id	sid	tid	token	lemma	pos
admet-162	1	1	manuscript	manuscript	PROPN
admet-162	1	2	doi	doi	PROPN
admet-162	1	3	:	:	PUNCT
admet-162	1	4	10.5599	10.5599	NUM
admet-162	1	5	/	/	SYM
admet-162	1	6	admet.3.2.162	admet.3.2.162	ADP
admet-162	1	7	110	110	NUM
admet-162	1	8	admet	admet	X
admet-162	1	9	&	&	CCONJ
admet-162	1	10	dmpk	dmpk	PROPN
admet-162	1	11	3(2	3(2	NUM
admet-162	1	12	)	)	PUNCT
admet-162	1	13	(	(	PUNCT
admet-162	1	14	2015	2015	NUM
admet-162	1	15	)	)	PUNCT
admet-162	1	16	110	110	NUM
admet-162	1	17	-	-	SYM
admet-162	1	18	121	121	NUM
admet-162	1	19	;	;	PUNCT
admet-162	1	20	doi	doi	NOUN
admet-162	1	21	:	:	PUNCT
admet-162	1	22	10.5599	10.5599	NUM
admet-162	1	23	/	/	SYM
admet-162	1	24	admet.3.2.162	admet.3.2.162	ADV
admet-162	1	25	open	open	ADJ
admet-162	1	26	access	access	NOUN
admet-162	1	27	:	:	PUNCT
admet-162	1	28	issn	issn	PROPN
admet-162	1	29	:	:	PUNCT
admet-162	1	30	1848	1848	NUM
admet-162	1	31	-	-	SYM
admet-162	1	32	7718	7718	NUM
admet-162	1	33	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-162	1	34	review	review	VERB
admet-162	1	35	the	the	DET
admet-162	1	36	complexity	complexity	NOUN
admet-162	1	37	of	of	ADP
admet-162	1	38	roles	role	NOUN
admet-162	1	39	of	of	ADP
admet-162	1	40	p	p	NOUN
admet-162	1	41	-	-	PUNCT
admet-162	1	42	glycoprotein	glycoprotein	NOUN
admet-162	1	43	in	in	ADP
admet-162	1	44	refractory	refractory	NOUN
admet-162	1	45	epilepsy	epilepsy	NOUN
admet-162	1	46	:	:	PUNCT
admet-162	1	47	pharmacoresistance	pharmacoresistance	PROPN
admet-162	1	48	,	,	PUNCT
admet-162	1	49	epileptogenesis	epileptogenesis	NOUN
admet-162	1	50	,	,	PUNCT
admet-162	1	51	sudep	sudep	NOUN
admet-162	1	52	and	and	CCONJ
admet-162	1	53	relapsing	relapse	VERB
admet-162	1	54	marker	marker	NOUN
admet-162	1	55	after	after	ADP
admet-162	1	56	surgical	surgical	ADJ
admet-162	1	57	treatment	treatment	NOUN
admet-162	1	58	alberto	alberto	NOUN
admet-162	1	59	lazarowski1,2,£	lazarowski1,2,£	PROPN
admet-162	1	60	*	*	PROPN
admet-162	1	61	,	,	PUNCT
admet-162	1	62	liliana	liliana	PROPN
admet-162	1	63	czornyj2,3,£	czornyj2,3,£	PROPN
admet-162	1	64	,	,	PUNCT
admet-162	1	65	luisa	luisa	PROPN
admet-162	1	66	rocha4,£	rocha4,£	PROPN
admet-162	1	67	1	1	NUM
admet-162	1	68	infibioc	infibioc	NOUN
admet-162	1	69	,	,	PUNCT
admet-162	1	70	ffyb	ffyb	NOUN
admet-162	1	71	-	-	PUNCT
admet-162	1	72	university	university	NOUN
admet-162	1	73	of	of	ADP
admet-162	1	74	buenos	buenos	PROPN
admet-162	1	75	aires	aires	PROPN
admet-162	1	76	(	(	PUNCT
admet-162	1	77	uba	uba	PROPN
admet-162	1	78	)	)	PUNCT
admet-162	1	79	,	,	PUNCT
admet-162	1	80	junin	junin	PROPN
admet-162	1	81	956	956	NUM
admet-162	1	82	(	(	PUNCT
admet-162	1	83	1113	1113	NUM
admet-162	1	84	)	)	PUNCT
admet-162	1	85	,	,	PUNCT
admet-162	1	86	caba	caba	PROPN
admet-162	1	87	,	,	PUNCT
admet-162	1	88	argentina	argentina	PROPN
admet-162	1	89	2	2	NUM
admet-162	1	90	fundacion	fundacion	NOUN
admet-162	1	91	investigar	investigar	NOUN
admet-162	1	92	,	,	PUNCT
admet-162	1	93	riobamba	riobamba	VERB
admet-162	1	94	426	426	NUM
admet-162	1	95	p-15	p-15	NOUN
admet-162	1	96	(	(	PUNCT
admet-162	1	97	1025	1025	NUM
admet-162	1	98	)	)	PUNCT
admet-162	1	99	,	,	PUNCT
admet-162	1	100	caba	caba	PROPN
admet-162	1	101	,	,	PUNCT
admet-162	1	102	argentina	argentina	PROPN
admet-162	1	103	3	3	NUM
admet-162	1	104	servicio	servicio	PROPN
admet-162	1	105	de	de	X
admet-162	1	106	neurologia	neurologia	PROPN
admet-162	1	107	,	,	PUNCT
admet-162	2	1	hospital	hospital	NOUN
admet-162	2	2	juan	juan	PROPN
admet-162	2	3	p.	p.	PROPN
admet-162	2	4	garraham	garraham	PROPN
admet-162	2	5	,	,	PUNCT
admet-162	2	6	combate	combate	PROPN
admet-162	2	7	de	de	PROPN
admet-162	2	8	los	los	PROPN
admet-162	2	9	pozos	pozos	PROPN
admet-162	2	10	1881	1881	NUM
admet-162	2	11	(	(	PUNCT
admet-162	2	12	1245	1245	NUM
admet-162	2	13	)	)	PUNCT
admet-162	2	14	,	,	PUNCT
admet-162	2	15	caba	caba	PROPN
admet-162	2	16	,	,	PUNCT
admet-162	2	17	argentina	argentina	PROPN
admet-162	2	18	.	.	PROPN
admet-162	3	1	4	4	NUM
admet-162	3	2	pharmacobiology	pharmacobiology	NOUN
admet-162	3	3	department	department	NOUN
admet-162	3	4	,	,	PUNCT
admet-162	3	5	center	center	NOUN
admet-162	3	6	for	for	ADP
admet-162	3	7	research	research	NOUN
admet-162	3	8	and	and	CCONJ
admet-162	3	9	advanced	advanced	ADJ
admet-162	3	10	studies	study	NOUN
admet-162	3	11	,	,	PUNCT
admet-162	3	12	df	df	PROPN
admet-162	3	13	,	,	PUNCT
admet-162	3	14	mexico	mexico	PROPN
admet-162	3	15	.	.	PUNCT
admet-162	4	1	£	£	NOUN
admet-162	4	2	members	member	NOUN
admet-162	4	3	of	of	ADP
admet-162	4	4	geniar	geniar	PROPN
admet-162	4	5	(	(	PUNCT
admet-162	4	6	cyted	cyte	VERB
admet-162	4	7	610rt0405	610rt0405	NUM
admet-162	4	8	)	)	PUNCT
admet-162	4	9	*	*	PUNCT
admet-162	4	10	corresponding	correspond	VERB
admet-162	4	11	author	author	NOUN
admet-162	4	12	:	:	PUNCT
admet-162	4	13	e	e	NOUN
admet-162	4	14	-	-	NOUN
admet-162	4	15	mail	mail	NOUN
admet-162	4	16	:	:	PUNCT
admet-162	5	1	alazarowski@gmail.com	alazarowski@gmail.com	PROPN
admet-162	5	2	;	;	PUNCT
admet-162	5	3	tel	tel	PROPN
admet-162	5	4	+54	+54	PROPN
admet-162	5	5	-	-	PUNCT
admet-162	5	6	11	11	NUM
admet-162	5	7	-	-	PUNCT
admet-162	5	8	4304	4304	NUM
admet-162	5	9	-	-	PUNCT
admet-162	5	10	2611	2611	NUM
admet-162	5	11	received	receive	VERB
admet-162	5	12	:	:	PUNCT
admet-162	5	13	january	january	PROPN
admet-162	5	14	29	29	NUM
admet-162	5	15	,	,	PUNCT
admet-162	5	16	2015	2015	NUM
admet-162	5	17	;	;	PUNCT
admet-162	5	18	revised	revise	VERB
admet-162	5	19	:	:	PUNCT
admet-162	5	20	may	may	AUX
admet-162	5	21	04	04	NUM
admet-162	5	22	,	,	PUNCT
admet-162	5	23	2015	2015	NUM
admet-162	5	24	;	;	PUNCT
admet-162	5	25	published	publish	VERB
admet-162	5	26	:	:	PUNCT
admet-162	5	27	july	july	PROPN
admet-162	5	28	01	01	NUM
admet-162	5	29	,	,	PUNCT
admet-162	5	30	2015	2015	NUM
admet-162	5	31	abstract	abstract	NOUN
admet-162	5	32	as	as	SCONJ
admet-162	5	33	described	describe	VERB
admet-162	5	34	initially	initially	ADV
admet-162	5	35	from	from	ADP
admet-162	5	36	clinical	clinical	ADJ
admet-162	5	37	and	and	CCONJ
admet-162	5	38	experimental	experimental	ADJ
admet-162	5	39	studies	study	NOUN
admet-162	5	40	,	,	PUNCT
admet-162	5	41	p	p	NOUN
admet-162	5	42	-	-	PUNCT
admet-162	5	43	glycoprotein	glycoprotein	NOUN
admet-162	5	44	(	(	PUNCT
admet-162	5	45	p	p	NOUN
admet-162	5	46	-	-	PUNCT
admet-162	5	47	gp	gp	NOUN
admet-162	5	48	)	)	PUNCT
admet-162	5	49	plays	play	VERB
admet-162	5	50	a	a	DET
admet-162	5	51	central	central	ADJ
admet-162	5	52	role	role	NOUN
admet-162	5	53	in	in	ADP
admet-162	5	54	the	the	DET
admet-162	5	55	pharmacoresistance	pharmacoresistance	NOUN
admet-162	5	56	of	of	ADP
admet-162	5	57	epilepsy	epilepsy	PROPN
admet-162	5	58	,	,	PUNCT
admet-162	5	59	acting	act	VERB
admet-162	5	60	by	by	ADP
admet-162	5	61	efflux	efflux	NOUN
admet-162	5	62	of	of	ADP
admet-162	5	63	aeds	aed	NOUN
admet-162	5	64	mainly	mainly	ADV
admet-162	5	65	at	at	ADP
admet-162	5	66	blood	blood	NOUN
admet-162	5	67	brain	brain	NOUN
admet-162	5	68	barrier	barrier	NOUN
admet-162	5	69	(	(	PUNCT
admet-162	5	70	bbb	bbb	NOUN
admet-162	5	71	)	)	PUNCT
admet-162	5	72	level	level	NOUN
admet-162	5	73	.	.	PUNCT
admet-162	6	1	however	however	ADV
admet-162	6	2	,	,	PUNCT
admet-162	6	3	repetitive	repetitive	ADJ
admet-162	6	4	seizures	seizure	NOUN
admet-162	6	5	can	can	AUX
admet-162	6	6	produce	produce	VERB
admet-162	6	7	both	both	DET
admet-162	6	8	brain	brain	NOUN
admet-162	6	9	and	and	CCONJ
admet-162	6	10	heart	heart	NOUN
admet-162	6	11	p	p	NOUN
admet-162	6	12	-	-	PUNCT
admet-162	6	13	gp	gp	NOUN
admet-162	6	14	overexpression	overexpression	NOUN
admet-162	6	15	.	.	PUNCT
admet-162	7	1	because	because	SCONJ
admet-162	7	2	p	p	NOUN
admet-162	7	3	-	-	PUNCT
admet-162	7	4	gp	gp	NOUN
admet-162	7	5	activity	activity	NOUN
admet-162	7	6	induces	induce	VERB
admet-162	7	7	membrane	membrane	ADJ
admet-162	7	8	depolarization	depolarization	NOUN
admet-162	7	9	,	,	PUNCT
admet-162	7	10	its	its	PRON
admet-162	7	11	neuronal	neuronal	ADJ
admet-162	7	12	expression	expression	NOUN
admet-162	7	13	could	could	AUX
admet-162	7	14	be	be	AUX
admet-162	7	15	acting	act	VERB
admet-162	7	16	in	in	ADP
admet-162	7	17	the	the	DET
admet-162	7	18	intrinsic	intrinsic	ADJ
admet-162	7	19	mechanism	mechanism	NOUN
admet-162	7	20	of	of	ADP
admet-162	7	21	epileptogenesis	epileptogenesis	NOUN
admet-162	7	22	,	,	PUNCT
admet-162	7	23	and	and	CCONJ
admet-162	7	24	its	its	PRON
admet-162	7	25	heart	heart	NOUN
admet-162	7	26	expression	expression	NOUN
admet-162	7	27	,	,	PUNCT
admet-162	7	28	can	can	AUX
admet-162	7	29	be	be	AUX
admet-162	7	30	a	a	DET
admet-162	7	31	high	high	ADJ
admet-162	7	32	risk	risk	NOUN
admet-162	7	33	factor	factor	NOUN
admet-162	7	34	of	of	ADP
admet-162	7	35	death	death	NOUN
admet-162	7	36	,	,	PUNCT
admet-162	7	37	after	after	ADP
admet-162	7	38	severe	severe	ADJ
admet-162	7	39	-	-	PUNCT
admet-162	7	40	continuo	continuo	NOUN
admet-162	7	41	convulsive	convulsive	ADJ
admet-162	7	42	stresses	stress	NOUN
admet-162	7	43	as	as	ADP
admet-162	7	44	in	in	ADP
admet-162	7	45	fatal	fatal	ADJ
admet-162	7	46	status	status	NOUN
admet-162	7	47	epilepticus	epilepticus	VERB
admet-162	7	48	or	or	CCONJ
admet-162	7	49	in	in	ADP
admet-162	7	50	sudep	sudep	NOUN
admet-162	7	51	.	.	PUNCT
admet-162	8	1	additionally	additionally	ADV
admet-162	8	2	,	,	PUNCT
admet-162	8	3	because	because	SCONJ
admet-162	8	4	p	p	X
admet-162	8	5	-	-	PUNCT
admet-162	8	6	gp	gp	NOUN
admet-162	8	7	is	be	AUX
admet-162	8	8	also	also	ADV
admet-162	8	9	a	a	DET
admet-162	8	10	stem	stem	NOUN
admet-162	8	11	cell	cell	NOUN
admet-162	8	12	marker	marker	NOUN
admet-162	8	13	,	,	PUNCT
admet-162	8	14	we	we	PRON
admet-162	8	15	suggests	suggest	VERB
admet-162	8	16	that	that	SCONJ
admet-162	8	17	its	its	PRON
admet-162	8	18	constitutive	constitutive	ADJ
admet-162	8	19	overexpression	overexpression	NOUN
admet-162	8	20	in	in	ADP
admet-162	8	21	dysplastic	dysplastic	ADJ
admet-162	8	22	neurons	neuron	NOUN
admet-162	8	23	from	from	ADP
admet-162	8	24	brain	brain	NOUN
admet-162	8	25	epileptogenic	epileptogenic	ADJ
admet-162	8	26	areas	area	NOUN
admet-162	8	27	observed	observe	VERB
admet-162	8	28	in	in	ADP
admet-162	8	29	patients	patient	NOUN
admet-162	8	30	with	with	ADP
admet-162	8	31	refractory	refractory	NOUN
admet-162	8	32	epilepsies	epilepsy	NOUN
admet-162	8	33	,	,	PUNCT
admet-162	8	34	should	should	AUX
admet-162	8	35	be	be	AUX
admet-162	8	36	addressed	address	VERB
admet-162	8	37	as	as	ADP
admet-162	8	38	a	a	DET
admet-162	8	39	risk	risk	NOUN
admet-162	8	40	factor	factor	NOUN
admet-162	8	41	of	of	ADP
admet-162	8	42	seizures	seizure	NOUN
admet-162	8	43	relapse	relapse	VERB
admet-162	8	44	after	after	ADP
admet-162	8	45	surgical	surgical	ADJ
admet-162	8	46	treatment	treatment	NOUN
admet-162	8	47	.	.	PUNCT
admet-162	9	1	here	here	ADV
admet-162	9	2	we	we	PRON
admet-162	9	3	discuss	discuss	VERB
admet-162	9	4	these	these	DET
admet-162	9	5	concepts	concept	NOUN
admet-162	9	6	,	,	PUNCT
admet-162	9	7	based	base	VERB
admet-162	9	8	on	on	ADP
admet-162	9	9	our	our	PRON
admet-162	9	10	own	own	ADJ
admet-162	9	11	clinical	clinical	ADJ
admet-162	9	12	and	and	CCONJ
admet-162	9	13	experimental	experimental	ADJ
admet-162	9	14	experiences	experience	NOUN
admet-162	9	15	,	,	PUNCT
admet-162	9	16	and	and	CCONJ
admet-162	9	17	reviewing	review	VERB
admet-162	9	18	the	the	DET
admet-162	9	19	current	current	ADJ
admet-162	9	20	literature	literature	NOUN
admet-162	9	21	on	on	ADP
admet-162	9	22	these	these	DET
admet-162	9	23	subjects	subject	NOUN
admet-162	9	24	.	.	PUNCT
admet-162	10	1	keywords	keyword	VERB
admet-162	10	2	p	p	NOUN
admet-162	10	3	-	-	PUNCT
admet-162	10	4	glycoprotein	glycoprotein	NOUN
admet-162	10	5	;	;	PUNCT
admet-162	10	6	membrane	membrane	NOUN
admet-162	10	7	depolarization	depolarization	NOUN
admet-162	10	8	;	;	PUNCT
admet-162	10	9	drug	drug	NOUN
admet-162	10	10	resistance	resistance	NOUN
admet-162	10	11	;	;	PUNCT
admet-162	10	12	sudep	sudep	NOUN
admet-162	10	13	,	,	PUNCT
admet-162	10	14	biomarker	biomarker	NOUN
admet-162	10	15	,	,	PUNCT
admet-162	10	16	long	long	ADJ
admet-162	10	17	-	-	PUNCT
admet-162	10	18	term	term	NOUN
admet-162	10	19	relapse	relapse	NOUN
admet-162	10	20	“	"	PUNCT
admet-162	10	21	what	what	PRON
admet-162	10	22	is	be	AUX
admet-162	10	23	a	a	DET
admet-162	10	24	seizure	seizure	NOUN
admet-162	10	25	and	and	CCONJ
admet-162	10	26	what	what	PRON
admet-162	10	27	is	be	AUX
admet-162	10	28	epilepsy	epilepsy	ADJ
admet-162	10	29	?	?	PUNCT
admet-162	10	30	”	"	PUNCT
admet-162	10	31	seizures	seizure	NOUN
admet-162	10	32	and	and	CCONJ
admet-162	10	33	epilepsy	epilepsy	NOUN
admet-162	10	34	are	be	AUX
admet-162	10	35	not	not	PART
admet-162	10	36	the	the	DET
admet-162	10	37	same	same	ADJ
admet-162	10	38	.	.	PUNCT
admet-162	11	1	it	it	PRON
admet-162	11	2	is	be	AUX
admet-162	11	3	defined	define	VERB
admet-162	11	4	that	that	SCONJ
admet-162	11	5	seizure	seizure	NOUN
admet-162	11	6	as	as	ADP
admet-162	11	7	“	"	PUNCT
admet-162	11	8	the	the	DET
admet-162	11	9	abnormal	abnormal	ADJ
admet-162	11	10	excessive	excessive	ADJ
admet-162	11	11	or	or	CCONJ
admet-162	11	12	synchronous	synchronous	ADJ
admet-162	11	13	neuronal	neuronal	ADJ
admet-162	11	14	activity	activity	NOUN
admet-162	11	15	in	in	ADP
admet-162	11	16	the	the	DET
admet-162	11	17	brain	brain	NOUN
admet-162	11	18	”	"	PUNCT
admet-162	11	19	that	that	PRON
admet-162	11	20	can	can	AUX
admet-162	11	21	be	be	AUX
admet-162	11	22	produced	produce	VERB
admet-162	11	23	secondary	secondary	ADJ
admet-162	11	24	to	to	ADP
admet-162	11	25	a	a	DET
admet-162	11	26	wide	wide	ADJ
admet-162	11	27	spectrum	spectrum	NOUN
admet-162	11	28	of	of	ADP
admet-162	11	29	injuries	injury	NOUN
admet-162	11	30	.	.	PUNCT
admet-162	12	1	however	however	ADV
admet-162	12	2	,	,	PUNCT
admet-162	12	3	“	"	PUNCT
admet-162	12	4	epileptic	epileptic	ADJ
admet-162	12	5	seizures	seizure	NOUN
admet-162	12	6	”	"	PUNCT
admet-162	12	7	are	be	AUX
admet-162	12	8	produced	produce	VERB
admet-162	12	9	spontaneously	spontaneously	ADV
admet-162	12	10	,	,	PUNCT
admet-162	12	11	so	so	ADV
admet-162	12	12	,	,	PUNCT
admet-162	12	13	a	a	DET
admet-162	12	14	seizure	seizure	NOUN
admet-162	12	15	is	be	AUX
admet-162	12	16	an	an	DET
admet-162	12	17	event	event	NOUN
admet-162	12	18	and	and	CCONJ
admet-162	12	19	epilepsy	epilepsy	NOUN
admet-162	12	20	is	be	AUX
admet-162	12	21	a	a	DET
admet-162	12	22	disorder	disorder	NOUN
admet-162	12	23	involving	involve	VERB
admet-162	12	24	recurrent	recurrent	ADJ
admet-162	12	25	unprovoked	unprovoked	ADJ
admet-162	12	26	seizures	seizure	NOUN
admet-162	12	27	.	.	PUNCT
admet-162	13	1	after	after	ADP
admet-162	13	2	several	several	ADJ
admet-162	13	3	years	year	NOUN
admet-162	13	4	of	of	ADP
admet-162	13	5	deliberations	deliberation	NOUN
admet-162	13	6	on	on	ADP
admet-162	13	7	this	this	DET
admet-162	13	8	issue	issue	NOUN
admet-162	13	9	have	have	AUX
admet-162	13	10	now	now	ADV
admet-162	13	11	been	be	AUX
admet-162	13	12	published	publish	VERB
admet-162	13	13	the	the	DET
admet-162	13	14	result	result	NOUN
admet-162	13	15	from	from	ADP
admet-162	13	16	international	international	ADJ
admet-162	13	17	league	league	NOUN
admet-162	13	18	against	against	ADP
admet-162	13	19	epilepsy	epilepsy	NOUN
admet-162	13	20	(	(	PUNCT
admet-162	13	21	ilae	ilae	NOUN
admet-162	13	22	)	)	PUNCT
admet-162	13	23	commissioned	commission	VERB
admet-162	13	24	second	second	ADJ
admet-162	13	25	task	task	NOUN
admet-162	13	26	force	force	NOUN
admet-162	13	27	,	,	PUNCT
admet-162	13	28	to	to	PART
admet-162	13	29	develop	develop	VERB
admet-162	13	30	a	a	DET
admet-162	13	31	practical	practical	ADJ
admet-162	13	32	(	(	PUNCT
admet-162	13	33	operational	operational	ADJ
admet-162	13	34	)	)	PUNCT
admet-162	13	35	definition	definition	NOUN
admet-162	13	36	of	of	ADP
admet-162	13	37	epilepsy	epilepsy	NOUN
admet-162	13	38	,	,	PUNCT
admet-162	13	39	designed	design	VERB
admet-162	13	40	for	for	ADP
admet-162	13	41	use	use	NOUN
admet-162	13	42	by	by	ADP
admet-162	13	43	doctors	doctor	NOUN
admet-162	13	44	and	and	CCONJ
admet-162	13	45	patients	patient	NOUN
admet-162	13	46	[	[	X
admet-162	13	47	1	1	NUM
admet-162	13	48	]	]	PUNCT
admet-162	13	49	,	,	PUNCT
admet-162	13	50	and	and	CCONJ
admet-162	13	51	adopted	adopt	VERB
admet-162	13	52	as	as	ADP
admet-162	13	53	a	a	DET
admet-162	13	54	position	position	NOUN
admet-162	13	55	of	of	ADP
admet-162	13	56	the	the	DET
admet-162	13	57	ilae	ilae	NOUN
admet-162	13	58	.	.	PUNCT
admet-162	14	1	some	some	DET
admet-162	14	2	comments	comment	NOUN
admet-162	14	3	were	be	AUX
admet-162	14	4	published	publish	VERB
admet-162	14	5	to	to	ADP
admet-162	14	6	better	well	ADJ
admet-162	14	7	understanding	understanding	NOUN
admet-162	14	8	of	of	ADP
admet-162	14	9	this	this	DET
admet-162	14	10	definition	definition	NOUN
admet-162	14	11	,	,	PUNCT
admet-162	14	12	however	however	ADV
admet-162	14	13	,	,	PUNCT
admet-162	14	14	it	it	PRON
admet-162	14	15	is	be	AUX
admet-162	14	16	limited	limit	VERB
admet-162	14	17	to	to	ADP
admet-162	14	18	a	a	DET
admet-162	14	19	observational	observational	ADJ
admet-162	14	20	clinical	clinical	ADJ
admet-162	14	21	level	level	NOUN
admet-162	14	22	[	[	X
admet-162	14	23	2,3	2,3	NUM
admet-162	14	24	]	]	PUNCT
admet-162	14	25	,	,	PUNCT
admet-162	14	26	and	and	CCONJ
admet-162	14	27	not	not	PART
admet-162	14	28	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-162	14	29	mailto:alazarowski@gmail.com	mailto:alazarowski@gmail.com	X
admet-162	15	1	admet	admet	PROPN
admet-162	15	2	&	&	CCONJ
admet-162	15	3	dmpk	dmpk	PROPN
admet-162	15	4	3(2	3(2	NUM
admet-162	15	5	)	)	PUNCT
admet-162	15	6	(	(	PUNCT
admet-162	15	7	2015	2015	NUM
admet-162	15	8	)	)	PUNCT
admet-162	15	9	110	110	NUM
admet-162	15	10	-	-	SYM
admet-162	15	11	121	121	NUM
admet-162	15	12	the	the	DET
admet-162	15	13	roles	role	NOUN
admet-162	15	14	of	of	ADP
admet-162	15	15	p	p	NOUN
admet-162	15	16	-	-	PUNCT
admet-162	15	17	gp	gp	NOUN
admet-162	15	18	in	in	ADP
admet-162	15	19	refractory	refractory	NOUN
admet-162	15	20	epilepsy	epilepsy	NOUN
admet-162	15	21	doi	doi	NOUN
admet-162	15	22	:	:	PUNCT
admet-162	15	23	10.5599	10.5599	NUM
admet-162	15	24	/	/	SYM
admet-162	15	25	admet.3.2.162	admet.3.2.162	ADP
admet-162	15	26	111	111	NUM
admet-162	15	27	describe	describe	VERB
admet-162	15	28	the	the	DET
admet-162	15	29	cellular	cellular	ADJ
admet-162	15	30	or	or	CCONJ
admet-162	15	31	sub	sub	ADJ
admet-162	15	32	-	-	ADJ
admet-162	15	33	cellular	cellular	ADJ
admet-162	15	34	mechanistic	mechanistic	ADJ
admet-162	15	35	process	process	NOUN
admet-162	15	36	that	that	PRON
admet-162	15	37	involve	involve	VERB
admet-162	15	38	alterations	alteration	NOUN
admet-162	15	39	on	on	ADP
admet-162	15	40	functional	functional	ADJ
admet-162	15	41	properties	property	NOUN
admet-162	15	42	of	of	ADP
admet-162	15	43	the	the	DET
admet-162	15	44	neuronal	neuronal	ADJ
admet-162	15	45	membrane	membrane	NOUN
admet-162	15	46	.	.	PUNCT
admet-162	16	1	epilepsy	epilepsy	NOUN
admet-162	16	2	is	be	AUX
admet-162	16	3	the	the	DET
admet-162	16	4	second	second	ADJ
admet-162	16	5	most	most	ADV
admet-162	16	6	common	common	ADJ
admet-162	16	7	neurological	neurological	ADJ
admet-162	16	8	disorder	disorder	NOUN
admet-162	16	9	after	after	ADP
admet-162	16	10	cerebrovascular	cerebrovascular	ADJ
admet-162	16	11	accident	accident	NOUN
admet-162	16	12	(	(	PUNCT
admet-162	16	13	cva	cva	PROPN
admet-162	16	14	)	)	PUNCT
admet-162	16	15	or	or	CCONJ
admet-162	16	16	stroke	stroke	NOUN
admet-162	16	17	,	,	PUNCT
admet-162	16	18	and	and	CCONJ
admet-162	16	19	it	it	PRON
admet-162	16	20	is	be	AUX
admet-162	16	21	estimated	estimate	VERB
admet-162	16	22	that	that	SCONJ
admet-162	16	23	approximately	approximately	ADV
admet-162	16	24	~1.0	~1.0	ADP
admet-162	16	25	-	-	SYM
admet-162	16	26	2.0	2.0	NUM
admet-162	16	27	%	%	NOUN
admet-162	16	28	of	of	ADP
admet-162	16	29	the	the	DET
admet-162	16	30	population	population	NOUN
admet-162	16	31	is	be	AUX
admet-162	16	32	affected	affect	VERB
admet-162	16	33	by	by	ADP
admet-162	16	34	different	different	ADJ
admet-162	16	35	forms	form	NOUN
admet-162	16	36	of	of	ADP
admet-162	16	37	epilepsy	epilepsy	NOUN
admet-162	16	38	.	.	PUNCT
admet-162	17	1	interestingly	interestingly	ADV
admet-162	17	2	,	,	PUNCT
admet-162	17	3	near	near	ADP
admet-162	17	4	30	30	NUM
admet-162	17	5	%	%	NOUN
admet-162	17	6	of	of	ADP
admet-162	17	7	epilepsies	epilepsy	NOUN
admet-162	17	8	,	,	PUNCT
admet-162	17	9	have	have	VERB
admet-162	17	10	identifiable	identifiable	ADJ
admet-162	17	11	injuries	injury	NOUN
admet-162	17	12	to	to	ADP
admet-162	17	13	the	the	DET
admet-162	17	14	brain	brain	NOUN
admet-162	17	15	that	that	PRON
admet-162	17	16	triggered	trigger	VERB
admet-162	17	17	the	the	DET
admet-162	17	18	development	development	NOUN
admet-162	17	19	of	of	ADP
admet-162	17	20	the	the	DET
admet-162	17	21	named	name	VERB
admet-162	17	22	symptomatic	symptomatic	ADJ
admet-162	17	23	epilepsies	epilepsy	NOUN
admet-162	17	24	[	[	X
admet-162	17	25	4	4	NUM
admet-162	17	26	]	]	PUNCT
admet-162	17	27	.	.	PUNCT
admet-162	18	1	so	so	ADV
admet-162	18	2	,	,	PUNCT
admet-162	18	3	a	a	DET
admet-162	18	4	non	non	ADJ
admet-162	18	5	-	-	ADJ
admet-162	18	6	specific	specific	ADJ
admet-162	18	7	damaging	damaging	ADJ
admet-162	18	8	factor	factor	NOUN
admet-162	18	9	producing	produce	VERB
admet-162	18	10	a	a	DET
admet-162	18	11	brain	brain	NOUN
admet-162	18	12	injury	injury	NOUN
admet-162	18	13	can	can	AUX
admet-162	18	14	develop	develop	VERB
admet-162	18	15	symptomatic	symptomatic	ADJ
admet-162	18	16	epilepsy	epilepsy	NOUN
admet-162	18	17	after	after	ADP
admet-162	18	18	a	a	DET
admet-162	18	19	very	very	ADV
admet-162	18	20	complex	complex	ADJ
admet-162	18	21	subclinical	subclinical	ADJ
admet-162	18	22	process	process	NOUN
admet-162	18	23	,	,	PUNCT
admet-162	18	24	which	which	PRON
admet-162	18	25	links	link	VERB
admet-162	18	26	this	this	PRON
admet-162	18	27	mentioned	mention	VERB
admet-162	18	28	first	first	ADJ
admet-162	18	29	insult	insult	NOUN
admet-162	18	30	with	with	ADP
admet-162	18	31	the	the	DET
admet-162	18	32	clinically	clinically	ADV
admet-162	18	33	expressed	express	VERB
admet-162	18	34	first	first	ADJ
admet-162	18	35	spontaneous	spontaneous	ADJ
admet-162	18	36	epileptic	epileptic	ADJ
admet-162	18	37	seizure	seizure	NOUN
admet-162	18	38	.	.	PUNCT
admet-162	19	1	and	and	CCONJ
admet-162	19	2	this	this	DET
admet-162	19	3	particular	particular	ADJ
admet-162	19	4	and	and	CCONJ
admet-162	19	5	multifactorial	multifactorial	ADJ
admet-162	19	6	process	process	NOUN
admet-162	19	7	is	be	AUX
admet-162	19	8	recognized	recognize	VERB
admet-162	19	9	as	as	ADP
admet-162	19	10	latency	latency	NOUN
admet-162	19	11	phase	phase	NOUN
admet-162	19	12	or	or	CCONJ
admet-162	19	13	“	"	PUNCT
admet-162	19	14	epileptogenesis	epileptogenesis	NOUN
admet-162	19	15	”	"	PUNCT
admet-162	19	16	.	.	PUNCT
admet-162	20	1	this	this	DET
admet-162	20	2	cellular	cellular	ADJ
admet-162	20	3	/	/	SYM
admet-162	20	4	molecular	molecular	ADJ
admet-162	20	5	phenomenon	phenomenon	NOUN
admet-162	20	6	is	be	AUX
admet-162	20	7	started	start	VERB
admet-162	20	8	after	after	ADP
admet-162	20	9	the	the	DET
admet-162	20	10	brain	brain	NOUN
admet-162	20	11	injury	injury	NOUN
admet-162	20	12	and	and	CCONJ
admet-162	20	13	can	can	AUX
admet-162	20	14	be	be	AUX
admet-162	20	15	facilitated	facilitate	VERB
admet-162	20	16	by	by	ADP
admet-162	20	17	some	some	DET
admet-162	20	18	conditions	condition	NOUN
admet-162	20	19	as	as	ADP
admet-162	20	20	age	age	NOUN
admet-162	20	21	,	,	PUNCT
admet-162	20	22	co	co	NOUN
admet-162	20	23	-	-	NOUN
admet-162	20	24	morbidity	morbidity	NOUN
admet-162	20	25	,	,	PUNCT
admet-162	20	26	medications	medication	NOUN
admet-162	20	27	,	,	PUNCT
admet-162	20	28	etc	etc	X
admet-162	20	29	.	.	X
admet-162	20	30	blood	blood	NOUN
admet-162	20	31	brain	brain	NOUN
admet-162	20	32	barrier	barrier	NOUN
admet-162	20	33	(	(	PUNCT
admet-162	20	34	bbb	bbb	NOUN
admet-162	20	35	)	)	PUNCT
admet-162	20	36	damage	damage	NOUN
admet-162	20	37	,	,	PUNCT
admet-162	20	38	angiogenesis	angiogenesis	NOUN
admet-162	20	39	,	,	PUNCT
admet-162	20	40	gliosis	gliosis	NOUN
admet-162	20	41	,	,	PUNCT
admet-162	20	42	inflammation	inflammation	NOUN
admet-162	20	43	,	,	PUNCT
admet-162	20	44	axonal	axonal	ADJ
admet-162	20	45	sprouting	sprouting	NOUN
admet-162	20	46	or	or	CCONJ
admet-162	20	47	injury	injury	NOUN
admet-162	20	48	,	,	PUNCT
admet-162	20	49	acquired	acquire	VERB
admet-162	20	50	channelopathies	channelopathie	NOUN
admet-162	20	51	,	,	PUNCT
admet-162	20	52	and	and	CCONJ
admet-162	20	53	changes	change	NOUN
admet-162	20	54	of	of	ADP
admet-162	20	55	dendritic	dendritic	ADJ
admet-162	20	56	plasticity	plasticity	NOUN
admet-162	20	57	,	,	PUNCT
admet-162	20	58	are	be	AUX
admet-162	20	59	some	some	PRON
admet-162	20	60	of	of	ADP
admet-162	20	61	long	long	ADJ
admet-162	20	62	list	list	NOUN
admet-162	20	63	of	of	ADP
admet-162	20	64	modifications	modification	NOUN
admet-162	20	65	observed	observe	VERB
admet-162	20	66	during	during	ADP
admet-162	20	67	this	this	DET
admet-162	20	68	latency	latency	NOUN
admet-162	20	69	phase	phase	NOUN
admet-162	20	70	.	.	PUNCT
admet-162	21	1	because	because	SCONJ
admet-162	21	2	a	a	DET
admet-162	21	3	wide	wide	ADJ
admet-162	21	4	spectrum	spectrum	NOUN
admet-162	21	5	of	of	ADP
admet-162	21	6	different	different	ADJ
admet-162	21	7	forms	form	NOUN
admet-162	21	8	of	of	ADP
admet-162	21	9	brain	brain	NOUN
admet-162	21	10	injuries	injury	NOUN
admet-162	21	11	can	can	AUX
admet-162	21	12	lead	lead	VERB
admet-162	21	13	in	in	ADP
admet-162	21	14	a	a	DET
admet-162	21	15	secondary	secondary	ADJ
admet-162	21	16	epileptic	epileptic	ADJ
admet-162	21	17	syndrome	syndrome	NOUN
admet-162	21	18	,	,	PUNCT
admet-162	21	19	it	it	PRON
admet-162	21	20	is	be	AUX
admet-162	21	21	important	important	ADJ
admet-162	21	22	to	to	PART
admet-162	21	23	add	add	VERB
admet-162	21	24	that	that	SCONJ
admet-162	21	25	the	the	DET
admet-162	21	26	presence	presence	NOUN
admet-162	21	27	of	of	ADP
admet-162	21	28	background	background	NOUN
admet-162	21	29	genes	gene	NOUN
admet-162	21	30	,	,	PUNCT
admet-162	21	31	developmentally	developmentally	ADV
admet-162	21	32	regulated	regulated	ADJ
admet-162	21	33	genes	gene	NOUN
admet-162	21	34	and/or	and/or	CCONJ
admet-162	21	35	epigenetic	epigenetic	ADJ
admet-162	21	36	factors	factor	NOUN
admet-162	21	37	,	,	PUNCT
admet-162	21	38	can	can	AUX
admet-162	21	39	play	play	VERB
admet-162	21	40	a	a	DET
admet-162	21	41	role	role	NOUN
admet-162	21	42	in	in	ADP
admet-162	21	43	these	these	DET
admet-162	21	44	process	process	NOUN
admet-162	21	45	.	.	PUNCT
admet-162	22	1	perhaps	perhaps	ADV
admet-162	22	2	,	,	PUNCT
admet-162	22	3	stroke	stroke	NOUN
admet-162	22	4	,	,	PUNCT
admet-162	22	5	brain	brain	NOUN
admet-162	22	6	hypoxia	hypoxia	NOUN
admet-162	22	7	and/or	and/or	CCONJ
admet-162	22	8	status	status	NOUN
admet-162	22	9	epilepticus	epilepticus	NOUN
admet-162	22	10	are	be	AUX
admet-162	22	11	the	the	DET
admet-162	22	12	more	more	ADV
admet-162	22	13	clear	clear	ADJ
admet-162	22	14	conditions	condition	NOUN
admet-162	22	15	that	that	PRON
admet-162	22	16	can	can	AUX
admet-162	22	17	develop	develop	VERB
admet-162	22	18	secondary	secondary	ADJ
admet-162	22	19	epilepsy	epilepsy	NOUN
admet-162	22	20	as	as	ADV
admet-162	22	21	well	well	ADV
admet-162	22	22	as	as	ADP
admet-162	22	23	to	to	PART
admet-162	22	24	disclose	disclose	VERB
admet-162	22	25	a	a	DET
admet-162	22	26	refractory	refractory	NOUN
admet-162	22	27	phenotype	phenotype	NOUN
admet-162	23	1	[	[	X
admet-162	23	2	5	5	NUM
admet-162	23	3	]	]	PUNCT
admet-162	23	4	.	.	PUNCT
admet-162	24	1	neuronal	neuronal	ADJ
admet-162	24	2	excitability	excitability	NOUN
admet-162	24	3	can	can	AUX
admet-162	24	4	arise	arise	VERB
admet-162	24	5	from	from	ADP
admet-162	24	6	structural	structural	ADJ
admet-162	24	7	/	/	SYM
admet-162	24	8	functional	functional	ADJ
admet-162	24	9	changes	change	NOUN
admet-162	24	10	at	at	ADP
admet-162	24	11	the	the	DET
admet-162	24	12	postsynaptic	postsynaptic	ADJ
admet-162	24	13	membrane	membrane	NOUN
admet-162	24	14	level	level	NOUN
admet-162	24	15	,	,	PUNCT
admet-162	24	16	alterations	alteration	NOUN
admet-162	24	17	in	in	ADP
admet-162	24	18	the	the	DET
admet-162	24	19	type	type	NOUN
admet-162	24	20	,	,	PUNCT
admet-162	24	21	number	number	NOUN
admet-162	24	22	,	,	PUNCT
admet-162	24	23	and	and	CCONJ
admet-162	24	24	distribution	distribution	NOUN
admet-162	24	25	of	of	ADP
admet-162	24	26	voltageand	voltageand	NOUN
admet-162	24	27	ligand	ligand	NOUN
admet-162	24	28	-	-	PUNCT
admet-162	24	29	gated	gate	VERB
admet-162	24	30	ion	ion	NOUN
admet-162	24	31	channels	channel	NOUN
admet-162	24	32	or	or	CCONJ
admet-162	24	33	biochemical	biochemical	ADJ
admet-162	24	34	modification	modification	NOUN
admet-162	24	35	of	of	ADP
admet-162	24	36	receptors	receptor	NOUN
admet-162	24	37	that	that	PRON
admet-162	24	38	increase	increase	VERB
admet-162	24	39	permeability	permeability	NOUN
admet-162	24	40	to	to	ADP
admet-162	24	41	ca2	ca2	PROPN
admet-162	24	42	+	+	PROPN
admet-162	24	43	,	,	PUNCT
admet-162	24	44	favoring	favor	VERB
admet-162	24	45	development	development	NOUN
admet-162	24	46	of	of	ADP
admet-162	24	47	the	the	DET
admet-162	24	48	prolonged	prolonged	ADJ
admet-162	24	49	depolarization	depolarization	NOUN
admet-162	24	50	that	that	PRON
admet-162	24	51	precedes	precede	VERB
admet-162	24	52	seizures	seizure	NOUN
admet-162	24	53	.	.	PUNCT
admet-162	25	1	excessive	excessive	ADJ
admet-162	25	2	excitation	excitation	NOUN
admet-162	25	3	is	be	AUX
admet-162	25	4	the	the	DET
admet-162	25	5	key	key	ADJ
admet-162	25	6	factor	factor	NOUN
admet-162	25	7	underlying	underlie	VERB
admet-162	25	8	ictogenesis	ictogenesis	NOUN
admet-162	25	9	,	,	PUNCT
admet-162	25	10	which	which	PRON
admet-162	25	11	may	may	AUX
admet-162	25	12	originate	originate	VERB
admet-162	25	13	from	from	ADP
admet-162	25	14	individual	individual	ADJ
admet-162	25	15	neurons	neuron	NOUN
admet-162	25	16	,	,	PUNCT
admet-162	25	17	the	the	DET
admet-162	25	18	neuronal	neuronal	ADJ
admet-162	25	19	environment	environment	NOUN
admet-162	25	20	,	,	PUNCT
admet-162	25	21	or	or	CCONJ
admet-162	25	22	neuronal	neuronal	ADJ
admet-162	25	23	networks	network	NOUN
admet-162	25	24	[	[	X
admet-162	25	25	6	6	NUM
admet-162	25	26	]	]	PUNCT
admet-162	25	27	.	.	PUNCT
admet-162	26	1	the	the	DET
admet-162	26	2	imbalance	imbalance	NOUN
admet-162	26	3	between	between	ADP
admet-162	26	4	the	the	DET
admet-162	26	5	excitatory	excitatory	NOUN
admet-162	26	6	(	(	PUNCT
admet-162	26	7	high	high	ADJ
admet-162	26	8	)	)	PUNCT
admet-162	26	9	and	and	CCONJ
admet-162	26	10	the	the	DET
admet-162	26	11	inhibitory	inhibitory	NOUN
admet-162	26	12	(	(	PUNCT
admet-162	26	13	reduced	reduce	VERB
admet-162	26	14	)	)	PUNCT
admet-162	26	15	stimuli	stimulus	NOUN
admet-162	26	16	are	be	AUX
admet-162	26	17	the	the	DET
admet-162	26	18	main	main	ADJ
admet-162	26	19	mechanism	mechanism	NOUN
admet-162	26	20	of	of	ADP
admet-162	26	21	neuronal	neuronal	ADJ
admet-162	26	22	membrane	membrane	NOUN
admet-162	26	23	depolarization	depolarization	NOUN
admet-162	26	24	and	and	CCONJ
admet-162	26	25	the	the	DET
admet-162	26	26	onset	onset	NOUN
admet-162	26	27	of	of	ADP
admet-162	26	28	seizures	seizure	NOUN
admet-162	26	29	.	.	PUNCT
admet-162	27	1	neuronal	neuronal	ADJ
admet-162	27	2	axons	axon	NOUN
admet-162	27	3	have	have	VERB
admet-162	27	4	a	a	DET
admet-162	27	5	resting	rest	VERB
admet-162	27	6	membrane	membrane	NOUN
admet-162	27	7	potential	potential	NOUN
admet-162	27	8	of	of	ADP
admet-162	27	9	about	about	ADP
admet-162	27	10	-70	-70	PROPN
admet-162	27	11	mv	mv	PROPN
admet-162	27	12	inside	inside	ADP
admet-162	27	13	vs	vs	ADP
admet-162	27	14	outside	outside	NOUN
admet-162	27	15	.	.	PUNCT
admet-162	28	1	action	action	NOUN
admet-162	28	2	potentials	potential	NOUN
admet-162	28	3	occur	occur	VERB
admet-162	28	4	due	due	ADJ
admet-162	28	5	to	to	ADP
admet-162	28	6	net	net	ADJ
admet-162	28	7	positive	positive	ADJ
admet-162	28	8	inward	inward	ADJ
admet-162	28	9	ion	ion	NOUN
admet-162	28	10	fluxes	flux	NOUN
admet-162	28	11	,	,	PUNCT
admet-162	28	12	resulting	result	VERB
admet-162	28	13	in	in	ADP
admet-162	28	14	local	local	ADJ
admet-162	28	15	changes	change	NOUN
admet-162	28	16	in	in	ADP
admet-162	28	17	the	the	DET
admet-162	28	18	membrane	membrane	NOUN
admet-162	28	19	potential	potential	NOUN
admet-162	28	20	.	.	PUNCT
admet-162	29	1	membrane	membrane	NOUN
admet-162	29	2	potentials	potential	NOUN
admet-162	29	3	vary	vary	VERB
admet-162	29	4	with	with	ADP
admet-162	29	5	the	the	DET
admet-162	29	6	activation	activation	NOUN
admet-162	29	7	of	of	ADP
admet-162	29	8	either	either	CCONJ
admet-162	29	9	ligandor	ligandor	PROPN
admet-162	29	10	voltage	voltage	NOUN
admet-162	29	11	-	-	PUNCT
admet-162	29	12	gated	gate	VERB
admet-162	29	13	ion	ion	NOUN
admet-162	29	14	channels	channel	NOUN
admet-162	29	15	,	,	PUNCT
admet-162	29	16	which	which	PRON
admet-162	29	17	are	be	AUX
admet-162	29	18	affected	affect	VERB
admet-162	29	19	by	by	ADP
admet-162	29	20	changes	change	NOUN
admet-162	29	21	in	in	ADP
admet-162	29	22	either	either	CCONJ
admet-162	29	23	the	the	DET
admet-162	29	24	membrane	membrane	NOUN
admet-162	29	25	potential	potential	NOUN
admet-162	29	26	or	or	CCONJ
admet-162	29	27	intracellular	intracellular	ADJ
admet-162	29	28	ion	ion	NOUN
admet-162	29	29	concentration	concentration	NOUN
admet-162	29	30	.	.	PUNCT
admet-162	30	1	when	when	SCONJ
admet-162	30	2	a	a	DET
admet-162	30	3	neuron	neuron	NOUN
admet-162	30	4	is	be	AUX
admet-162	30	5	at	at	ADP
admet-162	30	6	-70	-70	PROPN
admet-162	30	7	mv	mv	PROPN
admet-162	30	8	it	it	PRON
admet-162	30	9	is	be	AUX
admet-162	30	10	said	say	VERB
admet-162	30	11	to	to	PART
admet-162	30	12	be	be	AUX
admet-162	30	13	at	at	ADP
admet-162	30	14	resting	rest	VERB
admet-162	30	15	potential	potential	NOUN
admet-162	30	16	.	.	PUNCT
admet-162	31	1	here	here	ADV
admet-162	31	2	,	,	PUNCT
admet-162	31	3	a	a	DET
admet-162	31	4	neuron	neuron	NOUN
admet-162	31	5	is	be	AUX
admet-162	31	6	not	not	PART
admet-162	31	7	being	be	AUX
admet-162	31	8	excited	excite	VERB
admet-162	31	9	by	by	ADP
admet-162	31	10	anything	anything	PRON
admet-162	31	11	and	and	CCONJ
admet-162	31	12	is	be	AUX
admet-162	31	13	basically	basically	ADV
admet-162	31	14	asleep	asleep	ADJ
admet-162	31	15	,	,	PUNCT
admet-162	31	16	awaiting	await	VERB
admet-162	31	17	input	input	NOUN
admet-162	31	18	from	from	ADP
admet-162	31	19	other	other	ADJ
admet-162	31	20	neurons	neuron	NOUN
admet-162	31	21	.	.	PUNCT
admet-162	32	1	resting	rest	VERB
admet-162	32	2	potential	potential	NOUN
admet-162	32	3	is	be	AUX
admet-162	32	4	maintained	maintain	VERB
admet-162	32	5	by	by	ADP
admet-162	32	6	the	the	DET
admet-162	32	7	sodiumpotassium	sodiumpotassium	ADJ
admet-162	32	8	pump	pump	NOUN
admet-162	32	9	,	,	PUNCT
admet-162	32	10	which	which	PRON
admet-162	32	11	constantly	constantly	ADV
admet-162	32	12	pushes	push	VERB
admet-162	32	13	sodium	sodium	NOUN
admet-162	32	14	out	out	ADP
admet-162	32	15	of	of	ADP
admet-162	32	16	the	the	DET
admet-162	32	17	neuron	neuron	NOUN
admet-162	32	18	.	.	PUNCT
admet-162	33	1	the	the	DET
admet-162	33	2	pump	pump	NOUN
admet-162	33	3	operates	operate	VERB
admet-162	33	4	via	via	ADP
admet-162	33	5	a	a	DET
admet-162	33	6	bunch	bunch	NOUN
admet-162	33	7	of	of	ADP
admet-162	33	8	sodium	sodium	NOUN
admet-162	33	9	-	-	PUNCT
admet-162	33	10	potassium	potassium	NOUN
admet-162	33	11	transporters	transporter	NOUN
admet-162	33	12	located	locate	VERB
admet-162	33	13	along	along	ADP
admet-162	33	14	the	the	DET
admet-162	33	15	membrane	membrane	NOUN
admet-162	33	16	.	.	PUNCT
admet-162	34	1	these	these	DET
admet-162	34	2	transporters	transporter	NOUN
admet-162	34	3	push	push	VERB
admet-162	34	4	three	three	NUM
admet-162	34	5	sodium	sodium	NOUN
admet-162	34	6	molecules	molecule	NOUN
admet-162	34	7	out	out	ADP
admet-162	34	8	for	for	ADP
admet-162	34	9	every	every	DET
admet-162	34	10	two	two	NUM
admet-162	34	11	potassium	potassium	NOUN
admet-162	34	12	molecules	molecule	NOUN
admet-162	34	13	it	it	PRON
admet-162	34	14	takes	take	VERB
admet-162	34	15	in	in	ADP
admet-162	34	16	.	.	PUNCT
admet-162	35	1	resting	rest	VERB
admet-162	35	2	potential	potential	ADJ
admet-162	35	3	exists	exist	NOUN
admet-162	35	4	when	when	SCONJ
admet-162	35	5	sodium	sodium	NOUN
admet-162	35	6	is	be	AUX
admet-162	35	7	on	on	ADP
admet-162	35	8	the	the	DET
admet-162	35	9	outside	outside	NOUN
admet-162	35	10	of	of	ADP
admet-162	35	11	the	the	DET
admet-162	35	12	cell	cell	NOUN
admet-162	35	13	and	and	CCONJ
admet-162	35	14	potassium	potassium	NOUN
admet-162	35	15	is	be	AUX
admet-162	35	16	on	on	ADP
admet-162	35	17	the	the	DET
admet-162	35	18	inside	inside	NOUN
admet-162	35	19	.	.	PUNCT
admet-162	36	1	when	when	SCONJ
admet-162	36	2	a	a	DET
admet-162	36	3	neuron	neuron	NOUN
admet-162	36	4	is	be	AUX
admet-162	36	5	excited	excite	VERB
admet-162	36	6	the	the	DET
admet-162	36	7	membrane	membrane	ADJ
admet-162	36	8	potential	potential	ADJ
admet-162	36	9	shoots	shoot	NOUN
admet-162	36	10	from	from	ADP
admet-162	36	11	-70	-70	PROPN
admet-162	36	12	mv	mv	PROPN
admet-162	36	13	to	to	ADP
admet-162	36	14	about	about	ADV
admet-162	36	15	40	40	NUM
admet-162	36	16	mv	mv	NOUN
admet-162	36	17	and	and	CCONJ
admet-162	36	18	the	the	DET
admet-162	36	19	membrane	membrane	NOUN
admet-162	36	20	is	be	AUX
admet-162	36	21	depolarized	depolarize	VERB
admet-162	36	22	.	.	PUNCT
admet-162	37	1	the	the	DET
admet-162	37	2	excitability	excitability	NOUN
admet-162	37	3	of	of	ADP
admet-162	37	4	synaptic	synaptic	ADJ
admet-162	37	5	terminals	terminal	NOUN
admet-162	37	6	depends	depend	VERB
admet-162	37	7	on	on	ADP
admet-162	37	8	the	the	DET
admet-162	37	9	amount	amount	NOUN
admet-162	37	10	of	of	ADP
admet-162	37	11	excitatory	excitatory	NOUN
admet-162	37	12	neurotransmitter	neurotransmitter	NOUN
admet-162	37	13	released	release	VERB
admet-162	37	14	(	(	PUNCT
admet-162	37	15	e.g.	e.g.	ADV
admet-162	37	16	,	,	PUNCT
admet-162	37	17	glutamic	glutamic	ADJ
admet-162	37	18	acid	acid	NOUN
admet-162	37	19	or	or	CCONJ
admet-162	37	20	activation	activation	NOUN
admet-162	37	21	of	of	ADP
admet-162	37	22	glutamergic	glutamergic	NOUN
admet-162	37	23	receptors	receptor	NOUN
admet-162	37	24	)	)	PUNCT
admet-162	37	25	as	as	ADV
admet-162	37	26	well	well	ADV
admet-162	37	27	as	as	ADP
admet-162	37	28	of	of	ADP
admet-162	37	29	an	an	DET
admet-162	37	30	insufficient	insufficient	ADJ
admet-162	37	31	amount	amount	NOUN
admet-162	37	32	of	of	ADP
admet-162	37	33	inhibitor	inhibitor	NOUN
admet-162	37	34	neurotransmitter	neurotransmitter	NOUN
admet-162	37	35	released	release	VERB
admet-162	37	36	(	(	PUNCT
admet-162	37	37	e.g.	e.g.	ADV
admet-162	37	38	,	,	PUNCT
admet-162	37	39	γ	γ	NOUN
admet-162	37	40	-	-	ADJ
admet-162	37	41	aminobutyric	aminobutyric	ADJ
admet-162	37	42	acid	acid	NOUN
admet-162	37	43	,	,	PUNCT
admet-162	37	44	or	or	CCONJ
admet-162	37	45	gaba	gaba	NOUN
admet-162	37	46	)	)	PUNCT
admet-162	37	47	,	,	PUNCT
admet-162	37	48	and	and	CCONJ
admet-162	37	49	consequently	consequently	ADV
admet-162	37	50	of	of	ADP
admet-162	37	51	the	the	DET
admet-162	37	52	final	final	ADJ
admet-162	37	53	extent	extent	NOUN
admet-162	37	54	of	of	ADP
admet-162	37	55	membrane	membrane	NOUN
admet-162	37	56	depolarization	depolarization	NOUN
admet-162	37	57	produced	produce	VERB
admet-162	37	58	.	.	PUNCT
admet-162	38	1	interestingly	interestingly	ADV
admet-162	38	2	,	,	PUNCT
admet-162	38	3	through	through	ADP
admet-162	38	4	the	the	DET
admet-162	38	5	axis	axis	NOUN
admet-162	38	6	glutamate	glutamate	NOUN
admet-162	38	7	/	/	SYM
admet-162	38	8	nmda	nmda	ADJ
admet-162	38	9	receptor	receptor	NOUN
admet-162	38	10	/	/	SYM
admet-162	38	11	cyclooxygenase-2	cyclooxygenase-2	NUM
admet-162	38	12	(	(	PUNCT
admet-162	38	13	cox-2	cox-2	NOUN
admet-162	38	14	)	)	PUNCT
admet-162	38	15	signaling	signal	VERB
admet-162	38	16	,	,	PUNCT
admet-162	38	17	glutamate	glutamate	NOUN
admet-162	38	18	can	can	AUX
admet-162	38	19	induces	induce	VERB
admet-162	38	20	overexpression	overexpression	NOUN
admet-162	38	21	of	of	ADP
admet-162	38	22	p	p	NOUN
admet-162	38	23	-	-	PUNCT
admet-162	38	24	glycoprotein	glycoprotein	NOUN
admet-162	38	25	(	(	PUNCT
admet-162	38	26	p	p	NOUN
admet-162	38	27	-	-	PUNCT
admet-162	38	28	gp	gp	NOUN
admet-162	38	29	)	)	PUNCT
admet-162	38	30	in	in	ADP
admet-162	38	31	brain	brain	NOUN
admet-162	38	32	[	[	X
admet-162	38	33	7,8	7,8	NUM
admet-162	38	34	]	]	PUNCT
admet-162	38	35	.	.	PUNCT
admet-162	39	1	the	the	DET
admet-162	39	2	efflux	efflux	NOUN
admet-162	39	3	of	of	ADP
admet-162	39	4	drugs	drug	NOUN
admet-162	39	5	by	by	ADP
admet-162	39	6	the	the	DET
admet-162	39	7	multidrug	multidrug	NOUN
admet-162	39	8	transporters	transporter	NOUN
admet-162	39	9	,	,	PUNCT
admet-162	39	10	particularly	particularly	ADV
admet-162	39	11	p	p	NOUN
admet-162	39	12	-	-	PUNCT
admet-162	39	13	gp	gp	NOUN
admet-162	39	14	lazarowski	lazarowski	NOUN
admet-162	39	15	et	et	PROPN
admet-162	39	16	al	al	PROPN
admet-162	39	17	.	.	PROPN
admet-162	39	18	admet	admet	PROPN
admet-162	39	19	&	&	CCONJ
admet-162	39	20	dmpk	dmpk	PROPN
admet-162	39	21	3(2	3(2	NUM
admet-162	39	22	)	)	PUNCT
admet-162	39	23	(	(	PUNCT
admet-162	39	24	2015	2015	NUM
admet-162	39	25	)	)	PUNCT
admet-162	39	26	110	110	NUM
admet-162	39	27	-	-	SYM
admet-162	39	28	121	121	NUM
admet-162	39	29	112	112	NUM
admet-162	39	30	(	(	PUNCT
admet-162	39	31	abcb1	abcb1	NOUN
admet-162	39	32	-	-	PUNCT
admet-162	39	33	transporter	transporter	NOUN
admet-162	39	34	)	)	PUNCT
admet-162	39	35	is	be	AUX
admet-162	39	36	one	one	NUM
admet-162	39	37	of	of	ADP
admet-162	39	38	the	the	DET
admet-162	39	39	principal	principal	NOUN
admet-162	39	40	means	mean	NOUN
admet-162	39	41	by	by	ADP
admet-162	39	42	which	which	PRON
admet-162	39	43	several	several	ADJ
admet-162	39	44	patients	patient	NOUN
admet-162	39	45	with	with	ADP
admet-162	39	46	pharmacoresistant	pharmacoresistant	ADJ
admet-162	39	47	epilepsy	epilepsy	NOUN
admet-162	39	48	develops	develop	VERB
admet-162	39	49	refractoriness	refractoriness	NOUN
admet-162	39	50	to	to	ADP
admet-162	39	51	a	a	DET
admet-162	39	52	wide	wide	ADJ
admet-162	39	53	spectrum	spectrum	NOUN
admet-162	39	54	of	of	ADP
admet-162	39	55	antiepileptic	antiepileptic	ADJ
admet-162	39	56	drugs	drug	NOUN
admet-162	39	57	(	(	PUNCT
admet-162	39	58	aeds	aed	NOUN
admet-162	39	59	)	)	PUNCT
admet-162	40	1	[	[	X
admet-162	40	2	9,10	9,10	NUM
admet-162	40	3	]	]	X
admet-162	40	4	.	.	PUNCT
admet-162	41	1	the	the	DET
admet-162	41	2	questions	question	NOUN
admet-162	41	3	are	be	AUX
admet-162	41	4	how	how	SCONJ
admet-162	41	5	so	so	ADV
admet-162	41	6	different	different	ADJ
admet-162	41	7	factors	factor	NOUN
admet-162	41	8	and	and	CCONJ
admet-162	41	9	cellular	cellular	ADJ
admet-162	41	10	/	/	SYM
admet-162	41	11	molecular	molecular	ADJ
admet-162	41	12	process	process	NOUN
admet-162	41	13	underlying	underlie	VERB
admet-162	41	14	during	during	ADP
admet-162	41	15	brain	brain	NOUN
admet-162	41	16	injury	injury	NOUN
admet-162	41	17	,	,	PUNCT
admet-162	41	18	can	can	AUX
admet-162	41	19	induce	induce	VERB
admet-162	41	20	an	an	DET
admet-162	41	21	enduring	endure	VERB
admet-162	41	22	phenomenon	phenomenon	NOUN
admet-162	41	23	with	with	ADP
admet-162	41	24	chronically	chronically	ADV
admet-162	41	25	recurrent	recurrent	ADJ
admet-162	41	26	seizures	seizure	NOUN
admet-162	41	27	and	and	CCONJ
admet-162	41	28	why	why	SCONJ
admet-162	41	29	persistent	persistent	ADJ
admet-162	41	30	(	(	PUNCT
admet-162	41	31	without	without	ADP
admet-162	41	32	control	control	NOUN
admet-162	41	33	)	)	PUNCT
admet-162	41	34	convulsive	convulsive	ADJ
admet-162	41	35	stress	stress	NOUN
admet-162	41	36	is	be	AUX
admet-162	41	37	a	a	DET
admet-162	41	38	main	main	ADJ
admet-162	41	39	risk	risk	NOUN
admet-162	41	40	factor	factor	NOUN
admet-162	41	41	of	of	AUX
admet-162	41	42	develop	develop	VERB
admet-162	41	43	pharmacoresistant	pharmacoresistant	ADJ
admet-162	41	44	epilepsy	epilepsy	NOUN
admet-162	41	45	?	?	PUNCT
admet-162	42	1	so	so	ADV
admet-162	42	2	,	,	PUNCT
admet-162	42	3	is	be	AUX
admet-162	42	4	the	the	DET
admet-162	42	5	acquired	acquire	VERB
admet-162	42	6	refractoriness	refractoriness	NOUN
admet-162	42	7	an	an	DET
admet-162	42	8	inducible	inducible	ADJ
admet-162	42	9	process	process	NOUN
admet-162	42	10	?	?	PUNCT
admet-162	43	1	abc	abc	PROPN
admet-162	43	2	-	-	PUNCT
admet-162	43	3	transporters	transporter	NOUN
admet-162	43	4	:	:	PUNCT
admet-162	43	5	p	p	X
admet-162	43	6	-	-	PUNCT
admet-162	43	7	glycoprotein	glycoprotein	NOUN
admet-162	43	8	the	the	DET
admet-162	43	9	movement	movement	NOUN
admet-162	43	10	of	of	ADP
admet-162	43	11	different	different	ADJ
admet-162	43	12	compounds	compound	NOUN
admet-162	43	13	as	as	ADP
admet-162	43	14	solutes	solute	NOUN
admet-162	43	15	,	,	PUNCT
admet-162	43	16	nutrients	nutrient	NOUN
admet-162	43	17	,	,	PUNCT
admet-162	43	18	ions	ion	NOUN
admet-162	43	19	,	,	PUNCT
admet-162	43	20	toxics	toxic	NOUN
admet-162	43	21	or	or	CCONJ
admet-162	43	22	drugs	drug	NOUN
admet-162	43	23	across	across	ADP
admet-162	43	24	cell	cell	NOUN
admet-162	43	25	membranes	membrane	NOUN
admet-162	43	26	is	be	AUX
admet-162	43	27	a	a	DET
admet-162	43	28	critical	critical	ADJ
admet-162	43	29	biological	biological	ADJ
admet-162	43	30	process	process	NOUN
admet-162	43	31	where	where	SCONJ
admet-162	43	32	the	the	DET
admet-162	43	33	atp	atp	NOUN
admet-162	43	34	-	-	PUNCT
admet-162	43	35	binding	bind	VERB
admet-162	43	36	cassette	cassette	NOUN
admet-162	43	37	(	(	PUNCT
admet-162	43	38	abc	abc	PROPN
admet-162	43	39	)	)	PUNCT
admet-162	43	40	transporter´s	transporter´s	NOUN
admet-162	43	41	family	family	NOUN
admet-162	43	42	plays	play	VERB
admet-162	43	43	a	a	DET
admet-162	43	44	central	central	ADJ
admet-162	43	45	role	role	NOUN
admet-162	43	46	and	and	CCONJ
admet-162	43	47	represents	represent	VERB
admet-162	43	48	one	one	NUM
admet-162	43	49	of	of	ADP
admet-162	43	50	the	the	DET
admet-162	43	51	largest	large	ADJ
admet-162	43	52	families	family	NOUN
admet-162	43	53	of	of	ADP
admet-162	43	54	transport	transport	NOUN
admet-162	43	55	proteins	protein	NOUN
admet-162	43	56	[	[	X
admet-162	43	57	11	11	NUM
admet-162	43	58	-	-	SYM
admet-162	43	59	13	13	NUM
admet-162	43	60	]	]	PUNCT
admet-162	43	61	.	.	PUNCT
admet-162	44	1	several	several	ADJ
admet-162	44	2	functional	functional	ADJ
admet-162	44	3	properties	property	NOUN
admet-162	44	4	of	of	ADP
admet-162	44	5	these	these	DET
admet-162	44	6	transporters	transporter	NOUN
admet-162	44	7	have	have	AUX
admet-162	44	8	been	be	AUX
admet-162	44	9	described	describe	VERB
admet-162	44	10	and	and	CCONJ
admet-162	44	11	their	their	PRON
admet-162	44	12	importance	importance	NOUN
admet-162	44	13	is	be	AUX
admet-162	44	14	indicated	indicate	VERB
admet-162	44	15	not	not	PART
admet-162	44	16	only	only	ADV
admet-162	44	17	by	by	ADP
admet-162	44	18	the	the	DET
admet-162	44	19	large	large	ADJ
admet-162	44	20	number	number	NOUN
admet-162	44	21	of	of	ADP
admet-162	44	22	encoding	encoding	NOUN
admet-162	44	23	genes	gene	NOUN
admet-162	44	24	,	,	PUNCT
admet-162	44	25	or	or	CCONJ
admet-162	44	26	their	their	PRON
admet-162	44	27	ubiquitous	ubiquitous	ADJ
admet-162	44	28	expression	expression	NOUN
admet-162	44	29	,	,	PUNCT
admet-162	44	30	but	but	CCONJ
admet-162	44	31	also	also	ADV
admet-162	44	32	by	by	ADP
admet-162	44	33	their	their	PRON
admet-162	44	34	ancestral	ancestral	ADJ
admet-162	44	35	origin	origin	NOUN
admet-162	44	36	and	and	CCONJ
admet-162	44	37	because	because	SCONJ
admet-162	44	38	22	22	NUM
admet-162	44	39	of	of	ADP
admet-162	44	40	48	48	NUM
admet-162	44	41	human	human	ADJ
admet-162	44	42	abc	abc	PROPN
admet-162	44	43	proteins	protein	NOUN
admet-162	44	44	are	be	AUX
admet-162	44	45	implicated	implicate	VERB
admet-162	44	46	in	in	ADP
admet-162	44	47	human	human	ADJ
admet-162	44	48	diseases	disease	NOUN
admet-162	44	49	[	[	X
admet-162	44	50	14	14	NUM
admet-162	44	51	]	]	PUNCT
admet-162	44	52	.	.	PUNCT
admet-162	45	1	the	the	DET
admet-162	45	2	presence	presence	NOUN
admet-162	45	3	of	of	ADP
admet-162	45	4	these	these	DET
admet-162	45	5	pumps	pump	NOUN
admet-162	45	6	in	in	ADP
admet-162	45	7	the	the	DET
admet-162	45	8	liver	liver	NOUN
admet-162	45	9	,	,	PUNCT
admet-162	45	10	bowel	bowel	NOUN
admet-162	45	11	,	,	PUNCT
admet-162	45	12	and	and	CCONJ
admet-162	45	13	kidney	kidney	NOUN
admet-162	45	14	and	and	CCONJ
admet-162	45	15	bbb	bbb	PROPN
admet-162	45	16	suggests	suggest	VERB
admet-162	45	17	that	that	SCONJ
admet-162	45	18	these	these	DET
admet-162	45	19	transport	transport	NOUN
admet-162	45	20	systems	system	NOUN
admet-162	45	21	have	have	AUX
admet-162	45	22	evolved	evolve	VERB
admet-162	45	23	to	to	PART
admet-162	45	24	protect	protect	VERB
admet-162	45	25	the	the	DET
admet-162	45	26	organism	organism	NOUN
admet-162	45	27	against	against	ADP
admet-162	45	28	,	,	PUNCT
admet-162	45	29	endogenous	endogenous	ADJ
admet-162	45	30	/	/	SYM
admet-162	45	31	circulating	circulate	VERB
admet-162	45	32	chemicals	chemical	NOUN
admet-162	45	33	,	,	PUNCT
admet-162	45	34	xenobiotics	xenobiotic	NOUN
admet-162	45	35	,	,	PUNCT
admet-162	45	36	organic	organic	ADJ
admet-162	45	37	ions	ion	NOUN
admet-162	45	38	,	,	PUNCT
admet-162	45	39	and	and	CCONJ
admet-162	45	40	drugs	drug	NOUN
admet-162	45	41	[	[	X
admet-162	45	42	15	15	NUM
admet-162	45	43	]	]	PUNCT
admet-162	45	44	.	.	PUNCT
admet-162	46	1	particularly	particularly	ADV
admet-162	46	2	the	the	DET
admet-162	46	3	p	p	NOUN
admet-162	46	4	-	-	PUNCT
admet-162	46	5	gp	gp	NOUN
admet-162	46	6	was	be	AUX
admet-162	46	7	the	the	DET
admet-162	46	8	first	first	ADJ
admet-162	46	9	eukaryotic	eukaryotic	ADJ
admet-162	46	10	abc	abc	PROPN
admet-162	46	11	-	-	PUNCT
admet-162	46	12	transporter	transporter	NOUN
admet-162	46	13	identified	identify	VERB
admet-162	46	14	conferring	confer	VERB
admet-162	46	15	multidrug	multidrug	NOUN
admet-162	46	16	resistance	resistance	NOUN
admet-162	46	17	to	to	ADP
admet-162	46	18	cancer	cancer	NOUN
admet-162	46	19	cells	cell	NOUN
admet-162	46	20	[	[	X
admet-162	46	21	16,17	16,17	NUM
admet-162	46	22	]	]	PUNCT
admet-162	46	23	.	.	PUNCT
admet-162	47	1	p	p	X
admet-162	47	2	-	-	PUNCT
admet-162	47	3	gp	gp	NOUN
admet-162	47	4	has	have	VERB
admet-162	47	5	a	a	DET
admet-162	47	6	molecular	molecular	ADJ
admet-162	47	7	architecture	architecture	NOUN
admet-162	47	8	with	with	ADP
admet-162	47	9	a	a	DET
admet-162	47	10	core	core	NOUN
admet-162	47	11	structure	structure	NOUN
admet-162	47	12	of	of	ADP
admet-162	47	13	two	two	NUM
admet-162	47	14	pairs	pair	NOUN
admet-162	47	15	of	of	ADP
admet-162	47	16	domains	domain	NOUN
admet-162	47	17	of	of	ADP
admet-162	47	18	nucleotide	nucleotide	ADJ
admet-162	47	19	binding	bind	VERB
admet-162	47	20	domain	domain	NOUN
admet-162	47	21	(	(	PUNCT
admet-162	47	22	nbd	nbd	PROPN
admet-162	47	23	)	)	PUNCT
admet-162	47	24	where	where	SCONJ
admet-162	47	25	atp	atp	PROPN
admet-162	47	26	is	be	AUX
admet-162	47	27	hydrolyzed	hydrolyze	VERB
admet-162	47	28	and	and	CCONJ
admet-162	47	29	the	the	DET
admet-162	47	30	transmembrane	transmembrane	ADJ
admet-162	47	31	domain	domain	NOUN
admet-162	47	32	(	(	PUNCT
admet-162	47	33	tmd	tmd	NOUN
admet-162	47	34	)	)	PUNCT
admet-162	47	35	that	that	PRON
admet-162	47	36	consists	consist	VERB
admet-162	47	37	of	of	ADP
admet-162	47	38	six	six	NUM
admet-162	47	39	transmembrane	transmembrane	ADJ
admet-162	47	40	helices	helix	NOUN
admet-162	47	41	and	and	CCONJ
admet-162	47	42	where	where	SCONJ
admet-162	47	43	is	be	AUX
admet-162	47	44	the	the	DET
admet-162	47	45	drugbinding	drugbinde	VERB
admet-162	47	46	site	site	NOUN
admet-162	47	47	.	.	PUNCT
admet-162	48	1	the	the	DET
admet-162	48	2	mechanistic	mechanistic	ADJ
admet-162	48	3	way	way	NOUN
admet-162	48	4	of	of	ADP
admet-162	48	5	drugs	drug	NOUN
admet-162	48	6	transport	transport	NOUN
admet-162	48	7	is	be	AUX
admet-162	48	8	based	base	VERB
admet-162	48	9	on	on	ADP
admet-162	48	10	conformational	conformational	ADJ
admet-162	48	11	changes	change	NOUN
admet-162	48	12	at	at	ADP
admet-162	48	13	the	the	DET
admet-162	48	14	nbds	nbds	NOUN
admet-162	48	15	level	level	NOUN
admet-162	48	16	,	,	PUNCT
admet-162	48	17	transmitted	transmit	VERB
admet-162	48	18	to	to	ADP
admet-162	48	19	the	the	DET
admet-162	48	20	tmds	tmds	NOUN
admet-162	48	21	,	,	PUNCT
admet-162	48	22	and	and	CCONJ
admet-162	48	23	producing	produce	VERB
admet-162	48	24	the	the	DET
admet-162	48	25	drug	drug	NOUN
admet-162	48	26	export	export	NOUN
admet-162	48	27	that	that	PRON
admet-162	48	28	is	be	AUX
admet-162	48	29	energy	energy	NOUN
admet-162	48	30	atp	atp	NOUN
admet-162	48	31	-	-	PUNCT
admet-162	48	32	dependent	dependent	ADJ
admet-162	48	33	[	[	X
admet-162	48	34	18,19	18,19	NUM
admet-162	48	35	]	]	X
admet-162	48	36	.	.	PUNCT
admet-162	49	1	an	an	DET
admet-162	49	2	‘	'	PUNCT
admet-162	49	3	‘	'	PUNCT
admet-162	49	4	alternating	alternate	VERB
admet-162	49	5	catalysis	catalysis	NOUN
admet-162	49	6	model	model	NOUN
admet-162	49	7	’’	’'	PUNCT
admet-162	49	8	have	have	AUX
admet-162	49	9	been	be	AUX
admet-162	49	10	described	describe	VERB
admet-162	49	11	indicating	indicate	VERB
admet-162	49	12	that	that	SCONJ
admet-162	49	13	after	after	ADP
admet-162	49	14	atp	atp	NOUN
admet-162	49	15	hydrolysis	hydrolysis	NOUN
admet-162	49	16	,	,	PUNCT
admet-162	49	17	adp	adp	PROPN
admet-162	49	18	could	could	AUX
admet-162	49	19	be	be	AUX
admet-162	49	20	trapped	trap	VERB
admet-162	49	21	at	at	ADP
admet-162	49	22	one	one	NUM
admet-162	49	23	of	of	ADP
admet-162	49	24	two	two	NUM
admet-162	49	25	nbds	nbds	NOUN
admet-162	49	26	.	.	PUNCT
admet-162	50	1	normally	normally	ADV
admet-162	50	2	,	,	PUNCT
admet-162	50	3	in	in	ADP
admet-162	50	4	the	the	DET
admet-162	50	5	absence	absence	NOUN
admet-162	50	6	of	of	ADP
admet-162	50	7	nucleotide	nucleotide	NOUN
admet-162	50	8	(	(	PUNCT
admet-162	50	9	state	state	NOUN
admet-162	50	10	i	i	PROPN
admet-162	50	11	)	)	PUNCT
admet-162	50	12	,	,	PUNCT
admet-162	50	13	the	the	DET
admet-162	50	14	two	two	NUM
admet-162	50	15	opposing	opposing	ADJ
admet-162	50	16	domains	domain	NOUN
admet-162	50	17	of	of	ADP
admet-162	50	18	the	the	DET
admet-162	50	19	atp	atp	NOUN
admet-162	50	20	sites	site	NOUN
admet-162	50	21	are	be	AUX
admet-162	50	22	in	in	ADP
admet-162	50	23	the	the	DET
admet-162	50	24	‘	'	PUNCT
admet-162	50	25	‘	'	PUNCT
admet-162	50	26	open	open	ADJ
admet-162	50	27	’’	’'	PUNCT
admet-162	50	28	conformation	conformation	NOUN
admet-162	50	29	,	,	PUNCT
admet-162	50	30	and	and	CCONJ
admet-162	50	31	the	the	DET
admet-162	50	32	binding	binding	NOUN
admet-162	50	33	of	of	ADP
admet-162	50	34	two	two	NUM
admet-162	50	35	molecules	molecule	NOUN
admet-162	50	36	of	of	ADP
admet-162	50	37	atp	atp	PROPN
admet-162	50	38	results	result	NOUN
admet-162	50	39	in	in	ADP
admet-162	50	40	the	the	DET
admet-162	50	41	formation	formation	NOUN
admet-162	50	42	of	of	ADP
admet-162	50	43	the	the	DET
admet-162	50	44	nucleotide	nucleotide	ADJ
admet-162	50	45	sandwich	sandwich	NOUN
admet-162	50	46	(	(	PUNCT
admet-162	50	47	state	state	PROPN
admet-162	50	48	ii	ii	PROPN
admet-162	50	49	)	)	PUNCT
admet-162	50	50	that	that	PRON
admet-162	50	51	draws	draw	VERB
admet-162	50	52	together	together	ADV
admet-162	50	53	the	the	DET
admet-162	50	54	opposing	opposing	ADJ
admet-162	50	55	faces	face	NOUN
admet-162	50	56	of	of	ADP
admet-162	50	57	the	the	DET
admet-162	50	58	atp	atp	NOUN
admet-162	50	59	sites	site	NOUN
admet-162	50	60	.	.	PUNCT
admet-162	51	1	this	this	PRON
admet-162	51	2	is	be	AUX
admet-162	51	3	followed	follow	VERB
admet-162	51	4	by	by	ADP
admet-162	51	5	a	a	DET
admet-162	51	6	conformational	conformational	ADJ
admet-162	51	7	change	change	NOUN
admet-162	51	8	in	in	ADP
admet-162	51	9	which	which	PRON
admet-162	51	10	one	one	NUM
admet-162	51	11	of	of	ADP
admet-162	51	12	the	the	DET
admet-162	51	13	two	two	NUM
admet-162	51	14	atps	atps	NOUN
admet-162	51	15	is	be	AUX
admet-162	51	16	‘	'	PUNCT
admet-162	51	17	‘	'	PUNCT
admet-162	51	18	occluded	occlude	VERB
admet-162	51	19	’’	’'	PUNCT
admet-162	51	20	in	in	ADP
admet-162	51	21	a	a	DET
admet-162	51	22	non	non	ADJ
admet-162	51	23	-	-	ADJ
admet-162	51	24	exchangeable	exchangeable	ADJ
admet-162	51	25	form	form	NOUN
admet-162	51	26	(	(	PUNCT
admet-162	51	27	state	state	NOUN
admet-162	51	28	iii	iii	NOUN
admet-162	51	29	)	)	PUNCT
admet-162	51	30	(	(	PUNCT
admet-162	51	31	figure	figure	NOUN
admet-162	51	32	1)[20	1)[20	NUM
admet-162	51	33	]	]	PUNCT
admet-162	51	34	.	.	PUNCT
admet-162	52	1	abc	abc	PROPN
admet-162	52	2	-	-	PUNCT
admet-162	52	3	transporters	transporter	NOUN
admet-162	52	4	in	in	ADP
admet-162	52	5	the	the	DET
admet-162	52	6	brain	brain	NOUN
admet-162	52	7	the	the	DET
admet-162	52	8	central	central	ADJ
admet-162	52	9	nervous	nervous	ADJ
admet-162	52	10	system	system	NOUN
admet-162	52	11	(	(	PUNCT
admet-162	52	12	cns	cns	NOUN
admet-162	52	13	)	)	PUNCT
admet-162	52	14	effects	effect	NOUN
admet-162	52	15	of	of	ADP
admet-162	52	16	many	many	ADJ
admet-162	52	17	therapeutic	therapeutic	ADJ
admet-162	52	18	drugs	drug	NOUN
admet-162	52	19	are	be	AUX
admet-162	52	20	blunted	blunt	VERB
admet-162	52	21	because	because	SCONJ
admet-162	52	22	of	of	ADP
admet-162	52	23	restricted	restricted	ADJ
admet-162	52	24	entry	entry	NOUN
admet-162	52	25	into	into	ADP
admet-162	52	26	the	the	DET
admet-162	52	27	brain	brain	NOUN
admet-162	52	28	.	.	PUNCT
admet-162	53	1	the	the	DET
admet-162	53	2	basis	basis	NOUN
admet-162	53	3	for	for	ADP
admet-162	53	4	this	this	DET
admet-162	53	5	poor	poor	ADJ
admet-162	53	6	permeability	permeability	NOUN
admet-162	53	7	is	be	AUX
admet-162	53	8	the	the	DET
admet-162	53	9	brain	brain	NOUN
admet-162	53	10	capillary	capillary	ADJ
admet-162	53	11	endothelium	endothelium	NOUN
admet-162	53	12	,	,	PUNCT
admet-162	53	13	which	which	PRON
admet-162	53	14	comprises	comprise	VERB
admet-162	53	15	the	the	DET
admet-162	53	16	bbb	bbb	PROPN
admet-162	53	17	.	.	PUNCT
admet-162	54	1	this	this	DET
admet-162	54	2	tissue	tissue	NOUN
admet-162	54	3	exhibits	exhibit	VERB
admet-162	54	4	very	very	ADV
admet-162	54	5	low	low	ADV
admet-162	54	6	paracellular	paracellular	ADJ
admet-162	54	7	(	(	PUNCT
admet-162	54	8	tight	tight	ADJ
admet-162	54	9	junction	junction	NOUN
admet-162	54	10	,	,	PUNCT
admet-162	54	11	or	or	CCONJ
admet-162	54	12	tj	tj	NOUN
admet-162	54	13	)	)	PUNCT
admet-162	54	14	permeability	permeability	NOUN
admet-162	54	15	and	and	CCONJ
admet-162	54	16	expresses	express	VERB
admet-162	54	17	a	a	DET
admet-162	54	18	potent	potent	ADJ
admet-162	54	19	system	system	NOUN
admet-162	54	20	of	of	ADP
admet-162	54	21	drug	drug	NOUN
admet-162	54	22	export	export	NOUN
admet-162	54	23	pumps	pump	NOUN
admet-162	54	24	.	.	PUNCT
admet-162	55	1	the	the	DET
admet-162	55	2	bbb	bbb	PROPN
admet-162	55	3	is	be	AUX
admet-162	55	4	a	a	DET
admet-162	55	5	highly	highly	ADV
admet-162	55	6	specialized	specialized	ADJ
admet-162	55	7	structural	structural	ADJ
admet-162	55	8	and	and	CCONJ
admet-162	55	9	biochemical	biochemical	ADJ
admet-162	55	10	barrier	barrier	NOUN
admet-162	55	11	that	that	PRON
admet-162	55	12	regulates	regulate	VERB
admet-162	55	13	the	the	DET
admet-162	55	14	entry	entry	NOUN
admet-162	55	15	of	of	ADP
admet-162	55	16	blood	blood	NOUN
admet-162	55	17	-	-	PUNCT
admet-162	55	18	borne	bear	VERB
admet-162	55	19	molecules	molecule	NOUN
admet-162	55	20	and	and	CCONJ
admet-162	55	21	cells	cell	NOUN
admet-162	55	22	into	into	ADP
admet-162	55	23	the	the	DET
admet-162	55	24	brain	brain	NOUN
admet-162	55	25	and	and	CCONJ
admet-162	55	26	preserves	preserve	VERB
admet-162	55	27	ionic	ionic	ADJ
admet-162	55	28	homeostasis	homeostasis	NOUN
admet-162	55	29	within	within	ADP
admet-162	55	30	the	the	DET
admet-162	55	31	brain	brain	NOUN
admet-162	55	32	microenvironment	microenvironment	NOUN
admet-162	55	33	.	.	PUNCT
admet-162	56	1	admet	admet	PROPN
admet-162	56	2	&	&	CCONJ
admet-162	56	3	dmpk	dmpk	PROPN
admet-162	56	4	3(2	3(2	NUM
admet-162	56	5	)	)	PUNCT
admet-162	56	6	(	(	PUNCT
admet-162	56	7	2015	2015	NUM
admet-162	56	8	)	)	PUNCT
admet-162	56	9	110	110	NUM
admet-162	56	10	-	-	SYM
admet-162	56	11	121	121	NUM
admet-162	56	12	the	the	DET
admet-162	56	13	roles	role	NOUN
admet-162	56	14	of	of	ADP
admet-162	56	15	p	p	NOUN
admet-162	56	16	-	-	PUNCT
admet-162	56	17	gp	gp	NOUN
admet-162	56	18	in	in	ADP
admet-162	56	19	refractory	refractory	NOUN
admet-162	56	20	epilepsy	epilepsy	NOUN
admet-162	56	21	doi	doi	NOUN
admet-162	56	22	:	:	PUNCT
admet-162	56	23	10.5599	10.5599	NUM
admet-162	56	24	/	/	SYM
admet-162	56	25	admet.3.2.162	admet.3.2.162	ADP
admet-162	56	26	113	113	NUM
admet-162	56	27	figure	figure	NOUN
admet-162	56	28	1	1	NUM
admet-162	56	29	:	:	PUNCT
admet-162	56	30	drug	drug	NOUN
admet-162	56	31	efflux	efflux	NOUN
admet-162	56	32	cycle	cycle	NOUN
admet-162	56	33	:	:	PUNCT
admet-162	56	34	the	the	DET
admet-162	56	35	drug	drug	NOUN
admet-162	56	36	binds	bind	VERB
admet-162	56	37	first	first	ADV
admet-162	56	38	to	to	ADP
admet-162	56	39	the	the	DET
admet-162	56	40	tmd	tmd	NOUN
admet-162	56	41	producing	produce	VERB
admet-162	56	42	conformational	conformational	ADJ
admet-162	56	43	changes	change	NOUN
admet-162	56	44	of	of	ADP
admet-162	56	45	abc	abc	PROPN
admet-162	56	46	-	-	PUNCT
admet-162	56	47	transporter	transporter	NOUN
admet-162	56	48	.	.	PUNCT
admet-162	57	1	a	a	DET
admet-162	57	2	)	)	PUNCT
admet-162	57	3	state	state	NOUN
admet-162	57	4	i	i	NOUN
admet-162	57	5	:	:	PUNCT
admet-162	57	6	the	the	DET
admet-162	57	7	inactive	inactive	ADJ
admet-162	57	8	structure	structure	NOUN
admet-162	57	9	of	of	ADP
admet-162	57	10	p	p	NOUN
admet-162	57	11	-	-	PUNCT
admet-162	57	12	gp	gp	NOUN
admet-162	57	13	.	.	PUNCT
admet-162	58	1	b	b	X
admet-162	58	2	)	)	PUNCT
admet-162	58	3	state	state	PROPN
admet-162	58	4	ii	ii	PROPN
admet-162	58	5	:	:	PUNCT
admet-162	58	6	the	the	DET
admet-162	58	7	inward	inward	ADV
admet-162	58	8	-	-	PUNCT
admet-162	58	9	facing	face	VERB
admet-162	58	10	conformation	conformation	NOUN
admet-162	58	11	.	.	PUNCT
admet-162	59	1	c	c	X
admet-162	59	2	)	)	PUNCT
admet-162	59	3	state	state	NOUN
admet-162	59	4	iii	iii	PROPN
admet-162	59	5	:	:	PUNCT
admet-162	59	6	the	the	DET
admet-162	59	7	outward	outward	ADV
admet-162	59	8	-	-	PUNCT
admet-162	59	9	facing	face	VERB
admet-162	59	10	conformation	conformation	NOUN
admet-162	59	11	transporters	transporter	NOUN
admet-162	59	12	are	be	AUX
admet-162	59	13	abundantly	abundantly	ADV
admet-162	59	14	expressed	express	VERB
admet-162	59	15	in	in	ADP
admet-162	59	16	the	the	DET
admet-162	59	17	brain	brain	NOUN
admet-162	59	18	,	,	PUNCT
admet-162	59	19	mainly	mainly	ADV
admet-162	59	20	in	in	ADP
admet-162	59	21	the	the	DET
admet-162	59	22	vascular	vascular	ADJ
admet-162	59	23	endothelial	endothelial	NOUN
admet-162	59	24	cells	cell	NOUN
admet-162	59	25	(	(	PUNCT
admet-162	59	26	vec	vec	PROPN
admet-162	59	27	)	)	PUNCT
admet-162	59	28	of	of	ADP
admet-162	59	29	the	the	DET
admet-162	59	30	bbb	bbb	PROPN
admet-162	59	31	,	,	PUNCT
admet-162	59	32	the	the	DET
admet-162	59	33	epithelial	epithelial	ADJ
admet-162	59	34	cells	cell	NOUN
admet-162	59	35	of	of	ADP
admet-162	59	36	the	the	DET
admet-162	59	37	brain	brain	NOUN
admet-162	59	38	-	-	PUNCT
admet-162	59	39	cerebrospinal	cerebrospinal	ADJ
admet-162	59	40	fluid	fluid	NOUN
admet-162	59	41	barrier	barrier	NOUN
admet-162	59	42	(	(	PUNCT
admet-162	59	43	bcsfb	bcsfb	PROPN
admet-162	59	44	)	)	PUNCT
admet-162	59	45	,	,	PUNCT
admet-162	59	46	and	and	CCONJ
admet-162	59	47	also	also	ADV
admet-162	59	48	some	some	DET
admet-162	59	49	parenchyma	parenchyma	NOUN
admet-162	59	50	cells	cell	NOUN
admet-162	59	51	in	in	ADP
admet-162	59	52	brain	brain	NOUN
admet-162	59	53	,	,	PUNCT
admet-162	59	54	particularly	particularly	ADV
admet-162	59	55	in	in	ADP
admet-162	59	56	the	the	DET
admet-162	59	57	food	food	NOUN
admet-162	59	58	-	-	PUNCT
admet-162	59	59	ending	end	VERB
admet-162	59	60	process	process	NOUN
admet-162	59	61	of	of	ADP
admet-162	59	62	astrocytes	astrocyte	NOUN
admet-162	59	63	-	-	PUNCT
admet-162	59	64	touching	touch	VERB
admet-162	59	65	vec	vec	NOUN
admet-162	59	66	of	of	ADP
admet-162	59	67	vessels	vessel	NOUN
admet-162	59	68	.	.	PUNCT
admet-162	60	1	drug	drug	NOUN
admet-162	60	2	uptake	uptake	ADJ
admet-162	60	3	into	into	ADP
admet-162	60	4	the	the	DET
admet-162	60	5	brain	brain	NOUN
admet-162	60	6	highly	highly	ADV
admet-162	60	7	depends	depend	VERB
admet-162	60	8	on	on	ADP
admet-162	60	9	the	the	DET
admet-162	60	10	efflux	efflux	ADJ
admet-162	60	11	transporters	transporter	NOUN
admet-162	60	12	expressed	express	VERB
admet-162	60	13	at	at	ADP
admet-162	60	14	both	both	CCONJ
admet-162	60	15	bbb	bbb	NOUN
admet-162	60	16	and	and	CCONJ
admet-162	60	17	bcsfb	bcsfb	VERB
admet-162	60	18	biological	biological	ADJ
admet-162	60	19	barrier	barrier	NOUN
admet-162	60	20	systems	system	NOUN
admet-162	60	21	.	.	PUNCT
admet-162	61	1	a	a	DET
admet-162	61	2	polarized	polarize	VERB
admet-162	61	3	location	location	NOUN
admet-162	61	4	of	of	ADP
admet-162	61	5	the	the	DET
admet-162	61	6	drug	drug	NOUN
admet-162	61	7	efflux	efflux	NOUN
admet-162	61	8	transporters	transporter	NOUN
admet-162	61	9	is	be	AUX
admet-162	61	10	mainly	mainly	ADV
admet-162	61	11	present	present	ADJ
admet-162	61	12	on	on	ADP
admet-162	61	13	the	the	DET
admet-162	61	14	luminal	luminal	ADJ
admet-162	61	15	(	(	PUNCT
admet-162	61	16	apical	apical	ADJ
admet-162	61	17	or	or	CCONJ
admet-162	61	18	blood	blood	NOUN
admet-162	61	19	)	)	PUNCT
admet-162	61	20	side	side	NOUN
admet-162	61	21	of	of	ADP
admet-162	61	22	the	the	DET
admet-162	61	23	endothelial	endothelial	ADJ
admet-162	61	24	cells	cell	NOUN
admet-162	61	25	in	in	ADP
admet-162	61	26	the	the	DET
admet-162	61	27	brain	brain	NOUN
admet-162	61	28	capillary	capillary	ADJ
admet-162	61	29	where	where	SCONJ
admet-162	61	30	p	p	NOUN
admet-162	61	31	-	-	PUNCT
admet-162	61	32	gp	gp	NOUN
admet-162	61	33	,	,	PUNCT
admet-162	61	34	bcrp	bcrp	ADV
admet-162	61	35	,	,	PUNCT
admet-162	61	36	and	and	CCONJ
admet-162	61	37	mrp2	mrp2	PROPN
admet-162	61	38	are	be	AUX
admet-162	61	39	unequivocally	unequivocally	ADV
admet-162	61	40	expressed	express	VERB
admet-162	61	41	at	at	ADP
admet-162	61	42	the	the	DET
admet-162	61	43	blood	blood	NOUN
admet-162	61	44	side	side	NOUN
admet-162	61	45	.	.	PUNCT
admet-162	62	1	this	this	DET
admet-162	62	2	natural	natural	ADJ
admet-162	62	3	distribution	distribution	NOUN
admet-162	62	4	of	of	ADP
admet-162	62	5	the	the	DET
admet-162	62	6	main	main	ADJ
admet-162	62	7	drug	drug	NOUN
admet-162	62	8	-	-	PUNCT
admet-162	62	9	transporters	transporter	NOUN
admet-162	62	10	at	at	ADP
admet-162	62	11	bbb	bbb	PROPN
admet-162	62	12	,	,	PUNCT
admet-162	62	13	indicates	indicate	VERB
admet-162	62	14	that	that	SCONJ
admet-162	62	15	the	the	DET
admet-162	62	16	normal	normal	ADJ
admet-162	62	17	presence	presence	NOUN
admet-162	62	18	of	of	ADP
admet-162	62	19	some	some	DET
admet-162	62	20	abc	abc	NOUN
admet-162	62	21	-	-	PUNCT
admet-162	62	22	transporters	transporter	NOUN
admet-162	62	23	(	(	PUNCT
admet-162	62	24	including	include	VERB
admet-162	62	25	p	p	NOUN
admet-162	62	26	-	-	PUNCT
admet-162	62	27	gp	gp	NOUN
admet-162	62	28	)	)	PUNCT
admet-162	62	29	at	at	ADP
admet-162	62	30	bbb	bbb	PROPN
admet-162	62	31	level	level	NOUN
admet-162	62	32	,	,	PUNCT
admet-162	62	33	is	be	AUX
admet-162	62	34	not	not	PART
admet-162	62	35	enough	enough	ADJ
admet-162	62	36	to	to	PART
admet-162	62	37	produce	produce	VERB
admet-162	62	38	the	the	DET
admet-162	62	39	impairment	impairment	NOUN
admet-162	62	40	of	of	ADP
admet-162	62	41	aeds	aed	NOUN
admet-162	62	42	entrance	entrance	NOUN
admet-162	62	43	in	in	ADP
admet-162	62	44	the	the	DET
admet-162	62	45	brain	brain	NOUN
admet-162	62	46	for	for	ADP
admet-162	62	47	the	the	DET
admet-162	62	48	responders	responder	NOUN
admet-162	62	49	patients	patient	NOUN
admet-162	62	50	.	.	PUNCT
admet-162	63	1	the	the	DET
admet-162	63	2	“	"	PUNCT
admet-162	63	3	transporter`s	transporter`s	PRON
admet-162	63	4	hypothesis	hypothesis	NOUN
admet-162	63	5	”	"	PUNCT
admet-162	63	6	to	to	PART
admet-162	63	7	explain	explain	VERB
admet-162	63	8	the	the	DET
admet-162	63	9	refractoriness	refractoriness	NOUN
admet-162	63	10	in	in	ADP
admet-162	63	11	epilepsy	epilepsy	NOUN
admet-162	63	12	need	need	VERB
admet-162	63	13	not	not	PART
admet-162	63	14	only	only	ADV
admet-162	63	15	a	a	DET
admet-162	63	16	functional	functional	ADJ
admet-162	63	17	up	up	NOUN
admet-162	63	18	-	-	PUNCT
admet-162	63	19	regulation	regulation	NOUN
admet-162	63	20	of	of	ADP
admet-162	63	21	these	these	DET
admet-162	63	22	transporters	transporter	NOUN
admet-162	63	23	at	at	ADP
admet-162	63	24	bbb	bbb	PROPN
admet-162	63	25	level	level	NOUN
admet-162	63	26	to	to	PART
admet-162	63	27	clean	clean	VERB
admet-162	63	28	/	/	SYM
admet-162	63	29	export	export	NOUN
admet-162	63	30	aeds	aed	NOUN
admet-162	63	31	,	,	PUNCT
admet-162	63	32	but	but	CCONJ
admet-162	63	33	also	also	ADV
admet-162	63	34	they	they	PRON
admet-162	63	35	should	should	AUX
admet-162	63	36	be	be	AUX
admet-162	63	37	expressed	express	VERB
admet-162	63	38	on	on	ADP
admet-162	63	39	previously	previously	ADV
admet-162	63	40	non	non	ADJ
admet-162	63	41	-	-	ADJ
admet-162	63	42	expressing	express	VERB
admet-162	63	43	cell	cell	NOUN
admet-162	63	44	as	as	ADP
admet-162	63	45	neurons	neuron	NOUN
admet-162	63	46	.	.	PUNCT
admet-162	64	1	the	the	DET
admet-162	64	2	inducible	inducible	ADJ
admet-162	64	3	properties	property	NOUN
admet-162	64	4	of	of	ADP
admet-162	64	5	these	these	DET
admet-162	64	6	transporters	transporter	NOUN
admet-162	64	7	as	as	ADV
admet-162	64	8	well	well	ADV
admet-162	64	9	as	as	ADP
admet-162	64	10	the	the	DET
admet-162	64	11	the	the	DET
admet-162	64	12	pharmacoresistant	pharmacoresistant	ADJ
admet-162	64	13	phenotype	phenotype	NOUN
admet-162	64	14	[	[	X
admet-162	64	15	9	9	NUM
admet-162	64	16	]	]	PUNCT
admet-162	64	17	links	link	NOUN
admet-162	64	18	pharmacoresistance	pharmacoresistance	ADV
admet-162	64	19	with	with	ADP
admet-162	64	20	epileptogenesis	epileptogenesis	NOUN
admet-162	64	21	,	,	PUNCT
admet-162	64	22	as	as	SCONJ
admet-162	64	23	discussed	discuss	VERB
admet-162	64	24	below	below	ADV
admet-162	64	25	.	.	PUNCT
admet-162	65	1	p	p	X
admet-162	65	2	-	-	PUNCT
admet-162	65	3	glycoprotein	glycoprotein	NOUN
admet-162	65	4	and	and	CCONJ
admet-162	65	5	drug	drug	NOUN
admet-162	65	6	resistant	resistant	ADJ
admet-162	65	7	phenotype	phenotype	NOUN
admet-162	65	8	in	in	ADP
admet-162	65	9	epilepsy	epilepsy	NOUN
admet-162	65	10	one	one	NUM
admet-162	65	11	-	-	PUNCT
admet-162	65	12	half	half	NOUN
admet-162	65	13	of	of	ADP
admet-162	65	14	newly	newly	ADV
admet-162	65	15	diagnosed	diagnose	VERB
admet-162	65	16	patients	patient	NOUN
admet-162	65	17	with	with	ADP
admet-162	65	18	epilepsy	epilepsy	NOUN
admet-162	65	19	obtain	obtain	VERB
admet-162	65	20	full	full	ADJ
admet-162	65	21	seizure	seizure	NOUN
admet-162	65	22	control	control	NOUN
admet-162	65	23	with	with	ADP
admet-162	65	24	the	the	DET
admet-162	65	25	first	first	ADJ
admet-162	65	26	aed	aed	NOUN
admet-162	65	27	trial	trial	NOUN
admet-162	65	28	,	,	PUNCT
admet-162	65	29	and	and	CCONJ
admet-162	65	30	13	13	NUM
admet-162	65	31	%	%	NOUN
admet-162	65	32	more	more	ADJ
admet-162	65	33	enter	enter	VERB
admet-162	65	34	remission	remission	NOUN
admet-162	65	35	with	with	ADP
admet-162	65	36	the	the	DET
admet-162	65	37	addition	addition	NOUN
admet-162	65	38	of	of	ADP
admet-162	65	39	a	a	DET
admet-162	65	40	second	second	ADJ
admet-162	65	41	drug	drug	NOUN
admet-162	65	42	.	.	PUNCT
admet-162	66	1	however	however	ADV
admet-162	66	2	,	,	PUNCT
admet-162	66	3	the	the	DET
admet-162	66	4	30	30	NUM
admet-162	66	5	-	-	SYM
admet-162	66	6	40	40	NUM
admet-162	66	7	%	%	NOUN
admet-162	66	8	of	of	ADP
admet-162	66	9	the	the	DET
admet-162	66	10	remaining	remain	VERB
admet-162	66	11	patients	patient	NOUN
admet-162	66	12	are	be	AUX
admet-162	66	13	not	not	PART
admet-162	66	14	to	to	PART
admet-162	66	15	obtain	obtain	VERB
admet-162	66	16	satisfactory	satisfactory	ADJ
admet-162	66	17	seizure	seizure	NOUN
admet-162	66	18	control	control	NOUN
admet-162	66	19	in	in	ADP
admet-162	66	20	spite	spite	NOUN
admet-162	66	21	of	of	ADP
admet-162	66	22	different	different	ADJ
admet-162	66	23	drug	drug	NOUN
admet-162	66	24	combinations	combination	NOUN
admet-162	66	25	.	.	PUNCT
admet-162	67	1	it	it	PRON
admet-162	67	2	is	be	AUX
admet-162	67	3	clear	clear	ADJ
admet-162	67	4	the	the	DET
admet-162	67	5	wrong	wrong	ADJ
admet-162	67	6	choice	choice	NOUN
admet-162	67	7	of	of	ADP
admet-162	67	8	aeds	aed	NOUN
admet-162	67	9	may	may	AUX
admet-162	67	10	be	be	AUX
admet-162	67	11	the	the	DET
admet-162	67	12	cause	cause	NOUN
admet-162	67	13	of	of	ADP
admet-162	67	14	treatment	treatment	NOUN
admet-162	67	15	failure	failure	NOUN
admet-162	67	16	.	.	PUNCT
admet-162	68	1	however	however	ADV
admet-162	68	2	,	,	PUNCT
admet-162	68	3	with	with	ADP
admet-162	68	4	the	the	DET
admet-162	68	5	correct	correct	ADJ
admet-162	68	6	therapeutic	therapeutic	ADJ
admet-162	68	7	stratagem	stratagem	NOUN
admet-162	68	8	,	,	PUNCT
admet-162	68	9	sanjay	sanjay	PROPN
admet-162	68	10	m.	m.	PROPN
admet-162	68	11	sisodiya	sisodiya	PROPN
admet-162	68	12	(	(	PUNCT
admet-162	68	13	2006	2006	NUM
admet-162	68	14	)	)	PUNCT
admet-162	68	15	suggests	suggest	VERB
admet-162	68	16	that	that	SCONJ
admet-162	68	17	patients	patient	NOUN
admet-162	68	18	,	,	PUNCT
admet-162	68	19	who	who	PRON
admet-162	68	20	were	be	AUX
admet-162	68	21	considered	consider	VERB
admet-162	68	22	drug	drug	NOUN
admet-162	68	23	resistant	resistant	ADJ
admet-162	68	24	,	,	PUNCT
admet-162	68	25	may	may	AUX
admet-162	68	26	not	not	PART
admet-162	68	27	remain	remain	VERB
admet-162	68	28	so	so	ADV
admet-162	68	29	as	as	SCONJ
admet-162	68	30	newer	new	ADJ
admet-162	68	31	aeds	aed	NOUN
admet-162	68	32	are	be	AUX
admet-162	68	33	developed	develop	VERB
admet-162	68	34	or	or	CCONJ
admet-162	68	35	designed	design	VERB
admet-162	68	36	to	to	ADP
admet-162	68	37	new	new	ADJ
admet-162	68	38	target	target	NOUN
admet-162	68	39	previously	previously	ADV
admet-162	68	40	unappreciated	unappreciate	VERB
admet-162	68	41	underlying	underlying	ADJ
admet-162	68	42	pathophysiological	pathophysiological	ADJ
admet-162	68	43	mechanisms	mechanism	NOUN
admet-162	68	44	.	.	PUNCT
admet-162	69	1	additionally	additionally	ADV
admet-162	69	2	,	,	PUNCT
admet-162	69	3	he	he	PRON
admet-162	69	4	suggests	suggest	VERB
admet-162	69	5	that	that	SCONJ
admet-162	69	6	for	for	ADP
admet-162	69	7	individuals	individual	NOUN
admet-162	69	8	who	who	PRON
admet-162	69	9	we	we	PRON
admet-162	69	10	could	could	AUX
admet-162	69	11	define	define	VERB
admet-162	69	12	as	as	ADP
admet-162	69	13	being	be	AUX
admet-162	69	14	drug	drug	NOUN
admet-162	69	15	resistant	resistant	ADJ
admet-162	69	16	,	,	PUNCT
admet-162	69	17	perhaps	perhaps	ADV
admet-162	69	18	their	their	PRON
admet-162	69	19	epilepsy	epilepsy	NOUN
admet-162	69	20	is	be	AUX
admet-162	69	21	considered	consider	VERB
admet-162	69	22	“	"	PUNCT
admet-162	69	23	drug	drug	NOUN
admet-162	69	24	resistant	resistant	ADJ
admet-162	69	25	”	"	PUNCT
admet-162	69	26	simply	simply	ADV
admet-162	69	27	because	because	SCONJ
admet-162	69	28	we	we	PRON
admet-162	69	29	do	do	AUX
admet-162	69	30	not	not	PART
admet-162	69	31	yet	yet	ADV
admet-162	69	32	have	have	VERB
admet-162	69	33	the	the	DET
admet-162	69	34	appropriate	appropriate	ADJ
admet-162	69	35	drugs	drug	NOUN
admet-162	69	36	for	for	ADP
admet-162	69	37	the	the	DET
admet-162	69	38	treatment	treatment	NOUN
admet-162	69	39	[	[	X
admet-162	69	40	21	21	NUM
admet-162	69	41	]	]	PUNCT
admet-162	69	42	.	.	PUNCT
admet-162	70	1	however	however	ADV
admet-162	70	2	,	,	PUNCT
admet-162	70	3	in	in	ADP
admet-162	70	4	spite	spite	NOUN
admet-162	70	5	of	of	ADP
admet-162	70	6	the	the	DET
admet-162	70	7	increased	increase	VERB
admet-162	70	8	amount	amount	NOUN
admet-162	70	9	of	of	ADP
admet-162	70	10	new	new	ADJ
admet-162	70	11	aeds	aed	NOUN
admet-162	70	12	developed	develop	VERB
admet-162	70	13	during	during	ADP
admet-162	70	14	the	the	DET
admet-162	70	15	last	last	ADJ
admet-162	70	16	30	30	NUM
admet-162	70	17	years	year	NOUN
admet-162	70	18	,	,	PUNCT
admet-162	70	19	the	the	DET
admet-162	70	20	same	same	ADJ
admet-162	70	21	percentage	percentage	NOUN
admet-162	70	22	(	(	PUNCT
admet-162	70	23	30	30	NUM
admet-162	70	24	-	-	SYM
admet-162	70	25	40	40	NUM
admet-162	70	26	%	%	NOUN
admet-162	70	27	)	)	PUNCT
admet-162	70	28	of	of	ADP
admet-162	70	29	pharmacoresistant	pharmacoresistant	ADJ
admet-162	70	30	patients	patient	NOUN
admet-162	70	31	remains	remain	VERB
admet-162	70	32	without	without	ADP
admet-162	70	33	modifications	modification	NOUN
admet-162	70	34	(	(	PUNCT
admet-162	70	35	fig	fig	NOUN
admet-162	70	36	.	.	PUNCT
admet-162	71	1	2	2	NUM
admet-162	71	2	)	)	PUNCT
admet-162	71	3	.	.	PUNCT
admet-162	72	1	lazarowski	lazarowski	PROPN
admet-162	72	2	et	et	PROPN
admet-162	72	3	al	al	PROPN
admet-162	72	4	.	.	PROPN
admet-162	72	5	admet	admet	PROPN
admet-162	72	6	&	&	CCONJ
admet-162	72	7	dmpk	dmpk	PROPN
admet-162	72	8	3(2	3(2	NUM
admet-162	72	9	)	)	PUNCT
admet-162	72	10	(	(	PUNCT
admet-162	72	11	2015	2015	NUM
admet-162	72	12	)	)	PUNCT
admet-162	72	13	110	110	NUM
admet-162	72	14	-	-	SYM
admet-162	72	15	121	121	NUM
admet-162	72	16	114	114	NUM
admet-162	72	17	figure	figure	NOUN
admet-162	72	18	2	2	NUM
admet-162	72	19	:	:	PUNCT
admet-162	72	20	the	the	DET
admet-162	72	21	increase	increase	NOUN
admet-162	72	22	of	of	ADP
admet-162	72	23	new	new	ADJ
admet-162	72	24	aeds	aed	NOUN
admet-162	72	25	not	not	PART
admet-162	72	26	decrease	decrease	VERB
admet-162	72	27	the	the	DET
admet-162	72	28	percentage	percentage	NOUN
admet-162	72	29	of	of	ADP
admet-162	72	30	drug	drug	NOUN
admet-162	72	31	-	-	PUNCT
admet-162	72	32	resistant	resistant	ADJ
admet-162	72	33	cases	case	NOUN
admet-162	72	34	(	(	PUNCT
admet-162	72	35	modified	modify	VERB
admet-162	72	36	from	from	ADP
admet-162	72	37	czornyj	czornyj	NOUN
admet-162	72	38	&	&	CCONJ
admet-162	72	39	lazarowski	lazarowski	PROPN
admet-162	72	40	:	:	PUNCT
admet-162	72	41	genetics	genetic	NOUN
admet-162	72	42	of	of	ADP
admet-162	72	43	epilepsy	epilepsy	NOUN
admet-162	72	44	and	and	CCONJ
admet-162	72	45	refractory	refractory	NOUN
admet-162	72	46	epilepsy	epilepsy	NOUN
admet-162	72	47	.	.	PUNCT
admet-162	73	1	ed	ed	NOUN
admet-162	73	2	.	.	PUNCT
admet-162	74	1	michael	michael	PROPN
admet-162	74	2	dean	dean	PROPN
admet-162	74	3	.	.	PUNCT
admet-162	75	1	colloquium	colloquium	NOUN
admet-162	75	2	series	series	NOUN
admet-162	75	3	on	on	ADP
admet-162	75	4	the	the	DET
admet-162	75	5	genetic	genetic	ADJ
admet-162	75	6	basis	basis	NOUN
admet-162	75	7	of	of	ADP
admet-162	75	8	human	human	ADJ
admet-162	75	9	disease	disease	NOUN
admet-162	75	10	,	,	PUNCT
admet-162	75	11	morgan	morgan	PROPN
admet-162	75	12	&	&	CCONJ
admet-162	75	13	claypool	claypool	PROPN
admet-162	75	14	life	life	NOUN
admet-162	75	15	sciences	sciences	PROPN
admet-162	75	16	,	,	PUNCT
admet-162	75	17	2013	2013	NUM
admet-162	75	18	)	)	PUNCT
admet-162	75	19	after	after	ADP
admet-162	75	20	the	the	DET
admet-162	75	21	initial	initial	ADJ
admet-162	75	22	descriptions	description	NOUN
admet-162	75	23	of	of	ADP
admet-162	75	24	the	the	DET
admet-162	75	25	potential	potential	ADJ
admet-162	75	26	association	association	NOUN
admet-162	75	27	between	between	ADP
admet-162	75	28	p	p	NOUN
admet-162	75	29	-	-	PUNCT
admet-162	75	30	gp	gp	NOUN
admet-162	75	31	overexpression	overexpression	NOUN
admet-162	75	32	in	in	ADP
admet-162	75	33	the	the	DET
admet-162	75	34	brain	brain	NOUN
admet-162	75	35	and	and	CCONJ
admet-162	75	36	refractory	refractory	NOUN
admet-162	75	37	epilepsy	epilepsy	NOUN
admet-162	75	38	[	[	X
admet-162	75	39	22,23	22,23	NOUN
admet-162	75	40	]	]	X
admet-162	75	41	,	,	PUNCT
admet-162	75	42	several	several	ADJ
admet-162	75	43	other	other	ADJ
admet-162	75	44	groups	group	NOUN
admet-162	75	45	have	have	AUX
admet-162	75	46	reported	report	VERB
admet-162	75	47	high	high	ADJ
admet-162	75	48	levels	level	NOUN
admet-162	75	49	of	of	ADP
admet-162	75	50	p	p	NOUN
admet-162	75	51	-	-	PUNCT
admet-162	75	52	gp	gp	NOUN
admet-162	75	53	expression	expression	NOUN
admet-162	75	54	in	in	ADP
admet-162	75	55	epileptogenic	epileptogenic	ADJ
admet-162	75	56	brain	brain	NOUN
admet-162	75	57	specimens	specimen	NOUN
admet-162	75	58	from	from	ADP
admet-162	75	59	patients	patient	NOUN
admet-162	75	60	with	with	ADP
admet-162	75	61	refractory	refractory	NOUN
admet-162	75	62	epilepsy	epilepsy	NOUN
admet-162	75	63	.	.	PUNCT
admet-162	76	1	in	in	ADP
admet-162	76	2	these	these	DET
admet-162	76	3	studies	study	NOUN
admet-162	76	4	,	,	PUNCT
admet-162	76	5	p	p	NOUN
admet-162	76	6	-	-	PUNCT
admet-162	76	7	gp	gp	NOUN
admet-162	76	8	was	be	AUX
admet-162	76	9	highly	highly	ADV
admet-162	76	10	expressed	express	VERB
admet-162	76	11	not	not	PART
admet-162	76	12	only	only	ADV
admet-162	76	13	in	in	ADP
admet-162	76	14	endothelial	endothelial	ADJ
admet-162	76	15	cells	cell	NOUN
admet-162	76	16	of	of	ADP
admet-162	76	17	bbb	bbb	PROPN
admet-162	76	18	but	but	CCONJ
admet-162	76	19	also	also	ADV
admet-162	76	20	in	in	ADP
admet-162	76	21	brain	brain	NOUN
admet-162	76	22	parenchymal	parenchymal	ADJ
admet-162	76	23	cells	cell	NOUN
admet-162	76	24	[	[	X
admet-162	76	25	9,10,24	9,10,24	NUM
admet-162	76	26	-	-	SYM
admet-162	76	27	26	26	NUM
admet-162	76	28	]	]	PUNCT
admet-162	76	29	.	.	PUNCT
admet-162	77	1	similar	similar	ADJ
admet-162	77	2	results	result	NOUN
admet-162	77	3	were	be	AUX
admet-162	77	4	observed	observe	VERB
admet-162	77	5	by	by	ADP
admet-162	77	6	independent	independent	ADJ
admet-162	77	7	experimental	experimental	ADJ
admet-162	77	8	studies	study	NOUN
admet-162	77	9	of	of	ADP
admet-162	77	10	different	different	ADJ
admet-162	77	11	epileptic	epileptic	ADJ
admet-162	77	12	models	model	NOUN
admet-162	77	13	,	,	PUNCT
admet-162	77	14	such	such	ADJ
admet-162	77	15	as	as	ADP
admet-162	77	16	a	a	DET
admet-162	77	17	single	single	ADJ
admet-162	77	18	dose	dose	NOUN
admet-162	77	19	of	of	ADP
admet-162	77	20	intra	intra	ADJ
admet-162	77	21	-	-	ADJ
admet-162	77	22	cerebroventricular	cerebroventricular	ADJ
admet-162	77	23	kainic	kainic	ADJ
admet-162	77	24	acid	acid	NOUN
admet-162	77	25	,	,	PUNCT
admet-162	77	26	chronic	chronic	ADJ
admet-162	77	27	epilepsy	epilepsy	NOUN
admet-162	77	28	,	,	PUNCT
admet-162	77	29	repetitive	repetitive	ADJ
admet-162	77	30	ptz	ptz	ADJ
admet-162	77	31	-	-	ADJ
admet-162	77	32	induced	induced	ADJ
admet-162	77	33	seizures	seizure	NOUN
admet-162	77	34	and	and	CCONJ
admet-162	77	35	pilocarpine	pilocarpine	NOUN
admet-162	77	36	-	-	PUNCT
admet-162	77	37	induced	induce	VERB
admet-162	77	38	status	status	NOUN
admet-162	77	39	epilepticus	epilepticus	VERB
admet-162	77	40	.	.	PUNCT
admet-162	78	1	in	in	ADP
admet-162	78	2	these	these	DET
admet-162	78	3	studies	study	NOUN
admet-162	78	4	,	,	PUNCT
admet-162	78	5	seizure	seizure	NOUN
admet-162	78	6	-	-	PUNCT
admet-162	78	7	induced	induce	VERB
admet-162	78	8	overexpression	overexpression	NOUN
admet-162	78	9	of	of	ADP
admet-162	78	10	p	p	NOUN
admet-162	78	11	-	-	PUNCT
admet-162	78	12	gp	gp	NOUN
admet-162	78	13	at	at	ADP
admet-162	78	14	bbb	bbb	NOUN
admet-162	78	15	and	and	CCONJ
admet-162	78	16	brain	brain	NOUN
admet-162	78	17	parenchyma	parenchyma	NOUN
admet-162	78	18	cells	cell	NOUN
admet-162	78	19	as	as	ADP
admet-162	78	20	astrocytes	astrocyte	NOUN
admet-162	78	21	and	and	CCONJ
admet-162	78	22	neurons	neuron	NOUN
admet-162	78	23	were	be	AUX
admet-162	78	24	described	describe	VERB
admet-162	78	25	[	[	PUNCT
admet-162	78	26	25,27	25,27	NUM
admet-162	78	27	-	-	SYM
admet-162	78	28	29	29	NUM
admet-162	78	29	]	]	PUNCT
admet-162	78	30	.	.	PUNCT
admet-162	79	1	furthermore	furthermore	ADV
admet-162	79	2	,	,	PUNCT
admet-162	79	3	after	after	ADP
admet-162	79	4	repetitive	repetitive	ADJ
admet-162	79	5	induced	induced	ADJ
admet-162	79	6	seizures	seizure	NOUN
admet-162	79	7	,	,	PUNCT
admet-162	79	8	the	the	DET
admet-162	79	9	simultaneous	simultaneous	ADJ
admet-162	79	10	high	high	ADJ
admet-162	79	11	p	p	NOUN
admet-162	79	12	-	-	PUNCT
admet-162	79	13	gp	gp	NOUN
admet-162	79	14	expressions	expression	NOUN
admet-162	79	15	in	in	ADP
admet-162	79	16	different	different	ADJ
admet-162	79	17	brain	brain	NOUN
admet-162	79	18	regions	region	NOUN
admet-162	79	19	and	and	CCONJ
admet-162	79	20	liver	liver	NOUN
admet-162	79	21	or	or	CCONJ
admet-162	79	22	heart	heart	NOUN
admet-162	79	23	have	have	AUX
admet-162	79	24	been	be	AUX
admet-162	79	25	reported	report	VERB
admet-162	79	26	[	[	X
admet-162	79	27	30,31	30,31	NUM
admet-162	79	28	]	]	PUNCT
admet-162	79	29	.	.	PUNCT
admet-162	80	1	p	p	X
admet-162	80	2	-	-	PUNCT
admet-162	80	3	glycoprotein	glycoprotein	NOUN
admet-162	80	4	and	and	CCONJ
admet-162	80	5	pharmacokinetics	pharmacokinetic	NOUN
admet-162	80	6	alterations	alteration	NOUN
admet-162	80	7	refractory	refractory	NOUN
admet-162	80	8	epilepsy	epilepsy	NOUN
admet-162	80	9	is	be	AUX
admet-162	80	10	described	describe	VERB
admet-162	80	11	in	in	ADP
admet-162	80	12	patients	patient	NOUN
admet-162	80	13	receiving	receive	VERB
admet-162	80	14	recommended	recommend	VERB
admet-162	80	15	aeds	aed	NOUN
admet-162	80	16	doses	dose	NOUN
admet-162	80	17	,	,	PUNCT
admet-162	80	18	have	have	VERB
admet-162	80	19	an	an	DET
admet-162	80	20	adequate	adequate	ADJ
admet-162	80	21	therapeutic	therapeutic	ADJ
admet-162	80	22	levels	level	NOUN
admet-162	80	23	of	of	ADP
admet-162	80	24	aeds	aed	NOUN
admet-162	80	25	in	in	ADP
admet-162	80	26	plasma	plasma	NOUN
admet-162	80	27	,	,	PUNCT
admet-162	80	28	but	but	CCONJ
admet-162	80	29	remains	remain	VERB
admet-162	80	30	without	without	ADP
admet-162	80	31	control	control	NOUN
admet-162	80	32	of	of	ADP
admet-162	80	33	seizures	seizure	NOUN
admet-162	80	34	.	.	PUNCT
admet-162	81	1	it	it	PRON
admet-162	81	2	was	be	AUX
admet-162	81	3	demonstrated	demonstrate	VERB
admet-162	81	4	that	that	SCONJ
admet-162	81	5	therapeutic	therapeutic	ADJ
admet-162	81	6	levels	level	NOUN
admet-162	81	7	of	of	ADP
admet-162	81	8	phenytoin	phenytoin	PROPN
admet-162	81	9	(	(	PUNCT
admet-162	81	10	pht	pht	PROPN
admet-162	81	11	)	)	PUNCT
admet-162	81	12	in	in	ADP
admet-162	81	13	blood	blood	NOUN
admet-162	81	14	and	and	CCONJ
admet-162	81	15	csf	csf	NOUN
admet-162	81	16	can	can	AUX
admet-162	81	17	be	be	AUX
admet-162	81	18	achieved	achieve	VERB
admet-162	81	19	independently	independently	ADV
admet-162	81	20	of	of	ADP
admet-162	81	21	the	the	DET
admet-162	81	22	route	route	NOUN
admet-162	81	23	of	of	ADP
admet-162	81	24	administration	administration	NOUN
admet-162	81	25	,	,	PUNCT
admet-162	81	26	as	as	ADV
admet-162	81	27	long	long	ADV
admet-162	81	28	as	as	SCONJ
admet-162	81	29	conventional	conventional	ADJ
admet-162	81	30	loading	loading	NOUN
admet-162	81	31	doses	dose	NOUN
admet-162	81	32	are	be	AUX
admet-162	81	33	used	use	VERB
admet-162	81	34	,	,	PUNCT
admet-162	81	35	and	and	CCONJ
admet-162	81	36	in	in	ADP
admet-162	81	37	the	the	DET
admet-162	81	38	case	case	NOUN
admet-162	81	39	of	of	ADP
admet-162	81	40	pht	pht	PROPN
admet-162	81	41	i.v	i.v	PROPN
admet-162	81	42	.	.	PROPN
admet-162	81	43	administration	administration	PROPN
admet-162	81	44	,	,	PUNCT
admet-162	81	45	2	2	NUM
admet-162	81	46	h	h	NOUN
admet-162	81	47	are	be	AUX
admet-162	81	48	enough	enough	ADJ
admet-162	81	49	to	to	PART
admet-162	81	50	reach	reach	VERB
admet-162	81	51	steady	steady	ADJ
admet-162	81	52	state	state	NOUN
admet-162	81	53	concentrations	concentration	NOUN
admet-162	81	54	within	within	ADP
admet-162	81	55	the	the	DET
admet-162	81	56	therapeutic	therapeutic	ADJ
admet-162	81	57	range	range	NOUN
admet-162	82	1	[	[	X
admet-162	82	2	32	32	NUM
admet-162	82	3	]	]	PUNCT
admet-162	82	4	.	.	PUNCT
admet-162	83	1	as	as	SCONJ
admet-162	83	2	previously	previously	ADV
admet-162	83	3	described	describe	VERB
admet-162	83	4	in	in	ADP
admet-162	83	5	two	two	NUM
admet-162	83	6	cases	case	NOUN
admet-162	83	7	reports	report	NOUN
admet-162	83	8	[	[	X
admet-162	83	9	23,33	23,33	NUM
admet-162	83	10	]	]	X
admet-162	83	11	,	,	PUNCT
admet-162	83	12	patients	patient	NOUN
admet-162	83	13	can	can	AUX
admet-162	83	14	have	have	VERB
admet-162	83	15	persistent	persistent	ADJ
admet-162	83	16	low	low	ADJ
admet-162	83	17	plasmatic	plasmatic	ADJ
admet-162	83	18	levels	level	NOUN
admet-162	83	19	of	of	ADP
admet-162	83	20	at	at	ADV
admet-162	83	21	least	least	ADJ
admet-162	83	22	one	one	NUM
admet-162	83	23	of	of	ADP
admet-162	83	24	the	the	DET
admet-162	83	25	aeds	aed	NOUN
admet-162	83	26	administered	administer	VERB
admet-162	83	27	,	,	PUNCT
admet-162	83	28	despite	despite	SCONJ
admet-162	83	29	their	their	PRON
admet-162	83	30	scrupulous	scrupulous	ADJ
admet-162	83	31	compliance	compliance	NOUN
admet-162	83	32	with	with	ADP
admet-162	83	33	the	the	DET
admet-162	83	34	prescribed	prescribed	ADJ
admet-162	83	35	drugs	drug	NOUN
admet-162	83	36	regimen	regiman	NOUN
admet-162	83	37	.	.	PUNCT
admet-162	84	1	often	often	ADV
admet-162	84	2	,	,	PUNCT
admet-162	84	3	laboratory	laboratory	NOUN
admet-162	84	4	professionals	professional	NOUN
admet-162	84	5	and	and	CCONJ
admet-162	84	6	physicians	physician	NOUN
admet-162	84	7	have	have	VERB
admet-162	84	8	no	no	DET
admet-162	84	9	rational	rational	ADJ
admet-162	84	10	explanations	explanation	NOUN
admet-162	84	11	,	,	PUNCT
admet-162	84	12	and	and	CCONJ
admet-162	84	13	non	non	ADJ
admet-162	84	14	-	-	ADJ
admet-162	84	15	detectable	detectable	ADJ
admet-162	84	16	errors	error	NOUN
admet-162	84	17	in	in	ADP
admet-162	84	18	aed	aed	NOUN
admet-162	84	19	measurement	measurement	NOUN
admet-162	84	20	procedures	procedure	NOUN
admet-162	84	21	and	and	CCONJ
admet-162	84	22	methods	method	NOUN
admet-162	84	23	are	be	AUX
admet-162	84	24	assumed	assume	VERB
admet-162	84	25	.	.	PUNCT
admet-162	85	1	most	most	ADJ
admet-162	85	2	aeds	aed	NOUN
admet-162	85	3	are	be	AUX
admet-162	85	4	substrates	substrate	NOUN
admet-162	85	5	of	of	ADP
admet-162	85	6	p	p	NOUN
admet-162	85	7	-	-	PUNCT
admet-162	85	8	gp	gp	NOUN
admet-162	85	9	,	,	PUNCT
admet-162	85	10	and	and	CCONJ
admet-162	85	11	the	the	DET
admet-162	85	12	inducible	inducible	ADJ
admet-162	85	13	nature	nature	NOUN
admet-162	85	14	of	of	ADP
admet-162	85	15	this	this	DET
admet-162	85	16	abc	abc	PROPN
admet-162	85	17	-	-	PUNCT
admet-162	85	18	transporter	transporter	NOUN
admet-162	85	19	gene	gene	NOUN
admet-162	85	20	suggests	suggest	VERB
admet-162	85	21	that	that	SCONJ
admet-162	85	22	over	over	ADP
admet-162	85	23	-	-	PUNCT
admet-162	85	24	expression	expression	NOUN
admet-162	85	25	of	of	ADP
admet-162	85	26	this	this	DET
admet-162	85	27	protein	protein	NOUN
admet-162	85	28	can	can	AUX
admet-162	85	29	be	be	AUX
admet-162	85	30	observed	observe	VERB
admet-162	85	31	in	in	ADP
admet-162	85	32	all	all	DET
admet-162	85	33	admet	admet	PROPN
admet-162	85	34	&	&	CCONJ
admet-162	85	35	dmpk	dmpk	PROPN
admet-162	85	36	3(2	3(2	NUM
admet-162	85	37	)	)	PUNCT
admet-162	85	38	(	(	PUNCT
admet-162	85	39	2015	2015	NUM
admet-162	85	40	)	)	PUNCT
admet-162	85	41	110	110	NUM
admet-162	85	42	-	-	SYM
admet-162	85	43	121	121	NUM
admet-162	85	44	the	the	DET
admet-162	85	45	roles	role	NOUN
admet-162	85	46	of	of	ADP
admet-162	85	47	p	p	NOUN
admet-162	85	48	-	-	PUNCT
admet-162	85	49	gp	gp	NOUN
admet-162	85	50	in	in	ADP
admet-162	85	51	refractory	refractory	NOUN
admet-162	85	52	epilepsy	epilepsy	NOUN
admet-162	85	53	doi	doi	NOUN
admet-162	85	54	:	:	PUNCT
admet-162	85	55	10.5599	10.5599	NUM
admet-162	85	56	/	/	SYM
admet-162	85	57	admet.3.2.162	admet.3.2.162	ADP
admet-162	85	58	115	115	NUM
admet-162	85	59	excretory	excretory	NOUN
admet-162	85	60	organs	organ	NOUN
admet-162	85	61	including	include	VERB
admet-162	85	62	bbb	bbb	NOUN
admet-162	85	63	,	,	PUNCT
admet-162	85	64	playing	play	VERB
admet-162	85	65	a	a	DET
admet-162	85	66	critical	critical	ADJ
admet-162	85	67	role	role	NOUN
admet-162	85	68	in	in	ADP
admet-162	85	69	the	the	DET
admet-162	85	70	modification	modification	NOUN
admet-162	85	71	of	of	ADP
admet-162	85	72	both	both	CCONJ
admet-162	85	73	systemic	systemic	ADJ
admet-162	85	74	and	and	CCONJ
admet-162	85	75	local	local	ADJ
admet-162	85	76	pharmacokinetics	pharmacokinetic	NOUN
admet-162	85	77	of	of	ADP
admet-162	85	78	aeds	aed	NOUN
admet-162	85	79	.	.	PUNCT
admet-162	86	1	experimentally	experimentally	ADV
admet-162	86	2	,	,	PUNCT
admet-162	86	3	it	it	PRON
admet-162	86	4	was	be	AUX
admet-162	86	5	also	also	ADV
admet-162	86	6	demonstrated	demonstrate	VERB
admet-162	86	7	that	that	SCONJ
admet-162	86	8	brain	brain	NOUN
admet-162	86	9	p	p	NOUN
admet-162	86	10	-	-	PUNCT
admet-162	86	11	gp	gp	NOUN
admet-162	86	12	overexpression	overexpression	NOUN
admet-162	86	13	,	,	PUNCT
admet-162	86	14	correlated	correlate	VERB
admet-162	86	15	with	with	ADP
admet-162	86	16	the	the	DET
admet-162	86	17	lower	low	ADJ
admet-162	86	18	hippocampal	hippocampal	ADJ
admet-162	86	19	phenytoin	phenytoin	NOUN
admet-162	86	20	concentration	concentration	NOUN
admet-162	86	21	in	in	ADP
admet-162	86	22	a	a	DET
admet-162	86	23	refractory	refractory	NOUN
admet-162	86	24	epileptic	epileptic	ADJ
admet-162	86	25	model	model	NOUN
admet-162	86	26	,	,	PUNCT
admet-162	86	27	and	and	CCONJ
admet-162	86	28	whereas	whereas	SCONJ
admet-162	86	29	the	the	DET
admet-162	86	30	administration	administration	NOUN
admet-162	86	31	of	of	ADP
admet-162	86	32	an	an	DET
admet-162	86	33	antagonist	antagonist	NOUN
admet-162	86	34	of	of	ADP
admet-162	86	35	p	p	NOUN
admet-162	86	36	-	-	PUNCT
admet-162	86	37	gp	gp	NOUN
admet-162	86	38	such	such	ADJ
admet-162	86	39	as	as	ADP
admet-162	86	40	nimodipine	nimodipine	ADJ
admet-162	86	41	(	(	PUNCT
admet-162	86	42	2	2	NUM
admet-162	86	43	mg	mg	PROPN
admet-162	86	44	/	/	SYM
admet-162	86	45	kg	kg	NOUN
admet-162	86	46	)	)	PUNCT
admet-162	86	47	restored	restore	VERB
admet-162	86	48	the	the	DET
admet-162	86	49	normal	normal	ADJ
admet-162	86	50	central	central	ADJ
admet-162	86	51	pht	pht	NOUN
admet-162	86	52	pharmacokinetics	pharmacokinetic	NOUN
admet-162	87	1	[	[	X
admet-162	87	2	34	34	NUM
admet-162	87	3	]	]	PUNCT
admet-162	87	4	.	.	PUNCT
admet-162	88	1	clinically	clinically	ADV
admet-162	88	2	and	and	CCONJ
admet-162	88	3	experimentally	experimentally	ADV
admet-162	88	4	,	,	PUNCT
admet-162	88	5	the	the	DET
admet-162	88	6	uses	use	NOUN
admet-162	88	7	of	of	ADP
admet-162	88	8	some	some	DET
admet-162	88	9	calcium	calcium	NOUN
admet-162	88	10	channel	channel	NOUN
admet-162	88	11	blockers	blocker	NOUN
admet-162	88	12	have	have	AUX
admet-162	88	13	been	be	AUX
admet-162	88	14	described	describe	VERB
admet-162	88	15	to	to	PART
admet-162	88	16	increase	increase	VERB
admet-162	88	17	plasmatic	plasmatic	ADJ
admet-162	88	18	levels	level	NOUN
admet-162	88	19	of	of	ADP
admet-162	88	20	aeds	aed	NOUN
admet-162	88	21	simultaneously	simultaneously	ADV
admet-162	88	22	with	with	ADP
admet-162	88	23	the	the	DET
admet-162	88	24	recovery	recovery	NOUN
admet-162	88	25	of	of	ADP
admet-162	88	26	seizures	seizure	NOUN
admet-162	88	27	control	control	VERB
admet-162	89	1	[	[	X
admet-162	89	2	35,36	35,36	NUM
admet-162	89	3	]	]	PUNCT
admet-162	89	4	.	.	PUNCT
admet-162	90	1	it	it	PRON
admet-162	90	2	is	be	AUX
admet-162	90	3	known	know	VERB
admet-162	90	4	that	that	SCONJ
admet-162	90	5	abc	abc	PROPN
admet-162	90	6	-	-	PUNCT
admet-162	90	7	transporters	transporter	NOUN
admet-162	90	8	are	be	AUX
admet-162	90	9	located	locate	VERB
admet-162	90	10	at	at	ADP
admet-162	90	11	the	the	DET
admet-162	90	12	apical	apical	ADJ
admet-162	90	13	membrane	membrane	NOUN
admet-162	90	14	of	of	ADP
admet-162	90	15	both	both	PRON
admet-162	90	16	acinar	acinar	NOUN
admet-162	90	17	and	and	CCONJ
admet-162	90	18	ductal	ductal	ADJ
admet-162	90	19	cells	cell	NOUN
admet-162	90	20	[	[	X
admet-162	90	21	37	37	NUM
admet-162	90	22	]	]	PUNCT
admet-162	90	23	.	.	PUNCT
admet-162	91	1	those	those	DET
admet-162	91	2	proteins	protein	NOUN
admet-162	91	3	are	be	AUX
admet-162	91	4	important	important	ADJ
admet-162	91	5	determinants	determinant	NOUN
admet-162	91	6	of	of	ADP
admet-162	91	7	interindividual	interindividual	ADJ
admet-162	91	8	differences	difference	NOUN
admet-162	91	9	in	in	ADP
admet-162	91	10	intestinal	intestinal	ADJ
admet-162	91	11	absorption	absorption	NOUN
admet-162	91	12	or	or	CCONJ
admet-162	91	13	hepatic	hepatic	ADJ
admet-162	91	14	clearance	clearance	NOUN
admet-162	91	15	,	,	PUNCT
admet-162	91	16	and	and	CCONJ
admet-162	91	17	hence	hence	ADV
admet-162	91	18	plasma	plasma	NOUN
admet-162	91	19	levels	level	NOUN
admet-162	91	20	of	of	ADP
admet-162	91	21	some	some	PRON
admet-162	91	22	if	if	SCONJ
admet-162	91	23	not	not	PART
admet-162	91	24	all	all	DET
admet-162	91	25	aeds	aed	NOUN
admet-162	91	26	.	.	PUNCT
admet-162	92	1	these	these	DET
admet-162	92	2	variations	variation	NOUN
admet-162	92	3	can	can	AUX
admet-162	92	4	also	also	ADV
admet-162	92	5	be	be	AUX
admet-162	92	6	detected	detect	VERB
admet-162	92	7	by	by	ADP
admet-162	92	8	measurement	measurement	NOUN
admet-162	92	9	of	of	ADP
admet-162	92	10	saliva	saliva	NOUN
admet-162	92	11	drug	drug	NOUN
admet-162	92	12	concentration	concentration	NOUN
admet-162	92	13	,	,	PUNCT
admet-162	92	14	and	and	CCONJ
admet-162	92	15	it	it	PRON
admet-162	92	16	is	be	AUX
admet-162	92	17	sensitive	sensitive	ADJ
admet-162	92	18	enough	enough	ADV
admet-162	92	19	for	for	ADP
admet-162	92	20	detecting	detect	VERB
admet-162	92	21	systemic	systemic	ADJ
admet-162	92	22	clearance	clearance	NOUN
admet-162	92	23	changes	change	NOUN
admet-162	92	24	.	.	PUNCT
admet-162	93	1	furthermore	furthermore	ADV
admet-162	93	2	,	,	PUNCT
admet-162	93	3	some	some	DET
admet-162	93	4	aeds	aed	NOUN
admet-162	93	5	would	would	AUX
admet-162	93	6	modify	modify	VERB
admet-162	93	7	their	their	PRON
admet-162	93	8	bioavailability	bioavailability	NOUN
admet-162	93	9	and	and	CCONJ
admet-162	93	10	clearance	clearance	NOUN
admet-162	93	11	by	by	ADP
admet-162	93	12	inducing	induce	VERB
admet-162	93	13	efflux	efflux	NOUN
admet-162	93	14	transporter	transporter	NOUN
admet-162	93	15	throughout	throughout	ADP
admet-162	93	16	chronic	chronic	ADJ
admet-162	93	17	treatments	treatment	NOUN
admet-162	93	18	,	,	PUNCT
admet-162	93	19	from	from	ADP
admet-162	93	20	the	the	DET
admet-162	93	21	first	first	ADJ
admet-162	93	22	dose	dose	NOUN
admet-162	93	23	to	to	ADP
admet-162	93	24	multiple	multiple	ADJ
admet-162	93	25	dose	dose	NOUN
admet-162	93	26	administration	administration	NOUN
admet-162	93	27	and	and	CCONJ
admet-162	93	28	it	it	PRON
admet-162	93	29	can	can	AUX
admet-162	93	30	be	be	AUX
admet-162	93	31	documented	document	VERB
admet-162	93	32	by	by	ADP
admet-162	93	33	saliva	saliva	NOUN
admet-162	93	34	drug	drug	NOUN
admet-162	93	35	concentrations	concentration	NOUN
admet-162	93	36	.	.	PUNCT
admet-162	94	1	it	it	PRON
admet-162	94	2	is	be	AUX
admet-162	94	3	important	important	ADJ
admet-162	94	4	to	to	PART
admet-162	94	5	notice	notice	VERB
admet-162	94	6	the	the	DET
admet-162	94	7	usefulness	usefulness	NOUN
admet-162	94	8	of	of	ADP
admet-162	94	9	salivary	salivary	ADJ
admet-162	94	10	drug	drug	NOUN
admet-162	94	11	concentrations	concentration	NOUN
admet-162	94	12	to	to	PART
admet-162	94	13	determine	determine	VERB
admet-162	94	14	systemic	systemic	ADJ
admet-162	94	15	clearance	clearance	NOUN
admet-162	94	16	in	in	ADP
admet-162	94	17	patients	patient	NOUN
admet-162	94	18	not	not	PART
admet-162	94	19	only	only	ADV
admet-162	94	20	from	from	ADP
admet-162	94	21	a	a	DET
admet-162	94	22	pharmacokinetic	pharmacokinetic	ADJ
admet-162	94	23	point	point	NOUN
admet-162	94	24	of	of	ADP
admet-162	94	25	view	view	NOUN
admet-162	94	26	but	but	CCONJ
admet-162	94	27	also	also	ADV
admet-162	94	28	as	as	SCONJ
admet-162	94	29	new	new	ADJ
admet-162	94	30	index	index	NOUN
admet-162	94	31	to	to	PART
admet-162	94	32	phenotype	phenotype	VERB
admet-162	94	33	epileptic	epileptic	ADJ
admet-162	94	34	patients	patient	NOUN
admet-162	94	35	as	as	ADP
admet-162	94	36	refractory	refractory	NOUN
admet-162	94	37	to	to	ADP
admet-162	94	38	the	the	DET
admet-162	94	39	pharmacological	pharmacological	ADJ
admet-162	94	40	treatment	treatment	NOUN
admet-162	94	41	[	[	X
admet-162	94	42	38	38	NUM
admet-162	94	43	]	]	PUNCT
admet-162	94	44	.	.	PUNCT
admet-162	95	1	iannetti	iannetti	PROPN
admet-162	95	2	et	et	PROPN
admet-162	95	3	al	al	PROPN
admet-162	95	4	.	.	PUNCT
admet-162	96	1	[	[	X
admet-162	96	2	39	39	NUM
admet-162	96	3	]	]	PUNCT
admet-162	96	4	recently	recently	ADV
admet-162	96	5	described	describe	VERB
admet-162	96	6	11	11	NUM
admet-162	96	7	-	-	PUNCT
admet-162	96	8	years	year	NOUN
admet-162	96	9	-	-	PUNCT
admet-162	96	10	old	old	ADJ
admet-162	96	11	boy	boy	NOUN
admet-162	96	12	who	who	PRON
admet-162	96	13	developed	develop	VERB
admet-162	96	14	status	status	NOUN
admet-162	96	15	epilepticus	epilepticus	NOUN
admet-162	96	16	,	,	PUNCT
admet-162	96	17	after	after	ADP
admet-162	96	18	a	a	DET
admet-162	96	19	prolonged	prolonged	ADJ
admet-162	96	20	right	right	ADJ
admet-162	96	21	-	-	PUNCT
admet-162	96	22	side	side	NOUN
admet-162	96	23	simple	simple	ADJ
admet-162	96	24	partial	partial	ADJ
admet-162	96	25	motor	motor	NOUN
admet-162	96	26	seizure	seizure	NOUN
admet-162	96	27	,	,	PUNCT
admet-162	96	28	which	which	PRON
admet-162	96	29	was	be	AUX
admet-162	96	30	unresponsive	unresponsive	ADJ
admet-162	96	31	to	to	ADP
admet-162	96	32	long	long	ADJ
admet-162	96	33	term	term	NOUN
admet-162	96	34	aggressive	aggressive	ADJ
admet-162	96	35	treatment	treatment	NOUN
admet-162	96	36	with	with	ADP
admet-162	96	37	several	several	ADJ
admet-162	96	38	aeds	aed	NOUN
admet-162	96	39	.	.	PUNCT
admet-162	97	1	control	control	NOUN
admet-162	97	2	of	of	ADP
admet-162	97	3	convulsive	convulsive	ADJ
admet-162	97	4	seizures	seizure	NOUN
admet-162	97	5	was	be	AUX
admet-162	97	6	achieved	achieve	VERB
admet-162	97	7	at	at	ADP
admet-162	97	8	valproic	valproic	ADJ
admet-162	97	9	acid	acid	NOUN
admet-162	97	10	plasma	plasma	NOUN
admet-162	97	11	level	level	NOUN
admet-162	97	12	of	of	ADP
admet-162	97	13	108	108	NUM
admet-162	97	14	μg	μg	NOUN
admet-162	97	15	/	/	SYM
admet-162	97	16	ml	ml	PROPN
admet-162	97	17	,	,	PUNCT
admet-162	97	18	but	but	CCONJ
admet-162	97	19	electrical	electrical	ADJ
admet-162	97	20	status	status	NOUN
admet-162	97	21	epilepticus	epilepticus	NOUN
admet-162	97	22	persisted	persist	VERB
admet-162	97	23	,	,	PUNCT
admet-162	97	24	and	and	CCONJ
admet-162	97	25	the	the	DET
admet-162	97	26	child	child	NOUN
admet-162	97	27	remained	remain	VERB
admet-162	97	28	comatose	comatose	ADJ
admet-162	97	29	.	.	PUNCT
admet-162	98	1	on	on	ADP
admet-162	98	2	day	day	NOUN
admet-162	98	3	37	37	NUM
admet-162	98	4	,	,	PUNCT
admet-162	98	5	a	a	DET
admet-162	98	6	treatment	treatment	NOUN
admet-162	98	7	with	with	ADP
admet-162	98	8	verapamil	verapamil	NOUN
admet-162	98	9	(	(	PUNCT
admet-162	98	10	blocker	blocker	NOUN
admet-162	98	11	of	of	ADP
admet-162	98	12	calcium	calcium	NOUN
admet-162	98	13	l	l	NOUN
admet-162	98	14	-	-	NOUN
admet-162	98	15	channel	channel	NOUN
admet-162	98	16	and	and	CCONJ
admet-162	98	17	p	p	NOUN
admet-162	98	18	-	-	PUNCT
admet-162	98	19	gp	gp	NOUN
admet-162	98	20	)	)	PUNCT
admet-162	98	21	was	be	AUX
admet-162	98	22	started	start	VERB
admet-162	98	23	and	and	CCONJ
admet-162	98	24	1.5	1.5	NUM
admet-162	98	25	hour	hour	NOUN
admet-162	98	26	after	after	ADP
admet-162	98	27	the	the	DET
admet-162	98	28	initiation	initiation	NOUN
admet-162	98	29	the	the	DET
admet-162	98	30	infusion	infusion	NOUN
admet-162	98	31	,	,	PUNCT
admet-162	98	32	the	the	DET
admet-162	98	33	patient	patient	NOUN
admet-162	98	34	regained	regain	VERB
admet-162	98	35	consciousness	consciousness	NOUN
admet-162	98	36	,	,	PUNCT
admet-162	98	37	was	be	AUX
admet-162	98	38	able	able	ADJ
admet-162	98	39	to	to	PART
admet-162	98	40	breathe	breathe	VERB
admet-162	98	41	spontaneously	spontaneously	ADV
admet-162	98	42	,	,	PUNCT
admet-162	98	43	and	and	CCONJ
admet-162	98	44	the	the	DET
admet-162	98	45	status	status	NOUN
admet-162	98	46	epilepticus	epilepticus	VERB
admet-162	98	47	,	,	PUNCT
admet-162	98	48	promptly	promptly	ADV
admet-162	98	49	disappeared	disappear	VERB
admet-162	98	50	.	.	PUNCT
admet-162	99	1	the	the	DET
admet-162	99	2	authors	author	NOUN
admet-162	99	3	suggested	suggest	VERB
admet-162	99	4	that	that	SCONJ
admet-162	99	5	verapamil	verapamil	NOUN
admet-162	99	6	,	,	PUNCT
admet-162	99	7	a	a	DET
admet-162	99	8	known	know	VERB
admet-162	99	9	p	p	NOUN
admet-162	99	10	-	-	PUNCT
admet-162	99	11	gp	gp	NOUN
admet-162	99	12	inhibitor	inhibitor	NOUN
admet-162	99	13	acted	act	VERB
admet-162	99	14	by	by	ADP
admet-162	99	15	facilitating	facilitate	VERB
admet-162	99	16	the	the	DET
admet-162	99	17	brain	brain	NOUN
admet-162	99	18	penetration	penetration	NOUN
admet-162	99	19	of	of	ADP
admet-162	99	20	aeds	aed	NOUN
admet-162	99	21	simultaneously	simultaneously	ADV
admet-162	99	22	administrated	administrate	VERB
admet-162	99	23	to	to	ADP
admet-162	99	24	the	the	DET
admet-162	99	25	patient	patient	NOUN
admet-162	99	26	.	.	PUNCT
admet-162	100	1	role	role	NOUN
admet-162	100	2	of	of	ADP
admet-162	100	3	p	p	NOUN
admet-162	100	4	-	-	PUNCT
admet-162	100	5	glycoprotein	glycoprotein	NOUN
admet-162	100	6	in	in	ADP
admet-162	100	7	epileptogenesis	epileptogenesis	NOUN
admet-162	100	8	taking	take	VERB
admet-162	100	9	in	in	ADP
admet-162	100	10	account	account	NOUN
admet-162	100	11	that	that	SCONJ
admet-162	100	12	in	in	ADP
admet-162	100	13	a	a	DET
admet-162	100	14	normal	normal	ADJ
admet-162	100	15	brain	brain	NOUN
admet-162	100	16	,	,	PUNCT
admet-162	100	17	neurons	neuron	NOUN
admet-162	100	18	do	do	AUX
admet-162	100	19	not	not	PART
admet-162	100	20	express	express	VERB
admet-162	100	21	p	p	NOUN
admet-162	100	22	-	-	PUNCT
admet-162	100	23	gp	gp	NOUN
admet-162	100	24	,	,	PUNCT
admet-162	100	25	which	which	PRON
admet-162	100	26	could	could	AUX
admet-162	100	27	be	be	AUX
admet-162	100	28	the	the	DET
admet-162	100	29	functional	functional	ADJ
admet-162	100	30	changes	change	NOUN
admet-162	100	31	in	in	ADP
admet-162	100	32	neurons	neuron	NOUN
admet-162	100	33	expressing	express	VERB
admet-162	100	34	p	p	NOUN
admet-162	100	35	-	-	PUNCT
admet-162	100	36	gp	gp	NOUN
admet-162	100	37	,	,	PUNCT
admet-162	100	38	?	?	PUNCT
admet-162	101	1	approximately	approximately	ADV
admet-162	101	2	one	one	NUM
admet-162	101	3	third	third	NOUN
admet-162	101	4	of	of	ADP
admet-162	101	5	patients	patient	NOUN
admet-162	101	6	with	with	ADP
admet-162	101	7	epilepsy	epilepsy	NOUN
admet-162	101	8	do	do	AUX
admet-162	101	9	not	not	PART
admet-162	101	10	have	have	VERB
admet-162	101	11	satisfactory	satisfactory	ADJ
admet-162	101	12	control	control	NOUN
admet-162	101	13	of	of	ADP
admet-162	101	14	seizures	seizure	NOUN
admet-162	101	15	with	with	ADP
admet-162	101	16	antiepileptic	antiepileptic	ADJ
admet-162	101	17	drugs	drug	NOUN
admet-162	101	18	(	(	PUNCT
admet-162	101	19	aeds	aed	NOUN
admet-162	101	20	)	)	PUNCT
admet-162	101	21	and	and	CCONJ
admet-162	101	22	it	it	PRON
admet-162	101	23	is	be	AUX
admet-162	101	24	suggested	suggest	VERB
admet-162	101	25	that	that	SCONJ
admet-162	101	26	drug	drug	NOUN
admet-162	101	27	resistant	resistant	ADJ
admet-162	101	28	phenotype	phenotype	NOUN
admet-162	101	29	could	could	AUX
admet-162	101	30	be	be	AUX
admet-162	101	31	present	present	ADJ
admet-162	101	32	at	at	ADP
admet-162	101	33	the	the	DET
admet-162	101	34	early	early	ADJ
admet-162	101	35	stage	stage	NOUN
admet-162	101	36	of	of	ADP
admet-162	101	37	the	the	DET
admet-162	101	38	disease	disease	NOUN
admet-162	101	39	[	[	X
admet-162	101	40	40	40	NUM
admet-162	101	41	]	]	PUNCT
admet-162	101	42	.	.	PUNCT
admet-162	102	1	at	at	ADP
admet-162	102	2	present	present	ADJ
admet-162	102	3	,	,	PUNCT
admet-162	102	4	antiepileptic	antiepileptic	ADJ
admet-162	102	5	drug	drug	NOUN
admet-162	102	6	refractoriness	refractoriness	NOUN
admet-162	102	7	has	have	AUX
admet-162	102	8	been	be	AUX
admet-162	102	9	explained	explain	VERB
admet-162	102	10	by	by	ADP
admet-162	102	11	the	the	DET
admet-162	102	12	“	"	PUNCT
admet-162	102	13	reduced	reduce	VERB
admet-162	102	14	drug	drug	NOUN
admet-162	102	15	-	-	PUNCT
admet-162	102	16	target	target	NOUN
admet-162	102	17	sensitivity	sensitivity	NOUN
admet-162	102	18	”	"	PUNCT
admet-162	102	19	and	and	CCONJ
admet-162	102	20	the	the	DET
admet-162	102	21	“	"	PUNCT
admet-162	102	22	drug	drug	NOUN
admet-162	102	23	transporter	transporter	NOUN
admet-162	102	24	overexpression	overexpression	NOUN
admet-162	102	25	”	"	PUNCT
admet-162	102	26	hypotheses	hypothesis	NOUN
admet-162	102	27	.	.	PUNCT
admet-162	103	1	mdr-1	mdr-1	NUM
admet-162	103	2	gene	gene	NOUN
admet-162	103	3	upregulation	upregulation	NOUN
admet-162	103	4	could	could	AUX
admet-162	103	5	be	be	AUX
admet-162	103	6	acquired	acquire	VERB
admet-162	103	7	as	as	ADP
admet-162	103	8	a	a	DET
admet-162	103	9	consequence	consequence	NOUN
admet-162	103	10	of	of	ADP
admet-162	103	11	repetitive	repetitive	ADJ
admet-162	103	12	non	non	ADJ
admet-162	103	13	-	-	ADJ
admet-162	103	14	controlled	control	VERB
admet-162	103	15	seizures	seizure	NOUN
admet-162	103	16	[	[	X
admet-162	103	17	28,29	28,29	X
admet-162	103	18	]	]	PUNCT
admet-162	103	19	as	as	ADV
admet-162	103	20	well	well	ADV
admet-162	103	21	as	as	ADP
admet-162	103	22	secondary	secondary	ADJ
admet-162	103	23	to	to	ADP
admet-162	103	24	pathological	pathological	ADJ
admet-162	103	25	conditions	condition	NOUN
admet-162	103	26	such	such	ADJ
admet-162	103	27	as	as	ADP
admet-162	103	28	inflammation	inflammation	NOUN
admet-162	103	29	,	,	PUNCT
admet-162	103	30	tumors	tumor	NOUN
admet-162	103	31	or	or	CCONJ
admet-162	103	32	hypoxia	hypoxia	NOUN
admet-162	103	33	[	[	PUNCT
admet-162	103	34	41	41	NUM
admet-162	103	35	-	-	SYM
admet-162	103	36	44	44	NUM
admet-162	103	37	]	]	PUNCT
admet-162	103	38	,	,	PUNCT
admet-162	103	39	supporting	support	VERB
admet-162	103	40	the	the	DET
admet-162	103	41	idea	idea	NOUN
admet-162	103	42	that	that	SCONJ
admet-162	103	43	silent	silent	ADJ
admet-162	103	44	mechanisms	mechanism	NOUN
admet-162	103	45	could	could	AUX
admet-162	103	46	overexpress	overexpress	VERB
admet-162	103	47	p	p	NOUN
admet-162	103	48	-	-	PUNCT
admet-162	103	49	gp	gp	NOUN
admet-162	103	50	in	in	ADP
admet-162	103	51	brain	brain	NOUN
admet-162	103	52	before	before	ADP
admet-162	103	53	epilepsy	epilepsy	NOUN
admet-162	103	54	and	and	CCONJ
admet-162	103	55	refractoriness	refractoriness	NOUN
admet-162	103	56	becomes	become	VERB
admet-162	103	57	clinically	clinically	ADV
admet-162	103	58	evident	evident	ADJ
admet-162	103	59	.	.	PUNCT
admet-162	104	1	repetitive	repetitive	ADJ
admet-162	104	2	seizures	seizure	NOUN
admet-162	104	3	,	,	PUNCT
admet-162	104	4	status	status	NOUN
admet-162	104	5	epilepticus	epilepticus	VERB
admet-162	104	6	as	as	ADV
admet-162	104	7	well	well	ADV
admet-162	104	8	as	as	ADP
admet-162	104	9	brain	brain	NOUN
admet-162	104	10	hypoxia	hypoxia	NOUN
admet-162	104	11	induces	induce	VERB
admet-162	104	12	p	p	NOUN
admet-162	104	13	-	-	PUNCT
admet-162	104	14	gp	gp	NOUN
admet-162	104	15	expression	expression	NOUN
admet-162	104	16	in	in	ADP
admet-162	104	17	neurons	neuron	NOUN
admet-162	104	18	.	.	PUNCT
admet-162	105	1	this	this	DET
admet-162	105	2	p	p	NOUN
admet-162	105	3	-	-	PUNCT
admet-162	105	4	gp	gp	NOUN
admet-162	105	5	induced	induce	VERB
admet-162	105	6	expression	expression	NOUN
admet-162	105	7	depends	depend	VERB
admet-162	105	8	on	on	ADP
admet-162	105	9	the	the	DET
admet-162	105	10	frequency	frequency	NOUN
admet-162	105	11	and	and	CCONJ
admet-162	105	12	intensity	intensity	NOUN
admet-162	105	13	of	of	ADP
admet-162	105	14	seizures	seizure	NOUN
admet-162	105	15	and	and	CCONJ
admet-162	105	16	is	be	AUX
admet-162	105	17	related	relate	VERB
admet-162	105	18	to	to	ADP
admet-162	105	19	a	a	DET
admet-162	105	20	progressive	progressive	ADJ
admet-162	105	21	increase	increase	NOUN
admet-162	105	22	of	of	ADP
admet-162	105	23	the	the	DET
admet-162	105	24	pharmacoresistant	pharmacoresistant	ADJ
admet-162	105	25	phenotype	phenotype	NOUN
admet-162	105	26	[	[	X
admet-162	105	27	45	45	NUM
admet-162	105	28	]	]	PUNCT
admet-162	105	29	.	.	PUNCT
admet-162	106	1	furthermore	furthermore	ADV
admet-162	106	2	,	,	PUNCT
admet-162	106	3	the	the	DET
admet-162	106	4	induced	induced	ADJ
admet-162	106	5	“	"	PUNCT
admet-162	106	6	de	de	X
admet-162	106	7	novo	novo	NOUN
admet-162	106	8	”	"	PUNCT
admet-162	106	9	expression	expression	NOUN
admet-162	106	10	of	of	ADP
admet-162	106	11	p	p	NOUN
admet-162	106	12	-	-	PUNCT
admet-162	106	13	gp	gp	NOUN
admet-162	106	14	in	in	ADP
admet-162	106	15	previously	previously	ADV
admet-162	106	16	non	non	ADJ
admet-162	106	17	-	-	ADJ
admet-162	106	18	expressive	expressive	ADJ
admet-162	106	19	cells	cell	NOUN
admet-162	106	20	as	as	SCONJ
admet-162	106	21	observed	observe	VERB
admet-162	106	22	particularly	particularly	ADV
admet-162	106	23	in	in	ADP
admet-162	106	24	lazarowski	lazarowski	PROPN
admet-162	106	25	et	et	PROPN
admet-162	106	26	al	al	PROPN
admet-162	106	27	.	.	PROPN
admet-162	106	28	admet	admet	PROPN
admet-162	106	29	&	&	CCONJ
admet-162	106	30	dmpk	dmpk	PROPN
admet-162	106	31	3(2	3(2	NUM
admet-162	106	32	)	)	PUNCT
admet-162	106	33	(	(	PUNCT
admet-162	106	34	2015	2015	NUM
admet-162	106	35	)	)	PUNCT
admet-162	106	36	110	110	NUM
admet-162	106	37	-	-	SYM
admet-162	106	38	121	121	NUM
admet-162	106	39	116	116	NUM
admet-162	106	40	neurons	neuron	NOUN
admet-162	106	41	from	from	ADP
admet-162	106	42	epileptogenic	epileptogenic	ADJ
admet-162	106	43	brain	brain	NOUN
admet-162	106	44	areas	area	NOUN
admet-162	106	45	,	,	PUNCT
admet-162	106	46	suggests	suggest	VERB
admet-162	106	47	a	a	DET
admet-162	106	48	differential	differential	ADJ
admet-162	106	49	role	role	NOUN
admet-162	106	50	of	of	ADP
admet-162	106	51	this	this	DET
admet-162	106	52	transporter	transporter	NOUN
admet-162	106	53	,	,	PUNCT
admet-162	106	54	perhaps	perhaps	ADV
admet-162	106	55	related	relate	VERB
admet-162	106	56	to	to	ADP
admet-162	106	57	the	the	DET
admet-162	106	58	intrinsic	intrinsic	ADJ
admet-162	106	59	convulsive	convulsive	ADJ
admet-162	106	60	mechanism	mechanism	NOUN
admet-162	106	61	[	[	X
admet-162	106	62	29,33,46	29,33,46	NUM
admet-162	106	63	]	]	X
admet-162	106	64	.	.	PUNCT
admet-162	107	1	in	in	ADP
admet-162	107	2	this	this	DET
admet-162	107	3	regard	regard	NOUN
admet-162	107	4	,	,	PUNCT
admet-162	107	5	a	a	DET
admet-162	107	6	group	group	NOUN
admet-162	107	7	of	of	ADP
admet-162	107	8	evidence	evidence	NOUN
admet-162	107	9	indicates	indicate	VERB
admet-162	107	10	that	that	SCONJ
admet-162	107	11	p	p	X
admet-162	107	12	-	-	PUNCT
admet-162	107	13	gp	gp	NOUN
admet-162	107	14	can	can	AUX
admet-162	107	15	also	also	ADV
admet-162	107	16	decrease	decrease	VERB
admet-162	107	17	the	the	DET
admet-162	107	18	plasma	plasma	NOUN
admet-162	107	19	membrane	membrane	NOUN
admet-162	107	20	potential	potential	NOUN
admet-162	107	21	of	of	ADP
admet-162	107	22	several	several	ADJ
admet-162	107	23	cell	cell	NOUN
admet-162	107	24	types	type	NOUN
admet-162	108	1	[	[	X
admet-162	108	2	47,48	47,48	NOUN
admet-162	108	3	]	]	PUNCT
admet-162	108	4	and	and	CCONJ
admet-162	108	5	modify	modify	VERB
admet-162	108	6	swelling	swelling	NOUN
admet-162	108	7	-	-	PUNCT
admet-162	108	8	activated	activate	VERB
admet-162	108	9	cl	cl	NOUN
admet-162	108	10	−	−	NOUN
admet-162	108	11	currents	current	NOUN
admet-162	109	1	[	[	X
admet-162	109	2	49	49	NUM
admet-162	109	3	]	]	PUNCT
admet-162	109	4	,	,	PUNCT
admet-162	110	1	both	both	DET
admet-162	110	2	physiologic	physiologic	ADJ
admet-162	110	3	disturbances	disturbance	NOUN
admet-162	110	4	observed	observe	VERB
admet-162	110	5	during	during	ADP
admet-162	110	6	brain	brain	NOUN
admet-162	110	7	hypoxia	hypoxia	NOUN
admet-162	110	8	[	[	X
admet-162	110	9	50	50	NUM
admet-162	110	10	]	]	PUNCT
admet-162	110	11	and	and	CCONJ
admet-162	110	12	convulsive	convulsive	ADJ
admet-162	110	13	stress	stress	NOUN
admet-162	110	14	[	[	X
admet-162	110	15	51	51	NUM
admet-162	110	16	]	]	PUNCT
admet-162	110	17	.	.	PUNCT
admet-162	111	1	according	accord	VERB
admet-162	111	2	to	to	ADP
admet-162	111	3	these	these	DET
admet-162	111	4	observation	observation	NOUN
admet-162	111	5	,	,	PUNCT
admet-162	111	6	recently	recently	ADV
admet-162	111	7	was	be	AUX
admet-162	111	8	reported	report	VERB
admet-162	111	9	the	the	DET
admet-162	111	10	first	first	ADJ
admet-162	111	11	study	study	NOUN
admet-162	111	12	demonstrating	demonstrate	VERB
admet-162	111	13	that	that	SCONJ
admet-162	111	14	daily	daily	ADJ
admet-162	111	15	ptz	ptz	VERB
admet-162	111	16	-	-	PUNCT
admet-162	111	17	induced	induce	VERB
admet-162	111	18	seizures	seizure	NOUN
admet-162	111	19	produces	produce	VERB
admet-162	111	20	simultaneously	simultaneously	ADV
admet-162	111	21	the	the	DET
admet-162	111	22	progressive	progressive	ADJ
admet-162	111	23	acquisition	acquisition	NOUN
admet-162	111	24	of	of	ADP
admet-162	111	25	pharmacoresistant	pharmacoresistant	ADJ
admet-162	111	26	phenotype	phenotype	NOUN
admet-162	111	27	,	,	PUNCT
admet-162	111	28	increased	increase	VERB
admet-162	111	29	brain	brain	NOUN
admet-162	111	30	p	p	NOUN
admet-162	111	31	-	-	PUNCT
admet-162	111	32	gp	gp	NOUN
admet-162	111	33	expression	expression	NOUN
admet-162	111	34	and	and	CCONJ
admet-162	111	35	high	high	ADJ
admet-162	111	36	membrane	membrane	NOUN
admet-162	111	37	depolarization	depolarization	NOUN
admet-162	111	38	in	in	ADP
admet-162	111	39	brain	brain	NOUN
admet-162	111	40	areas	area	NOUN
admet-162	111	41	such	such	ADJ
admet-162	111	42	as	as	ADP
admet-162	111	43	hippocampus	hippocampus	NOUN
admet-162	111	44	and	and	CCONJ
admet-162	111	45	cortex	cortex	NOUN
admet-162	111	46	[	[	X
admet-162	111	47	52	52	NUM
admet-162	111	48	]	]	PUNCT
admet-162	111	49	.	.	PUNCT
admet-162	112	1	in	in	ADP
admet-162	112	2	this	this	DET
admet-162	112	3	study	study	NOUN
admet-162	112	4	,	,	PUNCT
admet-162	112	5	the	the	DET
admet-162	112	6	recovery	recovery	NOUN
admet-162	112	7	of	of	ADP
admet-162	112	8	potential	potential	ADJ
admet-162	112	9	membrane	membrane	NOUN
admet-162	112	10	of	of	ADP
admet-162	112	11	depolarized	depolarized	ADJ
admet-162	112	12	slides	slide	NOUN
admet-162	112	13	in	in	ADP
admet-162	112	14	hippocampus	hippocampus	NOUN
admet-162	112	15	and	and	CCONJ
admet-162	112	16	neocotex	neocotex	NOUN
admet-162	112	17	(	(	PUNCT
admet-162	112	18	in	in	ADP
admet-162	112	19	vitro	vitro	X
admet-162	112	20	experiments	experiment	NOUN
admet-162	112	21	)	)	PUNCT
admet-162	112	22	was	be	AUX
admet-162	112	23	induced	induce	VERB
admet-162	112	24	when	when	SCONJ
admet-162	112	25	pht	pht	PROPN
admet-162	112	26	was	be	AUX
admet-162	112	27	combined	combine	VERB
admet-162	112	28	with	with	ADP
admet-162	112	29	nimodipine	nimodipine	NOUN
admet-162	112	30	,	,	PUNCT
admet-162	112	31	a	a	DET
admet-162	112	32	calcium	calcium	NOUN
admet-162	112	33	channel	channel	NOUN
admet-162	112	34	blocker	blocker	NOUN
admet-162	112	35	that	that	PRON
admet-162	112	36	also	also	ADV
admet-162	112	37	inhibit	inhibit	VERB
admet-162	112	38	p	p	NOUN
admet-162	112	39	-	-	PUNCT
admet-162	112	40	gp	gp	NOUN
admet-162	112	41	function	function	NOUN
admet-162	112	42	.	.	PUNCT
admet-162	113	1	in	in	ADP
admet-162	113	2	addition	addition	NOUN
admet-162	113	3	to	to	ADP
admet-162	113	4	the	the	DET
admet-162	113	5	much	much	ADV
admet-162	113	6	known	know	VERB
admet-162	113	7	drug	drug	NOUN
admet-162	113	8	pump	pump	NOUN
admet-162	113	9	model	model	NOUN
admet-162	113	10	,	,	PUNCT
admet-162	113	11	some	some	DET
admet-162	113	12	studies	study	NOUN
admet-162	113	13	indicate	indicate	VERB
admet-162	113	14	that	that	SCONJ
admet-162	113	15	p	p	X
admet-162	113	16	-	-	PUNCT
admet-162	113	17	gp	gp	NOUN
admet-162	113	18	may	may	AUX
admet-162	113	19	mediate	mediate	VERB
admet-162	113	20	drug	drug	NOUN
admet-162	113	21	resistance	resistance	NOUN
admet-162	113	22	through	through	ADP
admet-162	113	23	channels	channel	NOUN
admet-162	113	24	function	function	VERB
admet-162	113	25	regulation	regulation	NOUN
admet-162	113	26	[	[	X
admet-162	113	27	53	53	NUM
admet-162	113	28	]	]	PUNCT
admet-162	113	29	.	.	PUNCT
admet-162	114	1	supporting	support	VERB
admet-162	114	2	this	this	DET
admet-162	114	3	idea	idea	NOUN
admet-162	114	4	,	,	PUNCT
admet-162	114	5	it	it	PRON
admet-162	114	6	has	have	AUX
admet-162	114	7	been	be	AUX
admet-162	114	8	described	describe	VERB
admet-162	114	9	that	that	SCONJ
admet-162	114	10	mdr1	mdr1	PROPN
admet-162	114	11	protein	protein	NOUN
admet-162	114	12	behaves	behave	VERB
admet-162	114	13	as	as	ADP
admet-162	114	14	some	some	DET
admet-162	114	15	type	type	NOUN
admet-162	114	16	of	of	ADP
admet-162	114	17	cltransporter	cltransporter	NOUN
admet-162	114	18	,	,	PUNCT
admet-162	114	19	stimulates	stimulate	VERB
admet-162	114	20	clchannel	clchannel	NOUN
admet-162	114	21	activity	activity	NOUN
admet-162	114	22	and	and	CCONJ
admet-162	114	23	may	may	AUX
admet-162	114	24	alter	alter	VERB
admet-162	114	25	cell	cell	NOUN
admet-162	114	26	volume	volume	NOUN
admet-162	114	27	in	in	ADP
admet-162	114	28	several	several	ADJ
admet-162	114	29	cell	cell	NOUN
admet-162	114	30	types	type	NOUN
admet-162	115	1	[	[	X
admet-162	115	2	54	54	NUM
admet-162	115	3	]	]	PUNCT
admet-162	115	4	.	.	PUNCT
admet-162	116	1	its	its	PRON
admet-162	116	2	overexpression	overexpression	NOUN
admet-162	116	3	leads	lead	VERB
admet-162	116	4	to	to	ADP
admet-162	116	5	decreased	decrease	VERB
admet-162	116	6	plasma	plasma	NOUN
admet-162	116	7	membrane	membrane	NOUN
admet-162	116	8	electrical	electrical	ADJ
admet-162	116	9	potential	potential	NOUN
admet-162	116	10	by	by	ADP
admet-162	116	11	increasing	increase	VERB
admet-162	116	12	cl	cl	NOUN
admet-162	116	13	permeability	permeability	NOUN
admet-162	116	14	and	and	CCONJ
admet-162	116	15	thus	thus	ADV
admet-162	116	16	decreasing	decrease	VERB
admet-162	116	17	the	the	DET
admet-162	116	18	dominance	dominance	NOUN
admet-162	116	19	of	of	ADP
admet-162	116	20	membrane	membrane	NOUN
admet-162	116	21	potential	potential	NOUN
admet-162	116	22	by	by	ADP
admet-162	116	23	k	k	PROPN
admet-162	116	24	+	+	NOUN
admet-162	116	25	conductance	conductance	NOUN
admet-162	116	26	,	,	PUNCT
admet-162	116	27	and	and	CCONJ
admet-162	116	28	leads	lead	VERB
admet-162	116	29	to	to	PART
admet-162	116	30	altered	alter	VERB
admet-162	116	31	phi	phi	NOUN
admet-162	116	32	regulation	regulation	NOUN
admet-162	116	33	[	[	X
admet-162	116	34	47,48	47,48	NOUN
admet-162	116	35	]	]	X
admet-162	116	36	.	.	PUNCT
admet-162	117	1	so	so	ADV
admet-162	117	2	,	,	PUNCT
admet-162	117	3	brain	brain	NOUN
admet-162	117	4	p	p	NOUN
admet-162	117	5	-	-	PUNCT
admet-162	117	6	gp	gp	NOUN
admet-162	117	7	overexpression	overexpression	NOUN
admet-162	117	8	could	could	AUX
admet-162	117	9	contribute	contribute	VERB
admet-162	117	10	to	to	ADP
admet-162	117	11	crucial	crucial	ADJ
admet-162	117	12	factors	factor	NOUN
admet-162	117	13	detected	detect	VERB
admet-162	117	14	in	in	ADP
admet-162	117	15	several	several	ADJ
admet-162	117	16	types	type	NOUN
admet-162	117	17	of	of	ADP
admet-162	117	18	epilepsy	epilepsy	NOUN
admet-162	117	19	such	such	ADJ
admet-162	117	20	as	as	ADP
admet-162	117	21	the	the	DET
admet-162	117	22	intracellular	intracellular	ADJ
admet-162	117	23	acidosis	acidosis	NOUN
admet-162	117	24	associated	associate	VERB
admet-162	117	25	with	with	ADP
admet-162	117	26	altered	alter	VERB
admet-162	117	27	na	na	ADP
admet-162	117	28	+	+	CCONJ
admet-162	117	29	/h	/h	SYM
admet-162	117	30	+	+	NUM
admet-162	117	31	exchange	exchange	NOUN
admet-162	117	32	[	[	X
admet-162	117	33	55	55	NUM
admet-162	117	34	]	]	PUNCT
admet-162	117	35	,	,	PUNCT
admet-162	117	36	enhanced	enhance	VERB
admet-162	117	37	extracellular	extracellular	ADJ
admet-162	117	38	concentration	concentration	NOUN
admet-162	117	39	of	of	ADP
admet-162	117	40	potassium	potassium	NOUN
admet-162	117	41	[	[	X
admet-162	117	42	56	56	NUM
admet-162	117	43	]	]	PUNCT
admet-162	117	44	,	,	PUNCT
admet-162	117	45	and	and	CCONJ
admet-162	117	46	particularly	particularly	ADV
admet-162	117	47	in	in	ADP
admet-162	117	48	the	the	DET
admet-162	117	49	increased	increase	VERB
admet-162	117	50	membrane	membrane	NOUN
admet-162	117	51	depolarization	depolarization	NOUN
admet-162	117	52	[	[	X
admet-162	117	53	57	57	NUM
admet-162	117	54	]	]	PUNCT
admet-162	117	55	.	.	PUNCT
admet-162	118	1	considering	consider	VERB
admet-162	118	2	all	all	DET
admet-162	118	3	the	the	DET
admet-162	118	4	mentioned	mention	VERB
admet-162	118	5	evidences	evidence	NOUN
admet-162	118	6	,	,	PUNCT
admet-162	118	7	the	the	DET
admet-162	118	8	popular	popular	ADJ
admet-162	118	9	comments	comment	NOUN
admet-162	118	10	saying	say	VERB
admet-162	118	11	that	that	SCONJ
admet-162	118	12	“	"	PUNCT
admet-162	118	13	seizures	seizure	NOUN
admet-162	118	14	induce	induce	VERB
admet-162	118	15	seizures	seizure	NOUN
admet-162	118	16	”	"	PUNCT
admet-162	118	17	and	and	CCONJ
admet-162	118	18	“	"	PUNCT
admet-162	118	19	seizures	seizure	NOUN
admet-162	118	20	without	without	ADP
admet-162	118	21	control	control	NOUN
admet-162	118	22	induce	induce	VERB
admet-162	118	23	refractoriness	refractoriness	NOUN
admet-162	118	24	”	"	PUNCT
admet-162	118	25	could	could	AUX
admet-162	118	26	have	have	VERB
admet-162	118	27	a	a	DET
admet-162	118	28	mechanistic	mechanistic	ADJ
admet-162	118	29	and	and	CCONJ
admet-162	118	30	molecular	molecular	ADJ
admet-162	118	31	explanation	explanation	NOUN
admet-162	118	32	,	,	PUNCT
admet-162	118	33	where	where	SCONJ
admet-162	118	34	progressive	progressive	ADJ
admet-162	118	35	and	and	CCONJ
admet-162	118	36	induced	induce	VERB
admet-162	118	37	p	p	NOUN
admet-162	118	38	-	-	PUNCT
admet-162	118	39	gp	gp	NOUN
admet-162	118	40	expression	expression	NOUN
admet-162	118	41	in	in	ADP
admet-162	118	42	neurons	neuron	NOUN
admet-162	118	43	reduces	reduce	VERB
admet-162	118	44	the	the	DET
admet-162	118	45	membrane	membrane	NOUN
admet-162	118	46	potential	potential	NOUN
admet-162	118	47	and	and	CCONJ
admet-162	118	48	the	the	DET
admet-162	118	49	seizure	seizure	NOUN
admet-162	118	50	thresholds	threshold	NOUN
admet-162	118	51	,	,	PUNCT
admet-162	118	52	and	and	CCONJ
admet-162	118	53	increasing	increase	VERB
admet-162	118	54	the	the	DET
admet-162	118	55	risk	risk	NOUN
admet-162	118	56	of	of	ADP
admet-162	118	57	pharmacoressitance	pharmacoressitance	NOUN
admet-162	118	58	.	.	PUNCT
admet-162	119	1	consequently	consequently	ADV
admet-162	119	2	,	,	PUNCT
admet-162	119	3	how	how	SCONJ
admet-162	119	4	much	much	ADJ
admet-162	119	5	time	time	NOUN
admet-162	119	6	p	p	X
admet-162	119	7	-	-	PUNCT
admet-162	119	8	gp	gp	NOUN
admet-162	119	9	can	can	AUX
admet-162	119	10	be	be	AUX
admet-162	119	11	expressed	express	VERB
admet-162	119	12	in	in	ADP
admet-162	119	13	brain	brain	NOUN
admet-162	119	14	cells	cell	NOUN
admet-162	119	15	after	after	ADP
admet-162	119	16	an	an	DET
admet-162	119	17	initial	initial	ADJ
admet-162	119	18	inducer	inducer	NOUN
admet-162	119	19	insult	insult	NOUN
admet-162	119	20	?	?	PUNCT
admet-162	120	1	figure	figure	NOUN
admet-162	120	2	3	3	NUM
admet-162	120	3	:	:	PUNCT
admet-162	120	4	neuronal	neuronal	ADJ
admet-162	120	5	expression	expression	NOUN
admet-162	120	6	of	of	ADP
admet-162	120	7	p	p	NOUN
admet-162	120	8	-	-	PUNCT
admet-162	120	9	gp	gp	NOUN
admet-162	120	10	(	(	PUNCT
admet-162	120	11	white	white	ADJ
admet-162	120	12	arrow	arrow	NOUN
admet-162	120	13	)	)	PUNCT
admet-162	120	14	can	can	AUX
admet-162	120	15	be	be	AUX
admet-162	120	16	induced	induce	VERB
admet-162	120	17	by	by	ADP
admet-162	120	18	seizures	seizure	NOUN
admet-162	120	19	,	,	PUNCT
admet-162	120	20	hypoxia	hypoxia	NOUN
admet-162	120	21	,	,	PUNCT
admet-162	120	22	inflammation	inflammation	NOUN
admet-162	120	23	,	,	PUNCT
admet-162	120	24	drugs	drug	NOUN
admet-162	120	25	,	,	PUNCT
admet-162	120	26	cytokines	cytokine	NOUN
admet-162	120	27	,	,	PUNCT
admet-162	120	28	tumors	tumor	NOUN
admet-162	120	29	,	,	PUNCT
admet-162	120	30	metabolic	metabolic	NOUN
admet-162	120	31	disorders	disorder	NOUN
admet-162	120	32	,	,	PUNCT
admet-162	120	33	toxics	toxic	NOUN
admet-162	120	34	,	,	PUNCT
admet-162	120	35	trauma	trauma	NOUN
admet-162	120	36	,	,	PUNCT
admet-162	120	37	or	or	CCONJ
admet-162	120	38	infections	infection	NOUN
admet-162	120	39	.	.	PUNCT
admet-162	121	1	irrespective	irrespective	ADJ
admet-162	121	2	which	which	PRON
admet-162	121	3	was	be	AUX
admet-162	121	4	the	the	DET
admet-162	121	5	cause	cause	NOUN
admet-162	121	6	,	,	PUNCT
admet-162	121	7	in	in	ADP
admet-162	121	8	these	these	DET
admet-162	121	9	conditions	condition	NOUN
admet-162	121	10	neuronal	neuronal	ADJ
admet-162	121	11	membranes	membrane	NOUN
admet-162	121	12	will	will	AUX
admet-162	121	13	be	be	AUX
admet-162	121	14	depolarized	depolarize	VERB
admet-162	121	15	.	.	PUNCT
admet-162	122	1	interestingly	interestingly	ADV
admet-162	122	2	,	,	PUNCT
admet-162	122	3	all	all	DET
admet-162	122	4	these	these	DET
admet-162	122	5	mentioned	mention	VERB
admet-162	122	6	factors	factor	NOUN
admet-162	122	7	are	be	AUX
admet-162	122	8	the	the	DET
admet-162	122	9	more	more	ADV
admet-162	122	10	common	common	ADJ
admet-162	122	11	conditions	condition	NOUN
admet-162	122	12	that	that	PRON
admet-162	122	13	develop	develop	VERB
admet-162	122	14	acquired	acquire	VERB
admet-162	122	15	epilepsy	epilepsy	NOUN
admet-162	122	16	.	.	PUNCT
admet-162	123	1	admet	admet	PROPN
admet-162	123	2	&	&	CCONJ
admet-162	123	3	dmpk	dmpk	PROPN
admet-162	123	4	3(2	3(2	NUM
admet-162	123	5	)	)	PUNCT
admet-162	123	6	(	(	PUNCT
admet-162	123	7	2015	2015	NUM
admet-162	123	8	)	)	PUNCT
admet-162	123	9	110	110	NUM
admet-162	123	10	-	-	SYM
admet-162	123	11	121	121	NUM
admet-162	123	12	the	the	DET
admet-162	123	13	roles	role	NOUN
admet-162	123	14	of	of	ADP
admet-162	123	15	p	p	NOUN
admet-162	123	16	-	-	PUNCT
admet-162	123	17	gp	gp	NOUN
admet-162	123	18	in	in	ADP
admet-162	123	19	refractory	refractory	NOUN
admet-162	123	20	epilepsy	epilepsy	NOUN
admet-162	123	21	doi	doi	NOUN
admet-162	123	22	:	:	PUNCT
admet-162	123	23	10.5599	10.5599	NUM
admet-162	123	24	/	/	SYM
admet-162	123	25	admet.3.2.162	admet.3.2.162	ADP
admet-162	123	26	117	117	NUM
admet-162	123	27	the	the	DET
admet-162	123	28	time	time	NOUN
admet-162	123	29	course	course	NOUN
admet-162	123	30	for	for	ADP
admet-162	123	31	the	the	DET
admet-162	123	32	expression	expression	NOUN
admet-162	123	33	of	of	ADP
admet-162	123	34	p	p	NOUN
admet-162	123	35	-	-	PUNCT
admet-162	123	36	gp	gp	NOUN
admet-162	123	37	in	in	ADP
admet-162	123	38	astrocytes	astrocyte	NOUN
admet-162	123	39	after	after	SCONJ
admet-162	123	40	status	status	NOUN
admet-162	123	41	epilepticus	epilepticus	VERB
admet-162	123	42	following	follow	VERB
admet-162	123	43	intracerebroventricular	intracerebroventricular	ADJ
admet-162	123	44	kainate	kainate	NOUN
admet-162	123	45	injection	injection	NOUN
admet-162	123	46	,	,	PUNCT
admet-162	123	47	was	be	AUX
admet-162	123	48	10	10	NUM
admet-162	123	49	consecutive	consecutive	ADJ
admet-162	123	50	weeks	week	NOUN
admet-162	124	1	[	[	X
admet-162	124	2	25	25	NUM
admet-162	124	3	]	]	PUNCT
admet-162	124	4	,	,	PUNCT
admet-162	124	5	and	and	CCONJ
admet-162	124	6	after	after	ADP
admet-162	124	7	the	the	DET
admet-162	124	8	cortical	cortical	ADJ
admet-162	124	9	devascularization	devascularization	NOUN
admet-162	124	10	inducing	induce	VERB
admet-162	124	11	focal	focal	ADJ
admet-162	124	12	hypoxia	hypoxia	NOUN
admet-162	124	13	,	,	PUNCT
admet-162	124	14	p	p	NOUN
admet-162	124	15	-	-	PUNCT
admet-162	124	16	gp	gp	NOUN
admet-162	124	17	expression	expression	NOUN
admet-162	124	18	in	in	ADP
admet-162	124	19	neurons	neuron	NOUN
admet-162	124	20	was	be	AUX
admet-162	124	21	maximal	maximal	ADJ
admet-162	124	22	at	at	ADP
admet-162	124	23	day	day	NOUN
admet-162	124	24	7	7	NUM
admet-162	124	25	,	,	PUNCT
admet-162	124	26	and	and	CCONJ
admet-162	124	27	remained	remain	VERB
admet-162	124	28	lightly	lightly	ADV
admet-162	124	29	positive	positive	ADJ
admet-162	124	30	at	at	ADP
admet-162	124	31	day	day	NOUN
admet-162	124	32	28	28	NUM
admet-162	125	1	[	[	X
admet-162	125	2	58	58	NUM
admet-162	125	3	]	]	PUNCT
admet-162	125	4	.	.	PUNCT
admet-162	126	1	p	p	X
admet-162	126	2	-	-	PUNCT
admet-162	126	3	gp	gp	NOUN
admet-162	126	4	could	could	AUX
admet-162	126	5	be	be	AUX
admet-162	126	6	expressed	express	VERB
admet-162	126	7	longer	long	ADJ
admet-162	126	8	times	time	NOUN
admet-162	126	9	depending	depend	VERB
admet-162	126	10	on	on	ADP
admet-162	126	11	the	the	DET
admet-162	126	12	severity	severity	NOUN
admet-162	126	13	and	and	CCONJ
admet-162	126	14	also	also	ADV
admet-162	126	15	the	the	DET
admet-162	126	16	frequency	frequency	NOUN
admet-162	126	17	of	of	ADP
admet-162	126	18	the	the	DET
admet-162	126	19	repetitive	repetitive	ADJ
admet-162	126	20	inducer	inducer	NOUN
admet-162	126	21	stimulus	stimulus	NOUN
admet-162	126	22	.	.	PUNCT
admet-162	127	1	so	so	ADV
admet-162	127	2	,	,	PUNCT
admet-162	127	3	we	we	PRON
admet-162	127	4	can	can	AUX
admet-162	127	5	speculate	speculate	VERB
admet-162	127	6	that	that	SCONJ
admet-162	127	7	time	time	NOUN
admet-162	127	8	during	during	ADP
admet-162	127	9	neuronal	neuronal	ADJ
admet-162	127	10	p	p	NOUN
admet-162	127	11	-	-	PUNCT
admet-162	127	12	gp	gp	NOUN
admet-162	127	13	remains	remain	NOUN
admet-162	127	14	expressed	express	VERB
admet-162	127	15	,	,	PUNCT
admet-162	127	16	results	result	VERB
admet-162	127	17	in	in	ADP
admet-162	127	18	a	a	DET
admet-162	127	19	pharmacoresistant	pharmacoresistant	ADJ
admet-162	127	20	window	window	NOUN
admet-162	127	21	,	,	PUNCT
admet-162	127	22	or	or	CCONJ
admet-162	127	23	the	the	DET
admet-162	127	24	time	time	NOUN
admet-162	127	25	during	during	ADP
admet-162	127	26	the	the	DET
admet-162	127	27	patients	patient	NOUN
admet-162	127	28	have	have	VERB
admet-162	127	29	higher	high	ADJ
admet-162	127	30	risk	risk	NOUN
admet-162	127	31	to	to	PART
admet-162	127	32	get	get	VERB
admet-162	127	33	a	a	DET
admet-162	127	34	new	new	ADJ
admet-162	127	35	seizures	seizure	NOUN
admet-162	127	36	,	,	PUNCT
admet-162	127	37	or	or	CCONJ
admet-162	127	38	both	both	DET
admet-162	127	39	conditions	condition	NOUN
admet-162	127	40	.	.	PUNCT
admet-162	128	1	if	if	SCONJ
admet-162	128	2	it	it	PRON
admet-162	128	3	is	be	AUX
admet-162	128	4	the	the	DET
admet-162	128	5	case	case	NOUN
admet-162	128	6	,	,	PUNCT
admet-162	128	7	pharmacoresistance	pharmacoresistance	NOUN
admet-162	128	8	and	and	CCONJ
admet-162	128	9	epileptogenesis	epileptogenesis	NOUN
admet-162	128	10	are	be	AUX
admet-162	128	11	sharing	share	VERB
admet-162	128	12	the	the	DET
admet-162	128	13	same	same	ADJ
admet-162	128	14	mechanistic	mechanistic	ADJ
admet-162	128	15	risk	risk	NOUN
admet-162	128	16	factor	factor	NOUN
admet-162	128	17	:	:	PUNCT
admet-162	128	18	“	"	PUNCT
admet-162	128	19	p	p	X
admet-162	128	20	-	-	PUNCT
admet-162	128	21	gp	gp	NOUN
admet-162	128	22	expressed	express	VERB
admet-162	128	23	in	in	ADP
admet-162	128	24	neurons	neuron	NOUN
admet-162	128	25	”	"	PUNCT
admet-162	128	26	.	.	PUNCT
admet-162	129	1	p	p	X
admet-162	129	2	-	-	PUNCT
admet-162	129	3	glycoprotein	glycoprotein	NOUN
admet-162	129	4	and	and	CCONJ
admet-162	129	5	sudden	sudden	ADJ
admet-162	129	6	unexpected	unexpected	ADJ
admet-162	129	7	death	death	NOUN
admet-162	129	8	in	in	ADP
admet-162	129	9	epilepsy	epilepsy	PROPN
admet-162	129	10	(	(	PUNCT
admet-162	129	11	sudep	sudep	NOUN
admet-162	129	12	)	)	PUNCT
admet-162	129	13	patients	patient	NOUN
admet-162	129	14	with	with	ADP
admet-162	129	15	refractory	refractory	NOUN
admet-162	129	16	epilepsy	epilepsy	NOUN
admet-162	129	17	carry	carry	VERB
admet-162	129	18	an	an	DET
admet-162	129	19	increased	increase	VERB
admet-162	129	20	mortality	mortality	NOUN
admet-162	129	21	risk	risk	NOUN
admet-162	129	22	of	of	ADP
admet-162	129	23	that	that	PRON
admet-162	129	24	is	be	AUX
admet-162	129	25	more	more	ADV
admet-162	129	26	elevated	elevated	ADJ
admet-162	129	27	than	than	ADP
admet-162	129	28	in	in	ADP
admet-162	129	29	patients	patient	NOUN
admet-162	129	30	with	with	ADP
admet-162	129	31	well	well	ADV
admet-162	129	32	-	-	PUNCT
admet-162	129	33	controlled	control	VERB
admet-162	129	34	seizures	seizure	NOUN
admet-162	129	35	.	.	PUNCT
admet-162	130	1	the	the	PRON
admet-162	130	2	sudden	sudden	ADJ
admet-162	130	3	,	,	PUNCT
admet-162	130	4	unexpected	unexpected	ADJ
admet-162	130	5	,	,	PUNCT
admet-162	130	6	witnessed	witness	VERB
admet-162	130	7	or	or	CCONJ
admet-162	130	8	unwitnessed	unwitnesse	VERB
admet-162	130	9	,	,	PUNCT
admet-162	130	10	no	no	DET
admet-162	130	11	traumatic	traumatic	ADJ
admet-162	130	12	and	and	CCONJ
admet-162	130	13	no	no	DET
admet-162	130	14	drowning	drown	VERB
admet-162	130	15	deaths	death	NOUN
admet-162	130	16	in	in	ADP
admet-162	130	17	patients	patient	NOUN
admet-162	130	18	with	with	ADP
admet-162	130	19	epilepsy	epilepsy	NOUN
admet-162	130	20	,	,	PUNCT
admet-162	130	21	is	be	AUX
admet-162	130	22	usually	usually	ADV
admet-162	130	23	a	a	DET
admet-162	130	24	clinical	clinical	ADJ
admet-162	130	25	phenomenon	phenomenon	NOUN
admet-162	130	26	in	in	ADP
admet-162	130	27	which	which	PRON
admet-162	130	28	post	post	ADJ
admet-162	130	29	-	-	ADJ
admet-162	130	30	mortem	mortem	ADJ
admet-162	130	31	examination	examination	NOUN
admet-162	130	32	does	do	AUX
admet-162	130	33	not	not	PART
admet-162	130	34	reveal	reveal	VERB
admet-162	130	35	a	a	DET
admet-162	130	36	toxicological	toxicological	ADJ
admet-162	130	37	or	or	CCONJ
admet-162	130	38	anatomical	anatomical	ADJ
admet-162	130	39	cause	cause	NOUN
admet-162	130	40	of	of	ADP
admet-162	130	41	death	death	NOUN
admet-162	130	42	[	[	X
admet-162	130	43	59	59	NUM
admet-162	130	44	]	]	PUNCT
admet-162	130	45	.	.	PUNCT
admet-162	131	1	the	the	DET
admet-162	131	2	clinical	clinical	ADJ
admet-162	131	3	characteristics	characteristic	NOUN
admet-162	131	4	of	of	ADP
admet-162	131	5	patients	patient	NOUN
admet-162	131	6	with	with	ADP
admet-162	131	7	epilepsy	epilepsy	NOUN
admet-162	131	8	at	at	ADP
admet-162	131	9	particular	particular	ADJ
admet-162	131	10	risk	risk	NOUN
admet-162	131	11	for	for	ADP
admet-162	131	12	sudep	sudep	NOUN
admet-162	131	13	are	be	AUX
admet-162	131	14	related	relate	VERB
admet-162	131	15	with	with	ADP
admet-162	131	16	a	a	DET
admet-162	131	17	long	long	ADJ
admet-162	131	18	history	history	NOUN
admet-162	131	19	(	(	PUNCT
admet-162	131	20	more	more	ADJ
admet-162	131	21	than	than	ADP
admet-162	131	22	15	15	NUM
admet-162	131	23	years	year	NOUN
admet-162	131	24	)	)	PUNCT
admet-162	131	25	of	of	ADP
admet-162	131	26	pharmacoresistant	pharmacoresistant	ADJ
admet-162	131	27	epilepsy	epilepsy	NOUN
admet-162	131	28	or	or	CCONJ
admet-162	131	29	high	high	ADJ
admet-162	131	30	seizure	seizure	NOUN
admet-162	131	31	frequency	frequency	NOUN
admet-162	131	32	(	(	PUNCT
admet-162	131	33	more	more	ADJ
admet-162	131	34	than	than	ADP
admet-162	131	35	15	15	NUM
admet-162	131	36	seizures	seizure	NOUN
admet-162	131	37	/	/	SYM
admet-162	131	38	moth	moth	NOUN
admet-162	131	39	)	)	PUNCT
admet-162	131	40	.	.	PUNCT
admet-162	132	1	all	all	DET
admet-162	132	2	these	these	DET
admet-162	132	3	patients	patient	NOUN
admet-162	132	4	currently	currently	ADV
admet-162	132	5	receive	receive	VERB
admet-162	132	6	antiepileptic	antiepileptic	ADJ
admet-162	132	7	drug	drug	NOUN
admet-162	132	8	(	(	PUNCT
admet-162	132	9	aed	aed	NOUN
admet-162	132	10	)	)	PUNCT
admet-162	132	11	polypharmacy	polypharmacy	NOUN
admet-162	132	12	,	,	PUNCT
admet-162	132	13	and	and	CCONJ
admet-162	132	14	commonly	commonly	ADV
admet-162	132	15	changes	change	NOUN
admet-162	132	16	between	between	ADP
admet-162	132	17	different	different	ADJ
admet-162	132	18	therapeutic	therapeutic	ADJ
admet-162	132	19	combinations	combination	NOUN
admet-162	132	20	and/or	and/or	CCONJ
admet-162	132	21	doses	dose	NOUN
admet-162	132	22	.	.	PUNCT
admet-162	133	1	persistent	persistent	ADJ
admet-162	133	2	low	low	ADJ
admet-162	133	3	levels	level	NOUN
admet-162	133	4	of	of	ADP
admet-162	133	5	aeds	aed	NOUN
admet-162	133	6	in	in	ADP
admet-162	133	7	plasma	plasma	NOUN
admet-162	133	8	as	as	ADV
admet-162	133	9	well	well	ADV
admet-162	133	10	as	as	ADP
admet-162	133	11	poor	poor	ADJ
admet-162	133	12	adherence	adherence	NOUN
admet-162	133	13	to	to	ADP
admet-162	133	14	pharmacotherapy	pharmacotherapy	NOUN
admet-162	133	15	are	be	AUX
admet-162	133	16	also	also	ADV
admet-162	133	17	observed	observe	VERB
admet-162	133	18	in	in	ADP
admet-162	133	19	these	these	DET
admet-162	133	20	patients	patient	NOUN
admet-162	133	21	,	,	PUNCT
admet-162	133	22	and	and	CCONJ
admet-162	133	23	several	several	ADJ
admet-162	133	24	of	of	ADP
admet-162	133	25	all	all	PRON
admet-162	133	26	of	of	ADP
admet-162	133	27	these	these	DET
admet-162	133	28	features	feature	NOUN
admet-162	133	29	are	be	AUX
admet-162	133	30	associated	associate	VERB
admet-162	133	31	to	to	PART
admet-162	133	32	pharmacoresistant	pharmacoresistant	VERB
admet-162	133	33	epilepsy	epilepsy	NOUN
admet-162	133	34	[	[	X
admet-162	133	35	60	60	NUM
admet-162	133	36	]	]	PUNCT
admet-162	133	37	.	.	PUNCT
admet-162	134	1	different	different	ADJ
admet-162	134	2	studies	study	NOUN
admet-162	134	3	have	have	AUX
admet-162	134	4	suggested	suggest	VERB
admet-162	134	5	that	that	SCONJ
admet-162	134	6	seizure	seizure	NOUN
admet-162	134	7	activity	activity	NOUN
admet-162	134	8	as	as	ADP
admet-162	134	9	inducer	inducer	NOUN
admet-162	134	10	of	of	ADP
admet-162	134	11	cardiovascular	cardiovascular	ADJ
admet-162	134	12	alterations	alteration	NOUN
admet-162	134	13	,	,	PUNCT
admet-162	134	14	changes	change	NOUN
admet-162	134	15	in	in	ADP
admet-162	134	16	the	the	DET
admet-162	134	17	respiratory	respiratory	ADJ
admet-162	134	18	rate	rate	NOUN
admet-162	134	19	including	include	VERB
admet-162	134	20	tachypnea	tachypnea	NOUN
admet-162	134	21	,	,	PUNCT
admet-162	134	22	hypopnea	hypopnea	NOUN
admet-162	134	23	or	or	CCONJ
admet-162	134	24	apnea	apnea	VERB
admet-162	134	25	,	,	PUNCT
admet-162	134	26	related	relate	VERB
admet-162	134	27	also	also	ADV
admet-162	134	28	with	with	ADP
admet-162	134	29	heart	heart	NOUN
admet-162	134	30	ischemia	ischemia	NOUN
admet-162	134	31	,	,	PUNCT
admet-162	134	32	suggesting	suggest	VERB
admet-162	134	33	that	that	SCONJ
admet-162	134	34	respiratory	respiratory	ADJ
admet-162	134	35	and	and	CCONJ
admet-162	134	36	mainly	mainly	ADV
admet-162	134	37	cardiovascular	cardiovascular	ADJ
admet-162	134	38	abnormalities	abnormality	NOUN
admet-162	134	39	during	during	ADP
admet-162	134	40	and	and	CCONJ
admet-162	134	41	between	between	ADP
admet-162	134	42	seizures	seizure	NOUN
admet-162	134	43	,	,	PUNCT
admet-162	134	44	could	could	AUX
admet-162	134	45	play	play	VERB
admet-162	134	46	a	a	DET
admet-162	134	47	central	central	ADJ
admet-162	134	48	role	role	NOUN
admet-162	134	49	in	in	ADP
admet-162	134	50	sudep	sudep	NOUN
admet-162	134	51	[	[	X
admet-162	134	52	61	61	NUM
admet-162	134	53	-	-	SYM
admet-162	134	54	63	63	NUM
admet-162	134	55	]	]	PUNCT
admet-162	134	56	.	.	PUNCT
admet-162	135	1	it	it	PRON
admet-162	135	2	was	be	AUX
admet-162	135	3	also	also	ADV
admet-162	135	4	experimentally	experimentally	ADV
admet-162	135	5	demonstrated	demonstrate	VERB
admet-162	135	6	that	that	SCONJ
admet-162	135	7	after	after	ADP
admet-162	135	8	both	both	CCONJ
admet-162	135	9	acute	acute	ADJ
admet-162	135	10	or	or	CCONJ
admet-162	135	11	chronic	chronic	ADJ
admet-162	135	12	heart	heart	NOUN
admet-162	135	13	hypoxia	hypoxia	NOUN
admet-162	135	14	,	,	PUNCT
admet-162	135	15	p	p	NOUN
admet-162	135	16	-	-	PUNCT
admet-162	135	17	glycoprotein	glycoprotein	NOUN
admet-162	135	18	results	result	NOUN
admet-162	135	19	to	to	PART
admet-162	135	20	be	be	AUX
admet-162	135	21	overexpressed	overexpresse	VERB
admet-162	135	22	in	in	ADP
admet-162	135	23	cardiomyocytes	cardiomyocyte	NOUN
admet-162	135	24	and	and	CCONJ
admet-162	135	25	associated	associate	VERB
admet-162	135	26	with	with	ADP
admet-162	135	27	heart	heart	NOUN
admet-162	135	28	stunning	stunning	ADJ
admet-162	135	29	[	[	X
admet-162	135	30	64,65	64,65	NOUN
admet-162	135	31	]	]	PUNCT
admet-162	135	32	.	.	PUNCT
admet-162	136	1	according	accord	VERB
admet-162	136	2	with	with	ADP
admet-162	136	3	these	these	DET
admet-162	136	4	observations	observation	NOUN
admet-162	136	5	it	it	PRON
admet-162	136	6	is	be	AUX
admet-162	136	7	important	important	ADJ
admet-162	136	8	notice	notice	NOUN
admet-162	136	9	that	that	SCONJ
admet-162	136	10	continuous	continuous	ADJ
admet-162	136	11	convulsive	convulsive	ADJ
admet-162	136	12	stress	stress	NOUN
admet-162	136	13	could	could	AUX
admet-162	136	14	mimic	mimic	VERB
admet-162	136	15	a	a	DET
admet-162	136	16	repetitive	repetitive	ADJ
admet-162	136	17	apneas	apnea	NOUN
admet-162	136	18	or	or	CCONJ
admet-162	136	19	hypoxia	hypoxia	NOUN
admet-162	136	20	and	and	CCONJ
admet-162	136	21	produce	produce	VERB
admet-162	136	22	heart	heart	NOUN
admet-162	136	23	ischemia	ischemia	NOUN
admet-162	136	24	.	.	PUNCT
admet-162	137	1	in	in	ADP
admet-162	137	2	bases	basis	NOUN
admet-162	137	3	to	to	ADP
admet-162	137	4	these	these	DET
admet-162	137	5	considerations	consideration	NOUN
admet-162	137	6	,	,	PUNCT
admet-162	137	7	the	the	DET
admet-162	137	8	progressive	progressive	ADJ
admet-162	137	9	and	and	CCONJ
admet-162	137	10	simultaneous	simultaneous	ADJ
admet-162	137	11	p	p	NOUN
admet-162	137	12	-	-	PUNCT
admet-162	137	13	gp	gp	NOUN
admet-162	137	14	overexpression	overexpression	NOUN
admet-162	137	15	in	in	ADP
admet-162	137	16	brain	brain	NOUN
admet-162	137	17	and	and	CCONJ
admet-162	137	18	heart	heart	NOUN
admet-162	137	19	,	,	PUNCT
admet-162	137	20	related	relate	VERB
admet-162	137	21	with	with	ADP
admet-162	137	22	the	the	DET
admet-162	137	23	development	development	NOUN
admet-162	137	24	of	of	ADP
admet-162	137	25	fatal	fatal	ADJ
admet-162	137	26	status	status	NOUN
admet-162	137	27	epilepticus	epilepticus	VERB
admet-162	137	28	after	after	SCONJ
admet-162	137	29	experimental	experimental	ADJ
admet-162	137	30	repetitive	repetitive	ADJ
admet-162	137	31	seizures	seizure	NOUN
admet-162	137	32	was	be	AUX
admet-162	137	33	recently	recently	ADV
admet-162	137	34	demonstrated	demonstrate	VERB
admet-162	137	35	by	by	ADP
admet-162	137	36	our	our	PRON
admet-162	137	37	group	group	NOUN
admet-162	138	1	[	[	X
admet-162	138	2	66	66	NUM
admet-162	138	3	]	]	PUNCT
admet-162	138	4	.	.	PUNCT
admet-162	139	1	furthermore	furthermore	ADV
admet-162	139	2	,	,	PUNCT
admet-162	139	3	we	we	PRON
admet-162	139	4	can	can	AUX
admet-162	139	5	speculate	speculate	VERB
admet-162	139	6	that	that	SCONJ
admet-162	139	7	high	high	ADJ
admet-162	139	8	p	p	NOUN
admet-162	139	9	-	-	PUNCT
admet-162	139	10	gp	gp	NOUN
admet-162	139	11	expression	expression	NOUN
admet-162	139	12	in	in	ADP
admet-162	139	13	brain	brain	NOUN
admet-162	139	14	,	,	PUNCT
admet-162	139	15	particularly	particularly	ADV
admet-162	139	16	in	in	ADP
admet-162	139	17	neurons	neuron	NOUN
admet-162	139	18	(	(	PUNCT
admet-162	139	19	as	as	SCONJ
admet-162	139	20	previously	previously	ADV
admet-162	139	21	described	describe	VERB
admet-162	139	22	above	above	ADP
admet-162	139	23	)	)	PUNCT
admet-162	139	24	,	,	PUNCT
admet-162	139	25	could	could	AUX
admet-162	139	26	play	play	VERB
admet-162	139	27	a	a	DET
admet-162	139	28	role	role	NOUN
admet-162	139	29	on	on	ADP
admet-162	139	30	the	the	DET
admet-162	139	31	risk	risk	NOUN
admet-162	139	32	for	for	ADP
admet-162	139	33	se	se	PROPN
admet-162	139	34	development	development	NOUN
admet-162	139	35	,	,	PUNCT
admet-162	139	36	and	and	CCONJ
admet-162	139	37	high	high	ADJ
admet-162	139	38	p	p	NOUN
admet-162	139	39	-	-	PUNCT
admet-162	139	40	gp	gp	NOUN
admet-162	139	41	expression	expression	NOUN
admet-162	139	42	in	in	ADP
admet-162	139	43	heart	heart	NOUN
admet-162	139	44	could	could	AUX
admet-162	139	45	play	play	VERB
admet-162	139	46	a	a	DET
admet-162	139	47	role	role	NOUN
admet-162	139	48	in	in	ADP
admet-162	139	49	the	the	DET
admet-162	139	50	risk	risk	NOUN
admet-162	139	51	for	for	ADP
admet-162	139	52	develop	develop	VERB
admet-162	139	53	an	an	DET
admet-162	139	54	acute	acute	ADJ
admet-162	139	55	and	and	CCONJ
admet-162	139	56	fatal	fatal	ADJ
admet-162	139	57	heart	heart	NOUN
admet-162	139	58	failure	failure	NOUN
admet-162	139	59	.	.	PUNCT
admet-162	140	1	p	p	X
admet-162	140	2	-	-	PUNCT
admet-162	140	3	gp	gp	NOUN
admet-162	140	4	as	as	ADP
admet-162	140	5	stem	stem	NOUN
admet-162	140	6	cell	cell	NOUN
admet-162	140	7	marker	marker	NOUN
admet-162	140	8	of	of	ADP
admet-162	140	9	brain	brain	NOUN
admet-162	140	10	malformation	malformation	NOUN
admet-162	140	11	/	/	SYM
admet-162	140	12	tumor	tumor	NOUN
admet-162	140	13	refractory	refractory	NOUN
admet-162	140	14	epilepsies	epilepsy	NOUN
admet-162	140	15	and/or	and/or	CCONJ
admet-162	140	16	relapsing	relapse	VERB
admet-162	140	17	marker	marker	NOUN
admet-162	140	18	after	after	SCONJ
admet-162	140	19	surgical	surgical	ADJ
admet-162	140	20	treatment	treatment	NOUN
admet-162	140	21	several	several	ADJ
admet-162	140	22	malformations	malformation	NOUN
admet-162	140	23	of	of	ADP
admet-162	140	24	cortical	cortical	ADJ
admet-162	140	25	development	development	NOUN
admet-162	140	26	as	as	ADV
admet-162	140	27	well	well	ADV
admet-162	140	28	as	as	ADP
admet-162	140	29	brain	brain	NOUN
admet-162	140	30	tumors	tumor	NOUN
admet-162	140	31	are	be	AUX
admet-162	140	32	associated	associate	VERB
admet-162	140	33	with	with	ADP
admet-162	140	34	refractory	refractory	NOUN
admet-162	140	35	epileptic	epileptic	ADJ
admet-162	140	36	syndromes	syndrome	NOUN
admet-162	140	37	and/or	and/or	CCONJ
admet-162	140	38	developmental	developmental	ADJ
admet-162	140	39	delay	delay	NOUN
admet-162	140	40	.	.	PUNCT
admet-162	141	1	the	the	DET
admet-162	141	2	main	main	ADJ
admet-162	141	3	developmental	developmental	ADJ
admet-162	141	4	brain	brain	NOUN
admet-162	141	5	abnormalities	abnormality	NOUN
admet-162	141	6	identified	identify	VERB
admet-162	141	7	are	be	AUX
admet-162	141	8	hemimegalencephaly	hemimegalencephaly	NOUN
admet-162	141	9	,	,	PUNCT
admet-162	141	10	polymicrogyria	polymicrogyria	NOUN
admet-162	141	11	,	,	PUNCT
admet-162	141	12	agyria	agyria	PROPN
admet-162	141	13	-	-	PUNCT
admet-162	141	14	pachygyria	pachygyria	PROPN
admet-162	141	15	,	,	PUNCT
admet-162	141	16	schizencephaly	schizencephaly	NOUN
admet-162	141	17	,	,	PUNCT
admet-162	141	18	heterotopic	heterotopic	ADJ
admet-162	141	19	gray	gray	ADJ
admet-162	141	20	matter	matter	NOUN
admet-162	141	21	,	,	PUNCT
admet-162	141	22	transmantle	transmantle	NOUN
admet-162	141	23	dysplasia	dysplasia	ADJ
admet-162	141	24	,	,	PUNCT
admet-162	141	25	focal	focal	ADJ
admet-162	141	26	cortical	cortical	ADJ
admet-162	141	27	dysplasia	dysplasia	NOUN
admet-162	141	28	,	,	PUNCT
admet-162	141	29	or	or	CCONJ
admet-162	141	30	cortical	cortical	ADJ
admet-162	141	31	tubers	tuber	NOUN
admet-162	141	32	.	.	PUNCT
admet-162	142	1	p	p	X
admet-162	142	2	-	-	PUNCT
admet-162	142	3	gp	gp	NOUN
admet-162	142	4	and	and	CCONJ
admet-162	142	5	others	other	NOUN
admet-162	142	6	abc	abc	PROPN
admet-162	142	7	-	-	PUNCT
admet-162	142	8	transporters	transporter	NOUN
admet-162	142	9	have	have	AUX
admet-162	142	10	been	be	AUX
admet-162	142	11	reported	report	VERB
admet-162	142	12	to	to	PART
admet-162	142	13	be	be	AUX
admet-162	142	14	over	over	ADV
admet-162	142	15	-	-	PUNCT
admet-162	142	16	expressed	express	VERB
admet-162	142	17	in	in	ADP
admet-162	142	18	these	these	DET
admet-162	142	19	malformations	malformation	NOUN
admet-162	142	20	of	of	ADP
admet-162	142	21	cortical	cortical	ADJ
admet-162	142	22	development	development	NOUN
admet-162	142	23	and	and	CCONJ
admet-162	142	24	brain	brain	NOUN
admet-162	142	25	cortical	cortical	ADJ
admet-162	142	26	tubers	tuber	NOUN
admet-162	142	27	explaining	explain	VERB
admet-162	142	28	why	why	SCONJ
admet-162	142	29	all	all	PRON
admet-162	142	30	of	of	ADP
admet-162	142	31	them	they	PRON
admet-162	142	32	are	be	AUX
admet-162	142	33	clinically	clinically	ADV
admet-162	142	34	characterized	characterize	VERB
admet-162	142	35	by	by	ADP
admet-162	142	36	phamacoresistant	phamacoresistant	ADJ
admet-162	142	37	phenotype	phenotype	NOUN
admet-162	142	38	[	[	X
admet-162	142	39	22,23,67,68	22,23,67,68	NUM
admet-162	142	40	]	]	PUNCT
admet-162	142	41	.	.	PUNCT
admet-162	143	1	epilepsy	epilepsy	PROPN
admet-162	143	2	is	be	AUX
admet-162	143	3	also	also	ADV
admet-162	143	4	common	common	ADJ
admet-162	143	5	disorder	disorder	NOUN
admet-162	143	6	in	in	ADP
admet-162	143	7	patients	patient	NOUN
admet-162	143	8	with	with	ADP
admet-162	143	9	brain	brain	NOUN
admet-162	143	10	tumors	tumor	NOUN
admet-162	143	11	and	and	CCONJ
admet-162	143	12	can	can	AUX
admet-162	143	13	substantially	substantially	ADV
admet-162	143	14	affect	affect	VERB
admet-162	143	15	lazarowski	lazarowski	PROPN
admet-162	143	16	et	et	PROPN
admet-162	143	17	al	al	PROPN
admet-162	143	18	.	.	PROPN
admet-162	143	19	admet	admet	PROPN
admet-162	143	20	&	&	CCONJ
admet-162	143	21	dmpk	dmpk	PROPN
admet-162	143	22	3(2	3(2	NUM
admet-162	143	23	)	)	PUNCT
admet-162	143	24	(	(	PUNCT
admet-162	143	25	2015	2015	NUM
admet-162	143	26	)	)	PUNCT
admet-162	143	27	110	110	NUM
admet-162	143	28	-	-	SYM
admet-162	143	29	121	121	NUM
admet-162	143	30	118	118	NUM
admet-162	143	31	daily	daily	ADJ
admet-162	143	32	life	life	NOUN
admet-162	143	33	,	,	PUNCT
admet-162	143	34	even	even	ADV
admet-162	143	35	if	if	SCONJ
admet-162	143	36	the	the	DET
admet-162	143	37	tumor	tumor	NOUN
admet-162	143	38	is	be	AUX
admet-162	143	39	under	under	ADP
admet-162	143	40	control	control	NOUN
admet-162	143	41	.	.	PUNCT
admet-162	144	1	in	in	ADP
admet-162	144	2	these	these	DET
admet-162	144	3	cases	case	NOUN
admet-162	144	4	,	,	PUNCT
admet-162	144	5	multidrug	multidrug	NOUN
admet-162	144	6	-	-	PUNCT
admet-162	144	7	abc	abc	NOUN
admet-162	144	8	-	-	PUNCT
admet-162	144	9	transporters	transporter	NOUN
admet-162	144	10	expressed	express	VERB
admet-162	144	11	at	at	ADP
admet-162	144	12	blood	blood	NOUN
admet-162	144	13	brain	brain	NOUN
admet-162	144	14	barrier	barrier	NOUN
admet-162	144	15	,	,	PUNCT
admet-162	144	16	brain	brain	NOUN
admet-162	144	17	tumor	tumor	NOUN
admet-162	144	18	cells	cell	NOUN
admet-162	144	19	and	and	CCONJ
admet-162	144	20	tumor	tumor	NOUN
admet-162	144	21	-	-	PUNCT
admet-162	144	22	surrounding	surround	VERB
admet-162	144	23	cells	cell	NOUN
admet-162	144	24	,	,	PUNCT
admet-162	144	25	prevent	prevent	VERB
admet-162	144	26	the	the	DET
admet-162	144	27	access	access	NOUN
admet-162	144	28	of	of	ADP
admet-162	144	29	antiepileptic	antiepileptic	ADJ
admet-162	144	30	drugs	drug	NOUN
admet-162	144	31	into	into	ADP
admet-162	144	32	brain	brain	NOUN
admet-162	144	33	parenchyma	parenchyma	NOUN
admet-162	144	34	,	,	PUNCT
admet-162	144	35	and	and	CCONJ
admet-162	144	36	patients	patient	NOUN
admet-162	144	37	develop	develop	VERB
admet-162	144	38	a	a	DET
admet-162	144	39	refractory	refractory	NOUN
admet-162	144	40	phenotype	phenotype	NOUN
admet-162	144	41	.	.	PUNCT
admet-162	145	1	in	in	ADP
admet-162	145	2	subependimmal	subependimmal	ADJ
admet-162	145	3	giant	giant	ADJ
admet-162	145	4	astrocytoma	astrocytoma	PROPN
admet-162	145	5	(	(	PUNCT
admet-162	145	6	sega	sega	NOUN
admet-162	145	7	)	)	PUNCT
admet-162	145	8	,	,	PUNCT
admet-162	145	9	abc	abc	PROPN
admet-162	145	10	-	-	PUNCT
admet-162	145	11	transporters	transporter	NOUN
admet-162	145	12	(	(	PUNCT
admet-162	145	13	p	p	NOUN
admet-162	145	14	-	-	PUNCT
admet-162	145	15	gp	gp	NOUN
admet-162	145	16	and	and	CCONJ
admet-162	145	17	bcrp	bcrp	ADV
admet-162	145	18	)	)	PUNCT
admet-162	145	19	and	and	CCONJ
admet-162	145	20	cd34	cd34	PROPN
admet-162	145	21	stem	stem	NOUN
admet-162	145	22	cell	cell	NOUN
admet-162	145	23	markers	marker	NOUN
admet-162	145	24	were	be	AUX
admet-162	145	25	highly	highly	ADV
admet-162	145	26	expressed	express	VERB
admet-162	145	27	in	in	ADP
admet-162	145	28	non	non	ADJ
admet-162	145	29	-	-	ADJ
admet-162	145	30	vascularized	vascularized	ADJ
admet-162	145	31	tumor	tumor	NOUN
admet-162	145	32	cells	cell	NOUN
admet-162	145	33	.	.	PUNCT
admet-162	146	1	heterogeneous	heterogeneous	ADJ
admet-162	146	2	distributions	distribution	NOUN
admet-162	146	3	for	for	ADP
admet-162	146	4	these	these	DET
admet-162	146	5	markers	marker	NOUN
admet-162	146	6	were	be	AUX
admet-162	146	7	detected	detect	VERB
admet-162	146	8	with	with	ADP
admet-162	146	9	differential	differential	ADJ
admet-162	146	10	immunostaining	immunostaining	NOUN
admet-162	146	11	pattern	pattern	NOUN
admet-162	146	12	,	,	PUNCT
admet-162	146	13	showing	show	VERB
admet-162	146	14	high	high	ADJ
admet-162	146	15	immunoreactivity	immunoreactivity	NOUN
admet-162	146	16	in	in	ADP
admet-162	146	17	sega	sega	NOUN
admet-162	146	18	cells	cell	NOUN
admet-162	146	19	far	far	ADV
admet-162	146	20	of	of	ADP
admet-162	146	21	vessels	vessel	NOUN
admet-162	146	22	,	,	PUNCT
admet-162	146	23	and	and	CCONJ
admet-162	146	24	low	low	ADJ
admet-162	146	25	or	or	CCONJ
admet-162	146	26	negative	negative	ADJ
admet-162	146	27	expression	expression	NOUN
admet-162	146	28	in	in	ADP
admet-162	146	29	sega	sega	NOUN
admet-162	146	30	cells	cell	NOUN
admet-162	146	31	near	near	ADP
admet-162	146	32	the	the	DET
admet-162	146	33	vessels	vessel	NOUN
admet-162	146	34	.	.	PUNCT
admet-162	147	1	this	this	DET
admet-162	147	2	particular	particular	ADJ
admet-162	147	3	expression	expression	NOUN
admet-162	147	4	pattern	pattern	NOUN
admet-162	147	5	of	of	ADP
admet-162	147	6	both	both	DET
admet-162	147	7	abc	abc	PROPN
admet-162	147	8	-	-	PUNCT
admet-162	147	9	transporters	transporter	NOUN
admet-162	147	10	,	,	PUNCT
admet-162	147	11	and	and	CCONJ
admet-162	147	12	cd34	cd34	PROPN
admet-162	147	13	antigen	antigen	NOUN
admet-162	147	14	could	could	AUX
admet-162	147	15	identify	identify	VERB
admet-162	147	16	different	different	ADJ
admet-162	147	17	stem	stem	NOUN
admet-162	147	18	-	-	PUNCT
admet-162	147	19	cell	cell	NOUN
admet-162	147	20	subset	subset	NOUN
admet-162	147	21	in	in	ADP
admet-162	147	22	sega	sega	NOUN
admet-162	147	23	[	[	X
admet-162	147	24	69	69	NUM
admet-162	147	25	]	]	PUNCT
admet-162	147	26	.	.	PUNCT
admet-162	148	1	similarly	similarly	ADV
admet-162	148	2	,	,	PUNCT
admet-162	148	3	co	co	NOUN
admet-162	148	4	-	-	NOUN
admet-162	148	5	expression	expression	NOUN
admet-162	148	6	of	of	ADP
admet-162	148	7	cd34	cd34	PROPN
admet-162	148	8	and	and	CCONJ
admet-162	148	9	neurofilament	neurofilament	NOUN
admet-162	148	10	were	be	AUX
admet-162	148	11	described	describe	VERB
admet-162	148	12	in	in	ADP
admet-162	148	13	epilepsy	epilepsy	NOUN
admet-162	148	14	-	-	PUNCT
admet-162	148	15	associated	associate	VERB
admet-162	148	16	glioneuronal	glioneuronal	ADJ
admet-162	148	17	tumors	tumor	NOUN
admet-162	149	1	[	[	X
admet-162	149	2	62,70	62,70	NOUN
admet-162	149	3	]	]	PUNCT
admet-162	149	4	.	.	PUNCT
admet-162	150	1	in	in	ADP
admet-162	150	2	normal	normal	ADJ
admet-162	150	3	brain	brain	NOUN
admet-162	150	4	,	,	PUNCT
admet-162	150	5	cd34	cd34	PROPN
admet-162	150	6	occurs	occur	VERB
admet-162	150	7	only	only	ADV
admet-162	150	8	transiently	transiently	ADV
admet-162	150	9	during	during	ADP
admet-162	150	10	neurulation	neurulation	NOUN
admet-162	150	11	[	[	X
admet-162	150	12	71	71	NUM
admet-162	150	13	]	]	PUNCT
admet-162	150	14	and	and	CCONJ
admet-162	150	15	recently	recently	ADV
admet-162	150	16	cd34	cd34	PROPN
admet-162	150	17	immunoreactivity	immunoreactivity	NOUN
admet-162	150	18	was	be	AUX
admet-162	150	19	also	also	ADV
admet-162	150	20	detected	detect	VERB
admet-162	150	21	as	as	ADP
admet-162	150	22	a	a	DET
admet-162	150	23	subpopulation	subpopulation	NOUN
admet-162	150	24	of	of	ADP
admet-162	150	25	balloon	balloon	NOUN
admet-162	150	26	cells	cell	NOUN
admet-162	150	27	confined	confine	VERB
admet-162	150	28	to	to	ADP
admet-162	150	29	the	the	DET
admet-162	150	30	white	white	ADJ
admet-162	150	31	matter	matter	NOUN
admet-162	150	32	but	but	CCONJ
admet-162	150	33	not	not	PART
admet-162	150	34	observed	observe	VERB
admet-162	150	35	in	in	ADP
admet-162	150	36	neocortical	neocortical	ADJ
admet-162	150	37	layers	layer	NOUN
admet-162	150	38	from	from	ADP
admet-162	150	39	brain	brain	NOUN
admet-162	150	40	specimens	specimen	NOUN
admet-162	150	41	of	of	ADP
admet-162	150	42	taylor	taylor	PROPN
admet-162	150	43	's	's	PART
admet-162	150	44	focal	focal	ADJ
admet-162	150	45	cortical	cortical	ADJ
admet-162	150	46	dysplasia	dysplasia	NOUN
admet-162	151	1	[	[	X
admet-162	151	2	72	72	NUM
admet-162	151	3	]	]	PUNCT
admet-162	151	4	.	.	PUNCT
admet-162	152	1	tissues	tissue	NOUN
admet-162	152	2	from	from	ADP
admet-162	152	3	therapeutic	therapeutic	ADJ
admet-162	152	4	resections	resection	NOUN
admet-162	152	5	of	of	ADP
admet-162	152	6	several	several	ADJ
admet-162	152	7	refractory	refractory	NOUN
admet-162	152	8	epilepsies	epilepsy	NOUN
admet-162	152	9	,	,	PUNCT
admet-162	152	10	as	as	ADP
admet-162	152	11	dysembryoplastic	dysembryoplastic	ADJ
admet-162	152	12	neuroepithelial	neuroepithelial	ADJ
admet-162	152	13	tumors	tumor	NOUN
admet-162	152	14	,	,	PUNCT
admet-162	152	15	focal	focal	ADJ
admet-162	152	16	cortical	cortical	ADJ
admet-162	152	17	dysplasia	dysplasia	NOUN
admet-162	152	18	and	and	CCONJ
admet-162	152	19	hippocampal	hippocampal	ADJ
admet-162	152	20	sclerosis	sclerosis	NOUN
admet-162	152	21	,	,	PUNCT
admet-162	152	22	as	as	ADV
admet-162	152	23	well	well	ADV
admet-162	152	24	as	as	ADP
admet-162	152	25	several	several	ADJ
admet-162	152	26	brain	brain	NOUN
admet-162	152	27	tumors	tumor	NOUN
admet-162	152	28	as	as	ADP
admet-162	152	29	glial	glial	ADJ
admet-162	152	30	and	and	CCONJ
admet-162	152	31	glioneuronal	glioneuronal	ADJ
admet-162	152	32	tumors	tumor	NOUN
admet-162	152	33	,	,	PUNCT
admet-162	152	34	are	be	AUX
admet-162	152	35	associated	associate	VERB
admet-162	152	36	with	with	ADP
admet-162	152	37	pharmacoresistant	pharmacoresistant	ADJ
admet-162	152	38	epilepsy	epilepsy	NOUN
admet-162	152	39	,	,	PUNCT
admet-162	152	40	having	have	VERB
admet-162	152	41	a	a	DET
admet-162	152	42	much	much	ADV
admet-162	152	43	poorer	poor	ADJ
admet-162	152	44	pharmacological	pharmacological	ADJ
admet-162	152	45	outcome	outcome	NOUN
admet-162	152	46	compared	compare	VERB
admet-162	152	47	to	to	ADP
admet-162	152	48	other	other	ADJ
admet-162	152	49	symptomatic	symptomatic	ADJ
admet-162	152	50	epilepsies	epilepsy	NOUN
admet-162	152	51	.	.	PUNCT
admet-162	153	1	in	in	ADP
admet-162	153	2	all	all	PRON
admet-162	153	3	of	of	ADP
admet-162	153	4	them	they	PRON
admet-162	153	5	,	,	PUNCT
admet-162	153	6	overexpression	overexpression	NOUN
admet-162	153	7	of	of	ADP
admet-162	153	8	abc	abc	PROPN
admet-162	153	9	-	-	PUNCT
admet-162	153	10	transporters	transporter	NOUN
admet-162	153	11	as	as	ADP
admet-162	153	12	p	p	NOUN
admet-162	153	13	-	-	PUNCT
admet-162	153	14	glycoprotein	glycoprotein	NOUN
admet-162	153	15	,	,	PUNCT
admet-162	153	16	mrps	mrps	PROPN
admet-162	153	17	and	and	CCONJ
admet-162	153	18	bcrp	bcrp	PROPN
admet-162	153	19	were	be	AUX
admet-162	153	20	described	describe	VERB
admet-162	153	21	[	[	X
admet-162	153	22	10,24,45,69,73	10,24,45,69,73	X
admet-162	153	23	]	]	PUNCT
admet-162	153	24	.	.	PUNCT
admet-162	154	1	abc	abc	PROPN
admet-162	154	2	-	-	PUNCT
admet-162	154	3	transporters	transporter	NOUN
admet-162	154	4	,	,	PUNCT
admet-162	154	5	particularly	particularly	ADV
admet-162	154	6	p	p	NOUN
admet-162	154	7	-	-	PUNCT
admet-162	154	8	gp	gp	NOUN
admet-162	154	9	and	and	CCONJ
admet-162	154	10	bcrp	bcrp	ADV
admet-162	154	11	,	,	PUNCT
admet-162	154	12	are	be	AUX
admet-162	154	13	transiently	transiently	ADV
admet-162	154	14	expressed	express	VERB
admet-162	154	15	at	at	ADP
admet-162	154	16	high	high	ADJ
admet-162	154	17	levels	level	NOUN
admet-162	154	18	in	in	ADP
admet-162	154	19	human	human	ADJ
admet-162	154	20	neural	neural	ADJ
admet-162	154	21	stem	stem	NOUN
admet-162	154	22	/	/	SYM
admet-162	154	23	progenitor	progenitor	NOUN
admet-162	154	24	cells	cell	NOUN
admet-162	154	25	(	(	PUNCT
admet-162	154	26	hnspcs	hnspcs	PROPN
admet-162	154	27	)	)	PUNCT
admet-162	154	28	but	but	CCONJ
admet-162	154	29	are	be	AUX
admet-162	154	30	downregulated	downregulate	VERB
admet-162	154	31	in	in	ADP
admet-162	154	32	differentiated	differentiated	ADJ
admet-162	154	33	hnspcs	hnspc	NOUN
admet-162	154	34	,	,	PUNCT
admet-162	154	35	and	and	CCONJ
admet-162	154	36	in	in	ADP
admet-162	154	37	normal	normal	ADJ
admet-162	154	38	conditions	condition	NOUN
admet-162	154	39	,	,	PUNCT
admet-162	154	40	they	they	PRON
admet-162	154	41	are	be	AUX
admet-162	154	42	expressed	express	VERB
admet-162	154	43	in	in	ADP
admet-162	154	44	a	a	DET
admet-162	154	45	highly	highly	ADV
admet-162	154	46	regulated	regulated	ADJ
admet-162	154	47	manner	manner	NOUN
admet-162	154	48	,	,	PUNCT
admet-162	154	49	with	with	ADP
admet-162	154	50	the	the	DET
admet-162	154	51	highest	high	ADJ
admet-162	154	52	expression	expression	NOUN
admet-162	154	53	in	in	ADP
admet-162	154	54	primitive	primitive	ADJ
admet-162	154	55	cells	cell	NOUN
admet-162	154	56	and	and	CCONJ
admet-162	154	57	subsequent	subsequent	ADJ
admet-162	154	58	down	down	ADJ
admet-162	154	59	-	-	PUNCT
admet-162	154	60	regulation	regulation	NOUN
admet-162	154	61	following	follow	VERB
admet-162	154	62	commitment	commitment	NOUN
admet-162	154	63	to	to	ADP
admet-162	154	64	differentiation	differentiation	NOUN
admet-162	154	65	[	[	X
admet-162	154	66	74	74	NUM
admet-162	154	67	]	]	PUNCT
admet-162	154	68	.	.	PUNCT
admet-162	155	1	furthermore	furthermore	ADV
admet-162	155	2	,	,	PUNCT
admet-162	155	3	the	the	DET
admet-162	155	4	constitutive	constitutive	ADJ
admet-162	155	5	deficiency	deficiency	NOUN
admet-162	155	6	of	of	ADP
admet-162	155	7	abc	abc	PROPN
admet-162	155	8	-	-	PUNCT
admet-162	155	9	transporters	transporter	NOUN
admet-162	155	10	leads	lead	VERB
admet-162	155	11	to	to	ADP
admet-162	155	12	distinct	distinct	ADJ
admet-162	155	13	impairments	impairment	NOUN
admet-162	155	14	in	in	ADP
admet-162	155	15	neural	neural	ADJ
admet-162	155	16	stem	stem	NOUN
admet-162	155	17	/	/	SYM
admet-162	155	18	progenitor	progenitor	NOUN
admet-162	155	19	cells	cell	NOUN
admet-162	155	20	maturation	maturation	NOUN
admet-162	155	21	and	and	CCONJ
admet-162	155	22	adult	adult	NOUN
admet-162	155	23	neurogenesis	neurogenesis	NOUN
admet-162	155	24	in	in	ADP
admet-162	155	25	vivo	vivo	NOUN
admet-162	155	26	,	,	PUNCT
admet-162	155	27	indicating	indicate	VERB
admet-162	155	28	a	a	DET
admet-162	155	29	functional	functional	ADJ
admet-162	155	30	role	role	NOUN
admet-162	155	31	of	of	ADP
admet-162	155	32	abc	abc	PROPN
admet-162	155	33	-	-	PUNCT
admet-162	155	34	transporters	transporter	NOUN
admet-162	155	35	in	in	ADP
admet-162	155	36	stem	stem	NOUN
admet-162	155	37	cell	cell	NOUN
admet-162	155	38	maintenance	maintenance	NOUN
admet-162	155	39	and	and	CCONJ
admet-162	155	40	differentiation	differentiation	NOUN
admet-162	155	41	[	[	X
admet-162	155	42	75	75	NUM
admet-162	155	43	]	]	PUNCT
admet-162	155	44	.	.	PUNCT
admet-162	156	1	all	all	DET
admet-162	156	2	these	these	DET
admet-162	156	3	data	datum	NOUN
admet-162	156	4	clearly	clearly	ADV
admet-162	156	5	suggests	suggest	VERB
admet-162	156	6	that	that	SCONJ
admet-162	156	7	presence	presence	NOUN
admet-162	156	8	of	of	ADP
admet-162	156	9	abc	abc	PROPN
admet-162	156	10	-	-	PUNCT
admet-162	156	11	transporters	transporter	NOUN
admet-162	156	12	,	,	PUNCT
admet-162	156	13	in	in	ADP
admet-162	156	14	abnormal	abnormal	ADJ
admet-162	156	15	and	and	CCONJ
admet-162	156	16	immature	immature	ADJ
admet-162	156	17	brain	brain	NOUN
admet-162	156	18	cells	cell	NOUN
admet-162	156	19	as	as	ADV
admet-162	156	20	well	well	ADV
admet-162	156	21	as	as	ADP
admet-162	156	22	in	in	ADP
admet-162	156	23	immortalized	immortalized	ADJ
admet-162	156	24	tumor	tumor	NOUN
admet-162	156	25	cells	cell	NOUN
admet-162	156	26	,	,	PUNCT
admet-162	156	27	are	be	AUX
admet-162	156	28	clearly	clearly	ADV
admet-162	156	29	a	a	DET
admet-162	156	30	hallmark	hallmark	NOUN
admet-162	156	31	of	of	ADP
admet-162	156	32	a	a	DET
admet-162	156	33	non	non	ADJ
admet-162	156	34	-	-	ADJ
admet-162	156	35	fully	fully	ADV
admet-162	156	36	differentiated	differentiated	ADJ
admet-162	156	37	progenitor	progenitor	NOUN
admet-162	156	38	cell	cell	NOUN
admet-162	156	39	.	.	PUNCT
admet-162	157	1	if	if	SCONJ
admet-162	157	2	it	it	PRON
admet-162	157	3	is	be	AUX
admet-162	157	4	the	the	DET
admet-162	157	5	case	case	NOUN
admet-162	157	6	,	,	PUNCT
admet-162	157	7	abc	abc	PROPN
admet-162	157	8	-	-	PUNCT
admet-162	157	9	transporters	transporter	NOUN
admet-162	157	10	together	together	ADV
admet-162	157	11	other	other	ADJ
admet-162	157	12	stem	stem	NOUN
admet-162	157	13	cell	cell	NOUN
admet-162	157	14	markers	marker	NOUN
admet-162	157	15	,	,	PUNCT
admet-162	157	16	could	could	AUX
admet-162	157	17	build	build	VERB
admet-162	157	18	a	a	DET
admet-162	157	19	new	new	ADJ
admet-162	157	20	biomarkers	biomarker	NOUN
admet-162	157	21	profile	profile	VERB
admet-162	157	22	to	to	PART
admet-162	157	23	give	give	VERB
admet-162	157	24	predictive	predictive	ADJ
admet-162	157	25	information	information	NOUN
admet-162	157	26	for	for	ADP
admet-162	157	27	long	long	ADJ
admet-162	157	28	-	-	PUNCT
admet-162	157	29	term	term	NOUN
admet-162	157	30	follow	follow	NOUN
admet-162	157	31	-	-	PUNCT
admet-162	157	32	up	up	NOUN
admet-162	157	33	of	of	ADP
admet-162	157	34	surgically	surgically	ADV
admet-162	157	35	treated	treat	VERB
admet-162	157	36	refractory	refractory	NOUN
admet-162	157	37	epilepsies	epilepsy	NOUN
admet-162	157	38	and/or	and/or	CCONJ
admet-162	157	39	related	relate	VERB
admet-162	157	40	with	with	ADP
admet-162	157	41	the	the	DET
admet-162	157	42	risk	risk	NOUN
admet-162	157	43	of	of	ADP
admet-162	157	44	relapse	relapse	NOUN
admet-162	157	45	of	of	ADP
admet-162	157	46	seizures	seizure	NOUN
admet-162	157	47	,	,	PUNCT
admet-162	157	48	even	even	ADV
admet-162	157	49	before	before	SCONJ
admet-162	157	50	that	that	SCONJ
admet-162	157	51	a	a	DET
admet-162	157	52	new	new	ADJ
admet-162	157	53	brain	brain	NOUN
admet-162	157	54	structural	structural	ADJ
admet-162	157	55	anomaly	anomaly	NOUN
admet-162	157	56	can	can	AUX
admet-162	157	57	be	be	AUX
admet-162	157	58	detected	detect	VERB
admet-162	157	59	.	.	PUNCT
admet-162	158	1	furthermore	furthermore	ADV
admet-162	158	2	,	,	PUNCT
admet-162	158	3	at	at	ADP
admet-162	158	4	date	date	NOUN
admet-162	158	5	,	,	PUNCT
admet-162	158	6	the	the	DET
admet-162	158	7	available	available	ADJ
admet-162	158	8	evidence	evidence	NOUN
admet-162	158	9	demonstrates	demonstrate	VERB
admet-162	158	10	that	that	SCONJ
admet-162	158	11	longterm	longterm	PROPN
admet-162	158	12	seizure	seizure	VERB
admet-162	158	13	freedom	freedom	NOUN
admet-162	158	14	is	be	AUX
admet-162	158	15	achieved	achieve	VERB
admet-162	158	16	in	in	ADP
admet-162	158	17	about	about	ADV
admet-162	158	18	60	60	NUM
admet-162	158	19	%	%	NOUN
admet-162	158	20	of	of	ADP
admet-162	158	21	patients	patient	NOUN
admet-162	158	22	who	who	PRON
admet-162	158	23	undergo	undergo	VERB
admet-162	158	24	temporal	temporal	ADJ
admet-162	158	25	lobe	lobe	ADJ
admet-162	158	26	surgery	surgery	NOUN
admet-162	158	27	,	,	PUNCT
admet-162	158	28	and	and	CCONJ
admet-162	158	29	in	in	ADP
admet-162	158	30	30	30	NUM
admet-162	158	31	–	–	PUNCT
admet-162	158	32	40	40	NUM
admet-162	158	33	%	%	NOUN
admet-162	158	34	of	of	ADP
admet-162	158	35	those	those	PRON
admet-162	158	36	who	who	PRON
admet-162	158	37	undergo	undergo	VERB
admet-162	158	38	extratemporal	extratemporal	ADJ
admet-162	158	39	surgery	surgery	NOUN
admet-162	158	40	[	[	X
admet-162	158	41	76	76	NUM
admet-162	158	42	]	]	PUNCT
admet-162	158	43	.	.	PUNCT
admet-162	159	1	conclusions	conclusion	NOUN
admet-162	159	2	it	it	PRON
admet-162	159	3	is	be	AUX
admet-162	159	4	important	important	ADJ
admet-162	159	5	to	to	PART
admet-162	159	6	distinguish	distinguish	VERB
admet-162	159	7	between	between	ADP
admet-162	159	8	the	the	DET
admet-162	159	9	truly	truly	ADV
admet-162	159	10	drug	drug	NOUN
admet-162	159	11	-	-	PUNCT
admet-162	159	12	transporter	transporter	NOUN
admet-162	159	13	properties	property	NOUN
admet-162	159	14	of	of	ADP
admet-162	159	15	these	these	DET
admet-162	159	16	proteins	protein	NOUN
admet-162	159	17	leading	lead	VERB
admet-162	159	18	to	to	ADP
admet-162	159	19	the	the	DET
admet-162	159	20	pharmacoresistant	pharmacoresistant	ADJ
admet-162	159	21	phenotype	phenotype	NOUN
admet-162	159	22	,	,	PUNCT
admet-162	159	23	from	from	ADP
admet-162	159	24	those	those	PRON
admet-162	159	25	related	relate	VERB
admet-162	159	26	with	with	ADP
admet-162	159	27	plasmatic	plasmatic	ADJ
admet-162	159	28	membrane	membrane	NOUN
admet-162	159	29	depolarization	depolarization	NOUN
admet-162	159	30	inducing	induce	VERB
admet-162	159	31	pro	pro	ADJ
admet-162	159	32	-	-	ADJ
admet-162	159	33	epileptic	epileptic	ADJ
admet-162	159	34	effects	effect	NOUN
admet-162	159	35	,	,	PUNCT
admet-162	159	36	directly	directly	ADV
admet-162	159	37	related	relate	VERB
admet-162	159	38	with	with	ADP
admet-162	159	39	epileptogenesis	epileptogenesis	NOUN
admet-162	159	40	as	as	SCONJ
admet-162	159	41	described	describe	VERB
admet-162	159	42	for	for	ADP
admet-162	159	43	p	p	NOUN
admet-162	159	44	-	-	PUNCT
admet-162	159	45	gp	gp	NOUN
admet-162	159	46	.	.	PUNCT
admet-162	160	1	in	in	ADP
admet-162	160	2	this	this	DET
admet-162	160	3	sense	sense	NOUN
admet-162	160	4	,	,	PUNCT
admet-162	160	5	abctransporters	abctransporter	NOUN
admet-162	160	6	,	,	PUNCT
admet-162	160	7	as	as	ADP
admet-162	160	8	p	p	NOUN
admet-162	160	9	-	-	PUNCT
admet-162	160	10	glycoprotein	glycoprotein	NOUN
admet-162	160	11	and	and	CCONJ
admet-162	160	12	bcrp	bcrp	ADV
admet-162	160	13	,	,	PUNCT
admet-162	160	14	could	could	AUX
admet-162	160	15	be	be	AUX
admet-162	160	16	interpreted	interpret	VERB
admet-162	160	17	as	as	ADP
admet-162	160	18	stem	stem	NOUN
admet-162	160	19	-	-	PUNCT
admet-162	160	20	cell	cell	NOUN
admet-162	160	21	markers	marker	NOUN
admet-162	160	22	presents	present	NOUN
admet-162	160	23	in	in	ADP
admet-162	160	24	several	several	ADJ
admet-162	160	25	brain	brain	NOUN
admet-162	160	26	cortical	cortical	ADJ
admet-162	160	27	malformations	malformation	NOUN
admet-162	160	28	,	,	PUNCT
admet-162	160	29	being	be	AUX
admet-162	160	30	constitutive	constitutive	ADJ
admet-162	160	31	components	component	NOUN
admet-162	160	32	of	of	ADP
admet-162	160	33	immature	immature	ADJ
admet-162	160	34	not	not	PART
admet-162	160	35	-	-	PUNCT
admet-162	160	36	fully	fully	ADV
admet-162	160	37	differentiated	differentiated	ADJ
admet-162	160	38	cells	cell	NOUN
admet-162	160	39	,	,	PUNCT
admet-162	160	40	as	as	SCONJ
admet-162	160	41	observed	observe	VERB
admet-162	160	42	in	in	ADP
admet-162	160	43	dysplastic	dysplastic	ADJ
admet-162	160	44	neurons	neuron	NOUN
admet-162	160	45	and	and	CCONJ
admet-162	160	46	ballooned	balloon	VERB
admet-162	160	47	cells	cell	NOUN
admet-162	160	48	or	or	CCONJ
admet-162	160	49	brain	brain	NOUN
admet-162	160	50	tumor	tumor	NOUN
admet-162	160	51	cells	cell	NOUN
admet-162	160	52	.	.	PUNCT
admet-162	161	1	interestingly	interestingly	ADV
admet-162	161	2	,	,	PUNCT
admet-162	161	3	all	all	DET
admet-162	161	4	these	these	DET
admet-162	161	5	abnormal	abnormal	ADJ
admet-162	161	6	cells	cell	NOUN
admet-162	161	7	that	that	PRON
admet-162	161	8	also	also	ADV
admet-162	161	9	play	play	VERB
admet-162	161	10	a	a	DET
admet-162	161	11	role	role	NOUN
admet-162	161	12	in	in	ADP
admet-162	161	13	the	the	DET
admet-162	161	14	epileptogenesis	epileptogenesis	NOUN
admet-162	161	15	,	,	PUNCT
admet-162	161	16	have	have	VERB
admet-162	161	17	high	high	ADJ
admet-162	161	18	expression	expression	NOUN
admet-162	161	19	of	of	ADP
admet-162	161	20	abc	abc	PROPN
admet-162	161	21	-	-	PUNCT
admet-162	161	22	transporters	transporter	NOUN
admet-162	161	23	and	and	CCONJ
admet-162	161	24	are	be	AUX
admet-162	161	25	also	also	ADV
admet-162	161	26	refractory	refractory	NOUN
admet-162	161	27	to	to	ADP
admet-162	161	28	aeds	aed	NOUN
admet-162	161	29	.	.	PUNCT
admet-162	162	1	under	under	ADP
admet-162	162	2	these	these	DET
admet-162	162	3	conditions	condition	NOUN
admet-162	162	4	,	,	PUNCT
admet-162	162	5	repetitive	repetitive	ADJ
admet-162	162	6	seizures	seizure	NOUN
admet-162	162	7	can	can	AUX
admet-162	162	8	induce	induce	VERB
admet-162	162	9	simultaneous	simultaneous	ADJ
admet-162	162	10	p	p	NOUN
admet-162	162	11	-	-	PUNCT
admet-162	162	12	gp	gp	NOUN
admet-162	162	13	overexpression	overexpression	NOUN
admet-162	162	14	in	in	ADP
admet-162	162	15	both	both	DET
admet-162	162	16	brain	brain	NOUN
admet-162	162	17	and	and	CCONJ
admet-162	162	18	heart	heart	NOUN
admet-162	162	19	.	.	PUNCT
admet-162	163	1	it	it	PRON
admet-162	163	2	could	could	AUX
admet-162	163	3	be	be	AUX
admet-162	163	4	a	a	DET
admet-162	163	5	combined	combined	ADJ
admet-162	163	6	risk	risk	NOUN
admet-162	163	7	factor	factor	NOUN
admet-162	163	8	to	to	PART
admet-162	163	9	develop	develop	VERB
admet-162	163	10	an	an	DET
admet-162	163	11	acute	acute	ADJ
admet-162	163	12	heart	heart	NOUN
admet-162	163	13	failure	failure	NOUN
admet-162	163	14	under	under	ADP
admet-162	163	15	severe	severe	ADJ
admet-162	163	16	stress	stress	NOUN
admet-162	163	17	triggered	trigger	VERB
admet-162	163	18	by	by	ADP
admet-162	163	19	status	status	NOUN
admet-162	163	20	epilepticus	epilepticus	NOUN
admet-162	163	21	resulting	result	VERB
admet-162	163	22	in	in	ADP
admet-162	163	23	a	a	DET
admet-162	163	24	fatal	fatal	ADJ
admet-162	163	25	end	end	NOUN
admet-162	163	26	.	.	PUNCT
admet-162	164	1	admet	admet	PROPN
admet-162	164	2	&	&	CCONJ
admet-162	164	3	dmpk	dmpk	PROPN
admet-162	164	4	3(2	3(2	NUM
admet-162	164	5	)	)	PUNCT
admet-162	164	6	(	(	PUNCT
admet-162	164	7	2015	2015	NUM
admet-162	164	8	)	)	PUNCT
admet-162	164	9	110	110	NUM
admet-162	164	10	-	-	SYM
admet-162	164	11	121	121	NUM
admet-162	164	12	the	the	DET
admet-162	164	13	roles	role	NOUN
admet-162	164	14	of	of	ADP
admet-162	164	15	p	p	NOUN
admet-162	164	16	-	-	PUNCT
admet-162	164	17	gp	gp	NOUN
admet-162	164	18	in	in	ADP
admet-162	164	19	refractory	refractory	NOUN
admet-162	164	20	epilepsy	epilepsy	NOUN
admet-162	164	21	doi	doi	NOUN
admet-162	164	22	:	:	PUNCT
admet-162	164	23	10.5599	10.5599	NUM
admet-162	164	24	/	/	SYM
admet-162	164	25	admet.3.2.162	admet.3.2.162	ADP
admet-162	164	26	119	119	NUM
admet-162	164	27	finally	finally	ADV
admet-162	164	28	,	,	PUNCT
admet-162	164	29	the	the	DET
admet-162	164	30	condition	condition	NOUN
admet-162	164	31	of	of	ADP
admet-162	164	32	abc	abc	PROPN
admet-162	164	33	-	-	PUNCT
admet-162	164	34	transporters	transporter	NOUN
admet-162	164	35	as	as	ADP
admet-162	164	36	stem	stem	NOUN
admet-162	164	37	cell	cell	NOUN
admet-162	164	38	markers	marker	NOUN
admet-162	164	39	,	,	PUNCT
admet-162	164	40	if	if	SCONJ
admet-162	164	41	they	they	PRON
admet-162	164	42	are	be	AUX
admet-162	164	43	presents	present	NOUN
admet-162	164	44	in	in	ADP
admet-162	164	45	those	those	DET
admet-162	164	46	mentioned	mention	VERB
admet-162	164	47	abnormal	abnormal	ADJ
admet-162	164	48	cells	cell	NOUN
admet-162	164	49	,	,	PUNCT
admet-162	164	50	could	could	AUX
admet-162	164	51	contribute	contribute	VERB
admet-162	164	52	to	to	PART
admet-162	164	53	build	build	VERB
admet-162	164	54	a	a	DET
admet-162	164	55	risk	risk	NOUN
admet-162	164	56	score	score	NOUN
admet-162	164	57	or	or	CCONJ
admet-162	164	58	predictive	predictive	ADJ
admet-162	164	59	profile	profile	NOUN
admet-162	164	60	for	for	ADP
admet-162	164	61	long	long	ADJ
admet-162	164	62	-	-	PUNCT
admet-162	164	63	time	time	NOUN
admet-162	164	64	seizures	seizure	NOUN
admet-162	164	65	relapse	relapse	VERB
admet-162	164	66	after	after	ADP
admet-162	164	67	surgical	surgical	ADJ
admet-162	164	68	treatment	treatment	NOUN
admet-162	164	69	.	.	PUNCT
admet-162	165	1	references	reference	NOUN
admet-162	165	2	[	[	X
admet-162	165	3	1	1	NUM
admet-162	165	4	]	]	X
admet-162	165	5	r.s	r.s	PROPN
admet-162	165	6	.	.	PROPN
admet-162	165	7	fisher	fisher	PROPN
admet-162	165	8	,	,	PUNCT
admet-162	165	9	c.	c.	PROPN
admet-162	165	10	acevedo	acevedo	PROPN
admet-162	165	11	,	,	PUNCT
admet-162	165	12	a.	a.	NOUN
admet-162	165	13	arzimanoglou	arzimanoglou	PROPN
admet-162	165	14	,	,	PUNCT
admet-162	165	15	a.	a.	NOUN
admet-162	165	16	bogacz	bogacz	NOUN
admet-162	165	17	,	,	PUNCT
admet-162	165	18	j.h	j.h	PROPN
admet-162	165	19	.	.	PROPN
admet-162	165	20	cross	cross	PROPN
admet-162	165	21	,	,	PUNCT
admet-162	165	22	c.e	c.e	PROPN
admet-162	165	23	.	.	PROPN
admet-162	165	24	elger	elger	PROPN
admet-162	165	25	,	,	PUNCT
admet-162	165	26	j.	j.	PROPN
admet-162	165	27	jr	jr	PROPN
admet-162	165	28	.	.	PUNCT
admet-162	166	1	engel	engel	PROPN
admet-162	166	2	,	,	PUNCT
admet-162	166	3	l.	l.	PROPN
admet-162	166	4	forsgren	forsgren	PROPN
admet-162	166	5	,	,	PUNCT
admet-162	166	6	j.a	j.a	PROPN
admet-162	166	7	.	.	PROPN
admet-162	166	8	french	french	PROPN
admet-162	166	9	,	,	PUNCT
admet-162	166	10	m.	m.	PROPN
admet-162	166	11	glynn	glynn	PROPN
admet-162	166	12	,	,	PUNCT
admet-162	166	13	d.c	d.c	PROPN
admet-162	166	14	.	.	PROPN
admet-162	166	15	hesdorffer	hesdorffer	PROPN
admet-162	166	16	,	,	PUNCT
admet-162	166	17	b.i	b.i	PROPN
admet-162	166	18	.	.	PROPN
admet-162	166	19	lee	lee	PROPN
admet-162	166	20	,	,	PUNCT
admet-162	166	21	g.w	g.w	PROPN
admet-162	166	22	.	.	PROPN
admet-162	166	23	mathern	mathern	PROPN
admet-162	166	24	,	,	PUNCT
admet-162	166	25	s.l	s.l	PROPN
admet-162	166	26	.	.	PROPN
admet-162	166	27	moshé	moshé	PROPN
admet-162	166	28	,	,	PUNCT
admet-162	166	29	e.	e.	PROPN
admet-162	166	30	perucca	perucca	PROPN
admet-162	166	31	,	,	PUNCT
admet-162	166	32	i.e.	i.e.	X
admet-162	166	33	scheffer	scheffer	NOUN
admet-162	166	34	,	,	PUNCT
admet-162	166	35	t.	t.	PROPN
admet-162	166	36	tomson	tomson	PROPN
admet-162	166	37	,	,	PUNCT
admet-162	166	38	m.	m.	PROPN
admet-162	166	39	watanabe	watanabe	PROPN
admet-162	166	40	,	,	PUNCT
admet-162	166	41	s.	s.	PROPN
admet-162	166	42	wiebe	wiebe	PROPN
admet-162	166	43	,	,	PUNCT
admet-162	166	44	epilepsia	epilepsia	NOUN
admet-162	166	45	55	55	NUM
admet-162	166	46	(	(	PUNCT
admet-162	166	47	2014	2014	NUM
admet-162	166	48	)	)	PUNCT
admet-162	166	49	475	475	NUM
admet-162	166	50	-	-	SYM
admet-162	166	51	482	482	NUM
admet-162	166	52	.	.	PUNCT
admet-162	167	1	[	[	X
admet-162	167	2	2	2	NUM
admet-162	167	3	]	]	X
admet-162	167	4	r.s	r.s	PROPN
admet-162	167	5	.	.	PROPN
admet-162	167	6	fisher	fisher	PROPN
admet-162	167	7	,	,	PUNCT
admet-162	167	8	epilepsia	epilepsia	NOUN
admet-162	167	9	55	55	NUM
admet-162	167	10	(	(	PUNCT
admet-162	167	11	2014	2014	NUM
admet-162	167	12	)	)	PUNCT
admet-162	167	13	492–493	492–493	NUM
admet-162	167	14	.	.	PUNCT
admet-162	168	1	[	[	X
admet-162	168	2	3	3	X
admet-162	168	3	]	]	X
admet-162	168	4	e.	e.	PROPN
admet-162	168	5	perucca	perucca	PROPN
admet-162	168	6	,	,	PUNCT
admet-162	168	7	epilepsia	epilepsia	NOUN
admet-162	168	8	55	55	NUM
admet-162	168	9	(	(	PUNCT
admet-162	168	10	2014	2014	NUM
admet-162	168	11	)	)	PUNCT
admet-162	168	12	473–474	473–474	NUM
admet-162	168	13	.	.	PUNCT
admet-162	169	1	[	[	X
admet-162	169	2	4	4	NUM
admet-162	169	3	]	]	X
admet-162	169	4	w.a	w.a	PROPN
admet-162	169	5	.	.	PROPN
admet-162	169	6	hauser	hauser	PROPN
admet-162	169	7	,	,	PUNCT
admet-162	169	8	incidence	incidence	NOUN
admet-162	169	9	and	and	CCONJ
admet-162	169	10	prevalence	prevalence	NOUN
admet-162	169	11	.	.	PUNCT
admet-162	170	1	in	in	ADP
admet-162	170	2	:	:	PUNCT
admet-162	170	3	j.	j.	PROPN
admet-162	170	4	engel	engel	PROPN
admet-162	170	5	jr	jr	PROPN
admet-162	170	6	,	,	PUNCT
admet-162	170	7	t.a	t.a	PROPN
admet-162	170	8	.	.	PROPN
admet-162	170	9	pedley	pedley	ADJ
admet-162	170	10	,	,	PUNCT
admet-162	170	11	editors	editor	NOUN
admet-162	170	12	.	.	PUNCT
admet-162	171	1	epilepsy	epilepsy	NOUN
admet-162	171	2	:	:	PUNCT
admet-162	171	3	a	a	DET
admet-162	171	4	comprehensive	comprehensive	ADJ
admet-162	171	5	textbook	textbook	NOUN
admet-162	171	6	.	.	PUNCT
admet-162	172	1	philadelphia	philadelphia	PROPN
admet-162	172	2	:	:	PUNCT
admet-162	172	3	lippincott	lippincott	PROPN
admet-162	172	4	–	–	PUNCT
admet-162	172	5	raven;1997	raven;1997	PROPN
admet-162	172	6	.	.	PUNCT
admet-162	172	7	p.47–57	p.47–57	PROPN
admet-162	173	1	[	[	X
admet-162	173	2	5	5	NUM
admet-162	173	3	]	]	PUNCT
admet-162	173	4	a.	a.	NOUN
admet-162	173	5	pitkänen	pitkänen	NOUN
admet-162	173	6	and	and	CCONJ
admet-162	173	7	k.	k.	PROPN
admet-162	173	8	lukasiuk	lukasiuk	PROPN
admet-162	173	9	,	,	PUNCT
admet-162	173	10	epilepsy	epilepsy	PROPN
admet-162	173	11	&	&	CCONJ
admet-162	173	12	behavior	behavior	PROPN
admet-162	173	13	14	14	NUM
admet-162	173	14	(	(	PUNCT
admet-162	173	15	2009	2009	NUM
admet-162	173	16	)	)	PUNCT
admet-162	173	17	16–25	16–25	NUM
admet-162	173	18	.	.	PUNCT
admet-162	174	1	[	[	X
admet-162	174	2	6	6	NUM
admet-162	174	3	]	]	PUNCT
admet-162	174	4	s.	s.	PROPN
admet-162	174	5	engelborghs	engelborghs	PROPN
admet-162	174	6	,	,	PUNCT
admet-162	174	7	r.	r.	PROPN
admet-162	174	8	d’hooge	d’hooge	PROPN
admet-162	174	9	,	,	PUNCT
admet-162	174	10	p.p	p.p	PROPN
admet-162	174	11	.	.	PROPN
admet-162	174	12	de	de	X
admet-162	174	13	deyn	deyn	PROPN
admet-162	174	14	,	,	PUNCT
admet-162	174	15	acta	acta	PROPN
admet-162	174	16	neurol	neurol	PROPN
admet-162	174	17	.	.	PUNCT
admet-162	175	1	belg	belg	PROPN
admet-162	175	2	.	.	PUNCT
admet-162	176	1	100	100	NUM
admet-162	176	2	(	(	PUNCT
admet-162	176	3	2000	2000	NUM
admet-162	176	4	)	)	PUNCT
admet-162	176	5	201	201	NUM
admet-162	176	6	-	-	SYM
admet-162	176	7	13	13	NUM
admet-162	176	8	.	.	PUNCT
admet-162	177	1	[	[	X
admet-162	177	2	7	7	X
admet-162	177	3	]	]	X
admet-162	177	4	b.	b.	PROPN
admet-162	177	5	bauer	bauer	PROPN
admet-162	177	6	,	,	PUNCT
admet-162	177	7	a.m.	a.m.	PROPN
admet-162	177	8	hartz	hartz	PROPN
admet-162	177	9	,	,	PUNCT
admet-162	177	10	a.	a.	NOUN
admet-162	177	11	pekcec	pekcec	PROPN
admet-162	177	12	,	,	PUNCT
admet-162	177	13	k.	k.	PROPN
admet-162	177	14	toellner	toellner	PROPN
admet-162	177	15	,	,	PUNCT
admet-162	177	16	d.s	d.s	PROPN
admet-162	177	17	.	.	PROPN
admet-162	177	18	miller	miller	PROPN
admet-162	177	19	,	,	PUNCT
admet-162	177	20	h.	h.	PROPN
admet-162	177	21	potschka	potschka	PROPN
admet-162	177	22	,	,	PUNCT
admet-162	177	23	mol	mol	PROPN
admet-162	177	24	.	.	PROPN
admet-162	177	25	pharmacol	pharmacol	PROPN
admet-162	177	26	.	.	PUNCT
admet-162	178	1	73	73	NUM
admet-162	178	2	(	(	PUNCT
admet-162	178	3	2008	2008	NUM
admet-162	178	4	)	)	PUNCT
admet-162	178	5	1444	1444	NUM
admet-162	178	6	-	-	SYM
admet-162	178	7	53	53	NUM
admet-162	178	8	.	.	PUNCT
admet-162	179	1	[	[	X
admet-162	179	2	8	8	NUM
admet-162	179	3	]	]	X
admet-162	179	4	r.w	r.w	PROPN
admet-162	179	5	.	.	PROPN
admet-162	179	6	robey	robey	PROPN
admet-162	179	7	,	,	PUNCT
admet-162	179	8	a.	a.	NOUN
admet-162	179	9	lazarowski	lazarowski	PROPN
admet-162	179	10	,	,	PUNCT
admet-162	179	11	s.e	s.e	PROPN
admet-162	179	12	.	.	PROPN
admet-162	179	13	bates	bates	PROPN
admet-162	179	14	,	,	PUNCT
admet-162	179	15	mol	mol	PROPN
admet-162	179	16	.	.	PROPN
admet-162	179	17	pharmacol	pharmacol	PROPN
admet-162	179	18	.	.	PUNCT
admet-162	180	1	73	73	NUM
admet-162	180	2	(	(	PUNCT
admet-162	180	3	2008	2008	NUM
admet-162	180	4	)	)	PUNCT
admet-162	180	5	1343	1343	NUM
admet-162	180	6	-	-	SYM
admet-162	180	7	6	6	NUM
admet-162	180	8	.	.	PUNCT
admet-162	181	1	[	[	X
admet-162	181	2	9	9	NUM
admet-162	181	3	]	]	PUNCT
admet-162	181	4	a.	a.	NOUN
admet-162	181	5	lazarowski	lazarowski	PROPN
admet-162	181	6	,	,	PUNCT
admet-162	181	7	l.	l.	PROPN
admet-162	181	8	czornyj	czornyj	PROPN
admet-162	181	9	,	,	PUNCT
admet-162	181	10	f.	f.	PROPN
admet-162	181	11	lubienieki	lubienieki	PROPN
admet-162	181	12	,	,	PUNCT
admet-162	181	13	e.	e.	PROPN
admet-162	181	14	girardi	girardi	PROPN
admet-162	181	15	,	,	PUNCT
admet-162	181	16	s.	s.	PROPN
admet-162	181	17	vazquez	vazquez	PROPN
admet-162	181	18	,	,	PUNCT
admet-162	181	19	c.	c.	PROPN
admet-162	181	20	d´giano	d´giano	NOUN
admet-162	181	21	,	,	PUNCT
admet-162	181	22	epilepsia	epilepsia	NOUN
admet-162	181	23	48	48	NUM
admet-162	181	24	(	(	PUNCT
admet-162	181	25	2007	2007	NUM
admet-162	181	26	)	)	PUNCT
admet-162	181	27	s5,140–149	s5,140–149	NOUN
admet-162	181	28	.	.	PUNCT
admet-162	182	1	[	[	X
admet-162	182	2	10	10	NUM
admet-162	182	3	]	]	X
admet-162	182	4	s.m	s.m	PROPN
admet-162	182	5	.	.	PROPN
admet-162	182	6	sisodiya	sisodiya	PROPN
admet-162	182	7	,	,	PUNCT
admet-162	182	8	w.r	w.r	PROPN
admet-162	182	9	.	.	PROPN
admet-162	182	10	lin	lin	PROPN
admet-162	182	11	,	,	PUNCT
admet-162	182	12	b.n	b.n	PROPN
admet-162	182	13	.	.	PROPN
admet-162	182	14	harding	harding	PROPN
admet-162	182	15	,	,	PUNCT
admet-162	182	16	m.v	m.v	PROPN
admet-162	182	17	.	.	PROPN
admet-162	182	18	squier	squier	PROPN
admet-162	182	19	,	,	PUNCT
admet-162	182	20	m.	m.	PROPN
admet-162	182	21	thom	thom	PROPN
admet-162	182	22	,	,	PUNCT
admet-162	182	23	brain	brain	NOUN
admet-162	182	24	125	125	NUM
admet-162	182	25	(	(	PUNCT
admet-162	182	26	2002	2002	NUM
admet-162	182	27	)	)	PUNCT
admet-162	182	28	22–31	22–31	NUM
admet-162	182	29	.	.	PUNCT
admet-162	183	1	[	[	X
admet-162	183	2	11	11	NUM
admet-162	183	3	]	]	PUNCT
admet-162	183	4	m.	m.	NOUN
admet-162	183	5	dean	dean	PROPN
admet-162	183	6	,	,	PUNCT
admet-162	183	7	y.	y.	PROPN
admet-162	183	8	hamon	hamon	PROPN
admet-162	183	9	,	,	PUNCT
admet-162	183	10	g.	g.	PROPN
admet-162	183	11	chimini	chimini	PROPN
admet-162	183	12	,	,	PUNCT
admet-162	183	13	j.	j.	PROPN
admet-162	183	14	lipid	lipid	PROPN
admet-162	183	15	res	re	NOUN
admet-162	183	16	.	.	PUNCT
admet-162	184	1	42	42	NUM
admet-162	184	2	(	(	PUNCT
admet-162	184	3	2001	2001	NUM
admet-162	184	4	)	)	PUNCT
admet-162	184	5	1007–17	1007–17	NUM
admet-162	184	6	.	.	PUNCT
admet-162	185	1	[	[	X
admet-162	185	2	12	12	NUM
admet-162	185	3	]	]	PUNCT
admet-162	185	4	m.	m.	NOUN
admet-162	185	5	dean	dean	PROPN
admet-162	185	6	,	,	PUNCT
admet-162	185	7	t.	t.	PROPN
admet-162	185	8	annilo	annilo	ADJ
admet-162	185	9	,	,	PUNCT
admet-162	185	10	annu	annu	PROPN
admet-162	185	11	.	.	PUNCT
admet-162	185	12	rev	rev	PROPN
admet-162	185	13	.	.	PROPN
admet-162	185	14	genomics	genomic	NOUN
admet-162	185	15	hum	hum	ADJ
admet-162	185	16	.	.	PUNCT
admet-162	186	1	genet	genet	NOUN
admet-162	186	2	.	.	PUNCT
admet-162	187	1	6	6	NUM
admet-162	187	2	(	(	PUNCT
admet-162	187	3	2005	2005	NUM
admet-162	187	4	)	)	PUNCT
admet-162	187	5	123–42	123–42	NUM
admet-162	187	6	.	.	PUNCT
admet-162	188	1	[	[	X
admet-162	188	2	13	13	NUM
admet-162	188	3	]	]	X
admet-162	188	4	m.m	m.m	PROPN
admet-162	188	5	.	.	PROPN
admet-162	188	6	gottesman	gottesman	PROPN
admet-162	188	7	,	,	PUNCT
admet-162	188	8	s.v	s.v	PROPN
admet-162	188	9	.	.	PROPN
admet-162	188	10	ambudkar	ambudkar	PROPN
admet-162	188	11	,	,	PUNCT
admet-162	188	12	j.	j.	PROPN
admet-162	188	13	bioenerg	bioenerg	PROPN
admet-162	188	14	.	.	PUNCT
admet-162	189	1	biomembr	biomembr	PROPN
admet-162	189	2	.	.	PUNCT
admet-162	190	1	33	33	NUM
admet-162	190	2	(	(	PUNCT
admet-162	190	3	2001	2001	NUM
admet-162	190	4	)	)	PUNCT
admet-162	190	5	453–8	453–8	X
admet-162	190	6	.	.	PUNCT
admet-162	191	1	[	[	X
admet-162	191	2	14	14	NUM
admet-162	191	3	]	]	X
admet-162	191	4	v.	v.	CCONJ
admet-162	191	5	ling	ling	PROPN
admet-162	191	6	,	,	PUNCT
admet-162	191	7	j.	j.	PROPN
admet-162	191	8	nat	nat	PROPN
admet-162	191	9	.	.	PUNCT
admet-162	192	1	cancer	cancer	NOUN
admet-162	192	2	inst	inst	PROPN
admet-162	192	3	.	.	PROPN
admet-162	193	1	81	81	NUM
admet-162	193	2	(	(	PUNCT
admet-162	193	3	1989	1989	NUM
admet-162	193	4	)	)	PUNCT
admet-162	193	5	84–85	84–85	NUM
admet-162	193	6	.	.	PUNCT
admet-162	194	1	[	[	X
admet-162	194	2	15	15	NUM
admet-162	194	3	]	]	X
admet-162	194	4	c.	c.	NOUN
admet-162	194	5	cordon	cordon	PROPN
admet-162	194	6	-	-	PUNCT
admet-162	194	7	cardo	cardo	NOUN
admet-162	194	8	,	,	PUNCT
admet-162	194	9	j.p	j.p	PROPN
admet-162	194	10	.	.	PROPN
admet-162	194	11	o’brien	o’brien	PROPN
admet-162	194	12	,	,	PUNCT
admet-162	194	13	j.	j.	PROPN
admet-162	194	14	boccia	boccia	PROPN
admet-162	194	15	,	,	PUNCT
admet-162	194	16	d.	d.	PROPN
admet-162	194	17	casals	casals	PROPN
admet-162	194	18	,	,	PUNCT
admet-162	194	19	j.r	j.r	PROPN
admet-162	194	20	.	.	PROPN
admet-162	194	21	bertino	bertino	PROPN
admet-162	194	22	,	,	PUNCT
admet-162	194	23	m.r.melamed	m.r.melame	VERB
admet-162	194	24	,	,	PUNCT
admet-162	194	25	j.	j.	PROPN
admet-162	194	26	histochem	histochem	PROPN
admet-162	194	27	.	.	PUNCT
admet-162	195	1	cytochem	cytochem	PROPN
admet-162	195	2	.	.	PUNCT
admet-162	196	1	138	138	NUM
admet-162	196	2	(	(	PUNCT
admet-162	196	3	1990	1990	NUM
admet-162	196	4	)	)	PUNCT
admet-162	196	5	1277–1287	1277–1287	NUM
admet-162	196	6	.	.	PUNCT
admet-162	197	1	[	[	X
admet-162	197	2	16	16	NUM
admet-162	197	3	]	]	X
admet-162	197	4	m.m	m.m	PROPN
admet-162	197	5	.	.	PROPN
admet-162	197	6	gottesman	gottesman	PROPN
admet-162	197	7	,	,	PUNCT
admet-162	197	8	t.	t.	NOUN
admet-162	197	9	fojo	fojo	NOUN
admet-162	197	10	,	,	PUNCT
admet-162	197	11	s.e	s.e	PROPN
admet-162	197	12	.	.	PROPN
admet-162	197	13	bates	bates	PROPN
admet-162	197	14	,	,	PUNCT
admet-162	197	15	nat	nat	PROPN
admet-162	197	16	.	.	PUNCT
admet-162	197	17	rev	rev	PROPN
admet-162	197	18	.	.	PUNCT
admet-162	198	1	cancer	cancer	NOUN
admet-162	198	2	2	2	NUM
admet-162	198	3	(	(	PUNCT
admet-162	198	4	2002	2002	NUM
admet-162	198	5	)	)	PUNCT
admet-162	198	6	48–58	48–58	NUM
admet-162	198	7	.	.	PUNCT
admet-162	199	1	[	[	X
admet-162	199	2	17	17	NUM
admet-162	199	3	]	]	X
admet-162	199	4	c.f	c.f	PROPN
admet-162	199	5	.	.	PROPN
admet-162	199	6	higgins	higgins	PROPN
admet-162	199	7	,	,	PUNCT
admet-162	199	8	i.d	i.d	PROPN
admet-162	199	9	.	.	PROPN
admet-162	199	10	hiles	hile	NOUN
admet-162	199	11	,	,	PUNCT
admet-162	200	1	g.p.c	g.p.c	ADJ
admet-162	200	2	.	.	PUNCT
admet-162	200	3	salmond	salmond	PROPN
admet-162	200	4	,	,	PUNCT
admet-162	200	5	d.r	d.r	PROPN
admet-162	200	6	.	.	PROPN
admet-162	200	7	gill	gill	PROPN
admet-162	200	8	,	,	PUNCT
admet-162	200	9	j.a	j.a	PROPN
admet-162	200	10	.	.	PROPN
admet-162	200	11	downie	downie	PROPN
admet-162	200	12	,	,	PUNCT
admet-162	200	13	i.j	i.j	PROPN
admet-162	200	14	.	.	PROPN
admet-162	200	15	evans	evans	PROPN
admet-162	200	16	,	,	PUNCT
admet-162	200	17	i.b	i.b	PROPN
admet-162	200	18	.	.	PROPN
admet-162	200	19	holland	holland	PROPN
admet-162	200	20	,	,	PUNCT
admet-162	200	21	l.	l.	PROPN
admet-162	200	22	gray	gray	PROPN
admet-162	200	23	,	,	PUNCT
admet-162	200	24	s.d	s.d	PROPN
admet-162	200	25	.	.	PROPN
admet-162	200	26	buckel	buckel	PROPN
admet-162	200	27	,	,	PUNCT
admet-162	200	28	a.w	a.w	PROPN
admet-162	200	29	.	.	PROPN
admet-162	200	30	bell	bell	PROPN
admet-162	200	31	,	,	PUNCT
admet-162	200	32	m.a	m.a	PROPN
admet-162	200	33	.	.	PROPN
admet-162	200	34	hermodson	hermodson	PROPN
admet-162	200	35	,	,	PUNCT
admet-162	200	36	nature	nature	NOUN
admet-162	200	37	323	323	NUM
admet-162	200	38	(	(	PUNCT
admet-162	200	39	1986	1986	NUM
admet-162	200	40	)	)	PUNCT
admet-162	200	41	448–50	448–50	NOUN
admet-162	200	42	.	.	PUNCT
admet-162	201	1	[	[	X
admet-162	201	2	18	18	NUM
admet-162	201	3	]	]	X
admet-162	201	4	a.l	a.l	PROPN
admet-162	201	5	.	.	PROPN
admet-162	201	6	davidson	davidson	PROPN
admet-162	201	7	,	,	PUNCT
admet-162	201	8	j.	j.	PROPN
admet-162	201	9	bacteriol	bacteriol	PROPN
admet-162	201	10	.	.	PUNCT
admet-162	202	1	184	184	NUM
admet-162	202	2	(	(	PUNCT
admet-162	202	3	2002	2002	NUM
admet-162	202	4	)	)	PUNCT
admet-162	202	5	1225–33	1225–33	NUM
admet-162	202	6	.	.	PUNCT
admet-162	203	1	[	[	X
admet-162	203	2	19	19	NUM
admet-162	203	3	]	]	X
admet-162	203	4	c.f	c.f	PROPN
admet-162	203	5	.	.	PROPN
admet-162	203	6	higgins	higgins	PROPN
admet-162	203	7	,	,	PUNCT
admet-162	203	8	k.j	k.j	PROPN
admet-162	203	9	.	.	PROPN
admet-162	203	10	linton	linton	PROPN
admet-162	203	11	,	,	PUNCT
admet-162	203	12	nat	nat	PROPN
admet-162	203	13	.	.	PUNCT
admet-162	203	14	struct	struct	NOUN
admet-162	203	15	.	.	PUNCT
admet-162	204	1	mol	mol	PROPN
admet-162	204	2	.	.	PUNCT
admet-162	205	1	biol	biol	PROPN
admet-162	205	2	.	.	PUNCT
admet-162	206	1	11	11	NUM
admet-162	206	2	(	(	PUNCT
admet-162	206	3	2004	2004	NUM
admet-162	206	4	)	)	PUNCT
admet-162	206	5	918–26	918–26	NOUN
admet-162	206	6	.	.	PUNCT
admet-162	207	1	[	[	X
admet-162	207	2	20	20	NUM
admet-162	207	3	]	]	X
admet-162	207	4	z.e	z.e	PROPN
admet-162	207	5	.	.	PROPN
admet-162	207	6	sauna	sauna	PROPN
admet-162	207	7	,	,	PUNCT
admet-162	207	8	s.v	s.v	PROPN
admet-162	207	9	.	.	PROPN
admet-162	207	10	ambudkar	ambudkar	PROPN
admet-162	207	11	,	,	PUNCT
admet-162	207	12	mol	mol	PROPN
admet-162	207	13	.	.	PUNCT
admet-162	208	1	cancer	cancer	NOUN
admet-162	208	2	ther	ther	PROPN
admet-162	208	3	.	.	PUNCT
admet-162	209	1	6	6	NUM
admet-162	209	2	(	(	PUNCT
admet-162	209	3	2007	2007	NUM
admet-162	209	4	)	)	PUNCT
admet-162	209	5	13	13	NUM
admet-162	209	6	-	-	SYM
admet-162	209	7	23	23	NUM
admet-162	209	8	.	.	PUNCT
admet-162	210	1	[	[	X
admet-162	210	2	21	21	NUM
admet-162	210	3	]	]	X
admet-162	210	4	s.m	s.m	PROPN
admet-162	210	5	.	.	PROPN
admet-162	210	6	sisodiya	sisodiya	PROPN
admet-162	210	7	,	,	PUNCT
admet-162	210	8	epilepsia	epilepsia	NOUN
admet-162	210	9	46	46	NUM
admet-162	210	10	(	(	PUNCT
admet-162	210	11	2005	2005	NUM
admet-162	210	12	)	)	PUNCT
admet-162	210	13	(	(	PUNCT
admet-162	210	14	suppl	suppl	ADJ
admet-162	210	15	10	10	NUM
admet-162	210	16	)	)	PUNCT
admet-162	210	17	33–8	33–8	NUM
admet-162	210	18	.	.	PUNCT
admet-162	211	1	[	[	X
admet-162	211	2	22	22	NUM
admet-162	211	3	]	]	X
admet-162	211	4	d.	d.	PROPN
admet-162	211	5	tishler	tishler	PROPN
admet-162	211	6	,	,	PUNCT
admet-162	211	7	k.	k.	PROPN
admet-162	211	8	weinberg	weinberg	PROPN
admet-162	211	9	,	,	PUNCT
admet-162	211	10	d.	d.	PROPN
admet-162	211	11	hinton	hinton	PROPN
admet-162	211	12	,	,	PUNCT
admet-162	211	13	n.	n.	PROPN
admet-162	211	14	barbaro	barbaro	PROPN
admet-162	211	15	,	,	PUNCT
admet-162	211	16	a.	a.	NOUN
admet-162	211	17	geralyn	geralyn	PROPN
admet-162	211	18	,	,	PUNCT
admet-162	211	19	r.	r.	PROPN
admet-162	211	20	corey	corey	PROPN
admet-162	211	21	,	,	PUNCT
admet-162	211	22	epilepsia	epilepsia	NOUN
admet-162	211	23	36	36	NUM
admet-162	211	24	(	(	PUNCT
admet-162	211	25	1995	1995	NUM
admet-162	211	26	)	)	PUNCT
admet-162	211	27	1	1	NUM
admet-162	211	28	-	-	SYM
admet-162	211	29	6	6	NUM
admet-162	211	30	.	.	PUNCT
admet-162	212	1	[	[	X
admet-162	212	2	23	23	NUM
admet-162	212	3	]	]	PUNCT
admet-162	212	4	a.	a.	NOUN
admet-162	212	5	lazarowski	lazarowski	PROPN
admet-162	212	6	,	,	PUNCT
admet-162	212	7	g.	g.	PROPN
admet-162	212	8	sevlever	sevlever	PROPN
admet-162	212	9	,	,	PUNCT
admet-162	212	10	a.	a.	NOUN
admet-162	212	11	taratuto	taratuto	PROPN
admet-162	212	12	,	,	PUNCT
admet-162	212	13	m.	m.	NOUN
admet-162	212	14	massaro	massaro	PROPN
admet-162	212	15	,	,	PUNCT
admet-162	212	16	a.	a.	NOUN
admet-162	212	17	rabinowicz	rabinowicz	PROPN
admet-162	212	18	,	,	PUNCT
admet-162	212	19	ped	ped	NOUN
admet-162	212	20	.	.	PUNCT
admet-162	213	1	neurol	neurol	PROPN
admet-162	213	2	.	.	PUNCT
admet-162	214	1	21	21	NUM
admet-162	214	2	(	(	PUNCT
admet-162	214	3	1999	1999	NUM
admet-162	214	4	)	)	PUNCT
admet-162	214	5	731	731	NUM
admet-162	214	6	-	-	SYM
admet-162	214	7	734	734	NUM
admet-162	214	8	.	.	PUNCT
admet-162	215	1	[	[	X
admet-162	215	2	24	24	NUM
admet-162	215	3	]	]	X
admet-162	215	4	a.j	a.j	PROPN
admet-162	215	5	.	.	PROPN
admet-162	215	6	lazarowski	lazarowski	PROPN
admet-162	215	7	,	,	PUNCT
admet-162	215	8	f.j	f.j	PROPN
admet-162	215	9	.	.	PROPN
admet-162	215	10	lubieniecki	lubieniecki	PROPN
admet-162	215	11	,	,	PUNCT
admet-162	215	12	s.a	s.a	PROPN
admet-162	215	13	.	.	PROPN
admet-162	215	14	camarero	camarero	PROPN
admet-162	215	15	,	,	PUNCT
admet-162	215	16	h.h	h.h	PROPN
admet-162	215	17	.	.	PROPN
admet-162	215	18	pomata	pomata	NOUN
admet-162	215	19	,	,	PUNCT
admet-162	215	20	m.a	m.a	PROPN
admet-162	215	21	.	.	PROPN
admet-162	215	22	bartuluchi	bartuluchi	PROPN
admet-162	215	23	,	,	PUNCT
admet-162	215	24	g.	g.	PROPN
admet-162	215	25	sevlever	sevlever	PROPN
admet-162	215	26	,	,	PUNCT
admet-162	215	27	a.l	a.l	PROPN
admet-162	215	28	.	.	PROPN
admet-162	215	29	taratuto	taratuto	NOUN
admet-162	215	30	.	.	PUNCT
admet-162	216	1	pediatr	pediatr	PROPN
admet-162	216	2	.	.	PUNCT
admet-162	217	1	neurol	neurol	NOUN
admet-162	217	2	.	.	PUNCT
admet-162	218	1	34	34	NUM
admet-162	218	2	(	(	PUNCT
admet-162	218	3	2006	2006	NUM
admet-162	218	4	)	)	PUNCT
admet-162	218	5	20	20	NUM
admet-162	218	6	-	-	SYM
admet-162	218	7	4	4	NUM
admet-162	218	8	.	.	PUNCT
admet-162	219	1	[	[	X
admet-162	219	2	25	25	NUM
admet-162	219	3	]	]	PUNCT
admet-162	219	4	l.	l.	PROPN
admet-162	219	5	zhang	zhang	PROPN
admet-162	219	6	,	,	PUNCT
admet-162	219	7	w.	w.	PROPN
admet-162	219	8	ong	ong	PROPN
admet-162	219	9	,	,	PUNCT
admet-162	219	10	t.	t.	PROPN
admet-162	219	11	lee	lee	PROPN
admet-162	219	12	,	,	PUNCT
admet-162	219	13	exp	exp	PROPN
admet-162	219	14	.	.	PUNCT
admet-162	219	15	brain	brain	NOUN
admet-162	219	16	res	re	NOUN
admet-162	219	17	.	.	PUNCT
admet-162	220	1	126	126	NUM
admet-162	220	2	(	(	PUNCT
admet-162	220	3	1999	1999	NUM
admet-162	220	4	)	)	PUNCT
admet-162	220	5	509	509	NUM
admet-162	220	6	-	-	SYM
admet-162	220	7	516	516	NUM
admet-162	220	8	.	.	PUNCT
admet-162	221	1	[	[	X
admet-162	221	2	26	26	NUM
admet-162	221	3	]	]	X
admet-162	221	4	u.	u.	NOUN
admet-162	221	5	seegers	seeger	NOUN
admet-162	221	6	,	,	PUNCT
admet-162	221	7	h.	h.	PROPN
admet-162	221	8	potschka	potschka	PROPN
admet-162	221	9	,	,	PUNCT
admet-162	221	10	w.	w.	PROPN
admet-162	221	11	loscher	loscher	PROPN
admet-162	221	12	,	,	PUNCT
admet-162	221	13	epilepsia	epilepsia	NOUN
admet-162	221	14	43	43	NUM
admet-162	221	15	(	(	PUNCT
admet-162	221	16	2002	2002	NUM
admet-162	221	17	)	)	PUNCT
admet-162	221	18	675	675	NUM
admet-162	221	19	-	-	SYM
admet-162	221	20	684	684	NUM
admet-162	221	21	.	.	PUNCT
admet-162	222	1	[	[	X
admet-162	222	2	27	27	NUM
admet-162	222	3	]	]	PUNCT
admet-162	222	4	m.	m.	NOUN
admet-162	222	5	rizzi	rizzi	PROPN
admet-162	222	6	,	,	PUNCT
admet-162	222	7	s.	s.	PROPN
admet-162	222	8	caccia	caccia	PROPN
admet-162	222	9	,	,	PUNCT
admet-162	222	10	g.	g.	PROPN
admet-162	222	11	guiso	guiso	PROPN
admet-162	222	12	,	,	PUNCT
admet-162	222	13	c.	c.	PROPN
admet-162	222	14	richichi	richichi	PROPN
admet-162	222	15	,	,	PUNCT
admet-162	222	16	j.a	j.a	PROPN
admet-162	222	17	.	.	PROPN
admet-162	222	18	gorter	gorter	PROPN
admet-162	222	19	,	,	PUNCT
admet-162	222	20	e.	e.	PROPN
admet-162	222	21	aronica	aronica	PROPN
admet-162	222	22	,	,	PUNCT
admet-162	222	23	m.	m.	NOUN
admet-162	222	24	aliprandi	aliprandi	PROPN
admet-162	222	25	,	,	PUNCT
admet-162	222	26	r.	r.	PROPN
admet-162	222	27	bagnati	bagnati	PROPN
admet-162	222	28	,	,	PUNCT
admet-162	222	29	r.	r.	PROPN
admet-162	222	30	fanelli	fanelli	PROPN
admet-162	222	31	,	,	PUNCT
admet-162	222	32	m.	m.	NOUN
admet-162	222	33	d'incalci	d'incalci	PROPN
admet-162	222	34	,	,	PUNCT
admet-162	222	35	r.	r.	PROPN
admet-162	222	36	samanin	samanin	PROPN
admet-162	222	37	,	,	PUNCT
admet-162	222	38	a.	a.	NOUN
admet-162	222	39	vezzani	vezzani	PROPN
admet-162	222	40	,	,	PUNCT
admet-162	222	41	j.	j.	PROPN
admet-162	222	42	neurosc	neurosc	PROPN
admet-162	222	43	.	.	PUNCT
admet-162	223	1	22	22	NUM
admet-162	223	2	(	(	PUNCT
admet-162	223	3	2002	2002	NUM
admet-162	223	4	)	)	PUNCT
admet-162	223	5	5833	5833	NUM
admet-162	223	6	-	-	SYM
admet-162	223	7	5839	5839	NUM
admet-162	223	8	.	.	PUNCT
admet-162	224	1	[	[	X
admet-162	224	2	28	28	NUM
admet-162	224	3	]	]	X
admet-162	224	4	p.	p.	PROPN
admet-162	224	5	kwan	kwan	PROPN
admet-162	224	6	,	,	PUNCT
admet-162	224	7	g.	g.	PROPN
admet-162	224	8	still	still	ADV
admet-162	224	9	,	,	PUNCT
admet-162	224	10	e.	e.	PROPN
admet-162	224	11	butler	butler	PROPN
admet-162	224	12	,	,	PUNCT
admet-162	224	13	t.	t.	PROPN
admet-162	224	14	gant	gant	PROPN
admet-162	224	15	,	,	PUNCT
admet-162	224	16	b.	b.	PROPN
admet-162	224	17	meldrum	meldrum	PROPN
admet-162	224	18	,	,	PUNCT
admet-162	224	19	m.	m.	PROPN
admet-162	224	20	brodie	brodie	PROPN
admet-162	224	21	,	,	PUNCT
admet-162	224	22	epilepsy	epilepsy	VERB
admet-162	224	23	43	43	NUM
admet-162	224	24	(	(	PUNCT
admet-162	224	25	2002	2002	NUM
admet-162	224	26	)	)	PUNCT
admet-162	224	27	1318	1318	NUM
admet-162	224	28	-	-	SYM
admet-162	224	29	1323	1323	NUM
admet-162	224	30	.	.	PUNCT
admet-162	225	1	[	[	X
admet-162	225	2	29	29	NUM
admet-162	225	3	]	]	PUNCT
admet-162	225	4	a.	a.	NOUN
admet-162	225	5	lazarowski	lazarowski	PROPN
admet-162	225	6	,	,	PUNCT
admet-162	225	7	a.j	a.j	PROPN
admet-162	225	8	.	.	PROPN
admet-162	225	9	ramos	ramos	PROPN
admet-162	225	10	,	,	PUNCT
admet-162	225	11	h.	h.	PROPN
admet-162	225	12	garcía	garcía	PROPN
admet-162	225	13	-	-	PUNCT
admet-162	225	14	rivello	rivello	NOUN
admet-162	225	15	,	,	PUNCT
admet-162	225	16	e.	e.	PROPN
admet-162	225	17	girardi	girardi	PROPN
admet-162	225	18	,	,	PUNCT
admet-162	225	19	cell	cell	NOUN
admet-162	225	20	mol	mol	PROPN
admet-162	225	21	.	.	PUNCT
admet-162	226	1	neurobiol	neurobiol	PROPN
admet-162	226	2	.24	.24	NUM
admet-162	226	3	(	(	PUNCT
admet-162	226	4	2004	2004	NUM
admet-162	226	5	)	)	PUNCT
admet-162	226	6	77	77	NUM
admet-162	226	7	-	-	SYM
admet-162	226	8	85	85	NUM
admet-162	226	9	.	.	PUNCT
admet-162	227	1	[	[	X
admet-162	227	2	30	30	NUM
admet-162	227	3	]	]	X
admet-162	227	4	e.a	e.a	PROPN
admet-162	227	5	.	.	PROPN
admet-162	227	6	van	van	PROPN
admet-162	227	7	vliet	vliet	PROPN
admet-162	227	8	,	,	PUNCT
admet-162	227	9	r.	r.	PROPN
admet-162	227	10	van	van	PROPN
admet-162	227	11	schaik	schaik	PROPN
admet-162	227	12	,	,	PUNCT
admet-162	227	13	p.m.	p.m.	NOUN
admet-162	227	14	edelbroek	edelbroek	NOUN
admet-162	227	15	,	,	PUNCT
admet-162	227	16	r.a	r.a	PROPN
admet-162	227	17	.	.	PROPN
admet-162	227	18	voskuyl	voskuyl	PROPN
admet-162	227	19	,	,	PUNCT
admet-162	227	20	s.	s.	PROPN
admet-162	227	21	redeker	redeker	PROPN
admet-162	227	22	,	,	PUNCT
admet-162	227	23	e.	e.	PROPN
admet-162	227	24	aronica	aronica	PROPN
admet-162	227	25	,	,	PUNCT
admet-162	227	26	w.j	w.j	PROPN
admet-162	227	27	.	.	PROPN
admet-162	227	28	wadman	wadman	PROPN
admet-162	227	29	,	,	PUNCT
admet-162	227	30	j.a	j.a	PROPN
admet-162	227	31	.	.	PROPN
admet-162	227	32	gorter	gorter	PROPN
admet-162	227	33	,	,	PUNCT
admet-162	227	34	jpet	jpet	NOUN
admet-162	227	35	322	322	NUM
admet-162	227	36	(	(	PUNCT
admet-162	227	37	2007	2007	NUM
admet-162	227	38	)	)	PUNCT
admet-162	227	39	141–147	141–147	NUM
admet-162	227	40	.	.	PUNCT
admet-162	228	1	lazarowski	lazarowski	PROPN
admet-162	228	2	et	et	PROPN
admet-162	228	3	al	al	PROPN
admet-162	228	4	.	.	PROPN
admet-162	228	5	admet	admet	PROPN
admet-162	228	6	&	&	CCONJ
admet-162	228	7	dmpk	dmpk	PROPN
admet-162	228	8	3(2	3(2	NUM
admet-162	228	9	)	)	PUNCT
admet-162	228	10	(	(	PUNCT
admet-162	228	11	2015	2015	NUM
admet-162	228	12	)	)	PUNCT
admet-162	228	13	110	110	NUM
admet-162	228	14	-	-	SYM
admet-162	228	15	121	121	NUM
admet-162	228	16	120	120	NUM
admet-162	228	17	[	[	X
admet-162	228	18	31	31	NUM
admet-162	228	19	]	]	PUNCT
admet-162	228	20	j.	j.	PROPN
admet-162	228	21	auzmendi	auzmendi	PROPN
admet-162	228	22	,	,	PUNCT
admet-162	228	23	a.	a.	NOUN
admet-162	228	24	merelli	merelli	PROPN
admet-162	228	25	,	,	PUNCT
admet-162	228	26	e.	e.	PROPN
admet-162	228	27	girardi	girardi	PROPN
admet-162	228	28	,	,	PUNCT
admet-162	228	29	s.	s.	PROPN
admet-162	228	30	orozco	orozco	PROPN
admet-162	228	31	-	-	PUNCT
admet-162	228	32	suarez	suarez	PROPN
admet-162	228	33	,	,	PUNCT
admet-162	228	34	l	l	PROPN
admet-162	228	35	rocha	rocha	PROPN
admet-162	228	36	,	,	PUNCT
admet-162	228	37	a.	a.	NOUN
admet-162	228	38	lazarowski	lazarowski	PROPN
admet-162	228	39	,	,	PUNCT
admet-162	228	40	mol	mol	PROPN
admet-162	228	41	.	.	PROPN
admet-162	228	42	cell	cell	NOUN
admet-162	228	43	epilepsy	epilepsy	NOUN
admet-162	228	44	1	1	NUM
admet-162	228	45	(	(	PUNCT
admet-162	228	46	2014	2014	NUM
admet-162	228	47	)	)	PUNCT
admet-162	228	48	3:1	3:1	NUM
admet-162	228	49	-	-	SYM
admet-162	228	50	9	9	NUM
admet-162	228	51	.	.	PUNCT
admet-162	229	1	[	[	X
admet-162	229	2	32	32	NUM
admet-162	229	3	]	]	SYM
admet-162	229	4	a.l	a.l	PROPN
admet-162	229	5	.	.	PROPN
admet-162	229	6	rabinowicz	rabinowicz	PROPN
admet-162	229	7	,	,	PUNCT
admet-162	229	8	j.m	j.m	PROPN
admet-162	229	9	.	.	PROPN
admet-162	229	10	salvat	salvat	PROPN
admet-162	229	11	,	,	PUNCT
admet-162	229	12	r.c	r.c	PROPN
admet-162	229	13	.	.	PROPN
admet-162	229	14	leiguarda	leiguarda	PROPN
admet-162	229	15	,	,	PUNCT
admet-162	229	16	f.	f.	PROPN
admet-162	229	17	demonty	demonty	PROPN
admet-162	229	18	,	,	PUNCT
admet-162	229	19	f.	f.	PROPN
admet-162	229	20	salvat	salvat	PROPN
admet-162	229	21	,	,	PUNCT
admet-162	229	22	a.	a.	NOUN
admet-162	229	23	cervio	cervio	NOUN
admet-162	229	24	,	,	PUNCT
admet-162	229	25	f.	f.	PROPN
admet-162	229	26	manes	manes	PROPN
admet-162	229	27	,	,	PUNCT
admet-162	229	28	a.	a.	NOUN
admet-162	229	29	lazarowski	lazarowski	NOUN
admet-162	229	30	.	.	PUNCT
admet-162	230	1	clin	clin	PROPN
admet-162	230	2	.	.	PUNCT
admet-162	231	1	neuropharmacol	neuropharmacol	PROPN
admet-162	231	2	.	.	PUNCT
admet-162	232	1	20	20	NUM
admet-162	232	2	(	(	PUNCT
admet-162	232	3	1997	1997	NUM
admet-162	232	4	)	)	PUNCT
admet-162	233	1	438–441	438–441	NUM
admet-162	233	2	.	.	PUNCT
admet-162	234	1	[	[	X
admet-162	234	2	33	33	NUM
admet-162	234	3	]	]	PUNCT
admet-162	234	4	a.	a.	NOUN
admet-162	234	5	lazarowski	lazarowski	PROPN
admet-162	234	6	,	,	PUNCT
admet-162	234	7	m.	m.	NOUN
admet-162	234	8	massaro	massaro	PROPN
admet-162	234	9	,	,	PUNCT
admet-162	234	10	a.	a.	NOUN
admet-162	234	11	schteinschnaider	schteinschnaider	PROPN
admet-162	234	12	,	,	PUNCT
admet-162	234	13	s.	s.	PROPN
admet-162	234	14	intruvini	intruvini	PROPN
admet-162	234	15	,	,	PUNCT
admet-162	234	16	g.	g.	PROPN
admet-162	234	17	sevlever	sevlever	PROPN
admet-162	234	18	,	,	PUNCT
admet-162	234	19	a.	a.	NOUN
admet-162	234	20	rabinowicz	rabinowicz	PROPN
admet-162	234	21	,	,	PUNCT
admet-162	234	22	ther	ther	PROPN
admet-162	234	23	.	.	PUNCT
admet-162	235	1	drug	drug	PROPN
admet-162	235	2	monit	monit	PROPN
admet-162	235	3	.	.	PUNCT
admet-162	236	1	26	26	NUM
admet-162	236	2	(	(	PUNCT
admet-162	236	3	2004	2004	NUM
admet-162	236	4	)	)	PUNCT
admet-162	237	1	44–46	44–46	NUM
admet-162	237	2	.	.	PUNCT
admet-162	238	1	[	[	X
admet-162	238	2	34	34	NUM
admet-162	238	3	]	]	X
admet-162	238	4	c.	c.	PROPN
admet-162	238	5	höcht	höcht	PROPN
admet-162	238	6	,	,	PUNCT
admet-162	238	7	a.	a.	NOUN
admet-162	238	8	lazarowski	lazarowski	PROPN
admet-162	238	9	,	,	PUNCT
admet-162	238	10	n.n	n.n	PROPN
admet-162	238	11	.	.	PROPN
admet-162	238	12	gonzalez	gonzalez	PROPN
admet-162	238	13	,	,	PUNCT
admet-162	238	14	j.	j.	PROPN
admet-162	238	15	auzmendi	auzmendi	PROPN
admet-162	238	16	,	,	PUNCT
admet-162	238	17	j.a	j.a	PROPN
admet-162	238	18	.	.	PROPN
admet-162	238	19	opezzo	opezzo	PROPN
admet-162	238	20	,	,	PUNCT
admet-162	238	21	g.f	g.f	PROPN
admet-162	238	22	.	.	PROPN
admet-162	238	23	bramuglia	bramuglia	PROPN
admet-162	238	24	,	,	PUNCT
admet-162	238	25	c.a	c.a	PROPN
admet-162	238	26	.	.	PROPN
admet-162	238	27	taira	taira	PROPN
admet-162	238	28	,	,	PUNCT
admet-162	238	29	e.	e.	PROPN
admet-162	238	30	girardi	girardi	PROPN
admet-162	238	31	,	,	PUNCT
admet-162	238	32	neurosci	neurosci	PROPN
admet-162	238	33	.	.	PUNCT
admet-162	239	1	lett	lett	PROPN
admet-162	239	2	.	.	PUNCT
admet-162	240	1	413	413	NUM
admet-162	240	2	(	(	PUNCT
admet-162	240	3	2007	2007	NUM
admet-162	240	4	)	)	PUNCT
admet-162	240	5	168	168	NUM
admet-162	240	6	-	-	SYM
admet-162	240	7	72	72	NUM
admet-162	240	8	.	.	PUNCT
admet-162	241	1	[	[	X
admet-162	241	2	35	35	NUM
admet-162	241	3	]	]	X
admet-162	241	4	j.r	j.r	PROPN
admet-162	241	5	.	.	PROPN
admet-162	241	6	hughes	hughes	PROPN
admet-162	241	7	,	,	PUNCT
admet-162	241	8	neurol	neurol	PROPN
admet-162	241	9	.	.	PUNCT
admet-162	242	1	res	re	NOUN
admet-162	242	2	.	.	PROPN
admet-162	243	1	30	30	NUM
admet-162	243	2	(	(	PUNCT
admet-162	243	3	2008	2008	NUM
admet-162	243	4	)	)	PUNCT
admet-162	243	5	920	920	NUM
admet-162	243	6	-	-	SYM
admet-162	243	7	5	5	NUM
admet-162	243	8	.	.	PUNCT
admet-162	244	1	[	[	X
admet-162	244	2	36	36	NUM
admet-162	244	3	]	]	X
admet-162	244	4	e.a	e.a	PROPN
admet-162	244	5	.	.	PROPN
admet-162	244	6	van	van	PROPN
admet-162	244	7	vliet	vliet	PROPN
admet-162	244	8	,	,	PUNCT
admet-162	244	9	r.	r.	PROPN
admet-162	244	10	van	van	PROPN
admet-162	244	11	schaik	schaik	PROPN
admet-162	244	12	,	,	PUNCT
admet-162	244	13	p.m.	p.m.	NOUN
admet-162	244	14	edelbroek	edelbroek	NOUN
admet-162	244	15	,	,	PUNCT
admet-162	244	16	s.	s.	PROPN
admet-162	244	17	redeker	redeker	PROPN
admet-162	244	18	,	,	PUNCT
admet-162	244	19	e.	e.	PROPN
admet-162	244	20	aronica	aronica	PROPN
admet-162	244	21	,	,	PUNCT
admet-162	244	22	w.j	w.j	PROPN
admet-162	244	23	.	.	PROPN
admet-162	244	24	wadman	wadman	PROPN
admet-162	244	25	,	,	PUNCT
admet-162	244	26	n.	n.	PROPN
admet-162	244	27	marchi	marchi	PROPN
admet-162	244	28	,	,	PUNCT
admet-162	244	29	a.	a.	NOUN
admet-162	244	30	vezzani	vezzani	PROPN
admet-162	244	31	,	,	PUNCT
admet-162	244	32	j.a	j.a	PROPN
admet-162	244	33	.	.	PROPN
admet-162	244	34	gorter	gorter	PROPN
admet-162	244	35	,	,	PUNCT
admet-162	244	36	epilepsia	epilepsia	NOUN
admet-162	244	37	47	47	NUM
admet-162	244	38	(	(	PUNCT
admet-162	244	39	2006	2006	NUM
admet-162	244	40	)	)	PUNCT
admet-162	244	41	672	672	NUM
admet-162	244	42	-	-	SYM
admet-162	244	43	80	80	NUM
admet-162	244	44	.	.	PUNCT
admet-162	245	1	[	[	X
admet-162	245	2	37	37	NUM
admet-162	245	3	]	]	PUNCT
admet-162	245	4	t.	t.	PROPN
admet-162	245	5	uematsu	uematsu	PROPN
admet-162	245	6	,	,	PUNCT
admet-162	245	7	m.	m.	PROPN
admet-162	245	8	yamaoka	yamaoka	PROPN
admet-162	245	9	,	,	PUNCT
admet-162	245	10	r.	r.	PROPN
admet-162	245	11	doto	doto	PROPN
admet-162	245	12	,	,	PUNCT
admet-162	245	13	h.	h.	PROPN
admet-162	245	14	tanaka	tanaka	PROPN
admet-162	245	15	,	,	PUNCT
admet-162	245	16	t.	t.	PROPN
admet-162	245	17	matsuura	matsuura	PROPN
admet-162	245	18	,	,	PUNCT
admet-162	245	19	k.	k.	PROPN
admet-162	245	20	furusawa	furusawa	PROPN
admet-162	245	21	,	,	PUNCT
admet-162	245	22	arch	arch	NOUN
admet-162	245	23	.	.	PUNCT
admet-162	246	1	oral	oral	ADJ
admet-162	246	2	biol	biol	NOUN
admet-162	246	3	.	.	PUNCT
admet-162	247	1	48	48	NUM
admet-162	247	2	(	(	PUNCT
admet-162	247	3	2003	2003	NUM
admet-162	247	4	)	)	PUNCT
admet-162	247	5	87	87	NUM
admet-162	247	6	-	-	SYM
admet-162	247	7	90	90	NUM
admet-162	247	8	.	.	PUNCT
admet-162	248	1	[	[	X
admet-162	248	2	38	38	NUM
admet-162	248	3	]	]	PUNCT
admet-162	248	4	p.	p.	PROPN
admet-162	248	5	fagiolino	fagiolino	PROPN
admet-162	248	6	,	,	PUNCT
admet-162	248	7	m.	m.	NOUN
admet-162	248	8	vázquez	vázquez	PROPN
admet-162	248	9	,	,	PUNCT
admet-162	248	10	c.	c.	PROPN
admet-162	248	11	maldonado	maldonado	PROPN
admet-162	248	12	,	,	PUNCT
admet-162	248	13	m.	m.	PROPN
admet-162	248	14	esperanza	esperanza	PROPN
admet-162	248	15	ruiz	ruiz	PROPN
admet-162	248	16	,	,	PUNCT
admet-162	248	17	m.g	m.g	PROPN
admet-162	248	18	.	.	PROPN
admet-162	248	19	volonté	volonté	PROPN
admet-162	248	20	,	,	PUNCT
admet-162	248	21	s.	s.	PROPN
admet-162	248	22	orozco	orozco	PROPN
admet-162	248	23	-	-	PUNCT
admet-162	248	24	suárez	suárez	PROPN
admet-162	248	25	,	,	PUNCT
admet-162	248	26	a.	a.	NOUN
admet-162	248	27	lazarowski	lazarowski	PROPN
admet-162	248	28	,	,	PUNCT
admet-162	249	1	curr	curr	PROPN
admet-162	249	2	.	.	PUNCT
admet-162	249	3	pharm	pharm	PROPN
admet-162	249	4	.	.	PUNCT
admet-162	250	1	des	des	PROPN
admet-162	250	2	.	.	PROPN
admet-162	250	3	19	19	NUM
admet-162	250	4	(	(	PUNCT
admet-162	250	5	2013	2013	NUM
admet-162	250	6	)	)	PUNCT
admet-162	250	7	6767	6767	NUM
admet-162	250	8	-	-	SYM
admet-162	250	9	6774	6774	NUM
admet-162	250	10	.	.	PUNCT
admet-162	251	1	[	[	X
admet-162	251	2	39	39	NUM
admet-162	251	3	]	]	PUNCT
admet-162	251	4	p.	p.	PROPN
admet-162	251	5	iannetti	iannetti	PROPN
admet-162	251	6	,	,	PUNCT
admet-162	251	7	a.	a.	NOUN
admet-162	251	8	spalice	spalice	PROPN
admet-162	251	9	,	,	PUNCT
admet-162	251	10	p.	p.	PROPN
admet-162	251	11	parisi	parisi	PROPN
admet-162	251	12	,	,	PUNCT
admet-162	251	13	epilepsia	epilepsia	NOUN
admet-162	251	14	46	46	NUM
admet-162	251	15	(	(	PUNCT
admet-162	251	16	2005	2005	NUM
admet-162	251	17	)	)	PUNCT
admet-162	251	18	967	967	NUM
admet-162	251	19	-	-	SYM
admet-162	251	20	9	9	NUM
admet-162	251	21	.	.	PUNCT
admet-162	252	1	[	[	X
admet-162	252	2	40	40	NUM
admet-162	252	3	]	]	X
admet-162	252	4	ch	ch	NOUN
admet-162	252	5	.	.	PUNCT
admet-162	252	6	eger	eger	PROPN
admet-162	252	7	,	,	PUNCT
admet-162	252	8	epilepsia	epilepsia	NOUN
admet-162	252	9	44	44	NUM
admet-162	252	10	(	(	PUNCT
admet-162	252	11	2004	2004	NUM
admet-162	252	12	)	)	PUNCT
admet-162	252	13	suppl	suppl	ADJ
admet-162	252	14	.	.	PUNCT
admet-162	253	1	5	5	NUM
admet-162	253	2	:	:	SYM
admet-162	253	3	9	9	NUM
admet-162	253	4	-	-	SYM
admet-162	253	5	15	15	NUM
admet-162	253	6	.	.	PUNCT
admet-162	254	1	[	[	X
admet-162	254	2	41	41	NUM
admet-162	254	3	]	]	X
admet-162	254	4	d.j	d.j	PROPN
admet-162	254	5	.	.	PROPN
admet-162	254	6	roberts	roberts	PROPN
admet-162	254	7	,	,	PUNCT
admet-162	254	8	k.b.goralski	k.b.goralski	ADJ
admet-162	254	9	,	,	PUNCT
admet-162	254	10	expert	expert	NOUN
admet-162	254	11	opin	opin	NOUN
admet-162	254	12	.	.	PUNCT
admet-162	255	1	drug	drug	NOUN
admet-162	255	2	metab	metab	NOUN
admet-162	255	3	.	.	PUNCT
admet-162	256	1	toxicol	toxicol	PROPN
admet-162	256	2	.	.	PUNCT
admet-162	257	1	4	4	NUM
admet-162	257	2	(	(	PUNCT
admet-162	257	3	2008	2008	NUM
admet-162	257	4	)	)	PUNCT
admet-162	257	5	1245	1245	NUM
admet-162	257	6	-	-	SYM
admet-162	257	7	64	64	NUM
admet-162	257	8	.	.	PUNCT
admet-162	258	1	[	[	X
admet-162	258	2	42	42	NUM
admet-162	258	3	]	]	PUNCT
admet-162	258	4	k.	k.	PROPN
admet-162	258	5	kunishio	kunishio	PROPN
admet-162	258	6	,	,	PUNCT
admet-162	258	7	m.	m.	NOUN
admet-162	258	8	okada	okada	PROPN
admet-162	258	9	,	,	PUNCT
admet-162	258	10	y.	y.	PROPN
admet-162	258	11	matsumoto	matsumoto	PROPN
admet-162	258	12	,	,	PUNCT
admet-162	258	13	s.	s.	PROPN
admet-162	258	14	nagao	nagao	PROPN
admet-162	258	15	,	,	PUNCT
admet-162	258	16	y.	y.	PROPN
admet-162	258	17	nishiyama	nishiyama	PROPN
admet-162	258	18	,	,	PUNCT
admet-162	258	19	j.	j.	PROPN
admet-162	258	20	med	med	PROPN
admet-162	258	21	.	.	PUNCT
admet-162	259	1	invest	invest	PROPN
admet-162	259	2	.	.	PUNCT
admet-162	260	1	53	53	NUM
admet-162	260	2	(	(	PUNCT
admet-162	260	3	2006	2006	NUM
admet-162	260	4	)	)	PUNCT
admet-162	260	5	285	285	NUM
admet-162	260	6	-	-	SYM
admet-162	260	7	91	91	NUM
admet-162	260	8	.	.	PUNCT
admet-162	261	1	[	[	X
admet-162	261	2	43	43	NUM
admet-162	261	3	]	]	X
admet-162	261	4	k.m	k.m	PROPN
admet-162	261	5	.	.	PROPN
admet-162	261	6	comerford	comerford	PROPN
admet-162	261	7	,	,	PUNCT
admet-162	261	8	t.j	t.j	PROPN
admet-162	261	9	.	.	PROPN
admet-162	261	10	wallace	wallace	PROPN
admet-162	261	11	,	,	PUNCT
admet-162	261	12	j.	j.	PROPN
admet-162	261	13	karhausen	karhausen	PROPN
admet-162	261	14	,	,	PUNCT
admet-162	261	15	n.a	n.a	PROPN
admet-162	261	16	.	.	PROPN
admet-162	261	17	louis	louis	PROPN
admet-162	261	18	,	,	PUNCT
admet-162	261	19	m.c	m.c	PROPN
admet-162	261	20	.	.	PROPN
admet-162	261	21	montalto	montalto	PROPN
admet-162	261	22	,	,	PUNCT
admet-162	261	23	s.p	s.p	PROPN
admet-162	261	24	.	.	PROPN
admet-162	261	25	colgan	colgan	PROPN
admet-162	261	26	,	,	PUNCT
admet-162	261	27	cancer	cancer	NOUN
admet-162	261	28	res	re	NOUN
admet-162	261	29	.	.	PUNCT
admet-162	262	1	62	62	NUM
admet-162	262	2	(	(	PUNCT
admet-162	262	3	2002	2002	NUM
admet-162	262	4	)	)	PUNCT
admet-162	262	5	3387	3387	NUM
admet-162	262	6	-	-	SYM
admet-162	262	7	94	94	NUM
admet-162	262	8	.	.	PUNCT
admet-162	263	1	[	[	X
admet-162	263	2	44	44	NUM
admet-162	263	3	]	]	PUNCT
admet-162	263	4	a.	a.	NOUN
admet-162	263	5	lazarowski	lazarowski	PROPN
admet-162	263	6	,	,	PUNCT
admet-162	263	7	l.	l.	PROPN
admet-162	263	8	caltana	caltana	PROPN
admet-162	263	9	,	,	PUNCT
admet-162	263	10	a.	a.	NOUN
admet-162	263	11	merelli	merelli	PROPN
admet-162	263	12	,	,	PUNCT
admet-162	263	13	m.	m.	NOUN
admet-162	263	14	rubio	rubio	PROPN
admet-162	263	15	,	,	PUNCT
admet-162	263	16	a.	a.	PROPN
admet-162	263	17	ramos	ramos	PROPN
admet-162	263	18	,	,	PUNCT
admet-162	263	19	a.	a.	PROPN
admet-162	263	20	brusco	brusco	PROPN
admet-162	263	21	,	,	PUNCT
admet-162	263	22	j.	j.	PROPN
admet-162	263	23	neurol	neurol	PROPN
admet-162	263	24	.	.	PUNCT
admet-162	264	1	sci	sci	PROPN
admet-162	264	2	.	.	PROPN
admet-162	264	3	258	258	NUM
admet-162	264	4	(	(	PUNCT
admet-162	264	5	2007	2007	NUM
admet-162	264	6	)	)	PUNCT
admet-162	264	7	84	84	NUM
admet-162	264	8	-	-	SYM
admet-162	264	9	92	92	NUM
admet-162	264	10	.	.	PUNCT
admet-162	265	1	[	[	X
admet-162	265	2	45	45	NUM
admet-162	265	3	]	]	X
admet-162	265	4	e.	e.	PROPN
admet-162	265	5	aronica	aronica	PROPN
admet-162	265	6	,	,	PUNCT
admet-162	265	7	s.m	s.m	PROPN
admet-162	265	8	.	.	PROPN
admet-162	265	9	sisodiya	sisodiya	PROPN
admet-162	265	10	,	,	PUNCT
admet-162	265	11	j.a	j.a	PROPN
admet-162	265	12	.	.	PROPN
admet-162	265	13	gorter	gorter	PROPN
admet-162	265	14	,	,	PUNCT
admet-162	265	15	adv	adv	PROPN
admet-162	265	16	.	.	PUNCT
admet-162	265	17	drug	drug	PROPN
admet-162	265	18	deliv	deliv	PROPN
admet-162	265	19	.	.	PUNCT
admet-162	265	20	rev	rev	PROPN
admet-162	265	21	.	.	PROPN
admet-162	265	22	64	64	NUM
admet-162	265	23	(	(	PUNCT
admet-162	265	24	2012	2012	NUM
admet-162	265	25	)	)	PUNCT
admet-162	265	26	919–29	919–29	NOUN
admet-162	265	27	.	.	PUNCT
admet-162	266	1	[	[	X
admet-162	266	2	46	46	NUM
admet-162	266	3	]	]	X
admet-162	266	4	e.	e.	PROPN
admet-162	266	5	aronica	aronica	PROPN
admet-162	266	6	,	,	PUNCT
admet-162	266	7	j.a	j.a	PROPN
admet-162	266	8	.	.	PROPN
admet-162	266	9	gorter	gorter	PROPN
admet-162	266	10	,	,	PUNCT
admet-162	266	11	g.h	g.h	PROPN
admet-162	266	12	.	.	PROPN
admet-162	266	13	jansen	jansen	PROPN
admet-162	266	14	,	,	PUNCT
admet-162	266	15	c.w	c.w	PROPN
admet-162	266	16	.	.	PROPN
admet-162	266	17	van	van	PROPN
admet-162	266	18	veelen	veelen	PROPN
admet-162	266	19	,	,	PUNCT
admet-162	266	20	p.c	p.c	PROPN
admet-162	266	21	.	.	PROPN
admet-162	266	22	van	van	PROPN
admet-162	266	23	rijen	rijen	PROPN
admet-162	266	24	,	,	PUNCT
admet-162	266	25	s.	s.	PROPN
admet-162	266	26	leenstra	leenstra	PROPN
admet-162	266	27	,	,	PUNCT
admet-162	266	28	m.	m.	NOUN
admet-162	266	29	ramkema	ramkema	NOUN
admet-162	266	30	,	,	PUNCT
admet-162	266	31	g.l	g.l	PROPN
admet-162	266	32	.	.	PROPN
admet-162	266	33	scheffer	scheffer	PROPN
admet-162	266	34	,	,	PUNCT
admet-162	266	35	r.j	r.j	PROPN
admet-162	266	36	.	.	PROPN
admet-162	266	37	scheper	scheper	PROPN
admet-162	266	38	,	,	PUNCT
admet-162	266	39	d.	d.	PROPN
admet-162	266	40	troost	troost	PROPN
admet-162	266	41	,	,	PUNCT
admet-162	266	42	neuroscience	neuroscience	NOUN
admet-162	266	43	118	118	NUM
admet-162	266	44	(	(	PUNCT
admet-162	266	45	2003	2003	NUM
admet-162	266	46	)	)	PUNCT
admet-162	266	47	417–29	417–29	NUM
admet-162	266	48	.	.	PUNCT
admet-162	267	1	[	[	X
admet-162	267	2	47	47	NUM
admet-162	267	3	]	]	X
admet-162	267	4	r.m	r.m	PROPN
admet-162	267	5	.	.	PROPN
admet-162	267	6	wadkins	wadkin	NOUN
admet-162	267	7	,	,	PUNCT
admet-162	267	8	p.d	p.d	PROPN
admet-162	267	9	.	.	PROPN
admet-162	267	10	roepe	roepe	PROPN
admet-162	267	11	.	.	PUNCT
admet-162	268	1	int	int	PROPN
admet-162	268	2	.	.	PUNCT
admet-162	269	1	rev	rev	PROPN
admet-162	269	2	.	.	PROPN
admet-162	270	1	cytol	cytol	PROPN
admet-162	270	2	.	.	PUNCT
admet-162	271	1	171	171	NUM
admet-162	271	2	(	(	PUNCT
admet-162	271	3	1997	1997	NUM
admet-162	271	4	)	)	PUNCT
admet-162	271	5	121–65	121–65	NOUN
admet-162	271	6	.	.	PUNCT
admet-162	272	1	[	[	X
admet-162	272	2	48	48	NUM
admet-162	272	3	]	]	X
admet-162	272	4	p.d	p.d	PROPN
admet-162	272	5	.	.	PROPN
admet-162	272	6	roepe	roepe	PROPN
admet-162	272	7	,	,	PUNCT
admet-162	272	8	curr	curr	PROPN
admet-162	272	9	.	.	PUNCT
admet-162	272	10	pharm	pharm	PROPN
admet-162	272	11	.	.	PUNCT
admet-162	273	1	des	des	PROPN
admet-162	273	2	.	.	PROPN
admet-162	273	3	6	6	NUM
admet-162	273	4	(	(	PUNCT
admet-162	273	5	2000	2000	NUM
admet-162	273	6	)	)	PUNCT
admet-162	273	7	241–60	241–60	NOUN
admet-162	273	8	.	.	PUNCT
admet-162	274	1	[	[	X
admet-162	274	2	49	49	NUM
admet-162	274	3	]	]	X
admet-162	274	4	c.	c.	PROPN
admet-162	274	5	vanoye	vanoye	PROPN
admet-162	274	6	,	,	PUNCT
admet-162	274	7	a.	a.	NOUN
admet-162	274	8	castro	castro	PROPN
admet-162	274	9	,	,	PUNCT
admet-162	274	10	t.	t.	PROPN
admet-162	274	11	pourcher	pourcher	PROPN
admet-162	274	12	,	,	PUNCT
admet-162	274	13	l.	l.	PROPN
admet-162	274	14	reuss	reuss	PROPN
admet-162	274	15	,	,	PUNCT
admet-162	274	16	g.	g.	PROPN
admet-162	274	17	altenberg	altenberg	PROPN
admet-162	274	18	,	,	PUNCT
admet-162	274	19	am	be	AUX
admet-162	274	20	.	.	PUNCT
admet-162	275	1	j.	j.	PROPN
admet-162	275	2	physiol	physiol	PROPN
admet-162	275	3	.	.	PUNCT
admet-162	276	1	276	276	NUM
admet-162	276	2	(	(	PUNCT
admet-162	276	3	1999	1999	NUM
admet-162	276	4	)	)	PUNCT
admet-162	276	5	c370–8	c370–8	NOUN
admet-162	276	6	.	.	PUNCT
admet-162	277	1	[	[	X
admet-162	277	2	50	50	NUM
admet-162	277	3	]	]	PUNCT
admet-162	277	4	m.	m.	NOUN
admet-162	277	5	müller	müller	PROPN
admet-162	277	6	,	,	PUNCT
admet-162	277	7	neuroscience	neuroscience	NOUN
admet-162	277	8	97	97	NUM
admet-162	277	9	(	(	PUNCT
admet-162	277	10	2000	2000	NUM
admet-162	277	11	)	)	PUNCT
admet-162	277	12	33	33	NUM
admet-162	277	13	-	-	SYM
admet-162	277	14	45	45	NUM
admet-162	277	15	.	.	PUNCT
admet-162	278	1	[	[	X
admet-162	278	2	51	51	NUM
admet-162	278	3	]	]	X
admet-162	278	4	c.	c.	PROPN
admet-162	278	5	le	le	PROPN
admet-162	278	6	duigou	duigou	PROPN
admet-162	278	7	,	,	PUNCT
admet-162	278	8	v.	v.	PROPN
admet-162	278	9	bouilleret	bouilleret	PROPN
admet-162	278	10	,	,	PUNCT
admet-162	278	11	r.	r.	PROPN
admet-162	278	12	miles	miles	PROPN
admet-162	278	13	,	,	PUNCT
admet-162	278	14	j.	j.	PROPN
admet-162	278	15	physiol	physiol	PROPN
admet-162	278	16	.	.	PUNCT
admet-162	279	1	586	586	NUM
admet-162	279	2	(	(	PUNCT
admet-162	279	3	2008	2008	NUM
admet-162	279	4	)	)	PUNCT
admet-162	279	5	(	(	PUNCT
admet-162	279	6	pt	pt	INTJ
admet-162	279	7	20	20	NUM
admet-162	279	8	):	):	PUNCT
admet-162	279	9	4891	4891	NUM
admet-162	279	10	-	-	SYM
admet-162	279	11	904	904	NUM
admet-162	279	12	.	.	PUNCT
admet-162	280	1	[	[	X
admet-162	280	2	52	52	NUM
admet-162	280	3	]	]	X
admet-162	280	4	j.a	j.a	PROPN
admet-162	280	5	.	.	PROPN
admet-162	280	6	auzmendi	auzmendi	PROPN
admet-162	280	7	,	,	PUNCT
admet-162	280	8	s.	s.	PROPN
admet-162	280	9	orozco	orozco	PROPN
admet-162	280	10	-	-	PUNCT
admet-162	280	11	suárez	suárez	PROPN
admet-162	280	12	,	,	PUNCT
admet-162	280	13	i.	i.	PROPN
admet-162	280	14	bañuelos	bañuelos	PROPN
admet-162	280	15	-	-	PUNCT
admet-162	280	16	cabrera	cabrera	PROPN
admet-162	280	17	,	,	PUNCT
admet-162	280	18	m.e	m.e	PROPN
admet-162	280	19	.	.	PROPN
admet-162	280	20	gonzález	gonzález	PROPN
admet-162	280	21	-	-	PUNCT
admet-162	280	22	trujano	trujano	PROPN
admet-162	280	23	,	,	PUNCT
admet-162	280	24	e.	e.	PROPN
admet-162	280	25	c.	c.	PROPN
admet-162	280	26	gonzález	gonzález	PROPN
admet-162	280	27	,	,	PUNCT
admet-162	280	28	l.	l.	PROPN
admet-162	280	29	rocha	rocha	PROPN
admet-162	280	30	,	,	PUNCT
admet-162	280	31	a.	a.	NOUN
admet-162	280	32	lazarowski	lazarowski	PROPN
admet-162	280	33	,	,	PUNCT
admet-162	280	34	curr	curr	PROPN
admet-162	280	35	.	.	PUNCT
admet-162	280	36	pharm	pharm	PROPN
admet-162	280	37	.	.	PUNCT
admet-162	281	1	design	design	VERB
admet-162	281	2	19	19	NUM
admet-162	281	3	(	(	PUNCT
admet-162	281	4	2013	2013	NUM
admet-162	281	5	)	)	PUNCT
admet-162	281	6	6732	6732	NUM
admet-162	281	7	-	-	SYM
admet-162	281	8	6738	6738	NUM
admet-162	281	9	.	.	PUNCT
admet-162	282	1	[	[	X
admet-162	282	2	53	53	NUM
admet-162	282	3	]	]	PUNCT
admet-162	282	4	t.	t.	NOUN
admet-162	282	5	mizutani	mizutani	PROPN
admet-162	282	6	,	,	PUNCT
admet-162	282	7	m.	m.	PROPN
admet-162	282	8	masuda	masuda	PROPN
admet-162	282	9	,	,	PUNCT
admet-162	282	10	e.	e.	PROPN
admet-162	282	11	nakai	nakai	PROPN
admet-162	282	12	,	,	PUNCT
admet-162	282	13	k.	k.	PROPN
admet-162	282	14	furumiya	furumiya	PROPN
admet-162	282	15	,	,	PUNCT
admet-162	282	16	h.	h.	PROPN
admet-162	282	17	togawa	togawa	PROPN
admet-162	282	18	,	,	PUNCT
admet-162	282	19	y.	y.	PROPN
admet-162	282	20	nakamura	nakamura	PROPN
admet-162	282	21	,	,	PUNCT
admet-162	282	22	y.	y.	PROPN
admet-162	282	23	kawai	kawai	PROPN
admet-162	282	24	,	,	PUNCT
admet-162	282	25	k.	k.	PROPN
admet-162	282	26	nakahira	nakahira	PROPN
admet-162	282	27	,	,	PUNCT
admet-162	282	28	s.	s.	PROPN
admet-162	282	29	shinkai	shinkai	PROPN
admet-162	282	30	,	,	PUNCT
admet-162	282	31	k.	k.	PROPN
admet-162	282	32	takahashi	takahashi	PROPN
admet-162	282	33	,	,	PUNCT
admet-162	282	34	curr	curr	PROPN
admet-162	282	35	.	.	PROPN
admet-162	282	36	drug	drug	PROPN
admet-162	282	37	metab	metab	NOUN
admet-162	282	38	.	.	PUNCT
admet-162	283	1	9	9	NUM
admet-162	283	2	(	(	PUNCT
admet-162	283	3	2008	2008	NUM
admet-162	283	4	)	)	PUNCT
admet-162	283	5	167	167	NUM
admet-162	283	6	-	-	SYM
admet-162	283	7	74	74	NUM
admet-162	283	8	.	.	PUNCT
admet-162	284	1	[	[	X
admet-162	284	2	54	54	NUM
admet-162	284	3	]	]	X
admet-162	284	4	m.a	m.a	PROPN
admet-162	284	5	.	.	PROPN
admet-162	284	6	valverde	valverde	PROPN
admet-162	284	7	,	,	PUNCT
admet-162	284	8	m.	m.	PROPN
admet-162	284	9	diaz	diaz	PROPN
admet-162	284	10	,	,	PUNCT
admet-162	284	11	f.v	f.v	PROPN
admet-162	284	12	.	.	PROPN
admet-162	284	13	sepulveda	sepulveda	PROPN
admet-162	284	14	,	,	PUNCT
admet-162	284	15	d.r	d.r	PROPN
admet-162	284	16	.	.	PROPN
admet-162	284	17	gill	gill	PROPN
admet-162	284	18	,	,	PUNCT
admet-162	284	19	s.c	s.c	PROPN
admet-162	284	20	.	.	PROPN
admet-162	284	21	hyde	hyde	PROPN
admet-162	284	22	,	,	PUNCT
admet-162	284	23	c.f	c.f	PROPN
admet-162	284	24	.	.	PROPN
admet-162	284	25	higgins	higgins	PROPN
admet-162	284	26	,	,	PUNCT
admet-162	284	27	nature	nature	NOUN
admet-162	284	28	355	355	NUM
admet-162	284	29	(	(	PUNCT
admet-162	284	30	1992	1992	NUM
admet-162	284	31	)	)	PUNCT
admet-162	284	32	830	830	NUM
admet-162	284	33	-	-	SYM
admet-162	284	34	3	3	NUM
admet-162	284	35	.	.	PUNCT
admet-162	285	1	[	[	X
admet-162	285	2	55	55	NUM
admet-162	285	3	]	]	X
admet-162	285	4	b.k	b.k	PROPN
admet-162	285	5	.	.	PROPN
admet-162	285	6	siesjö	siesjö	PROPN
admet-162	285	7	,	,	PUNCT
admet-162	285	8	r.	r.	PROPN
admet-162	285	9	von	von	PROPN
admet-162	285	10	hanwehr	hanwehr	PROPN
admet-162	285	11	,	,	PUNCT
admet-162	285	12	g.	g.	PROPN
admet-162	285	13	nergelius	nergelius	PROPN
admet-162	285	14	,	,	PUNCT
admet-162	285	15	g.	g.	PROPN
admet-162	285	16	nevander	nevander	PROPN
admet-162	285	17	,	,	PUNCT
admet-162	285	18	m.	m.	PROPN
admet-162	285	19	ingvar	ingvar	PROPN
admet-162	285	20	,	,	PUNCT
admet-162	285	21	j.	j.	PROPN
admet-162	285	22	cereb	cereb	PROPN
admet-162	285	23	.	.	PUNCT
admet-162	285	24	blood	blood	NOUN
admet-162	285	25	flow	flow	NOUN
admet-162	285	26	metab	metab	NOUN
admet-162	285	27	.	.	PUNCT
admet-162	286	1	5	5	NUM
admet-162	286	2	(	(	PUNCT
admet-162	286	3	1985	1985	NUM
admet-162	286	4	)	)	PUNCT
admet-162	286	5	47	47	NUM
admet-162	286	6	-	-	SYM
admet-162	286	7	57	57	NUM
admet-162	286	8	.	.	PUNCT
admet-162	287	1	[	[	X
admet-162	287	2	56	56	NUM
admet-162	287	3	]	]	X
admet-162	287	4	d.m	d.m	PROPN
admet-162	287	5	.	.	PROPN
admet-162	287	6	durand	durand	PROPN
admet-162	287	7	,	,	PUNCT
admet-162	287	8	e.h	e.h	PROPN
admet-162	287	9	.	.	PROPN
admet-162	287	10	park	park	PROPN
admet-162	287	11	,	,	PUNCT
admet-162	287	12	a.l	a.l	PROPN
admet-162	287	13	.	.	PROPN
admet-162	287	14	jensen	jensen	PROPN
admet-162	287	15	,	,	PUNCT
admet-162	287	16	philos	philos	PROPN
admet-162	287	17	.	.	PUNCT
admet-162	288	1	trans	trans	PROPN
admet-162	288	2	.	.	PUNCT
admet-162	288	3	r.	r.	PROPN
admet-162	288	4	soc	soc	PROPN
admet-162	288	5	.	.	PUNCT
admet-162	289	1	lond	lond	PROPN
admet-162	289	2	.	.	PUNCT
admet-162	290	1	b	b	X
admet-162	290	2	biol	biol	PROPN
admet-162	290	3	.	.	PUNCT
admet-162	291	1	sci	sci	PROPN
admet-162	291	2	.	.	PROPN
admet-162	292	1	365	365	NUM
admet-162	292	2	(	(	PUNCT
admet-162	292	3	2010):2347	2010):2347	NUM
admet-162	292	4	-	-	SYM
admet-162	292	5	62	62	NUM
admet-162	292	6	.	.	PUNCT
admet-162	293	1	[	[	X
admet-162	293	2	57	57	NUM
admet-162	293	3	]	]	X
admet-162	293	4	d.a	d.a	PROPN
admet-162	293	5	.	.	PROPN
admet-162	293	6	prince	prince	PROPN
admet-162	293	7	,	,	PUNCT
admet-162	293	8	b.w	b.w	PROPN
admet-162	293	9	.	.	PROPN
admet-162	293	10	connors	connors	PROPN
admet-162	293	11	,	,	PUNCT
admet-162	293	12	adv	adv	PROPN
admet-162	293	13	.	.	PUNCT
admet-162	293	14	neurol	neurol	PROPN
admet-162	293	15	.	.	PUNCT
admet-162	294	1	44	44	NUM
admet-162	294	2	(	(	PUNCT
admet-162	294	3	1986	1986	NUM
admet-162	294	4	)	)	PUNCT
admet-162	294	5	275	275	NUM
admet-162	294	6	-	-	SYM
admet-162	294	7	99	99	NUM
admet-162	294	8	.	.	PUNCT
admet-162	295	1	[	[	X
admet-162	295	2	58	58	NUM
admet-162	295	3	]	]	X
admet-162	295	4	a.j	a.j	PROPN
admet-162	295	5	.	.	PROPN
admet-162	295	6	ramos	ramos	PROPN
admet-162	295	7	,	,	PUNCT
admet-162	295	8	a.	a.	NOUN
admet-162	295	9	lazarowski	lazarowski	PROPN
admet-162	295	10	,	,	PUNCT
admet-162	295	11	m.	m.	NOUN
admet-162	295	12	villar	villar	PROPN
admet-162	295	13	,	,	PUNCT
admet-162	295	14	a.	a.	PROPN
admet-162	295	15	brusco	brusco	PROPN
admet-162	295	16	,	,	PUNCT
admet-162	295	17	cell	cell	NOUN
admet-162	295	18	.	.	PUNCT
admet-162	296	1	mol	mol	X
admet-162	296	2	.	.	PUNCT
admet-162	297	1	neurobiol.24	neurobiol.24	NOUN
admet-162	297	2	(	(	PUNCT
admet-162	297	3	2004	2004	NUM
admet-162	297	4	)	)	PUNCT
admet-162	297	5	101	101	NUM
admet-162	297	6	-	-	SYM
admet-162	297	7	7	7	NUM
admet-162	297	8	.	.	PUNCT
admet-162	298	1	[	[	X
admet-162	298	2	59	59	NUM
admet-162	298	3	]	]	X
admet-162	298	4	l.	l.	PROPN
admet-162	298	5	nashef	nashef	PROPN
admet-162	298	6	,	,	PUNCT
admet-162	298	7	epilepsia	epilepsia	NOUN
admet-162	298	8	38	38	NUM
admet-162	298	9	(	(	PUNCT
admet-162	298	10	1997	1997	NUM
admet-162	298	11	)	)	PUNCT
admet-162	298	12	6	6	NUM
admet-162	298	13	-	-	SYM
admet-162	298	14	8	8	NUM
admet-162	298	15	.	.	PUNCT
admet-162	299	1	[	[	X
admet-162	299	2	60	60	NUM
admet-162	299	3	]	]	PUNCT
admet-162	299	4	s.	s.	PROPN
admet-162	299	5	kirby	kirby	PROPN
admet-162	299	6	,	,	PUNCT
admet-162	299	7	r.m	r.m	PROPN
admet-162	299	8	,	,	PUNCT
admet-162	299	9	epilepsia	epilepsia	NOUN
admet-162	299	10	36	36	NUM
admet-162	299	11	(	(	PUNCT
admet-162	299	12	1995	1995	NUM
admet-162	299	13	)	)	PUNCT
admet-162	299	14	25	25	NUM
admet-162	299	15	-	-	SYM
admet-162	299	16	28	28	NUM
admet-162	299	17	.	.	PUNCT
admet-162	300	1	[	[	X
admet-162	300	2	61	61	NUM
admet-162	300	3	]	]	PUNCT
admet-162	300	4	l.	l.	PROPN
admet-162	300	5	nashef	nashef	PROPN
admet-162	300	6	,	,	PUNCT
admet-162	300	7	f.	f.	PROPN
admet-162	300	8	walker	walker	PROPN
admet-162	300	9	,	,	PUNCT
admet-162	300	10	p.	p.	PROPN
admet-162	300	11	allen	allen	PROPN
admet-162	300	12	,	,	PUNCT
admet-162	300	13	j.w	j.w	PROPN
admet-162	300	14	.	.	PROPN
admet-162	300	15	sander	sander	PROPN
admet-162	300	16	,	,	PUNCT
admet-162	300	17	s.	s.	PROPN
admet-162	300	18	shorvon	shorvon	PROPN
admet-162	300	19	,	,	PUNCT
admet-162	300	20	d.	d.	PROPN
admet-162	300	21	fish	fish	PROPN
admet-162	300	22	,	,	PUNCT
admet-162	300	23	j.	j.	PROPN
admet-162	300	24	neurol	neurol	PROPN
admet-162	300	25	.	.	PUNCT
admet-162	301	1	neurosurg	neurosurg	PROPN
admet-162	301	2	.	.	PUNCT
admet-162	302	1	psychiatry	psychiatry	NOUN
admet-162	302	2	60	60	NUM
admet-162	302	3	(	(	PUNCT
admet-162	302	4	1996)297–300	1996)297–300	NUM
admet-162	302	5	.	.	PUNCT
admet-162	303	1	[	[	X
admet-162	303	2	62	62	NUM
admet-162	303	3	]	]	PUNCT
admet-162	303	4	s.	s.	PROPN
admet-162	303	5	tigaran	tigaran	PROPN
admet-162	303	6	,	,	PUNCT
admet-162	303	7	h.	h.	PROPN
admet-162	303	8	molgaard	molgaard	PROPN
admet-162	303	9	,	,	PUNCT
admet-162	303	10	r.	r.	PROPN
admet-162	303	11	mcclelland	mcclelland	PROPN
admet-162	303	12	,	,	PUNCT
admet-162	303	13	m.	m.	NOUN
admet-162	303	14	dam	dam	PROPN
admet-162	303	15	,	,	PUNCT
admet-162	303	16	a.s	a.s	PROPN
admet-162	303	17	.	.	PROPN
admet-162	303	18	jaffe	jaffe	PROPN
admet-162	303	19	,	,	PUNCT
admet-162	303	20	neurology	neurology	NOUN
admet-162	303	21	60	60	NUM
admet-162	303	22	(	(	PUNCT
admet-162	303	23	2003	2003	NUM
admet-162	303	24	)	)	PUNCT
admet-162	304	1	492–495	492–495	NUM
admet-162	304	2	.	.	PUNCT
admet-162	305	1	admet	admet	PROPN
admet-162	305	2	&	&	CCONJ
admet-162	305	3	dmpk	dmpk	PROPN
admet-162	305	4	3(2	3(2	NUM
admet-162	305	5	)	)	PUNCT
admet-162	305	6	(	(	PUNCT
admet-162	305	7	2015	2015	NUM
admet-162	305	8	)	)	PUNCT
admet-162	305	9	110	110	NUM
admet-162	305	10	-	-	SYM
admet-162	305	11	121	121	NUM
admet-162	305	12	the	the	DET
admet-162	305	13	roles	role	NOUN
admet-162	305	14	of	of	ADP
admet-162	305	15	p	p	NOUN
admet-162	305	16	-	-	PUNCT
admet-162	305	17	gp	gp	NOUN
admet-162	305	18	in	in	ADP
admet-162	305	19	refractory	refractory	NOUN
admet-162	305	20	epilepsy	epilepsy	NOUN
admet-162	305	21	doi	doi	NOUN
admet-162	305	22	:	:	PUNCT
admet-162	305	23	10.5599	10.5599	NUM
admet-162	305	24	/	/	SYM
admet-162	305	25	admet.3.2.162	admet.3.2.162	ADP
admet-162	305	26	121	121	NUM
admet-162	305	27	[	[	SYM
admet-162	305	28	63	63	NUM
admet-162	305	29	]	]	SYM
admet-162	305	30	s.u	s.u	PROPN
admet-162	305	31	.	.	PROPN
admet-162	305	32	schuele	schuele	PROPN
admet-162	305	33	,	,	PUNCT
admet-162	305	34	p.	p.	NOUN
admet-162	305	35	widdess	widdess	NOUN
admet-162	305	36	-	-	PUNCT
admet-162	305	37	walsh	walsh	NOUN
admet-162	305	38	,	,	PUNCT
admet-162	305	39	a.	a.	NOUN
admet-162	305	40	bermeo	bermeo	NOUN
admet-162	305	41	,	,	PUNCT
admet-162	305	42	h.	h.	PROPN
admet-162	305	43	lüders	lüders	PROPN
admet-162	305	44	,	,	PUNCT
admet-162	305	45	cleve	cleve	PROPN
admet-162	305	46	.	.	PUNCT
admet-162	306	1	clin	clin	PROPN
admet-162	306	2	.	.	PUNCT
admet-162	307	1	j.	j.	PROPN
admet-162	307	2	med	med	PROPN
admet-162	307	3	.	.	PUNCT
admet-162	308	1	74	74	NUM
admet-162	308	2	(	(	PUNCT
admet-162	308	3	2007	2007	NUM
admet-162	308	4	)	)	PUNCT
admet-162	309	1	suppl	suppl	ADJ
admet-162	309	2	1	1	NUM
admet-162	309	3	:	:	PUNCT
admet-162	309	4	s121127	s121127	PROPN
admet-162	309	5	.	.	PUNCT
admet-162	310	1	[	[	X
admet-162	310	2	64	64	NUM
admet-162	310	3	]	]	X
admet-162	310	4	a.j	a.j	PROPN
admet-162	310	5	.	.	PROPN
admet-162	310	6	lazarowski	lazarowski	PROPN
admet-162	310	7	,	,	PUNCT
admet-162	310	8	h.j	h.j	PROPN
admet-162	310	9	.	.	PROPN
admet-162	310	10	garcía	garcía	PROPN
admet-162	310	11	rivello	rivello	PROPN
admet-162	310	12	,	,	PUNCT
admet-162	310	13	g.l	g.l	PROPN
admet-162	310	14	.	.	PROPN
admet-162	310	15	vera	vera	PROPN
admet-162	310	16	janavel	janavel	PROPN
admet-162	310	17	,	,	PUNCT
admet-162	310	18	l.a	l.a	PROPN
admet-162	310	19	.	.	PROPN
admet-162	310	20	cuniberti	cuniberti	PROPN
admet-162	310	21	,	,	PUNCT
admet-162	310	22	p.m.	p.m.	PROPN
admet-162	310	23	cabeza	cabeza	PROPN
admet-162	310	24	meckert	meckert	PROPN
admet-162	310	25	,	,	PUNCT
admet-162	310	26	g.g	g.g	PROPN
admet-162	310	27	.	.	PROPN
admet-162	310	28	yannarelli	yannarelli	PROPN
admet-162	310	29	,	,	PUNCT
admet-162	310	30	a.	a.	PROPN
admet-162	310	31	mele	mele	PROPN
admet-162	310	32	,	,	PUNCT
admet-162	310	33	a.j	a.j	PROPN
admet-162	310	34	.	.	PROPN
admet-162	310	35	crottogini	crottogini	PROPN
admet-162	310	36	,	,	PUNCT
admet-162	310	37	r.p	r.p	PROPN
admet-162	310	38	.	.	PROPN
admet-162	310	39	laguens	laguens	PROPN
admet-162	310	40	.	.	PUNCT
admet-162	311	1	j.	j.	PROPN
admet-162	311	2	histochem	histochem	PROPN
admet-162	311	3	.	.	PUNCT
admet-162	312	1	cytochem	cytochem	PROPN
admet-162	312	2	.	.	PUNCT
admet-162	313	1	53	53	NUM
admet-162	313	2	(	(	PUNCT
admet-162	313	3	2005	2005	NUM
admet-162	313	4	)	)	PUNCT
admet-162	313	5	845–850	845–850	NUM
admet-162	313	6	.	.	PUNCT
admet-162	314	1	[	[	X
admet-162	314	2	65	65	NUM
admet-162	314	3	]	]	X
admet-162	314	4	r.p	r.p	PROPN
admet-162	314	5	.	.	PROPN
admet-162	314	6	laguens	laguens	PROPN
admet-162	314	7	,	,	PUNCT
admet-162	314	8	a.j	a.j	PROPN
admet-162	314	9	.	.	PROPN
admet-162	314	10	lazarowski	lazarowski	PROPN
admet-162	314	11	,	,	PUNCT
admet-162	314	12	l.a	l.a	PROPN
admet-162	314	13	.	.	PROPN
admet-162	314	14	cuniberti	cuniberti	PROPN
admet-162	314	15	,	,	PUNCT
admet-162	314	16	g.l	g.l	PROPN
admet-162	314	17	.	.	PROPN
admet-162	314	18	vera	vera	NOUN
admet-162	314	19	-	-	PUNCT
admet-162	314	20	janavel	janavel	NOUN
admet-162	314	21	,	,	PUNCT
admet-162	314	22	p.m.	p.m.	NOUN
admet-162	314	23	cabeza	cabeza	PROPN
admet-162	314	24	meckert	meckert	PROPN
admet-162	314	25	,	,	PUNCT
admet-162	314	26	g.g	g.g	PROPN
admet-162	314	27	.	.	PROPN
admet-162	314	28	yannarelli	yannarelli	PROPN
admet-162	314	29	,	,	PUNCT
admet-162	314	30	h.f	h.f	PROPN
admet-162	314	31	.	.	PROPN
admet-162	314	32	del	del	PROPN
admet-162	314	33	valle	valle	PROPN
admet-162	314	34	,	,	PUNCT
admet-162	314	35	e.c	e.c	PROPN
admet-162	314	36	.	.	PROPN
admet-162	314	37	lascano	lascano	PROPN
admet-162	314	38	,	,	PUNCT
admet-162	314	39	j.a	j.a	PROPN
admet-162	314	40	.	.	PROPN
admet-162	314	41	negroni	negroni	PROPN
admet-162	314	42	,	,	PUNCT
admet-162	314	43	a.j	a.j	PROPN
admet-162	314	44	.	.	PROPN
admet-162	314	45	crottogini	crottogini	PROPN
admet-162	314	46	,	,	PUNCT
admet-162	314	47	j.	j.	PROPN
admet-162	314	48	histochem	histochem	PROPN
admet-162	314	49	.	.	PUNCT
admet-162	314	50	cytochem	cytochem	PROPN
admet-162	314	51	.	.	PUNCT
admet-162	315	1	55	55	NUM
admet-162	315	2	(	(	PUNCT
admet-162	315	3	2007	2007	NUM
admet-162	315	4	)	)	PUNCT
admet-162	315	5	191–197	191–197	NUM
admet-162	315	6	.	.	PUNCT
admet-162	316	1	[	[	X
admet-162	316	2	66	66	NUM
admet-162	316	3	]	]	PUNCT
admet-162	316	4	j.auzmendi	j.auzmendi	NOUN
admet-162	316	5	,	,	PUNCT
admet-162	316	6	a.	a.	NOUN
admet-162	316	7	merelli	merelli	PROPN
admet-162	316	8	,	,	PUNCT
admet-162	316	9	e.	e.	PROPN
admet-162	316	10	girardi	girardi	PROPN
admet-162	316	11	,	,	PUNCT
admet-162	316	12	s.	s.	PROPN
admet-162	316	13	orozco	orozco	PROPN
admet-162	316	14	-	-	PUNCT
admet-162	316	15	suarez	suarez	PROPN
admet-162	316	16	,	,	PUNCT
admet-162	316	17	l.	l.	PROPN
admet-162	316	18	rocha	rocha	PROPN
admet-162	316	19	,	,	PUNCT
admet-162	316	20	a.	a.	NOUN
admet-162	316	21	lazarowski	lazarowski	PROPN
admet-162	316	22	,	,	PUNCT
admet-162	316	23	mol	mol	PROPN
admet-162	316	24	.	.	PROPN
admet-162	316	25	cell	cell	NOUN
admet-162	316	26	.	.	PUNCT
admet-162	317	1	epilepsy	epilepsy	NOUN
admet-162	317	2	1	1	NUM
admet-162	317	3	(	(	PUNCT
admet-162	317	4	2014	2014	NUM
admet-162	317	5	)	)	PUNCT
admet-162	317	6	e66	e66	NOUN
admet-162	317	7	.	.	PUNCT
admet-162	318	1	doi	doi	NOUN
admet-162	318	2	:	:	PUNCT
admet-162	318	3	10.14800	10.14800	NUM
admet-162	318	4	/	/	SYM
admet-162	318	5	mce.66	mce.66	NOUN
admet-162	318	6	.	.	PUNCT
admet-162	319	1	[	[	X
admet-162	319	2	67	67	NUM
admet-162	319	3	]	]	X
admet-162	319	4	e.	e.	PROPN
admet-162	319	5	brodtkorb	brodtkorb	PROPN
admet-162	319	6	,	,	PUNCT
admet-162	319	7	g.	g.	PROPN
admet-162	319	8	nilsen	nilsen	PROPN
admet-162	319	9	,	,	PUNCT
admet-162	319	10	o.	o.	PROPN
admet-162	319	11	smevik	smevik	PROPN
admet-162	319	12	,	,	PUNCT
admet-162	319	13	p.a	p.a	PROPN
admet-162	319	14	.	.	PROPN
admet-162	319	15	rinck	rinck	NOUN
admet-162	319	16	,	,	PUNCT
admet-162	319	17	acta	acta	PROPN
admet-162	319	18	neurol	neurol	PROPN
admet-162	319	19	.	.	PUNCT
admet-162	320	1	scand	scand	PROPN
admet-162	320	2	.	.	PUNCT
admet-162	321	1	86	86	NUM
admet-162	321	2	(	(	PUNCT
admet-162	321	3	1992	1992	NUM
admet-162	321	4	)	)	PUNCT
admet-162	321	5	24–32	24–32	NUM
admet-162	321	6	.	.	PUNCT
admet-162	322	1	[	[	X
admet-162	322	2	68	68	NUM
admet-162	322	3	]	]	X
admet-162	322	4	s.m	s.m	PROPN
admet-162	322	5	.	.	PROPN
admet-162	322	6	sisodiya	sisodiya	PROPN
admet-162	322	7	,	,	PUNCT
admet-162	322	8	j.	j.	PROPN
admet-162	322	9	heffernan	heffernan	PROPN
admet-162	322	10	,	,	PUNCT
admet-162	322	11	m.v	m.v	PROPN
admet-162	322	12	.	.	PROPN
admet-162	322	13	squier	squier	PROPN
admet-162	322	14	,	,	PUNCT
admet-162	322	15	neuroreport	neuroreport	NOUN
admet-162	322	16	10	10	NUM
admet-162	322	17	(	(	PUNCT
admet-162	322	18	(	(	PUNCT
admet-162	322	19	1999	1999	NUM
admet-162	322	20	)	)	PUNCT
admet-162	322	21	3437	3437	NUM
admet-162	322	22	-	-	SYM
admet-162	322	23	41	41	NUM
admet-162	322	24	.	.	PUNCT
admet-162	323	1	[	[	X
admet-162	323	2	69	69	NUM
admet-162	323	3	]	]	PUNCT
admet-162	323	4	a.	a.	NOUN
admet-162	323	5	lazarowski	lazarowski	PROPN
admet-162	323	6	,	,	PUNCT
admet-162	323	7	f.	f.	PROPN
admet-162	323	8	lubieniecki	lubieniecki	PROPN
admet-162	323	9	,	,	PUNCT
admet-162	323	10	s.	s.	PROPN
admet-162	323	11	camarero	camarero	PROPN
admet-162	323	12	,	,	PUNCT
admet-162	323	13	v.	v.	CCONJ
admet-162	323	14	cuccia	cuccia	PROPN
admet-162	323	15	,	,	PUNCT
admet-162	323	16	a.l.taratuto	a.l.taratuto	PROPN
admet-162	323	17	.	.	PUNCT
admet-162	324	1	receptor	receptor	PROPN
admet-162	324	2	clin	clin	PROPN
admet-162	324	3	.	.	PUNCT
admet-162	325	1	invest	invest	VERB
admet-162	325	2	.	.	PUNCT
admet-162	326	1	1	1	NUM
admet-162	326	2	(	(	PUNCT
admet-162	326	3	2014	2014	NUM
admet-162	326	4	)	)	PUNCT
admet-162	326	5	e53	e53	PROPN
admet-162	326	6	.	.	PUNCT
admet-162	327	1	doi	doi	NOUN
admet-162	327	2	:	:	PUNCT
admet-162	327	3	10.14800	10.14800	NUM
admet-162	327	4	/	/	SYM
admet-162	327	5	rci.53	rci.53	NOUN
admet-162	327	6	[	[	PUNCT
admet-162	327	7	70	70	NUM
admet-162	327	8	]	]	PUNCT
admet-162	327	9	j.	j.	PROPN
admet-162	327	10	fassunke	fassunke	PROPN
admet-162	327	11	,	,	PUNCT
admet-162	327	12	m.	m.	NOUN
admet-162	327	13	majores	majore	NOUN
admet-162	327	14	,	,	PUNCT
admet-162	327	15	c.	c.	PROPN
admet-162	327	16	ullmann	ullmann	PROPN
admet-162	327	17	,	,	PUNCT
admet-162	327	18	ch.e	ch.e	PROPN
admet-162	327	19	.	.	PUNCT
admet-162	328	1	elger	elger	PROPN
admet-162	328	2	,	,	PUNCT
admet-162	328	3	j.	j.	PROPN
admet-162	328	4	schramm	schramm	PROPN
admet-162	328	5	,	,	PUNCT
admet-162	328	6	o.d	o.d	PROPN
admet-162	328	7	.	.	PROPN
admet-162	328	8	wiestler	wiestler	PROPN
admet-162	328	9	,	,	PUNCT
admet-162	328	10	a.j	a.j	PROPN
admet-162	328	11	.	.	PROPN
admet-162	328	12	becker	becker	PROPN
admet-162	328	13	,	,	PUNCT
admet-162	328	14	lab	lab	PROPN
admet-162	328	15	.	.	PUNCT
admet-162	328	16	invest	invest	PROPN
admet-162	328	17	.	.	PUNCT
admet-162	329	1	84	84	NUM
admet-162	329	2	(	(	PUNCT
admet-162	329	3	2004)1520–1525	2004)1520–1525	NUM
admet-162	329	4	.	.	PUNCT
admet-162	330	1	[	[	X
admet-162	330	2	71	71	NUM
admet-162	330	3	]	]	X
admet-162	330	4	c.	c.	PROPN
admet-162	330	5	reali	reali	PROPN
admet-162	330	6	,	,	PUNCT
admet-162	330	7	f.	f.	PROPN
admet-162	330	8	scintu	scintu	PROPN
admet-162	330	9	,	,	PUNCT
admet-162	330	10	r.	r.	PROPN
admet-162	330	11	pillai	pillai	PROPN
admet-162	330	12	,	,	PUNCT
admet-162	330	13	s.	s.	PROPN
admet-162	330	14	cabras	cabras	PROPN
admet-162	330	15	,	,	PUNCT
admet-162	330	16	f.	f.	PROPN
admet-162	330	17	argiolu	argiolu	PROPN
admet-162	330	18	,	,	PUNCT
admet-162	330	19	m.s	m.s	PROPN
admet-162	330	20	.	.	PROPN
admet-162	330	21	ristaldi	ristaldi	PROPN
admet-162	330	22	,	,	PUNCT
admet-162	330	23	m.a	m.a	PROPN
admet-162	330	24	.	.	PROPN
admet-162	330	25	sanna	sanna	PROPN
admet-162	330	26	,	,	PUNCT
admet-162	330	27	m.	m.	NOUN
admet-162	330	28	badiali	badiali	PROPN
admet-162	330	29	,	,	PUNCT
admet-162	330	30	v.	v.	ADP
admet-162	330	31	sogos	sogo	NOUN
admet-162	330	32	.	.	PUNCT
admet-162	331	1	exp	exp	NOUN
admet-162	331	2	.	.	PUNCT
admet-162	332	1	neurol	neurol	PROPN
admet-162	332	2	.	.	PUNCT
admet-162	333	1	197(2006	197(2006	NUM
admet-162	333	2	)	)	PUNCT
admet-162	333	3	399	399	NUM
admet-162	333	4	-	-	SYM
admet-162	333	5	406	406	NUM
admet-162	333	6	.	.	PUNCT
admet-162	334	1	[	[	X
admet-162	334	2	72	72	NUM
admet-162	334	3	]	]	X
admet-162	334	4	s.	s.	PROPN
admet-162	334	5	fauser	fauser	PROPN
admet-162	334	6	,	,	PUNCT
admet-162	334	7	a.	a.	NOUN
admet-162	334	8	becker	becker	PROPN
admet-162	334	9	,	,	PUNCT
admet-162	334	10	a.	a.	PROPN
admet-162	334	11	schulze	schulze	NOUN
admet-162	334	12	-	-	PUNCT
admet-162	334	13	bonhage	bonhage	NOUN
admet-162	334	14	,	,	PUNCT
admet-162	334	15	m.	m.	NOUN
admet-162	334	16	hildebrandt	hildebrandt	PROPN
admet-162	334	17	,	,	PUNCT
admet-162	334	18	i.	i.	PROPN
admet-162	334	19	tuxhorn	tuxhorn	PROPN
admet-162	334	20	,	,	PUNCT
admet-162	334	21	h.w	h.w	PROPN
admet-162	334	22	.	.	PUNCT
admet-162	334	23	pannek	pannek	PROPN
admet-162	334	24	,	,	PUNCT
admet-162	334	25	r.	r.	PROPN
admet-162	334	26	lahl	lahl	PROPN
admet-162	334	27	,	,	PUNCT
admet-162	334	28	j.	j.	PROPN
admet-162	334	29	schramm	schramm	PROPN
admet-162	334	30	,	,	PUNCT
admet-162	334	31	i.	i.	PROPN
admet-162	334	32	blumcke	blumcke	PROPN
admet-162	334	33	,	,	PUNCT
admet-162	334	34	acta	acta	PROPN
admet-162	334	35	neuropathol	neuropathol	PROPN
admet-162	334	36	.	.	PUNCT
admet-162	335	1	108	108	NUM
admet-162	335	2	(	(	PUNCT
admet-162	335	3	2004	2004	NUM
admet-162	335	4	)	)	PUNCT
admet-162	335	5	272	272	NUM
admet-162	335	6	-	-	SYM
admet-162	335	7	8	8	NUM
admet-162	335	8	.	.	PUNCT
admet-162	336	1	[	[	X
admet-162	336	2	73	73	NUM
admet-162	336	3	]	]	X
admet-162	336	4	m.s	m.s	PROPN
admet-162	336	5	.	.	PROPN
admet-162	336	6	van	van	PROPN
admet-162	336	7	breemen	breemen	PROPN
admet-162	336	8	,	,	PUNCT
admet-162	336	9	e.b	e.b	PROPN
admet-162	336	10	.	.	PROPN
admet-162	336	11	wilms	wilms	PROPN
admet-162	336	12	,	,	PUNCT
admet-162	336	13	c.j	c.j	PROPN
admet-162	336	14	.	.	PROPN
admet-162	336	15	vecht	vecht	PROPN
admet-162	336	16	.	.	PUNCT
admet-162	337	1	lancet	lancet	PROPN
admet-162	337	2	neurol	neurol	PROPN
admet-162	337	3	.	.	PUNCT
admet-162	338	1	6	6	NUM
admet-162	338	2	(	(	PUNCT
admet-162	338	3	2007	2007	NUM
admet-162	338	4	)	)	PUNCT
admet-162	338	5	421	421	NUM
admet-162	338	6	-	-	SYM
admet-162	338	7	30	30	NUM
admet-162	338	8	.	.	PUNCT
admet-162	339	1	[	[	X
admet-162	339	2	74	74	X
admet-162	339	3	]	]	PUNCT
admet-162	339	4	t.	t.	PROPN
admet-162	339	5	lin	lin	PROPN
admet-162	339	6	,	,	PUNCT
admet-162	339	7	o.	o.	PROPN
admet-162	339	8	islam	islam	PROPN
admet-162	339	9	,	,	PUNCT
admet-162	339	10	k.	k.	PROPN
admet-162	339	11	heese	heese	PROPN
admet-162	339	12	,	,	PUNCT
admet-162	339	13	cell	cell	NOUN
admet-162	339	14	res	re	NOUN
admet-162	339	15	.	.	PUNCT
admet-162	340	1	16	16	NUM
admet-162	340	2	(	(	PUNCT
admet-162	340	3	2006	2006	NUM
admet-162	340	4	)	)	PUNCT
admet-162	340	5	857	857	NUM
admet-162	340	6	-	-	SYM
admet-162	340	7	871	871	NUM
admet-162	340	8	.	.	PUNCT
admet-162	341	1	[	[	X
admet-162	341	2	75	75	NUM
admet-162	341	3	]	]	PUNCT
admet-162	341	4	t.	t.	PROPN
admet-162	341	5	schumacher	schumacher	PROPN
admet-162	341	6	,	,	PUNCT
admet-162	341	7	m.	m.	PROPN
admet-162	341	8	krohn	krohn	PROPN
admet-162	341	9	,	,	PUNCT
admet-162	341	10	j.	j.	PROPN
admet-162	341	11	hofrichter	hofrichter	PROPN
admet-162	341	12	,	,	PUNCT
admet-162	341	13	c.	c.	PROPN
admet-162	341	14	lange	lange	PROPN
admet-162	341	15	,	,	PUNCT
admet-162	341	16	j.	j.	PROPN
admet-162	341	17	stenzel	stenzel	PROPN
admet-162	341	18	,	,	PUNCT
admet-162	341	19	j.	j.	PROPN
admet-162	341	20	steffen	steffen	PROPN
admet-162	341	21	,	,	PUNCT
admet-162	341	22	t.	t.	PROPN
admet-162	341	23	dunkelmann	dunkelmann	PROPN
admet-162	341	24	,	,	PUNCT
admet-162	341	25	k.	k.	PROPN
admet-162	341	26	paarmann	paarmann	PROPN
admet-162	341	27	,	,	PUNCT
admet-162	341	28	c.	c.	PROPN
admet-162	341	29	fröhlich	fröhlich	PROPN
admet-162	341	30	,	,	PUNCT
admet-162	341	31	a.	a.	NOUN
admet-162	341	32	uecker	uecker	NOUN
admet-162	341	33	,	,	PUNCT
admet-162	341	34	a.s	a.s	PROPN
admet-162	341	35	.	.	PROPN
admet-162	341	36	plath	plath	PROPN
admet-162	341	37	,	,	PUNCT
admet-162	341	38	a.	a.	NOUN
admet-162	341	39	sommer	sommer	NOUN
admet-162	341	40	,	,	PUNCT
admet-162	341	41	t.	t.	PROPN
admet-162	341	42	brüning	brüning	PROPN
admet-162	341	43	,	,	PUNCT
admet-162	341	44	h.j	h.j	PROPN
admet-162	341	45	.	.	PROPN
admet-162	341	46	heinze	heinze	PROPN
admet-162	341	47	,	,	PUNCT
admet-162	341	48	j.	j.	PROPN
admet-162	341	49	pahnke	pahnke	PROPN
admet-162	341	50	.	.	PUNCT
admet-162	342	1	plos	plos	PROPN
admet-162	342	2	one	one	NUM
admet-162	342	3	7	7	NUM
admet-162	342	4	(	(	PUNCT
admet-162	342	5	2012	2012	NUM
admet-162	342	6	)	)	PUNCT
admet-162	343	1	e35613	e35613	PROPN
admet-162	343	2	[	[	X
admet-162	343	3	76	76	NUM
admet-162	343	4	]	]	X
admet-162	343	5	l.	l.	PROPN
admet-162	343	6	czornyj	czornyj	PROPN
admet-162	343	7	,	,	PUNCT
admet-162	343	8	a.	a.	NOUN
admet-162	343	9	lazarowski	lazarowski	PROPN
admet-162	343	10	.	.	PUNCT
admet-162	344	1	front	front	NOUN
admet-162	344	2	.	.	PUNCT
admet-162	345	1	biosci	biosci	PROPN
admet-162	345	2	.	.	PUNCT
admet-162	346	1	19	19	NUM
admet-162	346	2	(	(	PUNCT
admet-162	346	3	2014	2014	NUM
admet-162	346	4	)	)	PUNCT
admet-162	346	5	1425	1425	NUM
admet-162	346	6	-	-	SYM
admet-162	346	7	1435	1435	NUM
admet-162	346	8	.	.	PUNCT
admet-162	347	1	©	©	PROPN
admet-162	347	2	2015	2015	NUM
admet-162	347	3	by	by	ADP
admet-162	347	4	the	the	DET
admet-162	347	5	authors	author	NOUN
admet-162	347	6	;	;	PUNCT
admet-162	347	7	licensee	licensee	PROPN
admet-162	347	8	iapc	iapc	PROPN
admet-162	347	9	,	,	PUNCT
admet-162	347	10	zagreb	zagreb	PROPN
admet-162	347	11	,	,	PUNCT
admet-162	347	12	croatia	croatia	PROPN
admet-162	347	13	.	.	PUNCT
admet-162	348	1	this	this	DET
admet-162	348	2	article	article	NOUN
admet-162	348	3	is	be	AUX
admet-162	348	4	an	an	DET
admet-162	348	5	open	open	ADJ
admet-162	348	6	-	-	PUNCT
admet-162	348	7	access	access	NOUN
admet-162	348	8	article	article	NOUN
admet-162	348	9	distributed	distribute	VERB
admet-162	348	10	under	under	ADP
admet-162	348	11	the	the	DET
admet-162	348	12	terms	term	NOUN
admet-162	348	13	and	and	CCONJ
admet-162	348	14	conditions	condition	NOUN
admet-162	348	15	of	of	ADP
admet-162	348	16	the	the	DET
admet-162	348	17	creative	creative	ADJ
admet-162	348	18	commons	common	NOUN
admet-162	348	19	attribution	attribution	NOUN
admet-162	348	20	license	license	NOUN
admet-162	348	21	(	(	PUNCT
admet-162	348	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-162	348	23	)	)	PUNCT
admet-162	348	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN