id	sid	tid	token	lemma	pos
admet-1885	1	1	anti	anti	ADJ
admet-1885	1	2	-	-	ADJ
admet-1885	1	3	inflammatory	inflammatory	ADJ
admet-1885	1	4	activities	activity	NOUN
admet-1885	1	5	of	of	ADP
admet-1885	1	6	flavonoid	flavonoid	PROPN
admet-1885	1	7	derivates	derivate	NOUN
admet-1885	1	8	doi	doi	NOUN
admet-1885	1	9	:	:	PUNCT
admet-1885	1	10	https://doi.org/10.5599/adme	https://doi.org/10.5599/adme	NOUN
admet-1885	1	11	t.1885	t.1885	NOUN
admet-1885	1	12	533	533	NUM
admet-1885	1	13	admet	admet	PROPN
admet-1885	1	14	&	&	CCONJ
admet-1885	1	15	dmpk	dmpk	PROPN
admet-1885	1	16	11(4	11(4	NUM
admet-1885	1	17	)	)	PUNCT
admet-1885	1	18	(	(	PUNCT
admet-1885	1	19	2023	2023	NUM
admet-1885	1	20	)	)	PUNCT
admet-1885	1	21	533	533	NUM
admet-1885	1	22	-	-	SYM
admet-1885	1	23	550	550	NUM
admet-1885	1	24	;	;	PUNCT
admet-1885	1	25	doi	doi	NOUN
admet-1885	1	26	:	:	PUNCT
admet-1885	1	27	https://doi.org/10.5599/admet.1885	https://doi.org/10.5599/admet.1885	NOUN
admet-1885	1	28	open	open	ADJ
admet-1885	1	29	access	access	NOUN
admet-1885	1	30	:	:	PUNCT
admet-1885	1	31	issn	issn	PROPN
admet-1885	1	32	:	:	PUNCT
admet-1885	1	33	1848	1848	NUM
admet-1885	1	34	-	-	SYM
admet-1885	1	35	7718	7718	NUM
admet-1885	1	36	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-1885	1	37	original	original	ADJ
admet-1885	1	38	scientific	scientific	ADJ
admet-1885	1	39	paper	paper	NOUN
admet-1885	1	40	enhancement	enhancement	NOUN
admet-1885	1	41	of	of	ADP
admet-1885	1	42	apixaban	apixaban	PROPN
admet-1885	1	43	's	's	PART
admet-1885	1	44	solubility	solubility	NOUN
admet-1885	1	45	and	and	CCONJ
admet-1885	2	1	dissolution	dissolution	NOUN
admet-1885	2	2	rate	rate	NOUN
admet-1885	2	3	by	by	ADP
admet-1885	2	4	inclusion	inclusion	NOUN
admet-1885	2	5	complex	complex	NOUN
admet-1885	2	6	(	(	PUNCT
admet-1885	2	7	β	β	NOUN
admet-1885	2	8	-	-	NOUN
admet-1885	2	9	cyclodextrin	cyclodextrin	NOUN
admet-1885	2	10	and	and	CCONJ
admet-1885	2	11	hydroxypropyl	hydroxypropyl	VERB
admet-1885	2	12	β	β	NOUN
admet-1885	2	13	-	-	NOUN
admet-1885	2	14	cyclodextrin	cyclodextrin	NOUN
admet-1885	2	15	)	)	PUNCT
admet-1885	2	16	and	and	CCONJ
admet-1885	2	17	computational	computational	ADJ
admet-1885	2	18	calculation	calculation	NOUN
admet-1885	2	19	of	of	ADP
admet-1885	2	20	their	their	PRON
admet-1885	2	21	inclusion	inclusion	NOUN
admet-1885	2	22	complexes	complexe	VERB
admet-1885	2	23	zainab	zainab	PROPN
admet-1885	2	24	n.	n.	PROPN
admet-1885	2	25	salman1	salman1	PROPN
admet-1885	2	26	,	,	PUNCT
admet-1885	2	27	israa	israa	ADJ
admet-1885	2	28	al	al	PROPN
admet-1885	2	29	-	-	PUNCT
admet-1885	2	30	ani1	ani1	PROPN
admet-1885	2	31	,	,	PUNCT
admet-1885	2	32	*	*	NUM
admet-1885	2	33	,	,	PUNCT
admet-1885	2	34	khaldun	khaldun	PROPN
admet-1885	2	35	m.	m.	PROPN
admet-1885	2	36	al	al	PROPN
admet-1885	2	37	azzam1,	azzam1,	PROPN
admet-1885	2	38	,	,	PUNCT
admet-1885	2	39	bashar	bashar	PROPN
admet-1885	2	40	j.	j.	PROPN
admet-1885	2	41	m.	m.	PROPN
admet-1885	2	42	majeed1	majeed1	PROPN
admet-1885	2	43	,	,	PUNCT
admet-1885	2	44	hassan	hassan	PROPN
admet-1885	2	45	h.	h.	PROPN
admet-1885	2	46	abdallah2	abdallah2	PROPN
admet-1885	2	47	and	and	CCONJ
admet-1885	2	48	el	el	PROPN
admet-1885	2	49	-	-	PUNCT
admet-1885	2	50	sayed	say	VERB
admet-1885	2	51	negim3,4	negim3,4	PROPN
admet-1885	2	52	1pharmacological	1pharmacological	PROPN
admet-1885	2	53	and	and	CCONJ
admet-1885	2	54	diagnostic	diagnostic	ADJ
admet-1885	2	55	research	research	NOUN
admet-1885	2	56	center	center	NOUN
admet-1885	2	57	(	(	PUNCT
admet-1885	2	58	pdrc	pdrc	NOUN
admet-1885	2	59	)	)	PUNCT
admet-1885	2	60	,	,	PUNCT
admet-1885	2	61	faculty	faculty	NOUN
admet-1885	2	62	of	of	ADP
admet-1885	2	63	pharmacy	pharmacy	NOUN
admet-1885	2	64	,	,	PUNCT
admet-1885	2	65	al	al	PROPN
admet-1885	2	66	-	-	PUNCT
admet-1885	2	67	ahliyya	ahliyya	PROPN
admet-1885	2	68	amman	amman	PROPN
admet-1885	2	69	university	university	PROPN
admet-1885	2	70	,	,	PUNCT
admet-1885	2	71	amman	amman	NOUN
admet-1885	2	72	19328	19328	NUM
admet-1885	2	73	,	,	PUNCT
admet-1885	2	74	jordan	jordan	PROPN
admet-1885	2	75	2chemistry	2chemistry	PROPN
admet-1885	2	76	department	department	PROPN
admet-1885	2	77	,	,	PUNCT
admet-1885	2	78	college	college	NOUN
admet-1885	2	79	of	of	ADP
admet-1885	2	80	education	education	NOUN
admet-1885	2	81	,	,	PUNCT
admet-1885	2	82	salahaddin	salahaddin	VERB
admet-1885	2	83	university	university	NOUN
admet-1885	2	84	-	-	PUNCT
admet-1885	2	85	erbil	erbil	PROPN
admet-1885	2	86	,	,	PUNCT
admet-1885	2	87	iraq	iraq	PROPN
admet-1885	2	88	.	.	PUNCT
admet-1885	3	1	3school	3school	NUM
admet-1885	3	2	of	of	ADP
admet-1885	3	3	materials	material	NOUN
admet-1885	3	4	science	science	NOUN
admet-1885	3	5	and	and	CCONJ
admet-1885	3	6	green	green	ADJ
admet-1885	3	7	technologies	technology	NOUN
admet-1885	3	8	,	,	PUNCT
admet-1885	3	9	kazakh	kazakh	PROPN
admet-1885	3	10	-	-	PUNCT
admet-1885	3	11	british	british	PROPN
admet-1885	3	12	technical	technical	PROPN
admet-1885	3	13	university	university	PROPN
admet-1885	3	14	,	,	PUNCT
admet-1885	3	15	st	st	PROPN
admet-1885	3	16	.	.	PROPN
admet-1885	3	17	tole	tole	PROPN
admet-1885	3	18	bi	bi	PROPN
admet-1885	3	19	,	,	PUNCT
admet-1885	3	20	59	59	NUM
admet-1885	3	21	,	,	PUNCT
admet-1885	3	22	almaty	almaty	PROPN
admet-1885	3	23	050000	050000	NUM
admet-1885	3	24	,	,	PUNCT
admet-1885	3	25	kazakhstan	kazakhstan	PROPN
admet-1885	3	26	.	.	PUNCT
admet-1885	4	1	4school	4school	NUM
admet-1885	4	2	of	of	ADP
admet-1885	4	3	petroleum	petroleum	NOUN
admet-1885	4	4	engineering	engineering	NOUN
admet-1885	4	5	,	,	PUNCT
admet-1885	4	6	satbayev	satbayev	PROPN
admet-1885	4	7	university	university	NOUN
admet-1885	4	8	,	,	PUNCT
admet-1885	4	9	22	22	NUM
admet-1885	4	10	satpayev	satpayev	PROPN
admet-1885	4	11	street	street	PROPN
admet-1885	4	12	,	,	PUNCT
admet-1885	4	13	almaty	almaty	PROPN
admet-1885	4	14	050013	050013	NUM
admet-1885	4	15	,	,	PUNCT
admet-1885	4	16	kazakhstan	kazakhstan	PROPN
admet-1885	4	17	corresponding	corresponding	PROPN
admet-1885	4	18	authors	author	NOUN
admet-1885	4	19	:	:	PUNCT
admet-1885	4	20	e-mail:*ialani@ammanu.edu.jo	e-mail:*ialani@ammanu.edu.jo	ADJ
admet-1885	4	21	;	;	PUNCT
admet-1885	4	22	azzamkha@yahoo.com	azzamkha@yahoo.com	CCONJ
admet-1885	4	23	received	receive	VERB
admet-1885	4	24	:	:	PUNCT
admet-1885	4	25	may	may	AUX
admet-1885	4	26	10	10	NUM
admet-1885	4	27	,	,	PUNCT
admet-1885	4	28	2023	2023	NUM
admet-1885	4	29	;	;	PUNCT
admet-1885	4	30	revised	revise	VERB
admet-1885	4	31	:	:	PUNCT
admet-1885	4	32	july	july	PROPN
admet-1885	4	33	31	31	NUM
admet-1885	4	34	,	,	PUNCT
admet-1885	4	35	2023	2023	NUM
admet-1885	4	36	;	;	PUNCT
admet-1885	4	37	published	publish	VERB
admet-1885	4	38	:	:	PUNCT
admet-1885	4	39	august	august	PROPN
admet-1885	4	40	10,2023	10,2023	NUM
admet-1885	4	41	abstract	abstract	ADJ
admet-1885	4	42	background	background	NOUN
admet-1885	4	43	and	and	CCONJ
admet-1885	4	44	purpose	purpose	NOUN
admet-1885	4	45	:	:	PUNCT
admet-1885	4	46	apixaban	apixaban	PROPN
admet-1885	4	47	(	(	PUNCT
admet-1885	4	48	ap	ap	PROPN
admet-1885	4	49	)	)	PUNCT
admet-1885	4	50	is	be	AUX
admet-1885	4	51	a	a	DET
admet-1885	4	52	factor	factor	NOUN
admet-1885	4	53	x	x	NOUN
admet-1885	4	54	inhibitor	inhibitor	NOUN
admet-1885	4	55	,	,	PUNCT
admet-1885	4	56	an	an	DET
admet-1885	4	57	orally	orally	ADV
admet-1885	4	58	active	active	ADJ
admet-1885	4	59	drug	drug	NOUN
admet-1885	4	60	that	that	PRON
admet-1885	4	61	inhibits	inhibit	VERB
admet-1885	4	62	blood	blood	NOUN
admet-1885	4	63	coagulation	coagulation	NOUN
admet-1885	4	64	for	for	ADP
admet-1885	4	65	better	well	ADJ
admet-1885	4	66	prevention	prevention	NOUN
admet-1885	4	67	of	of	ADP
admet-1885	4	68	venous	venous	ADJ
admet-1885	4	69	thromboembolism	thromboembolism	NOUN
admet-1885	4	70	.	.	PUNCT
admet-1885	5	1	it	it	PRON
admet-1885	5	2	has	have	VERB
admet-1885	5	3	poor	poor	ADJ
admet-1885	5	4	solubility	solubility	NOUN
admet-1885	5	5	,	,	PUNCT
admet-1885	5	6	dissolution	dissolution	ADJ
admet-1885	5	7	rate	rate	NOUN
admet-1885	5	8	and	and	CCONJ
admet-1885	5	9	low	low	ADJ
admet-1885	5	10	bioavailability	bioavailability	NOUN
admet-1885	5	11	.	.	PUNCT
admet-1885	6	1	the	the	DET
admet-1885	6	2	aim	aim	NOUN
admet-1885	6	3	of	of	ADP
admet-1885	6	4	this	this	DET
admet-1885	6	5	study	study	NOUN
admet-1885	6	6	was	be	AUX
admet-1885	6	7	to	to	PART
admet-1885	6	8	improve	improve	VERB
admet-1885	6	9	the	the	DET
admet-1885	6	10	aqueous	aqueous	ADJ
admet-1885	6	11	solubility	solubility	NOUN
admet-1885	6	12	and	and	CCONJ
admet-1885	6	13	dissolution	dissolution	NOUN
admet-1885	6	14	rate	rate	NOUN
admet-1885	6	15	of	of	ADP
admet-1885	6	16	oral	oral	ADJ
admet-1885	6	17	ap	ap	PROPN
admet-1885	6	18	as	as	ADP
admet-1885	6	19	a	a	DET
admet-1885	6	20	step	step	NOUN
admet-1885	6	21	to	to	PART
admet-1885	6	22	enhance	enhance	VERB
admet-1885	6	23	its	its	PRON
admet-1885	6	24	bioavailability	bioavailability	NOUN
admet-1885	6	25	by	by	ADP
admet-1885	6	26	preparing	prepare	VERB
admet-1885	6	27	it	it	PRON
admet-1885	6	28	as	as	ADP
admet-1885	6	29	an	an	DET
admet-1885	6	30	inclusion	inclusion	NOUN
admet-1885	6	31	complex	complex	NOUN
admet-1885	6	32	with	with	ADP
admet-1885	6	33	betaand	betaand	ADJ
admet-1885	6	34	hydroxy	hydroxy	NOUN
admet-1885	6	35	propyl	propyl	ADJ
admet-1885	6	36	beta	beta	NOUN
admet-1885	6	37	-	-	PUNCT
admet-1885	6	38	cyclodextrin	cyclodextrin	NOUN
admet-1885	6	39	.	.	PUNCT
admet-1885	7	1	experimental	experimental	ADJ
admet-1885	7	2	approach	approach	NOUN
admet-1885	7	3	:	:	PUNCT
admet-1885	7	4	a	a	DET
admet-1885	7	5	simple	simple	ADJ
admet-1885	7	6	,	,	PUNCT
admet-1885	7	7	rapid	rapid	ADJ
admet-1885	7	8	method	method	NOUN
admet-1885	7	9	of	of	ADP
admet-1885	7	10	analysis	analysis	NOUN
admet-1885	7	11	of	of	ADP
admet-1885	7	12	ap	ap	PROPN
admet-1885	7	13	was	be	AUX
admet-1885	7	14	developed	develop	VERB
admet-1885	7	15	using	use	VERB
admet-1885	7	16	ultraviolet	ultraviolet	ADJ
admet-1885	7	17	spectrophotometry	spectrophotometry	NOUN
admet-1885	7	18	(	(	PUNCT
admet-1885	7	19	uv	uv	NOUN
admet-1885	7	20	)	)	PUNCT
admet-1885	7	21	and	and	CCONJ
admet-1885	7	22	partially	partially	ADV
admet-1885	7	23	validated	validate	VERB
admet-1885	7	24	in	in	ADP
admet-1885	7	25	terms	term	NOUN
admet-1885	7	26	of	of	ADP
admet-1885	7	27	linearity	linearity	NOUN
admet-1885	7	28	,	,	PUNCT
admet-1885	7	29	precision	precision	NOUN
admet-1885	7	30	and	and	CCONJ
admet-1885	7	31	accuracy	accuracy	NOUN
admet-1885	7	32	,	,	PUNCT
admet-1885	7	33	recovery	recovery	NOUN
admet-1885	7	34	,	,	PUNCT
admet-1885	7	35	and	and	CCONJ
admet-1885	7	36	robustness	robustness	NOUN
admet-1885	7	37	.	.	PUNCT
admet-1885	8	1	ap	ap	PROPN
admet-1885	8	2	was	be	AUX
admet-1885	8	3	prepared	prepare	VERB
admet-1885	8	4	as	as	ADP
admet-1885	8	5	a	a	DET
admet-1885	8	6	complex	complex	NOUN
admet-1885	8	7	with	with	ADP
admet-1885	8	8	beta	beta	ADJ
admet-1885	8	9	cyclodextrin	cyclodextrin	NOUN
admet-1885	8	10	(	(	PUNCT
admet-1885	8	11	βcd	βcd	NOUN
admet-1885	8	12	)	)	PUNCT
admet-1885	8	13	and	and	CCONJ
admet-1885	8	14	hydroxy	hydroxy	NOUN
admet-1885	8	15	propyl	propyl	ADJ
admet-1885	8	16	beta	beta	ADJ
admet-1885	8	17	cyclodextrin	cyclodextrin	NOUN
admet-1885	8	18	(	(	PUNCT
admet-1885	8	19	hpβcd	hpβcd	ADV
admet-1885	8	20	)	)	PUNCT
admet-1885	8	21	in	in	ADP
admet-1885	8	22	weight	weight	NOUN
admet-1885	8	23	ratios	ratio	NOUN
admet-1885	8	24	1:1	1:1	NUM
admet-1885	8	25	,	,	PUNCT
admet-1885	8	26	1:2	1:2	NUM
admet-1885	8	27	,	,	PUNCT
admet-1885	8	28	and	and	CCONJ
admet-1885	8	29	1:3	1:3	NUM
admet-1885	8	30	by	by	ADP
admet-1885	8	31	kneading	kneading	NOUN
admet-1885	8	32	,	,	PUNCT
admet-1885	8	33	solvent	solvent	ADJ
admet-1885	8	34	evaporation	evaporation	NOUN
admet-1885	8	35	and	and	CCONJ
admet-1885	8	36	spray	spray	VERB
admet-1885	8	37	drying	dry	VERB
admet-1885	8	38	methods	method	NOUN
admet-1885	8	39	and	and	CCONJ
admet-1885	8	40	characterized	characterize	VERB
admet-1885	8	41	by	by	ADP
admet-1885	8	42	fourier	fourier	ADJ
admet-1885	8	43	transfer	transfer	NOUN
admet-1885	8	44	infra	infra	NOUN
admet-1885	8	45	-	-	PUNCT
admet-1885	8	46	red	red	ADJ
admet-1885	8	47	(	(	PUNCT
admet-1885	8	48	ftir	ftir	PROPN
admet-1885	8	49	)	)	PUNCT
admet-1885	8	50	,	,	PUNCT
admet-1885	8	51	differential	differential	NOUN
admet-1885	8	52	scanning	scanning	NOUN
admet-1885	8	53	calorimetry	calorimetry	NOUN
admet-1885	8	54	(	(	PUNCT
admet-1885	8	55	dsc	dsc	NOUN
admet-1885	8	56	)	)	PUNCT
admet-1885	8	57	,	,	PUNCT
admet-1885	8	58	and	and	CCONJ
admet-1885	8	59	percent	percent	NOUN
admet-1885	8	60	drug	drug	NOUN
admet-1885	8	61	content	content	NOUN
admet-1885	8	62	in	in	ADP
admet-1885	8	63	each	each	PRON
admet-1885	8	64	of	of	ADP
admet-1885	8	65	the	the	DET
admet-1885	8	66	prepared	prepared	ADJ
admet-1885	8	67	complex	complex	NOUN
admet-1885	8	68	.	.	PUNCT
admet-1885	9	1	using	use	VERB
admet-1885	9	2	the	the	DET
admet-1885	9	3	computer	computer	NOUN
admet-1885	9	4	simulati	simulati	NOUN
admet-1885	9	5	on	on	ADP
admet-1885	9	6	,	,	PUNCT
admet-1885	9	7	the	the	DET
admet-1885	9	8	interactions	interaction	NOUN
admet-1885	9	9	of	of	ADP
admet-1885	9	10	ap	ap	PROPN
admet-1885	9	11	with	with	ADP
admet-1885	9	12	βcd	βcd	NOUN
admet-1885	10	1	and	and	CCONJ
admet-1885	10	2	hpβcd	hpβcd	PROPN
admet-1885	10	3	were	be	AUX
admet-1885	10	4	investigated	investigate	VERB
admet-1885	10	5	.	.	PUNCT
admet-1885	11	1	key	key	ADJ
admet-1885	11	2	results	result	NOUN
admet-1885	11	3	:	:	PUNCT
admet-1885	11	4	the	the	DET
admet-1885	11	5	phase	phase	NOUN
admet-1885	11	6	solubility	solubility	NOUN
admet-1885	11	7	study	study	NOUN
admet-1885	11	8	showed	show	VERB
admet-1885	11	9	that	that	SCONJ
admet-1885	11	10	the	the	DET
admet-1885	11	11	solubility	solubility	NOUN
admet-1885	11	12	of	of	ADP
admet-1885	11	13	ap	ap	PROPN
admet-1885	11	14	was	be	AUX
admet-1885	11	15	greatly	greatly	ADV
admet-1885	11	16	enhanced	enhance	VERB
admet-1885	11	17	from	from	ADP
admet-1885	11	18	54×10	54×10	NUM
admet-1885	11	19	-3	-3	INTJ
admet-1885	11	20	mmol	mmol	NOUN
admet-1885	11	21	/l	/l	PUNCT
admet-1885	11	22	to	to	ADP
admet-1885	11	23	66	66	NUM
admet-1885	11	24	mmol	mmol	NOUN
admet-1885	11	25	/	/	SYM
admet-1885	11	26	l	l	NOUN
admet-1885	11	27	using	use	VERB
admet-1885	11	28	hpβcd	hpβcd	ADJ
admet-1885	11	29	with	with	ADP
admet-1885	11	30	acceptable	acceptable	ADJ
admet-1885	11	31	stability	stability	NOUN
admet-1885	11	32	constant	constant	ADJ
admet-1885	11	33	.	.	PUNCT
admet-1885	12	1	computer	computer	NOUN
admet-1885	12	2	docking	docking	NOUN
admet-1885	12	3	supports	support	VERB
admet-1885	12	4	the	the	DET
admet-1885	12	5	formation	formation	NOUN
admet-1885	12	6	of	of	ADP
admet-1885	12	7	a	a	DET
admet-1885	12	8	stable	stable	ADJ
admet-1885	12	9	1:1	1:1	NUM
admet-1885	12	10	complex	complex	NOUN
admet-1885	12	11	between	between	ADP
admet-1885	12	12	ap	ap	PROPN
admet-1885	12	13	and	and	CCONJ
admet-1885	12	14	cd	cd	PROPN
admet-1885	12	15	’s	’s	PART
admet-1885	12	16	.	.	PUNCT
admet-1885	13	1	the	the	DET
admet-1885	13	2	dissolution	dissolution	PROPN
admet-1885	13	3	test	test	NOUN
admet-1885	13	4	results	result	NOUN
admet-1885	13	5	showed	show	VERB
admet-1885	13	6	that	that	SCONJ
admet-1885	13	7	the	the	DET
admet-1885	13	8	complex	complex	NOUN
admet-1885	13	9	gave	give	VERB
admet-1885	13	10	a	a	DET
admet-1885	13	11	significantly	significantly	ADV
admet-1885	13	12	higher	high	ADJ
admet-1885	13	13	percentage	percentage	NOUN
admet-1885	13	14	of	of	ADP
admet-1885	13	15	drug	drug	NOUN
admet-1885	13	16	release	release	NOUN
admet-1885	13	17	(	(	PUNCT
admet-1885	13	18	95	95	NUM
admet-1885	13	19	%	%	NOUN
admet-1885	13	20	)	)	PUNCT
admet-1885	13	21	over	over	ADP
admet-1885	13	22	one	one	NUM
admet-1885	13	23	hour	hour	NOUN
admet-1885	13	24	compared	compare	VERB
admet-1885	13	25	to	to	ADP
admet-1885	13	26	the	the	DET
admet-1885	13	27	free	free	PROPN
admet-1885	13	28	ap	ap	PROPN
admet-1885	13	29	(	(	PUNCT
admet-1885	13	30	60	60	NUM
admet-1885	13	31	%	%	NOUN
admet-1885	13	32	)	)	PUNCT
admet-1885	13	33	(	(	PUNCT
admet-1885	13	34	p<0.05	p<0.05	NOUN
admet-1885	13	35	)	)	PUNCT
admet-1885	13	36	.	.	PUNCT
admet-1885	14	1	conclusion	conclusion	NOUN
admet-1885	14	2	:	:	PUNCT
admet-1885	14	3	aphpβcd	aphpβcd	PROPN
admet-1885	14	4	complex	complex	NOUN
admet-1885	14	5	in	in	ADP
admet-1885	14	6	the	the	DET
admet-1885	14	7	ratio	ratio	NOUN
admet-1885	14	8	of	of	ADP
admet-1885	14	9	1:2	1:2	NUM
admet-1885	14	10	(	(	PUNCT
admet-1885	14	11	w	w	PROPN
admet-1885	14	12	/	/	SYM
admet-1885	14	13	w	w	NOUN
admet-1885	14	14	)	)	PUNCT
admet-1885	14	15	can	can	AUX
admet-1885	14	16	significantly	significantly	ADV
admet-1885	14	17	improve	improve	VERB
admet-1885	14	18	the	the	DET
admet-1885	14	19	solubility	solubility	NOUN
admet-1885	14	20	and	and	CCONJ
admet-1885	14	21	in	in	ADP
admet-1885	14	22	vitro	vitro	X
admet-1885	14	23	dissolution	dissolution	NOUN
admet-1885	14	24	rate	rate	NOUN
admet-1885	14	25	of	of	ADP
admet-1885	14	26	ap	ap	PROPN
admet-1885	14	27	.	.	PUNCT
admet-1885	15	1	©	©	PROPN
admet-1885	15	2	2023	2023	NUM
admet-1885	15	3	by	by	ADP
admet-1885	15	4	the	the	DET
admet-1885	15	5	authors	author	NOUN
admet-1885	15	6	.	.	PUNCT
admet-1885	16	1	this	this	DET
admet-1885	16	2	article	article	NOUN
admet-1885	16	3	is	be	AUX
admet-1885	16	4	an	an	DET
admet-1885	16	5	open	open	ADJ
admet-1885	16	6	-	-	PUNCT
admet-1885	16	7	access	access	NOUN
admet-1885	16	8	article	article	NOUN
admet-1885	16	9	distributed	distribute	VERB
admet-1885	16	10	under	under	ADP
admet-1885	16	11	the	the	DET
admet-1885	16	12	terms	term	NOUN
admet-1885	16	13	and	and	CCONJ
admet-1885	16	14	conditions	condition	NOUN
admet-1885	16	15	of	of	ADP
admet-1885	16	16	the	the	DET
admet-1885	16	17	creative	creative	ADJ
admet-1885	16	18	commons	common	NOUN
admet-1885	16	19	attribution	attribution	NOUN
admet-1885	16	20	license	license	NOUN
admet-1885	16	21	(	(	PUNCT
admet-1885	16	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-1885	16	23	)	)	PUNCT
admet-1885	16	24	.	.	PUNCT
admet-1885	17	1	keywords	keyword	NOUN
admet-1885	17	2	apixaban	apixaban	ADJ
admet-1885	17	3	;	;	PUNCT
admet-1885	17	4	hpβcd	hpβcd	PRON
admet-1885	17	5	,	,	PUNCT
admet-1885	17	6	βcd	βcd	NOUN
admet-1885	17	7	,	,	PUNCT
admet-1885	17	8	capsule	capsule	NOUN
admet-1885	17	9	,	,	PUNCT
admet-1885	17	10	bioavailability	bioavailability	NOUN
admet-1885	17	11	,	,	PUNCT
admet-1885	17	12	solubility	solubility	NOUN
admet-1885	17	13	introduction	introduction	NOUN
admet-1885	17	14	the	the	DET
admet-1885	17	15	problem	problem	NOUN
admet-1885	17	16	of	of	ADP
admet-1885	17	17	low	low	ADJ
admet-1885	17	18	solubility	solubility	NOUN
admet-1885	17	19	is	be	AUX
admet-1885	17	20	a	a	DET
admet-1885	17	21	major	major	ADJ
admet-1885	17	22	challenge	challenge	NOUN
admet-1885	17	23	in	in	ADP
admet-1885	17	24	the	the	DET
admet-1885	17	25	formulation	formulation	NOUN
admet-1885	17	26	of	of	ADP
admet-1885	17	27	new	new	ADJ
admet-1885	17	28	drugs	drug	NOUN
admet-1885	17	29	[	[	X
admet-1885	17	30	1	1	NUM
admet-1885	17	31	]	]	PUNCT
admet-1885	17	32	.	.	PUNCT
admet-1885	18	1	poor	poor	ADJ
admet-1885	18	2	solubility	solubility	NOUN
admet-1885	18	3	might	might	AUX
admet-1885	18	4	lead	lead	VERB
admet-1885	18	5	to	to	PART
admet-1885	18	6	slow	slow	VERB
admet-1885	18	7	and	and	CCONJ
admet-1885	18	8	incomplete	incomplete	ADJ
admet-1885	18	9	absorption	absorption	NOUN
admet-1885	18	10	and	and	CCONJ
admet-1885	18	11	low	low	ADJ
admet-1885	18	12	bioavailability	bioavailability	NOUN
admet-1885	18	13	[	[	X
admet-1885	18	14	2,3	2,3	NUM
admet-1885	18	15	]	]	PUNCT
admet-1885	18	16	.	.	PUNCT
admet-1885	19	1	the	the	DET
admet-1885	19	2	enhancement	enhancement	NOUN
admet-1885	19	3	of	of	ADP
admet-1885	19	4	drug	drug	NOUN
admet-1885	19	5	https://doi.org/10.5599/admet.1885	https://doi.org/10.5599/admet.1885	NOUN
admet-1885	19	6	https://doi.org/10.5599/admet.1885	https://doi.org/10.5599/admet.1885	NOUN
admet-1885	19	7	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-1885	19	8	mailto:ialani@ammanu.edu.jo	mailto:ialani@ammanu.edu.jo	NOUN
admet-1885	19	9	mailto:azzamkha@yahoo.com	mailto:azzamkha@yahoo.com	X
admet-1885	19	10	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-1885	19	11	z.	z.	PROPN
admet-1885	19	12	n.	n.	PROPN
admet-1885	19	13	salman	salman	PROPN
admet-1885	19	14	et	et	PROPN
admet-1885	19	15	al	al	PROPN
admet-1885	19	16	.	.	PROPN
admet-1885	19	17	admet	admet	PROPN
admet-1885	19	18	&	&	CCONJ
admet-1885	19	19	dmpk	dmpk	PROPN
admet-1885	19	20	11(4	11(4	NUM
admet-1885	19	21	)	)	PUNCT
admet-1885	19	22	(	(	PUNCT
admet-1885	19	23	2023	2023	NUM
admet-1885	19	24	)	)	PUNCT
admet-1885	19	25	533	533	NUM
admet-1885	19	26	-	-	SYM
admet-1885	19	27	550	550	NUM
admet-1885	19	28	534	534	NUM
admet-1885	19	29	solubility	solubility	NOUN
admet-1885	19	30	,	,	PUNCT
admet-1885	19	31	thereby	thereby	ADV
admet-1885	19	32	enhancing	enhance	VERB
admet-1885	19	33	its	its	PRON
admet-1885	19	34	oral	oral	ADJ
admet-1885	19	35	bioavailability	bioavailability	NOUN
admet-1885	19	36	,	,	PUNCT
admet-1885	19	37	remains	remain	VERB
admet-1885	19	38	one	one	NUM
admet-1885	19	39	of	of	ADP
admet-1885	19	40	the	the	DET
admet-1885	19	41	most	most	ADV
admet-1885	19	42	challenging	challenging	ADJ
admet-1885	19	43	steps	step	NOUN
admet-1885	19	44	of	of	ADP
admet-1885	19	45	the	the	DET
admet-1885	19	46	drug	drug	NOUN
admet-1885	19	47	development	development	NOUN
admet-1885	19	48	process	process	NOUN
admet-1885	19	49	,	,	PUNCT
admet-1885	19	50	especially	especially	ADV
admet-1885	19	51	for	for	ADP
admet-1885	19	52	oral	oral	ADJ
admet-1885	19	53	administrated	administrate	VERB
admet-1885	19	54	drug	drug	NOUN
admet-1885	19	55	delivery	delivery	NOUN
admet-1885	19	56	systems	system	NOUN
admet-1885	19	57	.	.	PUNCT
admet-1885	20	1	many	many	ADJ
admet-1885	20	2	techniques	technique	NOUN
admet-1885	20	3	can	can	AUX
admet-1885	20	4	be	be	AUX
admet-1885	20	5	utilized	utilize	VERB
admet-1885	20	6	for	for	ADP
admet-1885	20	7	solubility	solubility	NOUN
admet-1885	20	8	enhancement	enhancement	NOUN
admet-1885	20	9	,	,	PUNCT
admet-1885	20	10	especially	especially	ADV
admet-1885	20	11	those	those	PRON
admet-1885	20	12	of	of	ADP
admet-1885	20	13	class	class	NOUN
admet-1885	20	14	ii	ii	PROPN
admet-1885	20	15	and	and	CCONJ
admet-1885	20	16	iv	iv	NUM
admet-1885	20	17	bcs	bcs	NOUN
admet-1885	20	18	(	(	PUNCT
admet-1885	20	19	biopharmaceutical	biopharmaceutical	NOUN
admet-1885	20	20	classification	classification	NOUN
admet-1885	20	21	system	system	NOUN
admet-1885	20	22	)	)	PUNCT
admet-1885	20	23	drugs	drug	NOUN
admet-1885	20	24	,	,	PUNCT
admet-1885	20	25	to	to	PART
admet-1885	20	26	improve	improve	VERB
admet-1885	20	27	their	their	PRON
admet-1885	20	28	oral	oral	ADJ
admet-1885	20	29	bioavailability	bioavailability	NOUN
admet-1885	20	30	.	.	PUNCT
admet-1885	21	1	techniques	technique	NOUN
admet-1885	21	2	include	include	VERB
admet-1885	21	3	cosolvents	cosolvent	NOUN
admet-1885	21	4	,	,	PUNCT
admet-1885	21	5	micronization	micronization	NOUN
admet-1885	21	6	,	,	PUNCT
admet-1885	21	7	changing	change	VERB
admet-1885	21	8	in	in	ADP
admet-1885	21	9	the	the	DET
admet-1885	21	10	dielectric	dielectric	ADJ
admet-1885	21	11	constant	constant	NOUN
admet-1885	21	12	of	of	ADP
admet-1885	21	13	the	the	DET
admet-1885	21	14	solvent	solvent	NOUN
admet-1885	21	15	,	,	PUNCT
admet-1885	21	16	use	use	NOUN
admet-1885	21	17	of	of	ADP
admet-1885	21	18	amorphous	amorphous	ADJ
admet-1885	21	19	forms	form	NOUN
admet-1885	21	20	,	,	PUNCT
admet-1885	21	21	chemical	chemical	NOUN
admet-1885	21	22	modification	modification	NOUN
admet-1885	21	23	of	of	ADP
admet-1885	21	24	the	the	DET
admet-1885	21	25	molecule	molecule	NOUN
admet-1885	21	26	,	,	PUNCT
admet-1885	21	27	use	use	NOUN
admet-1885	21	28	of	of	ADP
admet-1885	21	29	surfactants	surfactant	NOUN
admet-1885	21	30	,	,	PUNCT
admet-1885	21	31	solid	solid	ADJ
admet-1885	21	32	dispersion	dispersion	NOUN
admet-1885	21	33	techniques	technique	NOUN
admet-1885	21	34	,	,	PUNCT
admet-1885	21	35	eutectic	eutectic	ADJ
admet-1885	21	36	mixtures	mixture	NOUN
admet-1885	21	37	,	,	PUNCT
admet-1885	21	38	inclusion	inclusion	NOUN
admet-1885	21	39	complex	complex	NOUN
admet-1885	21	40	,	,	PUNCT
admet-1885	21	41	manipulation	manipulation	NOUN
admet-1885	21	42	of	of	ADP
admet-1885	21	43	ph	ph	NOUN
admet-1885	21	44	of	of	ADP
admet-1885	21	45	solvent	solvent	NOUN
admet-1885	21	46	,	,	PUNCT
admet-1885	21	47	utilization	utilization	NOUN
admet-1885	21	48	of	of	ADP
admet-1885	21	49	hydrates	hydrate	NOUN
admet-1885	21	50	or	or	CCONJ
admet-1885	21	51	solvates	solvate	NOUN
admet-1885	21	52	,	,	PUNCT
admet-1885	21	53	utilization	utilization	NOUN
admet-1885	21	54	of	of	ADP
admet-1885	21	55	soluble	soluble	ADJ
admet-1885	21	56	prodrugs	prodrug	NOUN
admet-1885	21	57	,	,	PUNCT
admet-1885	21	58	application	application	NOUN
admet-1885	21	59	of	of	ADP
admet-1885	21	60	ultrasonic	ultrasonic	ADJ
admet-1885	21	61	waves	wave	NOUN
admet-1885	21	62	,	,	PUNCT
admet-1885	21	63	functional	functional	ADJ
admet-1885	21	64	polymer	polymer	NOUN
admet-1885	21	65	technology	technology	NOUN
admet-1885	21	66	,	,	PUNCT
admet-1885	21	67	and	and	CCONJ
admet-1885	21	68	some	some	DET
admet-1885	21	69	others	other	NOUN
admet-1885	21	70	.	.	PUNCT
admet-1885	22	1	novel	novel	ADJ
admet-1885	22	2	drug	drug	NOUN
admet-1885	22	3	delivery	delivery	NOUN
admet-1885	22	4	technologies	technology	NOUN
admet-1885	22	5	used	use	VERB
admet-1885	22	6	in	in	ADP
admet-1885	22	7	recent	recent	ADJ
admet-1885	22	8	years	year	NOUN
admet-1885	22	9	for	for	ADP
admet-1885	22	10	solubility	solubility	NOUN
admet-1885	22	11	enhancement	enhancement	NOUN
admet-1885	22	12	of	of	ADP
admet-1885	22	13	insoluble	insoluble	ADJ
admet-1885	22	14	drugs	drug	NOUN
admet-1885	22	15	are	be	AUX
admet-1885	22	16	size	size	NOUN
admet-1885	22	17	reduction	reduction	NOUN
admet-1885	22	18	technologies	technology	NOUN
admet-1885	22	19	,	,	PUNCT
admet-1885	22	20	lipid	lipid	NOUN
admet-1885	22	21	-	-	PUNCT
admet-1885	22	22	based	base	VERB
admet-1885	22	23	delivery	delivery	NOUN
admet-1885	22	24	systems	system	NOUN
admet-1885	22	25	,	,	PUNCT
admet-1885	22	26	micellar	micellar	NOUN
admet-1885	22	27	technologies	technology	NOUN
admet-1885	22	28	,	,	PUNCT
admet-1885	22	29	and	and	CCONJ
admet-1885	22	30	porous	porous	ADJ
admet-1885	22	31	microparticle	microparticle	NOUN
admet-1885	22	32	technology	technology	NOUN
admet-1885	22	33	.	.	PUNCT
admet-1885	23	1	the	the	DET
admet-1885	23	2	selection	selection	NOUN
admet-1885	23	3	of	of	ADP
admet-1885	23	4	which	which	DET
admet-1885	23	5	method	method	NOUN
admet-1885	23	6	would	would	AUX
admet-1885	23	7	be	be	AUX
admet-1885	23	8	based	base	VERB
admet-1885	23	9	on	on	ADP
admet-1885	23	10	certain	certain	ADJ
admet-1885	23	11	criteria	criterion	NOUN
admet-1885	23	12	such	such	ADJ
admet-1885	23	13	as	as	ADP
admet-1885	23	14	properties	property	NOUN
admet-1885	23	15	of	of	ADP
admet-1885	23	16	a	a	DET
admet-1885	23	17	drug	drug	NOUN
admet-1885	23	18	,	,	PUNCT
admet-1885	23	19	nature	nature	NOUN
admet-1885	23	20	of	of	ADP
admet-1885	23	21	excipients	excipient	NOUN
admet-1885	23	22	to	to	PART
admet-1885	23	23	be	be	AUX
admet-1885	23	24	chosen	choose	VERB
admet-1885	23	25	,	,	PUNCT
admet-1885	23	26	and	and	CCONJ
admet-1885	23	27	nature	nature	NOUN
admet-1885	23	28	of	of	ADP
admet-1885	23	29	the	the	DET
admet-1885	23	30	desired	desire	VERB
admet-1885	23	31	dosage	dosage	NOUN
admet-1885	23	32	form	form	NOUN
admet-1885	23	33	as	as	ADV
admet-1885	23	34	well	well	ADV
admet-1885	23	35	as	as	ADP
admet-1885	23	36	cost	cost	NOUN
admet-1885	23	37	and	and	CCONJ
admet-1885	23	38	industrial	industrial	ADJ
admet-1885	23	39	issues	issue	NOUN
admet-1885	23	40	[	[	X
admet-1885	23	41	4	4	NUM
admet-1885	23	42	-	-	SYM
admet-1885	23	43	6	6	NUM
admet-1885	23	44	]	]	PUNCT
admet-1885	23	45	.	.	PUNCT
admet-1885	24	1	apixaban	apixaban	PROPN
admet-1885	24	2	(	(	PUNCT
admet-1885	24	3	ap	ap	PROPN
admet-1885	24	4	)	)	PUNCT
admet-1885	24	5	was	be	AUX
admet-1885	24	6	developed	develop	VERB
admet-1885	24	7	by	by	ADP
admet-1885	24	8	bristol	bristol	PROPN
admet-1885	24	9	-	-	PUNCT
admet-1885	24	10	myers	myers	PROPN
admet-1885	24	11	squibb	squibb	PROPN
admet-1885	24	12	using	use	VERB
admet-1885	24	13	the	the	DET
admet-1885	24	14	trade	trade	NOUN
admet-1885	24	15	name	name	NOUN
admet-1885	24	16	of	of	ADP
admet-1885	24	17	“	"	PUNCT
admet-1885	24	18	eliquis	eliquis	NOUN
admet-1885	24	19	”	"	PUNCT
admet-1885	24	20	,	,	PUNCT
admet-1885	24	21	with	with	ADP
admet-1885	24	22	high	high	ADJ
admet-1885	24	23	potency	potency	NOUN
admet-1885	24	24	and	and	CCONJ
admet-1885	24	25	selectivity	selectivity	NOUN
admet-1885	24	26	,	,	PUNCT
admet-1885	24	27	and	and	CCONJ
admet-1885	24	28	is	be	AUX
admet-1885	24	29	a	a	DET
admet-1885	24	30	very	very	ADV
admet-1885	24	31	effective	effective	ADJ
admet-1885	24	32	inhibitor	inhibitor	NOUN
admet-1885	24	33	for	for	ADP
admet-1885	24	34	the	the	DET
admet-1885	24	35	blood	blood	NOUN
admet-1885	24	36	coagulation	coagulation	NOUN
admet-1885	24	37	factor	factor	NOUN
admet-1885	24	38	xa	xa	PROPN
admet-1885	25	1	[	[	X
admet-1885	25	2	7	7	NUM
admet-1885	25	3	]	]	PUNCT
admet-1885	25	4	.	.	PUNCT
admet-1885	26	1	it	it	PRON
admet-1885	26	2	is	be	AUX
admet-1885	26	3	an	an	DET
admet-1885	26	4	orally	orally	ADV
admet-1885	26	5	developed	develop	VERB
admet-1885	26	6	drug	drug	NOUN
admet-1885	26	7	that	that	PRON
admet-1885	26	8	inhibits	inhibit	VERB
admet-1885	26	9	blood	blood	NOUN
admet-1885	26	10	coagulation	coagulation	NOUN
admet-1885	26	11	for	for	ADP
admet-1885	26	12	better	well	ADJ
admet-1885	26	13	prevention	prevention	NOUN
admet-1885	26	14	of	of	ADP
admet-1885	26	15	venous	venous	ADJ
admet-1885	26	16	thromboembolism	thromboembolism	NOUN
admet-1885	26	17	(	(	PUNCT
admet-1885	26	18	vte	vte	NOUN
admet-1885	26	19	)	)	PUNCT
admet-1885	26	20	after	after	ADP
admet-1885	26	21	hip	hip	NOUN
admet-1885	26	22	or	or	CCONJ
admet-1885	26	23	knee	knee	NOUN
admet-1885	26	24	replacement	replacement	NOUN
admet-1885	26	25	surgery	surgery	NOUN
admet-1885	26	26	as	as	ADP
admet-1885	26	27	an	an	DET
admet-1885	26	28	alternative	alternative	NOUN
admet-1885	26	29	to	to	ADP
admet-1885	26	30	previously	previously	ADV
admet-1885	26	31	used	use	VERB
admet-1885	26	32	warfarin	warfarin	NOUN
admet-1885	26	33	[	[	X
admet-1885	26	34	8,9	8,9	NUM
admet-1885	26	35	]	]	PUNCT
admet-1885	26	36	.	.	PUNCT
admet-1885	27	1	it	it	PRON
admet-1885	27	2	is	be	AUX
admet-1885	27	3	also	also	ADV
admet-1885	27	4	indicated	indicate	VERB
admet-1885	27	5	for	for	ADP
admet-1885	27	6	the	the	DET
admet-1885	27	7	prevention	prevention	NOUN
admet-1885	27	8	and	and	CCONJ
admet-1885	27	9	treatment	treatment	NOUN
admet-1885	27	10	of	of	ADP
admet-1885	27	11	other	other	ADJ
admet-1885	27	12	thromboembolic	thromboembolic	ADJ
admet-1885	27	13	diseases	disease	NOUN
admet-1885	27	14	.	.	PUNCT
admet-1885	28	1	ap	ap	PROPN
admet-1885	28	2	is	be	AUX
admet-1885	28	3	{	{	PUNCT
admet-1885	28	4	1-(4	1-(4	NUM
admet-1885	28	5	-	-	PUNCT
admet-1885	28	6	methoxyphenyl)-7	methoxyphenyl)-7	NOUN
admet-1885	28	7	-	-	PUNCT
admet-1885	28	8	oxo-2)-4]-6	oxo-2)-4]-6	NOUN
admet-1885	28	9	-	-	PUNCT
admet-1885	28	10	oxopiperidin-1	oxopiperidin-1	NUM
admet-1885	28	11	-	-	PUNCT
admet-1885	28	12	yl)phenyl]-5,4	yl)phenyl]-5,4	NOUN
admet-1885	28	13	-	-	PUNCT
admet-1885	28	14	dihydropyrazolo-[3,4	dihydropyrazolo-[3,4	ADJ
admet-1885	28	15	-	-	PUNCT
admet-1885	28	16	c]-pyridine3	c]-pyridine3	NOUN
admet-1885	28	17	-	-	PUNCT
admet-1885	28	18	carboxamide	carboxamide	NOUN
admet-1885	28	19	}	}	PUNCT
admet-1885	28	20	,	,	PUNCT
admet-1885	28	21	its	its	PRON
admet-1885	28	22	chemical	chemical	NOUN
admet-1885	28	23	structure	structure	NOUN
admet-1885	28	24	is	be	AUX
admet-1885	28	25	shown	show	VERB
admet-1885	28	26	in	in	ADP
admet-1885	28	27	figure	figure	NOUN
admet-1885	28	28	1	1	NUM
admet-1885	29	1	[	[	X
admet-1885	29	2	10	10	NUM
admet-1885	29	3	]	]	PUNCT
admet-1885	29	4	.	.	PUNCT
admet-1885	30	1	ap	ap	PROPN
admet-1885	30	2	has	have	VERB
admet-1885	30	3	a	a	DET
admet-1885	30	4	molecular	molecular	ADJ
admet-1885	30	5	weight	weight	NOUN
admet-1885	30	6	of	of	ADP
admet-1885	30	7	459.5	459.5	NUM
admet-1885	30	8	g	g	NOUN
admet-1885	30	9	/	/	SYM
admet-1885	30	10	mol	mol	NOUN
admet-1885	30	11	,	,	PUNCT
admet-1885	30	12	and	and	CCONJ
admet-1885	30	13	the	the	DET
admet-1885	30	14	chemical	chemical	NOUN
admet-1885	30	15	formula	formula	NOUN
admet-1885	30	16	of	of	ADP
admet-1885	30	17	c25h25n5o4	c25h25n5o4	PROPN
admet-1885	30	18	.	.	PUNCT
admet-1885	31	1	it	it	PRON
admet-1885	31	2	is	be	AUX
admet-1885	31	3	a	a	DET
admet-1885	31	4	white	white	ADJ
admet-1885	31	5	to	to	PART
admet-1885	31	6	pale	pale	ADJ
admet-1885	31	7	yellow	yellow	ADJ
admet-1885	31	8	powder	powder	NOUN
admet-1885	31	9	with	with	ADP
admet-1885	31	10	a	a	DET
admet-1885	31	11	melting	melting	NOUN
admet-1885	31	12	point	point	NOUN
admet-1885	31	13	equal	equal	ADJ
admet-1885	31	14	to	to	ADP
admet-1885	31	15	326	326	NUM
admet-1885	31	16	°	°	NOUN
admet-1885	31	17	c	c	NOUN
admet-1885	31	18	.	.	PUNCT
admet-1885	32	1	it	it	PRON
admet-1885	32	2	has	have	VERB
admet-1885	32	3	good	good	ADJ
admet-1885	32	4	solubility	solubility	NOUN
admet-1885	32	5	in	in	ADP
admet-1885	32	6	dimethyl	dimethyl	NOUN
admet-1885	32	7	sulfoxide	sulfoxide	NOUN
admet-1885	32	8	and	and	CCONJ
admet-1885	32	9	dimethylformamide	dimethylformamide	NOUN
admet-1885	32	10	but	but	CCONJ
admet-1885	32	11	low	low	ADJ
admet-1885	32	12	water	water	NOUN
admet-1885	32	13	solubility	solubility	NOUN
admet-1885	32	14	of	of	ADP
admet-1885	32	15	(	(	PUNCT
admet-1885	32	16	0.028	0.028	NUM
admet-1885	32	17	mg	mg	PROPN
admet-1885	32	18	/	/	SYM
admet-1885	32	19	ml	ml	NOUN
admet-1885	32	20	at	at	ADP
admet-1885	32	21	24	24	NUM
admet-1885	32	22	°	°	NOUN
admet-1885	32	23	c	c	NOUN
admet-1885	32	24	)	)	PUNCT
admet-1885	32	25	.	.	PUNCT
admet-1885	33	1	different	different	ADJ
admet-1885	33	2	references	reference	NOUN
admet-1885	33	3	give	give	VERB
admet-1885	33	4	different	different	ADJ
admet-1885	33	5	solubility	solubility	NOUN
admet-1885	33	6	values	value	NOUN
admet-1885	33	7	for	for	ADP
admet-1885	33	8	ap	ap	PROPN
admet-1885	34	1	[	[	X
admet-1885	34	2	11	11	NUM
admet-1885	34	3	]	]	PUNCT
admet-1885	34	4	.	.	PUNCT
admet-1885	35	1	figure	figure	NOUN
admet-1885	35	2	1	1	NUM
admet-1885	35	3	.	.	PUNCT
admet-1885	36	1	the	the	DET
admet-1885	36	2	chemical	chemical	ADJ
admet-1885	36	3	structure	structure	NOUN
admet-1885	36	4	of	of	ADP
admet-1885	36	5	ap	ap	PROPN
admet-1885	36	6	.	.	PUNCT
admet-1885	37	1	ap	ap	PROPN
admet-1885	37	2	is	be	AUX
admet-1885	37	3	absorbed	absorb	VERB
admet-1885	37	4	along	along	ADP
admet-1885	37	5	the	the	DET
admet-1885	37	6	gastrointestinal	gastrointestinal	ADJ
admet-1885	37	7	tract	tract	NOUN
admet-1885	37	8	git	git	NOUN
admet-1885	37	9	with	with	ADP
admet-1885	37	10	the	the	DET
admet-1885	37	11	distal	distal	ADJ
admet-1885	37	12	part	part	NOUN
admet-1885	37	13	and	and	CCONJ
admet-1885	37	14	descending	descend	VERB
admet-1885	37	15	colon	colon	NOUN
admet-1885	37	16	contributes	contribute	VERB
admet-1885	37	17	up	up	ADP
admet-1885	37	18	to	to	PART
admet-1885	37	19	55	55	NUM
admet-1885	37	20	%	%	NOUN
admet-1885	37	21	of	of	ADP
admet-1885	37	22	total	total	ADJ
admet-1885	37	23	absorption	absorption	NOUN
admet-1885	37	24	.	.	PUNCT
admet-1885	38	1	it	it	PRON
admet-1885	38	2	also	also	ADV
admet-1885	38	3	shows	show	VERB
admet-1885	38	4	dissolution	dissolution	ADJ
admet-1885	38	5	limited	limited	ADJ
admet-1885	38	6	absorption	absorption	NOUN
admet-1885	38	7	,	,	PUNCT
admet-1885	38	8	which	which	PRON
admet-1885	38	9	also	also	ADV
admet-1885	38	10	results	result	VERB
admet-1885	38	11	in	in	ADP
admet-1885	38	12	slow	slow	ADJ
admet-1885	38	13	absorption	absorption	NOUN
admet-1885	38	14	,	,	PUNCT
admet-1885	38	15	and	and	CCONJ
admet-1885	38	16	so	so	ADV
admet-1885	38	17	,	,	PUNCT
admet-1885	38	18	cmax	cmax	NOUN
admet-1885	38	19	is	be	AUX
admet-1885	38	20	achieved	achieve	VERB
admet-1885	38	21	in	in	ADP
admet-1885	38	22	3	3	NUM
admet-1885	38	23	5	5	NUM
admet-1885	38	24	hours	hour	NOUN
admet-1885	38	25	,	,	PUNCT
admet-1885	38	26	while	while	SCONJ
admet-1885	38	27	in	in	ADP
admet-1885	38	28	rats	rat	NOUN
admet-1885	38	29	,	,	PUNCT
admet-1885	38	30	absorption	absorption	NOUN
admet-1885	38	31	was	be	AUX
admet-1885	38	32	found	find	VERB
admet-1885	38	33	to	to	PART
admet-1885	38	34	be	be	AUX
admet-1885	38	35	faster	fast	ADV
admet-1885	38	36	and	and	CCONJ
admet-1885	38	37	cmax	cmax	NOUN
admet-1885	38	38	was	be	AUX
admet-1885	38	39	achieved	achieve	VERB
admet-1885	38	40	in	in	ADP
admet-1885	38	41	1	1	NUM
admet-1885	38	42	2	2	NUM
admet-1885	38	43	hours	hour	NOUN
admet-1885	39	1	[	[	X
admet-1885	39	2	12	12	NUM
admet-1885	39	3	]	]	PUNCT
admet-1885	39	4	.	.	PUNCT
admet-1885	40	1	evidence	evidence	NOUN
admet-1885	40	2	shows	show	VERB
admet-1885	40	3	that	that	SCONJ
admet-1885	40	4	ap	ap	PROPN
admet-1885	40	5	is	be	AUX
admet-1885	40	6	a	a	DET
admet-1885	40	7	p	p	NOUN
admet-1885	40	8	-	-	PUNCT
admet-1885	40	9	gp	gp	NOUN
admet-1885	40	10	substrate	substrate	NOUN
admet-1885	40	11	and	and	CCONJ
admet-1885	40	12	its	its	PRON
admet-1885	40	13	efflux	efflux	NOUN
admet-1885	40	14	is	be	AUX
admet-1885	40	15	affected	affect	VERB
admet-1885	40	16	by	by	ADP
admet-1885	40	17	p	p	NOUN
admet-1885	40	18	-	-	PUNCT
admet-1885	40	19	gp	gp	NOUN
admet-1885	40	20	inhibitors	inhibitor	NOUN
admet-1885	40	21	,	,	PUNCT
admet-1885	40	22	like	like	ADP
admet-1885	40	23	ketoconazole	ketoconazole	NOUN
admet-1885	40	24	or	or	CCONJ
admet-1885	40	25	cyclosporin	cyclosporin	NOUN
admet-1885	40	26	on	on	ADP
admet-1885	40	27	the	the	DET
admet-1885	40	28	caco	caco	NOUN
admet-1885	40	29	-	-	PUNCT
admet-1885	40	30	cell	cell	NOUN
admet-1885	40	31	membrane	membrane	NOUN
admet-1885	41	1	[	[	X
admet-1885	41	2	13	13	NUM
admet-1885	41	3	]	]	PUNCT
admet-1885	41	4	.	.	PUNCT
admet-1885	42	1	ap	ap	PROPN
admet-1885	42	2	mainly	mainly	ADV
admet-1885	42	3	distributes	distribute	VERB
admet-1885	42	4	extracellular	extracellular	ADJ
admet-1885	42	5	fluids	fluid	NOUN
admet-1885	42	6	with	with	ADP
admet-1885	42	7	a	a	DET
admet-1885	42	8	volume	volume	NOUN
admet-1885	42	9	of	of	ADP
admet-1885	42	10	distribution	distribution	NOUN
admet-1885	42	11	of	of	ADP
admet-1885	42	12	21	21	NUM
admet-1885	42	13	l	l	NOUN
admet-1885	42	14	and	and	CCONJ
admet-1885	42	15	is	be	AUX
admet-1885	42	16	87	87	NUM
admet-1885	42	17	to	to	PART
admet-1885	42	18	90	90	NUM
admet-1885	42	19	%	%	NOUN
admet-1885	42	20	bound	bind	VERB
admet-1885	42	21	to	to	PART
admet-1885	42	22	plasma	plasma	NOUN
admet-1885	42	23	protein	protein	NOUN
admet-1885	42	24	,	,	PUNCT
admet-1885	42	25	mainly	mainly	ADV
admet-1885	42	26	albumin	albumin	ADJ
admet-1885	42	27	[	[	X
admet-1885	42	28	14	14	NUM
admet-1885	42	29	]	]	PUNCT
admet-1885	42	30	.	.	PUNCT
admet-1885	43	1	the	the	DET
admet-1885	43	2	half	half	ADJ
admet-1885	43	3	-	-	PUNCT
admet-1885	43	4	life	life	NOUN
admet-1885	43	5	of	of	ADP
admet-1885	43	6	ap	ap	PROPN
admet-1885	43	7	is	be	AUX
admet-1885	43	8	about	about	ADV
admet-1885	43	9	12	12	NUM
admet-1885	43	10	hours	hour	NOUN
admet-1885	44	1	[	[	X
admet-1885	44	2	15	15	NUM
admet-1885	44	3	]	]	PUNCT
admet-1885	44	4	and	and	CCONJ
admet-1885	44	5	the	the	DET
admet-1885	44	6	elimination	elimination	NOUN
admet-1885	44	7	of	of	ADP
admet-1885	44	8	ap	ap	PROPN
admet-1885	44	9	involves	involve	VERB
admet-1885	44	10	metabolism	metabolism	NOUN
admet-1885	44	11	,	,	PUNCT
admet-1885	44	12	biliary	biliary	NOUN
admet-1885	44	13	excretion	excretion	NOUN
admet-1885	44	14	,	,	PUNCT
admet-1885	44	15	and	and	CCONJ
admet-1885	44	16	renal	renal	ADJ
admet-1885	44	17	excretion	excretion	NOUN
admet-1885	44	18	of	of	ADP
admet-1885	44	19	unchanged	unchanged	ADJ
admet-1885	44	20	drug	drug	NOUN
admet-1885	44	21	.	.	PUNCT
admet-1885	45	1	the	the	DET
admet-1885	45	2	pathways	pathway	NOUN
admet-1885	45	3	of	of	ADP
admet-1885	45	4	metabolizing	metabolize	VERB
admet-1885	45	5	ap	ap	PROPN
admet-1885	45	6	include	include	VERB
admet-1885	45	7	o	o	NOUN
admet-1885	45	8	-	-	NOUN
admet-1885	45	9	demethylation	demethylation	NOUN
admet-1885	45	10	,	,	PUNCT
admet-1885	45	11	hydroxylation	hydroxylation	NOUN
admet-1885	45	12	,	,	PUNCT
admet-1885	45	13	and	and	CCONJ
admet-1885	45	14	sulfation	sulfation	NOUN
admet-1885	45	15	of	of	ADP
admet-1885	45	16	hydroxylated	hydroxylated	ADJ
admet-1885	45	17	o	o	PROPN
admet-1885	45	18	-	-	PROPN
admet-1885	45	19	demethyl	demethyl	PROPN
admet-1885	45	20	ap	ap	PROPN
admet-1885	45	21	with	with	ADP
admet-1885	45	22	a	a	DET
admet-1885	45	23	primary	primary	ADJ
admet-1885	45	24	metabolism	metabolism	NOUN
admet-1885	45	25	going	go	VERB
admet-1885	45	26	on	on	ADP
admet-1885	45	27	through	through	ADP
admet-1885	45	28	cytochrome	cytochrome	ADJ
admet-1885	45	29	p450	p450	PROPN
admet-1885	45	30	(	(	PUNCT
admet-1885	45	31	cyp	cyp	ADJ
admet-1885	45	32	)	)	PUNCT
admet-1885	45	33	3a4	3a4	NUM
admet-1885	45	34	,	,	PUNCT
admet-1885	45	35	with	with	ADP
admet-1885	45	36	slight	slight	ADJ
admet-1885	45	37	help	help	NOUN
admet-1885	45	38	from	from	ADP
admet-1885	45	39	cyp2c9	cyp2c9	NOUN
admet-1885	45	40	,	,	PUNCT
admet-1885	45	41	cyp2c19	cyp2c19	NOUN
admet-1885	45	42	,	,	PUNCT
admet-1885	45	43	cyp2c8	cyp2c8	ADV
admet-1885	45	44	,	,	PUNCT
admet-1885	45	45	and	and	CCONJ
admet-1885	45	46	cyp1a2	cyp1a2	ADJ
admet-1885	45	47	.	.	PUNCT
admet-1885	46	1	a	a	DET
admet-1885	46	2	similar	similar	ADJ
admet-1885	46	3	profile	profile	NOUN
admet-1885	46	4	was	be	AUX
admet-1885	46	5	noticed	notice	VERB
admet-1885	46	6	in	in	ADP
admet-1885	46	7	rats	rat	NOUN
admet-1885	46	8	in	in	ADP
admet-1885	46	9	the	the	DET
admet-1885	46	10	preclinical	preclinical	ADJ
admet-1885	46	11	study	study	NOUN
admet-1885	46	12	phase	phase	NOUN
admet-1885	46	13	;	;	PUNCT
admet-1885	46	14	the	the	DET
admet-1885	46	15	o	o	PROPN
admet-1885	46	16	-	-	PROPN
admet-1885	46	17	dimethyl	dimethyl	PROPN
admet-1885	46	18	ap	ap	PROPN
admet-1885	46	19	was	be	AUX
admet-1885	46	20	the	the	DET
admet-1885	46	21	major	major	ADJ
admet-1885	46	22	metabolite	metabolite	NOUN
admet-1885	46	23	[	[	X
admet-1885	46	24	16	16	NUM
admet-1885	46	25	]	]	PUNCT
admet-1885	46	26	.	.	PUNCT
admet-1885	47	1	admet	admet	PROPN
admet-1885	47	2	&	&	CCONJ
admet-1885	47	3	dmpk	dmpk	PROPN
admet-1885	47	4	11(4	11(4	NUM
admet-1885	47	5	)	)	PUNCT
admet-1885	47	6	(	(	PUNCT
admet-1885	47	7	2023	2023	NUM
admet-1885	47	8	)	)	PUNCT
admet-1885	47	9	533	533	NUM
admet-1885	47	10	-	-	SYM
admet-1885	47	11	550	550	NUM
admet-1885	47	12	enhancement	enhancement	NOUN
admet-1885	47	13	of	of	ADP
admet-1885	47	14	apixaban	apixaban	ADJ
admet-1885	47	15	solubility	solubility	NOUN
admet-1885	47	16	by	by	ADP
admet-1885	47	17	cyclodextrins	cyclodextrin	NOUN
admet-1885	47	18	doi	doi	PROPN
admet-1885	47	19	:	:	PUNCT
admet-1885	47	20	https://doi.org/10.5599/adme	https://doi.org/10.5599/adme	NOUN
admet-1885	47	21	t.1885	t.1885	ADP
admet-1885	47	22	535	535	NUM
admet-1885	47	23	cyclodextrins	cyclodextrin	NOUN
admet-1885	47	24	are	be	AUX
admet-1885	47	25	cyclic	cyclic	ADJ
admet-1885	47	26	oligomers	oligomer	NOUN
admet-1885	47	27	capable	capable	ADJ
admet-1885	47	28	of	of	ADP
admet-1885	47	29	producing	produce	VERB
admet-1885	47	30	water	water	NOUN
admet-1885	47	31	-	-	PUNCT
admet-1885	47	32	soluble	soluble	ADJ
admet-1885	47	33	inclusion	inclusion	NOUN
admet-1885	47	34	complexes	complex	NOUN
admet-1885	47	35	with	with	ADP
admet-1885	47	36	small	small	ADJ
admet-1885	47	37	molecules	molecule	NOUN
admet-1885	47	38	and	and	CCONJ
admet-1885	47	39	portions	portion	NOUN
admet-1885	47	40	of	of	ADP
admet-1885	47	41	large	large	ADJ
admet-1885	47	42	compounds	compound	NOUN
admet-1885	47	43	.	.	PUNCT
admet-1885	48	1	these	these	DET
admet-1885	48	2	biocompatible	biocompatible	ADJ
admet-1885	48	3	,	,	PUNCT
admet-1885	48	4	cyclic	cyclic	ADJ
admet-1885	48	5	oligosaccharides	oligosaccharide	NOUN
admet-1885	48	6	will	will	AUX
admet-1885	48	7	not	not	PART
admet-1885	48	8	cause	cause	VERB
admet-1885	48	9	an	an	DET
admet-1885	48	10	immune	immune	ADJ
admet-1885	48	11	reaction	reaction	NOUN
admet-1885	48	12	and	and	CCONJ
admet-1885	48	13	have	have	VERB
admet-1885	48	14	little	little	ADJ
admet-1885	48	15	toxicity	toxicity	NOUN
admet-1885	48	16	in	in	ADP
admet-1885	48	17	animals	animal	NOUN
admet-1885	48	18	and	and	CCONJ
admet-1885	48	19	humans	human	NOUN
admet-1885	48	20	.	.	PUNCT
admet-1885	49	1	cyclodextrins	cyclodextrin	NOUN
admet-1885	49	2	have	have	VERB
admet-1885	49	3	multiple	multiple	ADJ
admet-1885	49	4	purposes	purpose	NOUN
admet-1885	49	5	in	in	ADP
admet-1885	49	6	the	the	DET
admet-1885	49	7	pharmaceutical	pharmaceutical	ADJ
admet-1885	49	8	industry	industry	NOUN
admet-1885	49	9	,	,	PUNCT
admet-1885	49	10	including	include	VERB
admet-1885	49	11	increasing	increase	VERB
admet-1885	49	12	the	the	DET
admet-1885	49	13	bioavailability	bioavailability	NOUN
admet-1885	49	14	of	of	ADP
admet-1885	49	15	drugs	drug	NOUN
admet-1885	49	16	.	.	PUNCT
admet-1885	50	1	cyclodextrin	cyclodextrin	NOUN
admet-1885	50	2	-	-	PUNCT
admet-1885	50	3	containing	contain	VERB
admet-1885	50	4	polymers	polymer	NOUN
admet-1885	50	5	are	be	AUX
admet-1885	50	6	studied	study	VERB
admet-1885	50	7	and	and	CCONJ
admet-1885	50	8	their	their	PRON
admet-1885	50	9	use	use	NOUN
admet-1885	50	10	in	in	ADP
admet-1885	50	11	drug	drug	NOUN
admet-1885	50	12	delivery	delivery	NOUN
admet-1885	50	13	presented	present	VERB
admet-1885	50	14	an	an	DET
admet-1885	50	15	interest	interest	NOUN
admet-1885	50	16	in	in	ADP
admet-1885	50	17	the	the	DET
admet-1885	50	18	use	use	NOUN
admet-1885	50	19	of	of	ADP
admet-1885	50	20	cyclodextrin	cyclodextrin	NOUN
admet-1885	50	21	-	-	PUNCT
admet-1885	50	22	containing	contain	VERB
admet-1885	50	23	polymers	polymer	NOUN
admet-1885	50	24	to	to	PART
admet-1885	50	25	provide	provide	VERB
admet-1885	50	26	a	a	DET
admet-1885	50	27	better	well	ADJ
admet-1885	50	28	ability	ability	NOUN
admet-1885	50	29	in	in	ADP
admet-1885	50	30	the	the	DET
admet-1885	50	31	delivery	delivery	NOUN
admet-1885	50	32	of	of	ADP
admet-1885	50	33	nucleic	nucleic	ADJ
admet-1885	50	34	acids	acid	NOUN
admet-1885	51	1	[	[	X
admet-1885	51	2	17	17	NUM
admet-1885	51	3	]	]	PUNCT
admet-1885	51	4	.	.	PUNCT
admet-1885	52	1	the	the	DET
admet-1885	52	2	aim	aim	NOUN
admet-1885	52	3	of	of	ADP
admet-1885	52	4	this	this	DET
admet-1885	52	5	study	study	NOUN
admet-1885	52	6	is	be	AUX
admet-1885	52	7	to	to	PART
admet-1885	52	8	prepare	prepare	VERB
admet-1885	52	9	and	and	CCONJ
admet-1885	52	10	evaluate	evaluate	VERB
admet-1885	52	11	βcd	βcd	NOUN
admet-1885	52	12	-	-	PUNCT
admet-1885	52	13	ap	ap	NOUN
admet-1885	52	14	and	and	CCONJ
admet-1885	52	15	hpβcd	hpβcd	PROPN
admet-1885	52	16	-	-	PUNCT
admet-1885	52	17	ap	ap	PROPN
admet-1885	52	18	inclusion	inclusion	NOUN
admet-1885	52	19	complexes	complexe	VERB
admet-1885	52	20	to	to	PART
admet-1885	52	21	improve	improve	VERB
admet-1885	52	22	the	the	DET
admet-1885	52	23	solubility	solubility	NOUN
admet-1885	52	24	and	and	CCONJ
admet-1885	52	25	dissolution	dissolution	NOUN
admet-1885	52	26	rate	rate	NOUN
admet-1885	52	27	of	of	ADP
admet-1885	52	28	an	an	DET
admet-1885	52	29	oral	oral	ADJ
admet-1885	52	30	dosage	dosage	NOUN
admet-1885	52	31	form	form	NOUN
admet-1885	52	32	of	of	ADP
admet-1885	52	33	ap	ap	PROPN
admet-1885	52	34	.	.	PUNCT
admet-1885	53	1	experimental	experimental	ADJ
admet-1885	53	2	chemicals	chemical	NOUN
admet-1885	53	3	and	and	CCONJ
admet-1885	53	4	instrumentation	instrumentation	NOUN
admet-1885	53	5	apixaban	apixaban	NOUN
admet-1885	53	6	(	(	PUNCT
admet-1885	53	7	purity	purity	NOUN
admet-1885	53	8	99.5	99.5	NUM
admet-1885	53	9	/sigma	/sigma	NUM
admet-1885	53	10	)	)	PUNCT
admet-1885	53	11	,	,	PUNCT
admet-1885	53	12	βcd	βcd	NUM
admet-1885	53	13	and	and	CCONJ
admet-1885	53	14	hpβcd	hpβcd	ADJ
admet-1885	53	15	/sigma	/sigma	PUNCT
admet-1885	53	16	)	)	PUNCT
admet-1885	53	17	a	a	DET
admet-1885	53	18	hitachi	hitachi	PROPN
admet-1885	53	19	ratio	ratio	PROPN
admet-1885	53	20	beam	beam	PROPN
admet-1885	53	21	u-1800	u-1800	PROPN
admet-1885	53	22	spectrometer	spectrometer	NOUN
admet-1885	53	23	,	,	PUNCT
admet-1885	53	24	evisa	evisa	NOUN
admet-1885	53	25	,	,	PUNCT
admet-1885	53	26	ependorff	ependorff	VERB
admet-1885	53	27	5810	5810	NUM
admet-1885	53	28	centrifuge	centrifuge	NOUN
admet-1885	53	29	with	with	ADP
admet-1885	53	30	a	a	DET
admet-1885	53	31	maximum	maximum	ADJ
admet-1885	53	32	rpm	rpm	NOUN
admet-1885	53	33	of	of	ADP
admet-1885	53	34	11,000	11,000	NUM
admet-1885	53	35	(	(	PUNCT
admet-1885	53	36	ny	ny	PROPN
admet-1885	53	37	,	,	PUNCT
admet-1885	53	38	usa	usa	PROPN
admet-1885	53	39	)	)	PUNCT
admet-1885	53	40	,	,	PUNCT
admet-1885	53	41	vortex	vortex	NOUN
admet-1885	53	42	mixer	mixer	NOUN
admet-1885	53	43	(	(	PUNCT
admet-1885	53	44	labinco	labinco	PROPN
admet-1885	53	45	l46	l46	PROPN
admet-1885	53	46	,	,	PUNCT
admet-1885	53	47	netherland	netherland	PROPN
admet-1885	53	48	)	)	PUNCT
admet-1885	53	49	,	,	PUNCT
admet-1885	53	50	eppendorf	eppendorf	PROPN
admet-1885	53	51	centrifuge	centrifuge	VERB
admet-1885	53	52	5810	5810	NUM
admet-1885	53	53	r	r	NOUN
admet-1885	53	54	,	,	PUNCT
admet-1885	53	55	balance	balance	NOUN
admet-1885	53	56	mettler	mettler	X
admet-1885	53	57	96	96	NUM
admet-1885	53	58	(	(	PUNCT
admet-1885	53	59	at300	at300	ADJ
admet-1885	53	60	,	,	PUNCT
admet-1885	53	61	sartorius	sartorius	NOUN
admet-1885	53	62	,	,	PUNCT
admet-1885	53	63	five	five	NUM
admet-1885	53	64	decimals	decimal	NOUN
admet-1885	53	65	)	)	PUNCT
admet-1885	53	66	,	,	PUNCT
admet-1885	53	67	ph	ph	ADJ
admet-1885	53	68	meter	meter	NOUN
admet-1885	53	69	(	(	PUNCT
admet-1885	53	70	sartorius	sartorius	NOUN
admet-1885	53	71	7110	7110	NUM
admet-1885	53	72	)	)	PUNCT
admet-1885	53	73	,	,	PUNCT
admet-1885	53	74	sonicator	sonicator	NOUN
admet-1885	53	75	(	(	PUNCT
admet-1885	53	76	elmasonic	elmasonic	ADJ
admet-1885	53	77	s100	s100	PROPN
admet-1885	53	78	)	)	PUNCT
admet-1885	53	79	,	,	PUNCT
admet-1885	53	80	water	water	NOUN
admet-1885	53	81	bath	bath	NOUN
admet-1885	53	82	bm100	bm100	NOUN
admet-1885	53	83	with	with	ADP
admet-1885	53	84	digital	digital	ADJ
admet-1885	53	85	thermostat	thermostat	NOUN
admet-1885	53	86	,	,	PUNCT
admet-1885	53	87	ir	ir	ADJ
admet-1885	53	88	-	-	ADJ
admet-1885	53	89	prestige-21	prestige-21	PROPN
admet-1885	53	90	ftir	ftir	PROPN
admet-1885	53	91	spectrometer	spectrometer	NOUN
admet-1885	53	92	(	(	PUNCT
admet-1885	53	93	shimadzu	shimadzu	PROPN
admet-1885	53	94	,	,	PUNCT
admet-1885	53	95	japan	japan	PROPN
admet-1885	53	96	)	)	PUNCT
admet-1885	53	97	,	,	PUNCT
admet-1885	53	98	buchi	buchi	PROPN
admet-1885	53	99	nano	nano	PROPN
admet-1885	53	100	spray	spray	VERB
admet-1885	53	101	dryer	dryer	NOUN
admet-1885	53	102	b-90	b-90	PROPN
admet-1885	53	103	hp	hp	NOUN
admet-1885	53	104	were	be	AUX
admet-1885	53	105	used	use	VERB
admet-1885	53	106	throughout	throughout	ADP
admet-1885	53	107	the	the	DET
admet-1885	53	108	study	study	NOUN
admet-1885	53	109	.	.	PUNCT
admet-1885	54	1	development	development	NOUN
admet-1885	54	2	of	of	ADP
admet-1885	54	3	analytical	analytical	ADJ
admet-1885	54	4	method	method	NOUN
admet-1885	54	5	based	base	VERB
admet-1885	54	6	on	on	ADP
admet-1885	54	7	uv	uv	NOUN
admet-1885	54	8	absorbance	absorbance	NOUN
admet-1885	54	9	ap	ap	PROPN
admet-1885	54	10	is	be	AUX
admet-1885	54	11	slightly	slightly	ADV
admet-1885	54	12	soluble	soluble	ADJ
admet-1885	54	13	in	in	ADP
admet-1885	54	14	water	water	NOUN
admet-1885	54	15	.	.	PUNCT
admet-1885	55	1	absolute	absolute	ADJ
admet-1885	55	2	ethanol	ethanol	NOUN
admet-1885	55	3	and	and	CCONJ
admet-1885	55	4	methanol	methanol	NOUN
admet-1885	55	5	were	be	AUX
admet-1885	55	6	tried	try	VERB
admet-1885	55	7	in	in	ADP
admet-1885	55	8	this	this	DET
admet-1885	55	9	study	study	NOUN
admet-1885	55	10	to	to	PART
admet-1885	55	11	prepare	prepare	VERB
admet-1885	55	12	ap	ap	PROPN
admet-1885	55	13	stock	stock	NOUN
admet-1885	55	14	solution	solution	NOUN
admet-1885	55	15	.	.	PUNCT
admet-1885	56	1	the	the	DET
admet-1885	56	2	best	good	ADJ
admet-1885	56	3	solubility	solubility	NOUN
admet-1885	56	4	was	be	AUX
admet-1885	56	5	obtained	obtain	VERB
admet-1885	56	6	in	in	ADP
admet-1885	56	7	methanol	methanol	NOUN
admet-1885	56	8	(	(	PUNCT
admet-1885	56	9	1	1	NUM
admet-1885	56	10	mg	mg	NUM
admet-1885	56	11	/	/	SYM
admet-1885	56	12	ml	ml	NOUN
admet-1885	56	13	)	)	PUNCT
admet-1885	56	14	.	.	PUNCT
admet-1885	57	1	good	good	ADJ
admet-1885	57	2	solubility	solubility	NOUN
admet-1885	57	3	was	be	AUX
admet-1885	57	4	also	also	ADV
admet-1885	57	5	obtained	obtain	VERB
admet-1885	57	6	from	from	ADP
admet-1885	57	7	ethanol	ethanol	NOUN
admet-1885	57	8	(	(	PUNCT
admet-1885	57	9	0.88	0.88	NUM
admet-1885	57	10	mg	mg	PROPN
admet-1885	57	11	/	/	SYM
admet-1885	57	12	ml	ml	NOUN
admet-1885	57	13	)	)	PUNCT
admet-1885	57	14	that	that	PRON
admet-1885	57	15	covered	cover	VERB
admet-1885	57	16	the	the	DET
admet-1885	57	17	required	require	VERB
admet-1885	57	18	and	and	CCONJ
admet-1885	57	19	expected	expected	ADJ
admet-1885	57	20	concentrations	concentration	NOUN
admet-1885	57	21	.	.	PUNCT
admet-1885	58	1	due	due	ADP
admet-1885	58	2	to	to	ADP
admet-1885	58	3	methanol	methanol	NOUN
admet-1885	58	4	toxicity	toxicity	NOUN
admet-1885	58	5	and	and	CCONJ
admet-1885	58	6	methanol	methanol	NOUN
admet-1885	58	7	residue	residue	NOUN
admet-1885	58	8	avoidance	avoidance	NOUN
admet-1885	58	9	,	,	PUNCT
admet-1885	58	10	ethanol	ethanol	NOUN
admet-1885	58	11	was	be	AUX
admet-1885	58	12	chosen	choose	VERB
admet-1885	58	13	as	as	ADP
admet-1885	58	14	a	a	DET
admet-1885	58	15	solvent	solvent	NOUN
admet-1885	58	16	in	in	ADP
admet-1885	58	17	addition	addition	NOUN
admet-1885	58	18	to	to	ADP
admet-1885	58	19	ethanol	ethanol	NOUN
admet-1885	58	20	–	–	PUNCT
admet-1885	58	21	water	water	NOUN
admet-1885	58	22	mixture	mixture	NOUN
admet-1885	58	23	for	for	ADP
admet-1885	58	24	more	more	ADJ
admet-1885	58	25	dilute	dilute	ADJ
admet-1885	58	26	samples	sample	NOUN
admet-1885	58	27	.	.	PUNCT
admet-1885	59	1	the	the	DET
admet-1885	59	2	stock	stock	NOUN
admet-1885	59	3	solution	solution	NOUN
admet-1885	59	4	of	of	ADP
admet-1885	59	5	ap	ap	PROPN
admet-1885	59	6	in	in	ADP
admet-1885	59	7	ethanol	ethanol	NOUN
admet-1885	59	8	was	be	AUX
admet-1885	59	9	prepared	prepare	VERB
admet-1885	59	10	by	by	ADP
admet-1885	59	11	dissolving	dissolve	VERB
admet-1885	59	12	25	25	NUM
admet-1885	59	13	mg	mg	NUM
admet-1885	59	14	ap	ap	PROPN
admet-1885	59	15	in	in	ADP
admet-1885	59	16	50	50	NUM
admet-1885	59	17	ml	ml	NOUN
admet-1885	59	18	ethanol	ethanol	NOUN
admet-1885	59	19	with	with	ADP
admet-1885	59	20	gentle	gentle	ADJ
admet-1885	59	21	stirring	stirring	NOUN
admet-1885	59	22	and	and	CCONJ
admet-1885	59	23	then	then	ADV
admet-1885	59	24	filtration	filtration	NOUN
admet-1885	59	25	to	to	PART
admet-1885	59	26	get	get	VERB
admet-1885	59	27	a	a	DET
admet-1885	59	28	clear	clear	ADJ
admet-1885	59	29	solution	solution	NOUN
admet-1885	59	30	.	.	PUNCT
admet-1885	60	1	dilution	dilution	NOUN
admet-1885	60	2	to	to	ADP
admet-1885	60	3	50	50	NUM
admet-1885	60	4	and	and	CCONJ
admet-1885	60	5	100	100	NUM
admet-1885	60	6	µg	µg	ADV
admet-1885	60	7	/	/	SYM
admet-1885	60	8	ml	ml	NOUN
admet-1885	60	9	were	be	AUX
admet-1885	60	10	prepared	prepare	VERB
admet-1885	60	11	using	use	VERB
admet-1885	60	12	ethanol	ethanol	NOUN
admet-1885	60	13	and	and	CCONJ
admet-1885	60	14	scanned	scan	VERB
admet-1885	60	15	from	from	ADP
admet-1885	60	16	200	200	NUM
admet-1885	60	17	400	400	NUM
admet-1885	60	18	nm	nm	NOUN
admet-1885	60	19	in	in	ADP
admet-1885	60	20	uv	uv	NOUN
admet-1885	60	21	spectrophotometer	spectrophotometer	NOUN
admet-1885	60	22	(	(	PUNCT
admet-1885	60	23	model	model	NOUN
admet-1885	60	24	u-2000	u-2000	PROPN
admet-1885	60	25	,	,	PUNCT
admet-1885	60	26	hitachi	hitachi	PROPN
admet-1885	60	27	,	,	PUNCT
admet-1885	60	28	tokyo	tokyo	PROPN
admet-1885	60	29	,	,	PUNCT
admet-1885	60	30	japan	japan	PROPN
admet-1885	60	31	)	)	PUNCT
admet-1885	60	32	.	.	PUNCT
admet-1885	61	1	quartz	quartz	PROPN
admet-1885	61	2	cuvette	cuvette	PROPN
admet-1885	61	3	was	be	AUX
admet-1885	61	4	used	use	VERB
admet-1885	61	5	and	and	CCONJ
admet-1885	61	6	ethanol	ethanol	NOUN
admet-1885	61	7	as	as	ADV
admet-1885	61	8	blank	blank	ADJ
admet-1885	61	9	and	and	CCONJ
admet-1885	61	10	control	control	NOUN
admet-1885	61	11	.	.	PUNCT
admet-1885	62	1	βcd	βcd	VERB
admet-1885	62	2	and	and	CCONJ
admet-1885	62	3	hpβcd	hpβcd	ADJ
admet-1885	62	4	soluble	soluble	ADJ
admet-1885	62	5	in	in	ADP
admet-1885	62	6	distilled	distil	VERB
admet-1885	62	7	water	water	NOUN
admet-1885	62	8	were	be	AUX
admet-1885	62	9	also	also	ADV
admet-1885	62	10	scanned	scan	VERB
admet-1885	62	11	between	between	ADP
admet-1885	62	12	200	200	NUM
admet-1885	62	13	-	-	SYM
admet-1885	62	14	400	400	NUM
admet-1885	62	15	nm	nm	NOUN
admet-1885	62	16	to	to	PART
admet-1885	62	17	ensure	ensure	VERB
admet-1885	62	18	the	the	DET
admet-1885	62	19	specificity	specificity	NOUN
admet-1885	62	20	of	of	ADP
admet-1885	62	21	the	the	DET
admet-1885	62	22	method	method	NOUN
admet-1885	62	23	when	when	SCONJ
admet-1885	62	24	used	use	VERB
admet-1885	62	25	to	to	PART
admet-1885	62	26	measure	measure	VERB
admet-1885	62	27	ap	ap	PROPN
admet-1885	62	28	in	in	ADP
admet-1885	62	29	the	the	DET
admet-1885	62	30	prepared	prepared	ADJ
admet-1885	62	31	complexes	complex	NOUN
admet-1885	62	32	.	.	PUNCT
admet-1885	63	1	method	method	NOUN
admet-1885	63	2	validation	validation	NOUN
admet-1885	63	3	different	different	ADJ
admet-1885	63	4	dilutions	dilution	NOUN
admet-1885	63	5	of	of	ADP
admet-1885	63	6	ap	ap	PROPN
admet-1885	63	7	were	be	AUX
admet-1885	63	8	made	make	VERB
admet-1885	63	9	from	from	ADP
admet-1885	63	10	the	the	DET
admet-1885	63	11	stock	stock	NOUN
admet-1885	63	12	solution	solution	NOUN
admet-1885	63	13	in	in	ADP
admet-1885	63	14	ethanol	ethanol	NOUN
admet-1885	63	15	and	and	CCONJ
admet-1885	63	16	used	use	VERB
admet-1885	63	17	in	in	ADP
admet-1885	63	18	different	different	ADJ
admet-1885	63	19	tests	test	NOUN
admet-1885	63	20	of	of	ADP
admet-1885	63	21	validation	validation	NOUN
admet-1885	63	22	according	accord	VERB
admet-1885	63	23	to	to	ADP
admet-1885	63	24	the	the	DET
admet-1885	63	25	ich	ich	NOUN
admet-1885	63	26	guideline	guideline	NOUN
admet-1885	63	27	of	of	ADP
admet-1885	63	28	pharmaceutical	pharmaceutical	ADJ
admet-1885	63	29	analysis	analysis	NOUN
admet-1885	63	30	.	.	PUNCT
admet-1885	64	1	linearity	linearity	NOUN
admet-1885	64	2	,	,	PUNCT
admet-1885	64	3	precision	precision	NOUN
admet-1885	64	4	and	and	CCONJ
admet-1885	64	5	accuracy	accuracy	NOUN
admet-1885	64	6	,	,	PUNCT
admet-1885	64	7	recovery	recovery	NOUN
admet-1885	64	8	and	and	CCONJ
admet-1885	64	9	robustness	robustness	NOUN
admet-1885	64	10	were	be	AUX
admet-1885	64	11	performed	perform	VERB
admet-1885	64	12	to	to	PART
admet-1885	64	13	validate	validate	VERB
admet-1885	64	14	the	the	DET
admet-1885	64	15	developed	develop	VERB
admet-1885	64	16	method	method	NOUN
admet-1885	64	17	.	.	PUNCT
admet-1885	65	1	calibration	calibration	NOUN
admet-1885	65	2	concentrations	concentration	NOUN
admet-1885	65	3	used	use	VERB
admet-1885	65	4	in	in	ADP
admet-1885	65	5	the	the	DET
admet-1885	65	6	linearity	linearity	NOUN
admet-1885	65	7	test	test	NOUN
admet-1885	65	8	were	be	AUX
admet-1885	65	9	15	15	NUM
admet-1885	65	10	,	,	PUNCT
admet-1885	65	11	25	25	NUM
admet-1885	65	12	,	,	PUNCT
admet-1885	65	13	30	30	NUM
admet-1885	65	14	,	,	PUNCT
admet-1885	65	15	50	50	NUM
admet-1885	65	16	,	,	PUNCT
admet-1885	65	17	60	60	NUM
admet-1885	65	18	,	,	PUNCT
admet-1885	65	19	70	70	NUM
admet-1885	65	20	,	,	PUNCT
admet-1885	65	21	80	80	NUM
admet-1885	65	22	and	and	CCONJ
admet-1885	65	23	90	90	NUM
admet-1885	65	24	µg	µg	NOUN
admet-1885	65	25	/	/	SYM
admet-1885	65	26	ml	ml	NOUN
admet-1885	65	27	.	.	PUNCT
admet-1885	66	1	although	although	SCONJ
admet-1885	66	2	5	5	NUM
admet-1885	66	3	µg	µg	ADV
admet-1885	66	4	/	/	SYM
admet-1885	66	5	ml	ml	NOUN
admet-1885	66	6	was	be	AUX
admet-1885	66	7	also	also	ADV
admet-1885	66	8	tested	test	VERB
admet-1885	66	9	for	for	ADP
admet-1885	66	10	linearity	linearity	NOUN
admet-1885	66	11	as	as	ADP
admet-1885	66	12	a	a	DET
admet-1885	66	13	lower	low	ADJ
admet-1885	66	14	limit	limit	NOUN
admet-1885	66	15	of	of	ADP
admet-1885	66	16	quantification	quantification	NOUN
admet-1885	66	17	.	.	PUNCT
admet-1885	67	1	absorbance	absorbance	NOUN
admet-1885	67	2	was	be	AUX
admet-1885	67	3	read	read	VERB
admet-1885	67	4	trice	trice	NOUN
admet-1885	67	5	and	and	CCONJ
admet-1885	67	6	average	average	ADJ
admet-1885	67	7	±	±	NOUN
admet-1885	67	8	sd	sd	NOUN
admet-1885	67	9	was	be	AUX
admet-1885	67	10	recorded	record	VERB
admet-1885	67	11	at	at	ADP
admet-1885	67	12	278	278	NUM
admet-1885	67	13	nm	nm	NOUN
admet-1885	67	14	.	.	PUNCT
admet-1885	68	1	inter	inter	PROPN
admet-1885	68	2	and	and	CCONJ
admet-1885	68	3	intra	intra	ADJ
admet-1885	68	4	-	-	ADJ
admet-1885	68	5	day	day	ADJ
admet-1885	68	6	precision	precision	NOUN
admet-1885	68	7	of	of	ADP
admet-1885	68	8	the	the	DET
admet-1885	68	9	study	study	NOUN
admet-1885	68	10	were	be	AUX
admet-1885	68	11	examined	examine	VERB
admet-1885	68	12	and	and	CCONJ
admet-1885	68	13	established	establish	VERB
admet-1885	68	14	by	by	ADP
admet-1885	68	15	analysis	analysis	NOUN
admet-1885	68	16	of	of	ADP
admet-1885	68	17	6	6	NUM
admet-1885	68	18	samples	sample	NOUN
admet-1885	68	19	(	(	PUNCT
admet-1885	68	20	calibration	calibration	NOUN
admet-1885	68	21	concentrations	concentration	NOUN
admet-1885	68	22	)	)	PUNCT
admet-1885	68	23	with	with	ADP
admet-1885	68	24	three	three	NUM
admet-1885	68	25	replicates	replicate	NOUN
admet-1885	68	26	.	.	PUNCT
admet-1885	69	1	within	within	ADP
admet-1885	69	2	-	-	PUNCT
admet-1885	69	3	run	run	NOUN
admet-1885	69	4	accuracy	accuracy	NOUN
admet-1885	69	5	and	and	CCONJ
admet-1885	69	6	precision	precision	NOUN
admet-1885	69	7	of	of	ADP
admet-1885	69	8	the	the	DET
admet-1885	69	9	method	method	NOUN
admet-1885	69	10	were	be	AUX
admet-1885	69	11	calculated	calculate	VERB
admet-1885	69	12	by	by	ADP
admet-1885	69	13	analyzing	analyze	VERB
admet-1885	69	14	six	six	NUM
admet-1885	69	15	samples	sample	NOUN
admet-1885	69	16	with	with	ADP
admet-1885	69	17	three	three	NUM
admet-1885	69	18	replicates	replicate	NOUN
admet-1885	69	19	.	.	PUNCT
admet-1885	70	1	relative	relative	ADJ
admet-1885	70	2	standard	standard	ADJ
admet-1885	70	3	deviation	deviation	NOUN
admet-1885	70	4	(	(	PUNCT
admet-1885	70	5	rsd	rsd	NOUN
admet-1885	70	6	)	)	PUNCT
admet-1885	70	7	was	be	AUX
admet-1885	70	8	measured	measure	VERB
admet-1885	70	9	using	use	VERB
admet-1885	70	10	the	the	DET
admet-1885	70	11	proportions	proportion	NOUN
admet-1885	70	12	of	of	ADP
admet-1885	70	13	the	the	DET
admet-1885	70	14	standard	standard	ADJ
admet-1885	70	15	deviation	deviation	NOUN
admet-1885	70	16	to	to	ADP
admet-1885	70	17	the	the	DET
admet-1885	70	18	average	average	NOUN
admet-1885	70	19	.	.	PUNCT
admet-1885	71	1	the	the	DET
admet-1885	71	2	comparison	comparison	NOUN
admet-1885	71	3	of	of	ADP
admet-1885	71	4	practical	practical	ADJ
admet-1885	71	5	amounts	amount	NOUN
admet-1885	71	6	from	from	ADP
admet-1885	71	7	the	the	DET
admet-1885	71	8	controls	control	NOUN
admet-1885	71	9	with	with	ADP
admet-1885	71	10	actual	actual	ADJ
admet-1885	71	11	values	value	NOUN
admet-1885	71	12	present	present	ADJ
admet-1885	71	13	in	in	ADP
admet-1885	71	14	the	the	DET
admet-1885	71	15	samples	sample	NOUN
admet-1885	71	16	provides	provide	VERB
admet-1885	71	17	the	the	DET
admet-1885	71	18	accuracy	accuracy	NOUN
admet-1885	71	19	of	of	ADP
admet-1885	71	20	this	this	DET
admet-1885	71	21	method	method	NOUN
admet-1885	71	22	.	.	PUNCT
admet-1885	72	1	recovery	recovery	NOUN
admet-1885	72	2	is	be	AUX
admet-1885	72	3	a	a	DET
admet-1885	72	4	ratio	ratio	NOUN
admet-1885	72	5	of	of	ADP
admet-1885	72	6	the	the	DET
admet-1885	72	7	concentration	concentration	NOUN
admet-1885	72	8	of	of	ADP
admet-1885	72	9	analyte	analyte	NOUN
admet-1885	72	10	available	available	ADJ
admet-1885	72	11	in	in	ADP
admet-1885	72	12	or	or	CCONJ
admet-1885	72	13	mixed	mix	VERB
admet-1885	72	14	with	with	ADP
admet-1885	72	15	the	the	DET
admet-1885	72	16	analytical	analytical	ADJ
admet-1885	72	17	part	part	NOUN
admet-1885	72	18	of	of	ADP
admet-1885	72	19	the	the	DET
admet-1885	72	20	test	test	NOUN
admet-1885	72	21	substance	substance	NOUN
admet-1885	72	22	.	.	PUNCT
admet-1885	73	1	this	this	PRON
admet-1885	73	2	would	would	AUX
admet-1885	73	3	be	be	AUX
admet-1885	73	4	extracted	extract	VERB
admet-1885	73	5	and	and	CCONJ
admet-1885	73	6	submitted	submit	VERB
admet-1885	73	7	for	for	ADP
admet-1885	73	8	measurement	measurement	NOUN
admet-1885	73	9	(	(	PUNCT
admet-1885	73	10	ich	ich	NOUN
admet-1885	73	11	guidelines	guideline	NOUN
admet-1885	73	12	)	)	PUNCT
admet-1885	73	13	.	.	PUNCT
admet-1885	74	1	the	the	DET
admet-1885	74	2	test	test	NOUN
admet-1885	74	3	powder	powder	NOUN
admet-1885	74	4	and	and	CCONJ
admet-1885	74	5	https://doi.org/10.5599/admet.1885	https://doi.org/10.5599/admet.1885	NOUN
admet-1885	74	6	z.	z.	PROPN
admet-1885	74	7	n.	n.	PROPN
admet-1885	74	8	salman	salman	PROPN
admet-1885	74	9	et	et	PROPN
admet-1885	74	10	al	al	PROPN
admet-1885	74	11	.	.	PROPN
admet-1885	74	12	admet	admet	PROPN
admet-1885	74	13	&	&	CCONJ
admet-1885	74	14	dmpk	dmpk	PROPN
admet-1885	74	15	11(4	11(4	NUM
admet-1885	74	16	)	)	PUNCT
admet-1885	74	17	(	(	PUNCT
admet-1885	74	18	2023	2023	NUM
admet-1885	74	19	)	)	PUNCT
admet-1885	74	20	533	533	NUM
admet-1885	74	21	-	-	SYM
admet-1885	74	22	550	550	NUM
admet-1885	74	23	536	536	NUM
admet-1885	74	24	capsule	capsule	NOUN
admet-1885	74	25	were	be	AUX
admet-1885	74	26	used	use	VERB
admet-1885	74	27	to	to	PART
admet-1885	74	28	test	test	VERB
admet-1885	74	29	the	the	DET
admet-1885	74	30	recovery	recovery	NOUN
admet-1885	74	31	of	of	ADP
admet-1885	74	32	the	the	DET
admet-1885	74	33	method	method	NOUN
admet-1885	74	34	.	.	PUNCT
admet-1885	75	1	the	the	DET
admet-1885	75	2	formula	formula	NOUN
admet-1885	75	3	contained	contain	VERB
admet-1885	75	4	ap	ap	PROPN
admet-1885	75	5	beside	beside	ADP
admet-1885	75	6	other	other	ADJ
admet-1885	75	7	excipients	excipient	NOUN
admet-1885	75	8	prepared	prepare	VERB
admet-1885	75	9	to	to	PART
admet-1885	75	10	compare	compare	VERB
admet-1885	75	11	the	the	DET
admet-1885	75	12	dissolution	dissolution	NOUN
admet-1885	75	13	rate	rate	NOUN
admet-1885	75	14	of	of	ADP
admet-1885	75	15	the	the	DET
admet-1885	75	16	capsule	capsule	NOUN
admet-1885	75	17	containing	contain	VERB
admet-1885	75	18	the	the	DET
admet-1885	75	19	complex	complex	NOUN
admet-1885	75	20	to	to	ADP
admet-1885	75	21	the	the	DET
admet-1885	75	22	mixture	mixture	NOUN
admet-1885	75	23	of	of	ADP
admet-1885	75	24	drug	drug	NOUN
admet-1885	75	25	and	and	CCONJ
admet-1885	75	26	excipients	excipient	NOUN
admet-1885	75	27	.	.	PUNCT
admet-1885	76	1	one	one	NUM
admet-1885	76	2	capsule	capsule	NOUN
admet-1885	76	3	contains	contain	VERB
admet-1885	76	4	5	5	NUM
admet-1885	76	5	mg	mg	PROPN
admet-1885	76	6	ap	ap	PROPN
admet-1885	76	7	with	with	ADP
admet-1885	76	8	the	the	DET
admet-1885	76	9	powder	powder	NOUN
admet-1885	76	10	mix	mix	NOUN
admet-1885	76	11	.	.	PUNCT
admet-1885	77	1	a	a	DET
admet-1885	77	2	powder	powder	NOUN
admet-1885	77	3	weight	weight	NOUN
admet-1885	77	4	containing	contain	VERB
admet-1885	77	5	1	1	NUM
admet-1885	77	6	mg	mg	NOUN
admet-1885	77	7	ap	ap	PROPN
admet-1885	77	8	in	in	ADP
admet-1885	77	9	a	a	DET
admet-1885	77	10	powder	powder	NOUN
admet-1885	77	11	blend	blend	NOUN
admet-1885	77	12	was	be	AUX
admet-1885	77	13	taken	take	VERB
admet-1885	77	14	and	and	CCONJ
admet-1885	77	15	dissolved	dissolve	VERB
admet-1885	77	16	in	in	ADP
admet-1885	77	17	5	5	NUM
admet-1885	77	18	ml	ml	NOUN
admet-1885	77	19	ethanol	ethanol	NOUN
admet-1885	77	20	,	,	PUNCT
admet-1885	77	21	filtered	filter	VERB
admet-1885	77	22	through	through	ADP
admet-1885	77	23	membrane	membrane	NOUN
admet-1885	77	24	filter	filter	NOUN
admet-1885	77	25	0.45	0.45	NUM
admet-1885	77	26	and	and	CCONJ
admet-1885	77	27	2	2	NUM
admet-1885	77	28	ml	ml	NOUN
admet-1885	77	29	was	be	AUX
admet-1885	77	30	diluted	dilute	VERB
admet-1885	77	31	with	with	ADP
admet-1885	77	32	ethanol	ethanol	NOUN
admet-1885	77	33	to	to	ADP
admet-1885	77	34	10	10	NUM
admet-1885	77	35	ml	ml	NOUN
admet-1885	77	36	to	to	PART
admet-1885	77	37	get	get	VERB
admet-1885	77	38	theoretically	theoretically	ADV
admet-1885	77	39	20	20	NUM
admet-1885	77	40	µg	µg	ADJ
admet-1885	77	41	/	/	SYM
admet-1885	77	42	ml	ml	NOUN
admet-1885	77	43	solution	solution	NOUN
admet-1885	77	44	.	.	PUNCT
admet-1885	78	1	three	three	NUM
admet-1885	78	2	solutions	solution	NOUN
admet-1885	78	3	were	be	AUX
admet-1885	78	4	prepared	prepare	VERB
admet-1885	78	5	from	from	ADP
admet-1885	78	6	3	3	NUM
admet-1885	78	7	capsules	capsule	NOUN
admet-1885	78	8	and	and	CCONJ
admet-1885	78	9	measured	measure	VERB
admet-1885	78	10	spectrophotometrically	spectrophotometrically	ADV
admet-1885	78	11	at	at	ADP
admet-1885	78	12	278	278	NUM
admet-1885	78	13	nm	nm	NOUN
admet-1885	78	14	.	.	PUNCT
admet-1885	79	1	the	the	DET
admet-1885	79	2	other	other	ADJ
admet-1885	79	3	two	two	NUM
admet-1885	79	4	concentrations	concentration	NOUN
admet-1885	79	5	(	(	PUNCT
admet-1885	79	6	c	c	NOUN
admet-1885	79	7	)	)	PUNCT
admet-1885	79	8	were	be	AUX
admet-1885	79	9	prepared	prepare	VERB
admet-1885	79	10	,	,	PUNCT
admet-1885	79	11	50	50	NUM
admet-1885	79	12	and	and	CCONJ
admet-1885	79	13	100	100	NUM
admet-1885	79	14	µg	µg	ADV
admet-1885	79	15	/	/	SYM
admet-1885	79	16	ml	ml	NOUN
admet-1885	79	17	,	,	PUNCT
admet-1885	79	18	following	follow	VERB
admet-1885	79	19	the	the	DET
admet-1885	79	20	same	same	ADJ
admet-1885	79	21	procedure	procedure	NOUN
admet-1885	79	22	.	.	PUNCT
admet-1885	80	1	each	each	DET
admet-1885	80	2	time	time	NOUN
admet-1885	80	3	drug	drug	NOUN
admet-1885	80	4	recovery	recovery	NOUN
admet-1885	80	5	was	be	AUX
admet-1885	80	6	calculated	calculate	VERB
admet-1885	80	7	by	by	ADP
admet-1885	80	8	equation	equation	NOUN
admet-1885	80	9	(	(	PUNCT
admet-1885	80	10	1	1	NUM
admet-1885	80	11	)	)	PUNCT
admet-1885	80	12	,	,	PUNCT
admet-1885	80	13	in	in	ADP
admet-1885	80	14	addition	addition	NOUN
admet-1885	80	15	to	to	ADP
admet-1885	80	16	rsd	rsd	NOUN
admet-1885	80	17	as	as	ADP
admet-1885	80	18	a	a	DET
admet-1885	80	19	precision	precision	NOUN
admet-1885	80	20	parameter	parameter	NOUN
admet-1885	80	21	:	:	PUNCT
admet-1885	80	22	recovery	recovery	NOUN
admet-1885	80	23	=	=	PUNCT
admet-1885	80	24	(	(	PUNCT
admet-1885	80	25	cap	cap	NOUN
admet-1885	80	26	measured	measure	VERB
admet-1885	80	27	/	/	SYM
admet-1885	80	28	ctheoretical	ctheoretical	ADJ
admet-1885	80	29	)	)	PUNCT
admet-1885	80	30	100	100	NUM
admet-1885	80	31	(	(	PUNCT
admet-1885	80	32	1	1	X
admet-1885	80	33	)	)	PUNCT
admet-1885	80	34	robustness	robustness	NOUN
admet-1885	80	35	studies	study	NOUN
admet-1885	80	36	the	the	DET
admet-1885	80	37	effect	effect	NOUN
admet-1885	80	38	of	of	ADP
admet-1885	80	39	variation	variation	NOUN
admet-1885	80	40	in	in	ADP
admet-1885	80	41	conditions	condition	NOUN
admet-1885	80	42	on	on	ADP
admet-1885	80	43	the	the	DET
admet-1885	80	44	result	result	NOUN
admet-1885	80	45	.	.	PUNCT
admet-1885	81	1	different	different	ADJ
admet-1885	81	2	conditions	condition	NOUN
admet-1885	81	3	were	be	AUX
admet-1885	81	4	chosen	choose	VERB
admet-1885	81	5	for	for	ADP
admet-1885	81	6	measuring	measure	VERB
admet-1885	81	7	a	a	DET
admet-1885	81	8	sample	sample	NOUN
admet-1885	81	9	of	of	ADP
admet-1885	81	10	30	30	NUM
admet-1885	81	11	µg	µg	NOUN
admet-1885	81	12	/	/	SYM
admet-1885	81	13	ml	ml	NOUN
admet-1885	81	14	ap	ap	PROPN
admet-1885	81	15	.	.	PUNCT
admet-1885	82	1	conditions	condition	NOUN
admet-1885	82	2	such	such	ADJ
admet-1885	82	3	as	as	ADP
admet-1885	82	4	changing	change	VERB
admet-1885	82	5	the	the	DET
admet-1885	82	6	wavelength	wavelength	NOUN
admet-1885	82	7	±	±	PROPN
admet-1885	82	8	5	5	NUM
admet-1885	82	9	nm	nm	NOUN
admet-1885	82	10	and	and	CCONJ
admet-1885	82	11	warming	warming	NOUN
admet-1885	82	12	of	of	ADP
admet-1885	82	13	sample	sample	NOUN
admet-1885	82	14	test	test	NOUN
admet-1885	82	15	to	to	ADP
admet-1885	82	16	30	30	NUM
admet-1885	82	17	°	°	NOUN
admet-1885	82	18	c	c	NOUN
admet-1885	82	19	and	and	CCONJ
admet-1885	82	20	changing	change	VERB
admet-1885	82	21	the	the	DET
admet-1885	82	22	instruments	instrument	NOUN
admet-1885	82	23	from	from	ADP
admet-1885	82	24	other	other	ADJ
admet-1885	82	25	laboratories	laboratory	NOUN
admet-1885	82	26	were	be	AUX
admet-1885	82	27	used	use	VERB
admet-1885	82	28	(	(	PUNCT
admet-1885	82	29	medicinal	medicinal	ADJ
admet-1885	82	30	chemistry	chemistry	NOUN
admet-1885	82	31	lab	lab	NOUN
admet-1885	82	32	in	in	ADP
admet-1885	82	33	aau	aau	PROPN
admet-1885	82	34	)	)	PUNCT
admet-1885	82	35	.	.	PUNCT
admet-1885	83	1	other	other	ADJ
admet-1885	83	2	solvent	solvent	NOUN
admet-1885	83	3	was	be	AUX
admet-1885	83	4	used	use	VERB
admet-1885	83	5	(	(	PUNCT
admet-1885	83	6	methanol	methanol	NOUN
admet-1885	83	7	)	)	PUNCT
admet-1885	83	8	.	.	PUNCT
admet-1885	84	1	each	each	DET
admet-1885	84	2	sample	sample	NOUN
admet-1885	84	3	was	be	AUX
admet-1885	84	4	read	read	VERB
admet-1885	84	5	in	in	ADP
admet-1885	84	6	triplicate	triplicate	NOUN
admet-1885	84	7	and	and	CCONJ
admet-1885	84	8	accuracy	accuracy	NOUN
admet-1885	84	9	and	and	CCONJ
admet-1885	84	10	rsd	rsd	NOUN
admet-1885	84	11	were	be	AUX
admet-1885	84	12	calculated	calculate	VERB
admet-1885	84	13	.	.	PUNCT
admet-1885	85	1	preparation	preparation	NOUN
admet-1885	85	2	of	of	ADP
admet-1885	85	3	ap	ap	PROPN
admet-1885	85	4	-	-	PUNCT
admet-1885	85	5	βcd	βcd	NOUN
admet-1885	85	6	and	and	CCONJ
admet-1885	85	7	ap	ap	VERB
admet-1885	85	8	-	-	PUNCT
admet-1885	85	9	hpβcd	hpβcd	VERB
admet-1885	85	10	inclusion	inclusion	NOUN
admet-1885	85	11	complexes	complexe	VERB
admet-1885	85	12	all	all	DET
admet-1885	85	13	the	the	DET
admet-1885	85	14	following	follow	VERB
admet-1885	85	15	methods	method	NOUN
admet-1885	85	16	were	be	AUX
admet-1885	85	17	applied	apply	VERB
admet-1885	85	18	on	on	ADP
admet-1885	85	19	βcd	βcd	NOUN
admet-1885	85	20	and	and	CCONJ
admet-1885	85	21	hpβcd	hpβcd	ADJ
admet-1885	85	22	in	in	ADP
admet-1885	85	23	the	the	DET
admet-1885	85	24	same	same	ADJ
admet-1885	85	25	way	way	NOUN
admet-1885	85	26	and	and	CCONJ
admet-1885	85	27	3	3	NUM
admet-1885	85	28	different	different	ADJ
admet-1885	85	29	ratios	ratio	NOUN
admet-1885	85	30	(	(	PUNCT
admet-1885	85	31	1:1	1:1	NUM
admet-1885	85	32	,	,	PUNCT
admet-1885	85	33	1:2	1:2	NUM
admet-1885	85	34	,	,	PUNCT
admet-1885	85	35	and	and	CCONJ
admet-1885	85	36	1:3	1:3	NUM
admet-1885	85	37	w	w	PROPN
admet-1885	85	38	/	/	SYM
admet-1885	85	39	w	w	NOUN
admet-1885	85	40	)	)	PUNCT
admet-1885	85	41	.	.	PUNCT
admet-1885	86	1	kneading	kneading	NOUN
admet-1885	86	2	method	method	NOUN
admet-1885	86	3	in	in	ADP
admet-1885	86	4	the	the	DET
admet-1885	86	5	kneading	kneading	NOUN
admet-1885	86	6	method	method	NOUN
admet-1885	86	7	,	,	PUNCT
admet-1885	86	8	hpβcd	hpβcd	ADJ
admet-1885	86	9	or	or	CCONJ
admet-1885	86	10	βcd	βcd	NOUN
admet-1885	86	11	was	be	AUX
admet-1885	86	12	weighed	weigh	VERB
admet-1885	86	13	(	(	PUNCT
admet-1885	86	14	25	25	NUM
admet-1885	86	15	mg	mg	NUM
admet-1885	86	16	)	)	PUNCT
admet-1885	86	17	and	and	CCONJ
admet-1885	86	18	put	put	VERB
admet-1885	86	19	in	in	ADP
admet-1885	86	20	a	a	DET
admet-1885	86	21	mortar	mortar	NOUN
admet-1885	86	22	,	,	PUNCT
admet-1885	86	23	then	then	ADV
admet-1885	86	24	mixed	mix	VERB
admet-1885	86	25	with	with	ADP
admet-1885	86	26	enough	enough	ADJ
admet-1885	86	27	amount	amount	NOUN
admet-1885	86	28	of	of	ADP
admet-1885	86	29	water	water	NOUN
admet-1885	86	30	-	-	PUNCT
admet-1885	86	31	ethanol	ethanol	NOUN
admet-1885	86	32	mixture	mixture	NOUN
admet-1885	86	33	to	to	PART
admet-1885	86	34	get	get	VERB
admet-1885	86	35	a	a	DET
admet-1885	86	36	thick	thick	ADJ
admet-1885	86	37	paste	paste	NOUN
admet-1885	86	38	.	.	PUNCT
admet-1885	87	1	to	to	ADP
admet-1885	87	2	this	this	DET
admet-1885	87	3	paste	paste	NOUN
admet-1885	87	4	,	,	PUNCT
admet-1885	87	5	ap	ap	PROPN
admet-1885	87	6	was	be	AUX
admet-1885	87	7	gradually	gradually	ADV
admet-1885	87	8	incorporated	incorporate	VERB
admet-1885	87	9	in	in	ADP
admet-1885	87	10	a	a	DET
admet-1885	87	11	total	total	NOUN
admet-1885	87	12	of	of	ADP
admet-1885	87	13	up	up	ADP
admet-1885	87	14	to	to	PART
admet-1885	87	15	(	(	PUNCT
admet-1885	87	16	25	25	NUM
admet-1885	87	17	mg	mg	NUM
admet-1885	87	18	)	)	PUNCT
admet-1885	87	19	.	.	PUNCT
admet-1885	88	1	the	the	DET
admet-1885	88	2	kneading	kneading	NOUN
admet-1885	88	3	process	process	NOUN
admet-1885	88	4	was	be	AUX
admet-1885	88	5	continued	continue	VERB
admet-1885	88	6	for	for	ADP
admet-1885	88	7	1	1	NUM
admet-1885	88	8	hour	hour	NOUN
admet-1885	88	9	manually	manually	ADV
admet-1885	88	10	in	in	ADP
admet-1885	88	11	one	one	NUM
admet-1885	88	12	direction	direction	NOUN
admet-1885	88	13	.	.	PUNCT
admet-1885	89	1	later	later	ADV
admet-1885	89	2	,	,	PUNCT
admet-1885	89	3	enough	enough	ADJ
admet-1885	89	4	solvent	solvent	NOUN
admet-1885	89	5	was	be	AUX
admet-1885	89	6	mixed	mix	VERB
admet-1885	89	7	to	to	PART
admet-1885	89	8	have	have	VERB
admet-1885	89	9	a	a	DET
admet-1885	89	10	consistent	consistent	ADJ
admet-1885	89	11	paste	paste	NOUN
admet-1885	89	12	,	,	PUNCT
admet-1885	89	13	and	and	CCONJ
admet-1885	89	14	then	then	ADV
admet-1885	89	15	it	it	PRON
admet-1885	89	16	was	be	AUX
admet-1885	89	17	dried	dry	VERB
admet-1885	89	18	at	at	ADP
admet-1885	89	19	40	40	NUM
admet-1885	89	20	°	°	NOUN
admet-1885	89	21	c	c	NOUN
admet-1885	89	22	for	for	ADP
admet-1885	89	23	48	48	NUM
admet-1885	89	24	hours	hour	NOUN
admet-1885	89	25	in	in	ADP
admet-1885	89	26	(	(	PUNCT
admet-1885	89	27	memert	memert	ADJ
admet-1885	89	28	oven	oven	NOUN
admet-1885	89	29	)	)	PUNCT
admet-1885	89	30	.	.	PUNCT
admet-1885	90	1	then	then	ADV
admet-1885	90	2	,	,	PUNCT
admet-1885	90	3	the	the	DET
admet-1885	90	4	dried	dry	VERB
admet-1885	90	5	mixture	mixture	NOUN
admet-1885	90	6	was	be	AUX
admet-1885	90	7	crushed	crush	VERB
admet-1885	90	8	gently	gently	ADV
admet-1885	90	9	using	use	VERB
admet-1885	90	10	the	the	DET
admet-1885	90	11	mortar	mortar	NOUN
admet-1885	90	12	and	and	CCONJ
admet-1885	90	13	pestle	pestle	NOUN
admet-1885	90	14	.	.	PUNCT
admet-1885	91	1	the	the	DET
admet-1885	91	2	scratched	scratched	ADJ
admet-1885	91	3	mixture	mixture	NOUN
admet-1885	91	4	was	be	AUX
admet-1885	91	5	sieved	sieve	VERB
admet-1885	91	6	using	use	VERB
admet-1885	91	7	a	a	DET
admet-1885	91	8	mesh	mesh	NOUN
admet-1885	91	9	sieve	sieve	NOUN
admet-1885	91	10	(	(	PUNCT
admet-1885	91	11	#	#	SYM
admet-1885	91	12	65	65	NUM
admet-1885	91	13	)	)	PUNCT
admet-1885	91	14	.	.	PUNCT
admet-1885	92	1	then	then	ADV
admet-1885	92	2	,	,	PUNCT
admet-1885	92	3	the	the	DET
admet-1885	92	4	formed	form	VERB
admet-1885	92	5	complex	complex	NOUN
admet-1885	92	6	was	be	AUX
admet-1885	92	7	stored	store	VERB
admet-1885	92	8	in	in	ADP
admet-1885	92	9	a	a	DET
admet-1885	92	10	closed	closed	ADJ
admet-1885	92	11	container	container	NOUN
admet-1885	92	12	.	.	PUNCT
admet-1885	93	1	the	the	DET
admet-1885	93	2	above	above	ADJ
admet-1885	93	3	procedure	procedure	NOUN
admet-1885	93	4	was	be	AUX
admet-1885	93	5	repeated	repeat	VERB
admet-1885	93	6	to	to	PART
admet-1885	93	7	make	make	VERB
admet-1885	93	8	the	the	DET
admet-1885	93	9	weight	weight	NOUN
admet-1885	93	10	ratios	ratio	NOUN
admet-1885	93	11	of	of	ADP
admet-1885	93	12	1:1	1:1	NUM
admet-1885	93	13	,	,	PUNCT
admet-1885	93	14	1:2	1:2	NUM
admet-1885	93	15	,	,	PUNCT
admet-1885	93	16	1:3	1:3	NUM
admet-1885	93	17	for	for	ADP
admet-1885	93	18	both	both	DET
admet-1885	93	19	βcd	βcd	NOUN
admet-1885	93	20	and	and	CCONJ
admet-1885	93	21	hpβcd	hpβcd	ADJ
admet-1885	93	22	.	.	PUNCT
admet-1885	94	1	solvent	solvent	ADJ
admet-1885	94	2	evaporation	evaporation	NOUN
admet-1885	94	3	method	method	NOUN
admet-1885	94	4	in	in	ADP
admet-1885	94	5	this	this	DET
admet-1885	94	6	method	method	NOUN
admet-1885	94	7	,	,	PUNCT
admet-1885	94	8	25	25	NUM
admet-1885	94	9	mg	mg	NOUN
admet-1885	94	10	ap	ap	PROPN
admet-1885	94	11	was	be	AUX
admet-1885	94	12	dissolved	dissolve	VERB
admet-1885	94	13	in	in	ADP
admet-1885	94	14	50	50	NUM
admet-1885	94	15	ml	ml	NOUN
admet-1885	94	16	ethanol	ethanol	NOUN
admet-1885	94	17	.	.	PUNCT
admet-1885	95	1	the	the	DET
admet-1885	95	2	specified	specify	VERB
admet-1885	95	3	amount	amount	NOUN
admet-1885	95	4	of	of	ADP
admet-1885	95	5	βcd	βcd	NOUN
admet-1885	95	6	or	or	CCONJ
admet-1885	95	7	hpβcd	hpβcd	ADJ
admet-1885	95	8	was	be	AUX
admet-1885	95	9	dissolved	dissolve	VERB
admet-1885	95	10	in	in	ADP
admet-1885	95	11	25	25	NUM
admet-1885	95	12	ml	ml	NOUN
admet-1885	95	13	of	of	ADP
admet-1885	95	14	distilled	distil	VERB
admet-1885	95	15	water	water	NOUN
admet-1885	95	16	.	.	PUNCT
admet-1885	96	1	the	the	DET
admet-1885	96	2	above	above	ADV
admet-1885	96	3	-	-	PUNCT
admet-1885	96	4	prepared	prepare	VERB
admet-1885	96	5	solutions	solution	NOUN
admet-1885	96	6	were	be	AUX
admet-1885	96	7	mixed	mix	VERB
admet-1885	96	8	with	with	ADP
admet-1885	96	9	the	the	DET
admet-1885	96	10	help	help	NOUN
admet-1885	96	11	of	of	ADP
admet-1885	96	12	a	a	DET
admet-1885	96	13	magnetic	magnetic	ADJ
admet-1885	96	14	stirrer	stirrer	NOUN
admet-1885	96	15	,	,	PUNCT
admet-1885	96	16	and	and	CCONJ
admet-1885	96	17	then	then	ADV
admet-1885	96	18	the	the	DET
admet-1885	96	19	mixture	mixture	NOUN
admet-1885	96	20	was	be	AUX
admet-1885	96	21	stirred	stir	VERB
admet-1885	96	22	for	for	ADP
admet-1885	96	23	8	8	NUM
admet-1885	96	24	hours	hour	NOUN
admet-1885	96	25	.	.	PUNCT
admet-1885	97	1	later	later	ADV
admet-1885	97	2	,	,	PUNCT
admet-1885	97	3	most	most	ADJ
admet-1885	97	4	of	of	ADP
admet-1885	97	5	the	the	DET
admet-1885	97	6	solvent	solvent	NOUN
admet-1885	97	7	was	be	AUX
admet-1885	97	8	removed	remove	VERB
admet-1885	97	9	using	use	VERB
admet-1885	97	10	a	a	DET
admet-1885	97	11	rotary	rotary	ADJ
admet-1885	97	12	evaporator	evaporator	NOUN
admet-1885	97	13	(	(	PUNCT
admet-1885	97	14	heating	heat	VERB
admet-1885	97	15	at	at	ADP
admet-1885	97	16	50	50	NUM
admet-1885	97	17	°	°	NOUN
admet-1885	97	18	c	c	NOUN
admet-1885	97	19	)	)	PUNCT
admet-1885	97	20	at	at	ADP
admet-1885	97	21	constant	constant	ADJ
admet-1885	97	22	stirring	stirring	NOUN
admet-1885	97	23	.	.	PUNCT
admet-1885	98	1	reduced	reduce	VERB
admet-1885	98	2	pressure	pressure	NOUN
admet-1885	98	3	was	be	AUX
admet-1885	98	4	applied	apply	VERB
admet-1885	98	5	to	to	PART
admet-1885	98	6	remove	remove	VERB
admet-1885	98	7	the	the	DET
admet-1885	98	8	residual	residual	ADJ
admet-1885	98	9	solvent	solvent	NOUN
admet-1885	98	10	from	from	ADP
admet-1885	98	11	the	the	DET
admet-1885	98	12	mixture	mixture	NOUN
admet-1885	98	13	.	.	PUNCT
admet-1885	99	1	the	the	DET
admet-1885	99	2	final	final	ADJ
admet-1885	99	3	product	product	NOUN
admet-1885	99	4	was	be	AUX
admet-1885	99	5	placed	place	VERB
admet-1885	99	6	in	in	ADP
admet-1885	99	7	an	an	DET
admet-1885	99	8	oven	oven	NOUN
admet-1885	99	9	at	at	ADP
admet-1885	99	10	40	40	NUM
admet-1885	99	11	°	°	NOUN
admet-1885	99	12	c	c	NOUN
admet-1885	99	13	for	for	ADP
admet-1885	99	14	48	48	NUM
admet-1885	99	15	hours	hour	NOUN
admet-1885	99	16	to	to	PART
admet-1885	99	17	eliminate	eliminate	VERB
admet-1885	99	18	the	the	DET
admet-1885	99	19	excess	excess	ADJ
admet-1885	99	20	solvent	solvent	NOUN
admet-1885	99	21	.	.	PUNCT
admet-1885	100	1	the	the	DET
admet-1885	100	2	mixture	mixture	NOUN
admet-1885	100	3	was	be	AUX
admet-1885	100	4	scratched	scratch	VERB
admet-1885	100	5	and	and	CCONJ
admet-1885	100	6	sieved	sieve	VERB
admet-1885	100	7	using	use	VERB
admet-1885	100	8	a	a	DET
admet-1885	100	9	mesh	mesh	NOUN
admet-1885	100	10	sieve	sieve	NOUN
admet-1885	100	11	(	(	PUNCT
admet-1885	100	12	#	#	SYM
admet-1885	100	13	65	65	NUM
admet-1885	100	14	)	)	PUNCT
admet-1885	100	15	and	and	CCONJ
admet-1885	100	16	then	then	ADV
admet-1885	100	17	stored	store	VERB
admet-1885	100	18	in	in	ADP
admet-1885	100	19	a	a	DET
admet-1885	100	20	tightly	tightly	ADV
admet-1885	100	21	closed	close	VERB
admet-1885	100	22	container	container	NOUN
admet-1885	100	23	.	.	PUNCT
admet-1885	101	1	the	the	DET
admet-1885	101	2	above	above	ADJ
admet-1885	101	3	procedure	procedure	NOUN
admet-1885	101	4	was	be	AUX
admet-1885	101	5	repeated	repeat	VERB
admet-1885	101	6	to	to	PART
admet-1885	101	7	make	make	VERB
admet-1885	101	8	the	the	DET
admet-1885	101	9	ratios	ratio	NOUN
admet-1885	101	10	of	of	ADP
admet-1885	101	11	1:1	1:1	NUM
admet-1885	101	12	,	,	PUNCT
admet-1885	101	13	1:2	1:2	NUM
admet-1885	101	14	,	,	PUNCT
admet-1885	101	15	1:3	1:3	NUM
admet-1885	101	16	for	for	ADP
admet-1885	101	17	both	both	DET
admet-1885	101	18	βcd	βcd	NOUN
admet-1885	101	19	and	and	CCONJ
admet-1885	101	20	hpβcd	hpβcd	PROPN
admet-1885	101	21	.	.	PUNCT
admet-1885	102	1	spray	spray	VERB
admet-1885	102	2	drying	dry	VERB
admet-1885	102	3	method	method	NOUN
admet-1885	102	4	buchi	buchi	PROPN
admet-1885	102	5	nano	nano	NOUN
admet-1885	102	6	spray	spray	VERB
admet-1885	102	7	dryer	dryer	NOUN
admet-1885	102	8	b-90	b-90	PROPN
admet-1885	102	9	hp	hp	NOUN
admet-1885	102	10	was	be	AUX
admet-1885	102	11	used	use	VERB
admet-1885	102	12	to	to	PART
admet-1885	102	13	perform	perform	VERB
admet-1885	102	14	the	the	DET
admet-1885	102	15	spray	spray	NOUN
admet-1885	102	16	drying	dry	VERB
admet-1885	102	17	method	method	NOUN
admet-1885	102	18	.	.	PUNCT
admet-1885	103	1	ap	ap	PROPN
admet-1885	103	2	was	be	AUX
admet-1885	103	3	dissolved	dissolve	VERB
admet-1885	103	4	in	in	ADP
admet-1885	103	5	ethanol	ethanol	NOUN
admet-1885	103	6	(	(	PUNCT
admet-1885	103	7	50	50	NUM
admet-1885	103	8	ml	ml	NOUN
admet-1885	103	9	)	)	PUNCT
admet-1885	103	10	,	,	PUNCT
admet-1885	103	11	then	then	ADV
admet-1885	103	12	hpβcd	hpβcd	VERB
admet-1885	103	13	or	or	CCONJ
admet-1885	103	14	βcd	βcd	NOUN
admet-1885	103	15	was	be	AUX
admet-1885	103	16	dissolved	dissolve	VERB
admet-1885	103	17	in	in	ADP
admet-1885	103	18	distilled	distil	VERB
admet-1885	103	19	water	water	NOUN
admet-1885	103	20	(	(	PUNCT
admet-1885	103	21	50	50	NUM
admet-1885	103	22	ml	ml	NOUN
admet-1885	103	23	)	)	PUNCT
admet-1885	103	24	.	.	PUNCT
admet-1885	104	1	the	the	DET
admet-1885	104	2	two	two	NUM
admet-1885	104	3	mixtures	mixture	NOUN
admet-1885	104	4	were	be	AUX
admet-1885	104	5	combined	combine	VERB
admet-1885	104	6	by	by	ADP
admet-1885	104	7	sonication	sonication	NOUN
admet-1885	104	8	for	for	ADP
admet-1885	104	9	20	20	NUM
admet-1885	104	10	minutes	minute	NOUN
admet-1885	104	11	to	to	PART
admet-1885	104	12	provide	provide	VERB
admet-1885	104	13	a	a	DET
admet-1885	104	14	clear	clear	ADJ
admet-1885	104	15	final	final	ADJ
admet-1885	104	16	solution	solution	NOUN
admet-1885	104	17	.	.	PUNCT
admet-1885	105	1	later	later	ADV
admet-1885	105	2	,	,	PUNCT
admet-1885	105	3	the	the	DET
admet-1885	105	4	solution	solution	NOUN
admet-1885	105	5	was	be	AUX
admet-1885	105	6	undergone	undergo	VERB
admet-1885	105	7	for	for	ADP
admet-1885	105	8	spray	spray	NOUN
admet-1885	105	9	dry	dry	ADJ
admet-1885	105	10	process	process	NOUN
admet-1885	105	11	,	,	PUNCT
admet-1885	105	12	and	and	CCONJ
admet-1885	105	13	the	the	DET
admet-1885	105	14	drying	dry	VERB
admet-1885	105	15	conditions	condition	NOUN
admet-1885	105	16	were	be	AUX
admet-1885	105	17	as	as	SCONJ
admet-1885	105	18	follows	follow	VERB
admet-1885	105	19	:	:	PUNCT
admet-1885	105	20	temperature	temperature	NOUN
admet-1885	105	21	(	(	PUNCT
admet-1885	105	22	outlet	outlet	PROPN
admet-1885	105	23	)	)	PUNCT
admet-1885	105	24	;	;	PUNCT
admet-1885	105	25	90	90	NUM
admet-1885	105	26	°	°	NOUN
admet-1885	105	27	c	c	NOUN
admet-1885	105	28	,	,	PUNCT
admet-1885	105	29	temperature	temperature	NOUN
admet-1885	105	30	(	(	PUNCT
admet-1885	105	31	inlet	inlet	NOUN
admet-1885	105	32	)	)	PUNCT
admet-1885	105	33	;	;	PUNCT
admet-1885	106	1	168	168	NUM
admet-1885	106	2	°	°	NOUN
admet-1885	106	3	c	c	NOUN
admet-1885	106	4	,	,	PUNCT
admet-1885	106	5	flow	flow	NOUN
admet-1885	106	6	rate	rate	NOUN
admet-1885	106	7	(	(	PUNCT
admet-1885	106	8	solution	solution	NOUN
admet-1885	106	9	)	)	PUNCT
admet-1885	106	10	1000	1000	NUM
admet-1885	106	11	ml	ml	NOUN
admet-1885	106	12	/	/	SYM
admet-1885	106	13	h	h	NOUN
admet-1885	106	14	;	;	PUNCT
admet-1885	106	15	flow	flow	NOUN
admet-1885	106	16	rate	rate	NOUN
admet-1885	106	17	(	(	PUNCT
admet-1885	106	18	air	air	NOUN
admet-1885	106	19	)	)	PUNCT
admet-1885	106	20	400	400	NUM
admet-1885	106	21	ml	ml	NOUN
admet-1885	106	22	/	/	SYM
admet-1885	106	23	h.	h.	NOUN
admet-1885	106	24	the	the	DET
admet-1885	106	25	final	final	ADJ
admet-1885	106	26	inclusion	inclusion	NOUN
admet-1885	106	27	complex	complex	NOUN
admet-1885	106	28	was	be	AUX
admet-1885	106	29	crushed	crush	VERB
admet-1885	106	30	and	and	CCONJ
admet-1885	106	31	sieved	sieve	VERB
admet-1885	106	32	using	use	VERB
admet-1885	106	33	sieve	sieve	NOUN
admet-1885	106	34	mesh	mesh	NOUN
admet-1885	106	35	size	size	NOUN
admet-1885	106	36	#	#	SYM
admet-1885	106	37	65	65	NUM
admet-1885	106	38	.	.	PUNCT
admet-1885	107	1	after	after	ADP
admet-1885	107	2	sieving	sieving	NOUN
admet-1885	107	3	,	,	PUNCT
admet-1885	107	4	the	the	DET
admet-1885	107	5	inclusion	inclusion	NOUN
admet-1885	107	6	complex	complex	NOUN
admet-1885	107	7	was	be	AUX
admet-1885	107	8	stored	store	VERB
admet-1885	107	9	in	in	ADP
admet-1885	107	10	a	a	DET
admet-1885	107	11	tight	tight	ADJ
admet-1885	107	12	container	container	NOUN
admet-1885	107	13	.	.	PUNCT
admet-1885	108	1	the	the	DET
admet-1885	108	2	above	above	ADJ
admet-1885	108	3	procedure	procedure	NOUN
admet-1885	108	4	was	be	AUX
admet-1885	108	5	repeated	repeat	VERB
admet-1885	108	6	to	to	PART
admet-1885	108	7	make	make	VERB
admet-1885	108	8	the	the	DET
admet-1885	108	9	ratios	ratio	NOUN
admet-1885	108	10	(	(	PUNCT
admet-1885	108	11	1:1	1:1	NUM
admet-1885	108	12	,	,	PUNCT
admet-1885	108	13	1:2	1:2	NUM
admet-1885	108	14	,	,	PUNCT
admet-1885	108	15	1:3	1:3	NUM
admet-1885	108	16	)	)	PUNCT
admet-1885	108	17	and	and	CCONJ
admet-1885	108	18	for	for	ADP
admet-1885	108	19	both	both	DET
admet-1885	108	20	βcd	βcd	NOUN
admet-1885	108	21	and	and	CCONJ
admet-1885	108	22	hpβcd	hpβcd	ADJ
admet-1885	108	23	.	.	PUNCT
admet-1885	109	1	admet	admet	PROPN
admet-1885	109	2	&	&	CCONJ
admet-1885	109	3	dmpk	dmpk	PROPN
admet-1885	109	4	11(4	11(4	NUM
admet-1885	109	5	)	)	PUNCT
admet-1885	109	6	(	(	PUNCT
admet-1885	109	7	2023	2023	NUM
admet-1885	109	8	)	)	PUNCT
admet-1885	109	9	533	533	NUM
admet-1885	109	10	-	-	SYM
admet-1885	109	11	550	550	NUM
admet-1885	109	12	enhancement	enhancement	NOUN
admet-1885	109	13	of	of	ADP
admet-1885	109	14	apixaban	apixaban	ADJ
admet-1885	109	15	solubility	solubility	NOUN
admet-1885	109	16	by	by	ADP
admet-1885	109	17	cyclodextrins	cyclodextrin	NOUN
admet-1885	109	18	doi	doi	PROPN
admet-1885	109	19	:	:	PUNCT
admet-1885	109	20	https://doi.org/10.5599/adme	https://doi.org/10.5599/adme	NOUN
admet-1885	109	21	t.1885	t.1885	NOUN
admet-1885	109	22	537	537	NUM
admet-1885	109	23	characterization	characterization	NOUN
admet-1885	109	24	of	of	ADP
admet-1885	109	25	the	the	DET
admet-1885	109	26	prepared	prepared	ADJ
admet-1885	109	27	complex	complex	NOUN
admet-1885	109	28	after	after	ADP
admet-1885	109	29	the	the	DET
admet-1885	109	30	preparation	preparation	NOUN
admet-1885	109	31	of	of	ADP
admet-1885	109	32	the	the	DET
admet-1885	109	33	eighteen	eighteen	NUM
admet-1885	109	34	samples	sample	NOUN
admet-1885	109	35	of	of	ADP
admet-1885	109	36	ap	ap	PROPN
admet-1885	109	37	-	-	PUNCT
admet-1885	109	38	cd	cd	PROPN
admet-1885	109	39	and	and	CCONJ
admet-1885	109	40	aphpβcd	aphpβcd	ADJ
admet-1885	109	41	complexes	complex	NOUN
admet-1885	109	42	,	,	PUNCT
admet-1885	109	43	they	they	PRON
admet-1885	109	44	were	be	AUX
admet-1885	109	45	characterized	characterize	VERB
admet-1885	109	46	by	by	ADP
admet-1885	109	47	the	the	DET
admet-1885	109	48	following	following	ADJ
admet-1885	109	49	methods	method	NOUN
admet-1885	109	50	:	:	PUNCT
admet-1885	109	51	fourier	fourier	NOUN
admet-1885	109	52	transform	transform	VERB
admet-1885	109	53	infrared	infrared	ADJ
admet-1885	109	54	spectroscopy	spectroscopy	NOUN
admet-1885	109	55	(	(	PUNCT
admet-1885	109	56	ftir	ftir	PROPN
admet-1885	109	57	)	)	PUNCT
admet-1885	109	58	ftir	ftir	PROPN
admet-1885	109	59	was	be	AUX
admet-1885	109	60	used	use	VERB
admet-1885	109	61	as	as	ADP
admet-1885	109	62	a	a	DET
admet-1885	109	63	characterization	characterization	NOUN
admet-1885	109	64	technique	technique	NOUN
admet-1885	109	65	for	for	ADP
admet-1885	109	66	the	the	DET
admet-1885	109	67	formation	formation	NOUN
admet-1885	109	68	of	of	ADP
admet-1885	109	69	complexes	complex	NOUN
admet-1885	109	70	.	.	PUNCT
admet-1885	110	1	ap	ap	PROPN
admet-1885	110	2	,	,	PUNCT
admet-1885	110	3	βcd	βcd	NOUN
admet-1885	110	4	and	and	CCONJ
admet-1885	110	5	hpβcd	hpβcd	NUM
admet-1885	110	6	,	,	PUNCT
admet-1885	110	7	and	and	CCONJ
admet-1885	110	8	the	the	DET
admet-1885	110	9	prepared	prepared	ADJ
admet-1885	110	10	complexes	complex	NOUN
admet-1885	110	11	were	be	AUX
admet-1885	110	12	scanned	scan	VERB
admet-1885	110	13	separately	separately	ADV
admet-1885	110	14	to	to	PART
admet-1885	110	15	detect	detect	VERB
admet-1885	110	16	the	the	DET
admet-1885	110	17	changes	change	NOUN
admet-1885	110	18	and	and	CCONJ
admet-1885	110	19	identify	identify	VERB
admet-1885	110	20	peaks	peak	NOUN
admet-1885	110	21	(	(	PUNCT
admet-1885	110	22	only	only	ADV
admet-1885	110	23	a	a	DET
admet-1885	110	24	representative	representative	ADJ
admet-1885	110	25	chart	chart	NOUN
admet-1885	110	26	is	be	AUX
admet-1885	110	27	included	include	VERB
admet-1885	110	28	)	)	PUNCT
admet-1885	110	29	.	.	PUNCT
admet-1885	111	1	differential	differential	PROPN
admet-1885	111	2	scanning	scan	VERB
admet-1885	111	3	calorimetry	calorimetry	NOUN
admet-1885	111	4	(	(	PUNCT
admet-1885	111	5	dsc	dsc	NOUN
admet-1885	111	6	)	)	PUNCT
admet-1885	111	7	dsc	dsc	NOUN
admet-1885	111	8	was	be	AUX
admet-1885	111	9	performed	perform	VERB
admet-1885	111	10	on	on	ADP
admet-1885	111	11	selected	select	VERB
admet-1885	111	12	samples	sample	NOUN
admet-1885	111	13	for	for	ADP
admet-1885	111	14	further	further	ADJ
admet-1885	111	15	confirmation	confirmation	NOUN
admet-1885	111	16	.	.	PUNCT
admet-1885	112	1	dsc	dsc	NOUN
admet-1885	112	2	(	(	PUNCT
admet-1885	112	3	model	model	NOUN
admet-1885	112	4	dt-60	dt-60	ADP
admet-1885	112	5	,	,	PUNCT
admet-1885	112	6	shimadzu	shimadzu	NOUN
admet-1885	112	7	)	)	PUNCT
admet-1885	112	8	was	be	AUX
admet-1885	112	9	used	use	VERB
admet-1885	112	10	to	to	PART
admet-1885	112	11	perform	perform	VERB
admet-1885	112	12	this	this	DET
admet-1885	112	13	test	test	NOUN
admet-1885	112	14	.	.	PUNCT
admet-1885	113	1	ap	ap	PROPN
admet-1885	113	2	,	,	PUNCT
admet-1885	113	3	ap	ap	PROPN
admet-1885	113	4	-	-	PUNCT
admet-1885	113	5	βcd	βcd	NOUN
admet-1885	113	6	,	,	PUNCT
admet-1885	113	7	and	and	CCONJ
admet-1885	113	8	the	the	DET
admet-1885	113	9	ap	ap	ADJ
admet-1885	113	10	-	-	PUNCT
admet-1885	113	11	hpβcd	hpβcd	ADJ
admet-1885	113	12	complex	complex	NOUN
admet-1885	113	13	were	be	AUX
admet-1885	113	14	scanned	scan	VERB
admet-1885	113	15	from	from	ADP
admet-1885	113	16	0	0	NUM
admet-1885	113	17	–	–	PUNCT
admet-1885	113	18	360	360	NUM
admet-1885	113	19	oc	oc	NOUN
admet-1885	113	20	at	at	ADP
admet-1885	113	21	10	10	NUM
admet-1885	113	22	oc	oc	NOUN
admet-1885	113	23	/	/	SYM
admet-1885	113	24	min	min	NOUN
admet-1885	113	25	.	.	PROPN
admet-1885	113	26	thermograms	thermogram	NOUN
admet-1885	113	27	were	be	AUX
admet-1885	113	28	recorded	record	VERB
admet-1885	113	29	and	and	CCONJ
admet-1885	113	30	examined	examine	VERB
admet-1885	113	31	.	.	PUNCT
admet-1885	114	1	percent	percent	NOUN
admet-1885	114	2	yield	yield	NOUN
admet-1885	114	3	of	of	ADP
admet-1885	114	4	the	the	DET
admet-1885	114	5	prepared	prepared	ADJ
admet-1885	114	6	complex	complex	NOUN
admet-1885	114	7	the	the	DET
admet-1885	114	8	yield	yield	NOUN
admet-1885	114	9	(	(	PUNCT
admet-1885	114	10	%	%	NOUN
admet-1885	114	11	)	)	PUNCT
admet-1885	114	12	of	of	ADP
admet-1885	114	13	each	each	DET
admet-1885	114	14	prepared	prepare	VERB
admet-1885	114	15	complex	complex	NOUN
admet-1885	114	16	was	be	AUX
admet-1885	114	17	calculated	calculate	VERB
admet-1885	114	18	as	as	ADP
admet-1885	114	19	follows	follow	NOUN
admet-1885	114	20	,	,	PUNCT
admet-1885	114	21	equation	equation	NOUN
admet-1885	114	22	(	(	PUNCT
admet-1885	114	23	2	2	NUM
admet-1885	114	24	):	):	PUNCT
admet-1885	114	25	yield	yield	NOUN
admet-1885	114	26	=	=	SYM
admet-1885	114	27	(	(	PUNCT
admet-1885	114	28	practical	practical	ADJ
admet-1885	114	29	weight	weight	NOUN
admet-1885	114	30	of	of	ADP
admet-1885	114	31	the	the	DET
admet-1885	114	32	product/	product/	NUM
admet-1885	114	33	theoretical	theoretical	ADJ
admet-1885	114	34	weight	weight	NOUN
admet-1885	114	35	(	(	PUNCT
admet-1885	114	36	drug	drug	NOUN
admet-1885	114	37	+	+	SYM
admet-1885	114	38	cd	cd	PROPN
admet-1885	114	39	)	)	PUNCT
admet-1885	114	40	)	)	PUNCT
admet-1885	114	41	100	100	NUM
admet-1885	114	42	(	(	PUNCT
admet-1885	114	43	2	2	NUM
admet-1885	114	44	)	)	PUNCT
admet-1885	114	45	percent	percent	NOUN
admet-1885	114	46	drug	drug	NOUN
admet-1885	114	47	content	content	NOUN
admet-1885	114	48	in	in	ADP
admet-1885	114	49	the	the	DET
admet-1885	114	50	prepared	prepared	ADJ
admet-1885	114	51	complex	complex	NOUN
admet-1885	114	52	this	this	DET
admet-1885	114	53	test	test	NOUN
admet-1885	114	54	will	will	AUX
admet-1885	114	55	give	give	VERB
admet-1885	114	56	the	the	DET
admet-1885	114	57	efficiency	efficiency	NOUN
admet-1885	114	58	of	of	ADP
admet-1885	114	59	the	the	DET
admet-1885	114	60	complexation	complexation	NOUN
admet-1885	114	61	process	process	NOUN
admet-1885	114	62	.	.	PUNCT
admet-1885	115	1	it	it	PRON
admet-1885	115	2	also	also	ADV
admet-1885	115	3	reflects	reflect	VERB
admet-1885	115	4	the	the	DET
admet-1885	115	5	efficiency	efficiency	NOUN
admet-1885	115	6	of	of	ADP
admet-1885	115	7	the	the	DET
admet-1885	115	8	method	method	NOUN
admet-1885	115	9	.	.	PUNCT
admet-1885	116	1	for	for	ADP
admet-1885	116	2	all	all	DET
admet-1885	116	3	types	type	NOUN
admet-1885	116	4	of	of	ADP
admet-1885	116	5	complexes	complex	NOUN
admet-1885	116	6	prepared	prepare	VERB
admet-1885	116	7	,	,	PUNCT
admet-1885	116	8	the	the	DET
admet-1885	116	9	percent	percent	NOUN
admet-1885	116	10	ap	ap	NOUN
admet-1885	116	11	in	in	ADP
admet-1885	116	12	the	the	DET
admet-1885	116	13	complex	complex	NOUN
admet-1885	116	14	was	be	AUX
admet-1885	116	15	determined	determine	VERB
admet-1885	116	16	by	by	ADP
admet-1885	116	17	dissolving	dissolve	VERB
admet-1885	116	18	an	an	DET
admet-1885	116	19	amount	amount	NOUN
admet-1885	116	20	of	of	ADP
admet-1885	116	21	complex	complex	ADJ
admet-1885	116	22	equivalent	equivalent	NOUN
admet-1885	116	23	to	to	ADP
admet-1885	116	24	a	a	DET
admet-1885	116	25	specified	specify	VERB
admet-1885	116	26	amount	amount	NOUN
admet-1885	116	27	of	of	ADP
admet-1885	116	28	ap	ap	PROPN
admet-1885	116	29	(	(	PUNCT
admet-1885	116	30	25	25	NUM
admet-1885	116	31	mg	mg	NOUN
admet-1885	116	32	)	)	PUNCT
admet-1885	116	33	in	in	ADP
admet-1885	116	34	50	50	NUM
admet-1885	116	35	ml	ml	NOUN
admet-1885	116	36	distilled	distil	VERB
admet-1885	116	37	water	water	NOUN
admet-1885	116	38	and	and	CCONJ
admet-1885	116	39	shaking	shake	VERB
admet-1885	116	40	for	for	ADP
admet-1885	116	41	1	1	NUM
admet-1885	116	42	hour	hour	NOUN
admet-1885	116	43	.	.	PUNCT
admet-1885	117	1	several	several	ADJ
admet-1885	117	2	amounts	amount	NOUN
admet-1885	117	3	were	be	AUX
admet-1885	117	4	tried	try	VERB
admet-1885	117	5	that	that	PRON
admet-1885	117	6	gave	give	VERB
admet-1885	117	7	a	a	DET
admet-1885	117	8	clear	clear	ADJ
admet-1885	117	9	solution	solution	NOUN
admet-1885	117	10	.	.	PUNCT
admet-1885	118	1	then	then	ADV
admet-1885	118	2	50	50	NUM
admet-1885	118	3	ml	ml	NOUN
admet-1885	118	4	ethanol	ethanol	NOUN
admet-1885	118	5	was	be	AUX
admet-1885	118	6	added	add	VERB
admet-1885	118	7	and	and	CCONJ
admet-1885	118	8	stirred	stir	VERB
admet-1885	118	9	for	for	ADP
admet-1885	118	10	2	2	NUM
admet-1885	118	11	hours	hour	NOUN
admet-1885	118	12	to	to	PART
admet-1885	118	13	dissolve	dissolve	VERB
admet-1885	118	14	ap	ap	PROPN
admet-1885	118	15	.	.	PUNCT
admet-1885	119	1	suitable	suitable	ADJ
admet-1885	119	2	dilutions	dilution	NOUN
admet-1885	119	3	were	be	AUX
admet-1885	119	4	made	make	VERB
admet-1885	119	5	after	after	ADP
admet-1885	119	6	filtration	filtration	NOUN
admet-1885	119	7	and	and	CCONJ
admet-1885	119	8	then	then	ADV
admet-1885	119	9	read	read	VERB
admet-1885	119	10	spectrophotometrically	spectrophotometrically	ADV
admet-1885	119	11	at	at	ADP
admet-1885	119	12	278	278	NUM
admet-1885	119	13	nm	nm	NOUN
admet-1885	119	14	.	.	PUNCT
admet-1885	120	1	phase	phase	NOUN
admet-1885	120	2	solubility	solubility	NOUN
admet-1885	120	3	study	study	VERB
admet-1885	120	4	a	a	DET
admet-1885	120	5	solubility	solubility	NOUN
admet-1885	120	6	study	study	NOUN
admet-1885	120	7	was	be	AUX
admet-1885	120	8	conducted	conduct	VERB
admet-1885	120	9	in	in	ADP
admet-1885	120	10	distilled	distil	VERB
admet-1885	120	11	water	water	NOUN
admet-1885	120	12	with	with	ADP
admet-1885	120	13	the	the	DET
admet-1885	120	14	higuchi	higuchi	PROPN
admet-1885	120	15	and	and	CCONJ
admet-1885	120	16	connors	connor	NOUN
admet-1885	120	17	method	method	NOUN
admet-1885	120	18	[	[	X
admet-1885	120	19	18	18	NUM
admet-1885	120	20	]	]	PUNCT
admet-1885	120	21	.	.	PUNCT
admet-1885	121	1	different	different	ADJ
admet-1885	121	2	amounts	amount	NOUN
admet-1885	121	3	of	of	ADP
admet-1885	121	4	hpβcd	hpβcd	INTJ
admet-1885	121	5	(	(	PUNCT
admet-1885	121	6	depending	depend	VERB
admet-1885	121	7	on	on	ADP
admet-1885	121	8	the	the	DET
admet-1885	121	9	results	result	NOUN
admet-1885	121	10	of	of	ADP
admet-1885	121	11	characterization	characterization	NOUN
admet-1885	121	12	)	)	PUNCT
admet-1885	121	13	were	be	AUX
admet-1885	121	14	dissolved	dissolve	VERB
admet-1885	121	15	in	in	ADP
admet-1885	121	16	20	20	NUM
admet-1885	121	17	ml	ml	NOUN
admet-1885	121	18	distilled	distil	VERB
admet-1885	121	19	water	water	NOUN
admet-1885	121	20	and	and	CCONJ
admet-1885	121	21	the	the	DET
admet-1885	121	22	excess	excess	ADJ
admet-1885	121	23	amount	amount	NOUN
admet-1885	121	24	of	of	ADP
admet-1885	121	25	ap	ap	PROPN
admet-1885	121	26	was	be	AUX
admet-1885	121	27	added	add	VERB
admet-1885	121	28	.	.	PUNCT
admet-1885	122	1	samples	sample	NOUN
admet-1885	122	2	were	be	AUX
admet-1885	122	3	placed	place	VERB
admet-1885	122	4	in	in	ADP
admet-1885	122	5	a	a	DET
admet-1885	122	6	water	water	NOUN
admet-1885	122	7	bath	bath	NOUN
admet-1885	122	8	at	at	ADP
admet-1885	122	9	25	25	NUM
admet-1885	122	10	°	°	NOUN
admet-1885	122	11	c	c	NOUN
admet-1885	122	12	for	for	ADP
admet-1885	122	13	24	24	NUM
admet-1885	122	14	hours	hour	NOUN
admet-1885	122	15	with	with	ADP
admet-1885	122	16	agitation	agitation	NOUN
admet-1885	122	17	at	at	ADP
admet-1885	122	18	a	a	DET
admet-1885	122	19	rate	rate	NOUN
admet-1885	122	20	of	of	ADP
admet-1885	122	21	50	50	NUM
admet-1885	122	22	rpm	rpm	NOUN
admet-1885	122	23	until	until	SCONJ
admet-1885	122	24	equilibrium	equilibrium	NOUN
admet-1885	122	25	was	be	AUX
admet-1885	122	26	achieved	achieve	VERB
admet-1885	122	27	.	.	PUNCT
admet-1885	123	1	samples	sample	NOUN
admet-1885	123	2	of	of	ADP
admet-1885	123	3	3	3	NUM
admet-1885	123	4	ml	ml	NOUN
admet-1885	123	5	were	be	AUX
admet-1885	123	6	withdrawn	withdraw	VERB
admet-1885	123	7	and	and	CCONJ
admet-1885	123	8	filtered	filter	VERB
admet-1885	123	9	through	through	ADP
admet-1885	123	10	a	a	DET
admet-1885	123	11	0.45	0.45	NUM
admet-1885	123	12	μm	μm	NOUN
admet-1885	123	13	membrane	membrane	NOUN
admet-1885	123	14	filter	filter	NOUN
admet-1885	123	15	.	.	PUNCT
admet-1885	124	1	filtrate	filtrate	NOUN
admet-1885	124	2	(	(	PUNCT
admet-1885	124	3	100	100	NUM
admet-1885	124	4	μl	μl	PRON
admet-1885	124	5	)	)	PUNCT
admet-1885	124	6	was	be	AUX
admet-1885	124	7	diluted	dilute	VERB
admet-1885	124	8	appropriately	appropriately	ADV
admet-1885	124	9	and	and	CCONJ
admet-1885	124	10	assayed	assayed	ADJ
admet-1885	124	11	at	at	ADP
admet-1885	124	12	278	278	NUM
admet-1885	124	13	nm	nm	NOUN
admet-1885	124	14	.	.	PUNCT
admet-1885	125	1	the	the	DET
admet-1885	125	2	concentrations	concentration	NOUN
admet-1885	125	3	used	use	VERB
admet-1885	125	4	are	be	AUX
admet-1885	125	5	given	give	VERB
admet-1885	125	6	in	in	ADP
admet-1885	125	7	table	table	NOUN
admet-1885	125	8	1	1	NUM
admet-1885	125	9	.	.	PUNCT
admet-1885	125	10	table	table	NOUN
admet-1885	125	11	1	1	NUM
admet-1885	125	12	.	.	PUNCT
admet-1885	125	13	concentrations	concentration	NOUN
admet-1885	125	14	of	of	ADP
admet-1885	125	15	ap	ap	PROPN
admet-1885	125	16	(	(	PUNCT
admet-1885	125	17	using	use	VERB
admet-1885	125	18	excess	excess	ADJ
admet-1885	125	19	amount	amount	NOUN
admet-1885	125	20	)	)	PUNCT
admet-1885	125	21	and	and	CCONJ
admet-1885	125	22	hpβcd	hpβcd	INTJ
admet-1885	125	23	used	use	VERB
admet-1885	125	24	in	in	ADP
admet-1885	125	25	phase	phase	NOUN
admet-1885	125	26	solubility	solubility	NOUN
admet-1885	125	27	study	study	NOUN
admet-1885	125	28	.	.	PUNCT
admet-1885	126	1	sample	sample	NOUN
admet-1885	126	2	code	code	NOUN
admet-1885	126	3	chpβcd	chpβcd	PROPN
admet-1885	126	4	/	/	SYM
admet-1885	126	5	mmol	mmol	NOUN
admet-1885	126	6	l-1	l-1	NOUN
admet-1885	126	7	sample	sample	NOUN
admet-1885	126	8	1	1	NUM
admet-1885	126	9	4.00	4.00	NUM
admet-1885	126	10	sample	sample	NOUN
admet-1885	126	11	2	2	NUM
admet-1885	126	12	10.0	10.0	NUM
admet-1885	126	13	sample	sample	NOUN
admet-1885	126	14	3	3	NUM
admet-1885	126	15	15.0	15.0	NUM
admet-1885	126	16	sample	sample	NOUN
admet-1885	126	17	4	4	NUM
admet-1885	126	18	20.0	20.0	NUM
admet-1885	126	19	the	the	DET
admet-1885	126	20	solubility	solubility	NOUN
admet-1885	126	21	of	of	ADP
admet-1885	126	22	pure	pure	ADJ
admet-1885	126	23	ap	ap	PROPN
admet-1885	126	24	was	be	AUX
admet-1885	126	25	also	also	ADV
admet-1885	126	26	tested	test	VERB
admet-1885	126	27	using	use	VERB
admet-1885	126	28	distilled	distil	VERB
admet-1885	126	29	water	water	NOUN
admet-1885	126	30	and	and	CCONJ
admet-1885	126	31	an	an	DET
admet-1885	126	32	excess	excess	NOUN
admet-1885	126	33	of	of	ADP
admet-1885	126	34	ap	ap	PROPN
admet-1885	126	35	in	in	ADP
admet-1885	126	36	the	the	DET
admet-1885	126	37	same	same	ADJ
admet-1885	126	38	conditions	condition	NOUN
admet-1885	126	39	.	.	PUNCT
admet-1885	127	1	a	a	DET
admet-1885	127	2	phase	phase	NOUN
admet-1885	127	3	solubility	solubility	NOUN
admet-1885	127	4	graph	graph	NOUN
admet-1885	127	5	was	be	AUX
admet-1885	127	6	then	then	ADV
admet-1885	127	7	constructed	construct	VERB
admet-1885	127	8	,	,	PUNCT
admet-1885	127	9	and	and	CCONJ
admet-1885	127	10	the	the	DET
admet-1885	127	11	apparent	apparent	ADJ
admet-1885	127	12	stability	stability	NOUN
admet-1885	127	13	constants	constant	NOUN
admet-1885	127	14	(	(	PUNCT
admet-1885	127	15	kst	kst	PROPN
admet-1885	127	16	)	)	PUNCT
admet-1885	127	17	were	be	AUX
admet-1885	127	18	determined	determine	VERB
admet-1885	127	19	from	from	ADP
admet-1885	127	20	the	the	DET
admet-1885	127	21	phase	phase	NOUN
admet-1885	127	22	solubility	solubility	NOUN
admet-1885	127	23	analysis	analysis	NOUN
admet-1885	127	24	graph	graph	NOUN
admet-1885	127	25	using	use	VERB
admet-1885	127	26	equation	equation	NOUN
admet-1885	127	27	(	(	PUNCT
admet-1885	127	28	3	3	NUM
admet-1885	127	29	):	):	PUNCT
admet-1885	127	30	kst	kst	PROPN
admet-1885	127	31	=	=	SYM
admet-1885	127	32	slope/	slope/	PROPN
admet-1885	127	33	(	(	PUNCT
admet-1885	127	34	s0	s0	X
admet-1885	127	35	(	(	PUNCT
admet-1885	127	36	1	1	NUM
admet-1885	127	37	slope	slope	NOUN
admet-1885	127	38	)	)	PUNCT
admet-1885	127	39	)	)	PUNCT
admet-1885	127	40	(	(	PUNCT
admet-1885	127	41	3	3	X
admet-1885	127	42	)	)	PUNCT
admet-1885	127	43	where	where	SCONJ
admet-1885	127	44	kst	kst	PROPN
admet-1885	127	45	is	be	AUX
admet-1885	127	46	the	the	DET
admet-1885	127	47	stability	stability	NOUN
admet-1885	127	48	constant	constant	ADJ
admet-1885	127	49	of	of	ADP
admet-1885	127	50	the	the	DET
admet-1885	127	51	complex	complex	NOUN
admet-1885	127	52	,	,	PUNCT
admet-1885	127	53	s0	s0	PROPN
admet-1885	127	54	is	be	AUX
admet-1885	127	55	the	the	DET
admet-1885	127	56	absolute	absolute	ADJ
admet-1885	127	57	solubility	solubility	NOUN
admet-1885	127	58	of	of	ADP
admet-1885	127	59	ap	ap	PROPN
admet-1885	127	60	in	in	ADP
admet-1885	127	61	the	the	DET
admet-1885	127	62	absence	absence	NOUN
admet-1885	127	63	of	of	ADP
admet-1885	127	64	cds	cd	NOUN
admet-1885	128	1	[	[	X
admet-1885	128	2	18	18	NUM
admet-1885	128	3	]	]	SYM
admet-1885	128	4	.	.	PUNCT
admet-1885	128	5	https://doi.org/10.5599/admet.1885	https://doi.org/10.5599/admet.1885	PROPN
admet-1885	128	6	z.	z.	PROPN
admet-1885	128	7	n.	n.	PROPN
admet-1885	128	8	salman	salman	PROPN
admet-1885	128	9	et	et	PROPN
admet-1885	128	10	al	al	PROPN
admet-1885	128	11	.	.	PROPN
admet-1885	128	12	admet	admet	PROPN
admet-1885	128	13	&	&	CCONJ
admet-1885	128	14	dmpk	dmpk	PROPN
admet-1885	128	15	11(4	11(4	NUM
admet-1885	128	16	)	)	PUNCT
admet-1885	128	17	(	(	PUNCT
admet-1885	128	18	2023	2023	NUM
admet-1885	128	19	)	)	PUNCT
admet-1885	128	20	533	533	NUM
admet-1885	128	21	-	-	SYM
admet-1885	128	22	550	550	NUM
admet-1885	128	23	538	538	NUM
admet-1885	128	24	computer	computer	NOUN
admet-1885	128	25	simulation	simulation	NOUN
admet-1885	128	26	of	of	ADP
admet-1885	128	27	inclusion	inclusion	NOUN
admet-1885	128	28	complex	complex	NOUN
admet-1885	128	29	the	the	DET
admet-1885	128	30	structure	structure	NOUN
admet-1885	128	31	of	of	ADP
admet-1885	128	32	the	the	DET
admet-1885	128	33	guest	guest	NOUN
admet-1885	128	34	molecule	molecule	NOUN
admet-1885	128	35	,	,	PUNCT
admet-1885	128	36	ap	ap	PROPN
admet-1885	128	37	,	,	PUNCT
admet-1885	128	38	was	be	AUX
admet-1885	128	39	downloaded	download	VERB
admet-1885	128	40	as	as	ADP
admet-1885	128	41	a	a	DET
admet-1885	128	42	mol	mol	NOUN
admet-1885	128	43	file	file	NOUN
admet-1885	128	44	from	from	ADP
admet-1885	128	45	the	the	DET
admet-1885	128	46	chemspider	chemspider	NOUN
admet-1885	128	47	database	database	NOUN
admet-1885	128	48	(	(	PUNCT
admet-1885	128	49	www.chemspider.com	www.chemspider.com	X
admet-1885	128	50	)	)	PUNCT
admet-1885	129	1	[	[	X
admet-1885	129	2	19	19	NUM
admet-1885	129	3	]	]	PUNCT
admet-1885	129	4	.	.	PUNCT
admet-1885	130	1	the	the	DET
admet-1885	130	2	structure	structure	NOUN
admet-1885	130	3	was	be	AUX
admet-1885	130	4	optimized	optimize	VERB
admet-1885	130	5	using	use	VERB
admet-1885	130	6	the	the	DET
admet-1885	130	7	am1	am1	PROPN
admet-1885	130	8	method	method	NOUN
admet-1885	130	9	using	use	VERB
admet-1885	130	10	gaussian09	gaussian09	NOUN
admet-1885	130	11	software	software	NOUN
admet-1885	131	1	[	[	X
admet-1885	131	2	20	20	NUM
admet-1885	131	3	]	]	PUNCT
admet-1885	131	4	.	.	PUNCT
admet-1885	132	1	on	on	ADP
admet-1885	132	2	the	the	DET
admet-1885	132	3	other	other	ADJ
admet-1885	132	4	hand	hand	NOUN
admet-1885	132	5	,	,	PUNCT
admet-1885	132	6	the	the	DET
admet-1885	132	7	crystal	crystal	NOUN
admet-1885	132	8	structure	structure	NOUN
admet-1885	132	9	of	of	ADP
admet-1885	132	10	the	the	DET
admet-1885	132	11	host	host	NOUN
admet-1885	132	12	molecule	molecule	NOUN
admet-1885	132	13	βcd	βcd	CCONJ
admet-1885	132	14	was	be	AUX
admet-1885	132	15	downloaded	download	VERB
admet-1885	132	16	from	from	ADP
admet-1885	132	17	cambridge	cambridge	PROPN
admet-1885	132	18	crystallographic	crystallographic	PROPN
admet-1885	132	19	data	data	PROPN
admet-1885	132	20	centre	centre	PROPN
admet-1885	132	21	(	(	PUNCT
admet-1885	132	22	ccdc	ccdc	PROPN
admet-1885	132	23	)	)	PUNCT
admet-1885	132	24	under	under	ADP
admet-1885	132	25	the	the	DET
admet-1885	132	26	reference	reference	NOUN
admet-1885	132	27	number	number	NOUN
admet-1885	132	28	.	.	PUNCT
admet-1885	133	1	the	the	DET
admet-1885	133	2	structure	structure	NOUN
admet-1885	133	3	was	be	AUX
admet-1885	133	4	checked	check	VERB
admet-1885	133	5	,	,	PUNCT
admet-1885	133	6	and	and	CCONJ
admet-1885	133	7	the	the	DET
admet-1885	133	8	crystalized	crystalize	VERB
admet-1885	133	9	molecules	molecule	NOUN
admet-1885	133	10	were	be	AUX
admet-1885	133	11	removed	remove	VERB
admet-1885	133	12	.	.	PUNCT
admet-1885	134	1	in	in	ADP
admet-1885	134	2	addition	addition	NOUN
admet-1885	134	3	,	,	PUNCT
admet-1885	134	4	hydroxypropyl	hydroxypropyl	NOUN
admet-1885	134	5	groups	group	NOUN
admet-1885	134	6	were	be	AUX
admet-1885	134	7	added	add	VERB
admet-1885	134	8	using	use	VERB
admet-1885	134	9	gaussview	gaussview	NOUN
admet-1885	134	10	[	[	PUNCT
admet-1885	134	11	20	20	NUM
admet-1885	134	12	]	]	PUNCT
admet-1885	134	13	to	to	PART
admet-1885	134	14	produce	produce	VERB
admet-1885	134	15	the	the	DET
admet-1885	134	16	hydroxypropyl	hydroxypropyl	NOUN
admet-1885	134	17	-	-	PUNCT
admet-1885	134	18	βcd	βcd	NUM
admet-1885	134	19	structure	structure	NOUN
admet-1885	134	20	.	.	PUNCT
admet-1885	135	1	the	the	DET
admet-1885	135	2	optimized	optimize	VERB
admet-1885	135	3	structure	structure	NOUN
admet-1885	135	4	of	of	ADP
admet-1885	135	5	the	the	DET
admet-1885	135	6	guest	guest	NOUN
admet-1885	135	7	molecule	molecule	NOUN
admet-1885	135	8	was	be	AUX
admet-1885	135	9	then	then	ADV
admet-1885	135	10	docked	dock	VERB
admet-1885	135	11	at	at	ADP
admet-1885	135	12	the	the	DET
admet-1885	135	13	center	center	NOUN
admet-1885	135	14	of	of	ADP
admet-1885	135	15	the	the	DET
admet-1885	135	16	host	host	NOUN
admet-1885	135	17	molecules	molecule	NOUN
admet-1885	135	18	,	,	PUNCT
admet-1885	135	19	βcd	βcd	NOUN
admet-1885	135	20	and	and	CCONJ
admet-1885	135	21	hpβcd	hpβcd	ADJ
admet-1885	135	22	.	.	PUNCT
admet-1885	136	1	to	to	PART
admet-1885	136	2	prepare	prepare	VERB
admet-1885	136	3	the	the	DET
admet-1885	136	4	host	host	NOUN
admet-1885	136	5	-	-	PUNCT
admet-1885	136	6	guest	guest	NOUN
admet-1885	136	7	complexes	complex	NOUN
admet-1885	136	8	for	for	ADP
admet-1885	136	9	docking	docking	NOUN
admet-1885	136	10	calculations	calculation	NOUN
admet-1885	136	11	,	,	PUNCT
admet-1885	136	12	kollman	kollman	PROPN
admet-1885	136	13	united	united	PROPN
admet-1885	136	14	atom	atom	PROPN
admet-1885	136	15	(	(	PUNCT
admet-1885	136	16	kua	kua	PROPN
admet-1885	136	17	)	)	PUNCT
admet-1885	136	18	charges	charge	NOUN
admet-1885	136	19	were	be	AUX
admet-1885	136	20	added	add	VERB
admet-1885	136	21	in	in	ADP
admet-1885	136	22	a	a	DET
admet-1885	136	23	grid	grid	NOUN
admet-1885	136	24	box	box	NOUN
admet-1885	136	25	with	with	ADP
admet-1885	136	26	60x60x60	60x60x60	NUM
admet-1885	136	27	dimensions	dimension	NOUN
admet-1885	136	28	using	use	VERB
admet-1885	136	29	autogrid	autogrid	NOUN
admet-1885	136	30	as	as	ADP
admet-1885	136	31	part	part	NOUN
admet-1885	136	32	of	of	ADP
admet-1885	136	33	autodock	autodock	NOUN
admet-1885	136	34	4	4	NUM
admet-1885	136	35	software	software	NOUN
admet-1885	136	36	(	(	PUNCT
admet-1885	136	37	molinspiration	molinspiration	NOUN
admet-1885	136	38	database	database	NOUN
admet-1885	136	39	)	)	PUNCT
admet-1885	136	40	.	.	PUNCT
admet-1885	137	1	all	all	DET
admet-1885	137	2	possible	possible	ADJ
admet-1885	137	3	conformations	conformation	NOUN
admet-1885	137	4	were	be	AUX
admet-1885	137	5	docked	dock	VERB
admet-1885	137	6	at	at	ADP
admet-1885	137	7	the	the	DET
admet-1885	137	8	center	center	NOUN
admet-1885	137	9	of	of	ADP
admet-1885	137	10	the	the	DET
admet-1885	137	11	host	host	NOUN
admet-1885	137	12	molecule	molecule	NOUN
admet-1885	137	13	using	use	VERB
admet-1885	137	14	the	the	DET
admet-1885	137	15	lamarckian	lamarckian	ADJ
admet-1885	137	16	genetic	genetic	ADJ
admet-1885	137	17	algorithm	algorithm	NOUN
admet-1885	137	18	with	with	ADP
admet-1885	137	19	250	250	NUM
admet-1885	137	20	runs	run	NOUN
admet-1885	137	21	for	for	ADP
admet-1885	137	22	each	each	DET
admet-1885	137	23	guest	guest	NOUN
admet-1885	137	24	molecule	molecule	NOUN
admet-1885	137	25	.	.	PUNCT
admet-1885	138	1	in	in	ADP
admet-1885	138	2	vitro	vitro	X
admet-1885	138	3	dissolution	dissolution	NOUN
admet-1885	138	4	of	of	ADP
admet-1885	138	5	ap	ap	PROPN
admet-1885	138	6	-	-	PUNCT
admet-1885	138	7	hpβcds	hpβcds	NOUN
admet-1885	138	8	inclusion	inclusion	NOUN
admet-1885	138	9	complexes	complex	NOUN
admet-1885	138	10	versus	versus	ADP
admet-1885	138	11	free	free	PROPN
admet-1885	138	12	ap	ap	PROPN
admet-1885	138	13	powder	powder	NOUN
admet-1885	138	14	dissolution	dissolution	NOUN
admet-1885	138	15	was	be	AUX
admet-1885	138	16	performed	perform	VERB
admet-1885	138	17	to	to	PART
admet-1885	138	18	compare	compare	VERB
admet-1885	138	19	the	the	DET
admet-1885	138	20	dissolution	dissolution	NOUN
admet-1885	138	21	of	of	ADP
admet-1885	138	22	free	free	PROPN
admet-1885	138	23	ap	ap	PROPN
admet-1885	138	24	with	with	ADP
admet-1885	138	25	the	the	DET
admet-1885	138	26	complex	complex	NOUN
admet-1885	138	27	prepared	prepare	VERB
admet-1885	138	28	in	in	ADP
admet-1885	138	29	a	a	DET
admet-1885	138	30	dissolution	dissolution	NOUN
admet-1885	138	31	apparatus	apparatus	NOUN
admet-1885	138	32	usp	usp	NOUN
admet-1885	138	33	type	type	PROPN
admet-1885	138	34	ii	ii	PROPN
admet-1885	138	35	(	(	PUNCT
admet-1885	138	36	paddle	paddle	NOUN
admet-1885	138	37	type	type	NOUN
admet-1885	138	38	)	)	PUNCT
admet-1885	138	39	.	.	PUNCT
admet-1885	139	1	the	the	DET
admet-1885	139	2	dissolution	dissolution	ADJ
admet-1885	139	3	medium	medium	NOUN
admet-1885	139	4	consists	consist	VERB
admet-1885	139	5	of	of	ADP
admet-1885	139	6	900	900	NUM
admet-1885	139	7	ml	ml	NOUN
admet-1885	139	8	(	(	PUNCT
admet-1885	139	9	ph	ph	ADJ
admet-1885	139	10	6.8	6.8	NUM
admet-1885	139	11	phosphate	phosphate	NOUN
admet-1885	139	12	buffer	buffer	NOUN
admet-1885	139	13	)	)	PUNCT
admet-1885	139	14	maintained	maintain	VERB
admet-1885	139	15	at	at	ADP
admet-1885	139	16	37±1	37±1	PROPN
admet-1885	139	17	°	°	ADP
admet-1885	139	18	c	c	PROPN
admet-1885	139	19	,	,	PUNCT
admet-1885	139	20	with	with	ADP
admet-1885	139	21	paddle	paddle	NOUN
admet-1885	139	22	rotation	rotation	NOUN
admet-1885	139	23	at	at	ADP
admet-1885	139	24	the	the	DET
admet-1885	139	25	speed	speed	NOUN
admet-1885	139	26	of	of	ADP
admet-1885	139	27	50	50	NUM
admet-1885	139	28	rpm	rpm	NOUN
admet-1885	139	29	.	.	PUNCT
admet-1885	140	1	three	three	NUM
admet-1885	140	2	jars	jar	NOUN
admet-1885	140	3	were	be	AUX
admet-1885	140	4	used	use	VERB
admet-1885	140	5	for	for	ADP
admet-1885	140	6	free	free	ADJ
admet-1885	140	7	drug	drug	NOUN
admet-1885	140	8	and	and	CCONJ
admet-1885	140	9	3	3	NUM
admet-1885	140	10	jars	jar	NOUN
admet-1885	140	11	for	for	ADP
admet-1885	140	12	the	the	DET
admet-1885	140	13	complex	complex	NOUN
admet-1885	140	14	.	.	PUNCT
admet-1885	141	1	five	five	NUM
admet-1885	141	2	mg	mg	PROPN
admet-1885	141	3	ap	ap	PROPN
admet-1885	141	4	free	free	ADJ
admet-1885	141	5	was	be	AUX
admet-1885	141	6	added	add	VERB
admet-1885	141	7	in	in	ADP
admet-1885	141	8	each	each	DET
admet-1885	141	9	jar	jar	NOUN
admet-1885	141	10	specified	specify	VERB
admet-1885	141	11	for	for	ADP
admet-1885	141	12	“	"	PUNCT
admet-1885	141	13	free	free	ADJ
admet-1885	141	14	drug	drug	NOUN
admet-1885	141	15	”	"	PUNCT
admet-1885	141	16	and	and	CCONJ
admet-1885	141	17	an	an	DET
admet-1885	141	18	amount	amount	NOUN
admet-1885	141	19	of	of	ADP
admet-1885	141	20	the	the	DET
admet-1885	141	21	dry	dry	ADJ
admet-1885	141	22	complex	complex	ADJ
admet-1885	141	23	powder	powder	NOUN
admet-1885	141	24	equivalent	equivalent	ADJ
admet-1885	141	25	to	to	ADP
admet-1885	141	26	5	5	NUM
admet-1885	141	27	mg	mg	PROPN
admet-1885	141	28	ap	ap	PROPN
admet-1885	141	29	was	be	AUX
admet-1885	141	30	added	add	VERB
admet-1885	141	31	to	to	ADP
admet-1885	141	32	the	the	DET
admet-1885	141	33	jars	jar	NOUN
admet-1885	141	34	specified	specify	VERB
admet-1885	141	35	to	to	ADP
admet-1885	141	36	the	the	DET
admet-1885	141	37	“	"	PUNCT
admet-1885	141	38	complex	complex	ADJ
admet-1885	141	39	powder	powder	NOUN
admet-1885	141	40	”	"	PUNCT
admet-1885	141	41	and	and	CCONJ
admet-1885	141	42	labeled	label	VERB
admet-1885	141	43	.	.	PUNCT
admet-1885	142	1	samples	sample	NOUN
admet-1885	142	2	of	of	ADP
admet-1885	142	3	5	5	NUM
admet-1885	142	4	ml	ml	NOUN
admet-1885	142	5	dissolution	dissolution	ADJ
admet-1885	142	6	media	medium	NOUN
admet-1885	142	7	were	be	AUX
admet-1885	142	8	withdrawn	withdraw	VERB
admet-1885	142	9	at	at	ADP
admet-1885	142	10	various	various	ADJ
admet-1885	142	11	time	time	NOUN
admet-1885	142	12	points	point	NOUN
admet-1885	142	13	and	and	CCONJ
admet-1885	142	14	replaced	replace	VERB
admet-1885	142	15	with	with	ADP
admet-1885	142	16	fresh	fresh	ADJ
admet-1885	142	17	buffer	buffer	NOUN
admet-1885	142	18	at	at	ADP
admet-1885	142	19	time	time	NOUN
admet-1885	142	20	points	point	NOUN
admet-1885	142	21	:	:	PUNCT
admet-1885	142	22	5	5	NUM
admet-1885	142	23	,	,	PUNCT
admet-1885	142	24	10	10	NUM
admet-1885	142	25	,	,	PUNCT
admet-1885	142	26	20	20	NUM
admet-1885	142	27	,	,	PUNCT
admet-1885	142	28	30	30	NUM
admet-1885	142	29	,	,	PUNCT
admet-1885	142	30	45	45	NUM
admet-1885	142	31	,	,	PUNCT
admet-1885	142	32	and	and	CCONJ
admet-1885	142	33	60	60	NUM
admet-1885	142	34	minutes	minute	NOUN
admet-1885	142	35	.	.	PUNCT
admet-1885	143	1	samples	sample	NOUN
admet-1885	143	2	were	be	AUX
admet-1885	143	3	analyzed	analyze	VERB
admet-1885	143	4	using	use	VERB
admet-1885	143	5	the	the	DET
admet-1885	143	6	validated	validate	VERB
admet-1885	143	7	method	method	NOUN
admet-1885	143	8	and	and	CCONJ
admet-1885	143	9	the	the	DET
admet-1885	143	10	percent	percent	NOUN
admet-1885	143	11	cumulative	cumulative	ADJ
admet-1885	143	12	ap	ap	PROPN
admet-1885	143	13	release	release	NOUN
admet-1885	143	14	versus	versus	ADP
admet-1885	143	15	time	time	NOUN
admet-1885	143	16	point	point	NOUN
admet-1885	143	17	were	be	AUX
admet-1885	143	18	calculated	calculate	VERB
admet-1885	143	19	and	and	CCONJ
admet-1885	143	20	plotted	plot	VERB
admet-1885	143	21	.	.	PUNCT
admet-1885	144	1	preparation	preparation	NOUN
admet-1885	144	2	of	of	ADP
admet-1885	144	3	ap	ap	PROPN
admet-1885	144	4	capsules	capsules	PROPN
admet-1885	144	5	ap	ap	PROPN
admet-1885	144	6	is	be	AUX
admet-1885	144	7	found	find	VERB
admet-1885	144	8	in	in	ADP
admet-1885	144	9	the	the	DET
admet-1885	144	10	market	market	NOUN
admet-1885	144	11	as	as	SCONJ
admet-1885	144	12	tablets	tablet	NOUN
admet-1885	144	13	contain	contain	VERB
admet-1885	144	14	2.5	2.5	NUM
admet-1885	144	15	or	or	CCONJ
admet-1885	144	16	5	5	NUM
admet-1885	144	17	mg	mg	NOUN
admet-1885	144	18	ap	ap	PROPN
admet-1885	144	19	and	and	CCONJ
admet-1885	144	20	(	(	PUNCT
admet-1885	144	21	anhydrous	anhydrous	ADJ
admet-1885	144	22	lactose	lactose	NOUN
admet-1885	144	23	(	(	PUNCT
admet-1885	144	24	bulking	bulking	NOUN
admet-1885	144	25	agent	agent	NOUN
admet-1885	144	26	)	)	PUNCT
admet-1885	144	27	)	)	PUNCT
admet-1885	144	28	,	,	PUNCT
admet-1885	144	29	microcrystalline	microcrystalline	NOUN
admet-1885	144	30	cellulose	cellulose	NOUN
admet-1885	144	31	(	(	PUNCT
admet-1885	144	32	bulking	bulking	NOUN
admet-1885	144	33	agent	agent	NOUN
admet-1885	144	34	)	)	PUNCT
admet-1885	144	35	,	,	PUNCT
admet-1885	144	36	croscarmellose	croscarmellose	ADJ
admet-1885	144	37	sodium	sodium	NOUN
admet-1885	144	38	(	(	PUNCT
admet-1885	144	39	disintegrant	disintegrant	NOUN
admet-1885	144	40	)	)	PUNCT
admet-1885	144	41	,	,	PUNCT
admet-1885	144	42	sodium	sodium	NOUN
admet-1885	144	43	lauryl	lauryl	NOUN
admet-1885	144	44	sulfate	sulfate	NOUN
admet-1885	144	45	(	(	PUNCT
admet-1885	144	46	surfactant	surfactant	NOUN
admet-1885	144	47	)	)	PUNCT
admet-1885	144	48	,	,	PUNCT
admet-1885	144	49	and	and	CCONJ
admet-1885	144	50	magnesium	magnesium	NOUN
admet-1885	144	51	stearate	stearate	NOUN
admet-1885	144	52	(	(	PUNCT
admet-1885	144	53	lubricant	lubricant	NOUN
admet-1885	144	54	)	)	PUNCT
admet-1885	145	1	[	[	X
admet-1885	145	2	21	21	NUM
admet-1885	145	3	]	]	PUNCT
admet-1885	145	4	.	.	PUNCT
admet-1885	146	1	formulation	formulation	NOUN
admet-1885	146	2	of	of	ADP
admet-1885	146	3	tablets	tablet	NOUN
admet-1885	146	4	and	and	CCONJ
admet-1885	146	5	their	their	PRON
admet-1885	146	6	parameters	parameter	NOUN
admet-1885	146	7	was	be	AUX
admet-1885	146	8	left	leave	VERB
admet-1885	146	9	as	as	ADP
admet-1885	146	10	future	future	ADJ
admet-1885	146	11	work	work	NOUN
admet-1885	146	12	.	.	PUNCT
admet-1885	147	1	a	a	DET
admet-1885	147	2	simple	simple	ADJ
admet-1885	147	3	capsule	capsule	NOUN
admet-1885	147	4	dosage	dosage	NOUN
admet-1885	147	5	form	form	NOUN
admet-1885	147	6	was	be	AUX
admet-1885	147	7	prepared	prepare	VERB
admet-1885	147	8	to	to	PART
admet-1885	147	9	compare	compare	VERB
admet-1885	147	10	a	a	DET
admet-1885	147	11	formulation	formulation	NOUN
admet-1885	147	12	and	and	CCONJ
admet-1885	147	13	perform	perform	VERB
admet-1885	147	14	drug	drug	NOUN
admet-1885	147	15	release	release	NOUN
admet-1885	147	16	on	on	ADP
admet-1885	147	17	a	a	DET
admet-1885	147	18	dosage	dosage	NOUN
admet-1885	147	19	form	form	NOUN
admet-1885	147	20	.	.	PUNCT
admet-1885	148	1	a	a	DET
admet-1885	148	2	simulated	simulated	ADJ
admet-1885	148	3	capsule	capsule	NOUN
admet-1885	148	4	containing	contain	VERB
admet-1885	148	5	5	5	NUM
admet-1885	148	6	mg	mg	NUM
admet-1885	148	7	ap	ap	PROPN
admet-1885	148	8	,	,	PUNCT
admet-1885	148	9	94	94	NUM
admet-1885	148	10	mg	mg	PROPN
admet-1885	148	11	avicel	avicel	PROPN
admet-1885	148	12	ph102	ph102	PROPN
admet-1885	148	13	,	,	PUNCT
admet-1885	148	14	and	and	CCONJ
admet-1885	148	15	1	1	NUM
admet-1885	148	16	mg	mg	PROPN
admet-1885	148	17	sls	sls	NOUN
admet-1885	148	18	in	in	ADP
admet-1885	148	19	each	each	DET
admet-1885	148	20	capsule	capsule	NOUN
admet-1885	148	21	was	be	AUX
admet-1885	148	22	prepared	prepare	VERB
admet-1885	148	23	.	.	PUNCT
admet-1885	149	1	no	no	DET
admet-1885	149	2	disintegrant	disintegrant	NOUN
admet-1885	149	3	or	or	CCONJ
admet-1885	149	4	lubricant	lubricant	NOUN
admet-1885	149	5	was	be	AUX
admet-1885	149	6	needed	need	VERB
admet-1885	149	7	.	.	PUNCT
admet-1885	150	1	each	each	DET
admet-1885	150	2	test	test	NOUN
admet-1885	150	3	capsule	capsule	NOUN
admet-1885	150	4	contained	contain	VERB
admet-1885	150	5	an	an	DET
admet-1885	150	6	amount	amount	NOUN
admet-1885	150	7	of	of	ADP
admet-1885	150	8	complex	complex	ADJ
admet-1885	150	9	equivalent	equivalent	NOUN
admet-1885	150	10	to	to	ADP
admet-1885	150	11	5	5	NUM
admet-1885	150	12	mg	mg	PROPN
admet-1885	150	13	ap	ap	PROPN
admet-1885	150	14	,	,	PUNCT
admet-1885	150	15	1	1	NUM
admet-1885	150	16	mg	mg	PROPN
admet-1885	150	17	sls	sls	PROPN
admet-1885	150	18	and	and	CCONJ
admet-1885	150	19	the	the	DET
admet-1885	150	20	weight	weight	NOUN
admet-1885	150	21	was	be	AUX
admet-1885	150	22	completed	complete	VERB
admet-1885	150	23	to	to	ADP
admet-1885	150	24	100	100	NUM
admet-1885	150	25	mg	mg	ADP
admet-1885	150	26	by	by	ADP
admet-1885	150	27	avicel	avicel	PROPN
admet-1885	150	28	.	.	PUNCT
admet-1885	151	1	a	a	DET
admet-1885	151	2	small	small	ADJ
admet-1885	151	3	batch	batch	NOUN
admet-1885	151	4	of	of	ADP
admet-1885	151	5	20	20	NUM
admet-1885	151	6	capsules	capsule	NOUN
admet-1885	151	7	was	be	AUX
admet-1885	151	8	prepared	prepare	VERB
admet-1885	151	9	by	by	ADP
admet-1885	151	10	mixing	mix	VERB
admet-1885	151	11	ingredients	ingredient	NOUN
admet-1885	151	12	and	and	CCONJ
admet-1885	151	13	filling	fill	VERB
admet-1885	151	14	in	in	ADP
admet-1885	151	15	a	a	DET
admet-1885	151	16	lab	lab	NOUN
admet-1885	151	17	-	-	PUNCT
admet-1885	151	18	scale	scale	NOUN
admet-1885	151	19	capsule	capsule	NOUN
admet-1885	151	20	filling	fill	VERB
admet-1885	151	21	machine	machine	NOUN
admet-1885	151	22	.	.	PUNCT
admet-1885	152	1	to	to	PART
admet-1885	152	2	ensure	ensure	VERB
admet-1885	152	3	uniformity	uniformity	NOUN
admet-1885	152	4	of	of	ADP
admet-1885	152	5	weight	weight	NOUN
admet-1885	152	6	,	,	PUNCT
admet-1885	152	7	capsules	capsule	NOUN
admet-1885	152	8	were	be	AUX
admet-1885	152	9	weighed	weigh	VERB
admet-1885	152	10	individually	individually	ADV
admet-1885	152	11	and	and	CCONJ
admet-1885	152	12	any	any	DET
admet-1885	152	13	capsule	capsule	NOUN
admet-1885	152	14	deviating	deviate	VERB
admet-1885	152	15	by	by	ADP
admet-1885	152	16	5	5	NUM
admet-1885	152	17	%	%	NOUN
admet-1885	152	18	and	and	CCONJ
admet-1885	152	19	more	more	ADJ
admet-1885	152	20	from	from	ADP
admet-1885	152	21	100	100	NUM
admet-1885	152	22	mg	mg	NOUN
admet-1885	152	23	was	be	AUX
admet-1885	152	24	excluded	exclude	VERB
admet-1885	152	25	.	.	PUNCT
admet-1885	153	1	dissolution	dissolution	PROPN
admet-1885	153	2	test	test	NOUN
admet-1885	153	3	of	of	ADP
admet-1885	153	4	ap	ap	PROPN
admet-1885	153	5	capsules	capsule	VERB
admet-1885	153	6	the	the	DET
admet-1885	153	7	dissolution	dissolution	NOUN
admet-1885	153	8	test	test	NOUN
admet-1885	153	9	was	be	AUX
admet-1885	153	10	performed	perform	VERB
admet-1885	153	11	on	on	ADP
admet-1885	153	12	the	the	DET
admet-1885	153	13	prepared	prepared	PROPN
admet-1885	153	14	ap	ap	PROPN
admet-1885	153	15	capsule	capsule	PROPN
admet-1885	153	16	and	and	CCONJ
admet-1885	153	17	the	the	DET
admet-1885	153	18	complex	complex	ADJ
admet-1885	153	19	-containing	-containing	ADJ
admet-1885	153	20	capsules	capsule	NOUN
admet-1885	153	21	in	in	ADP
admet-1885	153	22	the	the	DET
admet-1885	153	23	same	same	ADJ
admet-1885	153	24	conditions	condition	NOUN
admet-1885	153	25	as	as	ADP
admet-1885	153	26	the	the	DET
admet-1885	153	27	powder	powder	NOUN
admet-1885	153	28	dissolution	dissolution	NOUN
admet-1885	153	29	.	.	PUNCT
admet-1885	154	1	each	each	DET
admet-1885	154	2	sample	sample	NOUN
admet-1885	154	3	withdrawn	withdraw	VERB
admet-1885	154	4	was	be	AUX
admet-1885	154	5	filtered	filter	VERB
admet-1885	154	6	through	through	ADP
admet-1885	154	7	a	a	DET
admet-1885	154	8	nylon	nylon	NOUN
admet-1885	154	9	membrane	membrane	NOUN
admet-1885	154	10	filter	filter	NOUN
admet-1885	154	11	(	(	PUNCT
admet-1885	154	12	0.45	0.45	NUM
admet-1885	154	13	μm	μm	NUM
admet-1885	154	14	)	)	PUNCT
admet-1885	154	15	,	,	PUNCT
admet-1885	154	16	diluted	dilute	VERB
admet-1885	154	17	by	by	ADP
admet-1885	154	18	methanol	methanol	NOUN
admet-1885	154	19	(	(	PUNCT
admet-1885	154	20	blank	blank	NOUN
admet-1885	154	21	)	)	PUNCT
admet-1885	154	22	and	and	CCONJ
admet-1885	154	23	analyzed	analyze	VERB
admet-1885	154	24	using	use	VERB
admet-1885	154	25	uv	uv	NOUN
admet-1885	154	26	spectrophotometer	spectrophotometer	NOUN
admet-1885	154	27	at	at	ADP
admet-1885	154	28	278	278	NUM
admet-1885	154	29	nm	nm	NOUN
admet-1885	154	30	.	.	PUNCT
admet-1885	155	1	the	the	DET
admet-1885	155	2	percent	percent	NOUN
admet-1885	155	3	cumulative	cumulative	ADJ
admet-1885	155	4	of	of	ADP
admet-1885	155	5	ap	ap	PROPN
admet-1885	155	6	release	release	NOUN
admet-1885	155	7	of	of	ADP
admet-1885	155	8	each	each	DET
admet-1885	155	9	experiment	experiment	NOUN
admet-1885	155	10	were	be	AUX
admet-1885	155	11	calculated	calculate	VERB
admet-1885	155	12	and	and	CCONJ
admet-1885	155	13	plotted	plot	VERB
admet-1885	155	14	.	.	PUNCT
admet-1885	156	1	to	to	PART
admet-1885	156	2	investigate	investigate	VERB
admet-1885	156	3	the	the	DET
admet-1885	156	4	kinetic	kinetic	NOUN
admet-1885	156	5	of	of	ADP
admet-1885	156	6	drug	drug	NOUN
admet-1885	156	7	release	release	NOUN
admet-1885	156	8	,	,	PUNCT
admet-1885	156	9	several	several	ADJ
admet-1885	156	10	release	release	NOUN
admet-1885	156	11	models	model	NOUN
admet-1885	156	12	were	be	AUX
admet-1885	156	13	applied	apply	VERB
admet-1885	156	14	.	.	PUNCT
admet-1885	157	1	these	these	DET
admet-1885	157	2	models	model	NOUN
admet-1885	157	3	are	be	AUX
admet-1885	157	4	shown	show	VERB
admet-1885	157	5	in	in	ADP
admet-1885	157	6	table	table	NOUN
admet-1885	157	7	2	2	NUM
admet-1885	157	8	.	.	PUNCT
admet-1885	158	1	the	the	DET
admet-1885	158	2	aim	aim	NOUN
admet-1885	158	3	is	be	AUX
admet-1885	158	4	to	to	PART
admet-1885	158	5	get	get	VERB
admet-1885	158	6	a	a	DET
admet-1885	158	7	straight	straight	ADJ
admet-1885	158	8	line	line	NOUN
admet-1885	158	9	,	,	PUNCT
admet-1885	158	10	and	and	CCONJ
admet-1885	158	11	the	the	DET
admet-1885	158	12	highest	high	ADJ
admet-1885	158	13	correlation	correlation	NOUN
admet-1885	158	14	(	(	PUNCT
admet-1885	158	15	r2	r2	PROPN
admet-1885	158	16	)	)	PUNCT
admet-1885	158	17	would	would	AUX
admet-1885	158	18	be	be	AUX
admet-1885	158	19	considered	consider	VERB
admet-1885	158	20	the	the	DET
admet-1885	158	21	closest	close	ADJ
admet-1885	158	22	model	model	NOUN
admet-1885	158	23	.	.	PUNCT
admet-1885	159	1	all	all	DET
admet-1885	159	2	models	model	NOUN
admet-1885	159	3	were	be	AUX
admet-1885	159	4	fitted	fit	VERB
admet-1885	159	5	using	use	VERB
admet-1885	159	6	microsoft	microsoft	PROPN
admet-1885	159	7	excel	excel	PROPN
admet-1885	159	8	.	.	PUNCT
admet-1885	160	1	http://www.chemspider.com/	http://www.chemspider.com/	PROPN
admet-1885	160	2	admet	admet	PROPN
admet-1885	160	3	&	&	CCONJ
admet-1885	160	4	dmpk	dmpk	PROPN
admet-1885	160	5	11(4	11(4	NUM
admet-1885	160	6	)	)	PUNCT
admet-1885	160	7	(	(	PUNCT
admet-1885	160	8	2023	2023	NUM
admet-1885	160	9	)	)	PUNCT
admet-1885	160	10	533	533	NUM
admet-1885	160	11	-	-	SYM
admet-1885	160	12	550	550	NUM
admet-1885	160	13	enhancement	enhancement	NOUN
admet-1885	160	14	of	of	ADP
admet-1885	160	15	apixaban	apixaban	ADJ
admet-1885	160	16	solubility	solubility	NOUN
admet-1885	160	17	by	by	ADP
admet-1885	160	18	cyclodextrins	cyclodextrin	NOUN
admet-1885	160	19	doi	doi	PROPN
admet-1885	160	20	:	:	PUNCT
admet-1885	160	21	https://doi.org/10.5599/adme	https://doi.org/10.5599/adme	NOUN
admet-1885	160	22	t.1885	t.1885	NOUN
admet-1885	160	23	539	539	NUM
admet-1885	160	24	table	table	NOUN
admet-1885	160	25	2	2	NUM
admet-1885	160	26	.	.	PUNCT
admet-1885	160	27	kinetic	kinetic	NOUN
admet-1885	160	28	of	of	ADP
admet-1885	160	29	drug	drug	NOUN
admet-1885	160	30	release	release	NOUN
admet-1885	160	31	models	model	NOUN
admet-1885	160	32	tested	test	VERB
admet-1885	160	33	.	.	PUNCT
admet-1885	161	1	model	model	NOUN
admet-1885	161	2	name	name	PROPN
admet-1885	161	3	y	y	NOUN
admet-1885	161	4	-	-	PUNCT
admet-1885	161	5	axis	axis	NOUN
admet-1885	161	6	x	x	ADJ
admet-1885	161	7	-	-	ADJ
admet-1885	161	8	axis	axis	ADJ
admet-1885	161	9	zero	zero	NUM
admet-1885	161	10	-	-	PUNCT
admet-1885	161	11	order	order	NOUN
admet-1885	161	12	cumulative	cumulative	ADJ
admet-1885	161	13	amount	amount	NOUN
admet-1885	161	14	of	of	ADP
admet-1885	161	15	drug	drug	NOUN
admet-1885	161	16	release	release	NOUN
admet-1885	161	17	time	time	NOUN
admet-1885	161	18	first	first	ADJ
admet-1885	161	19	order	order	NOUN
admet-1885	161	20	log	log	NOUN
admet-1885	161	21	(	(	PUNCT
admet-1885	161	22	cumulative	cumulative	ADJ
admet-1885	161	23	amount	amount	NOUN
admet-1885	161	24	of	of	ADP
admet-1885	161	25	drug	drug	NOUN
admet-1885	161	26	remained	remain	VERB
admet-1885	161	27	)	)	PUNCT
admet-1885	161	28	time	time	NOUN
admet-1885	161	29	peppas	peppas	NOUN
admet-1885	161	30	model	model	NOUN
admet-1885	161	31	log	log	PROPN
admet-1885	161	32	(	(	PUNCT
admet-1885	161	33	cumulative	cumulative	ADJ
admet-1885	161	34	amount	amount	NOUN
admet-1885	161	35	of	of	ADP
admet-1885	161	36	drug	drug	NOUN
admet-1885	161	37	release	release	NOUN
admet-1885	161	38	)	)	PUNCT
admet-1885	161	39	log	log	NOUN
admet-1885	161	40	(	(	PUNCT
admet-1885	161	41	time	time	NOUN
admet-1885	161	42	)	)	PUNCT
admet-1885	161	43	higuchi	higuchi	PROPN
admet-1885	161	44	model	model	NOUN
admet-1885	161	45	cumulative	cumulative	ADJ
admet-1885	161	46	amount	amount	NOUN
admet-1885	161	47	of	of	ADP
admet-1885	161	48	drug	drug	NOUN
admet-1885	161	49	release	release	NOUN
admet-1885	161	50	time1/2	time1/2	PROPN
admet-1885	161	51	hixon	hixon	PROPN
admet-1885	161	52	crowel	crowel	PROPN
admet-1885	161	53	model	model	PROPN
admet-1885	161	54	w0	w0	PROPN
admet-1885	161	55	1/3	1/3	PROPN
admet-1885	161	56	–	–	PUNCT
admet-1885	161	57	wt	wt	NUM
admet-1885	161	58	1/3	1/3	NUM
admet-1885	161	59	*	*	PUNCT
admet-1885	161	60	time	time	NOUN
admet-1885	161	61	*	*	PUNCT
admet-1885	161	62	w0	w0	PROPN
admet-1885	161	63	is	be	AUX
admet-1885	161	64	initial	initial	ADJ
admet-1885	161	65	amount	amount	NOUN
admet-1885	161	66	,	,	PUNCT
admet-1885	161	67	wt	wt	PROPN
admet-1885	161	68	is	be	AUX
admet-1885	161	69	amount	amount	VERB
admet-1885	161	70	remaining	remain	VERB
admet-1885	161	71	statistical	statistical	ADJ
admet-1885	161	72	analysis	analysis	NOUN
admet-1885	161	73	statistical	statistical	ADJ
admet-1885	161	74	analysis	analysis	NOUN
admet-1885	161	75	was	be	AUX
admet-1885	161	76	used	use	VERB
admet-1885	161	77	in	in	ADP
admet-1885	161	78	this	this	DET
admet-1885	161	79	study	study	NOUN
admet-1885	161	80	.	.	PUNCT
admet-1885	162	1	for	for	ADP
admet-1885	162	2	the	the	DET
admet-1885	162	3	method	method	NOUN
admet-1885	162	4	of	of	ADP
admet-1885	162	5	analysis	analysis	NOUN
admet-1885	162	6	,	,	PUNCT
admet-1885	162	7	means	mean	NOUN
admet-1885	162	8	,	,	PUNCT
admet-1885	162	9	standard	standard	ADJ
admet-1885	162	10	deviations	deviation	NOUN
admet-1885	162	11	(	(	PUNCT
admet-1885	162	12	sd	sd	NOUN
admet-1885	162	13	)	)	PUNCT
admet-1885	162	14	,	,	PUNCT
admet-1885	162	15	coefficient	coefficient	NOUN
admet-1885	162	16	of	of	ADP
admet-1885	162	17	variation	variation	NOUN
admet-1885	162	18	(	(	PUNCT
admet-1885	162	19	cv	cv	NOUN
admet-1885	162	20	)	)	PUNCT
admet-1885	162	21	and	and	CCONJ
admet-1885	162	22	their	their	PRON
admet-1885	162	23	percentages	percentage	NOUN
admet-1885	162	24	were	be	AUX
admet-1885	162	25	all	all	PRON
admet-1885	162	26	used	use	VERB
admet-1885	162	27	.	.	PUNCT
admet-1885	163	1	determination	determination	NOUN
admet-1885	163	2	of	of	ADP
admet-1885	163	3	correlation	correlation	NOUN
admet-1885	163	4	coefficient	coefficient	NOUN
admet-1885	163	5	(	(	PUNCT
admet-1885	163	6	r2	r2	PROPN
admet-1885	163	7	)	)	PUNCT
admet-1885	163	8	was	be	AUX
admet-1885	163	9	also	also	ADV
admet-1885	163	10	used	use	VERB
admet-1885	163	11	.	.	PUNCT
admet-1885	164	1	in	in	ADP
admet-1885	164	2	terms	term	NOUN
admet-1885	164	3	of	of	ADP
admet-1885	164	4	dissolution	dissolution	NOUN
admet-1885	164	5	and	and	CCONJ
admet-1885	164	6	phase	phase	NOUN
admet-1885	164	7	solubility	solubility	NOUN
admet-1885	164	8	analysis	analysis	NOUN
admet-1885	164	9	study	study	NOUN
admet-1885	164	10	,	,	PUNCT
admet-1885	164	11	a	a	DET
admet-1885	164	12	t	t	NOUN
admet-1885	164	13	-	-	PUNCT
admet-1885	164	14	test	test	NOUN
admet-1885	164	15	was	be	AUX
admet-1885	164	16	used	use	VERB
admet-1885	164	17	to	to	PART
admet-1885	164	18	compare	compare	VERB
admet-1885	164	19	the	the	DET
admet-1885	164	20	target	target	NOUN
admet-1885	164	21	parameters	parameter	NOUN
admet-1885	164	22	of	of	ADP
admet-1885	164	23	both	both	DET
admet-1885	164	24	drugs	drug	NOUN
admet-1885	164	25	when	when	SCONJ
admet-1885	164	26	given	give	VERB
admet-1885	164	27	alone	alone	ADJ
admet-1885	164	28	and	and	CCONJ
admet-1885	164	29	in	in	ADP
admet-1885	164	30	combination	combination	NOUN
admet-1885	164	31	to	to	PART
admet-1885	164	32	test	test	VERB
admet-1885	164	33	if	if	SCONJ
admet-1885	164	34	any	any	DET
admet-1885	164	35	significant	significant	ADJ
admet-1885	164	36	difference	difference	NOUN
admet-1885	164	37	in	in	ADP
admet-1885	164	38	ci	ci	NOUN
admet-1885	164	39	5	5	NUM
admet-1885	164	40	%	%	NOUN
admet-1885	164	41	is	be	AUX
admet-1885	164	42	present	present	ADJ
admet-1885	164	43	.	.	PUNCT
admet-1885	165	1	the	the	DET
admet-1885	165	2	online	online	ADJ
admet-1885	165	3	“	"	PUNCT
admet-1885	165	4	graphpad	graphpad	NOUN
admet-1885	165	5	”	"	PUNCT
admet-1885	165	6	or	or	CCONJ
admet-1885	165	7	excel	excel	PROPN
admet-1885	165	8	software	software	NOUN
admet-1885	165	9	program	program	NOUN
admet-1885	165	10	was	be	AUX
admet-1885	165	11	used	use	VERB
admet-1885	165	12	for	for	ADP
admet-1885	165	13	this	this	DET
admet-1885	165	14	purpose	purpose	NOUN
admet-1885	165	15	.	.	PUNCT
admet-1885	166	1	results	result	NOUN
admet-1885	166	2	and	and	CCONJ
admet-1885	166	3	discussion	discussion	NOUN
admet-1885	166	4	method	method	NOUN
admet-1885	166	5	development	development	NOUN
admet-1885	166	6	and	and	CCONJ
admet-1885	166	7	validation	validation	NOUN
admet-1885	166	8	a	a	DET
admet-1885	166	9	sample	sample	NOUN
admet-1885	166	10	of	of	ADP
admet-1885	166	11	ap	ap	PROPN
admet-1885	166	12	was	be	AUX
admet-1885	166	13	scanned	scan	VERB
admet-1885	166	14	for	for	ADP
admet-1885	166	15	the	the	DET
admet-1885	166	16	determination	determination	NOUN
admet-1885	166	17	of	of	ADP
admet-1885	166	18	the	the	DET
admet-1885	166	19	λmax	λmax	NOUN
admet-1885	166	20	.	.	PUNCT
admet-1885	167	1	figure	figure	NOUN
admet-1885	167	2	2	2	NUM
admet-1885	167	3	shows	show	VERB
admet-1885	167	4	the	the	DET
admet-1885	167	5	scanning	scanning	NOUN
admet-1885	167	6	result	result	NOUN
admet-1885	167	7	of	of	ADP
admet-1885	167	8	a	a	DET
admet-1885	167	9	solution	solution	NOUN
admet-1885	167	10	containing	contain	VERB
admet-1885	167	11	50	50	NUM
admet-1885	167	12	µg	µg	NOUN
admet-1885	167	13	/	/	SYM
admet-1885	167	14	ml	ml	NOUN
admet-1885	167	15	ap	ap	NOUN
admet-1885	167	16	in	in	ADP
admet-1885	167	17	ethanol	ethanol	NOUN
admet-1885	167	18	.	.	PUNCT
admet-1885	168	1	the	the	DET
admet-1885	168	2	wavelength	wavelength	NOUN
admet-1885	168	3	of	of	ADP
admet-1885	168	4	278	278	NUM
admet-1885	168	5	nm	nm	NOUN
admet-1885	168	6	gave	give	VERB
admet-1885	168	7	the	the	DET
admet-1885	168	8	maximum	maximum	ADJ
admet-1885	168	9	absorbance	absorbance	NOUN
admet-1885	168	10	.	.	PUNCT
admet-1885	169	1	scanning	scanning	NOUN
admet-1885	169	2	of	of	ADP
admet-1885	169	3	ethanol	ethanol	NOUN
admet-1885	169	4	alone	alone	ADJ
admet-1885	169	5	and	and	CCONJ
admet-1885	169	6	different	different	ADJ
admet-1885	169	7	concentrations	concentration	NOUN
admet-1885	169	8	of	of	ADP
admet-1885	169	9	βcd	βcd	NOUN
admet-1885	169	10	and	and	CCONJ
admet-1885	169	11	hpβcd	hpβcd	PROPN
admet-1885	169	12	was	be	AUX
admet-1885	169	13	also	also	ADV
admet-1885	169	14	performed	perform	VERB
admet-1885	169	15	to	to	PART
admet-1885	169	16	ensure	ensure	VERB
admet-1885	169	17	the	the	DET
admet-1885	169	18	specificity	specificity	NOUN
admet-1885	169	19	of	of	ADP
admet-1885	169	20	the	the	DET
admet-1885	169	21	λmax	λmax	NOUN
admet-1885	169	22	chosen	choose	VERB
admet-1885	169	23	.	.	PUNCT
admet-1885	170	1	these	these	DET
admet-1885	170	2	results	result	NOUN
admet-1885	170	3	proved	prove	VERB
admet-1885	170	4	that	that	SCONJ
admet-1885	170	5	the	the	DET
admet-1885	170	6	solvent	solvent	NOUN
admet-1885	170	7	,	,	PUNCT
admet-1885	170	8	βcd	βcd	NOUN
admet-1885	170	9	,	,	PUNCT
admet-1885	170	10	and	and	CCONJ
admet-1885	170	11	hpβcd	hpβcd	PROPN
admet-1885	170	12	have	have	VERB
admet-1885	170	13	negligible	negligible	ADJ
admet-1885	170	14	absorbances	absorbance	NOUN
admet-1885	170	15	at	at	ADP
admet-1885	170	16	the	the	DET
admet-1885	170	17	selected	select	VERB
admet-1885	170	18	λmax	λmax	NOUN
admet-1885	170	19	of	of	ADP
admet-1885	170	20	ap	ap	PROPN
admet-1885	170	21	,	,	PUNCT
admet-1885	170	22	which	which	PRON
admet-1885	170	23	is	be	AUX
admet-1885	170	24	278	278	NUM
admet-1885	170	25	nm	nm	NOUN
admet-1885	170	26	(	(	PUNCT
admet-1885	170	27	data	datum	NOUN
admet-1885	170	28	are	be	AUX
admet-1885	170	29	not	not	PART
admet-1885	170	30	shown	show	VERB
admet-1885	170	31	)	)	PUNCT
admet-1885	170	32	.	.	PUNCT
admet-1885	171	1	this	this	DET
admet-1885	171	2	λmax	λmax	NOUN
admet-1885	171	3	was	be	AUX
admet-1885	171	4	selected	select	VERB
admet-1885	171	5	to	to	PART
admet-1885	171	6	continue	continue	VERB
admet-1885	171	7	validation	validation	NOUN
admet-1885	171	8	and	and	CCONJ
admet-1885	171	9	other	other	ADJ
admet-1885	171	10	measurements	measurement	NOUN
admet-1885	171	11	in	in	ADP
admet-1885	171	12	the	the	DET
admet-1885	171	13	work	work	NOUN
admet-1885	171	14	.	.	PUNCT
admet-1885	172	1	wavelenght	wavelenght	NOUN
admet-1885	172	2	,	,	PUNCT
admet-1885	172	3	nm	nm	PRON
admet-1885	172	4	figure	figure	NOUN
admet-1885	172	5	2	2	NUM
admet-1885	172	6	.	.	PUNCT
admet-1885	173	1	uv	uv	NOUN
admet-1885	173	2	scanning	scanning	NOUN
admet-1885	173	3	of	of	ADP
admet-1885	173	4	a	a	DET
admet-1885	173	5	solution	solution	NOUN
admet-1885	173	6	containing	contain	VERB
admet-1885	173	7	50	50	NUM
admet-1885	173	8	µg	µg	NOUN
admet-1885	173	9	/	/	SYM
admet-1885	173	10	ml	ml	NOUN
admet-1885	173	11	ap	ap	NOUN
admet-1885	173	12	in	in	ADP
admet-1885	173	13	ethanol	ethanol	NOUN
admet-1885	173	14	.	.	PUNCT
admet-1885	174	1	the	the	DET
admet-1885	174	2	wavelength	wavelength	NOUN
admet-1885	174	3	of	of	ADP
admet-1885	174	4	278	278	NUM
admet-1885	174	5	nm	nm	NOUN
admet-1885	174	6	exhibited	exhibit	VERB
admet-1885	174	7	the	the	DET
admet-1885	174	8	highest	high	ADJ
admet-1885	174	9	absorption	absorption	NOUN
admet-1885	174	10	.	.	PUNCT
admet-1885	175	1	method	method	PROPN
admet-1885	175	2	validation	validation	NOUN
admet-1885	175	3	the	the	DET
admet-1885	175	4	method	method	NOUN
admet-1885	175	5	validation	validation	NOUN
admet-1885	175	6	followed	follow	VERB
admet-1885	175	7	the	the	DET
admet-1885	175	8	ich	ich	NOUN
admet-1885	175	9	guidelines	guideline	NOUN
admet-1885	175	10	in	in	ADP
admet-1885	175	11	terms	term	NOUN
admet-1885	175	12	of	of	ADP
admet-1885	175	13	linearity	linearity	NOUN
admet-1885	175	14	,	,	PUNCT
admet-1885	175	15	precision	precision	NOUN
admet-1885	175	16	,	,	PUNCT
admet-1885	175	17	accuracy	accuracy	NOUN
admet-1885	175	18	,	,	PUNCT
admet-1885	175	19	recovery	recovery	NOUN
admet-1885	175	20	,	,	PUNCT
admet-1885	175	21	and	and	CCONJ
admet-1885	175	22	robustness	robustness	NOUN
admet-1885	175	23	.	.	PUNCT
admet-1885	176	1	https://doi.org/10.5599/admet.1885	https://doi.org/10.5599/admet.1885	PROPN
admet-1885	176	2	z.	z.	PROPN
admet-1885	176	3	n.	n.	PROPN
admet-1885	176	4	salman	salman	PROPN
admet-1885	176	5	et	et	PROPN
admet-1885	176	6	al	al	PROPN
admet-1885	176	7	.	.	PROPN
admet-1885	176	8	admet	admet	PROPN
admet-1885	176	9	&	&	CCONJ
admet-1885	176	10	dmpk	dmpk	PROPN
admet-1885	176	11	11(4	11(4	NUM
admet-1885	176	12	)	)	PUNCT
admet-1885	176	13	(	(	PUNCT
admet-1885	176	14	2023	2023	NUM
admet-1885	176	15	)	)	PUNCT
admet-1885	176	16	533	533	NUM
admet-1885	176	17	-	-	SYM
admet-1885	176	18	550	550	NUM
admet-1885	176	19	540	540	NUM
admet-1885	176	20	linear	linear	ADJ
admet-1885	176	21	regression	regression	NOUN
admet-1885	176	22	was	be	AUX
admet-1885	176	23	observed	observe	VERB
admet-1885	176	24	in	in	ADP
admet-1885	176	25	the	the	DET
admet-1885	176	26	concentrations	concentration	NOUN
admet-1885	176	27	range	range	NOUN
admet-1885	176	28	of	of	ADP
admet-1885	176	29	15	15	NUM
admet-1885	176	30	90	90	NUM
admet-1885	176	31	μg	μg	NOUN
admet-1885	176	32	/	/	SYM
admet-1885	176	33	ml	ml	PROPN
admet-1885	176	34	.	.	PUNCT
admet-1885	177	1	the	the	DET
admet-1885	177	2	correlation	correlation	NOUN
admet-1885	177	3	coefficient	coefficient	NOUN
admet-1885	177	4	for	for	ADP
admet-1885	177	5	the	the	DET
admet-1885	177	6	linearity	linearity	NOUN
admet-1885	177	7	test	test	NOUN
admet-1885	177	8	was	be	AUX
admet-1885	177	9	0.998	0.998	NUM
admet-1885	177	10	.	.	PUNCT
admet-1885	178	1	figure	figure	NOUN
admet-1885	178	2	3	3	NUM
admet-1885	178	3	shows	show	VERB
admet-1885	178	4	the	the	DET
admet-1885	178	5	linearity	linearity	NOUN
admet-1885	178	6	plot	plot	NOUN
admet-1885	178	7	of	of	ADP
admet-1885	178	8	ap	ap	PROPN
admet-1885	178	9	.	.	PUNCT
admet-1885	179	1	all	all	DET
admet-1885	179	2	tests	test	NOUN
admet-1885	179	3	used	use	VERB
admet-1885	179	4	in	in	ADP
admet-1885	179	5	the	the	DET
admet-1885	179	6	measurement	measurement	NOUN
admet-1885	179	7	of	of	ADP
admet-1885	179	8	ap	ap	PROPN
admet-1885	179	9	had	have	VERB
admet-1885	179	10	the	the	DET
admet-1885	179	11	target	target	NOUN
admet-1885	179	12	of	of	ADP
admet-1885	179	13	dilutions	dilution	NOUN
admet-1885	179	14	to	to	PART
admet-1885	179	15	produce	produce	VERB
admet-1885	179	16	concentrations	concentration	NOUN
admet-1885	179	17	within	within	ADP
admet-1885	179	18	this	this	DET
admet-1885	179	19	range	range	NOUN
admet-1885	179	20	of	of	ADP
admet-1885	179	21	15	15	NUM
admet-1885	179	22	90	90	NUM
admet-1885	179	23	µg	µg	NOUN
admet-1885	179	24	/	/	SYM
admet-1885	179	25	ml	ml	NOUN
admet-1885	179	26	to	to	PART
admet-1885	179	27	ensure	ensure	VERB
admet-1885	179	28	linearity	linearity	NOUN
admet-1885	179	29	of	of	ADP
admet-1885	179	30	readings	reading	NOUN
admet-1885	179	31	versus	versus	ADP
admet-1885	179	32	concentrations	concentration	NOUN
admet-1885	179	33	.	.	PUNCT
admet-1885	180	1	the	the	DET
admet-1885	180	2	back	back	ADJ
admet-1885	180	3	-	-	PUNCT
admet-1885	180	4	calculation	calculation	NOUN
admet-1885	180	5	gave	give	VERB
admet-1885	180	6	rsd	rsd	NOUN
admet-1885	180	7	0.24	0.24	NUM
admet-1885	180	8	-	-	SYM
admet-1885	180	9	2.66	2.66	NUM
admet-1885	180	10	%	%	NOUN
admet-1885	180	11	.	.	PUNCT
admet-1885	181	1	cap	cap	NOUN
admet-1885	181	2	/	/	SYM
admet-1885	181	3	g	g	PROPN
admet-1885	181	4	ml-1	ml-1	PRON
admet-1885	181	5	figure	figure	NOUN
admet-1885	181	6	3	3	NUM
admet-1885	181	7	.	.	PUNCT
admet-1885	182	1	the	the	DET
admet-1885	182	2	linearity	linearity	NOUN
admet-1885	182	3	plot	plot	NOUN
admet-1885	182	4	of	of	ADP
admet-1885	182	5	ap	ap	PROPN
admet-1885	182	6	shows	show	VERB
admet-1885	182	7	the	the	DET
admet-1885	182	8	linear	linear	ADJ
admet-1885	182	9	regression	regression	NOUN
admet-1885	182	10	equation	equation	NOUN
admet-1885	182	11	and	and	CCONJ
admet-1885	182	12	correlation	correlation	NOUN
admet-1885	182	13	coefficient	coefficient	NOUN
admet-1885	182	14	.	.	PUNCT
admet-1885	183	1	the	the	DET
admet-1885	183	2	precision	precision	NOUN
admet-1885	183	3	of	of	ADP
admet-1885	183	4	an	an	DET
admet-1885	183	5	analytical	analytical	ADJ
admet-1885	183	6	procedure	procedure	NOUN
admet-1885	183	7	expresses	express	VERB
admet-1885	183	8	the	the	DET
admet-1885	183	9	closeness	closeness	NOUN
admet-1885	183	10	of	of	ADP
admet-1885	183	11	agreement	agreement	NOUN
admet-1885	183	12	(	(	PUNCT
admet-1885	183	13	degree	degree	NOUN
admet-1885	183	14	of	of	ADP
admet-1885	183	15	scatter	scatter	NOUN
admet-1885	183	16	)	)	PUNCT
admet-1885	183	17	between	between	ADP
admet-1885	183	18	a	a	DET
admet-1885	183	19	series	series	NOUN
admet-1885	183	20	of	of	ADP
admet-1885	183	21	measurements	measurement	NOUN
admet-1885	183	22	obtained	obtain	VERB
admet-1885	183	23	from	from	ADP
admet-1885	183	24	multiple	multiple	ADJ
admet-1885	183	25	sampling	sampling	NOUN
admet-1885	183	26	of	of	ADP
admet-1885	183	27	the	the	DET
admet-1885	183	28	same	same	ADJ
admet-1885	183	29	homogeneous	homogeneous	ADJ
admet-1885	183	30	sample	sample	NOUN
admet-1885	183	31	under	under	ADP
admet-1885	183	32	the	the	DET
admet-1885	183	33	prescribed	prescribed	ADJ
admet-1885	183	34	condition	condition	NOUN
admet-1885	183	35	.	.	PUNCT
admet-1885	184	1	precision	precision	NOUN
admet-1885	184	2	is	be	AUX
admet-1885	184	3	measured	measure	VERB
admet-1885	184	4	by	by	ADP
admet-1885	184	5	the	the	DET
admet-1885	184	6	rsd	rsd	NOUN
admet-1885	184	7	of	of	ADP
admet-1885	184	8	a	a	DET
admet-1885	184	9	series	series	NOUN
admet-1885	184	10	of	of	ADP
admet-1885	184	11	readings	reading	NOUN
admet-1885	184	12	which	which	PRON
admet-1885	184	13	should	should	AUX
admet-1885	184	14	not	not	PART
admet-1885	184	15	exceed	exceed	VERB
admet-1885	184	16	2.0	2.0	NUM
admet-1885	184	17	%	%	NOUN
admet-1885	184	18	according	accord	VERB
admet-1885	184	19	to	to	ADP
admet-1885	184	20	the	the	DET
admet-1885	184	21	ich	ich	NOUN
admet-1885	184	22	guidelines	guideline	NOUN
admet-1885	184	23	.	.	PUNCT
admet-1885	185	1	while	while	SCONJ
admet-1885	185	2	accuracy	accuracy	NOUN
admet-1885	185	3	is	be	AUX
admet-1885	185	4	expressed	express	VERB
admet-1885	185	5	in	in	ADP
admet-1885	185	6	“	"	PUNCT
admet-1885	185	7	percent	percent	NOUN
admet-1885	185	8	”	"	PUNCT
admet-1885	185	9	measured	measure	VERB
admet-1885	185	10	concentration	concentration	NOUN
admet-1885	185	11	relative	relative	ADJ
admet-1885	185	12	to	to	ADP
admet-1885	185	13	the	the	DET
admet-1885	185	14	theoretical	theoretical	ADJ
admet-1885	185	15	concentration	concentration	NOUN
admet-1885	185	16	.	.	PUNCT
admet-1885	186	1	measurements	measurement	NOUN
admet-1885	186	2	were	be	AUX
admet-1885	186	3	made	make	VERB
admet-1885	186	4	over	over	ADP
admet-1885	186	5	2	2	NUM
admet-1885	186	6	days	day	NOUN
admet-1885	186	7	.	.	PUNCT
admet-1885	187	1	table	table	NOUN
admet-1885	187	2	3	3	NUM
admet-1885	187	3	shows	show	VERB
admet-1885	187	4	measurements	measurement	NOUN
admet-1885	187	5	at	at	ADP
admet-1885	187	6	day	day	NOUN
admet-1885	187	7	1	1	NUM
admet-1885	187	8	(	(	PUNCT
admet-1885	187	9	interday	interday	NOUN
admet-1885	187	10	precision	precision	NOUN
admet-1885	187	11	)	)	PUNCT
admet-1885	187	12	and	and	CCONJ
admet-1885	187	13	day	day	NOUN
admet-1885	187	14	2	2	NUM
admet-1885	187	15	(	(	PUNCT
admet-1885	187	16	intraday	intraday	NOUN
admet-1885	187	17	precision	precision	NOUN
admet-1885	187	18	)	)	PUNCT
admet-1885	187	19	of	of	ADP
admet-1885	187	20	ap	ap	PROPN
admet-1885	187	21	.	.	PUNCT
admet-1885	188	1	the	the	DET
admet-1885	188	2	rsd	rsd	NOUN
admet-1885	188	3	for	for	ADP
admet-1885	188	4	all	all	DET
admet-1885	188	5	readings	reading	NOUN
admet-1885	188	6	ranged	range	VERB
admet-1885	188	7	0.88	0.88	NUM
admet-1885	188	8	to	to	ADP
admet-1885	188	9	1.2	1.2	NUM
admet-1885	188	10	%	%	NOUN
admet-1885	188	11	,	,	PUNCT
admet-1885	188	12	which	which	PRON
admet-1885	188	13	complies	comply	VERB
admet-1885	188	14	with	with	ADP
admet-1885	188	15	the	the	DET
admet-1885	188	16	ich	ich	NOUN
admet-1885	188	17	.	.	PUNCT
admet-1885	189	1	the	the	DET
admet-1885	189	2	accuracy	accuracy	NOUN
admet-1885	189	3	or	or	CCONJ
admet-1885	189	4	recovery	recovery	NOUN
admet-1885	189	5	of	of	ADP
admet-1885	189	6	ap	ap	PROPN
admet-1885	189	7	from	from	ADP
admet-1885	189	8	the	the	DET
admet-1885	189	9	samples	sample	NOUN
admet-1885	189	10	ranged	range	VERB
admet-1885	189	11	between	between	ADP
admet-1885	189	12	96.4	96.4	NUM
admet-1885	189	13	to	to	PART
admet-1885	189	14	103.2	103.2	NUM
admet-1885	189	15	%	%	NOUN
admet-1885	189	16	,	,	PUNCT
admet-1885	189	17	knowing	know	VERB
admet-1885	189	18	that	that	SCONJ
admet-1885	189	19	90	90	NUM
admet-1885	189	20	to	to	PART
admet-1885	189	21	110	110	NUM
admet-1885	189	22	%	%	NOUN
admet-1885	189	23	is	be	AUX
admet-1885	189	24	accepted	accept	VERB
admet-1885	189	25	as	as	ADP
admet-1885	189	26	per	per	ADP
admet-1885	189	27	the	the	DET
admet-1885	189	28	ich	ich	NOUN
admet-1885	189	29	guidelines	guideline	NOUN
admet-1885	189	30	.	.	PUNCT
admet-1885	190	1	table	table	NOUN
admet-1885	190	2	3	3	NUM
admet-1885	190	3	.	.	PUNCT
admet-1885	190	4	results	result	NOUN
admet-1885	190	5	of	of	ADP
admet-1885	190	6	inter	inter	ADJ
admet-1885	190	7	and	and	CCONJ
admet-1885	190	8	intra	intra	ADJ
admet-1885	190	9	-	-	ADJ
admet-1885	190	10	day	day	NOUN
admet-1885	190	11	precision	precision	NOUN
admet-1885	190	12	and	and	CCONJ
admet-1885	190	13	accuracy	accuracy	NOUN
admet-1885	190	14	of	of	ADP
admet-1885	190	15	ap	ap	PROPN
admet-1885	190	16	.	.	PUNCT
admet-1885	191	1	sample	sample	NOUN
admet-1885	192	1	i	i	PROPN
admet-1885	192	2	d	d	PROPN
admet-1885	192	3	ctheoretical	ctheoretical	ADJ
admet-1885	192	4	/	/	PUNCT
admet-1885	192	5	µg	µg	VERB
admet-1885	192	6	ml-1	ml-1	DET
admet-1885	192	7	absorbance	absorbance	NOUN
admet-1885	192	8	(	(	PUNCT
admet-1885	192	9	average	average	NOUN
admet-1885	192	10	of	of	ADP
admet-1885	192	11	n=3	n=3	NOUN
admet-1885	192	12	)	)	PUNCT
admet-1885	192	13	cmeasured	cmeasure	VERB
admet-1885	192	14	/	/	PUNCT
admet-1885	192	15	µg	µg	VERB
admet-1885	192	16	ml-1	ml-1	ADV
admet-1885	192	17	accuracy	accuracy	NOUN
admet-1885	192	18	,	,	PUNCT
admet-1885	192	19	%	%	NOUN
admet-1885	192	20	rsd	rsd	NOUN
admet-1885	192	21	,	,	PUNCT
admet-1885	192	22	%	%	NOUN
admet-1885	192	23	day	day	NOUN
admet-1885	192	24	1	1	NUM
admet-1885	192	25	sample1	sample1	NOUN
admet-1885	192	26	50	50	NUM
admet-1885	192	27	0.471	0.471	NUM
admet-1885	192	28	49.28	49.28	NUM
admet-1885	192	29	98.6	98.6	NUM
admet-1885	192	30	1.2	1.2	NUM
admet-1885	192	31	sample2	sample2	NOUN
admet-1885	192	32	50	50	NUM
admet-1885	192	33	0.473	0.473	NUM
admet-1885	192	34	49.47	49.47	NUM
admet-1885	192	35	98.9	98.9	NUM
admet-1885	192	36	sample3	sample3	NOUN
admet-1885	192	37	50	50	NUM
admet-1885	192	38	0.459	0.459	NUM
admet-1885	192	39	48.17	48.17	NUM
admet-1885	192	40	96.4	96.4	NUM
admet-1885	192	41	sample4	sample4	NOUN
admet-1885	192	42	50	50	NUM
admet-1885	192	43	0.480	0.480	NUM
admet-1885	192	44	50.12	50.12	NUM
admet-1885	192	45	100.2	100.2	NUM
admet-1885	192	46	sample5	sample5	NOUN
admet-1885	192	47	50	50	NUM
admet-1885	192	48	0.472	0.472	NUM
admet-1885	192	49	49.37	49.37	NUM
admet-1885	192	50	98.8	98.8	NUM
admet-1885	192	51	sample6	sample6	NOUN
admet-1885	192	52	50	50	NUM
admet-1885	192	53	0.470	0.470	NUM
admet-1885	192	54	49.19	49.19	NUM
admet-1885	192	55	98.4	98.4	NUM
admet-1885	192	56	day	day	NOUN
admet-1885	192	57	2	2	NUM
admet-1885	192	58	sample1	sample1	NOUN
admet-1885	192	59	50	50	NUM
admet-1885	192	60	0.496	0.496	NUM
admet-1885	192	61	51.60	51.60	NUM
admet-1885	192	62	103.2	103.2	NUM
admet-1885	192	63	0.88	0.88	NUM
admet-1885	192	64	sample2	sample2	NOUN
admet-1885	192	65	50	50	NUM
admet-1885	192	66	0.481	0.481	NUM
admet-1885	192	67	50.21	50.21	NUM
admet-1885	192	68	100.4	100.4	NUM
admet-1885	192	69	sample3	sample3	PROPN
admet-1885	192	70	50	50	NUM
admet-1885	192	71	0.469	0.469	NUM
admet-1885	192	72	49.10	49.10	NUM
admet-1885	192	73	98.2	98.2	NUM
admet-1885	192	74	sample4	sample4	NOUN
admet-1885	192	75	50	50	NUM
admet-1885	192	76	0.488	0.488	NUM
admet-1885	192	77	50.86	50.86	NUM
admet-1885	192	78	101.7	101.7	NUM
admet-1885	192	79	sample5	sample5	NOUN
admet-1885	192	80	50	50	NUM
admet-1885	192	81	0.476	0.476	NUM
admet-1885	192	82	49.75	49.75	NUM
admet-1885	192	83	99.5	99.5	NUM
admet-1885	192	84	sample6	sample6	NOUN
admet-1885	192	85	50	50	NUM
admet-1885	192	86	0.471	0.471	NUM
admet-1885	192	87	49.28	49.28	NUM
admet-1885	192	88	98.6	98.6	NUM
admet-1885	192	89	the	the	DET
admet-1885	192	90	powder	powder	NOUN
admet-1885	192	91	mixture	mixture	NOUN
admet-1885	192	92	of	of	ADP
admet-1885	192	93	the	the	DET
admet-1885	192	94	test	test	NOUN
admet-1885	192	95	capsule	capsule	NOUN
admet-1885	192	96	of	of	ADP
admet-1885	192	97	ap	ap	PROPN
admet-1885	192	98	was	be	AUX
admet-1885	192	99	used	use	VERB
admet-1885	192	100	to	to	PART
admet-1885	192	101	test	test	VERB
admet-1885	192	102	the	the	DET
admet-1885	192	103	recovery	recovery	NOUN
admet-1885	192	104	of	of	ADP
admet-1885	192	105	the	the	DET
admet-1885	192	106	method	method	NOUN
admet-1885	192	107	.	.	PUNCT
admet-1885	193	1	the	the	DET
admet-1885	193	2	formula	formula	NOUN
admet-1885	193	3	contained	contain	VERB
admet-1885	193	4	ap	ap	PROPN
admet-1885	193	5	beside	beside	ADP
admet-1885	193	6	other	other	ADJ
admet-1885	193	7	excipients	excipient	NOUN
admet-1885	193	8	prepared	prepare	VERB
admet-1885	193	9	to	to	PART
admet-1885	193	10	compare	compare	VERB
admet-1885	193	11	the	the	DET
admet-1885	193	12	dissolution	dissolution	NOUN
admet-1885	193	13	rate	rate	NOUN
admet-1885	193	14	of	of	ADP
admet-1885	193	15	the	the	DET
admet-1885	193	16	capsule	capsule	NOUN
admet-1885	193	17	containing	contain	VERB
admet-1885	193	18	the	the	DET
admet-1885	193	19	complex	complex	NOUN
admet-1885	193	20	to	to	ADP
admet-1885	193	21	the	the	DET
admet-1885	193	22	mixture	mixture	NOUN
admet-1885	193	23	of	of	ADP
admet-1885	193	24	drug	drug	NOUN
admet-1885	193	25	and	and	CCONJ
admet-1885	193	26	excipients	excipient	NOUN
admet-1885	193	27	.	.	PUNCT
admet-1885	194	1	the	the	DET
admet-1885	194	2	recovery	recovery	NOUN
admet-1885	194	3	or	or	CCONJ
admet-1885	194	4	accuracy	accuracy	NOUN
admet-1885	194	5	of	of	ADP
admet-1885	194	6	the	the	DET
admet-1885	194	7	previous	previous	ADJ
admet-1885	194	8	test	test	NOUN
admet-1885	194	9	was	be	AUX
admet-1885	194	10	calculated	calculate	VERB
admet-1885	194	11	y	y	PROPN
admet-1885	194	12	=	=	PUNCT
admet-1885	194	13	0.001x	0.001x	PROPN
admet-1885	194	14	–	–	PUNCT
admet-1885	194	15	0.0171	0.0171	NUM
admet-1885	194	16	r2	r2	NOUN
admet-1885	194	17	=	=	SYM
admet-1885	194	18	0.9983	0.9983	NUM
admet-1885	194	19	admet	admet	PROPN
admet-1885	194	20	&	&	CCONJ
admet-1885	194	21	dmpk	dmpk	PROPN
admet-1885	194	22	11(4	11(4	NUM
admet-1885	194	23	)	)	PUNCT
admet-1885	194	24	(	(	PUNCT
admet-1885	194	25	2023	2023	NUM
admet-1885	194	26	)	)	PUNCT
admet-1885	194	27	533	533	NUM
admet-1885	194	28	-	-	SYM
admet-1885	194	29	550	550	NUM
admet-1885	194	30	enhancement	enhancement	NOUN
admet-1885	194	31	of	of	ADP
admet-1885	194	32	apixaban	apixaban	ADJ
admet-1885	194	33	solubility	solubility	NOUN
admet-1885	194	34	by	by	ADP
admet-1885	194	35	cyclodextrins	cyclodextrin	NOUN
admet-1885	194	36	doi	doi	PROPN
admet-1885	194	37	:	:	PUNCT
admet-1885	194	38	https://doi.org/10.5599/adme	https://doi.org/10.5599/adme	NOUN
admet-1885	194	39	t.1885	t.1885	ADP
admet-1885	194	40	541	541	NUM
admet-1885	194	41	on	on	ADP
admet-1885	194	42	the	the	DET
admet-1885	194	43	pure	pure	ADJ
admet-1885	194	44	ap	ap	PROPN
admet-1885	194	45	dissolved	dissolve	VERB
admet-1885	194	46	in	in	ADP
admet-1885	194	47	ethanol	ethanol	NOUN
admet-1885	194	48	samples	sample	NOUN
admet-1885	194	49	.	.	PUNCT
admet-1885	195	1	while	while	SCONJ
admet-1885	195	2	this	this	DET
admet-1885	195	3	test	test	NOUN
admet-1885	195	4	examines	examine	VERB
admet-1885	195	5	the	the	DET
admet-1885	195	6	ability	ability	NOUN
admet-1885	195	7	of	of	ADP
admet-1885	195	8	the	the	DET
admet-1885	195	9	method	method	NOUN
admet-1885	195	10	to	to	PART
admet-1885	195	11	quantify	quantify	VERB
admet-1885	195	12	ap	ap	PROPN
admet-1885	195	13	in	in	ADP
admet-1885	195	14	the	the	DET
admet-1885	195	15	powder	powder	NOUN
admet-1885	195	16	mixture	mixture	NOUN
admet-1885	195	17	of	of	ADP
admet-1885	195	18	the	the	DET
admet-1885	195	19	formula	formula	NOUN
admet-1885	195	20	.	.	PUNCT
admet-1885	196	1	this	this	PRON
admet-1885	196	2	necessitates	necessitate	VERB
admet-1885	196	3	high	high	ADJ
admet-1885	196	4	specificity	specificity	NOUN
admet-1885	196	5	to	to	ADP
admet-1885	196	6	the	the	DET
admet-1885	196	7	compound	compound	NOUN
admet-1885	196	8	and	and	CCONJ
admet-1885	196	9	negligible	negligible	ADJ
admet-1885	196	10	effect	effect	NOUN
admet-1885	196	11	of	of	ADP
admet-1885	196	12	excipients	excipient	NOUN
admet-1885	196	13	.	.	PUNCT
admet-1885	197	1	a	a	DET
admet-1885	197	2	good	good	ADJ
admet-1885	197	3	method	method	NOUN
admet-1885	197	4	would	would	AUX
admet-1885	197	5	recover	recover	VERB
admet-1885	197	6	the	the	DET
admet-1885	197	7	amount	amount	NOUN
admet-1885	197	8	of	of	ADP
admet-1885	197	9	api	api	NOUN
admet-1885	197	10	in	in	ADP
admet-1885	197	11	higher	high	ADJ
admet-1885	197	12	or	or	CCONJ
admet-1885	197	13	lower	low	ADJ
admet-1885	197	14	concentrations	concentration	NOUN
admet-1885	197	15	using	use	VERB
admet-1885	197	16	the	the	DET
admet-1885	197	17	same	same	ADJ
admet-1885	197	18	conditions	condition	NOUN
admet-1885	197	19	with	with	ADP
admet-1885	197	20	high	high	ADJ
admet-1885	197	21	accuracy	accuracy	NOUN
admet-1885	197	22	.	.	PUNCT
admet-1885	198	1	table	table	NOUN
admet-1885	198	2	4	4	NUM
admet-1885	198	3	shows	show	VERB
admet-1885	198	4	the	the	DET
admet-1885	198	5	results	result	NOUN
admet-1885	198	6	of	of	ADP
admet-1885	198	7	the	the	DET
admet-1885	198	8	recovery	recovery	NOUN
admet-1885	198	9	test	test	NOUN
admet-1885	198	10	of	of	ADP
admet-1885	198	11	ap	ap	PROPN
admet-1885	198	12	,	,	PUNCT
admet-1885	198	13	showing	show	VERB
admet-1885	198	14	the	the	DET
admet-1885	198	15	accuracy	accuracy	NOUN
admet-1885	198	16	of	of	ADP
admet-1885	198	17	measurement	measurement	NOUN
admet-1885	198	18	and	and	CCONJ
admet-1885	198	19	rsd	rsd	NOUN
admet-1885	198	20	as	as	ADP
admet-1885	198	21	a	a	DET
admet-1885	198	22	measurement	measurement	NOUN
admet-1885	198	23	of	of	ADP
admet-1885	198	24	precision	precision	NOUN
admet-1885	198	25	.	.	PUNCT
admet-1885	199	1	results	result	NOUN
admet-1885	199	2	gave	give	VERB
admet-1885	199	3	percent	percent	NOUN
admet-1885	199	4	recovery	recovery	NOUN
admet-1885	199	5	of	of	ADP
admet-1885	199	6	ap	ap	PROPN
admet-1885	199	7	from	from	ADP
admet-1885	199	8	all	all	DET
admet-1885	199	9	formulas	formula	NOUN
admet-1885	199	10	97.3	97.3	NUM
admet-1885	199	11	98.2	98.2	NUM
admet-1885	199	12	%	%	NOUN
admet-1885	199	13	with	with	ADP
admet-1885	199	14	precision	precision	NOUN
admet-1885	199	15	between	between	ADP
admet-1885	199	16	0.9	0.9	NUM
admet-1885	199	17	and	and	CCONJ
admet-1885	199	18	1	1	NUM
admet-1885	199	19	,	,	PUNCT
admet-1885	199	20	which	which	PRON
admet-1885	199	21	fulfills	fulfill	VERB
admet-1885	199	22	the	the	DET
admet-1885	199	23	criteria	criterion	NOUN
admet-1885	199	24	of	of	ADP
admet-1885	199	25	ich	ich	PROPN
admet-1885	199	26	guidelines	guideline	NOUN
admet-1885	199	27	.	.	PUNCT
admet-1885	200	1	table	table	NOUN
admet-1885	200	2	4	4	NUM
admet-1885	200	3	.	.	PUNCT
admet-1885	200	4	results	result	VERB
admet-1885	200	5	recovery	recovery	NOUN
admet-1885	200	6	test	test	NOUN
admet-1885	200	7	of	of	ADP
admet-1885	200	8	ap	ap	PROPN
admet-1885	200	9	from	from	ADP
admet-1885	200	10	capsule	capsule	ADJ
admet-1885	200	11	dosage	dosage	NOUN
admet-1885	200	12	form	form	NOUN
admet-1885	200	13	showing	show	VERB
admet-1885	200	14	accuracy	accuracy	NOUN
admet-1885	200	15	and	and	CCONJ
admet-1885	200	16	precision	precision	NOUN
admet-1885	200	17	ap	ap	PROPN
admet-1885	200	18	in	in	ADP
admet-1885	200	19	test	test	NOUN
admet-1885	200	20	formulas	formula	NOUN
admet-1885	200	21	.	.	PUNCT
admet-1885	201	1	sample	sample	NOUN
admet-1885	202	1	i	i	NOUN
admet-1885	202	2	d	d	PROPN
admet-1885	202	3	ctheoretical	ctheoretical	ADJ
admet-1885	202	4	/	/	PUNCT
admet-1885	202	5	µg	µg	ADP
admet-1885	202	6	ml-1	ml-1	PRON
admet-1885	202	7	measured	measure	VERB
admet-1885	202	8	absorbance	absorbance	NOUN
admet-1885	202	9	cmeasured	cmeasure	VERB
admet-1885	202	10	/	/	PUNCT
admet-1885	202	11	µg	µg	VERB
admet-1885	202	12	ml-1	ml-1	X
admet-1885	203	1	(	(	PUNCT
admet-1885	203	2	from	from	ADP
admet-1885	203	3	formula	formula	NOUN
admet-1885	203	4	)	)	PUNCT
admet-1885	203	5	accuracy	accuracy	NOUN
admet-1885	203	6	,	,	PUNCT
admet-1885	203	7	%	%	NOUN
admet-1885	203	8	average	average	ADJ
admet-1885	203	9	accuracy	accuracy	NOUN
admet-1885	203	10	,	,	PUNCT
admet-1885	203	11	%	%	NOUN
admet-1885	203	12	rsd	rsd	NOUN
admet-1885	203	13	,	,	PUNCT
admet-1885	203	14	%	%	NOUN
admet-1885	203	15	(	(	PUNCT
admet-1885	203	16	precision	precision	NOUN
admet-1885	203	17	)	)	PUNCT
admet-1885	203	18	sample1	sample1	NOUN
admet-1885	203	19	-	-	PUNCT
admet-1885	203	20	1	1	NUM
admet-1885	203	21	40.0	40.0	NUM
admet-1885	203	22	0.359900	0.359900	NUM
admet-1885	203	23	39.00	39.00	NUM
admet-1885	203	24	97.5	97.5	NUM
admet-1885	203	25	97.9	97.9	NUM
admet-1885	203	26	0.9	0.9	NUM
admet-1885	203	27	sample1	sample1	NOUN
admet-1885	203	28	-	-	PUNCT
admet-1885	203	29	2	2	NUM
admet-1885	203	30	40.0	40.0	NUM
admet-1885	203	31	0.362060	0.362060	NUM
admet-1885	203	32	39.20	39.20	NUM
admet-1885	203	33	98.0	98.0	NUM
admet-1885	203	34	sample1	sample1	NOUN
admet-1885	203	35	-	-	PUNCT
admet-1885	203	36	3	3	NUM
admet-1885	203	37	40.0	40.0	NUM
admet-1885	203	38	0.362924	0.362924	NUM
admet-1885	203	39	39.28	39.28	NUM
admet-1885	203	40	98.2	98.2	NUM
admet-1885	203	41	sample2	sample2	NOUN
admet-1885	203	42	-	-	PUNCT
admet-1885	203	43	1	1	NUM
admet-1885	203	44	60.0	60.0	NUM
admet-1885	203	45	0.570500	0.570500	NUM
admet-1885	203	46	58.50	58.50	NUM
admet-1885	203	47	97.5	97.5	NUM
admet-1885	203	48	98.2	98.2	NUM
admet-1885	203	49	1.0	1.0	NUM
admet-1885	203	50	sample2	sample2	NOUN
admet-1885	203	51	-	-	PUNCT
admet-1885	203	52	2	2	NUM
admet-1885	203	53	60.0	60.0	NUM
admet-1885	203	54	0.574388	0.574388	NUM
admet-1885	203	55	58.86	58.86	NUM
admet-1885	203	56	98.1	98.1	NUM
admet-1885	203	57	sample2	sample2	NOUN
admet-1885	203	58	-	-	PUNCT
admet-1885	203	59	3	3	NUM
admet-1885	203	60	60.0	60.0	NUM
admet-1885	203	61	0.580220	0.580220	NUM
admet-1885	203	62	59.40	59.40	NUM
admet-1885	203	63	99.0	99.0	NUM
admet-1885	203	64	sample3	sample3	NOUN
admet-1885	203	65	-	-	SYM
admet-1885	203	66	1	1	NUM
admet-1885	203	67	90.0	90.0	NUM
admet-1885	203	68	0.900980	0.900980	NUM
admet-1885	203	69	89.10	89.10	NUM
admet-1885	203	70	99.0	99.0	NUM
admet-1885	203	71	97.3	97.3	NUM
admet-1885	203	72	0.97	0.97	NUM
admet-1885	203	73	sample3	sample3	NOUN
admet-1885	203	74	-	-	SYM
admet-1885	203	75	2	2	NUM
admet-1885	203	76	90.0	90.0	NUM
admet-1885	203	77	0.881540	0.881540	NUM
admet-1885	203	78	87.30	87.30	NUM
admet-1885	203	79	97.0	97.0	NUM
admet-1885	203	80	sample3	sample3	NOUN
admet-1885	203	81	-	-	PUNCT
admet-1885	203	82	3	3	NUM
admet-1885	203	83	90.0	90.0	NUM
admet-1885	203	84	0.879596	0.879596	NUM
admet-1885	203	85	87.12	87.12	NUM
admet-1885	203	86	9.86	9.86	NUM
admet-1885	203	87	robustness	robustness	NOUN
admet-1885	203	88	studies	study	NOUN
admet-1885	203	89	the	the	DET
admet-1885	203	90	effect	effect	NOUN
admet-1885	203	91	of	of	ADP
admet-1885	203	92	variation	variation	NOUN
admet-1885	203	93	in	in	ADP
admet-1885	203	94	conditions	condition	NOUN
admet-1885	203	95	on	on	ADP
admet-1885	203	96	the	the	DET
admet-1885	203	97	result	result	NOUN
admet-1885	203	98	and	and	CCONJ
admet-1885	203	99	tests	test	VERB
admet-1885	203	100	how	how	SCONJ
admet-1885	203	101	much	much	ADJ
admet-1885	203	102	the	the	DET
admet-1885	203	103	method	method	NOUN
admet-1885	203	104	is	be	AUX
admet-1885	203	105	resistant	resistant	ADJ
admet-1885	203	106	to	to	ADP
admet-1885	203	107	these	these	DET
admet-1885	203	108	changes	change	NOUN
admet-1885	203	109	.	.	PUNCT
admet-1885	204	1	different	different	ADJ
admet-1885	204	2	conditions	condition	NOUN
admet-1885	204	3	were	be	AUX
admet-1885	204	4	chosen	choose	VERB
admet-1885	204	5	for	for	ADP
admet-1885	204	6	measuring	measure	VERB
admet-1885	204	7	a	a	DET
admet-1885	204	8	sample	sample	NOUN
admet-1885	204	9	of	of	ADP
admet-1885	204	10	50	50	NUM
admet-1885	204	11	µg	µg	NOUN
admet-1885	204	12	/	/	SYM
admet-1885	204	13	ml	ml	NOUN
admet-1885	204	14	ap	ap	PROPN
admet-1885	204	15	.	.	PUNCT
admet-1885	205	1	the	the	DET
admet-1885	205	2	accuracy	accuracy	NOUN
admet-1885	205	3	of	of	ADP
admet-1885	205	4	measurement	measurement	NOUN
admet-1885	205	5	of	of	ADP
admet-1885	205	6	ap	ap	PROPN
admet-1885	205	7	ranged	range	VERB
admet-1885	205	8	between	between	ADP
admet-1885	205	9	97.3	97.3	NUM
admet-1885	205	10	to	to	PART
admet-1885	205	11	99.8	99.8	NUM
admet-1885	205	12	%	%	NOUN
admet-1885	205	13	,	,	PUNCT
admet-1885	205	14	which	which	PRON
admet-1885	205	15	indicated	indicate	VERB
admet-1885	205	16	high	high	ADJ
admet-1885	205	17	resistance	resistance	NOUN
admet-1885	205	18	of	of	ADP
admet-1885	205	19	the	the	DET
admet-1885	205	20	method	method	NOUN
admet-1885	205	21	to	to	PART
admet-1885	205	22	changes	change	NOUN
admet-1885	205	23	in	in	ADP
admet-1885	205	24	the	the	DET
admet-1885	205	25	condition	condition	NOUN
admet-1885	205	26	specified	specify	VERB
admet-1885	205	27	,	,	PUNCT
admet-1885	205	28	as	as	SCONJ
admet-1885	205	29	shown	show	VERB
admet-1885	205	30	in	in	ADP
admet-1885	205	31	table	table	NOUN
admet-1885	205	32	5	5	NUM
admet-1885	205	33	.	.	PUNCT
admet-1885	206	1	the	the	DET
admet-1885	206	2	wavelength	wavelength	NOUN
admet-1885	206	3	was	be	AUX
admet-1885	206	4	changed	change	VERB
admet-1885	206	5	from	from	ADP
admet-1885	206	6	278	278	NUM
admet-1885	206	7	-	-	SYM
admet-1885	206	8	275	275	NUM
admet-1885	206	9	nm	nm	PRON
admet-1885	206	10	one	one	NUM
admet-1885	206	11	time	time	NOUN
admet-1885	206	12	to	to	ADP
admet-1885	206	13	285	285	NUM
admet-1885	206	14	another	another	DET
admet-1885	206	15	time	time	NOUN
admet-1885	206	16	to	to	PART
admet-1885	206	17	test	test	VERB
admet-1885	206	18	the	the	DET
admet-1885	206	19	possibility	possibility	NOUN
admet-1885	206	20	of	of	ADP
admet-1885	206	21	a	a	DET
admet-1885	206	22	result	result	NOUN
admet-1885	206	23	change	change	NOUN
admet-1885	206	24	.	.	PUNCT
admet-1885	207	1	two	two	NUM
admet-1885	207	2	instruments	instrument	NOUN
admet-1885	207	3	were	be	AUX
admet-1885	207	4	used	use	VERB
admet-1885	207	5	,	,	PUNCT
admet-1885	207	6	and	and	CCONJ
admet-1885	207	7	the	the	DET
admet-1885	207	8	temperature	temperature	NOUN
admet-1885	207	9	of	of	ADP
admet-1885	207	10	the	the	DET
admet-1885	207	11	test	test	NOUN
admet-1885	207	12	solution	solution	NOUN
admet-1885	207	13	was	be	AUX
admet-1885	207	14	elevated	elevate	VERB
admet-1885	207	15	to	to	ADP
admet-1885	207	16	30	30	NUM
admet-1885	207	17	°	°	NOUN
admet-1885	207	18	c	c	NOUN
admet-1885	207	19	as	as	ADV
admet-1885	207	20	well	well	ADV
admet-1885	207	21	as	as	ADV
admet-1885	207	22	blank	blank	ADJ
admet-1885	207	23	.	.	PUNCT
admet-1885	208	1	these	these	DET
admet-1885	208	2	parameters	parameter	NOUN
admet-1885	208	3	showed	show	VERB
admet-1885	208	4	a	a	DET
admet-1885	208	5	very	very	ADV
admet-1885	208	6	slight	slight	ADJ
admet-1885	208	7	difference	difference	NOUN
admet-1885	208	8	in	in	ADP
admet-1885	208	9	the	the	DET
admet-1885	208	10	accuracy	accuracy	NOUN
admet-1885	208	11	of	of	ADP
admet-1885	208	12	the	the	DET
admet-1885	208	13	measured	measure	VERB
admet-1885	208	14	concentration	concentration	NOUN
admet-1885	208	15	tested	test	VERB
admet-1885	208	16	.	.	PUNCT
admet-1885	209	1	in	in	ADP
admet-1885	209	2	conclusion	conclusion	NOUN
admet-1885	209	3	,	,	PUNCT
admet-1885	209	4	the	the	DET
admet-1885	209	5	method	method	NOUN
admet-1885	209	6	successfully	successfully	ADV
admet-1885	209	7	handled	handle	VERB
admet-1885	209	8	some	some	DET
admet-1885	209	9	changes	change	NOUN
admet-1885	209	10	in	in	ADP
admet-1885	209	11	conditions	condition	NOUN
admet-1885	209	12	within	within	ADP
admet-1885	209	13	the	the	DET
admet-1885	209	14	ich	ich	NOUN
admet-1885	209	15	guidelines	guideline	NOUN
admet-1885	209	16	'	'	PART
admet-1885	209	17	requirements	requirement	NOUN
admet-1885	209	18	.	.	PUNCT
admet-1885	210	1	table	table	NOUN
admet-1885	210	2	5	5	NUM
admet-1885	210	3	.	.	PUNCT
admet-1885	211	1	results	result	NOUN
admet-1885	211	2	of	of	ADP
admet-1885	211	3	robustness	robustness	NOUN
admet-1885	211	4	of	of	ADP
admet-1885	211	5	method	method	NOUN
admet-1885	211	6	ap	ap	PROPN
admet-1885	211	7	(	(	PUNCT
admet-1885	211	8	50	50	NUM
admet-1885	211	9	µg	µg	ADV
admet-1885	211	10	ml-1	ml-1	X
admet-1885	211	11	)	)	PUNCT
admet-1885	211	12	test	test	NOUN
admet-1885	211	13	showing	show	VERB
admet-1885	211	14	different	different	ADJ
admet-1885	211	15	conditions	condition	NOUN
admet-1885	211	16	used	use	VERB
admet-1885	211	17	,	,	PUNCT
admet-1885	211	18	accuracy	accuracy	NOUN
admet-1885	211	19	and	and	CCONJ
admet-1885	211	20	precision	precision	NOUN
admet-1885	211	21	.	.	PUNCT
admet-1885	212	1	sample	sample	NOUN
admet-1885	212	2	i	i	PROPN
admet-1885	212	3	d	d	PROPN
admet-1885	212	4	absorban	absorban	PROPN
admet-1885	212	5	ce	ce	PROPN
admet-1885	212	6	c/	c/	NOUN
admet-1885	212	7	µg	µg	ADP
admet-1885	212	8	ml-1	ml-1	PRON
admet-1885	212	9	accuracy	accuracy	NOUN
admet-1885	212	10	,	,	PUNCT
admet-1885	212	11	%	%	NOUN
admet-1885	212	12	rsd	rsd	NOUN
admet-1885	212	13	,	,	PUNCT
admet-1885	212	14	%	%	NOUN
admet-1885	212	15	theoretical	theoretical	ADJ
admet-1885	212	16	measured	measure	VERB
admet-1885	212	17	(	(	PUNCT
admet-1885	212	18	n=3	n=3	NOUN
admet-1885	212	19	)	)	PUNCT
admet-1885	212	20	robustness	robustness	NOUN
admet-1885	212	21	+	+	CCONJ
admet-1885	212	22	5	5	NUM
admet-1885	212	23	nm	nm	NOUN
admet-1885	212	24	(	(	PUNCT
admet-1885	212	25	285	285	NUM
admet-1885	212	26	nm	nm	NOUN
admet-1885	212	27	)	)	PUNCT
admet-1885	212	28	0.693	0.693	NUM
admet-1885	212	29	50	50	NUM
admet-1885	212	30	49.86	49.86	NUM
admet-1885	212	31	99.8	99.8	NUM
admet-1885	212	32	0.6	0.6	NUM
admet-1885	212	33	robustness	robustness	NOUN
admet-1885	212	34	–	–	PUNCT
admet-1885	212	35	5	5	NUM
admet-1885	212	36	nm	nm	NOUN
admet-1885	212	37	(	(	PUNCT
admet-1885	212	38	275	275	NUM
admet-1885	212	39	nm	nm	NOUN
admet-1885	212	40	)	)	PUNCT
admet-1885	212	41	0.691	0.691	NUM
admet-1885	212	42	50	50	NUM
admet-1885	212	43	49.72	49.72	NUM
admet-1885	212	44	99.6	99.6	NUM
admet-1885	212	45	0.9	0.9	NUM
admet-1885	212	46	robustness	robustness	NOUN
admet-1885	212	47	-	-	PUNCT
admet-1885	212	48	instrument	instrument	NOUN
admet-1885	212	49	1	1	NUM
admet-1885	212	50	0.687	0.687	NUM
admet-1885	212	51	50	50	NUM
admet-1885	212	52	49.37	49.37	NUM
admet-1885	212	53	99.1	99.1	NUM
admet-1885	212	54	0.58	0.58	NUM
admet-1885	212	55	robustness	robustness	NOUN
admet-1885	212	56	-	-	PUNCT
admet-1885	212	57	instrument	instrument	NOUN
admet-1885	212	58	2	2	NUM
admet-1885	212	59	0.674	0.674	NUM
admet-1885	212	60	50	50	NUM
admet-1885	212	61	48.11	48.11	NUM
admet-1885	212	62	97.3	97.3	NUM
admet-1885	212	63	1.2	1.2	NUM
admet-1885	212	64	robustness	robustness	NOUN
admet-1885	212	65	30oc	30oc	NOUN
admet-1885	212	66	0.690	0.690	NUM
admet-1885	212	67	50	50	NUM
admet-1885	212	68	48.78	48.78	NUM
admet-1885	212	69	98.4	98.4	NUM
admet-1885	212	70	0.7	0.7	NUM
admet-1885	212	71	ap	ap	NOUN
admet-1885	212	72	in	in	ADP
admet-1885	212	73	methanol	methanol	NOUN
admet-1885	212	74	50	50	NUM
admet-1885	212	75	49.1	49.1	NUM
admet-1885	212	76	98.2	98.2	NUM
admet-1885	212	77	0.9	0.9	NUM
admet-1885	212	78	characterization	characterization	NOUN
admet-1885	212	79	of	of	ADP
admet-1885	212	80	the	the	DET
admet-1885	212	81	prepared	prepared	ADJ
admet-1885	212	82	complex	complex	NOUN
admet-1885	212	83	the	the	DET
admet-1885	212	84	prepared	prepare	VERB
admet-1885	212	85	complexes	complex	NOUN
admet-1885	212	86	by	by	ADP
admet-1885	212	87	the	the	DET
admet-1885	212	88	three	three	NUM
admet-1885	212	89	mentioned	mention	VERB
admet-1885	212	90	methods	method	NOUN
admet-1885	212	91	were	be	AUX
admet-1885	212	92	evaluated	evaluate	VERB
admet-1885	212	93	to	to	PART
admet-1885	212	94	confirm	confirm	VERB
admet-1885	212	95	complex	complex	ADJ
admet-1885	212	96	formation	formation	NOUN
admet-1885	212	97	,	,	PUNCT
admet-1885	212	98	percent	percent	NOUN
admet-1885	212	99	yield	yield	NOUN
admet-1885	212	100	and	and	CCONJ
admet-1885	212	101	ap	ap	PROPN
admet-1885	212	102	content	content	NOUN
admet-1885	212	103	in	in	ADP
admet-1885	212	104	each	each	DET
admet-1885	212	105	powder	powder	NOUN
admet-1885	212	106	complex	complex	NOUN
admet-1885	212	107	prepared	prepare	VERB
admet-1885	212	108	.	.	PUNCT
admet-1885	213	1	based	base	VERB
admet-1885	213	2	on	on	ADP
admet-1885	213	3	the	the	DET
admet-1885	213	4	results	result	NOUN
admet-1885	213	5	,	,	PUNCT
admet-1885	213	6	the	the	DET
admet-1885	213	7	method	method	NOUN
admet-1885	213	8	of	of	ADP
admet-1885	213	9	preparation	preparation	NOUN
admet-1885	213	10	was	be	AUX
admet-1885	213	11	evaluated	evaluate	VERB
admet-1885	213	12	,	,	PUNCT
admet-1885	213	13	and	and	CCONJ
admet-1885	213	14	the	the	DET
admet-1885	213	15	best	good	ADJ
admet-1885	213	16	complex	complex	NOUN
admet-1885	213	17	was	be	AUX
admet-1885	213	18	chosen	choose	VERB
admet-1885	213	19	for	for	ADP
admet-1885	213	20	further	further	ADJ
admet-1885	213	21	work	work	NOUN
admet-1885	213	22	.	.	PUNCT
admet-1885	214	1	ftir	ftir	PROPN
admet-1885	214	2	analysis	analysis	NOUN
admet-1885	214	3	was	be	AUX
admet-1885	214	4	done	do	VERB
admet-1885	214	5	on	on	ADP
admet-1885	214	6	all	all	DET
admet-1885	214	7	the	the	DET
admet-1885	214	8	prepared	prepared	ADJ
admet-1885	214	9	complexes	complex	NOUN
admet-1885	214	10	.	.	PUNCT
admet-1885	215	1	below	below	ADV
admet-1885	215	2	are	be	AUX
admet-1885	215	3	a	a	DET
admet-1885	215	4	few	few	ADJ
admet-1885	215	5	examples	example	NOUN
admet-1885	215	6	of	of	ADP
admet-1885	215	7	the	the	DET
admet-1885	215	8	prepared	prepared	ADJ
admet-1885	215	9	complexes	complex	NOUN
admet-1885	215	10	.	.	PUNCT
admet-1885	216	1	figure	figure	NOUN
admet-1885	216	2	4	4	NUM
admet-1885	216	3	shows	show	VERB
admet-1885	216	4	the	the	DET
admet-1885	216	5	ftir	ftir	PROPN
admet-1885	216	6	spectrum	spectrum	PROPN
admet-1885	216	7	of	of	ADP
admet-1885	216	8	ap	ap	PROPN
admet-1885	216	9	.	.	PUNCT
admet-1885	217	1	figure	figure	NOUN
admet-1885	217	2	5	5	NUM
admet-1885	217	3	shows	show	VERB
admet-1885	217	4	the	the	DET
admet-1885	217	5	ftir	ftir	PROPN
admet-1885	217	6	overlay	overlay	NOUN
admet-1885	217	7	spectra	spectra	NOUN
admet-1885	217	8	of	of	ADP
admet-1885	217	9	ap	ap	PROPN
admet-1885	217	10	(	(	PUNCT
admet-1885	217	11	a	a	NOUN
admet-1885	217	12	)	)	PUNCT
admet-1885	217	13	,	,	PUNCT
admet-1885	217	14	apβcd	apβcd	VERB
admet-1885	217	15	(	(	PUNCT
admet-1885	217	16	b	b	NOUN
admet-1885	217	17	)	)	PUNCT
admet-1885	217	18	,	,	PUNCT
admet-1885	217	19	and	and	CCONJ
admet-1885	217	20	ap	ap	VERB
admet-1885	217	21	-	-	PUNCT
admet-1885	217	22	hpβcd	hpβcd	ADJ
admet-1885	217	23	(	(	PUNCT
admet-1885	217	24	c	c	NOUN
admet-1885	217	25	)	)	PUNCT
admet-1885	217	26	results	result	NOUN
admet-1885	217	27	.	.	PUNCT
admet-1885	218	1	https://doi.org/10.5599/admet.1885	https://doi.org/10.5599/admet.1885	PROPN
admet-1885	218	2	z.	z.	PROPN
admet-1885	218	3	n.	n.	PROPN
admet-1885	218	4	salman	salman	PROPN
admet-1885	218	5	et	et	PROPN
admet-1885	218	6	al	al	PROPN
admet-1885	218	7	.	.	PROPN
admet-1885	218	8	admet	admet	PROPN
admet-1885	218	9	&	&	CCONJ
admet-1885	218	10	dmpk	dmpk	PROPN
admet-1885	218	11	11(4	11(4	NUM
admet-1885	218	12	)	)	PUNCT
admet-1885	218	13	(	(	PUNCT
admet-1885	218	14	2023	2023	NUM
admet-1885	218	15	)	)	PUNCT
admet-1885	218	16	533	533	NUM
admet-1885	218	17	-	-	SYM
admet-1885	218	18	550	550	NUM
admet-1885	218	19	542	542	NUM
admet-1885	218	20	ap	ap	NOUN
admet-1885	218	21	identifying	identify	VERB
admet-1885	218	22	peaks	peak	NOUN
admet-1885	218	23	observed	observe	VERB
admet-1885	218	24	were	be	AUX
admet-1885	218	25	:	:	PUNCT
admet-1885	218	26	(	(	PUNCT
admet-1885	218	27	1	1	X
admet-1885	218	28	)	)	PUNCT
admet-1885	218	29	3325.0	3325.0	NUM
admet-1885	218	30	cm	cm	NOUN
admet-1885	218	31	-1	-1	NOUN
admet-1885	218	32	(	(	PUNCT
admet-1885	218	33	n	n	CCONJ
admet-1885	218	34	-	-	PUNCT
admet-1885	218	35	h	h	NOUN
admet-1885	218	36	stretching	stretching	NOUN
admet-1885	218	37	of	of	ADP
admet-1885	218	38	sulphonamido	sulphonamido	PROPN
admet-1885	218	39	group	group	NOUN
admet-1885	218	40	)	)	PUNCT
admet-1885	218	41	,	,	PUNCT
admet-1885	218	42	(	(	PUNCT
admet-1885	218	43	2	2	X
admet-1885	218	44	)	)	PUNCT
admet-1885	218	45	3300	3300	NUM
admet-1885	218	46	to	to	ADP
admet-1885	218	47	3500	3500	NUM
admet-1885	218	48	cm-1	cm-1	X
admet-1885	218	49	(	(	PUNCT
admet-1885	218	50	n	n	CCONJ
admet-1885	218	51	-	-	PUNCT
admet-1885	218	52	h	h	NOUN
admet-1885	218	53	stretching	stretching	NOUN
admet-1885	218	54	of	of	ADP
admet-1885	218	55	amido	amido	NOUN
admet-1885	218	56	group	group	NOUN
admet-1885	218	57	)	)	PUNCT
admet-1885	218	58	(	(	PUNCT
admet-1885	218	59	3	3	X
admet-1885	218	60	)	)	PUNCT
admet-1885	218	61	2930	2930	NUM
admet-1885	218	62	cm-1	cm-1	X
admet-1885	218	63	(	(	PUNCT
admet-1885	218	64	ch	ch	NOUN
admet-1885	218	65	stretching	stretching	NOUN
admet-1885	218	66	of	of	ADP
admet-1885	218	67	ch2	ch2	PROPN
admet-1885	218	68	)	)	PUNCT
admet-1885	218	69	and	and	CCONJ
admet-1885	218	70	(	(	PUNCT
admet-1885	218	71	4	4	X
admet-1885	218	72	)	)	PUNCT
admet-1885	218	73	characteristic	characteristic	ADJ
admet-1885	218	74	c	c	X
admet-1885	218	75	=	=	NOUN
admet-1885	218	76	o	o	X
admet-1885	218	77	of	of	ADP
admet-1885	218	78	amide	amide	NOUN
admet-1885	218	79	at	at	ADP
admet-1885	218	80	1628.9	1628.9	NUM
admet-1885	218	81	cm-1	cm-1	NOUN
admet-1885	218	82	.	.	PUNCT
admet-1885	219	1	the	the	DET
admet-1885	219	2	prominent	prominent	ADJ
admet-1885	219	3	peaks	peak	NOUN
admet-1885	219	4	for	for	ADP
admet-1885	219	5	βcd	βcd	NUM
admet-1885	219	6	alone	alone	ADV
admet-1885	219	7	are	be	AUX
admet-1885	219	8	3398	3398	NUM
admet-1885	219	9	cm-1	cm-1	X
admet-1885	220	1	(	(	PUNCT
admet-1885	220	2	o	o	NOUN
admet-1885	220	3	-	-	NOUN
admet-1885	220	4	h	h	NOUN
admet-1885	220	5	)	)	PUNCT
admet-1885	220	6	,	,	PUNCT
admet-1885	220	7	2930	2930	NUM
admet-1885	220	8	cm-1	cm-1	X
admet-1885	220	9	(	(	PUNCT
admet-1885	220	10	c	c	X
admet-1885	220	11	-	-	PUNCT
admet-1885	220	12	h	h	NOUN
admet-1885	220	13	stretching	stretching	NOUN
admet-1885	220	14	)	)	PUNCT
admet-1885	220	15	,	,	PUNCT
admet-1885	220	16	1628	1628	NUM
admet-1885	220	17	to	to	ADP
admet-1885	220	18	1598	1598	NUM
admet-1885	220	19	cm-1	cm-1	PART
admet-1885	220	20	(	(	PUNCT
admet-1885	220	21	h	h	NOUN
admet-1885	220	22	-	-	PUNCT
admet-1885	220	23	o	o	NOUN
admet-1885	220	24	-	-	ADJ
admet-1885	220	25	h	h	ADJ
admet-1885	220	26	bending	bending	NOUN
admet-1885	220	27	)	)	PUNCT
admet-1885	220	28	,	,	PUNCT
admet-1885	220	29	1156	1156	NUM
admet-1885	220	30	cm-1	cm-1	X
admet-1885	220	31	(	(	PUNCT
admet-1885	220	32	c	c	X
admet-1885	220	33	-	-	PUNCT
admet-1885	220	34	o	o	NOUN
admet-1885	220	35	stretching	stretching	NOUN
admet-1885	220	36	)	)	PUNCT
admet-1885	220	37	,	,	PUNCT
admet-1885	220	38	1028	1028	NUM
admet-1885	220	39	cm-1	cm-1	X
admet-1885	220	40	(	(	PUNCT
admet-1885	220	41	c	c	NOUN
admet-1885	220	42	-	-	PUNCT
admet-1885	220	43	o	o	NOUN
admet-1885	220	44	-	-	NOUN
admet-1885	220	45	c	c	NOUN
admet-1885	220	46	stretching	stretching	NOUN
admet-1885	220	47	)	)	PUNCT
admet-1885	220	48	.	.	PUNCT
admet-1885	221	1	the	the	DET
admet-1885	221	2	ir	ir	ADJ
admet-1885	221	3	-	-	ADJ
admet-1885	221	4	abundant	abundant	ADJ
admet-1885	221	5	peaks	peak	NOUN
admet-1885	221	6	for	for	ADP
admet-1885	221	7	hpβcd	hpβcd	ADJ
admet-1885	221	8	alone	alone	ADV
admet-1885	221	9	are	be	AUX
admet-1885	221	10	3395	3395	NUM
admet-1885	221	11	cm-1	cm-1	X
admet-1885	221	12	(	(	PUNCT
admet-1885	221	13	o	o	NOUN
admet-1885	221	14	-	-	NOUN
admet-1885	221	15	h	h	NOUN
admet-1885	221	16	)	)	PUNCT
admet-1885	221	17	,	,	PUNCT
admet-1885	221	18	2930	2930	NUM
admet-1885	221	19	cm-1	cm-1	X
admet-1885	222	1	(	(	PUNCT
admet-1885	222	2	c	c	X
admet-1885	222	3	-	-	PUNCT
admet-1885	222	4	h	h	NOUN
admet-1885	222	5	stretching	stretching	NOUN
admet-1885	222	6	)	)	PUNCT
admet-1885	222	7	,	,	PUNCT
admet-1885	222	8	1628	1628	NUM
admet-1885	222	9	cm-1	cm-1	X
admet-1885	222	10	(	(	PUNCT
admet-1885	222	11	h	h	NOUN
admet-1885	222	12	-	-	PUNCT
admet-1885	223	1	o	o	NOUN
admet-1885	223	2	-	-	ADJ
admet-1885	223	3	h	h	ADJ
admet-1885	223	4	bending	bending	NOUN
admet-1885	223	5	)	)	PUNCT
admet-1885	223	6	,	,	PUNCT
admet-1885	223	7	1156	1156	NUM
admet-1885	223	8	cm-1	cm-1	X
admet-1885	223	9	(	(	PUNCT
admet-1885	223	10	c	c	X
admet-1885	223	11	-	-	PUNCT
admet-1885	223	12	o	o	NOUN
admet-1885	223	13	stretching	stretching	NOUN
admet-1885	223	14	)	)	PUNCT
admet-1885	223	15	,	,	PUNCT
admet-1885	223	16	1032	1032	NUM
admet-1885	223	17	cm-1	cm-1	X
admet-1885	223	18	(	(	PUNCT
admet-1885	223	19	c	c	NOUN
admet-1885	223	20	-	-	PUNCT
admet-1885	223	21	o	o	NOUN
admet-1885	223	22	-	-	NOUN
admet-1885	223	23	c	c	NOUN
admet-1885	223	24	stretching	stretching	NOUN
admet-1885	223	25	)	)	PUNCT
admet-1885	223	26	.	.	PUNCT
admet-1885	224	1	wavenumber	wavenumber	NOUN
admet-1885	224	2	,	,	PUNCT
admet-1885	224	3	cm-1	cm-1	NOUN
admet-1885	224	4	figure	figure	NOUN
admet-1885	224	5	4	4	NUM
admet-1885	224	6	.	.	PUNCT
admet-1885	224	7	ftir	ftir	PROPN
admet-1885	224	8	spectrum	spectrum	PROPN
admet-1885	224	9	of	of	ADP
admet-1885	224	10	ap	ap	PROPN
admet-1885	224	11	showing	show	VERB
admet-1885	224	12	the	the	DET
admet-1885	224	13	major	major	ADJ
admet-1885	224	14	peaks	peak	NOUN
admet-1885	224	15	(	(	PUNCT
admet-1885	224	16	1	1	NUM
admet-1885	224	17	)	)	PUNCT
admet-1885	224	18	3325.0	3325.0	NUM
admet-1885	224	19	cm-1	cm-1	X
admet-1885	224	20	(	(	PUNCT
admet-1885	224	21	n	n	CCONJ
admet-1885	224	22	-	-	PUNCT
admet-1885	224	23	h	h	NOUN
admet-1885	224	24	stretching	stretching	NOUN
admet-1885	224	25	of	of	ADP
admet-1885	224	26	sulphonamido	sulphonamido	ADJ
admet-1885	224	27	gr	gr	PROPN
admet-1885	224	28	.	.	PUNCT
admet-1885	224	29	)	)	PUNCT
admet-1885	224	30	,	,	PUNCT
admet-1885	224	31	(	(	PUNCT
admet-1885	224	32	2	2	X
admet-1885	224	33	)	)	PUNCT
admet-1885	224	34	3300	3300	NUM
admet-1885	224	35	-	-	SYM
admet-1885	224	36	3500	3500	NUM
admet-1885	224	37	cm-1	cm-1	X
admet-1885	224	38	(	(	PUNCT
admet-1885	224	39	n	n	CCONJ
admet-1885	224	40	-	-	PUNCT
admet-1885	224	41	h	h	NOUN
admet-1885	224	42	stretching	stretching	NOUN
admet-1885	224	43	of	of	ADP
admet-1885	224	44	amido	amido	NOUN
admet-1885	224	45	gr	gr	PROPN
admet-1885	224	46	.	.	PUNCT
admet-1885	224	47	)	)	PUNCT
admet-1885	225	1	(	(	PUNCT
admet-1885	225	2	3	3	X
admet-1885	225	3	)	)	PUNCT
admet-1885	225	4	2930	2930	NUM
admet-1885	225	5	cm-1	cm-1	X
admet-1885	226	1	(	(	PUNCT
admet-1885	226	2	ch	ch	NOUN
admet-1885	226	3	stretching	stretching	NOUN
admet-1885	226	4	of	of	ADP
admet-1885	226	5	ch2	ch2	PROPN
admet-1885	226	6	)	)	PUNCT
admet-1885	226	7	and	and	CCONJ
admet-1885	226	8	(	(	PUNCT
admet-1885	226	9	4	4	X
admet-1885	226	10	)	)	PUNCT
admet-1885	226	11	characteristic	characteristic	ADJ
admet-1885	226	12	c	c	X
admet-1885	226	13	=	=	NOUN
admet-1885	226	14	o	o	X
admet-1885	226	15	of	of	ADP
admet-1885	226	16	amide	amide	NOUN
admet-1885	226	17	at	at	ADP
admet-1885	226	18	1628.9	1628.9	NUM
admet-1885	226	19	cm-1	cm-1	NOUN
admet-1885	226	20	.	.	PUNCT
admet-1885	227	1	wavenumber	wavenumber	PROPN
admet-1885	227	2	,	,	PUNCT
admet-1885	227	3	cm-1	cm-1	NOUN
admet-1885	227	4	figure	figure	NOUN
admet-1885	227	5	5	5	NUM
admet-1885	227	6	.	.	PUNCT
admet-1885	228	1	overlay	overlay	NOUN
admet-1885	228	2	spectra	spectra	NOUN
admet-1885	228	3	of	of	ADP
admet-1885	228	4	ap	ap	PROPN
admet-1885	228	5	(	(	PUNCT
admet-1885	228	6	a	a	NOUN
admet-1885	228	7	)	)	PUNCT
admet-1885	228	8	,	,	PUNCT
admet-1885	228	9	ap	ap	PROPN
admet-1885	228	10	-	-	PUNCT
admet-1885	228	11	βcd	βcd	NOUN
admet-1885	228	12	(	(	PUNCT
admet-1885	228	13	b	b	NOUN
admet-1885	228	14	)	)	PUNCT
admet-1885	228	15	,	,	PUNCT
admet-1885	228	16	and	and	CCONJ
admet-1885	228	17	ap	ap	VERB
admet-1885	228	18	-	-	PUNCT
admet-1885	228	19	hpβcd	hpβcd	ADJ
admet-1885	228	20	(	(	PUNCT
admet-1885	228	21	c	c	NOUN
admet-1885	228	22	)	)	PUNCT
admet-1885	228	23	.	.	PUNCT
admet-1885	229	1	the	the	DET
admet-1885	229	2	most	most	ADV
admet-1885	229	3	characteristic	characteristic	ADJ
admet-1885	229	4	peaks	peak	NOUN
admet-1885	229	5	in	in	ADP
admet-1885	229	6	the	the	DET
admet-1885	229	7	two	two	NUM
admet-1885	229	8	complexes	complex	NOUN
admet-1885	229	9	ap	ap	PROPN
admet-1885	229	10	-	-	PUNCT
admet-1885	229	11	βcd	βcd	NOUN
admet-1885	229	12	(	(	PUNCT
admet-1885	229	13	b	b	NOUN
admet-1885	229	14	)	)	PUNCT
admet-1885	229	15	,	,	PUNCT
admet-1885	229	16	and	and	CCONJ
admet-1885	229	17	ap	ap	VERB
admet-1885	229	18	-	-	PUNCT
admet-1885	229	19	hpβcd	hpβcd	ADJ
admet-1885	229	20	(	(	PUNCT
admet-1885	229	21	c	c	NOUN
admet-1885	229	22	)	)	PUNCT
admet-1885	229	23	appeared	appear	VERB
admet-1885	229	24	with	with	ADP
admet-1885	229	25	less	less	ADJ
admet-1885	229	26	intensity	intensity	NOUN
admet-1885	229	27	of	of	ADP
admet-1885	229	28	the	the	DET
admet-1885	229	29	c	c	PROPN
admet-1885	229	30	=	=	NOUN
admet-1885	229	31	o	o	NOUN
admet-1885	229	32	amide	amide	NOUN
admet-1885	229	33	group	group	NOUN
admet-1885	229	34	of	of	ADP
admet-1885	229	35	ap	ap	PROPN
admet-1885	229	36	,	,	PUNCT
admet-1885	229	37	which	which	PRON
admet-1885	229	38	might	might	AUX
admet-1885	229	39	be	be	AUX
admet-1885	229	40	attributed	attribute	VERB
admet-1885	229	41	to	to	ADP
admet-1885	229	42	the	the	DET
admet-1885	229	43	hidden	hidden	ADJ
admet-1885	229	44	nature	nature	NOUN
admet-1885	229	45	of	of	ADP
admet-1885	229	46	this	this	DET
admet-1885	229	47	group	group	NOUN
admet-1885	229	48	inside	inside	ADP
admet-1885	229	49	the	the	DET
admet-1885	229	50	cone	cone	NOUN
admet-1885	229	51	of	of	ADP
admet-1885	229	52	the	the	DET
admet-1885	229	53	cds	cd	NOUN
admet-1885	229	54	.	.	PUNCT
admet-1885	230	1	tr	tr	VERB
admet-1885	230	2	an	an	DET
admet-1885	230	3	sm	sm	NOUN
admet-1885	230	4	it	it	PRON
admet-1885	230	5	ta	ta	ADP
admet-1885	230	6	n	n	PROPN
admet-1885	230	7	ce	ce	PROPN
admet-1885	230	8	,	,	PUNCT
admet-1885	230	9	%	%	INTJ
admet-1885	230	10	tr	tr	VERB
admet-1885	230	11	an	an	DET
admet-1885	230	12	sm	sm	NOUN
admet-1885	230	13	it	it	PRON
admet-1885	230	14	ta	ta	ADP
admet-1885	230	15	n	n	PROPN
admet-1885	230	16	ce	ce	PROPN
admet-1885	230	17	,	,	PUNCT
admet-1885	230	18	%	%	INTJ
admet-1885	230	19	admet	admet	PROPN
admet-1885	230	20	&	&	CCONJ
admet-1885	230	21	dmpk	dmpk	PROPN
admet-1885	230	22	11(4	11(4	NUM
admet-1885	230	23	)	)	PUNCT
admet-1885	230	24	(	(	PUNCT
admet-1885	230	25	2023	2023	NUM
admet-1885	230	26	)	)	PUNCT
admet-1885	230	27	533	533	NUM
admet-1885	230	28	-	-	SYM
admet-1885	230	29	550	550	NUM
admet-1885	230	30	enhancement	enhancement	NOUN
admet-1885	230	31	of	of	ADP
admet-1885	230	32	apixaban	apixaban	ADJ
admet-1885	230	33	solubility	solubility	NOUN
admet-1885	230	34	by	by	ADP
admet-1885	230	35	cyclodextrins	cyclodextrin	NOUN
admet-1885	230	36	doi	doi	PROPN
admet-1885	230	37	:	:	PUNCT
admet-1885	230	38	https://doi.org/10.5599/adme	https://doi.org/10.5599/adme	NOUN
admet-1885	230	39	t.1885	t.1885	ADP
admet-1885	230	40	543	543	NUM
admet-1885	230	41	yield	yield	NOUN
admet-1885	230	42	and	and	CCONJ
admet-1885	230	43	content	content	NOUN
admet-1885	230	44	of	of	ADP
admet-1885	230	45	ap	ap	PROPN
admet-1885	230	46	-	-	PUNCT
admet-1885	230	47	βcds	βcds	PROPN
admet-1885	230	48	inclusion	inclusion	NOUN
admet-1885	230	49	complexes	complex	NOUN
admet-1885	230	50	ap	ap	PROPN
admet-1885	230	51	-	-	PUNCT
admet-1885	230	52	βcd	βcd	NUM
admet-1885	230	53	and	and	CCONJ
admet-1885	230	54	hpβcd	hpβcd	ADJ
admet-1885	230	55	complexes	complex	NOUN
admet-1885	230	56	were	be	AUX
admet-1885	230	57	prepared	prepare	VERB
admet-1885	230	58	on	on	ADP
admet-1885	230	59	a	a	DET
admet-1885	230	60	laboratory	laboratory	NOUN
admet-1885	230	61	scale	scale	NOUN
admet-1885	230	62	.	.	PUNCT
admet-1885	231	1	however	however	ADV
admet-1885	231	2	,	,	PUNCT
admet-1885	231	3	percentage	percentage	NOUN
admet-1885	231	4	yield	yield	NOUN
admet-1885	231	5	was	be	AUX
admet-1885	231	6	important	important	ADJ
admet-1885	231	7	to	to	PART
admet-1885	231	8	determine	determine	VERB
admet-1885	231	9	how	how	SCONJ
admet-1885	231	10	efficient	efficient	ADJ
admet-1885	231	11	the	the	DET
admet-1885	231	12	method	method	NOUN
admet-1885	231	13	and	and	CCONJ
admet-1885	231	14	the	the	DET
admet-1885	231	15	skills	skill	NOUN
admet-1885	231	16	used	use	VERB
admet-1885	231	17	were	be	AUX
admet-1885	231	18	.	.	PUNCT
admet-1885	232	1	the	the	DET
admet-1885	232	2	percent	percent	NOUN
admet-1885	232	3	yield	yield	NOUN
admet-1885	232	4	of	of	ADP
admet-1885	232	5	each	each	DET
admet-1885	232	6	prepared	prepare	VERB
admet-1885	232	7	complex	complex	NOUN
admet-1885	232	8	was	be	AUX
admet-1885	232	9	calculated	calculate	VERB
admet-1885	232	10	,	,	PUNCT
admet-1885	232	11	as	as	SCONJ
admet-1885	232	12	shown	show	VERB
admet-1885	232	13	in	in	ADP
admet-1885	232	14	table	table	NOUN
admet-1885	232	15	6	6	NUM
admet-1885	232	16	.	.	PUNCT
admet-1885	233	1	all	all	DET
admet-1885	233	2	the	the	DET
admet-1885	233	3	methods	method	NOUN
admet-1885	233	4	used	use	VERB
admet-1885	233	5	were	be	AUX
admet-1885	233	6	under	under	ADP
admet-1885	233	7	good	good	ADJ
admet-1885	233	8	control	control	NOUN
admet-1885	233	9	and	and	CCONJ
admet-1885	233	10	gave	give	VERB
admet-1885	233	11	a	a	DET
admet-1885	233	12	very	very	ADV
admet-1885	233	13	high	high	ADJ
admet-1885	233	14	percent	percent	NOUN
admet-1885	233	15	yield	yield	NOUN
admet-1885	233	16	(	(	PUNCT
admet-1885	233	17	89	89	NUM
admet-1885	233	18	–	–	SYM
admet-1885	233	19	99	99	NUM
admet-1885	233	20	%	%	NOUN
admet-1885	233	21	)	)	PUNCT
admet-1885	233	22	.	.	PUNCT
admet-1885	234	1	spray	spray	NOUN
admet-1885	234	2	drying	dry	VERB
admet-1885	234	3	gave	give	VERB
admet-1885	234	4	the	the	DET
admet-1885	234	5	highest	high	ADJ
admet-1885	234	6	yield	yield	NOUN
admet-1885	234	7	with	with	ADP
admet-1885	234	8	minimum	minimum	ADJ
admet-1885	234	9	loss	loss	NOUN
admet-1885	234	10	.	.	PUNCT
admet-1885	235	1	measuring	measure	VERB
admet-1885	235	2	the	the	DET
admet-1885	235	3	content	content	NOUN
admet-1885	235	4	of	of	ADP
admet-1885	235	5	ap	ap	PROPN
admet-1885	235	6	included	include	VERB
admet-1885	235	7	in	in	ADP
admet-1885	235	8	each	each	DET
admet-1885	235	9	type	type	NOUN
admet-1885	235	10	of	of	ADP
admet-1885	235	11	the	the	DET
admet-1885	235	12	complex	complex	NOUN
admet-1885	235	13	formed	form	VERB
admet-1885	235	14	generally	generally	ADV
admet-1885	235	15	gave	give	VERB
admet-1885	235	16	a	a	DET
admet-1885	235	17	high	high	ADJ
admet-1885	235	18	loading	loading	NOUN
admet-1885	235	19	efficiency	efficiency	NOUN
admet-1885	235	20	.	.	PUNCT
admet-1885	236	1	two	two	NUM
admet-1885	236	2	variables	variable	NOUN
admet-1885	236	3	can	can	AUX
admet-1885	236	4	be	be	AUX
admet-1885	236	5	explained	explain	VERB
admet-1885	236	6	:	:	PUNCT
admet-1885	236	7	the	the	DET
admet-1885	236	8	weight	weight	NOUN
admet-1885	236	9	ratio	ratio	NOUN
admet-1885	236	10	of	of	ADP
admet-1885	236	11	ap	ap	PROPN
admet-1885	236	12	to	to	ADP
admet-1885	236	13	cd	cd	PROPN
admet-1885	236	14	and	and	CCONJ
admet-1885	236	15	the	the	DET
admet-1885	236	16	method	method	NOUN
admet-1885	236	17	of	of	ADP
admet-1885	236	18	preparation	preparation	NOUN
admet-1885	236	19	.	.	PUNCT
admet-1885	237	1	results	result	NOUN
admet-1885	237	2	in	in	ADP
admet-1885	237	3	table	table	NOUN
admet-1885	237	4	6	6	NUM
admet-1885	237	5	showed	show	VERB
admet-1885	237	6	that	that	SCONJ
admet-1885	237	7	the	the	DET
admet-1885	237	8	kneading	kneading	NOUN
admet-1885	237	9	method	method	NOUN
admet-1885	237	10	gave	give	VERB
admet-1885	237	11	the	the	DET
admet-1885	237	12	highest	high	ADJ
admet-1885	237	13	loading	loading	NOUN
admet-1885	237	14	efficiency	efficiency	NOUN
admet-1885	237	15	of	of	ADP
admet-1885	237	16	ap	ap	PROPN
admet-1885	237	17	in	in	ADP
admet-1885	237	18	the	the	DET
admet-1885	237	19	complex	complex	NOUN
admet-1885	237	20	for	for	ADP
admet-1885	237	21	both	both	DET
admet-1885	237	22	βcd	βcd	NOUN
admet-1885	237	23	and	and	CCONJ
admet-1885	237	24	hpβcd	hpβcd	ADJ
admet-1885	237	25	.	.	PUNCT
admet-1885	238	1	solvent	solvent	ADJ
admet-1885	238	2	evaporation	evaporation	NOUN
admet-1885	238	3	and	and	CCONJ
admet-1885	238	4	spray	spray	VERB
admet-1885	238	5	drying	dry	VERB
admet-1885	238	6	methods	method	NOUN
admet-1885	238	7	gave	give	VERB
admet-1885	238	8	a	a	DET
admet-1885	238	9	bit	bit	NOUN
admet-1885	238	10	less	less	ADJ
admet-1885	238	11	content	content	NOUN
admet-1885	238	12	drug	drug	NOUN
admet-1885	238	13	inclusion	inclusion	NOUN
admet-1885	238	14	.	.	PUNCT
admet-1885	239	1	this	this	DET
admet-1885	239	2	difference	difference	NOUN
admet-1885	239	3	is	be	AUX
admet-1885	239	4	attributed	attribute	VERB
admet-1885	239	5	to	to	ADP
admet-1885	239	6	the	the	DET
admet-1885	239	7	method	method	NOUN
admet-1885	239	8	of	of	ADP
admet-1885	239	9	preparation	preparation	NOUN
admet-1885	239	10	and	and	CCONJ
admet-1885	239	11	how	how	SCONJ
admet-1885	239	12	the	the	DET
admet-1885	239	13	molecule	molecule	NOUN
admet-1885	239	14	gets	get	VERB
admet-1885	239	15	inside	inside	ADP
admet-1885	239	16	the	the	DET
admet-1885	239	17	cd	cd	PROPN
admet-1885	239	18	cone	cone	NOUN
admet-1885	239	19	.	.	PUNCT
admet-1885	240	1	results	result	NOUN
admet-1885	240	2	also	also	ADV
admet-1885	240	3	showed	show	VERB
admet-1885	240	4	that	that	SCONJ
admet-1885	240	5	increasing	increase	VERB
admet-1885	240	6	the	the	DET
admet-1885	240	7	weight	weight	NOUN
admet-1885	240	8	ratio	ratio	NOUN
admet-1885	240	9	of	of	ADP
admet-1885	240	10	ap	ap	PROPN
admet-1885	240	11	from	from	ADP
admet-1885	240	12	1:1	1:1	NUM
admet-1885	240	13	to	to	ADP
admet-1885	240	14	1:2	1:2	NUM
admet-1885	240	15	,	,	PUNCT
admet-1885	240	16	both	both	PRON
admet-1885	240	17	with	with	ADP
admet-1885	240	18	βcd	βcd	NOUN
admet-1885	240	19	and	and	CCONJ
admet-1885	240	20	hpβcd	hpβcd	ADJ
admet-1885	240	21	,	,	PUNCT
admet-1885	240	22	respectively	respectively	ADV
admet-1885	240	23	,	,	PUNCT
admet-1885	240	24	increased	increase	VERB
admet-1885	240	25	the	the	DET
admet-1885	240	26	amount	amount	NOUN
admet-1885	240	27	of	of	ADP
admet-1885	240	28	drug	drug	NOUN
admet-1885	240	29	loading	loading	NOUN
admet-1885	240	30	,	,	PUNCT
admet-1885	240	31	but	but	CCONJ
admet-1885	240	32	a	a	DET
admet-1885	240	33	further	further	ADJ
admet-1885	240	34	increase	increase	NOUN
admet-1885	240	35	in	in	ADP
admet-1885	240	36	the	the	DET
admet-1885	240	37	cd	cd	PROPN
admet-1885	240	38	ratio	ratio	NOUN
admet-1885	240	39	did	do	AUX
admet-1885	240	40	not	not	PART
admet-1885	240	41	give	give	VERB
admet-1885	240	42	a	a	DET
admet-1885	240	43	noticeable	noticeable	ADJ
admet-1885	240	44	increase	increase	NOUN
admet-1885	240	45	in	in	ADP
admet-1885	240	46	the	the	DET
admet-1885	240	47	amount	amount	NOUN
admet-1885	240	48	of	of	ADP
admet-1885	240	49	drug	drug	NOUN
admet-1885	240	50	loading	loading	NOUN
admet-1885	240	51	.	.	PUNCT
admet-1885	241	1	for	for	ADP
admet-1885	241	2	that	that	DET
admet-1885	241	3	reason	reason	NOUN
admet-1885	241	4	,	,	PUNCT
admet-1885	241	5	ap	ap	PROPN
admet-1885	241	6	-	-	PUNCT
admet-1885	241	7	βcd	βcd	NOUN
admet-1885	241	8	1:2	1:2	NUM
admet-1885	241	9	and	and	CCONJ
admet-1885	241	10	ap	ap	VERB
admet-1885	241	11	-	-	PUNCT
admet-1885	241	12	hpβcd	hpβcd	ADJ
admet-1885	241	13	1:2	1:2	NUM
admet-1885	241	14	was	be	AUX
admet-1885	241	15	chosen	choose	VERB
admet-1885	241	16	for	for	ADP
admet-1885	241	17	further	further	ADJ
admet-1885	241	18	studies	study	NOUN
admet-1885	241	19	because	because	SCONJ
admet-1885	241	20	there	there	PRON
admet-1885	241	21	was	be	VERB
admet-1885	241	22	no	no	DET
admet-1885	241	23	need	need	NOUN
admet-1885	241	24	to	to	PART
admet-1885	241	25	increase	increase	VERB
admet-1885	241	26	cd	cd	NOUN
admet-1885	241	27	concentration	concentration	NOUN
admet-1885	241	28	in	in	ADP
admet-1885	241	29	the	the	DET
admet-1885	241	30	formula	formula	NOUN
admet-1885	241	31	if	if	SCONJ
admet-1885	241	32	there	there	PRON
admet-1885	241	33	was	be	VERB
admet-1885	241	34	no	no	DET
admet-1885	241	35	prominent	prominent	ADJ
admet-1885	241	36	impact	impact	NOUN
admet-1885	241	37	on	on	ADP
admet-1885	241	38	the	the	DET
admet-1885	241	39	solubility	solubility	NOUN
admet-1885	241	40	of	of	ADP
admet-1885	241	41	ap	ap	PROPN
admet-1885	241	42	.	.	PUNCT
admet-1885	241	43	table	table	PROPN
admet-1885	241	44	6	6	NUM
admet-1885	241	45	.	.	PUNCT
admet-1885	242	1	yield	yield	NOUN
admet-1885	242	2	and	and	CCONJ
admet-1885	242	3	content	content	NOUN
admet-1885	242	4	of	of	ADP
admet-1885	242	5	ap	ap	PROPN
admet-1885	242	6	-	-	PUNCT
admet-1885	242	7	βcd	βcd	NOUN
admet-1885	242	8	and	and	CCONJ
admet-1885	242	9	ap	ap	VERB
admet-1885	242	10	-	-	PUNCT
admet-1885	242	11	hpβcd	hpβcd	ADJ
admet-1885	242	12	complexes	complex	NOUN
admet-1885	242	13	.	.	PUNCT
admet-1885	243	1	method	method	NOUN
admet-1885	243	2	of	of	ADP
admet-1885	243	3	preparation	preparation	NOUN
admet-1885	243	4	type	type	NOUN
admet-1885	243	5	of	of	ADP
admet-1885	243	6	complex	complex	ADJ
admet-1885	243	7	ap	ap	PROPN
admet-1885	243	8	:	:	PUNCT
admet-1885	243	9	cd	cd	PROPN
admet-1885	243	10	weight	weight	NOUN
admet-1885	243	11	ratio	ratio	NOUN
admet-1885	243	12	yield	yield	NOUN
admet-1885	243	13	,	,	PUNCT
admet-1885	243	14	%	%	NOUN
admet-1885	243	15	loading	loading	NOUN
admet-1885	243	16	efficiency	efficiency	NOUN
admet-1885	243	17	,	,	PUNCT
admet-1885	244	1	%	%	NOUN
admet-1885	244	2	kneading	kneading	NOUN
admet-1885	244	3	βcd	βcd	VERB
admet-1885	244	4	1:1	1:1	NUM
admet-1885	244	5	91	91	NUM
admet-1885	244	6	90.6	90.6	NUM
admet-1885	244	7	kneading	kneading	NOUN
admet-1885	244	8	βcd	βcd	NOUN
admet-1885	244	9	1:2	1:2	NUM
admet-1885	244	10	93	93	NUM
admet-1885	244	11	95.5	95.5	NUM
admet-1885	244	12	kneading	kneading	NOUN
admet-1885	244	13	βcd	βcd	VERB
admet-1885	244	14	1:3	1:3	NUM
admet-1885	244	15	94	94	NUM
admet-1885	244	16	95.6	95.6	NUM
admet-1885	244	17	kneading	knead	VERB
admet-1885	244	18	hpβcd	hpβcd	INTJ
admet-1885	244	19	1:1	1:1	NUM
admet-1885	244	20	89	89	NUM
admet-1885	244	21	89.2	89.2	NUM
admet-1885	244	22	kneading	knead	VERB
admet-1885	245	1	hpβcd	hpβcd	ADJ
admet-1885	245	2	1:2	1:2	NUM
admet-1885	245	3	92.5	92.5	NUM
admet-1885	245	4	97.2	97.2	NUM
admet-1885	245	5	kneading	knead	VERB
admet-1885	245	6	hpβcd	hpβcd	INTJ
admet-1885	245	7	1:3	1:3	NUM
admet-1885	245	8	92	92	NUM
admet-1885	245	9	96.3	96.3	NUM
admet-1885	245	10	solvent	solvent	NOUN
admet-1885	245	11	evaporation	evaporation	NOUN
admet-1885	245	12	βcd	βcd	VERB
admet-1885	245	13	1:1	1:1	NUM
admet-1885	245	14	96	96	NUM
admet-1885	245	15	88	88	NUM
admet-1885	245	16	solvent	solvent	NOUN
admet-1885	245	17	evaporation	evaporation	NOUN
admet-1885	245	18	βcd	βcd	NOUN
admet-1885	245	19	1:2	1:2	NUM
admet-1885	245	20	98	98	NUM
admet-1885	245	21	93	93	NUM
admet-1885	245	22	solvent	solvent	NOUN
admet-1885	245	23	evaporation	evaporation	NOUN
admet-1885	245	24	βcd	βcd	NOUN
admet-1885	245	25	1:3	1:3	NUM
admet-1885	245	26	98	98	NUM
admet-1885	245	27	92	92	NUM
admet-1885	245	28	solvent	solvent	NOUN
admet-1885	245	29	evaporation	evaporation	NOUN
admet-1885	246	1	hpβcd	hpβcd	ADJ
admet-1885	246	2	1:1	1:1	NUM
admet-1885	246	3	95	95	NUM
admet-1885	246	4	85	85	NUM
admet-1885	246	5	solvent	solvent	NOUN
admet-1885	246	6	evaporation	evaporation	NOUN
admet-1885	246	7	hpβcd	hpβcd	ADJ
admet-1885	246	8	1:2	1:2	NUM
admet-1885	246	9	96	96	NUM
admet-1885	246	10	93	93	NUM
admet-1885	246	11	solvent	solvent	NOUN
admet-1885	246	12	evaporation	evaporation	NOUN
admet-1885	246	13	hpβcd	hpβcd	NOUN
admet-1885	246	14	1:3	1:3	NUM
admet-1885	246	15	97	97	NUM
admet-1885	246	16	92	92	NUM
admet-1885	246	17	spray	spray	NOUN
admet-1885	246	18	drying	dry	VERB
admet-1885	246	19	βcd	βcd	NUM
admet-1885	246	20	1:1	1:1	NUM
admet-1885	246	21	99	99	NUM
admet-1885	246	22	85	85	NUM
admet-1885	246	23	spray	spray	NOUN
admet-1885	246	24	drying	dry	VERB
admet-1885	246	25	βcd	βcd	NOUN
admet-1885	246	26	1:2	1:2	NUM
admet-1885	246	27	99	99	NUM
admet-1885	246	28	92	92	NUM
admet-1885	246	29	spray	spray	NOUN
admet-1885	246	30	drying	dry	VERB
admet-1885	246	31	βcd	βcd	NOUN
admet-1885	246	32	1:3	1:3	NUM
admet-1885	246	33	99	99	NUM
admet-1885	246	34	93	93	NUM
admet-1885	246	35	spray	spray	NOUN
admet-1885	246	36	drying	dry	VERB
admet-1885	246	37	hpβcd	hpβcd	ADJ
admet-1885	246	38	1:1	1:1	NUM
admet-1885	246	39	99	99	NUM
admet-1885	246	40	82	82	NUM
admet-1885	246	41	spray	spray	NOUN
admet-1885	246	42	drying	dry	VERB
admet-1885	246	43	hpβcd	hpβcd	PROPN
admet-1885	246	44	1:2	1:2	NUM
admet-1885	246	45	99	99	NUM
admet-1885	246	46	94	94	NUM
admet-1885	246	47	spray	spray	NOUN
admet-1885	246	48	drying	dry	VERB
admet-1885	246	49	hpβcd	hpβcd	PROPN
admet-1885	246	50	1:3	1:3	NUM
admet-1885	246	51	99	99	NUM
admet-1885	246	52	95	95	NUM
admet-1885	246	53	characterization	characterization	NOUN
admet-1885	246	54	of	of	ADP
admet-1885	246	55	ap	ap	PROPN
admet-1885	246	56	-	-	PUNCT
admet-1885	246	57	βcd	βcd	NOUN
admet-1885	246	58	(	(	PUNCT
admet-1885	246	59	1:2	1:2	NUM
admet-1885	246	60	)	)	PUNCT
admet-1885	246	61	and	and	CCONJ
admet-1885	246	62	ap	ap	VERB
admet-1885	246	63	-	-	PUNCT
admet-1885	246	64	hpβcd	hpβcd	ADJ
admet-1885	246	65	(	(	PUNCT
admet-1885	246	66	1:2	1:2	NUM
admet-1885	246	67	)	)	PUNCT
admet-1885	246	68	complex	complex	NOUN
admet-1885	246	69	by	by	ADP
admet-1885	246	70	dsc	dsc	NOUN
admet-1885	246	71	further	further	ADJ
admet-1885	246	72	characterization	characterization	NOUN
admet-1885	246	73	of	of	ADP
admet-1885	246	74	ap	ap	VERB
admet-1885	246	75	-	-	PUNCT
admet-1885	246	76	hpβcd	hpβcd	ADJ
admet-1885	246	77	(	(	PUNCT
admet-1885	246	78	1:2	1:2	NUM
admet-1885	246	79	)	)	PUNCT
admet-1885	246	80	complex	complex	NOUN
admet-1885	246	81	was	be	AUX
admet-1885	246	82	done	do	VERB
admet-1885	246	83	by	by	ADP
admet-1885	246	84	dsc	dsc	NOUN
admet-1885	246	85	for	for	ADP
admet-1885	246	86	further	further	ADJ
admet-1885	246	87	confirmation	confirmation	NOUN
admet-1885	246	88	.	.	PUNCT
admet-1885	247	1	results	result	NOUN
admet-1885	247	2	are	be	AUX
admet-1885	247	3	shown	show	VERB
admet-1885	247	4	in	in	ADP
admet-1885	247	5	figure	figure	NOUN
admet-1885	247	6	6	6	NUM
admet-1885	247	7	a	a	DET
admet-1885	247	8	(	(	PUNCT
admet-1885	247	9	ap	ap	PROPN
admet-1885	247	10	)	)	PUNCT
admet-1885	247	11	,	,	PUNCT
admet-1885	247	12	-b	-b	PUNCT
admet-1885	247	13	(	(	PUNCT
admet-1885	247	14	hpβcd	hpβcd	ADJ
admet-1885	247	15	)	)	PUNCT
admet-1885	247	16	,	,	PUNCT
admet-1885	247	17	and	and	CCONJ
admet-1885	247	18	-c	-c	X
admet-1885	247	19	(	(	PUNCT
admet-1885	247	20	ap	ap	VERB
admet-1885	247	21	-	-	PUNCT
admet-1885	247	22	hpβcd	hpβcd	PROPN
admet-1885	247	23	1:2	1:2	NUM
admet-1885	247	24	complex	complex	NOUN
admet-1885	247	25	)	)	PUNCT
admet-1885	247	26	,	,	PUNCT
admet-1885	247	27	which	which	PRON
admet-1885	247	28	was	be	AUX
admet-1885	247	29	chosen	choose	VERB
admet-1885	247	30	for	for	ADP
admet-1885	247	31	the	the	DET
admet-1885	247	32	formulation	formulation	NOUN
admet-1885	247	33	of	of	ADP
admet-1885	247	34	the	the	DET
admet-1885	247	35	capsules	capsule	NOUN
admet-1885	247	36	.	.	PUNCT
admet-1885	248	1	results	result	NOUN
admet-1885	248	2	show	show	VERB
admet-1885	248	3	the	the	DET
admet-1885	248	4	melting	melting	NOUN
admet-1885	248	5	point	point	NOUN
admet-1885	248	6	of	of	ADP
admet-1885	248	7	ap	ap	PROPN
admet-1885	248	8	of	of	ADP
admet-1885	248	9	approximately	approximately	ADV
admet-1885	248	10	220	220	NUM
admet-1885	249	1	°	°	NOUN
admet-1885	249	2	c	c	NOUN
admet-1885	249	3	from	from	ADP
admet-1885	249	4	dsc	dsc	PROPN
admet-1885	249	5	.	.	PUNCT
admet-1885	250	1	figure	figure	VERB
admet-1885	250	2	6	6	NUM
admet-1885	250	3	b	b	NOUN
admet-1885	250	4	also	also	ADV
admet-1885	250	5	shows	show	VERB
admet-1885	250	6	the	the	DET
admet-1885	250	7	dcs	dcs	PROPN
admet-1885	250	8	thermogram	thermogram	PROPN
admet-1885	250	9	of	of	ADP
admet-1885	250	10	hpβcd	hpβcd	ADV
admet-1885	250	11	showing	show	VERB
admet-1885	250	12	a	a	DET
admet-1885	250	13	broad	broad	ADJ
admet-1885	250	14	peak	peak	NOUN
admet-1885	250	15	in	in	ADP
admet-1885	250	16	the	the	DET
admet-1885	250	17	range	range	NOUN
admet-1885	250	18	280	280	NUM
admet-1885	250	19	–	–	SYM
admet-1885	250	20	340	340	NUM
admet-1885	251	1	°	°	SYM
admet-1885	251	2	c	c	NOUN
admet-1885	251	3	.	.	PUNCT
admet-1885	252	1	the	the	DET
admet-1885	252	2	complex	complex	ADJ
admet-1885	252	3	thermogram	thermogram	NOUN
admet-1885	252	4	shows	show	VERB
admet-1885	252	5	that	that	SCONJ
admet-1885	252	6	the	the	DET
admet-1885	252	7	sharp	sharp	ADJ
admet-1885	252	8	peak	peak	NOUN
admet-1885	252	9	of	of	ADP
admet-1885	252	10	ap	ap	PROPN
admet-1885	252	11	is	be	AUX
admet-1885	252	12	embedded	embed	VERB
admet-1885	252	13	in	in	ADP
admet-1885	252	14	the	the	DET
admet-1885	252	15	hpβcd	hpβcd	NOUN
admet-1885	252	16	and	and	CCONJ
admet-1885	252	17	is	be	AUX
admet-1885	252	18	not	not	PART
admet-1885	252	19	clearly	clearly	ADV
admet-1885	252	20	distinguished	distinguish	VERB
admet-1885	252	21	,	,	PUNCT
admet-1885	252	22	indicating	indicate	VERB
admet-1885	252	23	the	the	DET
admet-1885	252	24	formation	formation	NOUN
admet-1885	252	25	of	of	ADP
admet-1885	252	26	an	an	DET
admet-1885	252	27	inclusion	inclusion	NOUN
admet-1885	252	28	complex	complex	NOUN
admet-1885	252	29	between	between	ADP
admet-1885	252	30	ap	ap	PROPN
admet-1885	252	31	and	and	CCONJ
admet-1885	252	32	hpβcd	hpβcd	INTJ
admet-1885	252	33	(	(	PUNCT
admet-1885	252	34	c	c	NOUN
admet-1885	252	35	)	)	PUNCT
admet-1885	252	36	.	.	PUNCT
admet-1885	253	1	phase	phase	NOUN
admet-1885	253	2	solubility	solubility	NOUN
admet-1885	253	3	analysis	analysis	NOUN
admet-1885	253	4	of	of	ADP
admet-1885	253	5	ap	ap	PROPN
admet-1885	253	6	-	-	PUNCT
admet-1885	253	7	βcd	βcd	NOUN
admet-1885	253	8	and	and	CCONJ
admet-1885	253	9	ap	ap	VERB
admet-1885	253	10	-	-	PUNCT
admet-1885	253	11	hpβcd	hpβcd	VERB
admet-1885	253	12	inclusion	inclusion	NOUN
admet-1885	253	13	complexes	complexe	VERB
admet-1885	253	14	the	the	DET
admet-1885	253	15	phase	phase	NOUN
admet-1885	253	16	solubility	solubility	NOUN
admet-1885	253	17	profile	profile	NOUN
admet-1885	253	18	of	of	ADP
admet-1885	253	19	ap	ap	VERB
admet-1885	253	20	-	-	PUNCT
admet-1885	253	21	hpβcd	hpβcd	PROPN
admet-1885	253	22	is	be	AUX
admet-1885	253	23	presented	present	VERB
admet-1885	253	24	in	in	ADP
admet-1885	253	25	figure	figure	NOUN
admet-1885	253	26	7	7	NUM
admet-1885	253	27	.	.	PUNCT
admet-1885	254	1	the	the	DET
admet-1885	254	2	solubility	solubility	NOUN
admet-1885	254	3	of	of	ADP
admet-1885	254	4	pure	pure	ADJ
admet-1885	254	5	ap	ap	PROPN
admet-1885	254	6	was	be	AUX
admet-1885	254	7	calculated	calculate	VERB
admet-1885	254	8	approximately	approximately	ADV
admet-1885	254	9	as	as	SCONJ
admet-1885	254	10	54.4x10	54.4x10	NUM
admet-1885	254	11	-	-	SYM
admet-1885	254	12	3	3	NUM
admet-1885	254	13	mmol	mmol	NOUN
admet-1885	254	14	(	(	PUNCT
admet-1885	254	15	25	25	NUM
admet-1885	254	16	µg	µg	NOUN
admet-1885	254	17	/	/	SYM
admet-1885	254	18	ml	ml	NOUN
admet-1885	254	19	)	)	PUNCT
admet-1885	254	20	(	(	PUNCT
admet-1885	254	21	28	28	NUM
admet-1885	254	22	µg	µg	NOUN
admet-1885	254	23	/	/	SYM
admet-1885	254	24	ml	ml	NOUN
admet-1885	254	25	reported	report	VERB
admet-1885	254	26	by	by	ADP
admet-1885	254	27	[	[	X
admet-1885	254	28	22	22	NUM
admet-1885	254	29	]	]	PUNCT
admet-1885	254	30	)	)	PUNCT
admet-1885	254	31	.	.	PUNCT
admet-1885	255	1	using	use	VERB
admet-1885	255	2	suitable	suitable	ADJ
admet-1885	255	3	dilutions	dilution	NOUN
admet-1885	255	4	,	,	PUNCT
admet-1885	255	5	concentrations	concentration	NOUN
admet-1885	255	6	,	,	PUNCT
admet-1885	255	7	mol	mol	NOUN
admet-1885	255	8	/	/	SYM
admet-1885	255	9	l	l	NOUN
admet-1885	255	10	of	of	ADP
admet-1885	255	11	solubilized	solubilize	VERB
admet-1885	255	12	ap	ap	PROPN
admet-1885	255	13	by	by	ADP
admet-1885	255	14	different	different	ADJ
admet-1885	255	15	concentrations	concentration	NOUN
admet-1885	255	16	of	of	ADP
admet-1885	255	17	hpβcd	hpβcd	PROPN
admet-1885	255	18	were	be	AUX
admet-1885	255	19	calculated	calculate	VERB
admet-1885	255	20	and	and	CCONJ
admet-1885	255	21	given	give	VERB
admet-1885	255	22	in	in	ADP
admet-1885	255	23	table	table	NOUN
admet-1885	255	24	7	7	NUM
admet-1885	255	25	.	.	NOUN
admet-1885	255	26	https://doi.org/10.5599/admet.1885	https://doi.org/10.5599/admet.1885	PROPN
admet-1885	255	27	z.	z.	PROPN
admet-1885	255	28	n.	n.	PROPN
admet-1885	255	29	salman	salman	PROPN
admet-1885	255	30	et	et	PROPN
admet-1885	255	31	al	al	PROPN
admet-1885	255	32	.	.	PROPN
admet-1885	255	33	admet	admet	PROPN
admet-1885	255	34	&	&	CCONJ
admet-1885	255	35	dmpk	dmpk	PROPN
admet-1885	255	36	11(4	11(4	NUM
admet-1885	255	37	)	)	PUNCT
admet-1885	255	38	(	(	PUNCT
admet-1885	255	39	2023	2023	NUM
admet-1885	255	40	)	)	PUNCT
admet-1885	256	1	533	533	NUM
admet-1885	256	2	-	-	SYM
admet-1885	256	3	550	550	NUM
admet-1885	256	4	544	544	NUM
admet-1885	256	5	figure	figure	NOUN
admet-1885	256	6	6	6	NUM
admet-1885	256	7	.	.	PUNCT
admet-1885	256	8	dsc	dsc	NOUN
admet-1885	256	9	thermograms	thermogram	NOUN
admet-1885	256	10	of	of	ADP
admet-1885	256	11	ap	ap	PROPN
admet-1885	256	12	(	(	PUNCT
admet-1885	256	13	a	a	PROPN
admet-1885	256	14	)	)	PUNCT
admet-1885	256	15	,	,	PUNCT
admet-1885	256	16	hpβcd	hpβcd	X
admet-1885	256	17	(	(	PUNCT
admet-1885	256	18	b	b	NOUN
admet-1885	256	19	)	)	PUNCT
admet-1885	256	20	and	and	CCONJ
admet-1885	256	21	ap	ap	VERB
admet-1885	256	22	-	-	PUNCT
admet-1885	256	23	hpβcd	hpβcd	VERB
admet-1885	256	24	complex	complex	ADJ
admet-1885	256	25	ratio	ratio	NOUN
admet-1885	256	26	(	(	PUNCT
admet-1885	256	27	ap	ap	PROPN
admet-1885	256	28	:	:	PUNCT
admet-1885	256	29	hpβcd	hpβcd	NUM
admet-1885	256	30	)	)	PUNCT
admet-1885	256	31	(	(	PUNCT
admet-1885	256	32	1:2	1:2	NUM
admet-1885	256	33	w	w	PROPN
admet-1885	256	34	/	/	SYM
admet-1885	256	35	w	w	NOUN
admet-1885	256	36	)	)	PUNCT
admet-1885	256	37	(	(	PUNCT
admet-1885	256	38	c	c	NOUN
admet-1885	256	39	)	)	PUNCT
admet-1885	256	40	.	.	PUNCT
admet-1885	257	1	admet	admet	PROPN
admet-1885	257	2	&	&	CCONJ
admet-1885	257	3	dmpk	dmpk	PROPN
admet-1885	257	4	11(4	11(4	NUM
admet-1885	257	5	)	)	PUNCT
admet-1885	257	6	(	(	PUNCT
admet-1885	257	7	2023	2023	NUM
admet-1885	257	8	)	)	PUNCT
admet-1885	257	9	533	533	NUM
admet-1885	257	10	-	-	SYM
admet-1885	257	11	550	550	NUM
admet-1885	257	12	enhancement	enhancement	NOUN
admet-1885	257	13	of	of	ADP
admet-1885	257	14	apixaban	apixaban	ADJ
admet-1885	257	15	solubility	solubility	NOUN
admet-1885	257	16	by	by	ADP
admet-1885	257	17	cyclodextrins	cyclodextrin	NOUN
admet-1885	257	18	doi	doi	PROPN
admet-1885	257	19	:	:	PUNCT
admet-1885	257	20	https://doi.org/10.5599/adme	https://doi.org/10.5599/adme	NOUN
admet-1885	257	21	t.1885	t.1885	ADP
admet-1885	257	22	545	545	NUM
admet-1885	257	23	table	table	NOUN
admet-1885	257	24	7	7	NUM
admet-1885	257	25	.	.	PUNCT
admet-1885	257	26	results	result	NOUN
admet-1885	257	27	of	of	ADP
admet-1885	257	28	phase	phase	NOUN
admet-1885	257	29	solubility	solubility	NOUN
admet-1885	257	30	study	study	NOUN
admet-1885	257	31	.	.	PUNCT
admet-1885	258	1	c	c	NOUN
admet-1885	258	2	/	/	SYM
admet-1885	258	3	mmol	mmol	PROPN
admet-1885	258	4	l-1	l-1	NOUN
admet-1885	258	5	hpβcd	hpβcd	PROPN
admet-1885	258	6	soluble	soluble	PROPN
admet-1885	258	7	ap	ap	PROPN
admet-1885	258	8	soluble	soluble	PROPN
admet-1885	258	9	ap	ap	PROPN
admet-1885	259	1	total	total	ADJ
admet-1885	259	2	s0	s0	PROPN
admet-1885	259	3	+	+	PROPN
admet-1885	259	4	scomplex	scomplex	ADJ
admet-1885	259	5	soluble	soluble	ADJ
admet-1885	259	6	ap	ap	PROPN
admet-1885	259	7	,	,	PUNCT
admet-1885	259	8	by	by	ADP
admet-1885	259	9	hpβcd	hpβcd	ADJ
admet-1885	259	10	4.0	4.0	NUM
admet-1885	259	11	30.621	30.621	NUM
admet-1885	259	12	66.6764	66.6764	NUM
admet-1885	259	13	66.622	66.622	NUM
admet-1885	259	14	10	10	NUM
admet-1885	259	15	.0	.0	NUM
admet-1885	259	16	30.781	30.781	NUM
admet-1885	259	17	66.8434	66.8434	NUM
admet-1885	259	18	66.789	66.789	NUM
admet-1885	259	19	15.0	15.0	NUM
admet-1885	259	20	30.871	30.871	NUM
admet-1885	259	21	67.1904	67.1904	NUM
admet-1885	259	22	67.185	67.185	NUM
admet-1885	259	23	20.0	20.0	NUM
admet-1885	259	24	30.971	30.971	NUM
admet-1885	259	25	67.4084	67.4084	NUM
admet-1885	259	26	67.403	67.403	NUM
admet-1885	259	27	chpcd	chpcd	PROPN
admet-1885	259	28	/	/	SYM
admet-1885	259	29	mm	mm	PROPN
admet-1885	259	30	l-1	l-1	NOUN
admet-1885	259	31	figure	figure	NOUN
admet-1885	259	32	7	7	NUM
admet-1885	259	33	.	.	NOUN
admet-1885	259	34	phase	phase	NOUN
admet-1885	259	35	solubility	solubility	NOUN
admet-1885	259	36	diagram	diagram	NOUN
admet-1885	259	37	of	of	ADP
admet-1885	259	38	ap	ap	PROPN
admet-1885	259	39	with	with	ADP
admet-1885	259	40	hpβcd	hpβcd	PROPN
admet-1885	259	41	.	.	PUNCT
admet-1885	260	1	from	from	ADP
admet-1885	260	2	figure	figure	NOUN
admet-1885	260	3	7	7	NUM
admet-1885	260	4	,	,	PUNCT
admet-1885	260	5	the	the	DET
admet-1885	260	6	solubility	solubility	NOUN
admet-1885	260	7	of	of	ADP
admet-1885	260	8	ap	ap	PROPN
admet-1885	260	9	increased	increase	VERB
admet-1885	260	10	proportionally	proportionally	ADV
admet-1885	260	11	with	with	ADP
admet-1885	260	12	an	an	DET
admet-1885	260	13	increase	increase	NOUN
admet-1885	260	14	in	in	ADP
admet-1885	260	15	the	the	DET
admet-1885	260	16	concentration	concentration	NOUN
admet-1885	260	17	of	of	ADP
admet-1885	260	18	hpβcd	hpβcd	PROPN
admet-1885	260	19	(	(	PUNCT
admet-1885	260	20	r2	r2	PROPN
admet-1885	260	21	=	=	NOUN
admet-1885	260	22	0.97	0.97	NUM
admet-1885	260	23	)	)	PUNCT
admet-1885	260	24	.	.	PUNCT
admet-1885	261	1	however	however	ADV
admet-1885	261	2	,	,	PUNCT
admet-1885	261	3	the	the	DET
admet-1885	261	4	increase	increase	NOUN
admet-1885	261	5	of	of	ADP
admet-1885	261	6	molar	molar	ADJ
admet-1885	261	7	concentration	concentration	NOUN
admet-1885	261	8	of	of	ADP
admet-1885	261	9	hpβcd	hpβcd	NUM
admet-1885	261	10	from	from	ADP
admet-1885	261	11	4	4	NUM
admet-1885	261	12	20	20	NUM
admet-1885	261	13	(	(	PUNCT
admet-1885	261	14	5	5	NUM
admet-1885	261	15	folds	fold	NOUN
admet-1885	261	16	)	)	PUNCT
admet-1885	261	17	resulted	result	VERB
admet-1885	261	18	in	in	ADP
admet-1885	261	19	a	a	DET
admet-1885	261	20	very	very	ADV
admet-1885	261	21	slight	slight	ADJ
admet-1885	261	22	increase	increase	NOUN
admet-1885	261	23	in	in	ADP
admet-1885	261	24	the	the	DET
admet-1885	261	25	solubility	solubility	NOUN
admet-1885	261	26	of	of	ADP
admet-1885	261	27	ap	ap	PROPN
admet-1885	261	28	.	.	PROPN
admet-1885	262	1	1:1	1:1	NUM
admet-1885	263	1	relation	relation	NOUN
admet-1885	263	2	means	mean	VERB
admet-1885	263	3	that	that	SCONJ
admet-1885	263	4	every	every	DET
admet-1885	263	5	molecule	molecule	NOUN
admet-1885	263	6	of	of	ADP
admet-1885	263	7	the	the	DET
admet-1885	263	8	host	host	NOUN
admet-1885	263	9	compound	compound	NOUN
admet-1885	263	10	incorporates	incorporate	VERB
admet-1885	263	11	one	one	NUM
admet-1885	263	12	molecule	molecule	NOUN
admet-1885	263	13	of	of	ADP
admet-1885	263	14	the	the	DET
admet-1885	263	15	guest	guest	NOUN
admet-1885	263	16	(	(	PUNCT
admet-1885	263	17	ap	ap	PROPN
admet-1885	263	18	)	)	PUNCT
admet-1885	263	19	.	.	PUNCT
admet-1885	264	1	the	the	DET
admet-1885	264	2	lowest	low	ADJ
admet-1885	264	3	concentration	concentration	NOUN
admet-1885	264	4	of	of	ADP
admet-1885	264	5	hpβcd	hpβcd	ADJ
admet-1885	264	6	used	use	VERB
admet-1885	264	7	(	(	PUNCT
admet-1885	264	8	4	4	NUM
admet-1885	264	9	mm	mm	NOUN
admet-1885	264	10	)	)	PUNCT
admet-1885	264	11	resulted	result	VERB
admet-1885	264	12	in	in	ADP
admet-1885	264	13	1224	1224	NUM
admet-1885	264	14	fold	fold	NOUN
admet-1885	264	15	increase	increase	NOUN
admet-1885	264	16	in	in	ADP
admet-1885	264	17	the	the	DET
admet-1885	264	18	solubility	solubility	NOUN
admet-1885	264	19	of	of	ADP
admet-1885	264	20	ap	ap	PROPN
admet-1885	264	21	in	in	ADP
admet-1885	264	22	water	water	NOUN
admet-1885	264	23	(	(	PUNCT
admet-1885	264	24	from	from	ADP
admet-1885	264	25	54.4	54.4	NUM
admet-1885	264	26	µm	µm	NOUN
admet-1885	264	27	to	to	ADP
admet-1885	264	28	66.622	66.622	NUM
admet-1885	264	29	mm	mm	NOUN
admet-1885	264	30	)	)	PUNCT
admet-1885	264	31	.	.	PUNCT
admet-1885	265	1	further	far	ADV
admet-1885	265	2	increase	increase	VERB
admet-1885	265	3	in	in	ADP
admet-1885	265	4	hpβcd	hpβcd	NUM
admet-1885	265	5	resulted	result	VERB
admet-1885	265	6	in	in	ADP
admet-1885	265	7	a	a	DET
admet-1885	265	8	slight	slight	ADJ
admet-1885	265	9	increase	increase	NOUN
admet-1885	265	10	in	in	ADP
admet-1885	265	11	solubility	solubility	NOUN
admet-1885	265	12	.	.	PUNCT
admet-1885	266	1	however	however	ADV
admet-1885	266	2	,	,	PUNCT
admet-1885	266	3	a	a	DET
admet-1885	266	4	straight	straight	ADJ
admet-1885	266	5	line	line	NOUN
admet-1885	266	6	with	with	ADP
admet-1885	266	7	a	a	DET
admet-1885	266	8	good	good	ADJ
admet-1885	266	9	correlation	correlation	NOUN
admet-1885	266	10	was	be	AUX
admet-1885	266	11	obtained	obtain	VERB
admet-1885	266	12	in	in	ADP
admet-1885	266	13	figure	figure	NOUN
admet-1885	266	14	7	7	NUM
admet-1885	266	15	,	,	PUNCT
admet-1885	266	16	and	and	CCONJ
admet-1885	266	17	the	the	DET
admet-1885	266	18	stability	stability	NOUN
admet-1885	266	19	constant	constant	ADJ
admet-1885	266	20	was	be	AUX
admet-1885	266	21	calculated	calculate	VERB
admet-1885	266	22	by	by	ADP
admet-1885	266	23	equations	equation	NOUN
admet-1885	266	24	(	(	PUNCT
admet-1885	266	25	3	3	NUM
admet-1885	266	26	)	)	PUNCT
admet-1885	266	27	and	and	CCONJ
admet-1885	266	28	(	(	PUNCT
admet-1885	266	29	4	4	NUM
admet-1885	266	30	)	)	PUNCT
admet-1885	266	31	:	:	PUNCT
admet-1885	266	32	(	(	PUNCT
admet-1885	266	33	)	)	PUNCT
admet-1885	266	34	st	st	PROPN
admet-1885	266	35	0	0	NUM
admet-1885	266	36	slope	slope	NOUN
admet-1885	266	37	  	  	SPACE
admet-1885	266	38	1	1	NUM
admet-1885	266	39	-	-	PUNCT
admet-1885	266	40	slope	slope	NOUN
admet-1885	266	41	k	k	X
admet-1885	266	42	s	s	NOUN
admet-1885	266	43	=	=	X
admet-1885	266	44	(	(	PUNCT
admet-1885	266	45	3	3	NUM
admet-1885	266	46	)	)	PUNCT
admet-1885	266	47	(	(	PUNCT
admet-1885	266	48	)	)	PUNCT
admet-1885	266	49	st	st	PROPN
admet-1885	267	1	0.0513	0.0513	NUM
admet-1885	267	2	0.0544	0.0544	NUM
admet-1885	267	3	1	1	NUM
admet-1885	267	4	0.0513	0.0513	NUM
admet-1885	267	5	k	k	NOUN
admet-1885	267	6	−	−	NOUN
admet-1885	268	1	=	=	PUNCT
admet-1885	268	2	994.2	994.2	NUM
admet-1885	268	3	m-1	m-1	NOUN
admet-1885	268	4	(	(	PUNCT
admet-1885	268	5	4	4	X
admet-1885	268	6	)	)	PUNCT
admet-1885	268	7	the	the	DET
admet-1885	268	8	stability	stability	NOUN
admet-1885	268	9	constant	constant	ADJ
admet-1885	268	10	(	(	PUNCT
admet-1885	268	11	kst	kst	X
admet-1885	268	12	)	)	PUNCT
admet-1885	268	13	equals	equal	VERB
admet-1885	268	14	994.2	994.2	NUM
admet-1885	268	15	m-1	m-1	NOUN
admet-1885	268	16	.	.	PUNCT
admet-1885	269	1	it	it	PRON
admet-1885	269	2	was	be	AUX
admet-1885	269	3	reported	report	VERB
admet-1885	269	4	that	that	SCONJ
admet-1885	269	5	ks	ks	NOUN
admet-1885	269	6	value	value	NOUN
admet-1885	269	7	between	between	ADP
admet-1885	269	8	50	50	NUM
admet-1885	269	9	and	and	CCONJ
admet-1885	269	10	5000	5000	NUM
admet-1885	269	11	m−1	m−1	PROPN
admet-1885	269	12	was	be	AUX
admet-1885	269	13	considered	consider	VERB
admet-1885	269	14	the	the	DET
admet-1885	269	15	most	most	ADV
admet-1885	269	16	suitable	suitable	ADJ
admet-1885	269	17	for	for	ADP
admet-1885	269	18	the	the	DET
admet-1885	269	19	improvement	improvement	NOUN
admet-1885	269	20	of	of	ADP
admet-1885	269	21	solubility	solubility	NOUN
admet-1885	269	22	and	and	CCONJ
admet-1885	269	23	stability	stability	NOUN
admet-1885	269	24	of	of	ADP
admet-1885	269	25	poorly	poorly	ADV
admet-1885	269	26	soluble	soluble	ADJ
admet-1885	269	27	drugs	drug	NOUN
admet-1885	269	28	[	[	X
admet-1885	269	29	23	23	NUM
admet-1885	269	30	]	]	PUNCT
admet-1885	269	31	.	.	PUNCT
admet-1885	270	1	in	in	ADP
admet-1885	270	2	conclusion	conclusion	NOUN
admet-1885	270	3	,	,	PUNCT
admet-1885	270	4	hpβcd	hpβcd	INTJ
admet-1885	270	5	increased	increase	VERB
admet-1885	270	6	the	the	DET
admet-1885	270	7	solubility	solubility	NOUN
admet-1885	270	8	of	of	ADP
admet-1885	270	9	ap	ap	PROPN
admet-1885	270	10	significantly	significantly	ADV
admet-1885	270	11	with	with	ADP
admet-1885	270	12	good	good	ADJ
admet-1885	270	13	stability	stability	NOUN
admet-1885	270	14	of	of	ADP
admet-1885	270	15	the	the	DET
admet-1885	270	16	complex	complex	NOUN
admet-1885	270	17	in	in	ADP
admet-1885	270	18	a	a	DET
admet-1885	270	19	ratio	ratio	NOUN
admet-1885	270	20	1:1	1:1	NUM
admet-1885	270	21	host	host	NOUN
admet-1885	270	22	-	-	PUNCT
admet-1885	270	23	guest	guest	NOUN
admet-1885	270	24	molecules	molecule	NOUN
admet-1885	270	25	.	.	PUNCT
admet-1885	271	1	computer	computer	NOUN
admet-1885	271	2	calculations	calculation	NOUN
admet-1885	271	3	docking	docking	NOUN
admet-1885	271	4	calculations	calculation	NOUN
admet-1885	271	5	offer	offer	VERB
admet-1885	271	6	essential	essential	ADJ
admet-1885	271	7	information	information	NOUN
admet-1885	271	8	regarding	regard	VERB
admet-1885	271	9	the	the	DET
admet-1885	271	10	conformation	conformation	NOUN
admet-1885	271	11	of	of	ADP
admet-1885	271	12	the	the	DET
admet-1885	271	13	guest	guest	NOUN
admet-1885	271	14	-	-	PUNCT
admet-1885	271	15	host	host	NOUN
admet-1885	271	16	complexes	complex	NOUN
admet-1885	271	17	and	and	CCONJ
admet-1885	271	18	produce	produce	VERB
admet-1885	271	19	a	a	DET
admet-1885	271	20	quantitative	quantitative	ADJ
admet-1885	271	21	parameter	parameter	NOUN
admet-1885	271	22	of	of	ADP
admet-1885	271	23	the	the	DET
admet-1885	271	24	binding	bind	VERB
admet-1885	271	25	affinity	affinity	NOUN
admet-1885	271	26	of	of	ADP
admet-1885	271	27	different	different	ADJ
admet-1885	271	28	complexes	complex	NOUN
admet-1885	271	29	.	.	PUNCT
admet-1885	272	1	ap	ap	PROPN
admet-1885	272	2	has	have	AUX
admet-1885	272	3	shown	show	VERB
admet-1885	272	4	the	the	DET
admet-1885	272	5	highest	high	ADJ
admet-1885	272	6	binding	bind	VERB
admet-1885	272	7	affinity	affinity	NOUN
admet-1885	272	8	in	in	ADP
admet-1885	272	9	complexing	complexe	VERB
admet-1885	272	10	with	with	ADP
admet-1885	272	11	hpβcd	hpβcd	PROPN
admet-1885	272	12	(	(	PUNCT
admet-1885	272	13	-7.62	-7.62	NUM
admet-1885	272	14	kcal	kcal	PROPN
admet-1885	272	15	/	/	SYM
admet-1885	272	16	mol	mol	NOUN
admet-1885	272	17	)	)	PUNCT
admet-1885	272	18	followed	follow	VERB
admet-1885	272	19	by	by	ADP
admet-1885	272	20	βcd	βcd	PROPN
admet-1885	272	21	(	(	PUNCT
admet-1885	272	22	-6.81	-6.81	NOUN
admet-1885	272	23	kcal	kcal	PROPN
admet-1885	272	24	/	/	SYM
admet-1885	272	25	mol	mol	NOUN
admet-1885	272	26	)	)	PUNCT
admet-1885	272	27	,	,	PUNCT
admet-1885	272	28	where	where	SCONJ
admet-1885	272	29	it	it	PRON
admet-1885	272	30	agrees	agree	VERB
admet-1885	272	31	with	with	ADP
admet-1885	272	32	the	the	DET
admet-1885	272	33	experimental	experimental	ADJ
admet-1885	272	34	part	part	NOUN
admet-1885	272	35	attained	attain	VERB
admet-1885	272	36	.	.	PUNCT
admet-1885	273	1	c	c	PROPN
admet-1885	273	2	s	s	VERB
admet-1885	273	3	ol	ol	PROPN
admet-1885	273	4	ub	ub	INTJ
admet-1885	273	5	ile	ile	PROPN
admet-1885	273	6	a	a	DET
admet-1885	273	7	p	p	PROPN
admet-1885	273	8	,	,	PUNCT
admet-1885	273	9	m	m	VERB
admet-1885	273	10	m	m	VERB
admet-1885	273	11	l	l	NOUN
admet-1885	273	12	-1	-1	NOUN
admet-1885	273	13	,	,	PUNCT
admet-1885	273	14	%	%	NOUN
admet-1885	273	15	https://doi.org/10.5599/admet.1885	https://doi.org/10.5599/admet.1885	X
admet-1885	274	1	z.	z.	PROPN
admet-1885	274	2	n.	n.	PROPN
admet-1885	274	3	salman	salman	PROPN
admet-1885	274	4	et	et	PROPN
admet-1885	274	5	al	al	PROPN
admet-1885	274	6	.	.	PROPN
admet-1885	274	7	admet	admet	PROPN
admet-1885	274	8	&	&	CCONJ
admet-1885	274	9	dmpk	dmpk	PROPN
admet-1885	274	10	11(4	11(4	NUM
admet-1885	274	11	)	)	PUNCT
admet-1885	274	12	(	(	PUNCT
admet-1885	274	13	2023	2023	NUM
admet-1885	274	14	)	)	PUNCT
admet-1885	274	15	533	533	NUM
admet-1885	274	16	-	-	SYM
admet-1885	274	17	550	550	NUM
admet-1885	274	18	546	546	NUM
admet-1885	274	19	figures	figure	NOUN
admet-1885	274	20	8	8	NUM
admet-1885	274	21	and	and	CCONJ
admet-1885	274	22	9	9	NUM
admet-1885	274	23	give	give	VERB
admet-1885	274	24	better	well	ADJ
admet-1885	274	25	insight	insight	NOUN
admet-1885	274	26	into	into	ADP
admet-1885	274	27	the	the	DET
admet-1885	274	28	binding	bind	VERB
admet-1885	274	29	interaction	interaction	NOUN
admet-1885	274	30	between	between	ADP
admet-1885	274	31	the	the	DET
admet-1885	274	32	host	host	NOUN
admet-1885	274	33	-	-	PUNCT
admet-1885	274	34	guest	guest	NOUN
admet-1885	274	35	complexes	complex	NOUN
admet-1885	274	36	.	.	PUNCT
admet-1885	275	1	in	in	ADP
admet-1885	275	2	both	both	DET
admet-1885	275	3	cases	case	NOUN
admet-1885	275	4	,	,	PUNCT
admet-1885	275	5	the	the	DET
admet-1885	275	6	amide	amide	NOUN
admet-1885	275	7	group	group	NOUN
admet-1885	275	8	is	be	AUX
admet-1885	275	9	included	include	VERB
admet-1885	275	10	inside	inside	ADP
admet-1885	275	11	the	the	DET
admet-1885	275	12	cone	cone	NOUN
admet-1885	275	13	.	.	PUNCT
admet-1885	276	1	the	the	DET
admet-1885	276	2	same	same	ADJ
admet-1885	276	3	result	result	NOUN
admet-1885	276	4	was	be	AUX
admet-1885	276	5	obtained	obtain	VERB
admet-1885	276	6	from	from	ADP
admet-1885	276	7	the	the	DET
admet-1885	276	8	ftir	ftir	ADJ
admet-1885	276	9	analysis	analysis	NOUN
admet-1885	276	10	,	,	PUNCT
admet-1885	276	11	where	where	SCONJ
admet-1885	276	12	the	the	DET
admet-1885	276	13	amide	amide	NOUN
admet-1885	276	14	peak	peak	NOUN
admet-1885	276	15	was	be	AUX
admet-1885	276	16	shortened	shorten	VERB
admet-1885	276	17	,	,	PUNCT
admet-1885	276	18	and	and	CCONJ
admet-1885	276	19	its	its	PRON
admet-1885	276	20	absorption	absorption	NOUN
admet-1885	276	21	was	be	AUX
admet-1885	276	22	weakened	weaken	VERB
admet-1885	276	23	.	.	PUNCT
admet-1885	277	1	figure	figure	NOUN
admet-1885	277	2	8	8	NUM
admet-1885	277	3	.	.	PUNCT
admet-1885	278	1	interaction	interaction	NOUN
admet-1885	278	2	of	of	ADP
admet-1885	278	3	ap	ap	PROPN
admet-1885	278	4	with	with	ADP
admet-1885	278	5	βcd	βcd	VERB
admet-1885	278	6	as	as	SCONJ
admet-1885	278	7	proposed	propose	VERB
admet-1885	278	8	by	by	ADP
admet-1885	278	9	gaussian09	gaussian09	NOUN
admet-1885	278	10	software	software	NOUN
admet-1885	278	11	.	.	PUNCT
admet-1885	279	1	figure	figure	NOUN
admet-1885	279	2	9	9	NUM
admet-1885	279	3	.	.	PUNCT
admet-1885	280	1	interaction	interaction	NOUN
admet-1885	280	2	of	of	ADP
admet-1885	280	3	ap	ap	PROPN
admet-1885	280	4	with	with	ADP
admet-1885	280	5	hpβcd	hpβcd	INTJ
admet-1885	280	6	as	as	SCONJ
admet-1885	280	7	proposed	propose	VERB
admet-1885	280	8	by	by	ADP
admet-1885	280	9	gaussian09	gaussian09	NOUN
admet-1885	280	10	software	software	NOUN
admet-1885	280	11	.	.	PUNCT
admet-1885	281	1	admet	admet	PROPN
admet-1885	281	2	&	&	CCONJ
admet-1885	281	3	dmpk	dmpk	PROPN
admet-1885	281	4	11(4	11(4	NUM
admet-1885	281	5	)	)	PUNCT
admet-1885	281	6	(	(	PUNCT
admet-1885	281	7	2023	2023	NUM
admet-1885	281	8	)	)	PUNCT
admet-1885	281	9	533	533	NUM
admet-1885	281	10	-	-	SYM
admet-1885	281	11	550	550	NUM
admet-1885	281	12	enhancement	enhancement	NOUN
admet-1885	281	13	of	of	ADP
admet-1885	281	14	apixaban	apixaban	ADJ
admet-1885	281	15	solubility	solubility	NOUN
admet-1885	281	16	by	by	ADP
admet-1885	281	17	cyclodextrins	cyclodextrin	NOUN
admet-1885	281	18	doi	doi	PROPN
admet-1885	281	19	:	:	PUNCT
admet-1885	281	20	https://doi.org/10.5599/adme	https://doi.org/10.5599/adme	NOUN
admet-1885	281	21	t.1885	t.1885	ADP
admet-1885	281	22	547	547	NUM
admet-1885	281	23	dissolution	dissolution	NOUN
admet-1885	281	24	studies	study	NOUN
admet-1885	281	25	the	the	DET
admet-1885	281	26	dissolution	dissolution	NOUN
admet-1885	281	27	rate	rate	NOUN
admet-1885	281	28	profiles	profile	NOUN
admet-1885	281	29	of	of	ADP
admet-1885	281	30	standard	standard	NOUN
admet-1885	281	31	ap	ap	PROPN
admet-1885	281	32	alone	alone	ADJ
admet-1885	281	33	and	and	CCONJ
admet-1885	281	34	ap	ap	VERB
admet-1885	281	35	-	-	PUNCT
admet-1885	281	36	hpβcd	hpβcd	ADJ
admet-1885	281	37	(	(	PUNCT
admet-1885	281	38	1:2	1:2	NUM
admet-1885	281	39	)	)	PUNCT
admet-1885	281	40	system	system	NOUN
admet-1885	281	41	in	in	ADP
admet-1885	281	42	ph	ph	PROPN
admet-1885	281	43	6.8	6.8	NUM
admet-1885	281	44	at	at	ADP
admet-1885	281	45	37.0	37.0	NUM
admet-1885	281	46	±	±	NUM
admet-1885	281	47	0.5	0.5	NUM
admet-1885	281	48	°	°	PRON
admet-1885	281	49	c	c	NOUN
admet-1885	281	50	are	be	AUX
admet-1885	281	51	displayed	display	VERB
admet-1885	281	52	in	in	ADP
admet-1885	281	53	figures	figure	NOUN
admet-1885	281	54	10	10	NUM
admet-1885	281	55	and	and	CCONJ
admet-1885	281	56	11	11	NUM
admet-1885	281	57	.	.	PUNCT
admet-1885	282	1	the	the	DET
admet-1885	282	2	release	release	NOUN
admet-1885	282	3	rate	rate	NOUN
admet-1885	282	4	profiles	profile	NOUN
admet-1885	282	5	were	be	AUX
admet-1885	282	6	expressed	express	VERB
admet-1885	282	7	as	as	ADP
admet-1885	282	8	the	the	DET
admet-1885	282	9	amount	amount	NOUN
admet-1885	282	10	(	(	PUNCT
admet-1885	282	11	amount	amount	NOUN
admet-1885	282	12	released×100	released×100	NOUN
admet-1885	282	13	/	/	SYM
admet-1885	282	14	total	total	NOUN
admet-1885	282	15	amount	amount	NOUN
admet-1885	282	16	(	(	PUNCT
admet-1885	282	17	5	5	NUM
admet-1885	282	18	mg	mg	NUM
admet-1885	282	19	)	)	PUNCT
admet-1885	282	20	)	)	PUNCT
admet-1885	282	21	of	of	ADP
admet-1885	282	22	ap	ap	PROPN
admet-1885	282	23	released	release	VERB
admet-1885	282	24	from	from	ADP
admet-1885	282	25	the	the	DET
admet-1885	282	26	complexes	complex	NOUN
admet-1885	282	27	against	against	ADP
admet-1885	282	28	time	time	NOUN
admet-1885	282	29	in	in	ADP
admet-1885	282	30	minutes	minute	NOUN
admet-1885	282	31	.	.	PUNCT
admet-1885	283	1	figure	figure	VERB
admet-1885	283	2	10	10	NUM
admet-1885	283	3	.	.	PUNCT
admet-1885	284	1	dissolution	dissolution	PROPN
admet-1885	284	2	profile	profile	NOUN
admet-1885	284	3	of	of	ADP
admet-1885	284	4	ap	ap	PROPN
admet-1885	284	5	free	free	ADJ
admet-1885	284	6	powder	powder	NOUN
admet-1885	284	7	and	and	CCONJ
admet-1885	284	8	ap	ap	VERB
admet-1885	284	9	-	-	PUNCT
admet-1885	284	10	hpβcd	hpβcd	ADJ
admet-1885	284	11	(	(	PUNCT
admet-1885	284	12	1:2	1:2	NUM
admet-1885	284	13	)	)	PUNCT
admet-1885	284	14	powder	powder	NOUN
admet-1885	284	15	at	at	ADP
admet-1885	284	16	37	37	NUM
admet-1885	284	17	°	°	NOUN
admet-1885	284	18	c	c	NOUN
admet-1885	284	19	,	,	PUNCT
admet-1885	284	20	50	50	NUM
admet-1885	284	21	rpm	rpm	NOUN
admet-1885	284	22	,	,	PUNCT
admet-1885	284	23	usp	usp	PROPN
admet-1885	284	24	dissolution	dissolution	NOUN
admet-1885	284	25	apparatus	apparatus	PROPN
admet-1885	284	26	type	type	PROPN
admet-1885	284	27	ii	ii	PROPN
admet-1885	284	28	.	.	PUNCT
admet-1885	285	1	figure	figure	NOUN
admet-1885	285	2	11	11	NUM
admet-1885	285	3	.	.	PUNCT
admet-1885	286	1	dissolution	dissolution	PROPN
admet-1885	286	2	profile	profile	NOUN
admet-1885	286	3	of	of	ADP
admet-1885	286	4	ap	ap	PROPN
admet-1885	286	5	free	free	PROPN
admet-1885	286	6	ap	ap	PROPN
admet-1885	286	7	-	-	PUNCT
admet-1885	286	8	hpβcd	hpβcd	ADJ
admet-1885	286	9	(	(	PUNCT
admet-1885	286	10	1:2	1:2	NUM
admet-1885	286	11	)	)	PUNCT
admet-1885	286	12	from	from	ADP
admet-1885	286	13	capsule	capsule	ADJ
admet-1885	286	14	dosage	dosage	NOUN
admet-1885	286	15	form	form	NOUN
admet-1885	286	16	37	37	NUM
admet-1885	286	17	°	°	NOUN
admet-1885	286	18	c	c	NOUN
admet-1885	286	19	,	,	PUNCT
admet-1885	286	20	50	50	NUM
admet-1885	286	21	rpm	rpm	NOUN
admet-1885	286	22	,	,	PUNCT
admet-1885	286	23	usp	usp	PROPN
admet-1885	286	24	dissolution	dissolution	NOUN
admet-1885	286	25	apparatus	apparatus	PROPN
admet-1885	286	26	type	type	PROPN
admet-1885	286	27	ii	ii	PROPN
admet-1885	286	28	.	.	PUNCT
admet-1885	286	29	figure	figure	NOUN
admet-1885	286	30	10	10	NUM
admet-1885	286	31	shows	show	VERB
admet-1885	286	32	an	an	DET
admet-1885	286	33	improvement	improvement	NOUN
admet-1885	286	34	in	in	ADP
admet-1885	286	35	the	the	DET
admet-1885	286	36	dissolution	dissolution	NOUN
admet-1885	286	37	rate	rate	NOUN
admet-1885	286	38	of	of	ADP
admet-1885	286	39	ap	ap	PROPN
admet-1885	286	40	released	release	VERB
admet-1885	286	41	from	from	ADP
admet-1885	286	42	ap	ap	PROPN
admet-1885	286	43	-	-	PUNCT
admet-1885	286	44	hpβcd	hpβcd	ADJ
admet-1885	286	45	(	(	PUNCT
admet-1885	286	46	1:2	1:2	NUM
admet-1885	286	47	)	)	PUNCT
admet-1885	286	48	powder	powder	NOUN
admet-1885	286	49	over	over	ADP
admet-1885	286	50	ap	ap	PROPN
admet-1885	286	51	pure	pure	ADJ
admet-1885	286	52	powder	powder	NOUN
admet-1885	286	53	.	.	PUNCT
admet-1885	287	1	this	this	PRON
admet-1885	287	2	indicates	indicate	VERB
admet-1885	287	3	improvement	improvement	NOUN
admet-1885	287	4	of	of	ADP
admet-1885	287	5	solubility	solubility	NOUN
admet-1885	287	6	of	of	ADP
admet-1885	287	7	ap	ap	PROPN
admet-1885	287	8	by	by	ADP
admet-1885	287	9	complexation	complexation	NOUN
admet-1885	287	10	with	with	ADP
admet-1885	287	11	hpβcd	hpβcd	NUM
admet-1885	287	12	.	.	PUNCT
admet-1885	288	1	the	the	DET
admet-1885	288	2	amount	amount	NOUN
admet-1885	288	3	released	release	VERB
admet-1885	288	4	in	in	ADP
admet-1885	288	5	10	10	NUM
admet-1885	288	6	minutes	minute	NOUN
admet-1885	288	7	(	(	PUNCT
admet-1885	288	8	t10	t10	NOUN
admet-1885	288	9	)	)	PUNCT
admet-1885	288	10	was	be	AUX
admet-1885	288	11	taken	take	VERB
admet-1885	288	12	as	as	ADP
admet-1885	288	13	a	a	DET
admet-1885	288	14	comparison	comparison	NOUN
admet-1885	288	15	point	point	NOUN
admet-1885	288	16	and	and	CCONJ
admet-1885	288	17	results	result	NOUN
admet-1885	288	18	showed	show	VERB
admet-1885	288	19	a	a	DET
admet-1885	288	20	significant	significant	ADJ
admet-1885	288	21	increase	increase	NOUN
admet-1885	288	22	in	in	ADP
admet-1885	288	23	ap	ap	PROPN
admet-1885	288	24	dissolved	dissolve	VERB
admet-1885	288	25	from	from	ADP
admet-1885	288	26	hpβcd	hpβcd	ADJ
admet-1885	288	27	complexes	complex	NOUN
admet-1885	288	28	(	(	PUNCT
admet-1885	288	29	52	52	NUM
admet-1885	288	30	±	±	NUM
admet-1885	288	31	3.5	3.5	NUM
admet-1885	288	32	)	)	PUNCT
admet-1885	288	33	5	5	NUM
admet-1885	288	34	compared	compare	VERB
admet-1885	288	35	to	to	AUX
admet-1885	288	36	ap	ap	VERB
admet-1885	288	37	pure	pure	ADJ
admet-1885	288	38	powder	powder	NOUN
admet-1885	288	39	(	(	PUNCT
admet-1885	288	40	30	30	NUM
admet-1885	288	41	±	±	NUM
admet-1885	288	42	4.0	4.0	NUM
admet-1885	288	43	)	)	PUNCT
admet-1885	288	44	with	with	ADP
admet-1885	288	45	(	(	PUNCT
admet-1885	288	46	p<0.05	p<0.05	NOUN
admet-1885	288	47	)	)	PUNCT
admet-1885	288	48	.	.	PUNCT
admet-1885	288	49	https://doi.org/10.5599/admet.1885	https://doi.org/10.5599/admet.1885	PROPN
admet-1885	288	50	z.	z.	PROPN
admet-1885	288	51	n.	n.	PROPN
admet-1885	288	52	salman	salman	PROPN
admet-1885	288	53	et	et	PROPN
admet-1885	288	54	al	al	PROPN
admet-1885	288	55	.	.	PROPN
admet-1885	288	56	admet	admet	PROPN
admet-1885	288	57	&	&	CCONJ
admet-1885	288	58	dmpk	dmpk	PROPN
admet-1885	288	59	11(4	11(4	NUM
admet-1885	288	60	)	)	PUNCT
admet-1885	288	61	(	(	PUNCT
admet-1885	288	62	2023	2023	NUM
admet-1885	288	63	)	)	PUNCT
admet-1885	288	64	533	533	NUM
admet-1885	288	65	-	-	SYM
admet-1885	288	66	550	550	NUM
admet-1885	288	67	548	548	NUM
admet-1885	288	68	ap	ap	NOUN
admet-1885	288	69	release	release	NOUN
admet-1885	288	70	from	from	ADP
admet-1885	288	71	capsule	capsule	ADJ
admet-1885	288	72	dosage	dosage	NOUN
admet-1885	288	73	form	form	NOUN
admet-1885	288	74	(	(	PUNCT
admet-1885	288	75	free	free	PROPN
admet-1885	288	76	ap	ap	PROPN
admet-1885	288	77	versus	versus	ADP
admet-1885	288	78	complex	complex	NOUN
admet-1885	288	79	)	)	PUNCT
admet-1885	288	80	is	be	AUX
admet-1885	288	81	shown	show	VERB
admet-1885	288	82	in	in	ADP
admet-1885	288	83	figure	figure	NOUN
admet-1885	288	84	11	11	NUM
admet-1885	288	85	.	.	PUNCT
admet-1885	289	1	time	time	NOUN
admet-1885	289	2	started	start	VERB
admet-1885	289	3	after	after	SCONJ
admet-1885	289	4	the	the	DET
admet-1885	289	5	capsules	capsule	NOUN
admet-1885	289	6	were	be	AUX
admet-1885	289	7	perforated	perforate	VERB
admet-1885	289	8	in	in	ADP
admet-1885	289	9	the	the	DET
admet-1885	289	10	media	medium	NOUN
admet-1885	289	11	and	and	CCONJ
admet-1885	289	12	the	the	DET
admet-1885	289	13	powder	powder	NOUN
admet-1885	289	14	started	start	VERB
admet-1885	289	15	to	to	PART
admet-1885	289	16	spread	spread	VERB
admet-1885	289	17	in	in	ADP
admet-1885	289	18	the	the	DET
admet-1885	289	19	media	medium	NOUN
admet-1885	289	20	in	in	ADP
admet-1885	289	21	about	about	ADV
admet-1885	289	22	20	20	NUM
admet-1885	289	23	±3	±3	ADJ
admet-1885	289	24	minutes	minute	NOUN
admet-1885	289	25	.	.	PUNCT
admet-1885	290	1	results	result	NOUN
admet-1885	290	2	showed	show	VERB
admet-1885	290	3	the	the	DET
admet-1885	290	4	dissolution	dissolution	NOUN
admet-1885	290	5	was	be	AUX
admet-1885	290	6	significantly	significantly	ADV
admet-1885	290	7	improved	improve	VERB
admet-1885	290	8	compared	compare	VERB
admet-1885	290	9	to	to	ADP
admet-1885	290	10	the	the	DET
admet-1885	290	11	free	free	ADJ
admet-1885	290	12	-ap	-ap	NOUN
admet-1885	290	13	capsules	capsule	NOUN
admet-1885	290	14	.	.	PUNCT
admet-1885	291	1	t10	t10	NOUN
admet-1885	291	2	from	from	ADP
admet-1885	291	3	capsules	capsule	NOUN
admet-1885	291	4	containing	contain	VERB
admet-1885	291	5	the	the	DET
admet-1885	291	6	complex	complex	NOUN
admet-1885	291	7	was	be	AUX
admet-1885	291	8	55±3.4	55±3.4	NUM
admet-1885	291	9	%	%	NOUN
admet-1885	291	10	compared	compare	VERB
admet-1885	291	11	to	to	ADP
admet-1885	291	12	32±1.5	32±1.5	NUM
admet-1885	291	13	%	%	NOUN
admet-1885	291	14	.	.	PUNCT
admet-1885	292	1	these	these	DET
admet-1885	292	2	results	result	NOUN
admet-1885	292	3	are	be	AUX
admet-1885	292	4	close	close	ADJ
admet-1885	292	5	to	to	ADP
admet-1885	292	6	those	those	PRON
admet-1885	292	7	of	of	ADP
admet-1885	292	8	free	free	ADJ
admet-1885	292	9	powder	powder	NOUN
admet-1885	292	10	.	.	PUNCT
admet-1885	293	1	kinetics	kinetic	NOUN
admet-1885	293	2	of	of	ADP
admet-1885	293	3	drug	drug	NOUN
admet-1885	293	4	release	release	NOUN
admet-1885	293	5	the	the	DET
admet-1885	293	6	in	in	X
admet-1885	293	7	vitro	vitro	X
admet-1885	293	8	drug	drug	NOUN
admet-1885	293	9	release	release	NOUN
admet-1885	293	10	mechanism	mechanism	NOUN
admet-1885	293	11	of	of	ADP
admet-1885	293	12	ap	ap	PROPN
admet-1885	293	13	from	from	ADP
admet-1885	293	14	capsules	capsule	NOUN
admet-1885	293	15	in	in	ADP
admet-1885	293	16	buffer	buffer	NOUN
admet-1885	293	17	ph	ph	NOUN
admet-1885	293	18	6.8	6.8	NUM
admet-1885	293	19	at	at	ADP
admet-1885	293	20	37.0±0.5	37.0±0.5	NUM
admet-1885	293	21	°	°	ADP
admet-1885	293	22	c	c	NOUN
admet-1885	293	23	can	can	AUX
admet-1885	293	24	be	be	AUX
admet-1885	293	25	described	describe	VERB
admet-1885	293	26	by	by	ADP
admet-1885	293	27	fitting	fit	VERB
admet-1885	293	28	the	the	DET
admet-1885	293	29	dissolution	dissolution	NOUN
admet-1885	293	30	data	datum	NOUN
admet-1885	293	31	in	in	ADP
admet-1885	293	32	five	five	NUM
admet-1885	293	33	different	different	ADJ
admet-1885	293	34	kinetic	kinetic	NOUN
admet-1885	293	35	models	model	NOUN
admet-1885	293	36	such	such	ADJ
admet-1885	293	37	as	as	ADP
admet-1885	293	38	zero	zero	NUM
admet-1885	293	39	-	-	PUNCT
admet-1885	293	40	order	order	NOUN
admet-1885	293	41	,	,	PUNCT
admet-1885	293	42	first	first	ADJ
admet-1885	293	43	-	-	PUNCT
admet-1885	293	44	order	order	NOUN
admet-1885	293	45	,	,	PUNCT
admet-1885	293	46	peppas	peppa	NOUN
admet-1885	293	47	,	,	PUNCT
admet-1885	293	48	higuchi	higuchi	ADJ
admet-1885	293	49	,	,	PUNCT
admet-1885	293	50	and	and	CCONJ
admet-1885	293	51	hixson	hixson	PROPN
admet-1885	293	52	–	–	PUNCT
admet-1885	293	53	crowell	crowell	NOUN
admet-1885	293	54	(	(	PUNCT
admet-1885	293	55	table	table	NOUN
admet-1885	293	56	8)	8)	NUM
admet-1885	293	57	.	.	PUNCT
admet-1885	294	1	the	the	DET
admet-1885	294	2	linearity	linearity	NOUN
admet-1885	294	3	was	be	AUX
admet-1885	294	4	calculated	calculate	VERB
admet-1885	294	5	to	to	PART
admet-1885	294	6	determine	determine	VERB
admet-1885	294	7	the	the	DET
admet-1885	294	8	best	good	ADJ
admet-1885	294	9	-	-	PUNCT
admet-1885	294	10	fit	fit	ADJ
admet-1885	294	11	model	model	NOUN
admet-1885	294	12	and	and	CCONJ
admet-1885	294	13	possible	possible	ADJ
admet-1885	294	14	mechanism	mechanism	NOUN
admet-1885	294	15	of	of	ADP
admet-1885	294	16	drug	drug	NOUN
admet-1885	294	17	release	release	NOUN
admet-1885	294	18	from	from	ADP
admet-1885	294	19	the	the	DET
admet-1885	294	20	formula	formula	NOUN
admet-1885	294	21	.	.	PUNCT
admet-1885	295	1	drug	drug	NOUN
admet-1885	295	2	release	release	NOUN
admet-1885	295	3	kinetics	kinetic	NOUN
admet-1885	295	4	was	be	AUX
admet-1885	295	5	studied	study	VERB
admet-1885	295	6	for	for	ADP
admet-1885	295	7	the	the	DET
admet-1885	295	8	capsules	capsule	NOUN
admet-1885	295	9	(	(	PUNCT
admet-1885	295	10	reference	reference	NOUN
admet-1885	295	11	and	and	CCONJ
admet-1885	295	12	ap	ap	VERB
admet-1885	295	13	-	-	PUNCT
admet-1885	295	14	hpβcd	hpβcd	ADJ
admet-1885	295	15	(	(	PUNCT
admet-1885	295	16	1:2	1:2	NUM
admet-1885	295	17	)	)	PUNCT
admet-1885	295	18	containing	contain	VERB
admet-1885	295	19	capsules	capsule	NOUN
admet-1885	295	20	)	)	PUNCT
admet-1885	295	21	using	use	VERB
admet-1885	295	22	the	the	DET
admet-1885	295	23	models	model	NOUN
admet-1885	295	24	shown	show	VERB
admet-1885	295	25	in	in	ADP
admet-1885	295	26	table	table	NOUN
admet-1885	295	27	8	8	NUM
admet-1885	295	28	using	use	VERB
admet-1885	295	29	microsoft	microsoft	PROPN
admet-1885	295	30	excel	excel	VERB
admet-1885	295	31	for	for	ADP
admet-1885	295	32	the	the	DET
admet-1885	295	33	model	model	NOUN
admet-1885	295	34	fitting	fitting	ADJ
admet-1885	295	35	and	and	CCONJ
admet-1885	295	36	calculations	calculation	NOUN
admet-1885	295	37	.	.	PUNCT
admet-1885	296	1	the	the	DET
admet-1885	296	2	aim	aim	NOUN
admet-1885	296	3	is	be	AUX
admet-1885	296	4	to	to	PART
admet-1885	296	5	get	get	VERB
admet-1885	296	6	a	a	DET
admet-1885	296	7	straight	straight	ADJ
admet-1885	296	8	line	line	NOUN
admet-1885	296	9	that	that	PRON
admet-1885	296	10	explains	explain	VERB
admet-1885	296	11	the	the	DET
admet-1885	296	12	linear	linear	PROPN
admet-1885	296	13	relation	relation	NOUN
admet-1885	296	14	between	between	ADP
admet-1885	296	15	the	the	DET
admet-1885	296	16	specified	specified	ADJ
admet-1885	296	17	variables	variable	NOUN
admet-1885	296	18	.	.	PUNCT
admet-1885	297	1	linearity	linearity	NOUN
admet-1885	297	2	is	be	AUX
admet-1885	297	3	evaluated	evaluate	VERB
admet-1885	297	4	by	by	ADP
admet-1885	297	5	correlation	correlation	NOUN
admet-1885	297	6	coefficient	coefficient	NOUN
admet-1885	297	7	(	(	PUNCT
admet-1885	297	8	r2	r2	PROPN
admet-1885	297	9	)	)	PUNCT
admet-1885	297	10	to	to	PART
admet-1885	297	11	choose	choose	VERB
admet-1885	297	12	the	the	DET
admet-1885	297	13	best	good	ADJ
admet-1885	297	14	-	-	PUNCT
admet-1885	297	15	fit	fit	ADJ
admet-1885	297	16	model	model	NOUN
admet-1885	297	17	(	(	PUNCT
admet-1885	297	18	table	table	NOUN
admet-1885	297	19	8)	8)	NUM
admet-1885	297	20	.	.	PUNCT
admet-1885	298	1	the	the	DET
admet-1885	298	2	equation	equation	NOUN
admet-1885	298	3	that	that	PRON
admet-1885	298	4	best	good	ADJ
admet-1885	298	5	suits	suit	VERB
admet-1885	298	6	the	the	DET
admet-1885	298	7	dissolution	dissolution	NOUN
admet-1885	298	8	data	datum	NOUN
admet-1885	298	9	where	where	SCONJ
admet-1885	298	10	the	the	DET
admet-1885	298	11	values	value	NOUN
admet-1885	298	12	of	of	ADP
admet-1885	298	13	r2	r2	PROPN
admet-1885	298	14	were	be	AUX
admet-1885	298	15	>	>	X
admet-1885	298	16	0.9	0.9	NUM
admet-1885	298	17	.	.	PUNCT
admet-1885	299	1	results	result	NOUN
admet-1885	299	2	of	of	ADP
admet-1885	299	3	model	model	NOUN
admet-1885	299	4	fitting	fitting	ADJ
admet-1885	299	5	(	(	PUNCT
admet-1885	299	6	table	table	NOUN
admet-1885	299	7	8)	8)	NUM
admet-1885	299	8	showed	show	VERB
admet-1885	299	9	that	that	SCONJ
admet-1885	299	10	ap	ap	PROPN
admet-1885	299	11	is	be	AUX
admet-1885	299	12	released	release	VERB
admet-1885	299	13	from	from	ADP
admet-1885	299	14	the	the	DET
admet-1885	299	15	complex	complex	NOUN
admet-1885	299	16	in	in	ADP
admet-1885	299	17	a	a	DET
admet-1885	299	18	capsule	capsule	NOUN
admet-1885	299	19	dosage	dosage	NOUN
admet-1885	299	20	form	form	NOUN
admet-1885	299	21	following	follow	VERB
admet-1885	299	22	“	"	PUNCT
admet-1885	299	23	first	first	ADJ
admet-1885	299	24	order	order	NOUN
admet-1885	299	25	”	"	PUNCT
admet-1885	299	26	release	release	NOUN
admet-1885	299	27	kinetic	kinetic	NOUN
admet-1885	299	28	with	with	ADP
admet-1885	299	29	a	a	DET
admet-1885	299	30	total	total	ADJ
admet-1885	299	31	amount	amount	NOUN
admet-1885	299	32	released	release	VERB
admet-1885	299	33	in	in	ADP
admet-1885	299	34	1	1	NUM
admet-1885	299	35	hour	hour	NOUN
admet-1885	299	36	of	of	ADP
admet-1885	299	37	more	more	ADJ
admet-1885	299	38	than	than	ADP
admet-1885	299	39	90	90	NUM
admet-1885	299	40	%	%	NOUN
admet-1885	299	41	,	,	PUNCT
admet-1885	299	42	which	which	PRON
admet-1885	299	43	is	be	AUX
admet-1885	299	44	a	a	DET
admet-1885	299	45	suitable	suitable	ADJ
admet-1885	299	46	behavior	behavior	NOUN
admet-1885	299	47	for	for	ADP
admet-1885	299	48	immediate	immediate	ADJ
admet-1885	299	49	release	release	NOUN
admet-1885	299	50	(	(	PUNCT
admet-1885	299	51	ir	ir	NOUN
admet-1885	299	52	)	)	PUNCT
admet-1885	299	53	dosage	dosage	NOUN
admet-1885	299	54	form	form	NOUN
admet-1885	299	55	indicating	indicate	VERB
admet-1885	299	56	first	first	ADJ
admet-1885	299	57	-	-	PUNCT
admet-1885	299	58	order	order	NOUN
admet-1885	299	59	release	release	NOUN
admet-1885	299	60	mechanism	mechanism	NOUN
admet-1885	299	61	.	.	PUNCT
admet-1885	300	1	these	these	DET
admet-1885	300	2	results	result	NOUN
admet-1885	300	3	also	also	ADV
admet-1885	300	4	indicated	indicate	VERB
admet-1885	300	5	that	that	SCONJ
admet-1885	300	6	the	the	DET
admet-1885	300	7	complex	complex	NOUN
admet-1885	300	8	significantly	significantly	ADV
admet-1885	300	9	improved	improve	VERB
admet-1885	300	10	the	the	DET
admet-1885	300	11	drug	drug	NOUN
admet-1885	300	12	release	release	NOUN
admet-1885	300	13	and	and	CCONJ
admet-1885	300	14	dissolution	dissolution	ADJ
admet-1885	300	15	behavior	behavior	NOUN
admet-1885	300	16	.	.	PUNCT
admet-1885	301	1	table	table	NOUN
admet-1885	301	2	8	8	NUM
admet-1885	301	3	.	.	PUNCT
admet-1885	302	1	results	result	NOUN
admet-1885	302	2	of	of	ADP
admet-1885	302	3	model	model	NOUN
admet-1885	302	4	fitting	fit	VERB
admet-1885	302	5	for	for	ADP
admet-1885	302	6	drug	drug	NOUN
admet-1885	302	7	release	release	NOUN
admet-1885	302	8	from	from	ADP
admet-1885	302	9	reference	reference	NOUN
admet-1885	302	10	capsules	capsule	NOUN
admet-1885	302	11	and	and	CCONJ
admet-1885	302	12	capsules	capsule	NOUN
admet-1885	302	13	contain	contain	VERB
admet-1885	302	14	(	(	PUNCT
admet-1885	302	15	ap	ap	VERB
admet-1885	302	16	-	-	PUNCT
admet-1885	302	17	hpβcd	hpβcd	ADJ
admet-1885	302	18	)	)	PUNCT
admet-1885	302	19	.	.	PUNCT
admet-1885	303	1	model	model	NOUN
admet-1885	303	2	zero	zero	NUM
admet-1885	303	3	-	-	PUNCT
admet-1885	303	4	order	order	NOUN
admet-1885	303	5	first	first	ADJ
admet-1885	303	6	order	order	NOUN
admet-1885	303	7	peppas	peppa	NOUN
admet-1885	303	8	model	model	VERB
admet-1885	303	9	higuchi	higuchi	PROPN
admet-1885	303	10	model	model	PROPN
admet-1885	303	11	hixon	hixon	PROPN
admet-1885	303	12	crowel	crowel	PROPN
admet-1885	303	13	model	model	PROPN
admet-1885	303	14	ap	ap	PROPN
admet-1885	304	1	release	release	NOUN
admet-1885	304	2	from	from	ADP
admet-1885	304	3	the	the	DET
admet-1885	304	4	reference	reference	NOUN
admet-1885	304	5	capsule	capsule	NOUN
admet-1885	304	6	r2	r2	PROPN
admet-1885	304	7	0.88	0.88	NUM
admet-1885	304	8	0.94	0.94	NUM
admet-1885	304	9	0.91	0.91	NUM
admet-1885	304	10	0.96	0.96	NUM
admet-1885	304	11	0.94	0.94	NUM
admet-1885	304	12	ap	ap	NOUN
admet-1885	304	13	release	release	NOUN
admet-1885	304	14	from	from	ADP
admet-1885	304	15	capsules	capsule	NOUN
admet-1885	304	16	contains	contain	NOUN
admet-1885	304	17	(	(	PUNCT
admet-1885	304	18	ap	ap	VERB
admet-1885	304	19	-	-	PUNCT
admet-1885	304	20	hpβcd	hpβcd	ADJ
admet-1885	304	21	)	)	PUNCT
admet-1885	304	22	r2	r2	PROPN
admet-1885	304	23	0.80	0.80	NUM
admet-1885	304	24	0.99	0.99	NUM
admet-1885	304	25	0.98	0.98	NUM
admet-1885	304	26	0.97	0.97	NUM
admet-1885	304	27	0.95	0.95	NUM
admet-1885	304	28	conclusions	conclusion	NOUN
admet-1885	304	29	ap	ap	PROPN
admet-1885	304	30	forms	form	VERB
admet-1885	304	31	a	a	DET
admet-1885	304	32	complex	complex	NOUN
admet-1885	304	33	with	with	ADP
admet-1885	304	34	βcd	βcd	NOUN
admet-1885	304	35	and	and	CCONJ
admet-1885	304	36	hpβcd	hpβcd	ADJ
admet-1885	304	37	with	with	ADP
admet-1885	304	38	good	good	ADJ
admet-1885	304	39	loading	loading	NOUN
admet-1885	304	40	efficiency	efficiency	NOUN
admet-1885	304	41	using	use	VERB
admet-1885	304	42	the	the	DET
admet-1885	304	43	kneading	kneading	NOUN
admet-1885	304	44	method	method	NOUN
admet-1885	304	45	,	,	PUNCT
admet-1885	304	46	solvent	solvent	ADJ
admet-1885	304	47	evaporation	evaporation	NOUN
admet-1885	304	48	method	method	NOUN
admet-1885	304	49	and	and	CCONJ
admet-1885	304	50	spray	spray	VERB
admet-1885	304	51	drying	dry	VERB
admet-1885	304	52	method	method	NOUN
admet-1885	304	53	.	.	PUNCT
admet-1885	305	1	the	the	DET
admet-1885	305	2	highest	high	ADJ
admet-1885	305	3	percentage	percentage	NOUN
admet-1885	305	4	was	be	AUX
admet-1885	305	5	gained	gain	VERB
admet-1885	305	6	from	from	ADP
admet-1885	305	7	the	the	DET
admet-1885	305	8	kneading	kneading	NOUN
admet-1885	305	9	method	method	NOUN
admet-1885	305	10	in	in	ADP
admet-1885	305	11	a	a	DET
admet-1885	305	12	ratio	ratio	NOUN
admet-1885	305	13	of	of	ADP
admet-1885	305	14	1:2	1:2	NUM
admet-1885	305	15	ap	ap	PROPN
admet-1885	305	16	-	-	PUNCT
admet-1885	305	17	hpβcd	hpβcd	PROPN
admet-1885	305	18	.	.	PUNCT
admet-1885	306	1	also	also	ADV
admet-1885	306	2	,	,	PUNCT
admet-1885	306	3	the	the	DET
admet-1885	306	4	phase	phase	NOUN
admet-1885	306	5	solubility	solubility	NOUN
admet-1885	306	6	study	study	NOUN
admet-1885	306	7	showed	show	VERB
admet-1885	306	8	that	that	SCONJ
admet-1885	306	9	ap	ap	PROPN
admet-1885	306	10	reacts	react	VERB
admet-1885	306	11	with	with	ADP
admet-1885	306	12	hpβcd	hpβcd	NUM
admet-1885	306	13	in	in	ADP
admet-1885	306	14	a	a	DET
admet-1885	306	15	ratio	ratio	NOUN
admet-1885	306	16	of	of	ADP
admet-1885	306	17	1:1	1:1	NUM
admet-1885	306	18	stoichiometry	stoichiometry	NOUN
admet-1885	306	19	with	with	ADP
admet-1885	306	20	a	a	DET
admet-1885	306	21	stability	stability	NOUN
admet-1885	306	22	constant	constant	ADJ
admet-1885	306	23	equal	equal	ADJ
admet-1885	306	24	to	to	ADP
admet-1885	306	25	994	994	NUM
admet-1885	306	26	m-1	m-1	NUM
admet-1885	306	27	..	..	PUNCT
admet-1885	306	28	computer	computer	NOUN
admet-1885	306	29	simulation	simulation	NOUN
admet-1885	306	30	of	of	ADP
admet-1885	306	31	the	the	DET
admet-1885	306	32	ap	ap	PROPN
admet-1885	306	33	-	-	PUNCT
admet-1885	306	34	cd	cd	PROPN
admet-1885	306	35	interaction	interaction	NOUN
admet-1885	306	36	supports	support	VERB
admet-1885	306	37	the	the	DET
admet-1885	306	38	formation	formation	NOUN
admet-1885	306	39	of	of	ADP
admet-1885	306	40	1:1	1:1	NUM
admet-1885	306	41	complex	complex	NOUN
admet-1885	306	42	.	.	PUNCT
admet-1885	307	1	for	for	ADP
admet-1885	307	2	characterization	characterization	NOUN
admet-1885	307	3	purposes	purpose	NOUN
admet-1885	307	4	,	,	PUNCT
admet-1885	307	5	ftir	ftir	PROPN
admet-1885	307	6	and	and	CCONJ
admet-1885	307	7	dsc	dsc	PROPN
admet-1885	307	8	showed	show	VERB
admet-1885	307	9	a	a	DET
admet-1885	307	10	physical	physical	ADJ
admet-1885	307	11	interaction	interaction	NOUN
admet-1885	307	12	between	between	ADP
admet-1885	307	13	ap	ap	PROPN
admet-1885	307	14	and	and	CCONJ
admet-1885	307	15	hpβcd	hpβcd	X
admet-1885	307	16	.	.	PUNCT
admet-1885	308	1	additionally	additionally	ADV
admet-1885	308	2	,	,	PUNCT
admet-1885	308	3	drug	drug	NOUN
admet-1885	308	4	dissolution	dissolution	NOUN
admet-1885	308	5	was	be	AUX
admet-1885	308	6	significantly	significantly	ADV
admet-1885	308	7	higher	high	ADJ
admet-1885	308	8	from	from	ADP
admet-1885	308	9	the	the	DET
admet-1885	308	10	powder	powder	NOUN
admet-1885	308	11	of	of	ADP
admet-1885	308	12	the	the	DET
admet-1885	308	13	complex	complex	NOUN
admet-1885	308	14	and	and	CCONJ
admet-1885	308	15	the	the	DET
admet-1885	308	16	formula	formula	NOUN
admet-1885	308	17	of	of	ADP
admet-1885	308	18	gelatin	gelatin	NOUN
admet-1885	308	19	capsules	capsule	NOUN
admet-1885	308	20	compared	compare	VERB
admet-1885	308	21	to	to	ADP
admet-1885	308	22	free	free	VERB
admet-1885	308	23	ap	ap	PROPN
admet-1885	308	24	and	and	CCONJ
admet-1885	308	25	ap	ap	VERB
admet-1885	308	26	in	in	ADP
admet-1885	308	27	capsules	capsule	NOUN
admet-1885	308	28	without	without	ADP
admet-1885	308	29	the	the	DET
admet-1885	308	30	complex	complex	ADJ
admet-1885	308	31	.	.	PUNCT
admet-1885	309	1	list	list	NOUN
admet-1885	309	2	of	of	ADP
admet-1885	309	3	abbreviations	abbreviation	NOUN
admet-1885	309	4	ap	ap	PROPN
admet-1885	310	1	apixaban	apixaban	PROPN
admet-1885	310	2	uv	uv	PROPN
admet-1885	310	3	ultraviolet	ultraviolet	NOUN
admet-1885	310	4	spectrophotometry	spectrophotometry	NOUN
admet-1885	310	5	βcd	βcd	VERB
admet-1885	310	6	beta	beta	ADJ
admet-1885	310	7	cyclodextrin	cyclodextrin	NOUN
admet-1885	310	8	and	and	CCONJ
admet-1885	310	9	hpβcd	hpβcd	ADJ
admet-1885	310	10	hydroxy	hydroxy	NOUN
admet-1885	310	11	propyl	propyl	NOUN
admet-1885	310	12	beta	beta	ADJ
admet-1885	310	13	cyclodextrin	cyclodextrin	NOUN
admet-1885	310	14	ftir	ftir	PROPN
admet-1885	310	15	fourier	fourier	NOUN
admet-1885	310	16	transfer	transfer	NOUN
admet-1885	310	17	infra	infra	NOUN
admet-1885	310	18	-	-	PUNCT
admet-1885	310	19	red	red	ADJ
admet-1885	310	20	dsc	dsc	NOUN
admet-1885	310	21	differential	differential	NOUN
admet-1885	310	22	scanning	scan	VERB
admet-1885	310	23	calorimetry	calorimetry	NOUN
admet-1885	310	24	bcs	bcs	NOUN
admet-1885	310	25	biopharmaceutical	biopharmaceutical	NOUN
admet-1885	310	26	classification	classification	NOUN
admet-1885	310	27	system	system	NOUN
admet-1885	310	28	vte	vte	VERB
admet-1885	310	29	venous	venous	ADJ
admet-1885	310	30	thromboembolism	thromboembolism	NOUN
admet-1885	310	31	sd	sd	ADP
admet-1885	310	32	standard	standard	ADJ
admet-1885	310	33	deviations	deviation	NOUN
admet-1885	310	34	cv	cv	PROPN
admet-1885	310	35	coefficient	coefficient	NOUN
admet-1885	310	36	of	of	ADP
admet-1885	310	37	variation	variation	NOUN
admet-1885	310	38	r2	r2	NOUN
admet-1885	310	39	correlation	correlation	NOUN
admet-1885	310	40	coefficient	coefficient	PROPN
admet-1885	310	41	admet	admet	PROPN
admet-1885	310	42	&	&	CCONJ
admet-1885	310	43	dmpk	dmpk	PROPN
admet-1885	310	44	11(4	11(4	NUM
admet-1885	310	45	)	)	PUNCT
admet-1885	310	46	(	(	PUNCT
admet-1885	310	47	2023	2023	NUM
admet-1885	310	48	)	)	PUNCT
admet-1885	310	49	533	533	NUM
admet-1885	310	50	-	-	SYM
admet-1885	310	51	550	550	NUM
admet-1885	310	52	enhancement	enhancement	NOUN
admet-1885	310	53	of	of	ADP
admet-1885	310	54	apixaban	apixaban	ADJ
admet-1885	310	55	solubility	solubility	NOUN
admet-1885	310	56	by	by	ADP
admet-1885	310	57	cyclodextrins	cyclodextrin	NOUN
admet-1885	310	58	doi	doi	PROPN
admet-1885	310	59	:	:	PUNCT
admet-1885	310	60	https://doi.org/10.5599/adme	https://doi.org/10.5599/adme	NOUN
admet-1885	310	61	t.1885	t.1885	NOUN
admet-1885	310	62	549	549	NUM
admet-1885	310	63	ethics	ethic	NOUN
admet-1885	310	64	approval	approval	NOUN
admet-1885	310	65	and	and	CCONJ
admet-1885	310	66	consent	consent	NOUN
admet-1885	310	67	to	to	PART
admet-1885	310	68	participate	participate	VERB
admet-1885	310	69	:	:	PUNCT
admet-1885	310	70	no	no	DET
admet-1885	310	71	animal	animal	NOUN
admet-1885	310	72	experiments	experiment	NOUN
admet-1885	310	73	have	have	AUX
admet-1885	310	74	been	be	AUX
admet-1885	310	75	conducted	conduct	VERB
admet-1885	310	76	in	in	ADP
admet-1885	310	77	this	this	DET
admet-1885	310	78	study	study	NOUN
admet-1885	310	79	.	.	PUNCT
admet-1885	311	1	human	human	ADJ
admet-1885	311	2	and	and	CCONJ
admet-1885	311	3	animal	animal	NOUN
admet-1885	311	4	rights	right	NOUN
admet-1885	311	5	:	:	PUNCT
admet-1885	311	6	no	no	DET
admet-1885	311	7	humans	human	NOUN
admet-1885	311	8	or	or	CCONJ
admet-1885	311	9	animals	animal	NOUN
admet-1885	311	10	were	be	AUX
admet-1885	311	11	used	use	VERB
admet-1885	311	12	in	in	ADP
admet-1885	311	13	this	this	DET
admet-1885	311	14	study	study	NOUN
admet-1885	311	15	.	.	PUNCT
admet-1885	312	1	availability	availability	NOUN
admet-1885	312	2	of	of	ADP
admet-1885	312	3	data	datum	NOUN
admet-1885	312	4	and	and	CCONJ
admet-1885	312	5	materials	material	NOUN
admet-1885	312	6	:	:	PUNCT
admet-1885	312	7	the	the	DET
admet-1885	312	8	data	datum	NOUN
admet-1885	312	9	used	use	VERB
admet-1885	312	10	to	to	PART
admet-1885	312	11	support	support	VERB
admet-1885	312	12	the	the	DET
admet-1885	312	13	findings	finding	NOUN
admet-1885	312	14	of	of	ADP
admet-1885	312	15	this	this	DET
admet-1885	312	16	study	study	NOUN
admet-1885	312	17	are	be	AUX
admet-1885	312	18	available	available	ADJ
admet-1885	312	19	from	from	ADP
admet-1885	312	20	the	the	DET
admet-1885	312	21	corresponding	correspond	VERB
admet-1885	312	22	authors	author	NOUN
admet-1885	312	23	upon	upon	SCONJ
admet-1885	312	24	request	request	NOUN
admet-1885	312	25	.	.	PUNCT
admet-1885	313	1	conflict	conflict	NOUN
admet-1885	313	2	of	of	ADP
admet-1885	313	3	interest	interest	NOUN
admet-1885	313	4	:	:	PUNCT
admet-1885	313	5	the	the	DET
admet-1885	313	6	authors	author	NOUN
admet-1885	313	7	declare	declare	VERB
admet-1885	313	8	no	no	DET
admet-1885	313	9	conflict	conflict	NOUN
admet-1885	313	10	of	of	ADP
admet-1885	313	11	interest	interest	NOUN
admet-1885	313	12	,	,	PUNCT
admet-1885	313	13	financial	financial	ADJ
admet-1885	313	14	or	or	CCONJ
admet-1885	313	15	otherwise	otherwise	ADV
admet-1885	313	16	.	.	PUNCT
admet-1885	314	1	acknowledgements	acknowledgement	NOUN
admet-1885	314	2	:	:	PUNCT
admet-1885	314	3	the	the	DET
admet-1885	314	4	author	author	NOUN
admet-1885	314	5	gratefully	gratefully	ADV
admet-1885	314	6	thank	thank	VERB
admet-1885	314	7	to	to	ADP
admet-1885	314	8	ysrafil	ysrafil	NOUN
admet-1885	314	9	,	,	PUNCT
admet-1885	314	10	to	to	ADP
admet-1885	314	11	conductiing	conductie	VERB
admet-1885	314	12	this	this	DET
admet-1885	314	13	projects	project	NOUN
admet-1885	314	14	,	,	PUNCT
admet-1885	314	15	apt	apt	ADJ
admet-1885	314	16	.	.	PROPN
admet-1885	314	17	firzan	firzan	PROPN
admet-1885	314	18	nainu	nainu	PROPN
admet-1885	314	19	,	,	PUNCT
admet-1885	314	20	m.	m.	NOUN
admet-1885	314	21	biomed	biome	VERB
admet-1885	314	22	.	.	PUNCT
admet-1885	314	23	,	,	PUNCT
admet-1885	314	24	sc	sc	PROPN
admet-1885	314	25	.	.	PROPN
admet-1885	314	26	,	,	PUNCT
admet-1885	314	27	ph.d	ph.d	PROPN
admet-1885	314	28	and	and	CCONJ
admet-1885	314	29	talha	talha	PROPN
admet-1885	314	30	bin	bin	PROPN
admet-1885	314	31	emran	emran	PROPN
admet-1885	314	32	,	,	PUNCT
admet-1885	314	33	ph.d	ph.d	PROPN
admet-1885	314	34	for	for	ADP
admet-1885	314	35	supervised	supervised	ADJ
admet-1885	314	36	and	and	CCONJ
admet-1885	314	37	grammar	grammar	NOUN
admet-1885	314	38	/	/	SYM
admet-1885	314	39	structural	structural	ADJ
admet-1885	314	40	editing	editing	NOUN
admet-1885	314	41	of	of	ADP
admet-1885	314	42	this	this	DET
admet-1885	314	43	manuscript	manuscript	NOUN
admet-1885	314	44	.	.	PUNCT
admet-1885	315	1	references	reference	NOUN
admet-1885	315	2	[	[	X
admet-1885	315	3	1	1	NUM
admet-1885	315	4	]	]	PUNCT
admet-1885	315	5	a.	a.	NOUN
admet-1885	315	6	sharma	sharma	PROPN
admet-1885	315	7	,	,	PUNCT
admet-1885	315	8	m.	m.	NOUN
admet-1885	315	9	soni	soni	PROPN
admet-1885	315	10	,	,	PUNCT
admet-1885	315	11	s.	s.	PROPN
admet-1885	315	12	kumar	kumar	PROPN
admet-1885	315	13	,	,	PUNCT
admet-1885	315	14	g.d	g.d	PROPN
admet-1885	315	15	.	.	PROPN
admet-1885	315	16	gupta	gupta	PROPN
admet-1885	315	17	.	.	PUNCT
admet-1885	316	1	solubility	solubility	NOUN
admet-1885	316	2	enhancement	enhancement	NOUN
admet-1885	316	3	—	—	PUNCT
admet-1885	316	4	eminent	eminent	ADJ
admet-1885	316	5	role	role	NOUN
admet-1885	316	6	in	in	ADP
admet-1885	316	7	poorly	poorly	ADV
admet-1885	316	8	soluble	soluble	ADJ
admet-1885	316	9	drugs	drug	NOUN
admet-1885	316	10	.	.	PUNCT
admet-1885	317	1	research	research	NOUN
admet-1885	317	2	journal	journal	PROPN
admet-1885	317	3	of	of	ADP
admet-1885	317	4	pharmacy	pharmacy	NOUN
admet-1885	317	5	and	and	CCONJ
admet-1885	317	6	technology	technology	NOUN
admet-1885	317	7	2	2	NUM
admet-1885	317	8	(	(	PUNCT
admet-1885	317	9	2009	2009	NUM
admet-1885	317	10	)	)	PUNCT
admet-1885	317	11	220	220	NUM
admet-1885	317	12	-	-	SYM
admet-1885	317	13	224	224	NUM
admet-1885	317	14	.	.	PUNCT
admet-1885	318	1	https://rjptonline.org/	https://rjptonline.org/	PRON
admet-1885	318	2	abstractview.aspx?pid=2009-2-2-46	abstractview.aspx?pid=2009-2-2-46	PROPN
admet-1885	318	3	[	[	X
admet-1885	318	4	2	2	X
admet-1885	318	5	]	]	PUNCT
admet-1885	318	6	j.	j.	PROPN
admet-1885	318	7	hodgson	hodgson	PROPN
admet-1885	318	8	.	.	PUNCT
admet-1885	319	1	admet	admet	PROPN
admet-1885	319	2	—	—	PUNCT
admet-1885	319	3	turning	turn	VERB
admet-1885	319	4	chemicals	chemical	NOUN
admet-1885	319	5	into	into	ADP
admet-1885	319	6	drugs	drug	NOUN
admet-1885	319	7	.	.	PUNCT
admet-1885	320	1	nature	nature	NOUN
admet-1885	320	2	biotechnology	biotechnology	NOUN
admet-1885	320	3	19	19	NUM
admet-1885	320	4	(	(	PUNCT
admet-1885	320	5	2001	2001	NUM
admet-1885	320	6	)	)	PUNCT
admet-1885	320	7	722	722	NUM
admet-1885	320	8	-	-	SYM
admet-1885	320	9	726	726	NUM
admet-1885	320	10	.	.	PUNCT
admet-1885	321	1	https://	https://	PROPN
admet-1885	321	2	doi.org/10.1038/90761	doi.org/10.1038/90761	PROPN
admet-1885	322	1	[	[	X
admet-1885	322	2	3	3	X
admet-1885	322	3	]	]	X
admet-1885	322	4	k.t	k.t	PROPN
admet-1885	322	5	.	.	PROPN
admet-1885	322	6	savjani	savjani	PROPN
admet-1885	322	7	,	,	PUNCT
admet-1885	322	8	a.k	a.k	PROPN
admet-1885	322	9	.	.	PROPN
admet-1885	322	10	gajjar	gajjar	PROPN
admet-1885	322	11	,	,	PUNCT
admet-1885	322	12	j.k	j.k	PROPN
admet-1885	322	13	.	.	PROPN
admet-1885	322	14	savjani	savjani	PROPN
admet-1885	322	15	.	.	PUNCT
admet-1885	323	1	drug	drug	NOUN
admet-1885	323	2	solubility	solubility	NOUN
admet-1885	323	3	:	:	PUNCT
admet-1885	323	4	importance	importance	NOUN
admet-1885	323	5	and	and	CCONJ
admet-1885	323	6	enhancement	enhancement	NOUN
admet-1885	323	7	techniques	technique	NOUN
admet-1885	323	8	.	.	PUNCT
admet-1885	324	1	international	international	ADJ
admet-1885	324	2	scholary	scholary	ADJ
admet-1885	324	3	research	research	NOUN
admet-1885	324	4	notices	notice	VERB
admet-1885	324	5	2012	2012	NUM
admet-1885	324	6	(	(	PUNCT
admet-1885	324	7	2012	2012	NUM
admet-1885	324	8	)	)	PUNCT
admet-1885	324	9	1–10	1–10	NOUN
admet-1885	324	10	.	.	PUNCT
admet-1885	325	1	https://doi.org/10.5402/2012/195727	https://doi.org/10.5402/2012/195727	PROPN
admet-1885	326	1	[	[	X
admet-1885	326	2	4	4	NUM
admet-1885	326	3	]	]	X
admet-1885	326	4	c.	c.	PROPN
admet-1885	326	5	lipiniski	lipiniski	PROPN
admet-1885	326	6	,	,	PUNCT
admet-1885	326	7	c.j	c.j	PROPN
admet-1885	326	8	lipinski	lipinski	PROPN
admet-1885	326	9	,	,	PUNCT
admet-1885	326	10	c.	c.	PROPN
admet-1885	326	11	lipinski	lipinski	PROPN
admet-1885	326	12	,	,	PUNCT
admet-1885	326	13	c.a	c.a	PROPN
admet-1885	326	14	.	.	PROPN
admet-1885	326	15	lipinski	lipinski	PROPN
admet-1885	326	16	,	,	PUNCT
admet-1885	326	17	c.	c.	PROPN
admet-1885	326	18	lipinski	lipinski	PROPN
admet-1885	326	19	,	,	PUNCT
admet-1885	326	20	c.a	c.a	PROPN
admet-1885	326	21	.	.	PROPN
admet-1885	326	22	lipinski	lipinski	PROPN
admet-1885	326	23	,	,	PUNCT
admet-1885	326	24	lipinski	lipinski	PROPN
admet-1885	326	25	,	,	PUNCT
admet-1885	326	26	c.a	c.a	PROPN
admet-1885	326	27	.	.	PROPN
admet-1885	326	28	lipinski	lipinski	PROPN
admet-1885	326	29	.	.	PUNCT
admet-1885	327	1	poor	poor	ADJ
admet-1885	327	2	aqueous	aqueous	ADJ
admet-1885	327	3	solubility	solubility	NOUN
admet-1885	327	4	an	an	DET
admet-1885	327	5	industry	industry	NOUN
admet-1885	327	6	wide	wide	ADJ
admet-1885	327	7	problem	problem	NOUN
admet-1885	327	8	in	in	ADP
admet-1885	327	9	drug	drug	NOUN
admet-1885	327	10	delivery	delivery	NOUN
admet-1885	327	11	.	.	PUNCT
admet-1885	328	1	american	american	ADJ
admet-1885	328	2	pharmaceutical	pharmaceutical	PROPN
admet-1885	328	3	review	review	PROPN
admet-1885	328	4	5	5	NUM
admet-1885	328	5	(	(	PUNCT
admet-1885	328	6	2002	2002	NUM
admet-1885	328	7	)	)	PUNCT
admet-1885	328	8	82	82	NUM
admet-1885	328	9	-	-	SYM
admet-1885	328	10	85	85	NUM
admet-1885	328	11	.	.	PUNCT
admet-1885	328	12	https://www.scienceopen.com/document?vid=dbc999fb-0f66-463c-8166-d6576f8778d5	https://www.scienceopen.com/document?vid=dbc999fb-0f66-463c-8166-d6576f8778d5	X
admet-1885	329	1	[	[	X
admet-1885	329	2	5	5	NUM
admet-1885	329	3	]	]	PUNCT
admet-1885	329	4	z.	z.	PROPN
admet-1885	329	5	guo	guo	PROPN
admet-1885	329	6	,	,	PUNCT
admet-1885	329	7	c.	c.	PROPN
admet-1885	329	8	boyce	boyce	PROPN
admet-1885	329	9	,	,	PUNCT
admet-1885	329	10	t.	t.	PROPN
admet-1885	329	11	rhodes	rhodes	PROPN
admet-1885	329	12	,	,	PUNCT
admet-1885	329	13	l.	l.	PROPN
admet-1885	329	14	liu	liu	PROPN
admet-1885	329	15	,	,	PUNCT
admet-1885	329	16	g.m	g.m	PROPN
admet-1885	329	17	.	.	PROPN
admet-1885	329	18	salituro	salituro	PROPN
admet-1885	329	19	,	,	PUNCT
admet-1885	329	20	k.j	k.j	PROPN
admet-1885	329	21	.	.	PROPN
admet-1885	329	22	lee	lee	PROPN
admet-1885	329	23	,	,	PUNCT
admet-1885	329	24	a.	a.	PROPN
admet-1885	329	25	bak	bak	PROPN
admet-1885	329	26	,	,	PUNCT
admet-1885	329	27	d.h	d.h	PROPN
admet-1885	329	28	.	.	PROPN
admet-1885	329	29	leung	leung	PROPN
admet-1885	329	30	.	.	PUNCT
admet-1885	330	1	a	a	DET
admet-1885	330	2	novel	novel	ADJ
admet-1885	330	3	method	method	NOUN
admet-1885	330	4	for	for	ADP
admet-1885	330	5	preparing	prepare	VERB
admet-1885	330	6	stabilized	stabilize	VERB
admet-1885	330	7	amorphous	amorphous	ADJ
admet-1885	330	8	solid	solid	ADJ
admet-1885	330	9	dispersion	dispersion	NOUN
admet-1885	330	10	drug	drug	NOUN
admet-1885	330	11	formulations	formulation	NOUN
admet-1885	330	12	using	use	VERB
admet-1885	330	13	acoustic	acoustic	ADJ
admet-1885	330	14	fusion	fusion	NOUN
admet-1885	330	15	.	.	PUNCT
admet-1885	331	1	international	international	ADJ
admet-1885	331	2	journal	journal	PROPN
admet-1885	331	3	of	of	ADP
admet-1885	331	4	pharmaceutics	pharmaceutic	NOUN
admet-1885	331	5	592	592	NUM
admet-1885	331	6	(	(	PUNCT
admet-1885	331	7	2021	2021	NUM
admet-1885	331	8	)	)	PUNCT
admet-1885	331	9	120026	120026	NUM
admet-1885	331	10	.	.	PUNCT
admet-1885	332	1	https://doi.org/10.1016/j.ijpharm.20	https://doi.org/10.1016/j.ijpharm.20	PRON
admet-1885	332	2	20.120026	20.120026	NUM
admet-1885	333	1	[	[	X
admet-1885	333	2	6	6	NUM
admet-1885	333	3	]	]	SYM
admet-1885	333	4	v.r	v.r	PROPN
admet-1885	333	5	.	.	PROPN
admet-1885	333	6	vemula	vemula	PROPN
admet-1885	333	7	,	,	PUNCT
admet-1885	333	8	v.	v.	PROPN
admet-1885	333	9	lagishetty	lagishetty	PROPN
admet-1885	333	10	,	,	PUNCT
admet-1885	333	11	s.	s.	PROPN
admet-1885	333	12	lingala	lingala	PROPN
admet-1885	333	13	.	.	PUNCT
admet-1885	334	1	solubility	solubility	NOUN
admet-1885	334	2	enhancement	enhancement	NOUN
admet-1885	334	3	techniques	technique	NOUN
admet-1885	334	4	.	.	PUNCT
admet-1885	335	1	international	international	ADJ
admet-1885	335	2	journal	journal	PROPN
admet-1885	335	3	of	of	ADP
admet-1885	335	4	pharmaceutical	pharmaceutical	PROPN
admet-1885	335	5	sciences	sciences	PROPN
admet-1885	335	6	review	review	NOUN
admet-1885	335	7	and	and	CCONJ
admet-1885	335	8	research	research	NOUN
admet-1885	335	9	5	5	NUM
admet-1885	335	10	(	(	PUNCT
admet-1885	335	11	2010	2010	NUM
admet-1885	335	12	)	)	PUNCT
admet-1885	335	13	41	41	NUM
admet-1885	335	14	-	-	SYM
admet-1885	335	15	51	51	NUM
admet-1885	335	16	.	.	PUNCT
admet-1885	336	1	https://globalresearchonline.net/jour	https://globalresearchonline.net/jour	PROPN
admet-1885	336	2	nalcontents	nalcontent	NOUN
admet-1885	336	3	/	/	PUNCT
admet-1885	336	4	volume5issue1	volume5issue1	NUM
admet-1885	336	5	/	/	SYM
admet-1885	336	6	article-007.pdf	article-007.pdf	NOUN
admet-1885	336	7	[	[	X
admet-1885	336	8	7	7	NUM
admet-1885	336	9	]	]	X
admet-1885	336	10	d.j	d.j	PROPN
admet-1885	336	11	.	.	PROPN
admet-1885	336	12	pinto	pinto	PROPN
admet-1885	336	13	,	,	PUNCT
admet-1885	336	14	m.j	m.j	PROPN
admet-1885	336	15	.	.	PROPN
admet-1885	336	16	orwat	orwat	PROPN
admet-1885	336	17	,	,	PUNCT
admet-1885	336	18	s.	s.	PROPN
admet-1885	336	19	koch	koch	PROPN
admet-1885	336	20	,	,	PUNCT
admet-1885	336	21	k.a	k.a	PROPN
admet-1885	336	22	.	.	PROPN
admet-1885	336	23	rossi	rossi	PROPN
admet-1885	336	24	,	,	PUNCT
admet-1885	336	25	r.s	r.s	PROPN
admet-1885	336	26	.	.	PROPN
admet-1885	336	27	alexander	alexander	PROPN
admet-1885	336	28	,	,	PUNCT
admet-1885	336	29	a.	a.	PROPN
admet-1885	336	30	smallwood	smallwood	PROPN
admet-1885	336	31	,	,	PUNCT
admet-1885	336	32	p.c	p.c	PROPN
admet-1885	336	33	.	.	PROPN
admet-1885	336	34	wong	wong	PROPN
admet-1885	336	35	,	,	PUNCT
admet-1885	336	36	a.r	a.r	PROPN
admet-1885	336	37	.	.	PROPN
admet-1885	336	38	rendina	rendina	PROPN
admet-1885	336	39	,	,	PUNCT
admet-1885	336	40	j.m	j.m	PROPN
admet-1885	336	41	.	.	PROPN
admet-1885	336	42	luettgen	luettgen	PROPN
admet-1885	336	43	,	,	PUNCT
admet-1885	336	44	r.m	r.m	PROPN
admet-1885	336	45	.	.	PROPN
admet-1885	336	46	knabb	knabb	PROPN
admet-1885	336	47	,	,	PUNCT
admet-1885	336	48	k.	k.	PROPN
admet-1885	337	1	he	he	PRON
admet-1885	337	2	,	,	PUNCT
admet-1885	337	3	b.	b.	PROPN
admet-1885	337	4	xin	xin	PROPN
admet-1885	337	5	,	,	PUNCT
admet-1885	337	6	r.r	r.r	PROPN
admet-1885	337	7	.	.	PROPN
admet-1885	337	8	wexler	wexler	PROPN
admet-1885	337	9	,	,	PUNCT
admet-1885	337	10	p.y.s	p.y.s	PROPN
admet-1885	337	11	.	.	PUNCT
admet-1885	338	1	lam	lam	PROPN
admet-1885	338	2	.	.	PUNCT
admet-1885	339	1	discovery	discovery	PROPN
admet-1885	339	2	of	of	ADP
admet-1885	339	3	1-(4	1-(4	PROPN
admet-1885	339	4	-	-	PUNCT
admet-1885	339	5	methoxyphenyl)-7	methoxyphenyl)-7	NOUN
admet-1885	339	6	-	-	PUNCT
admet-1885	339	7	oxo-6-(4-(2	oxo-6-(4-(2	NOUN
admet-1885	339	8	-	-	PUNCT
admet-1885	339	9	oxopiperidin-1	oxopiperidin-1	NUM
admet-1885	339	10	-	-	PUNCT
admet-1885	339	11	yl	yl	NOUN
admet-1885	339	12	)	)	PUNCT
admet-1885	339	13	phenyl)-4	phenyl)-4	PROPN
admet-1885	339	14	,	,	PUNCT
admet-1885	339	15	5	5	NUM
admet-1885	339	16	,	,	PUNCT
admet-1885	339	17	6	6	NUM
admet-1885	339	18	,	,	PUNCT
admet-1885	339	19	7	7	NUM
admet-1885	339	20	-	-	SYM
admet-1885	339	21	tetrahydro-1	tetrahydro-1	NUM
admet-1885	339	22	h	h	NOUN
admet-1885	339	23	-	-	PUNCT
admet-1885	339	24	pyrazolo	pyrazolo	NOUN
admet-1885	340	1	[	[	X
admet-1885	340	2	3	3	NUM
admet-1885	340	3	,	,	PUNCT
admet-1885	340	4	4	4	NUM
admet-1885	340	5	-	-	SYM
admet-1885	340	6	c	c	NOUN
admet-1885	340	7	]	]	PUNCT
admet-1885	340	8	pyridine3	pyridine3	NOUN
admet-1885	340	9	-	-	PUNCT
admet-1885	340	10	carboxamide	carboxamide	NOUN
admet-1885	340	11	(	(	PUNCT
admet-1885	340	12	apixaban	apixaban	ADJ
admet-1885	340	13	,	,	PUNCT
admet-1885	340	14	bms-562247	bms-562247	NOUN
admet-1885	340	15	)	)	PUNCT
admet-1885	340	16	,	,	PUNCT
admet-1885	340	17	a	a	DET
admet-1885	340	18	highly	highly	ADV
admet-1885	340	19	potent	potent	ADJ
admet-1885	340	20	,	,	PUNCT
admet-1885	340	21	selective	selective	ADJ
admet-1885	340	22	,	,	PUNCT
admet-1885	340	23	efficacious	efficacious	ADJ
admet-1885	340	24	,	,	PUNCT
admet-1885	340	25	and	and	CCONJ
admet-1885	340	26	orally	orally	ADV
admet-1885	340	27	bioavailable	bioavailable	ADJ
admet-1885	340	28	inhibitor	inhibitor	NOUN
admet-1885	340	29	of	of	ADP
admet-1885	340	30	blood	blood	NOUN
admet-1885	340	31	coagulation	coagulation	NOUN
admet-1885	340	32	factor	factor	NOUN
admet-1885	340	33	xa	xa	PROPN
admet-1885	340	34	.	.	PROPN
admet-1885	340	35	journal	journal	PROPN
admet-1885	340	36	of	of	ADP
admet-1885	340	37	medicinal	medicinal	ADJ
admet-1885	340	38	chemistry	chemistry	NOUN
admet-1885	340	39	50	50	NUM
admet-1885	340	40	(	(	PUNCT
admet-1885	340	41	2007	2007	NUM
admet-1885	340	42	)	)	PUNCT
admet-1885	340	43	53395356	53395356	NUM
admet-1885	340	44	.	.	PUNCT
admet-1885	341	1	https://doi.org/10.1021/jm070245n	https://doi.org/10.1021/jm070245n	PUNCT
admet-1885	342	1	[	[	X
admet-1885	342	2	8	8	NUM
admet-1885	342	3	]	]	X
admet-1885	342	4	e.d	e.d	PROPN
admet-1885	342	5	.	.	PROPN
admet-1885	342	6	deeks	deek	NOUN
admet-1885	342	7	.	.	PUNCT
admet-1885	343	1	apixaban	apixaban	ADJ
admet-1885	343	2	.	.	PUNCT
admet-1885	344	1	drugs	drug	NOUN
admet-1885	344	2	72	72	NUM
admet-1885	344	3	(	(	PUNCT
admet-1885	344	4	2012	2012	NUM
admet-1885	344	5	)	)	PUNCT
admet-1885	344	6	1271	1271	NUM
admet-1885	344	7	-	-	SYM
admet-1885	344	8	1291	1291	NUM
admet-1885	344	9	.	.	PUNCT
admet-1885	345	1	https://doi.org/10.2165/11209020-000000000-00000	https://doi.org/10.2165/11209020-000000000-00000	X
admet-1885	346	1	[	[	X
admet-1885	346	2	9	9	NUM
admet-1885	346	3	]	]	X
admet-1885	346	4	y.	y.	NOUN
admet-1885	346	5	falck	falck	NOUN
admet-1885	346	6	-	-	PUNCT
admet-1885	346	7	ytter	ytter	NOUN
admet-1885	346	8	,	,	PUNCT
admet-1885	346	9	c.w	c.w	PROPN
admet-1885	346	10	.	.	PROPN
admet-1885	346	11	francis	francis	PROPN
admet-1885	346	12	,	,	PUNCT
admet-1885	346	13	n.a	n.a	PROPN
admet-1885	346	14	.	.	PROPN
admet-1885	346	15	johanson	johanson	PROPN
admet-1885	346	16	,	,	PUNCT
admet-1885	346	17	c.	c.	PROPN
admet-1885	346	18	curley	curley	PROPN
admet-1885	346	19	,	,	PUNCT
admet-1885	346	20	o.e	o.e	PROPN
admet-1885	346	21	.	.	PROPN
admet-1885	346	22	dahl	dahl	PROPN
admet-1885	346	23	,	,	PUNCT
admet-1885	346	24	s.	s.	PROPN
admet-1885	346	25	schulman	schulman	PROPN
admet-1885	346	26	,	,	PUNCT
admet-1885	346	27	t.l	t.l	PROPN
admet-1885	346	28	.	.	PROPN
admet-1885	346	29	ortel	ortel	PROPN
admet-1885	346	30	,	,	PUNCT
admet-1885	346	31	s.g	s.g	PROPN
admet-1885	346	32	.	.	PROPN
admet-1885	346	33	pauker	pauker	NOUN
admet-1885	346	34	,	,	PUNCT
admet-1885	346	35	c.w.c	c.w.c	VERB
admet-1885	346	36	.	.	PROPN
admet-1885	346	37	jr	jr	PROPN
admet-1885	346	38	.	.	PROPN
admet-1885	346	39	prevention	prevention	NOUN
admet-1885	346	40	of	of	ADP
admet-1885	346	41	vte	vte	NOUN
admet-1885	346	42	in	in	ADP
admet-1885	346	43	orthopedic	orthopedic	ADJ
admet-1885	346	44	surgery	surgery	NOUN
admet-1885	346	45	patients	patient	NOUN
admet-1885	346	46	:	:	PUNCT
admet-1885	346	47	antithrombotic	antithrombotic	ADJ
admet-1885	346	48	therapy	therapy	NOUN
admet-1885	346	49	and	and	CCONJ
admet-1885	346	50	prevention	prevention	NOUN
admet-1885	346	51	of	of	ADP
admet-1885	346	52	thrombosis	thrombosis	NOUN
admet-1885	346	53	:	:	PUNCT
admet-1885	346	54	american	american	PROPN
admet-1885	346	55	college	college	PROPN
admet-1885	346	56	of	of	ADP
admet-1885	346	57	chest	chest	NOUN
admet-1885	346	58	physicians	physician	NOUN
admet-1885	346	59	evidence	evidence	NOUN
admet-1885	346	60	-based	-base	VERB
admet-1885	346	61	clinical	clinical	ADJ
admet-1885	346	62	practice	practice	NOUN
admet-1885	346	63	guidelines	guideline	NOUN
admet-1885	346	64	.	.	PUNCT
admet-1885	347	1	chest	chest	NOUN
admet-1885	347	2	141	141	NUM
admet-1885	347	3	(	(	PUNCT
admet-1885	347	4	2012	2012	NUM
admet-1885	347	5	)	)	PUNCT
admet-1885	347	6	e278s	e278s	NOUN
admet-1885	347	7	-	-	PUNCT
admet-1885	347	8	e325s	e325s	NOUN
admet-1885	347	9	.	.	PUNCT
admet-1885	348	1	https://doi.org/10.1378/chest.11-2404	https://doi.org/10.1378/chest.11-2404	NOUN
admet-1885	349	1	[	[	X
admet-1885	349	2	10	10	NUM
admet-1885	349	3	]	]	X
admet-1885	349	4	p.c	p.c	PROPN
admet-1885	349	5	.	.	PROPN
admet-1885	349	6	wong	wong	PROPN
admet-1885	349	7	,	,	PUNCT
admet-1885	349	8	d.j	d.j	PROPN
admet-1885	349	9	.	.	PROPN
admet-1885	349	10	pinto	pinto	PROPN
admet-1885	349	11	,	,	PUNCT
admet-1885	349	12	d.	d.	PROPN
admet-1885	349	13	zhang	zhang	PROPN
admet-1885	349	14	.	.	PUNCT
admet-1885	350	1	d.	d.	PROPN
admet-1885	350	2	preclinical	preclinical	ADJ
admet-1885	350	3	discovery	discovery	PROPN
admet-1885	350	4	of	of	ADP
admet-1885	350	5	apixaban	apixaban	ADJ
admet-1885	350	6	,	,	PUNCT
admet-1885	350	7	a	a	DET
admet-1885	350	8	direct	direct	ADJ
admet-1885	350	9	and	and	CCONJ
admet-1885	350	10	orally	orally	ADV
admet-1885	350	11	bioavailable	bioavailable	ADJ
admet-1885	350	12	factor	factor	NOUN
admet-1885	350	13	xa	xa	PROPN
admet-1885	350	14	inhibitor	inhibitor	PROPN
admet-1885	350	15	.	.	PUNCT
admet-1885	351	1	journal	journal	NOUN
admet-1885	351	2	of	of	ADP
admet-1885	351	3	thrombosis	thrombosis	NOUN
admet-1885	351	4	and	and	CCONJ
admet-1885	351	5	thrombolysis	thrombolysis	NOUN
admet-1885	351	6	31	31	NUM
admet-1885	351	7	(	(	PUNCT
admet-1885	351	8	2011	2011	NUM
admet-1885	351	9	)	)	PUNCT
admet-1885	351	10	478	478	NUM
admet-1885	351	11	-	-	SYM
admet-1885	351	12	492	492	NUM
admet-1885	351	13	.	.	PUNCT
admet-1885	352	1	https://doi.org/	https://doi.org/	VERB
admet-1885	352	2	10.1007	10.1007	NUM
admet-1885	352	3	/	/	SYM
admet-1885	352	4	s11239	s11239	PROPN
admet-1885	352	5	-	-	PUNCT
admet-1885	352	6	011	011	NUM
admet-1885	352	7	-	-	PUNCT
admet-1885	352	8	0551	0551	NUM
admet-1885	352	9	-	-	SYM
admet-1885	352	10	3	3	NUM
admet-1885	353	1	[	[	X
admet-1885	353	2	11	11	NUM
admet-1885	353	3	]	]	X
admet-1885	353	4	h.	h.	PROPN
admet-1885	353	5	li	li	PROPN
admet-1885	353	6	,	,	PUNCT
admet-1885	353	7	a.	a.	NOUN
admet-1885	353	8	farajtabar	farajtabar	PROPN
admet-1885	353	9	,	,	PUNCT
admet-1885	353	10	y.	y.	PROPN
admet-1885	353	11	xie	xie	PROPN
admet-1885	353	12	,	,	PUNCT
admet-1885	353	13	z.	z.	PROPN
admet-1885	353	14	li	li	PROPN
admet-1885	353	15	,	,	PUNCT
admet-1885	353	16	h.	h.	PROPN
admet-1885	353	17	zhao	zhao	PROPN
admet-1885	353	18	.	.	PUNCT
admet-1885	354	1	apixaban	apixaban	PROPN
admet-1885	354	2	(	(	PUNCT
admet-1885	354	3	i	i	NOUN
admet-1885	354	4	)	)	PUNCT
admet-1885	354	5	in	in	ADP
admet-1885	354	6	several	several	ADJ
admet-1885	354	7	aqueous	aqueous	ADJ
admet-1885	354	8	co	co	ADJ
admet-1885	354	9	-	-	ADJ
admet-1885	354	10	solvent	solvent	ADJ
admet-1885	354	11	mixtures	mixture	NOUN
admet-1885	354	12	:	:	PUNCT
admet-1885	354	13	solubility	solubility	NOUN
admet-1885	354	14	,	,	PUNCT
admet-1885	354	15	solvent	solvent	ADJ
admet-1885	354	16	effect	effect	NOUN
admet-1885	354	17	and	and	CCONJ
admet-1885	354	18	preferential	preferential	ADJ
admet-1885	354	19	solvation	solvation	NOUN
admet-1885	354	20	.	.	PUNCT
admet-1885	355	1	the	the	DET
admet-1885	355	2	journal	journal	PROPN
admet-1885	355	3	of	of	ADP
admet-1885	355	4	chemical	chemical	ADJ
admet-1885	355	5	thermodynamics	thermodynamic	NOUN
admet-1885	355	6	150	150	NUM
admet-1885	355	7	(	(	PUNCT
admet-1885	355	8	2020	2020	NUM
admet-1885	355	9	)	)	PUNCT
admet-1885	355	10	106200	106200	NUM
admet-1885	355	11	.	.	PUNCT
admet-1885	356	1	https://doi.org/10.1016/j.jct.2020.106200	https://doi.org/10.1016/j.jct.2020.106200	PROPN
admet-1885	357	1	[	[	X
admet-1885	357	2	12	12	NUM
admet-1885	357	3	]	]	PUNCT
admet-1885	357	4	w.	w.	PROPN
admet-1885	357	5	byon	byon	PROPN
admet-1885	357	6	,	,	PUNCT
admet-1885	357	7	s.	s.	PROPN
admet-1885	357	8	garonzik	garonzik	PROPN
admet-1885	357	9	,	,	PUNCT
admet-1885	357	10	r.a	r.a	PROPN
admet-1885	357	11	.	.	PROPN
admet-1885	357	12	boyd	boyd	PROPN
admet-1885	357	13	,	,	PUNCT
admet-1885	357	14	c.e	c.e	PROPN
admet-1885	357	15	.	.	PROPN
admet-1885	357	16	frost	frost	NOUN
admet-1885	357	17	.	.	PUNCT
admet-1885	358	1	apixaban	apixaban	ADJ
admet-1885	358	2	:	:	PUNCT
admet-1885	358	3	a	a	DET
admet-1885	358	4	clinical	clinical	ADJ
admet-1885	358	5	pharmacokinetic	pharmacokinetic	ADJ
admet-1885	358	6	and	and	CCONJ
admet-1885	358	7	pharmacodynamic	pharmacodynamic	ADJ
admet-1885	358	8	review	review	NOUN
admet-1885	358	9	.	.	PUNCT
admet-1885	359	1	clinical	clinical	ADJ
admet-1885	359	2	pharmacokinetics	pharmacokinetic	NOUN
admet-1885	359	3	58	58	NUM
admet-1885	359	4	(	(	PUNCT
admet-1885	359	5	2019	2019	NUM
admet-1885	359	6	)	)	PUNCT
admet-1885	359	7	1265	1265	NUM
admet-1885	359	8	-	-	SYM
admet-1885	359	9	1279	1279	NUM
admet-1885	359	10	.	.	PUNCT
admet-1885	360	1	https://doi.org/10.1007/	https://doi.org/10.1007/	PROPN
admet-1885	360	2	s40262	s40262	PROPN
admet-1885	360	3	-	-	PUNCT
admet-1885	360	4	019	019	NUM
admet-1885	360	5	-	-	PUNCT
admet-1885	360	6	00775	00775	NUM
admet-1885	360	7	-	-	PUNCT
admet-1885	360	8	z	z	NOUN
admet-1885	360	9	https://doi.org/10.5599/admet.1885	https://doi.org/10.5599/admet.1885	PROPN
admet-1885	360	10	https://rjptonline.org/‌abstractview.aspx?pid=2009-2-2-46	https://rjptonline.org/‌abstractview.aspx?pid=2009-2-2-46	NOUN
admet-1885	360	11	https://rjptonline.org/‌abstractview.aspx?pid=2009-2-2-46	https://rjptonline.org/‌abstractview.aspx?pid=2009-2-2-46	NOUN
admet-1885	360	12	https://doi.org/10.1038/90761‏	https://doi.org/10.1038/90761‏	PROPN
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admet-1885	368	20	550	550	NUM
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admet-1885	374	9	-	-	PUNCT
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admet-1885	387	4	discovery	discovery	NOUN
admet-1885	387	5	3	3	NUM
admet-1885	387	6	(	(	PUNCT
admet-1885	387	7	2004	2004	NUM
admet-1885	387	8	)	)	PUNCT
admet-1885	387	9	1023	1023	NUM
admet-1885	387	10	-	-	SYM
admet-1885	387	11	1035	1035	NUM
admet-1885	387	12	.	.	PUNCT
admet-1885	388	1	https://doi.org/10.1038/nrd1576	https://doi.org/10.1038/nrd1576	PROPN
admet-1885	388	2	[	[	X
admet-1885	388	3	18	18	NUM
admet-1885	388	4	]	]	X
admet-1885	388	5	m.m	m.m	PROPN
admet-1885	388	6	.	.	PROPN
admet-1885	388	7	doile	doile	PROPN
admet-1885	388	8	,	,	PUNCT
admet-1885	388	9	k.a	k.a	PROPN
admet-1885	388	10	.	.	PUNCT
admet-1885	388	11	fortunato	fortunato	PROPN
admet-1885	388	12	,	,	PUNCT
admet-1885	388	13	i.c	i.c	PROPN
admet-1885	388	14	.	.	PROPN
admet-1885	388	15	schmücker	schmücker	PROPN
admet-1885	388	16	,	,	PUNCT
admet-1885	388	17	s.k	s.k	PROPN
admet-1885	388	18	.	.	PROPN
admet-1885	388	19	schucko	schucko	PROPN
admet-1885	388	20	,	,	PUNCT
admet-1885	388	21	m.a.s	m.a.s	PROPN
admet-1885	388	22	.	.	PROPN
admet-1885	388	23	silva	silva	PROPN
admet-1885	388	24	,	,	PUNCT
admet-1885	388	25	p.o	p.o	PROPN
admet-1885	388	26	.	.	PROPN
admet-1885	388	27	rodrigues	rodrigues	PROPN
admet-1885	388	28	.	.	PUNCT
admet-1885	389	1	physicochemical	physicochemical	ADJ
admet-1885	389	2	properties	property	NOUN
admet-1885	389	3	and	and	CCONJ
admet-1885	389	4	dissolution	dissolution	ADJ
admet-1885	389	5	studies	study	NOUN
admet-1885	389	6	of	of	ADP
admet-1885	389	7	dexamethasone	dexamethasone	NOUN
admet-1885	389	8	acetate	acetate	PROPN
admet-1885	389	9	-β	-β	PROPN
admet-1885	389	10	-	-	PUNCT
admet-1885	389	11	cyclodextrin	cyclodextrin	NOUN
admet-1885	389	12	inclusion	inclusion	NOUN
admet-1885	389	13	complexes	complex	NOUN
admet-1885	389	14	produced	produce	VERB
admet-1885	389	15	by	by	ADP
admet-1885	389	16	different	different	ADJ
admet-1885	389	17	methods	method	NOUN
admet-1885	389	18	.	.	PUNCT
admet-1885	390	1	aaps	aap	NOUN
admet-1885	390	2	pharmscitech	pharmscitech	VERB
admet-1885	390	3	9	9	NUM
admet-1885	390	4	(	(	PUNCT
admet-1885	390	5	2008	2008	NUM
admet-1885	390	6	)	)	PUNCT
admet-1885	390	7	314	314	NUM
admet-1885	390	8	-	-	SYM
admet-1885	390	9	322	322	NUM
admet-1885	390	10	.	.	PUNCT
admet-1885	391	1	https://doi.org/10.1208/s12249-008-9042-z	https://doi.org/10.1208/s12249-008-9042-z	PROPN
admet-1885	391	2	[	[	X
admet-1885	391	3	19	19	NUM
admet-1885	391	4	]	]	PUNCT
admet-1885	391	5	chemspider	chemspider	NOUN
admet-1885	391	6	database	database	PROPN
admet-1885	391	7	.	.	PUNCT
admet-1885	391	8	http://www.chemspider.com/	http://www.chemspider.com/	NOUN
admet-1885	391	9	(	(	PUNCT
admet-1885	391	10	accessed	access	VERB
admet-1885	391	11	date	date	NOUN
admet-1885	391	12	:	:	PUNCT
admet-1885	391	13	01/08/2023	01/08/2023	NUM
admet-1885	391	14	)	)	PUNCT
admet-1885	391	15	.	.	PUNCT
admet-1885	392	1	[	[	X
admet-1885	392	2	20	20	NUM
admet-1885	392	3	]	]	X
admet-1885	392	4	gaussian	gaussian	ADJ
admet-1885	392	5	09	09	NUM
admet-1885	392	6	,	,	PUNCT
admet-1885	392	7	revision	revision	NOUN
admet-1885	392	8	d.01	d.01	PROPN
admet-1885	392	9	,	,	PUNCT
admet-1885	392	10	m.j	m.j	PROPN
admet-1885	392	11	.	.	PROPN
admet-1885	392	12	frisch	frisch	PROPN
admet-1885	392	13	,	,	PUNCT
admet-1885	392	14	g.w	g.w	PROPN
admet-1885	392	15	.	.	PROPN
admet-1885	392	16	trucks	trucks	PROPN
admet-1885	392	17	,	,	PUNCT
admet-1885	392	18	h.b	h.b	PROPN
admet-1885	392	19	.	.	PROPN
admet-1885	392	20	schlegel	schlegel	PROPN
admet-1885	392	21	,	,	PUNCT
admet-1885	392	22	g.e	g.e	PROPN
admet-1885	392	23	.	.	PROPN
admet-1885	392	24	scuseria	scuseria	PROPN
admet-1885	392	25	,	,	PUNCT
admet-1885	392	26	m.a	m.a	PROPN
admet-1885	392	27	.	.	PROPN
admet-1885	392	28	robb	robb	PROPN
admet-1885	392	29	,	,	PUNCT
admet-1885	392	30	j.r	j.r	PROPN
admet-1885	392	31	.	.	PROPN
admet-1885	392	32	cheeseman	cheeseman	PROPN
admet-1885	392	33	,	,	PUNCT
admet-1885	392	34	g.	g.	PROPN
admet-1885	392	35	scalmani	scalmani	PROPN
admet-1885	392	36	,	,	PUNCT
admet-1885	392	37	v.	v.	PROPN
admet-1885	392	38	barone	barone	PROPN
admet-1885	392	39	,	,	PUNCT
admet-1885	392	40	b.	b.	PROPN
admet-1885	392	41	mennucci	mennucci	PROPN
admet-1885	392	42	,	,	PUNCT
admet-1885	392	43	g.a	g.a	PROPN
admet-1885	392	44	.	.	PROPN
admet-1885	392	45	petersson	petersson	PROPN
admet-1885	392	46	,	,	PUNCT
admet-1885	392	47	h.	h.	PROPN
admet-1885	392	48	nakatsuji	nakatsuji	PROPN
admet-1885	392	49	,	,	PUNCT
admet-1885	392	50	m.	m.	NOUN
admet-1885	392	51	caricato	caricato	PROPN
admet-1885	392	52	,	,	PUNCT
admet-1885	392	53	x.	x.	PROPN
admet-1885	392	54	li	li	PROPN
admet-1885	392	55	,	,	PUNCT
admet-1885	392	56	h.p	h.p	PROPN
admet-1885	392	57	.	.	PROPN
admet-1885	392	58	hratchian	hratchian	PROPN
admet-1885	392	59	,	,	PUNCT
admet-1885	392	60	a.f	a.f	PROPN
admet-1885	392	61	.	.	PROPN
admet-1885	392	62	izmaylov	izmaylov	PROPN
admet-1885	392	63	,	,	PUNCT
admet-1885	392	64	j.	j.	PROPN
admet-1885	392	65	bloino	bloino	PROPN
admet-1885	392	66	,	,	PUNCT
admet-1885	392	67	g.	g.	PROPN
admet-1885	392	68	zheng	zheng	PROPN
admet-1885	392	69	,	,	PUNCT
admet-1885	392	70	j.l	j.l	PROPN
admet-1885	392	71	.	.	PROPN
admet-1885	392	72	sonnenberg	sonnenberg	PROPN
admet-1885	392	73	,	,	PUNCT
admet-1885	392	74	m.	m.	PROPN
admet-1885	392	75	hada	hada	PROPN
admet-1885	392	76	,	,	PUNCT
admet-1885	392	77	m.	m.	NOUN
admet-1885	392	78	ehara	ehara	PROPN
admet-1885	392	79	,	,	PUNCT
admet-1885	392	80	k.	k.	PROPN
admet-1885	392	81	toyota	toyota	PROPN
admet-1885	392	82	,	,	PUNCT
admet-1885	392	83	r.	r.	PROPN
admet-1885	392	84	fukuda	fukuda	PROPN
admet-1885	392	85	,	,	PUNCT
admet-1885	392	86	j.	j.	PROPN
admet-1885	392	87	hasegawa	hasegawa	PROPN
admet-1885	392	88	,	,	PUNCT
admet-1885	392	89	m.	m.	PROPN
admet-1885	392	90	ishida	ishida	PROPN
admet-1885	392	91	,	,	PUNCT
admet-1885	392	92	t.	t.	PROPN
admet-1885	392	93	nakajima	nakajima	PROPN
admet-1885	392	94	,	,	PUNCT
admet-1885	392	95	y.	y.	PROPN
admet-1885	392	96	honda	honda	PROPN
admet-1885	392	97	,	,	PUNCT
admet-1885	392	98	o.	o.	PROPN
admet-1885	392	99	kitao	kitao	PROPN
admet-1885	392	100	,	,	PUNCT
admet-1885	392	101	h.	h.	PROPN
admet-1885	392	102	nakai	nakai	PROPN
admet-1885	392	103	,	,	PUNCT
admet-1885	392	104	t.	t.	PROPN
admet-1885	392	105	vreven	vreven	PROPN
admet-1885	392	106	,	,	PUNCT
admet-1885	392	107	j.a	j.a	PROPN
admet-1885	392	108	.	.	PROPN
admet-1885	392	109	montgomery	montgomery	PROPN
admet-1885	392	110	,	,	PUNCT
admet-1885	392	111	j.e	j.e	PROPN
admet-1885	392	112	.	.	PROPN
admet-1885	392	113	jr	jr	PROPN
admet-1885	392	114	.	.	PROPN
admet-1885	392	115	,	,	PUNCT
admet-1885	392	116	peralta	peralta	PROPN
admet-1885	392	117	,	,	PUNCT
admet-1885	392	118	f.	f.	PROPN
admet-1885	392	119	ogliaro	ogliaro	PROPN
admet-1885	392	120	,	,	PUNCT
admet-1885	392	121	m.	m.	NOUN
admet-1885	392	122	bearpark	bearpark	PROPN
admet-1885	392	123	,	,	PUNCT
admet-1885	392	124	j.j	j.j	PROPN
admet-1885	392	125	.	.	PROPN
admet-1885	392	126	heyd	heyd	PROPN
admet-1885	392	127	,	,	PUNCT
admet-1885	392	128	e.	e.	PROPN
admet-1885	392	129	brothers	brothers	PROPN
admet-1885	392	130	,	,	PUNCT
admet-1885	392	131	k.n	k.n	PROPN
admet-1885	392	132	.	.	PROPN
admet-1885	392	133	kudin	kudin	PROPN
admet-1885	392	134	,	,	PUNCT
admet-1885	392	135	v.n	v.n	PROPN
admet-1885	392	136	.	.	PROPN
admet-1885	392	137	staroverov	staroverov	PROPN
admet-1885	392	138	,	,	PUNCT
admet-1885	392	139	r.	r.	PROPN
admet-1885	392	140	kobayashi	kobayashi	PROPN
admet-1885	392	141	,	,	PUNCT
admet-1885	392	142	j.	j.	PROPN
admet-1885	392	143	normand	normand	PROPN
admet-1885	392	144	,	,	PUNCT
admet-1885	392	145	k.	k.	PROPN
admet-1885	392	146	raghavachari	raghavachari	PROPN
admet-1885	392	147	,	,	PUNCT
admet-1885	392	148	a.	a.	NOUN
admet-1885	392	149	rendell	rendell	PROPN
admet-1885	392	150	,	,	PUNCT
admet-1885	392	151	j.c	j.c	PROPN
admet-1885	392	152	.	.	PROPN
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admet-1885	392	154	,	,	PUNCT
admet-1885	392	155	s.s	s.s	PROPN
admet-1885	392	156	.	.	PROPN
admet-1885	392	157	iyengar	iyengar	PROPN
admet-1885	392	158	,	,	PUNCT
admet-1885	392	159	j.	j.	PROPN
admet-1885	392	160	tomasi	tomasi	PROPN
admet-1885	392	161	,	,	PUNCT
admet-1885	392	162	m.	m.	NOUN
admet-1885	392	163	cossi	cossi	PROPN
admet-1885	392	164	,	,	PUNCT
admet-1885	392	165	n.	n.	PROPN
admet-1885	392	166	rega	rega	PROPN
admet-1885	392	167	,	,	PUNCT
admet-1885	392	168	j.m	j.m	PROPN
admet-1885	392	169	.	.	PROPN
admet-1885	392	170	millam	millam	PROPN
admet-1885	392	171	,	,	PUNCT
admet-1885	392	172	m.	m.	NOUN
admet-1885	392	173	klene	klene	PROPN
admet-1885	392	174	,	,	PUNCT
admet-1885	392	175	j.e	j.e	PROPN
admet-1885	392	176	.	.	PROPN
admet-1885	392	177	knox	knox	PROPN
admet-1885	392	178	,	,	PUNCT
admet-1885	392	179	j.b	j.b	PROPN
admet-1885	392	180	.	.	PROPN
admet-1885	392	181	cross	cross	PROPN
admet-1885	392	182	,	,	PUNCT
admet-1885	392	183	v.	v.	PROPN
admet-1885	392	184	bakken	bakken	PROPN
admet-1885	392	185	,	,	PUNCT
admet-1885	392	186	c.	c.	PROPN
admet-1885	392	187	adamo	adamo	PROPN
admet-1885	392	188	,	,	PUNCT
admet-1885	392	189	j.	j.	PROPN
admet-1885	392	190	jaramillo	jaramillo	PROPN
admet-1885	392	191	,	,	PUNCT
admet-1885	392	192	r.	r.	PROPN
admet-1885	392	193	gomperts	gomperts	PROPN
admet-1885	392	194	,	,	PUNCT
admet-1885	392	195	r.e	r.e	PROPN
admet-1885	392	196	.	.	PROPN
admet-1885	392	197	stratmann	stratmann	PROPN
admet-1885	392	198	,	,	PUNCT
admet-1885	392	199	o.	o.	PROPN
admet-1885	392	200	yazyev	yazyev	PROPN
admet-1885	392	201	,	,	PUNCT
admet-1885	392	202	a.j	a.j	PROPN
admet-1885	392	203	.	.	PROPN
admet-1885	392	204	austin	austin	PROPN
admet-1885	392	205	,	,	PUNCT
admet-1885	392	206	r.	r.	PROPN
admet-1885	392	207	cammi	cammi	PROPN
admet-1885	392	208	,	,	PUNCT
admet-1885	392	209	c.	c.	PROPN
admet-1885	392	210	pomelli	pomelli	PROPN
admet-1885	392	211	,	,	PUNCT
admet-1885	392	212	j.w	j.w	PROPN
admet-1885	392	213	.	.	PROPN
admet-1885	392	214	ochterski	ochterski	PROPN
admet-1885	392	215	,	,	PUNCT
admet-1885	392	216	r.l	r.l	PROPN
admet-1885	392	217	.	.	PROPN
admet-1885	392	218	martin	martin	PROPN
admet-1885	392	219	,	,	PUNCT
admet-1885	392	220	k.	k.	PROPN
admet-1885	392	221	morokuma	morokuma	PROPN
admet-1885	392	222	,	,	PUNCT
admet-1885	392	223	v.g	v.g	PROPN
admet-1885	392	224	.	.	PROPN
admet-1885	392	225	zakrzewski	zakrzewski	PROPN
admet-1885	392	226	,	,	PUNCT
admet-1885	392	227	g.a	g.a	PROPN
admet-1885	392	228	.	.	PROPN
admet-1885	392	229	voth	voth	PROPN
admet-1885	392	230	,	,	PUNCT
admet-1885	392	231	p.	p.	PROPN
admet-1885	392	232	salvador	salvador	PROPN
admet-1885	392	233	,	,	PUNCT
admet-1885	392	234	j.j	j.j	PROPN
admet-1885	392	235	.	.	PROPN
admet-1885	392	236	dannenberg	dannenberg	PROPN
admet-1885	392	237	,	,	PUNCT
admet-1885	392	238	s.	s.	PROPN
admet-1885	392	239	dapprich	dapprich	PROPN
admet-1885	392	240	,	,	PUNCT
admet-1885	392	241	a.d	a.d	PROPN
admet-1885	392	242	.	.	PROPN
admet-1885	392	243	daniels	daniels	PROPN
admet-1885	392	244	,	,	PUNCT
admet-1885	392	245	ö.farkas	ö.farkas	PROPN
admet-1885	392	246	,	,	PUNCT
admet-1885	392	247	j.b	j.b	PROPN
admet-1885	392	248	.	.	PUNCT
admet-1885	392	249	foresman	foresman	PROPN
admet-1885	392	250	,	,	PUNCT
admet-1885	392	251	j.v	j.v	PROPN
admet-1885	392	252	.	.	PROPN
admet-1885	392	253	ortiz	ortiz	PROPN
admet-1885	392	254	,	,	PUNCT
admet-1885	392	255	j.	j.	PROPN
admet-1885	392	256	cioslowski	cioslowski	PROPN
admet-1885	392	257	,	,	PUNCT
admet-1885	392	258	d.j	d.j	PROPN
admet-1885	392	259	.	.	PROPN
admet-1885	392	260	and	and	CCONJ
admet-1885	392	261	fox	fox	PROPN
admet-1885	392	262	.	.	PUNCT
admet-1885	393	1	gaussian	gaussian	PROPN
admet-1885	393	2	,	,	PUNCT
admet-1885	393	3	inc	inc	PROPN
admet-1885	393	4	.	.	PROPN
admet-1885	393	5	,	,	PUNCT
admet-1885	393	6	wallingford	wallingford	PROPN
admet-1885	393	7	ct	ct	PROPN
admet-1885	393	8	,	,	PUNCT
admet-1885	393	9	2009	2009	NUM
admet-1885	393	10	.	.	PUNCT
admet-1885	394	1	https://www.scienceopen.com/document?vid=839f33cc-9114-4a55-8f1a-3f1520324ef5	https://www.scienceopen.com/document?vid=839f33cc-9114-4a55-8f1a-3f1520324ef5	ADP
admet-1885	394	2	[	[	X
admet-1885	394	3	21	21	NUM
admet-1885	394	4	]	]	X
admet-1885	394	5	apixaban	apixaban	NOUN
admet-1885	394	6	in	in	ADP
admet-1885	394	7	:	:	PUNCT
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admet-1885	394	9	(	(	PUNCT
admet-1885	394	10	accessed	access	VERB
admet-1885	394	11	date	date	NOUN
admet-1885	394	12	:	:	PUNCT
admet-1885	394	13	20/04/2023	20/04/2023	NUM
admet-1885	394	14	)	)	PUNCT
admet-1885	394	15	.	.	PUNCT
admet-1885	395	1	[	[	X
admet-1885	395	2	22	22	NUM
admet-1885	395	3	]	]	X
admet-1885	395	4	y.	y.	PROPN
admet-1885	395	5	chen	chen	PROPN
admet-1885	395	6	,	,	PUNCT
admet-1885	395	7	l.	l.	PROPN
admet-1885	395	8	li	li	PROPN
admet-1885	395	9	,	,	PUNCT
admet-1885	395	10	j.	j.	PROPN
admet-1885	395	11	yao	yao	PROPN
admet-1885	395	12	,	,	PUNCT
admet-1885	395	13	y.y	y.y	PROPN
admet-1885	395	14	.	.	PROPN
admet-1885	395	15	ma	ma	PROPN
admet-1885	395	16	,	,	PUNCT
admet-1885	395	17	j.m	j.m	PROPN
admet-1885	395	18	.	.	PROPN
admet-1885	395	19	chen	chen	PROPN
admet-1885	395	20	,	,	PUNCT
admet-1885	395	21	t.b	t.b	PROPN
admet-1885	395	22	.	.	PROPN
admet-1885	395	23	lu	lu	PROPN
admet-1885	395	24	.	.	PUNCT
admet-1885	396	1	improving	improve	VERB
admet-1885	396	2	the	the	DET
admet-1885	396	3	solubility	solubility	NOUN
admet-1885	396	4	and	and	CCONJ
admet-1885	396	5	bioavailability	bioavailability	NOUN
admet-1885	396	6	of	of	ADP
admet-1885	396	7	apixaban	apixaban	NOUN
admet-1885	396	8	via	via	ADP
admet-1885	396	9	apixaban	apixaban	ADJ
admet-1885	396	10	–	–	PUNCT
admet-1885	396	11	oxalic	oxalic	ADJ
admet-1885	396	12	acid	acid	NOUN
admet-1885	396	13	cocrystal	cocrystal	PROPN
admet-1885	396	14	.	.	PUNCT
admet-1885	397	1	crystal	crystal	NOUN
admet-1885	397	2	growth	growth	NOUN
admet-1885	397	3	and	and	CCONJ
admet-1885	397	4	design	design	NOUN
admet-1885	397	5	16	16	NUM
admet-1885	397	6	(	(	PUNCT
admet-1885	397	7	2016	2016	NUM
admet-1885	397	8	)	)	PUNCT
admet-1885	397	9	2923	2923	NUM
admet-1885	397	10	-	-	SYM
admet-1885	397	11	2930	2930	NUM
admet-1885	397	12	.	.	PUNCT
admet-1885	398	1	https://doi.org/10.1021/acs.cgd.6b00266	https://doi.org/10.1021/acs.cgd.6b00266	NOUN
admet-1885	398	2	[	[	X
admet-1885	398	3	23	23	NUM
admet-1885	398	4	]	]	PUNCT
admet-1885	398	5	s.	s.	PROPN
admet-1885	398	6	sip	sip	PROPN
admet-1885	398	7	,	,	PUNCT
admet-1885	398	8	a.	a.	PROPN
admet-1885	398	9	gościniak	gościniak	PROPN
admet-1885	398	10	,	,	PUNCT
admet-1885	398	11	p.	p.	PROPN
admet-1885	398	12	szulc	szulc	PROPN
admet-1885	398	13	,	,	PUNCT
admet-1885	398	14	j.	j.	PROPN
admet-1885	398	15	walkowiak	walkowiak	PROPN
admet-1885	398	16	,	,	PUNCT
admet-1885	398	17	j.	j.	PROPN
admet-1885	398	18	cielecka	cielecka	PROPN
admet-1885	398	19	-	-	PUNCT
admet-1885	398	20	piontek	piontek	PROPN
admet-1885	398	21	,	,	PUNCT
admet-1885	398	22	j.	j.	PROPN
admet-1885	398	23	assisted	assist	VERB
admet-1885	398	24	extraction	extraction	NOUN
admet-1885	398	25	with	with	ADP
admet-1885	398	26	cyclodextrins	cyclodextrin	NOUN
admet-1885	398	27	as	as	ADP
admet-1885	398	28	a	a	DET
admet-1885	398	29	way	way	NOUN
admet-1885	398	30	of	of	ADP
admet-1885	398	31	improving	improve	VERB
admet-1885	398	32	the	the	DET
admet-1885	398	33	antidiabetic	antidiabetic	ADJ
admet-1885	398	34	activity	activity	NOUN
admet-1885	398	35	of	of	ADP
admet-1885	398	36	actinidia	actinidia	PROPN
admet-1885	398	37	leaves	leave	NOUN
admet-1885	398	38	.	.	PUNCT
admet-1885	399	1	pharmaceutics	pharmaceutic	NOUN
admet-1885	399	2	14	14	NUM
admet-1885	399	3	(	(	PUNCT
admet-1885	399	4	2022	2022	NUM
admet-1885	399	5	)	)	PUNCT
admet-1885	399	6	2473	2473	NUM
admet-1885	399	7	.	.	PUNCT
admet-1885	400	1	https://doi.org/10.3390/pharmaceutics14112473	https://doi.org/10.3390/pharmaceutics14112473	PROPN
admet-1885	400	2	©	©	PROPN
admet-1885	400	3	2023	2023	NUM
admet-1885	400	4	by	by	ADP
admet-1885	400	5	the	the	DET
admet-1885	400	6	authors	author	NOUN
admet-1885	400	7	;	;	PUNCT
admet-1885	400	8	licensee	licensee	PROPN
admet-1885	400	9	iapc	iapc	PROPN
admet-1885	400	10	,	,	PUNCT
admet-1885	400	11	zagreb	zagreb	PROPN
admet-1885	400	12	,	,	PUNCT
admet-1885	400	13	croatia	croatia	PROPN
admet-1885	400	14	.	.	PUNCT
admet-1885	401	1	this	this	DET
admet-1885	401	2	article	article	NOUN
admet-1885	401	3	is	be	AUX
admet-1885	401	4	an	an	DET
admet-1885	401	5	open	open	ADJ
admet-1885	401	6	-	-	PUNCT
admet-1885	401	7	access	access	NOUN
admet-1885	401	8	article	article	NOUN
admet-1885	401	9	distributed	distribute	VERB
admet-1885	401	10	under	under	ADP
admet-1885	401	11	the	the	DET
admet-1885	401	12	terms	term	NOUN
admet-1885	401	13	and	and	CCONJ
admet-1885	401	14	conditions	condition	NOUN
admet-1885	401	15	of	of	ADP
admet-1885	401	16	the	the	DET
admet-1885	401	17	creative	creative	ADJ
admet-1885	401	18	commons	common	NOUN
admet-1885	401	19	attribution	attribution	NOUN
admet-1885	401	20	license	license	NOUN
admet-1885	401	21	(	(	PUNCT
admet-1885	401	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	NOUN
admet-1885	401	23	)	)	PUNCT
admet-1885	401	24	https://doi.org/10.1124/‌dmd.112.050260	https://doi.org/10.1124/‌dmd.112.050260	NOUN
admet-1885	401	25	https://doi.org/10.1124/‌dmd.112.050260	https://doi.org/10.1124/‌dmd.112.050260	NOUN
admet-1885	401	26	https://doi.org/10.1124/dmd.112.050260	https://doi.org/10.1124/dmd.112.050260	ADV
admet-1885	401	27	https://doi.org/10.1186/1477-9560-11-27	https://doi.org/10.1186/1477-9560-11-27	PROPN
admet-1885	401	28	https://doi.org/10.1124/dmd.108.025593	https://doi.org/10.1124/dmd.108.025593	ADP
admet-1885	401	29	https://doi.org/10.1038/nrd1576	https://doi.org/10.1038/nrd1576	ADJ
admet-1885	401	30	https://doi.org/10.1208/s12249-008-9042-z	https://doi.org/10.1208/s12249-008-9042-z	PROPN
admet-1885	401	31	http://www.chemspider.com/	http://www.chemspider.com/	NOUN
admet-1885	402	1	https://www.scienceopen.com/document?vid=839f33cc-9114-4a55-8f1a-3f1520324ef5	https://www.scienceopen.com/document?vid=839f33cc-9114-4a55-8f1a-3f1520324ef5	PROPN
admet-1885	402	2	https://www.rxlist.com/eliquis-drug.htm	https://www.rxlist.com/eliquis-drug.htm	PROPN
admet-1885	402	3	https://doi.org/10.1021/acs.cgd.6b00266	https://doi.org/10.1021/acs.cgd.6b00266	NOUN
admet-1885	402	4	https://doi.org/10.3390/pharmaceutics14112473	https://doi.org/10.3390/pharmaceutics14112473	NOUN
admet-1885	402	5	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN