id	sid	tid	token	lemma	pos
admet-159	1	1	manuscript	manuscript	PROPN
admet-159	1	2	doi	doi	PROPN
admet-159	1	3	:	:	PUNCT
admet-159	1	4	10.5599	10.5599	NUM
admet-159	1	5	/	/	SYM
admet-159	1	6	admet.3.1.159	admet.3.1.159	NUM
admet-159	1	7	15	15	NUM
admet-159	1	8	admet	admet	X
admet-159	1	9	&	&	CCONJ
admet-159	1	10	dmpk	dmpk	PROPN
admet-159	1	11	3(1	3(1	NUM
admet-159	1	12	)	)	PUNCT
admet-159	1	13	(	(	PUNCT
admet-159	1	14	2015	2015	NUM
admet-159	1	15	)	)	PUNCT
admet-159	1	16	15	15	NUM
admet-159	1	17	-	-	SYM
admet-159	1	18	33	33	NUM
admet-159	1	19	;	;	PUNCT
admet-159	1	20	doi	doi	NOUN
admet-159	1	21	:	:	PUNCT
admet-159	1	22	10.5599	10.5599	NUM
admet-159	1	23	/	/	SYM
admet-159	1	24	admet.3.1.159	admet.3.1.159	NUM
admet-159	1	25	open	open	ADJ
admet-159	1	26	access	access	NOUN
admet-159	1	27	:	:	PUNCT
admet-159	1	28	issn	issn	PROPN
admet-159	1	29	:	:	PUNCT
admet-159	1	30	1848	1848	NUM
admet-159	1	31	-	-	SYM
admet-159	1	32	7718	7718	NUM
admet-159	1	33	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-159	1	34	original	original	ADJ
admet-159	1	35	scientific	scientific	ADJ
admet-159	1	36	paper	paper	NOUN
admet-159	1	37	expression	expression	NOUN
admet-159	1	38	and	and	CCONJ
admet-159	1	39	transport	transport	NOUN
admet-159	1	40	of	of	ADP
admet-159	1	41	-synuclein	-synuclein	PROPN
admet-159	1	42	at	at	ADP
admet-159	1	43	the	the	DET
admet-159	1	44	bloodcerebrospinal	bloodcerebrospinal	ADJ
admet-159	1	45	fluid	fluid	ADJ
admet-159	1	46	barrier	barrier	NOUN
admet-159	1	47	and	and	CCONJ
admet-159	1	48	effects	effect	NOUN
admet-159	1	49	of	of	ADP
admet-159	1	50	manganese	manganese	ADJ
admet-159	1	51	exposure	exposure	NOUN
admet-159	1	52	christopher	christopher	PROPN
admet-159	1	53	a.	a.	PROPN
admet-159	1	54	bates1	bates1	PROPN
admet-159	1	55	,	,	PUNCT
admet-159	1	56	sherleen	sherleen	VERB
admet-159	1	57	fu1	fu1	PROPN
admet-159	1	58	,	,	PUNCT
admet-159	1	59	daniel	daniel	PROPN
admet-159	1	60	ysselstein2	ysselstein2	PROPN
admet-159	1	61	,	,	PUNCT
admet-159	1	62	jean	jean	PROPN
admet-159	1	63	-	-	PUNCT
admet-159	1	64	christophe	christophe	PROPN
admet-159	1	65	rochet2	rochet2	PROPN
admet-159	1	66	,	,	PUNCT
admet-159	1	67	and	and	CCONJ
admet-159	1	68	wei	wei	PROPN
admet-159	1	69	zheng1	zheng1	PROPN
admet-159	1	70	*	*	PROPN
admet-159	1	71	1	1	NUM
admet-159	1	72	school	school	NOUN
admet-159	1	73	of	of	ADP
admet-159	1	74	health	health	NOUN
admet-159	1	75	sciences	sciences	PROPN
admet-159	1	76	,	,	PUNCT
admet-159	1	77	purdue	purdue	PROPN
admet-159	1	78	university	university	NOUN
admet-159	1	79	,	,	PUNCT
admet-159	1	80	west	west	PROPN
admet-159	1	81	lafayette	lafayette	PROPN
admet-159	1	82	,	,	PUNCT
admet-159	1	83	in	in	ADP
admet-159	1	84	47907	47907	NUM
admet-159	1	85	2	2	NUM
admet-159	1	86	department	department	NOUN
admet-159	1	87	of	of	ADP
admet-159	1	88	molecular	molecular	ADJ
admet-159	1	89	pharmacology	pharmacology	NOUN
admet-159	1	90	and	and	CCONJ
admet-159	1	91	medicinal	medicinal	ADJ
admet-159	1	92	chemistry	chemistry	NOUN
admet-159	1	93	,	,	PUNCT
admet-159	1	94	purdue	purdue	PROPN
admet-159	1	95	university	university	NOUN
admet-159	1	96	,	,	PUNCT
admet-159	1	97	west	west	PROPN
admet-159	1	98	lafayette	lafayette	PROPN
admet-159	1	99	,	,	PUNCT
admet-159	1	100	in	in	ADP
admet-159	1	101	47907	47907	NUM
admet-159	1	102	*	*	PUNCT
admet-159	1	103	corresponding	correspond	VERB
admet-159	1	104	author	author	NOUN
admet-159	1	105	:	:	PUNCT
admet-159	1	106	e	e	NOUN
admet-159	1	107	-	-	NOUN
admet-159	1	108	mail	mail	NOUN
admet-159	1	109	:	:	PUNCT
admet-159	1	110	wzheng@purdue.edu	wzheng@purdue.edu	PROPN
admet-159	1	111	;	;	PUNCT
admet-159	1	112	tel	tel	PROPN
admet-159	1	113	.	.	PROPN
admet-159	1	114	:	:	PUNCT
admet-159	2	1	(	(	PUNCT
admet-159	2	2	765	765	NUM
admet-159	2	3	)	)	PUNCT
admet-159	2	4	496	496	NUM
admet-159	2	5	-	-	SYM
admet-159	2	6	6447	6447	NUM
admet-159	2	7	;	;	PUNCT
admet-159	2	8	fax	fax	NOUN
admet-159	2	9	:	:	PUNCT
admet-159	2	10	(	(	PUNCT
admet-159	2	11	765	765	NUM
admet-159	2	12	)	)	PUNCT
admet-159	2	13	496	496	NUM
admet-159	2	14	-	-	PUNCT
admet-159	2	15	1377	1377	NUM
admet-159	2	16	received	receive	VERB
admet-159	2	17	:	:	PUNCT
admet-159	2	18	january	january	PROPN
admet-159	2	19	19	19	NUM
admet-159	2	20	,	,	PUNCT
admet-159	2	21	2015	2015	NUM
admet-159	2	22	;	;	PUNCT
admet-159	2	23	revised	revise	VERB
admet-159	2	24	:	:	PUNCT
admet-159	2	25	march	march	PROPN
admet-159	2	26	16	16	NUM
admet-159	2	27	,	,	PUNCT
admet-159	2	28	2015	2015	NUM
admet-159	2	29	;	;	PUNCT
admet-159	2	30	published	publish	VERB
admet-159	2	31	:	:	PUNCT
admet-159	2	32	march	march	PROPN
admet-159	2	33	31	31	NUM
admet-159	2	34	,	,	PUNCT
admet-159	2	35	2015	2015	NUM
admet-159	2	36	abstract	abstract	NOUN
admet-159	2	37	the	the	DET
admet-159	2	38	choroid	choroid	NOUN
admet-159	2	39	plexus	plexus	NOUN
admet-159	2	40	maintains	maintain	VERB
admet-159	2	41	the	the	DET
admet-159	2	42	homeostasis	homeostasis	NOUN
admet-159	2	43	of	of	ADP
admet-159	2	44	critical	critical	ADJ
admet-159	2	45	molecules	molecule	NOUN
admet-159	2	46	in	in	ADP
admet-159	2	47	the	the	DET
admet-159	2	48	brain	brain	NOUN
admet-159	2	49	by	by	ADP
admet-159	2	50	regulating	regulate	VERB
admet-159	2	51	their	their	PRON
admet-159	2	52	transport	transport	NOUN
admet-159	2	53	between	between	ADP
admet-159	2	54	the	the	DET
admet-159	2	55	blood	blood	NOUN
admet-159	2	56	and	and	CCONJ
admet-159	2	57	cerebrospinal	cerebrospinal	ADJ
admet-159	2	58	fluid	fluid	NOUN
admet-159	2	59	(	(	PUNCT
admet-159	2	60	csf	csf	NOUN
admet-159	2	61	)	)	PUNCT
admet-159	2	62	.	.	PUNCT
admet-159	3	1	the	the	DET
admet-159	3	2	current	current	ADJ
admet-159	3	3	study	study	NOUN
admet-159	3	4	was	be	AUX
admet-159	3	5	designed	design	VERB
admet-159	3	6	to	to	PART
admet-159	3	7	investigate	investigate	VERB
admet-159	3	8	the	the	DET
admet-159	3	9	potential	potential	ADJ
admet-159	3	10	role	role	NOUN
admet-159	3	11	of	of	ADP
admet-159	3	12	the	the	DET
admet-159	3	13	blood	blood	NOUN
admet-159	3	14	-	-	PUNCT
admet-159	3	15	csf	csf	ADJ
admet-159	3	16	barrier	barrier	NOUN
admet-159	3	17	(	(	PUNCT
admet-159	3	18	bcsfb	bcsfb	PROPN
admet-159	3	19	)	)	PUNCT
admet-159	3	20	in	in	ADP
admet-159	3	21	α	α	NOUN
admet-159	3	22	-	-	PUNCT
admet-159	3	23	synuclein	synuclein	NOUN
admet-159	3	24	(	(	PUNCT
admet-159	3	25	a	a	PROPN
admet-159	3	26	-	-	PUNCT
admet-159	3	27	syn	syn	NOUN
admet-159	3	28	)	)	PUNCT
admet-159	3	29	transport	transport	NOUN
admet-159	3	30	in	in	ADP
admet-159	3	31	the	the	DET
admet-159	3	32	brain	brain	NOUN
admet-159	3	33	as	as	SCONJ
admet-159	3	34	affected	affect	VERB
admet-159	3	35	by	by	ADP
admet-159	3	36	exposure	exposure	NOUN
admet-159	3	37	to	to	ADP
admet-159	3	38	manganese	manganese	NOUN
admet-159	3	39	(	(	PUNCT
admet-159	3	40	mn	mn	PROPN
admet-159	3	41	)	)	PUNCT
admet-159	3	42	,	,	PUNCT
admet-159	3	43	the	the	DET
admet-159	3	44	toxic	toxic	ADJ
admet-159	3	45	metal	metal	NOUN
admet-159	3	46	implicated	implicate	VERB
admet-159	3	47	in	in	ADP
admet-159	3	48	parkinsonian	parkinsonian	ADJ
admet-159	3	49	disorders	disorder	NOUN
admet-159	3	50	.	.	PUNCT
admet-159	4	1	immunohistochemistry	immunohistochemistry	PROPN
admet-159	4	2	was	be	AUX
admet-159	4	3	used	use	VERB
admet-159	4	4	to	to	PART
admet-159	4	5	identify	identify	VERB
admet-159	4	6	intracellular	intracellular	ADJ
admet-159	4	7	a	a	PRON
admet-159	4	8	-	-	PUNCT
admet-159	4	9	syn	syn	NOUN
admet-159	4	10	expression	expression	NOUN
admet-159	4	11	at	at	ADP
admet-159	4	12	the	the	DET
admet-159	4	13	bcsfb	bcsfb	NOUN
admet-159	4	14	.	.	PUNCT
admet-159	5	1	quantitative	quantitative	ADJ
admet-159	5	2	realtime	realtime	ADJ
admet-159	5	3	pcr	pcr	NOUN
admet-159	5	4	was	be	AUX
admet-159	5	5	used	use	VERB
admet-159	5	6	to	to	PART
admet-159	5	7	quantify	quantify	VERB
admet-159	5	8	the	the	DET
admet-159	5	9	change	change	NOUN
admet-159	5	10	in	in	ADP
admet-159	5	11	a	a	DET
admet-159	5	12	-	-	PUNCT
admet-159	5	13	syn	syn	NOUN
admet-159	5	14	mrna	mrna	PROPN
admet-159	5	15	expression	expression	NOUN
admet-159	5	16	following	follow	VERB
admet-159	5	17	mn	mn	PROPN
admet-159	5	18	treatments	treatment	NOUN
admet-159	5	19	at	at	ADP
admet-159	5	20	the	the	DET
admet-159	5	21	bcsfb	bcsfb	NOUN
admet-159	5	22	in	in	ADP
admet-159	5	23	vitro	vitro	X
admet-159	5	24	.	.	PUNCT
admet-159	6	1	elisa	elisa	PROPN
admet-159	6	2	was	be	AUX
admet-159	6	3	used	use	VERB
admet-159	6	4	to	to	PART
admet-159	6	5	quantify	quantify	VERB
admet-159	6	6	a	a	DET
admet-159	6	7	-	-	PUNCT
admet-159	6	8	syn	syn	NOUN
admet-159	6	9	levels	level	NOUN
admet-159	6	10	following	follow	VERB
admet-159	6	11	in	in	ADP
admet-159	6	12	vivo	vivo	NOUN
admet-159	6	13	and	and	CCONJ
admet-159	6	14	in	in	ADP
admet-159	6	15	vitro	vitro	X
admet-159	6	16	treatments	treatment	NOUN
admet-159	6	17	of	of	ADP
admet-159	6	18	mn	mn	PROPN
admet-159	6	19	,	,	PUNCT
admet-159	6	20	copper	copper	NOUN
admet-159	6	21	(	(	PUNCT
admet-159	6	22	cu	cu	PROPN
admet-159	6	23	)	)	PUNCT
admet-159	6	24	,	,	PUNCT
admet-159	6	25	and/or	and/or	CCONJ
admet-159	6	26	external	external	ADJ
admet-159	6	27	a	a	PROPN
admet-159	6	28	-	-	PUNCT
admet-159	6	29	syn	syn	PROPN
admet-159	6	30	.	.	PROPN
admet-159	6	31	thioflavin	thioflavin	PROPN
admet-159	6	32	-	-	PUNCT
admet-159	6	33	t	t	PROPN
admet-159	6	34	assay	assay	NOUN
admet-159	6	35	was	be	AUX
admet-159	6	36	used	use	VERB
admet-159	6	37	to	to	PART
admet-159	6	38	investigate	investigate	VERB
admet-159	6	39	a	a	DET
admet-159	6	40	-	-	PUNCT
admet-159	6	41	syn	syn	NOUN
admet-159	6	42	aggregation	aggregation	NOUN
admet-159	6	43	after	after	ADP
admet-159	6	44	incubating	incubate	VERB
admet-159	6	45	with	with	ADP
admet-159	6	46	mn	mn	PROPN
admet-159	6	47	and/or	and/or	CCONJ
admet-159	6	48	cu	cu	PROPN
admet-159	6	49	in	in	ADP
admet-159	6	50	vitro	vitro	X
admet-159	6	51	.	.	PUNCT
admet-159	7	1	a	a	DET
admet-159	7	2	two	two	NUM
admet-159	7	3	-	-	PUNCT
admet-159	7	4	chamber	chamber	NOUN
admet-159	7	5	transwell	transwell	NOUN
admet-159	7	6	system	system	NOUN
admet-159	7	7	was	be	AUX
admet-159	7	8	used	use	VERB
admet-159	7	9	to	to	PART
admet-159	7	10	study	study	VERB
admet-159	7	11	a	a	DET
admet-159	7	12	-	-	PUNCT
admet-159	7	13	syn	syn	NOUN
admet-159	7	14	transport	transport	NOUN
admet-159	7	15	by	by	ADP
admet-159	7	16	bcsfb	bcsfb	PROPN
admet-159	7	17	monolayer.data	monolayer.data	PROPN
admet-159	7	18	revealed	reveal	VERB
admet-159	7	19	the	the	DET
admet-159	7	20	expression	expression	NOUN
admet-159	7	21	of	of	ADP
admet-159	7	22	endogenous	endogenous	ADJ
admet-159	7	23	a	a	PRON
admet-159	7	24	-	-	PUNCT
admet-159	7	25	syn	syn	NOUN
admet-159	7	26	in	in	ADP
admet-159	7	27	rat	rat	NOUN
admet-159	7	28	choroid	choroid	NOUN
admet-159	7	29	plexus	plexus	NOUN
admet-159	7	30	tissue	tissue	NOUN
admet-159	7	31	and	and	CCONJ
admet-159	7	32	immortalized	immortalize	VERB
admet-159	7	33	choroidal	choroidal	ADJ
admet-159	7	34	epithelial	epithelial	ADJ
admet-159	7	35	z310	z310	PROPN
admet-159	7	36	cells	cell	NOUN
admet-159	7	37	.	.	PUNCT
admet-159	8	1	the	the	DET
admet-159	8	2	cultured	cultured	ADJ
admet-159	8	3	primary	primary	ADJ
admet-159	8	4	choroidal	choroidal	NOUN
admet-159	8	5	epithelia	epithelia	NOUN
admet-159	8	6	from	from	ADP
admet-159	8	7	rats	rat	NOUN
admet-159	8	8	showed	show	VERB
admet-159	8	9	the	the	DET
admet-159	8	10	ability	ability	NOUN
admet-159	8	11	to	to	PART
admet-159	8	12	take	take	VERB
admet-159	8	13	up	up	ADP
admet-159	8	14	a	a	DET
admet-159	8	15	-	-	PUNCT
admet-159	8	16	syn	syn	NOUN
admet-159	8	17	from	from	ADP
admet-159	8	18	extracellular	extracellular	ADJ
admet-159	8	19	medium	medium	NOUN
admet-159	8	20	and	and	CCONJ
admet-159	8	21	transport	transport	NOUN
admet-159	8	22	a	a	NOUN
admet-159	8	23	-	-	PUNCT
admet-159	8	24	syn	syn	NOUN
admet-159	8	25	across	across	ADP
admet-159	8	26	the	the	DET
admet-159	8	27	cellular	cellular	ADJ
admet-159	8	28	monolayer	monolayer	NOUN
admet-159	8	29	from	from	ADP
admet-159	8	30	the	the	DET
admet-159	8	31	donor	donor	NOUN
admet-159	8	32	to	to	ADP
admet-159	8	33	receiver	receiver	ADJ
admet-159	8	34	chamber	chamber	NOUN
admet-159	8	35	.	.	PUNCT
admet-159	9	1	exposure	exposure	NOUN
admet-159	9	2	of	of	ADP
admet-159	9	3	cells	cell	NOUN
admet-159	9	4	with	with	ADP
admet-159	9	5	mn	mn	PROPN
admet-159	9	6	induced	induce	VERB
admet-159	9	7	intracellular	intracellular	ADJ
admet-159	9	8	a	a	PRON
admet-159	9	9	-	-	PUNCT
admet-159	9	10	syn	syn	NOUN
admet-159	9	11	accumulation	accumulation	NOUN
admet-159	9	12	without	without	ADP
admet-159	9	13	causing	cause	VERB
admet-159	9	14	any	any	DET
admet-159	9	15	significant	significant	ADJ
admet-159	9	16	changes	change	NOUN
admet-159	9	17	in	in	ADP
admet-159	9	18	a	a	DET
admet-159	9	19	-	-	PUNCT
admet-159	9	20	syn	syn	NOUN
admet-159	9	21	mrna	mrna	PROPN
admet-159	9	22	expression	expression	NOUN
admet-159	9	23	.	.	PUNCT
admet-159	10	1	a	a	DET
admet-159	10	2	significant	significant	ADJ
admet-159	10	3	increase	increase	NOUN
admet-159	10	4	in	in	ADP
admet-159	10	5	a	a	DET
admet-159	10	6	-	-	PUNCT
admet-159	10	7	syn	syn	NOUN
admet-159	10	8	aggregation	aggregation	NOUN
admet-159	10	9	in	in	ADP
admet-159	10	10	a	a	DET
admet-159	10	11	cell	cell	NOUN
admet-159	10	12	-	-	PUNCT
admet-159	10	13	free	free	ADJ
admet-159	10	14	system	system	NOUN
admet-159	10	15	was	be	AUX
admet-159	10	16	observed	observe	VERB
admet-159	10	17	with	with	ADP
admet-159	10	18	the	the	DET
admet-159	10	19	presence	presence	NOUN
admet-159	10	20	of	of	ADP
admet-159	10	21	mn	mn	PROPN
admet-159	10	22	.	.	PUNCT
admet-159	11	1	moreover	moreover	ADV
admet-159	11	2	,	,	PUNCT
admet-159	11	3	mn	mn	PROPN
admet-159	11	4	exposure	exposure	NOUN
admet-159	11	5	resulted	result	VERB
admet-159	11	6	in	in	ADP
admet-159	11	7	a	a	DET
admet-159	11	8	significant	significant	ADJ
admet-159	11	9	uptake	uptake	NOUN
admet-159	11	10	of	of	ADP
admet-159	11	11	a	a	DET
admet-159	11	12	-	-	PUNCT
admet-159	11	13	syn	syn	NOUN
admet-159	11	14	by	by	ADP
admet-159	11	15	primary	primary	ADJ
admet-159	11	16	cells.these	cells.these	ADJ
admet-159	11	17	data	datum	NOUN
admet-159	11	18	indicate	indicate	VERB
admet-159	11	19	that	that	SCONJ
admet-159	11	20	the	the	DET
admet-159	11	21	bcsfb	bcsfb	NOUN
admet-159	11	22	expresses	express	VERB
admet-159	11	23	a	a	DET
admet-159	11	24	-	-	PUNCT
admet-159	11	25	syn	syn	NOUN
admet-159	11	26	endogenously	endogenously	ADV
admet-159	11	27	and	and	CCONJ
admet-159	11	28	is	be	AUX
admet-159	11	29	capable	capable	ADJ
admet-159	11	30	of	of	ADP
admet-159	11	31	transporting	transport	VERB
admet-159	11	32	a	a	DET
admet-159	11	33	-	-	PUNCT
admet-159	11	34	syn	syn	NOUN
admet-159	11	35	across	across	ADP
admet-159	11	36	the	the	DET
admet-159	11	37	bcsfb	bcsfb	PROPN
admet-159	11	38	monolayer	monolayer	NOUN
admet-159	11	39	;	;	PUNCT
admet-159	11	40	mn	mn	PROPN
admet-159	11	41	exposure	exposure	NOUN
admet-159	11	42	apparently	apparently	ADV
admet-159	11	43	increases	increase	VERB
admet-159	11	44	a	a	DET
admet-159	11	45	-	-	PUNCT
admet-159	11	46	syn	syn	NOUN
admet-159	11	47	accumulation	accumulation	NOUN
admet-159	11	48	in	in	ADP
admet-159	11	49	the	the	DET
admet-159	11	50	bcsfb	bcsfb	NOUN
admet-159	11	51	by	by	ADP
admet-159	11	52	facilitating	facilitate	VERB
admet-159	11	53	its	its	PRON
admet-159	11	54	uptake	uptake	NOUN
admet-159	11	55	and	and	CCONJ
admet-159	11	56	intracellular	intracellular	ADJ
admet-159	11	57	aggregation	aggregation	NOUN
admet-159	11	58	.	.	PUNCT
admet-159	12	1	keywords	keyword	VERB
admet-159	12	2	a	a	DET
admet-159	12	3	-	-	PUNCT
admet-159	12	4	synuclein	synuclein	NOUN
admet-159	12	5	transport	transport	NOUN
admet-159	12	6	;	;	PUNCT
admet-159	12	7	cerebrospinal	cerebrospinal	ADJ
admet-159	12	8	fluid	fluid	NOUN
admet-159	12	9	;	;	PUNCT
admet-159	12	10	blood	blood	NOUN
admet-159	12	11	-	-	PUNCT
admet-159	12	12	cerebrospinal	cerebrospinal	ADJ
admet-159	12	13	fluid	fluid	NOUN
admet-159	12	14	barrier	barrier	NOUN
admet-159	12	15	;	;	PUNCT
admet-159	12	16	manganese	manganese	ADJ
admet-159	12	17	exposure	exposure	NOUN
admet-159	12	18	introduction	introduction	NOUN
admet-159	12	19	parkinson	parkinson	NOUN
admet-159	12	20	’s	’s	PART
admet-159	12	21	disease	disease	NOUN
admet-159	12	22	(	(	PUNCT
admet-159	12	23	pd	pd	NOUN
admet-159	12	24	)	)	PUNCT
admet-159	12	25	is	be	AUX
admet-159	12	26	the	the	DET
admet-159	12	27	second	second	ADJ
admet-159	12	28	most	most	ADV
admet-159	12	29	common	common	ADJ
admet-159	12	30	neurodegenerative	neurodegenerative	ADJ
admet-159	12	31	disorder	disorder	NOUN
admet-159	12	32	behind	behind	ADP
admet-159	12	33	alzheimer	alzheimer	PROPN
admet-159	12	34	’s	’s	PART
admet-159	12	35	disease	disease	NOUN
admet-159	12	36	and	and	CCONJ
admet-159	12	37	is	be	AUX
admet-159	12	38	characterized	characterize	VERB
admet-159	12	39	by	by	ADP
admet-159	12	40	dopaminergic	dopaminergic	ADJ
admet-159	12	41	neurodegeneration	neurodegeneration	NOUN
admet-159	12	42	in	in	ADP
admet-159	12	43	the	the	DET
admet-159	12	44	substantia	substantia	NOUN
admet-159	12	45	nigra	nigra	NOUN
admet-159	12	46	with	with	ADP
admet-159	12	47	the	the	DET
admet-159	12	48	following	follow	VERB
admet-159	12	49	hallmark	hallmark	ADJ
admet-159	12	50	symptoms	symptom	NOUN
admet-159	12	51	:	:	PUNCT
admet-159	12	52	bradykinesia	bradykinesia	NOUN
admet-159	12	53	,	,	PUNCT
admet-159	12	54	rigidity	rigidity	NOUN
admet-159	12	55	,	,	PUNCT
admet-159	12	56	postural	postural	ADJ
admet-159	12	57	instability	instability	NOUN
admet-159	12	58	,	,	PUNCT
admet-159	12	59	and	and	CCONJ
admet-159	12	60	resting	rest	VERB
admet-159	12	61	tremors	tremor	NOUN
admet-159	13	1	[	[	X
admet-159	13	2	1	1	NUM
admet-159	13	3	]	]	PUNCT
admet-159	13	4	.	.	PUNCT
admet-159	14	1	dysfunction	dysfunction	NOUN
admet-159	14	2	and	and	CCONJ
admet-159	14	3	aggregation	aggregation	NOUN
admet-159	14	4	of	of	ADP
admet-159	14	5	the	the	DET
admet-159	14	6	protein	protein	NOUN
admet-159	14	7	,	,	PUNCT
admet-159	14	8	-synuclein	-synuclein	PROPN
admet-159	14	9	(	(	PUNCT
admet-159	14	10	a	a	DET
admet-159	14	11	-	-	PUNCT
admet-159	14	12	syn	syn	NOUN
admet-159	14	13	)	)	PUNCT
admet-159	14	14	has	have	AUX
admet-159	14	15	been	be	AUX
admet-159	14	16	associated	associate	VERB
admet-159	14	17	with	with	ADP
admet-159	14	18	pd	pd	PROPN
admet-159	14	19	pathophysiology	pathophysiology	NOUN
admet-159	14	20	[	[	X
admet-159	14	21	2	2	NUM
admet-159	14	22	]	]	PUNCT
admet-159	14	23	.	.	PUNCT
admet-159	15	1	the	the	DET
admet-159	15	2	protein	protein	NOUN
admet-159	15	3	a	a	NOUN
admet-159	15	4	-	-	PUNCT
admet-159	15	5	syn	syn	NOUN
admet-159	15	6	is	be	AUX
admet-159	15	7	small	small	ADJ
admet-159	15	8	(	(	PUNCT
admet-159	15	9	14.5	14.5	NUM
admet-159	15	10	kda	kda	NOUN
admet-159	15	11	)	)	PUNCT
admet-159	15	12	,	,	PUNCT
admet-159	15	13	natively	natively	ADV
admet-159	15	14	unfolded	unfold	VERB
admet-159	15	15	,	,	PUNCT
admet-159	15	16	and	and	CCONJ
admet-159	15	17	expressed	express	VERB
admet-159	15	18	in	in	ADP
admet-159	15	19	a	a	DET
admet-159	15	20	wide	wide	ADJ
admet-159	15	21	range	range	NOUN
admet-159	15	22	of	of	ADP
admet-159	15	23	cell	cell	NOUN
admet-159	15	24	types	type	NOUN
admet-159	15	25	.	.	PUNCT
admet-159	16	1	the	the	DET
admet-159	16	2	exact	exact	ADJ
admet-159	16	3	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-159	16	4	mailto:wzheng@purdue.edu	mailto:wzheng@purdue.edu	PROPN
admet-159	16	5	bates	bates	PROPN
admet-159	16	6	et	et	PROPN
admet-159	16	7	al	al	PROPN
admet-159	16	8	.	.	PROPN
admet-159	16	9	admet	admet	PROPN
admet-159	16	10	&	&	CCONJ
admet-159	16	11	dmpk	dmpk	PROPN
admet-159	16	12	3(1	3(1	NUM
admet-159	16	13	)	)	PUNCT
admet-159	16	14	(	(	PUNCT
admet-159	16	15	2015	2015	NUM
admet-159	16	16	)	)	PUNCT
admet-159	16	17	15	15	NUM
admet-159	16	18	-	-	SYM
admet-159	16	19	33	33	NUM
admet-159	16	20	16	16	NUM
admet-159	16	21	function	function	NOUN
admet-159	16	22	of	of	ADP
admet-159	16	23	wild	wild	ADJ
admet-159	16	24	-	-	PUNCT
admet-159	16	25	type	type	NOUN
admet-159	16	26	a	a	NOUN
admet-159	16	27	-	-	PUNCT
admet-159	16	28	syn	syn	NOUN
admet-159	16	29	is	be	AUX
admet-159	16	30	uncertain	uncertain	ADJ
admet-159	16	31	.	.	PUNCT
admet-159	17	1	some	some	DET
admet-159	17	2	researchers	researcher	NOUN
admet-159	17	3	have	have	AUX
admet-159	17	4	suggested	suggest	VERB
admet-159	17	5	potential	potential	ADJ
admet-159	17	6	functions	function	NOUN
admet-159	17	7	of	of	ADP
admet-159	17	8	a	a	DET
admet-159	17	9	-	-	PUNCT
admet-159	17	10	syn	syn	NOUN
admet-159	17	11	in	in	ADP
admet-159	17	12	synaptic	synaptic	ADJ
admet-159	17	13	plasticity	plasticity	NOUN
admet-159	17	14	[	[	X
admet-159	17	15	3	3	NUM
admet-159	17	16	]	]	PUNCT
admet-159	17	17	,	,	PUNCT
admet-159	17	18	synaptic	synaptic	ADJ
admet-159	17	19	pool	pool	NOUN
admet-159	17	20	maintenance	maintenance	NOUN
admet-159	17	21	[	[	X
admet-159	17	22	4	4	NUM
admet-159	17	23	]	]	PUNCT
admet-159	17	24	,	,	PUNCT
admet-159	17	25	regulation	regulation	NOUN
admet-159	17	26	of	of	ADP
admet-159	17	27	dopamine	dopamine	NOUN
admet-159	17	28	synthesis	synthesis	NOUN
admet-159	17	29	[	[	X
admet-159	17	30	5	5	NUM
admet-159	17	31	]	]	PUNCT
admet-159	17	32	,	,	PUNCT
admet-159	17	33	and	and	CCONJ
admet-159	17	34	vesicular	vesicular	ADJ
admet-159	17	35	dynamics	dynamic	NOUN
admet-159	17	36	,	,	PUNCT
admet-159	17	37	e.g.	e.g.	ADV
admet-159	17	38	stabilization	stabilization	NOUN
admet-159	17	39	and	and	CCONJ
admet-159	17	40	exocytic	exocytic	ADJ
admet-159	17	41	fusion	fusion	NOUN
admet-159	17	42	at	at	ADP
admet-159	17	43	the	the	DET
admet-159	17	44	presynapse	presynapse	NOUN
admet-159	17	45	[	[	X
admet-159	17	46	2,6,7	2,6,7	NUM
admet-159	17	47	]	]	PUNCT
admet-159	17	48	.	.	PUNCT
admet-159	18	1	the	the	DET
admet-159	18	2	aggregation	aggregation	NOUN
admet-159	18	3	of	of	ADP
admet-159	18	4	a	a	DET
admet-159	18	5	-	-	PUNCT
admet-159	18	6	syn	syn	NOUN
admet-159	18	7	within	within	ADP
admet-159	18	8	neurons	neuron	NOUN
admet-159	18	9	results	result	NOUN
admet-159	18	10	in	in	ADP
admet-159	18	11	the	the	DET
admet-159	18	12	efflux	efflux	NOUN
admet-159	18	13	of	of	ADP
admet-159	18	14	aggregate	aggregate	ADJ
admet-159	18	15	species	specie	NOUN
admet-159	18	16	from	from	ADP
admet-159	18	17	the	the	DET
admet-159	18	18	cell	cell	NOUN
admet-159	18	19	to	to	ADP
admet-159	18	20	the	the	DET
admet-159	18	21	interstitial	interstitial	ADJ
admet-159	18	22	fluid	fluid	NOUN
admet-159	18	23	(	(	PUNCT
admet-159	18	24	isf	isf	NOUN
admet-159	18	25	)	)	PUNCT
admet-159	19	1	[	[	X
admet-159	19	2	8,9	8,9	NUM
admet-159	19	3	]	]	PUNCT
admet-159	19	4	,	,	PUNCT
admet-159	19	5	which	which	PRON
admet-159	19	6	merges	merge	VERB
admet-159	19	7	with	with	ADP
admet-159	19	8	the	the	DET
admet-159	19	9	cerebrospinal	cerebrospinal	ADJ
admet-159	19	10	fluid	fluid	NOUN
admet-159	19	11	(	(	PUNCT
admet-159	19	12	csf	csf	NOUN
admet-159	19	13	)	)	PUNCT
admet-159	19	14	.	.	PUNCT
admet-159	20	1	the	the	DET
admet-159	20	2	csf	csf	NOUN
admet-159	20	3	is	be	AUX
admet-159	20	4	mainly	mainly	ADV
admet-159	20	5	produced	produce	VERB
admet-159	20	6	by	by	ADP
admet-159	20	7	the	the	DET
admet-159	20	8	choroid	choroid	NOUN
admet-159	20	9	plexus	plexus	NOUN
admet-159	20	10	located	locate	VERB
admet-159	20	11	in	in	ADP
admet-159	20	12	brain	brain	NOUN
admet-159	20	13	ventricles	ventricle	NOUN
admet-159	20	14	.	.	PUNCT
admet-159	21	1	the	the	DET
admet-159	21	2	choroid	choroid	NOUN
admet-159	21	3	plexus	plexus	NOUN
admet-159	21	4	forms	form	VERB
admet-159	21	5	the	the	DET
admet-159	21	6	blood	blood	NOUN
admet-159	21	7	-	-	PUNCT
admet-159	21	8	csf	csf	ADJ
admet-159	21	9	barrier	barrier	NOUN
admet-159	21	10	(	(	PUNCT
admet-159	21	11	bcsfb	bcsfb	PROPN
admet-159	21	12	)	)	PUNCT
admet-159	21	13	,	,	PUNCT
admet-159	21	14	which	which	PRON
admet-159	21	15	separates	separate	VERB
admet-159	21	16	the	the	DET
admet-159	21	17	blood	blood	NOUN
admet-159	21	18	circulation	circulation	NOUN
admet-159	21	19	from	from	ADP
admet-159	21	20	the	the	DET
admet-159	21	21	csf	csf	PROPN
admet-159	21	22	.	.	PROPN
admet-159	22	1	for	for	ADP
admet-159	22	2	its	its	PRON
admet-159	22	3	continuous	continuous	ADJ
admet-159	22	4	cycle	cycle	NOUN
admet-159	22	5	throughout	throughout	ADP
admet-159	22	6	brain	brain	NOUN
admet-159	22	7	structure	structure	NOUN
admet-159	22	8	,	,	PUNCT
admet-159	22	9	the	the	DET
admet-159	22	10	csf	csf	ADJ
admet-159	22	11	functions	function	NOUN
admet-159	22	12	as	as	ADP
admet-159	22	13	a	a	DET
admet-159	22	14	“	"	PUNCT
admet-159	22	15	sink	sink	NOUN
admet-159	22	16	”	"	PUNCT
admet-159	22	17	,	,	PUNCT
admet-159	22	18	where	where	SCONJ
admet-159	22	19	waste	waste	NOUN
admet-159	22	20	products	product	NOUN
admet-159	22	21	can	can	AUX
admet-159	22	22	be	be	AUX
admet-159	22	23	collected	collect	VERB
admet-159	22	24	from	from	ADP
admet-159	22	25	the	the	DET
admet-159	22	26	isf	isf	PROPN
admet-159	22	27	and	and	CCONJ
admet-159	22	28	removed	remove	VERB
admet-159	22	29	from	from	ADP
admet-159	22	30	the	the	DET
admet-159	22	31	brain	brain	NOUN
admet-159	22	32	via	via	ADP
admet-159	22	33	the	the	DET
admet-159	22	34	bcsfb	bcsfb	NOUN
admet-159	22	35	or	or	CCONJ
admet-159	22	36	subarachnoid	subarachnoid	VERB
admet-159	22	37	drainage	drainage	NOUN
admet-159	22	38	[	[	X
admet-159	22	39	10,11	10,11	NOUN
admet-159	22	40	]	]	PUNCT
admet-159	22	41	.	.	PUNCT
admet-159	23	1	the	the	DET
admet-159	23	2	a	a	PROPN
admet-159	23	3	-	-	PUNCT
admet-159	23	4	syn	syn	NOUN
admet-159	23	5	molecules	molecule	NOUN
admet-159	23	6	present	present	ADJ
admet-159	23	7	in	in	ADP
admet-159	23	8	the	the	DET
admet-159	23	9	csf	csf	NOUN
admet-159	23	10	are	be	AUX
admet-159	23	11	believed	believe	VERB
admet-159	23	12	to	to	PART
admet-159	23	13	originate	originate	VERB
admet-159	23	14	primarily	primarily	ADV
admet-159	23	15	from	from	ADP
admet-159	23	16	neurons	neuron	NOUN
admet-159	23	17	and	and	CCONJ
admet-159	23	18	neuroglia	neuroglia	NOUN
admet-159	24	1	[	[	X
admet-159	24	2	12	12	NUM
admet-159	24	3	]	]	PUNCT
admet-159	24	4	,	,	PUNCT
admet-159	24	5	and	and	CCONJ
admet-159	24	6	the	the	DET
admet-159	24	7	a	a	PROPN
admet-159	24	8	-	-	PUNCT
admet-159	24	9	syn	syn	NOUN
admet-159	24	10	concentration	concentration	NOUN
admet-159	24	11	in	in	ADP
admet-159	24	12	the	the	DET
admet-159	24	13	csf	csf	NOUN
admet-159	24	14	has	have	AUX
admet-159	24	15	been	be	AUX
admet-159	24	16	compared	compare	VERB
admet-159	24	17	against	against	ADP
admet-159	24	18	a	a	DET
admet-159	24	19	-	-	PUNCT
admet-159	24	20	syn	syn	NOUN
admet-159	24	21	in	in	ADP
admet-159	24	22	blood	blood	NOUN
admet-159	24	23	as	as	ADP
admet-159	24	24	potential	potential	ADJ
admet-159	24	25	biomarkers	biomarker	NOUN
admet-159	24	26	for	for	ADP
admet-159	24	27	pd	pd	PROPN
admet-159	24	28	progression	progression	NOUN
admet-159	24	29	[	[	X
admet-159	24	30	13	13	NUM
admet-159	24	31	-	-	SYM
admet-159	24	32	15	15	NUM
admet-159	24	33	]	]	PUNCT
admet-159	24	34	.	.	PUNCT
admet-159	25	1	literature	literature	NOUN
admet-159	25	2	evidence	evidence	NOUN
admet-159	25	3	suggests	suggest	VERB
admet-159	25	4	that	that	SCONJ
admet-159	25	5	the	the	DET
admet-159	25	6	transport	transport	NOUN
admet-159	25	7	of	of	ADP
admet-159	25	8	a	a	DET
admet-159	25	9	-	-	PUNCT
admet-159	25	10	syn	syn	NOUN
admet-159	25	11	aggregates	aggregate	NOUN
admet-159	25	12	between	between	ADP
admet-159	25	13	neurons	neuron	NOUN
admet-159	25	14	and	and	CCONJ
admet-159	25	15	astrocytes	astrocyte	NOUN
admet-159	25	16	of	of	ADP
admet-159	25	17	the	the	DET
admet-159	25	18	blood	blood	NOUN
admet-159	25	19	-	-	PUNCT
admet-159	25	20	brain	brain	NOUN
admet-159	25	21	barrier	barrier	NOUN
admet-159	25	22	(	(	PUNCT
admet-159	25	23	bbb	bbb	NOUN
admet-159	25	24	)	)	PUNCT
admet-159	25	25	is	be	AUX
admet-159	25	26	by	by	ADP
admet-159	25	27	endocytosis	endocytosis	NOUN
admet-159	25	28	and	and	CCONJ
admet-159	25	29	exocytosis	exocytosis	NOUN
admet-159	25	30	[	[	X
admet-159	25	31	8,9,16,17	8,9,16,17	NOUN
admet-159	25	32	]	]	PUNCT
admet-159	25	33	.	.	PUNCT
admet-159	26	1	since	since	SCONJ
admet-159	26	2	the	the	DET
admet-159	26	3	a	a	PROPN
admet-159	26	4	-	-	PUNCT
admet-159	26	5	syn	syn	NOUN
admet-159	26	6	level	level	NOUN
admet-159	26	7	in	in	ADP
admet-159	26	8	the	the	DET
admet-159	26	9	blood	blood	NOUN
admet-159	26	10	is	be	AUX
admet-159	26	11	over	over	ADP
admet-159	26	12	1000	1000	NUM
admet-159	26	13	-	-	NUM
admet-159	26	14	fold	fold	VERB
admet-159	26	15	higher	high	ADJ
admet-159	26	16	than	than	ADP
admet-159	26	17	that	that	PRON
admet-159	26	18	in	in	ADP
admet-159	26	19	the	the	DET
admet-159	26	20	csf	csf	NOUN
admet-159	26	21	in	in	ADP
admet-159	26	22	healthy	healthy	ADJ
admet-159	26	23	humans	human	NOUN
admet-159	26	24	[	[	X
admet-159	26	25	12,14,18	12,14,18	NUM
admet-159	26	26	]	]	X
admet-159	26	27	,	,	PUNCT
admet-159	26	28	any	any	DET
admet-159	26	29	possible	possible	ADJ
admet-159	26	30	transport	transport	NOUN
admet-159	26	31	of	of	ADP
admet-159	26	32	a	a	DET
admet-159	26	33	-	-	PUNCT
admet-159	26	34	syn	syn	NOUN
admet-159	26	35	from	from	ADP
admet-159	26	36	the	the	DET
admet-159	26	37	csf	csf	NOUN
admet-159	26	38	back	back	ADV
admet-159	26	39	to	to	ADP
admet-159	26	40	the	the	DET
admet-159	26	41	blood	blood	NOUN
admet-159	26	42	must	must	AUX
admet-159	26	43	be	be	AUX
admet-159	26	44	energy	energy	NOUN
admet-159	26	45	dependent	dependent	ADJ
admet-159	26	46	and	and	CCONJ
admet-159	26	47	against	against	ADP
admet-159	26	48	this	this	DET
admet-159	26	49	large	large	ADJ
admet-159	26	50	concentration	concentration	NOUN
admet-159	26	51	gradient	gradient	NOUN
admet-159	26	52	.	.	PUNCT
admet-159	27	1	these	these	DET
admet-159	27	2	transport	transport	NOUN
admet-159	27	3	properties	property	NOUN
admet-159	27	4	,	,	PUNCT
admet-159	27	5	however	however	ADV
admet-159	27	6	,	,	PUNCT
admet-159	27	7	have	have	VERB
admet-159	27	8	yet	yet	ADV
admet-159	27	9	to	to	PART
admet-159	27	10	be	be	AUX
admet-159	27	11	thoroughly	thoroughly	ADV
admet-159	27	12	investigated	investigate	VERB
admet-159	27	13	at	at	ADP
admet-159	27	14	the	the	DET
admet-159	27	15	bcsfb	bcsfb	NOUN
admet-159	27	16	or	or	CCONJ
admet-159	27	17	bbb	bbb	PROPN
admet-159	27	18	.	.	PUNCT
admet-159	28	1	for	for	ADP
admet-159	28	2	detailed	detailed	ADJ
admet-159	28	3	discussions	discussion	NOUN
admet-159	28	4	,	,	PUNCT
admet-159	28	5	please	please	INTJ
admet-159	28	6	see	see	VERB
admet-159	28	7	a	a	DET
admet-159	28	8	recent	recent	ADJ
admet-159	28	9	review	review	NOUN
admet-159	28	10	by	by	ADP
admet-159	28	11	bates	bate	NOUN
admet-159	28	12	and	and	CCONJ
admet-159	28	13	zheng	zheng	PROPN
admet-159	29	1	[	[	X
admet-159	29	2	19	19	NUM
admet-159	29	3	]	]	PUNCT
admet-159	29	4	.	.	PUNCT
admet-159	30	1	manganese	manganese	NOUN
admet-159	30	2	(	(	PUNCT
admet-159	30	3	mn	mn	PROPN
admet-159	30	4	)	)	PUNCT
admet-159	30	5	is	be	AUX
admet-159	30	6	an	an	DET
admet-159	30	7	essential	essential	ADJ
admet-159	30	8	trace	trace	NOUN
admet-159	30	9	element	element	NOUN
admet-159	30	10	utilized	utilize	VERB
admet-159	30	11	for	for	ADP
admet-159	30	12	a	a	DET
admet-159	30	13	variety	variety	NOUN
admet-159	30	14	of	of	ADP
admet-159	30	15	functions	function	NOUN
admet-159	30	16	in	in	ADP
admet-159	30	17	the	the	DET
admet-159	30	18	brain	brain	NOUN
admet-159	30	19	including	include	VERB
admet-159	30	20	glutamate	glutamate	NOUN
admet-159	30	21	and	and	CCONJ
admet-159	30	22	gaba	gaba	NOUN
admet-159	30	23	metabolism	metabolism	NOUN
admet-159	30	24	,	,	PUNCT
admet-159	30	25	astrocyte	astrocyte	NOUN
admet-159	30	26	morphology	morphology	NOUN
admet-159	30	27	and	and	CCONJ
admet-159	30	28	migration	migration	NOUN
admet-159	30	29	,	,	PUNCT
admet-159	30	30	and	and	CCONJ
admet-159	30	31	the	the	DET
admet-159	30	32	neutralization	neutralization	NOUN
admet-159	30	33	of	of	ADP
admet-159	30	34	reactive	reactive	ADJ
admet-159	30	35	oxidative	oxidative	ADJ
admet-159	30	36	species	specie	NOUN
admet-159	30	37	[	[	X
admet-159	30	38	20	20	NUM
admet-159	30	39	]	]	PUNCT
admet-159	30	40	.	.	PUNCT
admet-159	31	1	mn	mn	PROPN
admet-159	31	2	overexposure	overexposure	NOUN
admet-159	31	3	occurs	occur	VERB
admet-159	31	4	primarily	primarily	ADV
admet-159	31	5	in	in	ADP
admet-159	31	6	the	the	DET
admet-159	31	7	occupational	occupational	ADJ
admet-159	31	8	setting	setting	NOUN
admet-159	31	9	for	for	ADP
admet-159	31	10	welders	welder	NOUN
admet-159	31	11	,	,	PUNCT
admet-159	31	12	smelters	smelter	NOUN
admet-159	31	13	,	,	PUNCT
admet-159	31	14	and	and	CCONJ
admet-159	31	15	others	other	NOUN
admet-159	31	16	with	with	ADP
admet-159	31	17	related	related	ADJ
admet-159	31	18	professions	profession	NOUN
admet-159	31	19	[	[	X
admet-159	31	20	21,22	21,22	X
admet-159	31	21	]	]	X
admet-159	31	22	,	,	PUNCT
admet-159	31	23	but	but	CCONJ
admet-159	31	24	it	it	PRON
admet-159	31	25	also	also	ADV
admet-159	31	26	occurs	occur	VERB
admet-159	31	27	in	in	ADP
admet-159	31	28	premature	premature	ADJ
admet-159	31	29	newborns	newborn	NOUN
admet-159	31	30	via	via	ADP
admet-159	31	31	medically	medically	ADV
admet-159	31	32	administered	administer	VERB
admet-159	31	33	paternal	paternal	ADJ
admet-159	31	34	nutrition	nutrition	NOUN
admet-159	31	35	[	[	X
admet-159	31	36	20	20	NUM
admet-159	31	37	]	]	PUNCT
admet-159	31	38	.	.	PUNCT
admet-159	32	1	excess	excess	PROPN
admet-159	32	2	mn	mn	PROPN
admet-159	32	3	has	have	AUX
admet-159	32	4	been	be	AUX
admet-159	32	5	shown	show	VERB
admet-159	32	6	to	to	PART
admet-159	32	7	accumulate	accumulate	VERB
admet-159	32	8	primarily	primarily	ADV
admet-159	32	9	in	in	ADP
admet-159	32	10	the	the	DET
admet-159	32	11	globus	globus	NOUN
admet-159	32	12	pallidus	pallidus	NOUN
admet-159	32	13	;	;	PUNCT
admet-159	32	14	more	more	ADV
admet-159	32	15	recent	recent	ADJ
admet-159	32	16	data	datum	NOUN
admet-159	32	17	have	have	AUX
admet-159	32	18	shown	show	VERB
admet-159	32	19	that	that	SCONJ
admet-159	32	20	mn	mn	PROPN
admet-159	32	21	also	also	ADV
admet-159	32	22	accumulates	accumulate	VERB
admet-159	32	23	in	in	ADP
admet-159	32	24	the	the	DET
admet-159	32	25	substantia	substantia	NOUN
admet-159	32	26	nigra	nigra	NOUN
admet-159	33	1	[	[	X
admet-159	33	2	23	23	NUM
admet-159	33	3	-	-	SYM
admet-159	33	4	25	25	NUM
admet-159	33	5	]	]	PUNCT
admet-159	33	6	.	.	PUNCT
admet-159	34	1	in	in	ADP
admet-159	34	2	humans	human	NOUN
admet-159	34	3	and	and	CCONJ
admet-159	34	4	rats	rat	NOUN
admet-159	34	5	,	,	PUNCT
admet-159	34	6	excess	excess	ADJ
admet-159	34	7	mn	mn	PROPN
admet-159	34	8	has	have	AUX
admet-159	34	9	been	be	AUX
admet-159	34	10	associated	associate	VERB
admet-159	34	11	with	with	ADP
admet-159	34	12	increased	increase	VERB
admet-159	34	13	gaba	gaba	NOUN
admet-159	34	14	levels	level	NOUN
admet-159	34	15	at	at	ADP
admet-159	34	16	the	the	DET
admet-159	34	17	basal	basal	ADJ
admet-159	34	18	ganglia	ganglia	NOUN
admet-159	34	19	,	,	PUNCT
admet-159	34	20	impaired	impaired	ADJ
admet-159	34	21	iron	iron	NOUN
admet-159	34	22	and	and	CCONJ
admet-159	34	23	copper	copper	NOUN
admet-159	34	24	homeostasis	homeostasis	NOUN
admet-159	34	25	,	,	PUNCT
admet-159	34	26	and	and	CCONJ
admet-159	34	27	mitochondrial	mitochondrial	ADJ
admet-159	34	28	dysfunction	dysfunction	NOUN
admet-159	35	1	[	[	X
admet-159	35	2	26	26	NUM
admet-159	35	3	-	-	SYM
admet-159	35	4	30	30	NUM
admet-159	35	5	]	]	PUNCT
admet-159	35	6	.	.	PUNCT
admet-159	36	1	individuals	individual	NOUN
admet-159	36	2	suffering	suffer	VERB
admet-159	36	3	from	from	ADP
admet-159	36	4	mn	mn	PROPN
admet-159	36	5	intoxication	intoxication	NOUN
admet-159	36	6	display	display	NOUN
admet-159	36	7	clinical	clinical	ADJ
admet-159	36	8	symptoms	symptom	NOUN
admet-159	36	9	including	include	VERB
admet-159	36	10	impaired	impaired	ADJ
admet-159	36	11	balance	balance	NOUN
admet-159	36	12	and	and	CCONJ
admet-159	36	13	gait	gait	NOUN
admet-159	36	14	,	,	PUNCT
admet-159	36	15	kinetic	kinetic	ADJ
admet-159	36	16	tremors	tremor	NOUN
admet-159	36	17	,	,	PUNCT
admet-159	36	18	dystonia	dystonia	NOUN
admet-159	36	19	,	,	PUNCT
admet-159	36	20	cognitive	cognitive	ADJ
admet-159	36	21	problems	problem	NOUN
admet-159	36	22	,	,	PUNCT
admet-159	36	23	memory	memory	NOUN
admet-159	36	24	loss	loss	NOUN
admet-159	36	25	,	,	PUNCT
admet-159	36	26	anxiety	anxiety	NOUN
admet-159	36	27	,	,	PUNCT
admet-159	36	28	and	and	CCONJ
admet-159	36	29	aggression	aggression	NOUN
admet-159	36	30	[	[	X
admet-159	36	31	31,32	31,32	NUM
admet-159	36	32	]	]	PUNCT
admet-159	36	33	.	.	PUNCT
admet-159	37	1	previous	previous	ADJ
admet-159	37	2	findings	finding	NOUN
admet-159	37	3	in	in	ADP
admet-159	37	4	the	the	DET
admet-159	37	5	literature	literature	NOUN
admet-159	37	6	showed	show	VERB
admet-159	37	7	that	that	SCONJ
admet-159	37	8	the	the	DET
admet-159	37	9	choroid	choroid	NOUN
admet-159	37	10	plexus	plexus	NOUN
admet-159	37	11	accumulates	accumulate	VERB
admet-159	37	12	mn	mn	PROPN
admet-159	37	13	to	to	ADP
admet-159	37	14	a	a	DET
admet-159	37	15	great	great	ADJ
admet-159	37	16	extent	extent	NOUN
admet-159	37	17	after	after	ADP
admet-159	37	18	mn	mn	PROPN
admet-159	37	19	exposure	exposure	NOUN
admet-159	37	20	[	[	X
admet-159	37	21	22,33,34	22,33,34	NUM
admet-159	37	22	]	]	X
admet-159	37	23	.	.	PUNCT
admet-159	38	1	the	the	DET
admet-159	38	2	bcsfb	bcsfb	PROPN
admet-159	38	3	is	be	AUX
admet-159	38	4	known	know	VERB
admet-159	38	5	to	to	PART
admet-159	38	6	favor	favor	VERB
admet-159	38	7	mn	mn	PROPN
admet-159	38	8	influx	influx	VERB
admet-159	38	9	to	to	ADP
admet-159	38	10	the	the	DET
admet-159	38	11	brain	brain	NOUN
admet-159	38	12	with	with	ADP
admet-159	38	13	a	a	DET
admet-159	38	14	slow	slow	ADJ
admet-159	38	15	rate	rate	NOUN
admet-159	38	16	of	of	ADP
admet-159	38	17	mn	mn	PROPN
admet-159	38	18	efflux	efflux	VERB
admet-159	38	19	from	from	ADP
admet-159	38	20	the	the	DET
admet-159	38	21	csf	csf	NOUN
admet-159	39	1	[	[	X
admet-159	39	2	22,35,36	22,35,36	NUM
admet-159	39	3	]	]	PUNCT
admet-159	39	4	.	.	PUNCT
admet-159	40	1	this	this	PRON
admet-159	40	2	may	may	AUX
admet-159	40	3	contribute	contribute	VERB
admet-159	40	4	to	to	ADP
admet-159	40	5	the	the	DET
admet-159	40	6	high	high	ADJ
admet-159	40	7	mn	mn	PROPN
admet-159	40	8	storage	storage	NOUN
admet-159	40	9	and	and	CCONJ
admet-159	40	10	relatively	relatively	ADV
admet-159	40	11	long	long	ADJ
admet-159	40	12	half	half	ADJ
admet-159	40	13	-	-	PUNCT
admet-159	40	14	life	life	NOUN
admet-159	40	15	of	of	ADP
admet-159	40	16	mn	mn	PROPN
admet-159	40	17	in	in	ADP
admet-159	40	18	the	the	DET
admet-159	40	19	brain	brain	NOUN
admet-159	41	1	[	[	X
admet-159	41	2	37	37	NUM
admet-159	41	3	]	]	PUNCT
admet-159	41	4	.	.	PUNCT
admet-159	42	1	studies	study	NOUN
admet-159	42	2	have	have	AUX
admet-159	42	3	also	also	ADV
admet-159	42	4	indicated	indicate	VERB
admet-159	42	5	that	that	SCONJ
admet-159	42	6	mn	mn	PROPN
admet-159	42	7	can	can	AUX
admet-159	42	8	interact	interact	VERB
admet-159	42	9	with	with	ADP
admet-159	42	10	a	a	PRON
admet-159	42	11	-	-	PUNCT
admet-159	42	12	syn	syn	NOUN
admet-159	42	13	,	,	PUNCT
admet-159	42	14	promoting	promote	VERB
admet-159	42	15	the	the	DET
admet-159	42	16	aggregation	aggregation	NOUN
admet-159	42	17	of	of	ADP
admet-159	42	18	the	the	DET
admet-159	42	19	protein	protein	NOUN
admet-159	42	20	into	into	ADP
admet-159	42	21	oligomers	oligomer	NOUN
admet-159	42	22	in	in	ADP
admet-159	42	23	vitro	vitro	X
admet-159	43	1	[	[	X
admet-159	43	2	38,39	38,39	NOUN
admet-159	43	3	]	]	PUNCT
admet-159	43	4	and	and	CCONJ
admet-159	43	5	overexpression	overexpression	NOUN
admet-159	43	6	of	of	ADP
admet-159	43	7	a	a	DET
admet-159	43	8	-	-	PUNCT
admet-159	43	9	syn	syn	NOUN
admet-159	43	10	in	in	ADP
admet-159	43	11	pc12	pc12	PROPN
admet-159	43	12	and	and	CCONJ
admet-159	43	13	sh	sh	PROPN
admet-159	43	14	-	-	PUNCT
admet-159	43	15	sy5y	sy5y	PROPN
admet-159	43	16	cells	cell	NOUN
admet-159	43	17	[	[	X
admet-159	43	18	40,41	40,41	NOUN
admet-159	43	19	]	]	PUNCT
admet-159	43	20	.	.	PUNCT
admet-159	44	1	the	the	DET
admet-159	44	2	question	question	NOUN
admet-159	44	3	as	as	ADP
admet-159	44	4	to	to	ADP
admet-159	44	5	whether	whether	SCONJ
admet-159	44	6	or	or	CCONJ
admet-159	44	7	not	not	PART
admet-159	44	8	mn	mn	PROPN
admet-159	44	9	may	may	AUX
admet-159	44	10	interfere	interfere	VERB
admet-159	44	11	with	with	ADP
admet-159	44	12	a	a	DET
admet-159	44	13	-	-	PUNCT
admet-159	44	14	syn	syn	NOUN
admet-159	44	15	production	production	NOUN
admet-159	44	16	,	,	PUNCT
admet-159	44	17	aggregation	aggregation	NOUN
admet-159	44	18	and	and	CCONJ
admet-159	44	19	transport	transport	NOUN
admet-159	44	20	in	in	ADP
admet-159	44	21	the	the	DET
admet-159	44	22	bcsfb	bcsfb	NOUN
admet-159	44	23	remains	remain	VERB
admet-159	44	24	unanswered	unanswered	ADJ
admet-159	44	25	.	.	PUNCT
admet-159	45	1	the	the	DET
admet-159	45	2	purposes	purpose	NOUN
admet-159	45	3	of	of	ADP
admet-159	45	4	the	the	DET
admet-159	45	5	current	current	ADJ
admet-159	45	6	study	study	NOUN
admet-159	45	7	were	be	AUX
admet-159	45	8	to	to	ADP
admet-159	45	9	1	1	NUM
admet-159	45	10	)	)	PUNCT
admet-159	45	11	determine	determine	VERB
admet-159	45	12	the	the	DET
admet-159	45	13	endogenous	endogenous	ADJ
admet-159	45	14	expression	expression	NOUN
admet-159	45	15	of	of	ADP
admet-159	45	16	a	a	DET
admet-159	45	17	-	-	PUNCT
admet-159	45	18	syn	syn	NOUN
admet-159	45	19	in	in	ADP
admet-159	45	20	the	the	DET
admet-159	45	21	bcsfb	bcsfb	NOUN
admet-159	45	22	as	as	SCONJ
admet-159	45	23	affected	affect	VERB
admet-159	45	24	by	by	ADP
admet-159	45	25	mn	mn	PROPN
admet-159	45	26	exposure	exposure	NOUN
admet-159	45	27	,	,	PUNCT
admet-159	45	28	2	2	X
admet-159	45	29	)	)	PUNCT
admet-159	45	30	investigate	investigate	VERB
admet-159	45	31	the	the	DET
admet-159	45	32	uptake	uptake	NOUN
admet-159	45	33	of	of	ADP
admet-159	45	34	a	a	DET
admet-159	45	35	-	-	PUNCT
admet-159	45	36	syn	syn	NOUN
admet-159	45	37	by	by	ADP
admet-159	45	38	the	the	DET
admet-159	45	39	bcsfb	bcsfb	PROPN
admet-159	45	40	and	and	CCONJ
admet-159	45	41	the	the	DET
admet-159	45	42	effect	effect	NOUN
admet-159	45	43	of	of	ADP
admet-159	45	44	mn	mn	PROPN
admet-159	45	45	exposure	exposure	NOUN
admet-159	45	46	,	,	PUNCT
admet-159	45	47	3	3	X
admet-159	45	48	)	)	PUNCT
admet-159	45	49	study	study	VERB
admet-159	45	50	the	the	DET
admet-159	45	51	direct	direct	ADJ
admet-159	45	52	interaction	interaction	NOUN
admet-159	45	53	between	between	ADP
admet-159	45	54	mn	mn	PROPN
admet-159	45	55	and	and	CCONJ
admet-159	45	56	a	a	PROPN
admet-159	45	57	-	-	PUNCT
admet-159	45	58	syn	syn	NOUN
admet-159	45	59	in	in	ADP
admet-159	45	60	a	a	DET
admet-159	45	61	cell	cell	NOUN
admet-159	45	62	-	-	PUNCT
admet-159	45	63	free	free	ADJ
admet-159	45	64	system	system	NOUN
admet-159	45	65	,	,	PUNCT
admet-159	45	66	and	and	CCONJ
admet-159	45	67	4	4	X
admet-159	45	68	)	)	PUNCT
admet-159	45	69	explore	explore	VERB
admet-159	45	70	the	the	DET
admet-159	45	71	directional	directional	ADJ
admet-159	45	72	transport	transport	NOUN
admet-159	45	73	properties	property	NOUN
admet-159	45	74	of	of	ADP
admet-159	45	75	wild	wild	ADJ
admet-159	45	76	-	-	PUNCT
admet-159	45	77	type	type	NOUN
admet-159	45	78	a	a	DET
admet-159	45	79	-	-	PUNCT
admet-159	45	80	syn	syn	NOUN
admet-159	45	81	monomer	monomer	NOUN
admet-159	45	82	by	by	ADP
admet-159	45	83	the	the	DET
admet-159	45	84	bcsfb	bcsfb	NOUN
admet-159	45	85	and	and	CCONJ
admet-159	45	86	effects	effect	NOUN
admet-159	45	87	of	of	ADP
admet-159	45	88	mn	mn	PROPN
admet-159	45	89	exposure	exposure	NOUN
admet-159	45	90	.	.	PUNCT
admet-159	46	1	the	the	DET
admet-159	46	2	findings	finding	NOUN
admet-159	46	3	of	of	ADP
admet-159	46	4	these	these	DET
admet-159	46	5	works	work	NOUN
admet-159	46	6	establish	establish	VERB
admet-159	46	7	a	a	DET
admet-159	46	8	foundation	foundation	NOUN
admet-159	46	9	for	for	ADP
admet-159	46	10	understanding	understand	VERB
admet-159	46	11	the	the	DET
admet-159	46	12	role	role	NOUN
admet-159	46	13	of	of	ADP
admet-159	46	14	the	the	DET
admet-159	46	15	bcsfb	bcsfb	NOUN
admet-159	46	16	in	in	ADP
admet-159	46	17	regulating	regulate	VERB
admet-159	46	18	a	a	DET
admet-159	46	19	-	-	PUNCT
admet-159	46	20	syn	syn	NOUN
admet-159	46	21	homeostasis	homeostasis	NOUN
admet-159	46	22	in	in	ADP
admet-159	46	23	the	the	DET
admet-159	46	24	brain	brain	NOUN
admet-159	46	25	,	,	PUNCT
admet-159	46	26	the	the	DET
admet-159	46	27	effects	effect	NOUN
admet-159	46	28	of	of	ADP
admet-159	46	29	toxic	toxic	ADJ
admet-159	46	30	mn	mn	PROPN
admet-159	46	31	exposure	exposure	NOUN
admet-159	46	32	,	,	PUNCT
admet-159	46	33	and	and	CCONJ
admet-159	46	34	the	the	DET
admet-159	46	35	potential	potential	ADJ
admet-159	46	36	implications	implication	NOUN
admet-159	46	37	of	of	ADP
admet-159	46	38	these	these	DET
admet-159	46	39	relationships	relationship	NOUN
admet-159	46	40	in	in	ADP
admet-159	46	41	parkinsonian	parkinsonian	ADJ
admet-159	46	42	disorders	disorder	NOUN
admet-159	46	43	.	.	PUNCT
admet-159	47	1	admet	admet	PROPN
admet-159	47	2	&	&	CCONJ
admet-159	47	3	dmpk	dmpk	PROPN
admet-159	47	4	3(1	3(1	NUM
admet-159	47	5	)	)	PUNCT
admet-159	47	6	(	(	PUNCT
admet-159	47	7	2015	2015	NUM
admet-159	47	8	)	)	PUNCT
admet-159	47	9	15	15	NUM
admet-159	47	10	-	-	SYM
admet-159	47	11	33	33	NUM
admet-159	47	12	effects	effect	NOUN
admet-159	47	13	of	of	ADP
admet-159	47	14	manganese	manganese	ADJ
admet-159	47	15	exposure	exposure	NOUN
admet-159	47	16	on	on	ADP
admet-159	47	17	expression	expression	NOUN
admet-159	47	18	and	and	CCONJ
admet-159	47	19	transport	transport	NOUN
admet-159	47	20	of	of	ADP
admet-159	47	21	-synuclein	-synuclein	PROPN
admet-159	47	22	doi	doi	NOUN
admet-159	47	23	:	:	PUNCT
admet-159	47	24	10.5599	10.5599	NUM
admet-159	47	25	/	/	SYM
admet-159	47	26	admet.3.1.159	admet.3.1.159	NUM
admet-159	47	27	17	17	NUM
admet-159	47	28	experimental	experimental	ADJ
admet-159	47	29	materials	material	NOUN
admet-159	47	30	chemicals	chemical	NOUN
admet-159	47	31	and	and	CCONJ
admet-159	47	32	reagents	reagent	NOUN
admet-159	47	33	were	be	AUX
admet-159	47	34	acquired	acquire	VERB
admet-159	47	35	from	from	ADP
admet-159	47	36	the	the	DET
admet-159	47	37	following	follow	VERB
admet-159	47	38	sources	source	NOUN
admet-159	47	39	:	:	PUNCT
admet-159	47	40	mn	mn	PROPN
admet-159	47	41	chloride	chloride	PROPN
admet-159	47	42	tetrahydrate	tetrahydrate	NOUN
admet-159	47	43	(	(	PUNCT
admet-159	47	44	mncl2•4h2o	mncl2•4h2o	X
admet-159	47	45	)	)	PUNCT
admet-159	47	46	from	from	ADP
admet-159	47	47	fisher	fisher	PROPN
admet-159	47	48	scientific	scientific	PROPN
admet-159	47	49	(	(	PUNCT
admet-159	47	50	pittsburgh	pittsburgh	PROPN
admet-159	47	51	,	,	PUNCT
admet-159	47	52	pa	pa	PROPN
admet-159	47	53	)	)	PUNCT
admet-159	47	54	;	;	PUNCT
admet-159	47	55	sodium	sodium	NOUN
admet-159	47	56	chloride	chloride	NOUN
admet-159	47	57	(	(	PUNCT
admet-159	47	58	nacl	nacl	NOUN
admet-159	47	59	)	)	PUNCT
admet-159	47	60	from	from	ADP
admet-159	47	61	avantor	avantor	NOUN
admet-159	47	62	performance	performance	NOUN
admet-159	47	63	materials	material	NOUN
admet-159	47	64	(	(	PUNCT
admet-159	47	65	center	center	NOUN
admet-159	47	66	valley	valley	NOUN
admet-159	47	67	,	,	PUNCT
admet-159	47	68	pa	pa	PROPN
admet-159	47	69	)	)	PUNCT
admet-159	47	70	;	;	PUNCT
admet-159	47	71	sodium	sodium	NOUN
admet-159	47	72	phosphate	phosphate	NOUN
admet-159	47	73	(	(	PUNCT
admet-159	47	74	na2hpo4	na2hpo4	PROPN
admet-159	47	75	)	)	PUNCT
admet-159	47	76	,	,	PUNCT
admet-159	47	77	potassium	potassium	NOUN
admet-159	47	78	chloride	chloride	NOUN
admet-159	47	79	(	(	PUNCT
admet-159	47	80	kcl	kcl	NOUN
admet-159	47	81	)	)	PUNCT
admet-159	47	82	,	,	PUNCT
admet-159	47	83	and	and	CCONJ
admet-159	47	84	potassium	potassium	NOUN
admet-159	47	85	phosphate	phosphate	NOUN
admet-159	47	86	(	(	PUNCT
admet-159	47	87	kh2po4	kh2po4	NOUN
admet-159	47	88	)	)	PUNCT
admet-159	47	89	from	from	ADP
admet-159	47	90	mallinckrodt	mallinckrodt	PROPN
admet-159	47	91	chemicals	chemical	NOUN
admet-159	47	92	(	(	PUNCT
admet-159	47	93	phillipsburg	phillipsburg	PROPN
admet-159	47	94	,	,	PUNCT
admet-159	47	95	nj	nj	PROPN
admet-159	47	96	)	)	PUNCT
admet-159	47	97	;	;	PUNCT
admet-159	47	98	copper	copper	NOUN
admet-159	47	99	chloride	chloride	NOUN
admet-159	47	100	(	(	PUNCT
admet-159	47	101	cucl2	cucl2	NOUN
admet-159	47	102	)	)	PUNCT
admet-159	47	103	,	,	PUNCT
admet-159	47	104	paraformaldehyde	paraformaldehyde	NOUN
admet-159	47	105	(	(	PUNCT
admet-159	47	106	pfa	pfa	PROPN
admet-159	47	107	)	)	PUNCT
admet-159	47	108	,	,	PUNCT
admet-159	47	109	phenylmethylsulfonyl	phenylmethylsulfonyl	NOUN
admet-159	47	110	fluoride	fluoride	NOUN
admet-159	47	111	(	(	PUNCT
admet-159	47	112	pmsf	pmsf	NOUN
admet-159	47	113	)	)	PUNCT
admet-159	47	114	,	,	PUNCT
admet-159	47	115	epidermal	epidermal	ADJ
admet-159	47	116	growth	growth	NOUN
admet-159	47	117	factor	factor	NOUN
admet-159	47	118	(	(	PUNCT
admet-159	47	119	egf	egf	PROPN
admet-159	47	120	)	)	PUNCT
admet-159	47	121	,	,	PUNCT
admet-159	47	122	cis-4hydroxyl	cis-4hydroxyl	NOUN
admet-159	47	123	-	-	ADJ
admet-159	47	124	l	l	NOUN
admet-159	47	125	-	-	NOUN
admet-159	47	126	proline	proline	NOUN
admet-159	47	127	(	(	PUNCT
admet-159	47	128	cis	cis	NOUN
admet-159	47	129	-	-	PUNCT
admet-159	47	130	hp	hp	NOUN
admet-159	47	131	)	)	PUNCT
admet-159	47	132	,	,	PUNCT
admet-159	47	133	0.25	0.25	NUM
admet-159	47	134	%	%	NOUN
admet-159	47	135	trypsin	trypsin	NOUN
admet-159	47	136	-	-	PUNCT
admet-159	47	137	edta	edta	NOUN
admet-159	47	138	from	from	ADP
admet-159	47	139	sigma	sigma	PROPN
admet-159	47	140	(	(	PUNCT
admet-159	47	141	st	st	PROPN
admet-159	47	142	.	.	PROPN
admet-159	47	143	louis	louis	PROPN
admet-159	47	144	,	,	PUNCT
admet-159	47	145	mo	mo	PROPN
admet-159	47	146	)	)	PUNCT
admet-159	47	147	;	;	PUNCT
admet-159	47	148	hank	hank	PROPN
admet-159	47	149	’s	’s	PART
admet-159	47	150	balanced	balanced	ADJ
admet-159	47	151	salt	salt	NOUN
admet-159	47	152	solution	solution	NOUN
admet-159	47	153	(	(	PUNCT
admet-159	47	154	hbss	hbss	NOUN
admet-159	47	155	)	)	PUNCT
admet-159	47	156	,	,	PUNCT
admet-159	47	157	fluor	fluor	NOUN
admet-159	47	158	alexa-555	alexa-555	NOUN
admet-159	47	159	conjugated	conjugate	VERB
admet-159	47	160	goat	goat	PROPN
admet-159	47	161	anti	anti	PROPN
admet-159	47	162	-	-	ADJ
admet-159	47	163	mouse	mouse	ADJ
admet-159	47	164	secondary	secondary	ADJ
admet-159	47	165	antibody	antibody	NOUN
admet-159	47	166	,	,	PUNCT
admet-159	47	167	fluor	fluor	NOUN
admet-159	47	168	alexa-488	alexa-488	NOUN
admet-159	47	169	conjugated	conjugated	PROPN
admet-159	47	170	goat	goat	PROPN
admet-159	47	171	anti	anti	ADJ
admet-159	47	172	-	-	ADJ
admet-159	47	173	rabbit	rabbit	ADJ
admet-159	47	174	secondary	secondary	ADJ
admet-159	47	175	antibody	antibody	NOUN
admet-159	47	176	,	,	PUNCT
admet-159	47	177	trizol	trizol	PROPN
admet-159	47	178	reagent	reagent	ADJ
admet-159	47	179	,	,	PUNCT
admet-159	47	180	collagen	collagen	NOUN
admet-159	48	1	i	i	PRON
admet-159	48	2	(	(	PUNCT
admet-159	48	3	rat	rat	NOUN
admet-159	48	4	tail	tail	NOUN
admet-159	48	5	)	)	PUNCT
admet-159	48	6	,	,	PUNCT
admet-159	48	7	fetal	fetal	ADJ
admet-159	48	8	bovine	bovine	NOUN
admet-159	48	9	serum	serum	NOUN
admet-159	48	10	(	(	PUNCT
admet-159	48	11	fbs	fbs	PROPN
admet-159	48	12	)	)	PUNCT
admet-159	48	13	,	,	PUNCT
admet-159	48	14	penicillin	penicillin	NOUN
admet-159	48	15	,	,	PUNCT
admet-159	48	16	streptomycin	streptomycin	PROPN
admet-159	48	17	,	,	PUNCT
admet-159	48	18	amphotericin	amphotericin	PROPN
admet-159	48	19	,	,	PUNCT
admet-159	48	20	gentamycin	gentamycin	VERB
admet-159	48	21	,	,	PUNCT
admet-159	48	22	and	and	CCONJ
admet-159	48	23	human	human	ADJ
admet-159	48	24	a	a	PROPN
admet-159	48	25	-	-	PUNCT
admet-159	48	26	syn	syn	NOUN
admet-159	48	27	elisa	elisa	PROPN
admet-159	48	28	kit	kit	NOUN
admet-159	48	29	from	from	ADP
admet-159	48	30	life	life	NOUN
admet-159	48	31	technologies	technology	NOUN
admet-159	48	32	(	(	PUNCT
admet-159	48	33	carlsbad	carlsbad	PROPN
admet-159	48	34	,	,	PUNCT
admet-159	48	35	ca	ca	NOUN
admet-159	48	36	)	)	PUNCT
admet-159	48	37	;	;	PUNCT
admet-159	48	38	fetal	fetal	ADJ
admet-159	48	39	bovine	bovine	NOUN
admet-159	48	40	serum	serum	NOUN
admet-159	48	41	(	(	PUNCT
admet-159	48	42	fbs	fbs	PROPN
admet-159	48	43	)	)	PUNCT
admet-159	48	44	,	,	PUNCT
admet-159	48	45	and	and	CCONJ
admet-159	48	46	dulbecco	dulbecco	NOUN
admet-159	48	47	’s	’s	PART
admet-159	48	48	modified	modified	PROPN
admet-159	48	49	eagle	eagle	PROPN
admet-159	48	50	’s	’s	PART
admet-159	48	51	medium	medium	NOUN
admet-159	48	52	(	(	PUNCT
admet-159	48	53	dmem	dmem	ADJ
admet-159	48	54	)	)	PUNCT
admet-159	48	55	from	from	ADP
admet-159	48	56	cellgro	cellgro	PROPN
admet-159	48	57	(	(	PUNCT
admet-159	48	58	manassas	manassas	PROPN
admet-159	48	59	,	,	PUNCT
admet-159	48	60	va	va	PROPN
admet-159	48	61	)	)	PUNCT
admet-159	48	62	;	;	PUNCT
admet-159	48	63	pronase	pronase	NOUN
admet-159	48	64	,	,	PUNCT
admet-159	48	65	protease	protease	NOUN
admet-159	48	66	,	,	PUNCT
admet-159	48	67	and	and	CCONJ
admet-159	48	68	protease	protease	NOUN
admet-159	48	69	inhibitor	inhibitor	NOUN
admet-159	48	70	cocktail	cocktail	NOUN
admet-159	48	71	from	from	ADP
admet-159	48	72	calbiochem	calbiochem	NOUN
admet-159	48	73	(	(	PUNCT
admet-159	48	74	san	san	PROPN
admet-159	48	75	diego	diego	PROPN
admet-159	48	76	,	,	PUNCT
admet-159	48	77	ca	ca	NOUN
admet-159	48	78	)	)	PUNCT
admet-159	48	79	;	;	PUNCT
admet-159	48	80	sodium	sodium	NOUN
admet-159	48	81	dodecyl	dodecyl	PROPN
admet-159	48	82	sulfate	sulfate	NOUN
admet-159	48	83	(	(	PUNCT
admet-159	48	84	sds	sds	PROPN
admet-159	48	85	)	)	PUNCT
admet-159	48	86	,	,	PUNCT
admet-159	48	87	triton	triton	PROPN
admet-159	48	88	x-100	x-100	PROPN
admet-159	48	89	,	,	PUNCT
admet-159	48	90	cdna	cdna	PROPN
admet-159	48	91	synthesis	synthesis	NOUN
admet-159	48	92	kit	kit	NOUN
admet-159	48	93	,	,	PUNCT
admet-159	48	94	and	and	CCONJ
admet-159	48	95	itaq	itaq	PROPN
admet-159	48	96	universal	universal	ADJ
admet-159	48	97	sybr	sybr	PROPN
admet-159	48	98	green	green	ADJ
admet-159	48	99	supermix	supermix	PROPN
admet-159	48	100	from	from	ADP
admet-159	48	101	bio	bio	NOUN
admet-159	48	102	-	-	PROPN
admet-159	48	103	rad	rad	PROPN
admet-159	48	104	(	(	PUNCT
admet-159	48	105	hercules	hercules	PROPN
admet-159	48	106	,	,	PUNCT
admet-159	48	107	ca	ca	NOUN
admet-159	48	108	)	)	PUNCT
admet-159	48	109	;	;	PUNCT
admet-159	48	110	collagen	collagen	NOUN
admet-159	48	111	-	-	PUNCT
admet-159	48	112	coated	coat	VERB
admet-159	48	113	transwell	transwell	NOUN
admet-159	48	114	-	-	PUNCT
admet-159	48	115	col	col	NOUN
admet-159	48	116	inserts	insert	NOUN
admet-159	48	117	from	from	ADP
admet-159	48	118	corning	corn	VERB
admet-159	48	119	(	(	PUNCT
admet-159	48	120	cambridge	cambridge	PROPN
admet-159	48	121	,	,	PUNCT
admet-159	48	122	ma	ma	PROPN
admet-159	48	123	)	)	PUNCT
admet-159	48	124	;	;	PUNCT
admet-159	48	125	rabbit	rabbit	NOUN
admet-159	48	126	polyclonal	polyclonal	ADJ
admet-159	48	127	asyn	asyn	ADJ
admet-159	48	128	primary	primary	ADJ
admet-159	48	129	antibody	antibody	NOUN
admet-159	48	130	from	from	ADP
admet-159	48	131	cell	cell	NOUN
admet-159	48	132	signaling	signal	VERB
admet-159	48	133	technologies	technology	NOUN
admet-159	48	134	(	(	PUNCT
admet-159	48	135	2642s	2642s	NUM
admet-159	48	136	)	)	PUNCT
admet-159	48	137	(	(	PUNCT
admet-159	48	138	danvers	danver	NOUN
admet-159	48	139	,	,	PUNCT
admet-159	48	140	ma	ma	PROPN
admet-159	48	141	)	)	PUNCT
admet-159	48	142	.	.	PUNCT
admet-159	49	1	all	all	DET
admet-159	49	2	reagents	reagent	NOUN
admet-159	49	3	were	be	AUX
admet-159	49	4	of	of	ADP
admet-159	49	5	analytical	analytical	ADJ
admet-159	49	6	grade	grade	NOUN
admet-159	49	7	,	,	PUNCT
admet-159	49	8	hplc	hplc	NOUN
admet-159	49	9	grade	grade	NOUN
admet-159	49	10	,	,	PUNCT
admet-159	49	11	or	or	CCONJ
admet-159	49	12	the	the	DET
admet-159	49	13	best	good	ADJ
admet-159	49	14	pharmaceutical	pharmaceutical	ADJ
admet-159	49	15	grade	grade	NOUN
admet-159	49	16	available	available	ADJ
admet-159	49	17	.	.	PUNCT
admet-159	50	1	cell	cell	NOUN
admet-159	50	2	cultures	culture	NOUN
admet-159	50	3	and	and	CCONJ
admet-159	50	4	treatments	treatment	VERB
admet-159	50	5	the	the	DET
admet-159	50	6	choroidal	choroidal	ADJ
admet-159	50	7	epithelial	epithelial	ADJ
admet-159	50	8	z310	z310	PROPN
admet-159	50	9	cell	cell	NOUN
admet-159	50	10	line	line	NOUN
admet-159	50	11	was	be	AUX
admet-159	50	12	derived	derive	VERB
admet-159	50	13	from	from	ADP
admet-159	50	14	rodent	rodent	ADJ
admet-159	50	15	choroid	choroid	NOUN
admet-159	50	16	plexus	plexus	NOUN
admet-159	50	17	by	by	ADP
admet-159	50	18	this	this	DET
admet-159	50	19	laboratory	laboratory	NOUN
admet-159	50	20	;	;	PUNCT
admet-159	50	21	the	the	DET
admet-159	50	22	culturing	culture	VERB
admet-159	50	23	and	and	CCONJ
admet-159	50	24	maintenance	maintenance	NOUN
admet-159	50	25	procedures	procedure	NOUN
admet-159	50	26	of	of	ADP
admet-159	50	27	this	this	DET
admet-159	50	28	cell	cell	NOUN
admet-159	50	29	line	line	NOUN
admet-159	50	30	have	have	AUX
admet-159	50	31	been	be	AUX
admet-159	50	32	previously	previously	ADV
admet-159	50	33	described	describe	VERB
admet-159	50	34	[	[	PUNCT
admet-159	50	35	42	42	NUM
admet-159	50	36	-	-	SYM
admet-159	50	37	44	44	NUM
admet-159	50	38	]	]	PUNCT
admet-159	50	39	.	.	PUNCT
admet-159	51	1	z310	z310	PROPN
admet-159	51	2	cells	cell	NOUN
admet-159	51	3	were	be	AUX
admet-159	51	4	grown	grow	VERB
admet-159	51	5	in	in	ADP
admet-159	51	6	dmem	dmem	ADJ
admet-159	51	7	medium	medium	NOUN
admet-159	51	8	supplemented	supplement	VERB
admet-159	51	9	with	with	ADP
admet-159	51	10	10	10	NUM
admet-159	51	11	%	%	NOUN
admet-159	51	12	fbs	fbs	PROPN
admet-159	51	13	,	,	PUNCT
admet-159	51	14	100	100	NUM
admet-159	51	15	u	u	NOUN
admet-159	51	16	/	/	SYM
admet-159	51	17	ml	ml	ADP
admet-159	51	18	penicillin	penicillin	PROPN
admet-159	51	19	-	-	PUNCT
admet-159	51	20	streptomycin	streptomycin	PROPN
admet-159	51	21	,	,	PUNCT
admet-159	51	22	100	100	NUM
admet-159	51	23	μg	μg	NOUN
admet-159	51	24	/	/	SYM
admet-159	51	25	ml	ml	X
admet-159	51	26	gentamicin	gentamicin	VERB
admet-159	51	27	sulfate	sulfate	NOUN
admet-159	51	28	,	,	PUNCT
admet-159	51	29	and	and	CCONJ
admet-159	51	30	10	10	NUM
admet-159	51	31	ng	ng	PROPN
admet-159	51	32	/	/	SYM
admet-159	51	33	ml	ml	X
admet-159	51	34	egf	egf	PROPN
admet-159	51	35	,	,	PUNCT
admet-159	51	36	in	in	ADP
admet-159	51	37	a	a	DET
admet-159	51	38	humidified	humidified	ADJ
admet-159	51	39	incubator	incubator	NOUN
admet-159	51	40	with	with	ADP
admet-159	51	41	95	95	NUM
admet-159	51	42	%	%	NOUN
admet-159	51	43	air-5	air-5	PUNCT
admet-159	51	44	%	%	NOUN
admet-159	51	45	co2	co2	NOUN
admet-159	51	46	at	at	ADP
admet-159	51	47	37	37	NUM
admet-159	51	48	°	°	NOUN
admet-159	51	49	c	c	NOUN
admet-159	51	50	.	.	NOUN
admet-159	52	1	0.25	0.25	NUM
admet-159	52	2	%	%	NOUN
admet-159	52	3	trypsin	trypsin	NOUN
admet-159	52	4	-	-	PUNCT
admet-159	52	5	edta	edta	NOUN
admet-159	52	6	was	be	AUX
admet-159	52	7	used	use	VERB
admet-159	52	8	to	to	PART
admet-159	52	9	dissociate	dissociate	VERB
admet-159	52	10	cells	cell	NOUN
admet-159	52	11	during	during	ADP
admet-159	52	12	maintenance	maintenance	NOUN
admet-159	52	13	.	.	PUNCT
admet-159	53	1	z310	z310	PROPN
admet-159	53	2	cells	cell	NOUN
admet-159	53	3	were	be	AUX
admet-159	53	4	passaged	passage	VERB
admet-159	53	5	twice	twice	ADV
admet-159	53	6	a	a	DET
admet-159	53	7	week	week	NOUN
admet-159	53	8	.	.	PUNCT
admet-159	54	1	for	for	ADP
admet-159	54	2	culturing	culture	VERB
admet-159	54	3	primary	primary	ADJ
admet-159	54	4	choroidal	choroidal	ADJ
admet-159	54	5	epithelial	epithelial	ADJ
admet-159	54	6	cells	cell	NOUN
admet-159	54	7	from	from	ADP
admet-159	54	8	rats	rat	NOUN
admet-159	54	9	,	,	PUNCT
admet-159	54	10	male	male	ADJ
admet-159	54	11	sprague	sprague	NOUN
admet-159	54	12	-	-	PUNCT
admet-159	54	13	dawley	dawley	NOUN
admet-159	54	14	rats	rat	NOUN
admet-159	54	15	(	(	PUNCT
admet-159	54	16	3	3	NUM
admet-159	54	17	-	-	PUNCT
admet-159	54	18	week	week	NOUN
admet-159	54	19	old	old	ADJ
admet-159	54	20	,	,	PUNCT
admet-159	54	21	35	35	NUM
admet-159	54	22	-	-	SYM
admet-159	54	23	49	49	NUM
admet-159	54	24	g	g	NOUN
admet-159	54	25	)	)	PUNCT
admet-159	54	26	were	be	AUX
admet-159	54	27	used	use	VERB
admet-159	54	28	.	.	PUNCT
admet-159	55	1	rats	rat	NOUN
admet-159	55	2	were	be	AUX
admet-159	55	3	purchased	purchase	VERB
admet-159	55	4	from	from	ADP
admet-159	55	5	harlan	harlan	PROPN
admet-159	55	6	laboratories	laboratories	PROPN
admet-159	55	7	(	(	PUNCT
admet-159	55	8	indianapolis	indianapolis	PROPN
admet-159	55	9	,	,	PUNCT
admet-159	55	10	in	in	ADP
admet-159	55	11	)	)	PUNCT
admet-159	55	12	and	and	CCONJ
admet-159	55	13	euthanized	euthanize	VERB
admet-159	55	14	with	with	ADP
admet-159	55	15	co2	co2	NOUN
admet-159	55	16	.	.	PUNCT
admet-159	56	1	choroid	choroid	NOUN
admet-159	56	2	plexuses	plexus	NOUN
admet-159	56	3	from	from	ADP
admet-159	56	4	the	the	DET
admet-159	56	5	lateral	lateral	ADJ
admet-159	56	6	and	and	CCONJ
admet-159	56	7	third	third	ADJ
admet-159	56	8	ventricles	ventricle	NOUN
admet-159	56	9	were	be	AUX
admet-159	56	10	dissected	dissect	VERB
admet-159	56	11	,	,	PUNCT
admet-159	56	12	minced	mince	VERB
admet-159	56	13	down	down	ADP
admet-159	56	14	to	to	ADP
admet-159	56	15	cubes	cube	NOUN
admet-159	56	16	1	1	NUM
admet-159	56	17	mm	mm	NOUN
admet-159	56	18	in	in	ADP
admet-159	56	19	length	length	NOUN
admet-159	56	20	,	,	PUNCT
admet-159	56	21	and	and	CCONJ
admet-159	56	22	digested	digest	VERB
admet-159	56	23	in	in	ADP
admet-159	56	24	1	1	NUM
admet-159	56	25	ml	ml	NOUN
admet-159	56	26	hbss	hbss	NOUN
admet-159	56	27	containing	contain	VERB
admet-159	56	28	0.2	0.2	NUM
admet-159	56	29	%	%	NOUN
admet-159	56	30	pronase	pronase	NOUN
admet-159	56	31	at	at	ADP
admet-159	56	32	37	37	NUM
admet-159	56	33	°	°	NOUN
admet-159	56	34	c	c	NOUN
admet-159	56	35	for	for	ADP
admet-159	56	36	5	5	NUM
admet-159	56	37	-	-	SYM
admet-159	56	38	10	10	NUM
admet-159	56	39	min	min	NOUN
admet-159	56	40	.	.	PUNCT
admet-159	56	41	digestion	digestion	NOUN
admet-159	56	42	was	be	AUX
admet-159	56	43	stopped	stop	VERB
admet-159	56	44	by	by	ADP
admet-159	56	45	adding	add	VERB
admet-159	56	46	4	4	NUM
admet-159	56	47	ml	ml	NOUN
admet-159	56	48	of	of	ADP
admet-159	56	49	hbss	hbss	NOUN
admet-159	56	50	.	.	PUNCT
admet-159	57	1	cells	cell	NOUN
admet-159	57	2	were	be	AUX
admet-159	57	3	pelleted	pellete	VERB
admet-159	57	4	via	via	ADP
admet-159	57	5	centrifugation	centrifugation	NOUN
admet-159	57	6	(	(	PUNCT
admet-159	57	7	800	800	NUM
admet-159	57	8	x	x	SYM
admet-159	57	9	g	g	NOUN
admet-159	57	10	for	for	ADP
admet-159	57	11	5	5	NUM
admet-159	57	12	min	min	NOUN
admet-159	57	13	)	)	PUNCT
admet-159	57	14	,	,	PUNCT
admet-159	57	15	washed	wash	VERB
admet-159	57	16	with	with	ADP
admet-159	57	17	fresh	fresh	ADJ
admet-159	57	18	hbss	hbss	NOUN
admet-159	57	19	,	,	PUNCT
admet-159	57	20	and	and	CCONJ
admet-159	57	21	centrifuged	centrifuge	VERB
admet-159	57	22	again	again	ADV
admet-159	57	23	(	(	PUNCT
admet-159	57	24	800	800	NUM
admet-159	57	25	x	x	SYM
admet-159	57	26	g	g	NOUN
admet-159	57	27	for	for	ADP
admet-159	57	28	5	5	NUM
admet-159	57	29	min	min	NOUN
admet-159	57	30	)	)	PUNCT
admet-159	57	31	.	.	PUNCT
admet-159	58	1	cells	cell	NOUN
admet-159	58	2	were	be	AUX
admet-159	58	3	passed	pass	VERB
admet-159	58	4	13	13	NUM
admet-159	58	5	-	-	SYM
admet-159	58	6	14	14	NUM
admet-159	58	7	times	time	NOUN
admet-159	58	8	through	through	ADP
admet-159	58	9	a	a	DET
admet-159	58	10	20	20	NUM
admet-159	58	11	-	-	PUNCT
admet-159	58	12	gauge	gauge	NOUN
admet-159	58	13	needle	needle	NOUN
admet-159	58	14	attached	attach	VERB
admet-159	58	15	to	to	ADP
admet-159	58	16	a	a	DET
admet-159	58	17	10	10	NUM
admet-159	58	18	ml	ml	NOUN
admet-159	58	19	syringe	syringe	NOUN
admet-159	58	20	and	and	CCONJ
admet-159	58	21	counted	count	VERB
admet-159	58	22	,	,	PUNCT
admet-159	58	23	seeded	seed	VERB
admet-159	58	24	on	on	ADP
admet-159	58	25	wells	well	NOUN
admet-159	58	26	pre	pre	VERB
admet-159	58	27	-	-	VERB
admet-159	58	28	coated	coated	ADJ
admet-159	58	29	with	with	ADP
admet-159	58	30	collagen	collagen	NOUN
admet-159	58	31	(	(	PUNCT
admet-159	58	32	gibco	gibco	NOUN
admet-159	58	33	/	/	SYM
admet-159	58	34	life	life	NOUN
admet-159	58	35	technologies	technology	NOUN
admet-159	58	36	cat	cat	NOUN
admet-159	58	37	.	.	PUNCT
admet-159	59	1	no	no	INTJ
admet-159	59	2	.	.	PUNCT
admet-159	60	1	a1048301	a1048301	PROPN
admet-159	60	2	)	)	PUNCT
admet-159	60	3	,	,	PUNCT
admet-159	61	1	and	and	CCONJ
admet-159	61	2	incubated	incubate	VERB
admet-159	61	3	at	at	ADP
admet-159	61	4	37	37	NUM
admet-159	61	5	°	°	NOUN
admet-159	61	6	c	c	NOUN
admet-159	61	7	with	with	ADP
admet-159	61	8	95	95	NUM
admet-159	61	9	%	%	NOUN
admet-159	61	10	air-5	air-5	PUNCT
admet-159	61	11	%	%	NOUN
admet-159	61	12	co2	co2	NOUN
admet-159	61	13	for	for	ADP
admet-159	61	14	2	2	NUM
admet-159	61	15	-	-	SYM
admet-159	61	16	3	3	NUM
admet-159	61	17	days	day	NOUN
admet-159	61	18	without	without	ADP
admet-159	61	19	disturbing	disturb	VERB
admet-159	61	20	.	.	PUNCT
admet-159	62	1	medium	medium	NOUN
admet-159	62	2	was	be	AUX
admet-159	62	3	replaced	replace	VERB
admet-159	62	4	every	every	DET
admet-159	62	5	other	other	ADJ
admet-159	62	6	day	day	NOUN
admet-159	62	7	with	with	ADP
admet-159	62	8	a	a	DET
admet-159	62	9	fresh	fresh	ADJ
admet-159	62	10	growth	growth	NOUN
admet-159	62	11	medium	medium	NOUN
admet-159	62	12	.	.	PUNCT
admet-159	63	1	on	on	ADP
admet-159	63	2	the	the	DET
admet-159	63	3	4th	4th	ADJ
admet-159	63	4	day	day	NOUN
admet-159	63	5	,	,	PUNCT
admet-159	63	6	cells	cell	NOUN
admet-159	63	7	were	be	AUX
admet-159	63	8	cultured	cultured	ADJ
admet-159	63	9	with	with	ADP
admet-159	63	10	the	the	DET
admet-159	63	11	growth	growth	NOUN
admet-159	63	12	medium	medium	NOUN
admet-159	63	13	supplemented	supplement	VERB
admet-159	63	14	with	with	ADP
admet-159	63	15	25	25	NUM
admet-159	63	16	μg	μg	NOUN
admet-159	63	17	/	/	SYM
admet-159	63	18	ml	ml	NOUN
admet-159	63	19	cis	cis	NOUN
admet-159	63	20	-	-	NOUN
admet-159	63	21	hp	hp	ADJ
admet-159	63	22	to	to	PART
admet-159	63	23	inhibit	inhibit	VERB
admet-159	63	24	the	the	DET
admet-159	63	25	growth	growth	NOUN
admet-159	63	26	of	of	ADP
admet-159	63	27	fibroblastic	fibroblastic	ADJ
admet-159	63	28	cells	cell	NOUN
admet-159	63	29	.	.	PUNCT
admet-159	64	1	this	this	DET
admet-159	64	2	protocol	protocol	NOUN
admet-159	64	3	has	have	AUX
admet-159	64	4	been	be	AUX
admet-159	64	5	used	use	VERB
admet-159	64	6	extensively	extensively	ADV
admet-159	64	7	in	in	ADP
admet-159	64	8	previous	previous	ADJ
admet-159	64	9	research	research	NOUN
admet-159	64	10	performed	perform	VERB
admet-159	64	11	by	by	ADP
admet-159	64	12	this	this	DET
admet-159	64	13	lab	lab	NOUN
admet-159	65	1	[	[	X
admet-159	65	2	27,29,45	27,29,45	NUM
admet-159	65	3	-	-	SYM
admet-159	65	4	47	47	NUM
admet-159	65	5	]	]	PUNCT
admet-159	65	6	.	.	PUNCT
admet-159	66	1	autoclaved	autoclaved	PROPN
admet-159	66	2	25	25	NUM
admet-159	66	3	mm	mm	NOUN
admet-159	66	4	mncl2	mncl2	NOUN
admet-159	66	5	and	and	CCONJ
admet-159	66	6	25	25	NUM
admet-159	66	7	mm	mm	PROPN
admet-159	66	8	cucl2	cucl2	NOUN
admet-159	66	9	stock	stock	NOUN
admet-159	66	10	solutions	solution	NOUN
admet-159	66	11	were	be	AUX
admet-159	66	12	prepared	prepare	VERB
admet-159	66	13	by	by	ADP
admet-159	66	14	dissolving	dissolve	VERB
admet-159	66	15	mncl2•4h2o	mncl2•4h2o	NOUN
admet-159	66	16	and	and	CCONJ
admet-159	66	17	cucl2	cucl2	NOUN
admet-159	66	18	in	in	ADP
admet-159	66	19	sterile	sterile	ADJ
admet-159	66	20	,	,	PUNCT
admet-159	66	21	double	double	ADJ
admet-159	66	22	-	-	PUNCT
admet-159	66	23	deionized	deionize	VERB
admet-159	66	24	water	water	NOUN
admet-159	66	25	,	,	PUNCT
admet-159	66	26	respectively	respectively	ADV
admet-159	66	27	.	.	PUNCT
admet-159	67	1	z310	z310	PROPN
admet-159	67	2	cells	cell	NOUN
admet-159	67	3	were	be	AUX
admet-159	67	4	treated	treat	VERB
admet-159	67	5	with	with	ADP
admet-159	67	6	50	50	NUM
admet-159	67	7	or	or	CCONJ
admet-159	67	8	100	100	NUM
admet-159	67	9	μm	μm	NUM
admet-159	67	10	mncl2	mncl2	NOUN
admet-159	67	11	or	or	CCONJ
admet-159	67	12	cucl2	cucl2	NOUN
admet-159	67	13	for	for	ADP
admet-159	67	14	24	24	NUM
admet-159	67	15	h	h	NOUN
admet-159	67	16	,	,	PUNCT
admet-159	67	17	or	or	CCONJ
admet-159	67	18	100	100	NUM
admet-159	67	19	μm	μm	NUM
admet-159	67	20	mncl2	mncl2	NOUN
admet-159	67	21	for	for	ADP
admet-159	67	22	24	24	NUM
admet-159	67	23	and	and	CCONJ
admet-159	67	24	48	48	NUM
admet-159	67	25	h	h	NOUN
admet-159	67	26	for	for	ADP
admet-159	67	27	the	the	DET
admet-159	67	28	immunohistochemical	immunohistochemical	ADJ
admet-159	67	29	studies	study	NOUN
admet-159	67	30	.	.	PUNCT
admet-159	68	1	z310	z310	PROPN
admet-159	68	2	cells	cell	NOUN
admet-159	68	3	were	be	AUX
admet-159	68	4	treated	treat	VERB
admet-159	68	5	with	with	ADP
admet-159	68	6	25	25	NUM
admet-159	68	7	,	,	PUNCT
admet-159	68	8	50	50	NUM
admet-159	68	9	,	,	PUNCT
admet-159	68	10	or	or	CCONJ
admet-159	68	11	100	100	NUM
admet-159	68	12	μm	μm	NUM
admet-159	68	13	mncl2	mncl2	NOUN
admet-159	68	14	for	for	ADP
admet-159	68	15	24	24	NUM
admet-159	68	16	h	h	NOUN
admet-159	68	17	for	for	ADP
admet-159	68	18	the	the	DET
admet-159	68	19	quantitative	quantitative	ADJ
admet-159	68	20	rt	rt	ADJ
admet-159	68	21	-	-	PUNCT
admet-159	68	22	pcr	pcr	ADJ
admet-159	68	23	study	study	NOUN
admet-159	68	24	.	.	PUNCT
admet-159	69	1	the	the	DET
admet-159	69	2	dose	dose	NOUN
admet-159	69	3	regimen	regimen	PROPN
admet-159	69	4	,	,	PUNCT
admet-159	69	5	used	use	VERB
admet-159	69	6	in	in	ADP
admet-159	69	7	the	the	DET
admet-159	69	8	following	follow	VERB
admet-159	69	9	studies	study	NOUN
admet-159	69	10	,	,	PUNCT
admet-159	69	11	was	be	AUX
admet-159	69	12	chosen	choose	VERB
admet-159	69	13	according	accord	VERB
admet-159	69	14	to	to	ADP
admet-159	69	15	previous	previous	ADJ
admet-159	69	16	research	research	NOUN
admet-159	69	17	performed	perform	VERB
admet-159	69	18	in	in	ADP
admet-159	69	19	this	this	DET
admet-159	69	20	lab	lab	NOUN
admet-159	69	21	or	or	CCONJ
admet-159	69	22	by	by	ADP
admet-159	69	23	other	other	ADJ
admet-159	69	24	groups	group	NOUN
admet-159	69	25	[	[	X
admet-159	69	26	27,29,42,48	27,29,42,48	NUM
admet-159	69	27	]	]	PUNCT
admet-159	69	28	.	.	PUNCT
admet-159	70	1	bates	bates	PROPN
admet-159	70	2	et	et	PROPN
admet-159	70	3	al	al	PROPN
admet-159	70	4	.	.	PROPN
admet-159	70	5	admet	admet	PROPN
admet-159	70	6	&	&	CCONJ
admet-159	70	7	dmpk	dmpk	PROPN
admet-159	70	8	3(1	3(1	NUM
admet-159	70	9	)	)	PUNCT
admet-159	70	10	(	(	PUNCT
admet-159	70	11	2015	2015	NUM
admet-159	70	12	)	)	PUNCT
admet-159	70	13	15	15	NUM
admet-159	70	14	-	-	SYM
admet-159	70	15	33	33	NUM
admet-159	70	16	18	18	NUM
admet-159	70	17	immunohistochemical	immunohistochemical	ADJ
admet-159	70	18	(	(	PUNCT
admet-159	70	19	ihc	ihc	PROPN
admet-159	70	20	)	)	PUNCT
admet-159	70	21	staining	stain	VERB
admet-159	70	22	freshly	freshly	ADV
admet-159	70	23	harvested	harvest	VERB
admet-159	70	24	choroid	choroid	NOUN
admet-159	70	25	plexus	plexus	NOUN
admet-159	70	26	tissues	tissue	NOUN
admet-159	70	27	were	be	AUX
admet-159	70	28	immediately	immediately	ADV
admet-159	70	29	fixed	fix	VERB
admet-159	70	30	with	with	ADP
admet-159	70	31	4	4	NUM
admet-159	70	32	%	%	NOUN
admet-159	70	33	paraformaldehyde	paraformaldehyde	NOUN
admet-159	70	34	(	(	PUNCT
admet-159	70	35	ph	ph	NOUN
admet-159	70	36	7.4	7.4	NUM
admet-159	70	37	)	)	PUNCT
admet-159	70	38	for	for	ADP
admet-159	70	39	10	10	NUM
admet-159	70	40	min	min	NOUN
admet-159	70	41	,	,	PUNCT
admet-159	70	42	permeabilized	permeabilize	VERB
admet-159	70	43	with	with	ADP
admet-159	70	44	0.1	0.1	NUM
admet-159	70	45	%	%	NOUN
admet-159	70	46	triton	triton	PROPN
admet-159	70	47	x-100	x-100	PROPN
admet-159	70	48	,	,	PUNCT
admet-159	70	49	and	and	CCONJ
admet-159	70	50	blocked	block	VERB
admet-159	70	51	in	in	ADP
admet-159	70	52	1	1	NUM
admet-159	70	53	%	%	NOUN
admet-159	70	54	bovine	bovine	NOUN
admet-159	70	55	serum	serum	NOUN
admet-159	70	56	albumin	albumin	PROPN
admet-159	70	57	(	(	PUNCT
admet-159	70	58	bsa	bsa	PROPN
admet-159	70	59	)	)	PUNCT
admet-159	70	60	at	at	ADP
admet-159	70	61	room	room	NOUN
admet-159	70	62	temperature	temperature	NOUN
admet-159	70	63	for	for	ADP
admet-159	70	64	1	1	NUM
admet-159	70	65	h.	h.	PROPN
admet-159	70	66	tissues	tissue	NOUN
admet-159	70	67	were	be	AUX
admet-159	70	68	washed	wash	VERB
admet-159	70	69	three	three	NUM
admet-159	70	70	times	time	NOUN
admet-159	70	71	with	with	ADP
admet-159	70	72	pbs	pbs	PROPN
admet-159	70	73	(	(	PUNCT
admet-159	70	74	10	10	NUM
admet-159	70	75	min	min	NOUN
admet-159	70	76	/	/	SYM
admet-159	70	77	wash	wash	NOUN
admet-159	70	78	)	)	PUNCT
admet-159	70	79	after	after	ADP
admet-159	70	80	the	the	DET
admet-159	70	81	fixing	fixing	NOUN
admet-159	70	82	and	and	CCONJ
admet-159	70	83	permeabilizing	permeabilize	VERB
admet-159	70	84	steps	step	NOUN
admet-159	70	85	.	.	PUNCT
admet-159	71	1	tissues	tissue	NOUN
admet-159	71	2	were	be	AUX
admet-159	71	3	incubated	incubate	VERB
admet-159	71	4	with	with	ADP
admet-159	71	5	polyclonal	polyclonal	ADJ
admet-159	71	6	rabbit	rabbit	NOUN
admet-159	71	7	anti	anti	ADJ
admet-159	71	8	-	-	ADJ
admet-159	71	9	a	a	DET
admet-159	71	10	-	-	PUNCT
admet-159	71	11	syn	syn	NOUN
admet-159	71	12	antibody	antibody	NOUN
admet-159	71	13	(	(	PUNCT
admet-159	71	14	1:100	1:100	NUM
admet-159	71	15	)	)	PUNCT
admet-159	71	16	in	in	ADP
admet-159	71	17	1	1	NUM
admet-159	71	18	%	%	NOUN
admet-159	71	19	bsa	bsa	NOUN
admet-159	71	20	at	at	ADP
admet-159	71	21	4	4	NUM
admet-159	71	22	°	°	ADP
admet-159	71	23	c	c	NOUN
admet-159	71	24	for	for	ADP
admet-159	71	25	48	48	NUM
admet-159	71	26	h	h	NOUN
admet-159	71	27	,	,	PUNCT
admet-159	71	28	followed	follow	VERB
admet-159	71	29	by	by	ADP
admet-159	71	30	repeated	repeat	VERB
admet-159	71	31	washes	wash	NOUN
admet-159	71	32	with	with	ADP
admet-159	71	33	pbs	pbs	PROPN
admet-159	71	34	(	(	PUNCT
admet-159	71	35	3	3	NUM
admet-159	71	36	x	x	SYM
admet-159	71	37	10	10	NUM
admet-159	71	38	min	min	NOUN
admet-159	71	39	/	/	SYM
admet-159	71	40	wash	wash	NOUN
admet-159	71	41	)	)	PUNCT
admet-159	71	42	,	,	PUNCT
admet-159	71	43	and	and	CCONJ
admet-159	71	44	then	then	ADV
admet-159	71	45	incubated	incubate	VERB
admet-159	71	46	with	with	ADP
admet-159	71	47	alexa	alexa	NOUN
admet-159	71	48	fluor	fluor	NOUN
admet-159	71	49	-488	-488	PROPN
admet-159	71	50	conjugated	conjugate	VERB
admet-159	71	51	goat	goat	PROPN
admet-159	71	52	anti	anti	ADJ
admet-159	71	53	-	-	ADJ
admet-159	71	54	rabbit	rabbit	ADJ
admet-159	71	55	secondary	secondary	ADJ
admet-159	71	56	antibody	antibody	NOUN
admet-159	71	57	(	(	PUNCT
admet-159	71	58	1:1000	1:1000	NUM
admet-159	71	59	)	)	PUNCT
admet-159	71	60	in	in	ADP
admet-159	71	61	1	1	NUM
admet-159	71	62	%	%	NOUN
admet-159	71	63	bsa	bsa	PROPN
admet-159	71	64	at	at	ADP
admet-159	71	65	room	room	NOUN
admet-159	71	66	temperature	temperature	NOUN
admet-159	71	67	for	for	ADP
admet-159	71	68	1	1	NUM
admet-159	71	69	h.	h.	PROPN
admet-159	71	70	tissues	tissue	NOUN
admet-159	71	71	were	be	AUX
admet-159	71	72	rinsed	rinse	VERB
admet-159	71	73	with	with	ADP
admet-159	71	74	pbs	pbs	PROPN
admet-159	71	75	(	(	PUNCT
admet-159	71	76	3	3	NUM
admet-159	71	77	x	x	SYM
admet-159	71	78	10	10	NUM
admet-159	71	79	min	min	NOUN
admet-159	71	80	/	/	SYM
admet-159	71	81	wash	wash	NOUN
admet-159	71	82	)	)	PUNCT
admet-159	71	83	and	and	CCONJ
admet-159	71	84	then	then	ADV
admet-159	71	85	mounted	mount	VERB
admet-159	71	86	to	to	ADP
admet-159	71	87	the	the	DET
admet-159	71	88	objective	objective	ADJ
admet-159	71	89	slides	slide	NOUN
admet-159	71	90	using	use	VERB
admet-159	71	91	prolong	prolong	ADJ
admet-159	71	92	gold	gold	ADJ
admet-159	71	93	anti	anti	ADJ
admet-159	71	94	-	-	ADJ
admet-159	71	95	fade	fade	ADJ
admet-159	71	96	reagent	reagent	NOUN
admet-159	71	97	(	(	PUNCT
admet-159	71	98	life	life	NOUN
admet-159	71	99	technologies	technology	NOUN
admet-159	71	100	,	,	PUNCT
admet-159	71	101	carlsbad	carlsbad	PROPN
admet-159	71	102	,	,	PUNCT
admet-159	71	103	ca	ca	NOUN
admet-159	71	104	)	)	PUNCT
admet-159	71	105	to	to	PART
admet-159	71	106	prevent	prevent	VERB
admet-159	71	107	fluorescent	fluorescent	ADJ
admet-159	71	108	bleaching	bleaching	NOUN
admet-159	71	109	for	for	ADP
admet-159	71	110	confocal	confocal	ADJ
admet-159	71	111	microscopy	microscopy	NOUN
admet-159	71	112	examination	examination	NOUN
admet-159	71	113	.	.	PUNCT
admet-159	72	1	glass	glass	NOUN
admet-159	72	2	coverslips	coverslip	NOUN
admet-159	72	3	(	(	PUNCT
admet-159	72	4	0.17	0.17	NUM
admet-159	72	5	mm	mm	NOUN
admet-159	72	6	in	in	ADP
admet-159	72	7	thickness	thickness	NOUN
admet-159	72	8	)	)	PUNCT
admet-159	72	9	were	be	AUX
admet-159	72	10	sterilized	sterilize	VERB
admet-159	72	11	with	with	ADP
admet-159	72	12	75	75	NUM
admet-159	72	13	%	%	NOUN
admet-159	72	14	ethanol	ethanol	NOUN
admet-159	72	15	.	.	PUNCT
admet-159	73	1	z310	z310	PROPN
admet-159	73	2	cells	cell	NOUN
admet-159	73	3	were	be	AUX
admet-159	73	4	seeded	seed	VERB
admet-159	73	5	on	on	ADP
admet-159	73	6	glass	glass	NOUN
admet-159	73	7	coverslips	coverslip	NOUN
admet-159	73	8	at	at	ADP
admet-159	73	9	a	a	DET
admet-159	73	10	density	density	NOUN
admet-159	73	11	of	of	ADP
admet-159	73	12	2	2	NUM
admet-159	73	13	x	x	SYM
admet-159	73	14	105	105	NUM
admet-159	73	15	/	/	SYM
admet-159	73	16	well	well	ADV
admet-159	73	17	in	in	ADP
admet-159	73	18	a	a	DET
admet-159	73	19	6	6	NUM
admet-159	73	20	-	-	PUNCT
admet-159	73	21	well	well	NOUN
admet-159	73	22	-	-	PUNCT
admet-159	73	23	plate	plate	NOUN
admet-159	73	24	.	.	PUNCT
admet-159	74	1	rat	rat	NOUN
admet-159	74	2	plexus	plexus	NOUN
admet-159	74	3	primary	primary	ADJ
admet-159	74	4	cells	cell	NOUN
admet-159	74	5	were	be	AUX
admet-159	74	6	seeded	seed	VERB
admet-159	74	7	on	on	ADP
admet-159	74	8	glass	glass	NOUN
admet-159	74	9	coverslips	coverslip	NOUN
admet-159	74	10	at	at	ADP
admet-159	74	11	a	a	DET
admet-159	74	12	density	density	NOUN
admet-159	74	13	of	of	ADP
admet-159	74	14	5	5	NUM
admet-159	74	15	x	x	SYM
admet-159	74	16	10	10	NUM
admet-159	74	17	4	4	NUM
admet-159	74	18	/well	/well	NOUN
admet-159	74	19	in	in	ADP
admet-159	74	20	a	a	DET
admet-159	74	21	24	24	NUM
admet-159	74	22	-	-	PUNCT
admet-159	74	23	well	well	NOUN
admet-159	74	24	plate	plate	NOUN
admet-159	74	25	and	and	CCONJ
admet-159	74	26	allowed	allow	VERB
admet-159	74	27	to	to	PART
admet-159	74	28	grow	grow	VERB
admet-159	74	29	for	for	ADP
admet-159	74	30	24	24	NUM
admet-159	74	31	h	h	NOUN
admet-159	74	32	to	to	PART
admet-159	74	33	achieve	achieve	VERB
admet-159	74	34	50	50	NUM
admet-159	74	35	%	%	NOUN
admet-159	74	36	confluence	confluence	NOUN
admet-159	74	37	,	,	PUNCT
admet-159	74	38	and	and	CCONJ
admet-159	74	39	then	then	ADV
admet-159	74	40	treated	treat	VERB
admet-159	74	41	with	with	ADP
admet-159	74	42	100	100	NUM
admet-159	74	43	μm	μm	NUM
admet-159	74	44	mncl2	mncl2	NOUN
admet-159	74	45	for	for	ADP
admet-159	74	46	12	12	NUM
admet-159	74	47	,	,	PUNCT
admet-159	74	48	24	24	NUM
admet-159	74	49	,	,	PUNCT
admet-159	74	50	or	or	CCONJ
admet-159	74	51	48	48	NUM
admet-159	74	52	h.	h.	NOUN
admet-159	74	53	at	at	ADP
admet-159	74	54	the	the	DET
admet-159	74	55	end	end	NOUN
admet-159	74	56	of	of	ADP
admet-159	74	57	treatment	treatment	NOUN
admet-159	74	58	,	,	PUNCT
admet-159	74	59	cells	cell	NOUN
admet-159	74	60	were	be	AUX
admet-159	74	61	fixed	fix	VERB
admet-159	74	62	in	in	ADP
admet-159	74	63	4	4	NUM
admet-159	74	64	%	%	NOUN
admet-159	74	65	paraformaldehyde	paraformaldehyde	NOUN
admet-159	74	66	and	and	CCONJ
admet-159	74	67	permeabilized	permeabilize	VERB
admet-159	74	68	in	in	ADP
admet-159	74	69	0.1	0.1	NUM
admet-159	74	70	%	%	NOUN
admet-159	74	71	triton	triton	PROPN
admet-159	74	72	x-100	x-100	PROPN
admet-159	75	1	at	at	ADP
admet-159	75	2	room	room	NOUN
admet-159	75	3	temperature	temperature	NOUN
admet-159	75	4	and	and	CCONJ
admet-159	75	5	washed	wash	VERB
admet-159	75	6	with	with	ADP
admet-159	75	7	pbs	pbs	PROPN
admet-159	75	8	(	(	PUNCT
admet-159	75	9	3	3	NUM
admet-159	75	10	x	x	SYM
admet-159	75	11	5	5	NUM
admet-159	75	12	min	min	NOUN
admet-159	75	13	/	/	SYM
admet-159	75	14	wash	wash	NOUN
admet-159	75	15	)	)	PUNCT
admet-159	75	16	after	after	ADP
admet-159	75	17	the	the	DET
admet-159	75	18	fixing	fixing	NOUN
admet-159	75	19	and	and	CCONJ
admet-159	75	20	permeating	permeate	VERB
admet-159	75	21	steps	step	NOUN
admet-159	75	22	.	.	PUNCT
admet-159	76	1	cells	cell	NOUN
admet-159	76	2	were	be	AUX
admet-159	76	3	then	then	ADV
admet-159	76	4	blocked	block	VERB
admet-159	76	5	with	with	ADP
admet-159	76	6	1	1	NUM
admet-159	76	7	%	%	NOUN
admet-159	76	8	bsa	bsa	NOUN
admet-159	76	9	for	for	SCONJ
admet-159	76	10	1	1	NUM
admet-159	76	11	h	h	NOUN
admet-159	76	12	at	at	ADP
admet-159	76	13	room	room	NOUN
admet-159	76	14	temperature	temperature	NOUN
admet-159	76	15	followed	follow	VERB
admet-159	76	16	by	by	ADP
admet-159	76	17	incubation	incubation	NOUN
admet-159	76	18	with	with	ADP
admet-159	76	19	rabbit	rabbit	NOUN
admet-159	76	20	polyclonal	polyclonal	ADJ
admet-159	76	21	a	a	PROPN
admet-159	76	22	-	-	PUNCT
admet-159	76	23	syn	syn	NOUN
admet-159	76	24	antibody	antibody	NOUN
admet-159	76	25	(	(	PUNCT
admet-159	76	26	1:1000	1:1000	X
admet-159	76	27	)	)	PUNCT
admet-159	76	28	at	at	ADP
admet-159	76	29	4	4	NUM
admet-159	76	30	°	°	ADP
admet-159	76	31	c	c	NOUN
admet-159	76	32	for	for	ADP
admet-159	76	33	48	48	NUM
admet-159	76	34	h.	h.	NOUN
admet-159	76	35	cells	cell	NOUN
admet-159	76	36	were	be	AUX
admet-159	76	37	washed	wash	VERB
admet-159	76	38	with	with	ADP
admet-159	76	39	pbs	pbs	PROPN
admet-159	76	40	(	(	PUNCT
admet-159	76	41	3	3	NUM
admet-159	76	42	x	x	SYM
admet-159	76	43	5	5	NUM
admet-159	76	44	min	min	NOUN
admet-159	76	45	/	/	SYM
admet-159	76	46	wash	wash	NOUN
admet-159	76	47	)	)	PUNCT
admet-159	76	48	before	before	ADP
admet-159	76	49	being	be	AUX
admet-159	76	50	incubated	incubate	VERB
admet-159	76	51	in	in	ADP
admet-159	76	52	alexa	alexa	PROPN
admet-159	76	53	fluor-488	fluor-488	PROPN
admet-159	77	1	conjugated	conjugate	VERB
admet-159	77	2	goat	goat	PROPN
admet-159	77	3	anti	anti	ADJ
admet-159	77	4	-	-	ADJ
admet-159	77	5	rabbit	rabbit	ADJ
admet-159	77	6	secondary	secondary	ADJ
admet-159	77	7	antibody	antibody	NOUN
admet-159	77	8	(	(	PUNCT
admet-159	77	9	1:1000	1:1000	NUM
admet-159	77	10	)	)	PUNCT
admet-159	77	11	for	for	ADP
admet-159	77	12	24	24	NUM
admet-159	77	13	h.	h.	PROPN
admet-159	77	14	glass	glass	NOUN
admet-159	77	15	coverslips	coverslip	NOUN
admet-159	77	16	were	be	AUX
admet-159	77	17	mounted	mount	VERB
admet-159	77	18	to	to	ADP
admet-159	77	19	objective	objective	ADJ
admet-159	77	20	slides	slide	NOUN
admet-159	77	21	for	for	ADP
admet-159	77	22	confocal	confocal	ADJ
admet-159	77	23	microscopy	microscopy	NOUN
admet-159	77	24	observation	observation	NOUN
admet-159	77	25	.	.	PUNCT
admet-159	78	1	slides	slide	NOUN
admet-159	78	2	were	be	AUX
admet-159	78	3	prepared	prepare	VERB
admet-159	78	4	using	use	VERB
admet-159	78	5	gold	gold	ADJ
admet-159	78	6	anti	anti	ADJ
admet-159	78	7	-	-	ADJ
admet-159	78	8	fade	fade	ADJ
admet-159	78	9	to	to	PART
admet-159	78	10	avoid	avoid	VERB
admet-159	78	11	fluorescent	fluorescent	ADJ
admet-159	78	12	bleaching	bleaching	NOUN
admet-159	78	13	for	for	ADP
admet-159	78	14	confocal	confocal	ADJ
admet-159	78	15	microscopic	microscopic	ADJ
admet-159	78	16	examination	examination	NOUN
admet-159	78	17	.	.	PUNCT
admet-159	79	1	all	all	DET
admet-159	79	2	slides	slide	NOUN
admet-159	79	3	were	be	AUX
admet-159	79	4	dried	dry	VERB
admet-159	79	5	in	in	ADP
admet-159	79	6	a	a	DET
admet-159	79	7	hood	hood	NOUN
admet-159	79	8	,	,	PUNCT
admet-159	79	9	with	with	ADP
admet-159	79	10	no	no	DET
admet-159	79	11	exposure	exposure	NOUN
admet-159	79	12	to	to	ADP
admet-159	79	13	light	light	NOUN
admet-159	79	14	,	,	PUNCT
admet-159	79	15	at	at	ADP
admet-159	79	16	room	room	NOUN
admet-159	79	17	temperature	temperature	NOUN
admet-159	79	18	overnight	overnight	ADV
admet-159	79	19	.	.	PUNCT
admet-159	80	1	the	the	DET
admet-159	80	2	negative	negative	ADJ
admet-159	80	3	control	control	NOUN
admet-159	80	4	was	be	AUX
admet-159	80	5	established	establish	VERB
admet-159	80	6	by	by	ADP
admet-159	80	7	using	use	VERB
admet-159	80	8	only	only	ADV
admet-159	80	9	the	the	DET
admet-159	80	10	secondary	secondary	ADJ
admet-159	80	11	antibody	antibody	NOUN
admet-159	80	12	to	to	PART
admet-159	80	13	reflect	reflect	VERB
admet-159	80	14	non	non	ADJ
admet-159	80	15	-	-	ADJ
admet-159	80	16	specific	specific	ADJ
admet-159	80	17	staining	staining	NOUN
admet-159	80	18	on	on	ADP
admet-159	80	19	the	the	DET
admet-159	80	20	background	background	NOUN
admet-159	80	21	.	.	PUNCT
admet-159	81	1	confocal	confocal	ADJ
admet-159	81	2	microscopy	microscopy	NOUN
admet-159	81	3	and	and	CCONJ
admet-159	81	4	quantification	quantification	NOUN
admet-159	81	5	to	to	PART
admet-159	81	6	acquire	acquire	VERB
admet-159	81	7	images	image	NOUN
admet-159	81	8	,	,	PUNCT
admet-159	81	9	pre	pre	ADJ
admet-159	81	10	-	-	ADJ
admet-159	81	11	dried	dried	ADJ
admet-159	81	12	slides	slide	NOUN
admet-159	81	13	containing	contain	VERB
admet-159	81	14	experimental	experimental	ADJ
admet-159	81	15	specimens	specimen	NOUN
admet-159	81	16	were	be	AUX
admet-159	81	17	mounted	mount	VERB
admet-159	81	18	on	on	ADP
admet-159	81	19	the	the	DET
admet-159	81	20	stage	stage	NOUN
admet-159	81	21	of	of	ADP
admet-159	81	22	a	a	DET
admet-159	81	23	nikon	nikon	ADJ
admet-159	81	24	inverted	inverted	ADJ
admet-159	81	25	confocal	confocal	ADJ
admet-159	81	26	laser	laser	NOUN
admet-159	81	27	-	-	PUNCT
admet-159	81	28	scanning	scan	VERB
admet-159	81	29	microscope	microscope	NOUN
admet-159	81	30	and	and	CCONJ
admet-159	81	31	viewed	view	VERB
admet-159	81	32	through	through	ADP
admet-159	81	33	a	a	DET
admet-159	81	34	60x	60x	NUM
admet-159	81	35	oil	oil	NOUN
admet-159	81	36	-	-	PUNCT
admet-159	81	37	immersion	immersion	NOUN
admet-159	81	38	objective	objective	NOUN
admet-159	81	39	(	(	PUNCT
admet-159	81	40	plan	plan	NOUN
admet-159	81	41	apo	apo	PROPN
admet-159	81	42	,	,	PUNCT
admet-159	81	43	60x/1.40	60x/1.40	NUM
admet-159	81	44	oil	oil	NOUN
admet-159	81	45	,	,	PUNCT
admet-159	81	46	∞	∞	PROPN
admet-159	81	47	0.17	0.17	NUM
admet-159	81	48	,	,	PUNCT
admet-159	81	49	dic	dic	ADJ
admet-159	81	50	)	)	PUNCT
admet-159	81	51	,	,	PUNCT
admet-159	81	52	with	with	ADP
admet-159	81	53	a	a	DET
admet-159	81	54	488	488	NUM
admet-159	81	55	-	-	PUNCT
admet-159	81	56	nm	nm	NOUN
admet-159	81	57	laser	laser	NOUN
admet-159	81	58	and	and	CCONJ
admet-159	81	59	a	a	DET
admet-159	81	60	562	562	NUM
admet-159	81	61	-	-	PUNCT
admet-159	81	62	nm	nm	NOUN
admet-159	81	63	laser	laser	NOUN
admet-159	81	64	source	source	NOUN
admet-159	81	65	for	for	ADP
admet-159	81	66	excitation	excitation	NOUN
admet-159	81	67	.	.	PUNCT
admet-159	82	1	lower	low	ADJ
admet-159	82	2	laser	laser	NOUN
admet-159	82	3	intensity	intensity	NOUN
admet-159	82	4	was	be	AUX
admet-159	82	5	used	use	VERB
admet-159	82	6	to	to	PART
admet-159	82	7	avoid	avoid	VERB
admet-159	82	8	photo	photo	ADJ
admet-159	82	9	bleaching	bleaching	NOUN
admet-159	82	10	.	.	PUNCT
admet-159	83	1	each	each	DET
admet-159	83	2	slide	slide	NOUN
admet-159	83	3	was	be	AUX
admet-159	83	4	examined	examine	VERB
admet-159	83	5	under	under	ADP
admet-159	83	6	reduced	reduce	VERB
admet-159	83	7	transmitted	transmit	VERB
admet-159	83	8	-	-	PUNCT
admet-159	83	9	light	light	NOUN
admet-159	83	10	illumination	illumination	NOUN
admet-159	83	11	;	;	PUNCT
admet-159	83	12	the	the	DET
admet-159	83	13	area	area	NOUN
admet-159	83	14	containing	contain	VERB
admet-159	83	15	undamaged	undamaged	ADJ
admet-159	83	16	epithelium	epithelium	NOUN
admet-159	83	17	with	with	ADP
admet-159	83	18	underlying	underlie	VERB
admet-159	83	19	vasculature	vasculature	NOUN
admet-159	83	20	was	be	AUX
admet-159	83	21	chosen	choose	VERB
admet-159	83	22	for	for	ADP
admet-159	83	23	analyses	analysis	NOUN
admet-159	83	24	.	.	PUNCT
admet-159	84	1	approximately	approximately	ADV
admet-159	84	2	10	10	NUM
admet-159	84	3	-	-	SYM
admet-159	84	4	20	20	NUM
admet-159	84	5	areas	area	NOUN
admet-159	84	6	of	of	ADP
admet-159	84	7	epithelium	epithelium	NOUN
admet-159	84	8	were	be	AUX
admet-159	84	9	selected	select	VERB
admet-159	84	10	for	for	ADP
admet-159	84	11	image	image	NOUN
admet-159	84	12	collection	collection	NOUN
admet-159	84	13	and	and	CCONJ
admet-159	84	14	analysis	analysis	NOUN
admet-159	84	15	.	.	PUNCT
admet-159	85	1	image	image	NOUN
admet-159	85	2	data	datum	NOUN
admet-159	85	3	reported	report	VERB
admet-159	85	4	were	be	AUX
admet-159	85	5	the	the	DET
admet-159	85	6	results	result	NOUN
admet-159	85	7	of	of	ADP
admet-159	85	8	a	a	DET
admet-159	85	9	single	single	ADJ
admet-159	85	10	experiment	experiment	NOUN
admet-159	85	11	representative	representative	NOUN
admet-159	85	12	of	of	ADP
admet-159	85	13	three	three	NUM
admet-159	85	14	to	to	PART
admet-159	85	15	four	four	NUM
admet-159	85	16	experiments	experiment	NOUN
admet-159	85	17	.	.	PUNCT
admet-159	86	1	images	image	NOUN
admet-159	86	2	were	be	AUX
admet-159	86	3	scanned	scan	VERB
admet-159	86	4	with	with	ADP
admet-159	86	5	the	the	DET
admet-159	86	6	nikon	nikon	PROPN
admet-159	86	7	ez	ez	PROPN
admet-159	86	8	-	-	PROPN
admet-159	86	9	c1	c1	PROPN
admet-159	86	10	(	(	PUNCT
admet-159	86	11	version	version	NOUN
admet-159	86	12	3.90	3.90	NUM
admet-159	86	13	)	)	PUNCT
admet-159	86	14	confocal	confocal	ADJ
admet-159	86	15	imaging	imaging	NOUN
admet-159	86	16	program	program	NOUN
admet-159	86	17	.	.	PUNCT
admet-159	87	1	signal	signal	PROPN
admet-159	87	2	intensities	intensity	NOUN
admet-159	87	3	were	be	AUX
admet-159	87	4	quantified	quantify	VERB
admet-159	87	5	using	use	VERB
admet-159	87	6	the	the	DET
admet-159	87	7	nis	nis	NOUN
admet-159	87	8	-	-	PUNCT
admet-159	87	9	elements	element	NOUN
admet-159	87	10	br	br	NOUN
admet-159	87	11	(	(	PUNCT
admet-159	87	12	version	version	NOUN
admet-159	87	13	3.10	3.10	NUM
admet-159	87	14	)	)	PUNCT
admet-159	87	15	program	program	NOUN
admet-159	87	16	.	.	PUNCT
admet-159	88	1	each	each	DET
admet-159	88	2	cell	cell	NOUN
admet-159	88	3	or	or	CCONJ
admet-159	88	4	group	group	NOUN
admet-159	88	5	of	of	ADP
admet-159	88	6	cells	cell	NOUN
admet-159	88	7	was	be	AUX
admet-159	88	8	isolated	isolate	VERB
admet-159	88	9	as	as	ADP
admet-159	88	10	a	a	DET
admet-159	88	11	region	region	NOUN
admet-159	88	12	of	of	ADP
admet-159	88	13	interest	interest	NOUN
admet-159	88	14	(	(	PUNCT
admet-159	88	15	roi	roi	NOUN
admet-159	88	16	)	)	PUNCT
admet-159	88	17	.	.	PUNCT
admet-159	89	1	cells	cell	NOUN
admet-159	89	2	that	that	PRON
admet-159	89	3	were	be	AUX
admet-159	89	4	partially	partially	ADV
admet-159	89	5	imaged	image	VERB
admet-159	89	6	within	within	ADP
admet-159	89	7	the	the	DET
admet-159	89	8	image	image	NOUN
admet-159	89	9	frame	frame	NOUN
admet-159	89	10	were	be	AUX
admet-159	89	11	excluded	exclude	VERB
admet-159	89	12	to	to	PART
admet-159	89	13	improve	improve	VERB
admet-159	89	14	accuracy	accuracy	NOUN
admet-159	89	15	and	and	CCONJ
admet-159	89	16	reliability	reliability	NOUN
admet-159	89	17	of	of	ADP
admet-159	89	18	quantification	quantification	NOUN
admet-159	89	19	.	.	PUNCT
admet-159	90	1	mean	mean	NOUN
admet-159	90	2	intensity	intensity	NOUN
admet-159	90	3	values	value	NOUN
admet-159	90	4	were	be	AUX
admet-159	90	5	calculated	calculate	VERB
admet-159	90	6	as	as	ADP
admet-159	90	7	the	the	DET
admet-159	90	8	sum	sum	NOUN
admet-159	90	9	of	of	ADP
admet-159	90	10	intensities	intensity	NOUN
admet-159	90	11	within	within	ADP
admet-159	90	12	the	the	DET
admet-159	90	13	corresponding	corresponding	ADJ
admet-159	90	14	roi	roi	NOUN
admet-159	90	15	divided	divide	VERB
admet-159	90	16	by	by	ADP
admet-159	90	17	the	the	DET
admet-159	90	18	area	area	NOUN
admet-159	90	19	of	of	ADP
admet-159	90	20	the	the	DET
admet-159	90	21	roi	roi	NOUN
admet-159	90	22	.	.	PUNCT
admet-159	91	1	a	a	DET
admet-159	91	2	minimum	minimum	NOUN
admet-159	91	3	of	of	ADP
admet-159	91	4	three	three	NUM
admet-159	91	5	images	image	NOUN
admet-159	91	6	per	per	ADP
admet-159	91	7	treatment	treatment	NOUN
admet-159	91	8	group	group	NOUN
admet-159	91	9	was	be	AUX
admet-159	91	10	used	use	VERB
admet-159	91	11	for	for	ADP
admet-159	91	12	confocal	confocal	ADJ
admet-159	91	13	quantification	quantification	NOUN
admet-159	91	14	.	.	PUNCT
admet-159	92	1	a	a	DET
admet-159	92	2	-	-	PUNCT
admet-159	92	3	synuclein	synuclein	NOUN
admet-159	92	4	mrna	mrna	PROPN
admet-159	92	5	quantitation	quantitation	NOUN
admet-159	92	6	by	by	ADP
admet-159	92	7	quantitative	quantitative	ADJ
admet-159	92	8	real	real	ADJ
admet-159	92	9	-	-	PUNCT
admet-159	92	10	time	time	NOUN
admet-159	92	11	rt	rt	NOUN
admet-159	92	12	-	-	PUNCT
admet-159	92	13	pcr	pcr	ADJ
admet-159	92	14	(	(	PUNCT
admet-159	92	15	qpcr	qpcr	ADV
admet-159	92	16	)	)	PUNCT
admet-159	92	17	the	the	DET
admet-159	92	18	transcription	transcription	NOUN
admet-159	92	19	levels	level	NOUN
admet-159	92	20	of	of	ADP
admet-159	92	21	mrna	mrna	PROPN
admet-159	92	22	encoding	encode	VERB
admet-159	92	23	rat	rat	NOUN
admet-159	92	24	a	a	PROPN
admet-159	92	25	-	-	PUNCT
admet-159	92	26	syn	syn	NOUN
admet-159	92	27	(	(	PUNCT
admet-159	92	28	snca	snca	NOUN
admet-159	92	29	)	)	PUNCT
admet-159	92	30	were	be	AUX
admet-159	92	31	quantified	quantify	VERB
admet-159	92	32	using	use	VERB
admet-159	92	33	qpcr	qpcr	ADV
admet-159	92	34	.	.	PUNCT
admet-159	93	1	z310	z310	PROPN
admet-159	93	2	cells	cell	NOUN
admet-159	93	3	were	be	AUX
admet-159	93	4	seeded	seed	VERB
admet-159	93	5	and	and	CCONJ
admet-159	93	6	cultured	cultured	ADJ
admet-159	93	7	for	for	ADP
admet-159	93	8	24	24	NUM
admet-159	93	9	h	h	NOUN
admet-159	93	10	prior	prior	ADV
admet-159	93	11	to	to	ADP
admet-159	93	12	incubation	incubation	NOUN
admet-159	93	13	with	with	ADP
admet-159	93	14	25	25	NUM
admet-159	93	15	,	,	PUNCT
admet-159	93	16	50	50	NUM
admet-159	93	17	,	,	PUNCT
admet-159	93	18	or	or	CCONJ
admet-159	93	19	100	100	NUM
admet-159	93	20	μm	μm	NUM
admet-159	93	21	mncl2	mncl2	NOUN
admet-159	93	22	for	for	ADP
admet-159	93	23	24	24	NUM
admet-159	93	24	h.	h.	PROPN
admet-159	93	25	total	total	PROPN
admet-159	93	26	rna	rna	PROPN
admet-159	93	27	was	be	AUX
admet-159	93	28	isolated	isolate	VERB
admet-159	93	29	from	from	ADP
admet-159	93	30	the	the	DET
admet-159	93	31	cells	cell	NOUN
admet-159	93	32	using	use	VERB
admet-159	93	33	trizol	trizol	NOUN
admet-159	93	34	,	,	PUNCT
admet-159	93	35	following	follow	VERB
admet-159	93	36	the	the	DET
admet-159	93	37	manufacturer	manufacturer	NOUN
admet-159	93	38	’s	’s	PART
admet-159	93	39	directions	direction	NOUN
admet-159	93	40	.	.	PUNCT
admet-159	94	1	rna	rna	NOUN
admet-159	94	2	samples	sample	NOUN
admet-159	94	3	were	be	AUX
admet-159	94	4	reverseadmet	reverseadmet	ADJ
admet-159	94	5	&	&	CCONJ
admet-159	94	6	dmpk	dmpk	PROPN
admet-159	94	7	3(1	3(1	NUM
admet-159	94	8	)	)	PUNCT
admet-159	94	9	(	(	PUNCT
admet-159	94	10	2015	2015	NUM
admet-159	94	11	)	)	PUNCT
admet-159	94	12	15	15	NUM
admet-159	94	13	-	-	SYM
admet-159	94	14	33	33	NUM
admet-159	94	15	effects	effect	NOUN
admet-159	94	16	of	of	ADP
admet-159	94	17	manganese	manganese	ADJ
admet-159	94	18	exposure	exposure	NOUN
admet-159	94	19	on	on	ADP
admet-159	94	20	expression	expression	NOUN
admet-159	94	21	and	and	CCONJ
admet-159	94	22	transport	transport	NOUN
admet-159	94	23	of	of	ADP
admet-159	94	24	-synuclein	-synuclein	PROPN
admet-159	94	25	doi	doi	NOUN
admet-159	94	26	:	:	PUNCT
admet-159	94	27	10.5599	10.5599	NUM
admet-159	94	28	/	/	SYM
admet-159	94	29	admet.3.1.159	admet.3.1.159	NUM
admet-159	94	30	19	19	NUM
admet-159	94	31	transcribed	transcribe	VERB
admet-159	94	32	using	use	VERB
admet-159	94	33	the	the	DET
admet-159	94	34	biorad	biorad	ADJ
admet-159	94	35	iscript	iscript	PROPN
admet-159	94	36	cdna	cdna	PROPN
admet-159	94	37	synthesis	synthesis	NOUN
admet-159	94	38	kit	kit	NOUN
admet-159	94	39	(	(	PUNCT
admet-159	94	40	hercules	hercules	PROPN
admet-159	94	41	,	,	PUNCT
admet-159	94	42	ca	ca	NOUN
admet-159	94	43	)	)	PUNCT
admet-159	94	44	.	.	PUNCT
admet-159	95	1	the	the	DET
admet-159	95	2	itaq	itaq	PROPN
admet-159	95	3	universal	universal	ADJ
admet-159	95	4	sybr	sybr	PROPN
admet-159	95	5	green	green	ADJ
admet-159	95	6	supermix	supermix	PROPN
admet-159	95	7	(	(	PUNCT
admet-159	95	8	hercules	hercules	PROPN
admet-159	95	9	,	,	PUNCT
admet-159	95	10	ca	ca	NOUN
admet-159	95	11	)	)	PUNCT
admet-159	95	12	was	be	AUX
admet-159	95	13	used	use	VERB
admet-159	95	14	for	for	ADP
admet-159	95	15	qpcr	qpcr	ADJ
admet-159	95	16	analysis	analysis	NOUN
admet-159	95	17	.	.	PUNCT
admet-159	96	1	snca	snca	PROPN
admet-159	96	2	cdna	cdna	PROPN
admet-159	96	3	was	be	AUX
admet-159	96	4	amplified	amplify	VERB
admet-159	96	5	using	use	VERB
admet-159	96	6	the	the	DET
admet-159	96	7	following	follow	VERB
admet-159	96	8	nucleotide	nucleotide	ADJ
admet-159	96	9	sequences	sequence	NOUN
admet-159	96	10	:	:	PUNCT
admet-159	96	11	forward	forward	NOUN
admet-159	96	12	primer	primer	NOUN
admet-159	96	13	:	:	PUNCT
admet-159	96	14	5’-aga	5’-aga	PROPN
admet-159	96	15	tct	tct	PROPN
admet-159	96	16	gcc	gcc	NOUN
admet-159	96	17	cag	cag	PROPN
admet-159	96	18	gtg	gtg	PROPN
admet-159	96	19	ttc	ttc	PROPN
admet-159	96	20	ttcc-3	ttcc-3	PROPN
admet-159	96	21	’	'	PUNCT
admet-159	96	22	reverse	reverse	NOUN
admet-159	96	23	primer	primer	NOUN
admet-159	96	24	:	:	PUNCT
admet-159	96	25	5’-agg	5’-agg	NUM
admet-159	96	26	act	act	PROPN
admet-159	96	27	ccg	ccg	PROPN
admet-159	96	28	atc	atc	PROPN
admet-159	96	29	act	act	PROPN
admet-159	96	30	gct	gct	PROPN
admet-159	96	31	gatg-3	gatg-3	PROPN
admet-159	96	32	’	'	PUNCT
admet-159	96	33	the	the	DET
admet-159	96	34	primers	primer	NOUN
admet-159	96	35	were	be	AUX
admet-159	96	36	designed	design	VERB
admet-159	96	37	using	use	VERB
admet-159	96	38	the	the	DET
admet-159	96	39	primer	primer	NOUN
admet-159	96	40	express	express	VERB
admet-159	96	41	3.0	3.0	NUM
admet-159	96	42	software	software	NOUN
admet-159	96	43	.	.	PUNCT
admet-159	97	1	all	all	DET
admet-159	97	2	primers	primer	NOUN
admet-159	97	3	were	be	AUX
admet-159	97	4	obtained	obtain	VERB
admet-159	97	5	from	from	ADP
admet-159	97	6	integrated	integrate	VERB
admet-159	97	7	dna	dna	PROPN
admet-159	97	8	technologies	technology	NOUN
admet-159	97	9	(	(	PUNCT
admet-159	97	10	coralville	coralville	NOUN
admet-159	97	11	,	,	PUNCT
admet-159	97	12	ia	ia	PROPN
admet-159	97	13	)	)	PUNCT
admet-159	97	14	.	.	PUNCT
admet-159	98	1	the	the	DET
admet-159	98	2	amplification	amplification	NOUN
admet-159	98	3	was	be	AUX
admet-159	98	4	performed	perform	VERB
admet-159	98	5	in	in	ADP
admet-159	98	6	the	the	DET
admet-159	98	7	cfx	cfx	PROPN
admet-159	98	8	connecttm	connecttm	PROPN
admet-159	98	9	realtime	realtime	VERB
admet-159	98	10	pcr	pcr	ADJ
admet-159	98	11	detection	detection	NOUN
admet-159	98	12	system	system	NOUN
admet-159	98	13	(	(	PUNCT
admet-159	98	14	biorad	biorad	NOUN
admet-159	98	15	,	,	PUNCT
admet-159	98	16	hercules	hercule	NOUN
admet-159	98	17	,	,	PUNCT
admet-159	98	18	ca	ca	NOUN
admet-159	98	19	)	)	PUNCT
admet-159	98	20	.	.	PUNCT
admet-159	99	1	thioflavin	thioflavin	PROPN
admet-159	99	2	t	t	PROPN
admet-159	99	3	assay	assay	VERB
admet-159	99	4	recombinant	recombinant	ADJ
admet-159	99	5	human	human	ADJ
admet-159	99	6	a	a	PROPN
admet-159	99	7	-	-	PUNCT
admet-159	99	8	syn	syn	NOUN
admet-159	99	9	was	be	AUX
admet-159	99	10	produced	produce	VERB
admet-159	99	11	using	use	VERB
admet-159	99	12	the	the	DET
admet-159	99	13	methods	method	NOUN
admet-159	99	14	by	by	ADP
admet-159	99	15	zhang	zhang	PROPN
admet-159	99	16	et	et	PROPN
admet-159	99	17	al	al	PROPN
admet-159	99	18	.	.	PUNCT
admet-159	100	1	[	[	X
admet-159	100	2	49	49	NUM
admet-159	100	3	]	]	PUNCT
admet-159	100	4	.	.	PUNCT
admet-159	101	1	the	the	DET
admet-159	101	2	protein	protein	NOUN
admet-159	101	3	was	be	AUX
admet-159	101	4	dialyzed	dialyze	VERB
admet-159	101	5	in	in	ADP
admet-159	101	6	1x	1x	PROPN
admet-159	101	7	pbs	pbs	PROPN
admet-159	101	8	(	(	PUNCT
admet-159	101	9	137	137	NUM
admet-159	101	10	mm	mm	NOUN
admet-159	101	11	nacl	nacl	NOUN
admet-159	101	12	,	,	PUNCT
admet-159	101	13	2.7	2.7	NUM
admet-159	101	14	mm	mm	NOUN
admet-159	101	15	kcl	kcl	PROPN
admet-159	101	16	,	,	PUNCT
admet-159	101	17	10	10	NUM
admet-159	101	18	mm	mm	NOUN
admet-159	101	19	na2hpo4	na2hpo4	PROPN
admet-159	101	20	,	,	PUNCT
admet-159	101	21	and	and	CCONJ
admet-159	101	22	2	2	NUM
admet-159	101	23	mm	mm	NOUN
admet-159	101	24	kh2po4	kh2po4	NOUN
admet-159	101	25	,	,	PUNCT
admet-159	101	26	ph	ph	NOUN
admet-159	101	27	7.4	7.4	NUM
admet-159	101	28	)	)	PUNCT
admet-159	101	29	overnight	overnight	ADV
admet-159	101	30	prior	prior	ADV
admet-159	101	31	to	to	ADP
admet-159	101	32	use	use	NOUN
admet-159	101	33	in	in	ADP
admet-159	101	34	order	order	NOUN
admet-159	101	35	to	to	PART
admet-159	101	36	remove	remove	VERB
admet-159	101	37	excess	excess	ADJ
admet-159	101	38	salt	salt	NOUN
admet-159	101	39	.	.	PUNCT
admet-159	102	1	the	the	DET
admet-159	102	2	recombinant	recombinant	ADJ
admet-159	102	3	human	human	ADJ
admet-159	102	4	a	a	PROPN
admet-159	102	5	-	-	PUNCT
admet-159	102	6	syn	syn	NOUN
admet-159	102	7	protein	protein	NOUN
admet-159	102	8	(	(	PUNCT
admet-159	102	9	70	70	NUM
admet-159	102	10	μm	μm	NOUN
admet-159	102	11	)	)	PUNCT
admet-159	102	12	was	be	AUX
admet-159	102	13	incubated	incubate	VERB
admet-159	102	14	with	with	ADP
admet-159	102	15	100	100	NUM
admet-159	102	16	μm	μm	NUM
admet-159	102	17	mncl2	mncl2	PROPN
admet-159	102	18	,	,	PUNCT
admet-159	102	19	cucl2	cucl2	NOUN
admet-159	102	20	,	,	PUNCT
admet-159	102	21	or	or	CCONJ
admet-159	102	22	a	a	DET
admet-159	102	23	mixture	mixture	NOUN
admet-159	102	24	of	of	ADP
admet-159	102	25	mncl2	mncl2	PROPN
admet-159	102	26	and	and	CCONJ
admet-159	102	27	cucl2	cucl2	NOUN
admet-159	102	28	(	(	PUNCT
admet-159	102	29	each	each	PRON
admet-159	102	30	at	at	ADP
admet-159	102	31	100	100	NUM
admet-159	102	32	μm	μm	NUM
admet-159	102	33	)	)	PUNCT
admet-159	102	34	in	in	ADP
admet-159	102	35	a	a	DET
admet-159	102	36	200	200	NUM
admet-159	102	37	μl	μl	ADP
admet-159	102	38	solution	solution	NOUN
admet-159	102	39	of	of	ADP
admet-159	102	40	20	20	NUM
admet-159	102	41	mm	mm	NUM
admet-159	102	42	2-(n	2-(n	NUM
admet-159	102	43	-	-	PUNCT
admet-159	102	44	morpholino)ethanosulfonate	morpholino)ethanosulfonate	PROPN
admet-159	102	45	(	(	PUNCT
admet-159	102	46	mes	me	NOUN
admet-159	102	47	)	)	PUNCT
admet-159	102	48	buffer	buffer	NOUN
admet-159	102	49	containing	contain	VERB
admet-159	102	50	200	200	NUM
admet-159	102	51	μm	μm	NUM
admet-159	102	52	thioflavin	thioflavin	PROPN
admet-159	102	53	t	t	PROPN
admet-159	102	54	for	for	ADP
admet-159	102	55	72	72	NUM
admet-159	102	56	h	h	NOUN
admet-159	102	57	at	at	ADP
admet-159	102	58	37	37	NUM
admet-159	102	59	°	°	ADP
admet-159	102	60	c	c	NOUN
admet-159	102	61	under	under	ADP
admet-159	102	62	constant	constant	ADJ
admet-159	102	63	stirring	stirring	NOUN
admet-159	102	64	with	with	ADP
admet-159	102	65	a	a	DET
admet-159	102	66	teflon	teflon	NOUN
admet-159	102	67	ball	ball	NOUN
admet-159	102	68	.	.	PUNCT
admet-159	103	1	the	the	DET
admet-159	103	2	combination	combination	NOUN
admet-159	103	3	of	of	ADP
admet-159	103	4	mncl2	mncl2	PROPN
admet-159	103	5	and	and	CCONJ
admet-159	103	6	cucl2	cucl2	NOUN
admet-159	103	7	at	at	ADP
admet-159	103	8	100	100	NUM
admet-159	103	9	μm	μm	NOUN
admet-159	103	10	without	without	ADP
admet-159	103	11	a	a	PRON
admet-159	103	12	-	-	PUNCT
admet-159	103	13	syn	syn	NOUN
admet-159	103	14	are	be	AUX
admet-159	103	15	used	use	VERB
admet-159	103	16	as	as	ADP
admet-159	103	17	a	a	DET
admet-159	103	18	negative	negative	ADJ
admet-159	103	19	control	control	NOUN
admet-159	103	20	.	.	PUNCT
admet-159	104	1	fluorescence	fluorescence	NOUN
admet-159	104	2	readings	reading	NOUN
admet-159	104	3	were	be	AUX
admet-159	104	4	measured	measure	VERB
admet-159	104	5	with	with	ADP
admet-159	104	6	a	a	DET
admet-159	104	7	tecan	tecan	PROPN
admet-159	104	8	genios	genios	PROPN
admet-159	104	9	plate	plate	NOUN
admet-159	104	10	reader	reader	NOUN
admet-159	104	11	(	(	PUNCT
admet-159	104	12	san	san	PROPN
admet-159	104	13	jose	jose	PROPN
admet-159	104	14	,	,	PUNCT
admet-159	104	15	ca	ca	NOUN
admet-159	104	16	)	)	PUNCT
admet-159	104	17	every	every	DET
admet-159	104	18	15	15	NUM
admet-159	104	19	min	min	NOUN
admet-159	104	20	(	(	PUNCT
admet-159	104	21	excitation	excitation	NOUN
admet-159	104	22	:	:	PUNCT
admet-159	104	23	440	440	NUM
admet-159	104	24	nm	nm	NOUN
admet-159	104	25	;	;	PUNCT
admet-159	104	26	emission	emission	NOUN
admet-159	104	27	:	:	PUNCT
admet-159	104	28	480	480	NUM
admet-159	104	29	nm	nm	NOUN
admet-159	104	30	)	)	PUNCT
admet-159	104	31	.	.	PUNCT
admet-159	105	1	tecan	tecan	PROPN
admet-159	105	2	magellan	magellan	PROPN
admet-159	105	3	software	software	PROPN
admet-159	105	4	(	(	PUNCT
admet-159	105	5	san	san	PROPN
admet-159	105	6	jose	jose	PROPN
admet-159	105	7	,	,	PUNCT
admet-159	105	8	ca	ca	NOUN
admet-159	105	9	)	)	PUNCT
admet-159	105	10	was	be	AUX
admet-159	105	11	used	use	VERB
admet-159	105	12	for	for	ADP
admet-159	105	13	recording	record	VERB
admet-159	105	14	the	the	DET
admet-159	105	15	data	datum	NOUN
admet-159	105	16	.	.	PUNCT
admet-159	106	1	concentrations	concentration	NOUN
admet-159	106	2	of	of	ADP
admet-159	106	3	metal	metal	NOUN
admet-159	106	4	ions	ion	NOUN
admet-159	106	5	and	and	CCONJ
admet-159	106	6	a	a	X
admet-159	106	7	-	-	PUNCT
admet-159	106	8	syn	syn	NOUN
admet-159	106	9	were	be	AUX
admet-159	106	10	chosen	choose	VERB
admet-159	106	11	based	base	VERB
admet-159	106	12	on	on	ADP
admet-159	106	13	previous	previous	ADJ
admet-159	106	14	literature	literature	NOUN
admet-159	107	1	[	[	X
admet-159	107	2	38,39	38,39	NOUN
admet-159	107	3	]	]	X
admet-159	107	4	.	.	PUNCT
admet-159	108	1	cellular	cellular	ADJ
admet-159	108	2	uptake	uptake	NOUN
admet-159	108	3	of	of	ADP
admet-159	108	4	a	a	DET
admet-159	108	5	-	-	PUNCT
admet-159	108	6	syn	syn	NOUN
admet-159	108	7	and	and	CCONJ
admet-159	108	8	elisa	elisa	VERB
admet-159	108	9	quantification	quantification	NOUN
admet-159	108	10	primary	primary	ADJ
admet-159	108	11	rat	rat	NOUN
admet-159	108	12	plexus	plexus	NOUN
admet-159	108	13	cells	cell	NOUN
admet-159	108	14	were	be	AUX
admet-159	108	15	seeded	seed	VERB
admet-159	108	16	and	and	CCONJ
admet-159	108	17	cultured	cultured	ADJ
admet-159	108	18	as	as	SCONJ
admet-159	108	19	described	describe	VERB
admet-159	108	20	above	above	ADV
admet-159	108	21	.	.	PUNCT
admet-159	109	1	once	once	SCONJ
admet-159	109	2	the	the	DET
admet-159	109	3	cells	cell	NOUN
admet-159	109	4	reached	reach	VERB
admet-159	109	5	70	70	NUM
admet-159	109	6	-	-	SYM
admet-159	109	7	80	80	NUM
admet-159	109	8	%	%	NOUN
admet-159	109	9	confluence	confluence	NOUN
admet-159	109	10	,	,	PUNCT
admet-159	109	11	they	they	PRON
admet-159	109	12	were	be	AUX
admet-159	109	13	exposed	expose	VERB
admet-159	109	14	to	to	ADP
admet-159	109	15	25	25	NUM
admet-159	109	16	,	,	PUNCT
admet-159	109	17	50	50	NUM
admet-159	109	18	,	,	PUNCT
admet-159	109	19	or	or	CCONJ
admet-159	109	20	100	100	NUM
admet-159	109	21	μm	μm	NUM
admet-159	109	22	mncl2	mncl2	NOUN
admet-159	109	23	for	for	ADP
admet-159	109	24	24	24	NUM
admet-159	109	25	h.	h.	PROPN
admet-159	109	26	cells	cell	NOUN
admet-159	109	27	were	be	AUX
admet-159	109	28	then	then	ADV
admet-159	109	29	washed	wash	VERB
admet-159	109	30	with	with	ADP
admet-159	109	31	pbs	pbs	PROPN
admet-159	109	32	and	and	CCONJ
admet-159	109	33	incubated	incubate	VERB
admet-159	109	34	with	with	ADP
admet-159	109	35	0.5	0.5	NUM
admet-159	109	36	mg	mg	NOUN
admet-159	109	37	/	/	SYM
admet-159	109	38	ml	ml	X
admet-159	109	39	recombinant	recombinant	ADJ
admet-159	109	40	human	human	ADJ
admet-159	109	41	a	a	PROPN
admet-159	109	42	-	-	PUNCT
admet-159	109	43	syn	syn	NOUN
admet-159	109	44	for	for	ADP
admet-159	109	45	2	2	NUM
admet-159	109	46	h	h	NOUN
admet-159	109	47	in	in	ADP
admet-159	109	48	serum	serum	NOUN
admet-159	109	49	-	-	PUNCT
admet-159	109	50	free	free	ADJ
admet-159	109	51	dmem	dmem	ADJ
admet-159	109	52	medium	medium	NOUN
admet-159	109	53	.	.	PUNCT
admet-159	110	1	following	follow	VERB
admet-159	110	2	treatments	treatment	NOUN
admet-159	110	3	,	,	PUNCT
admet-159	110	4	cells	cell	NOUN
admet-159	110	5	were	be	AUX
admet-159	110	6	washed	wash	VERB
admet-159	110	7	and	and	CCONJ
admet-159	110	8	collected	collect	VERB
admet-159	110	9	.	.	PUNCT
admet-159	111	1	cell	cell	NOUN
admet-159	111	2	lysates	lysate	NOUN
admet-159	111	3	were	be	AUX
admet-159	111	4	analyzed	analyze	VERB
admet-159	111	5	for	for	ADP
admet-159	111	6	a	a	DET
admet-159	111	7	-	-	PUNCT
admet-159	111	8	syn	syn	NOUN
admet-159	111	9	content	content	NOUN
admet-159	111	10	via	via	ADP
admet-159	111	11	elisa	elisa	NOUN
admet-159	111	12	quantification	quantification	NOUN
admet-159	111	13	.	.	PUNCT
admet-159	112	1	protein	protein	NOUN
admet-159	112	2	lysates	lysate	NOUN
admet-159	112	3	were	be	AUX
admet-159	112	4	extracted	extract	VERB
admet-159	112	5	from	from	ADP
admet-159	112	6	cell	cell	NOUN
admet-159	112	7	samples	sample	NOUN
admet-159	112	8	in	in	ADP
admet-159	112	9	a	a	DET
admet-159	112	10	homogenization	homogenization	NOUN
admet-159	112	11	buffer	buffer	NOUN
admet-159	112	12	containing	contain	VERB
admet-159	112	13	20	20	NUM
admet-159	112	14	mm	mm	NUM
admet-159	112	15	tris	tris	NOUN
admet-159	112	16	,	,	PUNCT
admet-159	112	17	ph	ph	ADJ
admet-159	112	18	7.5	7.5	NUM
admet-159	112	19	,	,	PUNCT
admet-159	112	20	5	5	NUM
admet-159	112	21	mm	mm	NOUN
admet-159	112	22	egta	egta	NOUN
admet-159	112	23	,	,	PUNCT
admet-159	112	24	1	1	NUM
admet-159	112	25	%	%	NOUN
admet-159	112	26	triton	triton	PROPN
admet-159	112	27	x-100	x-100	PROPN
admet-159	112	28	,	,	PUNCT
admet-159	112	29	0.1	0.1	NUM
admet-159	112	30	%	%	NOUN
admet-159	112	31	sds	sds	NOUN
admet-159	112	32	,	,	PUNCT
admet-159	112	33	and	and	CCONJ
admet-159	112	34	protease	protease	NOUN
admet-159	112	35	inhibitor	inhibitor	NOUN
admet-159	112	36	cocktail	cocktail	NOUN
admet-159	112	37	(	(	PUNCT
admet-159	112	38	calbiochem	calbiochem	NOUN
admet-159	112	39	,	,	PUNCT
admet-159	112	40	san	san	PROPN
admet-159	112	41	diego	diego	PROPN
admet-159	112	42	,	,	PUNCT
admet-159	112	43	ca	ca	NOUN
admet-159	112	44	)	)	PUNCT
admet-159	112	45	.	.	PUNCT
admet-159	113	1	samples	sample	NOUN
admet-159	113	2	were	be	AUX
admet-159	113	3	sonicated	sonicate	VERB
admet-159	113	4	,	,	PUNCT
admet-159	113	5	centrifuged	centrifuge	VERB
admet-159	113	6	,	,	PUNCT
admet-159	113	7	and	and	CCONJ
admet-159	113	8	quantified	quantify	VERB
admet-159	113	9	for	for	ADP
admet-159	113	10	protein	protein	NOUN
admet-159	113	11	concentration	concentration	NOUN
admet-159	113	12	using	use	VERB
admet-159	113	13	the	the	DET
admet-159	113	14	bradford	bradford	NOUN
admet-159	113	15	protein	protein	NOUN
admet-159	113	16	assay	assay	VERB
admet-159	113	17	.	.	PUNCT
admet-159	114	1	medium	medium	ADJ
admet-159	114	2	and	and	CCONJ
admet-159	114	3	cell	cell	NOUN
admet-159	114	4	samples	sample	NOUN
admet-159	114	5	were	be	AUX
admet-159	114	6	diluted	dilute	VERB
admet-159	114	7	25	25	NUM
admet-159	114	8	-	-	NOUN
admet-159	114	9	fold	fold	ADJ
admet-159	114	10	in	in	ADP
admet-159	114	11	diluent	diluent	NOUN
admet-159	114	12	buffer	buffer	NOUN
admet-159	114	13	included	include	VERB
admet-159	114	14	in	in	ADP
admet-159	114	15	the	the	DET
admet-159	114	16	human	human	ADJ
admet-159	114	17	a	a	DET
admet-159	114	18	-	-	PUNCT
admet-159	114	19	synuclein	synuclein	NOUN
admet-159	114	20	elisa	elisa	PROPN
admet-159	114	21	kit	kit	PROPN
admet-159	114	22	(	(	PUNCT
admet-159	114	23	product	product	NOUN
admet-159	114	24	khb0061	khb0061	PROPN
admet-159	114	25	,	,	PUNCT
admet-159	114	26	invitrogen	invitrogen	PROPN
admet-159	114	27	,	,	PUNCT
admet-159	114	28	frederick	frederick	PROPN
admet-159	114	29	,	,	PUNCT
admet-159	114	30	md	md	PROPN
admet-159	114	31	)	)	PUNCT
admet-159	114	32	in	in	ADP
admet-159	114	33	accordance	accordance	NOUN
admet-159	114	34	with	with	ADP
admet-159	114	35	the	the	DET
admet-159	114	36	product	product	NOUN
admet-159	114	37	’s	’s	PART
admet-159	114	38	protocol	protocol	NOUN
admet-159	114	39	.	.	PUNCT
admet-159	115	1	samples	sample	NOUN
admet-159	115	2	were	be	AUX
admet-159	115	3	measured	measure	VERB
admet-159	115	4	for	for	ADP
admet-159	115	5	fluorescence	fluorescence	NOUN
admet-159	115	6	at	at	ADP
admet-159	115	7	450	450	NUM
admet-159	115	8	nm	nm	NOUN
admet-159	115	9	with	with	ADP
admet-159	115	10	an	an	DET
admet-159	115	11	m2e	m2e	NOUN
admet-159	115	12	plate	plate	NOUN
admet-159	115	13	reader	reader	NOUN
admet-159	115	14	(	(	PUNCT
admet-159	115	15	molecular	molecular	ADJ
admet-159	115	16	devices	device	NOUN
admet-159	115	17	,	,	PUNCT
admet-159	115	18	sunnyvale	sunnyvale	PROPN
admet-159	115	19	,	,	PUNCT
admet-159	115	20	ca	ca	NOUN
admet-159	115	21	)	)	PUNCT
admet-159	115	22	and	and	CCONJ
admet-159	115	23	the	the	DET
admet-159	115	24	softmax	softmax	ADJ
admet-159	115	25	pro	pro	ADJ
admet-159	115	26	analysis	analysis	NOUN
admet-159	115	27	software	software	NOUN
admet-159	115	28	(	(	PUNCT
admet-159	115	29	version	version	NOUN
admet-159	115	30	5.4	5.4	NUM
admet-159	115	31	,	,	PUNCT
admet-159	115	32	molecular	molecular	ADJ
admet-159	115	33	devices	device	NOUN
admet-159	115	34	,	,	PUNCT
admet-159	115	35	sunnyvale	sunnyvale	PROPN
admet-159	115	36	,	,	PUNCT
admet-159	115	37	ca	ca	NOUN
admet-159	115	38	)	)	PUNCT
admet-159	115	39	within	within	ADP
admet-159	115	40	2	2	NUM
admet-159	115	41	h	h	NOUN
admet-159	115	42	of	of	ADP
admet-159	115	43	the	the	DET
admet-159	115	44	addition	addition	NOUN
admet-159	115	45	of	of	ADP
admet-159	115	46	the	the	DET
admet-159	115	47	stop	stop	NOUN
admet-159	115	48	solution	solution	NOUN
admet-159	115	49	.	.	PUNCT
admet-159	116	1	transport	transport	NOUN
admet-159	116	2	of	of	ADP
admet-159	116	3	a	a	DET
admet-159	116	4	-	-	PUNCT
admet-159	116	5	syn	syn	NOUN
admet-159	116	6	across	across	ADP
admet-159	116	7	bcsfb	bcsfb	PROPN
admet-159	116	8	monolayer	monolayer	NOUN
admet-159	116	9	in	in	ADP
admet-159	116	10	two	two	NUM
admet-159	116	11	-	-	PUNCT
admet-159	116	12	chamber	chamber	NOUN
admet-159	116	13	transwell	transwell	NOUN
admet-159	116	14	system	system	NOUN
admet-159	116	15	please	please	INTJ
admet-159	116	16	refer	refer	VERB
admet-159	116	17	to	to	ADP
admet-159	116	18	fu	fu	PROPN
admet-159	116	19	et	et	PROPN
admet-159	116	20	al	al	PROPN
admet-159	116	21	.	.	PUNCT
admet-159	117	1	[	[	X
admet-159	117	2	29	29	NUM
admet-159	117	3	]	]	PUNCT
admet-159	117	4	for	for	ADP
admet-159	117	5	a	a	DET
admet-159	117	6	more	more	ADV
admet-159	117	7	detailed	detailed	ADJ
admet-159	117	8	description	description	NOUN
admet-159	117	9	of	of	ADP
admet-159	117	10	this	this	DET
admet-159	117	11	procedure	procedure	NOUN
admet-159	117	12	.	.	PUNCT
admet-159	118	1	rat	rat	NOUN
admet-159	118	2	choroid	choroid	PROPN
admet-159	118	3	plexus	plexus	NOUN
admet-159	118	4	primary	primary	ADJ
admet-159	118	5	cells	cell	NOUN
admet-159	118	6	,	,	PUNCT
admet-159	118	7	obtained	obtain	VERB
admet-159	118	8	as	as	ADP
admet-159	118	9	previously	previously	ADV
admet-159	118	10	described	describe	VERB
admet-159	118	11	were	be	AUX
admet-159	118	12	seeded	seed	VERB
admet-159	118	13	on	on	ADP
admet-159	118	14	collagen	collagen	NOUN
admet-159	118	15	-	-	PUNCT
admet-159	118	16	coated	coat	VERB
admet-159	118	17	laminin	laminin	NOUN
admet-159	118	18	membranes	membrane	NOUN
admet-159	118	19	in	in	ADP
admet-159	118	20	the	the	DET
admet-159	118	21	inner	inner	ADJ
admet-159	118	22	chamber	chamber	NOUN
admet-159	118	23	of	of	ADP
admet-159	118	24	a	a	DET
admet-159	118	25	two	two	NUM
admet-159	118	26	-	-	PUNCT
admet-159	118	27	chamber	chamber	NOUN
admet-159	118	28	transwell	transwell	NOUN
admet-159	118	29	system	system	NOUN
admet-159	118	30	.	.	PUNCT
admet-159	119	1	figure	figure	NOUN
admet-159	119	2	s1	s1	PROPN
admet-159	119	3	illustrates	illustrate	VERB
admet-159	119	4	the	the	DET
admet-159	119	5	concept	concept	NOUN
admet-159	119	6	of	of	ADP
admet-159	119	7	this	this	DET
admet-159	119	8	transport	transport	NOUN
admet-159	119	9	system	system	NOUN
admet-159	119	10	.	.	PUNCT
admet-159	120	1	a	a	DET
admet-159	120	2	1.0	1.0	NUM
admet-159	120	3	ml	ml	NOUN
admet-159	120	4	aliquot	aliquot	NOUN
admet-159	120	5	of	of	ADP
admet-159	120	6	growth	growth	NOUN
admet-159	120	7	dmem	dmem	VERB
admet-159	120	8	medium	medium	NOUN
admet-159	120	9	was	be	AUX
admet-159	120	10	added	add	VERB
admet-159	120	11	to	to	ADP
admet-159	120	12	the	the	DET
admet-159	120	13	inner	inner	ADJ
admet-159	120	14	chamber	chamber	NOUN
admet-159	120	15	.	.	PUNCT
admet-159	121	1	the	the	DET
admet-159	121	2	inner	inner	ADJ
admet-159	121	3	chamber	chamber	NOUN
admet-159	121	4	was	be	AUX
admet-159	121	5	then	then	ADV
admet-159	121	6	immersed	immerse	VERB
admet-159	121	7	in	in	ADP
admet-159	121	8	1.0	1.0	NUM
admet-159	121	9	ml	ml	NOUN
admet-159	121	10	of	of	ADP
admet-159	121	11	medium	medium	NOUN
admet-159	121	12	in	in	ADP
admet-159	121	13	the	the	DET
admet-159	121	14	outer	outer	ADJ
admet-159	121	15	chamber	chamber	NOUN
admet-159	121	16	.	.	PUNCT
admet-159	122	1	cells	cell	NOUN
admet-159	122	2	were	be	AUX
admet-159	122	3	cultured	cultured	ADJ
admet-159	122	4	in	in	ADP
admet-159	122	5	the	the	DET
admet-159	122	6	medium	medium	NOUN
admet-159	122	7	for	for	ADP
admet-159	122	8	7	7	NUM
admet-159	122	9	-	-	SYM
admet-159	122	10	10	10	NUM
admet-159	122	11	days	day	NOUN
admet-159	122	12	to	to	ADP
admet-159	122	13	the	the	DET
admet-159	122	14	confluence	confluence	NOUN
admet-159	122	15	.	.	PUNCT
admet-159	123	1	wells	well	NOUN
admet-159	123	2	were	be	AUX
admet-159	123	3	then	then	ADV
admet-159	123	4	divided	divide	VERB
admet-159	123	5	into	into	ADP
admet-159	123	6	2	2	NUM
admet-159	123	7	main	main	ADJ
admet-159	123	8	sets	set	NOUN
admet-159	123	9	,	,	PUNCT
admet-159	123	10	i.e.	i.e.	X
admet-159	123	11	,	,	PUNCT
admet-159	123	12	one	one	PRON
admet-159	123	13	set	set	NOUN
admet-159	123	14	for	for	ADP
admet-159	123	15	the	the	DET
admet-159	123	16	influx	influx	NOUN
admet-159	123	17	studies	study	NOUN
admet-159	123	18	and	and	CCONJ
admet-159	123	19	the	the	DET
admet-159	123	20	bates	bate	NOUN
admet-159	123	21	et	et	PROPN
admet-159	123	22	al	al	PROPN
admet-159	123	23	.	.	PROPN
admet-159	123	24	admet	admet	PROPN
admet-159	123	25	&	&	CCONJ
admet-159	123	26	dmpk	dmpk	PROPN
admet-159	123	27	3(1	3(1	NUM
admet-159	123	28	)	)	PUNCT
admet-159	123	29	(	(	PUNCT
admet-159	123	30	2015	2015	NUM
admet-159	123	31	)	)	PUNCT
admet-159	123	32	15	15	NUM
admet-159	123	33	-	-	SYM
admet-159	123	34	33	33	NUM
admet-159	123	35	20	20	NUM
admet-159	123	36	other	other	ADJ
admet-159	123	37	for	for	ADP
admet-159	123	38	the	the	DET
admet-159	123	39	efflux	efflux	NOUN
admet-159	123	40	studies	study	NOUN
admet-159	123	41	.	.	PUNCT
admet-159	124	1	each	each	DET
admet-159	124	2	set	set	NOUN
admet-159	124	3	was	be	AUX
admet-159	124	4	further	far	ADV
admet-159	124	5	divided	divide	VERB
admet-159	124	6	into	into	ADP
admet-159	124	7	3	3	NUM
admet-159	124	8	time	time	NOUN
admet-159	124	9	points	point	NOUN
admet-159	124	10	:	:	PUNCT
admet-159	124	11	6	6	NUM
admet-159	124	12	,	,	PUNCT
admet-159	124	13	12	12	NUM
admet-159	124	14	,	,	PUNCT
admet-159	124	15	and	and	CCONJ
admet-159	124	16	24	24	NUM
admet-159	124	17	h.	h.	NOUN
admet-159	124	18	each	each	DET
admet-159	124	19	time	time	NOUN
admet-159	124	20	point	point	NOUN
admet-159	124	21	was	be	AUX
admet-159	124	22	comprised	comprise	VERB
admet-159	124	23	of	of	ADP
admet-159	124	24	a	a	DET
admet-159	124	25	control	control	NOUN
admet-159	124	26	(	(	PUNCT
admet-159	124	27	no	no	DET
admet-159	124	28	treatment	treatment	NOUN
admet-159	124	29	)	)	PUNCT
admet-159	124	30	and	and	CCONJ
admet-159	124	31	a	a	DET
admet-159	124	32	mn	mn	PROPN
admet-159	124	33	-	-	PUNCT
admet-159	124	34	treated	treat	VERB
admet-159	124	35	group	group	NOUN
admet-159	124	36	.	.	PUNCT
admet-159	125	1	transepithelial	transepithelial	ADJ
admet-159	125	2	electrical	electrical	ADJ
admet-159	125	3	resistance	resistance	NOUN
admet-159	125	4	(	(	PUNCT
admet-159	125	5	teer	teer	PROPN
admet-159	125	6	)	)	PUNCT
admet-159	125	7	,	,	PUNCT
admet-159	125	8	an	an	DET
admet-159	125	9	indicator	indicator	NOUN
admet-159	125	10	of	of	ADP
admet-159	125	11	barrier	barrier	NOUN
admet-159	125	12	tightness	tightness	NOUN
admet-159	125	13	,	,	PUNCT
admet-159	125	14	was	be	AUX
admet-159	125	15	used	use	VERB
admet-159	125	16	to	to	PART
admet-159	125	17	monitor	monitor	VERB
admet-159	125	18	the	the	DET
admet-159	125	19	development	development	NOUN
admet-159	125	20	and	and	CCONJ
admet-159	125	21	the	the	DET
admet-159	125	22	tightness	tightness	NOUN
admet-159	125	23	of	of	ADP
admet-159	125	24	the	the	DET
admet-159	125	25	barrier	barrier	NOUN
admet-159	125	26	monolayer	monolayer	NOUN
admet-159	125	27	on	on	ADP
admet-159	125	28	the	the	DET
admet-159	125	29	laminin	laminin	NOUN
admet-159	125	30	membrane	membrane	NOUN
admet-159	125	31	.	.	PUNCT
admet-159	126	1	teer	teer	NOUN
admet-159	126	2	readings	reading	NOUN
admet-159	126	3	were	be	AUX
admet-159	126	4	taken	take	VERB
admet-159	126	5	every	every	DET
admet-159	126	6	2	2	NUM
admet-159	126	7	days	day	NOUN
admet-159	126	8	until	until	SCONJ
admet-159	126	9	the	the	DET
admet-159	126	10	resistance	resistance	NOUN
admet-159	126	11	reached	reach	VERB
admet-159	126	12	50	50	NUM
admet-159	126	13	-	-	SYM
admet-159	126	14	60	60	NUM
admet-159	126	15	ω	ω	NUM
admet-159	126	16	cm	cm	NOUN
admet-159	126	17	2	2	NUM
admet-159	126	18	,	,	PUNCT
admet-159	126	19	which	which	PRON
admet-159	126	20	confirms	confirm	VERB
admet-159	126	21	the	the	DET
admet-159	126	22	presence	presence	NOUN
admet-159	126	23	of	of	ADP
admet-159	126	24	tight	tight	ADJ
admet-159	126	25	junctions	junction	NOUN
admet-159	126	26	throughout	throughout	ADP
admet-159	126	27	the	the	DET
admet-159	126	28	barrier	barrier	NOUN
admet-159	126	29	[	[	X
admet-159	126	30	27,29,46	27,29,46	NUM
admet-159	126	31	]	]	X
admet-159	126	32	.	.	PUNCT
admet-159	127	1	once	once	SCONJ
admet-159	127	2	the	the	DET
admet-159	127	3	cell	cell	NOUN
admet-159	127	4	monolayer	monolayer	NOUN
admet-159	127	5	was	be	AUX
admet-159	127	6	confluent	confluent	ADJ
admet-159	127	7	and	and	CCONJ
admet-159	127	8	completely	completely	ADV
admet-159	127	9	developed	develop	VERB
admet-159	127	10	,	,	PUNCT
admet-159	127	11	cells	cell	NOUN
admet-159	127	12	designated	designate	VERB
admet-159	127	13	for	for	ADP
admet-159	127	14	mn	mn	PROPN
admet-159	127	15	treatment	treatment	NOUN
admet-159	127	16	were	be	AUX
admet-159	127	17	treated	treat	VERB
admet-159	127	18	with	with	ADP
admet-159	127	19	100	100	NUM
admet-159	127	20	μm	μm	NUM
admet-159	127	21	mncl2	mncl2	NOUN
admet-159	127	22	for	for	ADP
admet-159	127	23	24	24	NUM
admet-159	127	24	h.	h.	PROPN
admet-159	127	25	cells	cell	NOUN
admet-159	127	26	were	be	AUX
admet-159	127	27	incubated	incubate	VERB
admet-159	127	28	with	with	ADP
admet-159	127	29	1.0	1.0	NUM
admet-159	127	30	mg	mg	NOUN
admet-159	127	31	/	/	SYM
admet-159	127	32	ml	ml	NOUN
admet-159	127	33	a	a	PROPN
admet-159	127	34	-	-	PUNCT
admet-159	127	35	syn	syn	NOUN
admet-159	127	36	dissolved	dissolve	VERB
admet-159	127	37	in	in	ADP
admet-159	127	38	serum	serum	NOUN
admet-159	127	39	-	-	PUNCT
admet-159	127	40	free	free	ADJ
admet-159	127	41	dmem	dmem	ADJ
admet-159	127	42	medium	medium	NOUN
admet-159	127	43	.	.	PUNCT
admet-159	128	1	a	a	X
admet-159	128	2	-	-	PUNCT
admet-159	128	3	syn	syn	PROPN
admet-159	128	4	was	be	AUX
admet-159	128	5	added	add	VERB
admet-159	128	6	to	to	ADP
admet-159	128	7	the	the	DET
admet-159	128	8	outer	outer	ADJ
admet-159	128	9	chamber	chamber	NOUN
admet-159	128	10	for	for	ADP
admet-159	128	11	the	the	DET
admet-159	128	12	“	"	PUNCT
admet-159	128	13	influx	influx	NOUN
admet-159	128	14	”	"	PUNCT
admet-159	128	15	study	study	NOUN
admet-159	128	16	;	;	PUNCT
admet-159	128	17	for	for	ADP
admet-159	128	18	the	the	DET
admet-159	128	19	“	"	PUNCT
admet-159	128	20	efflux	efflux	NOUN
admet-159	128	21	”	"	PUNCT
admet-159	128	22	study	study	NOUN
admet-159	128	23	,	,	PUNCT
admet-159	128	24	a	a	PRON
admet-159	128	25	-	-	PUNCT
admet-159	128	26	syn	syn	NOUN
admet-159	128	27	was	be	AUX
admet-159	128	28	added	add	VERB
admet-159	128	29	to	to	ADP
admet-159	128	30	the	the	DET
admet-159	128	31	inner	inner	ADJ
admet-159	128	32	chamber	chamber	NOUN
admet-159	128	33	only	only	ADV
admet-159	128	34	.	.	PUNCT
admet-159	129	1	a	a	DET
admet-159	129	2	20	20	NUM
admet-159	129	3	-	-	PUNCT
admet-159	129	4	μl	μl	NOUN
admet-159	129	5	aliquot	aliquot	NOUN
admet-159	129	6	of	of	ADP
admet-159	129	7	both	both	DET
admet-159	129	8	chambers	chamber	NOUN
admet-159	129	9	and	and	CCONJ
admet-159	129	10	cells	cell	NOUN
admet-159	129	11	was	be	AUX
admet-159	129	12	collected	collect	VERB
admet-159	129	13	at	at	ADP
admet-159	129	14	each	each	DET
admet-159	129	15	time	time	NOUN
admet-159	129	16	point	point	NOUN
admet-159	129	17	and	and	CCONJ
admet-159	129	18	immediately	immediately	ADV
admet-159	129	19	frozen	freeze	VERB
admet-159	129	20	at	at	ADP
admet-159	129	21	-80	-80	NOUN
admet-159	129	22	°	°	ADP
admet-159	129	23	c	c	NOUN
admet-159	129	24	until	until	ADP
admet-159	129	25	being	be	AUX
admet-159	129	26	thawed	thaw	VERB
admet-159	129	27	for	for	ADP
admet-159	129	28	elisa	elisa	NOUN
admet-159	129	29	quantification	quantification	NOUN
admet-159	129	30	.	.	PUNCT
admet-159	130	1	statistical	statistical	ADJ
admet-159	130	2	analysis	analysis	NOUN
admet-159	130	3	confocal	confocal	ADJ
admet-159	130	4	quantification	quantification	NOUN
admet-159	130	5	and	and	CCONJ
admet-159	130	6	the	the	DET
admet-159	130	7	transwell	transwell	NOUN
admet-159	130	8	chamber	chamber	NOUN
admet-159	130	9	studies	study	NOUN
admet-159	130	10	were	be	AUX
admet-159	130	11	analyzed	analyze	VERB
admet-159	130	12	using	use	VERB
admet-159	130	13	one	one	NUM
admet-159	130	14	-	-	PUNCT
admet-159	130	15	way	way	NOUN
admet-159	130	16	or	or	CCONJ
admet-159	130	17	twoanova	twoanova	VERB
admet-159	130	18	with	with	ADP
admet-159	130	19	tukey	tukey	PROPN
admet-159	130	20	’s	’s	PART
admet-159	130	21	post	post	ADJ
admet-159	130	22	-	-	ADJ
admet-159	130	23	hoc	hoc	ADJ
admet-159	130	24	test	test	NOUN
admet-159	130	25	as	as	ADP
admet-159	130	26	necessary	necessary	ADJ
admet-159	130	27	.	.	PUNCT
admet-159	131	1	qpcr	qpcr	ADJ
admet-159	131	2	data	datum	NOUN
admet-159	131	3	were	be	AUX
admet-159	131	4	analyzed	analyze	VERB
admet-159	131	5	with	with	ADP
admet-159	131	6	one	one	NUM
admet-159	131	7	-	-	PUNCT
admet-159	131	8	way	way	NOUN
admet-159	131	9	anova	anova	PROPN
admet-159	131	10	and	and	CCONJ
admet-159	131	11	the	the	DET
admet-159	131	12	dunnett	dunnett	PROPN
admet-159	131	13	’s	’s	PART
admet-159	131	14	post	post	ADJ
admet-159	131	15	-	-	ADJ
admet-159	131	16	hoc	hoc	ADJ
admet-159	131	17	test	test	NOUN
admet-159	131	18	.	.	PUNCT
admet-159	132	1	the	the	DET
admet-159	132	2	a	a	PROPN
admet-159	132	3	-	-	PUNCT
admet-159	132	4	syn	syn	NOUN
admet-159	132	5	uptake	uptake	ADJ
admet-159	132	6	studies	study	NOUN
admet-159	132	7	quantified	quantify	VERB
admet-159	132	8	with	with	ADP
admet-159	132	9	elisa	elisa	PROPN
admet-159	132	10	were	be	AUX
admet-159	132	11	analyzed	analyze	VERB
admet-159	132	12	with	with	ADP
admet-159	132	13	one	one	NUM
admet-159	132	14	-	-	PUNCT
admet-159	132	15	way	way	NOUN
admet-159	132	16	anova	anova	PROPN
admet-159	132	17	and	and	CCONJ
admet-159	132	18	the	the	DET
admet-159	132	19	tukey	tukey	NOUN
admet-159	132	20	’s	’s	PART
admet-159	132	21	post	post	ADJ
admet-159	132	22	-	-	ADJ
admet-159	132	23	hoc	hoc	ADJ
admet-159	132	24	test	test	NOUN
admet-159	132	25	.	.	PUNCT
admet-159	133	1	any	any	DET
admet-159	133	2	p	p	PROPN
admet-159	133	3	values	value	NOUN
admet-159	133	4	equal	equal	ADJ
admet-159	133	5	to	to	ADP
admet-159	133	6	or	or	CCONJ
admet-159	133	7	less	less	ADJ
admet-159	133	8	than	than	ADP
admet-159	133	9	0.05	0.05	NUM
admet-159	133	10	were	be	AUX
admet-159	133	11	considered	consider	VERB
admet-159	133	12	statistically	statistically	ADV
admet-159	133	13	significant	significant	ADJ
admet-159	133	14	.	.	PUNCT
admet-159	134	1	results	result	VERB
admet-159	134	2	expression	expression	NOUN
admet-159	134	3	of	of	ADP
admet-159	134	4	a	a	DET
admet-159	134	5	-	-	PUNCT
admet-159	134	6	syn	syn	NOUN
admet-159	134	7	in	in	ADP
admet-159	134	8	the	the	DET
admet-159	134	9	choroidal	choroidal	ADJ
admet-159	134	10	epithelia	epithelium	NOUN
admet-159	134	11	and	and	CCONJ
admet-159	134	12	effects	effect	NOUN
admet-159	134	13	of	of	ADP
admet-159	134	14	mn	mn	PROPN
admet-159	134	15	exposure	exposure	NOUN
admet-159	134	16	data	datum	NOUN
admet-159	134	17	from	from	ADP
admet-159	134	18	freshly	freshly	ADV
admet-159	134	19	isolated	isolate	VERB
admet-159	134	20	choroid	choroid	NOUN
admet-159	134	21	plexus	plexus	NOUN
admet-159	134	22	tissue	tissue	NOUN
admet-159	134	23	(	(	PUNCT
admet-159	134	24	fig	fig	NOUN
admet-159	134	25	.	.	PUNCT
admet-159	135	1	1a	1a	NOUN
admet-159	135	2	)	)	PUNCT
admet-159	136	1	and	and	CCONJ
admet-159	136	2	choroidal	choroidal	ADJ
admet-159	136	3	epithelial	epithelial	ADJ
admet-159	136	4	z310	z310	PROPN
admet-159	136	5	cells	cell	NOUN
admet-159	136	6	(	(	PUNCT
admet-159	136	7	fig	fig	NOUN
admet-159	136	8	.	.	PUNCT
admet-159	136	9	1b	1b	NUM
admet-159	136	10	)	)	PUNCT
admet-159	136	11	showed	show	VERB
admet-159	136	12	that	that	SCONJ
admet-159	136	13	the	the	DET
admet-159	136	14	choroid	choroid	NOUN
admet-159	136	15	plexus	plexus	NOUN
admet-159	136	16	cells	cell	NOUN
admet-159	136	17	expressed	express	VERB
admet-159	136	18	strong	strong	ADJ
admet-159	136	19	fluorescent	fluorescent	ADJ
admet-159	136	20	signals	signal	NOUN
admet-159	136	21	representing	represent	VERB
admet-159	136	22	a	a	DET
admet-159	136	23	-	-	PUNCT
admet-159	136	24	syn	syn	NOUN
admet-159	136	25	;	;	PUNCT
admet-159	136	26	furthermore	furthermore	ADV
admet-159	136	27	,	,	PUNCT
admet-159	136	28	the	the	DET
admet-159	136	29	fluorescent	fluorescent	ADJ
admet-159	136	30	signal	signal	NOUN
admet-159	136	31	was	be	AUX
admet-159	136	32	present	present	ADJ
admet-159	136	33	primarily	primarily	ADV
admet-159	136	34	in	in	ADP
admet-159	136	35	the	the	DET
admet-159	136	36	cytoplasm	cytoplasm	NOUN
admet-159	136	37	of	of	ADP
admet-159	136	38	these	these	DET
admet-159	136	39	cells	cell	NOUN
admet-159	136	40	.	.	PUNCT
admet-159	137	1	this	this	DET
admet-159	137	2	cytoplasmic	cytoplasmic	ADJ
admet-159	137	3	expression	expression	NOUN
admet-159	137	4	of	of	ADP
admet-159	137	5	a	a	PRON
admet-159	137	6	-	-	PUNCT
admet-159	137	7	syn	syn	NOUN
admet-159	137	8	is	be	AUX
admet-159	137	9	consistent	consistent	ADJ
admet-159	137	10	with	with	ADP
admet-159	137	11	the	the	DET
admet-159	137	12	localization	localization	NOUN
admet-159	137	13	of	of	ADP
admet-159	137	14	a	a	DET
admet-159	137	15	-	-	PUNCT
admet-159	137	16	syn	syn	NOUN
admet-159	137	17	in	in	ADP
admet-159	137	18	other	other	ADJ
admet-159	137	19	cell	cell	NOUN
admet-159	137	20	types	type	NOUN
admet-159	137	21	described	describe	VERB
admet-159	137	22	previously	previously	ADV
admet-159	137	23	in	in	ADP
admet-159	137	24	the	the	DET
admet-159	137	25	literature	literature	NOUN
admet-159	137	26	[	[	X
admet-159	137	27	2,50	2,50	X
admet-159	137	28	]	]	X
admet-159	137	29	.	.	PUNCT
admet-159	138	1	our	our	PRON
admet-159	138	2	data	datum	NOUN
admet-159	138	3	clearly	clearly	ADV
admet-159	138	4	show	show	VERB
admet-159	138	5	that	that	SCONJ
admet-159	138	6	choroidal	choroidal	ADJ
admet-159	138	7	epithelial	epithelial	ADJ
admet-159	138	8	cells	cell	NOUN
admet-159	138	9	possess	possess	VERB
admet-159	138	10	the	the	DET
admet-159	138	11	ability	ability	NOUN
admet-159	138	12	to	to	PART
admet-159	138	13	express	express	VERB
admet-159	138	14	endogenous	endogenous	ADJ
admet-159	138	15	a	a	PRON
admet-159	138	16	-	-	PUNCT
admet-159	138	17	syn	syn	NOUN
admet-159	138	18	.	.	PROPN
admet-159	139	1	following	follow	VERB
admet-159	139	2	incubation	incubation	NOUN
admet-159	139	3	of	of	ADP
admet-159	139	4	z310	z310	PROPN
admet-159	139	5	cells	cell	NOUN
admet-159	139	6	with	with	ADP
admet-159	139	7	100	100	NUM
admet-159	139	8	μm	μm	NUM
admet-159	139	9	mncl2	mncl2	NOUN
admet-159	139	10	for	for	ADP
admet-159	139	11	48	48	NUM
admet-159	139	12	h	h	NOUN
admet-159	139	13	,	,	PUNCT
admet-159	139	14	some	some	DET
admet-159	139	15	small	small	ADJ
admet-159	139	16	,	,	PUNCT
admet-159	139	17	yet	yet	CCONJ
admet-159	139	18	bright	bright	ADJ
admet-159	139	19	green	green	ADJ
admet-159	139	20	dots	dot	NOUN
admet-159	139	21	appeared	appear	VERB
admet-159	139	22	to	to	PART
admet-159	139	23	form	form	VERB
admet-159	139	24	in	in	ADP
admet-159	139	25	the	the	DET
admet-159	139	26	cytoplasm	cytoplasm	NOUN
admet-159	139	27	(	(	PUNCT
admet-159	139	28	fig	fig	NOUN
admet-159	139	29	.	.	PUNCT
admet-159	140	1	2a	2a	NUM
admet-159	140	2	)	)	PUNCT
admet-159	140	3	.	.	PUNCT
admet-159	141	1	control	control	NOUN
admet-159	141	2	z310	z310	PROPN
admet-159	141	3	cells	cell	NOUN
admet-159	141	4	did	do	AUX
admet-159	141	5	not	not	PART
admet-159	141	6	display	display	VERB
admet-159	141	7	these	these	DET
admet-159	141	8	dots	dot	NOUN
admet-159	141	9	.	.	PUNCT
admet-159	142	1	however	however	ADV
admet-159	142	2	,	,	PUNCT
admet-159	142	3	quantitation	quantitation	NOUN
admet-159	142	4	of	of	ADP
admet-159	142	5	the	the	DET
admet-159	142	6	intensity	intensity	NOUN
admet-159	142	7	of	of	ADP
admet-159	142	8	a	a	DET
admet-159	142	9	-	-	PUNCT
admet-159	142	10	syn	syn	NOUN
admet-159	142	11	signals	signal	NOUN
admet-159	142	12	in	in	ADP
admet-159	142	13	these	these	DET
admet-159	142	14	cells	cell	NOUN
admet-159	142	15	did	do	AUX
admet-159	142	16	not	not	PART
admet-159	142	17	reveal	reveal	VERB
admet-159	142	18	a	a	DET
admet-159	142	19	significant	significant	ADJ
admet-159	142	20	difference	difference	NOUN
admet-159	142	21	between	between	ADP
admet-159	142	22	control	control	NOUN
admet-159	142	23	and	and	CCONJ
admet-159	142	24	mn	mn	PROPN
admet-159	142	25	-	-	PUNCT
admet-159	142	26	treated	treat	VERB
admet-159	142	27	groups	group	NOUN
admet-159	142	28	at	at	ADP
admet-159	142	29	24	24	NUM
admet-159	142	30	h	h	NOUN
admet-159	142	31	but	but	CCONJ
admet-159	142	32	did	do	AUX
admet-159	142	33	show	show	VERB
admet-159	142	34	a	a	DET
admet-159	142	35	significant	significant	ADJ
admet-159	142	36	decrease	decrease	NOUN
admet-159	142	37	at	at	ADP
admet-159	142	38	48	48	NUM
admet-159	142	39	h	h	NOUN
admet-159	142	40	(	(	PUNCT
admet-159	142	41	fig	fig	NOUN
admet-159	142	42	.	.	PUNCT
admet-159	142	43	2b	2b	NUM
admet-159	142	44	)	)	PUNCT
admet-159	142	45	.	.	PUNCT
admet-159	143	1	this	this	DET
admet-159	143	2	decrease	decrease	NOUN
admet-159	143	3	could	could	AUX
admet-159	143	4	be	be	AUX
admet-159	143	5	a	a	DET
admet-159	143	6	result	result	NOUN
admet-159	143	7	of	of	ADP
admet-159	143	8	the	the	DET
admet-159	143	9	clearing	clearing	NOUN
admet-159	143	10	of	of	ADP
admet-159	143	11	a	a	DET
admet-159	143	12	-	-	PUNCT
admet-159	143	13	syn	syn	NOUN
admet-159	143	14	aggregates	aggregate	NOUN
admet-159	143	15	,	,	PUNCT
admet-159	143	16	which	which	PRON
admet-159	143	17	has	have	AUX
admet-159	143	18	been	be	AUX
admet-159	143	19	shown	show	VERB
admet-159	143	20	to	to	PART
admet-159	143	21	occur	occur	VERB
admet-159	143	22	in	in	ADP
admet-159	143	23	the	the	DET
admet-159	143	24	presence	presence	NOUN
admet-159	143	25	of	of	ADP
admet-159	143	26	mn	mn	PROPN
admet-159	143	27	in	in	ADP
admet-159	143	28	neurons	neuron	NOUN
admet-159	143	29	[	[	X
admet-159	143	30	50	50	NUM
admet-159	143	31	]	]	PUNCT
admet-159	143	32	.	.	PUNCT
admet-159	144	1	the	the	DET
admet-159	144	2	decrease	decrease	NOUN
admet-159	144	3	in	in	ADP
admet-159	144	4	a	a	DET
admet-159	144	5	-	-	PUNCT
admet-159	144	6	syn	syn	NOUN
admet-159	144	7	signals	signal	NOUN
admet-159	144	8	,	,	PUNCT
admet-159	144	9	however	however	ADV
admet-159	144	10	,	,	PUNCT
admet-159	144	11	is	be	AUX
admet-159	144	12	contradictory	contradictory	ADJ
admet-159	144	13	to	to	ADP
admet-159	144	14	some	some	DET
admet-159	144	15	literature	literature	NOUN
admet-159	144	16	reports	report	NOUN
admet-159	144	17	,	,	PUNCT
admet-159	144	18	where	where	SCONJ
admet-159	144	19	a	a	X
admet-159	144	20	-	-	PUNCT
admet-159	144	21	syn	syn	NOUN
admet-159	144	22	overexpression	overexpression	NOUN
admet-159	144	23	following	follow	VERB
admet-159	144	24	mn	mn	PROPN
admet-159	144	25	exposure	exposure	NOUN
admet-159	144	26	was	be	AUX
admet-159	144	27	observed	observe	VERB
admet-159	144	28	in	in	ADP
admet-159	144	29	other	other	ADJ
admet-159	144	30	cell	cell	NOUN
admet-159	144	31	types	type	NOUN
admet-159	144	32	[	[	X
admet-159	144	33	40	40	NUM
admet-159	144	34	,	,	PUNCT
admet-159	144	35	41	41	NUM
admet-159	144	36	]	]	PUNCT
admet-159	144	37	.	.	PUNCT
admet-159	145	1	we	we	PRON
admet-159	145	2	further	far	ADV
admet-159	145	3	used	use	VERB
admet-159	145	4	qpcr	qpcr	ADV
admet-159	145	5	to	to	PART
admet-159	145	6	quantify	quantify	VERB
admet-159	145	7	a	a	DET
admet-159	145	8	-	-	PUNCT
admet-159	145	9	syn	syn	NOUN
admet-159	145	10	mrna	mrna	PROPN
admet-159	145	11	expression	expression	NOUN
admet-159	145	12	in	in	ADP
admet-159	145	13	z310	z310	PROPN
admet-159	145	14	cells	cell	NOUN
admet-159	145	15	with	with	ADP
admet-159	145	16	various	various	ADJ
admet-159	145	17	concentrations	concentration	NOUN
admet-159	145	18	of	of	ADP
admet-159	145	19	mn	mn	PROPN
admet-159	145	20	.	.	PUNCT
admet-159	146	1	after	after	ADP
admet-159	146	2	a	a	DET
admet-159	146	3	24	24	NUM
admet-159	146	4	h	h	NOUN
admet-159	146	5	treatment	treatment	NOUN
admet-159	146	6	,	,	PUNCT
admet-159	146	7	the	the	DET
admet-159	146	8	qpcr	qpcr	ADJ
admet-159	146	9	analysis	analysis	NOUN
admet-159	146	10	did	do	AUX
admet-159	146	11	not	not	PART
admet-159	146	12	reveal	reveal	VERB
admet-159	146	13	any	any	DET
admet-159	146	14	significant	significant	ADJ
admet-159	146	15	change	change	NOUN
admet-159	146	16	in	in	ADP
admet-159	146	17	a	a	DET
admet-159	146	18	-	-	PUNCT
admet-159	146	19	syn	syn	NOUN
admet-159	146	20	mrna	mrna	PROPN
admet-159	146	21	expression	expression	NOUN
admet-159	146	22	(	(	PUNCT
admet-159	146	23	fig	fig	NOUN
admet-159	146	24	.	.	PUNCT
admet-159	146	25	2c	2c	NUM
admet-159	146	26	)	)	PUNCT
admet-159	146	27	.	.	PUNCT
admet-159	147	1	these	these	DET
admet-159	147	2	data	datum	NOUN
admet-159	147	3	were	be	AUX
admet-159	147	4	consistent	consistent	ADJ
admet-159	147	5	with	with	ADP
admet-159	147	6	the	the	DET
admet-159	147	7	confocal	confocal	ADJ
admet-159	147	8	quantitation	quantitation	NOUN
admet-159	147	9	results	result	NOUN
admet-159	147	10	,	,	PUNCT
admet-159	147	11	supporting	support	VERB
admet-159	147	12	the	the	DET
admet-159	147	13	view	view	NOUN
admet-159	147	14	that	that	SCONJ
admet-159	147	15	mn	mn	PROPN
admet-159	147	16	exposure	exposure	NOUN
admet-159	147	17	did	do	AUX
admet-159	147	18	not	not	PART
admet-159	147	19	induce	induce	VERB
admet-159	147	20	a	a	DET
admet-159	147	21	-	-	PUNCT
admet-159	147	22	syn	syn	NOUN
admet-159	147	23	overexpression	overexpression	NOUN
admet-159	147	24	at	at	ADP
admet-159	147	25	either	either	CCONJ
admet-159	147	26	the	the	DET
admet-159	147	27	transcriptional	transcriptional	ADJ
admet-159	147	28	or	or	CCONJ
admet-159	147	29	translational	translational	ADJ
admet-159	147	30	level	level	NOUN
admet-159	147	31	.	.	PUNCT
admet-159	148	1	the	the	DET
admet-159	148	2	changes	change	NOUN
admet-159	148	3	in	in	ADP
admet-159	148	4	a	a	DET
admet-159	148	5	-	-	PUNCT
admet-159	148	6	syn	syn	NOUN
admet-159	148	7	signals	signal	NOUN
admet-159	148	8	in	in	ADP
admet-159	148	9	z310	z310	PROPN
admet-159	148	10	cells	cell	NOUN
admet-159	148	11	after	after	ADP
admet-159	148	12	mn	mn	PROPN
admet-159	148	13	exposure	exposure	NOUN
admet-159	148	14	may	may	AUX
admet-159	148	15	reflect	reflect	VERB
admet-159	148	16	a	a	DET
admet-159	148	17	direct	direct	ADJ
admet-159	148	18	interaction	interaction	NOUN
admet-159	148	19	of	of	ADP
admet-159	148	20	mn	mn	PROPN
admet-159	148	21	with	with	ADP
admet-159	148	22	asyn	asyn	PROPN
admet-159	148	23	.	.	PUNCT
admet-159	149	1	admet	admet	PROPN
admet-159	149	2	&	&	CCONJ
admet-159	149	3	dmpk	dmpk	PROPN
admet-159	149	4	3(1	3(1	NUM
admet-159	149	5	)	)	PUNCT
admet-159	149	6	(	(	PUNCT
admet-159	149	7	2015	2015	NUM
admet-159	149	8	)	)	PUNCT
admet-159	149	9	15	15	NUM
admet-159	149	10	-	-	SYM
admet-159	149	11	33	33	NUM
admet-159	149	12	effects	effect	NOUN
admet-159	149	13	of	of	ADP
admet-159	149	14	manganese	manganese	ADJ
admet-159	149	15	exposure	exposure	NOUN
admet-159	149	16	on	on	ADP
admet-159	149	17	expression	expression	NOUN
admet-159	149	18	and	and	CCONJ
admet-159	149	19	transport	transport	NOUN
admet-159	149	20	of	of	ADP
admet-159	149	21	-synuclein	-synuclein	PROPN
admet-159	149	22	doi	doi	NOUN
admet-159	149	23	:	:	PUNCT
admet-159	149	24	10.5599	10.5599	NUM
admet-159	149	25	/	/	SYM
admet-159	149	26	admet.3.1.159	admet.3.1.159	NUM
admet-159	149	27	21	21	NUM
admet-159	149	28	figure	figure	NOUN
admet-159	149	29	1	1	NUM
admet-159	149	30	.	.	PUNCT
admet-159	149	31	expression	expression	NOUN
admet-159	149	32	of	of	ADP
admet-159	149	33	endogenous	endogenous	ADJ
admet-159	149	34	a	a	PRON
admet-159	149	35	-	-	PUNCT
admet-159	149	36	syn	syn	NOUN
admet-159	149	37	in	in	ADP
admet-159	149	38	choroid	choroid	NOUN
admet-159	149	39	plexus	plexus	NOUN
admet-159	149	40	.	.	PUNCT
admet-159	150	1	(	(	PUNCT
admet-159	150	2	a	a	X
admet-159	150	3	)	)	PUNCT
admet-159	150	4	presence	presence	NOUN
admet-159	150	5	of	of	ADP
admet-159	150	6	a	a	DET
admet-159	150	7	-	-	PUNCT
admet-159	150	8	syn	syn	NOUN
admet-159	150	9	in	in	ADP
admet-159	150	10	rat	rat	NOUN
admet-159	150	11	choroid	choroid	NOUN
admet-159	150	12	plexus	plexus	NOUN
admet-159	150	13	tissue	tissue	NOUN
admet-159	150	14	.	.	PUNCT
admet-159	151	1	choroid	choroid	NOUN
admet-159	151	2	plexuses	plexus	NOUN
admet-159	151	3	were	be	AUX
admet-159	151	4	dissected	dissect	VERB
admet-159	151	5	from	from	ADP
admet-159	151	6	rats	rat	NOUN
admet-159	151	7	and	and	CCONJ
admet-159	151	8	stained	stain	VERB
admet-159	151	9	with	with	ADP
admet-159	151	10	primary	primary	ADJ
admet-159	151	11	anti	anti	ADJ
admet-159	151	12	-	-	ADJ
admet-159	151	13	a	a	DET
admet-159	151	14	-	-	PUNCT
admet-159	151	15	syn	syn	NOUN
admet-159	151	16	.	.	PUNCT
admet-159	152	1	a	a	DET
admet-159	152	2	typical	typical	ADJ
admet-159	152	3	image	image	NOUN
admet-159	152	4	from	from	ADP
admet-159	152	5	n	n	NOUN
admet-159	152	6	=	=	NUM
admet-159	152	7	4	4	NUM
admet-159	152	8	is	be	AUX
admet-159	152	9	presented	present	VERB
admet-159	152	10	.	.	PUNCT
admet-159	153	1	(	(	PUNCT
admet-159	153	2	b	b	X
admet-159	153	3	)	)	PUNCT
admet-159	153	4	presence	presence	NOUN
admet-159	153	5	of	of	ADP
admet-159	153	6	a	a	DET
admet-159	153	7	-	-	PUNCT
admet-159	153	8	syn	syn	NOUN
admet-159	153	9	in	in	ADP
admet-159	153	10	choroidal	choroidal	ADJ
admet-159	153	11	z310	z310	PROPN
admet-159	153	12	cells	cell	NOUN
admet-159	153	13	.	.	PUNCT
admet-159	154	1	z310	z310	PROPN
admet-159	154	2	cells	cell	NOUN
admet-159	154	3	were	be	AUX
admet-159	154	4	fixed	fix	VERB
admet-159	154	5	and	and	CCONJ
admet-159	154	6	stained	stain	VERB
admet-159	154	7	with	with	ADP
admet-159	154	8	primary	primary	ADJ
admet-159	154	9	anti	anti	ADJ
admet-159	154	10	-	-	ADJ
admet-159	154	11	a	a	DET
admet-159	154	12	-	-	PUNCT
admet-159	154	13	syn	syn	NOUN
admet-159	154	14	.	.	PUNCT
admet-159	155	1	a	a	DET
admet-159	155	2	typical	typical	ADJ
admet-159	155	3	image	image	NOUN
admet-159	155	4	from	from	ADP
admet-159	155	5	n	n	NOUN
admet-159	155	6	=	=	NUM
admet-159	155	7	4	4	NUM
admet-159	155	8	is	be	AUX
admet-159	155	9	presented	present	VERB
admet-159	155	10	.	.	PUNCT
admet-159	156	1	in	in	ADP
admet-159	156	2	both	both	DET
admet-159	156	3	tissues	tissue	NOUN
admet-159	156	4	and	and	CCONJ
admet-159	156	5	cells	cell	NOUN
admet-159	156	6	,	,	PUNCT
admet-159	156	7	a	a	DET
admet-159	156	8	-	-	PUNCT
admet-159	156	9	syn	syn	NOUN
admet-159	156	10	immunoreactivity	immunoreactivity	NOUN
admet-159	156	11	is	be	AUX
admet-159	156	12	evident	evident	ADJ
admet-159	156	13	in	in	ADP
admet-159	156	14	the	the	DET
admet-159	156	15	cytosol	cytosol	NOUN
admet-159	156	16	.	.	PUNCT
admet-159	157	1	scale	scale	NOUN
admet-159	157	2	bar	bar	NOUN
admet-159	157	3	:	:	PUNCT
admet-159	157	4	20	20	NUM
admet-159	157	5	μm	μm	NOUN
admet-159	157	6	.	.	PUNCT
admet-159	158	1	effects	effect	NOUN
admet-159	158	2	of	of	ADP
admet-159	158	3	cu	cu	PROPN
admet-159	158	4	treatment	treatment	NOUN
admet-159	158	5	on	on	ADP
admet-159	158	6	endogenous	endogenous	ADJ
admet-159	158	7	expression	expression	NOUN
admet-159	158	8	of	of	ADP
admet-159	158	9	a	a	DET
admet-159	158	10	-	-	PUNCT
admet-159	158	11	syn	syn	NOUN
admet-159	158	12	at	at	ADP
admet-159	158	13	the	the	DET
admet-159	158	14	bcsfb	bcsfb	PROPN
admet-159	158	15	recent	recent	ADJ
admet-159	158	16	findings	finding	NOUN
admet-159	158	17	in	in	ADP
admet-159	158	18	our	our	PRON
admet-159	158	19	lab	lab	NOUN
admet-159	158	20	have	have	AUX
admet-159	158	21	shown	show	VERB
admet-159	158	22	that	that	SCONJ
admet-159	158	23	mn	mn	PROPN
admet-159	158	24	accumulation	accumulation	NOUN
admet-159	158	25	in	in	ADP
admet-159	158	26	the	the	DET
admet-159	158	27	choroid	choroid	NOUN
admet-159	158	28	plexus	plexus	NOUN
admet-159	158	29	can	can	AUX
admet-159	158	30	cause	cause	VERB
admet-159	158	31	cu	cu	NOUN
admet-159	158	32	dyshomeostasis	dyshomeostasis	NOUN
admet-159	158	33	in	in	ADP
admet-159	158	34	the	the	DET
admet-159	158	35	bcsfb	bcsfb	NOUN
admet-159	158	36	[	[	X
admet-159	158	37	29	29	NUM
admet-159	158	38	]	]	PUNCT
admet-159	158	39	.	.	PUNCT
admet-159	159	1	cu	cu	PROPN
admet-159	159	2	itself	itself	PRON
admet-159	159	3	has	have	AUX
admet-159	159	4	been	be	AUX
admet-159	159	5	shown	show	VERB
admet-159	159	6	to	to	PART
admet-159	159	7	induce	induce	VERB
admet-159	159	8	a	a	DET
admet-159	159	9	-	-	PUNCT
admet-159	159	10	syn	syn	NOUN
admet-159	159	11	aggregation	aggregation	NOUN
admet-159	159	12	and	and	CCONJ
admet-159	159	13	dysfunction	dysfunction	NOUN
admet-159	159	14	[	[	X
admet-159	159	15	38,39,51	38,39,51	NUM
admet-159	159	16	]	]	PUNCT
admet-159	159	17	.	.	PUNCT
admet-159	160	1	to	to	PART
admet-159	160	2	compare	compare	VERB
admet-159	160	3	with	with	ADP
admet-159	160	4	the	the	DET
admet-159	160	5	mn	mn	PROPN
admet-159	160	6	effects	effect	NOUN
admet-159	160	7	outlined	outline	VERB
admet-159	160	8	in	in	ADP
admet-159	160	9	the	the	DET
admet-159	160	10	previous	previous	ADJ
admet-159	160	11	section	section	NOUN
admet-159	160	12	,	,	PUNCT
admet-159	160	13	we	we	PRON
admet-159	160	14	sought	seek	VERB
admet-159	160	15	to	to	PART
admet-159	160	16	investigate	investigate	VERB
admet-159	160	17	the	the	DET
admet-159	160	18	effect	effect	NOUN
admet-159	160	19	of	of	ADP
admet-159	160	20	cu	cu	PROPN
admet-159	160	21	on	on	ADP
admet-159	160	22	endogenous	endogenous	ADJ
admet-159	160	23	a	a	PRON
admet-159	160	24	-	-	PUNCT
admet-159	160	25	syn	syn	NOUN
admet-159	160	26	expression	expression	NOUN
admet-159	160	27	in	in	ADP
admet-159	160	28	the	the	DET
admet-159	160	29	plexus	plexus	NOUN
admet-159	160	30	cells	cell	NOUN
admet-159	160	31	.	.	PUNCT
admet-159	161	1	after	after	SCONJ
admet-159	161	2	z310	z310	PROPN
admet-159	161	3	cells	cell	NOUN
admet-159	161	4	were	be	AUX
admet-159	161	5	incubated	incubate	VERB
admet-159	161	6	with	with	ADP
admet-159	161	7	50	50	NUM
admet-159	161	8	and	and	CCONJ
admet-159	161	9	100	100	NUM
admet-159	161	10	μm	μm	NUM
admet-159	161	11	cucl2	cucl2	NOUN
admet-159	161	12	for	for	ADP
admet-159	161	13	24	24	NUM
admet-159	161	14	h	h	NOUN
admet-159	161	15	,	,	PUNCT
admet-159	161	16	bright	bright	ADJ
admet-159	161	17	dots	dot	NOUN
admet-159	161	18	were	be	AUX
admet-159	161	19	also	also	ADV
admet-159	161	20	observed	observe	VERB
admet-159	161	21	in	in	ADP
admet-159	161	22	the	the	DET
admet-159	161	23	cytoplasm	cytoplasm	NOUN
admet-159	161	24	of	of	ADP
admet-159	161	25	z310	z310	PROPN
admet-159	161	26	cells	cell	NOUN
admet-159	161	27	,	,	PUNCT
admet-159	161	28	similar	similar	ADJ
admet-159	161	29	to	to	ADP
admet-159	161	30	those	those	PRON
admet-159	161	31	in	in	ADP
admet-159	161	32	the	the	DET
admet-159	161	33	mn	mn	PROPN
admet-159	161	34	exposed	expose	VERB
admet-159	161	35	group	group	NOUN
admet-159	161	36	(	(	PUNCT
admet-159	161	37	fig	fig	NOUN
admet-159	161	38	.	.	PUNCT
admet-159	162	1	3a	3a	NUM
admet-159	162	2	)	)	PUNCT
admet-159	162	3	.	.	PUNCT
admet-159	163	1	confocal	confocal	ADJ
admet-159	163	2	quantitation	quantitation	NOUN
admet-159	163	3	of	of	ADP
admet-159	163	4	asyn	asyn	ADJ
admet-159	163	5	signals	signal	NOUN
admet-159	163	6	revealed	reveal	VERB
admet-159	163	7	that	that	SCONJ
admet-159	163	8	cells	cell	NOUN
admet-159	163	9	exposed	expose	VERB
admet-159	163	10	to	to	ADP
admet-159	163	11	50	50	NUM
admet-159	163	12	μm	μm	NOUN
admet-159	163	13	cucl2	cucl2	NOUN
admet-159	163	14	displayed	display	VERB
admet-159	163	15	a	a	DET
admet-159	163	16	significant	significant	ADJ
admet-159	163	17	increase	increase	NOUN
admet-159	163	18	in	in	ADP
admet-159	163	19	a	a	DET
admet-159	163	20	-	-	PUNCT
admet-159	163	21	syn	syn	NOUN
admet-159	163	22	intensity	intensity	NOUN
admet-159	163	23	(	(	PUNCT
admet-159	163	24	fig	fig	NOUN
admet-159	163	25	.	.	PUNCT
admet-159	164	1	3b	3b	NUM
admet-159	164	2	)	)	PUNCT
admet-159	164	3	.	.	PUNCT
admet-159	165	1	a	a	DET
admet-159	165	2	)	)	PUNCT
admet-159	165	3	b	b	NOUN
admet-159	165	4	)	)	PUNCT
admet-159	165	5	bates	bate	NOUN
admet-159	165	6	et	et	PROPN
admet-159	165	7	al	al	PROPN
admet-159	165	8	.	.	PROPN
admet-159	165	9	admet	admet	PROPN
admet-159	165	10	&	&	CCONJ
admet-159	165	11	dmpk	dmpk	PROPN
admet-159	165	12	3(1	3(1	NUM
admet-159	165	13	)	)	PUNCT
admet-159	165	14	(	(	PUNCT
admet-159	165	15	2015	2015	NUM
admet-159	165	16	)	)	PUNCT
admet-159	165	17	15	15	NUM
admet-159	165	18	-	-	SYM
admet-159	165	19	33	33	NUM
admet-159	165	20	22	22	NUM
admet-159	165	21	figure	figure	NOUN
admet-159	165	22	2	2	NUM
admet-159	165	23	.	.	PUNCT
admet-159	165	24	endogenous	endogenous	ADJ
admet-159	165	25	a	a	PRON
admet-159	165	26	-	-	PUNCT
admet-159	165	27	syn	syn	NOUN
admet-159	165	28	expression	expression	NOUN
admet-159	165	29	in	in	ADP
admet-159	165	30	z310	z310	PROPN
admet-159	165	31	cells	cell	NOUN
admet-159	165	32	following	follow	VERB
admet-159	165	33	mn	mn	PROPN
admet-159	165	34	exposure	exposure	NOUN
admet-159	165	35	.	.	PUNCT
admet-159	166	1	(	(	PUNCT
admet-159	166	2	a	a	X
admet-159	166	3	)	)	PUNCT
admet-159	166	4	ihc	ihc	PROPN
admet-159	166	5	staining	staining	NOUN
admet-159	166	6	of	of	ADP
admet-159	166	7	a	a	DET
admet-159	166	8	-	-	PUNCT
admet-159	166	9	syn	syn	NOUN
admet-159	166	10	in	in	ADP
admet-159	166	11	z310	z310	PROPN
admet-159	166	12	cells	cell	NOUN
admet-159	166	13	.	.	PUNCT
admet-159	167	1	z310	z310	PROPN
admet-159	167	2	cells	cell	NOUN
admet-159	167	3	were	be	AUX
admet-159	167	4	treated	treat	VERB
admet-159	167	5	with	with	ADP
admet-159	167	6	100	100	NUM
admet-159	167	7	μm	μm	NUM
admet-159	167	8	mncl2	mncl2	NOUN
admet-159	167	9	for	for	ADP
admet-159	167	10	24	24	NUM
admet-159	167	11	and	and	CCONJ
admet-159	167	12	48	48	NUM
admet-159	167	13	h.	h.	NOUN
admet-159	167	14	the	the	DET
admet-159	167	15	white	white	PROPN
admet-159	167	16	circle	circle	PROPN
admet-159	167	17	indicates	indicate	VERB
admet-159	167	18	that	that	SCONJ
admet-159	167	19	at	at	ADP
admet-159	167	20	48	48	NUM
admet-159	167	21	h	h	NOUN
admet-159	167	22	after	after	ADP
admet-159	167	23	mn	mn	PROPN
admet-159	167	24	treatment	treatment	NOUN
admet-159	167	25	,	,	PUNCT
admet-159	167	26	bright	bright	ADJ
admet-159	167	27	green	green	ADJ
admet-159	167	28	puncta	puncta	NOUN
admet-159	167	29	were	be	AUX
admet-159	167	30	formed	form	VERB
admet-159	167	31	in	in	ADP
admet-159	167	32	the	the	DET
admet-159	167	33	cytoplasm	cytoplasm	NOUN
admet-159	167	34	.	.	PUNCT
admet-159	168	1	data	datum	NOUN
admet-159	168	2	represent	represent	VERB
admet-159	168	3	a	a	DET
admet-159	168	4	typical	typical	ADJ
admet-159	168	5	study	study	NOUN
admet-159	168	6	of	of	ADP
admet-159	168	7	n	n	NOUN
admet-159	168	8	=	=	SYM
admet-159	168	9	4	4	NUM
admet-159	168	10	.	.	NOUN
admet-159	168	11	scale	scale	NOUN
admet-159	168	12	bar	bar	NOUN
admet-159	168	13	:	:	PUNCT
admet-159	168	14	20	20	NUM
admet-159	168	15	μm	μm	NOUN
admet-159	168	16	.	.	PUNCT
admet-159	169	1	(	(	PUNCT
admet-159	169	2	b	b	X
admet-159	169	3	)	)	PUNCT
admet-159	169	4	confocal	confocal	ADJ
admet-159	169	5	quantification	quantification	NOUN
admet-159	169	6	of	of	ADP
admet-159	169	7	endogenous	endogenous	ADJ
admet-159	169	8	a	a	PRON
admet-159	169	9	-	-	PUNCT
admet-159	169	10	syn	syn	NOUN
admet-159	169	11	expression	expression	NOUN
admet-159	169	12	in	in	ADP
admet-159	169	13	z310	z310	PROPN
admet-159	169	14	cells	cell	NOUN
admet-159	169	15	following	follow	VERB
admet-159	169	16	mn	mn	PROPN
admet-159	169	17	exposure	exposure	NOUN
admet-159	169	18	.	.	PUNCT
admet-159	170	1	data	datum	NOUN
admet-159	170	2	represent	represent	VERB
admet-159	170	3	mean	mean	PROPN
admet-159	170	4	±sd	±sd	PROPN
admet-159	170	5	.	.	PUNCT
admet-159	171	1	n	n	NOUN
admet-159	171	2	=	=	SYM
admet-159	171	3	15	15	NUM
admet-159	171	4	-	-	SYM
admet-159	171	5	27	27	NUM
admet-159	171	6	.	.	PUNCT
admet-159	172	1	*	*	PUNCT
admet-159	172	2	:	:	PUNCT
admet-159	172	3	p<0.05	p<0.05	NOUN
admet-159	172	4	as	as	SCONJ
admet-159	172	5	compared	compare	VERB
admet-159	172	6	to	to	PART
admet-159	172	7	ctrl	ctrl	VERB
admet-159	172	8	.	.	PUNCT
admet-159	173	1	#	#	SYM
admet-159	173	2	#	#	NOUN
admet-159	173	3	:	:	PUNCT
admet-159	173	4	p<0.01	p<0.01	PROPN
admet-159	173	5	as	as	SCONJ
admet-159	173	6	compared	compare	VERB
admet-159	173	7	to	to	ADP
admet-159	173	8	data	datum	NOUN
admet-159	173	9	at	at	ADP
admet-159	173	10	24	24	NUM
admet-159	173	11	h.	h.	NOUN
admet-159	173	12	(	(	PUNCT
admet-159	173	13	c	c	NOUN
admet-159	173	14	)	)	PUNCT
admet-159	173	15	expression	expression	NOUN
admet-159	173	16	of	of	ADP
admet-159	173	17	endogenous	endogenous	ADJ
admet-159	173	18	a	a	PRON
admet-159	173	19	-	-	PUNCT
admet-159	173	20	syn	syn	NOUN
admet-159	173	21	mrna	mrna	NOUN
admet-159	173	22	in	in	ADP
admet-159	173	23	z310	z310	PROPN
admet-159	173	24	cells	cell	NOUN
admet-159	173	25	following	follow	VERB
admet-159	173	26	mn	mn	PROPN
admet-159	173	27	exposure	exposure	NOUN
admet-159	173	28	.	.	PUNCT
admet-159	174	1	z310	z310	PROPN
admet-159	174	2	cells	cell	NOUN
admet-159	174	3	were	be	AUX
admet-159	174	4	treated	treat	VERB
admet-159	174	5	with	with	ADP
admet-159	174	6	25	25	NUM
admet-159	174	7	,	,	PUNCT
admet-159	174	8	50	50	NUM
admet-159	174	9	,	,	PUNCT
admet-159	174	10	or	or	CCONJ
admet-159	174	11	100	100	NUM
admet-159	174	12	μm	μm	NUM
admet-159	174	13	mncl2	mncl2	NOUN
admet-159	174	14	for	for	ADP
admet-159	174	15	24	24	NUM
admet-159	174	16	h.	h.	PROPN
admet-159	174	17	the	the	DET
admet-159	174	18	mrna	mrna	PROPN
admet-159	174	19	levels	level	NOUN
admet-159	174	20	were	be	AUX
admet-159	174	21	quantified	quantify	VERB
admet-159	174	22	by	by	ADP
admet-159	174	23	qpcr	qpcr	ADV
admet-159	174	24	.	.	PUNCT
admet-159	175	1	data	datum	NOUN
admet-159	175	2	represent	represent	VERB
admet-159	175	3	mean	mean	PROPN
admet-159	175	4	±	±	NUM
admet-159	175	5	sd	sd	NOUN
admet-159	175	6	;	;	PUNCT
admet-159	175	7	n	n	NOUN
admet-159	175	8	=	=	SYM
admet-159	175	9	4	4	X
admet-159	175	10	.	.	PUNCT
admet-159	175	11	aggregation	aggregation	NOUN
admet-159	175	12	of	of	ADP
admet-159	175	13	a	a	DET
admet-159	175	14	-	-	PUNCT
admet-159	175	15	syn	syn	NOUN
admet-159	175	16	following	follow	VERB
admet-159	175	17	mn	mn	PROPN
admet-159	175	18	and	and	CCONJ
admet-159	175	19	cu	cu	PROPN
admet-159	175	20	treatment	treatment	NOUN
admet-159	175	21	results	result	NOUN
admet-159	175	22	so	so	ADV
admet-159	175	23	far	far	ADV
admet-159	175	24	appeared	appear	VERB
admet-159	175	25	to	to	PART
admet-159	175	26	suggest	suggest	VERB
admet-159	175	27	a	a	DET
admet-159	175	28	direct	direct	ADJ
admet-159	175	29	,	,	PUNCT
admet-159	175	30	physicochemical	physicochemical	ADJ
admet-159	175	31	interaction	interaction	NOUN
admet-159	175	32	between	between	ADP
admet-159	175	33	a	a	PROPN
admet-159	175	34	-	-	PUNCT
admet-159	175	35	syn	syn	PROPN
admet-159	175	36	,	,	PUNCT
admet-159	175	37	mn	mn	PROPN
admet-159	175	38	,	,	PUNCT
admet-159	175	39	and/or	and/or	CCONJ
admet-159	175	40	cu	cu	PROPN
admet-159	175	41	.	.	PROPN
admet-159	176	1	thioflavin	thioflavin	PROPN
admet-159	176	2	t	t	PROPN
admet-159	176	3	(	(	PUNCT
admet-159	176	4	thiot	thiot	NOUN
admet-159	176	5	)	)	PUNCT
admet-159	176	6	has	have	AUX
admet-159	176	7	been	be	AUX
admet-159	176	8	used	use	VERB
admet-159	176	9	extensively	extensively	ADV
admet-159	176	10	in	in	ADP
admet-159	176	11	previous	previous	ADJ
admet-159	176	12	studies	study	NOUN
admet-159	176	13	to	to	PART
admet-159	176	14	assess	assess	VERB
admet-159	176	15	metal	metal	NOUN
admet-159	176	16	-	-	PUNCT
admet-159	176	17	induced	induce	VERB
admet-159	176	18	aggregation	aggregation	NOUN
admet-159	176	19	of	of	ADP
admet-159	176	20	asyn	asyn	PROPN
admet-159	177	1	[	[	X
admet-159	177	2	38,39	38,39	NOUN
admet-159	177	3	]	]	X
admet-159	177	4	.	.	PUNCT
admet-159	178	1	in	in	ADP
admet-159	178	2	the	the	DET
admet-159	178	3	current	current	ADJ
admet-159	178	4	study	study	NOUN
admet-159	178	5	,	,	PUNCT
admet-159	178	6	we	we	PRON
admet-159	178	7	incubated	incubate	VERB
admet-159	178	8	recombinant	recombinant	ADJ
admet-159	178	9	human	human	ADJ
admet-159	178	10	a	a	PROPN
admet-159	178	11	-	-	PUNCT
admet-159	178	12	syn	syn	NOUN
admet-159	178	13	with	with	ADP
admet-159	178	14	mn	mn	PROPN
admet-159	178	15	,	,	PUNCT
admet-159	178	16	cu	cu	PROPN
admet-159	178	17	,	,	PUNCT
admet-159	178	18	or	or	CCONJ
admet-159	178	19	a	a	DET
admet-159	178	20	combination	combination	NOUN
admet-159	178	21	of	of	ADP
admet-159	178	22	mn	mn	PROPN
admet-159	178	23	and	and	CCONJ
admet-159	178	24	cu	cu	PROPN
admet-159	178	25	at	at	ADP
admet-159	178	26	a	a	DET
admet-159	178	27	concentration	concentration	NOUN
admet-159	178	28	of	of	ADP
admet-159	178	29	100	100	NUM
admet-159	178	30	μm	μm	NOUN
admet-159	179	1	[	[	X
admet-159	179	2	38,39	38,39	NOUN
admet-159	179	3	]	]	PUNCT
admet-159	179	4	and	and	CCONJ
admet-159	179	5	used	use	VERB
admet-159	179	6	thiot	thiot	NOUN
admet-159	179	7	to	to	PART
admet-159	179	8	determine	determine	VERB
admet-159	179	9	the	the	DET
admet-159	179	10	metal	metal	NOUN
admet-159	179	11	effects	effect	NOUN
admet-159	179	12	on	on	ADP
admet-159	179	13	a	a	DET
admet-159	179	14	-	-	PUNCT
admet-159	179	15	syn	syn	NOUN
admet-159	179	16	aggregation	aggregation	NOUN
admet-159	179	17	in	in	ADP
admet-159	179	18	vitro	vitro	X
admet-159	179	19	.	.	PUNCT
admet-159	180	1	results	result	NOUN
admet-159	180	2	presented	present	VERB
admet-159	180	3	in	in	ADP
admet-159	180	4	fig	fig	NOUN
admet-159	180	5	.	.	PUNCT
admet-159	181	1	4	4	NUM
admet-159	181	2	showed	show	VERB
admet-159	181	3	a	a	DET
admet-159	181	4	drastic	drastic	ADJ
admet-159	181	5	decrease	decrease	NOUN
admet-159	181	6	in	in	ADP
admet-159	181	7	the	the	DET
admet-159	181	8	maximal	maximal	ADJ
admet-159	181	9	(	(	PUNCT
admet-159	181	10	final	final	ADJ
admet-159	181	11	)	)	PUNCT
admet-159	181	12	fluorescence	fluorescence	NOUN
admet-159	181	13	of	of	ADP
admet-159	181	14	a	a	PROPN
admet-159	181	15	-	-	PUNCT
admet-159	181	16	syn	syn	NOUN
admet-159	181	17	when	when	SCONJ
admet-159	181	18	incubated	incubate	VERB
admet-159	181	19	with	with	ADP
admet-159	181	20	mn	mn	PROPN
admet-159	181	21	,	,	PUNCT
admet-159	181	22	cu	cu	PROPN
admet-159	181	23	,	,	PUNCT
admet-159	181	24	or	or	CCONJ
admet-159	181	25	the	the	DET
admet-159	181	26	combination	combination	NOUN
admet-159	181	27	of	of	ADP
admet-159	181	28	the	the	DET
admet-159	181	29	two	two	NUM
admet-159	181	30	metals	metal	NOUN
admet-159	181	31	(	(	PUNCT
admet-159	181	32	data	datum	NOUN
admet-159	181	33	not	not	PART
admet-159	181	34	shown	show	VERB
admet-159	181	35	)	)	PUNCT
admet-159	181	36	.	.	PUNCT
admet-159	182	1	this	this	DET
admet-159	182	2	quenching	quenching	NOUN
admet-159	182	3	of	of	ADP
admet-159	182	4	fluorescence	fluorescence	NOUN
admet-159	182	5	was	be	AUX
admet-159	182	6	an	an	DET
admet-159	182	7	indication	indication	NOUN
admet-159	182	8	of	of	ADP
admet-159	182	9	a	a	DET
admet-159	182	10	structural	structural	ADJ
admet-159	182	11	change	change	NOUN
admet-159	182	12	of	of	ADP
admet-159	182	13	a	a	DET
admet-159	182	14	-	-	PUNCT
admet-159	182	15	syn	syn	NOUN
admet-159	182	16	and	and	CCONJ
admet-159	182	17	its	its	PRON
admet-159	182	18	aggregated	aggregate	VERB
admet-159	182	19	forms	form	NOUN
admet-159	182	20	in	in	ADP
admet-159	182	21	the	the	DET
admet-159	182	22	presence	presence	NOUN
admet-159	182	23	of	of	ADP
admet-159	182	24	these	these	DET
admet-159	182	25	metals	metal	NOUN
admet-159	182	26	[	[	X
admet-159	182	27	38	38	NUM
admet-159	182	28	]	]	PUNCT
admet-159	182	29	.	.	PUNCT
admet-159	183	1	when	when	SCONJ
admet-159	183	2	the	the	DET
admet-159	183	3	groups	group	NOUN
admet-159	183	4	were	be	AUX
admet-159	183	5	normalized	normalize	VERB
admet-159	183	6	to	to	ADP
admet-159	183	7	their	their	PRON
admet-159	183	8	respective	respective	ADJ
admet-159	183	9	maximum	maximum	ADJ
admet-159	183	10	fluorescence	fluorescence	NOUN
admet-159	183	11	intensities	intensity	NOUN
admet-159	183	12	,	,	PUNCT
admet-159	183	13	the	the	DET
admet-159	183	14	results	result	NOUN
admet-159	183	15	revealed	reveal	VERB
admet-159	183	16	that	that	SCONJ
admet-159	183	17	the	the	DET
admet-159	183	18	emergence	emergence	NOUN
admet-159	183	19	of	of	ADP
admet-159	183	20	a	a	PRON
admet-159	183	21	-	-	PUNCT
admet-159	183	22	syn	syn	NOUN
admet-159	183	23	fluorescence	fluorescence	NOUN
admet-159	183	24	occurred	occur	VERB
admet-159	183	25	much	much	ADV
admet-159	183	26	earlier	early	ADV
admet-159	183	27	,	,	PUNCT
admet-159	183	28	within	within	ADP
admet-159	183	29	5	5	NUM
admet-159	183	30	h	h	NOUN
admet-159	183	31	when	when	SCONJ
admet-159	183	32	a	a	X
admet-159	183	33	-	-	PUNCT
admet-159	183	34	syn	syn	NOUN
admet-159	183	35	was	be	AUX
admet-159	183	36	incubated	incubate	VERB
admet-159	183	37	with	with	ADP
admet-159	183	38	mn	mn	PROPN
admet-159	183	39	or	or	CCONJ
admet-159	183	40	cu	cu	PROPN
admet-159	183	41	alone	alone	ADV
admet-159	183	42	,	,	PUNCT
admet-159	183	43	compared	compare	VERB
admet-159	183	44	to	to	ADP
admet-159	183	45	a	a	DET
admet-159	183	46	-	-	PUNCT
admet-159	183	47	syn	syn	NOUN
admet-159	183	48	alone	alone	ADJ
admet-159	183	49	at	at	ADP
admet-159	183	50	about	about	ADV
admet-159	183	51	10	10	NUM
admet-159	183	52	h	h	NOUN
admet-159	183	53	(	(	PUNCT
admet-159	183	54	fig	fig	NOUN
admet-159	183	55	.	.	PUNCT
admet-159	183	56	4	4	NUM
admet-159	183	57	)	)	PUNCT
admet-159	183	58	.	.	PUNCT
admet-159	184	1	unexpectedly	unexpectedly	ADV
admet-159	184	2	,	,	PUNCT
admet-159	184	3	however	however	ADV
admet-159	184	4	,	,	PUNCT
admet-159	184	5	co	co	NOUN
admet-159	184	6	-	-	NOUN
admet-159	184	7	incubation	incubation	NOUN
admet-159	184	8	of	of	ADP
admet-159	184	9	a	a	DET
admet-159	184	10	-	-	PUNCT
admet-159	184	11	syn	syn	NOUN
admet-159	184	12	with	with	ADP
admet-159	184	13	both	both	DET
admet-159	184	14	mn	mn	PROPN
admet-159	184	15	and	and	CCONJ
admet-159	184	16	cu	cu	PROPN
admet-159	184	17	did	do	AUX
admet-159	184	18	not	not	PART
admet-159	184	19	show	show	VERB
admet-159	184	20	an	an	DET
admet-159	184	21	additive	additive	ADJ
admet-159	184	22	effect	effect	NOUN
admet-159	184	23	,	,	PUNCT
admet-159	184	24	but	but	CCONJ
admet-159	184	25	rather	rather	ADV
admet-159	184	26	it	it	PRON
admet-159	184	27	counteracted	counteract	VERB
admet-159	184	28	each	each	DET
admet-159	184	29	metal	metal	NOUN
admet-159	184	30	’s	’s	PART
admet-159	184	31	individual	individual	ADJ
admet-159	184	32	effect	effect	NOUN
admet-159	184	33	by	by	ADP
admet-159	184	34	slowing	slow	VERB
admet-159	184	35	the	the	DET
admet-159	184	36	increase	increase	NOUN
admet-159	184	37	of	of	ADP
admet-159	184	38	a	a	DET
admet-159	184	39	-	-	PUNCT
admet-159	184	40	syn	syn	NOUN
admet-159	184	41	fluorescence	fluorescence	NOUN
admet-159	184	42	(	(	PUNCT
admet-159	184	43	fig	fig	NOUN
admet-159	184	44	.	.	PUNCT
admet-159	184	45	4	4	NUM
admet-159	184	46	)	)	PUNCT
admet-159	184	47	.	.	PUNCT
admet-159	185	1	this	this	DET
admet-159	185	2	finding	finding	NOUN
admet-159	185	3	suggests	suggest	VERB
admet-159	185	4	that	that	SCONJ
admet-159	185	5	both	both	DET
admet-159	185	6	metals	metal	NOUN
admet-159	185	7	likely	likely	ADV
admet-159	185	8	bind	bind	VERB
admet-159	185	9	to	to	ADP
admet-159	185	10	a	a	DET
admet-159	185	11	-	-	PUNCT
admet-159	185	12	syn	syn	NOUN
admet-159	185	13	,	,	PUNCT
admet-159	185	14	inducing	induce	VERB
admet-159	185	15	altered	alter	VERB
admet-159	185	16	a	a	DET
admet-159	185	17	)	)	PUNCT
admet-159	185	18	b	b	NOUN
admet-159	185	19	)	)	PUNCT
admet-159	185	20	c	c	NOUN
admet-159	185	21	)	)	PUNCT
admet-159	185	22	*	*	PUNCT
admet-159	186	1	#	#	SYM
admet-159	186	2	#	#	NOUN
admet-159	186	3	admet	admet	NOUN
admet-159	186	4	&	&	CCONJ
admet-159	186	5	dmpk	dmpk	PROPN
admet-159	186	6	3(1	3(1	NUM
admet-159	186	7	)	)	PUNCT
admet-159	186	8	(	(	PUNCT
admet-159	186	9	2015	2015	NUM
admet-159	186	10	)	)	PUNCT
admet-159	186	11	15	15	NUM
admet-159	186	12	-	-	SYM
admet-159	186	13	33	33	NUM
admet-159	186	14	effects	effect	NOUN
admet-159	186	15	of	of	ADP
admet-159	186	16	manganese	manganese	ADJ
admet-159	186	17	exposure	exposure	NOUN
admet-159	186	18	on	on	ADP
admet-159	186	19	expression	expression	NOUN
admet-159	186	20	and	and	CCONJ
admet-159	186	21	transport	transport	NOUN
admet-159	186	22	of	of	ADP
admet-159	186	23	-synuclein	-synuclein	PROPN
admet-159	186	24	doi	doi	NOUN
admet-159	186	25	:	:	PUNCT
admet-159	186	26	10.5599	10.5599	NUM
admet-159	186	27	/	/	SYM
admet-159	186	28	admet.3.1.159	admet.3.1.159	NUM
admet-159	186	29	23	23	NUM
admet-159	186	30	conformations	conformation	NOUN
admet-159	186	31	of	of	ADP
admet-159	186	32	a	a	DET
admet-159	186	33	-	-	PUNCT
admet-159	186	34	syn	syn	NOUN
admet-159	186	35	aggregates	aggregate	NOUN
admet-159	186	36	.	.	PUNCT
admet-159	187	1	to	to	PART
admet-159	187	2	substantiate	substantiate	VERB
admet-159	187	3	this	this	DET
admet-159	187	4	finding	finding	NOUN
admet-159	187	5	,	,	PUNCT
admet-159	187	6	experiments	experiment	NOUN
admet-159	187	7	beyond	beyond	ADP
admet-159	187	8	thiot	thiot	NOUN
admet-159	187	9	,	,	PUNCT
admet-159	187	10	e.g.	e.g.	ADV
admet-159	187	11	,	,	PUNCT
admet-159	187	12	nmr	nmr	NOUN
admet-159	187	13	,	,	PUNCT
admet-159	187	14	should	should	AUX
admet-159	187	15	be	be	AUX
admet-159	187	16	conducted	conduct	VERB
admet-159	187	17	.	.	PUNCT
admet-159	188	1	figure	figure	VERB
admet-159	188	2	3	3	NUM
admet-159	188	3	.	.	PUNCT
admet-159	189	1	expression	expression	NOUN
admet-159	189	2	of	of	ADP
admet-159	189	3	a	a	DET
admet-159	189	4	-	-	PUNCT
admet-159	189	5	syn	syn	NOUN
admet-159	189	6	in	in	ADP
admet-159	189	7	z310	z310	PROPN
admet-159	189	8	cells	cell	NOUN
admet-159	189	9	following	follow	VERB
admet-159	189	10	cu	cu	PROPN
admet-159	189	11	treatment	treatment	NOUN
admet-159	189	12	.	.	PUNCT
admet-159	190	1	(	(	PUNCT
admet-159	190	2	a	a	X
admet-159	190	3	)	)	PUNCT
admet-159	190	4	ihc	ihc	PROPN
admet-159	190	5	staining	staining	NOUN
admet-159	190	6	of	of	ADP
admet-159	190	7	a	a	DET
admet-159	190	8	-	-	PUNCT
admet-159	190	9	syn	syn	NOUN
admet-159	190	10	in	in	ADP
admet-159	190	11	z310	z310	PROPN
admet-159	190	12	cells	cell	NOUN
admet-159	190	13	.	.	PUNCT
admet-159	191	1	z310	z310	PROPN
admet-159	191	2	cells	cell	NOUN
admet-159	191	3	were	be	AUX
admet-159	191	4	treated	treat	VERB
admet-159	191	5	with	with	ADP
admet-159	191	6	50	50	NUM
admet-159	191	7	or	or	CCONJ
admet-159	191	8	100	100	NUM
admet-159	191	9	μm	μm	NUM
admet-159	191	10	cucl2	cucl2	NOUN
admet-159	191	11	for	for	ADP
admet-159	191	12	24	24	NUM
admet-159	191	13	h.	h.	NOUN
admet-159	191	14	the	the	DET
admet-159	191	15	white	white	ADJ
admet-159	191	16	circles	circle	NOUN
admet-159	191	17	indicate	indicate	VERB
admet-159	191	18	that	that	SCONJ
admet-159	191	19	after	after	ADP
admet-159	191	20	cu	cu	PROPN
admet-159	191	21	treatment	treatment	NOUN
admet-159	191	22	,	,	PUNCT
admet-159	191	23	bright	bright	ADJ
admet-159	191	24	green	green	ADJ
admet-159	191	25	puncta	puncta	NOUN
admet-159	191	26	were	be	AUX
admet-159	191	27	formed	form	VERB
admet-159	191	28	in	in	ADP
admet-159	191	29	the	the	DET
admet-159	191	30	cytoplasm	cytoplasm	NOUN
admet-159	191	31	.	.	PUNCT
admet-159	192	1	data	datum	NOUN
admet-159	192	2	represent	represent	VERB
admet-159	192	3	a	a	DET
admet-159	192	4	typical	typical	ADJ
admet-159	192	5	study	study	NOUN
admet-159	192	6	of	of	ADP
admet-159	192	7	n	n	NOUN
admet-159	192	8	=	=	SYM
admet-159	192	9	4	4	NUM
admet-159	192	10	.	.	PUNCT
admet-159	192	11	(	(	PUNCT
admet-159	192	12	b	b	X
admet-159	192	13	)	)	PUNCT
admet-159	192	14	confocal	confocal	ADJ
admet-159	192	15	quantification	quantification	NOUN
admet-159	192	16	of	of	ADP
admet-159	192	17	endogenous	endogenous	ADJ
admet-159	192	18	a	a	PRON
admet-159	192	19	-	-	PUNCT
admet-159	192	20	syn	syn	NOUN
admet-159	192	21	expression	expression	NOUN
admet-159	192	22	in	in	ADP
admet-159	192	23	z310	z310	PROPN
admet-159	192	24	cells	cell	NOUN
admet-159	192	25	following	follow	VERB
admet-159	192	26	cu	cu	PROPN
admet-159	192	27	treatment	treatment	NOUN
admet-159	192	28	.	.	PUNCT
admet-159	193	1	data	datum	NOUN
admet-159	193	2	represent	represent	VERB
admet-159	193	3	mean	mean	PROPN
admet-159	193	4	±	±	NUM
admet-159	193	5	sd	sd	NOUN
admet-159	193	6	.	.	PUNCT
admet-159	194	1	n	n	NOUN
admet-159	195	1	=	=	NOUN
admet-159	195	2	12	12	NUM
admet-159	195	3	-	-	SYM
admet-159	195	4	20	20	NUM
admet-159	195	5	.	.	PUNCT
admet-159	196	1	*	*	PUNCT
admet-159	196	2	*	*	PUNCT
admet-159	196	3	:	:	PUNCT
admet-159	196	4	p<0.01	p<0.01	ADP
admet-159	196	5	as	as	SCONJ
admet-159	196	6	compared	compare	VERB
admet-159	196	7	to	to	ADP
admet-159	196	8	control	control	NOUN
admet-159	196	9	.	.	PUNCT
admet-159	197	1	green	green	ADJ
admet-159	197	2	(	(	PUNCT
admet-159	197	3	a	a	PROPN
admet-159	197	4	-	-	PUNCT
admet-159	197	5	syn	syn	NOUN
admet-159	197	6	)	)	PUNCT
admet-159	197	7	monochro./	monochro./	PROPN
admet-159	197	8	dic	dic	PROPN
admet-159	197	9	merge	merge	PROPN
admet-159	197	10	control	control	NOUN
admet-159	197	11	50	50	NUM
admet-159	197	12	μm	μm	NOUN
admet-159	197	13	cu	cu	NOUN
admet-159	198	1	100	100	NUM
admet-159	198	2	μm	μm	NUM
admet-159	198	3	cu	cu	PROPN
admet-159	198	4	a	a	NOUN
admet-159	198	5	)	)	PUNCT
admet-159	198	6	b	b	NOUN
admet-159	198	7	)	)	PUNCT
admet-159	198	8	#	#	SYM
admet-159	198	9	#	#	NOUN
admet-159	198	10	bates	bate	NOUN
admet-159	198	11	et	et	PROPN
admet-159	198	12	al	al	PROPN
admet-159	198	13	.	.	PROPN
admet-159	198	14	admet	admet	PROPN
admet-159	198	15	&	&	CCONJ
admet-159	198	16	dmpk	dmpk	PROPN
admet-159	198	17	3(1	3(1	NUM
admet-159	198	18	)	)	PUNCT
admet-159	198	19	(	(	PUNCT
admet-159	198	20	2015	2015	NUM
admet-159	198	21	)	)	PUNCT
admet-159	198	22	15	15	NUM
admet-159	198	23	-	-	SYM
admet-159	198	24	33	33	NUM
admet-159	198	25	24	24	NUM
admet-159	198	26	figure	figure	NOUN
admet-159	198	27	4	4	NUM
admet-159	198	28	.	.	PUNCT
admet-159	198	29	thioflavin	thioflavin	PROPN
admet-159	198	30	-	-	PUNCT
admet-159	198	31	t	t	PROPN
admet-159	198	32	assay	assay	NOUN
admet-159	198	33	of	of	ADP
admet-159	198	34	a	a	DET
admet-159	198	35	-	-	PUNCT
admet-159	198	36	syn	syn	NOUN
admet-159	198	37	aggregation	aggregation	NOUN
admet-159	198	38	in	in	ADP
admet-159	198	39	vitro	vitro	X
admet-159	198	40	.	.	PUNCT
admet-159	199	1	human	human	ADJ
admet-159	199	2	recombinant	recombinant	NOUN
admet-159	199	3	a	a	PROPN
admet-159	199	4	-	-	PUNCT
admet-159	199	5	syn	syn	NOUN
admet-159	199	6	was	be	AUX
admet-159	199	7	incubated	incubate	VERB
admet-159	199	8	in	in	ADP
admet-159	199	9	vitro	vitro	NOUN
admet-159	199	10	with	with	ADP
admet-159	199	11	100	100	NUM
admet-159	199	12	μm	μm	NUM
admet-159	199	13	mncl2	mncl2	NOUN
admet-159	199	14	,	,	PUNCT
admet-159	199	15	100	100	NUM
admet-159	199	16	μm	μm	NUM
admet-159	199	17	cucl2	cucl2	NOUN
admet-159	199	18	,	,	PUNCT
admet-159	199	19	or	or	CCONJ
admet-159	199	20	a	a	DET
admet-159	199	21	combination	combination	NOUN
admet-159	199	22	of	of	ADP
admet-159	199	23	100	100	NUM
admet-159	199	24	μm	μm	NUM
admet-159	199	25	mn	mn	PROPN
admet-159	199	26	and	and	CCONJ
admet-159	199	27	100	100	NUM
admet-159	199	28	µm	µm	ADP
admet-159	199	29	cu	cu	NOUN
admet-159	199	30	for	for	ADP
admet-159	199	31	72	72	NUM
admet-159	199	32	hours	hour	NOUN
admet-159	199	33	under	under	ADP
admet-159	199	34	constant	constant	ADJ
admet-159	199	35	stirring	stirring	NOUN
admet-159	199	36	with	with	ADP
admet-159	199	37	teflon	teflon	NOUN
admet-159	199	38	ball	ball	NOUN
admet-159	199	39	.	.	PUNCT
admet-159	200	1	data	datum	NOUN
admet-159	200	2	were	be	AUX
admet-159	200	3	normalized	normalize	VERB
admet-159	200	4	to	to	ADP
admet-159	200	5	the	the	DET
admet-159	200	6	maximum	maximum	ADJ
admet-159	200	7	fluorescent	fluorescent	ADJ
admet-159	200	8	values	value	NOUN
admet-159	200	9	achieved	achieve	VERB
admet-159	200	10	by	by	ADP
admet-159	200	11	each	each	DET
admet-159	200	12	group	group	NOUN
admet-159	200	13	(	(	PUNCT
admet-159	200	14	n	n	NOUN
admet-159	200	15	=	=	SYM
admet-159	200	16	3	3	NUM
admet-159	200	17	)	)	PUNCT
admet-159	200	18	.	.	PUNCT
admet-159	201	1	uptake	uptake	NOUN
admet-159	201	2	of	of	ADP
admet-159	201	3	a	a	DET
admet-159	201	4	-	-	PUNCT
admet-159	201	5	syn	syn	NOUN
admet-159	201	6	by	by	ADP
admet-159	201	7	plexus	plexus	NOUN
admet-159	201	8	cells	cell	NOUN
admet-159	201	9	and	and	CCONJ
admet-159	201	10	effect	effect	NOUN
admet-159	201	11	of	of	ADP
admet-159	201	12	mn	mn	PROPN
admet-159	201	13	exposure	exposure	NOUN
admet-159	201	14	when	when	SCONJ
admet-159	201	15	primary	primary	ADJ
admet-159	201	16	cultures	culture	NOUN
admet-159	201	17	of	of	ADP
admet-159	201	18	choroid	choroid	ADJ
admet-159	201	19	epithelial	epithelial	ADJ
admet-159	201	20	cells	cell	NOUN
admet-159	201	21	were	be	AUX
admet-159	201	22	exposed	expose	VERB
admet-159	201	23	to	to	ADP
admet-159	201	24	100	100	NUM
admet-159	201	25	μm	μm	NUM
admet-159	201	26	mncl2	mncl2	PROPN
admet-159	201	27	,	,	PUNCT
admet-159	201	28	without	without	ADP
admet-159	201	29	adding	add	VERB
admet-159	201	30	a	a	PRON
admet-159	201	31	-	-	PUNCT
admet-159	201	32	syn	syn	NOUN
admet-159	201	33	,	,	PUNCT
admet-159	201	34	the	the	DET
admet-159	201	35	cells	cell	NOUN
admet-159	201	36	displayed	display	VERB
admet-159	201	37	a	a	DET
admet-159	201	38	significant	significant	ADJ
admet-159	201	39	increase	increase	NOUN
admet-159	201	40	in	in	ADP
admet-159	201	41	a	a	DET
admet-159	201	42	-	-	PUNCT
admet-159	201	43	syn	syn	NOUN
admet-159	201	44	signals	signal	NOUN
admet-159	201	45	after	after	ADP
admet-159	201	46	48	48	NUM
admet-159	201	47	h	h	NOUN
admet-159	201	48	(	(	PUNCT
admet-159	201	49	fig	fig	NOUN
admet-159	201	50	.	.	PUNCT
admet-159	202	1	5a	5a	NUM
admet-159	202	2	)	)	PUNCT
admet-159	202	3	.	.	PUNCT
admet-159	203	1	with	with	ADP
admet-159	203	2	added	add	VERB
admet-159	203	3	external	external	ADJ
admet-159	203	4	a	a	NOUN
admet-159	203	5	-	-	PUNCT
admet-159	203	6	syn	syn	NOUN
admet-159	203	7	,	,	PUNCT
admet-159	203	8	the	the	DET
admet-159	203	9	signals	signal	NOUN
admet-159	203	10	became	become	VERB
admet-159	203	11	stronger	strong	ADJ
admet-159	203	12	and	and	CCONJ
admet-159	203	13	the	the	DET
admet-159	203	14	presence	presence	NOUN
admet-159	203	15	of	of	ADP
admet-159	203	16	intracellular	intracellular	ADJ
admet-159	203	17	puncta	puncta	NOUN
admet-159	203	18	containing	contain	VERB
admet-159	203	19	a	a	PRON
admet-159	203	20	-	-	PUNCT
admet-159	203	21	syn	syn	NOUN
admet-159	203	22	became	become	VERB
admet-159	203	23	apparent	apparent	ADJ
admet-159	203	24	(	(	PUNCT
admet-159	203	25	fig	fig	NOUN
admet-159	203	26	.	.	PUNCT
admet-159	204	1	5a	5a	NUM
admet-159	204	2	)	)	PUNCT
admet-159	204	3	.	.	PUNCT
admet-159	205	1	confocal	confocal	ADJ
admet-159	205	2	quantifications	quantification	NOUN
admet-159	205	3	revealed	reveal	VERB
admet-159	205	4	an	an	DET
admet-159	205	5	increased	increase	VERB
admet-159	205	6	signal	signal	NOUN
admet-159	205	7	intensity	intensity	NOUN
admet-159	205	8	at	at	ADP
admet-159	205	9	48	48	NUM
admet-159	205	10	h	h	NOUN
admet-159	205	11	in	in	ADP
admet-159	205	12	the	the	DET
admet-159	205	13	50	50	NUM
admet-159	205	14	μm	μm	NOUN
admet-159	205	15	group	group	NOUN
admet-159	205	16	without	without	ADP
admet-159	205	17	added	add	VERB
admet-159	205	18	a	a	DET
admet-159	205	19	-	-	PUNCT
admet-159	205	20	syn	syn	NOUN
admet-159	205	21	(	(	PUNCT
admet-159	205	22	p<0.05	p<0.05	PROPN
admet-159	205	23	)	)	PUNCT
admet-159	205	24	and	and	CCONJ
admet-159	205	25	in	in	ADP
admet-159	205	26	both	both	PRON
admet-159	205	27	50	50	NUM
admet-159	205	28	and	and	CCONJ
admet-159	205	29	100	100	NUM
admet-159	205	30	μm	μm	NUM
admet-159	205	31	groups	group	NOUN
admet-159	205	32	with	with	ADP
admet-159	205	33	added	add	VERB
admet-159	205	34	a	a	DET
admet-159	205	35	-	-	PUNCT
admet-159	205	36	syn	syn	NOUN
admet-159	205	37	(	(	PUNCT
admet-159	205	38	p<0.01	p<0.01	PROPN
admet-159	205	39	)	)	PUNCT
admet-159	205	40	as	as	SCONJ
admet-159	205	41	compared	compare	VERB
admet-159	205	42	to	to	ADP
admet-159	205	43	controls	control	NOUN
admet-159	205	44	(	(	PUNCT
admet-159	205	45	fig	fig	NOUN
admet-159	205	46	.	.	PUNCT
admet-159	206	1	5b	5b	NUM
admet-159	206	2	)	)	PUNCT
admet-159	206	3	.	.	PUNCT
admet-159	207	1	the	the	DET
admet-159	207	2	a	a	PROPN
admet-159	207	3	-	-	PUNCT
admet-159	207	4	syn	syn	NOUN
admet-159	207	5	signals	signal	NOUN
admet-159	207	6	in	in	ADP
admet-159	207	7	cells	cell	NOUN
admet-159	207	8	exposed	expose	VERB
admet-159	207	9	to	to	ADP
admet-159	207	10	mn	mn	PROPN
admet-159	207	11	+	+	CCONJ
admet-159	207	12	a	a	X
admet-159	207	13	-	-	PUNCT
admet-159	207	14	syn	syn	NOUN
admet-159	207	15	were	be	AUX
admet-159	207	16	significantly	significantly	ADV
admet-159	207	17	greater	great	ADJ
admet-159	207	18	than	than	ADP
admet-159	207	19	those	those	PRON
admet-159	207	20	in	in	ADP
admet-159	207	21	cells	cell	NOUN
admet-159	207	22	exposed	expose	VERB
admet-159	207	23	to	to	ADP
admet-159	207	24	mn	mn	PROPN
admet-159	207	25	alone	alone	ADV
admet-159	207	26	at	at	ADP
admet-159	207	27	the	the	DET
admet-159	207	28	same	same	ADJ
admet-159	207	29	mn	mn	PROPN
admet-159	207	30	concentration	concentration	NOUN
admet-159	207	31	(	(	PUNCT
admet-159	207	32	supplemental	supplemental	ADJ
admet-159	207	33	fig	fig	NOUN
admet-159	207	34	.	.	PUNCT
admet-159	208	1	s2	s2	NOUN
admet-159	208	2	-	-	PUNCT
admet-159	208	3	s3	s3	NOUN
admet-159	208	4	)	)	PUNCT
admet-159	208	5	.	.	PUNCT
admet-159	209	1	to	to	PART
admet-159	209	2	directly	directly	ADV
admet-159	209	3	quantify	quantify	VERB
admet-159	209	4	the	the	DET
admet-159	209	5	effect	effect	NOUN
admet-159	209	6	of	of	ADP
admet-159	209	7	mn	mn	PROPN
admet-159	209	8	exposure	exposure	NOUN
admet-159	209	9	on	on	ADP
admet-159	209	10	a	a	DET
admet-159	209	11	-	-	PUNCT
admet-159	209	12	syn	syn	NOUN
admet-159	209	13	uptake	uptake	NOUN
admet-159	209	14	,	,	PUNCT
admet-159	209	15	we	we	PRON
admet-159	209	16	used	use	VERB
admet-159	209	17	an	an	DET
admet-159	209	18	elisa	elisa	NOUN
admet-159	209	19	method	method	NOUN
admet-159	209	20	to	to	PART
admet-159	209	21	determine	determine	VERB
admet-159	209	22	intracellular	intracellular	ADJ
admet-159	209	23	a	a	PRON
admet-159	209	24	-	-	PUNCT
admet-159	209	25	syn	syn	NOUN
admet-159	209	26	levels	level	NOUN
admet-159	209	27	with	with	ADP
admet-159	209	28	or	or	CCONJ
admet-159	209	29	without	without	ADP
admet-159	209	30	mn	mn	PROPN
admet-159	209	31	exposure	exposure	NOUN
admet-159	209	32	.	.	PUNCT
admet-159	210	1	primary	primary	ADJ
admet-159	210	2	choroidal	choroidal	ADJ
admet-159	210	3	epithelial	epithelial	ADJ
admet-159	210	4	cells	cell	NOUN
admet-159	210	5	treated	treat	VERB
admet-159	210	6	with	with	ADP
admet-159	210	7	various	various	ADJ
admet-159	210	8	concentrations	concentration	NOUN
admet-159	210	9	of	of	ADP
admet-159	210	10	mn	mn	PROPN
admet-159	210	11	for	for	ADP
admet-159	210	12	24	24	NUM
admet-159	210	13	h	h	NOUN
admet-159	210	14	followed	follow	VERB
admet-159	210	15	by	by	ADP
admet-159	210	16	incubation	incubation	NOUN
admet-159	210	17	with	with	ADP
admet-159	210	18	a	a	PRON
admet-159	210	19	-	-	PUNCT
admet-159	210	20	syn	syn	NOUN
admet-159	210	21	for	for	ADP
admet-159	210	22	an	an	DET
admet-159	210	23	additional	additional	ADJ
admet-159	210	24	2	2	NUM
admet-159	210	25	h	h	NOUN
admet-159	210	26	showed	show	VERB
admet-159	210	27	a	a	DET
admet-159	210	28	gradual	gradual	ADJ
admet-159	210	29	decrease	decrease	NOUN
admet-159	210	30	in	in	ADP
admet-159	210	31	a	a	DET
admet-159	210	32	-	-	PUNCT
admet-159	210	33	syn	syn	NOUN
admet-159	210	34	content	content	NOUN
admet-159	210	35	with	with	ADP
admet-159	210	36	an	an	DET
admet-159	210	37	increase	increase	NOUN
admet-159	210	38	in	in	ADP
admet-159	210	39	mn	mn	PROPN
admet-159	210	40	concentration	concentration	NOUN
admet-159	210	41	(	(	PUNCT
admet-159	210	42	fig	fig	NOUN
admet-159	210	43	.	.	PUNCT
admet-159	211	1	6	6	NUM
admet-159	211	2	)	)	PUNCT
admet-159	211	3	.	.	PUNCT
admet-159	212	1	a	a	DET
admet-159	212	2	significant	significant	ADJ
admet-159	212	3	decrease	decrease	NOUN
admet-159	212	4	was	be	AUX
admet-159	212	5	observed	observe	VERB
admet-159	212	6	at	at	ADP
admet-159	212	7	100	100	NUM
admet-159	212	8	μm	μm	NUM
admet-159	212	9	mn	mn	PROPN
admet-159	212	10	(	(	PUNCT
admet-159	212	11	the	the	DET
admet-159	212	12	highest	high	ADJ
admet-159	212	13	mn	mn	PROPN
admet-159	212	14	concentration	concentration	NOUN
admet-159	212	15	)	)	PUNCT
admet-159	212	16	compared	compare	VERB
admet-159	212	17	to	to	ADP
admet-159	212	18	the	the	DET
admet-159	212	19	control	control	NOUN
admet-159	212	20	(	(	PUNCT
admet-159	212	21	p<0.05	p<0.05	PROPN
admet-159	212	22	)	)	PUNCT
admet-159	212	23	(	(	PUNCT
admet-159	212	24	fig	fig	NOUN
admet-159	212	25	.	.	PUNCT
admet-159	212	26	6	6	NUM
admet-159	212	27	)	)	PUNCT
admet-159	212	28	.	.	PUNCT
admet-159	213	1	the	the	DET
admet-159	213	2	observed	observe	VERB
admet-159	213	3	decrease	decrease	NOUN
admet-159	213	4	in	in	ADP
admet-159	213	5	a	a	PRON
admet-159	213	6	-	-	PUNCT
admet-159	213	7	syn	syn	NOUN
admet-159	213	8	uptake	uptake	NOUN
admet-159	213	9	was	be	AUX
admet-159	213	10	a	a	DET
admet-159	213	11	direct	direct	ADJ
admet-159	213	12	contrast	contrast	NOUN
admet-159	213	13	to	to	ADP
admet-159	213	14	the	the	DET
admet-159	213	15	confocal	confocal	ADJ
admet-159	213	16	microscopy	microscopy	NOUN
admet-159	213	17	data	datum	NOUN
admet-159	213	18	.	.	PUNCT
admet-159	214	1	this	this	DET
admet-159	214	2	discrepancy	discrepancy	NOUN
admet-159	214	3	could	could	AUX
admet-159	214	4	be	be	AUX
admet-159	214	5	explained	explain	VERB
admet-159	214	6	by	by	ADP
admet-159	214	7	the	the	DET
admet-159	214	8	fact	fact	NOUN
admet-159	214	9	that	that	SCONJ
admet-159	214	10	the	the	DET
admet-159	214	11	antibody	antibody	NOUN
admet-159	214	12	used	use	VERB
admet-159	214	13	in	in	ADP
admet-159	214	14	the	the	DET
admet-159	214	15	elisa	elisa	NOUN
admet-159	214	16	method	method	NOUN
admet-159	214	17	was	be	AUX
admet-159	214	18	only	only	ADV
admet-159	214	19	capable	capable	ADJ
admet-159	214	20	of	of	ADP
admet-159	214	21	detecting	detect	VERB
admet-159	214	22	human	human	ADJ
admet-159	214	23	a	a	PROPN
admet-159	214	24	-	-	PUNCT
admet-159	214	25	syn	syn	NOUN
admet-159	214	26	monomers	monomer	NOUN
admet-159	214	27	but	but	CCONJ
admet-159	214	28	not	not	PART
admet-159	214	29	oligomers	oligomer	NOUN
admet-159	214	30	.	.	PUNCT
admet-159	215	1	nonetheless	nonetheless	ADV
admet-159	215	2	,	,	PUNCT
admet-159	215	3	a	a	DET
admet-159	215	4	significant	significant	ADJ
admet-159	215	5	decrease	decrease	NOUN
admet-159	215	6	of	of	ADP
admet-159	215	7	a	a	DET
admet-159	215	8	-	-	PUNCT
admet-159	215	9	syn	syn	NOUN
admet-159	215	10	monomer	monomer	NOUN
admet-159	215	11	detected	detect	VERB
admet-159	215	12	by	by	ADP
admet-159	215	13	elisa	elisa	PROPN
admet-159	215	14	,	,	PUNCT
admet-159	215	15	in	in	ADP
admet-159	215	16	fact	fact	NOUN
admet-159	215	17	,	,	PUNCT
admet-159	215	18	indirectly	indirectly	ADV
admet-159	215	19	suggested	suggest	VERB
admet-159	215	20	an	an	DET
admet-159	215	21	increase	increase	NOUN
admet-159	215	22	in	in	ADP
admet-159	215	23	aggregated	aggregate	VERB
admet-159	215	24	a	a	PRON
admet-159	215	25	-	-	PUNCT
admet-159	215	26	syn	syn	NOUN
admet-159	215	27	within	within	ADP
admet-159	215	28	the	the	DET
admet-159	215	29	cells	cell	NOUN
admet-159	215	30	.	.	PUNCT
admet-159	216	1	a	a	X
admet-159	216	2	-	-	PUNCT
admet-159	216	3	syn	syn	NOUN
admet-159	216	4	transport	transport	NOUN
admet-159	216	5	by	by	ADP
admet-159	216	6	bcsfb	bcsfb	PROPN
admet-159	216	7	monolayer	monolayer	NOUN
admet-159	216	8	in	in	ADP
admet-159	216	9	a	a	DET
admet-159	216	10	two	two	NUM
admet-159	216	11	-	-	PUNCT
admet-159	216	12	chamber	chamber	NOUN
admet-159	216	13	transwell	transwell	NOUN
admet-159	216	14	device	device	NOUN
admet-159	216	15	to	to	PART
admet-159	216	16	determine	determine	VERB
admet-159	216	17	the	the	DET
admet-159	216	18	directional	directional	ADJ
admet-159	216	19	transport	transport	NOUN
admet-159	216	20	of	of	ADP
admet-159	216	21	a	a	DET
admet-159	216	22	-	-	PUNCT
admet-159	216	23	syn	syn	NOUN
admet-159	216	24	across	across	ADP
admet-159	216	25	the	the	DET
admet-159	216	26	bcsfb	bcsfb	NOUN
admet-159	216	27	and	and	CCONJ
admet-159	216	28	the	the	DET
admet-159	216	29	effect	effect	NOUN
admet-159	216	30	of	of	ADP
admet-159	216	31	mn	mn	PROPN
admet-159	216	32	exposure	exposure	NOUN
admet-159	217	1	,	,	PUNCT
admet-159	217	2	we	we	PRON
admet-159	217	3	adapted	adapt	VERB
admet-159	217	4	a	a	DET
admet-159	217	5	two	two	NUM
admet-159	217	6	-	-	PUNCT
admet-159	217	7	chamber	chamber	NOUN
admet-159	217	8	transwell	transwell	NOUN
admet-159	217	9	transport	transport	NOUN
admet-159	217	10	model	model	NOUN
admet-159	217	11	(	(	PUNCT
admet-159	217	12	fig	fig	NOUN
admet-159	217	13	.	.	PUNCT
admet-159	218	1	s1	s1	NOUN
admet-159	218	2	,	,	PUNCT
admet-159	218	3	efflux	efflux	NOUN
admet-159	218	4	model	model	NOUN
admet-159	218	5	is	be	AUX
admet-159	218	6	shown	show	VERB
admet-159	218	7	)	)	PUNCT
admet-159	218	8	.	.	PUNCT
admet-159	219	1	one	one	NUM
admet-159	219	2	approach	approach	NOUN
admet-159	219	3	involved	involve	VERB
admet-159	219	4	adding	add	VERB
admet-159	219	5	a	a	PRON
admet-159	219	6	-	-	PUNCT
admet-159	219	7	syn	syn	NOUN
admet-159	219	8	to	to	ADP
admet-159	219	9	the	the	DET
admet-159	219	10	outer	outer	ADJ
admet-159	219	11	(	(	PUNCT
admet-159	219	12	donor	donor	NOUN
admet-159	219	13	)	)	PUNCT
admet-159	219	14	chamber	chamber	NOUN
admet-159	219	15	and	and	CCONJ
admet-159	219	16	subsequently	subsequently	ADV
admet-159	219	17	monitoring	monitor	VERB
admet-159	219	18	the	the	DET
admet-159	219	19	appearance	appearance	NOUN
admet-159	219	20	of	of	ADP
admet-159	219	21	a	a	DET
admet-159	219	22	-	-	PUNCT
admet-159	219	23	syn	syn	NOUN
admet-159	219	24	in	in	ADP
admet-159	219	25	the	the	DET
admet-159	219	26	inner	inner	ADJ
admet-159	219	27	(	(	PUNCT
admet-159	219	28	receiver	receiver	NOUN
admet-159	219	29	)	)	PUNCT
admet-159	219	30	chamber	chamber	NOUN
admet-159	219	31	to	to	PART
admet-159	219	32	model	model	VERB
admet-159	219	33	the	the	DET
admet-159	219	34	influx	influx	NOUN
admet-159	219	35	of	of	ADP
admet-159	219	36	a	a	DET
admet-159	219	37	-	-	PUNCT
admet-159	219	38	syn	syn	NOUN
admet-159	219	39	from	from	ADP
admet-159	219	40	the	the	DET
admet-159	219	41	blood	blood	NOUN
admet-159	219	42	to	to	ADP
admet-159	219	43	the	the	DET
admet-159	219	44	csf	csf	NOUN
admet-159	219	45	.	.	PUNCT
admet-159	220	1	conversely	conversely	ADV
admet-159	220	2	,	,	PUNCT
admet-159	220	3	the	the	DET
admet-159	220	4	a	a	NOUN
admet-159	220	5	-	-	PUNCT
admet-159	220	6	syn	syn	NOUN
admet-159	220	7	was	be	AUX
admet-159	220	8	added	add	VERB
admet-159	220	9	to	to	ADP
admet-159	220	10	the	the	DET
admet-159	220	11	inner	inner	ADJ
admet-159	220	12	chamber	chamber	NOUN
admet-159	220	13	and	and	CCONJ
admet-159	220	14	the	the	DET
admet-159	220	15	protein	protein	NOUN
admet-159	220	16	’s	’s	PART
admet-159	220	17	appearance	appearance	NOUN
admet-159	220	18	in	in	ADP
admet-159	220	19	the	the	DET
admet-159	220	20	outer	outer	ADJ
admet-159	220	21	chamber	chamber	NOUN
admet-159	220	22	was	be	AUX
admet-159	220	23	monitored	monitor	VERB
admet-159	220	24	to	to	PART
admet-159	220	25	model	model	VERB
admet-159	220	26	the	the	DET
admet-159	220	27	efflux	efflux	NOUN
admet-159	220	28	of	of	ADP
admet-159	220	29	a	a	DET
admet-159	220	30	-	-	PUNCT
admet-159	220	31	syn	syn	NOUN
admet-159	220	32	from	from	ADP
admet-159	220	33	the	the	DET
admet-159	220	34	csf	csf	NOUN
admet-159	220	35	to	to	ADP
admet-159	220	36	the	the	DET
admet-159	220	37	blood	blood	NOUN
admet-159	220	38	.	.	PUNCT
admet-159	221	1	asyn+mn+cu	asyn+mn+cu	PROPN
admet-159	221	2	asyn+mn	asyn+mn	PUNCT
admet-159	221	3	asyn+cu	asyn+cu	ADJ
admet-159	221	4	asyn	asyn	ADJ
admet-159	221	5	alone	alone	ADJ
admet-159	221	6	mn+cu	mn+cu	PROPN
admet-159	221	7	admet	admet	PROPN
admet-159	221	8	&	&	CCONJ
admet-159	221	9	dmpk	dmpk	PROPN
admet-159	221	10	3(1	3(1	NUM
admet-159	221	11	)	)	PUNCT
admet-159	221	12	(	(	PUNCT
admet-159	221	13	2015	2015	NUM
admet-159	221	14	)	)	PUNCT
admet-159	221	15	15	15	NUM
admet-159	221	16	-	-	SYM
admet-159	221	17	33	33	NUM
admet-159	221	18	effects	effect	NOUN
admet-159	221	19	of	of	ADP
admet-159	221	20	manganese	manganese	ADJ
admet-159	221	21	exposure	exposure	NOUN
admet-159	221	22	on	on	ADP
admet-159	221	23	expression	expression	NOUN
admet-159	221	24	and	and	CCONJ
admet-159	221	25	transport	transport	NOUN
admet-159	221	26	of	of	ADP
admet-159	221	27	-synuclein	-synuclein	PROPN
admet-159	221	28	doi	doi	NOUN
admet-159	221	29	:	:	PUNCT
admet-159	221	30	10.5599	10.5599	NUM
admet-159	221	31	/	/	SYM
admet-159	221	32	admet.3.1.159	admet.3.1.159	NUM
admet-159	221	33	25	25	NUM
admet-159	221	34	figure	figure	NOUN
admet-159	221	35	5	5	NUM
admet-159	221	36	.	.	PUNCT
admet-159	222	1	uptake	uptake	NOUN
admet-159	222	2	of	of	ADP
admet-159	222	3	a	a	DET
admet-159	222	4	-	-	PUNCT
admet-159	222	5	syn	syn	NOUN
admet-159	222	6	by	by	ADP
admet-159	222	7	primary	primary	ADJ
admet-159	222	8	choroidal	choroidal	ADJ
admet-159	222	9	epithelial	epithelial	ADJ
admet-159	222	10	cells	cell	NOUN
admet-159	222	11	in	in	ADP
admet-159	222	12	the	the	DET
admet-159	222	13	presence	presence	NOUN
admet-159	222	14	of	of	ADP
admet-159	222	15	a	a	DET
admet-159	222	16	-	-	PUNCT
admet-159	222	17	syn	syn	NOUN
admet-159	222	18	and	and	CCONJ
admet-159	222	19	after	after	ADP
admet-159	222	20	mn	mn	PROPN
admet-159	222	21	exposure	exposure	NOUN
admet-159	222	22	.	.	PUNCT
admet-159	223	1	(	(	PUNCT
admet-159	223	2	a	a	X
admet-159	223	3	)	)	PUNCT
admet-159	223	4	ihc	ihc	PROPN
admet-159	223	5	staining	staining	NOUN
admet-159	223	6	of	of	ADP
admet-159	223	7	a	a	DET
admet-159	223	8	-	-	PUNCT
admet-159	223	9	syn	syn	NOUN
admet-159	223	10	in	in	ADP
admet-159	223	11	primary	primary	ADJ
admet-159	223	12	plexus	plexus	NOUN
admet-159	223	13	cells	cell	NOUN
admet-159	223	14	.	.	PUNCT
admet-159	224	1	cells	cell	NOUN
admet-159	224	2	were	be	AUX
admet-159	224	3	treated	treat	VERB
admet-159	224	4	with	with	ADP
admet-159	224	5	mn	mn	PROPN
admet-159	224	6	or	or	CCONJ
admet-159	224	7	saline	saline	NOUN
admet-159	224	8	(	(	PUNCT
admet-159	224	9	control	control	NOUN
admet-159	224	10	)	)	PUNCT
admet-159	224	11	for	for	ADP
admet-159	224	12	12	12	NUM
admet-159	224	13	,	,	PUNCT
admet-159	224	14	24	24	NUM
admet-159	224	15	,	,	PUNCT
admet-159	224	16	or	or	CCONJ
admet-159	224	17	48	48	NUM
admet-159	224	18	h	h	NOUN
admet-159	224	19	,	,	PUNCT
admet-159	224	20	followed	follow	VERB
admet-159	224	21	by	by	ADP
admet-159	224	22	incubation	incubation	NOUN
admet-159	224	23	with	with	ADP
admet-159	224	24	0.5	0.5	NUM
admet-159	224	25	μm	μm	NOUN
admet-159	224	26	recombinant	recombinant	ADJ
admet-159	224	27	human	human	ADJ
admet-159	224	28	a	a	NOUN
admet-159	224	29	-	-	PUNCT
admet-159	224	30	syn	syn	NOUN
admet-159	224	31	for	for	ADP
admet-159	224	32	2	2	NUM
admet-159	224	33	h.	h.	NOUN
admet-159	224	34	cells	cell	NOUN
admet-159	224	35	were	be	AUX
admet-159	224	36	stained	stain	VERB
admet-159	224	37	with	with	ADP
admet-159	224	38	primary	primary	ADJ
admet-159	224	39	anti	anti	ADJ
admet-159	224	40	-	-	ADJ
admet-159	224	41	a	a	DET
admet-159	224	42	-	-	PUNCT
admet-159	224	43	syn	syn	NOUN
admet-159	224	44	.	.	PUNCT
admet-159	225	1	a	a	DET
admet-159	225	2	typical	typical	ADJ
admet-159	225	3	study	study	NOUN
admet-159	225	4	of	of	ADP
admet-159	225	5	n	n	NOUN
admet-159	225	6	=	=	SYM
admet-159	225	7	5	5	NUM
admet-159	225	8	is	be	AUX
admet-159	225	9	presented	present	VERB
admet-159	225	10	.	.	PUNCT
admet-159	226	1	(	(	PUNCT
admet-159	226	2	b	b	X
admet-159	226	3	)	)	PUNCT
admet-159	226	4	confocal	confocal	ADJ
admet-159	226	5	quantification	quantification	NOUN
admet-159	226	6	of	of	ADP
admet-159	226	7	a	a	DET
admet-159	226	8	-	-	PUNCT
admet-159	226	9	syn	syn	NOUN
admet-159	226	10	.	.	PUNCT
admet-159	227	1	“	"	PUNCT
admet-159	227	2	+	+	PROPN
admet-159	227	3	mn	mn	PROPN
admet-159	227	4	,	,	PUNCT
admet-159	227	5	-a	-a	PROPN
admet-159	227	6	-	-	PUNCT
admet-159	227	7	syn	syn	NOUN
admet-159	227	8	”	"	PUNCT
admet-159	227	9	:	:	PUNCT
admet-159	227	10	cells	cell	NOUN
admet-159	227	11	treated	treat	VERB
admet-159	227	12	with	with	ADP
admet-159	227	13	mn	mn	PROPN
admet-159	227	14	but	but	CCONJ
admet-159	227	15	without	without	ADP
admet-159	227	16	added	add	VERB
admet-159	227	17	a	a	PRON
admet-159	227	18	-	-	PUNCT
admet-159	227	19	syn	syn	NOUN
admet-159	227	20	;	;	PUNCT
admet-159	227	21	“	"	PUNCT
admet-159	227	22	+	+	PROPN
admet-159	227	23	mn	mn	PROPN
admet-159	227	24	,	,	PUNCT
admet-159	227	25	+	+	NOUN
admet-159	227	26	a	a	X
admet-159	227	27	-	-	PUNCT
admet-159	227	28	syn	syn	NOUN
admet-159	227	29	”	"	PUNCT
admet-159	227	30	:	:	PUNCT
admet-159	227	31	cells	cell	NOUN
admet-159	227	32	treated	treat	VERB
admet-159	227	33	with	with	ADP
admet-159	227	34	mn	mn	PROPN
admet-159	227	35	followed	follow	VERB
admet-159	227	36	by	by	ADP
admet-159	227	37	a	a	DET
admet-159	227	38	-	-	PUNCT
admet-159	227	39	syn	syn	NOUN
admet-159	227	40	incubation	incubation	NOUN
admet-159	227	41	.	.	PUNCT
admet-159	228	1	data	datum	NOUN
admet-159	228	2	represent	represent	VERB
admet-159	228	3	mean	mean	PROPN
admet-159	228	4	±	±	NUM
admet-159	228	5	sd	sd	NOUN
admet-159	228	6	.	.	PUNCT
admet-159	229	1	n	n	NOUN
admet-159	230	1	=	=	SYM
admet-159	230	2	10	10	NUM
admet-159	230	3	-	-	SYM
admet-159	230	4	24	24	NUM
admet-159	230	5	.	.	PUNCT
admet-159	231	1	*	*	PUNCT
admet-159	231	2	:	:	PUNCT
admet-159	231	3	p	p	X
admet-159	231	4	<	<	X
admet-159	231	5	0.05	0.05	NUM
admet-159	231	6	,	,	PUNCT
admet-159	231	7	*	*	PUNCT
admet-159	231	8	*	*	PUNCT
admet-159	231	9	:	:	PUNCT
admet-159	231	10	p	p	X
admet-159	231	11	<	<	X
admet-159	231	12	0.01	0.01	NUM
admet-159	231	13	,	,	PUNCT
admet-159	231	14	*	*	PUNCT
admet-159	231	15	*	*	PUNCT
admet-159	231	16	*	*	PUNCT
admet-159	231	17	:	:	PUNCT
admet-159	231	18	p	p	X
admet-159	231	19	<	<	X
admet-159	231	20	0.001	0.001	NUM
admet-159	231	21	as	as	SCONJ
admet-159	231	22	compared	compare	VERB
admet-159	231	23	to	to	ADP
admet-159	231	24	controls	control	NOUN
admet-159	231	25	at	at	ADP
admet-159	231	26	matching	match	VERB
admet-159	231	27	time	time	NOUN
admet-159	231	28	point	point	NOUN
admet-159	231	29	.	.	PUNCT
admet-159	232	1	results	result	NOUN
admet-159	232	2	from	from	ADP
admet-159	232	3	the	the	DET
admet-159	232	4	influx	influx	NOUN
admet-159	232	5	study	study	NOUN
admet-159	232	6	showed	show	VERB
admet-159	232	7	that	that	SCONJ
admet-159	232	8	after	after	SCONJ
admet-159	232	9	a	a	PROPN
admet-159	232	10	-	-	PUNCT
admet-159	232	11	syn	syn	NOUN
admet-159	232	12	was	be	AUX
admet-159	232	13	added	add	VERB
admet-159	232	14	to	to	ADP
admet-159	232	15	the	the	DET
admet-159	232	16	outer	outer	ADJ
admet-159	232	17	chamber	chamber	NOUN
admet-159	232	18	,	,	PUNCT
admet-159	232	19	there	there	PRON
admet-159	232	20	was	be	VERB
admet-159	232	21	a	a	DET
admet-159	232	22	significant	significant	ADJ
admet-159	232	23	increase	increase	NOUN
admet-159	232	24	of	of	ADP
admet-159	232	25	a	a	DET
admet-159	232	26	-	-	PUNCT
admet-159	232	27	syn	syn	NOUN
admet-159	232	28	content	content	NOUN
admet-159	232	29	in	in	ADP
admet-159	232	30	the	the	DET
admet-159	232	31	inner	inner	ADJ
admet-159	232	32	chamber	chamber	NOUN
admet-159	232	33	between	between	ADP
admet-159	232	34	the	the	DET
admet-159	232	35	0	0	NUM
admet-159	232	36	-	-	PUNCT
admet-159	232	37	h	h	NOUN
admet-159	232	38	and	and	CCONJ
admet-159	232	39	6	6	NUM
admet-159	232	40	-	-	PUNCT
admet-159	232	41	h	h	NOUN
admet-159	232	42	time	time	NOUN
admet-159	232	43	points	point	NOUN
admet-159	232	44	;	;	PUNCT
admet-159	232	45	the	the	DET
admet-159	232	46	increase	increase	NOUN
admet-159	232	47	continued	continue	VERB
admet-159	232	48	until	until	ADP
admet-159	232	49	12	12	NUM
admet-159	232	50	-	-	PUNCT
admet-159	232	51	h	h	NOUN
admet-159	232	52	in	in	ADP
admet-159	232	53	the	the	DET
admet-159	232	54	inner	inner	ADJ
admet-159	232	55	chamber	chamber	NOUN
admet-159	232	56	,	,	PUNCT
admet-159	232	57	followed	follow	VERB
admet-159	232	58	by	by	ADP
admet-159	232	59	a	a	DET
admet-159	232	60	gradual	gradual	ADJ
admet-159	232	61	decline	decline	NOUN
admet-159	232	62	at	at	ADP
admet-159	232	63	24	24	NUM
admet-159	232	64	-	-	PUNCT
admet-159	232	65	h	h	NOUN
admet-159	232	66	(	(	PUNCT
admet-159	232	67	fig	fig	NOUN
admet-159	232	68	.	.	PUNCT
admet-159	233	1	7a	7a	NUM
admet-159	233	2	)	)	PUNCT
admet-159	233	3	.	.	PUNCT
admet-159	234	1	accordingly	accordingly	ADV
admet-159	234	2	,	,	PUNCT
admet-159	234	3	the	the	DET
admet-159	234	4	a	a	PROPN
admet-159	234	5	-	-	PUNCT
admet-159	234	6	syn	syn	NOUN
admet-159	234	7	concentration	concentration	NOUN
admet-159	234	8	in	in	ADP
admet-159	234	9	the	the	DET
admet-159	234	10	outer	outer	ADJ
admet-159	234	11	(	(	PUNCT
admet-159	234	12	donor	donor	NOUN
admet-159	234	13	)	)	PUNCT
admet-159	234	14	chamber	chamber	NOUN
admet-159	234	15	decreased	decrease	VERB
admet-159	234	16	significantly	significantly	ADV
admet-159	234	17	between	between	ADP
admet-159	234	18	the	the	DET
admet-159	234	19	0	0	NUM
admet-159	234	20	-	-	PUNCT
admet-159	234	21	h	h	NOUN
admet-159	234	22	and	and	CCONJ
admet-159	234	23	6	6	NUM
admet-159	234	24	-	-	PUNCT
admet-159	234	25	h	h	NOUN
admet-159	234	26	time	time	NOUN
admet-159	234	27	points	point	NOUN
admet-159	234	28	.	.	PUNCT
admet-159	235	1	interestingly	interestingly	ADV
admet-159	235	2	,	,	PUNCT
admet-159	235	3	the	the	DET
admet-159	235	4	a	a	PROPN
admet-159	235	5	-	-	PUNCT
admet-159	235	6	syn	syn	NOUN
admet-159	235	7	concentration	concentration	NOUN
admet-159	235	8	in	in	ADP
admet-159	235	9	the	the	DET
admet-159	235	10	outer	outer	ADJ
admet-159	235	11	chamber	chamber	NOUN
admet-159	235	12	began	begin	VERB
admet-159	235	13	to	to	PART
admet-159	235	14	increase	increase	VERB
admet-159	235	15	to	to	ADP
admet-159	235	16	an	an	DET
admet-159	235	17	apparent	apparent	ADJ
admet-159	235	18	steady	steady	ADJ
admet-159	235	19	state	state	NOUN
admet-159	235	20	between	between	ADP
admet-159	235	21	12	12	NUM
admet-159	235	22	and	and	CCONJ
admet-159	235	23	24	24	NUM
admet-159	235	24	h	h	NOUN
admet-159	235	25	(	(	PUNCT
admet-159	235	26	fig	fig	NOUN
admet-159	235	27	.	.	PUNCT
admet-159	236	1	7a	7a	NUM
admet-159	236	2	)	)	PUNCT
admet-159	236	3	.	.	PUNCT
admet-159	237	1	mn	mn	PROPN
admet-159	237	2	exposure	exposure	NOUN
admet-159	237	3	had	have	VERB
admet-159	237	4	no	no	DET
admet-159	237	5	significant	significant	ADJ
admet-159	237	6	effect	effect	NOUN
admet-159	237	7	on	on	ADP
admet-159	237	8	a	a	DET
admet-159	237	9	-	-	PUNCT
admet-159	237	10	syn	syn	NOUN
admet-159	237	11	concentrations	concentration	NOUN
admet-159	237	12	in	in	ADP
admet-159	237	13	either	either	CCONJ
admet-159	237	14	the	the	DET
admet-159	237	15	inner	inner	ADJ
admet-159	237	16	or	or	CCONJ
admet-159	237	17	outer	outer	ADJ
admet-159	237	18	chambers	chamber	NOUN
admet-159	237	19	at	at	ADP
admet-159	237	20	any	any	DET
admet-159	237	21	given	give	VERB
admet-159	237	22	time	time	NOUN
admet-159	237	23	point	point	NOUN
admet-159	237	24	(	(	PUNCT
admet-159	237	25	fig	fig	NOUN
admet-159	237	26	.	.	PUNCT
admet-159	237	27	7a	7a	NUM
admet-159	237	28	)	)	PUNCT
admet-159	237	29	.	.	PUNCT
admet-159	238	1	by	by	ADP
admet-159	238	2	quantifying	quantify	VERB
admet-159	238	3	a	a	PROPN
admet-159	238	4	-	-	PUNCT
admet-159	238	5	syn	syn	NOUN
admet-159	238	6	concentrations	concentration	NOUN
admet-159	238	7	in	in	ADP
admet-159	238	8	choroidal	choroidal	ADJ
admet-159	238	9	epithelial	epithelial	ADJ
admet-159	238	10	cells	cell	NOUN
admet-159	238	11	,	,	PUNCT
admet-159	238	12	we	we	PRON
admet-159	238	13	determined	determine	VERB
admet-159	238	14	that	that	SCONJ
admet-159	238	15	there	there	PRON
admet-159	238	16	was	be	VERB
admet-159	238	17	a	a	DET
admet-159	238	18	detectable	detectable	ADJ
admet-159	238	19	amount	amount	NOUN
admet-159	238	20	of	of	ADP
admet-159	238	21	a	a	DET
admet-159	238	22	-	-	PUNCT
admet-159	238	23	syn	syn	NOUN
admet-159	238	24	accumulated	accumulate	VERB
admet-159	238	25	in	in	ADP
admet-159	238	26	the	the	DET
admet-159	238	27	cells	cell	NOUN
admet-159	238	28	in	in	ADP
admet-159	238	29	the	the	DET
admet-159	238	30	control	control	NOUN
admet-159	238	31	group	group	NOUN
admet-159	238	32	,	,	PUNCT
admet-159	238	33	and	and	CCONJ
admet-159	238	34	this	this	DET
admet-159	238	35	accumulation	accumulation	NOUN
admet-159	238	36	appeared	appear	VERB
admet-159	238	37	to	to	PART
admet-159	238	38	continue	continue	VERB
admet-159	238	39	to	to	PART
admet-159	238	40	increase	increase	VERB
admet-159	238	41	up	up	ADP
admet-159	238	42	to	to	PART
admet-159	238	43	24	24	NUM
admet-159	238	44	h	h	NOUN
admet-159	238	45	,	,	PUNCT
admet-159	238	46	although	although	SCONJ
admet-159	238	47	there	there	PRON
admet-159	238	48	was	be	VERB
admet-159	238	49	no	no	DET
admet-159	238	50	statistical	statistical	ADJ
admet-159	238	51	significance	significance	NOUN
admet-159	238	52	between	between	ADP
admet-159	238	53	12	12	NUM
admet-159	238	54	and	and	CCONJ
admet-159	238	55	24	24	NUM
admet-159	238	56	h	h	NOUN
admet-159	238	57	(	(	PUNCT
admet-159	238	58	fig	fig	NOUN
admet-159	238	59	.	.	PUNCT
admet-159	239	1	7b	7b	NOUN
admet-159	239	2	)	)	PUNCT
admet-159	239	3	.	.	PUNCT
admet-159	240	1	mn	mn	PROPN
admet-159	240	2	treatment	treatment	NOUN
admet-159	240	3	had	have	VERB
admet-159	240	4	no	no	DET
admet-159	240	5	significant	significant	ADJ
admet-159	240	6	effect	effect	NOUN
admet-159	240	7	on	on	ADP
admet-159	240	8	intracellular	intracellular	ADJ
admet-159	240	9	a	a	PRON
admet-159	240	10	-	-	PUNCT
admet-159	240	11	syn	syn	NOUN
admet-159	240	12	concentrations	concentration	NOUN
admet-159	240	13	of	of	ADP
admet-159	240	14	the	the	DET
admet-159	240	15	choroidal	choroidal	ADJ
admet-159	240	16	epithelial	epithelial	ADJ
admet-159	240	17	monolayer	monolayer	NOUN
admet-159	240	18	(	(	PUNCT
admet-159	240	19	fig	fig	NOUN
admet-159	240	20	.	.	PUNCT
admet-159	241	1	7b	7b	NOUN
admet-159	241	2	)	)	PUNCT
admet-159	241	3	.	.	PUNCT
admet-159	242	1	a	a	DET
admet-159	242	2	)	)	PUNCT
admet-159	242	3	b	b	NOUN
admet-159	242	4	)	)	PUNCT
admet-159	242	5	*	*	PUNCT
admet-159	243	1	*	*	PUNCT
admet-159	243	2	*	*	PUNCT
admet-159	243	3	*	*	PUNCT
admet-159	244	1	*	*	PUNCT
admet-159	244	2	*	*	PUNCT
admet-159	244	3	*	*	PUNCT
admet-159	244	4	*	*	PUNCT
admet-159	244	5	*	*	PUNCT
admet-159	244	6	*	*	PUNCT
admet-159	244	7	*	*	PUNCT
admet-159	244	8	*	*	PUNCT
admet-159	244	9	*	*	PUNCT
admet-159	244	10	bates	bate	NOUN
admet-159	244	11	et	et	PROPN
admet-159	244	12	al	al	PROPN
admet-159	244	13	.	.	PROPN
admet-159	244	14	admet	admet	PROPN
admet-159	244	15	&	&	CCONJ
admet-159	244	16	dmpk	dmpk	PROPN
admet-159	244	17	3(1	3(1	NUM
admet-159	244	18	)	)	PUNCT
admet-159	244	19	(	(	PUNCT
admet-159	244	20	2015	2015	NUM
admet-159	244	21	)	)	PUNCT
admet-159	244	22	15	15	NUM
admet-159	244	23	-	-	SYM
admet-159	244	24	33	33	NUM
admet-159	244	25	26	26	NUM
admet-159	244	26	figure	figure	NOUN
admet-159	244	27	6	6	NUM
admet-159	244	28	.	.	PUNCT
admet-159	244	29	elisa	elisa	VERB
admet-159	244	30	quantification	quantification	NOUN
admet-159	244	31	of	of	ADP
admet-159	244	32	a	a	DET
admet-159	244	33	-	-	PUNCT
admet-159	244	34	syn	syn	NOUN
admet-159	244	35	uptake	uptake	NOUN
admet-159	244	36	by	by	ADP
admet-159	244	37	primary	primary	ADJ
admet-159	244	38	choroidal	choroidal	ADJ
admet-159	244	39	epithelial	epithelial	ADJ
admet-159	244	40	cells	cell	NOUN
admet-159	244	41	following	follow	VERB
admet-159	244	42	mn	mn	PROPN
admet-159	244	43	exposure	exposure	NOUN
admet-159	244	44	.	.	PUNCT
admet-159	245	1	primary	primary	ADJ
admet-159	245	2	cells	cell	NOUN
admet-159	245	3	were	be	AUX
admet-159	245	4	pre	pre	VERB
admet-159	245	5	-	-	VERB
admet-159	245	6	treated	treat	VERB
admet-159	245	7	with	with	ADP
admet-159	245	8	25	25	NUM
admet-159	245	9	,	,	PUNCT
admet-159	245	10	50	50	NUM
admet-159	245	11	,	,	PUNCT
admet-159	245	12	or	or	CCONJ
admet-159	245	13	100	100	NUM
admet-159	245	14	μm	μm	NUM
admet-159	245	15	mncl2	mncl2	NOUN
admet-159	245	16	or	or	CCONJ
admet-159	245	17	with	with	ADP
admet-159	245	18	saline	saline	NOUN
admet-159	245	19	(	(	PUNCT
admet-159	245	20	‘	'	PUNCT
admet-159	245	21	ct	ct	NUM
admet-159	245	22	’	'	PUNCT
admet-159	245	23	)	)	PUNCT
admet-159	245	24	for	for	ADP
admet-159	245	25	24	24	NUM
admet-159	245	26	h	h	NOUN
admet-159	245	27	,	,	PUNCT
admet-159	245	28	followed	follow	VERB
admet-159	245	29	by	by	ADP
admet-159	245	30	incubation	incubation	NOUN
admet-159	245	31	with	with	ADP
admet-159	245	32	0.5	0.5	NUM
admet-159	245	33	mg	mg	NOUN
admet-159	245	34	/	/	SYM
admet-159	245	35	ml	ml	NOUN
admet-159	245	36	a	a	PROPN
admet-159	245	37	-	-	PUNCT
admet-159	245	38	syn	syn	NOUN
admet-159	245	39	for	for	ADP
admet-159	245	40	2	2	NUM
admet-159	245	41	h.	h.	PROPN
admet-159	245	42	nct	nct	PROPN
admet-159	245	43	(	(	PUNCT
admet-159	245	44	negative	negative	ADJ
admet-159	245	45	control	control	NOUN
admet-159	245	46	)	)	PUNCT
admet-159	245	47	was	be	AUX
admet-159	245	48	not	not	PART
admet-159	245	49	treated	treat	VERB
admet-159	245	50	with	with	ADP
admet-159	245	51	mncl2	mncl2	PROPN
admet-159	245	52	,	,	PUNCT
admet-159	245	53	saline	saline	NOUN
admet-159	245	54	,	,	PUNCT
admet-159	245	55	or	or	CCONJ
admet-159	245	56	a	a	DET
admet-159	245	57	-	-	PUNCT
admet-159	245	58	syn	syn	NOUN
admet-159	245	59	.	.	PUNCT
admet-159	246	1	levels	level	NOUN
admet-159	246	2	of	of	ADP
admet-159	246	3	a	a	PRON
admet-159	246	4	-	-	PUNCT
admet-159	246	5	syn	syn	NOUN
admet-159	246	6	were	be	AUX
admet-159	246	7	quantified	quantify	VERB
admet-159	246	8	by	by	ADP
admet-159	246	9	elisa	elisa	PROPN
admet-159	246	10	.	.	PUNCT
admet-159	247	1	data	datum	NOUN
admet-159	247	2	represent	represent	VERB
admet-159	247	3	mean	mean	PROPN
admet-159	247	4	±	±	NUM
admet-159	247	5	sd	sd	NOUN
admet-159	247	6	,	,	PUNCT
admet-159	247	7	n	n	NOUN
admet-159	247	8	=	=	SYM
admet-159	247	9	5	5	NUM
admet-159	247	10	.	.	PUNCT
admet-159	248	1	*	*	ADJ
admet-159	248	2	:	:	PUNCT
admet-159	248	3	p<0.05	p<0.05	NOUN
admet-159	248	4	,	,	PUNCT
admet-159	248	5	*	*	PUNCT
admet-159	248	6	*	*	PUNCT
admet-159	248	7	:	:	PUNCT
admet-159	248	8	p<0.01	p<0.01	PRON
admet-159	248	9	as	as	SCONJ
admet-159	248	10	compared	compare	VERB
admet-159	248	11	with	with	ADP
admet-159	248	12	controls	control	NOUN
admet-159	248	13	.	.	PUNCT
admet-159	249	1	the	the	DET
admet-159	249	2	efflux	efflux	NOUN
admet-159	249	3	study	study	NOUN
admet-159	249	4	showed	show	VERB
admet-159	249	5	an	an	DET
admet-159	249	6	increase	increase	NOUN
admet-159	249	7	of	of	ADP
admet-159	249	8	a	a	DET
admet-159	249	9	-	-	PUNCT
admet-159	249	10	syn	syn	NOUN
admet-159	249	11	in	in	ADP
admet-159	249	12	the	the	DET
admet-159	249	13	outer	outer	ADJ
admet-159	249	14	(	(	PUNCT
admet-159	249	15	receiver	receiver	NOUN
admet-159	249	16	)	)	PUNCT
admet-159	249	17	chamber	chamber	NOUN
admet-159	249	18	from	from	ADP
admet-159	249	19	the	the	DET
admet-159	249	20	0	0	NUM
admet-159	249	21	-	-	PUNCT
admet-159	249	22	h	h	NOUN
admet-159	249	23	time	time	NOUN
admet-159	249	24	point	point	NOUN
admet-159	249	25	to	to	ADP
admet-159	249	26	the	the	DET
admet-159	249	27	12	12	NUM
admet-159	249	28	-	-	PUNCT
admet-159	249	29	h	h	NOUN
admet-159	249	30	time	time	NOUN
admet-159	249	31	point	point	NOUN
admet-159	249	32	,	,	PUNCT
admet-159	249	33	followed	follow	VERB
admet-159	249	34	by	by	ADP
admet-159	249	35	a	a	DET
admet-159	249	36	decrease	decrease	NOUN
admet-159	249	37	at	at	ADP
admet-159	249	38	24	24	NUM
admet-159	249	39	h	h	NOUN
admet-159	249	40	(	(	PUNCT
admet-159	249	41	fig	fig	NOUN
admet-159	249	42	.	.	PUNCT
admet-159	249	43	8a	8a	NUM
admet-159	249	44	)	)	PUNCT
admet-159	249	45	.	.	PUNCT
admet-159	250	1	in	in	ADP
admet-159	250	2	the	the	DET
admet-159	250	3	inner	inner	ADJ
admet-159	250	4	donor	donor	NOUN
admet-159	250	5	chamber	chamber	PROPN
admet-159	250	6	,	,	PUNCT
admet-159	250	7	the	the	DET
admet-159	250	8	a	a	PROPN
admet-159	250	9	-	-	PUNCT
admet-159	250	10	syn	syn	NOUN
admet-159	250	11	levels	level	NOUN
admet-159	250	12	were	be	AUX
admet-159	250	13	initially	initially	ADV
admet-159	250	14	sharply	sharply	ADV
admet-159	250	15	decreased	decrease	VERB
admet-159	250	16	between	between	ADP
admet-159	250	17	the	the	DET
admet-159	250	18	0	0	NUM
admet-159	250	19	-	-	PUNCT
admet-159	250	20	h	h	NOUN
admet-159	250	21	and	and	CCONJ
admet-159	250	22	6	6	NUM
admet-159	250	23	-	-	PUNCT
admet-159	250	24	h	h	NOUN
admet-159	250	25	time	time	NOUN
admet-159	250	26	points	point	NOUN
admet-159	250	27	,	,	PUNCT
admet-159	250	28	followed	follow	VERB
admet-159	250	29	by	by	ADP
admet-159	250	30	a	a	DET
admet-159	250	31	significant	significant	ADJ
admet-159	250	32	,	,	PUNCT
admet-159	250	33	albeit	albeit	SCONJ
admet-159	250	34	slight	slight	ADJ
admet-159	250	35	,	,	PUNCT
admet-159	250	36	increase	increase	VERB
admet-159	250	37	in	in	ADP
admet-159	250	38	a	a	DET
admet-159	250	39	-	-	PUNCT
admet-159	250	40	syn	syn	NOUN
admet-159	250	41	content	content	NOUN
admet-159	250	42	between	between	ADP
admet-159	250	43	the	the	DET
admet-159	250	44	6	6	NUM
admet-159	250	45	-	-	PUNCT
admet-159	250	46	h	h	NOUN
admet-159	250	47	and	and	CCONJ
admet-159	250	48	12	12	NUM
admet-159	250	49	-	-	PUNCT
admet-159	250	50	h	h	NOUN
admet-159	250	51	time	time	NOUN
admet-159	250	52	points	point	NOUN
admet-159	250	53	(	(	PUNCT
admet-159	250	54	fig	fig	NOUN
admet-159	250	55	.	.	PUNCT
admet-159	251	1	8a	8a	NUM
admet-159	251	2	)	)	PUNCT
admet-159	251	3	.	.	PUNCT
admet-159	252	1	the	the	DET
admet-159	252	2	a	a	PROPN
admet-159	252	3	-	-	PUNCT
admet-159	252	4	syn	syn	NOUN
admet-159	252	5	concentration	concentration	NOUN
admet-159	252	6	in	in	ADP
admet-159	252	7	the	the	DET
admet-159	252	8	inner	inner	ADJ
admet-159	252	9	chamber	chamber	NOUN
admet-159	252	10	appeared	appear	VERB
admet-159	252	11	to	to	PART
admet-159	252	12	reach	reach	VERB
admet-159	252	13	a	a	DET
admet-159	252	14	steady	steady	ADJ
admet-159	252	15	state	state	NOUN
admet-159	252	16	between	between	ADP
admet-159	252	17	12and	12and	NOUN
admet-159	252	18	24	24	NUM
admet-159	252	19	-	-	PUNCT
admet-159	252	20	h	h	NOUN
admet-159	252	21	time	time	NOUN
admet-159	252	22	points	point	NOUN
admet-159	252	23	(	(	PUNCT
admet-159	252	24	fig	fig	NOUN
admet-159	252	25	.	.	PUNCT
admet-159	253	1	8a	8a	NUM
admet-159	253	2	)	)	PUNCT
admet-159	253	3	.	.	PUNCT
admet-159	254	1	similar	similar	ADJ
admet-159	254	2	to	to	ADP
admet-159	254	3	the	the	DET
admet-159	254	4	influx	influx	NOUN
admet-159	254	5	study	study	NOUN
admet-159	254	6	,	,	PUNCT
admet-159	254	7	mn	mn	PROPN
admet-159	254	8	exposure	exposure	NOUN
admet-159	254	9	had	have	VERB
admet-159	254	10	no	no	DET
admet-159	254	11	significant	significant	ADJ
admet-159	254	12	effect	effect	NOUN
admet-159	254	13	on	on	ADP
admet-159	254	14	the	the	DET
admet-159	254	15	transport	transport	NOUN
admet-159	254	16	of	of	ADP
admet-159	254	17	a	a	DET
admet-159	254	18	-	-	PUNCT
admet-159	254	19	syn	syn	NOUN
admet-159	254	20	by	by	ADP
admet-159	254	21	the	the	DET
admet-159	254	22	bcsfb	bcsfb	PROPN
admet-159	254	23	monolayer	monolayer	NOUN
admet-159	254	24	(	(	PUNCT
admet-159	254	25	fig	fig	NOUN
admet-159	254	26	.	.	PUNCT
admet-159	255	1	8a	8a	NUM
admet-159	255	2	)	)	PUNCT
admet-159	255	3	.	.	PUNCT
admet-159	256	1	also	also	ADV
admet-159	256	2	similar	similar	ADJ
admet-159	256	3	to	to	ADP
admet-159	256	4	the	the	DET
admet-159	256	5	influx	influx	NOUN
admet-159	256	6	study	study	NOUN
admet-159	256	7	,	,	PUNCT
admet-159	256	8	the	the	DET
admet-159	256	9	accumulation	accumulation	NOUN
admet-159	256	10	of	of	ADP
admet-159	256	11	a	a	DET
admet-159	256	12	-	-	PUNCT
admet-159	256	13	syn	syn	NOUN
admet-159	256	14	in	in	ADP
admet-159	256	15	primary	primary	ADJ
admet-159	256	16	choroidal	choroidal	ADJ
admet-159	256	17	epithelial	epithelial	ADJ
admet-159	256	18	cells	cell	NOUN
admet-159	256	19	in	in	ADP
admet-159	256	20	controls	control	NOUN
admet-159	256	21	was	be	AUX
admet-159	256	22	increased	increase	VERB
admet-159	256	23	from	from	ADP
admet-159	256	24	0	0	NUM
admet-159	256	25	-	-	PUNCT
admet-159	256	26	h	h	NOUN
admet-159	256	27	to	to	ADP
admet-159	256	28	24	24	NUM
admet-159	256	29	h	h	NOUN
admet-159	256	30	,	,	PUNCT
admet-159	256	31	although	although	SCONJ
admet-159	256	32	there	there	PRON
admet-159	256	33	was	be	VERB
admet-159	256	34	no	no	DET
admet-159	256	35	significant	significant	ADJ
admet-159	256	36	change	change	NOUN
admet-159	256	37	between	between	ADP
admet-159	256	38	12	12	NUM
admet-159	256	39	and	and	CCONJ
admet-159	256	40	24	24	NUM
admet-159	256	41	h	h	NOUN
admet-159	256	42	(	(	PUNCT
admet-159	256	43	fig	fig	NOUN
admet-159	256	44	.	.	PUNCT
admet-159	257	1	8b	8b	NUM
admet-159	257	2	)	)	PUNCT
admet-159	257	3	.	.	PUNCT
admet-159	258	1	mn	mn	PROPN
admet-159	258	2	exposure	exposure	NOUN
admet-159	258	3	did	do	AUX
admet-159	258	4	not	not	PART
admet-159	258	5	significantly	significantly	ADV
admet-159	258	6	alter	alter	VERB
admet-159	258	7	the	the	DET
admet-159	258	8	intracellular	intracellular	ADJ
admet-159	258	9	a	a	PRON
admet-159	258	10	-	-	PUNCT
admet-159	258	11	syn	syn	NOUN
admet-159	258	12	concentrations	concentration	NOUN
admet-159	258	13	of	of	ADP
admet-159	258	14	the	the	DET
admet-159	258	15	bcsfb	bcsfb	PROPN
admet-159	258	16	monolayer	monolayer	NOUN
admet-159	258	17	(	(	PUNCT
admet-159	258	18	fig	fig	NOUN
admet-159	258	19	.	.	PUNCT
admet-159	258	20	8b	8b	NUM
admet-159	258	21	)	)	PUNCT
admet-159	258	22	.	.	PUNCT
admet-159	259	1	the	the	DET
admet-159	259	2	results	result	NOUN
admet-159	259	3	from	from	ADP
admet-159	259	4	these	these	DET
admet-159	259	5	influx	influx	NOUN
admet-159	259	6	/	/	SYM
admet-159	259	7	efflux	efflux	NOUN
admet-159	259	8	studies	study	NOUN
admet-159	259	9	suggested	suggest	VERB
admet-159	259	10	that	that	SCONJ
admet-159	259	11	a	a	X
admet-159	259	12	-	-	PUNCT
admet-159	259	13	syn	syn	NOUN
admet-159	259	14	molecules	molecule	NOUN
admet-159	259	15	were	be	AUX
admet-159	259	16	likely	likely	ADV
admet-159	259	17	transported	transport	VERB
admet-159	259	18	in	in	ADP
admet-159	259	19	either	either	DET
admet-159	259	20	direction	direction	NOUN
admet-159	259	21	across	across	ADP
admet-159	259	22	the	the	DET
admet-159	259	23	bcsfb	bcsfb	NOUN
admet-159	259	24	monolayer	monolayer	NOUN
admet-159	259	25	,	,	PUNCT
admet-159	259	26	and	and	CCONJ
admet-159	259	27	the	the	DET
admet-159	259	28	bcsfb	bcsfb	NOUN
admet-159	259	29	did	do	AUX
admet-159	259	30	not	not	PART
admet-159	259	31	appear	appear	VERB
admet-159	259	32	to	to	PART
admet-159	259	33	have	have	VERB
admet-159	259	34	a	a	DET
admet-159	259	35	preferred	preferred	ADJ
admet-159	259	36	direction	direction	NOUN
admet-159	259	37	of	of	ADP
admet-159	259	38	a	a	DET
admet-159	259	39	-	-	PUNCT
admet-159	259	40	syn	syn	NOUN
admet-159	259	41	transport	transport	NOUN
admet-159	259	42	.	.	PUNCT
admet-159	260	1	moreover	moreover	ADV
admet-159	260	2	,	,	PUNCT
admet-159	260	3	mn	mn	PROPN
admet-159	260	4	exposure	exposure	NOUN
admet-159	260	5	had	have	VERB
admet-159	260	6	no	no	DET
admet-159	260	7	effect	effect	NOUN
admet-159	260	8	on	on	ADP
admet-159	260	9	a	a	DET
admet-159	260	10	-	-	PUNCT
admet-159	260	11	syn	syn	NOUN
admet-159	260	12	transport	transport	NOUN
admet-159	260	13	by	by	ADP
admet-159	260	14	the	the	DET
admet-159	260	15	bcsfb	bcsfb	NOUN
admet-159	260	16	or	or	CCONJ
admet-159	260	17	intracellular	intracellular	ADJ
admet-159	260	18	a	a	PRON
admet-159	260	19	-	-	PUNCT
admet-159	260	20	syn	syn	NOUN
admet-159	260	21	content	content	NOUN
admet-159	260	22	.	.	PUNCT
admet-159	261	1	discussion	discussion	NOUN
admet-159	261	2	the	the	DET
admet-159	261	3	data	datum	NOUN
admet-159	261	4	presented	present	VERB
admet-159	261	5	in	in	ADP
admet-159	261	6	this	this	DET
admet-159	261	7	report	report	NOUN
admet-159	261	8	suggest	suggest	VERB
admet-159	261	9	that	that	SCONJ
admet-159	261	10	1	1	X
admet-159	261	11	)	)	PUNCT
admet-159	261	12	a	a	PRON
admet-159	261	13	-	-	PUNCT
admet-159	261	14	syn	syn	NOUN
admet-159	261	15	is	be	AUX
admet-159	261	16	naturally	naturally	ADV
admet-159	261	17	expressed	express	VERB
admet-159	261	18	in	in	ADP
admet-159	261	19	choroid	choroid	NOUN
admet-159	261	20	plexus	plexus	NOUN
admet-159	261	21	tissues	tissue	NOUN
admet-159	261	22	,	,	PUNCT
admet-159	261	23	particularly	particularly	ADV
admet-159	261	24	within	within	ADP
admet-159	261	25	epithelial	epithelial	ADJ
admet-159	261	26	cells	cell	NOUN
admet-159	261	27	;	;	PUNCT
admet-159	261	28	it	it	PRON
admet-159	261	29	is	be	AUX
admet-159	261	30	also	also	ADV
admet-159	261	31	present	present	ADJ
admet-159	261	32	in	in	ADP
admet-159	261	33	the	the	DET
admet-159	261	34	immortalized	immortalized	ADJ
admet-159	261	35	choroidal	choroidal	ADJ
admet-159	261	36	epithelial	epithelial	ADJ
admet-159	261	37	z310	z310	PROPN
admet-159	261	38	cell	cell	NOUN
admet-159	261	39	line	line	NOUN
admet-159	261	40	;	;	PUNCT
admet-159	261	41	2	2	X
admet-159	261	42	)	)	PUNCT
admet-159	261	43	treatment	treatment	NOUN
admet-159	261	44	of	of	ADP
admet-159	261	45	plexus	plexus	NOUN
admet-159	261	46	cells	cell	NOUN
admet-159	261	47	with	with	ADP
admet-159	261	48	mn	mn	PROPN
admet-159	261	49	or	or	CCONJ
admet-159	261	50	cu	cu	PROPN
admet-159	261	51	induces	induce	VERB
admet-159	261	52	a	a	DET
admet-159	261	53	-	-	PUNCT
admet-159	261	54	syn	syn	NOUN
admet-159	261	55	accumulation	accumulation	NOUN
admet-159	261	56	within	within	ADP
admet-159	261	57	the	the	DET
admet-159	261	58	bcb	bcb	NOUN
admet-159	261	59	;	;	PUNCT
admet-159	261	60	3	3	X
admet-159	261	61	)	)	PUNCT
admet-159	261	62	mn	mn	NOUN
admet-159	261	63	exposure	exposure	NOUN
admet-159	261	64	does	do	AUX
admet-159	261	65	not	not	PART
admet-159	261	66	significantly	significantly	ADV
admet-159	261	67	alter	alter	VERB
admet-159	261	68	a	a	DET
admet-159	261	69	-	-	PUNCT
admet-159	261	70	syn	syn	NOUN
admet-159	261	71	production	production	NOUN
admet-159	261	72	at	at	ADP
admet-159	261	73	the	the	DET
admet-159	261	74	transcriptional	transcriptional	ADJ
admet-159	261	75	level	level	NOUN
admet-159	261	76	;	;	PUNCT
admet-159	261	77	4	4	X
admet-159	261	78	)	)	PUNCT
admet-159	261	79	in	in	ADP
admet-159	261	80	the	the	DET
admet-159	261	81	test	test	NOUN
admet-159	261	82	tube	tube	NOUN
admet-159	261	83	,	,	PUNCT
admet-159	261	84	incubation	incubation	NOUN
admet-159	261	85	of	of	ADP
admet-159	261	86	a	a	DET
admet-159	261	87	-	-	PUNCT
admet-159	261	88	syn	syn	NOUN
admet-159	261	89	with	with	ADP
admet-159	261	90	mn	mn	PROPN
admet-159	261	91	or	or	CCONJ
admet-159	261	92	cu	cu	PROPN
admet-159	261	93	causes	cause	VERB
admet-159	261	94	the	the	DET
admet-159	261	95	aggregation	aggregation	NOUN
admet-159	261	96	of	of	ADP
admet-159	261	97	a	a	DET
admet-159	261	98	-	-	PUNCT
admet-159	261	99	syn	syn	NOUN
admet-159	261	100	;	;	PUNCT
admet-159	261	101	and	and	CCONJ
admet-159	261	102	5	5	X
admet-159	261	103	)	)	PUNCT
admet-159	261	104	while	while	SCONJ
admet-159	261	105	mn	mn	PROPN
admet-159	261	106	exposure	exposure	NOUN
admet-159	261	107	does	do	AUX
admet-159	261	108	not	not	PART
admet-159	261	109	affect	affect	VERB
admet-159	261	110	the	the	DET
admet-159	261	111	transport	transport	NOUN
admet-159	261	112	of	of	ADP
admet-159	261	113	a	a	DET
admet-159	261	114	-	-	PUNCT
admet-159	261	115	syn	syn	NOUN
admet-159	261	116	across	across	ADP
admet-159	261	117	the	the	DET
admet-159	261	118	bcsfb	bcsfb	PROPN
admet-159	261	119	monolayer	monolayer	NOUN
admet-159	261	120	,	,	PUNCT
admet-159	261	121	it	it	PRON
admet-159	261	122	increases	increase	VERB
admet-159	261	123	a	a	DET
admet-159	261	124	-	-	PUNCT
admet-159	261	125	syn	syn	NOUN
admet-159	261	126	uptake	uptake	NOUN
admet-159	261	127	by	by	ADP
admet-159	261	128	a	a	DET
admet-159	261	129	primary	primary	ADJ
admet-159	261	130	culture	culture	NOUN
admet-159	261	131	of	of	ADP
admet-159	261	132	choroidal	choroidal	ADJ
admet-159	261	133	epithelial	epithelial	ADJ
admet-159	261	134	cells	cell	NOUN
admet-159	261	135	.	.	PUNCT
admet-159	262	1	*	*	PUNCT
admet-159	262	2	*	*	PUNCT
admet-159	262	3	*	*	PUNCT
admet-159	262	4	admet	admet	PROPN
admet-159	262	5	&	&	CCONJ
admet-159	262	6	dmpk	dmpk	PROPN
admet-159	262	7	3(1	3(1	NUM
admet-159	262	8	)	)	PUNCT
admet-159	262	9	(	(	PUNCT
admet-159	262	10	2015	2015	NUM
admet-159	262	11	)	)	PUNCT
admet-159	262	12	15	15	NUM
admet-159	262	13	-	-	SYM
admet-159	262	14	33	33	NUM
admet-159	262	15	effects	effect	NOUN
admet-159	262	16	of	of	ADP
admet-159	262	17	manganese	manganese	ADJ
admet-159	262	18	exposure	exposure	NOUN
admet-159	262	19	on	on	ADP
admet-159	262	20	expression	expression	NOUN
admet-159	262	21	and	and	CCONJ
admet-159	262	22	transport	transport	NOUN
admet-159	262	23	of	of	ADP
admet-159	262	24	-synuclein	-synuclein	PROPN
admet-159	262	25	doi	doi	NOUN
admet-159	262	26	:	:	PUNCT
admet-159	262	27	10.5599	10.5599	NUM
admet-159	262	28	/	/	SYM
admet-159	262	29	admet.3.1.159	admet.3.1.159	NUM
admet-159	262	30	27	27	NUM
admet-159	262	31	figure	figure	NOUN
admet-159	262	32	7	7	NUM
admet-159	262	33	.	.	PUNCT
admet-159	262	34	effect	effect	NOUN
admet-159	262	35	of	of	ADP
admet-159	262	36	mn	mn	PROPN
admet-159	262	37	exposure	exposure	NOUN
admet-159	262	38	on	on	ADP
admet-159	262	39	a	a	DET
admet-159	262	40	-	-	PUNCT
admet-159	262	41	syn	syn	NOUN
admet-159	262	42	influx	influx	NOUN
admet-159	262	43	transport	transport	NOUN
admet-159	262	44	(	(	PUNCT
admet-159	262	45	from	from	ADP
admet-159	262	46	the	the	DET
admet-159	262	47	outer	outer	NOUN
admet-159	262	48	to	to	ADP
admet-159	262	49	inner	inner	ADJ
admet-159	262	50	chamber	chamber	NOUN
admet-159	262	51	)	)	PUNCT
admet-159	262	52	by	by	ADP
admet-159	262	53	choroidal	choroidal	ADJ
admet-159	262	54	epithelial	epithelial	ADJ
admet-159	262	55	monolayer	monolayer	NOUN
admet-159	262	56	.	.	PUNCT
admet-159	263	1	primary	primary	ADJ
admet-159	263	2	choroidal	choroidal	ADJ
admet-159	263	3	cells	cell	NOUN
admet-159	263	4	were	be	AUX
admet-159	263	5	cultured	cultured	ADJ
admet-159	263	6	in	in	ADP
admet-159	263	7	the	the	DET
admet-159	263	8	inner	inner	ADJ
admet-159	263	9	chamber	chamber	NOUN
admet-159	263	10	.	.	PUNCT
admet-159	264	1	an	an	DET
admet-159	264	2	aliquot	aliquot	NOUN
admet-159	264	3	of	of	ADP
admet-159	264	4	a	a	PRON
admet-159	264	5	-	-	PUNCT
admet-159	264	6	syn	syn	NOUN
admet-159	264	7	was	be	AUX
admet-159	264	8	added	add	VERB
admet-159	264	9	to	to	ADP
admet-159	264	10	the	the	DET
admet-159	264	11	outer	outer	ADJ
admet-159	264	12	chamber	chamber	NOUN
admet-159	264	13	after	after	SCONJ
admet-159	264	14	the	the	DET
admet-159	264	15	cells	cell	NOUN
admet-159	264	16	were	be	AUX
admet-159	264	17	treated	treat	VERB
admet-159	264	18	with	with	ADP
admet-159	264	19	100	100	NUM
admet-159	264	20	μm	μm	NUM
admet-159	264	21	mncl2	mncl2	NOUN
admet-159	264	22	for	for	ADP
admet-159	264	23	24	24	NUM
admet-159	264	24	h.	h.	PROPN
admet-159	264	25	levels	level	NOUN
admet-159	264	26	of	of	ADP
admet-159	264	27	a	a	DET
admet-159	264	28	-	-	PUNCT
admet-159	264	29	syn	syn	NOUN
admet-159	264	30	in	in	ADP
admet-159	264	31	both	both	DET
admet-159	264	32	chambers	chamber	NOUN
admet-159	264	33	and	and	CCONJ
admet-159	264	34	in	in	ADP
admet-159	264	35	the	the	DET
admet-159	264	36	cells	cell	NOUN
admet-159	264	37	were	be	AUX
admet-159	264	38	quantified	quantify	VERB
admet-159	264	39	by	by	ADP
admet-159	264	40	elisa	elisa	PROPN
admet-159	264	41	.	.	PUNCT
admet-159	265	1	(	(	PUNCT
admet-159	265	2	a	a	X
admet-159	265	3	)	)	PUNCT
admet-159	265	4	time	time	NOUN
admet-159	265	5	course	course	NOUN
admet-159	265	6	.	.	PUNCT
admet-159	266	1	data	datum	NOUN
admet-159	266	2	represent	represent	VERB
admet-159	266	3	mean	mean	PROPN
admet-159	266	4	±	±	NUM
admet-159	266	5	sd	sd	NOUN
admet-159	266	6	,	,	PUNCT
admet-159	266	7	n	n	NOUN
admet-159	266	8	=	=	SYM
admet-159	266	9	6	6	NUM
admet-159	266	10	.	.	PUNCT
admet-159	266	11	means	mean	NOUN
admet-159	266	12	are	be	AUX
admet-159	266	13	compared	compare	VERB
admet-159	266	14	between	between	ADP
admet-159	266	15	inner	inner	ADJ
admet-159	266	16	and	and	CCONJ
admet-159	266	17	outer	outer	ADJ
admet-159	266	18	chamber	chamber	NOUN
admet-159	266	19	at	at	ADP
admet-159	266	20	each	each	DET
admet-159	266	21	time	time	NOUN
admet-159	266	22	point	point	NOUN
admet-159	266	23	(	(	PUNCT
admet-159	266	24	6	6	NUM
admet-159	266	25	,	,	PUNCT
admet-159	266	26	12	12	NUM
admet-159	266	27	,	,	PUNCT
admet-159	266	28	24	24	NUM
admet-159	266	29	h	h	NOUN
admet-159	266	30	)	)	PUNCT
admet-159	266	31	.	.	PUNCT
admet-159	267	1	*	*	PUNCT
admet-159	267	2	*	*	PUNCT
admet-159	267	3	*	*	PUNCT
admet-159	267	4	:	:	PUNCT
admet-159	267	5	p	p	X
admet-159	267	6	<	<	X
admet-159	267	7	0.001	0.001	NUM
admet-159	267	8	as	as	SCONJ
admet-159	267	9	compared	compare	VERB
admet-159	267	10	to	to	ADP
admet-159	267	11	6	6	NUM
admet-159	267	12	-	-	PUNCT
admet-159	267	13	hour	hour	NOUN
admet-159	267	14	inner	inner	ADJ
admet-159	267	15	chamber	chamber	PROPN
admet-159	267	16	/	/	SYM
admet-159	267	17	ct	ct	PROPN
admet-159	267	18	group	group	NOUN
admet-159	267	19	.	.	PUNCT
admet-159	268	1	#	#	SYM
admet-159	268	2	#	#	SYM
admet-159	268	3	#	#	NOUN
admet-159	268	4	:	:	PUNCT
admet-159	268	5	p	p	X
admet-159	268	6	<	<	X
admet-159	268	7	0.001	0.001	NUM
admet-159	268	8	as	as	SCONJ
admet-159	268	9	compared	compare	VERB
admet-159	268	10	to	to	ADP
admet-159	268	11	6	6	NUM
admet-159	268	12	-	-	PUNCT
admet-159	268	13	hour	hour	NOUN
admet-159	268	14	outer	outer	ADJ
admet-159	268	15	chamber	chamber	PROPN
admet-159	268	16	/	/	SYM
admet-159	268	17	ct	ct	PROPN
admet-159	268	18	group	group	NOUN
admet-159	268	19	.	.	PUNCT
admet-159	269	1	(	(	PUNCT
admet-159	269	2	b	b	X
admet-159	269	3	)	)	PUNCT
admet-159	269	4	a	a	DET
admet-159	269	5	-	-	PUNCT
admet-159	269	6	syn	syn	NOUN
admet-159	269	7	concentrations	concentration	NOUN
admet-159	269	8	in	in	ADP
admet-159	269	9	cell	cell	NOUN
admet-159	269	10	monolayer	monolayer	NOUN
admet-159	269	11	following	follow	VERB
admet-159	269	12	mn	mn	PROPN
admet-159	269	13	exposure	exposure	NOUN
admet-159	269	14	.	.	PUNCT
admet-159	270	1	data	datum	NOUN
admet-159	270	2	represent	represent	VERB
admet-159	270	3	mean	mean	PROPN
admet-159	270	4	±	±	NUM
admet-159	270	5	s.d	s.d	PROPN
admet-159	270	6	.	.	PROPN
admet-159	270	7	,	,	PUNCT
admet-159	270	8	n	n	NOUN
admet-159	270	9	=	=	SYM
admet-159	270	10	5	5	NUM
admet-159	270	11	-	-	SYM
admet-159	270	12	6	6	NUM
admet-159	270	13	.	.	PUNCT
admet-159	270	14	figure	figure	NOUN
admet-159	270	15	8	8	NUM
admet-159	270	16	.	.	PUNCT
admet-159	271	1	effect	effect	NOUN
admet-159	271	2	of	of	ADP
admet-159	271	3	mn	mn	PROPN
admet-159	271	4	exposure	exposure	NOUN
admet-159	271	5	on	on	ADP
admet-159	271	6	a	a	DET
admet-159	271	7	-	-	PUNCT
admet-159	271	8	syn	syn	NOUN
admet-159	271	9	efflux	efflux	NOUN
admet-159	271	10	transport	transport	NOUN
admet-159	271	11	(	(	PUNCT
admet-159	271	12	from	from	ADP
admet-159	271	13	the	the	DET
admet-159	271	14	inner	inner	NOUN
admet-159	271	15	to	to	ADP
admet-159	271	16	outer	outer	ADJ
admet-159	271	17	chamber	chamber	NOUN
admet-159	271	18	)	)	PUNCT
admet-159	271	19	by	by	ADP
admet-159	271	20	choroidal	choroidal	ADJ
admet-159	271	21	epithelial	epithelial	ADJ
admet-159	271	22	monolayer	monolayer	NOUN
admet-159	271	23	.	.	PUNCT
admet-159	272	1	primary	primary	ADJ
admet-159	272	2	choroidal	choroidal	ADJ
admet-159	272	3	cells	cell	NOUN
admet-159	272	4	were	be	AUX
admet-159	272	5	cultured	cultured	ADJ
admet-159	272	6	in	in	ADP
admet-159	272	7	the	the	DET
admet-159	272	8	inner	inner	ADJ
admet-159	272	9	chamber	chamber	NOUN
admet-159	272	10	.	.	PUNCT
admet-159	273	1	an	an	DET
admet-159	273	2	aliquot	aliquot	NOUN
admet-159	273	3	of	of	ADP
admet-159	273	4	a	a	PRON
admet-159	273	5	-	-	PUNCT
admet-159	273	6	syn	syn	NOUN
admet-159	273	7	was	be	AUX
admet-159	273	8	added	add	VERB
admet-159	273	9	to	to	ADP
admet-159	273	10	the	the	DET
admet-159	273	11	inner	inner	ADJ
admet-159	273	12	chamber	chamber	NOUN
admet-159	273	13	after	after	SCONJ
admet-159	273	14	the	the	DET
admet-159	273	15	cells	cell	NOUN
admet-159	273	16	were	be	AUX
admet-159	273	17	treated	treat	VERB
admet-159	273	18	with	with	ADP
admet-159	273	19	50	50	NUM
admet-159	273	20	μm	μm	NOUN
admet-159	273	21	mncl2	mncl2	NOUN
admet-159	273	22	for	for	ADP
admet-159	273	23	24	24	NUM
admet-159	273	24	h.	h.	PROPN
admet-159	273	25	levels	level	NOUN
admet-159	273	26	of	of	ADP
admet-159	273	27	a	a	DET
admet-159	273	28	-	-	PUNCT
admet-159	273	29	syn	syn	NOUN
admet-159	273	30	in	in	ADP
admet-159	273	31	both	both	DET
admet-159	273	32	chambers	chamber	NOUN
admet-159	273	33	and	and	CCONJ
admet-159	273	34	in	in	ADP
admet-159	273	35	the	the	DET
admet-159	273	36	cells	cell	NOUN
admet-159	273	37	were	be	AUX
admet-159	273	38	quantified	quantify	VERB
admet-159	273	39	by	by	ADP
admet-159	273	40	elisa	elisa	PROPN
admet-159	273	41	.	.	PUNCT
admet-159	274	1	(	(	PUNCT
admet-159	274	2	a	a	X
admet-159	274	3	)	)	PUNCT
admet-159	274	4	time	time	NOUN
admet-159	274	5	course	course	NOUN
admet-159	274	6	.	.	PUNCT
admet-159	275	1	data	datum	NOUN
admet-159	275	2	represent	represent	VERB
admet-159	275	3	mean	mean	PROPN
admet-159	275	4	±	±	NUM
admet-159	275	5	sd	sd	NOUN
admet-159	275	6	.	.	PUNCT
admet-159	276	1	n	n	NOUN
admet-159	276	2	=	=	SYM
admet-159	276	3	6	6	NUM
admet-159	276	4	.	.	PUNCT
admet-159	276	5	means	mean	NOUN
admet-159	276	6	were	be	AUX
admet-159	276	7	compared	compare	VERB
admet-159	276	8	between	between	ADP
admet-159	276	9	inner	inner	ADJ
admet-159	276	10	and	and	CCONJ
admet-159	276	11	outer	outer	ADJ
admet-159	276	12	chamber	chamber	NOUN
admet-159	276	13	at	at	ADP
admet-159	276	14	each	each	DET
admet-159	276	15	time	time	NOUN
admet-159	276	16	point	point	NOUN
admet-159	276	17	(	(	PUNCT
admet-159	276	18	6	6	NUM
admet-159	276	19	,	,	PUNCT
admet-159	276	20	12	12	NUM
admet-159	276	21	,	,	PUNCT
admet-159	276	22	24	24	NUM
admet-159	276	23	h	h	NOUN
admet-159	276	24	)	)	PUNCT
admet-159	276	25	.	.	PUNCT
admet-159	277	1	*	*	PUNCT
admet-159	277	2	*	*	PUNCT
admet-159	277	3	*	*	PUNCT
admet-159	277	4	:	:	PUNCT
admet-159	277	5	p	p	X
admet-159	277	6	<	<	X
admet-159	277	7	0.001	0.001	NUM
admet-159	277	8	as	as	SCONJ
admet-159	277	9	compared	compare	VERB
admet-159	277	10	to	to	ADP
admet-159	277	11	6	6	NUM
admet-159	277	12	-	-	PUNCT
admet-159	277	13	hour	hour	NOUN
admet-159	277	14	inner	inner	ADJ
admet-159	277	15	chamber	chamber	PROPN
admet-159	277	16	/	/	SYM
admet-159	277	17	ct	ct	PROPN
admet-159	277	18	group	group	NOUN
admet-159	277	19	#	#	SYM
admet-159	277	20	#	#	SYM
admet-159	277	21	#	#	NOUN
admet-159	277	22	:	:	PUNCT
admet-159	277	23	p	p	X
admet-159	277	24	<	<	X
admet-159	277	25	0.001	0.001	NUM
admet-159	277	26	as	as	SCONJ
admet-159	277	27	compared	compare	VERB
admet-159	277	28	to	to	ADP
admet-159	277	29	6	6	NUM
admet-159	277	30	-	-	PUNCT
admet-159	277	31	hour	hour	NOUN
admet-159	277	32	outer	outer	ADJ
admet-159	277	33	chamber	chamber	PROPN
admet-159	277	34	/	/	SYM
admet-159	277	35	ct	ct	PROPN
admet-159	277	36	group	group	NOUN
admet-159	277	37	.	.	PUNCT
admet-159	278	1	(	(	PUNCT
admet-159	278	2	b	b	X
admet-159	278	3	)	)	PUNCT
admet-159	278	4	a	a	DET
admet-159	278	5	-	-	PUNCT
admet-159	278	6	syn	syn	NOUN
admet-159	278	7	concentrations	concentration	NOUN
admet-159	278	8	in	in	ADP
admet-159	278	9	cell	cell	NOUN
admet-159	278	10	monolayer	monolayer	NOUN
admet-159	278	11	following	follow	VERB
admet-159	278	12	mn	mn	PROPN
admet-159	278	13	exposure	exposure	NOUN
admet-159	278	14	.	.	PUNCT
admet-159	279	1	data	datum	NOUN
admet-159	279	2	represent	represent	VERB
admet-159	279	3	mean	mean	PROPN
admet-159	279	4	±	±	NUM
admet-159	279	5	s.d	s.d	PROPN
admet-159	279	6	.	.	PROPN
admet-159	279	7	,	,	PUNCT
admet-159	279	8	n	n	NOUN
admet-159	279	9	=	=	SYM
admet-159	279	10	5	5	NUM
admet-159	279	11	-	-	SYM
admet-159	279	12	6	6	NUM
admet-159	279	13	.	.	PUNCT
admet-159	279	14	endogenous	endogenous	ADJ
admet-159	279	15	expression	expression	NOUN
admet-159	279	16	of	of	ADP
admet-159	279	17	a	a	PRON
admet-159	279	18	-	-	PUNCT
admet-159	279	19	syn	syn	NOUN
admet-159	279	20	occurs	occur	VERB
admet-159	279	21	across	across	ADP
admet-159	279	22	a	a	DET
admet-159	279	23	variety	variety	NOUN
admet-159	279	24	of	of	ADP
admet-159	279	25	cell	cell	NOUN
admet-159	279	26	types	type	NOUN
admet-159	279	27	,	,	PUNCT
admet-159	279	28	e.g.	e.g.	ADV
admet-159	279	29	neurons	neuron	NOUN
admet-159	279	30	,	,	PUNCT
admet-159	279	31	erythrocytes	erythrocyte	NOUN
admet-159	279	32	,	,	PUNCT
admet-159	279	33	etc	etc	X
admet-159	279	34	.	.	PUNCT
admet-159	280	1	[	[	X
admet-159	280	2	52,53	52,53	NOUN
admet-159	280	3	]	]	PUNCT
admet-159	280	4	.	.	PUNCT
admet-159	281	1	here	here	ADV
admet-159	281	2	we	we	PRON
admet-159	281	3	report	report	VERB
admet-159	281	4	the	the	DET
admet-159	281	5	expression	expression	NOUN
admet-159	281	6	of	of	ADP
admet-159	281	7	endogenous	endogenous	ADJ
admet-159	281	8	a	a	PRON
admet-159	281	9	-	-	PUNCT
admet-159	281	10	syn	syn	NOUN
admet-159	281	11	in	in	ADP
admet-159	281	12	choroidal	choroidal	ADJ
admet-159	281	13	epithelial	epithelial	ADJ
admet-159	281	14	cells	cell	NOUN
admet-159	281	15	in	in	ADP
admet-159	281	16	brain	brain	NOUN
admet-159	281	17	ventricles	ventricle	NOUN
admet-159	281	18	.	.	PUNCT
admet-159	282	1	multiple	multiple	ADJ
admet-159	282	2	functions	function	NOUN
admet-159	282	3	have	have	AUX
admet-159	282	4	been	be	AUX
admet-159	282	5	proposed	propose	VERB
admet-159	282	6	for	for	ADP
admet-159	282	7	a	a	DET
admet-159	282	8	-	-	PUNCT
admet-159	282	9	syn	syn	NOUN
admet-159	282	10	in	in	ADP
admet-159	282	11	neurons	neuron	NOUN
admet-159	282	12	[	[	X
admet-159	282	13	54	54	NUM
admet-159	282	14	]	]	PUNCT
admet-159	282	15	;	;	PUNCT
admet-159	282	16	but	but	CCONJ
admet-159	282	17	how	how	SCONJ
admet-159	282	18	endogenous	endogenous	ADJ
admet-159	282	19	a	a	PRON
admet-159	282	20	-	-	PUNCT
admet-159	282	21	syn	syn	NOUN
admet-159	282	22	may	may	AUX
admet-159	282	23	function	function	VERB
admet-159	282	24	in	in	ADP
admet-159	282	25	a	a	DET
admet-159	282	26	cell	cell	NOUN
admet-159	282	27	type	type	NOUN
admet-159	282	28	constituting	constitute	VERB
admet-159	282	29	a	a	DET
admet-159	282	30	cellular	cellular	ADJ
admet-159	282	31	barrier	barrier	NOUN
admet-159	282	32	between	between	ADP
admet-159	282	33	blood	blood	NOUN
admet-159	282	34	and	and	CCONJ
admet-159	282	35	csf	csf	NOUN
admet-159	282	36	remains	remain	VERB
admet-159	282	37	unknown	unknown	ADJ
admet-159	282	38	.	.	PUNCT
admet-159	283	1	interestingly	interestingly	ADV
admet-159	283	2	,	,	PUNCT
admet-159	283	3	exposure	exposure	NOUN
admet-159	283	4	of	of	ADP
admet-159	283	5	these	these	DET
admet-159	283	6	barrier	barrier	NOUN
admet-159	283	7	cells	cell	NOUN
admet-159	283	8	to	to	ADP
admet-159	283	9	mn	mn	PROPN
admet-159	283	10	can	can	AUX
admet-159	283	11	lead	lead	VERB
admet-159	283	12	to	to	AUX
admet-159	283	13	increased	increase	VERB
admet-159	283	14	a	a	DET
admet-159	283	15	-	-	PUNCT
admet-159	283	16	syn	syn	NOUN
admet-159	283	17	fluorescent	fluorescent	NOUN
admet-159	283	18	signals	signal	NOUN
admet-159	283	19	within	within	ADP
admet-159	283	20	these	these	DET
admet-159	283	21	cells	cell	NOUN
admet-159	283	22	.	.	PUNCT
admet-159	284	1	generally	generally	ADV
admet-159	284	2	,	,	PUNCT
admet-159	284	3	intracellular	intracellular	ADJ
admet-159	284	4	protein	protein	NOUN
admet-159	284	5	levels	level	NOUN
admet-159	284	6	increase	increase	VERB
admet-159	284	7	as	as	ADP
admet-159	284	8	a	a	DET
admet-159	284	9	result	result	NOUN
admet-159	284	10	of	of	ADP
admet-159	284	11	(	(	PUNCT
admet-159	284	12	1	1	X
admet-159	284	13	)	)	PUNCT
admet-159	284	14	increased	increase	VERB
admet-159	284	15	protein	protein	NOUN
admet-159	284	16	de	de	NOUN
admet-159	284	17	-	-	ADJ
admet-159	284	18	novo	novo	ADJ
admet-159	284	19	synthesis	synthesis	NOUN
admet-159	284	20	,	,	PUNCT
admet-159	284	21	(	(	PUNCT
admet-159	284	22	2	2	X
admet-159	284	23	)	)	PUNCT
admet-159	284	24	decreased	decrease	VERB
admet-159	284	25	protein	protein	NOUN
admet-159	284	26	degradation	degradation	NOUN
admet-159	284	27	,	,	PUNCT
admet-159	284	28	and/or	and/or	CCONJ
admet-159	284	29	(	(	PUNCT
admet-159	284	30	3	3	X
admet-159	284	31	)	)	PUNCT
admet-159	284	32	an	an	DET
admet-159	284	33	altered	alter	VERB
admet-159	284	34	protein	protein	NOUN
admet-159	284	35	transport	transport	NOUN
admet-159	284	36	mechanism	mechanism	NOUN
admet-159	284	37	.	.	PUNCT
admet-159	285	1	our	our	PRON
admet-159	285	2	qpcr	qpcr	ADJ
admet-159	285	3	study	study	NOUN
admet-159	285	4	clearly	clearly	ADV
admet-159	285	5	showed	show	VERB
admet-159	285	6	that	that	SCONJ
admet-159	285	7	the	the	DET
admet-159	285	8	levels	level	NOUN
admet-159	285	9	of	of	ADP
admet-159	285	10	mrnas	mrna	NOUN
admet-159	285	11	encoding	encode	VERB
admet-159	285	12	a	a	PROPN
admet-159	285	13	-	-	PUNCT
admet-159	285	14	syn	syn	NOUN
admet-159	285	15	were	be	AUX
admet-159	285	16	not	not	PART
admet-159	285	17	affected	affect	VERB
admet-159	285	18	by	by	ADP
admet-159	285	19	mn	mn	PROPN
admet-159	285	20	exposure	exposure	NOUN
admet-159	285	21	in	in	ADP
admet-159	285	22	the	the	DET
admet-159	285	23	choroidal	choroidal	ADJ
admet-159	285	24	z310	z310	PROPN
admet-159	285	25	cells	cell	NOUN
admet-159	285	26	.	.	PUNCT
admet-159	286	1	while	while	SCONJ
admet-159	286	2	this	this	DET
admet-159	286	3	observation	observation	NOUN
admet-159	286	4	conflicts	conflict	NOUN
admet-159	286	5	with	with	ADP
admet-159	286	6	previous	previous	ADJ
admet-159	286	7	reports	report	NOUN
admet-159	286	8	,	,	PUNCT
admet-159	286	9	which	which	PRON
admet-159	286	10	show	show	VERB
admet-159	286	11	increased	increase	VERB
admet-159	286	12	a	a	PRON
admet-159	286	13	-	-	PUNCT
admet-159	286	14	syn	syn	NOUN
admet-159	286	15	expression	expression	NOUN
admet-159	286	16	following	follow	VERB
admet-159	286	17	mn	mn	PROPN
admet-159	286	18	exposure	exposure	NOUN
admet-159	286	19	in	in	ADP
admet-159	286	20	neurons	neuron	NOUN
admet-159	286	21	and	and	CCONJ
admet-159	286	22	pc12	pc12	PROPN
admet-159	286	23	cells	cell	NOUN
admet-159	286	24	[	[	X
admet-159	286	25	40,41	40,41	NOUN
admet-159	286	26	]	]	PUNCT
admet-159	286	27	,	,	PUNCT
admet-159	286	28	it	it	PRON
admet-159	286	29	is	be	AUX
admet-159	286	30	possible	possible	ADJ
admet-159	286	31	that	that	SCONJ
admet-159	286	32	different	different	ADJ
admet-159	286	33	cell	cell	NOUN
admet-159	286	34	types	type	NOUN
admet-159	286	35	have	have	VERB
admet-159	286	36	entirely	entirely	ADV
admet-159	286	37	different	different	ADJ
admet-159	286	38	responses	response	NOUN
admet-159	286	39	to	to	ADP
admet-159	286	40	mn	mn	PROPN
admet-159	286	41	treatment	treatment	NOUN
admet-159	286	42	.	.	PUNCT
admet-159	287	1	in	in	ADP
admet-159	287	2	the	the	DET
admet-159	287	3	current	current	ADJ
admet-159	287	4	study	study	NOUN
admet-159	287	5	,	,	PUNCT
admet-159	287	6	we	we	PRON
admet-159	287	7	did	do	AUX
admet-159	287	8	not	not	PART
admet-159	287	9	study	study	VERB
admet-159	287	10	the	the	DET
admet-159	287	11	a	a	PROPN
admet-159	287	12	-	-	PUNCT
admet-159	287	13	syn	syn	NOUN
admet-159	287	14	degradation	degradation	NOUN
admet-159	287	15	process	process	NOUN
admet-159	287	16	.	.	PUNCT
admet-159	288	1	thus	thus	ADV
admet-159	288	2	,	,	PUNCT
admet-159	288	3	it	it	PRON
admet-159	288	4	is	be	AUX
admet-159	288	5	unclear	unclear	ADJ
admet-159	288	6	whether	whether	SCONJ
admet-159	288	7	mn	mn	PROPN
admet-159	288	8	treatment	treatment	NOUN
admet-159	288	9	inhibits	inhibit	VERB
admet-159	288	10	or	or	CCONJ
admet-159	288	11	promotes	promote	VERB
admet-159	288	12	the	the	DET
admet-159	288	13	activity	activity	NOUN
admet-159	288	14	of	of	ADP
admet-159	288	15	the	the	DET
admet-159	288	16	enzyme	enzyme	NOUN
admet-159	288	17	system	system	NOUN
admet-159	288	18	a	a	NOUN
admet-159	288	19	)	)	PUNCT
admet-159	288	20	*	*	PUNCT
admet-159	289	1	*	*	PUNCT
admet-159	289	2	*	*	PUNCT
admet-159	290	1	#	#	SYM
admet-159	290	2	#	#	SYM
admet-159	290	3	#	#	NOUN
admet-159	290	4	#	#	SYM
admet-159	290	5	#	#	SYM
admet-159	290	6	#	#	NOUN
admet-159	290	7	*	*	NOUN
admet-159	290	8	*	*	PUNCT
admet-159	290	9	*	*	PUNCT
admet-159	291	1	*	*	PUNCT
admet-159	291	2	*	*	PUNCT
admet-159	291	3	*	*	PUNCT
admet-159	292	1	#	#	SYM
admet-159	292	2	#	#	SYM
admet-159	292	3	#	#	NOUN
admet-159	292	4	#	#	SYM
admet-159	292	5	#	#	NOUN
admet-159	292	6	#	#	NOUN
admet-159	292	7	bates	bate	NOUN
admet-159	292	8	et	et	PROPN
admet-159	292	9	al	al	PROPN
admet-159	292	10	.	.	PROPN
admet-159	292	11	admet	admet	PROPN
admet-159	292	12	&	&	CCONJ
admet-159	292	13	dmpk	dmpk	PROPN
admet-159	292	14	3(1	3(1	NUM
admet-159	292	15	)	)	PUNCT
admet-159	292	16	(	(	PUNCT
admet-159	292	17	2015	2015	NUM
admet-159	292	18	)	)	PUNCT
admet-159	292	19	15	15	NUM
admet-159	292	20	-	-	SYM
admet-159	292	21	33	33	NUM
admet-159	292	22	28	28	NUM
admet-159	292	23	that	that	PRON
admet-159	292	24	metabolizes	metabolize	VERB
admet-159	292	25	a	a	PRON
admet-159	292	26	-	-	PUNCT
admet-159	292	27	syn	syn	NOUN
admet-159	292	28	molecules	molecule	NOUN
admet-159	292	29	,	,	PUNCT
admet-159	292	30	which	which	PRON
admet-159	292	31	could	could	AUX
admet-159	292	32	alter	alter	VERB
admet-159	292	33	intracellular	intracellular	ADJ
admet-159	292	34	a	a	PRON
admet-159	292	35	-	-	PUNCT
admet-159	292	36	syn	syn	NOUN
admet-159	292	37	levels	level	NOUN
admet-159	292	38	.	.	PUNCT
admet-159	293	1	furthermore	furthermore	ADV
admet-159	293	2	,	,	PUNCT
admet-159	293	3	the	the	DET
admet-159	293	4	contrasting	contrast	VERB
admet-159	293	5	results	result	NOUN
admet-159	293	6	between	between	ADP
admet-159	293	7	the	the	DET
admet-159	293	8	decrease	decrease	NOUN
admet-159	293	9	in	in	ADP
admet-159	293	10	a	a	DET
admet-159	293	11	-	-	PUNCT
admet-159	293	12	syn	syn	NOUN
admet-159	293	13	signal	signal	NOUN
admet-159	293	14	following	follow	VERB
admet-159	293	15	48	48	NUM
admet-159	293	16	h	h	NOUN
admet-159	293	17	of	of	ADP
admet-159	293	18	mn	mn	PROPN
admet-159	293	19	exposure	exposure	NOUN
admet-159	293	20	in	in	ADP
admet-159	293	21	z310	z310	PROPN
admet-159	293	22	cells	cell	NOUN
admet-159	293	23	and	and	CCONJ
admet-159	293	24	the	the	DET
admet-159	293	25	increase	increase	NOUN
admet-159	293	26	in	in	ADP
admet-159	293	27	a	a	DET
admet-159	293	28	-	-	PUNCT
admet-159	293	29	syn	syn	NOUN
admet-159	293	30	signal	signal	NOUN
admet-159	293	31	in	in	ADP
admet-159	293	32	primary	primary	ADJ
admet-159	293	33	choroidal	choroidal	ADJ
admet-159	293	34	epithelia	epithelium	NOUN
admet-159	293	35	following	follow	VERB
admet-159	293	36	mn	mn	PROPN
admet-159	293	37	exposure	exposure	NOUN
admet-159	293	38	suggests	suggest	VERB
admet-159	293	39	that	that	SCONJ
admet-159	293	40	the	the	DET
admet-159	293	41	ability	ability	NOUN
admet-159	293	42	to	to	PART
admet-159	293	43	degrade	degrade	VERB
admet-159	293	44	asyn	asyn	ADJ
admet-159	293	45	aggregates	aggregate	NOUN
admet-159	293	46	induced	induce	VERB
admet-159	293	47	by	by	ADP
admet-159	293	48	mn	mn	PROPN
admet-159	293	49	exposure	exposure	NOUN
admet-159	293	50	differs	differ	VERB
admet-159	293	51	between	between	ADP
admet-159	293	52	the	the	DET
admet-159	293	53	primary	primary	ADJ
admet-159	293	54	cells	cell	NOUN
admet-159	293	55	and	and	CCONJ
admet-159	293	56	the	the	DET
admet-159	293	57	established	establish	VERB
admet-159	293	58	cell	cell	NOUN
admet-159	293	59	line	line	NOUN
admet-159	293	60	.	.	PUNCT
admet-159	294	1	additionally	additionally	ADV
admet-159	294	2	,	,	PUNCT
admet-159	294	3	our	our	PRON
admet-159	294	4	in	in	X
admet-159	294	5	vitro	vitro	X
admet-159	294	6	studies	study	NOUN
admet-159	294	7	with	with	ADP
admet-159	294	8	primary	primary	ADJ
admet-159	294	9	choroidal	choroidal	NOUN
admet-159	294	10	cells	cell	NOUN
admet-159	294	11	showed	show	VERB
admet-159	294	12	a	a	DET
admet-159	294	13	mn	mn	NOUN
admet-159	294	14	-	-	PUNCT
admet-159	294	15	induced	induce	VERB
admet-159	294	16	increase	increase	NOUN
admet-159	294	17	of	of	ADP
admet-159	294	18	a	a	DET
admet-159	294	19	-	-	PUNCT
admet-159	294	20	syn	syn	NOUN
admet-159	294	21	uptake	uptake	NOUN
admet-159	294	22	in	in	ADP
admet-159	294	23	the	the	DET
admet-159	294	24	presence	presence	NOUN
admet-159	294	25	of	of	ADP
admet-159	294	26	externally	externally	ADV
admet-159	294	27	added	add	VERB
admet-159	294	28	a	a	DET
admet-159	294	29	-	-	PUNCT
admet-159	294	30	syn	syn	NOUN
admet-159	294	31	.	.	PUNCT
admet-159	295	1	thus	thus	ADV
admet-159	295	2	,	,	PUNCT
admet-159	295	3	it	it	PRON
admet-159	295	4	seems	seem	VERB
admet-159	295	5	likely	likely	ADJ
admet-159	295	6	that	that	SCONJ
admet-159	295	7	mn	mn	PROPN
admet-159	295	8	exposure	exposure	NOUN
admet-159	295	9	may	may	AUX
admet-159	295	10	act	act	VERB
admet-159	295	11	on	on	ADP
admet-159	295	12	some	some	DET
admet-159	295	13	yet	yet	ADV
admet-159	295	14	unknown	unknown	ADJ
admet-159	295	15	mechanisms	mechanism	NOUN
admet-159	295	16	that	that	PRON
admet-159	295	17	transport	transport	VERB
admet-159	295	18	a	a	PRON
admet-159	295	19	-	-	PUNCT
admet-159	295	20	syn	syn	NOUN
admet-159	295	21	into	into	ADP
admet-159	295	22	the	the	DET
admet-159	295	23	cells	cell	NOUN
admet-159	295	24	.	.	PUNCT
admet-159	296	1	our	our	PRON
admet-159	296	2	observation	observation	NOUN
admet-159	296	3	of	of	ADP
admet-159	296	4	bright	bright	ADJ
admet-159	296	5	green	green	ADJ
admet-159	296	6	dots	dot	NOUN
admet-159	296	7	in	in	ADP
admet-159	296	8	the	the	DET
admet-159	296	9	plexus	plexus	NOUN
admet-159	296	10	tissues	tissue	NOUN
admet-159	296	11	appears	appear	VERB
admet-159	296	12	to	to	PART
admet-159	296	13	suggest	suggest	VERB
admet-159	296	14	an	an	DET
admet-159	296	15	aggregation	aggregation	NOUN
admet-159	296	16	of	of	ADP
admet-159	296	17	a	a	DET
admet-159	296	18	-	-	PUNCT
admet-159	296	19	syn	syn	NOUN
admet-159	296	20	within	within	ADP
admet-159	296	21	the	the	DET
admet-159	296	22	plexus	plexus	NOUN
admet-159	296	23	cells	cell	NOUN
admet-159	296	24	after	after	ADP
admet-159	296	25	mn	mn	PROPN
admet-159	296	26	exposure	exposure	NOUN
admet-159	296	27	.	.	PUNCT
admet-159	297	1	this	this	DET
admet-159	297	2	observation	observation	NOUN
admet-159	297	3	is	be	AUX
admet-159	297	4	in	in	ADP
admet-159	297	5	a	a	DET
admet-159	297	6	good	good	ADJ
admet-159	297	7	agreement	agreement	NOUN
admet-159	297	8	with	with	ADP
admet-159	297	9	previous	previous	ADJ
admet-159	297	10	findings	finding	NOUN
admet-159	297	11	in	in	ADP
admet-159	297	12	the	the	DET
admet-159	297	13	literature	literature	NOUN
admet-159	297	14	that	that	PRON
admet-159	297	15	a	a	DET
admet-159	297	16	direct	direct	ADJ
admet-159	297	17	incubation	incubation	NOUN
admet-159	297	18	of	of	ADP
admet-159	297	19	a	a	DET
admet-159	297	20	-	-	PUNCT
admet-159	297	21	syn	syn	NOUN
admet-159	297	22	with	with	ADP
admet-159	297	23	mn	mn	PROPN
admet-159	297	24	and	and	CCONJ
admet-159	297	25	cu	cu	PROPN
admet-159	297	26	can	can	AUX
admet-159	297	27	result	result	VERB
admet-159	297	28	in	in	ADP
admet-159	297	29	a	a	DET
admet-159	297	30	-	-	PUNCT
admet-159	297	31	syn	syn	NOUN
admet-159	297	32	aggregation	aggregation	NOUN
admet-159	298	1	[	[	X
admet-159	298	2	38,39,55,56	38,39,55,56	NUM
admet-159	298	3	]	]	PUNCT
admet-159	298	4	.	.	PUNCT
admet-159	299	1	the	the	DET
admet-159	299	2	findings	finding	NOUN
admet-159	299	3	from	from	ADP
admet-159	299	4	the	the	DET
admet-159	299	5	thiot	thiot	NOUN
admet-159	299	6	assay	assay	NOUN
admet-159	299	7	provide	provide	VERB
admet-159	299	8	further	further	ADJ
admet-159	299	9	evidence	evidence	NOUN
admet-159	299	10	to	to	PART
admet-159	299	11	support	support	VERB
admet-159	299	12	the	the	DET
admet-159	299	13	hypothesis	hypothesis	NOUN
admet-159	299	14	that	that	PRON
admet-159	299	15	mn	mn	PROPN
admet-159	299	16	exposure	exposure	NOUN
admet-159	299	17	induces	induce	VERB
admet-159	299	18	a	a	DET
admet-159	299	19	-	-	PUNCT
admet-159	299	20	syn	syn	NOUN
admet-159	299	21	aggregation	aggregation	NOUN
admet-159	299	22	in	in	ADP
admet-159	299	23	the	the	DET
admet-159	299	24	bcsfb	bcsfb	NOUN
admet-159	299	25	.	.	PUNCT
admet-159	300	1	remarkably	remarkably	ADV
admet-159	300	2	,	,	PUNCT
admet-159	300	3	however	however	ADV
admet-159	300	4	,	,	PUNCT
admet-159	300	5	the	the	DET
admet-159	300	6	aggregation	aggregation	NOUN
admet-159	300	7	rate	rate	NOUN
admet-159	300	8	of	of	ADP
admet-159	300	9	recombinant	recombinant	ADJ
admet-159	300	10	a	a	PRON
admet-159	300	11	-	-	PUNCT
admet-159	300	12	syn	syn	NOUN
admet-159	300	13	in	in	ADP
admet-159	300	14	the	the	DET
admet-159	300	15	thiot	thiot	NOUN
admet-159	300	16	assay	assay	NOUN
admet-159	300	17	did	do	AUX
admet-159	300	18	not	not	PART
admet-159	300	19	increase	increase	VERB
admet-159	300	20	,	,	PUNCT
admet-159	300	21	but	but	CCONJ
admet-159	300	22	rather	rather	ADV
admet-159	300	23	decreased	decrease	VERB
admet-159	300	24	,	,	PUNCT
admet-159	300	25	upon	upon	SCONJ
admet-159	300	26	concomitant	concomitant	ADJ
admet-159	300	27	incubation	incubation	NOUN
admet-159	300	28	with	with	ADP
admet-159	300	29	both	both	DET
admet-159	300	30	mn	mn	PROPN
admet-159	300	31	and	and	CCONJ
admet-159	300	32	cu	cu	PROPN
admet-159	300	33	,	,	PUNCT
admet-159	300	34	when	when	SCONJ
admet-159	300	35	the	the	DET
admet-159	300	36	data	datum	NOUN
admet-159	300	37	were	be	AUX
admet-159	300	38	compared	compare	VERB
admet-159	300	39	to	to	ADP
admet-159	300	40	that	that	PRON
admet-159	300	41	obtained	obtain	VERB
admet-159	300	42	for	for	ADP
admet-159	300	43	a	a	PRON
admet-159	300	44	-	-	PUNCT
admet-159	300	45	syn	syn	NOUN
admet-159	300	46	incubated	incubate	VERB
admet-159	300	47	with	with	ADP
admet-159	300	48	mn	mn	PROPN
admet-159	300	49	or	or	CCONJ
admet-159	300	50	cu	cu	PROPN
admet-159	300	51	,	,	PUNCT
admet-159	300	52	alone	alone	ADV
admet-159	300	53	.	.	PUNCT
admet-159	301	1	cu	cu	PROPN
admet-159	301	2	has	have	AUX
admet-159	301	3	been	be	AUX
admet-159	301	4	shown	show	VERB
admet-159	301	5	to	to	PART
admet-159	301	6	bind	bind	VERB
admet-159	301	7	to	to	ADP
admet-159	301	8	multiple	multiple	ADJ
admet-159	301	9	sites	site	NOUN
admet-159	301	10	on	on	ADP
admet-159	301	11	the	the	DET
admet-159	301	12	a	a	PROPN
admet-159	301	13	-	-	PUNCT
admet-159	301	14	syn	syn	NOUN
admet-159	301	15	protein	protein	NOUN
admet-159	301	16	[	[	X
admet-159	301	17	51,55,57,58	51,55,57,58	X
admet-159	301	18	]	]	PUNCT
admet-159	301	19	and	and	CCONJ
admet-159	301	20	undergo	undergo	VERB
admet-159	301	21	redox	redox	ADJ
admet-159	301	22	reactions	reaction	NOUN
admet-159	301	23	with	with	ADP
admet-159	301	24	a	a	PRON
admet-159	301	25	-	-	PUNCT
admet-159	301	26	syn	syn	NOUN
admet-159	301	27	directly	directly	ADV
admet-159	301	28	,	,	PUNCT
admet-159	301	29	by	by	ADP
admet-159	301	30	swapping	swap	VERB
admet-159	301	31	between	between	ADP
admet-159	301	32	cu(i	cu(i	NOUN
admet-159	301	33	)	)	PUNCT
admet-159	301	34	and	and	CCONJ
admet-159	301	35	cu(ii	cu(ii	PROPN
admet-159	301	36	)	)	PUNCT
admet-159	301	37	oxidation	oxidation	NOUN
admet-159	301	38	states	state	NOUN
admet-159	301	39	[	[	X
admet-159	301	40	58	58	NUM
admet-159	301	41	]	]	PUNCT
admet-159	301	42	.	.	PUNCT
admet-159	302	1	furthermore	furthermore	ADV
admet-159	302	2	,	,	PUNCT
admet-159	302	3	cu	cu	PROPN
admet-159	302	4	has	have	VERB
admet-159	302	5	different	different	ADJ
admet-159	302	6	preferred	preferred	ADJ
admet-159	302	7	binding	bind	VERB
admet-159	302	8	sites	site	NOUN
admet-159	302	9	to	to	ADP
admet-159	302	10	a	a	PRON
admet-159	302	11	-	-	PUNCT
admet-159	302	12	syn	syn	NOUN
admet-159	302	13	,	,	PUNCT
admet-159	302	14	depending	depend	VERB
admet-159	302	15	on	on	ADP
admet-159	302	16	its	its	PRON
admet-159	302	17	oxidation	oxidation	NOUN
admet-159	302	18	state	state	NOUN
admet-159	303	1	[	[	X
admet-159	303	2	53,55	53,55	NOUN
admet-159	303	3	]	]	PUNCT
admet-159	303	4	.	.	PUNCT
admet-159	304	1	these	these	DET
admet-159	304	2	facts	fact	NOUN
admet-159	304	3	suggest	suggest	VERB
admet-159	304	4	that	that	SCONJ
admet-159	304	5	cu	cu	PROPN
admet-159	304	6	can	can	AUX
admet-159	304	7	induce	induce	VERB
admet-159	304	8	a	a	DET
admet-159	304	9	-	-	PUNCT
admet-159	304	10	syn	syn	NOUN
admet-159	304	11	dysfunction	dysfunction	NOUN
admet-159	304	12	in	in	ADP
admet-159	304	13	a	a	DET
admet-159	304	14	variety	variety	NOUN
admet-159	304	15	of	of	ADP
admet-159	304	16	ways	way	NOUN
admet-159	304	17	.	.	PUNCT
admet-159	305	1	similar	similar	ADJ
admet-159	305	2	research	research	NOUN
admet-159	305	3	on	on	ADP
admet-159	305	4	mn	mn	PROPN
admet-159	305	5	/	/	SYM
admet-159	305	6	a	a	PROPN
admet-159	305	7	-	-	PUNCT
admet-159	305	8	syn	syn	NOUN
admet-159	305	9	interactions	interaction	NOUN
admet-159	305	10	is	be	AUX
admet-159	305	11	practically	practically	ADV
admet-159	305	12	non	non	ADJ
admet-159	305	13	-	-	ADJ
admet-159	305	14	existent	existent	ADJ
admet-159	305	15	.	.	PUNCT
admet-159	306	1	it	it	PRON
admet-159	306	2	is	be	AUX
admet-159	306	3	possible	possible	ADJ
admet-159	306	4	that	that	SCONJ
admet-159	306	5	mn	mn	PROPN
admet-159	306	6	may	may	AUX
admet-159	306	7	also	also	ADV
admet-159	306	8	have	have	VERB
admet-159	306	9	multiple	multiple	ADJ
admet-159	306	10	binding	bind	VERB
admet-159	306	11	sites	site	NOUN
admet-159	306	12	in	in	ADP
admet-159	306	13	a	a	DET
admet-159	306	14	-	-	PUNCT
admet-159	306	15	syn	syn	NOUN
admet-159	306	16	molecules	molecule	NOUN
admet-159	306	17	,	,	PUNCT
admet-159	306	18	similar	similar	ADJ
admet-159	306	19	to	to	ADP
admet-159	306	20	cu	cu	PROPN
admet-159	306	21	and	and	CCONJ
admet-159	306	22	other	other	ADJ
admet-159	306	23	metals	metal	NOUN
admet-159	306	24	[	[	X
admet-159	306	25	51	51	NUM
admet-159	306	26	]	]	PUNCT
admet-159	306	27	.	.	PUNCT
admet-159	307	1	in	in	ADP
admet-159	307	2	addition	addition	NOUN
admet-159	307	3	,	,	PUNCT
admet-159	307	4	mn	mn	PROPN
admet-159	307	5	might	might	AUX
admet-159	307	6	undergo	undergo	VERB
admet-159	307	7	direct	direct	ADJ
admet-159	307	8	redox	redox	ADJ
admet-159	307	9	reactions	reaction	NOUN
admet-159	307	10	with	with	ADP
admet-159	307	11	a	a	DET
admet-159	307	12	-	-	PUNCT
admet-159	307	13	syn	syn	NOUN
admet-159	307	14	,	,	PUNCT
admet-159	307	15	similar	similar	ADJ
admet-159	307	16	to	to	ADP
admet-159	307	17	cu	cu	PROPN
admet-159	307	18	.	.	PUNCT
admet-159	308	1	these	these	DET
admet-159	308	2	potential	potential	ADJ
admet-159	308	3	interactions	interaction	NOUN
admet-159	308	4	between	between	ADP
admet-159	308	5	metals	metal	NOUN
admet-159	308	6	themselves	themselves	PRON
admet-159	308	7	and	and	CCONJ
admet-159	308	8	among	among	ADP
admet-159	308	9	the	the	DET
admet-159	308	10	metals	metal	NOUN
admet-159	308	11	and	and	CCONJ
admet-159	308	12	the	the	DET
admet-159	308	13	protein	protein	NOUN
admet-159	308	14	may	may	AUX
admet-159	308	15	explain	explain	VERB
admet-159	308	16	our	our	PRON
admet-159	308	17	in	in	ADP
admet-159	308	18	vitro	vitro	X
admet-159	308	19	a	a	DET
admet-159	308	20	-	-	PUNCT
admet-159	308	21	syn	syn	NOUN
admet-159	308	22	aggregation	aggregation	NOUN
admet-159	308	23	data	datum	NOUN
admet-159	308	24	.	.	PUNCT
admet-159	309	1	clearly	clearly	ADV
admet-159	309	2	more	more	ADJ
admet-159	309	3	research	research	NOUN
admet-159	309	4	is	be	AUX
admet-159	309	5	necessary	necessary	ADJ
admet-159	309	6	to	to	PART
admet-159	309	7	depict	depict	VERB
admet-159	309	8	the	the	DET
admet-159	309	9	underlying	underlie	VERB
admet-159	309	10	mechanisms	mechanism	NOUN
admet-159	309	11	.	.	PUNCT
admet-159	310	1	the	the	DET
admet-159	310	2	results	result	NOUN
admet-159	310	3	from	from	ADP
admet-159	310	4	our	our	PRON
admet-159	310	5	ihc	ihc	NOUN
admet-159	310	6	and	and	CCONJ
admet-159	310	7	elisa	elisa	VERB
admet-159	310	8	quantifications	quantification	NOUN
admet-159	310	9	of	of	ADP
admet-159	310	10	a	a	DET
admet-159	310	11	-	-	PUNCT
admet-159	310	12	syn	syn	NOUN
admet-159	310	13	in	in	ADP
admet-159	310	14	rat	rat	NOUN
admet-159	310	15	primary	primary	ADJ
admet-159	310	16	choroidal	choroidal	ADJ
admet-159	310	17	epithelia	epithelia	PROPN
admet-159	310	18	following	follow	VERB
admet-159	310	19	mn	mn	PROPN
admet-159	310	20	exposure	exposure	NOUN
admet-159	310	21	showed	show	VERB
admet-159	310	22	conflicting	conflicting	ADJ
admet-159	310	23	results	result	NOUN
admet-159	310	24	.	.	PUNCT
admet-159	311	1	while	while	SCONJ
admet-159	311	2	the	the	DET
admet-159	311	3	results	result	NOUN
admet-159	311	4	from	from	ADP
admet-159	311	5	the	the	DET
admet-159	311	6	ihc	ihc	PROPN
admet-159	311	7	quantitation	quantitation	NOUN
admet-159	311	8	demonstrated	demonstrate	VERB
admet-159	311	9	a	a	DET
admet-159	311	10	mninduced	mninduced	ADJ
admet-159	311	11	a	a	DET
admet-159	311	12	-	-	PUNCT
admet-159	311	13	syn	syn	NOUN
admet-159	311	14	accumulation	accumulation	NOUN
admet-159	311	15	and	and	CCONJ
admet-159	311	16	significantly	significantly	ADV
admet-159	311	17	increased	increase	VERB
admet-159	311	18	uptake	uptake	NOUN
admet-159	311	19	of	of	ADP
admet-159	311	20	a	a	DET
admet-159	311	21	-	-	PUNCT
admet-159	311	22	syn	syn	NOUN
admet-159	311	23	from	from	ADP
admet-159	311	24	the	the	DET
admet-159	311	25	external	external	ADJ
admet-159	311	26	environment	environment	NOUN
admet-159	311	27	(	(	PUNCT
admet-159	311	28	compared	compare	VERB
admet-159	311	29	to	to	ADP
admet-159	311	30	controls	control	NOUN
admet-159	311	31	)	)	PUNCT
admet-159	311	32	,	,	PUNCT
admet-159	311	33	the	the	DET
admet-159	311	34	results	result	NOUN
admet-159	311	35	from	from	ADP
admet-159	311	36	the	the	DET
admet-159	311	37	elisa	elisa	NOUN
admet-159	311	38	quantification	quantification	NOUN
admet-159	311	39	showed	show	VERB
admet-159	311	40	a	a	DET
admet-159	311	41	decrease	decrease	NOUN
admet-159	311	42	in	in	ADP
admet-159	311	43	a	a	DET
admet-159	311	44	-	-	PUNCT
admet-159	311	45	syn	syn	NOUN
admet-159	311	46	concentrations	concentration	NOUN
admet-159	311	47	following	follow	VERB
admet-159	311	48	mn	mn	PROPN
admet-159	311	49	exposure	exposure	NOUN
admet-159	311	50	.	.	PUNCT
admet-159	312	1	the	the	DET
admet-159	312	2	elisa	elisa	PROPN
admet-159	312	3	kit	kit	PROPN
admet-159	312	4	,	,	PUNCT
admet-159	312	5	however	however	ADV
admet-159	312	6	,	,	PUNCT
admet-159	312	7	is	be	AUX
admet-159	312	8	designed	design	VERB
admet-159	312	9	to	to	PART
admet-159	312	10	detect	detect	VERB
admet-159	312	11	a	a	DET
admet-159	312	12	-	-	PUNCT
admet-159	312	13	syn	syn	NOUN
admet-159	312	14	monomer	monomer	NOUN
admet-159	312	15	only	only	ADV
admet-159	312	16	.	.	PUNCT
admet-159	313	1	the	the	DET
admet-159	313	2	confocal	confocal	ADJ
admet-159	313	3	data	datum	NOUN
admet-159	313	4	from	from	ADP
admet-159	313	5	the	the	DET
admet-159	313	6	uptake	uptake	ADJ
admet-159	313	7	studies	study	NOUN
admet-159	313	8	revealed	reveal	VERB
admet-159	313	9	a	a	DET
admet-159	313	10	-	-	PUNCT
admet-159	313	11	syn	syn	NOUN
admet-159	313	12	accumulation	accumulation	NOUN
admet-159	313	13	in	in	ADP
admet-159	313	14	mn	mn	PROPN
admet-159	313	15	-	-	PUNCT
admet-159	313	16	treated	treat	VERB
admet-159	313	17	cells	cell	NOUN
admet-159	313	18	,	,	PUNCT
admet-159	313	19	and	and	CCONJ
admet-159	313	20	the	the	DET
admet-159	313	21	thiot	thiot	NOUN
admet-159	313	22	assay	assay	NOUN
admet-159	313	23	clearly	clearly	ADV
admet-159	313	24	showed	show	VERB
admet-159	313	25	a	a	DET
admet-159	313	26	-	-	PUNCT
admet-159	313	27	syn	syn	NOUN
admet-159	313	28	aggregation	aggregation	NOUN
admet-159	313	29	occurring	occur	VERB
admet-159	313	30	in	in	ADP
admet-159	313	31	the	the	DET
admet-159	313	32	presence	presence	NOUN
admet-159	313	33	of	of	ADP
admet-159	313	34	mn	mn	PROPN
admet-159	313	35	.	.	PUNCT
admet-159	314	1	therefore	therefore	ADV
admet-159	314	2	,	,	PUNCT
admet-159	314	3	we	we	PRON
admet-159	314	4	propose	propose	VERB
admet-159	314	5	that	that	SCONJ
admet-159	314	6	the	the	DET
admet-159	314	7	decrease	decrease	NOUN
admet-159	314	8	in	in	ADP
admet-159	314	9	a	a	DET
admet-159	314	10	-	-	PUNCT
admet-159	314	11	syn	syn	NOUN
admet-159	314	12	content	content	NOUN
admet-159	314	13	after	after	SCONJ
admet-159	314	14	mn	mn	PROPN
admet-159	314	15	treatment	treatment	NOUN
admet-159	314	16	determined	determine	VERB
admet-159	314	17	by	by	ADP
admet-159	314	18	elisa	elisa	PROPN
admet-159	314	19	may	may	AUX
admet-159	314	20	be	be	AUX
admet-159	314	21	the	the	DET
admet-159	314	22	result	result	NOUN
admet-159	314	23	of	of	ADP
admet-159	314	24	a	a	DET
admet-159	314	25	loss	loss	NOUN
admet-159	314	26	of	of	ADP
admet-159	314	27	a	a	DET
admet-159	314	28	-	-	PUNCT
admet-159	314	29	syn	syn	NOUN
admet-159	314	30	monomer	monomer	NOUN
admet-159	314	31	caused	cause	VERB
admet-159	314	32	by	by	ADP
admet-159	314	33	mn	mn	PROPN
admet-159	314	34	-	-	PUNCT
admet-159	314	35	induced	induce	VERB
admet-159	314	36	aggregation	aggregation	NOUN
admet-159	314	37	of	of	ADP
admet-159	314	38	the	the	DET
admet-159	314	39	protein	protein	NOUN
admet-159	314	40	.	.	PUNCT
admet-159	315	1	the	the	DET
admet-159	315	2	two	two	NUM
admet-159	315	3	-	-	PUNCT
admet-159	315	4	chamber	chamber	NOUN
admet-159	315	5	transwell	transwell	NOUN
admet-159	315	6	model	model	NOUN
admet-159	315	7	cultured	culture	VERB
admet-159	315	8	with	with	ADP
admet-159	315	9	primary	primary	ADJ
admet-159	315	10	choroidal	choroidal	ADJ
admet-159	315	11	epithelial	epithelial	ADJ
admet-159	315	12	cells	cell	NOUN
admet-159	315	13	is	be	AUX
admet-159	315	14	a	a	DET
admet-159	315	15	useful	useful	ADJ
admet-159	315	16	model	model	NOUN
admet-159	315	17	to	to	PART
admet-159	315	18	study	study	VERB
admet-159	315	19	the	the	DET
admet-159	315	20	directional	directional	ADJ
admet-159	315	21	transport	transport	NOUN
admet-159	315	22	of	of	ADP
admet-159	315	23	substances	substance	NOUN
admet-159	315	24	across	across	ADP
admet-159	315	25	the	the	DET
admet-159	315	26	bcsfb	bcsfb	NOUN
admet-159	315	27	,	,	PUNCT
admet-159	315	28	because	because	SCONJ
admet-159	315	29	the	the	DET
admet-159	315	30	monolayer	monolayer	NOUN
admet-159	315	31	of	of	ADP
admet-159	315	32	epithelial	epithelial	ADJ
admet-159	315	33	cells	cell	NOUN
admet-159	315	34	tends	tend	VERB
admet-159	315	35	to	to	PART
admet-159	315	36	form	form	VERB
admet-159	315	37	the	the	DET
admet-159	315	38	polarized	polarize	VERB
admet-159	315	39	cellular	cellular	ADJ
admet-159	315	40	architecture	architecture	NOUN
admet-159	315	41	with	with	ADP
admet-159	315	42	microvilli	microvilli	NOUN
admet-159	315	43	protruding	protrude	VERB
admet-159	315	44	to	to	ADP
admet-159	315	45	the	the	DET
admet-159	315	46	inner	inner	ADJ
admet-159	315	47	chamber	chamber	NOUN
admet-159	315	48	culture	culture	NOUN
admet-159	315	49	medium	medium	NOUN
admet-159	316	1	[	[	X
admet-159	316	2	42	42	NUM
admet-159	316	3	]	]	PUNCT
admet-159	316	4	.	.	PUNCT
admet-159	317	1	the	the	DET
admet-159	317	2	results	result	NOUN
admet-159	317	3	from	from	ADP
admet-159	317	4	our	our	PRON
admet-159	317	5	transwell	transwell	NOUN
admet-159	317	6	study	study	NOUN
admet-159	317	7	showed	show	VERB
admet-159	317	8	that	that	SCONJ
admet-159	317	9	the	the	DET
admet-159	317	10	bcsfb	bcsfb	NOUN
admet-159	317	11	monolayer	monolayer	NOUN
admet-159	317	12	was	be	AUX
admet-159	317	13	capable	capable	ADJ
admet-159	317	14	of	of	ADP
admet-159	317	15	transporting	transport	VERB
admet-159	317	16	a	a	PRON
admet-159	317	17	-	-	PUNCT
admet-159	317	18	syn	syn	NOUN
admet-159	317	19	in	in	ADP
admet-159	317	20	either	either	DET
admet-159	317	21	direction	direction	NOUN
admet-159	317	22	without	without	ADP
admet-159	317	23	specific	specific	ADJ
admet-159	317	24	preference	preference	NOUN
admet-159	317	25	toward	toward	ADP
admet-159	317	26	either	either	DET
admet-159	317	27	chamber	chamber	NOUN
admet-159	317	28	and	and	CCONJ
admet-159	317	29	that	that	SCONJ
admet-159	317	30	a	a	X
admet-159	317	31	-	-	PUNCT
admet-159	317	32	syn	syn	NOUN
admet-159	317	33	transport	transport	NOUN
admet-159	317	34	by	by	ADP
admet-159	317	35	the	the	DET
admet-159	317	36	bcsfb	bcsfb	NOUN
admet-159	317	37	was	be	AUX
admet-159	317	38	unaffected	unaffected	ADJ
admet-159	317	39	by	by	ADP
admet-159	317	40	mn	mn	PROPN
admet-159	317	41	exposure	exposure	NOUN
admet-159	317	42	.	.	PUNCT
admet-159	318	1	it	it	PRON
admet-159	318	2	is	be	AUX
admet-159	318	3	possible	possible	ADJ
admet-159	318	4	that	that	SCONJ
admet-159	318	5	a	a	DET
admet-159	318	6	severe	severe	ADJ
admet-159	318	7	leakage	leakage	NOUN
admet-159	318	8	of	of	ADP
admet-159	318	9	the	the	DET
admet-159	318	10	monolayer	monolayer	NOUN
admet-159	318	11	,	,	PUNCT
admet-159	318	12	either	either	CCONJ
admet-159	318	13	due	due	ADP
admet-159	318	14	to	to	ADP
admet-159	318	15	mn	mn	PROPN
admet-159	318	16	insults	insult	NOUN
admet-159	318	17	or	or	CCONJ
admet-159	318	18	a	a	DET
admet-159	318	19	-	-	PUNCT
admet-159	318	20	syn	syn	NOUN
admet-159	318	21	toxicity	toxicity	NOUN
admet-159	318	22	,	,	PUNCT
admet-159	318	23	may	may	AUX
admet-159	318	24	render	render	VERB
admet-159	318	25	the	the	DET
admet-159	318	26	barrier	barrier	NOUN
admet-159	318	27	inefficient	inefficient	ADJ
admet-159	318	28	to	to	ADP
admet-159	318	29	passing	pass	VERB
admet-159	318	30	molecules	molecule	NOUN
admet-159	318	31	.	.	PUNCT
admet-159	319	1	however	however	ADV
admet-159	319	2	,	,	PUNCT
admet-159	319	3	in	in	ADP
admet-159	319	4	both	both	CCONJ
admet-159	319	5	influx	influx	VERB
admet-159	319	6	and	and	CCONJ
admet-159	319	7	efflux	efflux	VERB
admet-159	319	8	studies	study	NOUN
admet-159	319	9	,	,	PUNCT
admet-159	319	10	the	the	DET
admet-159	319	11	levels	level	NOUN
admet-159	319	12	of	of	ADP
admet-159	319	13	a	a	DET
admet-159	319	14	-	-	PUNCT
admet-159	319	15	syn	syn	NOUN
admet-159	319	16	in	in	ADP
admet-159	319	17	the	the	DET
admet-159	319	18	donor	donor	NOUN
admet-159	319	19	chambers	chamber	NOUN
admet-159	319	20	were	be	AUX
admet-159	319	21	significantly	significantly	ADV
admet-159	319	22	lower	low	ADJ
admet-159	319	23	than	than	ADP
admet-159	319	24	those	those	PRON
admet-159	319	25	in	in	ADP
admet-159	319	26	the	the	DET
admet-159	319	27	receiver	receiver	ADJ
admet-159	319	28	chambers	chamber	NOUN
admet-159	319	29	at	at	ADP
admet-159	319	30	nearly	nearly	ADV
admet-159	319	31	all	all	PRON
admet-159	319	32	time	time	NOUN
admet-159	319	33	points	point	NOUN
admet-159	319	34	;	;	PUNCT
admet-159	319	35	these	these	DET
admet-159	319	36	data	datum	NOUN
admet-159	319	37	appear	appear	VERB
admet-159	319	38	to	to	PART
admet-159	319	39	suggest	suggest	VERB
admet-159	319	40	an	an	DET
admet-159	319	41	active	active	ADJ
admet-159	319	42	transport	transport	NOUN
admet-159	319	43	,	,	PUNCT
admet-159	319	44	rather	rather	ADV
admet-159	319	45	than	than	ADP
admet-159	319	46	a	a	DET
admet-159	319	47	passive	passive	ADJ
admet-159	319	48	diffusion	diffusion	NOUN
admet-159	319	49	,	,	PUNCT
admet-159	319	50	of	of	ADP
admet-159	319	51	a	a	DET
admet-159	319	52	-	-	PUNCT
admet-159	319	53	syn	syn	NOUN
admet-159	319	54	from	from	ADP
admet-159	319	55	the	the	DET
admet-159	319	56	donor	donor	NOUN
admet-159	319	57	to	to	ADP
admet-159	319	58	receiver	receiver	ADJ
admet-159	319	59	chamber	chamber	NOUN
admet-159	319	60	.	.	PUNCT
admet-159	320	1	this	this	DET
admet-159	320	2	hypothesis	hypothesis	NOUN
admet-159	320	3	deserves	deserve	VERB
admet-159	320	4	further	further	ADJ
admet-159	320	5	investigation	investigation	NOUN
admet-159	320	6	such	such	ADJ
admet-159	320	7	as	as	ADP
admet-159	320	8	by	by	ADP
admet-159	320	9	using	use	VERB
admet-159	320	10	atp	atp	PROPN
admet-159	320	11	production	production	NOUN
admet-159	320	12	inhibitors	inhibitor	NOUN
admet-159	320	13	.	.	PUNCT
admet-159	321	1	admet	admet	PROPN
admet-159	321	2	&	&	CCONJ
admet-159	321	3	dmpk	dmpk	PROPN
admet-159	321	4	3(1	3(1	NUM
admet-159	321	5	)	)	PUNCT
admet-159	321	6	(	(	PUNCT
admet-159	321	7	2015	2015	NUM
admet-159	321	8	)	)	PUNCT
admet-159	321	9	15	15	NUM
admet-159	321	10	-	-	SYM
admet-159	321	11	33	33	NUM
admet-159	321	12	effects	effect	NOUN
admet-159	321	13	of	of	ADP
admet-159	321	14	manganese	manganese	ADJ
admet-159	321	15	exposure	exposure	NOUN
admet-159	321	16	on	on	ADP
admet-159	321	17	expression	expression	NOUN
admet-159	321	18	and	and	CCONJ
admet-159	321	19	transport	transport	NOUN
admet-159	321	20	of	of	ADP
admet-159	321	21	-synuclein	-synuclein	PROPN
admet-159	321	22	doi	doi	NOUN
admet-159	321	23	:	:	PUNCT
admet-159	321	24	10.5599	10.5599	NUM
admet-159	321	25	/	/	SYM
admet-159	321	26	admet.3.1.159	admet.3.1.159	NUM
admet-159	321	27	29	29	NUM
admet-159	321	28	quantification	quantification	NOUN
admet-159	321	29	of	of	ADP
admet-159	321	30	a	a	PRON
admet-159	321	31	-	-	PUNCT
admet-159	321	32	syn	syn	NOUN
admet-159	321	33	levels	level	NOUN
admet-159	321	34	in	in	ADP
admet-159	321	35	chamber	chamber	NOUN
admet-159	321	36	cells	cell	NOUN
admet-159	321	37	did	do	AUX
admet-159	321	38	not	not	PART
admet-159	321	39	reveal	reveal	VERB
admet-159	321	40	any	any	DET
admet-159	321	41	significant	significant	ADJ
admet-159	321	42	changes	change	NOUN
admet-159	321	43	after	after	ADP
admet-159	321	44	mn	mn	PROPN
admet-159	321	45	exposure	exposure	NOUN
admet-159	321	46	.	.	PUNCT
admet-159	322	1	this	this	DET
admet-159	322	2	observation	observation	NOUN
admet-159	322	3	was	be	AUX
admet-159	322	4	in	in	ADP
admet-159	322	5	contrast	contrast	NOUN
admet-159	322	6	to	to	ADP
admet-159	322	7	the	the	DET
admet-159	322	8	results	result	NOUN
admet-159	322	9	with	with	ADP
admet-159	322	10	the	the	DET
admet-159	322	11	same	same	ADJ
admet-159	322	12	primary	primary	ADJ
admet-159	322	13	plexus	plexus	NOUN
admet-159	322	14	cells	cell	NOUN
admet-159	322	15	in	in	ADP
admet-159	322	16	the	the	DET
admet-159	322	17	uptake	uptake	ADJ
admet-159	322	18	study	study	NOUN
admet-159	322	19	.	.	PUNCT
admet-159	323	1	in	in	ADP
admet-159	323	2	the	the	DET
admet-159	323	3	uptake	uptake	ADJ
admet-159	323	4	study	study	NOUN
admet-159	323	5	,	,	PUNCT
admet-159	323	6	there	there	PRON
admet-159	323	7	was	be	VERB
admet-159	323	8	an	an	DET
admet-159	323	9	increased	increase	VERB
admet-159	323	10	accumulation	accumulation	NOUN
admet-159	323	11	of	of	ADP
admet-159	323	12	a	a	DET
admet-159	323	13	-	-	PUNCT
admet-159	323	14	syn	syn	NOUN
admet-159	323	15	when	when	SCONJ
admet-159	323	16	the	the	DET
admet-159	323	17	cells	cell	NOUN
admet-159	323	18	were	be	AUX
admet-159	323	19	exposed	expose	VERB
admet-159	323	20	to	to	ADP
admet-159	323	21	mn	mn	PROPN
admet-159	323	22	.	.	PUNCT
admet-159	324	1	a	a	DET
admet-159	324	2	plausible	plausible	ADJ
admet-159	324	3	reason	reason	NOUN
admet-159	324	4	for	for	ADP
admet-159	324	5	this	this	DET
admet-159	324	6	discrepancy	discrepancy	NOUN
admet-159	324	7	is	be	AUX
admet-159	324	8	that	that	SCONJ
admet-159	324	9	the	the	DET
admet-159	324	10	primary	primary	ADJ
admet-159	324	11	choroidal	choroidal	ADJ
admet-159	324	12	cells	cell	NOUN
admet-159	324	13	in	in	ADP
admet-159	324	14	the	the	DET
admet-159	324	15	a	a	NOUN
admet-159	324	16	-	-	PUNCT
admet-159	324	17	syn	syn	NOUN
admet-159	324	18	uptake	uptake	ADJ
admet-159	324	19	experiment	experiment	NOUN
admet-159	324	20	did	do	AUX
admet-159	324	21	not	not	PART
admet-159	324	22	have	have	VERB
admet-159	324	23	a	a	DET
admet-159	324	24	compartment	compartment	NOUN
admet-159	324	25	on	on	ADP
admet-159	324	26	the	the	DET
admet-159	324	27	basolateral	basolateral	ADJ
admet-159	324	28	side	side	NOUN
admet-159	324	29	to	to	PART
admet-159	324	30	expel	expel	VERB
admet-159	324	31	the	the	DET
admet-159	324	32	excess	excess	ADJ
admet-159	324	33	a	a	PRON
admet-159	324	34	-	-	PUNCT
admet-159	324	35	syn	syn	NOUN
admet-159	324	36	taken	take	VERB
admet-159	324	37	up	up	ADP
admet-159	324	38	by	by	ADP
admet-159	324	39	the	the	DET
admet-159	324	40	cells	cell	NOUN
admet-159	324	41	.	.	PUNCT
admet-159	325	1	this	this	PRON
admet-159	325	2	would	would	AUX
admet-159	325	3	lead	lead	VERB
admet-159	325	4	to	to	ADP
admet-159	325	5	excessive	excessive	ADJ
admet-159	325	6	accumulation	accumulation	NOUN
admet-159	325	7	of	of	ADP
admet-159	325	8	a	a	DET
admet-159	325	9	-	-	PUNCT
admet-159	325	10	syn	syn	NOUN
admet-159	325	11	in	in	ADP
admet-159	325	12	the	the	DET
admet-159	325	13	cells	cell	NOUN
admet-159	325	14	.	.	PUNCT
admet-159	326	1	the	the	DET
admet-159	326	2	primary	primary	ADJ
admet-159	326	3	cells	cell	NOUN
admet-159	326	4	cultured	cultured	ADJ
admet-159	326	5	on	on	ADP
admet-159	326	6	the	the	DET
admet-159	326	7	membrane	membrane	NOUN
admet-159	326	8	of	of	ADP
admet-159	326	9	the	the	DET
admet-159	326	10	transwell	transwell	NOUN
admet-159	326	11	inserts	insert	NOUN
admet-159	326	12	,	,	PUNCT
admet-159	326	13	however	however	ADV
admet-159	326	14	,	,	PUNCT
admet-159	326	15	possess	possess	VERB
admet-159	326	16	compartments	compartment	NOUN
admet-159	326	17	on	on	ADP
admet-159	326	18	both	both	DET
admet-159	326	19	sides	side	NOUN
admet-159	326	20	of	of	ADP
admet-159	326	21	the	the	DET
admet-159	326	22	bcsfb	bcsfb	NOUN
admet-159	326	23	monolayer	monolayer	NOUN
admet-159	326	24	in	in	ADP
admet-159	326	25	the	the	DET
admet-159	326	26	transwell	transwell	NOUN
admet-159	326	27	system	system	NOUN
admet-159	326	28	.	.	PUNCT
admet-159	327	1	therefore	therefore	ADV
admet-159	327	2	,	,	PUNCT
admet-159	327	3	the	the	DET
admet-159	327	4	cells	cell	NOUN
admet-159	327	5	could	could	AUX
admet-159	327	6	effectively	effectively	ADV
admet-159	327	7	expel	expel	VERB
admet-159	327	8	the	the	DET
admet-159	327	9	excess	excess	ADJ
admet-159	327	10	a	a	NOUN
admet-159	327	11	-	-	PUNCT
admet-159	327	12	syn	syn	NOUN
admet-159	327	13	in	in	ADP
admet-159	327	14	either	either	DET
admet-159	327	15	direction	direction	NOUN
admet-159	327	16	to	to	ADP
admet-159	327	17	the	the	DET
admet-159	327	18	extracellular	extracellular	ADJ
admet-159	327	19	culture	culture	NOUN
admet-159	327	20	medium	medium	NOUN
admet-159	327	21	.	.	PUNCT
admet-159	328	1	at	at	ADP
admet-159	328	2	present	present	ADJ
admet-159	328	3	,	,	PUNCT
admet-159	328	4	the	the	DET
admet-159	328	5	mechanism	mechanism	NOUN
admet-159	328	6	by	by	ADP
admet-159	328	7	which	which	PRON
admet-159	328	8	a	a	X
admet-159	328	9	-	-	PUNCT
admet-159	328	10	syn	syn	NOUN
admet-159	328	11	is	be	AUX
admet-159	328	12	expelled	expel	VERB
admet-159	328	13	out	out	ADP
admet-159	328	14	of	of	ADP
admet-159	328	15	these	these	DET
admet-159	328	16	bcsfb	bcsfb	ADJ
admet-159	328	17	cells	cell	NOUN
admet-159	328	18	is	be	AUX
admet-159	328	19	unknown	unknown	ADJ
admet-159	328	20	.	.	PUNCT
admet-159	329	1	thus	thus	ADV
admet-159	329	2	,	,	PUNCT
admet-159	329	3	it	it	PRON
admet-159	329	4	has	have	AUX
admet-159	329	5	become	become	VERB
admet-159	329	6	absolutely	absolutely	ADV
admet-159	329	7	necessary	necessary	ADJ
admet-159	329	8	to	to	PART
admet-159	329	9	investigate	investigate	VERB
admet-159	329	10	how	how	SCONJ
admet-159	329	11	a	a	X
admet-159	329	12	-	-	PUNCT
admet-159	329	13	syn	syn	NOUN
admet-159	329	14	is	be	AUX
admet-159	329	15	transported	transport	VERB
admet-159	329	16	by	by	ADP
admet-159	329	17	the	the	DET
admet-159	329	18	bcsfb	bcsfb	NOUN
admet-159	329	19	and	and	CCONJ
admet-159	329	20	what	what	PRON
admet-159	329	21	are	be	AUX
admet-159	329	22	the	the	DET
admet-159	329	23	clinical	clinical	ADJ
admet-159	329	24	implications	implication	NOUN
admet-159	329	25	if	if	SCONJ
admet-159	329	26	these	these	DET
admet-159	329	27	naturally	naturally	ADV
admet-159	329	28	present	present	ADJ
admet-159	329	29	transport	transport	NOUN
admet-159	329	30	machineries	machinery	NOUN
admet-159	329	31	are	be	AUX
admet-159	329	32	altered	alter	VERB
admet-159	329	33	due	due	ADP
admet-159	329	34	to	to	ADP
admet-159	329	35	genetic	genetic	ADJ
admet-159	329	36	defects	defect	NOUN
admet-159	329	37	,	,	PUNCT
admet-159	329	38	environmental	environmental	ADJ
admet-159	329	39	insults	insult	NOUN
admet-159	329	40	,	,	PUNCT
admet-159	329	41	or	or	CCONJ
admet-159	329	42	both	both	PRON
admet-159	329	43	.	.	PUNCT
admet-159	330	1	in	in	ADP
admet-159	330	2	summary	summary	NOUN
admet-159	330	3	,	,	PUNCT
admet-159	330	4	our	our	PRON
admet-159	330	5	findings	finding	NOUN
admet-159	330	6	reveal	reveal	VERB
admet-159	330	7	that	that	SCONJ
admet-159	330	8	the	the	DET
admet-159	330	9	bcsfb	bcsfb	NOUN
admet-159	330	10	expresses	express	VERB
admet-159	330	11	a	a	DET
admet-159	330	12	-	-	PUNCT
admet-159	330	13	syn	syn	NOUN
admet-159	330	14	endogenously	endogenously	ADV
admet-159	330	15	and	and	CCONJ
admet-159	330	16	is	be	AUX
admet-159	330	17	capable	capable	ADJ
admet-159	330	18	of	of	ADP
admet-159	330	19	transporting	transport	VERB
admet-159	330	20	a	a	DET
admet-159	330	21	-	-	PUNCT
admet-159	330	22	syn	syn	NOUN
admet-159	330	23	between	between	ADP
admet-159	330	24	the	the	DET
admet-159	330	25	blood	blood	NOUN
admet-159	330	26	and	and	CCONJ
admet-159	330	27	csf	csf	PROPN
admet-159	330	28	.	.	PROPN
admet-159	330	29	exposure	exposure	NOUN
admet-159	330	30	to	to	ADP
admet-159	330	31	mn	mn	PROPN
admet-159	330	32	increases	increase	VERB
admet-159	330	33	the	the	DET
admet-159	330	34	uptake	uptake	NOUN
admet-159	330	35	of	of	ADP
admet-159	330	36	a	a	DET
admet-159	330	37	-	-	PUNCT
admet-159	330	38	syn	syn	NOUN
admet-159	330	39	in	in	ADP
admet-159	330	40	choroid	choroid	ADJ
admet-159	330	41	epithelial	epithelial	ADJ
admet-159	330	42	cells	cell	NOUN
admet-159	330	43	,	,	PUNCT
admet-159	330	44	but	but	CCONJ
admet-159	330	45	does	do	AUX
admet-159	330	46	not	not	PART
admet-159	330	47	have	have	VERB
admet-159	330	48	any	any	DET
admet-159	330	49	apparent	apparent	ADJ
admet-159	330	50	effect	effect	NOUN
admet-159	330	51	on	on	ADP
admet-159	330	52	a	a	DET
admet-159	330	53	-	-	PUNCT
admet-159	330	54	syn	syn	NOUN
admet-159	330	55	transport	transport	NOUN
admet-159	330	56	across	across	ADP
admet-159	330	57	the	the	DET
admet-159	330	58	bcsfb	bcsfb	NOUN
admet-159	330	59	.	.	PUNCT
admet-159	331	1	the	the	DET
admet-159	331	2	clinical	clinical	ADJ
admet-159	331	3	relevance	relevance	NOUN
admet-159	331	4	of	of	ADP
admet-159	331	5	these	these	DET
admet-159	331	6	observations	observation	NOUN
admet-159	331	7	to	to	ADP
admet-159	331	8	mn	mn	PROPN
admet-159	331	9	-	-	PUNCT
admet-159	331	10	induced	induce	VERB
admet-159	331	11	parkinsonian	parkinsonian	ADJ
admet-159	331	12	disorder	disorder	NOUN
admet-159	331	13	remains	remain	VERB
admet-159	331	14	unclear	unclear	ADJ
admet-159	331	15	.	.	PUNCT
admet-159	332	1	the	the	DET
admet-159	332	2	current	current	ADJ
admet-159	332	3	study	study	NOUN
admet-159	332	4	represents	represent	VERB
admet-159	332	5	the	the	DET
admet-159	332	6	initial	initial	ADJ
admet-159	332	7	steps	step	NOUN
admet-159	332	8	that	that	PRON
admet-159	332	9	have	have	AUX
admet-159	332	10	provided	provide	VERB
admet-159	332	11	the	the	DET
admet-159	332	12	foundation	foundation	NOUN
admet-159	332	13	for	for	ADP
admet-159	332	14	further	further	ADJ
admet-159	332	15	investigation	investigation	NOUN
admet-159	332	16	of	of	ADP
admet-159	332	17	a	a	DET
admet-159	332	18	-	-	PUNCT
admet-159	332	19	syn	syn	NOUN
admet-159	332	20	transport	transport	NOUN
admet-159	332	21	at	at	ADP
admet-159	332	22	the	the	DET
admet-159	332	23	bcsfb	bcsfb	NOUN
admet-159	332	24	in	in	ADP
admet-159	332	25	health	health	NOUN
admet-159	332	26	and	and	CCONJ
admet-159	332	27	disease	disease	NOUN
admet-159	332	28	conditions	condition	NOUN
admet-159	332	29	.	.	PUNCT
admet-159	333	1	competing	compete	VERB
admet-159	333	2	interests	interest	NOUN
admet-159	333	3	the	the	DET
admet-159	333	4	authors	author	NOUN
admet-159	333	5	declare	declare	VERB
admet-159	333	6	that	that	SCONJ
admet-159	333	7	there	there	PRON
admet-159	333	8	are	be	VERB
admet-159	333	9	no	no	DET
admet-159	333	10	financial	financial	ADJ
admet-159	333	11	or	or	CCONJ
admet-159	333	12	non	non	ADJ
admet-159	333	13	-	-	ADJ
admet-159	333	14	financial	financial	ADJ
admet-159	333	15	competing	compete	VERB
admet-159	333	16	interests	interest	NOUN
admet-159	333	17	.	.	PUNCT
admet-159	334	1	authors	author	NOUN
admet-159	334	2	’	’	PART
admet-159	334	3	contributions	contribution	NOUN
admet-159	334	4	cb	cb	PROPN
admet-159	334	5	and	and	CCONJ
admet-159	334	6	wz	wz	AUX
admet-159	334	7	designed	design	VERB
admet-159	334	8	experiments	experiment	NOUN
admet-159	334	9	;	;	PUNCT
admet-159	334	10	cb	cb	PROPN
admet-159	334	11	,	,	PUNCT
admet-159	334	12	sf	sf	PROPN
admet-159	334	13	,	,	PUNCT
admet-159	334	14	and	and	CCONJ
admet-159	334	15	dy	dy	NOUN
admet-159	334	16	participated	participate	VERB
admet-159	334	17	in	in	ADP
admet-159	334	18	the	the	DET
admet-159	334	19	acquisition	acquisition	NOUN
admet-159	334	20	of	of	ADP
admet-159	334	21	the	the	DET
admet-159	334	22	data	datum	NOUN
admet-159	334	23	.	.	PUNCT
admet-159	335	1	cb	cb	PROPN
admet-159	335	2	drafted	draft	VERB
admet-159	335	3	and	and	CCONJ
admet-159	335	4	wrote	write	VERB
admet-159	335	5	the	the	DET
admet-159	335	6	manuscript	manuscript	NOUN
admet-159	335	7	.	.	PUNCT
admet-159	336	1	wz	wz	PROPN
admet-159	336	2	and	and	CCONJ
admet-159	336	3	jr	jr	PROPN
admet-159	336	4	commented	comment	VERB
admet-159	336	5	and	and	CCONJ
admet-159	336	6	revised	revise	VERB
admet-159	336	7	the	the	DET
admet-159	336	8	manuscript	manuscript	NOUN
admet-159	336	9	.	.	PUNCT
admet-159	337	1	all	all	DET
admet-159	337	2	authors	author	NOUN
admet-159	337	3	have	have	AUX
admet-159	337	4	read	read	VERB
admet-159	337	5	and	and	CCONJ
admet-159	337	6	approved	approve	VERB
admet-159	337	7	the	the	DET
admet-159	337	8	final	final	ADJ
admet-159	337	9	version	version	NOUN
admet-159	337	10	of	of	ADP
admet-159	337	11	the	the	DET
admet-159	337	12	manuscript	manuscript	NOUN
admet-159	337	13	.	.	PUNCT
admet-159	338	1	acknowledgements	acknowledgement	NOUN
admet-159	338	2	:	:	PUNCT
admet-159	338	3	this	this	DET
admet-159	338	4	research	research	NOUN
admet-159	338	5	was	be	AUX
admet-159	338	6	supported	support	VERB
admet-159	338	7	in	in	ADP
admet-159	338	8	part	part	NOUN
admet-159	338	9	by	by	ADP
admet-159	338	10	nih	nih	PROPN
admet-159	338	11	/	/	SYM
admet-159	338	12	national	national	PROPN
admet-159	338	13	institute	institute	PROPN
admet-159	338	14	of	of	ADP
admet-159	338	15	environmental	environmental	PROPN
admet-159	338	16	health	health	PROPN
admet-159	338	17	sciences	sciences	PROPN
admet-159	338	18	grants	grant	NOUN
admet-159	338	19	ro1	ro1	NOUN
admet-159	338	20	-	-	PUNCT
admet-159	338	21	es008146	es008146	PROPN
admet-159	338	22	-	-	PUNCT
admet-159	338	23	17	17	NUM
admet-159	338	24	.	.	PUNCT
admet-159	339	1	mr	mr	PROPN
admet-159	339	2	.	.	PROPN
admet-159	339	3	christopher	christopher	PROPN
admet-159	339	4	bates	bates	PROPN
admet-159	339	5	has	have	AUX
admet-159	339	6	been	be	AUX
admet-159	339	7	partially	partially	ADV
admet-159	339	8	supported	support	VERB
admet-159	339	9	by	by	ADP
admet-159	339	10	nih	nih	PROPN
admet-159	339	11	/	/	SYM
admet-159	339	12	niehs	niehs	PROPN
admet-159	339	13	promotion	promotion	NOUN
admet-159	339	14	of	of	ADP
admet-159	339	15	diversity	diversity	NOUN
admet-159	339	16	in	in	ADP
admet-159	339	17	health	health	NOUN
admet-159	339	18	-	-	PUNCT
admet-159	339	19	related	relate	VERB
admet-159	339	20	research	research	NOUN
admet-159	339	21	program	program	NOUN
admet-159	339	22	.	.	PUNCT
admet-159	340	1	references	reference	NOUN
admet-159	340	2	[	[	X
admet-159	340	3	1	1	NUM
admet-159	340	4	]	]	PUNCT
admet-159	340	5	f.	f.	PROPN
admet-159	340	6	kamel	kamel	PROPN
admet-159	340	7	,	,	PUNCT
admet-159	340	8	science	science	NOUN
admet-159	340	9	341	341	NUM
admet-159	340	10	(	(	PUNCT
admet-159	340	11	2013	2013	NUM
admet-159	340	12	)	)	PUNCT
admet-159	340	13	722	722	NUM
admet-159	340	14	-	-	SYM
admet-159	340	15	723	723	NUM
admet-159	340	16	.	.	PUNCT
admet-159	341	1	[	[	X
admet-159	341	2	2	2	NUM
admet-159	341	3	]	]	PUNCT
admet-159	341	4	p.	p.	NOUN
admet-159	341	5	auluck	auluck	PROPN
admet-159	341	6	,	,	PUNCT
admet-159	341	7	g.	g.	PROPN
admet-159	341	8	caraveo	caraveo	PROPN
admet-159	341	9	,	,	PUNCT
admet-159	341	10	s.	s.	PROPN
admet-159	341	11	lindquist	lindquist	PROPN
admet-159	341	12	,	,	PUNCT
admet-159	341	13	ann	ann	PROPN
admet-159	341	14	.	.	PROPN
admet-159	341	15	rev	rev	PROPN
admet-159	341	16	.	.	PROPN
admet-159	341	17	cell	cell	PROPN
admet-159	341	18	dev	dev	PROPN
admet-159	341	19	.	.	PUNCT
admet-159	342	1	biol	biol	PROPN
admet-159	342	2	.	.	PUNCT
admet-159	343	1	26	26	NUM
admet-159	343	2	(	(	PUNCT
admet-159	343	3	2010	2010	NUM
admet-159	343	4	)	)	PUNCT
admet-159	343	5	211	211	NUM
admet-159	343	6	-	-	SYM
admet-159	343	7	233	233	NUM
admet-159	343	8	.	.	PUNCT
admet-159	344	1	[	[	X
admet-159	344	2	3	3	X
admet-159	344	3	]	]	X
admet-159	344	4	d.f	d.f	PROPN
admet-159	344	5	.	.	PROPN
admet-159	344	6	clayton	clayton	PROPN
admet-159	344	7	,	,	PUNCT
admet-159	344	8	j.m	j.m	PROPN
admet-159	344	9	.	.	PROPN
admet-159	344	10	george	george	PROPN
admet-159	344	11	,	,	PUNCT
admet-159	344	12	j.	j.	PROPN
admet-159	344	13	neurosci	neurosci	PROPN
admet-159	344	14	.	.	PUNCT
admet-159	345	1	res	re	NOUN
admet-159	345	2	.	.	PUNCT
admet-159	346	1	58	58	NUM
admet-159	346	2	(	(	PUNCT
admet-159	346	3	1999	1999	NUM
admet-159	346	4	)	)	PUNCT
admet-159	346	5	120	120	NUM
admet-159	346	6	-	-	SYM
admet-159	346	7	129	129	NUM
admet-159	346	8	.	.	PUNCT
admet-159	347	1	[	[	X
admet-159	347	2	4	4	X
admet-159	347	3	]	]	X
admet-159	347	4	d.	d.	PROPN
admet-159	347	5	murphy	murphy	PROPN
admet-159	347	6	,	,	PUNCT
admet-159	347	7	s.m	s.m	PROPN
admet-159	347	8	.	.	PROPN
admet-159	347	9	rueter	rueter	PROPN
admet-159	347	10	,	,	PUNCT
admet-159	347	11	j.q	j.q	PROPN
admet-159	347	12	.	.	PROPN
admet-159	347	13	trojanowski	trojanowski	PROPN
admet-159	347	14	,	,	PUNCT
admet-159	347	15	v.m.y	v.m.y	PROPN
admet-159	347	16	.	.	PUNCT
admet-159	347	17	lee	lee	PROPN
admet-159	347	18	,	,	PUNCT
admet-159	347	19	j.	j.	PROPN
admet-159	347	20	neurosci	neurosci	PROPN
admet-159	347	21	.	.	PUNCT
admet-159	348	1	20	20	NUM
admet-159	348	2	(	(	PUNCT
admet-159	348	3	2000	2000	NUM
admet-159	348	4	)	)	PUNCT
admet-159	348	5	3214	3214	NUM
admet-159	348	6	-	-	SYM
admet-159	348	7	3220	3220	NUM
admet-159	348	8	.	.	PUNCT
admet-159	349	1	[	[	X
admet-159	349	2	5	5	NUM
admet-159	349	3	]	]	SYM
admet-159	349	4	r.g	r.g	PROPN
admet-159	349	5	.	.	PROPN
admet-159	349	6	perez	perez	PROPN
admet-159	349	7	,	,	PUNCT
admet-159	349	8	j.c	j.c	PROPN
admet-159	349	9	.	.	PROPN
admet-159	349	10	waymire	waymire	PROPN
admet-159	349	11	,	,	PUNCT
admet-159	349	12	e.	e.	PROPN
admet-159	349	13	lin	lin	PROPN
admet-159	349	14	,	,	PUNCT
admet-159	349	15	j.j	j.j	PROPN
admet-159	349	16	.	.	PROPN
admet-159	349	17	liu	liu	PROPN
admet-159	349	18	,	,	PUNCT
admet-159	349	19	f.	f.	PROPN
admet-159	349	20	guo	guo	PROPN
admet-159	349	21	,	,	PUNCT
admet-159	349	22	m.j	m.j	PROPN
admet-159	349	23	.	.	PROPN
admet-159	349	24	zigmond	zigmond	PROPN
admet-159	349	25	,	,	PUNCT
admet-159	349	26	j.	j.	PROPN
admet-159	349	27	neurosci	neurosci	PROPN
admet-159	349	28	.	.	PUNCT
admet-159	350	1	22	22	NUM
admet-159	350	2	(	(	PUNCT
admet-159	350	3	2002	2002	NUM
admet-159	350	4	)	)	PUNCT
admet-159	350	5	3090	3090	NUM
admet-159	350	6	-	-	SYM
admet-159	350	7	3099	3099	NUM
admet-159	350	8	.	.	PUNCT
admet-159	351	1	[	[	X
admet-159	351	2	6	6	NUM
admet-159	351	3	]	]	PUNCT
admet-159	351	4	j.	j.	PROPN
admet-159	351	5	burré	burré	PROPN
admet-159	351	6	,	,	PUNCT
admet-159	351	7	m.	m.	NOUN
admet-159	351	8	sharma	sharma	PROPN
admet-159	351	9	,	,	PUNCT
admet-159	351	10	t.	t.	PROPN
admet-159	351	11	tsetsenis	tsetsenis	PROPN
admet-159	351	12	,	,	PUNCT
admet-159	351	13	v.	v.	PROPN
admet-159	351	14	buchman	buchman	PROPN
admet-159	351	15	,	,	PUNCT
admet-159	351	16	m.	m.	PROPN
admet-159	351	17	etherton	etherton	PROPN
admet-159	351	18	,	,	PUNCT
admet-159	351	19	t.c	t.c	PROPN
admet-159	351	20	.	.	PROPN
admet-159	351	21	südhof	südhof	PROPN
admet-159	351	22	,	,	PUNCT
admet-159	351	23	science	science	NOUN
admet-159	351	24	329	329	NUM
admet-159	351	25	(	(	PUNCT
admet-159	351	26	2010	2010	NUM
admet-159	351	27	)	)	PUNCT
admet-159	351	28	16631667	16631667	NUM
admet-159	351	29	.	.	PUNCT
admet-159	352	1	[	[	X
admet-159	352	2	7	7	X
admet-159	352	3	]	]	X
admet-159	352	4	s.l	s.l	PROPN
admet-159	352	5	.	.	PROPN
admet-159	352	6	gordon	gordon	PROPN
admet-159	352	7	,	,	PUNCT
admet-159	352	8	m.a	m.a	PROPN
admet-159	352	9	.	.	PROPN
admet-159	352	10	cousin	cousin	PROPN
admet-159	352	11	,	,	PUNCT
admet-159	352	12	traffic	traffic	NOUN
admet-159	352	13	15	15	NUM
admet-159	352	14	(	(	PUNCT
admet-159	352	15	2014	2014	NUM
admet-159	352	16	)	)	PUNCT
admet-159	352	17	245	245	NUM
admet-159	352	18	-	-	SYM
admet-159	352	19	254	254	NUM
admet-159	352	20	.	.	PUNCT
admet-159	353	1	[	[	X
admet-159	353	2	8	8	NUM
admet-159	353	3	]	]	X
admet-159	353	4	h.	h.	PROPN
admet-159	353	5	lee	lee	PROPN
admet-159	353	6	,	,	PUNCT
admet-159	353	7	s.	s.	PROPN
admet-159	353	8	patel	patel	PROPN
admet-159	353	9	,	,	PUNCT
admet-159	353	10	s.	s.	PROPN
admet-159	353	11	lee	lee	PROPN
admet-159	353	12	,	,	PUNCT
admet-159	353	13	j.	j.	PROPN
admet-159	353	14	neurosci	neurosci	PROPN
admet-159	353	15	.	.	PUNCT
admet-159	354	1	2005	2005	NUM
admet-159	354	2	.	.	PUNCT
admet-159	355	1	25	25	NUM
admet-159	355	2	(	(	PUNCT
admet-159	355	3	2005	2005	NUM
admet-159	355	4	)	)	PUNCT
admet-159	355	5	6016	6016	NUM
admet-159	355	6	-	-	SYM
admet-159	355	7	6024	6024	NUM
admet-159	355	8	.	.	PUNCT
admet-159	356	1	[	[	X
admet-159	356	2	9	9	NUM
admet-159	356	3	]	]	X
admet-159	356	4	h.	h.	PROPN
admet-159	356	5	lee	lee	PROPN
admet-159	356	6	,	,	PUNCT
admet-159	356	7	e.	e.	PROPN
admet-159	356	8	cho	cho	PROPN
admet-159	356	9	,	,	PUNCT
admet-159	356	10	k.w	k.w	PROPN
admet-159	356	11	.	.	PROPN
admet-159	356	12	lee	lee	PROPN
admet-159	356	13	,	,	PUNCT
admet-159	356	14	j.	j.	PROPN
admet-159	356	15	kim	kim	PROPN
admet-159	356	16	,	,	PUNCT
admet-159	356	17	s.	s.	PROPN
admet-159	356	18	cho	cho	PROPN
admet-159	356	19	,	,	PUNCT
admet-159	356	20	s.	s.	PROPN
admet-159	356	21	lee	lee	PROPN
admet-159	356	22	,	,	PUNCT
admet-159	356	23	exp	exp	PROPN
admet-159	356	24	.	.	PROPN
admet-159	356	25	&	&	CCONJ
admet-159	356	26	mol	mol	PROPN
admet-159	356	27	.	.	PROPN
admet-159	356	28	med	med	PROPN
admet-159	356	29	.	.	PUNCT
admet-159	357	1	45	45	NUM
admet-159	357	2	(	(	PUNCT
admet-159	357	3	2013	2013	NUM
admet-159	357	4	)	)	PUNCT
admet-159	357	5	1	1	NUM
admet-159	357	6	-	-	SYM
admet-159	357	7	9	9	NUM
admet-159	357	8	.	.	PUNCT
admet-159	358	1	[	[	X
admet-159	358	2	10	10	NUM
admet-159	358	3	]	]	X
admet-159	358	4	w.	w.	PROPN
admet-159	358	5	zheng	zheng	PROPN
admet-159	358	6	,	,	PUNCT
admet-159	358	7	m.	m.	NOUN
admet-159	358	8	aschner	aschner	NOUN
admet-159	358	9	,	,	PUNCT
admet-159	358	10	j.f	j.f	PROPN
admet-159	358	11	.	.	PROPN
admet-159	358	12	ghersi	ghersi	NOUN
admet-159	358	13	-	-	PUNCT
admet-159	358	14	egea	egea	NOUN
admet-159	358	15	,	,	PUNCT
admet-159	358	16	toxicol	toxicol	PROPN
admet-159	358	17	.	.	PUNCT
admet-159	359	1	appl	appl	PROPN
admet-159	359	2	.	.	PUNCT
admet-159	360	1	pharmacol	pharmacol	PROPN
admet-159	360	2	.	.	PUNCT
admet-159	361	1	192	192	NUM
admet-159	361	2	(	(	PUNCT
admet-159	361	3	2003	2003	NUM
admet-159	361	4	)	)	PUNCT
admet-159	361	5	1	1	NUM
admet-159	361	6	-	-	SYM
admet-159	361	7	11	11	NUM
admet-159	361	8	.	.	PUNCT
admet-159	362	1	[	[	X
admet-159	362	2	11	11	NUM
admet-159	362	3	]	]	X
admet-159	362	4	c.e	c.e	PROPN
admet-159	362	5	.	.	PROPN
admet-159	362	6	johansen	johansen	PROPN
admet-159	362	7	,	,	PUNCT
admet-159	362	8	j.a	j.a	PROPN
admet-159	362	9	.	.	PROPN
admet-159	362	10	duncan	duncan	PROPN
admet-159	362	11	,	,	PUNCT
admet-159	362	12	e.g.	e.g.	ADV
admet-159	362	13	stopa	stopa	NOUN
admet-159	362	14	,	,	PUNCT
admet-159	362	15	a.	a.	PROPN
admet-159	362	16	baird	baird	PROPN
admet-159	362	17	,	,	PUNCT
admet-159	362	18	pharma	pharma	PROPN
admet-159	362	19	.	.	PUNCT
admet-159	363	1	res	re	NOUN
admet-159	363	2	.	.	PUNCT
admet-159	364	1	22	22	NUM
admet-159	364	2	(	(	PUNCT
admet-159	364	3	2005	2005	NUM
admet-159	364	4	)	)	PUNCT
admet-159	364	5	1011	1011	NUM
admet-159	364	6	-	-	SYM
admet-159	364	7	1037	1037	NUM
admet-159	364	8	.	.	PUNCT
admet-159	365	1	bates	bates	PROPN
admet-159	365	2	et	et	PROPN
admet-159	365	3	al	al	PROPN
admet-159	365	4	.	.	PROPN
admet-159	365	5	admet	admet	PROPN
admet-159	365	6	&	&	CCONJ
admet-159	365	7	dmpk	dmpk	PROPN
admet-159	365	8	3(1	3(1	NUM
admet-159	365	9	)	)	PUNCT
admet-159	365	10	(	(	PUNCT
admet-159	365	11	2015	2015	NUM
admet-159	365	12	)	)	PUNCT
admet-159	365	13	15	15	NUM
admet-159	365	14	-	-	SYM
admet-159	365	15	33	33	NUM
admet-159	365	16	30	30	NUM
admet-159	365	17	[	[	X
admet-159	365	18	12	12	NUM
admet-159	365	19	]	]	PUNCT
admet-159	365	20	b.	b.	PROPN
admet-159	365	21	mollenhauer	mollenhauer	PROPN
admet-159	365	22	,	,	PUNCT
admet-159	365	23	e.	e.	PROPN
admet-159	365	24	trautmann	trautmann	PROPN
admet-159	365	25	,	,	PUNCT
admet-159	365	26	b.	b.	PROPN
admet-159	365	27	otte	otte	PROPN
admet-159	365	28	,	,	PUNCT
admet-159	365	29	j.	j.	PROPN
admet-159	365	30	ng	ng	PROPN
admet-159	365	31	,	,	PUNCT
admet-159	365	32	a.	a.	PROPN
admet-159	365	33	spreer	spreer	PROPN
admet-159	365	34	,	,	PUNCT
admet-159	365	35	p.	p.	NOUN
admet-159	365	36	lange	lange	PROPN
admet-159	365	37	,	,	PUNCT
admet-159	365	38	f.	f.	PROPN
admet-159	365	39	sixel	sixel	PROPN
admet-159	365	40	-	-	PUNCT
admet-159	365	41	döring	döring	NOUN
admet-159	365	42	,	,	PUNCT
admet-159	365	43	m.	m.	NOUN
admet-159	365	44	hakimi	hakimi	PROPN
admet-159	365	45	,	,	PUNCT
admet-159	365	46	j.	j.	PROPN
admet-159	365	47	vonsattel	vonsattel	PROPN
admet-159	365	48	,	,	PUNCT
admet-159	365	49	r.	r.	PROPN
admet-159	365	50	nussbaum	nussbaum	PROPN
admet-159	365	51	,	,	PUNCT
admet-159	365	52	c.	c.	PROPN
admet-159	365	53	trenkwalder	trenkwalder	PROPN
admet-159	365	54	,	,	PUNCT
admet-159	365	55	m.g	m.g	PROPN
admet-159	365	56	.	.	PROPN
admet-159	365	57	schlossmacher	schlossmacher	PROPN
admet-159	365	58	,	,	PUNCT
admet-159	365	59	j.	j.	PROPN
admet-159	365	60	neural	neural	PROPN
admet-159	365	61	.	.	PUNCT
admet-159	366	1	transm	transm	PROPN
admet-159	366	2	.	.	PUNCT
admet-159	367	1	119	119	NUM
admet-159	367	2	(	(	PUNCT
admet-159	367	3	2012	2012	NUM
admet-159	367	4	)	)	PUNCT
admet-159	367	5	739746	739746	NUM
admet-159	367	6	.	.	PUNCT
admet-159	368	1	[	[	X
admet-159	368	2	13	13	NUM
admet-159	368	3	]	]	PUNCT
admet-159	368	4	z.	z.	PROPN
admet-159	368	5	hong	hong	PROPN
admet-159	368	6	,	,	PUNCT
admet-159	368	7	m.	m.	PROPN
admet-159	368	8	shi	shi	PROPN
admet-159	368	9	,	,	PUNCT
admet-159	368	10	k.a	k.a	PROPN
admet-159	368	11	.	.	PROPN
admet-159	368	12	chung	chung	PROPN
admet-159	368	13	,	,	PUNCT
admet-159	368	14	j.f	j.f	PROPN
admet-159	368	15	.	.	PROPN
admet-159	368	16	quinn	quinn	PROPN
admet-159	368	17	,	,	PUNCT
admet-159	368	18	e.r	e.r	PROPN
admet-159	368	19	.	.	PROPN
admet-159	368	20	peskind	peskind	PROPN
admet-159	368	21	,	,	PUNCT
admet-159	368	22	d.	d.	PROPN
admet-159	368	23	galasko	galasko	PROPN
admet-159	368	24	,	,	PUNCT
admet-159	368	25	j.	j.	PROPN
admet-159	368	26	janković	janković	PROPN
admet-159	368	27	,	,	PUNCT
admet-159	368	28	c.p	c.p	PROPN
admet-159	368	29	.	.	PROPN
admet-159	368	30	zabetian	zabetian	PROPN
admet-159	368	31	,	,	PUNCT
admet-159	368	32	j.b	j.b	PROPN
admet-159	368	33	.	.	PROPN
admet-159	368	34	leverenz	leverenz	PROPN
admet-159	368	35	,	,	PUNCT
admet-159	368	36	g.	g.	PROPN
admet-159	368	37	baird	baird	PROPN
admet-159	368	38	,	,	PUNCT
admet-159	368	39	t.j	t.j	PROPN
admet-159	368	40	.	.	PROPN
admet-159	368	41	montine	montine	PROPN
admet-159	368	42	,	,	PUNCT
admet-159	368	43	a.m.	a.m.	PROPN
admet-159	368	44	hancock	hancock	PROPN
admet-159	368	45	,	,	PUNCT
admet-159	368	46	h.	h.	PROPN
admet-159	368	47	hwang	hwang	PROPN
admet-159	368	48	,	,	PUNCT
admet-159	368	49	c.	c.	PROPN
admet-159	368	50	pan	pan	PROPN
admet-159	368	51	,	,	PUNCT
admet-159	368	52	j.	j.	PROPN
admet-159	368	53	bradner	bradner	PROPN
admet-159	368	54	,	,	PUNCT
admet-159	368	55	u.j	u.j	PROPN
admet-159	368	56	.	.	PROPN
admet-159	368	57	kang	kang	PROPN
admet-159	368	58	,	,	PUNCT
admet-159	368	59	p.h	p.h	PROPN
admet-159	368	60	.	.	PROPN
admet-159	368	61	jensen	jensen	PROPN
admet-159	368	62	,	,	PUNCT
admet-159	368	63	j.	j.	PROPN
admet-159	368	64	zhang	zhang	PROPN
admet-159	368	65	,	,	PUNCT
admet-159	368	66	brain	brain	VERB
admet-159	368	67	133	133	NUM
admet-159	368	68	(	(	PUNCT
admet-159	368	69	2010	2010	NUM
admet-159	368	70	)	)	PUNCT
admet-159	368	71	713	713	NUM
admet-159	368	72	-	-	SYM
admet-159	368	73	726	726	NUM
admet-159	368	74	.	.	PUNCT
admet-159	369	1	[	[	X
admet-159	369	2	14	14	NUM
admet-159	369	3	]	]	X
admet-159	369	4	p.g	p.g	PROPN
admet-159	369	5	.	.	PROPN
admet-159	369	6	foulds	fould	NOUN
admet-159	369	7	,	,	PUNCT
admet-159	369	8	p.	p.	PROPN
admet-159	369	9	diggle	diggle	PROPN
admet-159	369	10	,	,	PUNCT
admet-159	369	11	j.d	j.d	PROPN
admet-159	369	12	.	.	PROPN
admet-159	369	13	mitchell	mitchell	PROPN
admet-159	369	14	,	,	PUNCT
admet-159	369	15	a.	a.	PROPN
admet-159	369	16	parker	parker	PROPN
admet-159	369	17	,	,	PUNCT
admet-159	369	18	m.	m.	PROPN
admet-159	369	19	hasegawa	hasegawa	PROPN
admet-159	369	20	,	,	PUNCT
admet-159	369	21	m.	m.	PROPN
admet-159	369	22	masuda	masuda	PROPN
admet-159	369	23	-	-	PUNCT
admet-159	369	24	suzukake	suzukake	PROPN
admet-159	369	25	,	,	PUNCT
admet-159	369	26	d.m.a	d.m.a	NOUN
admet-159	369	27	.	.	PUNCT
admet-159	370	1	mann	mann	PROPN
admet-159	370	2	,	,	PUNCT
admet-159	370	3	d.	d.	PROPN
admet-159	370	4	allsop	allsop	PROPN
admet-159	370	5	.	.	PUNCT
admet-159	371	1	sci	sci	PROPN
admet-159	371	2	.	.	PROPN
admet-159	371	3	rep	rep	PROPN
admet-159	371	4	.	.	PROPN
admet-159	371	5	3	3	NUM
admet-159	371	6	(	(	PUNCT
admet-159	371	7	2013	2013	NUM
admet-159	371	8	)	)	PUNCT
admet-159	371	9	2540	2540	NUM
admet-159	371	10	.	.	PUNCT
admet-159	372	1	[	[	X
admet-159	372	2	15	15	NUM
admet-159	372	3	]	]	X
admet-159	372	4	b.	b.	PROPN
admet-159	372	5	mollenhauer	mollenhauer	PROPN
admet-159	372	6	,	,	PUNCT
admet-159	372	7	e.	e.	PROPN
admet-159	372	8	trautmann	trautmann	PROPN
admet-159	372	9	,	,	PUNCT
admet-159	372	10	p.	p.	PROPN
admet-159	372	11	taylor	taylor	PROPN
admet-159	372	12	,	,	PUNCT
admet-159	372	13	p.	p.	PROPN
admet-159	372	14	manniger	manniger	PROPN
admet-159	372	15	,	,	PUNCT
admet-159	372	16	f.	f.	PROPN
admet-159	372	17	sixel	sixel	PROPN
admet-159	372	18	-	-	PUNCT
admet-159	372	19	döring	döring	NOUN
admet-159	372	20	,	,	PUNCT
admet-159	372	21	j.	j.	PROPN
admet-159	372	22	ebentheuer	ebentheuer	PROPN
admet-159	372	23	,	,	PUNCT
admet-159	372	24	c.	c.	PROPN
admet-159	372	25	trenkwalder	trenkwalder	PROPN
admet-159	372	26	,	,	PUNCT
admet-159	372	27	m.g	m.g	PROPN
admet-159	372	28	.	.	PROPN
admet-159	372	29	schlossmacher	schlossmacher	PROPN
admet-159	372	30	,	,	PUNCT
admet-159	372	31	j.	j.	PROPN
admet-159	372	32	neurosci	neurosci	PROPN
admet-159	372	33	.	.	PUNCT
admet-159	373	1	lett	lett	PROPN
admet-159	373	2	.	.	PUNCT
admet-159	374	1	532	532	NUM
admet-159	374	2	(	(	PUNCT
admet-159	374	3	2013	2013	NUM
admet-159	374	4	)	)	PUNCT
admet-159	374	5	44	44	NUM
admet-159	374	6	-	-	SYM
admet-159	374	7	48	48	NUM
admet-159	374	8	.	.	PUNCT
admet-159	375	1	[	[	X
admet-159	375	2	16	16	NUM
admet-159	375	3	]	]	X
admet-159	375	4	h.	h.	PROPN
admet-159	375	5	lee	lee	PROPN
admet-159	375	6	,	,	PUNCT
admet-159	375	7	j.	j.	PROPN
admet-159	375	8	suk	suk	PROPN
admet-159	375	9	,	,	PUNCT
admet-159	375	10	e.	e.	PROPN
admet-159	375	11	bae	bae	PROPN
admet-159	375	12	,	,	PUNCT
admet-159	375	13	j.	j.	PROPN
admet-159	375	14	lee	lee	PROPN
admet-159	375	15	,	,	PUNCT
admet-159	375	16	s.r	s.r	PROPN
admet-159	375	17	:	:	SYM
admet-159	375	18	paik	paik	NOUN
admet-159	375	19	,	,	PUNCT
admet-159	375	20	s.	s.	PROPN
admet-159	375	21	lee	lee	PROPN
admet-159	375	22	,	,	PUNCT
admet-159	375	23	int	int	PROPN
admet-159	375	24	.	.	PUNCT
admet-159	376	1	j.	j.	PROPN
admet-159	376	2	biochem	biochem	PROPN
admet-159	376	3	.	.	PUNCT
admet-159	376	4	&	&	CCONJ
admet-159	376	5	cell	cell	PROPN
admet-159	376	6	bio	bio	PROPN
admet-159	376	7	.	.	PROPN
admet-159	376	8	40	40	NUM
admet-159	376	9	(	(	PUNCT
admet-159	376	10	2008	2008	NUM
admet-159	376	11	)	)	PUNCT
admet-159	376	12	1835	1835	NUM
admet-159	376	13	-	-	SYM
admet-159	376	14	849	849	NUM
admet-159	376	15	.	.	PUNCT
admet-159	377	1	[	[	X
admet-159	377	2	17	17	NUM
admet-159	377	3	]	]	X
admet-159	377	4	p.	p.	NOUN
admet-159	377	5	desplats	desplats	PROPN
admet-159	377	6	,	,	PUNCT
admet-159	377	7	h.	h.	PROPN
admet-159	377	8	lee	lee	PROPN
admet-159	377	9	,	,	PUNCT
admet-159	377	10	e.	e.	PROPN
admet-159	377	11	bae	bae	PROPN
admet-159	377	12	,	,	PUNCT
admet-159	377	13	c.	c.	PROPN
admet-159	377	14	patrick	patrick	PROPN
admet-159	377	15	,	,	PUNCT
admet-159	377	16	e.	e.	PROPN
admet-159	377	17	rockenstein	rockenstein	PROPN
admet-159	377	18	,	,	PUNCT
admet-159	377	19	l.	l.	PROPN
admet-159	377	20	crews	crews	PROPN
admet-159	377	21	,	,	PUNCT
admet-159	377	22	b.	b.	PROPN
admet-159	377	23	spencer	spencer	PROPN
admet-159	377	24	,	,	PUNCT
admet-159	377	25	e.	e.	PROPN
admet-159	377	26	masliah	masliah	PROPN
admet-159	377	27	,	,	PUNCT
admet-159	377	28	s.	s.	PROPN
admet-159	377	29	lee	lee	PROPN
admet-159	377	30	,	,	PUNCT
admet-159	377	31	pnas	pnas	PROPN
admet-159	377	32	106	106	NUM
admet-159	377	33	(	(	PUNCT
admet-159	377	34	2009	2009	NUM
admet-159	377	35	)	)	PUNCT
admet-159	377	36	13010	13010	NUM
admet-159	377	37	-	-	SYM
admet-159	377	38	13015	13015	NUM
admet-159	377	39	.	.	PUNCT
admet-159	378	1	[	[	X
admet-159	378	2	18	18	NUM
admet-159	378	3	]	]	PUNCT
admet-159	378	4	m.	m.	NOUN
admet-159	378	5	wennstrom	wennstrom	NOUN
admet-159	378	6	,	,	PUNCT
admet-159	378	7	y.	y.	PROPN
admet-159	378	8	surova	surova	PROPN
admet-159	378	9	,	,	PUNCT
admet-159	378	10	s.	s.	PROPN
admet-159	378	11	hall	hall	PROPN
admet-159	378	12	,	,	PUNCT
admet-159	378	13	c.	c.	PROPN
admet-159	378	14	nilsson	nilsson	PROPN
admet-159	378	15	,	,	PUNCT
admet-159	378	16	l.	l.	PROPN
admet-159	378	17	minthon	minthon	PROPN
admet-159	378	18	,	,	PUNCT
admet-159	378	19	f.	f.	PROPN
admet-159	378	20	boström	boström	PROPN
admet-159	378	21	,	,	PUNCT
admet-159	378	22	o.	o.	PROPN
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admet-159	378	24	,	,	PUNCT
admet-159	378	25	h.m	h.m	PROPN
admet-159	378	26	.	.	PROPN
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admet-159	378	28	,	,	PUNCT
admet-159	378	29	plos	plos	PROPN
admet-159	378	30	one	one	NUM
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admet-159	378	32	(	(	PUNCT
admet-159	378	33	2013	2013	NUM
admet-159	378	34	)	)	PUNCT
admet-159	378	35	e53250	e53250	PROPN
admet-159	378	36	.	.	PUNCT
admet-159	379	1	[	[	X
admet-159	379	2	19	19	NUM
admet-159	379	3	]	]	X
admet-159	379	4	c.a	c.a	PROPN
admet-159	379	5	.	.	PROPN
admet-159	379	6	bates	bates	PROPN
admet-159	379	7	,	,	PUNCT
admet-159	379	8	w.	w.	PROPN
admet-159	379	9	zheng	zheng	PROPN
admet-159	379	10	,	,	PUNCT
admet-159	379	11	fluids	fluid	NOUN
admet-159	379	12	barriers	barrier	NOUN
admet-159	379	13	cns	cns	PROPN
admet-159	379	14	,	,	PUNCT
admet-159	379	15	2014	2014	NUM
admet-159	379	16	.	.	PUNCT
admet-159	380	1	(	(	PUNCT
admet-159	380	2	in	in	ADP
admet-159	380	3	press	press	NOUN
admet-159	380	4	)	)	PUNCT
admet-159	380	5	.	.	PUNCT
admet-159	381	1	[	[	X
admet-159	381	2	20	20	NUM
admet-159	381	3	]	]	X
admet-159	381	4	m.r	m.r	PROPN
admet-159	381	5	.	.	PROPN
admet-159	381	6	dewitt	dewitt	PROPN
admet-159	381	7	,	,	PUNCT
admet-159	381	8	p.	p.	PROPN
admet-159	381	9	chen	chen	PROPN
admet-159	381	10	,	,	PUNCT
admet-159	381	11	m.	m.	NOUN
admet-159	381	12	aschner	aschner	NOUN
admet-159	381	13	,	,	PUNCT
admet-159	381	14	biochem	biochem	PROPN
admet-159	381	15	.	.	PUNCT
admet-159	382	1	biophys	biophy	NOUN
admet-159	382	2	.	.	PUNCT
admet-159	383	1	res	re	NOUN
admet-159	383	2	.	.	PUNCT
admet-159	384	1	commun	commun	PROPN
admet-159	384	2	.	.	PUNCT
admet-159	385	1	432	432	NUM
admet-159	385	2	(	(	PUNCT
admet-159	385	3	2013	2013	NUM
admet-159	385	4	)	)	PUNCT
admet-159	385	5	1	1	NUM
admet-159	385	6	-	-	SYM
admet-159	385	7	4	4	NUM
admet-159	385	8	.	.	PUNCT
admet-159	386	1	[	[	X
admet-159	386	2	21	21	NUM
admet-159	386	3	]	]	X
admet-159	386	4	d.m	d.m	PROPN
admet-159	386	5	.	.	PUNCT
admet-159	386	6	cowan	cowan	PROPN
admet-159	386	7	,	,	PUNCT
admet-159	386	8	w.	w.	PROPN
admet-159	386	9	zheng	zheng	PROPN
admet-159	386	10	,	,	PUNCT
admet-159	386	11	y.	y.	PROPN
admet-159	386	12	zou	zou	PROPN
admet-159	386	13	,	,	PUNCT
admet-159	386	14	x.	x.	PROPN
admet-159	386	15	shi	shi	PROPN
admet-159	386	16	,	,	PUNCT
admet-159	386	17	j.	j.	PROPN
admet-159	386	18	chen	chen	PROPN
admet-159	386	19	,	,	PUNCT
admet-159	386	20	f.	f.	PROPN
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admet-159	386	22	,	,	PUNCT
admet-159	386	23	q.	q.	PROPN
admet-159	386	24	fan	fan	PROPN
admet-159	386	25	,	,	PUNCT
admet-159	386	26	neurotoxicology	neurotoxicology	NOUN
admet-159	386	27	30	30	NUM
admet-159	386	28	(	(	PUNCT
admet-159	386	29	2009	2009	NUM
admet-159	386	30	)	)	PUNCT
admet-159	386	31	1214	1214	NUM
admet-159	386	32	-	-	SYM
admet-159	386	33	1222	1222	NUM
admet-159	386	34	.	.	PUNCT
admet-159	387	1	[	[	X
admet-159	387	2	22	22	NUM
admet-159	387	3	]	]	X
admet-159	387	4	j.	j.	PROPN
admet-159	387	5	bornhorst	bornhorst	PROPN
admet-159	387	6	,	,	PUNCT
admet-159	387	7	c.a	c.a	PROPN
admet-159	387	8	.	.	PROPN
admet-159	387	9	wehe	wehe	PROPN
admet-159	387	10	,	,	PUNCT
admet-159	387	11	s.	s.	PROPN
admet-159	387	12	hüwel	hüwel	PROPN
admet-159	387	13	,	,	PUNCT
admet-159	387	14	u.	u.	PROPN
admet-159	387	15	karst	karst	PROPN
admet-159	387	16	,	,	PUNCT
admet-159	387	17	h.j	h.j	PROPN
admet-159	387	18	.	.	PROPN
admet-159	387	19	galla	galla	PROPN
admet-159	387	20	,	,	PUNCT
admet-159	387	21	t.	t.	NOUN
admet-159	387	22	schwerdtle	schwerdtle	PROPN
admet-159	387	23	,	,	PUNCT
admet-159	387	24	j.	j.	PROPN
admet-159	387	25	biol	biol	PROPN
admet-159	387	26	.	.	PUNCT
admet-159	388	1	chem	chem	NOUN
admet-159	388	2	.	.	PUNCT
admet-159	389	1	287	287	NUM
admet-159	389	2	(	(	PUNCT
admet-159	389	3	2012	2012	NUM
admet-159	389	4	)	)	PUNCT
admet-159	389	5	17140	17140	NUM
admet-159	389	6	-	-	SYM
admet-159	389	7	17151	17151	NUM
admet-159	389	8	.	.	PUNCT
admet-159	390	1	[	[	X
admet-159	390	2	23	23	NUM
admet-159	390	3	]	]	X
admet-159	390	4	d.p	d.p	PROPN
admet-159	390	5	.	.	PROPN
admet-159	390	6	perl	perl	PROPN
admet-159	390	7	,	,	PUNCT
admet-159	390	8	c.w	c.w	PROPN
admet-159	390	9	.	.	PROPN
admet-159	390	10	olanow	olanow	PROPN
admet-159	390	11	,	,	PUNCT
admet-159	390	12	j.	j.	PROPN
admet-159	390	13	neuropathol	neuropathol	PROPN
admet-159	390	14	.	.	PUNCT
admet-159	391	1	exp	exp	PROPN
admet-159	391	2	.	.	PUNCT
admet-159	391	3	neuro	neuro	PROPN
admet-159	391	4	.	.	PUNCT
admet-159	392	1	66	66	NUM
admet-159	392	2	(	(	PUNCT
admet-159	392	3	2007	2007	NUM
admet-159	392	4	)	)	PUNCT
admet-159	392	5	675	675	NUM
admet-159	392	6	-	-	SYM
admet-159	392	7	682	682	NUM
admet-159	392	8	.	.	PUNCT
admet-159	393	1	[	[	X
admet-159	393	2	24	24	NUM
admet-159	393	3	]	]	X
admet-159	393	4	j.p	j.p	PROPN
admet-159	393	5	.	.	PROPN
admet-159	393	6	covy	covy	PROPN
admet-159	393	7	,	,	PUNCT
admet-159	393	8	b.i	b.i	PROPN
admet-159	393	9	.	.	PROPN
admet-159	393	10	giasson	giasson	PROPN
admet-159	393	11	,	,	PUNCT
admet-159	393	12	neurotox	neurotox	NOUN
admet-159	393	13	32	32	NUM
admet-159	393	14	(	(	PUNCT
admet-159	393	15	2011	2011	NUM
admet-159	393	16	)	)	PUNCT
admet-159	393	17	622	622	NUM
admet-159	393	18	-	-	SYM
admet-159	393	19	629	629	NUM
admet-159	393	20	.	.	PUNCT
admet-159	394	1	[	[	X
admet-159	394	2	25	25	NUM
admet-159	394	3	]	]	X
admet-159	394	4	g.	g.	PROPN
admet-159	394	5	robison	robison	PROPN
admet-159	394	6	,	,	PUNCT
admet-159	394	7	t.	t.	PROPN
admet-159	394	8	zakharova	zakharova	PROPN
admet-159	394	9	,	,	PUNCT
admet-159	394	10	s.	s.	PROPN
admet-159	394	11	fu	fu	PROPN
admet-159	394	12	,	,	PUNCT
admet-159	394	13	w.	w.	PROPN
admet-159	394	14	jiang	jiang	PROPN
admet-159	394	15	,	,	PUNCT
admet-159	394	16	r.	r.	PROPN
admet-159	394	17	fulper	fulper	PROPN
admet-159	394	18	,	,	PUNCT
admet-159	394	19	r.	r.	PROPN
admet-159	394	20	barrea	barrea	PROPN
admet-159	394	21	,	,	PUNCT
admet-159	394	22	m.a	m.a	PROPN
admet-159	394	23	.	.	PROPN
admet-159	394	24	marcus	marcus	PROPN
admet-159	394	25	,	,	PUNCT
admet-159	394	26	w.	w.	PROPN
admet-159	394	27	zheng	zheng	PROPN
admet-159	394	28	,	,	PUNCT
admet-159	394	29	y.	y.	PROPN
admet-159	394	30	pushkar	pushkar	PROPN
admet-159	394	31	,	,	PUNCT
admet-159	394	32	plos	plos	PROPN
admet-159	394	33	one	one	NUM
admet-159	394	34	7	7	NUM
admet-159	394	35	(	(	PUNCT
admet-159	394	36	2012	2012	NUM
admet-159	394	37	)	)	PUNCT
admet-159	394	38	e48899	e48899	VERB
admet-159	395	1	[	[	X
admet-159	395	2	26	26	NUM
admet-159	395	3	]	]	X
admet-159	395	4	t.r	t.r	PROPN
admet-159	395	5	.	.	PROPN
admet-159	395	6	guilarte	guilarte	PROPN
admet-159	395	7	,	,	PUNCT
admet-159	395	8	m.k	m.k	PROPN
admet-159	395	9	.	.	PUNCT
admet-159	395	10	chen	chen	PROPN
admet-159	395	11	,	,	PUNCT
admet-159	395	12	neurotox	neurotox	NOUN
admet-159	395	13	28	28	NUM
admet-159	395	14	(	(	PUNCT
admet-159	395	15	2007	2007	NUM
admet-159	395	16	)	)	PUNCT
admet-159	395	17	1147	1147	NUM
admet-159	395	18	-	-	SYM
admet-159	395	19	1152	1152	NUM
admet-159	395	20	.	.	PUNCT
admet-159	396	1	[	[	X
admet-159	396	2	27	27	NUM
admet-159	396	3	]	]	PUNCT
admet-159	396	4	x.	x.	PROPN
admet-159	396	5	wang	wang	PROPN
admet-159	396	6	,	,	PUNCT
admet-159	396	7	g.j	g.j	PROPN
admet-159	396	8	.	.	PROPN
admet-159	396	9	li	li	PROPN
admet-159	396	10	,	,	PUNCT
admet-159	396	11	w.	w.	PROPN
admet-159	396	12	zheng	zheng	PROPN
admet-159	396	13	,	,	PUNCT
admet-159	396	14	exp	exp	NOUN
admet-159	396	15	.	.	PUNCT
admet-159	397	1	biol	biol	PROPN
admet-159	397	2	.	.	PUNCT
admet-159	398	1	med	med	PROPN
admet-159	398	2	.	.	PUNCT
admet-159	399	1	233	233	NUM
admet-159	399	2	(	(	PUNCT
admet-159	399	3	2008	2008	NUM
admet-159	399	4	)	)	PUNCT
admet-159	399	5	1561	1561	NUM
admet-159	399	6	-	-	SYM
admet-159	399	7	1571	1571	NUM
admet-159	399	8	.	.	PUNCT
admet-159	400	1	[	[	X
admet-159	400	2	28	28	NUM
admet-159	400	3	]	]	X
admet-159	400	4	u.	u.	PROPN
admet-159	400	5	dydak	dydak	PROPN
admet-159	400	6	,	,	PUNCT
admet-159	400	7	y.	y.	PROPN
admet-159	400	8	jiang	jiang	PROPN
admet-159	400	9	,	,	PUNCT
admet-159	400	10	l.	l.	PROPN
admet-159	400	11	long	long	PROPN
admet-159	400	12	,	,	PUNCT
admet-159	400	13	h.	h.	PROPN
admet-159	400	14	zhu	zhu	PROPN
admet-159	400	15	,	,	PUNCT
admet-159	400	16	j.	j.	PROPN
admet-159	400	17	chen	chen	PROPN
admet-159	400	18	,	,	PUNCT
admet-159	400	19	w.	w.	PROPN
admet-159	400	20	li	li	PROPN
admet-159	400	21	,	,	PUNCT
admet-159	400	22	r.a.e	r.a.e	PROPN
admet-159	400	23	.	.	PUNCT
admet-159	401	1	edden	edden	PROPN
admet-159	401	2	,	,	PUNCT
admet-159	401	3	s.	s.	PROPN
admet-159	401	4	hu	hu	PROPN
admet-159	401	5	,	,	PUNCT
admet-159	401	6	x.	x.	PROPN
admet-159	401	7	fu	fu	PROPN
admet-159	401	8	,	,	PUNCT
admet-159	401	9	z.	z.	PROPN
admet-159	401	10	long	long	PROPN
admet-159	401	11	,	,	PUNCT
admet-159	401	12	x.	x.	PROPN
admet-159	401	13	mo	mo	PROPN
admet-159	401	14	,	,	PUNCT
admet-159	401	15	d.	d.	PROPN
admet-159	401	16	meier	meier	PROPN
admet-159	401	17	,	,	PUNCT
admet-159	401	18	j.	j.	PROPN
admet-159	401	19	hareziak	hareziak	PROPN
admet-159	401	20	,	,	PUNCT
admet-159	401	21	m.	m.	NOUN
admet-159	401	22	aschner	aschner	NOUN
admet-159	401	23	,	,	PUNCT
admet-159	401	24	j.b	j.b	PROPN
admet-159	401	25	.	.	PROPN
admet-159	401	26	murdoch	murdoch	PROPN
admet-159	401	27	,	,	PUNCT
admet-159	401	28	w.	w.	PROPN
admet-159	401	29	zheng	zheng	PROPN
admet-159	401	30	,	,	PUNCT
admet-159	401	31	env	env	PROPN
admet-159	401	32	.	.	PUNCT
admet-159	401	33	health	health	NOUN
admet-159	401	34	perspect	perspect	NOUN
admet-159	401	35	.	.	PUNCT
admet-159	402	1	119	119	NUM
admet-159	402	2	(	(	PUNCT
admet-159	402	3	2011	2011	NUM
admet-159	402	4	)	)	PUNCT
admet-159	402	5	219	219	NUM
admet-159	402	6	-	-	SYM
admet-159	402	7	224	224	NUM
admet-159	402	8	.	.	PUNCT
admet-159	403	1	[	[	X
admet-159	403	2	29	29	NUM
admet-159	403	3	]	]	PUNCT
admet-159	403	4	x.	x.	NOUN
admet-159	403	5	fu	fu	PROPN
admet-159	403	6	,	,	PUNCT
admet-159	403	7	y.	y.	PROPN
admet-159	403	8	zhang	zhang	PROPN
admet-159	403	9	,	,	PUNCT
admet-159	403	10	w.	w.	PROPN
admet-159	403	11	jiang	jiang	PROPN
admet-159	403	12	,	,	PUNCT
admet-159	403	13	a.d	a.d	PROPN
admet-159	403	14	.	.	PROPN
admet-159	403	15	monnot	monnot	PROPN
admet-159	403	16	,	,	PUNCT
admet-159	403	17	c.a	c.a	PROPN
admet-159	403	18	.	.	PROPN
admet-159	403	19	bates	bates	PROPN
admet-159	403	20	,	,	PUNCT
admet-159	403	21	w.	w.	PROPN
admet-159	403	22	zheng	zheng	PROPN
admet-159	403	23	,	,	PUNCT
admet-159	403	24	toxicol	toxicol	PROPN
admet-159	403	25	sci	sci	PROPN
admet-159	403	26	139	139	NUM
admet-159	403	27	(	(	PUNCT
admet-159	403	28	2014	2014	NUM
admet-159	403	29	)	)	PUNCT
admet-159	403	30	423	423	NUM
admet-159	403	31	-	-	SYM
admet-159	403	32	451	451	NUM
admet-159	403	33	.	.	PUNCT
admet-159	404	1	[	[	X
admet-159	404	2	30	30	NUM
admet-159	404	3	]	]	PUNCT
admet-159	404	4	z.	z.	PROPN
admet-159	404	5	long	long	PROPN
admet-159	404	6	,	,	PUNCT
admet-159	404	7	y.	y.	PROPN
admet-159	404	8	jiang	jiang	PROPN
admet-159	404	9	,	,	PUNCT
admet-159	404	10	x.	x.	PROPN
admet-159	404	11	li	li	PROPN
admet-159	404	12	,	,	PUNCT
admet-159	404	13	w.	w.	PROPN
admet-159	404	14	fadel	fadel	PROPN
admet-159	404	15	,	,	PUNCT
admet-159	404	16	j.	j.	PROPN
admet-159	404	17	xu	xu	PROPN
admet-159	404	18	,	,	PUNCT
admet-159	404	19	c.	c.	PROPN
admet-159	404	20	yeh	yeh	PROPN
admet-159	404	21	,	,	PUNCT
admet-159	404	22	l.	l.	PROPN
admet-159	404	23	long	long	PROPN
admet-159	404	24	,	,	PUNCT
admet-159	404	25	h.	h.	PROPN
admet-159	404	26	luo	luo	PROPN
admet-159	404	27	,	,	PUNCT
admet-159	404	28	j.	j.	PROPN
admet-159	404	29	harezlak	harezlak	PROPN
admet-159	404	30	,	,	PUNCT
admet-159	404	31	j.b	j.b	PROPN
admet-159	404	32	.	.	PROPN
admet-159	404	33	murdoch	murdoch	PROPN
admet-159	404	34	,	,	PUNCT
admet-159	404	35	w.	w.	PROPN
admet-159	404	36	zheng	zheng	PROPN
admet-159	404	37	,	,	PUNCT
admet-159	404	38	u.	u.	PROPN
admet-159	404	39	dydak	dydak	PROPN
admet-159	404	40	,	,	PUNCT
admet-159	404	41	neurotox	neurotox	NOUN
admet-159	404	42	1669	1669	NUM
admet-159	404	43	(	(	PUNCT
admet-159	404	44	2014	2014	NUM
admet-159	404	45	)	)	PUNCT
admet-159	404	46	1	1	NUM
admet-159	404	47	-	-	SYM
admet-159	404	48	8	8	NUM
admet-159	404	49	.	.	PUNCT
admet-159	405	1	[	[	X
admet-159	405	2	31	31	NUM
admet-159	405	3	]	]	PUNCT
admet-159	405	4	j.	j.	PROPN
admet-159	405	5	crossgrove	crossgrove	PROPN
admet-159	405	6	,	,	PUNCT
admet-159	405	7	w.	w.	PROPN
admet-159	405	8	zheng	zheng	PROPN
admet-159	405	9	,	,	PUNCT
admet-159	405	10	nmr	nmr	NOUN
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admet-159	405	12	17	17	NUM
admet-159	405	13	(	(	PUNCT
admet-159	405	14	2004	2004	NUM
admet-159	405	15	)	)	PUNCT
admet-159	405	16	544	544	NUM
admet-159	405	17	-	-	SYM
admet-159	405	18	553	553	NUM
admet-159	405	19	.	.	PUNCT
admet-159	406	1	[	[	X
admet-159	406	2	32	32	NUM
admet-159	406	3	]	]	SYM
admet-159	406	4	b.a	b.a	PROPN
admet-159	406	5	.	.	PROPN
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admet-159	406	7	.	.	PUNCT
admet-159	407	1	neurotox	neurotox	NOUN
admet-159	407	2	(	(	PUNCT
admet-159	407	3	2013	2013	NUM
admet-159	407	4	)	)	PUNCT
admet-159	408	1	[	[	X
admet-159	408	2	in	in	ADP
admet-159	408	3	press	press	NOUN
admet-159	408	4	]	]	PUNCT
admet-159	408	5	.	.	PUNCT
admet-159	409	1	[	[	X
admet-159	409	2	33	33	NUM
admet-159	409	3	]	]	PUNCT
admet-159	409	4	a.	a.	NOUN
admet-159	409	5	takeda	takeda	PROPN
admet-159	409	6	,	,	PUNCT
admet-159	409	7	t.	t.	PROPN
admet-159	409	8	akiyama	akiyama	PROPN
admet-159	409	9	,	,	PUNCT
admet-159	409	10	j.	j.	PROPN
admet-159	409	11	sawashita	sawashita	PROPN
admet-159	409	12	,	,	PUNCT
admet-159	409	13	s.	s.	PROPN
admet-159	409	14	okada	okada	PROPN
admet-159	409	15	,	,	PUNCT
admet-159	409	16	brain	brain	NOUN
admet-159	409	17	res	re	NOUN
admet-159	409	18	.	.	PUNCT
admet-159	409	19	640	640	NUM
admet-159	409	20	(	(	PUNCT
admet-159	409	21	1994	1994	NUM
admet-159	409	22	)	)	PUNCT
admet-159	409	23	341	341	NUM
admet-159	409	24	-	-	SYM
admet-159	409	25	344	344	NUM
admet-159	409	26	.	.	PUNCT
admet-159	410	1	[	[	X
admet-159	410	2	34	34	NUM
admet-159	410	3	]	]	X
admet-159	410	4	w.	w.	PROPN
admet-159	410	5	zheng	zheng	PROPN
admet-159	410	6	,	,	PUNCT
admet-159	410	7	y.	y.	PROPN
admet-159	410	8	jiang	jiang	PROPN
admet-159	410	9	,	,	PUNCT
admet-159	410	10	y.	y.	PROPN
admet-159	410	11	zhang	zhang	PROPN
admet-159	410	12	,	,	PUNCT
admet-159	410	13	w.	w.	PROPN
admet-159	410	14	jiang	jiang	PROPN
admet-159	410	15	,	,	PUNCT
admet-159	410	16	x.	x.	PROPN
admet-159	410	17	wang	wang	PROPN
admet-159	410	18	,	,	PUNCT
admet-159	410	19	d.m	d.m	PROPN
admet-159	410	20	.	.	PROPN
admet-159	410	21	cowan	cowan	PROPN
admet-159	410	22	,	,	PUNCT
admet-159	410	23	neurotox	neurotox	NOUN
admet-159	410	24	30	30	NUM
admet-159	410	25	(	(	PUNCT
admet-159	410	26	2009	2009	NUM
admet-159	410	27	)	)	PUNCT
admet-159	410	28	240	240	NUM
admet-159	410	29	-	-	SYM
admet-159	410	30	248	248	NUM
admet-159	410	31	.	.	PUNCT
admet-159	411	1	[	[	X
admet-159	411	2	35	35	NUM
admet-159	411	3	]	]	X
admet-159	411	4	r.a	r.a	PROPN
admet-159	411	5	.	.	PROPN
admet-159	411	6	yokel	yokel	PROPN
admet-159	411	7	,	,	PUNCT
admet-159	411	8	j.s	j.s	PROPN
admet-159	411	9	.	.	PROPN
admet-159	411	10	crossgrove	crossgrove	PROPN
admet-159	411	11	,	,	PUNCT
admet-159	411	12	b.l	b.l	PROPN
admet-159	411	13	.	.	PROPN
admet-159	411	14	bukaveckas	bukaveckas	PROPN
admet-159	411	15	,	,	PUNCT
admet-159	411	16	neurotox	neurotox	NOUN
admet-159	411	17	24	24	NUM
admet-159	411	18	(	(	PUNCT
admet-159	411	19	2003	2003	NUM
admet-159	411	20	)	)	PUNCT
admet-159	411	21	15	15	NUM
admet-159	411	22	-	-	SYM
admet-159	411	23	22	22	NUM
admet-159	411	24	.	.	PUNCT
admet-159	412	1	[	[	X
admet-159	412	2	36	36	NUM
admet-159	412	3	]	]	X
admet-159	412	4	c.	c.	PROPN
admet-159	412	5	schmitt	schmitt	PROPN
admet-159	412	6	,	,	PUNCT
admet-159	412	7	n.	n.	PROPN
admet-159	412	8	strazielle	strazielle	PROPN
admet-159	412	9	,	,	PUNCT
admet-159	412	10	p.	p.	PROPN
admet-159	412	11	richaud	richaud	PROPN
admet-159	412	12	,	,	PUNCT
admet-159	412	13	a.	a.	NOUN
admet-159	412	14	boubon	boubon	PROPN
admet-159	412	15	,	,	PUNCT
admet-159	412	16	j.f	j.f	PROPN
admet-159	412	17	.	.	PROPN
admet-159	412	18	ghersi	ghersi	NOUN
admet-159	412	19	-	-	PUNCT
admet-159	412	20	egea	egea	NOUN
admet-159	412	21	,	,	PUNCT
admet-159	412	22	j.	j.	PROPN
admet-159	412	23	neurochem	neurochem	PROPN
admet-159	412	24	.	.	PUNCT
admet-159	413	1	117	117	NUM
admet-159	413	2	(	(	PUNCT
admet-159	413	3	2011	2011	NUM
admet-159	413	4	)	)	PUNCT
admet-159	413	5	747	747	NUM
admet-159	413	6	-	-	SYM
admet-159	413	7	756	756	NUM
admet-159	413	8	.	.	PUNCT
admet-159	414	1	[	[	X
admet-159	414	2	37	37	NUM
admet-159	414	3	]	]	PUNCT
admet-159	414	4	a.	a.	NOUN
admet-159	414	5	takeda	takeda	PROPN
admet-159	414	6	,	,	PUNCT
admet-159	414	7	j.	j.	PROPN
admet-159	414	8	sawashita	sawashita	PROPN
admet-159	414	9	,	,	PUNCT
admet-159	414	10	s.	s.	PROPN
admet-159	414	11	okada	okada	PROPN
admet-159	414	12	,	,	PUNCT
admet-159	414	13	brain	brain	NOUN
admet-159	414	14	res	re	NOUN
admet-159	414	15	.	.	PUNCT
admet-159	414	16	695	695	NUM
admet-159	414	17	(	(	PUNCT
admet-159	414	18	1995	1995	NUM
admet-159	414	19	)	)	PUNCT
admet-159	414	20	53	53	NUM
admet-159	414	21	-	-	SYM
admet-159	414	22	58	58	NUM
admet-159	414	23	.	.	PUNCT
admet-159	415	1	[	[	X
admet-159	415	2	38	38	NUM
admet-159	415	3	]	]	X
admet-159	415	4	v.n	v.n	PROPN
admet-159	415	5	.	.	PROPN
admet-159	415	6	uversky	uversky	PROPN
admet-159	415	7	,	,	PUNCT
admet-159	415	8	j.	j.	PROPN
admet-159	415	9	li	li	PROPN
admet-159	415	10	,	,	PUNCT
admet-159	415	11	a.l	a.l	PROPN
admet-159	415	12	.	.	PROPN
admet-159	415	13	fink	fink	PROPN
admet-159	415	14	,	,	PUNCT
admet-159	415	15	febs	febs	NOUN
admet-159	415	16	letters	letter	NOUN
admet-159	415	17	500	500	NUM
admet-159	415	18	(	(	PUNCT
admet-159	415	19	2001	2001	NUM
admet-159	415	20	)	)	PUNCT
admet-159	415	21	105	105	NUM
admet-159	415	22	-	-	SYM
admet-159	415	23	108	108	NUM
admet-159	415	24	.	.	PUNCT
admet-159	416	1	[	[	X
admet-159	416	2	39	39	NUM
admet-159	416	3	]	]	PUNCT
admet-159	416	4	a.	a.	NOUN
admet-159	416	5	binolfi	binolfi	NOUN
admet-159	416	6	,	,	PUNCT
admet-159	416	7	r.m	r.m	PROPN
admet-159	416	8	.	.	PROPN
admet-159	416	9	rasia	rasia	PROPN
admet-159	416	10	,	,	PUNCT
admet-159	416	11	c.w	c.w	PROPN
admet-159	416	12	.	.	PROPN
admet-159	416	13	bertoncini	bertoncini	PROPN
admet-159	416	14	,	,	PUNCT
admet-159	416	15	m.	m.	NOUN
admet-159	416	16	ceolin	ceolin	PROPN
admet-159	416	17	,	,	PUNCT
admet-159	416	18	c.	c.	PROPN
admet-159	416	19	zweckstetter	zweckstetter	PROPN
admet-159	416	20	griesinger	griesinger	PROPN
admet-159	416	21	,	,	PUNCT
admet-159	416	22	t.m	t.m	PROPN
admet-159	416	23	.	.	PROPN
admet-159	416	24	jovin	jovin	PROPN
admet-159	416	25	,	,	PUNCT
admet-159	416	26	c.o	c.o	PROPN
admet-159	416	27	.	.	PROPN
admet-159	416	28	fernândez	fernândez	PROPN
admet-159	416	29	,	,	PUNCT
admet-159	416	30	j.	j.	PROPN
admet-159	416	31	am	am	PROPN
admet-159	416	32	.	.	PUNCT
admet-159	417	1	chem	chem	NOUN
admet-159	417	2	.	.	PUNCT
admet-159	418	1	soc	soc	PROPN
admet-159	418	2	.	.	PUNCT
admet-159	419	1	128	128	NUM
admet-159	419	2	(	(	PUNCT
admet-159	419	3	2006	2006	NUM
admet-159	419	4	)	)	PUNCT
admet-159	419	5	9893	9893	NUM
admet-159	419	6	-	-	SYM
admet-159	419	7	9901	9901	NUM
admet-159	419	8	.	.	PUNCT
admet-159	420	1	[	[	X
admet-159	420	2	40	40	NUM
admet-159	420	3	]	]	PUNCT
admet-159	420	4	t.	t.	PROPN
admet-159	420	5	cai	cai	PROPN
admet-159	420	6	,	,	PUNCT
admet-159	420	7	t.	t.	PROPN
admet-159	420	8	yao	yao	PROPN
admet-159	420	9	,	,	PUNCT
admet-159	420	10	g.	g.	PROPN
admet-159	420	11	zheng	zheng	PROPN
admet-159	420	12	,	,	PUNCT
admet-159	420	13	y.	y.	PROPN
admet-159	420	14	chen	chen	PROPN
admet-159	420	15	,	,	PUNCT
admet-159	420	16	k.	k.	PROPN
admet-159	420	17	du	du	PROPN
admet-159	420	18	,	,	PUNCT
admet-159	420	19	y.	y.	PROPN
admet-159	420	20	cao	cao	PROPN
admet-159	420	21	,	,	PUNCT
admet-159	420	22	x.	x.	PROPN
admet-159	420	23	shen	shen	PROPN
admet-159	420	24	,	,	PUNCT
admet-159	420	25	j.	j.	PROPN
admet-159	420	26	chen	chen	PROPN
admet-159	420	27	,	,	PUNCT
admet-159	420	28	w.	w.	PROPN
admet-159	420	29	luo	luo	PROPN
admet-159	420	30	,	,	PUNCT
admet-159	420	31	brain	brain	NOUN
admet-159	420	32	res	re	NOUN
admet-159	420	33	.	.	PUNCT
admet-159	420	34	1359	1359	NUM
admet-159	420	35	(	(	PUNCT
admet-159	420	36	2010	2010	NUM
admet-159	420	37	)	)	PUNCT
admet-159	420	38	201207	201207	NUM
admet-159	420	39	.	.	PUNCT
admet-159	421	1	[	[	X
admet-159	421	2	41	41	NUM
admet-159	421	3	]	]	X
admet-159	421	4	y.	y.	PROPN
admet-159	421	5	li	li	PROPN
admet-159	421	6	,	,	PUNCT
admet-159	421	7	l.	l.	PROPN
admet-159	421	8	sun	sun	PROPN
admet-159	421	9	,	,	PUNCT
admet-159	421	10	t.	t.	PROPN
admet-159	421	11	cai	cai	PROPN
admet-159	421	12	,	,	PUNCT
admet-159	421	13	y.	y.	PROPN
admet-159	421	14	zhang	zhang	PROPN
admet-159	421	15	,	,	PUNCT
admet-159	421	16	s.	s.	PROPN
admet-159	421	17	lv	lv	PROPN
admet-159	421	18	,	,	PUNCT
admet-159	421	19	y.	y.	PROPN
admet-159	421	20	wang	wang	PROPN
admet-159	421	21	,	,	PUNCT
admet-159	421	22	l.	l.	PROPN
admet-159	421	23	ye	ye	PROPN
admet-159	421	24	,	,	PUNCT
admet-159	421	25	brain	brain	NOUN
admet-159	421	26	res	re	NOUN
admet-159	421	27	.	.	PUNCT
admet-159	422	1	bull	bull	NOUN
admet-159	422	2	.	.	PUNCT
admet-159	423	1	81	81	NUM
admet-159	423	2	(	(	PUNCT
admet-159	423	3	2010	2010	NUM
admet-159	423	4	)	)	PUNCT
admet-159	423	5	428	428	NUM
admet-159	423	6	-	-	SYM
admet-159	423	7	433	433	NUM
admet-159	423	8	.	.	PUNCT
admet-159	424	1	[	[	X
admet-159	424	2	42	42	NUM
admet-159	424	3	]	]	PUNCT
admet-159	424	4	w.	w.	PROPN
admet-159	424	5	zheng	zheng	PROPN
admet-159	424	6	,	,	PUNCT
admet-159	424	7	q.	q.	PROPN
admet-159	424	8	zhao	zhao	PROPN
admet-159	424	9	,	,	PUNCT
admet-159	424	10	methods	method	NOUN
admet-159	424	11	mol	mol	PROPN
admet-159	424	12	.	.	PUNCT
admet-159	425	1	biol	biol	PROPN
admet-159	425	2	.	.	PUNCT
admet-159	426	1	188	188	NUM
admet-159	426	2	(	(	PUNCT
admet-159	426	3	2002	2002	NUM
admet-159	426	4	)	)	PUNCT
admet-159	426	5	99	99	NUM
admet-159	426	6	-	-	SYM
admet-159	426	7	114	114	NUM
admet-159	426	8	.	.	PUNCT
admet-159	427	1	admet	admet	PROPN
admet-159	427	2	&	&	CCONJ
admet-159	427	3	dmpk	dmpk	PROPN
admet-159	427	4	3(1	3(1	NUM
admet-159	427	5	)	)	PUNCT
admet-159	427	6	(	(	PUNCT
admet-159	427	7	2015	2015	NUM
admet-159	427	8	)	)	PUNCT
admet-159	427	9	15	15	NUM
admet-159	427	10	-	-	SYM
admet-159	427	11	33	33	NUM
admet-159	427	12	effects	effect	NOUN
admet-159	427	13	of	of	ADP
admet-159	427	14	manganese	manganese	ADJ
admet-159	427	15	exposure	exposure	NOUN
admet-159	427	16	on	on	ADP
admet-159	427	17	expression	expression	NOUN
admet-159	427	18	and	and	CCONJ
admet-159	427	19	transport	transport	NOUN
admet-159	427	20	of	of	ADP
admet-159	427	21	-synuclein	-synuclein	PROPN
admet-159	427	22	doi	doi	NOUN
admet-159	427	23	:	:	PUNCT
admet-159	427	24	10.5599	10.5599	NUM
admet-159	427	25	/	/	SYM
admet-159	427	26	admet.3.1.159	admet.3.1.159	NUM
admet-159	427	27	31	31	NUM
admet-159	427	28	[	[	X
admet-159	427	29	43	43	NUM
admet-159	427	30	]	]	X
admet-159	427	31	g.j	g.j	PROPN
admet-159	427	32	.	.	PROPN
admet-159	427	33	li	li	PROPN
admet-159	427	34	,	,	PUNCT
admet-159	427	35	q.	q.	PROPN
admet-159	427	36	zhao	zhao	PROPN
admet-159	427	37	,	,	PUNCT
admet-159	427	38	w.	w.	PROPN
admet-159	427	39	zheng	zheng	PROPN
admet-159	427	40	,	,	PUNCT
admet-159	427	41	toxicol	toxicol	PROPN
admet-159	427	42	.	.	PUNCT
admet-159	427	43	appl	appl	PROPN
admet-159	427	44	.	.	PUNCT
admet-159	428	1	pharmacol	pharmacol	PROPN
admet-159	428	2	.	.	PUNCT
admet-159	429	1	205	205	NUM
admet-159	429	2	(	(	PUNCT
admet-159	429	3	2005	2005	NUM
admet-159	429	4	)	)	PUNCT
admet-159	429	5	188	188	NUM
admet-159	429	6	-	-	SYM
admet-159	429	7	200	200	NUM
admet-159	429	8	.	.	PUNCT
admet-159	430	1	[	[	X
admet-159	430	2	44	44	NUM
admet-159	430	3	]	]	PUNCT
admet-159	430	4	x.	x.	PROPN
admet-159	430	5	wang	wang	PROPN
admet-159	430	6	,	,	PUNCT
admet-159	430	7	g.j	g.j	PROPN
admet-159	430	8	.	.	PROPN
admet-159	430	9	li	li	PROPN
admet-159	430	10	,	,	PUNCT
admet-159	430	11	w.	w.	PROPN
admet-159	430	12	zheng	zheng	PROPN
admet-159	430	13	,	,	PUNCT
admet-159	430	14	brain	brain	NOUN
admet-159	430	15	res	re	NOUN
admet-159	430	16	.	.	PROPN
admet-159	430	17	1097	1097	NUM
admet-159	430	18	(	(	PUNCT
admet-159	430	19	2006	2006	NUM
admet-159	430	20	)	)	PUNCT
admet-159	430	21	1	1	NUM
admet-159	430	22	-	-	SYM
admet-159	430	23	10	10	NUM
admet-159	430	24	.	.	PUNCT
admet-159	431	1	[	[	X
admet-159	431	2	45	45	NUM
admet-159	431	3	]	]	PUNCT
admet-159	431	4	w.	w.	PROPN
admet-159	431	5	zheng	zheng	PROPN
admet-159	431	6	,	,	PUNCT
admet-159	431	7	q.	q.	PROPN
admet-159	431	8	zhao	zhao	PROPN
admet-159	431	9	,	,	PUNCT
admet-159	431	10	j.h	j.h	PROPN
admet-159	431	11	.	.	PROPN
admet-159	431	12	graziano	graziano	PROPN
admet-159	431	13	,	,	PUNCT
admet-159	431	14	in	in	ADP
admet-159	431	15	vitro	vitro	X
admet-159	431	16	cell	cell	PROPN
admet-159	431	17	dev	dev	PROPN
admet-159	431	18	.	.	PUNCT
admet-159	432	1	biol	biol	PROPN
admet-159	432	2	.	.	PUNCT
admet-159	433	1	34	34	NUM
admet-159	433	2	(	(	PUNCT
admet-159	433	3	1998	1998	NUM
admet-159	433	4	)	)	PUNCT
admet-159	433	5	40	40	NUM
admet-159	433	6	-	-	SYM
admet-159	433	7	45	45	NUM
admet-159	433	8	.	.	PUNCT
admet-159	434	1	[	[	X
admet-159	434	2	46	46	NUM
admet-159	434	3	]	]	X
admet-159	434	4	l.z	l.z	PROPN
admet-159	434	5	.	.	PROPN
admet-159	434	6	shi	shi	PROPN
admet-159	434	7	,	,	PUNCT
admet-159	434	8	w.	w.	PROPN
admet-159	434	9	zheng	zheng	PROPN
admet-159	434	10	,	,	PUNCT
admet-159	434	11	brain	brain	NOUN
admet-159	434	12	res	re	NOUN
admet-159	434	13	.	.	PROPN
admet-159	434	14	1057	1057	NUM
admet-159	434	15	(	(	PUNCT
admet-159	434	16	2005	2005	NUM
admet-159	434	17	)	)	PUNCT
admet-159	434	18	37	37	NUM
admet-159	434	19	-	-	SYM
admet-159	434	20	48	48	NUM
admet-159	434	21	.	.	PUNCT
admet-159	435	1	[	[	X
admet-159	435	2	47	47	NUM
admet-159	435	3	]	]	X
admet-159	435	4	a.d	a.d	PROPN
admet-159	435	5	.	.	PROPN
admet-159	435	6	monnot	monnot	PROPN
admet-159	435	7	,	,	PUNCT
admet-159	435	8	m.	m.	NOUN
admet-159	435	9	behl	behl	PROPN
admet-159	435	10	,	,	PUNCT
admet-159	435	11	s.	s.	PROPN
admet-159	435	12	ho	ho	PROPN
admet-159	435	13	,	,	PUNCT
admet-159	435	14	w.	w.	PROPN
admet-159	435	15	zheng	zheng	PROPN
admet-159	435	16	,	,	PUNCT
admet-159	435	17	toxicol	toxicol	PROPN
admet-159	435	18	.	.	PUNCT
admet-159	436	1	appl	appl	PROPN
admet-159	436	2	.	.	PUNCT
admet-159	437	1	pharmacol	pharmacol	PROPN
admet-159	437	2	.	.	PUNCT
admet-159	438	1	256	256	NUM
admet-159	438	2	(	(	PUNCT
admet-159	438	3	2011	2011	NUM
admet-159	438	4	)	)	PUNCT
admet-159	438	5	249	249	NUM
admet-159	438	6	-	-	SYM
admet-159	438	7	257	257	NUM
admet-159	438	8	.	.	PUNCT
admet-159	439	1	[	[	X
admet-159	439	2	48	48	NUM
admet-159	439	3	]	]	PUNCT
admet-159	439	4	g.	g.	PROPN
admet-159	439	5	zheng	zheng	PROPN
admet-159	439	6	,	,	PUNCT
admet-159	439	7	j.	j.	PROPN
admet-159	439	8	chen	chen	PROPN
admet-159	439	9	,	,	PUNCT
admet-159	439	10	w.	w.	PROPN
admet-159	439	11	zheng	zheng	PROPN
admet-159	439	12	,	,	PUNCT
admet-159	439	13	toxicol	toxicol	PROPN
admet-159	439	14	.	.	PUNCT
admet-159	440	1	appl	appl	PROPN
admet-159	440	2	.	.	PUNCT
admet-159	441	1	pharamcol	pharamcol	PROPN
admet-159	441	2	.	.	PROPN
admet-159	442	1	260	260	NUM
admet-159	442	2	(	(	PUNCT
admet-159	442	3	2012	2012	NUM
admet-159	442	4	)	)	PUNCT
admet-159	442	5	285	285	NUM
admet-159	442	6	-	-	SYM
admet-159	442	7	293	293	NUM
admet-159	442	8	.	.	PUNCT
admet-159	443	1	[	[	X
admet-159	443	2	49	49	NUM
admet-159	443	3	]	]	PUNCT
admet-159	443	4	h.	h.	PROPN
admet-159	443	5	zhang	zhang	PROPN
admet-159	443	6	,	,	PUNCT
admet-159	443	7	a.	a.	PROPN
admet-159	443	8	griggs	griggs	PROPN
admet-159	443	9	,	,	PUNCT
admet-159	443	10	j.c	j.c	PROPN
admet-159	443	11	.	.	PROPN
admet-159	443	12	rochet	rochet	PROPN
admet-159	443	13	,	,	PUNCT
admet-159	443	14	l.a	l.a	PROPN
admet-159	443	15	.	.	PROPN
admet-159	443	16	stanciu	stanciu	PROPN
admet-159	443	17	,	,	PUNCT
admet-159	443	18	biophys	biophy	NOUN
admet-159	443	19	.	.	PUNCT
admet-159	444	1	j.	j.	PROPN
admet-159	444	2	104	104	PROPN
admet-159	444	3	(	(	PUNCT
admet-159	444	4	2013	2013	NUM
admet-159	444	5	)	)	PUNCT
admet-159	444	6	2706	2706	NUM
admet-159	444	7	-	-	SYM
admet-159	444	8	2713	2713	NUM
admet-159	444	9	.	.	PUNCT
admet-159	445	1	[	[	X
admet-159	445	2	50	50	NUM
admet-159	445	3	]	]	X
admet-159	445	4	h.	h.	PROPN
admet-159	445	5	lee	lee	PROPN
admet-159	445	6	,	,	PUNCT
admet-159	445	7	f.	f.	PROPN
admet-159	445	8	khoshaghideh	khoshaghideh	PROPN
admet-159	445	9	,	,	PUNCT
admet-159	445	10	s.	s.	PROPN
admet-159	445	11	patel	patel	PROPN
admet-159	445	12	,	,	PUNCT
admet-159	445	13	s.	s.	PROPN
admet-159	445	14	lee	lee	PROPN
admet-159	445	15	,	,	PUNCT
admet-159	445	16	j.	j.	PROPN
admet-159	445	17	neurosci	neurosci	PROPN
admet-159	445	18	.	.	PUNCT
admet-159	446	1	24	24	NUM
admet-159	446	2	(	(	PUNCT
admet-159	446	3	2004	2004	NUM
admet-159	446	4	)	)	PUNCT
admet-159	446	5	1888	1888	NUM
admet-159	446	6	-	-	SYM
admet-159	446	7	1896	1896	NUM
admet-159	446	8	.	.	PUNCT
admet-159	447	1	[	[	X
admet-159	447	2	51	51	NUM
admet-159	447	3	]	]	X
admet-159	447	4	y.	y.	PROPN
admet-159	447	5	lu	lu	PROPN
admet-159	447	6	,	,	PUNCT
admet-159	447	7	m.	m.	NOUN
admet-159	447	8	prudent	prudent	PROPN
admet-159	447	9	,	,	PUNCT
admet-159	447	10	b.	b.	PROPN
admet-159	447	11	fauvet	fauvet	PROPN
admet-159	447	12	,	,	PUNCT
admet-159	447	13	h.a	h.a	PROPN
admet-159	447	14	.	.	PROPN
admet-159	447	15	lashuel	lashuel	PROPN
admet-159	447	16	,	,	PUNCT
admet-159	447	17	h.h	h.h	PROPN
admet-159	447	18	.	.	PROPN
admet-159	447	19	girault	girault	NOUN
admet-159	447	20	,	,	PUNCT
admet-159	447	21	acs	acs	PROPN
admet-159	447	22	chem	chem	NOUN
admet-159	447	23	.	.	PUNCT
admet-159	447	24	neurosci	neurosci	PROPN
admet-159	447	25	.	.	PUNCT
admet-159	448	1	2	2	NUM
admet-159	448	2	(	(	PUNCT
admet-159	448	3	2011	2011	NUM
admet-159	448	4	)	)	PUNCT
admet-159	448	5	667	667	NUM
admet-159	448	6	-	-	SYM
admet-159	448	7	675	675	NUM
admet-159	448	8	.	.	PUNCT
admet-159	449	1	[	[	X
admet-159	449	2	52	52	NUM
admet-159	449	3	]	]	PUNCT
admet-159	449	4	t.	t.	PROPN
admet-159	449	5	bartels	bartels	PROPN
admet-159	449	6	,	,	PUNCT
admet-159	449	7	j.g	j.g	PROPN
admet-159	449	8	.	.	PROPN
admet-159	449	9	choi	choi	PROPN
admet-159	449	10	,	,	PUNCT
admet-159	449	11	d.j	d.j	PROPN
admet-159	449	12	.	.	PROPN
admet-159	449	13	selkoe	selkoe	PROPN
admet-159	449	14	,	,	PUNCT
admet-159	449	15	nature	nature	NOUN
admet-159	449	16	477	477	NUM
admet-159	449	17	(	(	PUNCT
admet-159	449	18	2011	2011	NUM
admet-159	449	19	)	)	PUNCT
admet-159	449	20	107	107	NUM
admet-159	449	21	-	-	SYM
admet-159	449	22	111	111	NUM
admet-159	449	23	.	.	PUNCT
admet-159	450	1	[	[	X
admet-159	450	2	53	53	NUM
admet-159	450	3	]	]	PUNCT
admet-159	450	4	b.	b.	PROPN
admet-159	450	5	fauvet	fauvet	PROPN
admet-159	450	6	,	,	PUNCT
admet-159	450	7	m.m	m.m	PROPN
admet-159	450	8	.	.	PROPN
admet-159	450	9	kamdem	kamdem	PROPN
admet-159	450	10	,	,	PUNCT
admet-159	450	11	m.b	m.b	PROPN
admet-159	450	12	.	.	PROPN
admet-159	450	13	fares	fare	NOUN
admet-159	450	14	,	,	PUNCT
admet-159	450	15	c.	c.	PROPN
admet-159	450	16	desobry	desobry	PROPN
admet-159	450	17	,	,	PUNCT
admet-159	450	18	s.	s.	PROPN
admet-159	450	19	michael	michael	PROPN
admet-159	450	20	,	,	PUNCT
admet-159	450	21	m.t	m.t	PROPN
admet-159	450	22	.	.	PROPN
admet-159	450	23	ardah	ardah	PROPN
admet-159	450	24	,	,	PUNCT
admet-159	450	25	e.	e.	PROPN
admet-159	450	26	tsika	tsika	PROPN
admet-159	450	27	,	,	PUNCT
admet-159	450	28	p.	p.	NOUN
admet-159	450	29	coune	coune	NOUN
admet-159	450	30	,	,	PUNCT
admet-159	450	31	m.	m.	NOUN
admet-159	450	32	prudent	prudent	NOUN
admet-159	450	33	,	,	PUNCT
admet-159	450	34	n.	n.	NOUN
admet-159	450	35	lion	lion	NOUN
admet-159	450	36	,	,	PUNCT
admet-159	450	37	d.	d.	PROPN
admet-159	450	38	eliezer	eliezer	PROPN
admet-159	450	39	,	,	PUNCT
admet-159	450	40	d.j	d.j	PROPN
admet-159	450	41	.	.	PROPN
admet-159	450	42	moore	moore	PROPN
admet-159	450	43	,	,	PUNCT
admet-159	450	44	b.	b.	PROPN
admet-159	450	45	schneider	schneider	PROPN
admet-159	450	46	,	,	PUNCT
admet-159	450	47	p.	p.	PROPN
admet-159	450	48	aebischer	aebischer	NOUN
admet-159	450	49	,	,	PUNCT
admet-159	450	50	o.m	o.m	PROPN
admet-159	450	51	.	.	PUNCT
admet-159	450	52	el	el	PROPN
admet-159	450	53	-	-	NOUN
admet-159	450	54	agnaf	agnaf	PROPN
admet-159	450	55	,	,	PUNCT
admet-159	450	56	e.	e.	PROPN
admet-159	450	57	masliah	masliah	PROPN
admet-159	450	58	,	,	PUNCT
admet-159	450	59	h.a	h.a	PROPN
admet-159	450	60	.	.	PROPN
admet-159	450	61	lashuel	lashuel	PROPN
admet-159	450	62	,	,	PUNCT
admet-159	450	63	j.	j.	PROPN
admet-159	450	64	biol	biol	PROPN
admet-159	450	65	.	.	PUNCT
admet-159	450	66	chem	chem	PROPN
admet-159	450	67	.	.	PUNCT
admet-159	451	1	(	(	PUNCT
admet-159	451	2	2012	2012	NUM
admet-159	451	3	)	)	PUNCT
admet-159	451	4	1	1	NUM
admet-159	451	5	-	-	SYM
admet-159	451	6	35	35	NUM
admet-159	451	7	.	.	PUNCT
admet-159	452	1	[	[	X
admet-159	452	2	54	54	NUM
admet-159	452	3	]	]	X
admet-159	452	4	d.	d.	PROPN
admet-159	452	5	kuzdas	kuzdas	PROPN
admet-159	452	6	-	-	PUNCT
admet-159	452	7	wood	wood	NOUN
admet-159	452	8	,	,	PUNCT
admet-159	452	9	n.	n.	NOUN
admet-159	452	10	stefanova	stefanova	PROPN
admet-159	452	11	,	,	PUNCT
admet-159	452	12	k.a	k.a	PROPN
admet-159	452	13	.	.	PUNCT
admet-159	452	14	jellinger	jellinger	PROPN
admet-159	452	15	,	,	PUNCT
admet-159	452	16	k.	k.	PROPN
admet-159	452	17	seppi	seppi	PROPN
admet-159	452	18	,	,	PUNCT
admet-159	452	19	m.g	m.g	PROPN
admet-159	452	20	.	.	PROPN
admet-159	452	21	schlossmacher	schlossmacher	PROPN
admet-159	452	22	,	,	PUNCT
admet-159	452	23	w.	w.	PROPN
admet-159	452	24	poewe	poewe	PROPN
admet-159	452	25	,	,	PUNCT
admet-159	452	26	g.k	g.k	PROPN
admet-159	452	27	.	.	PROPN
admet-159	452	28	wenning	wenning	NOUN
admet-159	452	29	,	,	PUNCT
admet-159	452	30	prog	prog	NOUN
admet-159	452	31	.	.	PUNCT
admet-159	452	32	neurobiol	neurobiol	PROPN
admet-159	452	33	.	.	PUNCT
admet-159	453	1	118	118	NUM
admet-159	453	2	(	(	PUNCT
admet-159	453	3	2014	2014	NUM
admet-159	453	4	)	)	PUNCT
admet-159	453	5	19	19	NUM
admet-159	453	6	-	-	SYM
admet-159	453	7	35	35	NUM
admet-159	453	8	[	[	X
admet-159	453	9	55	55	NUM
admet-159	453	10	]	]	PUNCT
admet-159	453	11	a.	a.	NOUN
admet-159	453	12	binolfi	binolfi	PROPN
admet-159	453	13	,	,	PUNCT
admet-159	453	14	a.a	a.a	PROPN
admet-159	453	15	.	.	PROPN
admet-159	453	16	valiente	valiente	PROPN
admet-159	453	17	-	-	PUNCT
admet-159	453	18	gabioud	gabioud	PROPN
admet-159	453	19	,	,	PUNCT
admet-159	453	20	r.	r.	PROPN
admet-159	453	21	duran	duran	PROPN
admet-159	453	22	,	,	PUNCT
admet-159	453	23	m.	m.	NOUN
admet-159	453	24	zweckstetter	zweckstetter	PROPN
admet-159	453	25	,	,	PUNCT
admet-159	453	26	c.	c.	PROPN
admet-159	453	27	griesinger	griesinger	PROPN
admet-159	453	28	,	,	PUNCT
admet-159	453	29	c.o	c.o	PROPN
admet-159	453	30	.	.	PROPN
admet-159	453	31	fernandez	fernandez	PROPN
admet-159	453	32	,	,	PUNCT
admet-159	453	33	j.	j.	PROPN
admet-159	453	34	am	am	PROPN
admet-159	453	35	.	.	PUNCT
admet-159	454	1	chem	chem	NOUN
admet-159	454	2	.	.	PUNCT
admet-159	455	1	soc	soc	PROPN
admet-159	455	2	.	.	PUNCT
admet-159	456	1	133	133	NUM
admet-159	456	2	(	(	PUNCT
admet-159	456	3	2011	2011	NUM
admet-159	456	4	)	)	PUNCT
admet-159	456	5	194	194	NUM
admet-159	456	6	-	-	SYM
admet-159	456	7	196	196	NUM
admet-159	456	8	.	.	PUNCT
admet-159	457	1	[	[	X
admet-159	457	2	56	56	NUM
admet-159	457	3	]	]	X
admet-159	457	4	t.r	t.r	PROPN
admet-159	457	5	.	.	PROPN
admet-159	457	6	guilarte	guilarte	NOUN
admet-159	457	7	,	,	PUNCT
admet-159	457	8	frontiers	frontier	NOUN
admet-159	457	9	in	in	ADP
admet-159	457	10	aging	age	VERB
admet-159	457	11	neuroscience	neuroscience	NOUN
admet-159	457	12	5	5	NUM
admet-159	457	13	(	(	PUNCT
admet-159	457	14	2013	2013	NUM
admet-159	457	15	)	)	PUNCT
admet-159	457	16	1	1	NUM
admet-159	457	17	-	-	SYM
admet-159	457	18	10	10	NUM
admet-159	457	19	.	.	PUNCT
admet-159	458	1	[	[	X
admet-159	458	2	57	57	NUM
admet-159	458	3	]	]	PUNCT
admet-159	458	4	a.	a.	NOUN
admet-159	458	5	ahmad	ahmad	PROPN
admet-159	458	6	,	,	PUNCT
admet-159	458	7	c.s	c.s	PROPN
admet-159	458	8	.	.	PROPN
admet-159	458	9	burns	burn	NOUN
admet-159	458	10	,	,	PUNCT
admet-159	458	11	a.l	a.l	PROPN
admet-159	458	12	.	.	PROPN
admet-159	458	13	fink	fink	PROPN
admet-159	458	14	,	,	PUNCT
admet-159	458	15	v.n	v.n	PROPN
admet-159	458	16	.	.	PROPN
admet-159	458	17	uversky	uversky	PROPN
admet-159	458	18	,	,	PUNCT
admet-159	458	19	j.biomol	j.biomol	PRON
admet-159	458	20	.	.	PUNCT
admet-159	459	1	struc.dyn	struc.dyn	X
admet-159	459	2	.	.	PROPN
admet-159	459	3	29	29	NUM
admet-159	459	4	(	(	PUNCT
admet-159	459	5	2013	2013	NUM
admet-159	459	6	)	)	PUNCT
admet-159	459	7	825	825	NUM
admet-159	459	8	-	-	SYM
admet-159	459	9	842	842	NUM
admet-159	459	10	.	.	PUNCT
admet-159	460	1	[	[	X
admet-159	460	2	58	58	NUM
admet-159	460	3	]	]	X
admet-159	460	4	f.	f.	PROPN
admet-159	460	5	camponeschi	camponeschi	PROPN
admet-159	460	6	,	,	PUNCT
admet-159	460	7	d.	d.	PROPN
admet-159	460	8	valensin	valensin	PROPN
admet-159	460	9	,	,	PUNCT
admet-159	460	10	i.	i.	PROPN
admet-159	460	11	tessari	tessari	PROPN
admet-159	460	12	,	,	PUNCT
admet-159	460	13	l.	l.	PROPN
admet-159	460	14	bubacco	bubacco	PROPN
admet-159	460	15	,	,	PUNCT
admet-159	460	16	s.	s.	PROPN
admet-159	460	17	dell’acqua	dell’acqua	PROPN
admet-159	460	18	,	,	PUNCT
admet-159	460	19	l.	l.	PROPN
admet-159	460	20	casella	casella	PROPN
admet-159	460	21	,	,	PUNCT
admet-159	460	22	e.	e.	PROPN
admet-159	460	23	monzani	monzani	PROPN
admet-159	460	24	,	,	PUNCT
admet-159	460	25	e.	e.	PROPN
admet-159	460	26	gaggelli	gaggelli	PROPN
admet-159	460	27	,	,	PUNCT
admet-159	460	28	g.	g.	PROPN
admet-159	460	29	valensin	valensin	PROPN
admet-159	460	30	,	,	PUNCT
admet-159	460	31	inorg	inorg	PROPN
admet-159	460	32	.	.	PUNCT
admet-159	461	1	chem	chem	PROPN
admet-159	461	2	.	.	PUNCT
admet-159	462	1	52	52	NUM
admet-159	462	2	(	(	PUNCT
admet-159	462	3	2013	2013	NUM
admet-159	462	4	)	)	PUNCT
admet-159	462	5	1358	1358	NUM
admet-159	462	6	-	-	SYM
admet-159	462	7	1367	1367	NUM
admet-159	462	8	.	.	PUNCT
admet-159	463	1	bates	bates	PROPN
admet-159	463	2	et	et	PROPN
admet-159	463	3	al	al	PROPN
admet-159	463	4	.	.	PROPN
admet-159	463	5	admet	admet	PROPN
admet-159	463	6	&	&	CCONJ
admet-159	463	7	dmpk	dmpk	PROPN
admet-159	463	8	3(1	3(1	NUM
admet-159	463	9	)	)	PUNCT
admet-159	463	10	(	(	PUNCT
admet-159	463	11	2015	2015	NUM
admet-159	463	12	)	)	PUNCT
admet-159	463	13	15	15	NUM
admet-159	463	14	-	-	SYM
admet-159	463	15	33	33	NUM
admet-159	463	16	32	32	NUM
admet-159	463	17	supplemental	supplemental	ADJ
admet-159	463	18	fugures	fugure	NOUN
admet-159	463	19	figure	figure	NOUN
admet-159	463	20	s1	s1	PROPN
admet-159	463	21	.	.	PUNCT
admet-159	464	1	diagram	diagram	NOUN
admet-159	464	2	of	of	ADP
admet-159	464	3	two	two	NUM
admet-159	464	4	-	-	PUNCT
admet-159	464	5	chamber	chamber	NOUN
admet-159	464	6	transwell	transwell	NOUN
admet-159	464	7	transport	transport	NOUN
admet-159	464	8	system	system	NOUN
admet-159	464	9	.	.	PUNCT
admet-159	465	1	the	the	DET
admet-159	465	2	primary	primary	ADJ
admet-159	465	3	choroidal	choroidal	ADJ
admet-159	465	4	epithelial	epithelial	ADJ
admet-159	465	5	cells	cell	NOUN
admet-159	465	6	are	be	AUX
admet-159	465	7	cultured	cultured	ADJ
admet-159	465	8	on	on	ADP
admet-159	465	9	a	a	DET
admet-159	465	10	porous	porous	ADJ
admet-159	465	11	member	member	NOUN
admet-159	465	12	in	in	ADP
admet-159	465	13	the	the	DET
admet-159	465	14	inner	inner	ADJ
admet-159	465	15	chamber	chamber	NOUN
admet-159	465	16	;	;	PUNCT
admet-159	465	17	the	the	DET
admet-159	465	18	inner	inner	ADJ
admet-159	465	19	chamber	chamber	NOUN
admet-159	465	20	is	be	AUX
admet-159	465	21	inserted	insert	VERB
admet-159	465	22	in	in	ADP
admet-159	465	23	the	the	DET
admet-159	465	24	outer	outer	ADJ
admet-159	465	25	chamber	chamber	NOUN
admet-159	465	26	.	.	PUNCT
admet-159	466	1	the	the	DET
admet-159	466	2	monolayer	monolayer	NOUN
admet-159	466	3	epithelial	epithelial	ADJ
admet-159	466	4	cells	cell	NOUN
admet-159	466	5	have	have	VERB
admet-159	466	6	the	the	DET
admet-159	466	7	tight	tight	ADJ
admet-159	466	8	junctions	junction	NOUN
admet-159	466	9	between	between	ADP
admet-159	466	10	each	each	DET
admet-159	466	11	other	other	ADJ
admet-159	466	12	,	,	PUNCT
admet-159	466	13	which	which	PRON
admet-159	466	14	forms	form	VERB
admet-159	466	15	a	a	DET
admet-159	466	16	tight	tight	ADJ
admet-159	466	17	barrier	barrier	NOUN
admet-159	466	18	between	between	ADP
admet-159	466	19	in	in	ADP
admet-159	466	20	the	the	DET
admet-159	466	21	inner	inner	ADJ
admet-159	466	22	and	and	CCONJ
admet-159	466	23	outer	outer	ADJ
admet-159	466	24	chambers	chamber	NOUN
admet-159	466	25	.	.	PUNCT
admet-159	467	1	an	an	DET
admet-159	467	2	efflux	efflux	NOUN
admet-159	467	3	experiment	experiment	NOUN
admet-159	467	4	is	be	AUX
admet-159	467	5	illustrated	illustrate	VERB
admet-159	467	6	by	by	ADP
admet-159	467	7	adding	add	VERB
admet-159	467	8	a	a	PRON
admet-159	467	9	-	-	PUNCT
admet-159	467	10	syn	syn	NOUN
admet-159	467	11	into	into	ADP
admet-159	467	12	the	the	DET
admet-159	467	13	inner	inner	ADJ
admet-159	467	14	chamber	chamber	NOUN
admet-159	467	15	and	and	CCONJ
admet-159	467	16	quantifying	quantify	VERB
admet-159	467	17	a	a	PROPN
admet-159	467	18	-	-	PUNCT
admet-159	467	19	syn	syn	NOUN
admet-159	467	20	in	in	ADP
admet-159	467	21	the	the	DET
admet-159	467	22	outer	outer	ADJ
admet-159	467	23	chamber	chamber	NOUN
admet-159	467	24	.	.	PUNCT
admet-159	468	1	control	control	NOUN
admet-159	468	2	25	25	NUM
admet-159	468	3	μm	μm	NUM
admet-159	468	4	mn	mn	PROPN
admet-159	468	5	50	50	NUM
admet-159	468	6	μm	μm	NOUN
admet-159	468	7	mn	mn	PROPN
admet-159	468	8	100	100	NUM
admet-159	469	1	μm	μm	NOUN
admet-159	469	2	mn	mn	PROPN
admet-159	469	3	1	1	NUM
admet-159	469	4	2	2	NUM
admet-159	469	5	h	h	NOUN
admet-159	469	6	o	o	NOUN
admet-159	469	7	u	u	NOUN
admet-159	469	8	rs	rs	NOUN
admet-159	469	9	2	2	NUM
admet-159	469	10	4	4	NUM
admet-159	469	11	h	h	NOUN
admet-159	469	12	o	o	NOUN
admet-159	469	13	u	u	NOUN
admet-159	469	14	rs	rs	NOUN
admet-159	469	15	4	4	NUM
admet-159	469	16	8	8	NUM
admet-159	469	17	h	h	NOUN
admet-159	469	18	o	o	NOUN
admet-159	469	19	u	u	NOUN
admet-159	469	20	rs	rs	NOUN
admet-159	469	21	a	a	PRON
admet-159	469	22	)	)	PUNCT
admet-159	469	23	add	add	VERB
admet-159	469	24	a	a	DET
admet-159	469	25	-	-	PUNCT
admet-159	469	26	syn	syn	NOUN
admet-159	469	27	into	into	ADP
admet-159	469	28	inner	inner	ADJ
admet-159	469	29	chamber	chamber	NOUN
admet-159	469	30	determine	determine	VERB
admet-159	469	31	a	a	DET
admet-159	469	32	-	-	PUNCT
admet-159	469	33	syn	syn	NOUN
admet-159	469	34	in	in	ADP
admet-159	469	35	the	the	DET
admet-159	469	36	outer	outer	ADJ
admet-159	469	37	chamber	chamber	PROPN
admet-159	469	38	inner	inner	PROPN
admet-159	469	39	chamber	chamber	PROPN
admet-159	469	40	outer	outer	PROPN
admet-159	469	41	chamber	chamber	NOUN
admet-159	469	42	cells	cell	NOUN
admet-159	469	43	porous	porous	ADJ
admet-159	469	44	filter	filter	NOUN
admet-159	469	45	laminin	laminin	NOUN
admet-159	469	46	admet	admet	NOUN
admet-159	469	47	&	&	CCONJ
admet-159	469	48	dmpk	dmpk	PROPN
admet-159	469	49	3(1	3(1	NUM
admet-159	469	50	)	)	PUNCT
admet-159	469	51	(	(	PUNCT
admet-159	469	52	2015	2015	NUM
admet-159	469	53	)	)	PUNCT
admet-159	469	54	15	15	NUM
admet-159	469	55	-	-	SYM
admet-159	469	56	33	33	NUM
admet-159	469	57	effects	effect	NOUN
admet-159	469	58	of	of	ADP
admet-159	469	59	manganese	manganese	ADJ
admet-159	469	60	exposure	exposure	NOUN
admet-159	469	61	on	on	ADP
admet-159	469	62	expression	expression	NOUN
admet-159	469	63	and	and	CCONJ
admet-159	469	64	transport	transport	NOUN
admet-159	469	65	of	of	ADP
admet-159	469	66	-synuclein	-synuclein	PROPN
admet-159	469	67	doi	doi	NOUN
admet-159	469	68	:	:	PUNCT
admet-159	469	69	10.5599	10.5599	NUM
admet-159	469	70	/	/	SYM
admet-159	469	71	admet.3.1.159	admet.3.1.159	NUM
admet-159	469	72	33	33	NUM
admet-159	469	73	figure	figure	NOUN
admet-159	469	74	s2	s2	PROPN
admet-159	469	75	.	.	PUNCT
admet-159	469	76	dose	dose	NOUN
admet-159	469	77	-	-	PUNCT
admet-159	469	78	time	time	NOUN
admet-159	469	79	responses	response	NOUN
admet-159	469	80	of	of	ADP
admet-159	469	81	mn	mn	PROPN
admet-159	469	82	effect	effect	NOUN
admet-159	469	83	on	on	ADP
admet-159	469	84	a	a	DET
admet-159	469	85	-	-	PUNCT
admet-159	469	86	syn	syn	NOUN
admet-159	469	87	expression	expression	NOUN
admet-159	469	88	in	in	ADP
admet-159	469	89	primary	primary	ADJ
admet-159	469	90	choroidal	choroidal	ADJ
admet-159	469	91	epithelial	epithelial	ADJ
admet-159	469	92	cells	cell	NOUN
admet-159	469	93	in	in	ADP
admet-159	469	94	the	the	DET
admet-159	469	95	absence	absence	NOUN
admet-159	469	96	or	or	CCONJ
admet-159	469	97	presence	presence	NOUN
admet-159	469	98	of	of	ADP
admet-159	469	99	a	a	DET
admet-159	469	100	-	-	PUNCT
admet-159	469	101	syn	syn	NOUN
admet-159	469	102	.	.	PUNCT
admet-159	470	1	(	(	PUNCT
admet-159	470	2	a	a	NOUN
admet-159	470	3	)	)	PUNCT
admet-159	470	4	.	.	PUNCT
admet-159	471	1	ihc	ihc	PROPN
admet-159	471	2	staining	staining	NOUN
admet-159	471	3	of	of	ADP
admet-159	471	4	a	a	DET
admet-159	471	5	-	-	PUNCT
admet-159	471	6	syn	syn	NOUN
admet-159	471	7	in	in	ADP
admet-159	471	8	primary	primary	ADJ
admet-159	471	9	plexus	plexus	NOUN
admet-159	471	10	cells	cell	NOUN
admet-159	471	11	without	without	ADP
admet-159	471	12	added	add	VERB
admet-159	471	13	a	a	DET
admet-159	471	14	-	-	PUNCT
admet-159	471	15	syn	syn	NOUN
admet-159	471	16	.	.	PUNCT
admet-159	472	1	cells	cell	NOUN
admet-159	472	2	were	be	AUX
admet-159	472	3	treated	treat	VERB
admet-159	472	4	with	with	ADP
admet-159	472	5	various	various	ADJ
admet-159	472	6	concentrations	concentration	NOUN
admet-159	472	7	of	of	ADP
admet-159	472	8	mn	mn	PROPN
admet-159	472	9	or	or	CCONJ
admet-159	472	10	saline	saline	NOUN
admet-159	472	11	(	(	PUNCT
admet-159	472	12	control	control	NOUN
admet-159	472	13	)	)	PUNCT
admet-159	472	14	for	for	ADP
admet-159	472	15	12	12	NUM
admet-159	472	16	,	,	PUNCT
admet-159	472	17	24	24	NUM
admet-159	472	18	,	,	PUNCT
admet-159	472	19	or	or	CCONJ
admet-159	472	20	48	48	NUM
admet-159	472	21	h	h	NOUN
admet-159	472	22	and	and	CCONJ
admet-159	472	23	stained	stain	VERB
admet-159	472	24	for	for	ADP
admet-159	472	25	a	a	DET
admet-159	472	26	-	-	PUNCT
admet-159	472	27	syn	syn	NOUN
admet-159	472	28	.	.	PUNCT
admet-159	473	1	(	(	PUNCT
admet-159	473	2	b	b	NOUN
admet-159	473	3	)	)	PUNCT
admet-159	473	4	.	.	PUNCT
admet-159	474	1	cells	cell	NOUN
admet-159	474	2	were	be	AUX
admet-159	474	3	treated	treat	VERB
admet-159	474	4	with	with	ADP
admet-159	474	5	various	various	ADJ
admet-159	474	6	concentrations	concentration	NOUN
admet-159	474	7	of	of	ADP
admet-159	474	8	mn	mn	NOUN
admet-159	474	9	or	or	CCONJ
admet-159	474	10	saline	saline	VERB
admet-159	474	11	for	for	ADP
admet-159	474	12	12	12	NUM
admet-159	474	13	,	,	PUNCT
admet-159	474	14	24	24	NUM
admet-159	474	15	,	,	PUNCT
admet-159	474	16	or	or	CCONJ
admet-159	474	17	48	48	NUM
admet-159	474	18	h	h	NOUN
admet-159	474	19	,	,	PUNCT
admet-159	474	20	followed	follow	VERB
admet-159	474	21	by	by	ADP
admet-159	474	22	incubation	incubation	NOUN
admet-159	474	23	with	with	ADP
admet-159	474	24	0.5	0.5	NUM
admet-159	474	25	μm	μm	NOUN
admet-159	474	26	recombinant	recombinant	ADJ
admet-159	474	27	human	human	ADJ
admet-159	474	28	asyn	asyn	NOUN
admet-159	474	29	for	for	ADP
admet-159	474	30	2	2	NUM
admet-159	474	31	h.	h.	NOUN
admet-159	474	32	cells	cell	NOUN
admet-159	474	33	were	be	AUX
admet-159	474	34	stained	stain	VERB
admet-159	474	35	with	with	ADP
admet-159	474	36	primary	primary	ADJ
admet-159	474	37	anti	anti	ADJ
admet-159	474	38	-	-	ADJ
admet-159	474	39	a	a	DET
admet-159	474	40	-	-	PUNCT
admet-159	474	41	syn	syn	NOUN
admet-159	474	42	.	.	PUNCT
admet-159	475	1	a	a	DET
admet-159	475	2	typical	typical	ADJ
admet-159	475	3	study	study	NOUN
admet-159	475	4	of	of	ADP
admet-159	475	5	n	n	NOUN
admet-159	475	6	=	=	SYM
admet-159	475	7	4	4	NUM
admet-159	475	8	is	be	AUX
admet-159	475	9	presented	present	VERB
admet-159	475	10	.	.	PUNCT
admet-159	476	1	(	(	PUNCT
admet-159	476	2	c	c	NOUN
admet-159	476	3	)	)	PUNCT
admet-159	476	4	.	.	PUNCT
admet-159	477	1	confocal	confocal	ADJ
admet-159	477	2	quantification	quantification	NOUN
admet-159	477	3	of	of	ADP
admet-159	477	4	a	a	DET
admet-159	477	5	-	-	PUNCT
admet-159	477	6	syn	syn	NOUN
admet-159	477	7	.	.	PROPN
admet-159	477	8	for	for	ADP
admet-159	477	9	each	each	DET
admet-159	477	10	time	time	NOUN
admet-159	477	11	point	point	NOUN
admet-159	477	12	,	,	PUNCT
admet-159	477	13	the	the	DET
admet-159	477	14	data	datum	NOUN
admet-159	477	15	were	be	AUX
admet-159	477	16	compared	compare	VERB
admet-159	477	17	between	between	ADP
admet-159	477	18	cells	cell	NOUN
admet-159	477	19	with	with	ADP
admet-159	477	20	or	or	CCONJ
admet-159	477	21	without	without	ADP
admet-159	477	22	added	add	VERB
admet-159	477	23	a	a	PRON
admet-159	477	24	-	-	PUNCT
admet-159	477	25	syn	syn	PROPN
admet-159	477	26	.	.	PROPN
admet-159	477	27	data	datum	NOUN
admet-159	477	28	represent	represent	VERB
admet-159	477	29	mean	mean	PROPN
admet-159	477	30	±	±	NUM
admet-159	477	31	sd	sd	NOUN
admet-159	477	32	.	.	PUNCT
admet-159	478	1	n	n	NOUN
admet-159	479	1	=	=	SYM
admet-159	479	2	10	10	NUM
admet-159	479	3	-	-	SYM
admet-159	479	4	24	24	NUM
admet-159	479	5	.	.	PUNCT
admet-159	480	1	*	*	PUNCT
admet-159	480	2	:	:	PUNCT
admet-159	480	3	p	p	X
admet-159	480	4	<	<	X
admet-159	480	5	0.01	0.01	NUM
admet-159	480	6	,	,	PUNCT
admet-159	480	7	*	*	PUNCT
admet-159	480	8	*	*	PUNCT
admet-159	480	9	:	:	PUNCT
admet-159	481	1	p	p	X
admet-159	481	2	<	<	X
admet-159	481	3	0.001	0.001	NUM
admet-159	481	4	as	as	SCONJ
admet-159	481	5	compared	compare	VERB
admet-159	481	6	to	to	ADP
admet-159	481	7	the	the	DET
admet-159	481	8	data	datum	NOUN
admet-159	481	9	at	at	ADP
admet-159	481	10	the	the	DET
admet-159	481	11	same	same	ADJ
admet-159	481	12	time	time	NOUN
admet-159	481	13	point	point	NOUN
admet-159	481	14	without	without	ADP
admet-159	481	15	added	add	VERB
admet-159	481	16	a	a	DET
admet-159	481	17	-	-	PUNCT
admet-159	481	18	syn	syn	NOUN
admet-159	481	19	.	.	PROPN
admet-159	481	20	1	1	NUM
admet-159	481	21	2	2	NUM
admet-159	481	22	h	h	NOUN
admet-159	481	23	o	o	NOUN
admet-159	481	24	u	u	NOUN
admet-159	481	25	rs	rs	NOUN
admet-159	481	26	2	2	NUM
admet-159	481	27	4	4	NUM
admet-159	481	28	h	h	NOUN
admet-159	481	29	o	o	NOUN
admet-159	481	30	u	u	NOUN
admet-159	481	31	rs	rs	NOUN
admet-159	481	32	4	4	NUM
admet-159	481	33	8	8	NUM
admet-159	481	34	h	h	NOUN
admet-159	481	35	o	o	X
admet-159	481	36	u	u	NOUN
admet-159	481	37	rs	rs	NOUN
admet-159	481	38	control	control	NOUN
admet-159	481	39	+	+	CCONJ
admet-159	481	40	a	a	PROPN
admet-159	481	41	-	-	PUNCT
admet-159	481	42	syn	syn	NOUN
admet-159	481	43	25	25	NUM
admet-159	481	44	μm	μm	NUM
admet-159	481	45	mn	mn	PROPN
admet-159	481	46	+	+	CCONJ
admet-159	481	47	a	a	PROPN
admet-159	481	48	-	-	PUNCT
admet-159	481	49	syn	syn	NOUN
admet-159	481	50	50	50	NUM
admet-159	481	51	μm	μm	NOUN
admet-159	481	52	mn	mn	PROPN
admet-159	481	53	+	+	CCONJ
admet-159	481	54	a	a	PROPN
admet-159	481	55	-	-	PUNCT
admet-159	481	56	syn	syn	NOUN
admet-159	481	57	100	100	NUM
admet-159	481	58	μm	μm	NUM
admet-159	481	59	mn	mn	PROPN
admet-159	481	60	+	+	CCONJ
admet-159	481	61	a	a	PROPN
admet-159	481	62	-	-	PUNCT
admet-159	481	63	syn	syn	NOUN
admet-159	481	64	b	b	PROPN
admet-159	481	65	)	)	PUNCT
admet-159	481	66	c	c	NOUN
admet-159	481	67	)	)	PUNCT
admet-159	481	68	*	*	PUNCT
admet-159	482	1	*	*	PUNCT
admet-159	483	1	*	*	PUNCT
admet-159	483	2	*	*	PUNCT
admet-159	484	1	*	*	PUNCT
admet-159	484	2	*	*	PUNCT
admet-159	485	1	*	*	PUNCT
admet-159	485	2	*	*	PUNCT
admet-159	486	1	*	*	PUNCT
admet-159	486	2	*	*	PUNCT
admet-159	487	1	*	*	PUNCT
admet-159	487	2	*	*	PUNCT
admet-159	488	1	*	*	PUNCT
admet-159	488	2	*	*	PUNCT
admet-159	488	3	*	*	PUNCT