id	sid	tid	token	lemma	pos
admet-1468	1	1	synthesis	synthesis	NOUN
admet-1468	1	2	and	and	CCONJ
admet-1468	1	3	biological	biological	ADJ
admet-1468	1	4	evaluation	evaluation	NOUN
admet-1468	1	5	of	of	ADP
admet-1468	1	6	coumarin	coumarin	NOUN
admet-1468	1	7	-	-	PUNCT
admet-1468	1	8	quinone	quinone	NOUN
admet-1468	1	9	hybrids	hybrid	NOUN
admet-1468	1	10	as	as	ADP
admet-1468	1	11	multifunctional	multifunctional	ADJ
admet-1468	1	12	bioactive	bioactive	PROPN
admet-1468	1	13	agents	agents	PROPN
admet-1468	1	14	doi	doi	PROPN
admet-1468	1	15	:	:	PUNCT
admet-1468	1	16	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NUM
admet-1468	1	17	81	81	NUM
admet-1468	1	18	admet	admet	PROPN
admet-1468	1	19	&	&	CCONJ
admet-1468	1	20	dmpk	dmpk	PROPN
admet-1468	1	21	11(1	11(1	NUM
admet-1468	1	22	)	)	PUNCT
admet-1468	1	23	(	(	PUNCT
admet-1468	1	24	2023	2023	NUM
admet-1468	1	25	)	)	PUNCT
admet-1468	1	26	81	81	NUM
admet-1468	1	27	-	-	SYM
admet-1468	1	28	96	96	NUM
admet-1468	1	29	;	;	PUNCT
admet-1468	1	30	doi	doi	NOUN
admet-1468	1	31	:	:	PUNCT
admet-1468	1	32	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	1	33	open	open	ADJ
admet-1468	1	34	access	access	NOUN
admet-1468	1	35	:	:	PUNCT
admet-1468	1	36	issn	issn	PROPN
admet-1468	1	37	:	:	PUNCT
admet-1468	1	38	1848	1848	NUM
admet-1468	1	39	-	-	SYM
admet-1468	1	40	7718	7718	NUM
admet-1468	1	41	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-1468	1	42	original	original	ADJ
admet-1468	1	43	scientific	scientific	ADJ
admet-1468	1	44	paper	paper	NOUN
admet-1468	1	45	synthesis	synthesis	NOUN
admet-1468	1	46	and	and	CCONJ
admet-1468	1	47	biological	biological	ADJ
admet-1468	1	48	evaluation	evaluation	NOUN
admet-1468	1	49	of	of	ADP
admet-1468	1	50	coumarin	coumarin	NOUN
admet-1468	1	51	-	-	PUNCT
admet-1468	1	52	quinone	quinone	NOUN
admet-1468	1	53	hybrids	hybrid	NOUN
admet-1468	1	54	as	as	ADP
admet-1468	1	55	multifunctional	multifunctional	ADJ
admet-1468	1	56	bioactive	bioactive	PROPN
admet-1468	1	57	agents	agents	PROPN
admet-1468	1	58	anees	anee	VERB
admet-1468	1	59	pangal1,2	pangal1,2	PROPN
admet-1468	1	60	and	and	CCONJ
admet-1468	1	61	khursheed	khursheed	VERB
admet-1468	1	62	ahmed1,2	ahmed1,2	PROPN
admet-1468	1	63	*	*	SYM
admet-1468	1	64	1	1	NUM
admet-1468	1	65	department	department	NOUN
admet-1468	1	66	of	of	ADP
admet-1468	1	67	chemistry	chemistry	PROPN
admet-1468	1	68	&	&	CCONJ
admet-1468	1	69	post	post	PROPN
admet-1468	1	70	graduate	graduate	PROPN
admet-1468	1	71	centre	centre	NOUN
admet-1468	1	72	,	,	PUNCT
admet-1468	1	73	abeda	abeda	PROPN
admet-1468	1	74	inamdar	inamdar	PROPN
admet-1468	1	75	sr	sr	PROPN
admet-1468	1	76	.	.	PUNCT
admet-1468	2	1	college	college	PROPN
admet-1468	2	2	of	of	ADP
admet-1468	2	3	arts	art	NOUN
admet-1468	2	4	,	,	PUNCT
admet-1468	2	5	science	science	PROPN
admet-1468	2	6	&	&	CCONJ
admet-1468	2	7	commerce	commerce	PROPN
admet-1468	2	8	(	(	PUNCT
admet-1468	2	9	autonomous	autonomous	ADJ
admet-1468	2	10	)	)	PUNCT
admet-1468	2	11	,	,	PUNCT
admet-1468	2	12	camp	camp	NOUN
admet-1468	2	13	,	,	PUNCT
admet-1468	2	14	pune	pune	NOUN
admet-1468	2	15	–	–	PUNCT
admet-1468	2	16	411001	411001	NUM
admet-1468	2	17	,	,	PUNCT
admet-1468	2	18	india	india	PROPN
admet-1468	2	19	2	2	NUM
admet-1468	2	20	advanced	advance	VERB
admet-1468	2	21	scientific	scientific	ADJ
admet-1468	2	22	research	research	NOUN
admet-1468	2	23	laboratory	laboratory	NOUN
admet-1468	2	24	,	,	PUNCT
admet-1468	2	25	azam	azam	PROPN
admet-1468	2	26	campus	campus	PROPN
admet-1468	2	27	,	,	PUNCT
admet-1468	2	28	pune	pune	NOUN
admet-1468	2	29	–	–	PUNCT
admet-1468	2	30	411001	411001	NUM
admet-1468	2	31	,	,	PUNCT
admet-1468	2	32	india	india	PROPN
admet-1468	2	33	.	.	PUNCT
admet-1468	3	1	*	*	PUNCT
admet-1468	3	2	corresponding	correspond	VERB
admet-1468	3	3	author	author	NOUN
admet-1468	3	4	:	:	PUNCT
admet-1468	3	5	e	e	NOUN
admet-1468	3	6	-	-	NOUN
admet-1468	3	7	mail	mail	NOUN
admet-1468	3	8	:	:	PUNCT
admet-1468	3	9	khursheedahmed@azamcampus.org	khursheedahmed@azamcampus.org	PROPN
admet-1468	3	10	received	receive	VERB
admet-1468	3	11	:	:	PUNCT
admet-1468	3	12	july	july	PROPN
admet-1468	3	13	22	22	NUM
admet-1468	3	14	,	,	PUNCT
admet-1468	3	15	2022	2022	NUM
admet-1468	3	16	;	;	PUNCT
admet-1468	3	17	revised	revise	VERB
admet-1468	3	18	:	:	PUNCT
admet-1468	3	19	september	september	PROPN
admet-1468	3	20	29	29	NUM
admet-1468	3	21	,	,	PUNCT
admet-1468	3	22	2022	2022	NUM
admet-1468	3	23	;	;	PUNCT
admet-1468	3	24	published	publish	VERB
admet-1468	3	25	:	:	PUNCT
admet-1468	3	26	october	october	PROPN
admet-1468	3	27	07	07	NUM
admet-1468	3	28	,	,	PUNCT
admet-1468	3	29	2022	2022	NUM
admet-1468	3	30	abstract	abstract	NOUN
admet-1468	3	31	we	we	PRON
admet-1468	3	32	report	report	VERB
admet-1468	3	33	the	the	DET
admet-1468	3	34	synthesis	synthesis	NOUN
admet-1468	3	35	,	,	PUNCT
admet-1468	3	36	structural	structural	ADJ
admet-1468	3	37	characterization	characterization	NOUN
admet-1468	3	38	and	and	CCONJ
admet-1468	3	39	pharmaceutical	pharmaceutical	NOUN
admet-1468	3	40	activity	activity	NOUN
admet-1468	3	41	of	of	ADP
admet-1468	3	42	four	four	NUM
admet-1468	3	43	coumarin	coumarin	NOUN
admet-1468	3	44	-	-	PUNCT
admet-1468	3	45	quinone	quinone	NOUN
admet-1468	3	46	hybrids	hybrid	NOUN
admet-1468	3	47	.	.	PUNCT
admet-1468	4	1	the	the	DET
admet-1468	4	2	compounds	compound	NOUN
admet-1468	4	3	were	be	AUX
admet-1468	4	4	significantly	significantly	ADV
admet-1468	4	5	active	active	ADJ
admet-1468	4	6	against	against	ADP
admet-1468	4	7	staphylococcus	staphylococcus	NOUN
admet-1468	4	8	aureus	aureus	NOUN
admet-1468	4	9	,	,	PUNCT
admet-1468	4	10	pseudomonas	pseudomona	VERB
admet-1468	4	11	aeoginosa	aeoginosa	NOUN
admet-1468	4	12	and	and	CCONJ
admet-1468	4	13	candida	candida	NOUN
admet-1468	4	14	albicans	albican	NOUN
admet-1468	4	15	.	.	PUNCT
admet-1468	5	1	promising	promise	VERB
admet-1468	5	2	antioxidant	antioxidant	ADJ
admet-1468	5	3	activity	activity	NOUN
admet-1468	5	4	was	be	AUX
admet-1468	5	5	observed	observe	VERB
admet-1468	5	6	when	when	SCONJ
admet-1468	5	7	compared	compare	VERB
admet-1468	5	8	to	to	ADP
admet-1468	5	9	ascorbic	ascorbic	NOUN
admet-1468	5	10	acid	acid	NOUN
admet-1468	5	11	.	.	PUNCT
admet-1468	6	1	two	two	NUM
admet-1468	6	2	compounds	compound	NOUN
admet-1468	6	3	,	,	PUNCT
admet-1468	6	4	dtbsb	dtbsb	NOUN
admet-1468	6	5	and	and	CCONJ
admet-1468	6	6	dtbsn	dtbsn	NOUN
admet-1468	6	7	,	,	PUNCT
admet-1468	6	8	also	also	ADV
admet-1468	6	9	showed	show	VERB
admet-1468	6	10	commendable	commendable	ADJ
admet-1468	6	11	in	in	ADP
admet-1468	6	12	vitro	vitro	X
admet-1468	6	13	antiproliferative	antiproliferative	ADJ
admet-1468	6	14	activities	activity	NOUN
admet-1468	6	15	against	against	ADP
admet-1468	6	16	the	the	DET
admet-1468	6	17	cells	cell	NOUN
admet-1468	6	18	of	of	ADP
admet-1468	6	19	human	human	ADJ
admet-1468	6	20	cancer	cancer	NOUN
admet-1468	6	21	cell	cell	NOUN
admet-1468	6	22	lines	line	NOUN
admet-1468	6	23	mcf-7	mcf-7	NOUN
admet-1468	6	24	,	,	PUNCT
admet-1468	6	25	mda	mda	PROPN
admet-1468	6	26	-	-	PUNCT
admet-1468	6	27	mb-231	mb-231	PROPN
admet-1468	6	28	,	,	PUNCT
admet-1468	6	29	colo-205	colo-205	NOUN
admet-1468	6	30	,	,	PUNCT
admet-1468	6	31	ht-29	ht-29	PUNCT
admet-1468	6	32	and	and	CCONJ
admet-1468	6	33	a549	a549	PROPN
admet-1468	6	34	along	along	ADP
admet-1468	6	35	with	with	ADP
admet-1468	6	36	appreciable	appreciable	ADJ
admet-1468	6	37	tumor	tumor	NOUN
admet-1468	6	38	selectivity	selectivity	NOUN
admet-1468	6	39	with	with	ADP
admet-1468	6	40	distinct	distinct	ADJ
admet-1468	6	41	selectivity	selectivity	NOUN
admet-1468	6	42	index	index	NOUN
admet-1468	6	43	.	.	PUNCT
admet-1468	7	1	molecular	molecular	ADJ
admet-1468	7	2	docking	docking	NOUN
admet-1468	7	3	studies	study	NOUN
admet-1468	7	4	using	use	VERB
admet-1468	7	5	cyclooxygenase-2	cyclooxygenase-2	NUM
admet-1468	7	6	(	(	PUNCT
admet-1468	7	7	pdb	pdb	PROPN
admet-1468	7	8	i	i	PROPN
admet-1468	7	9	d	d	PROPN
admet-1468	7	10	:	:	PUNCT
admet-1468	7	11	6cox	6cox	X
admet-1468	7	12	)	)	PUNCT
admet-1468	7	13	revealed	reveal	VERB
admet-1468	7	14	strong	strong	ADJ
admet-1468	7	15	binding	bind	VERB
admet-1468	7	16	affinities	affinity	NOUN
admet-1468	7	17	for	for	ADP
admet-1468	7	18	the	the	DET
admet-1468	7	19	cox-2	cox-2	ADJ
admet-1468	7	20	active	active	ADJ
admet-1468	7	21	site	site	NOUN
admet-1468	7	22	.	.	PUNCT
admet-1468	8	1	moreover	moreover	ADV
admet-1468	8	2	,	,	PUNCT
admet-1468	8	3	admet	admet	PROPN
admet-1468	8	4	properties	property	NOUN
admet-1468	8	5	of	of	ADP
admet-1468	8	6	the	the	DET
admet-1468	8	7	synthesized	synthesize	VERB
admet-1468	8	8	compounds	compound	NOUN
admet-1468	8	9	were	be	AUX
admet-1468	8	10	determined	determine	VERB
admet-1468	8	11	using	use	VERB
admet-1468	8	12	the	the	DET
admet-1468	8	13	pkcsm	pkcsm	NOUN
admet-1468	8	14	and	and	CCONJ
admet-1468	8	15	swissadme	swissadme	NOUN
admet-1468	8	16	online	online	ADJ
admet-1468	8	17	tools	tool	NOUN
admet-1468	8	18	and	and	CCONJ
admet-1468	8	19	all	all	DET
admet-1468	8	20	the	the	DET
admet-1468	8	21	compounds	compound	NOUN
admet-1468	8	22	had	have	VERB
admet-1468	8	23	accurate	accurate	ADJ
admet-1468	8	24	pharmacokinetic	pharmacokinetic	ADJ
admet-1468	8	25	profiles	profile	NOUN
admet-1468	8	26	.	.	PUNCT
admet-1468	9	1	hence	hence	ADV
admet-1468	9	2	,	,	PUNCT
admet-1468	9	3	the	the	DET
admet-1468	9	4	new	new	ADJ
admet-1468	9	5	coumarin	coumarin	NOUN
admet-1468	9	6	-	-	PUNCT
admet-1468	9	7	quinone	quinone	NOUN
admet-1468	9	8	hybrids	hybrid	NOUN
admet-1468	9	9	dtbsb	dtbsb	NOUN
admet-1468	9	10	and	and	CCONJ
admet-1468	9	11	dtbsn	dtbsn	NOUN
admet-1468	9	12	can	can	AUX
admet-1468	9	13	be	be	AUX
admet-1468	9	14	considered	consider	VERB
admet-1468	9	15	for	for	ADP
admet-1468	9	16	optimization	optimization	NOUN
admet-1468	9	17	and	and	CCONJ
admet-1468	9	18	lead	lead	VERB
admet-1468	9	19	development	development	NOUN
admet-1468	9	20	.	.	PUNCT
admet-1468	10	1	©	©	X
admet-1468	10	2	2022	2022	NUM
admet-1468	10	3	by	by	ADP
admet-1468	10	4	the	the	DET
admet-1468	10	5	authors	author	NOUN
admet-1468	10	6	.	.	PUNCT
admet-1468	11	1	this	this	DET
admet-1468	11	2	article	article	NOUN
admet-1468	11	3	is	be	AUX
admet-1468	11	4	an	an	DET
admet-1468	11	5	open	open	ADJ
admet-1468	11	6	-	-	PUNCT
admet-1468	11	7	access	access	NOUN
admet-1468	11	8	article	article	NOUN
admet-1468	11	9	distributed	distribute	VERB
admet-1468	11	10	under	under	ADP
admet-1468	11	11	the	the	DET
admet-1468	11	12	terms	term	NOUN
admet-1468	11	13	and	and	CCONJ
admet-1468	11	14	conditions	condition	NOUN
admet-1468	11	15	of	of	ADP
admet-1468	11	16	the	the	DET
admet-1468	11	17	creative	creative	ADJ
admet-1468	11	18	commons	common	NOUN
admet-1468	11	19	attribution	attribution	NOUN
admet-1468	11	20	license	license	NOUN
admet-1468	11	21	(	(	PUNCT
admet-1468	11	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-1468	11	23	)	)	PUNCT
admet-1468	11	24	.	.	PUNCT
admet-1468	12	1	keywords	keyword	NOUN
admet-1468	12	2	admet	admet	VERB
admet-1468	12	3	;	;	PUNCT
admet-1468	12	4	molecular	molecular	ADJ
admet-1468	12	5	docking	docking	NOUN
admet-1468	12	6	;	;	PUNCT
admet-1468	12	7	antiproliferative	antiproliferative	NOUN
admet-1468	12	8	;	;	PUNCT
admet-1468	12	9	antimicrobial	antimicrobial	ADJ
admet-1468	12	10	;	;	PUNCT
admet-1468	12	11	antioxidant	antioxidant	NOUN
admet-1468	12	12	;	;	PUNCT
admet-1468	12	13	drug	drug	NOUN
admet-1468	12	14	-	-	PUNCT
admet-1468	12	15	likeness	likeness	NOUN
admet-1468	12	16	introduction	introduction	NOUN
admet-1468	12	17	natural	natural	ADJ
admet-1468	12	18	and	and	CCONJ
admet-1468	12	19	synthetic	synthetic	ADJ
admet-1468	12	20	coumarins	coumarin	NOUN
admet-1468	12	21	have	have	AUX
admet-1468	12	22	gathered	gather	VERB
admet-1468	12	23	much	much	ADJ
admet-1468	12	24	attention	attention	NOUN
admet-1468	12	25	based	base	VERB
admet-1468	12	26	on	on	ADP
admet-1468	12	27	a	a	DET
admet-1468	12	28	broad	broad	ADJ
admet-1468	12	29	spectrum	spectrum	NOUN
admet-1468	12	30	of	of	ADP
admet-1468	12	31	pharmacological	pharmacological	ADJ
admet-1468	12	32	and	and	CCONJ
admet-1468	12	33	biological	biological	ADJ
admet-1468	12	34	properties	property	NOUN
admet-1468	12	35	.	.	PUNCT
admet-1468	13	1	in	in	ADP
admet-1468	13	2	the	the	DET
admet-1468	13	3	literature	literature	NOUN
admet-1468	13	4	,	,	PUNCT
admet-1468	13	5	coumarin	coumarin	NOUN
admet-1468	13	6	and	and	CCONJ
admet-1468	13	7	its	its	PRON
admet-1468	13	8	derivatives	derivative	NOUN
admet-1468	13	9	exhibit	exhibit	VERB
admet-1468	13	10	comprehensive	comprehensive	ADJ
admet-1468	13	11	biological	biological	ADJ
admet-1468	13	12	activities	activity	NOUN
admet-1468	13	13	[	[	X
admet-1468	13	14	1	1	X
admet-1468	13	15	]	]	PUNCT
admet-1468	13	16	like	like	ADP
admet-1468	13	17	anticancer	anticancer	NOUN
admet-1468	13	18	[	[	X
admet-1468	13	19	2	2	NUM
admet-1468	13	20	-	-	SYM
admet-1468	13	21	5	5	NUM
admet-1468	13	22	]	]	PUNCT
admet-1468	13	23	,	,	PUNCT
admet-1468	13	24	antioxidant	antioxidant	ADJ
admet-1468	13	25	and	and	CCONJ
admet-1468	13	26	anti	anti	ADJ
admet-1468	13	27	-	-	ADJ
admet-1468	13	28	inflammatory	inflammatory	ADJ
admet-1468	13	29	[	[	X
admet-1468	13	30	6	6	NUM
admet-1468	13	31	]	]	PUNCT
admet-1468	13	32	,	,	PUNCT
admet-1468	13	33	antimicrobial	antimicrobial	ADJ
admet-1468	13	34	[	[	X
admet-1468	13	35	7	7	NUM
admet-1468	13	36	]	]	PUNCT
admet-1468	13	37	,	,	PUNCT
admet-1468	13	38	antifungal	antifungal	PROPN
admet-1468	14	1	[	[	X
admet-1468	14	2	8	8	NUM
admet-1468	14	3	]	]	PUNCT
admet-1468	14	4	and	and	CCONJ
admet-1468	14	5	anti	anti	PROPN
admet-1468	14	6	-	-	NOUN
admet-1468	14	7	hiv	hiv	NOUN
admet-1468	14	8	[	[	X
admet-1468	14	9	9	9	NUM
admet-1468	14	10	]	]	PUNCT
admet-1468	14	11	activities	activity	NOUN
admet-1468	14	12	.	.	PUNCT
admet-1468	15	1	natural	natural	ADJ
admet-1468	15	2	and	and	CCONJ
admet-1468	15	3	synthetic	synthetic	ADJ
admet-1468	15	4	coumarin	coumarin	NOUN
admet-1468	15	5	compounds	compound	VERB
admet-1468	15	6	like	like	ADP
admet-1468	15	7	esculetin	esculetin	NOUN
admet-1468	15	8	and	and	CCONJ
admet-1468	15	9	scopoletin	scopoletin	PROPN
admet-1468	15	10	have	have	VERB
admet-1468	15	11	potential	potential	NOUN
admet-1468	15	12	as	as	ADP
admet-1468	15	13	anticancer	anticancer	NOUN
admet-1468	15	14	agents	agent	NOUN
admet-1468	15	15	.	.	PUNCT
admet-1468	16	1	naturally	naturally	ADV
admet-1468	16	2	,	,	PUNCT
admet-1468	16	3	coumarin	coumarin	NOUN
admet-1468	16	4	displayed	display	VERB
admet-1468	16	5	antiproliferative	antiproliferative	ADJ
admet-1468	16	6	effects	effect	NOUN
admet-1468	16	7	on	on	ADP
admet-1468	16	8	various	various	ADJ
admet-1468	16	9	types	type	NOUN
admet-1468	16	10	of	of	ADP
admet-1468	16	11	cancers	cancer	NOUN
admet-1468	16	12	such	such	ADJ
admet-1468	16	13	as	as	ADP
admet-1468	16	14	prostate	prostate	NOUN
admet-1468	16	15	,	,	PUNCT
admet-1468	16	16	renal	renal	ADJ
admet-1468	16	17	,	,	PUNCT
admet-1468	16	18	breast	breast	NOUN
admet-1468	16	19	,	,	PUNCT
admet-1468	16	20	laryngeal	laryngeal	NOUN
admet-1468	16	21	,	,	PUNCT
admet-1468	16	22	lung	lung	NOUN
admet-1468	16	23	,	,	PUNCT
admet-1468	16	24	colon	colon	NOUN
admet-1468	16	25	,	,	PUNCT
admet-1468	16	26	cns	cns	NOUN
admet-1468	16	27	,	,	PUNCT
admet-1468	16	28	leukemia	leukemia	NOUN
admet-1468	16	29	and	and	CCONJ
admet-1468	16	30	melanoma	melanoma	NOUN
admet-1468	17	1	[	[	X
admet-1468	17	2	10	10	NUM
admet-1468	17	3	-	-	SYM
admet-1468	17	4	11	11	NUM
admet-1468	17	5	]	]	PUNCT
admet-1468	17	6	.	.	PUNCT
admet-1468	18	1	coumarins	coumarin	NOUN
admet-1468	18	2	are	be	AUX
admet-1468	18	3	used	use	VERB
admet-1468	18	4	in	in	ADP
admet-1468	18	5	the	the	DET
admet-1468	18	6	treatment	treatment	NOUN
admet-1468	18	7	of	of	ADP
admet-1468	18	8	different	different	ADJ
admet-1468	18	9	types	type	NOUN
admet-1468	18	10	of	of	ADP
admet-1468	18	11	cancers	cancer	NOUN
admet-1468	18	12	like	like	ADP
admet-1468	18	13	prostate	prostate	NOUN
admet-1468	18	14	cancer	cancer	NOUN
admet-1468	18	15	,	,	PUNCT
admet-1468	18	16	renal	renal	ADJ
admet-1468	18	17	cell	cell	NOUN
admet-1468	18	18	carcinoma	carcinoma	NOUN
admet-1468	18	19	and	and	CCONJ
admet-1468	18	20	leukemia	leukemia	NOUN
admet-1468	18	21	and	and	CCONJ
admet-1468	18	22	to	to	PART
admet-1468	18	23	inhibit	inhibit	VERB
admet-1468	18	24	the	the	DET
admet-1468	18	25	spread	spread	NOUN
admet-1468	18	26	of	of	ADP
admet-1468	18	27	tumors	tumor	NOUN
admet-1468	19	1	[	[	X
admet-1468	19	2	12	12	NUM
admet-1468	19	3	]	]	PUNCT
admet-1468	19	4	.	.	PUNCT
admet-1468	20	1	the	the	DET
admet-1468	20	2	wide	wide	ADJ
admet-1468	20	3	scope	scope	NOUN
admet-1468	20	4	of	of	ADP
admet-1468	20	5	biological	biological	ADJ
admet-1468	20	6	activities	activity	NOUN
admet-1468	20	7	attributed	attribute	VERB
admet-1468	20	8	to	to	ADP
admet-1468	20	9	coumarins	coumarin	NOUN
admet-1468	20	10	and	and	CCONJ
admet-1468	20	11	their	their	PRON
admet-1468	20	12	medicinal	medicinal	ADJ
admet-1468	20	13	impact	impact	NOUN
admet-1468	20	14	on	on	ADP
admet-1468	20	15	various	various	ADJ
admet-1468	20	16	disorders	disorder	NOUN
admet-1468	20	17	have	have	AUX
admet-1468	20	18	received	receive	VERB
admet-1468	20	19	considerable	considerable	ADJ
admet-1468	20	20	attention	attention	NOUN
admet-1468	20	21	.	.	PUNCT
admet-1468	21	1	furthermore	furthermore	ADV
admet-1468	21	2	,	,	PUNCT
admet-1468	21	3	the	the	DET
admet-1468	21	4	stability	stability	NOUN
admet-1468	21	5	and	and	CCONJ
admet-1468	21	6	solubility	solubility	NOUN
admet-1468	21	7	of	of	ADP
admet-1468	21	8	coumarins	coumarin	NOUN
admet-1468	21	9	are	be	AUX
admet-1468	21	10	intriguing	intriguing	ADJ
admet-1468	21	11	,	,	PUNCT
admet-1468	21	12	which	which	PRON
admet-1468	21	13	are	be	AUX
admet-1468	21	14	important	important	ADJ
admet-1468	21	15	criteria	criterion	NOUN
admet-1468	21	16	for	for	ADP
admet-1468	21	17	drug	drug	NOUN
admet-1468	21	18	development	development	NOUN
admet-1468	21	19	[	[	X
admet-1468	21	20	13	13	NUM
admet-1468	21	21	]	]	PUNCT
admet-1468	21	22	.	.	PUNCT
admet-1468	22	1	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NUM
admet-1468	22	2	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	22	3	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-1468	22	4	mailto:khursheedahmed@azamcampus.org	mailto:khursheedahmed@azamcampus.org	PROPN
admet-1468	22	5	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-1468	22	6	a.	a.	PROPN
admet-1468	22	7	pangal	pangal	PROPN
admet-1468	22	8	and	and	CCONJ
admet-1468	22	9	k.	k.	PROPN
admet-1468	22	10	ahmed	ahmed	PROPN
admet-1468	22	11	admet	admet	PROPN
admet-1468	22	12	&	&	CCONJ
admet-1468	22	13	dmpk	dmpk	PROPN
admet-1468	22	14	11(1	11(1	NUM
admet-1468	22	15	)	)	PUNCT
admet-1468	22	16	(	(	PUNCT
admet-1468	22	17	2023	2023	NUM
admet-1468	22	18	)	)	PUNCT
admet-1468	22	19	81	81	NUM
admet-1468	22	20	-	-	SYM
admet-1468	22	21	96	96	NUM
admet-1468	22	22	82	82	NUM
admet-1468	22	23	natural	natural	ADJ
admet-1468	22	24	quinones	quinone	NOUN
admet-1468	22	25	such	such	ADJ
admet-1468	22	26	as	as	ADP
admet-1468	22	27	juglone	juglone	NOUN
admet-1468	22	28	and	and	CCONJ
admet-1468	22	29	plumbagin	plumbagin	NOUN
admet-1468	22	30	exhibited	exhibit	VERB
admet-1468	22	31	growth	growth	NOUN
admet-1468	22	32	inhibitory	inhibitory	ADJ
admet-1468	22	33	effects	effect	NOUN
admet-1468	22	34	on	on	ADP
admet-1468	22	35	microorganisms	microorganism	NOUN
admet-1468	22	36	[	[	X
admet-1468	22	37	14	14	NUM
admet-1468	22	38	]	]	PUNCT
admet-1468	22	39	.	.	PUNCT
admet-1468	23	1	benzoquinones	benzoquinone	NOUN
admet-1468	23	2	play	play	VERB
admet-1468	23	3	an	an	DET
admet-1468	23	4	important	important	ADJ
admet-1468	23	5	role	role	NOUN
admet-1468	23	6	in	in	ADP
admet-1468	23	7	oxidative	oxidative	ADJ
admet-1468	23	8	phosphorylation	phosphorylation	NOUN
admet-1468	23	9	electron	electron	NOUN
admet-1468	23	10	transfer	transfer	NOUN
admet-1468	23	11	processes	process	NOUN
admet-1468	23	12	and	and	CCONJ
admet-1468	23	13	bioenergetic	bioenergetic	ADJ
admet-1468	23	14	transport	transport	NOUN
admet-1468	23	15	[	[	X
admet-1468	23	16	15	15	NUM
admet-1468	23	17	]	]	PUNCT
admet-1468	23	18	.	.	PUNCT
admet-1468	24	1	quinones	quinone	NOUN
admet-1468	24	2	showed	show	VERB
admet-1468	24	3	diverse	diverse	ADJ
admet-1468	24	4	pharmacological	pharmacological	ADJ
admet-1468	24	5	properties	property	NOUN
admet-1468	24	6	such	such	ADJ
admet-1468	24	7	as	as	ADP
admet-1468	24	8	anti	anti	ADJ
admet-1468	24	9	-	-	ADJ
admet-1468	24	10	inflammatory	inflammatory	ADJ
admet-1468	24	11	[	[	X
admet-1468	24	12	16	16	NUM
admet-1468	24	13	]	]	PUNCT
admet-1468	24	14	,	,	PUNCT
admet-1468	24	15	antimicrobial	antimicrobial	ADJ
admet-1468	24	16	[	[	X
admet-1468	24	17	17	17	NUM
admet-1468	24	18	]	]	PUNCT
admet-1468	24	19	and	and	CCONJ
admet-1468	24	20	anticancer	anticancer	NOUN
admet-1468	24	21	[	[	PUNCT
admet-1468	24	22	18	18	NUM
admet-1468	24	23	-	-	SYM
admet-1468	24	24	20	20	NUM
admet-1468	24	25	]	]	PUNCT
admet-1468	24	26	.	.	PUNCT
admet-1468	25	1	1,4	1,4	PROPN
admet-1468	25	2	-	-	PUNCT
admet-1468	25	3	benzoquinone	benzoquinone	NOUN
admet-1468	25	4	derivatives	derivative	NOUN
admet-1468	25	5	were	be	AUX
admet-1468	25	6	applied	apply	VERB
admet-1468	25	7	as	as	ADP
admet-1468	25	8	antibiotics	antibiotic	NOUN
admet-1468	25	9	[	[	X
admet-1468	25	10	2122	2122	NUM
admet-1468	25	11	]	]	PUNCT
admet-1468	25	12	,	,	PUNCT
admet-1468	25	13	antitumor	antitumor	PROPN
admet-1468	26	1	[	[	X
admet-1468	26	2	23	23	NUM
admet-1468	26	3	-	-	SYM
admet-1468	26	4	25	25	NUM
admet-1468	26	5	]	]	PUNCT
admet-1468	26	6	,	,	PUNCT
admet-1468	26	7	antimalarial	antimalarial	ADJ
admet-1468	26	8	[	[	X
admet-1468	26	9	26	26	NUM
admet-1468	26	10	]	]	PUNCT
admet-1468	26	11	and	and	CCONJ
admet-1468	26	12	anticoagulant	anticoagulant	ADJ
admet-1468	26	13	compounds	compound	NOUN
admet-1468	26	14	[	[	X
admet-1468	26	15	27	27	NUM
admet-1468	26	16	]	]	PUNCT
admet-1468	26	17	.	.	PUNCT
admet-1468	27	1	the	the	DET
admet-1468	27	2	anticancer	anticancer	NOUN
admet-1468	27	3	properties	property	NOUN
admet-1468	27	4	of	of	ADP
admet-1468	27	5	quinones	quinone	NOUN
admet-1468	27	6	are	be	AUX
admet-1468	27	7	well	well	ADV
admet-1468	27	8	described	describe	VERB
admet-1468	27	9	and	and	CCONJ
admet-1468	27	10	there	there	PRON
admet-1468	27	11	are	be	VERB
admet-1468	27	12	several	several	ADJ
admet-1468	27	13	clinically	clinically	ADV
admet-1468	27	14	important	important	ADJ
admet-1468	27	15	antitumor	antitumor	PROPN
admet-1468	27	16	drugs	drug	NOUN
admet-1468	27	17	based	base	VERB
admet-1468	27	18	on	on	ADP
admet-1468	27	19	quinone	quinone	NOUN
admet-1468	27	20	scaffolds	scaffold	NOUN
admet-1468	27	21	,	,	PUNCT
admet-1468	27	22	e.g.	e.g.	ADV
admet-1468	27	23	,	,	PUNCT
admet-1468	27	24	anthracyclines	anthracycline	NOUN
admet-1468	27	25	,	,	PUNCT
admet-1468	27	26	mitoxantrones	mitoxantrone	NOUN
admet-1468	27	27	and	and	CCONJ
admet-1468	27	28	saintopin	saintopin	NOUN
admet-1468	27	29	[	[	X
admet-1468	27	30	28	28	NUM
admet-1468	27	31	]	]	PUNCT
admet-1468	27	32	.	.	PUNCT
admet-1468	28	1	cheminformatic	cheminformatic	ADJ
admet-1468	28	2	tools	tool	NOUN
admet-1468	28	3	,	,	PUNCT
admet-1468	28	4	including	include	VERB
admet-1468	28	5	the	the	DET
admet-1468	28	6	prediction	prediction	NOUN
admet-1468	28	7	of	of	ADP
admet-1468	28	8	activity	activity	NOUN
admet-1468	28	9	spectra	spectra	NOUN
admet-1468	28	10	for	for	ADP
admet-1468	28	11	substances	substance	NOUN
admet-1468	28	12	(	(	PUNCT
admet-1468	28	13	pass	pass	NOUN
admet-1468	28	14	)	)	PUNCT
admet-1468	28	15	,	,	PUNCT
admet-1468	28	16	lipinski	lipinski	PROPN
admet-1468	28	17	’s	’s	PART
admet-1468	28	18	rule	rule	NOUN
admet-1468	28	19	of	of	ADP
admet-1468	28	20	five	five	NUM
admet-1468	28	21	,	,	PUNCT
admet-1468	28	22	and	and	CCONJ
admet-1468	28	23	admet	admet	PROPN
admet-1468	28	24	(	(	PUNCT
admet-1468	28	25	absorption	absorption	NOUN
admet-1468	28	26	,	,	PUNCT
admet-1468	28	27	distribution	distribution	NOUN
admet-1468	28	28	,	,	PUNCT
admet-1468	28	29	metabolism	metabolism	NOUN
admet-1468	28	30	,	,	PUNCT
admet-1468	28	31	and	and	CCONJ
admet-1468	28	32	excretion	excretion	NOUN
admet-1468	28	33	–	–	PUNCT
admet-1468	28	34	toxicity	toxicity	NOUN
admet-1468	28	35	)	)	PUNCT
admet-1468	28	36	predictions	prediction	NOUN
admet-1468	28	37	,	,	PUNCT
admet-1468	28	38	are	be	AUX
admet-1468	28	39	useful	useful	ADJ
admet-1468	28	40	applications	application	NOUN
admet-1468	28	41	for	for	ADP
admet-1468	28	42	the	the	DET
admet-1468	28	43	optimization	optimization	NOUN
admet-1468	28	44	of	of	ADP
admet-1468	28	45	drug	drug	NOUN
admet-1468	28	46	discovery	discovery	NOUN
admet-1468	28	47	[	[	X
admet-1468	28	48	29	29	NUM
admet-1468	28	49	]	]	PUNCT
admet-1468	28	50	.	.	PUNCT
admet-1468	29	1	admet	admet	PROPN
admet-1468	29	2	,	,	PUNCT
admet-1468	29	3	which	which	PRON
admet-1468	29	4	constitutes	constitute	VERB
admet-1468	29	5	the	the	DET
admet-1468	29	6	pharmacokinetic	pharmacokinetic	ADJ
admet-1468	29	7	profile	profile	NOUN
admet-1468	29	8	of	of	ADP
admet-1468	29	9	a	a	DET
admet-1468	29	10	drug	drug	NOUN
admet-1468	29	11	molecule	molecule	NOUN
admet-1468	29	12	,	,	PUNCT
admet-1468	29	13	is	be	AUX
admet-1468	29	14	essential	essential	ADJ
admet-1468	29	15	for	for	ADP
admet-1468	29	16	the	the	DET
admet-1468	29	17	evaluation	evaluation	NOUN
admet-1468	29	18	of	of	ADP
admet-1468	29	19	its	its	PRON
admet-1468	29	20	pharmacodynamic	pharmacodynamic	ADJ
admet-1468	29	21	properties	property	NOUN
admet-1468	29	22	[	[	X
admet-1468	29	23	30	30	NUM
admet-1468	29	24	]	]	PUNCT
admet-1468	29	25	.	.	PUNCT
admet-1468	30	1	admet	admet	PROPN
admet-1468	30	2	predictor	predictor	PROPN
admet-1468	30	3	is	be	AUX
admet-1468	30	4	a	a	DET
admet-1468	30	5	program	program	NOUN
admet-1468	30	6	designed	design	VERB
admet-1468	30	7	for	for	ADP
admet-1468	30	8	the	the	DET
admet-1468	30	9	estimation	estimation	NOUN
admet-1468	30	10	of	of	ADP
admet-1468	30	11	pharmacokinetic	pharmacokinetic	ADJ
admet-1468	30	12	parameters	parameter	NOUN
admet-1468	30	13	or	or	CCONJ
admet-1468	30	14	properties	property	NOUN
admet-1468	30	15	based	base	VERB
admet-1468	30	16	on	on	ADP
admet-1468	30	17	molecular	molecular	ADJ
admet-1468	30	18	structures	structure	NOUN
admet-1468	30	19	of	of	ADP
admet-1468	30	20	drug	drug	NOUN
admet-1468	30	21	candidates	candidate	NOUN
admet-1468	30	22	[	[	X
admet-1468	30	23	31	31	NUM
admet-1468	30	24	]	]	PUNCT
admet-1468	30	25	.	.	PUNCT
admet-1468	31	1	the	the	DET
admet-1468	31	2	ideal	ideal	ADJ
admet-1468	31	3	oral	oral	ADJ
admet-1468	31	4	drug	drug	NOUN
admet-1468	31	5	is	be	AUX
admet-1468	31	6	rapidly	rapidly	ADV
admet-1468	31	7	and	and	CCONJ
admet-1468	31	8	completely	completely	ADV
admet-1468	31	9	absorbed	absorb	VERB
admet-1468	31	10	by	by	ADP
admet-1468	31	11	the	the	DET
admet-1468	31	12	gastrointestinal	gastrointestinal	ADJ
admet-1468	31	13	tract	tract	NOUN
admet-1468	31	14	,	,	PUNCT
admet-1468	31	15	is	be	AUX
admet-1468	31	16	distributed	distribute	VERB
admet-1468	31	17	specifically	specifically	ADV
admet-1468	31	18	to	to	ADP
admet-1468	31	19	its	its	PRON
admet-1468	31	20	site	site	NOUN
admet-1468	31	21	of	of	ADP
admet-1468	31	22	action	action	NOUN
admet-1468	31	23	in	in	ADP
admet-1468	31	24	the	the	DET
admet-1468	31	25	body	body	NOUN
admet-1468	31	26	,	,	PUNCT
admet-1468	31	27	is	be	AUX
admet-1468	31	28	metabolized	metabolize	VERB
admet-1468	31	29	in	in	ADP
admet-1468	31	30	a	a	DET
admet-1468	31	31	way	way	NOUN
admet-1468	31	32	that	that	PRON
admet-1468	31	33	does	do	AUX
admet-1468	31	34	not	not	PART
admet-1468	31	35	instantly	instantly	ADV
admet-1468	31	36	diminish	diminish	VERB
admet-1468	31	37	its	its	PRON
admet-1468	31	38	activity	activity	NOUN
admet-1468	31	39	,	,	PUNCT
admet-1468	31	40	and	and	CCONJ
admet-1468	31	41	is	be	AUX
admet-1468	31	42	eliminated	eliminate	VERB
admet-1468	31	43	without	without	ADP
admet-1468	31	44	causing	cause	VERB
admet-1468	31	45	harm	harm	NOUN
admet-1468	31	46	.	.	PUNCT
admet-1468	32	1	therefore	therefore	ADV
admet-1468	32	2	,	,	PUNCT
admet-1468	32	3	admet	admet	PROPN
admet-1468	32	4	properties	property	NOUN
admet-1468	32	5	are	be	AUX
admet-1468	32	6	important	important	ADJ
admet-1468	32	7	determinants	determinant	NOUN
admet-1468	32	8	of	of	ADP
admet-1468	32	9	the	the	DET
admet-1468	32	10	test	test	NOUN
admet-1468	32	11	compound	compound	NOUN
admet-1468	32	12	for	for	ADP
admet-1468	32	13	any	any	DET
admet-1468	32	14	future	future	ADJ
admet-1468	32	15	therapeutic	therapeutic	ADJ
admet-1468	32	16	application	application	NOUN
admet-1468	32	17	in	in	ADP
admet-1468	32	18	humans	human	NOUN
admet-1468	32	19	[	[	X
admet-1468	32	20	32	32	NUM
admet-1468	32	21	]	]	PUNCT
admet-1468	32	22	.	.	PUNCT
admet-1468	33	1	in	in	ADP
admet-1468	33	2	this	this	DET
admet-1468	33	3	work	work	NOUN
admet-1468	33	4	,	,	PUNCT
admet-1468	33	5	we	we	PRON
admet-1468	33	6	combined	combine	VERB
admet-1468	33	7	coumarin	coumarin	NOUN
admet-1468	33	8	and	and	CCONJ
admet-1468	33	9	quinone	quinone	NOUN
admet-1468	33	10	moieties	moiety	NOUN
admet-1468	33	11	to	to	PART
admet-1468	33	12	obtain	obtain	VERB
admet-1468	33	13	new	new	ADJ
admet-1468	33	14	hybrid	hybrid	ADJ
admet-1468	33	15	molecules	molecule	NOUN
admet-1468	33	16	with	with	ADP
admet-1468	33	17	promising	promising	ADJ
admet-1468	33	18	biological	biological	ADJ
admet-1468	33	19	activities	activity	NOUN
admet-1468	33	20	such	such	ADJ
admet-1468	33	21	as	as	ADP
admet-1468	33	22	antimicrobial	antimicrobial	ADJ
admet-1468	33	23	,	,	PUNCT
admet-1468	33	24	antioxidant	antioxidant	ADJ
admet-1468	33	25	and	and	CCONJ
admet-1468	33	26	anticancer	anticancer	NOUN
admet-1468	33	27	properties	property	NOUN
admet-1468	33	28	.	.	PUNCT
admet-1468	34	1	the	the	DET
admet-1468	34	2	interaction	interaction	NOUN
admet-1468	34	3	and	and	CCONJ
admet-1468	34	4	binding	bind	VERB
admet-1468	34	5	affinities	affinity	NOUN
admet-1468	34	6	of	of	ADP
admet-1468	34	7	the	the	DET
admet-1468	34	8	new	new	ADJ
admet-1468	34	9	test	test	NOUN
admet-1468	34	10	compounds	compound	VERB
admet-1468	34	11	with	with	ADP
admet-1468	34	12	cyclooxygenase	cyclooxygenase	PROPN
admet-1468	34	13	(	(	PUNCT
admet-1468	34	14	cox	cox	PROPN
admet-1468	34	15	)	)	PUNCT
admet-1468	34	16	were	be	AUX
admet-1468	34	17	determined	determine	VERB
admet-1468	34	18	via	via	ADP
admet-1468	34	19	docking	docking	NOUN
admet-1468	34	20	calculations	calculation	NOUN
admet-1468	34	21	.	.	PUNCT
admet-1468	35	1	the	the	DET
admet-1468	35	2	drug	drug	NOUN
admet-1468	35	3	-	-	PUNCT
admet-1468	35	4	like	like	ADJ
admet-1468	35	5	potential	potential	NOUN
admet-1468	35	6	of	of	ADP
admet-1468	35	7	these	these	DET
admet-1468	35	8	hybrids	hybrid	NOUN
admet-1468	35	9	was	be	AUX
admet-1468	35	10	evaluated	evaluate	VERB
admet-1468	35	11	using	use	VERB
admet-1468	35	12	in	in	ADP
admet-1468	35	13	silico	silico	NOUN
admet-1468	35	14	methods	method	NOUN
admet-1468	35	15	.	.	PUNCT
admet-1468	36	1	of	of	ADP
admet-1468	36	2	the	the	DET
admet-1468	36	3	four	four	NUM
admet-1468	36	4	synthesized	synthesize	VERB
admet-1468	36	5	coumarin	coumarin	NOUN
admet-1468	36	6	-	-	PUNCT
admet-1468	36	7	quinone	quinone	NOUN
admet-1468	36	8	hybrids	hybrid	NOUN
admet-1468	36	9	,	,	PUNCT
admet-1468	36	10	dtbsb	dtbsb	NOUN
admet-1468	36	11	and	and	CCONJ
admet-1468	36	12	dtbsn	dtbsn	NOUN
admet-1468	36	13	were	be	AUX
admet-1468	36	14	found	find	VERB
admet-1468	36	15	to	to	PART
admet-1468	36	16	be	be	AUX
admet-1468	36	17	more	more	ADV
admet-1468	36	18	effective	effective	ADJ
admet-1468	36	19	biological	biological	ADJ
admet-1468	36	20	agents	agent	NOUN
admet-1468	36	21	among	among	ADP
admet-1468	36	22	the	the	DET
admet-1468	36	23	synthesized	synthesize	VERB
admet-1468	36	24	analogs	analog	NOUN
admet-1468	36	25	.	.	PUNCT
admet-1468	37	1	experimental	experimental	ADJ
admet-1468	37	2	materials	material	NOUN
admet-1468	37	3	solvents	solvent	NOUN
admet-1468	37	4	were	be	AUX
admet-1468	37	5	purchased	purchase	VERB
admet-1468	37	6	from	from	ADP
admet-1468	37	7	commercial	commercial	ADJ
admet-1468	37	8	sources	source	NOUN
admet-1468	37	9	and	and	CCONJ
admet-1468	37	10	were	be	AUX
admet-1468	37	11	dried	dry	VERB
admet-1468	37	12	by	by	ADP
admet-1468	37	13	standard	standard	ADJ
admet-1468	37	14	protocols	protocol	NOUN
admet-1468	37	15	.	.	PUNCT
admet-1468	38	1	the	the	DET
admet-1468	38	2	starting	start	VERB
admet-1468	38	3	materials	material	NOUN
admet-1468	38	4	such	such	ADJ
admet-1468	38	5	as	as	ADP
admet-1468	38	6	ethyl	ethyl	PROPN
admet-1468	38	7	3	3	PROPN
admet-1468	38	8	-	-	PUNCT
admet-1468	38	9	hydrazinyl-3	hydrazinyl-3	NOUN
admet-1468	38	10	-	-	PUNCT
admet-1468	38	11	oxopropanoate	oxopropanoate	NOUN
admet-1468	38	12	,	,	PUNCT
admet-1468	38	13	2,6	2,6	NUM
admet-1468	38	14	-	-	ADJ
admet-1468	38	15	di	di	NOUN
admet-1468	38	16	-	-	PUNCT
admet-1468	38	17	tert	tert	NOUN
admet-1468	38	18	-	-	PUNCT
admet-1468	38	19	butyl-1,4	butyl-1,4	NOUN
admet-1468	38	20	-	-	PUNCT
admet-1468	38	21	benzoquinone	benzoquinone	NOUN
admet-1468	38	22	,	,	PUNCT
admet-1468	38	23	5bromosalicylaldehyde	5bromosalicylaldehyde	NUM
admet-1468	38	24	,	,	PUNCT
admet-1468	38	25	5	5	NUM
admet-1468	38	26	-	-	PUNCT
admet-1468	38	27	chlorosalicylaldehyde	chlorosalicylaldehyde	NOUN
admet-1468	38	28	,	,	PUNCT
admet-1468	38	29	and	and	CCONJ
admet-1468	38	30	5	5	NUM
admet-1468	38	31	-	-	PUNCT
admet-1468	38	32	nitrosalicylaldehyde	nitrosalicylaldehyde	NOUN
admet-1468	38	33	were	be	AUX
admet-1468	38	34	obtained	obtain	VERB
admet-1468	38	35	from	from	ADP
admet-1468	38	36	sigmaaldrich	sigmaaldrich	PROPN
admet-1468	38	37	,	,	PUNCT
admet-1468	38	38	india	india	PROPN
admet-1468	38	39	.	.	PUNCT
admet-1468	39	1	salicylaldehyde	salicylaldehyde	PROPN
admet-1468	39	2	,	,	PUNCT
admet-1468	39	3	trifluoroacetic	trifluoroacetic	ADJ
admet-1468	39	4	acid	acid	NOUN
admet-1468	39	5	,	,	PUNCT
admet-1468	39	6	piperidine	piperidine	NOUN
admet-1468	39	7	,	,	PUNCT
admet-1468	39	8	acetone	acetone	NOUN
admet-1468	39	9	,	,	PUNCT
admet-1468	39	10	methanol	methanol	NOUN
admet-1468	39	11	,	,	PUNCT
admet-1468	39	12	ethanol	ethanol	NOUN
admet-1468	39	13	and	and	CCONJ
admet-1468	39	14	dichloromethane	dichloromethane	NOUN
admet-1468	39	15	were	be	AUX
admet-1468	39	16	obtained	obtain	VERB
admet-1468	39	17	from	from	ADP
admet-1468	39	18	sd	sd	NOUN
admet-1468	39	19	-	-	PUNCT
admet-1468	39	20	fcl	fcl	ADJ
admet-1468	39	21	chemical	chemical	NOUN
admet-1468	39	22	limited	limited	ADJ
admet-1468	39	23	,	,	PUNCT
admet-1468	39	24	mumbai	mumbai	PROPN
admet-1468	39	25	,	,	PUNCT
admet-1468	39	26	india	india	PROPN
admet-1468	39	27	.	.	PROPN
admet-1468	40	1	dmem	dmem	PROPN
admet-1468	40	2	and	and	CCONJ
admet-1468	40	3	fbs	fbs	PROPN
admet-1468	40	4	were	be	AUX
admet-1468	40	5	purchased	purchase	VERB
admet-1468	40	6	from	from	ADP
admet-1468	40	7	himedia	himedia	NOUN
admet-1468	40	8	,	,	PUNCT
admet-1468	40	9	mumbai	mumbai	PROPN
admet-1468	40	10	.	.	PUNCT
admet-1468	41	1	the	the	DET
admet-1468	41	2	mtt	mtt	NOUN
admet-1468	41	3	(	(	PUNCT
admet-1468	41	4	3-(4,5	3-(4,5	PROPN
admet-1468	41	5	-	-	PUNCT
admet-1468	41	6	dimethyl-2	dimethyl-2	PROPN
admet-1468	41	7	-	-	PUNCT
admet-1468	41	8	thiazolyl)-2,5	thiazolyl)-2,5	ADP
admet-1468	41	9	-	-	PUNCT
admet-1468	41	10	diphenyl-2h	diphenyl-2h	NOUN
admet-1468	41	11	-	-	PUNCT
admet-1468	41	12	tetrazolium	tetrazolium	NOUN
admet-1468	41	13	bromide	bromide	NOUN
admet-1468	41	14	)	)	PUNCT
admet-1468	41	15	reagent	reagent	NOUN
admet-1468	41	16	was	be	AUX
admet-1468	41	17	obtained	obtain	VERB
admet-1468	41	18	from	from	ADP
admet-1468	41	19	g	g	NOUN
admet-1468	41	20	-	-	PUNCT
admet-1468	41	21	biosciences	bioscience	NOUN
admet-1468	41	22	,	,	PUNCT
admet-1468	41	23	usa	usa	PROPN
admet-1468	41	24	.	.	PROPN
admet-1468	41	25	tlc	tlc	PROPN
admet-1468	41	26	was	be	AUX
admet-1468	41	27	monitored	monitor	VERB
admet-1468	41	28	using	use	VERB
admet-1468	41	29	commercially	commercially	ADV
admet-1468	41	30	available	available	ADJ
admet-1468	41	31	aluminium	aluminium	NOUN
admet-1468	41	32	tlc	tlc	NOUN
admet-1468	41	33	plates	plate	NOUN
admet-1468	41	34	coated	coat	VERB
admet-1468	41	35	with	with	ADP
admet-1468	41	36	silica	silica	NOUN
admet-1468	41	37	gel	gel	NOUN
admet-1468	41	38	gf254	gf254	PROPN
admet-1468	41	39	,	,	PUNCT
admet-1468	41	40	and	and	CCONJ
admet-1468	41	41	the	the	DET
admet-1468	41	42	developed	develop	VERB
admet-1468	41	43	plates	plate	NOUN
admet-1468	41	44	were	be	AUX
admet-1468	41	45	visualized	visualize	VERB
admet-1468	41	46	by	by	ADP
admet-1468	41	47	uv	uv	NOUN
admet-1468	41	48	light	light	NOUN
admet-1468	41	49	and	and	CCONJ
admet-1468	41	50	iodine	iodine	NOUN
admet-1468	41	51	vapors	vapor	NOUN
admet-1468	41	52	.	.	PUNCT
admet-1468	42	1	melting	melt	VERB
admet-1468	42	2	points	point	NOUN
admet-1468	42	3	of	of	ADP
admet-1468	42	4	synthesized	synthesize	VERB
admet-1468	42	5	compounds	compound	NOUN
admet-1468	42	6	were	be	AUX
admet-1468	42	7	determined	determine	VERB
admet-1468	42	8	with	with	ADP
admet-1468	42	9	an	an	DET
admet-1468	42	10	open	open	ADJ
admet-1468	42	11	capillary	capillary	ADJ
admet-1468	42	12	tube	tube	NOUN
admet-1468	42	13	using	use	VERB
admet-1468	42	14	a	a	DET
admet-1468	42	15	veego	veego	ADJ
admet-1468	42	16	melting	melting	NOUN
admet-1468	42	17	point	point	NOUN
admet-1468	42	18	apparatus	apparatus	NOUN
admet-1468	42	19	.	.	PUNCT
admet-1468	43	1	the	the	DET
admet-1468	43	2	hrms	hrm	NOUN
admet-1468	43	3	,	,	PUNCT
admet-1468	43	4	ftir	ftir	NOUN
admet-1468	43	5	and	and	CCONJ
admet-1468	43	6	nmr	nmr	NOUN
admet-1468	43	7	spectroscopic	spectroscopic	ADJ
admet-1468	43	8	data	datum	NOUN
admet-1468	43	9	were	be	AUX
admet-1468	43	10	obtained	obtain	VERB
admet-1468	43	11	from	from	ADP
admet-1468	43	12	cif	cif	PROPN
admet-1468	43	13	,	,	PUNCT
admet-1468	43	14	savitribai	savitribai	PROPN
admet-1468	43	15	phule	phule	PROPN
admet-1468	43	16	pune	pune	PROPN
admet-1468	43	17	university	university	PROPN
admet-1468	43	18	,	,	PUNCT
admet-1468	43	19	pune	pune	NOUN
admet-1468	43	20	and	and	CCONJ
admet-1468	43	21	cif	cif	PROPN
admet-1468	43	22	,	,	PUNCT
admet-1468	43	23	iisc	iisc	NOUN
admet-1468	43	24	,	,	PUNCT
admet-1468	43	25	bangalore	bangalore	PROPN
admet-1468	43	26	.	.	PUNCT
admet-1468	44	1	the	the	DET
admet-1468	44	2	in	in	ADV
admet-1468	44	3	vitro	vitro	X
admet-1468	44	4	biological	biological	ADJ
admet-1468	44	5	activities	activity	NOUN
admet-1468	44	6	and	and	CCONJ
admet-1468	44	7	in	in	ADP
admet-1468	44	8	silico	silico	NOUN
admet-1468	44	9	predictions	prediction	NOUN
admet-1468	44	10	were	be	AUX
admet-1468	44	11	carried	carry	VERB
admet-1468	44	12	out	out	ADP
admet-1468	44	13	at	at	ADP
admet-1468	44	14	advanced	advanced	ADJ
admet-1468	44	15	scientific	scientific	ADJ
admet-1468	44	16	research	research	NOUN
admet-1468	44	17	laboratory	laboratory	NOUN
admet-1468	44	18	,	,	PUNCT
admet-1468	44	19	abeda	abeda	X
admet-1468	44	20	inamdar	inamdar	ADJ
admet-1468	44	21	senior	senior	ADJ
admet-1468	44	22	college	college	NOUN
admet-1468	44	23	,	,	PUNCT
admet-1468	44	24	pune	pune	NOUN
admet-1468	44	25	.	.	PUNCT
admet-1468	45	1	synthesis	synthesis	NOUN
admet-1468	45	2	of	of	ADP
admet-1468	45	3	coumarin	coumarin	NOUN
admet-1468	45	4	-	-	PUNCT
admet-1468	45	5	quinone	quinone	NOUN
admet-1468	45	6	hybrids	hybrid	NOUN
admet-1468	45	7	the	the	DET
admet-1468	45	8	procedure	procedure	NOUN
admet-1468	45	9	used	use	VERB
admet-1468	45	10	for	for	ADP
admet-1468	45	11	the	the	DET
admet-1468	45	12	synthesis	synthesis	NOUN
admet-1468	45	13	of	of	ADP
admet-1468	45	14	target	target	NOUN
admet-1468	45	15	coumarin	coumarin	NOUN
admet-1468	45	16	-	-	PUNCT
admet-1468	45	17	quinone	quinone	NOUN
admet-1468	45	18	hybrids	hybrid	NOUN
admet-1468	45	19	compounds	compound	NOUN
admet-1468	45	20	is	be	AUX
admet-1468	45	21	illustrated	illustrate	VERB
admet-1468	45	22	in	in	ADP
admet-1468	45	23	figure	figure	NOUN
admet-1468	45	24	1	1	NUM
admet-1468	45	25	.	.	X
admet-1468	46	1	2,6	2,6	NUM
admet-1468	46	2	-	-	ADJ
admet-1468	46	3	di	di	NOUN
admet-1468	46	4	-	-	PUNCT
admet-1468	46	5	tert	tert	NOUN
admet-1468	46	6	-	-	PUNCT
admet-1468	46	7	butyl-1,4	butyl-1,4	NOUN
admet-1468	46	8	-	-	PUNCT
admet-1468	46	9	benzoquinone	benzoquinone	NOUN
admet-1468	46	10	(	(	PUNCT
admet-1468	46	11	1	1	NUM
admet-1468	46	12	,	,	PUNCT
admet-1468	46	13	10	10	NUM
admet-1468	46	14	mmol	mmol	NOUN
admet-1468	46	15	)	)	PUNCT
admet-1468	46	16	and	and	CCONJ
admet-1468	46	17	ethyl	ethyl	PROPN
admet-1468	46	18	3	3	PROPN
admet-1468	46	19	-	-	PUNCT
admet-1468	46	20	hydrazinyl-3	hydrazinyl-3	NOUN
admet-1468	46	21	-	-	PUNCT
admet-1468	46	22	oxopropanoate	oxopropanoate	NOUN
admet-1468	46	23	(	(	PUNCT
admet-1468	46	24	2	2	NUM
admet-1468	46	25	,	,	PUNCT
admet-1468	46	26	10	10	NUM
admet-1468	46	27	mmol	mmol	NOUN
admet-1468	46	28	)	)	PUNCT
admet-1468	46	29	was	be	AUX
admet-1468	46	30	dissolved	dissolve	VERB
admet-1468	46	31	in	in	ADP
admet-1468	46	32	ethanol	ethanol	NOUN
admet-1468	46	33	.	.	PUNCT
admet-1468	47	1	after	after	ADP
admet-1468	47	2	complete	complete	ADJ
admet-1468	47	3	dissolution	dissolution	NOUN
admet-1468	47	4	,	,	PUNCT
admet-1468	47	5	a	a	DET
admet-1468	47	6	few	few	ADJ
admet-1468	47	7	drops	drop	NOUN
admet-1468	47	8	of	of	ADP
admet-1468	47	9	trifluoroacetic	trifluoroacetic	ADJ
admet-1468	47	10	acid	acid	NOUN
admet-1468	47	11	were	be	AUX
admet-1468	47	12	added	add	VERB
admet-1468	47	13	and	and	CCONJ
admet-1468	47	14	the	the	DET
admet-1468	47	15	mixture	mixture	NOUN
admet-1468	47	16	was	be	AUX
admet-1468	47	17	refluxed	refluxe	VERB
admet-1468	47	18	for	for	ADP
admet-1468	47	19	2	2	NUM
admet-1468	47	20	hours	hour	NOUN
admet-1468	47	21	.	.	PUNCT
admet-1468	48	1	the	the	DET
admet-1468	48	2	reaction	reaction	NOUN
admet-1468	48	3	mixture	mixture	NOUN
admet-1468	48	4	was	be	AUX
admet-1468	48	5	poured	pour	VERB
admet-1468	48	6	onto	onto	ADP
admet-1468	48	7	an	an	DET
admet-1468	48	8	ice	ice	NOUN
admet-1468	48	9	/	/	SYM
admet-1468	48	10	water	water	NOUN
admet-1468	48	11	mixture	mixture	NOUN
admet-1468	48	12	and	and	CCONJ
admet-1468	48	13	admet	admet	PROPN
admet-1468	48	14	&	&	CCONJ
admet-1468	48	15	dmpk	dmpk	PROPN
admet-1468	48	16	11(1	11(1	NUM
admet-1468	48	17	)	)	PUNCT
admet-1468	48	18	(	(	PUNCT
admet-1468	48	19	2023	2023	NUM
admet-1468	48	20	)	)	PUNCT
admet-1468	48	21	81	81	NUM
admet-1468	48	22	-	-	SYM
admet-1468	48	23	96	96	NUM
admet-1468	48	24	coumarin	coumarin	NOUN
admet-1468	48	25	-	-	PUNCT
admet-1468	48	26	quinone	quinone	NOUN
admet-1468	48	27	hybrids	hybrid	NOUN
admet-1468	48	28	doi	doi	NOUN
admet-1468	48	29	:	:	PUNCT
admet-1468	48	30	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	48	31	83	83	NUM
admet-1468	49	1	the	the	DET
admet-1468	49	2	separated	separated	ADJ
admet-1468	49	3	product	product	NOUN
admet-1468	49	4	was	be	AUX
admet-1468	49	5	collected	collect	VERB
admet-1468	49	6	,	,	PUNCT
admet-1468	49	7	washed	wash	VERB
admet-1468	49	8	with	with	ADP
admet-1468	49	9	cold	cold	ADJ
admet-1468	49	10	water	water	NOUN
admet-1468	49	11	several	several	ADJ
admet-1468	49	12	times	time	NOUN
admet-1468	49	13	,	,	PUNCT
admet-1468	49	14	and	and	CCONJ
admet-1468	49	15	recrystallized	recrystallize	VERB
admet-1468	49	16	from	from	ADP
admet-1468	49	17	ethanol	ethanol	NOUN
admet-1468	49	18	to	to	PART
admet-1468	49	19	obtain	obtain	VERB
admet-1468	49	20	2,6	2,6	NUM
admet-1468	49	21	-	-	ADJ
admet-1468	49	22	di	di	NOUN
admet-1468	49	23	-	-	PUNCT
admet-1468	49	24	tert	tert	NOUN
admet-1468	49	25	-	-	PUNCT
admet-1468	49	26	butyl-1,4	butyl-1,4	NOUN
admet-1468	49	27	-	-	PUNCT
admet-1468	49	28	benzoquinone	benzoquinone	NOUN
admet-1468	49	29	hydrazone	hydrazone	NOUN
admet-1468	49	30	(	(	PUNCT
admet-1468	49	31	3	3	NUM
admet-1468	49	32	)	)	PUNCT
admet-1468	49	33	.	.	PUNCT
admet-1468	50	1	a	a	DET
admet-1468	50	2	mixture	mixture	NOUN
admet-1468	50	3	of	of	ADP
admet-1468	50	4	(	(	PUNCT
admet-1468	50	5	3	3	NUM
admet-1468	50	6	)	)	PUNCT
admet-1468	50	7	and	and	CCONJ
admet-1468	50	8	substituted	substitute	VERB
admet-1468	50	9	salicylaldehyde	salicylaldehyde	NOUN
admet-1468	50	10	(	(	PUNCT
admet-1468	50	11	4	4	NUM
admet-1468	50	12	,	,	PUNCT
admet-1468	50	13	1eq	1eq	ADJ
admet-1468	50	14	)	)	PUNCT
admet-1468	50	15	was	be	AUX
admet-1468	50	16	dissolved	dissolve	VERB
admet-1468	50	17	in	in	ADP
admet-1468	50	18	ethanol	ethanol	NOUN
admet-1468	50	19	.	.	PUNCT
admet-1468	51	1	a	a	DET
admet-1468	51	2	few	few	ADJ
admet-1468	51	3	drops	drop	NOUN
admet-1468	51	4	of	of	ADP
admet-1468	51	5	piperidine	piperidine	NOUN
admet-1468	51	6	were	be	AUX
admet-1468	51	7	added	add	VERB
admet-1468	51	8	to	to	ADP
admet-1468	51	9	the	the	DET
admet-1468	51	10	mixture	mixture	NOUN
admet-1468	51	11	,	,	PUNCT
admet-1468	51	12	and	and	CCONJ
admet-1468	51	13	the	the	DET
admet-1468	51	14	reaction	reaction	NOUN
admet-1468	51	15	mixture	mixture	NOUN
admet-1468	51	16	was	be	AUX
admet-1468	51	17	stirred	stir	VERB
admet-1468	51	18	at	at	ADP
admet-1468	51	19	room	room	NOUN
admet-1468	51	20	temperature	temperature	NOUN
admet-1468	51	21	until	until	SCONJ
admet-1468	51	22	the	the	DET
admet-1468	51	23	reaction	reaction	NOUN
admet-1468	51	24	was	be	AUX
admet-1468	51	25	completed	complete	VERB
admet-1468	51	26	,	,	PUNCT
admet-1468	51	27	which	which	PRON
admet-1468	51	28	was	be	AUX
admet-1468	51	29	monitored	monitor	VERB
admet-1468	51	30	by	by	ADP
admet-1468	51	31	tlc	tlc	PROPN
admet-1468	51	32	.	.	PUNCT
admet-1468	52	1	after	after	ADP
admet-1468	52	2	completion	completion	NOUN
admet-1468	52	3	of	of	ADP
admet-1468	52	4	the	the	DET
admet-1468	52	5	reaction	reaction	NOUN
admet-1468	52	6	,	,	PUNCT
admet-1468	52	7	the	the	DET
admet-1468	52	8	reaction	reaction	NOUN
admet-1468	52	9	mixture	mixture	NOUN
admet-1468	52	10	was	be	AUX
admet-1468	52	11	neutralized	neutralize	VERB
admet-1468	52	12	with	with	ADP
admet-1468	52	13	dil	dil	PROPN
admet-1468	52	14	.	.	PUNCT
admet-1468	53	1	hcl	hcl	PROPN
admet-1468	53	2	and	and	CCONJ
admet-1468	53	3	formed	form	VERB
admet-1468	53	4	coumarin	coumarin	NOUN
admet-1468	53	5	-	-	PUNCT
admet-1468	53	6	quinone	quinone	NOUN
admet-1468	53	7	hybrids	hybrid	NOUN
admet-1468	53	8	(	(	PUNCT
admet-1468	53	9	5	5	NUM
admet-1468	53	10	)	)	PUNCT
admet-1468	53	11	were	be	AUX
admet-1468	53	12	isolated	isolate	VERB
admet-1468	53	13	by	by	ADP
admet-1468	53	14	filtration	filtration	NOUN
admet-1468	53	15	and	and	CCONJ
admet-1468	53	16	recrystallized	recrystallize	VERB
admet-1468	53	17	in	in	ADP
admet-1468	53	18	ethanol	ethanol	NOUN
admet-1468	53	19	.	.	PUNCT
admet-1468	54	1	the	the	DET
admet-1468	54	2	detailed	detailed	ADJ
admet-1468	54	3	physical	physical	ADJ
admet-1468	54	4	properties	property	NOUN
admet-1468	54	5	and	and	CCONJ
admet-1468	54	6	spectral	spectral	ADJ
admet-1468	54	7	characterization	characterization	NOUN
admet-1468	54	8	data	datum	NOUN
admet-1468	54	9	are	be	AUX
admet-1468	54	10	given	give	VERB
admet-1468	54	11	below	below	ADV
admet-1468	54	12	.	.	PUNCT
admet-1468	55	1	ethyl	ethyl	PROPN
admet-1468	55	2	2-(3,5	2-(3,5	PROPN
admet-1468	55	3	-	-	PUNCT
admet-1468	55	4	di	di	NOUN
admet-1468	55	5	-	-	PUNCT
admet-1468	55	6	tert	tert	NOUN
admet-1468	55	7	-	-	PUNCT
admet-1468	55	8	butyl-4	butyl-4	NOUN
admet-1468	55	9	-	-	PUNCT
admet-1468	55	10	oxocyclohexa-2,5	oxocyclohexa-2,5	NUM
admet-1468	55	11	-	-	PUNCT
admet-1468	55	12	dienylideneaminocarbamoyl)acetate	dienylideneaminocarbamoyl)acetate	NOUN
admet-1468	55	13	(	(	PUNCT
admet-1468	55	14	dtbh	dtbh	NOUN
admet-1468	55	15	):	):	PUNCT
admet-1468	55	16	yellow	yellow	ADJ
admet-1468	55	17	solid	solid	ADJ
admet-1468	55	18	(	(	PUNCT
admet-1468	55	19	95	95	NUM
admet-1468	55	20	%	%	NOUN
admet-1468	55	21	)	)	PUNCT
admet-1468	55	22	,	,	PUNCT
admet-1468	55	23	mp	mp	PROPN
admet-1468	55	24	164	164	NUM
admet-1468	55	25	-	-	SYM
admet-1468	55	26	166	166	NUM
admet-1468	55	27	°	°	NOUN
admet-1468	55	28	c	c	NOUN
admet-1468	55	29	,	,	PUNCT
admet-1468	55	30	hrms	hrm	NOUN
admet-1468	55	31	(	(	PUNCT
admet-1468	55	32	ei	ei	INTJ
admet-1468	55	33	):	):	PUNCT
admet-1468	55	34	c19h29n2o4	c19h29n2o4	PROPN
admet-1468	55	35	,	,	PUNCT
admet-1468	56	1	[	[	X
admet-1468	56	2	m+h	m+h	X
admet-1468	56	3	]	]	X
admet-1468	56	4	=	=	SYM
admet-1468	57	1	349.21	349.21	NUM
admet-1468	57	2	,	,	PUNCT
admet-1468	57	3	ftir(cm-1	ftir(cm-1	NUM
admet-1468	57	4	):	):	PUNCT
admet-1468	57	5	3739.30	3739.30	NUM
admet-1468	57	6	(	(	PUNCT
admet-1468	57	7	nh	nh	NOUN
admet-1468	57	8	)	)	PUNCT
admet-1468	57	9	,	,	PUNCT
admet-1468	57	10	1744.30	1744.30	NUM
admet-1468	57	11	(	(	PUNCT
admet-1468	57	12	lactone	lactone	PROPN
admet-1468	57	13	c	c	PROPN
admet-1468	57	14	=	=	NOUN
admet-1468	57	15	o	o	NOUN
admet-1468	57	16	)	)	PUNCT
admet-1468	57	17	,	,	PUNCT
admet-1468	57	18	1683.55	1683.55	NUM
admet-1468	57	19	(	(	PUNCT
admet-1468	57	20	c	c	NOUN
admet-1468	57	21	=	=	NOUN
admet-1468	57	22	o	o	NOUN
admet-1468	57	23	)	)	PUNCT
admet-1468	57	24	,	,	PUNCT
admet-1468	57	25	1624.73	1624.73	NUM
admet-1468	57	26	(	(	PUNCT
admet-1468	57	27	c	c	NOUN
admet-1468	57	28	=	=	NOUN
admet-1468	57	29	o	o	NOUN
admet-1468	57	30	)	)	PUNCT
admet-1468	57	31	,	,	PUNCT
admet-1468	57	32	1536.02	1536.02	NUM
admet-1468	57	33	(	(	PUNCT
admet-1468	57	34	c	c	NOUN
admet-1468	57	35	=	=	SYM
admet-1468	57	36	n	n	NUM
admet-1468	57	37	)	)	PUNCT
admet-1468	57	38	,	,	PUNCT
admet-1468	57	39	1315.21	1315.21	NUM
admet-1468	57	40	(	(	PUNCT
admet-1468	57	41	c	c	X
admet-1468	57	42	=	=	SYM
admet-1468	57	43	c	c	NOUN
admet-1468	57	44	)	)	PUNCT
admet-1468	57	45	,	,	PUNCT
admet-1468	57	46	1141.65	1141.65	NUM
admet-1468	57	47	1024.98	1024.98	NUM
admet-1468	57	48	(	(	PUNCT
admet-1468	57	49	c	c	NOUN
admet-1468	57	50	-	-	PUNCT
admet-1468	57	51	o	o	NOUN
admet-1468	57	52	)	)	PUNCT
admet-1468	57	53	,	,	PUNCT
admet-1468	57	54	,	,	PUNCT
admet-1468	57	55	1h	1h	NUM
admet-1468	57	56	-	-	PUNCT
admet-1468	57	57	nmr	nmr	NOUN
admet-1468	57	58	(	(	PUNCT
admet-1468	57	59	400mhz	400mhz	NUM
admet-1468	57	60	,	,	PUNCT
admet-1468	57	61	d	d	X
admet-1468	57	62	-	-	PUNCT
admet-1468	57	63	dmso	dmso	ADJ
admet-1468	57	64	,	,	PUNCT
admet-1468	57	65	(	(	PUNCT
admet-1468	57	66	δ	δ	PROPN
admet-1468	57	67	,	,	PUNCT
admet-1468	57	68	ppm	ppm	NOUN
admet-1468	57	69	):	):	PUNCT
admet-1468	57	70	1.23	1.23	NUM
admet-1468	57	71	(	(	PUNCT
admet-1468	57	72	s	s	PROPN
admet-1468	57	73	,	,	PUNCT
admet-1468	57	74	18h	18h	NOUN
admet-1468	57	75	)	)	PUNCT
admet-1468	57	76	,	,	PUNCT
admet-1468	57	77	4.10	4.10	NUM
admet-1468	57	78	(	(	PUNCT
admet-1468	57	79	q	q	NOUN
admet-1468	57	80	,	,	PUNCT
admet-1468	57	81	2h	2h	NUM
admet-1468	57	82	)	)	PUNCT
admet-1468	57	83	,	,	PUNCT
admet-1468	57	84	3.74	3.74	NUM
admet-1468	57	85	(	(	PUNCT
admet-1468	57	86	s	s	NOUN
admet-1468	57	87	,	,	PUNCT
admet-1468	57	88	2h	2h	NUM
admet-1468	57	89	)	)	PUNCT
admet-1468	57	90	,	,	PUNCT
admet-1468	57	91	1.21	1.21	NUM
admet-1468	57	92	(	(	PUNCT
admet-1468	57	93	t	t	PROPN
admet-1468	57	94	,	,	PUNCT
admet-1468	57	95	3h	3h	NUM
admet-1468	57	96	)	)	PUNCT
admet-1468	57	97	,	,	PUNCT
admet-1468	57	98	6.82	6.82	NUM
admet-1468	57	99	d	d	PROPN
admet-1468	57	100	,	,	PUNCT
admet-1468	57	101	1h	1h	NUM
admet-1468	57	102	)	)	PUNCT
admet-1468	57	103	,	,	PUNCT
admet-1468	57	104	7.74	7.74	NUM
admet-1468	57	105	(	(	PUNCT
admet-1468	57	106	d	d	PROPN
admet-1468	57	107	,	,	PUNCT
admet-1468	57	108	1h	1h	NUM
admet-1468	57	109	)	)	PUNCT
admet-1468	57	110	,	,	PUNCT
admet-1468	57	111	12.39	12.39	NUM
admet-1468	57	112	(	(	PUNCT
admet-1468	57	113	s	s	PROPN
admet-1468	57	114	,	,	PUNCT
admet-1468	57	115	1h	1h	NUM
admet-1468	57	116	,	,	PUNCT
admet-1468	57	117	–	–	PUNCT
admet-1468	57	118	nh	nh	NUM
admet-1468	57	119	)	)	PUNCT
admet-1468	57	120	,	,	PUNCT
admet-1468	57	121	13c	13c	NOUN
admet-1468	57	122	-	-	NOUN
admet-1468	57	123	nmr	nmr	NOUN
admet-1468	57	124	(	(	PUNCT
admet-1468	57	125	125mhz	125mhz	NUM
admet-1468	57	126	,	,	PUNCT
admet-1468	57	127	d	d	X
admet-1468	57	128	-	-	PUNCT
admet-1468	57	129	dmso	dmso	ADJ
admet-1468	57	130	):	):	PUNCT
admet-1468	57	131	186.77	186.77	NUM
admet-1468	57	132	,	,	PUNCT
admet-1468	57	133	166.03	166.03	NUM
admet-1468	57	134	,	,	PUNCT
admet-1468	57	135	158.42	158.42	NUM
admet-1468	57	136	,	,	PUNCT
admet-1468	57	137	154.57	154.57	NUM
admet-1468	57	138	,	,	PUNCT
admet-1468	57	139	151.10	151.10	NUM
admet-1468	57	140	,	,	PUNCT
admet-1468	57	141	150.61	150.61	NUM
admet-1468	57	142	,	,	PUNCT
admet-1468	57	143	146.68	146.68	NUM
admet-1468	57	144	,	,	PUNCT
admet-1468	57	145	135.22	135.22	NUM
admet-1468	57	146	,	,	PUNCT
admet-1468	57	147	133.21	133.21	NUM
admet-1468	57	148	,	,	PUNCT
admet-1468	57	149	130.26	130.26	NUM
admet-1468	57	150	,	,	PUNCT
admet-1468	57	151	125.94	125.94	NUM
admet-1468	57	152	,	,	PUNCT
admet-1468	57	153	118.52	118.52	NUM
admet-1468	57	154	,	,	PUNCT
admet-1468	57	155	117.20	117.20	NUM
admet-1468	57	156	,	,	PUNCT
admet-1468	57	157	116.13	116.13	NUM
admet-1468	57	158	,	,	PUNCT
admet-1468	57	159	35.55	35.55	NUM
admet-1468	57	160	,	,	PUNCT
admet-1468	57	161	29.46	29.46	NUM
admet-1468	57	162	n'-(3,5	n'-(3,5	NOUN
admet-1468	57	163	-	-	PUNCT
admet-1468	57	164	di	di	NOUN
admet-1468	57	165	-	-	PUNCT
admet-1468	57	166	tert	tert	NOUN
admet-1468	57	167	-	-	PUNCT
admet-1468	57	168	butyl-4	butyl-4	NOUN
admet-1468	57	169	-	-	PUNCT
admet-1468	57	170	oxocyclohexa-2,5	oxocyclohexa-2,5	NUM
admet-1468	57	171	-	-	PUNCT
admet-1468	57	172	dienylidene)-2	dienylidene)-2	NOUN
admet-1468	57	173	-	-	PUNCT
admet-1468	57	174	oxo-2h	oxo-2h	NOUN
admet-1468	57	175	-	-	PUNCT
admet-1468	57	176	chromene-3	chromene-3	NOUN
admet-1468	57	177	-	-	PUNCT
admet-1468	57	178	carbohydrazide	carbohydrazide	NOUN
admet-1468	57	179	(	(	PUNCT
admet-1468	57	180	dtbsa	dtbsa	NOUN
admet-1468	57	181	):	):	PUNCT
admet-1468	57	182	light	light	ADJ
admet-1468	57	183	orange	orange	PROPN
admet-1468	57	184	solid	solid	ADJ
admet-1468	57	185	(	(	PUNCT
admet-1468	57	186	85	85	NUM
admet-1468	57	187	%	%	NOUN
admet-1468	57	188	)	)	PUNCT
admet-1468	57	189	,	,	PUNCT
admet-1468	57	190	mp	mp	PROPN
admet-1468	57	191	134	134	NUM
admet-1468	57	192	-	-	SYM
admet-1468	57	193	136	136	NUM
admet-1468	57	194	°	°	NUM
admet-1468	57	195	c	c	NOUN
admet-1468	57	196	,	,	PUNCT
admet-1468	57	197	hrms	hrm	NOUN
admet-1468	57	198	(	(	PUNCT
admet-1468	57	199	ei	ei	NOUN
admet-1468	57	200	):	):	PUNCT
admet-1468	57	201	c24h27n2o4	c24h27n2o4	PROPN
admet-1468	57	202	,	,	PUNCT
admet-1468	58	1	[	[	X
admet-1468	58	2	m+h	m+h	X
admet-1468	58	3	]	]	X
admet-1468	58	4	=	=	X
admet-1468	59	1	407.20	407.20	NUM
admet-1468	59	2	,	,	PUNCT
admet-1468	59	3	ftir(cm1	ftir(cm1	NOUN
admet-1468	59	4	):	):	PUNCT
admet-1468	59	5	3739.30	3739.30	NUM
admet-1468	59	6	(	(	PUNCT
admet-1468	59	7	n	n	CCONJ
admet-1468	59	8	-	-	PUNCT
admet-1468	59	9	h	h	NOUN
admet-1468	59	10	)	)	PUNCT
admet-1468	59	11	,	,	PUNCT
admet-1468	59	12	1712.48	1712.48	NUM
admet-1468	59	13	(	(	PUNCT
admet-1468	59	14	lactone	lactone	NOUN
admet-1468	59	15	c	c	PROPN
admet-1468	59	16	=	=	NOUN
admet-1468	59	17	o	o	NOUN
admet-1468	59	18	)	)	PUNCT
admet-1468	59	19	,	,	PUNCT
admet-1468	59	20	1683.15	1683.15	NUM
admet-1468	59	21	(	(	PUNCT
admet-1468	59	22	c	c	NOUN
admet-1468	59	23	=	=	NOUN
admet-1468	59	24	o	o	NOUN
admet-1468	59	25	)	)	PUNCT
admet-1468	59	26	,	,	PUNCT
admet-1468	59	27	1624.22	1624.22	NUM
admet-1468	59	28	(	(	PUNCT
admet-1468	59	29	c	c	NOUN
admet-1468	59	30	=	=	NOUN
admet-1468	59	31	o	o	NOUN
admet-1468	59	32	)	)	PUNCT
admet-1468	59	33	,	,	PUNCT
admet-1468	59	34	1525.42	1525.42	NUM
admet-1468	59	35	(	(	PUNCT
admet-1468	59	36	c	c	NOUN
admet-1468	59	37	=	=	SYM
admet-1468	59	38	n	n	NUM
admet-1468	59	39	)	)	PUNCT
admet-1468	59	40	,	,	PUNCT
admet-1468	59	41	1301.72	1301.72	NUM
admet-1468	59	42	(	(	PUNCT
admet-1468	59	43	aromatic	aromatic	ADJ
admet-1468	59	44	c	c	NOUN
admet-1468	59	45	=	=	NOUN
admet-1468	59	46	c),1202.40	c),1202.40	PROPN
admet-1468	59	47	-	-	PUNCT
admet-1468	59	48	1024.98	1024.98	NUM
admet-1468	59	49	(	(	PUNCT
admet-1468	59	50	c	c	NOUN
admet-1468	59	51	-	-	PUNCT
admet-1468	59	52	o	o	NOUN
admet-1468	59	53	)	)	PUNCT
admet-1468	59	54	,	,	PUNCT
admet-1468	59	55	1h	1h	NUM
admet-1468	59	56	-	-	PUNCT
admet-1468	59	57	nmr	nmr	NOUN
admet-1468	59	58	(	(	PUNCT
admet-1468	59	59	400mhz	400mhz	NUM
admet-1468	59	60	,	,	PUNCT
admet-1468	59	61	cdcl3	cdcl3	PROPN
admet-1468	59	62	)	)	PUNCT
admet-1468	59	63	(	(	PUNCT
admet-1468	59	64	δ	δ	PROPN
admet-1468	59	65	,	,	PUNCT
admet-1468	59	66	ppm	ppm	ADJ
admet-1468	59	67	,	,	PUNCT
admet-1468	59	68	):	):	PUNCT
admet-1468	59	69	1.34	1.34	NUM
admet-1468	59	70	(	(	PUNCT
admet-1468	59	71	s	s	PROPN
admet-1468	59	72	,	,	PUNCT
admet-1468	59	73	18h	18h	NOUN
admet-1468	59	74	)	)	PUNCT
admet-1468	59	75	,	,	PUNCT
admet-1468	59	76	12.78	12.78	NUM
admet-1468	59	77	(	(	PUNCT
admet-1468	59	78	s	s	PROPN
admet-1468	59	79	,	,	PUNCT
admet-1468	59	80	1hnh	1hnh	NUM
admet-1468	59	81	)	)	PUNCT
admet-1468	59	82	,	,	PUNCT
admet-1468	59	83	9.15	9.15	NUM
admet-1468	59	84	(	(	PUNCT
admet-1468	59	85	s	s	PROPN
admet-1468	59	86	,	,	PUNCT
admet-1468	59	87	1h	1h	NUM
admet-1468	59	88	)	)	PUNCT
admet-1468	59	89	,	,	PUNCT
admet-1468	59	90	7.40	7.40	NUM
admet-1468	59	91	to	to	ADP
admet-1468	59	92	7.79	7.79	NUM
admet-1468	59	93	(	(	PUNCT
admet-1468	59	94	m	m	PROPN
admet-1468	59	95	,	,	PUNCT
admet-1468	59	96	4h	4h	NOUN
admet-1468	59	97	)	)	PUNCT
admet-1468	59	98	,	,	PUNCT
admet-1468	59	99	8.5	8.5	NUM
admet-1468	59	100	(	(	PUNCT
admet-1468	59	101	d	d	PROPN
admet-1468	59	102	,	,	PUNCT
admet-1468	59	103	1h	1h	NUM
admet-1468	59	104	)	)	PUNCT
admet-1468	59	105	,	,	PUNCT
admet-1468	59	106	7.04	7.04	NUM
admet-1468	59	107	(	(	PUNCT
admet-1468	59	108	s	s	PROPN
admet-1468	59	109	,	,	PUNCT
admet-1468	59	110	1h	1h	NUM
admet-1468	59	111	)	)	PUNCT
admet-1468	59	112	,	,	PUNCT
admet-1468	59	113	6.98	6.98	NUM
admet-1468	59	114	(	(	PUNCT
admet-1468	59	115	s	s	PROPN
admet-1468	59	116	,	,	PUNCT
admet-1468	59	117	1h	1h	NUM
admet-1468	59	118	)	)	PUNCT
admet-1468	59	119	,	,	PUNCT
admet-1468	59	120	13c	13c	NOUN
admet-1468	59	121	-	-	NOUN
admet-1468	59	122	nmr	nmr	NOUN
admet-1468	59	123	(	(	PUNCT
admet-1468	59	124	125mhz	125mhz	NUM
admet-1468	59	125	,	,	PUNCT
admet-1468	59	126	cdcl3	cdcl3	NOUN
admet-1468	59	127	):	):	PUNCT
admet-1468	59	128	186.77	186.77	NUM
admet-1468	59	129	,	,	PUNCT
admet-1468	59	130	166.03	166.03	NUM
admet-1468	59	131	,	,	PUNCT
admet-1468	59	132	158.42	158.42	NUM
admet-1468	59	133	,	,	PUNCT
admet-1468	59	134	154.57	154.57	NUM
admet-1468	59	135	,	,	PUNCT
admet-1468	59	136	151.10	151.10	NUM
admet-1468	59	137	,	,	PUNCT
admet-1468	59	138	150.61	150.61	NUM
admet-1468	59	139	,	,	PUNCT
admet-1468	59	140	146.68	146.68	NUM
admet-1468	59	141	,	,	PUNCT
admet-1468	59	142	135.22	135.22	NUM
admet-1468	59	143	,	,	PUNCT
admet-1468	59	144	133.21	133.21	NUM
admet-1468	59	145	,	,	PUNCT
admet-1468	59	146	130.26	130.26	NUM
admet-1468	59	147	,	,	PUNCT
admet-1468	59	148	125.94	125.94	NUM
admet-1468	59	149	,	,	PUNCT
admet-1468	59	150	118.52	118.52	NUM
admet-1468	59	151	,	,	PUNCT
admet-1468	59	152	117.20	117.20	NUM
admet-1468	59	153	,	,	PUNCT
admet-1468	59	154	116.13	116.13	NUM
admet-1468	59	155	,	,	PUNCT
admet-1468	59	156	35.55	35.55	NUM
admet-1468	59	157	,	,	PUNCT
admet-1468	59	158	29.46	29.46	NUM
admet-1468	59	159	.	.	PUNCT
admet-1468	60	1	n'-(3,5	n'-(3,5	NOUN
admet-1468	60	2	-	-	PUNCT
admet-1468	60	3	di	di	NOUN
admet-1468	60	4	-	-	PUNCT
admet-1468	60	5	tert	tert	NOUN
admet-1468	60	6	-	-	PUNCT
admet-1468	60	7	butyl-4	butyl-4	NOUN
admet-1468	60	8	-	-	PUNCT
admet-1468	60	9	oxocyclohexa-2,5	oxocyclohexa-2,5	NUM
admet-1468	60	10	-	-	PUNCT
admet-1468	60	11	dienylidene)-6	dienylidene)-6	VERB
admet-1468	60	12	-	-	PUNCT
admet-1468	60	13	chloro-2	chloro-2	VERB
admet-1468	60	14	-	-	PUNCT
admet-1468	60	15	oxo-2h	oxo-2h	ADJ
admet-1468	60	16	-	-	PUNCT
admet-1468	60	17	chromene-3carbohydrazide	chromene-3carbohydrazide	NOUN
admet-1468	60	18	(	(	PUNCT
admet-1468	60	19	dtbsc	dtbsc	PROPN
admet-1468	60	20	):	):	PUNCT
admet-1468	60	21	orange	orange	PROPN
admet-1468	60	22	solid	solid	ADJ
admet-1468	60	23	(	(	PUNCT
admet-1468	60	24	90	90	NUM
admet-1468	60	25	%	%	NOUN
admet-1468	60	26	)	)	PUNCT
admet-1468	60	27	,	,	PUNCT
admet-1468	60	28	mp	mp	PROPN
admet-1468	60	29	186	186	NUM
admet-1468	60	30	-	-	SYM
admet-1468	60	31	188	188	NUM
admet-1468	60	32	°	°	NOUN
admet-1468	60	33	c	c	NOUN
admet-1468	60	34	,	,	PUNCT
admet-1468	60	35	hrms(ei	hrms(ei	NOUN
admet-1468	60	36	):	):	PUNCT
admet-1468	60	37	c24h26cln2o4	c24h26cln2o4	NOUN
admet-1468	60	38	,	,	PUNCT
admet-1468	60	39	[	[	X
admet-1468	60	40	m+h	m+h	X
admet-1468	60	41	]	]	X
admet-1468	60	42	=	=	SYM
admet-1468	61	1	441.16	441.16	NUM
admet-1468	61	2	,	,	PUNCT
admet-1468	61	3	ftir	ftir	X
admet-1468	61	4	(	(	PUNCT
admet-1468	61	5	cm-1	cm-1	PROPN
admet-1468	61	6	):	):	PUNCT
admet-1468	61	7	3739.30	3739.30	NUM
admet-1468	61	8	(	(	PUNCT
admet-1468	61	9	n	n	CCONJ
admet-1468	61	10	-	-	PUNCT
admet-1468	61	11	h	h	NOUN
admet-1468	61	12	)	)	PUNCT
admet-1468	61	13	,	,	PUNCT
admet-1468	61	14	1712.48	1712.48	NUM
admet-1468	61	15	(	(	PUNCT
admet-1468	61	16	lactone	lactone	NOUN
admet-1468	61	17	c	c	PROPN
admet-1468	61	18	=	=	NOUN
admet-1468	61	19	o	o	NOUN
admet-1468	61	20	)	)	PUNCT
admet-1468	61	21	,	,	PUNCT
admet-1468	61	22	1525.42	1525.42	NUM
admet-1468	61	23	(	(	PUNCT
admet-1468	61	24	c	c	NOUN
admet-1468	61	25	=	=	SYM
admet-1468	61	26	n	n	NUM
admet-1468	61	27	)	)	PUNCT
admet-1468	61	28	,	,	PUNCT
admet-1468	61	29	1301.72	1301.72	NUM
admet-1468	61	30	(	(	PUNCT
admet-1468	61	31	aromatic	aromatic	ADJ
admet-1468	61	32	c	c	NOUN
admet-1468	61	33	=	=	SYM
admet-1468	61	34	c	c	NOUN
admet-1468	61	35	)	)	PUNCT
admet-1468	61	36	,	,	PUNCT
admet-1468	61	37	1202.401024.98	1202.401024.98	NUM
admet-1468	61	38	(	(	PUNCT
admet-1468	61	39	c	c	NOUN
admet-1468	61	40	-	-	PUNCT
admet-1468	61	41	o	o	NOUN
admet-1468	61	42	)	)	PUNCT
admet-1468	61	43	,	,	PUNCT
admet-1468	61	44	1h	1h	NUM
admet-1468	61	45	-	-	PUNCT
admet-1468	61	46	nmr	nmr	NOUN
admet-1468	61	47	(	(	PUNCT
admet-1468	61	48	400mhz	400mhz	NUM
admet-1468	61	49	,	,	PUNCT
admet-1468	61	50	cdcl3	cdcl3	PROPN
admet-1468	61	51	)	)	PUNCT
admet-1468	61	52	(	(	PUNCT
admet-1468	61	53	δ	δ	PROPN
admet-1468	61	54	,	,	PUNCT
admet-1468	61	55	ppm	ppm	ADJ
admet-1468	61	56	,	,	PUNCT
admet-1468	61	57	):	):	PUNCT
admet-1468	61	58	1.30	1.30	NUM
admet-1468	61	59	(	(	PUNCT
admet-1468	61	60	s	s	PROPN
admet-1468	61	61	,	,	PUNCT
admet-1468	61	62	18h	18h	NOUN
admet-1468	61	63	)	)	PUNCT
admet-1468	61	64	,	,	PUNCT
admet-1468	61	65	12.67	12.67	NUM
admet-1468	61	66	(	(	PUNCT
admet-1468	61	67	s	s	PROPN
admet-1468	61	68	,	,	PUNCT
admet-1468	61	69	1h	1h	NUM
admet-1468	61	70	,	,	PUNCT
admet-1468	61	71	-nh	-nh	ADJ
admet-1468	61	72	)	)	PUNCT
admet-1468	61	73	,	,	PUNCT
admet-1468	61	74	9.07	9.07	NUM
admet-1468	61	75	(	(	PUNCT
admet-1468	61	76	s	s	PROPN
admet-1468	61	77	,	,	PUNCT
admet-1468	61	78	1h	1h	NUM
admet-1468	61	79	)	)	PUNCT
admet-1468	61	80	,	,	PUNCT
admet-1468	61	81	7.75	7.75	NUM
admet-1468	61	82	(	(	PUNCT
admet-1468	61	83	d	d	NOUN
admet-1468	61	84	,	,	PUNCT
admet-1468	61	85	j=7.69hz	j=7.69hz	PROPN
admet-1468	61	86	,	,	PUNCT
admet-1468	61	87	1h	1h	NUM
admet-1468	61	88	)	)	PUNCT
admet-1468	61	89	,	,	PUNCT
admet-1468	61	90	7.69	7.69	NUM
admet-1468	61	91	(	(	PUNCT
admet-1468	61	92	dd	dd	PROPN
admet-1468	61	93	,	,	PUNCT
admet-1468	61	94	j=7.69	j=7.69	NOUN
admet-1468	61	95	and	and	CCONJ
admet-1468	61	96	8.8	8.8	NUM
admet-1468	61	97	hz	hz	NOUN
admet-1468	61	98	,	,	PUNCT
admet-1468	61	99	1h	1h	NUM
admet-1468	61	100	)	)	PUNCT
admet-1468	61	101	,	,	PUNCT
admet-1468	61	102	7.42	7.42	NUM
admet-1468	61	103	(	(	PUNCT
admet-1468	61	104	d	d	NOUN
admet-1468	61	105	,	,	PUNCT
admet-1468	61	106	j=8.8hz	j=8.8hz	NOUN
admet-1468	61	107	,	,	PUNCT
admet-1468	61	108	1h	1h	NUM
admet-1468	61	109	)	)	PUNCT
admet-1468	61	110	,	,	PUNCT
admet-1468	61	111	7.02	7.02	NUM
admet-1468	61	112	(	(	PUNCT
admet-1468	61	113	s	s	PROPN
admet-1468	61	114	,	,	PUNCT
admet-1468	61	115	1h	1h	NUM
admet-1468	61	116	)	)	PUNCT
admet-1468	61	117	,	,	PUNCT
admet-1468	61	118	6.96	6.96	NUM
admet-1468	61	119	(	(	PUNCT
admet-1468	61	120	s	s	PROPN
admet-1468	61	121	,	,	PUNCT
admet-1468	61	122	1h	1h	NUM
admet-1468	61	123	)	)	PUNCT
admet-1468	61	124	,	,	PUNCT
admet-1468	61	125	13c	13c	NOUN
admet-1468	61	126	-	-	NOUN
admet-1468	61	127	nmr	nmr	NOUN
admet-1468	61	128	(	(	PUNCT
admet-1468	61	129	125mhz	125mhz	NUM
admet-1468	61	130	,	,	PUNCT
admet-1468	61	131	cdcl3	cdcl3	NOUN
admet-1468	61	132	):	):	PUNCT
admet-1468	61	133	186.68	186.68	NUM
admet-1468	61	134	,	,	PUNCT
admet-1468	61	135	167.08	167.08	NUM
admet-1468	61	136	,	,	PUNCT
admet-1468	61	137	157.93	157.93	NUM
admet-1468	61	138	,	,	PUNCT
admet-1468	61	139	154.41	154.41	NUM
admet-1468	61	140	,	,	PUNCT
admet-1468	61	141	153.91	153.91	NUM
admet-1468	61	142	,	,	PUNCT
admet-1468	61	143	150.52	150.52	NUM
admet-1468	61	144	,	,	PUNCT
admet-1468	61	145	149.29	149.29	NUM
admet-1468	61	146	,	,	PUNCT
admet-1468	61	147	146.97	146.97	NUM
admet-1468	61	148	,	,	PUNCT
admet-1468	61	149	135.07	135.07	NUM
admet-1468	61	150	,	,	PUNCT
admet-1468	61	151	133.29	133.29	NUM
admet-1468	61	152	,	,	PUNCT
admet-1468	61	153	129.12	129.12	NUM
admet-1468	61	154	,	,	PUNCT
admet-1468	61	155	118.37	118.37	NUM
admet-1468	61	156	,	,	PUNCT
admet-1468	61	157	116.09	116.09	NUM
admet-1468	61	158	,	,	PUNCT
admet-1468	61	159	115.62	115.62	NUM
admet-1468	61	160	,	,	PUNCT
admet-1468	61	161	35.47	35.47	NUM
admet-1468	61	162	,	,	PUNCT
admet-1468	61	163	29.44	29.44	NUM
admet-1468	61	164	.	.	PUNCT
admet-1468	62	1	n'-(3,5	n'-(3,5	NOUN
admet-1468	62	2	-	-	PUNCT
admet-1468	62	3	di	di	NOUN
admet-1468	62	4	-	-	PUNCT
admet-1468	62	5	tert	tert	NOUN
admet-1468	62	6	-	-	PUNCT
admet-1468	62	7	butyl-4	butyl-4	NOUN
admet-1468	62	8	-	-	PUNCT
admet-1468	62	9	oxocyclohexa-2,5	oxocyclohexa-2,5	NUM
admet-1468	62	10	-	-	PUNCT
admet-1468	62	11	dienylidene)-6	dienylidene)-6	VERB
admet-1468	62	12	-	-	PUNCT
admet-1468	62	13	bromo-2	bromo-2	VERB
admet-1468	62	14	-	-	PUNCT
admet-1468	62	15	oxo-2h	oxo-2h	ADJ
admet-1468	62	16	-	-	PUNCT
admet-1468	62	17	chromene-3carbohydrazide	chromene-3carbohydrazide	NOUN
admet-1468	62	18	(	(	PUNCT
admet-1468	62	19	dtbsb	dtbsb	ADJ
admet-1468	62	20	):	):	PUNCT
admet-1468	62	21	brown	brown	ADJ
admet-1468	62	22	solid	solid	ADJ
admet-1468	62	23	(	(	PUNCT
admet-1468	62	24	92	92	NUM
admet-1468	62	25	%	%	NOUN
admet-1468	62	26	)	)	PUNCT
admet-1468	62	27	,	,	PUNCT
admet-1468	62	28	mp	mp	PROPN
admet-1468	62	29	152	152	NUM
admet-1468	62	30	-	-	SYM
admet-1468	62	31	156	156	NUM
admet-1468	62	32	°	°	NOUN
admet-1468	62	33	c	c	NOUN
admet-1468	62	34	,	,	PUNCT
admet-1468	62	35	hrms(ei	hrms(ei	NOUN
admet-1468	62	36	):	):	PUNCT
admet-1468	62	37	c24h26brn2o4	c24h26brn2o4	NOUN
admet-1468	62	38	,	,	PUNCT
admet-1468	63	1	[	[	X
admet-1468	63	2	m+h	m+h	X
admet-1468	63	3	]	]	X
admet-1468	63	4	=	=	SYM
admet-1468	64	1	485.11	485.11	NUM
admet-1468	64	2	,	,	PUNCT
admet-1468	64	3	ftir	ftir	X
admet-1468	64	4	(	(	PUNCT
admet-1468	64	5	cm-1):3745.08(n	cm-1):3745.08(n	NOUN
admet-1468	64	6	-	-	PUNCT
admet-1468	64	7	h	h	NOUN
admet-1468	64	8	)	)	PUNCT
admet-1468	64	9	,	,	PUNCT
admet-1468	64	10	1712.48	1712.48	NUM
admet-1468	64	11	(	(	PUNCT
admet-1468	64	12	c	c	NOUN
admet-1468	64	13	=	=	NOUN
admet-1468	64	14	o	o	NOUN
admet-1468	64	15	)	)	PUNCT
admet-1468	64	16	,	,	PUNCT
admet-1468	64	17	1640.16	1640.16	NUM
admet-1468	64	18	(	(	PUNCT
admet-1468	64	19	c	c	NOUN
admet-1468	64	20	=	=	NOUN
admet-1468	64	21	o	o	NOUN
admet-1468	64	22	)	)	PUNCT
admet-1468	64	23	,	,	PUNCT
admet-1468	64	24	1525.10	1525.10	NUM
admet-1468	64	25	(	(	PUNCT
admet-1468	64	26	c	c	NOUN
admet-1468	64	27	=	=	SYM
admet-1468	64	28	n	n	CCONJ
admet-1468	64	29	)	)	PUNCT
admet-1468	64	30	1363.43	1363.43	NUM
admet-1468	64	31	(	(	PUNCT
admet-1468	64	32	c	c	NOUN
admet-1468	64	33	=	=	SYM
admet-1468	64	34	c	c	NOUN
admet-1468	64	35	)	)	PUNCT
admet-1468	64	36	,	,	PUNCT
admet-1468	64	37	1197.58	1197.58	NUM
admet-1468	64	38	1014.37	1014.37	NUM
admet-1468	64	39	(	(	PUNCT
admet-1468	64	40	c	c	NOUN
admet-1468	64	41	-	-	PUNCT
admet-1468	64	42	o	o	NOUN
admet-1468	64	43	)	)	PUNCT
admet-1468	64	44	,	,	PUNCT
admet-1468	64	45	1h	1h	NUM
admet-1468	64	46	-	-	PUNCT
admet-1468	64	47	nmr	nmr	NOUN
admet-1468	64	48	(	(	PUNCT
admet-1468	64	49	400mhz	400mhz	NUM
admet-1468	64	50	,	,	PUNCT
admet-1468	64	51	cdcl3	cdcl3	PROPN
admet-1468	64	52	)	)	PUNCT
admet-1468	64	53	(	(	PUNCT
admet-1468	64	54	δ	δ	PROPN
admet-1468	64	55	,	,	PUNCT
admet-1468	64	56	ppm	ppm	ADJ
admet-1468	64	57	,	,	PUNCT
admet-1468	64	58	):	):	PUNCT
admet-1468	64	59	1.34	1.34	NUM
admet-1468	64	60	(	(	PUNCT
admet-1468	64	61	s	s	PROPN
admet-1468	64	62	,	,	PUNCT
admet-1468	64	63	18h	18h	NOUN
admet-1468	64	64	)	)	PUNCT
admet-1468	64	65	,	,	PUNCT
admet-1468	64	66	12.67	12.67	NUM
admet-1468	64	67	(	(	PUNCT
admet-1468	64	68	s	s	PROPN
admet-1468	64	69	,	,	PUNCT
admet-1468	64	70	1h	1h	NUM
admet-1468	64	71	,	,	PUNCT
admet-1468	64	72	-nh	-nh	ADJ
admet-1468	64	73	)	)	PUNCT
admet-1468	64	74	,	,	PUNCT
admet-1468	64	75	9.061	9.061	NUM
admet-1468	64	76	(	(	PUNCT
admet-1468	64	77	s	s	PROPN
admet-1468	64	78	,	,	PUNCT
admet-1468	64	79	1h	1h	NUM
admet-1468	64	80	)	)	PUNCT
admet-1468	64	81	,	,	PUNCT
admet-1468	64	82	7.91	7.91	NUM
admet-1468	64	83	(	(	PUNCT
admet-1468	64	84	s	s	PROPN
admet-1468	64	85	,	,	PUNCT
admet-1468	64	86	1h	1h	NUM
admet-1468	64	87	)	)	PUNCT
admet-1468	64	88	,	,	PUNCT
admet-1468	64	89	7.83	7.83	NUM
admet-1468	64	90	(	(	PUNCT
admet-1468	64	91	d	d	NOUN
admet-1468	64	92	,	,	PUNCT
admet-1468	64	93	j=8.8	j=8.8	PROPN
admet-1468	64	94	hz	hz	PROPN
admet-1468	64	95	,	,	PUNCT
admet-1468	64	96	1h	1h	NUM
admet-1468	64	97	)	)	PUNCT
admet-1468	64	98	,	,	PUNCT
admet-1468	64	99	7.36	7.36	NUM
admet-1468	64	100	(	(	PUNCT
admet-1468	64	101	d	d	NOUN
admet-1468	64	102	,	,	PUNCT
admet-1468	64	103	j=8.8	j=8.8	PROPN
admet-1468	64	104	hz	hz	PROPN
admet-1468	64	105	,	,	PUNCT
admet-1468	64	106	1h	1h	NUM
admet-1468	64	107	)	)	PUNCT
admet-1468	64	108	,	,	PUNCT
admet-1468	64	109	7.17	7.17	NUM
admet-1468	64	110	(	(	PUNCT
admet-1468	64	111	s	s	PROPN
admet-1468	64	112	,	,	PUNCT
admet-1468	64	113	1h	1h	NUM
admet-1468	64	114	)	)	PUNCT
admet-1468	64	115	,	,	PUNCT
admet-1468	64	116	6.86	6.86	NUM
admet-1468	64	117	(	(	PUNCT
admet-1468	64	118	s	s	PROPN
admet-1468	64	119	,	,	PUNCT
admet-1468	64	120	1h	1h	NUM
admet-1468	64	121	)	)	PUNCT
admet-1468	64	122	,	,	PUNCT
admet-1468	64	123	13c	13c	NOUN
admet-1468	64	124	-	-	NOUN
admet-1468	64	125	nmr	nmr	NOUN
admet-1468	64	126	(	(	PUNCT
admet-1468	64	127	125mhz	125mhz	NUM
admet-1468	64	128	,	,	PUNCT
admet-1468	64	129	cdcl3	cdcl3	NOUN
admet-1468	64	130	):	):	PUNCT
admet-1468	64	131	186.71	186.71	NUM
admet-1468	64	132	,	,	PUNCT
admet-1468	64	133	167.08	167.08	NUM
admet-1468	64	134	,	,	PUNCT
admet-1468	64	135	161.55	161.55	NUM
admet-1468	64	136	,	,	PUNCT
admet-1468	64	137	157.91	157.91	NUM
admet-1468	64	138	,	,	PUNCT
admet-1468	64	139	154.41	154.41	NUM
admet-1468	64	140	,	,	PUNCT
admet-1468	64	141	150.50	150.50	NUM
admet-1468	64	142	,	,	PUNCT
admet-1468	64	143	149.18	149.18	NUM
admet-1468	64	144	,	,	PUNCT
admet-1468	64	145	146.96	146.96	NUM
admet-1468	64	146	,	,	PUNCT
admet-1468	64	147	137.85	137.85	NUM
admet-1468	64	148	,	,	PUNCT
admet-1468	64	149	133.09	133.09	NUM
admet-1468	64	150	,	,	PUNCT
admet-1468	64	151	132.76	132.76	NUM
admet-1468	64	152	,	,	PUNCT
admet-1468	64	153	118.65	118.65	NUM
admet-1468	64	154	,	,	PUNCT
admet-1468	64	155	116.36	116.36	NUM
admet-1468	64	156	,	,	PUNCT
admet-1468	64	157	115.64	115.64	NUM
admet-1468	64	158	,	,	PUNCT
admet-1468	64	159	36.38	36.38	NUM
admet-1468	64	160	,	,	PUNCT
admet-1468	64	161	29.45	29.45	NUM
admet-1468	64	162	.	.	PUNCT
admet-1468	65	1	n'-(3,5	n'-(3,5	NOUN
admet-1468	65	2	-	-	PUNCT
admet-1468	65	3	di	di	NOUN
admet-1468	65	4	-	-	PUNCT
admet-1468	65	5	tert	tert	NOUN
admet-1468	65	6	-	-	PUNCT
admet-1468	65	7	butyl-4	butyl-4	NOUN
admet-1468	65	8	-	-	PUNCT
admet-1468	65	9	oxocyclohexa-2,5	oxocyclohexa-2,5	NUM
admet-1468	65	10	-	-	PUNCT
admet-1468	65	11	dienylidene)-6	dienylidene)-6	VERB
admet-1468	65	12	-	-	PUNCT
admet-1468	65	13	nitro-2	nitro-2	NUM
admet-1468	65	14	-	-	PUNCT
admet-1468	65	15	oxo-2h	oxo-2h	ADJ
admet-1468	65	16	-	-	PUNCT
admet-1468	65	17	chromene-3carbohydrazide	chromene-3carbohydrazide	NOUN
admet-1468	65	18	(	(	PUNCT
admet-1468	65	19	dtbsn	dtbsn	NOUN
admet-1468	65	20	):	):	PUNCT
admet-1468	65	21	dark	dark	ADJ
admet-1468	65	22	brown	brown	ADJ
admet-1468	65	23	solid	solid	ADJ
admet-1468	65	24	(	(	PUNCT
admet-1468	65	25	92	92	NUM
admet-1468	65	26	%	%	NOUN
admet-1468	65	27	)	)	PUNCT
admet-1468	65	28	,	,	PUNCT
admet-1468	65	29	mp	mp	PROPN
admet-1468	65	30	118	118	NUM
admet-1468	65	31	-	-	SYM
admet-1468	65	32	120	120	NUM
admet-1468	65	33	°	°	NOUN
admet-1468	65	34	c	c	NOUN
admet-1468	65	35	,	,	PUNCT
admet-1468	65	36	hrms(ei	hrms(ei	NOUN
admet-1468	65	37	):	):	PUNCT
admet-1468	65	38	c24h26n3o6	c24h26n3o6	PROPN
admet-1468	65	39	,	,	PUNCT
admet-1468	65	40	[	[	X
admet-1468	65	41	m+h	m+h	X
admet-1468	65	42	]	]	X
admet-1468	65	43	=	=	SYM
admet-1468	65	44	452.18	452.18	NUM
admet-1468	65	45	,	,	PUNCT
admet-1468	65	46	ftir	ftir	X
admet-1468	65	47	(	(	PUNCT
admet-1468	65	48	cm-1):3739.30(n	cm-1):3739.30(n	PROPN
admet-1468	65	49	-	-	NOUN
admet-1468	65	50	h	h	NOUN
admet-1468	65	51	)	)	PUNCT
admet-1468	65	52	,	,	PUNCT
admet-1468	65	53	1681.62	1681.62	NUM
admet-1468	65	54	(	(	PUNCT
admet-1468	65	55	c	c	NOUN
admet-1468	65	56	=	=	NOUN
admet-1468	65	57	o	o	NOUN
admet-1468	65	58	)	)	PUNCT
admet-1468	65	59	,	,	PUNCT
admet-1468	65	60	1337.39	1337.39	NUM
admet-1468	65	61	to	to	ADP
admet-1468	65	62	1509.99	1509.99	NUM
admet-1468	65	63	(	(	PUNCT
admet-1468	65	64	aromatic	aromatic	ADJ
admet-1468	65	65	,	,	PUNCT
admet-1468	65	66	-no2	-no2	PROPN
admet-1468	65	67	)	)	PUNCT
admet-1468	65	68	,	,	PUNCT
admet-1468	65	69	1293.04	1293.04	NUM
admet-1468	65	70	1020.16(c	1020.16(c	NUM
admet-1468	65	71	-	-	PUNCT
admet-1468	65	72	o	o	NOUN
admet-1468	65	73	)	)	PUNCT
admet-1468	65	74	,	,	PUNCT
admet-1468	65	75	1h	1h	NUM
admet-1468	65	76	-	-	PUNCT
admet-1468	65	77	nmr	nmr	NOUN
admet-1468	65	78	(	(	PUNCT
admet-1468	65	79	400mhz	400mhz	NUM
admet-1468	65	80	,	,	PUNCT
admet-1468	65	81	cdcl3	cdcl3	PROPN
admet-1468	65	82	)	)	PUNCT
admet-1468	65	83	(	(	PUNCT
admet-1468	65	84	δ	δ	PROPN
admet-1468	65	85	,	,	PUNCT
admet-1468	65	86	ppm	ppm	ADJ
admet-1468	65	87	,	,	PUNCT
admet-1468	65	88	):	):	PUNCT
admet-1468	65	89	1.28	1.28	NUM
admet-1468	65	90	(	(	PUNCT
admet-1468	65	91	s	s	PROPN
admet-1468	65	92	,	,	PUNCT
admet-1468	65	93	18h	18h	NOUN
admet-1468	65	94	)	)	PUNCT
admet-1468	65	95	,	,	PUNCT
admet-1468	65	96	10.00	10.00	NUM
admet-1468	65	97	(	(	PUNCT
admet-1468	65	98	s	s	PROPN
admet-1468	65	99	,	,	PUNCT
admet-1468	65	100	1h	1h	NUM
admet-1468	65	101	,	,	PUNCT
admet-1468	65	102	-nh	-nh	ADJ
admet-1468	65	103	)	)	PUNCT
admet-1468	65	104	,	,	PUNCT
admet-1468	65	105	9.21	9.21	NUM
admet-1468	65	106	(	(	PUNCT
admet-1468	65	107	s	s	PROPN
admet-1468	65	108	,	,	PUNCT
admet-1468	65	109	1h	1h	NUM
admet-1468	65	110	)	)	PUNCT
admet-1468	65	111	,	,	PUNCT
admet-1468	65	112	8.70	8.70	NUM
admet-1468	65	113	(	(	PUNCT
admet-1468	65	114	d	d	NOUN
admet-1468	65	115	,	,	PUNCT
admet-1468	65	116	j=2.4hz	j=2.4hz	PROPN
admet-1468	65	117	,	,	PUNCT
admet-1468	65	118	1h	1h	NUM
admet-1468	65	119	)	)	PUNCT
admet-1468	65	120	,	,	PUNCT
admet-1468	65	121	8.07	8.07	NUM
admet-1468	65	122	(	(	PUNCT
admet-1468	65	123	dd	dd	NOUN
admet-1468	65	124	,	,	PUNCT
admet-1468	65	125	j=2.4	j=2.4	NOUN
admet-1468	65	126	and	and	CCONJ
admet-1468	65	127	2.8	2.8	NUM
admet-1468	65	128	hz	hz	NOUN
admet-1468	65	129	,	,	PUNCT
admet-1468	65	130	1h	1h	NUM
admet-1468	65	131	)	)	PUNCT
admet-1468	65	132	,	,	PUNCT
admet-1468	65	133	7.91	7.91	NUM
admet-1468	65	134	(	(	PUNCT
admet-1468	65	135	d	d	PROPN
admet-1468	65	136	,	,	PUNCT
admet-1468	65	137	j=2.8	j=2.8	PROPN
admet-1468	65	138	hz	hz	NOUN
admet-1468	65	139	,	,	PUNCT
admet-1468	65	140	1h	1h	NUM
admet-1468	65	141	)	)	PUNCT
admet-1468	65	142	,	,	PUNCT
admet-1468	65	143	7.26	7.26	NUM
admet-1468	65	144	(	(	PUNCT
admet-1468	65	145	s	s	PROPN
admet-1468	65	146	,	,	PUNCT
admet-1468	65	147	1h	1h	NUM
admet-1468	65	148	)	)	PUNCT
admet-1468	65	149	,	,	PUNCT
admet-1468	65	150	6.84	6.84	NUM
admet-1468	65	151	(	(	PUNCT
admet-1468	65	152	s	s	PROPN
admet-1468	65	153	,	,	PUNCT
admet-1468	65	154	1h	1h	NUM
admet-1468	65	155	)	)	PUNCT
admet-1468	65	156	,	,	PUNCT
admet-1468	65	157	13cnmr	13cnmr	NUM
admet-1468	65	158	(	(	PUNCT
admet-1468	65	159	125mhz	125mhz	NUM
admet-1468	65	160	,	,	PUNCT
admet-1468	65	161	cdcl3	cdcl3	NOUN
admet-1468	65	162	):	):	PUNCT
admet-1468	65	163	186.74	186.74	NUM
admet-1468	65	164	,	,	PUNCT
admet-1468	65	165	165.42	165.42	NUM
admet-1468	65	166	,	,	PUNCT
admet-1468	65	167	159.32	159.32	NUM
admet-1468	65	168	,	,	PUNCT
admet-1468	65	169	153.62	153.62	NUM
admet-1468	65	170	,	,	PUNCT
admet-1468	65	171	151.61	151.61	NUM
admet-1468	65	172	,	,	PUNCT
admet-1468	65	173	149.17	149.17	NUM
admet-1468	65	174	,	,	PUNCT
admet-1468	65	175	144.96	144.96	NUM
admet-1468	65	176	,	,	PUNCT
admet-1468	65	177	138.61	138.61	NUM
admet-1468	65	178	,	,	PUNCT
admet-1468	65	179	136.54	136.54	NUM
admet-1468	65	180	,	,	PUNCT
admet-1468	65	181	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	65	182	a.	a.	NOUN
admet-1468	65	183	pangal	pangal	PROPN
admet-1468	65	184	and	and	CCONJ
admet-1468	65	185	k.	k.	PROPN
admet-1468	65	186	ahmed	ahmed	PROPN
admet-1468	65	187	admet	admet	PROPN
admet-1468	65	188	&	&	CCONJ
admet-1468	65	189	dmpk	dmpk	PROPN
admet-1468	65	190	11(1	11(1	NUM
admet-1468	65	191	)	)	PUNCT
admet-1468	65	192	(	(	PUNCT
admet-1468	65	193	2023	2023	NUM
admet-1468	65	194	)	)	PUNCT
admet-1468	65	195	81	81	NUM
admet-1468	65	196	-	-	SYM
admet-1468	65	197	96	96	NUM
admet-1468	65	198	84	84	NUM
admet-1468	65	199	132.96	132.96	NUM
admet-1468	65	200	,	,	PUNCT
admet-1468	65	201	128.04	128.04	NUM
admet-1468	65	202	,	,	PUNCT
admet-1468	65	203	118.31	118.31	NUM
admet-1468	65	204	,	,	PUNCT
admet-1468	65	205	116.85	116.85	NUM
admet-1468	65	206	,	,	PUNCT
admet-1468	65	207	115.80	115.80	NUM
admet-1468	65	208	,	,	PUNCT
admet-1468	65	209	34.38	34.38	NUM
admet-1468	65	210	,	,	PUNCT
admet-1468	65	211	29.51	29.51	NUM
admet-1468	65	212	.	.	PUNCT
admet-1468	66	1	antimicrobial	antimicrobial	ADJ
admet-1468	66	2	activity	activity	NOUN
admet-1468	66	3	the	the	DET
admet-1468	66	4	nutrient	nutrient	ADJ
admet-1468	66	5	broth	broth	NOUN
admet-1468	66	6	was	be	AUX
admet-1468	66	7	prepared	prepare	VERB
admet-1468	66	8	and	and	CCONJ
admet-1468	66	9	autoclaved	autoclave	VERB
admet-1468	66	10	for	for	ADP
admet-1468	66	11	20	20	NUM
admet-1468	66	12	minutes	minute	NOUN
admet-1468	66	13	at	at	ADP
admet-1468	66	14	120	120	NUM
admet-1468	66	15	psi	psi	NOUN
admet-1468	66	16	.	.	PUNCT
admet-1468	67	1	cultures	culture	NOUN
admet-1468	67	2	of	of	ADP
admet-1468	67	3	staphylococcus	staphylococcus	NOUN
admet-1468	67	4	aureus	aureus	PROPN
admet-1468	67	5	ncim	ncim	PROPN
admet-1468	67	6	5021	5021	NUM
admet-1468	67	7	and	and	CCONJ
admet-1468	67	8	pseudomonas	pseudomonas	PROPN
admet-1468	67	9	aeruginosa	aeruginosa	PROPN
admet-1468	67	10	ncim	ncim	PROPN
admet-1468	67	11	5029	5029	NUM
admet-1468	67	12	were	be	AUX
admet-1468	67	13	inoculated	inoculate	VERB
admet-1468	67	14	and	and	CCONJ
admet-1468	67	15	incubated	incubate	VERB
admet-1468	67	16	at	at	ADP
admet-1468	67	17	37	37	NUM
admet-1468	67	18	°	°	NOUN
admet-1468	67	19	c	c	NOUN
admet-1468	67	20	for	for	ADP
admet-1468	67	21	24	24	NUM
admet-1468	67	22	hours	hour	NOUN
admet-1468	67	23	.	.	PUNCT
admet-1468	68	1	then	then	ADV
admet-1468	68	2	,	,	PUNCT
admet-1468	68	3	each	each	PRON
admet-1468	68	4	well	well	ADV
admet-1468	68	5	was	be	AUX
admet-1468	68	6	inoculated	inoculate	VERB
admet-1468	68	7	with	with	ADP
admet-1468	68	8	a	a	DET
admet-1468	68	9	microbial	microbial	ADJ
admet-1468	68	10	inoculum	inoculum	NOUN
admet-1468	68	11	prepared	prepare	VERB
admet-1468	68	12	in	in	ADP
admet-1468	68	13	the	the	DET
admet-1468	68	14	same	same	ADJ
admet-1468	68	15	medium	medium	NOUN
admet-1468	68	16	after	after	ADP
admet-1468	68	17	dilution	dilution	NOUN
admet-1468	68	18	of	of	ADP
admet-1468	68	19	standardized	standardized	ADJ
admet-1468	68	20	microbial	microbial	ADJ
admet-1468	68	21	suspension	suspension	NOUN
admet-1468	68	22	adjusted	adjust	VERB
admet-1468	68	23	to	to	ADP
admet-1468	68	24	0.5	0.5	NUM
admet-1468	68	25	mcfarland	mcfarland	NOUN
admet-1468	68	26	scale	scale	NOUN
admet-1468	68	27	(	(	PUNCT
admet-1468	68	28	108	108	NUM
admet-1468	68	29	cfu	cfu	NOUN
admet-1468	68	30	/	/	SYM
admet-1468	68	31	ml	ml	NOUN
admet-1468	68	32	)	)	PUNCT
admet-1468	68	33	.	.	PUNCT
admet-1468	69	1	180	180	NUM
admet-1468	69	2	µl	µl	NOUN
admet-1468	69	3	of	of	ADP
admet-1468	69	4	the	the	DET
admet-1468	69	5	cell	cell	NOUN
admet-1468	69	6	suspension	suspension	NOUN
admet-1468	69	7	was	be	AUX
admet-1468	69	8	seeded	seed	VERB
admet-1468	69	9	in	in	ADP
admet-1468	69	10	each	each	PRON
admet-1468	69	11	of	of	ADP
admet-1468	69	12	the	the	DET
admet-1468	69	13	96	96	NUM
admet-1468	69	14	well	well	ADJ
admet-1468	69	15	plates	plate	NOUN
admet-1468	69	16	and	and	CCONJ
admet-1468	69	17	20	20	NUM
admet-1468	69	18	µl	µl	NOUN
admet-1468	69	19	of	of	ADP
admet-1468	69	20	different	different	ADJ
admet-1468	69	21	concentrations	concentration	NOUN
admet-1468	69	22	of	of	ADP
admet-1468	69	23	the	the	DET
admet-1468	69	24	test	test	NOUN
admet-1468	69	25	compounds	compound	NOUN
admet-1468	69	26	and	and	CCONJ
admet-1468	69	27	the	the	DET
admet-1468	69	28	standard	standard	NOUN
admet-1468	69	29	was	be	AUX
admet-1468	69	30	added	add	VERB
admet-1468	69	31	.	.	PUNCT
admet-1468	70	1	the	the	DET
admet-1468	70	2	wells	well	NOUN
admet-1468	70	3	without	without	ADP
admet-1468	70	4	test	test	NOUN
admet-1468	70	5	compound	compound	NOUN
admet-1468	70	6	were	be	AUX
admet-1468	70	7	considered	consider	VERB
admet-1468	70	8	as	as	SCONJ
admet-1468	70	9	control	control	NOUN
admet-1468	70	10	and	and	CCONJ
admet-1468	70	11	streptomycin	streptomycin	PROPN
admet-1468	70	12	was	be	AUX
admet-1468	70	13	used	use	VERB
admet-1468	70	14	as	as	ADP
admet-1468	70	15	standard	standard	NOUN
admet-1468	70	16	.	.	PUNCT
admet-1468	71	1	after	after	ADP
admet-1468	71	2	mixing	mix	VERB
admet-1468	71	3	,	,	PUNCT
admet-1468	71	4	the	the	DET
admet-1468	71	5	96	96	NUM
admet-1468	71	6	-	-	PUNCT
admet-1468	71	7	well	well	NOUN
admet-1468	71	8	plates	plate	NOUN
admet-1468	71	9	were	be	AUX
admet-1468	71	10	incubated	incubate	VERB
admet-1468	71	11	at	at	ADP
admet-1468	71	12	37	37	NUM
admet-1468	71	13	°	°	NOUN
admet-1468	71	14	c	c	NOUN
admet-1468	71	15	for	for	ADP
admet-1468	71	16	24	24	NUM
admet-1468	71	17	hours	hour	NOUN
admet-1468	71	18	.	.	PUNCT
admet-1468	72	1	after	after	ADP
admet-1468	72	2	incubation	incubation	NOUN
admet-1468	72	3	,	,	PUNCT
admet-1468	72	4	the	the	DET
admet-1468	72	5	absorbance	absorbance	NOUN
admet-1468	72	6	of	of	ADP
admet-1468	72	7	each	each	DET
admet-1468	72	8	well	well	ADV
admet-1468	72	9	was	be	AUX
admet-1468	72	10	recorded	record	VERB
admet-1468	72	11	at	at	ADP
admet-1468	72	12	620	620	NUM
admet-1468	72	13	nm	nm	NOUN
admet-1468	72	14	using	use	VERB
admet-1468	72	15	readwell	readwell	NOUN
admet-1468	72	16	touch	touch	NOUN
admet-1468	72	17	automatic	automatic	ADJ
admet-1468	72	18	elisa	elisa	NOUN
admet-1468	72	19	plate	plate	NOUN
admet-1468	72	20	reader	reader	NOUN
admet-1468	72	21	(	(	PUNCT
admet-1468	72	22	robonik	robonik	VERB
admet-1468	72	23	india	india	PROPN
admet-1468	72	24	private	private	ADJ
admet-1468	72	25	limited	limited	ADJ
admet-1468	72	26	)	)	PUNCT
admet-1468	72	27	.	.	PUNCT
admet-1468	73	1	all	all	DET
admet-1468	73	2	the	the	DET
admet-1468	73	3	experiments	experiment	NOUN
admet-1468	73	4	were	be	AUX
admet-1468	73	5	performed	perform	VERB
admet-1468	73	6	in	in	ADP
admet-1468	73	7	triplicates	triplicate	NOUN
admet-1468	73	8	and	and	CCONJ
admet-1468	73	9	the	the	DET
admet-1468	73	10	growth	growth	NOUN
admet-1468	73	11	percentage	percentage	NOUN
admet-1468	73	12	was	be	AUX
admet-1468	73	13	calculated	calculate	VERB
admet-1468	73	14	using	use	VERB
admet-1468	73	15	the	the	DET
admet-1468	73	16	formula	formula	NOUN
admet-1468	73	17	:	:	PUNCT
admet-1468	73	18	percentage	percentage	NOUN
admet-1468	73	19	growth	growth	NOUN
admet-1468	73	20	inhibition=	inhibition=	NUM
admet-1468	73	21	ti	ti	NOUN
admet-1468	73	22	/	/	SYM
admet-1468	73	23	c	c	NOUN
admet-1468	73	24	x	x	SYM
admet-1468	73	25	100	100	NUM
admet-1468	73	26	where	where	SCONJ
admet-1468	73	27	ti	ti	NOUN
admet-1468	73	28	=	=	SYM
admet-1468	73	29	growth	growth	NOUN
admet-1468	73	30	of	of	ADP
admet-1468	73	31	the	the	DET
admet-1468	73	32	microorganisms	microorganism	NOUN
admet-1468	73	33	in	in	ADP
admet-1468	73	34	the	the	DET
admet-1468	73	35	presence	presence	NOUN
admet-1468	73	36	of	of	ADP
admet-1468	73	37	a	a	DET
admet-1468	73	38	drug	drug	NOUN
admet-1468	73	39	,	,	PUNCT
admet-1468	73	40	and	and	CCONJ
admet-1468	73	41	c	c	X
admet-1468	73	42	=	=	SYM
admet-1468	73	43	control	control	NOUN
admet-1468	73	44	growth	growth	NOUN
admet-1468	73	45	.	.	PUNCT
admet-1468	74	1	a	a	DET
admet-1468	74	2	similar	similar	ADJ
admet-1468	74	3	procedure	procedure	NOUN
admet-1468	74	4	was	be	AUX
admet-1468	74	5	applied	apply	VERB
admet-1468	74	6	for	for	ADP
admet-1468	74	7	the	the	DET
admet-1468	74	8	antifungal	antifungal	ADJ
admet-1468	74	9	activity	activity	NOUN
admet-1468	74	10	test	test	NOUN
admet-1468	74	11	with	with	ADP
admet-1468	74	12	slight	slight	ADJ
admet-1468	74	13	changes	change	NOUN
admet-1468	74	14	.	.	PUNCT
admet-1468	75	1	potato	potato	NOUN
admet-1468	75	2	dextrose	dextrose	NOUN
admet-1468	75	3	broth	broth	NOUN
admet-1468	75	4	(	(	PUNCT
admet-1468	75	5	pdb	pdb	NOUN
admet-1468	75	6	)	)	PUNCT
admet-1468	75	7	was	be	AUX
admet-1468	75	8	used	use	VERB
admet-1468	75	9	for	for	ADP
admet-1468	75	10	fungal	fungal	ADJ
admet-1468	75	11	culture	culture	NOUN
admet-1468	75	12	pre	pre	NOUN
admet-1468	75	13	-	-	NOUN
admet-1468	75	14	enrichment	enrichment	ADJ
admet-1468	75	15	,	,	PUNCT
admet-1468	75	16	dilutions	dilution	NOUN
admet-1468	75	17	and	and	CCONJ
admet-1468	75	18	inoculations	inoculation	NOUN
admet-1468	75	19	.	.	PUNCT
admet-1468	76	1	the	the	DET
admet-1468	76	2	antifungal	antifungal	ADJ
admet-1468	76	3	activity	activity	NOUN
admet-1468	76	4	was	be	AUX
admet-1468	76	5	evaluated	evaluate	VERB
admet-1468	76	6	using	use	VERB
admet-1468	76	7	the	the	DET
admet-1468	76	8	candida	candida	NOUN
admet-1468	76	9	albicans	albican	NOUN
admet-1468	76	10	ncim	ncim	NOUN
admet-1468	76	11	3100	3100	NUM
admet-1468	76	12	strain	strain	NOUN
admet-1468	76	13	.	.	PUNCT
admet-1468	77	1	180	180	NUM
admet-1468	77	2	µl	µl	NOUN
admet-1468	77	3	of	of	ADP
admet-1468	77	4	the	the	DET
admet-1468	77	5	cell	cell	NOUN
admet-1468	77	6	suspension	suspension	NOUN
admet-1468	77	7	was	be	AUX
admet-1468	77	8	seeded	seed	VERB
admet-1468	77	9	in	in	ADP
admet-1468	77	10	each	each	PRON
admet-1468	77	11	of	of	ADP
admet-1468	77	12	the	the	DET
admet-1468	77	13	96	96	NUM
admet-1468	77	14	-	-	PUNCT
admet-1468	77	15	well	well	NOUN
admet-1468	77	16	plates	plate	NOUN
admet-1468	77	17	and	and	CCONJ
admet-1468	77	18	20	20	NUM
admet-1468	77	19	µl	µl	NOUN
admet-1468	77	20	of	of	ADP
admet-1468	77	21	different	different	ADJ
admet-1468	77	22	concentrations	concentration	NOUN
admet-1468	77	23	of	of	ADP
admet-1468	77	24	the	the	DET
admet-1468	77	25	test	test	NOUN
admet-1468	77	26	compounds	compound	NOUN
admet-1468	77	27	and	and	CCONJ
admet-1468	77	28	the	the	DET
admet-1468	77	29	standard	standard	NOUN
admet-1468	77	30	was	be	AUX
admet-1468	77	31	added	add	VERB
admet-1468	77	32	to	to	ADP
admet-1468	77	33	the	the	DET
admet-1468	77	34	respective	respective	ADJ
admet-1468	77	35	wells	well	NOUN
admet-1468	77	36	in	in	ADP
admet-1468	77	37	the	the	DET
admet-1468	77	38	plate	plate	NOUN
admet-1468	77	39	.	.	PUNCT
admet-1468	78	1	the	the	DET
admet-1468	78	2	wells	well	NOUN
admet-1468	78	3	without	without	ADP
admet-1468	78	4	test	test	NOUN
admet-1468	78	5	compound	compound	NOUN
admet-1468	78	6	were	be	AUX
admet-1468	78	7	considered	consider	VERB
admet-1468	78	8	as	as	SCONJ
admet-1468	78	9	control	control	NOUN
admet-1468	78	10	and	and	CCONJ
admet-1468	78	11	itraconazole	itraconazole	NOUN
admet-1468	78	12	was	be	AUX
admet-1468	78	13	used	use	VERB
admet-1468	78	14	as	as	ADP
admet-1468	78	15	standard	standard	NOUN
admet-1468	78	16	.	.	PUNCT
admet-1468	79	1	after	after	ADP
admet-1468	79	2	mixing	mix	VERB
admet-1468	79	3	,	,	PUNCT
admet-1468	79	4	the	the	DET
admet-1468	79	5	96	96	NUM
admet-1468	79	6	-	-	PUNCT
admet-1468	79	7	well	well	NOUN
admet-1468	79	8	plates	plate	NOUN
admet-1468	79	9	were	be	AUX
admet-1468	79	10	incubated	incubate	VERB
admet-1468	79	11	at	at	ADP
admet-1468	79	12	37	37	NUM
admet-1468	79	13	°	°	NOUN
admet-1468	79	14	c	c	NOUN
admet-1468	79	15	for	for	ADP
admet-1468	79	16	24	24	NUM
admet-1468	79	17	hours	hour	NOUN
admet-1468	79	18	.	.	PUNCT
admet-1468	80	1	after	after	ADP
admet-1468	80	2	incubation	incubation	NOUN
admet-1468	80	3	,	,	PUNCT
admet-1468	80	4	the	the	DET
admet-1468	80	5	absorbance	absorbance	NOUN
admet-1468	80	6	of	of	ADP
admet-1468	80	7	each	each	DET
admet-1468	80	8	well	well	ADV
admet-1468	80	9	was	be	AUX
admet-1468	80	10	recorded	record	VERB
admet-1468	80	11	at	at	ADP
admet-1468	80	12	620	620	NUM
admet-1468	80	13	nm	nm	NOUN
admet-1468	80	14	using	use	VERB
admet-1468	80	15	readwell	readwell	NOUN
admet-1468	80	16	touch	touch	NOUN
admet-1468	80	17	automatic	automatic	ADJ
admet-1468	80	18	elisa	elisa	NOUN
admet-1468	80	19	plate	plate	NOUN
admet-1468	80	20	reader	reader	NOUN
admet-1468	80	21	(	(	PUNCT
admet-1468	80	22	robonik	robonik	VERB
admet-1468	80	23	india	india	PROPN
admet-1468	80	24	private	private	ADJ
admet-1468	80	25	limited	limited	ADJ
admet-1468	80	26	)	)	PUNCT
admet-1468	80	27	.	.	PUNCT
admet-1468	81	1	all	all	DET
admet-1468	81	2	the	the	DET
admet-1468	81	3	experiments	experiment	NOUN
admet-1468	81	4	were	be	AUX
admet-1468	81	5	performed	perform	VERB
admet-1468	81	6	in	in	ADP
admet-1468	81	7	triplicates	triplicate	NOUN
admet-1468	81	8	and	and	CCONJ
admet-1468	81	9	the	the	DET
admet-1468	81	10	growth	growth	NOUN
admet-1468	81	11	percentage	percentage	NOUN
admet-1468	81	12	was	be	AUX
admet-1468	81	13	calculated	calculate	VERB
admet-1468	81	14	using	use	VERB
admet-1468	81	15	the	the	DET
admet-1468	81	16	formula	formula	NOUN
admet-1468	81	17	mentioned	mention	VERB
admet-1468	81	18	above	above	ADV
admet-1468	81	19	.	.	PUNCT
admet-1468	82	1	antioxidant	antioxidant	ADJ
admet-1468	82	2	activity	activity	NOUN
admet-1468	82	3	(	(	PUNCT
admet-1468	82	4	dpph	dpph	NOUN
admet-1468	82	5	scavenging	scavenge	VERB
admet-1468	82	6	activity	activity	NOUN
admet-1468	82	7	)	)	PUNCT
admet-1468	82	8	the	the	DET
admet-1468	82	9	dpph	dpph	NOUN
admet-1468	82	10	free	free	ADJ
admet-1468	82	11	radicals	radical	NOUN
admet-1468	82	12	scavenging	scavenge	VERB
admet-1468	82	13	activity	activity	NOUN
admet-1468	82	14	was	be	AUX
admet-1468	82	15	assessed	assess	VERB
admet-1468	82	16	using	use	VERB
admet-1468	82	17	the	the	DET
admet-1468	82	18	microplate	microplate	NOUN
admet-1468	82	19	assay	assay	PROPN
admet-1468	82	20	standard	standard	PROPN
admet-1468	82	21	method	method	NOUN
admet-1468	82	22	with	with	ADP
admet-1468	82	23	slight	slight	ADJ
admet-1468	82	24	modifications	modification	NOUN
admet-1468	82	25	.	.	PUNCT
admet-1468	83	1	drug	drug	NOUN
admet-1468	83	2	stock	stock	NOUN
admet-1468	83	3	solutions	solution	NOUN
admet-1468	83	4	(	(	PUNCT
admet-1468	83	5	1000	1000	NUM
admet-1468	83	6	µg	µg	NOUN
admet-1468	83	7	/	/	SYM
admet-1468	83	8	ml	ml	NOUN
admet-1468	83	9	)	)	PUNCT
admet-1468	83	10	were	be	AUX
admet-1468	83	11	diluted	dilute	VERB
admet-1468	83	12	to	to	ADP
admet-1468	83	13	final	final	ADJ
admet-1468	83	14	concentrations	concentration	NOUN
admet-1468	83	15	of	of	ADP
admet-1468	83	16	1	1	NUM
admet-1468	83	17	,	,	PUNCT
admet-1468	83	18	5	5	NUM
admet-1468	83	19	,	,	PUNCT
admet-1468	83	20	10	10	NUM
admet-1468	83	21	,	,	PUNCT
admet-1468	83	22	20	20	NUM
admet-1468	83	23	,	,	PUNCT
admet-1468	83	24	25	25	NUM
admet-1468	83	25	,	,	PUNCT
admet-1468	83	26	40	40	NUM
admet-1468	83	27	,	,	PUNCT
admet-1468	83	28	50	50	NUM
admet-1468	83	29	,	,	PUNCT
admet-1468	83	30	60	60	NUM
admet-1468	83	31	,	,	PUNCT
admet-1468	83	32	80	80	NUM
admet-1468	83	33	,	,	PUNCT
admet-1468	83	34	100	100	NUM
admet-1468	83	35	,	,	PUNCT
admet-1468	83	36	125	125	NUM
admet-1468	83	37	and	and	CCONJ
admet-1468	83	38	150	150	NUM
admet-1468	83	39	µg	µg	NOUN
admet-1468	83	40	/	/	SYM
admet-1468	83	41	ml	ml	NOUN
admet-1468	83	42	in	in	ADP
admet-1468	83	43	methanol	methanol	NOUN
admet-1468	83	44	.	.	PUNCT
admet-1468	84	1	0.004	0.004	NUM
admet-1468	85	1	g	g	NOUN
admet-1468	85	2	dpph	dpph	NOUN
admet-1468	85	3	reagent	reagent	NOUN
admet-1468	85	4	was	be	AUX
admet-1468	85	5	dissolved	dissolve	VERB
admet-1468	85	6	in	in	ADP
admet-1468	85	7	100	100	NUM
admet-1468	85	8	ml	ml	NOUN
admet-1468	85	9	methanol	methanol	NOUN
admet-1468	85	10	.	.	PUNCT
admet-1468	86	1	50	50	NUM
admet-1468	86	2	µl	µl	NOUN
admet-1468	86	3	of	of	ADP
admet-1468	86	4	the	the	DET
admet-1468	86	5	sample	sample	NOUN
admet-1468	86	6	and	and	CCONJ
admet-1468	86	7	150	150	NUM
admet-1468	86	8	µl	µl	NOUN
admet-1468	86	9	of	of	ADP
admet-1468	86	10	the	the	DET
admet-1468	86	11	dpph	dpph	NOUN
admet-1468	86	12	solution	solution	NOUN
admet-1468	86	13	were	be	AUX
admet-1468	86	14	added	add	VERB
admet-1468	86	15	to	to	ADP
admet-1468	86	16	96	96	NUM
admet-1468	86	17	well	well	ADJ
admet-1468	86	18	plates	plate	NOUN
admet-1468	86	19	.	.	PUNCT
admet-1468	87	1	the	the	DET
admet-1468	87	2	plate	plate	NOUN
admet-1468	87	3	was	be	AUX
admet-1468	87	4	incubated	incubate	VERB
admet-1468	87	5	for	for	ADP
admet-1468	87	6	30	30	NUM
admet-1468	87	7	min	min	NOUN
admet-1468	87	8	at	at	ADP
admet-1468	87	9	room	room	NOUN
admet-1468	87	10	temperature	temperature	NOUN
admet-1468	87	11	in	in	ADP
admet-1468	87	12	the	the	DET
admet-1468	87	13	dark	dark	NOUN
admet-1468	87	14	.	.	PUNCT
admet-1468	88	1	the	the	DET
admet-1468	88	2	absorbance	absorbance	NOUN
admet-1468	88	3	(	(	PUNCT
admet-1468	88	4	abs	ab	NOUN
admet-1468	88	5	)	)	PUNCT
admet-1468	88	6	was	be	AUX
admet-1468	88	7	recorded	record	VERB
admet-1468	88	8	at	at	ADP
admet-1468	88	9	520	520	NUM
admet-1468	88	10	nm	nm	ADJ
admet-1468	88	11	wavelength	wavelength	NOUN
admet-1468	88	12	with	with	ADP
admet-1468	88	13	a	a	DET
admet-1468	88	14	microplate	microplate	NOUN
admet-1468	88	15	reader	reader	NOUN
admet-1468	88	16	(	(	PUNCT
admet-1468	88	17	readwell	readwell	PROPN
admet-1468	88	18	touch	touch	NOUN
admet-1468	88	19	automatic	automatic	ADJ
admet-1468	88	20	elisa	elisa	NOUN
admet-1468	88	21	plate	plate	NOUN
admet-1468	88	22	reader	reader	NOUN
admet-1468	88	23	(	(	PUNCT
admet-1468	88	24	robonik	robonik	VERB
admet-1468	88	25	india	india	PROPN
admet-1468	88	26	private	private	ADJ
admet-1468	88	27	limited	limited	ADJ
admet-1468	88	28	)	)	PUNCT
admet-1468	88	29	and	and	CCONJ
admet-1468	88	30	converted	convert	VERB
admet-1468	88	31	to	to	ADP
admet-1468	88	32	the	the	DET
admet-1468	88	33	percentages	percentage	NOUN
admet-1468	88	34	.	.	PUNCT
admet-1468	89	1	methanol	methanol	NOUN
admet-1468	89	2	was	be	AUX
admet-1468	89	3	used	use	VERB
admet-1468	89	4	as	as	ADP
admet-1468	89	5	a	a	DET
admet-1468	89	6	solvent	solvent	NOUN
admet-1468	89	7	and	and	CCONJ
admet-1468	89	8	ascorbic	ascorbic	NOUN
admet-1468	89	9	acid	acid	NOUN
admet-1468	89	10	as	as	ADP
admet-1468	89	11	standard	standard	NOUN
admet-1468	89	12	.	.	PUNCT
admet-1468	90	1	the	the	DET
admet-1468	90	2	percentage	percentage	NOUN
admet-1468	90	3	radical	radical	ADJ
admet-1468	90	4	scavenging	scavenging	NOUN
admet-1468	90	5	was	be	AUX
admet-1468	90	6	calculated	calculate	VERB
admet-1468	90	7	from	from	ADP
admet-1468	90	8	the	the	DET
admet-1468	90	9	absorbance	absorbance	NOUN
admet-1468	90	10	using	use	VERB
admet-1468	90	11	the	the	DET
admet-1468	90	12	following	follow	VERB
admet-1468	90	13	formula	formula	NOUN
admet-1468	90	14	:	:	PUNCT
admet-1468	90	15	%	%	NOUN
admet-1468	90	16	radical	radical	ADJ
admet-1468	90	17	scavenging	scavenge	VERB
admet-1468	90	18	activity	activity	NOUN
admet-1468	90	19	=	=	SYM
admet-1468	90	20	(	(	PUNCT
admet-1468	90	21	(	(	PUNCT
admet-1468	90	22	abs	ab	NOUN
admet-1468	90	23	of	of	ADP
admet-1468	90	24	control	control	NOUN
admet-1468	90	25	-	-	PUNCT
admet-1468	90	26	abs	ab	NOUN
admet-1468	90	27	of	of	ADP
admet-1468	90	28	sample))/(abs	sample))/(abs	PROPN
admet-1468	90	29	of	of	ADP
admet-1468	90	30	control	control	NOUN
admet-1468	90	31	)	)	PUNCT
admet-1468	90	32	x	x	SYM
admet-1468	90	33	100	100	NUM
admet-1468	90	34	cell	cell	NOUN
admet-1468	90	35	viability	viability	NOUN
admet-1468	90	36	inhibition	inhibition	NOUN
admet-1468	90	37	assay	assay	NOUN
admet-1468	90	38	(	(	PUNCT
admet-1468	90	39	mtt	mtt	NOUN
admet-1468	90	40	assay	assay	VERB
admet-1468	90	41	)	)	PUNCT
admet-1468	90	42	the	the	DET
admet-1468	90	43	in	in	ADV
admet-1468	90	44	vitro	vitro	X
admet-1468	90	45	antiproliferative	antiproliferative	ADJ
admet-1468	90	46	activities	activity	NOUN
admet-1468	90	47	of	of	ADP
admet-1468	90	48	the	the	DET
admet-1468	90	49	test	test	NOUN
admet-1468	90	50	compounds	compound	NOUN
admet-1468	90	51	were	be	AUX
admet-1468	90	52	evaluated	evaluate	VERB
admet-1468	90	53	against	against	ADP
admet-1468	90	54	five	five	NUM
admet-1468	90	55	human	human	ADJ
admet-1468	90	56	cancer	cancer	NOUN
admet-1468	90	57	cell	cell	NOUN
admet-1468	90	58	lines	line	NOUN
admet-1468	90	59	,	,	PUNCT
admet-1468	90	60	which	which	PRON
admet-1468	90	61	include	include	VERB
admet-1468	90	62	two	two	NUM
admet-1468	90	63	human	human	ADJ
admet-1468	90	64	breast	breast	NOUN
admet-1468	90	65	cancer	cancer	NOUN
admet-1468	90	66	cell	cell	NOUN
admet-1468	90	67	lines	line	NOUN
admet-1468	90	68	(	(	PUNCT
admet-1468	90	69	mcf-7	mcf-7	X
admet-1468	90	70	and	and	CCONJ
admet-1468	90	71	mda	mda	PROPN
admet-1468	90	72	-	-	PUNCT
admet-1468	90	73	mb-231	mb-231	PROPN
admet-1468	90	74	)	)	PUNCT
admet-1468	90	75	,	,	PUNCT
admet-1468	90	76	two	two	NUM
admet-1468	90	77	human	human	ADJ
admet-1468	90	78	colon	colon	NOUN
admet-1468	90	79	carcinoma	carcinoma	NOUN
admet-1468	90	80	cell	cell	NOUN
admet-1468	90	81	lines	line	NOUN
admet-1468	90	82	(	(	PUNCT
admet-1468	90	83	colo-205	colo-205	NOUN
admet-1468	90	84	and	and	CCONJ
admet-1468	90	85	ht-29	ht-29	NUM
admet-1468	90	86	)	)	PUNCT
admet-1468	90	87	,	,	PUNCT
admet-1468	90	88	and	and	CCONJ
admet-1468	90	89	one	one	NUM
admet-1468	90	90	human	human	ADJ
admet-1468	90	91	lung	lung	NOUN
admet-1468	90	92	carcinoma	carcinoma	NOUN
admet-1468	90	93	(	(	PUNCT
admet-1468	90	94	a549	a549	PROPN
admet-1468	90	95	)	)	PUNCT
admet-1468	90	96	using	use	VERB
admet-1468	90	97	the	the	DET
admet-1468	90	98	mtt	mtt	NOUN
admet-1468	90	99	assay	assay	VERB
admet-1468	90	100	.	.	PUNCT
admet-1468	91	1	5fluorouracil	5fluorouracil	NUM
admet-1468	91	2	(	(	PUNCT
admet-1468	91	3	5	5	NUM
admet-1468	91	4	-	-	PUNCT
admet-1468	91	5	fu	fu	NOUN
admet-1468	91	6	)	)	PUNCT
admet-1468	91	7	was	be	AUX
admet-1468	91	8	used	use	VERB
admet-1468	91	9	as	as	ADP
admet-1468	91	10	a	a	DET
admet-1468	91	11	positive	positive	ADJ
admet-1468	91	12	control	control	NOUN
admet-1468	91	13	.	.	PUNCT
admet-1468	92	1	the	the	DET
admet-1468	92	2	tested	test	VERB
admet-1468	92	3	cell	cell	NOUN
admet-1468	92	4	lines	line	NOUN
admet-1468	92	5	were	be	AUX
admet-1468	92	6	purchased	purchase	VERB
admet-1468	92	7	from	from	ADP
admet-1468	92	8	the	the	DET
admet-1468	92	9	national	national	ADJ
admet-1468	92	10	centre	centre	NOUN
admet-1468	92	11	for	for	ADP
admet-1468	92	12	cell	cell	NOUN
admet-1468	92	13	science	science	NOUN
admet-1468	92	14	(	(	PUNCT
admet-1468	92	15	nccs	nccs	PROPN
admet-1468	92	16	)	)	PUNCT
admet-1468	92	17	,	,	PUNCT
admet-1468	92	18	pune	pune	NOUN
admet-1468	92	19	,	,	PUNCT
admet-1468	92	20	and	and	CCONJ
admet-1468	92	21	cultivated	cultivate	VERB
admet-1468	92	22	in	in	ADP
admet-1468	92	23	the	the	DET
admet-1468	92	24	appropriate	appropriate	ADJ
admet-1468	92	25	growth	growth	NOUN
admet-1468	92	26	medium	medium	NOUN
admet-1468	92	27	.	.	PUNCT
admet-1468	93	1	the	the	DET
admet-1468	93	2	growth	growth	NOUN
admet-1468	93	3	medium	medium	NOUN
admet-1468	93	4	was	be	AUX
admet-1468	93	5	supplemented	supplement	VERB
admet-1468	93	6	with	with	ADP
admet-1468	93	7	100	100	NUM
admet-1468	93	8	mg	mg	NUM
admet-1468	93	9	/	/	SYM
admet-1468	93	10	ml	ml	PROPN
admet-1468	93	11	of	of	ADP
admet-1468	93	12	streptomycin	streptomycin	PROPN
admet-1468	93	13	,	,	PUNCT
admet-1468	93	14	100	100	NUM
admet-1468	93	15	units	unit	NOUN
admet-1468	93	16	/	/	SYM
admet-1468	93	17	ml	ml	NOUN
admet-1468	93	18	of	of	ADP
admet-1468	93	19	penicillin	penicillin	NOUN
admet-1468	93	20	,	,	PUNCT
admet-1468	93	21	and	and	CCONJ
admet-1468	93	22	10	10	NUM
admet-1468	93	23	%	%	NOUN
admet-1468	93	24	of	of	ADP
admet-1468	93	25	heat	heat	NOUN
admet-1468	93	26	-	-	PUNCT
admet-1468	93	27	inactivated	inactivate	VERB
admet-1468	93	28	fetal	fetal	ADJ
admet-1468	93	29	bovine	bovine	NOUN
admet-1468	93	30	serum	serum	NOUN
admet-1468	93	31	in	in	ADP
admet-1468	93	32	a	a	DET
admet-1468	93	33	humidified	humidified	ADJ
admet-1468	93	34	5	5	NUM
admet-1468	93	35	%	%	NOUN
admet-1468	93	36	(	(	PUNCT
admet-1468	93	37	v	v	NOUN
admet-1468	93	38	/	/	SYM
admet-1468	93	39	v	v	NOUN
admet-1468	93	40	)	)	PUNCT
admet-1468	93	41	co2	co2	NOUN
admet-1468	93	42	atmosphere	atmosphere	NOUN
admet-1468	93	43	at	at	ADP
admet-1468	93	44	37	37	NUM
admet-1468	93	45	°	°	NOUN
admet-1468	93	46	c	c	NOUN
admet-1468	93	47	.	.	PUNCT
admet-1468	94	1	then	then	ADV
admet-1468	94	2	1x106	1x106	NUM
admet-1468	94	3	cells	cell	NOUN
admet-1468	94	4	per	per	ADP
admet-1468	94	5	well	well	ADV
admet-1468	94	6	were	be	AUX
admet-1468	94	7	seeded	seed	VERB
admet-1468	94	8	admet	admet	PROPN
admet-1468	94	9	&	&	CCONJ
admet-1468	94	10	dmpk	dmpk	PROPN
admet-1468	94	11	11(1	11(1	NUM
admet-1468	94	12	)	)	PUNCT
admet-1468	94	13	(	(	PUNCT
admet-1468	94	14	2023	2023	NUM
admet-1468	94	15	)	)	PUNCT
admet-1468	94	16	81	81	NUM
admet-1468	94	17	-	-	SYM
admet-1468	94	18	96	96	NUM
admet-1468	94	19	coumarin	coumarin	NOUN
admet-1468	94	20	-	-	PUNCT
admet-1468	94	21	quinone	quinone	NOUN
admet-1468	94	22	hybrids	hybrid	NOUN
admet-1468	94	23	doi	doi	NOUN
admet-1468	94	24	:	:	PUNCT
admet-1468	94	25	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	94	26	85	85	NUM
admet-1468	94	27	into	into	ADP
admet-1468	94	28	96	96	NUM
admet-1468	94	29	-	-	PUNCT
admet-1468	94	30	well	well	NOUN
admet-1468	94	31	well	well	INTJ
admet-1468	94	32	plates	plate	NOUN
admet-1468	94	33	.	.	PUNCT
admet-1468	95	1	the	the	DET
admet-1468	95	2	medium	medium	NOUN
admet-1468	95	3	was	be	AUX
admet-1468	95	4	replaced	replace	VERB
admet-1468	95	5	after	after	ADP
admet-1468	95	6	24	24	NUM
admet-1468	95	7	-	-	SYM
admet-1468	95	8	48	48	NUM
admet-1468	95	9	hours	hour	NOUN
admet-1468	95	10	with	with	ADP
admet-1468	95	11	a	a	DET
admet-1468	95	12	fresh	fresh	ADJ
admet-1468	95	13	medium	medium	NOUN
admet-1468	95	14	containing	contain	VERB
admet-1468	95	15	different	different	ADJ
admet-1468	95	16	dilutions	dilution	NOUN
admet-1468	95	17	of	of	ADP
admet-1468	95	18	the	the	DET
admet-1468	95	19	test	test	NOUN
admet-1468	95	20	compounds	compound	NOUN
admet-1468	95	21	(	(	PUNCT
admet-1468	95	22	diluted	dilute	VERB
admet-1468	95	23	using	use	VERB
admet-1468	95	24	the	the	DET
admet-1468	95	25	dmem	dmem	NOUN
admet-1468	95	26	)	)	PUNCT
admet-1468	95	27	.	.	PUNCT
admet-1468	96	1	after	after	ADP
admet-1468	96	2	48	48	NUM
admet-1468	96	3	hours	hour	NOUN
admet-1468	96	4	,	,	PUNCT
admet-1468	96	5	5	5	NUM
admet-1468	96	6	%	%	NOUN
admet-1468	96	7	mtt	mtt	NOUN
admet-1468	96	8	solution	solution	NOUN
admet-1468	96	9	was	be	AUX
admet-1468	96	10	added	add	VERB
admet-1468	96	11	.	.	PUNCT
admet-1468	97	1	after	after	ADP
admet-1468	97	2	incubation	incubation	NOUN
admet-1468	97	3	for	for	ADP
admet-1468	97	4	additional	additional	ADJ
admet-1468	97	5	4	4	NUM
admet-1468	97	6	hours	hour	NOUN
admet-1468	97	7	,	,	PUNCT
admet-1468	97	8	the	the	DET
admet-1468	97	9	formazan	formazan	NOUN
admet-1468	97	10	formed	form	VERB
admet-1468	97	11	by	by	ADP
admet-1468	97	12	metabolically	metabolically	ADV
admet-1468	97	13	viable	viable	ADJ
admet-1468	97	14	cells	cell	NOUN
admet-1468	97	15	was	be	AUX
admet-1468	97	16	dissolved	dissolve	VERB
admet-1468	97	17	in	in	ADP
admet-1468	97	18	dmso	dmso	NOUN
admet-1468	97	19	,	,	PUNCT
admet-1468	97	20	and	and	CCONJ
admet-1468	97	21	after	after	ADP
admet-1468	97	22	10	10	NUM
admet-1468	97	23	-	-	SYM
admet-1468	97	24	20	20	NUM
admet-1468	97	25	minutes	minute	NOUN
admet-1468	97	26	,	,	PUNCT
admet-1468	97	27	absorbance	absorbance	NOUN
admet-1468	97	28	was	be	AUX
admet-1468	97	29	recorded	record	VERB
admet-1468	97	30	at	at	ADP
admet-1468	97	31	570	570	NUM
admet-1468	97	32	nm	nm	NOUN
admet-1468	97	33	using	use	VERB
admet-1468	97	34	readwell	readwell	NOUN
admet-1468	97	35	touch	touch	NOUN
admet-1468	97	36	automatic	automatic	ADJ
admet-1468	97	37	elisa	elisa	NOUN
admet-1468	97	38	plate	plate	NOUN
admet-1468	97	39	reader	reader	NOUN
admet-1468	97	40	(	(	PUNCT
admet-1468	97	41	robonik	robonik	VERB
admet-1468	97	42	india	india	PROPN
admet-1468	97	43	private	private	ADJ
admet-1468	97	44	limited	limited	ADJ
admet-1468	97	45	)	)	PUNCT
admet-1468	97	46	.	.	PUNCT
admet-1468	98	1	the	the	DET
admet-1468	98	2	metabolic	metabolic	NOUN
admet-1468	98	3	viability	viability	NOUN
admet-1468	98	4	of	of	ADP
admet-1468	98	5	cancer	cancer	NOUN
admet-1468	98	6	cells	cell	NOUN
admet-1468	98	7	treated	treat	VERB
admet-1468	98	8	with	with	ADP
admet-1468	98	9	test	test	NOUN
admet-1468	98	10	compounds	compound	NOUN
admet-1468	98	11	was	be	AUX
admet-1468	98	12	compared	compare	VERB
admet-1468	98	13	with	with	ADP
admet-1468	98	14	the	the	DET
admet-1468	98	15	viability	viability	NOUN
admet-1468	98	16	of	of	ADP
admet-1468	98	17	untreated	untreated	ADJ
admet-1468	98	18	cells	cell	NOUN
admet-1468	98	19	(	(	PUNCT
admet-1468	98	20	taken	take	VERB
admet-1468	98	21	as	as	ADP
admet-1468	98	22	100	100	NUM
admet-1468	98	23	%	%	NOUN
admet-1468	98	24	viable	viable	ADJ
admet-1468	98	25	)	)	PUNCT
admet-1468	98	26	.	.	PUNCT
admet-1468	99	1	all	all	DET
admet-1468	99	2	experiments	experiment	NOUN
admet-1468	99	3	were	be	AUX
admet-1468	99	4	performed	perform	VERB
admet-1468	99	5	in	in	ADP
admet-1468	99	6	triplicates	triplicate	NOUN
admet-1468	99	7	and	and	CCONJ
admet-1468	99	8	the	the	DET
admet-1468	99	9	growth	growth	NOUN
admet-1468	99	10	percentage	percentage	NOUN
admet-1468	99	11	was	be	AUX
admet-1468	99	12	calculated	calculate	VERB
admet-1468	99	13	using	use	VERB
admet-1468	99	14	the	the	DET
admet-1468	99	15	formula	formula	NOUN
admet-1468	99	16	:	:	PUNCT
admet-1468	99	17	percentage	percentage	NOUN
admet-1468	99	18	growth	growth	NOUN
admet-1468	100	1	inhibition=	inhibition=	NUM
admet-1468	100	2	ti	ti	NOUN
admet-1468	100	3	/	/	SYM
admet-1468	100	4	c	c	NOUN
admet-1468	100	5	x	x	SYM
admet-1468	100	6	100	100	NUM
admet-1468	100	7	where	where	SCONJ
admet-1468	100	8	,	,	PUNCT
admet-1468	100	9	ti	ti	NOUN
admet-1468	100	10	=	=	NOUN
admet-1468	100	11	growth	growth	NOUN
admet-1468	100	12	of	of	ADP
admet-1468	100	13	the	the	DET
admet-1468	100	14	microorganisms	microorganism	NOUN
admet-1468	100	15	in	in	ADP
admet-1468	100	16	the	the	DET
admet-1468	100	17	presence	presence	NOUN
admet-1468	100	18	of	of	ADP
admet-1468	100	19	test	test	NOUN
admet-1468	100	20	compound	compound	NOUN
admet-1468	100	21	and	and	CCONJ
admet-1468	100	22	c	c	NOUN
admet-1468	100	23	=	=	SYM
admet-1468	100	24	control	control	NOUN
admet-1468	100	25	growth	growth	NOUN
admet-1468	100	26	.	.	PUNCT
admet-1468	101	1	in	in	ADP
admet-1468	101	2	vitro	vitro	X
admet-1468	101	3	cytotoxicity	cytotoxicity	NOUN
admet-1468	101	4	assay	assay	VERB
admet-1468	101	5	against	against	ADP
admet-1468	101	6	non	non	ADJ
admet-1468	101	7	-	-	ADJ
admet-1468	101	8	cancerous	cancerous	ADJ
admet-1468	101	9	cells	cell	NOUN
admet-1468	101	10	to	to	PART
admet-1468	101	11	study	study	VERB
admet-1468	101	12	the	the	DET
admet-1468	101	13	toxicity	toxicity	NOUN
admet-1468	101	14	against	against	ADP
admet-1468	101	15	non	non	ADJ
admet-1468	101	16	-	-	ADJ
admet-1468	101	17	malignant	malignant	ADJ
admet-1468	101	18	cells	cell	NOUN
admet-1468	101	19	,	,	PUNCT
admet-1468	101	20	the	the	DET
admet-1468	101	21	compounds	compound	NOUN
admet-1468	101	22	were	be	AUX
admet-1468	101	23	tested	test	VERB
admet-1468	101	24	against	against	ADP
admet-1468	101	25	non	non	ADJ
admet-1468	101	26	-	-	ADJ
admet-1468	101	27	cancerous	cancerous	ADJ
admet-1468	101	28	normal	normal	ADJ
admet-1468	101	29	human	human	ADJ
admet-1468	101	30	peripheral	peripheral	ADJ
admet-1468	101	31	blood	blood	NOUN
admet-1468	101	32	mononuclear	mononuclear	ADJ
admet-1468	101	33	cells	cell	NOUN
admet-1468	101	34	(	(	PUNCT
admet-1468	101	35	pbmcs	pbmcs	NOUN
admet-1468	101	36	)	)	PUNCT
admet-1468	101	37	.	.	PUNCT
admet-1468	102	1	isolation	isolation	NOUN
admet-1468	102	2	of	of	ADP
admet-1468	102	3	peripheral	peripheral	ADJ
admet-1468	102	4	blood	blood	NOUN
admet-1468	102	5	mononuclear	mononuclear	ADJ
admet-1468	102	6	cells	cell	NOUN
admet-1468	102	7	was	be	AUX
admet-1468	102	8	done	do	VERB
admet-1468	102	9	using	use	VERB
admet-1468	102	10	ficoll	ficoll	NOUN
admet-1468	102	11	-	-	PUNCT
admet-1468	102	12	hypaque	hypaque	NOUN
admet-1468	102	13	according	accord	VERB
admet-1468	102	14	to	to	ADP
admet-1468	102	15	the	the	DET
admet-1468	102	16	standard	standard	ADJ
admet-1468	102	17	method	method	NOUN
admet-1468	102	18	[	[	X
admet-1468	102	19	33	33	NUM
admet-1468	102	20	]	]	PUNCT
admet-1468	102	21	and	and	CCONJ
admet-1468	102	22	an	an	DET
admet-1468	102	23	mtt	mtt	NOUN
admet-1468	102	24	assay	assay	NOUN
admet-1468	102	25	was	be	AUX
admet-1468	102	26	used	use	VERB
admet-1468	102	27	to	to	PART
admet-1468	102	28	evaluate	evaluate	VERB
admet-1468	102	29	the	the	DET
admet-1468	102	30	cytotoxicity	cytotoxicity	NOUN
admet-1468	102	31	of	of	ADP
admet-1468	102	32	the	the	DET
admet-1468	102	33	synthesized	synthesize	VERB
admet-1468	102	34	hydrazones	hydrazone	NOUN
admet-1468	102	35	.	.	PUNCT
admet-1468	103	1	1×106	1×106	NUM
admet-1468	103	2	cells	cell	NOUN
admet-1468	103	3	per	per	ADP
admet-1468	103	4	well	well	ADV
admet-1468	103	5	were	be	AUX
admet-1468	103	6	seeded	seed	VERB
admet-1468	103	7	in	in	ADP
admet-1468	103	8	a	a	DET
admet-1468	103	9	96	96	NUM
admet-1468	103	10	-	-	PUNCT
admet-1468	103	11	well	well	NOUN
admet-1468	103	12	plate	plate	NOUN
admet-1468	103	13	before	before	SCONJ
admet-1468	103	14	they	they	PRON
admet-1468	103	15	were	be	AUX
admet-1468	103	16	exposed	expose	VERB
admet-1468	103	17	to	to	ADP
admet-1468	103	18	different	different	ADJ
admet-1468	103	19	concentrations	concentration	NOUN
admet-1468	103	20	of	of	ADP
admet-1468	103	21	tested	test	VERB
admet-1468	103	22	compounds	compound	NOUN
admet-1468	103	23	for	for	ADP
admet-1468	103	24	48	48	NUM
admet-1468	103	25	hrs	hrs	NOUN
admet-1468	103	26	along	along	ADP
admet-1468	103	27	with	with	ADP
admet-1468	103	28	a	a	DET
admet-1468	103	29	control	control	NOUN
admet-1468	103	30	well	well	ADV
admet-1468	103	31	.	.	PUNCT
admet-1468	104	1	after	after	ADP
admet-1468	104	2	48	48	NUM
admet-1468	104	3	hrs	hrs	NOUN
admet-1468	104	4	,	,	PUNCT
admet-1468	104	5	the	the	DET
admet-1468	104	6	culture	culture	NOUN
admet-1468	104	7	medium	medium	NOUN
admet-1468	104	8	containing	contain	VERB
admet-1468	104	9	hydrazones	hydrazone	NOUN
admet-1468	104	10	was	be	AUX
admet-1468	104	11	removed	remove	VERB
admet-1468	104	12	by	by	ADP
admet-1468	104	13	washing	wash	VERB
admet-1468	104	14	with	with	ADP
admet-1468	104	15	pbs	pbs	PROPN
admet-1468	104	16	.	.	PUNCT
admet-1468	105	1	then	then	ADV
admet-1468	105	2	10	10	NUM
admet-1468	105	3	μl	μl	NOUN
admet-1468	105	4	of	of	ADP
admet-1468	105	5	mtt	mtt	NOUN
admet-1468	105	6	solution	solution	NOUN
admet-1468	105	7	(	(	PUNCT
admet-1468	105	8	5mg	5mg	NOUN
admet-1468	105	9	/	/	SYM
admet-1468	105	10	ml	ml	NOUN
admet-1468	105	11	)	)	PUNCT
admet-1468	105	12	was	be	AUX
admet-1468	105	13	added	add	VERB
admet-1468	105	14	and	and	CCONJ
admet-1468	105	15	incubated	incubate	VERB
admet-1468	105	16	for	for	ADP
admet-1468	105	17	4	4	NUM
admet-1468	105	18	hours	hour	NOUN
admet-1468	105	19	,	,	PUNCT
admet-1468	105	20	followed	follow	VERB
admet-1468	105	21	by	by	ADP
admet-1468	105	22	the	the	DET
admet-1468	105	23	addition	addition	NOUN
admet-1468	105	24	of	of	ADP
admet-1468	105	25	100	100	NUM
admet-1468	105	26	μl	μl	ADP
admet-1468	105	27	of	of	ADP
admet-1468	105	28	dmso	dmso	NOUN
admet-1468	105	29	.	.	PUNCT
admet-1468	106	1	after	after	ADP
admet-1468	106	2	10	10	NUM
admet-1468	106	3	-	-	SYM
admet-1468	106	4	20	20	NUM
admet-1468	106	5	minutes	minute	NOUN
admet-1468	106	6	,	,	PUNCT
admet-1468	106	7	absorbance	absorbance	NOUN
admet-1468	106	8	was	be	AUX
admet-1468	106	9	recorded	record	VERB
admet-1468	106	10	at	at	ADP
admet-1468	106	11	570	570	NUM
admet-1468	106	12	nm	nm	NOUN
admet-1468	106	13	using	use	VERB
admet-1468	106	14	readwell	readwell	NOUN
admet-1468	106	15	touch	touch	NOUN
admet-1468	106	16	automatic	automatic	ADJ
admet-1468	106	17	elisa	elisa	NOUN
admet-1468	106	18	plate	plate	NOUN
admet-1468	106	19	reader	reader	NOUN
admet-1468	106	20	(	(	PUNCT
admet-1468	106	21	robonik	robonik	VERB
admet-1468	106	22	india	india	PROPN
admet-1468	106	23	private	private	ADJ
admet-1468	106	24	limited	limited	ADJ
admet-1468	106	25	)	)	PUNCT
admet-1468	106	26	.	.	PUNCT
admet-1468	107	1	furthermore	furthermore	ADV
admet-1468	107	2	,	,	PUNCT
admet-1468	107	3	the	the	DET
admet-1468	107	4	selectivity	selectivity	NOUN
admet-1468	107	5	index	index	NOUN
admet-1468	107	6	was	be	AUX
admet-1468	107	7	calculated	calculate	VERB
admet-1468	107	8	by	by	ADP
admet-1468	107	9	using	use	VERB
admet-1468	107	10	the	the	DET
admet-1468	107	11	following	follow	VERB
admet-1468	107	12	formula	formula	NOUN
admet-1468	107	13	.	.	PUNCT
admet-1468	108	1	selectivity	selectivity	NOUN
admet-1468	108	2	index	index	NOUN
admet-1468	108	3	=	=	SYM
admet-1468	108	4	ic50	ic50	PROPN
admet-1468	108	5	value	value	NOUN
admet-1468	108	6	from	from	ADP
admet-1468	108	7	pbmc	pbmc	NOUN
admet-1468	108	8	/	/	SYM
admet-1468	108	9	ic50	ic50	PROPN
admet-1468	108	10	value	value	NOUN
admet-1468	108	11	of	of	ADP
admet-1468	108	12	the	the	DET
admet-1468	108	13	same	same	ADJ
admet-1468	108	14	compound	compound	NOUN
admet-1468	108	15	in	in	ADP
admet-1468	108	16	cancer	cancer	NOUN
admet-1468	108	17	cells	cell	NOUN
admet-1468	108	18	molecular	molecular	ADJ
admet-1468	108	19	docking	dock	VERB
admet-1468	108	20	molecular	molecular	ADJ
admet-1468	108	21	docking	docking	NOUN
admet-1468	108	22	studies	study	NOUN
admet-1468	108	23	were	be	AUX
admet-1468	108	24	carried	carry	VERB
admet-1468	108	25	out	out	ADP
admet-1468	108	26	with	with	ADP
admet-1468	108	27	the	the	DET
admet-1468	108	28	cox-2	cox-2	ADJ
admet-1468	108	29	protein	protein	NOUN
admet-1468	108	30	model	model	NOUN
admet-1468	108	31	[	[	X
admet-1468	108	32	34	34	NUM
admet-1468	108	33	]	]	PUNCT
admet-1468	108	34	.	.	PUNCT
admet-1468	109	1	essential	essential	ADJ
admet-1468	109	2	hydrogen	hydrogen	NOUN
admet-1468	109	3	atoms	atom	NOUN
admet-1468	109	4	,	,	PUNCT
admet-1468	109	5	kollman	kollman	NOUN
admet-1468	109	6	united	united	PROPN
admet-1468	109	7	atom	atom	PROPN
admet-1468	109	8	type	type	NOUN
admet-1468	109	9	charges	charge	NOUN
admet-1468	109	10	and	and	CCONJ
admet-1468	109	11	salvation	salvation	NOUN
admet-1468	109	12	parameters	parameter	NOUN
admet-1468	109	13	were	be	AUX
admet-1468	109	14	added	add	VERB
admet-1468	109	15	with	with	ADP
admet-1468	109	16	the	the	DET
admet-1468	109	17	aid	aid	NOUN
admet-1468	109	18	of	of	ADP
admet-1468	109	19	autodock	autodock	NOUN
admet-1468	109	20	4.2	4.2	NUM
admet-1468	109	21	tools	tool	NOUN
admet-1468	109	22	.	.	PUNCT
admet-1468	110	1	molecular	molecular	ADJ
admet-1468	110	2	docking	docking	NOUN
admet-1468	110	3	was	be	AUX
admet-1468	110	4	conducted	conduct	VERB
admet-1468	110	5	in	in	ADP
admet-1468	110	6	these	these	DET
admet-1468	110	7	protein	protein	NOUN
admet-1468	110	8	cavities	cavity	NOUN
admet-1468	110	9	by	by	ADP
admet-1468	110	10	using	use	VERB
admet-1468	110	11	autodock	autodock	PROPN
admet-1468	110	12	vina	vina	PROPN
admet-1468	110	13	.	.	PUNCT
admet-1468	111	1	auto	auto	PROPN
admet-1468	111	2	dock	dock	NOUN
admet-1468	111	3	4.2	4.2	NUM
admet-1468	111	4	(	(	PUNCT
admet-1468	111	5	mgl	mgl	PROPN
admet-1468	111	6	tools1.5.6	tools1.5.6	PROPN
admet-1468	111	7	)	)	PUNCT
admet-1468	111	8	was	be	AUX
admet-1468	111	9	used	use	VERB
admet-1468	111	10	to	to	PART
admet-1468	111	11	perform	perform	VERB
admet-1468	111	12	all	all	DET
admet-1468	111	13	docking	docking	NOUN
admet-1468	111	14	calculations	calculation	NOUN
admet-1468	111	15	,	,	PUNCT
admet-1468	111	16	and	and	CCONJ
admet-1468	111	17	finally	finally	ADV
admet-1468	111	18	,	,	PUNCT
admet-1468	111	19	pymol	pymol	PROPN
admet-1468	111	20	viewer	viewer	NOUN
admet-1468	111	21	was	be	AUX
admet-1468	111	22	used	use	VERB
admet-1468	111	23	to	to	PART
admet-1468	111	24	visualize	visualize	VERB
admet-1468	111	25	docking	docking	NOUN
admet-1468	111	26	results	result	NOUN
admet-1468	111	27	.	.	PUNCT
admet-1468	112	1	admet	admet	NOUN
admet-1468	112	2	and	and	CCONJ
admet-1468	112	3	pharmacokinetic	pharmacokinetic	ADJ
admet-1468	112	4	studies	study	NOUN
admet-1468	112	5	admet	admet	ADJ
admet-1468	112	6	and	and	CCONJ
admet-1468	112	7	pharmacokinetic	pharmacokinetic	ADJ
admet-1468	112	8	properties	property	NOUN
admet-1468	112	9	were	be	AUX
admet-1468	112	10	determined	determine	VERB
admet-1468	112	11	using	use	VERB
admet-1468	112	12	pkcsm	pkcsm	NOUN
admet-1468	112	13	(	(	PUNCT
admet-1468	112	14	a	a	DET
admet-1468	112	15	cambridge	cambridge	PROPN
admet-1468	112	16	online	online	PROPN
admet-1468	112	17	source	source	PROPN
admet-1468	112	18	,	,	PUNCT
admet-1468	112	19	link	link	NOUN
admet-1468	112	20	:	:	PUNCT
admet-1468	112	21	http://biosig.unimelb.edu.au/pkcsm/prediction	http://biosig.unimelb.edu.au/pkcsm/prediction	NOUN
admet-1468	112	22	)	)	PUNCT
admet-1468	112	23	.	.	PUNCT
admet-1468	113	1	the	the	DET
admet-1468	113	2	structures	structure	NOUN
admet-1468	113	3	of	of	ADP
admet-1468	113	4	all	all	DET
admet-1468	113	5	test	test	NOUN
admet-1468	113	6	compounds	compound	NOUN
admet-1468	113	7	and	and	CCONJ
admet-1468	113	8	their	their	PRON
admet-1468	113	9	physicochemical	physicochemical	ADJ
admet-1468	113	10	properties	property	NOUN
admet-1468	113	11	were	be	AUX
admet-1468	113	12	drawn	draw	VERB
admet-1468	113	13	and	and	CCONJ
admet-1468	113	14	calculated	calculate	VERB
admet-1468	113	15	using	use	VERB
admet-1468	113	16	chemdraw	chemdraw	PROPN
admet-1468	113	17	12.0	12.0	NUM
admet-1468	113	18	software	software	NOUN
admet-1468	113	19	.	.	PUNCT
admet-1468	114	1	simultaneously	simultaneously	ADV
admet-1468	114	2	,	,	PUNCT
admet-1468	114	3	the	the	DET
admet-1468	114	4	smile	smile	ADJ
admet-1468	114	5	file	file	NOUN
admet-1468	114	6	format	format	NOUN
admet-1468	114	7	of	of	ADP
admet-1468	114	8	all	all	DET
admet-1468	114	9	compounds	compound	NOUN
admet-1468	114	10	was	be	AUX
admet-1468	114	11	obtained	obtain	VERB
admet-1468	114	12	from	from	ADP
admet-1468	114	13	chemdraw	chemdraw	NOUN
admet-1468	114	14	12.0	12.0	NUM
admet-1468	114	15	to	to	PART
admet-1468	114	16	obtain	obtain	VERB
admet-1468	114	17	the	the	DET
admet-1468	114	18	drug	drug	NOUN
admet-1468	114	19	-	-	PUNCT
admet-1468	114	20	likeness	likeness	NOUN
admet-1468	114	21	data	datum	NOUN
admet-1468	114	22	.	.	PUNCT
admet-1468	115	1	pkcsm	pkcsm	NOUN
admet-1468	115	2	predictor	predictor	NOUN
admet-1468	115	3	provides	provide	VERB
admet-1468	115	4	information	information	NOUN
admet-1468	115	5	regarding	regard	VERB
admet-1468	115	6	absorption	absorption	NOUN
admet-1468	115	7	parameters	parameter	NOUN
admet-1468	115	8	like	like	ADP
admet-1468	115	9	human	human	ADJ
admet-1468	115	10	intestinal	intestinal	ADJ
admet-1468	115	11	absorption	absorption	NOUN
admet-1468	115	12	(	(	PUNCT
admet-1468	115	13	hia	hia	PROPN
admet-1468	115	14	)	)	PUNCT
admet-1468	115	15	,	,	PUNCT
admet-1468	115	16	oral	oral	ADJ
admet-1468	115	17	bioavailability	bioavailability	NOUN
admet-1468	115	18	,	,	PUNCT
admet-1468	115	19	caco-2	caco-2	NUM
admet-1468	115	20	permeability	permeability	NOUN
admet-1468	115	21	,	,	PUNCT
admet-1468	115	22	distribution	distribution	NOUN
admet-1468	115	23	parameters	parameter	NOUN
admet-1468	115	24	like	like	ADP
admet-1468	115	25	plasma	plasma	NOUN
admet-1468	115	26	protein	protein	NOUN
admet-1468	115	27	binding	bind	VERB
admet-1468	115	28	(	(	PUNCT
admet-1468	115	29	ppb	ppb	NOUN
admet-1468	115	30	)	)	PUNCT
admet-1468	115	31	,	,	PUNCT
admet-1468	115	32	blood	blood	NOUN
admet-1468	115	33	-	-	PUNCT
admet-1468	115	34	brain	brain	NOUN
admet-1468	115	35	barrier	barrier	NOUN
admet-1468	115	36	(	(	PUNCT
admet-1468	115	37	bbb	bbb	NOUN
admet-1468	115	38	)	)	PUNCT
admet-1468	115	39	,	,	PUNCT
admet-1468	115	40	metabolism	metabolism	NOUN
admet-1468	115	41	parameters	parameter	NOUN
admet-1468	115	42	like	like	ADP
admet-1468	115	43	cytochrome	cytochrome	NOUN
admet-1468	115	44	p450	p450	NUM
admet-1468	115	45	2d6	2d6	NUM
admet-1468	115	46	(	(	PUNCT
admet-1468	115	47	cyp2d6	cyp2d6	NOUN
admet-1468	115	48	)	)	PUNCT
admet-1468	115	49	inhibition	inhibition	NOUN
admet-1468	115	50	and	and	CCONJ
admet-1468	115	51	cytochrome	cytochrome	ADJ
admet-1468	115	52	p450	p450	NUM
admet-1468	115	53	3a4	3a4	NUM
admet-1468	115	54	(	(	PUNCT
admet-1468	115	55	cyp3a4	cyp3a4	NOUN
admet-1468	115	56	)	)	PUNCT
admet-1468	115	57	inhibition	inhibition	NOUN
admet-1468	115	58	,	,	PUNCT
admet-1468	115	59	excretion	excretion	NOUN
admet-1468	115	60	parameters	parameter	NOUN
admet-1468	115	61	like	like	ADP
admet-1468	115	62	renal	renal	ADJ
admet-1468	115	63	clearance	clearance	NOUN
admet-1468	115	64	,	,	PUNCT
admet-1468	115	65	and	and	CCONJ
admet-1468	115	66	toxicity	toxicity	NOUN
admet-1468	115	67	parameters	parameter	NOUN
admet-1468	115	68	like	like	ADP
admet-1468	115	69	organ	organ	NOUN
admet-1468	115	70	toxicity	toxicity	NOUN
admet-1468	115	71	and	and	CCONJ
admet-1468	115	72	genomic	genomic	ADJ
admet-1468	115	73	toxicities	toxicity	NOUN
admet-1468	115	74	.	.	PUNCT
admet-1468	116	1	the	the	DET
admet-1468	116	2	pharmacological	pharmacological	ADJ
admet-1468	116	3	properties	property	NOUN
admet-1468	116	4	and	and	CCONJ
admet-1468	116	5	drug	drug	NOUN
admet-1468	116	6	-	-	PUNCT
admet-1468	116	7	likeness	likeness	NOUN
admet-1468	116	8	of	of	ADP
admet-1468	116	9	the	the	DET
admet-1468	116	10	test	test	NOUN
admet-1468	116	11	compounds	compound	NOUN
admet-1468	116	12	were	be	AUX
admet-1468	116	13	evaluated	evaluate	VERB
admet-1468	116	14	using	use	VERB
admet-1468	116	15	the	the	DET
admet-1468	116	16	online	online	ADJ
admet-1468	116	17	source	source	NOUN
admet-1468	116	18	swissadme	swissadme	NOUN
admet-1468	116	19	(	(	PUNCT
admet-1468	116	20	link	link	NOUN
admet-1468	116	21	:	:	PUNCT
admet-1468	116	22	http://www.swissadme.ch/	http://www.swissadme.ch/	NUM
admet-1468	116	23	)	)	PUNCT
admet-1468	116	24	.	.	PUNCT
admet-1468	117	1	results	result	NOUN
admet-1468	117	2	and	and	CCONJ
admet-1468	117	3	discussion	discussion	NOUN
admet-1468	117	4	chemistry	chemistry	NOUN
admet-1468	117	5	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	117	6	http://biosig.unimelb.edu.au/pkcsm/prediction	http://biosig.unimelb.edu.au/pkcsm/prediction	PROPN
admet-1468	117	7	http://www.swissadme.ch/	http://www.swissadme.ch/	VERB
admet-1468	117	8	a.	a.	NOUN
admet-1468	117	9	pangal	pangal	PROPN
admet-1468	117	10	and	and	CCONJ
admet-1468	117	11	k.	k.	PROPN
admet-1468	117	12	ahmed	ahmed	PROPN
admet-1468	117	13	admet	admet	PROPN
admet-1468	117	14	&	&	CCONJ
admet-1468	117	15	dmpk	dmpk	PROPN
admet-1468	117	16	11(1	11(1	NUM
admet-1468	117	17	)	)	PUNCT
admet-1468	117	18	(	(	PUNCT
admet-1468	117	19	2023	2023	NUM
admet-1468	117	20	)	)	PUNCT
admet-1468	117	21	81	81	NUM
admet-1468	117	22	-	-	SYM
admet-1468	117	23	96	96	NUM
admet-1468	117	24	86	86	NUM
admet-1468	117	25	the	the	DET
admet-1468	117	26	target	target	NOUN
admet-1468	117	27	compounds	compound	NOUN
admet-1468	117	28	were	be	AUX
admet-1468	117	29	synthesized	synthesize	VERB
admet-1468	117	30	in	in	ADP
admet-1468	117	31	two	two	NUM
admet-1468	117	32	steps	step	NOUN
admet-1468	117	33	,	,	PUNCT
admet-1468	117	34	as	as	SCONJ
admet-1468	117	35	shown	show	VERB
admet-1468	117	36	in	in	ADP
admet-1468	117	37	figure	figure	NOUN
admet-1468	117	38	1	1	NUM
admet-1468	117	39	.	.	PUNCT
admet-1468	117	40	initially	initially	ADV
admet-1468	117	41	,	,	PUNCT
admet-1468	117	42	2,6	2,6	NUM
admet-1468	117	43	-	-	ADJ
admet-1468	117	44	di	di	NOUN
admet-1468	117	45	-	-	PUNCT
admet-1468	117	46	tert	tert	NOUN
admet-1468	117	47	-	-	PUNCT
admet-1468	117	48	butyl-1,4benzoquinone	butyl-1,4benzoquinone	NOUN
admet-1468	117	49	hydrazone	hydrazone	NOUN
admet-1468	117	50	(	(	PUNCT
admet-1468	117	51	3	3	NUM
admet-1468	117	52	)	)	PUNCT
admet-1468	117	53	was	be	AUX
admet-1468	117	54	prepared	prepare	VERB
admet-1468	117	55	from	from	ADP
admet-1468	117	56	the	the	DET
admet-1468	117	57	reaction	reaction	NOUN
admet-1468	117	58	of	of	ADP
admet-1468	117	59	2,6	2,6	NUM
admet-1468	117	60	-	-	ADJ
admet-1468	117	61	di	di	NOUN
admet-1468	117	62	-	-	PUNCT
admet-1468	117	63	tert	tert	NOUN
admet-1468	117	64	-	-	PUNCT
admet-1468	117	65	butyl-1,4	butyl-1,4	NOUN
admet-1468	117	66	-	-	PUNCT
admet-1468	117	67	benzoquinone	benzoquinone	NOUN
admet-1468	117	68	(	(	PUNCT
admet-1468	117	69	1	1	NUM
admet-1468	117	70	)	)	PUNCT
admet-1468	117	71	with	with	ADP
admet-1468	117	72	ethyl	ethyl	PROPN
admet-1468	117	73	3	3	PROPN
admet-1468	117	74	-	-	PUNCT
admet-1468	117	75	hydrazinyl-3	hydrazinyl-3	NOUN
admet-1468	117	76	-	-	PUNCT
admet-1468	117	77	oxopropanoate	oxopropanoate	NOUN
admet-1468	117	78	(	(	PUNCT
admet-1468	117	79	2	2	NUM
admet-1468	117	80	)	)	PUNCT
admet-1468	117	81	.	.	PUNCT
admet-1468	118	1	the	the	DET
admet-1468	118	2	intermediate	intermediate	ADJ
admet-1468	118	3	(	(	PUNCT
admet-1468	118	4	3	3	NUM
admet-1468	118	5	)	)	PUNCT
admet-1468	118	6	was	be	AUX
admet-1468	118	7	obtained	obtain	VERB
admet-1468	118	8	as	as	ADP
admet-1468	118	9	a	a	DET
admet-1468	118	10	yellow	yellow	ADJ
admet-1468	118	11	compound	compound	NOUN
admet-1468	118	12	in	in	ADP
admet-1468	118	13	high	high	ADJ
admet-1468	118	14	yield	yield	NOUN
admet-1468	118	15	.	.	PUNCT
admet-1468	119	1	the	the	DET
admet-1468	119	2	structure	structure	NOUN
admet-1468	119	3	of	of	ADP
admet-1468	119	4	(	(	PUNCT
admet-1468	119	5	3	3	X
admet-1468	119	6	)	)	PUNCT
admet-1468	119	7	was	be	AUX
admet-1468	119	8	confirmed	confirm	VERB
admet-1468	119	9	based	base	VERB
admet-1468	119	10	on	on	ADP
admet-1468	119	11	its	its	PRON
admet-1468	119	12	hrms	hrm	NOUN
admet-1468	119	13	,	,	PUNCT
admet-1468	119	14	ir	ir	PROPN
admet-1468	119	15	,	,	PUNCT
admet-1468	119	16	1h	1h	NUM
admet-1468	119	17	-	-	PUNCT
admet-1468	119	18	nmr	nmr	NOUN
admet-1468	119	19	and	and	CCONJ
admet-1468	119	20	13c	13c	NOUN
admet-1468	119	21	-	-	ADJ
admet-1468	119	22	nmr	nmr	ADJ
admet-1468	119	23	spectra	spectra	NOUN
admet-1468	119	24	.	.	PUNCT
admet-1468	120	1	subsequently	subsequently	ADV
admet-1468	120	2	,	,	PUNCT
admet-1468	120	3	the	the	DET
admet-1468	120	4	coumarin	coumarin	NOUN
admet-1468	120	5	-	-	PUNCT
admet-1468	120	6	quinone	quinone	NOUN
admet-1468	120	7	hybrids	hybrid	NOUN
admet-1468	120	8	(	(	PUNCT
admet-1468	120	9	5	5	NUM
admet-1468	120	10	)	)	PUNCT
admet-1468	120	11	were	be	AUX
admet-1468	120	12	obtained	obtain	VERB
admet-1468	120	13	from	from	ADP
admet-1468	120	14	(	(	PUNCT
admet-1468	120	15	3	3	NUM
admet-1468	120	16	)	)	PUNCT
admet-1468	120	17	and	and	CCONJ
admet-1468	120	18	the	the	DET
admet-1468	120	19	corresponding	corresponding	ADJ
admet-1468	120	20	salicylaldehyde	salicylaldehyde	NOUN
admet-1468	120	21	(	(	PUNCT
admet-1468	120	22	4	4	NUM
admet-1468	120	23	)	)	PUNCT
admet-1468	120	24	in	in	ADP
admet-1468	120	25	the	the	DET
admet-1468	120	26	presence	presence	NOUN
admet-1468	120	27	of	of	ADP
admet-1468	120	28	a	a	DET
admet-1468	120	29	few	few	ADJ
admet-1468	120	30	drops	drop	NOUN
admet-1468	120	31	of	of	ADP
admet-1468	120	32	piperidine	piperidine	NOUN
admet-1468	120	33	,	,	PUNCT
admet-1468	120	34	followed	follow	VERB
admet-1468	120	35	by	by	ADP
admet-1468	120	36	neutralization	neutralization	NOUN
admet-1468	120	37	with	with	ADP
admet-1468	120	38	diluted	diluted	ADJ
admet-1468	120	39	hcl	hcl	PROPN
admet-1468	120	40	.	.	PUNCT
admet-1468	121	1	four	four	NUM
admet-1468	121	2	coumarin	coumarin	NOUN
admet-1468	121	3	-	-	PUNCT
admet-1468	121	4	quinone	quinone	NOUN
admet-1468	121	5	hybrids	hybrid	NOUN
admet-1468	121	6	abbreviated	abbreviate	VERB
admet-1468	121	7	as	as	ADP
admet-1468	121	8	dtbsa	dtbsa	NOUN
admet-1468	121	9	,	,	PUNCT
admet-1468	121	10	dtbsc	dtbsc	NOUN
admet-1468	121	11	,	,	PUNCT
admet-1468	121	12	dtbsb	dtbsb	NOUN
admet-1468	121	13	and	and	CCONJ
admet-1468	121	14	dtbsn	dtbsn	NOUN
admet-1468	121	15	were	be	AUX
admet-1468	121	16	obtained	obtain	VERB
admet-1468	121	17	and	and	CCONJ
admet-1468	121	18	purified	purify	VERB
admet-1468	121	19	,	,	PUNCT
admet-1468	121	20	followed	follow	VERB
admet-1468	121	21	by	by	ADP
admet-1468	121	22	characterization	characterization	NOUN
admet-1468	121	23	using	use	VERB
admet-1468	121	24	hrms	hrm	NOUN
admet-1468	121	25	,	,	PUNCT
admet-1468	121	26	ftir	ftir	PROPN
admet-1468	121	27	,	,	PUNCT
admet-1468	121	28	1h	1h	NUM
admet-1468	121	29	-	-	PUNCT
admet-1468	121	30	nmr	nmr	NOUN
admet-1468	121	31	and	and	CCONJ
admet-1468	121	32	13c	13c	NOUN
admet-1468	121	33	-	-	ADJ
admet-1468	121	34	nmr	nmr	NOUN
admet-1468	121	35	spectroscopy	spectroscopy	NOUN
admet-1468	121	36	.	.	PUNCT
admet-1468	122	1	the	the	DET
admet-1468	122	2	hrms	hrm	NOUN
admet-1468	122	3	(	(	PUNCT
admet-1468	122	4	ei	ei	NOUN
admet-1468	122	5	)	)	PUNCT
admet-1468	122	6	spectra	spectra	NOUN
admet-1468	122	7	of	of	ADP
admet-1468	122	8	all	all	DET
admet-1468	122	9	coumarin	coumarin	NOUN
admet-1468	122	10	-	-	PUNCT
admet-1468	122	11	quinone	quinone	NOUN
admet-1468	122	12	hybrids	hybrid	NOUN
admet-1468	122	13	showed	show	VERB
admet-1468	122	14	the	the	DET
admet-1468	122	15	major	major	ADJ
admet-1468	122	16	peaks	peak	NOUN
admet-1468	122	17	corresponding	correspond	VERB
admet-1468	122	18	to	to	ADP
admet-1468	122	19	the	the	DET
admet-1468	122	20	expected	expect	VERB
admet-1468	122	21	m+1	m+1	NUM
admet-1468	122	22	or	or	CCONJ
admet-1468	122	23	m+h	m+h	ADJ
admet-1468	122	24	fragment	fragment	NOUN
admet-1468	122	25	at	at	ADP
admet-1468	122	26	407.20	407.20	NUM
admet-1468	122	27	,	,	PUNCT
admet-1468	122	28	441.16	441.16	NUM
admet-1468	122	29	,	,	PUNCT
admet-1468	122	30	485.11	485.11	NUM
admet-1468	122	31	and	and	CCONJ
admet-1468	122	32	452.18	452.18	NUM
admet-1468	122	33	,	,	PUNCT
admet-1468	122	34	respectively	respectively	ADV
admet-1468	122	35	.	.	PUNCT
admet-1468	123	1	the	the	DET
admet-1468	123	2	ir	ir	PROPN
admet-1468	123	3	spectra	spectra	NOUN
admet-1468	123	4	of	of	ADP
admet-1468	123	5	these	these	DET
admet-1468	123	6	analogs	analog	NOUN
admet-1468	123	7	showed	show	VERB
admet-1468	123	8	characteristic	characteristic	ADJ
admet-1468	123	9	peaks	peak	NOUN
admet-1468	123	10	for	for	ADP
admet-1468	123	11	–	–	PUNCT
admet-1468	123	12	nh	nh	PROPN
admet-1468	123	13	,	,	PUNCT
admet-1468	123	14	lactone	lactone	NOUN
admet-1468	123	15	carbonyl	carbonyl	NOUN
admet-1468	123	16	and	and	CCONJ
admet-1468	123	17	>	>	X
admet-1468	123	18	c	c	X
admet-1468	123	19	=	=	X
admet-1468	123	20	o	o	X
admet-1468	123	21	(	(	PUNCT
admet-1468	123	22	amide	amide	NOUN
admet-1468	123	23	)	)	PUNCT
admet-1468	123	24	.	.	PUNCT
admet-1468	124	1	the	the	DET
admet-1468	124	2	ir	ir	PROPN
admet-1468	124	3	spectrum	spectrum	NOUN
admet-1468	124	4	of	of	ADP
admet-1468	124	5	all	all	DET
admet-1468	124	6	analogs	analog	NOUN
admet-1468	124	7	showed	show	VERB
admet-1468	124	8	one	one	NUM
admet-1468	124	9	peak	peak	NOUN
admet-1468	124	10	between	between	ADP
admet-1468	124	11	3739.30	3739.30	NUM
admet-1468	124	12	to	to	ADP
admet-1468	124	13	3745.08	3745.08	NUM
admet-1468	124	14	cm-1	cm-1	NOUN
admet-1468	124	15	for	for	ADP
admet-1468	124	16	–	–	PUNCT
admet-1468	124	17	nh	nh	PROPN
admet-1468	124	18	.	.	PUNCT
admet-1468	125	1	the	the	DET
admet-1468	125	2	peaks	peak	NOUN
admet-1468	125	3	at	at	ADP
admet-1468	125	4	1712	1712	NUM
admet-1468	125	5	to	to	ADP
admet-1468	125	6	1714	1714	NUM
admet-1468	125	7	cm-1	cm-1	VERB
admet-1468	125	8	is	be	AUX
admet-1468	125	9	due	due	ADJ
admet-1468	125	10	to	to	PART
admet-1468	125	11	>	>	PUNCT
admet-1468	125	12	c	c	PROPN
admet-1468	125	13	=	=	X
admet-1468	125	14	o	o	X
admet-1468	125	15	(	(	PUNCT
admet-1468	125	16	lactone	lactone	PROPN
admet-1468	125	17	moiety	moiety	PROPN
admet-1468	125	18	)	)	PUNCT
admet-1468	125	19	and	and	CCONJ
admet-1468	125	20	at	at	ADP
admet-1468	125	21	1624.73	1624.73	NUM
admet-1468	125	22	to	to	ADP
admet-1468	125	23	1683.55	1683.55	NUM
admet-1468	125	24	cm-1	cm-1	VERB
admet-1468	125	25	are	be	AUX
admet-1468	125	26	amide	amide	NOUN
admet-1468	125	27	>	>	PUNCT
admet-1468	125	28	c	c	X
admet-1468	125	29	=	=	NOUN
admet-1468	125	30	o.	o.	NOUN
admet-1468	125	31	the	the	DET
admet-1468	125	32	peak	peak	NOUN
admet-1468	125	33	for	for	ADP
admet-1468	125	34	the	the	DET
admet-1468	125	35	imine	imine	NOUN
admet-1468	125	36	group	group	NOUN
admet-1468	125	37	was	be	AUX
admet-1468	125	38	detected	detect	VERB
admet-1468	125	39	between	between	ADP
admet-1468	125	40	1525	1525	NUM
admet-1468	125	41	to	to	ADP
admet-1468	125	42	1536	1536	NUM
admet-1468	125	43	cm-1	cm-1	NOUN
admet-1468	125	44	.	.	PUNCT
admet-1468	126	1	the	the	DET
admet-1468	126	2	1h	1h	NUM
admet-1468	126	3	-	-	PUNCT
admet-1468	126	4	nmr	nmr	NOUN
admet-1468	126	5	spectra	spectra	NOUN
admet-1468	126	6	of	of	ADP
admet-1468	126	7	the	the	DET
admet-1468	126	8	hybrid	hybrid	ADJ
admet-1468	126	9	compounds	compound	NOUN
admet-1468	126	10	showed	show	VERB
admet-1468	126	11	the	the	DET
admet-1468	126	12	olefin	olefin	ADJ
admet-1468	126	13	proton	proton	NOUN
admet-1468	126	14	of	of	ADP
admet-1468	126	15	the	the	DET
admet-1468	126	16	coumarin	coumarin	NOUN
admet-1468	126	17	ring	ring	NOUN
admet-1468	126	18	as	as	ADP
admet-1468	126	19	a	a	DET
admet-1468	126	20	sharp	sharp	ADJ
admet-1468	126	21	singlet	singlet	NOUN
admet-1468	126	22	at	at	ADP
admet-1468	126	23	9.06	9.06	NUM
admet-1468	126	24	to	to	PART
admet-1468	126	25	9.5	9.5	NUM
admet-1468	126	26	ppm	ppm	NOUN
admet-1468	126	27	.	.	PUNCT
admet-1468	127	1	the	the	DET
admet-1468	127	2	amide	amide	NOUN
admet-1468	127	3	protons	proton	NOUN
admet-1468	127	4	appeared	appear	VERB
admet-1468	127	5	as	as	ADP
admet-1468	127	6	singlet	singlet	NOUN
admet-1468	127	7	from	from	ADP
admet-1468	127	8	10	10	NUM
admet-1468	127	9	to	to	PART
admet-1468	127	10	12.78	12.78	NUM
admet-1468	127	11	ppm	ppm	NOUN
admet-1468	127	12	.	.	PUNCT
admet-1468	128	1	the	the	DET
admet-1468	128	2	13c	13c	NOUN
admet-1468	128	3	-	-	NOUN
admet-1468	128	4	nmr	nmr	NOUN
admet-1468	128	5	of	of	ADP
admet-1468	128	6	all	all	DET
admet-1468	128	7	these	these	DET
admet-1468	128	8	analogs	analog	NOUN
admet-1468	128	9	exhibited	exhibit	VERB
admet-1468	128	10	signals	signal	NOUN
admet-1468	128	11	for	for	ADP
admet-1468	128	12	all	all	DET
admet-1468	128	13	aromatic	aromatic	ADJ
admet-1468	128	14	carbon	carbon	NOUN
admet-1468	128	15	atoms	atom	NOUN
admet-1468	128	16	in	in	ADP
admet-1468	128	17	the	the	DET
admet-1468	128	18	estimated	estimate	VERB
admet-1468	128	19	range	range	NOUN
admet-1468	128	20	and	and	CCONJ
admet-1468	128	21	characteristic	characteristic	ADJ
admet-1468	128	22	peaks	peak	NOUN
admet-1468	128	23	of	of	ADP
admet-1468	128	24	imine	imine	NOUN
admet-1468	128	25	,	,	PUNCT
admet-1468	128	26	lactone	lactone	NOUN
admet-1468	128	27	carbonyl	carbonyl	NOUN
admet-1468	128	28	,	,	PUNCT
admet-1468	128	29	amide	amide	NOUN
admet-1468	128	30	and	and	CCONJ
admet-1468	128	31	ketone	ketone	NOUN
admet-1468	128	32	carbonyl	carbonyl	NOUN
admet-1468	128	33	carbons	carbon	NOUN
admet-1468	128	34	in	in	ADP
admet-1468	128	35	the	the	DET
admet-1468	128	36	range	range	NOUN
admet-1468	128	37	of	of	ADP
admet-1468	128	38	153	153	NUM
admet-1468	128	39	-	-	SYM
admet-1468	128	40	154	154	NUM
admet-1468	128	41	,	,	PUNCT
admet-1468	128	42	157	157	NUM
admet-1468	128	43	-	-	SYM
admet-1468	128	44	159	159	NUM
admet-1468	128	45	,	,	PUNCT
admet-1468	128	46	165	165	NUM
admet-1468	128	47	-	-	SYM
admet-1468	128	48	167	167	NUM
admet-1468	128	49	and	and	CCONJ
admet-1468	128	50	186	186	NUM
admet-1468	128	51	ppm	ppm	NOUN
admet-1468	128	52	,	,	PUNCT
admet-1468	128	53	respectively	respectively	ADV
admet-1468	128	54	.	.	PUNCT
admet-1468	129	1	o	o	NOUN
admet-1468	130	1	n	n	PRON
admet-1468	130	2	h	h	NOUN
admet-1468	131	1	o	o	X
admet-1468	131	2	ch3	ch3	PROPN
admet-1468	131	3	o	o	X
admet-1468	131	4	o	o	X
admet-1468	131	5	cf3cooh	cf3cooh	X
admet-1468	131	6	etoh	etoh	PROPN
admet-1468	131	7	,	,	PUNCT
admet-1468	131	8	rt	rt	PROPN
admet-1468	131	9	1	1	NUM
admet-1468	131	10	h2n	h2n	PROPN
admet-1468	131	11	o	o	NOUN
admet-1468	131	12	n	n	CCONJ
admet-1468	131	13	o	o	NOUN
admet-1468	132	1	n	n	PRON
admet-1468	132	2	h	h	NOUN
admet-1468	133	1	o	o	NOUN
admet-1468	133	2	o	o	X
admet-1468	134	1	o	o	X
admet-1468	135	1	+	+	CCONJ
admet-1468	135	2	n	n	CCONJ
admet-1468	135	3	o	o	NOUN
admet-1468	135	4	n	n	PRON
admet-1468	136	1	h	h	NOUN
admet-1468	137	1	o	o	NOUN
admet-1468	137	2	o	o	X
admet-1468	137	3	o	o	X
admet-1468	137	4	ho	ho	ADJ
admet-1468	137	5	piperidine	piperidine	NOUN
admet-1468	137	6	etoh	etoh	NOUN
admet-1468	137	7	,	,	PUNCT
admet-1468	137	8	rt	rt	NOUN
admet-1468	137	9	o	o	NOUN
admet-1468	138	1	n	n	CCONJ
admet-1468	138	2	h	h	NOUN
admet-1468	139	1	o	o	NOUN
admet-1468	139	2	o	o	INTJ
admet-1468	140	1	h	h	NOUN
admet-1468	141	1	o	o	NOUN
admet-1468	141	2	x	x	PUNCT
admet-1468	142	1	+	+	CCONJ
admet-1468	142	2	x	x	SYM
admet-1468	142	3	n	n	NUM
admet-1468	142	4	o	o	NOUN
admet-1468	142	5	3	3	NUM
admet-1468	142	6	dtbsa	dtbsa	NOUN
admet-1468	142	7	where	where	SCONJ
admet-1468	142	8	x	x	SYM
admet-1468	142	9	=	=	SYM
admet-1468	142	10	dtbsc	dtbsc	PROPN
admet-1468	142	11	dtbsb	dtbsb	NOUN
admet-1468	142	12	-no2	-no2	INTJ
admet-1468	142	13	-	-	PUNCT
admet-1468	142	14	br	br	ADP
admet-1468	142	15	-	-	PUNCT
admet-1468	142	16	cl	cl	NOUN
admet-1468	142	17	-	-	PUNCT
admet-1468	142	18	h	h	NOUN
admet-1468	142	19	dtbsn	dtbsn	NOUN
admet-1468	142	20	2	2	NUM
admet-1468	142	21	3	3	NUM
admet-1468	142	22	4	4	NUM
admet-1468	142	23	5	5	NUM
admet-1468	142	24	figure	figure	NOUN
admet-1468	142	25	1	1	NUM
admet-1468	142	26	.	.	PUNCT
admet-1468	142	27	synthesis	synthesis	NOUN
admet-1468	142	28	of	of	ADP
admet-1468	142	29	coumarin	coumarin	NOUN
admet-1468	142	30	-	-	PUNCT
admet-1468	142	31	quinone	quinone	NOUN
admet-1468	142	32	hybrids	hybrid	NOUN
admet-1468	142	33	(	(	PUNCT
admet-1468	142	34	5	5	NUM
admet-1468	142	35	)	)	PUNCT
admet-1468	142	36	antimicrobial	antimicrobial	ADJ
admet-1468	142	37	activity	activity	NOUN
admet-1468	142	38	the	the	DET
admet-1468	142	39	coumarin	coumarin	NOUN
admet-1468	142	40	-	-	PUNCT
admet-1468	142	41	quinone	quinone	NOUN
admet-1468	142	42	hybrids	hybrid	NOUN
admet-1468	142	43	(	(	PUNCT
admet-1468	142	44	5	5	NUM
admet-1468	142	45	)	)	PUNCT
admet-1468	142	46	were	be	AUX
admet-1468	142	47	tested	test	VERB
admet-1468	142	48	for	for	ADP
admet-1468	142	49	their	their	PRON
admet-1468	142	50	antimicrobial	antimicrobial	ADJ
admet-1468	142	51	activity	activity	NOUN
admet-1468	142	52	using	use	VERB
admet-1468	142	53	staphylococcus	staphylococcus	NOUN
admet-1468	142	54	aureus	aureus	PROPN
admet-1468	142	55	ncim	ncim	PROPN
admet-1468	142	56	5021	5021	NUM
admet-1468	142	57	,	,	PUNCT
admet-1468	142	58	pseudomonas	pseudomonas	PROPN
admet-1468	142	59	aeruginosa	aeruginosa	PROPN
admet-1468	142	60	ncim	ncim	PROPN
admet-1468	142	61	5029	5029	NUM
admet-1468	142	62	and	and	CCONJ
admet-1468	142	63	candida	candida	PROPN
admet-1468	142	64	albicans	albican	VERB
admet-1468	142	65	ncim	ncim	NOUN
admet-1468	142	66	3100	3100	NUM
admet-1468	142	67	strains	strain	NOUN
admet-1468	142	68	.	.	PUNCT
admet-1468	143	1	different	different	ADJ
admet-1468	143	2	concentrations	concentration	NOUN
admet-1468	143	3	of	of	ADP
admet-1468	143	4	the	the	DET
admet-1468	143	5	hybrids	hybrid	NOUN
admet-1468	143	6	were	be	AUX
admet-1468	143	7	used	use	VERB
admet-1468	143	8	for	for	ADP
admet-1468	143	9	screening	screen	VERB
admet-1468	143	10	.	.	PUNCT
admet-1468	144	1	the	the	DET
admet-1468	144	2	obtained	obtain	VERB
admet-1468	144	3	results	result	NOUN
admet-1468	144	4	were	be	AUX
admet-1468	144	5	compared	compare	VERB
admet-1468	144	6	with	with	ADP
admet-1468	144	7	the	the	DET
admet-1468	144	8	values	value	NOUN
admet-1468	144	9	produced	produce	VERB
admet-1468	144	10	from	from	ADP
admet-1468	144	11	the	the	DET
admet-1468	144	12	standard	standard	ADJ
admet-1468	144	13	drugs	drug	NOUN
admet-1468	144	14	streptomycin	streptomycin	PROPN
admet-1468	144	15	(	(	PUNCT
admet-1468	144	16	antibacterial	antibacterial	ADJ
admet-1468	144	17	)	)	PUNCT
admet-1468	144	18	and	and	CCONJ
admet-1468	144	19	itraconazole	itraconazole	NOUN
admet-1468	144	20	(	(	PUNCT
admet-1468	144	21	antifungal	antifungal	PROPN
admet-1468	144	22	)	)	PUNCT
admet-1468	144	23	.	.	PUNCT
admet-1468	145	1	growth	growth	NOUN
admet-1468	145	2	curves	curve	NOUN
admet-1468	145	3	are	be	AUX
admet-1468	145	4	shown	show	VERB
admet-1468	145	5	in	in	ADP
admet-1468	145	6	figure	figure	NOUN
admet-1468	145	7	2	2	NUM
admet-1468	145	8	.	.	PUNCT
admet-1468	146	1	each	each	DET
admet-1468	146	2	compound	compound	NOUN
admet-1468	146	3	showed	show	VERB
admet-1468	146	4	plausible	plausible	ADJ
admet-1468	146	5	antimicrobial	antimicrobial	ADJ
admet-1468	146	6	activity	activity	NOUN
admet-1468	146	7	in	in	ADP
admet-1468	146	8	a	a	DET
admet-1468	146	9	dose	dose	NOUN
admet-1468	146	10	-	-	PUNCT
admet-1468	146	11	dependent	dependent	ADJ
admet-1468	146	12	way	way	NOUN
admet-1468	146	13	.	.	PUNCT
admet-1468	147	1	among	among	ADP
admet-1468	147	2	the	the	DET
admet-1468	147	3	synthesized	synthesize	VERB
admet-1468	147	4	derivatives	derivative	NOUN
admet-1468	147	5	,	,	PUNCT
admet-1468	147	6	dtbsb	dtbsb	NOUN
admet-1468	147	7	was	be	AUX
admet-1468	147	8	most	most	ADV
admet-1468	147	9	active	active	ADJ
admet-1468	147	10	against	against	ADP
admet-1468	147	11	staphylococcus	staphylococcus	NOUN
admet-1468	147	12	aureus	aureus	NOUN
admet-1468	147	13	,	,	PUNCT
admet-1468	147	14	followed	follow	VERB
admet-1468	147	15	by	by	ADP
admet-1468	147	16	dtbsn	dtbsn	NOUN
admet-1468	147	17	,	,	PUNCT
admet-1468	147	18	dtbsa	dtbsa	NOUN
admet-1468	147	19	and	and	CCONJ
admet-1468	147	20	dtbsc	dtbsc	NOUN
admet-1468	147	21	.	.	PUNCT
admet-1468	148	1	dtbsb	dtbsb	PROPN
admet-1468	148	2	was	be	AUX
admet-1468	148	3	most	most	ADV
admet-1468	148	4	active	active	ADJ
admet-1468	148	5	against	against	ADP
admet-1468	148	6	gram	gram	NOUN
admet-1468	148	7	-	-	PUNCT
admet-1468	148	8	negative	negative	ADJ
admet-1468	148	9	organism	organism	NOUN
admet-1468	148	10	pseudomonas	pseudomona	NOUN
admet-1468	148	11	aeruginosa	aeruginosa	PROPN
admet-1468	148	12	admet	admet	PROPN
admet-1468	148	13	&	&	CCONJ
admet-1468	148	14	dmpk	dmpk	PROPN
admet-1468	148	15	11(1	11(1	NUM
admet-1468	148	16	)	)	PUNCT
admet-1468	148	17	(	(	PUNCT
admet-1468	148	18	2023	2023	NUM
admet-1468	148	19	)	)	PUNCT
admet-1468	148	20	81	81	NUM
admet-1468	148	21	-	-	SYM
admet-1468	148	22	96	96	NUM
admet-1468	148	23	coumarin	coumarin	NOUN
admet-1468	148	24	-	-	PUNCT
admet-1468	148	25	quinone	quinone	NOUN
admet-1468	148	26	hybrids	hybrid	NOUN
admet-1468	148	27	doi	doi	NOUN
admet-1468	148	28	:	:	PUNCT
admet-1468	148	29	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	148	30	87	87	NUM
admet-1468	148	31	by	by	ADP
admet-1468	148	32	90	90	NUM
admet-1468	148	33	%	%	NOUN
admet-1468	148	34	at	at	ADP
admet-1468	148	35	the	the	DET
admet-1468	148	36	highest	high	ADJ
admet-1468	148	37	concentration	concentration	NOUN
admet-1468	148	38	.	.	PUNCT
admet-1468	149	1	dtbsc	dtbsc	PROPN
admet-1468	149	2	was	be	AUX
admet-1468	149	3	found	find	VERB
admet-1468	149	4	to	to	PART
admet-1468	149	5	be	be	AUX
admet-1468	149	6	the	the	DET
admet-1468	149	7	least	least	ADV
admet-1468	149	8	active	active	ADJ
admet-1468	149	9	analog	analog	NOUN
admet-1468	149	10	,	,	PUNCT
admet-1468	149	11	with	with	ADP
admet-1468	149	12	about	about	ADV
admet-1468	149	13	20	20	NUM
admet-1468	149	14	%	%	NOUN
admet-1468	149	15	bacterial	bacterial	ADJ
admet-1468	149	16	growth	growth	NOUN
admet-1468	149	17	at	at	ADP
admet-1468	149	18	higher	high	ADJ
admet-1468	149	19	concentrations	concentration	NOUN
admet-1468	149	20	.	.	PUNCT
admet-1468	150	1	the	the	DET
admet-1468	150	2	screening	screening	NOUN
admet-1468	150	3	data	datum	NOUN
admet-1468	150	4	indicated	indicate	VERB
admet-1468	150	5	that	that	SCONJ
admet-1468	150	6	dtbsb	dtbsb	NOUN
admet-1468	150	7	showed	show	VERB
admet-1468	150	8	significant	significant	ADJ
admet-1468	150	9	activity	activity	NOUN
admet-1468	150	10	against	against	ADP
admet-1468	150	11	candida	candida	NOUN
admet-1468	150	12	albicans	albican	NOUN
admet-1468	150	13	.	.	PUNCT
admet-1468	151	1	figure	figure	NOUN
admet-1468	151	2	2	2	NUM
admet-1468	151	3	.	.	NOUN
admet-1468	152	1	results	result	NOUN
admet-1468	152	2	of	of	ADP
admet-1468	152	3	antimicrobial	antimicrobial	ADJ
admet-1468	152	4	activity	activity	NOUN
admet-1468	152	5	ic50	ic50	PROPN
admet-1468	152	6	was	be	AUX
admet-1468	152	7	calculated	calculate	VERB
admet-1468	152	8	and	and	CCONJ
admet-1468	152	9	tabulated	tabulate	VERB
admet-1468	152	10	in	in	ADP
admet-1468	152	11	table	table	NOUN
admet-1468	152	12	1	1	NUM
admet-1468	152	13	.	.	PUNCT
admet-1468	153	1	in	in	ADP
admet-1468	153	2	terms	term	NOUN
admet-1468	153	3	of	of	ADP
admet-1468	153	4	the	the	DET
admet-1468	153	5	ic50	ic50	PROPN
admet-1468	153	6	values	value	NOUN
admet-1468	153	7	,	,	PUNCT
admet-1468	153	8	all	all	DET
admet-1468	153	9	the	the	DET
admet-1468	153	10	analogs	analog	NOUN
admet-1468	153	11	have	have	VERB
admet-1468	153	12	good	good	ADJ
admet-1468	153	13	to	to	ADP
admet-1468	153	14	moderate	moderate	ADJ
admet-1468	153	15	antimicrobial	antimicrobial	ADJ
admet-1468	153	16	activity	activity	NOUN
admet-1468	153	17	against	against	ADP
admet-1468	153	18	the	the	DET
admet-1468	153	19	three	three	NUM
admet-1468	153	20	microorganisms	microorganism	NOUN
admet-1468	153	21	.	.	PUNCT
admet-1468	154	1	the	the	DET
admet-1468	154	2	standard	standard	PROPN
admet-1468	154	3	compounds	compound	VERB
admet-1468	154	4	streptomycin	streptomycin	PROPN
admet-1468	154	5	(	(	PUNCT
admet-1468	154	6	str	str	NOUN
admet-1468	154	7	)	)	PUNCT
admet-1468	154	8	and	and	CCONJ
admet-1468	154	9	itraconazole	itraconazole	NOUN
admet-1468	154	10	(	(	PUNCT
admet-1468	154	11	itr	itr	PROPN
admet-1468	154	12	)	)	PUNCT
admet-1468	154	13	exhibited	exhibit	VERB
admet-1468	154	14	the	the	DET
admet-1468	154	15	ic50	ic50	PROPN
admet-1468	154	16	value	value	NOUN
admet-1468	154	17	of	of	ADP
admet-1468	154	18	76.96	76.96	NUM
admet-1468	154	19	±	±	NUM
admet-1468	154	20	4.46	4.46	NUM
admet-1468	154	21	μm	μm	NOUN
admet-1468	154	22	and	and	CCONJ
admet-1468	154	23	56.49	56.49	NUM
admet-1468	154	24	±	±	NUM
admet-1468	154	25	0.82	0.82	NUM
admet-1468	154	26	μm	μm	NOUN
admet-1468	154	27	,	,	PUNCT
admet-1468	154	28	respectively	respectively	ADV
admet-1468	154	29	.	.	PUNCT
admet-1468	155	1	compared	compare	VERB
admet-1468	155	2	to	to	ADP
admet-1468	155	3	str	str	PROPN
admet-1468	155	4	,	,	PUNCT
admet-1468	155	5	dtbsb	dtbsb	PROPN
admet-1468	155	6	exhibited	exhibit	VERB
admet-1468	155	7	good	good	ADJ
admet-1468	155	8	antibacterial	antibacterial	ADJ
admet-1468	155	9	activity	activity	NOUN
admet-1468	155	10	against	against	ADP
admet-1468	155	11	gram	gram	NOUN
admet-1468	155	12	-	-	PUNCT
admet-1468	155	13	positive	positive	ADJ
admet-1468	155	14	bacteria	bacteria	NOUN
admet-1468	155	15	staphylococcus	staphylococcus	NOUN
admet-1468	155	16	aureus	aureus	NOUN
admet-1468	155	17	(	(	PUNCT
admet-1468	155	18	ic50	ic50	PROPN
admet-1468	155	19	=	=	PROPN
admet-1468	155	20	107.28	107.28	NUM
admet-1468	155	21	±	±	NUM
admet-1468	155	22	1.23	1.23	NUM
admet-1468	155	23	μm	μm	NUM
admet-1468	155	24	)	)	PUNCT
admet-1468	155	25	.	.	PUNCT
admet-1468	156	1	in	in	ADP
admet-1468	156	2	terms	term	NOUN
admet-1468	156	3	of	of	ADP
admet-1468	156	4	the	the	DET
admet-1468	156	5	ic50	ic50	PROPN
admet-1468	156	6	value	value	NOUN
admet-1468	156	7	,	,	PUNCT
admet-1468	156	8	the	the	DET
admet-1468	156	9	analogs	analog	NOUN
admet-1468	156	10	dtbsb	dtbsb	NOUN
admet-1468	156	11	was	be	AUX
admet-1468	156	12	also	also	ADV
admet-1468	156	13	most	most	ADV
admet-1468	156	14	active	active	ADJ
admet-1468	156	15	against	against	ADP
admet-1468	156	16	pseudomonas	pseudomona	NOUN
admet-1468	156	17	aeruginosa	aeruginosa	NOUN
admet-1468	156	18	(	(	PUNCT
admet-1468	156	19	ic50	ic50	PROPN
admet-1468	156	20	=	=	PROPN
admet-1468	156	21	129.63	129.63	NUM
admet-1468	156	22	±	±	NUM
admet-1468	156	23	2.50	2.50	NUM
admet-1468	156	24	μm	μm	NUM
admet-1468	156	25	)	)	PUNCT
admet-1468	156	26	,	,	PUNCT
admet-1468	156	27	while	while	SCONJ
admet-1468	156	28	dtbsc	dtbsc	NOUN
admet-1468	156	29	was	be	AUX
admet-1468	156	30	the	the	DET
admet-1468	156	31	least	least	ADV
admet-1468	156	32	active	active	ADJ
admet-1468	156	33	analog	analog	NOUN
admet-1468	156	34	.	.	PUNCT
admet-1468	157	1	the	the	DET
admet-1468	157	2	ic50	ic50	PROPN
admet-1468	157	3	value	value	NOUN
admet-1468	157	4	of	of	ADP
admet-1468	157	5	dtbsb	dtbsb	NOUN
admet-1468	157	6	was	be	AUX
admet-1468	157	7	close	close	ADJ
admet-1468	157	8	to	to	ADP
admet-1468	157	9	the	the	DET
admet-1468	157	10	ic50	ic50	PROPN
admet-1468	157	11	value	value	NOUN
admet-1468	157	12	of	of	ADP
admet-1468	157	13	the	the	DET
admet-1468	157	14	control	control	NOUN
admet-1468	157	15	compound	compound	NOUN
admet-1468	157	16	str	str	NOUN
admet-1468	157	17	.	.	PUNCT
admet-1468	158	1	when	when	SCONJ
admet-1468	158	2	compared	compare	VERB
admet-1468	158	3	with	with	ADP
admet-1468	158	4	str	str	PROPN
admet-1468	158	5	,	,	PUNCT
admet-1468	158	6	the	the	DET
admet-1468	158	7	synthesized	synthesize	VERB
admet-1468	158	8	analogs	analog	NOUN
admet-1468	158	9	exhibited	exhibit	VERB
admet-1468	158	10	good	good	ADJ
admet-1468	158	11	to	to	ADP
admet-1468	158	12	moderate	moderate	ADJ
admet-1468	158	13	antibacterial	antibacterial	ADJ
admet-1468	158	14	potential	potential	NOUN
admet-1468	158	15	against	against	ADP
admet-1468	158	16	gram	gram	NOUN
admet-1468	158	17	-	-	PUNCT
admet-1468	158	18	positive	positive	ADJ
admet-1468	158	19	bacteria	bacteria	NOUN
admet-1468	158	20	pseudomonas	pseudomona	VERB
admet-1468	158	21	aeruginosa	aeruginosa	NOUN
admet-1468	158	22	.	.	PUNCT
admet-1468	159	1	further	far	ADV
admet-1468	159	2	,	,	PUNCT
admet-1468	159	3	all	all	DET
admet-1468	159	4	analogs	analog	NOUN
admet-1468	159	5	possessed	possess	VERB
admet-1468	159	6	moderate	moderate	ADJ
admet-1468	159	7	antifungal	antifungal	ADJ
admet-1468	159	8	activity	activity	NOUN
admet-1468	159	9	against	against	ADP
admet-1468	159	10	candida	candida	NOUN
admet-1468	159	11	albicans	albican	NOUN
admet-1468	159	12	.	.	PUNCT
admet-1468	160	1	among	among	ADP
admet-1468	160	2	the	the	DET
admet-1468	160	3	synthesized	synthesize	VERB
admet-1468	160	4	compounds	compound	NOUN
admet-1468	160	5	,	,	PUNCT
admet-1468	160	6	the	the	DET
admet-1468	160	7	most	most	ADV
admet-1468	160	8	potent	potent	ADJ
admet-1468	160	9	analog	analog	NOUN
admet-1468	160	10	is	be	AUX
admet-1468	160	11	dtbsb	dtbsb	ADJ
admet-1468	160	12	and	and	CCONJ
admet-1468	160	13	exhibited	exhibit	VERB
admet-1468	160	14	an	an	DET
admet-1468	160	15	ic50	ic50	PROPN
admet-1468	160	16	value	value	NOUN
admet-1468	160	17	of	of	ADP
admet-1468	160	18	121.04	121.04	NUM
admet-1468	160	19	±	±	NUM
admet-1468	160	20	1.10	1.10	NUM
admet-1468	160	21	μm	μm	NOUN
admet-1468	160	22	.	.	PUNCT
admet-1468	161	1	the	the	DET
admet-1468	161	2	ic50	ic50	PROPN
admet-1468	161	3	value	value	NOUN
admet-1468	161	4	of	of	ADP
admet-1468	161	5	standard	standard	ADJ
admet-1468	161	6	itr	itr	NOUN
admet-1468	161	7	was	be	AUX
admet-1468	161	8	56.49	56.49	NUM
admet-1468	161	9	±	±	NUM
admet-1468	161	10	0.82	0.82	NUM
admet-1468	161	11	μm	μm	NOUN
admet-1468	161	12	.	.	PUNCT
admet-1468	162	1	the	the	DET
admet-1468	162	2	other	other	ADJ
admet-1468	162	3	derivative	derivative	NOUN
admet-1468	162	4	expressed	express	VERB
admet-1468	162	5	higher	high	ADJ
admet-1468	162	6	ic50	ic50	PROPN
admet-1468	162	7	values	value	NOUN
admet-1468	162	8	,	,	PUNCT
admet-1468	162	9	which	which	PRON
admet-1468	162	10	makes	make	VERB
admet-1468	162	11	them	they	PRON
admet-1468	162	12	less	less	ADV
admet-1468	162	13	susceptible	susceptible	ADJ
admet-1468	162	14	to	to	ADP
admet-1468	162	15	candida	candida	NOUN
admet-1468	162	16	albicans	albican	NOUN
admet-1468	162	17	.	.	PUNCT
admet-1468	163	1	when	when	SCONJ
admet-1468	163	2	compared	compare	VERB
admet-1468	163	3	with	with	ADP
admet-1468	163	4	itr	itr	NOUN
admet-1468	163	5	,	,	PUNCT
admet-1468	163	6	the	the	DET
admet-1468	163	7	new	new	ADJ
admet-1468	163	8	analogs	analog	NOUN
admet-1468	163	9	have	have	VERB
admet-1468	163	10	moderate	moderate	ADJ
admet-1468	163	11	antifungal	antifungal	ADJ
admet-1468	163	12	potential	potential	NOUN
admet-1468	163	13	.	.	PUNCT
admet-1468	164	1	table	table	NOUN
admet-1468	164	2	1	1	NUM
admet-1468	164	3	.	.	PUNCT
admet-1468	165	1	ic50	ic50	PROPN
admet-1468	165	2	concentration	concentration	NOUN
admet-1468	165	3	values	value	NOUN
admet-1468	165	4	of	of	ADP
admet-1468	165	5	coumarin	coumarin	NOUN
admet-1468	165	6	-	-	PUNCT
admet-1468	165	7	quinone	quinone	NOUN
admet-1468	165	8	hybrids	hybrid	NOUN
admet-1468	165	9	microorganism	microorganism	NOUN
admet-1468	165	10	staphylococcus	staphylococcus	NOUN
admet-1468	165	11	aureus	aureus	PROPN
admet-1468	165	12	pseudomonas	pseudomona	VERB
admet-1468	165	13	aeruginosa	aeruginosa	PROPN
admet-1468	165	14	candida	candida	NOUN
admet-1468	165	15	albicans	albican	NOUN
admet-1468	165	16	compound	compound	VERB
admet-1468	165	17	ic50	ic50	PROPN
admet-1468	165	18	drug	drug	NOUN
admet-1468	165	19	concentrations	concentration	NOUN
admet-1468	165	20	(	(	PUNCT
admet-1468	165	21	µm	µm	NOUN
admet-1468	165	22	)	)	PUNCT
admet-1468	165	23	dtbsa	dtbsa	VERB
admet-1468	165	24	236.42	236.42	NUM
admet-1468	165	25	±	±	NUM
admet-1468	165	26	2.90	2.90	NUM
admet-1468	165	27	225.26	225.26	NUM
admet-1468	165	28	±	±	NUM
admet-1468	165	29	3.08	3.08	NUM
admet-1468	165	30	260.19	260.19	NUM
admet-1468	165	31	±	±	NUM
admet-1468	165	32	0.78	0.78	NUM
admet-1468	165	33	dtbsc	dtbsc	NOUN
admet-1468	165	34	250.04	250.04	NUM
admet-1468	165	35	±	±	NUM
admet-1468	165	36	3.37	3.37	NUM
admet-1468	165	37	275.70	275.70	NUM
admet-1468	165	38	±	±	NUM
admet-1468	165	39	0.77	0.77	NUM
admet-1468	165	40	246.19	246.19	NUM
admet-1468	165	41	±	±	NUM
admet-1468	165	42	8.18	8.18	NUM
admet-1468	165	43	dtbsb	dtbsb	NOUN
admet-1468	165	44	107.28	107.28	NUM
admet-1468	165	45	±	±	NUM
admet-1468	165	46	1.23	1.23	NUM
admet-1468	165	47	129.63	129.63	NUM
admet-1468	165	48	±	±	NUM
admet-1468	165	49	2.50	2.50	NUM
admet-1468	165	50	121.04	121.04	NUM
admet-1468	165	51	±	±	NUM
admet-1468	165	52	1.10	1.10	NUM
admet-1468	165	53	dtbsn	dtbsn	NOUN
admet-1468	165	54	134.67	134.67	NUM
admet-1468	165	55	±	±	NUM
admet-1468	165	56	2.94	2.94	NUM
admet-1468	165	57	172.59	172.59	NUM
admet-1468	165	58	±	±	NUM
admet-1468	165	59	2.08	2.08	NUM
admet-1468	165	60	163.75	163.75	NUM
admet-1468	165	61	±	±	NUM
admet-1468	165	62	2.58	2.58	NUM
admet-1468	165	63	str	str	NOUN
admet-1468	165	64	76.96	76.96	NUM
admet-1468	165	65	±	±	NUM
admet-1468	165	66	4.46	4.46	NUM
admet-1468	165	67	93.14	93.14	NUM
admet-1468	165	68	±	±	NUM
admet-1468	165	69	7.64	7.64	NUM
admet-1468	165	70	-	-	PUNCT
admet-1468	165	71	itr	itr	PROPN
admet-1468	165	72	--56.49	--56.49	PUNCT
admet-1468	165	73	±	±	PROPN
admet-1468	165	74	0.82	0.82	NUM
admet-1468	165	75	the	the	DET
admet-1468	165	76	most	most	ADV
admet-1468	165	77	active	active	ADJ
admet-1468	165	78	derivative	derivative	ADJ
admet-1468	165	79	,	,	PUNCT
admet-1468	165	80	dtbsb	dtbsb	NOUN
admet-1468	165	81	,	,	PUNCT
admet-1468	165	82	can	can	AUX
admet-1468	165	83	be	be	AUX
admet-1468	165	84	selected	select	VERB
admet-1468	165	85	for	for	ADP
admet-1468	165	86	further	further	ADJ
admet-1468	165	87	development	development	NOUN
admet-1468	165	88	and	and	CCONJ
admet-1468	165	89	optimization	optimization	NOUN
admet-1468	165	90	as	as	SCONJ
admet-1468	165	91	an	an	DET
admet-1468	165	92	antimicrobial	antimicrobial	ADJ
admet-1468	165	93	agent	agent	NOUN
admet-1468	165	94	can	can	AUX
admet-1468	165	95	be	be	AUX
admet-1468	165	96	selected	select	VERB
admet-1468	165	97	for	for	ADP
admet-1468	165	98	further	further	ADJ
admet-1468	165	99	development	development	NOUN
admet-1468	165	100	and	and	CCONJ
admet-1468	165	101	optimization	optimization	NOUN
admet-1468	165	102	as	as	ADP
admet-1468	165	103	an	an	DET
admet-1468	165	104	antimicrobial	antimicrobial	ADJ
admet-1468	165	105	agent	agent	NOUN
admet-1468	165	106	.	.	PUNCT
admet-1468	166	1	antioxidant	antioxidant	ADJ
admet-1468	166	2	activity	activity	NOUN
admet-1468	166	3	all	all	DET
admet-1468	166	4	coumarin	coumarin	NOUN
admet-1468	166	5	-	-	PUNCT
admet-1468	166	6	quinone	quinone	NOUN
admet-1468	166	7	hybrids	hybrid	NOUN
admet-1468	166	8	were	be	AUX
admet-1468	166	9	evaluated	evaluate	VERB
admet-1468	166	10	for	for	ADP
admet-1468	166	11	their	their	PRON
admet-1468	166	12	antioxidant	antioxidant	ADJ
admet-1468	166	13	activity	activity	NOUN
admet-1468	166	14	using	use	VERB
admet-1468	166	15	the	the	DET
admet-1468	166	16	dpph	dpph	PROPN
admet-1468	166	17	assay	assay	VERB
admet-1468	166	18	.	.	PUNCT
admet-1468	167	1	the	the	DET
admet-1468	167	2	obtained	obtain	VERB
admet-1468	167	3	results	result	NOUN
admet-1468	167	4	after	after	SCONJ
admet-1468	167	5	drug	drug	NOUN
admet-1468	167	6	treatment	treatment	NOUN
admet-1468	167	7	are	be	AUX
admet-1468	167	8	depicted	depict	VERB
admet-1468	167	9	in	in	ADP
admet-1468	167	10	figure	figure	NOUN
admet-1468	167	11	3	3	NUM
admet-1468	167	12	.	.	PUNCT
admet-1468	168	1	the	the	DET
admet-1468	168	2	scavenging	scavenge	VERB
admet-1468	168	3	activity	activity	NOUN
admet-1468	168	4	(	(	PUNCT
admet-1468	168	5	in	in	ADP
admet-1468	168	6	%	%	NOUN
admet-1468	168	7	)	)	PUNCT
admet-1468	168	8	versus	versus	ADP
admet-1468	168	9	the	the	DET
admet-1468	168	10	concentration	concentration	NOUN
admet-1468	168	11	of	of	ADP
admet-1468	168	12	test	test	NOUN
admet-1468	168	13	compounds	compound	NOUN
admet-1468	168	14	was	be	AUX
admet-1468	168	15	plotted	plot	VERB
admet-1468	168	16	and	and	CCONJ
admet-1468	168	17	presented	present	VERB
admet-1468	168	18	in	in	ADP
admet-1468	168	19	figure	figure	NOUN
admet-1468	168	20	3	3	NUM
admet-1468	168	21	.	.	PUNCT
admet-1468	169	1	the	the	DET
admet-1468	169	2	ic50	ic50	PROPN
admet-1468	169	3	concentration	concentration	NOUN
admet-1468	169	4	values	value	NOUN
admet-1468	169	5	were	be	AUX
admet-1468	169	6	determined	determine	VERB
admet-1468	169	7	from	from	ADP
admet-1468	169	8	an	an	DET
admet-1468	169	9	online	online	ADJ
admet-1468	169	10	source	source	NOUN
admet-1468	169	11	(	(	PUNCT
admet-1468	169	12	http://www.ic50.tk	http://www.ic50.tk	NUM
admet-1468	169	13	)	)	PUNCT
admet-1468	169	14	.	.	PUNCT
admet-1468	170	1	the	the	DET
admet-1468	170	2	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	170	3	http://www.ic50.tk/	http://www.ic50.tk/	PROPN
admet-1468	170	4	a.	a.	NOUN
admet-1468	170	5	pangal	pangal	PROPN
admet-1468	170	6	and	and	CCONJ
admet-1468	170	7	k.	k.	PROPN
admet-1468	170	8	ahmed	ahmed	PROPN
admet-1468	170	9	admet	admet	PROPN
admet-1468	170	10	&	&	CCONJ
admet-1468	170	11	dmpk	dmpk	PROPN
admet-1468	170	12	11(1	11(1	NUM
admet-1468	170	13	)	)	PUNCT
admet-1468	170	14	(	(	PUNCT
admet-1468	170	15	2023	2023	NUM
admet-1468	170	16	)	)	PUNCT
admet-1468	170	17	81	81	NUM
admet-1468	170	18	-	-	SYM
admet-1468	170	19	96	96	NUM
admet-1468	170	20	88	88	NUM
admet-1468	170	21	results	result	NOUN
admet-1468	170	22	obtained	obtain	VERB
admet-1468	170	23	were	be	AUX
admet-1468	170	24	compared	compare	VERB
admet-1468	170	25	with	with	ADP
admet-1468	170	26	the	the	DET
admet-1468	170	27	ic50	ic50	PROPN
admet-1468	170	28	value	value	NOUN
admet-1468	170	29	of	of	ADP
admet-1468	170	30	ascorbic	ascorbic	NOUN
admet-1468	170	31	acid	acid	NOUN
admet-1468	170	32	(	(	PUNCT
admet-1468	170	33	standard	standard	NOUN
admet-1468	170	34	/	/	SYM
admet-1468	170	35	std	std	PROPN
admet-1468	170	36	)	)	PUNCT
admet-1468	170	37	.	.	PUNCT
admet-1468	171	1	the	the	DET
admet-1468	171	2	results	result	NOUN
admet-1468	171	3	revealed	reveal	VERB
admet-1468	171	4	that	that	SCONJ
admet-1468	171	5	dtbsb	dtbsb	NOUN
admet-1468	171	6	and	and	CCONJ
admet-1468	171	7	dtbsn	dtbsn	NOUN
admet-1468	171	8	were	be	AUX
admet-1468	171	9	highly	highly	ADV
admet-1468	171	10	active	active	ADJ
admet-1468	171	11	.	.	PUNCT
admet-1468	172	1	the	the	DET
admet-1468	172	2	other	other	ADJ
admet-1468	172	3	analogs	analog	NOUN
admet-1468	172	4	showed	show	VERB
admet-1468	172	5	good	good	ADJ
admet-1468	172	6	antioxidant	antioxidant	ADJ
admet-1468	172	7	activity	activity	NOUN
admet-1468	172	8	when	when	SCONJ
admet-1468	172	9	compared	compare	VERB
admet-1468	172	10	with	with	ADP
admet-1468	172	11	the	the	DET
admet-1468	172	12	standard	standard	NOUN
admet-1468	172	13	.	.	PUNCT
admet-1468	173	1	the	the	DET
admet-1468	173	2	scavenging	scavenge	VERB
admet-1468	173	3	effect	effect	NOUN
admet-1468	173	4	of	of	ADP
admet-1468	173	5	the	the	DET
admet-1468	173	6	test	test	NOUN
admet-1468	173	7	compounds	compound	NOUN
admet-1468	173	8	increased	increase	VERB
admet-1468	173	9	in	in	ADP
admet-1468	173	10	a	a	DET
admet-1468	173	11	dose	dose	NOUN
admet-1468	173	12	-	-	PUNCT
admet-1468	173	13	dependent	dependent	ADJ
admet-1468	173	14	manner	manner	NOUN
admet-1468	173	15	.	.	PUNCT
admet-1468	174	1	the	the	DET
admet-1468	174	2	ic50	ic50	PROPN
admet-1468	174	3	values	value	NOUN
admet-1468	174	4	for	for	ADP
admet-1468	174	5	the	the	DET
admet-1468	174	6	hybrids	hybrid	NOUN
admet-1468	174	7	were	be	AUX
admet-1468	174	8	10.82	10.82	NUM
admet-1468	174	9	,	,	PUNCT
admet-1468	174	10	19.20	19.20	NUM
admet-1468	174	11	,	,	PUNCT
admet-1468	174	12	18.71	18.71	NUM
admet-1468	174	13	,	,	PUNCT
admet-1468	174	14	11.63	11.63	NUM
admet-1468	174	15	and	and	CCONJ
admet-1468	174	16	13.90	13.90	NUM
admet-1468	174	17	μg	μg	PROPN
admet-1468	174	18	/	/	SYM
admet-1468	174	19	ml	ml	PROPN
admet-1468	174	20	,	,	PUNCT
admet-1468	174	21	respectively	respectively	ADV
admet-1468	174	22	,	,	PUNCT
admet-1468	174	23	which	which	PRON
admet-1468	174	24	were	be	AUX
admet-1468	174	25	comparable	comparable	ADJ
admet-1468	174	26	to	to	ADP
admet-1468	174	27	the	the	DET
admet-1468	174	28	ic50	ic50	PROPN
admet-1468	174	29	value	value	NOUN
admet-1468	174	30	of	of	ADP
admet-1468	174	31	ascorbic	ascorbic	NOUN
admet-1468	174	32	acid	acid	NOUN
admet-1468	174	33	.	.	PUNCT
admet-1468	175	1	among	among	ADP
admet-1468	175	2	the	the	DET
admet-1468	175	3	new	new	ADJ
admet-1468	175	4	hybrid	hybrid	ADJ
admet-1468	175	5	compounds	compound	NOUN
admet-1468	175	6	,	,	PUNCT
admet-1468	175	7	dtbsn	dtbsn	NOUN
admet-1468	175	8	exhibited	exhibit	VERB
admet-1468	175	9	the	the	DET
admet-1468	175	10	best	good	ADJ
admet-1468	175	11	antioxidant	antioxidant	ADJ
admet-1468	175	12	activity	activity	NOUN
admet-1468	175	13	.	.	PUNCT
admet-1468	176	1	figure	figure	NOUN
admet-1468	176	2	3	3	NUM
admet-1468	176	3	.	.	NOUN
admet-1468	176	4	results	result	NOUN
admet-1468	176	5	of	of	ADP
admet-1468	176	6	antioxidant	antioxidant	ADJ
admet-1468	176	7	activity	activity	NOUN
admet-1468	176	8	(	(	PUNCT
admet-1468	176	9	1	1	NUM
admet-1468	176	10	=	=	NOUN
admet-1468	176	11	std	std	NOUN
admet-1468	176	12	,	,	PUNCT
admet-1468	176	13	2	2	NUM
admet-1468	176	14	=	=	NOUN
admet-1468	176	15	dtbsa	dtbsa	NOUN
admet-1468	176	16	,	,	PUNCT
admet-1468	176	17	3	3	NUM
admet-1468	176	18	=	=	SYM
admet-1468	176	19	dtbsc	dtbsc	NOUN
admet-1468	176	20	,	,	PUNCT
admet-1468	176	21	4	4	NUM
admet-1468	176	22	=	=	SYM
admet-1468	176	23	dtbsb	dtbsb	NOUN
admet-1468	176	24	,	,	PUNCT
admet-1468	176	25	5	5	NUM
admet-1468	176	26	=	=	NUM
admet-1468	176	27	dtbsn	dtbsn	NOUN
admet-1468	176	28	)	)	PUNCT
admet-1468	176	29	anticancer	anticancer	NOUN
admet-1468	176	30	studies	study	NOUN
admet-1468	176	31	all	all	DET
admet-1468	176	32	coumarin	coumarin	NOUN
admet-1468	176	33	-	-	PUNCT
admet-1468	176	34	quinone	quinone	NOUN
admet-1468	176	35	hybrids	hybrid	NOUN
admet-1468	176	36	were	be	AUX
admet-1468	176	37	evaluated	evaluate	VERB
admet-1468	176	38	for	for	ADP
admet-1468	176	39	their	their	PRON
admet-1468	176	40	in	in	X
admet-1468	176	41	vitro	vitro	X
admet-1468	176	42	antiproliferative	antiproliferative	ADJ
admet-1468	176	43	activity	activity	NOUN
admet-1468	176	44	against	against	ADP
admet-1468	176	45	a	a	DET
admet-1468	176	46	set	set	NOUN
admet-1468	176	47	of	of	ADP
admet-1468	176	48	human	human	ADJ
admet-1468	176	49	cancer	cancer	NOUN
admet-1468	176	50	cell	cell	NOUN
admet-1468	176	51	lines	line	NOUN
admet-1468	176	52	,	,	PUNCT
admet-1468	176	53	which	which	PRON
admet-1468	176	54	includes	include	VERB
admet-1468	176	55	two	two	NUM
admet-1468	176	56	breast	breast	NOUN
admet-1468	176	57	cancer	cancer	NOUN
admet-1468	176	58	cell	cell	NOUN
admet-1468	176	59	lines	line	NOUN
admet-1468	176	60	(	(	PUNCT
admet-1468	176	61	mcf-7	mcf-7	X
admet-1468	176	62	and	and	CCONJ
admet-1468	176	63	mda	mda	PROPN
admet-1468	176	64	-	-	PUNCT
admet-1468	176	65	mb-231	mb-231	PROPN
admet-1468	176	66	)	)	PUNCT
admet-1468	176	67	,	,	PUNCT
admet-1468	176	68	two	two	NUM
admet-1468	176	69	colon	colon	NOUN
admet-1468	176	70	carcinoma	carcinoma	NOUN
admet-1468	176	71	cell	cell	NOUN
admet-1468	176	72	lines	line	NOUN
admet-1468	176	73	(	(	PUNCT
admet-1468	176	74	colo-205	colo-205	NOUN
admet-1468	176	75	and	and	CCONJ
admet-1468	176	76	ht-29	ht-29	PRON
admet-1468	176	77	)	)	PUNCT
admet-1468	176	78	and	and	CCONJ
admet-1468	176	79	one	one	NUM
admet-1468	176	80	lung	lung	NOUN
admet-1468	176	81	carcinoma	carcinoma	NOUN
admet-1468	176	82	(	(	PUNCT
admet-1468	176	83	a549	a549	PROPN
admet-1468	176	84	)	)	PUNCT
admet-1468	176	85	.	.	PUNCT
admet-1468	177	1	all	all	DET
admet-1468	177	2	experiments	experiment	NOUN
admet-1468	177	3	were	be	AUX
admet-1468	177	4	performed	perform	VERB
admet-1468	177	5	in	in	ADP
admet-1468	177	6	triplicates	triplicate	NOUN
admet-1468	177	7	and	and	CCONJ
admet-1468	177	8	the	the	DET
admet-1468	177	9	obtained	obtain	VERB
admet-1468	177	10	results	result	NOUN
admet-1468	177	11	are	be	AUX
admet-1468	177	12	expressed	express	VERB
admet-1468	177	13	as	as	SCONJ
admet-1468	177	14	the	the	DET
admet-1468	177	15	percent	percent	NOUN
admet-1468	177	16	growth	growth	NOUN
admet-1468	177	17	(	(	PUNCT
admet-1468	177	18	%	%	INTJ
admet-1468	177	19	)	)	PUNCT
admet-1468	177	20	at	at	ADP
admet-1468	177	21	different	different	ADJ
admet-1468	177	22	concentrations	concentration	NOUN
admet-1468	177	23	of	of	ADP
admet-1468	177	24	test	test	NOUN
admet-1468	177	25	compounds	compound	NOUN
admet-1468	177	26	expressed	express	VERB
admet-1468	177	27	in	in	ADP
admet-1468	177	28	μm	μm	NUM
admet-1468	177	29	.	.	NOUN
admet-1468	177	30	5	5	NUM
admet-1468	177	31	-	-	PUNCT
admet-1468	177	32	fluorouracil	fluorouracil	NOUN
admet-1468	177	33	(	(	PUNCT
admet-1468	177	34	5	5	NUM
admet-1468	177	35	-	-	PUNCT
admet-1468	177	36	fu	fu	NOUN
admet-1468	177	37	)	)	PUNCT
admet-1468	177	38	was	be	AUX
admet-1468	177	39	used	use	VERB
admet-1468	177	40	as	as	ADP
admet-1468	177	41	standard	standard	ADJ
admet-1468	177	42	.	.	PUNCT
admet-1468	178	1	drug	drug	NOUN
admet-1468	178	2	concentration	concentration	NOUN
admet-1468	178	3	causing	cause	VERB
admet-1468	178	4	50	50	NUM
admet-1468	178	5	%	%	NOUN
admet-1468	178	6	inhibition	inhibition	NOUN
admet-1468	178	7	of	of	ADP
admet-1468	178	8	cell	cell	NOUN
admet-1468	178	9	growth	growth	NOUN
admet-1468	178	10	was	be	AUX
admet-1468	178	11	characterized	characterize	VERB
admet-1468	178	12	as	as	ADP
admet-1468	178	13	ic50	ic50	PROPN
admet-1468	178	14	value	value	NOUN
admet-1468	178	15	.	.	PUNCT
admet-1468	179	1	the	the	DET
admet-1468	179	2	results	result	NOUN
admet-1468	179	3	revealed	reveal	VERB
admet-1468	179	4	that	that	SCONJ
admet-1468	179	5	all	all	DET
admet-1468	179	6	coumarin	coumarin	NOUN
admet-1468	179	7	-	-	PUNCT
admet-1468	179	8	quinone	quinone	NOUN
admet-1468	179	9	hybrid	hybrid	NOUN
admet-1468	179	10	compounds	compound	NOUN
admet-1468	179	11	exhibited	exhibit	VERB
admet-1468	179	12	considerable	considerable	ADJ
admet-1468	179	13	activity	activity	NOUN
admet-1468	179	14	against	against	ADP
admet-1468	179	15	all	all	DET
admet-1468	179	16	tested	test	VERB
admet-1468	179	17	cancer	cancer	NOUN
admet-1468	179	18	cell	cell	NOUN
admet-1468	179	19	lines	line	NOUN
admet-1468	179	20	.	.	PUNCT
admet-1468	180	1	graphs	graph	NOUN
admet-1468	180	2	of	of	ADP
admet-1468	180	3	the	the	DET
admet-1468	180	4	dosedependent	dosedependent	NOUN
admet-1468	180	5	effects	effect	NOUN
admet-1468	180	6	of	of	ADP
admet-1468	180	7	the	the	DET
admet-1468	180	8	hybrids	hybrid	NOUN
admet-1468	180	9	on	on	ADP
admet-1468	180	10	these	these	DET
admet-1468	180	11	cell	cell	NOUN
admet-1468	180	12	lines	line	NOUN
admet-1468	180	13	are	be	AUX
admet-1468	180	14	shown	show	VERB
admet-1468	180	15	in	in	ADP
admet-1468	180	16	figure	figure	NOUN
admet-1468	180	17	4	4	NUM
admet-1468	180	18	.	.	PUNCT
admet-1468	180	19	figure	figure	VERB
admet-1468	180	20	4	4	NUM
admet-1468	180	21	.	.	PUNCT
admet-1468	180	22	effect	effect	NOUN
admet-1468	180	23	of	of	ADP
admet-1468	180	24	coumarin	coumarin	NOUN
admet-1468	180	25	-	-	PUNCT
admet-1468	180	26	quinone	quinone	NOUN
admet-1468	180	27	hybrids	hybrid	NOUN
admet-1468	180	28	concentration	concentration	NOUN
admet-1468	180	29	on	on	ADP
admet-1468	180	30	cancer	cancer	NOUN
admet-1468	180	31	cell	cell	NOUN
admet-1468	180	32	growth	growth	NOUN
admet-1468	180	33	at	at	ADP
admet-1468	180	34	the	the	DET
admet-1468	180	35	indicated	indicate	VERB
admet-1468	180	36	doses	dose	NOUN
admet-1468	180	37	,	,	PUNCT
admet-1468	180	38	µm	µm	X
admet-1468	180	39	admet	admet	PROPN
admet-1468	180	40	&	&	CCONJ
admet-1468	180	41	dmpk	dmpk	PROPN
admet-1468	180	42	11(1	11(1	NUM
admet-1468	180	43	)	)	PUNCT
admet-1468	180	44	(	(	PUNCT
admet-1468	180	45	2023	2023	NUM
admet-1468	180	46	)	)	PUNCT
admet-1468	180	47	81	81	NUM
admet-1468	180	48	-	-	SYM
admet-1468	180	49	96	96	NUM
admet-1468	180	50	coumarin	coumarin	NOUN
admet-1468	180	51	-	-	PUNCT
admet-1468	180	52	quinone	quinone	NOUN
admet-1468	180	53	hybrids	hybrid	NOUN
admet-1468	180	54	doi	doi	NOUN
admet-1468	180	55	:	:	PUNCT
admet-1468	180	56	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	180	57	89	89	NUM
admet-1468	180	58	from	from	ADP
admet-1468	180	59	the	the	DET
admet-1468	180	60	antiproliferative	antiproliferative	NOUN
admet-1468	180	61	screening	screen	VERB
admet-1468	180	62	data	datum	NOUN
admet-1468	180	63	,	,	PUNCT
admet-1468	180	64	it	it	PRON
admet-1468	180	65	is	be	AUX
admet-1468	180	66	apparent	apparent	ADJ
admet-1468	180	67	that	that	SCONJ
admet-1468	180	68	with	with	ADP
admet-1468	180	69	an	an	DET
admet-1468	180	70	increase	increase	NOUN
admet-1468	180	71	in	in	ADP
admet-1468	180	72	the	the	DET
admet-1468	180	73	concentrations	concentration	NOUN
admet-1468	180	74	of	of	ADP
admet-1468	180	75	the	the	DET
admet-1468	180	76	tested	test	VERB
admet-1468	180	77	compounds	compound	NOUN
admet-1468	180	78	,	,	PUNCT
admet-1468	180	79	the	the	DET
admet-1468	180	80	antiproliferative	antiproliferative	ADJ
admet-1468	180	81	potential	potential	NOUN
admet-1468	180	82	of	of	ADP
admet-1468	180	83	the	the	DET
admet-1468	180	84	hybrids	hybrid	NOUN
admet-1468	180	85	increases	increase	NOUN
admet-1468	180	86	,	,	PUNCT
admet-1468	180	87	too	too	ADV
admet-1468	180	88	.	.	PUNCT
admet-1468	181	1	the	the	DET
admet-1468	181	2	ic50	ic50	PROPN
admet-1468	181	3	values	value	NOUN
admet-1468	181	4	were	be	AUX
admet-1468	181	5	calculated	calculate	VERB
admet-1468	181	6	using	use	VERB
admet-1468	181	7	the	the	DET
admet-1468	181	8	graph	graph	NOUN
admet-1468	181	9	in	in	ADP
admet-1468	181	10	figure	figure	NOUN
admet-1468	181	11	4	4	NUM
admet-1468	181	12	.	.	PUNCT
admet-1468	182	1	the	the	DET
admet-1468	182	2	results	result	NOUN
admet-1468	182	3	are	be	AUX
admet-1468	182	4	shown	show	VERB
admet-1468	182	5	in	in	ADP
admet-1468	182	6	table	table	NOUN
admet-1468	182	7	2	2	NUM
admet-1468	182	8	.	.	PUNCT
admet-1468	183	1	the	the	DET
admet-1468	183	2	hybrids	hybrid	NOUN
admet-1468	183	3	dtbsb	dtbsb	VERB
admet-1468	183	4	and	and	CCONJ
admet-1468	183	5	dtbsn	dtbsn	NOUN
admet-1468	183	6	exhibited	exhibit	VERB
admet-1468	183	7	good	good	ADJ
admet-1468	183	8	antiproliferative	antiproliferative	ADJ
admet-1468	183	9	activity	activity	NOUN
admet-1468	183	10	against	against	ADP
admet-1468	183	11	all	all	DET
admet-1468	183	12	cancer	cancer	NOUN
admet-1468	183	13	cell	cell	NOUN
admet-1468	183	14	lines	line	NOUN
admet-1468	183	15	.	.	PUNCT
admet-1468	184	1	dtbsb	dtbsb	PROPN
admet-1468	184	2	was	be	AUX
admet-1468	184	3	more	more	ADV
admet-1468	184	4	active	active	ADJ
admet-1468	184	5	against	against	ADP
admet-1468	184	6	mcf-7	mcf-7	PUNCT
admet-1468	184	7	and	and	CCONJ
admet-1468	184	8	ht-29	ht-29	PUNCT
admet-1468	184	9	cell	cell	NOUN
admet-1468	184	10	lines	line	NOUN
admet-1468	184	11	showing	show	VERB
admet-1468	184	12	remarkable	remarkable	ADJ
admet-1468	184	13	ic50	ic50	PROPN
admet-1468	184	14	values	value	NOUN
admet-1468	184	15	.	.	PUNCT
admet-1468	185	1	however	however	ADV
admet-1468	185	2	,	,	PUNCT
admet-1468	185	3	dtbsn	dtbsn	NOUN
admet-1468	185	4	exhibited	exhibit	VERB
admet-1468	185	5	its	its	PRON
admet-1468	185	6	highest	high	ADJ
admet-1468	185	7	potential	potential	NOUN
admet-1468	185	8	against	against	ADP
admet-1468	185	9	mda	mda	PROPN
admet-1468	185	10	-	-	PUNCT
admet-1468	185	11	mb-231	mb-231	PROPN
admet-1468	185	12	,	,	PUNCT
admet-1468	185	13	colo-205	colo-205	NOUN
admet-1468	185	14	and	and	CCONJ
admet-1468	185	15	a-549	a-549	NOUN
admet-1468	185	16	cancer	cancer	NOUN
admet-1468	185	17	cells	cell	NOUN
admet-1468	185	18	.	.	PUNCT
admet-1468	186	1	the	the	DET
admet-1468	186	2	ic50	ic50	PROPN
admet-1468	186	3	values	value	NOUN
admet-1468	186	4	of	of	ADP
admet-1468	186	5	both	both	DET
admet-1468	186	6	analogs	analog	NOUN
admet-1468	186	7	were	be	AUX
admet-1468	186	8	in	in	ADP
admet-1468	186	9	the	the	DET
admet-1468	186	10	range	range	NOUN
admet-1468	186	11	of	of	ADP
admet-1468	186	12	50	50	NUM
admet-1468	186	13	to	to	PART
admet-1468	186	14	100	100	NUM
admet-1468	186	15	µm	µm	ADP
admet-1468	186	16	making	make	VERB
admet-1468	186	17	these	these	DET
admet-1468	186	18	compounds	compound	NOUN
admet-1468	186	19	relevant	relevant	ADJ
admet-1468	186	20	for	for	ADP
admet-1468	186	21	further	further	ADJ
admet-1468	186	22	lead	lead	NOUN
admet-1468	186	23	development	development	NOUN
admet-1468	186	24	.	.	PUNCT
admet-1468	187	1	some	some	PRON
admet-1468	187	2	of	of	ADP
admet-1468	187	3	the	the	DET
admet-1468	187	4	ic50	ic50	PROPN
admet-1468	187	5	values	value	NOUN
admet-1468	187	6	of	of	ADP
admet-1468	187	7	dtbsb	dtbsb	NOUN
admet-1468	187	8	and	and	CCONJ
admet-1468	187	9	dtbsn	dtbsn	NOUN
admet-1468	187	10	were	be	AUX
admet-1468	187	11	comparable	comparable	ADJ
admet-1468	187	12	with	with	ADP
admet-1468	187	13	the	the	DET
admet-1468	187	14	ic50	ic50	PROPN
admet-1468	187	15	value	value	NOUN
admet-1468	187	16	of	of	ADP
admet-1468	187	17	standard	standard	ADJ
admet-1468	187	18	5	5	NUM
admet-1468	187	19	-	-	PUNCT
admet-1468	187	20	fu	fu	NOUN
admet-1468	187	21	.	.	PUNCT
admet-1468	188	1	all	all	DET
admet-1468	188	2	the	the	DET
admet-1468	188	3	derivatives	derivative	NOUN
admet-1468	188	4	are	be	AUX
admet-1468	188	5	active	active	ADJ
admet-1468	188	6	against	against	ADP
admet-1468	188	7	all	all	DET
admet-1468	188	8	tested	test	VERB
admet-1468	188	9	cancer	cancer	NOUN
admet-1468	188	10	cell	cell	NOUN
admet-1468	188	11	lines	line	NOUN
admet-1468	188	12	.	.	PUNCT
admet-1468	189	1	table	table	NOUN
admet-1468	189	2	2	2	NUM
admet-1468	189	3	.	.	NUM
admet-1468	189	4	calculated	calculate	VERB
admet-1468	189	5	ic50	ic50	PROPN
admet-1468	189	6	values	value	NOUN
admet-1468	189	7	(	(	PUNCT
admet-1468	189	8	µm	µm	NOUN
admet-1468	189	9	)	)	PUNCT
admet-1468	189	10	and	and	CCONJ
admet-1468	189	11	selectivity	selectivity	NOUN
admet-1468	189	12	index	index	NOUN
admet-1468	189	13	(	(	PUNCT
admet-1468	189	14	si	si	NOUN
admet-1468	189	15	)	)	PUNCT
admet-1468	189	16	of	of	ADP
admet-1468	189	17	coumarin	coumarin	NOUN
admet-1468	189	18	-	-	PUNCT
admet-1468	189	19	quinone	quinone	NOUN
admet-1468	189	20	hybrids	hybrid	NOUN
admet-1468	189	21	cell	cell	NOUN
admet-1468	189	22	lines	line	NOUN
admet-1468	189	23	mcf-7	mcf-7	PUNCT
admet-1468	189	24	mda	mda	PROPN
admet-1468	189	25	-	-	PUNCT
admet-1468	189	26	mb-231	mb-231	PROPN
admet-1468	189	27	colo-205	colo-205	NOUN
admet-1468	189	28	ht-29	ht-29	PUNCT
admet-1468	190	1	a-549	a-549	PROPN
admet-1468	190	2	pbmc	pbmc	NOUN
admet-1468	190	3	compounds	compound	VERB
admet-1468	190	4	ic50	ic50	PROPN
admet-1468	190	5	drug	drug	NOUN
admet-1468	190	6	concentrations	concentration	NOUN
admet-1468	190	7	dtbsa	dtbsa	VERB
admet-1468	190	8	120.5	120.5	NUM
admet-1468	190	9	±	±	NUM
admet-1468	190	10	2.54	2.54	NUM
admet-1468	190	11	69.18	69.18	NUM
admet-1468	190	12	±	±	NUM
admet-1468	190	13	6.45	6.45	NUM
admet-1468	190	14	109.99	109.99	NUM
admet-1468	190	15	±	±	NUM
admet-1468	190	16	2.93	2.93	NUM
admet-1468	190	17	112.33	112.33	NUM
admet-1468	190	18	±	±	NUM
admet-1468	190	19	1.58	1.58	NUM
admet-1468	190	20	103.30	103.30	NUM
admet-1468	190	21	±	±	NUM
admet-1468	190	22	0.17	0.17	NUM
admet-1468	190	23	429.85	429.85	NUM
admet-1468	190	24	±	±	NUM
admet-1468	190	25	3.63	3.63	NUM
admet-1468	190	26	dtbsc	dtbsc	NOUN
admet-1468	190	27	107.88	107.88	NUM
admet-1468	190	28	±	±	NUM
admet-1468	190	29	2.47	2.47	NUM
admet-1468	190	30	58.81	58.81	NUM
admet-1468	190	31	±	±	NUM
admet-1468	190	32	7.38	7.38	NUM
admet-1468	190	33	108.93	108.93	NUM
admet-1468	190	34	±	±	NUM
admet-1468	190	35	0.76	0.76	NUM
admet-1468	190	36	107.02	107.02	NUM
admet-1468	190	37	±	±	NUM
admet-1468	190	38	2.43	2.43	NUM
admet-1468	190	39	88.50	88.50	NUM
admet-1468	190	40	±	±	NUM
admet-1468	190	41	2.01	2.01	NUM
admet-1468	190	42	423.97	423.97	NUM
admet-1468	190	43	±	±	NUM
admet-1468	190	44	2.06	2.06	NUM
admet-1468	190	45	dtbsb	dtbsb	NOUN
admet-1468	190	46	63.93	63.93	NUM
admet-1468	190	47	±	±	NUM
admet-1468	190	48	2.61	2.61	NUM
admet-1468	190	49	50.68	50.68	NUM
admet-1468	190	50	±	±	NUM
admet-1468	190	51	4.31	4.31	NUM
admet-1468	190	52	78.18	78.18	NUM
admet-1468	190	53	±	±	NUM
admet-1468	190	54	0.45	0.45	NUM
admet-1468	190	55	71.82	71.82	NUM
admet-1468	190	56	±	±	NUM
admet-1468	190	57	3.61	3.61	NUM
admet-1468	190	58	65.62	65.62	NUM
admet-1468	190	59	±	±	NUM
admet-1468	190	60	4.33	4.33	NUM
admet-1468	190	61	537.51	537.51	NUM
admet-1468	190	62	±	±	NUM
admet-1468	190	63	5.37	5.37	NUM
admet-1468	190	64	dtbsn	dtbsn	NOUN
admet-1468	190	65	76.84	76.84	NUM
admet-1468	190	66	±	±	NUM
admet-1468	190	67	4.17	4.17	NUM
admet-1468	190	68	53.29	53.29	NUM
admet-1468	190	69	±	±	NUM
admet-1468	190	70	2.22	2.22	NUM
admet-1468	190	71	78.19	78.19	NUM
admet-1468	190	72	±	±	NUM
admet-1468	190	73	2.81	2.81	NUM
admet-1468	190	74	100.30	100.30	NUM
admet-1468	190	75	±	±	NUM
admet-1468	190	76	1.97	1.97	NUM
admet-1468	190	77	66.12	66.12	NUM
admet-1468	190	78	±	±	NUM
admet-1468	190	79	0.04	0.04	NUM
admet-1468	190	80	492.3	492.3	NUM
admet-1468	190	81	±	±	NUM
admet-1468	190	82	4.75	4.75	NUM
admet-1468	190	83	5	5	NUM
admet-1468	190	84	-	-	PUNCT
admet-1468	190	85	fu	fu	NOUN
admet-1468	190	86	39.72	39.72	NUM
admet-1468	190	87	±	±	NUM
admet-1468	190	88	1.68	1.68	NUM
admet-1468	190	89	46.76	46.76	NUM
admet-1468	190	90	±	±	NUM
admet-1468	190	91	8.59	8.59	NUM
admet-1468	190	92	62.23	62.23	NUM
admet-1468	190	93	±	±	NUM
admet-1468	190	94	2.04	2.04	NUM
admet-1468	190	95	56.46	56.46	NUM
admet-1468	190	96	±	±	NUM
admet-1468	190	97	2.64	2.64	NUM
admet-1468	190	98	48.15	48.15	NUM
admet-1468	190	99	±	±	NUM
admet-1468	190	100	1.56	1.56	NUM
admet-1468	190	101	--	--	PUNCT
admet-1468	190	102	selectivity	selectivity	NOUN
admet-1468	190	103	index	index	NOUN
admet-1468	190	104	(	(	PUNCT
admet-1468	190	105	si	si	NOUN
admet-1468	190	106	)	)	PUNCT
admet-1468	190	107	dtbsa	dtbsa	VERB
admet-1468	190	108	3.57	3.57	NUM
admet-1468	190	109	6.21	6.21	NUM
admet-1468	190	110	3.91	3.91	NUM
admet-1468	190	111	3.83	3.83	NUM
admet-1468	190	112	4.16	4.16	NUM
admet-1468	190	113	--	--	PUNCT
admet-1468	190	114	dtbsc	dtbsc	NOUN
admet-1468	190	115	3.93	3.93	NUM
admet-1468	190	116	7.21	7.21	NUM
admet-1468	190	117	3.89	3.89	NUM
admet-1468	190	118	3.96	3.96	NUM
admet-1468	190	119	4.79	4.79	NUM
admet-1468	190	120	--	--	PUNCT
admet-1468	190	121	dtbsb	dtbsb	VERB
admet-1468	190	122	8.41	8.41	NUM
admet-1468	190	123	10.61	10.61	NUM
admet-1468	190	124	6.88	6.88	NUM
admet-1468	190	125	7.48	7.48	NUM
admet-1468	190	126	8.19	8.19	NUM
admet-1468	190	127	--	--	PUNCT
admet-1468	190	128	dtbsn	dtbsn	VERB
admet-1468	190	129	6.41	6.41	NUM
admet-1468	190	130	9.24	9.24	NUM
admet-1468	190	131	6.30	6.30	NUM
admet-1468	190	132	4.91	4.91	NUM
admet-1468	190	133	7.45	7.45	NUM
admet-1468	190	134	--	--	PUNCT
admet-1468	190	135	in	in	ADP
admet-1468	190	136	addition	addition	NOUN
admet-1468	190	137	,	,	PUNCT
admet-1468	190	138	all	all	DET
admet-1468	190	139	hybrids	hybrid	NOUN
admet-1468	190	140	were	be	AUX
admet-1468	190	141	virtually	virtually	ADV
admet-1468	190	142	non	non	ADJ
admet-1468	190	143	-	-	ADJ
admet-1468	190	144	toxic	toxic	ADJ
admet-1468	190	145	to	to	ADP
admet-1468	190	146	human	human	ADJ
admet-1468	190	147	normal	normal	ADJ
admet-1468	190	148	peripheral	peripheral	ADJ
admet-1468	190	149	blood	blood	NOUN
admet-1468	190	150	mononuclear	mononuclear	ADJ
admet-1468	190	151	cells	cell	NOUN
admet-1468	190	152	(	(	PUNCT
admet-1468	190	153	pbmcs	pbmcs	NOUN
admet-1468	190	154	)	)	PUNCT
admet-1468	190	155	,	,	PUNCT
admet-1468	190	156	indicating	indicate	VERB
admet-1468	190	157	a	a	DET
admet-1468	190	158	high	high	ADJ
admet-1468	190	159	selectivity	selectivity	NOUN
admet-1468	190	160	of	of	ADP
admet-1468	190	161	these	these	DET
admet-1468	190	162	compounds	compound	NOUN
admet-1468	190	163	for	for	ADP
admet-1468	190	164	cancer	cancer	NOUN
admet-1468	190	165	cells	cell	NOUN
admet-1468	190	166	.	.	PUNCT
admet-1468	191	1	the	the	DET
admet-1468	191	2	selectivity	selectivity	NOUN
admet-1468	191	3	index	index	NOUN
admet-1468	191	4	(	(	PUNCT
admet-1468	191	5	si	si	NOUN
admet-1468	191	6	)	)	PUNCT
admet-1468	191	7	of	of	ADP
admet-1468	191	8	each	each	DET
admet-1468	191	9	test	test	NOUN
admet-1468	191	10	compound	compound	NOUN
admet-1468	191	11	for	for	SCONJ
admet-1468	191	12	every	every	DET
admet-1468	191	13	cancer	cancer	NOUN
admet-1468	191	14	cell	cell	NOUN
admet-1468	191	15	line	line	NOUN
admet-1468	191	16	was	be	AUX
admet-1468	191	17	determined	determine	VERB
admet-1468	191	18	.	.	PUNCT
admet-1468	192	1	the	the	PRON
admet-1468	192	2	higher	high	ADJ
admet-1468	192	3	the	the	DET
admet-1468	192	4	si	si	PROPN
admet-1468	192	5	value	value	NOUN
admet-1468	192	6	,	,	PUNCT
admet-1468	192	7	the	the	DET
admet-1468	192	8	more	more	ADV
admet-1468	192	9	effective	effective	ADJ
admet-1468	192	10	and	and	CCONJ
admet-1468	192	11	safer	safe	ADJ
admet-1468	192	12	a	a	DET
admet-1468	192	13	drug	drug	NOUN
admet-1468	192	14	would	would	AUX
admet-1468	192	15	be	be	AUX
admet-1468	192	16	in	in	ADP
admet-1468	192	17	future	future	NOUN
admet-1468	192	18	in	in	ADP
admet-1468	192	19	vivo	vivo	ADJ
admet-1468	192	20	experiments	experiment	NOUN
admet-1468	192	21	.	.	PUNCT
admet-1468	193	1	the	the	DET
admet-1468	193	2	si	si	NOUN
admet-1468	193	3	of	of	ADP
admet-1468	193	4	a	a	DET
admet-1468	193	5	compound	compound	NOUN
admet-1468	193	6	is	be	AUX
admet-1468	193	7	a	a	DET
admet-1468	193	8	widely	widely	ADV
admet-1468	193	9	accepted	accept	VERB
admet-1468	193	10	parameter	parameter	NOUN
admet-1468	193	11	used	use	VERB
admet-1468	193	12	to	to	PART
admet-1468	193	13	express	express	VERB
admet-1468	193	14	a	a	DET
admet-1468	193	15	compound	compound	NOUN
admet-1468	193	16	’s	’s	NOUN
admet-1468	193	17	in	in	ADP
admet-1468	193	18	vitro	vitro	X
admet-1468	193	19	efficacy	efficacy	NOUN
admet-1468	193	20	in	in	ADP
admet-1468	193	21	the	the	DET
admet-1468	193	22	inhibition	inhibition	NOUN
admet-1468	193	23	of	of	ADP
admet-1468	193	24	virus	virus	NOUN
admet-1468	193	25	replication	replication	NOUN
admet-1468	193	26	[	[	X
admet-1468	193	27	35	35	NUM
admet-1468	193	28	]	]	PUNCT
admet-1468	193	29	.	.	PUNCT
admet-1468	194	1	here	here	ADV
admet-1468	194	2	,	,	PUNCT
admet-1468	194	3	the	the	DET
admet-1468	194	4	si	si	PROPN
admet-1468	194	5	values	value	NOUN
admet-1468	194	6	for	for	ADP
admet-1468	194	7	the	the	DET
admet-1468	194	8	hybrid	hybrid	ADJ
admet-1468	194	9	molecules	molecule	NOUN
admet-1468	194	10	were	be	AUX
admet-1468	194	11	calculated	calculate	VERB
admet-1468	194	12	from	from	ADP
admet-1468	194	13	the	the	DET
admet-1468	194	14	ratio	ratio	NOUN
admet-1468	194	15	of	of	ADP
admet-1468	194	16	their	their	PRON
admet-1468	194	17	ic50	ic50	PROPN
admet-1468	194	18	values	value	NOUN
admet-1468	194	19	in	in	ADP
admet-1468	194	20	tumor	tumor	NOUN
admet-1468	194	21	cells	cell	NOUN
admet-1468	194	22	and	and	CCONJ
admet-1468	194	23	that	that	PRON
admet-1468	194	24	of	of	ADP
admet-1468	194	25	normal	normal	ADJ
admet-1468	194	26	pbmcsl	pbmcsl	NOUN
admet-1468	194	27	(	(	PUNCT
admet-1468	194	28	table	table	NOUN
admet-1468	194	29	2	2	NUM
admet-1468	194	30	)	)	PUNCT
admet-1468	194	31	.	.	PUNCT
admet-1468	195	1	the	the	DET
admet-1468	195	2	selectivity	selectivity	NOUN
admet-1468	195	3	index	index	NOUN
admet-1468	195	4	indicates	indicate	VERB
admet-1468	195	5	the	the	DET
admet-1468	195	6	selectivity	selectivity	NOUN
admet-1468	195	7	of	of	ADP
admet-1468	195	8	a	a	DET
admet-1468	195	9	given	give	VERB
admet-1468	195	10	compound	compound	NOUN
admet-1468	195	11	between	between	ADP
admet-1468	195	12	normal	normal	ADJ
admet-1468	195	13	and	and	CCONJ
admet-1468	195	14	cancer	cancer	NOUN
admet-1468	195	15	cells	cell	NOUN
admet-1468	195	16	.	.	PUNCT
admet-1468	196	1	the	the	PRON
admet-1468	196	2	higher	high	ADJ
admet-1468	196	3	the	the	DET
admet-1468	196	4	magnitude	magnitude	NOUN
admet-1468	196	5	of	of	ADP
admet-1468	196	6	the	the	DET
admet-1468	196	7	selectivity	selectivity	NOUN
admet-1468	196	8	index	index	NOUN
admet-1468	196	9	,	,	PUNCT
admet-1468	196	10	the	the	PRON
admet-1468	196	11	greater	great	ADJ
admet-1468	196	12	its	its	PRON
admet-1468	196	13	tumor	tumor	NOUN
admet-1468	196	14	selectivity	selectivity	NOUN
admet-1468	196	15	is	be	AUX
admet-1468	196	16	[	[	X
admet-1468	196	17	36	36	NUM
admet-1468	196	18	]	]	PUNCT
admet-1468	196	19	.	.	PUNCT
admet-1468	197	1	the	the	DET
admet-1468	197	2	highest	high	ADJ
admet-1468	197	3	si	si	NOUN
admet-1468	197	4	values	value	NOUN
admet-1468	197	5	were	be	AUX
admet-1468	197	6	calculated	calculate	VERB
admet-1468	197	7	for	for	ADP
admet-1468	197	8	dtbsb	dtbsb	NOUN
admet-1468	197	9	including	include	VERB
admet-1468	197	10	mcf-7	mcf-7	NOUN
admet-1468	197	11	(	(	PUNCT
admet-1468	197	12	8.41	8.41	NUM
admet-1468	197	13	)	)	PUNCT
admet-1468	197	14	,	,	PUNCT
admet-1468	197	15	mda	mda	PROPN
admet-1468	197	16	-	-	PUNCT
admet-1468	197	17	mb-231	mb-231	PROPN
admet-1468	197	18	(	(	PUNCT
admet-1468	197	19	10.61	10.61	NUM
admet-1468	197	20	)	)	PUNCT
admet-1468	197	21	,	,	PUNCT
admet-1468	197	22	colo-205	colo-205	NOUN
admet-1468	197	23	(	(	PUNCT
admet-1468	197	24	6.88	6.88	NUM
admet-1468	197	25	)	)	PUNCT
admet-1468	197	26	,	,	PUNCT
admet-1468	197	27	ht-29	ht-29	PUNCT
admet-1468	197	28	(	(	PUNCT
admet-1468	197	29	7.48	7.48	NUM
admet-1468	197	30	)	)	PUNCT
admet-1468	197	31	and	and	CCONJ
admet-1468	197	32	a549	a549	PROPN
admet-1468	197	33	(	(	PUNCT
admet-1468	197	34	8.19	8.19	NUM
admet-1468	197	35	)	)	PUNCT
admet-1468	197	36	.	.	PUNCT
admet-1468	198	1	in	in	ADP
admet-1468	198	2	general	general	ADJ
admet-1468	198	3	,	,	PUNCT
admet-1468	198	4	all	all	DET
admet-1468	198	5	the	the	DET
admet-1468	198	6	derivatives	derivative	NOUN
admet-1468	198	7	showed	show	VERB
admet-1468	198	8	certain	certain	ADJ
admet-1468	198	9	selectivity	selectivity	NOUN
admet-1468	198	10	(	(	PUNCT
admet-1468	198	11	more	more	ADJ
admet-1468	198	12	than	than	ADP
admet-1468	198	13	2	2	NUM
admet-1468	198	14	)	)	PUNCT
admet-1468	198	15	and	and	CCONJ
admet-1468	198	16	the	the	DET
admet-1468	198	17	si	si	PROPN
admet-1468	198	18	values	value	NOUN
admet-1468	198	19	entail	entail	VERB
admet-1468	198	20	that	that	SCONJ
admet-1468	198	21	the	the	DET
admet-1468	198	22	test	test	NOUN
admet-1468	198	23	compounds	compound	NOUN
admet-1468	198	24	were	be	AUX
admet-1468	198	25	more	more	ADV
admet-1468	198	26	selective	selective	ADJ
admet-1468	198	27	towards	towards	ADP
admet-1468	198	28	cancer	cancer	NOUN
admet-1468	198	29	cells	cell	NOUN
admet-1468	198	30	than	than	ADP
admet-1468	198	31	the	the	DET
admet-1468	198	32	non	non	ADJ
admet-1468	198	33	-	-	ADJ
admet-1468	198	34	malignant	malignant	ADJ
admet-1468	198	35	cells	cell	NOUN
admet-1468	198	36	.	.	PUNCT
admet-1468	199	1	molecular	molecular	ADJ
admet-1468	199	2	docking	docking	NOUN
admet-1468	199	3	recently	recently	ADV
admet-1468	199	4	,	,	PUNCT
admet-1468	199	5	benzopyran	benzopyran	VERB
admet-1468	199	6	derivatives	derivative	NOUN
admet-1468	199	7	were	be	AUX
admet-1468	199	8	investigated	investigate	VERB
admet-1468	199	9	as	as	ADP
admet-1468	199	10	potent	potent	ADJ
admet-1468	199	11	cox-2	cox-2	ADJ
admet-1468	199	12	inhibitors	inhibitor	NOUN
admet-1468	199	13	and	and	CCONJ
admet-1468	199	14	more	more	ADV
admet-1468	199	15	specifically	specifically	ADV
admet-1468	199	16	,	,	PUNCT
admet-1468	199	17	coumarin	coumarin	NOUN
admet-1468	199	18	derivatives	derivative	NOUN
admet-1468	199	19	were	be	AUX
admet-1468	199	20	proved	prove	VERB
admet-1468	199	21	to	to	PART
admet-1468	199	22	possess	possess	VERB
admet-1468	199	23	potent	potent	ADJ
admet-1468	199	24	anti	anti	ADJ
admet-1468	199	25	-	-	ADJ
admet-1468	199	26	inflammatory	inflammatory	ADJ
admet-1468	199	27	effects	effect	NOUN
admet-1468	199	28	and	and	CCONJ
admet-1468	199	29	,	,	PUNCT
admet-1468	199	30	thus	thus	ADV
admet-1468	199	31	,	,	PUNCT
admet-1468	199	32	were	be	AUX
admet-1468	199	33	evaluated	evaluate	VERB
admet-1468	199	34	as	as	ADP
admet-1468	199	35	cox-2	cox-2	ADJ
admet-1468	199	36	inhibitors	inhibitor	NOUN
admet-1468	199	37	[	[	X
admet-1468	199	38	37	37	NUM
admet-1468	199	39	]	]	PUNCT
admet-1468	199	40	.	.	PUNCT
admet-1468	200	1	our	our	PRON
admet-1468	200	2	interest	interest	NOUN
admet-1468	200	3	in	in	ADP
admet-1468	200	4	the	the	DET
admet-1468	200	5	identification	identification	NOUN
admet-1468	200	6	of	of	ADP
admet-1468	200	7	new	new	ADJ
admet-1468	200	8	cox-2	cox-2	ADJ
admet-1468	200	9	inhibitors	inhibitor	NOUN
admet-1468	200	10	prompted	prompt	VERB
admet-1468	200	11	us	we	PRON
admet-1468	200	12	to	to	PART
admet-1468	200	13	explore	explore	VERB
admet-1468	200	14	the	the	DET
admet-1468	200	15	use	use	NOUN
admet-1468	200	16	of	of	ADP
admet-1468	200	17	the	the	DET
admet-1468	200	18	coumarin	coumarin	NOUN
admet-1468	200	19	framework	framework	NOUN
admet-1468	200	20	for	for	ADP
admet-1468	200	21	the	the	DET
admet-1468	200	22	design	design	NOUN
admet-1468	200	23	of	of	ADP
admet-1468	200	24	this	this	DET
admet-1468	200	25	type	type	NOUN
admet-1468	200	26	of	of	ADP
admet-1468	200	27	inhibitors	inhibitor	NOUN
admet-1468	200	28	[	[	X
admet-1468	200	29	38	38	NUM
admet-1468	200	30	]	]	PUNCT
admet-1468	200	31	.	.	PUNCT
admet-1468	201	1	molecular	molecular	ADJ
admet-1468	201	2	docking	docking	NOUN
admet-1468	201	3	was	be	AUX
admet-1468	201	4	used	use	VERB
admet-1468	201	5	for	for	ADP
admet-1468	201	6	the	the	DET
admet-1468	201	7	exploration	exploration	NOUN
admet-1468	201	8	of	of	ADP
admet-1468	201	9	the	the	DET
admet-1468	201	10	interaction	interaction	NOUN
admet-1468	201	11	between	between	ADP
admet-1468	201	12	a	a	DET
admet-1468	201	13	drug	drug	NOUN
admet-1468	201	14	and	and	CCONJ
admet-1468	201	15	an	an	DET
admet-1468	201	16	enzyme	enzyme	NOUN
admet-1468	201	17	.	.	PUNCT
admet-1468	202	1	the	the	DET
admet-1468	202	2	determined	determined	ADJ
admet-1468	202	3	binding	bind	VERB
admet-1468	202	4	energy	energy	NOUN
admet-1468	202	5	(	(	PUNCT
admet-1468	202	6	b.	b.	PROPN
admet-1468	202	7	e.	e.	PROPN
admet-1468	202	8	)	)	PUNCT
admet-1468	202	9	values	value	NOUN
admet-1468	202	10	and	and	CCONJ
admet-1468	202	11	the	the	DET
admet-1468	202	12	amino	amino	NOUN
admet-1468	202	13	acid	acid	NOUN
admet-1468	202	14	residues	residue	NOUN
admet-1468	202	15	of	of	ADP
admet-1468	202	16	cox-2	cox-2	NOUN
admet-1468	202	17	(	(	PUNCT
admet-1468	202	18	pdb	pdb	PROPN
admet-1468	202	19	i	i	PROPN
admet-1468	202	20	d	d	PROPN
admet-1468	202	21	:	:	PUNCT
admet-1468	202	22	6cox	6cox	X
admet-1468	202	23	)	)	PUNCT
admet-1468	202	24	are	be	AUX
admet-1468	202	25	given	give	VERB
admet-1468	202	26	in	in	ADP
admet-1468	202	27	table	table	NOUN
admet-1468	202	28	3	3	NUM
admet-1468	202	29	.	.	PUNCT
admet-1468	203	1	the	the	DET
admet-1468	203	2	calculated	calculated	ADJ
admet-1468	203	3	binding	bind	VERB
admet-1468	203	4	energies	energy	NOUN
admet-1468	203	5	reveal	reveal	VERB
admet-1468	203	6	that	that	SCONJ
admet-1468	203	7	all	all	DET
admet-1468	203	8	coumarin	coumarin	NOUN
admet-1468	203	9	-	-	PUNCT
admet-1468	203	10	quinone	quinone	NOUN
admet-1468	203	11	hybrids	hybrid	NOUN
admet-1468	203	12	fit	fit	VERB
admet-1468	203	13	favorably	favorably	ADV
admet-1468	203	14	into	into	ADP
admet-1468	203	15	the	the	DET
admet-1468	203	16	cox-2	cox-2	ADJ
admet-1468	203	17	active	active	ADJ
admet-1468	203	18	site	site	NOUN
admet-1468	203	19	displaying	display	VERB
admet-1468	203	20	hydrogen	hydrogen	NOUN
admet-1468	203	21	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	203	22	a.	a.	NOUN
admet-1468	203	23	pangal	pangal	PROPN
admet-1468	203	24	and	and	CCONJ
admet-1468	203	25	k.	k.	PROPN
admet-1468	203	26	ahmed	ahmed	PROPN
admet-1468	203	27	admet	admet	PROPN
admet-1468	203	28	&	&	CCONJ
admet-1468	203	29	dmpk	dmpk	PROPN
admet-1468	203	30	11(1	11(1	NUM
admet-1468	203	31	)	)	PUNCT
admet-1468	203	32	(	(	PUNCT
admet-1468	203	33	2023	2023	NUM
admet-1468	203	34	)	)	PUNCT
admet-1468	203	35	81	81	NUM
admet-1468	203	36	-	-	SYM
admet-1468	203	37	96	96	NUM
admet-1468	203	38	90	90	NUM
admet-1468	203	39	bonding	bonding	NOUN
admet-1468	203	40	with	with	ADP
admet-1468	203	41	various	various	ADJ
admet-1468	203	42	amino	amino	NOUN
admet-1468	203	43	acid	acid	NOUN
admet-1468	203	44	residues	residue	NOUN
admet-1468	203	45	of	of	ADP
admet-1468	203	46	the	the	DET
admet-1468	203	47	target	target	NOUN
admet-1468	203	48	protein	protein	NOUN
admet-1468	203	49	.	.	PUNCT
admet-1468	204	1	table	table	NOUN
admet-1468	204	2	3	3	NUM
admet-1468	204	3	.	.	PUNCT
admet-1468	205	1	binding	bind	VERB
admet-1468	205	2	energies	energy	NOUN
admet-1468	205	3	and	and	CCONJ
admet-1468	205	4	the	the	DET
admet-1468	205	5	interacting	interact	VERB
admet-1468	205	6	surfaces	surface	NOUN
admet-1468	205	7	of	of	ADP
admet-1468	205	8	the	the	DET
admet-1468	205	9	compounds	compound	NOUN
admet-1468	205	10	no	no	PROPN
admet-1468	205	11	.	.	PUNCT
admet-1468	205	12	code	code	PROPN
admet-1468	205	13	b.e	b.e	PROPN
admet-1468	205	14	.	.	PROPN
admet-1468	205	15	in	in	ADP
admet-1468	205	16	kcal	kcal	PROPN
admet-1468	205	17	/	/	SYM
admet-1468	205	18	mol	mol	ADP
admet-1468	205	19	amino	amino	NOUN
admet-1468	205	20	acid	acid	NOUN
admet-1468	205	21	residue	residue	NOUN
admet-1468	205	22	bond	bond	NOUN
admet-1468	205	23	length	length	NOUN
admet-1468	205	24	in	in	ADP
admet-1468	205	25	å	å	PROPN
admet-1468	205	26	1	1	NUM
admet-1468	205	27	dtbsa	dtbsa	NOUN
admet-1468	205	28	-8.7	-8.7	ADJ
admet-1468	205	29	ser-471	ser-471	NOUN
admet-1468	205	30	,	,	PUNCT
admet-1468	205	31	asn-43	asn-43	ADP
admet-1468	205	32	3.2	3.2	NUM
admet-1468	205	33	,	,	PUNCT
admet-1468	205	34	2.8	2.8	NUM
admet-1468	205	35	,	,	PUNCT
admet-1468	205	36	3.4	3.4	NUM
admet-1468	205	37	2	2	NUM
admet-1468	205	38	dtbsc	dtbsc	NOUN
admet-1468	205	39	-11.1	-11.1	PROPN
admet-1468	205	40	cys-47	cys-47	PROPN
admet-1468	205	41	3.0	3.0	NUM
admet-1468	205	42	3	3	NUM
admet-1468	205	43	dtbsb	dtbsb	NOUN
admet-1468	205	44	-11.1	-11.1	PROPN
admet-1468	205	45	cys-47	cys-47	NUM
admet-1468	205	46	3.0	3.0	NUM
admet-1468	205	47	4	4	NUM
admet-1468	205	48	dtbsn	dtbsn	NOUN
admet-1468	205	49	-11.3	-11.3	NUM
admet-1468	205	50	cys-47	cys-47	NUM
admet-1468	205	51	2.8	2.8	NUM
admet-1468	205	52	,	,	PUNCT
admet-1468	205	53	2.9	2.9	NUM
admet-1468	205	54	the	the	DET
admet-1468	205	55	docking	docking	NOUN
admet-1468	205	56	ribbon	ribbon	NOUN
admet-1468	205	57	structures	structure	NOUN
admet-1468	205	58	of	of	ADP
admet-1468	205	59	the	the	DET
admet-1468	205	60	cox-2	cox-2	ADJ
admet-1468	205	61	(	(	PUNCT
admet-1468	205	62	6cox	6cox	X
admet-1468	205	63	)	)	PUNCT
admet-1468	205	64	protein	protein	NOUN
admet-1468	205	65	with	with	ADP
admet-1468	205	66	bound	bind	VERB
admet-1468	205	67	coumarin	coumarin	NOUN
admet-1468	205	68	-	-	PUNCT
admet-1468	205	69	quinone	quinone	NOUN
admet-1468	205	70	hybrids	hybrid	NOUN
admet-1468	205	71	are	be	AUX
admet-1468	205	72	given	give	VERB
admet-1468	205	73	in	in	ADP
admet-1468	205	74	figure	figure	NOUN
admet-1468	205	75	5	5	NUM
admet-1468	205	76	.	.	PUNCT
admet-1468	206	1	the	the	DET
admet-1468	206	2	binding	bind	VERB
admet-1468	206	3	interactions	interaction	NOUN
admet-1468	206	4	for	for	ADP
admet-1468	206	5	these	these	DET
admet-1468	206	6	hydrazones	hydrazone	NOUN
admet-1468	206	7	involve	involve	VERB
admet-1468	206	8	-nh	-nh	ADP
admet-1468	206	9	functionalities	functionality	NOUN
admet-1468	206	10	.	.	PUNCT
admet-1468	207	1	the	the	DET
admet-1468	207	2	best	well	ADV
admet-1468	207	3	binding	bind	VERB
admet-1468	207	4	energy	energy	NOUN
admet-1468	207	5	of	of	ADP
admet-1468	207	6	-11.3	-11.3	PROPN
admet-1468	207	7	kcal	kcal	PROPN
admet-1468	207	8	/	/	SYM
admet-1468	207	9	mol	mol	PROPN
admet-1468	207	10	was	be	AUX
admet-1468	207	11	exhibited	exhibit	VERB
admet-1468	207	12	by	by	ADP
admet-1468	207	13	dtbsn	dtbsn	NOUN
admet-1468	207	14	followed	follow	VERB
admet-1468	207	15	by	by	ADP
admet-1468	207	16	dtbsb	dtbsb	NOUN
admet-1468	207	17	,	,	PUNCT
admet-1468	207	18	dtbsc	dtbsc	NOUN
admet-1468	207	19	and	and	CCONJ
admet-1468	207	20	dtbsa	dtbsa	NOUN
admet-1468	207	21	.	.	PUNCT
admet-1468	208	1	thus	thus	ADV
admet-1468	208	2	,	,	PUNCT
admet-1468	208	3	dtbsn	dtbsn	NOUN
admet-1468	208	4	has	have	VERB
admet-1468	208	5	stronger	strong	ADJ
admet-1468	208	6	binding	binding	ADJ
admet-1468	208	7	interactions	interaction	NOUN
admet-1468	208	8	with	with	ADP
admet-1468	208	9	cox-2	cox-2	NUM
admet-1468	208	10	than	than	ADP
admet-1468	208	11	the	the	DET
admet-1468	208	12	other	other	ADJ
admet-1468	208	13	derivatives	derivative	NOUN
admet-1468	208	14	.	.	PUNCT
admet-1468	209	1	the	the	DET
admet-1468	209	2	compounds	compound	NOUN
admet-1468	209	3	show	show	VERB
admet-1468	209	4	hydrogen	hydrogen	NOUN
admet-1468	209	5	bonding	bonding	NOUN
admet-1468	209	6	interactions	interaction	NOUN
admet-1468	209	7	with	with	ADP
admet-1468	209	8	amino	amino	NOUN
admet-1468	209	9	acid	acid	NOUN
admet-1468	209	10	residues	residue	NOUN
admet-1468	209	11	and	and	CCONJ
admet-1468	209	12	the	the	DET
admet-1468	209	13	hydrogen	hydrogen	NOUN
admet-1468	209	14	bond	bond	NOUN
admet-1468	209	15	distances	distance	NOUN
admet-1468	209	16	of	of	ADP
admet-1468	209	17	2.8	2.8	NUM
admet-1468	209	18	and	and	CCONJ
admet-1468	209	19	2.9	2.9	NUM
admet-1468	209	20	å	å	NOUN
admet-1468	209	21	lengths	length	NOUN
admet-1468	209	22	indicate	indicate	VERB
admet-1468	209	23	strong	strong	ADJ
admet-1468	209	24	drug	drug	NOUN
admet-1468	209	25	-	-	PUNCT
admet-1468	209	26	enzyme	enzyme	NOUN
admet-1468	209	27	interactions	interaction	NOUN
admet-1468	209	28	.	.	PUNCT
admet-1468	210	1	these	these	DET
admet-1468	210	2	interactions	interaction	NOUN
admet-1468	210	3	lead	lead	VERB
admet-1468	210	4	to	to	ADP
admet-1468	210	5	a	a	DET
admet-1468	210	6	stabilization	stabilization	NOUN
admet-1468	210	7	of	of	ADP
admet-1468	210	8	the	the	DET
admet-1468	210	9	bound	bind	VERB
admet-1468	210	10	compounds	compound	NOUN
admet-1468	210	11	in	in	ADP
admet-1468	210	12	the	the	DET
admet-1468	210	13	protein	protein	NOUN
admet-1468	210	14	cavity	cavity	NOUN
admet-1468	210	15	.	.	PUNCT
admet-1468	211	1	the	the	DET
admet-1468	211	2	docking	docking	NOUN
admet-1468	211	3	results	result	NOUN
admet-1468	211	4	show	show	VERB
admet-1468	211	5	that	that	SCONJ
admet-1468	211	6	the	the	DET
admet-1468	211	7	hybrid	hybrid	ADJ
admet-1468	211	8	compounds	compound	NOUN
admet-1468	211	9	may	may	AUX
admet-1468	211	10	have	have	VERB
admet-1468	211	11	significant	significant	ADJ
admet-1468	211	12	interactions	interaction	NOUN
admet-1468	211	13	with	with	ADP
admet-1468	211	14	human	human	ADJ
admet-1468	211	15	cox-2	cox-2	NOUN
admet-1468	211	16	in	in	ADP
admet-1468	211	17	vitro	vitro	X
admet-1468	211	18	.	.	PUNCT
admet-1468	212	1	figure	figure	NOUN
admet-1468	212	2	5	5	NUM
admet-1468	212	3	.	.	PUNCT
admet-1468	213	1	binding	bind	VERB
admet-1468	213	2	of	of	ADP
admet-1468	213	3	coumarin	coumarin	NOUN
admet-1468	213	4	-	-	PUNCT
admet-1468	213	5	quinone	quinone	NOUN
admet-1468	213	6	hybrids	hybrid	NOUN
admet-1468	213	7	into	into	ADP
admet-1468	213	8	the	the	DET
admet-1468	213	9	active	active	ADJ
admet-1468	213	10	site	site	NOUN
admet-1468	213	11	of	of	ADP
admet-1468	213	12	cox-2	cox-2	PRON
admet-1468	213	13	(	(	PUNCT
admet-1468	213	14	6cox	6cox	PROPN
admet-1468	213	15	)	)	PUNCT
admet-1468	213	16	admet	admet	NOUN
admet-1468	213	17	and	and	CCONJ
admet-1468	213	18	pharmacokinetic	pharmacokinetic	ADJ
admet-1468	213	19	studies	study	NOUN
admet-1468	213	20	admet	admet	PROPN
admet-1468	213	21	predictor	predictor	PROPN
admet-1468	213	22	is	be	AUX
admet-1468	213	23	a	a	DET
admet-1468	213	24	computer	computer	NOUN
admet-1468	213	25	program	program	NOUN
admet-1468	213	26	designed	design	VERB
admet-1468	213	27	to	to	PART
admet-1468	213	28	predict	predict	VERB
admet-1468	213	29	pharmacokinetic	pharmacokinetic	ADJ
admet-1468	213	30	parameters	parameter	NOUN
admet-1468	213	31	of	of	ADP
admet-1468	213	32	drug	drug	NOUN
admet-1468	213	33	-	-	PUNCT
admet-1468	213	34	like	like	ADJ
admet-1468	213	35	compounds	compound	NOUN
admet-1468	213	36	like	like	ADP
admet-1468	213	37	absorption	absorption	NOUN
admet-1468	213	38	,	,	PUNCT
admet-1468	213	39	distribution	distribution	NOUN
admet-1468	213	40	,	,	PUNCT
admet-1468	213	41	metabolism	metabolism	NOUN
admet-1468	213	42	,	,	PUNCT
admet-1468	213	43	excretion	excretion	NOUN
admet-1468	213	44	and	and	CCONJ
admet-1468	213	45	toxicity	toxicity	NOUN
admet-1468	213	46	(	(	PUNCT
admet-1468	213	47	admet	admet	PROPN
admet-1468	213	48	)	)	PUNCT
admet-1468	213	49	based	base	VERB
admet-1468	213	50	on	on	ADP
admet-1468	213	51	their	their	PRON
admet-1468	213	52	molecular	molecular	ADJ
admet-1468	213	53	structures	structure	NOUN
admet-1468	213	54	.	.	PUNCT
admet-1468	214	1	an	an	DET
admet-1468	214	2	amenable	amenable	ADJ
admet-1468	214	3	pharmacokinetic	pharmacokinetic	ADJ
admet-1468	214	4	profile	profile	NOUN
admet-1468	214	5	with	with	ADP
admet-1468	214	6	high	high	ADJ
admet-1468	214	7	bioactivity	bioactivity	NOUN
admet-1468	214	8	and	and	CCONJ
admet-1468	214	9	low	low	ADJ
admet-1468	214	10	toxicities	toxicity	NOUN
admet-1468	214	11	is	be	AUX
admet-1468	214	12	essential	essential	ADJ
admet-1468	214	13	for	for	ADP
admet-1468	214	14	a	a	DET
admet-1468	214	15	compound	compound	NOUN
admet-1468	214	16	,	,	PUNCT
admet-1468	214	17	which	which	PRON
admet-1468	214	18	should	should	AUX
admet-1468	214	19	be	be	AUX
admet-1468	214	20	investigated	investigate	VERB
admet-1468	214	21	during	during	ADP
admet-1468	214	22	drug	drug	NOUN
admet-1468	214	23	discovery	discovery	NOUN
admet-1468	214	24	to	to	PART
admet-1468	214	25	reduce	reduce	VERB
admet-1468	214	26	the	the	DET
admet-1468	214	27	wastage	wastage	NOUN
admet-1468	214	28	of	of	ADP
admet-1468	214	29	time	time	NOUN
admet-1468	214	30	and	and	CCONJ
admet-1468	214	31	resources	resource	NOUN
admet-1468	214	32	[	[	X
admet-1468	214	33	39	39	NUM
admet-1468	214	34	-	-	SYM
admet-1468	214	35	40	40	NUM
admet-1468	214	36	]	]	PUNCT
admet-1468	214	37	.	.	PUNCT
admet-1468	215	1	the	the	DET
admet-1468	215	2	pharmacokinetic	pharmacokinetic	ADJ
admet-1468	215	3	profile	profile	NOUN
admet-1468	215	4	and	and	CCONJ
admet-1468	215	5	drug	drug	NOUN
admet-1468	215	6	-	-	PUNCT
admet-1468	215	7	like	like	ADJ
admet-1468	215	8	properties	property	NOUN
admet-1468	215	9	of	of	ADP
admet-1468	215	10	the	the	DET
admet-1468	215	11	new	new	ADJ
admet-1468	215	12	hybrid	hybrid	ADJ
admet-1468	215	13	compounds	compound	NOUN
admet-1468	215	14	were	be	AUX
admet-1468	215	15	predicted	predict	VERB
admet-1468	215	16	using	use	VERB
admet-1468	215	17	the	the	DET
admet-1468	215	18	online	online	ADJ
admet-1468	215	19	sources	source	NOUN
admet-1468	215	20	pkcsm	pkcsm	NOUN
admet-1468	215	21	and	and	CCONJ
admet-1468	215	22	swissadme	swissadme	NOUN
admet-1468	215	23	to	to	PART
admet-1468	215	24	reassure	reassure	VERB
admet-1468	215	25	the	the	DET
admet-1468	215	26	drug	drug	NOUN
admet-1468	215	27	potential	potential	NOUN
admet-1468	215	28	.	.	PUNCT
admet-1468	216	1	the	the	DET
admet-1468	216	2	predicted	predict	VERB
admet-1468	216	3	values	value	NOUN
admet-1468	216	4	are	be	AUX
admet-1468	216	5	shown	show	VERB
admet-1468	216	6	in	in	ADP
admet-1468	216	7	table	table	NOUN
admet-1468	216	8	4	4	NUM
admet-1468	216	9	.	.	PUNCT
admet-1468	217	1	the	the	DET
admet-1468	217	2	evaluated	evaluated	ADJ
admet-1468	217	3	parameters	parameter	NOUN
admet-1468	217	4	showed	show	VERB
admet-1468	217	5	that	that	SCONJ
admet-1468	217	6	the	the	DET
admet-1468	217	7	molecules	molecule	NOUN
admet-1468	217	8	have	have	VERB
admet-1468	217	9	considerable	considerable	ADJ
admet-1468	217	10	solubility	solubility	NOUN
admet-1468	217	11	in	in	ADP
admet-1468	217	12	water	water	NOUN
admet-1468	217	13	.	.	PUNCT
admet-1468	218	1	log	log	PROPN
admet-1468	218	2	s	s	PART
admet-1468	218	3	(	(	PUNCT
admet-1468	218	4	s	s	PROPN
admet-1468	218	5	in	in	ADP
admet-1468	218	6	mol	mol	PROPN
admet-1468	218	7	/	/	SYM
admet-1468	218	8	l	l	NOUN
admet-1468	218	9	)	)	PUNCT
admet-1468	218	10	is	be	AUX
admet-1468	218	11	a	a	DET
admet-1468	218	12	parameter	parameter	NOUN
admet-1468	218	13	used	use	VERB
admet-1468	218	14	to	to	PART
admet-1468	218	15	evaluate	evaluate	VERB
admet-1468	218	16	aqueous	aqueous	ADJ
admet-1468	218	17	solubility	solubility	NOUN
admet-1468	218	18	.	.	PUNCT
admet-1468	219	1	all	all	DET
admet-1468	219	2	compounds	compound	NOUN
admet-1468	219	3	have	have	VERB
admet-1468	219	4	good	good	ADJ
admet-1468	219	5	solubility	solubility	NOUN
admet-1468	219	6	values	value	NOUN
admet-1468	219	7	ranging	range	VERB
admet-1468	219	8	from	from	ADP
admet-1468	219	9	-5.287	-5.287	ADP
admet-1468	219	10	to	to	ADP
admet-1468	219	11	-5.938	-5.938	PROPN
admet-1468	219	12	mol	mol	PROPN
admet-1468	219	13	/	/	SYM
admet-1468	219	14	l.	l.	PROPN
admet-1468	219	15	dtbsb	dtbsb	PROPN
admet-1468	219	16	is	be	AUX
admet-1468	219	17	more	more	ADV
admet-1468	219	18	soluble	soluble	ADJ
admet-1468	219	19	in	in	ADP
admet-1468	219	20	water	water	NOUN
admet-1468	219	21	than	than	ADP
admet-1468	219	22	all	all	DET
admet-1468	219	23	other	other	ADJ
admet-1468	219	24	analogs	analog	NOUN
admet-1468	219	25	.	.	PUNCT
admet-1468	220	1	a	a	DET
admet-1468	220	2	papp	papp	NOUN
admet-1468	220	3	coefficient	coefficient	NOUN
admet-1468	220	4	greater	great	ADJ
admet-1468	220	5	than	than	ADP
admet-1468	220	6	0.90	0.90	NUM
admet-1468	220	7	indicates	indicate	VERB
admet-1468	220	8	that	that	SCONJ
admet-1468	220	9	that	that	DET
admet-1468	220	10	compound	compound	NOUN
admet-1468	220	11	has	have	VERB
admet-1468	220	12	high	high	ADJ
admet-1468	220	13	caco-2	caco-2	NUM
admet-1468	220	14	permeability	permeability	NOUN
admet-1468	220	15	and	and	CCONJ
admet-1468	220	16	is	be	AUX
admet-1468	220	17	easily	easily	ADV
admet-1468	220	18	absorbed	absorb	VERB
admet-1468	220	19	in	in	ADP
admet-1468	220	20	the	the	DET
admet-1468	220	21	admet	admet	PROPN
admet-1468	220	22	&	&	CCONJ
admet-1468	220	23	dmpk	dmpk	PROPN
admet-1468	220	24	11(1	11(1	NUM
admet-1468	220	25	)	)	PUNCT
admet-1468	220	26	(	(	PUNCT
admet-1468	220	27	2023	2023	NUM
admet-1468	220	28	)	)	PUNCT
admet-1468	220	29	81	81	NUM
admet-1468	220	30	-	-	SYM
admet-1468	220	31	96	96	NUM
admet-1468	220	32	coumarin	coumarin	NOUN
admet-1468	220	33	-	-	PUNCT
admet-1468	220	34	quinone	quinone	NOUN
admet-1468	220	35	hybrids	hybrid	NOUN
admet-1468	220	36	doi	doi	NOUN
admet-1468	220	37	:	:	PUNCT
admet-1468	220	38	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	220	39	91	91	NUM
admet-1468	220	40	gastrointestinal	gastrointestinal	ADJ
admet-1468	220	41	tract	tract	NOUN
admet-1468	220	42	.	.	PUNCT
admet-1468	221	1	however	however	ADV
admet-1468	221	2	,	,	PUNCT
admet-1468	221	3	all	all	DET
admet-1468	221	4	test	test	NOUN
admet-1468	221	5	compounds	compound	NOUN
admet-1468	221	6	exhibited	exhibit	VERB
admet-1468	221	7	lower	low	ADJ
admet-1468	221	8	papp	papp	NOUN
admet-1468	221	9	coefficients	coefficient	NOUN
admet-1468	221	10	.	.	PUNCT
admet-1468	222	1	dtbsn	dtbsn	NOUN
admet-1468	222	2	showed	show	VERB
admet-1468	222	3	the	the	DET
admet-1468	222	4	highest	high	ADJ
admet-1468	222	5	value	value	NOUN
admet-1468	222	6	among	among	ADP
admet-1468	222	7	all	all	DET
admet-1468	222	8	analogs	analog	NOUN
admet-1468	222	9	,	,	PUNCT
admet-1468	222	10	indicating	indicate	VERB
admet-1468	222	11	a	a	DET
admet-1468	222	12	rather	rather	ADV
admet-1468	222	13	good	good	ADJ
admet-1468	222	14	absorption	absorption	NOUN
admet-1468	222	15	.	.	PUNCT
admet-1468	223	1	drugs	drug	NOUN
admet-1468	223	2	with	with	ADP
admet-1468	223	3	less	less	ADJ
admet-1468	223	4	than	than	ADP
admet-1468	223	5	30	30	NUM
admet-1468	223	6	%	%	NOUN
admet-1468	223	7	intestinal	intestinal	ADJ
admet-1468	223	8	absorption	absorption	NOUN
admet-1468	223	9	are	be	AUX
admet-1468	223	10	considered	consider	VERB
admet-1468	223	11	to	to	PART
admet-1468	223	12	be	be	AUX
admet-1468	223	13	poorly	poorly	ADV
admet-1468	223	14	absorbed	absorb	VERB
admet-1468	223	15	in	in	ADP
admet-1468	223	16	the	the	DET
admet-1468	223	17	intestine	intestine	NOUN
admet-1468	223	18	.	.	PUNCT
admet-1468	224	1	all	all	DET
admet-1468	224	2	analogs	analog	NOUN
admet-1468	224	3	were	be	AUX
admet-1468	224	4	found	find	VERB
admet-1468	224	5	to	to	PART
admet-1468	224	6	have	have	VERB
admet-1468	224	7	good	good	ADJ
admet-1468	224	8	intestinal	intestinal	ADJ
admet-1468	224	9	absorption	absorption	NOUN
admet-1468	224	10	,	,	PUNCT
admet-1468	224	11	up	up	ADP
admet-1468	224	12	to	to	PART
admet-1468	224	13	94	94	NUM
admet-1468	224	14	%	%	NOUN
admet-1468	224	15	.	.	PUNCT
admet-1468	225	1	with	with	ADP
admet-1468	225	2	the	the	DET
admet-1468	225	3	log	log	NOUN
admet-1468	225	4	kp	kp	PROPN
admet-1468	225	5	>	>	PUNCT
admet-1468	225	6	-2.5	-2.5	PROPN
admet-1468	225	7	,	,	PUNCT
admet-1468	225	8	the	the	DET
admet-1468	225	9	drug	drug	NOUN
admet-1468	225	10	is	be	AUX
admet-1468	225	11	considered	consider	VERB
admet-1468	225	12	to	to	PART
admet-1468	225	13	have	have	VERB
admet-1468	225	14	relatively	relatively	ADV
admet-1468	225	15	low	low	ADJ
admet-1468	225	16	skin	skin	NOUN
admet-1468	225	17	permeability	permeability	NOUN
admet-1468	225	18	,	,	PUNCT
admet-1468	225	19	and	and	CCONJ
admet-1468	225	20	all	all	DET
admet-1468	225	21	analogs	analog	NOUN
admet-1468	225	22	showed	show	VERB
admet-1468	225	23	low	low	ADJ
admet-1468	225	24	skin	skin	NOUN
admet-1468	225	25	permeability	permeability	NOUN
admet-1468	225	26	.	.	PUNCT
admet-1468	226	1	table	table	NOUN
admet-1468	226	2	4	4	NUM
admet-1468	226	3	.	.	PUNCT
admet-1468	227	1	admet	admet	PROPN
admet-1468	227	2	properties	property	NOUN
admet-1468	227	3	of	of	ADP
admet-1468	227	4	coumarin	coumarin	NOUN
admet-1468	227	5	-	-	PUNCT
admet-1468	227	6	quinone	quinone	NOUN
admet-1468	227	7	hybrids	hybrid	NOUN
admet-1468	227	8	calculated	calculate	VERB
admet-1468	227	9	with	with	ADP
admet-1468	227	10	pkcsm	pkcsm	NOUN
admet-1468	227	11	online	online	ADJ
admet-1468	227	12	tool	tool	NOUN
admet-1468	227	13	property	property	NOUN
admet-1468	227	14	model	model	NOUN
admet-1468	227	15	name	name	NOUN
admet-1468	227	16	dtbsa	dtbsa	VERB
admet-1468	227	17	dtbsc	dtbsc	PROPN
admet-1468	227	18	dtbsb	dtbsb	PROPN
admet-1468	227	19	dtbsn	dtbsn	PROPN
admet-1468	227	20	absorption	absorption	NOUN
admet-1468	227	21	water	water	NOUN
admet-1468	227	22	solubilitya	solubilitya	NOUN
admet-1468	227	23	-5.287	-5.287	PUNCT
admet-1468	227	24	-5.864	-5.864	NUM
admet-1468	227	25	-5.938	-5.938	ADJ
admet-1468	227	26	-5.373	-5.373	PUNCT
admet-1468	227	27	caco-2	caco-2	NUM
admet-1468	227	28	permeabilityb	permeabilityb	VERB
admet-1468	227	29	0.597	0.597	NUM
admet-1468	227	30	0.611	0.611	NUM
admet-1468	227	31	0.602	0.602	NUM
admet-1468	227	32	0.632	0.632	NUM
admet-1468	227	33	intestinal	intestinal	ADJ
admet-1468	227	34	absorption	absorption	NOUN
admet-1468	227	35	(	(	PUNCT
admet-1468	227	36	human)c	human)c	PROPN
admet-1468	227	37	93.878	93.878	NUM
admet-1468	227	38	93.183	93.183	NUM
admet-1468	227	39	93.116	93.116	NUM
admet-1468	227	40	94.408	94.408	NUM
admet-1468	227	41	skin	skin	NOUN
admet-1468	227	42	permeabilityd	permeabilityd	NOUN
admet-1468	227	43	-2.877	-2.877	NUM
admet-1468	227	44	-2.876	-2.876	X
admet-1468	227	45	-2.873	-2.873	PUNCT
admet-1468	227	46	-2.754	-2.754	PUNCT
admet-1468	227	47	distribution	distribution	NOUN
admet-1468	227	48	vdss	vdss	ADV
admet-1468	227	49	(	(	PUNCT
admet-1468	227	50	human)e	human)e	PROPN
admet-1468	227	51	-0.01	-0.01	NUM
admet-1468	227	52	-0.031	-0.031	NOUN
admet-1468	227	53	-0.021	-0.021	NOUN
admet-1468	227	54	-0.188	-0.188	PROPN
admet-1468	227	55	bbb	bbb	X
admet-1468	227	56	permeabilityf	permeabilityf	PRON
admet-1468	227	57	0.139	0.139	NUM
admet-1468	227	58	-0.015	-0.015	PUNCT
admet-1468	227	59	-0.024	-0.024	PUNCT
admet-1468	227	60	-0.227	-0.227	PUNCT
admet-1468	227	61	cns	cns	PROPN
admet-1468	227	62	permeabilityg	permeabilityg	NOUN
admet-1468	227	63	-1.665	-1.665	PROPN
admet-1468	227	64	-1.553	-1.553	NOUN
admet-1468	227	65	-1.531	-1.531	PUNCT
admet-1468	227	66	-1.888	-1.888	PUNCT
admet-1468	227	67	metabolism	metabolism	NOUN
admet-1468	227	68	cyp2d6	cyp2d6	NOUN
admet-1468	227	69	inhibitorh	inhibitorh	VERB
admet-1468	227	70	no	no	PRON
admet-1468	227	71	no	no	INTJ
admet-1468	228	1	no	no	INTJ
admet-1468	229	1	no	no	DET
admet-1468	229	2	cyp3a4	cyp3a4	NOUN
admet-1468	229	3	inhibitorh	inhibitorh	VERB
admet-1468	230	1	yes	yes	INTJ
admet-1468	231	1	yes	yes	INTJ
admet-1468	232	1	yes	yes	INTJ
admet-1468	233	1	yes	yes	INTJ
admet-1468	233	2	excretion	excretion	NOUN
admet-1468	233	3	total	total	NOUN
admet-1468	233	4	clearancei	clearancei	NOUN
admet-1468	233	5	0.598	0.598	NUM
admet-1468	233	6	-0.373	-0.373	SYM
admet-1468	233	7	-0.395	-0.395	PROPN
admet-1468	233	8	0.57	0.57	NUM
admet-1468	233	9	toxicity	toxicity	NOUN
admet-1468	233	10	oral	oral	ADJ
admet-1468	233	11	rat	rat	NOUN
admet-1468	233	12	acute	acute	NOUN
admet-1468	233	13	toxicityj	toxicityj	NOUN
admet-1468	233	14	2.896	2.896	NUM
admet-1468	233	15	3.035	3.035	NUM
admet-1468	233	16	3.04	3.04	NUM
admet-1468	233	17	2.797	2.797	NUM
admet-1468	233	18	oral	oral	ADJ
admet-1468	233	19	rat	rat	NOUN
admet-1468	233	20	chronic	chronic	NOUN
admet-1468	233	21	toxicityk	toxicityk	VERB
admet-1468	233	22	1.367	1.367	NUM
admet-1468	233	23	1.239	1.239	NUM
admet-1468	233	24	1.211	1.211	NUM
admet-1468	233	25	1.812	1.812	NUM
admet-1468	233	26	hepatotoxicityh	hepatotoxicityh	NOUN
admet-1468	234	1	yes	yes	INTJ
admet-1468	235	1	yes	yes	INTJ
admet-1468	236	1	yes	yes	INTJ
admet-1468	237	1	yes	yes	INTJ
admet-1468	237	2	skin	skin	NOUN
admet-1468	237	3	sensitizationh	sensitizationh	NOUN
admet-1468	238	1	no	no	INTJ
admet-1468	238	2	no	no	INTJ
admet-1468	238	3	no	no	INTJ
admet-1468	238	4	no	no	DET
admet-1468	238	5	a(log	a(log	PROPN
admet-1468	238	6	mol	mol	PROPN
admet-1468	238	7	/	/	SYM
admet-1468	238	8	l	l	NOUN
admet-1468	238	9	)	)	PUNCT
admet-1468	238	10	,	,	PUNCT
admet-1468	238	11	b(log	b(log	NOUN
admet-1468	238	12	papp	papp	NOUN
admet-1468	238	13	in	in	ADP
admet-1468	238	14	10	10	NUM
admet-1468	238	15	-	-	SYM
admet-1468	238	16	6	6	NUM
admet-1468	238	17	cm	cm	NOUN
admet-1468	238	18	/	/	SYM
admet-1468	238	19	s	s	NOUN
admet-1468	238	20	)	)	PUNCT
admet-1468	238	21	,	,	PUNCT
admet-1468	238	22	c(%	c(%	NOUN
admet-1468	238	23	absorbed	absorb	VERB
admet-1468	238	24	)	)	PUNCT
admet-1468	238	25	,	,	PUNCT
admet-1468	238	26	d(log	d(log	PROPN
admet-1468	238	27	kp	kp	PROPN
admet-1468	238	28	)	)	PUNCT
admet-1468	238	29	,	,	PUNCT
admet-1468	238	30	e(log	e(log	PROPN
admet-1468	238	31	l	l	PROPN
admet-1468	238	32	/	/	SYM
admet-1468	238	33	kg	kg	PROPN
admet-1468	238	34	)	)	PUNCT
admet-1468	238	35	,	,	PUNCT
admet-1468	238	36	f(fu	f(fu	PROPN
admet-1468	238	37	)	)	PUNCT
admet-1468	238	38	,	,	PUNCT
admet-1468	238	39	g(log	g(log	PROPN
admet-1468	238	40	ps	ps	PROPN
admet-1468	238	41	)	)	PUNCT
admet-1468	238	42	,	,	PUNCT
admet-1468	238	43	h(yes	h(yes	X
admet-1468	238	44	/	/	SYM
admet-1468	238	45	no	no	NOUN
admet-1468	238	46	)	)	PUNCT
admet-1468	238	47	,	,	PUNCT
admet-1468	238	48	i(log	i(log	VERB
admet-1468	238	49	ml	ml	PROPN
admet-1468	238	50	/	/	SYM
admet-1468	238	51	min	min	NOUN
admet-1468	238	52	/	/	SYM
admet-1468	238	53	kg	kg	PROPN
admet-1468	238	54	)	)	PUNCT
admet-1468	238	55	,	,	PUNCT
admet-1468	239	1	j(ld50	j(ld50	PROPN
admet-1468	239	2	in	in	ADP
admet-1468	239	3	mol	mol	PROPN
admet-1468	239	4	/	/	SYM
admet-1468	239	5	kg	kg	PROPN
admet-1468	239	6	)	)	PUNCT
admet-1468	239	7	,	,	PUNCT
admet-1468	239	8	k(loael	k(loael	PROPN
admet-1468	239	9	in	in	ADP
admet-1468	239	10	log	log	PROPN
admet-1468	239	11	mg	mg	PROPN
admet-1468	239	12	/	/	SYM
admet-1468	239	13	kg_bw	kg_bw	PROPN
admet-1468	239	14	/	/	SYM
admet-1468	239	15	day	day	NOUN
admet-1468	239	16	)	)	PUNCT
admet-1468	239	17	the	the	DET
admet-1468	239	18	hybrid	hybrid	ADJ
admet-1468	239	19	dtbsn	dtbsn	NOUN
admet-1468	239	20	exhibited	exhibit	VERB
admet-1468	239	21	a	a	DET
admet-1468	239	22	distribution	distribution	NOUN
admet-1468	239	23	volume	volume	NOUN
admet-1468	239	24	within	within	ADP
admet-1468	239	25	the	the	DET
admet-1468	239	26	range	range	NOUN
admet-1468	239	27	(	(	PUNCT
admet-1468	239	28	-0.15	-0.15	NUM
admet-1468	239	29	to	to	ADP
admet-1468	239	30	0.45	0.45	NUM
admet-1468	239	31	)	)	PUNCT
admet-1468	239	32	,	,	PUNCT
admet-1468	239	33	which	which	PRON
admet-1468	239	34	will	will	AUX
admet-1468	239	35	allow	allow	VERB
admet-1468	239	36	a	a	DET
admet-1468	239	37	good	good	ADJ
admet-1468	239	38	distribution	distribution	NOUN
admet-1468	239	39	of	of	ADP
admet-1468	239	40	this	this	DET
admet-1468	239	41	drug	drug	NOUN
admet-1468	239	42	within	within	ADP
admet-1468	239	43	tissues	tissue	NOUN
admet-1468	239	44	.	.	PUNCT
admet-1468	240	1	the	the	DET
admet-1468	240	2	analog	analog	NOUN
admet-1468	240	3	dtbsa	dtbsa	NOUN
admet-1468	240	4	can	can	AUX
admet-1468	240	5	only	only	ADV
admet-1468	240	6	cross	cross	VERB
admet-1468	240	7	the	the	DET
admet-1468	240	8	blood	blood	NOUN
admet-1468	240	9	-	-	PUNCT
admet-1468	240	10	brain	brain	NOUN
admet-1468	240	11	barrier	barrier	NOUN
admet-1468	240	12	,	,	PUNCT
admet-1468	240	13	while	while	SCONJ
admet-1468	240	14	other	other	ADJ
admet-1468	240	15	analogs	analog	NOUN
admet-1468	240	16	did	do	AUX
admet-1468	240	17	not	not	PART
admet-1468	240	18	cross	cross	VERB
admet-1468	240	19	the	the	DET
admet-1468	240	20	membrane	membrane	NOUN
admet-1468	240	21	as	as	SCONJ
admet-1468	240	22	the	the	DET
admet-1468	240	23	log	log	NOUN
admet-1468	240	24	bb	bb	NOUN
admet-1468	240	25	is	be	AUX
admet-1468	240	26	less	less	ADJ
admet-1468	240	27	than	than	ADP
admet-1468	240	28	-1	-1	ADJ
admet-1468	240	29	.	.	PUNCT
admet-1468	241	1	the	the	DET
admet-1468	241	2	results	result	NOUN
admet-1468	241	3	also	also	ADV
admet-1468	241	4	showed	show	VERB
admet-1468	241	5	that	that	SCONJ
admet-1468	241	6	the	the	DET
admet-1468	241	7	molecules	molecule	NOUN
admet-1468	241	8	could	could	AUX
admet-1468	241	9	not	not	PART
admet-1468	241	10	inhibit	inhibit	VERB
admet-1468	241	11	cyp2d6	cyp2d6	NOUN
admet-1468	241	12	,	,	PUNCT
admet-1468	241	13	while	while	SCONJ
admet-1468	241	14	all	all	DET
admet-1468	241	15	coumarin	coumarin	NOUN
admet-1468	241	16	-	-	PUNCT
admet-1468	241	17	quinone	quinone	NOUN
admet-1468	241	18	hybrids	hybrid	NOUN
admet-1468	241	19	are	be	AUX
admet-1468	241	20	good	good	ADJ
admet-1468	241	21	cyp3a4	cyp3a4	NOUN
admet-1468	241	22	enzyme	enzyme	NOUN
admet-1468	241	23	inhibitors	inhibitor	NOUN
admet-1468	241	24	.	.	PUNCT
admet-1468	242	1	this	this	DET
admet-1468	242	2	ability	ability	NOUN
admet-1468	242	3	of	of	ADP
admet-1468	242	4	the	the	DET
admet-1468	242	5	analogs	analog	NOUN
admet-1468	242	6	indicates	indicate	VERB
admet-1468	242	7	the	the	DET
admet-1468	242	8	ability	ability	NOUN
admet-1468	242	9	of	of	ADP
admet-1468	242	10	these	these	DET
admet-1468	242	11	compounds	compound	NOUN
admet-1468	242	12	on	on	ADP
admet-1468	242	13	the	the	DET
admet-1468	242	14	metabolism	metabolism	NOUN
admet-1468	242	15	of	of	ADP
admet-1468	242	16	xenobiotics	xenobiotics	PROPN
admet-1468	242	17	in	in	ADP
admet-1468	242	18	the	the	DET
admet-1468	242	19	body	body	NOUN
admet-1468	242	20	.	.	PUNCT
admet-1468	243	1	the	the	DET
admet-1468	243	2	total	total	ADJ
admet-1468	243	3	clearance	clearance	NOUN
admet-1468	243	4	of	of	ADP
admet-1468	243	5	dtbsa	dtbsa	NOUN
admet-1468	243	6	and	and	CCONJ
admet-1468	243	7	dtbsn	dtbsn	NOUN
admet-1468	243	8	is	be	AUX
admet-1468	243	9	high	high	ADJ
admet-1468	243	10	,	,	PUNCT
admet-1468	243	11	while	while	SCONJ
admet-1468	243	12	other	other	ADJ
admet-1468	243	13	analogs	analog	NOUN
admet-1468	243	14	wo	will	AUX
admet-1468	243	15	n’t	not	PART
admet-1468	243	16	be	be	AUX
admet-1468	243	17	eliminated	eliminate	VERB
admet-1468	243	18	from	from	ADP
admet-1468	243	19	the	the	DET
admet-1468	243	20	body	body	NOUN
admet-1468	243	21	.	.	PUNCT
admet-1468	244	1	all	all	DET
admet-1468	244	2	analogs	analog	NOUN
admet-1468	244	3	have	have	VERB
admet-1468	244	4	ld50	ld50	PROPN
admet-1468	244	5	values	value	NOUN
admet-1468	244	6	above	above	ADP
admet-1468	244	7	0.5	0.5	NUM
admet-1468	244	8	mm	mm	NOUN
admet-1468	244	9	and	and	CCONJ
admet-1468	244	10	,	,	PUNCT
admet-1468	244	11	thus	thus	ADV
admet-1468	244	12	,	,	PUNCT
admet-1468	244	13	they	they	PRON
admet-1468	244	14	are	be	AUX
admet-1468	244	15	non	non	ADJ
admet-1468	244	16	-	-	ADJ
admet-1468	244	17	toxic	toxic	ADJ
admet-1468	244	18	corroborating	corroborate	VERB
admet-1468	244	19	the	the	DET
admet-1468	244	20	in	in	X
admet-1468	244	21	vitro	vitro	X
admet-1468	244	22	results	result	NOUN
admet-1468	244	23	from	from	ADP
admet-1468	244	24	pbmcs	pbmcs	NOUN
admet-1468	244	25	.	.	PUNCT
admet-1468	245	1	the	the	DET
admet-1468	245	2	predicted	predict	VERB
admet-1468	245	3	results	result	NOUN
admet-1468	245	4	show	show	VERB
admet-1468	245	5	that	that	SCONJ
admet-1468	245	6	all	all	DET
admet-1468	245	7	analogs	analog	NOUN
admet-1468	245	8	may	may	AUX
admet-1468	245	9	cause	cause	VERB
admet-1468	245	10	hepatotoxicity	hepatotoxicity	NOUN
admet-1468	245	11	and	and	CCONJ
admet-1468	245	12	do	do	AUX
admet-1468	245	13	n’t	not	PART
admet-1468	245	14	have	have	VERB
admet-1468	245	15	skin	skin	NOUN
admet-1468	245	16	sensitization	sensitization	NOUN
admet-1468	245	17	potential	potential	NOUN
admet-1468	245	18	.	.	PUNCT
admet-1468	246	1	these	these	DET
admet-1468	246	2	overall	overall	ADJ
admet-1468	246	3	results	result	NOUN
admet-1468	246	4	of	of	ADP
admet-1468	246	5	the	the	DET
admet-1468	246	6	admet	admet	PROPN
admet-1468	246	7	studies	study	NOUN
admet-1468	246	8	disclosed	disclose	VERB
admet-1468	246	9	that	that	SCONJ
admet-1468	246	10	the	the	DET
admet-1468	246	11	compounds	compound	NOUN
admet-1468	246	12	have	have	VERB
admet-1468	246	13	good	good	ADJ
admet-1468	246	14	pharmacokinetic	pharmacokinetic	ADJ
admet-1468	246	15	properties	property	NOUN
admet-1468	246	16	.	.	PUNCT
admet-1468	247	1	the	the	DET
admet-1468	247	2	physicochemical	physicochemical	ADJ
admet-1468	247	3	properties	property	NOUN
admet-1468	247	4	of	of	ADP
admet-1468	247	5	the	the	DET
admet-1468	247	6	hybrid	hybrid	ADJ
admet-1468	247	7	compounds	compound	NOUN
admet-1468	247	8	were	be	AUX
admet-1468	247	9	predicted	predict	VERB
admet-1468	247	10	using	use	VERB
admet-1468	247	11	the	the	DET
admet-1468	247	12	swissadme	swissadme	NOUN
admet-1468	247	13	website	website	NOUN
admet-1468	247	14	.	.	PUNCT
admet-1468	248	1	the	the	DET
admet-1468	248	2	results	result	NOUN
admet-1468	248	3	are	be	AUX
admet-1468	248	4	presented	present	VERB
admet-1468	248	5	in	in	ADP
admet-1468	248	6	table	table	NOUN
admet-1468	248	7	5	5	NUM
admet-1468	248	8	.	.	PUNCT
admet-1468	249	1	the	the	DET
admet-1468	249	2	bioavailabilities	bioavailabilitie	NOUN
admet-1468	249	3	of	of	ADP
admet-1468	249	4	all	all	DET
admet-1468	249	5	analogs	analog	NOUN
admet-1468	249	6	are	be	AUX
admet-1468	249	7	within	within	ADP
admet-1468	249	8	the	the	DET
admet-1468	249	9	range	range	NOUN
admet-1468	249	10	(	(	PUNCT
admet-1468	249	11	0.1	0.1	NUM
admet-1468	249	12	to	to	PART
admet-1468	249	13	1	1	NUM
admet-1468	249	14	)	)	PUNCT
admet-1468	249	15	.	.	PUNCT
admet-1468	250	1	this	this	DET
admet-1468	250	2	profiling	profiling	NOUN
admet-1468	250	3	of	of	ADP
admet-1468	250	4	the	the	DET
admet-1468	250	5	compounds	compound	NOUN
admet-1468	250	6	brings	bring	VERB
admet-1468	250	7	out	out	ADP
admet-1468	250	8	promising	promise	VERB
admet-1468	250	9	observations	observation	NOUN
admet-1468	250	10	with	with	ADP
admet-1468	250	11	respect	respect	NOUN
admet-1468	250	12	to	to	ADP
admet-1468	250	13	their	their	PRON
admet-1468	250	14	pharmacological	pharmacological	ADJ
admet-1468	250	15	aspects	aspect	NOUN
admet-1468	250	16	.	.	PUNCT
admet-1468	251	1	the	the	DET
admet-1468	251	2	drug	drug	NOUN
admet-1468	251	3	-	-	PUNCT
admet-1468	251	4	likeness	likeness	NOUN
admet-1468	251	5	of	of	ADP
admet-1468	251	6	the	the	DET
admet-1468	251	7	test	test	NOUN
admet-1468	251	8	compounds	compound	NOUN
admet-1468	251	9	was	be	AUX
admet-1468	251	10	established	establish	VERB
admet-1468	251	11	based	base	VERB
admet-1468	251	12	on	on	ADP
admet-1468	251	13	their	their	PRON
admet-1468	251	14	physicochemical	physicochemical	ADJ
admet-1468	251	15	properties	property	NOUN
admet-1468	251	16	to	to	PART
admet-1468	251	17	find	find	VERB
admet-1468	251	18	oral	oral	ADJ
admet-1468	251	19	drug	drug	NOUN
admet-1468	251	20	candidates	candidate	NOUN
admet-1468	251	21	.	.	PUNCT
admet-1468	252	1	there	there	PRON
admet-1468	252	2	are	be	VERB
admet-1468	252	3	five	five	NUM
admet-1468	252	4	different	different	ADJ
admet-1468	252	5	rule	rule	NOUN
admet-1468	252	6	-	-	PUNCT
admet-1468	252	7	based	base	VERB
admet-1468	252	8	filters	filter	NOUN
admet-1468	252	9	[	[	X
admet-1468	252	10	41	41	NUM
admet-1468	252	11	]	]	PUNCT
admet-1468	252	12	that	that	PRON
admet-1468	252	13	are	be	AUX
admet-1468	252	14	in	in	ADP
admet-1468	252	15	practice	practice	NOUN
admet-1468	252	16	to	to	PART
admet-1468	252	17	determine	determine	VERB
admet-1468	252	18	the	the	DET
admet-1468	252	19	drug	drug	NOUN
admet-1468	252	20	-	-	PUNCT
admet-1468	252	21	likeness	likeness	NOUN
admet-1468	252	22	of	of	ADP
admet-1468	252	23	any	any	DET
admet-1468	252	24	compound	compound	NOUN
admet-1468	252	25	.	.	PUNCT
admet-1468	253	1	the	the	DET
admet-1468	253	2	results	result	NOUN
admet-1468	253	3	of	of	ADP
admet-1468	253	4	drug	drug	NOUN
admet-1468	253	5	-	-	PUNCT
admet-1468	253	6	likeness	likeness	NOUN
admet-1468	253	7	evaluation	evaluation	NOUN
admet-1468	253	8	of	of	ADP
admet-1468	253	9	the	the	DET
admet-1468	253	10	hybrid	hybrid	ADJ
admet-1468	253	11	compounds	compound	NOUN
admet-1468	253	12	are	be	AUX
admet-1468	253	13	shown	show	VERB
admet-1468	253	14	in	in	ADP
admet-1468	253	15	table	table	NOUN
admet-1468	253	16	6	6	NUM
admet-1468	253	17	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	253	18	a.	a.	NOUN
admet-1468	253	19	pangal	pangal	PROPN
admet-1468	253	20	and	and	CCONJ
admet-1468	253	21	k.	k.	PROPN
admet-1468	253	22	ahmed	ahmed	PROPN
admet-1468	253	23	admet	admet	PROPN
admet-1468	253	24	&	&	CCONJ
admet-1468	253	25	dmpk	dmpk	PROPN
admet-1468	253	26	11(1	11(1	NUM
admet-1468	253	27	)	)	PUNCT
admet-1468	253	28	(	(	PUNCT
admet-1468	253	29	2023	2023	NUM
admet-1468	253	30	)	)	PUNCT
admet-1468	253	31	81	81	NUM
admet-1468	253	32	-	-	SYM
admet-1468	253	33	96	96	NUM
admet-1468	253	34	92	92	NUM
admet-1468	253	35	table	table	NOUN
admet-1468	253	36	5	5	NUM
admet-1468	253	37	.	.	PUNCT
admet-1468	253	38	physicochemical	physicochemical	ADJ
admet-1468	253	39	properties	property	NOUN
admet-1468	253	40	of	of	ADP
admet-1468	253	41	the	the	DET
admet-1468	253	42	new	new	ADJ
admet-1468	253	43	coumarin	coumarin	NOUN
admet-1468	253	44	-	-	PUNCT
admet-1468	253	45	quinone	quinone	NOUN
admet-1468	253	46	hybrids	hybrid	NOUN
admet-1468	253	47	properties	property	NOUN
admet-1468	253	48	dtbsa	dtbsa	VERB
admet-1468	253	49	dtbsc	dtbsc	PROPN
admet-1468	253	50	dtbsb	dtbsb	PROPN
admet-1468	253	51	dtbsn	dtbsn	VERB
admet-1468	253	52	molecular	molecular	ADJ
admet-1468	253	53	weight	weight	NOUN
admet-1468	253	54	(	(	PUNCT
admet-1468	253	55	g	g	NOUN
admet-1468	253	56	/	/	SYM
admet-1468	253	57	mol	mol	NOUN
admet-1468	253	58	)	)	PUNCT
admet-1468	254	1	406.47	406.47	NUM
admet-1468	254	2	440.92	440.92	NUM
admet-1468	254	3	485.37	485.37	NUM
admet-1468	254	4	451.47	451.47	NUM
admet-1468	254	5	no	no	NOUN
admet-1468	254	6	.	.	PUNCT
admet-1468	254	7	of	of	ADP
admet-1468	254	8	heavy	heavy	ADJ
admet-1468	254	9	atoms	atom	NOUN
admet-1468	254	10	30	30	NUM
admet-1468	254	11	31	31	NUM
admet-1468	254	12	31	31	NUM
admet-1468	254	13	33	33	NUM
admet-1468	254	14	no	no	NOUN
admet-1468	254	15	.	.	PUNCT
admet-1468	255	1	of	of	ADP
admet-1468	255	2	arom	arom	PROPN
admet-1468	255	3	.	.	PUNCT
admet-1468	256	1	heavy	heavy	ADJ
admet-1468	256	2	atoms	atom	NOUN
admet-1468	256	3	10	10	NUM
admet-1468	256	4	10	10	NUM
admet-1468	256	5	10	10	NUM
admet-1468	256	6	10	10	NUM
admet-1468	256	7	no	no	NOUN
admet-1468	256	8	.	.	PUNCT
admet-1468	256	9	of	of	ADP
admet-1468	256	10	rotatable	rotatable	ADJ
admet-1468	256	11	bonds	bond	NOUN
admet-1468	256	12	5	5	NUM
admet-1468	256	13	5	5	NUM
admet-1468	256	14	5	5	NUM
admet-1468	256	15	6	6	NUM
admet-1468	256	16	no	no	NOUN
admet-1468	256	17	.	.	PUNCT
admet-1468	256	18	of	of	ADP
admet-1468	256	19	h	h	NOUN
admet-1468	256	20	-	-	PUNCT
admet-1468	256	21	bond	bond	NOUN
admet-1468	256	22	acceptors	acceptor	NOUN
admet-1468	256	23	5	5	NUM
admet-1468	256	24	5	5	NUM
admet-1468	256	25	5	5	NUM
admet-1468	256	26	7	7	NUM
admet-1468	256	27	no	no	NOUN
admet-1468	256	28	.	.	PUNCT
admet-1468	256	29	of	of	ADP
admet-1468	256	30	h	h	NOUN
admet-1468	256	31	-	-	PUNCT
admet-1468	256	32	bond	bond	NOUN
admet-1468	256	33	donors	donor	NOUN
admet-1468	256	34	1	1	NUM
admet-1468	256	35	1	1	NUM
admet-1468	256	36	1	1	NUM
admet-1468	256	37	1	1	NUM
admet-1468	256	38	molar	molar	ADJ
admet-1468	256	39	refractivity	refractivity	NOUN
admet-1468	256	40	118.27	118.27	NUM
admet-1468	256	41	123.28	123.28	NUM
admet-1468	256	42	125.97	125.97	NUM
admet-1468	256	43	127.10	127.10	NUM
admet-1468	256	44	total	total	ADJ
admet-1468	256	45	polar	polar	ADJ
admet-1468	256	46	surface	surface	NOUN
admet-1468	256	47	area	area	NOUN
admet-1468	256	48	å²	å²	PROPN
admet-1468	256	49	88.74	88.74	NUM
admet-1468	256	50	88.74	88.74	NUM
admet-1468	256	51	88.74	88.74	NUM
admet-1468	256	52	134.56	134.56	NUM
admet-1468	256	53	solubility	solubility	NOUN
admet-1468	256	54	log	log	NOUN
admet-1468	256	55	s	s	PART
admet-1468	256	56	(	(	PUNCT
admet-1468	256	57	esol	esol	PROPN
admet-1468	256	58	)	)	PUNCT
admet-1468	256	59	-5.80	-5.80	PROPN
admet-1468	256	60	-6.40	-6.40	PROPN
admet-1468	256	61	-6.71	-6.71	VERB
admet-1468	256	62	-5.88	-5.88	NUM
admet-1468	256	63	log	log	NOUN
admet-1468	256	64	s	s	PART
admet-1468	256	65	(	(	PUNCT
admet-1468	256	66	ali	ali	PROPN
admet-1468	256	67	)	)	PUNCT
admet-1468	256	68	-7.22	-7.22	NOUN
admet-1468	256	69	-7.87	-7.87	PROPN
admet-1468	256	70	-7.93	-7.93	NUM
admet-1468	256	71	-8.00	-8.00	PROPN
admet-1468	256	72	log	log	PROPN
admet-1468	256	73	s	s	PART
admet-1468	256	74	(	(	PUNCT
admet-1468	256	75	silicos	silico	NOUN
admet-1468	256	76	-	-	PUNCT
admet-1468	256	77	it	it	PRON
admet-1468	256	78	)	)	PUNCT
admet-1468	256	79	-7.04	-7.04	NUM
admet-1468	256	80	-7.62	-7.62	NUM
admet-1468	256	81	-7.81	-7.81	INTJ
admet-1468	256	82	-6.38	-6.38	PROPN
admet-1468	256	83	lipophilicity	lipophilicity	NOUN
admet-1468	256	84	mlogp	mlogp	NOUN
admet-1468	256	85	3.11	3.11	NUM
admet-1468	256	86	3.59	3.59	NUM
admet-1468	256	87	3.69	3.69	NUM
admet-1468	256	88	2.23	2.23	NUM
admet-1468	256	89	wlogp	wlogp	NOUN
admet-1468	256	90	4.41	4.41	NUM
admet-1468	256	91	5.06	5.06	NUM
admet-1468	256	92	5.17	5.17	NUM
admet-1468	256	93	4.31	4.31	NUM
admet-1468	256	94	xlogp3	xlogp3	X
admet-1468	256	95	5.59	5.59	NUM
admet-1468	256	96	6.22	6.22	NUM
admet-1468	256	97	6.28	6.28	NUM
admet-1468	256	98	5.42	5.42	NUM
admet-1468	256	99	.	.	PUNCT
admet-1468	257	1	table	table	NOUN
admet-1468	257	2	6	6	NUM
admet-1468	257	3	.	.	PUNCT
admet-1468	257	4	drug	drug	NOUN
admet-1468	257	5	likeness	likeness	NOUN
admet-1468	257	6	evaluation	evaluation	NOUN
admet-1468	257	7	of	of	ADP
admet-1468	257	8	the	the	DET
admet-1468	257	9	new	new	ADJ
admet-1468	257	10	coumarin	coumarin	NOUN
admet-1468	257	11	-	-	PUNCT
admet-1468	257	12	quinone	quinone	NOUN
admet-1468	257	13	hybrids	hybrid	NOUN
admet-1468	257	14	rule	rule	NOUN
admet-1468	257	15	-	-	PUNCT
admet-1468	257	16	based	base	VERB
admet-1468	257	17	filters	filter	NOUN
admet-1468	257	18	dtbsa	dtbsa	VERB
admet-1468	257	19	dtbsc	dtbsc	PROPN
admet-1468	257	20	dtbsb	dtbsb	PROPN
admet-1468	257	21	dtbsn	dtbsn	PROPN
admet-1468	257	22	lipinski	lipinski	PROPN
admet-1468	257	23	violations	violation	NOUN
admet-1468	257	24	0	0	NUM
admet-1468	257	25	0	0	NUM
admet-1468	257	26	0	0	NUM
admet-1468	257	27	0	0	NUM
admet-1468	257	28	ghose	ghose	PROPN
admet-1468	257	29	violations	violation	NOUN
admet-1468	257	30	0	0	NUM
admet-1468	257	31	0	0	NUM
admet-1468	257	32	0	0	NUM
admet-1468	257	33	0	0	NUM
admet-1468	257	34	veber	veber	NOUN
admet-1468	257	35	violations	violation	NOUN
admet-1468	257	36	0	0	NUM
admet-1468	257	37	0	0	NUM
admet-1468	257	38	0	0	SYM
admet-1468	257	39	0	0	NUM
admet-1468	257	40	egan	egan	ADJ
admet-1468	257	41	violations	violation	NOUN
admet-1468	257	42	0	0	NUM
admet-1468	257	43	0	0	NUM
admet-1468	257	44	0	0	NUM
admet-1468	257	45	1	1	NUM
admet-1468	257	46	(	(	PUNCT
admet-1468	257	47	tpsa	tpsa	NOUN
admet-1468	257	48	>	>	X
admet-1468	257	49	131.6	131.6	NUM
admet-1468	257	50	)	)	PUNCT
admet-1468	257	51	muegge	muegge	PROPN
admet-1468	257	52	violations	violation	NOUN
admet-1468	257	53	1	1	NUM
admet-1468	257	54	(	(	PUNCT
admet-1468	257	55	xlogp3	xlogp3	X
admet-1468	257	56	>	>	X
admet-1468	257	57	5	5	NUM
admet-1468	257	58	)	)	PUNCT
admet-1468	257	59	1	1	NUM
admet-1468	257	60	(	(	PUNCT
admet-1468	257	61	xlogp3	xlogp3	X
admet-1468	257	62	>	>	X
admet-1468	257	63	5	5	NUM
admet-1468	257	64	)	)	PUNCT
admet-1468	257	65	1	1	NUM
admet-1468	257	66	(	(	PUNCT
admet-1468	257	67	xlogp3	xlogp3	X
admet-1468	257	68	>	>	X
admet-1468	257	69	5	5	NUM
admet-1468	257	70	)	)	PUNCT
admet-1468	257	71	1	1	NUM
admet-1468	257	72	(	(	PUNCT
admet-1468	257	73	xlogp3	xlogp3	X
admet-1468	257	74	>	>	X
admet-1468	257	75	5	5	NUM
admet-1468	257	76	)	)	PUNCT
admet-1468	257	77	bioavailability	bioavailability	NOUN
admet-1468	257	78	score	score	NOUN
admet-1468	257	79	0.55	0.55	NUM
admet-1468	257	80	0.55	0.55	NUM
admet-1468	257	81	0.55	0.55	NUM
admet-1468	257	82	0.55	0.55	NUM
admet-1468	257	83	pains	pain	NOUN
admet-1468	257	84	no	no	INTJ
admet-1468	257	85	.	.	PUNCT
admet-1468	257	86	of	of	ADP
admet-1468	257	87	alerts	alert	NOUN
admet-1468	257	88	1	1	NUM
admet-1468	257	89	(	(	PUNCT
admet-1468	257	90	quinone	quinone	NOUN
admet-1468	257	91	)	)	PUNCT
admet-1468	257	92	1	1	NUM
admet-1468	257	93	(	(	PUNCT
admet-1468	257	94	quinone	quinone	NOUN
admet-1468	257	95	)	)	PUNCT
admet-1468	257	96	1	1	NUM
admet-1468	257	97	(	(	PUNCT
admet-1468	257	98	quinone	quinone	NOUN
admet-1468	257	99	)	)	PUNCT
admet-1468	257	100	1	1	NUM
admet-1468	257	101	(	(	PUNCT
admet-1468	257	102	quinone	quinone	NOUN
admet-1468	257	103	)	)	PUNCT
admet-1468	257	104	brenk	brenk	NOUN
admet-1468	257	105	no	no	INTJ
admet-1468	257	106	.	.	PUNCT
admet-1468	258	1	of	of	ADP
admet-1468	258	2	alerts	alert	NOUN
admet-1468	258	3	3	3	NUM
admet-1468	258	4	(	(	PUNCT
admet-1468	258	5	quinone	quinone	NOUN
admet-1468	258	6	,	,	PUNCT
admet-1468	258	7	coumarin	coumarin	NOUN
admet-1468	258	8	and	and	CCONJ
admet-1468	258	9	imine	imine	NOUN
admet-1468	258	10	)	)	PUNCT
admet-1468	258	11	3	3	NUM
admet-1468	258	12	(	(	PUNCT
admet-1468	258	13	quinone	quinone	NOUN
admet-1468	258	14	,	,	PUNCT
admet-1468	258	15	coumarin	coumarin	NOUN
admet-1468	258	16	and	and	CCONJ
admet-1468	258	17	imine	imine	NOUN
admet-1468	258	18	)	)	PUNCT
admet-1468	258	19	3	3	NUM
admet-1468	258	20	(	(	PUNCT
admet-1468	258	21	quinone	quinone	NOUN
admet-1468	258	22	,	,	PUNCT
admet-1468	258	23	coumarin	coumarin	NOUN
admet-1468	258	24	and	and	CCONJ
admet-1468	258	25	imine	imine	NOUN
admet-1468	258	26	)	)	PUNCT
admet-1468	258	27	5	5	NUM
admet-1468	258	28	(	(	PUNCT
admet-1468	258	29	quinone	quinone	NOUN
admet-1468	258	30	,	,	PUNCT
admet-1468	258	31	coumarin	coumarin	NOUN
admet-1468	258	32	,	,	PUNCT
admet-1468	258	33	imine	imine	NOUN
admet-1468	258	34	,	,	PUNCT
admet-1468	258	35	nitro	nitro	NOUN
admet-1468	258	36	group	group	NOUN
admet-1468	258	37	and	and	CCONJ
admet-1468	258	38	n	n	CCONJ
admet-1468	258	39	-	-	PUNCT
admet-1468	258	40	o	o	NOUN
admet-1468	258	41	bond	bond	NOUN
admet-1468	258	42	)	)	PUNCT
admet-1468	258	43	lead	lead	VERB
admet-1468	258	44	likeness	likeness	NOUN
admet-1468	258	45	no	no	INTJ
admet-1468	258	46	.	.	PUNCT
admet-1468	259	1	of	of	ADP
admet-1468	259	2	violations	violation	NOUN
admet-1468	259	3	2	2	NUM
admet-1468	259	4	(	(	PUNCT
admet-1468	259	5	mw>350	mw>350	PROPN
admet-1468	259	6	,	,	PUNCT
admet-1468	259	7	xlogp3>3.5	xlogp3>3.5	PROPN
admet-1468	259	8	)	)	PUNCT
admet-1468	259	9	2	2	NUM
admet-1468	259	10	(	(	PUNCT
admet-1468	259	11	mw>350	mw>350	PROPN
admet-1468	259	12	,	,	PUNCT
admet-1468	259	13	xlogp3>3.5	xlogp3>3.5	PROPN
admet-1468	259	14	)	)	PUNCT
admet-1468	259	15	2	2	NUM
admet-1468	259	16	(	(	PUNCT
admet-1468	259	17	mw>350	mw>350	PROPN
admet-1468	259	18	,	,	PUNCT
admet-1468	259	19	xlogp3>3.5	xlogp3>3.5	PROPN
admet-1468	259	20	)	)	PUNCT
admet-1468	259	21	2	2	NUM
admet-1468	259	22	(	(	PUNCT
admet-1468	259	23	mw>350	mw>350	PROPN
admet-1468	259	24	,	,	PUNCT
admet-1468	259	25	xlogp3>3.5	xlogp3>3.5	PROPN
admet-1468	259	26	)	)	PUNCT
admet-1468	259	27	the	the	DET
admet-1468	259	28	predictions	prediction	NOUN
admet-1468	259	29	revealed	reveal	VERB
admet-1468	259	30	that	that	SCONJ
admet-1468	259	31	all	all	DET
admet-1468	259	32	test	test	NOUN
admet-1468	259	33	compounds	compound	NOUN
admet-1468	259	34	have	have	VERB
admet-1468	259	35	good	good	ADJ
admet-1468	259	36	drug	drug	NOUN
admet-1468	259	37	similarity	similarity	NOUN
admet-1468	259	38	and	and	CCONJ
admet-1468	259	39	can	can	AUX
admet-1468	259	40	be	be	AUX
admet-1468	259	41	suitable	suitable	ADJ
admet-1468	259	42	drug	drug	NOUN
admet-1468	259	43	candidates	candidate	NOUN
admet-1468	259	44	for	for	ADP
admet-1468	259	45	further	further	ADJ
admet-1468	259	46	study	study	NOUN
admet-1468	259	47	.	.	PUNCT
admet-1468	260	1	they	they	PRON
admet-1468	260	2	have	have	VERB
admet-1468	260	3	no	no	DET
admet-1468	260	4	violation	violation	NOUN
admet-1468	260	5	of	of	ADP
admet-1468	260	6	drug	drug	NOUN
admet-1468	260	7	-	-	PUNCT
admet-1468	260	8	likeness	likeness	NOUN
admet-1468	260	9	according	accord	VERB
admet-1468	260	10	to	to	ADP
admet-1468	260	11	the	the	DET
admet-1468	260	12	criteria	criterion	NOUN
admet-1468	260	13	defined	define	VERB
admet-1468	260	14	by	by	ADP
admet-1468	260	15	lipinski	lipinski	PROPN
admet-1468	260	16	,	,	PUNCT
admet-1468	260	17	ghose	ghose	PROPN
admet-1468	260	18	and	and	CCONJ
admet-1468	260	19	veber	veber	PROPN
admet-1468	260	20	,	,	PUNCT
admet-1468	260	21	but	but	CCONJ
admet-1468	260	22	dtbsn	dtbsn	NOUN
admet-1468	260	23	exhibited	exhibit	VERB
admet-1468	260	24	one	one	NUM
admet-1468	260	25	violation	violation	NOUN
admet-1468	260	26	in	in	ADP
admet-1468	260	27	the	the	DET
admet-1468	260	28	egan	egan	PROPN
admet-1468	260	29	filter	filter	NOUN
admet-1468	260	30	due	due	ADP
admet-1468	260	31	to	to	ADP
admet-1468	260	32	a	a	DET
admet-1468	260	33	larger	large	ADJ
admet-1468	260	34	tpsa	tpsa	NOUN
admet-1468	260	35	value	value	NOUN
admet-1468	260	36	.	.	PUNCT
admet-1468	261	1	all	all	DET
admet-1468	261	2	analogs	analog	NOUN
admet-1468	261	3	showed	show	VERB
admet-1468	261	4	muegge	muegge	PROPN
admet-1468	261	5	’s	’s	PART
admet-1468	261	6	filter	filter	NOUN
admet-1468	261	7	violations	violation	NOUN
admet-1468	261	8	,	,	PUNCT
admet-1468	261	9	corresponding	correspond	VERB
admet-1468	261	10	to	to	ADP
admet-1468	261	11	xlogp3	xlogp3	PROPN
admet-1468	261	12	>	>	X
admet-1468	262	1	5	5	NUM
admet-1468	262	2	.	.	PUNCT
admet-1468	263	1	according	accord	VERB
admet-1468	263	2	to	to	ADP
admet-1468	263	3	the	the	DET
admet-1468	263	4	five	five	NUM
admet-1468	263	5	laws	law	NOUN
admet-1468	263	6	,	,	PUNCT
admet-1468	263	7	a	a	DET
admet-1468	263	8	molecule	molecule	NOUN
admet-1468	263	9	can	can	AUX
admet-1468	263	10	be	be	AUX
admet-1468	263	11	orally	orally	ADV
admet-1468	263	12	active	active	ADJ
admet-1468	263	13	/	/	SYM
admet-1468	263	14	absorbent	absorbent	NOUN
admet-1468	263	15	only	only	ADV
admet-1468	263	16	if	if	SCONJ
admet-1468	263	17	it	it	PRON
admet-1468	263	18	does	do	AUX
admet-1468	263	19	not	not	PART
admet-1468	263	20	violate	violate	VERB
admet-1468	263	21	two	two	NUM
admet-1468	263	22	or	or	CCONJ
admet-1468	263	23	more	more	ADJ
admet-1468	263	24	of	of	ADP
admet-1468	263	25	the	the	DET
admet-1468	263	26	above	above	ADJ
admet-1468	263	27	rules	rule	NOUN
admet-1468	263	28	[	[	X
admet-1468	263	29	42	42	NUM
admet-1468	263	30	]	]	PUNCT
admet-1468	263	31	.	.	PUNCT
admet-1468	264	1	all	all	DET
admet-1468	264	2	molecules	molecule	NOUN
admet-1468	264	3	resist	resist	VERB
admet-1468	264	4	brenk	brenk	NOUN
admet-1468	264	5	’s	’s	PART
admet-1468	264	6	rule	rule	NOUN
admet-1468	264	7	due	due	ADP
admet-1468	264	8	to	to	ADP
admet-1468	264	9	the	the	DET
admet-1468	264	10	coumarin	coumarin	NOUN
admet-1468	264	11	,	,	PUNCT
admet-1468	264	12	quinone	quinone	NOUN
admet-1468	264	13	and	and	CCONJ
admet-1468	264	14	imine	imine	NOUN
admet-1468	264	15	fragments	fragment	NOUN
admet-1468	264	16	.	.	PUNCT
admet-1468	265	1	all	all	DET
admet-1468	265	2	analogs	analog	NOUN
admet-1468	265	3	contain	contain	VERB
admet-1468	265	4	a	a	DET
admet-1468	265	5	quinone	quinone	NOUN
admet-1468	265	6	moiety	moiety	NOUN
admet-1468	265	7	,	,	PUNCT
admet-1468	265	8	which	which	PRON
admet-1468	265	9	is	be	AUX
admet-1468	265	10	responsible	responsible	ADJ
admet-1468	265	11	for	for	ADP
admet-1468	265	12	one	one	NUM
admet-1468	265	13	alert	alert	NOUN
admet-1468	265	14	in	in	ADP
admet-1468	265	15	pains	pain	NOUN
admet-1468	265	16	.	.	PUNCT
admet-1468	266	1	however	however	ADV
admet-1468	266	2	,	,	PUNCT
admet-1468	266	3	all	all	DET
admet-1468	266	4	compounds	compound	NOUN
admet-1468	266	5	showed	show	VERB
admet-1468	266	6	two	two	NUM
admet-1468	266	7	violations	violation	NOUN
admet-1468	266	8	in	in	ADP
admet-1468	266	9	lead	lead	ADJ
admet-1468	266	10	likeness	likeness	NOUN
admet-1468	266	11	due	due	ADP
admet-1468	266	12	to	to	ADP
admet-1468	266	13	large	large	ADJ
admet-1468	266	14	molecular	molecular	ADJ
admet-1468	266	15	weight	weight	NOUN
admet-1468	266	16	(	(	PUNCT
admet-1468	266	17	mw>350	mw>350	NUM
admet-1468	266	18	)	)	PUNCT
admet-1468	266	19	and	and	CCONJ
admet-1468	266	20	xlogp3	xlogp3	PROPN
admet-1468	266	21	values	value	NOUN
admet-1468	266	22	,	,	PUNCT
admet-1468	266	23	which	which	PRON
admet-1468	266	24	should	should	AUX
admet-1468	266	25	be	be	AUX
admet-1468	266	26	>	>	ADP
admet-1468	266	27	3.5	3.5	NUM
admet-1468	266	28	.	.	PUNCT
admet-1468	267	1	thus	thus	ADV
admet-1468	267	2	,	,	PUNCT
admet-1468	267	3	admet	admet	PROPN
admet-1468	267	4	&	&	CCONJ
admet-1468	267	5	dmpk	dmpk	PROPN
admet-1468	267	6	11(1	11(1	NUM
admet-1468	267	7	)	)	PUNCT
admet-1468	267	8	(	(	PUNCT
admet-1468	267	9	2023	2023	NUM
admet-1468	267	10	)	)	PUNCT
admet-1468	267	11	81	81	NUM
admet-1468	267	12	-	-	SYM
admet-1468	267	13	96	96	NUM
admet-1468	267	14	coumarin	coumarin	NOUN
admet-1468	267	15	-	-	PUNCT
admet-1468	267	16	quinone	quinone	NOUN
admet-1468	267	17	hybrids	hybrid	NOUN
admet-1468	267	18	doi	doi	NOUN
admet-1468	267	19	:	:	PUNCT
admet-1468	267	20	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	267	21	93	93	NUM
admet-1468	267	22	these	these	DET
admet-1468	267	23	preliminary	preliminary	ADJ
admet-1468	267	24	results	result	NOUN
admet-1468	267	25	provide	provide	VERB
admet-1468	267	26	the	the	DET
admet-1468	267	27	lead	lead	NOUN
admet-1468	267	28	for	for	ADP
admet-1468	267	29	the	the	DET
admet-1468	267	30	design	design	NOUN
admet-1468	267	31	of	of	ADP
admet-1468	267	32	more	more	ADV
admet-1468	267	33	potent	potent	ADJ
admet-1468	267	34	biologically	biologically	ADV
admet-1468	267	35	active	active	ADJ
admet-1468	267	36	drugs	drug	NOUN
admet-1468	267	37	with	with	ADP
admet-1468	267	38	fewer	few	ADJ
admet-1468	267	39	toxicities	toxicity	NOUN
admet-1468	267	40	.	.	PUNCT
admet-1468	268	1	conclusions	conclusion	NOUN
admet-1468	268	2	four	four	NUM
admet-1468	268	3	new	new	ADJ
admet-1468	268	4	coumarin	coumarin	NOUN
admet-1468	268	5	-	-	PUNCT
admet-1468	268	6	quinone	quinone	NOUN
admet-1468	268	7	hybrids	hybrid	NOUN
admet-1468	268	8	were	be	AUX
admet-1468	268	9	synthesized	synthesize	VERB
admet-1468	268	10	from	from	ADP
admet-1468	268	11	3	3	NUM
admet-1468	268	12	-	-	PUNCT
admet-1468	268	13	acetylcoumarin	acetylcoumarin	NOUN
admet-1468	268	14	and	and	CCONJ
admet-1468	268	15	2,6	2,6	NUM
admet-1468	268	16	-	-	NOUN
admet-1468	268	17	di	di	NOUN
admet-1468	268	18	-	-	PUNCT
admet-1468	268	19	tert	tert	NOUN
admet-1468	268	20	-	-	PUNCT
admet-1468	268	21	butyl-1,4benzoquinone	butyl-1,4benzoquinone	NOUN
admet-1468	268	22	and	and	CCONJ
admet-1468	268	23	tested	test	VERB
admet-1468	268	24	for	for	ADP
admet-1468	268	25	in	in	ADP
admet-1468	268	26	vitro	vitro	X
admet-1468	268	27	antimicrobial	antimicrobial	ADJ
admet-1468	268	28	,	,	PUNCT
admet-1468	268	29	antioxidant	antioxidant	ADJ
admet-1468	268	30	and	and	CCONJ
admet-1468	268	31	anticancer	anticancer	NOUN
admet-1468	268	32	activities	activity	NOUN
admet-1468	268	33	.	.	PUNCT
admet-1468	269	1	the	the	DET
admet-1468	269	2	results	result	NOUN
admet-1468	269	3	revealed	reveal	VERB
admet-1468	269	4	that	that	SCONJ
admet-1468	269	5	the	the	DET
admet-1468	269	6	analogs	analog	NOUN
admet-1468	269	7	dtbsb	dtbsb	NOUN
admet-1468	269	8	and	and	CCONJ
admet-1468	269	9	dtbsn	dtbsn	NOUN
admet-1468	269	10	were	be	AUX
admet-1468	269	11	the	the	DET
admet-1468	269	12	more	more	ADV
admet-1468	269	13	active	active	ADJ
admet-1468	269	14	antimicrobial	antimicrobial	ADJ
admet-1468	269	15	agents	agent	NOUN
admet-1468	269	16	when	when	SCONJ
admet-1468	269	17	compared	compare	VERB
admet-1468	269	18	to	to	ADP
admet-1468	269	19	the	the	DET
admet-1468	269	20	other	other	ADJ
admet-1468	269	21	analogs	analog	NOUN
admet-1468	269	22	.	.	PUNCT
admet-1468	270	1	dtbsn	dtbsn	NOUN
admet-1468	270	2	exhibited	exhibit	VERB
admet-1468	270	3	the	the	DET
admet-1468	270	4	best	good	ADJ
admet-1468	270	5	antioxidant	antioxidant	ADJ
admet-1468	270	6	activity	activity	NOUN
admet-1468	270	7	and	and	CCONJ
admet-1468	270	8	it	it	PRON
admet-1468	270	9	may	may	AUX
admet-1468	270	10	have	have	VERB
admet-1468	270	11	a	a	DET
admet-1468	270	12	higher	high	ADJ
admet-1468	270	13	therapeutic	therapeutic	ADJ
admet-1468	270	14	potential	potential	NOUN
admet-1468	270	15	as	as	ADP
admet-1468	270	16	a	a	DET
admet-1468	270	17	chemoprotective	chemoprotective	ADJ
admet-1468	270	18	agent	agent	NOUN
admet-1468	270	19	against	against	ADP
admet-1468	270	20	oxidative	oxidative	ADJ
admet-1468	270	21	stress	stress	NOUN
admet-1468	270	22	-	-	PUNCT
admet-1468	270	23	related	relate	VERB
admet-1468	270	24	degenerative	degenerative	ADJ
admet-1468	270	25	diseases	disease	NOUN
admet-1468	270	26	.	.	PUNCT
admet-1468	271	1	the	the	DET
admet-1468	271	2	toxicity	toxicity	NOUN
admet-1468	271	3	of	of	ADP
admet-1468	271	4	the	the	DET
admet-1468	271	5	synthesized	synthesize	VERB
admet-1468	271	6	hybrids	hybrid	NOUN
admet-1468	271	7	was	be	AUX
admet-1468	271	8	tested	test	VERB
admet-1468	271	9	on	on	ADP
admet-1468	271	10	human	human	ADJ
admet-1468	271	11	peripheral	peripheral	ADJ
admet-1468	271	12	mononuclear	mononuclear	ADJ
admet-1468	271	13	cells	cell	NOUN
admet-1468	271	14	(	(	PUNCT
admet-1468	271	15	pbmcs	pbmcs	NOUN
admet-1468	271	16	)	)	PUNCT
admet-1468	271	17	,	,	PUNCT
admet-1468	271	18	and	and	CCONJ
admet-1468	271	19	they	they	PRON
admet-1468	271	20	were	be	AUX
admet-1468	271	21	found	find	VERB
admet-1468	271	22	to	to	PART
admet-1468	271	23	be	be	AUX
admet-1468	271	24	non	non	ADJ
admet-1468	271	25	-	-	ADJ
admet-1468	271	26	toxic	toxic	ADJ
admet-1468	271	27	to	to	ADP
admet-1468	271	28	normal	normal	ADJ
admet-1468	271	29	cells	cell	NOUN
admet-1468	271	30	.	.	PUNCT
admet-1468	272	1	the	the	DET
admet-1468	272	2	hybrids	hybrid	NOUN
admet-1468	272	3	dtbsb	dtbsb	VERB
admet-1468	272	4	and	and	CCONJ
admet-1468	272	5	dtbsn	dtbsn	NOUN
admet-1468	272	6	exhibited	exhibit	VERB
admet-1468	272	7	good	good	ADJ
admet-1468	272	8	antiproliferative	antiproliferative	ADJ
admet-1468	272	9	potential	potential	NOUN
admet-1468	272	10	against	against	ADP
admet-1468	272	11	all	all	DET
admet-1468	272	12	types	type	NOUN
admet-1468	272	13	of	of	ADP
admet-1468	272	14	tested	test	VERB
admet-1468	272	15	cancer	cancer	NOUN
admet-1468	272	16	cell	cell	NOUN
admet-1468	272	17	lines	line	NOUN
admet-1468	272	18	.	.	PUNCT
admet-1468	273	1	compound	compound	NOUN
admet-1468	273	2	dtbsb	dtbsb	NOUN
admet-1468	273	3	was	be	AUX
admet-1468	273	4	more	more	ADV
admet-1468	273	5	active	active	ADJ
admet-1468	273	6	against	against	ADP
admet-1468	273	7	mcf-7	mcf-7	PUNCT
admet-1468	273	8	and	and	CCONJ
admet-1468	273	9	ht-29	ht-29	PUNCT
admet-1468	273	10	cells	cell	NOUN
admet-1468	273	11	with	with	ADP
admet-1468	273	12	remarkable	remarkable	ADJ
admet-1468	273	13	ic50	ic50	PROPN
admet-1468	273	14	values	value	NOUN
admet-1468	273	15	,	,	PUNCT
admet-1468	273	16	while	while	SCONJ
admet-1468	273	17	dtbsn	dtbsn	NOUN
admet-1468	273	18	exhibited	exhibit	VERB
admet-1468	273	19	its	its	PRON
admet-1468	273	20	best	good	ADJ
admet-1468	273	21	potential	potential	NOUN
admet-1468	273	22	against	against	ADP
admet-1468	273	23	mda	mda	PROPN
admet-1468	273	24	-	-	PUNCT
admet-1468	273	25	mb-231	mb-231	PROPN
admet-1468	273	26	,	,	PUNCT
admet-1468	273	27	colo-205	colo-205	NOUN
admet-1468	273	28	and	and	CCONJ
admet-1468	273	29	a-549	a-549	NOUN
admet-1468	273	30	cancer	cancer	NOUN
admet-1468	273	31	cells	cell	NOUN
admet-1468	273	32	.	.	PUNCT
admet-1468	274	1	the	the	DET
admet-1468	274	2	ic50	ic50	PROPN
admet-1468	274	3	values	value	NOUN
admet-1468	274	4	of	of	ADP
admet-1468	274	5	both	both	DET
admet-1468	274	6	analogs	analog	NOUN
admet-1468	274	7	are	be	AUX
admet-1468	274	8	in	in	ADP
admet-1468	274	9	the	the	DET
admet-1468	274	10	range	range	NOUN
admet-1468	274	11	of	of	ADP
admet-1468	274	12	50	50	NUM
admet-1468	274	13	to	to	PART
admet-1468	274	14	100	100	NUM
admet-1468	274	15	µm	µm	ADP
admet-1468	274	16	making	make	VERB
admet-1468	274	17	them	they	PRON
admet-1468	274	18	suitable	suitable	ADJ
admet-1468	274	19	for	for	ADP
admet-1468	274	20	further	further	ADJ
admet-1468	274	21	lead	lead	NOUN
admet-1468	274	22	development	development	NOUN
admet-1468	274	23	.	.	PUNCT
admet-1468	275	1	furthermore	furthermore	ADV
admet-1468	275	2	,	,	PUNCT
admet-1468	275	3	all	all	DET
admet-1468	275	4	derivatives	derivative	NOUN
admet-1468	275	5	showed	show	VERB
admet-1468	275	6	a	a	DET
admet-1468	275	7	considerable	considerable	ADJ
admet-1468	275	8	selectivity	selectivity	NOUN
admet-1468	275	9	index	index	NOUN
admet-1468	275	10	(	(	PUNCT
admet-1468	275	11	more	more	ADJ
admet-1468	275	12	than	than	ADP
admet-1468	275	13	2	2	NUM
admet-1468	275	14	)	)	PUNCT
admet-1468	275	15	,	,	PUNCT
admet-1468	275	16	and	and	CCONJ
admet-1468	275	17	the	the	DET
admet-1468	275	18	selectivity	selectivity	NOUN
admet-1468	275	19	indexes	index	NOUN
admet-1468	275	20	entail	entail	VERB
admet-1468	275	21	that	that	SCONJ
admet-1468	275	22	the	the	DET
admet-1468	275	23	synthesized	synthesize	VERB
admet-1468	275	24	compounds	compound	NOUN
admet-1468	275	25	were	be	AUX
admet-1468	275	26	more	more	ADV
admet-1468	275	27	selective	selective	ADJ
admet-1468	275	28	toward	toward	ADP
admet-1468	275	29	cancer	cancer	NOUN
admet-1468	275	30	cells	cell	NOUN
admet-1468	275	31	than	than	ADP
admet-1468	275	32	the	the	DET
admet-1468	275	33	non	non	ADJ
admet-1468	275	34	-	-	ADJ
admet-1468	275	35	malignant	malignant	ADJ
admet-1468	275	36	cells	cell	NOUN
admet-1468	275	37	.	.	PUNCT
admet-1468	276	1	it	it	PRON
admet-1468	276	2	is	be	AUX
admet-1468	276	3	appropriate	appropriate	ADJ
admet-1468	276	4	to	to	PART
admet-1468	276	5	mention	mention	VERB
admet-1468	276	6	that	that	SCONJ
admet-1468	276	7	antibiotics	antibiotic	NOUN
admet-1468	276	8	interfere	interfere	VERB
admet-1468	276	9	with	with	ADP
admet-1468	276	10	the	the	DET
admet-1468	276	11	normal	normal	ADJ
admet-1468	276	12	functioning	functioning	NOUN
admet-1468	276	13	of	of	ADP
admet-1468	276	14	living	living	NOUN
admet-1468	276	15	cells	cell	NOUN
admet-1468	276	16	[	[	X
admet-1468	276	17	43	43	NUM
admet-1468	276	18	]	]	PUNCT
admet-1468	276	19	.	.	PUNCT
admet-1468	277	1	this	this	DET
admet-1468	277	2	property	property	NOUN
admet-1468	277	3	is	be	AUX
admet-1468	277	4	useful	useful	ADJ
admet-1468	277	5	for	for	ADP
admet-1468	277	6	controlling	control	VERB
admet-1468	277	7	the	the	DET
admet-1468	277	8	growth	growth	NOUN
admet-1468	277	9	of	of	ADP
admet-1468	277	10	microorganisms	microorganism	NOUN
admet-1468	277	11	,	,	PUNCT
admet-1468	277	12	but	but	CCONJ
admet-1468	277	13	at	at	ADP
admet-1468	277	14	the	the	DET
admet-1468	277	15	same	same	ADJ
admet-1468	277	16	time	time	NOUN
admet-1468	277	17	,	,	PUNCT
admet-1468	277	18	it	it	PRON
admet-1468	277	19	can	can	AUX
admet-1468	277	20	act	act	VERB
admet-1468	277	21	as	as	ADP
admet-1468	277	22	a	a	DET
admet-1468	277	23	double	double	ADJ
admet-1468	277	24	-	-	PUNCT
admet-1468	277	25	edged	edge	VERB
admet-1468	277	26	sword	sword	NOUN
admet-1468	277	27	and	and	CCONJ
admet-1468	277	28	can	can	AUX
admet-1468	277	29	also	also	ADV
admet-1468	277	30	interfere	interfere	VERB
admet-1468	277	31	with	with	ADP
admet-1468	277	32	the	the	DET
admet-1468	277	33	functioning	functioning	NOUN
admet-1468	277	34	of	of	ADP
admet-1468	277	35	metabolically	metabolically	ADV
admet-1468	277	36	active	active	ADJ
admet-1468	277	37	,	,	PUNCT
admet-1468	277	38	rapidly	rapidly	ADV
admet-1468	277	39	multiplying	multiply	VERB
admet-1468	277	40	cancer	cancer	NOUN
admet-1468	277	41	cells	cell	NOUN
admet-1468	277	42	[	[	X
admet-1468	277	43	44	44	NUM
admet-1468	277	44	]	]	PUNCT
admet-1468	277	45	.	.	PUNCT
admet-1468	278	1	the	the	DET
admet-1468	278	2	compounds	compound	NOUN
admet-1468	278	3	in	in	ADP
admet-1468	278	4	the	the	DET
admet-1468	278	5	present	present	ADJ
admet-1468	278	6	work	work	NOUN
admet-1468	278	7	have	have	AUX
admet-1468	278	8	shown	show	VERB
admet-1468	278	9	activity	activity	NOUN
admet-1468	278	10	against	against	ADP
admet-1468	278	11	the	the	DET
admet-1468	278	12	cancer	cancer	NOUN
admet-1468	278	13	cell	cell	NOUN
admet-1468	278	14	lines	line	NOUN
admet-1468	278	15	as	as	ADV
admet-1468	278	16	well	well	ADV
admet-1468	278	17	as	as	ADP
admet-1468	278	18	against	against	ADP
admet-1468	278	19	microorganisms	microorganism	NOUN
admet-1468	278	20	.	.	PUNCT
admet-1468	279	1	the	the	DET
admet-1468	279	2	observed	observe	VERB
admet-1468	279	3	antioxidant	antioxidant	ADJ
admet-1468	279	4	property	property	NOUN
admet-1468	279	5	of	of	ADP
admet-1468	279	6	these	these	DET
admet-1468	279	7	compounds	compound	NOUN
admet-1468	279	8	enables	enable	VERB
admet-1468	279	9	them	they	PRON
admet-1468	279	10	to	to	PART
admet-1468	279	11	reduce	reduce	VERB
admet-1468	279	12	oxidative	oxidative	ADJ
admet-1468	279	13	stress	stress	NOUN
admet-1468	279	14	,	,	PUNCT
admet-1468	279	15	play	play	VERB
admet-1468	279	16	chemoprotective	chemoprotective	ADJ
admet-1468	279	17	agents	agent	NOUN
admet-1468	279	18	'	'	PART
admet-1468	279	19	role	role	NOUN
admet-1468	279	20	in	in	ADP
admet-1468	279	21	the	the	DET
admet-1468	279	22	biological	biological	ADJ
admet-1468	279	23	system	system	NOUN
admet-1468	279	24	,	,	PUNCT
admet-1468	279	25	and	and	CCONJ
admet-1468	279	26	protect	protect	VERB
admet-1468	279	27	cells	cell	NOUN
admet-1468	279	28	from	from	ADP
admet-1468	279	29	oxidative	oxidative	ADJ
admet-1468	279	30	stress	stress	NOUN
admet-1468	279	31	-	-	PUNCT
admet-1468	279	32	induced	induce	VERB
admet-1468	279	33	neoplastic	neoplastic	ADJ
admet-1468	279	34	changes	change	NOUN
admet-1468	279	35	.	.	PUNCT
admet-1468	280	1	the	the	DET
admet-1468	280	2	in	in	ADP
admet-1468	280	3	vitro	vitro	X
admet-1468	280	4	results	result	NOUN
admet-1468	280	5	appear	appear	VERB
admet-1468	280	6	to	to	PART
admet-1468	280	7	be	be	AUX
admet-1468	280	8	in	in	ADP
admet-1468	280	9	agreement	agreement	NOUN
admet-1468	280	10	with	with	ADP
admet-1468	280	11	the	the	DET
admet-1468	280	12	observations	observation	NOUN
admet-1468	280	13	of	of	ADP
admet-1468	280	14	the	the	DET
admet-1468	280	15	molecular	molecular	ADJ
admet-1468	280	16	docking	docking	NOUN
admet-1468	280	17	study	study	NOUN
admet-1468	280	18	.	.	PUNCT
admet-1468	281	1	the	the	DET
admet-1468	281	2	pharmacokinetics	pharmacokinetic	NOUN
admet-1468	281	3	and	and	CCONJ
admet-1468	281	4	drug	drug	NOUN
admet-1468	281	5	-	-	PUNCT
admet-1468	281	6	likeness	likeness	NOUN
admet-1468	281	7	evaluation	evaluation	NOUN
admet-1468	281	8	showed	show	VERB
admet-1468	281	9	a	a	DET
admet-1468	281	10	high	high	ADJ
admet-1468	281	11	level	level	NOUN
admet-1468	281	12	of	of	ADP
admet-1468	281	13	gi	gi	NOUN
admet-1468	281	14	absorption	absorption	NOUN
admet-1468	281	15	of	of	ADP
admet-1468	281	16	up	up	ADP
admet-1468	281	17	to	to	PART
admet-1468	281	18	94	94	NUM
admet-1468	281	19	%	%	NOUN
admet-1468	281	20	,	,	PUNCT
admet-1468	281	21	while	while	SCONJ
admet-1468	281	22	all	all	DET
admet-1468	281	23	analogs	analog	NOUN
admet-1468	281	24	have	have	VERB
admet-1468	281	25	good	good	ADJ
admet-1468	281	26	solubility	solubility	NOUN
admet-1468	281	27	in	in	ADP
admet-1468	281	28	water	water	NOUN
admet-1468	281	29	.	.	PUNCT
admet-1468	282	1	the	the	DET
admet-1468	282	2	vdss	vdss	ADJ
admet-1468	282	3	,	,	PUNCT
admet-1468	282	4	bbb	bbb	ADJ
admet-1468	282	5	membrane	membrane	NOUN
admet-1468	282	6	permeability	permeability	NOUN
admet-1468	282	7	(	(	PUNCT
admet-1468	282	8	log	log	NOUN
admet-1468	282	9	bb	bb	NUM
admet-1468	282	10	)	)	PUNCT
admet-1468	282	11	and	and	CCONJ
admet-1468	282	12	cns	cns	PROPN
admet-1468	282	13	permeability	permeability	NOUN
admet-1468	282	14	were	be	AUX
admet-1468	282	15	used	use	VERB
admet-1468	282	16	to	to	PART
admet-1468	282	17	characterize	characterize	VERB
admet-1468	282	18	the	the	DET
admet-1468	282	19	distribution	distribution	NOUN
admet-1468	282	20	of	of	ADP
admet-1468	282	21	the	the	DET
admet-1468	282	22	new	new	ADJ
admet-1468	282	23	compounds	compound	NOUN
admet-1468	282	24	and	and	CCONJ
admet-1468	282	25	all	all	DET
admet-1468	282	26	analogs	analog	NOUN
admet-1468	282	27	have	have	VERB
admet-1468	282	28	a	a	DET
admet-1468	282	29	fair	fair	ADJ
admet-1468	282	30	distribution	distribution	NOUN
admet-1468	282	31	in	in	ADP
admet-1468	282	32	the	the	DET
admet-1468	282	33	body	body	NOUN
admet-1468	282	34	.	.	PUNCT
admet-1468	283	1	all	all	DET
admet-1468	283	2	analogs	analog	NOUN
admet-1468	283	3	did	do	AUX
admet-1468	283	4	not	not	PART
admet-1468	283	5	inhibit	inhibit	VERB
admet-1468	283	6	cyp2d6	cyp2d6	NOUN
admet-1468	283	7	and	and	CCONJ
admet-1468	283	8	but	but	CCONJ
admet-1468	283	9	they	they	PRON
admet-1468	283	10	were	be	AUX
admet-1468	283	11	good	good	ADJ
admet-1468	283	12	cyp3a4	cyp3a4	NOUN
admet-1468	283	13	inhibitors	inhibitor	NOUN
admet-1468	283	14	depicting	depict	VERB
admet-1468	283	15	the	the	DET
admet-1468	283	16	ability	ability	NOUN
admet-1468	283	17	of	of	ADP
admet-1468	283	18	these	these	DET
admet-1468	283	19	analogs	analog	NOUN
admet-1468	283	20	to	to	PART
admet-1468	283	21	metabolize	metabolize	VERB
admet-1468	283	22	xenobiotics	xenobiotic	NOUN
admet-1468	283	23	in	in	ADP
admet-1468	283	24	the	the	DET
admet-1468	283	25	body	body	NOUN
admet-1468	283	26	.	.	PUNCT
admet-1468	284	1	the	the	DET
admet-1468	284	2	predictions	prediction	NOUN
admet-1468	284	3	also	also	ADV
admet-1468	284	4	underlined	underline	VERB
admet-1468	284	5	the	the	DET
admet-1468	284	6	non	non	ADJ
admet-1468	284	7	-	-	ADJ
admet-1468	284	8	toxic	toxic	ADJ
admet-1468	284	9	nature	nature	NOUN
admet-1468	284	10	of	of	ADP
admet-1468	284	11	these	these	DET
admet-1468	284	12	analogs	analog	NOUN
admet-1468	284	13	,	,	PUNCT
admet-1468	284	14	which	which	PRON
admet-1468	284	15	is	be	AUX
admet-1468	284	16	reflected	reflect	VERB
admet-1468	284	17	through	through	ADP
admet-1468	284	18	high	high	ADJ
admet-1468	284	19	values	value	NOUN
admet-1468	284	20	of	of	ADP
admet-1468	284	21	total	total	ADJ
admet-1468	284	22	clearance	clearance	NOUN
admet-1468	284	23	,	,	PUNCT
admet-1468	284	24	non	non	ADJ
admet-1468	284	25	-	-	ADJ
admet-1468	284	26	hepatotoxic	hepatotoxic	ADJ
admet-1468	284	27	nature	nature	NOUN
admet-1468	284	28	and	and	CCONJ
admet-1468	284	29	no	no	DET
admet-1468	284	30	skin	skin	NOUN
admet-1468	284	31	sensitization	sensitization	NOUN
admet-1468	284	32	.	.	PUNCT
admet-1468	285	1	these	these	DET
admet-1468	285	2	results	result	NOUN
admet-1468	285	3	of	of	ADP
admet-1468	285	4	admet	admet	PROPN
admet-1468	285	5	studies	study	NOUN
admet-1468	285	6	revealed	reveal	VERB
admet-1468	285	7	that	that	SCONJ
admet-1468	285	8	the	the	DET
admet-1468	285	9	compounds	compound	NOUN
admet-1468	285	10	have	have	VERB
admet-1468	285	11	acceptable	acceptable	ADJ
admet-1468	285	12	admet	admet	NOUN
admet-1468	285	13	and	and	CCONJ
admet-1468	285	14	pharmacokinetic	pharmacokinetic	ADJ
admet-1468	285	15	properties	property	NOUN
admet-1468	285	16	.	.	PUNCT
admet-1468	286	1	furthermore	furthermore	ADV
admet-1468	286	2	,	,	PUNCT
admet-1468	286	3	the	the	DET
admet-1468	286	4	drug	drug	NOUN
admet-1468	286	5	-	-	PUNCT
admet-1468	286	6	likeness	likeness	NOUN
admet-1468	286	7	study	study	NOUN
admet-1468	286	8	revealed	reveal	VERB
admet-1468	286	9	that	that	SCONJ
admet-1468	286	10	most	most	ADJ
admet-1468	286	11	of	of	ADP
admet-1468	286	12	the	the	DET
admet-1468	286	13	compounds	compound	NOUN
admet-1468	286	14	fulfilled	fulfil	VERB
admet-1468	286	15	all	all	DET
admet-1468	286	16	requirements	requirement	NOUN
admet-1468	286	17	of	of	ADP
admet-1468	286	18	lipinski	lipinski	PROPN
admet-1468	286	19	,	,	PUNCT
admet-1468	286	20	ghose	ghose	PROPN
admet-1468	286	21	and	and	CCONJ
admet-1468	286	22	veber	veber	PROPN
admet-1468	286	23	rules	rule	NOUN
admet-1468	286	24	,	,	PUNCT
admet-1468	286	25	only	only	ADV
admet-1468	286	26	dtbsn	dtbsn	NOUN
admet-1468	286	27	exhibited	exhibit	VERB
admet-1468	286	28	one	one	NUM
admet-1468	286	29	violation	violation	NOUN
admet-1468	286	30	in	in	ADP
admet-1468	286	31	the	the	DET
admet-1468	286	32	egan	egan	PROPN
admet-1468	286	33	filter	filter	NOUN
admet-1468	286	34	due	due	ADP
admet-1468	286	35	to	to	ADP
admet-1468	286	36	a	a	DET
admet-1468	286	37	larger	large	ADJ
admet-1468	286	38	tpsa	tpsa	NOUN
admet-1468	286	39	value	value	NOUN
admet-1468	286	40	.	.	PUNCT
admet-1468	287	1	all	all	DET
admet-1468	287	2	analogs	analog	NOUN
admet-1468	287	3	showed	show	VERB
admet-1468	287	4	muegge	muegge	PROPN
admet-1468	287	5	’s	’s	PART
admet-1468	287	6	filter	filter	NOUN
admet-1468	287	7	violations	violation	NOUN
admet-1468	287	8	.	.	PUNCT
admet-1468	288	1	the	the	DET
admet-1468	288	2	compounds	compound	NOUN
admet-1468	288	3	possess	possess	VERB
admet-1468	288	4	a	a	DET
admet-1468	288	5	quinone	quinone	NOUN
admet-1468	288	6	moiety	moiety	NOUN
admet-1468	288	7	leading	lead	VERB
admet-1468	288	8	to	to	ADP
admet-1468	288	9	one	one	NUM
admet-1468	288	10	alert	alert	NOUN
admet-1468	288	11	in	in	ADP
admet-1468	288	12	pains	pain	NOUN
admet-1468	288	13	.	.	PUNCT
admet-1468	289	1	further	far	ADV
admet-1468	289	2	in	in	ADP
admet-1468	289	3	vitro	vitro	X
admet-1468	289	4	and	and	CCONJ
admet-1468	289	5	in	in	ADP
admet-1468	289	6	vivo	vivo	ADJ
admet-1468	289	7	studies	study	NOUN
admet-1468	289	8	will	will	AUX
admet-1468	289	9	be	be	AUX
admet-1468	289	10	necessary	necessary	ADJ
admet-1468	289	11	for	for	ADP
admet-1468	289	12	the	the	DET
admet-1468	289	13	confirmation	confirmation	NOUN
admet-1468	289	14	of	of	ADP
admet-1468	289	15	the	the	DET
admet-1468	289	16	chemoinformatics	chemoinformatic	NOUN
admet-1468	289	17	investigation	investigation	NOUN
admet-1468	289	18	.	.	PUNCT
admet-1468	290	1	these	these	DET
admet-1468	290	2	preliminary	preliminary	ADJ
admet-1468	290	3	results	result	NOUN
admet-1468	290	4	may	may	AUX
admet-1468	290	5	help	help	VERB
admet-1468	290	6	get	get	VERB
admet-1468	290	7	a	a	DET
admet-1468	290	8	lead	lead	ADJ
admet-1468	290	9	structure	structure	NOUN
admet-1468	290	10	with	with	ADP
admet-1468	290	11	selective	selective	ADJ
admet-1468	290	12	anticancer	anticancer	NOUN
admet-1468	290	13	potential	potential	NOUN
admet-1468	290	14	.	.	PUNCT
admet-1468	291	1	acknowledgements	acknowledgement	NOUN
admet-1468	291	2	:	:	PUNCT
admet-1468	291	3	we	we	PRON
admet-1468	291	4	are	be	AUX
admet-1468	291	5	thankful	thankful	ADJ
admet-1468	291	6	to	to	ADP
admet-1468	291	7	the	the	DET
admet-1468	291	8	department	department	NOUN
admet-1468	291	9	of	of	ADP
admet-1468	291	10	science	science	NOUN
admet-1468	291	11	and	and	CCONJ
admet-1468	291	12	technology	technology	NOUN
admet-1468	291	13	,	,	PUNCT
admet-1468	291	14	govt	govt	PROPN
admet-1468	291	15	.	.	PUNCT
admet-1468	292	1	of	of	ADP
admet-1468	292	2	india	india	PROPN
admet-1468	292	3	for	for	ADP
admet-1468	292	4	providing	provide	VERB
admet-1468	292	5	financial	financial	ADJ
admet-1468	292	6	assistance	assistance	NOUN
admet-1468	292	7	under	under	ADP
admet-1468	292	8	dst	dst	NOUN
admet-1468	292	9	-	-	PUNCT
admet-1468	292	10	fist	fist	NOUN
admet-1468	292	11	(	(	PUNCT
admet-1468	292	12	0	0	NUM
admet-1468	292	13	level	level	NOUN
admet-1468	292	14	)	)	PUNCT
admet-1468	292	15	to	to	PART
admet-1468	292	16	abeda	abeda	VERB
admet-1468	292	17	inamdar	inamdar	PROPN
admet-1468	292	18	senior	senior	ADJ
admet-1468	292	19	college	college	NOUN
admet-1468	292	20	,	,	PUNCT
admet-1468	292	21	pune	pune	NOUN
admet-1468	292	22	vide	vide	NOUN
admet-1468	292	23	letter	letter	NOUN
admet-1468	292	24	number	number	PROPN
admet-1468	292	25	sr	sr	PROPN
admet-1468	292	26	/	/	SYM
admet-1468	292	27	fst	fst	PROPN
admet-1468	292	28	/	/	SYM
admet-1468	292	29	college-277/2018	college-277/2018	NOUN
admet-1468	292	30	dated	date	VERB
admet-1468	292	31	20th	20th	ADJ
admet-1468	292	32	december	december	PROPN
admet-1468	292	33	2018	2018	NUM
admet-1468	292	34	.	.	PUNCT
admet-1468	293	1	we	we	PRON
admet-1468	293	2	are	be	AUX
admet-1468	293	3	grateful	grateful	ADJ
admet-1468	293	4	to	to	ADP
admet-1468	293	5	dr	dr	PROPN
admet-1468	293	6	.	.	PUNCT
admet-1468	293	7	p.	p.	NOUN
admet-1468	293	8	a.	a.	NOUN
admet-1468	293	9	inamdar	inamdar	PROPN
admet-1468	293	10	,	,	PUNCT
admet-1468	293	11	the	the	DET
admet-1468	293	12	president	president	NOUN
admet-1468	293	13	of	of	ADP
admet-1468	293	14	mce	mce	PROPN
admet-1468	293	15	society	society	PROPN
admet-1468	293	16	,	,	PUNCT
admet-1468	293	17	pune	pune	NOUN
admet-1468	293	18	for	for	ADP
admet-1468	293	19	providing	provide	VERB
admet-1468	293	20	the	the	DET
admet-1468	293	21	lab	lab	NOUN
admet-1468	293	22	facilities	facility	NOUN
admet-1468	293	23	.	.	PUNCT
admet-1468	294	1	we	we	PRON
admet-1468	294	2	are	be	AUX
admet-1468	294	3	also	also	ADV
admet-1468	294	4	thankful	thankful	ADJ
admet-1468	294	5	to	to	ADP
admet-1468	294	6	anti	anti	ADJ
admet-1468	294	7	-	-	ADJ
admet-1468	294	8	cancer	cancer	ADJ
admet-1468	294	9	drug	drug	NOUN
admet-1468	294	10	screening	screening	NOUN
admet-1468	294	11	facility	facility	NOUN
admet-1468	294	12	(	(	PUNCT
admet-1468	294	13	acdsf	acdsf	NOUN
admet-1468	294	14	)	)	PUNCT
admet-1468	294	15	at	at	ADP
admet-1468	294	16	actrec	actrec	NOUN
admet-1468	294	17	,	,	PUNCT
admet-1468	294	18	tata	tata	NOUN
admet-1468	294	19	memorial	memorial	ADJ
admet-1468	294	20	centre	centre	NOUN
admet-1468	294	21	,	,	PUNCT
admet-1468	294	22	navi	navi	PROPN
admet-1468	294	23	mumbai	mumbai	PROPN
admet-1468	294	24	.	.	PUNCT
admet-1468	295	1	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	295	2	a.	a.	NOUN
admet-1468	295	3	pangal	pangal	PROPN
admet-1468	295	4	and	and	CCONJ
admet-1468	295	5	k.	k.	PROPN
admet-1468	295	6	ahmed	ahmed	PROPN
admet-1468	295	7	admet	admet	PROPN
admet-1468	295	8	&	&	CCONJ
admet-1468	295	9	dmpk	dmpk	PROPN
admet-1468	295	10	11(1	11(1	NUM
admet-1468	295	11	)	)	PUNCT
admet-1468	295	12	(	(	PUNCT
admet-1468	295	13	2023	2023	NUM
admet-1468	295	14	)	)	PUNCT
admet-1468	295	15	81	81	NUM
admet-1468	295	16	-	-	SYM
admet-1468	295	17	96	96	NUM
admet-1468	295	18	94	94	NUM
admet-1468	295	19	conflict	conflict	NOUN
admet-1468	295	20	of	of	ADP
admet-1468	295	21	interest	interest	NOUN
admet-1468	295	22	:	:	PUNCT
admet-1468	295	23	the	the	DET
admet-1468	295	24	conflict	conflict	NOUN
admet-1468	295	25	of	of	ADP
admet-1468	295	26	interest	interest	NOUN
admet-1468	295	27	does	do	AUX
admet-1468	295	28	not	not	PART
admet-1468	295	29	exist	exist	VERB
admet-1468	295	30	.	.	PUNCT
admet-1468	296	1	references	reference	NOUN
admet-1468	296	2	[	[	X
admet-1468	296	3	1	1	NUM
admet-1468	296	4	]	]	X
admet-1468	296	5	z.m	z.m	PROPN
admet-1468	296	6	.	.	PROPN
admet-1468	296	7	nofal	nofal	PROPN
admet-1468	296	8	,	,	PUNCT
admet-1468	296	9	m.	m.	PROPN
admet-1468	296	10	i.	i.	PROPN
admet-1468	296	11	el	el	PROPN
admet-1468	296	12	-	-	PUNCT
admet-1468	296	13	zahar	zahar	PROPN
admet-1468	296	14	,	,	PUNCT
admet-1468	296	15	s.s	s.s	PROPN
admet-1468	296	16	.	.	PROPN
admet-1468	296	17	abd	abd	PROPN
admet-1468	297	1	el	el	PROPN
admet-1468	297	2	-	-	PROPN
admet-1468	297	3	karim	karim	PROPN
admet-1468	297	4	.	.	PUNCT
admet-1468	298	1	novel	novel	ADJ
admet-1468	298	2	coumarin	coumarin	NOUN
admet-1468	298	3	derivatives	derivative	NOUN
admet-1468	298	4	with	with	ADP
admet-1468	298	5	expected	expect	VERB
admet-1468	298	6	biological	biological	ADJ
admet-1468	298	7	activity	activity	NOUN
admet-1468	298	8	.	.	PUNCT
admet-1468	299	1	molecules	molecule	NOUN
admet-1468	299	2	5(2	5(2	NUM
admet-1468	299	3	)	)	PUNCT
admet-1468	299	4	(	(	PUNCT
admet-1468	299	5	2000	2000	NUM
admet-1468	299	6	)	)	PUNCT
admet-1468	299	7	99	99	NUM
admet-1468	299	8	-	-	SYM
admet-1468	299	9	113	113	NUM
admet-1468	299	10	.	.	PUNCT
admet-1468	300	1	https://doi.org/10.3390/50200099	https://doi.org/10.3390/50200099	VERB
admet-1468	300	2	.	.	PUNCT
admet-1468	301	1	[	[	X
admet-1468	301	2	2	2	NUM
admet-1468	301	3	]	]	PUNCT
admet-1468	301	4	a.	a.	NOUN
admet-1468	301	5	pangal	pangal	PROPN
admet-1468	301	6	,	,	PUNCT
admet-1468	301	7	y.	y.	PROPN
admet-1468	301	8	mujahid	mujahid	PROPN
admet-1468	301	9	,	,	PUNCT
admet-1468	301	10	b.	b.	PROPN
admet-1468	301	11	desai	desai	PROPN
admet-1468	301	12	,	,	PUNCT
admet-1468	301	13	j.a	j.a	PROPN
admet-1468	301	14	.	.	PROPN
admet-1468	301	15	shaikh	shaikh	PROPN
admet-1468	301	16	,	,	PUNCT
admet-1468	301	17	k.	k.	PROPN
admet-1468	301	18	ahmed	ahmed	PROPN
admet-1468	301	19	.	.	PUNCT
admet-1468	302	1	synthesis	synthesis	NOUN
admet-1468	302	2	of	of	ADP
admet-1468	302	3	3-(2-(subsituted(trifluoromethyl)phenylamino)acetyl)-2h	3-(2-(subsituted(trifluoromethyl)phenylamino)acetyl)-2h	PROPN
admet-1468	302	4	-	-	PUNCT
admet-1468	302	5	chromen-2	chromen-2	NUM
admet-1468	302	6	-	-	PUNCT
admet-1468	302	7	one	one	NUM
admet-1468	302	8	derivatives	derivative	NOUN
admet-1468	302	9	as	as	ADP
admet-1468	302	10	new	new	ADJ
admet-1468	302	11	anticancer	anticancer	NOUN
admet-1468	302	12	agents	agent	NOUN
admet-1468	302	13	.	.	PUNCT
admet-1468	303	1	current	current	ADJ
admet-1468	303	2	chemistry	chemistry	NOUN
admet-1468	303	3	letters	letter	NOUN
admet-1468	303	4	11(1	11(1	NUM
admet-1468	303	5	)	)	PUNCT
admet-1468	303	6	(	(	PUNCT
admet-1468	303	7	2022	2022	NUM
admet-1468	303	8	)	)	PUNCT
admet-1468	303	9	105–112	105–112	NUM
admet-1468	303	10	.	.	PUNCT
admet-1468	304	1	https://doi.org/10.5267/j.ccl.2021.8.004	https://doi.org/10.5267/j.ccl.2021.8.004	PROPN
admet-1468	304	2	.	.	PUNCT
admet-1468	305	1	[	[	X
admet-1468	305	2	3	3	NUM
admet-1468	305	3	]	]	X
admet-1468	305	4	y.	y.	PROPN
admet-1468	305	5	wu	wu	PROPN
admet-1468	305	6	,	,	PUNCT
admet-1468	305	7	j.	j.	PROPN
admet-1468	305	8	xu	xu	PROPN
admet-1468	305	9	,	,	PUNCT
admet-1468	305	10	y.	y.	PROPN
admet-1468	305	11	liu	liu	PROPN
admet-1468	305	12	,	,	PUNCT
admet-1468	305	13	y.	y.	PROPN
admet-1468	305	14	zeng	zeng	PROPN
admet-1468	305	15	,	,	PUNCT
admet-1468	305	16	g.	g.	PROPN
admet-1468	305	17	wu	wu	PROPN
admet-1468	305	18	.	.	PUNCT
admet-1468	306	1	a	a	DET
admet-1468	306	2	review	review	NOUN
admet-1468	306	3	on	on	ADP
admet-1468	306	4	antitumor	antitumor	PROPN
admet-1468	306	5	mechanisms	mechanism	NOUN
admet-1468	306	6	of	of	ADP
admet-1468	306	7	coumarins	coumarin	NOUN
admet-1468	306	8	.	.	PUNCT
admet-1468	307	1	front	front	ADJ
admet-1468	307	2	.	.	PUNCT
admet-1468	308	1	oncol	oncol	ADJ
admet-1468	308	2	.	.	PUNCT
admet-1468	309	1	10	10	NUM
admet-1468	309	2	(	(	PUNCT
admet-1468	309	3	2020	2020	NUM
admet-1468	309	4	)	)	PUNCT
admet-1468	309	5	592853	592853	NUM
admet-1468	309	6	.	.	PUNCT
admet-1468	310	1	https://doi.org/10.3389/fonc.2020.592853	https://doi.org/10.3389/fonc.2020.592853	PROPN
admet-1468	310	2	.	.	PUNCT
admet-1468	311	1	[	[	X
admet-1468	311	2	4	4	X
admet-1468	311	3	]	]	X
admet-1468	311	4	x.f	x.f	PROPN
admet-1468	311	5	.	.	PROPN
admet-1468	311	6	song	song	PROPN
admet-1468	311	7	,	,	PUNCT
admet-1468	311	8	j.	j.	PROPN
admet-1468	311	9	fan	fan	PROPN
admet-1468	311	10	,	,	PUNCT
admet-1468	311	11	l.	l.	PROPN
admet-1468	311	12	liu	liu	PROPN
admet-1468	311	13	,	,	PUNCT
admet-1468	311	14	x.f	x.f	PROPN
admet-1468	311	15	.	.	PROPN
admet-1468	311	16	liu	liu	PROPN
admet-1468	311	17	,	,	PUNCT
admet-1468	311	18	f.	f.	PROPN
admet-1468	311	19	gao	gao	PROPN
admet-1468	311	20	.	.	PUNCT
admet-1468	312	1	coumarin	coumarin	NOUN
admet-1468	312	2	derivatives	derivative	NOUN
admet-1468	312	3	with	with	ADP
admet-1468	312	4	anticancer	anticancer	NOUN
admet-1468	312	5	activities	activity	NOUN
admet-1468	312	6	:	:	PUNCT
admet-1468	312	7	an	an	DET
admet-1468	312	8	update	update	NOUN
admet-1468	312	9	.	.	PUNCT
admet-1468	313	1	arch	arch	NOUN
admet-1468	313	2	.	.	PUNCT
admet-1468	314	1	pharm	pharm	NOUN
admet-1468	314	2	.	.	PUNCT
admet-1468	315	1	(	(	PUNCT
admet-1468	315	2	weinheim	weinheim	PROPN
admet-1468	315	3	)	)	PUNCT
admet-1468	315	4	353	353	NUM
admet-1468	315	5	(	(	PUNCT
admet-1468	315	6	2020	2020	NUM
admet-1468	315	7	)	)	PUNCT
admet-1468	316	1	e2000025	e2000025	NOUN
admet-1468	316	2	.	.	PUNCT
admet-1468	317	1	https://doi.org/10.1002/ardp.202000025	https://doi.org/10.1002/ardp.202000025	NOUN
admet-1468	318	1	[	[	X
admet-1468	318	2	5	5	NUM
admet-1468	318	3	]	]	PUNCT
admet-1468	318	4	c.	c.	PROPN
admet-1468	318	5	kontogiorgis	kontogiorgis	PROPN
admet-1468	318	6	,	,	PUNCT
admet-1468	318	7	d.	d.	PROPN
admet-1468	318	8	hadjipavlou	hadjipavlou	PROPN
admet-1468	318	9	-	-	PUNCT
admet-1468	318	10	litina	litina	PROPN
admet-1468	318	11	.	.	PUNCT
admet-1468	319	1	biological	biological	ADJ
admet-1468	319	2	evaluation	evaluation	NOUN
admet-1468	319	3	of	of	ADP
admet-1468	319	4	several	several	ADJ
admet-1468	319	5	coumarin	coumarin	NOUN
admet-1468	319	6	derivatives	derivative	NOUN
admet-1468	319	7	designed	design	VERB
admet-1468	319	8	as	as	ADP
admet-1468	319	9	possible	possible	ADJ
admet-1468	319	10	anti	anti	ADJ
admet-1468	319	11	-	-	ADJ
admet-1468	319	12	inflammatory	inflammatory	ADJ
admet-1468	319	13	/	/	SYM
admet-1468	319	14	antioxidant	antioxidant	ADJ
admet-1468	319	15	agents	agent	NOUN
admet-1468	319	16	.	.	PUNCT
admet-1468	320	1	.j	.j	ADJ
admet-1468	320	2	enzyme	enzyme	NOUN
admet-1468	320	3	inhib	inhib	NOUN
admet-1468	320	4	.	.	PUNCT
admet-1468	321	1	med	med	PROPN
admet-1468	321	2	.	.	PROPN
admet-1468	321	3	chem	chem	PROPN
admet-1468	321	4	.	.	PUNCT
admet-1468	322	1	18	18	NUM
admet-1468	322	2	(	(	PUNCT
admet-1468	322	3	2003	2003	NUM
admet-1468	322	4	)	)	PUNCT
admet-1468	322	5	63	63	NUM
admet-1468	322	6	-	-	SYM
admet-1468	322	7	69	69	NUM
admet-1468	322	8	.	.	PUNCT
admet-1468	323	1	https://doi.org/10.1080/1475636031000069291	https://doi.org/10.1080/1475636031000069291	VERB
admet-1468	324	1	[	[	X
admet-1468	324	2	6	6	NUM
admet-1468	324	3	]	]	PUNCT
admet-1468	324	4	d.	d.	PROPN
admet-1468	324	5	feng	feng	PROPN
admet-1468	324	6	,	,	PUNCT
admet-1468	324	7	a.	a.	PROPN
admet-1468	324	8	zhang	zhang	PROPN
admet-1468	324	9	,	,	PUNCT
admet-1468	324	10	y.	y.	PROPN
admet-1468	324	11	yang	yang	PROPN
admet-1468	324	12	,	,	PUNCT
admet-1468	324	13	p.	p.	PROPN
admet-1468	324	14	yang	yang	PROPN
admet-1468	324	15	.	.	PUNCT
admet-1468	325	1	coumarin	coumarin	NOUN
admet-1468	325	2	-	-	PUNCT
admet-1468	325	3	containing	contain	VERB
admet-1468	325	4	hybrids	hybrid	NOUN
admet-1468	325	5	and	and	CCONJ
admet-1468	325	6	their	their	PRON
admet-1468	325	7	antibacterial	antibacterial	ADJ
admet-1468	325	8	activities	activity	NOUN
admet-1468	325	9	.	.	PUNCT
admet-1468	326	1	archiv	archiv	PROPN
admet-1468	326	2	der	der	PROPN
admet-1468	326	3	pharmazie	pharmazie	PROPN
admet-1468	326	4	353(6	353(6	NUM
admet-1468	326	5	)	)	PUNCT
admet-1468	326	6	(	(	PUNCT
admet-1468	326	7	2020	2020	NUM
admet-1468	326	8	)	)	PUNCT
admet-1468	327	1	e1900380	e1900380	NOUN
admet-1468	327	2	.	.	PUNCT
admet-1468	328	1	https://doi.org/10.1002/ardp.201900380	https://doi.org/10.1002/ardp.201900380	VERB
admet-1468	329	1	[	[	X
admet-1468	329	2	7	7	NUM
admet-1468	329	3	]	]	X
admet-1468	329	4	y.k	y.k	PROPN
admet-1468	329	5	.	.	PROPN
admet-1468	329	6	al	al	PROPN
admet-1468	329	7	-	-	PUNCT
admet-1468	329	8	majedy	majedy	NOUN
admet-1468	329	9	,	,	PUNCT
admet-1468	329	10	a.a.h	a.a.h	PROPN
admet-1468	329	11	.	.	PUNCT
admet-1468	329	12	kadhum	kadhum	PROPN
admet-1468	329	13	,	,	PUNCT
admet-1468	329	14	a.a	a.a	PROPN
admet-1468	329	15	.	.	PROPN
admet-1468	329	16	al	al	PROPN
admet-1468	329	17	-	-	PUNCT
admet-1468	329	18	amiery	amiery	PROPN
admet-1468	329	19	,	,	PUNCT
admet-1468	329	20	a.b	a.b	PROPN
admet-1468	329	21	.	.	PROPN
admet-1468	329	22	mohamad	mohamad	PROPN
admet-1468	329	23	.	.	PUNCT
admet-1468	329	24	coumarins	coumarin	NOUN
admet-1468	329	25	:	:	PUNCT
admet-1468	329	26	the	the	DET
admet-1468	329	27	antimicrobial	antimicrobial	ADJ
admet-1468	329	28	agents	agent	NOUN
admet-1468	329	29	.	.	PUNCT
admet-1468	330	1	sys	sys	AUX
admet-1468	330	2	.	.	PROPN
admet-1468	330	3	rev	rev	PROPN
admet-1468	330	4	.	.	PROPN
admet-1468	330	5	pharm	pharm	PROPN
admet-1468	330	6	.	.	PUNCT
admet-1468	331	1	8(1	8(1	NOUN
admet-1468	331	2	)	)	PUNCT
admet-1468	331	3	(	(	PUNCT
admet-1468	331	4	2017	2017	NUM
admet-1468	331	5	)	)	PUNCT
admet-1468	331	6	24	24	NUM
admet-1468	331	7	-	-	SYM
admet-1468	331	8	30	30	NUM
admet-1468	331	9	.	.	PUNCT
admet-1468	332	1	http://dx.doi.org/10.5530/srp.2017.1.11	http://dx.doi.org/10.5530/srp.2017.1.11	PROPN
admet-1468	333	1	[	[	X
admet-1468	333	2	8	8	NUM
admet-1468	333	3	]	]	X
admet-1468	333	4	y.	y.	PROPN
admet-1468	333	5	wei	wei	PROPN
admet-1468	333	6	,	,	PUNCT
admet-1468	333	7	w.	w.	PROPN
admet-1468	333	8	peng	peng	PROPN
admet-1468	333	9	,	,	PUNCT
admet-1468	333	10	d.	d.	PROPN
admet-1468	333	11	wang	wang	PROPN
admet-1468	333	12	,	,	PUNCT
admet-1468	333	13	s.h	s.h	PROPN
admet-1468	333	14	.	.	PROPN
admet-1468	333	15	hao	hao	PROPN
admet-1468	333	16	,	,	PUNCT
admet-1468	333	17	w.	w.	PROPN
admet-1468	333	18	w.	w.	PROPN
admet-1468	333	19	li	li	PROPN
admet-1468	333	20	,	,	PUNCT
admet-1468	333	21	f.	f.	PROPN
admet-1468	333	22	ding	ding	PROPN
admet-1468	333	23	.	.	PUNCT
admet-1468	334	1	design	design	NOUN
admet-1468	334	2	,	,	PUNCT
admet-1468	334	3	synthesis	synthesis	NOUN
admet-1468	334	4	,	,	PUNCT
admet-1468	334	5	antifungal	antifungal	ADJ
admet-1468	334	6	activity	activity	NOUN
admet-1468	334	7	,	,	PUNCT
admet-1468	334	8	and	and	CCONJ
admet-1468	334	9	3dqsar	3dqsar	NUM
admet-1468	334	10	of	of	ADP
admet-1468	334	11	coumarin	coumarin	NOUN
admet-1468	334	12	derivatives	derivative	NOUN
admet-1468	334	13	.	.	PUNCT
admet-1468	335	1	j.	j.	PROPN
admet-1468	335	2	pestic	pestic	PROPN
admet-1468	335	3	.	.	PUNCT
admet-1468	336	1	sci	sci	PROPN
admet-1468	336	2	.	.	PROPN
admet-1468	337	1	43	43	NUM
admet-1468	337	2	(	(	PUNCT
admet-1468	337	3	2018	2018	NUM
admet-1468	337	4	)	)	PUNCT
admet-1468	337	5	88	88	NUM
admet-1468	337	6	-	-	SYM
admet-1468	337	7	95	95	NUM
admet-1468	337	8	.	.	PUNCT
admet-1468	338	1	https://doi.org/10.1584%2fjpestics.d17075	https://doi.org/10.1584%2fjpestics.d17075	PROPN
admet-1468	339	1	[	[	X
admet-1468	339	2	9	9	NUM
admet-1468	339	3	]	]	PUNCT
admet-1468	339	4	z.	z.	PROPN
admet-1468	339	5	xu	xu	PROPN
admet-1468	339	6	,	,	PUNCT
admet-1468	339	7	q.	q.	PROPN
admet-1468	339	8	chen	chen	PROPN
admet-1468	339	9	,	,	PUNCT
admet-1468	339	10	y.	y.	PROPN
admet-1468	339	11	zhang	zhang	PROPN
admet-1468	339	12	,	,	PUNCT
admet-1468	339	13	c.	c.	PROPN
admet-1468	339	14	liang	liang	PROPN
admet-1468	339	15	.	.	PUNCT
admet-1468	340	1	coumarin	coumarin	NOUN
admet-1468	340	2	-	-	PUNCT
admet-1468	340	3	based	base	VERB
admet-1468	340	4	derivatives	derivative	NOUN
admet-1468	340	5	with	with	ADP
admet-1468	340	6	potential	potential	ADJ
admet-1468	340	7	anti	anti	ADJ
admet-1468	340	8	-	-	ADJ
admet-1468	340	9	hiv	hiv	ADJ
admet-1468	340	10	activity	activity	NOUN
admet-1468	340	11	.	.	PUNCT
admet-1468	341	1	fitoterapia	fitoterapia	PROPN
admet-1468	341	2	150	150	NUM
admet-1468	341	3	(	(	PUNCT
admet-1468	341	4	2021	2021	NUM
admet-1468	341	5	)	)	PUNCT
admet-1468	341	6	104863	104863	NUM
admet-1468	341	7	.	.	PUNCT
admet-1468	342	1	https://doi.org/10.1016/j.fitote.2021.104863	https://doi.org/10.1016/j.fitote.2021.104863	PROPN
admet-1468	342	2	[	[	X
admet-1468	342	3	10	10	NUM
admet-1468	342	4	]	]	X
admet-1468	342	5	h.	h.	PROPN
admet-1468	342	6	dai	dai	PROPN
admet-1468	342	7	,	,	PUNCT
admet-1468	342	8	m.	m.	PROPN
admet-1468	342	9	huang	huang	PROPN
admet-1468	342	10	,	,	PUNCT
admet-1468	342	11	j.	j.	PROPN
admet-1468	342	12	qian	qian	PROPN
admet-1468	342	13	,	,	PUNCT
admet-1468	342	14	j.	j.	PROPN
admet-1468	342	15	liu	liu	PROPN
admet-1468	342	16	,	,	PUNCT
admet-1468	342	17	c.	c.	PROPN
admet-1468	342	18	meng	meng	PROPN
admet-1468	342	19	,	,	PUNCT
admet-1468	342	20	y.	y.	PROPN
admet-1468	342	21	li	li	PROPN
admet-1468	342	22	,	,	PUNCT
admet-1468	342	23	g.	g.	PROPN
admet-1468	342	24	ming	ming	PROPN
admet-1468	342	25	,	,	PUNCT
admet-1468	342	26	t.	t.	PROPN
admet-1468	342	27	zhang	zhang	PROPN
admet-1468	342	28	,	,	PUNCT
admet-1468	342	29	s.	s.	PROPN
admet-1468	342	30	wang	wang	PROPN
admet-1468	342	31	,	,	PUNCT
admet-1468	342	32	y.	y.	PROPN
admet-1468	342	33	shi	shi	PROPN
admet-1468	342	34	,	,	PUNCT
admet-1468	342	35	y.	y.	PROPN
admet-1468	342	36	yao	yao	PROPN
admet-1468	342	37	,	,	PUNCT
admet-1468	342	38	s.	s.	PROPN
admet-1468	342	39	ge	ge	PROPN
admet-1468	342	40	,	,	PUNCT
admet-1468	342	41	y.	y.	PROPN
admet-1468	342	42	zhang	zhang	PROPN
admet-1468	342	43	,	,	PUNCT
admet-1468	342	44	y.	y.	PROPN
admet-1468	342	45	ling	ling	PROPN
admet-1468	342	46	.	.	PUNCT
admet-1468	343	1	excellent	excellent	ADJ
admet-1468	343	2	antitumor	antitumor	PROPN
admet-1468	343	3	and	and	CCONJ
admet-1468	343	4	antimetastatic	antimetastatic	ADJ
admet-1468	343	5	activities	activity	NOUN
admet-1468	343	6	based	base	VERB
admet-1468	343	7	on	on	ADP
admet-1468	343	8	novel	novel	ADJ
admet-1468	343	9	coumarin	coumarin	NOUN
admet-1468	343	10	/	/	SYM
admet-1468	343	11	pyrazole	pyrazole	NOUN
admet-1468	343	12	oxime	oxime	NOUN
admet-1468	343	13	hybrids	hybrid	NOUN
admet-1468	343	14	.	.	PUNCT
admet-1468	344	1	eur	eur	PROPN
admet-1468	344	2	.	.	PUNCT
admet-1468	345	1	j.	j.	PROPN
admet-1468	345	2	med	med	PROPN
admet-1468	345	3	.	.	PROPN
admet-1468	345	4	chem	chem	PROPN
admet-1468	345	5	.	.	PUNCT
admet-1468	346	1	166	166	NUM
admet-1468	346	2	(	(	PUNCT
admet-1468	346	3	2019	2019	NUM
admet-1468	346	4	)	)	PUNCT
admet-1468	346	5	470	470	NUM
admet-1468	346	6	-	-	SYM
admet-1468	346	7	479	479	NUM
admet-1468	346	8	.	.	PUNCT
admet-1468	347	1	https://doi.org/10.1016/j.ejmech.2019.01.070	https://doi.org/10.1016/j.ejmech.2019.01.070	NOUN
admet-1468	347	2	[	[	X
admet-1468	347	3	11	11	NUM
admet-1468	347	4	]	]	X
admet-1468	347	5	n.	n.	NOUN
admet-1468	347	6	bhattarai	bhattarai	PROPN
admet-1468	347	7	,	,	PUNCT
admet-1468	347	8	a.a	a.a	PROPN
admet-1468	347	9	.	.	PROPN
admet-1468	347	10	kumbhar	kumbhar	PROPN
admet-1468	347	11	,	,	PUNCT
admet-1468	347	12	y.r	y.r	PROPN
admet-1468	347	13	.	.	PROPN
admet-1468	347	14	pokharel	pokharel	PROPN
admet-1468	347	15	,	,	PUNCT
admet-1468	347	16	p.	p.	PROPN
admet-1468	347	17	n.	n.	PROPN
admet-1468	347	18	yadav	yadav	PROPN
admet-1468	347	19	.	.	PUNCT
admet-1468	348	1	anticancer	anticancer	NOUN
admet-1468	348	2	potential	potential	NOUN
admet-1468	348	3	of	of	ADP
admet-1468	348	4	coumarin	coumarin	NOUN
admet-1468	348	5	and	and	CCONJ
admet-1468	348	6	its	its	PRON
admet-1468	348	7	derivatives	derivative	NOUN
admet-1468	348	8	.	.	PUNCT
admet-1468	349	1	mini	mini	PROPN
admet-1468	349	2	rev	rev	PROPN
admet-1468	349	3	.	.	PROPN
admet-1468	349	4	med	med	PROPN
admet-1468	349	5	.	.	PROPN
admet-1468	349	6	chem	chem	PROPN
admet-1468	349	7	.	.	PUNCT
admet-1468	350	1	21	21	NUM
admet-1468	350	2	(	(	PUNCT
admet-1468	350	3	2021	2021	NUM
admet-1468	350	4	)	)	PUNCT
admet-1468	350	5	2996	2996	NUM
admet-1468	350	6	-	-	SYM
admet-1468	350	7	3029	3029	NUM
admet-1468	350	8	.	.	PUNCT
admet-1468	351	1	https://doi.org/10.2174/1389557521666210405160323	https://doi.org/10.2174/1389557521666210405160323	NOUN
admet-1468	352	1	[	[	X
admet-1468	352	2	12	12	NUM
admet-1468	352	3	]	]	X
admet-1468	352	4	p.r	p.r	PROPN
admet-1468	352	5	.	.	PROPN
admet-1468	352	6	finn	finn	PROPN
admet-1468	352	7	.	.	PUNCT
admet-1468	353	1	motivation	motivation	NOUN
admet-1468	353	2	,	,	PUNCT
admet-1468	353	3	working	working	NOUN
admet-1468	353	4	memory	memory	NOUN
admet-1468	353	5	,	,	PUNCT
admet-1468	353	6	and	and	CCONJ
admet-1468	353	7	decision	decision	NOUN
admet-1468	353	8	making	making	NOUN
admet-1468	353	9	:	:	PUNCT
admet-1468	353	10	a	a	DET
admet-1468	353	11	cognitive	cognitive	ADJ
admet-1468	353	12	-	-	PUNCT
admet-1468	353	13	motivational	motivational	ADJ
admet-1468	353	14	theory	theory	NOUN
admet-1468	353	15	of	of	ADP
admet-1468	353	16	personality	personality	NOUN
admet-1468	353	17	vulnerability	vulnerability	NOUN
admet-1468	353	18	to	to	ADP
admet-1468	353	19	alcoholism	alcoholism	NOUN
admet-1468	353	20	.	.	PUNCT
admet-1468	354	1	behav	behav	PROPN
admet-1468	354	2	.	.	PUNCT
admet-1468	355	1	cogn	cogn	PROPN
admet-1468	355	2	.	.	PUNCT
admet-1468	356	1	neurosci	neurosci	PROPN
admet-1468	356	2	.	.	PUNCT
admet-1468	357	1	rev	rev	PROPN
admet-1468	357	2	.	.	PROPN
admet-1468	357	3	1	1	NUM
admet-1468	357	4	(	(	PUNCT
admet-1468	357	5	2002	2002	NUM
admet-1468	357	6	)	)	PUNCT
admet-1468	357	7	183	183	NUM
admet-1468	357	8	-	-	SYM
admet-1468	357	9	205	205	NUM
admet-1468	357	10	.	.	PUNCT
admet-1468	357	11	https://doi.org/10.1177/1534582302001003001	https://doi.org/10.1177/1534582302001003001	X
admet-1468	358	1	[	[	X
admet-1468	358	2	13	13	NUM
admet-1468	358	3	]	]	X
admet-1468	358	4	s.a	s.a	PROPN
admet-1468	358	5	.	.	PROPN
admet-1468	358	6	behzadi	behzadi	PROPN
admet-1468	358	7	,	,	PUNCT
admet-1468	358	8	e.	e.	PROPN
admet-1468	358	9	sheikhhosseini	sheikhhosseini	PROPN
admet-1468	358	10	,	,	PUNCT
admet-1468	358	11	s.a	s.a	PROPN
admet-1468	358	12	.	.	PROPN
admet-1468	358	13	ahmadi	ahmadi	PROPN
admet-1468	358	14	,	,	PUNCT
admet-1468	358	15	d.	d.	PROPN
admet-1468	358	16	ghazanfari	ghazanfari	PROPN
admet-1468	358	17	,	,	PUNCT
admet-1468	358	18	m.	m.	NOUN
admet-1468	358	19	akhgar	akhgar	PROPN
admet-1468	358	20	.	.	PUNCT
admet-1468	359	1	synthesis	synthesis	NOUN
admet-1468	359	2	and	and	CCONJ
admet-1468	359	3	characterization	characterization	NOUN
admet-1468	359	4	of	of	ADP
admet-1468	359	5	novel	novel	ADJ
admet-1468	359	6	biological	biological	ADJ
admet-1468	359	7	tetracoumarin	tetracoumarin	NOUN
admet-1468	359	8	derivatives	derivative	NOUN
admet-1468	359	9	bearing	bear	VERB
admet-1468	359	10	ether	ether	ADJ
admet-1468	359	11	moieties	moiety	NOUN
admet-1468	359	12	.	.	PUNCT
admet-1468	360	1	heterocyclic	heterocyclic	ADJ
admet-1468	360	2	comm	comm	NOUN
admet-1468	360	3	.	.	PUNCT
admet-1468	361	1	26(1	26(1	NUM
admet-1468	361	2	)	)	PUNCT
admet-1468	361	3	(	(	PUNCT
admet-1468	361	4	2020	2020	NUM
admet-1468	361	5	)	)	PUNCT
admet-1468	361	6	60	60	NUM
admet-1468	361	7	-	-	SYM
admet-1468	361	8	67	67	NUM
admet-1468	361	9	.	.	PUNCT
admet-1468	361	10	https://doi.org/10.1515/hc-2020-0009	https://doi.org/10.1515/hc-2020-0009	NOUN
admet-1468	362	1	[	[	X
admet-1468	362	2	14	14	NUM
admet-1468	362	3	]	]	X
admet-1468	362	4	c.	c.	PROPN
admet-1468	362	5	asche	asche	PROPN
admet-1468	362	6	.	.	PUNCT
admet-1468	363	1	antitumour	antitumour	NOUN
admet-1468	363	2	quinones	quinone	NOUN
admet-1468	363	3	.	.	PUNCT
admet-1468	364	1	mini	mini	PROPN
admet-1468	364	2	rev	rev	PROPN
admet-1468	364	3	.	.	PROPN
admet-1468	364	4	med	med	PROPN
admet-1468	364	5	.	.	PROPN
admet-1468	364	6	chem	chem	PROPN
admet-1468	364	7	.	.	PUNCT
admet-1468	365	1	5	5	NUM
admet-1468	365	2	(	(	PUNCT
admet-1468	365	3	2005	2005	NUM
admet-1468	365	4	)	)	PUNCT
admet-1468	365	5	449	449	NUM
admet-1468	365	6	-	-	SYM
admet-1468	365	7	467	467	NUM
admet-1468	365	8	.	.	NOUN
admet-1468	365	9	https://doi.org/10.2174/1389557053765556	https://doi.org/10.2174/1389557053765556	X
admet-1468	366	1	[	[	X
admet-1468	366	2	15	15	NUM
admet-1468	366	3	]	]	X
admet-1468	366	4	a.a	a.a	PROPN
admet-1468	366	5	.	.	PROPN
admet-1468	366	6	aly	aly	PROPN
admet-1468	366	7	,	,	PUNCT
admet-1468	366	8	a.a	a.a	PROPN
admet-1468	366	9	.	.	PROPN
admet-1468	366	10	hassan	hassan	PROPN
admet-1468	366	11	,	,	PUNCT
admet-1468	366	12	n.k	n.k	PROPN
admet-1468	366	13	.	.	PROPN
admet-1468	366	14	mohamed	mohamed	PROPN
admet-1468	366	15	,	,	PUNCT
admet-1468	366	16	m.	m.	PROPN
admet-1468	366	17	ramadan	ramadan	PROPN
admet-1468	366	18	,	,	PUNCT
admet-1468	366	19	a.s	a.s	PROPN
admet-1468	366	20	.	.	PROPN
admet-1468	366	21	abd	abd	PROPN
admet-1468	366	22	el	el	PROPN
admet-1468	366	23	-	-	PROPN
admet-1468	366	24	aal	aal	PROPN
admet-1468	366	25	,	,	PUNCT
admet-1468	366	26	s.	s.	PROPN
admet-1468	366	27	braese	braese	PROPN
admet-1468	366	28	,	,	PUNCT
admet-1468	366	29	m.	m.	NOUN
admet-1468	366	30	nieger	nieger	NOUN
admet-1468	366	31	.	.	PUNCT
admet-1468	367	1	synthesis	synthesis	NOUN
admet-1468	367	2	of	of	ADP
admet-1468	367	3	quinone	quinone	NOUN
admet-1468	367	4	-	-	PUNCT
admet-1468	367	5	based	base	VERB
admet-1468	367	6	heterocycles	heterocycle	NOUN
admet-1468	367	7	of	of	ADP
admet-1468	367	8	broad	broad	ADJ
admet-1468	367	9	-	-	PUNCT
admet-1468	367	10	spectrum	spectrum	NOUN
admet-1468	367	11	anticancer	anticancer	NOUN
admet-1468	367	12	activity	activity	NOUN
admet-1468	367	13	.	.	PUNCT
admet-1468	368	1	j.	j.	PROPN
admet-1468	368	2	chem	chem	PROPN
admet-1468	368	3	.	.	PUNCT
admet-1468	369	1	res	re	NOUN
admet-1468	369	2	.	.	PUNCT
admet-1468	370	1	45(5	45(5	PROPN
admet-1468	370	2	-	-	PUNCT
admet-1468	370	3	6)(2021	6)(2021	NUM
admet-1468	370	4	)	)	PUNCT
admet-1468	370	5	562571	562571	NUM
admet-1468	370	6	.	.	PUNCT
admet-1468	371	1	https://doi.org/10.1177/1747519820959737	https://doi.org/10.1177/1747519820959737	PUNCT
admet-1468	372	1	[	[	X
admet-1468	372	2	16	16	NUM
admet-1468	372	3	]	]	X
admet-1468	372	4	h.	h.	PROPN
admet-1468	372	5	shaterzadeh	shaterzadeh	PROPN
admet-1468	372	6	-	-	PUNCT
admet-1468	372	7	yazdi	yazdi	NOUN
admet-1468	372	8	,	,	PUNCT
admet-1468	372	9	m.f	m.f	PROPN
admet-1468	372	10	.	.	PROPN
admet-1468	372	11	noorbakhsh	noorbakhsh	PROPN
admet-1468	372	12	,	,	PUNCT
admet-1468	372	13	f.	f.	PROPN
admet-1468	372	14	hayati	hayati	PROPN
admet-1468	372	15	,	,	PUNCT
admet-1468	372	16	s.	s.	PROPN
admet-1468	372	17	samarghandian	samarghandian	PROPN
admet-1468	372	18	,	,	PUNCT
admet-1468	372	19	t.	t.	PROPN
admet-1468	372	20	farkhondeh	farkhondeh	PROPN
admet-1468	372	21	.	.	PUNCT
admet-1468	373	1	immunomodulatory	immunomodulatory	ADJ
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admet-1468	373	3	anti	anti	ADJ
admet-1468	373	4	-	-	ADJ
admet-1468	373	5	inflammatory	inflammatory	ADJ
admet-1468	373	6	effects	effect	NOUN
admet-1468	373	7	of	of	ADP
admet-1468	373	8	thymoquinone	thymoquinone	NOUN
admet-1468	373	9	.	.	PUNCT
admet-1468	374	1	cardiovasc	cardiovasc	PROPN
admet-1468	374	2	hematol	hematol	PROPN
admet-1468	374	3	disord	disord	NOUN
admet-1468	374	4	drug	drug	NOUN
admet-1468	374	5	targets	target	NOUN
admet-1468	374	6	18	18	NUM
admet-1468	374	7	(	(	PUNCT
admet-1468	374	8	2018	2018	NUM
admet-1468	374	9	)	)	PUNCT
admet-1468	374	10	52	52	NUM
admet-1468	374	11	-	-	SYM
admet-1468	374	12	60	60	NUM
admet-1468	374	13	.	.	PUNCT
admet-1468	375	1	https://doi.org/10.2174/1871529x18666180212114816	https://doi.org/10.2174/1871529x18666180212114816	PROPN
admet-1468	376	1	[	[	X
admet-1468	376	2	17	17	NUM
admet-1468	376	3	]	]	X
admet-1468	376	4	k.w	k.w	PROPN
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admet-1468	376	6	wellington	wellington	PROPN
admet-1468	376	7	,	,	PUNCT
admet-1468	376	8	n.i	n.i	PROPN
admet-1468	376	9	.	.	PROPN
admet-1468	376	10	kolesnikova	kolesnikova	PROPN
admet-1468	376	11	,	,	PUNCT
admet-1468	376	12	n.b.p	n.b.p	PROPN
admet-1468	376	13	.	.	PROPN
admet-1468	376	14	nyoka	nyoka	PROPN
admet-1468	376	15	,	,	PUNCT
admet-1468	376	16	l.j	l.j	PROPN
admet-1468	376	17	.	.	PROPN
admet-1468	376	18	mcgaw	mcgaw	PROPN
admet-1468	376	19	.	.	PUNCT
admet-1468	377	1	investigation	investigation	NOUN
admet-1468	377	2	of	of	ADP
admet-1468	377	3	the	the	DET
admet-1468	377	4	antimicrobial	antimicrobial	ADJ
admet-1468	377	5	and	and	CCONJ
admet-1468	377	6	anticancer	anticancer	NOUN
admet-1468	377	7	activity	activity	NOUN
admet-1468	377	8	of	of	ADP
admet-1468	377	9	aminonaphthoquinones	aminonaphthoquinone	NOUN
admet-1468	377	10	.	.	PUNCT
admet-1468	378	1	drug	drug	PROPN
admet-1468	378	2	dev	dev	PROPN
admet-1468	378	3	.	.	PROPN
admet-1468	378	4	re.s	re.s	PROPN
admet-1468	378	5	80	80	NUM
admet-1468	378	6	(	(	PUNCT
admet-1468	378	7	2019	2019	NUM
admet-1468	378	8	)	)	PUNCT
admet-1468	378	9	138	138	NUM
admet-1468	378	10	-	-	SYM
admet-1468	378	11	146	146	NUM
admet-1468	378	12	.	.	PUNCT
admet-1468	379	1	https://doi.org/10.1002/ddr.21477	https://doi.org/10.1002/ddr.21477	NOUN
admet-1468	379	2	[	[	X
admet-1468	379	3	18	18	NUM
admet-1468	379	4	]	]	X
admet-1468	379	5	k.w	k.w	PROPN
admet-1468	379	6	.	.	PROPN
admet-1468	379	7	wellington	wellington	PROPN
admet-1468	379	8	.	.	PUNCT
admet-1468	380	1	understanding	understand	VERB
admet-1468	380	2	cancer	cancer	NOUN
admet-1468	380	3	and	and	CCONJ
admet-1468	380	4	anticancer	anticancer	NOUN
admet-1468	380	5	activities	activity	NOUN
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admet-1468	380	7	naphthoquinones	naphthoquinone	NOUN
admet-1468	380	8	-	-	PUNCT
admet-1468	380	9	a	a	DET
admet-1468	380	10	review	review	NOUN
admet-1468	380	11	.	.	PUNCT
admet-1468	381	1	rsc	rsc	PROPN
admet-1468	381	2	adv	adv	PROPN
admet-1468	381	3	.	.	PROPN
admet-1468	381	4	5	5	NUM
admet-1468	381	5	(	(	PUNCT
admet-1468	381	6	2015	2015	NUM
admet-1468	381	7	)	)	PUNCT
admet-1468	381	8	20309	20309	NUM
admet-1468	381	9	-	-	SYM
admet-1468	381	10	20338	20338	NUM
admet-1468	381	11	.	.	PUNCT
admet-1468	382	1	https://doi.org/10.1039/c4ra13547d	https://doi.org/10.1039/c4ra13547d	PROPN
admet-1468	382	2	https://doi.org/10.3390/50200099	https://doi.org/10.3390/50200099	VERB
admet-1468	382	3	https://doi.org/10.5267/j.ccl.2021.8.004	https://doi.org/10.5267/j.ccl.2021.8.004	PROPN
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admet-1468	382	8	http://dx.doi.org/10.5530/srp.2017.1.11	http://dx.doi.org/10.5530/srp.2017.1.11	PROPN
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admet-1468	382	25	&	&	CCONJ
admet-1468	382	26	dmpk	dmpk	PROPN
admet-1468	382	27	11(1	11(1	NUM
admet-1468	382	28	)	)	PUNCT
admet-1468	382	29	(	(	PUNCT
admet-1468	382	30	2023	2023	NUM
admet-1468	382	31	)	)	PUNCT
admet-1468	382	32	81	81	NUM
admet-1468	382	33	-	-	SYM
admet-1468	382	34	96	96	NUM
admet-1468	382	35	coumarin	coumarin	NOUN
admet-1468	382	36	-	-	PUNCT
admet-1468	382	37	quinone	quinone	NOUN
admet-1468	382	38	hybrids	hybrid	NOUN
admet-1468	382	39	doi	doi	NOUN
admet-1468	382	40	:	:	PUNCT
admet-1468	382	41	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	382	42	95	95	NUM
admet-1468	383	1	[	[	SYM
admet-1468	383	2	19	19	NUM
admet-1468	383	3	]	]	X
admet-1468	383	4	d.	d.	PROPN
admet-1468	383	5	bhasin	bhasin	PROPN
admet-1468	383	6	,	,	PUNCT
admet-1468	383	7	s.n	s.n	PROPN
admet-1468	383	8	.	.	PROPN
admet-1468	383	9	chettiar	chettiar	PROPN
admet-1468	383	10	,	,	PUNCT
admet-1468	383	11	j.p	j.p	PROPN
admet-1468	383	12	.	.	PROPN
admet-1468	383	13	etter	etter	PROPN
admet-1468	383	14	,	,	PUNCT
admet-1468	383	15	m.	m.	NOUN
admet-1468	383	16	mok	mok	PROPN
admet-1468	383	17	,	,	PUNCT
admet-1468	383	18	p.k	p.k	PROPN
admet-1468	383	19	.	.	PUNCT
admet-1468	383	20	li	li	PROPN
admet-1468	383	21	.	.	PROPN
admet-1468	383	22	anticancer	anticancer	NOUN
admet-1468	383	23	activity	activity	NOUN
admet-1468	383	24	and	and	CCONJ
admet-1468	383	25	sar	sar	PROPN
admet-1468	383	26	studies	study	NOUN
admet-1468	383	27	of	of	ADP
admet-1468	383	28	substituted	substitute	VERB
admet-1468	383	29	1,4	1,4	NOUN
admet-1468	383	30	-	-	PUNCT
admet-1468	383	31	naphthoquinones	naphthoquinone	NOUN
admet-1468	383	32	.	.	PUNCT
admet-1468	384	1	bioorg	bioorg	PROPN
admet-1468	384	2	.	.	PUNCT
admet-1468	385	1	med	med	PROPN
admet-1468	385	2	.	.	PROPN
admet-1468	385	3	chem	chem	PROPN
admet-1468	385	4	.	.	PUNCT
admet-1468	386	1	21	21	NUM
admet-1468	386	2	(	(	PUNCT
admet-1468	386	3	2013	2013	NUM
admet-1468	386	4	)	)	PUNCT
admet-1468	386	5	4662	4662	NUM
admet-1468	386	6	-	-	SYM
admet-1468	386	7	4669	4669	NUM
admet-1468	386	8	.	.	PUNCT
admet-1468	387	1	https://doi.org/10.1016%2fj.bmc.2013.05.017	https://doi.org/10.1016%2fj.bmc.2013.05.017	PUNCT
admet-1468	388	1	[	[	X
admet-1468	388	2	20	20	NUM
admet-1468	388	3	]	]	PUNCT
admet-1468	388	4	m.	m.	NOUN
admet-1468	388	5	kadela	kadela	PROPN
admet-1468	388	6	-	-	PUNCT
admet-1468	388	7	tomanek	tomanek	NOUN
admet-1468	388	8	,	,	PUNCT
admet-1468	388	9	e.	e.	PROPN
admet-1468	388	10	bębenek	bębenek	PROPN
admet-1468	388	11	,	,	PUNCT
admet-1468	388	12	e.	e.	PROPN
admet-1468	388	13	chrobak	chrobak	PROPN
admet-1468	388	14	,	,	PUNCT
admet-1468	388	15	m.	m.	PROPN
admet-1468	388	16	latocha	latocha	PROPN
admet-1468	388	17	,	,	PUNCT
admet-1468	388	18	s.	s.	PROPN
admet-1468	388	19	boryczka	boryczka	PROPN
admet-1468	388	20	.	.	PUNCT
admet-1468	389	1	alkoxy	alkoxy	ADJ
admet-1468	389	2	and	and	CCONJ
admet-1468	389	3	enediyne	enediyne	PROPN
admet-1468	389	4	derivatives	derivative	NOUN
admet-1468	389	5	containing	contain	VERB
admet-1468	389	6	1,4	1,4	NOUN
admet-1468	389	7	-	-	PUNCT
admet-1468	389	8	benzoquinone	benzoquinone	VERB
admet-1468	389	9	subunits	subunit	NOUN
admet-1468	389	10	-	-	PUNCT
admet-1468	389	11	synthesis	synthesis	NOUN
admet-1468	389	12	and	and	CCONJ
admet-1468	389	13	antitumor	antitumor	NOUN
admet-1468	389	14	activity	activity	NOUN
admet-1468	389	15	.	.	PUNCT
admet-1468	390	1	molecules	molecule	NOUN
admet-1468	390	2	22	22	NUM
admet-1468	390	3	(	(	PUNCT
admet-1468	390	4	2017	2017	NUM
admet-1468	390	5	)	)	PUNCT
admet-1468	390	6	e447	e447	PROPN
admet-1468	390	7	.	.	PUNCT
admet-1468	391	1	https://doi.org/10.3390%2fmolecules22030447	https://doi.org/10.3390%2fmolecules22030447	PRON
admet-1468	391	2	[	[	X
admet-1468	391	3	21	21	NUM
admet-1468	391	4	]	]	X
admet-1468	391	5	i.	i.	PROPN
admet-1468	391	6	abraham	abraham	PROPN
admet-1468	391	7	,	,	PUNCT
admet-1468	391	8	r.	r.	PROPN
admet-1468	391	9	joshi	joshi	PROPN
admet-1468	391	10	,	,	PUNCT
admet-1468	391	11	p.	p.	NOUN
admet-1468	391	12	pardasani	pardasani	NOUN
admet-1468	391	13	,	,	PUNCT
admet-1468	391	14	r.t	r.t	PROPN
admet-1468	391	15	.	.	PROPN
admet-1468	391	16	pardasani	pardasani	PROPN
admet-1468	391	17	.	.	PUNCT
admet-1468	392	1	recent	recent	ADJ
admet-1468	392	2	advances	advance	NOUN
admet-1468	392	3	in	in	ADP
admet-1468	392	4	1,4	1,4	NOUN
admet-1468	392	5	-	-	PUNCT
admet-1468	392	6	benzoquinone	benzoquinone	NOUN
admet-1468	392	7	chemistry	chemistry	NOUN
admet-1468	392	8	.	.	PUNCT
admet-1468	393	1	j.	j.	PROPN
admet-1468	393	2	braz	braz	PROPN
admet-1468	393	3	.	.	PUNCT
admet-1468	393	4	chem	chem	PROPN
admet-1468	393	5	.	.	PUNCT
admet-1468	394	1	soc	soc	PROPN
admet-1468	394	2	.	.	PUNCT
admet-1468	395	1	22(3	22(3	NUM
admet-1468	395	2	)	)	PUNCT
admet-1468	395	3	2011	2011	NUM
admet-1468	395	4	385	385	NUM
admet-1468	395	5	-	-	SYM
admet-1468	395	6	421	421	NUM
admet-1468	395	7	.	.	PUNCT
admet-1468	396	1	https://doi.org/10.1590/s0103-50532011000300002	https://doi.org/10.1590/s0103-50532011000300002	NOUN
admet-1468	397	1	[	[	X
admet-1468	397	2	22	22	NUM
admet-1468	397	3	]	]	X
admet-1468	397	4	s.p	s.p	PROPN
admet-1468	397	5	.	.	PUNCT
admet-1468	397	6	gupta	gupta	PROPN
admet-1468	397	7	.	.	PUNCT
admet-1468	398	1	quantitative	quantitative	ADJ
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admet-1468	398	3	-	-	PUNCT
admet-1468	398	4	activity	activity	NOUN
admet-1468	398	5	relationship	relationship	NOUN
admet-1468	398	6	studies	study	NOUN
admet-1468	398	7	on	on	ADP
admet-1468	398	8	anticancer	anticancer	NOUN
admet-1468	398	9	drugs	drug	NOUN
admet-1468	398	10	.	.	PUNCT
admet-1468	399	1	chem	chem	PROPN
admet-1468	399	2	.	.	PUNCT
admet-1468	400	1	rev	rev	PROPN
admet-1468	400	2	.	.	PROPN
admet-1468	400	3	94	94	NUM
admet-1468	400	4	(	(	PUNCT
admet-1468	400	5	1994	1994	NUM
admet-1468	400	6	)	)	PUNCT
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admet-1468	400	8	.	.	PUNCT
admet-1468	401	1	https://doi.org/10.1021/cr00030a003	https://doi.org/10.1021/cr00030a003	PROPN
admet-1468	401	2	[	[	X
admet-1468	401	3	23	23	NUM
admet-1468	401	4	]	]	X
admet-1468	401	5	a.j	a.j	PROPN
admet-1468	401	6	.	.	PROPN
admet-1468	401	7	m.	m.	PROPN
admet-1468	401	8	da	da	PROPN
admet-1468	401	9	silva	silva	PROPN
admet-1468	401	10	,	,	PUNCT
admet-1468	401	11	c.d	c.d	PROPN
admet-1468	401	12	.	.	PROPN
admet-1468	401	13	netto	netto	PROPN
admet-1468	401	14	,	,	PUNCT
admet-1468	401	15	w.	w.	PROPN
admet-1468	401	16	pacienza	pacienza	PROPN
admet-1468	401	17	-	-	PUNCT
admet-1468	401	18	lima	lima	PROPN
admet-1468	401	19	,	,	PUNCT
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admet-1468	401	23	-	-	PUNCT
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admet-1468	401	40	.	.	PUNCT
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admet-1468	402	2	,	,	PUNCT
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admet-1468	402	8	pentacyclic	pentacyclic	ADJ
admet-1468	402	9	1,4naphthoquinone	1,4naphthoquinone	NUM
admet-1468	402	10	derivatives	derivative	NOUN
admet-1468	402	11	.	.	PUNCT
admet-1468	403	1	j.	j.	PROPN
admet-1468	403	2	braz	braz	PROPN
admet-1468	403	3	.	.	PUNCT
admet-1468	403	4	chem	chem	PROPN
admet-1468	403	5	.	.	PUNCT
admet-1468	404	1	soc	soc	PROPN
admet-1468	404	2	.	.	PUNCT
admet-1468	405	1	20(1	20(1	NUM
admet-1468	405	2	)	)	PUNCT
admet-1468	405	3	(	(	PUNCT
admet-1468	405	4	2009	2009	NUM
admet-1468	405	5	)	)	PUNCT
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admet-1468	405	7	-	-	SYM
admet-1468	405	8	182	182	NUM
admet-1468	405	9	.	.	PUNCT
admet-1468	406	1	http://dx.doi.org/10.1590/s0103-50532009000100026	http://dx.doi.org/10.1590/s0103-50532009000100026	PROPN
admet-1468	406	2	[	[	X
admet-1468	406	3	24	24	NUM
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admet-1468	406	6	.	.	PROPN
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admet-1468	406	8	,	,	PUNCT
admet-1468	406	9	g.g	g.g	PROPN
admet-1468	406	10	.	.	PROPN
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admet-1468	406	12	,	,	PUNCT
admet-1468	406	13	u.	u.	PROPN
admet-1468	406	14	bauer	bauer	PROPN
admet-1468	406	15	,	,	PUNCT
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admet-1468	406	19	,	,	PUNCT
admet-1468	407	1	l.w	l.w	PROPN
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admet-1468	407	4	.	.	PUNCT
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admet-1468	408	4	pcbs	pcb	NOUN
admet-1468	408	5	to	to	ADP
admet-1468	408	6	quinones	quinone	NOUN
admet-1468	408	7	:	:	PUNCT
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admet-1468	408	13	nucleophiles	nucleophile	NOUN
admet-1468	408	14	and	and	CCONJ
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admet-1468	408	16	of	of	ADP
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admet-1468	408	18	dismutase	dismutase	NOUN
admet-1468	408	19	.	.	PUNCT
admet-1468	409	1	chem	chem	NOUN
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admet-1468	410	1	re.s	re.s	PROPN
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admet-1468	410	3	.	.	PUNCT
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admet-1468	411	2	(	(	PUNCT
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admet-1468	411	6	-	-	SYM
admet-1468	411	7	629	629	NUM
admet-1468	411	8	.	.	PUNCT
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admet-1468	412	2	[	[	X
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admet-1468	412	8	.	.	PUNCT
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admet-1468	413	5	cytotoxicity	cytotoxicity	NOUN
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admet-1468	414	1	chem	chem	NOUN
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admet-1468	416	2	.	.	PUNCT
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admet-1468	417	6	-	-	SYM
admet-1468	417	7	41	41	NUM
admet-1468	417	8	.	.	PUNCT
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admet-1468	418	22	.	.	PROPN
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admet-1468	418	24	.	.	PUNCT
admet-1468	419	1	synthesis	synthesis	NOUN
admet-1468	419	2	and	and	CCONJ
admet-1468	419	3	antimalarial	antimalarial	ADJ
admet-1468	419	4	activity	activity	NOUN
admet-1468	419	5	of	of	ADP
admet-1468	419	6	2	2	NUM
admet-1468	419	7	-	-	PUNCT
admet-1468	419	8	aziridinyl	aziridinyl	NOUN
admet-1468	419	9	and	and	CCONJ
admet-1468	419	10	2,3	2,3	NUM
admet-1468	419	11	-	-	PUNCT
admet-1468	419	12	bis(aziridinyl)-1,4	bis(aziridinyl)-1,4	ADV
admet-1468	419	13	-	-	PUNCT
admet-1468	419	14	naphthoquinonyl	naphthoquinonyl	NOUN
admet-1468	419	15	sulfonate	sulfonate	NOUN
admet-1468	419	16	and	and	CCONJ
admet-1468	419	17	acylate	acylate	ADJ
admet-1468	419	18	derivatives	derivative	NOUN
admet-1468	419	19	.	.	PUNCT
admet-1468	420	1	j.	j.	PROPN
admet-1468	420	2	med	med	PROPN
admet-1468	420	3	.	.	PROPN
admet-1468	420	4	chem	chem	PROPN
admet-1468	420	5	.	.	PUNCT
admet-1468	421	1	34	34	NUM
admet-1468	421	2	(	(	PUNCT
admet-1468	421	3	1991	1991	NUM
admet-1468	421	4	)	)	PUNCT
admet-1468	421	5	1634	1634	NUM
admet-1468	421	6	-	-	SYM
admet-1468	421	7	1639	1639	NUM
admet-1468	421	8	.	.	PUNCT
admet-1468	422	1	https://doi.org/10.1021/jm00109a016	https://doi.org/10.1021/jm00109a016	PROPN
admet-1468	422	2	[	[	X
admet-1468	422	3	27	27	NUM
admet-1468	422	4	]	]	X
admet-1468	422	5	a.j	a.j	PROPN
admet-1468	422	6	.	.	PROPN
admet-1468	422	7	lin	lin	PROPN
admet-1468	422	8	,	,	PUNCT
admet-1468	422	9	b.j	b.j	PROPN
admet-1468	422	10	.	.	PROPN
admet-1468	422	11	lillis	lillis	PROPN
admet-1468	422	12	,	,	PUNCT
admet-1468	422	13	a.c	a.c	PROPN
admet-1468	422	14	.	.	PROPN
admet-1468	422	15	sartorelli	sartorelli	PROPN
admet-1468	422	16	.	.	PUNCT
admet-1468	423	1	potential	potential	ADJ
admet-1468	423	2	bioreductive	bioreductive	ADJ
admet-1468	423	3	alkylating	alkylate	VERB
admet-1468	423	4	agents	agent	NOUN
admet-1468	423	5	.	.	PUNCT
admet-1468	424	1	5	5	X
admet-1468	424	2	.	.	X
admet-1468	424	3	antineoplastic	antineoplastic	ADJ
admet-1468	424	4	activity	activity	NOUN
admet-1468	424	5	of	of	ADP
admet-1468	424	6	quinoline-5,8	quinoline-5,8	NOUN
admet-1468	424	7	-	-	PUNCT
admet-1468	424	8	diones	dione	NOUN
admet-1468	424	9	,	,	PUNCT
admet-1468	424	10	naphthazarins	naphthazarin	NOUN
admet-1468	424	11	,	,	PUNCT
admet-1468	424	12	and	and	CCONJ
admet-1468	424	13	naphthoquinones	naphthoquinone	NOUN
admet-1468	424	14	.	.	PUNCT
admet-1468	425	1	j.	j.	PROPN
admet-1468	425	2	med	med	PROPN
admet-1468	425	3	.	.	PROPN
admet-1468	425	4	chem	chem	PROPN
admet-1468	425	5	.	.	PUNCT
admet-1468	426	1	18	18	NUM
admet-1468	426	2	(	(	PUNCT
admet-1468	426	3	1975	1975	NUM
admet-1468	426	4	)	)	PUNCT
admet-1468	426	5	917	917	NUM
admet-1468	426	6	-	-	SYM
admet-1468	426	7	921	921	NUM
admet-1468	426	8	.	.	PUNCT
admet-1468	427	1	https://doi.org/10.1021/jm00243a012	https://doi.org/10.1021/jm00243a012	PROPN
admet-1468	427	2	[	[	X
admet-1468	427	3	28	28	NUM
admet-1468	427	4	]	]	X
admet-1468	427	5	n.g	n.g	PROPN
admet-1468	427	6	.	.	PROPN
admet-1468	427	7	deniz	deniz	PROPN
admet-1468	427	8	,	,	PUNCT
admet-1468	427	9	c.	c.	PROPN
admet-1468	427	10	ibis	ibis	PROPN
admet-1468	427	11	,	,	PUNCT
admet-1468	427	12	z.	z.	PROPN
admet-1468	427	13	gokmen	gokmen	PROPN
admet-1468	427	14	,	,	PUNCT
admet-1468	427	15	m.	m.	NOUN
admet-1468	427	16	stasevych	stasevych	PROPN
admet-1468	427	17	,	,	PUNCT
admet-1468	427	18	v.	v.	ADP
admet-1468	427	19	novikov	novikov	NOUN
admet-1468	427	20	,	,	PUNCT
admet-1468	427	21	o.	o.	PROPN
admet-1468	427	22	komarovska	komarovska	NOUN
admet-1468	427	23	-	-	PUNCT
admet-1468	427	24	porokhnyavets	porokhnyavet	NOUN
admet-1468	427	25	,	,	PUNCT
admet-1468	427	26	m.	m.	NOUN
admet-1468	427	27	ozyurek	ozyurek	PROPN
admet-1468	427	28	,	,	PUNCT
admet-1468	427	29	k.	k.	PROPN
admet-1468	427	30	guclu	guclu	PROPN
admet-1468	427	31	,	,	PUNCT
admet-1468	427	32	d.	d.	PROPN
admet-1468	427	33	karakas	karakas	PROPN
admet-1468	427	34	,	,	PUNCT
admet-1468	427	35	e.	e.	PROPN
admet-1468	427	36	ulukaya	ulukaya	PROPN
admet-1468	427	37	.	.	PUNCT
admet-1468	428	1	design	design	NOUN
admet-1468	428	2	,	,	PUNCT
admet-1468	428	3	synthesis	synthesis	NOUN
admet-1468	428	4	,	,	PUNCT
admet-1468	428	5	biological	biological	ADJ
admet-1468	428	6	evaluation	evaluation	NOUN
admet-1468	428	7	,	,	PUNCT
admet-1468	428	8	and	and	CCONJ
admet-1468	428	9	antioxidant	antioxidant	ADJ
admet-1468	428	10	and	and	CCONJ
admet-1468	428	11	cytotoxic	cytotoxic	ADJ
admet-1468	428	12	activity	activity	NOUN
admet-1468	428	13	of	of	ADP
admet-1468	428	14	heteroatom	heteroatom	NOUN
admet-1468	428	15	-	-	PUNCT
admet-1468	428	16	substituted	substitute	VERB
admet-1468	428	17	1,4	1,4	NUM
admet-1468	428	18	-	-	PUNCT
admet-1468	428	19	naphthoand	naphthoand	ADJ
admet-1468	428	20	benzoquinones	benzoquinone	NOUN
admet-1468	428	21	.	.	PUNCT
admet-1468	429	1	chem	chem	NOUN
admet-1468	429	2	.	.	PUNCT
admet-1468	430	1	pharm	pharm	NOUN
admet-1468	430	2	.	.	PUNCT
admet-1468	431	1	bull	bull	NOUN
admet-1468	431	2	.	.	PUNCT
admet-1468	432	1	(	(	PUNCT
admet-1468	432	2	tokyo	tokyo	PROPN
admet-1468	432	3	)	)	PUNCT
admet-1468	432	4	63(12	63(12	PROPN
admet-1468	432	5	)	)	PUNCT
admet-1468	432	6	(	(	PUNCT
admet-1468	432	7	2015	2015	NUM
admet-1468	432	8	)	)	PUNCT
admet-1468	432	9	1029	1029	NUM
admet-1468	432	10	-	-	SYM
admet-1468	432	11	1039	1039	NUM
admet-1468	432	12	.	.	PUNCT
admet-1468	433	1	https://doi.org/10.1248/cpb.c15-00607	https://doi.org/10.1248/cpb.c15-00607	PROPN
admet-1468	433	2	[	[	X
admet-1468	433	3	29	29	NUM
admet-1468	433	4	]	]	X
admet-1468	433	5	y.	y.	NOUN
admet-1468	433	6	isyaku	isyaku	PROPN
admet-1468	433	7	,	,	PUNCT
admet-1468	433	8	a.	a.	NOUN
admet-1468	433	9	uzairu	uzairu	PROPN
admet-1468	433	10	,	,	PUNCT
admet-1468	434	1	s.	s.	PROPN
admet-1468	434	2	uba	uba	PROPN
admet-1468	434	3	.	.	PUNCT
admet-1468	435	1	computational	computational	ADJ
admet-1468	435	2	studies	study	NOUN
admet-1468	435	3	of	of	ADP
admet-1468	435	4	a	a	DET
admet-1468	435	5	series	series	NOUN
admet-1468	435	6	of	of	ADP
admet-1468	435	7	2	2	NUM
admet-1468	435	8	-	-	PUNCT
admet-1468	435	9	substituted	substitute	VERB
admet-1468	435	10	phenyl-2	phenyl-2	NUM
admet-1468	435	11	-	-	PUNCT
admet-1468	435	12	oxo-	oxo-	NOUN
admet-1468	435	13	,	,	PUNCT
admet-1468	435	14	2hydroxyland	2hydroxyland	NUM
admet-1468	435	15	2	2	NUM
admet-1468	435	16	-	-	PUNCT
admet-1468	435	17	acylloxyethylsulfonamides	acylloxyethylsulfonamide	NOUN
admet-1468	435	18	as	as	ADP
admet-1468	435	19	potent	potent	ADJ
admet-1468	435	20	antifungal	antifungal	ADJ
admet-1468	435	21	agents	agent	NOUN
admet-1468	435	22	.	.	PUNCT
admet-1468	436	1	heliyon	heliyon	NOUN
admet-1468	436	2	6	6	NUM
admet-1468	436	3	(	(	PUNCT
admet-1468	436	4	2020	2020	NUM
admet-1468	436	5	)	)	PUNCT
admet-1468	436	6	e03724	e03724	NOUN
admet-1468	436	7	.	.	PUNCT
admet-1468	437	1	https://doi.org/10.1016/j.heliyon.2020.e03724	https://doi.org/10.1016/j.heliyon.2020.e03724	X
admet-1468	438	1	[	[	X
admet-1468	438	2	30	30	NUM
admet-1468	438	3	]	]	X
admet-1468	438	4	c.m	c.m	PROPN
admet-1468	438	5	.	.	PROPN
admet-1468	438	6	nisha	nisha	PROPN
admet-1468	438	7	,	,	PUNCT
admet-1468	438	8	a.	a.	PROPN
admet-1468	438	9	kumar	kumar	PROPN
admet-1468	438	10	,	,	PUNCT
admet-1468	438	11	p.	p.	PROPN
admet-1468	438	12	nair	nair	PROPN
admet-1468	438	13	,	,	PUNCT
admet-1468	438	14	n.	n.	PROPN
admet-1468	438	15	gupta	gupta	PROPN
admet-1468	438	16	,	,	PUNCT
admet-1468	438	17	c.	c.	PROPN
admet-1468	438	18	silakari	silakari	PROPN
admet-1468	438	19	,	,	PUNCT
admet-1468	438	20	t.	t.	PROPN
admet-1468	438	21	tripathi	tripathi	PROPN
admet-1468	438	22	,	,	PUNCT
admet-1468	438	23	a.	a.	PROPN
admet-1468	438	24	kumar	kumar	PROPN
admet-1468	438	25	.	.	PUNCT
admet-1468	439	1	molecular	molecular	ADJ
admet-1468	439	2	docking	docking	NOUN
admet-1468	439	3	and	and	CCONJ
admet-1468	439	4	in	in	ADP
admet-1468	439	5	silico	silico	NOUN
admet-1468	439	6	admet	admet	NOUN
admet-1468	439	7	study	study	NOUN
admet-1468	439	8	reveals	reveal	VERB
admet-1468	439	9	acylguanidine	acylguanidine	ADJ
admet-1468	439	10	7a	7a	NOUN
admet-1468	439	11	as	as	ADP
admet-1468	439	12	a	a	DET
admet-1468	439	13	potential	potential	ADJ
admet-1468	439	14	inhibitor	inhibitor	NOUN
admet-1468	439	15	of	of	ADP
admet-1468	439	16	β	β	NOUN
admet-1468	439	17	-	-	NOUN
admet-1468	439	18	secretase	secretase	NOUN
admet-1468	439	19	.	.	PUNCT
admet-1468	440	1	adv	adv	PROPN
admet-1468	440	2	.	.	PUNCT
admet-1468	441	1	bioinformatics	bioinformatic	NOUN
admet-1468	441	2	2016	2016	NUM
admet-1468	441	3	(	(	PUNCT
admet-1468	441	4	2016	2016	NUM
admet-1468	441	5	)	)	PUNCT
admet-1468	441	6	9258578	9258578	NUM
admet-1468	441	7	.	.	PUNCT
admet-1468	442	1	https://doi.org/10.1155/2016/9258578	https://doi.org/10.1155/2016/9258578	PROPN
admet-1468	443	1	[	[	X
admet-1468	443	2	31	31	NUM
admet-1468	443	3	]	]	SYM
admet-1468	443	4	d.b	d.b	PROPN
admet-1468	443	5	.	.	PROPN
admet-1468	443	6	singh	singh	PROPN
admet-1468	443	7	,	,	PUNCT
admet-1468	443	8	m.k	m.k	PROPN
admet-1468	443	9	.	.	PUNCT
admet-1468	443	10	gupta	gupta	PROPN
admet-1468	443	11	,	,	PUNCT
admet-1468	443	12	d.v	d.v	PROPN
admet-1468	443	13	.	.	PROPN
admet-1468	443	14	singh	singh	PROPN
admet-1468	443	15	,	,	PUNCT
admet-1468	443	16	s.k	s.k	PROPN
admet-1468	443	17	.	.	PROPN
admet-1468	443	18	singh	singh	PROPN
admet-1468	443	19	,	,	PUNCT
admet-1468	443	20	k.	k.	PROPN
admet-1468	443	21	misra	misra	PROPN
admet-1468	443	22	.	.	PUNCT
admet-1468	444	1	docking	docking	NOUN
admet-1468	444	2	and	and	CCONJ
admet-1468	444	3	in	in	ADP
admet-1468	444	4	silico	silico	NOUN
admet-1468	444	5	admet	admet	NOUN
admet-1468	444	6	studies	study	NOUN
admet-1468	444	7	of	of	ADP
admet-1468	444	8	noraristeromycin	noraristeromycin	PROPN
admet-1468	444	9	,	,	PUNCT
admet-1468	444	10	curcumin	curcumin	NOUN
admet-1468	444	11	and	and	CCONJ
admet-1468	444	12	its	its	PRON
admet-1468	444	13	derivatives	derivative	NOUN
admet-1468	444	14	with	with	ADP
admet-1468	444	15	plasmodium	plasmodium	NOUN
admet-1468	444	16	falciparum	falciparum	ADJ
admet-1468	444	17	sah	sah	NOUN
admet-1468	444	18	hydrolase	hydrolase	NOUN
admet-1468	444	19	:	:	PUNCT
admet-1468	444	20	a	a	DET
admet-1468	444	21	molecular	molecular	ADJ
admet-1468	444	22	drug	drug	NOUN
admet-1468	444	23	target	target	NOUN
admet-1468	444	24	against	against	ADP
admet-1468	444	25	malaria	malaria	NOUN
admet-1468	444	26	.	.	PUNCT
admet-1468	445	1	interdiscip	interdiscip	NOUN
admet-1468	445	2	.	.	PUNCT
admet-1468	446	1	sci	sci	PROPN
admet-1468	446	2	.	.	PROPN
admet-1468	446	3	5	5	NUM
admet-1468	446	4	(	(	PUNCT
admet-1468	446	5	2013	2013	NUM
admet-1468	446	6	)	)	PUNCT
admet-1468	446	7	1	1	NUM
admet-1468	446	8	-	-	SYM
admet-1468	446	9	12	12	NUM
admet-1468	446	10	.	.	PUNCT
admet-1468	447	1	https://doi.org/10.1007/s12539013-0147-z	https://doi.org/10.1007/s12539013-0147-z	PROPN
admet-1468	448	1	[	[	X
admet-1468	448	2	32	32	NUM
admet-1468	448	3	]	]	PUNCT
admet-1468	448	4	t.	t.	PROPN
admet-1468	448	5	żołek	żołek	PROPN
admet-1468	448	6	,	,	PUNCT
admet-1468	448	7	d.	d.	PROPN
admet-1468	448	8	maciejewska	maciejewska	PROPN
admet-1468	448	9	.	.	PUNCT
admet-1468	449	1	theoretical	theoretical	ADJ
admet-1468	449	2	evaluation	evaluation	NOUN
admet-1468	449	3	of	of	ADP
admet-1468	449	4	admet	admet	NOUN
admet-1468	449	5	properties	property	NOUN
admet-1468	449	6	for	for	ADP
admet-1468	449	7	coumarin	coumarin	NOUN
admet-1468	449	8	derivatives	derivative	NOUN
admet-1468	449	9	as	as	ADP
admet-1468	449	10	compounds	compound	NOUN
admet-1468	449	11	with	with	ADP
admet-1468	449	12	therapeutic	therapeutic	ADJ
admet-1468	449	13	potential	potential	NOUN
admet-1468	449	14	.	.	PUNCT
admet-1468	450	1	eur	eur	PROPN
admet-1468	450	2	.	.	PUNCT
admet-1468	451	1	j.	j.	PROPN
admet-1468	451	2	pharm	pharm	PROPN
admet-1468	451	3	.	.	PUNCT
admet-1468	452	1	sci	sci	PROPN
admet-1468	452	2	.	.	PROPN
admet-1468	453	1	109	109	NUM
admet-1468	453	2	(	(	PUNCT
admet-1468	453	3	2017	2017	NUM
admet-1468	453	4	)	)	PUNCT
admet-1468	453	5	486	486	NUM
admet-1468	453	6	-	-	SYM
admet-1468	453	7	502	502	NUM
admet-1468	453	8	.	.	PUNCT
admet-1468	454	1	https://doi.org/10.1016/j.ejps.2017.08.036	https://doi.org/10.1016/j.ejps.2017.08.036	PRON
admet-1468	454	2	[	[	X
admet-1468	454	3	33	33	NUM
admet-1468	454	4	]	]	PUNCT
admet-1468	454	5	m.	m.	NOUN
admet-1468	454	6	jenny	jenny	PROPN
admet-1468	454	7	,	,	PUNCT
admet-1468	454	8	m.	m.	PROPN
admet-1468	454	9	klieber	klieber	PROPN
admet-1468	454	10	,	,	PUNCT
admet-1468	454	11	d.	d.	PROPN
admet-1468	454	12	zaknun	zaknun	PROPN
admet-1468	454	13	,	,	PUNCT
admet-1468	454	14	s.	s.	PROPN
admet-1468	454	15	schroecksnadel	schroecksnadel	PROPN
admet-1468	454	16	,	,	PUNCT
admet-1468	454	17	k.	k.	PROPN
admet-1468	454	18	kurz	kurz	PROPN
admet-1468	454	19	,	,	PUNCT
admet-1468	454	20	m.	m.	NOUN
admet-1468	454	21	ledochowski	ledochowski	PROPN
admet-1468	454	22	,	,	PUNCT
admet-1468	454	23	h.	h.	PROPN
admet-1468	454	24	schennach	schennach	PROPN
admet-1468	454	25	,	,	PUNCT
admet-1468	454	26	d.	d.	PROPN
admet-1468	454	27	fuchs	fuchs	PROPN
admet-1468	454	28	.	.	PUNCT
admet-1468	455	1	in	in	ADP
admet-1468	455	2	vitro	vitro	X
admet-1468	455	3	testing	testing	NOUN
admet-1468	455	4	for	for	ADP
admet-1468	455	5	anti	anti	ADJ
admet-1468	455	6	-	-	ADJ
admet-1468	455	7	inflammatory	inflammatory	ADJ
admet-1468	455	8	properties	property	NOUN
admet-1468	455	9	of	of	ADP
admet-1468	455	10	compounds	compound	NOUN
admet-1468	455	11	employing	employ	VERB
admet-1468	455	12	peripheral	peripheral	ADJ
admet-1468	455	13	blood	blood	NOUN
admet-1468	455	14	mononuclear	mononuclear	ADJ
admet-1468	455	15	cells	cell	NOUN
admet-1468	455	16	freshly	freshly	ADV
admet-1468	455	17	isolated	isolate	VERB
admet-1468	455	18	from	from	ADP
admet-1468	455	19	healthy	healthy	ADJ
admet-1468	455	20	donors	donor	NOUN
admet-1468	455	21	.	.	PUNCT
admet-1468	456	1	inflamm	inflamm	PROPN
admet-1468	456	2	.	.	PUNCT
admet-1468	457	1	res	re	NOUN
admet-1468	457	2	.	.	PUNCT
admet-1468	458	1	60	60	NUM
admet-1468	458	2	(	(	PUNCT
admet-1468	458	3	2011	2011	NUM
admet-1468	458	4	)	)	PUNCT
admet-1468	458	5	127	127	NUM
admet-1468	458	6	-	-	SYM
admet-1468	458	7	135	135	NUM
admet-1468	458	8	.	.	PUNCT
admet-1468	458	9	https://dx.doi.org/10.1007/s00011-010-0244-y	https://dx.doi.org/10.1007/s00011-010-0244-y	PUNCT
admet-1468	459	1	[	[	X
admet-1468	459	2	34	34	NUM
admet-1468	459	3	]	]	X
admet-1468	459	4	o.	o.	PROPN
admet-1468	459	5	trott	trott	PROPN
admet-1468	459	6	,	,	PUNCT
admet-1468	459	7	a.j	a.j	PROPN
admet-1468	459	8	.	.	PROPN
admet-1468	459	9	olson	olson	PROPN
admet-1468	459	10	.	.	PUNCT
admet-1468	460	1	autodock	autodock	PROPN
admet-1468	460	2	vina	vina	PROPN
admet-1468	460	3	:	:	PUNCT
admet-1468	460	4	improving	improve	VERB
admet-1468	460	5	the	the	DET
admet-1468	460	6	speed	speed	NOUN
admet-1468	460	7	and	and	CCONJ
admet-1468	460	8	accuracy	accuracy	NOUN
admet-1468	460	9	of	of	ADP
admet-1468	460	10	docking	docking	NOUN
admet-1468	460	11	with	with	ADP
admet-1468	460	12	a	a	DET
admet-1468	460	13	new	new	ADJ
admet-1468	460	14	scoring	scoring	NOUN
admet-1468	460	15	function	function	NOUN
admet-1468	460	16	,	,	PUNCT
admet-1468	460	17	efficient	efficient	ADJ
admet-1468	460	18	optimization	optimization	NOUN
admet-1468	460	19	,	,	PUNCT
admet-1468	460	20	and	and	CCONJ
admet-1468	460	21	multithreading	multithreading	NOUN
admet-1468	460	22	.	.	PUNCT
admet-1468	461	1	j.	j.	PROPN
admet-1468	461	2	comput	comput	PROPN
admet-1468	461	3	.	.	PUNCT
admet-1468	462	1	chem	chem	NOUN
admet-1468	462	2	.	.	PUNCT
admet-1468	463	1	31	31	NUM
admet-1468	463	2	(	(	PUNCT
admet-1468	463	3	2010	2010	NUM
admet-1468	463	4	)	)	PUNCT
admet-1468	463	5	455	455	NUM
admet-1468	463	6	-	-	SYM
admet-1468	463	7	461	461	NUM
admet-1468	463	8	.	.	PUNCT
admet-1468	464	1	https://doi.org/10.1002%2fjcc.21334	https://doi.org/10.1002%2fjcc.21334	NOUN
admet-1468	464	2	https://doi.org/10.5599/admet.1468	https://doi.org/10.5599/admet.1468	NOUN
admet-1468	464	3	https://doi.org/10.1016%2fj.bmc.2013.05.017	https://doi.org/10.1016%2fj.bmc.2013.05.017	NOUN
admet-1468	464	4	https://doi.org/10.1016%2fj.bmc.2013.05.017	https://doi.org/10.1016%2fj.bmc.2013.05.017	ADP
admet-1468	464	5	https://doi.org/10.3390%2fmolecules22030447	https://doi.org/10.3390%2fmolecules22030447	VERB
admet-1468	464	6	https://doi.org/10.1590/s0103-50532011000300002	https://doi.org/10.1590/s0103-50532011000300002	NOUN
admet-1468	465	1	https://doi.org/10.1021/cr00030a003	https://doi.org/10.1021/cr00030a003	PROPN
admet-1468	465	2	http://dx.doi.org/10.1590/s0103-50532009000100026	http://dx.doi.org/10.1590/s0103-50532009000100026	PROPN
admet-1468	465	3	http://dx.doi.org/10.1590/s0103-50532009000100026	http://dx.doi.org/10.1590/s0103-50532009000100026	PROPN
admet-1468	465	4	https://doi.org/10.1021/tx950117e	https://doi.org/10.1021/tx950117e	X
admet-1468	465	5	https://doi.org/10.1016/0009-2797(91)90029-7	https://doi.org/10.1016/0009-2797(91)90029-7	VERB
admet-1468	465	6	https://doi.org/10.1021/jm00109a016	https://doi.org/10.1021/jm00109a016	PROPN
admet-1468	465	7	https://doi.org/10.1021/jm00243a012	https://doi.org/10.1021/jm00243a012	PROPN
admet-1468	465	8	https://doi.org/10.1248/cpb.c15-00607	https://doi.org/10.1248/cpb.c15-00607	ADJ
admet-1468	465	9	https://doi.org/10.1016/j.heliyon.2020.e03724	https://doi.org/10.1016/j.heliyon.2020.e03724	ADJ
admet-1468	465	10	https://doi.org/10.1155/2016/9258578	https://doi.org/10.1155/2016/9258578	PROPN
admet-1468	465	11	https://doi.org/10.1007/s12539-013-0147-z	https://doi.org/10.1007/s12539-013-0147-z	INTJ
admet-1468	465	12	https://doi.org/10.1007/s12539-013-0147-z	https://doi.org/10.1007/s12539-013-0147-z	INTJ
admet-1468	465	13	https://doi.org/10.1016/j.ejps.2017.08.036	https://doi.org/10.1016/j.ejps.2017.08.036	PROPN
admet-1468	465	14	https://doi.org/10.1016/j.ejps.2017.08.036	https://doi.org/10.1016/j.ejps.2017.08.036	PROPN
admet-1468	465	15	https://dx.doi.org/10.1007/s00011-010-0244-y	https://dx.doi.org/10.1007/s00011-010-0244-y	PUNCT
admet-1468	465	16	https://doi.org/10.1002%2fjcc.21334	https://doi.org/10.1002%2fjcc.21334	NOUN
admet-1468	465	17	a.	a.	NOUN
admet-1468	465	18	pangal	pangal	PROPN
admet-1468	465	19	and	and	CCONJ
admet-1468	465	20	k.	k.	PROPN
admet-1468	465	21	ahmed	ahmed	PROPN
admet-1468	465	22	admet	admet	PROPN
admet-1468	465	23	&	&	CCONJ
admet-1468	465	24	dmpk	dmpk	PROPN
admet-1468	465	25	11(1	11(1	NUM
admet-1468	465	26	)	)	PUNCT
admet-1468	465	27	(	(	PUNCT
admet-1468	465	28	2023	2023	NUM
admet-1468	465	29	)	)	PUNCT
admet-1468	465	30	81	81	NUM
admet-1468	465	31	-	-	SYM
admet-1468	465	32	96	96	NUM
admet-1468	465	33	96	96	NUM
admet-1468	466	1	[	[	SYM
admet-1468	466	2	35	35	NUM
admet-1468	466	3	]	]	X
admet-1468	466	4	n.	n.	PROPN
admet-1468	466	5	hashemi	hashemi	PROPN
admet-1468	466	6	goradel	goradel	PROPN
admet-1468	466	7	,	,	PUNCT
admet-1468	466	8	m.	m.	NOUN
admet-1468	466	9	najafi	najafi	PROPN
admet-1468	466	10	,	,	PUNCT
admet-1468	466	11	e.	e.	PROPN
admet-1468	466	12	salehi	salehi	PROPN
admet-1468	466	13	,	,	PUNCT
admet-1468	466	14	b.	b.	PROPN
admet-1468	466	15	farhood	farhood	PROPN
admet-1468	466	16	,	,	PUNCT
admet-1468	466	17	k.	k.	PROPN
admet-1468	466	18	mortezaee	mortezaee	PROPN
admet-1468	466	19	.	.	PUNCT
admet-1468	467	1	cyclooxygenase-2	cyclooxygenase-2	NUM
admet-1468	468	1	in	in	ADP
admet-1468	468	2	cancer	cancer	NOUN
admet-1468	468	3	:	:	PUNCT
admet-1468	468	4	a	a	DET
admet-1468	468	5	review	review	NOUN
admet-1468	468	6	.	.	PUNCT
admet-1468	469	1	j.	j.	PROPN
admet-1468	469	2	cell	cell	PROPN
admet-1468	469	3	physiol	physiol	PROPN
admet-1468	469	4	.	.	PUNCT
admet-1468	470	1	234	234	NUM
admet-1468	470	2	(	(	PUNCT
admet-1468	470	3	2019	2019	NUM
admet-1468	470	4	)	)	PUNCT
admet-1468	470	5	5683	5683	NUM
admet-1468	470	6	-	-	SYM
admet-1468	470	7	5699	5699	NUM
admet-1468	470	8	.	.	PUNCT
admet-1468	471	1	https://doi.org/10.1002/jcp.27411	https://doi.org/10.1002/jcp.27411	INTJ
admet-1468	472	1	[	[	X
admet-1468	472	2	36	36	NUM
admet-1468	472	3	]	]	PUNCT
admet-1468	472	4	k.	k.	PROPN
admet-1468	472	5	singh	singh	PROPN
admet-1468	472	6	,	,	PUNCT
admet-1468	472	7	a.	a.	NOUN
admet-1468	472	8	gangrade	gangrade	NOUN
admet-1468	472	9	,	,	PUNCT
admet-1468	472	10	a.	a.	PROPN
admet-1468	472	11	jana	jana	PROPN
admet-1468	472	12	,	,	PUNCT
admet-1468	472	13	b.b	b.b	PROPN
admet-1468	472	14	.	.	PROPN
admet-1468	472	15	mandal	mandal	PROPN
admet-1468	472	16	,	,	PUNCT
admet-1468	472	17	n.	n.	PROPN
admet-1468	472	18	das	das	PROPN
admet-1468	472	19	.	.	PROPN
admet-1468	473	1	design	design	NOUN
admet-1468	473	2	,	,	PUNCT
admet-1468	473	3	synthesis	synthesis	NOUN
admet-1468	473	4	,	,	PUNCT
admet-1468	473	5	characterization	characterization	NOUN
admet-1468	473	6	,	,	PUNCT
admet-1468	473	7	and	and	CCONJ
admet-1468	473	8	antiproliferative	antiproliferative	ADJ
admet-1468	473	9	activity	activity	NOUN
admet-1468	473	10	of	of	ADP
admet-1468	473	11	organoplatinum	organoplatinum	ADJ
admet-1468	473	12	compounds	compound	NOUN
admet-1468	473	13	bearing	bear	VERB
admet-1468	473	14	a	a	DET
admet-1468	473	15	1,2,3	1,2,3	NUM
admet-1468	473	16	-	-	PUNCT
admet-1468	473	17	triazole	triazole	ADJ
admet-1468	473	18	ring	ring	NOUN
admet-1468	473	19	.	.	PUNCT
admet-1468	474	1	acs	acs	PROPN
admet-1468	474	2	omega	omega	NOUN
admet-1468	474	3	4	4	NUM
admet-1468	474	4	(	(	PUNCT
admet-1468	474	5	2019	2019	NUM
admet-1468	474	6	)	)	PUNCT
admet-1468	474	7	835−841	835−841	NOUN
admet-1468	474	8	.	.	PUNCT
admet-1468	475	1	https://doi.org/10.1021/acsomega.8b02849	https://doi.org/10.1021/acsomega.8b02849	NOUN
admet-1468	475	2	[	[	X
admet-1468	475	3	37	37	NUM
admet-1468	475	4	]	]	X
admet-1468	475	5	j.a	j.a	PROPN
admet-1468	475	6	.	.	PROPN
admet-1468	475	7	badmus	badmus	PROPN
admet-1468	475	8	,	,	PUNCT
admet-1468	475	9	o.e	o.e	PROPN
admet-1468	475	10	.	.	PROPN
admet-1468	475	11	ekpo	ekpo	PROPN
admet-1468	475	12	,	,	PUNCT
admet-1468	475	13	a.a	a.a	PROPN
admet-1468	475	14	.	.	PROPN
admet-1468	475	15	hussein	hussein	PROPN
admet-1468	475	16	,	,	PUNCT
admet-1468	475	17	m.	m.	PROPN
admet-1468	475	18	meyer	meyer	PROPN
admet-1468	475	19	,	,	PUNCT
admet-1468	475	20	d.c	d.c	PROPN
admet-1468	475	21	.	.	PROPN
admet-1468	475	22	hiss	hiss	PROPN
admet-1468	475	23	.	.	PUNCT
admet-1468	476	1	cytotoxic	cytotoxic	ADJ
admet-1468	476	2	and	and	CCONJ
admet-1468	476	3	cell	cell	NOUN
admet-1468	476	4	cycle	cycle	NOUN
admet-1468	476	5	arrest	arrest	NOUN
admet-1468	476	6	properties	property	NOUN
admet-1468	476	7	of	of	ADP
admet-1468	476	8	two	two	NUM
admet-1468	476	9	steroidal	steroidal	NOUN
admet-1468	476	10	alkaloids	alkaloid	NOUN
admet-1468	476	11	isolated	isolate	VERB
admet-1468	476	12	from	from	ADP
admet-1468	476	13	holarrhena	holarrhena	ADJ
admet-1468	476	14	floribunda	floribunda	PROPN
admet-1468	476	15	(	(	PUNCT
admet-1468	476	16	g.	g.	PROPN
admet-1468	476	17	don	don	PROPN
admet-1468	476	18	)	)	PUNCT
admet-1468	477	1	t.	t.	PROPN
admet-1468	477	2	durand	durand	PROPN
admet-1468	477	3	&	&	CCONJ
admet-1468	477	4	schinz	schinz	PROPN
admet-1468	477	5	leaves	leaves	PROPN
admet-1468	477	6	.	.	PUNCT
admet-1468	478	1	bmc	bmc	PROPN
admet-1468	478	2	complement	complement	PROPN
admet-1468	478	3	.	.	PUNCT
admet-1468	479	1	altern	altern	NOUN
admet-1468	479	2	.	.	PUNCT
admet-1468	480	1	med	med	PROPN
admet-1468	480	2	.	.	PROPN
admet-1468	481	1	19	19	NUM
admet-1468	481	2	(	(	PUNCT
admet-1468	481	3	2019	2019	NUM
admet-1468	481	4	)	)	PUNCT
admet-1468	481	5	112	112	NUM
admet-1468	481	6	.	.	PUNCT
admet-1468	482	1	https://doi.org/10.1186/s12906-019-2521-9	https://doi.org/10.1186/s12906-019-2521-9	NOUN
admet-1468	483	1	[	[	X
admet-1468	483	2	38	38	NUM
admet-1468	483	3	]	]	X
admet-1468	483	4	d.h	d.h	PROPN
admet-1468	483	5	.	.	PROPN
admet-1468	483	6	dawood	dawood	PROPN
admet-1468	483	7	,	,	PUNCT
admet-1468	483	8	r.z	r.z	PROPN
admet-1468	483	9	.	.	PROPN
admet-1468	483	10	batran	batran	PROPN
admet-1468	483	11	,	,	PUNCT
admet-1468	483	12	t.a	t.a	PROPN
admet-1468	483	13	.	.	PROPN
admet-1468	483	14	farghaly	farghaly	PROPN
admet-1468	483	15	,	,	PUNCT
admet-1468	483	16	m.a	m.a	PROPN
admet-1468	483	17	.	.	PROPN
admet-1468	483	18	khedr	khedr	PROPN
admet-1468	483	19	,	,	PUNCT
admet-1468	483	20	m.m	m.m	PROPN
admet-1468	483	21	.	.	PROPN
admet-1468	483	22	abdulla	abdulla	PROPN
admet-1468	483	23	.	.	PUNCT
admet-1468	484	1	new	new	ADJ
admet-1468	484	2	coumarin	coumarin	NOUN
admet-1468	484	3	derivatives	derivative	NOUN
admet-1468	484	4	as	as	ADP
admet-1468	484	5	potent	potent	ADJ
admet-1468	484	6	selective	selective	ADJ
admet-1468	484	7	cox-2	cox-2	ADJ
admet-1468	484	8	inhibitors	inhibitor	NOUN
admet-1468	484	9	:	:	PUNCT
admet-1468	484	10	synthesis	synthesis	NOUN
admet-1468	484	11	,	,	PUNCT
admet-1468	484	12	anti	anti	ADJ
admet-1468	484	13	-	-	ADJ
admet-1468	484	14	inflammatory	inflammatory	ADJ
admet-1468	484	15	,	,	PUNCT
admet-1468	484	16	qsar	qsar	NOUN
admet-1468	484	17	,	,	PUNCT
admet-1468	484	18	and	and	CCONJ
admet-1468	484	19	molecular	molecular	ADJ
admet-1468	484	20	modeling	modeling	NOUN
admet-1468	484	21	studies	study	NOUN
admet-1468	484	22	.	.	PUNCT
admet-1468	485	1	arch	arch	NOUN
admet-1468	485	2	.	.	PUNCT
admet-1468	486	1	pharm	pharm	NOUN
admet-1468	486	2	.	.	PUNCT
admet-1468	487	1	(	(	PUNCT
admet-1468	487	2	weinheim	weinheim	PROPN
admet-1468	487	3	)	)	PUNCT
admet-1468	487	4	348	348	NUM
admet-1468	487	5	(	(	PUNCT
admet-1468	487	6	2015	2015	NUM
admet-1468	487	7	)	)	PUNCT
admet-1468	487	8	875	875	NUM
admet-1468	487	9	-	-	SYM
admet-1468	487	10	888	888	NUM
admet-1468	487	11	.	.	PUNCT
admet-1468	488	1	https://doi.org/10.1002/ardp.201500274	https://doi.org/10.1002/ardp.201500274	NOUN
admet-1468	488	2	[	[	X
admet-1468	488	3	39	39	NUM
admet-1468	488	4	]	]	SYM
admet-1468	488	5	f.m	f.m	PROPN
admet-1468	488	6	.	.	PROPN
admet-1468	488	7	aqlan	aqlan	NOUN
admet-1468	488	8	.	.	PUNCT
admet-1468	489	1	synthesis	synthesis	NOUN
admet-1468	489	2	,	,	PUNCT
admet-1468	489	3	admet	admet	NOUN
admet-1468	489	4	and	and	CCONJ
admet-1468	489	5	docking	dock	VERB
admet-1468	489	6	studies	study	NOUN
admet-1468	489	7	of	of	ADP
admet-1468	489	8	novel	novel	NOUN
admet-1468	489	9	pyrazoles	pyrazole	VERB
admet-1468	489	10	incorporating	incorporate	VERB
admet-1468	489	11	coumarin	coumarin	NOUN
admet-1468	489	12	moiety	moiety	NOUN
admet-1468	489	13	as	as	ADP
admet-1468	489	14	tyrosine	tyrosine	PROPN
admet-1468	489	15	kinase	kinase	PROPN
admet-1468	489	16	(	(	PUNCT
admet-1468	489	17	src	src	NOUN
admet-1468	489	18	)	)	PUNCT
admet-1468	489	19	inhibitors	inhibitor	NOUN
admet-1468	489	20	.	.	PUNCT
admet-1468	490	1	biointerface	biointerface	NOUN
admet-1468	490	2	res	re	NOUN
admet-1468	490	3	.	.	PUNCT
admet-1468	491	1	appl	appl	PROPN
admet-1468	491	2	.	.	PUNCT
admet-1468	492	1	chem	chem	PROPN
admet-1468	492	2	.	.	PUNCT
admet-1468	493	1	11(5	11(5	NUM
admet-1468	493	2	)	)	PUNCT
admet-1468	493	3	(	(	PUNCT
admet-1468	493	4	2021	2021	NUM
admet-1468	493	5	)	)	PUNCT
admet-1468	493	6	13706	13706	NUM
admet-1468	493	7	-	-	SYM
admet-1468	493	8	13714	13714	NUM
admet-1468	493	9	.	.	PUNCT
admet-1468	494	1	https://doi.org/10.33263/briac115.1370613714	https://doi.org/10.33263/briac115.1370613714	NUM
admet-1468	495	1	[	[	X
admet-1468	495	2	40	40	NUM
admet-1468	495	3	]	]	X
admet-1468	495	4	y.	y.	PROPN
admet-1468	495	5	han	han	PROPN
admet-1468	495	6	,	,	PUNCT
admet-1468	495	7	j.	j.	PROPN
admet-1468	495	8	zhang	zhang	PROPN
admet-1468	495	9	,	,	PUNCT
admet-1468	495	10	c.q	c.q	PROPN
admet-1468	495	11	.	.	PROPN
admet-1468	495	12	hu	hu	PROPN
admet-1468	495	13	,	,	PUNCT
admet-1468	495	14	x.	x.	PROPN
admet-1468	495	15	zhang	zhang	PROPN
admet-1468	495	16	,	,	PUNCT
admet-1468	495	17	b.	b.	PROPN
admet-1468	495	18	ma	ma	PROPN
admet-1468	495	19	,	,	PUNCT
admet-1468	495	20	p.	p.	PROPN
admet-1468	495	21	zhang	zhang	PROPN
admet-1468	495	22	.	.	PUNCT
admet-1468	496	1	in	in	ADP
admet-1468	496	2	silico	silico	NOUN
admet-1468	496	3	adme	adme	NOUN
admet-1468	496	4	and	and	CCONJ
admet-1468	496	5	toxicity	toxicity	NOUN
admet-1468	496	6	prediction	prediction	NOUN
admet-1468	496	7	of	of	ADP
admet-1468	496	8	ceftazidime	ceftazidime	NOUN
admet-1468	496	9	and	and	CCONJ
admet-1468	496	10	its	its	PRON
admet-1468	496	11	impurities	impurity	NOUN
admet-1468	496	12	.	.	PUNCT
admet-1468	497	1	front	front	ADJ
admet-1468	497	2	.	.	PUNCT
admet-1468	498	1	pharmacol	pharmacol	NOUN
admet-1468	498	2	.	.	PUNCT
admet-1468	499	1	10	10	NUM
admet-1468	499	2	(	(	PUNCT
admet-1468	499	3	2019	2019	NUM
admet-1468	499	4	)	)	PUNCT
admet-1468	499	5	434	434	NUM
admet-1468	499	6	.	.	PUNCT
admet-1468	500	1	https://doi.org/10.3389/fphar.2019.00434	https://doi.org/10.3389/fphar.2019.00434	NOUN
admet-1468	501	1	[	[	X
admet-1468	501	2	41	41	NUM
admet-1468	501	3	]	]	PUNCT
admet-1468	501	4	a.	a.	NOUN
admet-1468	501	5	daina	daina	PROPN
admet-1468	501	6	,	,	PUNCT
admet-1468	501	7	v.	v.	PROPN
admet-1468	501	8	zoete	zoete	PROPN
admet-1468	501	9	.	.	PUNCT
admet-1468	502	1	a	a	DET
admet-1468	502	2	boiled	boil	VERB
admet-1468	502	3	-	-	PUNCT
admet-1468	502	4	egg	egg	NOUN
admet-1468	502	5	to	to	PART
admet-1468	502	6	predict	predict	VERB
admet-1468	502	7	gastrointestinal	gastrointestinal	ADJ
admet-1468	502	8	absorption	absorption	NOUN
admet-1468	502	9	and	and	CCONJ
admet-1468	502	10	brain	brain	NOUN
admet-1468	502	11	penetration	penetration	NOUN
admet-1468	502	12	of	of	ADP
admet-1468	502	13	small	small	ADJ
admet-1468	502	14	molecules	molecule	NOUN
admet-1468	502	15	.	.	PUNCT
admet-1468	503	1	chem	chem	NOUN
admet-1468	503	2	.	.	PUNCT
admet-1468	504	1	med	med	PROPN
admet-1468	504	2	.	.	PUNCT
admet-1468	504	3	chem	chem	PROPN
admet-1468	504	4	.	.	PUNCT
admet-1468	505	1	11	11	NUM
admet-1468	505	2	(	(	PUNCT
admet-1468	505	3	2016	2016	NUM
admet-1468	505	4	)	)	PUNCT
admet-1468	505	5	1117	1117	NUM
admet-1468	505	6	-	-	SYM
admet-1468	505	7	1121	1121	NUM
admet-1468	505	8	.	.	PUNCT
admet-1468	506	1	https://doi.org/10.1002/cmdc.201600182	https://doi.org/10.1002/cmdc.201600182	PROPN
admet-1468	507	1	[	[	X
admet-1468	507	2	42	42	NUM
admet-1468	507	3	]	]	X
admet-1468	507	4	g.r	g.r	PROPN
admet-1468	507	5	.	.	PROPN
admet-1468	507	6	bickerton	bickerton	PROPN
admet-1468	507	7	,	,	PUNCT
admet-1468	507	8	g.v	g.v	PROPN
admet-1468	507	9	.	.	PROPN
admet-1468	507	10	paolini	paolini	PROPN
admet-1468	507	11	,	,	PUNCT
admet-1468	507	12	j.	j.	PROPN
admet-1468	507	13	besnard	besnard	PROPN
admet-1468	507	14	,	,	PUNCT
admet-1468	507	15	s.	s.	PROPN
admet-1468	507	16	muresan	muresan	PROPN
admet-1468	507	17	,	,	PUNCT
admet-1468	507	18	a.l	a.l	PROPN
admet-1468	507	19	.	.	PROPN
admet-1468	507	20	hopkins	hopkins	PROPN
admet-1468	507	21	.	.	PUNCT
admet-1468	508	1	quantifying	quantify	VERB
admet-1468	508	2	the	the	DET
admet-1468	508	3	chemical	chemical	NOUN
admet-1468	508	4	beauty	beauty	NOUN
admet-1468	508	5	of	of	ADP
admet-1468	508	6	drugs	drug	NOUN
admet-1468	508	7	.	.	PUNCT
admet-1468	509	1	nat	nat	PROPN
admet-1468	509	2	.	.	PUNCT
admet-1468	510	1	chem	chem	PROPN
admet-1468	510	2	.	.	PUNCT
admet-1468	511	1	4	4	NUM
admet-1468	511	2	(	(	PUNCT
admet-1468	511	3	2012	2012	NUM
admet-1468	511	4	)	)	PUNCT
admet-1468	511	5	90	90	NUM
admet-1468	511	6	-	-	SYM
admet-1468	511	7	98	98	NUM
admet-1468	511	8	.	.	PUNCT
admet-1468	512	1	https://doi.org/10.1038%2fnchem.1243	https://doi.org/10.1038%2fnchem.1243	NOUN
admet-1468	513	1	[	[	X
admet-1468	513	2	43	43	NUM
admet-1468	513	3	]	]	X
admet-1468	513	4	j.	j.	PROPN
admet-1468	513	5	barrios	barrios	PROPN
admet-1468	513	6	-	-	PUNCT
admet-1468	513	7	gonzález	gonzález	PROPN
admet-1468	513	8	,	,	PUNCT
admet-1468	513	9	a.	a.	NOUN
admet-1468	513	10	mejýa	mejýa	PROPN
admet-1468	513	11	.	.	PUNCT
admet-1468	514	1	production	production	NOUN
admet-1468	514	2	of	of	ADP
admet-1468	514	3	antibiotics	antibiotic	NOUN
admet-1468	514	4	and	and	CCONJ
admet-1468	514	5	other	other	ADJ
admet-1468	514	6	commercially	commercially	ADV
admet-1468	514	7	valuable	valuable	ADJ
admet-1468	514	8	secondary	secondary	ADJ
admet-1468	514	9	metabolites	metabolite	NOUN
admet-1468	514	10	.	.	PUNCT
admet-1468	515	1	in	in	ADP
admet-1468	515	2	:	:	PUNCT
admet-1468	515	3	current	current	ADJ
admet-1468	515	4	developments	development	NOUN
admet-1468	515	5	in	in	ADP
admet-1468	515	6	solid	solid	ADJ
admet-1468	515	7	-	-	PUNCT
admet-1468	515	8	state	state	NOUN
admet-1468	515	9	fermentation	fermentation	NOUN
admet-1468	515	10	a.	a.	NOUN
admet-1468	515	11	pandey	pandey	PROPN
admet-1468	515	12	,	,	PUNCT
admet-1468	515	13	c.	c.	PROPN
admet-1468	515	14	r.	r.	PROPN
admet-1468	515	15	soccol	soccol	PROPN
admet-1468	515	16	,	,	PUNCT
admet-1468	515	17	c.	c.	PROPN
admet-1468	515	18	larroche	larroche	PROPN
admet-1468	515	19	.	.	PUNCT
admet-1468	516	1	(	(	PUNCT
admet-1468	516	2	eds	ed	NOUN
admet-1468	516	3	)	)	PUNCT
admet-1468	516	4	.	.	PUNCT
admet-1468	516	5	,	,	PUNCT
admet-1468	516	6	springer	springer	NOUN
admet-1468	516	7	,	,	PUNCT
admet-1468	516	8	new	new	PROPN
admet-1468	516	9	york	york	PROPN
admet-1468	516	10	,	,	PUNCT
admet-1468	516	11	ny	ny	PROPN
admet-1468	516	12	,	,	PUNCT
admet-1468	516	13	usa	usa	PROPN
admet-1468	516	14	,	,	PUNCT
admet-1468	516	15	2008	2008	NUM
admet-1468	516	16	,	,	PUNCT
admet-1468	516	17	302–336	302–336	NUM
admet-1468	516	18	.	.	PUNCT
admet-1468	517	1	https://doi.org/10.1007/978-0-387-75213-6_14	https://doi.org/10.1007/978-0-387-75213-6_14	NOUN
admet-1468	518	1	[	[	X
admet-1468	518	2	44	44	NUM
admet-1468	518	3	]	]	PUNCT
admet-1468	518	4	d.	d.	PROPN
admet-1468	518	5	xia	xia	PROPN
admet-1468	518	6	,	,	PUNCT
admet-1468	518	7	x.	x.	PROPN
admet-1468	518	8	yang	yang	PROPN
admet-1468	518	9	,	,	PUNCT
admet-1468	518	10	w.	w.	PROPN
admet-1468	518	11	liu	liu	PROPN
admet-1468	518	12	,	,	PUNCT
admet-1468	518	13	f.	f.	PROPN
admet-1468	518	14	shen	shen	PROPN
admet-1468	518	15	,	,	PUNCT
admet-1468	518	16	j.	j.	PROPN
admet-1468	518	17	pan	pan	PROPN
admet-1468	518	18	,	,	PUNCT
admet-1468	518	19	y.	y.	PROPN
admet-1468	518	20	lin	lin	PROPN
admet-1468	518	21	,	,	PUNCT
admet-1468	518	22	n.	n.	PROPN
admet-1468	518	23	du	du	PROPN
admet-1468	518	24	,	,	PUNCT
admet-1468	518	25	y.	y.	PROPN
admet-1468	518	26	sun	sun	PROPN
admet-1468	518	27	,	,	PUNCT
admet-1468	518	28	x.	x.	NOUN
admet-1468	518	29	xi	xi	PROPN
admet-1468	518	30	.	.	PUNCT
admet-1468	519	1	over	over	ADP
admet-1468	519	2	-	-	PUNCT
admet-1468	519	3	expression	expression	NOUN
admet-1468	519	4	of	of	ADP
admet-1468	519	5	chaf1a	chaf1a	PROPN
admet-1468	519	6	in	in	ADP
admet-1468	519	7	epithelial	epithelial	ADJ
admet-1468	519	8	ovarian	ovarian	ADJ
admet-1468	519	9	cancer	cancer	NOUN
admet-1468	519	10	can	can	AUX
admet-1468	519	11	promote	promote	VERB
admet-1468	519	12	cell	cell	NOUN
admet-1468	519	13	proliferation	proliferation	NOUN
admet-1468	519	14	and	and	CCONJ
admet-1468	519	15	inhibit	inhibit	VERB
admet-1468	519	16	cell	cell	NOUN
admet-1468	519	17	apoptosis	apoptosis	NOUN
admet-1468	519	18	.	.	PUNCT
admet-1468	520	1	biochem	biochem	PROPN
admet-1468	520	2	.	.	PUNCT
admet-1468	521	1	biophys	biophy	NOUN
admet-1468	521	2	.	.	PUNCT
admet-1468	522	1	res	re	NOUN
admet-1468	522	2	.	.	PUNCT
admet-1468	523	1	commun	commun	PROPN
admet-1468	523	2	.	.	PUNCT
admet-1468	524	1	486(1	486(1	NUM
admet-1468	524	2	)	)	PUNCT
admet-1468	524	3	(	(	PUNCT
admet-1468	524	4	2017	2017	NUM
admet-1468	524	5	)	)	PUNCT
admet-1468	524	6	191	191	NUM
admet-1468	524	7	-	-	SYM
admet-1468	524	8	197	197	NUM
admet-1468	524	9	.	.	PUNCT
admet-1468	525	1	https://doi.org/10.1016/j.bbrc.2017.03.026	https://doi.org/10.1016/j.bbrc.2017.03.026	PROPN
admet-1468	525	2	©	©	ADP
admet-1468	525	3	2022	2022	NUM
admet-1468	525	4	by	by	ADP
admet-1468	525	5	the	the	DET
admet-1468	525	6	authors	author	NOUN
admet-1468	525	7	;	;	PUNCT
admet-1468	525	8	licensee	licensee	PROPN
admet-1468	525	9	iapc	iapc	PROPN
admet-1468	525	10	,	,	PUNCT
admet-1468	525	11	zagreb	zagreb	PROPN
admet-1468	525	12	,	,	PUNCT
admet-1468	525	13	croatia	croatia	PROPN
admet-1468	525	14	.	.	PUNCT
admet-1468	526	1	this	this	DET
admet-1468	526	2	article	article	NOUN
admet-1468	526	3	is	be	AUX
admet-1468	526	4	an	an	DET
admet-1468	526	5	open	open	ADJ
admet-1468	526	6	-	-	PUNCT
admet-1468	526	7	access	access	NOUN
admet-1468	526	8	article	article	NOUN
admet-1468	526	9	distributed	distribute	VERB
admet-1468	526	10	under	under	ADP
admet-1468	526	11	the	the	DET
admet-1468	526	12	terms	term	NOUN
admet-1468	526	13	and	and	CCONJ
admet-1468	526	14	conditions	condition	NOUN
admet-1468	526	15	of	of	ADP
admet-1468	526	16	the	the	DET
admet-1468	526	17	creative	creative	ADJ
admet-1468	526	18	commons	common	NOUN
admet-1468	526	19	attribution	attribution	NOUN
admet-1468	526	20	license	license	NOUN
admet-1468	526	21	(	(	PUNCT
admet-1468	526	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	NOUN
admet-1468	526	23	)	)	PUNCT
admet-1468	526	24	https://doi.org/10.1002/jcp.27411	https://doi.org/10.1002/jcp.27411	PROPN
admet-1468	526	25	https://doi.org/10.1021/acsomega.8b02849	https://doi.org/10.1021/acsomega.8b02849	NOUN
admet-1468	526	26	https://doi.org/10.1186/s12906-019-2521-9	https://doi.org/10.1186/s12906-019-2521-9	NUM
admet-1468	526	27	https://doi.org/10.1002/ardp.201500274	https://doi.org/10.1002/ardp.201500274	NOUN
admet-1468	526	28	https://doi.org/10.33263/briac115.1370613714	https://doi.org/10.33263/briac115.1370613714	NUM
admet-1468	526	29	https://doi.org/10.3389/fphar.2019.00434	https://doi.org/10.3389/fphar.2019.00434	PROPN
admet-1468	526	30	https://doi.org/10.1002/cmdc.201600182	https://doi.org/10.1002/cmdc.201600182	NOUN
admet-1468	526	31	https://doi.org/10.1038%2fnchem.1243	https://doi.org/10.1038%2fnchem.1243	NOUN
admet-1468	526	32	https://doi.org/10.1007/978-0-387-75213-6_14	https://doi.org/10.1007/978-0-387-75213-6_14	NOUN
admet-1468	526	33	https://doi.org/10.1016/j.bbrc.2017.03.026	https://doi.org/10.1016/j.bbrc.2017.03.026	NOUN
admet-1468	526	34	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	NOUN