	124	21	distribution	distribution	NOUN
admet-1437	124	22	to	to	ADP
admet-1437	124	23	the	the	DET
admet-1437	124	24	other	other	ADJ
admet-1437	124	25	.	.	PUNCT
admet-1437	125	1	therefore	therefore	ADV
admet-1437	125	2	,	,	PUNCT
admet-1437	125	3	the	the	DET
admet-1437	125	4	entire	entire	ADJ
admet-1437	125	5	particle	particle	NOUN
admet-1437	125	6	size	size	NOUN
admet-1437	125	7	distribution	distribution	NOUN
admet-1437	125	8	must	must	AUX
admet-1437	125	9	be	be	AUX
admet-1437	125	10	considered	consider	VERB
admet-1437	125	11	to	to	PART
admet-1437	125	12	accurately	accurately	ADV
admet-1437	125	13	describe	describe	VERB
admet-1437	125	14	the	the	DET
admet-1437	125	15	dissolution	dissolution	NOUN
admet-1437	125	16	of	of	ADP
admet-1437	125	17	a	a	DET
admet-1437	125	18	particle	particle	NOUN
admet-1437	125	19	system	system	NOUN
admet-1437	125	20	with	with	ADP
admet-1437	125	21	x	x	PUNCT
admet-1437	125	22	≪	≪	ADJ
admet-1437	125	23	1	1	NUM
admet-1437	125	24	µm	µm	NOUN
admet-1437	125	25	.	.	PUNCT
admet-1437	126	1	a	a	DET
admet-1437	126	2	particle	particle	NOUN
admet-1437	126	3	size	size	NOUN
admet-1437	126	4	distribution	distribution	NOUN
admet-1437	126	5	with	with	ADP
admet-1437	126	6	appropriate	appropriate	ADJ
admet-1437	126	7	discretization	discretization	NOUN
admet-1437	126	8	is	be	AUX
admet-1437	126	9	required	require	VERB
admet-1437	126	10	for	for	ADP
admet-1437	126	11	the	the	DET
admet-1437	126	12	numerical	numerical	ADJ
admet-1437	126	13	model	model	NOUN
admet-1437	126	14	to	to	PART
admet-1437	126	15	minimize	minimize	VERB
admet-1437	126	16	the	the	DET
admet-1437	126	17	variability	variability	NOUN
admet-1437	126	18	of	of	ADP
admet-1437	126	19	the	the	DET
admet-1437	126	20	calculated	calculate	VERB
admet-1437	126	21	results	result	NOUN
admet-1437	126	22	.	.	PUNCT
admet-1437	127	1	pcs	pc	NOUN
admet-1437	127	2	measurements	measurement	NOUN
admet-1437	127	3	yield	yield	VERB
admet-1437	127	4	the	the	DET
admet-1437	127	5	mean	mean	ADJ
admet-1437	127	6	particle	particle	NOUN
admet-1437	127	7	size	size	NOUN
admet-1437	127	8	(	(	PUNCT
admet-1437	127	9	xpcs	xpcs	PROPN
admet-1437	127	10	)	)	PUNCT
admet-1437	127	11	and	and	CCONJ
admet-1437	127	12	the	the	DET
admet-1437	127	13	polydispersity	polydispersity	NOUN
admet-1437	127	14	index	index	NOUN
admet-1437	127	15	(	(	PUNCT
admet-1437	127	16	pi	pi	NOUN
admet-1437	127	17	)	)	PUNCT
admet-1437	127	18	.	.	PUNCT
admet-1437	128	1	based	base	VERB
admet-1437	128	2	on	on	ADP
admet-1437	128	3	the	the	DET
admet-1437	128	4	refractive	refractive	ADJ
admet-1437	128	5	index	index	NOUN
admet-1437	128	6	of	of	ADP
admet-1437	128	7	the	the	DET
admet-1437	128	8	compound	compound	NOUN
admet-1437	128	9	and	and	CCONJ
admet-1437	128	10	the	the	DET
admet-1437	128	11	liquid	liquid	NOUN
admet-1437	128	12	,	,	PUNCT
admet-1437	128	13	the	the	DET
admet-1437	128	14	volume	volume	NOUN
admet-1437	128	15	-	-	PUNCT
admet-1437	128	16	based	base	VERB
admet-1437	128	17	(	(	PUNCT
admet-1437	128	18	q3	q3	NOUN
admet-1437	128	19	)	)	PUNCT
admet-1437	128	20	particle	particle	NOUN
admet-1437	128	21	size	size	NOUN
admet-1437	128	22	distribution	distribution	NOUN
admet-1437	128	23	data	datum	NOUN
admet-1437	128	24	can	can	AUX
admet-1437	128	25	be	be	AUX
admet-1437	128	26	obtained	obtain	VERB
admet-1437	128	27	as	as	ADP
admet-1437	128	28	percentiles	percentile	NOUN
admet-1437	128	29	for	for	ADP
admet-1437	128	30	x10,3	x10,3	PROPN
admet-1437	128	31	,	,	PUNCT
admet-1437	128	32	x20,3	x20,3	NOUN
admet-1437	128	33	to	to	ADP
admet-1437	128	34	x80,3	x80,3	PROPN
admet-1437	128	35	,	,	PUNCT
admet-1437	128	36	x90,3	x90,3	PROPN
admet-1437	128	37	.	.	PUNCT
admet-1437	129	1	finally	finally	ADV
admet-1437	129	2	,	,	PUNCT
admet-1437	129	3	these	these	DET
admet-1437	129	4	data	datum	NOUN
admet-1437	129	5	are	be	AUX
admet-1437	129	6	fitted	fit	VERB
admet-1437	129	7	using	use	VERB
admet-1437	129	8	a	a	DET
admet-1437	129	9	log	log	NOUN
admet-1437	129	10	-	-	PUNCT
admet-1437	129	11	normal	normal	ADJ
admet-1437	129	12	function	function	NOUN
admet-1437	129	13	and	and	CCONJ
admet-1437	129	14	discretized	discretize	VERB
admet-1437	129	15	in	in	ADP
admet-1437	129	16	999	999	NUM
admet-1437	129	17	classes	class	NOUN
admet-1437	129	18	of	of	ADP
admet-1437	129	19	the	the	DET
admet-1437	129	20	volume	volume	NOUN
admet-1437	129	21	-	-	PUNCT
admet-1437	129	22	based	base	VERB
admet-1437	129	23	(	(	PUNCT
admet-1437	129	24	q3	q3	NOUN
admet-1437	129	25	)	)	PUNCT
admet-1437	129	26	particle	particle	NOUN
admet-1437	129	27	size	size	NOUN
admet-1437	129	28	distribution	distribution	NOUN
admet-1437	129	29	,	,	PUNCT
admet-1437	129	30	obtaining	obtain	VERB
admet-1437	129	31	the	the	DET
admet-1437	129	32	percentiles	percentile	NOUN
admet-1437	129	33	x0.1,3	x0.1,3	PROPN
admet-1437	129	34	,	,	PUNCT
admet-1437	129	35	x0.2,3	x0.2,3	PROPN
admet-1437	129	36	to	to	ADP
admet-1437	129	37	x99.8,3	x99.8,3	NUM
admet-1437	129	38	,	,	PUNCT
admet-1437	129	39	x99.9,3	x99.9,3	PROPN
admet-1437	129	40	..	..	PUNCT
admet-1437	129	41	while	while	SCONJ
admet-1437	129	42	the	the	DET
admet-1437	129	43	fitted	fit	VERB
admet-1437	129	44	log	log	NOUN
admet-1437	129	45	-	-	PUNCT
admet-1437	129	46	normal	normal	ADJ
admet-1437	129	47	distribution	distribution	NOUN
admet-1437	129	48	matches	match	NOUN
admet-1437	129	49	well	well	ADV
admet-1437	129	50	the	the	DET
admet-1437	129	51	percentiles	percentile	NOUN
admet-1437	129	52	from	from	ADP
admet-1437	129	53	x10,3	x10,3	PROPN
admet-1437	129	54	to	to	ADP
admet-1437	129	55	x90,3	x90,3	PROPN
admet-1437	129	56	,	,	PUNCT
admet-1437	129	57	it	it	PRON
admet-1437	129	58	should	should	AUX
admet-1437	129	59	be	be	AUX
admet-1437	129	60	noted	note	VERB
admet-1437	129	61	that	that	SCONJ
admet-1437	129	62	a	a	DET
admet-1437	129	63	non	non	ADJ
admet-1437	129	64	-	-	ADJ
admet-1437	129	65	negligible	negligible	ADJ
admet-1437	129	66	uncertainty	uncertainty	NOUN
admet-1437	129	67	is	be	AUX
admet-1437	129	68	introduced	introduce	VERB
admet-1437	129	69	specifically	specifically	ADV
admet-1437	129	70	for	for	ADP
admet-1437	129	71	the	the	DET
admet-1437	129	72	ranges	range	NOUN
admet-1437	129	73	below	below	ADP
admet-1437	129	74	x10,3	x10,3	PROPN
admet-1437	129	75	and	and	CCONJ
admet-1437	129	76	above	above	ADV
admet-1437	129	77	x90,3	x90,3	PROPN
admet-1437	129	78	as	as	ADP
admet-1437	129	79	here	here	ADV
admet-1437	129	80	,	,	PUNCT
admet-1437	129	81	an	an	DET
admet-1437	129	82	extrapolation	extrapolation	NOUN
admet-1437	129	83	of	of	ADP
admet-1437	129	84	the	the	DET
admet-1437	129	85	experimental	experimental	ADJ
admet-1437	129	86	data	datum	NOUN
admet-1437	129	87	is	be	AUX
admet-1437	129	88	conducted	conduct	VERB
admet-1437	129	89	as	as	SCONJ
admet-1437	129	90	the	the	DET
admet-1437	129	91	true	true	ADJ
admet-1437	129	92	particle	particle	NOUN
admet-1437	129	93	size	size	NOUN
admet-1437	129	94	distribution	distribution	NOUN
admet-1437	129	95	is	be	AUX
admet-1437	129	96	not	not	PART
admet-1437	129	97	known	know	VERB
admet-1437	129	98	.	.	PUNCT
admet-1437	130	1	the	the	DET
admet-1437	130	2	following	follow	VERB
admet-1437	130	3	assumptions	assumption	NOUN
admet-1437	130	4	are	be	AUX
admet-1437	130	5	made	make	VERB
admet-1437	130	6	for	for	ADP
admet-1437	130	7	the	the	DET
admet-1437	130	8	numerical	numerical	ADJ
admet-1437	130	9	model	model	NOUN
admet-1437	130	10	:	:	PUNCT
admet-1437	130	11			ADJ
admet-1437	130	12	diffusion	diffusion	NOUN
admet-1437	130	13	-	-	PUNCT
admet-1437	130	14	controlled	control	VERB
admet-1437	130	15	dissolution	dissolution	NOUN
admet-1437	130	16	from	from	ADP
admet-1437	130	17	a	a	DET
admet-1437	130	18	planar	planar	ADJ
admet-1437	130	19	surface	surface	NOUN
admet-1437	130	20	with	with	ADP
admet-1437	130	21	linear	linear	ADJ
admet-1437	130	22	concentration	concentration	NOUN
admet-1437	130	23	gradient	gradient	NOUN
admet-1437	130	24	across	across	ADP
admet-1437	130	25	the	the	DET
admet-1437	130	26	diffusion	diffusion	NOUN
admet-1437	130	27	boundary	boundary	ADJ
admet-1437	130	28	layer	layer	NOUN
admet-1437	130	29	,	,	PUNCT
admet-1437	130	30			ADJ
admet-1437	130	31	perfectly	perfectly	ADV
admet-1437	130	32	mixed	mixed	ADJ
admet-1437	130	33	liquid	liquid	ADJ
admet-1437	130	34	phase	phase	NOUN
admet-1437	130	35	with	with	ADP
admet-1437	130	36	constant	constant	ADJ
admet-1437	130	37	temperature	temperature	NOUN
admet-1437	130	38	,	,	PUNCT
admet-1437	130	39			ADJ
admet-1437	130	40	spherical	spherical	ADJ
admet-1437	130	41	particles	particle	NOUN
admet-1437	130	42	,	,	PUNCT
admet-1437	130	43	ideally	ideally	ADV
admet-1437	130	44	dispersed	disperse	VERB
admet-1437	130	45	in	in	ADP
admet-1437	130	46	the	the	DET
admet-1437	130	47	dissolution	dissolution	NOUN
admet-1437	130	48	medium	medium	NOUN
admet-1437	130	49	,	,	PUNCT
admet-1437	130	50			NUM
admet-1437	130	51	no	no	DET
admet-1437	130	52	drug	drug	NOUN
admet-1437	130	53	-	-	PUNCT
admet-1437	130	54	drug	drug	NOUN
admet-1437	130	55	or	or	CCONJ
admet-1437	130	56	drug	drug	NOUN
admet-1437	130	57	-	-	PUNCT
admet-1437	130	58	excipient	excipient	NOUN
admet-1437	130	59	interactions	interaction	NOUN
admet-1437	130	60	,	,	PUNCT
admet-1437	130	61			NUM
admet-1437	130	62	no	no	DET
admet-1437	130	63	precipitation	precipitation	NOUN
admet-1437	130	64	/	/	SYM
admet-1437	130	65	crystallization	crystallization	NOUN
admet-1437	130	66	/	/	SYM
admet-1437	130	67	ostwald	ostwald	NOUN
admet-1437	130	68	ripening	ripening	NOUN
admet-1437	130	69	,	,	PUNCT
admet-1437	130	70	no	no	DET
admet-1437	130	71	agglomeration	agglomeration	NOUN
admet-1437	130	72	.	.	PUNCT
admet-1437	131	1	admet	admet	PROPN
admet-1437	131	2	&	&	CCONJ
admet-1437	131	3	dmpk	dmpk	PROPN
admet-1437	131	4	10(4	10(4	NUM
admet-1437	131	5	)	)	PUNCT
admet-1437	131	6	(	(	PUNCT
admet-1437	131	7	2022	2022	NUM
admet-1437	131	8	)	)	PUNCT
admet-1437	131	9	253	253	NUM
admet-1437	131	10	-	-	SYM
admet-1437	131	11	287	287	NUM
admet-1437	131	12	modeling	modeling	NOUN
admet-1437	131	13	of	of	ADP
admet-1437	131	14	drug	drug	NOUN
admet-1437	131	15	nanocrystals	nanocrystal	NOUN
admet-1437	131	16	dissolution	dissolution	NOUN
admet-1437	131	17	doi	doi	PROPN
admet-1437	131	18	:	:	PUNCT
admet-1437	131	19	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	131	20	259	259	NUM
admet-1437	131	21	figure	figure	NOUN
admet-1437	131	22	1	1	NUM
admet-1437	131	23	.	.	PUNCT
admet-1437	131	24	scheme	scheme	NOUN
admet-1437	131	25	for	for	ADP
admet-1437	131	26	the	the	DET
admet-1437	131	27	numerical	numerical	ADJ
admet-1437	131	28	calculation	calculation	NOUN
admet-1437	131	29	of	of	ADP
admet-1437	131	30	nanocrystal	nanocrystal	ADJ
admet-1437	131	31	dissolution	dissolution	NOUN
admet-1437	131	32	considering	consider	VERB
admet-1437	131	33	the	the	DET
admet-1437	131	34	ostwald	ostwald	NOUN
admet-1437	131	35	-	-	PUNCT
admet-1437	131	36	freundlich	freundlich	NOUN
admet-1437	131	37	and	and	CCONJ
admet-1437	131	38	noyes	noyes	PROPN
admet-1437	131	39	-	-	PUNCT
admet-1437	131	40	whitney	whitney	PROPN
admet-1437	131	41	/	/	SYM
admet-1437	131	42	nernst	nernst	PROPN
admet-1437	131	43	-	-	PUNCT
admet-1437	131	44	brunner	brunner	NOUN
admet-1437	131	45	equations	equation	NOUN
admet-1437	131	46	with	with	ADP
admet-1437	131	47	parameters	parameter	NOUN
admet-1437	131	48	:	:	PUNCT
admet-1437	131	49	time	time	NOUN
admet-1437	131	50	t	t	PROPN
admet-1437	131	51	,	,	PUNCT
admet-1437	131	52	time	time	NOUN
admet-1437	131	53	step	step	NOUN
admet-1437	131	54	∆t	∆t	PROPN
admet-1437	131	55	,	,	PUNCT
admet-1437	131	56	drug	drug	NOUN
admet-1437	131	57	concentration	concentration	NOUN
admet-1437	131	58	cl	cl	NOUN
admet-1437	131	59	,	,	PUNCT
admet-1437	131	60	drug	drug	NOUN
admet-1437	131	61	mass	mass	PROPN
admet-1437	131	62	m	m	PROPN
admet-1437	131	63	,	,	PUNCT
admet-1437	131	64	thermodynamic	thermodynamic	ADJ
admet-1437	131	65	solubility	solubility	NOUN
admet-1437	131	66	for	for	ADP
admet-1437	131	67	x	x	SYM
admet-1437	131	68	≫	≫	NOUN
admet-1437	131	69	1μm	1μm	NOUN
admet-1437	131	70	,	,	PUNCT
admet-1437	131	71	s0	s0	PROPN
admet-1437	131	72	,	,	PUNCT
admet-1437	131	73	apparent	apparent	ADJ
admet-1437	131	74	solubility	solubility	NOUN
admet-1437	131	75	sapp	sapp	PROPN
admet-1437	131	76	,	,	PUNCT
admet-1437	131	77	particle	particle	NOUN
admet-1437	131	78	size	size	NOUN
admet-1437	131	79	x	x	NOUN
admet-1437	131	80	,	,	PUNCT
admet-1437	131	81	particle	particle	NOUN
admet-1437	131	82	radius	radius	NOUN
admet-1437	131	83	r	r	NOUN
admet-1437	131	84	,	,	PUNCT
admet-1437	131	85	drug	drug	NOUN
admet-1437	131	86	molar	molar	PROPN
admet-1437	131	87	volume	volume	PROPN
admet-1437	131	88	vm	vm	PROPN
admet-1437	131	89	,	,	PUNCT
admet-1437	131	90	interfacial	interfacial	ADJ
admet-1437	131	91	energy	energy	NOUN
admet-1437	131	92	between	between	ADP
admet-1437	131	93	solid	solid	ADJ
admet-1437	131	94	drug	drug	NOUN
admet-1437	131	95	and	and	CCONJ
admet-1437	131	96	liquid	liquid	ADJ
admet-1437	131	97	phase	phase	NOUN
admet-1437	131	98	σsl	σsl	ADV
admet-1437	131	99	,	,	PUNCT
admet-1437	131	100	universal	universal	ADJ
admet-1437	131	101	gas	gas	NOUN
admet-1437	131	102	constant	constant	ADJ
admet-1437	131	103	r	r	NOUN
admet-1437	131	104	,	,	PUNCT
admet-1437	131	105	temperature	temperature	NOUN
admet-1437	131	106	t	t	NOUN
admet-1437	131	107	,	,	PUNCT
admet-1437	131	108	particle	particle	NOUN
admet-1437	131	109	volume	volume	NOUN
admet-1437	131	110	v	v	NOUN
admet-1437	131	111	,	,	PUNCT
admet-1437	131	112	particle	particle	NOUN
admet-1437	131	113	surface	surface	PROPN
admet-1437	131	114	area	area	NOUN
admet-1437	131	115	a	a	PRON
admet-1437	131	116	,	,	PUNCT
admet-1437	131	117	diffusion	diffusion	NOUN
admet-1437	131	118	coefficient	coefficient	NOUN
admet-1437	131	119	d	d	PROPN
admet-1437	131	120	,	,	PUNCT
admet-1437	131	121	density	density	NOUN
admet-1437	131	122	of	of	ADP
admet-1437	131	123	solid	solid	ADJ
admet-1437	131	124	drug	drug	NOUN
admet-1437	131	125	ρ	ρ	PROPN
admet-1437	131	126	,	,	PUNCT
admet-1437	131	127	diffusion	diffusion	NOUN
admet-1437	131	128	boundary	boundary	ADJ
admet-1437	131	129	layer	layer	NOUN
admet-1437	131	130	thickness	thickness	PROPN
admet-1437	131	131	δ	δ	PROPN
admet-1437	131	132	,	,	PUNCT
admet-1437	131	133	volume	volume	NOUN
admet-1437	131	134	of	of	ADP
admet-1437	131	135	dissolution	dissolution	PROPN
admet-1437	131	136	medium	medium	PROPN
admet-1437	131	137	vl	vl	PROPN
admet-1437	131	138	.	.	PROPN
admet-1437	131	139	figure	figure	NOUN
admet-1437	131	140	1	1	NUM
admet-1437	131	141	schematically	schematically	NOUN
admet-1437	131	142	outlines	outline	VERB
admet-1437	131	143	the	the	DET
admet-1437	131	144	workflow	workflow	NOUN
admet-1437	131	145	of	of	ADP
admet-1437	131	146	the	the	DET
admet-1437	131	147	established	establish	VERB
admet-1437	131	148	numerical	numerical	ADJ
admet-1437	131	149	model	model	NOUN
admet-1437	131	150	for	for	ADP
admet-1437	131	151	the	the	DET
admet-1437	131	152	calculation	calculation	NOUN
admet-1437	131	153	of	of	ADP
admet-1437	131	154	the	the	DET
admet-1437	131	155	dissolution	dissolution	NOUN
admet-1437	131	156	of	of	ADP
admet-1437	131	157	small	small	ADJ
admet-1437	131	158	particles	particle	NOUN
admet-1437	131	159	,	,	PUNCT
admet-1437	131	160	specifically	specifically	ADV
admet-1437	131	161	for	for	ADP
admet-1437	131	162	size	size	NOUN
admet-1437	131	163	distributions	distribution	NOUN
admet-1437	131	164	with	with	ADP
admet-1437	131	165	particles	particle	NOUN
admet-1437	131	166	x	x	SYM
admet-1437	131	167	≪	≪	ADJ
admet-1437	131	168	1	1	NUM
admet-1437	131	169	µm	µm	NOUN
admet-1437	131	170	.	.	PUNCT
admet-1437	132	1	besides	besides	SCONJ
admet-1437	132	2	the	the	DET
admet-1437	132	3	input	input	NOUN
admet-1437	132	4	parameters	parameter	NOUN
admet-1437	132	5	needed	need	VERB
admet-1437	132	6	for	for	ADP
admet-1437	132	7	the	the	DET
admet-1437	132	8	equations	equation	NOUN
admet-1437	132	9	(	(	PUNCT
admet-1437	132	10	1	1	NUM
admet-1437	132	11	)	)	PUNCT
admet-1437	132	12	,	,	PUNCT
admet-1437	132	13	(	(	PUNCT
admet-1437	132	14	2	2	X
admet-1437	132	15	)	)	PUNCT
admet-1437	132	16	and	and	CCONJ
admet-1437	132	17	(	(	PUNCT
admet-1437	132	18	4	4	NUM
admet-1437	132	19	)	)	PUNCT
admet-1437	132	20	,	,	PUNCT
admet-1437	132	21	as	as	ADV
admet-1437	132	22	well	well	ADV
admet-1437	132	23	as	as	ADP
admet-1437	132	24	the	the	DET
admet-1437	132	25	particle	particle	NOUN
admet-1437	132	26	size	size	NOUN
admet-1437	132	27	distribution	distribution	NOUN
admet-1437	132	28	data	datum	NOUN
admet-1437	132	29	,	,	PUNCT
admet-1437	132	30	information	information	NOUN
admet-1437	132	31	about	about	ADP
admet-1437	132	32	the	the	DET
admet-1437	132	33	dissolution	dissolution	PROPN
admet-1437	132	34	scenario	scenario	NOUN
admet-1437	132	35	,	,	PUNCT
admet-1437	132	36	i.e.	i.e.	X
admet-1437	132	37	,	,	PUNCT
admet-1437	132	38	the	the	DET
admet-1437	132	39	amount	amount	NOUN
admet-1437	132	40	of	of	ADP
admet-1437	132	41	solid	solid	ADJ
admet-1437	132	42	drug	drug	NOUN
admet-1437	132	43	and	and	CCONJ
admet-1437	132	44	amount	amount	NOUN
admet-1437	132	45	of	of	ADP
admet-1437	132	46	dissolution	dissolution	NOUN
admet-1437	132	47	media	medium	NOUN
admet-1437	132	48	,	,	PUNCT
admet-1437	132	49	is	be	AUX
admet-1437	132	50	required	require	VERB
admet-1437	132	51	as	as	ADP
admet-1437	132	52	input	input	NOUN
admet-1437	132	53	parameters	parameter	NOUN
admet-1437	132	54	for	for	ADP
admet-1437	132	55	the	the	DET
admet-1437	132	56	calculation	calculation	NOUN
admet-1437	132	57	.	.	PUNCT
admet-1437	133	1	thus	thus	ADV
admet-1437	133	2	the	the	DET
admet-1437	133	3	model	model	NOUN
admet-1437	133	4	offers	offer	VERB
admet-1437	133	5	the	the	DET
admet-1437	133	6	possibility	possibility	NOUN
admet-1437	133	7	to	to	PART
admet-1437	133	8	flexibly	flexibly	ADV
admet-1437	133	9	adjust	adjust	VERB
admet-1437	133	10	the	the	DET
admet-1437	133	11	calculated	calculated	ADJ
admet-1437	133	12	scenario	scenario	NOUN
admet-1437	133	13	to	to	ADP
admet-1437	133	14	any	any	DET
admet-1437	133	15	application	application	NOUN
admet-1437	133	16	of	of	ADP
admet-1437	133	17	interest	interest	NOUN
admet-1437	133	18	,	,	PUNCT
admet-1437	133	19	i.e.	i.e.	X
admet-1437	133	20	,	,	PUNCT
admet-1437	133	21	from	from	ADP
admet-1437	133	22	sink	sink	NOUN
admet-1437	133	23	to	to	ADP
admet-1437	133	24	non	non	ADJ
admet-1437	133	25	-	-	ADJ
admet-1437	133	26	sink	sink	ADJ
admet-1437	133	27	conditions	condition	NOUN
admet-1437	133	28	.	.	PUNCT
admet-1437	134	1	in	in	ADP
admet-1437	134	2	this	this	DET
admet-1437	134	3	context	context	NOUN
admet-1437	134	4	,	,	PUNCT
admet-1437	134	5	the	the	DET
admet-1437	134	6	dose	dose	NOUN
admet-1437	134	7	number	number	NOUN
admet-1437	134	8	(	(	PUNCT
admet-1437	134	9	do	do	AUX
admet-1437	134	10	)	)	PUNCT
admet-1437	134	11	is	be	AUX
admet-1437	134	12	a	a	DET
admet-1437	134	13	functional	functional	ADJ
admet-1437	134	14	parameter	parameter	NOUN
admet-1437	134	15	to	to	PART
admet-1437	134	16	simply	simply	ADV
admet-1437	134	17	describe	describe	VERB
admet-1437	134	18	the	the	DET
admet-1437	134	19	ratio	ratio	NOUN
admet-1437	134	20	of	of	ADP
admet-1437	134	21	available	available	ADJ
admet-1437	134	22	solid	solid	ADJ
admet-1437	134	23	drug	drug	NOUN
admet-1437	134	24	to	to	ADP
admet-1437	134	25	the	the	DET
admet-1437	134	26	thermodynamically	thermodynamically	ADV
admet-1437	134	27	soluble	soluble	ADJ
admet-1437	134	28	amount	amount	NOUN
admet-1437	134	29	in	in	ADP
admet-1437	134	30	a	a	DET
admet-1437	134	31	certain	certain	ADJ
admet-1437	134	32	amount	amount	NOUN
admet-1437	134	33	of	of	ADP
admet-1437	134	34	dissolution	dissolution	ADJ
admet-1437	134	35	media	medium	NOUN
admet-1437	134	36	.	.	PUNCT
admet-1437	135	1	do	do	AUX
admet-1437	135	2	was	be	AUX
admet-1437	135	3	introduced	introduce	VERB
admet-1437	135	4	by	by	ADP
admet-1437	135	5	amidon	amidon	PROPN
admet-1437	135	6	et	et	PROPN
admet-1437	135	7	al	al	PROPN
admet-1437	135	8	.	.	PROPN
admet-1437	136	1	in	in	ADP
admet-1437	136	2	the	the	DET
admet-1437	136	3	1990s	1990	NOUN
admet-1437	136	4	[	[	X
admet-1437	136	5	73,74	73,74	NOUN
admet-1437	136	6	]	]	PUNCT
admet-1437	136	7	and	and	CCONJ
admet-1437	136	8	the	the	DET
admet-1437	136	9	parameter	parameter	NOUN
admet-1437	136	10	has	have	AUX
admet-1437	136	11	become	become	VERB
admet-1437	136	12	a	a	DET
admet-1437	136	13	standard	standard	NOUN
admet-1437	136	14	to	to	PART
admet-1437	136	15	assess	assess	VERB
admet-1437	136	16	and	and	CCONJ
admet-1437	136	17	classify	classify	VERB
admet-1437	136	18	the	the	DET
admet-1437	136	19	risk	risk	NOUN
admet-1437	136	20	for	for	ADP
admet-1437	136	21	oral	oral	ADJ
admet-1437	136	22	absorption	absorption	NOUN
admet-1437	136	23	in	in	ADP
admet-1437	136	24	terms	term	NOUN
admet-1437	136	25	of	of	ADP
admet-1437	136	26	dissolution	dissolution	NOUN
admet-1437	136	27	[	[	X
admet-1437	136	28	75	75	NUM
admet-1437	136	29	-	-	SYM
admet-1437	136	30	80	80	NUM
admet-1437	136	31	]	]	PUNCT
admet-1437	136	32	.	.	PUNCT
admet-1437	137	1	𝐷o	𝐷o	NOUN
admet-1437	137	2	=	=	PUNCT
admet-1437	137	3	𝑚	𝑚	PROPN
admet-1437	137	4	𝑠0∙𝑉l	𝑠0∙𝑉l	NOUN
admet-1437	137	5	(	(	PUNCT
admet-1437	137	6	5	5	NUM
admet-1437	137	7	)	)	PUNCT
admet-1437	137	8	where	where	SCONJ
admet-1437	137	9	m	m	NOUN
admet-1437	137	10	is	be	AUX
admet-1437	137	11	the	the	DET
admet-1437	137	12	amount	amount	NOUN
admet-1437	137	13	of	of	ADP
admet-1437	137	14	solid	solid	ADJ
admet-1437	137	15	drug	drug	NOUN
admet-1437	137	16	,	,	PUNCT
admet-1437	137	17	s0	s0	PROPN
admet-1437	137	18	the	the	DET
admet-1437	137	19	thermodynamic	thermodynamic	ADJ
admet-1437	137	20	solubility	solubility	NOUN
admet-1437	137	21	for	for	ADP
admet-1437	137	22	large	large	ADJ
admet-1437	137	23	particles	particle	NOUN
admet-1437	138	1	𝑥	𝑥	PROPN
admet-1437	138	2	≫	≫	NOUN
admet-1437	138	3	1	1	NUM
admet-1437	138	4	µm	µm	NOUN
admet-1437	138	5	in	in	ADP
admet-1437	138	6	the	the	DET
admet-1437	138	7	related	relate	VERB
admet-1437	138	8	dissolution	dissolution	NOUN
admet-1437	138	9	medium	medium	NOUN
admet-1437	138	10	with	with	ADP
admet-1437	138	11	volume	volume	NOUN
admet-1437	138	12	vl	vl	PROPN
admet-1437	138	13	.	.	PUNCT
admet-1437	139	1	the	the	DET
admet-1437	139	2	numerical	numerical	ADJ
admet-1437	139	3	calculation	calculation	NOUN
admet-1437	139	4	is	be	AUX
admet-1437	139	5	carried	carry	VERB
admet-1437	139	6	out	out	ADP
admet-1437	139	7	iteratively	iteratively	ADV
admet-1437	139	8	for	for	ADP
admet-1437	139	9	each	each	DET
admet-1437	139	10	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	NOUN
admet-1437	139	11	bonhoeffer	bonhoeffer	PROPN
admet-1437	139	12	et	et	PROPN
admet-1437	139	13	al	al	PROPN
admet-1437	139	14	.	.	PROPN
admet-1437	139	15	admet	admet	PROPN
admet-1437	139	16	&	&	CCONJ
admet-1437	139	17	dmpk	dmpk	PROPN
admet-1437	139	18	10(4	10(4	NUM
admet-1437	139	19	)	)	PUNCT
admet-1437	139	20	(	(	PUNCT
admet-1437	139	21	2022	2022	NUM
admet-1437	139	22	)	)	PUNCT
admet-1437	139	23	253	253	NUM
admet-1437	139	24	-	-	SYM
admet-1437	139	25	287	287	NUM
admet-1437	139	26	260	260	NUM
admet-1437	139	27	particle	particle	NOUN
admet-1437	139	28	class	class	NOUN
admet-1437	139	29	𝑖	𝑖	PROPN
admet-1437	139	30	,	,	PUNCT
admet-1437	139	31	with	with	ADP
admet-1437	139	32	the	the	DET
admet-1437	139	33	number	number	NOUN
admet-1437	139	34	of	of	ADP
admet-1437	139	35	iterations	iteration	NOUN
admet-1437	139	36	𝑗	𝑗	VERB
admet-1437	139	37	and	and	CCONJ
admet-1437	139	38	the	the	DET
admet-1437	139	39	time	time	NOUN
admet-1437	139	40	step	step	NOUN
admet-1437	139	41	∆𝑡.	∆𝑡.	PROPN
admet-1437	139	42	as	as	ADP
admet-1437	139	43	the	the	DET
admet-1437	139	44	first	first	ADJ
admet-1437	139	45	step	step	NOUN
admet-1437	139	46	in	in	ADP
admet-1437	139	47	each	each	DET
admet-1437	139	48	iteration	iteration	NOUN
admet-1437	139	49	,	,	PUNCT
admet-1437	139	50	the	the	DET
admet-1437	139	51	mass	mass	ADJ
admet-1437	139	52	,	,	PUNCT
admet-1437	139	53	volume	volume	NOUN
admet-1437	139	54	,	,	PUNCT
admet-1437	139	55	and	and	CCONJ
admet-1437	139	56	surface	surface	NOUN
admet-1437	139	57	area	area	NOUN
admet-1437	139	58	are	be	AUX
admet-1437	139	59	calculated	calculate	VERB
admet-1437	139	60	for	for	ADP
admet-1437	139	61	each	each	DET
admet-1437	139	62	particle	particle	NOUN
admet-1437	139	63	class	class	NOUN
admet-1437	139	64	.	.	PUNCT
admet-1437	140	1	as	as	ADV
admet-1437	140	2	long	long	ADV
admet-1437	140	3	as	as	SCONJ
admet-1437	140	4	the	the	DET
admet-1437	140	5	mass	mass	NOUN
admet-1437	140	6	of	of	ADP
admet-1437	140	7	a	a	DET
admet-1437	140	8	particle	particle	NOUN
admet-1437	140	9	class	class	NOUN
admet-1437	140	10	is	be	AUX
admet-1437	140	11	𝑚𝑖,𝑗	𝑚𝑖,𝑗	PUNCT
admet-1437	140	12	>	>	X
admet-1437	140	13	0	0	NUM
admet-1437	140	14	,	,	PUNCT
admet-1437	140	15	the	the	DET
admet-1437	140	16	apparent	apparent	ADJ
admet-1437	140	17	solubility	solubility	NOUN
admet-1437	140	18	for	for	ADP
admet-1437	140	19	each	each	DET
admet-1437	140	20	class	class	NOUN
admet-1437	140	21	𝑠𝑎𝑝𝑝,𝑖,𝑗	𝑠𝑎𝑝𝑝,𝑖,𝑗	PROPN
admet-1437	140	22	is	be	AUX
admet-1437	140	23	calculated	calculate	VERB
admet-1437	140	24	based	base	VERB
admet-1437	140	25	on	on	ADP
admet-1437	140	26	its	its	PRON
admet-1437	140	27	particle	particle	NOUN
admet-1437	140	28	size	size	NOUN
admet-1437	140	29	𝑥𝑖,𝑗	𝑥𝑖,𝑗	NOUN
admet-1437	140	30	using	use	VERB
admet-1437	140	31	the	the	DET
admet-1437	140	32	ostwald	ostwald	NOUN
admet-1437	140	33	-	-	PUNCT
admet-1437	140	34	freundlich	freundlich	ADJ
admet-1437	140	35	equation	equation	NOUN
admet-1437	140	36	.	.	PUNCT
admet-1437	141	1	if	if	SCONJ
admet-1437	141	2	the	the	DET
admet-1437	141	3	apparent	apparent	ADJ
admet-1437	141	4	solubility	solubility	NOUN
admet-1437	141	5	is	be	AUX
admet-1437	141	6	higher	high	ADJ
admet-1437	141	7	than	than	ADP
admet-1437	141	8	the	the	DET
admet-1437	141	9	concentration	concentration	NOUN
admet-1437	141	10	in	in	ADP
admet-1437	141	11	the	the	DET
admet-1437	141	12	dissolution	dissolution	PROPN
admet-1437	141	13	medium	medium	PROPN
admet-1437	141	14	𝑠app,𝑖,𝑗	𝑠app,𝑖,𝑗	PROPN
admet-1437	141	15	>	>	X
admet-1437	141	16	𝑐𝑙,𝑗	𝑐𝑙,𝑗	PROPN
admet-1437	141	17	,	,	PUNCT
admet-1437	141	18	the	the	DET
admet-1437	141	19	particles	particle	NOUN
admet-1437	141	20	of	of	ADP
admet-1437	141	21	that	that	DET
admet-1437	141	22	class	class	NOUN
admet-1437	141	23	can	can	AUX
admet-1437	141	24	further	far	ADV
admet-1437	141	25	dissolve	dissolve	VERB
admet-1437	141	26	,	,	PUNCT
admet-1437	141	27	and	and	CCONJ
admet-1437	141	28	the	the	DET
admet-1437	141	29	dissolution	dissolution	NOUN
admet-1437	141	30	rate	rate	NOUN
admet-1437	141	31	is	be	AUX
admet-1437	141	32	calculated	calculate	VERB
admet-1437	141	33	using	use	VERB
admet-1437	141	34	the	the	DET
admet-1437	141	35	noyes	noyes	PROPN
admet-1437	141	36	-	-	PUNCT
admet-1437	141	37	whitney	whitney	PROPN
admet-1437	141	38	/	/	SYM
admet-1437	141	39	nernst	nernst	PROPN
admet-1437	141	40	-	-	PUNCT
admet-1437	141	41	brunner	brunner	NOUN
admet-1437	141	42	equation	equation	NOUN
admet-1437	141	43	.	.	PUNCT
admet-1437	142	1	with	with	ADP
admet-1437	142	2	the	the	DET
admet-1437	142	3	selected	select	VERB
admet-1437	142	4	time	time	NOUN
admet-1437	142	5	step	step	NOUN
admet-1437	142	6	∆𝑡	∆𝑡	PROPN
admet-1437	142	7	,	,	PUNCT
admet-1437	142	8	the	the	DET
admet-1437	142	9	new	new	ADJ
admet-1437	142	10	particle	particle	NOUN
admet-1437	142	11	size	size	NOUN
admet-1437	142	12	for	for	ADP
admet-1437	142	13	each	each	DET
admet-1437	142	14	class	class	NOUN
admet-1437	142	15	for	for	ADP
admet-1437	142	16	the	the	DET
admet-1437	142	17	next	next	ADJ
admet-1437	142	18	iteration	iteration	NOUN
admet-1437	142	19	𝑥𝑖,𝑗+1	𝑥𝑖,𝑗+1	NOUN
admet-1437	142	20	is	be	AUX
admet-1437	142	21	determined	determine	VERB
admet-1437	142	22	as	as	ADV
admet-1437	142	23	well	well	ADV
admet-1437	142	24	as	as	ADP
admet-1437	142	25	the	the	DET
admet-1437	142	26	amount	amount	NOUN
admet-1437	142	27	of	of	ADP
admet-1437	142	28	dissolved	dissolve	VERB
admet-1437	142	29	compound	compound	NOUN
admet-1437	142	30	for	for	ADP
admet-1437	142	31	each	each	DET
admet-1437	142	32	class	class	NOUN
admet-1437	142	33	∆𝑚𝑖,𝑗.	∆𝑚𝑖,𝑗.	PROPN
admet-1437	142	34	consequently	consequently	ADV
admet-1437	142	35	,	,	PUNCT
admet-1437	142	36	the	the	DET
admet-1437	142	37	number	number	NOUN
admet-1437	142	38	of	of	ADP
admet-1437	142	39	particles	particle	NOUN
admet-1437	142	40	per	per	ADP
admet-1437	142	41	class	class	NOUN
admet-1437	142	42	is	be	AUX
admet-1437	142	43	constant	constant	ADJ
admet-1437	142	44	and	and	CCONJ
admet-1437	142	45	each	each	DET
admet-1437	142	46	particle	particle	NOUN
admet-1437	142	47	remains	remain	VERB
admet-1437	142	48	in	in	ADP
admet-1437	142	49	its	its	PRON
admet-1437	142	50	initial	initial	ADJ
admet-1437	142	51	class	class	NOUN
admet-1437	142	52	,	,	PUNCT
admet-1437	142	53	however	however	ADV
admet-1437	142	54	,	,	PUNCT
admet-1437	142	55	the	the	DET
admet-1437	142	56	class	class	NOUN
admet-1437	142	57	’s	’s	PART
admet-1437	142	58	particle	particle	NOUN
admet-1437	142	59	size	size	NOUN
admet-1437	142	60	is	be	AUX
admet-1437	142	61	decreasing	decrease	VERB
admet-1437	142	62	.	.	PUNCT
admet-1437	143	1	the	the	DET
admet-1437	143	2	sum	sum	NOUN
admet-1437	143	3	of	of	ADP
admet-1437	143	4	dissolved	dissolve	VERB
admet-1437	143	5	drug	drug	NOUN
admet-1437	143	6	compound	compound	NOUN
admet-1437	143	7	from	from	ADP
admet-1437	143	8	all	all	DET
admet-1437	143	9	classes	class	NOUN
admet-1437	143	10	∆𝑚𝑗	∆𝑚𝑗	ADV
admet-1437	143	11	is	be	AUX
admet-1437	143	12	added	add	VERB
admet-1437	143	13	to	to	ADP
admet-1437	143	14	the	the	DET
admet-1437	143	15	concentration	concentration	NOUN
admet-1437	143	16	𝑐𝑙,𝑗	𝑐𝑙,𝑗	PUNCT
admet-1437	143	17	resulting	result	VERB
admet-1437	143	18	in	in	ADP
admet-1437	143	19	the	the	DET
admet-1437	143	20	new	new	ADJ
admet-1437	143	21	concentration	concentration	NOUN
admet-1437	143	22	𝑐𝑙,𝑗+1	𝑐𝑙,𝑗+1	NOUN
admet-1437	143	23	.	.	PUNCT
admet-1437	144	1	finally	finally	ADV
admet-1437	144	2	,	,	PUNCT
admet-1437	144	3	the	the	DET
admet-1437	144	4	time	time	NOUN
admet-1437	144	5	for	for	ADP
admet-1437	144	6	the	the	DET
admet-1437	144	7	next	next	ADJ
admet-1437	144	8	iteration	iteration	NOUN
admet-1437	144	9	step	step	NOUN
admet-1437	144	10	is	be	AUX
admet-1437	144	11	determined	determine	VERB
admet-1437	144	12	𝑡𝑗+1	𝑡𝑗+1	NUM
admet-1437	144	13	=	=	SYM
admet-1437	144	14	𝑡𝑗	𝑡𝑗	PROPN
admet-1437	144	15	+	+	NUM
admet-1437	144	16	∆𝑡	∆𝑡	PROPN
admet-1437	144	17	.	.	PUNCT
admet-1437	145	1	the	the	DET
admet-1437	145	2	calculation	calculation	NOUN
admet-1437	145	3	cycle	cycle	NOUN
admet-1437	145	4	is	be	AUX
admet-1437	145	5	repeated	repeat	VERB
admet-1437	145	6	as	as	ADV
admet-1437	145	7	long	long	ADV
admet-1437	145	8	as	as	SCONJ
admet-1437	145	9	there	there	PRON
admet-1437	145	10	is	be	VERB
admet-1437	145	11	a	a	DET
admet-1437	145	12	particle	particle	NOUN
admet-1437	145	13	class	class	NOUN
admet-1437	145	14	remaining	remain	VERB
admet-1437	145	15	for	for	ADP
admet-1437	145	16	which	which	PRON
admet-1437	145	17	𝑠𝑎𝑝𝑝,𝑖,𝑗	𝑠𝑎𝑝𝑝,𝑖,𝑗	PROPN
admet-1437	145	18	>	>	X
admet-1437	145	19	𝑐𝑙,𝑗	𝑐𝑙,𝑗	X
admet-1437	145	20	is	be	AUX
admet-1437	145	21	true	true	ADJ
admet-1437	145	22	or	or	CCONJ
admet-1437	145	23	until	until	SCONJ
admet-1437	145	24	all	all	DET
admet-1437	145	25	material	material	NOUN
admet-1437	145	26	has	have	AUX
admet-1437	145	27	been	be	AUX
admet-1437	145	28	dissolved	dissolve	VERB
admet-1437	145	29	.	.	PUNCT
admet-1437	146	1	at	at	ADP
admet-1437	146	2	the	the	DET
admet-1437	146	3	end	end	NOUN
admet-1437	146	4	of	of	ADP
admet-1437	146	5	the	the	DET
admet-1437	146	6	calculation	calculation	NOUN
admet-1437	146	7	,	,	PUNCT
admet-1437	146	8	the	the	DET
admet-1437	146	9	system	system	NOUN
admet-1437	146	10	is	be	AUX
admet-1437	146	11	considered	consider	VERB
admet-1437	146	12	to	to	PART
admet-1437	146	13	be	be	AUX
admet-1437	146	14	in	in	ADP
admet-1437	146	15	equilibrium	equilibrium	NOUN
admet-1437	146	16	.	.	PUNCT
admet-1437	147	1	for	for	ADP
admet-1437	147	2	simplification	simplification	NOUN
admet-1437	147	3	,	,	PUNCT
admet-1437	147	4	throughout	throughout	ADP
admet-1437	147	5	this	this	DET
admet-1437	147	6	manuscript	manuscript	NOUN
admet-1437	147	7	,	,	PUNCT
admet-1437	147	8	the	the	DET
admet-1437	147	9	term	term	NOUN
admet-1437	147	10	“	"	PUNCT
admet-1437	147	11	thermodynamic	thermodynamic	ADJ
admet-1437	147	12	solubility	solubility	NOUN
admet-1437	147	13	”	"	PUNCT
admet-1437	147	14	is	be	AUX
admet-1437	147	15	used	use	VERB
admet-1437	147	16	to	to	PART
admet-1437	147	17	represent	represent	VERB
admet-1437	147	18	the	the	DET
admet-1437	147	19	solubility	solubility	NOUN
admet-1437	147	20	of	of	ADP
admet-1437	147	21	coarse	coarse	ADJ
admet-1437	147	22	particles	particle	NOUN
admet-1437	147	23	with	with	ADP
admet-1437	147	24	a	a	DET
admet-1437	147	25	size	size	NOUN
admet-1437	147	26	x	x	X
admet-1437	147	27	>	>	X
admet-1437	147	28	>	>	X
admet-1437	147	29	1	1	NUM
admet-1437	147	30	µm	µm	NOUN
admet-1437	147	31	,	,	PUNCT
admet-1437	147	32	and	and	CCONJ
admet-1437	147	33	the	the	DET
admet-1437	147	34	term	term	NOUN
admet-1437	147	35	“	"	PUNCT
admet-1437	147	36	apparent	apparent	ADJ
admet-1437	147	37	solubility	solubility	NOUN
admet-1437	147	38	”	"	PUNCT
admet-1437	147	39	is	be	AUX
admet-1437	147	40	used	use	VERB
admet-1437	147	41	interchangeably	interchangeably	ADV
admet-1437	147	42	to	to	ADP
admet-1437	147	43	“	"	PUNCT
admet-1437	147	44	resulting	result	VERB
admet-1437	147	45	concentration	concentration	NOUN
admet-1437	147	46	at	at	ADP
admet-1437	147	47	equilibrium	equilibrium	NOUN
admet-1437	147	48	”	"	PUNCT
admet-1437	147	49	,	,	PUNCT
admet-1437	147	50	if	if	SCONJ
admet-1437	147	51	supersaturation	supersaturation	NOUN
admet-1437	147	52	has	have	AUX
admet-1437	147	53	been	be	AUX
admet-1437	147	54	reached	reach	VERB
admet-1437	147	55	.	.	PUNCT
admet-1437	148	1	table	table	NOUN
admet-1437	148	2	1	1	NUM
admet-1437	148	3	summarizes	summarize	VERB
admet-1437	148	4	the	the	DET
admet-1437	148	5	input	input	NOUN
admet-1437	148	6	parameters	parameter	NOUN
admet-1437	148	7	used	use	VERB
admet-1437	148	8	for	for	ADP
admet-1437	148	9	the	the	DET
admet-1437	148	10	numerical	numerical	ADJ
admet-1437	148	11	model	model	PROPN
admet-1437	148	12	.	.	PUNCT
admet-1437	149	1	the	the	DET
admet-1437	149	2	calculation	calculation	NOUN
admet-1437	149	3	was	be	AUX
admet-1437	149	4	programmed	program	VERB
admet-1437	149	5	in	in	ADP
admet-1437	149	6	microsoft	microsoft	PROPN
admet-1437	149	7	excel	excel	VERB
admet-1437	149	8	2016	2016	NUM
admet-1437	149	9	with	with	ADP
admet-1437	149	10	microsoft	microsoft	PROPN
admet-1437	149	11	visual	visual	PROPN
admet-1437	149	12	basic	basic	PROPN
admet-1437	149	13	for	for	ADP
admet-1437	149	14	applications	application	NOUN
admet-1437	149	15	7.1	7.1	NUM
admet-1437	149	16	.	.	PUNCT
admet-1437	150	1	table	table	NOUN
admet-1437	150	2	1	1	NUM
admet-1437	150	3	.	.	PUNCT
admet-1437	151	1	input	input	NOUN
admet-1437	151	2	parameters	parameter	NOUN
admet-1437	151	3	for	for	ADP
admet-1437	151	4	the	the	DET
admet-1437	151	5	established	establish	VERB
admet-1437	151	6	numerical	numerical	ADJ
admet-1437	151	7	model	model	PROPN
admet-1437	151	8	.	.	PUNCT
admet-1437	152	1	parameter	parameter	PROPN
admet-1437	152	2	value	value	NOUN
admet-1437	152	3	unit	unit	NOUN
admet-1437	152	4	drug	drug	PROPN
admet-1437	152	5	molar	molar	PROPN
admet-1437	152	6	volume	volume	NOUN
admet-1437	152	7	,	,	PUNCT
admet-1437	152	8	vm	vm	PROPN
admet-1437	152	9	3.72·10	3.72·10	NUM
admet-1437	152	10	-	-	SYM
admet-1437	152	11	4	4	NUM
admet-1437	152	12	m3	m3	PROPN
admet-1437	152	13	/	/	SYM
admet-1437	152	14	mol	mol	ADP
admet-1437	152	15	dynamic	dynamic	ADJ
admet-1437	152	16	viscosity	viscosity	NOUN
admet-1437	152	17	of	of	ADP
admet-1437	152	18	dissolution	dissolution	NOUN
admet-1437	152	19	media	medium	NOUN
admet-1437	152	20	,	,	PUNCT
admet-1437	152	21	η	η	PROPN
admet-1437	152	22	1	1	NUM
admet-1437	152	23	mpa	mpa	PROPN
admet-1437	152	24	s	s	PART
admet-1437	152	25	interfacial	interfacial	ADJ
admet-1437	152	26	energy	energy	NOUN
admet-1437	152	27	between	between	ADP
admet-1437	152	28	solid	solid	ADJ
admet-1437	152	29	and	and	CCONJ
admet-1437	152	30	liquid	liquid	ADJ
admet-1437	152	31	,	,	PUNCT
admet-1437	152	32	σsl	σsl	VERB
admet-1437	152	33	30	30	NUM
admet-1437	152	34	mj	mj	NOUN
admet-1437	152	35	/	/	SYM
admet-1437	152	36	m2	m2	PROPN
admet-1437	152	37	solid	solid	ADJ
admet-1437	152	38	drug	drug	NOUN
admet-1437	152	39	density	density	NOUN
admet-1437	152	40	,	,	PUNCT
admet-1437	152	41	ρ	ρ	PROPN
admet-1437	152	42	1364	1364	NUM
admet-1437	152	43	kg	kg	NOUN
admet-1437	152	44	/	/	SYM
admet-1437	152	45	m3	m3	PROPN
admet-1437	152	46	thermodynamic	thermodynamic	ADJ
admet-1437	152	47	solubility	solubility	PROPN
admet-1437	152	48	,	,	PUNCT
admet-1437	152	49	s0,ph3	s0,ph3	AUX
admet-1437	152	50	28	28	NUM
admet-1437	152	51	mg	mg	NUM
admet-1437	152	52	/	/	SYM
admet-1437	152	53	l	l	NOUN
admet-1437	152	54	the	the	DET
admet-1437	152	55	decrease	decrease	NOUN
admet-1437	152	56	of	of	ADP
admet-1437	152	57	the	the	DET
admet-1437	152	58	particle	particle	NOUN
admet-1437	152	59	size	size	NOUN
admet-1437	152	60	of	of	ADP
admet-1437	152	61	the	the	DET
admet-1437	152	62	individual	individual	ADJ
admet-1437	152	63	classes	class	NOUN
admet-1437	152	64	and	and	CCONJ
admet-1437	152	65	the	the	DET
admet-1437	152	66	change	change	NOUN
admet-1437	152	67	of	of	ADP
admet-1437	152	68	the	the	DET
admet-1437	152	69	particle	particle	NOUN
admet-1437	152	70	size	size	NOUN
admet-1437	152	71	distribution	distribution	NOUN
admet-1437	152	72	as	as	ADP
admet-1437	152	73	a	a	DET
admet-1437	152	74	function	function	NOUN
admet-1437	152	75	of	of	ADP
admet-1437	152	76	time	time	NOUN
admet-1437	152	77	is	be	AUX
admet-1437	152	78	obtained	obtain	VERB
admet-1437	152	79	as	as	ADP
admet-1437	152	80	output	output	NOUN
admet-1437	152	81	from	from	ADP
admet-1437	152	82	the	the	DET
admet-1437	152	83	numerical	numerical	ADJ
admet-1437	152	84	model	model	NOUN
admet-1437	152	85	.	.	PUNCT
admet-1437	153	1	in	in	ADP
admet-1437	153	2	addition	addition	NOUN
admet-1437	153	3	,	,	PUNCT
admet-1437	153	4	for	for	ADP
admet-1437	153	5	cases	case	NOUN
admet-1437	153	6	where	where	SCONJ
admet-1437	153	7	do	do	VERB
admet-1437	153	8	>	>	X
admet-1437	153	9	1	1	NUM
admet-1437	153	10	,	,	PUNCT
admet-1437	153	11	the	the	DET
admet-1437	153	12	remaining	remain	VERB
admet-1437	153	13	mass	mass	NOUN
admet-1437	153	14	fraction	fraction	NOUN
admet-1437	153	15	of	of	ADP
admet-1437	153	16	the	the	DET
admet-1437	153	17	solid	solid	ADJ
admet-1437	153	18	drug	drug	NOUN
admet-1437	153	19	and	and	CCONJ
admet-1437	153	20	its	its	PRON
admet-1437	153	21	final	final	ADJ
admet-1437	153	22	particle	particle	NOUN
admet-1437	153	23	size	size	NOUN
admet-1437	153	24	distribution	distribution	NOUN
admet-1437	153	25	is	be	AUX
admet-1437	153	26	captured	capture	VERB
admet-1437	153	27	,	,	PUNCT
admet-1437	153	28	if	if	SCONJ
admet-1437	153	29	applicable	applicable	ADJ
admet-1437	153	30	.	.	PUNCT
admet-1437	154	1	similarly	similarly	ADV
admet-1437	154	2	,	,	PUNCT
admet-1437	154	3	the	the	DET
admet-1437	154	4	concentration	concentration	NOUN
admet-1437	154	5	increase	increase	NOUN
admet-1437	154	6	in	in	ADP
admet-1437	154	7	the	the	DET
admet-1437	154	8	dissolution	dissolution	NOUN
admet-1437	154	9	medium	medium	NOUN
admet-1437	154	10	as	as	ADP
admet-1437	154	11	a	a	DET
admet-1437	154	12	function	function	NOUN
admet-1437	154	13	of	of	ADP
admet-1437	154	14	time	time	NOUN
admet-1437	154	15	as	as	ADV
admet-1437	154	16	well	well	ADV
admet-1437	154	17	as	as	ADP
admet-1437	154	18	the	the	DET
admet-1437	154	19	equilibrium	equilibrium	NOUN
admet-1437	154	20	concentration	concentration	NOUN
admet-1437	154	21	in	in	ADP
admet-1437	154	22	the	the	DET
admet-1437	154	23	dissolution	dissolution	NOUN
admet-1437	154	24	medium	medium	NOUN
admet-1437	154	25	,	,	PUNCT
admet-1437	154	26	which	which	PRON
admet-1437	154	27	corresponds	correspond	VERB
admet-1437	154	28	to	to	ADP
admet-1437	154	29	the	the	DET
admet-1437	154	30	achieved	achieve	VERB
admet-1437	154	31	apparent	apparent	ADJ
admet-1437	154	32	solubility	solubility	NOUN
admet-1437	154	33	for	for	ADP
admet-1437	154	34	cases	case	NOUN
admet-1437	154	35	where	where	SCONJ
admet-1437	154	36	do	do	VERB
admet-1437	154	37	>	>	X
admet-1437	154	38	1	1	NUM
admet-1437	154	39	,	,	PUNCT
admet-1437	154	40	are	be	AUX
admet-1437	154	41	obtained	obtain	VERB
admet-1437	154	42	.	.	PUNCT
admet-1437	155	1	results	result	NOUN
admet-1437	155	2	and	and	CCONJ
admet-1437	155	3	discussion	discussion	NOUN
admet-1437	155	4	particle	particle	NOUN
admet-1437	155	5	size	size	NOUN
admet-1437	155	6	characterization	characterization	NOUN
admet-1437	155	7	of	of	ADP
admet-1437	155	8	nanocrystals	nanocrystal	NOUN
admet-1437	155	9	the	the	DET
admet-1437	155	10	coarse	coarse	ADJ
admet-1437	155	11	crystal	crystal	NOUN
admet-1437	155	12	and	and	CCONJ
admet-1437	155	13	the	the	DET
admet-1437	155	14	manufactured	manufacture	VERB
admet-1437	155	15	nanocrystal	nanocrystal	ADJ
admet-1437	155	16	particle	particle	NOUN
admet-1437	155	17	size	size	NOUN
admet-1437	155	18	distributions	distribution	NOUN
admet-1437	155	19	as	as	SCONJ
admet-1437	155	20	determined	determine	VERB
admet-1437	155	21	by	by	ADP
admet-1437	155	22	laser	laser	NOUN
admet-1437	155	23	light	light	ADJ
admet-1437	155	24	diffraction	diffraction	NOUN
admet-1437	155	25	(	(	PUNCT
admet-1437	155	26	lld	lld	PROPN
admet-1437	155	27	)	)	PUNCT
admet-1437	155	28	and	and	CCONJ
admet-1437	155	29	photon	photon	NOUN
admet-1437	155	30	correlation	correlation	NOUN
admet-1437	155	31	spectroscopy	spectroscopy	NOUN
admet-1437	155	32	(	(	PUNCT
admet-1437	155	33	pcs	pc	NOUN
admet-1437	155	34	)	)	PUNCT
admet-1437	155	35	approximated	approximate	VERB
admet-1437	155	36	into	into	ADP
admet-1437	155	37	log	log	NOUN
admet-1437	155	38	-	-	PUNCT
admet-1437	155	39	normal	normal	ADJ
admet-1437	155	40	distributions	distribution	NOUN
admet-1437	155	41	are	be	AUX
admet-1437	155	42	outlined	outline	VERB
admet-1437	155	43	in	in	ADP
admet-1437	155	44	table	table	NOUN
admet-1437	155	45	2	2	NUM
admet-1437	155	46	.	.	PUNCT
admet-1437	156	1	the	the	DET
admet-1437	156	2	volume	volume	NOUN
admet-1437	156	3	-	-	PUNCT
admet-1437	156	4	based	base	VERB
admet-1437	156	5	(	(	PUNCT
admet-1437	156	6	q3	q3	NOUN
admet-1437	156	7	)	)	PUNCT
admet-1437	156	8	percentiles	percentile	NOUN
admet-1437	156	9	x10,3	x10,3	PROPN
admet-1437	156	10	,	,	PUNCT
admet-1437	156	11	x50,3	x50,3	PROPN
admet-1437	157	1	(	(	PUNCT
admet-1437	157	2	median	median	PROPN
admet-1437	157	3	)	)	PUNCT
admet-1437	157	4	and	and	CCONJ
admet-1437	157	5	x90,3	x90,3	PROPN
admet-1437	157	6	of	of	ADP
admet-1437	157	7	the	the	DET
admet-1437	157	8	particle	particle	NOUN
admet-1437	157	9	size	size	NOUN
admet-1437	157	10	distributions	distribution	NOUN
admet-1437	157	11	are	be	AUX
admet-1437	157	12	reported	report	VERB
admet-1437	157	13	,	,	PUNCT
admet-1437	157	14	including	include	VERB
admet-1437	157	15	the	the	DET
admet-1437	157	16	individual	individual	ADJ
admet-1437	157	17	relative	relative	ADJ
admet-1437	157	18	difference	difference	NOUN
admet-1437	157	19	compared	compare	VERB
admet-1437	157	20	to	to	ADP
admet-1437	157	21	the	the	DET
admet-1437	157	22	experimental	experimental	ADJ
admet-1437	157	23	results	result	NOUN
admet-1437	157	24	as	as	SCONJ
admet-1437	157	25	obtained	obtain	VERB
admet-1437	157	26	from	from	ADP
admet-1437	157	27	lld	lld	PROPN
admet-1437	157	28	and	and	CCONJ
admet-1437	157	29	pcs	pc	NOUN
admet-1437	157	30	analysis	analysis	NOUN
admet-1437	157	31	.	.	PUNCT
admet-1437	158	1	further	far	ADV
admet-1437	158	2	,	,	PUNCT
admet-1437	158	3	the	the	DET
admet-1437	158	4	standard	standard	ADJ
admet-1437	158	5	deviation	deviation	NOUN
admet-1437	158	6	(	(	PUNCT
admet-1437	158	7	σ	σ	NOUN
admet-1437	158	8	)	)	PUNCT
admet-1437	158	9	of	of	ADP
admet-1437	158	10	the	the	DET
admet-1437	158	11	approximated	approximate	VERB
admet-1437	158	12	log	log	NOUN
admet-1437	158	13	-	-	PUNCT
admet-1437	158	14	normal	normal	ADJ
admet-1437	158	15	distribution	distribution	NOUN
admet-1437	158	16	is	be	AUX
admet-1437	158	17	reported	report	VERB
admet-1437	158	18	.	.	PUNCT
admet-1437	159	1	the	the	DET
admet-1437	159	2	uncertainty	uncertainty	NOUN
admet-1437	159	3	for	for	ADP
admet-1437	159	4	the	the	DET
admet-1437	159	5	ranges	range	NOUN
admet-1437	159	6	below	below	ADP
admet-1437	159	7	x10,3	x10,3	PROPN
admet-1437	159	8	and	and	CCONJ
admet-1437	159	9	above	above	ADV
admet-1437	159	10	x90,3	x90,3	PROPN
admet-1437	159	11	must	must	AUX
admet-1437	159	12	be	be	AUX
admet-1437	159	13	highlighted	highlight	VERB
admet-1437	159	14	as	as	SCONJ
admet-1437	159	15	here	here	ADV
admet-1437	159	16	experimental	experimental	ADJ
admet-1437	159	17	results	result	NOUN
admet-1437	159	18	were	be	AUX
admet-1437	159	19	extrapolated	extrapolate	VERB
admet-1437	159	20	.	.	PUNCT
admet-1437	160	1	however	however	ADV
admet-1437	160	2	,	,	PUNCT
admet-1437	160	3	the	the	DET
admet-1437	160	4	obtained	obtain	VERB
admet-1437	160	5	difference	difference	NOUN
admet-1437	160	6	by	by	ADP
admet-1437	160	7	the	the	DET
admet-1437	160	8	approximation	approximation	NOUN
admet-1437	160	9	of	of	ADP
admet-1437	160	10	the	the	DET
admet-1437	160	11	lognormal	lognormal	ADJ
admet-1437	160	12	distribution	distribution	NOUN
admet-1437	160	13	fit	fit	NOUN
admet-1437	160	14	is	be	AUX
admet-1437	160	15	considered	consider	VERB
admet-1437	160	16	appropriate	appropriate	ADJ
admet-1437	160	17	.	.	PUNCT
admet-1437	161	1	it	it	PRON
admet-1437	161	2	should	should	AUX
admet-1437	161	3	be	be	AUX
admet-1437	161	4	noted	note	VERB
admet-1437	161	5	that	that	SCONJ
admet-1437	161	6	analytical	analytical	ADJ
admet-1437	161	7	centrifugation	centrifugation	NOUN
admet-1437	161	8	is	be	AUX
admet-1437	161	9	presumed	presume	VERB
admet-1437	161	10	to	to	PART
admet-1437	161	11	be	be	AUX
admet-1437	161	12	a	a	DET
admet-1437	161	13	more	more	ADV
admet-1437	161	14	accurate	accurate	ADJ
admet-1437	161	15	technique	technique	NOUN
admet-1437	161	16	to	to	PART
admet-1437	161	17	characterize	characterize	VERB
admet-1437	161	18	the	the	DET
admet-1437	161	19	entire	entire	ADJ
admet-1437	161	20	nanocrystal	nanocrystal	ADJ
admet-1437	161	21	particle	particle	NOUN
admet-1437	161	22	size	size	NOUN
admet-1437	161	23	distribution	distribution	NOUN
admet-1437	161	24	.	.	PUNCT
admet-1437	162	1	the	the	DET
admet-1437	162	2	obtained	obtain	VERB
admet-1437	162	3	admet	admet	PROPN
admet-1437	162	4	&	&	CCONJ
admet-1437	162	5	dmpk	dmpk	PROPN
admet-1437	162	6	10(4	10(4	NUM
admet-1437	162	7	)	)	PUNCT
admet-1437	162	8	(	(	PUNCT
admet-1437	162	9	2022	2022	NUM
admet-1437	162	10	)	)	PUNCT
admet-1437	162	11	253	253	NUM
admet-1437	162	12	-	-	SYM
admet-1437	162	13	287	287	NUM
admet-1437	162	14	modeling	modeling	NOUN
admet-1437	162	15	of	of	ADP
admet-1437	162	16	drug	drug	NOUN
admet-1437	162	17	nanocrystals	nanocrystal	NOUN
admet-1437	162	18	dissolution	dissolution	NOUN
admet-1437	162	19	doi	doi	PROPN
admet-1437	162	20	:	:	PUNCT
admet-1437	162	21	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	162	22	261	261	NUM
admet-1437	162	23	results	result	NOUN
admet-1437	162	24	of	of	ADP
admet-1437	162	25	the	the	DET
admet-1437	162	26	nanocrystal	nanocrystal	ADJ
admet-1437	162	27	suspensions	suspension	NOUN
admet-1437	162	28	show	show	VERB
admet-1437	162	29	the	the	DET
admet-1437	162	30	wide	wide	ADJ
admet-1437	162	31	range	range	NOUN
admet-1437	162	32	of	of	ADP
admet-1437	162	33	particle	particle	NOUN
admet-1437	162	34	size	size	NOUN
admet-1437	162	35	distributions	distribution	NOUN
admet-1437	162	36	manufactured	manufacture	VERB
admet-1437	162	37	,	,	PUNCT
admet-1437	162	38	well	well	ADV
admet-1437	162	39	within	within	ADP
admet-1437	162	40	the	the	DET
admet-1437	162	41	range	range	NOUN
admet-1437	162	42	of	of	ADP
admet-1437	162	43	conventional	conventional	ADJ
admet-1437	162	44	products	product	NOUN
admet-1437	162	45	above	above	ADP
admet-1437	162	46	150	150	NUM
admet-1437	162	47	nm	nm	NOUN
admet-1437	162	48	and	and	CCONJ
admet-1437	162	49	within	within	ADP
admet-1437	162	50	the	the	DET
admet-1437	162	51	sub-100	sub-100	NOUN
admet-1437	162	52	nm	nm	ADJ
admet-1437	162	53	range	range	NOUN
admet-1437	162	54	.	.	PUNCT
admet-1437	163	1	the	the	DET
admet-1437	163	2	finest	fine	ADJ
admet-1437	163	3	nanocrystal	nanocrystal	ADJ
admet-1437	163	4	particle	particle	NOUN
admet-1437	163	5	size	size	NOUN
admet-1437	163	6	distribution	distribution	NOUN
admet-1437	163	7	was	be	AUX
admet-1437	163	8	obtained	obtain	VERB
admet-1437	163	9	for	for	ADP
admet-1437	163	10	experiment	experiment	NOUN
admet-1437	163	11	no	no	NOUN
admet-1437	163	12	.	.	NOUN
admet-1437	163	13	8	8	NUM
admet-1437	163	14	,	,	PUNCT
admet-1437	163	15	with	with	ADP
admet-1437	163	16	most	most	ADJ
admet-1437	163	17	particles	particle	NOUN
admet-1437	163	18	below	below	ADP
admet-1437	163	19	100	100	NUM
admet-1437	163	20	nm	nm	NOUN
admet-1437	163	21	.	.	PUNCT
admet-1437	164	1	interestingly	interestingly	ADV
admet-1437	164	2	,	,	PUNCT
admet-1437	164	3	the	the	DET
admet-1437	164	4	standard	standard	ADJ
admet-1437	164	5	deviation	deviation	NOUN
admet-1437	164	6	for	for	ADP
admet-1437	164	7	the	the	DET
admet-1437	164	8	wet	wet	ADJ
admet-1437	164	9	media	medium	NOUN
admet-1437	164	10	milled	mill	VERB
admet-1437	164	11	suspensions	suspension	NOUN
admet-1437	164	12	,	,	PUNCT
admet-1437	164	13	including	include	VERB
admet-1437	164	14	experiments	experiment	NOUN
admet-1437	164	15	no	no	INTJ
admet-1437	164	16	.	.	NOUN
admet-1437	164	17	2	2	NUM
admet-1437	164	18	to	to	PART
admet-1437	164	19	8	8	NUM
admet-1437	164	20	is	be	AUX
admet-1437	164	21	quite	quite	ADV
admet-1437	164	22	comparable	comparable	ADJ
admet-1437	164	23	.	.	PUNCT
admet-1437	165	1	table	table	NOUN
admet-1437	165	2	2	2	NUM
admet-1437	165	3	.	.	PUNCT
admet-1437	165	4	volume	volume	NOUN
admet-1437	165	5	-	-	PUNCT
admet-1437	165	6	based	base	VERB
admet-1437	165	7	(	(	PUNCT
admet-1437	165	8	q3	q3	NOUN
admet-1437	165	9	)	)	PUNCT
admet-1437	165	10	particle	particle	NOUN
admet-1437	165	11	size	size	NOUN
admet-1437	165	12	distribution	distribution	NOUN
admet-1437	165	13	percentiles	percentile	NOUN
admet-1437	165	14	(	(	PUNCT
admet-1437	165	15	x10,3	x10,3	PROPN
admet-1437	165	16	,	,	PUNCT
admet-1437	165	17	x50,3	x50,3	PROPN
admet-1437	165	18	and	and	CCONJ
admet-1437	165	19	x90,3	x90,3	NUM
admet-1437	165	20	)	)	PUNCT
admet-1437	165	21	and	and	CCONJ
admet-1437	165	22	standard	standard	ADJ
admet-1437	165	23	deviation	deviation	NOUN
admet-1437	165	24	(	(	PUNCT
admet-1437	165	25	σ	σ	NOUN
admet-1437	165	26	)	)	PUNCT
admet-1437	165	27	for	for	ADP
admet-1437	165	28	approximated	approximate	VERB
admet-1437	165	29	dimensionless	dimensionless	NOUN
admet-1437	165	30	log	log	NOUN
admet-1437	165	31	-	-	PUNCT
admet-1437	165	32	normal	normal	ADJ
admet-1437	165	33	distributions	distribution	NOUN
admet-1437	165	34	used	use	VERB
admet-1437	165	35	as	as	ADP
admet-1437	165	36	input	input	NOUN
admet-1437	165	37	for	for	ADP
admet-1437	165	38	the	the	DET
admet-1437	165	39	numerical	numerical	ADJ
admet-1437	165	40	model	model	NOUN
admet-1437	165	41	and	and	CCONJ
admet-1437	165	42	deviation	deviation	NOUN
admet-1437	165	43	(	(	PUNCT
admet-1437	165	44	in	in	ADP
admet-1437	165	45	brackets	bracket	NOUN
admet-1437	165	46	)	)	PUNCT
admet-1437	165	47	to	to	ADP
admet-1437	165	48	experimental	experimental	ADJ
admet-1437	165	49	particle	particle	NOUN
admet-1437	165	50	size	size	NOUN
admet-1437	165	51	distributions	distribution	NOUN
admet-1437	165	52	determined	determine	VERB
admet-1437	165	53	by	by	ADP
admet-1437	165	54	laser	laser	NOUN
admet-1437	165	55	light	light	ADJ
admet-1437	165	56	diffraction	diffraction	NOUN
admet-1437	165	57	(	(	PUNCT
admet-1437	165	58	lld	lld	PROPN
admet-1437	165	59	)	)	PUNCT
admet-1437	165	60	for	for	ADP
admet-1437	165	61	experiment	experiment	NOUN
admet-1437	165	62	no	no	NOUN
admet-1437	165	63	.	.	NOUN
admet-1437	165	64	1	1	NUM
admet-1437	165	65	and	and	CCONJ
admet-1437	165	66	by	by	ADP
admet-1437	165	67	photon	photon	NOUN
admet-1437	165	68	correlation	correlation	NOUN
admet-1437	165	69	spectroscopy	spectroscopy	NOUN
admet-1437	165	70	(	(	PUNCT
admet-1437	165	71	pcs	pc	NOUN
admet-1437	165	72	)	)	PUNCT
admet-1437	165	73	for	for	ADP
admet-1437	165	74	experiments	experiment	NOUN
admet-1437	165	75	no	no	INTJ
admet-1437	165	76	.	.	NOUN
admet-1437	165	77	2	2	NUM
admet-1437	165	78	to	to	PART
admet-1437	165	79	8	8	NUM
admet-1437	165	80	.	.	PUNCT
admet-1437	166	1	experiment	experiment	NOUN
admet-1437	166	2	no	no	PROPN
admet-1437	166	3	.	.	PUNCT
admet-1437	166	4	particle	particle	NOUN
admet-1437	166	5	size	size	NOUN
admet-1437	166	6	x10,3	x10,3	PROPN
admet-1437	166	7	/	/	SYM
admet-1437	166	8	nm	nm	ADJ
admet-1437	166	9	particle	particle	NOUN
admet-1437	166	10	size	size	NOUN
admet-1437	166	11	x50,3	x50,3	PROPN
admet-1437	166	12	/	/	SYM
admet-1437	166	13	nm	nm	NOUN
admet-1437	166	14	particle	particle	NOUN
admet-1437	166	15	size	size	NOUN
admet-1437	166	16	x90,3	x90,3	PROPN
admet-1437	166	17	/	/	SYM
admet-1437	166	18	nm	nm	ADV
admet-1437	166	19	standard	standard	ADJ
admet-1437	166	20	deviation	deviation	NOUN
admet-1437	166	21	σ	σ	X
admet-1437	166	22	/	/	SYM
admet-1437	166	23	1	1	NUM
admet-1437	166	24	1116	1116	NUM
admet-1437	166	25	(	(	PUNCT
admet-1437	166	26	-0.4	-0.4	NUM
admet-1437	166	27	%	%	NOUN
admet-1437	166	28	)	)	PUNCT
admet-1437	166	29	2443	2443	NUM
admet-1437	166	30	(	(	PUNCT
admet-1437	166	31	-1.9	-1.9	NUM
admet-1437	166	32	%	%	NOUN
admet-1437	166	33	)	)	PUNCT
admet-1437	166	34	5344	5344	NUM
admet-1437	166	35	(	(	PUNCT
admet-1437	166	36	+0.1	+0.1	NOUN
admet-1437	166	37	%	%	NOUN
admet-1437	166	38	)	)	PUNCT
admet-1437	166	39	0.611	0.611	NUM
admet-1437	166	40	2	2	NUM
admet-1437	166	41	152	152	NUM
admet-1437	166	42	(	(	PUNCT
admet-1437	166	43	-3.4	-3.4	NOUN
admet-1437	166	44	%	%	NOUN
admet-1437	166	45	)	)	PUNCT
admet-1437	166	46	261	261	NUM
admet-1437	166	47	(	(	PUNCT
admet-1437	166	48	+1.0	+1.0	NUM
admet-1437	166	49	%	%	NOUN
admet-1437	166	50	)	)	PUNCT
admet-1437	166	51	449	449	NUM
admet-1437	166	52	(	(	PUNCT
admet-1437	166	53	-3.6	-3.6	NUM
admet-1437	166	54	%	%	NOUN
admet-1437	166	55	)	)	PUNCT
admet-1437	166	56	0.422	0.422	NUM
admet-1437	166	57	3	3	NUM
admet-1437	166	58	116	116	NUM
admet-1437	166	59	(	(	PUNCT
admet-1437	166	60	-2.2	-2.2	NUM
admet-1437	166	61	%	%	NOUN
admet-1437	166	62	)	)	PUNCT
admet-1437	166	63	201	201	NUM
admet-1437	166	64	(	(	PUNCT
admet-1437	166	65	+0.0	+0.0	NUM
admet-1437	166	66	%	%	NOUN
admet-1437	166	67	)	)	PUNCT
admet-1437	166	68	348	348	NUM
admet-1437	166	69	(	(	PUNCT
admet-1437	166	70	-0.9	-0.9	NUM
admet-1437	166	71	%	%	NOUN
admet-1437	166	72	)	)	PUNCT
admet-1437	166	73	0.427	0.427	NUM
admet-1437	166	74	4	4	NUM
admet-1437	166	75	78	78	NUM
admet-1437	166	76	(	(	PUNCT
admet-1437	166	77	-6.0	-6.0	PROPN
admet-1437	166	78	%	%	NOUN
admet-1437	166	79	)	)	PUNCT
admet-1437	166	80	140	140	NUM
admet-1437	166	81	(	(	PUNCT
admet-1437	166	82	+1.4	+1.4	NUM
admet-1437	166	83	%	%	NOUN
admet-1437	166	84	)	)	PUNCT
admet-1437	166	85	252	252	NUM
admet-1437	166	86	(	(	PUNCT
admet-1437	166	87	-3.2	-3.2	PROPN
admet-1437	166	88	%	%	NOUN
admet-1437	166	89	)	)	PUNCT
admet-1437	166	90	0.456	0.456	NUM
admet-1437	166	91	5	5	NUM
admet-1437	166	92	57	57	NUM
admet-1437	166	93	(	(	PUNCT
admet-1437	166	94	-5.9	-5.9	NOUN
admet-1437	166	95	%	%	NOUN
admet-1437	166	96	)	)	PUNCT
admet-1437	166	97	111	111	NUM
admet-1437	166	98	(	(	PUNCT
admet-1437	166	99	+2.2	+2.2	NUM
admet-1437	166	100	%	%	NOUN
admet-1437	166	101	)	)	PUNCT
admet-1437	166	102	213	213	NUM
admet-1437	166	103	(	(	PUNCT
admet-1437	166	104	-3.5	-3.5	NUM
admet-1437	166	105	%	%	NOUN
admet-1437	166	106	)	)	PUNCT
admet-1437	166	107	0.513	0.513	NUM
admet-1437	166	108	6	6	NUM
admet-1437	166	109	53	53	NUM
admet-1437	166	110	(	(	PUNCT
admet-1437	166	111	-7.2	-7.2	NOUN
admet-1437	166	112	%	%	NOUN
admet-1437	166	113	)	)	PUNCT
admet-1437	166	114	93	93	NUM
admet-1437	166	115	(	(	PUNCT
admet-1437	166	116	+2.5	+2.5	ADJ
admet-1437	166	117	%	%	NOUN
admet-1437	166	118	)	)	PUNCT
admet-1437	166	119	162	162	NUM
admet-1437	166	120	(	(	PUNCT
admet-1437	166	121	-7.1	-7.1	INTJ
admet-1437	166	122	%	%	NOUN
admet-1437	166	123	)	)	PUNCT
admet-1437	166	124	0.432	0.432	NUM
admet-1437	166	125	7	7	NUM
admet-1437	166	126	53	53	NUM
admet-1437	166	127	(	(	PUNCT
admet-1437	166	128	-6.4	-6.4	ADJ
admet-1437	166	129	%	%	NOUN
admet-1437	166	130	)	)	PUNCT
admet-1437	166	131	90	90	NUM
admet-1437	166	132	(	(	PUNCT
admet-1437	166	133	+2.8	+2.8	PROPN
admet-1437	166	134	%	%	NOUN
admet-1437	166	135	)	)	PUNCT
admet-1437	166	136	150	150	NUM
admet-1437	166	137	(	(	PUNCT
admet-1437	166	138	-7.0	-7.0	PROPN
admet-1437	166	139	%	%	NOUN
admet-1437	166	140	)	)	PUNCT
admet-1437	166	141	0.404	0.404	NUM
admet-1437	166	142	8	8	NUM
admet-1437	166	143	47	47	NUM
admet-1437	166	144	(	(	PUNCT
admet-1437	166	145	-4.3	-4.3	PROPN
admet-1437	166	146	%	%	NOUN
admet-1437	166	147	)	)	PUNCT
admet-1437	166	148	79	79	NUM
admet-1437	166	149	(	(	PUNCT
admet-1437	166	150	+1.1	+1.1	NUM
admet-1437	166	151	%	%	NOUN
admet-1437	166	152	)	)	PUNCT
admet-1437	166	153	133	133	NUM
admet-1437	166	154	(	(	PUNCT
admet-1437	166	155	-3.9	-3.9	NOUN
admet-1437	166	156	%	%	NOUN
admet-1437	166	157	)	)	PUNCT
admet-1437	166	158	0.402	0.402	NUM
admet-1437	166	159	the	the	DET
admet-1437	166	160	corresponding	corresponding	ADJ
admet-1437	166	161	scanning	scanning	NOUN
admet-1437	166	162	electron	electron	NOUN
admet-1437	166	163	micrographs	micrograph	NOUN
admet-1437	166	164	of	of	ADP
admet-1437	166	165	the	the	DET
admet-1437	166	166	manufactured	manufacture	VERB
admet-1437	166	167	nanocrystals	nanocrystal	NOUN
admet-1437	166	168	are	be	AUX
admet-1437	166	169	shown	show	VERB
admet-1437	166	170	in	in	ADP
admet-1437	166	171	figure	figure	NOUN
admet-1437	166	172	2	2	NUM
admet-1437	166	173	.	.	PUNCT
admet-1437	167	1	the	the	DET
admet-1437	167	2	different	different	ADJ
admet-1437	167	3	levels	level	NOUN
admet-1437	167	4	of	of	ADP
admet-1437	167	5	magnification	magnification	NOUN
admet-1437	167	6	of	of	ADP
admet-1437	167	7	the	the	DET
admet-1437	167	8	micrographs	micrograph	NOUN
admet-1437	167	9	should	should	AUX
admet-1437	167	10	be	be	AUX
admet-1437	167	11	noted	note	VERB
admet-1437	167	12	.	.	PUNCT
admet-1437	168	1	the	the	DET
admet-1437	168	2	coarse	coarse	ADJ
admet-1437	168	3	crystals	crystal	NOUN
admet-1437	168	4	are	be	AUX
admet-1437	168	5	shown	show	VERB
admet-1437	168	6	in	in	ADP
admet-1437	168	7	figure	figure	NOUN
admet-1437	168	8	2(a	2(a	NUM
admet-1437	168	9	)	)	PUNCT
admet-1437	168	10	and	and	CCONJ
admet-1437	168	11	correspond	correspond	VERB
admet-1437	168	12	to	to	PART
admet-1437	168	13	experiment	experiment	VERB
admet-1437	168	14	no	no	INTJ
admet-1437	168	15	.	.	NOUN
admet-1437	169	1	1	1	NUM
admet-1437	169	2	.	.	X
admet-1437	169	3	coarse	coarse	ADJ
admet-1437	169	4	crystals	crystal	NOUN
admet-1437	169	5	with	with	ADP
admet-1437	169	6	a	a	DET
admet-1437	169	7	particle	particle	NOUN
admet-1437	169	8	size	size	NOUN
admet-1437	169	9	of	of	ADP
admet-1437	169	10	about	about	ADV
admet-1437	169	11	5	5	NUM
admet-1437	169	12	μm	μm	NUM
admet-1437	169	13	and	and	CCONJ
admet-1437	169	14	fine	fine	ADJ
admet-1437	169	15	crystals	crystal	NOUN
admet-1437	169	16	below	below	ADP
admet-1437	169	17	1	1	NUM
admet-1437	169	18	μm	μm	NOUN
admet-1437	169	19	can	can	AUX
admet-1437	169	20	be	be	AUX
admet-1437	169	21	seen	see	VERB
admet-1437	169	22	in	in	ADP
admet-1437	169	23	the	the	DET
admet-1437	169	24	micrograph	micrograph	NOUN
admet-1437	169	25	and	and	CCONJ
admet-1437	169	26	match	match	VERB
admet-1437	169	27	well	well	ADV
admet-1437	169	28	to	to	ADP
admet-1437	169	29	the	the	DET
admet-1437	169	30	quantitative	quantitative	ADJ
admet-1437	169	31	particle	particle	NOUN
admet-1437	169	32	size	size	NOUN
admet-1437	169	33	distribution	distribution	NOUN
admet-1437	169	34	according	accord	VERB
admet-1437	169	35	to	to	ADP
admet-1437	169	36	table	table	NOUN
admet-1437	169	37	2	2	NUM
admet-1437	169	38	.	.	PUNCT
admet-1437	169	39	nanocrystals	nanocrystal	NOUN
admet-1437	169	40	manufactured	manufacture	VERB
admet-1437	169	41	by	by	ADP
admet-1437	169	42	wet	wet	ADJ
admet-1437	169	43	media	medium	NOUN
admet-1437	169	44	milling	milling	NOUN
admet-1437	169	45	are	be	AUX
admet-1437	169	46	shown	show	VERB
admet-1437	169	47	in	in	ADP
admet-1437	169	48	figure	figure	NOUN
admet-1437	169	49	2(b	2(b	NUM
admet-1437	169	50	)	)	PUNCT
admet-1437	169	51	to	to	ADP
admet-1437	169	52	(	(	PUNCT
admet-1437	169	53	h	h	NOUN
admet-1437	169	54	)	)	PUNCT
admet-1437	169	55	.	.	PUNCT
admet-1437	170	1	even	even	ADV
admet-1437	170	2	at	at	ADP
admet-1437	170	3	the	the	DET
admet-1437	170	4	highest	high	ADJ
admet-1437	170	5	magnification	magnification	NOUN
admet-1437	170	6	,	,	PUNCT
admet-1437	170	7	nanocrystals	nanocrystal	NOUN
admet-1437	170	8	demonstrate	demonstrate	VERB
admet-1437	170	9	throughout	throughout	ADP
admet-1437	170	10	all	all	DET
admet-1437	170	11	experiments	experiment	NOUN
admet-1437	170	12	quite	quite	ADV
admet-1437	170	13	smooth	smooth	ADJ
admet-1437	170	14	surfaces	surface	NOUN
admet-1437	170	15	.	.	PUNCT
admet-1437	171	1	this	this	DET
admet-1437	171	2	observation	observation	NOUN
admet-1437	171	3	corresponds	correspond	VERB
admet-1437	171	4	to	to	ADP
admet-1437	171	5	other	other	ADJ
admet-1437	171	6	investigations	investigation	NOUN
admet-1437	171	7	where	where	SCONJ
admet-1437	171	8	the	the	DET
admet-1437	171	9	surface	surface	NOUN
admet-1437	171	10	of	of	ADP
admet-1437	171	11	wet	wet	ADJ
admet-1437	171	12	media	medium	NOUN
admet-1437	171	13	milled	mill	VERB
admet-1437	171	14	organic	organic	ADJ
admet-1437	171	15	crystals	crystal	NOUN
admet-1437	171	16	is	be	AUX
admet-1437	171	17	also	also	ADV
admet-1437	171	18	determined	determine	VERB
admet-1437	171	19	by	by	ADP
admet-1437	171	20	the	the	DET
admet-1437	171	21	solid	solid	ADJ
admet-1437	171	22	-	-	PUNCT
admet-1437	171	23	liquid	liquid	ADJ
admet-1437	171	24	equilibrium	equilibrium	NOUN
admet-1437	171	25	and	and	CCONJ
admet-1437	171	26	not	not	PART
admet-1437	171	27	merely	merely	ADV
admet-1437	171	28	by	by	ADP
admet-1437	171	29	ordinary	ordinary	ADJ
admet-1437	171	30	mechanical	mechanical	ADJ
admet-1437	171	31	fracture	fracture	NOUN
admet-1437	172	1	[	[	X
admet-1437	172	2	81	81	NUM
admet-1437	172	3	]	]	PUNCT
admet-1437	172	4	.	.	PUNCT
admet-1437	173	1	figure	figure	NOUN
admet-1437	173	2	2(b	2(b	NUM
admet-1437	173	3	)	)	PUNCT
admet-1437	173	4	shows	show	VERB
admet-1437	173	5	the	the	DET
admet-1437	173	6	coarsest	coarse	ADJ
admet-1437	173	7	nanocrystals	nanocrystal	NOUN
admet-1437	173	8	manufactured	manufacture	VERB
admet-1437	173	9	by	by	ADP
admet-1437	173	10	wet	wet	ADJ
admet-1437	173	11	media	medium	NOUN
admet-1437	173	12	milling	mill	VERB
admet-1437	173	13	with	with	ADP
admet-1437	173	14	one	one	NUM
admet-1437	173	15	larger	large	ADJ
admet-1437	173	16	sized	sized	ADJ
admet-1437	173	17	population	population	NOUN
admet-1437	173	18	of	of	ADP
admet-1437	173	19	irregular	irregular	ADJ
admet-1437	173	20	,	,	PUNCT
admet-1437	173	21	square	square	ADJ
admet-1437	173	22	-	-	PUNCT
admet-1437	173	23	shaped	shape	VERB
admet-1437	173	24	particles	particle	NOUN
admet-1437	173	25	with	with	ADP
admet-1437	173	26	smooth	smooth	ADJ
admet-1437	173	27	planes	plane	NOUN
admet-1437	173	28	and	and	CCONJ
admet-1437	173	29	a	a	DET
admet-1437	173	30	second	second	ADJ
admet-1437	173	31	smaller	small	ADJ
admet-1437	173	32	-	-	PUNCT
admet-1437	173	33	sized	sized	ADJ
admet-1437	173	34	population	population	NOUN
admet-1437	173	35	of	of	ADP
admet-1437	173	36	irregular	irregular	ADJ
admet-1437	173	37	,	,	PUNCT
admet-1437	173	38	round	round	ADV
admet-1437	173	39	-	-	PUNCT
admet-1437	173	40	shaped	shape	VERB
admet-1437	173	41	particles	particle	NOUN
admet-1437	173	42	.	.	PUNCT
admet-1437	174	1	interestingly	interestingly	ADV
admet-1437	174	2	,	,	PUNCT
admet-1437	174	3	the	the	DET
admet-1437	174	4	population	population	NOUN
admet-1437	174	5	of	of	ADP
admet-1437	174	6	irregular	irregular	ADJ
admet-1437	174	7	,	,	PUNCT
admet-1437	174	8	square	square	ADJ
admet-1437	174	9	-	-	PUNCT
admet-1437	174	10	shaped	shape	VERB
admet-1437	174	11	particles	particle	NOUN
admet-1437	174	12	is	be	AUX
admet-1437	174	13	decreasing	decrease	VERB
admet-1437	174	14	with	with	ADP
admet-1437	174	15	further	further	ADJ
admet-1437	174	16	size	size	NOUN
admet-1437	174	17	reduction	reduction	NOUN
admet-1437	174	18	of	of	ADP
admet-1437	174	19	the	the	DET
admet-1437	174	20	nanocrystals	nanocrystal	NOUN
admet-1437	174	21	,	,	PUNCT
admet-1437	174	22	as	as	SCONJ
admet-1437	174	23	can	can	AUX
admet-1437	174	24	be	be	AUX
admet-1437	174	25	seen	see	VERB
admet-1437	174	26	upon	upon	SCONJ
admet-1437	174	27	the	the	DET
admet-1437	174	28	evolution	evolution	NOUN
admet-1437	174	29	from	from	ADP
admet-1437	174	30	figure	figure	NOUN
admet-1437	174	31	2(c	2(c	NUM
admet-1437	174	32	)	)	PUNCT
admet-1437	174	33	to	to	ADP
admet-1437	174	34	(	(	PUNCT
admet-1437	174	35	h	h	NOUN
admet-1437	174	36	)	)	PUNCT
admet-1437	174	37	.	.	PUNCT
admet-1437	175	1	the	the	DET
admet-1437	175	2	population	population	NOUN
admet-1437	175	3	of	of	ADP
admet-1437	175	4	irregular	irregular	ADJ
admet-1437	175	5	,	,	PUNCT
admet-1437	175	6	square	square	ADJ
admet-1437	175	7	-	-	PUNCT
admet-1437	175	8	shaped	shape	VERB
admet-1437	175	9	particles	particle	NOUN
admet-1437	175	10	with	with	ADP
admet-1437	175	11	smooth	smooth	ADJ
admet-1437	175	12	planes	plane	NOUN
admet-1437	175	13	no	no	ADV
admet-1437	175	14	longer	long	ADV
admet-1437	175	15	exists	exist	VERB
admet-1437	175	16	for	for	ADP
admet-1437	175	17	the	the	DET
admet-1437	175	18	smallest	small	ADJ
admet-1437	175	19	nanocrystals	nanocrystal	NOUN
admet-1437	175	20	obtained	obtain	VERB
admet-1437	175	21	,	,	PUNCT
admet-1437	175	22	see	see	VERB
admet-1437	175	23	figure	figure	NOUN
admet-1437	175	24	2(h	2(h	NUM
admet-1437	175	25	)	)	PUNCT
admet-1437	175	26	.	.	PUNCT
admet-1437	176	1	most	most	ADJ
admet-1437	176	2	of	of	ADP
admet-1437	176	3	the	the	DET
admet-1437	176	4	particles	particle	NOUN
admet-1437	176	5	of	of	ADP
admet-1437	176	6	the	the	DET
admet-1437	176	7	finest	fine	ADJ
admet-1437	176	8	manufactured	manufacture	VERB
admet-1437	176	9	nanocrystals	nanocrystal	NOUN
admet-1437	176	10	in	in	ADP
admet-1437	176	11	figure	figure	NOUN
admet-1437	176	12	2(h	2(h	NUM
admet-1437	176	13	)	)	PUNCT
admet-1437	176	14	are	be	AUX
admet-1437	176	15	well	well	ADV
admet-1437	176	16	below	below	ADP
admet-1437	176	17	100	100	NUM
admet-1437	176	18	nm	nm	NOUN
admet-1437	176	19	and	and	CCONJ
admet-1437	176	20	correspond	correspond	VERB
admet-1437	176	21	well	well	ADV
admet-1437	176	22	with	with	ADP
admet-1437	176	23	the	the	DET
admet-1437	176	24	quantitative	quantitative	ADJ
admet-1437	176	25	results	result	NOUN
admet-1437	176	26	in	in	ADP
admet-1437	176	27	table	table	NOUN
admet-1437	176	28	2	2	NUM
admet-1437	176	29	.	.	PUNCT
admet-1437	177	1	the	the	DET
admet-1437	177	2	entire	entire	ADJ
admet-1437	177	3	nanocrystal	nanocrystal	ADJ
admet-1437	177	4	population	population	NOUN
admet-1437	177	5	shows	show	VERB
admet-1437	177	6	irregular	irregular	ADJ
admet-1437	177	7	,	,	PUNCT
admet-1437	177	8	rounded	rounded	ADJ
admet-1437	177	9	-	-	PUNCT
admet-1437	177	10	shaped	shape	VERB
admet-1437	177	11	particles	particle	NOUN
admet-1437	177	12	and	and	CCONJ
admet-1437	177	13	even	even	ADV
admet-1437	177	14	ultrafine	ultrafine	ADJ
admet-1437	177	15	nanocrystals	nanocrystal	NOUN
admet-1437	177	16	with	with	ADP
admet-1437	177	17	almost	almost	ADV
admet-1437	177	18	sphere	sphere	NOUN
admet-1437	177	19	-	-	PUNCT
admet-1437	177	20	like	like	ADJ
admet-1437	177	21	shape	shape	NOUN
admet-1437	177	22	.	.	PUNCT
admet-1437	178	1	on	on	ADP
admet-1437	178	2	closer	close	ADJ
admet-1437	178	3	examination	examination	NOUN
admet-1437	178	4	,	,	PUNCT
admet-1437	178	5	ultrafine	ultrafine	NOUN
admet-1437	178	6	nanocrystals	nanocrystal	NOUN
admet-1437	178	7	with	with	ADP
admet-1437	178	8	a	a	DET
admet-1437	178	9	particle	particle	NOUN
admet-1437	178	10	size	size	NOUN
admet-1437	178	11	of	of	ADP
admet-1437	178	12	about	about	ADV
admet-1437	178	13	20	20	NUM
admet-1437	178	14	nm	nm	NOUN
admet-1437	178	15	can	can	AUX
admet-1437	178	16	be	be	AUX
admet-1437	178	17	found	find	VERB
admet-1437	178	18	.	.	PUNCT
admet-1437	179	1	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	X
admet-1437	179	2	bonhoeffer	bonhoeffer	PROPN
admet-1437	179	3	et	et	PROPN
admet-1437	179	4	al	al	PROPN
admet-1437	179	5	.	.	PROPN
admet-1437	179	6	admet	admet	PROPN
admet-1437	179	7	&	&	CCONJ
admet-1437	179	8	dmpk	dmpk	PROPN
admet-1437	179	9	10(4	10(4	NUM
admet-1437	179	10	)	)	PUNCT
admet-1437	179	11	(	(	PUNCT
admet-1437	179	12	2022	2022	NUM
admet-1437	179	13	)	)	PUNCT
admet-1437	179	14	253	253	NUM
admet-1437	179	15	-	-	SYM
admet-1437	179	16	287	287	NUM
admet-1437	179	17	262	262	NUM
admet-1437	179	18	figure	figure	NOUN
admet-1437	179	19	2	2	NUM
admet-1437	179	20	.	.	PUNCT
admet-1437	179	21	micrographs	micrograph	NOUN
admet-1437	179	22	of	of	ADP
admet-1437	179	23	nanocrystals	nanocrystal	NOUN
admet-1437	179	24	as	as	SCONJ
admet-1437	179	25	determined	determine	VERB
admet-1437	179	26	by	by	ADP
admet-1437	179	27	scanning	scan	VERB
admet-1437	179	28	electron	electron	NOUN
admet-1437	179	29	microscopy	microscopy	NOUN
admet-1437	179	30	(	(	PUNCT
admet-1437	179	31	sem	sem	NOUN
admet-1437	179	32	)	)	PUNCT
admet-1437	179	33	corresponding	correspond	VERB
admet-1437	179	34	to	to	ADP
admet-1437	179	35	table	table	NOUN
admet-1437	179	36	2	2	NUM
admet-1437	179	37	.	.	PUNCT
admet-1437	180	1	(	(	PUNCT
admet-1437	180	2	a	a	X
admet-1437	180	3	)	)	PUNCT
admet-1437	180	4	experiment	experiment	NOUN
admet-1437	180	5	no	no	NOUN
admet-1437	180	6	.	.	PROPN
admet-1437	180	7	1	1	NUM
admet-1437	180	8	,	,	PUNCT
admet-1437	180	9	x50,3	x50,3	PUNCT
admet-1437	181	1	=	=	SYM
admet-1437	181	2	2443	2443	NUM
admet-1437	181	3	nm	nm	NOUN
admet-1437	181	4	.	.	PUNCT
admet-1437	182	1	(	(	PUNCT
admet-1437	182	2	b	b	X
admet-1437	182	3	)	)	PUNCT
admet-1437	182	4	experiment	experiment	NOUN
admet-1437	182	5	no	no	NOUN
admet-1437	182	6	.	.	NOUN
admet-1437	182	7	2	2	NUM
admet-1437	182	8	,	,	PUNCT
admet-1437	182	9	x50,3	x50,3	PUNCT
admet-1437	183	1	=	=	PROPN
admet-1437	183	2	261	261	NUM
admet-1437	183	3	nm	nm	NOUN
admet-1437	183	4	.	.	PUNCT
admet-1437	184	1	(	(	PUNCT
admet-1437	184	2	c	c	X
admet-1437	184	3	)	)	PUNCT
admet-1437	184	4	experiment	experiment	NOUN
admet-1437	184	5	no	no	NOUN
admet-1437	184	6	.	.	NOUN
admet-1437	184	7	3	3	NUM
admet-1437	184	8	,	,	PUNCT
admet-1437	184	9	x50,3	x50,3	PUNCT
admet-1437	185	1	=	=	SYM
admet-1437	185	2	201	201	NUM
admet-1437	185	3	nm	nm	NOUN
admet-1437	185	4	.	.	PUNCT
admet-1437	186	1	(	(	PUNCT
admet-1437	186	2	d	d	X
admet-1437	186	3	)	)	PUNCT
admet-1437	186	4	experiment	experiment	NOUN
admet-1437	186	5	no	no	NOUN
admet-1437	186	6	.	.	NOUN
admet-1437	186	7	4	4	NUM
admet-1437	186	8	,	,	PUNCT
admet-1437	186	9	x50,3	x50,3	PUNCT
admet-1437	187	1	=	=	SYM
admet-1437	187	2	140	140	NUM
admet-1437	187	3	nm	nm	NOUN
admet-1437	187	4	.	.	PUNCT
admet-1437	188	1	(	(	PUNCT
admet-1437	188	2	e	e	NOUN
admet-1437	188	3	)	)	PUNCT
admet-1437	188	4	experiment	experiment	NOUN
admet-1437	188	5	no	no	NOUN
admet-1437	188	6	.	.	PROPN
admet-1437	188	7	5	5	NUM
admet-1437	188	8	,	,	PUNCT
admet-1437	188	9	x50,3	x50,3	PUNCT
admet-1437	189	1	=	=	SYM
admet-1437	189	2	111	111	NUM
admet-1437	189	3	nm	nm	NOUN
admet-1437	189	4	.	.	PUNCT
admet-1437	190	1	(	(	PUNCT
admet-1437	190	2	f	f	X
admet-1437	190	3	)	)	PUNCT
admet-1437	190	4	experiment	experiment	NOUN
admet-1437	190	5	no	no	NOUN
admet-1437	190	6	.	.	NOUN
admet-1437	190	7	6	6	NUM
admet-1437	190	8	,	,	PUNCT
admet-1437	190	9	x50,3	x50,3	PUNCT
admet-1437	191	1	=	=	SYM
admet-1437	191	2	93	93	NUM
admet-1437	191	3	nm	nm	NOUN
admet-1437	191	4	.	.	PUNCT
admet-1437	192	1	(	(	PUNCT
admet-1437	192	2	g	g	NOUN
admet-1437	192	3	)	)	PUNCT
admet-1437	192	4	experiment	experiment	NOUN
admet-1437	192	5	no	no	NOUN
admet-1437	192	6	.	.	PROPN
admet-1437	192	7	7	7	NUM
admet-1437	192	8	,	,	PUNCT
admet-1437	192	9	x50,3	x50,3	PUNCT
admet-1437	193	1	=	=	SYM
admet-1437	193	2	90	90	NUM
admet-1437	193	3	nm	nm	NOUN
admet-1437	193	4	.	.	PUNCT
admet-1437	194	1	(	(	PUNCT
admet-1437	194	2	h	h	NOUN
admet-1437	194	3	)	)	PUNCT
admet-1437	194	4	experiment	experiment	NOUN
admet-1437	194	5	no	no	NOUN
admet-1437	194	6	.	.	NOUN
admet-1437	194	7	8	8	NUM
admet-1437	194	8	,	,	PUNCT
admet-1437	194	9	x50,3	x50,3	PUNCT
admet-1437	195	1	=	=	SYM
admet-1437	195	2	79	79	NUM
admet-1437	195	3	nm	nm	NOUN
admet-1437	195	4	;	;	PUNCT
admet-1437	195	5	note	note	VERB
admet-1437	195	6	the	the	DET
admet-1437	195	7	different	different	ADJ
admet-1437	195	8	levels	level	NOUN
admet-1437	195	9	of	of	ADP
admet-1437	195	10	magnification	magnification	NOUN
admet-1437	195	11	of	of	ADP
admet-1437	195	12	the	the	DET
admet-1437	195	13	micrographs	micrograph	NOUN
admet-1437	195	14	.	.	PUNCT
admet-1437	196	1	admet	admet	PROPN
admet-1437	196	2	&	&	CCONJ
admet-1437	196	3	dmpk	dmpk	PROPN
admet-1437	196	4	10(4	10(4	NUM
admet-1437	196	5	)	)	PUNCT
admet-1437	196	6	(	(	PUNCT
admet-1437	196	7	2022	2022	NUM
admet-1437	196	8	)	)	PUNCT
admet-1437	196	9	253	253	NUM
admet-1437	196	10	-	-	SYM
admet-1437	196	11	287	287	NUM
admet-1437	196	12	modeling	modeling	NOUN
admet-1437	196	13	of	of	ADP
admet-1437	196	14	drug	drug	NOUN
admet-1437	196	15	nanocrystals	nanocrystal	NOUN
admet-1437	196	16	dissolution	dissolution	NOUN
admet-1437	196	17	doi	doi	PROPN
admet-1437	196	18	:	:	PUNCT
admet-1437	196	19	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	196	20	263	263	NUM
admet-1437	196	21	solid	solid	ADJ
admet-1437	196	22	-	-	PUNCT
admet-1437	196	23	state	state	NOUN
admet-1437	196	24	characterization	characterization	NOUN
admet-1437	196	25	of	of	ADP
admet-1437	196	26	nanocrystals	nanocrystal	NOUN
admet-1437	196	27	nanocrystals	nanocrystal	NOUN
admet-1437	196	28	can	can	AUX
admet-1437	196	29	be	be	AUX
admet-1437	196	30	seen	see	VERB
admet-1437	196	31	as	as	ADP
admet-1437	196	32	an	an	DET
admet-1437	196	33	intermediate	intermediate	ADJ
admet-1437	196	34	step	step	NOUN
admet-1437	196	35	in	in	ADP
admet-1437	196	36	the	the	DET
admet-1437	196	37	continuum	continuum	NOUN
admet-1437	196	38	between	between	ADP
admet-1437	196	39	perfectly	perfectly	ADV
admet-1437	196	40	crystalline	crystalline	ADJ
admet-1437	196	41	materials	material	NOUN
admet-1437	196	42	and	and	CCONJ
admet-1437	196	43	amorphous	amorphous	ADJ
admet-1437	196	44	phases	phase	NOUN
admet-1437	196	45	,	,	PUNCT
admet-1437	196	46	where	where	SCONJ
admet-1437	196	47	defects	defect	NOUN
admet-1437	196	48	and	and	CCONJ
admet-1437	196	49	surface	surface	NOUN
admet-1437	196	50	features	feature	NOUN
admet-1437	196	51	of	of	ADP
admet-1437	196	52	the	the	DET
admet-1437	196	53	crystalline	crystalline	NOUN
admet-1437	196	54	structure	structure	NOUN
admet-1437	196	55	can	can	AUX
admet-1437	196	56	no	no	ADV
admet-1437	196	57	longer	long	ADV
admet-1437	196	58	be	be	AUX
admet-1437	196	59	ignored	ignore	VERB
admet-1437	196	60	when	when	SCONJ
admet-1437	196	61	describing	describe	VERB
admet-1437	196	62	the	the	DET
admet-1437	196	63	solid	solid	ADJ
admet-1437	196	64	state	state	NOUN
admet-1437	196	65	of	of	ADP
admet-1437	196	66	the	the	DET
admet-1437	196	67	particles	particle	NOUN
admet-1437	196	68	[	[	X
admet-1437	196	69	82	82	NUM
admet-1437	196	70	]	]	PUNCT
admet-1437	196	71	.	.	PUNCT
admet-1437	197	1	in	in	ADP
admet-1437	197	2	general	general	ADJ
admet-1437	197	3	,	,	PUNCT
admet-1437	197	4	crystalline	crystalline	ADJ
admet-1437	197	5	particles	particle	NOUN
admet-1437	197	6	might	might	AUX
admet-1437	197	7	appear	appear	VERB
admet-1437	197	8	smooth	smooth	ADJ
admet-1437	197	9	by	by	ADP
admet-1437	197	10	light	light	NOUN
admet-1437	197	11	or	or	CCONJ
admet-1437	197	12	electron	electron	NOUN
admet-1437	197	13	microscopy	microscopy	NOUN
admet-1437	197	14	.	.	PUNCT
admet-1437	198	1	on	on	ADP
admet-1437	198	2	a	a	DET
admet-1437	198	3	molecular	molecular	ADJ
admet-1437	198	4	scale	scale	NOUN
admet-1437	198	5	,	,	PUNCT
admet-1437	198	6	however	however	ADV
admet-1437	198	7	,	,	PUNCT
admet-1437	198	8	every	every	DET
admet-1437	198	9	particle	particle	NOUN
admet-1437	198	10	will	will	AUX
admet-1437	198	11	show	show	VERB
admet-1437	198	12	a	a	DET
admet-1437	198	13	certain	certain	ADJ
admet-1437	198	14	amount	amount	NOUN
admet-1437	198	15	of	of	ADP
admet-1437	198	16	surface	surface	NOUN
admet-1437	198	17	rugosity	rugosity	NOUN
admet-1437	198	18	due	due	ADP
admet-1437	198	19	to	to	ADP
admet-1437	198	20	the	the	DET
admet-1437	198	21	growth	growth	NOUN
admet-1437	198	22	patterns	pattern	NOUN
admet-1437	198	23	of	of	ADP
admet-1437	198	24	the	the	DET
admet-1437	198	25	crystal	crystal	NOUN
admet-1437	198	26	.	.	PUNCT
admet-1437	199	1	this	this	PRON
admet-1437	199	2	might	might	AUX
admet-1437	199	3	lead	lead	VERB
admet-1437	199	4	to	to	ADP
admet-1437	199	5	steps	step	NOUN
admet-1437	199	6	or	or	CCONJ
admet-1437	199	7	valleys	valley	NOUN
admet-1437	199	8	on	on	ADP
admet-1437	199	9	the	the	DET
admet-1437	199	10	surface	surface	NOUN
admet-1437	199	11	of	of	ADP
admet-1437	199	12	a	a	DET
admet-1437	199	13	particle	particle	NOUN
admet-1437	199	14	.	.	PUNCT
admet-1437	200	1	in	in	ADP
admet-1437	200	2	addition	addition	NOUN
admet-1437	200	3	,	,	PUNCT
admet-1437	200	4	during	during	ADP
admet-1437	200	5	crystallization	crystallization	NOUN
admet-1437	200	6	,	,	PUNCT
admet-1437	200	7	imperfections	imperfection	NOUN
admet-1437	200	8	such	such	ADJ
admet-1437	200	9	as	as	ADP
admet-1437	200	10	surface	surface	NOUN
admet-1437	200	11	cracks	crack	NOUN
admet-1437	200	12	,	,	PUNCT
admet-1437	200	13	grain	grain	NOUN
admet-1437	200	14	boundaries	boundary	NOUN
admet-1437	200	15	between	between	ADP
admet-1437	200	16	crystallites	crystallite	NOUN
admet-1437	200	17	and	and	CCONJ
admet-1437	200	18	dislocations	dislocation	NOUN
admet-1437	200	19	can	can	AUX
admet-1437	200	20	also	also	ADV
admet-1437	200	21	create	create	VERB
admet-1437	200	22	a	a	DET
admet-1437	200	23	larger	large	ADJ
admet-1437	200	24	actual	actual	ADJ
admet-1437	200	25	surface	surface	NOUN
admet-1437	200	26	area	area	NOUN
admet-1437	200	27	,	,	PUNCT
admet-1437	200	28	see	see	VERB
admet-1437	200	29	figure	figure	NOUN
admet-1437	200	30	3(a	3(a	NUM
admet-1437	200	31	)	)	PUNCT
admet-1437	200	32	.	.	PUNCT
admet-1437	201	1	it	it	PRON
admet-1437	201	2	should	should	AUX
admet-1437	201	3	be	be	AUX
admet-1437	201	4	noted	note	VERB
admet-1437	201	5	that	that	SCONJ
admet-1437	201	6	some	some	PRON
admet-1437	201	7	of	of	ADP
admet-1437	201	8	these	these	DET
admet-1437	201	9	contributions	contribution	NOUN
admet-1437	201	10	might	might	AUX
admet-1437	201	11	not	not	PART
admet-1437	201	12	be	be	AUX
admet-1437	201	13	accessible	accessible	ADJ
admet-1437	201	14	,	,	PUNCT
admet-1437	201	15	with	with	ADP
admet-1437	201	16	every	every	DET
admet-1437	201	17	instrumental	instrumental	ADJ
admet-1437	201	18	technique	technique	NOUN
admet-1437	201	19	giving	give	VERB
admet-1437	201	20	rise	rise	NOUN
admet-1437	201	21	to	to	ADP
admet-1437	201	22	different	different	ADJ
admet-1437	201	23	estimates	estimate	NOUN
admet-1437	201	24	depending	depend	VERB
admet-1437	201	25	on	on	ADP
admet-1437	201	26	the	the	DET
admet-1437	201	27	chosen	choose	VERB
admet-1437	201	28	methodology	methodology	NOUN
admet-1437	201	29	.	.	PUNCT
admet-1437	202	1	further	far	ADV
admet-1437	202	2	,	,	PUNCT
admet-1437	202	3	noise	noise	NOUN
admet-1437	202	4	from	from	ADP
admet-1437	202	5	sample	sample	NOUN
admet-1437	202	6	containers	container	NOUN
admet-1437	202	7	and	and	CCONJ
admet-1437	202	8	inactive	inactive	ADJ
admet-1437	202	9	ingredients	ingredient	NOUN
admet-1437	202	10	in	in	ADP
admet-1437	202	11	the	the	DET
admet-1437	202	12	sample	sample	NOUN
admet-1437	202	13	will	will	AUX
admet-1437	202	14	generate	generate	VERB
admet-1437	202	15	a	a	DET
admet-1437	202	16	background	background	NOUN
admet-1437	202	17	signal	signal	NOUN
admet-1437	202	18	that	that	PRON
admet-1437	202	19	will	will	AUX
admet-1437	202	20	limit	limit	VERB
admet-1437	202	21	the	the	DET
admet-1437	202	22	sensitivity	sensitivity	NOUN
admet-1437	202	23	of	of	ADP
admet-1437	202	24	any	any	DET
admet-1437	202	25	method	method	NOUN
admet-1437	202	26	chosen	choose	VERB
admet-1437	202	27	.	.	PUNCT
admet-1437	203	1	figure	figure	VERB
admet-1437	203	2	3	3	NUM
admet-1437	203	3	.	.	PUNCT
admet-1437	204	1	(	(	PUNCT
admet-1437	204	2	a	a	X
admet-1437	204	3	)	)	PUNCT
admet-1437	204	4	schematic	schematic	ADJ
admet-1437	204	5	representation	representation	NOUN
admet-1437	204	6	of	of	ADP
admet-1437	204	7	a	a	DET
admet-1437	204	8	hypothetical	hypothetical	ADJ
admet-1437	204	9	crystal	crystal	NOUN
admet-1437	204	10	with	with	ADP
admet-1437	204	11	defects	defect	NOUN
admet-1437	204	12	.	.	PUNCT
admet-1437	205	1	(	(	PUNCT
admet-1437	205	2	b	b	X
admet-1437	205	3	)	)	PUNCT
admet-1437	205	4	intrinsic	intrinsic	ADJ
admet-1437	205	5	surface	surface	NOUN
admet-1437	205	6	amorphicity	amorphicity	NOUN
admet-1437	205	7	(	(	PUNCT
admet-1437	205	8	am	am	NOUN
admet-1437	205	9	)	)	PUNCT
admet-1437	205	10	of	of	ADP
admet-1437	205	11	a	a	DET
admet-1437	205	12	spherical	spherical	ADJ
admet-1437	205	13	particle	particle	NOUN
admet-1437	205	14	with	with	ADP
admet-1437	205	15	particle	particle	NOUN
admet-1437	205	16	size	size	NOUN
admet-1437	205	17	(	(	PUNCT
admet-1437	205	18	x	x	NOUN
admet-1437	205	19	)	)	PUNCT
admet-1437	205	20	and	and	CCONJ
admet-1437	205	21	depth	depth	NOUN
admet-1437	205	22	of	of	ADP
admet-1437	205	23	amorphous	amorphous	ADJ
admet-1437	205	24	surface	surface	NOUN
admet-1437	205	25	layer	layer	NOUN
admet-1437	205	26	in	in	ADP
admet-1437	205	27	a	a	DET
admet-1437	205	28	number	number	NOUN
admet-1437	205	29	of	of	ADP
admet-1437	205	30	layers	layer	NOUN
admet-1437	205	31	of	of	ADP
admet-1437	205	32	unit	unit	NOUN
admet-1437	205	33	cells	cell	NOUN
admet-1437	205	34	(	(	PUNCT
admet-1437	205	35	z	z	NOUN
admet-1437	205	36	)	)	PUNCT
admet-1437	205	37	.	.	PUNCT
admet-1437	206	1	crystalline	crystalline	PROPN
admet-1437	206	2	substances	substance	NOUN
admet-1437	206	3	show	show	VERB
admet-1437	206	4	a	a	DET
admet-1437	206	5	distinct	distinct	ADJ
admet-1437	206	6	xrpd	xrpd	NOUN
admet-1437	206	7	pattern	pattern	NOUN
admet-1437	206	8	.	.	PUNCT
admet-1437	207	1	however	however	ADV
admet-1437	207	2	,	,	PUNCT
admet-1437	207	3	by	by	ADP
admet-1437	207	4	definition	definition	NOUN
admet-1437	207	5	,	,	PUNCT
admet-1437	207	6	at	at	ADP
admet-1437	207	7	least	least	ADJ
admet-1437	207	8	the	the	DET
admet-1437	207	9	outermost	outermost	ADJ
admet-1437	207	10	molecular	molecular	ADJ
admet-1437	207	11	layer	layer	NOUN
admet-1437	207	12	on	on	ADP
admet-1437	207	13	the	the	DET
admet-1437	207	14	surface	surface	NOUN
admet-1437	207	15	of	of	ADP
admet-1437	207	16	a	a	DET
admet-1437	207	17	crystal	crystal	NOUN
admet-1437	207	18	,	,	PUNCT
admet-1437	207	19	see	see	VERB
admet-1437	207	20	figure	figure	NOUN
admet-1437	207	21	3(a	3(a	NUM
admet-1437	207	22	)	)	PUNCT
admet-1437	207	23	orange	orange	NOUN
admet-1437	207	24	color	color	NOUN
admet-1437	207	25	,	,	PUNCT
admet-1437	207	26	can	can	AUX
admet-1437	207	27	not	not	PART
admet-1437	207	28	exhibit	exhibit	VERB
admet-1437	207	29	the	the	DET
admet-1437	207	30	crystal	crystal	NOUN
admet-1437	207	31	lattice	lattice	NOUN
admet-1437	207	32	that	that	PRON
admet-1437	207	33	defines	define	VERB
admet-1437	207	34	the	the	DET
admet-1437	207	35	bulk	bulk	ADJ
admet-1437	207	36	crystal	crystal	NOUN
admet-1437	207	37	,	,	PUNCT
admet-1437	207	38	as	as	SCONJ
admet-1437	207	39	both	both	CCONJ
admet-1437	207	40	near	near	ADJ
admet-1437	207	41	and	and	CCONJ
admet-1437	207	42	far	far	ADJ
admet-1437	207	43	orders	order	NOUN
admet-1437	207	44	are	be	AUX
admet-1437	207	45	absent	absent	ADJ
admet-1437	207	46	at	at	ADP
admet-1437	207	47	the	the	DET
admet-1437	207	48	surface	surface	NOUN
admet-1437	207	49	.	.	PUNCT
admet-1437	208	1	it	it	PRON
admet-1437	208	2	can	can	AUX
admet-1437	208	3	be	be	AUX
admet-1437	208	4	assumed	assume	VERB
admet-1437	208	5	that	that	SCONJ
admet-1437	208	6	this	this	DET
admet-1437	208	7	layer	layer	NOUN
admet-1437	208	8	might	might	AUX
admet-1437	208	9	be	be	AUX
admet-1437	208	10	fully	fully	ADV
admet-1437	208	11	amorphous	amorphous	ADJ
admet-1437	208	12	.	.	PUNCT
admet-1437	209	1	similarly	similarly	ADV
admet-1437	209	2	,	,	PUNCT
admet-1437	209	3	the	the	DET
admet-1437	209	4	second	second	ADJ
admet-1437	209	5	,	,	PUNCT
admet-1437	209	6	and	and	CCONJ
admet-1437	209	7	maybe	maybe	ADV
admet-1437	209	8	the	the	DET
admet-1437	209	9	third	third	ADJ
admet-1437	209	10	,	,	PUNCT
admet-1437	209	11	outermost	outermost	ADJ
admet-1437	209	12	layers	layer	NOUN
admet-1437	209	13	do	do	AUX
admet-1437	209	14	not	not	PART
admet-1437	209	15	have	have	VERB
admet-1437	209	16	the	the	DET
admet-1437	209	17	same	same	ADJ
admet-1437	209	18	amount	amount	NOUN
admet-1437	209	19	of	of	ADP
admet-1437	209	20	far	far	ADJ
admet-1437	209	21	order	order	NOUN
admet-1437	209	22	as	as	ADP
admet-1437	209	23	unit	unit	NOUN
admet-1437	209	24	cells	cell	NOUN
admet-1437	209	25	deep	deep	ADV
admet-1437	209	26	inside	inside	ADP
admet-1437	209	27	the	the	DET
admet-1437	209	28	crystal	crystal	NOUN
admet-1437	209	29	,	,	PUNCT
admet-1437	209	30	see	see	VERB
admet-1437	209	31	figure	figure	NOUN
admet-1437	209	32	3(a	3(a	NUM
admet-1437	209	33	)	)	PUNCT
admet-1437	209	34	blue	blue	ADJ
admet-1437	209	35	color	color	NOUN
admet-1437	209	36	.	.	PUNCT
admet-1437	210	1	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	X
admet-1437	210	2	bonhoeffer	bonhoeffer	PROPN
admet-1437	210	3	et	et	PROPN
admet-1437	210	4	al	al	PROPN
admet-1437	210	5	.	.	PROPN
admet-1437	210	6	admet	admet	PROPN
admet-1437	210	7	&	&	CCONJ
admet-1437	210	8	dmpk	dmpk	PROPN
admet-1437	210	9	10(4	10(4	NUM
admet-1437	210	10	)	)	PUNCT
admet-1437	210	11	(	(	PUNCT
admet-1437	210	12	2022	2022	NUM
admet-1437	210	13	)	)	PUNCT
admet-1437	210	14	253	253	NUM
admet-1437	210	15	-	-	SYM
admet-1437	210	16	287	287	NUM
admet-1437	210	17	264	264	NUM
admet-1437	210	18	fine	fine	ADJ
admet-1437	210	19	particles	particle	NOUN
admet-1437	210	20	in	in	ADP
admet-1437	210	21	the	the	DET
admet-1437	210	22	lower	low	ADJ
admet-1437	210	23	micron	micron	NOUN
admet-1437	210	24	-	-	PUNCT
admet-1437	210	25	sized	sized	ADJ
admet-1437	210	26	or	or	CCONJ
admet-1437	210	27	even	even	ADV
admet-1437	210	28	submicron	submicron	NOUN
admet-1437	210	29	-	-	PUNCT
admet-1437	210	30	sized	sized	ADJ
admet-1437	210	31	range	range	NOUN
admet-1437	210	32	will	will	AUX
admet-1437	210	33	exhibit	exhibit	VERB
admet-1437	210	34	substantially	substantially	ADV
admet-1437	210	35	more	more	ADJ
admet-1437	210	36	relative	relative	ADJ
admet-1437	210	37	surface	surface	NOUN
admet-1437	210	38	area	area	NOUN
admet-1437	210	39	that	that	PRON
admet-1437	210	40	would	would	AUX
admet-1437	210	41	thereby	thereby	ADV
admet-1437	210	42	naturally	naturally	ADV
admet-1437	210	43	increase	increase	VERB
admet-1437	210	44	the	the	DET
admet-1437	210	45	amorphous	amorphous	ADJ
admet-1437	210	46	fraction	fraction	NOUN
admet-1437	210	47	of	of	ADP
admet-1437	210	48	the	the	DET
admet-1437	210	49	material	material	NOUN
admet-1437	210	50	,	,	PUNCT
admet-1437	210	51	even	even	ADV
admet-1437	210	52	in	in	ADP
admet-1437	210	53	the	the	DET
admet-1437	210	54	absence	absence	NOUN
admet-1437	210	55	of	of	ADP
admet-1437	210	56	further	further	ADJ
admet-1437	210	57	defects	defect	NOUN
admet-1437	210	58	.	.	PUNCT
admet-1437	211	1	estimating	estimate	VERB
admet-1437	211	2	this	this	DET
admet-1437	211	3	fraction	fraction	NOUN
admet-1437	211	4	would	would	AUX
admet-1437	211	5	therefore	therefore	ADV
admet-1437	211	6	predict	predict	VERB
admet-1437	211	7	a	a	DET
admet-1437	211	8	likely	likely	ADJ
admet-1437	211	9	minimum	minimum	NOUN
admet-1437	211	10	amount	amount	NOUN
admet-1437	211	11	of	of	ADP
admet-1437	211	12	amorphous	amorphous	ADJ
admet-1437	211	13	content	content	NOUN
admet-1437	211	14	that	that	PRON
admet-1437	211	15	could	could	AUX
admet-1437	211	16	be	be	AUX
admet-1437	211	17	expected	expect	VERB
admet-1437	211	18	depending	depend	VERB
admet-1437	211	19	on	on	ADP
admet-1437	211	20	the	the	DET
admet-1437	211	21	particle	particle	NOUN
admet-1437	211	22	size	size	NOUN
admet-1437	211	23	if	if	SCONJ
admet-1437	211	24	the	the	DET
admet-1437	211	25	surface	surface	NOUN
admet-1437	211	26	layer	layer	NOUN
admet-1437	211	27	were	be	AUX
admet-1437	211	28	truly	truly	ADV
admet-1437	211	29	fully	fully	ADV
admet-1437	211	30	amorphous	amorphous	ADJ
admet-1437	211	31	.	.	PUNCT
admet-1437	212	1	the	the	DET
admet-1437	212	2	amount	amount	NOUN
admet-1437	212	3	of	of	ADP
admet-1437	212	4	amorphous	amorphous	ADJ
admet-1437	212	5	surface	surface	NOUN
admet-1437	212	6	layer	layer	NOUN
admet-1437	212	7	(	(	PUNCT
admet-1437	212	8	am	be	AUX
admet-1437	212	9	)	)	PUNCT
admet-1437	212	10	in	in	ADP
admet-1437	212	11	relation	relation	NOUN
admet-1437	212	12	to	to	ADP
admet-1437	212	13	the	the	DET
admet-1437	212	14	particle	particle	NOUN
admet-1437	212	15	volume	volume	NOUN
admet-1437	212	16	can	can	AUX
admet-1437	212	17	be	be	AUX
admet-1437	212	18	calculated	calculate	VERB
admet-1437	212	19	using	use	VERB
admet-1437	212	20	a	a	DET
admet-1437	212	21	simplified	simplified	ADJ
admet-1437	212	22	core	core	NOUN
admet-1437	212	23	-	-	PUNCT
admet-1437	212	24	shell	shell	NOUN
admet-1437	212	25	model	model	NOUN
admet-1437	212	26	of	of	ADP
admet-1437	212	27	concentric	concentric	ADJ
admet-1437	212	28	spheres	sphere	NOUN
admet-1437	212	29	with	with	ADP
admet-1437	212	30	a	a	DET
admet-1437	212	31	shell	shell	ADJ
admet-1437	212	32	thickness	thickness	NOUN
admet-1437	212	33	corresponding	correspond	VERB
admet-1437	212	34	to	to	ADP
admet-1437	212	35	the	the	DET
admet-1437	212	36	number	number	NOUN
admet-1437	212	37	of	of	ADP
admet-1437	212	38	layers	layer	NOUN
admet-1437	212	39	of	of	ADP
admet-1437	212	40	unit	unit	NOUN
admet-1437	212	41	cells	cell	NOUN
admet-1437	212	42	according	accord	VERB
admet-1437	212	43	to	to	ADP
admet-1437	212	44	the	the	DET
admet-1437	212	45	expression	expression	NOUN
admet-1437	212	46	below	below	ADV
admet-1437	212	47	.	.	PUNCT
admet-1437	213	1	𝐴𝑀	𝐴𝑀	NOUN
admet-1437	213	2	=	=	SYM
admet-1437	213	3	𝑥3−(𝑥−2∙𝑍∙𝐷cell)3	𝑥3−(𝑥−2∙𝑍∙𝐷cell)3	PROPN
admet-1437	213	4	𝑥3	𝑥3	NOUN
admet-1437	213	5	(	(	PUNCT
admet-1437	213	6	6	6	NUM
admet-1437	213	7	)	)	PUNCT
admet-1437	213	8	whereby	whereby	SCONJ
admet-1437	213	9	dcell	dcell	NOUN
admet-1437	213	10	is	be	AUX
admet-1437	213	11	the	the	DET
admet-1437	213	12	diameter	diameter	NOUN
admet-1437	213	13	of	of	ADP
admet-1437	213	14	the	the	DET
admet-1437	213	15	crystallographic	crystallographic	ADJ
admet-1437	213	16	unit	unit	NOUN
admet-1437	213	17	cell	cell	NOUN
admet-1437	213	18	,	,	PUNCT
admet-1437	213	19	x	x	PUNCT
admet-1437	213	20	the	the	DET
admet-1437	213	21	particle	particle	NOUN
admet-1437	213	22	size	size	NOUN
admet-1437	213	23	,	,	PUNCT
admet-1437	213	24	and	and	CCONJ
admet-1437	213	25	z	z	NOUN
admet-1437	213	26	is	be	AUX
admet-1437	213	27	the	the	DET
admet-1437	213	28	depth	depth	NOUN
admet-1437	213	29	of	of	ADP
admet-1437	213	30	the	the	DET
admet-1437	213	31	amorphous	amorphous	ADJ
admet-1437	213	32	surface	surface	NOUN
admet-1437	213	33	layer	layer	NOUN
admet-1437	213	34	expressed	express	VERB
admet-1437	213	35	in	in	ADP
admet-1437	213	36	layers	layer	NOUN
admet-1437	213	37	of	of	ADP
admet-1437	213	38	unit	unit	NOUN
admet-1437	213	39	cells	cell	NOUN
admet-1437	213	40	.	.	PUNCT
admet-1437	214	1	using	use	VERB
admet-1437	214	2	the	the	DET
admet-1437	214	3	volume	volume	NOUN
admet-1437	214	4	of	of	ADP
admet-1437	214	5	the	the	DET
admet-1437	214	6	unit	unit	NOUN
admet-1437	214	7	cell	cell	NOUN
admet-1437	214	8	vcell	vcell	PROPN
admet-1437	214	9	,	,	PUNCT
admet-1437	214	10	which	which	PRON
admet-1437	214	11	can	can	AUX
admet-1437	214	12	be	be	AUX
admet-1437	214	13	calculated	calculate	VERB
admet-1437	214	14	using	use	VERB
admet-1437	214	15	the	the	DET
admet-1437	214	16	generalized	generalized	ADJ
admet-1437	214	17	expression	expression	NOUN
admet-1437	214	18	:	:	PUNCT
admet-1437	215	1	𝑉cell	𝑉cell	PROPN
admet-1437	215	2	=	=	PUNCT
admet-1437	216	1	𝑎	𝑎	X
admet-1437	216	2	∙	∙	PROPN
admet-1437	216	3	𝑏	𝑏	ADP
admet-1437	216	4	∙	∙	PROPN
admet-1437	216	5	𝑐	𝑐	PROPN
admet-1437	216	6	∙	∙	PROPN
admet-1437	216	7	√(1	√(1	NOUN
admet-1437	216	8	−	−	PROPN
admet-1437	216	9	cos2𝛼	cos2𝛼	NOUN
admet-1437	216	10	−	−	X
admet-1437	216	11	cos2𝛽	cos2𝛽	NOUN
admet-1437	216	12	−	−	PROPN
admet-1437	216	13	cos2𝛾	cos2𝛾	PROPN
admet-1437	216	14	)	)	PUNCT
admet-1437	217	1	+	+	CCONJ
admet-1437	217	2	2	2	NUM
admet-1437	217	3	∙	∙	PROPN
admet-1437	217	4	(	(	PUNCT
admet-1437	217	5	cos𝛼	cos𝛼	NOUN
admet-1437	217	6	∗	∗	VERB
admet-1437	217	7	cos𝛽	cos𝛽	PROPN
admet-1437	217	8	∗	∗	NOUN
admet-1437	217	9	cos𝛾	cos𝛾	NOUN
admet-1437	217	10	)	)	PUNCT
admet-1437	217	11	(	(	PUNCT
admet-1437	217	12	7	7	X
admet-1437	217	13	)	)	PUNCT
admet-1437	217	14	whereby	whereby	SCONJ
admet-1437	217	15	a	a	DET
admet-1437	217	16	,	,	PUNCT
admet-1437	217	17	b	b	NOUN
admet-1437	217	18	and	and	CCONJ
admet-1437	217	19	c	c	PROPN
admet-1437	217	20	are	be	AUX
admet-1437	217	21	the	the	DET
admet-1437	217	22	lengths	length	NOUN
admet-1437	217	23	of	of	ADP
admet-1437	217	24	the	the	DET
admet-1437	217	25	unit	unit	NOUN
admet-1437	217	26	cell	cell	NOUN
admet-1437	217	27	axes	axis	NOUN
admet-1437	217	28	and	and	CCONJ
admet-1437	217	29	α	α	NOUN
admet-1437	217	30	,	,	PUNCT
admet-1437	217	31	𝛽	𝛽	PROPN
admet-1437	217	32	and	and	CCONJ
admet-1437	217	33	γ	γ	NOUN
admet-1437	217	34	are	be	AUX
admet-1437	217	35	the	the	DET
admet-1437	217	36	respective	respective	ADJ
admet-1437	217	37	angles	angle	NOUN
admet-1437	217	38	.	.	PUNCT
admet-1437	218	1	the	the	DET
admet-1437	218	2	small	small	ADJ
admet-1437	218	3	average	average	ADJ
admet-1437	218	4	particle	particle	NOUN
admet-1437	218	5	size	size	NOUN
admet-1437	218	6	and	and	CCONJ
admet-1437	218	7	the	the	DET
admet-1437	218	8	significantly	significantly	ADV
admet-1437	218	9	rounded	rounded	ADJ
admet-1437	218	10	edges	edge	NOUN
admet-1437	218	11	of	of	ADP
admet-1437	218	12	individual	individual	ADJ
admet-1437	218	13	particles	particle	NOUN
admet-1437	218	14	justify	justify	VERB
admet-1437	218	15	the	the	DET
admet-1437	218	16	approximation	approximation	NOUN
admet-1437	218	17	of	of	ADP
admet-1437	218	18	spherical	spherical	ADJ
admet-1437	218	19	particle	particle	NOUN
admet-1437	218	20	morphology	morphology	NOUN
admet-1437	218	21	.	.	PUNCT
admet-1437	219	1	table	table	NOUN
admet-1437	219	2	3	3	NUM
admet-1437	219	3	shows	show	VERB
admet-1437	219	4	the	the	DET
admet-1437	219	5	estimated	estimate	VERB
admet-1437	219	6	percentage	percentage	NOUN
admet-1437	219	7	of	of	ADP
admet-1437	219	8	the	the	DET
admet-1437	219	9	intrinsic	intrinsic	ADJ
admet-1437	219	10	amorphous	amorphous	ADJ
admet-1437	219	11	surface	surface	NOUN
admet-1437	219	12	for	for	ADP
admet-1437	219	13	several	several	ADJ
admet-1437	219	14	relevant	relevant	ADJ
admet-1437	219	15	particle	particle	NOUN
admet-1437	219	16	sizes	size	NOUN
admet-1437	219	17	and	and	CCONJ
admet-1437	219	18	layer	layer	NOUN
admet-1437	219	19	depths	depth	NOUN
admet-1437	219	20	.	.	PUNCT
admet-1437	220	1	it	it	PRON
admet-1437	220	2	can	can	AUX
admet-1437	220	3	be	be	AUX
admet-1437	220	4	seen	see	VERB
admet-1437	220	5	that	that	SCONJ
admet-1437	220	6	for	for	ADP
admet-1437	220	7	coarse	coarse	ADJ
admet-1437	220	8	particles	particle	NOUN
admet-1437	220	9	,	,	PUNCT
admet-1437	220	10	assumed	assume	VERB
admet-1437	220	11	to	to	PART
admet-1437	220	12	have	have	VERB
admet-1437	220	13	a	a	DET
admet-1437	220	14	particle	particle	NOUN
admet-1437	220	15	size	size	NOUN
admet-1437	220	16	of	of	ADP
admet-1437	220	17	100	100	NUM
admet-1437	220	18	µm	µm	NOUN
admet-1437	220	19	,	,	PUNCT
admet-1437	220	20	the	the	DET
admet-1437	220	21	intrinsic	intrinsic	ADJ
admet-1437	220	22	amorphous	amorphous	ADJ
admet-1437	220	23	surface	surface	NOUN
admet-1437	220	24	layer	layer	NOUN
admet-1437	220	25	percentage	percentage	NOUN
admet-1437	220	26	is	be	AUX
admet-1437	220	27	negligible	negligible	ADJ
admet-1437	220	28	,	,	PUNCT
admet-1437	220	29	even	even	ADV
admet-1437	220	30	at	at	ADP
admet-1437	220	31	a	a	DET
admet-1437	220	32	depth	depth	NOUN
admet-1437	220	33	of	of	ADP
admet-1437	220	34	three	three	NUM
admet-1437	220	35	layers	layer	NOUN
admet-1437	220	36	.	.	PUNCT
admet-1437	221	1	for	for	ADP
admet-1437	221	2	particle	particle	NOUN
admet-1437	221	3	sizes	size	NOUN
admet-1437	221	4	between	between	ADP
admet-1437	221	5	1	1	NUM
admet-1437	221	6	and	and	CCONJ
admet-1437	221	7	3	3	NUM
admet-1437	221	8	µm	µm	NOUN
admet-1437	221	9	,	,	PUNCT
admet-1437	221	10	the	the	DET
admet-1437	221	11	intrinsic	intrinsic	ADJ
admet-1437	221	12	surface	surface	NOUN
admet-1437	221	13	amorphicity	amorphicity	NOUN
admet-1437	221	14	is	be	AUX
admet-1437	221	15	estimated	estimate	VERB
admet-1437	221	16	to	to	PART
admet-1437	221	17	be	be	AUX
admet-1437	221	18	not	not	PART
admet-1437	221	19	more	more	ADJ
admet-1437	221	20	than	than	ADP
admet-1437	221	21	2	2	NUM
admet-1437	221	22	%	%	NOUN
admet-1437	221	23	,	,	PUNCT
admet-1437	221	24	likely	likely	ADV
admet-1437	221	25	below	below	ADP
admet-1437	221	26	the	the	DET
admet-1437	221	27	limit	limit	NOUN
admet-1437	221	28	of	of	ADP
admet-1437	221	29	detection	detection	NOUN
admet-1437	221	30	with	with	ADP
admet-1437	221	31	state	state	NOUN
admet-1437	221	32	-	-	PUNCT
admet-1437	221	33	of	of	ADP
admet-1437	221	34	-	-	PUNCT
admet-1437	221	35	the	the	DET
admet-1437	221	36	-	-	PUNCT
admet-1437	221	37	art	art	NOUN
admet-1437	221	38	equipment	equipment	NOUN
admet-1437	221	39	.	.	PUNCT
admet-1437	222	1	table	table	NOUN
admet-1437	222	2	3	3	NUM
admet-1437	222	3	.	.	PUNCT
admet-1437	222	4	estimated	estimate	VERB
admet-1437	222	5	relative	relative	ADJ
admet-1437	222	6	amount	amount	NOUN
admet-1437	222	7	of	of	ADP
admet-1437	222	8	the	the	DET
admet-1437	222	9	amorphous	amorphous	ADJ
admet-1437	222	10	content	content	NOUN
admet-1437	222	11	(	(	PUNCT
admet-1437	222	12	am	be	AUX
admet-1437	222	13	)	)	PUNCT
admet-1437	222	14	for	for	ADP
admet-1437	222	15	different	different	ADJ
admet-1437	222	16	particle	particle	NOUN
admet-1437	222	17	sizes	size	NOUN
admet-1437	222	18	(	(	PUNCT
admet-1437	222	19	x	x	NOUN
admet-1437	222	20	)	)	PUNCT
admet-1437	222	21	and	and	CCONJ
admet-1437	222	22	a	a	DET
admet-1437	222	23	different	different	ADJ
admet-1437	222	24	number	number	NOUN
admet-1437	222	25	of	of	ADP
admet-1437	222	26	layers	layer	NOUN
admet-1437	222	27	of	of	ADP
admet-1437	222	28	unit	unit	NOUN
admet-1437	222	29	cells	cell	NOUN
admet-1437	222	30	(	(	PUNCT
admet-1437	222	31	z	z	NOUN
admet-1437	222	32	)	)	PUNCT
admet-1437	222	33	.	.	PUNCT
admet-1437	223	1	particle	particle	NOUN
admet-1437	223	2	size	size	NOUN
admet-1437	223	3	/	/	SYM
admet-1437	223	4	nm	nm	ADV
admet-1437	223	5	amorphous	amorphous	ADJ
admet-1437	223	6	content	content	NOUN
admet-1437	223	7	/	/	SYM
admet-1437	223	8	%	%	NOUN
admet-1437	223	9	z=1	z=1	PUNCT
admet-1437	223	10	z=2	z=2	PUNCT
admet-1437	224	1	z=3	z=3	NUM
admet-1437	224	2	20	20	NUM
admet-1437	224	3	28.5	28.5	NUM
admet-1437	224	4	51.0	51.0	NUM
admet-1437	224	5	68.1	68.1	NUM
admet-1437	224	6	50	50	NUM
admet-1437	224	7	12.2	12.2	NUM
admet-1437	224	8	23.3	23.3	NUM
admet-1437	224	9	33.4	33.4	NUM
admet-1437	224	10	100	100	NUM
admet-1437	224	11	6.2	6.2	NUM
admet-1437	224	12	12.2	12.2	NUM
admet-1437	224	13	17.8	17.8	NUM
admet-1437	224	14	200	200	NUM
admet-1437	224	15	3.1	3.1	NUM
admet-1437	224	16	6.2	6.2	NUM
admet-1437	224	17	9.2	9.2	NUM
admet-1437	224	18	1000	1000	NUM
admet-1437	224	19	0.6	0.6	NUM
admet-1437	224	20	1.3	1.3	NUM
admet-1437	224	21	1.9	1.9	NUM
admet-1437	224	22	3000	3000	NUM
admet-1437	224	23	0.2	0.2	NUM
admet-1437	224	24	0.4	0.4	NUM
admet-1437	224	25	0.6	0.6	NUM
admet-1437	224	26	100000	100000	NUM
admet-1437	224	27	0.01	0.01	NUM
admet-1437	224	28	0.01	0.01	NUM
admet-1437	224	29	0.02	0.02	NUM
admet-1437	224	30	for	for	ADP
admet-1437	224	31	particles	particle	NOUN
admet-1437	224	32	with	with	ADP
admet-1437	224	33	a	a	DET
admet-1437	224	34	size	size	NOUN
admet-1437	224	35	below	below	ADP
admet-1437	224	36	about	about	ADP
admet-1437	224	37	200	200	NUM
admet-1437	224	38	nm	nm	NOUN
admet-1437	225	1	,	,	PUNCT
admet-1437	225	2	the	the	DET
admet-1437	225	3	intrinsic	intrinsic	ADJ
admet-1437	225	4	amorphous	amorphous	ADJ
admet-1437	225	5	surface	surface	NOUN
admet-1437	225	6	contribution	contribution	NOUN
admet-1437	225	7	is	be	AUX
admet-1437	225	8	estimated	estimate	VERB
admet-1437	225	9	to	to	PART
admet-1437	225	10	become	become	VERB
admet-1437	225	11	detectable	detectable	ADJ
admet-1437	225	12	and	and	CCONJ
admet-1437	225	13	quantifiable	quantifiable	ADJ
admet-1437	225	14	with	with	ADP
admet-1437	225	15	state	state	NOUN
admet-1437	225	16	-	-	PUNCT
admet-1437	225	17	of	of	ADP
admet-1437	225	18	-	-	PUNCT
admet-1437	225	19	the	the	DET
admet-1437	225	20	-	-	PUNCT
admet-1437	225	21	art	art	NOUN
admet-1437	225	22	equipment	equipment	NOUN
admet-1437	225	23	.	.	PUNCT
admet-1437	226	1	on	on	ADP
admet-1437	226	2	average	average	ADJ
admet-1437	226	3	,	,	PUNCT
admet-1437	226	4	between	between	ADP
admet-1437	226	5	6.2	6.2	NUM
admet-1437	226	6	to	to	PART
admet-1437	226	7	17.8	17.8	NUM
admet-1437	226	8	%	%	NOUN
admet-1437	226	9	of	of	ADP
admet-1437	226	10	amorphous	amorphous	ADJ
admet-1437	226	11	content	content	NOUN
admet-1437	226	12	due	due	ADP
admet-1437	226	13	to	to	ADP
admet-1437	226	14	the	the	DET
admet-1437	226	15	surface	surface	NOUN
admet-1437	226	16	layers	layer	NOUN
admet-1437	226	17	are	be	AUX
admet-1437	226	18	estimated	estimate	VERB
admet-1437	226	19	for	for	ADP
admet-1437	226	20	a	a	DET
admet-1437	226	21	100	100	NUM
admet-1437	226	22	nm	nm	ADJ
admet-1437	226	23	particle	particle	NOUN
admet-1437	226	24	.	.	PUNCT
admet-1437	227	1	ultrafine	ultrafine	ADJ
admet-1437	227	2	particles	particle	NOUN
admet-1437	227	3	of	of	ADP
admet-1437	227	4	20	20	NUM
admet-1437	227	5	nm	nm	NOUN
admet-1437	227	6	are	be	AUX
admet-1437	227	7	likely	likely	ADJ
admet-1437	227	8	to	to	PART
admet-1437	227	9	be	be	AUX
admet-1437	227	10	more	more	ADV
admet-1437	227	11	amorphous	amorphous	ADJ
admet-1437	227	12	than	than	ADP
admet-1437	227	13	crystalline	crystalline	NOUN
admet-1437	227	14	.	.	PUNCT
admet-1437	228	1	the	the	DET
admet-1437	228	2	relationship	relationship	NOUN
admet-1437	228	3	between	between	ADP
admet-1437	228	4	particle	particle	NOUN
admet-1437	228	5	size	size	NOUN
admet-1437	228	6	and	and	CCONJ
admet-1437	228	7	the	the	DET
admet-1437	228	8	intrinsic	intrinsic	ADJ
admet-1437	228	9	amorphous	amorphous	ADJ
admet-1437	228	10	surface	surface	NOUN
admet-1437	228	11	is	be	AUX
admet-1437	228	12	depicted	depict	VERB
admet-1437	228	13	in	in	ADP
admet-1437	228	14	figure	figure	NOUN
admet-1437	228	15	3(b	3(b	NUM
admet-1437	228	16	)	)	PUNCT
admet-1437	228	17	.	.	PUNCT
admet-1437	229	1	further	far	ADV
admet-1437	229	2	,	,	PUNCT
admet-1437	229	3	the	the	DET
admet-1437	229	4	inserts	insert	NOUN
admet-1437	229	5	visualize	visualize	VERB
admet-1437	229	6	the	the	DET
admet-1437	229	7	amorphous	amorphous	ADJ
admet-1437	229	8	layer	layer	NOUN
admet-1437	229	9	for	for	ADP
admet-1437	229	10	a	a	DET
admet-1437	229	11	few	few	ADJ
admet-1437	229	12	selected	select	VERB
admet-1437	229	13	particle	particle	NOUN
admet-1437	229	14	sizes	size	NOUN
admet-1437	229	15	and	and	CCONJ
admet-1437	229	16	layer	layer	NOUN
admet-1437	229	17	depths	depth	NOUN
admet-1437	229	18	.	.	PUNCT
admet-1437	230	1	transmission	transmission	NOUN
admet-1437	230	2	xrpd	xrpd	ADJ
admet-1437	230	3	experiments	experiment	NOUN
admet-1437	230	4	using	use	VERB
admet-1437	230	5	a	a	DET
admet-1437	230	6	glass	glass	NOUN
admet-1437	230	7	capillary	capillary	ADJ
admet-1437	230	8	were	be	AUX
admet-1437	230	9	tried	try	VERB
admet-1437	230	10	to	to	PART
admet-1437	230	11	quantify	quantify	VERB
admet-1437	230	12	the	the	DET
admet-1437	230	13	amorphous	amorphous	ADJ
admet-1437	230	14	content	content	NOUN
admet-1437	230	15	of	of	ADP
admet-1437	230	16	the	the	DET
admet-1437	230	17	nanocrystals	nanocrystal	NOUN
admet-1437	230	18	.	.	PUNCT
admet-1437	231	1	the	the	DET
admet-1437	231	2	glass	glass	NOUN
admet-1437	231	3	capillary	capillary	ADJ
admet-1437	231	4	and	and	CCONJ
admet-1437	231	5	the	the	DET
admet-1437	231	6	placebo	placebo	NOUN
admet-1437	231	7	create	create	VERB
admet-1437	231	8	a	a	DET
admet-1437	231	9	background	background	NOUN
admet-1437	231	10	signal	signal	NOUN
admet-1437	231	11	that	that	PRON
admet-1437	231	12	needs	need	VERB
admet-1437	231	13	to	to	PART
admet-1437	231	14	be	be	AUX
admet-1437	231	15	subtracted	subtract	VERB
admet-1437	231	16	.	.	PUNCT
admet-1437	232	1	it	it	PRON
admet-1437	232	2	was	be	AUX
admet-1437	232	3	assumed	assume	VERB
admet-1437	232	4	that	that	SCONJ
admet-1437	232	5	all	all	DET
admet-1437	232	6	glass	glass	NOUN
admet-1437	232	7	capillaries	capillary	NOUN
admet-1437	232	8	were	be	AUX
admet-1437	232	9	identical	identical	ADJ
admet-1437	232	10	and	and	CCONJ
admet-1437	232	11	that	that	SCONJ
admet-1437	232	12	the	the	DET
admet-1437	232	13	placebo	placebo	NOUN
admet-1437	232	14	solution	solution	NOUN
admet-1437	232	15	of	of	ADP
admet-1437	232	16	the	the	DET
admet-1437	232	17	stabilizers	stabilizer	NOUN
admet-1437	232	18	could	could	AUX
admet-1437	232	19	be	be	AUX
admet-1437	232	20	subtracted	subtract	VERB
admet-1437	232	21	from	from	ADP
admet-1437	232	22	the	the	DET
admet-1437	232	23	total	total	ADJ
admet-1437	232	24	signal	signal	NOUN
admet-1437	232	25	of	of	ADP
admet-1437	232	26	the	the	DET
admet-1437	232	27	suspension	suspension	NOUN
admet-1437	232	28	.	.	PUNCT
admet-1437	233	1	however	however	ADV
admet-1437	233	2	,	,	PUNCT
admet-1437	233	3	prior	prior	ADJ
admet-1437	233	4	investigations	investigation	NOUN
admet-1437	233	5	had	have	AUX
admet-1437	233	6	shown	show	VERB
admet-1437	233	7	that	that	DET
admet-1437	233	8	part	part	NOUN
admet-1437	233	9	or	or	CCONJ
admet-1437	233	10	all	all	PRON
admet-1437	233	11	of	of	ADP
admet-1437	233	12	the	the	DET
admet-1437	233	13	stabilizer	stabilizer	NOUN
admet-1437	233	14	interacts	interact	VERB
admet-1437	233	15	with	with	ADP
admet-1437	233	16	the	the	DET
admet-1437	233	17	surface	surface	NOUN
admet-1437	233	18	of	of	ADP
admet-1437	233	19	the	the	DET
admet-1437	233	20	wet	wet	ADJ
admet-1437	233	21	-	-	PUNCT
admet-1437	233	22	media	media	NOUN
admet-1437	233	23	milled	mill	VERB
admet-1437	233	24	particles	particle	NOUN
admet-1437	233	25	and	and	CCONJ
admet-1437	233	26	is	be	AUX
admet-1437	233	27	therefore	therefore	ADV
admet-1437	233	28	bound	bind	VERB
admet-1437	233	29	and	and	CCONJ
admet-1437	233	30	admet	admet	PROPN
admet-1437	233	31	&	&	CCONJ
admet-1437	233	32	dmpk	dmpk	PROPN
admet-1437	233	33	10(4	10(4	NUM
admet-1437	233	34	)	)	PUNCT
admet-1437	233	35	(	(	PUNCT
admet-1437	233	36	2022	2022	NUM
admet-1437	233	37	)	)	PUNCT
admet-1437	233	38	253	253	NUM
admet-1437	233	39	-	-	SYM
admet-1437	233	40	287	287	NUM
admet-1437	233	41	modeling	modeling	NOUN
admet-1437	233	42	of	of	ADP
admet-1437	233	43	drug	drug	NOUN
admet-1437	233	44	nanocrystals	nanocrystal	NOUN
admet-1437	233	45	dissolution	dissolution	NOUN
admet-1437	233	46	doi	doi	PROPN
admet-1437	233	47	:	:	PUNCT
admet-1437	233	48	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	233	49	265	265	NUM
admet-1437	233	50	no	no	ADV
admet-1437	233	51	longer	long	ADV
admet-1437	233	52	freely	freely	ADV
admet-1437	233	53	available	available	ADJ
admet-1437	233	54	in	in	ADP
admet-1437	233	55	the	the	DET
admet-1437	233	56	supernatant	supernatant	NOUN
admet-1437	233	57	solution	solution	NOUN
admet-1437	233	58	.	.	PUNCT
admet-1437	234	1	this	this	DET
admet-1437	234	2	bound	bind	VERB
admet-1437	234	3	amount	amount	NOUN
admet-1437	234	4	should	should	AUX
admet-1437	234	5	vary	vary	VERB
admet-1437	234	6	with	with	ADP
admet-1437	234	7	the	the	DET
admet-1437	234	8	particle	particle	NOUN
admet-1437	234	9	size	size	NOUN
admet-1437	234	10	,	,	PUNCT
admet-1437	234	11	but	but	CCONJ
admet-1437	234	12	it	it	PRON
admet-1437	234	13	was	be	AUX
admet-1437	234	14	assumed	assume	VERB
admet-1437	234	15	that	that	SCONJ
admet-1437	234	16	the	the	DET
admet-1437	234	17	variation	variation	NOUN
admet-1437	234	18	between	between	ADP
admet-1437	234	19	the	the	DET
admet-1437	234	20	individual	individual	ADJ
admet-1437	234	21	batches	batch	NOUN
admet-1437	234	22	was	be	AUX
admet-1437	234	23	small	small	ADJ
admet-1437	234	24	.	.	PUNCT
admet-1437	235	1	to	to	PART
admet-1437	235	2	further	far	ADV
admet-1437	235	3	investigate	investigate	VERB
admet-1437	235	4	this	this	DET
admet-1437	235	5	effect	effect	NOUN
admet-1437	235	6	,	,	PUNCT
admet-1437	235	7	a	a	DET
admet-1437	235	8	suspension	suspension	NOUN
admet-1437	235	9	with	with	ADP
admet-1437	235	10	the	the	DET
admet-1437	235	11	smallest	small	ADJ
admet-1437	235	12	mean	mean	ADJ
admet-1437	235	13	particle	particle	NOUN
admet-1437	235	14	size	size	NOUN
admet-1437	235	15	was	be	AUX
admet-1437	235	16	centrifuged	centrifuge	VERB
admet-1437	235	17	using	use	VERB
admet-1437	235	18	an	an	DET
admet-1437	235	19	ultracentrifuge	ultracentrifuge	NOUN
admet-1437	235	20	generating	generate	VERB
admet-1437	235	21	a	a	DET
admet-1437	235	22	particle	particle	NOUN
admet-1437	235	23	-	-	PUNCT
admet-1437	235	24	free	free	ADJ
admet-1437	235	25	supernatant	supernatant	NOUN
admet-1437	235	26	solution	solution	NOUN
admet-1437	235	27	.	.	PUNCT
admet-1437	236	1	this	this	DET
admet-1437	236	2	supernatant	supernatant	NOUN
admet-1437	236	3	showed	show	VERB
admet-1437	236	4	a	a	DET
admet-1437	236	5	low	low	ADJ
admet-1437	236	6	xrpd	xrpd	NOUN
admet-1437	236	7	absorption	absorption	NOUN
admet-1437	236	8	across	across	ADP
admet-1437	236	9	the	the	DET
admet-1437	236	10	angular	angular	ADJ
admet-1437	236	11	range	range	NOUN
admet-1437	236	12	,	,	PUNCT
admet-1437	236	13	showing	show	VERB
admet-1437	236	14	that	that	SCONJ
admet-1437	236	15	most	most	ADJ
admet-1437	236	16	of	of	ADP
admet-1437	236	17	the	the	DET
admet-1437	236	18	stabilizer	stabilizer	NOUN
admet-1437	236	19	is	be	AUX
admet-1437	236	20	indeed	indeed	ADV
admet-1437	236	21	absorbed	absorb	VERB
admet-1437	236	22	to	to	ADP
admet-1437	236	23	the	the	DET
admet-1437	236	24	surface	surface	NOUN
admet-1437	236	25	of	of	ADP
admet-1437	236	26	the	the	DET
admet-1437	236	27	particles	particle	NOUN
admet-1437	236	28	in	in	ADP
admet-1437	236	29	suspension	suspension	NOUN
admet-1437	236	30	(	(	PUNCT
admet-1437	236	31	data	datum	NOUN
admet-1437	236	32	not	not	PART
admet-1437	236	33	shown	show	VERB
admet-1437	236	34	)	)	PUNCT
admet-1437	236	35	.	.	PUNCT
admet-1437	237	1	the	the	DET
admet-1437	237	2	centrifuged	centrifuged	ADJ
admet-1437	237	3	placebo	placebo	NOUN
admet-1437	237	4	solution	solution	NOUN
admet-1437	237	5	was	be	AUX
admet-1437	237	6	used	use	VERB
admet-1437	237	7	for	for	ADP
admet-1437	237	8	the	the	DET
admet-1437	237	9	background	background	NOUN
admet-1437	237	10	correction	correction	NOUN
admet-1437	237	11	for	for	ADP
admet-1437	237	12	all	all	DET
admet-1437	237	13	suspensions	suspension	NOUN
admet-1437	237	14	.	.	PUNCT
admet-1437	238	1	figure	figure	VERB
admet-1437	238	2	4	4	NUM
admet-1437	238	3	.	.	PUNCT
admet-1437	238	4	transmission	transmission	NOUN
admet-1437	238	5	xrpd	xrpd	PROPN
admet-1437	238	6	patterns	pattern	NOUN
admet-1437	238	7	at	at	ADP
admet-1437	238	8	selected	select	VERB
admet-1437	238	9	diffraction	diffraction	NOUN
admet-1437	238	10	angles	angle	NOUN
admet-1437	238	11	for	for	ADP
admet-1437	238	12	experiment	experiment	NOUN
admet-1437	238	13	no.1	no.1	VERB
admet-1437	238	14	and	and	CCONJ
admet-1437	238	15	6	6	NUM
admet-1437	238	16	to	to	PART
admet-1437	238	17	8	8	NUM
admet-1437	238	18	with	with	ADP
admet-1437	238	19	particle	particle	NOUN
admet-1437	238	20	size	size	NOUN
admet-1437	238	21	x50,3	x50,3	PROPN
admet-1437	238	22	of	of	ADP
admet-1437	238	23	2443	2443	NUM
admet-1437	238	24	,	,	PUNCT
admet-1437	238	25	93	93	NUM
admet-1437	238	26	,	,	PUNCT
admet-1437	238	27	90	90	NUM
admet-1437	238	28	and	and	CCONJ
admet-1437	238	29	79	79	NUM
admet-1437	238	30	nm	nm	NOUN
admet-1437	238	31	.	.	PUNCT
admet-1437	239	1	(	(	PUNCT
admet-1437	239	2	a	a	X
admet-1437	239	3	)	)	PUNCT
admet-1437	239	4	transmission	transmission	NOUN
admet-1437	239	5	xrpd	xrpd	NOUN
admet-1437	239	6	pattern	pattern	NOUN
admet-1437	239	7	between	between	ADP
admet-1437	239	8	11	11	NUM
admet-1437	239	9	°	°	NUM
admet-1437	239	10	and	and	CCONJ
admet-1437	239	11	15	15	NUM
admet-1437	239	12	°	°	NOUN
admet-1437	239	13	2	2	NUM
admet-1437	239	14	θ	θ	NOUN
admet-1437	239	15	.	.	PUNCT
admet-1437	240	1	(	(	PUNCT
admet-1437	240	2	b	b	NOUN
admet-1437	240	3	)	)	PUNCT
admet-1437	240	4	transmission	transmission	NOUN
admet-1437	240	5	xrpd	xrpd	NOUN
admet-1437	240	6	pattern	pattern	NOUN
admet-1437	240	7	between	between	ADP
admet-1437	240	8	30	30	NUM
admet-1437	240	9	°	°	NUM
admet-1437	240	10	and	and	CCONJ
admet-1437	240	11	35	35	NUM
admet-1437	240	12	°	°	NUM
admet-1437	240	13	2θ	2θ	NUM
admet-1437	240	14	.	.	PUNCT
admet-1437	241	1	scrutinizing	scrutinize	VERB
admet-1437	241	2	the	the	DET
admet-1437	241	3	xrpd	xrpd	PROPN
admet-1437	241	4	patterns	pattern	NOUN
admet-1437	241	5	in	in	ADP
admet-1437	241	6	the	the	DET
admet-1437	241	7	range	range	NOUN
admet-1437	241	8	of	of	ADP
admet-1437	241	9	11	11	NUM
admet-1437	241	10	to	to	PART
admet-1437	241	11	15	15	NUM
admet-1437	241	12	°	°	NOUN
admet-1437	241	13	2θ	2θ	NUM
admet-1437	241	14	shows	show	VERB
admet-1437	241	15	that	that	SCONJ
admet-1437	241	16	the	the	DET
admet-1437	241	17	suspension	suspension	NOUN
admet-1437	241	18	containing	contain	VERB
admet-1437	241	19	the	the	DET
admet-1437	241	20	micron	micron	NOUN
admet-1437	241	21	-	-	PUNCT
admet-1437	241	22	sized	sized	ADJ
admet-1437	241	23	particles	particle	NOUN
admet-1437	241	24	has	have	VERB
admet-1437	241	25	a	a	DET
admet-1437	241	26	significantly	significantly	ADV
admet-1437	241	27	more	more	ADV
admet-1437	241	28	intense	intense	ADJ
admet-1437	241	29	reflection	reflection	NOUN
admet-1437	241	30	signal	signal	NOUN
admet-1437	241	31	than	than	ADP
admet-1437	241	32	the	the	DET
admet-1437	241	33	nanocrystal	nanocrystal	ADJ
admet-1437	241	34	particles	particle	NOUN
admet-1437	241	35	,	,	PUNCT
admet-1437	241	36	see	see	VERB
admet-1437	241	37	figure	figure	NOUN
admet-1437	241	38	4(a	4(a	NUM
admet-1437	241	39	)	)	PUNCT
admet-1437	241	40	.	.	PUNCT
admet-1437	242	1	indeed	indeed	ADV
admet-1437	242	2	,	,	PUNCT
admet-1437	242	3	a	a	DET
admet-1437	242	4	small	small	ADJ
admet-1437	242	5	diffraction	diffraction	NOUN
admet-1437	242	6	peak	peak	NOUN
admet-1437	242	7	at	at	ADP
admet-1437	242	8	11.7	11.7	NUM
admet-1437	242	9	°	°	NOUN
admet-1437	242	10	is	be	AUX
admet-1437	242	11	still	still	ADV
admet-1437	242	12	visible	visible	ADJ
admet-1437	242	13	that	that	SCONJ
admet-1437	242	14	usually	usually	ADV
admet-1437	242	15	can	can	AUX
admet-1437	242	16	only	only	ADV
admet-1437	242	17	be	be	AUX
admet-1437	242	18	seen	see	VERB
admet-1437	242	19	in	in	ADP
admet-1437	242	20	a	a	DET
admet-1437	242	21	fully	fully	ADV
admet-1437	242	22	crystalline	crystalline	ADJ
admet-1437	242	23	material	material	NOUN
admet-1437	242	24	.	.	PUNCT
admet-1437	243	1	for	for	ADP
admet-1437	243	2	the	the	DET
admet-1437	243	3	nanocrystal	nanocrystal	ADJ
admet-1437	243	4	particles	particle	NOUN
admet-1437	243	5	of	of	ADP
admet-1437	243	6	x50,3	x50,3	PROPN
admet-1437	243	7	of	of	ADP
admet-1437	243	8	79	79	NUM
admet-1437	243	9	,	,	PUNCT
admet-1437	243	10	90	90	NUM
admet-1437	243	11	and	and	CCONJ
admet-1437	243	12	93	93	NUM
admet-1437	243	13	nm	nm	NOUN
admet-1437	243	14	,	,	PUNCT
admet-1437	243	15	the	the	DET
admet-1437	243	16	intensity	intensity	NOUN
admet-1437	243	17	of	of	ADP
admet-1437	243	18	the	the	DET
admet-1437	243	19	peak	peak	NOUN
admet-1437	243	20	in	in	ADP
admet-1437	243	21	this	this	DET
admet-1437	243	22	range	range	NOUN
admet-1437	243	23	diminishes	diminish	VERB
admet-1437	243	24	with	with	ADP
admet-1437	243	25	their	their	PRON
admet-1437	243	26	respective	respective	ADJ
admet-1437	243	27	particle	particle	NOUN
admet-1437	243	28	size	size	NOUN
admet-1437	243	29	,	,	PUNCT
admet-1437	243	30	and	and	CCONJ
admet-1437	243	31	a	a	DET
admet-1437	243	32	visible	visible	ADJ
admet-1437	243	33	peak	peak	NOUN
admet-1437	243	34	broadening	broaden	VERB
admet-1437	243	35	compared	compare	VERB
admet-1437	243	36	to	to	ADP
admet-1437	243	37	the	the	DET
admet-1437	243	38	micronsized	micronsized	ADJ
admet-1437	243	39	particles	particle	NOUN
admet-1437	243	40	can	can	AUX
admet-1437	243	41	be	be	AUX
admet-1437	243	42	seen	see	VERB
admet-1437	243	43	.	.	PUNCT
admet-1437	244	1	at	at	ADP
admet-1437	244	2	higher	high	ADJ
admet-1437	244	3	2θ	2θ	NUM
admet-1437	244	4	angles	angle	NOUN
admet-1437	244	5	,	,	PUNCT
admet-1437	244	6	the	the	DET
admet-1437	244	7	micron	micron	NOUN
admet-1437	244	8	-	-	PUNCT
admet-1437	244	9	sized	sized	ADJ
admet-1437	244	10	particles	particle	NOUN
admet-1437	244	11	again	again	ADV
admet-1437	244	12	show	show	VERB
admet-1437	244	13	the	the	DET
admet-1437	244	14	highest	high	ADJ
admet-1437	244	15	residual	residual	ADJ
admet-1437	244	16	peak	peak	NOUN
admet-1437	244	17	intensity	intensity	NOUN
admet-1437	244	18	and	and	CCONJ
admet-1437	244	19	a	a	DET
admet-1437	244	20	slightly	slightly	ADV
admet-1437	244	21	smaller	small	ADJ
admet-1437	244	22	halo	halo	NOUN
admet-1437	244	23	intensity	intensity	NOUN
admet-1437	244	24	,	,	PUNCT
admet-1437	244	25	while	while	SCONJ
admet-1437	244	26	the	the	DET
admet-1437	244	27	other	other	ADJ
admet-1437	244	28	nanocrystal	nanocrystal	ADJ
admet-1437	244	29	particles	particle	NOUN
admet-1437	244	30	appear	appear	VERB
admet-1437	244	31	to	to	PART
admet-1437	244	32	be	be	AUX
admet-1437	244	33	identical	identical	ADJ
admet-1437	244	34	.	.	PUNCT
admet-1437	245	1	at	at	ADP
admet-1437	245	2	high	high	ADJ
admet-1437	245	3	diffraction	diffraction	NOUN
admet-1437	245	4	angles	angle	NOUN
admet-1437	245	5	,	,	PUNCT
admet-1437	245	6	i.e.	i.e.	X
admet-1437	245	7	,	,	PUNCT
admet-1437	245	8	30	30	NUM
admet-1437	245	9	°	°	NUM
admet-1437	245	10	to	to	ADP
admet-1437	245	11	35	35	NUM
admet-1437	245	12	°	°	NOUN
admet-1437	245	13	2θ	2θ	NUM
admet-1437	245	14	,	,	PUNCT
admet-1437	245	15	some	some	DET
admet-1437	245	16	patterns	pattern	NOUN
admet-1437	245	17	show	show	VERB
admet-1437	245	18	a	a	DET
admet-1437	245	19	residual	residual	ADJ
admet-1437	245	20	amorphous	amorphous	ADJ
admet-1437	245	21	halo	halo	NOUN
admet-1437	245	22	after	after	ADP
admet-1437	245	23	subtraction	subtraction	NOUN
admet-1437	245	24	of	of	ADP
admet-1437	245	25	the	the	DET
admet-1437	245	26	placebo	placebo	NOUN
admet-1437	245	27	,	,	PUNCT
admet-1437	245	28	indicating	indicate	VERB
admet-1437	245	29	a	a	DET
admet-1437	245	30	significant	significant	ADJ
admet-1437	245	31	degree	degree	NOUN
admet-1437	245	32	of	of	ADP
admet-1437	245	33	amorphous	amorphous	ADJ
admet-1437	245	34	content	content	NOUN
admet-1437	245	35	in	in	ADP
admet-1437	245	36	the	the	DET
admet-1437	245	37	nanocrystals	nanocrystal	NOUN
admet-1437	245	38	.	.	PUNCT
admet-1437	246	1	for	for	ADP
admet-1437	246	2	the	the	DET
admet-1437	246	3	quantification	quantification	NOUN
admet-1437	246	4	of	of	ADP
admet-1437	246	5	the	the	DET
admet-1437	246	6	amorphous	amorphous	ADJ
admet-1437	246	7	content	content	NOUN
admet-1437	246	8	,	,	PUNCT
admet-1437	246	9	a	a	DET
admet-1437	246	10	fully	fully	ADV
admet-1437	246	11	crystalline	crystalline	NOUN
admet-1437	246	12	and	and	CCONJ
admet-1437	246	13	a	a	DET
admet-1437	246	14	fully	fully	ADV
admet-1437	246	15	amorphous	amorphous	ADJ
admet-1437	246	16	reference	reference	NOUN
admet-1437	246	17	in	in	ADP
admet-1437	246	18	the	the	DET
admet-1437	246	19	same	same	ADJ
admet-1437	246	20	medium	medium	NOUN
admet-1437	246	21	are	be	AUX
admet-1437	246	22	necessary	necessary	ADJ
admet-1437	246	23	.	.	PUNCT
admet-1437	247	1	unfortunately	unfortunately	ADV
admet-1437	247	2	,	,	PUNCT
admet-1437	247	3	suspension	suspension	NOUN
admet-1437	247	4	of	of	ADP
admet-1437	247	5	unmilled	unmilled	PROPN
admet-1437	247	6	material	material	PROPN
admet-1437	247	7	or	or	CCONJ
admet-1437	247	8	amorphous	amorphous	ADJ
admet-1437	247	9	drug	drug	NOUN
admet-1437	247	10	substance	substance	NOUN
admet-1437	247	11	could	could	AUX
admet-1437	247	12	not	not	PART
admet-1437	247	13	be	be	AUX
admet-1437	247	14	generated	generate	VERB
admet-1437	247	15	.	.	PUNCT
admet-1437	248	1	the	the	DET
admet-1437	248	2	unmilled	unmilled	PROPN
admet-1437	248	3	,	,	PUNCT
admet-1437	248	4	nominally	nominally	ADV
admet-1437	248	5	100	100	NUM
admet-1437	248	6	%	%	NOUN
admet-1437	248	7	crystalline	crystalline	NOUN
admet-1437	248	8	material	material	NOUN
admet-1437	248	9	does	do	AUX
admet-1437	248	10	not	not	PART
admet-1437	248	11	suspend	suspend	VERB
admet-1437	248	12	in	in	ADP
admet-1437	248	13	the	the	DET
admet-1437	248	14	aqueous	aqueous	ADJ
admet-1437	248	15	medium	medium	NOUN
admet-1437	248	16	,	,	PUNCT
admet-1437	248	17	while	while	SCONJ
admet-1437	248	18	the	the	DET
admet-1437	248	19	amorphous	amorphous	ADJ
admet-1437	248	20	material	material	NOUN
admet-1437	248	21	showed	show	VERB
admet-1437	248	22	rapid	rapid	ADJ
admet-1437	248	23	ostwald	ostwald	NOUN
admet-1437	248	24	ripening	ripening	NOUN
admet-1437	248	25	and	and	CCONJ
admet-1437	248	26	recrystallization	recrystallization	NOUN
admet-1437	248	27	.	.	PUNCT
admet-1437	249	1	consequently	consequently	ADV
admet-1437	249	2	,	,	PUNCT
admet-1437	249	3	no	no	DET
admet-1437	249	4	estimate	estimate	NOUN
admet-1437	249	5	for	for	SCONJ
admet-1437	249	6	the	the	DET
admet-1437	249	7	amorphous	amorphous	ADJ
admet-1437	249	8	content	content	NOUN
admet-1437	249	9	of	of	ADP
admet-1437	249	10	the	the	DET
admet-1437	249	11	suspensions	suspension	NOUN
admet-1437	249	12	can	can	AUX
admet-1437	249	13	be	be	AUX
admet-1437	249	14	given	give	VERB
admet-1437	249	15	.	.	PUNCT
admet-1437	250	1	however	however	ADV
admet-1437	250	2	,	,	PUNCT
admet-1437	250	3	using	use	VERB
admet-1437	250	4	the	the	DET
admet-1437	250	5	scherrer	scherrer	ADJ
admet-1437	250	6	equation	equation	NOUN
admet-1437	250	7	,	,	PUNCT
admet-1437	250	8	one	one	PRON
admet-1437	250	9	can	can	AUX
admet-1437	250	10	calculate	calculate	VERB
admet-1437	250	11	an	an	DET
admet-1437	250	12	average	average	ADJ
admet-1437	250	13	crystallite	crystallite	NOUN
admet-1437	250	14	size	size	NOUN
admet-1437	250	15	using	use	VERB
admet-1437	250	16	a	a	DET
admet-1437	250	17	crystalline	crystalline	ADJ
admet-1437	250	18	silicon	silicon	NOUN
admet-1437	250	19	standard	standard	NOUN
admet-1437	250	20	(	(	PUNCT
admet-1437	250	21	nist	nist	NOUN
admet-1437	250	22	®	®	NOUN
admet-1437	250	23	srm	srm	PROPN
admet-1437	250	24	®	®	NOUN
admet-1437	250	25	675	675	NUM
admet-1437	250	26	)	)	PUNCT
admet-1437	250	27	as	as	ADP
admet-1437	250	28	a	a	DET
admet-1437	250	29	reference	reference	NOUN
admet-1437	250	30	.	.	PUNCT
admet-1437	251	1	table	table	NOUN
admet-1437	251	2	4	4	NUM
admet-1437	251	3	shows	show	VERB
admet-1437	251	4	the	the	DET
admet-1437	251	5	peak	peak	NOUN
admet-1437	251	6	parameters	parameter	NOUN
admet-1437	251	7	obtained	obtain	VERB
admet-1437	251	8	from	from	ADP
admet-1437	251	9	the	the	DET
admet-1437	251	10	pattern	pattern	NOUN
admet-1437	251	11	,	,	PUNCT
admet-1437	251	12	the	the	DET
admet-1437	251	13	calculated	calculate	VERB
admet-1437	251	14	crystallite	crystallite	NOUN
admet-1437	251	15	size	size	NOUN
admet-1437	251	16	and	and	CCONJ
admet-1437	251	17	the	the	DET
admet-1437	251	18	known	know	VERB
admet-1437	251	19	median	median	ADJ
admet-1437	251	20	particle	particle	NOUN
admet-1437	251	21	size	size	NOUN
admet-1437	251	22	x50,3	x50,3	PROPN
admet-1437	251	23	.	.	PUNCT
admet-1437	252	1	the	the	DET
admet-1437	252	2	average	average	ADJ
admet-1437	252	3	peak	peak	NOUN
admet-1437	252	4	height	height	NOUN
admet-1437	252	5	is	be	AUX
admet-1437	252	6	steadily	steadily	ADV
admet-1437	252	7	diminishing	diminish	VERB
admet-1437	252	8	with	with	ADP
admet-1437	252	9	a	a	DET
admet-1437	252	10	smaller	small	ADJ
admet-1437	252	11	median	median	ADJ
admet-1437	252	12	particle	particle	NOUN
admet-1437	252	13	size	size	NOUN
admet-1437	252	14	.	.	PUNCT
admet-1437	253	1	the	the	DET
admet-1437	253	2	nanocrystals	nanocrystal	NOUN
admet-1437	253	3	of	of	ADP
admet-1437	253	4	experiments	experiment	NOUN
admet-1437	253	5	no	no	INTJ
admet-1437	253	6	.	.	NOUN
admet-1437	253	7	6	6	NUM
admet-1437	253	8	to	to	PART
admet-1437	253	9	8	8	NUM
admet-1437	253	10	have	have	VERB
admet-1437	253	11	a	a	DET
admet-1437	253	12	very	very	ADV
admet-1437	253	13	similar	similar	ADJ
admet-1437	253	14	,	,	PUNCT
admet-1437	253	15	if	if	SCONJ
admet-1437	253	16	not	not	PART
admet-1437	253	17	identical	identical	ADJ
admet-1437	253	18	,	,	PUNCT
admet-1437	253	19	average	average	ADJ
admet-1437	253	20	crystallite	crystallite	NOUN
admet-1437	253	21	size	size	NOUN
admet-1437	253	22	of	of	ADP
admet-1437	253	23	approximately	approximately	ADV
admet-1437	253	24	31	31	NUM
admet-1437	253	25	nm	nm	NOUN
admet-1437	253	26	.	.	PUNCT
admet-1437	254	1	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	X
admet-1437	254	2	bonhoeffer	bonhoeffer	PROPN
admet-1437	254	3	et	et	PROPN
admet-1437	254	4	al	al	PROPN
admet-1437	254	5	.	.	PROPN
admet-1437	254	6	admet	admet	PROPN
admet-1437	254	7	&	&	CCONJ
admet-1437	254	8	dmpk	dmpk	PROPN
admet-1437	254	9	10(4	10(4	NUM
admet-1437	254	10	)	)	PUNCT
admet-1437	254	11	(	(	PUNCT
admet-1437	254	12	2022	2022	NUM
admet-1437	254	13	)	)	PUNCT
admet-1437	254	14	253	253	NUM
admet-1437	254	15	-	-	SYM
admet-1437	254	16	287	287	NUM
admet-1437	254	17	266	266	NUM
admet-1437	254	18	table	table	NOUN
admet-1437	254	19	4	4	NUM
admet-1437	254	20	.	.	PUNCT
admet-1437	254	21	nanocrystal	nanocrystal	ADJ
admet-1437	254	22	particle	particle	NOUN
admet-1437	254	23	size	size	NOUN
admet-1437	254	24	x50,3	x50,3	PROPN
admet-1437	255	1	for	for	ADP
admet-1437	255	2	experiments	experiment	NOUN
admet-1437	255	3	no.1	no.1	VERB
admet-1437	255	4	and	and	CCONJ
admet-1437	255	5	6	6	NUM
admet-1437	255	6	to	to	PART
admet-1437	255	7	8	8	NUM
admet-1437	255	8	and	and	CCONJ
admet-1437	255	9	calculated	calculate	VERB
admet-1437	255	10	crystallite	crystallite	NOUN
admet-1437	255	11	size	size	NOUN
admet-1437	255	12	from	from	ADP
admet-1437	255	13	transmission	transmission	NOUN
admet-1437	255	14	xrpd	xrpd	PROPN
admet-1437	255	15	peak	peak	NOUN
admet-1437	255	16	data	datum	NOUN
admet-1437	255	17	at	at	ADP
admet-1437	255	18	13.7	13.7	NUM
admet-1437	255	19	°	°	NUM
admet-1437	255	20	2θ	2θ	NUM
admet-1437	255	21	.	.	PUNCT
admet-1437	256	1	experiment	experiment	NOUN
admet-1437	256	2	no	no	PROPN
admet-1437	256	3	.	.	PUNCT
admet-1437	256	4	particle	particle	NOUN
admet-1437	256	5	size	size	NOUN
admet-1437	256	6	x50,3	x50,3	PROPN
admet-1437	256	7	/	/	SYM
admet-1437	256	8	nm	nm	PROPN
admet-1437	256	9	intensity	intensity	NOUN
admet-1437	256	10	/	/	SYM
admet-1437	256	11	cps	cps	PROPN
admet-1437	256	12	crystallite	crystallite	NOUN
admet-1437	256	13	size	size	NOUN
admet-1437	256	14	/	/	SYM
admet-1437	256	15	å	å	PROPN
admet-1437	256	16	1	1	NUM
admet-1437	256	17	2443	2443	NUM
admet-1437	256	18	2114	2114	NUM
admet-1437	256	19	1050	1050	NUM
admet-1437	256	20	6	6	NUM
admet-1437	256	21	93	93	NUM
admet-1437	256	22	618	618	NUM
admet-1437	256	23	320	320	NUM
admet-1437	256	24	7	7	NUM
admet-1437	256	25	90	90	NUM
admet-1437	256	26	563	563	NUM
admet-1437	256	27	285	285	NUM
admet-1437	256	28	8	8	NUM
admet-1437	256	29	79	79	NUM
admet-1437	256	30	516	516	NUM
admet-1437	256	31	325	325	NUM
admet-1437	256	32	plotting	plot	VERB
admet-1437	256	33	the	the	DET
admet-1437	256	34	peak	peak	NOUN
admet-1437	256	35	height	height	NOUN
admet-1437	256	36	at	at	ADP
admet-1437	256	37	13.7	13.7	NUM
admet-1437	256	38	°	°	NOUN
admet-1437	256	39	against	against	ADP
admet-1437	256	40	the	the	DET
admet-1437	256	41	measured	measure	VERB
admet-1437	256	42	particle	particle	NOUN
admet-1437	256	43	size	size	NOUN
admet-1437	256	44	in	in	ADP
admet-1437	256	45	a	a	DET
admet-1437	256	46	semi	semi	ADJ
admet-1437	256	47	-	-	ADJ
admet-1437	256	48	logarithmic	logarithmic	ADJ
admet-1437	256	49	plot	plot	NOUN
admet-1437	256	50	allows	allow	VERB
admet-1437	256	51	fitting	fit	VERB
admet-1437	256	52	a	a	DET
admet-1437	256	53	linear	linear	ADJ
admet-1437	256	54	trendline	trendline	NOUN
admet-1437	256	55	through	through	ADP
admet-1437	256	56	the	the	DET
admet-1437	256	57	data	datum	NOUN
admet-1437	256	58	,	,	PUNCT
admet-1437	256	59	whose	whose	DET
admet-1437	256	60	root	root	NOUN
admet-1437	256	61	predicts	predict	VERB
admet-1437	256	62	a	a	DET
admet-1437	256	63	likely	likely	ADJ
admet-1437	256	64	particle	particle	NOUN
admet-1437	256	65	size	size	NOUN
admet-1437	256	66	at	at	ADP
admet-1437	256	67	which	which	PRON
admet-1437	256	68	the	the	DET
admet-1437	256	69	peaks	peak	NOUN
admet-1437	256	70	’	'	PUNCT
admet-1437	256	71	diffraction	diffraction	NOUN
admet-1437	256	72	signal	signal	NOUN
admet-1437	256	73	would	would	AUX
admet-1437	256	74	be	be	AUX
admet-1437	256	75	merging	merge	VERB
admet-1437	256	76	with	with	ADP
admet-1437	256	77	the	the	DET
admet-1437	256	78	amorphous	amorphous	ADJ
admet-1437	256	79	background	background	NOUN
admet-1437	256	80	.	.	PUNCT
admet-1437	257	1	the	the	DET
admet-1437	257	2	extrapolation	extrapolation	NOUN
admet-1437	257	3	estimates	estimate	VERB
admet-1437	257	4	that	that	SCONJ
admet-1437	257	5	below	below	ADP
admet-1437	257	6	a	a	DET
admet-1437	257	7	particle	particle	NOUN
admet-1437	257	8	size	size	NOUN
admet-1437	257	9	of	of	ADP
admet-1437	257	10	approximately	approximately	ADV
admet-1437	257	11	21	21	NUM
admet-1437	257	12	nm	nm	NOUN
admet-1437	257	13	,	,	PUNCT
admet-1437	257	14	the	the	DET
admet-1437	257	15	drug	drug	NOUN
admet-1437	257	16	substance	substance	NOUN
admet-1437	257	17	would	would	AUX
admet-1437	257	18	become	become	VERB
admet-1437	257	19	x	x	ADJ
admet-1437	257	20	-	-	NOUN
admet-1437	257	21	ray	ray	NOUN
admet-1437	257	22	amorphous	amorphous	ADJ
admet-1437	257	23	,	,	PUNCT
admet-1437	257	24	with	with	ADP
admet-1437	257	25	the	the	DET
admet-1437	257	26	exact	exact	ADJ
admet-1437	257	27	nature	nature	NOUN
admet-1437	257	28	of	of	ADP
admet-1437	257	29	the	the	DET
admet-1437	257	30	particles	particle	NOUN
admet-1437	257	31	,	,	PUNCT
admet-1437	257	32	i.e.	i.e.	X
admet-1437	257	33	,	,	PUNCT
admet-1437	257	34	crystalline	crystalline	ADJ
admet-1437	257	35	or	or	CCONJ
admet-1437	257	36	amorphous	amorphous	ADJ
admet-1437	257	37	,	,	PUNCT
admet-1437	257	38	being	be	AUX
admet-1437	257	39	undeterminable	undeterminable	ADJ
admet-1437	257	40	.	.	PUNCT
admet-1437	258	1	it	it	PRON
admet-1437	258	2	should	should	AUX
admet-1437	258	3	be	be	AUX
admet-1437	258	4	noted	note	VERB
admet-1437	258	5	that	that	SCONJ
admet-1437	258	6	a	a	DET
admet-1437	258	7	crystal	crystal	NOUN
admet-1437	258	8	of	of	ADP
admet-1437	258	9	21	21	NUM
admet-1437	258	10	nm	nm	NOUN
admet-1437	258	11	would	would	AUX
admet-1437	258	12	still	still	ADV
admet-1437	258	13	contain	contain	VERB
admet-1437	258	14	about	about	ADP
admet-1437	258	15	7000	7000	NUM
admet-1437	258	16	unit	unit	NOUN
admet-1437	258	17	cells	cell	NOUN
admet-1437	258	18	.	.	PUNCT
admet-1437	259	1	however	however	ADV
admet-1437	259	2	,	,	PUNCT
admet-1437	259	3	about	about	ADV
admet-1437	259	4	28	28	NUM
admet-1437	259	5	%	%	NOUN
admet-1437	259	6	,	,	PUNCT
admet-1437	259	7	i.e.	i.e.	X
admet-1437	259	8	,	,	PUNCT
admet-1437	259	9	2000	2000	NUM
admet-1437	259	10	of	of	ADP
admet-1437	259	11	those	those	PRON
admet-1437	259	12	would	would	AUX
admet-1437	259	13	already	already	ADV
admet-1437	259	14	constitute	constitute	VERB
admet-1437	259	15	a	a	DET
admet-1437	259	16	single	single	ADJ
admet-1437	259	17	surface	surface	NOUN
admet-1437	259	18	layer	layer	NOUN
admet-1437	259	19	and	and	CCONJ
admet-1437	259	20	three	three	NUM
admet-1437	259	21	layers	layer	NOUN
admet-1437	259	22	would	would	AUX
admet-1437	259	23	amount	amount	VERB
admet-1437	259	24	to	to	ADP
admet-1437	259	25	68	68	NUM
admet-1437	259	26	%	%	NOUN
admet-1437	259	27	,	,	PUNCT
admet-1437	259	28	notwithstanding	notwithstanding	ADP
admet-1437	259	29	internal	internal	ADJ
admet-1437	259	30	dislocations	dislocation	NOUN
admet-1437	259	31	and	and	CCONJ
admet-1437	259	32	grain	grain	NOUN
admet-1437	259	33	boundaries	boundary	NOUN
admet-1437	259	34	that	that	PRON
admet-1437	259	35	would	would	AUX
admet-1437	259	36	further	far	ADV
admet-1437	259	37	reduce	reduce	VERB
admet-1437	259	38	any	any	DET
admet-1437	259	39	diffraction	diffraction	NOUN
admet-1437	259	40	signal	signal	NOUN
admet-1437	259	41	.	.	PUNCT
admet-1437	260	1	therefore	therefore	ADV
admet-1437	260	2	,	,	PUNCT
admet-1437	260	3	a	a	DET
admet-1437	260	4	more	more	ADV
admet-1437	260	5	appropriate	appropriate	ADJ
admet-1437	260	6	limit	limit	NOUN
admet-1437	260	7	of	of	ADP
admet-1437	260	8	detection	detection	NOUN
admet-1437	260	9	of	of	ADP
admet-1437	260	10	crystallinity	crystallinity	NOUN
admet-1437	260	11	by	by	ADP
admet-1437	260	12	transmission	transmission	NOUN
admet-1437	260	13	xrpd	xrpd	NOUN
admet-1437	260	14	should	should	AUX
admet-1437	260	15	be	be	AUX
admet-1437	260	16	above	above	ADP
admet-1437	260	17	a	a	DET
admet-1437	260	18	particle	particle	NOUN
admet-1437	260	19	size	size	NOUN
admet-1437	260	20	of	of	ADP
admet-1437	260	21	21	21	NUM
admet-1437	260	22	nm	nm	NOUN
admet-1437	260	23	.	.	PUNCT
admet-1437	261	1	it	it	PRON
admet-1437	261	2	should	should	AUX
admet-1437	261	3	be	be	AUX
admet-1437	261	4	kept	keep	VERB
admet-1437	261	5	in	in	ADP
admet-1437	261	6	mind	mind	NOUN
admet-1437	261	7	that	that	SCONJ
admet-1437	261	8	the	the	DET
admet-1437	261	9	samples	sample	NOUN
admet-1437	261	10	actually	actually	ADV
admet-1437	261	11	have	have	VERB
admet-1437	261	12	a	a	DET
admet-1437	261	13	particle	particle	NOUN
admet-1437	261	14	size	size	NOUN
admet-1437	261	15	distribution	distribution	NOUN
admet-1437	261	16	and	and	CCONJ
admet-1437	261	17	that	that	SCONJ
admet-1437	261	18	the	the	DET
admet-1437	261	19	xrpd	xrpd	PROPN
admet-1437	261	20	signal	signal	NOUN
admet-1437	261	21	is	be	AUX
admet-1437	261	22	a	a	DET
admet-1437	261	23	superposition	superposition	NOUN
admet-1437	261	24	of	of	ADP
admet-1437	261	25	the	the	DET
admet-1437	261	26	individual	individual	ADJ
admet-1437	261	27	contributions	contribution	NOUN
admet-1437	261	28	of	of	ADP
admet-1437	261	29	each	each	DET
admet-1437	261	30	particle	particle	NOUN
admet-1437	261	31	size	size	NOUN
admet-1437	261	32	in	in	ADP
admet-1437	261	33	the	the	DET
admet-1437	261	34	sample	sample	NOUN
admet-1437	261	35	.	.	PUNCT
admet-1437	262	1	indeed	indeed	ADV
admet-1437	262	2	,	,	PUNCT
admet-1437	262	3	an	an	DET
admet-1437	262	4	sem	sem	NOUN
admet-1437	262	5	of	of	ADP
admet-1437	262	6	a	a	DET
admet-1437	262	7	sample	sample	NOUN
admet-1437	262	8	with	with	ADP
admet-1437	262	9	a	a	DET
admet-1437	262	10	median	median	ADJ
admet-1437	262	11	particle	particle	NOUN
admet-1437	262	12	size	size	NOUN
admet-1437	262	13	x50,3	x50,3	PUNCT
admet-1437	263	1	=	=	SYM
admet-1437	263	2	79	79	NUM
admet-1437	263	3	nm	nm	NOUN
admet-1437	263	4	shows	show	VERB
admet-1437	263	5	that	that	SCONJ
admet-1437	263	6	the	the	DET
admet-1437	263	7	sample	sample	NOUN
admet-1437	263	8	exhibits	exhibit	VERB
admet-1437	263	9	particles	particle	NOUN
admet-1437	263	10	that	that	PRON
admet-1437	263	11	represent	represent	VERB
admet-1437	263	12	particle	particle	NOUN
admet-1437	263	13	sizes	size	NOUN
admet-1437	263	14	according	accord	VERB
admet-1437	263	15	to	to	ADP
admet-1437	263	16	the	the	DET
admet-1437	263	17	determined	determined	ADJ
admet-1437	263	18	particle	particle	NOUN
admet-1437	263	19	size	size	NOUN
admet-1437	263	20	distribution	distribution	NOUN
admet-1437	263	21	,	,	PUNCT
admet-1437	263	22	see	see	VERB
admet-1437	263	23	experiment	experiment	NOUN
admet-1437	263	24	no	no	NOUN
admet-1437	263	25	.	.	NOUN
admet-1437	263	26	8	8	NUM
admet-1437	263	27	in	in	ADP
admet-1437	263	28	table	table	NOUN
admet-1437	263	29	2	2	NUM
admet-1437	263	30	and	and	CCONJ
admet-1437	263	31	sem	sem	NOUN
admet-1437	263	32	in	in	ADP
admet-1437	263	33	figure	figure	NOUN
admet-1437	263	34	2(h	2(h	NUM
admet-1437	263	35	)	)	PUNCT
admet-1437	263	36	.	.	PUNCT
admet-1437	264	1	however	however	ADV
admet-1437	264	2	,	,	PUNCT
admet-1437	264	3	nanocrystal	nanocrystal	ADJ
admet-1437	264	4	particles	particle	NOUN
admet-1437	264	5	in	in	ADP
admet-1437	264	6	the	the	DET
admet-1437	264	7	vicinity	vicinity	NOUN
admet-1437	264	8	of	of	ADP
admet-1437	264	9	30	30	NUM
admet-1437	264	10	nm	nm	NOUN
admet-1437	264	11	and	and	CCONJ
admet-1437	264	12	even	even	ADV
admet-1437	264	13	around	around	ADV
admet-1437	264	14	20	20	NUM
admet-1437	264	15	nm	nm	NOUN
admet-1437	264	16	can	can	AUX
admet-1437	264	17	be	be	AUX
admet-1437	264	18	found	find	VERB
admet-1437	264	19	in	in	ADP
admet-1437	264	20	the	the	DET
admet-1437	264	21	high	high	ADJ
admet-1437	264	22	magnification	magnification	NOUN
admet-1437	264	23	sem	sem	NOUN
admet-1437	264	24	in	in	ADP
admet-1437	264	25	figure	figure	NOUN
admet-1437	264	26	2(h	2(h	NUM
admet-1437	264	27	)	)	PUNCT
admet-1437	264	28	.	.	PUNCT
admet-1437	265	1	the	the	DET
admet-1437	265	2	liquid	liquid	ADJ
admet-1437	265	3	nature	nature	NOUN
admet-1437	265	4	of	of	ADP
admet-1437	265	5	the	the	DET
admet-1437	265	6	suspensions	suspension	NOUN
admet-1437	265	7	makes	make	VERB
admet-1437	265	8	handling	handling	NOUN
admet-1437	265	9	and	and	CCONJ
admet-1437	265	10	measurement	measurement	NOUN
admet-1437	265	11	awkward	awkward	ADJ
admet-1437	265	12	for	for	ADP
admet-1437	265	13	xrpd	xrpd	ADJ
admet-1437	265	14	investigations	investigation	NOUN
admet-1437	265	15	in	in	ADP
admet-1437	265	16	reflection	reflection	NOUN
admet-1437	265	17	mode	mode	NOUN
admet-1437	265	18	.	.	PUNCT
admet-1437	266	1	it	it	PRON
admet-1437	266	2	is	be	AUX
admet-1437	266	3	preferable	preferable	ADJ
admet-1437	266	4	to	to	PART
admet-1437	266	5	handle	handle	VERB
admet-1437	266	6	the	the	DET
admet-1437	266	7	samples	sample	NOUN
admet-1437	266	8	as	as	ADP
admet-1437	266	9	dry	dry	ADJ
admet-1437	266	10	powders	powder	NOUN
admet-1437	266	11	.	.	PUNCT
admet-1437	267	1	to	to	PART
admet-1437	267	2	obtain	obtain	VERB
admet-1437	267	3	dry	dry	ADJ
admet-1437	267	4	powder	powder	NOUN
admet-1437	267	5	,	,	PUNCT
admet-1437	267	6	one	one	NUM
admet-1437	267	7	milliliter	milliliter	NOUN
admet-1437	267	8	of	of	ADP
admet-1437	267	9	selected	select	VERB
admet-1437	267	10	suspensions	suspension	NOUN
admet-1437	267	11	was	be	AUX
admet-1437	267	12	dried	dry	VERB
admet-1437	267	13	at	at	ADP
admet-1437	267	14	50	50	NUM
admet-1437	267	15	°	°	NOUN
admet-1437	267	16	c	c	NOUN
admet-1437	267	17	in	in	ADP
admet-1437	267	18	an	an	DET
admet-1437	267	19	oven	oven	NOUN
admet-1437	267	20	for	for	ADP
admet-1437	267	21	a	a	DET
admet-1437	267	22	week	week	NOUN
admet-1437	267	23	.	.	PUNCT
admet-1437	268	1	the	the	DET
admet-1437	268	2	solid	solid	ADJ
admet-1437	268	3	residue	residue	NOUN
admet-1437	268	4	obtained	obtain	VERB
admet-1437	268	5	after	after	ADP
admet-1437	268	6	drying	dry	VERB
admet-1437	268	7	was	be	AUX
admet-1437	268	8	ground	grind	VERB
admet-1437	268	9	into	into	ADP
admet-1437	268	10	a	a	DET
admet-1437	268	11	fine	fine	ADJ
admet-1437	268	12	powder	powder	NOUN
admet-1437	268	13	in	in	ADP
admet-1437	268	14	an	an	DET
admet-1437	268	15	agate	agate	ADJ
admet-1437	268	16	mortar	mortar	NOUN
admet-1437	268	17	.	.	PUNCT
admet-1437	269	1	in	in	ADP
admet-1437	269	2	addition	addition	NOUN
admet-1437	269	3	,	,	PUNCT
admet-1437	269	4	the	the	DET
admet-1437	269	5	reflection	reflection	NOUN
admet-1437	269	6	measurements	measurement	NOUN
admet-1437	269	7	allow	allow	VERB
admet-1437	269	8	the	the	DET
admet-1437	269	9	generation	generation	NOUN
admet-1437	269	10	of	of	ADP
admet-1437	269	11	a	a	DET
admet-1437	269	12	calibration	calibration	NOUN
admet-1437	269	13	line	line	NOUN
admet-1437	269	14	with	with	ADP
admet-1437	269	15	respect	respect	NOUN
admet-1437	269	16	to	to	ADP
admet-1437	269	17	the	the	DET
admet-1437	269	18	amorphous	amorphous	ADJ
admet-1437	269	19	content	content	NOUN
admet-1437	269	20	by	by	ADP
admet-1437	269	21	using	use	VERB
admet-1437	269	22	unmilled	unmilled	PROPN
admet-1437	269	23	crystalline	crystalline	PROPN
admet-1437	269	24	material	material	NOUN
admet-1437	269	25	and	and	CCONJ
admet-1437	269	26	amorphous	amorphous	ADJ
admet-1437	269	27	drug	drug	NOUN
admet-1437	269	28	substance	substance	NOUN
admet-1437	269	29	as	as	ADP
admet-1437	269	30	100	100	NUM
admet-1437	269	31	%	%	NOUN
admet-1437	269	32	and	and	CCONJ
admet-1437	269	33	0	0	NUM
admet-1437	269	34	%	%	NOUN
admet-1437	269	35	crystalline	crystalline	NOUN
admet-1437	269	36	reference	reference	NOUN
admet-1437	269	37	,	,	PUNCT
admet-1437	269	38	respectively	respectively	ADV
admet-1437	269	39	.	.	PUNCT
admet-1437	270	1	further	far	ADV
admet-1437	270	2	,	,	PUNCT
admet-1437	270	3	physical	physical	ADJ
admet-1437	270	4	mixtures	mixture	NOUN
admet-1437	270	5	of	of	ADP
admet-1437	270	6	these	these	PRON
admet-1437	270	7	allow	allow	VERB
admet-1437	270	8	the	the	DET
admet-1437	270	9	preparation	preparation	NOUN
admet-1437	270	10	of	of	ADP
admet-1437	270	11	calibration	calibration	NOUN
admet-1437	270	12	mixtures	mixture	NOUN
admet-1437	270	13	with	with	ADP
admet-1437	270	14	known	know	VERB
admet-1437	270	15	amorphous	amorphous	ADJ
admet-1437	270	16	content	content	NOUN
admet-1437	270	17	.	.	PUNCT
admet-1437	271	1	the	the	DET
admet-1437	271	2	suspensions	suspension	NOUN
admet-1437	271	3	also	also	ADV
admet-1437	271	4	contain	contain	VERB
admet-1437	271	5	4	4	NUM
admet-1437	271	6	%	%	NOUN
admet-1437	271	7	w	w	NOUN
admet-1437	271	8	of	of	ADP
admet-1437	271	9	stabilizer	stabilizer	NOUN
admet-1437	271	10	,	,	PUNCT
admet-1437	271	11	which	which	PRON
admet-1437	271	12	relates	relate	VERB
admet-1437	271	13	to	to	ADP
admet-1437	271	14	13.79	13.79	NUM
admet-1437	271	15	%	%	NOUN
admet-1437	271	16	w	w	NOUN
admet-1437	271	17	in	in	ADP
admet-1437	271	18	the	the	DET
admet-1437	271	19	dried	dry	VERB
admet-1437	271	20	samples	sample	NOUN
admet-1437	271	21	.	.	PUNCT
admet-1437	272	1	therefore	therefore	ADV
admet-1437	272	2	,	,	PUNCT
admet-1437	272	3	the	the	DET
admet-1437	272	4	patterns	pattern	NOUN
admet-1437	272	5	obtained	obtain	VERB
admet-1437	272	6	were	be	AUX
admet-1437	272	7	corrected	correct	VERB
admet-1437	272	8	for	for	ADP
admet-1437	272	9	their	their	PRON
admet-1437	272	10	stabilizer	stabilizer	NOUN
admet-1437	272	11	contribution	contribution	NOUN
admet-1437	272	12	.	.	PUNCT
admet-1437	273	1	each	each	DET
admet-1437	273	2	sample	sample	NOUN
admet-1437	273	3	was	be	AUX
admet-1437	273	4	measured	measure	VERB
admet-1437	273	5	in	in	ADP
admet-1437	273	6	triplicate	triplicate	NOUN
admet-1437	273	7	and	and	CCONJ
admet-1437	273	8	an	an	DET
admet-1437	273	9	average	average	NOUN
admet-1437	273	10	of	of	ADP
admet-1437	273	11	the	the	DET
admet-1437	273	12	three	three	NUM
admet-1437	273	13	individual	individual	ADJ
admet-1437	273	14	datasets	dataset	NOUN
admet-1437	273	15	was	be	AUX
admet-1437	273	16	used	use	VERB
admet-1437	273	17	to	to	PART
admet-1437	273	18	minimize	minimize	VERB
admet-1437	273	19	intensity	intensity	NOUN
admet-1437	273	20	errors	error	NOUN
admet-1437	273	21	.	.	PUNCT
admet-1437	274	1	further	far	ADV
admet-1437	274	2	,	,	PUNCT
admet-1437	274	3	each	each	DET
admet-1437	274	4	sample	sample	NOUN
admet-1437	274	5	was	be	AUX
admet-1437	274	6	weighed	weigh	VERB
admet-1437	274	7	to	to	ADP
admet-1437	274	8	10.0	10.0	NUM
admet-1437	274	9	±	±	NUM
admet-1437	274	10	0.050	0.050	NUM
admet-1437	274	11	mg	mg	NOUN
admet-1437	274	12	to	to	PART
admet-1437	274	13	minimize	minimize	VERB
admet-1437	274	14	intensity	intensity	NOUN
admet-1437	274	15	variations	variation	NOUN
admet-1437	274	16	due	due	ADP
admet-1437	274	17	to	to	ADP
admet-1437	274	18	differences	difference	NOUN
admet-1437	274	19	in	in	ADP
admet-1437	274	20	mass	mass	ADJ
admet-1437	274	21	absorption	absorption	NOUN
admet-1437	274	22	between	between	ADP
admet-1437	274	23	samples	sample	NOUN
admet-1437	274	24	.	.	PUNCT
admet-1437	275	1	the	the	DET
admet-1437	275	2	stabilizer	stabilizer	NOUN
admet-1437	275	3	contribution	contribution	NOUN
admet-1437	275	4	was	be	AUX
admet-1437	275	5	subtracted	subtract	VERB
admet-1437	275	6	from	from	ADP
admet-1437	275	7	the	the	DET
admet-1437	275	8	suspension	suspension	NOUN
admet-1437	275	9	raw	raw	ADJ
admet-1437	275	10	data	datum	NOUN
admet-1437	275	11	,	,	PUNCT
admet-1437	275	12	and	and	CCONJ
admet-1437	275	13	the	the	DET
admet-1437	275	14	pure	pure	ADJ
admet-1437	275	15	solid	solid	ADJ
admet-1437	275	16	samples	sample	NOUN
admet-1437	275	17	,	,	PUNCT
admet-1437	275	18	i.e.	i.e.	X
admet-1437	275	19	,	,	PUNCT
admet-1437	275	20	unmilled	unmilled	PROPN
admet-1437	275	21	crystalline	crystalline	PROPN
admet-1437	275	22	,	,	PUNCT
admet-1437	275	23	amorphous	amorphous	ADJ
admet-1437	275	24	and	and	CCONJ
admet-1437	275	25	micron	micron	NOUN
admet-1437	275	26	-	-	PUNCT
admet-1437	275	27	sized	sized	ADJ
admet-1437	275	28	samples	sample	NOUN
admet-1437	275	29	,	,	PUNCT
admet-1437	275	30	were	be	AUX
admet-1437	275	31	weighted	weight	VERB
admet-1437	275	32	accordingly	accordingly	ADV
admet-1437	275	33	.	.	PUNCT
admet-1437	276	1	the	the	DET
admet-1437	276	2	pattern	pattern	NOUN
admet-1437	276	3	of	of	ADP
admet-1437	276	4	the	the	DET
admet-1437	276	5	si	si	NOUN
admet-1437	276	6	-	-	PUNCT
admet-1437	276	7	holder	holder	NOUN
admet-1437	276	8	was	be	AUX
admet-1437	276	9	subtracted	subtract	VERB
admet-1437	276	10	subsequently	subsequently	ADV
admet-1437	276	11	,	,	PUNCT
admet-1437	276	12	and	and	CCONJ
admet-1437	276	13	the	the	DET
admet-1437	276	14	resulting	result	VERB
admet-1437	276	15	patterns	pattern	NOUN
admet-1437	276	16	were	be	AUX
admet-1437	276	17	smoothed	smooth	VERB
admet-1437	276	18	with	with	ADP
admet-1437	276	19	a	a	DET
admet-1437	276	20	9	9	NUM
admet-1437	276	21	-	-	PUNCT
admet-1437	276	22	point	point	NOUN
admet-1437	276	23	straight	straight	ADJ
admet-1437	276	24	line	line	NOUN
admet-1437	276	25	savitzky	savitzky	NOUN
admet-1437	276	26	-	-	PUNCT
admet-1437	276	27	golay	golay	NOUN
admet-1437	276	28	window	window	NOUN
admet-1437	276	29	,	,	PUNCT
admet-1437	276	30	resulting	result	VERB
admet-1437	276	31	in	in	ADP
admet-1437	276	32	a	a	DET
admet-1437	276	33	less	less	ADV
admet-1437	276	34	noisy	noisy	ADJ
admet-1437	276	35	pattern	pattern	NOUN
admet-1437	276	36	overall	overall	ADV
admet-1437	276	37	,	,	PUNCT
admet-1437	276	38	see	see	VERB
admet-1437	276	39	figure	figure	NOUN
admet-1437	276	40	5	5	NUM
admet-1437	276	41	.	.	PUNCT
admet-1437	277	1	the	the	DET
admet-1437	277	2	physical	physical	ADJ
admet-1437	277	3	mixtures	mixture	NOUN
admet-1437	277	4	together	together	ADV
admet-1437	277	5	with	with	ADP
admet-1437	277	6	the	the	DET
admet-1437	277	7	crystalline	crystalline	ADJ
admet-1437	277	8	and	and	CCONJ
admet-1437	277	9	amorphous	amorphous	ADJ
admet-1437	277	10	material	material	NOUN
admet-1437	277	11	,	,	PUNCT
admet-1437	277	12	allowed	allow	VERB
admet-1437	277	13	the	the	DET
admet-1437	277	14	generation	generation	NOUN
admet-1437	277	15	of	of	ADP
admet-1437	277	16	a	a	DET
admet-1437	277	17	calibration	calibration	NOUN
admet-1437	277	18	line	line	NOUN
admet-1437	277	19	by	by	ADP
admet-1437	277	20	plotting	plot	VERB
admet-1437	277	21	the	the	DET
admet-1437	277	22	crystalline	crystalline	ADJ
admet-1437	277	23	content	content	NOUN
admet-1437	277	24	against	against	ADP
admet-1437	277	25	the	the	DET
admet-1437	277	26	baseline	baseline	NOUN
admet-1437	277	27	intensity	intensity	NOUN
admet-1437	277	28	.	.	PUNCT
admet-1437	278	1	the	the	DET
admet-1437	278	2	area	area	NOUN
admet-1437	278	3	around	around	ADP
admet-1437	278	4	17	17	NUM
admet-1437	278	5	°	°	NOUN
admet-1437	278	6	2θ	2θ	NUM
admet-1437	278	7	is	be	AUX
admet-1437	278	8	considered	consider	VERB
admet-1437	278	9	suitable	suitable	ADJ
admet-1437	278	10	for	for	ADP
admet-1437	278	11	analysis	analysis	NOUN
admet-1437	278	12	.	.	PUNCT
admet-1437	279	1	a	a	DET
admet-1437	279	2	calibration	calibration	NOUN
admet-1437	279	3	line	line	NOUN
admet-1437	279	4	at	at	ADP
admet-1437	279	5	16.994	16.994	NUM
admet-1437	279	6	°	°	NOUN
admet-1437	279	7	2θ	2θ	NUM
admet-1437	279	8	was	be	AUX
admet-1437	279	9	generated	generate	VERB
admet-1437	279	10	,	,	PUNCT
admet-1437	279	11	including	include	VERB
admet-1437	279	12	regression	regression	NOUN
admet-1437	279	13	and	and	CCONJ
admet-1437	279	14	error	error	NOUN
admet-1437	279	15	analysis	analysis	NOUN
admet-1437	279	16	.	.	PUNCT
admet-1437	280	1	the	the	DET
admet-1437	280	2	intensity	intensity	NOUN
admet-1437	280	3	error	error	NOUN
admet-1437	280	4	was	be	AUX
admet-1437	280	5	calculated	calculate	VERB
admet-1437	280	6	as	as	ADP
admet-1437	280	7	the	the	DET
admet-1437	280	8	standard	standard	ADJ
admet-1437	280	9	deviation	deviation	NOUN
admet-1437	280	10	of	of	ADP
admet-1437	280	11	three	three	NUM
admet-1437	280	12	measurements	measurement	NOUN
admet-1437	280	13	for	for	ADP
admet-1437	280	14	the	the	DET
admet-1437	280	15	four	four	NUM
admet-1437	280	16	calibration	calibration	NOUN
admet-1437	280	17	mixtures	mixture	NOUN
admet-1437	280	18	,	,	PUNCT
admet-1437	280	19	see	see	VERB
admet-1437	280	20	figure	figure	NOUN
admet-1437	280	21	6	6	NUM
admet-1437	280	22	.	.	PUNCT
admet-1437	281	1	the	the	DET
admet-1437	281	2	regression	regression	NOUN
admet-1437	281	3	line	line	NOUN
admet-1437	281	4	and	and	CCONJ
admet-1437	281	5	the	the	DET
admet-1437	281	6	95	95	NUM
admet-1437	281	7	%	%	NOUN
admet-1437	281	8	-confidence	-confidence	NOUN
admet-1437	281	9	limits	limit	NOUN
admet-1437	281	10	were	be	AUX
admet-1437	281	11	calculated	calculate	VERB
admet-1437	281	12	using	use	VERB
admet-1437	281	13	microsoft	microsoft	PROPN
admet-1437	281	14	excel	excel	PROPN
admet-1437	281	15	2016	2016	NUM
admet-1437	281	16	.	.	PUNCT
admet-1437	282	1	an	an	DET
admet-1437	282	2	excellent	excellent	ADJ
admet-1437	282	3	fit	fit	ADJ
admet-1437	282	4	and	and	CCONJ
admet-1437	282	5	high	high	ADJ
admet-1437	282	6	regression	regression	NOUN
admet-1437	282	7	coefficient	coefficient	NOUN
admet-1437	282	8	give	give	VERB
admet-1437	282	9	credence	credence	NOUN
admet-1437	282	10	to	to	ADP
admet-1437	282	11	the	the	DET
admet-1437	282	12	assumption	assumption	NOUN
admet-1437	282	13	that	that	SCONJ
admet-1437	282	14	admet	admet	PROPN
admet-1437	282	15	&	&	CCONJ
admet-1437	282	16	dmpk	dmpk	PROPN
admet-1437	282	17	10(4	10(4	NUM
admet-1437	282	18	)	)	PUNCT
admet-1437	282	19	(	(	PUNCT
admet-1437	282	20	2022	2022	NUM
admet-1437	282	21	)	)	PUNCT
admet-1437	282	22	253	253	NUM
admet-1437	282	23	-	-	SYM
admet-1437	282	24	287	287	NUM
admet-1437	282	25	modeling	modeling	NOUN
admet-1437	282	26	of	of	ADP
admet-1437	282	27	drug	drug	NOUN
admet-1437	282	28	nanocrystals	nanocrystal	NOUN
admet-1437	282	29	dissolution	dissolution	NOUN
admet-1437	282	30	doi	doi	PROPN
admet-1437	282	31	:	:	PUNCT
admet-1437	282	32	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	282	33	267	267	NUM
admet-1437	282	34	the	the	DET
admet-1437	282	35	baseline	baseline	NOUN
admet-1437	282	36	intensity	intensity	NOUN
admet-1437	282	37	is	be	AUX
admet-1437	282	38	indeed	indeed	ADV
admet-1437	282	39	linearly	linearly	ADV
admet-1437	282	40	correlated	correlate	VERB
admet-1437	282	41	to	to	ADP
admet-1437	282	42	the	the	DET
admet-1437	282	43	crystalline	crystalline	ADJ
admet-1437	282	44	mass	mass	NOUN
admet-1437	282	45	fraction	fraction	NOUN
admet-1437	282	46	.	.	PUNCT
admet-1437	283	1	figure	figure	NOUN
admet-1437	283	2	5	5	NUM
admet-1437	283	3	.	.	PUNCT
admet-1437	283	4	reflection	reflection	NOUN
admet-1437	283	5	xrpd	xrpd	PROPN
admet-1437	283	6	patterns	pattern	NOUN
admet-1437	283	7	between	between	ADP
admet-1437	283	8	10.5	10.5	NUM
admet-1437	283	9	°	°	NOUN
admet-1437	283	10	to	to	ADP
admet-1437	283	11	17.5	17.5	NUM
admet-1437	283	12	°	°	NUM
admet-1437	283	13	2θ	2θ	NUM
admet-1437	283	14	,	,	PUNCT
admet-1437	283	15	with	with	ADP
admet-1437	283	16	100	100	NUM
admet-1437	283	17	%	%	NOUN
admet-1437	283	18	crystalline	crystalline	NOUN
admet-1437	283	19	drug	drug	NOUN
admet-1437	283	20	substance	substance	NOUN
admet-1437	283	21	,	,	PUNCT
admet-1437	283	22	100	100	NUM
admet-1437	283	23	%	%	NOUN
admet-1437	283	24	amorphous	amorphous	ADJ
admet-1437	283	25	drug	drug	NOUN
admet-1437	283	26	substance	substance	NOUN
admet-1437	283	27	and	and	CCONJ
admet-1437	283	28	for	for	ADP
admet-1437	283	29	experiments	experiment	NOUN
admet-1437	283	30	no.1	no.1	NUM
admet-1437	283	31	,	,	PUNCT
admet-1437	283	32	5	5	NUM
admet-1437	283	33	and	and	CCONJ
admet-1437	283	34	8	8	NUM
admet-1437	283	35	with	with	ADP
admet-1437	283	36	particle	particle	NOUN
admet-1437	283	37	size	size	NOUN
admet-1437	283	38	x50,3	x50,3	PROPN
admet-1437	283	39	of	of	ADP
admet-1437	283	40	2443	2443	NUM
admet-1437	283	41	nm	nm	NOUN
admet-1437	283	42	,	,	PUNCT
admet-1437	283	43	111	111	NUM
admet-1437	283	44	nm	nm	NOUN
admet-1437	283	45	and	and	CCONJ
admet-1437	283	46	79	79	NUM
admet-1437	283	47	nm	nm	NOUN
admet-1437	283	48	.	.	PUNCT
admet-1437	284	1	figure	figure	NOUN
admet-1437	284	2	6	6	NUM
admet-1437	284	3	.	.	PUNCT
admet-1437	285	1	calibration	calibration	NOUN
admet-1437	285	2	line	line	NOUN
admet-1437	285	3	at	at	ADP
admet-1437	285	4	16.9994	16.9994	NUM
admet-1437	285	5	°	°	NOUN
admet-1437	285	6	2θ	2θ	NUM
admet-1437	285	7	by	by	ADP
admet-1437	285	8	reflection	reflection	NOUN
admet-1437	285	9	xrpd	xrpd	PROPN
admet-1437	285	10	for	for	ADP
admet-1437	285	11	the	the	DET
admet-1437	285	12	calculation	calculation	NOUN
admet-1437	285	13	of	of	ADP
admet-1437	285	14	the	the	DET
admet-1437	285	15	amorphous	amorphous	ADJ
admet-1437	285	16	content	content	NOUN
admet-1437	285	17	(	(	PUNCT
admet-1437	285	18	wcryst	wcryst	NOUN
admet-1437	285	19	,	,	PUNCT
admet-1437	285	20	xrpd	xrpd	PROPN
admet-1437	285	21	)	)	PUNCT
admet-1437	285	22	with	with	ADP
admet-1437	285	23	95	95	NUM
admet-1437	285	24	%	%	NOUN
admet-1437	285	25	-confidence	-confidence	NOUN
admet-1437	285	26	limits	limit	NOUN
admet-1437	285	27	and	and	CCONJ
admet-1437	285	28	results	result	NOUN
admet-1437	285	29	for	for	ADP
admet-1437	285	30	calibration	calibration	NOUN
admet-1437	285	31	points	point	NOUN
admet-1437	285	32	and	and	CCONJ
admet-1437	285	33	experiments	experiment	NOUN
admet-1437	285	34	no.1	no.1	NUM
admet-1437	285	35	,	,	PUNCT
admet-1437	285	36	5	5	NUM
admet-1437	285	37	and	and	CCONJ
admet-1437	285	38	8	8	NUM
admet-1437	285	39	with	with	ADP
admet-1437	285	40	particle	particle	NOUN
admet-1437	285	41	size	size	NOUN
admet-1437	285	42	x50,3	x50,3	PROPN
admet-1437	285	43	of	of	ADP
admet-1437	285	44	2443	2443	NUM
admet-1437	285	45	nm	nm	NOUN
admet-1437	285	46	,	,	PUNCT
admet-1437	285	47	111	111	NUM
admet-1437	285	48	nm	nm	NOUN
admet-1437	285	49	and	and	CCONJ
admet-1437	285	50	79	79	NUM
admet-1437	285	51	nm	nm	NOUN
admet-1437	285	52	.	.	PUNCT
admet-1437	286	1	the	the	DET
admet-1437	286	2	crystalline	crystalline	PROPN
admet-1437	286	3	content	content	NOUN
admet-1437	286	4	(	(	PUNCT
admet-1437	286	5	wcryst	wcryst	NOUN
admet-1437	286	6	,	,	PUNCT
admet-1437	286	7	xrpd	xrpd	PROPN
admet-1437	286	8	)	)	PUNCT
admet-1437	286	9	for	for	ADP
admet-1437	286	10	experiments	experiment	NOUN
admet-1437	286	11	no	no	INTJ
admet-1437	286	12	.	.	NOUN
admet-1437	286	13	1	1	NUM
admet-1437	286	14	,	,	PUNCT
admet-1437	286	15	5	5	NUM
admet-1437	286	16	and	and	CCONJ
admet-1437	286	17	8	8	NUM
admet-1437	286	18	,	,	PUNCT
admet-1437	286	19	as	as	ADV
admet-1437	286	20	well	well	ADV
admet-1437	286	21	as	as	ADP
admet-1437	286	22	the	the	DET
admet-1437	286	23	errors	error	NOUN
admet-1437	286	24	,	,	PUNCT
admet-1437	286	25	were	be	AUX
admet-1437	286	26	calculated	calculate	VERB
admet-1437	286	27	from	from	ADP
admet-1437	286	28	the	the	DET
admet-1437	286	29	regression	regression	NOUN
admet-1437	286	30	parameters	parameter	NOUN
admet-1437	286	31	and	and	CCONJ
admet-1437	286	32	are	be	AUX
admet-1437	286	33	summarized	summarize	VERB
admet-1437	286	34	in	in	ADP
admet-1437	286	35	table	table	NOUN
admet-1437	286	36	5	5	NUM
admet-1437	286	37	.	.	PUNCT
admet-1437	287	1	it	it	PRON
admet-1437	287	2	should	should	AUX
admet-1437	287	3	be	be	AUX
admet-1437	287	4	noted	note	VERB
admet-1437	287	5	that	that	SCONJ
admet-1437	287	6	the	the	DET
admet-1437	287	7	amorphous	amorphous	ADJ
admet-1437	287	8	content	content	NOUN
admet-1437	287	9	(	(	PUNCT
admet-1437	287	10	wamorph	wamorph	ADJ
admet-1437	287	11	,	,	PUNCT
admet-1437	287	12	xrpd	xrpd	ADJ
admet-1437	287	13	)	)	PUNCT
admet-1437	287	14	is	be	AUX
admet-1437	287	15	defined	define	VERB
admet-1437	287	16	according	accord	VERB
admet-1437	287	17	to	to	ADP
admet-1437	287	18	the	the	DET
admet-1437	287	19	following	follow	VERB
admet-1437	287	20	equation	equation	NOUN
admet-1437	287	21	.	.	PUNCT
admet-1437	288	1	𝑤amorph	𝑤amorph	ADV
admet-1437	288	2	,	,	PUNCT
admet-1437	288	3	xrpd	xrpd	PROPN
admet-1437	288	4	=	=	NOUN
admet-1437	288	5	1	1	NUM
admet-1437	288	6	−	−	PROPN
admet-1437	288	7	𝑤cryst	𝑤cryst	NOUN
admet-1437	288	8	,	,	PUNCT
admet-1437	288	9	xrpd	xrpd	PROPN
admet-1437	288	10	(	(	PUNCT
admet-1437	288	11	8)	8)	NUM
admet-1437	288	12	the	the	DET
admet-1437	288	13	intrinsic	intrinsic	ADJ
admet-1437	288	14	amorphous	amorphous	ADJ
admet-1437	288	15	surface	surface	NOUN
admet-1437	288	16	layer	layer	NOUN
admet-1437	288	17	contribution	contribution	NOUN
admet-1437	288	18	for	for	ADP
admet-1437	288	19	a	a	DET
admet-1437	288	20	depth	depth	NOUN
admet-1437	288	21	of	of	ADP
admet-1437	288	22	one	one	NUM
admet-1437	288	23	unit	unit	NOUN
admet-1437	288	24	cell	cell	NOUN
admet-1437	288	25	was	be	AUX
admet-1437	288	26	calculated	calculate	VERB
admet-1437	288	27	using	use	VERB
admet-1437	288	28	the	the	DET
admet-1437	288	29	median	median	ADJ
admet-1437	288	30	particle	particle	NOUN
admet-1437	288	31	size	size	NOUN
admet-1437	288	32	(	(	PUNCT
admet-1437	288	33	wamorph	wamorph	NOUN
admet-1437	288	34	,	,	PUNCT
admet-1437	288	35	z=1	z=1	NUM
admet-1437	288	36	)	)	PUNCT
admet-1437	288	37	,	,	PUNCT
admet-1437	288	38	see	see	VERB
admet-1437	288	39	table	table	NOUN
admet-1437	288	40	5	5	NUM
admet-1437	288	41	.	.	PUNCT
admet-1437	288	42	results	result	NOUN
admet-1437	288	43	for	for	ADP
admet-1437	288	44	the	the	DET
admet-1437	288	45	micron	micron	NOUN
admet-1437	288	46	-	-	PUNCT
admet-1437	288	47	sized	sized	ADJ
admet-1437	288	48	drug	drug	NOUN
admet-1437	288	49	substance	substance	NOUN
admet-1437	288	50	and	and	CCONJ
admet-1437	288	51	the	the	DET
admet-1437	288	52	nanocrystal	nanocrystal	ADJ
admet-1437	288	53	drug	drug	NOUN
admet-1437	288	54	substance	substance	NOUN
admet-1437	288	55	batches	batch	NOUN
admet-1437	288	56	cluster	cluster	NOUN
admet-1437	288	57	separately	separately	ADV
admet-1437	288	58	,	,	PUNCT
admet-1437	288	59	suggesting	suggest	VERB
admet-1437	288	60	that	that	SCONJ
admet-1437	288	61	the	the	DET
admet-1437	288	62	nanocrystals	nanocrystal	NOUN
admet-1437	288	63	do	do	AUX
admet-1437	288	64	have	have	VERB
admet-1437	288	65	a	a	DET
admet-1437	288	66	higher	high	ADJ
admet-1437	288	67	amorphous	amorphous	ADJ
admet-1437	288	68	content	content	NOUN
admet-1437	288	69	than	than	ADP
admet-1437	288	70	the	the	DET
admet-1437	288	71	micron	micron	NOUN
admet-1437	288	72	-	-	PUNCT
admet-1437	288	73	sized	sized	ADJ
admet-1437	288	74	drug	drug	NOUN
admet-1437	288	75	substance	substance	NOUN
admet-1437	288	76	.	.	PUNCT
admet-1437	289	1	within	within	ADP
admet-1437	289	2	the	the	DET
admet-1437	289	3	error	error	NOUN
admet-1437	289	4	limits	limit	NOUN
admet-1437	289	5	,	,	PUNCT
admet-1437	289	6	the	the	DET
admet-1437	289	7	micron	micron	NOUN
admet-1437	289	8	-	-	PUNCT
admet-1437	289	9	sized	sized	ADJ
admet-1437	289	10	drug	drug	NOUN
admet-1437	289	11	substance	substance	NOUN
admet-1437	289	12	shows	show	VERB
admet-1437	289	13	an	an	DET
admet-1437	289	14	amorphous	amorphous	ADJ
admet-1437	289	15	content	content	NOUN
admet-1437	289	16	of	of	ADP
admet-1437	289	17	8	8	NUM
admet-1437	289	18	%	%	NOUN
admet-1437	289	19	w	w	NOUN
admet-1437	289	20	,	,	PUNCT
admet-1437	289	21	while	while	SCONJ
admet-1437	289	22	the	the	DET
admet-1437	289	23	nanocrystal	nanocrystal	ADJ
admet-1437	289	24	drug	drug	NOUN
admet-1437	289	25	substance	substance	NOUN
admet-1437	289	26	batches	batch	NOUN
admet-1437	289	27	show	show	VERB
admet-1437	289	28	an	an	DET
admet-1437	289	29	amorphous	amorphous	ADJ
admet-1437	289	30	content	content	NOUN
admet-1437	289	31	of	of	ADP
admet-1437	289	32	21.5	21.5	NUM
admet-1437	289	33	%	%	NOUN
admet-1437	289	34	w	w	NOUN
admet-1437	289	35	on	on	ADP
admet-1437	289	36	average	average	ADJ
admet-1437	289	37	.	.	PUNCT
admet-1437	290	1	both	both	DET
admet-1437	290	2	values	value	NOUN
admet-1437	290	3	are	be	AUX
admet-1437	290	4	significantly	significantly	ADV
admet-1437	290	5	larger	large	ADJ
admet-1437	290	6	than	than	ADP
admet-1437	290	7	those	those	PRON
admet-1437	290	8	suggested	suggest	VERB
admet-1437	290	9	by	by	ADP
admet-1437	290	10	assuming	assume	VERB
admet-1437	290	11	a	a	DET
admet-1437	290	12	single	single	ADJ
admet-1437	290	13	amorphous	amorphous	ADJ
admet-1437	290	14	surface	surface	NOUN
admet-1437	290	15	layer	layer	NOUN
admet-1437	290	16	of	of	ADP
admet-1437	290	17	unit	unit	NOUN
admet-1437	290	18	cells	cell	NOUN
admet-1437	290	19	,	,	PUNCT
admet-1437	290	20	see	see	VERB
admet-1437	290	21	table	table	NOUN
admet-1437	290	22	5	5	NUM
admet-1437	290	23	.	.	PUNCT
admet-1437	291	1	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	NOUN
admet-1437	291	2	bonhoeffer	bonhoeffer	PROPN
admet-1437	291	3	et	et	PROPN
admet-1437	291	4	al	al	PROPN
admet-1437	291	5	.	.	PROPN
admet-1437	291	6	admet	admet	PROPN
admet-1437	291	7	&	&	CCONJ
admet-1437	291	8	dmpk	dmpk	PROPN
admet-1437	291	9	10(4	10(4	NUM
admet-1437	291	10	)	)	PUNCT
admet-1437	291	11	(	(	PUNCT
admet-1437	291	12	2022	2022	NUM
admet-1437	291	13	)	)	PUNCT
admet-1437	291	14	253	253	NUM
admet-1437	291	15	-	-	SYM
admet-1437	291	16	287	287	NUM
admet-1437	291	17	268	268	NUM
admet-1437	291	18	table	table	NOUN
admet-1437	291	19	5	5	NUM
admet-1437	291	20	.	.	PUNCT
admet-1437	291	21	calculated	calculate	VERB
admet-1437	291	22	crystalline	crystalline	NOUN
admet-1437	291	23	content	content	NOUN
admet-1437	291	24	(	(	PUNCT
admet-1437	291	25	wcryst	wcryst	NOUN
admet-1437	291	26	,	,	PUNCT
admet-1437	291	27	xrpd	xrpd	ADJ
admet-1437	291	28	)	)	PUNCT
admet-1437	291	29	and	and	CCONJ
admet-1437	291	30	amorphous	amorphous	ADJ
admet-1437	291	31	content	content	NOUN
admet-1437	291	32	(	(	PUNCT
admet-1437	291	33	wamorph	wamorph	ADJ
admet-1437	291	34	,	,	PUNCT
admet-1437	291	35	xrpd	xrpd	ADJ
admet-1437	291	36	)	)	PUNCT
admet-1437	291	37	by	by	ADP
admet-1437	291	38	reflection	reflection	NOUN
admet-1437	291	39	xrpd	xrpd	PROPN
admet-1437	291	40	for	for	ADP
admet-1437	291	41	experiment	experiment	NOUN
admet-1437	291	42	no.1	no.1	VERB
admet-1437	291	43	,	,	PUNCT
admet-1437	291	44	5	5	NUM
admet-1437	291	45	and	and	CCONJ
admet-1437	291	46	8	8	NUM
admet-1437	291	47	and	and	CCONJ
admet-1437	291	48	calculated	calculate	VERB
admet-1437	291	49	amorphous	amorphous	ADJ
admet-1437	291	50	content	content	NOUN
admet-1437	291	51	for	for	ADP
admet-1437	291	52	a	a	DET
admet-1437	291	53	single	single	ADJ
admet-1437	291	54	layer	layer	NOUN
admet-1437	291	55	of	of	ADP
admet-1437	291	56	unit	unit	NOUN
admet-1437	291	57	cell	cell	NOUN
admet-1437	291	58	and	and	CCONJ
admet-1437	291	59	related	related	ADJ
admet-1437	291	60	median	median	ADJ
admet-1437	291	61	particle	particle	NOUN
admet-1437	291	62	size	size	NOUN
admet-1437	291	63	x50,3	x50,3	PROPN
admet-1437	291	64	(	(	PUNCT
admet-1437	291	65	wamorph	wamorph	NOUN
admet-1437	291	66	,	,	PUNCT
admet-1437	291	67	z=1	z=1	NUM
admet-1437	291	68	)	)	PUNCT
admet-1437	291	69	.	.	PUNCT
admet-1437	292	1	experiment	experiment	NOUN
admet-1437	292	2	no	no	PROPN
admet-1437	292	3	.	.	PUNCT
admet-1437	292	4	particle	particle	NOUN
admet-1437	292	5	size	size	NOUN
admet-1437	292	6	x50,3	x50,3	PROPN
admet-1437	292	7	/	/	SYM
admet-1437	292	8	nm	nm	PROPN
admet-1437	292	9	wcryst	wcryst	NOUN
admet-1437	292	10	,	,	PUNCT
admet-1437	292	11	xrpd	xrpd	PROPN
admet-1437	292	12	/	/	SYM
admet-1437	292	13	%	%	NOUN
admet-1437	292	14	wamorph	wamorph	ADJ
admet-1437	292	15	,	,	PUNCT
admet-1437	292	16	xrpd	xrpd	ADJ
admet-1437	292	17	/	/	SYM
admet-1437	292	18	%	%	NOUN
admet-1437	292	19	wamorph	wamorph	NOUN
admet-1437	292	20	z=1	z=1	NOUN
admet-1437	292	21	/	/	SYM
admet-1437	292	22	%	%	NOUN
admet-1437	293	1	1	1	NUM
admet-1437	293	2	2443	2443	NUM
admet-1437	293	3	92	92	NUM
admet-1437	293	4	±1	±1	VERB
admet-1437	293	5	8	8	NUM
admet-1437	293	6	0.3	0.3	NUM
admet-1437	293	7	5	5	NUM
admet-1437	293	8	111	111	NUM
admet-1437	293	9	77	77	NUM
admet-1437	293	10	±3	±3	ADJ
admet-1437	293	11	23	23	NUM
admet-1437	293	12	5.6	5.6	NUM
admet-1437	293	13	8	8	NUM
admet-1437	293	14	79	79	NUM
admet-1437	293	15	80	80	NUM
admet-1437	293	16	±3	±3	ADJ
admet-1437	293	17	20	20	NUM
admet-1437	293	18	7.8	7.8	NUM
admet-1437	293	19	the	the	DET
admet-1437	293	20	contribution	contribution	NOUN
admet-1437	293	21	from	from	ADP
admet-1437	293	22	the	the	DET
admet-1437	293	23	nanocrystals	nanocrystal	NOUN
admet-1437	293	24	to	to	ADP
admet-1437	293	25	the	the	DET
admet-1437	293	26	estimated	estimate	VERB
admet-1437	293	27	intrinsic	intrinsic	ADJ
admet-1437	293	28	surface	surface	NOUN
admet-1437	293	29	amorphicity	amorphicity	NOUN
admet-1437	293	30	can	can	AUX
admet-1437	293	31	be	be	AUX
admet-1437	293	32	calculated	calculate	VERB
admet-1437	293	33	by	by	ADP
admet-1437	293	34	taking	take	VERB
admet-1437	293	35	the	the	DET
admet-1437	293	36	whole	whole	ADJ
admet-1437	293	37	particle	particle	NOUN
admet-1437	293	38	size	size	NOUN
admet-1437	293	39	distribution	distribution	NOUN
admet-1437	293	40	from	from	ADP
admet-1437	293	41	table	table	NOUN
admet-1437	293	42	2	2	NUM
admet-1437	293	43	into	into	ADP
admet-1437	293	44	account	account	NOUN
admet-1437	293	45	.	.	PUNCT
admet-1437	294	1	this	this	PRON
admet-1437	294	2	should	should	AUX
admet-1437	294	3	give	give	VERB
admet-1437	294	4	a	a	DET
admet-1437	294	5	more	more	ADV
admet-1437	294	6	accurate	accurate	ADJ
admet-1437	294	7	estimate	estimate	NOUN
admet-1437	294	8	of	of	ADP
admet-1437	294	9	the	the	DET
admet-1437	294	10	intrinsic	intrinsic	ADJ
admet-1437	294	11	surface	surface	NOUN
admet-1437	294	12	amorphicity	amorphicity	NOUN
admet-1437	294	13	.	.	PUNCT
admet-1437	295	1	assuming	assume	VERB
admet-1437	295	2	several	several	ADJ
admet-1437	295	3	layers	layer	NOUN
admet-1437	295	4	of	of	ADP
admet-1437	295	5	non	non	ADJ
admet-1437	295	6	-	-	ADJ
admet-1437	295	7	crystalline	crystalline	ADJ
admet-1437	295	8	surface	surface	NOUN
admet-1437	295	9	unit	unit	NOUN
admet-1437	295	10	cells	cell	NOUN
admet-1437	295	11	(	(	PUNCT
admet-1437	295	12	z	z	NOUN
admet-1437	295	13	)	)	PUNCT
admet-1437	295	14	,	,	PUNCT
admet-1437	295	15	the	the	DET
admet-1437	295	16	intrinsic	intrinsic	ADJ
admet-1437	295	17	surface	surface	NOUN
admet-1437	295	18	amorphicity	amorphicity	NOUN
admet-1437	295	19	(	(	PUNCT
admet-1437	295	20	wamorph	wamorph	NOUN
admet-1437	295	21	,	,	PUNCT
admet-1437	295	22	z	z	NOUN
admet-1437	295	23	)	)	PUNCT
admet-1437	295	24	contribution	contribution	NOUN
admet-1437	295	25	rises	rise	VERB
admet-1437	295	26	significantly	significantly	ADV
admet-1437	295	27	depending	depend	VERB
admet-1437	295	28	on	on	ADP
admet-1437	295	29	the	the	DET
admet-1437	295	30	number	number	NOUN
admet-1437	295	31	of	of	ADP
admet-1437	295	32	layers	layer	NOUN
admet-1437	295	33	of	of	ADP
admet-1437	295	34	unit	unit	NOUN
admet-1437	295	35	cells	cell	NOUN
admet-1437	295	36	.	.	PUNCT
admet-1437	296	1	it	it	PRON
admet-1437	296	2	should	should	AUX
admet-1437	296	3	also	also	ADV
admet-1437	296	4	be	be	AUX
admet-1437	296	5	kept	keep	VERB
admet-1437	296	6	in	in	ADP
admet-1437	296	7	mind	mind	NOUN
admet-1437	296	8	that	that	SCONJ
admet-1437	296	9	the	the	DET
admet-1437	296	10	limit	limit	NOUN
admet-1437	296	11	of	of	ADP
admet-1437	296	12	detection	detection	NOUN
admet-1437	296	13	of	of	ADP
admet-1437	296	14	crystallinity	crystallinity	NOUN
admet-1437	296	15	,	,	PUNCT
admet-1437	296	16	determined	determine	VERB
admet-1437	296	17	by	by	ADP
admet-1437	296	18	reflection	reflection	NOUN
admet-1437	296	19	xrpd	xrpd	PROPN
admet-1437	296	20	,	,	PUNCT
admet-1437	296	21	suggests	suggest	VERB
admet-1437	296	22	that	that	SCONJ
admet-1437	296	23	particles	particle	NOUN
admet-1437	296	24	in	in	ADP
admet-1437	296	25	that	that	DET
admet-1437	296	26	size	size	NOUN
admet-1437	296	27	range	range	NOUN
admet-1437	296	28	might	might	AUX
admet-1437	296	29	still	still	ADV
admet-1437	296	30	be	be	AUX
admet-1437	296	31	crystalline	crystalline	ADJ
admet-1437	296	32	,	,	PUNCT
admet-1437	296	33	although	although	SCONJ
admet-1437	296	34	appearing	appear	VERB
admet-1437	296	35	amorphous	amorphous	ADJ
admet-1437	296	36	in	in	ADP
admet-1437	296	37	the	the	DET
admet-1437	296	38	measurement	measurement	NOUN
admet-1437	296	39	.	.	PUNCT
admet-1437	297	1	therefore	therefore	ADV
admet-1437	297	2	,	,	PUNCT
admet-1437	297	3	the	the	DET
admet-1437	297	4	true	true	ADJ
admet-1437	297	5	amount	amount	NOUN
admet-1437	297	6	of	of	ADP
admet-1437	297	7	amorphicity	amorphicity	NOUN
admet-1437	297	8	could	could	AUX
admet-1437	297	9	be	be	AUX
admet-1437	297	10	less	less	ADJ
admet-1437	297	11	than	than	ADP
admet-1437	297	12	the	the	DET
admet-1437	297	13	measured	measure	VERB
admet-1437	297	14	one	one	NUM
admet-1437	297	15	.	.	PUNCT
admet-1437	298	1	the	the	DET
admet-1437	298	2	nanocrystal	nanocrystal	ADJ
admet-1437	298	3	particle	particle	NOUN
admet-1437	298	4	size	size	NOUN
admet-1437	298	5	distribution	distribution	NOUN
admet-1437	298	6	data	datum	NOUN
admet-1437	298	7	suggests	suggest	VERB
admet-1437	298	8	that	that	SCONJ
admet-1437	298	9	no	no	DET
admet-1437	298	10	more	more	ADJ
admet-1437	298	11	than	than	ADP
admet-1437	298	12	1	1	NUM
admet-1437	298	13	%	%	NOUN
admet-1437	298	14	w	w	NOUN
admet-1437	298	15	of	of	ADP
admet-1437	298	16	the	the	DET
admet-1437	298	17	particles	particle	NOUN
admet-1437	298	18	would	would	AUX
admet-1437	298	19	fall	fall	VERB
admet-1437	298	20	into	into	ADP
admet-1437	298	21	the	the	DET
admet-1437	298	22	size	size	NOUN
admet-1437	298	23	range	range	NOUN
admet-1437	298	24	below	below	ADP
admet-1437	298	25	20	20	NUM
admet-1437	298	26	to	to	PART
admet-1437	298	27	30	30	NUM
admet-1437	298	28	nm	nm	NOUN
admet-1437	298	29	for	for	ADP
admet-1437	298	30	the	the	DET
admet-1437	298	31	smallest	small	ADJ
admet-1437	298	32	average	average	ADJ
admet-1437	298	33	particle	particle	NOUN
admet-1437	298	34	size	size	NOUN
admet-1437	298	35	,	,	PUNCT
admet-1437	298	36	i.e.	i.e.	X
admet-1437	298	37	,	,	PUNCT
admet-1437	298	38	experiment	experiment	NOUN
admet-1437	298	39	no	no	NOUN
admet-1437	298	40	.	.	NOUN
admet-1437	298	41	8	8	NUM
admet-1437	298	42	.	.	NOUN
admet-1437	298	43	table	table	NOUN
admet-1437	298	44	6	6	NUM
admet-1437	298	45	.	.	PUNCT
admet-1437	298	46	estimated	estimate	VERB
admet-1437	298	47	relative	relative	ADJ
admet-1437	298	48	amount	amount	NOUN
admet-1437	298	49	of	of	ADP
admet-1437	298	50	the	the	DET
admet-1437	298	51	amorphous	amorphous	ADJ
admet-1437	298	52	content	content	NOUN
admet-1437	298	53	(	(	PUNCT
admet-1437	298	54	wamorph	wamorph	ADJ
admet-1437	298	55	,	,	PUNCT
admet-1437	298	56	z	z	NOUN
admet-1437	298	57	)	)	PUNCT
admet-1437	298	58	for	for	ADP
admet-1437	298	59	experiments	experiment	NOUN
admet-1437	298	60	no	no	INTJ
admet-1437	298	61	.	.	NOUN
admet-1437	298	62	5	5	NUM
admet-1437	298	63	and	and	CCONJ
admet-1437	298	64	8	8	NUM
admet-1437	298	65	considering	consider	VERB
admet-1437	298	66	the	the	DET
admet-1437	298	67	whole	whole	ADJ
admet-1437	298	68	particle	particle	NOUN
admet-1437	298	69	size	size	NOUN
admet-1437	298	70	distribution	distribution	NOUN
admet-1437	298	71	and	and	CCONJ
admet-1437	298	72	a	a	DET
admet-1437	298	73	different	different	ADJ
admet-1437	298	74	number	number	NOUN
admet-1437	298	75	of	of	ADP
admet-1437	298	76	layers	layer	NOUN
admet-1437	298	77	of	of	ADP
admet-1437	298	78	unit	unit	NOUN
admet-1437	298	79	cells	cell	NOUN
admet-1437	298	80	(	(	PUNCT
admet-1437	298	81	z	z	NOUN
admet-1437	298	82	)	)	PUNCT
admet-1437	298	83	.	.	PUNCT
admet-1437	299	1	experiment	experiment	NOUN
admet-1437	299	2	no	no	PROPN
admet-1437	299	3	.	.	PUNCT
admet-1437	299	4	particle	particle	NOUN
admet-1437	299	5	size	size	NOUN
admet-1437	299	6	x50,3	x50,3	PROPN
admet-1437	299	7	/	/	SYM
admet-1437	299	8	nm	nm	ADV
admet-1437	299	9	amorphous	amorphous	ADJ
admet-1437	299	10	content	content	NOUN
admet-1437	299	11	wamorph	wamorph	NOUN
admet-1437	299	12	,	,	PUNCT
admet-1437	299	13	z	z	NOUN
admet-1437	299	14	/	/	SYM
admet-1437	299	15	%	%	NOUN
admet-1437	300	1	z=1	z=1	PUNCT
admet-1437	300	2	z=2	z=2	PUNCT
admet-1437	300	3	z=3	z=3	NUM
admet-1437	300	4	5	5	NUM
admet-1437	300	5	111	111	NUM
admet-1437	300	6	6.3	6.3	NUM
admet-1437	300	7	12.3	12.3	NUM
admet-1437	300	8	17.9	17.9	NUM
admet-1437	300	9	8	8	NUM
admet-1437	300	10	79	79	NUM
admet-1437	300	11	9.0	9.0	NUM
admet-1437	300	12	17.4	17.4	NUM
admet-1437	300	13	25.1	25.1	NUM
admet-1437	300	14	the	the	DET
admet-1437	300	15	difference	difference	NOUN
admet-1437	300	16	between	between	ADP
admet-1437	300	17	the	the	DET
admet-1437	300	18	estimated	estimate	VERB
admet-1437	300	19	intrinsic	intrinsic	ADJ
admet-1437	300	20	surface	surface	NOUN
admet-1437	300	21	amorphicity	amorphicity	NOUN
admet-1437	300	22	for	for	ADP
admet-1437	300	23	a	a	DET
admet-1437	300	24	single	single	ADJ
admet-1437	300	25	amorphous	amorphous	ADJ
admet-1437	300	26	layer	layer	NOUN
admet-1437	300	27	and	and	CCONJ
admet-1437	300	28	the	the	DET
admet-1437	300	29	calculated	calculate	VERB
admet-1437	300	30	amorphicity	amorphicity	NOUN
admet-1437	300	31	based	base	VERB
admet-1437	300	32	on	on	ADP
admet-1437	300	33	xrpd	xrpd	ADJ
admet-1437	300	34	measurements	measurement	NOUN
admet-1437	300	35	is	be	AUX
admet-1437	300	36	only	only	ADV
admet-1437	300	37	about	about	ADP
admet-1437	300	38	a	a	DET
admet-1437	300	39	factor	factor	NOUN
admet-1437	300	40	of	of	ADP
admet-1437	300	41	2	2	NUM
admet-1437	300	42	to	to	ADP
admet-1437	300	43	4	4	NUM
admet-1437	300	44	for	for	ADP
admet-1437	300	45	nanocrystals	nanocrystal	NOUN
admet-1437	300	46	and	and	CCONJ
admet-1437	300	47	is	be	AUX
admet-1437	300	48	therefore	therefore	ADV
admet-1437	300	49	reasonable	reasonable	ADJ
admet-1437	300	50	,	,	PUNCT
admet-1437	300	51	see	see	VERB
admet-1437	300	52	experiment	experiment	NOUN
admet-1437	300	53	no	no	NOUN
admet-1437	300	54	.	.	NOUN
admet-1437	300	55	5	5	NUM
admet-1437	300	56	and	and	CCONJ
admet-1437	300	57	8	8	NUM
admet-1437	300	58	in	in	ADP
admet-1437	300	59	table	table	NOUN
admet-1437	300	60	5	5	NUM
admet-1437	300	61	and	and	CCONJ
admet-1437	300	62	table	table	NOUN
admet-1437	300	63	6	6	NUM
admet-1437	300	64	.	.	PUNCT
admet-1437	301	1	however	however	ADV
admet-1437	301	2	,	,	PUNCT
admet-1437	301	3	it	it	PRON
admet-1437	301	4	is	be	AUX
admet-1437	301	5	more	more	ADV
admet-1437	301	6	prudent	prudent	ADJ
admet-1437	301	7	to	to	PART
admet-1437	301	8	assume	assume	VERB
admet-1437	301	9	that	that	SCONJ
admet-1437	301	10	the	the	DET
admet-1437	301	11	high	high	ADJ
admet-1437	301	12	curvature	curvature	NOUN
admet-1437	301	13	of	of	ADP
admet-1437	301	14	the	the	DET
admet-1437	301	15	nanocrystal	nanocrystal	ADJ
admet-1437	301	16	particles	particle	NOUN
admet-1437	301	17	might	might	AUX
admet-1437	301	18	impact	impact	VERB
admet-1437	301	19	the	the	DET
admet-1437	301	20	crystal	crystal	NOUN
admet-1437	301	21	structure	structure	NOUN
admet-1437	301	22	deeper	deeply	ADV
admet-1437	301	23	than	than	ADP
admet-1437	301	24	just	just	ADV
admet-1437	301	25	the	the	DET
admet-1437	301	26	mere	mere	ADJ
admet-1437	301	27	surface	surface	NOUN
admet-1437	301	28	and	and	CCONJ
admet-1437	301	29	at	at	ADV
admet-1437	301	30	least	least	ADV
admet-1437	301	31	1	1	NUM
admet-1437	301	32	or	or	CCONJ
admet-1437	301	33	2	2	NUM
admet-1437	301	34	additional	additional	ADJ
admet-1437	301	35	layers	layer	NOUN
admet-1437	301	36	are	be	AUX
admet-1437	301	37	affected	affect	VERB
admet-1437	301	38	.	.	PUNCT
admet-1437	302	1	indeed	indeed	ADV
admet-1437	302	2	with	with	ADP
admet-1437	302	3	z=3	z=3	PROPN
admet-1437	302	4	,	,	PUNCT
admet-1437	302	5	there	there	PRON
admet-1437	302	6	is	be	VERB
admet-1437	302	7	a	a	DET
admet-1437	302	8	good	good	ADJ
admet-1437	302	9	match	match	NOUN
admet-1437	302	10	between	between	ADP
admet-1437	302	11	calculated	calculate	VERB
admet-1437	302	12	and	and	CCONJ
admet-1437	302	13	measured	measure	VERB
admet-1437	302	14	amorphous	amorphous	ADJ
admet-1437	302	15	content	content	NOUN
admet-1437	302	16	.	.	PUNCT
admet-1437	303	1	it	it	PRON
admet-1437	303	2	should	should	AUX
admet-1437	303	3	be	be	AUX
admet-1437	303	4	kept	keep	VERB
admet-1437	303	5	in	in	ADP
admet-1437	303	6	mind	mind	NOUN
admet-1437	303	7	that	that	SCONJ
admet-1437	303	8	a	a	DET
admet-1437	303	9	depth	depth	NOUN
admet-1437	303	10	of	of	ADP
admet-1437	303	11	three	three	NUM
admet-1437	303	12	unit	unit	NOUN
admet-1437	303	13	cells	cell	NOUN
admet-1437	303	14	would	would	AUX
admet-1437	303	15	only	only	ADV
admet-1437	303	16	correspond	correspond	VERB
admet-1437	303	17	to	to	ADP
admet-1437	303	18	about	about	ADV
admet-1437	303	19	3.3	3.3	NUM
admet-1437	303	20	nm	nm	NOUN
admet-1437	303	21	.	.	PUNCT
admet-1437	304	1	on	on	ADP
admet-1437	304	2	the	the	DET
admet-1437	304	3	other	other	ADJ
admet-1437	304	4	hand	hand	NOUN
admet-1437	304	5	,	,	PUNCT
admet-1437	304	6	the	the	DET
admet-1437	304	7	large	large	ADJ
admet-1437	304	8	discrepancy	discrepancy	NOUN
admet-1437	304	9	between	between	ADP
admet-1437	304	10	xrpd	xrpd	ADJ
admet-1437	304	11	measurements	measurement	NOUN
admet-1437	304	12	and	and	CCONJ
admet-1437	304	13	the	the	DET
admet-1437	304	14	estimation	estimation	NOUN
admet-1437	304	15	for	for	ADP
admet-1437	304	16	the	the	DET
admet-1437	304	17	micron	micron	NOUN
admet-1437	304	18	-	-	PUNCT
admet-1437	304	19	sized	sized	ADJ
admet-1437	304	20	coarse	coarse	ADJ
admet-1437	304	21	crystals	crystal	NOUN
admet-1437	304	22	by	by	ADP
admet-1437	304	23	a	a	DET
admet-1437	304	24	factor	factor	NOUN
admet-1437	304	25	of	of	ADP
admet-1437	304	26	27	27	NUM
admet-1437	304	27	is	be	AUX
admet-1437	304	28	striking	striking	ADJ
admet-1437	304	29	,	,	PUNCT
admet-1437	304	30	see	see	VERB
admet-1437	304	31	experiment	experiment	NOUN
admet-1437	304	32	no	no	NOUN
admet-1437	304	33	.	.	NOUN
admet-1437	304	34	1	1	NUM
admet-1437	304	35	in	in	ADP
admet-1437	304	36	table	table	NOUN
admet-1437	304	37	5	5	NUM
admet-1437	304	38	.	.	PUNCT
admet-1437	305	1	the	the	DET
admet-1437	305	2	material	material	NOUN
admet-1437	305	3	was	be	AUX
admet-1437	305	4	processed	process	VERB
admet-1437	305	5	by	by	ADP
admet-1437	305	6	dry	dry	ADJ
admet-1437	305	7	jet	jet	NOUN
admet-1437	305	8	milling	milling	NOUN
admet-1437	305	9	.	.	PUNCT
admet-1437	306	1	this	this	DET
admet-1437	306	2	process	process	NOUN
admet-1437	306	3	is	be	AUX
admet-1437	306	4	operated	operate	VERB
admet-1437	306	5	in	in	ADP
admet-1437	306	6	a	a	DET
admet-1437	306	7	gaseous	gaseous	ADJ
admet-1437	306	8	atmosphere	atmosphere	NOUN
admet-1437	306	9	and	and	CCONJ
admet-1437	306	10	breakage	breakage	NOUN
admet-1437	306	11	is	be	AUX
admet-1437	306	12	obtained	obtain	VERB
admet-1437	306	13	by	by	ADP
admet-1437	306	14	elastic	elastic	ADJ
admet-1437	306	15	and	and	CCONJ
admet-1437	306	16	elastic	elastic	ADJ
admet-1437	306	17	-	-	PUNCT
admet-1437	306	18	plastic	plastic	NOUN
admet-1437	306	19	deformation	deformation	NOUN
admet-1437	306	20	.	.	PUNCT
admet-1437	307	1	therefore	therefore	ADV
admet-1437	307	2	,	,	PUNCT
admet-1437	307	3	damaged	damage	VERB
admet-1437	307	4	material	material	NOUN
admet-1437	307	5	may	may	AUX
admet-1437	307	6	be	be	AUX
admet-1437	307	7	able	able	ADJ
admet-1437	307	8	to	to	PART
admet-1437	307	9	recrystallize	recrystallize	VERB
admet-1437	307	10	by	by	ADP
admet-1437	307	11	its	its	PRON
admet-1437	307	12	intrinsic	intrinsic	ADJ
admet-1437	307	13	properties	property	NOUN
admet-1437	307	14	and	and	CCONJ
admet-1437	307	15	elevated	elevated	ADJ
admet-1437	307	16	surface	surface	NOUN
admet-1437	307	17	temperature	temperature	NOUN
admet-1437	307	18	from	from	ADP
admet-1437	307	19	the	the	DET
admet-1437	307	20	moving	move	VERB
admet-1437	307	21	crack	crack	NOUN
admet-1437	307	22	.	.	PUNCT
admet-1437	308	1	in	in	ADP
admet-1437	308	2	contrast	contrast	NOUN
admet-1437	308	3	,	,	PUNCT
admet-1437	308	4	nanocrystals	nanocrystal	NOUN
admet-1437	308	5	were	be	AUX
admet-1437	308	6	manufactured	manufacture	VERB
admet-1437	308	7	by	by	ADP
admet-1437	308	8	wet	wet	ADJ
admet-1437	308	9	-	-	PUNCT
admet-1437	308	10	media	medium	NOUN
admet-1437	308	11	milling	milling	NOUN
admet-1437	308	12	,	,	PUNCT
admet-1437	308	13	which	which	PRON
admet-1437	308	14	is	be	AUX
admet-1437	308	15	operated	operate	VERB
admet-1437	308	16	in	in	ADP
admet-1437	308	17	a	a	DET
admet-1437	308	18	liquid	liquid	ADJ
admet-1437	308	19	medium	medium	NOUN
admet-1437	308	20	and	and	CCONJ
admet-1437	308	21	breakage	breakage	NOUN
admet-1437	308	22	can	can	AUX
admet-1437	308	23	be	be	AUX
admet-1437	308	24	assumed	assume	VERB
admet-1437	308	25	to	to	PART
admet-1437	308	26	take	take	VERB
admet-1437	308	27	place	place	NOUN
admet-1437	308	28	for	for	ADP
admet-1437	308	29	submicron	submicron	NOUN
admet-1437	308	30	-	-	PUNCT
admet-1437	308	31	sized	sized	ADJ
admet-1437	308	32	particles	particle	NOUN
admet-1437	308	33	by	by	ADP
admet-1437	308	34	plastic	plastic	ADJ
admet-1437	308	35	deformation	deformation	NOUN
admet-1437	308	36	.	.	PUNCT
admet-1437	309	1	damaged	damage	VERB
admet-1437	309	2	material	material	NOUN
admet-1437	309	3	may	may	AUX
admet-1437	309	4	be	be	AUX
admet-1437	309	5	able	able	ADJ
admet-1437	309	6	to	to	PART
admet-1437	309	7	recrystallize	recrystallize	VERB
admet-1437	309	8	by	by	ADP
admet-1437	309	9	its	its	PRON
admet-1437	309	10	intrinsic	intrinsic	ADJ
admet-1437	309	11	properties	property	NOUN
admet-1437	309	12	but	but	CCONJ
admet-1437	309	13	also	also	ADV
admet-1437	309	14	by	by	ADP
admet-1437	309	15	solubilization	solubilization	NOUN
admet-1437	309	16	and	and	CCONJ
admet-1437	309	17	precipitation	precipitation	NOUN
admet-1437	309	18	at	at	ADP
admet-1437	309	19	the	the	DET
admet-1437	309	20	solid	solid	ADJ
admet-1437	309	21	-	-	PUNCT
admet-1437	309	22	liquid	liquid	ADJ
admet-1437	309	23	interface	interface	NOUN
admet-1437	309	24	[	[	X
admet-1437	309	25	81	81	NUM
admet-1437	309	26	]	]	PUNCT
admet-1437	309	27	.	.	PUNCT
admet-1437	310	1	unfortunately	unfortunately	ADV
admet-1437	310	2	,	,	PUNCT
admet-1437	310	3	the	the	DET
admet-1437	310	4	interplay	interplay	NOUN
admet-1437	310	5	of	of	ADP
admet-1437	310	6	the	the	DET
admet-1437	310	7	different	different	ADJ
admet-1437	310	8	phenomena	phenomenon	NOUN
admet-1437	310	9	and	and	CCONJ
admet-1437	310	10	resulting	result	VERB
admet-1437	310	11	product	product	NOUN
admet-1437	310	12	properties	property	NOUN
admet-1437	310	13	is	be	AUX
admet-1437	310	14	not	not	PART
admet-1437	310	15	understood	understand	VERB
admet-1437	310	16	for	for	ADP
admet-1437	310	17	dry	dry	ADJ
admet-1437	310	18	-	-	PUNCT
admet-1437	310	19	jet	jet	NOUN
admet-1437	310	20	milling	milling	NOUN
admet-1437	310	21	and	and	CCONJ
admet-1437	310	22	wet	wet	ADJ
admet-1437	310	23	-	-	PUNCT
admet-1437	310	24	media	medium	NOUN
admet-1437	310	25	milling	milling	NOUN
admet-1437	310	26	.	.	PUNCT
admet-1437	311	1	however	however	ADV
admet-1437	311	2	,	,	PUNCT
admet-1437	311	3	considering	consider	VERB
admet-1437	311	4	the	the	DET
admet-1437	311	5	theoretical	theoretical	ADJ
admet-1437	311	6	model	model	NOUN
admet-1437	311	7	outlined	outline	VERB
admet-1437	311	8	earlier	early	ADV
admet-1437	311	9	,	,	PUNCT
admet-1437	311	10	the	the	DET
admet-1437	311	11	obtained	obtain	VERB
admet-1437	311	12	results	result	NOUN
admet-1437	311	13	for	for	ADP
admet-1437	311	14	dry	dry	ADJ
admet-1437	311	15	-	-	PUNCT
admet-1437	311	16	jet	jet	NOUN
admet-1437	311	17	milled	mill	VERB
admet-1437	311	18	particles	particle	NOUN
admet-1437	311	19	suggest	suggest	VERB
admet-1437	311	20	an	an	DET
admet-1437	311	21	amorphous	amorphous	ADJ
admet-1437	311	22	surface	surface	NOUN
admet-1437	311	23	layer	layer	NOUN
admet-1437	311	24	of	of	ADP
admet-1437	311	25	about	about	ADV
admet-1437	311	26	32	32	NUM
admet-1437	311	27	surface	surface	NOUN
admet-1437	311	28	layers	layer	NOUN
admet-1437	311	29	of	of	ADP
admet-1437	311	30	unit	unit	NOUN
admet-1437	311	31	cells	cell	NOUN
admet-1437	311	32	or	or	CCONJ
admet-1437	311	33	a	a	DET
admet-1437	311	34	depth	depth	NOUN
admet-1437	311	35	of	of	ADP
admet-1437	311	36	35	35	NUM
admet-1437	311	37	nm	nm	NOUN
admet-1437	311	38	.	.	PUNCT
admet-1437	312	1	alternatively	alternatively	ADV
admet-1437	312	2	,	,	PUNCT
admet-1437	312	3	it	it	PRON
admet-1437	312	4	can	can	AUX
admet-1437	312	5	be	be	AUX
admet-1437	312	6	hypothesized	hypothesize	VERB
admet-1437	312	7	that	that	SCONJ
admet-1437	312	8	the	the	DET
admet-1437	312	9	x	x	NOUN
admet-1437	312	10	-	-	NOUN
admet-1437	312	11	rays	ray	NOUN
admet-1437	312	12	penetrate	penetrate	VERB
admet-1437	312	13	the	the	DET
admet-1437	312	14	crystal	crystal	NOUN
admet-1437	312	15	as	as	ADP
admet-1437	312	16	a	a	DET
admet-1437	312	17	whole	whole	NOUN
admet-1437	312	18	and	and	CCONJ
admet-1437	312	19	the	the	DET
admet-1437	312	20	resulting	result	VERB
admet-1437	312	21	pattern	pattern	NOUN
admet-1437	312	22	might	might	AUX
admet-1437	312	23	also	also	ADV
admet-1437	312	24	contain	contain	VERB
admet-1437	312	25	contributions	contribution	NOUN
admet-1437	312	26	from	from	ADP
admet-1437	312	27	dislocations	dislocation	NOUN
admet-1437	312	28	and	and	CCONJ
admet-1437	312	29	grain	grain	NOUN
admet-1437	312	30	boundaries	boundary	NOUN
admet-1437	312	31	within	within	ADP
admet-1437	312	32	the	the	DET
admet-1437	312	33	crystals	crystal	NOUN
admet-1437	312	34	,	,	PUNCT
admet-1437	312	35	thereby	thereby	ADV
admet-1437	312	36	possibly	possibly	ADV
admet-1437	312	37	giving	give	VERB
admet-1437	312	38	rise	rise	NOUN
admet-1437	312	39	to	to	ADP
admet-1437	312	40	an	an	DET
admet-1437	312	41	elevated	elevated	ADJ
admet-1437	312	42	estimate	estimate	NOUN
admet-1437	312	43	of	of	ADP
admet-1437	312	44	the	the	DET
admet-1437	312	45	amorphous	amorphous	ADJ
admet-1437	312	46	content	content	NOUN
admet-1437	312	47	admet	admet	PROPN
admet-1437	312	48	&	&	CCONJ
admet-1437	312	49	dmpk	dmpk	PROPN
admet-1437	312	50	10(4	10(4	NUM
admet-1437	312	51	)	)	PUNCT
admet-1437	312	52	(	(	PUNCT
admet-1437	312	53	2022	2022	NUM
admet-1437	312	54	)	)	PUNCT
admet-1437	312	55	253	253	NUM
admet-1437	312	56	-	-	SYM
admet-1437	312	57	287	287	NUM
admet-1437	312	58	modeling	modeling	NOUN
admet-1437	312	59	of	of	ADP
admet-1437	312	60	drug	drug	NOUN
admet-1437	312	61	nanocrystals	nanocrystal	NOUN
admet-1437	312	62	dissolution	dissolution	NOUN
admet-1437	312	63	doi	doi	PROPN
admet-1437	312	64	:	:	PUNCT
admet-1437	312	65	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	312	66	269	269	NUM
admet-1437	312	67	without	without	ADP
admet-1437	312	68	an	an	DET
admet-1437	312	69	increased	increase	VERB
admet-1437	312	70	intrinsic	intrinsic	ADJ
admet-1437	312	71	surface	surface	NOUN
admet-1437	312	72	amorphicity	amorphicity	NOUN
admet-1437	312	73	.	.	PUNCT
admet-1437	313	1	experimental	experimental	ADJ
admet-1437	313	2	results	result	NOUN
admet-1437	313	3	for	for	ADP
admet-1437	313	4	apparent	apparent	ADJ
admet-1437	313	5	solubility	solubility	NOUN
admet-1437	313	6	the	the	DET
admet-1437	313	7	apparent	apparent	ADJ
admet-1437	313	8	solubility	solubility	NOUN
admet-1437	313	9	was	be	AUX
admet-1437	313	10	experimentally	experimentally	ADV
admet-1437	313	11	determined	determine	VERB
admet-1437	313	12	(	(	PUNCT
admet-1437	313	13	sapp	sapp	PROPN
admet-1437	313	14	,	,	PUNCT
admet-1437	313	15	exp	exp	NOUN
admet-1437	313	16	)	)	PUNCT
admet-1437	313	17	for	for	ADP
admet-1437	313	18	all	all	DET
admet-1437	313	19	polydisperse	polydisperse	NOUN
admet-1437	313	20	nanocrystal	nanocrystal	ADJ
admet-1437	313	21	suspensions	suspension	NOUN
admet-1437	313	22	listed	list	VERB
admet-1437	313	23	in	in	ADP
admet-1437	313	24	table	table	NOUN
admet-1437	313	25	2	2	NUM
admet-1437	313	26	in	in	ADP
admet-1437	313	27	ph	ph	ADJ
admet-1437	313	28	3	3	NUM
admet-1437	313	29	citrate	citrate	NOUN
admet-1437	313	30	buffer	buffer	NOUN
admet-1437	313	31	for	for	ADP
admet-1437	313	32	do	do	NOUN
admet-1437	313	33	=	=	SYM
admet-1437	313	34	8.9	8.9	NUM
admet-1437	313	35	.	.	PUNCT
admet-1437	314	1	in	in	ADP
admet-1437	314	2	addition	addition	NOUN
admet-1437	314	3	,	,	PUNCT
admet-1437	314	4	the	the	DET
admet-1437	314	5	apparent	apparent	ADJ
admet-1437	314	6	solubility	solubility	NOUN
admet-1437	314	7	was	be	AUX
admet-1437	314	8	experimentally	experimentally	ADV
admet-1437	314	9	determined	determine	VERB
admet-1437	314	10	for	for	ADP
admet-1437	314	11	a	a	DET
admet-1437	314	12	wide	wide	ADJ
admet-1437	314	13	range	range	NOUN
admet-1437	314	14	of	of	ADP
admet-1437	314	15	do	do	AUX
admet-1437	314	16	values	value	NOUN
admet-1437	314	17	from	from	ADP
admet-1437	314	18	2.7	2.7	NUM
admet-1437	314	19	to	to	ADP
admet-1437	314	20	179	179	NUM
admet-1437	314	21	for	for	ADP
admet-1437	314	22	the	the	DET
admet-1437	314	23	nanocrystal	nanocrystal	ADJ
admet-1437	314	24	suspension	suspension	NOUN
admet-1437	314	25	with	with	ADP
admet-1437	314	26	x50,3	x50,3	PROPN
admet-1437	315	1	=	=	SYM
admet-1437	315	2	111	111	NUM
admet-1437	315	3	nm	nm	NOUN
admet-1437	315	4	in	in	ADP
admet-1437	315	5	ph	ph	ADJ
admet-1437	315	6	3	3	NUM
admet-1437	315	7	citrate	citrate	NOUN
admet-1437	315	8	buffer	buffer	NOUN
admet-1437	315	9	.	.	PUNCT
admet-1437	316	1	table	table	NOUN
admet-1437	316	2	7	7	NUM
admet-1437	316	3	summarizes	summarize	NOUN
admet-1437	316	4	the	the	DET
admet-1437	316	5	results	result	NOUN
admet-1437	316	6	of	of	ADP
admet-1437	316	7	both	both	DET
admet-1437	316	8	sets	set	NOUN
admet-1437	316	9	of	of	ADP
admet-1437	316	10	experiments	experiment	NOUN
admet-1437	316	11	.	.	PUNCT
admet-1437	317	1	the	the	DET
admet-1437	317	2	relative	relative	ADJ
admet-1437	317	3	difference	difference	NOUN
admet-1437	317	4	for	for	ADP
admet-1437	317	5	the	the	DET
admet-1437	317	6	duplicate	duplicate	ADJ
admet-1437	317	7	analysis	analysis	NOUN
admet-1437	317	8	of	of	ADP
admet-1437	317	9	all	all	DET
admet-1437	317	10	samples	sample	NOUN
admet-1437	317	11	was	be	AUX
admet-1437	317	12	identified	identify	VERB
admet-1437	317	13	with	with	ADP
admet-1437	317	14	a	a	DET
admet-1437	317	15	maximum	maximum	NOUN
admet-1437	317	16	of	of	ADP
admet-1437	317	17	4	4	NUM
admet-1437	317	18	%	%	NOUN
admet-1437	317	19	,	,	PUNCT
admet-1437	317	20	highlighting	highlight	VERB
admet-1437	317	21	the	the	DET
admet-1437	317	22	satisfactory	satisfactory	ADJ
admet-1437	317	23	analytical	analytical	ADJ
admet-1437	317	24	precision	precision	NOUN
admet-1437	317	25	of	of	ADP
admet-1437	317	26	the	the	DET
admet-1437	317	27	established	establish	VERB
admet-1437	317	28	apparent	apparent	ADJ
admet-1437	317	29	solubility	solubility	NOUN
admet-1437	317	30	values	value	NOUN
admet-1437	317	31	,	,	PUNCT
admet-1437	317	32	particularly	particularly	ADV
admet-1437	317	33	taking	take	VERB
admet-1437	317	34	into	into	ADP
admet-1437	317	35	consideration	consideration	NOUN
admet-1437	317	36	the	the	DET
admet-1437	317	37	challenging	challenging	ADJ
admet-1437	317	38	nanocrystal	nanocrystal	ADJ
admet-1437	317	39	separation	separation	NOUN
admet-1437	317	40	step	step	NOUN
admet-1437	317	41	.	.	PUNCT
admet-1437	318	1	for	for	ADP
admet-1437	318	2	different	different	ADJ
admet-1437	318	3	particle	particle	NOUN
admet-1437	318	4	size	size	NOUN
admet-1437	318	5	distributions	distribution	NOUN
admet-1437	318	6	with	with	ADP
admet-1437	318	7	a	a	DET
admet-1437	318	8	constant	constant	ADJ
admet-1437	318	9	do	do	NOUN
admet-1437	318	10	,	,	PUNCT
admet-1437	318	11	a	a	DET
admet-1437	318	12	systematic	systematic	ADJ
admet-1437	318	13	increase	increase	NOUN
admet-1437	318	14	of	of	ADP
admet-1437	318	15	the	the	DET
admet-1437	318	16	apparent	apparent	ADJ
admet-1437	318	17	solubility	solubility	NOUN
admet-1437	318	18	with	with	ADP
admet-1437	318	19	decreasing	decrease	VERB
admet-1437	318	20	median	median	ADJ
admet-1437	318	21	nanocrystal	nanocrystal	ADJ
admet-1437	318	22	particle	particle	NOUN
admet-1437	318	23	size	size	NOUN
admet-1437	318	24	x50,3	x50,3	PROPN
admet-1437	318	25	is	be	AUX
admet-1437	318	26	observed	observe	VERB
admet-1437	318	27	,	,	PUNCT
admet-1437	318	28	as	as	SCONJ
admet-1437	318	29	described	describe	VERB
admet-1437	318	30	by	by	ADP
admet-1437	318	31	the	the	DET
admet-1437	318	32	ostwald	ostwald	NOUN
admet-1437	318	33	-	-	PUNCT
admet-1437	318	34	freundlich	freundlich	ADJ
admet-1437	318	35	equation	equation	NOUN
admet-1437	318	36	.	.	PUNCT
admet-1437	319	1	the	the	DET
admet-1437	319	2	apparent	apparent	ADJ
admet-1437	319	3	solubility	solubility	NOUN
admet-1437	319	4	increases	increase	VERB
admet-1437	319	5	from	from	ADP
admet-1437	319	6	the	the	DET
admet-1437	319	7	initial	initial	ADJ
admet-1437	319	8	coarse	coarse	NOUN
admet-1437	319	9	crystal	crystal	NOUN
admet-1437	319	10	suspension	suspension	NOUN
admet-1437	319	11	to	to	ADP
admet-1437	319	12	the	the	DET
admet-1437	319	13	finest	fine	ADJ
admet-1437	319	14	nanocrystal	nanocrystal	ADJ
admet-1437	319	15	particle	particle	NOUN
admet-1437	319	16	size	size	NOUN
admet-1437	319	17	distribution	distribution	NOUN
admet-1437	319	18	by	by	ADP
admet-1437	319	19	almost	almost	ADV
admet-1437	319	20	a	a	PRON
admet-1437	319	21	factor	factor	NOUN
admet-1437	319	22	of	of	ADP
admet-1437	319	23	2	2	NUM
admet-1437	319	24	.	.	PUNCT
admet-1437	319	25	as	as	ADP
admet-1437	319	26	a	a	DET
admet-1437	319	27	general	general	ADJ
admet-1437	319	28	point	point	NOUN
admet-1437	319	29	,	,	PUNCT
admet-1437	319	30	the	the	DET
admet-1437	319	31	determined	determined	ADJ
admet-1437	319	32	increase	increase	NOUN
admet-1437	319	33	of	of	ADP
admet-1437	319	34	the	the	DET
admet-1437	319	35	apparent	apparent	ADJ
admet-1437	319	36	solubility	solubility	NOUN
admet-1437	319	37	compared	compare	VERB
admet-1437	319	38	to	to	ADP
admet-1437	319	39	the	the	DET
admet-1437	319	40	thermodynamic	thermodynamic	ADJ
admet-1437	319	41	solubility	solubility	NOUN
admet-1437	319	42	is	be	AUX
admet-1437	319	43	a	a	DET
admet-1437	319	44	matter	matter	NOUN
admet-1437	319	45	of	of	ADP
admet-1437	319	46	true	true	ADJ
admet-1437	319	47	supersaturation	supersaturation	NOUN
admet-1437	319	48	for	for	ADP
admet-1437	319	49	this	this	DET
admet-1437	319	50	specific	specific	ADJ
admet-1437	319	51	drugstabilizer	drugstabilizer	NOUN
admet-1437	319	52	system	system	NOUN
admet-1437	319	53	.	.	PUNCT
admet-1437	320	1	the	the	DET
admet-1437	320	2	increase	increase	NOUN
admet-1437	320	3	in	in	ADP
admet-1437	320	4	apparent	apparent	ADJ
admet-1437	320	5	solubility	solubility	NOUN
admet-1437	320	6	by	by	ADP
admet-1437	320	7	almost	almost	ADV
admet-1437	320	8	a	a	PRON
admet-1437	320	9	factor	factor	NOUN
admet-1437	320	10	of	of	ADP
admet-1437	320	11	2	2	NUM
admet-1437	320	12	is	be	AUX
admet-1437	320	13	significantly	significantly	ADV
admet-1437	320	14	higher	high	ADJ
admet-1437	320	15	compared	compare	VERB
admet-1437	320	16	to	to	ADP
admet-1437	320	17	so	so	ADV
admet-1437	320	18	far	far	ADV
admet-1437	320	19	reported	report	VERB
admet-1437	320	20	values	value	NOUN
admet-1437	320	21	[	[	X
admet-1437	320	22	8,43	8,43	NUM
admet-1437	320	23	-	-	SYM
admet-1437	320	24	46	46	NUM
admet-1437	320	25	]	]	PUNCT
admet-1437	320	26	.	.	PUNCT
admet-1437	321	1	this	this	PRON
admet-1437	321	2	is	be	AUX
admet-1437	321	3	reasonable	reasonable	ADJ
admet-1437	321	4	due	due	ADP
admet-1437	321	5	to	to	ADP
admet-1437	321	6	the	the	DET
admet-1437	321	7	significantly	significantly	ADV
admet-1437	321	8	finer	fine	ADJ
admet-1437	321	9	drug	drug	NOUN
admet-1437	321	10	particle	particle	NOUN
admet-1437	321	11	size	size	NOUN
admet-1437	321	12	distributions	distribution	NOUN
admet-1437	321	13	evaluated	evaluate	VERB
admet-1437	321	14	in	in	ADP
admet-1437	321	15	this	this	DET
admet-1437	321	16	study	study	NOUN
admet-1437	321	17	.	.	PUNCT
admet-1437	322	1	it	it	PRON
admet-1437	322	2	can	can	AUX
admet-1437	322	3	be	be	AUX
admet-1437	322	4	noted	note	VERB
admet-1437	322	5	that	that	SCONJ
admet-1437	322	6	the	the	DET
admet-1437	322	7	increase	increase	NOUN
admet-1437	322	8	in	in	ADP
admet-1437	322	9	apparent	apparent	ADJ
admet-1437	322	10	solubility	solubility	NOUN
admet-1437	322	11	with	with	ADP
admet-1437	322	12	decreasing	decrease	VERB
admet-1437	322	13	particle	particle	NOUN
admet-1437	322	14	size	size	NOUN
admet-1437	322	15	becomes	become	VERB
admet-1437	322	16	significant	significant	ADJ
admet-1437	322	17	for	for	ADP
admet-1437	322	18	the	the	DET
admet-1437	322	19	studied	study	VERB
admet-1437	322	20	drug	drug	NOUN
admet-1437	322	21	compound	compound	NOUN
admet-1437	322	22	only	only	ADV
admet-1437	322	23	for	for	ADP
admet-1437	322	24	x50,3	x50,3	PROPN
admet-1437	323	1	<	<	X
admet-1437	323	2	<	<	X
admet-1437	323	3	1	1	NUM
admet-1437	323	4	µm	µm	NOUN
admet-1437	323	5	.	.	PUNCT
admet-1437	324	1	the	the	DET
admet-1437	324	2	characteristic	characteristic	ADJ
admet-1437	324	3	particle	particle	NOUN
admet-1437	324	4	size	size	NOUN
admet-1437	324	5	where	where	SCONJ
admet-1437	324	6	the	the	DET
admet-1437	324	7	increase	increase	NOUN
admet-1437	324	8	of	of	ADP
admet-1437	324	9	apparent	apparent	ADJ
admet-1437	324	10	solubility	solubility	NOUN
admet-1437	324	11	due	due	ADP
admet-1437	324	12	to	to	ADP
admet-1437	324	13	the	the	DET
admet-1437	324	14	decrease	decrease	NOUN
admet-1437	324	15	of	of	ADP
admet-1437	324	16	particle	particle	NOUN
admet-1437	324	17	size	size	NOUN
admet-1437	324	18	becomes	become	VERB
admet-1437	324	19	significant	significant	ADJ
admet-1437	324	20	depends	depend	VERB
admet-1437	324	21	on	on	ADP
admet-1437	324	22	the	the	DET
admet-1437	324	23	specific	specific	ADJ
admet-1437	324	24	drug	drug	NOUN
admet-1437	324	25	-	-	PUNCT
admet-1437	324	26	stabilizer	stabilizer	NOUN
admet-1437	324	27	system	system	NOUN
admet-1437	324	28	.	.	PUNCT
admet-1437	325	1	this	this	PRON
admet-1437	325	2	includes	include	VERB
admet-1437	325	3	the	the	DET
admet-1437	325	4	finest	fine	ADJ
admet-1437	325	5	particle	particle	NOUN
admet-1437	325	6	size	size	NOUN
admet-1437	325	7	and	and	CCONJ
admet-1437	325	8	the	the	DET
admet-1437	325	9	related	relate	VERB
admet-1437	325	10	amount	amount	NOUN
admet-1437	325	11	of	of	ADP
admet-1437	325	12	fines	fine	NOUN
admet-1437	325	13	of	of	ADP
admet-1437	325	14	the	the	DET
admet-1437	325	15	drug	drug	NOUN
admet-1437	325	16	particle	particle	NOUN
admet-1437	325	17	size	size	NOUN
admet-1437	325	18	distribution	distribution	NOUN
admet-1437	325	19	,	,	PUNCT
admet-1437	325	20	the	the	DET
admet-1437	325	21	interfacial	interfacial	ADJ
admet-1437	325	22	energy	energy	NOUN
admet-1437	325	23	between	between	ADP
admet-1437	325	24	solid	solid	ADJ
admet-1437	325	25	and	and	CCONJ
admet-1437	325	26	liquid	liquid	ADJ
admet-1437	325	27	σsl	σsl	ADV
admet-1437	325	28	,	,	PUNCT
admet-1437	325	29	the	the	DET
admet-1437	325	30	drug	drug	NOUN
admet-1437	325	31	molar	molar	PROPN
admet-1437	325	32	volume	volume	PROPN
admet-1437	325	33	vm	vm	PROPN
admet-1437	325	34	,	,	PUNCT
admet-1437	325	35	and	and	CCONJ
admet-1437	325	36	the	the	DET
admet-1437	325	37	stability	stability	NOUN
admet-1437	325	38	of	of	ADP
admet-1437	325	39	the	the	DET
admet-1437	325	40	supersaturation	supersaturation	NOUN
admet-1437	325	41	regarding	regard	VERB
admet-1437	325	42	precipitation	precipitation	NOUN
admet-1437	325	43	and	and	CCONJ
admet-1437	325	44	ostwald	ostwald	NOUN
admet-1437	325	45	ripening	ripening	NOUN
admet-1437	325	46	.	.	PUNCT
admet-1437	326	1	the	the	DET
admet-1437	326	2	definition	definition	NOUN
admet-1437	326	3	of	of	ADP
admet-1437	326	4	a	a	DET
admet-1437	326	5	general	general	ADJ
admet-1437	326	6	particle	particle	NOUN
admet-1437	326	7	size	size	NOUN
admet-1437	326	8	threshold	threshold	NOUN
admet-1437	326	9	,	,	PUNCT
admet-1437	326	10	below	below	ADP
admet-1437	326	11	which	which	PRON
admet-1437	326	12	solubility	solubility	NOUN
admet-1437	326	13	increases	increase	VERB
admet-1437	326	14	due	due	ADJ
admet-1437	326	15	to	to	ADP
admet-1437	326	16	decreasing	decrease	VERB
admet-1437	326	17	particle	particle	NOUN
admet-1437	326	18	size	size	NOUN
admet-1437	326	19	becomes	become	VERB
admet-1437	326	20	significant	significant	ADJ
admet-1437	326	21	,	,	PUNCT
admet-1437	326	22	is	be	AUX
admet-1437	326	23	therefore	therefore	ADV
admet-1437	326	24	not	not	PART
admet-1437	326	25	possible	possible	ADJ
admet-1437	326	26	.	.	PUNCT
admet-1437	327	1	instead	instead	ADV
admet-1437	327	2	,	,	PUNCT
admet-1437	327	3	this	this	DET
admet-1437	327	4	question	question	NOUN
admet-1437	327	5	must	must	AUX
admet-1437	327	6	be	be	AUX
admet-1437	327	7	evaluated	evaluate	VERB
admet-1437	327	8	for	for	ADP
admet-1437	327	9	each	each	DET
admet-1437	327	10	specific	specific	ADJ
admet-1437	327	11	drugstabilizer	drugstabilizer	NOUN
admet-1437	327	12	system	system	NOUN
admet-1437	327	13	.	.	PUNCT
admet-1437	328	1	interestingly	interestingly	ADV
admet-1437	328	2	,	,	PUNCT
admet-1437	328	3	a	a	DET
admet-1437	328	4	dependence	dependence	NOUN
admet-1437	328	5	of	of	ADP
admet-1437	328	6	the	the	DET
admet-1437	328	7	apparent	apparent	ADJ
admet-1437	328	8	solubility	solubility	NOUN
admet-1437	328	9	on	on	ADP
admet-1437	328	10	do	do	AUX
admet-1437	328	11	is	be	AUX
admet-1437	328	12	identified	identify	VERB
admet-1437	328	13	for	for	ADP
admet-1437	328	14	the	the	DET
admet-1437	328	15	same	same	ADJ
admet-1437	328	16	nanocrystal	nanocrystal	ADJ
admet-1437	328	17	particle	particle	NOUN
admet-1437	328	18	size	size	NOUN
admet-1437	328	19	distribution	distribution	NOUN
admet-1437	328	20	,	,	PUNCT
admet-1437	328	21	see	see	VERB
admet-1437	328	22	experiments	experiment	NOUN
admet-1437	328	23	no	no	INTJ
admet-1437	328	24	.	.	NOUN
admet-1437	328	25	9	9	NUM
admet-1437	328	26	to	to	PART
admet-1437	328	27	15	15	NUM
admet-1437	328	28	in	in	ADP
admet-1437	328	29	table	table	NOUN
admet-1437	328	30	7	7	NUM
admet-1437	328	31	.	.	PUNCT
admet-1437	329	1	while	while	SCONJ
admet-1437	329	2	the	the	DET
admet-1437	329	3	apparent	apparent	ADJ
admet-1437	329	4	solubility	solubility	NOUN
admet-1437	329	5	increases	increase	VERB
admet-1437	329	6	notably	notably	ADV
admet-1437	329	7	with	with	ADP
admet-1437	329	8	increasing	increase	VERB
admet-1437	329	9	do	do	AUX
admet-1437	329	10	in	in	ADP
admet-1437	329	11	the	the	DET
admet-1437	329	12	lower	low	ADJ
admet-1437	329	13	do	do	AUX
admet-1437	329	14	range	range	VERB
admet-1437	329	15	up	up	ADP
admet-1437	329	16	to	to	ADP
admet-1437	329	17	a	a	DET
admet-1437	329	18	value	value	NOUN
admet-1437	329	19	of	of	ADP
admet-1437	329	20	do	do	NOUN
admet-1437	329	21	=	=	SYM
admet-1437	329	22	18	18	NUM
admet-1437	329	23	,	,	PUNCT
admet-1437	329	24	a	a	DET
admet-1437	329	25	plateauing	plateauing	NOUN
admet-1437	329	26	is	be	AUX
admet-1437	329	27	observed	observe	VERB
admet-1437	329	28	for	for	ADP
admet-1437	329	29	the	the	DET
admet-1437	329	30	higher	high	ADJ
admet-1437	329	31	do	do	AUX
admet-1437	329	32	range	range	NOUN
admet-1437	329	33	.	.	PUNCT
admet-1437	330	1	the	the	DET
admet-1437	330	2	ostwald	ostwald	NOUN
admet-1437	330	3	-	-	PUNCT
admet-1437	330	4	freundlich	freundlich	ADJ
admet-1437	330	5	equation	equation	NOUN
admet-1437	330	6	considering	consider	VERB
admet-1437	330	7	x50,3	x50,3	PROPN
admet-1437	330	8	alone	alone	ADV
admet-1437	330	9	is	be	AUX
admet-1437	330	10	not	not	PART
admet-1437	330	11	sufficient	sufficient	ADJ
admet-1437	330	12	for	for	ADP
admet-1437	330	13	the	the	DET
admet-1437	330	14	explanation	explanation	NOUN
admet-1437	330	15	of	of	ADP
admet-1437	330	16	this	this	DET
admet-1437	330	17	behavior	behavior	NOUN
admet-1437	330	18	,	,	PUNCT
admet-1437	330	19	as	as	ADP
admet-1437	330	20	the	the	DET
admet-1437	330	21	entire	entire	ADJ
admet-1437	330	22	particle	particle	NOUN
admet-1437	330	23	size	size	NOUN
admet-1437	330	24	distribution	distribution	NOUN
admet-1437	330	25	and	and	CCONJ
admet-1437	330	26	its	its	PRON
admet-1437	330	27	evolution	evolution	NOUN
admet-1437	330	28	during	during	ADP
admet-1437	330	29	dissolution	dissolution	NOUN
admet-1437	330	30	need	need	NOUN
admet-1437	330	31	to	to	PART
admet-1437	330	32	be	be	AUX
admet-1437	330	33	considered	consider	VERB
admet-1437	330	34	.	.	PUNCT
admet-1437	331	1	while	while	SCONJ
admet-1437	331	2	for	for	ADP
admet-1437	331	3	systems	system	NOUN
admet-1437	331	4	with	with	ADP
admet-1437	331	5	x	x	SYM
admet-1437	331	6	≫	≫	PROPN
admet-1437	331	7	1	1	NUM
admet-1437	331	8	µm	µm	NOUN
admet-1437	331	9	,	,	PUNCT
admet-1437	331	10	an	an	DET
admet-1437	331	11	increase	increase	NOUN
admet-1437	331	12	in	in	ADP
admet-1437	331	13	do	do	NOUN
admet-1437	331	14	only	only	ADV
admet-1437	331	15	results	result	NOUN
admet-1437	331	16	in	in	ADP
admet-1437	331	17	an	an	DET
admet-1437	331	18	increase	increase	NOUN
admet-1437	331	19	of	of	ADP
admet-1437	331	20	available	available	ADJ
admet-1437	331	21	liquid	liquid	NOUN
admet-1437	331	22	-	-	PUNCT
admet-1437	331	23	solid	solid	ADJ
admet-1437	331	24	surface	surface	NOUN
admet-1437	331	25	area	area	NOUN
admet-1437	331	26	for	for	ADP
admet-1437	331	27	dissolution	dissolution	NOUN
admet-1437	331	28	and	and	CCONJ
admet-1437	331	29	thereby	thereby	ADV
admet-1437	331	30	faster	fast	ADV
admet-1437	331	31	dissolution	dissolution	ADJ
admet-1437	331	32	kinetics	kinetic	NOUN
admet-1437	331	33	,	,	PUNCT
admet-1437	331	34	the	the	DET
admet-1437	331	35	implications	implication	NOUN
admet-1437	331	36	for	for	ADP
admet-1437	331	37	systems	system	NOUN
admet-1437	331	38	with	with	ADP
admet-1437	331	39	x	x	SYM
admet-1437	331	40	≪	≪	ADJ
admet-1437	331	41	1	1	NUM
admet-1437	331	42	µm	µm	NUM
admet-1437	331	43	are	be	AUX
admet-1437	331	44	more	more	ADV
admet-1437	331	45	complex	complex	ADJ
admet-1437	331	46	,	,	PUNCT
admet-1437	331	47	finally	finally	ADV
admet-1437	331	48	impacting	impact	VERB
admet-1437	331	49	not	not	PART
admet-1437	331	50	only	only	ADV
admet-1437	331	51	the	the	DET
admet-1437	331	52	available	available	ADJ
admet-1437	331	53	liquid	liquid	NOUN
admet-1437	331	54	-	-	PUNCT
admet-1437	331	55	solid	solid	ADJ
admet-1437	331	56	surface	surface	NOUN
admet-1437	331	57	area	area	NOUN
admet-1437	331	58	but	but	CCONJ
admet-1437	331	59	also	also	ADV
admet-1437	331	60	the	the	DET
admet-1437	331	61	shape	shape	NOUN
admet-1437	331	62	of	of	ADP
admet-1437	331	63	the	the	DET
admet-1437	331	64	particle	particle	NOUN
admet-1437	331	65	size	size	NOUN
admet-1437	331	66	distribution	distribution	NOUN
admet-1437	331	67	at	at	ADP
admet-1437	331	68	the	the	DET
admet-1437	331	69	end	end	NOUN
admet-1437	331	70	of	of	ADP
admet-1437	331	71	the	the	DET
admet-1437	331	72	dissolution	dissolution	NOUN
admet-1437	331	73	process	process	NOUN
admet-1437	331	74	and	and	CCONJ
admet-1437	331	75	thereby	thereby	ADV
admet-1437	331	76	the	the	DET
admet-1437	331	77	resulting	result	VERB
admet-1437	331	78	apparent	apparent	ADJ
admet-1437	331	79	solubility	solubility	NOUN
admet-1437	331	80	.	.	PUNCT
admet-1437	332	1	a	a	DET
admet-1437	332	2	simplified	simplified	ADJ
admet-1437	332	3	thought	think	VERB
admet-1437	332	4	experiment	experiment	NOUN
admet-1437	332	5	might	might	AUX
admet-1437	332	6	facilitate	facilitate	VERB
admet-1437	332	7	the	the	DET
admet-1437	332	8	understanding	understanding	NOUN
admet-1437	332	9	of	of	ADP
admet-1437	332	10	the	the	DET
admet-1437	332	11	observed	observed	ADJ
admet-1437	332	12	behavior	behavior	NOUN
admet-1437	332	13	.	.	PUNCT
admet-1437	333	1	for	for	ADP
admet-1437	333	2	two	two	NUM
admet-1437	333	3	theoretical	theoretical	ADJ
admet-1437	333	4	scenarios	scenario	NOUN
admet-1437	333	5	with	with	ADP
admet-1437	333	6	do	do	AUX
admet-1437	333	7	values	value	NOUN
admet-1437	333	8	of	of	ADP
admet-1437	333	9	3	3	NUM
admet-1437	333	10	and	and	CCONJ
admet-1437	333	11	20	20	NUM
admet-1437	333	12	,	,	PUNCT
admet-1437	333	13	the	the	DET
admet-1437	333	14	dissolved	dissolve	VERB
admet-1437	333	15	solids	solid	NOUN
admet-1437	333	16	at	at	ADP
admet-1437	333	17	equilibrium	equilibrium	NOUN
admet-1437	333	18	will	will	AUX
admet-1437	333	19	be	be	AUX
admet-1437	333	20	roughly	roughly	ADV
admet-1437	333	21	1/3	1/3	NUM
admet-1437	333	22	and	and	CCONJ
admet-1437	333	23	1/20	1/20	NUM
admet-1437	333	24	,	,	PUNCT
admet-1437	333	25	respectively	respectively	ADV
admet-1437	333	26	.	.	PUNCT
admet-1437	334	1	assuming	assume	VERB
admet-1437	334	2	that	that	SCONJ
admet-1437	334	3	the	the	DET
admet-1437	334	4	small	small	ADJ
admet-1437	334	5	particles	particle	NOUN
admet-1437	334	6	dissolve	dissolve	VERB
admet-1437	334	7	first	first	ADV
admet-1437	334	8	due	due	ADP
admet-1437	334	9	to	to	ADP
admet-1437	334	10	their	their	PRON
admet-1437	334	11	size	size	NOUN
admet-1437	334	12	and	and	CCONJ
admet-1437	334	13	increased	increase	VERB
admet-1437	334	14	apparent	apparent	ADJ
admet-1437	334	15	solubility	solubility	NOUN
admet-1437	334	16	,	,	PUNCT
admet-1437	334	17	the	the	DET
admet-1437	334	18	smallest	small	ADJ
admet-1437	334	19	remaining	remain	VERB
admet-1437	334	20	particle	particle	NOUN
admet-1437	334	21	after	after	SCONJ
admet-1437	334	22	dissolution	dissolution	NOUN
admet-1437	334	23	would	would	AUX
admet-1437	334	24	correspond	correspond	VERB
admet-1437	334	25	to	to	ADP
admet-1437	334	26	x33,3	x33,3	PROPN
admet-1437	334	27	and	and	CCONJ
admet-1437	334	28	x5,3	x5,3	PROPN
admet-1437	334	29	,	,	PUNCT
admet-1437	334	30	respectively	respectively	ADV
admet-1437	334	31	,	,	PUNCT
admet-1437	334	32	neglecting	neglect	VERB
admet-1437	334	33	,	,	PUNCT
admet-1437	334	34	for	for	ADP
admet-1437	334	35	now	now	ADV
admet-1437	334	36	,	,	PUNCT
admet-1437	334	37	the	the	DET
admet-1437	334	38	size	size	NOUN
admet-1437	334	39	reduction	reduction	NOUN
admet-1437	334	40	of	of	ADP
admet-1437	334	41	those	those	DET
admet-1437	334	42	particles	particle	NOUN
admet-1437	334	43	during	during	ADP
admet-1437	334	44	the	the	DET
admet-1437	334	45	dissolution	dissolution	NOUN
admet-1437	334	46	process	process	NOUN
admet-1437	334	47	.	.	PUNCT
admet-1437	335	1	since	since	SCONJ
admet-1437	335	2	x5,3	x5,3	PROPN
admet-1437	335	3	<	<	X
admet-1437	335	4	x33,3	x33,3	PROPN
admet-1437	335	5	,	,	PUNCT
admet-1437	335	6	the	the	DET
admet-1437	335	7	measured	measured	ADJ
admet-1437	335	8	apparent	apparent	ADJ
admet-1437	335	9	solubility	solubility	NOUN
admet-1437	335	10	for	for	ADP
admet-1437	335	11	the	the	DET
admet-1437	335	12	scenario	scenario	NOUN
admet-1437	335	13	with	with	ADP
admet-1437	335	14	do	do	AUX
admet-1437	335	15	=	=	SYM
admet-1437	335	16	20	20	NUM
admet-1437	335	17	is	be	AUX
admet-1437	335	18	expected	expect	VERB
admet-1437	335	19	to	to	PART
admet-1437	335	20	be	be	AUX
admet-1437	335	21	higher	high	ADJ
admet-1437	335	22	compared	compare	VERB
admet-1437	335	23	to	to	PART
admet-1437	335	24	do	do	VERB
admet-1437	335	25	=	=	SYM
admet-1437	335	26	3	3	X
admet-1437	335	27	.	.	X
admet-1437	335	28	other	other	ADJ
admet-1437	335	29	studies	study	NOUN
admet-1437	335	30	have	have	AUX
admet-1437	335	31	also	also	ADV
admet-1437	335	32	varied	varied	ADJ
admet-1437	335	33	do	do	VERB
admet-1437	335	34	in	in	ADP
admet-1437	335	35	different	different	ADJ
admet-1437	335	36	scenarios	scenario	NOUN
admet-1437	335	37	[	[	X
admet-1437	335	38	31,54	31,54	NUM
admet-1437	335	39	]	]	X
admet-1437	335	40	.	.	PUNCT
admet-1437	336	1	however	however	ADV
admet-1437	336	2	,	,	PUNCT
admet-1437	336	3	the	the	DET
admet-1437	336	4	complex	complex	ADJ
admet-1437	336	5	implications	implication	NOUN
admet-1437	336	6	of	of	ADP
admet-1437	336	7	this	this	DET
admet-1437	336	8	parameter	parameter	NOUN
admet-1437	336	9	were	be	AUX
admet-1437	336	10	not	not	PART
admet-1437	336	11	always	always	ADV
admet-1437	336	12	fully	fully	ADV
admet-1437	336	13	considered	consider	VERB
admet-1437	336	14	.	.	PUNCT
admet-1437	337	1	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	X
admet-1437	337	2	bonhoeffer	bonhoeffer	PROPN
admet-1437	337	3	et	et	PROPN
admet-1437	337	4	al	al	PROPN
admet-1437	337	5	.	.	PROPN
admet-1437	337	6	admet	admet	PROPN
admet-1437	337	7	&	&	CCONJ
admet-1437	337	8	dmpk	dmpk	PROPN
admet-1437	337	9	10(4	10(4	NUM
admet-1437	337	10	)	)	PUNCT
admet-1437	337	11	(	(	PUNCT
admet-1437	337	12	2022	2022	NUM
admet-1437	337	13	)	)	PUNCT
admet-1437	337	14	253	253	NUM
admet-1437	337	15	-	-	SYM
admet-1437	337	16	287	287	NUM
admet-1437	337	17	270	270	NUM
admet-1437	337	18	table	table	NOUN
admet-1437	337	19	7	7	NUM
admet-1437	337	20	.	.	PUNCT
admet-1437	337	21	experimental	experimental	ADJ
admet-1437	337	22	results	result	NOUN
admet-1437	337	23	for	for	ADP
admet-1437	337	24	apparent	apparent	ADJ
admet-1437	337	25	solubility	solubility	NOUN
admet-1437	337	26	(	(	PUNCT
admet-1437	337	27	sapp	sapp	PROPN
admet-1437	337	28	,	,	PUNCT
admet-1437	337	29	exp	exp	NOUN
admet-1437	337	30	)	)	PUNCT
admet-1437	337	31	for	for	ADP
admet-1437	337	32	polydisperse	polydisperse	NOUN
admet-1437	337	33	particle	particle	NOUN
admet-1437	337	34	size	size	NOUN
admet-1437	337	35	distributions	distribution	NOUN
admet-1437	337	36	according	accord	VERB
admet-1437	337	37	to	to	ADP
admet-1437	337	38	table	table	NOUN
admet-1437	337	39	2	2	NUM
admet-1437	337	40	as	as	SCONJ
admet-1437	337	41	determined	determine	VERB
admet-1437	337	42	by	by	ADP
admet-1437	337	43	high	high	ADJ
admet-1437	337	44	-	-	PUNCT
admet-1437	337	45	pressure	pressure	NOUN
admet-1437	337	46	liquid	liquid	ADJ
admet-1437	337	47	chromatography	chromatography	NOUN
admet-1437	337	48	(	(	PUNCT
admet-1437	337	49	hplc	hplc	PROPN
admet-1437	337	50	)	)	PUNCT
admet-1437	337	51	in	in	ADP
admet-1437	337	52	dissolution	dissolution	ADJ
admet-1437	337	53	media	medium	NOUN
admet-1437	337	54	of	of	ADP
admet-1437	337	55	ph	ph	PROPN
admet-1437	337	56	3	3	NUM
admet-1437	337	57	at	at	ADP
admet-1437	337	58	22	22	NUM
admet-1437	337	59	°	°	NOUN
admet-1437	337	60	c	c	NOUN
admet-1437	337	61	.	.	PUNCT
admet-1437	338	1	experiment	experiment	NOUN
admet-1437	338	2	no	no	PROPN
admet-1437	338	3	.	.	PUNCT
admet-1437	339	1	solids	solid	NOUN
admet-1437	339	2	amount	amount	VERB
admet-1437	339	3	m	m	PROPN
admet-1437	339	4	/	/	SYM
admet-1437	339	5	g	g	PROPN
admet-1437	339	6	dose	dose	NOUN
admet-1437	339	7	number	number	NOUN
admet-1437	339	8	do	do	AUX
admet-1437	339	9	/	/	SYM
admet-1437	339	10	particle	particle	NOUN
admet-1437	339	11	size	size	NOUN
admet-1437	339	12	x50,3	x50,3	PROPN
admet-1437	339	13	/	/	SYM
admet-1437	339	14	nm	nm	PROPN
admet-1437	339	15	solubility	solubility	NOUN
admet-1437	339	16	in	in	ADP
admet-1437	339	17	ph	ph	PROPN
admet-1437	339	18	3	3	NUM
admet-1437	339	19	sapp	sapp	VERB
admet-1437	339	20	,	,	PUNCT
admet-1437	339	21	exp	exp	NOUN
admet-1437	339	22	/	/	SYM
admet-1437	339	23	mg	mg	PROPN
admet-1437	339	24	/	/	SYM
admet-1437	339	25	l	l	NOUN
admet-1437	339	26	1	1	NUM
admet-1437	339	27	0.25	0.25	NUM
admet-1437	339	28	8.9	8.9	NUM
admet-1437	339	29	2443	2443	NUM
admet-1437	339	30	30.3	30.3	NUM
admet-1437	339	31	2	2	NUM
admet-1437	339	32	0.25	0.25	NUM
admet-1437	339	33	8.9	8.9	NUM
admet-1437	339	34	261	261	NUM
admet-1437	339	35	34.9	34.9	NUM
admet-1437	339	36	3	3	NUM
admet-1437	339	37	0.25	0.25	NUM
admet-1437	339	38	8.9	8.9	NUM
admet-1437	339	39	201	201	NUM
admet-1437	339	40	39.8	39.8	NUM
admet-1437	339	41	4	4	NUM
admet-1437	339	42	0.25	0.25	NUM
admet-1437	339	43	8.9	8.9	NUM
admet-1437	339	44	140	140	NUM
admet-1437	339	45	48.1	48.1	NUM
admet-1437	339	46	5	5	NUM
admet-1437	339	47	0.25	0.25	NUM
admet-1437	339	48	8.9	8.9	NUM
admet-1437	339	49	111	111	NUM
admet-1437	339	50	49.9	49.9	NUM
admet-1437	339	51	6	6	NUM
admet-1437	339	52	0.25	0.25	NUM
admet-1437	339	53	8.9	8.9	NUM
admet-1437	339	54	93	93	NUM
admet-1437	339	55	53.9	53.9	NUM
admet-1437	339	56	7	7	NUM
admet-1437	339	57	0.25	0.25	NUM
admet-1437	339	58	8.9	8.9	NUM
admet-1437	339	59	90	90	NUM
admet-1437	339	60	52.6	52.6	NUM
admet-1437	339	61	8	8	NUM
admet-1437	339	62	0.25	0.25	NUM
admet-1437	339	63	8.9	8.9	NUM
admet-1437	339	64	79	79	NUM
admet-1437	339	65	55.7	55.7	NUM
admet-1437	339	66	9	9	NUM
admet-1437	339	67	0.075	0.075	NUM
admet-1437	339	68	2.7	2.7	NUM
admet-1437	339	69	111	111	NUM
admet-1437	339	70	41.6	41.6	NUM
admet-1437	339	71	10	10	NUM
admet-1437	339	72	0.125	0.125	NUM
admet-1437	339	73	4.5	4.5	NUM
admet-1437	339	74	111	111	NUM
admet-1437	339	75	47.2	47.2	NUM
admet-1437	339	76	11	11	NUM
admet-1437	339	77	0.25	0.25	NUM
admet-1437	339	78	8.9	8.9	NUM
admet-1437	339	79	111	111	NUM
admet-1437	339	80	49.9	49.9	NUM
admet-1437	339	81	12	12	NUM
admet-1437	339	82	0.5	0.5	NUM
admet-1437	339	83	18	18	NUM
admet-1437	339	84	111	111	NUM
admet-1437	339	85	51.3	51.3	NUM
admet-1437	339	86	13	13	NUM
admet-1437	339	87	1.25	1.25	NUM
admet-1437	339	88	45	45	NUM
admet-1437	339	89	111	111	NUM
admet-1437	339	90	51.9	51.9	NUM
admet-1437	339	91	14	14	NUM
admet-1437	339	92	2.5	2.5	NUM
admet-1437	339	93	89	89	NUM
admet-1437	339	94	111	111	NUM
admet-1437	339	95	52.1	52.1	NUM
admet-1437	339	96	15	15	NUM
admet-1437	339	97	5	5	NUM
admet-1437	339	98	179	179	NUM
admet-1437	339	99	111	111	NUM
admet-1437	339	100	52.5	52.5	NUM
admet-1437	339	101	numerical	numerical	ADJ
admet-1437	339	102	model	model	NOUN
admet-1437	339	103	the	the	DET
admet-1437	339	104	interfacial	interfacial	ADJ
admet-1437	339	105	energy	energy	NOUN
admet-1437	339	106	between	between	ADP
admet-1437	339	107	solid	solid	ADJ
admet-1437	339	108	and	and	CCONJ
admet-1437	339	109	liquid	liquid	NOUN
admet-1437	339	110	remains	remain	VERB
admet-1437	339	111	an	an	DET
admet-1437	339	112	unknown	unknown	ADJ
admet-1437	339	113	parameter	parameter	NOUN
admet-1437	339	114	since	since	SCONJ
admet-1437	339	115	there	there	PRON
admet-1437	339	116	are	be	VERB
admet-1437	339	117	no	no	DET
admet-1437	339	118	analytical	analytical	ADJ
admet-1437	339	119	techniques	technique	NOUN
admet-1437	339	120	available	available	ADJ
admet-1437	339	121	to	to	PART
admet-1437	339	122	directly	directly	ADV
admet-1437	339	123	characterize	characterize	VERB
admet-1437	339	124	the	the	DET
admet-1437	339	125	interfacial	interfacial	ADJ
admet-1437	339	126	energy	energy	NOUN
admet-1437	339	127	between	between	ADP
admet-1437	339	128	drug	drug	NOUN
admet-1437	339	129	nanocrystals	nanocrystal	NOUN
admet-1437	339	130	in	in	ADP
admet-1437	339	131	suspension	suspension	NOUN
admet-1437	339	132	that	that	PRON
admet-1437	339	133	contains	contain	VERB
admet-1437	339	134	stabilizers	stabilizer	NOUN
admet-1437	339	135	absorbed	absorb	VERB
admet-1437	339	136	on	on	ADP
admet-1437	339	137	its	its	PRON
admet-1437	339	138	surface	surface	NOUN
admet-1437	339	139	and	and	CCONJ
admet-1437	339	140	the	the	DET
admet-1437	339	141	aqueous	aqueous	ADJ
admet-1437	339	142	liquid	liquid	ADJ
admet-1437	339	143	media	medium	NOUN
admet-1437	339	144	containing	contain	VERB
admet-1437	339	145	solubilized	solubilize	VERB
admet-1437	339	146	stabilizers	stabilizer	NOUN
admet-1437	339	147	.	.	PUNCT
admet-1437	340	1	the	the	DET
admet-1437	340	2	neat	neat	ADJ
admet-1437	340	3	drug	drug	NOUN
admet-1437	340	4	substance	substance	NOUN
admet-1437	340	5	was	be	AUX
admet-1437	340	6	characterized	characterize	VERB
admet-1437	340	7	utilizing	utilize	VERB
admet-1437	340	8	the	the	DET
admet-1437	340	9	drop	drop	NOUN
admet-1437	340	10	shape	shape	NOUN
admet-1437	340	11	analysis	analysis	NOUN
admet-1437	340	12	method	method	NOUN
admet-1437	340	13	in	in	ADP
admet-1437	340	14	an	an	DET
admet-1437	340	15	attempt	attempt	NOUN
admet-1437	340	16	to	to	PART
admet-1437	340	17	identify	identify	VERB
admet-1437	340	18	a	a	DET
admet-1437	340	19	plausible	plausible	ADJ
admet-1437	340	20	range	range	NOUN
admet-1437	340	21	for	for	ADP
admet-1437	340	22	the	the	DET
admet-1437	340	23	interfacial	interfacial	ADJ
admet-1437	340	24	energy	energy	NOUN
admet-1437	340	25	by	by	ADP
admet-1437	340	26	which	which	PRON
admet-1437	340	27	a	a	DET
admet-1437	340	28	surface	surface	NOUN
admet-1437	340	29	free	free	ADJ
admet-1437	340	30	energy	energy	NOUN
admet-1437	340	31	of	of	ADP
admet-1437	340	32	65.5	65.5	NUM
admet-1437	340	33	±	±	NUM
admet-1437	340	34	5.5	5.5	NUM
admet-1437	340	35	mj	mj	NOUN
admet-1437	340	36	/	/	SYM
admet-1437	340	37	m2	m2	PROPN
admet-1437	340	38	was	be	AUX
admet-1437	340	39	determined	determine	VERB
admet-1437	340	40	,	,	PUNCT
admet-1437	340	41	comprised	comprise	VERB
admet-1437	340	42	of	of	ADP
admet-1437	340	43	a	a	DET
admet-1437	340	44	disperse	disperse	ADJ
admet-1437	340	45	part	part	NOUN
admet-1437	340	46	of	of	ADP
admet-1437	340	47	49.5	49.5	NUM
admet-1437	340	48	±	±	NUM
admet-1437	340	49	1.1	1.1	NUM
admet-1437	340	50	mj	mj	NOUN
admet-1437	340	51	/	/	SYM
admet-1437	340	52	m2	m2	PROPN
admet-1437	340	53	and	and	CCONJ
admet-1437	340	54	a	a	DET
admet-1437	340	55	polar	polar	ADJ
admet-1437	340	56	part	part	NOUN
admet-1437	340	57	of	of	ADP
admet-1437	340	58	16.0	16.0	NUM
admet-1437	340	59	±	±	NUM
admet-1437	340	60	4.5	4.5	NUM
admet-1437	340	61	mj	mj	PROPN
admet-1437	340	62	/	/	SYM
admet-1437	340	63	m2	m2	PROPN
admet-1437	340	64	.	.	PUNCT
admet-1437	341	1	the	the	DET
admet-1437	341	2	complementary	complementary	ADJ
admet-1437	341	3	analysis	analysis	NOUN
admet-1437	341	4	by	by	ADP
admet-1437	341	5	inverse	inverse	ADJ
admet-1437	341	6	gas	gas	NOUN
admet-1437	341	7	chromatography	chromatography	NOUN
admet-1437	341	8	resulted	result	VERB
admet-1437	341	9	in	in	ADP
admet-1437	341	10	a	a	DET
admet-1437	341	11	disperse	disperse	ADJ
admet-1437	341	12	part	part	NOUN
admet-1437	341	13	of	of	ADP
admet-1437	341	14	the	the	DET
admet-1437	341	15	interfacial	interfacial	ADJ
admet-1437	341	16	energy	energy	NOUN
admet-1437	341	17	of	of	ADP
admet-1437	341	18	55	55	NUM
admet-1437	341	19	mj	mj	PROPN
admet-1437	341	20	/	/	SYM
admet-1437	341	21	m2	m2	PROPN
admet-1437	341	22	.	.	PUNCT
admet-1437	342	1	it	it	PRON
admet-1437	342	2	can	can	AUX
admet-1437	342	3	therefore	therefore	ADV
admet-1437	342	4	be	be	AUX
admet-1437	342	5	concluded	conclude	VERB
admet-1437	342	6	that	that	SCONJ
admet-1437	342	7	the	the	DET
admet-1437	342	8	interfacial	interfacial	ADJ
admet-1437	342	9	energy	energy	NOUN
admet-1437	342	10	σsl	σsl	NOUN
admet-1437	342	11	between	between	ADP
admet-1437	342	12	drug	drug	NOUN
admet-1437	342	13	nanocrystals	nanocrystal	NOUN
admet-1437	342	14	and	and	CCONJ
admet-1437	342	15	the	the	DET
admet-1437	342	16	liquid	liquid	ADJ
admet-1437	342	17	dissolution	dissolution	NOUN
admet-1437	342	18	media	medium	NOUN
admet-1437	342	19	can	can	AUX
admet-1437	342	20	be	be	AUX
admet-1437	342	21	estimated	estimate	VERB
admet-1437	342	22	to	to	PART
admet-1437	342	23	be	be	AUX
admet-1437	342	24	considerably	considerably	ADV
admet-1437	342	25	below	below	ADP
admet-1437	342	26	65	65	NUM
admet-1437	342	27	mj	mj	PROPN
admet-1437	342	28	/	/	SYM
admet-1437	342	29	m2	m2	PROPN
admet-1437	342	30	,	,	PUNCT
admet-1437	342	31	due	due	ADP
admet-1437	342	32	to	to	ADP
admet-1437	342	33	the	the	DET
admet-1437	342	34	action	action	NOUN
admet-1437	342	35	of	of	ADP
admet-1437	342	36	interfacial	interfacial	ADJ
admet-1437	342	37	energy	energy	NOUN
admet-1437	342	38	reducing	reduce	VERB
admet-1437	342	39	stabilizers	stabilizer	NOUN
admet-1437	342	40	.	.	PUNCT
admet-1437	343	1	systematic	systematic	ADJ
admet-1437	343	2	calculations	calculation	NOUN
admet-1437	343	3	were	be	AUX
admet-1437	343	4	carried	carry	VERB
admet-1437	343	5	out	out	ADP
admet-1437	343	6	with	with	ADP
admet-1437	343	7	selected	select	VERB
admet-1437	343	8	interfacial	interfacial	ADJ
admet-1437	343	9	energies	energy	NOUN
admet-1437	343	10	in	in	ADP
admet-1437	343	11	the	the	DET
admet-1437	343	12	range	range	NOUN
admet-1437	343	13	below	below	ADP
admet-1437	343	14	65	65	NUM
admet-1437	343	15	mj	mj	PROPN
admet-1437	343	16	/	/	SYM
admet-1437	343	17	m2	m2	PROPN
admet-1437	343	18	to	to	PART
admet-1437	343	19	select	select	VERB
admet-1437	343	20	interfacial	interfacial	ADJ
admet-1437	343	21	energy	energy	NOUN
admet-1437	343	22	for	for	ADP
admet-1437	343	23	the	the	DET
admet-1437	343	24	numerical	numerical	ADJ
admet-1437	343	25	calculation	calculation	NOUN
admet-1437	343	26	.	.	PUNCT
admet-1437	344	1	a	a	DET
admet-1437	344	2	comparison	comparison	NOUN
admet-1437	344	3	of	of	ADP
admet-1437	344	4	the	the	DET
admet-1437	344	5	experimentally	experimentally	ADV
admet-1437	344	6	determined	determine	VERB
admet-1437	344	7	apparent	apparent	ADJ
admet-1437	344	8	solubility	solubility	NOUN
admet-1437	344	9	from	from	ADP
admet-1437	344	10	polydisperse	polydisperse	NOUN
admet-1437	344	11	particle	particle	NOUN
admet-1437	344	12	size	size	NOUN
admet-1437	344	13	distribution	distribution	NOUN
admet-1437	344	14	,	,	PUNCT
admet-1437	344	15	according	accord	VERB
admet-1437	344	16	to	to	ADP
admet-1437	344	17	experiments	experiment	NOUN
admet-1437	344	18	no	no	INTJ
admet-1437	344	19	.	.	NOUN
admet-1437	344	20	1	1	NUM
admet-1437	344	21	to	to	PART
admet-1437	344	22	8	8	NUM
admet-1437	344	23	in	in	ADP
admet-1437	344	24	table	table	NOUN
admet-1437	344	25	7	7	NUM
admet-1437	344	26	,	,	PUNCT
admet-1437	344	27	with	with	ADP
admet-1437	344	28	the	the	DET
admet-1437	344	29	theoretical	theoretical	ADJ
admet-1437	344	30	apparent	apparent	ADJ
admet-1437	344	31	solubility	solubility	NOUN
admet-1437	344	32	calculated	calculate	VERB
admet-1437	344	33	analytically	analytically	ADV
admet-1437	344	34	using	use	VERB
admet-1437	344	35	equation	equation	NOUN
admet-1437	344	36	(	(	PUNCT
admet-1437	344	37	4	4	X
admet-1437	344	38	)	)	PUNCT
admet-1437	344	39	assuming	assume	VERB
admet-1437	344	40	a	a	DET
admet-1437	344	41	monodisperse	monodisperse	NOUN
admet-1437	344	42	particle	particle	NOUN
admet-1437	344	43	size	size	NOUN
admet-1437	344	44	for	for	ADP
admet-1437	344	45	selected	select	VERB
admet-1437	344	46	interfacial	interfacial	ADJ
admet-1437	344	47	energies	energy	NOUN
admet-1437	344	48	is	be	AUX
admet-1437	344	49	displayed	display	VERB
admet-1437	344	50	in	in	ADP
admet-1437	344	51	figure	figure	NOUN
admet-1437	344	52	7(a	7(a	NUM
admet-1437	344	53	)	)	PUNCT
admet-1437	344	54	.	.	PUNCT
admet-1437	345	1	the	the	DET
admet-1437	345	2	median	median	ADJ
admet-1437	345	3	particle	particle	NOUN
admet-1437	345	4	size	size	NOUN
admet-1437	345	5	x50,3	x50,3	PROPN
admet-1437	345	6	was	be	AUX
admet-1437	345	7	selected	select	VERB
admet-1437	345	8	as	as	ADP
admet-1437	345	9	the	the	DET
admet-1437	345	10	monodisperse	monodisperse	NOUN
admet-1437	345	11	particle	particle	NOUN
admet-1437	345	12	size	size	NOUN
admet-1437	345	13	x	x	PUNCT
admet-1437	345	14	for	for	ADP
admet-1437	345	15	the	the	DET
admet-1437	345	16	calculations	calculation	NOUN
admet-1437	345	17	.	.	PUNCT
admet-1437	346	1	the	the	DET
admet-1437	346	2	calculated	calculated	ADJ
admet-1437	346	3	theoretical	theoretical	ADJ
admet-1437	346	4	apparent	apparent	ADJ
admet-1437	346	5	solubility	solubility	NOUN
admet-1437	346	6	significantly	significantly	ADV
admet-1437	346	7	underpredicts	underpredict	VERB
admet-1437	346	8	the	the	DET
admet-1437	346	9	experimentally	experimentally	ADV
admet-1437	346	10	determined	determine	VERB
admet-1437	346	11	apparent	apparent	ADJ
admet-1437	346	12	solubility	solubility	NOUN
admet-1437	346	13	for	for	ADP
admet-1437	346	14	all	all	DET
admet-1437	346	15	selected	select	VERB
admet-1437	346	16	interfacial	interfacial	ADJ
admet-1437	346	17	energies	energy	NOUN
admet-1437	346	18	demonstrating	demonstrate	VERB
admet-1437	346	19	the	the	DET
admet-1437	346	20	clear	clear	ADJ
admet-1437	346	21	limitations	limitation	NOUN
admet-1437	346	22	of	of	ADP
admet-1437	346	23	assuming	assume	VERB
admet-1437	346	24	a	a	DET
admet-1437	346	25	monodisperse	monodisperse	NOUN
admet-1437	346	26	particle	particle	NOUN
admet-1437	346	27	size	size	NOUN
admet-1437	346	28	and	and	CCONJ
admet-1437	346	29	neglecting	neglect	VERB
admet-1437	346	30	the	the	DET
admet-1437	346	31	change	change	NOUN
admet-1437	346	32	of	of	ADP
admet-1437	346	33	particle	particle	NOUN
admet-1437	346	34	size	size	NOUN
admet-1437	346	35	distribution	distribution	NOUN
admet-1437	346	36	during	during	ADP
admet-1437	346	37	dissolution	dissolution	NOUN
admet-1437	346	38	for	for	ADP
admet-1437	346	39	a	a	DET
admet-1437	346	40	drug	drug	NOUN
admet-1437	346	41	-	-	PUNCT
admet-1437	346	42	stabilizer	stabilizer	NOUN
admet-1437	346	43	system	system	NOUN
admet-1437	346	44	containing	contain	VERB
admet-1437	346	45	drug	drug	NOUN
admet-1437	346	46	particles	particle	NOUN
admet-1437	346	47	with	with	ADP
admet-1437	346	48	a	a	DET
admet-1437	346	49	particle	particle	NOUN
admet-1437	346	50	size	size	NOUN
admet-1437	346	51	well	well	ADV
admet-1437	346	52	below	below	ADP
admet-1437	346	53	1	1	NUM
admet-1437	346	54	µm	µm	NOUN
admet-1437	346	55	.	.	PUNCT
admet-1437	346	56	figure	figure	NOUN
admet-1437	346	57	7(b	7(b	NOUN
admet-1437	346	58	)	)	PUNCT
admet-1437	346	59	shows	show	VERB
admet-1437	346	60	a	a	DET
admet-1437	346	61	comparison	comparison	NOUN
admet-1437	346	62	of	of	ADP
admet-1437	346	63	the	the	DET
admet-1437	346	64	experimentally	experimentally	ADV
admet-1437	346	65	determined	determine	VERB
admet-1437	346	66	apparent	apparent	ADJ
admet-1437	346	67	solubility	solubility	NOUN
admet-1437	346	68	from	from	ADP
admet-1437	346	69	polydisperse	polydisperse	NOUN
admet-1437	346	70	particle	particle	NOUN
admet-1437	346	71	size	size	NOUN
admet-1437	346	72	distribution	distribution	NOUN
admet-1437	346	73	,	,	PUNCT
admet-1437	346	74	according	accord	VERB
admet-1437	346	75	to	to	ADP
admet-1437	346	76	experiments	experiment	NOUN
admet-1437	346	77	no	no	INTJ
admet-1437	346	78	.	.	NOUN
admet-1437	346	79	1	1	NUM
admet-1437	346	80	to	to	PART
admet-1437	346	81	8	8	NUM
admet-1437	346	82	in	in	ADP
admet-1437	346	83	table	table	NOUN
admet-1437	346	84	7	7	NUM
admet-1437	346	85	,	,	PUNCT
admet-1437	346	86	with	with	ADP
admet-1437	346	87	the	the	DET
admet-1437	346	88	theoretical	theoretical	ADJ
admet-1437	346	89	apparent	apparent	ADJ
admet-1437	346	90	solubility	solubility	NOUN
admet-1437	346	91	calculated	calculate	VERB
admet-1437	346	92	using	use	VERB
admet-1437	346	93	the	the	DET
admet-1437	346	94	established	establish	VERB
admet-1437	346	95	numerical	numerical	ADJ
admet-1437	346	96	model	model	NOUN
admet-1437	346	97	and	and	CCONJ
admet-1437	346	98	selected	select	VERB
admet-1437	346	99	interfacial	interfacial	ADJ
admet-1437	346	100	energies	energy	NOUN
admet-1437	346	101	.	.	PUNCT
admet-1437	347	1	the	the	PRON
admet-1437	347	2	experimentally	experimentally	ADV
admet-1437	347	3	determined	determine	VERB
admet-1437	347	4	and	and	CCONJ
admet-1437	347	5	calculated	calculate	VERB
admet-1437	347	6	apparent	apparent	ADJ
admet-1437	347	7	solubility	solubility	NOUN
admet-1437	347	8	is	be	AUX
admet-1437	347	9	plotted	plot	VERB
admet-1437	347	10	against	against	ADP
admet-1437	347	11	the	the	DET
admet-1437	347	12	median	median	ADJ
admet-1437	347	13	particle	particle	NOUN
admet-1437	347	14	size	size	NOUN
admet-1437	347	15	x50,3	x50,3	PROPN
admet-1437	347	16	.	.	PUNCT
admet-1437	348	1	the	the	DET
admet-1437	348	2	consideration	consideration	NOUN
admet-1437	348	3	of	of	ADP
admet-1437	348	4	the	the	DET
admet-1437	348	5	entire	entire	ADJ
admet-1437	348	6	particle	particle	NOUN
admet-1437	348	7	size	size	NOUN
admet-1437	348	8	distribution	distribution	NOUN
admet-1437	348	9	and	and	CCONJ
admet-1437	348	10	its	its	PRON
admet-1437	348	11	change	change	NOUN
admet-1437	348	12	during	during	ADP
admet-1437	348	13	the	the	DET
admet-1437	348	14	dissolution	dissolution	NOUN
admet-1437	348	15	process	process	NOUN
admet-1437	348	16	until	until	SCONJ
admet-1437	348	17	the	the	DET
admet-1437	348	18	apparent	apparent	ADJ
admet-1437	348	19	solubility	solubility	NOUN
admet-1437	348	20	reaches	reach	VERB
admet-1437	348	21	equilibrium	equilibrium	NOUN
admet-1437	348	22	allows	allow	VERB
admet-1437	348	23	an	an	DET
admet-1437	348	24	appropriate	appropriate	ADJ
admet-1437	348	25	description	description	NOUN
admet-1437	348	26	of	of	ADP
admet-1437	348	27	the	the	DET
admet-1437	348	28	experimental	experimental	ADJ
admet-1437	348	29	data	datum	NOUN
admet-1437	348	30	.	.	PUNCT
admet-1437	349	1	the	the	DET
admet-1437	349	2	best	good	ADJ
admet-1437	349	3	agreement	agreement	NOUN
admet-1437	349	4	between	between	ADP
admet-1437	349	5	experimental	experimental	ADJ
admet-1437	349	6	and	and	CCONJ
admet-1437	349	7	calculated	calculate	VERB
admet-1437	349	8	theoretical	theoretical	ADJ
admet-1437	349	9	apparent	apparent	ADJ
admet-1437	349	10	solubility	solubility	NOUN
admet-1437	349	11	is	be	AUX
admet-1437	349	12	found	find	VERB
admet-1437	349	13	for	for	ADP
admet-1437	349	14	interfacial	interfacial	ADJ
admet-1437	349	15	energy	energy	NOUN
admet-1437	349	16	of	of	ADP
admet-1437	349	17	30	30	NUM
admet-1437	349	18	mj	mj	NOUN
admet-1437	349	19	/	/	SYM
admet-1437	349	20	m2	m2	PROPN
admet-1437	349	21	,	,	PUNCT
admet-1437	349	22	which	which	PRON
admet-1437	349	23	was	be	AUX
admet-1437	349	24	selected	select	VERB
admet-1437	349	25	for	for	ADP
admet-1437	349	26	all	all	DET
admet-1437	349	27	further	further	ADJ
admet-1437	349	28	calculations	calculation	NOUN
admet-1437	349	29	.	.	PUNCT
admet-1437	350	1	interestingly	interestingly	ADV
admet-1437	350	2	,	,	PUNCT
admet-1437	350	3	the	the	DET
admet-1437	350	4	determined	determined	ADJ
admet-1437	350	5	interfacial	interfacial	ADJ
admet-1437	350	6	admet	admet	NOUN
admet-1437	350	7	&	&	CCONJ
admet-1437	350	8	dmpk	dmpk	PROPN
admet-1437	350	9	10(4	10(4	NUM
admet-1437	350	10	)	)	PUNCT
admet-1437	350	11	(	(	PUNCT
admet-1437	350	12	2022	2022	NUM
admet-1437	350	13	)	)	PUNCT
admet-1437	350	14	253	253	NUM
admet-1437	350	15	-	-	SYM
admet-1437	350	16	287	287	NUM
admet-1437	350	17	modeling	modeling	NOUN
admet-1437	350	18	of	of	ADP
admet-1437	350	19	drug	drug	NOUN
admet-1437	350	20	nanocrystals	nanocrystal	NOUN
admet-1437	350	21	dissolution	dissolution	NOUN
admet-1437	350	22	doi	doi	PROPN
admet-1437	350	23	:	:	PUNCT
admet-1437	350	24	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	350	25	271	271	NUM
admet-1437	350	26	energy	energy	NOUN
admet-1437	350	27	is	be	AUX
admet-1437	350	28	in	in	ADP
admet-1437	350	29	good	good	ADJ
admet-1437	350	30	agreement	agreement	NOUN
admet-1437	350	31	with	with	ADP
admet-1437	350	32	the	the	DET
admet-1437	350	33	selected	select	VERB
admet-1437	350	34	interfacial	interfacial	ADJ
admet-1437	350	35	energy	energy	NOUN
admet-1437	350	36	by	by	ADP
admet-1437	350	37	jinno	jinno	NOUN
admet-1437	350	38	et	et	PROPN
admet-1437	350	39	al	al	PROPN
admet-1437	350	40	.	.	PUNCT
admet-1437	351	1	[	[	X
admet-1437	351	2	83	83	NUM
admet-1437	351	3	]	]	PUNCT
admet-1437	351	4	.	.	PUNCT
admet-1437	352	1	figure	figure	NOUN
admet-1437	352	2	7	7	NUM
admet-1437	352	3	.	.	PUNCT
admet-1437	352	4	experimentally	experimentally	ADV
admet-1437	352	5	determined	determine	VERB
admet-1437	352	6	apparent	apparent	ADJ
admet-1437	352	7	solubility	solubility	NOUN
admet-1437	352	8	(	(	PUNCT
admet-1437	352	9	sapp	sapp	PROPN
admet-1437	352	10	,	,	PUNCT
admet-1437	352	11	exp	exp	NOUN
admet-1437	352	12	)	)	PUNCT
admet-1437	352	13	of	of	ADP
admet-1437	352	14	polydisperse	polydisperse	NOUN
admet-1437	352	15	particle	particle	NOUN
admet-1437	352	16	size	size	NOUN
admet-1437	352	17	distributions	distribution	NOUN
admet-1437	352	18	according	accord	VERB
admet-1437	352	19	to	to	ADP
admet-1437	352	20	table	table	NOUN
admet-1437	352	21	7	7	NUM
admet-1437	352	22	in	in	ADP
admet-1437	352	23	ph	ph	ADJ
admet-1437	352	24	3	3	NUM
admet-1437	352	25	dissolution	dissolution	NOUN
admet-1437	352	26	media	medium	NOUN
admet-1437	352	27	at	at	ADP
admet-1437	352	28	constant	constant	ADJ
admet-1437	352	29	ratio	ratio	NOUN
admet-1437	352	30	of	of	ADP
admet-1437	352	31	drug	drug	NOUN
admet-1437	352	32	/	/	SYM
admet-1437	352	33	dissolution	dissolution	NOUN
admet-1437	352	34	media	medium	NOUN
admet-1437	352	35	(	(	PUNCT
admet-1437	352	36	do	do	AUX
admet-1437	352	37	=	=	SYM
admet-1437	352	38	8.9	8.9	NUM
admet-1437	352	39	)	)	PUNCT
admet-1437	352	40	vs	vs	ADP
admet-1437	352	41	theoretical	theoretical	ADJ
admet-1437	352	42	calculated	calculate	VERB
admet-1437	352	43	apparent	apparent	ADJ
admet-1437	352	44	solubility	solubility	NOUN
admet-1437	352	45	(	(	PUNCT
admet-1437	352	46	sapp	sapp	PROPN
admet-1437	352	47	,	,	PUNCT
admet-1437	352	48	th	th	X
admet-1437	352	49	)	)	PUNCT
admet-1437	352	50	for	for	ADP
admet-1437	352	51	selected	select	VERB
admet-1437	352	52	interfacial	interfacial	ADJ
admet-1437	352	53	energies	energy	NOUN
admet-1437	352	54	plotted	plot	VERB
admet-1437	352	55	against	against	ADP
admet-1437	352	56	particle	particle	NOUN
admet-1437	352	57	size	size	NOUN
admet-1437	352	58	.	.	PUNCT
admet-1437	353	1	(	(	PUNCT
admet-1437	353	2	a	a	X
admet-1437	353	3	)	)	PUNCT
admet-1437	353	4	comparison	comparison	NOUN
admet-1437	353	5	of	of	ADP
admet-1437	353	6	theoretical	theoretical	ADJ
admet-1437	353	7	apparent	apparent	ADJ
admet-1437	353	8	solubility	solubility	NOUN
admet-1437	353	9	(	(	PUNCT
admet-1437	353	10	sapp	sapp	PROPN
admet-1437	353	11	,	,	PUNCT
admet-1437	353	12	th	th	X
admet-1437	353	13	)	)	PUNCT
admet-1437	353	14	with	with	ADP
admet-1437	353	15	monodisperse	monodisperse	NOUN
admet-1437	353	16	particle	particle	NOUN
admet-1437	353	17	size	size	NOUN
admet-1437	353	18	x	x	PUNCT
admet-1437	353	19	=	=	SYM
admet-1437	353	20	x50,3	x50,3	PROPN
admet-1437	353	21	using	use	VERB
admet-1437	353	22	analytical	analytical	ADJ
admet-1437	353	23	calculation	calculation	NOUN
admet-1437	353	24	(	(	PUNCT
admet-1437	353	25	equation	equation	NOUN
admet-1437	353	26	(	(	PUNCT
admet-1437	353	27	4	4	NUM
admet-1437	353	28	)	)	PUNCT
admet-1437	353	29	)	)	PUNCT
admet-1437	353	30	vs	vs	ADP
admet-1437	353	31	experimentally	experimentally	ADV
admet-1437	353	32	determined	determine	VERB
admet-1437	353	33	apparent	apparent	ADJ
admet-1437	353	34	solubility	solubility	NOUN
admet-1437	353	35	(	(	PUNCT
admet-1437	353	36	sapp	sapp	PROPN
admet-1437	353	37	,	,	PUNCT
admet-1437	353	38	exp	exp	NOUN
admet-1437	353	39	)	)	PUNCT
admet-1437	353	40	with	with	ADP
admet-1437	353	41	polydisperse	polydisperse	NOUN
admet-1437	353	42	particle	particle	NOUN
admet-1437	353	43	size	size	NOUN
admet-1437	353	44	distribution	distribution	NOUN
admet-1437	353	45	.	.	PUNCT
admet-1437	354	1	(	(	PUNCT
admet-1437	354	2	b	b	X
admet-1437	354	3	)	)	PUNCT
admet-1437	354	4	comparison	comparison	NOUN
admet-1437	354	5	of	of	ADP
admet-1437	354	6	theoretical	theoretical	ADJ
admet-1437	354	7	apparent	apparent	ADJ
admet-1437	354	8	solubility	solubility	NOUN
admet-1437	354	9	(	(	PUNCT
admet-1437	354	10	sapp	sapp	PROPN
admet-1437	354	11	,	,	PUNCT
admet-1437	354	12	th	th	X
admet-1437	354	13	)	)	PUNCT
admet-1437	354	14	with	with	ADP
admet-1437	354	15	polydisperse	polydisperse	NOUN
admet-1437	354	16	particle	particle	NOUN
admet-1437	354	17	size	size	NOUN
admet-1437	354	18	distributions	distribution	NOUN
admet-1437	354	19	according	accord	VERB
admet-1437	354	20	to	to	ADP
admet-1437	354	21	table	table	NOUN
admet-1437	354	22	2	2	NUM
admet-1437	354	23	using	use	VERB
admet-1437	354	24	numerical	numerical	ADJ
admet-1437	354	25	calculation	calculation	NOUN
admet-1437	354	26	vs.	vs.	ADP
admet-1437	354	27	experimentally	experimentally	ADV
admet-1437	354	28	determined	determine	VERB
admet-1437	354	29	apparent	apparent	ADJ
admet-1437	354	30	solubility	solubility	NOUN
admet-1437	354	31	(	(	PUNCT
admet-1437	354	32	sapp	sapp	PROPN
admet-1437	354	33	,	,	PUNCT
admet-1437	354	34	exp	exp	NOUN
admet-1437	354	35	)	)	PUNCT
admet-1437	354	36	with	with	ADP
admet-1437	354	37	polydisperse	polydisperse	NOUN
admet-1437	354	38	particle	particle	NOUN
admet-1437	354	39	size	size	NOUN
admet-1437	354	40	distribution	distribution	NOUN
admet-1437	354	41	.	.	PUNCT
admet-1437	355	1	in	in	ADP
admet-1437	355	2	addition	addition	NOUN
admet-1437	355	3	to	to	ADP
admet-1437	355	4	the	the	DET
admet-1437	355	5	results	result	NOUN
admet-1437	355	6	reported	report	VERB
admet-1437	355	7	in	in	ADP
admet-1437	355	8	table	table	NOUN
admet-1437	355	9	7	7	NUM
admet-1437	355	10	for	for	ADP
admet-1437	355	11	the	the	DET
admet-1437	355	12	apparent	apparent	ADJ
admet-1437	355	13	solubility	solubility	NOUN
admet-1437	355	14	determined	determine	VERB
admet-1437	355	15	in	in	ADP
admet-1437	355	16	ph	ph	ADJ
admet-1437	355	17	3	3	NUM
admet-1437	355	18	citrate	citrate	NOUN
admet-1437	355	19	buffer	buffer	NOUN
admet-1437	355	20	,	,	PUNCT
admet-1437	355	21	the	the	DET
admet-1437	355	22	apparent	apparent	ADJ
admet-1437	355	23	solubility	solubility	NOUN
admet-1437	355	24	was	be	AUX
admet-1437	355	25	experimentally	experimentally	ADV
admet-1437	355	26	determined	determine	VERB
admet-1437	355	27	for	for	ADP
admet-1437	355	28	0.01	0.01	NUM
admet-1437	355	29	m	m	PROPN
admet-1437	355	30	hydrochloric	hydrochloric	ADJ
admet-1437	355	31	acid	acid	NOUN
admet-1437	355	32	ph	ph	VERB
admet-1437	355	33	2	2	NUM
admet-1437	355	34	solution	solution	NOUN
admet-1437	355	35	and	and	CCONJ
admet-1437	355	36	ph	ph	ADJ
admet-1437	355	37	4.5	4.5	NUM
admet-1437	355	38	sodium	sodium	NOUN
admet-1437	355	39	acetate	acetate	NOUN
admet-1437	355	40	buffer	buffer	NOUN
admet-1437	355	41	,	,	PUNCT
admet-1437	355	42	using	use	VERB
admet-1437	355	43	partly	partly	ADV
admet-1437	355	44	the	the	DET
admet-1437	355	45	same	same	ADJ
admet-1437	355	46	but	but	CCONJ
admet-1437	355	47	also	also	ADV
admet-1437	355	48	additional	additional	ADJ
admet-1437	355	49	nanocrystal	nanocrystal	ADJ
admet-1437	355	50	suspensions	suspension	NOUN
admet-1437	355	51	(	(	PUNCT
admet-1437	355	52	data	datum	NOUN
admet-1437	355	53	not	not	PART
admet-1437	355	54	shown	show	VERB
admet-1437	355	55	)	)	PUNCT
admet-1437	355	56	,	,	PUNCT
admet-1437	355	57	while	while	SCONJ
admet-1437	355	58	maintaining	maintain	VERB
admet-1437	355	59	comparable	comparable	ADJ
admet-1437	355	60	do	do	VERB
admet-1437	355	61	values	value	NOUN
admet-1437	355	62	.	.	PUNCT
admet-1437	356	1	figure	figure	VERB
admet-1437	356	2	8	8	NUM
admet-1437	356	3	displays	display	VERB
admet-1437	356	4	the	the	DET
admet-1437	356	5	experimentally	experimentally	ADV
admet-1437	356	6	determined	determine	VERB
admet-1437	356	7	apparent	apparent	ADJ
admet-1437	356	8	solubility	solubility	NOUN
admet-1437	356	9	for	for	ADP
admet-1437	356	10	all	all	DET
admet-1437	356	11	three	three	NUM
admet-1437	356	12	dissolution	dissolution	ADJ
admet-1437	356	13	media	medium	NOUN
admet-1437	356	14	in	in	ADP
admet-1437	356	15	comparison	comparison	NOUN
admet-1437	356	16	to	to	ADP
admet-1437	356	17	the	the	DET
admet-1437	356	18	theoretical	theoretical	ADJ
admet-1437	356	19	apparent	apparent	ADJ
admet-1437	356	20	solubility	solubility	NOUN
admet-1437	356	21	calculated	calculate	VERB
admet-1437	356	22	by	by	ADP
admet-1437	356	23	the	the	DET
admet-1437	356	24	numerical	numerical	PROPN
admet-1437	356	25	model	model	PROPN
admet-1437	356	26	using	use	VERB
admet-1437	356	27	interfacial	interfacial	ADJ
admet-1437	356	28	energy	energy	NOUN
admet-1437	356	29	of	of	ADP
admet-1437	356	30	30	30	NUM
admet-1437	356	31	mj	mj	NOUN
admet-1437	356	32	/	/	SYM
admet-1437	356	33	m2	m2	PROPN
admet-1437	356	34	.	.	PUNCT
admet-1437	357	1	the	the	DET
admet-1437	357	2	data	datum	NOUN
admet-1437	357	3	set	set	VERB
admet-1437	357	4	demonstrates	demonstrate	VERB
admet-1437	357	5	the	the	DET
admet-1437	357	6	applicability	applicability	NOUN
admet-1437	357	7	of	of	ADP
admet-1437	357	8	the	the	DET
admet-1437	357	9	model	model	NOUN
admet-1437	357	10	to	to	ADP
admet-1437	357	11	various	various	ADJ
admet-1437	357	12	aqueous	aqueous	ADJ
admet-1437	357	13	dissolution	dissolution	NOUN
admet-1437	357	14	media	medium	NOUN
admet-1437	357	15	with	with	ADP
admet-1437	357	16	different	different	ADJ
admet-1437	357	17	levels	level	NOUN
admet-1437	357	18	of	of	ADP
admet-1437	357	19	thermodynamic	thermodynamic	ADJ
admet-1437	357	20	solubility	solubility	NOUN
admet-1437	357	21	across	across	ADP
admet-1437	357	22	about	about	ADV
admet-1437	357	23	two	two	NUM
admet-1437	357	24	orders	order	NOUN
admet-1437	357	25	of	of	ADP
admet-1437	357	26	magnitude	magnitude	NOUN
admet-1437	357	27	.	.	PUNCT
admet-1437	358	1	the	the	DET
admet-1437	358	2	relative	relative	ADJ
admet-1437	358	3	change	change	NOUN
admet-1437	358	4	in	in	ADP
admet-1437	358	5	solubility	solubility	NOUN
admet-1437	358	6	s	s	PART
admet-1437	358	7	/	/	SYM
admet-1437	358	8	s0	s0	PROPN
admet-1437	358	9	as	as	SCONJ
admet-1437	358	10	described	describe	VERB
admet-1437	358	11	by	by	ADP
admet-1437	358	12	equation	equation	NOUN
admet-1437	358	13	(	(	PUNCT
admet-1437	358	14	4	4	NUM
admet-1437	358	15	)	)	PUNCT
admet-1437	358	16	is	be	AUX
admet-1437	358	17	the	the	DET
admet-1437	358	18	same	same	ADJ
admet-1437	358	19	for	for	ADP
admet-1437	358	20	any	any	DET
admet-1437	358	21	media	medium	NOUN
admet-1437	358	22	,	,	PUNCT
admet-1437	358	23	independent	independent	ADJ
admet-1437	358	24	of	of	ADP
admet-1437	358	25	the	the	DET
admet-1437	358	26	absolute	absolute	ADJ
admet-1437	358	27	value	value	NOUN
admet-1437	358	28	of	of	ADP
admet-1437	358	29	the	the	DET
admet-1437	358	30	thermodynamic	thermodynamic	ADJ
admet-1437	358	31	solubility	solubility	NOUN
admet-1437	358	32	if	if	SCONJ
admet-1437	358	33	do	do	AUX
admet-1437	358	34	is	be	AUX
admet-1437	358	35	kept	keep	VERB
admet-1437	358	36	constant	constant	ADJ
admet-1437	358	37	.	.	PUNCT
admet-1437	359	1	consequently	consequently	ADV
admet-1437	359	2	,	,	PUNCT
admet-1437	359	3	the	the	DET
admet-1437	359	4	relative	relative	ADJ
admet-1437	359	5	change	change	NOUN
admet-1437	359	6	of	of	ADP
admet-1437	359	7	apparent	apparent	ADJ
admet-1437	359	8	solubility	solubility	NOUN
admet-1437	359	9	shown	show	VERB
admet-1437	359	10	in	in	ADP
admet-1437	359	11	figure	figure	NOUN
admet-1437	359	12	8	8	NUM
admet-1437	359	13	is	be	AUX
admet-1437	359	14	the	the	DET
admet-1437	359	15	same	same	ADJ
admet-1437	359	16	for	for	ADP
admet-1437	359	17	all	all	DET
admet-1437	359	18	three	three	NUM
admet-1437	359	19	investigated	investigate	VERB
admet-1437	359	20	dissolution	dissolution	NOUN
admet-1437	359	21	media	medium	NOUN
admet-1437	359	22	.	.	PUNCT
admet-1437	360	1	it	it	PRON
admet-1437	360	2	should	should	AUX
admet-1437	360	3	be	be	AUX
admet-1437	360	4	particularly	particularly	ADV
admet-1437	360	5	highlighted	highlight	VERB
admet-1437	360	6	that	that	SCONJ
admet-1437	360	7	the	the	DET
admet-1437	360	8	experimental	experimental	ADJ
admet-1437	360	9	and	and	CCONJ
admet-1437	360	10	calculated	calculate	VERB
admet-1437	360	11	results	result	NOUN
admet-1437	360	12	are	be	AUX
admet-1437	360	13	quite	quite	ADV
admet-1437	360	14	conclusive	conclusive	ADJ
admet-1437	360	15	according	accord	VERB
admet-1437	360	16	to	to	ADP
admet-1437	360	17	the	the	DET
admet-1437	360	18	noyes	noyes	PROPN
admet-1437	360	19	-	-	PUNCT
admet-1437	360	20	whitney	whitney	PROPN
admet-1437	360	21	/	/	SYM
admet-1437	360	22	nernst	nernst	PROPN
admet-1437	360	23	-	-	PUNCT
admet-1437	360	24	brunner	brunner	PROPN
admet-1437	360	25	and	and	CCONJ
admet-1437	360	26	ostwald	ostwald	NOUN
admet-1437	360	27	-	-	PUNCT
admet-1437	360	28	freundlich	freundlich	ADJ
admet-1437	360	29	equations	equation	NOUN
admet-1437	360	30	.	.	PUNCT
admet-1437	361	1	interestingly	interestingly	ADV
admet-1437	361	2	,	,	PUNCT
admet-1437	361	3	the	the	DET
admet-1437	361	4	results	result	NOUN
admet-1437	361	5	obtained	obtain	VERB
admet-1437	361	6	for	for	ADP
admet-1437	361	7	apparent	apparent	ADJ
admet-1437	361	8	solubility	solubility	NOUN
admet-1437	361	9	against	against	ADP
admet-1437	361	10	drug	drug	NOUN
admet-1437	361	11	particle	particle	NOUN
admet-1437	361	12	size	size	NOUN
admet-1437	361	13	,	,	PUNCT
admet-1437	361	14	see	see	VERB
admet-1437	361	15	figure	figure	NOUN
admet-1437	361	16	7	7	NUM
admet-1437	361	17	,	,	PUNCT
admet-1437	361	18	coincide	coincide	VERB
admet-1437	361	19	in	in	ADP
admet-1437	361	20	trend	trend	NOUN
admet-1437	361	21	with	with	ADP
admet-1437	361	22	the	the	DET
admet-1437	361	23	results	result	NOUN
admet-1437	361	24	obtained	obtain	VERB
admet-1437	361	25	on	on	ADP
admet-1437	361	26	the	the	DET
admet-1437	361	27	hypothesized	hypothesized	ADJ
admet-1437	361	28	intrinsic	intrinsic	ADJ
admet-1437	361	29	amorphous	amorphous	ADJ
admet-1437	361	30	surface	surface	NOUN
admet-1437	361	31	layer	layer	NOUN
admet-1437	361	32	,	,	PUNCT
admet-1437	361	33	see	see	VERB
admet-1437	361	34	figure	figure	NOUN
admet-1437	361	35	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	361	36	bonhoeffer	bonhoeffer	PROPN
admet-1437	361	37	et	et	PROPN
admet-1437	361	38	al	al	PROPN
admet-1437	361	39	.	.	PROPN
admet-1437	361	40	admet	admet	PROPN
admet-1437	361	41	&	&	CCONJ
admet-1437	361	42	dmpk	dmpk	PROPN
admet-1437	361	43	10(4	10(4	NUM
admet-1437	361	44	)	)	PUNCT
admet-1437	361	45	(	(	PUNCT
admet-1437	361	46	2022	2022	NUM
admet-1437	361	47	)	)	PUNCT
admet-1437	361	48	253	253	NUM
admet-1437	361	49	-	-	SYM
admet-1437	361	50	287	287	NUM
admet-1437	361	51	272	272	NUM
admet-1437	361	52	3(b	3(b	NUM
admet-1437	361	53	)	)	PUNCT
admet-1437	361	54	and	and	CCONJ
admet-1437	361	55	table	table	NOUN
admet-1437	361	56	3	3	NUM
admet-1437	361	57	.	.	PUNCT
admet-1437	362	1	a	a	DET
admet-1437	362	2	potential	potential	ADJ
admet-1437	362	3	relationship	relationship	NOUN
admet-1437	362	4	between	between	ADP
admet-1437	362	5	the	the	DET
admet-1437	362	6	increase	increase	NOUN
admet-1437	362	7	in	in	ADP
admet-1437	362	8	apparent	apparent	ADJ
admet-1437	362	9	solubility	solubility	NOUN
admet-1437	362	10	and	and	CCONJ
admet-1437	362	11	the	the	DET
admet-1437	362	12	increase	increase	NOUN
admet-1437	362	13	of	of	ADP
admet-1437	362	14	the	the	DET
admet-1437	362	15	hypothesized	hypothesized	ADJ
admet-1437	362	16	intrinsic	intrinsic	ADJ
admet-1437	362	17	surface	surface	NOUN
admet-1437	362	18	amorphicity	amorphicity	NOUN
admet-1437	362	19	was	be	AUX
admet-1437	362	20	not	not	PART
admet-1437	362	21	further	far	ADV
admet-1437	362	22	investigated	investigate	VERB
admet-1437	362	23	in	in	ADP
admet-1437	362	24	this	this	DET
admet-1437	362	25	study	study	NOUN
admet-1437	362	26	.	.	PUNCT
admet-1437	363	1	figure	figure	NOUN
admet-1437	363	2	8	8	NUM
admet-1437	363	3	.	.	PUNCT
admet-1437	363	4	experimentally	experimentally	ADV
admet-1437	363	5	determined	determine	VERB
admet-1437	363	6	apparent	apparent	ADJ
admet-1437	363	7	solubility	solubility	NOUN
admet-1437	363	8	(	(	PUNCT
admet-1437	363	9	sapp	sapp	PROPN
admet-1437	363	10	,	,	PUNCT
admet-1437	363	11	exp	exp	NOUN
admet-1437	363	12	)	)	PUNCT
admet-1437	363	13	of	of	ADP
admet-1437	363	14	polydisperse	polydisperse	NOUN
admet-1437	363	15	particle	particle	NOUN
admet-1437	363	16	size	size	NOUN
admet-1437	363	17	distributions	distribution	NOUN
admet-1437	363	18	in	in	ADP
admet-1437	363	19	ph	ph	ADJ
admet-1437	363	20	2	2	NUM
admet-1437	363	21	,	,	PUNCT
admet-1437	363	22	ph	ph	NOUN
admet-1437	363	23	3	3	NUM
admet-1437	363	24	and	and	CCONJ
admet-1437	363	25	ph	ph	ADJ
admet-1437	363	26	4.5	4.5	NUM
admet-1437	363	27	dissolution	dissolution	NOUN
admet-1437	363	28	media	medium	NOUN
admet-1437	363	29	vs	vs	ADP
admet-1437	363	30	theoretical	theoretical	ADJ
admet-1437	363	31	calculated	calculate	VERB
admet-1437	363	32	apparent	apparent	ADJ
admet-1437	363	33	solubility	solubility	NOUN
admet-1437	363	34	(	(	PUNCT
admet-1437	363	35	sapp	sapp	PROPN
admet-1437	363	36	,	,	PUNCT
admet-1437	363	37	th	th	X
admet-1437	363	38	)	)	PUNCT
admet-1437	363	39	for	for	ADP
admet-1437	363	40	polydisperse	polydisperse	NOUN
admet-1437	363	41	particle	particle	NOUN
admet-1437	363	42	size	size	NOUN
admet-1437	363	43	distributions	distribution	NOUN
admet-1437	363	44	according	accord	VERB
admet-1437	363	45	to	to	ADP
admet-1437	363	46	table	table	NOUN
admet-1437	363	47	2	2	NUM
admet-1437	363	48	and	and	CCONJ
admet-1437	363	49	interfacial	interfacial	ADJ
admet-1437	363	50	energy	energy	NOUN
admet-1437	363	51	of	of	ADP
admet-1437	363	52	30	30	NUM
admet-1437	363	53	mj	mj	NOUN
admet-1437	363	54	/	/	SYM
admet-1437	363	55	m2	m2	PROPN
admet-1437	363	56	using	use	VERB
admet-1437	363	57	numerical	numerical	ADJ
admet-1437	363	58	calculation	calculation	NOUN
admet-1437	363	59	with	with	ADP
admet-1437	363	60	representation	representation	NOUN
admet-1437	363	61	against	against	ADP
admet-1437	363	62	median	median	ADJ
admet-1437	363	63	particle	particle	NOUN
admet-1437	363	64	size	size	NOUN
admet-1437	363	65	x50,3	x50,3	PROPN
admet-1437	363	66	.	.	PUNCT
admet-1437	364	1	a	a	DET
admet-1437	364	2	comparison	comparison	NOUN
admet-1437	364	3	of	of	ADP
admet-1437	364	4	the	the	DET
admet-1437	364	5	experimentally	experimentally	ADV
admet-1437	364	6	determined	determine	VERB
admet-1437	364	7	apparent	apparent	ADJ
admet-1437	364	8	solubility	solubility	NOUN
admet-1437	364	9	from	from	ADP
admet-1437	364	10	the	the	DET
admet-1437	364	11	same	same	ADJ
admet-1437	364	12	polydisperse	polydisperse	NOUN
admet-1437	364	13	particle	particle	NOUN
admet-1437	364	14	size	size	NOUN
admet-1437	364	15	distribution	distribution	NOUN
admet-1437	364	16	(	(	PUNCT
admet-1437	364	17	x50,3	x50,3	SYM
admet-1437	364	18	=	=	SYM
admet-1437	364	19	111	111	NUM
admet-1437	364	20	nm	nm	NOUN
admet-1437	364	21	)	)	PUNCT
admet-1437	364	22	,	,	PUNCT
admet-1437	364	23	applying	apply	VERB
admet-1437	364	24	different	different	ADJ
admet-1437	364	25	do	do	AUX
admet-1437	364	26	values	value	NOUN
admet-1437	364	27	according	accord	VERB
admet-1437	364	28	to	to	ADP
admet-1437	364	29	experiments	experiment	NOUN
admet-1437	364	30	no	no	INTJ
admet-1437	364	31	.	.	NOUN
admet-1437	364	32	9	9	NUM
admet-1437	364	33	to	to	ADP
admet-1437	364	34	14	14	NUM
admet-1437	364	35	in	in	ADP
admet-1437	364	36	table	table	NOUN
admet-1437	364	37	7	7	NUM
admet-1437	364	38	,	,	PUNCT
admet-1437	364	39	with	with	ADP
admet-1437	364	40	the	the	DET
admet-1437	364	41	theoretical	theoretical	ADJ
admet-1437	364	42	apparent	apparent	ADJ
admet-1437	364	43	solubility	solubility	NOUN
admet-1437	364	44	calculated	calculate	VERB
admet-1437	364	45	by	by	ADP
admet-1437	364	46	the	the	DET
admet-1437	364	47	established	establish	VERB
admet-1437	364	48	numerical	numerical	ADJ
admet-1437	364	49	model	model	NOUN
admet-1437	364	50	is	be	AUX
admet-1437	364	51	shown	show	VERB
admet-1437	364	52	in	in	ADP
admet-1437	364	53	figure	figure	NOUN
admet-1437	364	54	9	9	NUM
admet-1437	364	55	.	.	PUNCT
admet-1437	364	56	using	use	VERB
admet-1437	364	57	the	the	DET
admet-1437	364	58	fitted	fit	VERB
admet-1437	364	59	width	width	NOUN
admet-1437	364	60	of	of	ADP
admet-1437	364	61	the	the	DET
admet-1437	364	62	psd	psd	PROPN
admet-1437	364	63	σ	σ	PROPN
admet-1437	364	64	=	=	PROPN
admet-1437	364	65	0.51	0.51	NUM
admet-1437	364	66	,	,	PUNCT
admet-1437	364	67	the	the	DET
admet-1437	364	68	calculated	calculated	ADJ
admet-1437	364	69	apparent	apparent	ADJ
admet-1437	364	70	solubility	solubility	NOUN
admet-1437	364	71	increases	increase	VERB
admet-1437	364	72	with	with	ADP
admet-1437	364	73	increasing	increase	VERB
admet-1437	364	74	do	do	AUX
admet-1437	364	75	values	value	NOUN
admet-1437	364	76	comparable	comparable	ADJ
admet-1437	364	77	to	to	ADP
admet-1437	364	78	the	the	DET
admet-1437	364	79	observations	observation	NOUN
admet-1437	364	80	for	for	ADP
admet-1437	364	81	the	the	DET
admet-1437	364	82	experimental	experimental	ADJ
admet-1437	364	83	data	datum	NOUN
admet-1437	364	84	,	,	PUNCT
admet-1437	364	85	demonstrating	demonstrate	VERB
admet-1437	364	86	that	that	SCONJ
admet-1437	364	87	the	the	DET
admet-1437	364	88	numerical	numerical	ADJ
admet-1437	364	89	model	model	NOUN
admet-1437	364	90	can	can	AUX
admet-1437	364	91	successfully	successfully	ADV
admet-1437	364	92	capture	capture	VERB
admet-1437	364	93	this	this	DET
admet-1437	364	94	behavior	behavior	NOUN
admet-1437	364	95	,	,	PUNCT
admet-1437	364	96	which	which	PRON
admet-1437	364	97	would	would	AUX
admet-1437	364	98	not	not	PART
admet-1437	364	99	be	be	AUX
admet-1437	364	100	possible	possible	ADJ
admet-1437	364	101	by	by	ADP
admet-1437	364	102	assuming	assume	VERB
admet-1437	364	103	a	a	DET
admet-1437	364	104	monodisperse	monodisperse	NOUN
admet-1437	364	105	particle	particle	NOUN
admet-1437	364	106	size	size	NOUN
admet-1437	364	107	.	.	PUNCT
admet-1437	365	1	however	however	ADV
admet-1437	365	2	,	,	PUNCT
admet-1437	365	3	while	while	SCONJ
admet-1437	365	4	the	the	DET
admet-1437	365	5	experimental	experimental	ADJ
admet-1437	365	6	data	datum	NOUN
admet-1437	365	7	form	form	VERB
admet-1437	365	8	a	a	DET
admet-1437	365	9	distinct	distinct	ADJ
admet-1437	365	10	plateau	plateau	NOUN
admet-1437	365	11	,	,	PUNCT
admet-1437	365	12	the	the	DET
admet-1437	365	13	calculated	calculated	ADJ
admet-1437	365	14	apparent	apparent	ADJ
admet-1437	365	15	solubility	solubility	NOUN
admet-1437	365	16	keeps	keep	VERB
admet-1437	365	17	increasing	increase	VERB
admet-1437	365	18	and	and	CCONJ
admet-1437	365	19	levels	level	NOUN
admet-1437	365	20	off	off	ADP
admet-1437	365	21	much	much	ADV
admet-1437	365	22	slower	slow	ADJ
admet-1437	365	23	.	.	PUNCT
admet-1437	366	1	for	for	ADP
admet-1437	366	2	the	the	DET
admet-1437	366	3	calculation	calculation	NOUN
admet-1437	366	4	the	the	DET
admet-1437	366	5	interfacial	interfacial	ADJ
admet-1437	366	6	energy	energy	NOUN
admet-1437	366	7	value	value	NOUN
admet-1437	366	8	of	of	ADP
admet-1437	366	9	30	30	NUM
admet-1437	366	10	mj	mj	NOUN
admet-1437	366	11	/	/	SYM
admet-1437	366	12	m2	m2	PROPN
admet-1437	366	13	was	be	AUX
admet-1437	366	14	used	use	VERB
admet-1437	366	15	,	,	PUNCT
admet-1437	366	16	which	which	PRON
admet-1437	366	17	was	be	AUX
admet-1437	366	18	obtained	obtain	VERB
admet-1437	366	19	by	by	ADP
admet-1437	366	20	fitting	fitting	ADJ
admet-1437	366	21	data	datum	NOUN
admet-1437	366	22	from	from	ADP
admet-1437	366	23	experiments	experiment	NOUN
admet-1437	366	24	no	no	INTJ
admet-1437	366	25	.	.	NOUN
admet-1437	366	26	1	1	NUM
admet-1437	366	27	to	to	PART
admet-1437	366	28	8	8	NUM
admet-1437	366	29	with	with	ADP
admet-1437	366	30	a	a	DET
admet-1437	366	31	fixed	fix	VERB
admet-1437	366	32	do	do	NOUN
admet-1437	366	33	=	=	NOUN
admet-1437	366	34	8.9	8.9	NUM
admet-1437	366	35	.	.	PUNCT
admet-1437	367	1	for	for	ADP
admet-1437	367	2	lower	low	ADJ
admet-1437	367	3	do	do	VERB
admet-1437	367	4	values	value	NOUN
admet-1437	367	5	,	,	PUNCT
admet-1437	367	6	the	the	DET
admet-1437	367	7	numerical	numerical	ADJ
admet-1437	367	8	model	model	NOUN
admet-1437	367	9	seems	seem	VERB
admet-1437	367	10	to	to	PART
admet-1437	367	11	underpredict	underpredict	VERB
admet-1437	367	12	the	the	DET
admet-1437	367	13	apparent	apparent	ADJ
admet-1437	367	14	solubility	solubility	NOUN
admet-1437	367	15	while	while	SCONJ
admet-1437	367	16	overpredicting	overpredicte	VERB
admet-1437	367	17	for	for	ADP
admet-1437	367	18	higher	high	ADJ
admet-1437	367	19	do	do	AUX
admet-1437	367	20	values	value	NOUN
admet-1437	367	21	.	.	PUNCT
admet-1437	368	1	potential	potential	ADJ
admet-1437	368	2	root	root	NOUN
admet-1437	368	3	causes	cause	NOUN
admet-1437	368	4	for	for	ADP
admet-1437	368	5	the	the	DET
admet-1437	368	6	observed	observed	ADJ
admet-1437	368	7	discrepancy	discrepancy	NOUN
admet-1437	368	8	include	include	VERB
admet-1437	368	9	:	:	PUNCT
admet-1437	368	10	1	1	X
admet-1437	368	11	)	)	PUNCT
admet-1437	368	12	no	no	DET
admet-1437	368	13	consideration	consideration	NOUN
admet-1437	368	14	of	of	ADP
admet-1437	368	15	particle	particle	NOUN
admet-1437	368	16	morphology	morphology	NOUN
admet-1437	368	17	(	(	PUNCT
admet-1437	368	18	assumption	assumption	NOUN
admet-1437	368	19	of	of	ADP
admet-1437	368	20	spherical	spherical	ADJ
admet-1437	368	21	particles	particle	NOUN
admet-1437	368	22	)	)	PUNCT
admet-1437	368	23	,	,	PUNCT
admet-1437	368	24	2	2	X
admet-1437	368	25	)	)	PUNCT
admet-1437	368	26	uncertainty	uncertainty	NOUN
admet-1437	368	27	on	on	ADP
admet-1437	368	28	experimentally	experimentally	ADV
admet-1437	368	29	determined	determine	VERB
admet-1437	368	30	and	and	CCONJ
admet-1437	368	31	fitted	fit	VERB
admet-1437	368	32	particle	particle	NOUN
admet-1437	368	33	size	size	NOUN
admet-1437	368	34	distribution	distribution	NOUN
admet-1437	368	35	,	,	PUNCT
admet-1437	368	36	especially	especially	ADV
admet-1437	368	37	regarding	regard	VERB
admet-1437	368	38	the	the	DET
admet-1437	368	39	overestimation	overestimation	NOUN
admet-1437	368	40	of	of	ADP
admet-1437	368	41	the	the	DET
admet-1437	368	42	fine	fine	ADJ
admet-1437	368	43	fraction	fraction	NOUN
admet-1437	368	44	.	.	PUNCT
admet-1437	369	1	of	of	ADP
admet-1437	369	2	these	these	DET
admet-1437	369	3	two	two	NUM
admet-1437	369	4	potential	potential	ADJ
admet-1437	369	5	root	root	NOUN
admet-1437	369	6	causes	cause	NOUN
admet-1437	369	7	,	,	PUNCT
admet-1437	369	8	the	the	DET
admet-1437	369	9	latter	latter	ADJ
admet-1437	369	10	was	be	AUX
admet-1437	369	11	investigated	investigate	VERB
admet-1437	369	12	by	by	ADP
admet-1437	369	13	systematic	systematic	ADJ
admet-1437	369	14	variation	variation	NOUN
admet-1437	369	15	of	of	ADP
admet-1437	369	16	the	the	DET
admet-1437	369	17	particle	particle	NOUN
admet-1437	369	18	size	size	NOUN
admet-1437	369	19	distribution	distribution	NOUN
admet-1437	369	20	at	at	ADP
admet-1437	369	21	constant	constant	ADJ
admet-1437	369	22	median	median	ADJ
admet-1437	369	23	particle	particle	NOUN
admet-1437	369	24	size	size	NOUN
admet-1437	369	25	x50,3	x50,3	PROPN
admet-1437	369	26	.	.	PUNCT
admet-1437	370	1	the	the	DET
admet-1437	370	2	standard	standard	ADJ
admet-1437	370	3	deviation	deviation	NOUN
admet-1437	370	4	of	of	ADP
admet-1437	370	5	the	the	DET
admet-1437	370	6	log	log	NOUN
admet-1437	370	7	-	-	PUNCT
admet-1437	370	8	normal	normal	ADJ
admet-1437	370	9	distribution	distribution	NOUN
admet-1437	370	10	function	function	NOUN
admet-1437	370	11	(	(	PUNCT
admet-1437	370	12	σ	σ	NOUN
admet-1437	370	13	)	)	PUNCT
admet-1437	370	14	was	be	AUX
admet-1437	370	15	varied	varied	ADJ
admet-1437	370	16	from	from	ADP
admet-1437	370	17	the	the	DET
admet-1437	370	18	value	value	NOUN
admet-1437	370	19	of	of	ADP
admet-1437	370	20	0.51	0.51	NUM
admet-1437	370	21	,	,	PUNCT
admet-1437	370	22	determined	determine	VERB
admet-1437	370	23	by	by	ADP
admet-1437	370	24	fitting	fit	VERB
admet-1437	370	25	the	the	DET
admet-1437	370	26	log	log	NOUN
admet-1437	370	27	-	-	PUNCT
admet-1437	370	28	normal	normal	ADJ
admet-1437	370	29	distribution	distribution	NOUN
admet-1437	370	30	to	to	ADP
admet-1437	370	31	the	the	DET
admet-1437	370	32	experimental	experimental	ADJ
admet-1437	370	33	data	datum	NOUN
admet-1437	370	34	,	,	PUNCT
admet-1437	370	35	to	to	ADP
admet-1437	370	36	selected	select	VERB
admet-1437	370	37	values	value	NOUN
admet-1437	370	38	of	of	ADP
admet-1437	370	39	0.4	0.4	NUM
admet-1437	370	40	,	,	PUNCT
admet-1437	370	41	0.3	0.3	NUM
admet-1437	370	42	,	,	PUNCT
admet-1437	370	43	0.2	0.2	NUM
admet-1437	370	44	,	,	PUNCT
admet-1437	370	45	0.1	0.1	NUM
admet-1437	370	46	and	and	CCONJ
admet-1437	370	47	0.0001	0.0001	NUM
admet-1437	370	48	,	,	PUNCT
admet-1437	370	49	artificially	artificially	ADV
admet-1437	370	50	mimicking	mimic	VERB
admet-1437	370	51	narrower	narrow	ADJ
admet-1437	370	52	particle	particle	NOUN
admet-1437	370	53	size	size	NOUN
admet-1437	370	54	distributions	distribution	NOUN
admet-1437	370	55	and	and	CCONJ
admet-1437	370	56	eventually	eventually	ADV
admet-1437	370	57	a	a	DET
admet-1437	370	58	monodisperse	monodisperse	NOUN
admet-1437	370	59	system	system	NOUN
admet-1437	370	60	.	.	PUNCT
admet-1437	371	1	the	the	DET
admet-1437	371	2	obtained	obtain	VERB
admet-1437	371	3	calculated	calculate	VERB
admet-1437	371	4	results	result	NOUN
admet-1437	371	5	are	be	AUX
admet-1437	371	6	also	also	ADV
admet-1437	371	7	plotted	plot	VERB
admet-1437	371	8	in	in	ADP
admet-1437	371	9	figure	figure	NOUN
admet-1437	371	10	9	9	NUM
admet-1437	371	11	.	.	PUNCT
admet-1437	372	1	the	the	PRON
admet-1437	372	2	lower	low	ADJ
admet-1437	372	3	the	the	DET
admet-1437	372	4	standard	standard	ADJ
admet-1437	372	5	deviation	deviation	NOUN
admet-1437	372	6	,	,	PUNCT
admet-1437	372	7	the	the	DET
admet-1437	372	8	lower	low	ADJ
admet-1437	372	9	the	the	DET
admet-1437	372	10	amount	amount	NOUN
admet-1437	372	11	of	of	ADP
admet-1437	372	12	the	the	DET
admet-1437	372	13	fine	fine	ADJ
admet-1437	372	14	fraction	fraction	NOUN
admet-1437	372	15	,	,	PUNCT
admet-1437	372	16	which	which	PRON
admet-1437	372	17	is	be	AUX
admet-1437	372	18	relevant	relevant	ADJ
admet-1437	372	19	for	for	ADP
admet-1437	372	20	achieving	achieve	VERB
admet-1437	372	21	supersaturation	supersaturation	NOUN
admet-1437	372	22	.	.	PUNCT
admet-1437	373	1	hence	hence	ADV
admet-1437	373	2	,	,	PUNCT
admet-1437	373	3	the	the	DET
admet-1437	373	4	calculated	calculated	ADJ
admet-1437	373	5	apparent	apparent	ADJ
admet-1437	373	6	solubility	solubility	NOUN
admet-1437	373	7	decreases	decrease	VERB
admet-1437	373	8	for	for	ADP
admet-1437	373	9	decreasing	decrease	VERB
admet-1437	373	10	standard	standard	ADJ
admet-1437	373	11	deviations	deviation	NOUN
admet-1437	373	12	.	.	PUNCT
admet-1437	374	1	a	a	DET
admet-1437	374	2	more	more	ADV
admet-1437	374	3	pronounced	pronounce	VERB
admet-1437	374	4	plateau	plateau	NOUN
admet-1437	374	5	can	can	AUX
admet-1437	374	6	be	be	AUX
admet-1437	374	7	seen	see	VERB
admet-1437	374	8	when	when	SCONJ
admet-1437	374	9	the	the	DET
admet-1437	374	10	standard	standard	ADJ
admet-1437	374	11	deviation	deviation	NOUN
admet-1437	374	12	reaches	reach	VERB
admet-1437	374	13	the	the	DET
admet-1437	374	14	artificial	artificial	ADJ
admet-1437	374	15	value	value	NOUN
admet-1437	374	16	of	of	ADP
admet-1437	374	17	0.3	0.3	NUM
admet-1437	374	18	,	,	PUNCT
admet-1437	374	19	which	which	PRON
admet-1437	374	20	is	be	AUX
admet-1437	374	21	in	in	ADP
admet-1437	374	22	better	well	ADJ
admet-1437	374	23	agreement	agreement	NOUN
admet-1437	374	24	with	with	ADP
admet-1437	374	25	the	the	DET
admet-1437	374	26	experimental	experimental	ADJ
admet-1437	374	27	data	datum	NOUN
admet-1437	374	28	.	.	PUNCT
admet-1437	375	1	for	for	ADP
admet-1437	375	2	the	the	DET
admet-1437	375	3	monodisperse	monodisperse	NOUN
admet-1437	375	4	system	system	NOUN
admet-1437	375	5	(	(	PUNCT
admet-1437	375	6	σ	σ	NOUN
admet-1437	375	7	=	=	SYM
admet-1437	375	8	0.0001	0.0001	NUM
admet-1437	375	9	)	)	PUNCT
admet-1437	375	10	,	,	PUNCT
admet-1437	375	11	the	the	DET
admet-1437	375	12	apparent	apparent	ADJ
admet-1437	375	13	solubility	solubility	NOUN
admet-1437	375	14	first	first	ADV
admet-1437	375	15	decreases	decrease	VERB
admet-1437	375	16	with	with	ADP
admet-1437	375	17	increasing	increase	VERB
admet-1437	375	18	dose	dose	NOUN
admet-1437	375	19	number	number	NOUN
admet-1437	375	20	before	before	ADP
admet-1437	375	21	stabilizing	stabilize	VERB
admet-1437	375	22	at	at	ADP
admet-1437	375	23	a	a	DET
admet-1437	375	24	constant	constant	ADJ
admet-1437	375	25	value	value	NOUN
admet-1437	375	26	.	.	PUNCT
admet-1437	376	1	for	for	ADP
admet-1437	376	2	low	low	ADJ
admet-1437	376	3	dose	dose	NOUN
admet-1437	376	4	numbers	number	NOUN
admet-1437	376	5	,	,	PUNCT
admet-1437	376	6	the	the	DET
admet-1437	376	7	monodisperse	monodisperse	NOUN
admet-1437	376	8	particle	particle	NOUN
admet-1437	376	9	size	size	NOUN
admet-1437	376	10	notably	notably	ADV
admet-1437	376	11	decreases	decrease	VERB
admet-1437	376	12	during	during	ADP
admet-1437	376	13	the	the	DET
admet-1437	376	14	dissolution	dissolution	NOUN
admet-1437	376	15	process	process	NOUN
admet-1437	376	16	,	,	PUNCT
admet-1437	376	17	leading	lead	VERB
admet-1437	376	18	to	to	ADP
admet-1437	376	19	an	an	DET
admet-1437	376	20	increase	increase	NOUN
admet-1437	376	21	in	in	ADP
admet-1437	376	22	the	the	DET
admet-1437	376	23	apparent	apparent	ADJ
admet-1437	376	24	solubility	solubility	NOUN
admet-1437	376	25	.	.	PUNCT
admet-1437	377	1	with	with	ADP
admet-1437	377	2	increasing	increase	VERB
admet-1437	377	3	dose	dose	NOUN
admet-1437	377	4	number	number	NOUN
admet-1437	377	5	,	,	PUNCT
admet-1437	377	6	the	the	DET
admet-1437	377	7	decrease	decrease	NOUN
admet-1437	377	8	of	of	ADP
admet-1437	377	9	the	the	DET
admet-1437	377	10	particle	particle	NOUN
admet-1437	377	11	size	size	NOUN
admet-1437	377	12	and	and	CCONJ
admet-1437	377	13	admet	admet	PROPN
admet-1437	377	14	&	&	CCONJ
admet-1437	377	15	dmpk	dmpk	PROPN
admet-1437	377	16	10(4	10(4	NUM
admet-1437	377	17	)	)	PUNCT
admet-1437	377	18	(	(	PUNCT
admet-1437	377	19	2022	2022	NUM
admet-1437	377	20	)	)	PUNCT
admet-1437	377	21	253	253	NUM
admet-1437	377	22	-	-	SYM
admet-1437	377	23	287	287	NUM
admet-1437	377	24	modeling	modeling	NOUN
admet-1437	377	25	of	of	ADP
admet-1437	377	26	drug	drug	NOUN
admet-1437	377	27	nanocrystals	nanocrystal	NOUN
admet-1437	377	28	dissolution	dissolution	NOUN
admet-1437	377	29	doi	doi	PROPN
admet-1437	377	30	:	:	PUNCT
admet-1437	377	31	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	377	32	273	273	NUM
admet-1437	377	33	respective	respective	ADJ
admet-1437	377	34	increase	increase	NOUN
admet-1437	377	35	of	of	ADP
admet-1437	377	36	the	the	DET
admet-1437	377	37	apparent	apparent	ADJ
admet-1437	377	38	solubility	solubility	NOUN
admet-1437	377	39	becomes	become	VERB
admet-1437	377	40	smaller	small	ADJ
admet-1437	377	41	.	.	PUNCT
admet-1437	378	1	most	most	ADV
admet-1437	378	2	importantly	importantly	ADV
admet-1437	378	3	,	,	PUNCT
admet-1437	378	4	these	these	DET
admet-1437	378	5	observations	observation	NOUN
admet-1437	378	6	emphasize	emphasize	VERB
admet-1437	378	7	the	the	DET
admet-1437	378	8	high	high	ADJ
admet-1437	378	9	relevance	relevance	NOUN
admet-1437	378	10	of	of	ADP
admet-1437	378	11	the	the	DET
admet-1437	378	12	particle	particle	NOUN
admet-1437	378	13	size	size	NOUN
admet-1437	378	14	distribution	distribution	NOUN
admet-1437	378	15	as	as	ADP
admet-1437	378	16	an	an	DET
admet-1437	378	17	input	input	NOUN
admet-1437	378	18	parameter	parameter	NOUN
admet-1437	378	19	for	for	ADP
admet-1437	378	20	the	the	DET
admet-1437	378	21	calculation	calculation	NOUN
admet-1437	378	22	of	of	ADP
admet-1437	378	23	the	the	DET
admet-1437	378	24	apparent	apparent	ADJ
admet-1437	378	25	solubility	solubility	NOUN
admet-1437	378	26	.	.	PUNCT
admet-1437	379	1	an	an	DET
admet-1437	379	2	exact	exact	ADJ
admet-1437	379	3	characterization	characterization	NOUN
admet-1437	379	4	of	of	ADP
admet-1437	379	5	the	the	DET
admet-1437	379	6	drug	drug	NOUN
admet-1437	379	7	particle	particle	NOUN
admet-1437	379	8	size	size	NOUN
admet-1437	379	9	distribution	distribution	NOUN
admet-1437	379	10	,	,	PUNCT
admet-1437	379	11	especially	especially	ADV
admet-1437	379	12	its	its	PRON
admet-1437	379	13	fine	fine	ADJ
admet-1437	379	14	fraction	fraction	NOUN
admet-1437	379	15	,	,	PUNCT
admet-1437	379	16	is	be	AUX
admet-1437	379	17	therefore	therefore	ADV
admet-1437	379	18	paramount	paramount	ADJ
admet-1437	379	19	to	to	PART
admet-1437	379	20	model	model	VERB
admet-1437	379	21	its	its	PRON
admet-1437	379	22	dissolution	dissolution	ADJ
admet-1437	379	23	behavior	behavior	NOUN
admet-1437	379	24	more	more	ADV
admet-1437	379	25	accurately	accurately	ADV
admet-1437	379	26	.	.	PUNCT
admet-1437	380	1	for	for	ADP
admet-1437	380	2	this	this	DET
admet-1437	380	3	investigation	investigation	NOUN
admet-1437	380	4	,	,	PUNCT
admet-1437	380	5	the	the	DET
admet-1437	380	6	experimental	experimental	ADJ
admet-1437	380	7	data	datum	NOUN
admet-1437	380	8	from	from	ADP
admet-1437	380	9	pcs	pc	NOUN
admet-1437	380	10	measurements	measurement	NOUN
admet-1437	380	11	had	have	VERB
admet-1437	380	12	to	to	PART
admet-1437	380	13	be	be	AUX
admet-1437	380	14	further	far	ADV
admet-1437	380	15	processed	process	VERB
admet-1437	380	16	by	by	ADP
admet-1437	380	17	fitting	fit	VERB
admet-1437	380	18	them	they	PRON
admet-1437	380	19	to	to	ADP
admet-1437	380	20	a	a	DET
admet-1437	380	21	log	log	NOUN
admet-1437	380	22	-	-	PUNCT
admet-1437	380	23	normal	normal	ADJ
admet-1437	380	24	distribution	distribution	NOUN
admet-1437	380	25	function	function	NOUN
admet-1437	380	26	and	and	CCONJ
admet-1437	380	27	extrapolation	extrapolation	NOUN
admet-1437	380	28	below	below	ADP
admet-1437	380	29	x10,3	x10,3	PROPN
admet-1437	380	30	introducing	introduce	VERB
admet-1437	380	31	significant	significant	ADJ
admet-1437	380	32	uncertainty	uncertainty	NOUN
admet-1437	380	33	.	.	PUNCT
admet-1437	381	1	in	in	ADP
admet-1437	381	2	fact	fact	NOUN
admet-1437	381	3	,	,	PUNCT
admet-1437	381	4	it	it	PRON
admet-1437	381	5	can	can	AUX
admet-1437	381	6	be	be	AUX
admet-1437	381	7	seen	see	VERB
admet-1437	381	8	in	in	ADP
admet-1437	381	9	table	table	NOUN
admet-1437	381	10	2	2	NUM
admet-1437	381	11	that	that	PRON
admet-1437	381	12	already	already	ADV
admet-1437	381	13	the	the	DET
admet-1437	381	14	x10,3	x10,3	PROPN
admet-1437	381	15	value	value	NOUN
admet-1437	381	16	is	be	AUX
admet-1437	381	17	systematically	systematically	ADV
admet-1437	381	18	underpredicted	underpredicte	VERB
admet-1437	381	19	by	by	ADP
admet-1437	381	20	the	the	DET
admet-1437	381	21	fitted	fit	VERB
admet-1437	381	22	log	log	NOUN
admet-1437	381	23	-	-	PUNCT
admet-1437	381	24	normal	normal	ADJ
admet-1437	381	25	distribution	distribution	NOUN
admet-1437	381	26	function	function	NOUN
admet-1437	381	27	.	.	PUNCT
admet-1437	382	1	this	this	PRON
admet-1437	382	2	leads	lead	VERB
admet-1437	382	3	to	to	ADP
admet-1437	382	4	an	an	DET
admet-1437	382	5	overestimation	overestimation	NOUN
admet-1437	382	6	of	of	ADP
admet-1437	382	7	the	the	DET
admet-1437	382	8	fine	fine	ADJ
admet-1437	382	9	fraction	fraction	NOUN
admet-1437	382	10	in	in	ADP
admet-1437	382	11	the	the	DET
admet-1437	382	12	numerical	numerical	ADJ
admet-1437	382	13	calculation	calculation	NOUN
admet-1437	382	14	,	,	PUNCT
admet-1437	382	15	which	which	PRON
admet-1437	382	16	leads	lead	VERB
admet-1437	382	17	to	to	ADP
admet-1437	382	18	an	an	DET
admet-1437	382	19	overestimation	overestimation	NOUN
admet-1437	382	20	of	of	ADP
admet-1437	382	21	the	the	DET
admet-1437	382	22	calculated	calculate	VERB
admet-1437	382	23	apparent	apparent	ADJ
admet-1437	382	24	solubility	solubility	NOUN
admet-1437	382	25	,	,	PUNCT
admet-1437	382	26	especially	especially	ADV
admet-1437	382	27	for	for	ADP
admet-1437	382	28	high	high	ADJ
admet-1437	382	29	do	do	AUX
admet-1437	382	30	values	value	NOUN
admet-1437	382	31	.	.	PUNCT
admet-1437	383	1	furthermore	furthermore	ADV
admet-1437	383	2	,	,	PUNCT
admet-1437	383	3	the	the	DET
admet-1437	383	4	assumption	assumption	NOUN
admet-1437	383	5	of	of	ADP
admet-1437	383	6	a	a	DET
admet-1437	383	7	log	log	NOUN
admet-1437	383	8	-	-	PUNCT
admet-1437	383	9	normal	normal	ADJ
admet-1437	383	10	shaped	shape	VERB
admet-1437	383	11	distribution	distribution	NOUN
admet-1437	383	12	function	function	NOUN
admet-1437	383	13	might	might	AUX
admet-1437	383	14	not	not	PART
admet-1437	383	15	be	be	AUX
admet-1437	383	16	ideal	ideal	ADJ
admet-1437	383	17	for	for	ADP
admet-1437	383	18	the	the	DET
admet-1437	383	19	nanocrystal	nanocrystal	ADJ
admet-1437	383	20	systems	system	NOUN
admet-1437	383	21	and	and	CCONJ
admet-1437	383	22	fails	fail	VERB
admet-1437	383	23	to	to	PART
admet-1437	383	24	accurately	accurately	ADV
admet-1437	383	25	describe	describe	VERB
admet-1437	383	26	the	the	DET
admet-1437	383	27	lower	low	ADJ
admet-1437	383	28	end	end	NOUN
admet-1437	383	29	of	of	ADP
admet-1437	383	30	the	the	DET
admet-1437	383	31	true	true	ADJ
admet-1437	383	32	particle	particle	NOUN
admet-1437	383	33	size	size	NOUN
admet-1437	383	34	distribution	distribution	NOUN
admet-1437	383	35	.	.	PUNCT
admet-1437	384	1	the	the	DET
admet-1437	384	2	accuracy	accuracy	NOUN
admet-1437	384	3	of	of	ADP
admet-1437	384	4	the	the	DET
admet-1437	384	5	numerical	numerical	ADJ
admet-1437	384	6	model	model	NOUN
admet-1437	384	7	and	and	CCONJ
admet-1437	384	8	its	its	PRON
admet-1437	384	9	capability	capability	NOUN
admet-1437	384	10	to	to	PART
admet-1437	384	11	describe	describe	VERB
admet-1437	384	12	the	the	DET
admet-1437	384	13	dependence	dependence	NOUN
admet-1437	384	14	of	of	ADP
admet-1437	384	15	the	the	DET
admet-1437	384	16	apparent	apparent	ADJ
admet-1437	384	17	solubility	solubility	NOUN
admet-1437	384	18	on	on	ADP
admet-1437	384	19	do	do	NOUN
admet-1437	384	20	could	could	AUX
admet-1437	384	21	be	be	AUX
admet-1437	384	22	further	far	ADV
admet-1437	384	23	increased	increase	VERB
admet-1437	384	24	by	by	ADP
admet-1437	384	25	improving	improve	VERB
admet-1437	384	26	the	the	DET
admet-1437	384	27	quality	quality	NOUN
admet-1437	384	28	of	of	ADP
admet-1437	384	29	the	the	DET
admet-1437	384	30	input	input	NOUN
admet-1437	384	31	data	datum	NOUN
admet-1437	384	32	.	.	PUNCT
admet-1437	385	1	analytical	analytical	ADJ
admet-1437	385	2	centrifugation	centrifugation	NOUN
admet-1437	385	3	coupled	couple	VERB
admet-1437	385	4	with	with	ADP
admet-1437	385	5	appropriate	appropriate	ADJ
admet-1437	385	6	interpolation	interpolation	NOUN
admet-1437	385	7	for	for	ADP
admet-1437	385	8	sufficient	sufficient	ADJ
admet-1437	385	9	discretization	discretization	NOUN
admet-1437	385	10	might	might	AUX
admet-1437	385	11	be	be	AUX
admet-1437	385	12	a	a	DET
admet-1437	385	13	better	well	ADV
admet-1437	385	14	-	-	PUNCT
admet-1437	385	15	suited	suit	VERB
admet-1437	385	16	method	method	NOUN
admet-1437	385	17	to	to	PART
admet-1437	385	18	describe	describe	VERB
admet-1437	385	19	the	the	DET
admet-1437	385	20	particle	particle	NOUN
admet-1437	385	21	size	size	NOUN
admet-1437	385	22	distributions	distribution	NOUN
admet-1437	385	23	of	of	ADP
admet-1437	385	24	nanocrystal	nanocrystal	ADJ
admet-1437	385	25	systems	system	NOUN
admet-1437	385	26	.	.	PUNCT
admet-1437	386	1	figure	figure	NOUN
admet-1437	386	2	9	9	NUM
admet-1437	386	3	.	.	PUNCT
admet-1437	386	4	experimentally	experimentally	ADV
admet-1437	386	5	determined	determine	VERB
admet-1437	386	6	apparent	apparent	ADJ
admet-1437	386	7	solubility	solubility	NOUN
admet-1437	386	8	(	(	PUNCT
admet-1437	386	9	sapp	sapp	PROPN
admet-1437	386	10	,	,	PUNCT
admet-1437	386	11	exp	exp	NOUN
admet-1437	386	12	)	)	PUNCT
admet-1437	386	13	for	for	ADP
admet-1437	386	14	a	a	DET
admet-1437	386	15	polydisperse	polydisperse	NOUN
admet-1437	386	16	particle	particle	NOUN
admet-1437	386	17	size	size	NOUN
admet-1437	386	18	distribution	distribution	NOUN
admet-1437	386	19	(	(	PUNCT
admet-1437	386	20	particle	particle	NOUN
admet-1437	386	21	size	size	NOUN
admet-1437	386	22	x50,3	x50,3	PUNCT
admet-1437	387	1	=	=	SYM
admet-1437	387	2	111	111	NUM
admet-1437	387	3	nm	nm	NOUN
admet-1437	387	4	)	)	PUNCT
admet-1437	387	5	with	with	ADP
admet-1437	387	6	different	different	ADJ
admet-1437	387	7	ratio	ratio	NOUN
admet-1437	387	8	of	of	ADP
admet-1437	387	9	available	available	ADJ
admet-1437	387	10	solids	solid	NOUN
admet-1437	387	11	to	to	ADP
admet-1437	387	12	thermodynamically	thermodynamically	ADV
admet-1437	387	13	soluble	soluble	ADJ
admet-1437	387	14	amount	amount	NOUN
admet-1437	387	15	(	(	PUNCT
admet-1437	387	16	do	do	NOUN
admet-1437	387	17	)	)	PUNCT
admet-1437	387	18	vs	vs	ADP
admet-1437	387	19	calculated	calculate	VERB
admet-1437	387	20	apparent	apparent	ADJ
admet-1437	387	21	solubility	solubility	NOUN
admet-1437	387	22	(	(	PUNCT
admet-1437	387	23	sapp	sapp	PROPN
admet-1437	387	24	,	,	PUNCT
admet-1437	387	25	th	th	X
admet-1437	387	26	)	)	PUNCT
admet-1437	387	27	for	for	ADP
admet-1437	387	28	polydisperse	polydisperse	NOUN
admet-1437	387	29	particle	particle	NOUN
admet-1437	387	30	size	size	NOUN
admet-1437	387	31	distribution	distribution	NOUN
admet-1437	387	32	with	with	ADP
admet-1437	387	33	median	median	ADJ
admet-1437	387	34	particle	particle	NOUN
admet-1437	387	35	size	size	NOUN
admet-1437	387	36	x50,3	x50,3	PUNCT
admet-1437	388	1	=	=	SYM
admet-1437	388	2	111	111	NUM
admet-1437	388	3	nm	nm	NOUN
admet-1437	388	4	with	with	ADP
admet-1437	388	5	a	a	DET
admet-1437	388	6	fitted	fit	VERB
admet-1437	388	7	standard	standard	ADJ
admet-1437	388	8	deviation	deviation	NOUN
admet-1437	388	9	of	of	ADP
admet-1437	388	10	the	the	DET
admet-1437	388	11	particle	particle	NOUN
admet-1437	388	12	size	size	NOUN
admet-1437	388	13	distribution	distribution	NOUN
admet-1437	388	14	(	(	PUNCT
admet-1437	388	15	σ	σ	NOUN
admet-1437	388	16	)	)	PUNCT
admet-1437	388	17	of	of	ADP
admet-1437	388	18	0.51	0.51	NUM
admet-1437	388	19	and	and	CCONJ
admet-1437	388	20	selected	select	VERB
admet-1437	388	21	standard	standard	ADJ
admet-1437	388	22	deviations	deviation	NOUN
admet-1437	388	23	of	of	ADP
admet-1437	388	24	0.4	0.4	NUM
admet-1437	388	25	,	,	PUNCT
admet-1437	388	26	0.3	0.3	NUM
admet-1437	388	27	,	,	PUNCT
admet-1437	388	28	0.2	0.2	NUM
admet-1437	388	29	,	,	PUNCT
admet-1437	388	30	0.1	0.1	NUM
admet-1437	388	31	and	and	CCONJ
admet-1437	388	32	0.0001	0.0001	NUM
admet-1437	388	33	with	with	ADP
admet-1437	388	34	interfacial	interfacial	ADJ
admet-1437	388	35	energy	energy	NOUN
admet-1437	388	36	30	30	NUM
admet-1437	388	37	mj	mj	NOUN
admet-1437	388	38	/	/	SYM
admet-1437	388	39	m2	m2	PROPN
admet-1437	388	40	and	and	CCONJ
admet-1437	388	41	different	different	ADJ
admet-1437	388	42	ratio	ratio	NOUN
admet-1437	388	43	of	of	ADP
admet-1437	388	44	available	available	ADJ
admet-1437	388	45	solids	solid	NOUN
admet-1437	388	46	to	to	ADP
admet-1437	388	47	thermodynamically	thermodynamically	ADV
admet-1437	388	48	soluble	soluble	ADJ
admet-1437	388	49	amount	amount	NOUN
admet-1437	388	50	(	(	PUNCT
admet-1437	388	51	do	do	AUX
admet-1437	388	52	)	)	PUNCT
admet-1437	388	53	using	use	VERB
admet-1437	388	54	numerical	numerical	ADJ
admet-1437	388	55	calculation	calculation	NOUN
admet-1437	388	56	.	.	PUNCT
admet-1437	389	1	nevertheless	nevertheless	ADV
admet-1437	389	2	,	,	PUNCT
admet-1437	389	3	for	for	ADP
admet-1437	389	4	this	this	DET
admet-1437	389	5	study	study	NOUN
admet-1437	389	6	,	,	PUNCT
admet-1437	389	7	the	the	DET
admet-1437	389	8	fitted	fit	VERB
admet-1437	389	9	particle	particle	NOUN
admet-1437	389	10	size	size	NOUN
admet-1437	389	11	distributions	distribution	NOUN
admet-1437	389	12	,	,	PUNCT
admet-1437	389	13	as	as	SCONJ
admet-1437	389	14	reported	report	VERB
admet-1437	389	15	in	in	ADP
admet-1437	389	16	table	table	NOUN
admet-1437	389	17	2	2	NUM
admet-1437	389	18	,	,	PUNCT
admet-1437	389	19	are	be	AUX
admet-1437	389	20	used	use	VERB
admet-1437	389	21	for	for	ADP
admet-1437	389	22	further	further	ADJ
admet-1437	389	23	calculations	calculation	NOUN
admet-1437	389	24	without	without	ADP
admet-1437	389	25	any	any	DET
admet-1437	389	26	artificial	artificial	ADJ
admet-1437	389	27	adjustment	adjustment	NOUN
admet-1437	389	28	.	.	PUNCT
admet-1437	390	1	a	a	DET
admet-1437	390	2	reasonable	reasonable	ADJ
admet-1437	390	3	error	error	NOUN
admet-1437	390	4	of	of	ADP
admet-1437	390	5	<	<	X
admet-1437	390	6	10	10	NUM
admet-1437	390	7	%	%	NOUN
admet-1437	390	8	between	between	ADP
admet-1437	390	9	experimental	experimental	ADJ
admet-1437	390	10	and	and	CCONJ
admet-1437	390	11	calculated	calculate	VERB
admet-1437	390	12	apparent	apparent	ADJ
admet-1437	390	13	solubility	solubility	NOUN
admet-1437	390	14	is	be	AUX
admet-1437	390	15	found	find	VERB
admet-1437	390	16	for	for	ADP
admet-1437	390	17	do	do	AUX
admet-1437	390	18	<	<	X
admet-1437	390	19	18	18	NUM
admet-1437	390	20	,	,	PUNCT
admet-1437	390	21	which	which	PRON
admet-1437	390	22	is	be	AUX
admet-1437	390	23	considered	consider	VERB
admet-1437	390	24	appropriate	appropriate	ADJ
admet-1437	390	25	for	for	ADP
admet-1437	390	26	further	further	ADJ
admet-1437	390	27	calculations	calculation	NOUN
admet-1437	390	28	.	.	PUNCT
admet-1437	391	1	for	for	ADP
admet-1437	391	2	most	most	ADJ
admet-1437	391	3	calculations	calculation	NOUN
admet-1437	391	4	carried	carry	VERB
admet-1437	391	5	out	out	ADP
admet-1437	391	6	in	in	ADP
admet-1437	391	7	this	this	DET
admet-1437	391	8	study	study	NOUN
admet-1437	391	9	,	,	PUNCT
admet-1437	391	10	do	do	VERB
admet-1437	391	11	<	<	X
admet-1437	391	12	18	18	NUM
admet-1437	391	13	is	be	AUX
admet-1437	391	14	fulfilled	fulfil	VERB
admet-1437	391	15	.	.	PUNCT
admet-1437	392	1	since	since	SCONJ
admet-1437	392	2	a	a	DET
admet-1437	392	3	true	true	ADJ
admet-1437	392	4	supersaturation	supersaturation	NOUN
admet-1437	392	5	is	be	AUX
admet-1437	392	6	obtained	obtain	VERB
admet-1437	392	7	during	during	ADP
admet-1437	392	8	the	the	DET
admet-1437	392	9	dissolution	dissolution	NOUN
admet-1437	392	10	of	of	ADP
admet-1437	392	11	ultrafine	ultrafine	NOUN
admet-1437	392	12	drug	drug	NOUN
admet-1437	392	13	nanocrystal	nanocrystal	ADJ
admet-1437	392	14	particle	particle	NOUN
admet-1437	392	15	size	size	NOUN
admet-1437	392	16	distributions	distribution	NOUN
admet-1437	392	17	for	for	ADP
admet-1437	392	18	a	a	DET
admet-1437	392	19	solid	solid	ADJ
admet-1437	392	20	drug	drug	NOUN
admet-1437	392	21	amount	amount	NOUN
admet-1437	392	22	at	at	ADP
admet-1437	392	23	do	do	PROPN
admet-1437	392	24	>	>	PROPN
admet-1437	392	25	1	1	NUM
admet-1437	392	26	,	,	PUNCT
admet-1437	392	27	subsequent	subsequent	ADJ
admet-1437	392	28	precipitation	precipitation	NOUN
admet-1437	392	29	/	/	SYM
admet-1437	392	30	crystallization	crystallization	NOUN
admet-1437	392	31	and	and	CCONJ
admet-1437	392	32	decrease	decrease	NOUN
admet-1437	392	33	of	of	ADP
admet-1437	392	34	the	the	DET
admet-1437	392	35	apparent	apparent	ADJ
admet-1437	392	36	solubility	solubility	NOUN
admet-1437	392	37	over	over	ADP
admet-1437	392	38	time	time	NOUN
admet-1437	392	39	to	to	ADP
admet-1437	392	40	the	the	DET
admet-1437	392	41	level	level	NOUN
admet-1437	392	42	of	of	ADP
admet-1437	392	43	the	the	DET
admet-1437	392	44	thermodynamic	thermodynamic	ADJ
admet-1437	392	45	solubility	solubility	NOUN
admet-1437	392	46	by	by	ADP
admet-1437	392	47	way	way	NOUN
admet-1437	392	48	of	of	ADP
admet-1437	392	49	ostwald	ostwald	NOUN
admet-1437	392	50	ripening	ripening	NOUN
admet-1437	392	51	would	would	AUX
admet-1437	392	52	be	be	AUX
admet-1437	392	53	a	a	DET
admet-1437	392	54	matter	matter	NOUN
admet-1437	392	55	of	of	ADP
admet-1437	392	56	concern	concern	NOUN
admet-1437	392	57	.	.	PUNCT
admet-1437	393	1	for	for	ADP
admet-1437	393	2	this	this	DET
admet-1437	393	3	drug	drug	NOUN
admet-1437	393	4	-	-	PUNCT
admet-1437	393	5	stabilizer	stabilizer	NOUN
admet-1437	393	6	system	system	NOUN
admet-1437	393	7	,	,	PUNCT
admet-1437	393	8	however	however	ADV
admet-1437	393	9	,	,	PUNCT
admet-1437	393	10	stability	stability	NOUN
admet-1437	393	11	studies	study	NOUN
admet-1437	393	12	with	with	ADP
admet-1437	393	13	selected	select	VERB
admet-1437	393	14	drug	drug	NOUN
admet-1437	393	15	nanocrystal	nanocrystal	ADJ
admet-1437	393	16	suspensions	suspension	NOUN
admet-1437	393	17	have	have	AUX
admet-1437	393	18	shown	show	VERB
admet-1437	393	19	good	good	ADJ
admet-1437	393	20	stability	stability	NOUN
admet-1437	393	21	on	on	ADP
admet-1437	393	22	the	the	DET
admet-1437	393	23	level	level	NOUN
admet-1437	393	24	of	of	ADP
admet-1437	393	25	supersaturation	supersaturation	NOUN
admet-1437	393	26	at	at	ADP
admet-1437	393	27	22	22	NUM
admet-1437	393	28	°	°	NOUN
admet-1437	393	29	c	c	NOUN
admet-1437	393	30	over	over	ADP
admet-1437	393	31	several	several	ADJ
admet-1437	393	32	weeks	week	NOUN
admet-1437	393	33	with	with	ADP
admet-1437	393	34	a	a	DET
admet-1437	393	35	decrease	decrease	NOUN
admet-1437	393	36	of	of	ADP
admet-1437	393	37	the	the	DET
admet-1437	393	38	measured	measure	VERB
admet-1437	393	39	apparent	apparent	ADJ
admet-1437	393	40	solubility	solubility	NOUN
admet-1437	393	41	of	of	ADP
admet-1437	393	42	less	less	ADJ
admet-1437	393	43	than	than	ADP
admet-1437	393	44	10	10	NUM
admet-1437	393	45	%	%	NOUN
admet-1437	393	46	.	.	PUNCT
admet-1437	394	1	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	NOUN
admet-1437	394	2	bonhoeffer	bonhoeffer	PROPN
admet-1437	394	3	et	et	PROPN
admet-1437	394	4	al	al	PROPN
admet-1437	394	5	.	.	PROPN
admet-1437	394	6	admet	admet	PROPN
admet-1437	394	7	&	&	CCONJ
admet-1437	394	8	dmpk	dmpk	PROPN
admet-1437	394	9	10(4	10(4	NUM
admet-1437	394	10	)	)	PUNCT
admet-1437	394	11	(	(	PUNCT
admet-1437	394	12	2022	2022	NUM
admet-1437	394	13	)	)	PUNCT
admet-1437	394	14	253	253	NUM
admet-1437	394	15	-	-	SYM
admet-1437	394	16	287	287	NUM
admet-1437	394	17	274	274	NUM
admet-1437	394	18	modeling	modeling	NOUN
admet-1437	394	19	results	result	NOUN
admet-1437	394	20	for	for	ADP
admet-1437	394	21	in	in	ADP
admet-1437	394	22	vivo	vivo	ADJ
admet-1437	394	23	dissolution	dissolution	NOUN
admet-1437	394	24	human	human	ADJ
admet-1437	394	25	gastrointestinal	gastrointestinal	ADJ
admet-1437	394	26	physiology	physiology	NOUN
admet-1437	394	27	is	be	AUX
admet-1437	394	28	a	a	DET
admet-1437	394	29	complex	complex	ADJ
admet-1437	394	30	interplay	interplay	NOUN
admet-1437	394	31	of	of	ADP
admet-1437	394	32	different	different	ADJ
admet-1437	394	33	factors	factor	NOUN
admet-1437	394	34	.	.	PUNCT
admet-1437	395	1	recent	recent	ADJ
admet-1437	395	2	advances	advance	NOUN
admet-1437	395	3	highlighted	highlight	VERB
admet-1437	395	4	the	the	DET
admet-1437	395	5	dynamics	dynamic	NOUN
admet-1437	395	6	within	within	ADP
admet-1437	395	7	the	the	DET
admet-1437	395	8	gastrointestinal	gastrointestinal	ADJ
admet-1437	395	9	tract	tract	NOUN
admet-1437	395	10	and	and	CCONJ
admet-1437	395	11	the	the	DET
admet-1437	395	12	relevance	relevance	NOUN
admet-1437	395	13	of	of	ADP
admet-1437	395	14	the	the	DET
admet-1437	395	15	parameters	parameter	NOUN
admet-1437	395	16	fluid	fluid	ADJ
admet-1437	395	17	volume	volume	NOUN
admet-1437	395	18	and	and	CCONJ
admet-1437	395	19	ph	ph	NOUN
admet-1437	395	20	,	,	PUNCT
admet-1437	395	21	and	and	CCONJ
admet-1437	395	22	their	their	PRON
admet-1437	395	23	related	related	ADJ
admet-1437	395	24	variabilities	variability	NOUN
admet-1437	395	25	[	[	X
admet-1437	395	26	84	84	NUM
admet-1437	395	27	-	-	SYM
admet-1437	395	28	86	86	NUM
admet-1437	395	29	]	]	PUNCT
admet-1437	395	30	.	.	PUNCT
admet-1437	396	1	modeling	modeling	NOUN
admet-1437	396	2	approaches	approach	NOUN
admet-1437	396	3	are	be	AUX
admet-1437	396	4	valuable	valuable	ADJ
admet-1437	396	5	and	and	CCONJ
admet-1437	396	6	efficient	efficient	ADJ
admet-1437	396	7	to	to	PART
admet-1437	396	8	experiment	experiment	VERB
admet-1437	396	9	in	in	ADP
admet-1437	396	10	silico	silico	NOUN
admet-1437	396	11	the	the	DET
admet-1437	396	12	complexity	complexity	NOUN
admet-1437	396	13	of	of	ADP
admet-1437	396	14	different	different	ADJ
admet-1437	396	15	scenarios	scenario	NOUN
admet-1437	396	16	of	of	ADP
admet-1437	396	17	formulation	formulation	NOUN
admet-1437	396	18	-	-	PUNCT
admet-1437	396	19	gastrointestinal	gastrointestinal	ADJ
admet-1437	396	20	parameter	parameter	NOUN
admet-1437	396	21	combinations	combination	NOUN
admet-1437	396	22	,	,	PUNCT
admet-1437	396	23	provided	provide	VERB
admet-1437	396	24	the	the	DET
admet-1437	396	25	validity	validity	NOUN
admet-1437	396	26	of	of	ADP
admet-1437	396	27	the	the	DET
admet-1437	396	28	model	model	NOUN
admet-1437	396	29	.	.	PUNCT
admet-1437	397	1	different	different	ADJ
admet-1437	397	2	formulations	formulation	NOUN
admet-1437	397	3	and	and	CCONJ
admet-1437	397	4	in	in	ADP
admet-1437	397	5	vivo	vivo	ADJ
admet-1437	397	6	scenarios	scenario	NOUN
admet-1437	397	7	were	be	AUX
admet-1437	397	8	selected	select	VERB
admet-1437	397	9	to	to	PART
admet-1437	397	10	calculate	calculate	VERB
admet-1437	397	11	the	the	DET
admet-1437	397	12	dissolution	dissolution	ADJ
admet-1437	397	13	behavior	behavior	NOUN
admet-1437	397	14	using	use	VERB
admet-1437	397	15	the	the	DET
admet-1437	397	16	established	establish	VERB
admet-1437	397	17	numerical	numerical	ADJ
admet-1437	397	18	model	model	NOUN
admet-1437	397	19	,	,	PUNCT
admet-1437	397	20	representing	represent	VERB
admet-1437	397	21	a	a	DET
admet-1437	397	22	simplistic	simplistic	ADJ
admet-1437	397	23	,	,	PUNCT
admet-1437	397	24	closed	closed	ADJ
admet-1437	397	25	system	system	NOUN
admet-1437	397	26	neglecting	neglect	VERB
admet-1437	397	27	any	any	ADV
admet-1437	397	28	further	far	ADV
admet-1437	397	29	in	in	ADP
admet-1437	397	30	vivo	vivo	ADJ
admet-1437	397	31	relevant	relevant	ADJ
admet-1437	397	32	process	process	NOUN
admet-1437	397	33	,	,	PUNCT
admet-1437	397	34	i.e.	i.e.	X
admet-1437	397	35	,	,	PUNCT
admet-1437	397	36	the	the	DET
admet-1437	397	37	evolution	evolution	NOUN
admet-1437	397	38	of	of	ADP
admet-1437	397	39	fluid	fluid	ADJ
admet-1437	397	40	parameters	parameter	NOUN
admet-1437	397	41	and	and	CCONJ
admet-1437	397	42	permeation	permeation	NOUN
admet-1437	397	43	of	of	ADP
admet-1437	397	44	the	the	DET
admet-1437	397	45	drug	drug	NOUN
admet-1437	397	46	.	.	PUNCT
admet-1437	398	1	a	a	DET
admet-1437	398	2	fluid	fluid	NOUN
admet-1437	398	3	of	of	ADP
admet-1437	398	4	ph	ph	ADJ
admet-1437	398	5	2	2	NUM
admet-1437	398	6	and	and	CCONJ
admet-1437	398	7	a	a	DET
admet-1437	398	8	minimum	minimum	ADJ
admet-1437	398	9	volume	volume	NOUN
admet-1437	398	10	of	of	ADP
admet-1437	398	11	20	20	NUM
admet-1437	398	12	ml	ml	NOUN
admet-1437	398	13	and	and	CCONJ
admet-1437	398	14	a	a	DET
admet-1437	398	15	maximum	maximum	ADJ
admet-1437	398	16	volume	volume	NOUN
admet-1437	398	17	of	of	ADP
admet-1437	398	18	250	250	NUM
admet-1437	398	19	ml	ml	NOUN
admet-1437	398	20	were	be	AUX
admet-1437	398	21	selected	select	VERB
admet-1437	398	22	to	to	PART
admet-1437	398	23	represent	represent	VERB
admet-1437	398	24	the	the	DET
admet-1437	398	25	variability	variability	NOUN
admet-1437	398	26	of	of	ADP
admet-1437	398	27	the	the	DET
admet-1437	398	28	fasted	fasted	ADJ
admet-1437	398	29	state	state	NOUN
admet-1437	398	30	of	of	ADP
admet-1437	398	31	the	the	DET
admet-1437	398	32	gastrointestinal	gastrointestinal	ADJ
admet-1437	398	33	tract	tract	NOUN
admet-1437	399	1	[	[	X
admet-1437	399	2	84	84	NUM
admet-1437	399	3	-	-	SYM
admet-1437	399	4	86	86	NUM
admet-1437	399	5	]	]	PUNCT
admet-1437	399	6	.	.	PUNCT
admet-1437	400	1	a	a	DET
admet-1437	400	2	fluid	fluid	NOUN
admet-1437	400	3	of	of	ADP
admet-1437	400	4	ph	ph	ADJ
admet-1437	400	5	3	3	NUM
admet-1437	400	6	and	and	CCONJ
admet-1437	400	7	4.5	4.5	NUM
admet-1437	400	8	and	and	CCONJ
admet-1437	400	9	a	a	DET
admet-1437	400	10	minimum	minimum	ADJ
admet-1437	400	11	volume	volume	NOUN
admet-1437	400	12	of	of	ADP
admet-1437	400	13	250	250	NUM
admet-1437	400	14	ml	ml	NOUN
admet-1437	400	15	and	and	CCONJ
admet-1437	400	16	a	a	DET
admet-1437	400	17	maximum	maximum	ADJ
admet-1437	400	18	volume	volume	NOUN
admet-1437	400	19	of	of	ADP
admet-1437	400	20	900	900	NUM
admet-1437	400	21	ml	ml	NOUN
admet-1437	400	22	were	be	AUX
admet-1437	400	23	selected	select	VERB
admet-1437	400	24	to	to	PART
admet-1437	400	25	represent	represent	VERB
admet-1437	400	26	the	the	DET
admet-1437	400	27	variability	variability	NOUN
admet-1437	400	28	of	of	ADP
admet-1437	400	29	the	the	DET
admet-1437	400	30	fedstate	fedstate	NOUN
admet-1437	400	31	of	of	ADP
admet-1437	400	32	the	the	DET
admet-1437	400	33	gastrointestinal	gastrointestinal	ADJ
admet-1437	400	34	tract	tract	NOUN
admet-1437	401	1	[	[	X
admet-1437	401	2	84	84	NUM
admet-1437	401	3	-	-	SYM
admet-1437	401	4	86	86	NUM
admet-1437	401	5	]	]	PUNCT
admet-1437	401	6	.	.	PUNCT
admet-1437	402	1	the	the	DET
admet-1437	402	2	formulation	formulation	NOUN
admet-1437	402	3	parameters	parameter	NOUN
admet-1437	402	4	solid	solid	ADJ
admet-1437	402	5	drug	drug	NOUN
admet-1437	402	6	amount	amount	NOUN
admet-1437	402	7	,	,	PUNCT
admet-1437	402	8	respectively	respectively	ADV
admet-1437	402	9	dose	dose	NOUN
admet-1437	402	10	strength	strength	NOUN
admet-1437	402	11	and	and	CCONJ
admet-1437	402	12	nanocrystal	nanocrystal	ADJ
admet-1437	402	13	particle	particle	NOUN
admet-1437	402	14	size	size	NOUN
admet-1437	402	15	distribution	distribution	NOUN
admet-1437	402	16	were	be	AUX
admet-1437	402	17	investigated	investigate	VERB
admet-1437	402	18	,	,	PUNCT
admet-1437	402	19	which	which	PRON
admet-1437	402	20	represent	represent	VERB
admet-1437	402	21	typical	typical	ADJ
admet-1437	402	22	configurable	configurable	ADJ
admet-1437	402	23	variables	variable	NOUN
admet-1437	402	24	in	in	ADP
admet-1437	402	25	drug	drug	NOUN
admet-1437	402	26	development	development	NOUN
admet-1437	402	27	.	.	PUNCT
admet-1437	403	1	the	the	DET
admet-1437	403	2	solid	solid	ADJ
admet-1437	403	3	drug	drug	NOUN
admet-1437	403	4	amount	amount	NOUN
admet-1437	403	5	,	,	PUNCT
admet-1437	403	6	respectively	respectively	ADV
admet-1437	403	7	dose	dose	NOUN
admet-1437	403	8	strength	strength	NOUN
admet-1437	403	9	,	,	PUNCT
admet-1437	403	10	was	be	AUX
admet-1437	403	11	selected	select	VERB
admet-1437	403	12	to	to	ADP
admet-1437	403	13	25	25	NUM
admet-1437	403	14	and	and	CCONJ
admet-1437	403	15	100	100	NUM
admet-1437	403	16	mg	mg	NOUN
admet-1437	403	17	.	.	PUNCT
admet-1437	404	1	different	different	ADJ
admet-1437	404	2	drug	drug	NOUN
admet-1437	404	3	nanocrystal	nanocrystal	ADJ
admet-1437	404	4	particle	particle	NOUN
admet-1437	404	5	size	size	NOUN
admet-1437	404	6	distributions	distribution	NOUN
admet-1437	404	7	were	be	AUX
admet-1437	404	8	selected	select	VERB
admet-1437	404	9	according	accord	VERB
admet-1437	404	10	to	to	ADP
admet-1437	404	11	experiments	experiment	NOUN
admet-1437	404	12	no	no	INTJ
admet-1437	404	13	.	.	NOUN
admet-1437	404	14	1	1	NUM
admet-1437	404	15	,	,	PUNCT
admet-1437	404	16	2	2	NUM
admet-1437	404	17	,	,	PUNCT
admet-1437	404	18	5	5	NUM
admet-1437	404	19	and	and	CCONJ
admet-1437	404	20	8	8	NUM
admet-1437	404	21	in	in	ADP
admet-1437	404	22	table	table	NOUN
admet-1437	404	23	2	2	NUM
admet-1437	404	24	.	.	PUNCT
admet-1437	404	25	figure	figure	NOUN
admet-1437	404	26	10	10	NUM
admet-1437	404	27	shows	show	VERB
admet-1437	404	28	the	the	DET
admet-1437	404	29	in	in	ADP
admet-1437	404	30	silico	silico	NOUN
admet-1437	404	31	dissolution	dissolution	NOUN
admet-1437	404	32	results	result	NOUN
admet-1437	404	33	obtained	obtain	VERB
admet-1437	404	34	for	for	ADP
admet-1437	404	35	the	the	DET
admet-1437	404	36	selected	select	VERB
admet-1437	404	37	fasted	fast	VERB
admet-1437	404	38	-	-	PUNCT
admet-1437	404	39	state	state	NOUN
admet-1437	404	40	parameter	parameter	NOUN
admet-1437	404	41	combinations	combination	NOUN
admet-1437	404	42	.	.	PUNCT
admet-1437	405	1	figure	figure	NOUN
admet-1437	405	2	10(a	10(a	NUM
admet-1437	405	3	)	)	PUNCT
admet-1437	405	4	shows	show	VERB
admet-1437	405	5	the	the	DET
admet-1437	405	6	dissolved	dissolve	VERB
admet-1437	405	7	mass	mass	NOUN
admet-1437	405	8	fraction	fraction	NOUN
admet-1437	405	9	and	and	CCONJ
admet-1437	405	10	figure	figure	NOUN
admet-1437	405	11	10(b	10(b	NUM
admet-1437	405	12	)	)	PUNCT
admet-1437	405	13	the	the	DET
admet-1437	405	14	related	relate	VERB
admet-1437	405	15	concentration	concentration	NOUN
admet-1437	405	16	at	at	ADP
admet-1437	405	17	equilibrium	equilibrium	NOUN
admet-1437	405	18	.	.	PUNCT
admet-1437	406	1	the	the	PRON
admet-1437	406	2	obtained	obtain	VERB
admet-1437	406	3	in	in	ADP
admet-1437	406	4	silico	silico	NOUN
admet-1437	406	5	results	result	NOUN
admet-1437	406	6	for	for	ADP
admet-1437	406	7	the	the	DET
admet-1437	406	8	selected	select	VERB
admet-1437	406	9	fed	fed	PROPN
admet-1437	406	10	-	-	PUNCT
admet-1437	406	11	state	state	NOUN
admet-1437	406	12	parameter	parameter	NOUN
admet-1437	406	13	combinations	combination	NOUN
admet-1437	406	14	are	be	AUX
admet-1437	406	15	shown	show	VERB
admet-1437	406	16	in	in	ADP
admet-1437	406	17	figure	figure	NOUN
admet-1437	406	18	11(a	11(a	NUM
admet-1437	406	19	)	)	PUNCT
admet-1437	406	20	for	for	ADP
admet-1437	406	21	dissolved	dissolve	VERB
admet-1437	406	22	mass	mass	NOUN
admet-1437	406	23	fraction	fraction	NOUN
admet-1437	406	24	and	and	CCONJ
admet-1437	406	25	in	in	ADP
admet-1437	406	26	figure	figure	NOUN
admet-1437	406	27	11(b	11(b	NUM
admet-1437	406	28	)	)	PUNCT
admet-1437	406	29	for	for	ADP
admet-1437	406	30	the	the	DET
admet-1437	406	31	related	relate	VERB
admet-1437	406	32	concentration	concentration	NOUN
admet-1437	406	33	at	at	ADP
admet-1437	406	34	equilibrium	equilibrium	NOUN
admet-1437	406	35	.	.	PUNCT
admet-1437	407	1	the	the	DET
admet-1437	407	2	drug	drug	NOUN
admet-1437	407	3	nanocrystal	nanocrystal	ADJ
admet-1437	407	4	particle	particle	NOUN
admet-1437	407	5	size	size	NOUN
admet-1437	407	6	distributions	distribution	NOUN
admet-1437	407	7	are	be	AUX
admet-1437	407	8	reported	report	VERB
admet-1437	407	9	by	by	ADP
admet-1437	407	10	median	median	ADJ
admet-1437	407	11	particle	particle	NOUN
admet-1437	407	12	size	size	NOUN
admet-1437	407	13	x50,3	x50,3	PROPN
admet-1437	407	14	.	.	PUNCT
admet-1437	408	1	the	the	DET
admet-1437	408	2	dissolved	dissolve	VERB
admet-1437	408	3	mass	mass	NOUN
admet-1437	408	4	fraction	fraction	NOUN
admet-1437	408	5	increases	increase	NOUN
admet-1437	408	6	with	with	ADP
admet-1437	408	7	decreasing	decrease	VERB
admet-1437	408	8	do	do	NOUN
admet-1437	408	9	(	(	PUNCT
admet-1437	408	10	increasing	increase	VERB
admet-1437	408	11	fluid	fluid	ADJ
admet-1437	408	12	volume	volume	NOUN
admet-1437	408	13	and	and	CCONJ
admet-1437	408	14	decreasing	decrease	VERB
admet-1437	408	15	dose	dose	NOUN
admet-1437	408	16	strength	strength	NOUN
admet-1437	408	17	)	)	PUNCT
admet-1437	408	18	and	and	CCONJ
admet-1437	408	19	with	with	ADP
admet-1437	408	20	decreasing	decrease	VERB
admet-1437	408	21	ph	ph	VERB
admet-1437	408	22	,	,	PUNCT
admet-1437	408	23	due	due	ADP
admet-1437	408	24	to	to	ADP
admet-1437	408	25	the	the	DET
admet-1437	408	26	ph	ph	ADJ
admet-1437	408	27	-	-	ADJ
admet-1437	408	28	dependent	dependent	ADJ
admet-1437	408	29	solubility	solubility	NOUN
admet-1437	408	30	(	(	PUNCT
admet-1437	408	31	compare	compare	NOUN
admet-1437	408	32	also	also	ADV
admet-1437	408	33	figure	figure	VERB
admet-1437	408	34	8)	8)	NUM
admet-1437	408	35	of	of	ADP
admet-1437	408	36	the	the	DET
admet-1437	408	37	investigated	investigate	VERB
admet-1437	408	38	compound	compound	NOUN
admet-1437	408	39	,	,	PUNCT
admet-1437	408	40	see	see	VERB
admet-1437	408	41	figures	figure	NOUN
admet-1437	408	42	10(a	10(a	NUM
admet-1437	408	43	)	)	PUNCT
admet-1437	408	44	and	and	CCONJ
admet-1437	408	45	11(a	11(a	NUM
admet-1437	408	46	)	)	PUNCT
admet-1437	408	47	.	.	PUNCT
admet-1437	409	1	in	in	ADP
admet-1437	409	2	addition	addition	NOUN
admet-1437	409	3	,	,	PUNCT
admet-1437	409	4	different	different	ADJ
admet-1437	409	5	nanocrystal	nanocrystal	ADJ
admet-1437	409	6	particle	particle	NOUN
admet-1437	409	7	size	size	NOUN
admet-1437	409	8	distributions	distribution	NOUN
admet-1437	409	9	show	show	VERB
admet-1437	409	10	a	a	DET
admet-1437	409	11	notable	notable	ADJ
admet-1437	409	12	impact	impact	NOUN
admet-1437	409	13	on	on	ADP
admet-1437	409	14	the	the	DET
admet-1437	409	15	dissolved	dissolve	VERB
admet-1437	409	16	mass	mass	NOUN
admet-1437	409	17	fraction	fraction	NOUN
admet-1437	409	18	,	,	PUNCT
admet-1437	409	19	yielding	yield	VERB
admet-1437	409	20	higher	high	ADJ
admet-1437	409	21	dissolved	dissolve	VERB
admet-1437	409	22	mass	mass	NOUN
admet-1437	409	23	fractions	fraction	NOUN
admet-1437	409	24	with	with	ADP
admet-1437	409	25	decreasing	decrease	VERB
admet-1437	409	26	particle	particle	NOUN
admet-1437	409	27	size	size	NOUN
admet-1437	409	28	.	.	PUNCT
admet-1437	410	1	the	the	DET
admet-1437	410	2	values	value	NOUN
admet-1437	410	3	increase	increase	VERB
admet-1437	410	4	up	up	ADP
admet-1437	410	5	to	to	ADP
admet-1437	410	6	a	a	DET
admet-1437	410	7	factor	factor	NOUN
admet-1437	410	8	of	of	ADP
admet-1437	410	9	about	about	ADV
admet-1437	410	10	2	2	NUM
admet-1437	410	11	in	in	ADP
admet-1437	410	12	accordance	accordance	NOUN
admet-1437	410	13	with	with	ADP
admet-1437	410	14	the	the	DET
admet-1437	410	15	results	result	NOUN
admet-1437	410	16	reported	report	VERB
admet-1437	410	17	above	above	ADV
admet-1437	410	18	.	.	PUNCT
admet-1437	411	1	obviously	obviously	ADV
admet-1437	411	2	,	,	PUNCT
admet-1437	411	3	no	no	DET
admet-1437	411	4	impact	impact	NOUN
admet-1437	411	5	from	from	ADP
admet-1437	411	6	different	different	ADJ
admet-1437	411	7	nanocrystal	nanocrystal	ADJ
admet-1437	411	8	particle	particle	NOUN
admet-1437	411	9	size	size	NOUN
admet-1437	411	10	distributions	distribution	NOUN
admet-1437	411	11	is	be	AUX
admet-1437	411	12	observed	observe	VERB
admet-1437	411	13	for	for	ADP
admet-1437	411	14	scenarios	scenario	NOUN
admet-1437	411	15	with	with	ADP
admet-1437	411	16	do	do	AUX
admet-1437	411	17	≤	≤	NOUN
admet-1437	411	18	1	1	NUM
admet-1437	411	19	,	,	PUNCT
admet-1437	411	20	where	where	SCONJ
admet-1437	411	21	the	the	DET
admet-1437	411	22	thermodynamically	thermodynamically	ADV
admet-1437	411	23	soluble	soluble	ADJ
admet-1437	411	24	amount	amount	NOUN
admet-1437	411	25	is	be	AUX
admet-1437	411	26	equal	equal	ADJ
admet-1437	411	27	or	or	CCONJ
admet-1437	411	28	higher	high	ADJ
admet-1437	411	29	compared	compare	VERB
admet-1437	411	30	to	to	ADP
admet-1437	411	31	the	the	DET
admet-1437	411	32	dose	dose	NOUN
admet-1437	411	33	strength	strength	NOUN
admet-1437	411	34	,	,	PUNCT
admet-1437	411	35	see	see	VERB
admet-1437	411	36	25	25	NUM
admet-1437	411	37	mg	mg	NOUN
admet-1437	411	38	dose	dose	NOUN
admet-1437	411	39	strength	strength	NOUN
admet-1437	411	40	in	in	ADP
admet-1437	411	41	250	250	NUM
admet-1437	411	42	ml	ml	NOUN
admet-1437	411	43	fluid	fluid	NOUN
admet-1437	411	44	of	of	ADP
admet-1437	411	45	ph	ph	ADJ
admet-1437	411	46	2	2	NUM
admet-1437	411	47	,	,	PUNCT
admet-1437	411	48	figure	figure	NOUN
admet-1437	411	49	10(a	10(a	NUM
admet-1437	411	50	)	)	PUNCT
admet-1437	411	51	and	and	CCONJ
admet-1437	411	52	25	25	NUM
admet-1437	411	53	mg	mg	NOUN
admet-1437	411	54	dose	dose	NOUN
admet-1437	411	55	strength	strength	NOUN
admet-1437	411	56	in	in	ADP
admet-1437	411	57	900	900	NUM
admet-1437	411	58	ml	ml	NOUN
admet-1437	411	59	fluid	fluid	ADJ
admet-1437	411	60	volume	volume	NOUN
admet-1437	411	61	of	of	ADP
admet-1437	411	62	ph	ph	ADJ
admet-1437	411	63	3	3	NUM
admet-1437	411	64	,	,	PUNCT
admet-1437	411	65	see	see	VERB
admet-1437	411	66	figure	figure	NOUN
admet-1437	411	67	10(a	10(a	NUM
admet-1437	411	68	)	)	PUNCT
admet-1437	411	69	.	.	PUNCT
admet-1437	412	1	when	when	SCONJ
admet-1437	412	2	looking	look	VERB
admet-1437	412	3	at	at	ADP
admet-1437	412	4	the	the	DET
admet-1437	412	5	concentration	concentration	NOUN
admet-1437	412	6	at	at	ADP
admet-1437	412	7	equilibrium	equilibrium	NOUN
admet-1437	412	8	,	,	PUNCT
admet-1437	412	9	see	see	VERB
admet-1437	412	10	figures	figure	NOUN
admet-1437	412	11	10(b	10(b	NUM
admet-1437	412	12	)	)	PUNCT
admet-1437	412	13	and	and	CCONJ
admet-1437	412	14	11(b	11(b	NUM
admet-1437	412	15	)	)	PUNCT
admet-1437	412	16	,	,	PUNCT
admet-1437	412	17	the	the	DET
admet-1437	412	18	effect	effect	NOUN
admet-1437	412	19	of	of	ADP
admet-1437	412	20	do	do	AUX
admet-1437	412	21	becomes	become	VERB
admet-1437	412	22	visible	visible	ADJ
admet-1437	412	23	(	(	PUNCT
admet-1437	412	24	compare	compare	NOUN
admet-1437	412	25	figure	figure	NOUN
admet-1437	412	26	9	9	NUM
admet-1437	412	27	)	)	PUNCT
admet-1437	412	28	.	.	PUNCT
admet-1437	413	1	although	although	SCONJ
admet-1437	413	2	the	the	DET
admet-1437	413	3	dissolved	dissolve	VERB
admet-1437	413	4	mass	mass	NOUN
admet-1437	413	5	fraction	fraction	NOUN
admet-1437	413	6	is	be	AUX
admet-1437	413	7	lower	low	ADJ
admet-1437	413	8	for	for	ADP
admet-1437	413	9	higher	high	ADJ
admet-1437	413	10	do	do	NOUN
admet-1437	413	11	,	,	PUNCT
admet-1437	413	12	the	the	DET
admet-1437	413	13	resulting	result	VERB
admet-1437	413	14	concentration	concentration	NOUN
admet-1437	413	15	at	at	ADP
admet-1437	413	16	equilibrium	equilibrium	NOUN
admet-1437	413	17	is	be	AUX
admet-1437	413	18	generally	generally	ADV
admet-1437	413	19	increasing	increase	VERB
admet-1437	413	20	with	with	ADP
admet-1437	413	21	do	do	NOUN
admet-1437	413	22	.	.	PUNCT
admet-1437	414	1	these	these	PRON
admet-1437	414	2	in	in	ADP
admet-1437	414	3	silico	silico	NOUN
admet-1437	414	4	dissolution	dissolution	NOUN
admet-1437	414	5	results	result	NOUN
admet-1437	414	6	are	be	AUX
admet-1437	414	7	relevant	relevant	ADJ
admet-1437	414	8	for	for	ADP
admet-1437	414	9	the	the	DET
admet-1437	414	10	in	in	ADP
admet-1437	414	11	vivo	vivo	ADJ
admet-1437	414	12	performance	performance	NOUN
admet-1437	414	13	since	since	SCONJ
admet-1437	414	14	the	the	DET
admet-1437	414	15	concentration	concentration	NOUN
admet-1437	414	16	acts	act	VERB
admet-1437	414	17	as	as	ADP
admet-1437	414	18	a	a	DET
admet-1437	414	19	driving	drive	VERB
admet-1437	414	20	force	force	NOUN
admet-1437	414	21	for	for	ADP
admet-1437	414	22	drug	drug	NOUN
admet-1437	414	23	permeation	permeation	NOUN
admet-1437	414	24	.	.	PUNCT
admet-1437	415	1	consequently	consequently	ADV
admet-1437	415	2	,	,	PUNCT
admet-1437	415	3	the	the	DET
admet-1437	415	4	relative	relative	ADJ
admet-1437	415	5	increase	increase	NOUN
admet-1437	415	6	of	of	ADP
admet-1437	415	7	solubility	solubility	NOUN
admet-1437	415	8	due	due	ADP
admet-1437	415	9	to	to	ADP
admet-1437	415	10	decreasing	decrease	VERB
admet-1437	415	11	particle	particle	NOUN
admet-1437	415	12	size	size	NOUN
admet-1437	415	13	and	and	CCONJ
admet-1437	415	14	increasing	increase	VERB
admet-1437	415	15	do	do	AUX
admet-1437	415	16	may	may	AUX
admet-1437	415	17	help	help	VERB
admet-1437	415	18	elevate	elevate	VERB
admet-1437	415	19	drug	drug	NOUN
admet-1437	415	20	permeation	permeation	NOUN
admet-1437	415	21	and	and	CCONJ
admet-1437	415	22	associated	associated	ADJ
admet-1437	415	23	bioavailability	bioavailability	NOUN
admet-1437	415	24	.	.	PUNCT
admet-1437	416	1	admet	admet	PROPN
admet-1437	416	2	&	&	CCONJ
admet-1437	416	3	dmpk	dmpk	PROPN
admet-1437	416	4	10(4	10(4	NUM
admet-1437	416	5	)	)	PUNCT
admet-1437	416	6	(	(	PUNCT
admet-1437	416	7	2022	2022	NUM
admet-1437	416	8	)	)	PUNCT
admet-1437	416	9	253	253	NUM
admet-1437	416	10	-	-	SYM
admet-1437	416	11	287	287	NUM
admet-1437	416	12	modeling	modeling	NOUN
admet-1437	416	13	of	of	ADP
admet-1437	416	14	drug	drug	NOUN
admet-1437	416	15	nanocrystals	nanocrystal	NOUN
admet-1437	416	16	dissolution	dissolution	NOUN
admet-1437	416	17	doi	doi	PROPN
admet-1437	416	18	:	:	PUNCT
admet-1437	416	19	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	416	20	275	275	NUM
admet-1437	416	21	figure	figure	NOUN
admet-1437	416	22	10	10	NUM
admet-1437	416	23	.	.	PUNCT
admet-1437	416	24	calculated	calculate	VERB
admet-1437	416	25	results	result	NOUN
admet-1437	416	26	for	for	ADP
admet-1437	416	27	in	in	ADP
admet-1437	416	28	vivo	vivo	NOUN
admet-1437	416	29	fasted	fast	VERB
admet-1437	416	30	-	-	PUNCT
admet-1437	416	31	state	state	NOUN
admet-1437	416	32	scenarios	scenario	NOUN
admet-1437	416	33	of	of	ADP
admet-1437	416	34	drug	drug	NOUN
admet-1437	416	35	nanocrystal	nanocrystal	ADJ
admet-1437	416	36	particle	particle	NOUN
admet-1437	416	37	size	size	NOUN
admet-1437	416	38	distributions	distribution	NOUN
admet-1437	416	39	with	with	ADP
admet-1437	416	40	x50,3	x50,3	PROPN
admet-1437	416	41	of	of	ADP
admet-1437	416	42	2443	2443	NUM
admet-1437	416	43	nm	nm	NOUN
admet-1437	416	44	,	,	PUNCT
admet-1437	416	45	261	261	NUM
admet-1437	416	46	nm	nm	NOUN
admet-1437	416	47	,	,	PUNCT
admet-1437	416	48	111	111	NUM
admet-1437	416	49	nm	nm	NOUN
admet-1437	416	50	and	and	CCONJ
admet-1437	416	51	79	79	NUM
admet-1437	416	52	nm	nm	NOUN
admet-1437	416	53	according	accord	VERB
admet-1437	416	54	to	to	ADP
admet-1437	416	55	table	table	NOUN
admet-1437	416	56	2	2	NUM
admet-1437	416	57	,	,	PUNCT
admet-1437	416	58	dose	dose	NOUN
admet-1437	416	59	strengths	strength	NOUN
admet-1437	416	60	of	of	ADP
admet-1437	416	61	25	25	NUM
admet-1437	416	62	mg	mg	NOUN
admet-1437	416	63	and	and	CCONJ
admet-1437	416	64	100	100	NUM
admet-1437	416	65	mg	mg	NOUN
admet-1437	416	66	in	in	ADP
admet-1437	416	67	20	20	NUM
admet-1437	416	68	ml	ml	NOUN
admet-1437	416	69	and	and	CCONJ
admet-1437	416	70	250	250	NUM
admet-1437	416	71	ml	ml	NOUN
admet-1437	416	72	fluid	fluid	NOUN
admet-1437	416	73	of	of	ADP
admet-1437	416	74	ph	ph	ADJ
admet-1437	416	75	2	2	NUM
admet-1437	416	76	.	.	PUNCT
admet-1437	417	1	(	(	PUNCT
admet-1437	417	2	a	a	X
admet-1437	417	3	)	)	PUNCT
admet-1437	417	4	calculated	calculate	VERB
admet-1437	417	5	results	result	NOUN
admet-1437	417	6	for	for	ADP
admet-1437	417	7	dissolved	dissolve	VERB
admet-1437	417	8	mass	mass	NOUN
admet-1437	417	9	fraction	fraction	NOUN
admet-1437	417	10	.	.	PUNCT
admet-1437	418	1	(	(	PUNCT
admet-1437	418	2	b	b	X
admet-1437	418	3	)	)	PUNCT
admet-1437	418	4	calculated	calculate	VERB
admet-1437	418	5	results	result	NOUN
admet-1437	418	6	for	for	ADP
admet-1437	418	7	concentration	concentration	NOUN
admet-1437	418	8	at	at	ADP
admet-1437	418	9	equilibrium	equilibrium	NOUN
admet-1437	418	10	.	.	PUNCT
admet-1437	419	1	figure	figure	NOUN
admet-1437	419	2	11	11	NUM
admet-1437	419	3	.	.	PUNCT
admet-1437	420	1	calculated	calculate	VERB
admet-1437	420	2	results	result	NOUN
admet-1437	420	3	for	for	ADP
admet-1437	420	4	in	in	ADP
admet-1437	420	5	vivo	vivo	ADJ
admet-1437	420	6	fed	feed	VERB
admet-1437	420	7	-	-	PUNCT
admet-1437	420	8	state	state	NOUN
admet-1437	420	9	scenarios	scenario	NOUN
admet-1437	420	10	of	of	ADP
admet-1437	420	11	drug	drug	NOUN
admet-1437	420	12	nanocrystal	nanocrystal	ADJ
admet-1437	420	13	particle	particle	NOUN
admet-1437	420	14	size	size	NOUN
admet-1437	420	15	distributions	distribution	NOUN
admet-1437	420	16	with	with	ADP
admet-1437	420	17	x50,3	x50,3	PROPN
admet-1437	420	18	of	of	ADP
admet-1437	420	19	2443	2443	NUM
admet-1437	420	20	nm	nm	NOUN
admet-1437	420	21	,	,	PUNCT
admet-1437	420	22	261	261	NUM
admet-1437	420	23	nm	nm	NOUN
admet-1437	420	24	,	,	PUNCT
admet-1437	420	25	111	111	NUM
admet-1437	420	26	nm	nm	NOUN
admet-1437	420	27	and	and	CCONJ
admet-1437	420	28	79	79	NUM
admet-1437	420	29	nm	nm	NOUN
admet-1437	420	30	according	accord	VERB
admet-1437	420	31	to	to	ADP
admet-1437	420	32	table	table	NOUN
admet-1437	420	33	2	2	NUM
admet-1437	420	34	,	,	PUNCT
admet-1437	420	35	dose	dose	NOUN
admet-1437	420	36	strengths	strength	NOUN
admet-1437	420	37	of	of	ADP
admet-1437	420	38	25	25	NUM
admet-1437	420	39	mg	mg	NOUN
admet-1437	420	40	and	and	CCONJ
admet-1437	420	41	100	100	NUM
admet-1437	420	42	mg	mg	NOUN
admet-1437	420	43	in	in	ADP
admet-1437	420	44	250	250	NUM
admet-1437	420	45	ml	ml	NOUN
admet-1437	420	46	and	and	CCONJ
admet-1437	420	47	900	900	NUM
admet-1437	420	48	ml	ml	NOUN
admet-1437	420	49	fluid	fluid	NOUN
admet-1437	420	50	of	of	ADP
admet-1437	420	51	ph	ph	ADJ
admet-1437	420	52	3	3	NUM
admet-1437	420	53	and	and	CCONJ
admet-1437	420	54	ph	ph	ADJ
admet-1437	420	55	4.5	4.5	NUM
admet-1437	420	56	.	.	PUNCT
admet-1437	421	1	(	(	PUNCT
admet-1437	421	2	a	a	X
admet-1437	421	3	)	)	PUNCT
admet-1437	421	4	calculated	calculate	VERB
admet-1437	421	5	results	result	NOUN
admet-1437	421	6	for	for	ADP
admet-1437	421	7	dissolved	dissolve	VERB
admet-1437	421	8	mass	mass	NOUN
admet-1437	421	9	fraction	fraction	NOUN
admet-1437	421	10	.	.	PUNCT
admet-1437	422	1	(	(	PUNCT
admet-1437	422	2	b	b	X
admet-1437	422	3	)	)	PUNCT
admet-1437	422	4	calculated	calculate	VERB
admet-1437	422	5	results	result	NOUN
admet-1437	422	6	for	for	ADP
admet-1437	422	7	concentration	concentration	NOUN
admet-1437	422	8	at	at	ADP
admet-1437	422	9	equilibrium	equilibrium	NOUN
admet-1437	422	10	.	.	PUNCT
admet-1437	423	1	the	the	DET
admet-1437	423	2	true	true	ADJ
admet-1437	423	3	supersaturation	supersaturation	NOUN
admet-1437	423	4	identified	identify	VERB
admet-1437	423	5	for	for	ADP
admet-1437	423	6	this	this	DET
admet-1437	423	7	drug	drug	NOUN
admet-1437	423	8	-	-	PUNCT
admet-1437	423	9	stabilizer	stabilizer	NOUN
admet-1437	423	10	system	system	NOUN
admet-1437	423	11	at	at	ADP
admet-1437	423	12	realistic	realistic	ADJ
admet-1437	423	13	in	in	ADP
admet-1437	423	14	vivo	vivo	ADJ
admet-1437	423	15	conditions	condition	NOUN
admet-1437	423	16	for	for	ADP
admet-1437	423	17	ultrafine	ultrafine	NOUN
admet-1437	423	18	drug	drug	NOUN
admet-1437	423	19	nanocrystal	nanocrystal	ADJ
admet-1437	423	20	particle	particle	NOUN
admet-1437	423	21	size	size	NOUN
admet-1437	423	22	distributions	distribution	NOUN
admet-1437	423	23	administered	administer	VERB
admet-1437	423	24	under	under	ADP
admet-1437	423	25	conditions	condition	NOUN
admet-1437	423	26	with	with	ADP
admet-1437	423	27	do	do	AUX
admet-1437	423	28	>	>	X
admet-1437	423	29	>	>	X
admet-1437	423	30	1	1	NUM
admet-1437	423	31	emphasizes	emphasize	VERB
admet-1437	423	32	the	the	DET
admet-1437	423	33	relevance	relevance	NOUN
admet-1437	423	34	for	for	ADP
admet-1437	423	35	potential	potential	ADJ
admet-1437	423	36	bioavailability	bioavailability	NOUN
admet-1437	423	37	improvement	improvement	NOUN
admet-1437	423	38	.	.	PUNCT
admet-1437	424	1	the	the	DET
admet-1437	424	2	importance	importance	NOUN
admet-1437	424	3	of	of	ADP
admet-1437	424	4	supersaturation	supersaturation	NOUN
admet-1437	424	5	to	to	PART
admet-1437	424	6	promote	promote	VERB
admet-1437	424	7	drug	drug	NOUN
admet-1437	424	8	permeation	permeation	NOUN
admet-1437	424	9	and	and	CCONJ
admet-1437	424	10	in	in	ADP
admet-1437	424	11	vivo	vivo	ADJ
admet-1437	424	12	absorption	absorption	NOUN
admet-1437	424	13	is	be	AUX
admet-1437	424	14	extensively	extensively	ADV
admet-1437	424	15	outlined	outline	VERB
admet-1437	424	16	in	in	ADP
admet-1437	424	17	the	the	DET
admet-1437	424	18	context	context	NOUN
admet-1437	424	19	of	of	ADP
admet-1437	424	20	amorphous	amorphous	ADJ
admet-1437	424	21	solid	solid	ADJ
admet-1437	424	22	dispersions	dispersion	NOUN
admet-1437	424	23	as	as	ADP
admet-1437	424	24	an	an	DET
admet-1437	424	25	alternative	alternative	NOUN
admet-1437	424	26	enabling	enable	VERB
admet-1437	424	27	formulation	formulation	NOUN
admet-1437	424	28	to	to	PART
admet-1437	424	29	improve	improve	VERB
admet-1437	424	30	the	the	DET
admet-1437	424	31	bioavailability	bioavailability	NOUN
admet-1437	424	32	of	of	ADP
admet-1437	424	33	poorly	poorly	ADV
admet-1437	424	34	-	-	PUNCT
admet-1437	424	35	soluble	soluble	ADJ
admet-1437	424	36	drugs	drug	NOUN
admet-1437	424	37	for	for	ADP
admet-1437	424	38	oral	oral	ADJ
admet-1437	424	39	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	NOUN
admet-1437	424	40	bonhoeffer	bonhoeffer	PROPN
admet-1437	424	41	et	et	PROPN
admet-1437	424	42	al	al	PROPN
admet-1437	424	43	.	.	PROPN
admet-1437	424	44	admet	admet	PROPN
admet-1437	424	45	&	&	CCONJ
admet-1437	424	46	dmpk	dmpk	PROPN
admet-1437	424	47	10(4	10(4	NUM
admet-1437	424	48	)	)	PUNCT
admet-1437	424	49	(	(	PUNCT
admet-1437	424	50	2022	2022	NUM
admet-1437	424	51	)	)	PUNCT
admet-1437	424	52	253	253	NUM
admet-1437	424	53	-	-	SYM
admet-1437	424	54	287	287	NUM
admet-1437	424	55	276	276	NUM
admet-1437	424	56	administration	administration	NOUN
admet-1437	424	57	[	[	X
admet-1437	424	58	87	87	NUM
admet-1437	424	59	-	-	SYM
admet-1437	424	60	89	89	NUM
admet-1437	424	61	]	]	PUNCT
admet-1437	424	62	.	.	PUNCT
admet-1437	425	1	therefore	therefore	ADV
admet-1437	425	2	,	,	PUNCT
admet-1437	425	3	supersaturation	supersaturation	NOUN
admet-1437	425	4	by	by	ADP
admet-1437	425	5	drug	drug	NOUN
admet-1437	425	6	nanocrystals	nanocrystal	NOUN
admet-1437	425	7	may	may	AUX
admet-1437	425	8	contribute	contribute	VERB
admet-1437	425	9	to	to	ADP
admet-1437	425	10	bioavailability	bioavailability	NOUN
admet-1437	425	11	improvement	improvement	NOUN
admet-1437	425	12	in	in	ADP
admet-1437	425	13	addition	addition	NOUN
admet-1437	425	14	to	to	ADP
admet-1437	425	15	the	the	DET
admet-1437	425	16	generally	generally	ADV
admet-1437	425	17	accepted	accept	VERB
admet-1437	425	18	factor	factor	NOUN
admet-1437	425	19	of	of	ADP
admet-1437	425	20	dissolution	dissolution	NOUN
admet-1437	425	21	rate	rate	NOUN
admet-1437	425	22	improvement	improvement	NOUN
admet-1437	425	23	by	by	ADP
admet-1437	425	24	the	the	DET
admet-1437	425	25	increase	increase	NOUN
admet-1437	425	26	of	of	ADP
admet-1437	425	27	drug	drug	NOUN
admet-1437	425	28	nanocrystal	nanocrystal	ADJ
admet-1437	425	29	-	-	PUNCT
admet-1437	425	30	specific	specific	ADJ
admet-1437	425	31	surface	surface	NOUN
admet-1437	425	32	area	area	NOUN
admet-1437	425	33	.	.	PUNCT
admet-1437	426	1	further	further	ADJ
admet-1437	426	2	mechanisms	mechanism	NOUN
admet-1437	426	3	to	to	PART
admet-1437	426	4	promote	promote	VERB
admet-1437	426	5	potential	potential	ADJ
admet-1437	426	6	bioavailability	bioavailability	NOUN
admet-1437	426	7	gains	gain	NOUN
admet-1437	426	8	from	from	ADP
admet-1437	426	9	ultrafine	ultrafine	NOUN
admet-1437	426	10	drug	drug	NOUN
admet-1437	426	11	nanocrystals	nanocrystal	NOUN
admet-1437	426	12	are	be	AUX
admet-1437	426	13	adhesion	adhesion	NOUN
admet-1437	426	14	to	to	ADP
admet-1437	426	15	the	the	DET
admet-1437	426	16	gut	gut	NOUN
admet-1437	426	17	wall	wall	NOUN
admet-1437	426	18	and	and	CCONJ
admet-1437	426	19	the	the	DET
admet-1437	426	20	penetration	penetration	NOUN
admet-1437	426	21	of	of	ADP
admet-1437	426	22	drug	drug	NOUN
admet-1437	426	23	particles	particle	NOUN
admet-1437	426	24	of	of	ADP
admet-1437	426	25	20	20	NUM
admet-1437	426	26	to	to	PART
admet-1437	426	27	100	100	NUM
admet-1437	426	28	nm	nm	NOUN
admet-1437	427	1	[	[	X
admet-1437	427	2	90	90	NUM
admet-1437	427	3	]	]	PUNCT
admet-1437	427	4	.	.	PUNCT
admet-1437	428	1	however	however	ADV
admet-1437	428	2	,	,	PUNCT
admet-1437	428	3	the	the	DET
admet-1437	428	4	understanding	understanding	NOUN
admet-1437	428	5	of	of	ADP
admet-1437	428	6	these	these	DET
admet-1437	428	7	further	further	ADJ
admet-1437	428	8	mechanisms	mechanism	NOUN
admet-1437	428	9	is	be	AUX
admet-1437	428	10	limited	limit	VERB
admet-1437	428	11	[	[	X
admet-1437	428	12	90	90	NUM
admet-1437	428	13	]	]	PUNCT
admet-1437	428	14	and	and	CCONJ
admet-1437	428	15	they	they	PRON
admet-1437	428	16	are	be	AUX
admet-1437	428	17	not	not	PART
admet-1437	428	18	subject	subject	ADJ
admet-1437	428	19	to	to	ADP
admet-1437	428	20	the	the	DET
admet-1437	428	21	present	present	ADJ
admet-1437	428	22	investigation	investigation	NOUN
admet-1437	428	23	.	.	PUNCT
admet-1437	429	1	modelling	model	VERB
admet-1437	429	2	results	result	NOUN
admet-1437	429	3	for	for	ADP
admet-1437	429	4	in	in	ADP
admet-1437	429	5	vitro	vitro	X
admet-1437	429	6	dissolution	dissolution	NOUN
admet-1437	429	7	further	far	ADV
admet-1437	429	8	in	in	ADP
admet-1437	429	9	silico	silico	NOUN
admet-1437	429	10	studies	study	NOUN
admet-1437	429	11	were	be	AUX
admet-1437	429	12	conducted	conduct	VERB
admet-1437	429	13	to	to	PART
admet-1437	429	14	investigate	investigate	VERB
admet-1437	429	15	the	the	DET
admet-1437	429	16	dissolution	dissolution	ADJ
admet-1437	429	17	behavior	behavior	NOUN
admet-1437	429	18	of	of	ADP
admet-1437	429	19	drug	drug	NOUN
admet-1437	429	20	nanocrystals	nanocrystal	NOUN
admet-1437	429	21	during	during	ADP
admet-1437	429	22	in	in	ADP
admet-1437	429	23	vitro	vitro	X
admet-1437	429	24	dissolution	dissolution	NOUN
admet-1437	429	25	testing	testing	NOUN
admet-1437	429	26	.	.	PUNCT
admet-1437	430	1	a	a	DET
admet-1437	430	2	standard	standard	ADJ
admet-1437	430	3	dissolution	dissolution	NOUN
admet-1437	430	4	test	test	NOUN
admet-1437	430	5	set	set	NOUN
admet-1437	430	6	-	-	PUNCT
admet-1437	430	7	up	up	NOUN
admet-1437	430	8	of	of	ADP
admet-1437	430	9	900	900	NUM
admet-1437	430	10	ml	ml	NOUN
admet-1437	430	11	dissolution	dissolution	ADJ
admet-1437	430	12	media	medium	NOUN
admet-1437	430	13	with	with	ADP
admet-1437	430	14	ph	ph	PROPN
admet-1437	430	15	2	2	NUM
admet-1437	430	16	,	,	PUNCT
admet-1437	430	17	3	3	NUM
admet-1437	430	18	and	and	CCONJ
admet-1437	430	19	4.5	4.5	NUM
admet-1437	430	20	was	be	AUX
admet-1437	430	21	considered	consider	VERB
admet-1437	430	22	.	.	PUNCT
admet-1437	431	1	the	the	DET
admet-1437	431	2	formulation	formulation	NOUN
admet-1437	431	3	parameters	parameter	NOUN
admet-1437	431	4	solid	solid	ADJ
admet-1437	431	5	drug	drug	NOUN
admet-1437	431	6	amount	amount	NOUN
admet-1437	431	7	,	,	PUNCT
admet-1437	431	8	dose	dose	NOUN
admet-1437	431	9	strength	strength	NOUN
admet-1437	431	10	of	of	ADP
admet-1437	431	11	25	25	NUM
admet-1437	431	12	and	and	CCONJ
admet-1437	431	13	100	100	NUM
admet-1437	431	14	mg	mg	NOUN
admet-1437	431	15	and	and	CCONJ
admet-1437	431	16	various	various	ADJ
admet-1437	431	17	nanocrystal	nanocrystal	ADJ
admet-1437	431	18	particle	particle	NOUN
admet-1437	431	19	size	size	NOUN
admet-1437	431	20	distribution	distribution	NOUN
admet-1437	431	21	were	be	AUX
admet-1437	431	22	selected	select	VERB
admet-1437	431	23	according	accord	VERB
admet-1437	431	24	to	to	ADP
admet-1437	431	25	experiments	experiment	NOUN
admet-1437	431	26	no	no	INTJ
admet-1437	431	27	.	.	NOUN
admet-1437	431	28	1	1	NUM
admet-1437	431	29	,	,	PUNCT
admet-1437	431	30	2	2	NUM
admet-1437	431	31	,	,	PUNCT
admet-1437	431	32	5	5	NUM
admet-1437	431	33	and	and	CCONJ
admet-1437	431	34	8	8	NUM
admet-1437	431	35	in	in	ADP
admet-1437	431	36	table	table	NOUN
admet-1437	431	37	2	2	NUM
admet-1437	431	38	.	.	PUNCT
admet-1437	432	1	the	the	DET
admet-1437	432	2	calculated	calculate	VERB
admet-1437	432	3	results	result	NOUN
admet-1437	432	4	are	be	AUX
admet-1437	432	5	shown	show	VERB
admet-1437	432	6	in	in	ADP
admet-1437	432	7	figure	figure	NOUN
admet-1437	432	8	12	12	NUM
admet-1437	432	9	for	for	ADP
admet-1437	432	10	the	the	DET
admet-1437	432	11	resulting	result	VERB
admet-1437	432	12	concentration	concentration	NOUN
admet-1437	432	13	at	at	ADP
admet-1437	432	14	equilibrium	equilibrium	NOUN
admet-1437	432	15	.	.	PUNCT
admet-1437	433	1	for	for	ADP
admet-1437	433	2	scenarios	scenario	NOUN
admet-1437	433	3	with	with	ADP
admet-1437	433	4	do	do	AUX
admet-1437	433	5	<	<	X
admet-1437	433	6	1	1	NUM
admet-1437	433	7	,	,	PUNCT
admet-1437	433	8	all	all	DET
admet-1437	433	9	drug	drug	NOUN
admet-1437	433	10	particles	particle	NOUN
admet-1437	433	11	dissolve	dissolve	VERB
admet-1437	433	12	,	,	PUNCT
admet-1437	433	13	i.e.	i.e.	X
admet-1437	433	14	,	,	PUNCT
admet-1437	433	15	ph	ph	NOUN
admet-1437	433	16	2	2	NUM
admet-1437	433	17	for	for	ADP
admet-1437	433	18	25	25	NUM
admet-1437	433	19	and	and	CCONJ
admet-1437	433	20	100	100	NUM
admet-1437	433	21	mg	mg	NOUN
admet-1437	433	22	and	and	CCONJ
admet-1437	433	23	ph	ph	VERB
admet-1437	433	24	3	3	NUM
admet-1437	433	25	for	for	ADP
admet-1437	433	26	25	25	NUM
admet-1437	433	27	mg	mg	PROPN
admet-1437	433	28	,	,	PUNCT
admet-1437	433	29	reaching	reach	VERB
admet-1437	433	30	100	100	NUM
admet-1437	433	31	%	%	NOUN
admet-1437	433	32	drug	drug	NOUN
admet-1437	433	33	dissolution	dissolution	NOUN
admet-1437	433	34	.	.	PUNCT
admet-1437	434	1	for	for	ADP
admet-1437	434	2	scenarios	scenario	NOUN
admet-1437	434	3	where	where	SCONJ
admet-1437	434	4	do	do	VERB
admet-1437	434	5	>	>	X
admet-1437	434	6	>	>	X
admet-1437	434	7	1	1	NUM
admet-1437	434	8	,	,	PUNCT
admet-1437	434	9	only	only	ADV
admet-1437	434	10	partial	partial	ADJ
admet-1437	434	11	drug	drug	NOUN
admet-1437	434	12	dissolution	dissolution	NOUN
admet-1437	434	13	can	can	AUX
admet-1437	434	14	be	be	AUX
admet-1437	434	15	achieved	achieve	VERB
admet-1437	434	16	,	,	PUNCT
admet-1437	434	17	which	which	PRON
admet-1437	434	18	depends	depend	VERB
admet-1437	434	19	on	on	ADP
admet-1437	434	20	the	the	DET
admet-1437	434	21	drug	drug	NOUN
admet-1437	434	22	nanocrystal	nanocrystal	ADJ
admet-1437	434	23	particle	particle	NOUN
admet-1437	434	24	size	size	NOUN
admet-1437	434	25	distribution	distribution	NOUN
admet-1437	434	26	,	,	PUNCT
admet-1437	434	27	as	as	SCONJ
admet-1437	434	28	seen	see	VERB
admet-1437	434	29	in	in	ADP
admet-1437	434	30	the	the	DET
admet-1437	434	31	in	in	ADP
admet-1437	434	32	vivo	vivo	NOUN
admet-1437	434	33	investigations	investigation	NOUN
admet-1437	434	34	.	.	PUNCT
admet-1437	435	1	thus	thus	ADV
admet-1437	435	2	,	,	PUNCT
admet-1437	435	3	dissolution	dissolution	ADJ
admet-1437	435	4	testing	testing	NOUN
admet-1437	435	5	under	under	ADP
admet-1437	435	6	conditions	condition	NOUN
admet-1437	435	7	with	with	ADP
admet-1437	435	8	do	do	AUX
admet-1437	435	9	>	>	X
admet-1437	435	10	>	>	X
admet-1437	435	11	1	1	NUM
admet-1437	435	12	enables	enable	VERB
admet-1437	435	13	the	the	DET
admet-1437	435	14	distinction	distinction	NOUN
admet-1437	435	15	between	between	ADP
admet-1437	435	16	formulations	formulation	NOUN
admet-1437	435	17	containing	contain	VERB
admet-1437	435	18	different	different	ADJ
admet-1437	435	19	drug	drug	NOUN
admet-1437	435	20	nanocrystal	nanocrystal	ADJ
admet-1437	435	21	particle	particle	NOUN
admet-1437	435	22	size	size	NOUN
admet-1437	435	23	distributions	distribution	NOUN
admet-1437	435	24	.	.	PUNCT
admet-1437	436	1	figure	figure	NOUN
admet-1437	436	2	12	12	NUM
admet-1437	436	3	.	.	PUNCT
admet-1437	437	1	calculated	calculate	VERB
admet-1437	437	2	results	result	NOUN
admet-1437	437	3	for	for	ADP
admet-1437	437	4	resulting	result	VERB
admet-1437	437	5	concentration	concentration	NOUN
admet-1437	437	6	at	at	ADP
admet-1437	437	7	equilibrium	equilibrium	NOUN
admet-1437	437	8	state	state	NOUN
admet-1437	437	9	for	for	ADP
admet-1437	437	10	in	in	X
admet-1437	437	11	vitro	vitro	X
admet-1437	437	12	dissolution	dissolution	ADJ
admet-1437	437	13	scenarios	scenario	NOUN
admet-1437	437	14	of	of	ADP
admet-1437	437	15	drug	drug	NOUN
admet-1437	437	16	nanocrystal	nanocrystal	ADJ
admet-1437	437	17	particle	particle	NOUN
admet-1437	437	18	size	size	NOUN
admet-1437	437	19	distributions	distribution	NOUN
admet-1437	437	20	with	with	ADP
admet-1437	437	21	x50,3	x50,3	PROPN
admet-1437	437	22	of	of	ADP
admet-1437	437	23	2443	2443	NUM
admet-1437	437	24	nm	nm	NOUN
admet-1437	437	25	,	,	PUNCT
admet-1437	437	26	261	261	NUM
admet-1437	437	27	nm	nm	NOUN
admet-1437	437	28	,	,	PUNCT
admet-1437	437	29	111	111	NUM
admet-1437	437	30	nm	nm	NOUN
admet-1437	437	31	and	and	CCONJ
admet-1437	437	32	79	79	NUM
admet-1437	437	33	nm	nm	NOUN
admet-1437	437	34	according	accord	VERB
admet-1437	437	35	to	to	ADP
admet-1437	437	36	table	table	NOUN
admet-1437	437	37	2	2	NUM
admet-1437	437	38	,	,	PUNCT
admet-1437	437	39	dose	dose	NOUN
admet-1437	437	40	strengths	strength	NOUN
admet-1437	437	41	of	of	ADP
admet-1437	437	42	25	25	NUM
admet-1437	437	43	mg	mg	NOUN
admet-1437	437	44	and	and	CCONJ
admet-1437	437	45	100	100	NUM
admet-1437	437	46	mg	mg	NOUN
admet-1437	437	47	in	in	ADP
admet-1437	437	48	900	900	NUM
admet-1437	437	49	ml	ml	NOUN
admet-1437	437	50	dissolution	dissolution	ADJ
admet-1437	437	51	media	medium	NOUN
admet-1437	437	52	of	of	ADP
admet-1437	437	53	ph	ph	ADJ
admet-1437	437	54	2	2	NUM
admet-1437	437	55	,	,	PUNCT
admet-1437	437	56	ph	ph	NOUN
admet-1437	437	57	3	3	NUM
admet-1437	437	58	and	and	CCONJ
admet-1437	437	59	ph	ph	ADJ
admet-1437	437	60	4.5	4.5	NUM
admet-1437	437	61	.	.	PUNCT
admet-1437	438	1	the	the	DET
admet-1437	438	2	established	establish	VERB
admet-1437	438	3	numerical	numerical	ADJ
admet-1437	438	4	model	model	NOUN
admet-1437	438	5	was	be	AUX
admet-1437	438	6	further	far	ADV
admet-1437	438	7	utilized	utilize	VERB
admet-1437	438	8	to	to	PART
admet-1437	438	9	investigate	investigate	VERB
admet-1437	438	10	the	the	DET
admet-1437	438	11	dissolution	dissolution	ADJ
admet-1437	438	12	kinetics	kinetic	NOUN
admet-1437	438	13	of	of	ADP
admet-1437	438	14	drug	drug	NOUN
admet-1437	438	15	nanocrystals	nanocrystal	NOUN
admet-1437	438	16	.	.	PUNCT
admet-1437	439	1	figure	figure	NOUN
admet-1437	439	2	13(a	13(a	NUM
admet-1437	439	3	)	)	PUNCT
admet-1437	439	4	and	and	CCONJ
admet-1437	439	5	(	(	PUNCT
admet-1437	439	6	b	b	X
admet-1437	439	7	)	)	PUNCT
admet-1437	439	8	show	show	VERB
admet-1437	439	9	the	the	DET
admet-1437	439	10	evolution	evolution	NOUN
admet-1437	439	11	of	of	ADP
admet-1437	439	12	concentration	concentration	NOUN
admet-1437	439	13	over	over	ADP
admet-1437	439	14	time	time	NOUN
admet-1437	439	15	for	for	ADP
admet-1437	439	16	different	different	ADJ
admet-1437	439	17	drug	drug	NOUN
admet-1437	439	18	nanocrystal	nanocrystal	ADJ
admet-1437	439	19	particle	particle	NOUN
admet-1437	439	20	size	size	NOUN
admet-1437	439	21	distributions	distribution	NOUN
admet-1437	439	22	according	accord	VERB
admet-1437	439	23	to	to	ADP
admet-1437	439	24	experiments	experiment	NOUN
admet-1437	439	25	no	no	INTJ
admet-1437	439	26	.	.	NOUN
admet-1437	439	27	1	1	NUM
admet-1437	439	28	to	to	ADP
admet-1437	439	29	5	5	NUM
admet-1437	439	30	and	and	CCONJ
admet-1437	439	31	8	8	NUM
admet-1437	439	32	in	in	ADP
admet-1437	439	33	table	table	NOUN
admet-1437	439	34	2	2	NUM
admet-1437	439	35	for	for	ADP
admet-1437	439	36	constant	constant	ADJ
admet-1437	439	37	dissolution	dissolution	NOUN
admet-1437	439	38	conditions	condition	NOUN
admet-1437	439	39	of	of	ADP
admet-1437	439	40	100	100	NUM
admet-1437	439	41	mg	mg	NOUN
admet-1437	439	42	dose	dose	NOUN
admet-1437	439	43	strength	strength	NOUN
admet-1437	439	44	in	in	ADP
admet-1437	439	45	900	900	NUM
admet-1437	439	46	ml	ml	NOUN
admet-1437	439	47	dissolution	dissolution	ADJ
admet-1437	439	48	media	medium	NOUN
admet-1437	439	49	of	of	ADP
admet-1437	439	50	ph	ph	PROPN
admet-1437	439	51	3	3	NUM
admet-1437	439	52	with	with	ADP
admet-1437	439	53	do	do	AUX
admet-1437	439	54	=	=	SYM
admet-1437	439	55	4	4	X
admet-1437	439	56	.	.	PUNCT
admet-1437	440	1	most	most	ADV
admet-1437	440	2	notably	notably	ADV
admet-1437	440	3	,	,	PUNCT
admet-1437	440	4	there	there	PRON
admet-1437	440	5	is	be	VERB
admet-1437	440	6	a	a	DET
admet-1437	440	7	big	big	ADJ
admet-1437	440	8	difference	difference	NOUN
admet-1437	440	9	between	between	ADP
admet-1437	440	10	the	the	DET
admet-1437	440	11	dissolution	dissolution	NOUN
admet-1437	440	12	kinetics	kinetic	NOUN
admet-1437	440	13	of	of	ADP
admet-1437	440	14	the	the	DET
admet-1437	440	15	coarse	coarse	PROPN
admet-1437	440	16	crystal	crystal	NOUN
admet-1437	440	17	suspension	suspension	NOUN
admet-1437	440	18	with	with	ADP
admet-1437	440	19	a	a	DET
admet-1437	440	20	median	median	ADJ
admet-1437	440	21	particle	particle	NOUN
admet-1437	440	22	size	size	NOUN
admet-1437	440	23	x50,3	x50,3	PROPN
admet-1437	440	24	of	of	ADP
admet-1437	440	25	2443	2443	NUM
admet-1437	440	26	nm	nm	NOUN
admet-1437	440	27	and	and	CCONJ
admet-1437	440	28	all	all	DET
admet-1437	440	29	other	other	ADJ
admet-1437	440	30	drug	drug	NOUN
admet-1437	440	31	nanocrystal	nanocrystal	ADJ
admet-1437	440	32	suspensions	suspension	NOUN
admet-1437	440	33	with	with	ADP
admet-1437	440	34	median	median	ADJ
admet-1437	440	35	particle	particle	NOUN
admet-1437	440	36	sizes	size	NOUN
admet-1437	440	37	x50,3	x50,3	PROPN
admet-1437	441	1	of	of	ADP
admet-1437	441	2	258	258	NUM
admet-1437	441	3	nm	nm	NOUN
admet-1437	441	4	or	or	CCONJ
admet-1437	441	5	lower	low	ADJ
admet-1437	441	6	.	.	PUNCT
admet-1437	442	1	ultrafine	ultrafine	NOUN
admet-1437	442	2	drug	drug	PROPN
admet-1437	442	3	nanocrystal	nanocrystal	ADJ
admet-1437	442	4	particle	particle	NOUN
admet-1437	442	5	sizes	size	NOUN
admet-1437	442	6	result	result	VERB
admet-1437	442	7	in	in	ADP
admet-1437	442	8	rapid	rapid	ADJ
admet-1437	442	9	dissolution	dissolution	NOUN
admet-1437	442	10	kinetics	kinetic	NOUN
admet-1437	442	11	and	and	CCONJ
admet-1437	442	12	reach	reach	VERB
admet-1437	442	13	the	the	DET
admet-1437	442	14	equilibrium	equilibrium	NOUN
admet-1437	442	15	state	state	NOUN
admet-1437	442	16	almost	almost	ADV
admet-1437	442	17	instantaneously	instantaneously	ADV
admet-1437	442	18	after	after	ADP
admet-1437	442	19	only	only	ADV
admet-1437	442	20	a	a	DET
admet-1437	442	21	few	few	ADJ
admet-1437	442	22	seconds	second	NOUN
admet-1437	442	23	.	.	PUNCT
admet-1437	443	1	it	it	PRON
admet-1437	443	2	should	should	AUX
admet-1437	443	3	be	be	AUX
admet-1437	443	4	highlighted	highlight	VERB
admet-1437	443	5	that	that	SCONJ
admet-1437	443	6	the	the	DET
admet-1437	443	7	rapid	rapid	ADJ
admet-1437	443	8	dissolution	dissolution	NOUN
admet-1437	443	9	is	be	AUX
admet-1437	443	10	caused	cause	VERB
admet-1437	443	11	by	by	ADP
admet-1437	443	12	the	the	DET
admet-1437	443	13	combination	combination	NOUN
admet-1437	443	14	of	of	ADP
admet-1437	443	15	increased	increase	VERB
admet-1437	443	16	specific	specific	ADJ
admet-1437	443	17	surface	surface	NOUN
admet-1437	443	18	area	area	NOUN
admet-1437	443	19	and	and	CCONJ
admet-1437	443	20	increased	increase	VERB
admet-1437	443	21	apparent	apparent	ADJ
admet-1437	443	22	solubility	solubility	NOUN
admet-1437	443	23	,	,	PUNCT
admet-1437	443	24	both	both	PRON
admet-1437	443	25	due	due	ADP
admet-1437	443	26	to	to	ADP
admet-1437	443	27	the	the	DET
admet-1437	443	28	very	very	ADV
admet-1437	443	29	fine	fine	ADJ
admet-1437	443	30	particle	particle	NOUN
admet-1437	443	31	sizes	size	NOUN
admet-1437	443	32	.	.	PUNCT
admet-1437	444	1	in	in	ADP
admet-1437	444	2	addition	addition	NOUN
admet-1437	444	3	,	,	PUNCT
admet-1437	444	4	the	the	DET
admet-1437	444	5	concentration	concentration	NOUN
admet-1437	444	6	at	at	ADP
admet-1437	444	7	equilibrium	equilibrium	NOUN
admet-1437	444	8	state	state	NOUN
admet-1437	444	9	scales	scale	NOUN
admet-1437	444	10	with	with	ADP
admet-1437	444	11	decreasing	decrease	VERB
admet-1437	444	12	particle	particle	NOUN
admet-1437	444	13	size	size	NOUN
admet-1437	444	14	distribution	distribution	NOUN
admet-1437	444	15	.	.	PUNCT
admet-1437	445	1	due	due	ADP
admet-1437	445	2	to	to	ADP
admet-1437	445	3	the	the	DET
admet-1437	445	4	rapid	rapid	ADJ
admet-1437	445	5	dissolution	dissolution	NOUN
admet-1437	445	6	kinetics	kinetic	NOUN
admet-1437	445	7	,	,	PUNCT
admet-1437	445	8	it	it	PRON
admet-1437	445	9	is	be	AUX
admet-1437	445	10	challenging	challenge	VERB
admet-1437	445	11	for	for	ADP
admet-1437	445	12	standard	standard	NOUN
admet-1437	445	13	in	in	ADP
admet-1437	445	14	vitro	vitro	X
admet-1437	445	15	dissolution	dissolution	NOUN
admet-1437	445	16	testing	testing	NOUN
admet-1437	445	17	under	under	ADP
admet-1437	445	18	sink	sink	NOUN
admet-1437	445	19	conditions	condition	NOUN
admet-1437	445	20	to	to	PART
admet-1437	445	21	discriminate	discriminate	VERB
admet-1437	445	22	between	between	ADP
admet-1437	445	23	different	different	ADJ
admet-1437	445	24	particle	particle	NOUN
admet-1437	445	25	size	size	NOUN
admet-1437	445	26	distributions	distribution	NOUN
admet-1437	445	27	containing	contain	VERB
admet-1437	445	28	ultrafine	ultrafine	NOUN
admet-1437	445	29	drug	drug	NOUN
admet-1437	445	30	nanocrystals	nanocrystal	NOUN
admet-1437	445	31	.	.	PUNCT
admet-1437	446	1	observed	observe	VERB
admet-1437	446	2	differences	difference	NOUN
admet-1437	446	3	in	in	ADP
admet-1437	446	4	dissolution	dissolution	ADJ
admet-1437	446	5	kinetics	kinetic	NOUN
admet-1437	446	6	of	of	ADP
admet-1437	446	7	drug	drug	NOUN
admet-1437	446	8	products	product	NOUN
admet-1437	446	9	containing	contain	VERB
admet-1437	446	10	drug	drug	NOUN
admet-1437	446	11	nanocrystals	nanocrystal	NOUN
admet-1437	446	12	of	of	ADP
admet-1437	446	13	different	different	ADJ
admet-1437	446	14	admet	admet	NOUN
admet-1437	446	15	&	&	CCONJ
admet-1437	446	16	dmpk	dmpk	PROPN
admet-1437	446	17	10(4	10(4	NUM
admet-1437	446	18	)	)	PUNCT
admet-1437	446	19	(	(	PUNCT
admet-1437	446	20	2022	2022	NUM
admet-1437	446	21	)	)	PUNCT
admet-1437	446	22	253	253	NUM
admet-1437	446	23	-	-	SYM
admet-1437	446	24	287	287	NUM
admet-1437	446	25	modeling	modeling	NOUN
admet-1437	446	26	of	of	ADP
admet-1437	446	27	drug	drug	NOUN
admet-1437	446	28	nanocrystals	nanocrystal	NOUN
admet-1437	446	29	dissolution	dissolution	NOUN
admet-1437	446	30	doi	doi	PROPN
admet-1437	446	31	:	:	PUNCT
admet-1437	446	32	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	446	33	277	277	NUM
admet-1437	446	34	particle	particle	NOUN
admet-1437	446	35	sizes	size	NOUN
admet-1437	446	36	,	,	PUNCT
admet-1437	446	37	must	must	AUX
admet-1437	446	38	therefore	therefore	ADV
admet-1437	446	39	be	be	AUX
admet-1437	446	40	related	relate	VERB
admet-1437	446	41	to	to	ADP
admet-1437	446	42	other	other	ADJ
admet-1437	446	43	functional	functional	ADJ
admet-1437	446	44	properties	property	NOUN
admet-1437	446	45	of	of	ADP
admet-1437	446	46	the	the	DET
admet-1437	446	47	drug	drug	NOUN
admet-1437	446	48	product	product	NOUN
admet-1437	446	49	,	,	PUNCT
admet-1437	446	50	i.e.	i.e.	X
admet-1437	446	51	,	,	PUNCT
admet-1437	446	52	disintegration	disintegration	NOUN
admet-1437	446	53	and	and	CCONJ
admet-1437	446	54	dispersion	dispersion	NOUN
admet-1437	446	55	.	.	PUNCT
admet-1437	447	1	figure	figure	NOUN
admet-1437	447	2	13	13	NUM
admet-1437	447	3	.	.	PUNCT
admet-1437	448	1	calculated	calculate	VERB
admet-1437	448	2	results	result	NOUN
admet-1437	448	3	for	for	ADP
admet-1437	448	4	the	the	DET
admet-1437	448	5	evolution	evolution	NOUN
admet-1437	448	6	of	of	ADP
admet-1437	448	7	concentration	concentration	NOUN
admet-1437	448	8	for	for	ADP
admet-1437	448	9	in	in	ADP
admet-1437	448	10	vitro	vitro	X
admet-1437	448	11	dissolution	dissolution	ADJ
admet-1437	448	12	scenarios	scenario	NOUN
admet-1437	448	13	of	of	ADP
admet-1437	448	14	drug	drug	NOUN
admet-1437	448	15	nanocrystal	nanocrystal	ADJ
admet-1437	448	16	particle	particle	NOUN
admet-1437	448	17	size	size	NOUN
admet-1437	448	18	distributions	distribution	NOUN
admet-1437	448	19	with	with	ADP
admet-1437	448	20	x50,3	x50,3	PROPN
admet-1437	448	21	of	of	ADP
admet-1437	448	22	2443	2443	NUM
admet-1437	448	23	nm	nm	NOUN
admet-1437	448	24	,	,	PUNCT
admet-1437	448	25	261	261	NUM
admet-1437	448	26	nm	nm	NOUN
admet-1437	448	27	,	,	PUNCT
admet-1437	448	28	201	201	NUM
admet-1437	448	29	nm	nm	NOUN
admet-1437	448	30	,	,	PUNCT
admet-1437	448	31	140	140	NUM
admet-1437	448	32	nm	nm	NOUN
admet-1437	448	33	,	,	PUNCT
admet-1437	448	34	111	111	NUM
admet-1437	448	35	nm	nm	NOUN
admet-1437	448	36	and	and	CCONJ
admet-1437	448	37	79	79	NUM
admet-1437	448	38	nm	nm	NOUN
admet-1437	448	39	according	accord	VERB
admet-1437	448	40	to	to	ADP
admet-1437	448	41	table	table	NOUN
admet-1437	448	42	2	2	NUM
admet-1437	448	43	,	,	PUNCT
admet-1437	448	44	100	100	NUM
admet-1437	448	45	mg	mg	NOUN
admet-1437	448	46	dose	dose	NOUN
admet-1437	448	47	strength	strength	NOUN
admet-1437	448	48	in	in	ADP
admet-1437	448	49	900	900	NUM
admet-1437	448	50	ml	ml	NOUN
admet-1437	448	51	dissolution	dissolution	ADJ
admet-1437	448	52	media	medium	NOUN
admet-1437	448	53	of	of	ADP
admet-1437	448	54	ph	ph	PROPN
admet-1437	448	55	3	3	NUM
admet-1437	448	56	and	and	CCONJ
admet-1437	448	57	do	do	VERB
admet-1437	448	58	=	=	SYM
admet-1437	448	59	4	4	X
admet-1437	448	60	.	.	PUNCT
admet-1437	449	1	(	(	PUNCT
admet-1437	449	2	a	a	X
admet-1437	449	3	)	)	PUNCT
admet-1437	449	4	calculated	calculate	VERB
admet-1437	449	5	results	result	NOUN
admet-1437	449	6	for	for	ADP
admet-1437	449	7	full	full	ADJ
admet-1437	449	8	dissolution	dissolution	NOUN
admet-1437	449	9	of	of	ADP
admet-1437	449	10	all	all	DET
admet-1437	449	11	scenarios	scenario	NOUN
admet-1437	449	12	.	.	PUNCT
admet-1437	450	1	(	(	PUNCT
admet-1437	450	2	b	b	X
admet-1437	450	3	)	)	PUNCT
admet-1437	450	4	calculated	calculate	VERB
admet-1437	450	5	results	result	NOUN
admet-1437	450	6	identical	identical	ADJ
admet-1437	450	7	to	to	ADP
admet-1437	450	8	(	(	PUNCT
admet-1437	450	9	a	a	X
admet-1437	450	10	)	)	PUNCT
admet-1437	450	11	but	but	CCONJ
admet-1437	450	12	highlighted	highlight	VERB
admet-1437	450	13	for	for	ADP
admet-1437	450	14	the	the	DET
admet-1437	450	15	initial	initial	ADJ
admet-1437	450	16	time	time	NOUN
admet-1437	450	17	period	period	NOUN
admet-1437	450	18	.	.	PUNCT
admet-1437	451	1	the	the	DET
admet-1437	451	2	initial	initial	ADJ
admet-1437	451	3	particle	particle	NOUN
admet-1437	451	4	size	size	NOUN
admet-1437	451	5	distribution	distribution	NOUN
admet-1437	451	6	at	at	ADP
admet-1437	451	7	t	t	NOUN
admet-1437	451	8	=	=	SYM
admet-1437	451	9	0	0	NUM
admet-1437	451	10	and	and	CCONJ
admet-1437	451	11	the	the	DET
admet-1437	451	12	resulting	result	VERB
admet-1437	451	13	particle	particle	NOUN
admet-1437	451	14	size	size	NOUN
admet-1437	451	15	distribution	distribution	NOUN
admet-1437	451	16	at	at	ADP
admet-1437	451	17	equilibrium	equilibrium	NOUN
admet-1437	451	18	are	be	AUX
admet-1437	451	19	shown	show	VERB
admet-1437	451	20	in	in	ADP
admet-1437	451	21	figures	figure	NOUN
admet-1437	451	22	14(a	14(a	NUM
admet-1437	451	23	)	)	PUNCT
admet-1437	451	24	,	,	PUNCT
admet-1437	451	25	(	(	PUNCT
admet-1437	451	26	b	b	X
admet-1437	451	27	)	)	PUNCT
admet-1437	451	28	and	and	CCONJ
admet-1437	451	29	(	(	PUNCT
admet-1437	451	30	c	c	NOUN
admet-1437	451	31	)	)	PUNCT
admet-1437	451	32	for	for	ADP
admet-1437	451	33	drug	drug	NOUN
admet-1437	451	34	nanocrystals	nanocrystal	NOUN
admet-1437	451	35	with	with	ADP
admet-1437	451	36	median	median	ADJ
admet-1437	451	37	particle	particle	NOUN
admet-1437	451	38	size	size	NOUN
admet-1437	451	39	x50,3	x50,3	PROPN
admet-1437	451	40	of	of	ADP
admet-1437	451	41	2443	2443	NUM
admet-1437	451	42	nm	nm	NOUN
admet-1437	451	43	,	,	PUNCT
admet-1437	451	44	201	201	NUM
admet-1437	451	45	nm	nm	NOUN
admet-1437	451	46	and	and	CCONJ
admet-1437	451	47	79	79	NUM
admet-1437	451	48	nm	nm	NOUN
admet-1437	451	49	,	,	PUNCT
admet-1437	451	50	see	see	VERB
admet-1437	451	51	experiment	experiment	NOUN
admet-1437	451	52	no	no	NOUN
admet-1437	451	53	.	.	NOUN
admet-1437	451	54	1	1	NUM
admet-1437	451	55	,	,	PUNCT
admet-1437	451	56	3	3	NUM
admet-1437	451	57	and	and	CCONJ
admet-1437	451	58	8	8	NUM
admet-1437	451	59	in	in	ADP
admet-1437	451	60	table	table	NOUN
admet-1437	451	61	2	2	NUM
admet-1437	451	62	.	.	PUNCT
admet-1437	452	1	the	the	DET
admet-1437	452	2	biggest	big	ADJ
admet-1437	452	3	change	change	NOUN
admet-1437	452	4	in	in	ADP
admet-1437	452	5	the	the	DET
admet-1437	452	6	shape	shape	NOUN
admet-1437	452	7	of	of	ADP
admet-1437	452	8	the	the	DET
admet-1437	452	9	particle	particle	NOUN
admet-1437	452	10	size	size	NOUN
admet-1437	452	11	distribution	distribution	NOUN
admet-1437	452	12	is	be	AUX
admet-1437	452	13	seen	see	VERB
admet-1437	452	14	for	for	ADP
admet-1437	452	15	the	the	DET
admet-1437	452	16	finest	fine	ADJ
admet-1437	452	17	drug	drug	NOUN
admet-1437	452	18	nanocrystals	nanocrystal	NOUN
admet-1437	452	19	,	,	PUNCT
admet-1437	452	20	where	where	SCONJ
admet-1437	452	21	the	the	DET
admet-1437	452	22	fine	fine	ADJ
admet-1437	452	23	fraction	fraction	NOUN
admet-1437	452	24	is	be	AUX
admet-1437	452	25	notably	notably	ADV
admet-1437	452	26	reduced	reduce	VERB
admet-1437	452	27	,	,	PUNCT
admet-1437	452	28	see	see	VERB
admet-1437	452	29	figure	figure	NOUN
admet-1437	452	30	14(c	14(c	NUM
admet-1437	452	31	)	)	PUNCT
admet-1437	452	32	.	.	PUNCT
admet-1437	453	1	on	on	ADP
admet-1437	453	2	the	the	DET
admet-1437	453	3	other	other	ADJ
admet-1437	453	4	hand	hand	NOUN
admet-1437	453	5	,	,	PUNCT
admet-1437	453	6	the	the	DET
admet-1437	453	7	shape	shape	NOUN
admet-1437	453	8	of	of	ADP
admet-1437	453	9	the	the	DET
admet-1437	453	10	coarsest	coarse	ADJ
admet-1437	453	11	crystal	crystal	NOUN
admet-1437	453	12	suspension	suspension	NOUN
admet-1437	453	13	remains	remain	VERB
admet-1437	453	14	almost	almost	ADV
admet-1437	453	15	unchanged	unchanged	ADJ
admet-1437	453	16	,	,	PUNCT
admet-1437	453	17	see	see	VERB
admet-1437	453	18	figure	figure	NOUN
admet-1437	453	19	14(a	14(a	NUM
admet-1437	453	20	)	)	PUNCT
admet-1437	453	21	.	.	PUNCT
admet-1437	454	1	this	this	PRON
admet-1437	454	2	is	be	AUX
admet-1437	454	3	caused	cause	VERB
admet-1437	454	4	by	by	ADP
admet-1437	454	5	the	the	DET
admet-1437	454	6	relative	relative	ADJ
admet-1437	454	7	difference	difference	NOUN
admet-1437	454	8	in	in	ADP
admet-1437	454	9	apparent	apparent	ADJ
admet-1437	454	10	solubility	solubility	NOUN
admet-1437	454	11	of	of	ADP
admet-1437	454	12	the	the	DET
admet-1437	454	13	particles	particle	NOUN
admet-1437	454	14	at	at	ADP
admet-1437	454	15	the	the	DET
admet-1437	454	16	lower	low	ADJ
admet-1437	454	17	and	and	CCONJ
admet-1437	454	18	upper	upper	ADJ
admet-1437	454	19	end	end	NOUN
admet-1437	454	20	of	of	ADP
admet-1437	454	21	the	the	DET
admet-1437	454	22	particle	particle	NOUN
admet-1437	454	23	size	size	NOUN
admet-1437	454	24	distribution	distribution	NOUN
admet-1437	454	25	,	,	PUNCT
admet-1437	454	26	which	which	PRON
admet-1437	454	27	is	be	AUX
admet-1437	454	28	more	more	ADV
admet-1437	454	29	pronounced	pronounced	ADJ
admet-1437	454	30	for	for	ADP
admet-1437	454	31	smaller	small	ADJ
admet-1437	454	32	particle	particle	NOUN
admet-1437	454	33	sizes	size	NOUN
admet-1437	454	34	.	.	PUNCT
admet-1437	455	1	hence	hence	ADV
admet-1437	455	2	,	,	PUNCT
admet-1437	455	3	the	the	DET
admet-1437	455	4	smallest	small	ADJ
admet-1437	455	5	particles	particle	NOUN
admet-1437	455	6	dissolve	dissolve	VERB
admet-1437	455	7	much	much	ADV
admet-1437	455	8	faster	fast	ADV
admet-1437	455	9	than	than	ADP
admet-1437	455	10	the	the	DET
admet-1437	455	11	coarser	coarse	ADJ
admet-1437	455	12	particles	particle	NOUN
admet-1437	455	13	,	,	PUNCT
admet-1437	455	14	resulting	result	VERB
admet-1437	455	15	in	in	ADP
admet-1437	455	16	a	a	DET
admet-1437	455	17	change	change	NOUN
admet-1437	455	18	in	in	ADP
admet-1437	455	19	the	the	DET
admet-1437	455	20	shape	shape	NOUN
admet-1437	455	21	of	of	ADP
admet-1437	455	22	the	the	DET
admet-1437	455	23	particle	particle	NOUN
admet-1437	455	24	size	size	NOUN
admet-1437	455	25	distribution	distribution	NOUN
admet-1437	455	26	.	.	PUNCT
admet-1437	456	1	this	this	PRON
admet-1437	456	2	emphasizes	emphasize	VERB
admet-1437	456	3	once	once	ADV
admet-1437	456	4	more	more	ADJ
admet-1437	456	5	the	the	DET
admet-1437	456	6	need	need	NOUN
admet-1437	456	7	to	to	PART
admet-1437	456	8	consider	consider	VERB
admet-1437	456	9	the	the	DET
admet-1437	456	10	entire	entire	ADJ
admet-1437	456	11	particle	particle	NOUN
admet-1437	456	12	size	size	NOUN
admet-1437	456	13	distribution	distribution	NOUN
admet-1437	456	14	by	by	ADP
admet-1437	456	15	a	a	DET
admet-1437	456	16	time	time	NOUN
admet-1437	456	17	-	-	PUNCT
admet-1437	456	18	resolved	resolve	VERB
admet-1437	456	19	calculation	calculation	NOUN
admet-1437	456	20	.	.	PUNCT
admet-1437	457	1	it	it	PRON
admet-1437	457	2	should	should	AUX
admet-1437	457	3	be	be	AUX
admet-1437	457	4	noted	note	VERB
admet-1437	457	5	that	that	SCONJ
admet-1437	457	6	the	the	DET
admet-1437	457	7	smallest	small	ADJ
admet-1437	457	8	still	still	ADV
admet-1437	457	9	remaining	remain	VERB
admet-1437	457	10	particle	particle	NOUN
admet-1437	457	11	size	size	NOUN
admet-1437	457	12	at	at	ADP
admet-1437	457	13	the	the	DET
admet-1437	457	14	end	end	NOUN
admet-1437	457	15	of	of	ADP
admet-1437	457	16	the	the	DET
admet-1437	457	17	dissolution	dissolution	NOUN
admet-1437	457	18	correlates	correlate	VERB
admet-1437	457	19	directly	directly	ADV
admet-1437	457	20	to	to	ADP
admet-1437	457	21	the	the	DET
admet-1437	457	22	calculated	calculated	ADJ
admet-1437	457	23	concentration	concentration	NOUN
admet-1437	457	24	at	at	ADP
admet-1437	457	25	equilibrium	equilibrium	NOUN
admet-1437	457	26	.	.	PUNCT
admet-1437	458	1	figure	figure	NOUN
admet-1437	458	2	15	15	NUM
admet-1437	458	3	shows	show	VERB
admet-1437	458	4	the	the	DET
admet-1437	458	5	change	change	NOUN
admet-1437	458	6	in	in	ADP
admet-1437	458	7	concentration	concentration	NOUN
admet-1437	458	8	over	over	ADP
admet-1437	458	9	time	time	NOUN
admet-1437	458	10	for	for	ADP
admet-1437	458	11	the	the	DET
admet-1437	458	12	drug	drug	NOUN
admet-1437	458	13	nanocrystals	nanocrystal	NOUN
admet-1437	458	14	with	with	ADP
admet-1437	458	15	median	median	ADJ
admet-1437	458	16	particle	particle	NOUN
admet-1437	458	17	size	size	NOUN
admet-1437	458	18	x50,3	x50,3	PROPN
admet-1437	459	1	of	of	ADP
admet-1437	459	2	111	111	NUM
admet-1437	459	3	nm	nm	NOUN
admet-1437	459	4	at	at	ADP
admet-1437	459	5	do	do	AUX
admet-1437	459	6	values	value	NOUN
admet-1437	459	7	from	from	ADP
admet-1437	459	8	1	1	NUM
admet-1437	459	9	to	to	PART
admet-1437	459	10	100	100	NUM
admet-1437	459	11	.	.	PUNCT
admet-1437	460	1	naturally	naturally	ADV
admet-1437	460	2	,	,	PUNCT
admet-1437	460	3	the	the	DET
admet-1437	460	4	dissolution	dissolution	NOUN
admet-1437	460	5	kinetics	kinetic	NOUN
admet-1437	460	6	is	be	AUX
admet-1437	460	7	faster	fast	ADJ
admet-1437	460	8	for	for	ADP
admet-1437	460	9	higher	high	ADJ
admet-1437	460	10	do	do	AUX
admet-1437	460	11	values	value	NOUN
admet-1437	460	12	since	since	SCONJ
admet-1437	460	13	the	the	DET
admet-1437	460	14	more	more	ADV
admet-1437	460	15	absolute	absolute	ADJ
admet-1437	460	16	surface	surface	NOUN
admet-1437	460	17	area	area	NOUN
admet-1437	460	18	is	be	AUX
admet-1437	460	19	available	available	ADJ
admet-1437	460	20	for	for	ADP
admet-1437	460	21	dissolution	dissolution	NOUN
admet-1437	460	22	.	.	PUNCT
admet-1437	461	1	in	in	ADP
admet-1437	461	2	addition	addition	NOUN
admet-1437	461	3	,	,	PUNCT
admet-1437	461	4	an	an	DET
admet-1437	461	5	increased	increase	VERB
admet-1437	461	6	amount	amount	NOUN
admet-1437	461	7	of	of	ADP
admet-1437	461	8	fine	fine	ADJ
admet-1437	461	9	fraction	fraction	NOUN
admet-1437	461	10	is	be	AUX
admet-1437	461	11	present	present	ADJ
admet-1437	461	12	,	,	PUNCT
admet-1437	461	13	which	which	PRON
admet-1437	461	14	dissolves	dissolve	VERB
admet-1437	461	15	faster	fast	ADV
admet-1437	461	16	due	due	ADJ
admet-1437	461	17	to	to	ADP
admet-1437	461	18	increased	increase	VERB
admet-1437	461	19	apparent	apparent	ADJ
admet-1437	461	20	solubility	solubility	NOUN
admet-1437	461	21	,	,	PUNCT
admet-1437	461	22	which	which	PRON
admet-1437	461	23	further	far	ADV
admet-1437	461	24	enhances	enhance	VERB
admet-1437	461	25	the	the	DET
admet-1437	461	26	dissolution	dissolution	NOUN
admet-1437	461	27	rate	rate	NOUN
admet-1437	461	28	and	and	CCONJ
admet-1437	461	29	results	result	NOUN
admet-1437	461	30	in	in	ADP
admet-1437	461	31	a	a	DET
admet-1437	461	32	notable	notable	ADJ
admet-1437	461	33	increase	increase	NOUN
admet-1437	461	34	of	of	ADP
admet-1437	461	35	the	the	DET
admet-1437	461	36	resulting	result	VERB
admet-1437	461	37	concentration	concentration	NOUN
admet-1437	461	38	at	at	ADP
admet-1437	461	39	the	the	DET
admet-1437	461	40	equilibrium	equilibrium	NOUN
admet-1437	461	41	state	state	NOUN
admet-1437	461	42	.	.	PUNCT
admet-1437	462	1	the	the	DET
admet-1437	462	2	initial	initial	ADJ
admet-1437	462	3	particle	particle	NOUN
admet-1437	462	4	size	size	NOUN
admet-1437	462	5	distribution	distribution	NOUN
admet-1437	462	6	at	at	ADP
admet-1437	462	7	t	t	NOUN
admet-1437	462	8	=	=	SYM
admet-1437	462	9	0	0	NUM
admet-1437	462	10	and	and	CCONJ
admet-1437	462	11	the	the	DET
admet-1437	462	12	resulting	result	VERB
admet-1437	462	13	particle	particle	NOUN
admet-1437	462	14	size	size	NOUN
admet-1437	462	15	distribution	distribution	NOUN
admet-1437	462	16	at	at	ADP
admet-1437	462	17	equilibrium	equilibrium	NOUN
admet-1437	462	18	are	be	AUX
admet-1437	462	19	shown	show	VERB
admet-1437	462	20	in	in	ADP
admet-1437	462	21	figures	figure	NOUN
admet-1437	462	22	16(a	16(a	NUM
admet-1437	462	23	)	)	PUNCT
admet-1437	462	24	,	,	PUNCT
admet-1437	462	25	(	(	PUNCT
admet-1437	462	26	b	b	X
admet-1437	462	27	)	)	PUNCT
admet-1437	462	28	and	and	CCONJ
admet-1437	462	29	(	(	PUNCT
admet-1437	462	30	c	c	NOUN
admet-1437	462	31	)	)	PUNCT
admet-1437	462	32	for	for	AUX
admet-1437	462	33	do	do	VERB
admet-1437	462	34	numbers	number	NOUN
admet-1437	462	35	of	of	ADP
admet-1437	462	36	1	1	NUM
admet-1437	462	37	,	,	PUNCT
admet-1437	462	38	4	4	NUM
admet-1437	462	39	and	and	CCONJ
admet-1437	462	40	40	40	NUM
admet-1437	462	41	for	for	ADP
admet-1437	462	42	drug	drug	NOUN
admet-1437	462	43	nanocrystals	nanocrystal	NOUN
admet-1437	462	44	with	with	ADP
admet-1437	462	45	median	median	ADJ
admet-1437	462	46	particle	particle	NOUN
admet-1437	462	47	size	size	NOUN
admet-1437	462	48	x50,3	x50,3	PROPN
admet-1437	462	49	of	of	ADP
admet-1437	462	50	111	111	NUM
admet-1437	462	51	nm	nm	NOUN
admet-1437	462	52	.	.	PUNCT
admet-1437	463	1	for	for	SCONJ
admet-1437	463	2	do	do	AUX
admet-1437	463	3	=	=	SYM
admet-1437	463	4	1	1	NUM
admet-1437	463	5	all	all	DET
admet-1437	463	6	material	material	NOUN
admet-1437	463	7	dissolved	dissolve	VERB
admet-1437	463	8	,	,	PUNCT
admet-1437	463	9	hence	hence	ADV
admet-1437	463	10	no	no	DET
admet-1437	463	11	resulting	result	VERB
admet-1437	463	12	particle	particle	NOUN
admet-1437	463	13	size	size	NOUN
admet-1437	463	14	distribution	distribution	NOUN
admet-1437	463	15	is	be	AUX
admet-1437	463	16	shown	show	VERB
admet-1437	463	17	,	,	PUNCT
admet-1437	463	18	see	see	VERB
admet-1437	463	19	figure	figure	NOUN
admet-1437	463	20	16(a	16(a	NUM
admet-1437	463	21	)	)	PUNCT
admet-1437	463	22	.	.	PUNCT
admet-1437	464	1	for	for	ADP
admet-1437	464	2	increasing	increase	VERB
admet-1437	464	3	do	do	AUX
admet-1437	464	4	,	,	PUNCT
admet-1437	464	5	the	the	DET
admet-1437	464	6	change	change	NOUN
admet-1437	464	7	in	in	ADP
admet-1437	464	8	the	the	DET
admet-1437	464	9	shape	shape	NOUN
admet-1437	464	10	of	of	ADP
admet-1437	464	11	the	the	DET
admet-1437	464	12	particle	particle	NOUN
admet-1437	464	13	size	size	NOUN
admet-1437	464	14	distribution	distribution	NOUN
admet-1437	464	15	decreases	decrease	VERB
admet-1437	464	16	.	.	PUNCT
admet-1437	465	1	while	while	SCONJ
admet-1437	465	2	a	a	DET
admet-1437	465	3	notable	notable	ADJ
admet-1437	465	4	change	change	NOUN
admet-1437	465	5	is	be	AUX
admet-1437	465	6	seen	see	VERB
admet-1437	465	7	with	with	ADP
admet-1437	465	8	do	do	AUX
admet-1437	465	9	=	=	SYM
admet-1437	465	10	4	4	NUM
admet-1437	465	11	,	,	PUNCT
admet-1437	465	12	barely	barely	ADV
admet-1437	465	13	any	any	DET
admet-1437	465	14	change	change	NOUN
admet-1437	465	15	is	be	AUX
admet-1437	465	16	observed	observe	VERB
admet-1437	465	17	with	with	ADP
admet-1437	465	18	do	do	NOUN
admet-1437	465	19	=	=	SYM
admet-1437	465	20	40	40	NUM
admet-1437	465	21	.	.	PUNCT
admet-1437	466	1	similarly	similarly	ADV
admet-1437	466	2	,	,	PUNCT
admet-1437	466	3	as	as	SCONJ
admet-1437	466	4	observed	observe	VERB
admet-1437	466	5	before	before	ADV
admet-1437	466	6	,	,	PUNCT
admet-1437	466	7	the	the	DET
admet-1437	466	8	change	change	NOUN
admet-1437	466	9	of	of	ADP
admet-1437	466	10	shape	shape	NOUN
admet-1437	466	11	of	of	ADP
admet-1437	466	12	the	the	DET
admet-1437	466	13	particle	particle	NOUN
admet-1437	466	14	size	size	NOUN
admet-1437	466	15	distribution	distribution	NOUN
admet-1437	466	16	is	be	AUX
admet-1437	466	17	the	the	DET
admet-1437	466	18	biggest	big	ADJ
admet-1437	466	19	for	for	ADP
admet-1437	466	20	the	the	DET
admet-1437	466	21	fine	fine	ADJ
admet-1437	466	22	fraction	fraction	NOUN
admet-1437	466	23	due	due	ADP
admet-1437	466	24	to	to	ADP
admet-1437	466	25	increased	increase	VERB
admet-1437	466	26	apparent	apparent	ADJ
admet-1437	466	27	solubility	solubility	NOUN
admet-1437	466	28	and	and	CCONJ
admet-1437	466	29	the	the	DET
admet-1437	466	30	smallest	small	ADJ
admet-1437	466	31	still	still	ADV
admet-1437	466	32	remaining	remain	VERB
admet-1437	466	33	particle	particle	NOUN
admet-1437	466	34	size	size	NOUN
admet-1437	466	35	at	at	ADP
admet-1437	466	36	the	the	DET
admet-1437	466	37	end	end	NOUN
admet-1437	466	38	of	of	ADP
admet-1437	466	39	the	the	DET
admet-1437	466	40	dissolution	dissolution	NOUN
admet-1437	466	41	correlates	correlate	VERB
admet-1437	466	42	directly	directly	ADV
admet-1437	466	43	to	to	ADP
admet-1437	466	44	the	the	DET
admet-1437	466	45	apparent	apparent	ADJ
admet-1437	466	46	solubility	solubility	NOUN
admet-1437	466	47	at	at	ADP
admet-1437	466	48	the	the	DET
admet-1437	466	49	equilibrium	equilibrium	NOUN
admet-1437	466	50	state	state	NOUN
admet-1437	466	51	.	.	PUNCT
admet-1437	467	1	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	X
admet-1437	467	2	bonhoeffer	bonhoeffer	PROPN
admet-1437	467	3	et	et	PROPN
admet-1437	467	4	al	al	PROPN
admet-1437	467	5	.	.	PROPN
admet-1437	467	6	admet	admet	PROPN
admet-1437	467	7	&	&	CCONJ
admet-1437	467	8	dmpk	dmpk	PROPN
admet-1437	467	9	10(4	10(4	NUM
admet-1437	467	10	)	)	PUNCT
admet-1437	467	11	(	(	PUNCT
admet-1437	467	12	2022	2022	NUM
admet-1437	467	13	)	)	PUNCT
admet-1437	467	14	253	253	NUM
admet-1437	467	15	-	-	SYM
admet-1437	467	16	287	287	NUM
admet-1437	467	17	278	278	NUM
admet-1437	467	18	figure	figure	NOUN
admet-1437	467	19	14	14	NUM
admet-1437	467	20	.	.	PUNCT
admet-1437	468	1	calculated	calculate	VERB
admet-1437	468	2	results	result	NOUN
admet-1437	468	3	for	for	ADP
admet-1437	468	4	the	the	DET
admet-1437	468	5	evolution	evolution	NOUN
admet-1437	468	6	of	of	ADP
admet-1437	468	7	nanocrystal	nanocrystal	ADJ
admet-1437	468	8	particle	particle	NOUN
admet-1437	468	9	size	size	NOUN
admet-1437	468	10	distributions	distribution	NOUN
admet-1437	468	11	for	for	ADP
admet-1437	468	12	in	in	X
admet-1437	468	13	vitro	vitro	X
admet-1437	468	14	dissolution	dissolution	ADJ
admet-1437	468	15	scenarios	scenario	NOUN
admet-1437	468	16	with	with	ADP
admet-1437	468	17	100	100	NUM
admet-1437	468	18	mg	mg	NOUN
admet-1437	468	19	dose	dose	NOUN
admet-1437	468	20	strength	strength	NOUN
admet-1437	468	21	in	in	ADP
admet-1437	468	22	900	900	NUM
admet-1437	468	23	ml	ml	NOUN
admet-1437	468	24	dissolution	dissolution	ADJ
admet-1437	468	25	media	medium	NOUN
admet-1437	468	26	of	of	ADP
admet-1437	468	27	ph	ph	PROPN
admet-1437	468	28	3	3	NUM
admet-1437	468	29	and	and	CCONJ
admet-1437	468	30	do	do	VERB
admet-1437	468	31	=	=	SYM
admet-1437	468	32	4	4	NUM
admet-1437	468	33	,	,	PUNCT
admet-1437	468	34	corresponding	correspond	VERB
admet-1437	468	35	to	to	PART
admet-1437	468	36	figure	figure	VERB
admet-1437	468	37	12	12	NUM
admet-1437	468	38	.	.	PUNCT
admet-1437	469	1	(	(	PUNCT
admet-1437	469	2	a	a	X
admet-1437	469	3	)	)	PUNCT
admet-1437	469	4	x50,3	x50,3	PUNCT
admet-1437	470	1	=	=	PUNCT
admet-1437	470	2	2443	2443	NUM
admet-1437	470	3	nm	nm	NOUN
admet-1437	470	4	.	.	PUNCT
admet-1437	471	1	(	(	PUNCT
admet-1437	471	2	b	b	X
admet-1437	471	3	)	)	PUNCT
admet-1437	471	4	x50,3	x50,3	PUNCT
admet-1437	472	1	=	=	SYM
admet-1437	472	2	201	201	NUM
admet-1437	472	3	nm	nm	NOUN
admet-1437	472	4	.	.	PUNCT
admet-1437	473	1	(	(	PUNCT
admet-1437	473	2	c	c	X
admet-1437	473	3	)	)	PUNCT
admet-1437	473	4	x50,3	x50,3	PUNCT
admet-1437	474	1	=	=	SYM
admet-1437	474	2	79	79	NUM
admet-1437	474	3	nm	nm	NOUN
admet-1437	474	4	.	.	PUNCT
admet-1437	475	1	figure	figure	NOUN
admet-1437	475	2	15	15	NUM
admet-1437	475	3	.	.	PUNCT
admet-1437	476	1	calculated	calculate	VERB
admet-1437	476	2	results	result	NOUN
admet-1437	476	3	for	for	ADP
admet-1437	476	4	the	the	DET
admet-1437	476	5	evolution	evolution	NOUN
admet-1437	476	6	of	of	ADP
admet-1437	476	7	concentration	concentration	NOUN
admet-1437	476	8	for	for	ADP
admet-1437	476	9	in	in	ADP
admet-1437	476	10	vitro	vitro	X
admet-1437	476	11	dissolution	dissolution	ADJ
admet-1437	476	12	scenarios	scenario	NOUN
admet-1437	476	13	for	for	ADP
admet-1437	476	14	drug	drug	NOUN
admet-1437	476	15	nanocrystal	nanocrystal	ADJ
admet-1437	476	16	particle	particle	NOUN
admet-1437	476	17	size	size	NOUN
admet-1437	476	18	distributions	distribution	NOUN
admet-1437	476	19	x50,3	x50,3	PUNCT
admet-1437	477	1	=	=	SYM
admet-1437	477	2	111	111	NUM
admet-1437	477	3	nm	nm	NOUN
admet-1437	477	4	according	accord	VERB
admet-1437	477	5	to	to	ADP
admet-1437	477	6	table	table	NOUN
admet-1437	477	7	2	2	NUM
admet-1437	477	8	in	in	ADP
admet-1437	477	9	900	900	NUM
admet-1437	477	10	ml	ml	NOUN
admet-1437	477	11	dissolution	dissolution	ADJ
admet-1437	477	12	media	medium	NOUN
admet-1437	477	13	of	of	ADP
admet-1437	477	14	ph	ph	PROPN
admet-1437	477	15	3	3	NUM
admet-1437	477	16	with	with	ADP
admet-1437	477	17	different	different	ADJ
admet-1437	477	18	ratios	ratio	NOUN
admet-1437	477	19	of	of	ADP
admet-1437	477	20	the	the	DET
admet-1437	477	21	available	available	ADJ
admet-1437	477	22	solid	solid	ADJ
admet-1437	477	23	drug	drug	NOUN
admet-1437	477	24	to	to	ADP
admet-1437	477	25	the	the	DET
admet-1437	477	26	thermodynamically	thermodynamically	ADV
admet-1437	477	27	soluble	soluble	ADJ
admet-1437	477	28	amount	amount	NOUN
admet-1437	477	29	do	do	NOUN
admet-1437	477	30	of	of	ADP
admet-1437	477	31	1	1	NUM
admet-1437	477	32	,	,	PUNCT
admet-1437	477	33	2	2	NUM
admet-1437	477	34	,	,	PUNCT
admet-1437	477	35	4	4	NUM
admet-1437	477	36	,	,	PUNCT
admet-1437	477	37	10	10	NUM
admet-1437	477	38	,	,	PUNCT
admet-1437	477	39	40	40	NUM
admet-1437	477	40	and	and	CCONJ
admet-1437	477	41	100	100	NUM
admet-1437	477	42	.	.	PUNCT
admet-1437	478	1	admet	admet	PROPN
admet-1437	478	2	&	&	CCONJ
admet-1437	478	3	dmpk	dmpk	PROPN
admet-1437	478	4	10(4	10(4	NUM
admet-1437	478	5	)	)	PUNCT
admet-1437	478	6	(	(	PUNCT
admet-1437	478	7	2022	2022	NUM
admet-1437	478	8	)	)	PUNCT
admet-1437	478	9	253	253	NUM
admet-1437	478	10	-	-	SYM
admet-1437	478	11	287	287	NUM
admet-1437	478	12	modeling	modeling	NOUN
admet-1437	478	13	of	of	ADP
admet-1437	478	14	drug	drug	NOUN
admet-1437	478	15	nanocrystals	nanocrystal	NOUN
admet-1437	478	16	dissolution	dissolution	NOUN
admet-1437	478	17	doi	doi	PROPN
admet-1437	478	18	:	:	PUNCT
admet-1437	478	19	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	478	20	279	279	NUM
admet-1437	478	21	figure	figure	NOUN
admet-1437	478	22	16	16	NUM
admet-1437	478	23	.	.	PUNCT
admet-1437	479	1	calculated	calculate	VERB
admet-1437	479	2	results	result	NOUN
admet-1437	479	3	for	for	ADP
admet-1437	479	4	the	the	DET
admet-1437	479	5	evolution	evolution	NOUN
admet-1437	479	6	of	of	ADP
admet-1437	479	7	nanocrystal	nanocrystal	ADJ
admet-1437	479	8	particle	particle	NOUN
admet-1437	479	9	size	size	NOUN
admet-1437	479	10	distributions	distribution	NOUN
admet-1437	479	11	for	for	ADP
admet-1437	479	12	in	in	X
admet-1437	479	13	vitro	vitro	X
admet-1437	479	14	dissolution	dissolution	ADJ
admet-1437	479	15	scenarios	scenario	NOUN
admet-1437	479	16	with	with	ADP
admet-1437	479	17	initial	initial	ADJ
admet-1437	479	18	particle	particle	NOUN
admet-1437	479	19	size	size	NOUN
admet-1437	479	20	x50,3	x50,3	PUNCT
admet-1437	480	1	=	=	SYM
admet-1437	480	2	111	111	NUM
admet-1437	480	3	nm	nm	NOUN
admet-1437	480	4	in	in	ADP
admet-1437	480	5	900	900	NUM
admet-1437	480	6	ml	ml	NOUN
admet-1437	480	7	dissolution	dissolution	ADJ
admet-1437	480	8	media	medium	NOUN
admet-1437	480	9	of	of	ADP
admet-1437	480	10	ph	ph	PROPN
admet-1437	480	11	3	3	NUM
admet-1437	480	12	corresponding	correspond	VERB
admet-1437	480	13	to	to	PART
admet-1437	480	14	figure	figure	VERB
admet-1437	480	15	12	12	NUM
admet-1437	480	16	.	.	PUNCT
admet-1437	481	1	(	(	PUNCT
admet-1437	481	2	a	a	X
admet-1437	481	3	)	)	PUNCT
admet-1437	481	4	do	do	VERB
admet-1437	481	5	=	=	SYM
admet-1437	481	6	1	1	X
admet-1437	481	7	.	.	PUNCT
admet-1437	482	1	(	(	PUNCT
admet-1437	482	2	b	b	X
admet-1437	482	3	)	)	PUNCT
admet-1437	482	4	do	do	VERB
admet-1437	482	5	=	=	SYM
admet-1437	482	6	4	4	X
admet-1437	482	7	.	.	PUNCT
admet-1437	483	1	(	(	PUNCT
admet-1437	483	2	c	c	X
admet-1437	483	3	)	)	PUNCT
admet-1437	483	4	do	do	VERB
admet-1437	483	5	=	=	SYM
admet-1437	483	6	40	40	NUM
admet-1437	483	7	.	.	PUNCT
admet-1437	484	1	conclusions	conclusion	NOUN
admet-1437	484	2	nanocrystals	nanocrystal	NOUN
admet-1437	484	3	with	with	ADP
admet-1437	484	4	different	different	ADJ
admet-1437	484	5	particle	particle	NOUN
admet-1437	484	6	size	size	NOUN
admet-1437	484	7	distributions	distribution	NOUN
admet-1437	484	8	were	be	AUX
admet-1437	484	9	manufactured	manufacture	VERB
admet-1437	484	10	for	for	ADP
admet-1437	484	11	a	a	DET
admet-1437	484	12	drug	drug	NOUN
admet-1437	484	13	compound	compound	NOUN
admet-1437	484	14	with	with	ADP
admet-1437	484	15	constant	constant	ADJ
admet-1437	484	16	formulation	formulation	NOUN
admet-1437	484	17	composition	composition	NOUN
admet-1437	484	18	utilizing	utilize	VERB
admet-1437	484	19	wet	wet	ADJ
admet-1437	484	20	media	medium	NOUN
admet-1437	484	21	milling	mill	VERB
admet-1437	484	22	technology	technology	NOUN
admet-1437	484	23	with	with	ADP
admet-1437	484	24	an	an	DET
admet-1437	484	25	industrially	industrially	ADV
admet-1437	484	26	applicable	applicable	ADJ
admet-1437	484	27	process	process	NOUN
admet-1437	484	28	design	design	NOUN
admet-1437	484	29	.	.	PUNCT
admet-1437	485	1	the	the	DET
admet-1437	485	2	finest	fine	ADJ
admet-1437	485	3	manufactured	manufacture	VERB
admet-1437	485	4	size	size	NOUN
admet-1437	485	5	distribution	distribution	NOUN
admet-1437	485	6	resulted	result	VERB
admet-1437	485	7	in	in	ADP
admet-1437	485	8	a	a	DET
admet-1437	485	9	particle	particle	NOUN
admet-1437	485	10	size	size	NOUN
admet-1437	485	11	x10	x10	PROPN
admet-1437	485	12	/	/	SYM
admet-1437	485	13	x50	x50	PROPN
admet-1437	485	14	/	/	SYM
admet-1437	485	15	x90	x90	PROPN
admet-1437	485	16	of	of	ADP
admet-1437	485	17	47	47	NUM
admet-1437	485	18	/	/	SYM
admet-1437	485	19	79	79	NUM
admet-1437	485	20	/	/	SYM
admet-1437	485	21	133	133	NUM
admet-1437	485	22	nm	nm	NOUN
admet-1437	485	23	.	.	PUNCT
admet-1437	486	1	high	high	ADJ
admet-1437	486	2	magnification	magnification	NOUN
admet-1437	486	3	microscopy	microscopy	NOUN
admet-1437	486	4	even	even	ADV
admet-1437	486	5	showed	show	VERB
admet-1437	486	6	ultrafine	ultrafine	NOUN
admet-1437	486	7	nanocrystals	nanocrystal	NOUN
admet-1437	486	8	with	with	ADP
admet-1437	486	9	an	an	DET
admet-1437	486	10	almost	almost	ADV
admet-1437	486	11	sphere	sphere	NOUN
admet-1437	486	12	-	-	PUNCT
admet-1437	486	13	like	like	ADJ
admet-1437	486	14	shape	shape	NOUN
admet-1437	486	15	of	of	ADP
admet-1437	486	16	about	about	ADV
admet-1437	486	17	20	20	NUM
admet-1437	486	18	nm	nm	NOUN
admet-1437	486	19	.	.	PUNCT
admet-1437	487	1	the	the	DET
admet-1437	487	2	manufactured	manufacture	VERB
admet-1437	487	3	nanocrystals	nanocrystal	NOUN
admet-1437	487	4	are	be	AUX
admet-1437	487	5	considered	consider	VERB
admet-1437	487	6	crystalline	crystalline	ADJ
admet-1437	487	7	,	,	PUNCT
admet-1437	487	8	however	however	ADV
admet-1437	487	9	,	,	PUNCT
admet-1437	487	10	for	for	ADP
admet-1437	487	11	particles	particle	NOUN
admet-1437	487	12	below	below	ADP
admet-1437	487	13	200	200	NUM
admet-1437	487	14	nm	nm	NOUN
admet-1437	487	15	an	an	DET
admet-1437	487	16	increasing	increase	VERB
admet-1437	487	17	amount	amount	NOUN
admet-1437	487	18	of	of	ADP
admet-1437	487	19	amorphous	amorphous	ADJ
admet-1437	487	20	content	content	NOUN
admet-1437	487	21	with	with	ADP
admet-1437	487	22	decreasing	decrease	VERB
admet-1437	487	23	particle	particle	NOUN
admet-1437	487	24	size	size	NOUN
admet-1437	487	25	becomes	become	VERB
admet-1437	487	26	detectable	detectable	ADJ
admet-1437	487	27	and	and	CCONJ
admet-1437	487	28	quantifiable	quantifiable	ADJ
admet-1437	487	29	with	with	ADP
admet-1437	487	30	reflection	reflection	NOUN
admet-1437	487	31	x	x	NOUN
admet-1437	487	32	-	-	NOUN
admet-1437	487	33	ray	ray	NOUN
admet-1437	487	34	powder	powder	NOUN
admet-1437	487	35	diffraction	diffraction	NOUN
admet-1437	487	36	up	up	ADP
admet-1437	487	37	to	to	ADP
admet-1437	487	38	a	a	DET
admet-1437	487	39	maximum	maximum	NOUN
admet-1437	487	40	of	of	ADP
admet-1437	487	41	about	about	ADV
admet-1437	487	42	20	20	NUM
admet-1437	487	43	%	%	NOUN
admet-1437	487	44	amorphous	amorphous	ADJ
admet-1437	487	45	content	content	NOUN
admet-1437	487	46	for	for	ADP
admet-1437	487	47	the	the	DET
admet-1437	487	48	finest	fine	ADJ
admet-1437	487	49	drug	drug	NOUN
admet-1437	487	50	nanocrystal	nanocrystal	ADJ
admet-1437	487	51	particle	particle	NOUN
admet-1437	487	52	size	size	NOUN
admet-1437	487	53	distribution	distribution	NOUN
admet-1437	487	54	.	.	PUNCT
admet-1437	488	1	this	this	DET
admet-1437	488	2	amorphous	amorphous	ADJ
admet-1437	488	3	content	content	NOUN
admet-1437	488	4	is	be	AUX
admet-1437	488	5	considered	consider	VERB
admet-1437	488	6	an	an	DET
admet-1437	488	7	intrinsic	intrinsic	ADJ
admet-1437	488	8	property	property	NOUN
admet-1437	488	9	and	and	CCONJ
admet-1437	488	10	was	be	AUX
admet-1437	488	11	explained	explain	VERB
admet-1437	488	12	by	by	ADP
admet-1437	488	13	a	a	DET
admet-1437	488	14	simple	simple	ADJ
admet-1437	488	15	model	model	NOUN
admet-1437	488	16	estimating	estimate	VERB
admet-1437	488	17	the	the	DET
admet-1437	488	18	intrinsic	intrinsic	ADJ
admet-1437	488	19	surface	surface	NOUN
admet-1437	488	20	amorphicity	amorphicity	NOUN
admet-1437	488	21	of	of	ADP
admet-1437	488	22	the	the	DET
admet-1437	488	23	nanocrystals	nanocrystal	NOUN
admet-1437	488	24	due	due	ADP
admet-1437	488	25	to	to	ADP
admet-1437	488	26	the	the	DET
admet-1437	488	27	high	high	ADJ
admet-1437	488	28	specific	specific	ADJ
admet-1437	488	29	surface	surface	NOUN
admet-1437	488	30	area	area	NOUN
admet-1437	488	31	and	and	CCONJ
admet-1437	488	32	related	relate	VERB
admet-1437	488	33	small	small	ADJ
admet-1437	488	34	particle	particle	NOUN
admet-1437	488	35	size	size	NOUN
admet-1437	488	36	/	/	SYM
admet-1437	488	37	high	high	ADJ
admet-1437	488	38	curvature	curvature	NOUN
admet-1437	488	39	.	.	PUNCT
admet-1437	489	1	the	the	DET
admet-1437	489	2	experimentally	experimentally	ADV
admet-1437	489	3	determined	determine	VERB
admet-1437	489	4	apparent	apparent	ADJ
admet-1437	489	5	solubility	solubility	NOUN
admet-1437	489	6	of	of	ADP
admet-1437	489	7	the	the	DET
admet-1437	489	8	different	different	ADJ
admet-1437	489	9	nanocrystal	nanocrystal	ADJ
admet-1437	489	10	particle	particle	NOUN
admet-1437	489	11	size	size	NOUN
admet-1437	489	12	distributions	distribution	NOUN
admet-1437	489	13	showed	show	VERB
admet-1437	489	14	consistent	consistent	ADJ
admet-1437	489	15	results	result	NOUN
admet-1437	489	16	at	at	ADP
admet-1437	489	17	ph	ph	PROPN
admet-1437	489	18	2	2	NUM
admet-1437	489	19	,	,	PUNCT
admet-1437	489	20	ph	ph	NOUN
admet-1437	489	21	3	3	NUM
admet-1437	489	22	and	and	CCONJ
admet-1437	489	23	ph	ph	ADJ
admet-1437	489	24	4.5	4.5	NUM
admet-1437	489	25	,	,	PUNCT
admet-1437	489	26	with	with	ADP
admet-1437	489	27	a	a	DET
admet-1437	489	28	notable	notable	ADJ
admet-1437	489	29	increase	increase	NOUN
admet-1437	489	30	of	of	ADP
admet-1437	489	31	the	the	DET
admet-1437	489	32	apparent	apparent	ADJ
admet-1437	489	33	solubility	solubility	NOUN
admet-1437	489	34	from	from	ADP
admet-1437	489	35	coarse	coarse	ADJ
admet-1437	489	36	micron	micron	NOUN
admet-1437	489	37	-	-	PUNCT
admet-1437	489	38	sized	sized	ADJ
admet-1437	489	39	crystal	crystal	NOUN
admet-1437	489	40	to	to	PART
admet-1437	489	41	ultrafine	ultrafine	VERB
admet-1437	489	42	nanocrystals	nanocrystal	NOUN
admet-1437	489	43	particle	particle	NOUN
admet-1437	489	44	size	size	NOUN
admet-1437	489	45	distribution	distribution	NOUN
admet-1437	489	46	.	.	PUNCT
admet-1437	490	1	the	the	DET
admet-1437	490	2	highest	high	ADJ
admet-1437	490	3	supersaturation	supersaturation	NOUN
admet-1437	490	4	was	be	AUX
admet-1437	490	5	identified	identify	VERB
admet-1437	490	6	for	for	ADP
admet-1437	490	7	the	the	DET
admet-1437	490	8	finest	fine	ADJ
admet-1437	490	9	nanocrystal	nanocrystal	ADJ
admet-1437	490	10	size	size	NOUN
admet-1437	490	11	distribution	distribution	NOUN
admet-1437	490	12	with	with	ADP
admet-1437	490	13	almost	almost	ADV
admet-1437	490	14	a	a	PRON
admet-1437	490	15	factor	factor	NOUN
admet-1437	490	16	of	of	ADP
admet-1437	490	17	2	2	NUM
admet-1437	490	18	compared	compare	VERB
admet-1437	490	19	to	to	ADP
admet-1437	490	20	the	the	DET
admet-1437	490	21	thermodynamic	thermodynamic	ADJ
admet-1437	490	22	solubility	solubility	NOUN
admet-1437	490	23	of	of	ADP
admet-1437	490	24	the	the	DET
admet-1437	490	25	coarse	coarse	ADJ
admet-1437	490	26	drug	drug	NOUN
admet-1437	490	27	compound	compound	NOUN
admet-1437	490	28	.	.	PUNCT
admet-1437	491	1	an	an	DET
admet-1437	491	2	increasing	increase	VERB
admet-1437	491	3	dose	dose	NOUN
admet-1437	491	4	number	number	NOUN
admet-1437	491	5	(	(	PUNCT
admet-1437	491	6	do	do	AUX
admet-1437	491	7	)	)	PUNCT
admet-1437	491	8	notably	notably	ADV
admet-1437	491	9	influences	influence	VERB
admet-1437	491	10	the	the	DET
admet-1437	491	11	measured	measure	VERB
admet-1437	491	12	apparent	apparent	ADJ
admet-1437	491	13	solubility	solubility	NOUN
admet-1437	491	14	due	due	ADP
admet-1437	491	15	to	to	ADP
admet-1437	491	16	the	the	DET
admet-1437	491	17	increasing	increase	VERB
admet-1437	491	18	amount	amount	NOUN
admet-1437	491	19	of	of	ADP
admet-1437	491	20	fine	fine	ADJ
admet-1437	491	21	fraction	fraction	NOUN
admet-1437	491	22	available	available	ADJ
admet-1437	491	23	for	for	ADP
admet-1437	491	24	dissolution	dissolution	NOUN
admet-1437	491	25	.	.	PUNCT
admet-1437	492	1	interestingly	interestingly	ADV
admet-1437	492	2	,	,	PUNCT
admet-1437	492	3	the	the	DET
admet-1437	492	4	results	result	NOUN
admet-1437	492	5	obtained	obtain	VERB
admet-1437	492	6	for	for	ADP
admet-1437	492	7	apparent	apparent	ADJ
admet-1437	492	8	solubility	solubility	NOUN
admet-1437	492	9	against	against	ADP
admet-1437	492	10	drug	drug	NOUN
admet-1437	492	11	particle	particle	NOUN
admet-1437	492	12	size	size	NOUN
admet-1437	492	13	coincide	coincide	NOUN
admet-1437	492	14	in	in	ADP
admet-1437	492	15	trend	trend	NOUN
admet-1437	492	16	with	with	ADP
admet-1437	492	17	the	the	DET
admet-1437	492	18	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	NOUN
admet-1437	492	19	bonhoeffer	bonhoeffer	PROPN
admet-1437	492	20	et	et	PROPN
admet-1437	492	21	al	al	PROPN
admet-1437	492	22	.	.	PROPN
admet-1437	492	23	admet	admet	PROPN
admet-1437	492	24	&	&	CCONJ
admet-1437	492	25	dmpk	dmpk	PROPN
admet-1437	492	26	10(4	10(4	NUM
admet-1437	492	27	)	)	PUNCT
admet-1437	492	28	(	(	PUNCT
admet-1437	492	29	2022	2022	NUM
admet-1437	492	30	)	)	PUNCT
admet-1437	492	31	253	253	NUM
admet-1437	492	32	-	-	SYM
admet-1437	492	33	287	287	NUM
admet-1437	492	34	280	280	NUM
admet-1437	492	35	results	result	NOUN
admet-1437	492	36	obtained	obtain	VERB
admet-1437	492	37	on	on	ADP
admet-1437	492	38	the	the	DET
admet-1437	492	39	amorphous	amorphous	ADJ
admet-1437	492	40	content	content	NOUN
admet-1437	492	41	associated	associate	VERB
admet-1437	492	42	with	with	ADP
admet-1437	492	43	the	the	DET
admet-1437	492	44	intrinsic	intrinsic	ADJ
admet-1437	492	45	amorphous	amorphous	ADJ
admet-1437	492	46	surface	surface	NOUN
admet-1437	492	47	layer	layer	NOUN
admet-1437	492	48	.	.	PUNCT
admet-1437	493	1	the	the	DET
admet-1437	493	2	theoretical	theoretical	ADJ
admet-1437	493	3	apparent	apparent	ADJ
admet-1437	493	4	solubility	solubility	NOUN
admet-1437	493	5	calculated	calculate	VERB
admet-1437	493	6	by	by	ADP
admet-1437	493	7	the	the	DET
admet-1437	493	8	established	establish	VERB
admet-1437	493	9	numerical	numerical	ADJ
admet-1437	493	10	model	model	NOUN
admet-1437	493	11	for	for	ADP
admet-1437	493	12	drug	drug	NOUN
admet-1437	493	13	nanocrystal	nanocrystal	PROPN
admet-1437	493	14	dissolution	dissolution	NOUN
admet-1437	493	15	in	in	ADP
admet-1437	493	16	comparison	comparison	NOUN
admet-1437	493	17	to	to	ADP
admet-1437	493	18	the	the	DET
admet-1437	493	19	experimentally	experimentally	ADV
admet-1437	493	20	determined	determine	VERB
admet-1437	493	21	apparent	apparent	ADJ
admet-1437	493	22	solubility	solubility	NOUN
admet-1437	493	23	showed	show	VERB
admet-1437	493	24	conclusive	conclusive	ADJ
admet-1437	493	25	results	result	NOUN
admet-1437	493	26	.	.	PUNCT
admet-1437	494	1	the	the	DET
admet-1437	494	2	assumption	assumption	NOUN
admet-1437	494	3	of	of	ADP
admet-1437	494	4	monodisperse	monodisperse	NOUN
admet-1437	494	5	particle	particle	NOUN
admet-1437	494	6	sizes	size	NOUN
admet-1437	494	7	for	for	ADP
admet-1437	494	8	calculation	calculation	NOUN
admet-1437	494	9	failed	fail	VERB
admet-1437	494	10	to	to	PART
admet-1437	494	11	describe	describe	VERB
admet-1437	494	12	the	the	DET
admet-1437	494	13	experimentally	experimentally	ADV
admet-1437	494	14	determined	determine	VERB
admet-1437	494	15	apparent	apparent	ADJ
admet-1437	494	16	solubility	solubility	NOUN
admet-1437	494	17	for	for	ADP
admet-1437	494	18	the	the	DET
admet-1437	494	19	polydisperse	polydisperse	NOUN
admet-1437	494	20	nanocrystal	nanocrystal	ADJ
admet-1437	494	21	particle	particle	NOUN
admet-1437	494	22	size	size	NOUN
admet-1437	494	23	distributions	distribution	NOUN
admet-1437	494	24	by	by	ADP
admet-1437	494	25	notably	notably	ADV
admet-1437	494	26	underpredicting	underpredicte	VERB
admet-1437	494	27	the	the	DET
admet-1437	494	28	experimental	experimental	ADJ
admet-1437	494	29	values	value	NOUN
admet-1437	494	30	,	,	PUNCT
admet-1437	494	31	as	as	ADV
admet-1437	494	32	well	well	ADV
admet-1437	494	33	as	as	ADP
admet-1437	494	34	the	the	DET
admet-1437	494	35	inability	inability	NOUN
admet-1437	494	36	to	to	PART
admet-1437	494	37	describe	describe	VERB
admet-1437	494	38	the	the	DET
admet-1437	494	39	influence	influence	NOUN
admet-1437	494	40	of	of	ADP
admet-1437	494	41	the	the	DET
admet-1437	494	42	dose	dose	NOUN
admet-1437	494	43	number	number	NOUN
admet-1437	494	44	.	.	PUNCT
admet-1437	495	1	the	the	DET
admet-1437	495	2	consideration	consideration	NOUN
admet-1437	495	3	of	of	ADP
admet-1437	495	4	the	the	DET
admet-1437	495	5	entire	entire	ADJ
admet-1437	495	6	particle	particle	NOUN
admet-1437	495	7	size	size	NOUN
admet-1437	495	8	distribution	distribution	NOUN
admet-1437	495	9	and	and	CCONJ
admet-1437	495	10	its	its	PRON
admet-1437	495	11	evolution	evolution	NOUN
admet-1437	495	12	over	over	ADP
admet-1437	495	13	time	time	NOUN
admet-1437	495	14	is	be	AUX
admet-1437	495	15	essential	essential	ADJ
admet-1437	495	16	to	to	PART
admet-1437	495	17	reliably	reliably	VERB
admet-1437	495	18	and	and	CCONJ
admet-1437	495	19	accurately	accurately	ADV
admet-1437	495	20	describe	describe	VERB
admet-1437	495	21	the	the	DET
admet-1437	495	22	dissolution	dissolution	ADJ
admet-1437	495	23	behavior	behavior	NOUN
admet-1437	495	24	of	of	ADP
admet-1437	495	25	nanocrystals	nanocrystal	NOUN
admet-1437	495	26	.	.	PUNCT
admet-1437	496	1	the	the	DET
admet-1437	496	2	developed	develop	VERB
admet-1437	496	3	numerical	numerical	PROPN
admet-1437	496	4	model	model	NOUN
admet-1437	496	5	according	accord	VERB
admet-1437	496	6	to	to	ADP
admet-1437	496	7	the	the	DET
admet-1437	496	8	noyes	noyes	PROPN
admet-1437	496	9	-	-	PUNCT
admet-1437	496	10	whitney	whitney	PROPN
admet-1437	496	11	/	/	SYM
admet-1437	496	12	nernst	nernst	PROPN
admet-1437	496	13	-	-	PUNCT
admet-1437	496	14	brunner	brunner	PROPN
admet-1437	496	15	and	and	CCONJ
admet-1437	496	16	ostwald	ostwald	NOUN
admet-1437	496	17	-	-	PUNCT
admet-1437	496	18	freundlich	freundlich	ADJ
admet-1437	496	19	equations	equation	NOUN
admet-1437	496	20	,	,	PUNCT
admet-1437	496	21	including	include	VERB
admet-1437	496	22	the	the	DET
admet-1437	496	23	plausible	plausible	ADJ
admet-1437	496	24	value	value	NOUN
admet-1437	496	25	for	for	ADP
admet-1437	496	26	interfacial	interfacial	ADJ
admet-1437	496	27	energy	energy	NOUN
admet-1437	496	28	of	of	ADP
admet-1437	496	29	30	30	NUM
admet-1437	496	30	mj	mj	NOUN
admet-1437	496	31	/	/	SYM
admet-1437	496	32	m2	m2	PROPN
admet-1437	496	33	is	be	AUX
admet-1437	496	34	conclusive	conclusive	ADJ
admet-1437	496	35	and	and	CCONJ
admet-1437	496	36	is	be	AUX
admet-1437	496	37	deemed	deem	VERB
admet-1437	496	38	to	to	PART
admet-1437	496	39	be	be	AUX
admet-1437	496	40	accurate	accurate	ADJ
admet-1437	496	41	up	up	ADP
admet-1437	496	42	to	to	PART
admet-1437	496	43	do	do	VERB
admet-1437	496	44	<	<	X
admet-1437	496	45	18	18	NUM
admet-1437	496	46	with	with	ADP
admet-1437	496	47	a	a	DET
admet-1437	496	48	reasonable	reasonable	ADJ
admet-1437	496	49	error	error	NOUN
admet-1437	496	50	of	of	ADP
admet-1437	496	51	<	<	X
admet-1437	496	52	10	10	NUM
admet-1437	496	53	%	%	NOUN
admet-1437	496	54	between	between	ADP
admet-1437	496	55	experimental	experimental	ADJ
admet-1437	496	56	and	and	CCONJ
admet-1437	496	57	calculated	calculate	VERB
admet-1437	496	58	apparent	apparent	ADJ
admet-1437	496	59	solubility	solubility	NOUN
admet-1437	496	60	for	for	ADP
admet-1437	496	61	the	the	DET
admet-1437	496	62	investigated	investigate	VERB
admet-1437	496	63	drug	drug	NOUN
admet-1437	496	64	stabilizer	stabilizer	NOUN
admet-1437	496	65	system	system	NOUN
admet-1437	496	66	.	.	PUNCT
admet-1437	497	1	the	the	DET
admet-1437	497	2	presented	present	VERB
admet-1437	497	3	numerical	numerical	PROPN
admet-1437	497	4	model	model	NOUN
admet-1437	497	5	can	can	AUX
admet-1437	497	6	be	be	AUX
admet-1437	497	7	utilized	utilize	VERB
admet-1437	497	8	to	to	PART
admet-1437	497	9	describe	describe	VERB
admet-1437	497	10	the	the	DET
admet-1437	497	11	dissolution	dissolution	ADJ
admet-1437	497	12	behavior	behavior	NOUN
admet-1437	497	13	of	of	ADP
admet-1437	497	14	other	other	ADJ
admet-1437	497	15	nanoparticulate	nanoparticulate	ADJ
admet-1437	497	16	compounds	compound	NOUN
admet-1437	497	17	.	.	PUNCT
admet-1437	498	1	to	to	PART
admet-1437	498	2	adjust	adjust	VERB
admet-1437	498	3	the	the	DET
admet-1437	498	4	model	model	NOUN
admet-1437	498	5	to	to	ADP
admet-1437	498	6	a	a	DET
admet-1437	498	7	compound	compound	NOUN
admet-1437	498	8	of	of	ADP
admet-1437	498	9	interest	interest	NOUN
admet-1437	498	10	,	,	PUNCT
admet-1437	498	11	the	the	DET
admet-1437	498	12	compound	compound	NOUN
admet-1437	498	13	-	-	PUNCT
admet-1437	498	14	specific	specific	ADJ
admet-1437	498	15	properties	property	NOUN
admet-1437	498	16	density	density	NOUN
admet-1437	498	17	,	,	PUNCT
admet-1437	498	18	molar	molar	ADJ
admet-1437	498	19	volume	volume	NOUN
admet-1437	498	20	and	and	CCONJ
admet-1437	498	21	thermodynamic	thermodynamic	ADJ
admet-1437	498	22	solubility	solubility	NOUN
admet-1437	498	23	in	in	ADP
admet-1437	498	24	the	the	DET
admet-1437	498	25	medium	medium	NOUN
admet-1437	498	26	of	of	ADP
admet-1437	498	27	interest	interest	NOUN
admet-1437	498	28	as	as	ADV
admet-1437	498	29	well	well	ADV
admet-1437	498	30	as	as	ADP
admet-1437	498	31	the	the	DET
admet-1437	498	32	sample	sample	NOUN
admet-1437	498	33	-	-	PUNCT
admet-1437	498	34	specific	specific	ADJ
admet-1437	498	35	particle	particle	NOUN
admet-1437	498	36	size	size	NOUN
admet-1437	498	37	distribution	distribution	NOUN
admet-1437	498	38	,	,	PUNCT
admet-1437	498	39	are	be	AUX
admet-1437	498	40	required	require	VERB
admet-1437	498	41	.	.	PUNCT
admet-1437	499	1	in	in	ADP
admet-1437	499	2	addition	addition	NOUN
admet-1437	499	3	,	,	PUNCT
admet-1437	499	4	a	a	DET
admet-1437	499	5	few	few	ADJ
admet-1437	499	6	experimental	experimental	ADJ
admet-1437	499	7	data	datum	NOUN
admet-1437	499	8	points	point	NOUN
admet-1437	499	9	for	for	ADP
admet-1437	499	10	the	the	DET
admet-1437	499	11	apparent	apparent	ADJ
admet-1437	499	12	solubility	solubility	NOUN
admet-1437	499	13	of	of	ADP
admet-1437	499	14	samples	sample	NOUN
admet-1437	499	15	with	with	ADP
admet-1437	499	16	different	different	ADJ
admet-1437	499	17	particle	particle	NOUN
admet-1437	499	18	size	size	NOUN
admet-1437	499	19	distributions	distribution	NOUN
admet-1437	499	20	are	be	AUX
admet-1437	499	21	needed	need	VERB
admet-1437	499	22	to	to	PART
admet-1437	499	23	determine	determine	VERB
admet-1437	499	24	the	the	DET
admet-1437	499	25	interfacial	interfacial	ADJ
admet-1437	499	26	energy	energy	NOUN
admet-1437	499	27	by	by	ADP
admet-1437	499	28	fitting	fit	VERB
admet-1437	499	29	.	.	PUNCT
admet-1437	500	1	in	in	ADP
admet-1437	500	2	silico	silico	NOUN
admet-1437	500	3	dissolution	dissolution	NOUN
admet-1437	500	4	studies	study	NOUN
admet-1437	500	5	were	be	AUX
admet-1437	500	6	conducted	conduct	VERB
admet-1437	500	7	with	with	ADP
admet-1437	500	8	the	the	DET
admet-1437	500	9	numerical	numerical	ADJ
admet-1437	500	10	model	model	NOUN
admet-1437	500	11	for	for	ADP
admet-1437	500	12	selected	select	VERB
admet-1437	500	13	in	in	ADP
admet-1437	500	14	vivo	vivo	NOUN
admet-1437	500	15	and	and	CCONJ
admet-1437	500	16	in	in	ADP
admet-1437	500	17	vitro	vitro	X
admet-1437	500	18	scenarios	scenario	NOUN
admet-1437	500	19	to	to	PART
admet-1437	500	20	simulate	simulate	VERB
admet-1437	500	21	the	the	DET
admet-1437	500	22	complex	complex	ADJ
admet-1437	500	23	interplay	interplay	NOUN
admet-1437	500	24	between	between	ADP
admet-1437	500	25	drug	drug	NOUN
admet-1437	500	26	nanocrystal	nanocrystal	ADJ
admet-1437	500	27	particle	particle	NOUN
admet-1437	500	28	size	size	NOUN
admet-1437	500	29	distribution	distribution	NOUN
admet-1437	500	30	,	,	PUNCT
admet-1437	500	31	drug	drug	NOUN
admet-1437	500	32	amount	amount	NOUN
admet-1437	500	33	,	,	PUNCT
admet-1437	500	34	dissolution	dissolution	ADJ
admet-1437	500	35	media	medium	NOUN
admet-1437	500	36	and	and	CCONJ
admet-1437	500	37	volume	volume	NOUN
admet-1437	500	38	,	,	PUNCT
admet-1437	500	39	and	and	CCONJ
admet-1437	500	40	resulting	result	VERB
admet-1437	500	41	temporal	temporal	ADJ
admet-1437	500	42	progression	progression	NOUN
admet-1437	500	43	of	of	ADP
admet-1437	500	44	concentration	concentration	NOUN
admet-1437	500	45	during	during	ADP
admet-1437	500	46	dissolution	dissolution	NOUN
admet-1437	500	47	up	up	ADP
admet-1437	500	48	to	to	ADP
admet-1437	500	49	equilibrium	equilibrium	NOUN
admet-1437	500	50	state	state	NOUN
admet-1437	500	51	as	as	ADV
admet-1437	500	52	well	well	ADV
admet-1437	500	53	as	as	ADP
admet-1437	500	54	remaining	remaining	ADJ
admet-1437	500	55	drug	drug	NOUN
admet-1437	500	56	particle	particle	NOUN
admet-1437	500	57	size	size	NOUN
admet-1437	500	58	distribution	distribution	NOUN
admet-1437	500	59	,	,	PUNCT
admet-1437	500	60	if	if	SCONJ
admet-1437	500	61	any	any	PRON
admet-1437	500	62	.	.	PUNCT
admet-1437	501	1	it	it	PRON
admet-1437	501	2	has	have	AUX
admet-1437	501	3	been	be	AUX
admet-1437	501	4	shown	show	VERB
admet-1437	501	5	that	that	SCONJ
admet-1437	501	6	ultrafine	ultrafine	ADJ
admet-1437	501	7	drug	drug	NOUN
admet-1437	501	8	nanocrystal	nanocrystal	ADJ
admet-1437	501	9	particle	particle	NOUN
admet-1437	501	10	sizes	size	NOUN
admet-1437	501	11	result	result	VERB
admet-1437	501	12	in	in	ADP
admet-1437	501	13	rapid	rapid	ADJ
admet-1437	501	14	dissolution	dissolution	NOUN
admet-1437	501	15	kinetics	kinetic	NOUN
admet-1437	501	16	,	,	PUNCT
admet-1437	501	17	caused	cause	VERB
admet-1437	501	18	by	by	ADP
admet-1437	501	19	increased	increase	VERB
admet-1437	501	20	specific	specific	ADJ
admet-1437	501	21	surface	surface	NOUN
admet-1437	501	22	area	area	NOUN
admet-1437	501	23	and	and	CCONJ
admet-1437	501	24	increased	increase	VERB
admet-1437	501	25	apparent	apparent	ADJ
admet-1437	501	26	solubility	solubility	NOUN
admet-1437	501	27	,	,	PUNCT
admet-1437	501	28	and	and	CCONJ
admet-1437	501	29	in	in	ADP
admet-1437	501	30	reaching	reach	VERB
admet-1437	501	31	an	an	DET
admet-1437	501	32	almost	almost	ADV
admet-1437	501	33	instantaneously	instantaneously	ADV
admet-1437	501	34	equilibrium	equilibrium	NOUN
admet-1437	501	35	state	state	NOUN
admet-1437	501	36	after	after	ADP
admet-1437	501	37	only	only	ADV
admet-1437	501	38	a	a	DET
admet-1437	501	39	few	few	ADJ
admet-1437	501	40	seconds	second	NOUN
admet-1437	501	41	.	.	PUNCT
admet-1437	502	1	the	the	DET
admet-1437	502	2	highest	high	ADJ
admet-1437	502	3	equilibrium	equilibrium	NOUN
admet-1437	502	4	concentrations	concentration	NOUN
admet-1437	502	5	are	be	AUX
admet-1437	502	6	obtained	obtain	VERB
admet-1437	502	7	for	for	ADP
admet-1437	502	8	do	do	AUX
admet-1437	502	9	>	>	X
admet-1437	502	10	>	>	X
admet-1437	502	11	1	1	NUM
admet-1437	502	12	and	and	CCONJ
admet-1437	502	13	ultrafine	ultrafine	NOUN
admet-1437	502	14	drug	drug	NOUN
admet-1437	502	15	nanocrystal	nanocrystal	ADJ
admet-1437	502	16	particle	particle	NOUN
admet-1437	502	17	size	size	NOUN
admet-1437	502	18	distributions	distribution	NOUN
admet-1437	502	19	.	.	PUNCT
admet-1437	503	1	the	the	DET
admet-1437	503	2	numerical	numerical	PROPN
admet-1437	503	3	model	model	PROPN
admet-1437	503	4	offers	offer	VERB
admet-1437	503	5	the	the	DET
admet-1437	503	6	possibility	possibility	NOUN
admet-1437	503	7	to	to	PART
admet-1437	503	8	easily	easily	ADV
admet-1437	503	9	calculate	calculate	VERB
admet-1437	503	10	and	and	CCONJ
admet-1437	503	11	flexibly	flexibly	ADV
admet-1437	503	12	adjust	adjust	VERB
admet-1437	503	13	the	the	DET
admet-1437	503	14	scenario	scenario	NOUN
admet-1437	503	15	to	to	ADP
admet-1437	503	16	any	any	PRON
admet-1437	503	17	in	in	ADP
admet-1437	503	18	vivo	vivo	NOUN
admet-1437	503	19	and	and	CCONJ
admet-1437	503	20	in	in	ADP
admet-1437	503	21	vitro	vitro	X
admet-1437	503	22	application	application	NOUN
admet-1437	503	23	of	of	ADP
admet-1437	503	24	interest	interest	NOUN
admet-1437	503	25	.	.	PUNCT
admet-1437	504	1	the	the	DET
admet-1437	504	2	calculated	calculate	VERB
admet-1437	504	3	results	result	NOUN
admet-1437	504	4	illustrate	illustrate	VERB
admet-1437	504	5	the	the	DET
admet-1437	504	6	impact	impact	NOUN
admet-1437	504	7	of	of	ADP
admet-1437	504	8	the	the	DET
admet-1437	504	9	configurable	configurable	ADJ
admet-1437	504	10	formulation	formulation	NOUN
admet-1437	504	11	variables	variable	VERB
admet-1437	504	12	nanocrystal	nanocrystal	ADJ
admet-1437	504	13	particle	particle	NOUN
admet-1437	504	14	size	size	NOUN
admet-1437	504	15	distribution	distribution	NOUN
admet-1437	504	16	and	and	CCONJ
admet-1437	504	17	dose	dose	NOUN
admet-1437	504	18	strength	strength	NOUN
admet-1437	504	19	on	on	ADP
admet-1437	504	20	the	the	DET
admet-1437	504	21	obtained	obtain	VERB
admet-1437	504	22	dissolution	dissolution	NOUN
admet-1437	504	23	kinetics	kinetic	NOUN
admet-1437	504	24	and	and	CCONJ
admet-1437	504	25	supersaturation	supersaturation	NOUN
admet-1437	504	26	level	level	NOUN
admet-1437	504	27	in	in	ADP
admet-1437	504	28	a	a	DET
admet-1437	504	29	given	give	VERB
admet-1437	504	30	dissolution	dissolution	NOUN
admet-1437	504	31	medium	medium	NOUN
admet-1437	504	32	and	and	CCONJ
admet-1437	504	33	volume	volume	NOUN
admet-1437	504	34	.	.	PUNCT
admet-1437	505	1	this	this	PRON
admet-1437	505	2	is	be	AUX
admet-1437	505	3	of	of	ADP
admet-1437	505	4	vital	vital	ADJ
admet-1437	505	5	importance	importance	NOUN
admet-1437	505	6	for	for	ADP
admet-1437	505	7	industrial	industrial	ADJ
admet-1437	505	8	product	product	NOUN
admet-1437	505	9	and	and	CCONJ
admet-1437	505	10	dissolution	dissolution	NOUN
admet-1437	505	11	method	method	NOUN
admet-1437	505	12	development	development	NOUN
admet-1437	505	13	since	since	SCONJ
admet-1437	505	14	increased	increase	VERB
admet-1437	505	15	dissolution	dissolution	ADJ
admet-1437	505	16	kinetics	kinetic	NOUN
admet-1437	505	17	and	and	CCONJ
admet-1437	505	18	supersaturation	supersaturation	NOUN
admet-1437	505	19	are	be	AUX
admet-1437	505	20	generally	generally	ADV
admet-1437	505	21	accepted	accept	VERB
admet-1437	505	22	contributing	contribute	VERB
admet-1437	505	23	factors	factor	NOUN
admet-1437	505	24	for	for	ADP
admet-1437	505	25	potential	potential	ADJ
admet-1437	505	26	oral	oral	ADJ
admet-1437	505	27	bioavailability	bioavailability	NOUN
admet-1437	505	28	improvement	improvement	NOUN
admet-1437	505	29	.	.	PUNCT
admet-1437	506	1	acknowledgements	acknowledgement	NOUN
admet-1437	506	2	:	:	PUNCT
admet-1437	506	3	the	the	DET
admet-1437	506	4	authors	author	NOUN
admet-1437	506	5	would	would	AUX
admet-1437	506	6	like	like	VERB
admet-1437	506	7	to	to	PART
admet-1437	506	8	express	express	VERB
admet-1437	506	9	their	their	PRON
admet-1437	506	10	gratitude	gratitude	NOUN
admet-1437	506	11	for	for	ADP
admet-1437	506	12	experimental	experimental	ADJ
admet-1437	506	13	support	support	NOUN
admet-1437	506	14	to	to	ADP
admet-1437	506	15	armin	armin	PROPN
admet-1437	506	16	katzenstein	katzenstein	PROPN
admet-1437	506	17	,	,	PUNCT
admet-1437	506	18	dirk	dirk	PROPN
admet-1437	506	19	maertin	maertin	PROPN
admet-1437	506	20	,	,	PUNCT
admet-1437	506	21	eugen	eugen	PROPN
admet-1437	506	22	fink	fink	PROPN
admet-1437	506	23	,	,	PUNCT
admet-1437	506	24	jasmin	jasmin	PROPN
admet-1437	506	25	muminović	muminović	PROPN
admet-1437	506	26	,	,	PUNCT
admet-1437	506	27	mandy	mandy	PROPN
admet-1437	506	28	broda	broda	PROPN
admet-1437	506	29	and	and	CCONJ
admet-1437	506	30	saša	saša	VERB
admet-1437	506	31	jović	jović	PROPN
admet-1437	506	32	,	,	PUNCT
admet-1437	506	33	all	all	PRON
admet-1437	506	34	associated	associate	VERB
admet-1437	506	35	with	with	ADP
admet-1437	506	36	novartis	novartis	PROPN
admet-1437	506	37	pharma	pharma	PROPN
admet-1437	506	38	ag	ag	PROPN
admet-1437	506	39	.	.	PROPN
admet-1437	506	40	dr	dr	PROPN
admet-1437	506	41	.	.	PROPN
admet-1437	506	42	isabelle	isabelle	PROPN
admet-1437	506	43	gallou	gallou	PROPN
admet-1437	506	44	and	and	CCONJ
admet-1437	506	45	karin	karin	PROPN
admet-1437	506	46	rapp	rapp	PROPN
admet-1437	506	47	from	from	ADP
admet-1437	506	48	novartis	novartis	PROPN
admet-1437	506	49	pharma	pharma	PROPN
admet-1437	506	50	ag	ag	PROPN
admet-1437	506	51	are	be	AUX
admet-1437	506	52	acknowledged	acknowledge	VERB
admet-1437	506	53	for	for	ADP
admet-1437	506	54	their	their	PRON
admet-1437	506	55	general	general	ADJ
admet-1437	506	56	support	support	NOUN
admet-1437	506	57	.	.	PUNCT
admet-1437	507	1	conflict	conflict	NOUN
admet-1437	507	2	of	of	ADP
admet-1437	507	3	interest	interest	NOUN
admet-1437	507	4	:	:	PUNCT
admet-1437	507	5	the	the	DET
admet-1437	507	6	authors	author	NOUN
admet-1437	507	7	declare	declare	VERB
admet-1437	507	8	no	no	DET
admet-1437	507	9	conflict	conflict	NOUN
admet-1437	507	10	of	of	ADP
admet-1437	507	11	interest	interest	NOUN
admet-1437	507	12	.	.	PUNCT
admet-1437	508	1	abbreviations	abbreviation	NOUN
admet-1437	508	2	α	α	X
admet-1437	508	3	,	,	PUNCT
admet-1437	508	4	β	β	X
admet-1437	508	5	,	,	PUNCT
admet-1437	508	6	γ	γ	X
admet-1437	508	7	angles	angle	NOUN
admet-1437	508	8	of	of	ADP
admet-1437	508	9	the	the	DET
admet-1437	508	10	unit	unit	NOUN
admet-1437	508	11	cell	cell	NOUN
admet-1437	508	12	’s	’s	PART
admet-1437	508	13	axis	axis	PROPN
admet-1437	508	14	δ	δ	PROPN
admet-1437	508	15	diffusion	diffusion	NOUN
admet-1437	508	16	boundary	boundary	ADJ
admet-1437	508	17	layer	layer	NOUN
admet-1437	508	18	thickness	thickness	PROPN
admet-1437	508	19	η	η	PROPN
admet-1437	508	20	dynamic	dynamic	ADJ
admet-1437	508	21	viscosity	viscosity	NOUN
admet-1437	508	22	of	of	ADP
admet-1437	508	23	the	the	DET
admet-1437	508	24	liquid	liquid	ADJ
admet-1437	508	25	ρ	ρ	PROPN
admet-1437	508	26	density	density	NOUN
admet-1437	508	27	σ	σ	PROPN
admet-1437	508	28	standard	standard	ADJ
admet-1437	508	29	deviation	deviation	NOUN
admet-1437	508	30	admet	admet	PROPN
admet-1437	508	31	&	&	CCONJ
admet-1437	508	32	dmpk	dmpk	PROPN
admet-1437	508	33	10(4	10(4	NUM
admet-1437	508	34	)	)	PUNCT
admet-1437	508	35	(	(	PUNCT
admet-1437	508	36	2022	2022	NUM
admet-1437	508	37	)	)	PUNCT
admet-1437	508	38	253	253	NUM
admet-1437	508	39	-	-	SYM
admet-1437	508	40	287	287	NUM
admet-1437	508	41	modeling	modeling	NOUN
admet-1437	508	42	of	of	ADP
admet-1437	508	43	drug	drug	NOUN
admet-1437	508	44	nanocrystals	nanocrystal	NOUN
admet-1437	508	45	dissolution	dissolution	NOUN
admet-1437	508	46	doi	doi	PROPN
admet-1437	508	47	:	:	PUNCT
admet-1437	508	48	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	508	49	281	281	NUM
admet-1437	508	50	σsl	σsl	ADJ
admet-1437	508	51	interfacial	interfacial	ADJ
admet-1437	508	52	energy	energy	NOUN
admet-1437	508	53	between	between	ADP
admet-1437	508	54	solid	solid	ADJ
admet-1437	508	55	and	and	CCONJ
admet-1437	508	56	liquid	liquid	ADJ
admet-1437	508	57	phase	phase	NOUN
admet-1437	508	58	a	a	DET
admet-1437	508	59	,	,	PUNCT
admet-1437	508	60	b	b	NOUN
admet-1437	508	61	,	,	PUNCT
admet-1437	508	62	c	c	X
admet-1437	508	63	length	length	NOUN
admet-1437	508	64	of	of	ADP
admet-1437	508	65	the	the	DET
admet-1437	508	66	unit	unit	NOUN
admet-1437	508	67	cells	cell	NOUN
admet-1437	508	68	axis	axis	VERB
admet-1437	508	69	a	a	DET
admet-1437	508	70	surface	surface	NOUN
admet-1437	508	71	area	area	NOUN
admet-1437	508	72	am	be	AUX
admet-1437	508	73	amount	amount	NOUN
admet-1437	508	74	of	of	ADP
admet-1437	508	75	amorphous	amorphous	ADJ
admet-1437	508	76	surface	surface	NOUN
admet-1437	508	77	layer	layer	NOUN
admet-1437	508	78	cl	cl	NOUN
admet-1437	508	79	concentration	concentration	NOUN
admet-1437	508	80	in	in	ADP
admet-1437	508	81	the	the	DET
admet-1437	508	82	liquid	liquid	ADJ
admet-1437	508	83	phase	phase	NOUN
admet-1437	508	84	cps	cps	NOUN
admet-1437	508	85	counts	count	NOUN
admet-1437	508	86	per	per	ADP
admet-1437	508	87	second	second	ADJ
admet-1437	508	88	d	d	NOUN
admet-1437	508	89	diffusion	diffusion	NOUN
admet-1437	508	90	coefficient	coefficient	NOUN
admet-1437	508	91	dcell	dcell	NOUN
admet-1437	508	92	diameter	diameter	NOUN
admet-1437	508	93	of	of	ADP
admet-1437	508	94	the	the	DET
admet-1437	508	95	crystallographic	crystallographic	ADJ
admet-1437	508	96	unit	unit	NOUN
admet-1437	508	97	cell	cell	NOUN
admet-1437	508	98	do	do	AUX
admet-1437	508	99	dose	dose	VERB
admet-1437	508	100	number	number	NOUN
admet-1437	508	101	,	,	PUNCT
admet-1437	508	102	ratio	ratio	NOUN
admet-1437	508	103	of	of	ADP
admet-1437	508	104	available	available	ADJ
admet-1437	508	105	solids	solid	NOUN
admet-1437	508	106	to	to	ADP
admet-1437	508	107	thermodynamically	thermodynamically	ADV
admet-1437	508	108	soluble	soluble	ADJ
admet-1437	508	109	amount	amount	NOUN
admet-1437	508	110	i	i	PRON
admet-1437	508	111	index	index	NOUN
admet-1437	508	112	,	,	PUNCT
admet-1437	508	113	number	number	NOUN
admet-1437	508	114	of	of	ADP
admet-1437	508	115	particle	particle	NOUN
admet-1437	508	116	class	class	PROPN
admet-1437	508	117	j	j	PROPN
admet-1437	508	118	index	index	NOUN
admet-1437	508	119	,	,	PUNCT
admet-1437	508	120	number	number	NOUN
admet-1437	508	121	of	of	ADP
admet-1437	508	122	iterations	iteration	NOUN
admet-1437	508	123	kb	kb	PROPN
admet-1437	508	124	boltzmann	boltzmann	PROPN
admet-1437	508	125	constant	constant	PROPN
admet-1437	508	126	m	m	PROPN
admet-1437	508	127	mass	mass	PROPN
admet-1437	508	128	nist	nist	PROPN
admet-1437	508	129	national	national	PROPN
admet-1437	508	130	institute	institute	PROPN
admet-1437	508	131	of	of	ADP
admet-1437	508	132	standards	standard	NOUN
admet-1437	508	133	and	and	CCONJ
admet-1437	508	134	technology	technology	NOUN
admet-1437	508	135	r	r	NOUN
admet-1437	508	136	particle	particle	NOUN
admet-1437	508	137	radius	radius	NOUN
admet-1437	508	138	r	r	NOUN
admet-1437	508	139	universal	universal	ADJ
admet-1437	508	140	gas	gas	NOUN
admet-1437	508	141	constant	constant	ADJ
admet-1437	508	142	r0	r0	NOUN
admet-1437	508	143	hydrodynamic	hydrodynamic	ADJ
admet-1437	508	144	radius	radius	NOUN
admet-1437	508	145	of	of	ADP
admet-1437	508	146	diffusing	diffuse	VERB
admet-1437	508	147	particles	particle	NOUN
admet-1437	508	148	s	s	PART
admet-1437	508	149	solubility	solubility	NOUN
admet-1437	508	150	s0	s0	PROPN
admet-1437	508	151	thermodynamic	thermodynamic	PROPN
admet-1437	508	152	solubility	solubility	PROPN
admet-1437	508	153	sapp	sapp	PROPN
admet-1437	508	154	apparent	apparent	PROPN
admet-1437	508	155	solubility	solubility	PROPN
admet-1437	508	156	sapp	sapp	PROPN
admet-1437	508	157	,	,	PUNCT
admet-1437	508	158	exp	exp	NOUN
admet-1437	508	159	experimentally	experimentally	ADV
admet-1437	508	160	determined	determine	VERB
admet-1437	508	161	apparent	apparent	ADJ
admet-1437	508	162	solubility	solubility	NOUN
admet-1437	508	163	sapp	sapp	PROPN
admet-1437	508	164	,	,	PUNCT
admet-1437	508	165	th	th	X
admet-1437	508	166	theoretical	theoretical	NOUN
admet-1437	508	167	,	,	PUNCT
admet-1437	508	168	calculated	calculate	VERB
admet-1437	508	169	apparent	apparent	ADJ
admet-1437	508	170	solubility	solubility	NOUN
admet-1437	508	171	srm	srm	PROPN
admet-1437	508	172	standard	standard	ADJ
admet-1437	508	173	reference	reference	NOUN
admet-1437	508	174	material	material	NOUN
admet-1437	508	175	t	t	PROPN
admet-1437	508	176	time	time	NOUN
admet-1437	508	177	δt	δt	ADP
admet-1437	508	178	time	time	NOUN
admet-1437	508	179	step	step	NOUN
admet-1437	508	180	t	t	PROPN
admet-1437	508	181	temperature	temperature	NOUN
admet-1437	508	182	vcell	vcell	NOUN
admet-1437	508	183	volume	volume	NOUN
admet-1437	508	184	of	of	ADP
admet-1437	508	185	one	one	NUM
admet-1437	508	186	unit	unit	NOUN
admet-1437	508	187	cell	cell	NOUN
admet-1437	508	188	vl	vl	NOUN
admet-1437	508	189	volume	volume	NOUN
admet-1437	508	190	of	of	ADP
admet-1437	508	191	the	the	DET
admet-1437	508	192	liquid	liquid	ADJ
admet-1437	508	193	vm	vm	PROPN
admet-1437	508	194	molar	molar	ADJ
admet-1437	508	195	volume	volume	NOUN
admet-1437	508	196	of	of	ADP
admet-1437	508	197	dissolving	dissolve	VERB
admet-1437	508	198	compound	compound	NOUN
admet-1437	508	199	wamorph	wamorph	NOUN
admet-1437	508	200	,	,	PUNCT
admet-1437	508	201	xrpd	xrpd	PROPN
admet-1437	508	202	calculated	calculate	VERB
admet-1437	508	203	amorphous	amorphous	ADJ
admet-1437	508	204	content	content	NOUN
admet-1437	508	205	by	by	ADP
admet-1437	508	206	xrpd	xrpd	PROPN
admet-1437	508	207	measurement	measurement	PROPN
admet-1437	508	208	wcryst	wcryst	PROPN
admet-1437	508	209	,	,	PUNCT
admet-1437	508	210	xrpd	xrpd	PROPN
admet-1437	508	211	calculated	calculate	VERB
admet-1437	508	212	crystalline	crystalline	NOUN
admet-1437	508	213	content	content	NOUN
admet-1437	508	214	by	by	ADP
admet-1437	508	215	xrpd	xrpd	PROPN
admet-1437	508	216	measurement	measurement	PROPN
admet-1437	508	217	wamorph	wamorph	PROPN
admet-1437	508	218	,	,	PUNCT
admet-1437	508	219	z	z	PROPN
admet-1437	508	220	calculated	calculate	VERB
admet-1437	508	221	amorphous	amorphous	ADJ
admet-1437	508	222	content	content	NOUN
admet-1437	508	223	for	for	ADP
admet-1437	508	224	number	number	NOUN
admet-1437	508	225	of	of	ADP
admet-1437	508	226	layers	layer	NOUN
admet-1437	508	227	of	of	ADP
admet-1437	508	228	unit	unit	NOUN
admet-1437	508	229	cells	cell	NOUN
admet-1437	508	230	by	by	ADP
admet-1437	508	231	model	model	NOUN
admet-1437	508	232	x	x	PUNCT
admet-1437	508	233	particle	particle	NOUN
admet-1437	508	234	size	size	NOUN
admet-1437	508	235	y	y	PROPN
admet-1437	508	236	number	number	NOUN
admet-1437	508	237	of	of	ADP
admet-1437	508	238	particle	particle	NOUN
admet-1437	508	239	size	size	NOUN
admet-1437	508	240	classes	class	NOUN
admet-1437	508	241	that	that	PRON
admet-1437	508	242	can	can	AUX
admet-1437	508	243	further	far	ADV
admet-1437	508	244	dissolve	dissolve	VERB
admet-1437	508	245	z	z	PROPN
admet-1437	508	246	depths	depth	NOUN
admet-1437	508	247	of	of	ADP
admet-1437	508	248	amorphous	amorphous	ADJ
admet-1437	508	249	surface	surface	NOUN
admet-1437	508	250	layer	layer	NOUN
admet-1437	508	251	,	,	PUNCT
admet-1437	508	252	expressed	express	VERB
admet-1437	508	253	in	in	ADP
admet-1437	508	254	layers	layer	NOUN
admet-1437	508	255	of	of	ADP
admet-1437	508	256	unit	unit	NOUN
admet-1437	508	257	cells	cell	NOUN
admet-1437	508	258	references	reference	NOUN
admet-1437	508	259	[	[	X
admet-1437	508	260	1	1	NUM
admet-1437	508	261	]	]	X
admet-1437	508	262	b.r	b.r	PROPN
admet-1437	508	263	.	.	PROPN
admet-1437	508	264	rabinow	rabinow	PROPN
admet-1437	508	265	.	.	PUNCT
admet-1437	509	1	nanosuspensions	nanosuspension	NOUN
admet-1437	509	2	in	in	ADP
admet-1437	509	3	drug	drug	NOUN
admet-1437	509	4	delivery	delivery	NOUN
admet-1437	509	5	.	.	PUNCT
admet-1437	510	1	nature	nature	NOUN
admet-1437	510	2	reviews	review	VERB
admet-1437	510	3	drug	drug	NOUN
admet-1437	510	4	discovery	discovery	NOUN
admet-1437	510	5	3	3	NUM
admet-1437	510	6	(	(	PUNCT
admet-1437	510	7	2004	2004	NUM
admet-1437	510	8	)	)	PUNCT
admet-1437	510	9	785	785	NUM
admet-1437	510	10	-	-	SYM
admet-1437	510	11	795	795	NUM
admet-1437	510	12	.	.	PUNCT
admet-1437	511	1	https://doi.org/10.1038/nrd1494	https://doi.org/10.1038/nrd1494	NOUN
admet-1437	511	2	.	.	PUNCT
admet-1437	512	1	[	[	X
admet-1437	512	2	2	2	X
admet-1437	512	3	]	]	X
admet-1437	512	4	e.m	e.m	PROPN
admet-1437	512	5	.	.	PROPN
admet-1437	512	6	liversidge	liversidge	PROPN
admet-1437	512	7	,	,	PUNCT
admet-1437	512	8	g.g	g.g	PROPN
admet-1437	512	9	.	.	PROPN
admet-1437	512	10	liversidge	liversidge	PROPN
admet-1437	512	11	,	,	PUNCT
admet-1437	512	12	e.r	e.r	PROPN
admet-1437	512	13	.	.	PROPN
admet-1437	512	14	cooper	cooper	PROPN
admet-1437	512	15	.	.	PUNCT
admet-1437	513	1	nanosizing	nanosizing	NOUN
admet-1437	513	2	:	:	PUNCT
admet-1437	513	3	a	a	DET
admet-1437	513	4	formulation	formulation	NOUN
admet-1437	513	5	approach	approach	NOUN
admet-1437	513	6	for	for	ADP
admet-1437	513	7	poorly	poorly	ADV
admet-1437	513	8	-	-	PUNCT
admet-1437	513	9	watersoluble	watersoluble	ADJ
admet-1437	513	10	compounds	compound	NOUN
admet-1437	513	11	.	.	PUNCT
admet-1437	514	1	european	european	ADJ
admet-1437	514	2	journal	journal	PROPN
admet-1437	514	3	of	of	ADP
admet-1437	514	4	pharmaceutical	pharmaceutical	PROPN
admet-1437	514	5	sciences	science	NOUN
admet-1437	514	6	18	18	NUM
admet-1437	514	7	(	(	PUNCT
admet-1437	514	8	2003	2003	NUM
admet-1437	514	9	)	)	PUNCT
admet-1437	514	10	113	113	NUM
admet-1437	514	11	-	-	SYM
admet-1437	514	12	120	120	NUM
admet-1437	514	13	.	.	PUNCT
admet-1437	515	1	https://doi.org/10.1016/s0928-0987(02)00251-8	https://doi.org/10.1016/s0928-0987(02)00251-8	PROPN
admet-1437	515	2	.	.	PUNCT
admet-1437	516	1	[	[	X
admet-1437	516	2	3	3	NUM
admet-1437	516	3	]	]	X
admet-1437	516	4	f.	f.	PROPN
admet-1437	516	5	kesisoglou	kesisoglou	PROPN
admet-1437	516	6	,	,	PUNCT
admet-1437	516	7	s.	s.	PROPN
admet-1437	516	8	panmai	panmai	PROPN
admet-1437	516	9	,	,	PUNCT
admet-1437	516	10	y.	y.	PROPN
admet-1437	516	11	wu	wu	PROPN
admet-1437	516	12	.	.	PUNCT
admet-1437	517	1	nanosizing	nanosizing	NOUN
admet-1437	517	2	–	–	PUNCT
admet-1437	517	3	oral	oral	ADJ
admet-1437	517	4	formulation	formulation	NOUN
admet-1437	517	5	development	development	NOUN
admet-1437	517	6	and	and	CCONJ
admet-1437	517	7	biopharmaceutical	biopharmaceutical	NOUN
admet-1437	517	8	evaluation	evaluation	NOUN
admet-1437	517	9	.	.	PUNCT
admet-1437	518	1	advanced	advanced	ADJ
admet-1437	518	2	drug	drug	NOUN
admet-1437	518	3	delivery	delivery	NOUN
admet-1437	518	4	reviews	review	VERB
admet-1437	518	5	59	59	NUM
admet-1437	518	6	(	(	PUNCT
admet-1437	518	7	2007	2007	NUM
admet-1437	518	8	)	)	PUNCT
admet-1437	518	9	631	631	NUM
admet-1437	518	10	-	-	SYM
admet-1437	518	11	644	644	NUM
admet-1437	518	12	.	.	PUNCT
admet-1437	519	1	https://doi.org/10.1016/j.addr.2007.05.003	https://doi.org/10.1016/j.addr.2007.05.003	PROPN
admet-1437	519	2	.	.	PUNCT
admet-1437	520	1	[	[	X
admet-1437	520	2	4	4	X
admet-1437	520	3	]	]	PUNCT
admet-1437	520	4	j.	j.	PROPN
admet-1437	520	5	wong	wong	PROPN
admet-1437	520	6	,	,	PUNCT
admet-1437	520	7	a.	a.	NOUN
admet-1437	520	8	brugger	brugger	PROPN
admet-1437	520	9	,	,	PUNCT
admet-1437	520	10	a.	a.	PROPN
admet-1437	520	11	khare	khare	PROPN
admet-1437	520	12	,	,	PUNCT
admet-1437	520	13	m.	m.	NOUN
admet-1437	520	14	chaubal	chaubal	PROPN
admet-1437	520	15	,	,	PUNCT
admet-1437	520	16	p.	p.	PROPN
admet-1437	520	17	papadopoulos	papadopoulos	PROPN
admet-1437	520	18	,	,	PUNCT
admet-1437	520	19	b.	b.	PROPN
admet-1437	520	20	rabinow	rabinow	PROPN
admet-1437	520	21	,	,	PUNCT
admet-1437	520	22	j.	j.	PROPN
admet-1437	520	23	kipp	kipp	PROPN
admet-1437	520	24	,	,	PUNCT
admet-1437	520	25	j.	j.	PROPN
admet-1437	520	26	ning	ning	PROPN
admet-1437	520	27	.	.	PUNCT
admet-1437	520	28	suspensions	suspension	NOUN
admet-1437	520	29	for	for	ADP
admet-1437	520	30	intravenous	intravenous	ADJ
admet-1437	520	31	(	(	PUNCT
admet-1437	520	32	iv	iv	X
admet-1437	520	33	)	)	PUNCT
admet-1437	520	34	injection	injection	NOUN
admet-1437	520	35	:	:	PUNCT
admet-1437	520	36	a	a	DET
admet-1437	520	37	review	review	NOUN
admet-1437	520	38	of	of	ADP
admet-1437	520	39	development	development	NOUN
admet-1437	520	40	,	,	PUNCT
admet-1437	520	41	preclinical	preclinical	ADJ
admet-1437	520	42	and	and	CCONJ
admet-1437	520	43	clinical	clinical	ADJ
admet-1437	520	44	aspects	aspect	NOUN
admet-1437	520	45	.	.	PUNCT
admet-1437	521	1	advanced	advanced	ADJ
admet-1437	521	2	drug	drug	NOUN
admet-1437	521	3	delivery	delivery	NOUN
admet-1437	521	4	reviews	review	NOUN
admet-1437	521	5	60	60	NUM
admet-1437	521	6	(	(	PUNCT
admet-1437	521	7	2008	2008	NUM
admet-1437	521	8	)	)	PUNCT
admet-1437	521	9	939	939	NUM
admet-1437	521	10	-	-	SYM
admet-1437	521	11	954	954	NUM
admet-1437	521	12	.	.	PUNCT
admet-1437	522	1	https://doi.org/10.1016/j.addr.2007.11.008	https://doi.org/10.1016/j.addr.2007.11.008	NOUN
admet-1437	522	2	.	.	PUNCT
admet-1437	523	1	[	[	X
admet-1437	523	2	5	5	NUM
admet-1437	523	3	]	]	X
admet-1437	523	4	e.m	e.m	PROPN
admet-1437	523	5	.	.	PROPN
admet-1437	523	6	liversidge	liversidge	PROPN
admet-1437	523	7	,	,	PUNCT
admet-1437	523	8	g.g	g.g	PROPN
admet-1437	523	9	.	.	PROPN
admet-1437	523	10	liversidge	liversidge	NOUN
admet-1437	523	11	.	.	PUNCT
admet-1437	524	1	nanosizing	nanosize	VERB
admet-1437	524	2	for	for	ADP
admet-1437	524	3	oral	oral	ADJ
admet-1437	524	4	and	and	CCONJ
admet-1437	524	5	parenteral	parenteral	ADJ
admet-1437	524	6	drug	drug	NOUN
admet-1437	524	7	delivery	delivery	NOUN
admet-1437	524	8	:	:	PUNCT
admet-1437	524	9	a	a	DET
admet-1437	524	10	perspective	perspective	NOUN
admet-1437	524	11	on	on	ADP
admet-1437	524	12	formulating	formulate	VERB
admet-1437	524	13	poorly	poorly	ADJ
admet-1437	524	14	-	-	PUNCT
admet-1437	524	15	water	water	NOUN
admet-1437	524	16	soluble	soluble	ADJ
admet-1437	524	17	compounds	compound	NOUN
admet-1437	524	18	using	use	VERB
admet-1437	524	19	wet	wet	ADJ
admet-1437	524	20	media	medium	NOUN
admet-1437	524	21	milling	milling	NOUN
admet-1437	524	22	technology	technology	NOUN
admet-1437	524	23	.	.	PUNCT
admet-1437	525	1	advanced	advanced	ADJ
admet-1437	525	2	drug	drug	NOUN
admet-1437	525	3	delivery	delivery	NOUN
admet-1437	525	4	reviews	review	VERB
admet-1437	525	5	63	63	NUM
admet-1437	525	6	(	(	PUNCT
admet-1437	525	7	2011	2011	NUM
admet-1437	525	8	)	)	PUNCT
admet-1437	525	9	427	427	NUM
admet-1437	525	10	-	-	SYM
admet-1437	525	11	440	440	NUM
admet-1437	525	12	.	.	PUNCT
admet-1437	526	1	https://doi.org/10.1016/j.addr.2010.12.007	https://doi.org/10.1016/j.addr.2010.12.007	PROPN
admet-1437	526	2	.	.	PUNCT
admet-1437	527	1	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	527	2	https://doi.org/10.1038/nrd1494	https://doi.org/10.1038/nrd1494	X
admet-1437	527	3	https://doi.org/10.1016/s0928-0987(02)00251-8	https://doi.org/10.1016/s0928-0987(02)00251-8	PROPN
admet-1437	527	4	https://doi.org/10.1016/s0928-0987(02)00251-8	https://doi.org/10.1016/s0928-0987(02)00251-8	PROPN
admet-1437	527	5	https://doi.org/10.1016/j.addr.2007.05.003	https://doi.org/10.1016/j.addr.2007.05.003	PROPN
admet-1437	527	6	https://doi.org/10.1016/j.addr.2007.05.003	https://doi.org/10.1016/j.addr.2007.05.003	PROPN
admet-1437	527	7	https://doi.org/10.1016/j.addr.2007.11.008	https://doi.org/10.1016/j.addr.2007.11.008	PROPN
admet-1437	527	8	https://doi.org/10.1016/j.addr.2010.12.007	https://doi.org/10.1016/j.addr.2010.12.007	VERB
admet-1437	527	9	bonhoeffer	bonhoeffer	PROPN
admet-1437	527	10	et	et	PROPN
admet-1437	527	11	al	al	PROPN
admet-1437	527	12	.	.	PROPN
admet-1437	527	13	admet	admet	PROPN
admet-1437	527	14	&	&	CCONJ
admet-1437	527	15	dmpk	dmpk	PROPN
admet-1437	527	16	10(4	10(4	NUM
admet-1437	527	17	)	)	PUNCT
admet-1437	527	18	(	(	PUNCT
admet-1437	527	19	2022	2022	NUM
admet-1437	527	20	)	)	PUNCT
admet-1437	527	21	253	253	NUM
admet-1437	527	22	-	-	SYM
admet-1437	527	23	287	287	NUM
admet-1437	527	24	282	282	NUM
admet-1437	527	25	[	[	SYM
admet-1437	527	26	6	6	NUM
admet-1437	527	27	]	]	X
admet-1437	527	28	r.h	r.h	PROPN
admet-1437	527	29	.	.	PROPN
admet-1437	527	30	müller	müller	PROPN
admet-1437	527	31	,	,	PUNCT
admet-1437	527	32	s.	s.	PROPN
admet-1437	527	33	gohla	gohla	PROPN
admet-1437	527	34	,	,	PUNCT
admet-1437	527	35	c.m	c.m	PROPN
admet-1437	527	36	.	.	PROPN
admet-1437	527	37	keck	keck	PROPN
admet-1437	527	38	.	.	PUNCT
admet-1437	528	1	state	state	NOUN
admet-1437	528	2	of	of	ADP
admet-1437	528	3	the	the	DET
admet-1437	528	4	art	art	NOUN
admet-1437	528	5	of	of	ADP
admet-1437	528	6	nanocrystals	nanocrystal	NOUN
admet-1437	528	7	–	–	PUNCT
admet-1437	528	8	special	special	ADJ
admet-1437	528	9	features	feature	NOUN
admet-1437	528	10	,	,	PUNCT
admet-1437	528	11	production	production	NOUN
admet-1437	528	12	,	,	PUNCT
admet-1437	528	13	nanotoxicology	nanotoxicology	NOUN
admet-1437	528	14	aspects	aspect	NOUN
admet-1437	528	15	and	and	CCONJ
admet-1437	528	16	intracellular	intracellular	ADJ
admet-1437	528	17	delivery	delivery	NOUN
admet-1437	528	18	.	.	PUNCT
admet-1437	529	1	european	european	ADJ
admet-1437	529	2	journal	journal	PROPN
admet-1437	529	3	of	of	ADP
admet-1437	529	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	529	5	and	and	CCONJ
admet-1437	529	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1437	529	7	78	78	NUM
admet-1437	529	8	(	(	PUNCT
admet-1437	529	9	2011	2011	NUM
admet-1437	529	10	)	)	PUNCT
admet-1437	529	11	1	1	NUM
admet-1437	529	12	-	-	SYM
admet-1437	529	13	9	9	NUM
admet-1437	529	14	.	.	PUNCT
admet-1437	530	1	https://doi.org/10.1016/j.ejpb.2011.01.007	https://doi.org/10.1016/j.ejpb.2011.01.007	PROPN
admet-1437	530	2	.	.	PUNCT
admet-1437	531	1	[	[	X
admet-1437	531	2	7	7	X
admet-1437	531	3	]	]	X
admet-1437	531	4	r.h	r.h	PROPN
admet-1437	531	5	.	.	PROPN
admet-1437	531	6	müller	müller	PROPN
admet-1437	531	7	,	,	PUNCT
admet-1437	531	8	c.m	c.m	PROPN
admet-1437	531	9	.	.	PROPN
admet-1437	531	10	keck	keck	PROPN
admet-1437	531	11	.	.	PUNCT
admet-1437	532	1	twenty	twenty	NUM
admet-1437	532	2	years	year	NOUN
admet-1437	532	3	of	of	ADP
admet-1437	532	4	drug	drug	NOUN
admet-1437	532	5	nanocrystals	nanocrystal	NOUN
admet-1437	532	6	:	:	PUNCT
admet-1437	532	7	where	where	SCONJ
admet-1437	532	8	are	be	AUX
admet-1437	532	9	we	we	PRON
admet-1437	532	10	,	,	PUNCT
admet-1437	532	11	and	and	CCONJ
admet-1437	532	12	where	where	SCONJ
admet-1437	532	13	do	do	AUX
admet-1437	532	14	we	we	PRON
admet-1437	532	15	go	go	VERB
admet-1437	532	16	?	?	PUNCT
admet-1437	533	1	european	european	ADJ
admet-1437	533	2	journal	journal	PROPN
admet-1437	533	3	of	of	ADP
admet-1437	533	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	533	5	and	and	CCONJ
admet-1437	533	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1437	533	7	80	80	NUM
admet-1437	533	8	(	(	PUNCT
admet-1437	533	9	2012	2012	NUM
admet-1437	533	10	)	)	PUNCT
admet-1437	533	11	1	1	NUM
admet-1437	533	12	-	-	SYM
admet-1437	533	13	3	3	NUM
admet-1437	533	14	.	.	NOUN
admet-1437	533	15	https://doi.org/10.1016/j.ejpb.2011.09.012	https://doi.org/10.1016/j.ejpb.2011.09.012	NOUN
admet-1437	533	16	.	.	PUNCT
admet-1437	534	1	[	[	X
admet-1437	534	2	8	8	NUM
admet-1437	534	3	]	]	X
admet-1437	534	4	d.a	d.a	PROPN
admet-1437	534	5	.	.	PROPN
admet-1437	534	6	shah	shah	PROPN
admet-1437	534	7	,	,	PUNCT
admet-1437	534	8	s.b	s.b	PROPN
admet-1437	534	9	.	.	PROPN
admet-1437	534	10	murdande	murdande	PROPN
admet-1437	534	11	,	,	PUNCT
admet-1437	534	12	r.h	r.h	PROPN
admet-1437	534	13	.	.	PROPN
admet-1437	534	14	dave	dave	PROPN
admet-1437	534	15	.	.	PUNCT
admet-1437	535	1	a	a	DET
admet-1437	535	2	review	review	NOUN
admet-1437	535	3	:	:	PUNCT
admet-1437	535	4	pharmaceutical	pharmaceutical	NOUN
admet-1437	535	5	and	and	CCONJ
admet-1437	535	6	pharmacokinetic	pharmacokinetic	ADJ
admet-1437	535	7	aspect	aspect	NOUN
admet-1437	535	8	of	of	ADP
admet-1437	535	9	nanocrystalline	nanocrystalline	ADJ
admet-1437	535	10	suspensions	suspension	NOUN
admet-1437	535	11	.	.	PUNCT
admet-1437	536	1	journal	journal	NOUN
admet-1437	536	2	of	of	ADP
admet-1437	536	3	pharmaceutical	pharmaceutical	PROPN
admet-1437	536	4	sciences	science	NOUN
admet-1437	536	5	105	105	NUM
admet-1437	536	6	(	(	PUNCT
admet-1437	536	7	2016	2016	NUM
admet-1437	536	8	)	)	PUNCT
admet-1437	536	9	10	10	NUM
admet-1437	536	10	-	-	SYM
admet-1437	536	11	24	24	NUM
admet-1437	536	12	.	.	PUNCT
admet-1437	537	1	http://dx.doi.org/10.1002/jps.24694	http://dx.doi.org/10.1002/jps.24694	PROPN
admet-1437	537	2	.	.	PUNCT
admet-1437	538	1	[	[	X
admet-1437	538	2	9	9	NUM
admet-1437	538	3	]	]	X
admet-1437	538	4	m.l	m.l	PROPN
admet-1437	538	5	.	.	PUNCT
admet-1437	538	6	chen	chen	PROPN
admet-1437	538	7	,	,	PUNCT
admet-1437	538	8	m.	m.	PROPN
admet-1437	538	9	john	john	PROPN
admet-1437	538	10	,	,	PUNCT
admet-1437	538	11	s.l	s.l	PROPN
admet-1437	538	12	.	.	PROPN
admet-1437	538	13	lee	lee	PROPN
admet-1437	538	14	,	,	PUNCT
admet-1437	538	15	k.m	k.m	PROPN
admet-1437	538	16	.	.	PROPN
admet-1437	538	17	tyner	tyner	PROPN
admet-1437	538	18	.	.	PUNCT
admet-1437	539	1	development	development	NOUN
admet-1437	539	2	considerations	consideration	NOUN
admet-1437	539	3	for	for	ADP
admet-1437	539	4	nanocrystal	nanocrystal	ADJ
admet-1437	539	5	drug	drug	NOUN
admet-1437	539	6	products	product	NOUN
admet-1437	539	7	.	.	PUNCT
admet-1437	540	1	the	the	DET
admet-1437	540	2	aaps	aaps	PROPN
admet-1437	540	3	journal	journal	PROPN
admet-1437	540	4	19	19	NUM
admet-1437	540	5	(	(	PUNCT
admet-1437	540	6	2017	2017	NUM
admet-1437	540	7	)	)	PUNCT
admet-1437	540	8	642	642	NUM
admet-1437	540	9	-	-	SYM
admet-1437	540	10	651	651	NUM
admet-1437	540	11	.	.	PUNCT
admet-1437	541	1	https://doi.org/10.1208/s12248-017-0064-x	https://doi.org/10.1208/s12248-017-0064-x	PROPN
admet-1437	541	2	.	.	PUNCT
admet-1437	542	1	[	[	X
admet-1437	542	2	10	10	NUM
admet-1437	542	3	]	]	X
admet-1437	542	4	l.	l.	PROPN
admet-1437	542	5	peltonen	peltonen	PROPN
admet-1437	542	6	,	,	PUNCT
admet-1437	542	7	c.j	c.j	PROPN
admet-1437	542	8	.	.	PROPN
admet-1437	542	9	strachan	strachan	PROPN
admet-1437	542	10	.	.	PUNCT
admet-1437	543	1	degrees	degree	NOUN
admet-1437	543	2	of	of	ADP
admet-1437	543	3	order	order	NOUN
admet-1437	543	4	:	:	PUNCT
admet-1437	543	5	a	a	DET
admet-1437	543	6	comparison	comparison	NOUN
admet-1437	543	7	of	of	ADP
admet-1437	543	8	nanocrystal	nanocrystal	ADJ
admet-1437	543	9	and	and	CCONJ
admet-1437	543	10	amorphous	amorphous	ADJ
admet-1437	543	11	solids	solid	NOUN
admet-1437	543	12	for	for	ADP
admet-1437	543	13	poorly	poorly	ADV
admet-1437	543	14	soluble	soluble	ADJ
admet-1437	543	15	drugs	drug	NOUN
admet-1437	543	16	.	.	PUNCT
admet-1437	544	1	international	international	ADJ
admet-1437	544	2	journal	journal	PROPN
admet-1437	544	3	of	of	ADP
admet-1437	544	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	544	5	586	586	NUM
admet-1437	544	6	(	(	PUNCT
admet-1437	544	7	2020	2020	NUM
admet-1437	544	8	)	)	PUNCT
admet-1437	544	9	119492	119492	NUM
admet-1437	544	10	.	.	PUNCT
admet-1437	545	1	https://doi.org/10.1016/j.ijpharm.2020.119492	https://doi.org/10.1016/j.ijpharm.2020.119492	PROPN
admet-1437	545	2	.	.	PUNCT
admet-1437	546	1	[	[	X
admet-1437	546	2	11	11	NUM
admet-1437	546	3	]	]	X
admet-1437	546	4	d.	d.	PROPN
admet-1437	546	5	dahlgren	dahlgren	PROPN
admet-1437	546	6	,	,	PUNCT
admet-1437	546	7	e.	e.	PROPN
admet-1437	546	8	sjögren	sjögren	PROPN
admet-1437	546	9	,	,	PUNCT
admet-1437	546	10	h.	h.	PROPN
admet-1437	546	11	lennernäs	lennernäs	PROPN
admet-1437	546	12	.	.	PUNCT
admet-1437	547	1	intestinal	intestinal	ADJ
admet-1437	547	2	absorption	absorption	NOUN
admet-1437	547	3	of	of	ADP
admet-1437	547	4	bcs	bcs	NOUN
admet-1437	547	5	class	class	NOUN
admet-1437	547	6	ii	ii	NOUN
admet-1437	547	7	drugs	drug	NOUN
admet-1437	547	8	administered	administer	VERB
admet-1437	547	9	as	as	ADP
admet-1437	547	10	nanoparticles	nanoparticle	NOUN
admet-1437	547	11	:	:	PUNCT
admet-1437	547	12	a	a	DET
admet-1437	547	13	review	review	NOUN
admet-1437	547	14	based	base	VERB
admet-1437	547	15	on	on	ADP
admet-1437	547	16	in	in	ADP
admet-1437	547	17	vivo	vivo	ADJ
admet-1437	547	18	data	datum	NOUN
admet-1437	547	19	from	from	ADP
admet-1437	547	20	intestinal	intestinal	ADJ
admet-1437	547	21	perfusion	perfusion	NOUN
admet-1437	547	22	models	model	NOUN
admet-1437	547	23	.	.	PUNCT
admet-1437	548	1	admet	admet	PROPN
admet-1437	548	2	&	&	CCONJ
admet-1437	548	3	dmpk	dmpk	PROPN
admet-1437	548	4	8	8	NUM
admet-1437	548	5	(	(	PUNCT
admet-1437	548	6	2020	2020	NUM
admet-1437	548	7	)	)	PUNCT
admet-1437	548	8	375	375	NUM
admet-1437	548	9	-	-	SYM
admet-1437	548	10	390	390	NUM
admet-1437	548	11	.	.	PUNCT
admet-1437	548	12	https://dx.doi.org/10.5599/admet.881	https://dx.doi.org/10.5599/admet.881	NOUN
admet-1437	548	13	.	.	PUNCT
admet-1437	549	1	[	[	X
admet-1437	549	2	12	12	NUM
admet-1437	549	3	]	]	PUNCT
admet-1437	549	4	z.	z.	PROPN
admet-1437	549	5	ma	ma	PROPN
admet-1437	549	6	,	,	PUNCT
admet-1437	549	7	h.	h.	PROPN
admet-1437	549	8	zhang	zhang	PROPN
admet-1437	549	9	,	,	PUNCT
admet-1437	549	10	y.	y.	PROPN
admet-1437	549	11	wang	wang	PROPN
admet-1437	549	12	,	,	PUNCT
admet-1437	549	13	x.	x.	PROPN
admet-1437	549	14	tang	tang	PROPN
admet-1437	549	15	.	.	PUNCT
admet-1437	550	1	development	development	NOUN
admet-1437	550	2	and	and	CCONJ
admet-1437	550	3	evaluation	evaluation	NOUN
admet-1437	550	4	of	of	ADP
admet-1437	550	5	intramuscularly	intramuscularly	ADV
admet-1437	550	6	administered	administer	VERB
admet-1437	550	7	nano	nano	NOUN
admet-1437	550	8	/	/	SYM
admet-1437	550	9	microcrystal	microcrystal	ADJ
admet-1437	550	10	suspension	suspension	NOUN
admet-1437	550	11	.	.	PUNCT
admet-1437	551	1	expert	expert	ADJ
admet-1437	551	2	opinion	opinion	NOUN
admet-1437	551	3	on	on	ADP
admet-1437	551	4	drug	drug	NOUN
admet-1437	551	5	delivery	delivery	NOUN
admet-1437	551	6	16	16	NUM
admet-1437	551	7	(	(	PUNCT
admet-1437	551	8	2019	2019	NUM
admet-1437	551	9	)	)	PUNCT
admet-1437	551	10	347	347	NUM
admet-1437	551	11	-	-	SYM
admet-1437	551	12	361	361	NUM
admet-1437	551	13	.	.	PUNCT
admet-1437	552	1	https://doi.org/10.1080/17425247.2019.1588248	https://doi.org/10.1080/17425247.2019.1588248	PUNCT
admet-1437	552	2	.	.	PUNCT
admet-1437	553	1	[	[	X
admet-1437	553	2	13	13	NUM
admet-1437	553	3	]	]	PUNCT
admet-1437	553	4	r.	r.	PROPN
admet-1437	553	5	jain	jain	PROPN
admet-1437	553	6	,	,	PUNCT
admet-1437	553	7	j.	j.	PROPN
admet-1437	553	8	meyer	meyer	PROPN
admet-1437	553	9	,	,	PUNCT
admet-1437	553	10	a.	a.	NOUN
admet-1437	553	11	wehr	wehr	PROPN
admet-1437	553	12	,	,	PUNCT
admet-1437	553	13	b.	b.	PROPN
admet-1437	553	14	rege	rege	PROPN
admet-1437	553	15	,	,	PUNCT
admet-1437	553	16	l.	l.	PROPN
admet-1437	553	17	von	von	PROPN
admet-1437	553	18	moltke	moltke	PROPN
admet-1437	553	19	,	,	PUNCT
admet-1437	553	20	p.j	p.j	PROPN
admet-1437	553	21	.	.	PROPN
admet-1437	553	22	weiden	weiden	PROPN
admet-1437	553	23	.	.	PROPN
admet-1437	554	1	size	size	NOUN
admet-1437	554	2	matters	matter	VERB
admet-1437	554	3	:	:	PUNCT
admet-1437	554	4	the	the	DET
admet-1437	554	5	importance	importance	NOUN
admet-1437	554	6	of	of	ADP
admet-1437	554	7	particle	particle	NOUN
admet-1437	554	8	size	size	NOUN
admet-1437	554	9	in	in	ADP
admet-1437	554	10	a	a	DET
admet-1437	554	11	newly	newly	ADV
admet-1437	554	12	developed	develop	VERB
admet-1437	554	13	injectable	injectable	ADJ
admet-1437	554	14	formulation	formulation	NOUN
admet-1437	554	15	for	for	ADP
admet-1437	554	16	the	the	DET
admet-1437	554	17	treatment	treatment	NOUN
admet-1437	554	18	of	of	ADP
admet-1437	554	19	schizophrenia	schizophrenia	NOUN
admet-1437	554	20	.	.	PUNCT
admet-1437	555	1	cns	cns	PROPN
admet-1437	555	2	spectrums	spectrum	NOUN
admet-1437	555	3	25	25	NUM
admet-1437	555	4	(	(	PUNCT
admet-1437	555	5	2020	2020	NUM
admet-1437	555	6	)	)	PUNCT
admet-1437	555	7	323	323	NUM
admet-1437	555	8	-	-	SYM
admet-1437	555	9	330	330	NUM
admet-1437	555	10	.	.	PUNCT
admet-1437	556	1	https://doi.org/10.1017/s1092852919000816	https://doi.org/10.1017/s1092852919000816	PROPN
admet-1437	556	2	.	.	PUNCT
admet-1437	557	1	[	[	X
admet-1437	557	2	14	14	NUM
admet-1437	557	3	]	]	X
admet-1437	557	4	w.c	w.c	PROPN
admet-1437	557	5	.	.	PROPN
admet-1437	557	6	smith	smith	PROPN
admet-1437	557	7	,	,	PUNCT
admet-1437	557	8	j.	j.	PROPN
admet-1437	557	9	bae	bae	PROPN
admet-1437	557	10	,	,	PUNCT
admet-1437	557	11	y.	y.	PROPN
admet-1437	557	12	zhang	zhang	PROPN
admet-1437	557	13	,	,	PUNCT
admet-1437	557	14	b.	b.	PROPN
admet-1437	557	15	qin	qin	PROPN
admet-1437	557	16	,	,	PUNCT
admet-1437	557	17	y.	y.	PROPN
admet-1437	557	18	wang	wang	PROPN
admet-1437	557	19	,	,	PUNCT
admet-1437	557	20	d.	d.	PROPN
admet-1437	557	21	kozak	kozak	PROPN
admet-1437	557	22	,	,	PUNCT
admet-1437	557	23	m.	m.	NOUN
admet-1437	557	24	ashraf	ashraf	PROPN
admet-1437	557	25	,	,	PUNCT
admet-1437	557	26	x.	x.	PROPN
admet-1437	557	27	xu	xu	PROPN
admet-1437	557	28	.	.	PUNCT
admet-1437	557	29	impact	impact	NOUN
admet-1437	557	30	of	of	ADP
admet-1437	557	31	particle	particle	NOUN
admet-1437	557	32	flocculation	flocculation	NOUN
admet-1437	557	33	on	on	ADP
admet-1437	557	34	the	the	DET
admet-1437	557	35	dissolution	dissolution	NOUN
admet-1437	557	36	and	and	CCONJ
admet-1437	557	37	bioavailability	bioavailability	NOUN
admet-1437	557	38	of	of	ADP
admet-1437	557	39	injectable	injectable	ADJ
admet-1437	557	40	suspensions	suspension	NOUN
admet-1437	557	41	.	.	PUNCT
admet-1437	558	1	international	international	ADJ
admet-1437	558	2	journal	journal	PROPN
admet-1437	558	3	of	of	ADP
admet-1437	558	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	558	5	604	604	NUM
admet-1437	558	6	(	(	PUNCT
admet-1437	558	7	2021	2021	NUM
admet-1437	558	8	)	)	PUNCT
admet-1437	558	9	120767	120767	NUM
admet-1437	558	10	.	.	PUNCT
admet-1437	559	1	https://doi.org/10.1016/j.ijpharm.2021.120767	https://doi.org/10.1016/j.ijpharm.2021.120767	NOUN
admet-1437	559	2	.	.	PUNCT
admet-1437	560	1	[	[	X
admet-1437	560	2	15	15	NUM
admet-1437	560	3	]	]	X
admet-1437	560	4	e.	e.	PROPN
admet-1437	560	5	merisko	merisko	PROPN
admet-1437	560	6	-	-	PUNCT
admet-1437	560	7	liversidge	liversidge	VERB
admet-1437	560	8	,	,	PUNCT
admet-1437	560	9	g.g	g.g	PROPN
admet-1437	560	10	.	.	PROPN
admet-1437	560	11	liversidge	liversidge	NOUN
admet-1437	560	12	.	.	PUNCT
admet-1437	561	1	nanosizing	nanosize	VERB
admet-1437	561	2	for	for	ADP
admet-1437	561	3	oral	oral	ADJ
admet-1437	561	4	and	and	CCONJ
admet-1437	561	5	parenteral	parenteral	ADJ
admet-1437	561	6	drug	drug	NOUN
admet-1437	561	7	delivery	delivery	NOUN
admet-1437	561	8	:	:	PUNCT
admet-1437	561	9	a	a	DET
admet-1437	561	10	perspective	perspective	NOUN
admet-1437	561	11	on	on	ADP
admet-1437	561	12	formulating	formulate	VERB
admet-1437	561	13	poorly	poorly	ADJ
admet-1437	561	14	-	-	PUNCT
admet-1437	561	15	water	water	NOUN
admet-1437	561	16	soluble	soluble	ADJ
admet-1437	561	17	compounds	compound	NOUN
admet-1437	561	18	using	use	VERB
admet-1437	561	19	wet	wet	ADJ
admet-1437	561	20	media	medium	NOUN
admet-1437	561	21	milling	milling	NOUN
admet-1437	561	22	technology	technology	NOUN
admet-1437	561	23	.	.	PUNCT
admet-1437	562	1	advanced	advanced	ADJ
admet-1437	562	2	drug	drug	NOUN
admet-1437	562	3	delivery	delivery	NOUN
admet-1437	562	4	reviews	review	VERB
admet-1437	562	5	63	63	NUM
admet-1437	562	6	(	(	PUNCT
admet-1437	562	7	2011	2011	NUM
admet-1437	562	8	)	)	PUNCT
admet-1437	562	9	427	427	NUM
admet-1437	562	10	-	-	SYM
admet-1437	562	11	440	440	NUM
admet-1437	562	12	.	.	PUNCT
admet-1437	563	1	https://doi.org/10.1016/j.addr.2010.12.007	https://doi.org/10.1016/j.addr.2010.12.007	NOUN
admet-1437	563	2	.	.	PUNCT
admet-1437	564	1	[	[	X
admet-1437	564	2	16	16	NUM
admet-1437	564	3	]	]	X
admet-1437	564	4	j.p	j.p	PROPN
admet-1437	564	5	.	.	PROPN
admet-1437	564	6	möschwitzer	möschwitzer	PROPN
admet-1437	564	7	.	.	PUNCT
admet-1437	565	1	drug	drug	NOUN
admet-1437	565	2	nanocrystals	nanocrystal	NOUN
admet-1437	565	3	in	in	ADP
admet-1437	565	4	the	the	DET
admet-1437	565	5	commercial	commercial	ADJ
admet-1437	565	6	pharmaceutical	pharmaceutical	ADJ
admet-1437	565	7	development	development	NOUN
admet-1437	565	8	process	process	NOUN
admet-1437	565	9	.	.	PUNCT
admet-1437	566	1	international	international	ADJ
admet-1437	566	2	journal	journal	PROPN
admet-1437	566	3	of	of	ADP
admet-1437	566	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	566	5	453	453	NUM
admet-1437	566	6	(	(	PUNCT
admet-1437	566	7	2013	2013	NUM
admet-1437	566	8	)	)	PUNCT
admet-1437	566	9	142	142	NUM
admet-1437	566	10	-	-	SYM
admet-1437	566	11	156	156	NUM
admet-1437	566	12	.	.	PUNCT
admet-1437	567	1	https://doi.org/10.1016/j.ijpharm.2012.09.034	https://doi.org/10.1016/j.ijpharm.2012.09.034	PROPN
admet-1437	567	2	.	.	PUNCT
admet-1437	568	1	[	[	X
admet-1437	568	2	17	17	NUM
admet-1437	568	3	]	]	PUNCT
admet-1437	568	4	m.	m.	NOUN
admet-1437	568	5	li	li	PROPN
admet-1437	568	6	,	,	PUNCT
admet-1437	568	7	m.	m.	PROPN
admet-1437	568	8	azad	azad	PROPN
admet-1437	568	9	,	,	PUNCT
admet-1437	568	10	r.	r.	PROPN
admet-1437	568	11	dave	dave	PROPN
admet-1437	568	12	,	,	PUNCT
admet-1437	568	13	e.	e.	PROPN
admet-1437	568	14	bilgili	bilgili	PROPN
admet-1437	568	15	.	.	PUNCT
admet-1437	569	1	nanomilling	nanomille	VERB
admet-1437	569	2	of	of	ADP
admet-1437	569	3	drugs	drug	NOUN
admet-1437	569	4	for	for	ADP
admet-1437	569	5	bioavailability	bioavailability	NOUN
admet-1437	569	6	enhancement	enhancement	NOUN
admet-1437	569	7	:	:	PUNCT
admet-1437	569	8	a	a	DET
admet-1437	569	9	holistic	holistic	ADJ
admet-1437	569	10	formulation	formulation	NOUN
admet-1437	569	11	-	-	PUNCT
admet-1437	569	12	process	process	NOUN
admet-1437	569	13	perspective	perspective	NOUN
admet-1437	569	14	.	.	PUNCT
admet-1437	570	1	pharmaceutics	pharmaceutic	NOUN
admet-1437	570	2	8	8	NUM
admet-1437	570	3	(	(	PUNCT
admet-1437	570	4	2016	2016	NUM
admet-1437	570	5	)	)	PUNCT
admet-1437	570	6	17	17	NUM
admet-1437	570	7	.	.	PUNCT
admet-1437	570	8	https://doi.org/10.3390/pharmaceutics8020017	https://doi.org/10.3390/pharmaceutics8020017	PROPN
admet-1437	570	9	.	.	PUNCT
admet-1437	571	1	[	[	X
admet-1437	571	2	18	18	NUM
admet-1437	571	3	]	]	PUNCT
admet-1437	571	4	m.	m.	NOUN
admet-1437	571	5	malamatari	malamatari	PROPN
admet-1437	571	6	,	,	PUNCT
admet-1437	571	7	k.m.g	k.m.g	PROPN
admet-1437	571	8	.	.	PUNCT
admet-1437	572	1	taylor	taylor	PROPN
admet-1437	572	2	,	,	PUNCT
admet-1437	572	3	s.	s.	PROPN
admet-1437	572	4	malamataris	malamataris	PROPN
admet-1437	572	5	,	,	PUNCT
admet-1437	572	6	d.	d.	PROPN
admet-1437	572	7	douroumis	douroumis	PROPN
admet-1437	572	8	,	,	PUNCT
admet-1437	572	9	k.	k.	PROPN
admet-1437	572	10	kachrimanis	kachrimanis	PROPN
admet-1437	572	11	.	.	PUNCT
admet-1437	573	1	pharmaceutical	pharmaceutical	ADJ
admet-1437	573	2	nanocrystals	nanocrystal	NOUN
admet-1437	573	3	:	:	PUNCT
admet-1437	573	4	production	production	NOUN
admet-1437	573	5	by	by	ADP
admet-1437	573	6	wet	wet	ADJ
admet-1437	573	7	milling	milling	NOUN
admet-1437	573	8	and	and	CCONJ
admet-1437	573	9	applications	application	NOUN
admet-1437	573	10	.	.	PUNCT
admet-1437	574	1	drug	drug	NOUN
admet-1437	574	2	discovery	discovery	PROPN
admet-1437	574	3	today	today	NOUN
admet-1437	574	4	23	23	NUM
admet-1437	574	5	(	(	PUNCT
admet-1437	574	6	2018	2018	NUM
admet-1437	574	7	)	)	PUNCT
admet-1437	574	8	534	534	NUM
admet-1437	574	9	-	-	SYM
admet-1437	574	10	547	547	NUM
admet-1437	574	11	.	.	PUNCT
admet-1437	575	1	https://doi.org/10.1016/j.drudis.2018.01.016	https://doi.org/10.1016/j.drudis.2018.01.016	PROPN
admet-1437	575	2	.	.	PUNCT
admet-1437	576	1	[	[	X
admet-1437	576	2	19	19	NUM
admet-1437	576	3	]	]	X
admet-1437	576	4	l.	l.	PROPN
admet-1437	576	5	peltonen	peltonen	PROPN
admet-1437	576	6	,	,	PUNCT
admet-1437	576	7	j.	j.	PROPN
admet-1437	576	8	hirvonen	hirvonen	PROPN
admet-1437	576	9	.	.	PUNCT
admet-1437	577	1	drug	drug	NOUN
admet-1437	577	2	nanocrystals	nanocrystal	NOUN
admet-1437	577	3	–	–	PUNCT
admet-1437	577	4	versatile	versatile	ADJ
admet-1437	577	5	option	option	NOUN
admet-1437	577	6	for	for	ADP
admet-1437	577	7	formulation	formulation	NOUN
admet-1437	577	8	of	of	ADP
admet-1437	577	9	poorly	poorly	ADV
admet-1437	577	10	soluble	soluble	ADJ
admet-1437	577	11	materials	material	NOUN
admet-1437	577	12	.	.	PUNCT
admet-1437	578	1	international	international	ADJ
admet-1437	578	2	journal	journal	PROPN
admet-1437	578	3	of	of	ADP
admet-1437	578	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	578	5	537	537	NUM
admet-1437	578	6	(	(	PUNCT
admet-1437	578	7	2018	2018	NUM
admet-1437	578	8	)	)	PUNCT
admet-1437	578	9	73	73	NUM
admet-1437	578	10	-	-	SYM
admet-1437	578	11	83	83	NUM
admet-1437	578	12	.	.	PUNCT
admet-1437	579	1	https://doi.org/10.1016/j.ijpharm.2017.12.005	https://doi.org/10.1016/j.ijpharm.2017.12.005	VERB
admet-1437	579	2	.	.	PUNCT
admet-1437	580	1	[	[	X
admet-1437	580	2	20	20	NUM
admet-1437	580	3	]	]	X
admet-1437	580	4	y.	y.	PROPN
admet-1437	580	5	tanaka	tanaka	PROPN
admet-1437	580	6	,	,	PUNCT
admet-1437	580	7	m.	m.	PROPN
admet-1437	580	8	inkyo	inkyo	PROPN
admet-1437	580	9	,	,	PUNCT
admet-1437	580	10	r.	r.	PROPN
admet-1437	580	11	yumoto	yumoto	NOUN
admet-1437	580	12	,	,	PUNCT
admet-1437	580	13	j.	j.	PROPN
admet-1437	580	14	nagai	nagai	PROPN
admet-1437	580	15	,	,	PUNCT
admet-1437	580	16	m.	m.	PROPN
admet-1437	580	17	takano	takano	PROPN
admet-1437	580	18	,	,	PUNCT
admet-1437	580	19	s.	s.	PROPN
admet-1437	580	20	nagata	nagata	PROPN
admet-1437	580	21	.	.	PUNCT
admet-1437	581	1	nanoparticulation	nanoparticulation	NOUN
admet-1437	581	2	of	of	ADP
admet-1437	581	3	probucol	probucol	PROPN
admet-1437	581	4	,	,	PUNCT
admet-1437	581	5	a	a	DET
admet-1437	581	6	poorly	poorly	ADV
admet-1437	581	7	water	water	NOUN
admet-1437	581	8	-	-	PUNCT
admet-1437	581	9	soluble	soluble	ADJ
admet-1437	581	10	drug	drug	NOUN
admet-1437	581	11	,	,	PUNCT
admet-1437	581	12	using	use	VERB
admet-1437	581	13	a	a	DET
admet-1437	581	14	novel	novel	ADJ
admet-1437	581	15	wet	wet	ADJ
admet-1437	581	16	-	-	PUNCT
admet-1437	581	17	milling	mill	VERB
admet-1437	581	18	process	process	NOUN
admet-1437	581	19	to	to	PART
admet-1437	581	20	improve	improve	VERB
admet-1437	581	21	in	in	ADP
admet-1437	581	22	vitro	vitro	X
admet-1437	581	23	dissolution	dissolution	NOUN
admet-1437	581	24	and	and	CCONJ
admet-1437	581	25	in	in	ADP
admet-1437	581	26	vivo	vivo	ADJ
admet-1437	581	27	oral	oral	ADJ
admet-1437	581	28	absorption	absorption	NOUN
admet-1437	581	29	.	.	PUNCT
admet-1437	582	1	drug	drug	NOUN
admet-1437	582	2	development	development	NOUN
admet-1437	582	3	and	and	CCONJ
admet-1437	582	4	industrial	industrial	ADJ
admet-1437	582	5	pharmacy	pharmacy	NOUN
admet-1437	582	6	38	38	NUM
admet-1437	582	7	(	(	PUNCT
admet-1437	582	8	2012	2012	NUM
admet-1437	582	9	)	)	PUNCT
admet-1437	582	10	1015	1015	NUM
admet-1437	582	11	-	-	SYM
admet-1437	582	12	1023	1023	NUM
admet-1437	582	13	.	.	PUNCT
admet-1437	583	1	https://doi.org/10.3109/03639045.2011.637051	https://doi.org/10.3109/03639045.2011.637051	NOUN
admet-1437	583	2	.	.	PUNCT
admet-1437	584	1	[	[	X
admet-1437	584	2	21	21	NUM
admet-1437	584	3	]	]	PUNCT
admet-1437	584	4	m.	m.	PROPN
admet-1437	584	5	li	li	PROPN
admet-1437	584	6	,	,	PUNCT
admet-1437	584	7	n.	n.	PROPN
admet-1437	584	8	yaragudi	yaragudi	PROPN
admet-1437	584	9	,	,	PUNCT
admet-1437	584	10	a.	a.	NOUN
admet-1437	584	11	afolabi	afolabi	NOUN
admet-1437	584	12	,	,	PUNCT
admet-1437	584	13	r.	r.	PROPN
admet-1437	584	14	dave	dave	PROPN
admet-1437	584	15	,	,	PUNCT
admet-1437	584	16	e.	e.	PROPN
admet-1437	584	17	bilgili	bilgili	PROPN
admet-1437	584	18	.	.	PUNCT
admet-1437	585	1	sub-100	sub-100	PROPN
admet-1437	585	2	nm	nm	DET
admet-1437	585	3	drug	drug	NOUN
admet-1437	585	4	particle	particle	NOUN
admet-1437	585	5	suspensions	suspension	NOUN
admet-1437	585	6	prepared	prepare	VERB
admet-1437	585	7	via	via	ADP
admet-1437	585	8	wet	wet	ADJ
admet-1437	585	9	milling	milling	NOUN
admet-1437	585	10	with	with	ADP
admet-1437	585	11	low	low	ADJ
admet-1437	585	12	bead	bead	NOUN
admet-1437	585	13	contamination	contamination	NOUN
admet-1437	585	14	through	through	ADP
admet-1437	585	15	novel	novel	ADJ
admet-1437	585	16	process	process	NOUN
admet-1437	585	17	intensification	intensification	NOUN
admet-1437	585	18	.	.	PUNCT
admet-1437	586	1	chemical	chemical	NOUN
admet-1437	586	2	engineering	engineering	NOUN
admet-1437	586	3	science	science	NOUN
admet-1437	586	4	130	130	NUM
admet-1437	586	5	(	(	PUNCT
admet-1437	586	6	2015	2015	NUM
admet-1437	586	7	)	)	PUNCT
admet-1437	586	8	207.220	207.220	NUM
admet-1437	586	9	.	.	PUNCT
admet-1437	587	1	https://doi.org/10.1016/j.ces.2015.03.020	https://doi.org/10.1016/j.ces.2015.03.020	NOUN
admet-1437	587	2	.	.	PUNCT
admet-1437	588	1	[	[	X
admet-1437	588	2	22	22	NUM
admet-1437	588	3	]	]	X
admet-1437	588	4	d.	d.	PROPN
admet-1437	588	5	juenemann	juenemann	PROPN
admet-1437	588	6	,	,	PUNCT
admet-1437	588	7	e.	e.	PROPN
admet-1437	588	8	jantratid	jantratid	PROPN
admet-1437	588	9	,	,	PUNCT
admet-1437	588	10	c.	c.	PROPN
admet-1437	588	11	wagner	wagner	PROPN
admet-1437	588	12	,	,	PUNCT
admet-1437	588	13	c.	c.	PROPN
admet-1437	588	14	reppas	reppas	PROPN
admet-1437	588	15	,	,	PUNCT
admet-1437	588	16	m.	m.	NOUN
admet-1437	588	17	vertzoni	vertzoni	PROPN
admet-1437	588	18	,	,	PUNCT
admet-1437	588	19	j.b	j.b	PROPN
admet-1437	588	20	.	.	PROPN
admet-1437	588	21	dressman	dressman	PROPN
admet-1437	588	22	.	.	PUNCT
admet-1437	589	1	biorelevant	biorelevant	PROPN
admet-1437	589	2	in	in	ADP
admet-1437	589	3	vitro	vitro	X
admet-1437	589	4	dissolution	dissolution	NOUN
admet-1437	589	5	testing	testing	NOUN
admet-1437	589	6	of	of	ADP
admet-1437	589	7	products	product	NOUN
admet-1437	589	8	containing	contain	VERB
admet-1437	589	9	micronized	micronized	ADJ
admet-1437	589	10	or	or	CCONJ
admet-1437	589	11	nanosized	nanosized	ADJ
admet-1437	589	12	fenofibrate	fenofibrate	NOUN
admet-1437	589	13	with	with	ADP
admet-1437	589	14	a	a	DET
admet-1437	589	15	view	view	NOUN
admet-1437	589	16	to	to	PART
admet-1437	589	17	https://doi.org/10.1016/j.ejpb.2011.01.007	https://doi.org/10.1016/j.ejpb.2011.01.007	VERB
admet-1437	589	18	https://doi.org/10.1016/j.ejpb.2011.09.012	https://doi.org/10.1016/j.ejpb.2011.09.012	NOUN
admet-1437	589	19	https://doi.org/10.1016/j.ejpb.2011.09.012	https://doi.org/10.1016/j.ejpb.2011.09.012	NOUN
admet-1437	589	20	http://dx.doi.org/-10.1002/jps.24694	http://dx.doi.org/-10.1002/jps.24694	PROPN
admet-1437	589	21	http://dx.doi.org/-10.1002/jps.24694	http://dx.doi.org/-10.1002/jps.24694	PROPN
admet-1437	590	1	https://doi.org/10.1208/s12248-017-0064-x	https://doi.org/10.1208/s12248-017-0064-x	INTJ
admet-1437	590	2	https://doi.org/10.1016/j.ijpharm.2020.119492	https://doi.org/10.1016/j.ijpharm.2020.119492	PROPN
admet-1437	590	3	https://doi.org/10.1016/j.ijpharm.2020.119492	https://doi.org/10.1016/j.ijpharm.2020.119492	PROPN
admet-1437	590	4	https://dx.doi.org/10.5599/admet.881	https://dx.doi.org/10.5599/admet.881	NOUN
admet-1437	590	5	https://doi.org/10.1080/17425247.2019.1588248	https://doi.org/10.1080/17425247.2019.1588248	PUNCT
admet-1437	590	6	https://doi.org/10.1080/17425247.2019.1588248	https://doi.org/10.1080/17425247.2019.1588248	PUNCT
admet-1437	591	1	https://doi.org/10.1017/s1092852919000816	https://doi.org/10.1017/s1092852919000816	PROPN
admet-1437	591	2	https://doi.org/10.1016/j.ijpharm.2021.120767	https://doi.org/10.1016/j.ijpharm.2021.120767	PROPN
admet-1437	591	3	https://doi.org/10.1016/j.addr.2010.12.007	https://doi.org/10.1016/j.addr.2010.12.007	VERB
admet-1437	591	4	https://doi.org/10.1016/j.ijpharm.2012.09.034	https://doi.org/10.1016/j.ijpharm.2012.09.034	NOUN
admet-1437	591	5	https://doi.org/10.1016/j.ijpharm.2012.09.034	https://doi.org/10.1016/j.ijpharm.2012.09.034	X
admet-1437	591	6	https://doi.org/10.3390/pharmaceutics8020017	https://doi.org/10.3390/pharmaceutics8020017	PROPN
admet-1437	591	7	https://doi.org/10.3390/pharmaceutics8020017	https://doi.org/10.3390/pharmaceutics8020017	NOUN
admet-1437	591	8	https://doi.org/10.1016/j.drudis.2018.01.016	https://doi.org/10.1016/j.drudis.2018.01.016	PROPN
admet-1437	591	9	https://doi.org/10.1016/j.ijpharm.2017.12.005	https://doi.org/10.1016/j.ijpharm.2017.12.005	VERB
admet-1437	591	10	https://doi.org/10.1016/j.ijpharm.2017.12.005	https://doi.org/10.1016/j.ijpharm.2017.12.005	ADJ
admet-1437	591	11	https://doi.org/10.3109/03639045.2011.637051	https://doi.org/10.3109/03639045.2011.637051	PROPN
admet-1437	591	12	https://doi.org/10.3109/03639045.2011.637051	https://doi.org/10.3109/03639045.2011.637051	PROPN
admet-1437	591	13	https://doi.org/10.1016/j.ces.2015.03.020	https://doi.org/10.1016/j.ces.2015.03.020	PROPN
admet-1437	591	14	admet	admet	PROPN
admet-1437	591	15	&	&	CCONJ
admet-1437	591	16	dmpk	dmpk	PROPN
admet-1437	591	17	10(4	10(4	NUM
admet-1437	591	18	)	)	PUNCT
admet-1437	591	19	(	(	PUNCT
admet-1437	591	20	2022	2022	NUM
admet-1437	591	21	)	)	PUNCT
admet-1437	591	22	253	253	NUM
admet-1437	591	23	-	-	SYM
admet-1437	591	24	287	287	NUM
admet-1437	591	25	modeling	modeling	NOUN
admet-1437	591	26	of	of	ADP
admet-1437	591	27	drug	drug	NOUN
admet-1437	591	28	nanocrystals	nanocrystal	NOUN
admet-1437	591	29	dissolution	dissolution	NOUN
admet-1437	591	30	doi	doi	PROPN
admet-1437	591	31	:	:	PUNCT
admet-1437	591	32	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	591	33	283	283	NUM
admet-1437	591	34	predicting	predict	VERB
admet-1437	591	35	plasma	plasma	NOUN
admet-1437	591	36	profiles	profile	NOUN
admet-1437	591	37	.	.	PUNCT
admet-1437	592	1	european	european	ADJ
admet-1437	592	2	journal	journal	PROPN
admet-1437	592	3	of	of	ADP
admet-1437	592	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	592	5	and	and	CCONJ
admet-1437	592	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1437	592	7	77	77	NUM
admet-1437	592	8	(	(	PUNCT
admet-1437	592	9	2011	2011	NUM
admet-1437	592	10	)	)	PUNCT
admet-1437	592	11	257264	257264	NUM
admet-1437	592	12	.	.	PUNCT
admet-1437	593	1	https://doi.org/10.1016/j.ejpb.2010.10.012	https://doi.org/10.1016/j.ejpb.2010.10.012	NOUN
admet-1437	593	2	.	.	PUNCT
admet-1437	594	1	[	[	X
admet-1437	594	2	23	23	NUM
admet-1437	594	3	]	]	X
admet-1437	594	4	b.	b.	PROPN
admet-1437	594	5	hens	hens	PROPN
admet-1437	594	6	,	,	PUNCT
admet-1437	594	7	j.	j.	PROPN
admet-1437	594	8	brouwers	brouwers	PROPN
admet-1437	594	9	,	,	PUNCT
admet-1437	594	10	m.	m.	NOUN
admet-1437	594	11	corsetti	corsetti	PROPN
admet-1437	594	12	,	,	PUNCT
admet-1437	594	13	p.	p.	NOUN
admet-1437	594	14	augustijns	augustijns	NOUN
admet-1437	594	15	.	.	PUNCT
admet-1437	595	1	gastrointestinal	gastrointestinal	ADJ
admet-1437	595	2	behavior	behavior	NOUN
admet-1437	595	3	of	of	ADP
admet-1437	595	4	nanoand	nanoand	PROPN
admet-1437	595	5	microsized	microsize	VERB
admet-1437	595	6	fenofibrate	fenofibrate	NOUN
admet-1437	595	7	:	:	PUNCT
admet-1437	595	8	in	in	ADP
admet-1437	595	9	vivo	vivo	ADJ
admet-1437	595	10	evaluation	evaluation	NOUN
admet-1437	595	11	in	in	ADP
admet-1437	595	12	man	man	NOUN
admet-1437	595	13	and	and	CCONJ
admet-1437	595	14	in	in	ADP
admet-1437	595	15	vitro	vitro	X
admet-1437	595	16	simulation	simulation	NOUN
admet-1437	595	17	by	by	ADP
admet-1437	595	18	assessment	assessment	NOUN
admet-1437	595	19	of	of	ADP
admet-1437	595	20	the	the	DET
admet-1437	595	21	permeation	permeation	NOUN
admet-1437	595	22	potential	potential	NOUN
admet-1437	595	23	.	.	PUNCT
admet-1437	596	1	european	european	ADJ
admet-1437	596	2	journal	journal	PROPN
admet-1437	596	3	of	of	ADP
admet-1437	596	4	pharmaceutical	pharmaceutical	PROPN
admet-1437	596	5	sciences	science	NOUN
admet-1437	596	6	77	77	NUM
admet-1437	596	7	(	(	PUNCT
admet-1437	596	8	2015	2015	NUM
admet-1437	596	9	)	)	PUNCT
admet-1437	596	10	40	40	NUM
admet-1437	596	11	-	-	SYM
admet-1437	596	12	47	47	NUM
admet-1437	596	13	.	.	PUNCT
admet-1437	597	1	https://doi.org/10.1016/j.ejps.2015.05.023	https://doi.org/10.1016/j.ejps.2015.05.023	NOUN
admet-1437	597	2	.	.	PUNCT
admet-1437	598	1	[	[	X
admet-1437	598	2	24	24	NUM
admet-1437	598	3	]	]	X
admet-1437	598	4	c.	c.	NOUN
admet-1437	598	5	roos	roos	PROPN
admet-1437	598	6	,	,	PUNCT
admet-1437	598	7	d.	d.	PROPN
admet-1437	598	8	dahlgren	dahlgren	PROPN
admet-1437	598	9	,	,	PUNCT
admet-1437	598	10	s.	s.	PROPN
admet-1437	598	11	berg	berg	PROPN
admet-1437	598	12	,	,	PUNCT
admet-1437	598	13	j.	j.	PROPN
admet-1437	598	14	westergren	westergren	PROPN
admet-1437	598	15	,	,	PUNCT
admet-1437	598	16	b.	b.	PROPN
admet-1437	598	17	abrahamsson	abrahamsson	PROPN
admet-1437	598	18	,	,	PUNCT
admet-1437	598	19	c.	c.	PROPN
admet-1437	598	20	tannergren	tannergren	PROPN
admet-1437	598	21	,	,	PUNCT
admet-1437	598	22	e.	e.	PROPN
admet-1437	598	23	sjögren	sjögren	PROPN
admet-1437	598	24	,	,	PUNCT
admet-1437	598	25	h.	h.	PROPN
admet-1437	598	26	lennernäs	lennernäs	PROPN
admet-1437	598	27	.	.	PUNCT
admet-1437	599	1	in	in	ADP
admet-1437	599	2	vivo	vivo	ADJ
admet-1437	599	3	mechanisms	mechanism	NOUN
admet-1437	599	4	of	of	ADP
admet-1437	599	5	intestinal	intestinal	ADJ
admet-1437	599	6	drug	drug	NOUN
admet-1437	599	7	absorption	absorption	NOUN
admet-1437	599	8	from	from	ADP
admet-1437	599	9	aprepitant	aprepitant	ADJ
admet-1437	599	10	nanoformulations	nanoformulation	NOUN
admet-1437	599	11	.	.	PUNCT
admet-1437	600	1	molecular	molecular	ADJ
admet-1437	600	2	pharmaceutics	pharmaceutic	NOUN
admet-1437	600	3	14	14	NUM
admet-1437	600	4	(	(	PUNCT
admet-1437	600	5	2017	2017	NUM
admet-1437	600	6	)	)	PUNCT
admet-1437	600	7	4233	4233	NUM
admet-1437	600	8	-	-	SYM
admet-1437	600	9	4242	4242	NUM
admet-1437	600	10	.	.	PUNCT
admet-1437	601	1	https://doi.org/10.1021/-acs.molpharmaceut.7b00294	https://doi.org/10.1021/-acs.molpharmaceut.7b00294	NOUN
admet-1437	601	2	.	.	PUNCT
admet-1437	602	1	[	[	X
admet-1437	602	2	25	25	NUM
admet-1437	602	3	]	]	X
admet-1437	602	4	c.	c.	PROPN
admet-1437	602	5	roos	roos	PROPN
admet-1437	602	6	,	,	PUNCT
admet-1437	602	7	j.	j.	PROPN
admet-1437	602	8	westergren	westergren	PROPN
admet-1437	602	9	,	,	PUNCT
admet-1437	602	10	d.	d.	PROPN
admet-1437	602	11	dahlgren	dahlgren	PROPN
admet-1437	602	12	,	,	PUNCT
admet-1437	602	13	h.	h.	PROPN
admet-1437	602	14	lennernäs	lennernäs	PROPN
admet-1437	602	15	,	,	PUNCT
admet-1437	602	16	e.	e.	PROPN
admet-1437	602	17	sjögren	sjögren	PROPN
admet-1437	602	18	.	.	PUNCT
admet-1437	603	1	mechanistic	mechanistic	ADJ
admet-1437	603	2	modelling	modelling	NOUN
admet-1437	603	3	of	of	ADP
admet-1437	603	4	intestinal	intestinal	ADJ
admet-1437	603	5	drug	drug	NOUN
admet-1437	603	6	absorption	absorption	NOUN
admet-1437	603	7	–	–	PUNCT
admet-1437	603	8	the	the	PRON
admet-1437	603	9	in	in	ADP
admet-1437	603	10	vivo	vivo	ADJ
admet-1437	603	11	effects	effect	NOUN
admet-1437	603	12	of	of	ADP
admet-1437	603	13	nanoparticles	nanoparticle	NOUN
admet-1437	603	14	,	,	PUNCT
admet-1437	603	15	hydrodynamics	hydrodynamic	NOUN
admet-1437	603	16	,	,	PUNCT
admet-1437	603	17	and	and	CCONJ
admet-1437	603	18	colloidal	colloidal	NOUN
admet-1437	603	19	structures	structure	NOUN
admet-1437	603	20	.	.	PUNCT
admet-1437	604	1	european	european	ADJ
admet-1437	604	2	journal	journal	PROPN
admet-1437	604	3	of	of	ADP
admet-1437	604	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	604	5	and	and	CCONJ
admet-1437	604	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1437	604	7	133	133	NUM
admet-1437	604	8	(	(	PUNCT
admet-1437	604	9	2018	2018	NUM
admet-1437	604	10	)	)	PUNCT
admet-1437	604	11	70	70	NUM
admet-1437	604	12	-	-	SYM
admet-1437	604	13	76	76	NUM
admet-1437	604	14	.	.	PUNCT
admet-1437	605	1	https://doi.org/10.1016/j.ejpb.2018.10.006	https://doi.org/10.1016/j.ejpb.2018.10.006	ADJ
admet-1437	605	2	.	.	PUNCT
admet-1437	606	1	[	[	X
admet-1437	606	2	26	26	NUM
admet-1437	606	3	]	]	X
admet-1437	606	4	c.	c.	PROPN
admet-1437	606	5	litou	litou	PROPN
admet-1437	606	6	,	,	PUNCT
admet-1437	606	7	n.	n.	PROPN
admet-1437	606	8	patel	patel	PROPN
admet-1437	606	9	,	,	PUNCT
admet-1437	606	10	d.b	d.b	PROPN
admet-1437	606	11	.	.	PROPN
admet-1437	606	12	turner	turner	PROPN
admet-1437	606	13	,	,	PUNCT
admet-1437	606	14	e.	e.	PROPN
admet-1437	606	15	kostewicza	kostewicza	PROPN
admet-1437	606	16	,	,	PUNCT
admet-1437	606	17	m.	m.	PROPN
admet-1437	606	18	kuentz	kuentz	PROPN
admet-1437	606	19	,	,	PUNCT
admet-1437	606	20	k.j	k.j	PROPN
admet-1437	606	21	.	.	PROPN
admet-1437	606	22	box	box	PROPN
admet-1437	606	23	,	,	PUNCT
admet-1437	606	24	j.	j.	PROPN
admet-1437	606	25	dressman	dressman	PROPN
admet-1437	606	26	.	.	PUNCT
admet-1437	607	1	combining	combine	VERB
admet-1437	607	2	biorelevant	biorelevant	NOUN
admet-1437	607	3	in	in	ADP
admet-1437	607	4	vitro	vitro	X
admet-1437	607	5	and	and	CCONJ
admet-1437	607	6	in	in	ADP
admet-1437	607	7	silico	silico	NOUN
admet-1437	607	8	tools	tool	NOUN
admet-1437	607	9	to	to	PART
admet-1437	607	10	simulate	simulate	VERB
admet-1437	607	11	and	and	CCONJ
admet-1437	607	12	better	well	ADV
admet-1437	607	13	understand	understand	VERB
admet-1437	607	14	the	the	DET
admet-1437	607	15	in	in	ADP
admet-1437	607	16	vivo	vivo	ADJ
admet-1437	607	17	performance	performance	NOUN
admet-1437	607	18	of	of	ADP
admet-1437	607	19	a	a	DET
admet-1437	607	20	nano	nano	NOUN
admet-1437	607	21	-	-	PUNCT
admet-1437	607	22	sized	sized	ADJ
admet-1437	607	23	formulation	formulation	NOUN
admet-1437	607	24	of	of	ADP
admet-1437	607	25	aprepitant	aprepitant	ADJ
admet-1437	607	26	in	in	ADP
admet-1437	607	27	the	the	DET
admet-1437	607	28	fasted	fast	VERB
admet-1437	607	29	and	and	CCONJ
admet-1437	607	30	fed	fed	PROPN
admet-1437	607	31	states	state	NOUN
admet-1437	607	32	.	.	PUNCT
admet-1437	608	1	european	european	ADJ
admet-1437	608	2	journal	journal	PROPN
admet-1437	608	3	of	of	ADP
admet-1437	608	4	pharmaceutical	pharmaceutical	PROPN
admet-1437	608	5	sciences	science	NOUN
admet-1437	608	6	138	138	NUM
admet-1437	608	7	(	(	PUNCT
admet-1437	608	8	2019	2019	NUM
admet-1437	608	9	)	)	PUNCT
admet-1437	608	10	105031	105031	NUM
admet-1437	608	11	.	.	PUNCT
admet-1437	609	1	https://doi.org/10.1016/j.ejps.2019.105031	https://doi.org/10.1016/j.ejps.2019.105031	NOUN
admet-1437	609	2	.	.	PUNCT
admet-1437	610	1	[	[	X
admet-1437	610	2	27	27	NUM
admet-1437	610	3	]	]	PUNCT
admet-1437	610	4	m.	m.	NOUN
admet-1437	610	5	imono	imono	PROPN
admet-1437	610	6	,	,	PUNCT
admet-1437	610	7	h.	h.	PROPN
admet-1437	610	8	uchiyama	uchiyama	PROPN
admet-1437	610	9	,	,	PUNCT
admet-1437	610	10	s.	s.	PROPN
admet-1437	610	11	yoshida	yoshida	PROPN
admet-1437	610	12	,	,	PUNCT
admet-1437	610	13	s.	s.	PROPN
admet-1437	610	14	miyazaki	miyazaki	PROPN
admet-1437	610	15	,	,	PUNCT
admet-1437	610	16	n.	n.	PROPN
admet-1437	610	17	tamura	tamura	PROPN
admet-1437	610	18	,	,	PUNCT
admet-1437	610	19	h.	h.	PROPN
admet-1437	610	20	tsutsumimoto	tsutsumimoto	PROPN
admet-1437	610	21	,	,	PUNCT
admet-1437	610	22	k.	k.	PROPN
admet-1437	610	23	kadota	kadota	PROPN
admet-1437	610	24	,	,	PUNCT
admet-1437	610	25	y.	y.	PROPN
admet-1437	610	26	tozuka	tozuka	PROPN
admet-1437	610	27	.	.	PUNCT
admet-1437	611	1	the	the	DET
admet-1437	611	2	elucidation	elucidation	NOUN
admet-1437	611	3	of	of	ADP
admet-1437	611	4	key	key	ADJ
admet-1437	611	5	factors	factor	NOUN
admet-1437	611	6	for	for	ADP
admet-1437	611	7	oral	oral	ADJ
admet-1437	611	8	absorption	absorption	NOUN
admet-1437	611	9	enhancement	enhancement	NOUN
admet-1437	611	10	of	of	ADP
admet-1437	611	11	nanocrystal	nanocrystal	ADJ
admet-1437	611	12	formulations	formulation	NOUN
admet-1437	611	13	:	:	PUNCT
admet-1437	611	14	in	in	ADP
admet-1437	611	15	vitro	vitro	X
admet-1437	611	16	–	–	PUNCT
admet-1437	611	17	in	in	ADP
admet-1437	611	18	vivo	vivo	ADJ
admet-1437	611	19	correlation	correlation	NOUN
admet-1437	611	20	of	of	ADP
admet-1437	611	21	nanocrystals	nanocrystal	NOUN
admet-1437	611	22	.	.	PUNCT
admet-1437	612	1	european	european	ADJ
admet-1437	612	2	journal	journal	PROPN
admet-1437	612	3	of	of	ADP
admet-1437	612	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	612	5	and	and	CCONJ
admet-1437	612	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1437	612	7	146	146	NUM
admet-1437	612	8	(	(	PUNCT
admet-1437	612	9	2020	2020	NUM
admet-1437	612	10	)	)	PUNCT
admet-1437	612	11	84	84	NUM
admet-1437	612	12	-	-	SYM
admet-1437	612	13	92	92	NUM
admet-1437	612	14	.	.	PUNCT
admet-1437	613	1	https://doi.org/10.1016/j.ejpb.2019.12.002	https://doi.org/10.1016/j.ejpb.2019.12.002	NOUN
admet-1437	613	2	.	.	PUNCT
admet-1437	614	1	[	[	X
admet-1437	614	2	28	28	NUM
admet-1437	614	3	]	]	X
admet-1437	614	4	m.	m.	NOUN
admet-1437	614	5	guo	guo	PROPN
admet-1437	614	6	,	,	PUNCT
admet-1437	614	7	m.	m.	PROPN
admet-1437	614	8	wei	wei	PROPN
admet-1437	614	9	,	,	PUNCT
admet-1437	614	10	w.	w.	PROPN
admet-1437	614	11	li	li	PROPN
admet-1437	614	12	,	,	PUNCT
admet-1437	614	13	m.	m.	PROPN
admet-1437	614	14	guo	guo	PROPN
admet-1437	614	15	,	,	PUNCT
admet-1437	614	16	c.	c.	PROPN
admet-1437	614	17	guo	guo	PROPN
admet-1437	614	18	.	.	PROPN
admet-1437	614	19	,	,	PUNCT
admet-1437	614	20	m.	m.	PROPN
admet-1437	614	21	ma	ma	PROPN
admet-1437	614	22	,	,	PUNCT
admet-1437	614	23	y.	y.	PROPN
admet-1437	614	24	wang	wang	PROPN
admet-1437	614	25	,	,	PUNCT
admet-1437	614	26	z.	z.	PROPN
admet-1437	614	27	yang	yang	PROPN
admet-1437	614	28	,	,	PUNCT
admet-1437	614	29	m.	m.	PROPN
admet-1437	614	30	li	li	PROPN
admet-1437	614	31	,	,	PUNCT
admet-1437	614	32	q.	q.	PROPN
admet-1437	614	33	fu	fu	PROPN
admet-1437	614	34	,	,	PUNCT
admet-1437	614	35	l.	l.	PROPN
admet-1437	614	36	yang	yang	PROPN
admet-1437	614	37	,	,	PUNCT
admet-1437	614	38	z.	z.	PROPN
admet-1437	614	39	he	he	PRON
admet-1437	614	40	.	.	PUNCT
admet-1437	615	1	impacts	impact	NOUN
admet-1437	615	2	of	of	ADP
admet-1437	615	3	particle	particle	NOUN
admet-1437	615	4	shapes	shape	NOUN
admet-1437	615	5	on	on	ADP
admet-1437	615	6	the	the	DET
admet-1437	615	7	oral	oral	ADJ
admet-1437	615	8	delivery	delivery	NOUN
admet-1437	615	9	of	of	ADP
admet-1437	615	10	drug	drug	NOUN
admet-1437	615	11	nanocrystals	nanocrystal	NOUN
admet-1437	615	12	:	:	PUNCT
admet-1437	615	13	mucus	mucus	NOUN
admet-1437	615	14	permeation	permeation	NOUN
admet-1437	615	15	,	,	PUNCT
admet-1437	615	16	transepithelial	transepithelial	ADJ
admet-1437	615	17	transport	transport	NOUN
admet-1437	615	18	and	and	CCONJ
admet-1437	615	19	bioavailability	bioavailability	NOUN
admet-1437	615	20	.	.	PUNCT
admet-1437	616	1	journal	journal	PROPN
admet-1437	616	2	of	of	ADP
admet-1437	616	3	controlled	control	VERB
admet-1437	616	4	release	release	NOUN
admet-1437	616	5	307	307	NUM
admet-1437	616	6	(	(	PUNCT
admet-1437	616	7	2019	2019	NUM
admet-1437	616	8	)	)	PUNCT
admet-1437	616	9	64	64	NUM
admet-1437	616	10	-	-	SYM
admet-1437	616	11	75	75	NUM
admet-1437	616	12	.	.	PUNCT
admet-1437	617	1	https://doi.org/10.1016/j.jconrel.2019.06.015	https://doi.org/10.1016/j.jconrel.2019.06.015	VERB
admet-1437	617	2	.	.	PUNCT
admet-1437	618	1	[	[	X
admet-1437	618	2	29	29	NUM
admet-1437	618	3	]	]	X
admet-1437	618	4	b.	b.	PROPN
admet-1437	618	5	abrahamsson	abrahamsson	PROPN
admet-1437	618	6	,	,	PUNCT
admet-1437	618	7	m.	m.	NOUN
admet-1437	618	8	mcallister	mcallister	PROPN
admet-1437	618	9	,	,	PUNCT
admet-1437	618	10	p.	p.	NOUN
admet-1437	618	11	augustijns	augustijns	NOUN
admet-1437	618	12	,	,	PUNCT
admet-1437	618	13	p.	p.	PROPN
admet-1437	618	14	zane	zane	PROPN
admet-1437	618	15	,	,	PUNCT
admet-1437	618	16	j.	j.	PROPN
admet-1437	618	17	butler	butler	PROPN
admet-1437	618	18	,	,	PUNCT
admet-1437	618	19	r.	r.	PROPN
admet-1437	618	20	holm	holm	PROPN
admet-1437	618	21	,	,	PUNCT
admet-1437	618	22	p.	p.	PROPN
admet-1437	618	23	langguth	langguth	PROPN
admet-1437	618	24	,	,	PUNCT
admet-1437	618	25	a.	a.	PROPN
admet-1437	618	26	lindahl	lindahl	PROPN
admet-1437	618	27	,	,	PUNCT
admet-1437	618	28	a.	a.	NOUN
admet-1437	618	29	müllertz	müllertz	PROPN
admet-1437	618	30	,	,	PUNCT
admet-1437	618	31	x.	x.	PROPN
admet-1437	618	32	pepin	pepin	PROPN
admet-1437	618	33	,	,	PUNCT
admet-1437	618	34	a.	a.	PROPN
admet-1437	618	35	rostami	rostami	PROPN
admet-1437	618	36	-	-	PUNCT
admet-1437	618	37	hodjegan	hodjegan	PROPN
admet-1437	618	38	,	,	PUNCT
admet-1437	618	39	e.	e.	PROPN
admet-1437	618	40	sjögren	sjögren	PROPN
admet-1437	618	41	,	,	PUNCT
admet-1437	618	42	m.	m.	NOUN
admet-1437	618	43	berntsson	berntsson	PROPN
admet-1437	618	44	,	,	PUNCT
admet-1437	618	45	h.	h.	PROPN
admet-1437	618	46	lennernäs	lennernäs	PROPN
admet-1437	618	47	.	.	PUNCT
admet-1437	619	1	six	six	NUM
admet-1437	619	2	years	year	NOUN
admet-1437	619	3	of	of	ADP
admet-1437	619	4	progress	progress	NOUN
admet-1437	619	5	in	in	ADP
admet-1437	619	6	the	the	DET
admet-1437	619	7	oral	oral	ADJ
admet-1437	619	8	biopharmaceutics	biopharmaceutics	NOUN
admet-1437	619	9	area	area	NOUN
admet-1437	619	10	–	–	PUNCT
admet-1437	619	11	a	a	DET
admet-1437	619	12	summary	summary	NOUN
admet-1437	619	13	from	from	ADP
admet-1437	619	14	the	the	DET
admet-1437	619	15	imi	imi	PROPN
admet-1437	619	16	orbito	orbito	PROPN
admet-1437	619	17	project	project	PROPN
admet-1437	619	18	.	.	PUNCT
admet-1437	620	1	european	european	PROPN
admet-1437	620	2	journal	journal	PROPN
admet-1437	620	3	of	of	ADP
admet-1437	620	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	620	5	and	and	CCONJ
admet-1437	620	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1437	620	7	152	152	NUM
admet-1437	620	8	(	(	PUNCT
admet-1437	620	9	2020	2020	NUM
admet-1437	620	10	)	)	PUNCT
admet-1437	620	11	236	236	NUM
admet-1437	620	12	-	-	SYM
admet-1437	620	13	247	247	NUM
admet-1437	620	14	.	.	PUNCT
admet-1437	621	1	https://doi.org/10.1016/j.ejpb.2020.05.008	https://doi.org/10.1016/j.ejpb.2020.05.008	NOUN
admet-1437	621	2	.	.	PUNCT
admet-1437	622	1	[	[	X
admet-1437	622	2	30	30	NUM
admet-1437	622	3	]	]	X
admet-1437	622	4	h.	h.	NOUN
admet-1437	622	5	palmelund	palmelund	PROPN
admet-1437	622	6	,	,	PUNCT
admet-1437	622	7	j.b	j.b	PROPN
admet-1437	622	8	.	.	PROPN
admet-1437	622	9	eriksen	eriksen	PROPN
admet-1437	622	10	,	,	PUNCT
admet-1437	622	11	a.	a.	PROPN
admet-1437	622	12	bauer	bauer	PROPN
admet-1437	622	13	-	-	PUNCT
admet-1437	622	14	brandl	brandl	PROPN
admet-1437	622	15	,	,	PUNCT
admet-1437	622	16	j.	j.	PROPN
admet-1437	622	17	rantanen	rantanen	PROPN
admet-1437	622	18	,	,	PUNCT
admet-1437	622	19	k.	k.	PROPN
admet-1437	622	20	löbmann	löbmann	PROPN
admet-1437	622	21	.	.	PUNCT
admet-1437	623	1	enabling	enable	VERB
admet-1437	623	2	formulations	formulation	NOUN
admet-1437	623	3	of	of	ADP
admet-1437	623	4	aprepitant	aprepitant	ADJ
admet-1437	623	5	:	:	PUNCT
admet-1437	623	6	in	in	ADP
admet-1437	623	7	vitro	vitro	X
admet-1437	623	8	and	and	CCONJ
admet-1437	623	9	in	in	ADP
admet-1437	623	10	vivo	vivo	ADJ
admet-1437	623	11	comparison	comparison	NOUN
admet-1437	623	12	of	of	ADP
admet-1437	623	13	nanocrystalline	nanocrystalline	NOUN
admet-1437	623	14	,	,	PUNCT
admet-1437	623	15	amorphous	amorphous	ADJ
admet-1437	623	16	and	and	CCONJ
admet-1437	623	17	deep	deep	ADJ
admet-1437	623	18	eutectic	eutectic	ADJ
admet-1437	623	19	solvent	solvent	NOUN
admet-1437	623	20	based	base	VERB
admet-1437	623	21	formulations	formulation	NOUN
admet-1437	623	22	.	.	PUNCT
admet-1437	624	1	international	international	ADJ
admet-1437	624	2	journal	journal	PROPN
admet-1437	624	3	of	of	ADP
admet-1437	624	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	624	5	:	:	PUNCT
admet-1437	624	6	x	x	SYM
admet-1437	624	7	3	3	NUM
admet-1437	624	8	(	(	PUNCT
admet-1437	624	9	2021	2021	NUM
admet-1437	624	10	)	)	PUNCT
admet-1437	624	11	100083	100083	NUM
admet-1437	624	12	.	.	PUNCT
admet-1437	625	1	https://doi.org/10.1016/j.ijpx.2021.100083	https://doi.org/10.1016/j.ijpx.2021.100083	NOUN
admet-1437	625	2	.	.	PUNCT
admet-1437	626	1	[	[	X
admet-1437	626	2	31	31	NUM
admet-1437	626	3	]	]	PUNCT
admet-1437	626	4	p.	p.	PROPN
admet-1437	626	5	liu	liu	PROPN
admet-1437	626	6	,	,	PUNCT
admet-1437	626	7	o.	o.	PROPN
admet-1437	626	8	de	de	PROPN
admet-1437	626	9	wulf	wulf	PROPN
admet-1437	626	10	,	,	PUNCT
admet-1437	626	11	j.	j.	PROPN
admet-1437	626	12	laru	laru	PROPN
admet-1437	626	13	,	,	PUNCT
admet-1437	626	14	t.	t.	PROPN
admet-1437	626	15	heikkilä	heikkilä	PROPN
admet-1437	626	16	,	,	PUNCT
admet-1437	626	17	b.	b.	PROPN
admet-1437	626	18	van	van	PROPN
admet-1437	626	19	veen	veen	PROPN
admet-1437	626	20	,	,	PUNCT
admet-1437	626	21	j.	j.	PROPN
admet-1437	626	22	kiesvaara	kiesvaara	PROPN
admet-1437	626	23	,	,	PUNCT
admet-1437	626	24	j.	j.	PROPN
admet-1437	626	25	hirvonen	hirvonen	PROPN
admet-1437	626	26	,	,	PUNCT
admet-1437	626	27	l.	l.	PROPN
admet-1437	626	28	peltonen	peltonen	PROPN
admet-1437	626	29	,	,	PUNCT
admet-1437	626	30	t.	t.	PROPN
admet-1437	626	31	laaksonen	laaksonen	PROPN
admet-1437	626	32	.	.	PUNCT
admet-1437	627	1	dissolution	dissolution	PROPN
admet-1437	627	2	studies	study	NOUN
admet-1437	627	3	of	of	ADP
admet-1437	627	4	poorly	poorly	ADV
admet-1437	627	5	soluble	soluble	ADJ
admet-1437	627	6	drug	drug	NOUN
admet-1437	627	7	nanosuspensions	nanosuspension	NOUN
admet-1437	627	8	in	in	ADP
admet-1437	627	9	non	non	ADJ
admet-1437	627	10	-	-	ADJ
admet-1437	627	11	sink	sink	ADJ
admet-1437	627	12	conditions	condition	NOUN
admet-1437	627	13	.	.	PUNCT
admet-1437	628	1	aaps	aap	NOUN
admet-1437	628	2	pharmscitech	pharmscitech	VERB
admet-1437	628	3	14	14	NUM
admet-1437	628	4	(	(	PUNCT
admet-1437	628	5	2013	2013	NUM
admet-1437	628	6	)	)	PUNCT
admet-1437	628	7	748	748	NUM
admet-1437	628	8	-	-	SYM
admet-1437	628	9	756	756	NUM
admet-1437	628	10	.	.	PUNCT
admet-1437	629	1	https://doi.org/10.1208/s12249-013-9960-2	https://doi.org/10.1208/s12249-013-9960-2	PROPN
admet-1437	629	2	.	.	PUNCT
admet-1437	630	1	[	[	X
admet-1437	630	2	32	32	NUM
admet-1437	630	3	]	]	PUNCT
admet-1437	630	4	v.	v.	ADP
admet-1437	630	5	braig	braig	PROPN
admet-1437	630	6	,	,	PUNCT
admet-1437	630	7	c.	c.	PROPN
admet-1437	630	8	konnerth	konnerth	PROPN
admet-1437	630	9	,	,	PUNCT
admet-1437	630	10	w	w	NOUN
admet-1437	630	11	peukert	peukert	NOUN
admet-1437	630	12	,	,	PUNCT
admet-1437	630	13	g.	g.	PROPN
admet-1437	630	14	lee	lee	PROPN
admet-1437	630	15	.	.	PROPN
admet-1437	630	16	enhanced	enhance	VERB
admet-1437	630	17	dissolution	dissolution	NOUN
admet-1437	630	18	of	of	ADP
admet-1437	630	19	naproxen	naproxen	NOUN
admet-1437	630	20	from	from	ADP
admet-1437	630	21	pure	pure	ADJ
admet-1437	630	22	-	-	PUNCT
admet-1437	630	23	drug	drug	NOUN
admet-1437	630	24	,	,	PUNCT
admet-1437	630	25	crystalline	crystalline	NOUN
admet-1437	630	26	nanoparticles	nanoparticle	NOUN
admet-1437	630	27	:	:	PUNCT
admet-1437	630	28	a	a	DET
admet-1437	630	29	case	case	NOUN
admet-1437	630	30	study	study	NOUN
admet-1437	630	31	formulated	formulate	VERB
admet-1437	630	32	into	into	ADP
admet-1437	630	33	spray	spray	NOUN
admet-1437	630	34	-	-	PUNCT
admet-1437	630	35	dried	dry	VERB
admet-1437	630	36	granules	granule	NOUN
admet-1437	630	37	and	and	CCONJ
admet-1437	630	38	compressed	compress	VERB
admet-1437	630	39	tablets	tablet	NOUN
admet-1437	630	40	.	.	PUNCT
admet-1437	631	1	international	international	ADJ
admet-1437	631	2	journal	journal	PROPN
admet-1437	631	3	of	of	ADP
admet-1437	631	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	631	5	554	554	NUM
admet-1437	631	6	(	(	PUNCT
admet-1437	631	7	2019	2019	NUM
admet-1437	631	8	)	)	PUNCT
admet-1437	631	9	54	54	NUM
admet-1437	631	10	-	-	SYM
admet-1437	631	11	60	60	NUM
admet-1437	631	12	.	.	PUNCT
admet-1437	632	1	https://doi.org/10.1016/j.ijpharm.2018.09.069	https://doi.org/10.1016/j.ijpharm.2018.09.069	NOUN
admet-1437	632	2	.	.	PUNCT
admet-1437	633	1	[	[	X
admet-1437	633	2	33	33	NUM
admet-1437	633	3	]	]	X
admet-1437	633	4	d.	d.	PROPN
admet-1437	633	5	sironi	sironi	PROPN
admet-1437	633	6	,	,	PUNCT
admet-1437	633	7	j.	j.	PROPN
admet-1437	633	8	rosenberg	rosenberg	PROPN
admet-1437	633	9	,	,	PUNCT
admet-1437	633	10	a.	a.	PROPN
admet-1437	633	11	bauer	bauer	PROPN
admet-1437	633	12	-	-	PUNCT
admet-1437	633	13	brandl	brandl	PROPN
admet-1437	633	14	,	,	PUNCT
admet-1437	633	15	m.	m.	NOUN
admet-1437	633	16	brandl	brandl	PROPN
admet-1437	633	17	.	.	PUNCT
admet-1437	634	1	dynamic	dynamic	ADJ
admet-1437	634	2	dissolution-/permeation	dissolution-/permeation	NOUN
admet-1437	634	3	-	-	PUNCT
admet-1437	634	4	testing	testing	NOUN
admet-1437	634	5	of	of	ADP
admet-1437	634	6	nano	nano	NOUN
admet-1437	634	7	and	and	CCONJ
admet-1437	634	8	microparticle	microparticle	NOUN
admet-1437	634	9	formulations	formulation	NOUN
admet-1437	634	10	of	of	ADP
admet-1437	634	11	fenofibrate	fenofibrate	NOUN
admet-1437	634	12	.	.	PUNCT
admet-1437	635	1	european	european	PROPN
admet-1437	635	2	journal	journal	PROPN
admet-1437	635	3	of	of	ADP
admet-1437	635	4	pharmaceutical	pharmaceutical	PROPN
admet-1437	635	5	sciences	science	NOUN
admet-1437	635	6	96	96	NUM
admet-1437	635	7	(	(	PUNCT
admet-1437	635	8	2017	2017	NUM
admet-1437	635	9	)	)	PUNCT
admet-1437	635	10	20	20	NUM
admet-1437	635	11	-	-	SYM
admet-1437	635	12	27	27	NUM
admet-1437	635	13	.	.	PUNCT
admet-1437	636	1	https://doi.org/10.1016/j.ejps.2016.09.001	https://doi.org/10.1016/j.ejps.2016.09.001	NOUN
admet-1437	636	2	.	.	PUNCT
admet-1437	637	1	[	[	X
admet-1437	637	2	34	34	NUM
admet-1437	637	3	]	]	PUNCT
admet-1437	637	4	k.	k.	PROPN
admet-1437	637	5	tsinman	tsinman	PROPN
admet-1437	637	6	,	,	PUNCT
admet-1437	637	7	o.	o.	PROPN
admet-1437	637	8	tsinman	tsinman	PROPN
admet-1437	637	9	,	,	PUNCT
admet-1437	637	10	r.	r.	PROPN
admet-1437	637	11	lingamaneni	lingamaneni	PROPN
admet-1437	637	12	,	,	PUNCT
admet-1437	637	13	s.	s.	PROPN
admet-1437	637	14	zhu	zhu	PROPN
admet-1437	637	15	,	,	PUNCT
admet-1437	637	16	b.	b.	PROPN
admet-1437	637	17	riebesehl	riebesehl	PROPN
admet-1437	637	18	,	,	PUNCT
admet-1437	637	19	a.	a.	PROPN
admet-1437	637	20	grandeury	grandeury	PROPN
admet-1437	637	21	,	,	PUNCT
admet-1437	637	22	m.	m.	NOUN
admet-1437	637	23	juhnke	juhnke	PROPN
admet-1437	637	24	,	,	PUNCT
admet-1437	637	25	b.	b.	PROPN
admet-1437	637	26	van	van	PROPN
admet-1437	637	27	eerdenbrugh	eerdenbrugh	PROPN
admet-1437	637	28	.	.	PUNCT
admet-1437	638	1	ranking	rank	VERB
admet-1437	638	2	itraconazole	itraconazole	ADJ
admet-1437	638	3	formulations	formulation	NOUN
admet-1437	638	4	based	base	VERB
admet-1437	638	5	on	on	ADP
admet-1437	638	6	the	the	DET
admet-1437	638	7	flux	flux	NOUN
admet-1437	638	8	through	through	ADP
admet-1437	638	9	artificial	artificial	ADJ
admet-1437	638	10	lipophilic	lipophilic	ADJ
admet-1437	638	11	membrane	membrane	NOUN
admet-1437	638	12	.	.	PUNCT
admet-1437	639	1	pharmaceutical	pharmaceutical	ADJ
admet-1437	639	2	research	research	NOUN
admet-1437	639	3	35	35	NUM
admet-1437	639	4	(	(	PUNCT
admet-1437	639	5	2018	2018	NUM
admet-1437	639	6	)	)	PUNCT
admet-1437	639	7	161	161	NUM
admet-1437	639	8	.	.	PUNCT
admet-1437	639	9	https://doi.org/10.1007/s11095-018-2440-3	https://doi.org/10.1007/s11095-018-2440-3	NUM
admet-1437	639	10	.	.	PUNCT
admet-1437	640	1	[	[	X
admet-1437	640	2	35	35	NUM
admet-1437	640	3	]	]	PUNCT
admet-1437	640	4	j.	j.	PROPN
admet-1437	640	5	li	li	PROPN
admet-1437	640	6	,	,	PUNCT
admet-1437	640	7	l.b	l.b	PROPN
admet-1437	640	8	.	.	PROPN
admet-1437	640	9	li	li	PROPN
admet-1437	640	10	,	,	PUNCT
admet-1437	640	11	n.	n.	PROPN
admet-1437	640	12	nessah	nessah	PROPN
admet-1437	640	13	,	,	PUNCT
admet-1437	640	14	y.	y.	PROPN
admet-1437	640	15	huang	huang	PROPN
admet-1437	640	16	,	,	PUNCT
admet-1437	640	17	c.	c.	PROPN
admet-1437	640	18	hidalgo	hidalgo	PROPN
admet-1437	640	19	,	,	PUNCT
admet-1437	640	20	a.	a.	PROPN
admet-1437	640	21	owen	owen	PROPN
admet-1437	640	22	,	,	PUNCT
admet-1437	640	23	i.j	i.j	PROPN
admet-1437	640	24	.	.	PROPN
admet-1437	640	25	hidalgo	hidalgo	PROPN
admet-1437	640	26	.	.	PUNCT
admet-1437	641	1	simultaneous	simultaneous	ADJ
admet-1437	641	2	analysis	analysis	NOUN
admet-1437	641	3	of	of	ADP
admet-1437	641	4	dissolution	dissolution	NOUN
admet-1437	641	5	and	and	CCONJ
admet-1437	641	6	permeation	permeation	NOUN
admet-1437	641	7	profiles	profile	NOUN
admet-1437	641	8	of	of	ADP
admet-1437	641	9	nanosized	nanosized	ADJ
admet-1437	641	10	and	and	CCONJ
admet-1437	641	11	microsized	microsize	VERB
admet-1437	641	12	formulations	formulation	NOUN
admet-1437	641	13	of	of	ADP
admet-1437	641	14	indomethacin	indomethacin	NOUN
admet-1437	641	15	using	use	VERB
admet-1437	641	16	the	the	DET
admet-1437	641	17	in	in	ADV
admet-1437	641	18	vitro	vitro	X
admet-1437	641	19	dissolution	dissolution	NOUN
admet-1437	641	20	absorption	absorption	NOUN
admet-1437	641	21	system	system	NOUN
admet-1437	641	22	2	2	NUM
admet-1437	641	23	.	.	PUNCT
admet-1437	641	24	journal	journal	NOUN
admet-1437	641	25	of	of	ADP
admet-1437	641	26	pharmaceutical	pharmaceutical	PROPN
admet-1437	641	27	sciences	science	NOUN
admet-1437	641	28	108	108	NUM
admet-1437	641	29	(	(	PUNCT
admet-1437	641	30	2019	2019	NUM
admet-1437	641	31	)	)	PUNCT
admet-1437	641	32	2334	2334	NUM
admet-1437	641	33	-	-	SYM
admet-1437	641	34	2340	2340	NUM
admet-1437	641	35	.	.	PUNCT
admet-1437	642	1	https://doi.org/10.1016/j.xphs.2019.01.032	https://doi.org/10.1016/j.xphs.2019.01.032	NOUN
admet-1437	642	2	.	.	PUNCT
admet-1437	643	1	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	NOUN
admet-1437	643	2	https://doi.org/10.1016/j.ejpb.2010.10.012	https://doi.org/10.1016/j.ejpb.2010.10.012	NOUN
admet-1437	643	3	https://doi.org/10.1016/j.ejps.2015.05.023	https://doi.org/10.1016/j.ejps.2015.05.023	NOUN
admet-1437	643	4	https://doi.org/10.1016/j.ejps.2015.05.023	https://doi.org/10.1016/j.ejps.2015.05.023	NOUN
admet-1437	643	5	https://doi.org/10.1021/-acs.molpharmaceut.7b00294	https://doi.org/10.1021/-acs.molpharmaceut.7b00294	NOUN
admet-1437	643	6	https://doi.org/10.1016/j.ejpb.2018.10.006	https://doi.org/10.1016/j.ejpb.2018.10.006	PRON
admet-1437	643	7	https://doi.org/10.1016/j.ejpb.2018.10.006	https://doi.org/10.1016/j.ejpb.2018.10.006	PROPN
admet-1437	643	8	https://doi.org/10.1016/j.ejps.2019.105031	https://doi.org/10.1016/j.ejps.2019.105031	NOUN
admet-1437	643	9	https://doi.org/10.1016/j.ejpb.2019.12.002	https://doi.org/10.1016/j.ejpb.2019.12.002	NOUN
admet-1437	643	10	https://doi.org/10.1016/j.jconrel.2019.06.015	https://doi.org/10.1016/j.jconrel.2019.06.015	PRON
admet-1437	643	11	https://doi.org/10.1016/j.ejpb.2020.05.008	https://doi.org/10.1016/j.ejpb.2020.05.008	NOUN
admet-1437	643	12	https://doi.org/10.1016/j.ejpb.2020.05.008	https://doi.org/10.1016/j.ejpb.2020.05.008	NOUN
admet-1437	643	13	https://doi.org/10.1016/j.ijpx.2021.100083	https://doi.org/10.1016/j.ijpx.2021.100083	NOUN
admet-1437	643	14	https://doi.org/10.1016/j.ijpx.2021.100083	https://doi.org/10.1016/j.ijpx.2021.100083	PROPN
admet-1437	643	15	https://doi.org/10.1208/s12249-013-9960-2	https://doi.org/10.1208/s12249-013-9960-2	PROPN
admet-1437	643	16	https://doi.org/10.1016/j.ijpharm.2018.09.069	https://doi.org/10.1016/j.ijpharm.2018.09.069	PROPN
admet-1437	643	17	https://doi.org/10.1016/j.ijpharm.2018.09.069	https://doi.org/10.1016/j.ijpharm.2018.09.069	PROPN
admet-1437	643	18	https://doi.org/10.1016/j.ejps.2016.09.001	https://doi.org/10.1016/j.ejps.2016.09.001	NOUN
admet-1437	643	19	https://doi.org/10.1007/s11095-018-2440-3	https://doi.org/10.1007/s11095-018-2440-3	NOUN
admet-1437	644	1	https://doi.org/10.1016/j.xphs.2019.01.032	https://doi.org/10.1016/j.xphs.2019.01.032	NUM
admet-1437	644	2	bonhoeffer	bonhoeffer	PROPN
admet-1437	644	3	et	et	PROPN
admet-1437	644	4	al	al	PROPN
admet-1437	644	5	.	.	PROPN
admet-1437	644	6	admet	admet	PROPN
admet-1437	644	7	&	&	CCONJ
admet-1437	644	8	dmpk	dmpk	PROPN
admet-1437	644	9	10(4	10(4	NUM
admet-1437	644	10	)	)	PUNCT
admet-1437	644	11	(	(	PUNCT
admet-1437	644	12	2022	2022	NUM
admet-1437	644	13	)	)	PUNCT
admet-1437	644	14	253	253	NUM
admet-1437	644	15	-	-	SYM
admet-1437	644	16	287	287	NUM
admet-1437	644	17	284	284	NUM
admet-1437	645	1	[	[	X
admet-1437	645	2	36	36	NUM
admet-1437	645	3	]	]	PUNCT
admet-1437	645	4	m.	m.	NOUN
admet-1437	645	5	imono	imono	PROPN
admet-1437	645	6	,	,	PUNCT
admet-1437	645	7	h.	h.	PROPN
admet-1437	645	8	uchiyama	uchiyama	PROPN
admet-1437	645	9	,	,	PUNCT
admet-1437	645	10	h.	h.	PROPN
admet-1437	645	11	ueda	ueda	PROPN
admet-1437	645	12	,	,	PUNCT
admet-1437	645	13	k.	k.	PROPN
admet-1437	645	14	kadota	kadota	PROPN
admet-1437	645	15	,	,	PUNCT
admet-1437	645	16	y.	y.	PROPN
admet-1437	645	17	tozuka	tozuka	PROPN
admet-1437	645	18	.	.	PUNCT
admet-1437	646	1	in	in	ADP
admet-1437	646	2	-	-	PUNCT
admet-1437	646	3	situ	situ	NOUN
admet-1437	646	4	dissolution	dissolution	NOUN
admet-1437	646	5	and	and	CCONJ
admet-1437	646	6	permeation	permeation	NOUN
admet-1437	646	7	studies	study	NOUN
admet-1437	646	8	of	of	ADP
admet-1437	646	9	nanocrystal	nanocrystal	ADJ
admet-1437	646	10	formulations	formulation	NOUN
admet-1437	646	11	with	with	ADP
admet-1437	646	12	second	second	ADJ
admet-1437	646	13	-	-	PUNCT
admet-1437	646	14	derivative	derivative	ADJ
admet-1437	646	15	uv	uv	NOUN
admet-1437	646	16	spectroscopy	spectroscopy	NOUN
admet-1437	646	17	.	.	PUNCT
admet-1437	647	1	international	international	ADJ
admet-1437	647	2	journal	journal	PROPN
admet-1437	647	3	of	of	ADP
admet-1437	647	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	647	5	558	558	NUM
admet-1437	647	6	(	(	PUNCT
admet-1437	647	7	2019	2019	NUM
admet-1437	647	8	)	)	PUNCT
admet-1437	647	9	242249	242249	NUM
admet-1437	647	10	.	.	PUNCT
admet-1437	648	1	https://doi.org/10.1016/j.ijpharm.2018.12.086	https://doi.org/10.1016/j.ijpharm.2018.12.086	VERB
admet-1437	648	2	.	.	PUNCT
admet-1437	649	1	[	[	X
admet-1437	649	2	37	37	NUM
admet-1437	649	3	]	]	X
admet-1437	649	4	f.a	f.a	PROPN
admet-1437	649	5	.	.	PROPN
admet-1437	649	6	arce	arce	PROPN
admet-1437	649	7	,	,	PUNCT
admet-1437	649	8	n.	n.	PROPN
admet-1437	649	9	setiawan	setiawan	PROPN
admet-1437	649	10	,	,	PUNCT
admet-1437	649	11	h.r	h.r	PROPN
admet-1437	649	12	.	.	PROPN
admet-1437	649	13	campbell	campbell	PROPN
admet-1437	649	14	,	,	PUNCT
admet-1437	649	15	x.	x.	PROPN
admet-1437	649	16	lu	lu	PROPN
admet-1437	649	17	,	,	PUNCT
admet-1437	649	18	m.j	m.j	PROPN
admet-1437	649	19	.	.	PROPN
admet-1437	649	20	nethercott	nethercott	PROPN
admet-1437	649	21	,	,	PUNCT
admet-1437	649	22	p.	p.	PROPN
admet-1437	649	23	bummer	bummer	PROPN
admet-1437	649	24	,	,	PUNCT
admet-1437	649	25	y.	y.	PROPN
admet-1437	649	26	su	su	PROPN
admet-1437	649	27	,	,	PUNCT
admet-1437	649	28	p.j	p.j	PROPN
admet-1437	649	29	.	.	PROPN
admet-1437	649	30	marsac	marsac	PROPN
admet-1437	649	31	.	.	PUNCT
admet-1437	650	1	toward	toward	ADP
admet-1437	650	2	developing	develop	VERB
admet-1437	650	3	discriminating	discriminate	VERB
admet-1437	650	4	dissolution	dissolution	NOUN
admet-1437	650	5	methods	method	NOUN
admet-1437	650	6	for	for	ADP
admet-1437	650	7	formulations	formulation	NOUN
admet-1437	650	8	containing	contain	VERB
admet-1437	650	9	nanoparticulates	nanoparticulate	NOUN
admet-1437	650	10	in	in	ADP
admet-1437	650	11	solution	solution	NOUN
admet-1437	650	12	:	:	PUNCT
admet-1437	650	13	the	the	DET
admet-1437	650	14	impact	impact	NOUN
admet-1437	650	15	of	of	ADP
admet-1437	650	16	particle	particle	NOUN
admet-1437	650	17	drift	drift	NOUN
admet-1437	650	18	and	and	CCONJ
admet-1437	650	19	drug	drug	NOUN
admet-1437	650	20	activity	activity	NOUN
admet-1437	650	21	in	in	ADP
admet-1437	650	22	solution	solution	NOUN
admet-1437	650	23	.	.	PUNCT
admet-1437	651	1	molecular	molecular	ADJ
admet-1437	651	2	pharmaceutics	pharmaceutic	NOUN
admet-1437	651	3	17	17	NUM
admet-1437	651	4	(	(	PUNCT
admet-1437	651	5	2020	2020	NUM
admet-1437	651	6	)	)	PUNCT
admet-1437	651	7	4125	4125	NUM
admet-1437	651	8	-	-	SYM
admet-1437	651	9	4140	4140	NUM
admet-1437	651	10	.	.	PUNCT
admet-1437	652	1	https://doi.org/10.1021/acs.molpharmaceut.0c00599	https://doi.org/10.1021/acs.molpharmaceut.0c00599	X
admet-1437	652	2	.	.	PUNCT
admet-1437	653	1	[	[	X
admet-1437	653	2	38	38	NUM
admet-1437	653	3	]	]	PUNCT
admet-1437	653	4	h.	h.	PROPN
admet-1437	653	5	tian	tian	PROPN
admet-1437	653	6	,	,	PUNCT
admet-1437	653	7	z.	z.	PROPN
admet-1437	653	8	qin	qin	PROPN
admet-1437	653	9	,	,	PUNCT
admet-1437	653	10	g.	g.	PROPN
admet-1437	653	11	wang	wang	PROPN
admet-1437	653	12	,	,	PUNCT
admet-1437	653	13	x.	x.	PROPN
admet-1437	653	14	yu	yu	PROPN
admet-1437	653	15	,	,	PUNCT
admet-1437	653	16	j.	j.	PROPN
admet-1437	653	17	chen	chen	PROPN
admet-1437	653	18	,	,	PUNCT
admet-1437	653	19	z.	z.	PROPN
admet-1437	653	20	lin	lin	PROPN
admet-1437	653	21	,	,	PUNCT
admet-1437	653	22	s.	s.	PROPN
admet-1437	653	23	du	du	PROPN
admet-1437	653	24	,	,	PUNCT
admet-1437	653	25	h.	h.	PROPN
admet-1437	653	26	yin	yin	PROPN
admet-1437	653	27	,	,	PUNCT
admet-1437	653	28	h.	h.	PROPN
admet-1437	653	29	zou	zou	PROPN
admet-1437	653	30	,	,	PUNCT
admet-1437	653	31	t.	t.	PROPN
admet-1437	653	32	liu	liu	PROPN
admet-1437	653	33	.	.	PUNCT
admet-1437	654	1	consideration	consideration	NOUN
admet-1437	654	2	of	of	ADP
admet-1437	654	3	the	the	DET
admet-1437	654	4	dissolution	dissolution	NOUN
admet-1437	654	5	media	medium	NOUN
admet-1437	654	6	for	for	ADP
admet-1437	654	7	drug	drug	NOUN
admet-1437	654	8	nanocrystal	nanocrystal	ADJ
admet-1437	654	9	evaluation	evaluation	NOUN
admet-1437	654	10	.	.	PUNCT
admet-1437	655	1	powder	powder	NOUN
admet-1437	655	2	technology	technology	NOUN
admet-1437	655	3	392	392	NUM
admet-1437	655	4	(	(	PUNCT
admet-1437	655	5	2021	2021	NUM
admet-1437	655	6	)	)	PUNCT
admet-1437	655	7	179	179	NUM
admet-1437	655	8	-	-	SYM
admet-1437	655	9	190	190	NUM
admet-1437	655	10	.	.	PUNCT
admet-1437	656	1	https://doi.org/10.1016/j.powtec.2021.07.016	https://doi.org/10.1016/j.powtec.2021.07.016	PROPN
admet-1437	656	2	.	.	PUNCT
admet-1437	657	1	[	[	X
admet-1437	657	2	39	39	NUM
admet-1437	657	3	]	]	PUNCT
admet-1437	657	4	a.	a.	NOUN
admet-1437	657	5	elkhabaz	elkhabaz	PROPN
admet-1437	657	6	,	,	PUNCT
admet-1437	657	7	d.e	d.e	PROPN
admet-1437	657	8	.	.	PROPN
admet-1437	657	9	moseson	moseson	PROPN
admet-1437	657	10	,	,	PUNCT
admet-1437	657	11	j.	j.	PROPN
admet-1437	657	12	brouwers	brouwers	PROPN
admet-1437	657	13	,	,	PUNCT
admet-1437	657	14	p.	p.	NOUN
admet-1437	657	15	augustijns	augustijns	NOUN
admet-1437	657	16	,	,	PUNCT
admet-1437	657	17	l.s	l.s	PROPN
admet-1437	657	18	.	.	PROPN
admet-1437	657	19	taylor	taylor	PROPN
admet-1437	657	20	.	.	PUNCT
admet-1437	657	21	interplay	interplay	NOUN
admet-1437	657	22	of	of	ADP
admet-1437	657	23	supersaturation	supersaturation	NOUN
admet-1437	657	24	and	and	CCONJ
admet-1437	657	25	solubilization	solubilization	NOUN
admet-1437	657	26	:	:	PUNCT
admet-1437	657	27	lack	lack	NOUN
admet-1437	657	28	of	of	ADP
admet-1437	657	29	correlation	correlation	NOUN
admet-1437	657	30	between	between	ADP
admet-1437	657	31	concentration	concentration	NOUN
admet-1437	657	32	-	-	PUNCT
admet-1437	657	33	based	base	VERB
admet-1437	657	34	supersaturation	supersaturation	NOUN
admet-1437	657	35	measurements	measurement	NOUN
admet-1437	657	36	and	and	CCONJ
admet-1437	657	37	membrane	membrane	NOUN
admet-1437	657	38	transport	transport	NOUN
admet-1437	657	39	rates	rate	NOUN
admet-1437	657	40	in	in	ADP
admet-1437	657	41	simulated	simulate	VERB
admet-1437	657	42	and	and	CCONJ
admet-1437	657	43	aspirated	aspirate	VERB
admet-1437	657	44	human	human	ADJ
admet-1437	657	45	fluids	fluid	NOUN
admet-1437	657	46	.	.	PUNCT
admet-1437	658	1	molecular	molecular	ADJ
admet-1437	658	2	pharmaceutics	pharmaceutic	NOUN
admet-1437	658	3	16	16	NUM
admet-1437	658	4	(	(	PUNCT
admet-1437	658	5	2019	2019	NUM
admet-1437	658	6	)	)	PUNCT
admet-1437	658	7	5042	5042	NUM
admet-1437	658	8	-	-	SYM
admet-1437	658	9	5053	5053	NUM
admet-1437	658	10	.	.	PUNCT
admet-1437	659	1	https://doi.org/10.1021/acs.molpharmaceut.9b00956	https://doi.org/10.1021/acs.molpharmaceut.9b00956	NOUN
admet-1437	659	2	.	.	PUNCT
admet-1437	660	1	[	[	X
admet-1437	660	2	40	40	NUM
admet-1437	660	3	]	]	PUNCT
admet-1437	660	4	d.	d.	PROPN
admet-1437	660	5	jünemann	jünemann	PROPN
admet-1437	660	6	,	,	PUNCT
admet-1437	660	7	j.	j.	PROPN
admet-1437	660	8	dressman	dressman	PROPN
admet-1437	660	9	.	.	PUNCT
admet-1437	661	1	analytical	analytical	ADJ
admet-1437	661	2	methods	method	NOUN
admet-1437	661	3	for	for	ADP
admet-1437	661	4	dissolution	dissolution	NOUN
admet-1437	661	5	testing	testing	NOUN
admet-1437	661	6	of	of	ADP
admet-1437	661	7	nanosized	nanosized	ADJ
admet-1437	661	8	drugs	drug	NOUN
admet-1437	661	9	.	.	PUNCT
admet-1437	662	1	journal	journal	PROPN
admet-1437	662	2	of	of	ADP
admet-1437	662	3	pharmacy	pharmacy	NOUN
admet-1437	662	4	and	and	CCONJ
admet-1437	662	5	pharmacology	pharmacology	NOUN
admet-1437	662	6	64	64	NUM
admet-1437	662	7	(	(	PUNCT
admet-1437	662	8	2012	2012	NUM
admet-1437	662	9	)	)	PUNCT
admet-1437	662	10	931	931	NUM
admet-1437	662	11	-	-	SYM
admet-1437	662	12	943	943	NUM
admet-1437	662	13	.	.	PUNCT
admet-1437	663	1	https://doi.org/10.1111/j.2042-7158.2012.01520.x	https://doi.org/10.1111/j.2042-7158.2012.01520.x	PROPN
admet-1437	663	2	.	.	PUNCT
admet-1437	664	1	[	[	X
admet-1437	664	2	41	41	NUM
admet-1437	664	3	]	]	PUNCT
admet-1437	664	4	k.	k.	PROPN
admet-1437	664	5	anhalt	anhalt	PROPN
admet-1437	664	6	,	,	PUNCT
admet-1437	664	7	s.	s.	PROPN
admet-1437	664	8	geissler	geissler	PROPN
admet-1437	664	9	,	,	PUNCT
admet-1437	664	10	m.	m.	NOUN
admet-1437	664	11	harms	harm	NOUN
admet-1437	664	12	,	,	PUNCT
admet-1437	664	13	m.	m.	NOUN
admet-1437	664	14	weigandt	weigandt	PROPN
admet-1437	664	15	,	,	PUNCT
admet-1437	664	16	g.	g.	PROPN
admet-1437	664	17	fricker	fricker	PROPN
admet-1437	664	18	.	.	PUNCT
admet-1437	665	1	development	development	NOUN
admet-1437	665	2	of	of	ADP
admet-1437	665	3	a	a	DET
admet-1437	665	4	new	new	ADJ
admet-1437	665	5	method	method	NOUN
admet-1437	665	6	to	to	PART
admet-1437	665	7	assess	assess	VERB
admet-1437	665	8	nanocrystal	nanocrystal	ADJ
admet-1437	665	9	dissolution	dissolution	NOUN
admet-1437	665	10	based	base	VERB
admet-1437	665	11	on	on	ADP
admet-1437	665	12	light	light	ADJ
admet-1437	665	13	scattering	scattering	NOUN
admet-1437	665	14	.	.	PUNCT
admet-1437	666	1	pharmaceutical	pharmaceutical	ADJ
admet-1437	666	2	research	research	NOUN
admet-1437	666	3	29	29	NUM
admet-1437	666	4	(	(	PUNCT
admet-1437	666	5	2012	2012	NUM
admet-1437	666	6	)	)	PUNCT
admet-1437	666	7	2887	2887	NUM
admet-1437	666	8	-	-	SYM
admet-1437	666	9	2901	2901	NUM
admet-1437	666	10	.	.	PUNCT
admet-1437	667	1	https://doi.org/10.1007/s11095-012-0795-4	https://doi.org/10.1007/s11095-012-0795-4	NOUN
admet-1437	667	2	.	.	PUNCT
admet-1437	668	1	[	[	X
admet-1437	668	2	42	42	NUM
admet-1437	668	3	]	]	PUNCT
admet-1437	668	4	b.	b.	PROPN
admet-1437	668	5	van	van	PROPN
admet-1437	668	6	eerdenbrugh	eerdenbrugh	PROPN
admet-1437	668	7	,	,	PUNCT
admet-1437	668	8	d.e	d.e	PROPN
admet-1437	668	9	.	.	PROPN
admet-1437	668	10	alonzo	alonzo	PROPN
admet-1437	668	11	,	,	PUNCT
admet-1437	668	12	l.s	l.s	PROPN
admet-1437	668	13	.	.	PROPN
admet-1437	668	14	taylor	taylor	PROPN
admet-1437	668	15	.	.	PUNCT
admet-1437	668	16	influence	influence	NOUN
admet-1437	668	17	of	of	ADP
admet-1437	668	18	particle	particle	NOUN
admet-1437	668	19	size	size	NOUN
admet-1437	668	20	on	on	ADP
admet-1437	668	21	the	the	DET
admet-1437	668	22	ultraviolet	ultraviolet	NOUN
admet-1437	668	23	spectrum	spectrum	NOUN
admet-1437	668	24	of	of	ADP
admet-1437	668	25	particulate	particulate	NOUN
admet-1437	668	26	-	-	PUNCT
admet-1437	668	27	containing	contain	VERB
admet-1437	668	28	solutions	solution	NOUN
admet-1437	668	29	:	:	PUNCT
admet-1437	668	30	implications	implication	NOUN
admet-1437	668	31	for	for	ADP
admet-1437	668	32	in	in	ADP
admet-1437	668	33	-	-	PUNCT
admet-1437	668	34	situ	situ	NOUN
admet-1437	668	35	concentration	concentration	NOUN
admet-1437	668	36	monitoring	monitoring	NOUN
admet-1437	668	37	using	use	VERB
admet-1437	668	38	uv	uv	NOUN
admet-1437	668	39	/	/	SYM
admet-1437	668	40	vis	vis	X
admet-1437	668	41	fiberoptic	fiberoptic	ADJ
admet-1437	668	42	probes	probe	NOUN
admet-1437	668	43	.	.	PUNCT
admet-1437	669	1	pharmaceutical	pharmaceutical	ADJ
admet-1437	669	2	research	research	NOUN
admet-1437	669	3	28	28	NUM
admet-1437	669	4	(	(	PUNCT
admet-1437	669	5	2011	2011	NUM
admet-1437	669	6	)	)	PUNCT
admet-1437	669	7	1643	1643	NUM
admet-1437	669	8	-	-	SYM
admet-1437	669	9	1652	1652	NUM
admet-1437	669	10	.	.	PUNCT
admet-1437	670	1	https://doi.org/10.1007/s11095-0110399-4	https://doi.org/10.1007/s11095-0110399-4	PROPN
admet-1437	670	2	.	.	PUNCT
admet-1437	671	1	[	[	X
admet-1437	671	2	43	43	NUM
admet-1437	671	3	]	]	X
admet-1437	671	4	b.	b.	PROPN
admet-1437	671	5	van	van	PROPN
admet-1437	671	6	eerdenbrugh	eerdenbrugh	PROPN
admet-1437	671	7	,	,	PUNCT
admet-1437	671	8	j.	j.	PROPN
admet-1437	671	9	vermant	vermant	PROPN
admet-1437	671	10	,	,	PUNCT
admet-1437	671	11	j.a	j.a	PROPN
admet-1437	671	12	.	.	PROPN
admet-1437	671	13	martens	martens	PROPN
admet-1437	671	14	,	,	PUNCT
admet-1437	671	15	l.	l.	PROPN
admet-1437	671	16	froyen	froyen	PROPN
admet-1437	671	17	,	,	PUNCT
admet-1437	671	18	j.	j.	PROPN
admet-1437	671	19	van	van	PROPN
admet-1437	671	20	humbeeck	humbeeck	PROPN
admet-1437	671	21	,	,	PUNCT
admet-1437	671	22	g.	g.	PROPN
admet-1437	671	23	van	van	PROPN
admet-1437	671	24	den	den	PROPN
admet-1437	671	25	mooter	mooter	NOUN
admet-1437	671	26	,	,	PUNCT
admet-1437	671	27	p.	p.	NOUN
admet-1437	671	28	augustijns	augustijns	NOUN
admet-1437	671	29	.	.	PUNCT
admet-1437	672	1	solubility	solubility	NOUN
admet-1437	672	2	increases	increase	NOUN
admet-1437	672	3	associated	associate	VERB
admet-1437	672	4	with	with	ADP
admet-1437	672	5	crystalline	crystalline	ADJ
admet-1437	672	6	drug	drug	NOUN
admet-1437	672	7	nanoparticles	nanoparticle	NOUN
admet-1437	672	8	:	:	PUNCT
admet-1437	672	9	methodologies	methodology	NOUN
admet-1437	672	10	and	and	CCONJ
admet-1437	672	11	significance	significance	NOUN
admet-1437	672	12	.	.	PUNCT
admet-1437	673	1	molecular	molecular	ADJ
admet-1437	673	2	pharmaceutics	pharmaceutic	NOUN
admet-1437	673	3	7	7	NUM
admet-1437	673	4	(	(	PUNCT
admet-1437	673	5	2010	2010	NUM
admet-1437	673	6	)	)	PUNCT
admet-1437	673	7	1858	1858	NUM
admet-1437	673	8	-	-	SYM
admet-1437	673	9	1870	1870	NUM
admet-1437	673	10	.	.	PUNCT
admet-1437	674	1	https://doi.org/10.1021/mp100209b	https://doi.org/10.1021/mp100209b	PROPN
admet-1437	674	2	.	.	PUNCT
admet-1437	675	1	[	[	X
admet-1437	675	2	44	44	NUM
admet-1437	675	3	]	]	SYM
admet-1437	675	4	s.b	s.b	PROPN
admet-1437	675	5	.	.	PROPN
admet-1437	675	6	murdande	murdande	PROPN
admet-1437	675	7	,	,	PUNCT
admet-1437	675	8	d.a	d.a	PROPN
admet-1437	675	9	.	.	PROPN
admet-1437	675	10	shah	shah	PROPN
admet-1437	675	11	,	,	PUNCT
admet-1437	675	12	r.h	r.h	PROPN
admet-1437	675	13	.	.	PROPN
admet-1437	675	14	dave	dave	PROPN
admet-1437	675	15	.	.	PUNCT
admet-1437	676	1	impact	impact	NOUN
admet-1437	676	2	of	of	ADP
admet-1437	676	3	nanosizing	nanosizing	NOUN
admet-1437	676	4	on	on	ADP
admet-1437	676	5	solubility	solubility	NOUN
admet-1437	676	6	and	and	CCONJ
admet-1437	676	7	dissolution	dissolution	NOUN
admet-1437	676	8	rate	rate	NOUN
admet-1437	676	9	of	of	ADP
admet-1437	676	10	poorly	poorly	ADV
admet-1437	676	11	soluble	soluble	ADJ
admet-1437	676	12	pharmaceuticals	pharmaceutical	NOUN
admet-1437	676	13	.	.	PUNCT
admet-1437	677	1	journal	journal	NOUN
admet-1437	677	2	of	of	ADP
admet-1437	677	3	pharmaceutical	pharmaceutical	PROPN
admet-1437	677	4	sciences	science	NOUN
admet-1437	677	5	104	104	NUM
admet-1437	677	6	(	(	PUNCT
admet-1437	677	7	2015	2015	NUM
admet-1437	677	8	)	)	PUNCT
admet-1437	677	9	2094	2094	NUM
admet-1437	677	10	-	-	SYM
admet-1437	677	11	2102	2102	NUM
admet-1437	677	12	.	.	PUNCT
admet-1437	678	1	https://doi.org/10.1002/jps.24426	https://doi.org/10.1002/jps.24426	PROPN
admet-1437	678	2	.	.	PUNCT
admet-1437	679	1	[	[	X
admet-1437	679	2	45	45	NUM
admet-1437	679	3	]	]	PUNCT
admet-1437	679	4	m.	m.	NOUN
admet-1437	679	5	colombo	colombo	NOUN
admet-1437	679	6	,	,	PUNCT
admet-1437	679	7	s.	s.	PROPN
admet-1437	679	8	staufenbiel	staufenbiel	PROPN
admet-1437	679	9	,	,	PUNCT
admet-1437	679	10	e.	e.	PROPN
admet-1437	679	11	rühl	rühl	PROPN
admet-1437	679	12	,	,	PUNCT
admet-1437	679	13	r.	r.	PROPN
admet-1437	679	14	bodmeier	bodmeier	NOUN
admet-1437	679	15	.	.	PUNCT
admet-1437	680	1	in	in	ADP
admet-1437	680	2	situ	situ	ADJ
admet-1437	680	3	determination	determination	NOUN
admet-1437	680	4	of	of	ADP
admet-1437	680	5	the	the	DET
admet-1437	680	6	saturation	saturation	NOUN
admet-1437	680	7	solubility	solubility	NOUN
admet-1437	680	8	of	of	ADP
admet-1437	680	9	nanocrystals	nanocrystal	NOUN
admet-1437	680	10	of	of	ADP
admet-1437	680	11	poorly	poorly	ADV
admet-1437	680	12	soluble	soluble	ADJ
admet-1437	680	13	drugs	drug	NOUN
admet-1437	680	14	for	for	ADP
admet-1437	680	15	dermal	dermal	ADJ
admet-1437	680	16	application	application	NOUN
admet-1437	680	17	.	.	PUNCT
admet-1437	681	1	international	international	ADJ
admet-1437	681	2	journal	journal	PROPN
admet-1437	681	3	of	of	ADP
admet-1437	681	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	681	5	521	521	NUM
admet-1437	681	6	(	(	PUNCT
admet-1437	681	7	2017	2017	NUM
admet-1437	681	8	)	)	PUNCT
admet-1437	681	9	156	156	NUM
admet-1437	681	10	-	-	SYM
admet-1437	681	11	166	166	NUM
admet-1437	681	12	.	.	PUNCT
admet-1437	682	1	https://doi.org/10.1016/j.ijpharm.2017.02.030	https://doi.org/10.1016/j.ijpharm.2017.02.030	NUM
admet-1437	682	2	.	.	PUNCT
admet-1437	683	1	[	[	X
admet-1437	683	2	46	46	NUM
admet-1437	683	3	]	]	PUNCT
admet-1437	683	4	m.	m.	NOUN
admet-1437	683	5	colombo	colombo	NOUN
admet-1437	683	6	,	,	PUNCT
admet-1437	683	7	c.	c.	PROPN
admet-1437	683	8	minussi	minussi	PROPN
admet-1437	683	9	,	,	PUNCT
admet-1437	683	10	s.	s.	PROPN
admet-1437	683	11	orthmann	orthmann	PROPN
admet-1437	683	12	,	,	PUNCT
admet-1437	683	13	s.	s.	PROPN
admet-1437	683	14	staufenbiel	staufenbiel	PROPN
admet-1437	683	15	,	,	PUNCT
admet-1437	683	16	r.	r.	PROPN
admet-1437	683	17	bodmeier	bodmeier	PROPN
admet-1437	683	18	.	.	PUNCT
admet-1437	684	1	preparation	preparation	NOUN
admet-1437	684	2	of	of	ADP
admet-1437	684	3	amorphous	amorphous	ADJ
admet-1437	684	4	indomethacin	indomethacin	NOUN
admet-1437	684	5	nanoparticles	nanoparticle	NOUN
admet-1437	684	6	by	by	ADP
admet-1437	684	7	aqueous	aqueous	ADJ
admet-1437	684	8	wet	wet	ADJ
admet-1437	684	9	bead	bead	NOUN
admet-1437	684	10	milling	milling	NOUN
admet-1437	684	11	and	and	CCONJ
admet-1437	684	12	in	in	ADP
admet-1437	684	13	situ	situ	ADJ
admet-1437	684	14	measurement	measurement	NOUN
admet-1437	684	15	of	of	ADP
admet-1437	684	16	their	their	PRON
admet-1437	684	17	increased	increase	VERB
admet-1437	684	18	saturation	saturation	NOUN
admet-1437	684	19	solubility	solubility	NOUN
admet-1437	684	20	.	.	PUNCT
admet-1437	685	1	european	european	PROPN
admet-1437	685	2	journal	journal	PROPN
admet-1437	685	3	of	of	ADP
admet-1437	685	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	685	5	and	and	CCONJ
admet-1437	685	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1437	685	7	125	125	NUM
admet-1437	685	8	(	(	PUNCT
admet-1437	685	9	2018	2018	NUM
admet-1437	685	10	)	)	PUNCT
admet-1437	685	11	159	159	NUM
admet-1437	685	12	-	-	SYM
admet-1437	685	13	168	168	NUM
admet-1437	685	14	.	.	PUNCT
admet-1437	686	1	https://doi.org/10.1016/j.ejpb.2018.01.013	https://doi.org/10.1016/j.ejpb.2018.01.013	PROPN
admet-1437	686	2	.	.	PUNCT
admet-1437	687	1	[	[	X
admet-1437	687	2	47	47	NUM
admet-1437	687	3	]	]	X
admet-1437	687	4	a.t.k	a.t.k	PROPN
admet-1437	687	5	.	.	PUNCT
admet-1437	687	6	lu	lu	PROPN
admet-1437	687	7	,	,	PUNCT
admet-1437	687	8	m.e	m.e	PROPN
admet-1437	687	9	.	.	PROPN
admet-1437	687	10	frisella	frisella	PROPN
admet-1437	687	11	,	,	PUNCT
admet-1437	687	12	k.c	k.c	PROPN
admet-1437	687	13	.	.	PROPN
admet-1437	687	14	johnson	johnson	PROPN
admet-1437	687	15	.	.	PUNCT
admet-1437	688	1	dissolution	dissolution	PROPN
admet-1437	688	2	modeling	modeling	NOUN
admet-1437	688	3	:	:	PUNCT
admet-1437	688	4	factors	factor	NOUN
admet-1437	688	5	affecting	affect	VERB
admet-1437	688	6	the	the	DET
admet-1437	688	7	dissolution	dissolution	NOUN
admet-1437	688	8	rates	rate	NOUN
admet-1437	688	9	of	of	ADP
admet-1437	688	10	polydisperse	polydisperse	NOUN
admet-1437	688	11	powders	powder	NOUN
admet-1437	688	12	.	.	PUNCT
admet-1437	689	1	pharmceutical	pharmceutical	ADJ
admet-1437	689	2	research	research	NOUN
admet-1437	689	3	10	10	NUM
admet-1437	689	4	(	(	PUNCT
admet-1437	689	5	1993	1993	NUM
admet-1437	689	6	)	)	PUNCT
admet-1437	689	7	1308	1308	NUM
admet-1437	689	8	-	-	SYM
admet-1437	689	9	1314	1314	NUM
admet-1437	689	10	.	.	PUNCT
admet-1437	690	1	https://doi.org/10.1023/a:1018917729477	https://doi.org/10.1023/a:1018917729477	NOUN
admet-1437	690	2	.	.	PUNCT
admet-1437	691	1	[	[	X
admet-1437	691	2	48	48	NUM
admet-1437	691	3	]	]	PUNCT
admet-1437	691	4	j.	j.	PROPN
admet-1437	691	5	wang	wang	PROPN
admet-1437	691	6	,	,	PUNCT
admet-1437	691	7	d.r	d.r	PROPN
admet-1437	691	8	.	.	PROPN
admet-1437	691	9	flanagan	flanagan	PROPN
admet-1437	691	10	.	.	PUNCT
admet-1437	692	1	general	general	ADJ
admet-1437	692	2	solution	solution	NOUN
admet-1437	692	3	for	for	ADP
admet-1437	692	4	diffusion	diffusion	NOUN
admet-1437	692	5	-	-	PUNCT
admet-1437	692	6	controlled	control	VERB
admet-1437	692	7	dissolution	dissolution	NOUN
admet-1437	692	8	of	of	ADP
admet-1437	692	9	spherical	spherical	ADJ
admet-1437	692	10	particles	particle	NOUN
admet-1437	692	11	.	.	PUNCT
admet-1437	693	1	1	1	X
admet-1437	693	2	.	.	X
admet-1437	693	3	theory	theory	NOUN
admet-1437	693	4	.	.	PUNCT
admet-1437	694	1	journal	journal	PROPN
admet-1437	694	2	of	of	ADP
admet-1437	694	3	pharmaceutical	pharmaceutical	PROPN
admet-1437	694	4	sciences	science	NOUN
admet-1437	694	5	88	88	NUM
admet-1437	694	6	(	(	PUNCT
admet-1437	694	7	1999	1999	NUM
admet-1437	694	8	)	)	PUNCT
admet-1437	694	9	731	731	NUM
admet-1437	694	10	-	-	SYM
admet-1437	694	11	738	738	NUM
admet-1437	694	12	.	.	PUNCT
admet-1437	695	1	https://doi.org/10.1021/js980236p	https://doi.org/10.1021/js980236p	NOUN
admet-1437	695	2	.	.	PUNCT
admet-1437	696	1	[	[	X
admet-1437	696	2	49	49	NUM
admet-1437	696	3	]	]	PUNCT
admet-1437	696	4	j.	j.	PROPN
admet-1437	696	5	wang	wang	PROPN
admet-1437	696	6	,	,	PUNCT
admet-1437	696	7	d.r	d.r	PROPN
admet-1437	696	8	.	.	PROPN
admet-1437	696	9	flanagan	flanagan	PROPN
admet-1437	696	10	.	.	PUNCT
admet-1437	696	11	general	general	ADJ
admet-1437	696	12	solution	solution	NOUN
admet-1437	696	13	for	for	ADP
admet-1437	696	14	diffusion	diffusion	NOUN
admet-1437	696	15	-	-	PUNCT
admet-1437	696	16	controlled	control	VERB
admet-1437	696	17	dissolution	dissolution	NOUN
admet-1437	696	18	of	of	ADP
admet-1437	696	19	spherical	spherical	ADJ
admet-1437	696	20	particles	particle	NOUN
admet-1437	696	21	.	.	PUNCT
admet-1437	697	1	2	2	X
admet-1437	697	2	.	.	X
admet-1437	697	3	evaluation	evaluation	NOUN
admet-1437	697	4	of	of	ADP
admet-1437	697	5	experimental	experimental	ADJ
admet-1437	697	6	data	datum	NOUN
admet-1437	697	7	.	.	PUNCT
admet-1437	698	1	journal	journal	PROPN
admet-1437	698	2	of	of	ADP
admet-1437	698	3	pharmaceutical	pharmaceutical	PROPN
admet-1437	698	4	sciences	science	NOUN
admet-1437	698	5	91	91	NUM
admet-1437	698	6	(	(	PUNCT
admet-1437	698	7	2002	2002	NUM
admet-1437	698	8	)	)	PUNCT
admet-1437	698	9	534	534	NUM
admet-1437	698	10	-	-	SYM
admet-1437	698	11	542	542	NUM
admet-1437	698	12	.	.	PUNCT
admet-1437	699	1	https://doi.org/10.1002/jps.10039	https://doi.org/10.1002/jps.10039	NOUN
admet-1437	699	2	.	.	PUNCT
admet-1437	700	1	[	[	X
admet-1437	700	2	50	50	NUM
admet-1437	700	3	]	]	X
admet-1437	700	4	y.	y.	PROPN
admet-1437	700	5	wang	wang	PROPN
admet-1437	700	6	,	,	PUNCT
admet-1437	700	7	b.	b.	PROPN
admet-1437	700	8	abrahamsson	abrahamsson	PROPN
admet-1437	700	9	,	,	PUNCT
admet-1437	700	10	l.	l.	PROPN
admet-1437	700	11	lindfors	lindfors	PROPN
admet-1437	700	12	,	,	PUNCT
admet-1437	700	13	j.g.brasseur	j.g.brasseur	PROPN
admet-1437	700	14	.	.	PUNCT
admet-1437	701	1	analysis	analysis	NOUN
admet-1437	701	2	of	of	ADP
admet-1437	701	3	diffusion	diffusion	NOUN
admet-1437	701	4	-	-	PUNCT
admet-1437	701	5	controlled	control	VERB
admet-1437	701	6	dissolution	dissolution	NOUN
admet-1437	701	7	from	from	ADP
admet-1437	701	8	polydisperse	polydisperse	NOUN
admet-1437	701	9	collections	collection	NOUN
admet-1437	701	10	of	of	ADP
admet-1437	701	11	drug	drug	NOUN
admet-1437	701	12	particles	particle	NOUN
admet-1437	701	13	with	with	ADP
admet-1437	701	14	an	an	DET
admet-1437	701	15	assessed	assessed	ADJ
admet-1437	701	16	mathematical	mathematical	ADJ
admet-1437	701	17	model	model	NOUN
admet-1437	701	18	.	.	PUNCT
admet-1437	702	1	journal	journal	PROPN
admet-1437	702	2	of	of	ADP
admet-1437	702	3	pharmaceutical	pharmaceutical	PROPN
admet-1437	702	4	sciences	science	NOUN
admet-1437	702	5	104	104	NUM
admet-1437	702	6	(	(	PUNCT
admet-1437	702	7	2015	2015	NUM
admet-1437	702	8	)	)	PUNCT
admet-1437	702	9	2998	2998	NUM
admet-1437	702	10	-	-	SYM
admet-1437	702	11	3017	3017	NUM
admet-1437	702	12	.	.	PUNCT
admet-1437	703	1	https://doi.org/10.1002/jps.24472	https://doi.org/10.1002/jps.24472	PROPN
admet-1437	703	2	.	.	PUNCT
admet-1437	704	1	[	[	X
admet-1437	704	2	51	51	NUM
admet-1437	704	3	]	]	PUNCT
admet-1437	704	4	m.	m.	NOUN
admet-1437	704	5	abrami	abrami	PROPN
admet-1437	704	6	,	,	PUNCT
admet-1437	704	7	l.	l.	PROPN
admet-1437	704	8	grassi	grassi	PROPN
admet-1437	704	9	,	,	PUNCT
admet-1437	704	10	r.	r.	PROPN
admet-1437	704	11	di	di	PROPN
admet-1437	704	12	vittorio	vittorio	PROPN
admet-1437	704	13	,	,	PUNCT
admet-1437	704	14	d.	d.	PROPN
admet-1437	704	15	hasa	hasa	PROPN
admet-1437	704	16	,	,	PUNCT
admet-1437	704	17	b.	b.	PROPN
admet-1437	704	18	perissutti	perissutti	PROPN
admet-1437	704	19	,	,	PUNCT
admet-1437	704	20	d.	d.	PROPN
admet-1437	704	21	voinovich	voinovich	PROPN
admet-1437	704	22	,	,	PUNCT
admet-1437	704	23	g.	g.	PROPN
admet-1437	704	24	grassi	grassi	PROPN
admet-1437	704	25	,	,	PUNCT
admet-1437	704	26	i.	i.	PROPN
admet-1437	704	27	colombo	colombo	PROPN
admet-1437	704	28	,	,	PUNCT
admet-1437	704	29	m.	m.	NOUN
admet-1437	704	30	grassi	grassi	PROPN
admet-1437	704	31	.	.	PUNCT
admet-1437	705	1	dissolution	dissolution	NOUN
admet-1437	705	2	of	of	ADP
admet-1437	705	3	an	an	DET
admet-1437	705	4	ensemble	ensemble	NOUN
admet-1437	705	5	of	of	ADP
admet-1437	705	6	differently	differently	ADV
admet-1437	705	7	shaped	shape	VERB
admet-1437	705	8	poly	poly	ADJ
admet-1437	705	9	-	-	PUNCT
admet-1437	705	10	dispersed	disperse	VERB
admet-1437	705	11	drug	drug	NOUN
admet-1437	705	12	particles	particle	NOUN
admet-1437	705	13	undergoing	undergo	VERB
admet-1437	705	14	solubility	solubility	NOUN
admet-1437	705	15	https://doi.org/10.1016/j.ijpharm.2018.12.086	https://doi.org/10.1016/j.ijpharm.2018.12.086	ADJ
admet-1437	705	16	https://doi.org/10.1021/acs.molpharmaceut.0c00599	https://doi.org/10.1021/acs.molpharmaceut.0c00599	PROPN
admet-1437	705	17	https://doi.org/10.1016/j.powtec.2021.07.016	https://doi.org/10.1016/j.powtec.2021.07.016	PROPN
admet-1437	706	1	https://doi.org/10.1021/acs.molpharmaceut.9b00956	https://doi.org/10.1021/acs.molpharmaceut.9b00956	PRON
admet-1437	706	2	https://doi.org/10.1111/j.2042-7158.2012.01520.x	https://doi.org/10.1111/j.2042-7158.2012.01520.x	NOUN
admet-1437	706	3	https://doi.org/10.1007/s11095-012-0795-4	https://doi.org/10.1007/s11095-012-0795-4	NUM
admet-1437	706	4	https://doi.org/10.1007/s11095-011-0399-4	https://doi.org/10.1007/s11095-011-0399-4	NUM
admet-1437	706	5	https://doi.org/10.1007/s11095-011-0399-4	https://doi.org/10.1007/s11095-011-0399-4	NUM
admet-1437	706	6	https://doi.org/10.1021/mp100209b	https://doi.org/10.1021/mp100209b	VERB
admet-1437	706	7	https://doi.org/10.1002/jps.24426	https://doi.org/10.1002/jps.24426	PROPN
admet-1437	706	8	https://doi.org/10.1002/jps.24426	https://doi.org/10.1002/jps.24426	PROPN
admet-1437	706	9	https://doi.org/10.1016/j.ijpharm.2017.02.030	https://doi.org/10.1016/j.ijpharm.2017.02.030	PROPN
admet-1437	706	10	https://doi.org/10.1016/j.ejpb.2018.01.013	https://doi.org/10.1016/j.ejpb.2018.01.013	PROPN
admet-1437	706	11	https://doi.org/10.1023/a:1018917729477	https://doi.org/10.1023/a:1018917729477	PROPN
admet-1437	706	12	https://doi.org/10.1023/a:1018917729477	https://doi.org/10.1023/a:1018917729477	PROPN
admet-1437	706	13	https://doi.org/10.1021/js980236p	https://doi.org/10.1021/js980236p	NOUN
admet-1437	706	14	https://doi.org/10.1002/jps.10039	https://doi.org/10.1002/jps.10039	PROPN
admet-1437	706	15	https://doi.org/10.1002/jps.24472	https://doi.org/10.1002/jps.24472	PROPN
admet-1437	706	16	admet	admet	PROPN
admet-1437	706	17	&	&	CCONJ
admet-1437	706	18	dmpk	dmpk	PROPN
admet-1437	706	19	10(4	10(4	NUM
admet-1437	706	20	)	)	PUNCT
admet-1437	706	21	(	(	PUNCT
admet-1437	706	22	2022	2022	NUM
admet-1437	706	23	)	)	PUNCT
admet-1437	706	24	253	253	NUM
admet-1437	706	25	-	-	SYM
admet-1437	706	26	287	287	NUM
admet-1437	706	27	modeling	modeling	NOUN
admet-1437	706	28	of	of	ADP
admet-1437	706	29	drug	drug	NOUN
admet-1437	706	30	nanocrystals	nanocrystal	NOUN
admet-1437	706	31	dissolution	dissolution	NOUN
admet-1437	706	32	doi	doi	PROPN
admet-1437	706	33	:	:	PUNCT
admet-1437	706	34	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	706	35	285	285	NUM
admet-1437	706	36	reduction	reduction	NOUN
admet-1437	706	37	:	:	PUNCT
admet-1437	706	38	mathematical	mathematical	ADJ
admet-1437	706	39	modelling	modelling	NOUN
admet-1437	706	40	.	.	PUNCT
admet-1437	707	1	admet	admet	PROPN
admet-1437	707	2	&	&	CCONJ
admet-1437	707	3	dmpk	dmpk	PROPN
admet-1437	707	4	8	8	NUM
admet-1437	707	5	(	(	PUNCT
admet-1437	707	6	2020	2020	NUM
admet-1437	707	7	)	)	PUNCT
admet-1437	707	8	297	297	NUM
admet-1437	707	9	-	-	SYM
admet-1437	707	10	313	313	NUM
admet-1437	707	11	.	.	PUNCT
admet-1437	707	12	http://dx.doi.org/10.5599/admet.841	http://dx.doi.org/10.5599/admet.841	PROPN
admet-1437	707	13	.	.	PUNCT
admet-1437	708	1	[	[	X
admet-1437	708	2	52	52	NUM
admet-1437	708	3	]	]	X
admet-1437	708	4	y.	y.	PROPN
admet-1437	708	5	gao	gao	PROPN
admet-1437	708	6	,	,	PUNCT
admet-1437	708	7	b.	b.	PROPN
admet-1437	708	8	glennon	glennon	PROPN
admet-1437	708	9	,	,	PUNCT
admet-1437	708	10	y.	y.	PROPN
admet-1437	708	11	he	he	PRON
admet-1437	708	12	,	,	PUNCT
admet-1437	708	13	p.	p.	NOUN
admet-1437	708	14	donnellan	donnellan	NOUN
admet-1437	708	15	.	.	PUNCT
admet-1437	709	1	dissolution	dissolution	PROPN
admet-1437	709	2	kinetics	kinetic	NOUN
admet-1437	709	3	of	of	ADP
admet-1437	709	4	a	a	DET
admet-1437	709	5	bcs	bcs	NOUN
admet-1437	709	6	class	class	NOUN
admet-1437	709	7	ii	ii	PROPN
admet-1437	709	8	active	active	ADJ
admet-1437	709	9	pharmaceutical	pharmaceutical	ADJ
admet-1437	709	10	ingredient	ingredient	NOUN
admet-1437	709	11	:	:	PUNCT
admet-1437	709	12	diffusion	diffusion	NOUN
admet-1437	709	13	-	-	PUNCT
admet-1437	709	14	based	base	VERB
admet-1437	709	15	model	model	NOUN
admet-1437	709	16	validation	validation	NOUN
admet-1437	709	17	and	and	CCONJ
admet-1437	709	18	prediction	prediction	NOUN
admet-1437	709	19	.	.	PUNCT
admet-1437	710	1	acs	acs	PROPN
admet-1437	710	2	omega	omega	NOUN
admet-1437	710	3	6	6	NUM
admet-1437	710	4	(	(	PUNCT
admet-1437	710	5	2021	2021	NUM
admet-1437	710	6	)	)	PUNCT
admet-1437	710	7	8056	8056	NUM
admet-1437	710	8	-	-	SYM
admet-1437	710	9	8067	8067	NUM
admet-1437	710	10	.	.	PUNCT
admet-1437	711	1	https://doi.org/10.1021/acsomega.0c05558	https://doi.org/10.1021/acsomega.0c05558	NOUN
admet-1437	711	2	.	.	PUNCT
admet-1437	712	1	[	[	X
admet-1437	712	2	53	53	NUM
admet-1437	712	3	]	]	X
admet-1437	712	4	d.r	d.r	PROPN
admet-1437	712	5	.	.	PROPN
admet-1437	712	6	ely	ely	PROPN
admet-1437	712	7	,	,	PUNCT
admet-1437	712	8	r.e	r.e	PROPN
admet-1437	712	9	.	.	PROPN
admet-1437	712	10	garcía	garcía	PROPN
admet-1437	712	11	,	,	PUNCT
admet-1437	712	12	m.	m.	NOUN
admet-1437	712	13	thommes	thomme	NOUN
admet-1437	712	14	.	.	PUNCT
admet-1437	713	1	ostwald	ostwald	ADJ
admet-1437	713	2	–	–	PUNCT
admet-1437	713	3	freundlich	freundlich	ADJ
admet-1437	713	4	diffusion	diffusion	NOUN
admet-1437	713	5	-	-	PUNCT
admet-1437	713	6	limited	limit	VERB
admet-1437	713	7	dissolution	dissolution	NOUN
admet-1437	713	8	kinetics	kinetic	NOUN
admet-1437	713	9	of	of	ADP
admet-1437	713	10	nanoparticles	nanoparticle	NOUN
admet-1437	713	11	.	.	PUNCT
admet-1437	714	1	powder	powder	NOUN
admet-1437	714	2	technology	technology	NOUN
admet-1437	714	3	257	257	NUM
admet-1437	714	4	(	(	PUNCT
admet-1437	714	5	2014	2014	NUM
admet-1437	714	6	)	)	PUNCT
admet-1437	714	7	120	120	NUM
admet-1437	714	8	-	-	SYM
admet-1437	714	9	123	123	NUM
admet-1437	714	10	.	.	PUNCT
admet-1437	714	11	https://doi.org/10.1016/j.powtec.2014.01.095	https://doi.org/10.1016/j.powtec.2014.01.095	PROPN
admet-1437	714	12	.	.	PUNCT
admet-1437	715	1	[	[	X
admet-1437	715	2	54	54	NUM
admet-1437	715	3	]	]	X
admet-1437	715	4	k.c	k.c	PROPN
admet-1437	715	5	.	.	PROPN
admet-1437	715	6	johnson	johnson	PROPN
admet-1437	715	7	.	.	PUNCT
admet-1437	716	1	comparison	comparison	NOUN
admet-1437	716	2	of	of	ADP
admet-1437	716	3	methods	method	NOUN
admet-1437	716	4	for	for	ADP
admet-1437	716	5	predicting	predict	VERB
admet-1437	716	6	dissolution	dissolution	NOUN
admet-1437	716	7	and	and	CCONJ
admet-1437	716	8	the	the	DET
admet-1437	716	9	theoretical	theoretical	ADJ
admet-1437	716	10	implications	implication	NOUN
admet-1437	716	11	of	of	ADP
admet-1437	716	12	particle	particle	NOUN
admet-1437	716	13	-	-	PUNCT
admet-1437	716	14	size	size	NOUN
admet-1437	716	15	-	-	PUNCT
admet-1437	716	16	dependent	dependent	ADJ
admet-1437	716	17	solubility	solubility	NOUN
admet-1437	716	18	.	.	PUNCT
admet-1437	717	1	journal	journal	PROPN
admet-1437	717	2	of	of	ADP
admet-1437	717	3	pharmaceutical	pharmaceutical	PROPN
admet-1437	717	4	sciences	science	NOUN
admet-1437	717	5	101	101	NUM
admet-1437	717	6	(	(	PUNCT
admet-1437	717	7	2012	2012	NUM
admet-1437	717	8	)	)	PUNCT
admet-1437	717	9	681	681	NUM
admet-1437	717	10	-	-	NUM
admet-1437	717	11	689	689	NUM
admet-1437	717	12	.	.	PUNCT
admet-1437	718	1	https://doi.org/10.1002/jps.22778	https://doi.org/10.1002/jps.22778	NOUN
admet-1437	718	2	.	.	PUNCT
admet-1437	719	1	[	[	X
admet-1437	719	2	55	55	NUM
admet-1437	719	3	]	]	X
admet-1437	719	4	c.	c.	PROPN
admet-1437	719	5	parks	parks	PROPN
admet-1437	719	6	,	,	PUNCT
admet-1437	719	7	a.	a.	PROPN
admet-1437	719	8	koswara	koswara	PROPN
admet-1437	719	9	,	,	PUNCT
admet-1437	719	10	h.h.tung	h.h.tung	PROPN
admet-1437	719	11	,	,	PUNCT
admet-1437	719	12	n.k	n.k	PROPN
admet-1437	719	13	.	.	PROPN
admet-1437	719	14	nere	nere	PROPN
admet-1437	719	15	,	,	PUNCT
admet-1437	719	16	s.	s.	PROPN
admet-1437	719	17	bordawekar	bordawekar	PROPN
admet-1437	719	18	,	,	PUNCT
admet-1437	719	19	z.k	z.k	PROPN
admet-1437	719	20	.	.	PROPN
admet-1437	719	21	nagy	nagy	PROPN
admet-1437	719	22	,	,	PUNCT
admet-1437	719	23	d.	d.	PROPN
admet-1437	719	24	ramkrishna	ramkrishna	PROPN
admet-1437	719	25	.	.	PUNCT
admet-1437	720	1	nanocrystal	nanocrystal	ADJ
admet-1437	720	2	dissolution	dissolution	PROPN
admet-1437	720	3	kinetics	kinetic	NOUN
admet-1437	720	4	and	and	CCONJ
admet-1437	720	5	solubility	solubility	NOUN
admet-1437	720	6	increase	increase	NOUN
admet-1437	720	7	prediction	prediction	NOUN
admet-1437	720	8	from	from	ADP
admet-1437	720	9	molecular	molecular	ADJ
admet-1437	720	10	dynamics	dynamic	NOUN
admet-1437	720	11	:	:	PUNCT
admet-1437	720	12	the	the	DET
admet-1437	720	13	case	case	NOUN
admet-1437	720	14	of	of	ADP
admet-1437	720	15	α‑	α‑	NUM
admet-1437	720	16	,	,	PUNCT
admet-1437	720	17	β‑	β‑	NUM
admet-1437	720	18	,	,	PUNCT
admet-1437	720	19	and	and	CCONJ
admet-1437	720	20	γ‑glycine	γ‑glycine	NOUN
admet-1437	720	21	.	.	PUNCT
admet-1437	721	1	molecular	molecular	ADJ
admet-1437	721	2	pharmaceutics	pharmaceutic	NOUN
admet-1437	721	3	14	14	NUM
admet-1437	721	4	(	(	PUNCT
admet-1437	721	5	2017	2017	NUM
admet-1437	721	6	)	)	PUNCT
admet-1437	721	7	1023	1023	NUM
admet-1437	721	8	-	-	SYM
admet-1437	721	9	1032	1032	NUM
admet-1437	721	10	.	.	PUNCT
admet-1437	722	1	https://doi.org/10.1021/acs.molpharmaceut.6b00882	https://doi.org/10.1021/acs.molpharmaceut.6b00882	X
admet-1437	722	2	.	.	PUNCT
admet-1437	723	1	[	[	X
admet-1437	723	2	56	56	NUM
admet-1437	723	3	]	]	X
admet-1437	723	4	d.k	d.k	PROPN
admet-1437	723	5	.	.	PROPN
admet-1437	723	6	owens	owens	PROPN
admet-1437	723	7	,	,	PUNCT
admet-1437	723	8	r.c	r.c	PROPN
admet-1437	723	9	.	.	PROPN
admet-1437	723	10	wendt	wendt	PROPN
admet-1437	723	11	.	.	PUNCT
admet-1437	724	1	estimation	estimation	NOUN
admet-1437	724	2	of	of	ADP
admet-1437	724	3	the	the	DET
admet-1437	724	4	surface	surface	NOUN
admet-1437	724	5	free	free	ADJ
admet-1437	724	6	energy	energy	NOUN
admet-1437	724	7	of	of	ADP
admet-1437	724	8	polymers	polymer	NOUN
admet-1437	724	9	.	.	PUNCT
admet-1437	725	1	journal	journal	NOUN
admet-1437	725	2	of	of	ADP
admet-1437	725	3	applied	apply	VERB
admet-1437	725	4	polymer	polymer	NOUN
admet-1437	725	5	science	science	NOUN
admet-1437	725	6	13	13	NUM
admet-1437	725	7	(	(	PUNCT
admet-1437	725	8	1969	1969	NUM
admet-1437	725	9	)	)	PUNCT
admet-1437	725	10	1741	1741	NUM
admet-1437	725	11	-	-	SYM
admet-1437	725	12	1747	1747	NUM
admet-1437	725	13	.	.	PUNCT
admet-1437	726	1	https://doi.org/10.1002/app.1969.070130815	https://doi.org/10.1002/app.1969.070130815	NOUN
admet-1437	726	2	.	.	PUNCT
admet-1437	727	1	[	[	X
admet-1437	727	2	57	57	NUM
admet-1437	727	3	]	]	X
admet-1437	727	4	d.h	d.h	PROPN
admet-1437	727	5	.	.	PROPN
admet-1437	727	6	kaelble	kaelble	PROPN
admet-1437	727	7	.	.	PUNCT
admet-1437	728	1	dispersion	dispersion	NOUN
admet-1437	728	2	-	-	PUNCT
admet-1437	728	3	polar	polar	ADJ
admet-1437	728	4	surface	surface	NOUN
admet-1437	728	5	tension	tension	NOUN
admet-1437	728	6	properties	property	NOUN
admet-1437	728	7	of	of	ADP
admet-1437	728	8	organic	organic	ADJ
admet-1437	728	9	solids	solid	NOUN
admet-1437	728	10	.	.	PUNCT
admet-1437	729	1	the	the	DET
admet-1437	729	2	journal	journal	NOUN
admet-1437	729	3	of	of	ADP
admet-1437	729	4	adhesion	adhesion	NOUN
admet-1437	729	5	66	66	NUM
admet-1437	729	6	(	(	PUNCT
admet-1437	729	7	1970	1970	NUM
admet-1437	729	8	)	)	PUNCT
admet-1437	729	9	66	66	NUM
admet-1437	729	10	-	-	SYM
admet-1437	729	11	81	81	NUM
admet-1437	729	12	.	.	PUNCT
admet-1437	730	1	https://doi.org/10.1080/0021846708544582	https://doi.org/10.1080/0021846708544582	NUM
admet-1437	730	2	.	.	PUNCT
admet-1437	731	1	[	[	X
admet-1437	731	2	58	58	NUM
admet-1437	731	3	]	]	X
admet-1437	731	4	g.m	g.m	PROPN
admet-1437	731	5	.	.	PROPN
admet-1437	731	6	dorris	dorris	PROPN
admet-1437	731	7	,	,	PUNCT
admet-1437	731	8	d.g	d.g	PROPN
admet-1437	731	9	.	.	PROPN
admet-1437	731	10	gray	gray	ADJ
admet-1437	731	11	.	.	PUNCT
admet-1437	732	1	adsorption	adsorption	NOUN
admet-1437	732	2	of	of	ADP
admet-1437	732	3	n	n	CCONJ
admet-1437	732	4	-	-	PUNCT
admet-1437	732	5	alkanes	alkane	NOUN
admet-1437	732	6	at	at	ADP
admet-1437	732	7	zero	zero	NUM
admet-1437	732	8	surface	surface	NOUN
admet-1437	732	9	coverage	coverage	NOUN
admet-1437	732	10	on	on	ADP
admet-1437	732	11	cellulose	cellulose	NOUN
admet-1437	732	12	paper	paper	NOUN
admet-1437	732	13	and	and	CCONJ
admet-1437	732	14	wood	wood	NOUN
admet-1437	732	15	fibers	fiber	NOUN
admet-1437	732	16	.	.	PUNCT
admet-1437	733	1	journal	journal	PROPN
admet-1437	733	2	of	of	ADP
admet-1437	733	3	colloid	colloid	NOUN
admet-1437	733	4	and	and	CCONJ
admet-1437	733	5	interface	interface	NOUN
admet-1437	733	6	science	science	NOUN
admet-1437	733	7	77	77	NUM
admet-1437	733	8	(	(	PUNCT
admet-1437	733	9	1980	1980	NUM
admet-1437	733	10	)	)	PUNCT
admet-1437	733	11	353	353	NUM
admet-1437	733	12	-	-	SYM
admet-1437	733	13	362	362	NUM
admet-1437	733	14	.	.	PUNCT
admet-1437	734	1	https://doi.org/10.1016/00219797(80)90304-5	https://doi.org/10.1016/00219797(80)90304-5	NOUN
admet-1437	734	2	.	.	PUNCT
admet-1437	735	1	[	[	X
admet-1437	735	2	59	59	NUM
admet-1437	735	3	]	]	SYM
admet-1437	735	4	iso	iso	NOUN
admet-1437	735	5	13320:2020	13320:2020	NUM
admet-1437	735	6	:	:	PUNCT
admet-1437	735	7	particle	particle	NOUN
admet-1437	735	8	size	size	NOUN
admet-1437	735	9	analysis	analysis	NOUN
admet-1437	735	10	–	–	PUNCT
admet-1437	735	11	laser	laser	NOUN
admet-1437	735	12	diffraction	diffraction	NOUN
admet-1437	735	13	methods	method	NOUN
admet-1437	735	14	(	(	PUNCT
admet-1437	735	15	2020	2020	NUM
admet-1437	735	16	)	)	PUNCT
admet-1437	735	17	.	.	PUNCT
admet-1437	736	1	[	[	X
admet-1437	736	2	60	60	NUM
admet-1437	736	3	]	]	X
admet-1437	736	4	iso	iso	NOUN
admet-1437	736	5	22412:2008	22412:2008	NOUN
admet-1437	736	6	:	:	PUNCT
admet-1437	736	7	particle	particle	NOUN
admet-1437	736	8	size	size	NOUN
admet-1437	736	9	analysis	analysis	NOUN
admet-1437	736	10	–	–	PUNCT
admet-1437	736	11	dynamic	dynamic	ADJ
admet-1437	736	12	light	light	NOUN
admet-1437	736	13	scattering	scattering	NOUN
admet-1437	736	14	(	(	PUNCT
admet-1437	736	15	dls	dls	PROPN
admet-1437	736	16	)	)	PUNCT
admet-1437	736	17	(	(	PUNCT
admet-1437	736	18	2008	2008	NUM
admet-1437	736	19	)	)	PUNCT
admet-1437	736	20	.	.	PUNCT
admet-1437	737	1	[	[	X
admet-1437	737	2	61	61	NUM
admet-1437	737	3	]	]	X
admet-1437	737	4	iso	iso	NOUN
admet-1437	737	5	489:2022	489:2022	PROPN
admet-1437	737	6	:	:	PUNCT
admet-1437	737	7	plastics	plastic	NOUN
admet-1437	737	8	–	–	PUNCT
admet-1437	737	9	determination	determination	NOUN
admet-1437	737	10	of	of	ADP
admet-1437	737	11	refractive	refractive	ADJ
admet-1437	737	12	index	index	NOUN
admet-1437	737	13	(	(	PUNCT
admet-1437	737	14	2022	2022	NUM
admet-1437	737	15	)	)	PUNCT
admet-1437	737	16	.	.	PUNCT
admet-1437	738	1	[	[	X
admet-1437	738	2	62	62	NUM
admet-1437	738	3	]	]	SYM
admet-1437	738	4	a.a	a.a	PROPN
admet-1437	738	5	.	.	PROPN
admet-1437	738	6	noyes	noyes	PROPN
admet-1437	738	7	,	,	PUNCT
admet-1437	738	8	w.r	w.r	PROPN
admet-1437	738	9	.	.	PROPN
admet-1437	738	10	whitney	whitney	PROPN
admet-1437	738	11	,	,	PUNCT
admet-1437	738	12	the	the	DET
admet-1437	738	13	rate	rate	NOUN
admet-1437	738	14	of	of	ADP
admet-1437	738	15	solution	solution	NOUN
admet-1437	738	16	of	of	ADP
admet-1437	738	17	solid	solid	ADJ
admet-1437	738	18	substances	substance	NOUN
admet-1437	738	19	in	in	ADP
admet-1437	738	20	their	their	PRON
admet-1437	738	21	own	own	ADJ
admet-1437	738	22	solutions	solution	NOUN
admet-1437	738	23	.	.	PUNCT
admet-1437	739	1	journal	journal	NOUN
admet-1437	739	2	of	of	ADP
admet-1437	739	3	the	the	DET
admet-1437	739	4	american	american	PROPN
admet-1437	739	5	chemical	chemical	PROPN
admet-1437	739	6	society	society	PROPN
admet-1437	739	7	19	19	NUM
admet-1437	739	8	(	(	PUNCT
admet-1437	739	9	1897	1897	NUM
admet-1437	739	10	)	)	PUNCT
admet-1437	739	11	930	930	NUM
admet-1437	739	12	-	-	SYM
admet-1437	739	13	934	934	NUM
admet-1437	739	14	.	.	PUNCT
admet-1437	740	1	https://doi.org/10.1021/ja02086a003	https://doi.org/10.1021/ja02086a003	NOUN
admet-1437	740	2	.	.	PUNCT
admet-1437	741	1	[	[	X
admet-1437	741	2	63	63	NUM
admet-1437	741	3	]	]	PUNCT
admet-1437	741	4	w.	w.	PROPN
admet-1437	741	5	nernst	nernst	PROPN
admet-1437	741	6	.	.	PUNCT
admet-1437	742	1	theorie	theorie	PROPN
admet-1437	742	2	der	der	PROPN
admet-1437	742	3	reaktionsgeschwindigkeit	reaktionsgeschwindigkeit	VERB
admet-1437	742	4	in	in	ADP
admet-1437	742	5	heterogenen	heterogenen	PROPN
admet-1437	742	6	systemen	systemen	NOUN
admet-1437	742	7	.	.	PUNCT
admet-1437	743	1	zeitschrift	zeitschrift	PROPN
admet-1437	743	2	für	für	PROPN
admet-1437	743	3	physikalische	physikalische	PROPN
admet-1437	743	4	chemie	chemie	PROPN
admet-1437	743	5	47	47	NUM
admet-1437	743	6	(	(	PUNCT
admet-1437	743	7	1904	1904	NUM
admet-1437	743	8	)	)	PUNCT
admet-1437	743	9	52	52	NUM
admet-1437	743	10	-	-	SYM
admet-1437	743	11	55	55	NUM
admet-1437	743	12	.	.	PUNCT
admet-1437	744	1	https://doi.org/10.1515/zpch-1904-4704	https://doi.org/10.1515/zpch-1904-4704	VERB
admet-1437	744	2	.	.	PUNCT
admet-1437	745	1	[	[	X
admet-1437	745	2	64	64	NUM
admet-1437	745	3	]	]	PUNCT
admet-1437	745	4	l.	l.	PROPN
admet-1437	745	5	prandtl	prandtl	PROPN
admet-1437	745	6	.	.	PUNCT
admet-1437	746	1	verhandlungen	verhandlungen	PROPN
admet-1437	746	2	des	des	PROPN
admet-1437	746	3	dritten	dritten	PROPN
admet-1437	746	4	internationalen	internationalen	ADJ
admet-1437	746	5	mathematiker	mathematiker	NOUN
admet-1437	746	6	-	-	PUNCT
admet-1437	746	7	kongresses	kongresse	NOUN
admet-1437	746	8	in	in	ADP
admet-1437	746	9	heidelberg	heidelberg	PROPN
admet-1437	746	10	1904	1904	NUM
admet-1437	746	11	vom	vom	VERB
admet-1437	746	12	8	8	NUM
admet-1437	746	13	.	.	PUNCT
admet-1437	746	14	bis	bis	PROPN
admet-1437	746	15	14	14	NUM
admet-1437	746	16	.	.	PUNCT
admet-1437	747	1	august	august	PROPN
admet-1437	747	2	1904	1904	NUM
admet-1437	747	3	.	.	PUNCT
admet-1437	748	1	b.g	b.g	PROPN
admet-1437	748	2	.	.	PROPN
admet-1437	748	3	teubner	teubner	NOUN
admet-1437	748	4	,	,	PUNCT
admet-1437	748	5	leipzig	leipzig	PROPN
admet-1437	748	6	,	,	PUNCT
admet-1437	748	7	germany	germany	PROPN
admet-1437	748	8	,	,	PUNCT
admet-1437	748	9	1905	1905	NUM
admet-1437	748	10	,	,	PUNCT
admet-1437	748	11	p.	p.	NOUN
admet-1437	748	12	484	484	NUM
admet-1437	748	13	.	.	PUNCT
admet-1437	749	1	[	[	X
admet-1437	749	2	65	65	NUM
admet-1437	749	3	]	]	X
admet-1437	749	4	m.	m.	NOUN
admet-1437	749	5	bisrat	bisrat	NOUN
admet-1437	749	6	,	,	PUNCT
admet-1437	749	7	c.	c.	PROPN
admet-1437	749	8	nyström	nyström	PROPN
admet-1437	749	9	.	.	PUNCT
admet-1437	750	1	physicochemical	physicochemical	ADJ
admet-1437	750	2	aspects	aspect	NOUN
admet-1437	750	3	of	of	ADP
admet-1437	750	4	drug	drug	NOUN
admet-1437	750	5	release	release	NOUN
admet-1437	750	6	.	.	PUNCT
admet-1437	751	1	viii	viii	PROPN
admet-1437	751	2	.	.	PUNCT
admet-1437	752	1	the	the	DET
admet-1437	752	2	relation	relation	NOUN
admet-1437	752	3	between	between	ADP
admet-1437	752	4	particle	particle	NOUN
admet-1437	752	5	size	size	NOUN
admet-1437	752	6	and	and	CCONJ
admet-1437	752	7	surface	surface	NOUN
admet-1437	752	8	specific	specific	ADJ
admet-1437	752	9	dissolution	dissolution	NOUN
admet-1437	752	10	rate	rate	NOUN
admet-1437	752	11	in	in	ADP
admet-1437	752	12	agitated	agitated	ADJ
admet-1437	752	13	suspensions	suspension	NOUN
admet-1437	752	14	.	.	PUNCT
admet-1437	753	1	international	international	ADJ
admet-1437	753	2	journal	journal	PROPN
admet-1437	753	3	of	of	ADP
admet-1437	753	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	753	5	47	47	NUM
admet-1437	753	6	(	(	PUNCT
admet-1437	753	7	1988	1988	NUM
admet-1437	753	8	)	)	PUNCT
admet-1437	753	9	223	223	NUM
admet-1437	753	10	-	-	SYM
admet-1437	753	11	231	231	NUM
admet-1437	753	12	.	.	PUNCT
admet-1437	754	1	https://doi.org/10.1016/0378-5173(88)90235-9	https://doi.org/10.1016/0378-5173(88)90235-9	NOUN
admet-1437	754	2	.	.	PUNCT
admet-1437	755	1	[	[	X
admet-1437	755	2	66	66	NUM
admet-1437	755	3	]	]	X
admet-1437	755	4	p.j	p.j	PROPN
admet-1437	755	5	.	.	PROPN
admet-1437	755	6	niebergall	niebergall	PROPN
admet-1437	755	7	,	,	PUNCT
admet-1437	755	8	g.	g.	PROPN
admet-1437	755	9	milosovich	milosovich	PROPN
admet-1437	755	10	,	,	PUNCT
admet-1437	755	11	j.e	j.e	PROPN
admet-1437	755	12	.	.	PROPN
admet-1437	755	13	goyan	goyan	PROPN
admet-1437	755	14	.	.	PUNCT
admet-1437	756	1	dissolution	dissolution	PROPN
admet-1437	756	2	rate	rate	NOUN
admet-1437	756	3	studies	study	NOUN
admet-1437	756	4	.	.	PUNCT
admet-1437	757	1	ii	ii	PROPN
admet-1437	757	2	.	.	PUNCT
admet-1437	758	1	dissolution	dissolution	NOUN
admet-1437	758	2	of	of	ADP
admet-1437	758	3	particles	particle	NOUN
admet-1437	758	4	under	under	ADP
admet-1437	758	5	conditions	condition	NOUN
admet-1437	758	6	of	of	ADP
admet-1437	758	7	rapid	rapid	ADJ
admet-1437	758	8	agitation	agitation	NOUN
admet-1437	758	9	.	.	PUNCT
admet-1437	759	1	journal	journal	NOUN
admet-1437	759	2	of	of	ADP
admet-1437	759	3	pharmaceutical	pharmaceutical	ADJ
admet-1437	759	4	sciences	science	NOUN
admet-1437	759	5	52	52	NUM
admet-1437	759	6	(	(	PUNCT
admet-1437	759	7	1963	1963	NUM
admet-1437	759	8	)	)	PUNCT
admet-1437	759	9	236	236	NUM
admet-1437	759	10	-	-	SYM
admet-1437	759	11	241	241	NUM
admet-1437	759	12	.	.	PUNCT
admet-1437	760	1	https://doi.org/10.1002/jps.2600520310	https://doi.org/10.1002/jps.2600520310	PROPN
admet-1437	760	2	.	.	PUNCT
admet-1437	761	1	[	[	X
admet-1437	761	2	67	67	NUM
admet-1437	761	3	]	]	X
admet-1437	761	4	w.i	w.i	PROPN
admet-1437	761	5	.	.	PROPN
admet-1437	761	6	higuchi	higuchi	PROPN
admet-1437	761	7	,	,	PUNCT
admet-1437	761	8	e.n	e.n	PROPN
admet-1437	761	9	.	.	PROPN
admet-1437	761	10	hiestand	hiestand	PROPN
admet-1437	761	11	.	.	PUNCT
admet-1437	762	1	dissolution	dissolution	NOUN
admet-1437	762	2	rates	rate	NOUN
admet-1437	762	3	of	of	ADP
admet-1437	762	4	finely	finely	ADV
admet-1437	762	5	divided	divide	VERB
admet-1437	762	6	drug	drug	NOUN
admet-1437	762	7	powders	powder	NOUN
admet-1437	762	8	.	.	PUNCT
admet-1437	763	1	i.	i.	PROPN
admet-1437	763	2	effect	effect	NOUN
admet-1437	763	3	of	of	ADP
admet-1437	763	4	a	a	DET
admet-1437	763	5	distribution	distribution	NOUN
admet-1437	763	6	of	of	ADP
admet-1437	763	7	particle	particle	NOUN
admet-1437	763	8	sizes	size	NOUN
admet-1437	763	9	in	in	ADP
admet-1437	763	10	a	a	DET
admet-1437	763	11	diffusion	diffusion	NOUN
admet-1437	763	12	-	-	PUNCT
admet-1437	763	13	controlled	control	VERB
admet-1437	763	14	process	process	NOUN
admet-1437	763	15	.	.	PUNCT
admet-1437	764	1	journal	journal	NOUN
admet-1437	764	2	of	of	ADP
admet-1437	764	3	pharmaceutical	pharmaceutical	ADJ
admet-1437	764	4	sciences	science	NOUN
admet-1437	764	5	52	52	NUM
admet-1437	764	6	(	(	PUNCT
admet-1437	764	7	1963	1963	NUM
admet-1437	764	8	)	)	PUNCT
admet-1437	764	9	67	67	NUM
admet-1437	764	10	-	-	SYM
admet-1437	764	11	71	71	NUM
admet-1437	764	12	.	.	PUNCT
admet-1437	765	1	https://doi.org/10.1002/jps.2600520114	https://doi.org/10.1002/jps.2600520114	NOUN
admet-1437	765	2	.	.	PUNCT
admet-1437	766	1	[	[	X
admet-1437	766	2	68	68	NUM
admet-1437	766	3	]	]	X
admet-1437	766	4	r.j	r.j	PROPN
admet-1437	766	5	.	.	PROPN
admet-1437	766	6	hintz	hintz	PROPN
admet-1437	766	7	,	,	PUNCT
admet-1437	766	8	k.c	k.c	PROPN
admet-1437	766	9	.	.	PROPN
admet-1437	766	10	johnson	johnson	PROPN
admet-1437	766	11	.	.	PUNCT
admet-1437	767	1	the	the	DET
admet-1437	767	2	effect	effect	NOUN
admet-1437	767	3	of	of	ADP
admet-1437	767	4	particle	particle	NOUN
admet-1437	767	5	size	size	NOUN
admet-1437	767	6	distribution	distribution	NOUN
admet-1437	767	7	on	on	ADP
admet-1437	767	8	dissolution	dissolution	ADJ
admet-1437	767	9	rate	rate	NOUN
admet-1437	767	10	and	and	CCONJ
admet-1437	767	11	oral	oral	ADJ
admet-1437	767	12	absorption	absorption	NOUN
admet-1437	767	13	.	.	PUNCT
admet-1437	768	1	international	international	ADJ
admet-1437	768	2	journal	journal	PROPN
admet-1437	768	3	of	of	ADP
admet-1437	768	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	768	5	51	51	NUM
admet-1437	768	6	(	(	PUNCT
admet-1437	768	7	1989	1989	NUM
admet-1437	768	8	)	)	PUNCT
admet-1437	768	9	9	9	NUM
admet-1437	768	10	-	-	SYM
admet-1437	768	11	17	17	NUM
admet-1437	768	12	.	.	PUNCT
admet-1437	769	1	https://doi.org/10.1016/0378-5173(89)900690	https://doi.org/10.1016/0378-5173(89)900690	ADJ
admet-1437	769	2	.	.	PUNCT
admet-1437	770	1	[	[	X
admet-1437	770	2	69	69	NUM
admet-1437	770	3	]	]	X
admet-1437	770	4	c.	c.	NOUN
admet-1437	770	5	galli	galli	NOUN
admet-1437	770	6	.	.	PUNCT
admet-1437	771	1	experimental	experimental	ADJ
admet-1437	771	2	determination	determination	NOUN
admet-1437	771	3	of	of	ADP
admet-1437	771	4	the	the	DET
admet-1437	771	5	diffusion	diffusion	NOUN
admet-1437	771	6	boundary	boundary	ADJ
admet-1437	771	7	layer	layer	NOUN
admet-1437	771	8	width	width	NOUN
admet-1437	771	9	of	of	ADP
admet-1437	771	10	micron	micron	NOUN
admet-1437	771	11	and	and	CCONJ
admet-1437	771	12	submicron	submicron	NOUN
admet-1437	771	13	particles	particle	NOUN
admet-1437	771	14	.	.	PUNCT
admet-1437	772	1	international	international	ADJ
admet-1437	772	2	journal	journal	PROPN
admet-1437	772	3	of	of	ADP
admet-1437	772	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	772	5	313	313	NUM
admet-1437	772	6	(	(	PUNCT
admet-1437	772	7	2006	2006	NUM
admet-1437	772	8	)	)	PUNCT
admet-1437	772	9	114	114	NUM
admet-1437	772	10	-	-	SYM
admet-1437	772	11	122	122	NUM
admet-1437	772	12	.	.	PUNCT
admet-1437	773	1	https://doi.org/10.1016/j.ijpharm.2006.01.030	https://doi.org/10.1016/j.ijpharm.2006.01.030	NOUN
admet-1437	773	2	.	.	PUNCT
admet-1437	774	1	[	[	X
admet-1437	774	2	70	70	NUM
admet-1437	774	3	]	]	PUNCT
admet-1437	774	4	k.	k.	PROPN
admet-1437	774	5	sugano	sugano	PROPN
admet-1437	774	6	.	.	PUNCT
admet-1437	775	1	theoretical	theoretical	ADJ
admet-1437	775	2	comparison	comparison	NOUN
admet-1437	775	3	of	of	ADP
admet-1437	775	4	hydrodynamic	hydrodynamic	ADJ
admet-1437	775	5	diffusion	diffusion	NOUN
admet-1437	775	6	layer	layer	NOUN
admet-1437	775	7	models	model	NOUN
admet-1437	775	8	used	use	VERB
admet-1437	775	9	for	for	ADP
admet-1437	775	10	dissolution	dissolution	ADJ
admet-1437	775	11	simulation	simulation	NOUN
admet-1437	775	12	in	in	ADP
admet-1437	775	13	drug	drug	NOUN
admet-1437	775	14	discovery	discovery	NOUN
admet-1437	775	15	and	and	CCONJ
admet-1437	775	16	development	development	NOUN
admet-1437	775	17	.	.	PUNCT
admet-1437	776	1	international	international	ADJ
admet-1437	776	2	journal	journal	PROPN
admet-1437	776	3	of	of	ADP
admet-1437	776	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	776	5	363	363	NUM
admet-1437	776	6	(	(	PUNCT
admet-1437	776	7	2008	2008	NUM
admet-1437	776	8	)	)	PUNCT
admet-1437	776	9	7377	7377	NUM
admet-1437	776	10	.	.	PUNCT
admet-1437	777	1	https://doi.org/10.1016/j.ijpharm.2008.07.002	https://doi.org/10.1016/j.ijpharm.2008.07.002	NOUN
admet-1437	777	2	.	.	PUNCT
admet-1437	778	1	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	X
admet-1437	778	2	http://dx.doi.org/10.5599/admet.841	http://dx.doi.org/10.5599/admet.841	X
admet-1437	778	3	http://dx.doi.org/10.5599/admet.841	http://dx.doi.org/10.5599/admet.841	X
admet-1437	778	4	https://doi.org/10.1021/acsomega.0c05558	https://doi.org/10.1021/acsomega.0c05558	PROPN
admet-1437	778	5	https://doi.org/10.1016/j.powtec.2014.01.095	https://doi.org/10.1016/j.powtec.2014.01.095	PROPN
admet-1437	778	6	https://doi.org/10.1016/j.powtec.2014.01.095	https://doi.org/10.1016/j.powtec.2014.01.095	PROPN
admet-1437	778	7	https://doi.org/10.1002/jps.22778	https://doi.org/10.1002/jps.22778	PROPN
admet-1437	778	8	https://doi.org/10.1002/jps.22778	https://doi.org/10.1002/jps.22778	PROPN
admet-1437	778	9	https://doi.org/10.1021/acs.molpharmaceut.6b00882	https://doi.org/10.1021/acs.molpharmaceut.6b00882	NOUN
admet-1437	778	10	https://doi.org/10.1021/acs.molpharmaceut.6b00882	https://doi.org/10.1021/acs.molpharmaceut.6b00882	NOUN
admet-1437	778	11	https://doi.org/10.1002/app.1969.070130815	https://doi.org/10.1002/app.1969.070130815	NOUN
admet-1437	778	12	https://doi.org/10.1080/0021846708544582	https://doi.org/10.1080/0021846708544582	NUM
admet-1437	778	13	https://doi.org/10.1016/00219797(80)90304-5	https://doi.org/10.1016/00219797(80)90304-5	NOUN
admet-1437	778	14	https://doi.org/10.1016/00219797(80)90304-5	https://doi.org/10.1016/00219797(80)90304-5	NOUN
admet-1437	778	15	https://doi.org/10.1021/ja02086a003	https://doi.org/10.1021/ja02086a003	PROPN
admet-1437	778	16	https://doi.org/10.1515/zpch-1904-4704	https://doi.org/10.1515/zpch-1904-4704	VERB
admet-1437	778	17	https://doi.org/10.1016/0378-5173(88)90235-9	https://doi.org/10.1016/0378-5173(88)90235-9	PROPN
admet-1437	778	18	https://doi.org/10.1002/jps.2600520310	https://doi.org/10.1002/jps.2600520310	PROPN
admet-1437	778	19	https://doi.org/10.1002/jps.2600520310	https://doi.org/10.1002/jps.2600520310	PROPN
admet-1437	778	20	https://doi.org/10.1002/jps.2600520114	https://doi.org/10.1002/jps.2600520114	PROPN
admet-1437	778	21	https://doi.org/10.1016/0378-5173(89)90069-0	https://doi.org/10.1016/0378-5173(89)90069-0	PROPN
admet-1437	778	22	https://doi.org/10.1016/0378-5173(89)90069-0	https://doi.org/10.1016/0378-5173(89)90069-0	PROPN
admet-1437	778	23	https://doi.org/10.1016/j.ijpharm.2006.01.030	https://doi.org/10.1016/j.ijpharm.2006.01.030	PROPN
admet-1437	778	24	https://doi.org/10.1016/j.ijpharm.2006.01.030	https://doi.org/10.1016/j.ijpharm.2006.01.030	PROPN
admet-1437	778	25	https://doi.org/10.1016/j.ijpharm.2008.07.002	https://doi.org/10.1016/j.ijpharm.2008.07.002	PROPN
admet-1437	778	26	bonhoeffer	bonhoeffer	PROPN
admet-1437	778	27	et	et	PROPN
admet-1437	778	28	al	al	PROPN
admet-1437	778	29	.	.	PROPN
admet-1437	778	30	admet	admet	PROPN
admet-1437	778	31	&	&	CCONJ
admet-1437	778	32	dmpk	dmpk	PROPN
admet-1437	778	33	10(4	10(4	NUM
admet-1437	778	34	)	)	PUNCT
admet-1437	778	35	(	(	PUNCT
admet-1437	778	36	2022	2022	NUM
admet-1437	778	37	)	)	PUNCT
admet-1437	779	1	253	253	NUM
admet-1437	779	2	-	-	SYM
admet-1437	779	3	287	287	NUM
admet-1437	779	4	286	286	NUM
admet-1437	779	5	[	[	X
admet-1437	779	6	71	71	NUM
admet-1437	779	7	]	]	X
admet-1437	779	8	l.	l.	PROPN
admet-1437	779	9	lindfors	lindfors	PROPN
admet-1437	779	10	,	,	PUNCT
admet-1437	779	11	m.	m.	PROPN
admet-1437	779	12	jonsson	jonsson	PROPN
admet-1437	779	13	,	,	PUNCT
admet-1437	779	14	e.	e.	PROPN
admet-1437	779	15	weibull	weibull	PROPN
admet-1437	779	16	,	,	PUNCT
admet-1437	779	17	j.g	j.g	PROPN
admet-1437	779	18	.	.	PROPN
admet-1437	779	19	brasseur	brasseur	PROPN
admet-1437	779	20	,	,	PUNCT
admet-1437	779	21	b.	b.	PROPN
admet-1437	779	22	abrahamson	abrahamson	PROPN
admet-1437	779	23	.	.	PUNCT
admet-1437	780	1	hydrodynamic	hydrodynamic	ADJ
admet-1437	780	2	effects	effect	NOUN
admet-1437	780	3	on	on	ADP
admet-1437	780	4	drug	drug	NOUN
admet-1437	780	5	dissolution	dissolution	NOUN
admet-1437	780	6	and	and	CCONJ
admet-1437	780	7	deaggregation	deaggregation	NOUN
admet-1437	780	8	in	in	ADP
admet-1437	780	9	the	the	DET
admet-1437	780	10	small	small	ADJ
admet-1437	780	11	intestine	intestine	NOUN
admet-1437	780	12	–	–	PUNCT
admet-1437	780	13	a	a	DET
admet-1437	780	14	study	study	NOUN
admet-1437	780	15	with	with	ADP
admet-1437	780	16	felodipine	felodipine	NOUN
admet-1437	780	17	as	as	ADP
admet-1437	780	18	a	a	DET
admet-1437	780	19	model	model	NOUN
admet-1437	780	20	drug	drug	NOUN
admet-1437	780	21	.	.	PUNCT
admet-1437	781	1	journal	journal	PROPN
admet-1437	781	2	of	of	ADP
admet-1437	781	3	pharmaceutical	pharmaceutical	PROPN
admet-1437	781	4	sciences	science	NOUN
admet-1437	781	5	104	104	NUM
admet-1437	781	6	(	(	PUNCT
admet-1437	781	7	2015	2015	NUM
admet-1437	781	8	)	)	PUNCT
admet-1437	781	9	2969	2969	NUM
admet-1437	781	10	-	-	SYM
admet-1437	781	11	2976	2976	NUM
admet-1437	781	12	.	.	PUNCT
admet-1437	782	1	https://doi.org/10.1002/jps.24487	https://doi.org/10.1002/jps.24487	PROPN
admet-1437	782	2	.	.	PUNCT
admet-1437	783	1	[	[	X
admet-1437	783	2	72	72	NUM
admet-1437	783	3	]	]	X
admet-1437	783	4	l.f	l.f	PROPN
admet-1437	783	5	.	.	PROPN
admet-1437	783	6	knapp	knapp	PROPN
admet-1437	783	7	.	.	PUNCT
admet-1437	784	1	the	the	DET
admet-1437	784	2	solubility	solubility	NOUN
admet-1437	784	3	of	of	ADP
admet-1437	784	4	small	small	ADJ
admet-1437	784	5	particles	particle	NOUN
admet-1437	784	6	and	and	CCONJ
admet-1437	784	7	the	the	DET
admet-1437	784	8	stability	stability	NOUN
admet-1437	784	9	of	of	ADP
admet-1437	784	10	colloids	colloid	NOUN
admet-1437	784	11	.	.	PUNCT
admet-1437	785	1	transactions	transaction	NOUN
admet-1437	785	2	of	of	ADP
admet-1437	785	3	the	the	DET
admet-1437	785	4	faraday	faraday	PROPN
admet-1437	785	5	society	society	PROPN
admet-1437	785	6	17	17	NUM
admet-1437	785	7	(	(	PUNCT
admet-1437	785	8	1922	1922	NUM
admet-1437	785	9	)	)	PUNCT
admet-1437	785	10	457	457	NUM
admet-1437	785	11	-	-	SYM
admet-1437	785	12	465	465	NUM
admet-1437	785	13	.	.	PUNCT
admet-1437	786	1	https://doi.org/10.1039/tf9221700457	https://doi.org/10.1039/tf9221700457	X
admet-1437	786	2	.	.	PUNCT
admet-1437	787	1	[	[	X
admet-1437	787	2	73	73	NUM
admet-1437	787	3	]	]	X
admet-1437	787	4	d.m	d.m	X
admet-1437	787	5	.	.	PUNCT
admet-1437	788	1	oh	oh	INTJ
admet-1437	788	2	,	,	PUNCT
admet-1437	788	3	r.l	r.l	PROPN
admet-1437	788	4	.	.	PROPN
admet-1437	788	5	curl	curl	PROPN
admet-1437	788	6	,	,	PUNCT
admet-1437	788	7	g.l	g.l	PROPN
admet-1437	788	8	.	.	PROPN
admet-1437	788	9	amidon	amidon	PROPN
admet-1437	788	10	.	.	PUNCT
admet-1437	789	1	estimating	estimate	VERB
admet-1437	789	2	the	the	DET
admet-1437	789	3	fraction	fraction	NOUN
admet-1437	789	4	dose	dose	NOUN
admet-1437	789	5	absorbed	absorb	VERB
admet-1437	789	6	from	from	ADP
admet-1437	789	7	suspensions	suspension	NOUN
admet-1437	789	8	of	of	ADP
admet-1437	789	9	poorly	poorly	ADV
admet-1437	789	10	soluble	soluble	ADJ
admet-1437	789	11	compounds	compound	NOUN
admet-1437	789	12	in	in	ADP
admet-1437	789	13	humans	human	NOUN
admet-1437	789	14	:	:	PUNCT
admet-1437	789	15	a	a	DET
admet-1437	789	16	mathematical	mathematical	ADJ
admet-1437	789	17	model	model	NOUN
admet-1437	789	18	.	.	PUNCT
admet-1437	790	1	pharmaceutical	pharmaceutical	ADJ
admet-1437	790	2	research	research	NOUN
admet-1437	790	3	10	10	NUM
admet-1437	790	4	(	(	PUNCT
admet-1437	790	5	1993	1993	NUM
admet-1437	790	6	)	)	PUNCT
admet-1437	790	7	264	264	NUM
admet-1437	790	8	-	-	SYM
admet-1437	790	9	270	270	NUM
admet-1437	790	10	.	.	PUNCT
admet-1437	791	1	https://doi.org/10.1023/a:1018947113238	https://doi.org/10.1023/a:1018947113238	NOUN
admet-1437	791	2	.	.	PUNCT
admet-1437	792	1	[	[	X
admet-1437	792	2	74	74	NUM
admet-1437	792	3	]	]	X
admet-1437	792	4	l.x	l.x	PROPN
admet-1437	792	5	.	.	PROPN
admet-1437	792	6	yu	yu	PROPN
admet-1437	792	7	,	,	PUNCT
admet-1437	792	8	e.	e.	PROPN
admet-1437	792	9	lipka	lipka	PROPN
admet-1437	792	10	,	,	PUNCT
admet-1437	792	11	j.r	j.r	PROPN
admet-1437	792	12	.	.	PROPN
admet-1437	792	13	crison	crison	PROPN
admet-1437	792	14	,	,	PUNCT
admet-1437	792	15	g.l	g.l	PROPN
admet-1437	792	16	.	.	PROPN
admet-1437	792	17	amidon	amidon	PROPN
admet-1437	792	18	.	.	PUNCT
admet-1437	793	1	transport	transport	NOUN
admet-1437	793	2	approaches	approach	NOUN
admet-1437	793	3	to	to	ADP
admet-1437	793	4	the	the	DET
admet-1437	793	5	biopharmaceutical	biopharmaceutical	ADJ
admet-1437	793	6	design	design	NOUN
admet-1437	793	7	of	of	ADP
admet-1437	793	8	oral	oral	ADJ
admet-1437	793	9	drug	drug	NOUN
admet-1437	793	10	delivery	delivery	NOUN
admet-1437	793	11	systems	system	NOUN
admet-1437	793	12	:	:	PUNCT
admet-1437	793	13	prediction	prediction	NOUN
admet-1437	793	14	of	of	ADP
admet-1437	793	15	intestinal	intestinal	ADJ
admet-1437	793	16	absorption	absorption	NOUN
admet-1437	793	17	.	.	PUNCT
admet-1437	794	1	advanced	advanced	ADJ
admet-1437	794	2	drug	drug	NOUN
admet-1437	794	3	delivery	delivery	NOUN
admet-1437	794	4	reviews	review	NOUN
admet-1437	794	5	19	19	NUM
admet-1437	794	6	(	(	PUNCT
admet-1437	794	7	1996	1996	NUM
admet-1437	794	8	)	)	PUNCT
admet-1437	794	9	359	359	NUM
admet-1437	794	10	-	-	SYM
admet-1437	794	11	376	376	NUM
admet-1437	794	12	.	.	PUNCT
admet-1437	795	1	https://doi.org/10.1016/0169-409x(96)00009-9	https://doi.org/10.1016/0169-409x(96)00009-9	NOUN
admet-1437	795	2	.	.	PUNCT
admet-1437	796	1	[	[	X
admet-1437	796	2	75	75	NUM
admet-1437	796	3	]	]	X
admet-1437	796	4	j.m	j.m	PROPN
admet-1437	796	5	.	.	PROPN
admet-1437	796	6	butler	butler	PROPN
admet-1437	796	7	,	,	PUNCT
admet-1437	796	8	j.b	j.b	PROPN
admet-1437	796	9	.	.	PUNCT
admet-1437	796	10	dressman	dressman	PROPN
admet-1437	796	11	.	.	PUNCT
admet-1437	797	1	the	the	DET
admet-1437	797	2	developability	developability	NOUN
admet-1437	797	3	classification	classification	NOUN
admet-1437	797	4	system	system	NOUN
admet-1437	797	5	:	:	PUNCT
admet-1437	797	6	application	application	NOUN
admet-1437	797	7	of	of	ADP
admet-1437	797	8	biopharmaceutics	biopharmaceutics	NOUN
admet-1437	797	9	concepts	concept	NOUN
admet-1437	797	10	to	to	PART
admet-1437	797	11	formulation	formulation	NOUN
admet-1437	797	12	development	development	NOUN
admet-1437	797	13	.	.	PUNCT
admet-1437	798	1	journal	journal	PROPN
admet-1437	798	2	of	of	ADP
admet-1437	798	3	pharmaceutical	pharmaceutical	PROPN
admet-1437	798	4	sciences	science	NOUN
admet-1437	798	5	99	99	NUM
admet-1437	798	6	(	(	PUNCT
admet-1437	798	7	2010	2010	NUM
admet-1437	798	8	)	)	PUNCT
admet-1437	798	9	4940	4940	NUM
admet-1437	798	10	-	-	SYM
admet-1437	798	11	4954	4954	NUM
admet-1437	798	12	.	.	PUNCT
admet-1437	799	1	https://doi.org/10.1002/jps.22217	https://doi.org/10.1002/jps.22217	NOUN
admet-1437	799	2	.	.	PUNCT
admet-1437	800	1	[	[	X
admet-1437	800	2	76	76	NUM
admet-1437	800	3	]	]	X
admet-1437	800	4	l.z	l.z	PROPN
admet-1437	800	5	.	.	PROPN
admet-1437	800	6	benet	benet	PROPN
admet-1437	800	7	,	,	PUNCT
admet-1437	800	8	f.	f.	PROPN
admet-1437	800	9	broccatelli	broccatelli	PROPN
admet-1437	800	10	,	,	PUNCT
admet-1437	800	11	t.i	t.i	PROPN
admet-1437	800	12	.	.	PROPN
admet-1437	800	13	oprea	oprea	PROPN
admet-1437	800	14	.	.	PUNCT
admet-1437	801	1	bddcs	bddcs	PROPN
admet-1437	801	2	applied	apply	VERB
admet-1437	801	3	to	to	ADP
admet-1437	801	4	over	over	ADP
admet-1437	801	5	900	900	NUM
admet-1437	801	6	drugs	drug	NOUN
admet-1437	801	7	.	.	PUNCT
admet-1437	802	1	the	the	DET
admet-1437	802	2	aaps	aaps	PROPN
admet-1437	802	3	journal	journal	PROPN
admet-1437	802	4	13	13	NUM
admet-1437	802	5	(	(	PUNCT
admet-1437	802	6	2011	2011	NUM
admet-1437	802	7	)	)	PUNCT
admet-1437	802	8	519547	519547	NUM
admet-1437	802	9	.	.	PUNCT
admet-1437	803	1	https://doi.org/10.1208/s12248-011-9290-9	https://doi.org/10.1208/s12248-011-9290-9	X
admet-1437	803	2	.	.	PUNCT
admet-1437	804	1	[	[	X
admet-1437	804	2	77	77	NUM
admet-1437	804	3	]	]	SYM
admet-1437	804	4	w.p	w.p	PROPN
admet-1437	804	5	.	.	PROPN
admet-1437	804	6	wuelfing	wuelfing	PROPN
admet-1437	804	7	,	,	PUNCT
admet-1437	804	8	p.	p.	NOUN
admet-1437	804	9	daublain	daublain	PROPN
admet-1437	804	10	,	,	PUNCT
admet-1437	804	11	f.	f.	PROPN
admet-1437	804	12	kesisoglou	kesisoglou	PROPN
admet-1437	804	13	,	,	PUNCT
admet-1437	804	14	a.	a.	PROPN
admet-1437	804	15	templeton	templeton	PROPN
admet-1437	804	16	,	,	PUNCT
admet-1437	804	17	c.	c.	PROPN
admet-1437	804	18	mcgregor	mcgregor	PROPN
admet-1437	804	19	.	.	PUNCT
admet-1437	805	1	preclinical	preclinical	ADJ
admet-1437	805	2	dose	dose	NOUN
admet-1437	805	3	number	number	NOUN
admet-1437	805	4	and	and	CCONJ
admet-1437	805	5	its	its	PRON
admet-1437	805	6	application	application	NOUN
admet-1437	805	7	in	in	ADP
admet-1437	805	8	understanding	understand	VERB
admet-1437	805	9	drug	drug	NOUN
admet-1437	805	10	absorption	absorption	NOUN
admet-1437	805	11	risk	risk	NOUN
admet-1437	805	12	and	and	CCONJ
admet-1437	805	13	formulation	formulation	NOUN
admet-1437	805	14	design	design	NOUN
admet-1437	805	15	for	for	ADP
admet-1437	805	16	preclinical	preclinical	ADJ
admet-1437	805	17	species	specie	NOUN
admet-1437	805	18	.	.	PUNCT
admet-1437	806	1	molecular	molecular	ADJ
admet-1437	806	2	pharmaceutics	pharmaceutic	NOUN
admet-1437	806	3	12	12	NUM
admet-1437	806	4	(	(	PUNCT
admet-1437	806	5	2015	2015	NUM
admet-1437	806	6	)	)	PUNCT
admet-1437	806	7	1031	1031	NUM
admet-1437	806	8	-	-	SYM
admet-1437	806	9	1039	1039	NUM
admet-1437	806	10	.	.	PUNCT
admet-1437	807	1	https://doi.org/10.1021/mp500504q	https://doi.org/10.1021/mp500504q	NOUN
admet-1437	807	2	.	.	PUNCT
admet-1437	808	1	[	[	X
admet-1437	808	2	78	78	NUM
admet-1437	808	3	]	]	PUNCT
admet-1437	808	4	k.	k.	PROPN
admet-1437	808	5	sugano	sugano	PROPN
admet-1437	808	6	,	,	PUNCT
admet-1437	808	7	k.	k.	PROPN
admet-1437	808	8	terada	terada	PROPN
admet-1437	808	9	.	.	PUNCT
admet-1437	809	1	rateand	rateand	NOUN
admet-1437	809	2	extent	extent	NOUN
admet-1437	809	3	-	-	PUNCT
admet-1437	809	4	limiting	limit	VERB
admet-1437	809	5	factors	factor	NOUN
admet-1437	809	6	of	of	ADP
admet-1437	809	7	oral	oral	ADJ
admet-1437	809	8	drug	drug	NOUN
admet-1437	809	9	absorption	absorption	NOUN
admet-1437	809	10	:	:	PUNCT
admet-1437	809	11	theory	theory	NOUN
admet-1437	809	12	and	and	CCONJ
admet-1437	809	13	applications	application	NOUN
admet-1437	809	14	.	.	PUNCT
admet-1437	810	1	journal	journal	NOUN
admet-1437	810	2	of	of	ADP
admet-1437	810	3	pharmaceutical	pharmaceutical	PROPN
admet-1437	810	4	sciences	science	NOUN
admet-1437	810	5	104	104	NUM
admet-1437	810	6	(	(	PUNCT
admet-1437	810	7	2015	2015	NUM
admet-1437	810	8	)	)	PUNCT
admet-1437	810	9	2777	2777	NUM
admet-1437	810	10	-	-	SYM
admet-1437	810	11	2788	2788	NUM
admet-1437	810	12	.	.	PUNCT
admet-1437	811	1	https://doi.org/10.1002/-jps.24391	https://doi.org/10.1002/-jps.24391	ADJ
admet-1437	811	2	.	.	PUNCT
admet-1437	812	1	[	[	X
admet-1437	812	2	79	79	NUM
admet-1437	812	3	]	]	PUNCT
admet-1437	812	4	j.	j.	PROPN
admet-1437	812	5	rosenberger	rosenberger	PROPN
admet-1437	812	6	,	,	PUNCT
admet-1437	812	7	j.	j.	PROPN
admet-1437	812	8	butler	butler	PROPN
admet-1437	812	9	,	,	PUNCT
admet-1437	812	10	j.	j.	PROPN
admet-1437	812	11	dressman	dressman	PROPN
admet-1437	812	12	.	.	PUNCT
admet-1437	813	1	a	a	DET
admet-1437	813	2	refined	refined	ADJ
admet-1437	813	3	developability	developability	NOUN
admet-1437	813	4	classification	classification	NOUN
admet-1437	813	5	system	system	NOUN
admet-1437	813	6	.	.	PUNCT
admet-1437	814	1	journal	journal	NOUN
admet-1437	814	2	of	of	ADP
admet-1437	814	3	pharmaceutical	pharmaceutical	PROPN
admet-1437	814	4	sciences	science	NOUN
admet-1437	814	5	107	107	NUM
admet-1437	814	6	(	(	PUNCT
admet-1437	814	7	2018	2018	NUM
admet-1437	814	8	)	)	PUNCT
admet-1437	814	9	2020	2020	NUM
admet-1437	814	10	-	-	SYM
admet-1437	814	11	2032	2032	NUM
admet-1437	814	12	.	.	PUNCT
admet-1437	815	1	https://doi.org/10.1016/j.xphs.2018.03.030	https://doi.org/10.1016/j.xphs.2018.03.030	PROPN
admet-1437	815	2	.	.	PUNCT
admet-1437	816	1	[	[	X
admet-1437	816	2	80	80	NUM
admet-1437	816	3	]	]	SYM
admet-1437	816	4	w.p	w.p	PROPN
admet-1437	816	5	.	.	PROPN
admet-1437	816	6	wuelfing	wuelfing	PROPN
admet-1437	816	7	,	,	PUNCT
admet-1437	816	8	a.	a.	PROPN
admet-1437	816	9	el	el	PROPN
admet-1437	816	10	marrouni	marrouni	PROPN
admet-1437	816	11	,	,	PUNCT
admet-1437	816	12	m.p	m.p	PROPN
admet-1437	816	13	.	.	PROPN
admet-1437	816	14	lipert	lipert	PROPN
admet-1437	816	15	,	,	PUNCT
admet-1437	816	16	p.	p.	NOUN
admet-1437	816	17	daublain	daublain	NOUN
admet-1437	816	18	,	,	PUNCT
admet-1437	816	19	f.	f.	PROPN
admet-1437	816	20	kesisoglou	kesisoglou	PROPN
admet-1437	816	21	,	,	PUNCT
admet-1437	816	22	a.	a.	PROPN
admet-1437	816	23	converso	converso	PROPN
admet-1437	816	24	,	,	PUNCT
admet-1437	816	25	a.c	a.c	PROPN
admet-1437	816	26	.	.	PROPN
admet-1437	816	27	templeton	templeton	PROPN
admet-1437	816	28	.	.	PUNCT
admet-1437	817	1	dose	dose	NOUN
admet-1437	817	2	number	number	NOUN
admet-1437	817	3	as	as	ADP
admet-1437	817	4	a	a	DET
admet-1437	817	5	tool	tool	NOUN
admet-1437	817	6	to	to	PART
admet-1437	817	7	guide	guide	VERB
admet-1437	817	8	lead	lead	ADJ
admet-1437	817	9	optimization	optimization	NOUN
admet-1437	817	10	for	for	ADP
admet-1437	817	11	orally	orally	ADV
admet-1437	817	12	bioavailable	bioavailable	ADJ
admet-1437	817	13	compounds	compound	NOUN
admet-1437	817	14	in	in	ADP
admet-1437	817	15	drug	drug	NOUN
admet-1437	817	16	discovery	discovery	NOUN
admet-1437	817	17	.	.	PUNCT
admet-1437	818	1	journal	journal	PROPN
admet-1437	818	2	of	of	ADP
admet-1437	818	3	medicinal	medicinal	ADJ
admet-1437	818	4	chemistry	chemistry	NOUN
admet-1437	818	5	65	65	NUM
admet-1437	818	6	(	(	PUNCT
admet-1437	818	7	2022	2022	NUM
admet-1437	818	8	)	)	PUNCT
admet-1437	818	9	1685	1685	NUM
admet-1437	818	10	-	-	SYM
admet-1437	818	11	1694	1694	NUM
admet-1437	818	12	.	.	PUNCT
admet-1437	819	1	https://doi.org/10.1021/acs.jmedchem.1c01687	https://doi.org/10.1021/acs.jmedchem.1c01687	NOUN
admet-1437	819	2	.	.	PUNCT
admet-1437	820	1	[	[	X
admet-1437	820	2	81	81	NUM
admet-1437	820	3	]	]	PUNCT
admet-1437	820	4	c.	c.	PROPN
admet-1437	820	5	konnerth	konnerth	PROPN
admet-1437	820	6	,	,	PUNCT
admet-1437	820	7	f.	f.	PROPN
admet-1437	820	8	flach	flach	PROPN
admet-1437	820	9	,	,	PUNCT
admet-1437	820	10	s.	s.	PROPN
admet-1437	820	11	breitung	breitung	PROPN
admet-1437	820	12	-	-	PUNCT
admet-1437	820	13	faes	faes	PROPN
admet-1437	820	14	,	,	PUNCT
admet-1437	820	15	c.	c.	PROPN
admet-1437	820	16	damm	damm	PROPN
admet-1437	820	17	,	,	PUNCT
admet-1437	820	18	j.	j.	PROPN
admet-1437	820	19	schmidt	schmidt	PROPN
admet-1437	820	20	,	,	PUNCT
admet-1437	820	21	a.	a.	NOUN
admet-1437	820	22	kwade	kwade	PROPN
admet-1437	820	23	,	,	PUNCT
admet-1437	820	24	w.	w.	PROPN
admet-1437	820	25	peukert	peukert	PROPN
admet-1437	820	26	.	.	PUNCT
admet-1437	821	1	impact	impact	NOUN
admet-1437	821	2	of	of	ADP
admet-1437	821	3	stressing	stress	VERB
admet-1437	821	4	conditions	condition	NOUN
admet-1437	821	5	and	and	CCONJ
admet-1437	821	6	polymer	polymer	NOUN
admet-1437	821	7	–	–	PUNCT
admet-1437	821	8	surfactant	surfactant	NOUN
admet-1437	821	9	interactions	interaction	NOUN
admet-1437	821	10	on	on	ADP
admet-1437	821	11	product	product	NOUN
admet-1437	821	12	characteristics	characteristic	NOUN
admet-1437	821	13	of	of	ADP
admet-1437	821	14	organic	organic	ADJ
admet-1437	821	15	nanoparticles	nanoparticle	NOUN
admet-1437	821	16	produced	produce	VERB
admet-1437	821	17	by	by	ADP
admet-1437	821	18	media	medium	NOUN
admet-1437	821	19	milling	milling	NOUN
admet-1437	821	20	.	.	PUNCT
admet-1437	822	1	powder	powder	NOUN
admet-1437	822	2	technology	technology	NOUN
admet-1437	822	3	294	294	NUM
admet-1437	822	4	(	(	PUNCT
admet-1437	822	5	2016	2016	NUM
admet-1437	822	6	)	)	PUNCT
admet-1437	822	7	71	71	NUM
admet-1437	822	8	-	-	SYM
admet-1437	822	9	79	79	NUM
admet-1437	822	10	.	.	PUNCT
admet-1437	823	1	https://doi.org/10.1016/j.powtec.2016.02.016	https://doi.org/10.1016/j.powtec.2016.02.016	PROPN
admet-1437	823	2	.	.	PUNCT
admet-1437	824	1	[	[	X
admet-1437	824	2	82	82	NUM
admet-1437	824	3	]	]	X
admet-1437	824	4	l.	l.	PROPN
admet-1437	824	5	peltonen	peltonen	PROPN
admet-1437	824	6	,	,	PUNCT
admet-1437	824	7	c.j	c.j	PROPN
admet-1437	824	8	.	.	PROPN
admet-1437	824	9	strachan	strachan	PROPN
admet-1437	824	10	.	.	PUNCT
admet-1437	825	1	degrees	degree	NOUN
admet-1437	825	2	of	of	ADP
admet-1437	825	3	order	order	NOUN
admet-1437	825	4	:	:	PUNCT
admet-1437	825	5	a	a	DET
admet-1437	825	6	comparison	comparison	NOUN
admet-1437	825	7	of	of	ADP
admet-1437	825	8	nanocrystal	nanocrystal	ADJ
admet-1437	825	9	and	and	CCONJ
admet-1437	825	10	amorphous	amorphous	ADJ
admet-1437	825	11	solids	solid	NOUN
admet-1437	825	12	for	for	ADP
admet-1437	825	13	poorly	poorly	ADV
admet-1437	825	14	soluble	soluble	ADJ
admet-1437	825	15	drugs	drug	NOUN
admet-1437	825	16	.	.	PUNCT
admet-1437	826	1	international	international	ADJ
admet-1437	826	2	journal	journal	PROPN
admet-1437	826	3	of	of	ADP
admet-1437	826	4	pharmaceutics	pharmaceutic	NOUN
admet-1437	826	5	586	586	NUM
admet-1437	826	6	(	(	PUNCT
admet-1437	826	7	2020	2020	NUM
admet-1437	826	8	)	)	PUNCT
admet-1437	826	9	119492	119492	NUM
admet-1437	826	10	.	.	PUNCT
admet-1437	827	1	https://doi.org/10.1016/j.ijpharm.2020.119492	https://doi.org/10.1016/j.ijpharm.2020.119492	PROPN
admet-1437	827	2	.	.	PUNCT
admet-1437	828	1	[	[	X
admet-1437	828	2	83	83	NUM
admet-1437	828	3	]	]	PUNCT
admet-1437	828	4	j.	j.	PROPN
admet-1437	828	5	jinno	jinno	PROPN
admet-1437	828	6	,	,	PUNCT
admet-1437	828	7	n.	n.	PROPN
admet-1437	828	8	kamada	kamada	PROPN
admet-1437	828	9	,	,	PUNCT
admet-1437	828	10	m.	m.	PROPN
admet-1437	828	11	miyake	miyake	PROPN
admet-1437	828	12	,	,	PUNCT
admet-1437	828	13	k.	k.	PROPN
admet-1437	828	14	yamada	yamada	PROPN
admet-1437	828	15	,	,	PUNCT
admet-1437	828	16	t.	t.	PROPN
admet-1437	828	17	mukai	mukai	PROPN
admet-1437	828	18	,	,	PUNCT
admet-1437	828	19	m.	m.	NOUN
admet-1437	828	20	odomi	odomi	PROPN
admet-1437	828	21	,	,	PUNCT
admet-1437	828	22	h.	h.	PROPN
admet-1437	828	23	toguchi	toguchi	PROPN
admet-1437	828	24	,	,	PUNCT
admet-1437	828	25	g.g	g.g	PROPN
admet-1437	828	26	.	.	PROPN
admet-1437	828	27	liversidge	liversidge	PROPN
admet-1437	828	28	,	,	PUNCT
admet-1437	828	29	k.	k.	PROPN
admet-1437	828	30	higaki	higaki	PROPN
admet-1437	828	31	,	,	PUNCT
admet-1437	828	32	t.	t.	PROPN
admet-1437	828	33	kimura	kimura	NOUN
admet-1437	828	34	.	.	PUNCT
admet-1437	829	1	effect	effect	NOUN
admet-1437	829	2	of	of	ADP
admet-1437	829	3	particle	particle	NOUN
admet-1437	829	4	size	size	NOUN
admet-1437	829	5	reduction	reduction	NOUN
admet-1437	829	6	on	on	ADP
admet-1437	829	7	dissolution	dissolution	NOUN
admet-1437	829	8	and	and	CCONJ
admet-1437	829	9	oral	oral	ADJ
admet-1437	829	10	absorption	absorption	NOUN
admet-1437	829	11	of	of	ADP
admet-1437	829	12	a	a	DET
admet-1437	829	13	poorly	poorly	ADV
admet-1437	829	14	water	water	NOUN
admet-1437	829	15	-	-	PUNCT
admet-1437	829	16	soluble	soluble	ADJ
admet-1437	829	17	drug	drug	NOUN
admet-1437	829	18	,	,	PUNCT
admet-1437	829	19	cilostazol	cilostazol	ADJ
admet-1437	829	20	,	,	PUNCT
admet-1437	829	21	in	in	ADP
admet-1437	829	22	beagle	beagle	NOUN
admet-1437	829	23	dogs	dog	NOUN
admet-1437	829	24	.	.	PUNCT
admet-1437	830	1	journal	journal	NOUN
admet-1437	830	2	of	of	ADP
admet-1437	830	3	controlled	control	VERB
admet-1437	830	4	release	release	NOUN
admet-1437	830	5	111	111	NUM
admet-1437	830	6	(	(	PUNCT
admet-1437	830	7	2006	2006	NUM
admet-1437	830	8	)	)	PUNCT
admet-1437	830	9	56	56	NUM
admet-1437	830	10	-	-	SYM
admet-1437	830	11	64	64	NUM
admet-1437	830	12	.	.	PUNCT
admet-1437	831	1	https://doi.org/10.1016/j.jconrel.2005.11.013	https://doi.org/10.1016/j.jconrel.2005.11.013	NOUN
admet-1437	831	2	.	.	PUNCT
admet-1437	832	1	[	[	X
admet-1437	832	2	84	84	NUM
admet-1437	832	3	]	]	PUNCT
admet-1437	832	4	m.	m.	NOUN
admet-1437	832	5	koziolek	koziolek	NOUN
admet-1437	832	6	,	,	PUNCT
admet-1437	832	7	m.	m.	NOUN
admet-1437	832	8	grimm	grimm	PROPN
admet-1437	832	9	,	,	PUNCT
admet-1437	832	10	f.	f.	PROPN
admet-1437	832	11	schneider	schneider	PROPN
admet-1437	832	12	,	,	PUNCT
admet-1437	832	13	p.	p.	PROPN
admet-1437	832	14	jedamzik	jedamzik	NOUN
admet-1437	832	15	,	,	PUNCT
admet-1437	832	16	m.	m.	NOUN
admet-1437	832	17	sager	sager	PROPN
admet-1437	832	18	,	,	PUNCT
admet-1437	832	19	j.p	j.p	PROPN
admet-1437	832	20	.	.	PROPN
admet-1437	832	21	kühn	kühn	PROPN
admet-1437	832	22	,	,	PUNCT
admet-1437	832	23	w.	w.	PROPN
admet-1437	832	24	siegmund	siegmund	PROPN
admet-1437	832	25	,	,	PUNCT
admet-1437	832	26	w.	w.	PROPN
admet-1437	832	27	weitschies	weitschie	NOUN
admet-1437	832	28	.	.	PUNCT
admet-1437	833	1	navigating	navigate	VERB
admet-1437	833	2	the	the	DET
admet-1437	833	3	human	human	ADJ
admet-1437	833	4	gastrointestinal	gastrointestinal	ADJ
admet-1437	833	5	tract	tract	NOUN
admet-1437	833	6	for	for	ADP
admet-1437	833	7	oral	oral	ADJ
admet-1437	833	8	drug	drug	NOUN
admet-1437	833	9	delivery	delivery	NOUN
admet-1437	833	10	:	:	PUNCT
admet-1437	833	11	uncharted	uncharted	ADJ
admet-1437	833	12	waters	water	NOUN
admet-1437	833	13	and	and	CCONJ
admet-1437	833	14	new	new	ADJ
admet-1437	833	15	frontiers	frontier	NOUN
admet-1437	833	16	.	.	PUNCT
admet-1437	834	1	advanced	advanced	ADJ
admet-1437	834	2	drug	drug	NOUN
admet-1437	834	3	delivery	delivery	NOUN
admet-1437	834	4	reviews	review	VERB
admet-1437	834	5	101	101	NUM
admet-1437	834	6	(	(	PUNCT
admet-1437	834	7	2016	2016	NUM
admet-1437	834	8	)	)	PUNCT
admet-1437	834	9	75	75	NUM
admet-1437	834	10	-	-	SYM
admet-1437	834	11	88	88	NUM
admet-1437	834	12	.	.	PUNCT
admet-1437	835	1	https://doi.org/10.1016/-j.addr.2016.03.009	https://doi.org/10.1016/-j.addr.2016.03.009	NOUN
admet-1437	835	2	.	.	PUNCT
admet-1437	836	1	[	[	X
admet-1437	836	2	85	85	NUM
admet-1437	836	3	]	]	X
admet-1437	836	4	m.	m.	NOUN
admet-1437	836	5	vertzoni	vertzoni	PROPN
admet-1437	836	6	,	,	PUNCT
admet-1437	836	7	p.	p.	NOUN
admet-1437	836	8	augustijns	augustijns	NOUN
admet-1437	836	9	,	,	PUNCT
admet-1437	836	10	m.	m.	NOUN
admet-1437	836	11	grimm	grimm	NOUN
admet-1437	836	12	,	,	PUNCT
admet-1437	836	13	m.	m.	NOUN
admet-1437	836	14	koziolek	koziolek	NOUN
admet-1437	836	15	,	,	PUNCT
admet-1437	836	16	g.	g.	PROPN
admet-1437	836	17	lemmens	lemmens	PROPN
admet-1437	836	18	,	,	PUNCT
admet-1437	836	19	n.	n.	PROPN
admet-1437	836	20	parrott	parrott	PROPN
admet-1437	836	21	,	,	PUNCT
admet-1437	836	22	c.	c.	PROPN
admet-1437	836	23	pentafragka	pentafragka	PROPN
admet-1437	836	24	,	,	PUNCT
admet-1437	836	25	c.	c.	PROPN
admet-1437	836	26	reppas	reppas	PROPN
admet-1437	836	27	,	,	PUNCT
admet-1437	836	28	j.	j.	PROPN
admet-1437	836	29	rubbens	rubbens	PROPN
admet-1437	836	30	,	,	PUNCT
admet-1437	836	31	j.	j.	PROPN
admet-1437	836	32	van	van	PROPN
admet-1437	836	33	den	den	PROPN
admet-1437	836	34	αbeele	αbeele	PROPN
admet-1437	836	35	,	,	PUNCT
admet-1437	836	36	t.	t.	PROPN
admet-1437	836	37	vanuytsel	vanuytsel	NOUN
admet-1437	836	38	,	,	PUNCT
admet-1437	836	39	w.	w.	PROPN
admet-1437	836	40	weitschies	weitschie	NOUN
admet-1437	836	41	,	,	PUNCT
admet-1437	836	42	c.g	c.g	PROPN
admet-1437	836	43	.	.	PROPN
admet-1437	836	44	wilson	wilson	PROPN
admet-1437	836	45	.	.	PUNCT
admet-1437	837	1	impact	impact	NOUN
admet-1437	837	2	of	of	ADP
admet-1437	837	3	regional	regional	ADJ
admet-1437	837	4	differences	difference	NOUN
admet-1437	837	5	along	along	ADP
admet-1437	837	6	the	the	DET
admet-1437	837	7	gastrointestinal	gastrointestinal	ADJ
admet-1437	837	8	tract	tract	NOUN
admet-1437	837	9	of	of	ADP
admet-1437	837	10	healthy	healthy	ADJ
admet-1437	837	11	adults	adult	NOUN
admet-1437	837	12	on	on	ADP
admet-1437	837	13	oral	oral	ADJ
admet-1437	837	14	drug	drug	NOUN
admet-1437	837	15	absorption	absorption	NOUN
admet-1437	837	16	:	:	PUNCT
admet-1437	837	17	an	an	DET
admet-1437	837	18	ungap	ungap	NOUN
admet-1437	837	19	review	review	NOUN
admet-1437	837	20	.	.	PUNCT
admet-1437	838	1	european	european	PROPN
admet-1437	838	2	journal	journal	PROPN
admet-1437	838	3	of	of	ADP
admet-1437	838	4	pharmaceutical	pharmaceutical	PROPN
admet-1437	838	5	sciences	science	NOUN
admet-1437	838	6	134	134	NUM
admet-1437	838	7	(	(	PUNCT
admet-1437	838	8	2019	2019	NUM
admet-1437	838	9	)	)	PUNCT
admet-1437	838	10	153	153	NUM
admet-1437	838	11	-	-	SYM
admet-1437	838	12	175	175	NUM
admet-1437	838	13	.	.	PUNCT
admet-1437	839	1	https://doi.org/10.1016/-j.ejps.2019.04.013	https://doi.org/10.1016/-j.ejps.2019.04.013	PROPN
admet-1437	839	2	.	.	PUNCT
admet-1437	840	1	[	[	X
admet-1437	840	2	86	86	NUM
admet-1437	840	3	]	]	PUNCT
admet-1437	840	4	z.	z.	PROPN
admet-1437	840	5	vinarov	vinarov	PROPN
admet-1437	840	6	,	,	PUNCT
admet-1437	840	7	m.	m.	NOUN
admet-1437	840	8	abdallah	abdallah	PROPN
admet-1437	840	9	,	,	PUNCT
admet-1437	840	10	j.a.g	j.a.g	PROPN
admet-1437	840	11	.	.	PUNCT
admet-1437	840	12	agundez	agundez	PROPN
admet-1437	840	13	,	,	PUNCT
admet-1437	840	14	k.	k.	PROPN
admet-1437	840	15	allegaert	allegaert	PROPN
admet-1437	840	16	,	,	PUNCT
admet-1437	840	17	a.w	a.w	PROPN
admet-1437	840	18	.	.	PROPN
admet-1437	840	19	basit	basit	PROPN
admet-1437	840	20	,	,	PUNCT
admet-1437	840	21	m.	m.	NOUN
admet-1437	840	22	braeckmans	braeckman	NOUN
admet-1437	840	23	,	,	PUNCT
admet-1437	840	24	j.	j.	PROPN
admet-1437	840	25	ceulemans	ceulemans	PROPN
admet-1437	840	26	,	,	PUNCT
admet-1437	840	27	m.	m.	PROPN
admet-1437	840	28	corsetti	corsetti	PROPN
admet-1437	840	29	,	,	PUNCT
admet-1437	840	30	b.t	b.t	PROPN
admet-1437	840	31	.	.	PROPN
admet-1437	840	32	griffin	griffin	PROPN
admet-1437	840	33	,	,	PUNCT
admet-1437	840	34	m.	m.	NOUN
admet-1437	840	35	grimm	grimm	PROPN
admet-1437	840	36	,	,	PUNCT
admet-1437	840	37	d.	d.	PROPN
admet-1437	840	38	keszthelyi	keszthelyi	PROPN
admet-1437	840	39	,	,	PUNCT
admet-1437	840	40	m.	m.	NOUN
admet-1437	840	41	koziolek	koziolek	PROPN
admet-1437	840	42	,	,	PUNCT
admet-1437	840	43	c.m	c.m	PROPN
admet-1437	840	44	.	.	PROPN
admet-1437	840	45	madla	madla	PROPN
admet-1437	840	46	,	,	PUNCT
admet-1437	840	47	c.	c.	PROPN
admet-1437	840	48	matthys	matthys	PROPN
admet-1437	840	49	,	,	PUNCT
admet-1437	840	50	l.e	l.e	PROPN
admet-1437	840	51	.	.	PROPN
admet-1437	840	52	mccoubrey	mccoubrey	PROPN
admet-1437	840	53	,	,	PUNCT
admet-1437	840	54	a.	a.	PROPN
admet-1437	840	55	mitra	mitra	PROPN
admet-1437	840	56	,	,	PUNCT
admet-1437	840	57	c.	c.	PROPN
admet-1437	840	58	reppas	reppas	PROPN
admet-1437	840	59	,	,	PUNCT
admet-1437	840	60	j.	j.	PROPN
admet-1437	840	61	stappaerts	stappaerts	PROPN
admet-1437	840	62	,	,	PUNCT
admet-1437	840	63	n.	n.	PROPN
admet-1437	840	64	steenackers	steenacker	NOUN
admet-1437	840	65	,	,	PUNCT
admet-1437	840	66	n.l	n.l	PROPN
admet-1437	840	67	.	.	PROPN
admet-1437	840	68	trevaskis	trevaskis	PROPN
admet-1437	840	69	,	,	PUNCT
admet-1437	840	70	t.	t.	NOUN
admet-1437	840	71	vanuytsel	vanuytsel	NOUN
admet-1437	840	72	,	,	PUNCT
admet-1437	840	73	m.	m.	NOUN
admet-1437	840	74	vertzoni	vertzoni	PROPN
admet-1437	840	75	,	,	PUNCT
admet-1437	840	76	w.	w.	PROPN
admet-1437	840	77	weitschies	weitschie	NOUN
admet-1437	840	78	,	,	PUNCT
admet-1437	840	79	c.	c.	PROPN
admet-1437	840	80	wilson	wilson	PROPN
admet-1437	840	81	,	,	PUNCT
admet-1437	840	82	p.	p.	NOUN
admet-1437	840	83	augustijns	augustijns	NOUN
admet-1437	840	84	.	.	PUNCT
admet-1437	841	1	impact	impact	NOUN
admet-1437	841	2	of	of	ADP
admet-1437	841	3	gastrointestinal	gastrointestinal	ADJ
admet-1437	841	4	tract	tract	NOUN
admet-1437	841	5	variability	variability	NOUN
admet-1437	841	6	on	on	ADP
admet-1437	841	7	oral	oral	ADJ
admet-1437	841	8	drug	drug	NOUN
admet-1437	841	9	absorption	absorption	NOUN
admet-1437	841	10	and	and	CCONJ
admet-1437	841	11	https://doi.org/10.1002/jps.24487	https://doi.org/10.1002/jps.24487	PROPN
admet-1437	841	12	https://doi.org/10.1039/tf9221700457	https://doi.org/10.1039/tf9221700457	PROPN
admet-1437	841	13	https://doi.org/10.1023/a:1018947113238	https://doi.org/10.1023/a:1018947113238	NOUN
admet-1437	841	14	https://doi.org/10.1016/0169-409x(96)00009-9	https://doi.org/10.1016/0169-409x(96)00009-9	PROPN
admet-1437	841	15	https://doi.org/10.1002/jps.22217	https://doi.org/10.1002/jps.22217	PROPN
admet-1437	841	16	https://doi.org/10.1208/s12248-011-9290-9	https://doi.org/10.1208/s12248-011-9290-9	PROPN
admet-1437	841	17	https://doi.org/10.1021/mp500504q	https://doi.org/10.1021/mp500504q	NOUN
admet-1437	841	18	https://doi.org/10.1002/jps.24391	https://doi.org/10.1002/jps.24391	VERB
admet-1437	841	19	https://doi.org/10.1016/j.xphs.2018.03.030	https://doi.org/10.1016/j.xphs.2018.03.030	PRON
admet-1437	841	20	https://doi.org/10.1021/acs.jmedchem.1c01687	https://doi.org/10.1021/acs.jmedchem.1c01687	NOUN
admet-1437	841	21	https://doi.org/10.1021/acs.jmedchem.1c01687	https://doi.org/10.1021/acs.jmedchem.1c01687	NOUN
admet-1437	841	22	https://doi.org/10.1016/j.powtec.2016.02.016	https://doi.org/10.1016/j.powtec.2016.02.016	PROPN
admet-1437	841	23	https://doi.org/10.1016/j.powtec.2016.02.016	https://doi.org/10.1016/j.powtec.2016.02.016	VERB
admet-1437	841	24	https://doi.org/10.1016/j.ijpharm.2020.119492	https://doi.org/10.1016/j.ijpharm.2020.119492	PROPN
admet-1437	841	25	https://doi.org/10.1016/j.ijpharm.2020.119492	https://doi.org/10.1016/j.ijpharm.2020.119492	PROPN
admet-1437	841	26	https://doi.org/10.1016/j.jconrel.2005.11.013	https://doi.org/10.1016/j.jconrel.2005.11.013	PROPN
admet-1437	841	27	https://doi.org/10.1016/j.jconrel.2005.11.013	https://doi.org/10.1016/j.jconrel.2005.11.013	PROPN
admet-1437	841	28	https://doi.org/10.1016/j.addr.2016.03.009	https://doi.org/10.1016/j.addr.2016.03.009	VERB
admet-1437	841	29	https://doi.org/10.1016/j.ejps.2019.04.013	https://doi.org/10.1016/j.ejps.2019.04.013	PROPN
admet-1437	841	30	admet	admet	PROPN
admet-1437	841	31	&	&	CCONJ
admet-1437	841	32	dmpk	dmpk	PROPN
admet-1437	841	33	10(4	10(4	NUM
admet-1437	841	34	)	)	PUNCT
admet-1437	841	35	(	(	PUNCT
admet-1437	841	36	2022	2022	NUM
admet-1437	841	37	)	)	PUNCT
admet-1437	841	38	253	253	NUM
admet-1437	841	39	-	-	SYM
admet-1437	841	40	287	287	NUM
admet-1437	841	41	modeling	modeling	NOUN
admet-1437	841	42	of	of	ADP
admet-1437	841	43	drug	drug	NOUN
admet-1437	841	44	nanocrystals	nanocrystal	NOUN
admet-1437	841	45	dissolution	dissolution	NOUN
admet-1437	841	46	doi	doi	PROPN
admet-1437	841	47	:	:	PUNCT
admet-1437	841	48	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	PUNCT
admet-1437	841	49	287	287	NUM
admet-1437	841	50	pharmacokinetics	pharmacokinetic	NOUN
admet-1437	841	51	:	:	PUNCT
admet-1437	841	52	an	an	DET
admet-1437	841	53	ungap	ungap	NOUN
admet-1437	841	54	review	review	NOUN
admet-1437	841	55	.	.	PUNCT
admet-1437	842	1	european	european	PROPN
admet-1437	842	2	journal	journal	PROPN
admet-1437	842	3	of	of	ADP
admet-1437	842	4	pharmaceutical	pharmaceutical	PROPN
admet-1437	842	5	sciences	science	NOUN
admet-1437	842	6	162	162	NUM
admet-1437	842	7	(	(	PUNCT
admet-1437	842	8	2021	2021	NUM
admet-1437	842	9	)	)	PUNCT
admet-1437	842	10	105812	105812	NUM
admet-1437	842	11	.	.	PUNCT
admet-1437	843	1	https://doi.org/10.1016/j.ejps.2021.105812	https://doi.org/10.1016/j.ejps.2021.105812	NOUN
admet-1437	843	2	.	.	PUNCT
admet-1437	844	1	[	[	X
admet-1437	844	2	87	87	NUM
admet-1437	844	3	]	]	PUNCT
admet-1437	844	4	j.	j.	PROPN
admet-1437	844	5	brouwers	brouwers	PROPN
admet-1437	844	6	,	,	PUNCT
admet-1437	844	7	m.e	m.e	PROPN
admet-1437	844	8	.	.	PROPN
admet-1437	844	9	brewster	brewster	PROPN
admet-1437	844	10	,	,	PUNCT
admet-1437	844	11	p.	p.	NOUN
admet-1437	844	12	augustijns	augustijns	NOUN
admet-1437	844	13	.	.	PUNCT
admet-1437	845	1	supersaturating	supersaturate	VERB
admet-1437	845	2	drug	drug	NOUN
admet-1437	845	3	delivery	delivery	NOUN
admet-1437	845	4	systems	system	NOUN
admet-1437	845	5	:	:	PUNCT
admet-1437	845	6	the	the	DET
admet-1437	845	7	answer	answer	NOUN
admet-1437	845	8	to	to	ADP
admet-1437	845	9	solubility	solubility	NOUN
admet-1437	845	10	-	-	PUNCT
admet-1437	845	11	limited	limit	VERB
admet-1437	845	12	oral	oral	ADJ
admet-1437	845	13	bioavailability	bioavailability	NOUN
admet-1437	845	14	?	?	PUNCT
admet-1437	846	1	journal	journal	NOUN
admet-1437	846	2	of	of	ADP
admet-1437	846	3	pharmaceutical	pharmaceutical	ADJ
admet-1437	846	4	sciences	science	NOUN
admet-1437	846	5	98	98	NUM
admet-1437	846	6	(	(	PUNCT
admet-1437	846	7	2009	2009	NUM
admet-1437	846	8	)	)	PUNCT
admet-1437	846	9	2549	2549	NUM
admet-1437	846	10	-	-	SYM
admet-1437	846	11	2572	2572	NUM
admet-1437	846	12	.	.	PUNCT
admet-1437	847	1	https://doi.org/10.1002/jps.21650	https://doi.org/10.1002/jps.21650	NOUN
admet-1437	847	2	.	.	PUNCT
admet-1437	848	1	[	[	X
admet-1437	848	2	88	88	NUM
admet-1437	848	3	]	]	X
admet-1437	848	4	l.s	l.s	PROPN
admet-1437	848	5	.	.	PROPN
admet-1437	848	6	taylor	taylor	PROPN
admet-1437	848	7	,	,	PUNCT
admet-1437	848	8	g.g.z	g.g.z	PROPN
admet-1437	848	9	.	.	PUNCT
admet-1437	849	1	zhang	zhang	PROPN
admet-1437	849	2	.	.	PUNCT
admet-1437	850	1	physical	physical	ADJ
admet-1437	850	2	chemistry	chemistry	NOUN
admet-1437	850	3	of	of	ADP
admet-1437	850	4	supersaturated	supersaturated	ADJ
admet-1437	850	5	solutions	solution	NOUN
admet-1437	850	6	and	and	CCONJ
admet-1437	850	7	implications	implication	NOUN
admet-1437	850	8	for	for	ADP
admet-1437	850	9	oral	oral	ADJ
admet-1437	850	10	absorption	absorption	NOUN
admet-1437	850	11	.	.	PUNCT
admet-1437	851	1	advanced	advanced	ADJ
admet-1437	851	2	drug	drug	NOUN
admet-1437	851	3	delivery	delivery	NOUN
admet-1437	851	4	reviews	review	VERB
admet-1437	851	5	101	101	NUM
admet-1437	851	6	(	(	PUNCT
admet-1437	851	7	2016	2016	NUM
admet-1437	851	8	)	)	PUNCT
admet-1437	851	9	122	122	NUM
admet-1437	851	10	-	-	SYM
admet-1437	851	11	142	142	NUM
admet-1437	851	12	.	.	PUNCT
admet-1437	852	1	https://doi.org/10.1016/j.addr.2016.03.006	https://doi.org/10.1016/j.addr.2016.03.006	NOUN
admet-1437	852	2	.	.	PUNCT
admet-1437	853	1	[	[	X
admet-1437	853	2	89	89	NUM
admet-1437	853	3	]	]	X
admet-1437	853	4	b.j	b.j	PROPN
admet-1437	853	5	.	.	PROPN
admet-1437	853	6	boyd	boyd	PROPN
admet-1437	853	7	,	,	PUNCT
admet-1437	853	8	c.a.s	c.a.s	PROPN
admet-1437	853	9	.	.	PROPN
admet-1437	853	10	bergström	bergström	PROPN
admet-1437	853	11	,	,	PUNCT
admet-1437	853	12	z.	z.	PROPN
admet-1437	853	13	vinarov	vinarov	PROPN
admet-1437	853	14	,	,	PUNCT
admet-1437	853	15	m.	m.	NOUN
admet-1437	853	16	kuentz	kuentz	PROPN
admet-1437	853	17	,	,	PUNCT
admet-1437	853	18	j.	j.	PROPN
admet-1437	853	19	brouwers	brouwers	PROPN
admet-1437	853	20	,	,	PUNCT
admet-1437	853	21	p.	p.	NOUN
admet-1437	853	22	augustijns	augustijns	NOUN
admet-1437	853	23	,	,	PUNCT
admet-1437	853	24	m.	m.	NOUN
admet-1437	853	25	brandl	brandl	PROPN
admet-1437	853	26	,	,	PUNCT
admet-1437	853	27	a.	a.	NOUN
admet-1437	853	28	bernkopschnürch	bernkopschnürch	PROPN
admet-1437	853	29	,	,	PUNCT
admet-1437	853	30	n.	n.	PROPN
admet-1437	853	31	shrestha	shrestha	PROPN
admet-1437	853	32	,	,	PUNCT
admet-1437	853	33	v.	v.	ADP
admet-1437	853	34	préat	préat	PROPN
admet-1437	853	35	,	,	PUNCT
admet-1437	853	36	a.	a.	NOUN
admet-1437	853	37	müllertz	müllertz	PROPN
admet-1437	853	38	,	,	PUNCT
admet-1437	853	39	a.	a.	PROPN
admet-1437	853	40	bauer	bauer	PROPN
admet-1437	853	41	-	-	PUNCT
admet-1437	853	42	brandl	brandl	PROPN
admet-1437	853	43	,	,	PUNCT
admet-1437	853	44	vi	vi	PROPN
admet-1437	853	45	.	.	PUNCT
admet-1437	853	46	jannin	jannin	NOUN
admet-1437	853	47	.	.	PUNCT
admet-1437	854	1	successful	successful	ADJ
admet-1437	854	2	oral	oral	ADJ
admet-1437	854	3	delivery	delivery	NOUN
admet-1437	854	4	of	of	ADP
admet-1437	854	5	poorly	poorly	ADV
admet-1437	854	6	water	water	NOUN
admet-1437	854	7	-	-	PUNCT
admet-1437	854	8	soluble	soluble	ADJ
admet-1437	854	9	drugs	drug	NOUN
admet-1437	854	10	both	both	PRON
admet-1437	854	11	depends	depend	VERB
admet-1437	854	12	on	on	ADP
admet-1437	854	13	the	the	DET
admet-1437	854	14	intraluminal	intraluminal	ADJ
admet-1437	854	15	behavior	behavior	NOUN
admet-1437	854	16	of	of	ADP
admet-1437	854	17	drugs	drug	NOUN
admet-1437	854	18	and	and	CCONJ
admet-1437	854	19	of	of	ADP
admet-1437	854	20	appropriate	appropriate	ADJ
admet-1437	854	21	advanced	advanced	ADJ
admet-1437	854	22	drug	drug	NOUN
admet-1437	854	23	delivery	delivery	NOUN
admet-1437	854	24	systems	system	NOUN
admet-1437	854	25	.	.	PUNCT
admet-1437	855	1	european	european	ADJ
admet-1437	855	2	journal	journal	PROPN
admet-1437	855	3	of	of	ADP
admet-1437	855	4	pharmaceutical	pharmaceutical	PROPN
admet-1437	855	5	sciences	science	NOUN
admet-1437	855	6	137	137	NUM
admet-1437	855	7	(	(	PUNCT
admet-1437	855	8	2019	2019	NUM
admet-1437	855	9	)	)	PUNCT
admet-1437	855	10	104967	104967	NUM
admet-1437	855	11	.	.	PUNCT
admet-1437	856	1	https://doi.org/10.1016/j.ejps.2019.104967	https://doi.org/10.1016/j.ejps.2019.104967	NOUN
admet-1437	856	2	.	.	PUNCT
admet-1437	857	1	[	[	X
admet-1437	857	2	90	90	NUM
admet-1437	857	3	]	]	PUNCT
admet-1437	857	4	z.	z.	PROPN
admet-1437	857	5	vinarov	vinarov	PROPN
admet-1437	857	6	,	,	PUNCT
admet-1437	857	7	b.	b.	PROPN
admet-1437	857	8	abrahamsson	abrahamsson	PROPN
admet-1437	857	9	,	,	PUNCT
admet-1437	857	10	p.	p.	PROPN
admet-1437	857	11	artursson	artursson	PROPN
admet-1437	857	12	,	,	PUNCT
admet-1437	857	13	h.	h.	PROPN
admet-1437	857	14	batchelor	batchelor	PROPN
admet-1437	857	15	,	,	PUNCT
admet-1437	857	16	p.	p.	PROPN
admet-1437	857	17	berben	berben	PROPN
admet-1437	857	18	,	,	PUNCT
admet-1437	857	19	a.	a.	PROPN
admet-1437	857	20	bernkop	bernkop	PROPN
admet-1437	857	21	-	-	PUNCT
admet-1437	857	22	schnürch	schnürch	NOUN
admet-1437	857	23	,	,	PUNCT
admet-1437	857	24	j.	j.	PROPN
admet-1437	857	25	butler	butler	PROPN
admet-1437	857	26	,	,	PUNCT
admet-1437	857	27	j.	j.	PROPN
admet-1437	857	28	ceulemans	ceulemans	PROPN
admet-1437	857	29	,	,	PUNCT
admet-1437	857	30	n.	n.	PROPN
admet-1437	857	31	davies	davy	NOUN
admet-1437	857	32	,	,	PUNCT
admet-1437	857	33	d.	d.	PROPN
admet-1437	857	34	dupont	dupont	PROPN
admet-1437	857	35	,	,	PUNCT
admet-1437	857	36	g.	g.	PROPN
admet-1437	857	37	eide	eide	PROPN
admet-1437	857	38	flaten	flaten	PROPN
admet-1437	857	39	,	,	PUNCT
admet-1437	857	40	n.	n.	PROPN
admet-1437	857	41	fotaki	fotaki	PROPN
admet-1437	857	42	,	,	PUNCT
admet-1437	857	43	b.t	b.t	PROPN
admet-1437	857	44	.	.	PROPN
admet-1437	857	45	griffin	griffin	PROPN
admet-1437	857	46	,	,	PUNCT
admet-1437	857	47	v.	v.	PROPN
admet-1437	857	48	jannin	jannin	PROPN
admet-1437	857	49	,	,	PUNCT
admet-1437	857	50	j.	j.	PROPN
admet-1437	857	51	keemink	keemink	PROPN
admet-1437	857	52	,	,	PUNCT
admet-1437	857	53	f.	f.	PROPN
admet-1437	857	54	kesisoglou	kesisoglou	PROPN
admet-1437	857	55	,	,	PUNCT
admet-1437	857	56	m.	m.	NOUN
admet-1437	857	57	koziolek	koziolek	NOUN
admet-1437	857	58	,	,	PUNCT
admet-1437	857	59	m.	m.	NOUN
admet-1437	857	60	kuentz	kuentz	PROPN
admet-1437	857	61	,	,	PUNCT
admet-1437	857	62	a.	a.	NOUN
admet-1437	857	63	mackie	mackie	PROPN
admet-1437	857	64	,	,	PUNCT
admet-1437	857	65	a.j	a.j	PROPN
admet-1437	857	66	.	.	PROPN
admet-1437	857	67	meléndez	meléndez	PROPN
admet-1437	857	68	-	-	PUNCT
admet-1437	857	69	martínez	martínez	PROPN
admet-1437	857	70	,	,	PUNCT
admet-1437	857	71	m.	m.	NOUN
admet-1437	857	72	mcallister	mcallister	PROPN
admet-1437	857	73	,	,	PUNCT
admet-1437	857	74	a.	a.	NOUN
admet-1437	857	75	müllertz	müllertz	PROPN
admet-1437	857	76	,	,	PUNCT
admet-1437	857	77	c.m	c.m	PROPN
admet-1437	857	78	.	.	PROPN
admet-1437	857	79	o'driscoll	o'driscoll	PROPN
admet-1437	857	80	,	,	PUNCT
admet-1437	857	81	n.	n.	PROPN
admet-1437	857	82	parrott	parrott	PROPN
admet-1437	857	83	,	,	PUNCT
admet-1437	857	84	j.	j.	PROPN
admet-1437	857	85	paszkowska	paszkowska	PROPN
admet-1437	857	86	,	,	PUNCT
admet-1437	857	87	p.	p.	NOUN
admet-1437	857	88	pavek	pavek	NOUN
admet-1437	857	89	,	,	PUNCT
admet-1437	857	90	c.j.h	c.j.h	ADJ
admet-1437	857	91	.	.	PUNCT
admet-1437	857	92	porter	porter	PROPN
admet-1437	857	93	,	,	PUNCT
admet-1437	857	94	c.	c.	PROPN
admet-1437	857	95	reppas	reppas	PROPN
admet-1437	857	96	,	,	PUNCT
admet-1437	857	97	c.	c.	PROPN
admet-1437	857	98	stillhart	stillhart	PROPN
admet-1437	857	99	,	,	PUNCT
admet-1437	857	100	k.	k.	PROPN
admet-1437	857	101	sugano	sugano	PROPN
admet-1437	857	102	,	,	PUNCT
admet-1437	857	103	e.	e.	PROPN
admet-1437	857	104	toader	toader	PROPN
admet-1437	857	105	,	,	PUNCT
admet-1437	857	106	k.	k.	PROPN
admet-1437	857	107	valentová	valentová	PROPN
admet-1437	857	108	,	,	PUNCT
admet-1437	857	109	m.	m.	NOUN
admet-1437	857	110	vertzoni	vertzoni	PROPN
admet-1437	857	111	,	,	PUNCT
admet-1437	857	112	s.n	s.n	PROPN
admet-1437	857	113	.	.	PROPN
admet-1437	857	114	de	de	X
admet-1437	857	115	wildt	wildt	PROPN
admet-1437	857	116	,	,	PUNCT
admet-1437	857	117	c.g	c.g	PROPN
admet-1437	857	118	.	.	PROPN
admet-1437	857	119	wilson	wilson	PROPN
admet-1437	857	120	,	,	PUNCT
admet-1437	857	121	p.	p.	NOUN
admet-1437	857	122	augustijns	augustijns	NOUN
admet-1437	857	123	.	.	PUNCT
admet-1437	858	1	current	current	ADJ
admet-1437	858	2	challenges	challenge	NOUN
admet-1437	858	3	and	and	CCONJ
admet-1437	858	4	future	future	ADJ
admet-1437	858	5	perspectives	perspective	NOUN
admet-1437	858	6	in	in	ADP
admet-1437	858	7	oral	oral	ADJ
admet-1437	858	8	absorption	absorption	NOUN
admet-1437	858	9	research	research	NOUN
admet-1437	858	10	:	:	PUNCT
admet-1437	858	11	an	an	DET
admet-1437	858	12	opinion	opinion	NOUN
admet-1437	858	13	of	of	ADP
admet-1437	858	14	the	the	DET
admet-1437	858	15	ungap	ungap	NOUN
admet-1437	858	16	network	network	NOUN
admet-1437	858	17	.	.	PUNCT
admet-1437	859	1	advanced	advanced	ADJ
admet-1437	859	2	drug	drug	NOUN
admet-1437	859	3	delivery	delivery	NOUN
admet-1437	859	4	reviews	review	NOUN
admet-1437	859	5	171	171	NUM
admet-1437	859	6	(	(	PUNCT
admet-1437	859	7	2021	2021	NUM
admet-1437	859	8	)	)	PUNCT
admet-1437	859	9	289	289	NUM
admet-1437	859	10	-	-	SYM
admet-1437	859	11	331	331	NUM
admet-1437	859	12	.	.	PUNCT
admet-1437	860	1	https://doi.org/10.1016/j.addr.2021.02.001	https://doi.org/10.1016/j.addr.2021.02.001	PROPN
admet-1437	860	2	.	.	PUNCT
admet-1437	861	1	©	©	NOUN
admet-1437	861	2	2022	2022	NUM
admet-1437	861	3	by	by	ADP
admet-1437	861	4	the	the	DET
admet-1437	861	5	authors	author	NOUN
admet-1437	861	6	;	;	PUNCT
admet-1437	861	7	licensee	licensee	PROPN
admet-1437	861	8	iapc	iapc	PROPN
admet-1437	861	9	,	,	PUNCT
admet-1437	861	10	zagreb	zagreb	PROPN
admet-1437	861	11	,	,	PUNCT
admet-1437	861	12	croatia	croatia	PROPN
admet-1437	861	13	.	.	PUNCT
admet-1437	862	1	this	this	DET
admet-1437	862	2	article	article	NOUN
admet-1437	862	3	is	be	AUX
admet-1437	862	4	an	an	DET
admet-1437	862	5	open	open	ADJ
admet-1437	862	6	-	-	PUNCT
admet-1437	862	7	access	access	NOUN
admet-1437	862	8	article	article	NOUN
admet-1437	862	9	distributed	distribute	VERB
admet-1437	862	10	under	under	ADP
admet-1437	862	11	the	the	DET
admet-1437	862	12	terms	term	NOUN
admet-1437	862	13	and	and	CCONJ
admet-1437	862	14	conditions	condition	NOUN
admet-1437	862	15	of	of	ADP
admet-1437	862	16	the	the	DET
admet-1437	862	17	creative	creative	ADJ
admet-1437	862	18	commons	common	NOUN
admet-1437	862	19	attribution	attribution	NOUN
admet-1437	862	20	license	license	NOUN
admet-1437	862	21	(	(	PUNCT
admet-1437	862	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-1437	862	23	)	)	PUNCT
admet-1437	862	24	http://dx.doi.org/10.5599/admet.1437	http://dx.doi.org/10.5599/admet.1437	VERB
admet-1437	862	25	https://doi.org/10.1016/j.ejps.2021.105812	https://doi.org/10.1016/j.ejps.2021.105812	PROPN
admet-1437	862	26	https://doi.org/10.1002/jps.21650	https://doi.org/10.1002/jps.21650	NOUN
admet-1437	862	27	https://doi.org/10.1016/j.addr.2016.03.006	https://doi.org/10.1016/j.addr.2016.03.006	ADJ
admet-1437	862	28	https://doi.org/10.1016/j.addr.2016.03.006	https://doi.org/10.1016/j.addr.2016.03.006	ADJ
admet-1437	862	29	https://doi.org/10.1016/j.ejps.2019.104967	https://doi.org/10.1016/j.ejps.2019.104967	ADJ
admet-1437	862	30	https://doi.org/10.1016/j.addr.2021.02.001	https://doi.org/10.1016/j.addr.2021.02.001	PROPN
admet-1437	862	31	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-1437	862	32	)	)	PUNCT