id	sid	tid	token	lemma	pos
admet-1586	1	1	dissolution	dissolution	NOUN
admet-1586	1	2	-	-	PUNCT
admet-1586	1	3	permeation	permeation	NOUN
admet-1586	1	4	of	of	ADP
admet-1586	1	5	hot	hot	ADJ
admet-1586	1	6	-	-	PUNCT
admet-1586	1	7	melt	melt	NOUN
admet-1586	1	8	extruded	extrude	VERB
admet-1586	1	9	amorphous	amorphous	ADJ
admet-1586	1	10	solid	solid	ADJ
admet-1586	1	11	dispersion	dispersion	NOUN
admet-1586	1	12	comprising	comprise	VERB
admet-1586	1	13	an	an	DET
admet-1586	1	14	experimental	experimental	ADJ
admet-1586	1	15	grade	grade	NOUN
admet-1586	1	16	of	of	ADP
admet-1586	1	17	hpmcas	hpmcas	PROPN
admet-1586	1	18	doi	doi	PROPN
admet-1586	1	19	:	:	PUNCT
admet-1586	1	20	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	NOUN
admet-1586	1	21	373	373	NUM
admet-1586	1	22	admet	admet	X
admet-1586	1	23	&	&	CCONJ
admet-1586	1	24	dmpk	dmpk	PROPN
admet-1586	1	25	11(3	11(3	NUM
admet-1586	1	26	)	)	PUNCT
admet-1586	1	27	(	(	PUNCT
admet-1586	1	28	2023	2023	NUM
admet-1586	1	29	)	)	PUNCT
admet-1586	1	30	373	373	NUM
admet-1586	1	31	-	-	SYM
admet-1586	1	32	385	385	NUM
admet-1586	1	33	;	;	PUNCT
admet-1586	1	34	doi	doi	NOUN
admet-1586	1	35	:	:	PUNCT
admet-1586	1	36	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	NOUN
admet-1586	1	37	open	open	ADJ
admet-1586	1	38	access	access	NOUN
admet-1586	1	39	:	:	PUNCT
admet-1586	1	40	issn	issn	PROPN
admet-1586	1	41	:	:	PUNCT
admet-1586	1	42	1848	1848	NUM
admet-1586	1	43	-	-	SYM
admet-1586	1	44	7718	7718	NUM
admet-1586	1	45	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-1586	1	46	original	original	ADJ
admet-1586	1	47	scientific	scientific	ADJ
admet-1586	1	48	paper	paper	NOUN
admet-1586	1	49	dissolution	dissolution	NOUN
admet-1586	1	50	-	-	PUNCT
admet-1586	1	51	permeation	permeation	NOUN
admet-1586	1	52	of	of	ADP
admet-1586	1	53	hot	hot	ADJ
admet-1586	1	54	-	-	PUNCT
admet-1586	1	55	melt	melt	NOUN
admet-1586	1	56	extruded	extrude	VERB
admet-1586	1	57	amorphous	amorphous	ADJ
admet-1586	1	58	solid	solid	ADJ
admet-1586	1	59	dispersion	dispersion	NOUN
admet-1586	1	60	comprising	comprise	VERB
admet-1586	1	61	an	an	DET
admet-1586	1	62	experimental	experimental	ADJ
admet-1586	1	63	grade	grade	NOUN
admet-1586	1	64	of	of	ADP
admet-1586	1	65	hpmcas	hpmcas	PROPN
admet-1586	1	66	hironori	hironori	PROPN
admet-1586	1	67	tanaka1	tanaka1	PROPN
admet-1586	1	68	,	,	PUNCT
admet-1586	1	69	tetsuya	tetsuya	PROPN
admet-1586	1	70	miyano2	miyano2	PROPN
admet-1586	1	71	and	and	CCONJ
admet-1586	1	72	hiroshi	hiroshi	PROPN
admet-1586	1	73	ueda3	ueda3	PROPN
admet-1586	1	74	,	,	PUNCT
admet-1586	1	75	*	*	PROPN
admet-1586	1	76	1formulation	1formulation	NUM
admet-1586	1	77	r&d	r&d	NOUN
admet-1586	1	78	laboratory	laboratory	NOUN
admet-1586	1	79	,	,	PUNCT
admet-1586	1	80	shionogi	shionogi	PROPN
admet-1586	1	81	&	&	CCONJ
admet-1586	1	82	co.	co.	PROPN
admet-1586	1	83	,	,	PUNCT
admet-1586	1	84	ltd	ltd	PROPN
admet-1586	1	85	.	.	PROPN
admet-1586	1	86	,	,	PUNCT
admet-1586	1	87	hyogo	hyogo	VERB
admet-1586	1	88	660	660	NUM
admet-1586	1	89	-	-	SYM
admet-1586	1	90	0813	0813	NUM
admet-1586	1	91	,	,	PUNCT
admet-1586	1	92	japan	japan	PROPN
admet-1586	1	93	2laboratory	2laboratory	NUM
admet-1586	1	94	for	for	ADP
admet-1586	1	95	medicinal	medicinal	ADJ
admet-1586	1	96	chemistry	chemistry	NOUN
admet-1586	1	97	research	research	NOUN
admet-1586	1	98	,	,	PUNCT
admet-1586	1	99	shionogi	shionogi	PROPN
admet-1586	1	100	&	&	CCONJ
admet-1586	1	101	co.	co.	PROPN
admet-1586	1	102	,	,	PUNCT
admet-1586	1	103	ltd	ltd	PROPN
admet-1586	1	104	.	.	PROPN
admet-1586	1	105	,	,	PUNCT
admet-1586	1	106	osaka	osaka	PROPN
admet-1586	1	107	,	,	PUNCT
admet-1586	1	108	561	561	NUM
admet-1586	1	109	-	-	SYM
admet-1586	1	110	0825	0825	NUM
admet-1586	1	111	,	,	PUNCT
admet-1586	1	112	japan	japan	PROPN
admet-1586	1	113	3analysis	3analysis	NUM
admet-1586	1	114	and	and	CCONJ
admet-1586	1	115	evaluation	evaluation	NOUN
admet-1586	1	116	laboratory	laboratory	NOUN
admet-1586	1	117	,	,	PUNCT
admet-1586	1	118	shionogi	shionogi	PROPN
admet-1586	1	119	&	&	CCONJ
admet-1586	1	120	co.	co.	PROPN
admet-1586	1	121	,	,	PUNCT
admet-1586	1	122	ltd	ltd	PROPN
admet-1586	1	123	.	.	PROPN
admet-1586	1	124	,	,	PUNCT
admet-1586	1	125	osaka	osaka	PROPN
admet-1586	1	126	,	,	PUNCT
admet-1586	1	127	561	561	NUM
admet-1586	1	128	-	-	SYM
admet-1586	1	129	0825	0825	NUM
admet-1586	1	130	,	,	PUNCT
admet-1586	1	131	japan	japan	PROPN
admet-1586	1	132	*	*	PUNCT
admet-1586	1	133	corresponding	correspond	VERB
admet-1586	1	134	author	author	NOUN
admet-1586	1	135	:	:	PUNCT
admet-1586	1	136	e	e	NOUN
admet-1586	1	137	-	-	NOUN
admet-1586	1	138	mail	mail	NOUN
admet-1586	1	139	:	:	PUNCT
admet-1586	1	140	:	:	PUNCT
admet-1586	1	141	hiroshi.ueda@shionogi.co.jp	hiroshi.ueda@shionogi.co.jp	NUM
admet-1586	1	142	;	;	PUNCT
admet-1586	1	143	tel	tel	PROPN
admet-1586	1	144	.	.	PROPN
admet-1586	1	145	:	:	PUNCT
admet-1586	2	1	+81	+81	NUM
admet-1586	2	2	-	-	PUNCT
admet-1586	2	3	6	6	NUM
admet-1586	2	4	-	-	PUNCT
admet-1586	2	5	6331	6331	NUM
admet-1586	2	6	-	-	SYM
admet-1586	2	7	5747	5747	NUM
admet-1586	2	8	;	;	PUNCT
admet-1586	2	9	fax	fax	NOUN
admet-1586	2	10	:	:	PUNCT
admet-1586	2	11	+81	+81	ADJ
admet-1586	2	12	-	-	PUNCT
admet-1586	2	13	6	6	NUM
admet-1586	2	14	-	-	PUNCT
admet-1586	2	15	6332	6332	NUM
admet-1586	2	16	-	-	PUNCT
admet-1586	2	17	6385	6385	NUM
admet-1586	2	18	received	receive	VERB
admet-1586	2	19	:	:	PUNCT
admet-1586	2	20	november	november	PROPN
admet-1586	2	21	4	4	NUM
admet-1586	2	22	,	,	PUNCT
admet-1586	2	23	2022	2022	NUM
admet-1586	2	24	;	;	PUNCT
admet-1586	2	25	revised	revise	VERB
admet-1586	2	26	:	:	PUNCT
admet-1586	2	27	july	july	PROPN
admet-1586	2	28	20	20	NUM
admet-1586	2	29	,	,	PUNCT
admet-1586	2	30	2023	2023	NUM
admet-1586	2	31	;	;	PUNCT
admet-1586	2	32	published	publish	VERB
admet-1586	2	33	:	:	PUNCT
admet-1586	2	34	july	july	PROPN
admet-1586	2	35	22,2023	22,2023	NUM
admet-1586	2	36	abstract	abstract	ADJ
admet-1586	2	37	background	background	NOUN
admet-1586	2	38	and	and	CCONJ
admet-1586	2	39	purpose	purpose	NOUN
admet-1586	2	40	:	:	PUNCT
admet-1586	2	41	physicochemical	physicochemical	ADJ
admet-1586	2	42	properties	property	NOUN
admet-1586	2	43	of	of	ADP
admet-1586	2	44	an	an	DET
admet-1586	2	45	amorphous	amorphous	ADJ
admet-1586	2	46	solid	solid	ADJ
admet-1586	2	47	dispersion	dispersion	NOUN
admet-1586	2	48	(	(	PUNCT
admet-1586	2	49	asd	asd	NOUN
admet-1586	2	50	)	)	PUNCT
admet-1586	2	51	comprising	comprise	VERB
admet-1586	2	52	an	an	DET
admet-1586	2	53	experimental	experimental	ADJ
admet-1586	2	54	grade	grade	NOUN
admet-1586	2	55	of	of	ADP
admet-1586	2	56	hydroxypropyl	hydroxypropyl	ADJ
admet-1586	2	57	methylcellulose	methylcellulose	NOUN
admet-1586	2	58	acetate	acetate	NOUN
admet-1586	2	59	succinate	succinate	NOUN
admet-1586	2	60	(	(	PUNCT
admet-1586	2	61	hpmcas	hpmcas	NOUN
admet-1586	2	62	-	-	PUNCT
admet-1586	2	63	mx	mx	NOUN
admet-1586	2	64	)	)	PUNCT
admet-1586	2	65	with	with	ADP
admet-1586	2	66	lower	low	ADJ
admet-1586	2	67	glass	glass	NOUN
admet-1586	2	68	transition	transition	NOUN
admet-1586	2	69	temperature	temperature	NOUN
admet-1586	2	70	have	have	AUX
admet-1586	2	71	been	be	AUX
admet-1586	2	72	previously	previously	ADV
admet-1586	2	73	investigated	investigate	VERB
admet-1586	2	74	.	.	PUNCT
admet-1586	3	1	this	this	DET
admet-1586	3	2	study	study	NOUN
admet-1586	3	3	aimed	aim	VERB
admet-1586	3	4	to	to	PART
admet-1586	3	5	evaluate	evaluate	VERB
admet-1586	3	6	applicability	applicability	NOUN
admet-1586	3	7	of	of	ADP
admet-1586	3	8	hpmcas	hpmcas	NOUN
admet-1586	3	9	-	-	PUNCT
admet-1586	3	10	mx	mx	NOUN
admet-1586	3	11	to	to	ADP
admet-1586	3	12	hot	hot	ADJ
admet-1586	3	13	-	-	PUNCT
admet-1586	3	14	melt	melt	NOUN
admet-1586	3	15	extrusion	extrusion	NOUN
admet-1586	3	16	(	(	PUNCT
admet-1586	3	17	hme	hme	NOUN
admet-1586	3	18	)	)	PUNCT
admet-1586	3	19	and	and	CCONJ
admet-1586	3	20	dissolution	dissolution	NOUN
admet-1586	3	21	-	-	PUNCT
admet-1586	3	22	permeation	permeation	NOUN
admet-1586	3	23	performance	performance	NOUN
admet-1586	3	24	of	of	ADP
admet-1586	3	25	prepared	prepared	ADJ
admet-1586	3	26	asds	asds	NOUN
admet-1586	3	27	using	use	VERB
admet-1586	3	28	microflux	microflux	NOUN
admet-1586	3	29	.	.	PUNCT
admet-1586	4	1	review	review	NOUN
admet-1586	4	2	approach	approach	NOUN
admet-1586	4	3	:	:	PUNCT
admet-1586	4	4	a	a	DET
admet-1586	4	5	physical	physical	ADJ
admet-1586	4	6	mixture	mixture	NOUN
admet-1586	4	7	of	of	ADP
admet-1586	4	8	indomethacin	indomethacin	PROPN
admet-1586	4	9	(	(	PUNCT
admet-1586	4	10	imc	imc	PROPN
admet-1586	4	11	)	)	PUNCT
admet-1586	4	12	and	and	CCONJ
admet-1586	4	13	hpmcas	hpmca	NOUN
admet-1586	4	14	-	-	PUNCT
admet-1586	4	15	mx	mx	NOUN
admet-1586	4	16	or	or	CCONJ
admet-1586	4	17	-mg	-mg	ADJ
admet-1586	4	18	(	(	PUNCT
admet-1586	4	19	a	a	DET
admet-1586	4	20	commercial	commercial	ADJ
admet-1586	4	21	grade	grade	NOUN
admet-1586	4	22	with	with	ADP
admet-1586	4	23	higher	high	ADJ
admet-1586	4	24	transition	transition	NOUN
admet-1586	4	25	temperature	temperature	NOUN
admet-1586	4	26	)	)	PUNCT
admet-1586	4	27	at	at	ADP
admet-1586	4	28	20:80	20:80	NUM
admet-1586	4	29	weight	weight	NOUN
admet-1586	4	30	ratio	ratio	NOUN
admet-1586	4	31	was	be	AUX
admet-1586	4	32	hot	hot	ADJ
admet-1586	4	33	-	-	PUNCT
admet-1586	4	34	melt	melt	NOUN
admet-1586	4	35	extruded	extrude	VERB
admet-1586	4	36	to	to	PART
admet-1586	4	37	prepare	prepare	VERB
admet-1586	4	38	an	an	DET
admet-1586	4	39	asd	asd	NOUN
admet-1586	4	40	(	(	PUNCT
admet-1586	4	41	imc	imc	PROPN
admet-1586	4	42	-	-	PUNCT
admet-1586	4	43	mx	mx	PROPN
admet-1586	4	44	and	and	CCONJ
admet-1586	4	45	imc	imc	PROPN
admet-1586	4	46	-	-	PUNCT
admet-1586	4	47	mg	mg	PROPN
admet-1586	4	48	,	,	PUNCT
admet-1586	4	49	respectively	respectively	ADV
admet-1586	4	50	)	)	PUNCT
admet-1586	4	51	.	.	PUNCT
admet-1586	5	1	the	the	DET
admet-1586	5	2	dissolution	dissolution	NOUN
admet-1586	5	3	-	-	PUNCT
admet-1586	5	4	permeation	permeation	NOUN
admet-1586	5	5	performance	performance	NOUN
admet-1586	5	6	and	and	CCONJ
admet-1586	5	7	the	the	DET
admet-1586	5	8	stability	stability	NOUN
admet-1586	5	9	of	of	ADP
admet-1586	5	10	the	the	DET
admet-1586	5	11	asds	asds	NOUN
admet-1586	5	12	were	be	AUX
admet-1586	5	13	measured	measure	VERB
admet-1586	5	14	.	.	PUNCT
admet-1586	6	1	key	key	ADJ
admet-1586	6	2	results	result	NOUN
admet-1586	6	3	:	:	PUNCT
admet-1586	6	4	a	a	DET
admet-1586	6	5	torque	torque	NOUN
admet-1586	6	6	reduction	reduction	NOUN
admet-1586	6	7	at	at	ADP
admet-1586	6	8	120	120	NUM
admet-1586	6	9	°	°	NOUN
admet-1586	6	10	c	c	NOUN
admet-1586	6	11	implied	imply	VERB
admet-1586	6	12	that	that	SCONJ
admet-1586	6	13	imc	imc	PROPN
admet-1586	6	14	-	-	PUNCT
admet-1586	6	15	mx	mx	PROPN
admet-1586	6	16	transformed	transform	VERB
admet-1586	6	17	into	into	ADP
admet-1586	6	18	an	an	DET
admet-1586	6	19	amorphous	amorphous	ADJ
admet-1586	6	20	state	state	NOUN
admet-1586	6	21	at	at	ADP
admet-1586	6	22	this	this	DET
admet-1586	6	23	temperature	temperature	NOUN
admet-1586	6	24	,	,	PUNCT
admet-1586	6	25	but	but	CCONJ
admet-1586	6	26	imc	imc	PROPN
admet-1586	6	27	-	-	PUNCT
admet-1586	6	28	mg	mg	PROPN
admet-1586	6	29	required	require	VERB
admet-1586	6	30	around	around	ADP
admet-1586	6	31	170	170	NUM
admet-1586	6	32	°	°	NOUN
admet-1586	6	33	c	c	X
admet-1586	6	34	.	.	PUNCT
admet-1586	7	1	this	this	DET
admet-1586	7	2	result	result	NOUN
admet-1586	7	3	was	be	AUX
admet-1586	7	4	supported	support	VERB
admet-1586	7	5	by	by	ADP
admet-1586	7	6	raman	raman	NOUN
admet-1586	7	7	mapping	mapping	NOUN
admet-1586	7	8	of	of	ADP
admet-1586	7	9	the	the	DET
admet-1586	7	10	the	the	DET
admet-1586	7	11	hme	hme	NOUN
admet-1586	7	12	samples	sample	NOUN
admet-1586	7	13	.	.	PUNCT
admet-1586	8	1	imc	imc	PROPN
admet-1586	8	2	-	-	PUNCT
admet-1586	8	3	mg	mg	PROPN
admet-1586	8	4	and	and	CCONJ
admet-1586	8	5	imc	imc	PROPN
admet-1586	8	6	-	-	PUNCT
admet-1586	8	7	mx	mx	PROPN
admet-1586	8	8	remained	remain	VERB
admet-1586	8	9	in	in	ADP
admet-1586	8	10	an	an	DET
admet-1586	8	11	amorphous	amorphous	ADJ
admet-1586	8	12	state	state	NOUN
admet-1586	8	13	at	at	ADP
admet-1586	8	14	40	40	NUM
admet-1586	8	15	°	°	ADP
admet-1586	8	16	c	c	NOUN
admet-1586	8	17	for	for	ADP
admet-1586	8	18	three	three	NUM
admet-1586	8	19	months	month	NOUN
admet-1586	8	20	.	.	PUNCT
admet-1586	9	1	the	the	DET
admet-1586	9	2	initial	initial	ADJ
admet-1586	9	3	dissolution	dissolution	NOUN
admet-1586	9	4	rate	rate	NOUN
admet-1586	9	5	and	and	CCONJ
admet-1586	9	6	solubility	solubility	NOUN
admet-1586	9	7	of	of	ADP
admet-1586	9	8	the	the	DET
admet-1586	9	9	asds	asds	NOUN
admet-1586	9	10	were	be	AUX
admet-1586	9	11	higher	high	ADJ
admet-1586	9	12	than	than	ADP
admet-1586	9	13	that	that	PRON
admet-1586	9	14	of	of	ADP
admet-1586	9	15	crystalline	crystalline	PROPN
admet-1586	9	16	imc	imc	PROPN
admet-1586	9	17	.	.	PUNCT
admet-1586	10	1	the	the	DET
admet-1586	10	2	apparent	apparent	ADJ
admet-1586	10	3	permeability	permeability	NOUN
admet-1586	10	4	of	of	ADP
admet-1586	10	5	imc	imc	PROPN
admet-1586	10	6	from	from	ADP
admet-1586	10	7	imc	imc	PROPN
admet-1586	10	8	-	-	PUNCT
admet-1586	10	9	mx	mx	PROPN
admet-1586	10	10	and	and	CCONJ
admet-1586	10	11	imc	imc	PROPN
admet-1586	10	12	-	-	PUNCT
admet-1586	10	13	mg	mg	PROPN
admet-1586	10	14	was	be	AUX
admet-1586	10	15	comparable	comparable	ADJ
admet-1586	10	16	but	but	CCONJ
admet-1586	10	17	was	be	AUX
admet-1586	10	18	approximately	approximately	ADV
admet-1586	10	19	two	two	NUM
admet-1586	10	20	-	-	PUNCT
admet-1586	10	21	fold	fold	VERB
admet-1586	10	22	higher	high	ADJ
admet-1586	10	23	than	than	ADP
admet-1586	10	24	that	that	PRON
admet-1586	10	25	from	from	ADP
admet-1586	10	26	crystalline	crystalline	PROPN
admet-1586	10	27	imc	imc	PROPN
admet-1586	10	28	.	.	PUNCT
admet-1586	11	1	conclusion	conclusion	NOUN
admet-1586	11	2	:	:	PUNCT
admet-1586	11	3	hpmcas	hpmcas	PROPN
admet-1586	11	4	-	-	PUNCT
admet-1586	11	5	mx	mx	NOUN
admet-1586	11	6	enabled	enable	VERB
admet-1586	11	7	hme	hme	NOUN
admet-1586	11	8	process	process	NOUN
admet-1586	11	9	at	at	ADP
admet-1586	11	10	a	a	DET
admet-1586	11	11	lower	low	ADJ
admet-1586	11	12	temperature	temperature	NOUN
admet-1586	11	13	and	and	CCONJ
admet-1586	11	14	improved	improve	VERB
admet-1586	11	15	the	the	DET
admet-1586	11	16	dissolution	dissolution	NOUN
admet-1586	11	17	-	-	PUNCT
admet-1586	11	18	permeation	permeation	NOUN
admet-1586	11	19	performance	performance	NOUN
admet-1586	11	20	of	of	ADP
admet-1586	11	21	indomethacin	indomethacin	NOUN
admet-1586	11	22	.	.	PUNCT
admet-1586	12	1	©	©	PROPN
admet-1586	12	2	2023	2023	NUM
admet-1586	12	3	by	by	ADP
admet-1586	12	4	the	the	DET
admet-1586	12	5	authors	author	NOUN
admet-1586	12	6	.	.	PUNCT
admet-1586	13	1	this	this	DET
admet-1586	13	2	article	article	NOUN
admet-1586	13	3	is	be	AUX
admet-1586	13	4	an	an	DET
admet-1586	13	5	open	open	ADJ
admet-1586	13	6	-	-	PUNCT
admet-1586	13	7	access	access	NOUN
admet-1586	13	8	article	article	NOUN
admet-1586	13	9	distributed	distribute	VERB
admet-1586	13	10	under	under	ADP
admet-1586	13	11	the	the	DET
admet-1586	13	12	terms	term	NOUN
admet-1586	13	13	and	and	CCONJ
admet-1586	13	14	conditions	condition	NOUN
admet-1586	13	15	of	of	ADP
admet-1586	13	16	the	the	DET
admet-1586	13	17	creative	creative	ADJ
admet-1586	13	18	commons	common	NOUN
admet-1586	13	19	attribution	attribution	NOUN
admet-1586	13	20	license	license	NOUN
admet-1586	13	21	(	(	PUNCT
admet-1586	13	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-1586	13	23	)	)	PUNCT
admet-1586	13	24	.	.	PUNCT
admet-1586	14	1	keywords	keyword	NOUN
admet-1586	14	2	amorphous	amorphous	ADJ
admet-1586	14	3	;	;	PUNCT
admet-1586	14	4	microflux	microflux	PROPN
admet-1586	14	5	™	™	NOUN
admet-1586	14	6	;	;	PUNCT
admet-1586	14	7	physical	physical	ADJ
admet-1586	14	8	stability	stability	NOUN
admet-1586	14	9	;	;	PUNCT
admet-1586	14	10	raman	raman	NOUN
admet-1586	14	11	mapping	mapping	NOUN
admet-1586	14	12	;	;	PUNCT
admet-1586	14	13	x	x	X
admet-1586	14	14	-	-	NOUN
admet-1586	14	15	ray	ray	NOUN
admet-1586	14	16	powder	powder	NOUN
admet-1586	14	17	diffraction	diffraction	NOUN
admet-1586	14	18	;	;	PUNCT
admet-1586	14	19	extrusion	extrusion	NOUN
admet-1586	14	20	introduction	introduction	NOUN
admet-1586	14	21	oral	oral	ADJ
admet-1586	14	22	administration	administration	NOUN
admet-1586	14	23	is	be	AUX
admet-1586	14	24	an	an	DET
admet-1586	14	25	important	important	ADJ
admet-1586	14	26	advantage	advantage	NOUN
admet-1586	14	27	for	for	ADP
admet-1586	14	28	small	small	ADJ
admet-1586	14	29	molecular	molecular	ADJ
admet-1586	14	30	medicine	medicine	NOUN
admet-1586	14	31	because	because	SCONJ
admet-1586	14	32	medium	medium	ADJ
admet-1586	14	33	and	and	CCONJ
admet-1586	14	34	large	large	ADJ
admet-1586	14	35	molecules	molecule	NOUN
admet-1586	14	36	show	show	VERB
admet-1586	14	37	lower	low	ADJ
admet-1586	14	38	intestinal	intestinal	ADJ
admet-1586	14	39	membrane	membrane	NOUN
admet-1586	14	40	permeability	permeability	NOUN
admet-1586	14	41	,	,	PUNCT
admet-1586	14	42	followed	follow	VERB
admet-1586	14	43	by	by	ADP
admet-1586	14	44	poor	poor	ADJ
admet-1586	14	45	oral	oral	ADJ
admet-1586	14	46	absorption	absorption	NOUN
admet-1586	15	1	[	[	X
admet-1586	15	2	1	1	NUM
admet-1586	15	3	-	-	SYM
admet-1586	15	4	2	2	NUM
admet-1586	15	5	]	]	PUNCT
admet-1586	15	6	.	.	PUNCT
admet-1586	16	1	however	however	ADV
admet-1586	16	2	,	,	PUNCT
admet-1586	16	3	the	the	DET
admet-1586	16	4	number	number	NOUN
admet-1586	16	5	of	of	ADP
admet-1586	16	6	poorly	poorly	ADV
admet-1586	16	7	water	water	NOUN
admet-1586	16	8	-	-	PUNCT
admet-1586	16	9	soluble	soluble	ADJ
admet-1586	16	10	compounds	compound	NOUN
admet-1586	16	11	has	have	AUX
admet-1586	16	12	increased	increase	VERB
admet-1586	16	13	and	and	CCONJ
admet-1586	16	14	become	become	VERB
admet-1586	16	15	a	a	DET
admet-1586	16	16	key	key	ADJ
admet-1586	16	17	issue	issue	NOUN
admet-1586	16	18	for	for	ADP
admet-1586	16	19	drug	drug	NOUN
admet-1586	16	20	discovery	discovery	NOUN
admet-1586	16	21	.	.	PUNCT
admet-1586	17	1	the	the	DET
admet-1586	17	2	development	development	NOUN
admet-1586	17	3	of	of	ADP
admet-1586	17	4	small	small	ADJ
admet-1586	17	5	molecules	molecule	NOUN
admet-1586	17	6	due	due	ADP
admet-1586	17	7	to	to	ADP
admet-1586	17	8	a	a	DET
admet-1586	17	9	decrease	decrease	NOUN
admet-1586	17	10	in	in	ADP
admet-1586	17	11	aqueous	aqueous	ADJ
admet-1586	17	12	medium	medium	NOUN
admet-1586	17	13	solubility	solubility	NOUN
admet-1586	17	14	could	could	AUX
admet-1586	17	15	result	result	VERB
admet-1586	17	16	in	in	ADP
admet-1586	17	17	reduced	reduced	ADJ
admet-1586	17	18	absorption	absorption	NOUN
admet-1586	17	19	per	per	ADP
admet-1586	17	20	the	the	DET
admet-1586	17	21	oral	oral	ADJ
admet-1586	17	22	route	route	NOUN
admet-1586	17	23	[	[	X
admet-1586	17	24	3	3	NUM
admet-1586	17	25	-	-	SYM
admet-1586	17	26	4	4	NUM
admet-1586	17	27	]	]	PUNCT
admet-1586	17	28	.	.	PUNCT
admet-1586	18	1	solubility	solubility	NOUN
admet-1586	18	2	issues	issue	NOUN
admet-1586	18	3	have	have	AUX
admet-1586	18	4	been	be	AUX
admet-1586	18	5	reported	report	VERB
admet-1586	18	6	in	in	ADP
admet-1586	18	7	approximately	approximately	ADV
admet-1586	18	8	75	75	NUM
admet-1586	18	9	%	%	NOUN
admet-1586	18	10	of	of	ADP
admet-1586	18	11	new	new	ADJ
admet-1586	18	12	drug	drug	NOUN
admet-1586	18	13	candidates	candidate	NOUN
admet-1586	18	14	.	.	PUNCT
admet-1586	19	1	therefore	therefore	ADV
admet-1586	19	2	,	,	PUNCT
admet-1586	19	3	physicochemical	physicochemical	ADJ
admet-1586	19	4	and	and	CCONJ
admet-1586	19	5	pharmaceutical	pharmaceutical	NOUN
admet-1586	19	6	studies	study	NOUN
admet-1586	19	7	to	to	PART
admet-1586	19	8	improve	improve	VERB
admet-1586	19	9	solubility	solubility	NOUN
admet-1586	19	10	are	be	AUX
admet-1586	19	11	required	require	VERB
admet-1586	19	12	[	[	PUNCT
admet-1586	19	13	3	3	NUM
admet-1586	19	14	]	]	PUNCT
admet-1586	19	15	.	.	PUNCT
admet-1586	20	1	conversion	conversion	NOUN
admet-1586	20	2	of	of	ADP
admet-1586	20	3	the	the	DET
admet-1586	20	4	drug	drug	NOUN
admet-1586	20	5	form	form	NOUN
admet-1586	20	6	to	to	PART
admet-1586	20	7	salt	salt	VERB
admet-1586	20	8	and	and	CCONJ
admet-1586	20	9	cocrystal	cocrystal	ADJ
admet-1586	20	10	and	and	CCONJ
admet-1586	20	11	a	a	DET
admet-1586	20	12	reduction	reduction	NOUN
admet-1586	20	13	of	of	ADP
admet-1586	20	14	the	the	DET
admet-1586	20	15	particle	particle	NOUN
admet-1586	20	16	size	size	NOUN
admet-1586	20	17	between	between	ADP
admet-1586	20	18	the	the	DET
admet-1586	20	19	micrometer	micrometer	NOUN
admet-1586	20	20	to	to	ADP
admet-1586	20	21	nanometer	nanometer	NOUN
admet-1586	20	22	range	range	NOUN
admet-1586	20	23	are	be	AUX
admet-1586	20	24	commonly	commonly	ADV
admet-1586	20	25	attempted	attempt	VERB
admet-1586	20	26	to	to	PART
admet-1586	20	27	modify	modify	VERB
admet-1586	20	28	the	the	DET
admet-1586	20	29	physicochemical	physicochemical	ADJ
admet-1586	20	30	properties	property	NOUN
admet-1586	20	31	of	of	ADP
admet-1586	20	32	compounds	compound	NOUN
admet-1586	20	33	[	[	X
admet-1586	20	34	4	4	NUM
admet-1586	20	35	]	]	PUNCT
admet-1586	20	36	.	.	PUNCT
admet-1586	21	1	modification	modification	NOUN
admet-1586	21	2	of	of	ADP
admet-1586	21	3	drug	drug	NOUN
admet-1586	21	4	properties	property	NOUN
admet-1586	21	5	,	,	PUNCT
admet-1586	21	6	and	and	CCONJ
admet-1586	21	7	combination	combination	NOUN
admet-1586	21	8	with	with	ADP
admet-1586	21	9	co	co	NOUN
admet-1586	21	10	-	-	ADJ
admet-1586	21	11	solvent	solvent	ADJ
admet-1586	21	12	,	,	PUNCT
admet-1586	21	13	surfactant	surfactant	NOUN
admet-1586	21	14	,	,	PUNCT
admet-1586	21	15	ph	ph	NOUN
admet-1586	21	16	-	-	NOUN
admet-1586	21	17	modifier	modifier	NOUN
admet-1586	21	18	,	,	PUNCT
admet-1586	21	19	and	and	CCONJ
admet-1586	21	20	cyclodextrin	cyclodextrin	NOUN
admet-1586	21	21	,	,	PUNCT
admet-1586	21	22	have	have	AUX
admet-1586	21	23	been	be	AUX
admet-1586	21	24	considered	consider	VERB
admet-1586	21	25	as	as	ADP
admet-1586	21	26	potential	potential	ADJ
admet-1586	21	27	methods	method	NOUN
admet-1586	21	28	[	[	X
admet-1586	21	29	4	4	NUM
admet-1586	21	30	]	]	PUNCT
admet-1586	21	31	.	.	PUNCT
admet-1586	22	1	in	in	ADP
admet-1586	22	2	addition	addition	NOUN
admet-1586	22	3	,	,	PUNCT
admet-1586	22	4	amorphization	amorphization	NOUN
admet-1586	22	5	with	with	ADP
admet-1586	22	6	the	the	DET
admet-1586	22	7	disruption	disruption	NOUN
admet-1586	22	8	of	of	ADP
admet-1586	22	9	the	the	DET
admet-1586	22	10	crystal	crystal	PROPN
admet-1586	22	11	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	PROPN
admet-1586	22	12	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	PROPN
admet-1586	22	13	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-1586	22	14	mailto:hiroshi.ueda@shionogi.co.jp	mailto:hiroshi.ueda@shionogi.co.jp	PROPN
admet-1586	22	15	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-1586	22	16	h.	h.	PROPN
admet-1586	22	17	tanaka	tanaka	PROPN
admet-1586	22	18	et	et	PROPN
admet-1586	22	19	al	al	PROPN
admet-1586	22	20	.	.	PROPN
admet-1586	22	21	admet	admet	PROPN
admet-1586	22	22	&	&	CCONJ
admet-1586	22	23	dmpk	dmpk	PROPN
admet-1586	22	24	11(3	11(3	NUM
admet-1586	22	25	)	)	PUNCT
admet-1586	22	26	(	(	PUNCT
admet-1586	22	27	2023	2023	NUM
admet-1586	22	28	)	)	PUNCT
admet-1586	22	29	373	373	NUM
admet-1586	22	30	-	-	SYM
admet-1586	22	31	385	385	NUM
admet-1586	22	32	374	374	NUM
admet-1586	22	33	lattice	lattice	NOUN
admet-1586	22	34	of	of	ADP
admet-1586	22	35	the	the	DET
admet-1586	22	36	compound	compound	NOUN
admet-1586	22	37	has	have	AUX
admet-1586	22	38	been	be	AUX
admet-1586	22	39	reported	report	VERB
admet-1586	22	40	to	to	PART
admet-1586	22	41	enhance	enhance	VERB
admet-1586	22	42	solubility	solubility	NOUN
admet-1586	22	43	[	[	X
admet-1586	22	44	4	4	NUM
admet-1586	22	45	-	-	SYM
admet-1586	22	46	6	6	NUM
admet-1586	22	47	]	]	PUNCT
admet-1586	22	48	.	.	PUNCT
admet-1586	23	1	since	since	SCONJ
admet-1586	23	2	the	the	DET
admet-1586	23	3	amorphous	amorphous	ADJ
admet-1586	23	4	form	form	NOUN
admet-1586	23	5	is	be	AUX
admet-1586	23	6	thermodynamically	thermodynamically	ADV
admet-1586	23	7	unstable	unstable	ADJ
admet-1586	23	8	and	and	CCONJ
admet-1586	23	9	might	might	AUX
admet-1586	23	10	cause	cause	VERB
admet-1586	23	11	crystallization	crystallization	NOUN
admet-1586	23	12	during	during	ADP
admet-1586	23	13	the	the	DET
admet-1586	23	14	formulation	formulation	NOUN
admet-1586	23	15	process	process	NOUN
admet-1586	23	16	and/or	and/or	CCONJ
admet-1586	23	17	storage	storage	NOUN
admet-1586	23	18	,	,	PUNCT
admet-1586	23	19	stabilization	stabilization	NOUN
admet-1586	23	20	of	of	ADP
admet-1586	23	21	amorphous	amorphous	ADJ
admet-1586	23	22	drugs	drug	NOUN
admet-1586	23	23	by	by	ADP
admet-1586	23	24	combination	combination	NOUN
admet-1586	23	25	with	with	ADP
admet-1586	23	26	a	a	DET
admet-1586	23	27	hydrophilic	hydrophilic	ADJ
admet-1586	23	28	polymer	polymer	NOUN
admet-1586	23	29	as	as	SCONJ
admet-1586	23	30	a	a	DET
admet-1586	23	31	carrier	carrier	NOUN
admet-1586	23	32	was	be	AUX
admet-1586	23	33	designed	design	VERB
admet-1586	23	34	as	as	ADP
admet-1586	23	35	polymeric	polymeric	ADJ
admet-1586	23	36	solid	solid	ADJ
admet-1586	23	37	dispersion	dispersion	NOUN
admet-1586	23	38	[	[	X
admet-1586	23	39	5,6	5,6	NUM
admet-1586	23	40	]	]	X
admet-1586	23	41	.	.	PUNCT
admet-1586	24	1	miscible	miscible	ADJ
admet-1586	24	2	dispersion	dispersion	NOUN
admet-1586	24	3	of	of	ADP
admet-1586	24	4	amorphous	amorphous	ADJ
admet-1586	24	5	drugs	drug	NOUN
admet-1586	24	6	into	into	ADP
admet-1586	24	7	a	a	DET
admet-1586	24	8	polymeric	polymeric	ADJ
admet-1586	24	9	carrier	carrier	NOUN
admet-1586	24	10	with	with	ADP
admet-1586	24	11	the	the	DET
admet-1586	24	12	formation	formation	NOUN
admet-1586	24	13	of	of	ADP
admet-1586	24	14	intermolecular	intermolecular	ADJ
admet-1586	24	15	interaction	interaction	NOUN
admet-1586	24	16	could	could	AUX
admet-1586	24	17	decrease	decrease	VERB
admet-1586	24	18	the	the	DET
admet-1586	24	19	molecular	molecular	ADJ
admet-1586	24	20	mobility	mobility	NOUN
admet-1586	24	21	,	,	PUNCT
admet-1586	24	22	which	which	PRON
admet-1586	24	23	inhibits	inhibit	VERB
admet-1586	24	24	crystallization	crystallization	NOUN
admet-1586	24	25	of	of	ADP
admet-1586	24	26	the	the	DET
admet-1586	24	27	amorphous	amorphous	ADJ
admet-1586	24	28	drug	drug	NOUN
admet-1586	24	29	[	[	X
admet-1586	24	30	7,8	7,8	NUM
admet-1586	24	31	]	]	PUNCT
admet-1586	24	32	.	.	PUNCT
admet-1586	25	1	however	however	ADV
admet-1586	25	2	,	,	PUNCT
admet-1586	25	3	the	the	DET
admet-1586	25	4	formulation	formulation	NOUN
admet-1586	25	5	process	process	NOUN
admet-1586	25	6	is	be	AUX
admet-1586	25	7	a	a	DET
admet-1586	25	8	major	major	ADJ
admet-1586	25	9	concern	concern	NOUN
admet-1586	25	10	for	for	ADP
admet-1586	25	11	the	the	DET
admet-1586	25	12	manufacturing	manufacturing	NOUN
admet-1586	25	13	of	of	ADP
admet-1586	25	14	solid	solid	ADJ
admet-1586	25	15	dispersion	dispersion	NOUN
admet-1586	25	16	,	,	PUNCT
admet-1586	25	17	where	where	SCONJ
admet-1586	25	18	solvent	solvent	NOUN
admet-1586	25	19	-	-	PUNCT
admet-1586	25	20	mediated	mediate	VERB
admet-1586	25	21	and	and	CCONJ
admet-1586	25	22	fusion	fusion	NOUN
admet-1586	25	23	methods	method	NOUN
admet-1586	25	24	have	have	AUX
admet-1586	25	25	been	be	AUX
admet-1586	25	26	utilized	utilize	VERB
admet-1586	25	27	[	[	PUNCT
admet-1586	25	28	9	9	NUM
admet-1586	25	29	]	]	PUNCT
admet-1586	25	30	.	.	PUNCT
admet-1586	26	1	the	the	DET
admet-1586	26	2	solvent	solvent	NOUN
admet-1586	26	3	-	-	PUNCT
admet-1586	26	4	mediated	mediate	VERB
admet-1586	26	5	technique	technique	NOUN
admet-1586	26	6	involves	involve	VERB
admet-1586	26	7	spraydrying	spraydrying	NOUN
admet-1586	26	8	drugs	drug	NOUN
admet-1586	26	9	and	and	CCONJ
admet-1586	26	10	dissolving	dissolve	VERB
admet-1586	26	11	polymeric	polymeric	ADJ
admet-1586	26	12	carriers	carrier	NOUN
admet-1586	26	13	in	in	ADP
admet-1586	26	14	organic	organic	ADJ
admet-1586	26	15	and/or	and/or	CCONJ
admet-1586	26	16	aqueous	aqueous	ADJ
admet-1586	26	17	solvents	solvent	NOUN
admet-1586	26	18	.	.	PUNCT
admet-1586	27	1	rapid	rapid	ADJ
admet-1586	27	2	evaporation	evaporation	NOUN
admet-1586	27	3	of	of	ADP
admet-1586	27	4	solvent	solvent	ADJ
admet-1586	27	5	results	result	NOUN
admet-1586	27	6	in	in	ADP
admet-1586	27	7	drug	drug	NOUN
admet-1586	27	8	amorphization	amorphization	NOUN
admet-1586	27	9	with	with	ADP
admet-1586	27	10	miscible	miscible	ADJ
admet-1586	27	11	dispersion	dispersion	NOUN
admet-1586	27	12	into	into	ADP
admet-1586	27	13	the	the	DET
admet-1586	27	14	polymeric	polymeric	ADJ
admet-1586	27	15	carrier	carrier	NOUN
admet-1586	27	16	at	at	ADP
admet-1586	27	17	the	the	DET
admet-1586	27	18	molecular	molecular	ADJ
admet-1586	27	19	level	level	NOUN
admet-1586	27	20	.	.	PUNCT
admet-1586	28	1	in	in	ADP
admet-1586	28	2	contrast	contrast	NOUN
admet-1586	28	3	,	,	PUNCT
admet-1586	28	4	hot	hot	ADJ
admet-1586	28	5	-	-	PUNCT
admet-1586	28	6	melt	melt	NOUN
admet-1586	28	7	extrusion	extrusion	NOUN
admet-1586	28	8	is	be	AUX
admet-1586	28	9	a	a	DET
admet-1586	28	10	process	process	NOUN
admet-1586	28	11	that	that	PRON
admet-1586	28	12	does	do	AUX
admet-1586	28	13	not	not	PART
admet-1586	28	14	use	use	VERB
admet-1586	28	15	solvent	solvent	NOUN
admet-1586	28	16	as	as	ADP
admet-1586	28	17	a	a	DET
admet-1586	28	18	representative	representative	ADJ
admet-1586	28	19	fusion	fusion	NOUN
admet-1586	28	20	technique	technique	NOUN
admet-1586	28	21	.	.	PUNCT
admet-1586	29	1	high	high	ADJ
admet-1586	29	2	-	-	PUNCT
admet-1586	29	3	shared	share	VERB
admet-1586	29	4	mixing	mixing	NOUN
admet-1586	29	5	of	of	ADP
admet-1586	29	6	drug	drug	NOUN
admet-1586	29	7	and	and	CCONJ
admet-1586	29	8	polymeric	polymeric	ADJ
admet-1586	29	9	carrier	carrier	NOUN
admet-1586	29	10	using	use	VERB
admet-1586	29	11	a	a	DET
admet-1586	29	12	twin	twin	ADJ
admet-1586	29	13	rotating	rotating	NOUN
admet-1586	29	14	screw	screw	NOUN
admet-1586	29	15	over	over	ADP
admet-1586	29	16	the	the	DET
admet-1586	29	17	glass	glass	NOUN
admet-1586	29	18	transition	transition	NOUN
admet-1586	29	19	temperature	temperature	NOUN
admet-1586	29	20	(	(	PUNCT
admet-1586	29	21	tg	tg	PROPN
admet-1586	29	22	)	)	PUNCT
admet-1586	29	23	of	of	ADP
admet-1586	29	24	a	a	DET
admet-1586	29	25	polymeric	polymeric	ADJ
admet-1586	29	26	carrier	carrier	NOUN
admet-1586	29	27	can	can	AUX
admet-1586	29	28	transform	transform	VERB
admet-1586	29	29	the	the	DET
admet-1586	29	30	polymeric	polymeric	ADJ
admet-1586	29	31	carrier	carrier	NOUN
admet-1586	29	32	to	to	ADP
admet-1586	29	33	a	a	DET
admet-1586	29	34	rubber	rubber	NOUN
admet-1586	29	35	state	state	NOUN
admet-1586	29	36	.	.	PUNCT
admet-1586	30	1	subsequently	subsequently	ADV
admet-1586	30	2	,	,	PUNCT
admet-1586	30	3	crystalline	crystalline	PROPN
admet-1586	30	4	drug	drug	NOUN
admet-1586	30	5	co	co	NOUN
admet-1586	30	6	-	-	VERB
admet-1586	30	7	melted	melt	VERB
admet-1586	30	8	with	with	ADP
admet-1586	30	9	rubbery	rubbery	ADJ
admet-1586	30	10	polymeric	polymeric	ADJ
admet-1586	30	11	carrier	carrier	NOUN
admet-1586	30	12	under	under	ADP
admet-1586	30	13	high	high	ADV
admet-1586	30	14	-	-	PUNCT
admet-1586	30	15	shared	share	VERB
admet-1586	30	16	mixing	mixing	NOUN
admet-1586	30	17	results	result	NOUN
admet-1586	30	18	in	in	ADP
admet-1586	30	19	a	a	DET
admet-1586	30	20	miscible	miscible	ADJ
admet-1586	30	21	amorphous	amorphous	ADJ
admet-1586	30	22	blend	blend	NOUN
admet-1586	30	23	as	as	ADP
admet-1586	30	24	a	a	DET
admet-1586	30	25	solid	solid	ADJ
admet-1586	30	26	dispersion	dispersion	NOUN
admet-1586	30	27	.	.	PUNCT
admet-1586	31	1	although	although	SCONJ
admet-1586	31	2	both	both	DET
admet-1586	31	3	processes	process	NOUN
admet-1586	31	4	are	be	AUX
admet-1586	31	5	effective	effective	ADJ
admet-1586	31	6	,	,	PUNCT
admet-1586	31	7	recent	recent	ADJ
admet-1586	31	8	environmental	environmental	ADJ
admet-1586	31	9	concerns	concern	NOUN
admet-1586	31	10	have	have	AUX
admet-1586	31	11	led	lead	VERB
admet-1586	31	12	to	to	ADP
admet-1586	31	13	hot	hot	ADJ
admet-1586	31	14	-	-	PUNCT
admet-1586	31	15	melt	melt	NOUN
admet-1586	31	16	extrusion	extrusion	NOUN
admet-1586	31	17	being	be	AUX
admet-1586	31	18	considered	consider	VERB
admet-1586	31	19	more	more	ADV
admet-1586	31	20	attractive	attractive	ADJ
admet-1586	31	21	as	as	SCONJ
admet-1586	31	22	it	it	PRON
admet-1586	31	23	is	be	AUX
admet-1586	31	24	a	a	DET
admet-1586	31	25	solventfree	solventfree	ADJ
admet-1586	31	26	process	process	NOUN
admet-1586	31	27	[	[	X
admet-1586	31	28	8	8	NUM
admet-1586	31	29	]	]	PUNCT
admet-1586	31	30	.	.	PUNCT
admet-1586	32	1	commercial	commercial	ADJ
admet-1586	32	2	products	product	NOUN
admet-1586	32	3	of	of	ADP
admet-1586	32	4	solid	solid	ADJ
admet-1586	32	5	dispersion	dispersion	NOUN
admet-1586	32	6	prepared	prepare	VERB
admet-1586	32	7	by	by	ADP
admet-1586	32	8	hot	hot	ADJ
admet-1586	32	9	-	-	PUNCT
admet-1586	32	10	melt	melt	NOUN
admet-1586	32	11	extrusion	extrusion	NOUN
admet-1586	32	12	can	can	AUX
admet-1586	32	13	comprise	comprise	VERB
admet-1586	32	14	various	various	ADJ
admet-1586	32	15	polymeric	polymeric	ADJ
admet-1586	32	16	carriers	carrier	NOUN
admet-1586	32	17	[	[	X
admet-1586	32	18	8	8	NUM
admet-1586	32	19	]	]	PUNCT
admet-1586	32	20	.	.	PUNCT
admet-1586	33	1	polyvinylpyrrolidone	polyvinylpyrrolidone	NOUN
admet-1586	33	2	,	,	PUNCT
admet-1586	33	3	copovidone	copovidone	NOUN
admet-1586	33	4	,	,	PUNCT
admet-1586	33	5	and	and	CCONJ
admet-1586	33	6	cellulosic	cellulosic	NOUN
admet-1586	33	7	polymers	polymer	NOUN
admet-1586	33	8	are	be	AUX
admet-1586	33	9	widely	widely	ADV
admet-1586	33	10	used	use	VERB
admet-1586	33	11	in	in	ADP
admet-1586	33	12	commercially	commercially	ADV
admet-1586	33	13	and	and	CCONJ
admet-1586	33	14	in	in	ADP
admet-1586	33	15	research	research	NOUN
admet-1586	33	16	[	[	X
admet-1586	33	17	8	8	NUM
admet-1586	33	18	-	-	SYM
admet-1586	33	19	12	12	NUM
admet-1586	33	20	]	]	PUNCT
admet-1586	33	21	.	.	PUNCT
admet-1586	34	1	studies	study	NOUN
admet-1586	34	2	on	on	ADP
admet-1586	34	3	polymeric	polymeric	ADJ
admet-1586	34	4	carriers	carrier	NOUN
admet-1586	34	5	revealed	reveal	VERB
admet-1586	34	6	that	that	SCONJ
admet-1586	34	7	hydroxypropyl	hydroxypropyl	VERB
admet-1586	34	8	methylcellulose	methylcellulose	NOUN
admet-1586	34	9	acetate	acetate	NOUN
admet-1586	34	10	succinate	succinate	NOUN
admet-1586	34	11	(	(	PUNCT
admet-1586	34	12	hpmcas	hpmcas	PROPN
admet-1586	34	13	)	)	PUNCT
admet-1586	34	14	has	have	VERB
admet-1586	34	15	better	well	ADJ
admet-1586	34	16	physical	physical	ADJ
admet-1586	34	17	stability	stability	NOUN
admet-1586	34	18	and	and	CCONJ
admet-1586	34	19	oral	oral	ADJ
admet-1586	34	20	absorption	absorption	NOUN
admet-1586	34	21	than	than	ADP
admet-1586	34	22	other	other	ADJ
admet-1586	34	23	carriers	carrier	NOUN
admet-1586	34	24	[	[	PUNCT
admet-1586	34	25	13	13	NUM
admet-1586	34	26	-	-	SYM
admet-1586	34	27	15	15	NUM
admet-1586	34	28	]	]	PUNCT
admet-1586	34	29	and	and	CCONJ
admet-1586	34	30	is	be	AUX
admet-1586	34	31	used	use	VERB
admet-1586	34	32	in	in	ADP
admet-1586	34	33	a	a	DET
admet-1586	34	34	commercial	commercial	ADJ
admet-1586	34	35	product	product	NOUN
admet-1586	34	36	,	,	PUNCT
admet-1586	34	37	“	"	PUNCT
admet-1586	34	38	noxafil	noxafil	VERB
admet-1586	34	39	“	"	PUNCT
admet-1586	34	40	.	.	PUNCT
admet-1586	35	1	although	although	SCONJ
admet-1586	35	2	an	an	DET
admet-1586	35	3	advantage	advantage	NOUN
admet-1586	35	4	for	for	ADP
admet-1586	35	5	solvent	solvent	NOUN
admet-1586	35	6	-	-	PUNCT
admet-1586	35	7	free	free	ADJ
admet-1586	35	8	processes	process	NOUN
admet-1586	35	9	,	,	PUNCT
admet-1586	35	10	elevation	elevation	NOUN
admet-1586	35	11	of	of	ADP
admet-1586	35	12	the	the	DET
admet-1586	35	13	hot	hot	ADJ
admet-1586	35	14	-	-	PUNCT
admet-1586	35	15	melt	melt	NOUN
admet-1586	35	16	extrusion	extrusion	NOUN
admet-1586	35	17	temperature	temperature	NOUN
admet-1586	35	18	is	be	AUX
admet-1586	35	19	limited	limit	VERB
admet-1586	35	20	because	because	SCONJ
admet-1586	35	21	thermal	thermal	ADJ
admet-1586	35	22	degradation	degradation	NOUN
admet-1586	35	23	of	of	ADP
admet-1586	35	24	the	the	DET
admet-1586	35	25	drug	drug	NOUN
admet-1586	35	26	and/or	and/or	CCONJ
admet-1586	35	27	polymeric	polymeric	ADJ
admet-1586	35	28	carrier	carrier	NOUN
admet-1586	35	29	may	may	AUX
admet-1586	35	30	occur	occur	VERB
admet-1586	35	31	[	[	X
admet-1586	35	32	16	16	NUM
admet-1586	35	33	]	]	PUNCT
admet-1586	35	34	.	.	PUNCT
admet-1586	36	1	to	to	PART
admet-1586	36	2	overcome	overcome	VERB
admet-1586	36	3	this	this	DET
admet-1586	36	4	problem	problem	NOUN
admet-1586	36	5	,	,	PUNCT
admet-1586	36	6	a	a	DET
admet-1586	36	7	study	study	NOUN
admet-1586	36	8	on	on	ADP
admet-1586	36	9	tadalafil	tadalafil	PROPN
admet-1586	36	10	,	,	PUNCT
admet-1586	36	11	a	a	DET
admet-1586	36	12	known	know	VERB
admet-1586	36	13	heat	heat	NOUN
admet-1586	36	14	-	-	PUNCT
admet-1586	36	15	sensitive	sensitive	ADJ
admet-1586	36	16	drug	drug	NOUN
admet-1586	36	17	with	with	ADP
admet-1586	36	18	a	a	DET
admet-1586	36	19	high	high	ADJ
admet-1586	36	20	melting	melting	NOUN
admet-1586	36	21	temperature	temperature	NOUN
admet-1586	36	22	(	(	PUNCT
admet-1586	36	23	tm	tm	NOUN
admet-1586	36	24	)	)	PUNCT
admet-1586	36	25	,	,	PUNCT
admet-1586	36	26	was	be	AUX
admet-1586	36	27	performed	perform	VERB
admet-1586	36	28	[	[	PUNCT
admet-1586	36	29	16	16	NUM
admet-1586	36	30	]	]	PUNCT
admet-1586	36	31	.	.	PUNCT
admet-1586	37	1	the	the	DET
admet-1586	37	2	addition	addition	NOUN
admet-1586	37	3	of	of	ADP
admet-1586	37	4	surfactant	surfactant	NOUN
admet-1586	37	5	as	as	ADP
admet-1586	37	6	a	a	DET
admet-1586	37	7	plasticizer	plasticizer	NOUN
admet-1586	37	8	to	to	ADP
admet-1586	37	9	a	a	DET
admet-1586	37	10	polymeric	polymeric	ADJ
admet-1586	37	11	carrier	carrier	NOUN
admet-1586	37	12	could	could	AUX
admet-1586	37	13	cause	cause	VERB
admet-1586	37	14	a	a	DET
admet-1586	37	15	reduction	reduction	NOUN
admet-1586	37	16	in	in	ADP
admet-1586	37	17	tg	tg	PROPN
admet-1586	37	18	,	,	PUNCT
admet-1586	37	19	enabling	enable	VERB
admet-1586	37	20	the	the	DET
admet-1586	37	21	hot	hot	ADJ
admet-1586	37	22	-	-	PUNCT
admet-1586	37	23	melt	melt	NOUN
admet-1586	37	24	extrusion	extrusion	NOUN
admet-1586	37	25	process	process	NOUN
admet-1586	37	26	to	to	PART
admet-1586	37	27	be	be	AUX
admet-1586	37	28	performed	perform	VERB
admet-1586	37	29	at	at	ADP
admet-1586	37	30	a	a	DET
admet-1586	37	31	lower	low	ADJ
admet-1586	37	32	temperature	temperature	NOUN
admet-1586	37	33	[	[	X
admet-1586	37	34	17,18	17,18	NUM
admet-1586	37	35	]	]	PUNCT
admet-1586	37	36	.	.	PUNCT
admet-1586	38	1	hence	hence	ADV
admet-1586	38	2	,	,	PUNCT
admet-1586	38	3	designing	design	VERB
admet-1586	38	4	and	and	CCONJ
admet-1586	38	5	developing	develop	VERB
admet-1586	38	6	a	a	DET
admet-1586	38	7	novel	novel	ADJ
admet-1586	38	8	solid	solid	ADJ
admet-1586	38	9	dispersion	dispersion	NOUN
admet-1586	38	10	carrier	carrier	NOUN
admet-1586	38	11	with	with	ADP
admet-1586	38	12	lower	low	ADJ
admet-1586	38	13	tg	tg	PROPN
admet-1586	38	14	is	be	AUX
admet-1586	38	15	desirable	desirable	ADJ
admet-1586	38	16	.	.	PUNCT
admet-1586	39	1	in	in	ADP
admet-1586	39	2	a	a	DET
admet-1586	39	3	previous	previous	ADJ
admet-1586	39	4	study	study	NOUN
admet-1586	39	5	,	,	PUNCT
admet-1586	39	6	we	we	PRON
admet-1586	39	7	focused	focus	VERB
admet-1586	39	8	on	on	ADP
admet-1586	39	9	an	an	DET
admet-1586	39	10	experimental	experimental	ADJ
admet-1586	39	11	grade	grade	NOUN
admet-1586	39	12	of	of	ADP
admet-1586	39	13	hpmcas	hpmca	NOUN
admet-1586	39	14	originally	originally	ADV
admet-1586	39	15	designed	design	VERB
admet-1586	39	16	with	with	ADP
admet-1586	39	17	lower	low	ADJ
admet-1586	39	18	tg	tg	NOUN
admet-1586	39	19	than	than	ADP
admet-1586	39	20	commercial	commercial	ADJ
admet-1586	39	21	grade	grade	NOUN
admet-1586	39	22	[	[	X
admet-1586	39	23	19	19	NUM
admet-1586	39	24	]	]	PUNCT
admet-1586	39	25	.	.	PUNCT
admet-1586	40	1	physicochemical	physicochemical	ADJ
admet-1586	40	2	investigation	investigation	NOUN
admet-1586	40	3	of	of	ADP
admet-1586	40	4	its	its	PRON
admet-1586	40	5	solid	solid	ADJ
admet-1586	40	6	dispersion	dispersion	NOUN
admet-1586	40	7	revealed	reveal	VERB
admet-1586	40	8	the	the	DET
admet-1586	40	9	formation	formation	NOUN
admet-1586	40	10	of	of	ADP
admet-1586	40	11	intermolecular	intermolecular	ADJ
admet-1586	40	12	interaction	interaction	NOUN
admet-1586	40	13	with	with	ADP
admet-1586	40	14	indomethacin	indomethacin	PROPN
admet-1586	40	15	(	(	PUNCT
admet-1586	40	16	imc	imc	PROPN
admet-1586	40	17	)	)	PUNCT
admet-1586	40	18	inhibited	inhibited	ADJ
admet-1586	40	19	crystallization	crystallization	NOUN
admet-1586	40	20	.	.	PUNCT
admet-1586	41	1	even	even	ADV
admet-1586	41	2	though	though	SCONJ
admet-1586	41	3	the	the	DET
admet-1586	41	4	tg	tg	PROPN
admet-1586	41	5	of	of	ADP
admet-1586	41	6	an	an	DET
admet-1586	41	7	experimental	experimental	ADJ
admet-1586	41	8	grade	grade	NOUN
admet-1586	41	9	hpmcas	hpmca	NOUN
admet-1586	41	10	was	be	AUX
admet-1586	41	11	lower	low	ADJ
admet-1586	41	12	than	than	ADP
admet-1586	41	13	that	that	PRON
admet-1586	41	14	of	of	ADP
admet-1586	41	15	commercial	commercial	ADJ
admet-1586	41	16	grade	grade	NOUN
admet-1586	41	17	,	,	PUNCT
admet-1586	41	18	their	their	PRON
admet-1586	41	19	performances	performance	NOUN
admet-1586	41	20	were	be	AUX
admet-1586	41	21	comparable	comparable	ADJ
admet-1586	41	22	.	.	PUNCT
admet-1586	42	1	this	this	DET
admet-1586	42	2	study	study	NOUN
admet-1586	42	3	aimed	aim	VERB
admet-1586	42	4	to	to	PART
admet-1586	42	5	investigate	investigate	VERB
admet-1586	42	6	the	the	DET
admet-1586	42	7	applicability	applicability	NOUN
admet-1586	42	8	of	of	ADP
admet-1586	42	9	an	an	DET
admet-1586	42	10	experimental	experimental	ADJ
admet-1586	42	11	grade	grade	NOUN
admet-1586	42	12	hpmcas	hpmca	NOUN
admet-1586	42	13	to	to	ADP
admet-1586	42	14	the	the	DET
admet-1586	42	15	hot	hot	ADJ
admet-1586	42	16	-	-	PUNCT
admet-1586	42	17	melt	melt	NOUN
admet-1586	42	18	extrusion	extrusion	NOUN
admet-1586	42	19	process	process	NOUN
admet-1586	42	20	and	and	CCONJ
admet-1586	42	21	the	the	DET
admet-1586	42	22	dissolutionpermeation	dissolutionpermeation	NOUN
admet-1586	42	23	performance	performance	NOUN
admet-1586	42	24	of	of	ADP
admet-1586	42	25	the	the	DET
admet-1586	42	26	extruded	extrude	VERB
admet-1586	42	27	solid	solid	ADJ
admet-1586	42	28	dispersion	dispersion	NOUN
admet-1586	42	29	.	.	PUNCT
admet-1586	43	1	indomethacin	indomethacin	PROPN
admet-1586	43	2	was	be	AUX
admet-1586	43	3	employed	employ	VERB
admet-1586	43	4	as	as	ADP
admet-1586	43	5	the	the	DET
admet-1586	43	6	model	model	NOUN
admet-1586	43	7	drug	drug	NOUN
admet-1586	43	8	,	,	PUNCT
admet-1586	43	9	and	and	CCONJ
admet-1586	43	10	a	a	DET
admet-1586	43	11	commercial	commercial	ADJ
admet-1586	43	12	grade	grade	NOUN
admet-1586	43	13	of	of	ADP
admet-1586	43	14	hpmcas	hpmca	NOUN
admet-1586	43	15	was	be	AUX
admet-1586	43	16	used	use	VERB
admet-1586	43	17	for	for	ADP
admet-1586	43	18	comparison	comparison	NOUN
admet-1586	43	19	.	.	PUNCT
admet-1586	44	1	experimental	experimental	ADJ
admet-1586	44	2	materials	material	NOUN
admet-1586	44	3	indomethacin	indomethacin	NOUN
admet-1586	44	4	was	be	AUX
admet-1586	44	5	purchased	purchase	VERB
admet-1586	44	6	from	from	ADP
admet-1586	44	7	kongo	kongo	PROPN
admet-1586	44	8	chemical	chemical	PROPN
admet-1586	44	9	co.	co.	PROPN
admet-1586	44	10	,	,	PUNCT
admet-1586	44	11	ltd	ltd	PROPN
admet-1586	44	12	.	.	PROPN
admet-1586	44	13	(	(	PUNCT
admet-1586	44	14	toyama	toyama	PROPN
admet-1586	44	15	,	,	PUNCT
admet-1586	44	16	japan	japan	PROPN
admet-1586	44	17	)	)	PUNCT
admet-1586	44	18	.	.	PUNCT
admet-1586	45	1	a	a	DET
admet-1586	45	2	commercial	commercial	ADJ
admet-1586	45	3	grade	grade	NOUN
admet-1586	45	4	of	of	ADP
admet-1586	45	5	hpmcas	hpmca	NOUN
admet-1586	45	6	“	"	PUNCT
admet-1586	45	7	shin	shin	NOUN
admet-1586	45	8	-	-	PUNCT
admet-1586	45	9	etsu	etsu	NOUN
admet-1586	45	10	aqoat	aqoat	NOUN
admet-1586	45	11	®	®	PROPN
admet-1586	45	12	type	type	NOUN
admet-1586	45	13	mg	mg	PROPN
admet-1586	45	14	”	"	PUNCT
admet-1586	45	15	and	and	CCONJ
admet-1586	45	16	an	an	DET
admet-1586	45	17	experimental	experimental	ADJ
admet-1586	45	18	grade	grade	NOUN
admet-1586	45	19	“	"	PUNCT
admet-1586	45	20	type	type	NOUN
admet-1586	45	21	mx	mx	NOUN
admet-1586	45	22	”	"	PUNCT
admet-1586	45	23	originally	originally	ADV
admet-1586	45	24	developed	develop	VERB
admet-1586	45	25	were	be	AUX
admet-1586	45	26	kindly	kindly	ADV
admet-1586	45	27	gifted	gifted	ADJ
admet-1586	45	28	by	by	ADP
admet-1586	45	29	shin	shin	NOUN
admet-1586	45	30	-	-	PUNCT
admet-1586	45	31	etsu	etsu	PROPN
admet-1586	45	32	chemical	chemical	PROPN
admet-1586	45	33	co.	co.	PROPN
admet-1586	45	34	,	,	PUNCT
admet-1586	45	35	ltd	ltd	PROPN
admet-1586	45	36	.	.	PROPN
admet-1586	46	1	(	(	PUNCT
admet-1586	46	2	tokyo	tokyo	PROPN
admet-1586	46	3	,	,	PUNCT
admet-1586	46	4	japan	japan	PROPN
admet-1586	46	5	)	)	PUNCT
admet-1586	47	1	[	[	X
admet-1586	47	2	19	19	NUM
admet-1586	47	3	]	]	PUNCT
admet-1586	47	4	.	.	PUNCT
admet-1586	48	1	git-0	git-0	NOUN
admet-1586	48	2	lipid	lipid	NOUN
admet-1586	48	3	(	(	PUNCT
admet-1586	48	4	20	20	NUM
admet-1586	48	5	wt.%	wt.%	ADJ
admet-1586	48	6	phospholipid	phospholipid	NOUN
admet-1586	48	7	dissolved	dissolve	VERB
admet-1586	48	8	into	into	ADP
admet-1586	48	9	dodecane	dodecane	PROPN
admet-1586	48	10	)	)	PUNCT
admet-1586	48	11	,	,	PUNCT
admet-1586	48	12	prisma	prisma	VERB
admet-1586	48	13	ht	ht	PROPN
admet-1586	48	14	buffer	buffer	NOUN
admet-1586	48	15	(	(	PUNCT
admet-1586	48	16	ph	ph	NOUN
admet-1586	48	17	6.5	6.5	NUM
admet-1586	48	18	)	)	PUNCT
admet-1586	48	19	,	,	PUNCT
admet-1586	48	20	and	and	CCONJ
admet-1586	48	21	acceptor	acceptor	NOUN
admet-1586	48	22	sink	sink	NOUN
admet-1586	48	23	buffer	buffer	NOUN
admet-1586	48	24	(	(	PUNCT
admet-1586	48	25	asb	asb	PROPN
admet-1586	48	26	)	)	PUNCT
admet-1586	48	27	were	be	AUX
admet-1586	48	28	purchased	purchase	VERB
admet-1586	48	29	from	from	ADP
admet-1586	48	30	pion	pion	PROPN
admet-1586	48	31	inc	inc	PROPN
admet-1586	48	32	.	.	PROPN
admet-1586	48	33	(	(	PUNCT
admet-1586	48	34	ma	ma	PROPN
admet-1586	48	35	,	,	PUNCT
admet-1586	48	36	usa	usa	PROPN
admet-1586	48	37	)	)	PUNCT
admet-1586	48	38	.	.	PUNCT
admet-1586	49	1	admet	admet	PROPN
admet-1586	49	2	&	&	CCONJ
admet-1586	49	3	dmpk	dmpk	PROPN
admet-1586	49	4	11(3	11(3	NUM
admet-1586	49	5	)	)	PUNCT
admet-1586	49	6	(	(	PUNCT
admet-1586	49	7	2023	2023	NUM
admet-1586	49	8	)	)	PUNCT
admet-1586	49	9	373	373	NUM
admet-1586	49	10	-	-	SYM
admet-1586	49	11	385	385	NUM
admet-1586	49	12	dissolution	dissolution	NOUN
admet-1586	49	13	-	-	PUNCT
admet-1586	49	14	permeation	permeation	NOUN
admet-1586	49	15	of	of	ADP
admet-1586	49	16	hot	hot	ADJ
admet-1586	49	17	-	-	PUNCT
admet-1586	49	18	melt	melt	NOUN
admet-1586	49	19	extruded	extrude	VERB
admet-1586	49	20	asd	asd	NOUN
admet-1586	49	21	doi	doi	PROPN
admet-1586	49	22	:	:	PUNCT
admet-1586	49	23	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	NOUN
admet-1586	49	24	375	375	NUM
admet-1586	49	25	preparation	preparation	NOUN
admet-1586	49	26	of	of	ADP
admet-1586	49	27	solid	solid	ADJ
admet-1586	49	28	dispersion	dispersion	NOUN
admet-1586	49	29	solid	solid	ADJ
admet-1586	49	30	dispersion	dispersion	NOUN
admet-1586	49	31	formulations	formulation	NOUN
admet-1586	49	32	were	be	AUX
admet-1586	49	33	prepared	prepare	VERB
admet-1586	49	34	by	by	ADP
admet-1586	49	35	hot	hot	ADJ
admet-1586	49	36	-	-	PUNCT
admet-1586	49	37	melt	melt	NOUN
admet-1586	49	38	extrusion	extrusion	NOUN
admet-1586	49	39	(	(	PUNCT
admet-1586	49	40	hme	hme	NOUN
admet-1586	49	41	)	)	PUNCT
admet-1586	49	42	process	process	NOUN
admet-1586	49	43	using	use	VERB
admet-1586	49	44	a	a	DET
admet-1586	49	45	micro	micro	ADJ
admet-1586	49	46	-	-	ADJ
admet-1586	49	47	conical	conical	ADJ
admet-1586	49	48	twin	twin	NOUN
admet-1586	49	49	-	-	PUNCT
admet-1586	49	50	screw	screw	NOUN
admet-1586	49	51	compounder	compounder	NOUN
admet-1586	49	52	“	"	PUNCT
admet-1586	49	53	haake	haake	VERB
admet-1586	49	54	™	™	ADJ
admet-1586	49	55	mini	mini	ADJ
admet-1586	49	56	ctw	ctw	NOUN
admet-1586	49	57	”	"	PUNCT
admet-1586	49	58	(	(	PUNCT
admet-1586	49	59	thermo	thermo	NOUN
admet-1586	49	60	fisher	fisher	PROPN
admet-1586	49	61	scientific	scientific	PROPN
admet-1586	49	62	inc	inc	PROPN
admet-1586	49	63	.	.	PROPN
admet-1586	49	64	,	,	PUNCT
admet-1586	49	65	tokyo	tokyo	PROPN
admet-1586	49	66	,	,	PUNCT
admet-1586	49	67	japan	japan	PROPN
admet-1586	49	68	)	)	PUNCT
admet-1586	49	69	.	.	PUNCT
admet-1586	50	1	physical	physical	ADJ
admet-1586	50	2	mixtures	mixture	NOUN
admet-1586	50	3	comprising	comprise	VERB
admet-1586	50	4	imc	imc	PROPN
admet-1586	50	5	and	and	CCONJ
admet-1586	50	6	hpmcas	hpmca	NOUN
admet-1586	50	7	-	-	PUNCT
admet-1586	50	8	mg	mg	PROPN
admet-1586	50	9	or	or	CCONJ
admet-1586	50	10	hpmcas	hpmca	NOUN
admet-1586	50	11	-	-	PUNCT
admet-1586	50	12	mx	mx	NOUN
admet-1586	50	13	at	at	ADP
admet-1586	50	14	a	a	DET
admet-1586	50	15	20:80	20:80	NUM
admet-1586	50	16	ratio	ratio	NOUN
admet-1586	50	17	were	be	AUX
admet-1586	50	18	prepared	prepare	VERB
admet-1586	50	19	using	use	VERB
admet-1586	50	20	a	a	DET
admet-1586	50	21	mortar	mortar	NOUN
admet-1586	50	22	and	and	CCONJ
admet-1586	50	23	pestle	pestle	NOUN
admet-1586	50	24	and	and	CCONJ
admet-1586	50	25	10	10	NUM
admet-1586	50	26	g	g	NOUN
admet-1586	50	27	of	of	ADP
admet-1586	50	28	each	each	DET
admet-1586	50	29	physical	physical	ADJ
admet-1586	50	30	mixture	mixture	NOUN
admet-1586	50	31	was	be	AUX
admet-1586	50	32	subjected	subject	VERB
admet-1586	50	33	into	into	ADP
admet-1586	50	34	a	a	DET
admet-1586	50	35	feeder	feeder	NOUN
admet-1586	50	36	of	of	ADP
admet-1586	50	37	the	the	DET
admet-1586	50	38	hot	hot	ADJ
admet-1586	50	39	-	-	PUNCT
admet-1586	50	40	melt	melt	NOUN
admet-1586	50	41	extrusion	extrusion	NOUN
admet-1586	50	42	apparatus	apparatus	NOUN
admet-1586	50	43	followed	follow	VERB
admet-1586	50	44	by	by	ADP
admet-1586	50	45	mixing	mix	VERB
admet-1586	50	46	with	with	ADP
admet-1586	50	47	twin	twin	ADJ
admet-1586	50	48	-	-	PUNCT
admet-1586	50	49	screw	screw	NOUN
admet-1586	50	50	rotation	rotation	NOUN
admet-1586	50	51	at	at	ADP
admet-1586	50	52	20	20	NUM
admet-1586	50	53	rpm	rpm	NOUN
admet-1586	50	54	.	.	PUNCT
admet-1586	51	1	both	both	DET
admet-1586	51	2	carriers	carrier	NOUN
admet-1586	51	3	showed	show	VERB
admet-1586	51	4	no	no	DET
admet-1586	51	5	thermal	thermal	ADJ
admet-1586	51	6	degradation	degradation	NOUN
admet-1586	51	7	up	up	ADP
admet-1586	51	8	to	to	PART
admet-1586	51	9	250	250	NUM
admet-1586	51	10	°	°	NOUN
admet-1586	52	1	c	c	NOUN
admet-1586	53	1	[	[	X
admet-1586	53	2	19	19	NUM
admet-1586	53	3	]	]	PUNCT
admet-1586	53	4	,	,	PUNCT
admet-1586	53	5	therefore	therefore	ADV
admet-1586	53	6	,	,	PUNCT
admet-1586	53	7	the	the	DET
admet-1586	53	8	preparation	preparation	NOUN
admet-1586	53	9	temperature	temperature	NOUN
admet-1586	53	10	was	be	AUX
admet-1586	53	11	set	set	VERB
admet-1586	53	12	to	to	PART
admet-1586	53	13	be	be	AUX
admet-1586	53	14	under	under	ADP
admet-1586	53	15	250	250	NUM
admet-1586	53	16	°	°	NOUN
admet-1586	53	17	c	c	NOUN
admet-1586	53	18	.	.	PUNCT
admet-1586	54	1	the	the	DET
admet-1586	54	2	hme	hme	PROPN
admet-1586	54	3	experiment	experiment	NOUN
admet-1586	54	4	was	be	AUX
admet-1586	54	5	performed	perform	VERB
admet-1586	54	6	to	to	PART
admet-1586	54	7	confirm	confirm	VERB
admet-1586	54	8	the	the	DET
admet-1586	54	9	appropriate	appropriate	ADJ
admet-1586	54	10	temperature	temperature	NOUN
admet-1586	54	11	for	for	ADP
admet-1586	54	12	the	the	DET
admet-1586	54	13	process	process	NOUN
admet-1586	54	14	.	.	PUNCT
admet-1586	55	1	subsequently	subsequently	ADV
admet-1586	55	2	,	,	PUNCT
admet-1586	55	3	the	the	DET
admet-1586	55	4	temperature	temperature	NOUN
admet-1586	55	5	was	be	AUX
admet-1586	55	6	set	set	VERB
admet-1586	55	7	at	at	ADP
admet-1586	55	8	100	100	NUM
admet-1586	55	9	°	°	NOUN
admet-1586	55	10	c	c	NOUN
admet-1586	55	11	,	,	PUNCT
admet-1586	55	12	and	and	CCONJ
admet-1586	55	13	the	the	DET
admet-1586	55	14	mixture	mixture	NOUN
admet-1586	55	15	was	be	AUX
admet-1586	55	16	processed	process	VERB
admet-1586	55	17	for	for	ADP
admet-1586	55	18	10	10	NUM
admet-1586	55	19	min	min	NOUN
admet-1586	55	20	.	.	PUNCT
admet-1586	56	1	the	the	DET
admet-1586	56	2	temperature	temperature	NOUN
admet-1586	56	3	was	be	AUX
admet-1586	56	4	raised	raise	VERB
admet-1586	56	5	in	in	ADP
admet-1586	56	6	increments	increment	NOUN
admet-1586	56	7	of	of	ADP
admet-1586	56	8	10	10	NUM
admet-1586	56	9	°	°	NOUN
admet-1586	56	10	c	c	NOUN
admet-1586	56	11	from	from	ADP
admet-1586	56	12	100	100	NUM
admet-1586	56	13	to	to	PART
admet-1586	56	14	170	170	NUM
admet-1586	57	1	°	°	NOUN
admet-1586	57	2	c	c	NOUN
admet-1586	57	3	;	;	PUNCT
admet-1586	57	4	the	the	DET
admet-1586	57	5	hme	hme	NOUN
admet-1586	57	6	process	process	NOUN
admet-1586	57	7	was	be	AUX
admet-1586	57	8	conducted	conduct	VERB
admet-1586	57	9	for	for	ADP
admet-1586	57	10	10	10	NUM
admet-1586	57	11	min	min	NOUN
admet-1586	57	12	at	at	ADP
admet-1586	57	13	each	each	DET
admet-1586	57	14	temperature	temperature	NOUN
admet-1586	57	15	.	.	PUNCT
admet-1586	58	1	the	the	DET
admet-1586	58	2	solid	solid	ADJ
admet-1586	58	3	dispersion	dispersion	NOUN
admet-1586	58	4	samples	sample	NOUN
admet-1586	58	5	prepared	prepare	VERB
admet-1586	58	6	at	at	ADP
admet-1586	58	7	170	170	NUM
admet-1586	58	8	°	°	NOUN
admet-1586	58	9	c	c	NOUN
admet-1586	58	10	were	be	AUX
admet-1586	58	11	used	use	VERB
admet-1586	58	12	for	for	ADP
admet-1586	58	13	the	the	DET
admet-1586	58	14	physiochemical	physiochemical	ADJ
admet-1586	58	15	and	and	CCONJ
admet-1586	58	16	dissolution	dissolution	ADJ
admet-1586	58	17	-	-	PUNCT
admet-1586	58	18	permeation	permeation	NOUN
admet-1586	58	19	studies	study	NOUN
admet-1586	58	20	because	because	SCONJ
admet-1586	58	21	the	the	DET
admet-1586	58	22	formulations	formulation	NOUN
admet-1586	58	23	showed	show	VERB
admet-1586	58	24	amorphization	amorphization	NOUN
admet-1586	58	25	at	at	ADP
admet-1586	58	26	this	this	DET
admet-1586	58	27	temperature	temperature	NOUN
admet-1586	58	28	.	.	PUNCT
admet-1586	59	1	extruder	extruder	NOUN
admet-1586	59	2	torque	torque	NOUN
admet-1586	59	3	readings	reading	NOUN
admet-1586	59	4	were	be	AUX
admet-1586	59	5	recorded	record	VERB
admet-1586	59	6	for	for	ADP
admet-1586	59	7	each	each	DET
admet-1586	59	8	temperature	temperature	NOUN
admet-1586	59	9	after	after	ADP
admet-1586	59	10	each	each	DET
admet-1586	59	11	10	10	NUM
admet-1586	59	12	-	-	PUNCT
admet-1586	59	13	min	min	NOUN
admet-1586	59	14	process	process	NOUN
admet-1586	59	15	.	.	PUNCT
admet-1586	60	1	the	the	DET
admet-1586	60	2	hot	hot	ADJ
admet-1586	60	3	-	-	PUNCT
admet-1586	60	4	melt	melt	NOUN
admet-1586	60	5	extruded	extruded	NOUN
admet-1586	60	6	was	be	AUX
admet-1586	60	7	milled	mill	VERB
admet-1586	60	8	using	use	VERB
admet-1586	60	9	a	a	DET
admet-1586	60	10	tablet	tablet	NOUN
admet-1586	60	11	mill	mill	NOUN
admet-1586	60	12	jf-001j1	jf-001j1	PROPN
admet-1586	60	13	(	(	PUNCT
admet-1586	60	14	takazono	takazono	NOUN
admet-1586	60	15	corporation	corporation	NOUN
admet-1586	60	16	.	.	PUNCT
admet-1586	61	1	,	,	PUNCT
admet-1586	61	2	tokyo	tokyo	PROPN
admet-1586	61	3	,	,	PUNCT
admet-1586	61	4	japan	japan	PROPN
admet-1586	61	5	)	)	PUNCT
admet-1586	62	1	at	at	ADP
admet-1586	62	2	around	around	ADV
admet-1586	62	3	15,000	15,000	NUM
admet-1586	62	4	rpm	rpm	NOUN
admet-1586	62	5	for	for	ADP
admet-1586	62	6	1	1	NUM
admet-1586	62	7	min	min	NOUN
admet-1586	62	8	.	.	PUNCT
admet-1586	62	9	the	the	DET
admet-1586	62	10	resulting	result	VERB
admet-1586	62	11	powders	powder	NOUN
admet-1586	62	12	were	be	AUX
admet-1586	62	13	treated	treat	VERB
admet-1586	62	14	as	as	ADP
admet-1586	62	15	solid	solid	ADJ
admet-1586	62	16	dispersion	dispersion	NOUN
admet-1586	62	17	samples	sample	NOUN
admet-1586	62	18	.	.	PUNCT
admet-1586	63	1	the	the	DET
admet-1586	63	2	sample	sample	NOUN
admet-1586	63	3	comprising	comprise	VERB
admet-1586	63	4	20	20	NUM
admet-1586	63	5	%	%	NOUN
admet-1586	63	6	imc	imc	NOUN
admet-1586	63	7	and	and	CCONJ
admet-1586	63	8	80	80	NUM
admet-1586	63	9	%	%	NOUN
admet-1586	63	10	hpmcas	hpmca	NOUN
admet-1586	63	11	-	-	PUNCT
admet-1586	63	12	mg	mg	PROPN
admet-1586	63	13	(	(	PUNCT
admet-1586	63	14	or	or	CCONJ
admet-1586	63	15	-mx	-mx	PROPN
admet-1586	63	16	)	)	PUNCT
admet-1586	63	17	is	be	AUX
admet-1586	63	18	termed	term	VERB
admet-1586	63	19	imcmg	imcmg	NOUN
admet-1586	63	20	(	(	PUNCT
admet-1586	63	21	or	or	CCONJ
admet-1586	63	22	-mx	-mx	ADP
admet-1586	63	23	)	)	PUNCT
admet-1586	63	24	(	(	PUNCT
admet-1586	63	25	20:80	20:80	NUM
admet-1586	63	26	)	)	PUNCT
admet-1586	63	27	in	in	ADP
admet-1586	63	28	the	the	DET
admet-1586	63	29	current	current	ADJ
admet-1586	63	30	study	study	NOUN
admet-1586	63	31	.	.	PUNCT
admet-1586	64	1	scanning	scan	VERB
admet-1586	64	2	electron	electron	NOUN
admet-1586	64	3	microscope	microscope	NOUN
admet-1586	64	4	(	(	PUNCT
admet-1586	64	5	sem	sem	NOUN
admet-1586	64	6	)	)	PUNCT
admet-1586	64	7	the	the	DET
admet-1586	64	8	hot	hot	ADJ
admet-1586	64	9	-	-	PUNCT
admet-1586	64	10	melt	melt	NOUN
admet-1586	64	11	extruded	extrude	VERB
admet-1586	64	12	samples	sample	NOUN
admet-1586	64	13	prepared	prepare	VERB
admet-1586	64	14	at	at	ADP
admet-1586	64	15	170	170	NUM
admet-1586	64	16	°	°	NOUN
admet-1586	64	17	c	c	NOUN
admet-1586	64	18	were	be	AUX
admet-1586	64	19	glued	glue	VERB
admet-1586	64	20	on	on	ADP
admet-1586	64	21	12	12	NUM
admet-1586	64	22	mm	mm	NOUN
admet-1586	64	23	diameter	diameter	NOUN
admet-1586	64	24	aluminum	aluminum	PROPN
admet-1586	64	25	sample	sample	NOUN
admet-1586	64	26	holders	holder	NOUN
admet-1586	64	27	using	use	VERB
admet-1586	64	28	a	a	DET
admet-1586	64	29	round	round	ADJ
admet-1586	64	30	carbon	carbon	NOUN
admet-1586	64	31	seal	seal	NOUN
admet-1586	64	32	(	(	PUNCT
admet-1586	64	33	nisshin	nisshin	VERB
admet-1586	64	34	em	em	PROPN
admet-1586	64	35	co.	co.	PROPN
admet-1586	64	36	,	,	PUNCT
admet-1586	64	37	ltd	ltd	PROPN
admet-1586	64	38	.	.	PROPN
admet-1586	64	39	,	,	PUNCT
admet-1586	64	40	tokyo	tokyo	PROPN
admet-1586	64	41	,	,	PUNCT
admet-1586	64	42	japan	japan	PROPN
admet-1586	64	43	)	)	PUNCT
admet-1586	64	44	.	.	PUNCT
admet-1586	65	1	the	the	DET
admet-1586	65	2	samples	sample	NOUN
admet-1586	65	3	were	be	AUX
admet-1586	65	4	sputter	sputter	VERB
admet-1586	65	5	-	-	ADJ
admet-1586	65	6	coated	coated	ADJ
admet-1586	65	7	with	with	ADP
admet-1586	65	8	an	an	DET
admet-1586	65	9	au	au	ADJ
admet-1586	65	10	alloy	alloy	NOUN
admet-1586	65	11	using	use	VERB
admet-1586	65	12	a	a	DET
admet-1586	65	13	magnetron	magnetron	ADJ
admet-1586	65	14	sputter	sputter	NOUN
admet-1586	65	15	(	(	PUNCT
admet-1586	65	16	msp-1s	msp-1s	NOUN
admet-1586	65	17	,	,	PUNCT
admet-1586	65	18	vacuum	vacuum	NOUN
admet-1586	65	19	device	device	NOUN
admet-1586	65	20	,	,	PUNCT
admet-1586	65	21	ibaraki	ibaraki	NOUN
admet-1586	65	22	,	,	PUNCT
admet-1586	65	23	japan	japan	PROPN
admet-1586	65	24	)	)	PUNCT
admet-1586	65	25	.	.	PUNCT
admet-1586	66	1	the	the	DET
admet-1586	66	2	shapes	shape	NOUN
admet-1586	66	3	and	and	CCONJ
admet-1586	66	4	surface	surface	NOUN
admet-1586	66	5	morphologies	morphology	NOUN
admet-1586	66	6	of	of	ADP
admet-1586	66	7	samples	sample	NOUN
admet-1586	66	8	were	be	AUX
admet-1586	66	9	investigated	investigate	VERB
admet-1586	66	10	using	use	VERB
admet-1586	66	11	an	an	DET
admet-1586	66	12	sem	sem	NOUN
admet-1586	66	13	(	(	PUNCT
admet-1586	66	14	ve-8800	ve-8800	ADJ
admet-1586	66	15	,	,	PUNCT
admet-1586	66	16	keyence	keyence	NOUN
admet-1586	66	17	corporation	corporation	NOUN
admet-1586	66	18	,	,	PUNCT
admet-1586	66	19	osaka	osaka	PROPN
admet-1586	66	20	,	,	PUNCT
admet-1586	66	21	japan	japan	PROPN
admet-1586	66	22	)	)	PUNCT
admet-1586	66	23	.	.	PUNCT
admet-1586	67	1	raman	raman	NOUN
admet-1586	67	2	mapping	mapping	NOUN
admet-1586	67	3	to	to	PART
admet-1586	67	4	measure	measure	VERB
admet-1586	67	5	the	the	DET
admet-1586	67	6	amorphization	amorphization	NOUN
admet-1586	67	7	and	and	CCONJ
admet-1586	67	8	distribution	distribution	NOUN
admet-1586	67	9	of	of	ADP
admet-1586	67	10	imc	imc	NOUN
admet-1586	67	11	into	into	ADP
admet-1586	67	12	the	the	DET
admet-1586	67	13	carrier	carrier	NOUN
admet-1586	67	14	non	non	ADJ
admet-1586	67	15	-	-	ADJ
admet-1586	67	16	destructively	destructively	ADV
admet-1586	67	17	,	,	PUNCT
admet-1586	67	18	raman	raman	ADJ
admet-1586	67	19	imaging	imaging	NOUN
admet-1586	67	20	was	be	AUX
admet-1586	67	21	performed	perform	VERB
admet-1586	67	22	for	for	ADP
admet-1586	67	23	the	the	DET
admet-1586	67	24	hot	hot	ADJ
admet-1586	67	25	-	-	PUNCT
admet-1586	67	26	melt	melt	NOUN
admet-1586	67	27	extruded	extrude	VERB
admet-1586	67	28	samples	sample	NOUN
admet-1586	67	29	prepared	prepare	VERB
admet-1586	67	30	at	at	ADP
admet-1586	67	31	120	120	NUM
admet-1586	67	32	and	and	CCONJ
admet-1586	67	33	170	170	NUM
admet-1586	67	34	°	°	NOUN
admet-1586	67	35	c	c	VERB
admet-1586	67	36	.	.	PUNCT
admet-1586	68	1	the	the	DET
admet-1586	68	2	raman	raman	ADJ
admet-1586	68	3	spectra	spectra	NOUN
admet-1586	68	4	of	of	ADP
admet-1586	68	5	crystalline	crystalline	NOUN
admet-1586	68	6	and	and	CCONJ
admet-1586	68	7	amorphous	amorphous	ADJ
admet-1586	68	8	imc	imc	PROPN
admet-1586	68	9	were	be	AUX
admet-1586	68	10	measured	measure	VERB
admet-1586	68	11	using	use	VERB
admet-1586	68	12	a	a	DET
admet-1586	68	13	ramantouch	ramantouch	NOUN
admet-1586	68	14	laser	laser	NOUN
admet-1586	68	15	raman	raman	NOUN
admet-1586	68	16	microscope	microscope	NOUN
admet-1586	68	17	(	(	PUNCT
admet-1586	68	18	nanophoton	nanophoton	PROPN
admet-1586	68	19	corporation	corporation	PROPN
admet-1586	68	20	,	,	PUNCT
admet-1586	68	21	osaka	osaka	PROPN
admet-1586	68	22	,	,	PUNCT
admet-1586	68	23	japan	japan	PROPN
admet-1586	68	24	)	)	PUNCT
admet-1586	68	25	.	.	PUNCT
admet-1586	69	1	the	the	DET
admet-1586	69	2	samples	sample	NOUN
admet-1586	69	3	were	be	AUX
admet-1586	69	4	placed	place	VERB
admet-1586	69	5	onto	onto	ADP
admet-1586	69	6	a	a	DET
admet-1586	69	7	hole	hole	NOUN
admet-1586	69	8	(	(	PUNCT
admet-1586	69	9	diameter	diameter	NOUN
admet-1586	69	10	:	:	PUNCT
admet-1586	69	11	3	3	NUM
admet-1586	69	12	mm	mm	NOUN
admet-1586	69	13	and	and	CCONJ
admet-1586	69	14	depth	depth	NOUN
admet-1586	69	15	:	:	PUNCT
admet-1586	69	16	0.2	0.2	NUM
admet-1586	69	17	mm	mm	NOUN
admet-1586	69	18	)	)	PUNCT
admet-1586	69	19	on	on	ADP
admet-1586	69	20	an	an	DET
admet-1586	69	21	aluminum	aluminum	NOUN
admet-1586	69	22	plate	plate	NOUN
admet-1586	69	23	,	,	PUNCT
admet-1586	69	24	followed	follow	VERB
admet-1586	69	25	by	by	ADP
admet-1586	69	26	smoothing	smooth	VERB
admet-1586	69	27	of	of	ADP
admet-1586	69	28	the	the	DET
admet-1586	69	29	surface	surface	NOUN
admet-1586	69	30	using	use	VERB
admet-1586	69	31	a	a	DET
admet-1586	69	32	spatula	spatula	NOUN
admet-1586	69	33	.	.	PUNCT
admet-1586	70	1	raman	raman	NOUN
admet-1586	70	2	spectroscopic	spectroscopic	NOUN
admet-1586	70	3	measurement	measurement	NOUN
admet-1586	70	4	was	be	AUX
admet-1586	70	5	performed	perform	VERB
admet-1586	70	6	in	in	ADP
admet-1586	70	7	the	the	DET
admet-1586	70	8	carbonyl	carbonyl	NOUN
admet-1586	70	9	region	region	NOUN
admet-1586	70	10	between	between	ADP
admet-1586	70	11	1800	1800	NUM
admet-1586	70	12	-	-	SYM
admet-1586	70	13	1500	1500	NUM
admet-1586	70	14	cm−1	cm−1	NOUN
admet-1586	70	15	.	.	PUNCT
admet-1586	71	1	the	the	DET
admet-1586	71	2	procedure	procedure	NOUN
admet-1586	71	3	and	and	CCONJ
admet-1586	71	4	the	the	DET
admet-1586	71	5	conditions	condition	NOUN
admet-1586	71	6	of	of	ADP
admet-1586	71	7	the	the	DET
admet-1586	71	8	apparatus	apparatus	NOUN
admet-1586	71	9	were	be	AUX
admet-1586	71	10	set	set	VERB
admet-1586	71	11	according	accord	VERB
admet-1586	71	12	to	to	ADP
admet-1586	71	13	a	a	DET
admet-1586	71	14	previous	previous	ADJ
admet-1586	71	15	study	study	NOUN
admet-1586	71	16	[	[	X
admet-1586	71	17	19	19	NUM
admet-1586	71	18	]	]	X
admet-1586	71	19	:	:	PUNCT
admet-1586	71	20	excitation	excitation	NOUN
admet-1586	71	21	wavelength	wavelength	NOUN
admet-1586	71	22	785.16	785.16	NUM
admet-1586	71	23	nm	nm	NOUN
admet-1586	71	24	,	,	PUNCT
admet-1586	71	25	excitation	excitation	NOUN
admet-1586	71	26	power	power	NOUN
admet-1586	71	27	113.04	113.04	NUM
admet-1586	71	28	mw	mw	NOUN
admet-1586	71	29	,	,	PUNCT
admet-1586	71	30	nd	nd	PRON
admet-1586	71	31	filter	filter	VERB
admet-1586	71	32	100	100	NUM
admet-1586	71	33	%	%	NOUN
admet-1586	71	34	,	,	PUNCT
admet-1586	71	35	spectrograph	spectrograph	NOUN
admet-1586	71	36	center	center	NOUN
admet-1586	71	37	wavelength	wavelength	NOUN
admet-1586	71	38	1400	1400	NUM
admet-1586	71	39	cm−1	cm−1	NOUN
admet-1586	71	40	,	,	PUNCT
admet-1586	71	41	grating	grate	VERB
admet-1586	71	42	600	600	NUM
admet-1586	71	43	gr	gr	NOUN
admet-1586	71	44	mm-1	mm-1	NOUN
admet-1586	71	45	,	,	PUNCT
admet-1586	71	46	slit	slit	NOUN
admet-1586	71	47	width	width	VERB
admet-1586	71	48	50	50	NUM
admet-1586	71	49	µm	µm	NOUN
admet-1586	71	50	,	,	PUNCT
admet-1586	71	51	exposure	exposure	NOUN
admet-1586	71	52	time	time	NOUN
admet-1586	71	53	3	3	NUM
admet-1586	71	54	s	s	NOUN
admet-1586	71	55	,	,	PUNCT
admet-1586	71	56	averaging	average	VERB
admet-1586	71	57	1	1	NUM
admet-1586	71	58	,	,	PUNCT
admet-1586	71	59	gain	gain	VERB
admet-1586	71	60	high	high	ADJ
admet-1586	71	61	,	,	PUNCT
admet-1586	71	62	readout	readout	VERB
admet-1586	71	63	port	port	NOUN
admet-1586	71	64	low	low	ADJ
admet-1586	71	65	noise	noise	NOUN
admet-1586	71	66	,	,	PUNCT
admet-1586	71	67	readout	readout	VERB
admet-1586	71	68	speed	speed	NOUN
admet-1586	71	69	2	2	NUM
admet-1586	71	70	mhz	mhz	NOUN
admet-1586	71	71	,	,	PUNCT
admet-1586	71	72	ccd	ccd	NOUN
admet-1586	71	73	temperature	temperature	NOUN
admet-1586	71	74	−70	−70	NOUN
admet-1586	71	75	°	°	ADP
admet-1586	71	76	c	c	NOUN
admet-1586	71	77	,	,	PUNCT
admet-1586	71	78	and	and	CCONJ
admet-1586	71	79	objective	objective	ADJ
admet-1586	71	80	lens	lens	NOUN
admet-1586	71	81	10×/na	10×/na	NUM
admet-1586	71	82	0.3	0.3	NUM
admet-1586	71	83	.	.	PUNCT
admet-1586	72	1	the	the	DET
admet-1586	72	2	wavenumber	wavenumber	NOUN
admet-1586	72	3	was	be	AUX
admet-1586	72	4	calibrated	calibrate	VERB
admet-1586	72	5	using	use	VERB
admet-1586	72	6	a	a	DET
admet-1586	72	7	spectrum	spectrum	NOUN
admet-1586	72	8	of	of	ADP
admet-1586	72	9	silicon	silicon	NOUN
admet-1586	72	10	provided	provide	VERB
admet-1586	72	11	by	by	ADP
admet-1586	72	12	the	the	DET
admet-1586	72	13	equipment	equipment	NOUN
admet-1586	72	14	.	.	PUNCT
admet-1586	73	1	an	an	DET
admet-1586	73	2	area	area	NOUN
admet-1586	73	3	of	of	ADP
admet-1586	73	4	the	the	DET
admet-1586	73	5	solid	solid	ADJ
admet-1586	73	6	dispersions	dispersion	NOUN
admet-1586	73	7	measuring	measure	VERB
admet-1586	73	8	200×200	200×200	NUM
admet-1586	73	9	μm	μm	NOUN
admet-1586	73	10	was	be	AUX
admet-1586	73	11	evaluated	evaluate	VERB
admet-1586	73	12	at	at	ADP
admet-1586	73	13	a	a	DET
admet-1586	73	14	resolution	resolution	NOUN
admet-1586	73	15	of	of	ADP
admet-1586	73	16	2000	2000	NUM
admet-1586	73	17	nm	nm	NOUN
admet-1586	73	18	per	per	ADP
admet-1586	73	19	spot	spot	NOUN
admet-1586	73	20	using	use	VERB
admet-1586	73	21	raman	raman	NOUN
admet-1586	73	22	imager	imager	NOUN
admet-1586	73	23	2	2	NUM
admet-1586	73	24	(	(	PUNCT
admet-1586	73	25	nanophoton	nanophoton	PROPN
admet-1586	73	26	corporation	corporation	NOUN
admet-1586	73	27	,	,	PUNCT
admet-1586	73	28	osaka	osaka	PROPN
admet-1586	73	29	,	,	PUNCT
admet-1586	73	30	japan	japan	PROPN
admet-1586	73	31	)	)	PUNCT
admet-1586	73	32	.	.	PUNCT
admet-1586	74	1	the	the	DET
admet-1586	74	2	raman	raman	NOUN
admet-1586	74	3	image	image	NOUN
admet-1586	74	4	was	be	AUX
admet-1586	74	5	drawn	draw	VERB
admet-1586	74	6	by	by	ADP
admet-1586	74	7	the	the	DET
admet-1586	74	8	peak	peak	NOUN
admet-1586	74	9	ratio	ratio	NOUN
admet-1586	74	10	of	of	ADP
admet-1586	74	11	the	the	DET
admet-1586	74	12	crystalline	crystalline	NOUN
admet-1586	74	13	and	and	CCONJ
admet-1586	74	14	the	the	DET
admet-1586	74	15	amorphous	amorphous	ADJ
admet-1586	74	16	imc	imc	PROPN
admet-1586	74	17	;	;	PUNCT
admet-1586	74	18	the	the	DET
admet-1586	74	19	ranges	range	NOUN
admet-1586	74	20	of	of	ADP
admet-1586	74	21	1699.8	1699.8	NUM
admet-1586	74	22	to	to	ADP
admet-1586	74	23	1700.5	1700.5	NUM
admet-1586	74	24	cm−1	cm−1	NOUN
admet-1586	74	25	and	and	CCONJ
admet-1586	74	26	1685.1	1685.1	NUM
admet-1586	74	27	to	to	ADP
admet-1586	74	28	1695.8	1695.8	NUM
admet-1586	74	29	cm−1	cm−1	NOUN
admet-1586	74	30	were	be	AUX
admet-1586	74	31	used	use	VERB
admet-1586	74	32	as	as	ADP
admet-1586	74	33	the	the	DET
admet-1586	74	34	peak	peak	NOUN
admet-1586	74	35	areas	area	NOUN
admet-1586	74	36	of	of	ADP
admet-1586	74	37	the	the	DET
admet-1586	74	38	crystalline	crystalline	NOUN
admet-1586	74	39	and	and	CCONJ
admet-1586	74	40	the	the	DET
admet-1586	74	41	amorphous	amorphous	ADJ
admet-1586	74	42	imc	imc	PROPN
admet-1586	74	43	,	,	PUNCT
admet-1586	74	44	respectively	respectively	ADV
admet-1586	74	45	.	.	PUNCT
admet-1586	75	1	x	x	X
admet-1586	75	2	-	-	PUNCT
admet-1586	75	3	ray	ray	NOUN
admet-1586	75	4	powder	powder	NOUN
admet-1586	75	5	diffraction	diffraction	NOUN
admet-1586	75	6	amorphization	amorphization	NOUN
admet-1586	75	7	of	of	ADP
admet-1586	75	8	the	the	DET
admet-1586	75	9	hot	hot	ADJ
admet-1586	75	10	-	-	PUNCT
admet-1586	75	11	melt	melt	NOUN
admet-1586	75	12	extruded	extrude	VERB
admet-1586	75	13	samples	sample	NOUN
admet-1586	75	14	was	be	AUX
admet-1586	75	15	measured	measure	VERB
admet-1586	75	16	by	by	ADP
admet-1586	75	17	x	x	NOUN
admet-1586	75	18	-	-	NOUN
admet-1586	75	19	ray	ray	NOUN
admet-1586	75	20	powder	powder	NOUN
admet-1586	75	21	diffraction	diffraction	NOUN
admet-1586	75	22	(	(	PUNCT
admet-1586	75	23	xrpd	xrpd	ADJ
admet-1586	75	24	)	)	PUNCT
admet-1586	75	25	.	.	PUNCT
admet-1586	76	1	the	the	DET
admet-1586	76	2	smooth	smooth	ADJ
admet-1586	76	3	samples	sample	NOUN
admet-1586	76	4	were	be	AUX
admet-1586	76	5	placed	place	VERB
admet-1586	76	6	on	on	ADP
admet-1586	76	7	an	an	DET
admet-1586	76	8	aluminum	aluminum	NOUN
admet-1586	76	9	plate	plate	NOUN
admet-1586	76	10	with	with	ADP
admet-1586	76	11	holes	hole	NOUN
admet-1586	76	12	(	(	PUNCT
admet-1586	76	13	diameter	diameter	NOUN
admet-1586	76	14	=	=	SYM
admet-1586	76	15	2	2	NUM
admet-1586	76	16	mm	mm	NOUN
admet-1586	76	17	,	,	PUNCT
admet-1586	76	18	depth	depth	NOUN
admet-1586	76	19	=	=	NOUN
admet-1586	76	20	0.1	0.1	NUM
admet-1586	76	21	mm	mm	NOUN
admet-1586	76	22	)	)	PUNCT
admet-1586	76	23	and	and	CCONJ
admet-1586	76	24	analyzed	analyze	VERB
admet-1586	76	25	with	with	ADP
admet-1586	76	26	a	a	DET
admet-1586	76	27	smartlab	smartlab	NOUN
admet-1586	76	28	(	(	PUNCT
admet-1586	76	29	rigaku	rigaku	NOUN
admet-1586	76	30	corporation	corporation	NOUN
admet-1586	76	31	,	,	PUNCT
admet-1586	76	32	tokyo	tokyo	PROPN
admet-1586	76	33	,	,	PUNCT
admet-1586	76	34	japan	japan	PROPN
admet-1586	76	35	)	)	PUNCT
admet-1586	76	36	instrument	instrument	NOUN
admet-1586	76	37	equipped	equip	VERB
admet-1586	76	38	with	with	ADP
admet-1586	76	39	a	a	DET
admet-1586	76	40	9	9	NUM
admet-1586	76	41	kw	kw	NOUN
admet-1586	76	42	rotating	rotate	VERB
admet-1586	76	43	anode	anode	NOUN
admet-1586	76	44	using	use	VERB
admet-1586	76	45	cu	cu	PROPN
admet-1586	76	46	kα	kα	PROPN
admet-1586	76	47	radiation	radiation	NOUN
admet-1586	76	48	(	(	PUNCT
admet-1586	76	49	λ	λ	X
admet-1586	76	50	=	=	NOUN
admet-1586	76	51	0.154186	0.154186	NUM
admet-1586	76	52	nm	nm	NOUN
admet-1586	76	53	)	)	PUNCT
admet-1586	76	54	and	and	CCONJ
admet-1586	76	55	a	a	DET
admet-1586	76	56	hypix-3000	hypix-3000	ADJ
admet-1586	76	57	detector	detector	NOUN
admet-1586	76	58	.	.	PUNCT
admet-1586	77	1	the	the	DET
admet-1586	77	2	distance	distance	NOUN
admet-1586	77	3	between	between	ADP
admet-1586	77	4	the	the	DET
admet-1586	77	5	sample	sample	NOUN
admet-1586	77	6	and	and	CCONJ
admet-1586	77	7	detector	detector	NOUN
admet-1586	77	8	was	be	AUX
admet-1586	77	9	331	331	NUM
admet-1586	77	10	mm	mm	NOUN
admet-1586	77	11	;	;	PUNCT
admet-1586	77	12	the	the	DET
admet-1586	77	13	diffractometer	diffractometer	NOUN
admet-1586	77	14	was	be	AUX
admet-1586	77	15	equipped	equip	VERB
admet-1586	77	16	with	with	ADP
admet-1586	77	17	a	a	DET
admet-1586	77	18	cross	cross	ADJ
admet-1586	77	19	-	-	ADJ
admet-1586	77	20	beam	beam	ADJ
admet-1586	77	21	optic	optic	NOUN
admet-1586	77	22	,	,	PUNCT
admet-1586	77	23	providing	provide	VERB
admet-1586	77	24	a	a	DET
admet-1586	77	25	parallel	parallel	NOUN
admet-1586	77	26	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	NOUN
admet-1586	77	27	h.	h.	PROPN
admet-1586	77	28	tanaka	tanaka	PROPN
admet-1586	77	29	et	et	PROPN
admet-1586	77	30	al	al	PROPN
admet-1586	77	31	.	.	PROPN
admet-1586	77	32	admet	admet	PROPN
admet-1586	77	33	&	&	CCONJ
admet-1586	77	34	dmpk	dmpk	PROPN
admet-1586	77	35	11(3	11(3	NUM
admet-1586	77	36	)	)	PUNCT
admet-1586	77	37	(	(	PUNCT
admet-1586	77	38	2023	2023	NUM
admet-1586	77	39	)	)	PUNCT
admet-1586	77	40	373	373	NUM
admet-1586	77	41	-	-	SYM
admet-1586	77	42	385	385	NUM
admet-1586	77	43	376	376	NUM
admet-1586	77	44	beam	beam	NOUN
admet-1586	77	45	.	.	PUNCT
admet-1586	78	1	a	a	DET
admet-1586	78	2	psc	psc	NOUN
admet-1586	78	3	with	with	ADP
admet-1586	78	4	2.5	2.5	NUM
admet-1586	78	5	°	°	NOUN
admet-1586	78	6	and	and	CCONJ
admet-1586	78	7	a	a	DET
admet-1586	78	8	slit	slit	NOUN
admet-1586	78	9	of	of	ADP
admet-1586	78	10	0.05	0.05	NUM
admet-1586	78	11	mm	mm	NOUN
admet-1586	78	12	height	height	NOUN
admet-1586	78	13	and	and	CCONJ
admet-1586	78	14	0.5	0.5	NUM
admet-1586	78	15	mm	mm	NOUN
admet-1586	78	16	width	width	NOUN
admet-1586	78	17	was	be	AUX
admet-1586	78	18	used	use	VERB
admet-1586	78	19	;	;	PUNCT
admet-1586	78	20	thus	thus	ADV
admet-1586	78	21	,	,	PUNCT
admet-1586	78	22	the	the	DET
admet-1586	78	23	beam	beam	NOUN
admet-1586	78	24	footprint	footprint	NOUN
admet-1586	78	25	for	for	ADP
admet-1586	78	26	all	all	DET
admet-1586	78	27	measurement	measurement	NOUN
admet-1586	78	28	configurations	configuration	NOUN
admet-1586	78	29	was	be	AUX
admet-1586	78	30	smaller	small	ADJ
admet-1586	78	31	than	than	ADP
admet-1586	78	32	that	that	PRON
admet-1586	78	33	of	of	ADP
admet-1586	78	34	the	the	DET
admet-1586	78	35	sample	sample	NOUN
admet-1586	78	36	.	.	PUNCT
admet-1586	79	1	no	no	DET
admet-1586	79	2	slit	slit	NOUN
admet-1586	79	3	was	be	AUX
admet-1586	79	4	used	use	VERB
admet-1586	79	5	on	on	ADP
admet-1586	79	6	the	the	DET
admet-1586	79	7	receiving	receive	VERB
admet-1586	79	8	side	side	NOUN
admet-1586	79	9	.	.	PUNCT
admet-1586	80	1	the	the	DET
admet-1586	80	2	cu	cu	PROPN
admet-1586	80	3	kα	kα	PROPN
admet-1586	80	4	radiation	radiation	NOUN
admet-1586	80	5	point	point	NOUN
admet-1586	80	6	source	source	NOUN
admet-1586	80	7	was	be	AUX
admet-1586	80	8	operated	operate	VERB
admet-1586	80	9	at	at	ADP
admet-1586	80	10	40	40	NUM
admet-1586	80	11	kv	kv	PROPN
admet-1586	80	12	and	and	CCONJ
admet-1586	80	13	200	200	NUM
admet-1586	80	14	ma	ma	PROPN
admet-1586	80	15	.	.	PUNCT
admet-1586	81	1	the	the	DET
admet-1586	81	2	scan	scan	PROPN
admet-1586	81	3	was	be	AUX
admet-1586	81	4	performed	perform	VERB
admet-1586	81	5	from	from	ADP
admet-1586	81	6	2	2	NOUN
admet-1586	81	7	=	=	SYM
admet-1586	81	8	3	3	NUM
admet-1586	81	9	to	to	PART
admet-1586	81	10	32	32	NUM
admet-1586	81	11	°	°	NOUN
admet-1586	81	12	,	,	PUNCT
admet-1586	81	13	with	with	ADP
admet-1586	81	14			PROPN
admet-1586	81	15	axis	axis	NOUN
admet-1586	81	16	rotation	rotation	NOUN
admet-1586	81	17	(	(	PUNCT
admet-1586	81	18	20	20	NUM
admet-1586	81	19	rpm	rpm	NOUN
admet-1586	81	20	)	)	PUNCT
admet-1586	81	21	during	during	ADP
admet-1586	81	22	data	data	NOUN
admet-1586	81	23	collection	collection	NOUN
admet-1586	81	24	;	;	PUNCT
admet-1586	81	25	the	the	DET
admet-1586	81	26	sampling	sample	VERB
admet-1586	81	27	step	step	NOUN
admet-1586	81	28	was	be	AUX
admet-1586	81	29	2	2	NUM
admet-1586	81	30	=	=	SYM
admet-1586	81	31	0.02	0.02	NUM
admet-1586	81	32	°	°	NUM
admet-1586	81	33	,	,	PUNCT
admet-1586	81	34	and	and	CCONJ
admet-1586	81	35	the	the	DET
admet-1586	81	36	count	count	NOUN
admet-1586	81	37	time	time	NOUN
admet-1586	81	38	was	be	AUX
admet-1586	81	39	40	40	NUM
admet-1586	81	40	s.	s.	NOUN
admet-1586	81	41	the	the	DET
admet-1586	81	42	data	datum	NOUN
admet-1586	81	43	were	be	AUX
admet-1586	81	44	analyzed	analyze	VERB
admet-1586	81	45	using	use	VERB
admet-1586	81	46	smart	smart	ADJ
admet-1586	81	47	lab	lab	NOUN
admet-1586	81	48	studio	studio	PROPN
admet-1586	81	49	ii	ii	PROPN
admet-1586	81	50	x64	x64	PROPN
admet-1586	81	51	version	version	PROPN
admet-1586	81	52	4.2.111.0	4.2.111.0	PROPN
admet-1586	81	53	software	software	NOUN
admet-1586	81	54	(	(	PUNCT
admet-1586	81	55	rigaku	rigaku	NOUN
admet-1586	81	56	corporation	corporation	NOUN
admet-1586	81	57	,	,	PUNCT
admet-1586	81	58	tokyo	tokyo	PROPN
admet-1586	81	59	,	,	PUNCT
admet-1586	81	60	japan	japan	PROPN
admet-1586	81	61	)	)	PUNCT
admet-1586	81	62	.	.	PUNCT
admet-1586	82	1	physical	physical	ADJ
admet-1586	82	2	stability	stability	NOUN
admet-1586	82	3	the	the	DET
admet-1586	82	4	crystallization	crystallization	NOUN
admet-1586	82	5	tendency	tendency	NOUN
admet-1586	82	6	of	of	ADP
admet-1586	82	7	the	the	DET
admet-1586	82	8	solid	solid	ADJ
admet-1586	82	9	dispersion	dispersion	NOUN
admet-1586	82	10	samples	sample	NOUN
admet-1586	82	11	was	be	AUX
admet-1586	82	12	evaluated	evaluate	VERB
admet-1586	82	13	.	.	PUNCT
admet-1586	83	1	the	the	DET
admet-1586	83	2	samples	sample	NOUN
admet-1586	83	3	held	hold	VERB
admet-1586	83	4	on	on	ADP
admet-1586	83	5	a	a	DET
admet-1586	83	6	hole	hole	NOUN
admet-1586	83	7	(	(	PUNCT
admet-1586	83	8	diameter	diameter	NOUN
admet-1586	83	9	:	:	PUNCT
admet-1586	83	10	3	3	NUM
admet-1586	83	11	mm	mm	NOUN
admet-1586	83	12	and	and	CCONJ
admet-1586	83	13	depth	depth	NOUN
admet-1586	83	14	:	:	PUNCT
admet-1586	83	15	0.2	0.2	NUM
admet-1586	83	16	mm	mm	NOUN
admet-1586	83	17	)	)	PUNCT
admet-1586	83	18	of	of	ADP
admet-1586	83	19	an	an	DET
admet-1586	83	20	aluminum	aluminum	NOUN
admet-1586	83	21	plate	plate	NOUN
admet-1586	83	22	were	be	AUX
admet-1586	83	23	placed	place	VERB
admet-1586	83	24	into	into	ADP
admet-1586	83	25	a	a	DET
admet-1586	83	26	desiccator	desiccator	NOUN
admet-1586	83	27	with	with	ADP
admet-1586	83	28	silica	silica	NOUN
admet-1586	83	29	gel	gel	NOUN
admet-1586	83	30	.	.	PUNCT
admet-1586	84	1	the	the	DET
admet-1586	84	2	samples	sample	NOUN
admet-1586	84	3	in	in	ADP
admet-1586	84	4	the	the	DET
admet-1586	84	5	desiccator	desiccator	NOUN
admet-1586	84	6	were	be	AUX
admet-1586	84	7	stored	store	VERB
admet-1586	84	8	at	at	ADP
admet-1586	84	9	40	40	NUM
admet-1586	84	10	°	°	ADP
admet-1586	84	11	c	c	NOUN
admet-1586	84	12	for	for	ADP
admet-1586	84	13	three	three	NUM
admet-1586	84	14	months	month	NOUN
admet-1586	84	15	,	,	PUNCT
admet-1586	84	16	followed	follow	VERB
admet-1586	84	17	by	by	ADP
admet-1586	84	18	xrpd	xrpd	PROPN
admet-1586	84	19	measurement	measurement	PROPN
admet-1586	84	20	.	.	PUNCT
admet-1586	85	1	dissolution	dissolution	NOUN
admet-1586	85	2	-	-	PUNCT
admet-1586	85	3	permeation	permeation	NOUN
admet-1586	85	4	test	test	NOUN
admet-1586	85	5	dissolution	dissolution	NOUN
admet-1586	85	6	and	and	CCONJ
admet-1586	85	7	permeation	permeation	NOUN
admet-1586	85	8	of	of	ADP
admet-1586	85	9	the	the	DET
admet-1586	85	10	crystalline	crystalline	NOUN
admet-1586	85	11	imc	imc	NOUN
admet-1586	85	12	and	and	CCONJ
admet-1586	85	13	the	the	DET
admet-1586	85	14	solid	solid	ADJ
admet-1586	85	15	dispersion	dispersion	NOUN
admet-1586	85	16	samples	sample	NOUN
admet-1586	85	17	were	be	AUX
admet-1586	85	18	simultaneously	simultaneously	ADV
admet-1586	85	19	measured	measure	VERB
admet-1586	85	20	using	use	VERB
admet-1586	85	21	microflux	microflux	PROPN
admet-1586	85	22	™	™	PROPN
admet-1586	85	23	(	(	PUNCT
admet-1586	85	24	pion	pion	PROPN
admet-1586	85	25	inc	inc	PROPN
admet-1586	85	26	.	.	PROPN
admet-1586	85	27	,	,	PUNCT
admet-1586	85	28	ma	ma	PROPN
admet-1586	85	29	,	,	PUNCT
admet-1586	85	30	usa	usa	PROPN
admet-1586	85	31	)	)	PUNCT
admet-1586	85	32	.	.	PUNCT
admet-1586	86	1	the	the	DET
admet-1586	86	2	apparatus	apparatus	NOUN
admet-1586	86	3	contains	contain	VERB
admet-1586	86	4	donor	donor	NOUN
admet-1586	86	5	and	and	CCONJ
admet-1586	86	6	acceptor	acceptor	NOUN
admet-1586	86	7	chambers	chamber	NOUN
admet-1586	86	8	connected	connect	VERB
admet-1586	86	9	through	through	ADP
admet-1586	86	10	an	an	DET
admet-1586	86	11	artificial	artificial	ADJ
admet-1586	86	12	membrane	membrane	NOUN
admet-1586	86	13	(	(	PUNCT
admet-1586	86	14	ϕ	ϕ	NOUN
admet-1586	86	15	0.45	0.45	NUM
admet-1586	86	16	μm	μm	NOUN
admet-1586	86	17	of	of	ADP
admet-1586	86	18	polyvinylidenfluoride	polyvinylidenfluoride	ADJ
admet-1586	86	19	)	)	PUNCT
admet-1586	86	20	.	.	PUNCT
admet-1586	87	1	the	the	DET
admet-1586	87	2	measurement	measurement	NOUN
admet-1586	87	3	conditions	condition	NOUN
admet-1586	87	4	were	be	AUX
admet-1586	87	5	set	set	VERB
admet-1586	87	6	by	by	ADP
admet-1586	87	7	modifying	modify	VERB
admet-1586	87	8	those	those	PRON
admet-1586	87	9	of	of	ADP
admet-1586	87	10	previous	previous	ADJ
admet-1586	87	11	studies	study	NOUN
admet-1586	87	12	[	[	X
admet-1586	87	13	20	20	NUM
admet-1586	87	14	]	]	PUNCT
admet-1586	87	15	.	.	PUNCT
admet-1586	88	1	first	first	ADV
admet-1586	88	2	,	,	PUNCT
admet-1586	88	3	25	25	NUM
admet-1586	88	4	μl	μl	ADP
admet-1586	88	5	of	of	ADP
admet-1586	88	6	git-0	git-0	X
admet-1586	88	7	lipid	lipid	ADJ
admet-1586	88	8	solution	solution	NOUN
admet-1586	88	9	was	be	AUX
admet-1586	88	10	dripped	drip	VERB
admet-1586	88	11	onto	onto	ADP
admet-1586	88	12	the	the	DET
admet-1586	88	13	membrane	membrane	NOUN
admet-1586	88	14	surface	surface	NOUN
admet-1586	88	15	from	from	ADP
admet-1586	88	16	the	the	DET
admet-1586	88	17	donor	donor	NOUN
admet-1586	88	18	side	side	NOUN
admet-1586	88	19	.	.	PUNCT
admet-1586	89	1	thereafter	thereafter	ADV
admet-1586	89	2	,	,	PUNCT
admet-1586	89	3	20	20	NUM
admet-1586	89	4	ml	ml	NOUN
admet-1586	89	5	of	of	ADP
admet-1586	89	6	prisma	prisma	PROPN
admet-1586	89	7	ht	ht	PROPN
admet-1586	89	8	buffer	buffer	VERB
admet-1586	89	9	and	and	CCONJ
admet-1586	89	10	acceptor	acceptor	NOUN
admet-1586	89	11	sink	sink	NOUN
admet-1586	89	12	buffer	buffer	NOUN
admet-1586	89	13	(	(	PUNCT
admet-1586	89	14	asb)were	asb)were	ADV
admet-1586	89	15	added	add	VERB
admet-1586	89	16	to	to	ADP
admet-1586	89	17	the	the	DET
admet-1586	89	18	donor	donor	NOUN
admet-1586	89	19	and	and	CCONJ
admet-1586	89	20	acceptor	acceptor	NOUN
admet-1586	89	21	chambers	chamber	NOUN
admet-1586	89	22	.	.	PUNCT
admet-1586	90	1	prisma	prisma	PROPN
admet-1586	90	2	ht	ht	PROPN
admet-1586	90	3	,	,	PUNCT
admet-1586	90	4	a	a	DET
admet-1586	90	5	ph	ph	ADJ
admet-1586	90	6	6.5	6.5	NUM
admet-1586	90	7	buffer	buffer	NOUN
admet-1586	90	8	,	,	PUNCT
admet-1586	90	9	acts	act	VERB
admet-1586	90	10	as	as	ADP
admet-1586	90	11	the	the	DET
admet-1586	90	12	donor	donor	NOUN
admet-1586	90	13	medium	medium	NOUN
admet-1586	90	14	and	and	CCONJ
admet-1586	90	15	does	do	AUX
admet-1586	90	16	not	not	PART
admet-1586	90	17	contain	contain	VERB
admet-1586	90	18	phosphate	phosphate	ADJ
admet-1586	90	19	,	,	PUNCT
admet-1586	90	20	boric	boric	ADJ
admet-1586	90	21	acid	acid	NOUN
admet-1586	90	22	,	,	PUNCT
admet-1586	90	23	citric	citric	ADJ
admet-1586	90	24	acid	acid	NOUN
admet-1586	90	25	,	,	PUNCT
admet-1586	90	26	or	or	CCONJ
admet-1586	90	27	benzoate	benzoate	NOUN
admet-1586	90	28	.	.	PUNCT
admet-1586	91	1	asb	asb	PROPN
admet-1586	91	2	is	be	AUX
admet-1586	91	3	a	a	DET
admet-1586	91	4	hepes	hepe	NOUN
admet-1586	91	5	-	-	PUNCT
admet-1586	91	6	based	base	VERB
admet-1586	91	7	,	,	PUNCT
admet-1586	91	8	ph	ph	ADJ
admet-1586	91	9	7.4	7.4	NUM
admet-1586	91	10	buffer	buffer	NOUN
admet-1586	91	11	,	,	PUNCT
admet-1586	91	12	and	and	CCONJ
admet-1586	91	13	acts	act	VERB
admet-1586	91	14	as	as	ADP
admet-1586	91	15	the	the	DET
admet-1586	91	16	acceptor	acceptor	NOUN
admet-1586	91	17	buffer	buffer	NOUN
admet-1586	91	18	,	,	PUNCT
admet-1586	91	19	which	which	PRON
admet-1586	91	20	contains	contain	VERB
admet-1586	91	21	chemical	chemical	ADJ
admet-1586	91	22	scavengers	scavenger	NOUN
admet-1586	91	23	to	to	PART
admet-1586	91	24	maintain	maintain	VERB
admet-1586	91	25	sink	sink	NOUN
admet-1586	91	26	conditions	condition	NOUN
admet-1586	91	27	[	[	X
admet-1586	91	28	21,22	21,22	X
admet-1586	91	29	]	]	X
admet-1586	91	30	.	.	PUNCT
admet-1586	92	1	the	the	DET
admet-1586	92	2	solid	solid	ADJ
admet-1586	92	3	dispersion	dispersion	NOUN
admet-1586	92	4	samples	sample	NOUN
admet-1586	92	5	corresponding	correspond	VERB
admet-1586	92	6	to	to	ADP
admet-1586	92	7	10	10	NUM
admet-1586	92	8	mg	mg	PROPN
admet-1586	92	9	of	of	ADP
admet-1586	92	10	imc	imc	PROPN
admet-1586	92	11	were	be	AUX
admet-1586	92	12	added	add	VERB
admet-1586	92	13	to	to	ADP
admet-1586	92	14	the	the	DET
admet-1586	92	15	donor	donor	NOUN
admet-1586	92	16	chamber	chamber	PROPN
admet-1586	92	17	.	.	PUNCT
admet-1586	93	1	the	the	DET
admet-1586	93	2	dissolution	dissolution	NOUN
admet-1586	93	3	media	medium	NOUN
admet-1586	93	4	in	in	ADP
admet-1586	93	5	both	both	DET
admet-1586	93	6	chambers	chamber	NOUN
admet-1586	93	7	were	be	AUX
admet-1586	93	8	stirred	stir	VERB
admet-1586	93	9	at	at	ADP
admet-1586	93	10	150	150	NUM
admet-1586	93	11	rpm	rpm	NOUN
admet-1586	93	12	at	at	ADP
admet-1586	93	13	37	37	NUM
admet-1586	93	14	°	°	NOUN
admet-1586	93	15	c	c	NOUN
admet-1586	93	16	.	.	PUNCT
admet-1586	94	1	the	the	DET
admet-1586	94	2	uv	uv	NOUN
admet-1586	94	3	probes	probe	NOUN
admet-1586	94	4	of	of	ADP
admet-1586	94	5	2	2	NUM
admet-1586	94	6	and	and	CCONJ
admet-1586	94	7	5	5	NUM
admet-1586	94	8	mm	mm	NOUN
admet-1586	94	9	were	be	AUX
admet-1586	94	10	inserted	insert	VERB
admet-1586	94	11	into	into	ADP
admet-1586	94	12	the	the	DET
admet-1586	94	13	donor	donor	NOUN
admet-1586	94	14	,	,	PUNCT
admet-1586	94	15	and	and	CCONJ
admet-1586	94	16	acceptor	acceptor	NOUN
admet-1586	94	17	chambers	chamber	NOUN
admet-1586	94	18	,	,	PUNCT
admet-1586	94	19	respectively	respectively	ADV
admet-1586	94	20	,	,	PUNCT
admet-1586	94	21	and	and	CCONJ
admet-1586	94	22	the	the	DET
admet-1586	94	23	concentration	concentration	NOUN
admet-1586	94	24	of	of	ADP
admet-1586	94	25	imc	imc	PROPN
admet-1586	94	26	was	be	AUX
admet-1586	94	27	measured	measure	VERB
admet-1586	94	28	using	use	VERB
admet-1586	94	29	a	a	DET
admet-1586	94	30	uv	uv	NOUN
admet-1586	94	31	spectrometer	spectrometer	NOUN
admet-1586	94	32	at	at	ADP
admet-1586	94	33	370	370	NUM
admet-1586	94	34	nm	nm	NOUN
admet-1586	94	35	every	every	DET
admet-1586	94	36	5	5	NUM
admet-1586	94	37	s	s	X
admet-1586	94	38	(	(	PUNCT
admet-1586	94	39	0	0	NUM
admet-1586	94	40	10	10	NUM
admet-1586	94	41	min	min	NOUN
admet-1586	94	42	)	)	PUNCT
admet-1586	94	43	,	,	PUNCT
admet-1586	94	44	20	20	NUM
admet-1586	94	45	s	s	NOUN
admet-1586	94	46	(	(	PUNCT
admet-1586	94	47	10.5	10.5	NUM
admet-1586	94	48	60	60	NUM
admet-1586	94	49	min	min	NOUN
admet-1586	94	50	)	)	PUNCT
admet-1586	94	51	,	,	PUNCT
admet-1586	94	52	1	1	NUM
admet-1586	94	53	min	min	NOUN
admet-1586	94	54	(	(	PUNCT
admet-1586	94	55	61	61	NUM
admet-1586	94	56	120	120	NUM
admet-1586	94	57	min	min	NOUN
admet-1586	94	58	)	)	PUNCT
admet-1586	94	59	,	,	PUNCT
admet-1586	94	60	and	and	CCONJ
admet-1586	94	61	2	2	NUM
admet-1586	94	62	min	min	NOUN
admet-1586	94	63	(	(	PUNCT
admet-1586	94	64	121	121	NUM
admet-1586	94	65	–	–	SYM
admet-1586	94	66	480	480	NUM
admet-1586	94	67	min	min	NOUN
admet-1586	94	68	)	)	PUNCT
admet-1586	94	69	.	.	PUNCT
admet-1586	95	1	the	the	DET
admet-1586	95	2	concentration	concentration	NOUN
admet-1586	95	3	of	of	ADP
admet-1586	95	4	imc	imc	PROPN
admet-1586	95	5	was	be	AUX
admet-1586	95	6	corrected	correct	VERB
admet-1586	95	7	with	with	ADP
admet-1586	95	8	a	a	DET
admet-1586	95	9	change	change	NOUN
admet-1586	95	10	in	in	ADP
admet-1586	95	11	baseline	baseline	ADJ
admet-1586	95	12	values	value	NOUN
admet-1586	95	13	using	use	VERB
admet-1586	95	14	the	the	DET
admet-1586	95	15	difference	difference	NOUN
admet-1586	95	16	between	between	ADP
admet-1586	95	17	370	370	NUM
admet-1586	95	18	and	and	CCONJ
admet-1586	95	19	380	380	NUM
admet-1586	95	20	nm	nm	NOUN
admet-1586	95	21	.	.	PUNCT
admet-1586	96	1	a	a	DET
admet-1586	96	2	standard	standard	ADJ
admet-1586	96	3	curve	curve	NOUN
admet-1586	96	4	for	for	ADP
admet-1586	96	5	imc	imc	PROPN
admet-1586	96	6	between	between	ADP
admet-1586	96	7	20.0	20.0	NUM
admet-1586	96	8	-	-	SYM
admet-1586	96	9	558.1	558.1	NUM
admet-1586	96	10	μg	μg	PROPN
admet-1586	96	11	ml-1	ml-1	ADV
admet-1586	96	12	in	in	ADP
admet-1586	96	13	both	both	DET
admet-1586	96	14	chambers	chamber	NOUN
admet-1586	96	15	was	be	AUX
admet-1586	96	16	plotted	plot	VERB
admet-1586	96	17	.	.	PUNCT
admet-1586	97	1	the	the	DET
admet-1586	97	2	flux	flux	NOUN
admet-1586	97	3	values	value	VERB
admet-1586	97	4	through	through	ADP
admet-1586	97	5	the	the	DET
admet-1586	97	6	membrane	membrane	NOUN
admet-1586	97	7	were	be	AUX
admet-1586	97	8	obtained	obtain	VERB
admet-1586	97	9	for	for	ADP
admet-1586	97	10	crystalline	crystalline	NOUN
admet-1586	97	11	imc	imc	PROPN
admet-1586	97	12	and	and	CCONJ
admet-1586	97	13	the	the	DET
admet-1586	97	14	solid	solid	ADJ
admet-1586	97	15	dispersions	dispersion	NOUN
admet-1586	97	16	of	of	ADP
admet-1586	97	17	imc	imc	PROPN
admet-1586	97	18	-	-	PUNCT
admet-1586	97	19	mg	mg	PROPN
admet-1586	97	20	(	(	PUNCT
admet-1586	97	21	20	20	NUM
admet-1586	97	22	:	:	SYM
admet-1586	97	23	80	80	NUM
admet-1586	97	24	)	)	PUNCT
admet-1586	97	25	and	and	CCONJ
admet-1586	97	26	imc	imc	PROPN
admet-1586	97	27	-	-	PUNCT
admet-1586	97	28	mx	mx	PROPN
admet-1586	97	29	(	(	PUNCT
admet-1586	97	30	20:80	20:80	NUM
admet-1586	97	31	)	)	PUNCT
admet-1586	97	32	in	in	ADP
admet-1586	97	33	accordance	accordance	NOUN
admet-1586	97	34	with	with	ADP
admet-1586	97	35	the	the	DET
admet-1586	97	36	methods	method	NOUN
admet-1586	97	37	previously	previously	ADV
admet-1586	97	38	described	describe	VERB
admet-1586	97	39	in	in	ADP
admet-1586	97	40	the	the	DET
admet-1586	97	41	literature	literature	NOUN
admet-1586	98	1	[	[	X
admet-1586	98	2	23,24	23,24	X
admet-1586	98	3	]	]	PUNCT
admet-1586	98	4	.	.	PUNCT
admet-1586	99	1	the	the	DET
admet-1586	99	2	flux	flux	NOUN
admet-1586	99	3	value	value	NOUN
admet-1586	99	4	was	be	AUX
admet-1586	99	5	calculated	calculate	VERB
admet-1586	99	6	as	as	SCONJ
admet-1586	99	7	follows	follow	VERB
admet-1586	99	8	:	:	PUNCT
admet-1586	99	9	flux	flux	NOUN
admet-1586	99	10	value	value	NOUN
admet-1586	99	11	,	,	PUNCT
admet-1586	99	12	(	(	PUNCT
admet-1586	99	13	µg	µg	NOUN
admet-1586	99	14	min-1	min-1	NOUN
admet-1586	99	15	)	)	PUNCT
admet-1586	99	16	cm-2	cm-2	NOUN
admet-1586	100	1	=	=	PUNCT
admet-1586	100	2	the	the	DET
admet-1586	100	3	permeated	permeate	VERB
admet-1586	100	4	slope	slope	NOUN
admet-1586	100	5	,	,	PUNCT
admet-1586	100	6	µg	µg	ADV
admet-1586	100	7	ml-1	ml-1	X
admet-1586	100	8	)	)	PUNCT
admet-1586	100	9	min-1	min-1	X
admet-1586	100	10			VERB
admet-1586	100	11	the	the	DET
admet-1586	100	12	volume	volume	NOUN
admet-1586	100	13	of	of	ADP
admet-1586	100	14	the	the	DET
admet-1586	100	15	acceptor	acceptor	NOUN
admet-1586	100	16	chamber	chamber	PROPN
admet-1586	100	17	/the	/the	DET
admet-1586	100	18	surface	surface	NOUN
admet-1586	100	19	area	area	NOUN
admet-1586	100	20	of	of	ADP
admet-1586	100	21	the	the	DET
admet-1586	100	22	membrane	membrane	NOUN
admet-1586	100	23	.	.	PUNCT
admet-1586	101	1	solubility	solubility	NOUN
admet-1586	101	2	test	test	VERB
admet-1586	101	3	the	the	DET
admet-1586	101	4	solubility	solubility	NOUN
admet-1586	101	5	of	of	ADP
admet-1586	101	6	crystalline	crystalline	PROPN
admet-1586	101	7	imc	imc	PROPN
admet-1586	101	8	in	in	ADP
admet-1586	101	9	the	the	DET
admet-1586	101	10	media	medium	NOUN
admet-1586	101	11	used	use	VERB
admet-1586	101	12	in	in	ADP
admet-1586	101	13	both	both	CCONJ
admet-1586	101	14	donor	donor	NOUN
admet-1586	101	15	and	and	CCONJ
admet-1586	101	16	acceptor	acceptor	NOUN
admet-1586	101	17	chambers	chamber	NOUN
admet-1586	101	18	of	of	ADP
admet-1586	101	19	the	the	DET
admet-1586	101	20	microflux	microflux	NOUN
admet-1586	101	21	™	™	ADJ
admet-1586	101	22	apparatus	apparatus	NOUN
admet-1586	101	23	was	be	AUX
admet-1586	101	24	measured	measure	VERB
admet-1586	101	25	.	.	PUNCT
admet-1586	102	1	approximately	approximately	ADV
admet-1586	102	2	50	50	NUM
admet-1586	102	3	mg	mg	NOUN
admet-1586	102	4	of	of	ADP
admet-1586	102	5	crystalline	crystalline	PROPN
admet-1586	102	6	imc	imc	PROPN
admet-1586	102	7	was	be	AUX
admet-1586	102	8	added	add	VERB
admet-1586	102	9	to	to	ADP
admet-1586	102	10	5	5	NUM
admet-1586	102	11	ml	ml	NOUN
admet-1586	102	12	of	of	ADP
admet-1586	102	13	prisma	prisma	PROPN
admet-1586	102	14	ht	ht	PROPN
admet-1586	102	15	(	(	PUNCT
admet-1586	102	16	ph	ph	PROPN
admet-1586	102	17	6.5	6.5	NUM
admet-1586	102	18	)	)	PUNCT
admet-1586	102	19	and	and	CCONJ
admet-1586	102	20	asb	asb	PROPN
admet-1586	102	21	(	(	PUNCT
admet-1586	102	22	ph	ph	VERB
admet-1586	102	23	7.4	7.4	NUM
admet-1586	102	24	)	)	PUNCT
admet-1586	102	25	buffers	buffer	NOUN
admet-1586	102	26	.	.	PUNCT
admet-1586	103	1	they	they	PRON
admet-1586	103	2	were	be	AUX
admet-1586	103	3	shaken	shake	VERB
admet-1586	103	4	at	at	ADP
admet-1586	103	5	70	70	NUM
admet-1586	103	6	cycles	cycle	NOUN
admet-1586	103	7	/	/	SYM
admet-1586	103	8	min	min	NOUN
admet-1586	103	9	in	in	ADP
admet-1586	103	10	an	an	DET
admet-1586	103	11	mm-10	mm-10	X
admet-1586	103	12	water	water	NOUN
admet-1586	103	13	bath	bath	NOUN
admet-1586	103	14	shaker	shaker	NOUN
admet-1586	103	15	(	(	PUNCT
admet-1586	103	16	taitec	taitec	NOUN
admet-1586	103	17	,	,	PUNCT
admet-1586	103	18	koshigaya	koshigaya	PROPN
admet-1586	103	19	,	,	PUNCT
admet-1586	103	20	saitama	saitama	PROPN
admet-1586	103	21	,	,	PUNCT
admet-1586	103	22	japan	japan	PROPN
admet-1586	103	23	)	)	PUNCT
admet-1586	103	24	at	at	ADP
admet-1586	103	25	37	37	NUM
admet-1586	103	26	°	°	NOUN
admet-1586	103	27	c	c	NOUN
admet-1586	103	28	for	for	ADP
admet-1586	103	29	24	24	NUM
admet-1586	103	30	h.	h.	PROPN
admet-1586	103	31	the	the	DET
admet-1586	103	32	test	test	NOUN
admet-1586	103	33	media	medium	NOUN
admet-1586	103	34	were	be	AUX
admet-1586	103	35	filtered	filter	VERB
admet-1586	103	36	through	through	ADP
admet-1586	103	37	a	a	DET
admet-1586	103	38	0.45	0.45	NUM
admet-1586	103	39	-	-	PUNCT
admet-1586	103	40	mm	mm	NOUN
admet-1586	103	41	syringe	syringe	NOUN
admet-1586	103	42	filter	filter	NOUN
admet-1586	103	43	(	(	PUNCT
admet-1586	103	44	gl	gl	PROPN
admet-1586	103	45	sciences	sciences	PROPN
admet-1586	103	46	inc	inc	PROPN
admet-1586	103	47	.	.	PROPN
admet-1586	103	48	,	,	PUNCT
admet-1586	103	49	tokyo	tokyo	PROPN
admet-1586	103	50	,	,	PUNCT
admet-1586	103	51	japan	japan	PROPN
admet-1586	103	52	)	)	PUNCT
admet-1586	103	53	.	.	PUNCT
admet-1586	104	1	approximately	approximately	ADV
admet-1586	104	2	1	1	NUM
admet-1586	104	3	ml	ml	NOUN
admet-1586	104	4	of	of	ADP
admet-1586	104	5	the	the	DET
admet-1586	104	6	filtrate	filtrate	NOUN
admet-1586	104	7	was	be	AUX
admet-1586	104	8	analyzed	analyze	VERB
admet-1586	104	9	using	use	VERB
admet-1586	104	10	a	a	DET
admet-1586	104	11	waters	water	NOUN
admet-1586	104	12	acquity	acquity	NOUN
admet-1586	104	13	uplc	uplc	VERB
admet-1586	104	14	h	h	ADJ
admet-1586	104	15	-	-	PUNCT
admet-1586	104	16	class	class	NOUN
admet-1586	104	17	system	system	NOUN
admet-1586	104	18	(	(	PUNCT
admet-1586	104	19	waters	water	NOUN
admet-1586	104	20	corporation	corporation	NOUN
admet-1586	104	21	,	,	PUNCT
admet-1586	104	22	massachusetts	massachusetts	PROPN
admet-1586	104	23	,	,	PUNCT
admet-1586	104	24	usa	usa	PROPN
admet-1586	104	25	)	)	PUNCT
admet-1586	104	26	.	.	PUNCT
admet-1586	105	1	the	the	DET
admet-1586	105	2	measurement	measurement	NOUN
admet-1586	105	3	conditions	condition	NOUN
admet-1586	105	4	were	be	AUX
admet-1586	105	5	as	as	SCONJ
admet-1586	105	6	follows	follow	VERB
admet-1586	105	7	:	:	PUNCT
admet-1586	105	8	mobile	mobile	ADJ
admet-1586	105	9	phase	phase	NOUN
admet-1586	105	10	,	,	PUNCT
admet-1586	105	11	0.1	0.1	NUM
admet-1586	105	12	%	%	NOUN
admet-1586	105	13	trifluoroacetic	trifluoroacetic	ADJ
admet-1586	105	14	acid	acid	NOUN
admet-1586	105	15	/	/	SYM
admet-1586	105	16	acetonitrile	acetonitrile	NOUN
admet-1586	105	17	;	;	PUNCT
admet-1586	105	18	flow	flow	NOUN
admet-1586	105	19	rate	rate	NOUN
admet-1586	105	20	0.4	0.4	NUM
admet-1586	105	21	ml	ml	NOUN
admet-1586	105	22	min-1	min-1	NOUN
admet-1586	105	23	;	;	PUNCT
admet-1586	105	24	injection	injection	NOUN
admet-1586	105	25	volume	volume	NOUN
admet-1586	105	26	2	2	NUM
admet-1586	105	27	µl	µl	NOUN
admet-1586	105	28	;	;	PUNCT
admet-1586	105	29	uv	uv	NOUN
admet-1586	105	30	absorbance	absorbance	NOUN
admet-1586	105	31	270	270	NUM
admet-1586	105	32	nm	nm	NOUN
admet-1586	105	33	,	,	PUNCT
admet-1586	105	34	and	and	CCONJ
admet-1586	105	35	column	column	NOUN
admet-1586	105	36	acquity	acquity	NOUN
admet-1586	105	37	uplc	uplc	PROPN
admet-1586	105	38	beh	beh	PROPN
admet-1586	105	39	c18	c18	PROPN
admet-1586	105	40	2.1	2.1	NUM
admet-1586	105	41	×	×	NOUN
admet-1586	105	42	100	100	NUM
admet-1586	105	43	mm	mm	NOUN
admet-1586	105	44	,	,	PUNCT
admet-1586	105	45	1.7μm	1.7μm	PROPN
admet-1586	105	46	at	at	ADP
admet-1586	105	47	35	35	NUM
admet-1586	105	48	°	°	NOUN
admet-1586	105	49	c	c	NOUN
admet-1586	105	50	.	.	PUNCT
admet-1586	106	1	measurement	measurement	NOUN
admet-1586	106	2	of	of	ADP
admet-1586	106	3	the	the	DET
admet-1586	106	4	drug	drug	NOUN
admet-1586	106	5	-	-	PUNCT
admet-1586	106	6	rich	rich	ADJ
admet-1586	106	7	colloid	colloid	NOUN
admet-1586	106	8	prior	prior	ADV
admet-1586	106	9	to	to	ADP
admet-1586	106	10	the	the	DET
admet-1586	106	11	experiment	experiment	NOUN
admet-1586	106	12	,	,	PUNCT
admet-1586	106	13	the	the	DET
admet-1586	106	14	prisma	prisma	NOUN
admet-1586	106	15	ht	ht	PROPN
admet-1586	106	16	buffer	buffer	NOUN
admet-1586	106	17	was	be	AUX
admet-1586	106	18	filtered	filter	VERB
admet-1586	106	19	through	through	ADP
admet-1586	106	20	a	a	DET
admet-1586	106	21	0.45	0.45	NUM
admet-1586	106	22	-	-	PUNCT
admet-1586	106	23	mm	mm	NOUN
admet-1586	106	24	syringe	syringe	NOUN
admet-1586	106	25	filter	filter	NOUN
admet-1586	106	26	(	(	PUNCT
admet-1586	106	27	gl	gl	PROPN
admet-1586	106	28	sciences	sciences	PROPN
admet-1586	106	29	inc	inc	PROPN
admet-1586	106	30	.	.	PROPN
admet-1586	106	31	,	,	PUNCT
admet-1586	106	32	tokyo	tokyo	PROPN
admet-1586	106	33	,	,	PUNCT
admet-1586	106	34	japan	japan	PROPN
admet-1586	106	35	)	)	PUNCT
admet-1586	106	36	.	.	PUNCT
admet-1586	107	1	a	a	DET
admet-1586	107	2	sample	sample	NOUN
admet-1586	107	3	of	of	ADP
admet-1586	107	4	the	the	DET
admet-1586	107	5	solid	solid	ADJ
admet-1586	107	6	dispersions	dispersion	NOUN
admet-1586	107	7	(	(	PUNCT
admet-1586	107	8	5	5	NUM
admet-1586	107	9	mg	mg	NOUN
admet-1586	107	10	)	)	PUNCT
admet-1586	107	11	corresponding	correspond	VERB
admet-1586	107	12	to	to	ADP
admet-1586	107	13	1	1	NUM
admet-1586	107	14	mg	mg	PROPN
admet-1586	107	15	of	of	ADP
admet-1586	107	16	imc	imc	PROPN
admet-1586	107	17	was	be	AUX
admet-1586	107	18	added	add	VERB
admet-1586	107	19	to	to	ADP
admet-1586	107	20	2	2	NUM
admet-1586	107	21	ml	ml	NOUN
admet-1586	107	22	of	of	ADP
admet-1586	107	23	the	the	DET
admet-1586	107	24	filtered	filter	VERB
admet-1586	107	25	prisma	prisma	NOUN
admet-1586	107	26	ht	ht	PROPN
admet-1586	107	27	buffer	buffer	NOUN
admet-1586	107	28	.	.	PUNCT
admet-1586	108	1	they	they	PRON
admet-1586	108	2	were	be	AUX
admet-1586	108	3	shaken	shake	VERB
admet-1586	108	4	at	at	ADP
admet-1586	108	5	500	500	NUM
admet-1586	108	6	rpm	rpm	NOUN
admet-1586	108	7	at	at	ADP
admet-1586	108	8	37	37	NUM
admet-1586	108	9	°	°	NOUN
admet-1586	108	10	c	c	NOUN
admet-1586	108	11	for	for	ADP
admet-1586	108	12	4	4	NUM
admet-1586	108	13	h	h	NOUN
admet-1586	108	14	using	use	VERB
admet-1586	108	15	a	a	DET
admet-1586	108	16	well	well	ADJ
admet-1586	108	17	plate	plate	NOUN
admet-1586	108	18	shaker	shaker	NOUN
admet-1586	108	19	,	,	PUNCT
admet-1586	108	20	m	m	PROPN
admet-1586	108	21	admet	admet	PROPN
admet-1586	108	22	&	&	CCONJ
admet-1586	108	23	dmpk	dmpk	PROPN
admet-1586	108	24	11(3	11(3	NUM
admet-1586	108	25	)	)	PUNCT
admet-1586	108	26	(	(	PUNCT
admet-1586	108	27	2023	2023	NUM
admet-1586	108	28	)	)	PUNCT
admet-1586	108	29	373	373	NUM
admet-1586	108	30	-	-	SYM
admet-1586	108	31	385	385	NUM
admet-1586	108	32	dissolution	dissolution	NOUN
admet-1586	108	33	-	-	PUNCT
admet-1586	108	34	permeation	permeation	NOUN
admet-1586	108	35	of	of	ADP
admet-1586	108	36	hot	hot	ADJ
admet-1586	108	37	-	-	PUNCT
admet-1586	108	38	melt	melt	NOUN
admet-1586	108	39	extruded	extrude	VERB
admet-1586	108	40	asd	asd	NOUN
admet-1586	108	41	doi	doi	PROPN
admet-1586	108	42	:	:	PUNCT
admet-1586	108	43	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	NOUN
admet-1586	108	44	377	377	NUM
admet-1586	108	45	br-022up	br-022up	NUM
admet-1586	108	46	(	(	PUNCT
admet-1586	108	47	taitec	taitec	NOUN
admet-1586	108	48	corporation	corporation	NOUN
admet-1586	108	49	,	,	PUNCT
admet-1586	108	50	saitama	saitama	PROPN
admet-1586	108	51	,	,	PUNCT
admet-1586	108	52	japan	japan	PROPN
admet-1586	108	53	)	)	PUNCT
admet-1586	108	54	,	,	PUNCT
admet-1586	108	55	followed	follow	VERB
admet-1586	108	56	by	by	ADP
admet-1586	108	57	filtration	filtration	NOUN
admet-1586	108	58	through	through	ADP
admet-1586	108	59	a	a	DET
admet-1586	108	60	0.45	0.45	NUM
admet-1586	108	61	-	-	PUNCT
admet-1586	108	62	μm	μm	NOUN
admet-1586	108	63	syringe	syringe	NOUN
admet-1586	108	64	filter	filter	NOUN
admet-1586	108	65	(	(	PUNCT
admet-1586	108	66	gl	gl	PROPN
admet-1586	108	67	sciences	sciences	PROPN
admet-1586	108	68	inc	inc	PROPN
admet-1586	108	69	.	.	PROPN
admet-1586	108	70	,	,	PUNCT
admet-1586	108	71	tokyo	tokyo	PROPN
admet-1586	108	72	,	,	PUNCT
admet-1586	108	73	japan	japan	PROPN
admet-1586	108	74	)	)	PUNCT
admet-1586	108	75	.	.	PUNCT
admet-1586	109	1	approximately	approximately	ADV
admet-1586	109	2	100	100	NUM
admet-1586	109	3	μl	μl	ADP
admet-1586	109	4	of	of	ADP
admet-1586	109	5	the	the	DET
admet-1586	109	6	filtrate	filtrate	ADJ
admet-1586	109	7	sample	sample	NOUN
admet-1586	109	8	was	be	AUX
admet-1586	109	9	added	add	VERB
admet-1586	109	10	to	to	ADP
admet-1586	109	11	a	a	DET
admet-1586	109	12	cuvette	cuvette	NOUN
admet-1586	109	13	to	to	PART
admet-1586	109	14	measure	measure	VERB
admet-1586	109	15	dynamic	dynamic	ADJ
admet-1586	109	16	light	light	NOUN
admet-1586	109	17	scattering	scattering	NOUN
admet-1586	109	18	(	(	PUNCT
admet-1586	109	19	dls	dls	PROPN
admet-1586	109	20	)	)	PUNCT
admet-1586	109	21	using	use	VERB
admet-1586	109	22	zetasizer	zetasizer	NOUN
admet-1586	109	23	nano	nano	NOUN
admet-1586	109	24	-	-	SYM
admet-1586	109	25	zs	zs	PROPN
admet-1586	109	26	(	(	PUNCT
admet-1586	109	27	malvern	malvern	PROPN
admet-1586	109	28	panalytical	panalytical	PROPN
admet-1586	109	29	ltd	ltd	PROPN
admet-1586	109	30	.	.	PROPN
admet-1586	109	31	,	,	PUNCT
admet-1586	109	32	malvern	malvern	PROPN
admet-1586	109	33	,	,	PUNCT
admet-1586	109	34	uk	uk	PROPN
admet-1586	109	35	)	)	PUNCT
admet-1586	109	36	.	.	PUNCT
admet-1586	110	1	the	the	DET
admet-1586	110	2	mean	mean	ADJ
admet-1586	110	3	diameter	diameter	NOUN
admet-1586	110	4	was	be	AUX
admet-1586	110	5	calculated	calculate	VERB
admet-1586	110	6	using	use	VERB
admet-1586	110	7	photon	photon	NOUN
admet-1586	110	8	correlation	correlation	NOUN
admet-1586	110	9	spectroscopy	spectroscopy	NOUN
admet-1586	110	10	,	,	PUNCT
admet-1586	110	11	and	and	CCONJ
admet-1586	110	12	the	the	DET
admet-1586	110	13	attenuation	attenuation	NOUN
admet-1586	110	14	and	and	CCONJ
admet-1586	110	15	measurement	measurement	NOUN
admet-1586	110	16	settings	setting	NOUN
admet-1586	110	17	were	be	AUX
admet-1586	110	18	optimized	optimize	VERB
admet-1586	110	19	automatically	automatically	ADV
admet-1586	110	20	by	by	ADP
admet-1586	110	21	zetasizer	zetasizer	PROPN
admet-1586	110	22	software	software	PROPN
admet-1586	110	23	version	version	PROPN
admet-1586	110	24	8.01	8.01	NUM
admet-1586	110	25	(	(	PUNCT
admet-1586	110	26	malvern	malvern	PROPN
admet-1586	110	27	panalytical	panalytical	PROPN
admet-1586	110	28	ltd	ltd	PROPN
admet-1586	110	29	.	.	PROPN
admet-1586	110	30	,	,	PUNCT
admet-1586	110	31	malvern	malvern	PROPN
admet-1586	110	32	,	,	PUNCT
admet-1586	110	33	uk	uk	PROPN
admet-1586	110	34	)	)	PUNCT
admet-1586	110	35	.	.	PUNCT
admet-1586	111	1	results	result	NOUN
admet-1586	111	2	and	and	CCONJ
admet-1586	111	3	discussion	discussion	NOUN
admet-1586	111	4	hot	hot	ADJ
admet-1586	111	5	-	-	PUNCT
admet-1586	111	6	melt	melt	NOUN
admet-1586	111	7	extrusion	extrusion	NOUN
admet-1586	111	8	the	the	DET
admet-1586	111	9	physical	physical	ADJ
admet-1586	111	10	mixture	mixture	NOUN
admet-1586	111	11	of	of	ADP
admet-1586	111	12	imc	imc	PROPN
admet-1586	111	13	-	-	PUNCT
admet-1586	111	14	mg	mg	PROPN
admet-1586	111	15	(	(	PUNCT
admet-1586	111	16	20:80	20:80	NUM
admet-1586	111	17	)	)	PUNCT
admet-1586	111	18	and	and	CCONJ
admet-1586	111	19	imc	imc	PROPN
admet-1586	111	20	-	-	PUNCT
admet-1586	111	21	mx	mx	PROPN
admet-1586	111	22	(	(	PUNCT
admet-1586	111	23	20:80	20:80	NUM
admet-1586	111	24	)	)	PUNCT
admet-1586	111	25	was	be	AUX
admet-1586	111	26	subjected	subject	VERB
admet-1586	111	27	to	to	ADP
admet-1586	111	28	the	the	DET
admet-1586	111	29	hot	hot	ADJ
admet-1586	111	30	-	-	PUNCT
admet-1586	111	31	melt	melt	NOUN
admet-1586	111	32	extrusion	extrusion	NOUN
admet-1586	111	33	process	process	NOUN
admet-1586	111	34	.	.	PUNCT
admet-1586	112	1	figure	figure	NOUN
admet-1586	112	2	1	1	NUM
admet-1586	112	3	shows	show	VERB
admet-1586	112	4	the	the	DET
admet-1586	112	5	torque	torque	NOUN
admet-1586	112	6	values	value	NOUN
admet-1586	112	7	as	as	ADP
admet-1586	112	8	a	a	DET
admet-1586	112	9	function	function	NOUN
admet-1586	112	10	of	of	ADP
admet-1586	112	11	temperature	temperature	NOUN
admet-1586	112	12	for	for	ADP
admet-1586	112	13	imc	imc	PROPN
admet-1586	112	14	-	-	PUNCT
admet-1586	112	15	mg	mg	PROPN
admet-1586	112	16	(	(	PUNCT
admet-1586	112	17	20:80	20:80	NUM
admet-1586	112	18	)	)	PUNCT
admet-1586	112	19	and	and	CCONJ
admet-1586	112	20	imc	imc	PROPN
admet-1586	112	21	-	-	PUNCT
admet-1586	112	22	mx	mx	PROPN
admet-1586	112	23	(	(	PUNCT
admet-1586	112	24	20:80	20:80	NUM
admet-1586	112	25	)	)	PUNCT
admet-1586	112	26	.	.	PUNCT
admet-1586	113	1	the	the	DET
admet-1586	113	2	imc	imc	PROPN
admet-1586	113	3	-	-	PUNCT
admet-1586	113	4	mg	mg	PROPN
admet-1586	113	5	(	(	PUNCT
admet-1586	113	6	20:80	20:80	NUM
admet-1586	113	7	)	)	PUNCT
admet-1586	113	8	sample	sample	NOUN
admet-1586	113	9	was	be	AUX
admet-1586	113	10	mixed	mixed	ADJ
admet-1586	113	11	and	and	CCONJ
admet-1586	113	12	extruded	extrude	VERB
admet-1586	113	13	at	at	ADP
admet-1586	113	14	100	100	NUM
admet-1586	113	15	°	°	NOUN
admet-1586	113	16	c	c	NOUN
admet-1586	113	17	,	,	PUNCT
admet-1586	113	18	but	but	CCONJ
admet-1586	113	19	higher	high	ADJ
admet-1586	113	20	torque	torque	NOUN
admet-1586	113	21	over	over	ADP
admet-1586	113	22	2.5	2.5	NUM
admet-1586	113	23	nm	nm	NOUN
admet-1586	113	24	caused	cause	VERB
admet-1586	113	25	lower	low	ADJ
admet-1586	113	26	processability	processability	NOUN
admet-1586	113	27	;	;	PUNCT
admet-1586	113	28	the	the	DET
admet-1586	113	29	powder	powder	NOUN
admet-1586	113	30	could	could	AUX
admet-1586	113	31	not	not	PART
admet-1586	113	32	be	be	AUX
admet-1586	113	33	fed	feed	VERB
admet-1586	113	34	into	into	ADP
admet-1586	113	35	the	the	DET
admet-1586	113	36	twin	twin	ADJ
admet-1586	113	37	-	-	PUNCT
admet-1586	113	38	screw	screw	NOUN
admet-1586	113	39	barrel	barrel	NOUN
admet-1586	113	40	.	.	PUNCT
admet-1586	114	1	the	the	DET
admet-1586	114	2	temperature	temperature	NOUN
admet-1586	114	3	was	be	AUX
admet-1586	114	4	elevated	elevate	VERB
admet-1586	114	5	to	to	ADP
admet-1586	114	6	120	120	NUM
admet-1586	114	7	°	°	NOUN
admet-1586	114	8	c	c	NOUN
admet-1586	114	9	,	,	PUNCT
admet-1586	114	10	and	and	CCONJ
admet-1586	114	11	the	the	DET
admet-1586	114	12	process	process	NOUN
admet-1586	114	13	was	be	AUX
admet-1586	114	14	re	re	VERB
admet-1586	114	15	-	-	VERB
admet-1586	114	16	performed	perform	VERB
admet-1586	114	17	.	.	PUNCT
admet-1586	115	1	the	the	DET
admet-1586	115	2	torque	torque	NOUN
admet-1586	115	3	measured	measure	VERB
admet-1586	115	4	0.76	0.76	NUM
admet-1586	115	5	nm	nm	NOUN
admet-1586	115	6	and	and	CCONJ
admet-1586	115	7	subsequently	subsequently	ADV
admet-1586	115	8	decreased	decrease	VERB
admet-1586	115	9	with	with	ADP
admet-1586	115	10	each	each	DET
admet-1586	115	11	temperature	temperature	NOUN
admet-1586	115	12	elevation	elevation	NOUN
admet-1586	115	13	,	,	PUNCT
admet-1586	115	14	reaching	reach	VERB
admet-1586	115	15	0.22	0.22	NUM
admet-1586	115	16	nm	nm	NOUN
admet-1586	115	17	at	at	ADP
admet-1586	115	18	170	170	NUM
admet-1586	115	19	°	°	NOUN
admet-1586	115	20	c	c	NOUN
admet-1586	115	21	.	.	PUNCT
admet-1586	116	1	whereas	whereas	SCONJ
admet-1586	116	2	when	when	SCONJ
admet-1586	116	3	the	the	DET
admet-1586	116	4	imc	imc	PROPN
admet-1586	116	5	-	-	PUNCT
admet-1586	116	6	mx	mx	PROPN
admet-1586	116	7	sample	sample	NOUN
admet-1586	116	8	was	be	AUX
admet-1586	116	9	processed	process	VERB
admet-1586	116	10	at	at	ADP
admet-1586	116	11	100	100	NUM
admet-1586	116	12	°	°	NOUN
admet-1586	116	13	c	c	NOUN
admet-1586	116	14	,	,	PUNCT
admet-1586	116	15	the	the	DET
admet-1586	116	16	torque	torque	NOUN
admet-1586	116	17	measured	measure	VERB
admet-1586	116	18	approximately	approximately	ADV
admet-1586	116	19	0.55	0.55	NUM
admet-1586	116	20	nm	nm	NOUN
admet-1586	116	21	.	.	PUNCT
admet-1586	117	1	the	the	DET
admet-1586	117	2	torque	torque	NOUN
admet-1586	117	3	was	be	AUX
admet-1586	117	4	reduced	reduce	VERB
admet-1586	117	5	to	to	ADP
admet-1586	117	6	almost	almost	ADV
admet-1586	117	7	0.20	0.20	NUM
admet-1586	117	8	nm	nm	NOUN
admet-1586	117	9	at	at	ADP
admet-1586	117	10	120	120	NUM
admet-1586	117	11	°	°	NOUN
admet-1586	117	12	c	c	NOUN
admet-1586	117	13	.	.	PUNCT
admet-1586	118	1	previously	previously	ADV
admet-1586	118	2	,	,	PUNCT
admet-1586	118	3	an	an	DET
admet-1586	118	4	hme	hme	NOUN
admet-1586	118	5	experiment	experiment	NOUN
admet-1586	118	6	using	use	VERB
admet-1586	118	7	a	a	DET
admet-1586	118	8	mixture	mixture	NOUN
admet-1586	118	9	of	of	ADP
admet-1586	118	10	ibuprofen	ibuprofen	NOUN
admet-1586	118	11	and	and	CCONJ
admet-1586	118	12	kollidon	kollidon	PROPN
admet-1586	118	13	sr	sr	PROPN
admet-1586	118	14	observed	observe	VERB
admet-1586	118	15	a	a	DET
admet-1586	118	16	reduction	reduction	NOUN
admet-1586	118	17	of	of	ADP
admet-1586	118	18	torque	torque	NOUN
admet-1586	118	19	with	with	ADP
admet-1586	118	20	processing	processing	NOUN
admet-1586	118	21	temperature	temperature	NOUN
admet-1586	118	22	,	,	PUNCT
admet-1586	118	23	and	and	CCONJ
admet-1586	118	24	this	this	DET
admet-1586	118	25	phenomenon	phenomenon	NOUN
admet-1586	118	26	could	could	AUX
admet-1586	118	27	be	be	AUX
admet-1586	118	28	correlated	correlate	VERB
admet-1586	118	29	with	with	ADP
admet-1586	118	30	the	the	DET
admet-1586	118	31	tg	tg	PROPN
admet-1586	118	32	of	of	ADP
admet-1586	118	33	the	the	DET
admet-1586	118	34	mixture	mixture	NOUN
admet-1586	119	1	[	[	X
admet-1586	119	2	25	25	NUM
admet-1586	119	3	]	]	PUNCT
admet-1586	119	4	.	.	PUNCT
admet-1586	120	1	the	the	DET
admet-1586	120	2	tg	tg	PROPN
admet-1586	120	3	of	of	ADP
admet-1586	120	4	hpmc	hpmc	ADJ
admet-1586	120	5	-	-	PUNCT
admet-1586	120	6	mg	mg	ADJ
admet-1586	120	7	and	and	CCONJ
admet-1586	120	8	hpmc	hpmc	ADJ
admet-1586	120	9	-	-	PROPN
admet-1586	120	10	mx	mx	PROPN
admet-1586	120	11	were	be	AUX
admet-1586	120	12	121.3±1.2	121.3±1.2	NUM
admet-1586	120	13	°	°	ADP
admet-1586	120	14	c	c	NOUN
admet-1586	120	15	and	and	CCONJ
admet-1586	120	16	107.9±0.4	107.9±0.4	NUM
admet-1586	120	17	°	°	NOUN
admet-1586	120	18	c	c	NOUN
admet-1586	120	19	,	,	PUNCT
admet-1586	120	20	respectively	respectively	ADV
admet-1586	120	21	[	[	X
admet-1586	120	22	19	19	NUM
admet-1586	120	23	]	]	PUNCT
admet-1586	120	24	.	.	PUNCT
admet-1586	121	1	the	the	DET
admet-1586	121	2	observed	observe	VERB
admet-1586	121	3	rapid	rapid	ADJ
admet-1586	121	4	reduction	reduction	NOUN
admet-1586	121	5	of	of	ADP
admet-1586	121	6	torque	torque	NOUN
admet-1586	121	7	at	at	ADP
admet-1586	121	8	temperatures	temperature	NOUN
admet-1586	121	9	over	over	ADP
admet-1586	121	10	120	120	NUM
admet-1586	121	11	°	°	NUM
admet-1586	121	12	c	c	NOUN
admet-1586	121	13	was	be	AUX
admet-1586	121	14	caused	cause	VERB
admet-1586	121	15	by	by	ADP
admet-1586	121	16	the	the	DET
admet-1586	121	17	mixtures	mixture	NOUN
admet-1586	121	18	reaching	reach	VERB
admet-1586	121	19	the	the	DET
admet-1586	121	20	glass	glass	NOUN
admet-1586	121	21	transition	transition	NOUN
admet-1586	121	22	temperature	temperature	NOUN
admet-1586	121	23	of	of	ADP
admet-1586	121	24	hpmcas	hpmca	NOUN
admet-1586	121	25	followed	follow	VERB
admet-1586	121	26	by	by	ADP
admet-1586	121	27	melting	melting	NOUN
admet-1586	121	28	of	of	ADP
admet-1586	121	29	imc	imc	PROPN
admet-1586	121	30	.	.	PUNCT
admet-1586	122	1	these	these	DET
admet-1586	122	2	results	result	NOUN
admet-1586	122	3	suggest	suggest	VERB
admet-1586	122	4	that	that	SCONJ
admet-1586	122	5	hpmcasmx	hpmcasmx	PROPN
admet-1586	122	6	can	can	AUX
admet-1586	122	7	be	be	AUX
admet-1586	122	8	effectively	effectively	ADV
admet-1586	122	9	used	use	VERB
admet-1586	122	10	in	in	ADP
admet-1586	122	11	the	the	DET
admet-1586	122	12	hot	hot	ADJ
admet-1586	122	13	-	-	PUNCT
admet-1586	122	14	melt	melt	NOUN
admet-1586	122	15	extrusion	extrusion	NOUN
admet-1586	122	16	process	process	NOUN
admet-1586	122	17	for	for	ADP
admet-1586	122	18	the	the	DET
admet-1586	122	19	preparation	preparation	NOUN
admet-1586	122	20	of	of	ADP
admet-1586	122	21	solid	solid	ADJ
admet-1586	122	22	dispersion	dispersion	NOUN
admet-1586	122	23	at	at	ADP
admet-1586	122	24	a	a	DET
admet-1586	122	25	relatively	relatively	ADV
admet-1586	122	26	lower	low	ADJ
admet-1586	122	27	temperature	temperature	NOUN
admet-1586	122	28	than	than	ADP
admet-1586	122	29	hpmcas	hpmca	NOUN
admet-1586	122	30	-	-	PUNCT
admet-1586	122	31	mg	mg	PROPN
admet-1586	123	1	.	.	PUNCT
admet-1586	123	2	temperature	temperature	NOUN
admet-1586	123	3	,	,	PUNCT
admet-1586	123	4	°	°	ADP
admet-1586	123	5	c	c	NOUN
admet-1586	123	6	figure	figure	NOUN
admet-1586	123	7	1	1	NUM
admet-1586	123	8	.	.	PUNCT
admet-1586	124	1	torque	torque	NOUN
admet-1586	124	2	monitoring	monitoring	NOUN
admet-1586	124	3	during	during	ADP
admet-1586	124	4	hot	hot	ADJ
admet-1586	124	5	-	-	PUNCT
admet-1586	124	6	melt	melt	NOUN
admet-1586	124	7	extrusion	extrusion	NOUN
admet-1586	124	8	of	of	ADP
admet-1586	124	9	imc	imc	PROPN
admet-1586	124	10	-	-	PUNCT
admet-1586	124	11	mg	mg	PROPN
admet-1586	124	12	(	(	PUNCT
admet-1586	124	13	20:80	20:80	NUM
admet-1586	124	14	)	)	PUNCT
admet-1586	124	15	and	and	CCONJ
admet-1586	124	16	imc	imc	PROPN
admet-1586	124	17	-	-	PUNCT
admet-1586	124	18	mx	mx	PROPN
admet-1586	124	19	(	(	PUNCT
admet-1586	124	20	20:80	20:80	NUM
admet-1586	124	21	)	)	PUNCT
admet-1586	124	22	at	at	ADP
admet-1586	124	23	100	100	NUM
admet-1586	124	24	-	-	SYM
admet-1586	124	25	170	170	NUM
admet-1586	124	26	°	°	PROPN
admet-1586	124	27	c	c	NOUN
admet-1586	124	28	.	.	PUNCT
admet-1586	125	1	figure	figure	NOUN
admet-1586	125	2	2	2	NUM
admet-1586	125	3	shows	show	VERB
admet-1586	125	4	the	the	DET
admet-1586	125	5	appearance	appearance	NOUN
admet-1586	125	6	of	of	ADP
admet-1586	125	7	the	the	DET
admet-1586	125	8	hot	hot	ADJ
admet-1586	125	9	-	-	PUNCT
admet-1586	125	10	melt	melt	NOUN
admet-1586	125	11	extrudate	extrudate	NOUN
admet-1586	125	12	imc	imc	PROPN
admet-1586	125	13	-	-	PUNCT
admet-1586	125	14	mg	mg	PROPN
admet-1586	125	15	(	(	PUNCT
admet-1586	125	16	20:80	20:80	NUM
admet-1586	125	17	)	)	PUNCT
admet-1586	125	18	and	and	CCONJ
admet-1586	125	19	imc	imc	PROPN
admet-1586	125	20	-	-	PUNCT
admet-1586	125	21	mx	mx	PROPN
admet-1586	125	22	(	(	PUNCT
admet-1586	125	23	20:80	20:80	NUM
admet-1586	125	24	)	)	PUNCT
admet-1586	125	25	processed	process	VERB
admet-1586	125	26	at	at	ADP
admet-1586	125	27	120	120	NUM
admet-1586	125	28	°	°	NOUN
admet-1586	125	29	c	c	NOUN
admet-1586	125	30	.	.	PUNCT
admet-1586	126	1	the	the	DET
admet-1586	126	2	imc	imc	PROPN
admet-1586	126	3	-	-	PUNCT
admet-1586	126	4	mg	mg	PROPN
admet-1586	126	5	(	(	PUNCT
admet-1586	126	6	20:80	20:80	NUM
admet-1586	126	7	)	)	PUNCT
admet-1586	126	8	extrudate	extrudate	NOUN
admet-1586	126	9	was	be	AUX
admet-1586	126	10	characterized	characterize	VERB
admet-1586	126	11	by	by	ADP
admet-1586	126	12	a	a	DET
admet-1586	126	13	visible	visible	ADJ
admet-1586	126	14	dispersion	dispersion	NOUN
admet-1586	126	15	of	of	ADP
admet-1586	126	16	white	white	ADJ
admet-1586	126	17	powder	powder	NOUN
admet-1586	126	18	in	in	ADP
admet-1586	126	19	the	the	DET
admet-1586	126	20	extrudate	extrudate	NOUN
admet-1586	126	21	.	.	PUNCT
admet-1586	127	1	in	in	ADP
admet-1586	127	2	contrast	contrast	NOUN
admet-1586	127	3	,	,	PUNCT
admet-1586	127	4	imc	imc	PROPN
admet-1586	127	5	-	-	PUNCT
admet-1586	127	6	mx	mx	PROPN
admet-1586	127	7	(	(	PUNCT
admet-1586	127	8	20:80	20:80	NUM
admet-1586	127	9	)	)	PUNCT
admet-1586	127	10	produced	produce	VERB
admet-1586	127	11	a	a	DET
admet-1586	127	12	translucent	translucent	ADJ
admet-1586	127	13	yellow	yellow	ADJ
admet-1586	127	14	extrudate	extrudate	NOUN
admet-1586	127	15	.	.	PUNCT
admet-1586	128	1	the	the	DET
admet-1586	128	2	glass	glass	NOUN
admet-1586	128	3	transition	transition	NOUN
admet-1586	128	4	of	of	ADP
admet-1586	128	5	imc	imc	PROPN
admet-1586	128	6	results	result	NOUN
admet-1586	128	7	in	in	ADP
admet-1586	128	8	a	a	DET
admet-1586	128	9	change	change	NOUN
admet-1586	128	10	in	in	ADP
admet-1586	128	11	appearance	appearance	NOUN
admet-1586	128	12	and	and	CCONJ
admet-1586	128	13	a	a	DET
admet-1586	128	14	yellow	yellow	ADJ
admet-1586	128	15	-	-	PUNCT
admet-1586	128	16	glassy	glassy	NOUN
admet-1586	128	17	appearance	appearance	NOUN
admet-1586	128	18	is	be	AUX
admet-1586	128	19	formed	form	VERB
admet-1586	128	20	by	by	ADP
admet-1586	128	21	the	the	DET
admet-1586	128	22	disruption	disruption	NOUN
admet-1586	128	23	of	of	ADP
admet-1586	128	24	the	the	DET
admet-1586	128	25	crystal	crystal	NOUN
admet-1586	128	26	lattice	lattice	NOUN
admet-1586	128	27	due	due	ADP
admet-1586	128	28	to	to	ADP
admet-1586	128	29	a	a	DET
admet-1586	128	30	change	change	NOUN
admet-1586	128	31	in	in	ADP
admet-1586	128	32	the	the	DET
admet-1586	128	33	form	form	NOUN
admet-1586	128	34	of	of	ADP
admet-1586	128	35	the	the	DET
admet-1586	128	36	intermolecular	intermolecular	ADJ
admet-1586	128	37	interaction	interaction	NOUN
admet-1586	128	38	between	between	ADP
admet-1586	128	39	functional	functional	ADJ
admet-1586	128	40	groups	group	NOUN
admet-1586	128	41	[	[	X
admet-1586	128	42	26	26	NUM
admet-1586	128	43	-	-	SYM
admet-1586	128	44	27	27	NUM
admet-1586	128	45	]	]	PUNCT
admet-1586	128	46	.	.	PUNCT
admet-1586	129	1	therefore	therefore	ADV
admet-1586	129	2	,	,	PUNCT
admet-1586	129	3	it	it	PRON
admet-1586	129	4	suggests	suggest	VERB
admet-1586	129	5	a	a	DET
admet-1586	129	6	possibility	possibility	NOUN
admet-1586	129	7	of	of	ADP
admet-1586	129	8	partial	partial	ADJ
admet-1586	129	9	or	or	CCONJ
admet-1586	129	10	complete	complete	ADJ
admet-1586	129	11	amorphization	amorphization	NOUN
admet-1586	129	12	with	with	ADP
admet-1586	129	13	the	the	DET
admet-1586	129	14	carrier	carrier	NOUN
admet-1586	129	15	after	after	ADP
admet-1586	129	16	hot	hot	ADJ
admet-1586	129	17	-	-	PUNCT
admet-1586	129	18	melt	melt	NOUN
admet-1586	129	19	extrusion	extrusion	NOUN
admet-1586	129	20	.	.	PUNCT
admet-1586	130	1	these	these	DET
admet-1586	130	2	results	result	NOUN
admet-1586	130	3	were	be	AUX
admet-1586	130	4	consistent	consistent	ADJ
admet-1586	130	5	with	with	ADP
admet-1586	130	6	the	the	DET
admet-1586	130	7	change	change	NOUN
admet-1586	130	8	in	in	ADP
admet-1586	130	9	the	the	DET
admet-1586	130	10	torque	torque	NOUN
admet-1586	130	11	during	during	ADP
admet-1586	130	12	the	the	DET
admet-1586	130	13	hot	hot	ADJ
admet-1586	130	14	-	-	PUNCT
admet-1586	130	15	melt	melt	NOUN
admet-1586	130	16	extrusion	extrusion	NOUN
admet-1586	130	17	process	process	NOUN
admet-1586	130	18	shown	show	VERB
admet-1586	130	19	in	in	ADP
admet-1586	130	20	figure	figure	NOUN
admet-1586	130	21	1	1	NUM
admet-1586	130	22	.	.	PUNCT
admet-1586	131	1	imc	imc	PROPN
admet-1586	131	2	-	-	PUNCT
admet-1586	131	3	mg	mg	PROPN
admet-1586	131	4	(	(	PUNCT
admet-1586	131	5	20:80	20:80	NUM
admet-1586	131	6	)	)	PUNCT
admet-1586	131	7	required	require	VERB
admet-1586	131	8	over	over	ADP
admet-1586	131	9	150	150	NUM
admet-1586	131	10	°	°	NOUN
admet-1586	131	11	c	c	NOUN
admet-1586	131	12	to	to	PART
admet-1586	131	13	reach	reach	VERB
admet-1586	131	14	a	a	DET
admet-1586	131	15	plateau	plateau	NOUN
admet-1586	131	16	in	in	ADP
admet-1586	131	17	torque	torque	NOUN
admet-1586	131	18	reduction	reduction	NOUN
admet-1586	131	19	,	,	PUNCT
admet-1586	131	20	while	while	SCONJ
admet-1586	131	21	imcmx	imcmx	NOUN
admet-1586	131	22	(	(	PUNCT
admet-1586	131	23	20:80	20:80	NUM
admet-1586	131	24	)	)	PUNCT
admet-1586	131	25	only	only	ADV
admet-1586	131	26	required	require	VERB
admet-1586	131	27	120	120	NUM
admet-1586	131	28	°	°	NOUN
admet-1586	131	29	c	c	NOUN
admet-1586	131	30	.	.	PUNCT
admet-1586	132	1	t	t	NOUN
admet-1586	132	2	o	o	X
admet-1586	132	3	rq	rq	VERB
admet-1586	132	4	u	u	X
admet-1586	132	5	e	e	X
admet-1586	132	6	(	(	PUNCT
admet-1586	132	7	n	n	X
admet-1586	132	8	m	m	NOUN
admet-1586	132	9	)	)	PUNCT
admet-1586	132	10	temperature	temperature	NOUN
admet-1586	132	11	(	(	PUNCT
admet-1586	132	12	c	c	PROPN
admet-1586	132	13	)	)	PUNCT
admet-1586	132	14	90	90	NUM
admet-1586	132	15	180120	180120	NUM
admet-1586	132	16	150	150	NUM
admet-1586	132	17	●	●	NUM
admet-1586	132	18	imc	imc	NOUN
admet-1586	132	19	-	-	PUNCT
admet-1586	132	20	mg	mg	PROPN
admet-1586	132	21	(	(	PUNCT
admet-1586	132	22	20:80	20:80	NUM
admet-1586	132	23	)	)	PUNCT
admet-1586	132	24	●	●	PUNCT
admet-1586	132	25	imc	imc	PROPN
admet-1586	132	26	-	-	PUNCT
admet-1586	132	27	mx	mx	PROPN
admet-1586	132	28	(	(	PUNCT
admet-1586	132	29	20:80	20:80	NUM
admet-1586	132	30	)	)	PUNCT
admet-1586	132	31	0.0	0.0	NUM
admet-1586	132	32	0.2	0.2	NUM
admet-1586	132	33	0.4	0.4	NUM
admet-1586	132	34	0.6	0.6	NUM
admet-1586	132	35	0.8	0.8	NUM
admet-1586	132	36	1.0	1.0	NUM
admet-1586	132	37	to	to	PART
admet-1586	132	38	rq	rq	VERB
admet-1586	132	39	u	u	PROPN
admet-1586	132	40	e	e	PROPN
admet-1586	132	41	,	,	PUNCT
admet-1586	132	42	n	n	PRON
admet-1586	133	1	m	m	PROPN
admet-1586	133	2	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	NOUN
admet-1586	133	3	h.	h.	PROPN
admet-1586	133	4	tanaka	tanaka	PROPN
admet-1586	133	5	et	et	PROPN
admet-1586	133	6	al	al	PROPN
admet-1586	133	7	.	.	PROPN
admet-1586	133	8	admet	admet	PROPN
admet-1586	133	9	&	&	CCONJ
admet-1586	133	10	dmpk	dmpk	PROPN
admet-1586	133	11	11(3	11(3	NUM
admet-1586	133	12	)	)	PUNCT
admet-1586	133	13	(	(	PUNCT
admet-1586	133	14	2023	2023	NUM
admet-1586	133	15	)	)	PUNCT
admet-1586	133	16	373	373	NUM
admet-1586	133	17	-	-	SYM
admet-1586	133	18	385	385	NUM
admet-1586	133	19	378	378	NUM
admet-1586	133	20	figure	figure	NOUN
admet-1586	133	21	2	2	NUM
admet-1586	133	22	.	.	NOUN
admet-1586	133	23	appearance	appearance	NOUN
admet-1586	133	24	of	of	ADP
admet-1586	133	25	hot	hot	ADJ
admet-1586	133	26	-	-	PUNCT
admet-1586	133	27	melt	melt	NOUN
admet-1586	133	28	extruded	extrude	VERB
admet-1586	133	29	imc	imc	NOUN
admet-1586	133	30	-	-	PUNCT
admet-1586	133	31	mg	mg	PROPN
admet-1586	133	32	(	(	PUNCT
admet-1586	133	33	20:80	20:80	NUM
admet-1586	133	34	)	)	PUNCT
admet-1586	133	35	and	and	CCONJ
admet-1586	133	36	imc	imc	PROPN
admet-1586	133	37	-	-	PUNCT
admet-1586	133	38	mx	mx	PROPN
admet-1586	133	39	(	(	PUNCT
admet-1586	133	40	20:80	20:80	NUM
admet-1586	133	41	)	)	PUNCT
admet-1586	133	42	processed	process	VERB
admet-1586	133	43	at	at	ADP
admet-1586	133	44	120	120	NUM
admet-1586	133	45	°	°	NOUN
admet-1586	133	46	c	c	NOUN
admet-1586	133	47	.	.	PUNCT
admet-1586	134	1	to	to	PART
admet-1586	134	2	confirm	confirm	VERB
admet-1586	134	3	if	if	SCONJ
admet-1586	134	4	the	the	DET
admet-1586	134	5	dispersed	disperse	VERB
admet-1586	134	6	white	white	ADJ
admet-1586	134	7	powder	powder	NOUN
admet-1586	134	8	was	be	AUX
admet-1586	134	9	crystalline	crystalline	ADJ
admet-1586	134	10	imc	imc	PROPN
admet-1586	134	11	,	,	PUNCT
admet-1586	134	12	raman	raman	NOUN
admet-1586	134	13	mapping	mapping	NOUN
admet-1586	134	14	was	be	AUX
admet-1586	134	15	performed	perform	VERB
admet-1586	134	16	as	as	ADP
admet-1586	134	17	a	a	DET
admet-1586	134	18	nondestructive	nondestructive	ADJ
admet-1586	134	19	method	method	NOUN
admet-1586	134	20	,	,	PUNCT
admet-1586	134	21	as	as	SCONJ
admet-1586	134	22	the	the	DET
admet-1586	134	23	milling	milling	NOUN
admet-1586	134	24	process	process	NOUN
admet-1586	134	25	for	for	ADP
admet-1586	134	26	the	the	DET
admet-1586	134	27	preparation	preparation	NOUN
admet-1586	134	28	of	of	ADP
admet-1586	134	29	powder	powder	NOUN
admet-1586	134	30	to	to	PART
admet-1586	134	31	be	be	AUX
admet-1586	134	32	measured	measure	VERB
admet-1586	134	33	by	by	ADP
admet-1586	134	34	xrpd	xrpd	PROPN
admet-1586	134	35	might	might	AUX
admet-1586	134	36	cause	cause	VERB
admet-1586	134	37	amorphization	amorphization	NOUN
admet-1586	134	38	[	[	X
admet-1586	134	39	28	28	NUM
admet-1586	134	40	]	]	PUNCT
admet-1586	134	41	.	.	PUNCT
admet-1586	135	1	figure	figure	NOUN
admet-1586	135	2	3a	3a	PROPN
admet-1586	135	3	shows	show	VERB
admet-1586	135	4	the	the	DET
admet-1586	135	5	raman	raman	NOUN
admet-1586	135	6	images	image	NOUN
admet-1586	135	7	of	of	ADP
admet-1586	135	8	the	the	DET
admet-1586	135	9	cutting	cut	VERB
admet-1586	135	10	plane	plane	NOUN
admet-1586	135	11	of	of	ADP
admet-1586	135	12	the	the	DET
admet-1586	135	13	hot	hot	ADJ
admet-1586	135	14	-	-	PUNCT
admet-1586	135	15	melt	melt	NOUN
admet-1586	135	16	extrude	extrude	NOUN
admet-1586	135	17	processed	process	VERB
admet-1586	135	18	at	at	ADP
admet-1586	135	19	120	120	NUM
admet-1586	135	20	°	°	NOUN
admet-1586	135	21	c	c	NOUN
admet-1586	135	22	.	.	PUNCT
admet-1586	136	1	(	(	PUNCT
admet-1586	136	2	a	a	X
admet-1586	136	3	)	)	PUNCT
admet-1586	136	4	(	(	PUNCT
admet-1586	136	5	b	b	X
admet-1586	136	6	)	)	PUNCT
admet-1586	136	7	(	(	PUNCT
admet-1586	136	8	c	c	X
admet-1586	136	9	)	)	PUNCT
admet-1586	136	10	raman	raman	NOUN
admet-1586	136	11	shift	shift	NOUN
admet-1586	136	12	,	,	PUNCT
admet-1586	136	13	cm-1	cm-1	PUNCT
admet-1586	136	14	figure	figure	NOUN
admet-1586	136	15	3	3	NUM
admet-1586	136	16	.	.	PUNCT
admet-1586	136	17	raman	raman	NOUN
admet-1586	136	18	images	image	NOUN
admet-1586	136	19	of	of	ADP
admet-1586	136	20	imc	imc	PROPN
admet-1586	136	21	-	-	PUNCT
admet-1586	136	22	mg	mg	PROPN
admet-1586	136	23	(	(	PUNCT
admet-1586	136	24	20:80	20:80	NUM
admet-1586	136	25	)	)	PUNCT
admet-1586	136	26	and	and	CCONJ
admet-1586	136	27	imc	imc	PROPN
admet-1586	136	28	-	-	PUNCT
admet-1586	136	29	mx	mx	PROPN
admet-1586	136	30	(	(	PUNCT
admet-1586	136	31	20:80	20:80	NUM
admet-1586	136	32	)	)	PUNCT
admet-1586	136	33	processed	process	VERB
admet-1586	136	34	at	at	ADP
admet-1586	136	35	(	(	PUNCT
admet-1586	136	36	a	a	X
admet-1586	136	37	)	)	PUNCT
admet-1586	136	38	120	120	NUM
admet-1586	136	39	°	°	NUM
admet-1586	136	40	c	c	NOUN
admet-1586	136	41	and	and	CCONJ
admet-1586	136	42	(	(	PUNCT
admet-1586	136	43	b	b	NOUN
admet-1586	136	44	)	)	PUNCT
admet-1586	136	45	170	170	NUM
admet-1586	137	1	°	°	NOUN
admet-1586	137	2	c	c	X
admet-1586	137	3	,	,	PUNCT
admet-1586	137	4	and	and	CCONJ
admet-1586	137	5	raman	raman	VERB
admet-1586	137	6	spectra	spectra	NOUN
admet-1586	137	7	of	of	ADP
admet-1586	137	8	(	(	PUNCT
admet-1586	137	9	c	c	NOUN
admet-1586	137	10	)	)	PUNCT
admet-1586	137	11	points	point	VERB
admet-1586	137	12	a	a	DET
admet-1586	137	13	-	-	PUNCT
admet-1586	137	14	d	d	NOUN
admet-1586	137	15	in	in	ADP
admet-1586	137	16	the	the	DET
admet-1586	137	17	raman	raman	NOUN
admet-1586	137	18	images	image	NOUN
admet-1586	137	19	.	.	PUNCT
admet-1586	138	1	imc	imc	PROPN
admet-1586	138	2	-	-	PUNCT
admet-1586	138	3	mg	mg	PROPN
admet-1586	138	4	(	(	PUNCT
admet-1586	138	5	20:80	20:80	NUM
admet-1586	138	6	)	)	PUNCT
admet-1586	138	7	at	at	ADP
admet-1586	138	8	120c	120c	NUM
admet-1586	138	9	imc	imc	PROPN
admet-1586	138	10	-	-	PUNCT
admet-1586	138	11	mx	mx	PROPN
admet-1586	138	12	(	(	PUNCT
admet-1586	138	13	20:80	20:80	NUM
admet-1586	138	14	)	)	PUNCT
admet-1586	138	15	at	at	ADP
admet-1586	138	16	120c	120c	NUM
admet-1586	138	17	imc	imc	PROPN
admet-1586	138	18	-	-	PUNCT
admet-1586	138	19	mg	mg	PROPN
admet-1586	138	20	(	(	PUNCT
admet-1586	138	21	20:80	20:80	NUM
admet-1586	138	22	)	)	PUNCT
admet-1586	138	23	at	at	ADP
admet-1586	138	24	120c	120c	NUM
admet-1586	138	25	imc	imc	PROPN
admet-1586	138	26	-	-	PUNCT
admet-1586	138	27	mx	mx	PROPN
admet-1586	138	28	(	(	PUNCT
admet-1586	138	29	20:80	20:80	NUM
admet-1586	138	30	)	)	PUNCT
admet-1586	138	31	at	at	ADP
admet-1586	138	32	120c	120c	NUM
admet-1586	138	33	2.5	2.5	NUM
admet-1586	138	34	0.2	0.2	NUM
admet-1586	138	35	3.4	3.4	NUM
admet-1586	138	36	-1.5	-1.5	NUM
admet-1586	138	37	50	50	NUM
admet-1586	138	38	µm	µm	ADP
admet-1586	138	39	point	point	NOUN
admet-1586	138	40	a	a	DET
admet-1586	138	41	point	point	NOUN
admet-1586	138	42	b	b	NOUN
admet-1586	138	43	point	point	NOUN
admet-1586	138	44	c	c	NOUN
admet-1586	138	45	point	point	NOUN
admet-1586	138	46	d	d	NOUN
admet-1586	138	47	50	50	NUM
admet-1586	138	48	µm	µm	ADP
admet-1586	138	49	imc	imc	PROPN
admet-1586	138	50	-	-	PUNCT
admet-1586	138	51	mg	mg	PROPN
admet-1586	138	52	(	(	PUNCT
admet-1586	138	53	20:80	20:80	NUM
admet-1586	138	54	)	)	PUNCT
admet-1586	138	55	at	at	ADP
admet-1586	138	56	170c	170c	NUM
admet-1586	138	57	imc	imc	PROPN
admet-1586	138	58	-	-	PUNCT
admet-1586	138	59	mx	mx	PROPN
admet-1586	138	60	(	(	PUNCT
admet-1586	138	61	20:80	20:80	NUM
admet-1586	138	62	)	)	PUNCT
admet-1586	138	63	at	at	ADP
admet-1586	138	64	170c	170c	NUM
admet-1586	138	65	2.5	2.5	NUM
admet-1586	138	66	-1.1	-1.1	NOUN
admet-1586	138	67	1.7	1.7	NUM
admet-1586	138	68	-0.1	-0.1	NOUN
admet-1586	138	69	50	50	NUM
admet-1586	138	70	µm	µm	PART
admet-1586	138	71	50	50	NUM
admet-1586	138	72	µm	µm	NOUN
admet-1586	138	73	in	in	ADP
admet-1586	138	74	te	te	ADP
admet-1586	138	75	n	n	PROPN
admet-1586	138	76	s	s	PART
admet-1586	138	77	it	it	PRON
admet-1586	138	78	y	y	PROPN
admet-1586	138	79	raman	raman	NOUN
admet-1586	138	80	shift	shift	NOUN
admet-1586	138	81	(	(	PUNCT
admet-1586	138	82	cm-1	cm-1	NOUN
admet-1586	138	83	)	)	PUNCT
admet-1586	138	84	1500	1500	NUM
admet-1586	138	85	18001700	18001700	NUM
admet-1586	138	86	point	point	NOUN
admet-1586	138	87	a	a	DET
admet-1586	138	88	point	point	NOUN
admet-1586	138	89	b	b	NOUN
admet-1586	138	90	point	point	NOUN
admet-1586	138	91	c	c	NOUN
admet-1586	138	92	point	point	NOUN
admet-1586	139	1	d	d	PROPN
admet-1586	139	2	1600	1600	NUM
admet-1586	139	3	1700	1700	NUM
admet-1586	139	4	cm-1	cm-1	PART
admet-1586	139	5	admet	admet	PROPN
admet-1586	139	6	&	&	CCONJ
admet-1586	139	7	dmpk	dmpk	PROPN
admet-1586	139	8	11(3	11(3	NUM
admet-1586	139	9	)	)	PUNCT
admet-1586	139	10	(	(	PUNCT
admet-1586	139	11	2023	2023	NUM
admet-1586	139	12	)	)	PUNCT
admet-1586	139	13	373	373	NUM
admet-1586	139	14	-	-	SYM
admet-1586	139	15	385	385	NUM
admet-1586	139	16	dissolution	dissolution	NOUN
admet-1586	139	17	-	-	PUNCT
admet-1586	139	18	permeation	permeation	NOUN
admet-1586	139	19	of	of	ADP
admet-1586	139	20	hot	hot	ADJ
admet-1586	139	21	-	-	PUNCT
admet-1586	139	22	melt	melt	NOUN
admet-1586	139	23	extruded	extrude	VERB
admet-1586	139	24	asd	asd	NOUN
admet-1586	139	25	doi	doi	PROPN
admet-1586	139	26	:	:	PUNCT
admet-1586	139	27	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	NOUN
admet-1586	139	28	379	379	NUM
admet-1586	139	29	the	the	DET
admet-1586	139	30	images	image	NOUN
admet-1586	139	31	were	be	AUX
admet-1586	139	32	drawn	draw	VERB
admet-1586	139	33	using	use	VERB
admet-1586	139	34	the	the	DET
admet-1586	139	35	peak	peak	NOUN
admet-1586	139	36	ratio	ratio	NOUN
admet-1586	139	37	of	of	ADP
admet-1586	139	38	crystalline	crystalline	NOUN
admet-1586	139	39	and	and	CCONJ
admet-1586	139	40	amorphous	amorphous	ADJ
admet-1586	139	41	imc	imc	PROPN
admet-1586	139	42	;	;	PUNCT
admet-1586	139	43	the	the	DET
admet-1586	139	44	lower	low	ADJ
admet-1586	139	45	intensity	intensity	NOUN
admet-1586	139	46	is	be	AUX
admet-1586	139	47	represented	represent	VERB
admet-1586	139	48	as	as	ADP
admet-1586	139	49	dark	dark	ADJ
admet-1586	139	50	gray	gray	ADJ
admet-1586	139	51	and	and	CCONJ
admet-1586	139	52	reflects	reflect	VERB
admet-1586	139	53	crystalline	crystalline	PROPN
admet-1586	139	54	imc	imc	PROPN
admet-1586	139	55	.	.	PUNCT
admet-1586	140	1	the	the	DET
admet-1586	140	2	distribution	distribution	NOUN
admet-1586	140	3	image	image	NOUN
admet-1586	140	4	of	of	ADP
admet-1586	140	5	imc	imc	PROPN
admet-1586	140	6	-	-	PUNCT
admet-1586	140	7	mg	mg	PROPN
admet-1586	140	8	(	(	PUNCT
admet-1586	140	9	20:80	20:80	NUM
admet-1586	140	10	)	)	PUNCT
admet-1586	140	11	revealed	reveal	VERB
admet-1586	140	12	that	that	SCONJ
admet-1586	140	13	crystalline	crystalline	PROPN
admet-1586	140	14	imc	imc	PROPN
admet-1586	140	15	remained	remain	VERB
admet-1586	140	16	and	and	CCONJ
admet-1586	140	17	was	be	AUX
admet-1586	140	18	heterogeneously	heterogeneously	ADV
admet-1586	140	19	dispersed	disperse	VERB
admet-1586	140	20	in	in	ADP
admet-1586	140	21	the	the	DET
admet-1586	140	22	extrude	extrude	NOUN
admet-1586	140	23	.	.	PUNCT
admet-1586	141	1	however	however	ADV
admet-1586	141	2	,	,	PUNCT
admet-1586	141	3	crystalline	crystalline	PROPN
admet-1586	141	4	imc	imc	PROPN
admet-1586	141	5	did	do	AUX
admet-1586	141	6	not	not	PART
admet-1586	141	7	appear	appear	VERB
admet-1586	141	8	in	in	ADP
admet-1586	141	9	imc	imc	PROPN
admet-1586	141	10	-	-	PUNCT
admet-1586	141	11	mx	mx	PROPN
admet-1586	141	12	(	(	PUNCT
admet-1586	141	13	20:80	20:80	NUM
admet-1586	141	14	)	)	PUNCT
admet-1586	141	15	,	,	PUNCT
admet-1586	141	16	and	and	CCONJ
admet-1586	141	17	homogenous	homogenous	ADJ
admet-1586	141	18	dispersion	dispersion	NOUN
admet-1586	141	19	of	of	ADP
admet-1586	141	20	amorphous	amorphous	ADJ
admet-1586	141	21	imc	imc	PROPN
admet-1586	141	22	into	into	ADP
admet-1586	141	23	the	the	DET
admet-1586	141	24	extrude	extrude	NOUN
admet-1586	141	25	was	be	AUX
admet-1586	141	26	shown	show	VERB
admet-1586	141	27	.	.	PUNCT
admet-1586	142	1	the	the	DET
admet-1586	142	2	results	result	NOUN
admet-1586	142	3	showed	show	VERB
admet-1586	142	4	that	that	SCONJ
admet-1586	142	5	imc	imc	PROPN
admet-1586	142	6	-	-	PUNCT
admet-1586	142	7	mx	mx	PROPN
admet-1586	142	8	(	(	PUNCT
admet-1586	142	9	20:80	20:80	NUM
admet-1586	142	10	)	)	PUNCT
admet-1586	142	11	could	could	AUX
admet-1586	142	12	be	be	AUX
admet-1586	142	13	transformed	transform	VERB
admet-1586	142	14	to	to	ADP
admet-1586	142	15	solid	solid	ADJ
admet-1586	142	16	dispersion	dispersion	NOUN
admet-1586	142	17	by	by	ADP
admet-1586	142	18	processing	process	VERB
admet-1586	142	19	at	at	ADP
admet-1586	142	20	120	120	NUM
admet-1586	142	21	°	°	NOUN
admet-1586	142	22	c	c	NOUN
admet-1586	142	23	,	,	PUNCT
admet-1586	142	24	but	but	CCONJ
admet-1586	142	25	imcmg	imcmg	NOUN
admet-1586	142	26	(	(	PUNCT
admet-1586	142	27	20:80	20:80	NUM
admet-1586	142	28	)	)	PUNCT
admet-1586	142	29	could	could	AUX
admet-1586	142	30	not	not	PART
admet-1586	142	31	.	.	PUNCT
admet-1586	143	1	this	this	DET
admet-1586	143	2	temperature	temperature	NOUN
admet-1586	143	3	was	be	AUX
admet-1586	143	4	lower	low	ADJ
admet-1586	143	5	than	than	ADP
admet-1586	143	6	the	the	DET
admet-1586	143	7	reported	report	VERB
admet-1586	143	8	values	value	NOUN
admet-1586	143	9	;	;	PUNCT
admet-1586	143	10	the	the	DET
admet-1586	143	11	study	study	NOUN
admet-1586	143	12	of	of	ADP
admet-1586	143	13	hot	hot	ADJ
admet-1586	143	14	-	-	PUNCT
admet-1586	143	15	melt	melt	NOUN
admet-1586	143	16	extrusion	extrusion	NOUN
admet-1586	143	17	using	use	VERB
admet-1586	143	18	hpmcas	hpmca	NOUN
admet-1586	143	19	set	set	VERB
admet-1586	143	20	the	the	DET
admet-1586	143	21	process	process	NOUN
admet-1586	143	22	temperature	temperature	NOUN
admet-1586	143	23	above	above	ADP
admet-1586	143	24	the	the	DET
admet-1586	143	25	tg	tg	PROPN
admet-1586	143	26	at	at	ADP
admet-1586	143	27	over	over	ADP
admet-1586	143	28	130	130	NUM
admet-1586	143	29	°	°	NOUN
admet-1586	143	30	c	c	NOUN
admet-1586	143	31	[	[	X
admet-1586	143	32	29,30	29,30	NUM
admet-1586	143	33	]	]	PUNCT
admet-1586	143	34	.	.	PUNCT
admet-1586	144	1	figure	figure	NOUN
admet-1586	144	2	3b	3b	PROPN
admet-1586	144	3	shows	show	VERB
admet-1586	144	4	the	the	DET
admet-1586	144	5	raman	raman	NOUN
admet-1586	144	6	images	image	NOUN
admet-1586	144	7	of	of	ADP
admet-1586	144	8	the	the	DET
admet-1586	144	9	cutting	cut	VERB
admet-1586	144	10	plane	plane	NOUN
admet-1586	144	11	of	of	ADP
admet-1586	144	12	the	the	DET
admet-1586	144	13	hot	hot	ADJ
admet-1586	144	14	-	-	PUNCT
admet-1586	144	15	melt	melt	NOUN
admet-1586	144	16	extrude	extrude	NOUN
admet-1586	144	17	processed	process	VERB
admet-1586	144	18	at	at	ADP
admet-1586	144	19	170	170	NUM
admet-1586	144	20	°	°	NOUN
admet-1586	144	21	c	c	NOUN
admet-1586	144	22	.	.	PUNCT
admet-1586	145	1	both	both	CCONJ
admet-1586	145	2	the	the	DET
admet-1586	145	3	hot	hot	ADJ
admet-1586	145	4	-	-	PUNCT
admet-1586	145	5	melt	melt	NOUN
admet-1586	145	6	extrude	extrude	NOUN
admet-1586	145	7	of	of	ADP
admet-1586	145	8	imc	imc	PROPN
admet-1586	145	9	-	-	PUNCT
admet-1586	145	10	mg	mg	PROPN
admet-1586	145	11	(	(	PUNCT
admet-1586	145	12	20:80	20:80	NUM
admet-1586	145	13	)	)	PUNCT
admet-1586	145	14	and	and	CCONJ
admet-1586	145	15	imc	imc	PROPN
admet-1586	145	16	-	-	PUNCT
admet-1586	145	17	mx	mx	PROPN
admet-1586	145	18	(	(	PUNCT
admet-1586	145	19	20:80	20:80	NUM
admet-1586	145	20	)	)	PUNCT
admet-1586	145	21	processed	process	VERB
admet-1586	145	22	at	at	ADP
admet-1586	145	23	170	170	NUM
admet-1586	145	24	°	°	NOUN
admet-1586	145	25	c	c	NOUN
admet-1586	145	26	showed	show	VERB
admet-1586	145	27	homogeneous	homogeneous	ADJ
admet-1586	145	28	distribution	distribution	NOUN
admet-1586	145	29	without	without	ADP
admet-1586	145	30	crystalline	crystalline	PROPN
admet-1586	145	31	imc	imc	PROPN
admet-1586	145	32	,	,	PUNCT
admet-1586	145	33	suggesting	suggest	VERB
admet-1586	145	34	that	that	SCONJ
admet-1586	145	35	imc	imc	PROPN
admet-1586	145	36	-	-	PUNCT
admet-1586	145	37	mg	mg	PROPN
admet-1586	145	38	(	(	PUNCT
admet-1586	145	39	20:80	20:80	NUM
admet-1586	145	40	)	)	PUNCT
admet-1586	145	41	also	also	ADV
admet-1586	145	42	formed	form	VERB
admet-1586	145	43	amorphous	amorphous	ADJ
admet-1586	145	44	dispersion	dispersion	NOUN
admet-1586	145	45	.	.	PUNCT
admet-1586	146	1	figure	figure	VERB
admet-1586	146	2	3c	3c	NUM
admet-1586	146	3	shows	show	VERB
admet-1586	146	4	the	the	DET
admet-1586	146	5	raman	raman	ADJ
admet-1586	146	6	spectra	spectra	NOUN
admet-1586	146	7	of	of	ADP
admet-1586	146	8	points	point	NOUN
admet-1586	146	9	a	a	DET
admet-1586	146	10	,	,	PUNCT
admet-1586	146	11	b	b	NOUN
admet-1586	146	12	,	,	PUNCT
admet-1586	146	13	c	c	NOUN
admet-1586	146	14	,	,	PUNCT
admet-1586	146	15	and	and	CCONJ
admet-1586	146	16	d	d	NOUN
admet-1586	146	17	,	,	PUNCT
admet-1586	146	18	highlighted	highlight	VERB
admet-1586	146	19	in	in	ADP
admet-1586	146	20	figure	figure	NOUN
admet-1586	146	21	3a	3a	NUM
admet-1586	146	22	.	.	PUNCT
admet-1586	147	1	points	points	PROPN
admet-1586	147	2	b	b	NUM
admet-1586	147	3	,	,	PUNCT
admet-1586	147	4	c	c	NOUN
admet-1586	147	5	,	,	PUNCT
admet-1586	147	6	and	and	CCONJ
admet-1586	147	7	d	d	X
admet-1586	147	8	highlight	highlight	VERB
admet-1586	147	9	the	the	DET
admet-1586	147	10	amorphous	amorphous	ADJ
admet-1586	147	11	pattern	pattern	NOUN
admet-1586	147	12	similar	similar	ADJ
admet-1586	147	13	to	to	ADP
admet-1586	147	14	the	the	DET
admet-1586	147	15	previous	previous	ADJ
admet-1586	147	16	study	study	NOUN
admet-1586	147	17	[	[	X
admet-1586	147	18	19	19	NUM
admet-1586	147	19	]	]	PUNCT
admet-1586	147	20	.	.	PUNCT
admet-1586	148	1	however	however	ADV
admet-1586	148	2	,	,	PUNCT
admet-1586	148	3	the	the	DET
admet-1586	148	4	crystalline	crystalline	ADJ
admet-1586	148	5	peak	peak	NOUN
admet-1586	148	6	of	of	ADP
admet-1586	148	7	imc	imc	NOUN
admet-1586	148	8	at	at	ADP
admet-1586	148	9	1700	1700	NUM
admet-1586	148	10	cm-1	cm-1	PART
admet-1586	149	1	[	[	X
admet-1586	149	2	31	31	NUM
admet-1586	149	3	]	]	PUNCT
admet-1586	149	4	appeared	appear	VERB
admet-1586	149	5	on	on	ADP
admet-1586	149	6	point	point	NOUN
admet-1586	149	7	b	b	NOUN
admet-1586	149	8	,	,	PUNCT
admet-1586	149	9	corresponding	correspond	VERB
admet-1586	149	10	to	to	ADP
admet-1586	149	11	a	a	DET
admet-1586	149	12	dark	dark	ADJ
admet-1586	149	13	gray	gray	ADJ
admet-1586	149	14	particle	particle	NOUN
admet-1586	149	15	in	in	ADP
admet-1586	149	16	imc	imc	PROPN
admet-1586	149	17	-	-	PUNCT
admet-1586	149	18	mg	mg	PROPN
admet-1586	149	19	(	(	PUNCT
admet-1586	149	20	20:80	20:80	NUM
admet-1586	149	21	)	)	PUNCT
admet-1586	149	22	at	at	ADP
admet-1586	149	23	120	120	NUM
admet-1586	149	24	°	°	NOUN
admet-1586	149	25	c	c	NOUN
admet-1586	149	26	.	.	PUNCT
admet-1586	150	1	it	it	PRON
admet-1586	150	2	appears	appear	VERB
admet-1586	150	3	that	that	SCONJ
admet-1586	150	4	the	the	DET
admet-1586	150	5	raman	raman	NOUN
admet-1586	150	6	image	image	NOUN
admet-1586	150	7	reflects	reflect	VERB
admet-1586	150	8	the	the	DET
admet-1586	150	9	distribution	distribution	NOUN
admet-1586	150	10	of	of	ADP
admet-1586	150	11	crystalline	crystalline	PROPN
admet-1586	150	12	imc	imc	PROPN
admet-1586	150	13	.	.	PUNCT
admet-1586	151	1	to	to	PART
admet-1586	151	2	compare	compare	VERB
admet-1586	151	3	the	the	DET
admet-1586	151	4	performance	performance	NOUN
admet-1586	151	5	of	of	ADP
admet-1586	151	6	the	the	DET
admet-1586	151	7	solid	solid	ADJ
admet-1586	151	8	dispersion	dispersion	NOUN
admet-1586	151	9	comprising	comprise	VERB
admet-1586	151	10	hpmc	hpmc	ADJ
admet-1586	151	11	-	-	PUNCT
admet-1586	151	12	mg	mg	ADJ
admet-1586	151	13	or	or	CCONJ
admet-1586	151	14	hpmc	hpmc	ADJ
admet-1586	151	15	-	-	PUNCT
admet-1586	151	16	mx	mx	PROPN
admet-1586	151	17	,	,	PUNCT
admet-1586	151	18	the	the	DET
admet-1586	151	19	solid	solid	ADJ
admet-1586	151	20	dispersion	dispersion	NOUN
admet-1586	151	21	prepared	prepare	VERB
admet-1586	151	22	at	at	ADP
admet-1586	151	23	170	170	NUM
admet-1586	151	24	°	°	ADP
admet-1586	151	25	c	c	NOUN
admet-1586	151	26	under	under	ADP
admet-1586	151	27	the	the	DET
admet-1586	151	28	same	same	ADJ
admet-1586	151	29	conditions	condition	NOUN
admet-1586	151	30	were	be	AUX
admet-1586	151	31	subjected	subject	VERB
admet-1586	151	32	to	to	ADP
admet-1586	151	33	further	further	ADJ
admet-1586	151	34	study	study	NOUN
admet-1586	151	35	.	.	PUNCT
admet-1586	152	1	preparation	preparation	NOUN
admet-1586	152	2	of	of	ADP
admet-1586	152	3	the	the	DET
admet-1586	152	4	powder	powder	NOUN
admet-1586	152	5	and	and	CCONJ
admet-1586	152	6	physical	physical	ADJ
admet-1586	152	7	stability	stability	NOUN
admet-1586	152	8	test	test	VERB
admet-1586	152	9	the	the	DET
admet-1586	152	10	solid	solid	ADJ
admet-1586	152	11	dispersion	dispersion	NOUN
admet-1586	152	12	powder	powder	NOUN
admet-1586	152	13	was	be	AUX
admet-1586	152	14	prepared	prepare	VERB
admet-1586	152	15	by	by	ADP
admet-1586	152	16	milling	mill	VERB
admet-1586	152	17	the	the	DET
admet-1586	152	18	hot	hot	ADJ
admet-1586	152	19	-	-	PUNCT
admet-1586	152	20	melt	melt	NOUN
admet-1586	152	21	extrude	extrude	NOUN
admet-1586	152	22	for	for	ADP
admet-1586	152	23	further	further	ADJ
admet-1586	152	24	experiments	experiment	NOUN
admet-1586	152	25	.	.	PUNCT
admet-1586	153	1	figure	figure	NOUN
admet-1586	153	2	4a	4a	NOUN
admet-1586	153	3	and	and	CCONJ
admet-1586	153	4	b	b	NOUN
admet-1586	153	5	show	show	VERB
admet-1586	153	6	the	the	DET
admet-1586	153	7	sem	sem	NOUN
admet-1586	153	8	images	image	NOUN
admet-1586	153	9	of	of	ADP
admet-1586	153	10	imc	imc	PROPN
admet-1586	153	11	-	-	PUNCT
admet-1586	153	12	mg	mg	PROPN
admet-1586	153	13	(	(	PUNCT
admet-1586	153	14	20:80	20:80	NUM
admet-1586	153	15	)	)	PUNCT
admet-1586	153	16	and	and	CCONJ
admet-1586	153	17	imc	imc	PROPN
admet-1586	153	18	-	-	PUNCT
admet-1586	153	19	mx	mx	PROPN
admet-1586	153	20	(	(	PUNCT
admet-1586	153	21	20:80	20:80	NUM
admet-1586	153	22	)	)	PUNCT
admet-1586	153	23	prepared	prepare	VERB
admet-1586	153	24	by	by	ADP
admet-1586	153	25	hot	hot	ADJ
admet-1586	153	26	-	-	PUNCT
admet-1586	153	27	melt	melt	NOUN
admet-1586	153	28	extrusion	extrusion	NOUN
admet-1586	153	29	at	at	ADP
admet-1586	153	30	170	170	NUM
admet-1586	153	31	°	°	NOUN
admet-1586	153	32	c	c	NOUN
admet-1586	153	33	followed	follow	VERB
admet-1586	153	34	by	by	ADP
admet-1586	153	35	milling	mill	VERB
admet-1586	153	36	.	.	PUNCT
admet-1586	154	1	a	a	DET
admet-1586	154	2	similar	similar	ADJ
admet-1586	154	3	particle	particle	NOUN
admet-1586	154	4	shape	shape	NOUN
admet-1586	154	5	and	and	CCONJ
admet-1586	154	6	size	size	NOUN
admet-1586	154	7	with	with	ADP
admet-1586	154	8	consolidated	consolidated	ADJ
admet-1586	154	9	and	and	CCONJ
admet-1586	154	10	smooth	smooth	ADJ
admet-1586	154	11	glass	glass	NOUN
admet-1586	154	12	-	-	PUNCT
admet-1586	154	13	like	like	ADJ
admet-1586	154	14	material	material	NOUN
admet-1586	154	15	can	can	AUX
admet-1586	154	16	be	be	AUX
admet-1586	154	17	seen	see	VERB
admet-1586	154	18	in	in	ADP
admet-1586	154	19	both	both	DET
admet-1586	154	20	images	image	NOUN
admet-1586	154	21	.	.	PUNCT
admet-1586	155	1	this	this	DET
admet-1586	155	2	appearance	appearance	NOUN
admet-1586	155	3	was	be	AUX
admet-1586	155	4	almost	almost	ADV
admet-1586	155	5	consistent	consistent	ADJ
admet-1586	155	6	with	with	ADP
admet-1586	155	7	a	a	DET
admet-1586	155	8	previous	previous	ADJ
admet-1586	155	9	study	study	NOUN
admet-1586	155	10	[	[	X
admet-1586	155	11	32	32	NUM
admet-1586	155	12	]	]	PUNCT
admet-1586	155	13	.	.	PUNCT
admet-1586	156	1	(	(	PUNCT
admet-1586	156	2	a	a	X
admet-1586	156	3	)	)	PUNCT
admet-1586	156	4	(	(	PUNCT
admet-1586	156	5	b	b	X
admet-1586	156	6	)	)	PUNCT
admet-1586	156	7	figure	figure	NOUN
admet-1586	156	8	4	4	NUM
admet-1586	156	9	.	.	PUNCT
admet-1586	156	10	sem	sem	NOUN
admet-1586	156	11	images	image	NOUN
admet-1586	156	12	of	of	ADP
admet-1586	156	13	hot	hot	ADJ
admet-1586	156	14	-	-	PUNCT
admet-1586	156	15	melt	melt	NOUN
admet-1586	156	16	extruded	extrude	VERB
admet-1586	156	17	at	at	ADP
admet-1586	156	18	170	170	NUM
admet-1586	156	19	°	°	ADP
admet-1586	156	20	c	c	NOUN
admet-1586	156	21	after	after	ADP
admet-1586	156	22	milling	mill	VERB
admet-1586	156	23	for	for	ADP
admet-1586	156	24	(	(	PUNCT
admet-1586	156	25	a	a	PRON
admet-1586	156	26	)	)	PUNCT
admet-1586	156	27	imc	imc	PROPN
admet-1586	156	28	-	-	PUNCT
admet-1586	156	29	mg	mg	PROPN
admet-1586	156	30	(	(	PUNCT
admet-1586	156	31	20:80	20:80	NUM
admet-1586	156	32	)	)	PUNCT
admet-1586	156	33	and	and	CCONJ
admet-1586	156	34	(	(	PUNCT
admet-1586	156	35	b	b	NOUN
admet-1586	156	36	)	)	PUNCT
admet-1586	156	37	imc	imc	PROPN
admet-1586	156	38	-	-	PUNCT
admet-1586	156	39	mx	mx	PROPN
admet-1586	156	40	(	(	PUNCT
admet-1586	156	41	20:80	20:80	NUM
admet-1586	156	42	)	)	PUNCT
admet-1586	156	43	.	.	PUNCT
admet-1586	157	1	figure	figure	NOUN
admet-1586	157	2	5	5	NUM
admet-1586	157	3	shows	show	VERB
admet-1586	157	4	the	the	DET
admet-1586	157	5	xrpd	xrpd	PROPN
admet-1586	157	6	patterns	pattern	NOUN
admet-1586	157	7	of	of	ADP
admet-1586	157	8	imc	imc	PROPN
admet-1586	157	9	-	-	PUNCT
admet-1586	157	10	mg	mg	PROPN
admet-1586	157	11	(	(	PUNCT
admet-1586	157	12	20:80	20:80	NUM
admet-1586	157	13	)	)	PUNCT
admet-1586	157	14	and	and	CCONJ
admet-1586	157	15	imc	imc	PROPN
admet-1586	157	16	-	-	PUNCT
admet-1586	157	17	mx	mx	PROPN
admet-1586	157	18	(	(	PUNCT
admet-1586	157	19	20:80	20:80	NUM
admet-1586	157	20	)	)	PUNCT
admet-1586	157	21	prepared	prepare	VERB
admet-1586	157	22	by	by	ADP
admet-1586	157	23	hot	hot	ADJ
admet-1586	157	24	-	-	PUNCT
admet-1586	157	25	melt	melt	NOUN
admet-1586	157	26	extrusion	extrusion	NOUN
admet-1586	157	27	at	at	ADP
admet-1586	157	28	170	170	NUM
admet-1586	157	29	°	°	NOUN
admet-1586	157	30	c	c	NOUN
admet-1586	157	31	followed	follow	VERB
admet-1586	157	32	by	by	ADP
admet-1586	157	33	milling	mill	VERB
admet-1586	157	34	.	.	PUNCT
admet-1586	158	1	all	all	DET
admet-1586	158	2	samples	sample	NOUN
admet-1586	158	3	showed	show	VERB
admet-1586	158	4	no	no	DET
admet-1586	158	5	x	x	NOUN
admet-1586	158	6	-	-	NOUN
admet-1586	158	7	ray	ray	NOUN
admet-1586	158	8	diffraction	diffraction	NOUN
admet-1586	158	9	peak	peak	NOUN
admet-1586	158	10	derived	derive	VERB
admet-1586	158	11	from	from	ADP
admet-1586	158	12	imc	imc	PROPN
admet-1586	158	13	,	,	PUNCT
admet-1586	158	14	suggesting	suggest	VERB
admet-1586	158	15	amorphization	amorphization	NOUN
admet-1586	158	16	was	be	AUX
admet-1586	158	17	achieved	achieve	VERB
admet-1586	158	18	following	follow	VERB
admet-1586	158	19	the	the	DET
admet-1586	158	20	process	process	NOUN
admet-1586	158	21	.	.	PUNCT
admet-1586	159	1	furthermore	furthermore	ADV
admet-1586	159	2	,	,	PUNCT
admet-1586	159	3	they	they	PRON
admet-1586	159	4	were	be	AUX
admet-1586	159	5	physically	physically	ADV
admet-1586	159	6	stable	stable	ADJ
admet-1586	159	7	;	;	PUNCT
admet-1586	159	8	no	no	DET
admet-1586	159	9	crystallization	crystallization	NOUN
admet-1586	159	10	occurred	occur	VERB
admet-1586	159	11	,	,	PUNCT
admet-1586	159	12	and	and	CCONJ
admet-1586	159	13	the	the	DET
admet-1586	159	14	amorphous	amorphous	ADJ
admet-1586	159	15	form	form	NOUN
admet-1586	159	16	was	be	AUX
admet-1586	159	17	stored	store	VERB
admet-1586	159	18	for	for	ADP
admet-1586	159	19	three	three	NUM
admet-1586	159	20	months	month	NOUN
admet-1586	159	21	at	at	ADP
admet-1586	159	22	40	40	NUM
admet-1586	159	23	°	°	NOUN
admet-1586	159	24	c	c	NOUN
admet-1586	159	25	.	.	PUNCT
admet-1586	160	1	it	it	PRON
admet-1586	160	2	is	be	AUX
admet-1586	160	3	commonly	commonly	ADV
admet-1586	160	4	known	know	VERB
admet-1586	160	5	that	that	SCONJ
admet-1586	160	6	tg	tg	PROPN
admet-1586	160	7	is	be	AUX
admet-1586	160	8	a	a	DET
admet-1586	160	9	key	key	ADJ
admet-1586	160	10	parameter	parameter	NOUN
admet-1586	160	11	used	use	VERB
admet-1586	160	12	to	to	PART
admet-1586	160	13	determine	determine	VERB
admet-1586	160	14	the	the	DET
admet-1586	160	15	crystallization	crystallization	NOUN
admet-1586	160	16	tendency	tendency	NOUN
admet-1586	160	17	of	of	ADP
admet-1586	160	18	amorphous	amorphous	ADJ
admet-1586	160	19	compounds	compound	NOUN
admet-1586	160	20	because	because	SCONJ
admet-1586	160	21	the	the	DET
admet-1586	160	22	molecular	molecular	ADJ
admet-1586	160	23	mobility	mobility	NOUN
admet-1586	160	24	is	be	AUX
admet-1586	160	25	significantly	significantly	ADV
admet-1586	160	26	elevated	elevate	VERB
admet-1586	160	27	over	over	ADP
admet-1586	160	28	tg	tg	PROPN
admet-1586	160	29	with	with	ADP
admet-1586	160	30	glass	glass	NOUN
admet-1586	160	31	transition	transition	NOUN
admet-1586	161	1	[	[	X
admet-1586	161	2	33,34	33,34	NOUN
admet-1586	161	3	]	]	PUNCT
admet-1586	161	4	.	.	PUNCT
admet-1586	162	1	in	in	ADP
admet-1586	162	2	addition	addition	NOUN
admet-1586	162	3	,	,	PUNCT
admet-1586	162	4	the	the	DET
admet-1586	162	5	formation	formation	NOUN
admet-1586	162	6	of	of	ADP
admet-1586	162	7	intermolecular	intermolecular	ADJ
admet-1586	162	8	interaction	interaction	NOUN
admet-1586	162	9	between	between	ADP
admet-1586	162	10	the	the	DET
admet-1586	162	11	drug	drug	NOUN
admet-1586	162	12	and	and	CCONJ
admet-1586	162	13	polymeric	polymeric	ADJ
admet-1586	162	14	carrier	carrier	NOUN
admet-1586	162	15	has	have	AUX
admet-1586	162	16	been	be	AUX
admet-1586	162	17	reported	report	VERB
admet-1586	162	18	to	to	PART
admet-1586	162	19	play	play	VERB
admet-1586	162	20	an	an	DET
admet-1586	162	21	important	important	ADJ
admet-1586	162	22	role	role	NOUN
admet-1586	162	23	in	in	ADP
admet-1586	162	24	maintaining	maintain	VERB
admet-1586	162	25	an	an	DET
admet-1586	162	26	amorphous	amorphous	ADJ
admet-1586	162	27	state	state	NOUN
admet-1586	163	1	[	[	X
admet-1586	163	2	12,15	12,15	NUM
admet-1586	163	3	]	]	X
admet-1586	163	4	.	.	PUNCT
admet-1586	164	1	solid	solid	ADJ
admet-1586	164	2	dispersion	dispersion	NOUN
admet-1586	164	3	comprising	comprising	NOUN
admet-1586	164	4	of	of	ADP
admet-1586	164	5	>	>	PUNCT
admet-1586	164	6	60	60	NUM
admet-1586	164	7	%	%	NOUN
admet-1586	164	8	of	of	ADP
admet-1586	164	9	hpmcas	hpmca	NOUN
admet-1586	164	10	-	-	PUNCT
admet-1586	164	11	mg	mg	PROPN
admet-1586	164	12	or	or	CCONJ
admet-1586	164	13	hpmcas	hpmca	NOUN
admet-1586	164	14	-	-	PUNCT
admet-1586	164	15	mx	mx	NOUN
admet-1586	164	16	showed	show	VERB
admet-1586	164	17	a	a	DET
admet-1586	164	18	tg	tg	NOUN
admet-1586	164	19	over	over	ADP
admet-1586	164	20	70	70	NUM
admet-1586	164	21	°	°	NOUN
admet-1586	164	22	c	c	NOUN
admet-1586	164	23	;	;	PUNCT
admet-1586	164	24	the	the	DET
admet-1586	164	25	formation	formation	NOUN
admet-1586	164	26	of	of	ADP
admet-1586	164	27	intermolecular	intermolecular	ADJ
admet-1586	164	28	interaction	interaction	NOUN
admet-1586	164	29	between	between	ADP
admet-1586	164	30	imc	imc	PROPN
admet-1586	164	31	and	and	CCONJ
admet-1586	164	32	hpmcasmg	hpmcasmg	PROPN
admet-1586	164	33	/	/	SYM
admet-1586	164	34	hpmcas	hpmca	NOUN
admet-1586	164	35	-	-	PUNCT
admet-1586	164	36	mx	mx	PROPN
admet-1586	164	37	was	be	AUX
admet-1586	164	38	characterized	characterize	VERB
admet-1586	164	39	by	by	ADP
admet-1586	164	40	a	a	DET
admet-1586	164	41	change	change	NOUN
admet-1586	164	42	in	in	ADP
admet-1586	164	43	infrared	infrared	ADJ
admet-1586	164	44	spectra	spectra	NOUN
admet-1586	164	45	[	[	X
admet-1586	164	46	19	19	NUM
admet-1586	164	47	]	]	PUNCT
admet-1586	164	48	.	.	PUNCT
admet-1586	165	1	the	the	DET
admet-1586	165	2	difference	difference	NOUN
admet-1586	165	3	between	between	ADP
admet-1586	165	4	the	the	DET
admet-1586	165	5	tg	tg	PROPN
admet-1586	165	6	and	and	CCONJ
admet-1586	165	7	imc	imc	PROPN
admet-1586	165	8	-	-	PUNCT
admet-1586	165	9	mg	mg	PROPN
admet-1586	165	10	(	(	PUNCT
admet-1586	165	11	20:80	20:80	NUM
admet-1586	165	12	)	)	PUNCT
admet-1586	165	13	imc	imc	PROPN
admet-1586	165	14	-	-	PUNCT
admet-1586	165	15	mx	mx	PROPN
admet-1586	165	16	(	(	PUNCT
admet-1586	165	17	20:80	20:80	NUM
admet-1586	165	18	)	)	PUNCT
admet-1586	165	19	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	NOUN
admet-1586	165	20	h.	h.	PROPN
admet-1586	165	21	tanaka	tanaka	PROPN
admet-1586	165	22	et	et	PROPN
admet-1586	165	23	al	al	PROPN
admet-1586	165	24	.	.	PROPN
admet-1586	165	25	admet	admet	PROPN
admet-1586	165	26	&	&	CCONJ
admet-1586	165	27	dmpk	dmpk	PROPN
admet-1586	165	28	11(3	11(3	NUM
admet-1586	165	29	)	)	PUNCT
admet-1586	165	30	(	(	PUNCT
admet-1586	165	31	2023	2023	NUM
admet-1586	165	32	)	)	PUNCT
admet-1586	165	33	373	373	NUM
admet-1586	165	34	-	-	SYM
admet-1586	165	35	385	385	NUM
admet-1586	165	36	380	380	NUM
admet-1586	165	37	storage	storage	NOUN
admet-1586	165	38	temperature	temperature	NOUN
admet-1586	165	39	and	and	CCONJ
admet-1586	165	40	the	the	DET
admet-1586	165	41	formation	formation	NOUN
admet-1586	165	42	of	of	ADP
admet-1586	165	43	intermolecular	intermolecular	ADJ
admet-1586	165	44	interaction	interaction	NOUN
admet-1586	165	45	with	with	ADP
admet-1586	165	46	hpmcas	hpmca	NOUN
admet-1586	165	47	-	-	PUNCT
admet-1586	165	48	mg	mg	PROPN
admet-1586	165	49	or	or	CCONJ
admet-1586	165	50	hpmcas	hpmca	NOUN
admet-1586	165	51	-	-	PUNCT
admet-1586	165	52	mx	mx	NOUN
admet-1586	165	53	should	should	AUX
admet-1586	165	54	result	result	VERB
admet-1586	165	55	in	in	ADP
admet-1586	165	56	higher	high	ADJ
admet-1586	165	57	physical	physical	ADJ
admet-1586	165	58	stability	stability	NOUN
admet-1586	165	59	.	.	PUNCT
admet-1586	166	1	2	2	NUM
admet-1586	166	2	/	/	SYM
admet-1586	167	1	°	°	NUM
admet-1586	167	2	figure	figure	NOUN
admet-1586	167	3	5	5	NUM
admet-1586	167	4	.	.	PUNCT
admet-1586	168	1	xrpd	xrpd	ADJ
admet-1586	168	2	patterns	pattern	NOUN
admet-1586	168	3	of	of	ADP
admet-1586	168	4	hot	hot	ADJ
admet-1586	168	5	-	-	PUNCT
admet-1586	168	6	melt	melt	NOUN
admet-1586	168	7	extruded	extrude	VERB
admet-1586	168	8	at	at	ADP
admet-1586	168	9	170	170	NUM
admet-1586	168	10	°	°	ADP
admet-1586	168	11	c	c	NOUN
admet-1586	168	12	after	after	ADP
admet-1586	168	13	milling	mill	VERB
admet-1586	168	14	for	for	ADP
admet-1586	168	15	imc	imc	PROPN
admet-1586	168	16	-	-	PUNCT
admet-1586	168	17	mg	mg	PROPN
admet-1586	168	18	(	(	PUNCT
admet-1586	168	19	20:80	20:80	NUM
admet-1586	168	20	)	)	PUNCT
admet-1586	168	21	and	and	CCONJ
admet-1586	168	22	imc	imc	PROPN
admet-1586	168	23	-	-	PUNCT
admet-1586	168	24	mx	mx	PROPN
admet-1586	168	25	(	(	PUNCT
admet-1586	168	26	20:80	20:80	NUM
admet-1586	168	27	)	)	PUNCT
admet-1586	168	28	before	before	ADP
admet-1586	168	29	and	and	CCONJ
admet-1586	168	30	three	three	NUM
admet-1586	168	31	months	month	NOUN
admet-1586	168	32	after	after	ADP
admet-1586	168	33	storage	storage	NOUN
admet-1586	168	34	at	at	ADP
admet-1586	168	35	40	40	NUM
admet-1586	168	36	°	°	NOUN
admet-1586	168	37	c	c	NOUN
admet-1586	168	38	.	.	PUNCT
admet-1586	168	39	dissolution	dissolution	NOUN
admet-1586	168	40	-	-	PUNCT
admet-1586	168	41	permeation	permeation	NOUN
admet-1586	168	42	test	test	NOUN
admet-1586	168	43	dissolution	dissolution	NOUN
admet-1586	168	44	and	and	CCONJ
admet-1586	168	45	the	the	DET
admet-1586	168	46	subsequent	subsequent	ADJ
admet-1586	168	47	permeation	permeation	NOUN
admet-1586	168	48	profiles	profile	NOUN
admet-1586	168	49	of	of	ADP
admet-1586	168	50	crystalline	crystalline	PROPN
admet-1586	168	51	imc	imc	PROPN
admet-1586	168	52	and	and	CCONJ
admet-1586	168	53	the	the	DET
admet-1586	168	54	solid	solid	ADJ
admet-1586	168	55	dispersions	dispersion	NOUN
admet-1586	168	56	were	be	AUX
admet-1586	168	57	studied	study	VERB
admet-1586	168	58	with	with	ADP
admet-1586	168	59	simultaneous	simultaneous	ADJ
admet-1586	168	60	measurement	measurement	NOUN
admet-1586	168	61	for	for	ADP
admet-1586	168	62	donor	donor	NOUN
admet-1586	168	63	-	-	PUNCT
admet-1586	168	64	acceptor	acceptor	NOUN
admet-1586	168	65	chambers	chamber	NOUN
admet-1586	168	66	using	use	VERB
admet-1586	168	67	a	a	DET
admet-1586	168	68	microflux	microflux	NOUN
admet-1586	168	69	™	™	NOUN
admet-1586	168	70	.	.	PUNCT
admet-1586	169	1	figure	figure	VERB
admet-1586	169	2	6a	6a	NOUN
admet-1586	169	3	shows	show	VERB
admet-1586	169	4	the	the	DET
admet-1586	169	5	dissolution	dissolution	ADJ
admet-1586	169	6	profiles	profile	NOUN
admet-1586	169	7	of	of	ADP
admet-1586	169	8	crystalline	crystalline	PROPN
admet-1586	169	9	imc	imc	PROPN
admet-1586	169	10	and	and	CCONJ
admet-1586	169	11	the	the	DET
admet-1586	169	12	solid	solid	ADJ
admet-1586	169	13	dispersions	dispersion	NOUN
admet-1586	169	14	of	of	ADP
admet-1586	169	15	imc	imc	PROPN
admet-1586	169	16	-	-	PUNCT
admet-1586	169	17	mg	mg	PROPN
admet-1586	169	18	(	(	PUNCT
admet-1586	169	19	20:80	20:80	NUM
admet-1586	169	20	)	)	PUNCT
admet-1586	169	21	and	and	CCONJ
admet-1586	169	22	imc	imc	PROPN
admet-1586	169	23	-	-	PUNCT
admet-1586	169	24	mx	mx	PROPN
admet-1586	169	25	(	(	PUNCT
admet-1586	169	26	20:80	20:80	NUM
admet-1586	169	27	)	)	PUNCT
admet-1586	169	28	prepared	prepare	VERB
admet-1586	169	29	by	by	ADP
admet-1586	169	30	hot	hot	ADJ
admet-1586	169	31	-	-	PUNCT
admet-1586	169	32	melt	melt	NOUN
admet-1586	169	33	extrusion	extrusion	NOUN
admet-1586	169	34	at	at	ADP
admet-1586	169	35	170	170	NUM
admet-1586	169	36	°	°	NOUN
admet-1586	169	37	c	c	NOUN
admet-1586	169	38	.	.	PUNCT
admet-1586	170	1	the	the	DET
admet-1586	170	2	concentration	concentration	NOUN
admet-1586	170	3	of	of	ADP
admet-1586	170	4	crystalline	crystalline	NOUN
admet-1586	170	5	imc	imc	PROPN
admet-1586	170	6	in	in	ADP
admet-1586	170	7	the	the	DET
admet-1586	170	8	dissolution	dissolution	NOUN
admet-1586	170	9	medium	medium	NOUN
admet-1586	170	10	increased	increase	VERB
admet-1586	170	11	time	time	NOUN
admet-1586	170	12	-	-	PUNCT
admet-1586	170	13	dependently	dependently	ADV
admet-1586	170	14	and	and	CCONJ
admet-1586	170	15	almost	almost	ADV
admet-1586	170	16	achieved	achieve	VERB
admet-1586	170	17	a	a	DET
admet-1586	170	18	plateau	plateau	NOUN
admet-1586	170	19	at	at	ADP
admet-1586	170	20	185.9	185.9	NUM
admet-1586	170	21			PROPN
admet-1586	170	22	0.9	0.9	NUM
admet-1586	170	23	µg	µg	ADV
admet-1586	170	24	ml-1	ml-1	ADV
admet-1586	170	25	between	between	ADP
admet-1586	170	26	420	420	NUM
admet-1586	170	27	and	and	CCONJ
admet-1586	170	28	480	480	NUM
admet-1586	170	29	min	min	NOUN
admet-1586	170	30	.	.	PROPN
admet-1586	171	1	this	this	DET
admet-1586	171	2	result	result	NOUN
admet-1586	171	3	was	be	AUX
admet-1586	171	4	similar	similar	ADJ
admet-1586	171	5	to	to	ADP
admet-1586	171	6	that	that	PRON
admet-1586	171	7	of	of	ADP
admet-1586	171	8	the	the	DET
admet-1586	171	9	solubility	solubility	NOUN
admet-1586	171	10	test	test	NOUN
admet-1586	171	11	;	;	PUNCT
admet-1586	171	12	the	the	DET
admet-1586	171	13	equilibrium	equilibrium	NOUN
admet-1586	171	14	solubility	solubility	NOUN
admet-1586	171	15	of	of	ADP
admet-1586	171	16	crystalline	crystalline	PROPN
admet-1586	171	17	imc	imc	PROPN
admet-1586	171	18	for	for	ADP
admet-1586	171	19	the	the	DET
admet-1586	171	20	acceptor	acceptor	NOUN
admet-1586	171	21	medium	medium	NOUN
admet-1586	171	22	was	be	AUX
admet-1586	171	23	177.22.7	177.22.7	NUM
admet-1586	171	24	µg	µg	ADV
admet-1586	171	25	ml-1	ml-1	NUM
admet-1586	171	26	,	,	PUNCT
admet-1586	171	27	which	which	PRON
admet-1586	171	28	was	be	AUX
admet-1586	171	29	also	also	ADV
admet-1586	171	30	similar	similar	ADJ
admet-1586	171	31	to	to	ADP
admet-1586	171	32	the	the	DET
admet-1586	171	33	previously	previously	ADV
admet-1586	171	34	reported	report	VERB
admet-1586	171	35	value	value	NOUN
admet-1586	171	36	(	(	PUNCT
admet-1586	171	37	approximately	approximately	ADV
admet-1586	171	38	200	200	NUM
admet-1586	171	39	µg	µg	ADV
admet-1586	171	40	ml-1	ml-1	X
admet-1586	171	41	)	)	PUNCT
admet-1586	172	1	[	[	X
admet-1586	172	2	35	35	NUM
admet-1586	172	3	]	]	PUNCT
admet-1586	172	4	.	.	PUNCT
admet-1586	173	1	the	the	DET
admet-1586	173	2	dissolution	dissolution	ADJ
admet-1586	173	3	profile	profile	NOUN
admet-1586	173	4	of	of	ADP
admet-1586	173	5	imc	imc	PROPN
admet-1586	173	6	was	be	AUX
admet-1586	173	7	significantly	significantly	ADV
admet-1586	173	8	improved	improve	VERB
admet-1586	173	9	by	by	ADP
admet-1586	173	10	formulation	formulation	NOUN
admet-1586	173	11	of	of	ADP
admet-1586	173	12	the	the	DET
admet-1586	173	13	solid	solid	ADJ
admet-1586	173	14	dispersion	dispersion	NOUN
admet-1586	173	15	.	.	PUNCT
admet-1586	174	1	the	the	DET
admet-1586	174	2	initial	initial	ADJ
admet-1586	174	3	dissolution	dissolution	NOUN
admet-1586	174	4	rate	rate	NOUN
admet-1586	174	5	and	and	CCONJ
admet-1586	174	6	dissolved	dissolve	VERB
admet-1586	174	7	amount	amount	NOUN
admet-1586	174	8	of	of	ADP
admet-1586	174	9	imc	imc	PROPN
admet-1586	174	10	elevated	elevate	VERB
admet-1586	174	11	to	to	ADP
admet-1586	174	12	around	around	ADP
admet-1586	174	13	3080.4	3080.4	NUM
admet-1586	174	14	and	and	CCONJ
admet-1586	174	15	3160.5	3160.5	NUM
admet-1586	174	16	µg	µg	ADV
admet-1586	174	17	ml-1	ml-1	PRON
admet-1586	174	18	between	between	ADP
admet-1586	174	19	420	420	NUM
admet-1586	174	20	-	-	SYM
admet-1586	174	21	480	480	NUM
admet-1586	174	22	min	min	NOUN
admet-1586	174	23	for	for	ADP
admet-1586	174	24	both	both	CCONJ
admet-1586	174	25	imc	imc	PROPN
admet-1586	174	26	-	-	PUNCT
admet-1586	174	27	mg	mg	PROPN
admet-1586	174	28	(	(	PUNCT
admet-1586	174	29	20:80	20:80	NUM
admet-1586	174	30	)	)	PUNCT
admet-1586	174	31	and	and	CCONJ
admet-1586	174	32	imc	imc	PROPN
admet-1586	174	33	-	-	PUNCT
admet-1586	174	34	mx	mx	PROPN
admet-1586	174	35	(	(	PUNCT
admet-1586	174	36	20:80	20:80	NUM
admet-1586	174	37	)	)	PUNCT
admet-1586	174	38	,	,	PUNCT
admet-1586	174	39	respectively	respectively	ADV
admet-1586	174	40	.	.	PUNCT
admet-1586	175	1	furthermore	furthermore	ADV
admet-1586	175	2	,	,	PUNCT
admet-1586	175	3	no	no	DET
admet-1586	175	4	precipitation	precipitation	NOUN
admet-1586	175	5	tendency	tendency	NOUN
admet-1586	175	6	was	be	AUX
admet-1586	175	7	observed	observe	VERB
admet-1586	175	8	for	for	ADP
admet-1586	175	9	both	both	CCONJ
admet-1586	175	10	the	the	DET
admet-1586	175	11	solid	solid	ADJ
admet-1586	175	12	dispersions	dispersion	NOUN
admet-1586	175	13	,	,	PUNCT
admet-1586	175	14	keeping	keep	VERB
admet-1586	175	15	supersaturation	supersaturation	NOUN
admet-1586	175	16	during	during	ADP
admet-1586	175	17	the	the	DET
admet-1586	175	18	test	test	NOUN
admet-1586	175	19	time	time	NOUN
admet-1586	175	20	.	.	PUNCT
admet-1586	176	1	these	these	DET
admet-1586	176	2	dissolved	dissolve	VERB
admet-1586	176	3	amounts	amount	NOUN
admet-1586	176	4	of	of	ADP
admet-1586	176	5	imc	imc	PROPN
admet-1586	176	6	were	be	AUX
admet-1586	176	7	similar	similar	ADJ
admet-1586	176	8	to	to	ADP
admet-1586	176	9	a	a	DET
admet-1586	176	10	previously	previously	ADV
admet-1586	176	11	reported	report	VERB
admet-1586	176	12	value	value	NOUN
admet-1586	176	13	of	of	ADP
admet-1586	176	14	a	a	DET
admet-1586	176	15	solid	solid	ADJ
admet-1586	176	16	dispersion	dispersion	NOUN
admet-1586	176	17	comprising	comprise	VERB
admet-1586	176	18	imc	imc	PROPN
admet-1586	176	19	and	and	CCONJ
admet-1586	176	20	hpmcas	hpmca	NOUN
admet-1586	176	21	-	-	PUNCT
admet-1586	176	22	lf	lf	NOUN
admet-1586	176	23	[	[	X
admet-1586	176	24	36	36	NUM
admet-1586	176	25	]	]	PUNCT
admet-1586	176	26	.	.	PUNCT
admet-1586	177	1	figure	figure	NOUN
admet-1586	177	2	6b	6b	PROPN
admet-1586	177	3	shows	show	VERB
admet-1586	177	4	the	the	DET
admet-1586	177	5	magnified	magnify	VERB
admet-1586	177	6	dissolution	dissolution	NOUN
admet-1586	177	7	profiles	profile	NOUN
admet-1586	177	8	within	within	ADP
admet-1586	177	9	2	2	NUM
admet-1586	177	10	min	min	NOUN
admet-1586	177	11	.	.	PUNCT
admet-1586	178	1	the	the	DET
admet-1586	178	2	slope	slope	NOUN
admet-1586	178	3	of	of	ADP
admet-1586	178	4	the	the	DET
admet-1586	178	5	concentration	concentration	NOUN
admet-1586	178	6	as	as	ADP
admet-1586	178	7	a	a	DET
admet-1586	178	8	function	function	NOUN
admet-1586	178	9	of	of	ADP
admet-1586	178	10	experimental	experimental	ADJ
admet-1586	178	11	time	time	NOUN
admet-1586	178	12	was	be	AUX
admet-1586	178	13	calculated	calculate	VERB
admet-1586	178	14	between	between	ADP
admet-1586	178	15	0	0	NUM
admet-1586	178	16	-	-	SYM
admet-1586	178	17	1	1	NUM
admet-1586	178	18	min	min	NOUN
admet-1586	178	19	for	for	ADP
admet-1586	178	20	the	the	DET
admet-1586	178	21	solid	solid	ADJ
admet-1586	178	22	dispersions	dispersion	NOUN
admet-1586	178	23	,	,	PUNCT
admet-1586	178	24	but	but	CCONJ
admet-1586	178	25	crystalline	crystalline	PROPN
admet-1586	178	26	imc	imc	PROPN
admet-1586	178	27	was	be	AUX
admet-1586	178	28	calculated	calculate	VERB
admet-1586	178	29	until	until	ADP
admet-1586	178	30	2	2	NUM
admet-1586	178	31	min	min	NOUN
admet-1586	178	32	because	because	SCONJ
admet-1586	178	33	the	the	DET
admet-1586	178	34	dissolution	dissolution	NOUN
admet-1586	178	35	was	be	AUX
admet-1586	178	36	significantly	significantly	ADV
admet-1586	178	37	low	low	ADJ
admet-1586	178	38	until	until	ADP
admet-1586	178	39	1	1	NUM
admet-1586	178	40	min	min	NOUN
admet-1586	178	41	.	.	PUNCT
admet-1586	179	1	the	the	DET
admet-1586	179	2	initial	initial	ADJ
admet-1586	179	3	dissolution	dissolution	NOUN
admet-1586	179	4	rate	rate	NOUN
admet-1586	179	5	represented	represent	VERB
admet-1586	179	6	as	as	ADP
admet-1586	179	7	the	the	DET
admet-1586	179	8	slope	slope	NOUN
admet-1586	179	9	of	of	ADP
admet-1586	179	10	crystalline	crystalline	PROPN
admet-1586	179	11	imc	imc	PROPN
admet-1586	179	12	was	be	AUX
admet-1586	179	13	1.6	1.6	NUM
admet-1586	179	14	(	(	PUNCT
admet-1586	179	15	µg	µg	ADV
admet-1586	179	16	ml-1	ml-1	X
admet-1586	179	17	)	)	PUNCT
admet-1586	179	18	min-1	min-1	NOUN
admet-1586	179	19	,	,	PUNCT
admet-1586	179	20	while	while	SCONJ
admet-1586	179	21	the	the	DET
admet-1586	179	22	solid	solid	ADJ
admet-1586	179	23	dispersion	dispersion	NOUN
admet-1586	179	24	of	of	ADP
admet-1586	179	25	imc	imc	PROPN
admet-1586	179	26	-	-	PUNCT
admet-1586	179	27	mg	mg	PROPN
admet-1586	179	28	(	(	PUNCT
admet-1586	179	29	20:80	20:80	NUM
admet-1586	179	30	)	)	PUNCT
admet-1586	179	31	and	and	CCONJ
admet-1586	179	32	imc	imc	PROPN
admet-1586	179	33	-	-	PUNCT
admet-1586	179	34	mx	mx	PROPN
admet-1586	179	35	(	(	PUNCT
admet-1586	179	36	20:80	20:80	NUM
admet-1586	179	37	)	)	PUNCT
admet-1586	179	38	were	be	AUX
admet-1586	179	39	46.0	46.0	NUM
admet-1586	179	40	and	and	CCONJ
admet-1586	179	41	44.3	44.3	NUM
admet-1586	179	42	(	(	PUNCT
admet-1586	179	43	µg	µg	ADV
admet-1586	179	44	ml-1	ml-1	X
admet-1586	179	45	)	)	PUNCT
admet-1586	179	46	min-1	min-1	NOUN
admet-1586	179	47	,	,	PUNCT
admet-1586	179	48	corresponding	correspond	VERB
admet-1586	179	49	to	to	ADP
admet-1586	179	50	about	about	ADP
admet-1586	179	51	a	a	DET
admet-1586	179	52	29and	29and	ADJ
admet-1586	179	53	28	28	NUM
admet-1586	179	54	-	-	ADJ
admet-1586	179	55	fold	fold	VERB
admet-1586	179	56	bigger	big	ADJ
admet-1586	179	57	improvement	improvement	NOUN
admet-1586	179	58	,	,	PUNCT
admet-1586	179	59	respectively	respectively	ADV
admet-1586	179	60	.	.	PUNCT
admet-1586	180	1	improvement	improvement	NOUN
admet-1586	180	2	of	of	ADP
admet-1586	180	3	the	the	DET
admet-1586	180	4	dissolution	dissolution	NOUN
admet-1586	180	5	rate	rate	NOUN
admet-1586	180	6	by	by	ADP
admet-1586	180	7	the	the	DET
admet-1586	180	8	formation	formation	NOUN
admet-1586	180	9	of	of	ADP
admet-1586	180	10	solid	solid	ADJ
admet-1586	180	11	dispersion	dispersion	NOUN
admet-1586	180	12	using	use	VERB
admet-1586	180	13	hpmcas	hpmca	NOUN
admet-1586	180	14	as	as	ADP
admet-1586	180	15	a	a	DET
admet-1586	180	16	polymeric	polymeric	ADJ
admet-1586	180	17	carrier	carrier	NOUN
admet-1586	180	18	has	have	AUX
admet-1586	180	19	been	be	AUX
admet-1586	180	20	investigated	investigate	VERB
admet-1586	180	21	for	for	ADP
admet-1586	180	22	various	various	ADJ
admet-1586	180	23	drugs	drug	NOUN
admet-1586	180	24	[	[	X
admet-1586	180	25	37	37	NUM
admet-1586	180	26	-	-	SYM
admet-1586	180	27	39	39	NUM
admet-1586	180	28	]	]	PUNCT
admet-1586	180	29	.	.	PUNCT
admet-1586	181	1	the	the	DET
admet-1586	181	2	formation	formation	NOUN
admet-1586	181	3	of	of	ADP
admet-1586	181	4	a	a	DET
admet-1586	181	5	drug	drug	NOUN
admet-1586	181	6	-	-	PUNCT
admet-1586	181	7	rich	rich	ADJ
admet-1586	181	8	phase	phase	NOUN
admet-1586	181	9	of	of	ADP
admet-1586	181	10	danazol	danazol	ADJ
admet-1586	181	11	under	under	ADP
admet-1586	181	12	a	a	DET
admet-1586	181	13	supersaturated	supersaturated	ADJ
admet-1586	181	14	state	state	NOUN
admet-1586	181	15	was	be	AUX
admet-1586	181	16	confirmed	confirm	VERB
admet-1586	181	17	prior	prior	ADV
admet-1586	181	18	to	to	ADP
admet-1586	181	19	crystallization	crystallization	NOUN
admet-1586	181	20	,	,	PUNCT
admet-1586	181	21	which	which	PRON
admet-1586	181	22	was	be	AUX
admet-1586	181	23	affected	affect	VERB
admet-1586	181	24	by	by	ADP
admet-1586	181	25	the	the	DET
admet-1586	181	26	addition	addition	NOUN
admet-1586	181	27	of	of	ADP
admet-1586	181	28	polymeric	polymeric	ADJ
admet-1586	181	29	carriers	carrier	NOUN
admet-1586	181	30	[	[	X
admet-1586	181	31	37	37	NUM
admet-1586	181	32	]	]	PUNCT
admet-1586	181	33	.	.	PUNCT
admet-1586	182	1	in	in	ADP
admet-1586	182	2	addition	addition	NOUN
admet-1586	182	3	,	,	PUNCT
admet-1586	182	4	the	the	DET
admet-1586	182	5	effect	effect	NOUN
admet-1586	182	6	of	of	ADP
admet-1586	182	7	hpmcas	hpmca	NOUN
admet-1586	182	8	on	on	ADP
admet-1586	182	9	the	the	DET
admet-1586	182	10	drug	drug	NOUN
admet-1586	182	11	-	-	PUNCT
admet-1586	182	12	rich	rich	ADJ
admet-1586	182	13	phase	phase	NOUN
admet-1586	182	14	of	of	ADP
admet-1586	182	15	atazanavir	atazanavir	PROPN
admet-1586	182	16	was	be	AUX
admet-1586	182	17	studied	study	VERB
admet-1586	182	18	.	.	PUNCT
admet-1586	183	1	the	the	DET
admet-1586	183	2	distribution	distribution	NOUN
admet-1586	183	3	of	of	ADP
admet-1586	183	4	hpmcas	hpmca	NOUN
admet-1586	183	5	into	into	ADP
admet-1586	183	6	a	a	DET
admet-1586	183	7	drug	drug	NOUN
admet-1586	183	8	-	-	PUNCT
admet-1586	183	9	rich	rich	ADJ
admet-1586	183	10	phase	phase	NOUN
admet-1586	183	11	did	do	AUX
admet-1586	183	12	not	not	PART
admet-1586	183	13	agree	agree	VERB
admet-1586	183	14	between	between	ADP
admet-1586	183	15	different	different	ADJ
admet-1586	183	16	grades	grade	NOUN
admet-1586	183	17	,	,	PUNCT
admet-1586	183	18	resulting	result	VERB
admet-1586	183	19	in	in	ADP
admet-1586	183	20	dissolution	dissolution	ADJ
admet-1586	183	21	performance	performance	NOUN
admet-1586	183	22	[	[	X
admet-1586	183	23	38	38	NUM
admet-1586	183	24	]	]	PUNCT
admet-1586	183	25	.	.	PUNCT
admet-1586	184	1	structural	structural	ADJ
admet-1586	184	2	conformation	conformation	NOUN
admet-1586	184	3	of	of	ADP
admet-1586	184	4	hpmcas	hpmca	NOUN
admet-1586	184	5	with	with	ADP
admet-1586	184	6	random	random	ADJ
admet-1586	184	7	-	-	PUNCT
admet-1586	184	8	coil	coil	NOUN
admet-1586	184	9	or	or	CCONJ
admet-1586	184	10	aggregation	aggregation	NOUN
admet-1586	184	11	affected	affect	VERB
admet-1586	184	12	the	the	DET
admet-1586	184	13	supersaturation	supersaturation	NOUN
admet-1586	184	14	state	state	NOUN
admet-1586	184	15	of	of	ADP
admet-1586	184	16	the	the	DET
admet-1586	184	17	drug	drug	NOUN
admet-1586	184	18	;	;	PUNCT
admet-1586	184	19	change	change	NOUN
admet-1586	184	20	in	in	ADP
admet-1586	184	21	the	the	DET
admet-1586	184	22	conformation	conformation	NOUN
admet-1586	184	23	between	between	ADP
admet-1586	184	24	grades	grade	NOUN
admet-1586	184	25	of	of	ADP
admet-1586	184	26	hpmcas	hpmca	NOUN
admet-1586	184	27	impacted	impact	VERB
admet-1586	184	28	the	the	DET
admet-1586	184	29	supersaturation	supersaturation	NOUN
admet-1586	184	30	of	of	ADP
admet-1586	184	31	celecoxib	celecoxib	NOUN
admet-1586	184	32	[	[	X
admet-1586	184	33	39	39	NUM
admet-1586	184	34	]	]	PUNCT
admet-1586	184	35	.	.	PUNCT
admet-1586	185	1	these	these	DET
admet-1586	185	2	findings	finding	NOUN
admet-1586	185	3	suggest	suggest	VERB
admet-1586	185	4	that	that	SCONJ
admet-1586	185	5	both	both	DET
admet-1586	185	6	grades	grade	NOUN
admet-1586	185	7	of	of	ADP
admet-1586	185	8	hpmcas	hpmca	NOUN
admet-1586	185	9	in	in	ADP
admet-1586	185	10	te	te	ADP
admet-1586	185	11	n	n	PROPN
admet-1586	185	12	s	s	VERB
admet-1586	185	13	it	it	PRON
admet-1586	185	14	y	y	PROPN
admet-1586	185	15	2	2	NUM
admet-1586	185	16	-	-	PUNCT
admet-1586	185	17	theta	theta	NOUN
admet-1586	185	18	(	(	PUNCT
admet-1586	185	19			NOUN
admet-1586	185	20	)	)	PUNCT
admet-1586	185	21	5	5	NUM
admet-1586	185	22	2510	2510	NUM
admet-1586	185	23	15	15	NUM
admet-1586	185	24	20	20	NUM
admet-1586	185	25	before	before	ADP
admet-1586	185	26	storage	storage	NOUN
admet-1586	185	27	3	3	NUM
admet-1586	185	28	months	month	NOUN
admet-1586	185	29	at	at	ADP
admet-1586	185	30	40c	40c	NOUN
admet-1586	185	31	before	before	ADP
admet-1586	185	32	storage	storage	NOUN
admet-1586	185	33	3	3	NUM
admet-1586	185	34	months	month	NOUN
admet-1586	185	35	at	at	ADP
admet-1586	185	36	40c	40c	NUM
admet-1586	185	37	imc	imc	PROPN
admet-1586	185	38	-	-	PUNCT
admet-1586	185	39	mg	mg	PROPN
admet-1586	185	40	(	(	PUNCT
admet-1586	185	41	20:80	20:80	NUM
admet-1586	185	42	)	)	PUNCT
admet-1586	185	43	imc	imc	PROPN
admet-1586	185	44	-	-	PUNCT
admet-1586	185	45	mx	mx	PROPN
admet-1586	185	46	(	(	PUNCT
admet-1586	185	47	20:80	20:80	NUM
admet-1586	185	48	)	)	PUNCT
admet-1586	185	49	admet	admet	PROPN
admet-1586	185	50	&	&	CCONJ
admet-1586	185	51	dmpk	dmpk	PROPN
admet-1586	185	52	11(3	11(3	NUM
admet-1586	185	53	)	)	PUNCT
admet-1586	185	54	(	(	PUNCT
admet-1586	185	55	2023	2023	NUM
admet-1586	185	56	)	)	PUNCT
admet-1586	185	57	373	373	NUM
admet-1586	185	58	-	-	SYM
admet-1586	185	59	385	385	NUM
admet-1586	185	60	dissolution	dissolution	NOUN
admet-1586	185	61	-	-	PUNCT
admet-1586	185	62	permeation	permeation	NOUN
admet-1586	185	63	of	of	ADP
admet-1586	185	64	hot	hot	ADJ
admet-1586	185	65	-	-	PUNCT
admet-1586	185	66	melt	melt	NOUN
admet-1586	185	67	extruded	extrude	VERB
admet-1586	185	68	asd	asd	NOUN
admet-1586	185	69	doi	doi	PROPN
admet-1586	185	70	:	:	PUNCT
admet-1586	185	71	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	NOUN
admet-1586	185	72	381	381	NUM
admet-1586	185	73	used	use	VERB
admet-1586	185	74	in	in	ADP
admet-1586	185	75	this	this	DET
admet-1586	185	76	study	study	NOUN
admet-1586	185	77	formed	form	VERB
admet-1586	185	78	similar	similar	ADJ
admet-1586	185	79	interactions	interaction	NOUN
admet-1586	185	80	with	with	ADP
admet-1586	185	81	imc	imc	PROPN
admet-1586	185	82	in	in	ADP
admet-1586	185	83	a	a	DET
admet-1586	185	84	supersaturated	supersaturated	ADJ
admet-1586	185	85	solution	solution	NOUN
admet-1586	185	86	,	,	PUNCT
admet-1586	185	87	resulting	result	VERB
admet-1586	185	88	in	in	ADP
admet-1586	185	89	comparable	comparable	ADJ
admet-1586	185	90	results	result	NOUN
admet-1586	185	91	for	for	ADP
admet-1586	185	92	the	the	DET
admet-1586	185	93	initial	initial	ADJ
admet-1586	185	94	dissolution	dissolution	NOUN
admet-1586	185	95	rate	rate	NOUN
admet-1586	185	96	and	and	CCONJ
admet-1586	185	97	concentration	concentration	NOUN
admet-1586	185	98	at	at	ADP
admet-1586	185	99	a	a	DET
admet-1586	185	100	plateau	plateau	NOUN
admet-1586	185	101	between	between	ADP
admet-1586	185	102	420	420	NUM
admet-1586	185	103	and	and	CCONJ
admet-1586	185	104	480	480	NUM
admet-1586	185	105	min	min	NOUN
admet-1586	185	106	.	.	PROPN
admet-1586	186	1	(	(	PUNCT
admet-1586	186	2	a	a	X
admet-1586	186	3	)	)	PUNCT
admet-1586	186	4	(	(	PUNCT
admet-1586	186	5	b	b	NOUN
admet-1586	186	6	)	)	PUNCT
admet-1586	186	7	time	time	NOUN
admet-1586	186	8	,	,	PUNCT
admet-1586	186	9	min	min	PROPN
admet-1586	186	10	time	time	NOUN
admet-1586	186	11	,	,	PUNCT
admet-1586	186	12	min	min	NOUN
admet-1586	186	13	figure	figure	NOUN
admet-1586	186	14	6	6	NUM
admet-1586	186	15	.	.	PUNCT
admet-1586	187	1	dissolution	dissolution	ADJ
admet-1586	187	2	profiles	profile	NOUN
admet-1586	187	3	of	of	ADP
admet-1586	187	4	crystalline	crystalline	PROPN
admet-1586	187	5	imc	imc	PROPN
admet-1586	187	6	and	and	CCONJ
admet-1586	187	7	solid	solid	ADJ
admet-1586	187	8	dispersions	dispersion	NOUN
admet-1586	187	9	of	of	ADP
admet-1586	187	10	imc	imc	PROPN
admet-1586	187	11	-	-	PUNCT
admet-1586	187	12	mg	mg	PROPN
admet-1586	187	13	(	(	PUNCT
admet-1586	187	14	20:80	20:80	NUM
admet-1586	187	15	)	)	PUNCT
admet-1586	187	16	and	and	CCONJ
admet-1586	187	17	imc	imc	PROPN
admet-1586	187	18	-	-	PUNCT
admet-1586	187	19	mx	mx	PROPN
admet-1586	187	20	(	(	PUNCT
admet-1586	187	21	20:80	20:80	NUM
admet-1586	187	22	)	)	PUNCT
admet-1586	187	23	in	in	ADP
admet-1586	187	24	the	the	DET
admet-1586	187	25	range	range	NOUN
admet-1586	187	26	of	of	ADP
admet-1586	187	27	(	(	PUNCT
admet-1586	187	28	a	a	X
admet-1586	187	29	)	)	PUNCT
admet-1586	187	30	0	0	NUM
admet-1586	187	31	-	-	SYM
admet-1586	187	32	480	480	NUM
admet-1586	187	33	min	min	NOUN
admet-1586	187	34	and	and	CCONJ
admet-1586	187	35	(	(	PUNCT
admet-1586	187	36	b	b	NOUN
admet-1586	187	37	)	)	PUNCT
admet-1586	187	38	0	0	NUM
admet-1586	187	39	-	-	SYM
admet-1586	187	40	2.0	2.0	NUM
admet-1586	187	41	min	min	NOUN
admet-1586	187	42	.	.	PUNCT
admet-1586	188	1	the	the	DET
admet-1586	188	2	error	error	NOUN
admet-1586	188	3	bars	bar	NOUN
admet-1586	188	4	represent	represent	VERB
admet-1586	188	5	a	a	DET
admet-1586	188	6	standard	standard	ADJ
admet-1586	188	7	deviation	deviation	NOUN
admet-1586	188	8	of	of	ADP
admet-1586	188	9	n	n	NOUN
admet-1586	188	10	=	=	SYM
admet-1586	188	11	3	3	X
admet-1586	188	12	.	.	X
admet-1586	188	13	figure	figure	NOUN
admet-1586	188	14	7a	7a	PROPN
admet-1586	188	15	shows	show	VERB
admet-1586	188	16	the	the	DET
admet-1586	188	17	permeation	permeation	NOUN
admet-1586	188	18	profiles	profile	NOUN
admet-1586	188	19	of	of	ADP
admet-1586	188	20	crystalline	crystalline	PROPN
admet-1586	188	21	imc	imc	PROPN
admet-1586	188	22	and	and	CCONJ
admet-1586	188	23	the	the	DET
admet-1586	188	24	solid	solid	ADJ
admet-1586	188	25	dispersions	dispersion	NOUN
admet-1586	188	26	of	of	ADP
admet-1586	188	27	imc	imc	PROPN
admet-1586	188	28	-	-	PUNCT
admet-1586	188	29	mg	mg	PROPN
admet-1586	188	30	(	(	PUNCT
admet-1586	188	31	20:80	20:80	NUM
admet-1586	188	32	)	)	PUNCT
admet-1586	188	33	and	and	CCONJ
admet-1586	188	34	imc	imc	PROPN
admet-1586	188	35	-	-	PUNCT
admet-1586	188	36	mx	mx	PROPN
admet-1586	188	37	(	(	PUNCT
admet-1586	188	38	20:80	20:80	NUM
admet-1586	188	39	)	)	PUNCT
admet-1586	188	40	.	.	PUNCT
admet-1586	189	1	the	the	DET
admet-1586	189	2	concentrations	concentration	NOUN
admet-1586	189	3	of	of	ADP
admet-1586	189	4	imc	imc	PROPN
admet-1586	189	5	linearly	linearly	ADV
admet-1586	189	6	increased	increase	VERB
admet-1586	189	7	depending	depend	VERB
admet-1586	189	8	on	on	ADP
admet-1586	189	9	experimental	experimental	ADJ
admet-1586	189	10	time	time	NOUN
admet-1586	189	11	for	for	ADP
admet-1586	189	12	all	all	DET
admet-1586	189	13	samples	sample	NOUN
admet-1586	189	14	;	;	PUNCT
admet-1586	189	15	both	both	CCONJ
admet-1586	189	16	the	the	DET
admet-1586	189	17	solid	solid	ADJ
admet-1586	189	18	dispersions	dispersion	NOUN
admet-1586	189	19	showed	show	VERB
admet-1586	189	20	a	a	DET
admet-1586	189	21	reduction	reduction	NOUN
admet-1586	189	22	in	in	ADP
admet-1586	189	23	lag	lag	NOUN
admet-1586	189	24	-	-	PUNCT
admet-1586	189	25	time	time	NOUN
admet-1586	189	26	from	from	ADP
admet-1586	189	27	around	around	ADP
admet-1586	189	28	100	100	NUM
admet-1586	189	29	to	to	PART
admet-1586	189	30	60	60	NUM
admet-1586	189	31	-	-	SYM
admet-1586	189	32	65	65	NUM
admet-1586	189	33	min	min	NOUN
admet-1586	189	34	and	and	CCONJ
admet-1586	189	35	a	a	DET
admet-1586	189	36	higher	high	ADJ
admet-1586	189	37	concentration	concentration	NOUN
admet-1586	189	38	than	than	ADP
admet-1586	189	39	that	that	PRON
admet-1586	189	40	of	of	ADP
admet-1586	189	41	crystalline	crystalline	PROPN
admet-1586	189	42	imc	imc	PROPN
admet-1586	189	43	.	.	PUNCT
admet-1586	190	1	the	the	DET
admet-1586	190	2	concentrations	concentration	NOUN
admet-1586	190	3	of	of	ADP
admet-1586	190	4	all	all	PRON
admet-1586	190	5	of	of	ADP
admet-1586	190	6	the	the	DET
admet-1586	190	7	samples	sample	NOUN
admet-1586	190	8	were	be	AUX
admet-1586	190	9	within	within	ADP
admet-1586	190	10	100	100	NUM
admet-1586	190	11	mg	mg	NUM
admet-1586	190	12	ml-1	ml-1	PROPN
admet-1586	190	13	.	.	PUNCT
admet-1586	191	1	the	the	DET
admet-1586	191	2	solubility	solubility	NOUN
admet-1586	191	3	test	test	NOUN
admet-1586	191	4	result	result	NOUN
admet-1586	191	5	for	for	ADP
admet-1586	191	6	crystalline	crystalline	NOUN
admet-1586	191	7	imc	imc	NOUN
admet-1586	191	8	in	in	ADP
admet-1586	191	9	the	the	DET
admet-1586	191	10	acceptor	acceptor	NOUN
admet-1586	191	11	medium	medium	NOUN
admet-1586	191	12	was	be	AUX
admet-1586	191	13	1.840.39	1.840.39	NUM
admet-1586	191	14	mg	mg	NUM
admet-1586	191	15	ml-1	ml-1	PROPN
admet-1586	191	16	.	.	PROPN
admet-1586	192	1	imc	imc	PROPN
admet-1586	192	2	is	be	AUX
admet-1586	192	3	an	an	DET
admet-1586	192	4	acidic	acidic	ADJ
admet-1586	192	5	drug	drug	NOUN
admet-1586	192	6	,	,	PUNCT
admet-1586	192	7	and	and	CCONJ
admet-1586	192	8	its	its	PRON
admet-1586	192	9	solubility	solubility	NOUN
admet-1586	192	10	increase	increase	NOUN
admet-1586	192	11	is	be	AUX
admet-1586	192	12	ph	ph	ADJ
admet-1586	192	13	-	-	ADJ
admet-1586	192	14	dependent	dependent	ADJ
admet-1586	192	15	,	,	PUNCT
admet-1586	192	16	especially	especially	ADV
admet-1586	192	17	at	at	ADP
admet-1586	192	18	ph	ph	ADJ
admet-1586	192	19	values	value	NOUN
admet-1586	192	20	greater	great	ADJ
admet-1586	192	21	than	than	ADP
admet-1586	192	22	4	4	NUM
admet-1586	192	23	[	[	SYM
admet-1586	192	24	40	40	NUM
admet-1586	192	25	]	]	PUNCT
admet-1586	192	26	.	.	PUNCT
admet-1586	193	1	this	this	DET
admet-1586	193	2	result	result	NOUN
admet-1586	193	3	suggests	suggest	VERB
admet-1586	193	4	that	that	SCONJ
admet-1586	193	5	in	in	ADP
admet-1586	193	6	all	all	DET
admet-1586	193	7	samples	sample	NOUN
admet-1586	193	8	,	,	PUNCT
admet-1586	193	9	imc	imc	PROPN
admet-1586	193	10	was	be	AUX
admet-1586	193	11	not	not	PART
admet-1586	193	12	saturated	saturate	VERB
admet-1586	193	13	in	in	ADP
admet-1586	193	14	the	the	DET
admet-1586	193	15	acceptor	acceptor	NOUN
admet-1586	193	16	medium	medium	NOUN
admet-1586	193	17	during	during	ADP
admet-1586	193	18	the	the	DET
admet-1586	193	19	dissolutionpermeation	dissolutionpermeation	NOUN
admet-1586	193	20	test	test	NOUN
admet-1586	193	21	.	.	PUNCT
admet-1586	194	1	the	the	DET
admet-1586	194	2	slope	slope	NOUN
admet-1586	194	3	of	of	ADP
admet-1586	194	4	the	the	DET
admet-1586	194	5	samples	sample	NOUN
admet-1586	194	6	with	with	ADP
admet-1586	194	7	concentration	concentration	NOUN
admet-1586	194	8	and	and	CCONJ
admet-1586	194	9	time	time	NOUN
admet-1586	194	10	were	be	AUX
admet-1586	194	11	calculated	calculate	VERB
admet-1586	194	12	in	in	ADP
admet-1586	194	13	the	the	DET
admet-1586	194	14	range	range	NOUN
admet-1586	194	15	of	of	ADP
admet-1586	194	16	420	420	NUM
admet-1586	194	17	to	to	PART
admet-1586	194	18	480	480	NUM
admet-1586	194	19	min	min	NOUN
admet-1586	194	20	,	,	PUNCT
admet-1586	194	21	in	in	ADP
admet-1586	194	22	which	which	PRON
admet-1586	194	23	the	the	DET
admet-1586	194	24	dissolution	dissolution	NOUN
admet-1586	194	25	almost	almost	ADV
admet-1586	194	26	attained	attain	VERB
admet-1586	194	27	a	a	DET
admet-1586	194	28	plateau	plateau	NOUN
admet-1586	194	29	,	,	PUNCT
admet-1586	194	30	as	as	SCONJ
admet-1586	194	31	described	describe	VERB
admet-1586	194	32	in	in	ADP
admet-1586	194	33	figure	figure	NOUN
admet-1586	194	34	7a	7a	NUM
admet-1586	194	35	.	.	PUNCT
admet-1586	195	1	figure	figure	NOUN
admet-1586	195	2	7b	7b	PROPN
admet-1586	195	3	shows	show	VERB
admet-1586	195	4	the	the	DET
admet-1586	195	5	permeation	permeation	NOUN
admet-1586	195	6	profiles	profile	NOUN
admet-1586	195	7	of	of	ADP
admet-1586	195	8	the	the	DET
admet-1586	195	9	samples	sample	NOUN
admet-1586	195	10	in	in	ADP
admet-1586	195	11	the	the	DET
admet-1586	195	12	range	range	NOUN
admet-1586	195	13	of	of	ADP
admet-1586	195	14	420	420	NUM
admet-1586	195	15	to	to	PART
admet-1586	195	16	480	480	NUM
admet-1586	195	17	min	min	NOUN
admet-1586	195	18	.	.	PUNCT
admet-1586	196	1	the	the	DET
admet-1586	196	2	slope	slope	NOUN
admet-1586	196	3	of	of	ADP
admet-1586	196	4	crystalline	crystalline	PROPN
admet-1586	196	5	imc	imc	PROPN
admet-1586	196	6	was	be	AUX
admet-1586	196	7	0.11	0.11	NUM
admet-1586	196	8	(	(	PUNCT
admet-1586	196	9	µg	µg	ADV
admet-1586	196	10	ml-1	ml-1	X
admet-1586	196	11	)	)	PUNCT
admet-1586	196	12	min-1	min-1	NOUN
admet-1586	196	13	,	,	PUNCT
admet-1586	196	14	while	while	SCONJ
admet-1586	196	15	those	those	PRON
admet-1586	196	16	of	of	ADP
admet-1586	196	17	the	the	DET
admet-1586	196	18	solid	solid	ADJ
admet-1586	196	19	dispersion	dispersion	NOUN
admet-1586	196	20	of	of	ADP
admet-1586	196	21	imc	imc	PROPN
admet-1586	196	22	-	-	PUNCT
admet-1586	196	23	mg	mg	PROPN
admet-1586	196	24	(	(	PUNCT
admet-1586	196	25	20:80	20:80	NUM
admet-1586	196	26	)	)	PUNCT
admet-1586	196	27	and	and	CCONJ
admet-1586	196	28	imc	imc	PROPN
admet-1586	196	29	-	-	PUNCT
admet-1586	196	30	mx	mx	PROPN
admet-1586	196	31	(	(	PUNCT
admet-1586	196	32	20:80	20:80	NUM
admet-1586	196	33	)	)	PUNCT
admet-1586	196	34	were	be	AUX
admet-1586	196	35	0.21	0.21	NUM
admet-1586	196	36	and	and	CCONJ
admet-1586	196	37	0.20	0.20	NUM
admet-1586	196	38	(	(	PUNCT
admet-1586	196	39	µg	µg	ADV
admet-1586	196	40	ml-1	ml-1	X
admet-1586	196	41	)	)	PUNCT
admet-1586	196	42	min-1	min-1	NOUN
admet-1586	196	43	,	,	PUNCT
admet-1586	196	44	respectively	respectively	ADV
admet-1586	196	45	.	.	PUNCT
admet-1586	197	1	the	the	DET
admet-1586	197	2	flux	flux	NOUN
admet-1586	197	3	values	value	VERB
admet-1586	197	4	through	through	ADP
admet-1586	197	5	the	the	DET
admet-1586	197	6	membrane	membrane	NOUN
admet-1586	197	7	were	be	AUX
admet-1586	197	8	measured	measure	VERB
admet-1586	197	9	for	for	ADP
admet-1586	197	10	crystalline	crystalline	NOUN
admet-1586	197	11	imc	imc	PROPN
admet-1586	197	12	,	,	PUNCT
admet-1586	197	13	and	and	CCONJ
admet-1586	197	14	the	the	DET
admet-1586	197	15	solid	solid	ADJ
admet-1586	197	16	dispersions	dispersion	NOUN
admet-1586	197	17	of	of	ADP
admet-1586	197	18	imc	imc	PROPN
admet-1586	197	19	-	-	PUNCT
admet-1586	197	20	mg	mg	PROPN
admet-1586	197	21	(	(	PUNCT
admet-1586	197	22	20:80	20:80	NUM
admet-1586	197	23	)	)	PUNCT
admet-1586	197	24	and	and	CCONJ
admet-1586	197	25	imc	imc	PROPN
admet-1586	197	26	-	-	PUNCT
admet-1586	197	27	mx	mx	PROPN
admet-1586	197	28	(	(	PUNCT
admet-1586	197	29	20:80	20:80	NUM
admet-1586	197	30	)	)	PUNCT
admet-1586	197	31	were	be	AUX
admet-1586	197	32	measured	measure	VERB
admet-1586	197	33	according	accord	VERB
admet-1586	197	34	to	to	ADP
admet-1586	197	35	the	the	DET
admet-1586	197	36	previously	previously	ADV
admet-1586	197	37	described	describe	VERB
admet-1586	197	38	process	process	NOUN
admet-1586	198	1	[	[	X
admet-1586	198	2	23	23	NUM
admet-1586	198	3	-	-	SYM
admet-1586	198	4	24	24	NUM
admet-1586	198	5	]	]	PUNCT
admet-1586	198	6	.	.	PUNCT
admet-1586	199	1	the	the	DET
admet-1586	199	2	calculated	calculated	ADJ
admet-1586	199	3	flux	flux	NOUN
admet-1586	199	4	values	value	NOUN
admet-1586	199	5	of	of	ADP
admet-1586	199	6	crystalline	crystalline	NOUN
admet-1586	199	7	imc	imc	PROPN
admet-1586	199	8	and	and	CCONJ
admet-1586	199	9	the	the	DET
admet-1586	199	10	solid	solid	ADJ
admet-1586	199	11	dispersions	dispersion	NOUN
admet-1586	199	12	of	of	ADP
admet-1586	199	13	imc	imc	PROPN
admet-1586	199	14	-	-	PUNCT
admet-1586	199	15	mg	mg	PROPN
admet-1586	199	16	(	(	PUNCT
admet-1586	199	17	20:80	20:80	NUM
admet-1586	199	18	)	)	PUNCT
admet-1586	199	19	and	and	CCONJ
admet-1586	199	20	imc	imc	PROPN
admet-1586	199	21	-	-	PUNCT
admet-1586	199	22	mx	mx	PROPN
admet-1586	199	23	(	(	PUNCT
admet-1586	199	24	20:80	20:80	NUM
admet-1586	199	25	)	)	PUNCT
admet-1586	199	26	were	be	AUX
admet-1586	199	27	1.38	1.38	NUM
admet-1586	199	28	,	,	PUNCT
admet-1586	199	29	2.71	2.71	NUM
admet-1586	199	30	,	,	PUNCT
admet-1586	199	31	and	and	CCONJ
admet-1586	199	32	2.60	2.60	NUM
admet-1586	199	33	(	(	PUNCT
admet-1586	199	34	µg	µg	NOUN
admet-1586	199	35	min-1	min-1	NOUN
admet-1586	199	36	)	)	PUNCT
admet-1586	199	37	cm-2	cm-2	NOUN
admet-1586	199	38	,	,	PUNCT
admet-1586	199	39	respectively	respectively	ADV
admet-1586	199	40	.	.	PUNCT
admet-1586	200	1	formulation	formulation	NOUN
admet-1586	200	2	of	of	ADP
admet-1586	200	3	the	the	DET
admet-1586	200	4	solid	solid	ADJ
admet-1586	200	5	dispersions	dispersion	NOUN
admet-1586	200	6	resulted	result	VERB
admet-1586	200	7	in	in	ADP
admet-1586	200	8	an	an	DET
admet-1586	200	9	approximately	approximately	ADV
admet-1586	200	10	two	two	NUM
admet-1586	200	11	-	-	ADJ
admet-1586	200	12	fold	fold	ADJ
admet-1586	200	13	increase	increase	NOUN
admet-1586	200	14	in	in	ADP
admet-1586	200	15	the	the	DET
admet-1586	200	16	flux	flux	NOUN
admet-1586	200	17	value	value	NOUN
admet-1586	200	18	of	of	ADP
admet-1586	200	19	imc	imc	PROPN
admet-1586	200	20	;	;	PUNCT
admet-1586	200	21	no	no	DET
admet-1586	200	22	significant	significant	ADJ
admet-1586	200	23	differences	difference	NOUN
admet-1586	200	24	in	in	ADP
admet-1586	200	25	the	the	DET
admet-1586	200	26	flux	flux	NOUN
admet-1586	200	27	values	value	NOUN
admet-1586	200	28	were	be	AUX
admet-1586	200	29	observed	observe	VERB
admet-1586	200	30	between	between	ADP
admet-1586	200	31	the	the	DET
admet-1586	200	32	two	two	NUM
admet-1586	200	33	solid	solid	ADJ
admet-1586	200	34	dispersions	dispersion	NOUN
admet-1586	200	35	.	.	PUNCT
admet-1586	201	1	it	it	PRON
admet-1586	201	2	is	be	AUX
admet-1586	201	3	known	know	VERB
admet-1586	201	4	that	that	SCONJ
admet-1586	201	5	the	the	DET
admet-1586	201	6	membrane	membrane	NOUN
admet-1586	201	7	permeability	permeability	NOUN
admet-1586	201	8	is	be	AUX
admet-1586	201	9	affected	affect	VERB
admet-1586	201	10	by	by	ADP
admet-1586	201	11	the	the	DET
admet-1586	201	12	formation	formation	NOUN
admet-1586	201	13	of	of	ADP
admet-1586	201	14	drug	drug	NOUN
admet-1586	201	15	-	-	PUNCT
admet-1586	201	16	rich	rich	ADJ
admet-1586	201	17	colloids	colloid	NOUN
admet-1586	201	18	in	in	ADP
admet-1586	201	19	the	the	DET
admet-1586	201	20	supersaturation	supersaturation	NOUN
admet-1586	201	21	state	state	NOUN
admet-1586	201	22	;	;	PUNCT
admet-1586	201	23	polymers	polymer	NOUN
admet-1586	201	24	used	use	VERB
admet-1586	201	25	as	as	ADP
admet-1586	201	26	solid	solid	ADJ
admet-1586	201	27	dispersion	dispersion	NOUN
admet-1586	201	28	carriers	carrier	NOUN
admet-1586	201	29	were	be	AUX
admet-1586	201	30	distributed	distribute	VERB
admet-1586	201	31	into	into	ADP
admet-1586	201	32	drug	drug	NOUN
admet-1586	201	33	-	-	PUNCT
admet-1586	201	34	rich	rich	ADJ
admet-1586	201	35	colloids	colloid	NOUN
admet-1586	201	36	,	,	PUNCT
admet-1586	201	37	which	which	PRON
admet-1586	201	38	stabilized	stabilize	VERB
admet-1586	201	39	the	the	DET
admet-1586	201	40	drug	drug	NOUN
admet-1586	201	41	[	[	X
admet-1586	201	42	36	36	NUM
admet-1586	201	43	-	-	SYM
admet-1586	201	44	38	38	NUM
admet-1586	201	45	]	]	PUNCT
admet-1586	201	46	.	.	PUNCT
admet-1586	202	1	resistance	resistance	NOUN
admet-1586	202	2	of	of	ADP
admet-1586	202	3	diffusion	diffusion	NOUN
admet-1586	202	4	across	across	ADP
admet-1586	202	5	the	the	DET
admet-1586	202	6	unstirred	unstirred	ADJ
admet-1586	202	7	water	water	NOUN
admet-1586	202	8	layer	layer	NOUN
admet-1586	202	9	was	be	AUX
admet-1586	202	10	reduced	reduce	VERB
admet-1586	202	11	by	by	ADP
admet-1586	202	12	the	the	DET
admet-1586	202	13	drugrich	drugrich	NOUN
admet-1586	202	14	colloids	colloid	NOUN
admet-1586	202	15	,	,	PUNCT
admet-1586	202	16	resulting	result	VERB
admet-1586	202	17	in	in	ADP
admet-1586	202	18	enhanced	enhanced	ADJ
admet-1586	202	19	membrane	membrane	NOUN
admet-1586	202	20	penetration	penetration	NOUN
admet-1586	202	21	[	[	X
admet-1586	202	22	24	24	NUM
admet-1586	202	23	]	]	PUNCT
admet-1586	202	24	.	.	PUNCT
admet-1586	203	1	the	the	DET
admet-1586	203	2	sizes	size	NOUN
admet-1586	203	3	of	of	ADP
admet-1586	203	4	the	the	DET
admet-1586	203	5	drug	drug	NOUN
admet-1586	203	6	-	-	PUNCT
admet-1586	203	7	rich	rich	ADJ
admet-1586	203	8	colloids	colloid	NOUN
admet-1586	203	9	of	of	ADP
admet-1586	203	10	the	the	DET
admet-1586	203	11	solid	solid	ADJ
admet-1586	203	12	dispersions	dispersion	NOUN
admet-1586	203	13	in	in	ADP
admet-1586	203	14	the	the	DET
admet-1586	203	15	acceptor	acceptor	NOUN
admet-1586	203	16	buffer	buffer	NOUN
admet-1586	203	17	were	be	AUX
admet-1586	203	18	measured	measure	VERB
admet-1586	203	19	;	;	PUNCT
admet-1586	203	20	the	the	DET
admet-1586	203	21	average	average	ADJ
admet-1586	203	22	sizes	size	NOUN
admet-1586	203	23	were	be	AUX
admet-1586	203	24	140.2	140.2	NUM
admet-1586	203	25	and	and	CCONJ
admet-1586	203	26	148.5	148.5	NUM
admet-1586	203	27	nm	nm	NOUN
admet-1586	203	28	for	for	ADP
admet-1586	203	29	the	the	DET
admet-1586	203	30	solid	solid	ADJ
admet-1586	203	31	dispersion	dispersion	NOUN
admet-1586	203	32	imc	imc	PROPN
admet-1586	203	33	-	-	PUNCT
admet-1586	203	34	mg	mg	PROPN
admet-1586	203	35	(	(	PUNCT
admet-1586	203	36	20:80	20:80	NUM
admet-1586	203	37	)	)	PUNCT
admet-1586	203	38	and	and	CCONJ
admet-1586	203	39	imc	imc	PROPN
admet-1586	203	40	-	-	PUNCT
admet-1586	203	41	mx	mx	PROPN
admet-1586	203	42	(	(	PUNCT
admet-1586	203	43	20:80	20:80	NUM
admet-1586	203	44	)	)	PUNCT
admet-1586	203	45	,	,	PUNCT
admet-1586	203	46	respectively	respectively	ADV
admet-1586	203	47	,	,	PUNCT
admet-1586	203	48	showing	show	VERB
admet-1586	203	49	no	no	DET
admet-1586	203	50	significant	significant	ADJ
admet-1586	203	51	difference	difference	NOUN
admet-1586	203	52	.	.	PUNCT
admet-1586	204	1	hence	hence	ADV
admet-1586	204	2	,	,	PUNCT
admet-1586	204	3	it	it	PRON
admet-1586	204	4	is	be	AUX
admet-1586	204	5	suggested	suggest	VERB
admet-1586	204	6	that	that	SCONJ
admet-1586	204	7	the	the	DET
admet-1586	204	8	effects	effect	NOUN
admet-1586	204	9	of	of	ADP
admet-1586	204	10	hpmcas	hpmca	NOUN
admet-1586	204	11	-	-	PUNCT
admet-1586	204	12	mg	mg	PROPN
admet-1586	204	13	and	and	CCONJ
admet-1586	204	14	hpmcas	hpmca	NOUN
admet-1586	204	15	-	-	PUNCT
admet-1586	204	16	mx	mx	NOUN
admet-1586	204	17	on	on	ADP
admet-1586	204	18	drug	drug	NOUN
admet-1586	204	19	-	-	PUNCT
admet-1586	204	20	rich	rich	ADJ
admet-1586	204	21	colloids	colloid	NOUN
admet-1586	204	22	are	be	AUX
admet-1586	204	23	comparable	comparable	ADJ
admet-1586	204	24	,	,	PUNCT
admet-1586	204	25	inducing	induce	VERB
admet-1586	204	26	similar	similar	ADJ
admet-1586	204	27	permeation	permeation	NOUN
admet-1586	204	28	profiles	profile	NOUN
admet-1586	204	29	and	and	CCONJ
admet-1586	204	30	the	the	DET
admet-1586	204	31	flux	flux	NOUN
admet-1586	204	32	value	value	NOUN
admet-1586	204	33	of	of	ADP
admet-1586	204	34	imc	imc	PROPN
admet-1586	204	35	.	.	PUNCT
admet-1586	205	1	the	the	DET
admet-1586	205	2	results	result	NOUN
admet-1586	205	3	of	of	ADP
admet-1586	205	4	the	the	DET
admet-1586	205	5	dissolution	dissolution	NOUN
admet-1586	205	6	and	and	CCONJ
admet-1586	205	7	permeation	permeation	NOUN
admet-1586	205	8	tests	test	NOUN
admet-1586	205	9	determined	determine	VERB
admet-1586	205	10	that	that	SCONJ
admet-1586	205	11	while	while	SCONJ
admet-1586	205	12	hpmcas	hpmca	NOUN
admet-1586	205	13	-	-	PUNCT
admet-1586	205	14	mx	mx	PROPN
admet-1586	205	15	has	have	VERB
admet-1586	205	16	a	a	DET
admet-1586	205	17	comparable	comparable	ADJ
admet-1586	205	18	ability	ability	NOUN
admet-1586	205	19	to	to	PART
admet-1586	205	20	hpmcas	hpmca	NOUN
admet-1586	205	21	-	-	PUNCT
admet-1586	205	22	mg	mg	NOUN
admet-1586	205	23	as	as	ADP
admet-1586	205	24	a	a	DET
admet-1586	205	25	solid	solid	ADJ
admet-1586	205	26	dispersion	dispersion	NOUN
admet-1586	205	27	carrier	carrier	NOUN
admet-1586	205	28	,	,	PUNCT
admet-1586	205	29	it	it	PRON
admet-1586	205	30	can	can	AUX
admet-1586	205	31	undergo	undergo	VERB
admet-1586	205	32	the	the	DET
admet-1586	205	33	hot	hot	ADJ
admet-1586	205	34	-	-	PUNCT
admet-1586	205	35	melt	melt	NOUN
admet-1586	205	36	extrusion	extrusion	NOUN
admet-1586	205	37	process	process	NOUN
admet-1586	205	38	at	at	ADP
admet-1586	205	39	a	a	DET
admet-1586	205	40	lower	low	ADJ
admet-1586	205	41	temperature	temperature	NOUN
admet-1586	205	42	.	.	PUNCT
admet-1586	206	1	d	d	X
admet-1586	206	2	is	be	AUX
admet-1586	206	3	s	s	PRON
admet-1586	206	4	o	o	X
admet-1586	206	5	lv	lv	PROPN
admet-1586	206	6	e	e	X
admet-1586	206	7	d	d	X
admet-1586	206	8	(	(	PUNCT
admet-1586	206	9	µ	µ	X
admet-1586	206	10	g	g	NOUN
admet-1586	206	11	/m	/m	SYM
admet-1586	206	12	l	l	NOUN
admet-1586	206	13	)	)	PUNCT
admet-1586	206	14	time	time	NOUN
admet-1586	206	15	(	(	PUNCT
admet-1586	206	16	min	min	NOUN
admet-1586	206	17	)	)	PUNCT
admet-1586	206	18	0	0	NUM
admet-1586	206	19	480240	480240	NUM
admet-1586	207	1	000	000	NUM
admet-1586	207	2	100	100	NUM
admet-1586	207	3	300	300	NUM
admet-1586	207	4	500	500	NUM
admet-1586	207	5	200	200	NUM
admet-1586	207	6	400	400	NUM
admet-1586	207	7	120	120	NUM
admet-1586	207	8	360	360	NUM
admet-1586	207	9	●	●	NUM
admet-1586	207	10	imc	imc	NOUN
admet-1586	207	11	-	-	PUNCT
admet-1586	207	12	mg	mg	PROPN
admet-1586	207	13	(	(	PUNCT
admet-1586	207	14	20:80	20:80	NUM
admet-1586	207	15	)	)	PUNCT
admet-1586	207	16	●	●	PUNCT
admet-1586	207	17	imc	imc	PROPN
admet-1586	207	18	-	-	PUNCT
admet-1586	207	19	mx	mx	PROPN
admet-1586	207	20	(	(	PUNCT
admet-1586	207	21	20:80	20:80	NUM
admet-1586	207	22	)	)	PUNCT
admet-1586	207	23	●	●	NUM
admet-1586	207	24	crystalline	crystalline	NOUN
admet-1586	207	25	imc	imc	NOUN
admet-1586	207	26	y	y	PROPN
admet-1586	207	27	=	=	PUNCT
admet-1586	207	28	45.959x	45.959x	PRON
admet-1586	208	1	+	+	NUM
admet-1586	208	2	7.0967	7.0967	NUM
admet-1586	208	3	r²	r²	NOUN
admet-1586	208	4	=	=	PUNCT
admet-1586	208	5	0.9889	0.9889	NUM
admet-1586	208	6	y	y	NOUN
admet-1586	208	7	=	=	SYM
admet-1586	208	8	44.343x	44.343x	NOUN
admet-1586	209	1	+	+	CCONJ
admet-1586	210	1	0.7864	0.7864	NUM
admet-1586	210	2	r²	r²	NOUN
admet-1586	210	3	=	=	NOUN
admet-1586	210	4	0.9879	0.9879	NUM
admet-1586	210	5	y	y	PROPN
admet-1586	210	6	=	=	SYM
admet-1586	210	7	1.5997x	1.5997x	PROPN
admet-1586	210	8	+	+	CCONJ
admet-1586	210	9	0.2152	0.2152	NUM
admet-1586	210	10	r²	r²	NOUN
admet-1586	210	11	=	=	NOUN
admet-1586	210	12	0.8211	0.8211	NUM
admet-1586	210	13	d	d	NOUN
admet-1586	210	14	is	be	AUX
admet-1586	210	15	s	s	PRON
admet-1586	210	16	o	o	X
admet-1586	210	17	lv	lv	PROPN
admet-1586	210	18	e	e	X
admet-1586	210	19	d	d	X
admet-1586	210	20	(	(	PUNCT
admet-1586	210	21	µ	µ	X
admet-1586	210	22	g	g	NOUN
admet-1586	210	23	/m	/m	SYM
admet-1586	210	24	l	l	NOUN
admet-1586	210	25	)	)	PUNCT
admet-1586	210	26	time	time	NOUN
admet-1586	210	27	(	(	PUNCT
admet-1586	210	28	min	min	NOUN
admet-1586	210	29	)	)	PUNCT
admet-1586	210	30	0.0	0.0	NUM
admet-1586	210	31	2.01.0	2.01.0	NUM
admet-1586	210	32	000	000	NUM
admet-1586	210	33	020	020	NUM
admet-1586	210	34	080	080	NUM
admet-1586	210	35	040	040	NUM
admet-1586	210	36	060	060	NUM
admet-1586	210	37	0.5	0.5	NUM
admet-1586	210	38	1.5	1.5	NUM
admet-1586	210	39	●	●	NUM
admet-1586	210	40	imc	imc	NOUN
admet-1586	210	41	-	-	PUNCT
admet-1586	210	42	mg	mg	PROPN
admet-1586	210	43	(	(	PUNCT
admet-1586	210	44	20:80	20:80	NUM
admet-1586	210	45	)	)	PUNCT
admet-1586	210	46	●	●	PUNCT
admet-1586	210	47	imc	imc	PROPN
admet-1586	210	48	-	-	PUNCT
admet-1586	210	49	mx	mx	PROPN
admet-1586	210	50	(	(	PUNCT
admet-1586	210	51	20:80	20:80	NUM
admet-1586	210	52	)	)	PUNCT
admet-1586	210	53	●	●	NUM
admet-1586	210	54	crystalline	crystalline	NOUN
admet-1586	210	55	imc	imc	NOUN
admet-1586	210	56	d	d	PROPN
admet-1586	210	57	es	es	X
admet-1586	210	58	ilv	ilv	PROPN
admet-1586	210	59	e	e	PROPN
admet-1586	211	1	d	d	X
admet-1586	211	2	a	a	DET
admet-1586	211	3	m	m	NOUN
admet-1586	211	4	o	o	NOUN
admet-1586	211	5	u	u	NOUN
admet-1586	211	6	n	n	PRON
admet-1586	211	7	t	t	PROPN
admet-1586	211	8	,	,	PUNCT
admet-1586	211	9	m	m	VERB
admet-1586	211	10	g	g	NOUN
admet-1586	211	11	m	m	PROPN
admet-1586	211	12	l-1	l-1	PROPN
admet-1586	211	13	d	d	PROPN
admet-1586	211	14	es	es	X
admet-1586	211	15	ilv	ilv	PROPN
admet-1586	211	16	e	e	PROPN
admet-1586	212	1	d	d	X
admet-1586	212	2	a	a	DET
admet-1586	212	3	m	m	NOUN
admet-1586	212	4	o	o	NOUN
admet-1586	212	5	u	u	NOUN
admet-1586	212	6	n	n	PRON
admet-1586	212	7	t	t	PROPN
admet-1586	212	8	,	,	PUNCT
admet-1586	212	9	m	m	VERB
admet-1586	212	10	g	g	PROPN
admet-1586	212	11	m	m	PROPN
admet-1586	212	12	l-1	l-1	PROPN
admet-1586	212	13	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	PROPN
admet-1586	212	14	h.	h.	PROPN
admet-1586	212	15	tanaka	tanaka	PROPN
admet-1586	212	16	et	et	PROPN
admet-1586	212	17	al	al	PROPN
admet-1586	212	18	.	.	PROPN
admet-1586	212	19	admet	admet	PROPN
admet-1586	212	20	&	&	CCONJ
admet-1586	212	21	dmpk	dmpk	PROPN
admet-1586	212	22	11(3	11(3	NUM
admet-1586	212	23	)	)	PUNCT
admet-1586	212	24	(	(	PUNCT
admet-1586	212	25	2023	2023	NUM
admet-1586	212	26	)	)	PUNCT
admet-1586	212	27	373	373	NUM
admet-1586	212	28	-	-	SYM
admet-1586	212	29	385	385	NUM
admet-1586	212	30	382	382	NUM
admet-1586	212	31	(	(	PUNCT
admet-1586	212	32	a	a	NOUN
admet-1586	212	33	)	)	PUNCT
admet-1586	212	34	(	(	PUNCT
admet-1586	212	35	b	b	NOUN
admet-1586	212	36	)	)	PUNCT
admet-1586	212	37	time	time	NOUN
admet-1586	212	38	,	,	PUNCT
admet-1586	212	39	min	min	PROPN
admet-1586	212	40	time	time	NOUN
admet-1586	212	41	,	,	PUNCT
admet-1586	212	42	min	min	NOUN
admet-1586	212	43	figure	figure	NOUN
admet-1586	212	44	7	7	NUM
admet-1586	212	45	.	.	PUNCT
admet-1586	212	46	permeation	permeation	NOUN
admet-1586	212	47	profiles	profile	NOUN
admet-1586	212	48	of	of	ADP
admet-1586	212	49	crystalline	crystalline	NOUN
admet-1586	212	50	imc	imc	PROPN
admet-1586	212	51	and	and	CCONJ
admet-1586	212	52	solid	solid	ADJ
admet-1586	212	53	dispersions	dispersion	NOUN
admet-1586	212	54	of	of	ADP
admet-1586	212	55	imc	imc	PROPN
admet-1586	212	56	-	-	PUNCT
admet-1586	212	57	mg	mg	PROPN
admet-1586	212	58	(	(	PUNCT
admet-1586	212	59	20:80	20:80	NUM
admet-1586	212	60	)	)	PUNCT
admet-1586	212	61	and	and	CCONJ
admet-1586	212	62	imc	imc	PROPN
admet-1586	212	63	-	-	PUNCT
admet-1586	212	64	mx	mx	PROPN
admet-1586	212	65	(	(	PUNCT
admet-1586	212	66	20:80	20:80	NUM
admet-1586	212	67	)	)	PUNCT
admet-1586	212	68	in	in	ADP
admet-1586	212	69	the	the	DET
admet-1586	212	70	range	range	NOUN
admet-1586	212	71	of	of	ADP
admet-1586	212	72	(	(	PUNCT
admet-1586	212	73	a	a	X
admet-1586	212	74	)	)	PUNCT
admet-1586	212	75	0	0	NUM
admet-1586	212	76	-	-	SYM
admet-1586	212	77	480	480	NUM
admet-1586	212	78	min	min	NOUN
admet-1586	212	79	and	and	CCONJ
admet-1586	212	80	(	(	PUNCT
admet-1586	212	81	b	b	NOUN
admet-1586	212	82	)	)	PUNCT
admet-1586	212	83	420	420	NUM
admet-1586	212	84	-	-	PUNCT
admet-1586	212	85	480	480	NUM
admet-1586	212	86	min	min	NOUN
admet-1586	212	87	.	.	PUNCT
admet-1586	213	1	the	the	DET
admet-1586	213	2	error	error	NOUN
admet-1586	213	3	bars	bar	NOUN
admet-1586	213	4	represent	represent	VERB
admet-1586	213	5	the	the	DET
admet-1586	213	6	standard	standard	ADJ
admet-1586	213	7	deviation	deviation	NOUN
admet-1586	213	8	of	of	ADP
admet-1586	213	9	n	n	NOUN
admet-1586	213	10	=	=	SYM
admet-1586	213	11	3	3	X
admet-1586	213	12	.	.	PUNCT
admet-1586	213	13	conclusions	conclusion	NOUN
admet-1586	213	14	this	this	DET
admet-1586	213	15	study	study	NOUN
admet-1586	213	16	aimed	aim	VERB
admet-1586	213	17	to	to	PART
admet-1586	213	18	evaluate	evaluate	VERB
admet-1586	213	19	the	the	DET
admet-1586	213	20	potential	potential	NOUN
admet-1586	213	21	of	of	ADP
admet-1586	213	22	an	an	DET
admet-1586	213	23	experimental	experimental	ADJ
admet-1586	213	24	grade	grade	NOUN
admet-1586	213	25	of	of	ADP
admet-1586	213	26	hpmcas	hpmca	NOUN
admet-1586	213	27	-	-	PUNCT
admet-1586	213	28	mx	mx	NOUN
admet-1586	213	29	for	for	ADP
admet-1586	213	30	the	the	DET
admet-1586	213	31	processability	processability	NOUN
admet-1586	213	32	of	of	ADP
admet-1586	213	33	hot	hot	ADJ
admet-1586	213	34	-	-	PUNCT
admet-1586	213	35	melt	melt	NOUN
admet-1586	213	36	extrusion	extrusion	NOUN
admet-1586	213	37	and	and	CCONJ
admet-1586	213	38	improvement	improvement	NOUN
admet-1586	213	39	of	of	ADP
admet-1586	213	40	dissolution	dissolution	NOUN
admet-1586	213	41	-	-	PUNCT
admet-1586	213	42	permeation	permeation	NOUN
admet-1586	213	43	of	of	ADP
admet-1586	213	44	imc	imc	PROPN
admet-1586	213	45	as	as	ADP
admet-1586	213	46	a	a	DET
admet-1586	213	47	solid	solid	ADJ
admet-1586	213	48	dispersion	dispersion	NOUN
admet-1586	213	49	carrier	carrier	NOUN
admet-1586	213	50	compared	compare	VERB
admet-1586	213	51	to	to	ADP
admet-1586	213	52	a	a	DET
admet-1586	213	53	commercial	commercial	ADJ
admet-1586	213	54	grade	grade	NOUN
admet-1586	213	55	of	of	ADP
admet-1586	213	56	hpmcas	hpmca	NOUN
admet-1586	213	57	-	-	PUNCT
admet-1586	213	58	mg	mg	PROPN
admet-1586	213	59	.	.	PUNCT
admet-1586	214	1	monitoring	monitor	VERB
admet-1586	214	2	during	during	ADP
admet-1586	214	3	hot	hot	ADJ
admet-1586	214	4	-	-	PUNCT
admet-1586	214	5	melt	melt	NOUN
admet-1586	214	6	extrusion	extrusion	NOUN
admet-1586	214	7	revealed	reveal	VERB
admet-1586	214	8	that	that	SCONJ
admet-1586	214	9	torque	torque	NOUN
admet-1586	214	10	with	with	ADP
admet-1586	214	11	high	high	ADJ
admet-1586	214	12	-	-	PUNCT
admet-1586	214	13	share	share	NOUN
admet-1586	214	14	mixing	mixing	NOUN
admet-1586	214	15	was	be	AUX
admet-1586	214	16	reduced	reduce	VERB
admet-1586	214	17	depending	depend	VERB
admet-1586	214	18	on	on	ADP
admet-1586	214	19	the	the	DET
admet-1586	214	20	processing	processing	NOUN
admet-1586	214	21	time	time	NOUN
admet-1586	214	22	and	and	CCONJ
admet-1586	214	23	temperature	temperature	NOUN
admet-1586	214	24	.	.	PUNCT
admet-1586	215	1	the	the	DET
admet-1586	215	2	torque	torque	NOUN
admet-1586	215	3	of	of	ADP
admet-1586	215	4	imcmx	imcmx	NOUN
admet-1586	215	5	(	(	PUNCT
admet-1586	215	6	20:80	20:80	NUM
admet-1586	215	7	)	)	PUNCT
admet-1586	215	8	almost	almost	ADV
admet-1586	215	9	attained	attain	VERB
admet-1586	215	10	a	a	DET
admet-1586	215	11	plateau	plateau	NOUN
admet-1586	215	12	at	at	ADP
admet-1586	215	13	120	120	NUM
admet-1586	215	14	°	°	NOUN
admet-1586	215	15	c	c	NOUN
admet-1586	215	16	,	,	PUNCT
admet-1586	215	17	while	while	SCONJ
admet-1586	215	18	hpmcas	hpmca	NOUN
admet-1586	215	19	-	-	PUNCT
admet-1586	215	20	mg	mg	PROPN
admet-1586	215	21	(	(	PUNCT
admet-1586	215	22	20:80	20:80	NUM
admet-1586	215	23	)	)	PUNCT
admet-1586	215	24	did	do	VERB
admet-1586	215	25	not	not	PART
admet-1586	215	26	.	.	PUNCT
admet-1586	216	1	raman	raman	NOUN
admet-1586	216	2	mapping	mapping	NOUN
admet-1586	216	3	characterized	characterize	VERB
admet-1586	216	4	that	that	SCONJ
admet-1586	216	5	elevation	elevation	NOUN
admet-1586	216	6	of	of	ADP
admet-1586	216	7	the	the	DET
admet-1586	216	8	processing	processing	NOUN
admet-1586	216	9	temperature	temperature	NOUN
admet-1586	216	10	up	up	ADP
admet-1586	216	11	to	to	PART
admet-1586	216	12	170	170	NUM
admet-1586	216	13	°	°	NOUN
admet-1586	216	14	c	c	NOUN
admet-1586	216	15	induced	induce	VERB
admet-1586	216	16	transformation	transformation	NOUN
admet-1586	216	17	to	to	ADP
admet-1586	216	18	the	the	DET
admet-1586	216	19	solid	solid	ADJ
admet-1586	216	20	dispersions	dispersion	NOUN
admet-1586	216	21	for	for	ADP
admet-1586	216	22	both	both	DET
admet-1586	216	23	formulations	formulation	NOUN
admet-1586	216	24	.	.	PUNCT
admet-1586	217	1	these	these	DET
admet-1586	217	2	results	result	NOUN
admet-1586	217	3	show	show	VERB
admet-1586	217	4	that	that	SCONJ
admet-1586	217	5	the	the	DET
admet-1586	217	6	use	use	NOUN
admet-1586	217	7	of	of	ADP
admet-1586	217	8	hpmcas	hpmca	NOUN
admet-1586	217	9	-	-	PUNCT
admet-1586	217	10	mx	mx	NOUN
admet-1586	217	11	,	,	PUNCT
admet-1586	217	12	with	with	ADP
admet-1586	217	13	its	its	PRON
admet-1586	217	14	lower	low	ADJ
admet-1586	217	15	tg	tg	NOUN
admet-1586	217	16	,	,	PUNCT
admet-1586	217	17	enables	enable	VERB
admet-1586	217	18	the	the	DET
admet-1586	217	19	hot	hot	ADJ
admet-1586	217	20	-	-	PUNCT
admet-1586	217	21	melt	melt	NOUN
admet-1586	217	22	extrusion	extrusion	NOUN
admet-1586	217	23	process	process	NOUN
admet-1586	217	24	to	to	PART
admet-1586	217	25	be	be	AUX
admet-1586	217	26	conducted	conduct	VERB
admet-1586	217	27	at	at	ADP
admet-1586	217	28	a	a	DET
admet-1586	217	29	relatively	relatively	ADV
admet-1586	217	30	lower	low	ADJ
admet-1586	217	31	temperature	temperature	NOUN
admet-1586	217	32	.	.	PUNCT
admet-1586	218	1	the	the	DET
admet-1586	218	2	solid	solid	ADJ
admet-1586	218	3	dispersions	dispersion	NOUN
admet-1586	218	4	prepared	prepare	VERB
admet-1586	218	5	by	by	ADP
admet-1586	218	6	the	the	DET
admet-1586	218	7	hot	hot	ADJ
admet-1586	218	8	-	-	PUNCT
admet-1586	218	9	melt	melt	NOUN
admet-1586	218	10	extrusion	extrusion	NOUN
admet-1586	218	11	process	process	NOUN
admet-1586	218	12	showed	show	VERB
admet-1586	218	13	no	no	DET
admet-1586	218	14	crystallization	crystallization	NOUN
admet-1586	218	15	for	for	ADP
admet-1586	218	16	three	three	NUM
admet-1586	218	17	months	month	NOUN
admet-1586	218	18	at	at	ADP
admet-1586	218	19	40	40	NUM
admet-1586	218	20	°	°	NOUN
admet-1586	218	21	c	c	NOUN
admet-1586	218	22	.	.	PUNCT
admet-1586	219	1	the	the	DET
admet-1586	219	2	dissolution	dissolution	PROPN
admet-1586	219	3	test	test	NOUN
admet-1586	219	4	,	,	PUNCT
admet-1586	219	5	followed	follow	VERB
admet-1586	219	6	by	by	ADP
admet-1586	219	7	the	the	DET
admet-1586	219	8	permeation	permeation	NOUN
admet-1586	219	9	test	test	NOUN
admet-1586	219	10	by	by	ADP
admet-1586	219	11	simultaneous	simultaneous	ADJ
admet-1586	219	12	measurement	measurement	NOUN
admet-1586	219	13	of	of	ADP
admet-1586	219	14	the	the	DET
admet-1586	219	15	donor	donor	NOUN
admet-1586	219	16	and	and	CCONJ
admet-1586	219	17	acceptor	acceptor	NOUN
admet-1586	219	18	chambers	chamber	NOUN
admet-1586	219	19	,	,	PUNCT
admet-1586	219	20	showed	show	VERB
admet-1586	219	21	significant	significant	ADJ
admet-1586	219	22	enhancement	enhancement	NOUN
admet-1586	219	23	of	of	ADP
admet-1586	219	24	the	the	DET
admet-1586	219	25	dissolution	dissolution	NOUN
admet-1586	219	26	rate	rate	NOUN
admet-1586	219	27	and	and	CCONJ
admet-1586	219	28	dissolved	dissolve	VERB
admet-1586	219	29	amount	amount	NOUN
admet-1586	219	30	of	of	ADP
admet-1586	219	31	imc	imc	NOUN
admet-1586	219	32	for	for	ADP
admet-1586	219	33	both	both	CCONJ
admet-1586	219	34	the	the	DET
admet-1586	219	35	solid	solid	ADJ
admet-1586	219	36	dispersions	dispersion	NOUN
admet-1586	219	37	.	.	PUNCT
admet-1586	220	1	moreover	moreover	ADV
admet-1586	220	2	,	,	PUNCT
admet-1586	220	3	the	the	DET
admet-1586	220	4	flux	flux	NOUN
admet-1586	220	5	value	value	NOUN
admet-1586	220	6	of	of	ADP
admet-1586	220	7	imc	imc	PROPN
admet-1586	220	8	in	in	ADP
admet-1586	220	9	the	the	DET
admet-1586	220	10	solid	solid	ADJ
admet-1586	220	11	dispersion	dispersion	NOUN
admet-1586	220	12	was	be	AUX
admet-1586	220	13	higher	high	ADJ
admet-1586	220	14	than	than	ADP
admet-1586	220	15	that	that	PRON
admet-1586	220	16	of	of	ADP
admet-1586	220	17	crystalline	crystalline	PROPN
admet-1586	220	18	imc	imc	PROPN
admet-1586	220	19	,	,	PUNCT
admet-1586	220	20	reflecting	reflect	VERB
admet-1586	220	21	the	the	DET
admet-1586	220	22	improved	improved	ADJ
admet-1586	220	23	membrane	membrane	NOUN
admet-1586	220	24	penetration	penetration	NOUN
admet-1586	220	25	of	of	ADP
admet-1586	220	26	the	the	DET
admet-1586	220	27	solid	solid	ADJ
admet-1586	220	28	dispersions	dispersion	NOUN
admet-1586	220	29	.	.	PUNCT
admet-1586	221	1	therefore	therefore	ADV
admet-1586	221	2	,	,	PUNCT
admet-1586	221	3	it	it	PRON
admet-1586	221	4	is	be	AUX
admet-1586	221	5	concluded	conclude	VERB
admet-1586	221	6	that	that	SCONJ
admet-1586	221	7	hpmcas	hpmca	NOUN
admet-1586	221	8	-	-	PUNCT
admet-1586	221	9	mx	mx	PROPN
admet-1586	221	10	has	have	VERB
admet-1586	221	11	a	a	DET
admet-1586	221	12	comparable	comparable	ADJ
admet-1586	221	13	ability	ability	NOUN
admet-1586	221	14	to	to	ADP
admet-1586	221	15	the	the	DET
admet-1586	221	16	commercial	commercial	ADJ
admet-1586	221	17	grade	grade	NOUN
admet-1586	221	18	product	product	NOUN
admet-1586	221	19	as	as	ADP
admet-1586	221	20	a	a	DET
admet-1586	221	21	solid	solid	ADJ
admet-1586	221	22	dispersion	dispersion	NOUN
admet-1586	221	23	carrier	carrier	NOUN
admet-1586	221	24	for	for	ADP
admet-1586	221	25	both	both	CCONJ
admet-1586	221	26	solid	solid	ADJ
admet-1586	221	27	and	and	CCONJ
admet-1586	221	28	liquid	liquid	ADJ
admet-1586	221	29	phases	phase	NOUN
admet-1586	221	30	.	.	PUNCT
admet-1586	222	1	this	this	DET
admet-1586	222	2	study	study	NOUN
admet-1586	222	3	revealed	reveal	VERB
admet-1586	222	4	the	the	DET
admet-1586	222	5	applicability	applicability	NOUN
admet-1586	222	6	of	of	ADP
admet-1586	222	7	hpmcas	hpmcas	NOUN
admet-1586	222	8	-	-	PUNCT
admet-1586	222	9	mx	mx	NOUN
admet-1586	222	10	in	in	ADP
admet-1586	222	11	the	the	DET
admet-1586	222	12	hot	hot	ADJ
admet-1586	222	13	-	-	PUNCT
admet-1586	222	14	melt	melt	NOUN
admet-1586	222	15	extrusion	extrusion	NOUN
admet-1586	222	16	process	process	NOUN
admet-1586	222	17	.	.	PUNCT
admet-1586	223	1	further	further	ADJ
admet-1586	223	2	studies	study	NOUN
admet-1586	223	3	using	use	VERB
admet-1586	223	4	hpmcas	hpmca	NOUN
admet-1586	223	5	-	-	PUNCT
admet-1586	223	6	mx	mx	NOUN
admet-1586	223	7	should	should	AUX
admet-1586	223	8	be	be	AUX
admet-1586	223	9	conducted	conduct	VERB
admet-1586	223	10	to	to	PART
admet-1586	223	11	evaluate	evaluate	VERB
admet-1586	223	12	the	the	DET
admet-1586	223	13	effect	effect	NOUN
admet-1586	223	14	of	of	ADP
admet-1586	223	15	the	the	DET
admet-1586	223	16	processing	processing	NOUN
admet-1586	223	17	temperature	temperature	NOUN
admet-1586	223	18	on	on	ADP
admet-1586	223	19	the	the	DET
admet-1586	223	20	physicochemical	physicochemical	ADJ
admet-1586	223	21	properties	property	NOUN
admet-1586	223	22	of	of	ADP
admet-1586	223	23	the	the	DET
admet-1586	223	24	solid	solid	ADJ
admet-1586	223	25	dispersion	dispersion	NOUN
admet-1586	223	26	.	.	PUNCT
admet-1586	224	1	in	in	ADP
admet-1586	224	2	addition	addition	NOUN
admet-1586	224	3	,	,	PUNCT
admet-1586	224	4	they	they	PRON
admet-1586	224	5	should	should	AUX
admet-1586	224	6	investigate	investigate	VERB
admet-1586	224	7	the	the	DET
admet-1586	224	8	application	application	NOUN
admet-1586	224	9	of	of	ADP
admet-1586	224	10	our	our	PRON
admet-1586	224	11	findings	finding	NOUN
admet-1586	224	12	to	to	ADP
admet-1586	224	13	a	a	DET
admet-1586	224	14	drug	drug	NOUN
admet-1586	224	15	with	with	ADP
admet-1586	224	16	a	a	DET
admet-1586	224	17	high	high	ADJ
admet-1586	224	18	melting	melting	NOUN
admet-1586	224	19	temperature	temperature	NOUN
admet-1586	224	20	.	.	PUNCT
admet-1586	225	1	acknowledgments	acknowledgment	NOUN
admet-1586	225	2	:	:	PUNCT
admet-1586	225	3	we	we	PRON
admet-1586	225	4	would	would	AUX
admet-1586	225	5	like	like	VERB
admet-1586	225	6	to	to	PART
admet-1586	225	7	thank	thank	VERB
admet-1586	225	8	yoshiichiro	yoshiichiro	PROPN
admet-1586	225	9	aoyama	aoyama	NOUN
admet-1586	225	10	(	(	PUNCT
admet-1586	225	11	shin	shin	NOUN
admet-1586	225	12	-	-	PUNCT
admet-1586	225	13	etsu	etsu	PROPN
admet-1586	225	14	chemical	chemical	PROPN
admet-1586	225	15	co.	co.	PROPN
admet-1586	225	16	,	,	PUNCT
admet-1586	225	17	ltd	ltd	PROPN
admet-1586	225	18	.	.	PROPN
admet-1586	225	19	)	)	PUNCT
admet-1586	225	20	and	and	CCONJ
admet-1586	225	21	yasuyuki	yasuyuki	NOUN
admet-1586	225	22	hirama	hirama	NOUN
admet-1586	225	23	(	(	PUNCT
admet-1586	225	24	shin	shin	NOUN
admet-1586	225	25	-	-	PUNCT
admet-1586	225	26	etsu	etsu	PROPN
admet-1586	225	27	chemical	chemical	PROPN
admet-1586	225	28	co.	co.	PROPN
admet-1586	225	29	,	,	PUNCT
admet-1586	225	30	ltd	ltd	PROPN
admet-1586	225	31	.	.	PROPN
admet-1586	225	32	)	)	PUNCT
admet-1586	225	33	for	for	ADP
admet-1586	225	34	kindly	kindly	ADV
admet-1586	225	35	supplying	supply	VERB
admet-1586	225	36	hpmcas	hpmca	NOUN
admet-1586	225	37	-	-	PUNCT
admet-1586	225	38	mg	mg	PROPN
admet-1586	225	39	and	and	CCONJ
admet-1586	225	40	hpmcas	hpmca	NOUN
admet-1586	225	41	-	-	PUNCT
admet-1586	225	42	mx	mx	NOUN
admet-1586	225	43	and	and	CCONJ
admet-1586	225	44	providing	provide	VERB
admet-1586	225	45	information	information	NOUN
admet-1586	225	46	about	about	ADP
admet-1586	225	47	them	they	PRON
admet-1586	225	48	.	.	PUNCT
admet-1586	226	1	conflict	conflict	NOUN
admet-1586	226	2	of	of	ADP
admet-1586	226	3	interest	interest	NOUN
admet-1586	226	4	:	:	PUNCT
admet-1586	226	5	all	all	DET
admet-1586	226	6	authors	author	NOUN
admet-1586	226	7	are	be	AUX
admet-1586	226	8	employees	employee	NOUN
admet-1586	226	9	of	of	ADP
admet-1586	226	10	shionogi	shionogi	PROPN
admet-1586	226	11	&	&	CCONJ
admet-1586	226	12	co.	co.	PROPN
admet-1586	226	13	,	,	PUNCT
admet-1586	226	14	ltd	ltd	PROPN
admet-1586	226	15	.	.	PROPN
admet-1586	226	16	,	,	PUNCT
admet-1586	226	17	and	and	CCONJ
admet-1586	226	18	there	there	PRON
admet-1586	226	19	is	be	VERB
admet-1586	226	20	no	no	DET
admet-1586	226	21	competing	compete	VERB
admet-1586	226	22	interest	interest	NOUN
admet-1586	226	23	.	.	PUNCT
admet-1586	227	1	references	reference	NOUN
admet-1586	227	2	[	[	X
admet-1586	227	3	1	1	NUM
admet-1586	227	4	]	]	X
admet-1586	227	5	j.d	j.d	PROPN
admet-1586	227	6	.	.	PROPN
admet-1586	227	7	bucheit	bucheit	PROPN
admet-1586	227	8	,	,	PUNCT
admet-1586	227	9	l.g	l.g	PROPN
admet-1586	227	10	.	.	PROPN
admet-1586	227	11	pamulapati	pamulapati	PROPN
admet-1586	227	12	,	,	PUNCT
admet-1586	227	13	n.	n.	PROPN
admet-1586	227	14	carter	carter	PROPN
admet-1586	227	15	,	,	PUNCT
admet-1586	227	16	k.	k.	PROPN
admet-1586	227	17	malloy	malloy	PROPN
admet-1586	227	18	,	,	PUNCT
admet-1586	227	19	d.l	d.l	PROPN
admet-1586	227	20	.	.	PROPN
admet-1586	227	21	dixon	dixon	PROPN
admet-1586	227	22	,	,	PUNCT
admet-1586	227	23	e.m	e.m	PROPN
admet-1586	227	24	.	.	PROPN
admet-1586	227	25	sisson	sisson	PROPN
admet-1586	227	26	.	.	PUNCT
admet-1586	228	1	oral	oral	ADJ
admet-1586	228	2	semaglutide	semaglutide	NOUN
admet-1586	228	3	:	:	PUNCT
admet-1586	228	4	a	a	DET
admet-1586	228	5	review	review	NOUN
admet-1586	228	6	of	of	ADP
admet-1586	228	7	the	the	DET
admet-1586	228	8	first	first	ADJ
admet-1586	228	9	oral	oral	ADJ
admet-1586	228	10	glucagon	glucagon	NOUN
admet-1586	228	11	-	-	PUNCT
admet-1586	228	12	like	like	ADJ
admet-1586	228	13	peptide	peptide	NOUN
admet-1586	228	14	1	1	NUM
admet-1586	228	15	receptor	receptor	NOUN
admet-1586	228	16	agonist	agonist	NOUN
admet-1586	228	17	.	.	PUNCT
admet-1586	229	1	diabetes	diabetes	NOUN
admet-1586	229	2	technology	technology	NOUN
admet-1586	229	3	and	and	CCONJ
admet-1586	229	4	therapeutics	therapeutic	NOUN
admet-1586	229	5	22	22	NUM
admet-1586	229	6	(	(	PUNCT
admet-1586	229	7	2020	2020	NUM
admet-1586	229	8	)	)	PUNCT
admet-1586	229	9	10	10	NUM
admet-1586	229	10	-	-	SYM
admet-1586	229	11	18	18	NUM
admet-1586	229	12	.	.	PUNCT
admet-1586	230	1	http://doi.org/10.1089/dia.2019.0185	http://doi.org/10.1089/dia.2019.0185	NOUN
admet-1586	230	2	.	.	PUNCT
admet-1586	231	1	[	[	X
admet-1586	231	2	2	2	NUM
admet-1586	231	3	]	]	X
admet-1586	231	4	p.g	p.g	PROPN
admet-1586	231	5	.	.	PROPN
admet-1586	231	6	dougherty	dougherty	PROPN
admet-1586	231	7	,	,	PUNCT
admet-1586	231	8	a.	a.	PROPN
admet-1586	231	9	sahni	sahni	PROPN
admet-1586	231	10	,	,	PUNCT
admet-1586	231	11	d.	d.	PROPN
admet-1586	231	12	pei	pei	PROPN
admet-1586	231	13	.	.	PUNCT
admet-1586	232	1	understanding	understand	VERB
admet-1586	232	2	cell	cell	NOUN
admet-1586	232	3	penetration	penetration	NOUN
admet-1586	232	4	of	of	ADP
admet-1586	232	5	cyclic	cyclic	ADJ
admet-1586	232	6	peptides	peptide	NOUN
admet-1586	232	7	.	.	PUNCT
admet-1586	233	1	chemical	chemical	ADJ
admet-1586	233	2	reviews	review	NOUN
admet-1586	233	3	119	119	NUM
admet-1586	233	4	(	(	PUNCT
admet-1586	233	5	2019	2019	NUM
admet-1586	233	6	)	)	PUNCT
admet-1586	233	7	10241	10241	NUM
admet-1586	233	8	-	-	SYM
admet-1586	233	9	10287	10287	NUM
admet-1586	233	10	.	.	PUNCT
admet-1586	234	1	https://doi.org/10.1021/acs.chemrev.9b00008	https://doi.org/10.1021/acs.chemrev.9b00008	NOUN
admet-1586	234	2	.	.	PUNCT
admet-1586	235	1	p	p	X
admet-1586	235	2	e	e	PROPN
admet-1586	235	3	rm	rm	PROPN
admet-1586	235	4	e	e	PROPN
admet-1586	235	5	a	a	PROPN
admet-1586	235	6	te	te	PROPN
admet-1586	235	7	d	d	X
admet-1586	235	8	(	(	PUNCT
admet-1586	235	9	µ	µ	PRON
admet-1586	235	10	g	g	NOUN
admet-1586	235	11	/m	/m	SYM
admet-1586	235	12	l	l	NOUN
admet-1586	235	13	)	)	PUNCT
admet-1586	235	14	time	time	NOUN
admet-1586	235	15	(	(	PUNCT
admet-1586	235	16	min	min	NOUN
admet-1586	235	17	)	)	PUNCT
admet-1586	235	18	0	0	NUM
admet-1586	235	19	480120	480120	NUM
admet-1586	236	1	360	360	NUM
admet-1586	236	2	000	000	NUM
admet-1586	236	3	020	020	NUM
admet-1586	236	4	060	060	NUM
admet-1586	236	5	100	100	NUM
admet-1586	236	6	040	040	NUM
admet-1586	236	7	080	080	NUM
admet-1586	236	8	240	240	NUM
admet-1586	236	9	●	●	NUM
admet-1586	236	10	imc	imc	PROPN
admet-1586	236	11	-	-	PUNCT
admet-1586	236	12	mg	mg	PROPN
admet-1586	236	13	(	(	PUNCT
admet-1586	236	14	20:80	20:80	NUM
admet-1586	236	15	)	)	PUNCT
admet-1586	236	16	●	●	PUNCT
admet-1586	236	17	imc	imc	PROPN
admet-1586	236	18	-	-	PUNCT
admet-1586	236	19	mx	mx	PROPN
admet-1586	236	20	(	(	PUNCT
admet-1586	236	21	20:80	20:80	NUM
admet-1586	236	22	)	)	PUNCT
admet-1586	236	23	●	●	NUM
admet-1586	236	24	crystalline	crystalline	NOUN
admet-1586	236	25	imc	imc	NOUN
admet-1586	236	26	y	y	PROPN
admet-1586	236	27	=	=	PUNCT
admet-1586	236	28	0.2001x	0.2001x	NOUN
admet-1586	236	29	16.405	16.405	NUM
admet-1586	236	30	r²	r²	NOUN
admet-1586	236	31	=	=	PUNCT
admet-1586	236	32	0.9992	0.9992	NUM
admet-1586	236	33	y	y	NOUN
admet-1586	236	34	=	=	PUNCT
admet-1586	236	35	0.2083x	0.2083x	ADJ
admet-1586	236	36	16.88	16.88	NUM
admet-1586	236	37	r²	r²	NOUN
admet-1586	236	38	=	=	SYM
admet-1586	236	39	0.9989	0.9989	NUM
admet-1586	236	40	y	y	NOUN
admet-1586	236	41	=	=	PUNCT
admet-1586	236	42	0.1062x	0.1062x	NUM
admet-1586	236	43	9.3842	9.3842	NUM
admet-1586	236	44	r²	r²	NOUN
admet-1586	236	45	=	=	SYM
admet-1586	236	46	0.9957p	0.9957p	PROPN
admet-1586	236	47	e	e	PROPN
admet-1586	236	48	rm	rm	PROPN
admet-1586	236	49	e	e	PROPN
admet-1586	236	50	a	a	PROPN
admet-1586	236	51	te	te	PROPN
admet-1586	236	52	d	d	X
admet-1586	236	53	(	(	PUNCT
admet-1586	236	54	µ	µ	PRON
admet-1586	236	55	g	g	NOUN
admet-1586	236	56	/m	/m	SYM
admet-1586	236	57	l	l	NOUN
admet-1586	236	58	)	)	PUNCT
admet-1586	236	59	time	time	NOUN
admet-1586	236	60	(	(	PUNCT
admet-1586	236	61	min	min	NOUN
admet-1586	236	62	)	)	PUNCT
admet-1586	236	63	420	420	NUM
admet-1586	236	64	480435	480435	NUM
admet-1586	236	65	465	465	NUM
admet-1586	236	66	000	000	NUM
admet-1586	236	67	020	020	NUM
admet-1586	236	68	060	060	NUM
admet-1586	236	69	100	100	NUM
admet-1586	236	70	040	040	NUM
admet-1586	236	71	080	080	NUM
admet-1586	236	72	450	450	NUM
admet-1586	236	73	●	●	NUM
admet-1586	236	74	imc	imc	NOUN
admet-1586	236	75	-	-	PUNCT
admet-1586	236	76	mg	mg	PROPN
admet-1586	236	77	(	(	PUNCT
admet-1586	236	78	20:80	20:80	NUM
admet-1586	236	79	)	)	PUNCT
admet-1586	236	80	●	●	PUNCT
admet-1586	236	81	imc	imc	PROPN
admet-1586	236	82	-	-	PUNCT
admet-1586	236	83	mx	mx	PROPN
admet-1586	236	84	(	(	PUNCT
admet-1586	236	85	20:80	20:80	NUM
admet-1586	236	86	)	)	PUNCT
admet-1586	236	87	●	●	NUM
admet-1586	236	88	crystalline	crystalline	NOUN
admet-1586	236	89	imcp	imcp	NOUN
admet-1586	236	90	er	er	INTJ
admet-1586	236	91	m	m	NOUN
admet-1586	236	92	ea	ea	NOUN
admet-1586	236	93	te	te	PROPN
admet-1586	236	94	d	d	X
admet-1586	236	95	a	a	DET
admet-1586	236	96	m	m	NOUN
admet-1586	236	97	o	o	NOUN
admet-1586	236	98	u	u	NOUN
admet-1586	236	99	n	n	PRON
admet-1586	236	100	t	t	PROPN
admet-1586	236	101	,	,	PUNCT
admet-1586	236	102	m	m	VERB
admet-1586	236	103	g	g	NOUN
admet-1586	236	104	m	m	PROPN
admet-1586	236	105	l-1	l-1	NOUN
admet-1586	236	106	p	p	X
admet-1586	236	107	er	er	INTJ
admet-1586	236	108	m	m	NOUN
admet-1586	236	109	ea	ea	NOUN
admet-1586	236	110	te	te	PROPN
admet-1586	236	111	d	d	X
admet-1586	236	112	a	a	DET
admet-1586	236	113	m	m	NOUN
admet-1586	236	114	o	o	NOUN
admet-1586	236	115	u	u	NOUN
admet-1586	236	116	n	n	PRON
admet-1586	236	117	t	t	PROPN
admet-1586	236	118	,	,	PUNCT
admet-1586	236	119	m	m	VERB
admet-1586	236	120	g	g	NOUN
admet-1586	236	121	m	m	PROPN
admet-1586	236	122	l-1	l-1	NOUN
admet-1586	236	123	http://doi.org/10.1089/dia.2019.0185	http://doi.org/10.1089/dia.2019.0185	PROPN
admet-1586	236	124	https://doi.org/10.1021/acs.chemrev.9b00008	https://doi.org/10.1021/acs.chemrev.9b00008	PROPN
admet-1586	236	125	admet	admet	PROPN
admet-1586	236	126	&	&	CCONJ
admet-1586	236	127	dmpk	dmpk	PROPN
admet-1586	236	128	11(3	11(3	NUM
admet-1586	236	129	)	)	PUNCT
admet-1586	236	130	(	(	PUNCT
admet-1586	236	131	2023	2023	NUM
admet-1586	236	132	)	)	PUNCT
admet-1586	236	133	373	373	NUM
admet-1586	236	134	-	-	SYM
admet-1586	236	135	385	385	NUM
admet-1586	236	136	dissolution	dissolution	NOUN
admet-1586	236	137	-	-	PUNCT
admet-1586	236	138	permeation	permeation	NOUN
admet-1586	236	139	of	of	ADP
admet-1586	236	140	hot	hot	ADJ
admet-1586	236	141	-	-	PUNCT
admet-1586	236	142	melt	melt	NOUN
admet-1586	236	143	extruded	extrude	VERB
admet-1586	236	144	asd	asd	NOUN
admet-1586	236	145	doi	doi	PROPN
admet-1586	236	146	:	:	PUNCT
admet-1586	236	147	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	NOUN
admet-1586	236	148	383	383	NUM
admet-1586	236	149	[	[	X
admet-1586	236	150	3	3	NUM
admet-1586	236	151	]	]	X
admet-1586	236	152	j.	j.	PROPN
admet-1586	236	153	han	han	PROPN
admet-1586	236	154	,	,	PUNCT
admet-1586	236	155	y.	y.	PROPN
admet-1586	236	156	wei	wei	PROPN
admet-1586	236	157	,	,	PUNCT
admet-1586	236	158	y.	y.	PROPN
admet-1586	236	159	lu	lu	PROPN
admet-1586	236	160	,	,	PUNCT
admet-1586	236	161	r.	r.	PROPN
admet-1586	236	162	wang	wang	PROPN
admet-1586	236	163	,	,	PUNCT
admet-1586	236	164	j.	j.	PROPN
admet-1586	236	165	zhang	zhang	PROPN
admet-1586	236	166	,	,	PUNCT
admet-1586	236	167	y.	y.	PROPN
admet-1586	236	168	gao	gao	PROPN
admet-1586	236	169	,	,	PUNCT
admet-1586	236	170	s.	s.	PROPN
admet-1586	236	171	qian	qian	PROPN
admet-1586	236	172	.	.	PUNCT
admet-1586	237	1	co	co	VERB
admet-1586	237	2	-	-	ADJ
admet-1586	237	3	amorphous	amorphous	ADJ
admet-1586	237	4	systems	system	NOUN
admet-1586	237	5	for	for	ADP
admet-1586	237	6	the	the	DET
admet-1586	237	7	delivery	delivery	NOUN
admet-1586	237	8	of	of	ADP
admet-1586	237	9	poorly	poorly	ADV
admet-1586	237	10	water	water	NOUN
admet-1586	237	11	-	-	PUNCT
admet-1586	237	12	soluble	soluble	ADJ
admet-1586	237	13	drugs	drug	NOUN
admet-1586	237	14	:	:	PUNCT
admet-1586	237	15	recent	recent	ADJ
admet-1586	237	16	advances	advance	NOUN
admet-1586	237	17	and	and	CCONJ
admet-1586	237	18	an	an	DET
admet-1586	237	19	update	update	NOUN
admet-1586	237	20	.	.	PUNCT
admet-1586	238	1	expert	expert	ADJ
admet-1586	238	2	opinion	opinion	NOUN
admet-1586	238	3	on	on	ADP
admet-1586	238	4	drug	drug	NOUN
admet-1586	238	5	delivery	delivery	NOUN
admet-1586	238	6	17	17	NUM
admet-1586	238	7	(	(	PUNCT
admet-1586	238	8	2020	2020	NUM
admet-1586	238	9	)	)	PUNCT
admet-1586	238	10	1411	1411	NUM
admet-1586	238	11	-	-	SYM
admet-1586	238	12	1435	1435	NUM
admet-1586	238	13	.	.	PUNCT
admet-1586	239	1	https://doi.org/10.1080/17425247.2020.1796631	https://doi.org/10.1080/17425247.2020.1796631	X
admet-1586	239	2	.	.	PUNCT
admet-1586	240	1	[	[	X
admet-1586	240	2	4	4	X
admet-1586	240	3	]	]	X
admet-1586	240	4	h.d	h.d	PROPN
admet-1586	240	5	.	.	PROPN
admet-1586	240	6	williams	williams	PROPN
admet-1586	240	7	,	,	PUNCT
admet-1586	240	8	n.l	n.l	PROPN
admet-1586	240	9	.	.	PROPN
admet-1586	240	10	trevaskis	trevaskis	PROPN
admet-1586	240	11	,	,	PUNCT
admet-1586	240	12	s.a	s.a	PROPN
admet-1586	240	13	.	.	PROPN
admet-1586	240	14	charman	charman	PROPN
admet-1586	240	15	,	,	PUNCT
admet-1586	240	16	r.m	r.m	PROPN
admet-1586	240	17	.	.	PROPN
admet-1586	240	18	shanker	shanker	PROPN
admet-1586	240	19	,	,	PUNCT
admet-1586	240	20	w.n	w.n	PROPN
admet-1586	240	21	.	.	PROPN
admet-1586	240	22	charman	charman	PROPN
admet-1586	240	23	,	,	PUNCT
admet-1586	240	24	c.w	c.w	PROPN
admet-1586	240	25	.	.	PROPN
admet-1586	240	26	pouton	pouton	PROPN
admet-1586	240	27	,	,	PUNCT
admet-1586	240	28	c.j	c.j	PROPN
admet-1586	240	29	.	.	PROPN
admet-1586	240	30	porter	porter	NOUN
admet-1586	240	31	.	.	PUNCT
admet-1586	241	1	strategies	strategy	NOUN
admet-1586	241	2	to	to	PART
admet-1586	241	3	address	address	VERB
admet-1586	241	4	low	low	ADJ
admet-1586	241	5	drug	drug	NOUN
admet-1586	241	6	solubility	solubility	NOUN
admet-1586	241	7	in	in	ADP
admet-1586	241	8	discovery	discovery	NOUN
admet-1586	241	9	and	and	CCONJ
admet-1586	241	10	development	development	NOUN
admet-1586	241	11	.	.	PUNCT
admet-1586	242	1	pharmacological	pharmacological	ADJ
admet-1586	242	2	reviews	review	NOUN
admet-1586	242	3	65	65	NUM
admet-1586	242	4	(	(	PUNCT
admet-1586	242	5	2013	2013	NUM
admet-1586	242	6	)	)	PUNCT
admet-1586	242	7	315	315	NUM
admet-1586	242	8	-	-	SYM
admet-1586	242	9	499	499	NUM
admet-1586	242	10	.	.	PUNCT
admet-1586	242	11	https://doi.org/10.1124/pr.112.005660	https://doi.org/10.1124/pr.112.005660	NOUN
admet-1586	242	12	.	.	PUNCT
admet-1586	243	1	[	[	X
admet-1586	243	2	5	5	NUM
admet-1586	243	3	]	]	PUNCT
admet-1586	243	4	p.	p.	NOUN
admet-1586	243	5	pandi	pandi	PROPN
admet-1586	243	6	,	,	PUNCT
admet-1586	243	7	r.	r.	PROPN
admet-1586	243	8	bulusu	bulusu	PROPN
admet-1586	243	9	,	,	PUNCT
admet-1586	243	10	n.	n.	PROPN
admet-1586	243	11	kommineni	kommineni	PROPN
admet-1586	243	12	,	,	PUNCT
admet-1586	243	13	w.	w.	PROPN
admet-1586	243	14	khan	khan	PROPN
admet-1586	243	15	,	,	PUNCT
admet-1586	243	16	m.	m.	NOUN
admet-1586	243	17	singh	singh	PROPN
admet-1586	243	18	.	.	PUNCT
admet-1586	244	1	amorphous	amorphous	ADJ
admet-1586	244	2	solid	solid	ADJ
admet-1586	244	3	dispersions	dispersion	NOUN
admet-1586	244	4	:	:	PUNCT
admet-1586	244	5	an	an	DET
admet-1586	244	6	update	update	NOUN
admet-1586	244	7	for	for	ADP
admet-1586	244	8	preparation	preparation	NOUN
admet-1586	244	9	,	,	PUNCT
admet-1586	244	10	characterization	characterization	NOUN
admet-1586	244	11	,	,	PUNCT
admet-1586	244	12	mechanism	mechanism	NOUN
admet-1586	244	13	on	on	ADP
admet-1586	244	14	bioavailability	bioavailability	NOUN
admet-1586	244	15	,	,	PUNCT
admet-1586	244	16	stability	stability	NOUN
admet-1586	244	17	,	,	PUNCT
admet-1586	244	18	regulatory	regulatory	ADJ
admet-1586	244	19	considerations	consideration	NOUN
admet-1586	244	20	and	and	CCONJ
admet-1586	244	21	marketed	market	VERB
admet-1586	244	22	products	product	NOUN
admet-1586	244	23	.	.	PUNCT
admet-1586	245	1	international	international	ADJ
admet-1586	245	2	journal	journal	PROPN
admet-1586	245	3	of	of	ADP
admet-1586	245	4	pharmaceutics	pharmaceutic	NOUN
admet-1586	245	5	586	586	NUM
admet-1586	245	6	(	(	PUNCT
admet-1586	245	7	2020	2020	NUM
admet-1586	245	8	)	)	PUNCT
admet-1586	245	9	119560	119560	NUM
admet-1586	245	10	.	.	PUNCT
admet-1586	246	1	https://doi.org/10.1016/j.ijpharm.2020.119560	https://doi.org/10.1016/j.ijpharm.2020.119560	ADJ
admet-1586	246	2	.	.	PUNCT
admet-1586	247	1	[	[	X
admet-1586	247	2	6	6	NUM
admet-1586	247	3	]	]	PUNCT
admet-1586	247	4	s.	s.	PROPN
admet-1586	247	5	alshehri	alshehri	PROPN
admet-1586	247	6	,	,	PUNCT
admet-1586	247	7	s.s	s.s	PROPN
admet-1586	247	8	.	.	PROPN
admet-1586	247	9	imam	imam	PROPN
admet-1586	247	10	,	,	PUNCT
admet-1586	247	11	a.	a.	NOUN
admet-1586	247	12	hussain	hussain	PROPN
admet-1586	247	13	,	,	PUNCT
admet-1586	247	14	m.a	m.a	PROPN
admet-1586	247	15	.	.	PROPN
admet-1586	247	16	altamimi	altamimi	PROPN
admet-1586	247	17	,	,	PUNCT
admet-1586	247	18	n.k	n.k	PROPN
admet-1586	247	19	.	.	NOUN
admet-1586	247	20	alruwaili	alruwaili	NOUN
admet-1586	247	21	,	,	PUNCT
admet-1586	247	22	f.	f.	PROPN
admet-1586	247	23	alotaibi	alotaibi	PROPN
admet-1586	247	24	,	,	PUNCT
admet-1586	247	25	a.	a.	NOUN
admet-1586	247	26	alanazi	alanazi	PROPN
admet-1586	247	27	,	,	PUNCT
admet-1586	247	28	f.	f.	PROPN
admet-1586	247	29	shakeel	shakeel	PROPN
admet-1586	247	30	.	.	PUNCT
admet-1586	248	1	potential	potential	NOUN
admet-1586	248	2	of	of	ADP
admet-1586	248	3	solid	solid	ADJ
admet-1586	248	4	dispersions	dispersion	NOUN
admet-1586	248	5	to	to	PART
admet-1586	248	6	enhance	enhance	VERB
admet-1586	248	7	solubility	solubility	NOUN
admet-1586	248	8	,	,	PUNCT
admet-1586	248	9	bioavailability	bioavailability	NOUN
admet-1586	248	10	,	,	PUNCT
admet-1586	248	11	and	and	CCONJ
admet-1586	248	12	therapeutic	therapeutic	ADJ
admet-1586	248	13	efficacy	efficacy	NOUN
admet-1586	248	14	of	of	ADP
admet-1586	248	15	poorly	poorly	ADV
admet-1586	248	16	water	water	NOUN
admet-1586	248	17	-	-	PUNCT
admet-1586	248	18	soluble	soluble	ADJ
admet-1586	248	19	drugs	drug	NOUN
admet-1586	248	20	:	:	PUNCT
admet-1586	248	21	newer	new	ADJ
admet-1586	248	22	formulation	formulation	NOUN
admet-1586	248	23	techniques	technique	NOUN
admet-1586	248	24	,	,	PUNCT
admet-1586	248	25	current	current	ADJ
admet-1586	248	26	marketed	market	VERB
admet-1586	248	27	scenario	scenario	NOUN
admet-1586	248	28	and	and	CCONJ
admet-1586	248	29	patents	patent	NOUN
admet-1586	248	30	.	.	PUNCT
admet-1586	249	1	drug	drug	NOUN
admet-1586	249	2	delivery	delivery	NOUN
admet-1586	249	3	27	27	NUM
admet-1586	249	4	(	(	PUNCT
admet-1586	249	5	2020	2020	NUM
admet-1586	249	6	)	)	PUNCT
admet-1586	249	7	1625	1625	NUM
admet-1586	249	8	-	-	SYM
admet-1586	249	9	1643	1643	NUM
admet-1586	249	10	.	.	PUNCT
admet-1586	250	1	https://doi.org/10.1080/10717544.2020.1846638	https://doi.org/10.1080/10717544.2020.1846638	PROPN
admet-1586	250	2	.	.	PUNCT
admet-1586	251	1	[	[	X
admet-1586	251	2	7	7	NUM
admet-1586	251	3	]	]	SYM
admet-1586	251	4	a.b	a.b	PROPN
admet-1586	251	5	.	.	PROPN
admet-1586	251	6	anane	anane	PROPN
admet-1586	251	7	-	-	PUNCT
admet-1586	251	8	adjei	adjei	PROPN
admet-1586	251	9	,	,	PUNCT
admet-1586	251	10	e.	e.	PROPN
admet-1586	251	11	jacobs	jacobs	PROPN
admet-1586	251	12	,	,	PUNCT
admet-1586	251	13	s.c	s.c	PROPN
admet-1586	251	14	.	.	PROPN
admet-1586	251	15	nash	nash	PROPN
admet-1586	251	16	,	,	PUNCT
admet-1586	251	17	s.	s.	PROPN
admet-1586	251	18	askin	askin	PROPN
admet-1586	251	19	,	,	PUNCT
admet-1586	251	20	r.	r.	PROPN
admet-1586	251	21	soundararajan	soundararajan	PROPN
admet-1586	251	22	,	,	PUNCT
admet-1586	251	23	m.	m.	NOUN
admet-1586	251	24	kyobula	kyobula	PROPN
admet-1586	251	25	,	,	PUNCT
admet-1586	251	26	j.	j.	PROPN
admet-1586	251	27	booth	booth	PROPN
admet-1586	251	28	,	,	PUNCT
admet-1586	251	29	a.	a.	PROPN
admet-1586	251	30	campbell	campbell	PROPN
admet-1586	251	31	.	.	PUNCT
admet-1586	252	1	amorphous	amorphous	ADJ
admet-1586	252	2	solid	solid	ADJ
admet-1586	252	3	dispersions	dispersion	NOUN
admet-1586	252	4	:	:	PUNCT
admet-1586	252	5	utilization	utilization	NOUN
admet-1586	252	6	and	and	CCONJ
admet-1586	252	7	challenges	challenge	NOUN
admet-1586	252	8	in	in	ADP
admet-1586	252	9	preclinical	preclinical	ADJ
admet-1586	252	10	drug	drug	NOUN
admet-1586	252	11	development	development	NOUN
admet-1586	252	12	within	within	ADP
admet-1586	252	13	astrazeneca	astrazeneca	PROPN
admet-1586	252	14	.	.	PUNCT
admet-1586	253	1	international	international	PROPN
admet-1586	253	2	journal	journal	PROPN
admet-1586	253	3	of	of	ADP
admet-1586	253	4	pharmaceutics	pharmaceutic	NOUN
admet-1586	253	5	614	614	NUM
admet-1586	253	6	(	(	PUNCT
admet-1586	253	7	2022	2022	NUM
admet-1586	253	8	)	)	PUNCT
admet-1586	253	9	121387	121387	NUM
admet-1586	253	10	.	.	PUNCT
admet-1586	254	1	https://doi.org/10.1016/j.ijpharm.2021.121387	https://doi.org/10.1016/j.ijpharm.2021.121387	NOUN
admet-1586	254	2	.	.	PUNCT
admet-1586	255	1	[	[	X
admet-1586	255	2	8	8	NUM
admet-1586	255	3	]	]	X
admet-1586	255	4	m.f	m.f	PROPN
admet-1586	255	5	.	.	PROPN
admet-1586	255	6	simões	simões	PROPN
admet-1586	255	7	,	,	PUNCT
admet-1586	255	8	r.m.a	r.m.a	NOUN
admet-1586	255	9	.	.	PUNCT
admet-1586	255	10	pinto	pinto	PROPN
admet-1586	255	11	,	,	PUNCT
admet-1586	255	12	s.	s.	PROPN
admet-1586	255	13	simões	simões	PROPN
admet-1586	255	14	.	.	PUNCT
admet-1586	256	1	hot	hot	ADJ
admet-1586	256	2	-	-	PUNCT
admet-1586	256	3	melt	melt	NOUN
admet-1586	256	4	extrusion	extrusion	NOUN
admet-1586	256	5	in	in	ADP
admet-1586	256	6	the	the	DET
admet-1586	256	7	pharmaceutical	pharmaceutical	ADJ
admet-1586	256	8	industry	industry	NOUN
admet-1586	256	9	:	:	PUNCT
admet-1586	256	10	toward	toward	ADP
admet-1586	256	11	filing	file	VERB
admet-1586	256	12	a	a	DET
admet-1586	256	13	new	new	ADJ
admet-1586	256	14	drug	drug	NOUN
admet-1586	256	15	application	application	NOUN
admet-1586	256	16	.	.	PUNCT
admet-1586	257	1	drug	drug	NOUN
admet-1586	257	2	discovery	discovery	PROPN
admet-1586	257	3	today	today	NOUN
admet-1586	257	4	24	24	NUM
admet-1586	257	5	(	(	PUNCT
admet-1586	257	6	2019	2019	NUM
admet-1586	257	7	)	)	PUNCT
admet-1586	257	8	1749	1749	NUM
admet-1586	257	9	-	-	SYM
admet-1586	257	10	1768	1768	NUM
admet-1586	257	11	.	.	PUNCT
admet-1586	258	1	https://doi.org/10.1016/j.drudis.2019.05.013	https://doi.org/10.1016/j.drudis.2019.05.013	NUM
admet-1586	258	2	.	.	PUNCT
admet-1586	259	1	[	[	X
admet-1586	259	2	9	9	NUM
admet-1586	259	3	]	]	X
admet-1586	259	4	n.	n.	NOUN
admet-1586	259	5	mendonsa	mendonsa	PROPN
admet-1586	259	6	,	,	PUNCT
admet-1586	259	7	b.	b.	PROPN
admet-1586	259	8	almutairy	almutairy	PROPN
admet-1586	259	9	,	,	PUNCT
admet-1586	259	10	v.r	v.r	PROPN
admet-1586	259	11	.	.	PROPN
admet-1586	259	12	kallakunta	kallakunta	PROPN
admet-1586	259	13	,	,	PUNCT
admet-1586	259	14	s.	s.	PROPN
admet-1586	259	15	sarabu	sarabu	PROPN
admet-1586	259	16	,	,	PUNCT
admet-1586	259	17	p.	p.	PROPN
admet-1586	259	18	thipsay	thipsay	PROPN
admet-1586	259	19	,	,	PUNCT
admet-1586	259	20	s.	s.	PROPN
admet-1586	259	21	bandari	bandari	PROPN
admet-1586	259	22	,	,	PUNCT
admet-1586	259	23	m.a	m.a	PROPN
admet-1586	259	24	.	.	PROPN
admet-1586	259	25	repka	repka	PROPN
admet-1586	259	26	.	.	PUNCT
admet-1586	260	1	manufacturing	manufacture	VERB
admet-1586	260	2	strategies	strategy	NOUN
admet-1586	260	3	to	to	PART
admet-1586	260	4	develop	develop	VERB
admet-1586	260	5	amorphous	amorphous	ADJ
admet-1586	260	6	solid	solid	ADJ
admet-1586	260	7	dispersions	dispersion	NOUN
admet-1586	260	8	:	:	PUNCT
admet-1586	260	9	an	an	DET
admet-1586	260	10	overview	overview	NOUN
admet-1586	260	11	.	.	PUNCT
admet-1586	261	1	journal	journal	NOUN
admet-1586	261	2	of	of	ADP
admet-1586	261	3	drug	drug	NOUN
admet-1586	261	4	delivery	delivery	NOUN
admet-1586	261	5	science	science	NOUN
admet-1586	261	6	and	and	CCONJ
admet-1586	261	7	technology	technology	NOUN
admet-1586	261	8	55	55	NUM
admet-1586	261	9	(	(	PUNCT
admet-1586	261	10	2020	2020	NUM
admet-1586	261	11	)	)	PUNCT
admet-1586	261	12	101459	101459	NUM
admet-1586	261	13	.	.	PUNCT
admet-1586	262	1	https://doi.org/10.1016/j.jddst.2019.101459	https://doi.org/10.1016/j.jddst.2019.101459	NOUN
admet-1586	262	2	.	.	PUNCT
admet-1586	263	1	[	[	X
admet-1586	263	2	10	10	NUM
admet-1586	263	3	]	]	X
admet-1586	263	4	a.t.m	a.t.m	X
admet-1586	263	5	.	.	PUNCT
admet-1586	264	1	serajuddin	serajuddin	VERB
admet-1586	264	2	.	.	PUNCT
admet-1586	265	1	challenges	challenge	NOUN
admet-1586	265	2	,	,	PUNCT
admet-1586	265	3	current	current	ADJ
admet-1586	265	4	status	status	NOUN
admet-1586	265	5	and	and	CCONJ
admet-1586	265	6	emerging	emerge	VERB
admet-1586	265	7	strategies	strategy	NOUN
admet-1586	265	8	in	in	ADP
admet-1586	265	9	the	the	DET
admet-1586	265	10	development	development	NOUN
admet-1586	265	11	of	of	ADP
admet-1586	265	12	rapidly	rapidly	ADV
admet-1586	265	13	dissolving	dissolve	VERB
admet-1586	265	14	fdm	fdm	NOUN
admet-1586	265	15	3d	3d	ADV
admet-1586	265	16	-	-	PUNCT
admet-1586	265	17	printed	print	VERB
admet-1586	265	18	tablets	tablet	NOUN
admet-1586	265	19	:	:	PUNCT
admet-1586	265	20	an	an	DET
admet-1586	265	21	overview	overview	NOUN
admet-1586	265	22	and	and	CCONJ
admet-1586	265	23	commentary	commentary	NOUN
admet-1586	265	24	.	.	PUNCT
admet-1586	266	1	admet	admet	PROPN
admet-1586	266	2	dmpk	dmpk	PROPN
admet-1586	266	3	.	.	PUNCT
admet-1586	267	1	11	11	NUM
admet-1586	267	2	(	(	PUNCT
admet-1586	267	3	2023	2023	NUM
admet-1586	267	4	)	)	PUNCT
admet-1586	267	5	33	33	NUM
admet-1586	267	6	-	-	SYM
admet-1586	267	7	55	55	NUM
admet-1586	267	8	.	.	PUNCT
admet-1586	268	1	https://doi.org/10.5599/admet.1622	https://doi.org/10.5599/admet.1622	VERB
admet-1586	268	2	[	[	X
admet-1586	268	3	11	11	NUM
admet-1586	268	4	]	]	PUNCT
admet-1586	268	5	k.	k.	PROPN
admet-1586	268	6	deboyace	deboyace	PROPN
admet-1586	268	7	,	,	PUNCT
admet-1586	268	8	m.	m.	NOUN
admet-1586	268	9	bookwala	bookwala	PROPN
admet-1586	268	10	,	,	PUNCT
admet-1586	268	11	i.s	i.s	PROPN
admet-1586	268	12	.	.	PROPN
admet-1586	268	13	buckner	buckner	PROPN
admet-1586	268	14	,	,	PUNCT
admet-1586	268	15	d.	d.	PROPN
admet-1586	268	16	zhou	zhou	PROPN
admet-1586	268	17	,	,	PUNCT
admet-1586	268	18	p.l.d	p.l.d	NOUN
admet-1586	268	19	.	.	PUNCT
admet-1586	268	20	wildfong	wildfong	PROPN
admet-1586	268	21	.	.	PUNCT
admet-1586	269	1	interpreting	interpret	VERB
admet-1586	269	2	the	the	DET
admet-1586	269	3	physicochemical	physicochemical	ADJ
admet-1586	269	4	meaning	meaning	NOUN
admet-1586	269	5	of	of	ADP
admet-1586	269	6	a	a	DET
admet-1586	269	7	molecular	molecular	ADJ
admet-1586	269	8	descriptor	descriptor	NOUN
admet-1586	269	9	which	which	PRON
admet-1586	269	10	is	be	AUX
admet-1586	269	11	predictive	predictive	ADJ
admet-1586	269	12	of	of	ADP
admet-1586	269	13	amorphous	amorphous	ADJ
admet-1586	269	14	solid	solid	ADJ
admet-1586	269	15	dispersion	dispersion	NOUN
admet-1586	269	16	formation	formation	NOUN
admet-1586	269	17	in	in	ADP
admet-1586	269	18	polyvinylpyrrolidone	polyvinylpyrrolidone	NOUN
admet-1586	269	19	vinyl	vinyl	NOUN
admet-1586	269	20	acetate	acetate	NOUN
admet-1586	269	21	.	.	PUNCT
admet-1586	270	1	molecular	molecular	ADJ
admet-1586	270	2	pharmaceutics	pharmaceutic	NOUN
admet-1586	270	3	19	19	NUM
admet-1586	270	4	(	(	PUNCT
admet-1586	270	5	2022	2022	NUM
admet-1586	270	6	)	)	PUNCT
admet-1586	270	7	303	303	NUM
admet-1586	270	8	-	-	SYM
admet-1586	270	9	317	317	NUM
admet-1586	270	10	.	.	PUNCT
admet-1586	271	1	https://doi.org/10.1021/acs.molpharmaceut.1c00783	https://doi.org/10.1021/acs.molpharmaceut.1c00783	NOUN
admet-1586	271	2	.	.	PUNCT
admet-1586	272	1	[	[	X
admet-1586	272	2	12	12	NUM
admet-1586	272	3	]	]	X
admet-1586	272	4	b.	b.	PROPN
admet-1586	272	5	tian	tian	PROPN
admet-1586	272	6	,	,	PUNCT
admet-1586	272	7	x.	x.	NOUN
admet-1586	272	8	tang	tang	PROPN
admet-1586	272	9	,	,	PUNCT
admet-1586	272	10	l.s	l.s	PROPN
admet-1586	272	11	.	.	PROPN
admet-1586	272	12	taylor	taylor	PROPN
admet-1586	272	13	.	.	PUNCT
admet-1586	273	1	investigating	investigate	VERB
admet-1586	273	2	the	the	DET
admet-1586	273	3	correlation	correlation	NOUN
admet-1586	273	4	between	between	ADP
admet-1586	273	5	miscibility	miscibility	NOUN
admet-1586	273	6	and	and	CCONJ
admet-1586	273	7	physical	physical	ADJ
admet-1586	273	8	stability	stability	NOUN
admet-1586	273	9	of	of	ADP
admet-1586	273	10	amorphous	amorphous	ADJ
admet-1586	273	11	solid	solid	ADJ
admet-1586	273	12	dispersions	dispersion	NOUN
admet-1586	273	13	using	use	VERB
admet-1586	273	14	fluorescence	fluorescence	NOUN
admet-1586	273	15	-	-	PUNCT
admet-1586	273	16	based	base	VERB
admet-1586	273	17	techniques	technique	NOUN
admet-1586	273	18	.	.	PUNCT
admet-1586	274	1	molecular	molecular	ADJ
admet-1586	274	2	pharmaceutics	pharmaceutic	NOUN
admet-1586	274	3	13	13	NUM
admet-1586	274	4	(	(	PUNCT
admet-1586	274	5	2016	2016	NUM
admet-1586	274	6	)	)	PUNCT
admet-1586	274	7	3988	3988	NUM
admet-1586	274	8	-	-	SYM
admet-1586	274	9	4000	4000	NUM
admet-1586	274	10	.	.	PUNCT
admet-1586	275	1	https://doi.org/10.1021/acs.molpharmaceut.6b00803	https://doi.org/10.1021/acs.molpharmaceut.6b00803	NOUN
admet-1586	275	2	.	.	PUNCT
admet-1586	276	1	[	[	X
admet-1586	276	2	13	13	NUM
admet-1586	276	3	]	]	PUNCT
admet-1586	276	4	f.	f.	PROPN
admet-1586	276	5	qian	qian	PROPN
admet-1586	276	6	,	,	PUNCT
admet-1586	276	7	j.	j.	PROPN
admet-1586	276	8	wang	wang	PROPN
admet-1586	276	9	,	,	PUNCT
admet-1586	276	10	r.	r.	PROPN
admet-1586	276	11	hartley	hartley	PROPN
admet-1586	276	12	,	,	PUNCT
admet-1586	276	13	j.	j.	PROPN
admet-1586	276	14	tao	tao	PROPN
admet-1586	276	15	,	,	PUNCT
admet-1586	276	16	r.	r.	PROPN
admet-1586	276	17	haddadin	haddadin	PROPN
admet-1586	276	18	,	,	PUNCT
admet-1586	276	19	n.	n.	PROPN
admet-1586	276	20	mathias	mathias	PROPN
admet-1586	276	21	,	,	PUNCT
admet-1586	276	22	m.	m.	NOUN
admet-1586	276	23	hussain	hussain	PROPN
admet-1586	276	24	.	.	PUNCT
admet-1586	277	1	solution	solution	NOUN
admet-1586	277	2	behavior	behavior	NOUN
admet-1586	277	3	of	of	ADP
admet-1586	277	4	pvp	pvp	PROPN
admet-1586	277	5	-	-	PUNCT
admet-1586	277	6	va	va	PROPN
admet-1586	277	7	and	and	CCONJ
admet-1586	277	8	hpmc	hpmc	ADJ
admet-1586	277	9	-	-	PUNCT
admet-1586	277	10	as	as	ADV
admet-1586	277	11	-	-	PUNCT
admet-1586	277	12	based	base	VERB
admet-1586	277	13	amorphous	amorphous	ADJ
admet-1586	277	14	solid	solid	ADJ
admet-1586	277	15	dispersions	dispersion	NOUN
admet-1586	277	16	and	and	CCONJ
admet-1586	277	17	their	their	PRON
admet-1586	277	18	bioavailability	bioavailability	NOUN
admet-1586	277	19	implications	implication	NOUN
admet-1586	277	20	.	.	PUNCT
admet-1586	278	1	pharmaceutical	pharmaceutical	ADJ
admet-1586	278	2	research	research	NOUN
admet-1586	278	3	29	29	NUM
admet-1586	278	4	(	(	PUNCT
admet-1586	278	5	2012	2012	NUM
admet-1586	278	6	)	)	PUNCT
admet-1586	278	7	2765	2765	NUM
admet-1586	278	8	-	-	SYM
admet-1586	278	9	2776	2776	NUM
admet-1586	278	10	.	.	PUNCT
admet-1586	279	1	https://doi.org/10.1007/s11095-012-0695-7	https://doi.org/10.1007/s11095-012-0695-7	NUM
admet-1586	279	2	.	.	PUNCT
admet-1586	280	1	[	[	X
admet-1586	280	2	14	14	NUM
admet-1586	280	3	]	]	X
admet-1586	280	4	a.	a.	NOUN
admet-1586	280	5	mitra	mitra	PROPN
admet-1586	280	6	,	,	PUNCT
admet-1586	280	7	l.	l.	PROPN
admet-1586	280	8	li	li	PROPN
admet-1586	280	9	,	,	PUNCT
admet-1586	280	10	p.	p.	NOUN
admet-1586	280	11	marsac	marsac	NOUN
admet-1586	280	12	,	,	PUNCT
admet-1586	280	13	b.	b.	PROPN
admet-1586	280	14	marks	marks	PROPN
admet-1586	280	15	,	,	PUNCT
admet-1586	280	16	z.	z.	PROPN
admet-1586	280	17	liu	liu	PROPN
admet-1586	280	18	,	,	PUNCT
admet-1586	280	19	c.	c.	PROPN
admet-1586	280	20	brown	brown	PROPN
admet-1586	280	21	.	.	PUNCT
admet-1586	281	1	impact	impact	NOUN
admet-1586	281	2	of	of	ADP
admet-1586	281	3	polymer	polymer	NOUN
admet-1586	281	4	type	type	NOUN
admet-1586	281	5	on	on	ADP
admet-1586	281	6	bioperformance	bioperformance	NOUN
admet-1586	281	7	and	and	CCONJ
admet-1586	281	8	physical	physical	ADJ
admet-1586	281	9	stability	stability	NOUN
admet-1586	281	10	of	of	ADP
admet-1586	281	11	hot	hot	ADJ
admet-1586	281	12	melt	melt	NOUN
admet-1586	281	13	extruded	extrude	VERB
admet-1586	281	14	formulations	formulation	NOUN
admet-1586	281	15	of	of	ADP
admet-1586	281	16	a	a	DET
admet-1586	281	17	poorly	poorly	ADV
admet-1586	281	18	water	water	NOUN
admet-1586	281	19	soluble	soluble	ADJ
admet-1586	281	20	drug	drug	NOUN
admet-1586	281	21	.	.	PUNCT
admet-1586	282	1	international	international	ADJ
admet-1586	282	2	journal	journal	PROPN
admet-1586	282	3	of	of	ADP
admet-1586	282	4	pharmaceutics	pharmaceutic	NOUN
admet-1586	282	5	505	505	NUM
admet-1586	282	6	(	(	PUNCT
admet-1586	282	7	2016	2016	NUM
admet-1586	282	8	)	)	PUNCT
admet-1586	282	9	107	107	NUM
admet-1586	282	10	-	-	SYM
admet-1586	282	11	114	114	NUM
admet-1586	282	12	.	.	PUNCT
admet-1586	283	1	https://doi.org/10.1016/j.ijpharm.2016.03.036	https://doi.org/10.1016/j.ijpharm.2016.03.036	X
admet-1586	283	2	.	.	PUNCT
admet-1586	284	1	[	[	X
admet-1586	284	2	15	15	NUM
admet-1586	284	3	]	]	X
admet-1586	284	4	h.	h.	NOUN
admet-1586	284	5	konno	konno	PROPN
admet-1586	284	6	,	,	PUNCT
admet-1586	284	7	l.s	l.s	PROPN
admet-1586	284	8	.	.	PROPN
admet-1586	284	9	taylor	taylor	PROPN
admet-1586	284	10	.	.	PUNCT
admet-1586	285	1	influence	influence	NOUN
admet-1586	285	2	of	of	ADP
admet-1586	285	3	different	different	ADJ
admet-1586	285	4	polymers	polymer	NOUN
admet-1586	285	5	on	on	ADP
admet-1586	285	6	the	the	DET
admet-1586	285	7	crystallization	crystallization	NOUN
admet-1586	285	8	tendency	tendency	NOUN
admet-1586	285	9	of	of	ADP
admet-1586	285	10	molecularly	molecularly	ADV
admet-1586	285	11	dispersed	disperse	VERB
admet-1586	285	12	amorphous	amorphous	ADJ
admet-1586	285	13	felodipine	felodipine	NOUN
admet-1586	285	14	.	.	PUNCT
admet-1586	286	1	journal	journal	NOUN
admet-1586	286	2	of	of	ADP
admet-1586	286	3	pharmaceutical	pharmaceutical	PROPN
admet-1586	286	4	sciences	science	NOUN
admet-1586	286	5	95	95	NUM
admet-1586	286	6	(	(	PUNCT
admet-1586	286	7	2006	2006	NUM
admet-1586	286	8	)	)	PUNCT
admet-1586	286	9	2692	2692	NUM
admet-1586	286	10	-	-	SYM
admet-1586	286	11	2705	2705	NUM
admet-1586	286	12	.	.	PUNCT
admet-1586	287	1	https://doi.org/10.1002/jps.20697	https://doi.org/10.1002/jps.20697	PROPN
admet-1586	287	2	.	.	PUNCT
admet-1586	288	1	[	[	X
admet-1586	288	2	16	16	NUM
admet-1586	288	3	]	]	X
admet-1586	288	4	d.	d.	PROPN
admet-1586	288	5	huang	huang	PROPN
admet-1586	288	6	,	,	PUNCT
admet-1586	288	7	z.	z.	PROPN
admet-1586	288	8	xie	xie	PROPN
admet-1586	288	9	,	,	PUNCT
admet-1586	288	10	q.	q.	PROPN
admet-1586	288	11	rao	rao	PROPN
admet-1586	288	12	,	,	PUNCT
admet-1586	288	13	e.	e.	PROPN
admet-1586	288	14	liamas	liamas	PROPN
admet-1586	288	15	,	,	PUNCT
admet-1586	288	16	p.	p.	PROPN
admet-1586	288	17	pan	pan	PROPN
admet-1586	288	18	,	,	PUNCT
admet-1586	288	19	s.	s.	PROPN
admet-1586	288	20	guan	guan	PROPN
admet-1586	288	21	,	,	PUNCT
admet-1586	288	22	z.j	z.j	PROPN
admet-1586	288	23	.	.	PROPN
admet-1586	288	24	zhang	zhang	PROPN
admet-1586	288	25	,	,	PUNCT
admet-1586	288	26	m.	m.	PROPN
admet-1586	288	27	lu	lu	PROPN
admet-1586	288	28	,	,	PUNCT
admet-1586	288	29	q.	q.	PROPN
admet-1586	288	30	li	li	PROPN
admet-1586	288	31	.	.	PUNCT
admet-1586	288	32	hot	hot	ADJ
admet-1586	288	33	melt	melt	NOUN
admet-1586	288	34	extrusion	extrusion	NOUN
admet-1586	288	35	of	of	ADP
admet-1586	288	36	heat	heat	NOUN
admet-1586	288	37	-	-	PUNCT
admet-1586	288	38	sensitive	sensitive	ADJ
admet-1586	288	39	and	and	CCONJ
admet-1586	288	40	high	high	ADJ
admet-1586	288	41	melting	melting	NOUN
admet-1586	288	42	point	point	NOUN
admet-1586	288	43	drug	drug	NOUN
admet-1586	288	44	:	:	PUNCT
admet-1586	288	45	inhibit	inhibit	VERB
admet-1586	288	46	the	the	DET
admet-1586	288	47	recrystallization	recrystallization	NOUN
admet-1586	288	48	of	of	ADP
admet-1586	288	49	the	the	DET
admet-1586	288	50	prepared	prepared	ADJ
admet-1586	288	51	amorphous	amorphous	ADJ
admet-1586	288	52	drug	drug	NOUN
admet-1586	288	53	during	during	ADP
admet-1586	288	54	extrusion	extrusion	NOUN
admet-1586	288	55	to	to	PART
admet-1586	288	56	improve	improve	VERB
admet-1586	288	57	the	the	DET
admet-1586	288	58	bioavailability	bioavailability	NOUN
admet-1586	288	59	.	.	PUNCT
admet-1586	289	1	international	international	ADJ
admet-1586	289	2	journal	journal	PROPN
admet-1586	289	3	of	of	ADP
admet-1586	289	4	pharmaceutics	pharmaceutic	NOUN
admet-1586	289	5	565	565	NUM
admet-1586	289	6	(	(	PUNCT
admet-1586	289	7	2019	2019	NUM
admet-1586	289	8	)	)	PUNCT
admet-1586	289	9	316	316	NUM
admet-1586	289	10	-	-	SYM
admet-1586	289	11	324	324	NUM
admet-1586	289	12	.	.	PUNCT
admet-1586	290	1	https://doi.org/10.1016/j.ijpharm.2019.04.064	https://doi.org/10.1016/j.ijpharm.2019.04.064	NOUN
admet-1586	290	2	.	.	PUNCT
admet-1586	291	1	[	[	X
admet-1586	291	2	17	17	NUM
admet-1586	291	3	]	]	PUNCT
admet-1586	291	4	a.	a.	NOUN
admet-1586	291	5	kapourani	kapourani	PROPN
admet-1586	291	6	,	,	PUNCT
admet-1586	291	7	t.	t.	PROPN
admet-1586	291	8	tzakri	tzakri	PROPN
admet-1586	291	9	,	,	PUNCT
admet-1586	291	10	v.	v.	ADP
admet-1586	291	11	valkanioti	valkanioti	PROPN
admet-1586	291	12	,	,	PUNCT
admet-1586	291	13	k.n	k.n	PROPN
admet-1586	291	14	.	.	PROPN
admet-1586	291	15	kontogiannopoulos	kontogiannopoulos	PROPN
admet-1586	291	16	,	,	PUNCT
admet-1586	291	17	p.	p.	PROPN
admet-1586	291	18	barmpalexis	barmpalexis	PROPN
admet-1586	291	19	.	.	PUNCT
admet-1586	292	1	drug	drug	NOUN
admet-1586	292	2	crystal	crystal	NOUN
admet-1586	292	3	growth	growth	NOUN
admet-1586	292	4	in	in	ADP
admet-1586	292	5	ternary	ternary	ADJ
admet-1586	292	6	amorphous	amorphous	ADJ
admet-1586	292	7	solid	solid	ADJ
admet-1586	292	8	dispersions	dispersion	NOUN
admet-1586	292	9	:	:	PUNCT
admet-1586	292	10	effect	effect	NOUN
admet-1586	292	11	of	of	ADP
admet-1586	292	12	surfactants	surfactant	NOUN
admet-1586	292	13	and	and	CCONJ
admet-1586	292	14	polymeric	polymeric	ADJ
admet-1586	292	15	matrix	matrix	NOUN
admet-1586	292	16	-	-	PUNCT
admet-1586	292	17	carriers	carrier	NOUN
admet-1586	292	18	.	.	PUNCT
admet-1586	293	1	international	international	ADJ
admet-1586	293	2	journal	journal	PROPN
admet-1586	293	3	of	of	ADP
admet-1586	293	4	pharmaceutics	pharmaceutic	NOUN
admet-1586	293	5	:	:	PUNCT
admet-1586	293	6	x	x	SYM
admet-1586	293	7	3	3	NUM
admet-1586	293	8	(	(	PUNCT
admet-1586	293	9	2021	2021	NUM
admet-1586	293	10	)	)	PUNCT
admet-1586	293	11	100086	100086	NUM
admet-1586	293	12	.	.	PUNCT
admet-1586	294	1	https://doi.org/10.1016/j.ijpx.2021.100086	https://doi.org/10.1016/j.ijpx.2021.100086	PROPN
admet-1586	294	2	.	.	PUNCT
admet-1586	295	1	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	PROPN
admet-1586	295	2	https://doi.org/10.1080/17425247.2020.1796631	https://doi.org/10.1080/17425247.2020.1796631	PROPN
admet-1586	295	3	https://doi.org/10.1124/pr.112.005660	https://doi.org/10.1124/pr.112.005660	NOUN
admet-1586	295	4	https://doi.org/10.1016/j.ijpharm.2020.119560	https://doi.org/10.1016/j.ijpharm.2020.119560	PROPN
admet-1586	295	5	https://doi.org/10.1080/10717544.2020.1846638	https://doi.org/10.1080/10717544.2020.1846638	PROPN
admet-1586	295	6	https://doi.org/10.1016/j.ijpharm.2021.121387	https://doi.org/10.1016/j.ijpharm.2021.121387	PROPN
admet-1586	295	7	https://doi.org/10.1016/j.drudis.2019.05.013	https://doi.org/10.1016/j.drudis.2019.05.013	PROPN
admet-1586	295	8	https://doi.org/10.1016/j.jddst.2019.101459	https://doi.org/10.1016/j.jddst.2019.101459	PROPN
admet-1586	295	9	https://doi.org/10.5599/admet.1622	https://doi.org/10.5599/admet.1622	VERB
admet-1586	295	10	https://doi.org/10.1021/acs.molpharmaceut.1c00783	https://doi.org/10.1021/acs.molpharmaceut.1c00783	NOUN
admet-1586	295	11	https://doi.org/10.1021/acs.molpharmaceut.6b00803	https://doi.org/10.1021/acs.molpharmaceut.6b00803	NOUN
admet-1586	295	12	https://doi.org/10.1007/s11095-012-0695-7	https://doi.org/10.1007/s11095-012-0695-7	NOUN
admet-1586	295	13	https://doi.org/10.1016/j.ijpharm.2016.03.036	https://doi.org/10.1016/j.ijpharm.2016.03.036	NOUN
admet-1586	296	1	https://doi.org/10.1002/jps.20697	https://doi.org/10.1002/jps.20697	VERB
admet-1586	296	2	https://doi.org/10.1016/j.ijpharm.2019.04.064	https://doi.org/10.1016/j.ijpharm.2019.04.064	PROPN
admet-1586	297	1	https://doi.org/10.1016/j.ijpx.2021.100086	https://doi.org/10.1016/j.ijpx.2021.100086	PROPN
admet-1586	297	2	h.	h.	PROPN
admet-1586	297	3	tanaka	tanaka	PROPN
admet-1586	297	4	et	et	PROPN
admet-1586	297	5	al	al	PROPN
admet-1586	297	6	.	.	PROPN
admet-1586	297	7	admet	admet	PROPN
admet-1586	297	8	&	&	CCONJ
admet-1586	297	9	dmpk	dmpk	PROPN
admet-1586	297	10	11(3	11(3	NUM
admet-1586	297	11	)	)	PUNCT
admet-1586	297	12	(	(	PUNCT
admet-1586	297	13	2023	2023	NUM
admet-1586	297	14	)	)	PUNCT
admet-1586	297	15	373	373	NUM
admet-1586	297	16	-	-	SYM
admet-1586	297	17	385	385	NUM
admet-1586	297	18	384	384	NUM
admet-1586	297	19	[	[	X
admet-1586	297	20	18	18	NUM
admet-1586	297	21	]	]	X
admet-1586	297	22	n.	n.	NOUN
admet-1586	297	23	siriwannakij	siriwannakij	NOUN
admet-1586	297	24	,	,	PUNCT
admet-1586	297	25	t.	t.	NOUN
admet-1586	297	26	heimbach	heimbach	NOUN
admet-1586	297	27	,	,	PUNCT
admet-1586	297	28	a.t.m	a.t.m	PROPN
admet-1586	297	29	.	.	PUNCT
admet-1586	298	1	serajuddin	serajuddin	VERB
admet-1586	298	2	.	.	PUNCT
admet-1586	299	1	aqueous	aqueous	ADJ
admet-1586	299	2	dissolution	dissolution	NOUN
admet-1586	299	3	and	and	CCONJ
admet-1586	299	4	dispersion	dispersion	NOUN
admet-1586	299	5	behavior	behavior	NOUN
admet-1586	299	6	of	of	ADP
admet-1586	299	7	polyvinylpyrrolidone	polyvinylpyrrolidone	NOUN
admet-1586	299	8	vinyl	vinyl	NOUN
admet-1586	299	9	acetate	acetate	NOUN
admet-1586	299	10	-	-	PUNCT
admet-1586	299	11	based	base	VERB
admet-1586	299	12	amorphous	amorphous	ADJ
admet-1586	299	13	solid	solid	ADJ
admet-1586	299	14	dispersion	dispersion	NOUN
admet-1586	299	15	of	of	ADP
admet-1586	299	16	ritonavir	ritonavir	PRON
admet-1586	299	17	prepared	prepare	VERB
admet-1586	299	18	by	by	ADP
admet-1586	299	19	hotmelt	hotmelt	NOUN
admet-1586	299	20	extrusion	extrusion	NOUN
admet-1586	299	21	with	with	ADP
admet-1586	299	22	and	and	CCONJ
admet-1586	299	23	without	without	ADP
admet-1586	299	24	added	add	VERB
admet-1586	299	25	surfactants	surfactant	NOUN
admet-1586	299	26	.	.	PUNCT
admet-1586	300	1	journal	journal	NOUN
admet-1586	300	2	of	of	ADP
admet-1586	300	3	pharmaceutical	pharmaceutical	PROPN
admet-1586	300	4	sciences	science	NOUN
admet-1586	300	5	110	110	NUM
admet-1586	300	6	(	(	PUNCT
admet-1586	300	7	2021	2021	NUM
admet-1586	300	8	)	)	PUNCT
admet-1586	300	9	1480	1480	NUM
admet-1586	300	10	-	-	SYM
admet-1586	300	11	1494	1494	NUM
admet-1586	300	12	.	.	PUNCT
admet-1586	301	1	https://doi.org/10.1016/j.xphs.2020.08.007	https://doi.org/10.1016/j.xphs.2020.08.007	VERB
admet-1586	301	2	.	.	PUNCT
admet-1586	302	1	[	[	X
admet-1586	302	2	19	19	NUM
admet-1586	302	3	]	]	X
admet-1586	302	4	h.	h.	PROPN
admet-1586	302	5	ueda	ueda	PROPN
admet-1586	302	6	,	,	PUNCT
admet-1586	302	7	y.	y.	PROPN
admet-1586	302	8	hirakawa	hirakawa	PROPN
admet-1586	302	9	,	,	PUNCT
admet-1586	302	10	h.	h.	PROPN
admet-1586	302	11	tanaka	tanaka	PROPN
admet-1586	302	12	,	,	PUNCT
admet-1586	302	13	t.	t.	PROPN
admet-1586	302	14	miyano	miyano	PROPN
admet-1586	302	15	,	,	PUNCT
admet-1586	302	16	k.	k.	PROPN
admet-1586	302	17	sugita	sugita	PROPN
admet-1586	302	18	.	.	PUNCT
admet-1586	303	1	applicability	applicability	NOUN
admet-1586	303	2	of	of	ADP
admet-1586	303	3	an	an	DET
admet-1586	303	4	experimental	experimental	ADJ
admet-1586	303	5	grade	grade	NOUN
admet-1586	303	6	of	of	ADP
admet-1586	303	7	hydroxypropyl	hydroxypropyl	ADJ
admet-1586	303	8	methylcellulose	methylcellulose	NOUN
admet-1586	303	9	acetate	acetate	NOUN
admet-1586	303	10	succinate	succinate	NOUN
admet-1586	303	11	as	as	ADP
admet-1586	303	12	a	a	DET
admet-1586	303	13	carrier	carrier	NOUN
admet-1586	303	14	for	for	ADP
admet-1586	303	15	formation	formation	NOUN
admet-1586	303	16	of	of	ADP
admet-1586	303	17	solid	solid	ADJ
admet-1586	303	18	dispersion	dispersion	NOUN
admet-1586	303	19	with	with	ADP
admet-1586	303	20	indomethacin	indomethacin	PROPN
admet-1586	303	21	.	.	PUNCT
admet-1586	304	1	pharmaceutics	pharmaceutic	NOUN
admet-1586	304	2	13	13	NUM
admet-1586	304	3	(	(	PUNCT
admet-1586	304	4	2021	2021	NUM
admet-1586	304	5	)	)	PUNCT
admet-1586	304	6	353	353	NUM
admet-1586	304	7	.	.	PUNCT
admet-1586	305	1	https://doi.org/10.3390/pharmaceutics13030353	https://doi.org/10.3390/pharmaceutics13030353	PROPN
admet-1586	305	2	.	.	PUNCT
admet-1586	306	1	[	[	X
admet-1586	306	2	20	20	NUM
admet-1586	306	3	]	]	PUNCT
admet-1586	306	4	m.	m.	NOUN
admet-1586	306	5	imono	imono	PROPN
admet-1586	306	6	,	,	PUNCT
admet-1586	306	7	h.	h.	PROPN
admet-1586	306	8	uchiyama	uchiyama	PROPN
admet-1586	306	9	,	,	PUNCT
admet-1586	306	10	h.	h.	PROPN
admet-1586	306	11	ueda	ueda	PROPN
admet-1586	306	12	,	,	PUNCT
admet-1586	306	13	k.	k.	PROPN
admet-1586	306	14	kadota	kadota	PROPN
admet-1586	306	15	,	,	PUNCT
admet-1586	306	16	y.	y.	PROPN
admet-1586	306	17	tozuka	tozuka	PROPN
admet-1586	306	18	.	.	PUNCT
admet-1586	307	1	in	in	ADP
admet-1586	307	2	-	-	PUNCT
admet-1586	307	3	situ	situ	NOUN
admet-1586	307	4	dissolution	dissolution	NOUN
admet-1586	307	5	and	and	CCONJ
admet-1586	307	6	permeation	permeation	NOUN
admet-1586	307	7	studies	study	NOUN
admet-1586	307	8	of	of	ADP
admet-1586	307	9	nanocrystal	nanocrystal	ADJ
admet-1586	307	10	formulations	formulation	NOUN
admet-1586	307	11	with	with	ADP
admet-1586	307	12	second	second	ADJ
admet-1586	307	13	-	-	PUNCT
admet-1586	307	14	derivative	derivative	ADJ
admet-1586	307	15	uv	uv	NOUN
admet-1586	307	16	spectroscopy	spectroscopy	NOUN
admet-1586	307	17	.	.	PUNCT
admet-1586	308	1	international	international	ADJ
admet-1586	308	2	journal	journal	PROPN
admet-1586	308	3	of	of	ADP
admet-1586	308	4	pharmaceutics	pharmaceutic	NOUN
admet-1586	308	5	558	558	NUM
admet-1586	308	6	(	(	PUNCT
admet-1586	308	7	2019	2019	NUM
admet-1586	308	8	)	)	PUNCT
admet-1586	308	9	242	242	NUM
admet-1586	308	10	-	-	SYM
admet-1586	308	11	249	249	NUM
admet-1586	308	12	.	.	PUNCT
admet-1586	309	1	https://doi.org/10.1016/j.ijpharm.2018.12.086	https://doi.org/10.1016/j.ijpharm.2018.12.086	VERB
admet-1586	309	2	.	.	PUNCT
admet-1586	310	1	[	[	X
admet-1586	310	2	21	21	NUM
admet-1586	310	3	]	]	X
admet-1586	310	4	e.	e.	PROPN
admet-1586	310	5	borbás	borbás	PROPN
admet-1586	310	6	,	,	PUNCT
admet-1586	310	7	z.k	z.k	PROPN
admet-1586	310	8	.	.	PROPN
admet-1586	310	9	nagy	nagy	PROPN
admet-1586	310	10	,	,	PUNCT
admet-1586	310	11	b.	b.	PROPN
admet-1586	310	12	nagy	nagy	PROPN
admet-1586	310	13	,	,	PUNCT
admet-1586	310	14	a.	a.	PROPN
admet-1586	310	15	balogh	balogh	PROPN
admet-1586	310	16	,	,	PUNCT
admet-1586	310	17	b.	b.	PROPN
admet-1586	310	18	farkas	farkas	PROPN
admet-1586	310	19	,	,	PUNCT
admet-1586	310	20	o.	o.	PROPN
admet-1586	310	21	tsinman	tsinman	PROPN
admet-1586	310	22	,	,	PUNCT
admet-1586	310	23	k.	k.	PROPN
admet-1586	310	24	tsinman	tsinman	PROPN
admet-1586	310	25	,	,	PUNCT
admet-1586	310	26	b.	b.	PROPN
admet-1586	310	27	sinkó	sinkó	PROPN
admet-1586	310	28	.	.	PUNCT
admet-1586	311	1	the	the	DET
admet-1586	311	2	effect	effect	NOUN
admet-1586	311	3	of	of	ADP
admet-1586	311	4	formulation	formulation	NOUN
admet-1586	311	5	additives	additive	NOUN
admet-1586	311	6	on	on	ADP
admet-1586	311	7	in	in	ADP
admet-1586	311	8	vitro	vitro	X
admet-1586	311	9	dissolution	dissolution	NOUN
admet-1586	311	10	-	-	PUNCT
admet-1586	311	11	absorption	absorption	NOUN
admet-1586	311	12	profile	profile	NOUN
admet-1586	311	13	and	and	CCONJ
admet-1586	311	14	in	in	ADP
admet-1586	311	15	vivo	vivo	ADJ
admet-1586	311	16	bioavailability	bioavailability	NOUN
admet-1586	311	17	of	of	ADP
admet-1586	311	18	telmisartan	telmisartan	NOUN
admet-1586	311	19	from	from	ADP
admet-1586	311	20	brand	brand	NOUN
admet-1586	311	21	and	and	CCONJ
admet-1586	311	22	generic	generic	ADJ
admet-1586	311	23	formulations	formulation	NOUN
admet-1586	311	24	.	.	PUNCT
admet-1586	312	1	european	european	ADJ
admet-1586	312	2	journal	journal	PROPN
admet-1586	312	3	of	of	ADP
admet-1586	312	4	pharmaceutical	pharmaceutical	PROPN
admet-1586	312	5	sciences	science	NOUN
admet-1586	312	6	114	114	NUM
admet-1586	312	7	(	(	PUNCT
admet-1586	312	8	2018	2018	NUM
admet-1586	312	9	)	)	PUNCT
admet-1586	312	10	310	310	NUM
admet-1586	312	11	-	-	SYM
admet-1586	312	12	317	317	NUM
admet-1586	312	13	.	.	PUNCT
admet-1586	313	1	https://doi.org/10.1016/j.ejps.2017.12.029	https://doi.org/10.1016/j.ejps.2017.12.029	NOUN
admet-1586	313	2	.	.	PUNCT
admet-1586	314	1	[	[	X
admet-1586	314	2	22	22	NUM
admet-1586	314	3	]	]	PUNCT
admet-1586	314	4	j.	j.	PROPN
admet-1586	314	5	li	li	PROPN
admet-1586	314	6	,	,	PUNCT
admet-1586	314	7	k.	k.	PROPN
admet-1586	314	8	tsinman	tsinman	PROPN
admet-1586	314	9	,	,	PUNCT
admet-1586	314	10	o.	o.	PROPN
admet-1586	314	11	tsinman	tsinman	PROPN
admet-1586	314	12	,	,	PUNCT
admet-1586	314	13	l.	l.	PROPN
admet-1586	314	14	wigman	wigman	PROPN
admet-1586	314	15	.	.	PUNCT
admet-1586	315	1	using	use	VERB
admet-1586	315	2	ph	ph	PROPN
admet-1586	315	3	gradient	gradient	NOUN
admet-1586	315	4	dissolution	dissolution	NOUN
admet-1586	315	5	with	with	ADP
admet-1586	315	6	in	in	ADP
admet-1586	315	7	-	-	PUNCT
admet-1586	315	8	situ	situ	ADJ
admet-1586	315	9	flux	flux	NOUN
admet-1586	315	10	measurement	measurement	NOUN
admet-1586	315	11	to	to	PART
admet-1586	315	12	evaluate	evaluate	VERB
admet-1586	315	13	bioavailability	bioavailability	NOUN
admet-1586	315	14	and	and	CCONJ
admet-1586	315	15	ddi	ddi	NOUN
admet-1586	315	16	for	for	ADP
admet-1586	315	17	formulated	formulate	VERB
admet-1586	315	18	poorly	poorly	ADV
admet-1586	315	19	soluble	soluble	ADJ
admet-1586	315	20	drug	drug	NOUN
admet-1586	315	21	products	product	NOUN
admet-1586	315	22	.	.	PUNCT
admet-1586	316	1	aaps	aap	NOUN
admet-1586	316	2	pharmscitech	pharmscitech	VERB
admet-1586	316	3	.	.	PUNCT
admet-1586	317	1	19	19	NUM
admet-1586	317	2	(	(	PUNCT
admet-1586	317	3	2018	2018	NUM
admet-1586	317	4	)	)	PUNCT
admet-1586	317	5	2898	2898	NUM
admet-1586	317	6	-	-	SYM
admet-1586	317	7	2907	2907	NUM
admet-1586	317	8	.	.	PUNCT
admet-1586	318	1	https://doi.org/10.1208/s12249-018-1164-3	https://doi.org/10.1208/s12249-018-1164-3	NOUN
admet-1586	318	2	.	.	PUNCT
admet-1586	319	1	[	[	X
admet-1586	319	2	23	23	NUM
admet-1586	319	3	]	]	PUNCT
admet-1586	319	4	m.	m.	NOUN
admet-1586	319	5	imono	imono	PROPN
admet-1586	319	6	,	,	PUNCT
admet-1586	319	7	h.	h.	PROPN
admet-1586	319	8	uchiyama	uchiyama	PROPN
admet-1586	319	9	,	,	PUNCT
admet-1586	319	10	s.	s.	PROPN
admet-1586	319	11	yoshida	yoshida	PROPN
admet-1586	319	12	,	,	PUNCT
admet-1586	319	13	s.	s.	PROPN
admet-1586	319	14	miyazaki	miyazaki	PROPN
admet-1586	319	15	,	,	PUNCT
admet-1586	319	16	n.	n.	PROPN
admet-1586	319	17	tamura	tamura	PROPN
admet-1586	319	18	,	,	PUNCT
admet-1586	319	19	h.	h.	PROPN
admet-1586	319	20	tsutsumimoto	tsutsumimoto	PROPN
admet-1586	319	21	,	,	PUNCT
admet-1586	319	22	k.	k.	PROPN
admet-1586	319	23	kadota	kadota	PROPN
admet-1586	319	24	,	,	PUNCT
admet-1586	319	25	y.	y.	PROPN
admet-1586	319	26	tozuka	tozuka	PROPN
admet-1586	319	27	.	.	PUNCT
admet-1586	320	1	the	the	DET
admet-1586	320	2	elucidation	elucidation	NOUN
admet-1586	320	3	of	of	ADP
admet-1586	320	4	key	key	ADJ
admet-1586	320	5	factors	factor	NOUN
admet-1586	320	6	for	for	ADP
admet-1586	320	7	oral	oral	ADJ
admet-1586	320	8	absorption	absorption	NOUN
admet-1586	320	9	enhancement	enhancement	NOUN
admet-1586	320	10	of	of	ADP
admet-1586	320	11	nanocrystal	nanocrystal	ADJ
admet-1586	320	12	formulations	formulation	NOUN
admet-1586	320	13	:	:	PUNCT
admet-1586	320	14	in	in	ADP
admet-1586	320	15	vitroin	vitroin	ADJ
admet-1586	320	16	vivo	vivo	NOUN
admet-1586	320	17	correlation	correlation	NOUN
admet-1586	320	18	of	of	ADP
admet-1586	320	19	nanocrystals	nanocrystal	NOUN
admet-1586	320	20	.	.	PUNCT
admet-1586	321	1	european	european	ADJ
admet-1586	321	2	journal	journal	PROPN
admet-1586	321	3	of	of	ADP
admet-1586	321	4	pharmaceutics	pharmaceutic	NOUN
admet-1586	321	5	and	and	CCONJ
admet-1586	321	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1586	321	7	146	146	NUM
admet-1586	321	8	(	(	PUNCT
admet-1586	321	9	2020	2020	NUM
admet-1586	321	10	)	)	PUNCT
admet-1586	321	11	84	84	NUM
admet-1586	321	12	-	-	SYM
admet-1586	321	13	92	92	NUM
admet-1586	321	14	.	.	PUNCT
admet-1586	322	1	https://doi.org/10.1016/j.ejpb.2019.12.002	https://doi.org/10.1016/j.ejpb.2019.12.002	NOUN
admet-1586	322	2	.	.	PUNCT
admet-1586	323	1	[	[	X
admet-1586	323	2	24	24	NUM
admet-1586	323	3	]	]	PUNCT
admet-1586	323	4	a.m.	a.m.	PROPN
admet-1586	323	5	stewart	stewart	PROPN
admet-1586	323	6	,	,	PUNCT
admet-1586	323	7	m.e	m.e	PROPN
admet-1586	323	8	.	.	PROPN
admet-1586	323	9	grass	grass	PROPN
admet-1586	323	10	,	,	PUNCT
admet-1586	323	11	t.j	t.j	PROPN
admet-1586	323	12	.	.	PROPN
admet-1586	323	13	brodeur	brodeur	PROPN
admet-1586	323	14	,	,	PUNCT
admet-1586	323	15	a.k	a.k	PROPN
admet-1586	323	16	.	.	PROPN
admet-1586	323	17	goodwin	goodwin	PROPN
admet-1586	323	18	,	,	PUNCT
admet-1586	323	19	m.m	m.m	PROPN
admet-1586	323	20	.	.	PROPN
admet-1586	323	21	morgen	morgen	PROPN
admet-1586	323	22	,	,	PUNCT
admet-1586	323	23	d.t	d.t	PROPN
admet-1586	323	24	.	.	PROPN
admet-1586	323	25	friesen	friesen	PROPN
admet-1586	323	26	,	,	PUNCT
admet-1586	323	27	d.t	d.t	PROPN
admet-1586	323	28	.	.	PROPN
admet-1586	323	29	vodak	vodak	PROPN
admet-1586	323	30	.	.	PUNCT
admet-1586	324	1	impact	impact	NOUN
admet-1586	324	2	of	of	ADP
admet-1586	324	3	drug	drug	NOUN
admet-1586	324	4	-	-	PUNCT
admet-1586	324	5	rich	rich	ADJ
admet-1586	324	6	colloids	colloid	NOUN
admet-1586	324	7	of	of	ADP
admet-1586	324	8	itraconazole	itraconazole	NOUN
admet-1586	324	9	and	and	CCONJ
admet-1586	324	10	hpmcas	hpmca	NOUN
admet-1586	324	11	on	on	ADP
admet-1586	324	12	membrane	membrane	NOUN
admet-1586	324	13	flux	flux	NOUN
admet-1586	324	14	in	in	ADP
admet-1586	324	15	vitro	vitro	X
admet-1586	324	16	and	and	CCONJ
admet-1586	324	17	oral	oral	ADJ
admet-1586	324	18	bioavailability	bioavailability	NOUN
admet-1586	324	19	in	in	ADP
admet-1586	324	20	rats	rat	NOUN
admet-1586	324	21	.	.	PUNCT
admet-1586	325	1	molecular	molecular	ADJ
admet-1586	325	2	pharmaceutics	pharmaceutic	NOUN
admet-1586	325	3	14	14	NUM
admet-1586	325	4	(	(	PUNCT
admet-1586	325	5	2017	2017	NUM
admet-1586	325	6	)	)	PUNCT
admet-1586	325	7	2437	2437	NUM
admet-1586	325	8	-	-	SYM
admet-1586	325	9	2449	2449	NUM
admet-1586	325	10	.	.	PUNCT
admet-1586	326	1	https://doi.org/10.1021/acs.molpharmaceut.7b00338	https://doi.org/10.1021/acs.molpharmaceut.7b00338	NUM
admet-1586	326	2	.	.	PUNCT
admet-1586	327	1	[	[	X
admet-1586	327	2	25	25	NUM
admet-1586	327	3	]	]	PUNCT
admet-1586	327	4	i.	i.	NOUN
admet-1586	327	5	ozgüney	ozgüney	PROPN
admet-1586	327	6	,	,	PUNCT
admet-1586	327	7	d.	d.	PROPN
admet-1586	327	8	shuwisitkul	shuwisitkul	PROPN
admet-1586	327	9	,	,	PUNCT
admet-1586	327	10	r.	r.	PROPN
admet-1586	327	11	bodmeier	bodmeier	PROPN
admet-1586	327	12	.	.	PUNCT
admet-1586	328	1	development	development	NOUN
admet-1586	328	2	and	and	CCONJ
admet-1586	328	3	characterization	characterization	NOUN
admet-1586	328	4	of	of	ADP
admet-1586	328	5	extended	extend	VERB
admet-1586	328	6	release	release	NOUN
admet-1586	328	7	kollidon	kollidon	PROPN
admet-1586	328	8	sr	sr	PROPN
admet-1586	328	9	mini	mini	NOUN
admet-1586	328	10	-	-	NOUN
admet-1586	328	11	matrices	matrix	NOUN
admet-1586	328	12	prepared	prepare	VERB
admet-1586	328	13	by	by	ADP
admet-1586	328	14	hot	hot	ADJ
admet-1586	328	15	-	-	PUNCT
admet-1586	328	16	melt	melt	NOUN
admet-1586	328	17	extrusion	extrusion	NOUN
admet-1586	328	18	.	.	PUNCT
admet-1586	329	1	european	european	ADJ
admet-1586	329	2	journal	journal	PROPN
admet-1586	329	3	of	of	ADP
admet-1586	329	4	pharmaceutics	pharmaceutic	NOUN
admet-1586	329	5	and	and	CCONJ
admet-1586	329	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1586	329	7	73	73	NUM
admet-1586	329	8	(	(	PUNCT
admet-1586	329	9	2009	2009	NUM
admet-1586	329	10	)	)	PUNCT
admet-1586	329	11	140	140	NUM
admet-1586	329	12	-	-	SYM
admet-1586	329	13	145	145	NUM
admet-1586	329	14	.	.	PUNCT
admet-1586	330	1	https://doi.org/10.1016/j.ejpb.2009.04.006	https://doi.org/10.1016/j.ejpb.2009.04.006	NOUN
admet-1586	330	2	.	.	PUNCT
admet-1586	331	1	[	[	X
admet-1586	331	2	26	26	NUM
admet-1586	331	3	]	]	X
admet-1586	331	4	p.a	p.a	PROPN
admet-1586	331	5	.	.	PROPN
admet-1586	331	6	priemel	priemel	PROPN
admet-1586	331	7	,	,	PUNCT
admet-1586	331	8	r.	r.	PROPN
admet-1586	331	9	laitinen	laitinen	PROPN
admet-1586	331	10	,	,	PUNCT
admet-1586	331	11	h.	h.	PROPN
admet-1586	331	12	grohganz	grohganz	PROPN
admet-1586	331	13	,	,	PUNCT
admet-1586	331	14	t.	t.	PROPN
admet-1586	331	15	rades	rades	PROPN
admet-1586	331	16	,	,	PUNCT
admet-1586	331	17	c.j	c.j	PROPN
admet-1586	331	18	.	.	PROPN
admet-1586	331	19	strachan	strachan	PROPN
admet-1586	331	20	.	.	PUNCT
admet-1586	332	1	in	in	ADP
admet-1586	332	2	situ	situ	ADJ
admet-1586	332	3	amorphisation	amorphisation	NOUN
admet-1586	332	4	of	of	ADP
admet-1586	332	5	indomethacin	indomethacin	NOUN
admet-1586	332	6	with	with	ADP
admet-1586	332	7	eudragit	eudragit	ADJ
admet-1586	332	8	®	®	NOUN
admet-1586	332	9	e	e	NOUN
admet-1586	332	10	during	during	ADP
admet-1586	332	11	dissolution	dissolution	NOUN
admet-1586	332	12	.	.	PUNCT
admet-1586	333	1	european	european	PROPN
admet-1586	333	2	journal	journal	PROPN
admet-1586	333	3	of	of	ADP
admet-1586	333	4	pharmaceutics	pharmaceutic	NOUN
admet-1586	333	5	and	and	CCONJ
admet-1586	333	6	biopharmaceutics	biopharmaceutic	NOUN
admet-1586	333	7	85	85	NUM
admet-1586	333	8	(	(	PUNCT
admet-1586	333	9	2013	2013	NUM
admet-1586	333	10	)	)	PUNCT
admet-1586	333	11	1259	1259	NUM
admet-1586	333	12	-	-	SYM
admet-1586	333	13	1265	1265	NUM
admet-1586	333	14	.	.	PUNCT
admet-1586	334	1	https://doi.org/10.1016/j.ejpb.2013.09.010	https://doi.org/10.1016/j.ejpb.2013.09.010	NOUN
admet-1586	334	2	.	.	PUNCT
admet-1586	335	1	[	[	X
admet-1586	335	2	27	27	NUM
admet-1586	335	3	]	]	X
admet-1586	335	4	h.	h.	PROPN
admet-1586	335	5	wickström	wickström	PROPN
admet-1586	335	6	,	,	PUNCT
admet-1586	335	7	m.	m.	PROPN
admet-1586	335	8	palo	palo	PROPN
admet-1586	335	9	,	,	PUNCT
admet-1586	335	10	k.	k.	PROPN
admet-1586	335	11	rijckaert	rijckaert	PROPN
admet-1586	335	12	,	,	PUNCT
admet-1586	335	13	r.	r.	PROPN
admet-1586	335	14	kolakovic	kolakovic	PROPN
admet-1586	335	15	,	,	PUNCT
admet-1586	335	16	j.o	j.o	PROPN
admet-1586	335	17	.	.	PROPN
admet-1586	335	18	nyman	nyman	PROPN
admet-1586	335	19	,	,	PUNCT
admet-1586	335	20	a.	a.	NOUN
admet-1586	335	21	määttänen	määttänen	PROPN
admet-1586	335	22	,	,	PUNCT
admet-1586	335	23	p.	p.	NOUN
admet-1586	335	24	ihalainen	ihalainen	PROPN
admet-1586	335	25	,	,	PUNCT
admet-1586	335	26	j.	j.	PROPN
admet-1586	335	27	peltonen	peltonen	PROPN
admet-1586	335	28	,	,	PUNCT
admet-1586	335	29	n.	n.	NOUN
admet-1586	335	30	genina	genina	NOUN
admet-1586	335	31	,	,	PUNCT
admet-1586	335	32	t.	t.	PROPN
admet-1586	335	33	de	de	PROPN
admet-1586	335	34	beer	beer	PROPN
admet-1586	335	35	,	,	PUNCT
admet-1586	335	36	k.	k.	PROPN
admet-1586	335	37	löbmann	löbmann	PROPN
admet-1586	335	38	,	,	PUNCT
admet-1586	335	39	t.	t.	PROPN
admet-1586	335	40	rades	rades	PROPN
admet-1586	335	41	,	,	PUNCT
admet-1586	335	42	n.	n.	NOUN
admet-1586	335	43	sandler	sandler	PROPN
admet-1586	335	44	.	.	PUNCT
admet-1586	336	1	improvement	improvement	NOUN
admet-1586	336	2	of	of	ADP
admet-1586	336	3	dissolution	dissolution	ADJ
admet-1586	336	4	rate	rate	NOUN
admet-1586	336	5	of	of	ADP
admet-1586	336	6	indomethacin	indomethacin	NOUN
admet-1586	336	7	by	by	ADP
admet-1586	336	8	inkjet	inkjet	NOUN
admet-1586	336	9	printing	printing	NOUN
admet-1586	336	10	.	.	PUNCT
admet-1586	337	1	european	european	PROPN
admet-1586	337	2	journal	journal	PROPN
admet-1586	337	3	of	of	ADP
admet-1586	337	4	pharmaceutical	pharmaceutical	PROPN
admet-1586	337	5	sciences	science	NOUN
admet-1586	337	6	75	75	NUM
admet-1586	337	7	(	(	PUNCT
admet-1586	337	8	2015	2015	NUM
admet-1586	337	9	)	)	PUNCT
admet-1586	337	10	91	91	NUM
admet-1586	337	11	-	-	SYM
admet-1586	337	12	100	100	NUM
admet-1586	337	13	.	.	PUNCT
admet-1586	338	1	https://doi.org/10.1016/j.ejps.2015.03.009	https://doi.org/10.1016/j.ejps.2015.03.009	X
admet-1586	338	2	.	.	PUNCT
admet-1586	339	1	[	[	X
admet-1586	339	2	28	28	NUM
admet-1586	339	3	]	]	X
admet-1586	339	4	k.	k.	PROPN
admet-1586	339	5	holzapfel	holzapfel	PROPN
admet-1586	339	6	,	,	PUNCT
admet-1586	339	7	j.	j.	PROPN
admet-1586	339	8	liu	liu	PROPN
admet-1586	339	9	,	,	PUNCT
admet-1586	339	10	t.	t.	PROPN
admet-1586	339	11	rades	rades	PROPN
admet-1586	339	12	,	,	PUNCT
admet-1586	339	13	c.s	c.s	PROPN
admet-1586	339	14	.	.	PROPN
admet-1586	339	15	leopold	leopold	PROPN
admet-1586	339	16	.	.	PUNCT
admet-1586	340	1	(	(	PUNCT
admet-1586	340	2	co-)amorphization	co-)amorphization	NOUN
admet-1586	340	3	of	of	ADP
admet-1586	340	4	enantiomers	enantiomer	NOUN
admet-1586	340	5	investigation	investigation	NOUN
admet-1586	340	6	of	of	ADP
admet-1586	340	7	the	the	DET
admet-1586	340	8	amorphization	amorphization	NOUN
admet-1586	340	9	process	process	NOUN
admet-1586	340	10	,	,	PUNCT
admet-1586	340	11	the	the	DET
admet-1586	340	12	physical	physical	ADJ
admet-1586	340	13	stability	stability	NOUN
admet-1586	340	14	and	and	CCONJ
admet-1586	340	15	the	the	DET
admet-1586	340	16	dissolution	dissolution	ADJ
admet-1586	340	17	behavior	behavior	NOUN
admet-1586	340	18	.	.	PUNCT
admet-1586	341	1	international	international	ADJ
admet-1586	341	2	journal	journal	PROPN
admet-1586	341	3	of	of	ADP
admet-1586	341	4	pharmaceutics	pharmaceutic	NOUN
admet-1586	341	5	616	616	NUM
admet-1586	341	6	(	(	PUNCT
admet-1586	341	7	2022	2022	NUM
admet-1586	341	8	)	)	PUNCT
admet-1586	341	9	121552	121552	NUM
admet-1586	341	10	.	.	PUNCT
admet-1586	342	1	https://doi.org/10.1016/j.ijpharm.2022.121552	https://doi.org/10.1016/j.ijpharm.2022.121552	NOUN
admet-1586	342	2	.	.	PUNCT
admet-1586	343	1	[	[	X
admet-1586	343	2	29	29	NUM
admet-1586	343	3	]	]	X
admet-1586	343	4	y.	y.	PROPN
admet-1586	343	5	li	li	PROPN
admet-1586	343	6	,	,	PUNCT
admet-1586	343	7	a.k.p	a.k.p	NOUN
admet-1586	343	8	.	.	PUNCT
admet-1586	344	1	mann	mann	PROPN
admet-1586	344	2	,	,	PUNCT
admet-1586	344	3	d.	d.	PROPN
admet-1586	344	4	zhang	zhang	PROPN
admet-1586	344	5	,	,	PUNCT
admet-1586	344	6	z.	z.	PROPN
admet-1586	344	7	yang	yang	PROPN
admet-1586	344	8	.	.	PUNCT
admet-1586	345	1	processing	processing	NOUN
admet-1586	345	2	impact	impact	NOUN
admet-1586	345	3	on	on	ADP
admet-1586	345	4	in	in	ADP
admet-1586	345	5	vitro	vitro	X
admet-1586	345	6	and	and	CCONJ
admet-1586	345	7	in	in	ADP
admet-1586	345	8	vivo	vivo	ADJ
admet-1586	345	9	performance	performance	NOUN
admet-1586	345	10	of	of	ADP
admet-1586	345	11	solid	solid	ADJ
admet-1586	345	12	dispersionsa	dispersionsa	ADJ
admet-1586	345	13	comparison	comparison	NOUN
admet-1586	345	14	between	between	ADP
admet-1586	345	15	hot	hot	ADJ
admet-1586	345	16	-	-	PUNCT
admet-1586	345	17	melt	melt	NOUN
admet-1586	345	18	extrusion	extrusion	NOUN
admet-1586	345	19	and	and	CCONJ
admet-1586	345	20	spray	spray	VERB
admet-1586	345	21	drying	dry	VERB
admet-1586	345	22	.	.	PUNCT
admet-1586	346	1	pharmaceutics	pharmaceutic	NOUN
admet-1586	346	2	13	13	NUM
admet-1586	346	3	(	(	PUNCT
admet-1586	346	4	2021	2021	NUM
admet-1586	346	5	)	)	PUNCT
admet-1586	346	6	1307	1307	NUM
admet-1586	346	7	.	.	PUNCT
admet-1586	347	1	https://doi.org/10.3390/pharmaceutics13081307	https://doi.org/10.3390/pharmaceutics13081307	NOUN
admet-1586	347	2	.	.	PUNCT
admet-1586	348	1	[	[	X
admet-1586	348	2	30	30	NUM
admet-1586	348	3	]	]	X
admet-1586	348	4	v.r	v.r	PROPN
admet-1586	348	5	.	.	PROPN
admet-1586	348	6	kallakunta	kallakunta	PROPN
admet-1586	348	7	,	,	PUNCT
admet-1586	348	8	s.	s.	PROPN
admet-1586	348	9	sarabu	sarabu	PROPN
admet-1586	348	10	,	,	PUNCT
admet-1586	348	11	s.	s.	PROPN
admet-1586	348	12	bandari	bandari	PROPN
admet-1586	348	13	,	,	PUNCT
admet-1586	348	14	a.	a.	NOUN
admet-1586	348	15	batra	batra	PROPN
admet-1586	348	16	,	,	PUNCT
admet-1586	348	17	v.	v.	PROPN
admet-1586	348	18	bi	bi	PROPN
admet-1586	348	19	,	,	PUNCT
admet-1586	348	20	t.	t.	PROPN
admet-1586	348	21	durig	durig	PROPN
admet-1586	348	22	,	,	PUNCT
admet-1586	348	23	m.a	m.a	PROPN
admet-1586	348	24	.	.	PROPN
admet-1586	348	25	repka	repka	PROPN
admet-1586	348	26	.	.	PUNCT
admet-1586	349	1	stable	stable	ADJ
admet-1586	349	2	amorphous	amorphous	ADJ
admet-1586	349	3	solid	solid	ADJ
admet-1586	349	4	dispersions	dispersion	NOUN
admet-1586	349	5	of	of	ADP
admet-1586	349	6	fenofibrate	fenofibrate	NOUN
admet-1586	349	7	using	use	VERB
admet-1586	349	8	hot	hot	ADJ
admet-1586	349	9	melt	melt	NOUN
admet-1586	349	10	extrusion	extrusion	NOUN
admet-1586	349	11	technology	technology	NOUN
admet-1586	349	12	:	:	PUNCT
admet-1586	349	13	effect	effect	NOUN
admet-1586	349	14	of	of	ADP
admet-1586	349	15	formulation	formulation	NOUN
admet-1586	349	16	and	and	CCONJ
admet-1586	349	17	process	process	NOUN
admet-1586	349	18	parameters	parameter	NOUN
admet-1586	349	19	for	for	ADP
admet-1586	349	20	a	a	DET
admet-1586	349	21	low	low	ADJ
admet-1586	349	22	glass	glass	NOUN
admet-1586	349	23	transition	transition	NOUN
admet-1586	349	24	temperature	temperature	NOUN
admet-1586	349	25	drug	drug	NOUN
admet-1586	349	26	.	.	PUNCT
admet-1586	350	1	journal	journal	PROPN
admet-1586	350	2	of	of	ADP
admet-1586	350	3	drug	drug	NOUN
admet-1586	350	4	delivery	delivery	NOUN
admet-1586	350	5	science	science	NOUN
admet-1586	350	6	and	and	CCONJ
admet-1586	350	7	technology	technology	NOUN
admet-1586	350	8	58	58	NUM
admet-1586	350	9	(	(	PUNCT
admet-1586	350	10	2020	2020	NUM
admet-1586	350	11	)	)	PUNCT
admet-1586	350	12	101395	101395	NUM
admet-1586	350	13	.	.	PUNCT
admet-1586	351	1	https://doi.org/10.1016/j.jddst.2019.101395	https://doi.org/10.1016/j.jddst.2019.101395	NOUN
admet-1586	351	2	.	.	PUNCT
admet-1586	352	1	[	[	X
admet-1586	352	2	31	31	NUM
admet-1586	352	3	]	]	PUNCT
admet-1586	352	4	h.	h.	PROPN
admet-1586	352	5	ueda	ueda	PROPN
admet-1586	352	6	,	,	PUNCT
admet-1586	352	7	y.	y.	PROPN
admet-1586	352	8	ida	ida	PROPN
admet-1586	352	9	,	,	PUNCT
admet-1586	352	10	k.	k.	PROPN
admet-1586	352	11	kadota	kadota	PROPN
admet-1586	352	12	,	,	PUNCT
admet-1586	352	13	y.	y.	PROPN
admet-1586	352	14	tozuka	tozuka	PROPN
admet-1586	352	15	.	.	PUNCT
admet-1586	353	1	raman	raman	NOUN
admet-1586	353	2	mapping	mapping	NOUN
admet-1586	353	3	for	for	ADP
admet-1586	353	4	kinetic	kinetic	ADJ
admet-1586	353	5	analysis	analysis	NOUN
admet-1586	353	6	of	of	ADP
admet-1586	353	7	crystallization	crystallization	NOUN
admet-1586	353	8	of	of	ADP
admet-1586	353	9	amorphous	amorphous	ADJ
admet-1586	353	10	drug	drug	NOUN
admet-1586	353	11	based	base	VERB
admet-1586	353	12	on	on	ADP
admet-1586	353	13	distributional	distributional	ADJ
admet-1586	353	14	images	image	NOUN
admet-1586	353	15	.	.	PUNCT
admet-1586	354	1	international	international	ADJ
admet-1586	354	2	journal	journal	PROPN
admet-1586	354	3	of	of	ADP
admet-1586	354	4	pharmaceutics	pharmaceutic	NOUN
admet-1586	354	5	462	462	NUM
admet-1586	354	6	(	(	PUNCT
admet-1586	354	7	2014	2014	NUM
admet-1586	354	8	)	)	PUNCT
admet-1586	354	9	115	115	NUM
admet-1586	354	10	-	-	SYM
admet-1586	354	11	22	22	NUM
admet-1586	354	12	.	.	PUNCT
admet-1586	355	1	https://doi.org/10.1016/j.ijpharm.2013.12.025	https://doi.org/10.1016/j.ijpharm.2013.12.025	NOUN
admet-1586	355	2	.	.	PUNCT
admet-1586	356	1	[	[	X
admet-1586	356	2	32	32	NUM
admet-1586	356	3	]	]	PUNCT
admet-1586	356	4	j.	j.	PROPN
admet-1586	356	5	lu	lu	PROPN
admet-1586	356	6	,	,	PUNCT
admet-1586	356	7	s.	s.	PROPN
admet-1586	356	8	obara	obara	PROPN
admet-1586	356	9	,	,	PUNCT
admet-1586	356	10	f.	f.	PROPN
admet-1586	356	11	liu	liu	PROPN
admet-1586	356	12	,	,	PUNCT
admet-1586	356	13	w.	w.	PROPN
admet-1586	356	14	fu	fu	PROPN
admet-1586	356	15	,	,	PUNCT
admet-1586	356	16	w.	w.	PROPN
admet-1586	356	17	zhang	zhang	PROPN
admet-1586	356	18	,	,	PUNCT
admet-1586	356	19	s.	s.	PROPN
admet-1586	356	20	kikuchi	kikuchi	PROPN
admet-1586	356	21	.	.	PUNCT
admet-1586	356	22	melt	melt	VERB
admet-1586	356	23	extrusion	extrusion	NOUN
admet-1586	356	24	for	for	ADP
admet-1586	356	25	a	a	DET
admet-1586	356	26	high	high	ADJ
admet-1586	356	27	melting	melting	NOUN
admet-1586	356	28	point	point	NOUN
admet-1586	356	29	compound	compound	NOUN
admet-1586	356	30	with	with	ADP
admet-1586	356	31	improved	improve	VERB
admet-1586	356	32	solubility	solubility	NOUN
admet-1586	356	33	and	and	CCONJ
admet-1586	356	34	sustained	sustained	ADJ
admet-1586	356	35	release	release	NOUN
admet-1586	356	36	.	.	PUNCT
admet-1586	357	1	aaps	aap	NOUN
admet-1586	357	2	pharmscitech	pharmscitech	VERB
admet-1586	357	3	19	19	NUM
admet-1586	357	4	(	(	PUNCT
admet-1586	357	5	2018	2018	NUM
admet-1586	357	6	)	)	PUNCT
admet-1586	357	7	358	358	NUM
admet-1586	357	8	-	-	SYM
admet-1586	357	9	370	370	NUM
admet-1586	357	10	.	.	PUNCT
admet-1586	358	1	https://doi.org/10.1208/s12249-017-0846-6	https://doi.org/10.1208/s12249-017-0846-6	NUM
admet-1586	358	2	.	.	PUNCT
admet-1586	359	1	https://doi.org/10.1016/j.xphs.2020.08.007	https://doi.org/10.1016/j.xphs.2020.08.007	PROPN
admet-1586	359	2	https://doi.org/10.3390/pharmaceutics13030353	https://doi.org/10.3390/pharmaceutics13030353	PROPN
admet-1586	359	3	https://doi.org/10.1016/j.ijpharm.2018.12.086	https://doi.org/10.1016/j.ijpharm.2018.12.086	VERB
admet-1586	359	4	https://doi.org/10.1016/j.ejps.2017.12.029	https://doi.org/10.1016/j.ejps.2017.12.029	NOUN
admet-1586	359	5	https://doi.org/10.1208/s12249-018-1164-3	https://doi.org/10.1208/s12249-018-1164-3	NUM
admet-1586	359	6	https://doi.org/10.1016/j.ejpb.2019.12.002	https://doi.org/10.1016/j.ejpb.2019.12.002	NOUN
admet-1586	359	7	https://doi.org/10.1021/acs.molpharmaceut.7b00338	https://doi.org/10.1021/acs.molpharmaceut.7b00338	PROPN
admet-1586	359	8	https://doi.org/10.1016/j.ejpb.2009.04.006	https://doi.org/10.1016/j.ejpb.2009.04.006	NOUN
admet-1586	359	9	https://doi.org/10.1016/j.ejpb.2013.09.010	https://doi.org/10.1016/j.ejpb.2013.09.010	NOUN
admet-1586	359	10	https://doi.org/10.1016/j.ejps.2015.03.009	https://doi.org/10.1016/j.ejps.2015.03.009	NOUN
admet-1586	359	11	https://doi.org/10.1016/j.ijpharm.2022.121552	https://doi.org/10.1016/j.ijpharm.2022.121552	ADJ
admet-1586	359	12	https://doi.org/10.3390/pharmaceutics13081307	https://doi.org/10.3390/pharmaceutics13081307	NOUN
admet-1586	359	13	https://doi.org/10.1016/j.jddst.2019.101395	https://doi.org/10.1016/j.jddst.2019.101395	ADJ
admet-1586	359	14	https://doi.org/10.1016/j.ijpharm.2013.12.025	https://doi.org/10.1016/j.ijpharm.2013.12.025	NOUN
admet-1586	359	15	https://doi.org/10.1208/s12249-017-0846-6	https://doi.org/10.1208/s12249-017-0846-6	NUM
admet-1586	359	16	admet	admet	PROPN
admet-1586	359	17	&	&	CCONJ
admet-1586	359	18	dmpk	dmpk	PROPN
admet-1586	359	19	11(3	11(3	NUM
admet-1586	359	20	)	)	PUNCT
admet-1586	359	21	(	(	PUNCT
admet-1586	359	22	2023	2023	NUM
admet-1586	359	23	)	)	PUNCT
admet-1586	359	24	373	373	NUM
admet-1586	359	25	-	-	SYM
admet-1586	359	26	385	385	NUM
admet-1586	359	27	dissolution	dissolution	NOUN
admet-1586	359	28	-	-	PUNCT
admet-1586	359	29	permeation	permeation	NOUN
admet-1586	359	30	of	of	ADP
admet-1586	359	31	hot	hot	ADJ
admet-1586	359	32	-	-	PUNCT
admet-1586	359	33	melt	melt	NOUN
admet-1586	359	34	extruded	extrude	VERB
admet-1586	359	35	asd	asd	NOUN
admet-1586	359	36	doi	doi	PROPN
admet-1586	359	37	:	:	PUNCT
admet-1586	359	38	https://doi.org/10.5599/admet.1586	https://doi.org/10.5599/admet.1586	NOUN
admet-1586	359	39	385	385	NUM
admet-1586	359	40	[	[	SYM
admet-1586	359	41	33	33	NUM
admet-1586	359	42	]	]	PUNCT
admet-1586	359	43	k.	k.	PROPN
admet-1586	359	44	kawakami	kawakami	PROPN
admet-1586	359	45	.	.	PUNCT
admet-1586	360	1	crystallization	crystallization	NOUN
admet-1586	360	2	tendency	tendency	NOUN
admet-1586	360	3	of	of	ADP
admet-1586	360	4	pharmaceutical	pharmaceutical	ADJ
admet-1586	360	5	glasses	glass	NOUN
admet-1586	360	6	:	:	PUNCT
admet-1586	360	7	relevance	relevance	NOUN
admet-1586	360	8	to	to	ADP
admet-1586	360	9	compound	compound	NOUN
admet-1586	360	10	properties	property	NOUN
admet-1586	360	11	,	,	PUNCT
admet-1586	360	12	impact	impact	NOUN
admet-1586	360	13	of	of	ADP
admet-1586	360	14	formulation	formulation	NOUN
admet-1586	360	15	process	process	NOUN
admet-1586	360	16	,	,	PUNCT
admet-1586	360	17	and	and	CCONJ
admet-1586	360	18	implications	implication	NOUN
admet-1586	360	19	for	for	ADP
admet-1586	360	20	design	design	NOUN
admet-1586	360	21	of	of	ADP
admet-1586	360	22	amorphous	amorphous	ADJ
admet-1586	360	23	solid	solid	ADJ
admet-1586	360	24	dispersions	dispersion	NOUN
admet-1586	360	25	.	.	PUNCT
admet-1586	361	1	pharmaceutics	pharmaceutic	NOUN
admet-1586	361	2	11	11	NUM
admet-1586	361	3	(	(	PUNCT
admet-1586	361	4	2019	2019	NUM
admet-1586	361	5	)	)	PUNCT
admet-1586	361	6	e202	e202	PROPN
admet-1586	361	7	.	.	PUNCT
admet-1586	361	8	https://doi.org/10.3390/pharmaceutics11050202	https://doi.org/10.3390/pharmaceutics11050202	PROPN
admet-1586	361	9	.	.	PUNCT
admet-1586	362	1	[	[	X
admet-1586	362	2	34	34	NUM
admet-1586	362	3	]	]	X
admet-1586	362	4	k.	k.	PROPN
admet-1586	362	5	kawakami	kawakami	PROPN
admet-1586	362	6	,	,	PUNCT
admet-1586	362	7	t.	t.	PROPN
admet-1586	362	8	harada	harada	PROPN
admet-1586	362	9	,	,	PUNCT
admet-1586	362	10	k.	k.	PROPN
admet-1586	362	11	miura	miura	PROPN
admet-1586	362	12	,	,	PUNCT
admet-1586	362	13	y.	y.	PROPN
admet-1586	362	14	yoshihashi	yoshihashi	PROPN
admet-1586	362	15	,	,	PUNCT
admet-1586	362	16	e.	e.	PROPN
admet-1586	362	17	yonemochi	yonemochi	PROPN
admet-1586	362	18	,	,	PUNCT
admet-1586	362	19	k.	k.	PROPN
admet-1586	362	20	terada	terada	PROPN
admet-1586	362	21	,	,	PUNCT
admet-1586	362	22	h.	h.	PROPN
admet-1586	362	23	moriyama	moriyama	PROPN
admet-1586	362	24	.	.	PUNCT
admet-1586	363	1	relationship	relationship	NOUN
admet-1586	363	2	between	between	ADP
admet-1586	363	3	crystallization	crystallization	NOUN
admet-1586	363	4	tendencies	tendency	NOUN
admet-1586	363	5	during	during	ADP
admet-1586	363	6	cooling	cool	VERB
admet-1586	363	7	from	from	ADP
admet-1586	363	8	melt	melt	NOUN
admet-1586	363	9	and	and	CCONJ
admet-1586	363	10	isothermal	isothermal	ADJ
admet-1586	363	11	storage	storage	NOUN
admet-1586	363	12	:	:	PUNCT
admet-1586	363	13	toward	toward	ADP
admet-1586	363	14	a	a	DET
admet-1586	363	15	general	general	ADJ
admet-1586	363	16	understanding	understanding	NOUN
admet-1586	363	17	of	of	ADP
admet-1586	363	18	physical	physical	ADJ
admet-1586	363	19	stability	stability	NOUN
admet-1586	363	20	of	of	ADP
admet-1586	363	21	pharmaceutical	pharmaceutical	ADJ
admet-1586	363	22	glasses	glass	NOUN
admet-1586	363	23	.	.	PUNCT
admet-1586	364	1	molecular	molecular	ADJ
admet-1586	364	2	pharmaceutics	pharmaceutic	NOUN
admet-1586	364	3	11	11	NUM
admet-1586	364	4	(	(	PUNCT
admet-1586	364	5	2014	2014	NUM
admet-1586	364	6	)	)	PUNCT
admet-1586	364	7	1835	1835	NUM
admet-1586	364	8	-	-	SYM
admet-1586	364	9	1843	1843	NUM
admet-1586	364	10	.	.	PUNCT
admet-1586	365	1	https://doi.org/10.1021/mp400679	https://doi.org/10.1021/mp400679	NOUN
admet-1586	366	1	m.	m.	NOUN
admet-1586	366	2	[	[	X
admet-1586	366	3	35	35	NUM
admet-1586	366	4	]	]	X
admet-1586	366	5	j.h	j.h	PROPN
admet-1586	366	6	.	.	PROPN
admet-1586	366	7	fagerberg	fagerberg	PROPN
admet-1586	366	8	,	,	PUNCT
admet-1586	366	9	o.	o.	PROPN
admet-1586	366	10	tsinman	tsinman	NOUN
admet-1586	366	11	,	,	PUNCT
admet-1586	366	12	n.	n.	PROPN
admet-1586	366	13	sun	sun	PROPN
admet-1586	366	14	,	,	PUNCT
admet-1586	366	15	k.	k.	PROPN
admet-1586	366	16	tsinman	tsinman	PROPN
admet-1586	366	17	,	,	PUNCT
admet-1586	366	18	a.	a.	PROPN
admet-1586	366	19	avdeef	avdeef	PROPN
admet-1586	366	20	,	,	PUNCT
admet-1586	366	21	c.a	c.a	PROPN
admet-1586	366	22	.	.	PROPN
admet-1586	366	23	bergström	bergström	PROPN
admet-1586	366	24	.	.	PUNCT
admet-1586	367	1	dissolution	dissolution	NOUN
admet-1586	367	2	rate	rate	NOUN
admet-1586	367	3	and	and	CCONJ
admet-1586	367	4	apparent	apparent	ADJ
admet-1586	367	5	solubility	solubility	NOUN
admet-1586	367	6	of	of	ADP
admet-1586	367	7	poorly	poorly	ADV
admet-1586	367	8	soluble	soluble	ADJ
admet-1586	367	9	drugs	drug	NOUN
admet-1586	367	10	in	in	ADP
admet-1586	367	11	biorelevant	biorelevant	ADJ
admet-1586	367	12	dissolution	dissolution	NOUN
admet-1586	367	13	media	medium	NOUN
admet-1586	367	14	.	.	PUNCT
admet-1586	368	1	molecular	molecular	ADJ
admet-1586	368	2	pharmaceutics	pharmaceutic	NOUN
admet-1586	368	3	7	7	NUM
admet-1586	368	4	(	(	PUNCT
admet-1586	368	5	2010	2010	NUM
admet-1586	368	6	)	)	PUNCT
admet-1586	368	7	1419	1419	NUM
admet-1586	368	8	-	-	SYM
admet-1586	368	9	1430	1430	NUM
admet-1586	368	10	.	.	PUNCT
admet-1586	369	1	https://doi.org/10.1021/mp100049	https://doi.org/10.1021/mp100049	DET
admet-1586	369	2	m.	m.	NOUN
admet-1586	369	3	[	[	X
admet-1586	369	4	36	36	NUM
admet-1586	369	5	]	]	X
admet-1586	369	6	a.l	a.l	PROPN
admet-1586	369	7	.	.	PROPN
admet-1586	369	8	sarode	sarode	PROPN
admet-1586	369	9	,	,	PUNCT
admet-1586	369	10	h.	h.	PROPN
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admet-1586	369	12	,	,	PUNCT
admet-1586	369	13	n.	n.	NOUN
admet-1586	369	14	shah	shah	PROPN
admet-1586	369	15	,	,	PUNCT
admet-1586	369	16	w.	w.	PROPN
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admet-1586	369	18	,	,	PUNCT
admet-1586	369	19	h.	h.	PROPN
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admet-1586	369	21	.	.	PUNCT
admet-1586	370	1	hot	hot	ADJ
admet-1586	370	2	melt	melt	NOUN
admet-1586	370	3	extrusion	extrusion	NOUN
admet-1586	370	4	(	(	PUNCT
admet-1586	370	5	hme	hme	NOUN
admet-1586	370	6	)	)	PUNCT
admet-1586	370	7	for	for	ADP
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admet-1586	370	9	solid	solid	ADJ
admet-1586	370	10	dispersions	dispersion	NOUN
admet-1586	370	11	:	:	PUNCT
admet-1586	370	12	predictive	predictive	ADJ
admet-1586	370	13	tools	tool	NOUN
admet-1586	370	14	for	for	ADP
admet-1586	370	15	processing	processing	NOUN
admet-1586	370	16	and	and	CCONJ
admet-1586	370	17	impact	impact	NOUN
admet-1586	370	18	of	of	ADP
admet-1586	370	19	drug	drug	NOUN
admet-1586	370	20	-	-	PUNCT
admet-1586	370	21	polymer	polymer	NOUN
admet-1586	370	22	interactions	interaction	NOUN
admet-1586	370	23	on	on	ADP
admet-1586	370	24	supersaturation	supersaturation	NOUN
admet-1586	370	25	.	.	PUNCT
admet-1586	371	1	european	european	ADJ
admet-1586	371	2	journal	journal	PROPN
admet-1586	371	3	of	of	ADP
admet-1586	371	4	pharmaceutical	pharmaceutical	PROPN
admet-1586	371	5	sciences	science	NOUN
admet-1586	371	6	48	48	NUM
admet-1586	371	7	(	(	PUNCT
admet-1586	371	8	2013	2013	NUM
admet-1586	371	9	)	)	PUNCT
admet-1586	371	10	371	371	NUM
admet-1586	371	11	-	-	SYM
admet-1586	371	12	384	384	NUM
admet-1586	371	13	.	.	PUNCT
admet-1586	371	14	https://doi.org/10.1016/j.ejps.2012.12.012	https://doi.org/10.1016/j.ejps.2012.12.012	NOUN
admet-1586	371	15	.	.	PUNCT
admet-1586	372	1	[	[	X
admet-1586	372	2	37	37	NUM
admet-1586	372	3	]	]	X
admet-1586	372	4	m.j	m.j	PROPN
admet-1586	372	5	.	.	PROPN
admet-1586	372	6	jackson	jackson	PROPN
admet-1586	372	7	,	,	PUNCT
admet-1586	372	8	u.s	u.s	PROPN
admet-1586	372	9	.	.	PROPN
admet-1586	372	10	kestur	kestur	PROPN
admet-1586	372	11	,	,	PUNCT
admet-1586	372	12	m.a	m.a	PROPN
admet-1586	372	13	.	.	PROPN
admet-1586	372	14	hussain	hussain	PROPN
admet-1586	372	15	,	,	PUNCT
admet-1586	372	16	l.s	l.s	PROPN
admet-1586	372	17	.	.	PROPN
admet-1586	372	18	taylor	taylor	PROPN
admet-1586	372	19	.	.	PUNCT
admet-1586	372	20	dissolution	dissolution	PROPN
admet-1586	372	21	of	of	ADP
admet-1586	372	22	danazol	danazol	ADJ
admet-1586	372	23	amorphous	amorphous	ADJ
admet-1586	372	24	solid	solid	ADJ
admet-1586	372	25	dispersions	dispersion	NOUN
admet-1586	372	26	:	:	PUNCT
admet-1586	372	27	supersaturation	supersaturation	NOUN
admet-1586	372	28	and	and	CCONJ
admet-1586	372	29	phase	phase	NOUN
admet-1586	372	30	behavior	behavior	NOUN
admet-1586	372	31	as	as	ADP
admet-1586	372	32	a	a	DET
admet-1586	372	33	function	function	NOUN
admet-1586	372	34	of	of	ADP
admet-1586	372	35	drug	drug	NOUN
admet-1586	372	36	loading	loading	NOUN
admet-1586	372	37	and	and	CCONJ
admet-1586	372	38	polymer	polymer	NOUN
admet-1586	372	39	type	type	NOUN
admet-1586	372	40	.	.	PUNCT
admet-1586	373	1	molecular	molecular	ADJ
admet-1586	373	2	pharmaceutics	pharmaceutic	NOUN
admet-1586	373	3	13	13	NUM
admet-1586	373	4	(	(	PUNCT
admet-1586	373	5	2016	2016	NUM
admet-1586	373	6	)	)	PUNCT
admet-1586	373	7	223	223	NUM
admet-1586	373	8	-	-	SYM
admet-1586	373	9	231	231	NUM
admet-1586	373	10	.	.	PUNCT
admet-1586	374	1	https://doi.org/10.1021/acs.molpharmaceut.5b00652	https://doi.org/10.1021/acs.molpharmaceut.5b00652	X
admet-1586	374	2	.	.	PUNCT
admet-1586	375	1	[	[	X
admet-1586	375	2	38	38	NUM
admet-1586	375	3	]	]	PUNCT
admet-1586	375	4	k.	k.	PROPN
admet-1586	375	5	ueda	ueda	PROPN
admet-1586	375	6	,	,	PUNCT
admet-1586	375	7	s.s	s.s	PROPN
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admet-1586	375	9	hate	hate	PROPN
admet-1586	375	10	,	,	PUNCT
admet-1586	375	11	l.s	l.s	PROPN
admet-1586	375	12	.	.	PROPN
admet-1586	375	13	taylor	taylor	PROPN
admet-1586	375	14	.	.	PUNCT
admet-1586	376	1	impact	impact	NOUN
admet-1586	376	2	of	of	ADP
admet-1586	376	3	hypromellose	hypromellose	ADJ
admet-1586	376	4	acetate	acetate	NOUN
admet-1586	376	5	succinate	succinate	NOUN
admet-1586	376	6	grade	grade	NOUN
admet-1586	376	7	on	on	ADP
admet-1586	376	8	drug	drug	NOUN
admet-1586	376	9	amorphous	amorphous	ADJ
admet-1586	376	10	solubility	solubility	NOUN
admet-1586	376	11	and	and	CCONJ
admet-1586	376	12	in	in	ADP
admet-1586	376	13	vitro	vitro	X
admet-1586	376	14	membrane	membrane	NOUN
admet-1586	376	15	transport	transport	NOUN
admet-1586	376	16	.	.	PUNCT
admet-1586	377	1	journal	journal	NOUN
admet-1586	377	2	of	of	ADP
admet-1586	377	3	pharmaceutical	pharmaceutical	PROPN
admet-1586	377	4	sciences	science	NOUN
admet-1586	377	5	109	109	NUM
admet-1586	377	6	(	(	PUNCT
admet-1586	377	7	2020	2020	NUM
admet-1586	377	8	)	)	PUNCT
admet-1586	377	9	24642473	24642473	NUM
admet-1586	377	10	.	.	PUNCT
admet-1586	378	1	https://doi.org/10.1016/j.xphs.2020.04.014	https://doi.org/10.1016/j.xphs.2020.04.014	X
admet-1586	378	2	.	.	PUNCT
admet-1586	379	1	[	[	X
admet-1586	379	2	39	39	NUM
admet-1586	379	3	]	]	X
admet-1586	379	4	a.n	a.n	PROPN
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admet-1586	379	9	.	.	PROPN
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admet-1586	379	13	li	li	PROPN
admet-1586	379	14	.	.	PROPN
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admet-1586	379	17	hydroxypropyl	hydroxypropyl	ADJ
admet-1586	379	18	methylcellulose	methylcellulose	NOUN
admet-1586	379	19	acetate	acetate	NOUN
admet-1586	379	20	succinate	succinate	PROPN
admet-1586	379	21	critical	critical	ADJ
admet-1586	379	22	aggregation	aggregation	NOUN
admet-1586	379	23	concentration	concentration	NOUN
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admet-1586	379	26	supersaturation	supersaturation	NOUN
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admet-1586	380	3	18	18	NUM
admet-1586	380	4	(	(	PUNCT
admet-1586	380	5	2021	2021	NUM
admet-1586	380	6	)	)	PUNCT
admet-1586	380	7	42994309	42994309	NUM
admet-1586	380	8	.	.	PUNCT
admet-1586	381	1	https://doi.org/10.1021/acs.molpharmaceut.1c00372	https://doi.org/10.1021/acs.molpharmaceut.1c00372	X
admet-1586	381	2	.	.	PUNCT
admet-1586	382	1	[	[	X
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admet-1586	382	4	a.	a.	NOUN
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admet-1586	382	6	.	.	PUNCT
admet-1586	383	1	cocrystal	cocrystal	PROPN
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admet-1586	383	3	product	product	NOUN
admet-1586	383	4	analysis	analysis	NOUN
admet-1586	383	5	dual	dual	ADJ
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admet-1586	383	17	equations	equation	NOUN
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admet-1586	384	7	(	(	PUNCT
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admet-1586	384	9	)	)	PUNCT
admet-1586	384	10	218	218	NUM
admet-1586	384	11	.	.	PUNCT
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admet-1586	385	2	.	.	PUNCT
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admet-1586	387	1	this	this	DET
admet-1586	387	2	article	article	NOUN
admet-1586	387	3	is	be	AUX
admet-1586	387	4	an	an	DET
admet-1586	387	5	open	open	ADJ
admet-1586	387	6	-	-	PUNCT
admet-1586	387	7	access	access	NOUN
admet-1586	387	8	article	article	NOUN
admet-1586	387	9	distributed	distribute	VERB
admet-1586	387	10	under	under	ADP
admet-1586	387	11	the	the	DET
admet-1586	387	12	terms	term	NOUN
admet-1586	387	13	and	and	CCONJ
admet-1586	387	14	conditions	condition	NOUN
admet-1586	387	15	of	of	ADP
admet-1586	387	16	the	the	DET
admet-1586	387	17	creative	creative	ADJ
admet-1586	387	18	commons	common	NOUN
admet-1586	387	19	attribution	attribution	NOUN
admet-1586	387	20	license	license	NOUN
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admet-1586	387	25	https://doi.org/10.3390/pharmaceutics11050202	https://doi.org/10.3390/pharmaceutics11050202	PROPN
admet-1586	387	26	https://doi.org/10.1021/mp400679	https://doi.org/10.1021/mp400679	PROPN
admet-1586	387	27	m	m	VERB
admet-1586	387	28	https://doi.org/10.1021/mp100049	https://doi.org/10.1021/mp100049	NOUN
admet-1586	387	29	m	m	NOUN
admet-1586	387	30	https://doi.org/10.1016/j.ejps.2012.12.012	https://doi.org/10.1016/j.ejps.2012.12.012	NOUN
admet-1586	387	31	https://doi.org/10.1021/acs.molpharmaceut.5b00652	https://doi.org/10.1021/acs.molpharmaceut.5b00652	X
admet-1586	387	32	https://doi.org/10.1016/j.xphs.2020.04.014	https://doi.org/10.1016/j.xphs.2020.04.014	PROPN
admet-1586	387	33	https://doi.org/10.1021/acs.molpharmaceut.1c00372	https://doi.org/10.1021/acs.molpharmaceut.1c00372	VERB
admet-1586	387	34	https://doi.org/10.1016/j.ejps.2017.03.049	https://doi.org/10.1016/j.ejps.2017.03.049	PRON
admet-1586	387	35	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	NOUN