id	sid	tid	token	lemma	pos
admet-189	1	1	manuscript	manuscript	PROPN
admet-189	1	2	doi	doi	PROPN
admet-189	1	3	:	:	PUNCT
admet-189	1	4	10.5599	10.5599	NUM
admet-189	1	5	/	/	SYM
admet-189	1	6	admet.3.3.189	admet.3.3.189	ADP
admet-189	1	7	155	155	NUM
admet-189	1	8	admet	admet	X
admet-189	1	9	&	&	CCONJ
admet-189	1	10	dmpk	dmpk	PROPN
admet-189	1	11	3(3	3(3	NUM
admet-189	1	12	)	)	PUNCT
admet-189	1	13	(	(	PUNCT
admet-189	1	14	2015	2015	NUM
admet-189	1	15	)	)	PUNCT
admet-189	1	16	155	155	NUM
admet-189	1	17	-	-	SYM
admet-189	1	18	181	181	NUM
admet-189	1	19	;	;	PUNCT
admet-189	1	20	doi	doi	NOUN
admet-189	1	21	:	:	PUNCT
admet-189	1	22	10.5599	10.5599	NUM
admet-189	1	23	/	/	SYM
admet-189	1	24	admet.3.3.189	admet.3.3.189	ADP
admet-189	1	25	open	open	ADJ
admet-189	1	26	access	access	NOUN
admet-189	1	27	:	:	PUNCT
admet-189	1	28	issn	issn	PROPN
admet-189	1	29	:	:	PUNCT
admet-189	1	30	1848	1848	NUM
admet-189	1	31	-	-	SYM
admet-189	1	32	7718	7718	NUM
admet-189	1	33	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-189	1	34	review	review	NOUN
admet-189	1	35	nanotechnology	nanotechnology	NOUN
admet-189	1	36	platforms	platform	NOUN
admet-189	1	37	in	in	ADP
admet-189	1	38	parkinson	parkinson	NOUN
admet-189	1	39	’s	’s	PART
admet-189	1	40	disease	disease	NOUN
admet-189	1	41	rishi	rishi	PROPN
admet-189	1	42	rajat	rajat	PROPN
admet-189	1	43	adhikary1	adhikary1	PROPN
admet-189	1	44	,	,	PUNCT
admet-189	1	45	puja	puja	PROPN
admet-189	1	46	sandbhor1	sandbhor1	PROPN
admet-189	1	47	and	and	CCONJ
admet-189	1	48	rinti	rinti	PROPN
admet-189	1	49	banerjee	banerjee	PROPN
admet-189	1	50	*	*	PROPN
admet-189	1	51	1	1	NUM
admet-189	1	52	research	research	NOUN
admet-189	1	53	scholar	scholar	NOUN
admet-189	1	54	,	,	PUNCT
admet-189	1	55	department	department	NOUN
admet-189	1	56	of	of	ADP
admet-189	1	57	biosciences	bioscience	NOUN
admet-189	1	58	and	and	CCONJ
admet-189	1	59	bioengineering	bioengineering	NOUN
admet-189	1	60	,	,	PUNCT
admet-189	1	61	indian	indian	PROPN
admet-189	1	62	institute	institute	PROPN
admet-189	1	63	of	of	ADP
admet-189	1	64	technology	technology	PROPN
admet-189	1	65	bombay	bombay	PROPN
admet-189	1	66	,	,	PUNCT
admet-189	1	67	powai	powai	PROPN
admet-189	1	68	,	,	PUNCT
admet-189	1	69	mumbai	mumbai	PROPN
admet-189	1	70	,	,	PUNCT
admet-189	1	71	india400076	india400076	PROPN
admet-189	1	72	.	.	PUNCT
admet-189	2	1	both	both	DET
admet-189	2	2	authors	author	NOUN
admet-189	2	3	contributed	contribute	VERB
admet-189	2	4	equally	equally	ADV
admet-189	2	5	to	to	ADP
admet-189	2	6	the	the	DET
admet-189	2	7	writing	writing	NOUN
admet-189	2	8	of	of	ADP
admet-189	2	9	this	this	DET
admet-189	2	10	review	review	NOUN
admet-189	2	11	paper	paper	NOUN
admet-189	2	12	.	.	PUNCT
admet-189	3	1	*	*	PUNCT
admet-189	3	2	department	department	PROPN
admet-189	3	3	of	of	ADP
admet-189	3	4	biosciences	bioscience	NOUN
admet-189	3	5	and	and	CCONJ
admet-189	3	6	bioengineering	bioengineering	NOUN
admet-189	3	7	,	,	PUNCT
admet-189	3	8	indian	indian	PROPN
admet-189	3	9	institute	institute	PROPN
admet-189	3	10	of	of	ADP
admet-189	3	11	technology	technology	PROPN
admet-189	3	12	bombay	bombay	PROPN
admet-189	3	13	,	,	PUNCT
admet-189	3	14	powai	powai	PROPN
admet-189	3	15	,	,	PUNCT
admet-189	3	16	mumbai	mumbai	PROPN
admet-189	3	17	,	,	PUNCT
admet-189	3	18	india400076	india400076	PROPN
admet-189	3	19	.	.	PUNCT
admet-189	4	1	*	*	PUNCT
admet-189	4	2	corresponding	correspond	VERB
admet-189	4	3	author	author	NOUN
admet-189	4	4	:	:	PUNCT
admet-189	4	5	e	e	NOUN
admet-189	4	6	-	-	NOUN
admet-189	4	7	mail	mail	NOUN
admet-189	4	8	:	:	PUNCT
admet-189	4	9	rinti@iitb.ac.in	rinti@iitb.ac.in	ADV
admet-189	4	10	;	;	PUNCT
admet-189	4	11	tel	tel	PROPN
admet-189	4	12	.	.	PROPN
admet-189	4	13	:	:	PUNCT
admet-189	5	1	+912225767868	+912225767868	NUM
admet-189	5	2	;	;	PUNCT
admet-189	5	3	fax	fax	NOUN
admet-189	5	4	:	:	PUNCT
admet-189	5	5	+912225723480	+912225723480	NUM
admet-189	5	6	received	receive	VERB
admet-189	5	7	:	:	PUNCT
admet-189	5	8	june	june	PROPN
admet-189	5	9	04	04	NUM
admet-189	5	10	,	,	PUNCT
admet-189	5	11	2015	2015	NUM
admet-189	5	12	;	;	PUNCT
admet-189	5	13	revised	revise	VERB
admet-189	5	14	:	:	PUNCT
admet-189	5	15	august	august	PROPN
admet-189	5	16	21	21	NUM
admet-189	5	17	,	,	PUNCT
admet-189	5	18	2015	2015	NUM
admet-189	5	19	;	;	PUNCT
admet-189	5	20	published	publish	VERB
admet-189	5	21	:	:	PUNCT
admet-189	5	22	september	september	PROPN
admet-189	5	23	05	05	NUM
admet-189	5	24	,	,	PUNCT
admet-189	5	25	2015	2015	NUM
admet-189	5	26	abstract	abstract	ADJ
admet-189	5	27	parkinson	parkinson	NOUN
admet-189	5	28	’s	’s	PART
admet-189	5	29	disease	disease	NOUN
admet-189	5	30	(	(	PUNCT
admet-189	5	31	pd	pd	NOUN
admet-189	5	32	)	)	PUNCT
admet-189	5	33	remains	remain	VERB
admet-189	5	34	a	a	DET
admet-189	5	35	serious	serious	ADJ
admet-189	5	36	concern	concern	NOUN
admet-189	5	37	due	due	ADP
admet-189	5	38	to	to	ADP
admet-189	5	39	its	its	PRON
admet-189	5	40	effects	effect	NOUN
admet-189	5	41	on	on	ADP
admet-189	5	42	the	the	DET
admet-189	5	43	quality	quality	NOUN
admet-189	5	44	of	of	ADP
admet-189	5	45	life	life	NOUN
admet-189	5	46	of	of	ADP
admet-189	5	47	patients	patient	NOUN
admet-189	5	48	and	and	CCONJ
admet-189	5	49	its	its	PRON
admet-189	5	50	socioeconomic	socioeconomic	ADJ
admet-189	5	51	burden	burden	NOUN
admet-189	5	52	to	to	ADP
admet-189	5	53	society	society	NOUN
admet-189	5	54	.	.	PUNCT
admet-189	6	1	present	present	ADJ
admet-189	6	2	day	day	NOUN
admet-189	6	3	management	management	NOUN
admet-189	6	4	of	of	ADP
admet-189	6	5	pd	pd	PROPN
admet-189	6	6	has	have	VERB
admet-189	6	7	limitations	limitation	NOUN
admet-189	6	8	in	in	ADP
admet-189	6	9	both	both	DET
admet-189	6	10	diagnosis	diagnosis	NOUN
admet-189	6	11	and	and	CCONJ
admet-189	6	12	treatment	treatment	NOUN
admet-189	6	13	.	.	PUNCT
admet-189	7	1	nanotechnology	nanotechnology	PROPN
admet-189	7	2	may	may	AUX
admet-189	7	3	provide	provide	VERB
admet-189	7	4	smart	smart	ADJ
admet-189	7	5	solutions	solution	NOUN
admet-189	7	6	to	to	ADP
admet-189	7	7	this	this	DET
admet-189	7	8	problem	problem	NOUN
admet-189	7	9	.	.	PUNCT
admet-189	8	1	the	the	DET
admet-189	8	2	present	present	ADJ
admet-189	8	3	review	review	NOUN
admet-189	8	4	highlights	highlight	VERB
admet-189	8	5	the	the	DET
admet-189	8	6	recent	recent	ADJ
admet-189	8	7	advancements	advancement	NOUN
admet-189	8	8	in	in	ADP
admet-189	8	9	the	the	DET
admet-189	8	10	development	development	NOUN
admet-189	8	11	of	of	ADP
admet-189	8	12	nanotechnology	nanotechnology	NOUN
admet-189	8	13	platforms	platform	NOUN
admet-189	8	14	for	for	ADP
admet-189	8	15	pd	pd	PROPN
admet-189	8	16	.	.	PUNCT
admet-189	9	1	the	the	DET
admet-189	9	2	review	review	NOUN
admet-189	9	3	focuses	focus	VERB
admet-189	9	4	on	on	ADP
admet-189	9	5	the	the	DET
admet-189	9	6	use	use	NOUN
admet-189	9	7	of	of	ADP
admet-189	9	8	such	such	ADJ
admet-189	9	9	platforms	platform	NOUN
admet-189	9	10	in	in	ADP
admet-189	9	11	diagnostics	diagnostic	NOUN
admet-189	9	12	,	,	PUNCT
admet-189	9	13	treatments	treatment	NOUN
admet-189	9	14	,	,	PUNCT
admet-189	9	15	deep	deep	ADJ
admet-189	9	16	brain	brain	NOUN
admet-189	9	17	stimulation	stimulation	NOUN
admet-189	9	18	,	,	PUNCT
admet-189	9	19	neurosurgery	neurosurgery	NOUN
admet-189	9	20	and	and	CCONJ
admet-189	9	21	other	other	ADJ
admet-189	9	22	modalities	modality	NOUN
admet-189	9	23	of	of	ADP
admet-189	9	24	management	management	NOUN
admet-189	9	25	and	and	CCONJ
admet-189	9	26	the	the	DET
admet-189	9	27	role	role	NOUN
admet-189	9	28	of	of	ADP
admet-189	9	29	nanotechnology	nanotechnology	NOUN
admet-189	9	30	in	in	ADP
admet-189	9	31	each	each	PRON
admet-189	9	32	of	of	ADP
admet-189	9	33	these	these	DET
admet-189	9	34	fields	field	NOUN
admet-189	9	35	.	.	PUNCT
admet-189	10	1	the	the	DET
admet-189	10	2	review	review	NOUN
admet-189	10	3	also	also	ADV
admet-189	10	4	sheds	shed	VERB
admet-189	10	5	light	light	NOUN
admet-189	10	6	on	on	ADP
admet-189	10	7	the	the	DET
admet-189	10	8	translation	translation	NOUN
admet-189	10	9	of	of	ADP
admet-189	10	10	technologies	technology	NOUN
admet-189	10	11	from	from	ADP
admet-189	10	12	labs	lab	NOUN
admet-189	10	13	to	to	ADP
admet-189	10	14	clinics	clinic	NOUN
admet-189	10	15	and	and	CCONJ
admet-189	10	16	the	the	DET
admet-189	10	17	essential	essential	ADJ
admet-189	10	18	advantages	advantage	NOUN
admet-189	10	19	as	as	ADV
admet-189	10	20	well	well	ADV
admet-189	10	21	as	as	ADP
admet-189	10	22	concerns	concern	NOUN
admet-189	10	23	that	that	PRON
admet-189	10	24	accompany	accompany	VERB
admet-189	10	25	the	the	DET
admet-189	10	26	translation	translation	NOUN
admet-189	10	27	.	.	PUNCT
admet-189	11	1	keywords	keyword	VERB
admet-189	11	2	smart	smart	ADJ
admet-189	11	3	materials	material	NOUN
admet-189	11	4	;	;	PUNCT
admet-189	11	5	nanoparticles	nanoparticle	NOUN
admet-189	11	6	;	;	PUNCT
admet-189	11	7	sensors	sensor	NOUN
admet-189	11	8	;	;	PUNCT
admet-189	11	9	nanotechnology	nanotechnology	NOUN
admet-189	11	10	;	;	PUNCT
admet-189	11	11	drug	drug	NOUN
admet-189	11	12	delivery	delivery	NOUN
admet-189	11	13	;	;	PUNCT
admet-189	11	14	blood	blood	NOUN
admet-189	11	15	brain	brain	NOUN
admet-189	11	16	barrier	barrier	NOUN
admet-189	11	17	.	.	PUNCT
admet-189	12	1	_	_	PUNCT
admet-189	13	1	_	_	PUNCT
admet-189	14	1	_	_	PUNCT
admet-189	15	1	_	_	PUNCT
admet-189	16	1	_	_	PUNCT
admet-189	17	1	_	_	PUNCT
admet-189	18	1	_	_	PUNCT
admet-189	19	1	_	_	PUNCT
admet-189	20	1	_	_	PUNCT
admet-189	21	1	_	_	PUNCT
admet-189	22	1	_	_	PUNCT
admet-189	23	1	_	_	PUNCT
admet-189	24	1	_	_	PUNCT
admet-189	25	1	_	_	PUNCT
admet-189	26	1	_	_	PUNCT
admet-189	27	1	_	_	PUNCT
admet-189	28	1	_	_	PUNCT
admet-189	29	1	_	_	PUNCT
admet-189	30	1	_	_	PUNCT
admet-189	31	1	_	_	PUNCT
admet-189	32	1	_	_	PUNCT
admet-189	33	1	_	_	PUNCT
admet-189	34	1	_	_	PUNCT
admet-189	35	1	_	_	PUNCT
admet-189	36	1	_	_	PUNCT
admet-189	37	1	_	_	PUNCT
admet-189	38	1	_	_	PUNCT
admet-189	39	1	_	_	PUNCT
admet-189	40	1	_	_	PUNCT
admet-189	41	1	_	_	PUNCT
admet-189	42	1	_	_	PUNCT
admet-189	43	1	_	_	PUNCT
admet-189	44	1	_	_	PUNCT
admet-189	45	1	_	_	PUNCT
admet-189	46	1	_	_	PUNCT
admet-189	47	1	_	_	PUNCT
admet-189	48	1	_	_	PUNCT
admet-189	49	1	_	_	PUNCT
admet-189	50	1	_	_	PUNCT
admet-189	51	1	_	_	PUNCT
admet-189	52	1	_	_	PUNCT
admet-189	53	1	_	_	PUNCT
admet-189	54	1	_	_	PUNCT
admet-189	55	1	_	_	PUNCT
admet-189	56	1	_	_	PUNCT
admet-189	57	1	_	_	PUNCT
admet-189	58	1	_	_	PUNCT
admet-189	59	1	_	_	PUNCT
admet-189	60	1	_	_	PUNCT
admet-189	61	1	_	_	PUNCT
admet-189	62	1	_	_	PUNCT
admet-189	63	1	_	_	PUNCT
admet-189	64	1	_	_	PUNCT
admet-189	65	1	_	_	PUNCT
admet-189	66	1	_	_	PUNCT
admet-189	67	1	_	_	PUNCT
admet-189	68	1	_	_	PUNCT
admet-189	69	1	_	_	PUNCT
admet-189	70	1	_	_	PUNCT
admet-189	71	1	_	_	PUNCT
admet-189	72	1	_	_	PUNCT
admet-189	73	1	_	_	PUNCT
admet-189	74	1	_	_	PUNCT
admet-189	75	1	_	_	PUNCT
admet-189	76	1	_	_	PUNCT
admet-189	77	1	_	_	PUNCT
admet-189	78	1	_	_	PUNCT
admet-189	79	1	_	_	PUNCT
admet-189	80	1	_	_	PUNCT
admet-189	81	1	_	_	PUNCT
admet-189	82	1	_	_	PUNCT
admet-189	83	1	_	_	PUNCT
admet-189	84	1	_	_	PUNCT
admet-189	85	1	_	_	PUNCT
admet-189	86	1	_	_	PUNCT
admet-189	87	1	_	_	PUNCT
admet-189	88	1	_	_	PUNCT
admet-189	89	1	_	_	PUNCT
admet-189	90	1	_	_	PUNCT
admet-189	91	1	_	_	PUNCT
admet-189	92	1	_	_	PUNCT
admet-189	93	1	_	_	PUNCT
admet-189	94	1	_	_	PUNCT
admet-189	95	1	_	_	PUNCT
admet-189	96	1	_	_	PUNCT
admet-189	97	1	_	_	PUNCT
admet-189	98	1	_	_	PUNCT
admet-189	99	1	_	_	PUNCT
admet-189	100	1	_	_	PUNCT
admet-189	101	1	_	_	PUNCT
admet-189	102	1	_	_	PUNCT
admet-189	103	1	_	_	PUNCT
admet-189	103	2	introduction	introduction	NOUN
admet-189	103	3	parkinson	parkinson	NOUN
admet-189	103	4	’s	’s	PART
admet-189	103	5	disease	disease	NOUN
admet-189	103	6	(	(	PUNCT
admet-189	103	7	pd	pd	NOUN
admet-189	103	8	)	)	PUNCT
admet-189	103	9	,	,	PUNCT
admet-189	103	10	in	in	ADP
admet-189	103	11	the	the	DET
admet-189	103	12	present	present	ADJ
admet-189	103	13	day	day	NOUN
admet-189	103	14	,	,	PUNCT
admet-189	103	15	ranks	rank	VERB
admet-189	103	16	second	second	ADV
admet-189	103	17	after	after	ADP
admet-189	103	18	alzheimer	alzheimer	PROPN
admet-189	103	19	’s	’s	PART
admet-189	103	20	disease	disease	NOUN
admet-189	103	21	among	among	ADP
admet-189	103	22	the	the	DET
admet-189	103	23	most	most	ADV
admet-189	103	24	common	common	ADJ
admet-189	103	25	neurodegenerative	neurodegenerative	ADJ
admet-189	103	26	diseases	disease	NOUN
admet-189	103	27	and	and	CCONJ
admet-189	103	28	has	have	VERB
admet-189	103	29	characteristic	characteristic	ADJ
admet-189	103	30	motor	motor	NOUN
admet-189	103	31	and	and	CCONJ
admet-189	103	32	non	non	ADJ
admet-189	103	33	-	-	ADJ
admet-189	103	34	motor	motor	ADJ
admet-189	103	35	symptoms	symptom	NOUN
admet-189	103	36	[	[	X
admet-189	103	37	1	1	NUM
admet-189	103	38	]	]	PUNCT
admet-189	103	39	.	.	PUNCT
admet-189	104	1	globally	globally	ADV
admet-189	104	2	,	,	PUNCT
admet-189	104	3	the	the	DET
admet-189	104	4	prevalence	prevalence	NOUN
admet-189	104	5	of	of	ADP
admet-189	104	6	pd	pd	PROPN
admet-189	104	7	has	have	AUX
admet-189	104	8	been	be	AUX
admet-189	104	9	found	find	VERB
admet-189	104	10	to	to	PART
admet-189	104	11	be	be	AUX
admet-189	104	12	close	close	ADJ
admet-189	104	13	to	to	ADP
admet-189	104	14	0.3	0.3	NUM
admet-189	104	15	%	%	NOUN
admet-189	104	16	of	of	ADP
admet-189	104	17	the	the	DET
admet-189	104	18	total	total	ADJ
admet-189	104	19	population	population	NOUN
admet-189	104	20	and	and	CCONJ
admet-189	104	21	the	the	DET
admet-189	104	22	crude	crude	ADJ
admet-189	104	23	incidence	incidence	NOUN
admet-189	104	24	rate	rate	NOUN
admet-189	104	25	is	be	AUX
admet-189	104	26	4.5–19	4.5–19	NOUN
admet-189	104	27	per	per	ADP
admet-189	104	28	1,00,000	1,00,000	NUM
admet-189	104	29	population	population	NOUN
admet-189	104	30	per	per	ADP
admet-189	104	31	year	year	NOUN
admet-189	105	1	[	[	X
admet-189	105	2	2,3	2,3	NUM
admet-189	105	3	]	]	PUNCT
admet-189	105	4	.	.	PUNCT
admet-189	106	1	the	the	DET
admet-189	106	2	world	world	PROPN
admet-189	106	3	health	health	PROPN
admet-189	106	4	organization	organization	NOUN
admet-189	106	5	computed	compute	VERB
admet-189	106	6	the	the	DET
admet-189	106	7	disability	disability	NOUN
admet-189	106	8	-	-	PUNCT
admet-189	106	9	adjusted	adjust	VERB
admet-189	106	10	life	life	NOUN
admet-189	106	11	years	year	NOUN
admet-189	106	12	(	(	PUNCT
admet-189	106	13	dalys	daly	NOUN
admet-189	106	14	)	)	PUNCT
admet-189	106	15	or	or	CCONJ
admet-189	106	16	the	the	DET
admet-189	106	17	number	number	NOUN
admet-189	106	18	of	of	ADP
admet-189	106	19	years	year	NOUN
admet-189	106	20	lost	lose	VERB
admet-189	106	21	of	of	ADP
admet-189	106	22	healthy	healthy	ADJ
admet-189	106	23	life	life	NOUN
admet-189	106	24	,	,	PUNCT
admet-189	106	25	due	due	ADP
admet-189	106	26	to	to	ADP
admet-189	106	27	pd	pd	PROPN
admet-189	106	28	to	to	PART
admet-189	106	29	be	be	AUX
admet-189	106	30	1,617,000	1,617,000	NUM
admet-189	106	31	globally	globally	ADV
admet-189	106	32	in	in	ADP
admet-189	106	33	2005	2005	NUM
admet-189	106	34	and	and	CCONJ
admet-189	106	35	projected	project	VERB
admet-189	106	36	it	it	PRON
admet-189	106	37	to	to	PART
admet-189	106	38	increase	increase	VERB
admet-189	106	39	to	to	ADP
admet-189	106	40	2,015,000	2,015,000	NUM
admet-189	106	41	years	year	NOUN
admet-189	106	42	by	by	ADP
admet-189	106	43	2030	2030	NUM
admet-189	107	1	[	[	X
admet-189	107	2	3	3	NUM
admet-189	107	3	]	]	PUNCT
admet-189	107	4	.	.	PUNCT
admet-189	108	1	it	it	PRON
admet-189	108	2	would	would	AUX
admet-189	108	3	mean	mean	VERB
admet-189	108	4	that	that	SCONJ
admet-189	108	5	more	more	ADJ
admet-189	108	6	and	and	CCONJ
admet-189	108	7	more	more	ADJ
admet-189	108	8	people	people	NOUN
admet-189	108	9	would	would	AUX
admet-189	108	10	be	be	AUX
admet-189	108	11	leading	lead	VERB
admet-189	108	12	lives	life	NOUN
admet-189	108	13	with	with	ADP
admet-189	108	14	disabilities	disability	NOUN
admet-189	108	15	due	due	ADP
admet-189	108	16	to	to	ADP
admet-189	108	17	parkinson	parkinson	NOUN
admet-189	108	18	’s	’s	PART
admet-189	108	19	disease	disease	NOUN
admet-189	108	20	.	.	PUNCT
admet-189	109	1	besides	besides	SCONJ
admet-189	109	2	,	,	PUNCT
admet-189	109	3	there	there	PRON
admet-189	109	4	is	be	VERB
admet-189	109	5	a	a	DET
admet-189	109	6	huge	huge	ADJ
admet-189	109	7	cost	cost	NOUN
admet-189	109	8	that	that	PRON
admet-189	109	9	is	be	AUX
admet-189	109	10	incurred	incur	VERB
admet-189	109	11	globally	globally	ADV
admet-189	109	12	for	for	ADP
admet-189	109	13	the	the	DET
admet-189	109	14	management	management	NOUN
admet-189	109	15	of	of	ADP
admet-189	109	16	pd	pd	PROPN
admet-189	109	17	.	.	PROPN
admet-189	110	1	in	in	ADP
admet-189	110	2	developed	develop	VERB
admet-189	110	3	countries	country	NOUN
admet-189	110	4	like	like	ADP
admet-189	110	5	the	the	DET
admet-189	110	6	united	united	PROPN
admet-189	110	7	states	states	PROPN
admet-189	110	8	,	,	PUNCT
admet-189	110	9	the	the	DET
admet-189	110	10	national	national	ADJ
admet-189	110	11	economic	economic	ADJ
admet-189	110	12	burden	burden	NOUN
admet-189	110	13	of	of	ADP
admet-189	110	14	pd	pd	PROPN
admet-189	110	15	was	be	AUX
admet-189	110	16	more	more	ADJ
admet-189	110	17	than	than	ADP
admet-189	110	18	usd	usd	NOUN
admet-189	110	19	14.4	14.4	NUM
admet-189	110	20	billion	billion	NUM
admet-189	110	21	in	in	ADP
admet-189	110	22	2010	2010	NUM
admet-189	110	23	(	(	PUNCT
admet-189	110	24	approximately	approximately	ADV
admet-189	110	25	usd	usd	NOUN
admet-189	110	26	22,800	22,800	NUM
admet-189	110	27	per	per	ADP
admet-189	110	28	patient	patient	NOUN
admet-189	110	29	)	)	PUNCT
admet-189	111	1	[	[	X
admet-189	111	2	4	4	NUM
admet-189	111	3	]	]	PUNCT
admet-189	111	4	.	.	PUNCT
admet-189	112	1	in	in	ADP
admet-189	112	2	developing	develop	VERB
admet-189	112	3	countries	country	NOUN
admet-189	112	4	like	like	ADP
admet-189	112	5	india	india	PROPN
admet-189	112	6	,	,	PUNCT
admet-189	112	7	patients	patient	NOUN
admet-189	112	8	with	with	ADP
admet-189	112	9	pd	pd	PROPN
admet-189	112	10	were	be	AUX
admet-189	112	11	found	find	VERB
admet-189	112	12	to	to	PART
admet-189	112	13	spend	spend	VERB
admet-189	112	14	nearly	nearly	ADV
admet-189	112	15	16	16	NUM
admet-189	112	16	%	%	NOUN
admet-189	112	17	to	to	ADP
admet-189	112	18	41.7	41.7	NUM
admet-189	112	19	%	%	NOUN
admet-189	112	20	of	of	ADP
admet-189	112	21	the	the	DET
admet-189	112	22	average	average	ADJ
admet-189	112	23	indian	indian	ADJ
admet-189	112	24	gross	gross	ADJ
admet-189	112	25	national	national	ADJ
admet-189	112	26	income	income	NOUN
admet-189	112	27	as	as	ADP
admet-189	112	28	direct	direct	ADJ
admet-189	112	29	costs	cost	NOUN
admet-189	112	30	in	in	ADP
admet-189	112	31	the	the	DET
admet-189	112	32	treatment	treatment	NOUN
admet-189	112	33	of	of	ADP
admet-189	112	34	pd	pd	NOUN
admet-189	113	1	[	[	X
admet-189	113	2	5	5	NUM
admet-189	113	3	]	]	PUNCT
admet-189	113	4	.	.	PUNCT
admet-189	114	1	thus	thus	ADV
admet-189	114	2	,	,	PUNCT
admet-189	114	3	pd	pd	PROPN
admet-189	114	4	is	be	AUX
admet-189	114	5	a	a	DET
admet-189	114	6	universal	universal	ADJ
admet-189	114	7	disorder	disorder	NOUN
admet-189	114	8	and	and	CCONJ
admet-189	114	9	in	in	ADP
admet-189	114	10	addition	addition	NOUN
admet-189	114	11	to	to	ADP
admet-189	114	12	the	the	DET
admet-189	114	13	clinical	clinical	ADJ
admet-189	114	14	features	feature	NOUN
admet-189	114	15	,	,	PUNCT
admet-189	114	16	the	the	DET
admet-189	114	17	socioeconomic	socioeconomic	ADJ
admet-189	114	18	impact	impact	NOUN
admet-189	114	19	of	of	ADP
admet-189	114	20	pd	pd	PROPN
admet-189	114	21	is	be	AUX
admet-189	114	22	a	a	DET
admet-189	114	23	cause	cause	NOUN
admet-189	114	24	of	of	ADP
admet-189	114	25	concern	concern	NOUN
admet-189	114	26	.	.	PUNCT
admet-189	115	1	the	the	DET
admet-189	115	2	management	management	NOUN
admet-189	115	3	of	of	ADP
admet-189	115	4	pd	pd	PROPN
admet-189	115	5	has	have	VERB
admet-189	115	6	several	several	ADJ
admet-189	115	7	limitations	limitation	NOUN
admet-189	115	8	at	at	ADP
admet-189	115	9	present	present	ADJ
admet-189	115	10	.	.	PUNCT
admet-189	116	1	the	the	DET
admet-189	116	2	clinical	clinical	ADJ
admet-189	116	3	diagnosis	diagnosis	NOUN
admet-189	116	4	of	of	ADP
admet-189	116	5	pd	pd	PROPN
admet-189	116	6	originates	originate	NOUN
admet-189	116	7	to	to	ADP
admet-189	116	8	the	the	DET
admet-189	116	9	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-189	116	10	r.	r.	PROPN
admet-189	116	11	banerjee	banerjee	PROPN
admet-189	116	12	et	et	PROPN
admet-189	116	13	al	al	PROPN
admet-189	116	14	.	.	PROPN
admet-189	116	15	admet	admet	PROPN
admet-189	116	16	&	&	CCONJ
admet-189	116	17	dmpk	dmpk	PROPN
admet-189	116	18	3(3	3(3	NUM
admet-189	116	19	)	)	PUNCT
admet-189	116	20	(	(	PUNCT
admet-189	116	21	2015	2015	NUM
admet-189	116	22	)	)	PUNCT
admet-189	116	23	155	155	NUM
admet-189	116	24	-	-	SYM
admet-189	116	25	181	181	NUM
admet-189	116	26	156	156	NUM
admet-189	116	27	acclaimed	acclaim	VERB
admet-189	116	28	neurologists	neurologist	NOUN
admet-189	116	29	like	like	ADP
admet-189	116	30	parkinson	parkinson	NOUN
admet-189	116	31	and	and	CCONJ
admet-189	116	32	charcot	charcot	NOUN
admet-189	116	33	who	who	PRON
admet-189	116	34	observed	observe	VERB
admet-189	116	35	that	that	SCONJ
admet-189	116	36	the	the	DET
admet-189	116	37	presence	presence	NOUN
admet-189	116	38	of	of	ADP
admet-189	116	39	two	two	NUM
admet-189	116	40	or	or	CCONJ
admet-189	116	41	three	three	NUM
admet-189	116	42	motor	motor	NOUN
admet-189	116	43	features	feature	NOUN
admet-189	116	44	including	include	VERB
admet-189	116	45	bradykinesia	bradykinesia	PROPN
admet-189	116	46	,	,	PUNCT
admet-189	116	47	rigidity	rigidity	NOUN
admet-189	116	48	and	and	CCONJ
admet-189	116	49	tremor	tremor	NOUN
admet-189	116	50	was	be	AUX
admet-189	116	51	characteristic	characteristic	ADJ
admet-189	116	52	of	of	ADP
admet-189	116	53	parkinson	parkinson	NOUN
admet-189	116	54	’s	’s	PART
admet-189	116	55	disease	disease	NOUN
admet-189	116	56	[	[	X
admet-189	116	57	6	6	NUM
admet-189	116	58	]	]	PUNCT
admet-189	116	59	.	.	PUNCT
admet-189	117	1	two	two	NUM
admet-189	117	2	centuries	century	NOUN
admet-189	117	3	later	later	ADV
admet-189	117	4	,	,	PUNCT
admet-189	117	5	the	the	DET
admet-189	117	6	issue	issue	NOUN
admet-189	117	7	with	with	ADP
admet-189	117	8	the	the	DET
admet-189	117	9	clinical	clinical	ADJ
admet-189	117	10	diagnosis	diagnosis	NOUN
admet-189	117	11	of	of	ADP
admet-189	117	12	parkinson	parkinson	NOUN
admet-189	117	13	’s	’s	PART
admet-189	117	14	disease	disease	NOUN
admet-189	117	15	today	today	NOUN
admet-189	117	16	is	be	AUX
admet-189	117	17	that	that	SCONJ
admet-189	117	18	it	it	PRON
admet-189	117	19	fails	fail	VERB
admet-189	117	20	to	to	PART
admet-189	117	21	differentiate	differentiate	VERB
admet-189	117	22	it	it	PRON
admet-189	117	23	from	from	ADP
admet-189	117	24	the	the	DET
admet-189	117	25	many	many	ADJ
admet-189	117	26	other	other	ADJ
admet-189	117	27	forms	form	NOUN
admet-189	117	28	of	of	ADP
admet-189	117	29	parkinsonism	parkinsonism	NOUN
admet-189	117	30	[	[	X
admet-189	117	31	7	7	NUM
admet-189	117	32	]	]	PUNCT
admet-189	117	33	.	.	PUNCT
admet-189	118	1	also	also	ADV
admet-189	118	2	,	,	PUNCT
admet-189	118	3	it	it	PRON
admet-189	118	4	requires	require	VERB
admet-189	118	5	expert	expert	ADJ
admet-189	118	6	clinicians	clinician	NOUN
admet-189	118	7	for	for	ADP
admet-189	118	8	the	the	DET
admet-189	118	9	evaluation	evaluation	NOUN
admet-189	118	10	of	of	ADP
admet-189	118	11	these	these	DET
admet-189	118	12	subjective	subjective	ADJ
admet-189	118	13	features	feature	NOUN
admet-189	118	14	of	of	ADP
admet-189	118	15	the	the	DET
admet-189	118	16	disease	disease	NOUN
admet-189	118	17	.	.	PUNCT
admet-189	119	1	thus	thus	ADV
admet-189	119	2	,	,	PUNCT
admet-189	119	3	there	there	PRON
admet-189	119	4	is	be	VERB
admet-189	119	5	a	a	DET
admet-189	119	6	need	need	NOUN
admet-189	119	7	for	for	ADP
admet-189	119	8	better	well	ADJ
admet-189	119	9	biomarkers	biomarker	NOUN
admet-189	119	10	that	that	PRON
admet-189	119	11	can	can	AUX
admet-189	119	12	provide	provide	VERB
admet-189	119	13	for	for	ADP
admet-189	119	14	an	an	DET
admet-189	119	15	objective	objective	ADJ
admet-189	119	16	assessment	assessment	NOUN
admet-189	119	17	of	of	ADP
admet-189	119	18	the	the	DET
admet-189	119	19	presence	presence	NOUN
admet-189	119	20	or	or	CCONJ
admet-189	119	21	absence	absence	NOUN
admet-189	119	22	of	of	ADP
admet-189	119	23	pd	pd	PROPN
admet-189	119	24	.	.	PROPN
admet-189	119	25	beyond	beyond	ADP
admet-189	119	26	the	the	DET
admet-189	119	27	diagnosis	diagnosis	NOUN
admet-189	119	28	,	,	PUNCT
admet-189	119	29	standard	standard	ADJ
admet-189	119	30	treatment	treatment	NOUN
admet-189	119	31	modalities	modality	NOUN
admet-189	119	32	comprise	comprise	VERB
admet-189	119	33	of	of	ADP
admet-189	119	34	therapy	therapy	NOUN
admet-189	119	35	using	use	VERB
admet-189	119	36	dopamine	dopamine	NOUN
admet-189	119	37	agonists	agonist	NOUN
admet-189	119	38	and	and	CCONJ
admet-189	119	39	dopamine	dopamine	NOUN
admet-189	119	40	precursors	precursor	NOUN
admet-189	119	41	to	to	PART
admet-189	119	42	improve	improve	VERB
admet-189	119	43	clinical	clinical	ADJ
admet-189	119	44	symptoms	symptom	NOUN
admet-189	119	45	associated	associate	VERB
admet-189	119	46	with	with	ADP
admet-189	119	47	disease	disease	NOUN
admet-189	119	48	progression	progression	NOUN
admet-189	119	49	,	,	PUNCT
admet-189	119	50	patient	patient	NOUN
admet-189	119	51	’s	’s	NOUN
admet-189	119	52	care	care	NOUN
admet-189	119	53	and	and	CCONJ
admet-189	119	54	quality	quality	NOUN
admet-189	119	55	of	of	ADP
admet-189	119	56	life	life	NOUN
admet-189	119	57	.	.	PUNCT
admet-189	120	1	however	however	ADV
admet-189	120	2	,	,	PUNCT
admet-189	120	3	short	short	ADJ
admet-189	120	4	half	half	ADJ
admet-189	120	5	-	-	PUNCT
admet-189	120	6	lives	life	NOUN
admet-189	120	7	,	,	PUNCT
admet-189	120	8	treatment	treatment	NOUN
admet-189	120	9	intolerance	intolerance	NOUN
admet-189	120	10	together	together	ADV
admet-189	120	11	with	with	ADP
admet-189	120	12	side	side	ADJ
admet-189	120	13	effects	effect	NOUN
admet-189	120	14	like	like	ADP
admet-189	120	15	levodopa	levodopa	NOUN
admet-189	120	16	(	(	PUNCT
admet-189	120	17	l-3,4	l-3,4	NOUN
admet-189	120	18	-	-	ADJ
admet-189	120	19	dihydroxyphenylalanine	dihydroxyphenylalanine	ADJ
admet-189	120	20	or	or	CCONJ
admet-189	120	21	l	l	NOUN
admet-189	120	22	-	-	NOUN
admet-189	120	23	dopa	dopa	NOUN
admet-189	120	24	)	)	PUNCT
admet-189	120	25	induced	induce	VERB
admet-189	120	26	dyskinesias	dyskinesia	NOUN
admet-189	120	27	limit	limit	VERB
admet-189	120	28	the	the	DET
admet-189	120	29	long	long	ADJ
admet-189	120	30	term	term	NOUN
admet-189	120	31	treatment	treatment	NOUN
admet-189	120	32	efficacy	efficacy	NOUN
admet-189	120	33	.	.	PUNCT
admet-189	121	1	further	far	ADV
admet-189	121	2	,	,	PUNCT
admet-189	121	3	therapy	therapy	NOUN
admet-189	121	4	is	be	AUX
admet-189	121	5	limited	limit	VERB
admet-189	121	6	by	by	ADP
admet-189	121	7	the	the	DET
admet-189	121	8	presence	presence	NOUN
admet-189	121	9	of	of	ADP
admet-189	121	10	the	the	DET
admet-189	121	11	“	"	PUNCT
admet-189	121	12	blood	blood	NOUN
admet-189	121	13	-	-	PUNCT
admet-189	121	14	brain	brain	NOUN
admet-189	121	15	-	-	PUNCT
admet-189	121	16	barrier	barrier	NOUN
admet-189	121	17	”	"	PUNCT
admet-189	121	18	.	.	PUNCT
admet-189	122	1	thus	thus	ADV
admet-189	122	2	,	,	PUNCT
admet-189	122	3	in	in	ADP
admet-189	122	4	the	the	DET
admet-189	122	5	sphere	sphere	NOUN
admet-189	122	6	of	of	ADP
admet-189	122	7	treatment	treatment	NOUN
admet-189	122	8	for	for	ADP
admet-189	122	9	pd	pd	PROPN
admet-189	122	10	,	,	PUNCT
admet-189	122	11	there	there	PRON
admet-189	122	12	is	be	VERB
admet-189	122	13	a	a	DET
admet-189	122	14	need	need	NOUN
admet-189	122	15	to	to	PART
admet-189	122	16	develop	develop	VERB
admet-189	122	17	efficient	efficient	ADJ
admet-189	122	18	therapies	therapy	NOUN
admet-189	122	19	with	with	ADP
admet-189	122	20	minimal	minimal	ADJ
admet-189	122	21	side	side	NOUN
admet-189	122	22	-	-	PUNCT
admet-189	122	23	effects	effect	NOUN
admet-189	122	24	and	and	CCONJ
admet-189	122	25	increased	increase	VERB
admet-189	122	26	bioavailability	bioavailability	NOUN
admet-189	122	27	in	in	ADP
admet-189	122	28	the	the	DET
admet-189	122	29	central	central	ADJ
admet-189	122	30	nervous	nervous	ADJ
admet-189	122	31	system	system	NOUN
admet-189	122	32	.	.	PUNCT
admet-189	123	1	nanotechnology	nanotechnology	PROPN
admet-189	123	2	,	,	PUNCT
admet-189	123	3	an	an	DET
admet-189	123	4	emerging	emerge	VERB
admet-189	123	5	tool	tool	NOUN
admet-189	123	6	,	,	PUNCT
admet-189	123	7	has	have	VERB
admet-189	123	8	the	the	DET
admet-189	123	9	potential	potential	NOUN
admet-189	123	10	to	to	PART
admet-189	123	11	improve	improve	VERB
admet-189	123	12	these	these	DET
admet-189	123	13	circumstances	circumstance	NOUN
admet-189	123	14	by	by	ADP
admet-189	123	15	introducing	introduce	VERB
admet-189	123	16	novel	novel	ADJ
admet-189	123	17	carrier	carrier	NOUN
admet-189	123	18	-	-	PUNCT
admet-189	123	19	based	base	VERB
admet-189	123	20	platforms	platform	NOUN
admet-189	123	21	that	that	PRON
admet-189	123	22	will	will	AUX
admet-189	123	23	target	target	VERB
admet-189	123	24	selective	selective	ADJ
admet-189	123	25	release	release	NOUN
admet-189	123	26	of	of	ADP
admet-189	123	27	drug	drug	NOUN
admet-189	123	28	payload	payload	NOUN
admet-189	123	29	with	with	ADP
admet-189	123	30	on	on	ADP
admet-189	123	31	-	-	PUNCT
admet-189	123	32	demand	demand	NOUN
admet-189	123	33	and	and	CCONJ
admet-189	123	34	controlled	control	VERB
admet-189	123	35	release	release	NOUN
admet-189	123	36	kinetics	kinetic	NOUN
admet-189	123	37	and	and	CCONJ
admet-189	123	38	increased	increase	VERB
admet-189	123	39	reach	reach	NOUN
admet-189	123	40	via	via	ADP
admet-189	123	41	modulating	modulate	VERB
admet-189	123	42	or	or	CCONJ
admet-189	123	43	by	by	ADP
admet-189	123	44	-	-	PUNCT
admet-189	123	45	passing	pass	VERB
admet-189	123	46	the	the	DET
admet-189	123	47	blood	blood	NOUN
admet-189	123	48	-	-	PUNCT
admet-189	123	49	brain	brain	NOUN
admet-189	123	50	-	-	PUNCT
admet-189	123	51	barrier	barrier	NOUN
admet-189	123	52	.	.	PUNCT
admet-189	124	1	the	the	DET
admet-189	124	2	present	present	ADJ
admet-189	124	3	review	review	NOUN
admet-189	124	4	describes	describe	VERB
admet-189	124	5	the	the	DET
admet-189	124	6	use	use	NOUN
admet-189	124	7	of	of	ADP
admet-189	124	8	nanotechnology	nanotechnology	NOUN
admet-189	124	9	-	-	PUNCT
admet-189	124	10	based	base	VERB
admet-189	124	11	platforms	platform	NOUN
admet-189	124	12	for	for	ADP
admet-189	124	13	diagnosis	diagnosis	NOUN
admet-189	124	14	,	,	PUNCT
admet-189	124	15	drug	drug	NOUN
admet-189	124	16	delivery	delivery	NOUN
admet-189	124	17	and	and	CCONJ
admet-189	124	18	other	other	ADJ
admet-189	124	19	therapeutic	therapeutic	ADJ
admet-189	124	20	approaches	approach	NOUN
admet-189	124	21	.	.	PUNCT
admet-189	125	1	epidemiology	epidemiology	NOUN
admet-189	125	2	of	of	ADP
admet-189	125	3	parkinson	parkinson	NOUN
admet-189	125	4	’s	’s	PART
admet-189	125	5	disease	disease	NOUN
admet-189	125	6	prospective	prospective	ADJ
admet-189	125	7	and	and	CCONJ
admet-189	125	8	well	well	ADV
admet-189	125	9	-	-	PUNCT
admet-189	125	10	designed	design	VERB
admet-189	125	11	population	population	NOUN
admet-189	125	12	based	base	VERB
admet-189	125	13	studies	study	NOUN
admet-189	125	14	reported	report	VERB
admet-189	125	15	that	that	SCONJ
admet-189	125	16	prevalence	prevalence	NOUN
admet-189	125	17	and	and	CCONJ
admet-189	125	18	incidence	incidence	NOUN
admet-189	125	19	rates	rate	NOUN
admet-189	125	20	of	of	ADP
admet-189	125	21	pd	pd	PROPN
admet-189	125	22	were	be	AUX
admet-189	125	23	age	age	NOUN
admet-189	125	24	-	-	PUNCT
admet-189	125	25	specific	specific	ADJ
admet-189	125	26	i.e.	i.e.	X
admet-189	125	27	onset	onset	NOUN
admet-189	125	28	of	of	ADP
admet-189	125	29	disease	disease	NOUN
admet-189	125	30	is	be	AUX
admet-189	125	31	rare	rare	ADJ
admet-189	125	32	below	below	ADP
admet-189	125	33	50	50	NUM
admet-189	125	34	years	year	NOUN
admet-189	125	35	of	of	ADP
admet-189	125	36	age	age	NOUN
admet-189	125	37	whereas	whereas	SCONJ
admet-189	125	38	sharp	sharp	ADJ
admet-189	125	39	rise	rise	NOUN
admet-189	125	40	(	(	PUNCT
admet-189	125	41	~1	~1	ADV
admet-189	125	42	-	-	NUM
admet-189	125	43	1.5	1.5	NUM
admet-189	125	44	%	%	NOUN
admet-189	125	45	)	)	PUNCT
admet-189	125	46	is	be	AUX
admet-189	125	47	seen	see	VERB
admet-189	125	48	over	over	ADP
admet-189	125	49	60	60	NUM
admet-189	125	50	year	year	NOUN
admet-189	125	51	of	of	ADP
admet-189	125	52	age	age	NOUN
admet-189	125	53	resulting	result	VERB
admet-189	125	54	in	in	ADP
admet-189	125	55	prevalence	prevalence	NOUN
admet-189	125	56	less	less	ADJ
admet-189	125	57	than	than	ADP
admet-189	125	58	0.04	0.04	NUM
admet-189	125	59	%	%	NOUN
admet-189	125	60	below	below	ADP
admet-189	125	61	the	the	DET
admet-189	125	62	age	age	NOUN
admet-189	125	63	40	40	NUM
admet-189	125	64	years	year	NOUN
admet-189	125	65	,	,	PUNCT
admet-189	125	66	which	which	PRON
admet-189	125	67	rises	rise	VERB
admet-189	125	68	to	to	ADP
admet-189	125	69	19	19	NUM
admet-189	125	70	%	%	NOUN
admet-189	125	71	above	above	ADP
admet-189	125	72	the	the	DET
admet-189	125	73	age	age	NOUN
admet-189	125	74	of	of	ADP
admet-189	125	75	80	80	NUM
admet-189	125	76	years	year	NOUN
admet-189	126	1	[	[	X
admet-189	126	2	2,8	2,8	X
admet-189	126	3	]	]	PUNCT
admet-189	126	4	.	.	PUNCT
admet-189	127	1	the	the	DET
admet-189	127	2	prevalence	prevalence	NOUN
admet-189	127	3	of	of	ADP
admet-189	127	4	pd	pd	PROPN
admet-189	127	5	varies	varie	NOUN
admet-189	127	6	by	by	ADP
admet-189	127	7	gender	gender	NOUN
admet-189	127	8	(	(	PUNCT
admet-189	127	9	men	man	NOUN
admet-189	127	10	are	be	AUX
admet-189	127	11	more	more	ADV
admet-189	127	12	prone	prone	ADJ
admet-189	127	13	to	to	ADP
admet-189	127	14	pd	pd	PROPN
admet-189	127	15	than	than	ADP
admet-189	127	16	female	female	ADJ
admet-189	127	17	,	,	PUNCT
admet-189	127	18	possibly	possibly	ADV
admet-189	127	19	due	due	ADP
admet-189	127	20	to	to	ADP
admet-189	127	21	the	the	DET
admet-189	127	22	neuroprotective	neuroprotective	ADJ
admet-189	127	23	effect	effect	NOUN
admet-189	127	24	of	of	ADP
admet-189	127	25	estrogens	estrogen	NOUN
admet-189	127	26	)	)	PUNCT
admet-189	127	27	,	,	PUNCT
admet-189	127	28	race/	race/	NUM
admet-189	127	29	ethnicity	ethnicity	NOUN
admet-189	127	30	(	(	PUNCT
admet-189	127	31	incidence	incidence	NOUN
admet-189	127	32	rates	rate	NOUN
admet-189	127	33	were	be	AUX
admet-189	127	34	found	find	VERB
admet-189	127	35	to	to	PART
admet-189	127	36	be	be	AUX
admet-189	127	37	highest	high	ADJ
admet-189	127	38	among	among	ADP
admet-189	127	39	hispanics	hispanic	NOUN
admet-189	127	40	>	>	SYM
admet-189	127	41	non	non	ADJ
admet-189	127	42	-	-	ADJ
admet-189	127	43	hispanic	hispanic	ADJ
admet-189	127	44	>	>	ADJ
admet-189	127	45	whites	white	NOUN
admet-189	127	46	>	>	X
admet-189	127	47	asian	asian	PROPN
admet-189	127	48	>	>	X
admet-189	127	49	blacks	black	NOUN
admet-189	127	50	)	)	PUNCT
admet-189	128	1	[	[	X
admet-189	128	2	9	9	NUM
admet-189	128	3	]	]	PUNCT
admet-189	128	4	.	.	PUNCT
admet-189	129	1	differences	difference	NOUN
admet-189	129	2	in	in	ADP
admet-189	129	3	environmental	environmental	ADJ
admet-189	129	4	factors	factor	NOUN
admet-189	129	5	like	like	ADP
admet-189	129	6	occupational	occupational	ADJ
admet-189	129	7	exposures	exposure	NOUN
admet-189	129	8	(	(	PUNCT
admet-189	129	9	pesticides	pesticide	NOUN
admet-189	129	10	,	,	PUNCT
admet-189	129	11	heavy	heavy	ADJ
admet-189	129	12	metals	metal	NOUN
admet-189	129	13	)	)	PUNCT
admet-189	129	14	and	and	CCONJ
admet-189	129	15	cigarette	cigarette	NOUN
admet-189	129	16	smoking	smoking	NOUN
admet-189	129	17	;	;	PUNCT
admet-189	129	18	dietary	dietary	ADJ
admet-189	129	19	factors	factor	NOUN
admet-189	129	20	(	(	PUNCT
admet-189	129	21	anti	anti	ADJ
admet-189	129	22	-	-	NOUN
admet-189	129	23	oxidants	oxidant	NOUN
admet-189	129	24	like	like	ADP
admet-189	129	25	vitamin	vitamin	NOUN
admet-189	129	26	e	e	NOUN
admet-189	129	27	,	,	PUNCT
admet-189	129	28	fatty	fatty	ADJ
admet-189	129	29	acids	acid	NOUN
admet-189	129	30	mainly	mainly	ADV
admet-189	129	31	unsaturated	unsaturate	VERB
admet-189	129	32	fatty	fatty	NOUN
admet-189	129	33	acids	acid	NOUN
admet-189	129	34	,	,	PUNCT
admet-189	129	35	dietary	dietary	ADJ
admet-189	129	36	iron	iron	NOUN
admet-189	129	37	etc	etc	X
admet-189	129	38	.	.	PUNCT
admet-189	129	39	)	)	PUNCT
admet-189	129	40	,	,	PUNCT
admet-189	129	41	genetic	genetic	ADJ
admet-189	129	42	factors	factor	NOUN
admet-189	129	43	like	like	ADP
admet-189	129	44	α	α	NOUN
admet-189	129	45	-	-	PUNCT
admet-189	129	46	synuclein	synuclein	NOUN
admet-189	129	47	(	(	PUNCT
admet-189	129	48	park1	park1	NOUN
admet-189	129	49	)	)	PUNCT
admet-189	129	50	,	,	PUNCT
admet-189	129	51	parkin	parkin	X
admet-189	129	52	(	(	PUNCT
admet-189	129	53	park2	park2	NOUN
admet-189	129	54	)	)	PUNCT
admet-189	129	55	,	,	PUNCT
admet-189	129	56	genes	gene	NOUN
admet-189	129	57	involved	involve	VERB
admet-189	129	58	in	in	ADP
admet-189	129	59	dopamine	dopamine	NOUN
admet-189	129	60	metabolism	metabolism	NOUN
admet-189	129	61	,	,	PUNCT
admet-189	129	62	homocysteine	homocysteine	ADJ
admet-189	129	63	metabolism	metabolism	NOUN
admet-189	129	64	and	and	CCONJ
admet-189	129	65	polymorphism	polymorphism	NOUN
admet-189	129	66	in	in	ADP
admet-189	129	67	mitochondrial	mitochondrial	ADJ
admet-189	129	68	dna	dna	NOUN
admet-189	129	69	etc	etc	X
admet-189	129	70	.	.	X
admet-189	129	71	are	be	AUX
admet-189	129	72	responsible	responsible	ADJ
admet-189	129	73	for	for	ADP
admet-189	129	74	pd	pd	PROPN
admet-189	129	75	progression	progression	NOUN
admet-189	129	76	with	with	ADP
admet-189	129	77	variations	variation	NOUN
admet-189	129	78	in	in	ADP
admet-189	129	79	its	its	PRON
admet-189	129	80	prevalence	prevalence	NOUN
admet-189	129	81	and	and	CCONJ
admet-189	129	82	incidence	incidence	NOUN
admet-189	129	83	[	[	X
admet-189	129	84	9	9	NUM
admet-189	129	85	]	]	PUNCT
admet-189	129	86	.	.	PUNCT
admet-189	130	1	etiology	etiology	NOUN
admet-189	130	2	and	and	CCONJ
admet-189	130	3	pathophysiological	pathophysiological	ADJ
admet-189	130	4	hallmarks	hallmark	NOUN
admet-189	130	5	of	of	ADP
admet-189	130	6	parkinson	parkinson	NOUN
admet-189	130	7	’s	’s	PART
admet-189	130	8	disease	disease	NOUN
admet-189	130	9	for	for	ADP
admet-189	130	10	designing	design	VERB
admet-189	130	11	of	of	ADP
admet-189	130	12	successful	successful	ADJ
admet-189	130	13	diagnostic	diagnostic	ADJ
admet-189	130	14	and	and	CCONJ
admet-189	130	15	therapeutic	therapeutic	ADJ
admet-189	130	16	strategies	strategy	NOUN
admet-189	130	17	against	against	ADP
admet-189	130	18	pd	pd	PROPN
admet-189	130	19	it	it	PRON
admet-189	130	20	is	be	AUX
admet-189	130	21	important	important	ADJ
admet-189	130	22	to	to	PART
admet-189	130	23	understand	understand	VERB
admet-189	130	24	the	the	DET
admet-189	130	25	etiology	etiology	NOUN
admet-189	130	26	and	and	CCONJ
admet-189	130	27	pathophysiology	pathophysiology	NOUN
admet-189	130	28	behind	behind	ADP
admet-189	130	29	development	development	NOUN
admet-189	130	30	and	and	CCONJ
admet-189	130	31	progression	progression	NOUN
admet-189	130	32	of	of	ADP
admet-189	130	33	pd	pd	PROPN
admet-189	130	34	.	.	PROPN
admet-189	130	35	pd	pd	PROPN
admet-189	130	36	is	be	AUX
admet-189	130	37	a	a	DET
admet-189	130	38	chronic	chronic	NOUN
admet-189	130	39	,	,	PUNCT
admet-189	130	40	progressive	progressive	ADJ
admet-189	130	41	neurodegenerative	neurodegenerative	ADJ
admet-189	130	42	disease	disease	NOUN
admet-189	130	43	characterized	characterize	VERB
admet-189	130	44	by	by	ADP
admet-189	130	45	impairment	impairment	NOUN
admet-189	130	46	in	in	ADP
admet-189	130	47	motor	motor	NOUN
admet-189	130	48	and	and	CCONJ
admet-189	130	49	non	non	ADJ
admet-189	130	50	-	-	ADJ
admet-189	130	51	motor	motor	ADJ
admet-189	130	52	activities	activity	NOUN
admet-189	130	53	with	with	ADP
admet-189	130	54	symptoms	symptom	NOUN
admet-189	130	55	like	like	ADP
admet-189	130	56	akinesia	akinesia	NOUN
admet-189	130	57	,	,	PUNCT
admet-189	130	58	tremor	tremor	NOUN
admet-189	130	59	,	,	PUNCT
admet-189	130	60	muscle	muscle	NOUN
admet-189	130	61	rigidity	rigidity	NOUN
admet-189	130	62	,	,	PUNCT
admet-189	130	63	postural	postural	ADJ
admet-189	130	64	instability	instability	NOUN
admet-189	130	65	,	,	PUNCT
admet-189	130	66	freezing	freezing	NOUN
admet-189	130	67	of	of	ADP
admet-189	130	68	gait	gait	NOUN
admet-189	130	69	and	and	CCONJ
admet-189	130	70	depression	depression	NOUN
admet-189	130	71	,	,	PUNCT
admet-189	130	72	delirium	delirium	NOUN
admet-189	130	73	,	,	PUNCT
admet-189	130	74	dementia	dementia	NOUN
admet-189	130	75	,	,	PUNCT
admet-189	130	76	sleep	sleep	NOUN
admet-189	130	77	disorders	disorder	NOUN
admet-189	130	78	,	,	PUNCT
admet-189	130	79	autonomic	autonomic	ADJ
admet-189	130	80	symptoms	symptom	NOUN
admet-189	130	81	(	(	PUNCT
admet-189	130	82	bradycardia	bradycardia	NOUN
admet-189	130	83	,	,	PUNCT
admet-189	130	84	sialorrhea	sialorrhea	ADJ
admet-189	130	85	,	,	PUNCT
admet-189	130	86	sexual	sexual	ADJ
admet-189	130	87	dysfunctions	dysfunction	NOUN
admet-189	130	88	and	and	CCONJ
admet-189	130	89	dry	dry	ADJ
admet-189	130	90	eyes	eye	NOUN
admet-189	130	91	syndromes	syndrome	NOUN
admet-189	130	92	etc	etc	X
admet-189	130	93	.	.	PUNCT
admet-189	130	94	)	)	PUNCT
admet-189	131	1	and	and	CCONJ
admet-189	131	2	other	other	ADJ
admet-189	131	3	symptoms	symptom	NOUN
admet-189	131	4	like	like	ADP
admet-189	131	5	olfactory	olfactory	ADJ
admet-189	131	6	disturbances	disturbance	NOUN
admet-189	131	7	,	,	PUNCT
admet-189	131	8	fatigue	fatigue	NOUN
admet-189	131	9	,	,	PUNCT
admet-189	131	10	weight	weight	NOUN
admet-189	131	11	changes	change	NOUN
admet-189	131	12	etc	etc	X
admet-189	131	13	.	.	PUNCT
admet-189	132	1	the	the	DET
admet-189	132	2	classical	classical	ADJ
admet-189	132	3	pathophysiological	pathophysiological	ADJ
admet-189	132	4	hallmark	hallmark	NOUN
admet-189	132	5	of	of	ADP
admet-189	132	6	pd	pd	PROPN
admet-189	132	7	is	be	AUX
admet-189	132	8	the	the	DET
admet-189	132	9	presence	presence	NOUN
admet-189	132	10	of	of	ADP
admet-189	132	11	lewy	lewy	PROPN
admet-189	132	12	bodies	body	NOUN
admet-189	132	13	in	in	ADP
admet-189	132	14	the	the	DET
admet-189	132	15	dopaminergic	dopaminergic	ADJ
admet-189	132	16	neurons	neuron	NOUN
admet-189	132	17	that	that	PRON
admet-189	132	18	are	be	AUX
admet-189	132	19	left	leave	VERB
admet-189	132	20	behind	behind	ADV
admet-189	132	21	after	after	ADP
admet-189	132	22	degeneration	degeneration	NOUN
admet-189	132	23	of	of	ADP
admet-189	132	24	these	these	DET
admet-189	132	25	neurons	neuron	NOUN
admet-189	132	26	in	in	ADP
admet-189	132	27	substantia	substantia	NOUN
admet-189	132	28	nigra	nigra	PROPN
admet-189	132	29	pars	par	NOUN
admet-189	132	30	compacta	compacta	NOUN
admet-189	132	31	.	.	PUNCT
admet-189	133	1	this	this	DET
admet-189	133	2	results	result	VERB
admet-189	133	3	in	in	ADP
admet-189	133	4	dopamine	dopamine	NOUN
admet-189	133	5	depletion	depletion	NOUN
admet-189	133	6	in	in	ADP
admet-189	133	7	the	the	DET
admet-189	133	8	striatum	striatum	NOUN
admet-189	133	9	and	and	CCONJ
admet-189	133	10	basal	basal	ADJ
admet-189	133	11	ganglia	ganglia	NOUN
admet-189	133	12	nuclei	nucleus	NOUN
admet-189	133	13	due	due	ADP
admet-189	133	14	to	to	ADP
admet-189	133	15	innervations	innervation	NOUN
admet-189	133	16	of	of	ADP
admet-189	133	17	dopamine	dopamine	NOUN
admet-189	133	18	neurons	neuron	NOUN
admet-189	133	19	in	in	ADP
admet-189	133	20	two	two	NUM
admet-189	133	21	segments	segment	NOUN
admet-189	133	22	of	of	ADP
admet-189	133	23	globus	globus	NOUN
admet-189	133	24	pallidus	pallidus	X
admet-189	133	25	i.e.	i.e.	X
admet-189	133	26	external	external	ADJ
admet-189	133	27	and	and	CCONJ
admet-189	133	28	internal	internal	ADJ
admet-189	133	29	parts	part	NOUN
admet-189	133	30	of	of	ADP
admet-189	133	31	basal	basal	ADJ
admet-189	133	32	ganglia	ganglia	NOUN
admet-189	133	33	nuclei	nucleus	NOUN
admet-189	133	34	and	and	CCONJ
admet-189	133	35	also	also	ADV
admet-189	133	36	auxiliary	auxiliary	ADJ
admet-189	133	37	to	to	ADP
admet-189	133	38	subthalamic	subthalamic	ADJ
admet-189	133	39	nucleus	nucleus	NOUN
admet-189	133	40	and	and	CCONJ
admet-189	133	41	thalamus	thalamus	VERB
admet-189	133	42	[	[	X
admet-189	133	43	10	10	NUM
admet-189	133	44	]	]	PUNCT
admet-189	133	45	.	.	PUNCT
admet-189	134	1	the	the	DET
admet-189	134	2	etiological	etiological	ADJ
admet-189	134	3	factors	factor	NOUN
admet-189	134	4	include	include	VERB
admet-189	134	5	toxins	toxin	NOUN
admet-189	134	6	mainly	mainly	ADV
admet-189	134	7	mptp	mptp	NOUN
admet-189	134	8	(	(	PUNCT
admet-189	134	9	1methyl-4	1methyl-4	NUM
admet-189	134	10	-	-	PUNCT
admet-189	134	11	phenyl-1,2,3,6	phenyl-1,2,3,6	NOUN
admet-189	134	12	-	-	PUNCT
admet-189	134	13	tetrahydropyridine	tetrahydropyridine	ADJ
admet-189	134	14	)	)	PUNCT
admet-189	134	15	which	which	PRON
admet-189	134	16	produced	produce	VERB
admet-189	134	17	mpp+	mpp+	PROPN
admet-189	134	18	(	(	PUNCT
admet-189	134	19	1	1	NUM
admet-189	134	20	-	-	PUNCT
admet-189	134	21	methyl-4	methyl-4	NOUN
admet-189	134	22	-	-	PUNCT
admet-189	134	23	phenylpyridinium	phenylpyridinium	NOUN
admet-189	134	24	)	)	PUNCT
admet-189	134	25	,	,	PUNCT
admet-189	134	26	a	a	DET
admet-189	134	27	admet	admet	PROPN
admet-189	134	28	&	&	CCONJ
admet-189	134	29	dmpk	dmpk	PROPN
admet-189	134	30	3(3	3(3	NUM
admet-189	134	31	)	)	PUNCT
admet-189	134	32	(	(	PUNCT
admet-189	134	33	2015	2015	NUM
admet-189	134	34	)	)	PUNCT
admet-189	134	35	155	155	NUM
admet-189	134	36	-	-	SYM
admet-189	134	37	181	181	NUM
admet-189	134	38	nanotechnology	nanotechnology	NOUN
admet-189	134	39	platforms	platform	NOUN
admet-189	134	40	in	in	ADP
admet-189	134	41	parkinson	parkinson	NOUN
admet-189	134	42	’s	’s	PART
admet-189	134	43	disease	disease	NOUN
admet-189	134	44	doi	doi	NOUN
admet-189	134	45	:	:	PUNCT
admet-189	134	46	10.5599	10.5599	NUM
admet-189	134	47	/	/	SYM
admet-189	134	48	admet.3.3.189	admet.3.3.189	ADP
admet-189	134	49	157	157	NUM
admet-189	134	50	neuro	neuro	ADJ
admet-189	134	51	-	-	PUNCT
admet-189	134	52	toxic	toxic	ADJ
admet-189	134	53	precursor	precursor	NOUN
admet-189	134	54	by	by	ADP
admet-189	134	55	monoamine	monoamine	ADJ
admet-189	134	56	oxidase	oxidase	PROPN
admet-189	134	57	-	-	PUNCT
admet-189	134	58	b	b	PROPN
admet-189	134	59	(	(	PUNCT
admet-189	134	60	mao	mao	PROPN
admet-189	134	61	-	-	PUNCT
admet-189	134	62	b	b	NOUN
admet-189	134	63	)	)	PUNCT
admet-189	134	64	that	that	PRON
admet-189	134	65	further	far	ADV
admet-189	134	66	interferes	interfere	VERB
admet-189	134	67	in	in	ADP
admet-189	134	68	mitochondrial	mitochondrial	ADJ
admet-189	134	69	metabolism	metabolism	NOUN
admet-189	134	70	leading	lead	VERB
admet-189	134	71	to	to	ADP
admet-189	134	72	free	free	ADJ
admet-189	134	73	radical	radical	ADJ
admet-189	134	74	generation	generation	NOUN
admet-189	134	75	and	and	CCONJ
admet-189	134	76	subsequently	subsequently	ADV
admet-189	134	77	causes	cause	VERB
admet-189	134	78	dopaminergic	dopaminergic	ADJ
admet-189	134	79	neuron	neuron	NOUN
admet-189	134	80	degeneration	degeneration	NOUN
admet-189	134	81	in	in	ADP
admet-189	134	82	the	the	DET
admet-189	134	83	substantia	substantia	NOUN
admet-189	134	84	nigra	nigra	NOUN
admet-189	135	1	[	[	X
admet-189	135	2	11	11	NUM
admet-189	135	3	]	]	PUNCT
admet-189	135	4	.	.	PUNCT
admet-189	136	1	various	various	ADJ
admet-189	136	2	other	other	ADJ
admet-189	136	3	toxins	toxin	NOUN
admet-189	136	4	include	include	VERB
admet-189	136	5	taclo	taclo	VERB
admet-189	136	6	(	(	PUNCT
admet-189	136	7	formed	form	VERB
admet-189	136	8	from	from	ADP
admet-189	136	9	interaction	interaction	NOUN
admet-189	136	10	between	between	ADP
admet-189	136	11	sedative	sedative	ADJ
admet-189	136	12	agents	agent	NOUN
admet-189	136	13	like	like	ADP
admet-189	136	14	chloral	chloral	ADJ
admet-189	136	15	or	or	CCONJ
admet-189	136	16	organic	organic	ADJ
admet-189	136	17	solvents	solvent	NOUN
admet-189	136	18	like	like	ADP
admet-189	136	19	trichloroethylene	trichloroethylene	NOUN
admet-189	136	20	with	with	ADP
admet-189	136	21	endogenous	endogenous	ADJ
admet-189	136	22	tryptamine	tryptamine	NOUN
admet-189	136	23	)	)	PUNCT
admet-189	136	24	were	be	AUX
admet-189	136	25	also	also	ADV
admet-189	136	26	reported	report	VERB
admet-189	136	27	to	to	PART
admet-189	136	28	be	be	AUX
admet-189	136	29	toxic	toxic	ADJ
admet-189	136	30	to	to	ADP
admet-189	136	31	dopaminergic	dopaminergic	ADJ
admet-189	136	32	neurons	neuron	NOUN
admet-189	136	33	[	[	X
admet-189	136	34	12	12	NUM
admet-189	136	35	]	]	PUNCT
admet-189	136	36	.	.	PUNCT
admet-189	137	1	other	other	ADJ
admet-189	137	2	pathological	pathological	ADJ
admet-189	137	3	hallmarks	hallmark	NOUN
admet-189	137	4	includes	include	VERB
admet-189	137	5	degeneration	degeneration	NOUN
admet-189	137	6	of	of	ADP
admet-189	137	7	non	non	ADJ
admet-189	137	8	-	-	ADJ
admet-189	137	9	dopaminergic	dopaminergic	ADJ
admet-189	137	10	neurons	neuron	NOUN
admet-189	137	11	leading	lead	VERB
admet-189	137	12	to	to	ADP
admet-189	137	13	depletion	depletion	NOUN
admet-189	137	14	of	of	ADP
admet-189	137	15	nor	nor	CCONJ
admet-189	137	16	-	-	PUNCT
admet-189	137	17	adrenaline	adrenaline	NOUN
admet-189	137	18	,	,	PUNCT
admet-189	137	19	serotonin	serotonin	VERB
admet-189	137	20	(	(	PUNCT
admet-189	137	21	depletion	depletion	NOUN
admet-189	137	22	or	or	CCONJ
admet-189	137	23	hyperactivity	hyperactivity	NOUN
admet-189	137	24	of	of	ADP
admet-189	137	25	5	5	NUM
admet-189	137	26	-	-	PUNCT
admet-189	137	27	hydroxy	hydroxy	ADJ
admet-189	137	28	tryptamine	tryptamine	NOUN
admet-189	137	29	in	in	ADP
admet-189	137	30	the	the	DET
admet-189	137	31	brain	brain	NOUN
admet-189	137	32	giving	give	VERB
admet-189	137	33	rise	rise	NOUN
admet-189	137	34	to	to	ADP
admet-189	137	35	symptoms	symptom	NOUN
admet-189	137	36	such	such	ADJ
admet-189	137	37	as	as	ADP
admet-189	137	38	depression	depression	NOUN
admet-189	137	39	and	and	CCONJ
admet-189	137	40	hallucinations	hallucination	NOUN
admet-189	137	41	)	)	PUNCT
admet-189	137	42	,	,	PUNCT
admet-189	137	43	glutamic	glutamic	ADJ
admet-189	137	44	acid	acid	NOUN
admet-189	137	45	,	,	PUNCT
admet-189	137	46	gamma	gamma	NOUN
admet-189	137	47	-	-	PUNCT
admet-189	137	48	amino	amino	NOUN
admet-189	137	49	butyric	butyric	ADJ
admet-189	137	50	acid	acid	NOUN
admet-189	137	51	(	(	PUNCT
admet-189	137	52	gaba	gaba	PROPN
admet-189	137	53	)	)	PUNCT
admet-189	137	54	,	,	PUNCT
admet-189	137	55	neuropeptides	neuropeptide	NOUN
admet-189	137	56	like	like	ADP
admet-189	137	57	endorphins	endorphin	NOUN
admet-189	137	58	(	(	PUNCT
admet-189	137	59	enkephalins	enkephalin	NOUN
admet-189	137	60	and	and	CCONJ
admet-189	137	61	dynorphins	dynorphin	NOUN
admet-189	137	62	)	)	PUNCT
admet-189	137	63	and	and	CCONJ
admet-189	137	64	acetylcholine	acetylcholine	NOUN
admet-189	137	65	etc	etc	X
admet-189	137	66	.	.	PUNCT
admet-189	138	1	[	[	X
admet-189	138	2	13	13	NUM
admet-189	138	3	-	-	SYM
admet-189	138	4	16	16	NUM
admet-189	138	5	]	]	PUNCT
admet-189	138	6	.	.	PUNCT
admet-189	139	1	the	the	DET
admet-189	139	2	pathophysiology	pathophysiology	NOUN
admet-189	139	3	of	of	ADP
admet-189	139	4	pd	pd	PROPN
admet-189	139	5	remains	remain	VERB
admet-189	139	6	ambiguous	ambiguous	ADJ
admet-189	139	7	,	,	PUNCT
admet-189	139	8	and	and	CCONJ
admet-189	139	9	is	be	AUX
admet-189	139	10	under	under	ADP
admet-189	139	11	continuous	continuous	ADJ
admet-189	139	12	active	active	ADJ
admet-189	139	13	investigations	investigation	NOUN
admet-189	139	14	till	till	SCONJ
admet-189	139	15	date	date	NOUN
admet-189	139	16	.	.	PUNCT
admet-189	140	1	olanow	olanow	PROPN
admet-189	140	2	and	and	CCONJ
admet-189	140	3	tatton	tatton	PROPN
admet-189	140	4	(	(	PUNCT
admet-189	140	5	1999	1999	NUM
admet-189	140	6	)	)	PUNCT
admet-189	140	7	have	have	AUX
admet-189	140	8	reported	report	VERB
admet-189	140	9	that	that	SCONJ
admet-189	140	10	potential	potential	ADJ
admet-189	140	11	genes	gene	NOUN
admet-189	140	12	like	like	ADP
admet-189	140	13	glutathione	glutathione	NOUN
admet-189	140	14	peroxidase	peroxidase	NOUN
admet-189	140	15	,	,	PUNCT
admet-189	140	16	superoxide	superoxide	NOUN
admet-189	140	17	dismutase-1	dismutase-1	PROPN
admet-189	140	18	,	,	PUNCT
admet-189	140	19	2	2	NUM
admet-189	140	20	and	and	CCONJ
admet-189	140	21	dopamine	dopamine	NOUN
admet-189	140	22	receptors	receptor	NOUN
admet-189	140	23	(	(	PUNCT
admet-189	140	24	d2	d2	NOUN
admet-189	140	25	-	-	PUNCT
admet-189	140	26	4	4	NUM
admet-189	140	27	)	)	PUNCT
admet-189	140	28	etc	etc	X
admet-189	140	29	.	.	X
admet-189	140	30	contribute	contribute	VERB
admet-189	140	31	to	to	ADP
admet-189	140	32	5	5	NUM
admet-189	140	33	-	-	SYM
admet-189	140	34	10	10	NUM
admet-189	140	35	%	%	NOUN
admet-189	140	36	familial	familial	ADJ
admet-189	140	37	pd	pd	NOUN
admet-189	140	38	with	with	ADP
admet-189	140	39	autosomal	autosomal	ADJ
admet-189	140	40	dominant	dominant	ADJ
admet-189	140	41	or	or	CCONJ
admet-189	140	42	recessive	recessive	ADJ
admet-189	140	43	inheritance	inheritance	NOUN
admet-189	141	1	[	[	X
admet-189	141	2	17	17	NUM
admet-189	141	3	]	]	PUNCT
admet-189	141	4	.	.	PUNCT
admet-189	142	1	the	the	DET
admet-189	142	2	pathogenesis	pathogenesis	NOUN
admet-189	142	3	of	of	ADP
admet-189	142	4	pd	pd	PROPN
admet-189	142	5	includes	include	VERB
admet-189	142	6	oxidative	oxidative	ADJ
admet-189	142	7	stress	stress	NOUN
admet-189	142	8	in	in	ADP
admet-189	142	9	substantia	substantia	NOUN
admet-189	142	10	nigra	nigra	VERB
admet-189	142	11	through	through	ADP
admet-189	142	12	production	production	NOUN
admet-189	142	13	of	of	ADP
admet-189	142	14	reactive	reactive	ADJ
admet-189	142	15	oxygen	oxygen	NOUN
admet-189	142	16	species	specie	NOUN
admet-189	142	17	(	(	PUNCT
admet-189	142	18	ros	ros	PROPN
admet-189	142	19	)	)	PUNCT
admet-189	142	20	and	and	CCONJ
admet-189	142	21	hydrogen	hydrogen	NOUN
admet-189	142	22	peroxide	peroxide	NOUN
admet-189	142	23	by	by	ADP
admet-189	142	24	extensive	extensive	ADJ
admet-189	142	25	oxidative	oxidative	ADJ
admet-189	142	26	metabolism	metabolism	NOUN
admet-189	142	27	of	of	ADP
admet-189	142	28	dopamine	dopamine	NOUN
admet-189	142	29	.	.	PUNCT
admet-189	143	1	collectively	collectively	ADV
admet-189	143	2	,	,	PUNCT
admet-189	143	3	the	the	DET
admet-189	143	4	increased	increase	VERB
admet-189	143	5	turnover	turnover	NOUN
admet-189	143	6	of	of	ADP
admet-189	143	7	dopamine	dopamine	NOUN
admet-189	143	8	,	,	PUNCT
admet-189	143	9	decreased	decrease	VERB
admet-189	143	10	glutathione	glutathione	NOUN
admet-189	143	11	levels	level	NOUN
admet-189	143	12	and	and	CCONJ
admet-189	143	13	presence	presence	NOUN
admet-189	143	14	of	of	ADP
admet-189	143	15	reactive	reactive	ADJ
admet-189	143	16	iron	iron	NOUN
admet-189	143	17	promotes	promote	VERB
admet-189	143	18	generation	generation	NOUN
admet-189	143	19	of	of	ADP
admet-189	143	20	free	free	ADJ
admet-189	143	21	radicals	radical	NOUN
admet-189	143	22	which	which	PRON
admet-189	143	23	may	may	AUX
admet-189	143	24	be	be	AUX
admet-189	143	25	responsible	responsible	ADJ
admet-189	143	26	of	of	ADP
admet-189	143	27	disease	disease	NOUN
admet-189	143	28	development	development	NOUN
admet-189	143	29	and	and	CCONJ
admet-189	143	30	progression	progression	NOUN
admet-189	143	31	[	[	X
admet-189	143	32	17	17	NUM
admet-189	143	33	]	]	PUNCT
admet-189	143	34	.	.	PUNCT
admet-189	144	1	previous	previous	ADJ
admet-189	144	2	studies	study	NOUN
admet-189	144	3	reported	report	VERB
admet-189	144	4	oxidative	oxidative	ADJ
admet-189	144	5	damage	damage	NOUN
admet-189	144	6	to	to	ADP
admet-189	144	7	the	the	DET
admet-189	144	8	dna	dna	PROPN
admet-189	144	9	{	{	PUNCT
admet-189	144	10	elevated	elevated	ADJ
admet-189	144	11	levels	level	NOUN
admet-189	144	12	of	of	ADP
admet-189	144	13	8	8	NUM
admet-189	144	14	-	-	PUNCT
admet-189	144	15	hydroxyguanine	hydroxyguanine	NOUN
admet-189	144	16	(	(	PUNCT
admet-189	144	17	8	8	NUM
admet-189	144	18	-	-	PUNCT
admet-189	144	19	ohg	ohg	NOUN
admet-189	144	20	)	)	PUNCT
admet-189	144	21	}	}	PUNCT
admet-189	144	22	,	,	PUNCT
admet-189	144	23	in	in	ADP
admet-189	144	24	substantia	substantia	NOUN
admet-189	144	25	nigra	nigra	NOUN
admet-189	144	26	of	of	ADP
admet-189	144	27	pd	pd	PROPN
admet-189	144	28	patients	patient	NOUN
admet-189	144	29	due	due	ADP
admet-189	144	30	to	to	ADP
admet-189	144	31	free	free	ADJ
admet-189	144	32	species	specie	NOUN
admet-189	144	33	like	like	ADP
admet-189	144	34	peroxynitrite	peroxynitrite	NOUN
admet-189	144	35	,	,	PUNCT
admet-189	144	36	hydroxyl	hydroxyl	NOUN
admet-189	144	37	radicals	radical	NOUN
admet-189	144	38	etc	etc	X
admet-189	144	39	.	.	PUNCT
admet-189	145	1	[	[	X
admet-189	145	2	18	18	NUM
admet-189	145	3	]	]	PUNCT
admet-189	145	4	.	.	PUNCT
admet-189	146	1	in	in	ADP
admet-189	146	2	1990	1990	NUM
admet-189	146	3	,	,	PUNCT
admet-189	146	4	schapira	schapira	NOUN
admet-189	146	5	and	and	CCONJ
admet-189	146	6	co	co	NOUN
admet-189	146	7	-	-	NOUN
admet-189	146	8	workers	worker	NOUN
admet-189	146	9	reported	report	VERB
admet-189	146	10	the	the	DET
admet-189	146	11	role	role	NOUN
admet-189	146	12	of	of	ADP
admet-189	146	13	increased	increase	VERB
admet-189	146	14	mitochondrial	mitochondrial	ADJ
admet-189	146	15	dysfunction	dysfunction	NOUN
admet-189	146	16	in	in	ADP
admet-189	146	17	pd	pd	PROPN
admet-189	146	18	patients	patient	NOUN
admet-189	146	19	and	and	CCONJ
admet-189	146	20	association	association	NOUN
admet-189	146	21	with	with	ADP
admet-189	146	22	defects	defect	NOUN
admet-189	146	23	in	in	ADP
admet-189	146	24	mitochondrial	mitochondrial	ADJ
admet-189	146	25	complex	complex	NOUN
admet-189	146	26	-	-	PUNCT
admet-189	146	27	i	i	PRON
admet-189	146	28	of	of	ADP
admet-189	146	29	the	the	DET
admet-189	146	30	respiratory	respiratory	ADJ
admet-189	146	31	chain	chain	NOUN
admet-189	146	32	leading	lead	VERB
admet-189	146	33	to	to	ADP
admet-189	146	34	nigrostriatal	nigrostriatal	ADJ
admet-189	146	35	neuronal	neuronal	ADJ
admet-189	146	36	degeneration	degeneration	NOUN
admet-189	146	37	through	through	ADP
admet-189	146	38	depletion	depletion	NOUN
admet-189	146	39	of	of	ADP
admet-189	146	40	atp	atp	NOUN
admet-189	146	41	synthesis	synthesis	NOUN
admet-189	146	42	[	[	X
admet-189	146	43	19	19	NUM
admet-189	146	44	]	]	PUNCT
admet-189	146	45	.	.	PUNCT
admet-189	147	1	several	several	ADJ
admet-189	147	2	studies	study	NOUN
admet-189	147	3	demonstrated	demonstrate	VERB
admet-189	147	4	that	that	SCONJ
admet-189	147	5	different	different	ADJ
admet-189	147	6	genes	gene	NOUN
admet-189	147	7	like	like	ADP
admet-189	147	8	α	α	NOUN
admet-189	147	9	-	-	PUNCT
admet-189	147	10	synuclein	synuclein	NOUN
admet-189	147	11	,	,	PUNCT
admet-189	147	12	parkin	parkin	ADJ
admet-189	147	13	and	and	CCONJ
admet-189	147	14	uch	uch	ADJ
admet-189	147	15	-	-	PUNCT
admet-189	147	16	l1	l1	PROPN
admet-189	147	17	(	(	PUNCT
admet-189	147	18	gene	gene	NOUN
admet-189	147	19	encoding	encode	VERB
admet-189	147	20	ubiquitin	ubiquitin	ADJ
admet-189	147	21	carboxyl	carboxyl	NOUN
admet-189	147	22	-	-	PUNCT
admet-189	147	23	terminal	terminal	ADJ
admet-189	147	24	hydrolase	hydrolase	NOUN
admet-189	147	25	l1	l1	PROPN
admet-189	147	26	)	)	PUNCT
admet-189	147	27	act	act	VERB
admet-189	147	28	concomitant	concomitant	ADJ
admet-189	147	29	with	with	ADP
admet-189	147	30	an	an	DET
admet-189	147	31	increased	increase	VERB
admet-189	147	32	mitochondrial	mitochondrial	ADJ
admet-189	147	33	dysfunction	dysfunction	NOUN
admet-189	147	34	and	and	CCONJ
admet-189	147	35	oxidative	oxidative	ADJ
admet-189	147	36	damage	damage	NOUN
admet-189	147	37	in	in	ADP
admet-189	147	38	pd	pd	PROPN
admet-189	147	39	patients	patient	NOUN
admet-189	147	40	[	[	X
admet-189	147	41	20	20	NUM
admet-189	147	42	]	]	PUNCT
admet-189	147	43	.	.	PUNCT
admet-189	148	1	song	song	PROPN
admet-189	148	2	et	et	PROPN
admet-189	148	3	al	al	PROPN
admet-189	148	4	.	.	PROPN
admet-189	149	1	(	(	PUNCT
admet-189	149	2	2004	2004	NUM
admet-189	149	3	)	)	PUNCT
admet-189	149	4	reported	report	VERB
admet-189	149	5	a	a	DET
admet-189	149	6	co	co	NOUN
admet-189	149	7	-	-	NOUN
admet-189	149	8	relation	relation	NOUN
admet-189	149	9	between	between	ADP
admet-189	149	10	α	α	NOUN
admet-189	149	11	-	-	PUNCT
admet-189	149	12	synuclein	synuclein	NOUN
admet-189	149	13	and	and	CCONJ
admet-189	149	14	mitochondrial	mitochondrial	ADJ
admet-189	149	15	function	function	NOUN
admet-189	149	16	,	,	PUNCT
admet-189	149	17	since	since	SCONJ
admet-189	149	18	α	α	NOUN
admet-189	149	19	-	-	PUNCT
admet-189	149	20	synuclein	synuclein	NOUN
admet-189	149	21	transgenic	transgenic	NOUN
admet-189	149	22	mice	mouse	NOUN
admet-189	149	23	were	be	AUX
admet-189	149	24	susceptible	susceptible	ADJ
admet-189	149	25	to	to	ADP
admet-189	149	26	neurotoxic	neurotoxic	ADJ
admet-189	149	27	effects	effect	NOUN
admet-189	149	28	induced	induce	VERB
admet-189	149	29	by	by	ADP
admet-189	149	30	mptp	mptp	NOUN
admet-189	149	31	whereas	whereas	SCONJ
admet-189	149	32	,	,	PUNCT
admet-189	149	33	resistance	resistance	NOUN
admet-189	149	34	was	be	AUX
admet-189	149	35	observed	observe	VERB
admet-189	149	36	in	in	ADP
admet-189	149	37	α	α	NOUN
admet-189	149	38	-	-	PUNCT
admet-189	149	39	synuclein	synuclein	NOUN
admet-189	149	40	knockout	knockout	NOUN
admet-189	149	41	mice	mouse	NOUN
admet-189	150	1	[	[	X
admet-189	150	2	20	20	NUM
admet-189	150	3	]	]	PUNCT
admet-189	150	4	.	.	PUNCT
admet-189	151	1	sheng	sheng	PROPN
admet-189	151	2	et	et	PROPN
admet-189	151	3	al	al	PROPN
admet-189	151	4	.	.	PROPN
admet-189	151	5	reported	report	VERB
admet-189	151	6	the	the	DET
admet-189	151	7	up	up	ADJ
admet-189	151	8	-	-	PUNCT
admet-189	151	9	regulation	regulation	NOUN
admet-189	151	10	or	or	CCONJ
admet-189	151	11	mutation	mutation	NOUN
admet-189	151	12	in	in	ADP
admet-189	151	13	α	α	NOUN
admet-189	151	14	-	-	PUNCT
admet-189	151	15	synuclein	synuclein	NOUN
admet-189	151	16	leads	lead	VERB
admet-189	151	17	to	to	ADP
admet-189	151	18	formation	formation	NOUN
admet-189	151	19	of	of	ADP
admet-189	151	20	abnormal	abnormal	ADJ
admet-189	151	21	and	and	CCONJ
admet-189	151	22	misfolded	misfolde	VERB
admet-189	151	23	proteins	protein	NOUN
admet-189	151	24	through	through	ADP
admet-189	151	25	series	series	NOUN
admet-189	151	26	of	of	ADP
admet-189	151	27	events	event	NOUN
admet-189	151	28	like	like	ADP
admet-189	151	29	oligomerization	oligomerization	NOUN
admet-189	151	30	,	,	PUNCT
admet-189	151	31	fibrilization	fibrilization	NOUN
admet-189	151	32	and	and	CCONJ
admet-189	151	33	aggregation	aggregation	NOUN
admet-189	151	34	within	within	ADP
admet-189	151	35	the	the	DET
admet-189	151	36	nerve	nerve	NOUN
admet-189	151	37	cells	cell	NOUN
admet-189	151	38	(	(	PUNCT
admet-189	151	39	formation	formation	NOUN
admet-189	151	40	of	of	ADP
admet-189	151	41	lewy	lewy	ADJ
admet-189	151	42	bodies	body	NOUN
admet-189	151	43	)	)	PUNCT
admet-189	151	44	that	that	PRON
admet-189	151	45	responsible	responsible	ADJ
admet-189	151	46	for	for	ADP
admet-189	151	47	mitochondrial	mitochondrial	ADJ
admet-189	151	48	dysfunction	dysfunction	NOUN
admet-189	151	49	,	,	PUNCT
admet-189	151	50	impaired	impair	VERB
admet-189	151	51	neuronal	neuronal	ADJ
admet-189	151	52	homeostasis	homeostasis	NOUN
admet-189	151	53	and	and	CCONJ
admet-189	151	54	lead	lead	VERB
admet-189	151	55	to	to	ADP
admet-189	151	56	subsequent	subsequent	ADJ
admet-189	151	57	neurodegeneration	neurodegeneration	NOUN
admet-189	152	1	[	[	X
admet-189	152	2	21	21	NUM
admet-189	152	3	]	]	PUNCT
admet-189	152	4	.	.	PUNCT
admet-189	153	1	several	several	ADJ
admet-189	153	2	studies	study	NOUN
admet-189	153	3	reported	report	VERB
admet-189	153	4	the	the	DET
admet-189	153	5	role	role	NOUN
admet-189	153	6	of	of	ADP
admet-189	153	7	genetic	genetic	ADJ
admet-189	153	8	factors	factor	NOUN
admet-189	153	9	in	in	ADP
admet-189	153	10	pathogenesis	pathogenesis	NOUN
admet-189	153	11	of	of	ADP
admet-189	153	12	pd	pd	NOUN
admet-189	153	13	such	such	ADJ
admet-189	153	14	as	as	ADP
admet-189	153	15	extensive	extensive	ADJ
admet-189	153	16	generation	generation	NOUN
admet-189	153	17	of	of	ADP
admet-189	153	18	lewy	lewy	PROPN
admet-189	153	19	bodies	body	NOUN
admet-189	153	20	one	one	NUM
admet-189	153	21	of	of	ADP
admet-189	153	22	the	the	DET
admet-189	153	23	pathophysiological	pathophysiological	ADJ
admet-189	153	24	hallmarks	hallmark	NOUN
admet-189	153	25	associated	associate	VERB
admet-189	153	26	with	with	ADP
admet-189	153	27	mutated	mutate	VERB
admet-189	153	28	α	α	NOUN
admet-189	153	29	-	-	PUNCT
admet-189	153	30	synuclein	synuclein	NOUN
admet-189	153	31	causing	cause	VERB
admet-189	153	32	early	early	ADJ
admet-189	153	33	and	and	CCONJ
admet-189	153	34	late	late	ADJ
admet-189	153	35	onset	onset	NOUN
admet-189	153	36	of	of	ADP
admet-189	153	37	pd	pd	PROPN
admet-189	153	38	with	with	ADP
admet-189	153	39	rapid	rapid	ADJ
admet-189	153	40	disease	disease	NOUN
admet-189	153	41	progression	progression	NOUN
admet-189	153	42	whereas	whereas	SCONJ
admet-189	153	43	,	,	PUNCT
admet-189	153	44	mutated	mutate	VERB
admet-189	153	45	lrrk2	lrrk2	NOUN
admet-189	153	46	showed	show	VERB
admet-189	153	47	late	late	ADJ
admet-189	153	48	onset	onset	NOUN
admet-189	153	49	of	of	ADP
admet-189	153	50	pd	pd	PROPN
admet-189	153	51	(	(	PUNCT
admet-189	153	52	at	at	ADP
admet-189	153	53	80	80	NUM
admet-189	153	54	years	year	NOUN
admet-189	153	55	of	of	ADP
admet-189	153	56	age	age	NOUN
admet-189	153	57	)	)	PUNCT
admet-189	153	58	with	with	ADP
admet-189	153	59	lewy	lewy	PROPN
admet-189	153	60	bodies	body	NOUN
admet-189	153	61	formation	formation	NOUN
admet-189	153	62	,	,	PUNCT
admet-189	153	63	however	however	SCONJ
admet-189	153	64	dementia	dementia	NOUN
admet-189	153	65	was	be	AUX
admet-189	153	66	not	not	PART
admet-189	153	67	observed	observe	VERB
admet-189	153	68	and	and	CCONJ
admet-189	153	69	also	also	ADV
admet-189	153	70	mutated	mutate	VERB
admet-189	153	71	atp13a2	atp13a2	NOUN
admet-189	153	72	cause	cause	VERB
admet-189	153	73	an	an	DET
admet-189	153	74	atypical	atypical	ADJ
admet-189	153	75	pd	pd	NOUN
admet-189	153	76	with	with	ADP
admet-189	153	77	dementia	dementia	NOUN
admet-189	154	1	[	[	X
admet-189	154	2	22	22	NUM
admet-189	154	3	-	-	SYM
admet-189	154	4	24	24	NUM
admet-189	154	5	]	]	PUNCT
admet-189	154	6	.	.	PUNCT
admet-189	155	1	another	another	DET
admet-189	155	2	study	study	NOUN
admet-189	155	3	demonstrated	demonstrate	VERB
admet-189	155	4	that	that	SCONJ
admet-189	155	5	activated	activate	VERB
admet-189	155	6	macrophages	macrophage	NOUN
admet-189	155	7	and	and	CCONJ
admet-189	155	8	microglia	microglia	NOUN
admet-189	155	9	responsible	responsible	ADJ
admet-189	155	10	for	for	ADP
admet-189	155	11	secretion	secretion	NOUN
admet-189	155	12	of	of	ADP
admet-189	155	13	different	different	ADJ
admet-189	155	14	neurotrophic	neurotrophic	ADJ
admet-189	155	15	factors	factor	NOUN
admet-189	155	16	like	like	ADP
admet-189	155	17	brain	brain	NOUN
admet-189	155	18	derived	derive	VERB
admet-189	155	19	neurotrophic	neurotrophic	ADJ
admet-189	155	20	factor	factor	NOUN
admet-189	155	21	(	(	PUNCT
admet-189	155	22	bdnf	bdnf	PROPN
admet-189	155	23	)	)	PUNCT
admet-189	155	24	,	,	PUNCT
admet-189	155	25	and	and	CCONJ
admet-189	155	26	glial	glial	ADJ
admet-189	155	27	derived	derive	VERB
admet-189	155	28	neurotrophic	neurotrophic	ADJ
admet-189	155	29	factor	factor	NOUN
admet-189	155	30	(	(	PUNCT
admet-189	155	31	gdnf	gdnf	NOUN
admet-189	155	32	)	)	PUNCT
admet-189	155	33	cause	cause	VERB
admet-189	155	34	dopaminergic	dopaminergic	ADJ
admet-189	155	35	sprouting	sprouting	NOUN
admet-189	155	36	in	in	ADP
admet-189	155	37	nigrostriatal	nigrostriatal	ADJ
admet-189	155	38	injury	injury	NOUN
admet-189	155	39	in	in	ADP
admet-189	155	40	pd	pd	PROPN
admet-189	155	41	patients	patient	NOUN
admet-189	155	42	[	[	X
admet-189	155	43	25	25	NUM
admet-189	155	44	]	]	PUNCT
admet-189	155	45	.	.	PUNCT
admet-189	156	1	paul	paul	PROPN
admet-189	156	2	and	and	CCONJ
admet-189	156	3	colleagues	colleague	NOUN
admet-189	156	4	reported	report	VERB
admet-189	156	5	the	the	DET
admet-189	156	6	significant	significant	ADJ
admet-189	156	7	role	role	NOUN
admet-189	156	8	of	of	ADP
admet-189	156	9	ubiquitin	ubiquitin	ADJ
admet-189	156	10	–	–	PUNCT
admet-189	156	11	proteasome	proteasome	NOUN
admet-189	156	12	system	system	NOUN
admet-189	156	13	(	(	PUNCT
admet-189	156	14	ups	up	NOUN
admet-189	156	15	)	)	PUNCT
admet-189	156	16	and	and	CCONJ
admet-189	156	17	autophagy	autophagy	NOUN
admet-189	156	18	(	(	PUNCT
admet-189	156	19	macroautophagy	macroautophagy	ADJ
admet-189	156	20	)	)	PUNCT
admet-189	156	21	pathways	pathway	NOUN
admet-189	156	22	in	in	ADP
admet-189	156	23	lysosomal	lysosomal	ADJ
admet-189	156	24	and	and	CCONJ
admet-189	156	25	proteasomal	proteasomal	ADJ
admet-189	156	26	dysfunction	dysfunction	NOUN
admet-189	156	27	,	,	PUNCT
admet-189	156	28	another	another	DET
admet-189	156	29	pathophysiological	pathophysiological	ADJ
admet-189	156	30	hallmark	hallmark	NOUN
admet-189	156	31	of	of	ADP
admet-189	156	32	pd	pd	PROPN
admet-189	156	33	[	[	X
admet-189	156	34	26	26	NUM
admet-189	156	35	]	]	PUNCT
admet-189	156	36	.	.	PUNCT
admet-189	157	1	further	further	PROPN
admet-189	157	2	studies	study	NOUN
admet-189	157	3	reported	report	VERB
admet-189	157	4	the	the	DET
admet-189	157	5	damage	damage	NOUN
admet-189	157	6	to	to	ADP
admet-189	157	7	ups	up	NOUN
admet-189	157	8	and	and	CCONJ
admet-189	157	9	lysosomal	lysosomal	ADJ
admet-189	157	10	pathways	pathway	NOUN
admet-189	157	11	(	(	PUNCT
admet-189	157	12	increased	increase	VERB
admet-189	157	13	protein	protein	NOUN
admet-189	157	14	accumulation	accumulation	NOUN
admet-189	157	15	due	due	ADP
admet-189	157	16	to	to	ADP
admet-189	157	17	impaired	impaired	ADJ
admet-189	157	18	unwanted	unwanted	ADJ
admet-189	157	19	protein	protein	NOUN
admet-189	157	20	clearance	clearance	NOUN
admet-189	157	21	mechanism	mechanism	NOUN
admet-189	157	22	)	)	PUNCT
admet-189	157	23	through	through	ADP
admet-189	157	24	mutated	mutate	VERB
admet-189	157	25	genes	gene	NOUN
admet-189	157	26	like	like	ADP
admet-189	157	27	parkin	parkin	NOUN
admet-189	157	28	,	,	PUNCT
admet-189	157	29	lrrk2	lrrk2	NOUN
admet-189	157	30	causing	cause	VERB
admet-189	157	31	neuronal	neuronal	ADJ
admet-189	157	32	toxic	toxic	ADJ
admet-189	157	33	insult	insult	NOUN
admet-189	157	34	in	in	ADP
admet-189	157	35	pd	pd	PROPN
admet-189	157	36	[	[	X
admet-189	157	37	27	27	NUM
admet-189	157	38	]	]	PUNCT
admet-189	157	39	.	.	PUNCT
admet-189	158	1	r.	r.	PROPN
admet-189	158	2	banerjee	banerjee	PROPN
admet-189	158	3	et	et	PROPN
admet-189	158	4	al	al	PROPN
admet-189	158	5	.	.	PROPN
admet-189	158	6	admet	admet	PROPN
admet-189	158	7	&	&	CCONJ
admet-189	158	8	dmpk	dmpk	PROPN
admet-189	158	9	3(3	3(3	NUM
admet-189	158	10	)	)	PUNCT
admet-189	158	11	(	(	PUNCT
admet-189	158	12	2015	2015	NUM
admet-189	158	13	)	)	PUNCT
admet-189	158	14	155	155	NUM
admet-189	158	15	-	-	SYM
admet-189	158	16	181	181	NUM
admet-189	158	17	158	158	NUM
admet-189	158	18	impaired	impaired	ADJ
admet-189	158	19	iron	iron	NOUN
admet-189	158	20	metabolism	metabolism	NOUN
admet-189	158	21	concomitant	concomitant	NOUN
admet-189	158	22	with	with	ADP
admet-189	158	23	different	different	ADJ
admet-189	158	24	genetic	genetic	ADJ
admet-189	158	25	(	(	PUNCT
admet-189	158	26	α	α	NOUN
admet-189	158	27	-	-	PUNCT
admet-189	158	28	synuclein	synuclein	NOUN
admet-189	158	29	aggregation	aggregation	NOUN
admet-189	158	30	)	)	PUNCT
admet-189	158	31	and	and	CCONJ
admet-189	158	32	environmental	environmental	ADJ
admet-189	158	33	(	(	PUNCT
admet-189	158	34	tobacco	tobacco	NOUN
admet-189	158	35	,	,	PUNCT
admet-189	158	36	cigarette	cigarette	NOUN
admet-189	158	37	smoking	smoking	NOUN
admet-189	158	38	)	)	PUNCT
admet-189	158	39	factors	factor	NOUN
admet-189	158	40	was	be	AUX
admet-189	158	41	observed	observe	VERB
admet-189	158	42	in	in	ADP
admet-189	158	43	pathogenesis	pathogenesis	NOUN
admet-189	158	44	of	of	ADP
admet-189	158	45	sporadic	sporadic	ADJ
admet-189	158	46	or	or	CCONJ
admet-189	158	47	familial	familial	ADJ
admet-189	158	48	pd	pd	NOUN
admet-189	158	49	[	[	X
admet-189	158	50	28	28	NUM
admet-189	158	51	]	]	PUNCT
admet-189	158	52	.	.	PUNCT
admet-189	159	1	mitochondrial	mitochondrial	ADJ
admet-189	159	2	byproducts	byproduct	NOUN
admet-189	159	3	(	(	PUNCT
admet-189	159	4	peroxide	peroxide	NOUN
admet-189	159	5	and	and	CCONJ
admet-189	159	6	superoxide	superoxide	NOUN
admet-189	159	7	)	)	PUNCT
admet-189	159	8	can	can	AUX
admet-189	159	9	reactive	reactive	VERB
admet-189	159	10	with	with	ADP
admet-189	159	11	iron	iron	NOUN
admet-189	159	12	by	by	ADP
admet-189	159	13	generating	generate	VERB
admet-189	159	14	most	most	ADV
admet-189	159	15	damaging	damaging	ADJ
admet-189	159	16	hydroxyl	hydroxyl	NOUN
admet-189	159	17	radicals	radical	NOUN
admet-189	159	18	causing	cause	VERB
admet-189	159	19	dopaminergic	dopaminergic	ADJ
admet-189	159	20	cell	cell	NOUN
admet-189	159	21	death	death	NOUN
admet-189	159	22	in	in	ADP
admet-189	159	23	substantia	substantia	NOUN
admet-189	159	24	nigra	nigra	PROPN
admet-189	159	25	.	.	PUNCT
admet-189	160	1	these	these	DET
admet-189	160	2	findings	finding	NOUN
admet-189	160	3	further	far	ADV
admet-189	160	4	supported	support	VERB
admet-189	160	5	by	by	ADP
admet-189	160	6	chronic	chronic	ADJ
admet-189	160	7	mptp	mptp	NOUN
admet-189	160	8	treated	treat	VERB
admet-189	160	9	mouse	mouse	NOUN
admet-189	160	10	studies	study	NOUN
admet-189	160	11	correlating	correlate	VERB
admet-189	160	12	iron	iron	NOUN
admet-189	160	13	levels	level	NOUN
admet-189	160	14	with	with	ADP
admet-189	160	15	selective	selective	ADJ
admet-189	160	16	dopamine	dopamine	NOUN
admet-189	160	17	degeneration	degeneration	NOUN
admet-189	160	18	through	through	ADP
admet-189	160	19	lipofuscin	lipofuscin	NOUN
admet-189	160	20	aggregation	aggregation	NOUN
admet-189	160	21	and	and	CCONJ
admet-189	160	22	up	up	ADV
admet-189	160	23	-	-	PUNCT
admet-189	160	24	regulated	regulate	VERB
admet-189	160	25	α	α	NOUN
admet-189	160	26	-	-	PUNCT
admet-189	160	27	synuclein	synuclein	NOUN
admet-189	160	28	[	[	X
admet-189	160	29	29	29	NUM
admet-189	160	30	]	]	PUNCT
admet-189	160	31	.	.	PUNCT
admet-189	161	1	pla2g6	pla2g6	NOUN
admet-189	161	2	and	and	CCONJ
admet-189	161	3	atp13a2	atp13a2	NOUN
admet-189	161	4	are	be	AUX
admet-189	161	5	two	two	NUM
admet-189	161	6	important	important	ADJ
admet-189	161	7	genetic	genetic	ADJ
admet-189	161	8	factors	factor	NOUN
admet-189	161	9	associated	associate	VERB
admet-189	161	10	with	with	ADP
admet-189	161	11	increased	increase	VERB
admet-189	161	12	neurodegeneration	neurodegeneration	NOUN
admet-189	161	13	in	in	ADP
admet-189	161	14	brain	brain	NOUN
admet-189	161	15	.	.	PUNCT
admet-189	162	1	iron	iron	NOUN
admet-189	162	2	accumulating	accumulate	VERB
admet-189	162	3	in	in	ADP
admet-189	162	4	substantia	substantia	NOUN
admet-189	162	5	nigra	nigra	PROPN
admet-189	162	6	of	of	ADP
admet-189	162	7	pd	pd	PROPN
admet-189	162	8	patients	patient	NOUN
admet-189	162	9	have	have	AUX
admet-189	162	10	been	be	AUX
admet-189	162	11	reported	report	VERB
admet-189	162	12	by	by	ADP
admet-189	162	13	several	several	ADJ
admet-189	162	14	studies	study	NOUN
admet-189	162	15	however	however	ADV
admet-189	162	16	their	their	PRON
admet-189	162	17	precise	precise	ADJ
admet-189	162	18	mechanism	mechanism	NOUN
admet-189	162	19	of	of	ADP
admet-189	162	20	action	action	NOUN
admet-189	162	21	is	be	AUX
admet-189	162	22	not	not	PART
admet-189	162	23	yet	yet	ADV
admet-189	162	24	clear	clear	ADJ
admet-189	163	1	[	[	X
admet-189	163	2	30,31	30,31	NUM
admet-189	163	3	]	]	PUNCT
admet-189	163	4	.	.	PUNCT
admet-189	164	1	despite	despite	SCONJ
admet-189	164	2	the	the	DET
admet-189	164	3	significant	significant	ADJ
admet-189	164	4	progress	progress	NOUN
admet-189	164	5	in	in	ADP
admet-189	164	6	molecular	molecular	ADJ
admet-189	164	7	and	and	CCONJ
admet-189	164	8	cellular	cellular	ADJ
admet-189	164	9	studies	study	NOUN
admet-189	164	10	,	,	PUNCT
admet-189	164	11	the	the	DET
admet-189	164	12	detailed	detailed	ADJ
admet-189	164	13	pathophysiology	pathophysiology	NOUN
admet-189	164	14	of	of	ADP
admet-189	164	15	pd	pd	PROPN
admet-189	164	16	is	be	AUX
admet-189	164	17	not	not	PART
admet-189	164	18	yet	yet	ADV
admet-189	164	19	clear	clear	ADJ
admet-189	164	20	.	.	PUNCT
admet-189	165	1	present	present	ADJ
admet-189	165	2	modalities	modality	NOUN
admet-189	165	3	of	of	ADP
admet-189	165	4	management	management	NOUN
admet-189	165	5	and	and	CCONJ
admet-189	165	6	their	their	PRON
admet-189	165	7	limitations	limitation	NOUN
admet-189	165	8	current	current	ADJ
admet-189	165	9	techniques	technique	NOUN
admet-189	165	10	for	for	ADP
admet-189	165	11	diagnosis	diagnosis	NOUN
admet-189	165	12	of	of	ADP
admet-189	165	13	pdclinical	pdclinical	ADJ
admet-189	165	14	diagnosis	diagnosis	NOUN
admet-189	165	15	and	and	CCONJ
admet-189	165	16	imaging	imaging	NOUN
admet-189	165	17	accurate	accurate	ADJ
admet-189	165	18	diagnosis	diagnosis	NOUN
admet-189	165	19	plays	play	VERB
admet-189	165	20	an	an	DET
admet-189	165	21	important	important	ADJ
admet-189	165	22	role	role	NOUN
admet-189	165	23	in	in	ADP
admet-189	165	24	the	the	DET
admet-189	165	25	precise	precise	ADJ
admet-189	165	26	management	management	NOUN
admet-189	165	27	of	of	ADP
admet-189	165	28	pd	pd	PROPN
admet-189	165	29	.	.	PROPN
admet-189	165	30	currently	currently	ADV
admet-189	165	31	,	,	PUNCT
admet-189	165	32	diagnosis	diagnosis	NOUN
admet-189	165	33	of	of	ADP
admet-189	165	34	pd	pd	PROPN
admet-189	165	35	is	be	AUX
admet-189	165	36	done	do	VERB
admet-189	165	37	on	on	ADP
admet-189	165	38	the	the	DET
admet-189	165	39	basis	basis	NOUN
admet-189	165	40	of	of	ADP
admet-189	165	41	different	different	ADJ
admet-189	165	42	clinical	clinical	ADJ
admet-189	165	43	symptoms	symptom	NOUN
admet-189	165	44	of	of	ADP
admet-189	165	45	parkinsonism	parkinsonism	NOUN
admet-189	165	46	like	like	ADP
admet-189	165	47	bradykinesia	bradykinesia	PROPN
admet-189	165	48	,	,	PUNCT
admet-189	165	49	tremor	tremor	NOUN
admet-189	165	50	,	,	PUNCT
admet-189	165	51	postural	postural	ADJ
admet-189	165	52	imbalance	imbalance	NOUN
admet-189	165	53	,	,	PUNCT
admet-189	165	54	dementia	dementia	NOUN
admet-189	165	55	,	,	PUNCT
admet-189	165	56	sleep	sleep	NOUN
admet-189	165	57	disorders	disorder	NOUN
admet-189	165	58	,	,	PUNCT
admet-189	165	59	sialorrhea	sialorrhea	ADJ
admet-189	165	60	,	,	PUNCT
admet-189	165	61	dry	dry	ADJ
admet-189	165	62	eyes	eye	NOUN
admet-189	165	63	syndromes	syndrome	NOUN
admet-189	165	64	and	and	CCONJ
admet-189	165	65	olfactory	olfactory	ADJ
admet-189	165	66	disturbances	disturbance	NOUN
admet-189	165	67	,	,	PUNCT
admet-189	165	68	fatigue	fatigue	NOUN
admet-189	165	69	,	,	PUNCT
admet-189	165	70	weight	weight	NOUN
admet-189	165	71	changes	change	NOUN
admet-189	165	72	[	[	X
admet-189	165	73	32	32	NUM
admet-189	165	74	]	]	PUNCT
admet-189	165	75	.	.	PUNCT
admet-189	166	1	presence	presence	NOUN
admet-189	166	2	of	of	ADP
admet-189	166	3	lewy	lewy	PROPN
admet-189	166	4	bodies	body	NOUN
admet-189	166	5	in	in	ADP
admet-189	166	6	substantia	substantia	NOUN
admet-189	166	7	nigra	nigra	NOUN
admet-189	166	8	,	,	PUNCT
admet-189	166	9	hypothalamus	hypothalamus	PROPN
admet-189	166	10	,	,	PUNCT
admet-189	166	11	basal	basal	ADJ
admet-189	166	12	nuclei	nucleus	NOUN
admet-189	166	13	,	,	PUNCT
admet-189	166	14	and	and	CCONJ
admet-189	166	15	cranial	cranial	ADJ
admet-189	166	16	motor	motor	NOUN
admet-189	166	17	nerve	nerve	NOUN
admet-189	166	18	and	and	CCONJ
admet-189	166	19	its	its	PRON
admet-189	166	20	nuclei	nucleus	NOUN
admet-189	166	21	etc	etc	X
admet-189	166	22	.	.	X
admet-189	166	23	is	be	AUX
admet-189	166	24	an	an	DET
admet-189	166	25	important	important	ADJ
admet-189	166	26	biomarker	biomarker	NOUN
admet-189	166	27	for	for	ADP
admet-189	166	28	pd	pd	NOUN
admet-189	166	29	diagnosis	diagnosis	NOUN
admet-189	166	30	.	.	PUNCT
admet-189	167	1	different	different	ADJ
admet-189	167	2	genetic	genetic	ADJ
admet-189	167	3	and	and	CCONJ
admet-189	167	4	imaging	imaging	NOUN
admet-189	167	5	testing	testing	NOUN
admet-189	167	6	were	be	AUX
admet-189	167	7	carried	carry	VERB
admet-189	167	8	out	out	ADP
admet-189	167	9	for	for	ADP
admet-189	167	10	diagnosis	diagnosis	NOUN
admet-189	167	11	of	of	ADP
admet-189	167	12	pd	pd	PROPN
admet-189	167	13	.	.	PROPN
admet-189	167	14	identification	identification	NOUN
admet-189	167	15	of	of	ADP
admet-189	167	16	genetic	genetic	ADJ
admet-189	167	17	mutations	mutation	NOUN
admet-189	167	18	revealed	reveal	VERB
admet-189	167	19	that	that	SCONJ
admet-189	167	20	α	α	NOUN
admet-189	167	21	-	-	PUNCT
admet-189	167	22	synuclein	synuclein	NOUN
admet-189	167	23	,	,	PUNCT
admet-189	167	24	nurr1	nurr1	NOUN
admet-189	167	25	,	,	PUNCT
admet-189	167	26	lrrk2	lrrk2	NOUN
admet-189	167	27	and	and	CCONJ
admet-189	167	28	uch	uch	ADJ
admet-189	167	29	-	-	PUNCT
admet-189	167	30	l1	l1	PROPN
admet-189	167	31	are	be	AUX
admet-189	167	32	responsible	responsible	ADJ
admet-189	167	33	for	for	ADP
admet-189	167	34	autosomal	autosomal	ADJ
admet-189	167	35	-	-	PUNCT
admet-189	167	36	dominant	dominant	NOUN
admet-189	167	37	inheritance	inheritance	NOUN
admet-189	167	38	whereas	whereas	SCONJ
admet-189	167	39	,	,	PUNCT
admet-189	167	40	dj1	dj1	PROPN
admet-189	167	41	,	,	PUNCT
admet-189	167	42	parkin	parkin	NOUN
admet-189	167	43	and	and	CCONJ
admet-189	167	44	pink1	pink1	NOUN
admet-189	167	45	are	be	AUX
admet-189	167	46	responsible	responsible	ADJ
admet-189	167	47	for	for	ADP
admet-189	167	48	autosomal	autosomal	ADJ
admet-189	167	49	-	-	PUNCT
admet-189	167	50	recessive	recessive	ADJ
admet-189	167	51	inheritance	inheritance	NOUN
admet-189	168	1	[	[	X
admet-189	168	2	32	32	NUM
admet-189	168	3	]	]	PUNCT
admet-189	168	4	.	.	PUNCT
admet-189	169	1	the	the	DET
admet-189	169	2	cranial	cranial	ADJ
admet-189	169	3	ct	ct	PROPN
admet-189	169	4	scan	scan	NOUN
admet-189	169	5	,	,	PUNCT
admet-189	169	6	mri	mri	NOUN
admet-189	169	7	and	and	CCONJ
admet-189	169	8	pet	pet	NOUN
admet-189	169	9	(	(	PUNCT
admet-189	169	10	fluorine18	fluorine18	NOUN
admet-189	169	11	labeled	label	VERB
admet-189	169	12	dopa	dopa	NOUN
admet-189	169	13	)	)	PUNCT
admet-189	169	14	imaging	imaging	NOUN
admet-189	169	15	,	,	PUNCT
admet-189	169	16	spect	spect	NOUN
admet-189	169	17	(	(	PUNCT
admet-189	169	18	single	single	ADJ
admet-189	169	19	photon	photon	NOUN
admet-189	169	20	-	-	PUNCT
admet-189	169	21	emission	emission	NOUN
admet-189	169	22	computed	compute	VERB
admet-189	169	23	tomography	tomography	NOUN
admet-189	169	24	)	)	PUNCT
admet-189	169	25	and	and	CCONJ
admet-189	169	26	transcranial	transcranial	ADJ
admet-189	169	27	ultrasound	ultrasound	NOUN
admet-189	169	28	imaging	imaging	NOUN
admet-189	169	29	etc	etc	X
admet-189	169	30	.	.	X
admet-189	169	31	are	be	AUX
admet-189	169	32	valuable	valuable	ADJ
admet-189	169	33	techniques	technique	NOUN
admet-189	169	34	for	for	ADP
admet-189	169	35	differentiation	differentiation	NOUN
admet-189	169	36	and	and	CCONJ
admet-189	169	37	diagnosis	diagnosis	NOUN
admet-189	169	38	of	of	ADP
admet-189	169	39	pd	pd	PROPN
admet-189	169	40	from	from	ADP
admet-189	169	41	other	other	ADJ
admet-189	169	42	neurodegenerative	neurodegenerative	ADJ
admet-189	169	43	disorders	disorder	NOUN
admet-189	169	44	.	.	PUNCT
admet-189	170	1	for	for	ADP
admet-189	170	2	instance	instance	NOUN
admet-189	170	3	,	,	PUNCT
admet-189	170	4	spect	spect	ADJ
admet-189	170	5	tracer	tracer	NOUN
admet-189	170	6	used	use	VERB
admet-189	170	7	for	for	ADP
admet-189	170	8	presynaptic	presynaptic	ADJ
admet-189	170	9	dopamine	dopamine	NOUN
admet-189	170	10	transporter	transporter	NOUN
admet-189	170	11	imaging	imaging	NOUN
admet-189	170	12	like	like	ADP
admet-189	170	13	fp	fp	X
admet-189	170	14	-	-	PUNCT
admet-189	170	15	cit	cit	ADJ
admet-189	170	16	(	(	PUNCT
admet-189	170	17	n	n	CCONJ
admet-189	170	18	-	-	PUNCT
admet-189	170	19	ω	ω	NOUN
admet-189	170	20	-	-	PUNCT
admet-189	170	21	fluoropropyl-2β	fluoropropyl-2β	NOUN
admet-189	170	22	-	-	PUNCT
admet-189	170	23	carbomethoxy-3β-(4	carbomethoxy-3β-(4	NUM
admet-189	170	24	-	-	PUNCT
admet-189	170	25	iodophenyl	iodophenyl	NOUN
admet-189	170	26	)	)	PUNCT
admet-189	170	27	nortropane	nortropane	NOUN
admet-189	170	28	binds	bind	VERB
admet-189	170	29	to	to	ADP
admet-189	170	30	the	the	DET
admet-189	170	31	dopamine	dopamine	NOUN
admet-189	170	32	transporters	transporter	NOUN
admet-189	170	33	(	(	PUNCT
admet-189	170	34	dat	dat	ADJ
admet-189	170	35	)	)	PUNCT
admet-189	170	36	protein	protein	NOUN
admet-189	170	37	.	.	PUNCT
admet-189	171	1	thus	thus	ADV
admet-189	171	2	,	,	PUNCT
admet-189	171	3	integrity	integrity	NOUN
admet-189	171	4	of	of	ADP
admet-189	171	5	nigrostriatal	nigrostriatal	ADJ
admet-189	171	6	dopaminergic	dopaminergic	ADJ
admet-189	171	7	transporter	transporter	NOUN
admet-189	171	8	can	can	AUX
admet-189	171	9	be	be	AUX
admet-189	171	10	used	use	VERB
admet-189	171	11	as	as	ADP
admet-189	171	12	a	a	DET
admet-189	171	13	diagnostic	diagnostic	ADJ
admet-189	171	14	marker	marker	NOUN
admet-189	171	15	for	for	ADP
admet-189	171	16	detection	detection	NOUN
admet-189	171	17	of	of	ADP
admet-189	171	18	early	early	ADJ
admet-189	171	19	pd	pd	PROPN
admet-189	171	20	progression	progression	NOUN
admet-189	171	21	[	[	X
admet-189	171	22	33	33	NUM
admet-189	171	23	]	]	PUNCT
admet-189	171	24	.	.	PUNCT
admet-189	172	1	however	however	ADV
admet-189	172	2	,	,	PUNCT
admet-189	172	3	accessibility	accessibility	NOUN
admet-189	172	4	and	and	CCONJ
admet-189	172	5	cost	cost	NOUN
admet-189	172	6	of	of	ADP
admet-189	172	7	these	these	DET
admet-189	172	8	techniques	technique	NOUN
admet-189	172	9	restrict	restrict	VERB
admet-189	172	10	their	their	PRON
admet-189	172	11	usefulness	usefulness	NOUN
admet-189	172	12	and	and	CCONJ
admet-189	172	13	application	application	NOUN
admet-189	172	14	in	in	ADP
admet-189	172	15	diagnosis	diagnosis	NOUN
admet-189	172	16	of	of	ADP
admet-189	172	17	pd	pd	PROPN
admet-189	172	18	.	.	PROPN
admet-189	172	19	pharmacotherapy	pharmacotherapy	NOUN
admet-189	172	20	and	and	CCONJ
admet-189	172	21	management	management	NOUN
admet-189	172	22	of	of	ADP
admet-189	172	23	parkinson	parkinson	NOUN
admet-189	172	24	’s	’s	PART
admet-189	172	25	disease	disease	NOUN
admet-189	172	26	currently	currently	ADV
admet-189	172	27	different	different	ADJ
admet-189	172	28	therapies	therapy	NOUN
admet-189	172	29	are	be	AUX
admet-189	172	30	available	available	ADJ
admet-189	172	31	for	for	ADP
admet-189	172	32	treatment	treatment	NOUN
admet-189	172	33	of	of	ADP
admet-189	172	34	motor	motor	NOUN
admet-189	172	35	and	and	CCONJ
admet-189	172	36	non	non	ADJ
admet-189	172	37	-	-	ADJ
admet-189	172	38	motor	motor	ADJ
admet-189	172	39	complications	complication	NOUN
admet-189	172	40	associated	associate	VERB
admet-189	172	41	with	with	ADP
admet-189	172	42	pd	pd	PROPN
admet-189	172	43	.	.	PROPN
admet-189	172	44	pharmacotherapy	pharmacotherapy	NOUN
admet-189	172	45	of	of	ADP
admet-189	172	46	pd	pd	PROPN
admet-189	172	47	includes	include	VERB
admet-189	172	48	treatment	treatment	NOUN
admet-189	172	49	with	with	ADP
admet-189	172	50	drugs	drug	NOUN
admet-189	172	51	like	like	ADP
admet-189	172	52	l	l	NOUN
admet-189	172	53	-	-	NOUN
admet-189	172	54	dopa	dopa	NOUN
admet-189	172	55	,	,	PUNCT
admet-189	172	56	dopamine	dopamine	NOUN
admet-189	172	57	receptor	receptor	NOUN
admet-189	172	58	agonist	agonist	NOUN
admet-189	172	59	,	,	PUNCT
admet-189	172	60	catechol	catechol	NOUN
admet-189	172	61	-	-	PUNCT
admet-189	172	62	o	o	NOUN
admet-189	172	63	-	-	NOUN
admet-189	172	64	methyltransferase	methyltransferase	ADJ
admet-189	172	65	(	(	PUNCT
admet-189	172	66	comt	comt	NOUN
admet-189	172	67	)	)	PUNCT
admet-189	172	68	inhibitors	inhibitor	NOUN
admet-189	172	69	,	,	PUNCT
admet-189	172	70	antagonists	antagonist	NOUN
admet-189	172	71	of	of	ADP
admet-189	172	72	mao	mao	PROPN
admet-189	172	73	-	-	PUNCT
admet-189	172	74	b	b	PROPN
admet-189	172	75	and	and	CCONJ
admet-189	172	76	glutamate	glutamate	NOUN
admet-189	172	77	and	and	CCONJ
admet-189	172	78	amantadine	amantadine	NOUN
admet-189	172	79	etc	etc	X
admet-189	172	80	.	.	PUNCT
admet-189	173	1	l	l	NOUN
admet-189	173	2	-	-	NOUN
admet-189	173	3	dopa	dopa	NOUN
admet-189	173	4	is	be	AUX
admet-189	173	5	most	most	ADV
admet-189	173	6	widely	widely	ADV
admet-189	173	7	used	use	VERB
admet-189	173	8	therapy	therapy	NOUN
admet-189	173	9	for	for	ADP
admet-189	173	10	treatment	treatment	NOUN
admet-189	173	11	of	of	ADP
admet-189	173	12	pd	pd	NOUN
admet-189	173	13	because	because	SCONJ
admet-189	173	14	it	it	PRON
admet-189	173	15	easily	easily	ADV
admet-189	173	16	crosses	cross	VERB
admet-189	173	17	bbb	bbb	PROPN
admet-189	173	18	and	and	CCONJ
admet-189	173	19	is	be	AUX
admet-189	173	20	converted	convert	VERB
admet-189	173	21	into	into	ADP
admet-189	173	22	dopamine	dopamine	NOUN
admet-189	173	23	in	in	ADP
admet-189	173	24	presence	presence	NOUN
admet-189	173	25	of	of	ADP
admet-189	173	26	an	an	DET
admet-189	173	27	enzyme	enzyme	NOUN
admet-189	173	28	dopa	dopa	NOUN
admet-189	173	29	-	-	PUNCT
admet-189	173	30	decarboxylase	decarboxylase	NOUN
admet-189	173	31	.	.	PUNCT
admet-189	174	1	however	however	ADV
admet-189	174	2	,	,	PUNCT
admet-189	174	3	long	long	ADJ
admet-189	174	4	term	term	NOUN
admet-189	174	5	treatment	treatment	NOUN
admet-189	174	6	with	with	ADP
admet-189	174	7	l	l	NOUN
admet-189	174	8	-	-	PUNCT
admet-189	174	9	dopa	dopa	NOUN
admet-189	174	10	results	result	NOUN
admet-189	174	11	in	in	ADP
admet-189	174	12	various	various	ADJ
admet-189	174	13	side	side	NOUN
admet-189	174	14	effects	effect	NOUN
admet-189	174	15	like	like	ADP
admet-189	174	16	dyskinesia	dyskinesia	NOUN
admet-189	174	17	(	(	PUNCT
admet-189	174	18	involuntary	involuntary	ADJ
admet-189	174	19	and	and	CCONJ
admet-189	174	20	non	non	ADJ
admet-189	174	21	-	-	ADJ
admet-189	174	22	rhythmic	rhythmic	ADJ
admet-189	174	23	choreic	choreic	ADJ
admet-189	174	24	or	or	CCONJ
admet-189	174	25	choreodystonic	choreodystonic	ADJ
admet-189	174	26	movements	movement	NOUN
admet-189	174	27	)	)	PUNCT
admet-189	174	28	,	,	PUNCT
admet-189	174	29	alterations	alteration	NOUN
admet-189	174	30	in	in	ADP
admet-189	174	31	on	on	ADP
admet-189	174	32	-	-	PUNCT
admet-189	174	33	off	off	ADP
admet-189	174	34	periods	period	NOUN
admet-189	174	35	giving	give	VERB
admet-189	174	36	rise	rise	NOUN
admet-189	174	37	to	to	ADP
admet-189	174	38	motor	motor	NOUN
admet-189	174	39	fluctuations	fluctuation	NOUN
admet-189	174	40	,	,	PUNCT
admet-189	174	41	nausea	nausea	NOUN
admet-189	174	42	and	and	CCONJ
admet-189	174	43	vomiting	vomit	VERB
admet-189	175	1	[	[	X
admet-189	175	2	34	34	NUM
admet-189	175	3	]	]	PUNCT
admet-189	175	4	.	.	PUNCT
admet-189	176	1	therefore	therefore	ADV
admet-189	176	2	,	,	PUNCT
admet-189	176	3	in	in	ADP
admet-189	176	4	clinical	clinical	ADJ
admet-189	176	5	practice	practice	NOUN
admet-189	176	6	l	l	NOUN
admet-189	176	7	-	-	NOUN
admet-189	176	8	dopa	dopa	NOUN
admet-189	176	9	is	be	AUX
admet-189	176	10	co	co	VERB
admet-189	176	11	-	-	VERB
admet-189	176	12	administered	administer	VERB
admet-189	176	13	with	with	ADP
admet-189	176	14	carbidopa	carbidopa	NOUN
admet-189	176	15	(	(	PUNCT
admet-189	176	16	dopa	dopa	NOUN
admet-189	176	17	-	-	PUNCT
admet-189	176	18	decarboxylase	decarboxylase	NOUN
admet-189	176	19	inhibitor	inhibitor	NOUN
admet-189	176	20	)	)	PUNCT
admet-189	176	21	in	in	ADP
admet-189	176	22	which	which	PRON
admet-189	176	23	carbidopa	carbidopa	NOUN
admet-189	176	24	itself	itself	PRON
admet-189	176	25	does	do	AUX
admet-189	176	26	not	not	PART
admet-189	176	27	cross	cross	VERB
admet-189	176	28	bbb	bbb	NOUN
admet-189	176	29	but	but	CCONJ
admet-189	176	30	reduces	reduce	VERB
admet-189	176	31	conversion	conversion	NOUN
admet-189	176	32	of	of	ADP
admet-189	176	33	l	l	NOUN
admet-189	176	34	-	-	NOUN
admet-189	176	35	dopa	dopa	NOUN
admet-189	176	36	to	to	PART
admet-189	176	37	dopamine	dopamine	VERB
admet-189	176	38	in	in	ADP
admet-189	176	39	peripheral	peripheral	ADJ
admet-189	176	40	nervous	nervous	ADJ
admet-189	176	41	system	system	NOUN
admet-189	176	42	and	and	CCONJ
admet-189	176	43	thereby	thereby	ADV
admet-189	176	44	increase	increase	VERB
admet-189	176	45	its	its	PRON
admet-189	176	46	delivery	delivery	NOUN
admet-189	176	47	to	to	ADP
admet-189	176	48	the	the	DET
admet-189	176	49	brain	brain	NOUN
admet-189	176	50	[	[	X
admet-189	176	51	35	35	NUM
admet-189	176	52	]	]	PUNCT
admet-189	176	53	.	.	PUNCT
admet-189	177	1	comt	comt	PROPN
admet-189	177	2	inhibitors	inhibitor	NOUN
admet-189	177	3	(	(	PUNCT
admet-189	177	4	entacapone	entacapone	ADJ
admet-189	177	5	)	)	PUNCT
admet-189	177	6	are	be	AUX
admet-189	177	7	ineffective	ineffective	ADJ
admet-189	177	8	when	when	SCONJ
admet-189	177	9	administered	administer	VERB
admet-189	177	10	alone	alone	ADV
admet-189	177	11	,	,	PUNCT
admet-189	177	12	therefore	therefore	ADV
admet-189	177	13	they	they	PRON
admet-189	177	14	are	be	AUX
admet-189	177	15	administered	administer	VERB
admet-189	177	16	as	as	ADP
admet-189	177	17	adjuvants	adjuvant	NOUN
admet-189	177	18	with	with	ADP
admet-189	177	19	levodopa	levodopa	NOUN
admet-189	177	20	and	and	CCONJ
admet-189	177	21	carbidopa	carbidopa	NOUN
admet-189	177	22	in	in	ADP
admet-189	177	23	pd	pd	PROPN
admet-189	177	24	patients	patient	NOUN
admet-189	177	25	to	to	PART
admet-189	177	26	avoid	avoid	VERB
admet-189	177	27	end	end	NOUN
admet-189	177	28	-	-	PUNCT
admet-189	177	29	off	off	ADP
admet-189	177	30	-	-	PUNCT
admet-189	177	31	dose	dose	NOUN
admet-189	177	32	alterations	alteration	NOUN
admet-189	177	33	[	[	X
admet-189	177	34	36	36	NUM
admet-189	177	35	]	]	PUNCT
admet-189	177	36	.	.	PUNCT
admet-189	178	1	early	early	PROPN
admet-189	178	2	pd	pd	PROPN
admet-189	178	3	symptoms	symptom	NOUN
admet-189	178	4	are	be	AUX
admet-189	178	5	treated	treat	VERB
admet-189	178	6	with	with	ADP
admet-189	178	7	mao	mao	PROPN
admet-189	178	8	-	-	PUNCT
admet-189	178	9	b	b	NOUN
admet-189	178	10	inhibitors	inhibitor	NOUN
admet-189	178	11	like	like	ADP
admet-189	178	12	selegiline	selegiline	NOUN
admet-189	178	13	or	or	CCONJ
admet-189	178	14	rasagiline	rasagiline	NOUN
admet-189	178	15	.	.	PUNCT
admet-189	179	1	recently	recently	ADV
admet-189	179	2	,	,	PUNCT
admet-189	179	3	schapira	schapira	PROPN
admet-189	179	4	et	et	PROPN
admet-189	179	5	al	al	PROPN
admet-189	179	6	.	.	PROPN
admet-189	180	1	(	(	PUNCT
admet-189	180	2	2013	2013	NUM
admet-189	180	3	)	)	PUNCT
admet-189	180	4	reported	report	VERB
admet-189	180	5	the	the	DET
admet-189	180	6	dual	dual	ADJ
admet-189	180	7	action	action	NOUN
admet-189	180	8	of	of	ADP
admet-189	180	9	safinamide	safinamide	NOUN
admet-189	180	10	(	(	PUNCT
admet-189	180	11	selective	selective	ADJ
admet-189	180	12	and	and	CCONJ
admet-189	180	13	reversible	reversible	ADJ
admet-189	180	14	mao	mao	NOUN
admet-189	180	15	-	-	PUNCT
admet-189	180	16	b	b	NOUN
admet-189	180	17	inhibitors	inhibitor	NOUN
admet-189	180	18	that	that	PRON
admet-189	180	19	decrease	decrease	VERB
admet-189	180	20	glutamate	glutamate	VERB
admet-189	180	21	release	release	NOUN
admet-189	180	22	via	via	ADP
admet-189	180	23	admet	admet	PROPN
admet-189	180	24	&	&	CCONJ
admet-189	180	25	dmpk	dmpk	PROPN
admet-189	180	26	3(3	3(3	NUM
admet-189	180	27	)	)	PUNCT
admet-189	180	28	(	(	PUNCT
admet-189	180	29	2015	2015	NUM
admet-189	180	30	)	)	PUNCT
admet-189	180	31	155	155	NUM
admet-189	180	32	-	-	SYM
admet-189	180	33	181	181	NUM
admet-189	180	34	nanotechnology	nanotechnology	NOUN
admet-189	180	35	platforms	platform	NOUN
admet-189	180	36	in	in	ADP
admet-189	180	37	parkinson	parkinson	NOUN
admet-189	180	38	’s	’s	PART
admet-189	180	39	disease	disease	NOUN
admet-189	180	40	doi	doi	NOUN
admet-189	180	41	:	:	PUNCT
admet-189	180	42	10.5599	10.5599	NUM
admet-189	180	43	/	/	SYM
admet-189	180	44	admet.3.3.189	admet.3.3.189	ADP
admet-189	180	45	159	159	NUM
admet-189	180	46	blocking	blocking	NOUN
admet-189	180	47	voltage	voltage	NOUN
admet-189	180	48	depended	depend	VERB
admet-189	180	49	sodium	sodium	NOUN
admet-189	180	50	channels	channel	NOUN
admet-189	180	51	)	)	PUNCT
admet-189	180	52	by	by	ADP
admet-189	180	53	preventing	prevent	VERB
admet-189	180	54	dyskinesia	dyskinesia	NOUN
admet-189	180	55	and	and	CCONJ
admet-189	180	56	motor	motor	NOUN
admet-189	180	57	fluctuations	fluctuation	NOUN
admet-189	180	58	in	in	ADP
admet-189	180	59	early	early	ADJ
admet-189	180	60	pd	pd	PROPN
admet-189	180	61	patients	patient	NOUN
admet-189	181	1	[	[	X
admet-189	181	2	37	37	NUM
admet-189	181	3	]	]	PUNCT
admet-189	181	4	.	.	PUNCT
admet-189	182	1	further	far	ADV
admet-189	182	2	randomized	randomize	VERB
admet-189	182	3	and	and	CCONJ
admet-189	182	4	double	double	ADJ
admet-189	182	5	blind	blind	ADJ
admet-189	182	6	phase	phase	NOUN
admet-189	182	7	ii	ii	PROPN
admet-189	182	8	/	/	SYM
admet-189	182	9	iii	iii	NUM
admet-189	182	10	studies	study	NOUN
admet-189	182	11	demonstrated	demonstrate	VERB
admet-189	182	12	the	the	DET
admet-189	182	13	anti	anti	ADJ
admet-189	182	14	-	-	ADJ
admet-189	182	15	parkinson	parkinson	ADJ
admet-189	182	16	efficacy	efficacy	NOUN
admet-189	182	17	of	of	ADP
admet-189	182	18	safinamide	safinamide	NOUN
admet-189	182	19	therapy	therapy	NOUN
admet-189	182	20	in	in	ADP
admet-189	182	21	pd	pd	PROPN
admet-189	182	22	patients	patient	NOUN
admet-189	182	23	[	[	X
admet-189	182	24	38	38	NUM
admet-189	182	25	]	]	PUNCT
admet-189	182	26	.	.	PUNCT
admet-189	183	1	dopamine	dopamine	NOUN
admet-189	183	2	(	(	PUNCT
admet-189	183	3	post	post	ADJ
admet-189	183	4	-	-	ADJ
admet-189	183	5	synaptic	synaptic	ADJ
admet-189	183	6	d2	d2	NOUN
admet-189	183	7	receptors	receptor	NOUN
admet-189	183	8	)	)	PUNCT
admet-189	183	9	agonists	agonist	NOUN
admet-189	183	10	such	such	ADJ
admet-189	183	11	as	as	ADP
admet-189	183	12	non	non	ADJ
admet-189	183	13	-	-	ADJ
admet-189	183	14	ergot	ergot	ADJ
admet-189	183	15	derivatives	derivative	NOUN
admet-189	183	16	(	(	PUNCT
admet-189	183	17	pramipexole	pramipexole	NOUN
admet-189	183	18	,	,	PUNCT
admet-189	183	19	ropinirole	ropinirole	NOUN
admet-189	183	20	and	and	CCONJ
admet-189	183	21	rotigotine	rotigotine	NOUN
admet-189	183	22	)	)	PUNCT
admet-189	183	23	are	be	AUX
admet-189	183	24	also	also	ADV
admet-189	183	25	used	use	VERB
admet-189	183	26	in	in	ADP
admet-189	183	27	early	early	ADJ
admet-189	183	28	pd	pd	PROPN
admet-189	183	29	patients	patient	NOUN
admet-189	183	30	(	(	PUNCT
admet-189	183	31	above	above	ADP
admet-189	183	32	age	age	NOUN
admet-189	183	33	of	of	ADP
admet-189	183	34	60	60	NUM
admet-189	183	35	years	year	NOUN
admet-189	183	36	)	)	PUNCT
admet-189	183	37	.	.	PUNCT
admet-189	184	1	however	however	ADV
admet-189	184	2	,	,	PUNCT
admet-189	184	3	treatment	treatment	NOUN
admet-189	184	4	with	with	ADP
admet-189	184	5	dopamine	dopamine	NOUN
admet-189	184	6	agonists	agonist	NOUN
admet-189	184	7	is	be	AUX
admet-189	184	8	not	not	PART
admet-189	184	9	free	free	ADJ
admet-189	184	10	from	from	ADP
admet-189	184	11	side	side	ADJ
admet-189	184	12	effects	effect	NOUN
admet-189	184	13	like	like	ADP
admet-189	184	14	confusion	confusion	NOUN
admet-189	184	15	,	,	PUNCT
admet-189	184	16	hallucinations	hallucination	NOUN
admet-189	184	17	and	and	CCONJ
admet-189	184	18	psychosis	psychosis	NOUN
admet-189	184	19	etc	etc	X
admet-189	184	20	.	.	PUNCT
admet-189	185	1	recent	recent	ADJ
admet-189	185	2	studies	study	NOUN
admet-189	185	3	described	describe	VERB
admet-189	185	4	the	the	DET
admet-189	185	5	role	role	NOUN
admet-189	185	6	of	of	ADP
admet-189	185	7	adenosine	adenosine	ADJ
admet-189	185	8	a2a	a2a	PROPN
admet-189	185	9	receptor	receptor	NOUN
admet-189	185	10	antagonists	antagonist	NOUN
admet-189	185	11	in	in	ADP
admet-189	185	12	treatment	treatment	NOUN
admet-189	185	13	of	of	ADP
admet-189	185	14	pd	pd	PROPN
admet-189	185	15	through	through	ADP
admet-189	185	16	increased	increase	VERB
admet-189	185	17	activation	activation	NOUN
admet-189	185	18	of	of	ADP
admet-189	185	19	dopamine	dopamine	NOUN
admet-189	185	20	(	(	PUNCT
admet-189	185	21	d2	d2	NOUN
admet-189	185	22	)	)	PUNCT
admet-189	185	23	receptors	receptor	NOUN
admet-189	185	24	via	via	ADP
admet-189	185	25	inhibiting	inhibit	VERB
admet-189	185	26	adenosine	adenosine	NOUN
admet-189	185	27	receptors	receptor	NOUN
admet-189	185	28	in	in	ADP
admet-189	185	29	striatum	striatum	NOUN
admet-189	185	30	and	and	CCONJ
admet-189	185	31	basal	basal	ADJ
admet-189	185	32	ganglia	ganglia	NOUN
admet-189	185	33	nuclei	nucleus	NOUN
admet-189	185	34	.	.	PUNCT
admet-189	186	1	for	for	ADP
admet-189	186	2	instance	instance	NOUN
admet-189	186	3	,	,	PUNCT
admet-189	186	4	adenosine	adenosine	VERB
admet-189	186	5	a2a	a2a	PROPN
admet-189	186	6	receptor	receptor	NOUN
admet-189	186	7	antagonist	antagonist	NOUN
admet-189	186	8	(	(	PUNCT
admet-189	186	9	istradefylline	istradefylline	PROPN
admet-189	186	10	)	)	PUNCT
admet-189	186	11	an	an	DET
admet-189	186	12	adjuvant	adjuvant	NOUN
admet-189	186	13	with	with	ADP
admet-189	186	14	levodopa	levodopa	NOUN
admet-189	186	15	has	have	VERB
admet-189	186	16	significant	significant	ADJ
admet-189	186	17	potential	potential	NOUN
admet-189	186	18	to	to	PART
admet-189	186	19	prevent	prevent	VERB
admet-189	186	20	levodopa	levodopa	NOUN
admet-189	186	21	induced	induce	VERB
admet-189	186	22	off	off	ADP
admet-189	186	23	-	-	PUNCT
admet-189	186	24	time	time	NOUN
admet-189	186	25	fluctuation	fluctuation	NOUN
admet-189	186	26	and	and	CCONJ
admet-189	186	27	dyskinesia	dyskinesia	NOUN
admet-189	187	1	[	[	X
admet-189	187	2	39	39	NUM
admet-189	187	3	]	]	PUNCT
admet-189	187	4	.	.	PUNCT
admet-189	188	1	glutamate	glutamate	NOUN
admet-189	188	2	,	,	PUNCT
admet-189	188	3	an	an	DET
admet-189	188	4	excitatory	excitatory	ADJ
admet-189	188	5	neurotransmitter	neurotransmitter	NOUN
admet-189	188	6	in	in	ADP
admet-189	188	7	brain	brain	NOUN
admet-189	188	8	,	,	PUNCT
admet-189	188	9	has	have	VERB
admet-189	188	10	a	a	DET
admet-189	188	11	significant	significant	ADJ
admet-189	188	12	role	role	NOUN
admet-189	188	13	in	in	ADP
admet-189	188	14	pathogenesis	pathogenesis	NOUN
admet-189	188	15	of	of	ADP
admet-189	188	16	pd	pd	PROPN
admet-189	188	17	;	;	PUNCT
admet-189	188	18	hence	hence	ADV
admet-189	188	19	glutamate	glutamate	ADJ
admet-189	188	20	receptors	receptor	NOUN
admet-189	188	21	(	(	PUNCT
admet-189	188	22	subtypes	subtype	NOUN
admet-189	188	23	of	of	ADP
admet-189	188	24	glutamate	glutamate	ADJ
admet-189	188	25	receptors	receptor	NOUN
admet-189	188	26	like	like	ADP
admet-189	188	27	n	n	CCONJ
admet-189	188	28	-	-	PUNCT
admet-189	188	29	methyl	methyl	NOUN
admet-189	188	30	-	-	PUNCT
admet-189	188	31	d	d	NOUN
admet-189	188	32	-	-	ADJ
admet-189	188	33	aspartic	aspartic	ADJ
admet-189	188	34	acid	acid	NOUN
admet-189	188	35	(	(	PUNCT
admet-189	188	36	nmda	nmda	ADJ
admet-189	188	37	)	)	PUNCT
admet-189	188	38	,	,	PUNCT
admet-189	188	39	α	α	X
admet-189	188	40	-	-	PUNCT
admet-189	188	41	amino-3	amino-3	ADJ
admet-189	188	42	-	-	PUNCT
admet-189	188	43	hydroxy-5	hydroxy-5	NUM
admet-189	188	44	-	-	PUNCT
admet-189	188	45	methyl-4	methyl-4	NOUN
admet-189	188	46	-	-	PUNCT
admet-189	188	47	isoxazolepropionic	isoxazolepropionic	NOUN
admet-189	188	48	acid	acid	NOUN
admet-189	188	49	(	(	PUNCT
admet-189	188	50	ampa	ampa	NOUN
admet-189	188	51	)	)	PUNCT
admet-189	188	52	)	)	PUNCT
admet-189	188	53	antagonists	antagonist	NOUN
admet-189	188	54	can	can	AUX
admet-189	188	55	be	be	AUX
admet-189	188	56	coadministered	coadministere	VERB
admet-189	188	57	with	with	ADP
admet-189	188	58	levodopa	levodopa	NOUN
admet-189	188	59	to	to	PART
admet-189	188	60	alleviate	alleviate	VERB
admet-189	188	61	dyskinesia	dyskinesia	NOUN
admet-189	188	62	and	and	CCONJ
admet-189	188	63	other	other	ADJ
admet-189	188	64	motor	motor	NOUN
admet-189	188	65	symptoms	symptom	NOUN
admet-189	188	66	.	.	PUNCT
admet-189	189	1	recent	recent	ADJ
admet-189	189	2	clinical	clinical	ADJ
admet-189	189	3	trials	trial	NOUN
admet-189	189	4	with	with	ADP
admet-189	189	5	afq056	afq056	PROPN
admet-189	189	6	(	(	PUNCT
admet-189	189	7	mglur5	mglur5	NOUN
admet-189	189	8	i.e.	i.e.	X
admet-189	189	9	metabotropic	metabotropic	NOUN
admet-189	189	10	glutamic	glutamic	ADJ
admet-189	189	11	receptor	receptor	NOUN
admet-189	189	12	antagonist	antagonist	NOUN
admet-189	189	13	)	)	PUNCT
admet-189	189	14	demonstrated	demonstrate	VERB
admet-189	189	15	an	an	DET
admet-189	189	16	anti	anti	ADJ
admet-189	189	17	-	-	ADJ
admet-189	189	18	dyskinetic	dyskinetic	ADJ
admet-189	189	19	therapy	therapy	NOUN
admet-189	189	20	with	with	ADP
admet-189	189	21	improvement	improvement	NOUN
admet-189	189	22	in	in	ADP
admet-189	189	23	motor	motor	NOUN
admet-189	189	24	symptoms	symptom	NOUN
admet-189	189	25	.	.	PUNCT
admet-189	190	1	however	however	ADV
admet-189	190	2	,	,	PUNCT
admet-189	190	3	glutamate	glutamate	ADJ
admet-189	190	4	receptor	receptor	NOUN
admet-189	190	5	antagonists	antagonist	NOUN
admet-189	190	6	are	be	AUX
admet-189	190	7	associated	associate	VERB
admet-189	190	8	with	with	ADP
admet-189	190	9	various	various	ADJ
admet-189	190	10	side	side	NOUN
admet-189	190	11	effects	effect	NOUN
admet-189	190	12	like	like	ADP
admet-189	190	13	fatigue	fatigue	NOUN
admet-189	190	14	,	,	PUNCT
admet-189	190	15	and	and	CCONJ
admet-189	190	16	gastrointestinal	gastrointestinal	ADJ
admet-189	190	17	symptoms	symptom	NOUN
admet-189	190	18	[	[	X
admet-189	190	19	40	40	NUM
admet-189	190	20	]	]	PUNCT
admet-189	190	21	.	.	PUNCT
admet-189	191	1	different	different	ADJ
admet-189	191	2	antioxidants	antioxidant	NOUN
admet-189	191	3	(	(	PUNCT
admet-189	191	4	coenzyme	coenzyme	PROPN
admet-189	191	5	q10	q10	PROPN
admet-189	191	6	and	and	CCONJ
admet-189	191	7	n	n	CCONJ
admet-189	191	8	-	-	PUNCT
admet-189	191	9	acetyl	acetyl	NOUN
admet-189	191	10	-	-	PUNCT
admet-189	191	11	cysteine	cysteine	NOUN
admet-189	191	12	)	)	PUNCT
admet-189	191	13	that	that	PRON
admet-189	191	14	scavenge	scavenge	VERB
admet-189	191	15	reactive	reactive	ADJ
admet-189	191	16	oxygen	oxygen	NOUN
admet-189	191	17	species	specie	NOUN
admet-189	191	18	may	may	AUX
admet-189	191	19	have	have	VERB
admet-189	191	20	potential	potential	NOUN
admet-189	191	21	in	in	ADP
admet-189	191	22	preventing	prevent	VERB
admet-189	191	23	oxidative	oxidative	ADJ
admet-189	191	24	stress	stress	NOUN
admet-189	191	25	and	and	CCONJ
admet-189	191	26	dopaminergic	dopaminergic	ADJ
admet-189	191	27	neuronal	neuronal	ADJ
admet-189	191	28	degeneration	degeneration	NOUN
admet-189	191	29	in	in	ADP
admet-189	191	30	the	the	DET
admet-189	191	31	nigrostriatal	nigrostriatal	ADJ
admet-189	191	32	pathway	pathway	NOUN
admet-189	191	33	in	in	ADP
admet-189	191	34	pd	pd	PROPN
admet-189	192	1	[	[	X
admet-189	192	2	41	41	NUM
admet-189	192	3	]	]	PUNCT
admet-189	192	4	.	.	PUNCT
admet-189	193	1	neuroprotective	neuroprotective	ADJ
admet-189	193	2	therapies	therapy	NOUN
admet-189	193	3	include	include	VERB
admet-189	193	4	use	use	NOUN
admet-189	193	5	of	of	ADP
admet-189	193	6	various	various	ADJ
admet-189	193	7	neurotropic	neurotropic	ADJ
admet-189	193	8	factors	factor	NOUN
admet-189	193	9	like	like	ADP
admet-189	193	10	gdnf	gdnf	PROPN
admet-189	193	11	may	may	AUX
admet-189	193	12	induce	induce	VERB
admet-189	193	13	dopamine	dopamine	NOUN
admet-189	193	14	differentiation	differentiation	NOUN
admet-189	193	15	/	/	SYM
admet-189	193	16	regeneration	regeneration	NOUN
admet-189	193	17	,	,	PUNCT
admet-189	193	18	and	and	CCONJ
admet-189	193	19	improved	improved	ADJ
admet-189	193	20	motor	motor	NOUN
admet-189	193	21	functions	function	NOUN
admet-189	193	22	[	[	X
admet-189	193	23	42	42	NUM
admet-189	193	24	]	]	PUNCT
admet-189	193	25	.	.	PUNCT
admet-189	194	1	however	however	ADV
admet-189	194	2	,	,	PUNCT
admet-189	194	3	unsatisfactory	unsatisfactory	ADJ
admet-189	194	4	pre	pre	ADJ
admet-189	194	5	-	-	ADJ
admet-189	194	6	clinical	clinical	ADJ
admet-189	194	7	outcomes	outcome	NOUN
admet-189	194	8	were	be	AUX
admet-189	194	9	observed	observe	VERB
admet-189	194	10	since	since	SCONJ
admet-189	194	11	neurotropic	neurotropic	ADJ
admet-189	194	12	factors	factor	NOUN
admet-189	194	13	have	have	AUX
admet-189	194	14	limited	limit	VERB
admet-189	194	15	bbb	bbb	NOUN
admet-189	194	16	permeability	permeability	NOUN
admet-189	194	17	when	when	SCONJ
admet-189	194	18	administered	administer	VERB
admet-189	194	19	systemically	systemically	ADV
admet-189	194	20	.	.	PUNCT
admet-189	195	1	their	their	PRON
admet-189	195	2	direct	direct	ADJ
admet-189	195	3	administration	administration	NOUN
admet-189	195	4	through	through	ADP
admet-189	195	5	intraputaminal	intraputaminal	ADJ
admet-189	195	6	implantation	implantation	NOUN
admet-189	195	7	into	into	ADP
admet-189	195	8	basal	basal	ADJ
admet-189	195	9	ganglia	ganglia	NOUN
admet-189	195	10	has	have	AUX
admet-189	195	11	been	be	AUX
admet-189	195	12	reported	report	VERB
admet-189	195	13	in	in	ADP
admet-189	195	14	a	a	DET
admet-189	195	15	randomized	randomized	ADJ
admet-189	195	16	clinical	clinical	ADJ
admet-189	195	17	trial	trial	NOUN
admet-189	195	18	by	by	ADP
admet-189	195	19	lang	lang	PROPN
admet-189	195	20	and	and	CCONJ
admet-189	195	21	colleagues	colleague	NOUN
admet-189	195	22	[	[	X
admet-189	195	23	43	43	NUM
admet-189	195	24	]	]	PUNCT
admet-189	195	25	.	.	PUNCT
admet-189	196	1	however	however	ADV
admet-189	196	2	,	,	PUNCT
admet-189	196	3	patient	patient	NOUN
admet-189	196	4	-	-	PUNCT
admet-189	196	5	friendly	friendly	ADJ
admet-189	196	6	and	and	CCONJ
admet-189	196	7	non	non	ADJ
admet-189	196	8	-	-	ADJ
admet-189	196	9	invasive	invasive	ADJ
admet-189	196	10	approaches	approach	NOUN
admet-189	196	11	need	need	VERB
admet-189	196	12	to	to	PART
admet-189	196	13	be	be	AUX
admet-189	196	14	developed	develop	VERB
admet-189	196	15	for	for	ADP
admet-189	196	16	effective	effective	ADJ
admet-189	196	17	and	and	CCONJ
admet-189	196	18	safe	safe	ADJ
admet-189	196	19	neurotropic	neurotropic	ADJ
admet-189	196	20	therapy	therapy	NOUN
admet-189	196	21	in	in	ADP
admet-189	196	22	pd	pd	PROPN
admet-189	196	23	in	in	ADP
admet-189	196	24	the	the	DET
admet-189	196	25	future	future	NOUN
admet-189	197	1	[	[	X
admet-189	197	2	43	43	NUM
admet-189	197	3	]	]	PUNCT
admet-189	197	4	.	.	PUNCT
admet-189	198	1	neuronal	neuronal	ADJ
admet-189	198	2	signaling	signal	VERB
admet-189	198	3	in	in	ADP
admet-189	198	4	the	the	DET
admet-189	198	5	central	central	ADJ
admet-189	198	6	nervous	nervous	ADJ
admet-189	198	7	system	system	NOUN
admet-189	198	8	occurs	occur	VERB
admet-189	198	9	through	through	ADP
admet-189	198	10	a	a	DET
admet-189	198	11	combination	combination	NOUN
admet-189	198	12	of	of	ADP
admet-189	198	13	different	different	ADJ
admet-189	198	14	electrical	electrical	ADJ
admet-189	198	15	and	and	CCONJ
admet-189	198	16	chemical	chemical	NOUN
admet-189	198	17	signals	signal	NOUN
admet-189	198	18	which	which	PRON
admet-189	198	19	maintain	maintain	VERB
admet-189	198	20	the	the	DET
admet-189	198	21	homeostasis	homeostasis	NOUN
admet-189	198	22	by	by	ADP
admet-189	198	23	precise	precise	ADJ
admet-189	198	24	regulation	regulation	NOUN
admet-189	198	25	of	of	ADP
admet-189	198	26	ionic	ionic	ADJ
admet-189	198	27	composition	composition	NOUN
admet-189	198	28	across	across	ADP
admet-189	198	29	the	the	DET
admet-189	198	30	system	system	NOUN
admet-189	198	31	.	.	PUNCT
admet-189	199	1	however	however	ADV
admet-189	199	2	,	,	PUNCT
admet-189	199	3	this	this	DET
admet-189	199	4	neuronal	neuronal	ADJ
admet-189	199	5	regulation	regulation	NOUN
admet-189	199	6	is	be	AUX
admet-189	199	7	defined	define	VERB
admet-189	199	8	by	by	ADP
admet-189	199	9	presence	presence	NOUN
admet-189	199	10	of	of	ADP
admet-189	199	11	barrier	barrier	NOUN
admet-189	199	12	layers	layer	NOUN
admet-189	199	13	across	across	ADP
admet-189	199	14	the	the	DET
admet-189	199	15	system	system	NOUN
admet-189	199	16	.	.	PUNCT
admet-189	200	1	there	there	PRON
admet-189	200	2	are	be	VERB
admet-189	200	3	three	three	NUM
admet-189	200	4	different	different	ADJ
admet-189	200	5	types	type	NOUN
admet-189	200	6	of	of	ADP
admet-189	200	7	barriers	barrier	NOUN
admet-189	200	8	at	at	ADP
admet-189	200	9	the	the	DET
admet-189	200	10	interface	interface	NOUN
admet-189	200	11	of	of	ADP
admet-189	200	12	blood	blood	NOUN
admet-189	200	13	and	and	CCONJ
admet-189	200	14	the	the	DET
admet-189	200	15	central	central	ADJ
admet-189	200	16	nervous	nervous	ADJ
admet-189	200	17	system	system	NOUN
admet-189	200	18	i.e.	i.e.	X
admet-189	200	19	bloodbrain	bloodbrain	NOUN
admet-189	200	20	-	-	PUNCT
admet-189	200	21	barrier	barrier	NOUN
admet-189	200	22	(	(	PUNCT
admet-189	200	23	bbb	bbb	NOUN
admet-189	200	24	)	)	PUNCT
admet-189	200	25	,	,	PUNCT
admet-189	200	26	blood	blood	NOUN
admet-189	200	27	-	-	PUNCT
admet-189	200	28	cerebrospinal	cerebrospinal	ADJ
admet-189	200	29	fluid	fluid	NOUN
admet-189	200	30	-	-	PUNCT
admet-189	200	31	barrier	barrier	NOUN
admet-189	200	32	(	(	PUNCT
admet-189	200	33	bcsfb	bcsfb	PROPN
admet-189	200	34	)	)	PUNCT
admet-189	200	35	and	and	CCONJ
admet-189	200	36	the	the	DET
admet-189	200	37	arachnoids	arachnoid	NOUN
admet-189	200	38	barrier	barrier	NOUN
admet-189	200	39	.	.	PUNCT
admet-189	201	1	the	the	DET
admet-189	201	2	bbb	bbb	PROPN
admet-189	201	3	is	be	AUX
admet-189	201	4	widely	widely	ADV
admet-189	201	5	studied	study	VERB
admet-189	201	6	as	as	SCONJ
admet-189	201	7	it	it	PRON
admet-189	201	8	is	be	AUX
admet-189	201	9	the	the	DET
admet-189	201	10	major	major	ADJ
admet-189	201	11	limiting	limit	VERB
admet-189	201	12	factor	factor	NOUN
admet-189	201	13	for	for	ADP
admet-189	201	14	exchange	exchange	NOUN
admet-189	201	15	between	between	ADP
admet-189	201	16	blood	blood	NOUN
admet-189	201	17	and	and	CCONJ
admet-189	201	18	brain	brain	NOUN
admet-189	201	19	.	.	PUNCT
admet-189	202	1	bbb	bbb	PROPN
admet-189	202	2	with	with	ADP
admet-189	202	3	average	average	ADJ
admet-189	202	4	surface	surface	NOUN
admet-189	202	5	area	area	NOUN
admet-189	202	6	of	of	ADP
admet-189	202	7	about	about	ADP
admet-189	202	8	200cm2	200cm2	NUM
admet-189	202	9	g-1	g-1	NOUN
admet-189	202	10	is	be	AUX
admet-189	202	11	formed	form	VERB
admet-189	202	12	by	by	ADP
admet-189	202	13	the	the	DET
admet-189	202	14	brain	brain	NOUN
admet-189	202	15	microvascular	microvascular	NOUN
admet-189	202	16	capillary	capillary	ADJ
admet-189	202	17	endothelial	endothelial	NOUN
admet-189	202	18	cells	cell	NOUN
admet-189	202	19	(	(	PUNCT
admet-189	202	20	bmvec	bmvec	NOUN
admet-189	202	21	)	)	PUNCT
admet-189	202	22	comprising	comprise	VERB
admet-189	202	23	tight	tight	ADJ
admet-189	202	24	junctions	junction	NOUN
admet-189	202	25	(	(	PUNCT
admet-189	202	26	tjs	tjs	NOUN
admet-189	202	27	)	)	PUNCT
admet-189	202	28	formed	form	VERB
admet-189	202	29	by	by	ADP
admet-189	202	30	proteins	protein	NOUN
admet-189	202	31	like	like	ADP
admet-189	202	32	occludins	occludin	NOUN
admet-189	202	33	,	,	PUNCT
admet-189	202	34	claudins	claudin	NOUN
admet-189	202	35	,	,	PUNCT
admet-189	202	36	zonula	zonula	NOUN
admet-189	202	37	occludens	occluden	NOUN
admet-189	202	38	etc	etc	X
admet-189	202	39	.	.	X
admet-189	202	40	,	,	PUNCT
admet-189	202	41	adherent	adherent	ADJ
admet-189	202	42	junctions	junction	NOUN
admet-189	202	43	(	(	PUNCT
admet-189	202	44	aj	aj	ADJ
admet-189	202	45	)	)	PUNCT
admet-189	202	46	proteins	protein	NOUN
admet-189	202	47	like	like	ADP
admet-189	202	48	catenins	catenin	NOUN
admet-189	202	49	,	,	PUNCT
admet-189	202	50	cadherins	cadherin	VERB
admet-189	202	51	;	;	PUNCT
admet-189	202	52	and	and	CCONJ
admet-189	202	53	junctional	junctional	ADJ
admet-189	202	54	adhesion	adhesion	NOUN
admet-189	202	55	molecules	molecule	NOUN
admet-189	202	56	[	[	X
admet-189	202	57	44	44	NUM
admet-189	202	58	]	]	PUNCT
admet-189	202	59	,	,	PUNCT
admet-189	202	60	astrocytes	astrocyte	NOUN
admet-189	202	61	(	(	PUNCT
admet-189	202	62	bbb	bbb	NOUN
admet-189	202	63	endothelium	endothelium	NOUN
admet-189	202	64	enclosing	enclose	VERB
admet-189	202	65	glial	glial	ADJ
admet-189	202	66	cells	cell	NOUN
admet-189	202	67	)	)	PUNCT
admet-189	202	68	,	,	PUNCT
admet-189	202	69	basement	basement	NOUN
admet-189	202	70	membrane	membrane	NOUN
admet-189	202	71	and	and	CCONJ
admet-189	202	72	pericytes	pericyte	NOUN
admet-189	202	73	(	(	PUNCT
admet-189	202	74	undifferentiated	undifferentiated	ADJ
admet-189	202	75	connective	connective	ADJ
admet-189	202	76	tissue	tissue	NOUN
admet-189	202	77	cells	cell	NOUN
admet-189	202	78	that	that	PRON
admet-189	202	79	promote	promote	VERB
admet-189	202	80	proliferation	proliferation	NOUN
admet-189	202	81	,	,	PUNCT
admet-189	202	82	migration	migration	NOUN
admet-189	202	83	and	and	CCONJ
admet-189	202	84	differentiation	differentiation	NOUN
admet-189	202	85	of	of	ADP
admet-189	202	86	endothelial	endothelial	ADJ
admet-189	202	87	cells	cell	NOUN
admet-189	202	88	)	)	PUNCT
admet-189	202	89	.	.	PUNCT
admet-189	203	1	together	together	ADV
admet-189	203	2	these	these	DET
admet-189	203	3	structural	structural	ADJ
admet-189	203	4	components	component	NOUN
admet-189	203	5	play	play	VERB
admet-189	203	6	a	a	DET
admet-189	203	7	dynamic	dynamic	ADJ
admet-189	203	8	role	role	NOUN
admet-189	203	9	in	in	ADP
admet-189	203	10	maintaining	maintain	VERB
admet-189	203	11	brain	brain	NOUN
admet-189	203	12	homeostasis	homeostasis	NOUN
admet-189	203	13	,	,	PUNCT
admet-189	203	14	barrier	barrier	NOUN
admet-189	203	15	function	function	NOUN
admet-189	203	16	and	and	CCONJ
admet-189	203	17	integrity	integrity	NOUN
admet-189	203	18	of	of	ADP
admet-189	203	19	the	the	DET
admet-189	203	20	bbb	bbb	NOUN
admet-189	204	1	[	[	X
admet-189	204	2	45	45	NUM
admet-189	204	3	]	]	PUNCT
admet-189	204	4	.	.	PUNCT
admet-189	205	1	tight	tight	ADJ
admet-189	205	2	junctions	junction	NOUN
admet-189	205	3	maintain	maintain	VERB
admet-189	205	4	high	high	ADJ
admet-189	205	5	transepithelial	transepithelial	ADJ
admet-189	205	6	electrical	electrical	ADJ
admet-189	205	7	resistance	resistance	NOUN
admet-189	205	8	(	(	PUNCT
admet-189	205	9	1500	1500	NUM
admet-189	205	10	-	-	PUNCT
admet-189	205	11	2000ω	2000ω	NUM
admet-189	205	12	cm2	cm2	NOUN
admet-189	205	13	over	over	ADP
admet-189	205	14	other	other	ADJ
admet-189	205	15	peripheral	peripheral	ADJ
admet-189	205	16	microvessels	microvessel	NOUN
admet-189	205	17	)	)	PUNCT
admet-189	205	18	which	which	PRON
admet-189	205	19	shields	shield	VERB
admet-189	205	20	the	the	DET
admet-189	205	21	brain	brain	NOUN
admet-189	205	22	from	from	ADP
admet-189	205	23	different	different	ADJ
admet-189	205	24	neurotoxins	neurotoxin	NOUN
admet-189	205	25	.	.	PUNCT
admet-189	206	1	the	the	DET
admet-189	206	2	bmvec	bmvec	PROPN
admet-189	206	3	lacks	lack	VERB
admet-189	206	4	fenestrations	fenestration	NOUN
admet-189	206	5	and	and	CCONJ
admet-189	206	6	is	be	AUX
admet-189	206	7	reported	report	VERB
admet-189	206	8	to	to	PART
admet-189	206	9	have	have	VERB
admet-189	206	10	a	a	DET
admet-189	206	11	higher	high	ADJ
admet-189	206	12	mitochondrial	mitochondrial	ADJ
admet-189	206	13	load	load	NOUN
admet-189	206	14	as	as	ADP
admet-189	206	15	compared	compare	VERB
admet-189	206	16	to	to	ADP
admet-189	206	17	other	other	ADJ
admet-189	206	18	endothelial	endothelial	ADJ
admet-189	206	19	cells	cell	NOUN
admet-189	206	20	consequently	consequently	ADV
admet-189	206	21	playing	play	VERB
admet-189	206	22	an	an	DET
admet-189	206	23	important	important	ADJ
admet-189	206	24	role	role	NOUN
admet-189	206	25	in	in	ADP
admet-189	206	26	the	the	DET
admet-189	206	27	active	active	ADJ
admet-189	206	28	transport	transport	NOUN
admet-189	206	29	of	of	ADP
admet-189	206	30	nutrients	nutrient	NOUN
admet-189	206	31	to	to	ADP
admet-189	206	32	the	the	DET
admet-189	206	33	brain	brain	NOUN
admet-189	207	1	[	[	X
admet-189	207	2	46	46	NUM
admet-189	207	3	]	]	PUNCT
admet-189	207	4	.	.	PUNCT
admet-189	208	1	different	different	ADJ
admet-189	208	2	efflux	efflux	NOUN
admet-189	208	3	transporters	transporter	NOUN
admet-189	208	4	(	(	PUNCT
admet-189	208	5	p	p	NOUN
admet-189	208	6	-	-	PUNCT
admet-189	208	7	glycoprotein	glycoprotein	NOUN
admet-189	208	8	,	,	PUNCT
admet-189	208	9	multidrug	multidrug	VERB
admet-189	208	10	resistance	resistance	NOUN
admet-189	208	11	associated	associate	VERB
admet-189	208	12	proteins	protein	NOUN
admet-189	208	13	)	)	PUNCT
admet-189	208	14	,	,	PUNCT
admet-189	208	15	enzymes	enzyme	NOUN
admet-189	208	16	(	(	PUNCT
admet-189	208	17	γ	γ	X
admet-189	208	18	-	-	ADJ
admet-189	208	19	glutamyl	glutamyl	VERB
admet-189	208	20	transpeptidase	transpeptidase	NOUN
admet-189	208	21	,	,	PUNCT
admet-189	208	22	alkaline	alkaline	NOUN
admet-189	208	23	phosphatase	phosphatase	NOUN
admet-189	208	24	)	)	PUNCT
admet-189	208	25	and	and	CCONJ
admet-189	208	26	receptors	receptor	NOUN
admet-189	208	27	(	(	PUNCT
admet-189	208	28	low	low	ADJ
admet-189	208	29	density	density	NOUN
admet-189	208	30	lipoproteins	lipoprotein	NOUN
admet-189	208	31	receptor	receptor	NOUN
admet-189	208	32	,	,	PUNCT
admet-189	208	33	epidermal	epidermal	ADJ
admet-189	208	34	growth	growth	NOUN
admet-189	208	35	factor	factor	NOUN
admet-189	208	36	receptor	receptor	NOUN
admet-189	208	37	)	)	PUNCT
admet-189	208	38	are	be	AUX
admet-189	208	39	expressed	express	VERB
admet-189	208	40	on	on	ADP
admet-189	208	41	either	either	CCONJ
admet-189	208	42	luminal	luminal	ADJ
admet-189	208	43	or	or	CCONJ
admet-189	208	44	abluminal	abluminal	ADJ
admet-189	208	45	membrane	membrane	NOUN
admet-189	208	46	surfaces	surface	NOUN
admet-189	208	47	of	of	ADP
admet-189	208	48	bbb	bbb	PROPN
admet-189	208	49	to	to	PART
admet-189	208	50	prevent	prevent	VERB
admet-189	208	51	r.	r.	PROPN
admet-189	208	52	banerjee	banerjee	PROPN
admet-189	208	53	et	et	PROPN
admet-189	208	54	al	al	PROPN
admet-189	208	55	.	.	PROPN
admet-189	208	56	admet	admet	PROPN
admet-189	208	57	&	&	CCONJ
admet-189	208	58	dmpk	dmpk	PROPN
admet-189	208	59	3(3	3(3	NUM
admet-189	208	60	)	)	PUNCT
admet-189	208	61	(	(	PUNCT
admet-189	208	62	2015	2015	NUM
admet-189	208	63	)	)	PUNCT
admet-189	208	64	155	155	NUM
admet-189	208	65	-	-	SYM
admet-189	208	66	181	181	NUM
admet-189	208	67	160	160	NUM
admet-189	208	68	transport	transport	NOUN
admet-189	208	69	of	of	ADP
admet-189	208	70	substances	substance	NOUN
admet-189	208	71	across	across	ADP
admet-189	208	72	the	the	DET
admet-189	208	73	barrier	barrier	NOUN
admet-189	208	74	[	[	X
admet-189	208	75	47,48	47,48	NOUN
admet-189	208	76	]	]	X
admet-189	208	77	.	.	PUNCT
admet-189	209	1	the	the	DET
admet-189	209	2	high	high	ADJ
admet-189	209	3	electrical	electrical	ADJ
admet-189	209	4	resistance	resistance	NOUN
admet-189	209	5	of	of	ADP
admet-189	209	6	tight	tight	ADJ
admet-189	209	7	junctions	junction	NOUN
admet-189	209	8	restricts	restrict	VERB
admet-189	209	9	the	the	DET
admet-189	209	10	entry	entry	NOUN
admet-189	209	11	of	of	ADP
admet-189	209	12	macromolecules	macromolecule	NOUN
admet-189	209	13	whereas	whereas	SCONJ
admet-189	209	14	ions	ion	NOUN
admet-189	209	15	and	and	CCONJ
admet-189	209	16	other	other	ADJ
admet-189	209	17	polar	polar	ADJ
admet-189	209	18	compounds	compound	NOUN
admet-189	209	19	can	can	AUX
admet-189	209	20	only	only	ADV
admet-189	209	21	access	access	VERB
admet-189	209	22	the	the	DET
admet-189	209	23	bbb	bbb	NOUN
admet-189	209	24	via	via	ADP
admet-189	209	25	paracellular	paracellular	ADJ
admet-189	209	26	diffusion	diffusion	NOUN
admet-189	209	27	.	.	PUNCT
admet-189	210	1	there	there	PRON
admet-189	210	2	are	be	VERB
admet-189	210	3	various	various	ADJ
admet-189	210	4	specific	specific	ADJ
admet-189	210	5	and	and	CCONJ
admet-189	210	6	selective	selective	ADJ
admet-189	210	7	pathways	pathway	NOUN
admet-189	210	8	for	for	ADP
admet-189	210	9	transport	transport	NOUN
admet-189	210	10	of	of	ADP
admet-189	210	11	different	different	ADJ
admet-189	210	12	nutrient	nutrient	NOUN
admet-189	210	13	molecules	molecule	NOUN
admet-189	210	14	across	across	ADP
admet-189	210	15	bbb	bbb	PROPN
admet-189	210	16	(	(	PUNCT
admet-189	210	17	like	like	ADP
admet-189	210	18	solute	solute	NOUN
admet-189	210	19	carriers	carrier	NOUN
admet-189	210	20	,	,	PUNCT
admet-189	210	21	transporters	transporter	NOUN
admet-189	210	22	for	for	ADP
admet-189	210	23	glucose	glucose	NOUN
admet-189	210	24	,	,	PUNCT
admet-189	210	25	amino	amino	ADJ
admet-189	210	26	acids	acid	NOUN
admet-189	210	27	etc	etc	X
admet-189	210	28	.	.	X
admet-189	211	1	however	however	ADV
admet-189	211	2	,	,	PUNCT
admet-189	211	3	presence	presence	NOUN
admet-189	211	4	of	of	ADP
admet-189	211	5	efflux	efflux	ADJ
admet-189	211	6	transporters	transporter	NOUN
admet-189	211	7	like	like	ADP
admet-189	211	8	p	p	NOUN
admet-189	211	9	-	-	PUNCT
admet-189	211	10	gp	gp	NOUN
admet-189	211	11	and	and	CCONJ
admet-189	211	12	tight	tight	ADJ
admet-189	211	13	junctions	junction	NOUN
admet-189	211	14	within	within	ADP
admet-189	211	15	the	the	DET
admet-189	211	16	bbb	bbb	NOUN
admet-189	211	17	are	be	AUX
admet-189	211	18	the	the	DET
admet-189	211	19	additional	additional	ADJ
admet-189	211	20	challenges	challenge	NOUN
admet-189	211	21	for	for	ADP
admet-189	211	22	effective	effective	ADJ
admet-189	211	23	drug	drug	NOUN
admet-189	211	24	delivery	delivery	NOUN
admet-189	211	25	to	to	ADP
admet-189	211	26	the	the	DET
admet-189	211	27	cns	cns	NOUN
admet-189	212	1	[	[	X
admet-189	212	2	49,50	49,50	X
admet-189	212	3	]	]	PUNCT
admet-189	212	4	.	.	PUNCT
admet-189	213	1	standard	standard	ADJ
admet-189	213	2	pharmacotherapy	pharmacotherapy	NOUN
admet-189	213	3	for	for	ADP
admet-189	213	4	pd	pd	PROPN
admet-189	213	5	has	have	VERB
admet-189	213	6	a	a	DET
admet-189	213	7	poor	poor	ADJ
admet-189	213	8	therapeutic	therapeutic	ADJ
admet-189	213	9	efficacy	efficacy	NOUN
admet-189	213	10	,	,	PUNCT
admet-189	213	11	with	with	ADP
admet-189	213	12	only	only	ADV
admet-189	213	13	a	a	DET
admet-189	213	14	symptomatic	symptomatic	ADJ
admet-189	213	15	relief	relief	NOUN
admet-189	213	16	i.e.	i.e.	X
admet-189	213	17	they	they	PRON
admet-189	213	18	do	do	AUX
admet-189	213	19	not	not	PART
admet-189	213	20	modify	modify	VERB
admet-189	213	21	or	or	CCONJ
admet-189	213	22	identify	identify	VERB
admet-189	213	23	the	the	DET
admet-189	213	24	progress	progress	NOUN
admet-189	213	25	or	or	CCONJ
admet-189	213	26	root	root	NOUN
admet-189	213	27	cause	cause	NOUN
admet-189	213	28	of	of	ADP
admet-189	213	29	the	the	DET
admet-189	213	30	disease	disease	NOUN
admet-189	213	31	and	and	CCONJ
admet-189	213	32	show	show	VERB
admet-189	213	33	treatment	treatment	NOUN
admet-189	213	34	failure	failure	NOUN
admet-189	213	35	often	often	ADV
admet-189	213	36	associated	associate	VERB
admet-189	213	37	with	with	ADP
admet-189	213	38	various	various	ADJ
admet-189	213	39	side	side	NOUN
admet-189	213	40	effects	effect	NOUN
admet-189	213	41	.	.	PUNCT
admet-189	214	1	the	the	DET
admet-189	214	2	limitations	limitation	NOUN
admet-189	214	3	of	of	ADP
admet-189	214	4	current	current	ADJ
admet-189	214	5	therapeutic	therapeutic	ADJ
admet-189	214	6	modalities	modality	NOUN
admet-189	214	7	,	,	PUNCT
admet-189	214	8	as	as	SCONJ
admet-189	214	9	outlined	outline	VERB
admet-189	214	10	in	in	ADP
admet-189	214	11	fig	fig	NOUN
admet-189	214	12	.	.	PUNCT
admet-189	215	1	1	1	NUM
admet-189	215	2	need	need	VERB
admet-189	215	3	to	to	PART
admet-189	215	4	be	be	AUX
admet-189	215	5	addressed	address	VERB
admet-189	215	6	for	for	ADP
admet-189	215	7	the	the	DET
admet-189	215	8	appropriate	appropriate	ADJ
admet-189	215	9	treatment	treatment	NOUN
admet-189	215	10	of	of	ADP
admet-189	215	11	pd	pd	PROPN
admet-189	215	12	.	.	PROPN
admet-189	215	13	figure	figure	NOUN
admet-189	215	14	1	1	NUM
admet-189	215	15	.	.	PUNCT
admet-189	215	16	limitations	limitation	NOUN
admet-189	215	17	in	in	ADP
admet-189	215	18	the	the	DET
admet-189	215	19	treatment	treatment	NOUN
admet-189	215	20	of	of	ADP
admet-189	215	21	parkinson	parkinson	NOUN
admet-189	215	22	’s	’s	PART
admet-189	215	23	disease	disease	NOUN
admet-189	215	24	neurostimulation	neurostimulation	NOUN
admet-189	215	25	by	by	ADP
admet-189	215	26	surgical	surgical	ADJ
admet-189	215	27	approaches	approach	NOUN
admet-189	215	28	different	different	ADJ
admet-189	215	29	surgical	surgical	ADJ
admet-189	215	30	approaches	approach	NOUN
admet-189	215	31	have	have	AUX
admet-189	215	32	been	be	AUX
admet-189	215	33	under	under	ADP
admet-189	215	34	clinical	clinical	ADJ
admet-189	215	35	practices	practice	NOUN
admet-189	215	36	for	for	ADP
admet-189	215	37	the	the	DET
admet-189	215	38	management	management	NOUN
admet-189	215	39	of	of	ADP
admet-189	215	40	pd	pd	PROPN
admet-189	215	41	.	.	PROPN
admet-189	216	1	deep	deep	ADJ
admet-189	216	2	brain	brain	NOUN
admet-189	216	3	stimulation	stimulation	NOUN
admet-189	216	4	is	be	AUX
admet-189	216	5	one	one	NUM
admet-189	216	6	of	of	ADP
admet-189	216	7	the	the	DET
admet-189	216	8	surgical	surgical	ADJ
admet-189	216	9	approaches	approach	NOUN
admet-189	216	10	that	that	PRON
admet-189	216	11	involve	involve	VERB
admet-189	216	12	implantation	implantation	NOUN
admet-189	216	13	of	of	ADP
admet-189	216	14	ct	ct	PROPN
admet-189	216	15	/	/	SYM
admet-189	216	16	mri	mri	NOUN
admet-189	216	17	guided	guide	VERB
admet-189	216	18	electrodes	electrode	NOUN
admet-189	216	19	in	in	ADP
admet-189	216	20	the	the	DET
admet-189	216	21	subthalamic	subthalamic	ADJ
admet-189	216	22	nucleus	nucleus	NOUN
admet-189	216	23	or	or	CCONJ
admet-189	216	24	in	in	ADP
admet-189	216	25	the	the	DET
admet-189	216	26	globus	globus	ADJ
admet-189	216	27	pallidus	pallidus	NOUN
admet-189	216	28	.	.	PUNCT
admet-189	217	1	the	the	DET
admet-189	217	2	impulse	impulse	ADJ
admet-189	217	3	generator	generator	NOUN
admet-189	217	4	creates	create	VERB
admet-189	217	5	electrical	electrical	ADJ
admet-189	217	6	stimulation	stimulation	NOUN
admet-189	217	7	affecting	affect	VERB
admet-189	217	8	the	the	DET
admet-189	217	9	firing	firing	NOUN
admet-189	217	10	pattern	pattern	NOUN
admet-189	217	11	of	of	ADP
admet-189	217	12	neurons	neuron	NOUN
admet-189	217	13	in	in	ADP
admet-189	217	14	the	the	DET
admet-189	217	15	implanted	implant	VERB
admet-189	217	16	area	area	NOUN
admet-189	217	17	along	along	ADP
admet-189	217	18	with	with	ADP
admet-189	217	19	the	the	DET
admet-189	217	20	release	release	NOUN
admet-189	217	21	of	of	ADP
admet-189	217	22	neurotransmitters	neurotransmitter	NOUN
admet-189	217	23	glutamate	glutamate	VERB
admet-189	217	24	and	and	CCONJ
admet-189	217	25	adenosine	adenosine	VERB
admet-189	217	26	and	and	CCONJ
admet-189	217	27	improves	improve	VERB
admet-189	217	28	the	the	DET
admet-189	217	29	motor	motor	NOUN
admet-189	217	30	symptoms	symptom	NOUN
admet-189	217	31	in	in	ADP
admet-189	217	32	pd	pd	PROPN
admet-189	217	33	with	with	ADP
admet-189	217	34	neurogenesis	neurogenesis	NOUN
admet-189	217	35	in	in	ADP
admet-189	217	36	addition	addition	NOUN
admet-189	217	37	to	to	ADP
admet-189	217	38	causing	cause	VERB
admet-189	217	39	an	an	DET
admet-189	217	40	increased	increase	VERB
admet-189	217	41	blood	blood	NOUN
admet-189	217	42	circulation	circulation	NOUN
admet-189	217	43	in	in	ADP
admet-189	217	44	the	the	DET
admet-189	217	45	stimulated	stimulated	ADJ
admet-189	217	46	regions	region	NOUN
admet-189	217	47	[	[	X
admet-189	217	48	51	51	NUM
admet-189	217	49	]	]	PUNCT
admet-189	217	50	.	.	PUNCT
admet-189	218	1	several	several	ADJ
admet-189	218	2	studies	study	NOUN
admet-189	218	3	have	have	AUX
admet-189	218	4	reported	report	VERB
admet-189	218	5	that	that	SCONJ
admet-189	218	6	deep	deep	ADJ
admet-189	218	7	brain	brain	NOUN
admet-189	218	8	stimulation	stimulation	NOUN
admet-189	218	9	as	as	ADP
admet-189	218	10	an	an	DET
admet-189	218	11	adjuvant	adjuvant	NOUN
admet-189	218	12	with	with	ADP
admet-189	218	13	pharmacotherapy	pharmacotherapy	NOUN
admet-189	218	14	showed	show	VERB
admet-189	218	15	significant	significant	ADJ
admet-189	218	16	improvements	improvement	NOUN
admet-189	218	17	in	in	ADP
admet-189	218	18	patient	patient	ADJ
admet-189	218	19	daily	daily	ADJ
admet-189	218	20	activities	activity	NOUN
admet-189	218	21	and	and	CCONJ
admet-189	218	22	quality	quality	NOUN
admet-189	218	23	of	of	ADP
admet-189	218	24	life	life	NOUN
admet-189	218	25	by	by	ADP
admet-189	218	26	reducing	reduce	VERB
admet-189	218	27	motor	motor	NOUN
admet-189	218	28	disability	disability	NOUN
admet-189	218	29	,	,	PUNCT
admet-189	218	30	levodopa	levodopa	NOUN
admet-189	218	31	induced	induce	VERB
admet-189	218	32	motor	motor	NOUN
admet-189	218	33	fluctuations	fluctuation	NOUN
admet-189	218	34	[	[	X
admet-189	218	35	52	52	NUM
admet-189	218	36	]	]	PUNCT
admet-189	218	37	.	.	PUNCT
admet-189	219	1	however	however	ADV
admet-189	219	2	,	,	PUNCT
admet-189	219	3	it	it	PRON
admet-189	219	4	is	be	AUX
admet-189	219	5	often	often	ADV
admet-189	219	6	associated	associate	VERB
admet-189	219	7	with	with	ADP
admet-189	219	8	many	many	ADJ
admet-189	219	9	adverse	adverse	ADJ
admet-189	219	10	effects	effect	NOUN
admet-189	219	11	like	like	ADP
admet-189	219	12	intracranial	intracranial	ADJ
admet-189	219	13	hemorrhage	hemorrhage	NOUN
admet-189	219	14	,	,	PUNCT
admet-189	219	15	cognitive	cognitive	ADJ
admet-189	219	16	impairment	impairment	NOUN
admet-189	219	17	,	,	PUNCT
admet-189	219	18	anxiety	anxiety	NOUN
admet-189	219	19	,	,	PUNCT
admet-189	219	20	infection	infection	NOUN
admet-189	219	21	and	and	CCONJ
admet-189	219	22	post	post	ADJ
admet-189	219	23	-	-	ADJ
admet-189	219	24	operative	operative	ADJ
admet-189	219	25	seizures	seizure	NOUN
admet-189	219	26	.	.	PUNCT
admet-189	220	1	[	[	X
admet-189	220	2	53,54	53,54	NUM
admet-189	220	3	]	]	X
admet-189	220	4	.	.	PUNCT
admet-189	221	1	thalamotomy	thalamotomy	NOUN
admet-189	221	2	,	,	PUNCT
admet-189	221	3	is	be	AUX
admet-189	221	4	an	an	DET
admet-189	221	5	invasive	invasive	ADJ
admet-189	221	6	approach	approach	NOUN
admet-189	221	7	performed	perform	VERB
admet-189	221	8	using	use	VERB
admet-189	221	9	a	a	DET
admet-189	221	10	probe	probe	NOUN
admet-189	221	11	in	in	ADP
admet-189	221	12	region	region	NOUN
admet-189	221	13	contralateral	contralateral	ADJ
admet-189	221	14	to	to	ADP
admet-189	221	15	the	the	DET
admet-189	221	16	tremor	tremor	NOUN
admet-189	221	17	and	and	CCONJ
admet-189	221	18	lesion	lesion	NOUN
admet-189	221	19	in	in	ADP
admet-189	221	20	severe	severe	ADJ
admet-189	221	21	pd	pd	PROPN
admet-189	221	22	cases	case	NOUN
admet-189	221	23	.	.	PUNCT
admet-189	222	1	recently	recently	ADV
admet-189	222	2	transcranial	transcranial	ADJ
admet-189	222	3	mri	mri	NOUN
admet-189	222	4	guided	guide	VERB
admet-189	222	5	focus	focus	NOUN
admet-189	222	6	ultrasound	ultrasound	NOUN
admet-189	222	7	technology	technology	NOUN
admet-189	222	8	was	be	AUX
admet-189	222	9	use	use	NOUN
admet-189	222	10	to	to	PART
admet-189	222	11	perform	perform	VERB
admet-189	222	12	thalamotomy	thalamotomy	NOUN
admet-189	222	13	which	which	PRON
admet-189	222	14	significantly	significantly	ADV
admet-189	222	15	reduced	reduce	VERB
admet-189	222	16	tremor	tremor	NOUN
admet-189	222	17	,	,	PUNCT
admet-189	222	18	postural	postural	ADJ
admet-189	222	19	disability	disability	NOUN
admet-189	222	20	and	and	CCONJ
admet-189	222	21	improved	improve	VERB
admet-189	222	22	the	the	DET
admet-189	222	23	quality	quality	NOUN
admet-189	222	24	of	of	ADP
admet-189	222	25	life	life	NOUN
admet-189	222	26	over	over	ADP
admet-189	222	27	a	a	DET
admet-189	222	28	period	period	NOUN
admet-189	222	29	of	of	ADP
admet-189	222	30	one	one	NUM
admet-189	222	31	year	year	NOUN
admet-189	222	32	posttreatment	posttreatment	NOUN
admet-189	222	33	.	.	PUNCT
admet-189	223	1	however	however	ADV
admet-189	223	2	,	,	PUNCT
admet-189	223	3	side	side	ADJ
admet-189	223	4	effects	effect	NOUN
admet-189	223	5	include	include	VERB
admet-189	223	6	cognitive	cognitive	ADJ
admet-189	223	7	impairment	impairment	NOUN
admet-189	223	8	,	,	PUNCT
admet-189	223	9	paresthesia	paresthesia	NOUN
admet-189	223	10	of	of	ADP
admet-189	223	11	tongue	tongue	NOUN
admet-189	223	12	and	and	CCONJ
admet-189	223	13	figure	figure	NOUN
admet-189	223	14	,	,	PUNCT
admet-189	223	15	headache	headache	NOUN
admet-189	223	16	and	and	CCONJ
admet-189	223	17	nausea	nausea	NOUN
admet-189	224	1	[	[	X
admet-189	224	2	55	55	NUM
admet-189	224	3	]	]	PUNCT
admet-189	224	4	.	.	PUNCT
admet-189	225	1	gamma	gamma	PROPN
admet-189	225	2	knife	knife	PROPN
admet-189	225	3	(	(	PUNCT
admet-189	225	4	gk	gk	PROPN
admet-189	225	5	)	)	PUNCT
admet-189	225	6	is	be	AUX
admet-189	225	7	another	another	DET
admet-189	225	8	non	non	ADJ
admet-189	225	9	-	-	ADJ
admet-189	225	10	invasive	invasive	ADJ
admet-189	225	11	surgical	surgical	ADJ
admet-189	225	12	procedure	procedure	NOUN
admet-189	225	13	where	where	SCONJ
admet-189	225	14	the	the	DET
admet-189	225	15	emitted	emitted	ADJ
admet-189	225	16	gamma	gamma	NOUN
admet-189	225	17	admet	admet	PROPN
admet-189	225	18	&	&	CCONJ
admet-189	225	19	dmpk	dmpk	PROPN
admet-189	225	20	3(3	3(3	NUM
admet-189	225	21	)	)	PUNCT
admet-189	225	22	(	(	PUNCT
admet-189	225	23	2015	2015	NUM
admet-189	225	24	)	)	PUNCT
admet-189	225	25	155	155	NUM
admet-189	225	26	-	-	SYM
admet-189	225	27	181	181	NUM
admet-189	225	28	nanotechnology	nanotechnology	NOUN
admet-189	225	29	platforms	platform	NOUN
admet-189	225	30	in	in	ADP
admet-189	225	31	parkinson	parkinson	NOUN
admet-189	225	32	’s	’s	PART
admet-189	225	33	disease	disease	NOUN
admet-189	225	34	doi	doi	NOUN
admet-189	225	35	:	:	PUNCT
admet-189	225	36	10.5599	10.5599	NUM
admet-189	225	37	/	/	SYM
admet-189	225	38	admet.3.3.189	admet.3.3.189	ADP
admet-189	225	39	161	161	NUM
admet-189	225	40	radiations	radiation	NOUN
admet-189	225	41	intersect	intersect	ADJ
admet-189	225	42	within	within	ADP
admet-189	225	43	the	the	DET
admet-189	225	44	target	target	NOUN
admet-189	225	45	brain	brain	NOUN
admet-189	225	46	region	region	NOUN
admet-189	225	47	within	within	ADP
admet-189	225	48	15	15	NUM
admet-189	225	49	-	-	PUNCT
admet-189	225	50	30min	30min	NOUN
admet-189	225	51	under	under	ADP
admet-189	225	52	anesthesia	anesthesia	NOUN
admet-189	225	53	and	and	CCONJ
admet-189	225	54	led	lead	VERB
admet-189	225	55	to	to	ADP
admet-189	225	56	a	a	DET
admet-189	225	57	significant	significant	ADJ
admet-189	225	58	improvement	improvement	NOUN
admet-189	225	59	in	in	ADP
admet-189	225	60	tremor	tremor	NOUN
admet-189	225	61	and	and	CCONJ
admet-189	225	62	daily	daily	ADJ
admet-189	225	63	activities	activity	NOUN
admet-189	225	64	after	after	ADP
admet-189	225	65	several	several	ADJ
admet-189	225	66	months	month	NOUN
admet-189	225	67	of	of	ADP
admet-189	225	68	treatment	treatment	NOUN
admet-189	225	69	.	.	PUNCT
admet-189	226	1	however	however	ADV
admet-189	226	2	,	,	PUNCT
admet-189	226	3	gk	gk	NOUN
admet-189	226	4	procedure	procedure	NOUN
admet-189	226	5	suffers	suffer	VERB
admet-189	226	6	from	from	ADP
admet-189	226	7	lack	lack	NOUN
admet-189	226	8	of	of	ADP
admet-189	226	9	target	target	NOUN
admet-189	226	10	region	region	NOUN
admet-189	226	11	accuracy	accuracy	NOUN
admet-189	226	12	hence	hence	ADV
admet-189	226	13	demands	demand	VERB
admet-189	226	14	guided	guide	VERB
admet-189	226	15	assist	assist	NOUN
admet-189	226	16	for	for	ADP
admet-189	226	17	more	more	ADV
admet-189	226	18	precise	precise	ADJ
admet-189	226	19	neurostimulation	neurostimulation	NOUN
admet-189	226	20	against	against	ADP
admet-189	226	21	pd	pd	PROPN
admet-189	227	1	[	[	X
admet-189	227	2	56	56	NUM
admet-189	227	3	]	]	PUNCT
admet-189	227	4	.	.	PUNCT
admet-189	228	1	nanotechnology	nanotechnology	NOUN
admet-189	228	2	as	as	ADP
admet-189	228	3	a	a	DET
admet-189	228	4	viable	viable	ADJ
admet-189	228	5	alternative	alternative	ADJ
admet-189	228	6	nanotechnology	nanotechnology	NOUN
admet-189	228	7	and	and	CCONJ
admet-189	228	8	nanoscience	nanoscience	NOUN
admet-189	228	9	are	be	AUX
admet-189	228	10	the	the	DET
admet-189	228	11	interdisciplinary	interdisciplinary	ADJ
admet-189	228	12	areas	area	NOUN
admet-189	228	13	involving	involve	VERB
admet-189	228	14	the	the	DET
admet-189	228	15	development	development	NOUN
admet-189	228	16	of	of	ADP
admet-189	228	17	nanosized	nanosized	ADJ
admet-189	228	18	materials	material	NOUN
admet-189	228	19	.	.	PUNCT
admet-189	229	1	the	the	DET
admet-189	229	2	foundations	foundation	NOUN
admet-189	229	3	of	of	ADP
admet-189	229	4	these	these	DET
admet-189	229	5	areas	area	NOUN
admet-189	229	6	and	and	CCONJ
admet-189	229	7	the	the	DET
admet-189	229	8	concept	concept	NOUN
admet-189	229	9	of	of	ADP
admet-189	229	10	miniaturization	miniaturization	NOUN
admet-189	229	11	involved	involve	VERB
admet-189	229	12	were	be	AUX
admet-189	229	13	introduced	introduce	VERB
admet-189	229	14	by	by	ADP
admet-189	229	15	richard	richard	PROPN
admet-189	229	16	feynman	feynman	PROPN
admet-189	229	17	half	half	DET
admet-189	229	18	a	a	DET
admet-189	229	19	century	century	NOUN
admet-189	229	20	ago	ago	ADV
admet-189	229	21	in	in	ADP
admet-189	229	22	his	his	PRON
admet-189	229	23	renowned	renowned	ADJ
admet-189	229	24	talk	talk	NOUN
admet-189	229	25	titled	title	VERB
admet-189	229	26	:	:	PUNCT
admet-189	229	27	“	"	PUNCT
admet-189	229	28	there	there	PRON
admet-189	229	29	's	be	VERB
admet-189	229	30	plenty	plenty	NOUN
admet-189	229	31	of	of	ADP
admet-189	229	32	room	room	NOUN
admet-189	229	33	at	at	ADP
admet-189	229	34	the	the	DET
admet-189	229	35	bottom	bottom	NOUN
admet-189	229	36	.	.	PUNCT
admet-189	229	37	”	"	PUNCT
admet-189	230	1	[	[	X
admet-189	230	2	58	58	NUM
admet-189	230	3	]	]	PUNCT
admet-189	230	4	.	.	PUNCT
admet-189	231	1	principally	principally	ADV
admet-189	231	2	,	,	PUNCT
admet-189	231	3	nanoscience	nanoscience	PROPN
admet-189	231	4	is	be	AUX
admet-189	231	5	directed	direct	VERB
admet-189	231	6	toward	toward	ADP
admet-189	231	7	manipulation	manipulation	NOUN
admet-189	231	8	of	of	ADP
admet-189	231	9	materials	material	NOUN
admet-189	231	10	at	at	ADP
admet-189	231	11	atomic	atomic	ADJ
admet-189	231	12	or	or	CCONJ
admet-189	231	13	subatomic	subatomic	ADJ
admet-189	231	14	levels	level	NOUN
admet-189	231	15	whose	whose	DET
admet-189	231	16	properties	property	NOUN
admet-189	231	17	differ	differ	VERB
admet-189	231	18	significantly	significantly	ADV
admet-189	231	19	from	from	ADP
admet-189	231	20	those	those	PRON
admet-189	231	21	of	of	ADP
admet-189	231	22	bulk	bulk	ADJ
admet-189	231	23	matter	matter	NOUN
admet-189	231	24	whereas	whereas	SCONJ
admet-189	231	25	nanotechnology	nanotechnology	NOUN
admet-189	231	26	aims	aim	VERB
admet-189	231	27	to	to	PART
admet-189	231	28	exploit	exploit	VERB
admet-189	231	29	such	such	ADJ
admet-189	231	30	manipulated	manipulate	VERB
admet-189	231	31	materials	material	NOUN
admet-189	231	32	for	for	ADP
admet-189	231	33	designing	designing	NOUN
admet-189	231	34	,	,	PUNCT
admet-189	231	35	characterizing	characterizing	NOUN
admet-189	231	36	,	,	PUNCT
admet-189	231	37	and	and	CCONJ
admet-189	231	38	production	production	NOUN
admet-189	231	39	of	of	ADP
admet-189	231	40	improved	improved	ADJ
admet-189	231	41	structure	structure	NOUN
admet-189	231	42	,	,	PUNCT
admet-189	231	43	devices	device	NOUN
admet-189	231	44	and	and	CCONJ
admet-189	231	45	systems	system	NOUN
admet-189	231	46	with	with	ADP
admet-189	231	47	controlled	control	VERB
admet-189	231	48	size	size	NOUN
admet-189	231	49	and	and	CCONJ
admet-189	231	50	shape	shape	NOUN
admet-189	231	51	(	(	PUNCT
admet-189	231	52	1	1	NUM
admet-189	231	53	-	-	SYM
admet-189	231	54	100	100	NUM
admet-189	231	55	nm	nm	NOUN
admet-189	231	56	)	)	PUNCT
admet-189	231	57	for	for	ADP
admet-189	231	58	various	various	ADJ
admet-189	231	59	applications	application	NOUN
admet-189	231	60	[	[	X
admet-189	231	61	57	57	NUM
admet-189	231	62	]	]	PUNCT
admet-189	231	63	.	.	PUNCT
admet-189	232	1	nanotechnology	nanotechnology	PROPN
admet-189	232	2	has	have	AUX
admet-189	232	3	found	find	VERB
admet-189	232	4	numerous	numerous	ADJ
admet-189	232	5	applications	application	NOUN
admet-189	232	6	in	in	ADP
admet-189	232	7	biomedical	biomedical	ADJ
admet-189	232	8	sciences	science	NOUN
admet-189	232	9	referred	refer	VERB
admet-189	232	10	to	to	ADP
admet-189	232	11	as	as	ADP
admet-189	232	12	nanomedicine	nanomedicine	ADJ
admet-189	232	13	.	.	PUNCT
admet-189	233	1	for	for	ADP
admet-189	233	2	the	the	DET
admet-189	233	3	purposes	purpose	NOUN
admet-189	233	4	of	of	ADP
admet-189	233	5	nanomedicine	nanomedicine	NOUN
admet-189	233	6	,	,	PUNCT
admet-189	233	7	the	the	DET
admet-189	233	8	definition	definition	NOUN
admet-189	233	9	of	of	ADP
admet-189	233	10	a	a	DET
admet-189	233	11	nanomaterial	nanomaterial	NOUN
admet-189	233	12	is	be	AUX
admet-189	233	13	not	not	PART
admet-189	233	14	restricted	restrict	VERB
admet-189	233	15	to	to	ADP
admet-189	233	16	those	those	PRON
admet-189	233	17	below	below	ADP
admet-189	233	18	100	100	NUM
admet-189	233	19	nm	nm	NOUN
admet-189	233	20	in	in	ADP
admet-189	233	21	size	size	NOUN
admet-189	233	22	but	but	CCONJ
admet-189	233	23	extend	extend	VERB
admet-189	233	24	to	to	ADP
admet-189	233	25	various	various	ADJ
admet-189	233	26	submicron	submicron	NOUN
admet-189	233	27	sized	size	VERB
admet-189	233	28	materials	material	NOUN
admet-189	233	29	.	.	PUNCT
admet-189	234	1	the	the	DET
admet-189	234	2	key	key	ADJ
admet-189	234	3	aspect	aspect	NOUN
admet-189	234	4	is	be	AUX
admet-189	234	5	to	to	PART
admet-189	234	6	exploit	exploit	VERB
admet-189	234	7	the	the	DET
admet-189	234	8	size	size	NOUN
admet-189	234	9	dependant	dependant	ADJ
admet-189	234	10	change	change	NOUN
admet-189	234	11	in	in	ADP
admet-189	234	12	properties	property	NOUN
admet-189	234	13	of	of	ADP
admet-189	234	14	submicron	submicron	NOUN
admet-189	234	15	sized	size	VERB
admet-189	234	16	materials	material	NOUN
admet-189	234	17	that	that	PRON
admet-189	234	18	can	can	AUX
admet-189	234	19	be	be	AUX
admet-189	234	20	exploited	exploit	VERB
admet-189	234	21	for	for	ADP
admet-189	234	22	altered	altered	ADJ
admet-189	234	23	cellular	cellular	ADJ
admet-189	234	24	responses	response	NOUN
admet-189	234	25	.	.	PUNCT
admet-189	235	1	nanostructures	nanostructure	NOUN
admet-189	235	2	have	have	AUX
admet-189	235	3	been	be	AUX
admet-189	235	4	applied	apply	VERB
admet-189	235	5	for	for	ADP
admet-189	235	6	diagnosis	diagnosis	NOUN
admet-189	235	7	of	of	ADP
admet-189	235	8	diseases	disease	NOUN
admet-189	235	9	,	,	PUNCT
admet-189	235	10	imaging	imaging	NOUN
admet-189	235	11	,	,	PUNCT
admet-189	235	12	as	as	ADP
admet-189	235	13	devices	device	NOUN
admet-189	235	14	,	,	PUNCT
admet-189	235	15	for	for	ADP
admet-189	235	16	tissue	tissue	NOUN
admet-189	235	17	regeneration	regeneration	NOUN
admet-189	235	18	as	as	ADV
admet-189	235	19	well	well	ADV
admet-189	235	20	as	as	ADP
admet-189	235	21	for	for	ADP
admet-189	235	22	drug	drug	NOUN
admet-189	235	23	delivery	delivery	NOUN
admet-189	235	24	and	and	CCONJ
admet-189	235	25	therapeutics	therapeutic	NOUN
admet-189	235	26	.	.	PUNCT
admet-189	236	1	nanotechnology	nanotechnology	NOUN
admet-189	236	2	which	which	PRON
admet-189	236	3	involves	involve	VERB
admet-189	236	4	the	the	DET
admet-189	236	5	manipulation	manipulation	NOUN
admet-189	236	6	of	of	ADP
admet-189	236	7	various	various	ADJ
admet-189	236	8	systems	system	NOUN
admet-189	236	9	at	at	ADP
admet-189	236	10	the	the	DET
admet-189	236	11	nanoscale	nanoscale	NOUN
admet-189	236	12	can	can	AUX
admet-189	236	13	have	have	VERB
admet-189	236	14	potential	potential	NOUN
admet-189	236	15	in	in	ADP
admet-189	236	16	the	the	DET
admet-189	236	17	management	management	NOUN
admet-189	236	18	of	of	ADP
admet-189	236	19	parkinson	parkinson	NOUN
admet-189	236	20	’s	’s	PART
admet-189	236	21	disease	disease	NOUN
admet-189	236	22	.	.	PUNCT
admet-189	237	1	a	a	DET
admet-189	237	2	few	few	ADJ
admet-189	237	3	advantages	advantage	NOUN
admet-189	237	4	of	of	ADP
admet-189	237	5	nanotechnology	nanotechnology	NOUN
admet-189	237	6	platforms	platform	NOUN
admet-189	237	7	in	in	ADP
admet-189	237	8	pd	pd	PROPN
admet-189	237	9	are	be	AUX
admet-189	237	10	enlisted	enlist	VERB
admet-189	237	11	below	below	ADP
admet-189	237	12	:	:	PUNCT
admet-189	237	13	1	1	X
admet-189	237	14	.	.	X
admet-189	237	15	nanotechnology	nanotechnology	NOUN
admet-189	237	16	can	can	AUX
admet-189	237	17	help	help	VERB
admet-189	237	18	in	in	ADP
admet-189	237	19	the	the	DET
admet-189	237	20	development	development	NOUN
admet-189	237	21	of	of	ADP
admet-189	237	22	sensors	sensor	NOUN
admet-189	237	23	that	that	PRON
admet-189	237	24	are	be	AUX
admet-189	237	25	able	able	ADJ
admet-189	237	26	to	to	PART
admet-189	237	27	sense	sense	VERB
admet-189	237	28	various	various	ADJ
admet-189	237	29	biomarkers	biomarker	NOUN
admet-189	237	30	at	at	ADP
admet-189	237	31	low	low	ADJ
admet-189	237	32	concentrations	concentration	NOUN
admet-189	237	33	in	in	ADP
admet-189	237	34	the	the	DET
admet-189	237	35	presence	presence	NOUN
admet-189	237	36	of	of	ADP
admet-189	237	37	other	other	ADJ
admet-189	237	38	analytes	analyte	NOUN
admet-189	237	39	and	and	CCONJ
admet-189	237	40	help	help	VERB
admet-189	237	41	in	in	ADP
admet-189	237	42	the	the	DET
admet-189	237	43	development	development	NOUN
admet-189	237	44	of	of	ADP
admet-189	237	45	affordable	affordable	ADJ
admet-189	237	46	diagnostic	diagnostic	ADJ
admet-189	237	47	devices	device	NOUN
admet-189	237	48	.	.	PUNCT
admet-189	238	1	2	2	X
admet-189	238	2	.	.	X
admet-189	238	3	nanotechnology	nanotechnology	NOUN
admet-189	238	4	-	-	PUNCT
admet-189	238	5	based	base	VERB
admet-189	238	6	drug	drug	NOUN
admet-189	238	7	delivery	delivery	NOUN
admet-189	238	8	platforms	platform	NOUN
admet-189	238	9	play	play	VERB
admet-189	238	10	an	an	DET
admet-189	238	11	important	important	ADJ
admet-189	238	12	role	role	NOUN
admet-189	238	13	to	to	PART
admet-189	238	14	achieve	achieve	VERB
admet-189	238	15	better	well	ADJ
admet-189	238	16	therapeutic	therapeutic	ADJ
admet-189	238	17	efficacy	efficacy	NOUN
admet-189	238	18	and	and	CCONJ
admet-189	238	19	enhance	enhance	VERB
admet-189	238	20	bioavailability	bioavailability	NOUN
admet-189	238	21	across	across	ADP
admet-189	238	22	bbb	bbb	PROPN
admet-189	238	23	for	for	ADP
admet-189	238	24	the	the	DET
admet-189	238	25	treatment	treatment	NOUN
admet-189	238	26	of	of	ADP
admet-189	238	27	cns	cns	NOUN
admet-189	238	28	disorders	disorder	NOUN
admet-189	238	29	.	.	PUNCT
admet-189	239	1	the	the	DET
admet-189	239	2	different	different	ADJ
admet-189	239	3	platforms	platform	NOUN
admet-189	239	4	like	like	ADP
admet-189	239	5	active	active	ADJ
admet-189	239	6	targeting	targeting	NOUN
admet-189	239	7	using	use	VERB
admet-189	239	8	receptor	receptor	NOUN
admet-189	239	9	mediated	mediate	VERB
admet-189	239	10	endoor	endoor	ADJ
admet-189	239	11	transcytosis	transcytosis	NOUN
admet-189	239	12	,	,	PUNCT
admet-189	239	13	stimuli	stimuli	VERB
admet-189	239	14	responsive	responsive	ADJ
admet-189	239	15	nano	nano	NOUN
admet-189	239	16	-	-	PUNCT
admet-189	239	17	carriers	carrier	NOUN
admet-189	239	18	and	and	CCONJ
admet-189	239	19	macrophage	macrophage	ADJ
admet-189	239	20	mediated	mediate	VERB
admet-189	239	21	passive	passive	ADJ
admet-189	239	22	targeting	targeting	NOUN
admet-189	239	23	etc	etc	X
admet-189	239	24	.	.	X
admet-189	239	25	are	be	AUX
admet-189	239	26	few	few	ADJ
admet-189	239	27	of	of	ADP
admet-189	239	28	the	the	DET
admet-189	239	29	approaches	approach	NOUN
admet-189	239	30	that	that	PRON
admet-189	239	31	can	can	AUX
admet-189	239	32	improve	improve	VERB
admet-189	239	33	the	the	DET
admet-189	239	34	treatment	treatment	NOUN
admet-189	239	35	of	of	ADP
admet-189	239	36	pd	pd	PROPN
admet-189	239	37	.	.	PROPN
admet-189	240	1	3	3	X
admet-189	240	2	.	.	X
admet-189	240	3	nanotechnology	nanotechnology	NOUN
admet-189	240	4	can	can	AUX
admet-189	240	5	also	also	ADV
admet-189	240	6	improve	improve	VERB
admet-189	240	7	neural	neural	ADJ
admet-189	240	8	prosthetic	prosthetic	ADJ
admet-189	240	9	devices	device	NOUN
admet-189	240	10	for	for	ADP
admet-189	240	11	deep	deep	ADJ
admet-189	240	12	brain	brain	NOUN
admet-189	240	13	stimulation	stimulation	NOUN
admet-189	240	14	with	with	ADP
admet-189	240	15	better	well	ADJ
admet-189	240	16	contact	contact	NOUN
admet-189	240	17	with	with	ADP
admet-189	240	18	the	the	DET
admet-189	240	19	brain	brain	NOUN
admet-189	240	20	.	.	PUNCT
admet-189	241	1	4	4	X
admet-189	241	2	.	.	X
admet-189	241	3	nanotechnology	nanotechnology	NOUN
admet-189	241	4	can	can	AUX
admet-189	241	5	also	also	ADV
admet-189	241	6	help	help	VERB
admet-189	241	7	improve	improve	VERB
admet-189	241	8	precision	precision	NOUN
admet-189	241	9	in	in	ADP
admet-189	241	10	neurosurgery	neurosurgery	NOUN
admet-189	241	11	through	through	ADP
admet-189	241	12	nano	nano	NOUN
admet-189	241	13	-	-	PUNCT
admet-189	241	14	level	level	NOUN
admet-189	241	15	precision	precision	NOUN
admet-189	241	16	of	of	ADP
admet-189	241	17	laser	laser	NOUN
admet-189	241	18	axotomies	axotomie	NOUN
admet-189	241	19	.	.	PUNCT
admet-189	242	1	5	5	X
admet-189	242	2	.	.	X
admet-189	242	3	lastly	lastly	ADV
admet-189	242	4	,	,	PUNCT
admet-189	242	5	nanotechnology	nanotechnology	NOUN
admet-189	242	6	may	may	AUX
admet-189	242	7	be	be	AUX
admet-189	242	8	employed	employ	VERB
admet-189	242	9	to	to	PART
admet-189	242	10	develop	develop	VERB
admet-189	242	11	platforms	platform	NOUN
admet-189	242	12	for	for	ADP
admet-189	242	13	effective	effective	ADJ
admet-189	242	14	stem	stem	NOUN
admet-189	242	15	cell	cell	NOUN
admet-189	242	16	therapy	therapy	NOUN
admet-189	242	17	through	through	ADP
admet-189	242	18	various	various	ADJ
admet-189	242	19	tissue	tissue	NOUN
admet-189	242	20	engineering	engineering	NOUN
admet-189	242	21	approaches	approach	NOUN
admet-189	242	22	.	.	PUNCT
admet-189	243	1	the	the	DET
admet-189	243	2	role	role	NOUN
admet-189	243	3	of	of	ADP
admet-189	243	4	nanotechnology	nanotechnology	NOUN
admet-189	243	5	in	in	ADP
admet-189	243	6	the	the	DET
admet-189	243	7	development	development	NOUN
admet-189	243	8	of	of	ADP
admet-189	243	9	smart	smart	ADJ
admet-189	243	10	platforms	platform	NOUN
admet-189	243	11	for	for	ADP
admet-189	243	12	the	the	DET
admet-189	243	13	diagnosis	diagnosis	NOUN
admet-189	243	14	and	and	CCONJ
admet-189	243	15	treatment	treatment	NOUN
admet-189	243	16	in	in	ADP
admet-189	243	17	pd	pd	PROPN
admet-189	243	18	are	be	AUX
admet-189	243	19	discussed	discuss	VERB
admet-189	243	20	in	in	ADP
admet-189	243	21	the	the	DET
admet-189	243	22	subsequent	subsequent	ADJ
admet-189	243	23	parts	part	NOUN
admet-189	243	24	of	of	ADP
admet-189	243	25	the	the	DET
admet-189	243	26	review	review	NOUN
admet-189	243	27	.	.	PUNCT
admet-189	244	1	nanotechnology	nanotechnology	NOUN
admet-189	244	2	-	-	PUNCT
admet-189	244	3	based	base	VERB
admet-189	244	4	platforms	platform	NOUN
admet-189	244	5	for	for	ADP
admet-189	244	6	diagnosis	diagnosis	NOUN
admet-189	244	7	a	a	DET
admet-189	244	8	brief	brief	ADJ
admet-189	244	9	outline	outline	NOUN
admet-189	244	10	of	of	ADP
admet-189	244	11	the	the	DET
admet-189	244	12	technologies	technology	NOUN
admet-189	244	13	developed	develop	VERB
admet-189	244	14	for	for	ADP
admet-189	244	15	the	the	DET
admet-189	244	16	diagnosis	diagnosis	NOUN
admet-189	244	17	of	of	ADP
admet-189	244	18	pd	pd	PROPN
admet-189	244	19	is	be	AUX
admet-189	244	20	shown	show	VERB
admet-189	244	21	in	in	ADP
admet-189	244	22	figure	figure	NOUN
admet-189	244	23	2	2	NUM
admet-189	244	24	.	.	PUNCT
admet-189	244	25	nanotechnology	nanotechnology	NOUN
admet-189	244	26	is	be	AUX
admet-189	244	27	thus	thus	ADV
admet-189	244	28	being	be	AUX
admet-189	244	29	infused	infuse	VERB
admet-189	244	30	into	into	ADP
admet-189	244	31	the	the	DET
admet-189	244	32	in	in	ADV
admet-189	244	33	vitro	vitro	X
admet-189	244	34	diagnostics	diagnostic	NOUN
admet-189	244	35	,	,	PUNCT
admet-189	244	36	novel	novel	NOUN
admet-189	244	37	biomarker	biomarker	NOUN
admet-189	244	38	identification	identification	NOUN
admet-189	244	39	and	and	CCONJ
admet-189	244	40	bioimaging	bioimaging	NOUN
admet-189	244	41	modalities	modality	NOUN
admet-189	244	42	for	for	ADP
admet-189	244	43	the	the	DET
admet-189	244	44	diagnosis	diagnosis	NOUN
admet-189	244	45	of	of	ADP
admet-189	244	46	pd	pd	PROPN
admet-189	244	47	.	.	PROPN
admet-189	244	48	r.	r.	PROPN
admet-189	244	49	banerjee	banerjee	PROPN
admet-189	244	50	et	et	PROPN
admet-189	244	51	al	al	PROPN
admet-189	244	52	.	.	PROPN
admet-189	244	53	admet	admet	PROPN
admet-189	244	54	&	&	CCONJ
admet-189	244	55	dmpk	dmpk	PROPN
admet-189	244	56	3(3	3(3	NUM
admet-189	244	57	)	)	PUNCT
admet-189	244	58	(	(	PUNCT
admet-189	244	59	2015	2015	NUM
admet-189	244	60	)	)	PUNCT
admet-189	244	61	155	155	NUM
admet-189	244	62	-	-	SYM
admet-189	244	63	181	181	NUM
admet-189	244	64	162	162	NUM
admet-189	244	65	figure	figure	NOUN
admet-189	244	66	2	2	NUM
admet-189	244	67	.	.	PUNCT
admet-189	244	68	use	use	NOUN
admet-189	244	69	of	of	ADP
admet-189	244	70	nanotechnology	nanotechnology	NOUN
admet-189	244	71	in	in	ADP
admet-189	244	72	diagnosis	diagnosis	NOUN
admet-189	244	73	of	of	ADP
admet-189	244	74	parkinson	parkinson	NOUN
admet-189	244	75	’s	’s	PART
admet-189	244	76	disease	disease	NOUN
admet-189	244	77	parkinson	parkinson	NOUN
admet-189	244	78	’s	’s	PART
admet-189	244	79	disease	disease	NOUN
admet-189	244	80	faces	face	VERB
admet-189	244	81	the	the	DET
admet-189	244	82	yet	yet	ADV
admet-189	244	83	unmet	unmet	NOUN
admet-189	244	84	need	need	NOUN
admet-189	244	85	for	for	ADP
admet-189	244	86	development	development	NOUN
admet-189	244	87	of	of	ADP
admet-189	244	88	well	well	ADV
admet-189	244	89	-	-	PUNCT
admet-189	244	90	established	establish	VERB
admet-189	244	91	and	and	CCONJ
admet-189	244	92	validated	validated	ADJ
admet-189	244	93	biomarkers	biomarker	NOUN
admet-189	244	94	[	[	X
admet-189	244	95	58	58	NUM
admet-189	244	96	]	]	PUNCT
admet-189	244	97	.	.	PUNCT
admet-189	245	1	hence	hence	ADV
admet-189	245	2	,	,	PUNCT
admet-189	245	3	most	most	ADJ
admet-189	245	4	of	of	ADP
admet-189	245	5	the	the	DET
admet-189	245	6	present	present	ADJ
admet-189	245	7	day	day	NOUN
admet-189	245	8	end	end	NOUN
admet-189	245	9	-	-	PUNCT
admet-189	245	10	points	point	NOUN
admet-189	245	11	in	in	ADP
admet-189	245	12	the	the	DET
admet-189	245	13	assessment	assessment	NOUN
admet-189	245	14	of	of	ADP
admet-189	245	15	patient	patient	ADJ
admet-189	245	16	response	response	NOUN
admet-189	245	17	in	in	ADP
admet-189	245	18	the	the	DET
admet-189	245	19	clinics	clinic	NOUN
admet-189	245	20	as	as	ADV
admet-189	245	21	well	well	ADV
admet-189	245	22	as	as	ADP
admet-189	245	23	in	in	ADP
admet-189	245	24	large	large	ADJ
admet-189	245	25	clinical	clinical	ADJ
admet-189	245	26	trials	trial	NOUN
admet-189	245	27	depend	depend	VERB
admet-189	245	28	on	on	ADP
admet-189	245	29	subjective	subjective	ADJ
admet-189	245	30	measures	measure	NOUN
admet-189	245	31	of	of	ADP
admet-189	245	32	patient	patient	ADJ
admet-189	245	33	response	response	NOUN
admet-189	245	34	and	and	CCONJ
admet-189	245	35	scores	score	NOUN
admet-189	245	36	obtained	obtain	VERB
admet-189	245	37	using	use	VERB
admet-189	245	38	scales	scale	NOUN
admet-189	245	39	like	like	ADP
admet-189	245	40	the	the	DET
admet-189	245	41	unified	unified	ADJ
admet-189	245	42	parkinson	parkinson	NOUN
admet-189	245	43	's	's	PART
admet-189	245	44	disease	disease	NOUN
admet-189	245	45	rating	rating	NOUN
admet-189	245	46	scale	scale	NOUN
admet-189	245	47	[	[	X
admet-189	245	48	58	58	NUM
admet-189	245	49	]	]	PUNCT
admet-189	245	50	.	.	PUNCT
admet-189	246	1	as	as	ADP
admet-189	246	2	an	an	DET
admet-189	246	3	improvement	improvement	NOUN
admet-189	246	4	of	of	ADP
admet-189	246	5	the	the	DET
admet-189	246	6	classical	classical	ADJ
admet-189	246	7	clinical	clinical	ADJ
admet-189	246	8	features	feature	NOUN
admet-189	246	9	,	,	PUNCT
admet-189	246	10	these	these	DET
admet-189	246	11	scales	scale	NOUN
admet-189	246	12	that	that	PRON
admet-189	246	13	included	include	VERB
admet-189	246	14	features	feature	NOUN
admet-189	246	15	like	like	ADP
admet-189	246	16	response	response	NOUN
admet-189	246	17	to	to	ADP
admet-189	246	18	levodopa	levodopa	NOUN
admet-189	246	19	treatment	treatment	NOUN
admet-189	246	20	along	along	ADP
admet-189	246	21	with	with	ADP
admet-189	246	22	motor	motor	NOUN
admet-189	246	23	evaluation	evaluation	NOUN
admet-189	246	24	were	be	AUX
admet-189	246	25	developed	develop	VERB
admet-189	246	26	to	to	PART
admet-189	246	27	improve	improve	VERB
admet-189	246	28	accuracy	accuracy	NOUN
admet-189	246	29	of	of	ADP
admet-189	246	30	a	a	DET
admet-189	246	31	clinical	clinical	ADJ
admet-189	246	32	diagnosis	diagnosis	NOUN
admet-189	247	1	[	[	X
admet-189	247	2	7	7	NUM
admet-189	247	3	]	]	PUNCT
admet-189	247	4	.	.	PUNCT
admet-189	248	1	however	however	ADV
admet-189	248	2	these	these	DET
admet-189	248	3	scales	scale	NOUN
admet-189	248	4	still	still	ADV
admet-189	248	5	needed	need	VERB
admet-189	248	6	an	an	DET
admet-189	248	7	expert	expert	NOUN
admet-189	248	8	clinician	clinician	NOUN
admet-189	248	9	.	.	PUNCT
admet-189	249	1	in	in	ADP
admet-189	249	2	pd	pd	PROPN
admet-189	249	3	specifically	specifically	ADV
admet-189	249	4	,	,	PUNCT
admet-189	249	5	the	the	DET
admet-189	249	6	clinical	clinical	ADJ
admet-189	249	7	characters	character	NOUN
admet-189	249	8	can	can	AUX
admet-189	249	9	be	be	AUX
admet-189	249	10	substantially	substantially	ADV
admet-189	249	11	masked	mask	VERB
admet-189	249	12	due	due	ADP
admet-189	249	13	to	to	ADP
admet-189	249	14	compensatory	compensatory	ADJ
admet-189	249	15	mechanisms	mechanism	NOUN
admet-189	249	16	for	for	ADP
admet-189	249	17	many	many	ADJ
admet-189	249	18	years	year	NOUN
admet-189	249	19	and	and	CCONJ
admet-189	249	20	it	it	PRON
admet-189	249	21	is	be	AUX
admet-189	249	22	during	during	ADP
admet-189	249	23	this	this	DET
admet-189	249	24	long	long	ADJ
admet-189	249	25	prodromal	prodromal	ADJ
admet-189	249	26	period	period	NOUN
admet-189	249	27	that	that	PRON
admet-189	249	28	there	there	PRON
admet-189	249	29	is	be	VERB
admet-189	249	30	further	further	ADJ
admet-189	249	31	progression	progression	NOUN
admet-189	249	32	of	of	ADP
admet-189	249	33	parkinson	parkinson	NOUN
admet-189	249	34	’s	’s	PART
admet-189	249	35	disease	disease	NOUN
admet-189	249	36	.	.	PUNCT
admet-189	250	1	[	[	X
admet-189	250	2	7	7	NUM
admet-189	250	3	]	]	PUNCT
admet-189	250	4	.	.	PUNCT
admet-189	251	1	hence	hence	ADV
admet-189	251	2	,	,	PUNCT
admet-189	251	3	a	a	DET
admet-189	251	4	framework	framework	NOUN
admet-189	251	5	needs	need	VERB
admet-189	251	6	to	to	PART
admet-189	251	7	be	be	AUX
admet-189	251	8	developed	develop	VERB
admet-189	251	9	for	for	ADP
admet-189	251	10	incorporating	incorporate	VERB
admet-189	251	11	clinical	clinical	ADJ
admet-189	251	12	knowledge	knowledge	NOUN
admet-189	251	13	,	,	PUNCT
admet-189	251	14	pathology	pathology	NOUN
admet-189	251	15	,	,	PUNCT
admet-189	251	16	genetics	genetic	NOUN
admet-189	251	17	and	and	CCONJ
admet-189	251	18	molecular	molecular	ADJ
admet-189	251	19	mechanisms	mechanism	NOUN
admet-189	251	20	along	along	ADV
admet-189	251	21	with	with	ADP
admet-189	251	22	objective	objective	ADJ
admet-189	251	23	tests	test	NOUN
admet-189	251	24	for	for	ADP
admet-189	251	25	defining	define	VERB
admet-189	251	26	the	the	DET
admet-189	251	27	criteria	criterion	NOUN
admet-189	251	28	for	for	ADP
admet-189	251	29	the	the	DET
admet-189	251	30	diagnosis	diagnosis	NOUN
admet-189	251	31	of	of	ADP
admet-189	251	32	parkinson	parkinson	NOUN
admet-189	251	33	’s	’s	PART
admet-189	251	34	disease	disease	NOUN
admet-189	251	35	[	[	X
admet-189	251	36	7	7	NUM
admet-189	251	37	]	]	PUNCT
admet-189	251	38	.	.	PUNCT
admet-189	252	1	this	this	PRON
admet-189	252	2	has	have	AUX
admet-189	252	3	led	lead	VERB
admet-189	252	4	to	to	PART
admet-189	252	5	effort	effort	VERB
admet-189	252	6	like	like	ADP
admet-189	252	7	the	the	DET
admet-189	252	8	parkinson	parkinson	NOUN
admet-189	252	9	’s	’s	PART
admet-189	252	10	progression	progression	NOUN
admet-189	252	11	markers	marker	NOUN
admet-189	252	12	initiative	initiative	NOUN
admet-189	252	13	(	(	PUNCT
admet-189	252	14	ppmi	ppmi	NOUN
admet-189	252	15	)	)	PUNCT
admet-189	252	16	funded	fund	VERB
admet-189	252	17	by	by	ADP
admet-189	252	18	the	the	DET
admet-189	252	19	michael	michael	PROPN
admet-189	252	20	j.	j.	PROPN
admet-189	252	21	fox	fox	PROPN
admet-189	252	22	foundation	foundation	PROPN
admet-189	252	23	as	as	ADP
admet-189	252	24	an	an	DET
admet-189	252	25	effort	effort	NOUN
admet-189	252	26	to	to	PART
admet-189	252	27	meet	meet	VERB
admet-189	252	28	the	the	DET
admet-189	252	29	unmet	unmet	NOUN
admet-189	252	30	need	need	NOUN
admet-189	252	31	of	of	ADP
admet-189	252	32	finding	find	VERB
admet-189	252	33	suitable	suitable	ADJ
admet-189	252	34	biomarkers	biomarker	NOUN
admet-189	252	35	.	.	PUNCT
admet-189	253	1	various	various	ADJ
admet-189	253	2	platforms	platform	NOUN
admet-189	253	3	to	to	PART
admet-189	253	4	detect	detect	VERB
admet-189	253	5	and	and	CCONJ
admet-189	253	6	quantify	quantify	VERB
admet-189	253	7	these	these	DET
admet-189	253	8	biomarkers	biomarker	NOUN
admet-189	253	9	,	,	PUNCT
admet-189	253	10	pd	pd	ADJ
admet-189	253	11	-	-	PUNCT
admet-189	253	12	associated	associate	VERB
admet-189	253	13	pathologies	pathology	NOUN
admet-189	253	14	,	,	PUNCT
admet-189	253	15	imaging	imaging	NOUN
admet-189	253	16	modalities	modality	NOUN
admet-189	253	17	and	and	CCONJ
admet-189	253	18	clinical	clinical	ADJ
admet-189	253	19	abnormalities	abnormality	NOUN
admet-189	253	20	are	be	AUX
admet-189	253	21	being	be	AUX
admet-189	253	22	considered	consider	VERB
admet-189	253	23	in	in	ADP
admet-189	253	24	the	the	DET
admet-189	253	25	diagnosis	diagnosis	NOUN
admet-189	253	26	of	of	ADP
admet-189	253	27	parkinson	parkinson	NOUN
admet-189	253	28	’s	’s	PART
admet-189	253	29	disease	disease	NOUN
admet-189	253	30	.	.	PUNCT
admet-189	254	1	a	a	DET
admet-189	254	2	variety	variety	NOUN
admet-189	254	3	of	of	ADP
admet-189	254	4	nanoparticles	nanoparticle	NOUN
admet-189	254	5	manufactured	manufacture	VERB
admet-189	254	6	from	from	ADP
admet-189	254	7	zinc	zinc	NOUN
admet-189	254	8	oxide	oxide	NOUN
admet-189	254	9	,	,	PUNCT
admet-189	254	10	carbon	carbon	NOUN
admet-189	254	11	nanotubes	nanotube	NOUN
admet-189	254	12	,	,	PUNCT
admet-189	254	13	fullerenes	fullerene	NOUN
admet-189	254	14	etc	etc	X
admet-189	254	15	.	.	X
admet-189	254	16	are	be	AUX
admet-189	254	17	described	describe	VERB
admet-189	254	18	here	here	ADV
admet-189	254	19	which	which	PRON
admet-189	254	20	have	have	VERB
admet-189	254	21	the	the	DET
admet-189	254	22	potential	potential	NOUN
admet-189	254	23	to	to	PART
admet-189	254	24	be	be	AUX
admet-189	254	25	used	use	VERB
admet-189	254	26	in	in	ADP
admet-189	254	27	the	the	DET
admet-189	254	28	diagnosis	diagnosis	NOUN
admet-189	254	29	of	of	ADP
admet-189	254	30	pd	pd	PROPN
admet-189	254	31	.	.	PROPN
admet-189	254	32	detection	detection	NOUN
admet-189	254	33	of	of	ADP
admet-189	254	34	biomarkers	biomarker	NOUN
admet-189	254	35	the	the	DET
admet-189	254	36	ppmi	ppmi	NOUN
admet-189	254	37	study	study	NOUN
admet-189	254	38	is	be	AUX
admet-189	254	39	performing	perform	VERB
admet-189	254	40	clinical	clinical	ADJ
admet-189	254	41	tests	test	NOUN
admet-189	254	42	on	on	ADP
admet-189	254	43	blood	blood	NOUN
admet-189	254	44	,	,	PUNCT
admet-189	254	45	urine	urine	NOUN
admet-189	254	46	and	and	CCONJ
admet-189	254	47	csf	csf	ADJ
admet-189	254	48	samples	sample	NOUN
admet-189	254	49	;	;	PUNCT
admet-189	254	50	performing	perform	VERB
admet-189	254	51	neuroimaging	neuroimage	VERB
admet-189	254	52	to	to	PART
admet-189	254	53	identify	identify	VERB
admet-189	254	54	better	well	ADJ
admet-189	254	55	markers	marker	NOUN
admet-189	254	56	of	of	ADP
admet-189	254	57	the	the	DET
admet-189	254	58	earlier	early	ADJ
admet-189	254	59	and	and	CCONJ
admet-189	254	60	accurate	accurate	ADJ
admet-189	254	61	diagnosis	diagnosis	NOUN
admet-189	254	62	of	of	ADP
admet-189	254	63	pd	pd	PROPN
admet-189	254	64	and	and	CCONJ
admet-189	254	65	its	its	PRON
admet-189	254	66	progression	progression	NOUN
admet-189	254	67	[	[	X
admet-189	254	68	59	59	NUM
admet-189	254	69	]	]	PUNCT
admet-189	254	70	.	.	PUNCT
admet-189	255	1	the	the	DET
admet-189	255	2	quantification	quantification	NOUN
admet-189	255	3	of	of	ADP
admet-189	255	4	dopamine	dopamine	NOUN
admet-189	255	5	has	have	AUX
admet-189	255	6	been	be	AUX
admet-189	255	7	extensively	extensively	ADV
admet-189	255	8	used	use	VERB
admet-189	255	9	and	and	CCONJ
admet-189	255	10	has	have	AUX
admet-189	255	11	traditionally	traditionally	ADV
admet-189	255	12	been	be	AUX
admet-189	255	13	estimated	estimate	VERB
admet-189	255	14	using	use	VERB
admet-189	255	15	spectrophotometry	spectrophotometry	NOUN
admet-189	255	16	and	and	CCONJ
admet-189	255	17	chromatography	chromatography	NOUN
admet-189	255	18	.	.	PUNCT
admet-189	256	1	nanotechnology	nanotechnology	NOUN
admet-189	256	2	platforms	platform	NOUN
admet-189	256	3	for	for	ADP
admet-189	256	4	detection	detection	NOUN
admet-189	256	5	of	of	ADP
admet-189	256	6	dopamine	dopamine	NOUN
admet-189	256	7	:	:	PUNCT
admet-189	256	8	there	there	PRON
admet-189	256	9	are	be	VERB
admet-189	256	10	a	a	DET
admet-189	256	11	number	number	NOUN
admet-189	256	12	of	of	ADP
admet-189	256	13	nanotechnology	nanotechnology	NOUN
admet-189	256	14	-	-	PUNCT
admet-189	256	15	based	base	VERB
admet-189	256	16	approaches	approach	NOUN
admet-189	256	17	that	that	PRON
admet-189	256	18	simultaneously	simultaneously	ADV
admet-189	256	19	detect	detect	VERB
admet-189	256	20	dopamine	dopamine	NOUN
admet-189	256	21	with	with	ADP
admet-189	256	22	other	other	ADJ
admet-189	256	23	biomarkers	biomarker	NOUN
admet-189	256	24	.	.	PUNCT
admet-189	257	1	tashkhourian	tashkhourian	PROPN
admet-189	257	2	et	et	PROPN
admet-189	257	3	al	al	PROPN
admet-189	257	4	.	.	PROPN
admet-189	257	5	developed	develop	VERB
admet-189	257	6	a	a	DET
admet-189	257	7	modified	modify	VERB
admet-189	257	8	carbon	carbon	NOUN
admet-189	257	9	-	-	PUNCT
admet-189	257	10	paste	paste	NOUN
admet-189	257	11	electrode	electrode	NOUN
admet-189	257	12	for	for	ADP
admet-189	257	13	simultaneous	simultaneous	ADJ
admet-189	257	14	quantification	quantification	NOUN
admet-189	257	15	of	of	ADP
admet-189	257	16	dopamine	dopamine	NOUN
admet-189	257	17	and	and	CCONJ
admet-189	257	18	ascorbic	ascorbic	NOUN
admet-189	257	19	acid	acid	NOUN
admet-189	257	20	[	[	X
admet-189	257	21	60	60	NUM
admet-189	257	22	]	]	PUNCT
admet-189	257	23	.	.	PUNCT
admet-189	258	1	the	the	DET
admet-189	258	2	electrodes	electrode	NOUN
admet-189	258	3	were	be	AUX
admet-189	258	4	modified	modify	VERB
admet-189	258	5	to	to	PART
admet-189	258	6	incorporate	incorporate	VERB
admet-189	258	7	silver	silver	ADJ
admet-189	258	8	nanoparticles	nanoparticle	NOUN
admet-189	258	9	and	and	CCONJ
admet-189	258	10	carbon	carbon	NOUN
admet-189	258	11	nanotubes	nanotube	NOUN
admet-189	258	12	,	,	PUNCT
admet-189	258	13	which	which	PRON
admet-189	258	14	led	lead	VERB
admet-189	258	15	to	to	ADP
admet-189	258	16	more	more	ADV
admet-189	258	17	admet	admet	PROPN
admet-189	258	18	&	&	CCONJ
admet-189	258	19	dmpk	dmpk	PROPN
admet-189	258	20	3(3	3(3	NUM
admet-189	258	21	)	)	PUNCT
admet-189	258	22	(	(	PUNCT
admet-189	258	23	2015	2015	NUM
admet-189	258	24	)	)	PUNCT
admet-189	258	25	155	155	NUM
admet-189	258	26	-	-	SYM
admet-189	258	27	181	181	NUM
admet-189	258	28	nanotechnology	nanotechnology	NOUN
admet-189	258	29	platforms	platform	NOUN
admet-189	258	30	in	in	ADP
admet-189	258	31	parkinson	parkinson	NOUN
admet-189	258	32	’s	’s	PART
admet-189	258	33	disease	disease	NOUN
admet-189	258	34	doi	doi	NOUN
admet-189	258	35	:	:	PUNCT
admet-189	258	36	10.5599	10.5599	NUM
admet-189	258	37	/	/	SYM
admet-189	258	38	admet.3.3.189	admet.3.3.189	ADP
admet-189	258	39	163	163	NUM
admet-189	258	40	efficient	efficient	ADJ
admet-189	258	41	electrochemical	electrochemical	ADJ
admet-189	258	42	catalysis	catalysis	NOUN
admet-189	258	43	with	with	ADP
admet-189	258	44	high	high	ADJ
admet-189	258	45	selectivity	selectivity	NOUN
admet-189	258	46	and	and	CCONJ
admet-189	258	47	sensitivity	sensitivity	NOUN
admet-189	258	48	and	and	CCONJ
admet-189	258	49	a	a	DET
admet-189	258	50	detection	detection	NOUN
admet-189	258	51	limit	limit	NOUN
admet-189	258	52	in	in	ADP
admet-189	258	53	micromolars	micromolar	NOUN
admet-189	258	54	for	for	ADP
admet-189	258	55	both	both	CCONJ
admet-189	258	56	the	the	DET
admet-189	258	57	compounds	compound	NOUN
admet-189	258	58	[	[	X
admet-189	258	59	60	60	NUM
admet-189	258	60	]	]	PUNCT
admet-189	258	61	.	.	PUNCT
admet-189	259	1	in	in	ADP
admet-189	259	2	another	another	DET
admet-189	259	3	study	study	NOUN
admet-189	259	4	by	by	ADP
admet-189	259	5	yue	yue	PROPN
admet-189	259	6	and	and	CCONJ
admet-189	259	7	colleagues	colleague	NOUN
admet-189	259	8	,	,	PUNCT
admet-189	259	9	zinc	zinc	NOUN
admet-189	259	10	oxide	oxide	NOUN
admet-189	259	11	(	(	PUNCT
admet-189	259	12	zno	zno	NOUN
admet-189	259	13	)	)	PUNCT
admet-189	259	14	nanowire	nanowire	NOUN
admet-189	259	15	arrays	array	NOUN
admet-189	259	16	(	(	PUNCT
admet-189	259	17	each	each	DET
admet-189	259	18	nanowire	nanowire	NOUN
admet-189	259	19	being	be	AUX
admet-189	259	20	sub-100	sub-100	NOUN
admet-189	259	21	nm	nm	VERB
admet-189	259	22	in	in	ADP
admet-189	259	23	diameter	diameter	NOUN
admet-189	259	24	and	and	CCONJ
admet-189	259	25	a	a	DET
admet-189	259	26	couple	couple	NOUN
admet-189	259	27	of	of	ADP
admet-189	259	28	microns	micron	NOUN
admet-189	259	29	in	in	ADP
admet-189	259	30	height	height	NOUN
admet-189	259	31	)	)	PUNCT
admet-189	259	32	were	be	AUX
admet-189	259	33	prepared	prepare	VERB
admet-189	259	34	upon	upon	SCONJ
admet-189	259	35	a	a	DET
admet-189	259	36	three	three	NUM
admet-189	259	37	dimensional	dimensional	ADJ
admet-189	259	38	foam	foam	NOUN
admet-189	259	39	made	make	VERB
admet-189	259	40	of	of	ADP
admet-189	259	41	graphene	graphene	NOUN
admet-189	259	42	and	and	CCONJ
admet-189	259	43	the	the	DET
admet-189	259	44	assembly	assembly	NOUN
admet-189	259	45	could	could	AUX
admet-189	259	46	selectively	selectively	ADV
admet-189	259	47	detect	detect	VERB
admet-189	259	48	dopamine	dopamine	NOUN
admet-189	259	49	along	along	ADP
admet-189	259	50	with	with	ADP
admet-189	259	51	urate	urate	NOUN
admet-189	259	52	and	and	CCONJ
admet-189	259	53	ascorbate	ascorbate	NOUN
admet-189	259	54	by	by	ADP
admet-189	259	55	a	a	DET
admet-189	259	56	method	method	NOUN
admet-189	259	57	called	call	VERB
admet-189	259	58	differential	differential	ADJ
admet-189	259	59	pulse	pulse	NOUN
admet-189	259	60	voltammetry	voltammetry	NOUN
admet-189	259	61	.	.	PUNCT
admet-189	260	1	the	the	DET
admet-189	260	2	addition	addition	NOUN
admet-189	260	3	of	of	ADP
admet-189	260	4	nanowires	nanowire	NOUN
admet-189	260	5	lead	lead	VERB
admet-189	260	6	to	to	ADP
admet-189	260	7	high	high	ADJ
admet-189	260	8	electrical	electrical	ADJ
admet-189	260	9	conductivity	conductivity	NOUN
admet-189	260	10	and	and	CCONJ
admet-189	260	11	enhancement	enhancement	NOUN
admet-189	260	12	of	of	ADP
admet-189	260	13	sensitivity	sensitivity	NOUN
admet-189	260	14	of	of	ADP
admet-189	260	15	electrochemical	electrochemical	ADJ
admet-189	260	16	biosensors	biosensor	NOUN
admet-189	260	17	leading	lead	VERB
admet-189	260	18	to	to	ADP
admet-189	260	19	reduction	reduction	NOUN
admet-189	260	20	in	in	ADP
admet-189	260	21	the	the	DET
admet-189	260	22	detection	detection	NOUN
admet-189	260	23	limit	limit	NOUN
admet-189	260	24	to	to	ADP
admet-189	260	25	1	1	NUM
admet-189	260	26	nanomolar	nanomolar	ADJ
admet-189	260	27	for	for	ADP
admet-189	260	28	dopamine	dopamine	NOUN
admet-189	260	29	and	and	CCONJ
admet-189	260	30	uric	uric	ADJ
admet-189	260	31	acid	acid	NOUN
admet-189	260	32	in	in	ADP
admet-189	260	33	the	the	DET
admet-189	260	34	serum	serum	NOUN
admet-189	260	35	of	of	ADP
admet-189	260	36	pd	pd	PROPN
admet-189	260	37	patients	patient	NOUN
admet-189	260	38	[	[	X
admet-189	260	39	61	61	NUM
admet-189	260	40	]	]	PUNCT
admet-189	260	41	.	.	PUNCT
admet-189	261	1	the	the	DET
admet-189	261	2	field	field	NOUN
admet-189	261	3	testing	testing	NOUN
admet-189	261	4	of	of	ADP
admet-189	261	5	this	this	DET
admet-189	261	6	array	array	NOUN
admet-189	261	7	lead	lead	VERB
admet-189	261	8	to	to	ADP
admet-189	261	9	the	the	DET
admet-189	261	10	interesting	interesting	ADJ
admet-189	261	11	finding	finding	NOUN
admet-189	261	12	of	of	ADP
admet-189	261	13	a	a	DET
admet-189	261	14	reduced	reduce	VERB
admet-189	261	15	ua	ua	NOUN
admet-189	261	16	level	level	NOUN
admet-189	261	17	in	in	ADP
admet-189	261	18	7	7	NUM
admet-189	261	19	pd	pd	NOUN
admet-189	261	20	patients	patient	NOUN
admet-189	261	21	than	than	ADP
admet-189	261	22	in	in	ADP
admet-189	261	23	healthy	healthy	ADJ
admet-189	261	24	individuals	individual	NOUN
admet-189	261	25	which	which	PRON
admet-189	261	26	can	can	AUX
admet-189	261	27	make	make	VERB
admet-189	261	28	uric	uric	ADJ
admet-189	261	29	acid	acid	NOUN
admet-189	261	30	a	a	DET
admet-189	261	31	potential	potential	ADJ
admet-189	261	32	biomarker	biomarker	NOUN
admet-189	261	33	in	in	ADP
admet-189	261	34	the	the	DET
admet-189	261	35	diagnosis	diagnosis	NOUN
admet-189	261	36	of	of	ADP
admet-189	261	37	pd	pd	NOUN
admet-189	261	38	[	[	X
admet-189	261	39	61	61	NUM
admet-189	261	40	]	]	PUNCT
admet-189	261	41	.	.	PUNCT
admet-189	262	1	in	in	ADP
admet-189	262	2	yet	yet	ADV
admet-189	262	3	another	another	DET
admet-189	262	4	modification	modification	NOUN
admet-189	262	5	,	,	PUNCT
admet-189	262	6	kurzatkowska	kurzatkowska	NOUN
admet-189	262	7	et	et	PROPN
admet-189	262	8	al	al	PROPN
admet-189	262	9	.	.	PROPN
admet-189	262	10	developed	develop	VERB
admet-189	262	11	ion	ion	NOUN
admet-189	262	12	-	-	PUNCT
admet-189	262	13	channel	channel	NOUN
admet-189	262	14	mimetic	mimetic	ADJ
admet-189	262	15	self	self	NOUN
admet-189	262	16	-	-	PUNCT
admet-189	262	17	assembled	assemble	VERB
admet-189	262	18	monolayers	monolayer	NOUN
admet-189	262	19	of	of	ADP
admet-189	262	20	macrocyclic	macrocyclic	NOUN
admet-189	262	21	polyamines	polyamine	NOUN
admet-189	262	22	deposited	deposit	VERB
admet-189	262	23	onto	onto	ADP
admet-189	262	24	gold	gold	NOUN
admet-189	262	25	electrodes	electrode	NOUN
admet-189	262	26	for	for	ADP
admet-189	262	27	electrochemical	electrochemical	ADJ
admet-189	262	28	determination	determination	NOUN
admet-189	262	29	of	of	ADP
admet-189	262	30	dopamine	dopamine	NOUN
admet-189	262	31	[	[	X
admet-189	262	32	62	62	NUM
admet-189	262	33	]	]	PUNCT
admet-189	262	34	.	.	PUNCT
admet-189	263	1	the	the	DET
admet-189	263	2	corrole	corrole	ADJ
admet-189	263	3	molecules	molecule	NOUN
admet-189	263	4	covalently	covalently	ADV
admet-189	263	5	attached	attach	VERB
admet-189	263	6	on	on	ADP
admet-189	263	7	the	the	DET
admet-189	263	8	surface	surface	NOUN
admet-189	263	9	of	of	ADP
admet-189	263	10	gold	gold	NOUN
admet-189	263	11	electrodes	electrode	NOUN
admet-189	263	12	was	be	AUX
admet-189	263	13	an	an	DET
admet-189	263	14	example	example	NOUN
admet-189	263	15	of	of	ADP
admet-189	263	16	biomimicry	biomimicry	NOUN
admet-189	263	17	of	of	ADP
admet-189	263	18	ligand	ligand	NOUN
admet-189	263	19	-	-	PUNCT
admet-189	263	20	gated	gate	VERB
admet-189	263	21	ion	ion	NOUN
admet-189	263	22	channels	channel	NOUN
admet-189	263	23	making	make	VERB
admet-189	263	24	the	the	DET
admet-189	263	25	electrode	electrode	NOUN
admet-189	263	26	surface	surface	NOUN
admet-189	263	27	semi	semi	ADJ
admet-189	263	28	-	-	ADJ
admet-189	263	29	permeable	permeable	ADJ
admet-189	263	30	to	to	ADP
admet-189	263	31	a	a	DET
admet-189	263	32	redox	redox	ADJ
admet-189	263	33	marker	marker	NOUN
admet-189	263	34	.	.	PUNCT
admet-189	264	1	upon	upon	SCONJ
admet-189	264	2	addition	addition	NOUN
admet-189	264	3	of	of	ADP
admet-189	264	4	dopamine	dopamine	NOUN
admet-189	264	5	,	,	PUNCT
admet-189	264	6	a	a	DET
admet-189	264	7	corrole	corrole	ADJ
admet-189	264	8	-	-	PUNCT
admet-189	264	9	dopamine	dopamine	NOUN
admet-189	264	10	complex	complex	NOUN
admet-189	264	11	is	be	AUX
admet-189	264	12	formed	form	VERB
admet-189	264	13	on	on	ADP
admet-189	264	14	the	the	DET
admet-189	264	15	monolayer	monolayer	NOUN
admet-189	264	16	leading	lead	VERB
admet-189	264	17	to	to	ADP
admet-189	264	18	the	the	DET
admet-189	264	19	recording	recording	NOUN
admet-189	264	20	of	of	ADP
admet-189	264	21	a	a	DET
admet-189	264	22	positive	positive	ADJ
admet-189	264	23	charge	charge	NOUN
admet-189	264	24	on	on	ADP
admet-189	264	25	the	the	DET
admet-189	264	26	electrode	electrode	NOUN
admet-189	264	27	[	[	X
admet-189	264	28	62	62	NUM
admet-189	264	29	]	]	PUNCT
admet-189	264	30	.	.	PUNCT
admet-189	265	1	this	this	PRON
admet-189	265	2	allowed	allow	VERB
admet-189	265	3	the	the	DET
admet-189	265	4	detection	detection	NOUN
admet-189	265	5	limits	limit	VERB
admet-189	265	6	to	to	PART
admet-189	265	7	go	go	VERB
admet-189	265	8	down	down	ADP
admet-189	265	9	to	to	ADP
admet-189	265	10	the	the	DET
admet-189	265	11	picomolar	picomolar	ADJ
admet-189	265	12	range	range	NOUN
admet-189	265	13	[	[	X
admet-189	265	14	62	62	NUM
admet-189	265	15	]	]	PUNCT
admet-189	265	16	.	.	PUNCT
admet-189	266	1	thus	thus	ADV
admet-189	266	2	,	,	PUNCT
admet-189	266	3	the	the	DET
admet-189	266	4	detection	detection	NOUN
admet-189	266	5	of	of	ADP
admet-189	266	6	dopamine	dopamine	NOUN
admet-189	266	7	can	can	AUX
admet-189	266	8	be	be	AUX
admet-189	266	9	made	make	VERB
admet-189	266	10	more	more	ADV
admet-189	266	11	sensitive	sensitive	ADJ
admet-189	266	12	and	and	CCONJ
admet-189	266	13	the	the	DET
admet-189	266	14	detection	detection	NOUN
admet-189	266	15	limits	limit	NOUN
admet-189	266	16	can	can	AUX
admet-189	266	17	be	be	AUX
admet-189	266	18	reduced	reduce	VERB
admet-189	266	19	by	by	ADP
admet-189	266	20	orders	order	NOUN
admet-189	266	21	of	of	ADP
admet-189	266	22	magnitude	magnitude	NOUN
admet-189	266	23	with	with	ADP
admet-189	266	24	the	the	DET
admet-189	266	25	incorporation	incorporation	NOUN
admet-189	266	26	of	of	ADP
admet-189	266	27	nanotechnology	nanotechnology	NOUN
admet-189	266	28	-	-	PUNCT
admet-189	266	29	based	base	VERB
admet-189	266	30	smart	smart	ADJ
admet-189	266	31	platforms	platform	NOUN
admet-189	266	32	.	.	PUNCT
admet-189	267	1	mitochondrial	mitochondrial	ADJ
admet-189	267	2	dysfunction	dysfunction	NOUN
admet-189	267	3	:	:	PUNCT
admet-189	267	4	as	as	ADP
admet-189	267	5	another	another	DET
admet-189	267	6	example	example	NOUN
admet-189	267	7	,	,	PUNCT
admet-189	267	8	pd	pd	PROPN
admet-189	267	9	has	have	AUX
admet-189	267	10	been	be	AUX
admet-189	267	11	associated	associate	VERB
admet-189	267	12	with	with	ADP
admet-189	267	13	mitochondrial	mitochondrial	ADJ
admet-189	267	14	dysfunction	dysfunction	NOUN
admet-189	267	15	and	and	CCONJ
admet-189	267	16	the	the	DET
admet-189	267	17	inhibition	inhibition	NOUN
admet-189	267	18	of	of	ADP
admet-189	267	19	complex	complex	ADJ
admet-189	267	20	i	i	PRON
admet-189	267	21	comprising	comprising	NOUN
admet-189	267	22	of	of	ADP
admet-189	267	23	nadh	nadh	NOUN
admet-189	267	24	:	:	PUNCT
admet-189	267	25	ubiquinone	ubiquinone	PROPN
admet-189	267	26	oxidoreductase	oxidoreductase	NOUN
admet-189	267	27	has	have	AUX
admet-189	267	28	been	be	AUX
admet-189	267	29	implicated	implicate	VERB
admet-189	267	30	in	in	ADP
admet-189	267	31	the	the	DET
admet-189	267	32	demise	demise	NOUN
admet-189	267	33	of	of	ADP
admet-189	267	34	dopaminergic	dopaminergic	ADJ
admet-189	267	35	neurons	neuron	NOUN
admet-189	267	36	[	[	X
admet-189	267	37	19	19	NUM
admet-189	267	38	]	]	PUNCT
admet-189	267	39	.	.	PUNCT
admet-189	268	1	ma	ma	PROPN
admet-189	268	2	et	et	PROPN
admet-189	268	3	al	al	PROPN
admet-189	268	4	.	.	PROPN
admet-189	268	5	developed	develop	VERB
admet-189	268	6	ubiquinone	ubiquinone	PROPN
admet-189	268	7	-	-	PUNCT
admet-189	268	8	quantum	quantum	ADJ
admet-189	268	9	dot	dot	NOUN
admet-189	268	10	(	(	PUNCT
admet-189	268	11	cdse	cdse	NOUN
admet-189	268	12	/	/	SYM
admet-189	268	13	zns	zns	NOUN
admet-189	268	14	)	)	PUNCT
admet-189	268	15	bioconjugates	bioconjugate	NOUN
admet-189	268	16	in	in	ADP
admet-189	268	17	which	which	PRON
admet-189	268	18	complex	complex	NOUN
admet-189	268	19	i	i	PRON
admet-189	268	20	and	and	CCONJ
admet-189	268	21	nadh	nadh	NOUN
admet-189	268	22	could	could	AUX
admet-189	268	23	modulate	modulate	VERB
admet-189	268	24	the	the	DET
admet-189	268	25	emission	emission	NOUN
admet-189	268	26	from	from	ADP
admet-189	268	27	the	the	DET
admet-189	268	28	nanocomplexes	nanocomplexe	NOUN
admet-189	268	29	by	by	ADP
admet-189	268	30	simulating	simulate	VERB
admet-189	268	31	the	the	DET
admet-189	268	32	electron	electron	NOUN
admet-189	268	33	-	-	PUNCT
admet-189	268	34	transfer	transfer	NOUN
admet-189	268	35	system	system	NOUN
admet-189	268	36	part	part	NOUN
admet-189	268	37	of	of	ADP
admet-189	268	38	the	the	DET
admet-189	268	39	mitochondrial	mitochondrial	ADJ
admet-189	268	40	respiratory	respiratory	ADJ
admet-189	268	41	chain	chain	NOUN
admet-189	268	42	[	[	X
admet-189	268	43	63	63	NUM
admet-189	268	44	]	]	PUNCT
admet-189	268	45	.	.	PUNCT
admet-189	269	1	the	the	DET
admet-189	269	2	authors	author	NOUN
admet-189	269	3	showed	show	VERB
admet-189	269	4	that	that	SCONJ
admet-189	269	5	the	the	DET
admet-189	269	6	bioconjugates	bioconjugate	NOUN
admet-189	269	7	could	could	AUX
admet-189	269	8	be	be	AUX
admet-189	269	9	used	use	VERB
admet-189	269	10	to	to	PART
admet-189	269	11	monitor	monitor	VERB
admet-189	269	12	changes	change	NOUN
admet-189	269	13	in	in	ADP
admet-189	269	14	fluorescence	fluorescence	NOUN
admet-189	269	15	to	to	PART
admet-189	269	16	trace	trace	NOUN
admet-189	269	17	complex	complex	ADJ
admet-189	269	18	i	i	PROPN
admet-189	269	19	levels	level	NOUN
admet-189	269	20	in	in	ADP
admet-189	269	21	human	human	ADJ
admet-189	269	22	neuroblastoma	neuroblastoma	NOUN
admet-189	269	23	sh	sh	PROPN
admet-189	269	24	-	-	PUNCT
admet-189	269	25	sy5y	sy5y	PROPN
admet-189	269	26	cells	cell	NOUN
admet-189	269	27	[	[	X
admet-189	269	28	63	63	NUM
admet-189	269	29	]	]	PUNCT
admet-189	269	30	.	.	PUNCT
admet-189	270	1	though	though	SCONJ
admet-189	270	2	in	in	ADP
admet-189	270	3	the	the	DET
admet-189	270	4	proof	proof	NOUN
admet-189	270	5	of	of	ADP
admet-189	270	6	concept	concept	NOUN
admet-189	270	7	stage	stage	NOUN
admet-189	270	8	,	,	PUNCT
admet-189	270	9	this	this	DET
admet-189	270	10	technique	technique	NOUN
admet-189	270	11	has	have	VERB
admet-189	270	12	the	the	DET
admet-189	270	13	potential	potential	NOUN
admet-189	270	14	to	to	PART
admet-189	270	15	serve	serve	VERB
admet-189	270	16	as	as	ADP
admet-189	270	17	an	an	DET
admet-189	270	18	in	in	ADP
admet-189	270	19	vitro	vitro	X
admet-189	270	20	biosensor	biosensor	NOUN
admet-189	270	21	for	for	ADP
admet-189	270	22	the	the	DET
admet-189	270	23	early	early	ADJ
admet-189	270	24	detection	detection	NOUN
admet-189	270	25	of	of	ADP
admet-189	270	26	pd	pd	PROPN
admet-189	270	27	and	and	CCONJ
admet-189	270	28	in	in	ADP
admet-189	270	29	monitoring	monitor	VERB
admet-189	270	30	disease	disease	NOUN
admet-189	270	31	progression	progression	NOUN
admet-189	270	32	.	.	PUNCT
admet-189	271	1	α	α	X
admet-189	271	2	-	-	PUNCT
admet-189	271	3	synuclein	synuclein	NOUN
admet-189	271	4	detection	detection	NOUN
admet-189	271	5	:	:	PUNCT
admet-189	271	6	as	as	SCONJ
admet-189	271	7	described	describe	VERB
admet-189	271	8	earlier	early	ADV
admet-189	271	9	,	,	PUNCT
admet-189	271	10	α	α	X
admet-189	271	11	-	-	PUNCT
admet-189	271	12	synuclein	synuclein	NOUN
admet-189	271	13	is	be	AUX
admet-189	271	14	a	a	DET
admet-189	271	15	very	very	ADV
admet-189	271	16	important	important	ADJ
admet-189	271	17	neuronal	neuronal	ADJ
admet-189	271	18	protein	protein	NOUN
admet-189	271	19	associated	associate	VERB
admet-189	271	20	with	with	ADP
admet-189	271	21	pd	pd	PROPN
admet-189	271	22	and	and	CCONJ
admet-189	271	23	present	present	ADJ
admet-189	271	24	day	day	NOUN
admet-189	271	25	strategies	strategy	NOUN
admet-189	271	26	for	for	ADP
admet-189	271	27	its	its	PRON
admet-189	271	28	quantitative	quantitative	ADJ
admet-189	271	29	detection	detection	NOUN
admet-189	271	30	include	include	VERB
admet-189	271	31	sophisticated	sophisticated	ADJ
admet-189	271	32	,	,	PUNCT
admet-189	271	33	time	time	NOUN
admet-189	271	34	-	-	PUNCT
admet-189	271	35	consuming	consume	VERB
admet-189	271	36	instruments	instrument	NOUN
admet-189	271	37	including	include	VERB
admet-189	271	38	nmr	nmr	NOUN
admet-189	271	39	spectroscopy	spectroscopy	NOUN
admet-189	271	40	,	,	PUNCT
admet-189	271	41	fluorescence	fluorescence	NOUN
admet-189	271	42	measurements	measurement	NOUN
admet-189	271	43	,	,	PUNCT
admet-189	271	44	western	western	ADJ
admet-189	271	45	blotting	blotting	NOUN
admet-189	271	46	and	and	CCONJ
admet-189	271	47	size	size	NOUN
admet-189	271	48	-	-	PUNCT
admet-189	271	49	exclusion	exclusion	NOUN
admet-189	271	50	chromatography	chromatography	NOUN
admet-189	271	51	[	[	X
admet-189	271	52	64	64	NUM
admet-189	271	53	]	]	PUNCT
admet-189	271	54	.	.	PUNCT
admet-189	272	1	an	an	PRON
admet-189	272	2	et	et	PROPN
admet-189	272	3	al	al	PROPN
admet-189	272	4	.	.	PROPN
admet-189	272	5	developed	develop	VERB
admet-189	272	6	highly	highly	ADV
admet-189	272	7	ordered	order	VERB
admet-189	272	8	microfabricated	microfabricate	VERB
admet-189	272	9	arrays	array	NOUN
admet-189	272	10	using	use	VERB
admet-189	272	11	gold	gold	NOUN
admet-189	272	12	-	-	PUNCT
admet-189	272	13	doped	dope	VERB
admet-189	272	14	tio2	tio2	NOUN
admet-189	272	15	nanotubes	nanotube	NOUN
admet-189	272	16	for	for	ADP
admet-189	272	17	photoelectrochemical	photoelectrochemical	ADJ
admet-189	272	18	detection	detection	NOUN
admet-189	272	19	of	of	ADP
admet-189	272	20	α	α	NOUN
admet-189	272	21	-	-	PUNCT
admet-189	272	22	synuclein	synuclein	NOUN
admet-189	272	23	[	[	X
admet-189	272	24	64	64	NUM
admet-189	272	25	]	]	PUNCT
admet-189	272	26	.	.	PUNCT
admet-189	273	1	the	the	DET
admet-189	273	2	arrays	array	NOUN
admet-189	273	3	were	be	AUX
admet-189	273	4	effective	effective	ADJ
admet-189	273	5	platforms	platform	NOUN
admet-189	273	6	for	for	ADP
admet-189	273	7	the	the	DET
admet-189	273	8	immobilization	immobilization	NOUN
admet-189	273	9	of	of	ADP
admet-189	273	10	primary	primary	ADJ
admet-189	273	11	antibodies	antibody	NOUN
admet-189	273	12	while	while	SCONJ
admet-189	273	13	retaining	retain	VERB
admet-189	273	14	their	their	PRON
admet-189	273	15	stability	stability	NOUN
admet-189	273	16	and	and	CCONJ
admet-189	273	17	α	α	NOUN
admet-189	273	18	-	-	PUNCT
admet-189	273	19	synuclein	synuclein	NOUN
admet-189	273	20	binding	bind	VERB
admet-189	273	21	[	[	X
admet-189	273	22	64	64	NUM
admet-189	273	23	]	]	PUNCT
admet-189	273	24	.	.	PUNCT
admet-189	274	1	then	then	ADV
admet-189	274	2	,	,	PUNCT
admet-189	274	3	the	the	DET
admet-189	274	4	attachment	attachment	NOUN
admet-189	274	5	of	of	ADP
admet-189	274	6	secondary	secondary	ADJ
admet-189	274	7	antibody	antibody	NOUN
admet-189	274	8	and	and	CCONJ
admet-189	274	9	gold	gold	NOUN
admet-189	274	10	nanoparticle	nanoparticle	NOUN
admet-189	274	11	-	-	PUNCT
admet-189	274	12	conjugated	conjugate	VERB
admet-189	274	13	glucose	glucose	NOUN
admet-189	274	14	oxidase	oxidase	NOUN
admet-189	274	15	,	,	PUNCT
admet-189	274	16	allowed	allow	VERB
admet-189	274	17	excellent	excellent	ADJ
admet-189	274	18	sensitivity	sensitivity	NOUN
admet-189	274	19	by	by	ADP
admet-189	274	20	signal	signal	ADJ
admet-189	274	21	amplification	amplification	NOUN
admet-189	274	22	.	.	PUNCT
admet-189	275	1	glucose	glucose	NOUN
admet-189	275	2	oxidase	oxidase	NOUN
admet-189	275	3	catalyzed	catalyze	VERB
admet-189	275	4	the	the	DET
admet-189	275	5	conversion	conversion	NOUN
admet-189	275	6	of	of	ADP
admet-189	275	7	glucose	glucose	NOUN
admet-189	275	8	into	into	ADP
admet-189	275	9	gluconic	gluconic	ADJ
admet-189	275	10	acid	acid	NOUN
admet-189	275	11	and	and	CCONJ
admet-189	275	12	hydrogen	hydrogen	NOUN
admet-189	275	13	peroxide	peroxide	NOUN
admet-189	275	14	.	.	PUNCT
admet-189	276	1	upon	upon	SCONJ
admet-189	276	2	irradiating	irradiate	VERB
admet-189	276	3	the	the	DET
admet-189	276	4	other	other	ADJ
admet-189	276	5	side	side	NOUN
admet-189	276	6	of	of	ADP
admet-189	276	7	the	the	DET
admet-189	276	8	titanium	titanium	NOUN
admet-189	276	9	foil	foil	NOUN
admet-189	276	10	,	,	PUNCT
admet-189	276	11	the	the	DET
admet-189	276	12	holes	hole	NOUN
admet-189	276	13	that	that	PRON
admet-189	276	14	were	be	AUX
admet-189	276	15	formed	form	VERB
admet-189	276	16	within	within	ADP
admet-189	276	17	the	the	DET
admet-189	276	18	valence	valence	NOUN
admet-189	276	19	band	band	NOUN
admet-189	276	20	of	of	ADP
admet-189	276	21	the	the	DET
admet-189	276	22	nanotubes	nanotube	NOUN
admet-189	276	23	could	could	AUX
admet-189	276	24	be	be	AUX
admet-189	276	25	scavenged	scavenge	VERB
admet-189	276	26	by	by	ADP
admet-189	276	27	the	the	DET
admet-189	276	28	peroxide	peroxide	NOUN
admet-189	276	29	leading	lead	VERB
admet-189	276	30	to	to	ADP
admet-189	276	31	a	a	DET
admet-189	276	32	photocurrent	photocurrent	ADJ
admet-189	276	33	proportional	proportional	NOUN
admet-189	276	34	to	to	ADP
admet-189	276	35	concentrations	concentration	NOUN
admet-189	276	36	of	of	ADP
admet-189	276	37	α	α	NOUN
admet-189	276	38	-	-	PUNCT
admet-189	276	39	synuclein	synuclein	NOUN
admet-189	276	40	with	with	ADP
admet-189	276	41	a	a	DET
admet-189	276	42	detection	detection	NOUN
admet-189	276	43	concentration	concentration	NOUN
admet-189	276	44	in	in	ADP
admet-189	276	45	the	the	DET
admet-189	276	46	range	range	NOUN
admet-189	276	47	of	of	ADP
admet-189	276	48	pg	pg	PROPN
admet-189	276	49	/	/	SYM
admet-189	276	50	ml	ml	PROPN
admet-189	276	51	[	[	X
admet-189	276	52	64	64	NUM
admet-189	276	53	]	]	PUNCT
admet-189	276	54	.	.	PUNCT
admet-189	277	1	other	other	ADJ
admet-189	277	2	novel	novel	ADJ
admet-189	277	3	concepts	concept	NOUN
admet-189	277	4	:	:	PUNCT
admet-189	277	5	there	there	PRON
admet-189	277	6	are	be	VERB
admet-189	277	7	a	a	DET
admet-189	277	8	few	few	ADJ
admet-189	277	9	other	other	ADJ
admet-189	277	10	novel	novel	ADJ
admet-189	277	11	diagnostic	diagnostic	ADJ
admet-189	277	12	concepts	concept	NOUN
admet-189	277	13	that	that	PRON
admet-189	277	14	are	be	AUX
admet-189	277	15	emerging	emerge	VERB
admet-189	277	16	.	.	PUNCT
admet-189	278	1	the	the	DET
admet-189	278	2	use	use	NOUN
admet-189	278	3	of	of	ADP
admet-189	278	4	breath	breath	NOUN
admet-189	278	5	tests	test	NOUN
admet-189	278	6	to	to	PART
admet-189	278	7	diagnose	diagnose	VERB
admet-189	278	8	neurodegenerative	neurodegenerative	ADJ
admet-189	278	9	disorders	disorder	NOUN
admet-189	278	10	is	be	AUX
admet-189	278	11	one	one	NUM
admet-189	278	12	such	such	ADJ
admet-189	278	13	advancement	advancement	NOUN
admet-189	278	14	.	.	PUNCT
admet-189	279	1	a	a	DET
admet-189	279	2	number	number	NOUN
admet-189	279	3	of	of	ADP
admet-189	279	4	volatile	volatile	ADJ
admet-189	279	5	organic	organic	ADJ
admet-189	279	6	compounds	compound	NOUN
admet-189	279	7	like	like	ADP
admet-189	279	8	styrene	styrene	NOUN
admet-189	279	9	,	,	PUNCT
admet-189	279	10	butylated	butylate	VERB
admet-189	279	11	hydroxytoluene	hydroxytoluene	NOUN
admet-189	279	12	and	and	CCONJ
admet-189	279	13	hexadecane	hexadecane	NOUN
admet-189	279	14	have	have	AUX
admet-189	279	15	been	be	AUX
admet-189	279	16	found	find	VERB
admet-189	279	17	in	in	ADP
admet-189	279	18	the	the	DET
admet-189	279	19	breath	breath	NOUN
admet-189	279	20	of	of	ADP
admet-189	279	21	pd	pd	NOUN
admet-189	279	22	patients	patient	NOUN
admet-189	280	1	[	[	X
admet-189	280	2	65	65	NUM
admet-189	280	3	]	]	PUNCT
admet-189	280	4	.	.	PUNCT
admet-189	281	1	as	as	ADP
admet-189	281	2	an	an	DET
admet-189	281	3	example	example	NOUN
admet-189	281	4	of	of	ADP
admet-189	281	5	the	the	DET
admet-189	281	6	use	use	NOUN
admet-189	281	7	of	of	ADP
admet-189	281	8	nanotechnology	nanotechnology	NOUN
admet-189	281	9	in	in	ADP
admet-189	281	10	the	the	DET
admet-189	281	11	sensing	sensing	NOUN
admet-189	281	12	of	of	ADP
admet-189	281	13	such	such	ADJ
admet-189	281	14	novel	novel	ADJ
admet-189	281	15	compounds	compound	NOUN
admet-189	281	16	,	,	PUNCT
admet-189	281	17	r.	r.	PROPN
admet-189	281	18	banerjee	banerjee	PROPN
admet-189	281	19	et	et	PROPN
admet-189	281	20	al	al	PROPN
admet-189	281	21	.	.	PROPN
admet-189	281	22	admet	admet	PROPN
admet-189	281	23	&	&	CCONJ
admet-189	281	24	dmpk	dmpk	PROPN
admet-189	281	25	3(3	3(3	NUM
admet-189	281	26	)	)	PUNCT
admet-189	281	27	(	(	PUNCT
admet-189	281	28	2015	2015	NUM
admet-189	281	29	)	)	PUNCT
admet-189	281	30	155	155	NUM
admet-189	281	31	-	-	SYM
admet-189	281	32	181	181	NUM
admet-189	281	33	164	164	NUM
admet-189	281	34	organically	organically	ADV
admet-189	281	35	functionalized	functionalize	VERB
admet-189	281	36	nanoparticles	nanoparticle	NOUN
admet-189	281	37	like	like	ADP
admet-189	281	38	carbon	carbon	NOUN
admet-189	281	39	nanotubes	nanotube	NOUN
admet-189	281	40	and	and	CCONJ
admet-189	281	41	gold	gold	NOUN
admet-189	281	42	nanoparticles	nanoparticle	NOUN
admet-189	281	43	were	be	AUX
admet-189	281	44	used	use	VERB
admet-189	281	45	by	by	ADP
admet-189	281	46	tisch	tisch	PROPN
admet-189	281	47	and	and	CCONJ
admet-189	281	48	co	co	NOUN
admet-189	281	49	-	-	NOUN
admet-189	281	50	workers	worker	NOUN
admet-189	281	51	[	[	X
admet-189	281	52	66	66	NUM
admet-189	281	53	]	]	PUNCT
admet-189	281	54	.	.	PUNCT
admet-189	282	1	the	the	DET
admet-189	282	2	sensors	sensor	NOUN
admet-189	282	3	were	be	AUX
admet-189	282	4	effective	effective	ADJ
admet-189	282	5	in	in	ADP
admet-189	282	6	distinguishing	distinguish	VERB
admet-189	282	7	the	the	DET
admet-189	282	8	breath	breath	NOUN
admet-189	282	9	prints	print	NOUN
admet-189	282	10	of	of	ADP
admet-189	282	11	pd	pd	PROPN
admet-189	282	12	from	from	ADP
admet-189	282	13	healthy	healthy	ADJ
admet-189	282	14	states	state	NOUN
admet-189	282	15	with	with	ADP
admet-189	282	16	an	an	DET
admet-189	282	17	accuracy	accuracy	NOUN
admet-189	282	18	of	of	ADP
admet-189	282	19	78	78	NUM
admet-189	282	20	%	%	NOUN
admet-189	282	21	[	[	X
admet-189	282	22	66	66	NUM
admet-189	282	23	]	]	PUNCT
admet-189	282	24	.	.	PUNCT
admet-189	283	1	similarly	similarly	ADV
admet-189	283	2	,	,	PUNCT
admet-189	283	3	the	the	DET
admet-189	283	4	technology	technology	NOUN
admet-189	283	5	could	could	AUX
admet-189	283	6	identify	identify	VERB
admet-189	283	7	alzheimer	alzheimer	PROPN
admet-189	283	8	’s	’s	PART
admet-189	283	9	disease	disease	NOUN
admet-189	283	10	and	and	CCONJ
admet-189	283	11	differentiate	differentiate	VERB
admet-189	283	12	it	it	PRON
admet-189	283	13	from	from	ADP
admet-189	283	14	pd	pd	PROPN
admet-189	283	15	.	.	PROPN
admet-189	283	16	improved	improve	VERB
admet-189	283	17	imaging	imaging	NOUN
admet-189	283	18	technologies	technology	NOUN
admet-189	283	19	imaging	imaging	NOUN
admet-189	283	20	in	in	ADP
admet-189	283	21	pd	pd	PROPN
admet-189	283	22	is	be	AUX
admet-189	283	23	dependent	dependent	ADJ
admet-189	283	24	on	on	ADP
admet-189	283	25	a	a	DET
admet-189	283	26	number	number	NOUN
admet-189	283	27	of	of	ADP
admet-189	283	28	sophisticated	sophisticated	ADJ
admet-189	283	29	techniques	technique	NOUN
admet-189	283	30	like	like	ADP
admet-189	283	31	cranial	cranial	ADJ
admet-189	283	32	ct	ct	PROPN
admet-189	283	33	,	,	PUNCT
admet-189	283	34	mri	mri	NOUN
admet-189	283	35	,	,	PUNCT
admet-189	283	36	pet	pet	NOUN
admet-189	283	37	and	and	CCONJ
admet-189	283	38	spect	spect	NOUN
admet-189	283	39	which	which	PRON
admet-189	283	40	are	be	AUX
admet-189	283	41	mostly	mostly	ADV
admet-189	283	42	available	available	ADJ
admet-189	283	43	at	at	ADP
admet-189	283	44	advanced	advanced	ADJ
admet-189	283	45	healthcare	healthcare	NOUN
admet-189	283	46	centres	centre	NOUN
admet-189	283	47	and	and	CCONJ
admet-189	283	48	are	be	AUX
admet-189	283	49	expensive	expensive	ADJ
admet-189	283	50	.	.	PUNCT
admet-189	284	1	a	a	DET
admet-189	284	2	number	number	NOUN
admet-189	284	3	of	of	ADP
admet-189	284	4	experimental	experimental	ADJ
admet-189	284	5	approaches	approach	NOUN
admet-189	284	6	are	be	AUX
admet-189	284	7	being	be	AUX
admet-189	284	8	developed	develop	VERB
admet-189	284	9	and	and	CCONJ
admet-189	284	10	have	have	VERB
admet-189	284	11	potential	potential	NOUN
admet-189	284	12	for	for	ADP
admet-189	284	13	the	the	DET
admet-189	284	14	imaging	imaging	NOUN
admet-189	284	15	and	and	CCONJ
admet-189	284	16	earlier	early	ADJ
admet-189	284	17	diagnosis	diagnosis	NOUN
admet-189	284	18	of	of	ADP
admet-189	284	19	pd	pd	PROPN
admet-189	284	20	.	.	PUNCT
admet-189	285	1	a	a	DET
admet-189	285	2	few	few	ADJ
admet-189	285	3	of	of	ADP
admet-189	285	4	these	these	PRON
admet-189	285	5	have	have	AUX
admet-189	285	6	been	be	AUX
admet-189	285	7	elaborated	elaborate	VERB
admet-189	285	8	below	below	ADV
admet-189	285	9	.	.	PUNCT
admet-189	286	1	iron	iron	NOUN
admet-189	286	2	metabolism	metabolism	NOUN
admet-189	286	3	:	:	PUNCT
admet-189	286	4	homeostasis	homeostasis	NOUN
admet-189	286	5	of	of	ADP
admet-189	286	6	various	various	ADJ
admet-189	286	7	metal	metal	NOUN
admet-189	286	8	ions	ion	NOUN
admet-189	286	9	which	which	PRON
admet-189	286	10	are	be	AUX
admet-189	286	11	found	find	VERB
admet-189	286	12	to	to	PART
admet-189	286	13	be	be	AUX
admet-189	286	14	altered	alter	VERB
admet-189	286	15	characterize	characterize	NOUN
admet-189	286	16	neurodegeneration	neurodegeneration	NOUN
admet-189	286	17	in	in	ADP
admet-189	286	18	pd	pd	PROPN
admet-189	286	19	.	.	PROPN
admet-189	286	20	ortega	ortega	PROPN
admet-189	286	21	and	and	CCONJ
admet-189	286	22	colleagues	colleague	NOUN
admet-189	286	23	used	use	VERB
admet-189	286	24	this	this	PRON
admet-189	286	25	for	for	ADP
admet-189	286	26	chemical	chemical	ADJ
admet-189	286	27	nano	nano	NOUN
admet-189	286	28	-	-	PUNCT
admet-189	286	29	imaging	imaging	NOUN
admet-189	286	30	in	in	ADP
admet-189	286	31	vitro	vitro	X
admet-189	286	32	using	use	VERB
admet-189	286	33	synchrotron	synchrotron	NOUN
admet-189	286	34	x	x	ADJ
admet-189	286	35	-	-	NOUN
admet-189	286	36	ray	ray	NOUN
admet-189	286	37	fluorescence	fluorescence	NOUN
admet-189	286	38	nanoprobe	nanoprobe	NOUN
admet-189	286	39	(	(	PUNCT
admet-189	286	40	88	88	NUM
admet-189	286	41	nm	nm	ADJ
admet-189	286	42	beam	beam	NOUN
admet-189	286	43	)	)	PUNCT
admet-189	286	44	which	which	PRON
admet-189	286	45	allowed	allow	VERB
admet-189	286	46	detection	detection	NOUN
admet-189	286	47	of	of	ADP
admet-189	286	48	10−18	10−18	NUM
admet-189	286	49	g	g	NOUN
admet-189	286	50	of	of	ADP
admet-189	286	51	iron	iron	NOUN
admet-189	286	52	within	within	ADP
admet-189	286	53	cellular	cellular	ADJ
admet-189	286	54	structures	structure	NOUN
admet-189	286	55	around	around	ADP
admet-189	286	56	100	100	NUM
admet-189	286	57	nm	nm	NOUN
admet-189	286	58	diameter	diameter	NOUN
admet-189	287	1	[	[	X
admet-189	287	2	67	67	NUM
admet-189	287	3	]	]	PUNCT
admet-189	287	4	.	.	PUNCT
admet-189	288	1	results	result	NOUN
admet-189	288	2	suggested	suggest	VERB
admet-189	288	3	that	that	SCONJ
admet-189	288	4	pd	pd	PROPN
admet-189	288	5	showed	show	VERB
admet-189	288	6	elevation	elevation	NOUN
admet-189	288	7	of	of	ADP
admet-189	288	8	iron	iron	NOUN
admet-189	288	9	in	in	ADP
admet-189	288	10	the	the	DET
admet-189	288	11	substantia	substantia	NOUN
admet-189	288	12	nigra	nigra	PROPN
admet-189	288	13	pars	par	NOUN
admet-189	288	14	compacta	compacta	NOUN
admet-189	288	15	,	,	PUNCT
admet-189	288	16	with	with	ADP
admet-189	288	17	loss	loss	NOUN
admet-189	288	18	of	of	ADP
admet-189	288	19	tyrosine	tyrosine	NOUN
admet-189	288	20	hydroxylase	hydroxylase	NOUN
admet-189	288	21	activity	activity	NOUN
admet-189	288	22	that	that	PRON
admet-189	288	23	may	may	AUX
admet-189	288	24	lead	lead	VERB
admet-189	288	25	to	to	ADP
admet-189	288	26	reduced	reduce	VERB
admet-189	288	27	iron	iron	NOUN
admet-189	288	28	-	-	PUNCT
admet-189	288	29	dopamine	dopamine	NOUN
admet-189	288	30	binding	bind	VERB
admet-189	288	31	making	make	VERB
admet-189	288	32	the	the	DET
admet-189	288	33	dopaminergic	dopaminergic	ADJ
admet-189	288	34	neurons	neuron	NOUN
admet-189	288	35	more	more	ADV
admet-189	288	36	prone	prone	ADJ
admet-189	288	37	to	to	ADP
admet-189	288	38	iron	iron	NOUN
admet-189	288	39	toxicity	toxicity	NOUN
admet-189	288	40	[	[	X
admet-189	288	41	67	67	NUM
admet-189	288	42	]	]	PUNCT
admet-189	288	43	.	.	PUNCT
admet-189	289	1	thus	thus	ADV
admet-189	289	2	,	,	PUNCT
admet-189	289	3	nanoimaging	nanoimaging	NOUN
admet-189	289	4	forms	form	NOUN
admet-189	289	5	an	an	DET
admet-189	289	6	important	important	ADJ
admet-189	289	7	part	part	NOUN
admet-189	289	8	in	in	ADP
admet-189	289	9	the	the	DET
admet-189	289	10	detection	detection	NOUN
admet-189	289	11	of	of	ADP
admet-189	289	12	newer	new	ADJ
admet-189	289	13	pathways	pathway	NOUN
admet-189	289	14	for	for	ADP
admet-189	289	15	neurodegeneration	neurodegeneration	NOUN
admet-189	289	16	in	in	ADP
admet-189	289	17	pd	pd	PROPN
admet-189	289	18	.	.	PROPN
admet-189	289	19	theranostics	theranostic	NOUN
admet-189	289	20	:	:	PUNCT
admet-189	289	21	gdnf	gdnf	PROPN
admet-189	289	22	can	can	AUX
admet-189	289	23	be	be	AUX
admet-189	289	24	delivered	deliver	VERB
admet-189	289	25	as	as	ADP
admet-189	289	26	a	a	DET
admet-189	289	27	neuroprotective	neuroprotective	ADJ
admet-189	289	28	agent	agent	NOUN
admet-189	289	29	using	use	VERB
admet-189	289	30	microbubbles	microbubble	NOUN
admet-189	289	31	which	which	PRON
admet-189	289	32	are	be	AUX
admet-189	289	33	ultrasound	ultrasound	ADV
admet-189	289	34	responsive	responsive	ADJ
admet-189	289	35	[	[	X
admet-189	289	36	68	68	NUM
admet-189	289	37	]	]	PUNCT
admet-189	289	38	.	.	PUNCT
admet-189	290	1	the	the	DET
admet-189	290	2	use	use	NOUN
admet-189	290	3	of	of	ADP
admet-189	290	4	such	such	ADJ
admet-189	290	5	particles	particle	NOUN
admet-189	290	6	in	in	ADP
admet-189	290	7	simultaneous	simultaneous	ADJ
admet-189	290	8	imaging	imaging	NOUN
admet-189	290	9	and	and	CCONJ
admet-189	290	10	therapy	therapy	NOUN
admet-189	290	11	can	can	AUX
admet-189	290	12	give	give	VERB
admet-189	290	13	rise	rise	NOUN
admet-189	290	14	to	to	ADP
admet-189	290	15	a	a	DET
admet-189	290	16	theranostic	theranostic	ADJ
admet-189	290	17	approach	approach	NOUN
admet-189	290	18	in	in	ADP
admet-189	290	19	the	the	DET
admet-189	290	20	management	management	NOUN
admet-189	290	21	of	of	ADP
admet-189	290	22	parkinson	parkinson	NOUN
admet-189	290	23	’s	’s	PART
admet-189	290	24	disease	disease	NOUN
admet-189	290	25	.	.	PUNCT
admet-189	291	1	similar	similar	ADJ
admet-189	291	2	therapies	therapy	NOUN
admet-189	291	3	have	have	AUX
admet-189	291	4	been	be	AUX
admet-189	291	5	developed	develop	VERB
admet-189	291	6	for	for	ADP
admet-189	291	7	the	the	DET
admet-189	291	8	treatment	treatment	NOUN
admet-189	291	9	of	of	ADP
admet-189	291	10	cancers	cancer	NOUN
admet-189	291	11	[	[	X
admet-189	291	12	69	69	NUM
admet-189	291	13	]	]	PUNCT
admet-189	291	14	and	and	CCONJ
admet-189	291	15	is	be	AUX
admet-189	291	16	very	very	ADV
admet-189	291	17	promising	promising	ADJ
admet-189	291	18	.	.	PUNCT
admet-189	292	1	a	a	DET
admet-189	292	2	similar	similar	ADJ
admet-189	292	3	approach	approach	NOUN
admet-189	292	4	is	be	AUX
admet-189	292	5	the	the	DET
admet-189	292	6	development	development	NOUN
admet-189	292	7	of	of	ADP
admet-189	292	8	magnetic	magnetic	ADJ
admet-189	292	9	-	-	PUNCT
admet-189	292	10	field	field	NOUN
admet-189	292	11	responsive	responsive	ADJ
admet-189	292	12	nanoparticles	nanoparticle	NOUN
admet-189	292	13	that	that	PRON
admet-189	292	14	are	be	AUX
admet-189	292	15	capable	capable	ADJ
admet-189	292	16	of	of	ADP
admet-189	292	17	crossing	cross	VERB
admet-189	292	18	anatomical	anatomical	ADJ
admet-189	292	19	barriers	barrier	NOUN
admet-189	292	20	like	like	ADP
admet-189	292	21	the	the	DET
admet-189	292	22	bbb	bbb	NOUN
admet-189	292	23	and	and	CCONJ
admet-189	292	24	respond	respond	VERB
admet-189	292	25	to	to	ADP
admet-189	292	26	an	an	DET
admet-189	292	27	external	external	ADJ
admet-189	292	28	magnetic	magnetic	ADJ
admet-189	292	29	field	field	NOUN
admet-189	292	30	by	by	ADP
admet-189	292	31	releasing	release	VERB
admet-189	292	32	the	the	DET
admet-189	292	33	encapsulated	encapsulate	VERB
admet-189	292	34	therapeutic	therapeutic	ADJ
admet-189	292	35	payloads	payload	NOUN
admet-189	292	36	[	[	X
admet-189	292	37	70	70	NUM
admet-189	292	38	]	]	PUNCT
admet-189	292	39	.	.	PUNCT
admet-189	293	1	the	the	DET
admet-189	293	2	field	field	NOUN
admet-189	293	3	of	of	ADP
admet-189	293	4	theranostics	theranostic	NOUN
admet-189	293	5	is	be	AUX
admet-189	293	6	promising	promise	VERB
admet-189	293	7	and	and	CCONJ
admet-189	293	8	yet	yet	ADV
admet-189	293	9	to	to	PART
admet-189	293	10	be	be	AUX
admet-189	293	11	well	well	ADV
admet-189	293	12	explored	explore	VERB
admet-189	293	13	in	in	ADP
admet-189	293	14	the	the	DET
admet-189	293	15	treatment	treatment	NOUN
admet-189	293	16	of	of	ADP
admet-189	293	17	parkinson	parkinson	NOUN
admet-189	293	18	’s	’s	PART
admet-189	293	19	disease	disease	NOUN
admet-189	293	20	.	.	PUNCT
admet-189	294	1	detection	detection	NOUN
admet-189	294	2	of	of	ADP
admet-189	294	3	cell	cell	NOUN
admet-189	294	4	loss	loss	NOUN
admet-189	294	5	:	:	PUNCT
admet-189	294	6	in	in	ADP
admet-189	294	7	1999	1999	NUM
admet-189	294	8	,	,	PUNCT
admet-189	294	9	damier	damier	NOUN
admet-189	294	10	et	et	PROPN
admet-189	294	11	al	al	PROPN
admet-189	294	12	.	.	PROPN
admet-189	294	13	described	describe	VERB
admet-189	294	14	a	a	DET
admet-189	294	15	protocol	protocol	NOUN
admet-189	294	16	based	base	VERB
admet-189	294	17	on	on	ADP
admet-189	294	18	immunostaining	immunostaine	VERB
admet-189	294	19	a	a	DET
admet-189	294	20	protein	protein	NOUN
admet-189	294	21	existing	exist	VERB
admet-189	294	22	in	in	ADP
admet-189	294	23	afferent	afferent	ADJ
admet-189	294	24	striatonigral	striatonigral	ADJ
admet-189	294	25	fibers	fiber	NOUN
admet-189	294	26	called	call	VERB
admet-189	294	27	calbindin	calbindin	VERB
admet-189	294	28	d28k	d28k	PUNCT
admet-189	295	1	[	[	X
admet-189	295	2	71	71	NUM
admet-189	295	3	]	]	PUNCT
admet-189	295	4	.	.	PUNCT
admet-189	296	1	using	use	VERB
admet-189	296	2	this	this	DET
admet-189	296	3	technique	technique	NOUN
admet-189	296	4	in	in	ADP
admet-189	296	5	post	post	ADJ
admet-189	296	6	-	-	ADJ
admet-189	296	7	mortem	mortem	ADJ
admet-189	296	8	specimens	specimen	NOUN
admet-189	296	9	,	,	PUNCT
admet-189	296	10	researchers	researcher	NOUN
admet-189	296	11	could	could	AUX
admet-189	296	12	delineate	delineate	VERB
admet-189	296	13	60	60	NUM
admet-189	296	14	%	%	NOUN
admet-189	296	15	of	of	ADP
admet-189	296	16	all	all	DET
admet-189	296	17	neurons	neuron	NOUN
admet-189	296	18	containing	contain	VERB
admet-189	296	19	dopamine	dopamine	NOUN
admet-189	296	20	present	present	ADJ
admet-189	296	21	in	in	ADP
admet-189	296	22	the	the	DET
admet-189	296	23	substantia	substantia	NOUN
admet-189	296	24	nigra	nigra	PROPN
admet-189	296	25	pars	par	NOUN
admet-189	296	26	compacta	compacta	NOUN
admet-189	296	27	inside	inside	ADP
admet-189	296	28	the	the	DET
admet-189	296	29	zone	zone	NOUN
admet-189	296	30	that	that	PRON
admet-189	296	31	has	have	AUX
admet-189	296	32	high	high	ADJ
admet-189	296	33	calbindin	calbindin	VERB
admet-189	296	34	(	(	PUNCT
admet-189	296	35	nigral	nigral	ADJ
admet-189	296	36	matrix	matrix	NOUN
admet-189	296	37	)	)	PUNCT
admet-189	296	38	,	,	PUNCT
admet-189	296	39	and	and	CCONJ
admet-189	296	40	the	the	DET
admet-189	296	41	remaining	remain	VERB
admet-189	296	42	40	40	NUM
admet-189	296	43	%	%	NOUN
admet-189	296	44	was	be	AUX
admet-189	296	45	found	find	VERB
admet-189	296	46	to	to	PART
admet-189	296	47	exist	exist	VERB
admet-189	296	48	,	,	PUNCT
admet-189	296	49	packed	pack	VERB
admet-189	296	50	together	together	ADV
admet-189	296	51	as	as	ADP
admet-189	296	52	the	the	DET
admet-189	296	53	zones	zone	NOUN
admet-189	296	54	poor	poor	ADJ
admet-189	296	55	in	in	ADP
admet-189	296	56	calbindin	calbindin	VERB
admet-189	296	57	(	(	PUNCT
admet-189	296	58	nigrosomes	nigrosome	NOUN
admet-189	296	59	)	)	PUNCT
admet-189	296	60	in	in	ADP
admet-189	296	61	the	the	DET
admet-189	296	62	form	form	NOUN
admet-189	296	63	of	of	ADP
admet-189	296	64	invaginated	invaginate	VERB
admet-189	296	65	pockets	pocket	NOUN
admet-189	296	66	within	within	ADP
admet-189	296	67	the	the	DET
admet-189	296	68	nigral	nigral	ADJ
admet-189	296	69	matrix	matrix	NOUN
admet-189	297	1	[	[	X
admet-189	297	2	71	71	NUM
admet-189	297	3	]	]	PUNCT
admet-189	297	4	.	.	PUNCT
admet-189	298	1	the	the	DET
admet-189	298	2	group	group	NOUN
admet-189	298	3	identified	identify	VERB
admet-189	298	4	a	a	DET
admet-189	298	5	mean	mean	ADJ
admet-189	298	6	reduction	reduction	NOUN
admet-189	298	7	of	of	ADP
admet-189	298	8	more	more	ADJ
admet-189	298	9	than	than	ADP
admet-189	298	10	half	half	NOUN
admet-189	298	11	of	of	ADP
admet-189	298	12	the	the	DET
admet-189	298	13	total	total	ADJ
admet-189	298	14	dopamine	dopamine	NOUN
admet-189	298	15	-	-	PUNCT
admet-189	298	16	containing	contain	VERB
admet-189	298	17	neurons	neuron	NOUN
admet-189	298	18	in	in	ADP
admet-189	298	19	pd	pd	PROPN
admet-189	298	20	as	as	SCONJ
admet-189	298	21	compared	compare	VERB
admet-189	298	22	to	to	ADP
admet-189	298	23	controls	control	NOUN
admet-189	298	24	[	[	X
admet-189	298	25	71	71	NUM
admet-189	298	26	]	]	PUNCT
admet-189	298	27	.	.	PUNCT
admet-189	299	1	besides	besides	SCONJ
admet-189	299	2	,	,	PUNCT
admet-189	299	3	the	the	DET
admet-189	299	4	substantia	substantia	NOUN
admet-189	299	5	nigra	nigra	PROPN
admet-189	299	6	pars	par	NOUN
admet-189	299	7	compacta	compacta	NOUN
admet-189	299	8	showed	show	VERB
admet-189	299	9	that	that	SCONJ
admet-189	299	10	the	the	DET
admet-189	299	11	degree	degree	NOUN
admet-189	299	12	of	of	ADP
admet-189	299	13	loss	loss	NOUN
admet-189	299	14	of	of	ADP
admet-189	299	15	dopamine	dopamine	NOUN
admet-189	299	16	-	-	PUNCT
admet-189	299	17	containing	contain	VERB
admet-189	299	18	neurons	neuron	NOUN
admet-189	299	19	correlated	correlate	VERB
admet-189	299	20	with	with	ADP
admet-189	299	21	the	the	DET
admet-189	299	22	duration	duration	NOUN
admet-189	299	23	of	of	ADP
admet-189	299	24	disease	disease	NOUN
admet-189	299	25	[	[	X
admet-189	299	26	71	71	NUM
admet-189	299	27	]	]	PUNCT
admet-189	299	28	.	.	PUNCT
admet-189	300	1	thus	thus	ADV
admet-189	300	2	,	,	PUNCT
admet-189	300	3	the	the	DET
admet-189	300	4	pattern	pattern	NOUN
admet-189	300	5	of	of	ADP
admet-189	300	6	cell	cell	NOUN
admet-189	300	7	loss	loss	NOUN
admet-189	300	8	in	in	ADP
admet-189	300	9	pd	pd	PROPN
admet-189	300	10	was	be	AUX
admet-189	300	11	found	find	VERB
admet-189	300	12	using	use	VERB
admet-189	300	13	this	this	DET
admet-189	300	14	experimental	experimental	ADJ
admet-189	300	15	tool	tool	NOUN
admet-189	300	16	.	.	PUNCT
admet-189	301	1	further	further	ADJ
admet-189	301	2	advancements	advancement	NOUN
admet-189	301	3	in	in	ADP
admet-189	301	4	the	the	DET
admet-189	301	5	imaging	imaging	NOUN
admet-189	301	6	of	of	ADP
admet-189	301	7	cells	cell	NOUN
admet-189	301	8	using	use	VERB
admet-189	301	9	quantum	quantum	ADJ
admet-189	301	10	dots	dot	NOUN
admet-189	301	11	and	and	CCONJ
admet-189	301	12	gold	gold	NOUN
admet-189	301	13	nanoparticles	nanoparticle	NOUN
admet-189	301	14	can	can	AUX
admet-189	301	15	advance	advance	VERB
admet-189	301	16	this	this	DET
admet-189	301	17	imaging	imaging	NOUN
admet-189	301	18	modality	modality	NOUN
admet-189	301	19	to	to	PART
admet-189	301	20	track	track	VERB
admet-189	301	21	pd	pd	NOUN
admet-189	301	22	progression	progression	NOUN
admet-189	301	23	.	.	PUNCT
admet-189	302	1	monitoring	monitor	VERB
admet-189	302	2	clinical	clinical	ADJ
admet-189	302	3	abnormalities	abnormality	NOUN
admet-189	302	4	one	one	NUM
admet-189	302	5	of	of	ADP
admet-189	302	6	the	the	DET
admet-189	302	7	interesting	interesting	ADJ
admet-189	302	8	applications	application	NOUN
admet-189	302	9	in	in	ADP
admet-189	302	10	the	the	DET
admet-189	302	11	diagnosis	diagnosis	NOUN
admet-189	302	12	of	of	ADP
admet-189	302	13	pd	pd	PROPN
admet-189	302	14	is	be	AUX
admet-189	302	15	the	the	DET
admet-189	302	16	detection	detection	NOUN
admet-189	302	17	of	of	ADP
admet-189	302	18	clinical	clinical	ADJ
admet-189	302	19	abnormalities	abnormality	NOUN
admet-189	302	20	.	.	PUNCT
admet-189	303	1	arrays	array	NOUN
admet-189	303	2	of	of	ADP
admet-189	303	3	stretchable	stretchable	ADJ
admet-189	303	4	strain	strain	NOUN
admet-189	303	5	sensors	sensor	NOUN
admet-189	303	6	based	base	VERB
admet-189	303	7	on	on	ADP
admet-189	303	8	silicon	silicon	NOUN
admet-189	303	9	nanomembranes	nanomembrane	NOUN
admet-189	303	10	that	that	PRON
admet-189	303	11	conform	conform	VERB
admet-189	303	12	well	well	ADV
admet-189	303	13	to	to	ADP
admet-189	303	14	the	the	DET
admet-189	303	15	skin	skin	NOUN
admet-189	303	16	have	have	AUX
admet-189	303	17	been	be	AUX
admet-189	303	18	proposed	propose	VERB
admet-189	303	19	as	as	ADP
admet-189	303	20	wearable	wearable	ADJ
admet-189	303	21	devices	device	NOUN
admet-189	303	22	for	for	ADP
admet-189	303	23	detection	detection	NOUN
admet-189	303	24	of	of	ADP
admet-189	303	25	clinical	clinical	ADJ
admet-189	303	26	abnormalities	abnormality	NOUN
admet-189	303	27	[	[	X
admet-189	303	28	72	72	NUM
admet-189	303	29	]	]	PUNCT
admet-189	303	30	.	.	PUNCT
admet-189	304	1	nanofabrication	nanofabrication	PROPN
admet-189	304	2	allows	allow	VERB
admet-189	304	3	the	the	DET
admet-189	304	4	manufacture	manufacture	NOUN
admet-189	304	5	of	of	ADP
admet-189	304	6	such	such	ADJ
admet-189	304	7	sensors	sensor	NOUN
admet-189	304	8	coupled	couple	VERB
admet-189	304	9	with	with	ADP
admet-189	304	10	added	add	VERB
admet-189	304	11	features	feature	NOUN
admet-189	304	12	like	like	ADP
admet-189	304	13	presence	presence	NOUN
admet-189	304	14	of	of	ADP
admet-189	304	15	ultrathin	ultrathin	ADJ
admet-189	304	16	serpentine	serpentine	NOUN
admet-189	304	17	interconnects	interconnect	NOUN
admet-189	304	18	to	to	PART
admet-189	304	19	improve	improve	VERB
admet-189	304	20	the	the	DET
admet-189	304	21	precision	precision	NOUN
admet-189	304	22	of	of	ADP
admet-189	304	23	diagnosis	diagnosis	NOUN
admet-189	304	24	[	[	X
admet-189	304	25	72	72	NUM
admet-189	304	26	]	]	PUNCT
admet-189	304	27	.	.	PUNCT
admet-189	305	1	exposure	exposure	NOUN
admet-189	305	2	to	to	ADP
admet-189	305	3	tension	tension	NOUN
admet-189	305	4	and	and	CCONJ
admet-189	305	5	compression	compression	NOUN
admet-189	305	6	on	on	ADP
admet-189	305	7	a	a	DET
admet-189	305	8	human	human	ADJ
admet-189	305	9	wrist	wrist	NOUN
admet-189	305	10	are	be	AUX
admet-189	305	11	used	use	VERB
admet-189	305	12	for	for	ADP
admet-189	305	13	detection	detection	NOUN
admet-189	305	14	of	of	ADP
admet-189	305	15	frequency	frequency	NOUN
admet-189	305	16	of	of	ADP
admet-189	305	17	tremors	tremor	NOUN
admet-189	305	18	and	and	CCONJ
admet-189	305	19	can	can	AUX
admet-189	305	20	be	be	AUX
admet-189	305	21	of	of	ADP
admet-189	305	22	use	use	NOUN
admet-189	305	23	in	in	ADP
admet-189	305	24	the	the	DET
admet-189	305	25	continuous	continuous	ADJ
admet-189	305	26	monitoring	monitoring	NOUN
admet-189	305	27	of	of	ADP
admet-189	305	28	pd	pd	PROPN
admet-189	305	29	.	.	PROPN
admet-189	305	30	admet	admet	PROPN
admet-189	305	31	&	&	CCONJ
admet-189	305	32	dmpk	dmpk	PROPN
admet-189	305	33	3(3	3(3	NUM
admet-189	305	34	)	)	PUNCT
admet-189	305	35	(	(	PUNCT
admet-189	305	36	2015	2015	NUM
admet-189	305	37	)	)	PUNCT
admet-189	305	38	155	155	NUM
admet-189	305	39	-	-	SYM
admet-189	305	40	181	181	NUM
admet-189	305	41	nanotechnology	nanotechnology	NOUN
admet-189	305	42	platforms	platform	NOUN
admet-189	305	43	in	in	ADP
admet-189	305	44	parkinson	parkinson	NOUN
admet-189	305	45	’s	’s	PART
admet-189	305	46	disease	disease	NOUN
admet-189	305	47	doi	doi	NOUN
admet-189	305	48	:	:	PUNCT
admet-189	305	49	10.5599	10.5599	NUM
admet-189	305	50	/	/	SYM
admet-189	305	51	admet.3.3.189	admet.3.3.189	ADP
admet-189	305	52	165	165	NUM
admet-189	305	53	other	other	ADJ
admet-189	305	54	interesting	interesting	ADJ
admet-189	305	55	clinical	clinical	ADJ
admet-189	305	56	abnormalities	abnormality	NOUN
admet-189	305	57	including	include	VERB
admet-189	305	58	change	change	NOUN
admet-189	305	59	in	in	ADP
admet-189	305	60	handwriting	handwriting	NOUN
admet-189	305	61	have	have	AUX
admet-189	305	62	also	also	ADV
admet-189	305	63	been	be	AUX
admet-189	305	64	explored	explore	VERB
admet-189	305	65	for	for	ADP
admet-189	305	66	the	the	DET
admet-189	305	67	diagnosis	diagnosis	NOUN
admet-189	305	68	of	of	ADP
admet-189	305	69	pd	pd	NOUN
admet-189	306	1	[	[	X
admet-189	306	2	73	73	NUM
admet-189	306	3	]	]	PUNCT
admet-189	306	4	.	.	PUNCT
admet-189	307	1	nanotechnology	nanotechnology	PROPN
admet-189	307	2	platforms	platform	NOUN
admet-189	307	3	for	for	ADP
admet-189	307	4	drug	drug	NOUN
admet-189	307	5	delivery	delivery	NOUN
admet-189	307	6	active	active	ADJ
admet-189	307	7	targeting	target	VERB
admet-189	307	8	by	by	ADP
admet-189	307	9	trojan	trojan	NOUN
admet-189	307	10	horse	horse	NOUN
admet-189	307	11	approach	approach	NOUN
admet-189	307	12	nanotechnology	nanotechnology	NOUN
admet-189	307	13	based	base	VERB
admet-189	307	14	active	active	ADJ
admet-189	307	15	targeting	targeting	NOUN
admet-189	307	16	plays	play	VERB
admet-189	307	17	a	a	DET
admet-189	307	18	crucial	crucial	ADJ
admet-189	307	19	role	role	NOUN
admet-189	307	20	in	in	ADP
admet-189	307	21	directing	direct	VERB
admet-189	307	22	the	the	DET
admet-189	307	23	neurotherapeutics	neurotherapeutic	NOUN
admet-189	307	24	at	at	ADP
admet-189	307	25	the	the	DET
admet-189	307	26	target	target	NOUN
admet-189	307	27	site	site	NOUN
admet-189	307	28	through	through	ADP
admet-189	307	29	specific	specific	ADJ
admet-189	307	30	pathways	pathway	NOUN
admet-189	307	31	.	.	PUNCT
admet-189	308	1	nanoparticles	nanoparticle	NOUN
admet-189	308	2	are	be	AUX
admet-189	308	3	surface	surface	NOUN
admet-189	308	4	functionalized	functionalize	VERB
admet-189	308	5	/	/	SYM
admet-189	308	6	modified	modify	VERB
admet-189	308	7	with	with	ADP
admet-189	308	8	specific	specific	ADJ
admet-189	308	9	ligands	ligand	NOUN
admet-189	308	10	like	like	ADP
admet-189	308	11	peptides	peptide	NOUN
admet-189	308	12	(	(	PUNCT
admet-189	308	13	insulin	insulin	NOUN
admet-189	308	14	,	,	PUNCT
admet-189	308	15	insulin	insulin	NOUN
admet-189	308	16	like	like	ADP
admet-189	308	17	growth	growth	NOUN
admet-189	308	18	factor	factor	NOUN
admet-189	308	19	)	)	PUNCT
admet-189	308	20	,	,	PUNCT
admet-189	308	21	antibodies	antibodie	VERB
admet-189	308	22	or	or	CCONJ
admet-189	308	23	antigens	antigen	NOUN
admet-189	308	24	for	for	ADP
admet-189	308	25	receptors	receptor	NOUN
admet-189	308	26	/	/	SYM
admet-189	308	27	transporters	transporter	NOUN
admet-189	308	28	that	that	PRON
admet-189	308	29	are	be	AUX
admet-189	308	30	expressed	express	VERB
admet-189	308	31	on	on	ADP
admet-189	308	32	bbb	bbb	PROPN
admet-189	308	33	therefore	therefore	ADV
admet-189	308	34	,	,	PUNCT
admet-189	308	35	facilitating	facilitate	VERB
admet-189	308	36	enhanced	enhanced	ADJ
admet-189	308	37	bioavailability	bioavailability	NOUN
admet-189	308	38	through	through	ADP
admet-189	308	39	receptor	receptor	NOUN
admet-189	308	40	mediated	mediate	VERB
admet-189	308	41	endocytosis	endocytosis	NOUN
admet-189	308	42	into	into	ADP
admet-189	308	43	the	the	DET
admet-189	308	44	brain	brain	NOUN
admet-189	308	45	.	.	PUNCT
admet-189	309	1	the	the	DET
admet-189	309	2	peptidomimetic	peptidomimetic	ADJ
admet-189	309	3	antibodies	antibody	NOUN
admet-189	309	4	decorated	decorate	VERB
admet-189	309	5	on	on	ADP
admet-189	309	6	nanoparticles	nanoparticle	NOUN
admet-189	309	7	can	can	AUX
admet-189	309	8	be	be	AUX
admet-189	309	9	used	use	VERB
admet-189	309	10	as	as	ADP
admet-189	309	11	molecular	molecular	ADJ
admet-189	309	12	trojan	trojan	NOUN
admet-189	309	13	horses	horse	NOUN
admet-189	309	14	to	to	PART
admet-189	309	15	ferry	ferry	VERB
admet-189	309	16	large	large	ADJ
admet-189	309	17	molecules	molecule	NOUN
admet-189	309	18	like	like	ADP
admet-189	309	19	drugs	drug	NOUN
admet-189	309	20	and	and	CCONJ
admet-189	309	21	genes	gene	NOUN
admet-189	309	22	across	across	ADP
admet-189	309	23	the	the	DET
admet-189	309	24	bbb	bbb	NOUN
admet-189	310	1	[	[	X
admet-189	310	2	74,75	74,75	NUM
admet-189	310	3	]	]	PUNCT
admet-189	310	4	.	.	PUNCT
admet-189	311	1	previous	previous	ADJ
admet-189	311	2	studies	study	NOUN
admet-189	311	3	showed	show	VERB
admet-189	311	4	expression	expression	NOUN
admet-189	311	5	of	of	ADP
admet-189	311	6	different	different	ADJ
admet-189	311	7	receptors	receptor	NOUN
admet-189	311	8	mainly	mainly	ADV
admet-189	311	9	low	low	ADJ
admet-189	311	10	-	-	PUNCT
admet-189	311	11	density	density	NOUN
admet-189	311	12	lipoprotein	lipoprotein	ADJ
admet-189	311	13	(	(	PUNCT
admet-189	311	14	ldl	ldl	NOUN
admet-189	311	15	)	)	PUNCT
admet-189	311	16	and	and	CCONJ
admet-189	311	17	low	low	ADJ
admet-189	311	18	density	density	NOUN
admet-189	311	19	lipoprotein	lipoprotein	X
admet-189	311	20	related	relate	VERB
admet-189	311	21	protein-1	protein-1	PROPN
admet-189	311	22	and	and	CCONJ
admet-189	311	23	2	2	NUM
admet-189	311	24	(	(	PUNCT
admet-189	311	25	lrp-1,2	lrp-1,2	ADJ
admet-189	311	26	)	)	PUNCT
admet-189	311	27	transferrin	transferrin	NOUN
admet-189	311	28	,	,	PUNCT
admet-189	311	29	p	p	NOUN
admet-189	311	30	-	-	PUNCT
admet-189	311	31	gp	gp	NOUN
admet-189	311	32	efflux	efflux	NOUN
admet-189	311	33	transporter	transporter	NOUN
admet-189	311	34	on	on	ADP
admet-189	311	35	bbb	bbb	PROPN
admet-189	312	1	[	[	X
admet-189	312	2	76	76	NUM
admet-189	312	3	]	]	PUNCT
admet-189	312	4	.	.	PUNCT
admet-189	313	1	the	the	DET
admet-189	313	2	receptor	receptor	NOUN
admet-189	313	3	mediated	mediate	VERB
admet-189	313	4	endocytosis	endocytosis	NOUN
admet-189	313	5	involves	involve	VERB
admet-189	313	6	ligand	ligand	NOUN
admet-189	313	7	-	-	PUNCT
admet-189	313	8	receptor	receptor	NOUN
admet-189	313	9	interaction	interaction	NOUN
admet-189	313	10	resulting	result	VERB
admet-189	313	11	in	in	ADP
admet-189	313	12	endocytosis	endocytosis	NOUN
admet-189	313	13	at	at	ADP
admet-189	313	14	the	the	DET
admet-189	313	15	luminal	luminal	ADJ
admet-189	313	16	side	side	NOUN
admet-189	313	17	of	of	ADP
admet-189	313	18	bbb	bbb	PROPN
admet-189	313	19	followed	follow	VERB
admet-189	313	20	by	by	ADP
admet-189	313	21	translocation	translocation	NOUN
admet-189	313	22	through	through	ADP
admet-189	313	23	the	the	DET
admet-189	313	24	endothelial	endothelial	ADJ
admet-189	313	25	cytoplasm	cytoplasm	NOUN
admet-189	313	26	to	to	ADP
admet-189	313	27	the	the	DET
admet-189	313	28	abluminal	abluminal	ADJ
admet-189	313	29	side	side	NOUN
admet-189	313	30	and	and	CCONJ
admet-189	313	31	finally	finally	ADV
admet-189	313	32	exocytosis	exocytosis	NOUN
admet-189	313	33	allowing	allow	VERB
admet-189	313	34	release	release	NOUN
admet-189	313	35	of	of	ADP
admet-189	313	36	payload	payload	NOUN
admet-189	313	37	at	at	ADP
admet-189	313	38	the	the	DET
admet-189	313	39	target	target	NOUN
admet-189	313	40	site	site	NOUN
admet-189	313	41	[	[	X
admet-189	313	42	77	77	NUM
admet-189	313	43	]	]	PUNCT
admet-189	313	44	.	.	PUNCT
admet-189	314	1	the	the	DET
admet-189	314	2	payloads	payload	NOUN
admet-189	314	3	may	may	AUX
admet-189	314	4	be	be	AUX
admet-189	314	5	in	in	ADP
admet-189	314	6	the	the	DET
admet-189	314	7	form	form	NOUN
admet-189	314	8	of	of	ADP
admet-189	314	9	a	a	DET
admet-189	314	10	drug	drug	NOUN
admet-189	314	11	or	or	CCONJ
admet-189	314	12	a	a	DET
admet-189	314	13	gene	gene	NOUN
admet-189	314	14	.	.	PUNCT
admet-189	315	1	gene	gene	NOUN
admet-189	315	2	therapy	therapy	NOUN
admet-189	315	3	is	be	AUX
admet-189	315	4	becoming	become	VERB
admet-189	315	5	a	a	DET
admet-189	315	6	popular	popular	ADJ
admet-189	315	7	approach	approach	NOUN
admet-189	315	8	to	to	PART
admet-189	315	9	treat	treat	VERB
admet-189	315	10	pd	pd	PROPN
admet-189	315	11	with	with	ADP
admet-189	315	12	some	some	DET
admet-189	315	13	drawbacks	drawback	NOUN
admet-189	315	14	in	in	ADP
admet-189	315	15	currently	currently	ADV
admet-189	315	16	available	available	ADJ
admet-189	315	17	therapies	therapy	NOUN
admet-189	315	18	like	like	ADP
admet-189	315	19	poor	poor	ADJ
admet-189	315	20	permeability	permeability	NOUN
admet-189	315	21	of	of	ADP
admet-189	315	22	the	the	DET
admet-189	315	23	gene	gene	NOUN
admet-189	315	24	vector	vector	NOUN
admet-189	315	25	across	across	ADP
admet-189	315	26	the	the	DET
admet-189	315	27	bbb	bbb	NOUN
admet-189	315	28	after	after	ADP
admet-189	315	29	intravenous	intravenous	ADJ
admet-189	315	30	administration	administration	NOUN
admet-189	315	31	which	which	PRON
admet-189	315	32	limits	limit	VERB
admet-189	315	33	the	the	DET
admet-189	315	34	therapeutic	therapeutic	ADJ
admet-189	315	35	efficacy	efficacy	NOUN
admet-189	315	36	.	.	PUNCT
admet-189	316	1	local	local	ADJ
admet-189	316	2	intracerebral	intracerebral	ADJ
admet-189	316	3	administration	administration	NOUN
admet-189	316	4	of	of	ADP
admet-189	316	5	the	the	DET
admet-189	316	6	gene	gene	NOUN
admet-189	316	7	vector	vector	NOUN
admet-189	316	8	at	at	ADP
admet-189	316	9	the	the	DET
admet-189	316	10	target	target	NOUN
admet-189	316	11	site	site	NOUN
admet-189	316	12	is	be	AUX
admet-189	316	13	often	often	ADV
admet-189	316	14	limited	limit	VERB
admet-189	316	15	by	by	ADP
admet-189	316	16	lack	lack	NOUN
admet-189	316	17	of	of	ADP
admet-189	316	18	patient	patient	ADJ
admet-189	316	19	compliance	compliance	NOUN
admet-189	316	20	due	due	ADP
admet-189	316	21	to	to	ADP
admet-189	316	22	high	high	ADJ
admet-189	316	23	invasiveness	invasiveness	ADJ
admet-189	316	24	and	and	CCONJ
admet-189	316	25	repetitive	repetitive	ADJ
admet-189	316	26	injection	injection	NOUN
admet-189	316	27	schedule	schedule	NOUN
admet-189	316	28	.	.	PUNCT
admet-189	317	1	schlachetzki	schlachetzki	NOUN
admet-189	317	2	and	and	CCONJ
admet-189	317	3	colleagues	colleague	NOUN
admet-189	317	4	discussed	discuss	VERB
admet-189	317	5	trans	trans	ADJ
admet-189	317	6	-	-	ADJ
admet-189	317	7	vascular	vascular	ADJ
admet-189	317	8	delivery	delivery	NOUN
admet-189	317	9	,	,	PUNCT
admet-189	317	10	a	a	DET
admet-189	317	11	novel	novel	ADJ
admet-189	317	12	approach	approach	NOUN
admet-189	317	13	for	for	ADP
admet-189	317	14	gene	gene	NOUN
admet-189	317	15	therapy	therapy	NOUN
admet-189	317	16	to	to	ADP
admet-189	317	17	the	the	DET
admet-189	317	18	brain	brain	NOUN
admet-189	317	19	using	use	VERB
admet-189	317	20	targeted	target	VERB
admet-189	317	21	nano	nano	NOUN
admet-189	317	22	-	-	PUNCT
admet-189	317	23	carriers	carrier	NOUN
admet-189	317	24	[	[	X
admet-189	317	25	74	74	NUM
admet-189	317	26	]	]	PUNCT
admet-189	317	27	.	.	PUNCT
admet-189	318	1	this	this	DET
admet-189	318	2	approach	approach	NOUN
admet-189	318	3	can	can	AUX
admet-189	318	4	be	be	AUX
admet-189	318	5	of	of	ADP
admet-189	318	6	two	two	NUM
admet-189	318	7	typesthe	typesthe	ADV
admet-189	318	8	more	more	ADV
admet-189	318	9	invasive	invasive	ADJ
admet-189	318	10	one	one	NUM
admet-189	318	11	involves	involve	VERB
admet-189	318	12	bbb	bbb	NOUN
admet-189	318	13	disruption	disruption	NOUN
admet-189	318	14	,	,	PUNCT
admet-189	318	15	using	use	VERB
admet-189	318	16	the	the	DET
admet-189	318	17	intracarotid	intracarotid	NOUN
admet-189	318	18	infusion	infusion	NOUN
admet-189	318	19	of	of	ADP
admet-189	318	20	vasoactive	vasoactive	ADJ
admet-189	318	21	compounds	compound	NOUN
admet-189	318	22	or	or	CCONJ
admet-189	318	23	hyperosmolar	hyperosmolar	ADJ
admet-189	318	24	solutions	solution	NOUN
admet-189	318	25	and	and	CCONJ
admet-189	318	26	the	the	DET
admet-189	318	27	less	less	ADV
admet-189	318	28	invasive	invasive	ADJ
admet-189	318	29	one	one	NUM
admet-189	318	30	involves	involve	VERB
admet-189	318	31	the	the	DET
admet-189	318	32	targeting	targeting	NOUN
admet-189	318	33	of	of	ADP
admet-189	318	34	certain	certain	ADJ
admet-189	318	35	endogenous	endogenous	ADJ
admet-189	318	36	transport	transport	NOUN
admet-189	318	37	systems	system	NOUN
admet-189	318	38	within	within	ADP
admet-189	318	39	the	the	DET
admet-189	318	40	bbb	bbb	PROPN
admet-189	318	41	.	.	PUNCT
admet-189	319	1	as	as	ADP
admet-189	319	2	an	an	DET
admet-189	319	3	example	example	NOUN
admet-189	319	4	of	of	ADP
admet-189	319	5	the	the	DET
admet-189	319	6	latter	latter	ADJ
admet-189	319	7	,	,	PUNCT
admet-189	319	8	zhang	zhang	PROPN
admet-189	319	9	et	et	PROPN
admet-189	319	10	al	al	PROPN
admet-189	319	11	.	.	PROPN
admet-189	319	12	delivered	deliver	VERB
admet-189	319	13	tyrosine	tyrosine	NOUN
admet-189	319	14	hydroxylase	hydroxylase	NOUN
admet-189	319	15	gene	gene	NOUN
admet-189	319	16	to	to	ADP
admet-189	319	17	the	the	DET
admet-189	319	18	brain	brain	NOUN
admet-189	319	19	using	use	VERB
admet-189	319	20	a	a	DET
admet-189	319	21	pegylated	pegylate	VERB
admet-189	319	22	immunoliposome	immunoliposome	NOUN
admet-189	319	23	system	system	NOUN
admet-189	319	24	with	with	ADP
admet-189	319	25	a	a	DET
admet-189	319	26	targeting	target	VERB
admet-189	319	27	moiety	moiety	NOUN
admet-189	319	28	in	in	ADP
admet-189	319	29	the	the	DET
admet-189	319	30	form	form	NOUN
admet-189	319	31	of	of	ADP
admet-189	319	32	a	a	DET
admet-189	319	33	murine	murine	ADJ
admet-189	319	34	monoclonal	monoclonal	NOUN
admet-189	319	35	antibody	antibody	NOUN
admet-189	319	36	(	(	PUNCT
admet-189	319	37	mab	mab	PROPN
admet-189	319	38	)	)	PUNCT
admet-189	319	39	to	to	ADP
admet-189	319	40	the	the	DET
admet-189	319	41	rat	rat	NOUN
admet-189	319	42	transferrin	transferrin	NOUN
admet-189	319	43	receptor	receptor	NOUN
admet-189	320	1	[	[	X
admet-189	320	2	78	78	NUM
admet-189	320	3	]	]	PUNCT
admet-189	320	4	.	.	PUNCT
admet-189	321	1	receptors	receptor	NOUN
admet-189	321	2	like	like	ADP
admet-189	321	3	transferrin	transferrin	NOUN
admet-189	321	4	play	play	VERB
admet-189	321	5	an	an	DET
admet-189	321	6	important	important	ADJ
admet-189	321	7	role	role	NOUN
admet-189	321	8	in	in	ADP
admet-189	321	9	transporting	transport	VERB
admet-189	321	10	iron	iron	NOUN
admet-189	321	11	to	to	ADP
admet-189	321	12	the	the	DET
admet-189	321	13	brain	brain	NOUN
admet-189	321	14	through	through	ADP
admet-189	321	15	receptor	receptor	NOUN
admet-189	321	16	mediated	mediate	VERB
admet-189	321	17	endocytosis	endocytosis	NOUN
admet-189	321	18	.	.	PUNCT
admet-189	322	1	the	the	DET
admet-189	322	2	technology	technology	NOUN
admet-189	322	3	functions	function	NOUN
admet-189	322	4	as	as	ADP
admet-189	322	5	a	a	DET
admet-189	322	6	trojan	trojan	NOUN
admet-189	322	7	horse	horse	NOUN
admet-189	322	8	to	to	PART
admet-189	322	9	ferry	ferry	VERB
admet-189	322	10	the	the	DET
admet-189	322	11	gene	gene	NOUN
admet-189	322	12	across	across	ADP
admet-189	322	13	the	the	DET
admet-189	322	14	bbb	bbb	NOUN
admet-189	322	15	and	and	CCONJ
admet-189	322	16	demonstrated	demonstrate	VERB
admet-189	322	17	reversible	reversible	ADJ
admet-189	322	18	normalization	normalization	NOUN
admet-189	322	19	of	of	ADP
admet-189	322	20	tyrosine	tyrosine	NOUN
admet-189	322	21	hydroxylase	hydroxylase	NOUN
admet-189	322	22	(	(	PUNCT
admet-189	322	23	th	th	NOUN
admet-189	322	24	)	)	PUNCT
admet-189	322	25	activity	activity	NOUN
admet-189	322	26	in	in	ADP
admet-189	322	27	the	the	DET
admet-189	322	28	striatum	striatum	NOUN
admet-189	322	29	along	along	ADP
admet-189	322	30	with	with	ADP
admet-189	322	31	favorable	favorable	ADJ
admet-189	322	32	behavioral	behavioral	ADJ
admet-189	322	33	effects	effect	NOUN
admet-189	322	34	in	in	ADP
admet-189	322	35	experimental	experimental	ADJ
admet-189	322	36	models	model	NOUN
admet-189	322	37	of	of	ADP
admet-189	322	38	parkinsonism	parkinsonism	NOUN
admet-189	322	39	in	in	ADP
admet-189	322	40	rats	rat	NOUN
admet-189	322	41	[	[	X
admet-189	322	42	78	78	NUM
admet-189	322	43	]	]	PUNCT
admet-189	322	44	.	.	PUNCT
admet-189	323	1	carroll	carroll	PROPN
admet-189	323	2	and	and	CCONJ
admet-189	323	3	colleagues	colleague	NOUN
admet-189	323	4	(	(	PUNCT
admet-189	323	5	2010	2010	NUM
admet-189	323	6	)	)	PUNCT
admet-189	323	7	have	have	AUX
admet-189	323	8	reported	report	VERB
admet-189	323	9	the	the	DET
admet-189	323	10	transferrin	transferrin	NOUN
admet-189	323	11	receptor	receptor	NOUN
admet-189	323	12	antibody	antibody	NOUN
admet-189	323	13	(	(	PUNCT
admet-189	323	14	ox26	ox26	PROPN
admet-189	323	15	)	)	PUNCT
admet-189	323	16	conjugated	conjugate	VERB
admet-189	323	17	plga	plga	NOUN
admet-189	323	18	nanoparticles	nanoparticle	NOUN
admet-189	323	19	loaded	load	VERB
admet-189	323	20	with	with	ADP
admet-189	323	21	antioxidant	antioxidant	NOUN
admet-189	323	22	has	have	VERB
admet-189	323	23	significant	significant	ADJ
admet-189	323	24	potential	potential	NOUN
admet-189	323	25	against	against	ADP
admet-189	323	26	oxidative	oxidative	ADJ
admet-189	323	27	stress	stress	NOUN
admet-189	323	28	induced	induce	VERB
admet-189	323	29	neurodegenerative	neurodegenerative	ADJ
admet-189	323	30	diseases	disease	NOUN
admet-189	323	31	[	[	X
admet-189	323	32	79	79	NUM
admet-189	323	33	]	]	PUNCT
admet-189	323	34	.	.	PUNCT
admet-189	324	1	the	the	DET
admet-189	324	2	in	in	ADV
admet-189	324	3	vitro	vitro	X
admet-189	324	4	study	study	NOUN
admet-189	324	5	showed	show	VERB
admet-189	324	6	higher	high	ADJ
admet-189	324	7	cellular	cellular	ADJ
admet-189	324	8	uptake	uptake	NOUN
admet-189	324	9	and	and	CCONJ
admet-189	324	10	decreased	decrease	VERB
admet-189	324	11	cell	cell	NOUN
admet-189	324	12	viability	viability	NOUN
admet-189	324	13	of	of	ADP
admet-189	324	14	rg2	rg2	NOUN
admet-189	324	15	rat	rat	NOUN
admet-189	324	16	glioma	glioma	NOUN
admet-189	324	17	cells	cell	NOUN
admet-189	324	18	with	with	ADP
admet-189	324	19	targeted	target	VERB
admet-189	324	20	nanoparticles	nanoparticle	NOUN
admet-189	324	21	as	as	SCONJ
admet-189	324	22	compared	compare	VERB
admet-189	324	23	to	to	ADP
admet-189	324	24	nontargeted	nontargete	VERB
admet-189	324	25	nanoparticles	nanoparticle	NOUN
admet-189	324	26	through	through	ADP
admet-189	324	27	receptor	receptor	NOUN
admet-189	324	28	mediated	mediate	VERB
admet-189	324	29	endocytosis	endocytosis	NOUN
admet-189	324	30	.	.	PUNCT
admet-189	325	1	these	these	DET
admet-189	325	2	findings	finding	NOUN
admet-189	325	3	suggest	suggest	VERB
admet-189	325	4	the	the	DET
admet-189	325	5	potential	potential	NOUN
admet-189	325	6	of	of	ADP
admet-189	325	7	transferrin	transferrin	ADJ
admet-189	325	8	receptor	receptor	NOUN
admet-189	325	9	in	in	ADP
admet-189	325	10	the	the	DET
admet-189	325	11	treatment	treatment	NOUN
admet-189	325	12	of	of	ADP
admet-189	325	13	other	other	ADJ
admet-189	325	14	neurodegenerative	neurodegenerative	ADJ
admet-189	325	15	diseases	disease	NOUN
admet-189	325	16	mediating	mediate	VERB
admet-189	325	17	the	the	DET
admet-189	325	18	transport	transport	NOUN
admet-189	325	19	of	of	ADP
admet-189	325	20	drug	drug	NOUN
admet-189	325	21	across	across	ADP
admet-189	325	22	bbb	bbb	PROPN
admet-189	325	23	[	[	X
admet-189	325	24	79	79	NUM
admet-189	325	25	]	]	PUNCT
admet-189	325	26	.	.	PUNCT
admet-189	326	1	lactoferrin	lactoferrin	PROPN
admet-189	326	2	is	be	AUX
admet-189	326	3	a	a	DET
admet-189	326	4	cationic	cationic	ADJ
admet-189	326	5	iron	iron	NOUN
admet-189	326	6	binding	bind	VERB
admet-189	326	7	glycoprotein	glycoprotein	NOUN
admet-189	326	8	from	from	ADP
admet-189	326	9	one	one	NUM
admet-189	326	10	of	of	ADP
admet-189	326	11	the	the	DET
admet-189	326	12	transferrin	transferrin	NOUN
admet-189	326	13	receptor	receptor	NOUN
admet-189	326	14	family	family	NOUN
admet-189	326	15	.	.	PUNCT
admet-189	327	1	previous	previous	ADJ
admet-189	327	2	studies	study	NOUN
admet-189	327	3	on	on	ADP
admet-189	327	4	lactoferrin	lactoferrin	NOUN
admet-189	327	5	receptors	receptor	NOUN
admet-189	327	6	reported	report	VERB
admet-189	327	7	that	that	SCONJ
admet-189	327	8	their	their	PRON
admet-189	327	9	expression	expression	NOUN
admet-189	327	10	on	on	ADP
admet-189	327	11	bbb	bbb	PROPN
admet-189	327	12	facilitates	facilitate	VERB
admet-189	327	13	the	the	DET
admet-189	327	14	transport	transport	NOUN
admet-189	327	15	of	of	ADP
admet-189	327	16	lactoferrin	lactoferrin	NOUN
admet-189	327	17	to	to	ADP
admet-189	327	18	the	the	DET
admet-189	327	19	brain	brain	NOUN
admet-189	328	1	[	[	X
admet-189	328	2	80	80	NUM
admet-189	328	3	]	]	PUNCT
admet-189	328	4	.	.	PUNCT
admet-189	329	1	ji	ji	PROPN
admet-189	329	2	and	and	CCONJ
admet-189	329	3	colleagues	colleague	NOUN
admet-189	329	4	in	in	ADP
admet-189	329	5	2006	2006	NUM
admet-189	329	6	have	have	AUX
admet-189	329	7	demonstrated	demonstrate	VERB
admet-189	329	8	the	the	DET
admet-189	329	9	greater	great	ADJ
admet-189	329	10	brain	brain	NOUN
admet-189	329	11	uptake	uptake	NOUN
admet-189	329	12	of	of	ADP
admet-189	329	13	lactotransferrin	lactotransferrin	NOUN
admet-189	329	14	than	than	ADP
admet-189	329	15	that	that	PRON
admet-189	329	16	of	of	ADP
admet-189	329	17	transferrin	transferrin	NOUN
admet-189	329	18	and	and	CCONJ
admet-189	329	19	ox26	ox26	PROPN
admet-189	329	20	(	(	PUNCT
admet-189	329	21	an	an	DET
admet-189	329	22	anti	anti	ADJ
admet-189	329	23	-	-	ADJ
admet-189	329	24	transferrin	transferrin	ADJ
admet-189	329	25	receptor	receptor	NOUN
admet-189	329	26	antibody	antibody	NOUN
admet-189	329	27	)	)	PUNCT
admet-189	329	28	through	through	ADP
admet-189	329	29	endocytosis	endocytosis	NOUN
admet-189	329	30	mediated	mediate	VERB
admet-189	329	31	by	by	ADP
admet-189	329	32	receptors	receptor	NOUN
admet-189	329	33	in	in	ADP
admet-189	329	34	an	an	DET
admet-189	329	35	in	in	ADP
admet-189	329	36	vitro	vitro	X
admet-189	329	37	bbb	bbb	PROPN
admet-189	329	38	study	study	NOUN
admet-189	329	39	.	.	PUNCT
admet-189	330	1	[	[	X
admet-189	330	2	81].using	81].using	NOUN
admet-189	330	3	this	this	DET
admet-189	330	4	concept	concept	NOUN
admet-189	330	5	,	,	PUNCT
admet-189	330	6	hu	hu	PROPN
admet-189	330	7	et	et	PROPN
admet-189	330	8	al	al	PROPN
admet-189	330	9	.	.	PROPN
admet-189	331	1	in	in	ADP
admet-189	331	2	2009	2009	NUM
admet-189	331	3	demonstrated	demonstrate	VERB
admet-189	331	4	the	the	DET
admet-189	331	5	improved	improved	ADJ
admet-189	331	6	brain	brain	NOUN
admet-189	331	7	targeting	target	VERB
admet-189	331	8	potential	potential	NOUN
admet-189	331	9	of	of	ADP
admet-189	331	10	lactoferrin	lactoferrin	NOUN
admet-189	331	11	conjugated	conjugate	VERB
admet-189	331	12	plga	plga	NOUN
admet-189	331	13	nanoparticles	nanoparticle	NOUN
admet-189	331	14	as	as	ADP
admet-189	331	15	r.	r.	PROPN
admet-189	331	16	banerjee	banerjee	PROPN
admet-189	331	17	et	et	PROPN
admet-189	331	18	al	al	PROPN
admet-189	331	19	.	.	PROPN
admet-189	331	20	admet	admet	PROPN
admet-189	331	21	&	&	CCONJ
admet-189	331	22	dmpk	dmpk	PROPN
admet-189	331	23	3(3	3(3	NUM
admet-189	331	24	)	)	PUNCT
admet-189	331	25	(	(	PUNCT
admet-189	331	26	2015	2015	NUM
admet-189	331	27	)	)	PUNCT
admet-189	331	28	155	155	NUM
admet-189	331	29	-	-	SYM
admet-189	331	30	181	181	NUM
admet-189	331	31	166	166	NUM
admet-189	331	32	compared	compare	VERB
admet-189	331	33	to	to	ADP
admet-189	331	34	unmodified	unmodified	ADJ
admet-189	331	35	nanoparticles	nanoparticle	NOUN
admet-189	331	36	[	[	X
admet-189	331	37	81	81	NUM
admet-189	331	38	]	]	PUNCT
admet-189	331	39	.	.	PUNCT
admet-189	332	1	here	here	ADV
admet-189	332	2	lactoferrin	lactoferrin	NOUN
admet-189	332	3	acts	act	VERB
admet-189	332	4	as	as	ADP
admet-189	332	5	the	the	DET
admet-189	332	6	ferrying	ferry	VERB
admet-189	332	7	moiety	moiety	NOUN
admet-189	332	8	across	across	ADP
admet-189	332	9	the	the	DET
admet-189	332	10	bbb	bbb	NOUN
admet-189	332	11	to	to	PART
admet-189	332	12	allow	allow	VERB
admet-189	332	13	the	the	DET
admet-189	332	14	trojan	trojan	NOUN
admet-189	332	15	horselike	horselike	ADJ
admet-189	332	16	delivery	delivery	NOUN
admet-189	332	17	of	of	ADP
admet-189	332	18	payloads	payload	NOUN
admet-189	332	19	[	[	X
admet-189	332	20	81	81	NUM
admet-189	332	21	]	]	PUNCT
admet-189	332	22	.	.	PUNCT
admet-189	333	1	this	this	DET
admet-189	333	2	finding	finding	NOUN
admet-189	333	3	showed	show	VERB
admet-189	333	4	higher	high	ADJ
admet-189	333	5	brain	brain	NOUN
admet-189	333	6	uptake	uptake	NOUN
admet-189	333	7	(	(	PUNCT
admet-189	333	8	3	3	NUM
admet-189	333	9	-	-	NOUN
admet-189	333	10	fold	fold	ADJ
admet-189	333	11	)	)	PUNCT
admet-189	333	12	of	of	ADP
admet-189	333	13	lactoferrin	lactoferrin	ADJ
admet-189	333	14	modified	modify	VERB
admet-189	333	15	nanoparticles	nanoparticle	NOUN
admet-189	333	16	in	in	ADP
admet-189	333	17	mice	mouse	NOUN
admet-189	333	18	over	over	ADP
admet-189	333	19	non	non	ADJ
admet-189	333	20	-	-	ADJ
admet-189	333	21	modified	modified	ADJ
admet-189	333	22	nanoparticles	nanoparticle	NOUN
admet-189	333	23	[	[	X
admet-189	333	24	81	81	NUM
admet-189	333	25	]	]	PUNCT
admet-189	333	26	.	.	PUNCT
admet-189	334	1	interestingly	interestingly	ADV
admet-189	334	2	,	,	PUNCT
admet-189	334	3	in	in	ADP
admet-189	334	4	2011	2011	NUM
admet-189	334	5	,	,	PUNCT
admet-189	334	6	hu	hu	PROPN
admet-189	334	7	et	et	PROPN
admet-189	334	8	al	al	PROPN
admet-189	334	9	.	.	PROPN
admet-189	334	10	;	;	PUNCT
admet-189	334	11	further	far	ADV
admet-189	334	12	demonstrated	demonstrate	VERB
admet-189	334	13	the	the	DET
admet-189	334	14	successful	successful	ADJ
admet-189	334	15	brain	brain	NOUN
admet-189	334	16	delivery	delivery	NOUN
admet-189	334	17	of	of	ADP
admet-189	334	18	urocortin	urocortin	NOUN
admet-189	334	19	(	(	PUNCT
admet-189	334	20	corticotrophin	corticotrophin	NOUN
admet-189	334	21	releasing	release	VERB
admet-189	334	22	hormone	hormone	NOUN
admet-189	334	23	related	relate	VERB
admet-189	334	24	peptide	peptide	NOUN
admet-189	334	25	)	)	PUNCT
admet-189	334	26	loaded	load	VERB
admet-189	334	27	lactoferrin	lactoferrin	NOUN
admet-189	334	28	conjugated	conjugate	VERB
admet-189	334	29	polyethylene	polyethylene	NOUN
admet-189	334	30	glycol	glycol	NOUN
admet-189	334	31	-	-	PUNCT
admet-189	334	32	polylactide	polylactide	NOUN
admet-189	334	33	-	-	PUNCT
admet-189	334	34	polyglycolide	polyglycolide	NOUN
admet-189	334	35	(	(	PUNCT
admet-189	334	36	peg	peg	NOUN
admet-189	334	37	-	-	PUNCT
admet-189	334	38	plga	plga	NOUN
admet-189	334	39	)	)	PUNCT
admet-189	334	40	nanoparticles	nanoparticle	NOUN
admet-189	334	41	[	[	X
admet-189	334	42	82	82	NUM
admet-189	334	43	]	]	PUNCT
admet-189	334	44	.	.	PUNCT
admet-189	335	1	in	in	ADP
admet-189	335	2	vivo	vivo	ADJ
admet-189	335	3	pharmacokinetic	pharmacokinetic	ADJ
admet-189	335	4	study	study	NOUN
admet-189	335	5	of	of	ADP
admet-189	335	6	lactoferrin	lactoferrin	NOUN
admet-189	335	7	conjugated	conjugate	VERB
admet-189	335	8	nanoparticles	nanoparticle	NOUN
admet-189	335	9	showed	show	VERB
admet-189	335	10	2.49times	2.49time	NOUN
admet-189	335	11	increase	increase	NOUN
admet-189	335	12	in	in	ADP
admet-189	335	13	auc	auc	NOUN
admet-189	335	14	than	than	ADP
admet-189	335	15	that	that	PRON
admet-189	335	16	of	of	ADP
admet-189	335	17	non	non	ADJ
admet-189	335	18	-	-	ADJ
admet-189	335	19	conjugated	conjugated	ADJ
admet-189	335	20	nanoparticles	nanoparticle	NOUN
admet-189	335	21	in	in	ADP
admet-189	335	22	24h	24h	NOUN
admet-189	335	23	.	.	PUNCT
admet-189	336	1	the	the	DET
admet-189	336	2	in	in	ADV
admet-189	336	3	vitro	vitro	X
admet-189	336	4	cellular	cellular	ADJ
admet-189	336	5	study	study	NOUN
admet-189	336	6	on	on	ADP
admet-189	336	7	immortalized	immortalized	ADJ
admet-189	336	8	mouse	mouse	NOUN
admet-189	336	9	brain	brain	NOUN
admet-189	336	10	endothelial	endothelial	ADJ
admet-189	336	11	cell	cell	NOUN
admet-189	336	12	line	line	NOUN
admet-189	336	13	(	(	PUNCT
admet-189	336	14	b.end3	b.end3	PROPN
admet-189	336	15	)	)	PUNCT
admet-189	336	16	revealed	reveal	VERB
admet-189	336	17	that	that	SCONJ
admet-189	336	18	the	the	DET
admet-189	336	19	uptake	uptake	NOUN
admet-189	336	20	of	of	ADP
admet-189	336	21	conjugated	conjugated	ADJ
admet-189	336	22	nanoparticles	nanoparticle	NOUN
admet-189	336	23	occurred	occur	VERB
admet-189	336	24	through	through	ADP
admet-189	336	25	clathrin	clathrin	NOUN
admet-189	336	26	mediated	mediate	VERB
admet-189	336	27	endocytosis	endocytosis	NOUN
admet-189	336	28	with	with	ADP
admet-189	336	29	minimal	minimal	ADJ
admet-189	336	30	adverse	adverse	ADJ
admet-189	336	31	effect	effect	NOUN
admet-189	336	32	on	on	ADP
admet-189	336	33	cell	cell	NOUN
admet-189	336	34	viability	viability	NOUN
admet-189	337	1	[	[	X
admet-189	337	2	82	82	NUM
admet-189	337	3	]	]	PUNCT
admet-189	337	4	.	.	PUNCT
admet-189	338	1	further	far	ADV
admet-189	338	2	the	the	DET
admet-189	338	3	conjugated	conjugate	VERB
admet-189	338	4	nanoparticles	nanoparticle	NOUN
admet-189	338	5	showed	show	VERB
admet-189	338	6	significant	significant	ADJ
admet-189	338	7	reduction	reduction	NOUN
admet-189	338	8	of	of	ADP
admet-189	338	9	striatum	striatum	NOUN
admet-189	338	10	lesions	lesion	NOUN
admet-189	338	11	in	in	ADP
admet-189	338	12	6	6	NUM
admet-189	338	13	-	-	PUNCT
admet-189	338	14	ohda	ohda	NOUN
admet-189	338	15	(	(	PUNCT
admet-189	338	16	6hydroxy	6hydroxy	NUM
admet-189	338	17	dopamine	dopamine	NOUN
admet-189	338	18	)	)	PUNCT
admet-189	338	19	induced	induce	VERB
admet-189	338	20	rat	rat	NOUN
admet-189	338	21	pd	pd	PROPN
admet-189	338	22	model	model	NOUN
admet-189	338	23	.	.	PUNCT
admet-189	339	1	together	together	ADV
admet-189	339	2	these	these	DET
admet-189	339	3	findings	finding	NOUN
admet-189	339	4	revealed	reveal	VERB
admet-189	339	5	that	that	SCONJ
admet-189	339	6	lactoferrin	lactoferrin	NOUN
admet-189	339	7	is	be	AUX
admet-189	339	8	a	a	DET
admet-189	339	9	promising	promising	ADJ
admet-189	339	10	targeting	targeting	NOUN
admet-189	339	11	ligand	ligand	NOUN
admet-189	339	12	to	to	PART
admet-189	339	13	enhance	enhance	VERB
admet-189	339	14	targeting	targeting	NOUN
admet-189	339	15	and	and	CCONJ
admet-189	339	16	accumulation	accumulation	NOUN
admet-189	339	17	of	of	ADP
admet-189	339	18	active	active	ADJ
admet-189	339	19	to	to	ADP
admet-189	339	20	brain	brain	NOUN
admet-189	339	21	and	and	CCONJ
admet-189	339	22	lactoferrin	lactoferrin	NOUN
admet-189	339	23	decorated	decorate	VERB
admet-189	339	24	nanoparticles	nanoparticle	NOUN
admet-189	339	25	can	can	AUX
admet-189	339	26	help	help	VERB
admet-189	339	27	to	to	PART
admet-189	339	28	deliver	deliver	VERB
admet-189	339	29	drugs	drug	NOUN
admet-189	339	30	more	more	ADV
admet-189	339	31	effectively	effectively	ADV
admet-189	339	32	in	in	ADP
admet-189	339	33	pd	pd	PROPN
admet-189	339	34	.	.	PUNCT
admet-189	340	1	huang	huang	PROPN
admet-189	340	2	et	et	PROPN
admet-189	340	3	al	al	PROPN
admet-189	340	4	;	;	PUNCT
admet-189	340	5	(	(	PUNCT
admet-189	340	6	2010	2010	NUM
admet-189	340	7	)	)	PUNCT
admet-189	340	8	demonstrated	demonstrate	VERB
admet-189	340	9	long	long	ADJ
admet-189	340	10	term	term	NOUN
admet-189	340	11	,	,	PUNCT
admet-189	340	12	non	non	ADJ
admet-189	340	13	-	-	ADJ
admet-189	340	14	invasive	invasive	ADJ
admet-189	340	15	targeted	target	VERB
admet-189	340	16	gene	gene	NOUN
admet-189	340	17	therapy	therapy	NOUN
admet-189	340	18	in	in	ADP
admet-189	340	19	rotenone	rotenone	NOUN
admet-189	340	20	induced	induce	VERB
admet-189	340	21	chronic	chronic	ADJ
admet-189	340	22	pd	pd	PROPN
admet-189	340	23	model	model	NOUN
admet-189	340	24	using	use	VERB
admet-189	340	25	lactoferrin	lactoferrin	NOUN
admet-189	340	26	functionalized	functionalize	VERB
admet-189	340	27	nanoparticles	nanoparticle	NOUN
admet-189	340	28	encapsulated	encapsulate	VERB
admet-189	340	29	with	with	ADP
admet-189	340	30	human	human	ADJ
admet-189	340	31	glial	glial	ADJ
admet-189	340	32	cell	cell	NOUN
admet-189	340	33	line	line	NOUN
admet-189	340	34	derived	derive	VERB
admet-189	340	35	neurotrophic	neurotrophic	ADJ
admet-189	340	36	factor	factor	NOUN
admet-189	340	37	gene	gene	NOUN
admet-189	340	38	(	(	PUNCT
admet-189	340	39	hgdnf	hgdnf	PROPN
admet-189	340	40	)	)	PUNCT
admet-189	340	41	.	.	PUNCT
admet-189	341	1	the	the	DET
admet-189	341	2	study	study	NOUN
admet-189	341	3	revealed	reveal	VERB
admet-189	341	4	that	that	SCONJ
admet-189	341	5	intravenously	intravenously	ADV
admet-189	341	6	administered	administer	VERB
admet-189	341	7	lactoferrin	lactoferrin	NOUN
admet-189	341	8	decorated	decorate	VERB
admet-189	341	9	nanoparticles	nanoparticle	NOUN
admet-189	341	10	showed	show	VERB
admet-189	341	11	successful	successful	ADJ
admet-189	341	12	gene	gene	NOUN
admet-189	341	13	delivery	delivery	NOUN
admet-189	341	14	to	to	ADP
admet-189	341	15	the	the	DET
admet-189	341	16	brain	brain	NOUN
admet-189	341	17	through	through	ADP
admet-189	341	18	higher	high	ADJ
admet-189	341	19	and	and	CCONJ
admet-189	341	20	long	long	ADV
admet-189	341	21	lasting	last	VERB
admet-189	341	22	gdnf	gdnf	ADJ
admet-189	341	23	expression	expression	NOUN
admet-189	341	24	in	in	ADP
admet-189	341	25	brain	brain	NOUN
admet-189	341	26	in	in	ADP
admet-189	341	27	experimental	experimental	ADJ
admet-189	341	28	animals	animal	NOUN
admet-189	341	29	than	than	ADP
admet-189	341	30	that	that	PRON
admet-189	341	31	of	of	ADP
admet-189	341	32	single	single	ADJ
admet-189	341	33	injection	injection	NOUN
admet-189	341	34	[	[	X
admet-189	341	35	83	83	NUM
admet-189	341	36	]	]	PUNCT
admet-189	341	37	.	.	PUNCT
admet-189	342	1	the	the	DET
admet-189	342	2	lrp-1	lrp-1	PUNCT
admet-189	342	3	and	and	CCONJ
admet-189	342	4	2	2	NUM
admet-189	342	5	receptors	receptor	NOUN
admet-189	342	6	interact	interact	VERB
admet-189	342	7	with	with	ADP
admet-189	342	8	various	various	ADJ
admet-189	342	9	other	other	ADJ
admet-189	342	10	molecules	molecule	NOUN
admet-189	342	11	like	like	ADP
admet-189	342	12	apolipoprotein	apolipoprotein	ADJ
admet-189	342	13	-	-	PUNCT
admet-189	342	14	e	e	NOUN
admet-189	342	15	(	(	PUNCT
admet-189	342	16	apoe	apoe	ADJ
admet-189	342	17	)	)	PUNCT
admet-189	342	18	in	in	ADP
admet-189	342	19	addition	addition	NOUN
admet-189	342	20	to	to	ADP
admet-189	342	21	lactoferrin	lactoferrin	NOUN
admet-189	342	22	and	and	CCONJ
admet-189	342	23	melanotransferrin	melanotransferrin	NOUN
admet-189	342	24	which	which	PRON
admet-189	342	25	have	have	AUX
admet-189	342	26	been	be	AUX
admet-189	342	27	widely	widely	ADV
admet-189	342	28	studied	study	VERB
admet-189	342	29	for	for	ADP
admet-189	342	30	targeting	target	VERB
admet-189	342	31	against	against	ADP
admet-189	342	32	pd	pd	PROPN
admet-189	342	33	.	.	PROPN
admet-189	342	34	wanger	wanger	PROPN
admet-189	342	35	et	et	PROPN
admet-189	342	36	al	al	PROPN
admet-189	342	37	.	.	PROPN
admet-189	343	1	in	in	ADP
admet-189	343	2	2012	2012	NUM
admet-189	343	3	have	have	AUX
admet-189	343	4	reported	report	VERB
admet-189	343	5	the	the	DET
admet-189	343	6	potential	potential	NOUN
admet-189	343	7	of	of	ADP
admet-189	343	8	low	low	ADJ
admet-189	343	9	density	density	NOUN
admet-189	343	10	lipoprotein	lipoprotein	ADJ
admet-189	343	11	receptor	receptor	NOUN
admet-189	343	12	related	relate	VERB
admet-189	343	13	protein	protein	NOUN
admet-189	343	14	(	(	PUNCT
admet-189	343	15	lrp-2	lrp-2	X
admet-189	343	16	)	)	PUNCT
admet-189	343	17	for	for	ADP
admet-189	343	18	specific	specific	ADJ
admet-189	343	19	and	and	CCONJ
admet-189	343	20	effective	effective	ADJ
admet-189	343	21	apolipoprotein	apolipoprotein	ADJ
admet-189	343	22	mediated	mediate	VERB
admet-189	343	23	nanoparticulate	nanoparticulate	ADJ
admet-189	343	24	transport	transport	NOUN
admet-189	343	25	and	and	CCONJ
admet-189	343	26	uptake	uptake	ADJ
admet-189	343	27	by	by	ADP
admet-189	343	28	brain	brain	NOUN
admet-189	343	29	capillary	capillary	ADJ
admet-189	343	30	endothelial	endothelial	NOUN
admet-189	343	31	cells	cell	NOUN
admet-189	343	32	[	[	X
admet-189	343	33	84	84	NUM
admet-189	343	34	]	]	PUNCT
admet-189	343	35	.	.	PUNCT
admet-189	344	1	a	a	DET
admet-189	344	2	brief	brief	ADJ
admet-189	344	3	representation	representation	NOUN
admet-189	344	4	of	of	ADP
admet-189	344	5	the	the	DET
admet-189	344	6	fate	fate	NOUN
admet-189	344	7	of	of	ADP
admet-189	344	8	actively	actively	ADV
admet-189	344	9	targeted	target	VERB
admet-189	344	10	nanoparticles	nanoparticle	NOUN
admet-189	344	11	is	be	AUX
admet-189	344	12	provided	provide	VERB
admet-189	344	13	in	in	ADP
admet-189	344	14	figure	figure	NOUN
admet-189	344	15	3	3	NUM
admet-189	344	16	.	.	PUNCT
admet-189	344	17	figure	figure	NOUN
admet-189	344	18	3	3	NUM
admet-189	344	19	.	.	PUNCT
admet-189	344	20	use	use	NOUN
admet-189	344	21	of	of	ADP
admet-189	344	22	targeted	target	VERB
admet-189	344	23	nanoparticles	nanoparticle	NOUN
admet-189	344	24	for	for	ADP
admet-189	344	25	active	active	ADJ
admet-189	344	26	targeting	targeting	NOUN
admet-189	344	27	in	in	ADP
admet-189	344	28	drug	drug	NOUN
admet-189	344	29	delivery	delivery	NOUN
admet-189	344	30	for	for	ADP
admet-189	344	31	parkinson	parkinson	NOUN
admet-189	344	32	’s	’s	PART
admet-189	344	33	disease	disease	NOUN
admet-189	344	34	admet	admet	PROPN
admet-189	344	35	&	&	CCONJ
admet-189	344	36	dmpk	dmpk	PROPN
admet-189	344	37	3(3	3(3	NUM
admet-189	344	38	)	)	PUNCT
admet-189	344	39	(	(	PUNCT
admet-189	344	40	2015	2015	NUM
admet-189	344	41	)	)	PUNCT
admet-189	344	42	155	155	NUM
admet-189	344	43	-	-	SYM
admet-189	344	44	181	181	NUM
admet-189	344	45	nanotechnology	nanotechnology	NOUN
admet-189	344	46	platforms	platform	NOUN
admet-189	344	47	in	in	ADP
admet-189	344	48	parkinson	parkinson	NOUN
admet-189	344	49	’s	’s	PART
admet-189	344	50	disease	disease	NOUN
admet-189	344	51	doi	doi	NOUN
admet-189	344	52	:	:	PUNCT
admet-189	344	53	10.5599	10.5599	NUM
admet-189	344	54	/	/	SYM
admet-189	344	55	admet.3.3.189	admet.3.3.189	ADP
admet-189	344	56	167	167	NUM
admet-189	344	57	routes	route	NOUN
admet-189	344	58	of	of	ADP
admet-189	344	59	administration	administration	NOUN
admet-189	344	60	to	to	PART
admet-189	344	61	enhance	enhance	VERB
admet-189	344	62	drug	drug	NOUN
admet-189	344	63	delivery	delivery	NOUN
admet-189	344	64	across	across	ADP
admet-189	344	65	bbb	bbb	PROPN
admet-189	344	66	the	the	DET
admet-189	344	67	presence	presence	NOUN
admet-189	344	68	of	of	ADP
admet-189	344	69	the	the	DET
admet-189	344	70	bbb	bbb	PROPN
admet-189	344	71	,	,	PUNCT
admet-189	344	72	limits	limit	VERB
admet-189	344	73	the	the	DET
admet-189	344	74	permeability	permeability	NOUN
admet-189	344	75	of	of	ADP
admet-189	344	76	therapeutic	therapeutic	ADJ
admet-189	344	77	agents	agent	NOUN
admet-189	344	78	to	to	PART
admet-189	344	79	reach	reach	VERB
admet-189	344	80	target	target	NOUN
admet-189	344	81	sites	site	NOUN
admet-189	344	82	in	in	ADP
admet-189	344	83	the	the	DET
admet-189	344	84	cns	cns	NOUN
admet-189	344	85	,	,	PUNCT
admet-189	344	86	resulting	result	VERB
admet-189	344	87	in	in	ADP
admet-189	344	88	insufficient	insufficient	ADJ
admet-189	344	89	bioavailability	bioavailability	NOUN
admet-189	344	90	as	as	ADV
admet-189	344	91	well	well	ADV
admet-189	344	92	as	as	ADP
admet-189	344	93	poor	poor	ADJ
admet-189	344	94	treatment	treatment	NOUN
admet-189	344	95	outcomes	outcome	NOUN
admet-189	344	96	against	against	ADP
admet-189	344	97	neurodegenerative	neurodegenerative	ADJ
admet-189	344	98	disorders	disorder	NOUN
admet-189	344	99	.	.	PUNCT
admet-189	345	1	several	several	ADJ
admet-189	345	2	attempts	attempt	NOUN
admet-189	345	3	have	have	AUX
admet-189	345	4	been	be	AUX
admet-189	345	5	made	make	VERB
admet-189	345	6	for	for	ADP
admet-189	345	7	effective	effective	ADJ
admet-189	345	8	and	and	CCONJ
admet-189	345	9	safe	safe	ADJ
admet-189	345	10	delivery	delivery	NOUN
admet-189	345	11	of	of	ADP
admet-189	345	12	active	active	ADJ
admet-189	345	13	into	into	ADP
admet-189	345	14	the	the	DET
admet-189	345	15	cns	cns	NOUN
admet-189	345	16	.	.	PUNCT
admet-189	346	1	local	local	ADJ
admet-189	346	2	drug	drug	NOUN
admet-189	346	3	delivery	delivery	NOUN
admet-189	346	4	strategies	strategy	NOUN
admet-189	346	5	include	include	VERB
admet-189	346	6	intrathecal	intrathecal	ADJ
admet-189	346	7	,	,	PUNCT
admet-189	346	8	intraparenchymal	intraparenchymal	ADJ
admet-189	346	9	and	and	CCONJ
admet-189	346	10	intracerebral	intracerebral	ADJ
admet-189	346	11	injections	injection	NOUN
admet-189	346	12	directly	directly	ADV
admet-189	346	13	at	at	ADP
admet-189	346	14	the	the	DET
admet-189	346	15	target	target	NOUN
admet-189	346	16	site	site	NOUN
admet-189	346	17	for	for	ADP
admet-189	346	18	transporting	transport	VERB
admet-189	346	19	the	the	DET
admet-189	346	20	therapeutic	therapeutic	ADJ
admet-189	346	21	active	active	ADJ
admet-189	346	22	to	to	ADP
admet-189	346	23	the	the	DET
admet-189	346	24	cns	cns	NOUN
admet-189	346	25	.	.	PUNCT
admet-189	347	1	direct	direct	ADJ
admet-189	347	2	drug	drug	NOUN
admet-189	347	3	delivery	delivery	NOUN
admet-189	347	4	systems	system	NOUN
admet-189	347	5	have	have	VERB
admet-189	347	6	potential	potential	NOUN
admet-189	347	7	to	to	PART
admet-189	347	8	circumvent	circumvent	VERB
admet-189	347	9	the	the	DET
admet-189	347	10	bbb	bbb	PROPN
admet-189	347	11	.	.	PUNCT
admet-189	348	1	pillay	pillay	PROPN
admet-189	348	2	et	et	PROPN
admet-189	348	3	al.(2009	al.(2009	PROPN
admet-189	348	4	)	)	PUNCT
admet-189	348	5	studied	study	VERB
admet-189	348	6	the	the	DET
admet-189	348	7	binary	binary	PROPN
admet-189	348	8	cross	cross	ADJ
admet-189	348	9	-	-	ADJ
admet-189	348	10	linked	link	VERB
admet-189	348	11	alginate	alginate	NOUN
admet-189	348	12	scaffold	scaffold	NOUN
admet-189	348	13	embedded	embed	VERB
admet-189	348	14	polymeric	polymeric	NOUN
admet-189	348	15	(	(	PUNCT
admet-189	348	16	cellulose	cellulose	NOUN
admet-189	348	17	acetate	acetate	NOUN
admet-189	348	18	phthalate	phthalate	NOUN
admet-189	348	19	)	)	PUNCT
admet-189	348	20	nanoparticles	nanoparticle	NOUN
admet-189	348	21	loaded	load	VERB
admet-189	348	22	with	with	ADP
admet-189	348	23	dopamine	dopamine	NOUN
admet-189	348	24	which	which	PRON
admet-189	348	25	after	after	ADP
admet-189	348	26	intracranial	intracranial	ADJ
admet-189	348	27	implantation	implantation	NOUN
admet-189	348	28	showed	show	VERB
admet-189	348	29	enhanced	enhance	VERB
admet-189	348	30	and	and	CCONJ
admet-189	348	31	sustained	sustained	ADJ
admet-189	348	32	dopamine	dopamine	NOUN
admet-189	348	33	delivery	delivery	NOUN
admet-189	348	34	within	within	ADP
admet-189	348	35	csf	csf	NOUN
admet-189	348	36	in	in	ADP
admet-189	348	37	sprague	sprague	NOUN
admet-189	348	38	–	–	PUNCT
admet-189	348	39	dawley	dawley	ADJ
admet-189	348	40	rat	rat	NOUN
admet-189	348	41	model	model	NOUN
admet-189	348	42	with	with	ADP
admet-189	348	43	reduced	reduce	VERB
admet-189	348	44	peripheral	peripheral	ADJ
admet-189	348	45	side	side	NOUN
admet-189	348	46	effects	effect	NOUN
admet-189	348	47	as	as	SCONJ
admet-189	348	48	compared	compare	VERB
admet-189	348	49	to	to	PART
admet-189	348	50	orally	orally	ADV
admet-189	348	51	administered	administer	VERB
admet-189	348	52	l	l	NOUN
admet-189	348	53	-	-	NOUN
admet-189	348	54	dopa	dopa	NOUN
admet-189	348	55	[	[	X
admet-189	348	56	85	85	NUM
admet-189	348	57	]	]	PUNCT
admet-189	348	58	.	.	PUNCT
admet-189	349	1	worly	worly	ADV
admet-189	349	2	et	et	PROPN
admet-189	349	3	al	al	PROPN
admet-189	349	4	.	.	PROPN
admet-189	350	1	(	(	PUNCT
admet-189	350	2	2008	2008	NUM
admet-189	350	3	)	)	PUNCT
admet-189	350	4	developed	develop	VERB
admet-189	350	5	acrylated	acrylate	VERB
admet-189	350	6	3′-sialyllactose	3′-sialyllactose	NUM
admet-189	350	7	(	(	PUNCT
admet-189	350	8	bioactive	bioactive	PROPN
admet-189	350	9	epitope	epitope	NOUN
admet-189	350	10	recognized	recognize	VERB
admet-189	350	11	by	by	ADP
admet-189	350	12	various	various	ADJ
admet-189	350	13	growth	growth	NOUN
admet-189	350	14	factor	factor	NOUN
admet-189	350	15	receptors	receptor	NOUN
admet-189	350	16	like	like	ADP
admet-189	350	17	egfr	egfr	NOUN
admet-189	350	18	)	)	PUNCT
admet-189	350	19	embedded	embed	VERB
admet-189	350	20	within	within	ADP
admet-189	350	21	poly[n-(2	poly[n-(2	NOUN
admet-189	350	22	-	-	PUNCT
admet-189	350	23	hydroxypropyl	hydroxypropyl	NOUN
admet-189	350	24	methacrylamide	methacrylamide	NOUN
admet-189	350	25	)	)	PUNCT
admet-189	350	26	]	]	PUNCT
admet-189	351	1	(	(	PUNCT
admet-189	351	2	phpma	phpma	NOUN
admet-189	351	3	)	)	PUNCT
admet-189	351	4	hydrogels	hydrogel	NOUN
admet-189	351	5	for	for	ADP
admet-189	351	6	intracranial	intracranial	ADJ
admet-189	351	7	implantation	implantation	NOUN
admet-189	351	8	[	[	X
admet-189	351	9	86	86	NUM
admet-189	351	10	]	]	PUNCT
admet-189	351	11	.	.	PUNCT
admet-189	352	1	on	on	ADP
admet-189	352	2	intracranial	intracranial	ADJ
admet-189	352	3	implantation	implantation	NOUN
admet-189	352	4	in	in	ADP
admet-189	352	5	6	6	NUM
admet-189	352	6	-	-	PUNCT
admet-189	352	7	ohda	ohda	NOUN
admet-189	352	8	pd	pd	PROPN
admet-189	352	9	model	model	NOUN
admet-189	352	10	,	,	PUNCT
admet-189	352	11	the	the	DET
admet-189	352	12	hydrogel	hydrogel	NOUN
admet-189	352	13	served	serve	VERB
admet-189	352	14	as	as	ADP
admet-189	352	15	a	a	DET
admet-189	352	16	three	three	NUM
admet-189	352	17	dimensional	dimensional	ADJ
admet-189	352	18	substrate	substrate	NOUN
admet-189	352	19	promoting	promote	VERB
admet-189	352	20	neuronal	neuronal	ADJ
admet-189	352	21	tissue	tissue	NOUN
admet-189	352	22	remodeling	remodeling	NOUN
admet-189	352	23	and	and	CCONJ
admet-189	352	24	angiogenesis	angiogenesis	NOUN
admet-189	352	25	with	with	ADP
admet-189	352	26	high	high	ADJ
admet-189	352	27	affinity	affinity	NOUN
admet-189	352	28	for	for	ADP
admet-189	352	29	receptors	receptor	NOUN
admet-189	352	30	[	[	X
admet-189	352	31	86	86	NUM
admet-189	352	32	]	]	PUNCT
admet-189	352	33	.	.	PUNCT
admet-189	353	1	these	these	DET
admet-189	353	2	finding	finding	NOUN
admet-189	353	3	demonstrated	demonstrate	VERB
admet-189	353	4	that	that	SCONJ
admet-189	353	5	polymeric	polymeric	ADJ
admet-189	353	6	nanoparticulate	nanoparticulate	ADJ
admet-189	353	7	hydrogels	hydrogel	NOUN
admet-189	353	8	can	can	AUX
admet-189	353	9	act	act	VERB
admet-189	353	10	as	as	ADP
admet-189	353	11	effective	effective	ADJ
admet-189	353	12	carriers	carrier	NOUN
admet-189	353	13	for	for	ADP
admet-189	353	14	local	local	ADJ
admet-189	353	15	delivery	delivery	NOUN
admet-189	353	16	of	of	ADP
admet-189	353	17	drugs	drug	NOUN
admet-189	353	18	in	in	ADP
admet-189	353	19	pd	pd	PROPN
admet-189	353	20	.	.	PUNCT
admet-189	354	1	nevertheless	nevertheless	ADV
admet-189	354	2	,	,	PUNCT
admet-189	354	3	these	these	DET
admet-189	354	4	techniques	technique	NOUN
admet-189	354	5	are	be	AUX
admet-189	354	6	limited	limit	VERB
admet-189	354	7	due	due	ADP
admet-189	354	8	to	to	ADP
admet-189	354	9	their	their	PRON
admet-189	354	10	invasive	invasive	ADJ
admet-189	354	11	nature	nature	NOUN
admet-189	355	1	[	[	X
admet-189	355	2	77,87	77,87	X
admet-189	355	3	]	]	PUNCT
admet-189	355	4	.	.	PUNCT
admet-189	356	1	recently	recently	ADV
admet-189	356	2	,	,	PUNCT
admet-189	356	3	intranasal	intranasal	ADJ
admet-189	356	4	routes	route	NOUN
admet-189	356	5	through	through	ADP
admet-189	356	6	olfactory	olfactory	NOUN
admet-189	356	7	or	or	CCONJ
admet-189	356	8	trigeminal	trigeminal	ADJ
admet-189	356	9	pathways	pathway	NOUN
admet-189	356	10	have	have	AUX
admet-189	356	11	been	be	AUX
admet-189	356	12	explored	explore	VERB
admet-189	356	13	for	for	ADP
admet-189	356	14	transporting	transport	VERB
admet-189	356	15	actives	active	NOUN
admet-189	356	16	to	to	ADP
admet-189	356	17	the	the	DET
admet-189	356	18	brain	brain	NOUN
admet-189	356	19	.	.	PUNCT
admet-189	357	1	intranasal	intranasal	PROPN
admet-189	357	2	administration	administration	NOUN
admet-189	357	3	has	have	VERB
admet-189	357	4	the	the	DET
admet-189	357	5	potential	potential	NOUN
admet-189	357	6	to	to	PART
admet-189	357	7	circumvent	circumvent	VERB
admet-189	357	8	the	the	DET
admet-189	357	9	bbb	bbb	NOUN
admet-189	357	10	via	via	ADP
admet-189	357	11	intracellular	intracellular	ADJ
admet-189	357	12	or	or	CCONJ
admet-189	357	13	extracellular	extracellular	ADJ
admet-189	357	14	pathways	pathway	NOUN
admet-189	357	15	.	.	PUNCT
admet-189	358	1	the	the	DET
admet-189	358	2	intracellular	intracellular	ADJ
admet-189	358	3	pathways	pathway	NOUN
admet-189	358	4	include	include	VERB
admet-189	358	5	endocytosis	endocytosis	NOUN
admet-189	358	6	(	(	PUNCT
admet-189	358	7	adsorptive	adsorptive	ADJ
admet-189	358	8	or	or	CCONJ
admet-189	358	9	receptor	receptor	NOUN
admet-189	358	10	mediated	mediate	VERB
admet-189	358	11	)	)	PUNCT
admet-189	358	12	into	into	ADP
admet-189	358	13	olfactory	olfactory	ADJ
admet-189	358	14	sensory	sensory	ADJ
admet-189	358	15	neurons	neuron	NOUN
admet-189	358	16	followed	follow	VERB
admet-189	358	17	by	by	ADP
admet-189	358	18	intraneuronal	intraneuronal	ADJ
admet-189	358	19	transport	transport	NOUN
admet-189	358	20	(	(	PUNCT
admet-189	358	21	transcytosis	transcytosis	NOUN
admet-189	358	22	)	)	PUNCT
admet-189	358	23	into	into	ADP
admet-189	358	24	trigeminal	trigeminal	ADJ
admet-189	358	25	nerves	nerve	NOUN
admet-189	358	26	whereas	whereas	SCONJ
admet-189	358	27	,	,	PUNCT
admet-189	358	28	extracellular	extracellular	ADJ
admet-189	358	29	pathways	pathway	NOUN
admet-189	358	30	include	include	VERB
admet-189	358	31	paracellular	paracellular	ADJ
admet-189	358	32	diffusion	diffusion	NOUN
admet-189	358	33	to	to	ADP
admet-189	358	34	the	the	DET
admet-189	358	35	lamina	lamina	ADJ
admet-189	358	36	propria	propria	PROPN
admet-189	358	37	through	through	ADP
admet-189	358	38	perineural	perineural	ADJ
admet-189	358	39	or	or	CCONJ
admet-189	358	40	perivascular	perivascular	ADJ
admet-189	358	41	channels	channel	NOUN
admet-189	358	42	[	[	X
admet-189	358	43	88,89	88,89	NOUN
admet-189	358	44	]	]	PUNCT
admet-189	358	45	.	.	PUNCT
admet-189	359	1	intranasal	intranasal	ADJ
admet-189	359	2	administrations	administration	NOUN
admet-189	359	3	offer	offer	VERB
admet-189	359	4	benefits	benefit	NOUN
admet-189	359	5	like	like	ADP
admet-189	359	6	rapid	rapid	ADJ
admet-189	359	7	onset	onset	NOUN
admet-189	359	8	of	of	ADP
admet-189	359	9	action	action	NOUN
admet-189	359	10	and	and	CCONJ
admet-189	359	11	reduced	reduce	VERB
admet-189	359	12	systemic	systemic	ADJ
admet-189	359	13	toxicities	toxicity	NOUN
admet-189	359	14	for	for	ADP
admet-189	359	15	delivering	deliver	VERB
admet-189	359	16	the	the	DET
admet-189	359	17	therapeutics	therapeutic	NOUN
admet-189	359	18	to	to	ADP
admet-189	359	19	the	the	DET
admet-189	359	20	brain	brain	NOUN
admet-189	359	21	.	.	PUNCT
admet-189	360	1	however	however	ADV
admet-189	360	2	,	,	PUNCT
admet-189	360	3	mucocilliary	mucocilliary	ADJ
admet-189	360	4	clearance	clearance	NOUN
admet-189	360	5	limits	limit	VERB
admet-189	360	6	the	the	DET
admet-189	360	7	residence	residence	NOUN
admet-189	360	8	time	time	NOUN
admet-189	360	9	when	when	SCONJ
admet-189	360	10	drug	drug	NOUN
admet-189	360	11	solutions	solution	NOUN
admet-189	360	12	are	be	AUX
admet-189	360	13	delivered	deliver	VERB
admet-189	360	14	intranasally	intranasally	ADV
admet-189	360	15	.	.	PUNCT
admet-189	361	1	[	[	X
admet-189	361	2	90	90	NUM
admet-189	361	3	]	]	PUNCT
admet-189	361	4	.	.	PUNCT
admet-189	362	1	recently	recently	ADV
admet-189	362	2	,	,	PUNCT
admet-189	362	3	wen	wen	PROPN
admet-189	362	4	et	et	PROPN
admet-189	362	5	al	al	PROPN
admet-189	362	6	.	.	PROPN
admet-189	362	7	(	(	PUNCT
admet-189	362	8	2011	2011	NUM
admet-189	362	9	)	)	PUNCT
admet-189	362	10	demonstrated	demonstrate	VERB
admet-189	362	11	that	that	SCONJ
admet-189	362	12	intranasal	intranasal	ADJ
admet-189	362	13	administration	administration	NOUN
admet-189	362	14	showed	show	VERB
admet-189	362	15	improved	improve	VERB
admet-189	362	16	therapeutic	therapeutic	ADJ
admet-189	362	17	efficacy	efficacy	NOUN
admet-189	362	18	of	of	ADP
admet-189	362	19	urocortin	urocortin	PROPN
admet-189	362	20	(	(	PUNCT
admet-189	362	21	corticotrophin	corticotrophin	NOUN
admet-189	362	22	releasing	releasing	NOUN
admet-189	362	23	factor	factor	NOUN
admet-189	362	24	related	relate	VERB
admet-189	362	25	peptide	peptide	NOUN
admet-189	362	26	)	)	PUNCT
admet-189	362	27	when	when	SCONJ
admet-189	362	28	encapsulated	encapsulate	VERB
admet-189	362	29	in	in	ADP
admet-189	362	30	odorranalectin	odorranalectin	NOUN
admet-189	362	31	(	(	PUNCT
admet-189	362	32	bioadhesive	bioadhesive	ADJ
admet-189	362	33	from	from	ADP
admet-189	362	34	lectin	lectin	PROPN
admet-189	362	35	family	family	NOUN
admet-189	362	36	)	)	PUNCT
admet-189	362	37	functionalized	functionalize	VERB
admet-189	362	38	peg	peg	NOUN
admet-189	362	39	-	-	PUNCT
admet-189	362	40	plga	plga	NOUN
admet-189	362	41	nanoparticles	nanoparticle	NOUN
admet-189	362	42	in	in	ADP
admet-189	362	43	hemiparkinsonian	hemiparkinsonian	ADJ
admet-189	362	44	rats	rat	NOUN
admet-189	362	45	[	[	X
admet-189	362	46	91	91	NUM
admet-189	362	47	]	]	PUNCT
admet-189	362	48	.	.	PUNCT
admet-189	363	1	when	when	SCONJ
admet-189	363	2	administered	administer	VERB
admet-189	363	3	intranasally	intranasally	ADV
admet-189	363	4	,	,	PUNCT
admet-189	363	5	the	the	DET
admet-189	363	6	odorranalectin	odorranalectin	NOUN
admet-189	363	7	functionalized	functionalize	VERB
admet-189	363	8	nanoparticles	nanoparticle	NOUN
admet-189	363	9	showed	show	VERB
admet-189	363	10	higher	high	ADJ
admet-189	363	11	brain	brain	NOUN
admet-189	363	12	uptake	uptake	ADJ
admet-189	363	13	and	and	CCONJ
admet-189	363	14	enhanced	enhance	VERB
admet-189	363	15	neuroprotection	neuroprotection	NOUN
admet-189	363	16	in	in	ADP
admet-189	363	17	experimental	experimental	ADJ
admet-189	363	18	animals	animal	NOUN
admet-189	363	19	through	through	ADP
admet-189	363	20	direct	direct	ADJ
admet-189	363	21	pathway	pathway	NOUN
admet-189	363	22	.	.	PUNCT
admet-189	364	1	similarly	similarly	ADV
admet-189	364	2	,	,	PUNCT
admet-189	364	3	migliore	migliore	PROPN
admet-189	364	4	et	et	PROPN
admet-189	364	5	al	al	PROPN
admet-189	364	6	.	.	PROPN
admet-189	364	7	(	(	PUNCT
admet-189	364	8	2014	2014	NUM
admet-189	364	9	)	)	PUNCT
admet-189	364	10	reported	report	VERB
admet-189	364	11	the	the	DET
admet-189	364	12	neurotropic	neurotropic	NOUN
admet-189	364	13	and	and	CCONJ
admet-189	364	14	neuroprotective	neuroprotective	ADJ
admet-189	364	15	effect	effect	NOUN
admet-189	364	16	of	of	ADP
admet-189	364	17	gdnf	gdnf	ADJ
admet-189	364	18	following	follow	VERB
admet-189	364	19	intranasal	intranasal	ADJ
admet-189	364	20	administration	administration	NOUN
admet-189	364	21	of	of	ADP
admet-189	364	22	gdnf	gdnf	PROPN
admet-189	364	23	loaded	load	VERB
admet-189	364	24	cationic	cationic	ADJ
admet-189	364	25	liposomes	liposome	NOUN
admet-189	364	26	(	(	PUNCT
admet-189	364	27	made	make	VERB
admet-189	364	28	up	up	ADP
admet-189	364	29	of	of	ADP
admet-189	364	30	dioleoylphosphatidylcholine	dioleoylphosphatidylcholine	NOUN
admet-189	364	31	(	(	PUNCT
admet-189	364	32	dopc	dopc	NOUN
admet-189	364	33	)	)	PUNCT
admet-189	364	34	,	,	PUNCT
admet-189	364	35	cholesterol	cholesterol	NOUN
admet-189	364	36	,	,	PUNCT
admet-189	364	37	and	and	CCONJ
admet-189	364	38	stearylamine	stearylamine	NOUN
admet-189	364	39	)	)	PUNCT
admet-189	365	1	[	[	X
admet-189	365	2	92	92	NUM
admet-189	365	3	]	]	SYM
admet-189	365	4	.	.	PUNCT
admet-189	366	1	intranasal	intranasal	PROPN
admet-189	366	2	gdnf	gdnf	PROPN
admet-189	366	3	protected	protect	VERB
admet-189	366	4	the	the	DET
admet-189	366	5	dopamine	dopamine	NOUN
admet-189	366	6	neurons	neuron	NOUN
admet-189	366	7	within	within	ADP
admet-189	366	8	substantia	substantia	NOUN
admet-189	366	9	nigra	nigra	NOUN
admet-189	366	10	from	from	ADP
admet-189	366	11	acute	acute	ADJ
admet-189	366	12	6	6	NUM
admet-189	366	13	-	-	PUNCT
admet-189	366	14	ohdp	ohdp	NOUN
admet-189	366	15	induced	induced	ADJ
admet-189	366	16	neuronal	neuronal	ADJ
admet-189	366	17	toxic	toxic	ADJ
admet-189	366	18	insult	insult	NOUN
admet-189	366	19	[	[	X
admet-189	366	20	92	92	NUM
admet-189	366	21	]	]	PUNCT
admet-189	366	22	.	.	PUNCT
admet-189	367	1	sharma	sharma	PROPN
admet-189	367	2	et	et	PROPN
admet-189	367	3	al	al	PROPN
admet-189	367	4	.	.	PROPN
admet-189	368	1	(	(	PUNCT
admet-189	368	2	2013	2013	NUM
admet-189	368	3	)	)	PUNCT
admet-189	368	4	reported	report	VERB
admet-189	368	5	intranasal	intranasal	ADJ
admet-189	368	6	delivery	delivery	NOUN
admet-189	368	7	of	of	ADP
admet-189	368	8	pluronic	pluronic	ADJ
admet-189	368	9	f-127	f-127	NOUN
admet-189	368	10	based	base	VERB
admet-189	368	11	thermoreversible	thermoreversible	ADJ
admet-189	368	12	gel	gel	NOUN
admet-189	368	13	containing	contain	VERB
admet-189	368	14	levodopa	levodopa	NOUN
admet-189	368	15	encapsulated	encapsulate	VERB
admet-189	368	16	chitosan	chitosan	NOUN
admet-189	368	17	nanoparticles	nanoparticle	NOUN
admet-189	368	18	[	[	X
admet-189	368	19	93	93	NUM
admet-189	368	20	]	]	PUNCT
admet-189	368	21	.	.	PUNCT
admet-189	369	1	chitosan	chitosan	PROPN
admet-189	369	2	being	be	AUX
admet-189	369	3	a	a	DET
admet-189	369	4	muchoadhesive	muchoadhesive	ADJ
admet-189	369	5	polymer	polymer	NOUN
admet-189	369	6	plays	play	VERB
admet-189	369	7	an	an	DET
admet-189	369	8	important	important	ADJ
admet-189	369	9	role	role	NOUN
admet-189	369	10	in	in	ADP
admet-189	369	11	improving	improve	VERB
admet-189	369	12	drug	drug	NOUN
admet-189	369	13	absorption	absorption	NOUN
admet-189	369	14	through	through	ADP
admet-189	369	15	nasal	nasal	ADJ
admet-189	369	16	mucosa	mucosa	NOUN
admet-189	369	17	and	and	CCONJ
admet-189	369	18	can	can	AUX
admet-189	369	19	lead	lead	VERB
admet-189	369	20	to	to	ADP
admet-189	369	21	opening	opening	NOUN
admet-189	369	22	of	of	ADP
admet-189	369	23	tight	tight	ADJ
admet-189	369	24	junctions	junction	NOUN
admet-189	369	25	across	across	ADP
admet-189	369	26	bbb	bbb	PROPN
admet-189	369	27	.	.	PUNCT
admet-189	370	1	the	the	DET
admet-189	370	2	in	in	ADP
admet-189	370	3	vivo	vivo	ADJ
admet-189	370	4	findings	finding	NOUN
admet-189	370	5	revealed	reveal	VERB
admet-189	370	6	that	that	SCONJ
admet-189	370	7	intranasal	intranasal	ADJ
admet-189	370	8	administration	administration	NOUN
admet-189	370	9	showed	show	VERB
admet-189	370	10	maximum	maximum	ADJ
admet-189	370	11	recovery	recovery	NOUN
admet-189	370	12	of	of	ADP
admet-189	370	13	levodopa	levodopa	NOUN
admet-189	370	14	within	within	ADP
admet-189	370	15	the	the	DET
admet-189	370	16	brain	brain	NOUN
admet-189	370	17	with	with	ADP
admet-189	370	18	chitosan	chitosan	ADJ
admet-189	370	19	nanoparticles	nanoparticle	NOUN
admet-189	370	20	[	[	X
admet-189	370	21	93	93	NUM
admet-189	370	22	]	]	PUNCT
admet-189	370	23	.	.	PUNCT
admet-189	371	1	md	md	PROPN
admet-189	371	2	and	and	CCONJ
admet-189	371	3	colleagues	colleague	NOUN
admet-189	371	4	(	(	PUNCT
admet-189	371	5	2013	2013	NUM
admet-189	371	6	)	)	PUNCT
admet-189	371	7	have	have	VERB
admet-189	371	8	studies	study	NOUN
admet-189	371	9	the	the	DET
admet-189	371	10	potential	potential	NOUN
admet-189	371	11	of	of	ADP
admet-189	371	12	intranasal	intranasal	ADJ
admet-189	371	13	route	route	NOUN
admet-189	371	14	to	to	PART
admet-189	371	15	enhance	enhance	VERB
admet-189	371	16	the	the	DET
admet-189	371	17	brain	brain	NOUN
admet-189	371	18	delivery	delivery	NOUN
admet-189	371	19	of	of	ADP
admet-189	371	20	bromocriptine	bromocriptine	NOUN
admet-189	371	21	(	(	PUNCT
admet-189	371	22	brc	brc	NOUN
admet-189	371	23	)	)	PUNCT
admet-189	371	24	loaded	load	VERB
admet-189	371	25	chitosan	chitosan	NOUN
admet-189	371	26	nanoparticles	nanoparticle	NOUN
admet-189	371	27	in	in	ADP
admet-189	371	28	haloperidol	haloperidol	PROPN
admet-189	371	29	induced	induce	VERB
admet-189	371	30	pd	pd	NOUN
admet-189	371	31	mice	mouse	NOUN
admet-189	371	32	[	[	X
admet-189	371	33	94	94	NUM
admet-189	371	34	]	]	PUNCT
admet-189	371	35	.	.	PUNCT
admet-189	372	1	when	when	SCONJ
admet-189	372	2	administered	administer	VERB
admet-189	372	3	intranasally	intranasally	ADV
admet-189	372	4	the	the	DET
admet-189	372	5	brc	brc	NOUN
admet-189	372	6	loaded	load	VERB
admet-189	372	7	nanoparticles	nanoparticle	NOUN
admet-189	372	8	showed	show	VERB
admet-189	372	9	pronounced	pronounce	VERB
admet-189	372	10	reversion	reversion	NOUN
admet-189	372	11	of	of	ADP
admet-189	372	12	catalepsy	catalepsy	PROPN
admet-189	372	13	and	and	CCONJ
admet-189	372	14	akinesia	akinesia	NOUN
admet-189	372	15	induced	induce	VERB
admet-189	372	16	by	by	ADP
admet-189	372	17	haloperidol	haloperidol	NOUN
admet-189	372	18	.	.	PUNCT
admet-189	373	1	the	the	DET
admet-189	373	2	biodistribution	biodistribution	NOUN
admet-189	373	3	study	study	NOUN
admet-189	373	4	revealed	reveal	VERB
admet-189	373	5	higher	high	ADJ
admet-189	373	6	brain	brain	NOUN
admet-189	373	7	/	/	SYM
admet-189	373	8	blood	blood	NOUN
admet-189	373	9	ratio	ratio	NOUN
admet-189	373	10	of	of	ADP
admet-189	373	11	brc	brc	NOUN
admet-189	373	12	loaded	load	VERB
admet-189	373	13	nanoparticles	nanoparticle	NOUN
admet-189	373	14	following	follow	VERB
admet-189	373	15	intranasal	intranasal	ADJ
admet-189	373	16	administration	administration	NOUN
admet-189	373	17	than	than	ADP
admet-189	373	18	that	that	PRON
admet-189	373	19	of	of	ADP
admet-189	373	20	intravenous	intravenous	ADJ
admet-189	373	21	route	route	NOUN
admet-189	373	22	at	at	ADP
admet-189	373	23	0.5	0.5	NUM
admet-189	373	24	hours	hour	NOUN
admet-189	373	25	,	,	PUNCT
admet-189	373	26	indicating	indicate	VERB
admet-189	373	27	direct	direct	ADJ
admet-189	373	28	nose	nose	NOUN
admet-189	373	29	to	to	ADP
admet-189	373	30	brain	brain	NOUN
admet-189	373	31	transport	transport	NOUN
admet-189	373	32	of	of	ADP
admet-189	373	33	brc	brc	NOUN
admet-189	373	34	circumventing	circumvent	VERB
admet-189	373	35	the	the	DET
admet-189	373	36	bbb	bbb	PROPN
admet-189	373	37	.	.	PUNCT
admet-189	374	1	the	the	DET
admet-189	374	2	gamma	gamma	PROPN
admet-189	374	3	scintigraphy	scintigraphy	PROPN
admet-189	374	4	r.	r.	PROPN
admet-189	374	5	banerjee	banerjee	PROPN
admet-189	374	6	et	et	PROPN
admet-189	374	7	al	al	PROPN
admet-189	374	8	.	.	PROPN
admet-189	374	9	admet	admet	PROPN
admet-189	374	10	&	&	CCONJ
admet-189	374	11	dmpk	dmpk	PROPN
admet-189	374	12	3(3	3(3	NUM
admet-189	374	13	)	)	PUNCT
admet-189	374	14	(	(	PUNCT
admet-189	374	15	2015	2015	NUM
admet-189	374	16	)	)	PUNCT
admet-189	374	17	155	155	NUM
admet-189	374	18	-	-	SYM
admet-189	374	19	181	181	NUM
admet-189	374	20	168	168	NUM
admet-189	374	21	study	study	NOUN
admet-189	374	22	revealed	reveal	VERB
admet-189	374	23	higher	high	ADJ
admet-189	374	24	brain	brain	NOUN
admet-189	374	25	uptake	uptake	ADJ
admet-189	374	26	and	and	CCONJ
admet-189	374	27	enhanced	enhance	VERB
admet-189	374	28	antioxidant	antioxidant	ADJ
admet-189	374	29	potential	potential	NOUN
admet-189	374	30	of	of	ADP
admet-189	374	31	brc	brc	NOUN
admet-189	374	32	following	follow	VERB
admet-189	374	33	intranasal	intranasal	ADJ
admet-189	374	34	administration	administration	NOUN
admet-189	374	35	[	[	X
admet-189	374	36	94	94	NUM
admet-189	374	37	]	]	PUNCT
admet-189	374	38	.	.	PUNCT
admet-189	375	1	a	a	DET
admet-189	375	2	flowchart	flowchart	NOUN
admet-189	375	3	of	of	ADP
admet-189	375	4	the	the	DET
admet-189	375	5	various	various	ADJ
admet-189	375	6	routes	route	NOUN
admet-189	375	7	and	and	CCONJ
admet-189	375	8	approaches	approach	NOUN
admet-189	375	9	to	to	PART
admet-189	375	10	cross	cross	VERB
admet-189	375	11	the	the	DET
admet-189	375	12	bbb	bbb	PROPN
admet-189	375	13	has	have	AUX
admet-189	375	14	been	be	AUX
admet-189	375	15	outlined	outline	VERB
admet-189	375	16	in	in	ADP
admet-189	375	17	figure	figure	NOUN
admet-189	375	18	4	4	NUM
admet-189	375	19	.	.	PUNCT
admet-189	375	20	figure	figure	VERB
admet-189	375	21	4	4	NUM
admet-189	375	22	.	.	PUNCT
admet-189	375	23	novel	novel	ADJ
admet-189	375	24	approaches	approach	NOUN
admet-189	375	25	for	for	ADP
admet-189	375	26	drug	drug	NOUN
admet-189	375	27	delivery	delivery	NOUN
admet-189	375	28	across	across	ADP
admet-189	375	29	the	the	DET
admet-189	375	30	bbb	bbb	NOUN
admet-189	375	31	(	(	PUNCT
admet-189	375	32	the	the	DET
admet-189	375	33	approaches	approach	NOUN
admet-189	375	34	are	be	AUX
admet-189	375	35	mentioned	mention	VERB
admet-189	375	36	within	within	ADP
admet-189	375	37	boxes	box	NOUN
admet-189	375	38	.	.	PUNCT
admet-189	376	1	those	those	PRON
admet-189	376	2	in	in	ADP
admet-189	376	3	red	red	ADJ
admet-189	376	4	are	be	AUX
admet-189	376	5	invasive	invasive	ADJ
admet-189	376	6	approaches	approach	NOUN
admet-189	376	7	and	and	CCONJ
admet-189	376	8	those	those	PRON
admet-189	376	9	in	in	ADP
admet-189	376	10	black	black	ADJ
admet-189	376	11	are	be	AUX
admet-189	376	12	relatively	relatively	ADV
admet-189	376	13	less	less	ADV
admet-189	376	14	invasive	invasive	ADJ
admet-189	376	15	approaches	approach	NOUN
admet-189	376	16	for	for	ADP
admet-189	376	17	drug	drug	NOUN
admet-189	376	18	delivery	delivery	NOUN
admet-189	376	19	.	.	PUNCT
admet-189	376	20	)	)	PUNCT
admet-189	377	1	passive	passive	ADJ
admet-189	377	2	targeting	target	VERB
admet-189	377	3	(	(	PUNCT
admet-189	377	4	macrophage	macrophage	ADJ
admet-189	377	5	loaded	load	VERB
admet-189	377	6	)	)	PUNCT
admet-189	377	7	nanotechnology	nanotechnology	NOUN
admet-189	377	8	platforms	platform	NOUN
admet-189	377	9	possess	possess	VERB
admet-189	377	10	the	the	DET
admet-189	377	11	ability	ability	NOUN
admet-189	377	12	to	to	PART
admet-189	377	13	accumulate	accumulate	VERB
admet-189	377	14	in	in	ADP
admet-189	377	15	a	a	DET
admet-189	377	16	specific	specific	ADJ
admet-189	377	17	organ	organ	NOUN
admet-189	377	18	without	without	ADP
admet-189	377	19	active	active	ADJ
admet-189	377	20	targeting	targeting	NOUN
admet-189	377	21	moieties	moiety	NOUN
admet-189	377	22	on	on	ADP
admet-189	377	23	its	its	PRON
admet-189	377	24	surface	surface	NOUN
admet-189	377	25	due	due	ADP
admet-189	377	26	to	to	ADP
admet-189	377	27	certain	certain	ADJ
admet-189	377	28	inherent	inherent	ADJ
admet-189	377	29	characteristics	characteristic	NOUN
admet-189	377	30	.	.	PUNCT
admet-189	378	1	for	for	ADP
admet-189	378	2	example	example	NOUN
admet-189	378	3	,	,	PUNCT
admet-189	378	4	in	in	ADP
admet-189	378	5	cancers	cancer	NOUN
admet-189	378	6	,	,	PUNCT
admet-189	378	7	small	small	ADJ
admet-189	378	8	size	size	NOUN
admet-189	378	9	of	of	ADP
admet-189	378	10	nanoparticles	nanoparticle	NOUN
admet-189	378	11	allow	allow	VERB
admet-189	378	12	them	they	PRON
admet-189	378	13	to	to	PART
admet-189	378	14	preferentially	preferentially	ADV
admet-189	378	15	accumulate	accumulate	VERB
admet-189	378	16	at	at	ADP
admet-189	378	17	tumor	tumor	NOUN
admet-189	378	18	sites	site	NOUN
admet-189	378	19	by	by	ADP
admet-189	378	20	the	the	DET
admet-189	378	21	enhanced	enhance	VERB
admet-189	378	22	permeation	permeation	NOUN
admet-189	378	23	and	and	CCONJ
admet-189	378	24	retention	retention	NOUN
admet-189	378	25	effect	effect	NOUN
admet-189	378	26	(	(	PUNCT
admet-189	378	27	epr	epr	ADJ
admet-189	378	28	effect	effect	NOUN
admet-189	378	29	)	)	PUNCT
admet-189	378	30	which	which	PRON
admet-189	378	31	leverages	leverage	VERB
admet-189	378	32	the	the	DET
admet-189	378	33	leakiness	leakiness	NOUN
admet-189	378	34	of	of	ADP
admet-189	378	35	blood	blood	NOUN
admet-189	378	36	vessels	vessel	NOUN
admet-189	378	37	in	in	ADP
admet-189	378	38	a	a	DET
admet-189	378	39	tumor	tumor	NOUN
admet-189	378	40	and	and	CCONJ
admet-189	378	41	absence	absence	NOUN
admet-189	378	42	of	of	ADP
admet-189	378	43	lymphatics	lymphatic	NOUN
admet-189	378	44	to	to	PART
admet-189	378	45	deliver	deliver	VERB
admet-189	378	46	the	the	DET
admet-189	378	47	nanoparticles	nanoparticle	NOUN
admet-189	378	48	[	[	X
admet-189	378	49	95	95	NUM
admet-189	378	50	]	]	PUNCT
admet-189	378	51	.	.	PUNCT
admet-189	379	1	in	in	ADP
admet-189	379	2	parkinson	parkinson	NOUN
admet-189	379	3	’s	’s	PART
admet-189	379	4	disease	disease	NOUN
admet-189	379	5	,	,	PUNCT
admet-189	379	6	the	the	DET
admet-189	379	7	bbb	bbb	PROPN
admet-189	379	8	is	be	AUX
admet-189	379	9	an	an	DET
admet-189	379	10	important	important	ADJ
admet-189	379	11	barrier	barrier	NOUN
admet-189	379	12	that	that	PRON
admet-189	379	13	needs	need	VERB
admet-189	379	14	to	to	PART
admet-189	379	15	be	be	AUX
admet-189	379	16	crossed	cross	VERB
admet-189	379	17	for	for	ADP
admet-189	379	18	the	the	DET
admet-189	379	19	delivery	delivery	NOUN
admet-189	379	20	of	of	ADP
admet-189	379	21	therapeutics	therapeutic	NOUN
admet-189	379	22	.	.	PUNCT
admet-189	380	1	this	this	PRON
admet-189	380	2	can	can	AUX
admet-189	380	3	be	be	AUX
admet-189	380	4	achieved	achieve	VERB
admet-189	380	5	passively	passively	ADV
admet-189	380	6	through	through	ADP
admet-189	380	7	macrophages	macrophage	NOUN
admet-189	380	8	.	.	PUNCT
admet-189	381	1	in	in	ADP
admet-189	381	2	pd	pd	PROPN
admet-189	381	3	there	there	PRON
admet-189	381	4	is	be	VERB
admet-189	381	5	a	a	DET
admet-189	381	6	chemokine	chemokine	ADJ
admet-189	381	7	-	-	PUNCT
admet-189	381	8	gradient	gradient	NOUN
admet-189	381	9	that	that	PRON
admet-189	381	10	gets	get	AUX
admet-189	381	11	induced	induce	VERB
admet-189	381	12	through	through	ADP
admet-189	381	13	neuroinflammatory	neuroinflammatory	ADJ
admet-189	381	14	responses	response	NOUN
admet-189	381	15	which	which	PRON
admet-189	381	16	allow	allow	VERB
admet-189	381	17	concentration	concentration	NOUN
admet-189	381	18	of	of	ADP
admet-189	381	19	macrophages	macrophage	NOUN
admet-189	381	20	in	in	ADP
admet-189	381	21	the	the	DET
admet-189	381	22	brain	brain	NOUN
admet-189	381	23	as	as	SCONJ
admet-189	381	24	outlined	outline	VERB
admet-189	381	25	in	in	ADP
admet-189	381	26	figure	figure	NOUN
admet-189	381	27	5	5	NUM
admet-189	381	28	.	.	PUNCT
admet-189	382	1	hence	hence	ADV
admet-189	382	2	,	,	PUNCT
admet-189	382	3	it	it	PRON
admet-189	382	4	is	be	AUX
admet-189	382	5	possible	possible	ADJ
admet-189	382	6	to	to	PART
admet-189	382	7	use	use	VERB
admet-189	382	8	macrophages	macrophage	NOUN
admet-189	382	9	as	as	ADP
admet-189	382	10	drug	drug	NOUN
admet-189	382	11	carriers	carrier	NOUN
admet-189	382	12	for	for	ADP
admet-189	382	13	the	the	DET
admet-189	382	14	delivery	delivery	NOUN
admet-189	382	15	of	of	ADP
admet-189	382	16	various	various	ADJ
admet-189	382	17	therapeutic	therapeutic	ADJ
admet-189	382	18	payloads	payload	NOUN
admet-189	382	19	[	[	X
admet-189	382	20	96	96	NUM
admet-189	382	21	]	]	PUNCT
admet-189	382	22	.	.	PUNCT
admet-189	383	1	batrakova	batrakova	AUX
admet-189	383	2	et	et	PROPN
admet-189	383	3	al	al	PROPN
admet-189	383	4	.	.	PROPN
admet-189	383	5	delivered	deliver	VERB
admet-189	383	6	catalase	catalase	NOUN
admet-189	383	7	using	use	VERB
admet-189	383	8	bone	bone	NOUN
admet-189	383	9	-	-	PUNCT
admet-189	383	10	marrow	marrow	NOUN
admet-189	383	11	-	-	PUNCT
admet-189	383	12	derived	derive	VERB
admet-189	383	13	macrophage	macrophage	NOUN
admet-189	383	14	(	(	PUNCT
admet-189	383	15	bmm	bmm	PROPN
admet-189	383	16	)	)	PUNCT
admet-189	383	17	systems	system	NOUN
admet-189	383	18	to	to	ADP
admet-189	383	19	pd	pd	ADJ
admet-189	383	20	-	-	PUNCT
admet-189	383	21	affected	affect	VERB
admet-189	383	22	brain	brain	NOUN
admet-189	383	23	regions	region	NOUN
admet-189	383	24	in	in	ADP
admet-189	383	25	an	an	DET
admet-189	383	26	animal	animal	NOUN
admet-189	383	27	model	model	NOUN
admet-189	383	28	[	[	X
admet-189	383	29	97	97	NUM
admet-189	383	30	]	]	PUNCT
admet-189	383	31	.	.	PUNCT
admet-189	384	1	the	the	DET
admet-189	384	2	self	self	NOUN
admet-189	384	3	-	-	PUNCT
admet-189	384	4	assembled	assemble	VERB
admet-189	384	5	catalase	catalase	NOUN
admet-189	384	6	/	/	SYM
admet-189	384	7	polymer	polymer	NOUN
admet-189	384	8	complexes	complex	NOUN
admet-189	384	9	referred	refer	VERB
admet-189	384	10	to	to	ADP
admet-189	384	11	as	as	ADP
admet-189	384	12	nanozymes	nanozyme	NOUN
admet-189	384	13	that	that	PRON
admet-189	384	14	were	be	AUX
admet-189	384	15	60	60	NUM
admet-189	384	16	-	-	SYM
admet-189	384	17	100	100	NUM
admet-189	384	18	nm	nm	NOUN
admet-189	384	19	in	in	ADP
admet-189	384	20	size	size	NOUN
admet-189	384	21	were	be	AUX
admet-189	384	22	taken	take	VERB
admet-189	384	23	up	up	ADP
admet-189	384	24	by	by	ADP
admet-189	384	25	the	the	DET
admet-189	384	26	bmms	bmms	NOUN
admet-189	384	27	and	and	CCONJ
admet-189	384	28	showed	show	VERB
admet-189	384	29	sustained	sustained	ADJ
admet-189	384	30	release	release	NOUN
admet-189	384	31	for	for	ADP
admet-189	384	32	about	about	ADV
admet-189	384	33	24	24	NUM
admet-189	384	34	hours	hour	NOUN
admet-189	384	35	as	as	SCONJ
admet-189	384	36	compared	compare	VERB
admet-189	384	37	to	to	ADP
admet-189	384	38	immediate	immediate	ADJ
admet-189	384	39	degradation	degradation	NOUN
admet-189	384	40	of	of	ADP
admet-189	384	41	the	the	DET
admet-189	384	42	free	free	ADJ
admet-189	384	43	enzyme	enzyme	NOUN
admet-189	384	44	[	[	NOUN
admet-189	384	45	97	97	NUM
admet-189	384	46	]	]	PUNCT
admet-189	384	47	.	.	PUNCT
admet-189	385	1	this	this	PRON
admet-189	385	2	had	have	VERB
admet-189	385	3	implications	implication	NOUN
admet-189	385	4	in	in	ADP
admet-189	385	5	decomposition	decomposition	NOUN
admet-189	385	6	of	of	ADP
admet-189	385	7	microglial	microglial	ADJ
admet-189	385	8	hydrogen	hydrogen	NOUN
admet-189	385	9	peroxide	peroxide	NOUN
admet-189	385	10	that	that	PRON
admet-189	385	11	could	could	AUX
admet-189	385	12	reduce	reduce	VERB
admet-189	385	13	oxidative	oxidative	ADJ
admet-189	385	14	stress	stress	NOUN
admet-189	385	15	in	in	ADP
admet-189	385	16	pd	pd	PROPN
admet-189	385	17	.	.	PUNCT
admet-189	386	1	it	it	PRON
admet-189	386	2	was	be	AUX
admet-189	386	3	found	find	VERB
admet-189	386	4	that	that	SCONJ
admet-189	386	5	the	the	DET
admet-189	386	6	nanozymes	nanozyme	NOUN
admet-189	386	7	loaded	load	VERB
admet-189	386	8	into	into	ADP
admet-189	386	9	bmms	bmms	NOUN
admet-189	386	10	increased	increase	VERB
admet-189	386	11	deposition	deposition	NOUN
admet-189	386	12	of	of	ADP
admet-189	386	13	labeled	label	VERB
admet-189	386	14	enzyme	enzyme	NOUN
admet-189	386	15	in	in	ADP
admet-189	386	16	tissues	tissue	NOUN
admet-189	386	17	in	in	ADP
admet-189	386	18	vivo	vivo	NOUN
admet-189	386	19	in	in	ADP
admet-189	386	20	mptp	mptp	PROPN
admet-189	386	21	-	-	PUNCT
admet-189	386	22	treated	treat	VERB
admet-189	386	23	mice	mouse	NOUN
admet-189	386	24	as	as	SCONJ
admet-189	386	25	compared	compare	VERB
admet-189	386	26	to	to	ADP
admet-189	386	27	free	free	ADJ
admet-189	386	28	enzymes	enzyme	NOUN
admet-189	386	29	.	.	PUNCT
admet-189	387	1	the	the	DET
admet-189	387	2	development	development	NOUN
admet-189	387	3	of	of	ADP
admet-189	387	4	such	such	ADJ
admet-189	387	5	nanoparticles	nanoparticle	NOUN
admet-189	387	6	loaded	load	VERB
admet-189	387	7	into	into	ADP
admet-189	387	8	macrophages	macrophage	NOUN
admet-189	387	9	can	can	AUX
admet-189	387	10	help	help	VERB
admet-189	387	11	in	in	ADP
admet-189	387	12	increased	increase	VERB
admet-189	387	13	delivery	delivery	NOUN
admet-189	387	14	admet	admet	NOUN
admet-189	387	15	&	&	CCONJ
admet-189	387	16	dmpk	dmpk	PROPN
admet-189	387	17	3(3	3(3	NUM
admet-189	387	18	)	)	PUNCT
admet-189	387	19	(	(	PUNCT
admet-189	387	20	2015	2015	NUM
admet-189	387	21	)	)	PUNCT
admet-189	387	22	155	155	NUM
admet-189	387	23	-	-	SYM
admet-189	387	24	181	181	NUM
admet-189	387	25	nanotechnology	nanotechnology	NOUN
admet-189	387	26	platforms	platform	NOUN
admet-189	387	27	in	in	ADP
admet-189	387	28	parkinson	parkinson	NOUN
admet-189	387	29	’s	’s	PART
admet-189	387	30	disease	disease	NOUN
admet-189	387	31	doi	doi	NOUN
admet-189	387	32	:	:	PUNCT
admet-189	387	33	10.5599	10.5599	NUM
admet-189	387	34	/	/	SYM
admet-189	387	35	admet.3.3.189	admet.3.3.189	ADP
admet-189	387	36	169	169	NUM
admet-189	387	37	of	of	ADP
admet-189	387	38	therapeutics	therapeutic	NOUN
admet-189	387	39	to	to	ADP
admet-189	387	40	the	the	DET
admet-189	387	41	brain	brain	NOUN
admet-189	387	42	reducing	reduce	VERB
admet-189	387	43	the	the	DET
admet-189	387	44	need	need	NOUN
admet-189	387	45	and	and	CCONJ
admet-189	387	46	the	the	DET
admet-189	387	47	costs	cost	NOUN
admet-189	387	48	associated	associate	VERB
admet-189	387	49	with	with	ADP
admet-189	387	50	active	active	ADJ
admet-189	387	51	targeting	targeting	NOUN
admet-189	387	52	of	of	ADP
admet-189	387	53	nanoparticles	nanoparticle	NOUN
admet-189	387	54	.	.	PUNCT
admet-189	388	1	figure	figure	VERB
admet-189	388	2	5	5	NUM
admet-189	388	3	.	.	PUNCT
admet-189	389	1	use	use	NOUN
admet-189	389	2	of	of	ADP
admet-189	389	3	nanotechnology	nanotechnology	NOUN
admet-189	389	4	for	for	ADP
admet-189	389	5	passive	passive	ADJ
admet-189	389	6	targeting	target	VERB
admet-189	389	7	through	through	ADP
admet-189	389	8	macrophages	macrophage	NOUN
admet-189	389	9	for	for	ADP
admet-189	389	10	drug	drug	NOUN
admet-189	389	11	delivery	delivery	NOUN
admet-189	389	12	in	in	ADP
admet-189	389	13	parkinson	parkinson	NOUN
admet-189	389	14	’s	’s	PART
admet-189	389	15	disease	disease	NOUN
admet-189	389	16	stimulus	stimulus	NOUN
admet-189	389	17	responsive	responsive	ADJ
admet-189	389	18	nanoparticles	nanoparticle	NOUN
admet-189	389	19	nanoscale	nanoscale	ADJ
admet-189	389	20	biomedical	biomedical	ADJ
admet-189	389	21	imaging	imaging	NOUN
admet-189	389	22	for	for	ADP
admet-189	389	23	image	image	NOUN
admet-189	389	24	guided	guide	VERB
admet-189	389	25	therapy	therapy	NOUN
admet-189	389	26	and	and	CCONJ
admet-189	389	27	diagnosis	diagnosis	NOUN
admet-189	389	28	against	against	ADP
admet-189	389	29	neurodegenerative	neurodegenerative	ADJ
admet-189	389	30	diseases	disease	NOUN
admet-189	389	31	is	be	AUX
admet-189	389	32	recently	recently	ADV
admet-189	389	33	emerging	emerge	VERB
admet-189	389	34	.	.	PUNCT
admet-189	390	1	one	one	NUM
admet-189	390	2	of	of	ADP
admet-189	390	3	the	the	DET
admet-189	390	4	widely	widely	ADV
admet-189	390	5	studied	study	VERB
admet-189	390	6	multipurpose	multipurpose	NOUN
admet-189	390	7	systems	system	NOUN
admet-189	390	8	are	be	AUX
admet-189	390	9	magnetic	magnetic	ADJ
admet-189	390	10	nanoparticles	nanoparticle	NOUN
admet-189	390	11	(	(	PUNCT
admet-189	390	12	mnps	mnps	PROPN
admet-189	390	13	)	)	PUNCT
admet-189	390	14	with	with	ADP
admet-189	390	15	mri	mri	NOUN
admet-189	390	16	contrast	contrast	NOUN
admet-189	390	17	for	for	ADP
admet-189	390	18	applications	application	NOUN
admet-189	390	19	like	like	ADP
admet-189	390	20	cellular	cellular	ADJ
admet-189	390	21	and	and	CCONJ
admet-189	390	22	molecular	molecular	ADJ
admet-189	390	23	imaging	imaging	NOUN
admet-189	390	24	of	of	ADP
admet-189	390	25	various	various	ADJ
admet-189	390	26	metastases	metastasis	NOUN
admet-189	390	27	,	,	PUNCT
admet-189	390	28	hyperthermia	hyperthermia	NOUN
admet-189	390	29	,	,	PUNCT
admet-189	390	30	drug	drug	NOUN
admet-189	390	31	delivery	delivery	NOUN
admet-189	390	32	and	and	CCONJ
admet-189	390	33	tissue	tissue	NOUN
admet-189	390	34	repair	repair	NOUN
admet-189	390	35	.	.	PUNCT
admet-189	391	1	in	in	ADP
admet-189	391	2	case	case	NOUN
admet-189	391	3	of	of	ADP
admet-189	391	4	neurodegenerative	neurodegenerative	ADJ
admet-189	391	5	diseases	disease	NOUN
admet-189	391	6	the	the	DET
admet-189	391	7	presence	presence	NOUN
admet-189	391	8	of	of	ADP
admet-189	391	9	structural	structural	ADJ
admet-189	391	10	barrier	barrier	NOUN
admet-189	391	11	likes	like	VERB
admet-189	391	12	bbb	bbb	NOUN
admet-189	391	13	;	;	PUNCT
admet-189	391	14	restrict	restrict	VERB
admet-189	391	15	mnps	mnps	ADJ
admet-189	391	16	access	access	NOUN
admet-189	391	17	to	to	ADP
admet-189	391	18	the	the	DET
admet-189	391	19	cns	cns	NOUN
admet-189	391	20	.	.	PUNCT
admet-189	392	1	therefore	therefore	ADV
admet-189	392	2	smart	smart	ADJ
admet-189	392	3	engineering	engineering	NOUN
admet-189	392	4	of	of	ADP
admet-189	392	5	mnps	mnps	PROPN
admet-189	392	6	with	with	ADP
admet-189	392	7	desired	desire	VERB
admet-189	392	8	size	size	NOUN
admet-189	392	9	and	and	CCONJ
admet-189	392	10	appropriate	appropriate	ADJ
admet-189	392	11	physicochemical	physicochemical	ADJ
admet-189	392	12	properties	property	NOUN
admet-189	392	13	is	be	AUX
admet-189	392	14	important	important	ADJ
admet-189	392	15	to	to	PART
admet-189	392	16	circumvent	circumvent	VERB
admet-189	392	17	the	the	DET
admet-189	392	18	bbb	bbb	PROPN
admet-189	392	19	to	to	PART
admet-189	392	20	gain	gain	VERB
admet-189	392	21	access	access	NOUN
admet-189	392	22	to	to	ADP
admet-189	392	23	the	the	DET
admet-189	392	24	brain	brain	NOUN
admet-189	393	1	[	[	X
admet-189	393	2	70	70	NUM
admet-189	393	3	,	,	PUNCT
admet-189	393	4	98	98	NUM
admet-189	393	5	]	]	PUNCT
admet-189	393	6	.	.	PUNCT
admet-189	394	1	recently	recently	ADV
admet-189	394	2	qiao	qiao	VERB
admet-189	394	3	et	et	PROPN
admet-189	394	4	al	al	PROPN
admet-189	394	5	.	.	PROPN
admet-189	395	1	(	(	PUNCT
admet-189	395	2	2012	2012	NUM
admet-189	395	3	)	)	PUNCT
admet-189	395	4	developed	develop	VERB
admet-189	395	5	target	target	NOUN
admet-189	395	6	specific	specific	ADJ
admet-189	395	7	theranostics	theranostic	NOUN
admet-189	395	8	to	to	PART
admet-189	395	9	facilitate	facilitate	VERB
admet-189	395	10	the	the	DET
admet-189	395	11	access	access	NOUN
admet-189	395	12	of	of	ADP
admet-189	395	13	nanoparticles	nanoparticle	NOUN
admet-189	395	14	across	across	ADP
admet-189	395	15	bbb	bbb	PROPN
admet-189	395	16	through	through	ADP
admet-189	395	17	endocytosis	endocytosis	NOUN
admet-189	395	18	mediated	mediate	VERB
admet-189	395	19	by	by	ADP
admet-189	395	20	lactoferrin	lactoferrin	NOUN
admet-189	395	21	receptor	receptor	NOUN
admet-189	395	22	.	.	PUNCT
admet-189	396	1	pegylated	pegylate	VERB
admet-189	396	2	magnetic	magnetic	ADJ
admet-189	396	3	nanoparticles	nanoparticle	NOUN
admet-189	396	4	(	(	PUNCT
admet-189	396	5	fe3o4	fe3o4	NOUN
admet-189	396	6	)	)	PUNCT
admet-189	396	7	surface	surface	NOUN
admet-189	396	8	modified	modify	VERB
admet-189	396	9	with	with	ADP
admet-189	396	10	lactoferrin	lactoferrin	NOUN
admet-189	396	11	serve	serve	NOUN
admet-189	396	12	as	as	ADP
admet-189	396	13	a	a	DET
admet-189	396	14	brain	brain	NOUN
admet-189	396	15	mri	mri	NOUN
admet-189	396	16	guided	guide	VERB
admet-189	396	17	delivery	delivery	NOUN
admet-189	396	18	probe[99	probe[99	NOUN
admet-189	396	19	]	]	PUNCT
admet-189	396	20	.	.	PUNCT
admet-189	397	1	the	the	DET
admet-189	397	2	in	in	ADV
admet-189	397	3	vitro	vitro	X
admet-189	397	4	porcine	porcine	X
admet-189	397	5	bbb	bbb	PROPN
admet-189	397	6	model	model	NOUN
admet-189	397	7	showed	show	VERB
admet-189	397	8	that	that	SCONJ
admet-189	397	9	amphiphilic	amphiphilic	ADJ
admet-189	397	10	peg	peg	NOUN
admet-189	397	11	coating	coating	NOUN
admet-189	397	12	and	and	CCONJ
admet-189	397	13	lactoferrin	lactoferrin	NOUN
admet-189	397	14	conjugation	conjugation	NOUN
admet-189	397	15	facilitate	facilitate	VERB
admet-189	397	16	the	the	DET
admet-189	397	17	transport	transport	NOUN
admet-189	397	18	of	of	ADP
admet-189	397	19	mnps	mnps	PROPN
admet-189	397	20	across	across	ADP
admet-189	397	21	bbb	bbb	PROPN
admet-189	398	1	[	[	X
admet-189	398	2	99	99	NUM
admet-189	398	3	]	]	PUNCT
admet-189	398	4	.	.	PUNCT
admet-189	399	1	the	the	DET
admet-189	399	2	vascular	vascular	ADJ
admet-189	399	3	imaging	imaging	NOUN
admet-189	399	4	after	after	ADP
admet-189	399	5	intravenous	intravenous	ADJ
admet-189	399	6	injection	injection	NOUN
admet-189	399	7	of	of	ADP
admet-189	399	8	targeted	target	VERB
admet-189	399	9	mnps	mnps	NOUN
admet-189	399	10	confirm	confirm	VERB
admet-189	399	11	lactoferrin	lactoferrin	NOUN
admet-189	399	12	receptor	receptor	NOUN
admet-189	399	13	mediated	mediate	VERB
admet-189	399	14	transcytosis	transcytosis	NOUN
admet-189	399	15	with	with	ADP
admet-189	399	16	interaction	interaction	NOUN
admet-189	399	17	between	between	ADP
admet-189	399	18	targeted	target	VERB
admet-189	399	19	nanoparticles	nanoparticle	NOUN
admet-189	399	20	and	and	CCONJ
admet-189	399	21	lactoferrin	lactoferrin	NOUN
admet-189	399	22	receptors	receptor	NOUN
admet-189	399	23	expressed	express	VERB
admet-189	399	24	on	on	ADP
admet-189	399	25	microvascular	microvascular	ADJ
admet-189	399	26	endothelial	endothelial	ADJ
admet-189	399	27	cells	cell	NOUN
admet-189	399	28	[	[	X
admet-189	399	29	99	99	NUM
admet-189	399	30	]	]	PUNCT
admet-189	399	31	.	.	PUNCT
admet-189	400	1	recently	recently	ADV
admet-189	400	2	hwang	hwang	PROPN
admet-189	400	3	et	et	PROPN
admet-189	400	4	al	al	PROPN
admet-189	400	5	.	.	PROPN
admet-189	401	1	(	(	PUNCT
admet-189	401	2	2009	2009	NUM
admet-189	401	3	)	)	PUNCT
admet-189	401	4	reported	report	VERB
admet-189	401	5	ultrasound	ultrasound	ADJ
admet-189	401	6	responsive	responsive	ADJ
admet-189	401	7	stable	stable	ADJ
admet-189	401	8	perfluorocarbon	perfluorocarbon	NOUN
admet-189	401	9	nanobubbles	nanobubbles	PROPN
admet-189	401	10	(	(	PUNCT
admet-189	401	11	pns	pns	PROPN
admet-189	401	12	)	)	PUNCT
admet-189	401	13	loaded	load	VERB
admet-189	401	14	with	with	ADP
admet-189	401	15	dopamine	dopamine	NOUN
admet-189	401	16	receptor	receptor	NOUN
admet-189	401	17	agonist	agonist	NOUN
admet-189	401	18	(	(	PUNCT
admet-189	401	19	apomorphine	apomorphine	NOUN
admet-189	401	20	)	)	PUNCT
admet-189	401	21	for	for	ADP
admet-189	401	22	targeting	target	VERB
admet-189	401	23	the	the	DET
admet-189	401	24	brain	brain	NOUN
admet-189	401	25	.	.	PUNCT
admet-189	402	1	the	the	DET
admet-189	402	2	studies	study	NOUN
admet-189	402	3	showed	show	VERB
admet-189	402	4	the	the	DET
admet-189	402	5	improved	improved	ADJ
admet-189	402	6	stability	stability	NOUN
admet-189	402	7	and	and	CCONJ
admet-189	402	8	higher	high	ADJ
admet-189	402	9	plasma	plasma	NOUN
admet-189	402	10	residence	residence	NOUN
admet-189	402	11	time	time	NOUN
admet-189	402	12	of	of	ADP
admet-189	402	13	apomorphine	apomorphine	PROPN
admet-189	402	14	loaded	load	VERB
admet-189	402	15	pns	pns	PROPN
admet-189	402	16	in	in	ADP
admet-189	402	17	vivo	vivo	NOUN
admet-189	402	18	attributable	attributable	ADJ
admet-189	402	19	to	to	ADP
admet-189	402	20	rigid	rigid	ADJ
admet-189	402	21	cholesterol	cholesterol	NOUN
admet-189	402	22	and	and	CCONJ
admet-189	402	23	phospholipid	phospholipid	NOUN
admet-189	402	24	membrane	membrane	NOUN
admet-189	402	25	.	.	PUNCT
admet-189	403	1	ultrasound	ultrasound	NOUN
admet-189	403	2	trigger	trigger	NOUN
admet-189	403	3	altered	alter	VERB
admet-189	403	4	the	the	DET
admet-189	403	5	release	release	NOUN
admet-189	403	6	profiles	profile	NOUN
admet-189	403	7	on	on	ADP
admet-189	403	8	demand	demand	NOUN
admet-189	403	9	.	.	PUNCT
admet-189	404	1	erythrocyte	erythrocyte	ADJ
admet-189	404	2	hemolysis	hemolysis	NOUN
admet-189	404	3	study	study	NOUN
admet-189	404	4	demonstrated	demonstrate	VERB
admet-189	404	5	the	the	DET
admet-189	404	6	safety	safety	NOUN
admet-189	404	7	profile	profile	NOUN
admet-189	404	8	(	(	PUNCT
admet-189	404	9	<	<	X
admet-189	404	10	10	10	NUM
admet-189	404	11	%	%	NOUN
admet-189	404	12	hemolysis	hemolysis	NOUN
admet-189	404	13	)	)	PUNCT
admet-189	404	14	of	of	ADP
admet-189	404	15	pns	pns	PROPN
admet-189	404	16	[	[	X
admet-189	404	17	100	100	NUM
admet-189	404	18	]	]	PUNCT
admet-189	404	19	.	.	PUNCT
admet-189	405	1	altogether	altogether	ADV
admet-189	405	2	these	these	DET
admet-189	405	3	studies	study	NOUN
admet-189	405	4	revealed	reveal	VERB
admet-189	405	5	the	the	DET
admet-189	405	6	potential	potential	NOUN
admet-189	405	7	of	of	ADP
admet-189	405	8	stimulus	stimulus	ADJ
admet-189	405	9	sensitive	sensitive	ADJ
admet-189	405	10	nano	nano	NOUN
admet-189	405	11	-	-	PUNCT
admet-189	405	12	carriers	carrier	NOUN
admet-189	405	13	for	for	ADP
admet-189	405	14	improving	improve	VERB
admet-189	405	15	stability	stability	NOUN
admet-189	405	16	,	,	PUNCT
admet-189	405	17	administration	administration	NOUN
admet-189	405	18	frequency	frequency	NOUN
admet-189	405	19	and	and	CCONJ
admet-189	405	20	on	on	ADP
admet-189	405	21	-	-	PUNCT
admet-189	405	22	demand	demand	NOUN
admet-189	405	23	release	release	NOUN
admet-189	405	24	kinetics	kinetic	NOUN
admet-189	405	25	of	of	ADP
admet-189	405	26	therapeutics	therapeutic	NOUN
admet-189	405	27	against	against	ADP
admet-189	405	28	pd	pd	PROPN
admet-189	405	29	.	.	PUNCT
admet-189	406	1	a	a	DET
admet-189	406	2	brief	brief	ADJ
admet-189	406	3	representation	representation	NOUN
admet-189	406	4	of	of	ADP
admet-189	406	5	the	the	DET
admet-189	406	6	use	use	NOUN
admet-189	406	7	of	of	ADP
admet-189	406	8	nanobubbles	nanobubble	NOUN
admet-189	406	9	as	as	SCONJ
admet-189	406	10	stimulus	stimulus	NOUN
admet-189	406	11	-	-	PUNCT
admet-189	406	12	responsive	responsive	ADJ
admet-189	406	13	nanoparticles	nanoparticle	NOUN
admet-189	406	14	is	be	AUX
admet-189	406	15	provided	provide	VERB
admet-189	406	16	in	in	ADP
admet-189	406	17	figure	figure	NOUN
admet-189	406	18	6	6	NUM
admet-189	406	19	.	.	PUNCT
admet-189	406	20	r.	r.	PROPN
admet-189	406	21	banerjee	banerjee	PROPN
admet-189	406	22	et	et	PROPN
admet-189	406	23	al	al	PROPN
admet-189	406	24	.	.	PROPN
admet-189	406	25	admet	admet	PROPN
admet-189	406	26	&	&	CCONJ
admet-189	406	27	dmpk	dmpk	PROPN
admet-189	406	28	3(3	3(3	NUM
admet-189	406	29	)	)	PUNCT
admet-189	406	30	(	(	PUNCT
admet-189	406	31	2015	2015	NUM
admet-189	406	32	)	)	PUNCT
admet-189	406	33	155	155	NUM
admet-189	406	34	-	-	SYM
admet-189	406	35	181	181	NUM
admet-189	406	36	170	170	NUM
admet-189	406	37	figure	figure	NOUN
admet-189	406	38	6	6	NUM
admet-189	406	39	.	.	PUNCT
admet-189	407	1	use	use	NOUN
admet-189	407	2	of	of	ADP
admet-189	407	3	stimulus	stimulus	ADJ
admet-189	407	4	responsive	responsive	ADJ
admet-189	407	5	nanoparticles	nanoparticle	NOUN
admet-189	407	6	for	for	ADP
admet-189	407	7	drug	drug	NOUN
admet-189	407	8	delivery	delivery	NOUN
admet-189	407	9	in	in	ADP
admet-189	407	10	parkinson	parkinson	NOUN
admet-189	407	11	’s	’s	PART
admet-189	407	12	disease	disease	NOUN
admet-189	407	13	with	with	ADP
admet-189	407	14	ultrasound	ultrasound	ADJ
admet-189	407	15	(	(	PUNCT
admet-189	407	16	stimulus	stimulus	NOUN
admet-189	407	17	)	)	PUNCT
admet-189	407	18	responsive	responsive	ADJ
admet-189	407	19	nanobubbles	nanobubble	NOUN
admet-189	407	20	(	(	PUNCT
admet-189	407	21	nanoparticles	nanoparticle	NOUN
admet-189	407	22	)	)	PUNCT
admet-189	407	23	as	as	ADP
admet-189	407	24	an	an	DET
admet-189	407	25	example	example	NOUN
admet-189	407	26	neuroprotection	neuroprotection	NOUN
admet-189	407	27	neuroprotection	neuroprotection	NOUN
admet-189	407	28	is	be	AUX
admet-189	407	29	the	the	DET
admet-189	407	30	ability	ability	NOUN
admet-189	407	31	for	for	ADP
admet-189	407	32	a	a	DET
admet-189	407	33	treatment	treatment	NOUN
admet-189	407	34	to	to	PART
admet-189	407	35	prevent	prevent	VERB
admet-189	407	36	neuronal	neuronal	ADJ
admet-189	407	37	cell	cell	NOUN
admet-189	407	38	death	death	NOUN
admet-189	407	39	by	by	ADP
admet-189	407	40	inhibition	inhibition	NOUN
admet-189	407	41	of	of	ADP
admet-189	407	42	the	the	DET
admet-189	407	43	cascade	cascade	NOUN
admet-189	407	44	resulting	result	VERB
admet-189	407	45	in	in	ADP
admet-189	407	46	cell	cell	NOUN
admet-189	407	47	dysfunction	dysfunction	NOUN
admet-189	407	48	and	and	CCONJ
admet-189	407	49	eventually	eventually	ADV
admet-189	407	50	cell	cell	VERB
admet-189	407	51	death	death	NOUN
admet-189	407	52	.	.	PUNCT
admet-189	408	1	the	the	DET
admet-189	408	2	relevance	relevance	NOUN
admet-189	408	3	to	to	ADP
admet-189	408	4	pd	pd	PROPN
admet-189	408	5	lays	lay	VERB
admet-189	408	6	in	in	ADP
admet-189	408	7	the	the	DET
admet-189	408	8	fact	fact	NOUN
admet-189	408	9	that	that	SCONJ
admet-189	408	10	the	the	DET
admet-189	408	11	pathogenesis	pathogenesis	NOUN
admet-189	408	12	of	of	ADP
admet-189	408	13	pd	pd	PROPN
admet-189	408	14	involves	involve	VERB
admet-189	408	15	oxidative	oxidative	ADJ
admet-189	408	16	stress	stress	NOUN
admet-189	408	17	in	in	ADP
admet-189	408	18	substantia	substantia	NOUN
admet-189	408	19	nigra	nigra	VERB
admet-189	408	20	through	through	ADP
admet-189	408	21	production	production	NOUN
admet-189	408	22	of	of	ADP
admet-189	408	23	reactive	reactive	ADJ
admet-189	408	24	oxygen	oxygen	NOUN
admet-189	408	25	species	specie	NOUN
admet-189	408	26	(	(	PUNCT
admet-189	408	27	ros	ros	PROPN
admet-189	408	28	)	)	PUNCT
admet-189	408	29	and	and	CCONJ
admet-189	408	30	hydrogen	hydrogen	NOUN
admet-189	408	31	peroxide	peroxide	NOUN
admet-189	408	32	by	by	ADP
admet-189	408	33	extensive	extensive	ADJ
admet-189	408	34	oxidative	oxidative	ADJ
admet-189	408	35	metabolism	metabolism	NOUN
admet-189	408	36	of	of	ADP
admet-189	408	37	dopamine	dopamine	NOUN
admet-189	408	38	.	.	PUNCT
admet-189	409	1	neurotrophic	neurotrophic	ADJ
admet-189	409	2	factors	factor	NOUN
admet-189	409	3	(	(	PUNCT
admet-189	409	4	like	like	ADP
admet-189	409	5	glial	glial	ADJ
admet-189	409	6	cell	cell	NOUN
admet-189	409	7	derived	derive	VERB
admet-189	409	8	neurotrophic	neurotrophic	ADJ
admet-189	409	9	factor	factor	NOUN
admet-189	409	10	(	(	PUNCT
admet-189	409	11	gdnf	gdnf	PROPN
admet-189	409	12	)	)	PUNCT
admet-189	409	13	)	)	PUNCT
admet-189	409	14	,	,	PUNCT
admet-189	409	15	fullerenes	fullerene	NOUN
admet-189	409	16	and	and	CCONJ
admet-189	409	17	nanoceria	nanoceria	NOUN
admet-189	409	18	,	,	PUNCT
admet-189	409	19	show	show	VERB
admet-189	409	20	neuroprotection	neuroprotection	NOUN
admet-189	409	21	in	in	ADP
admet-189	409	22	pd	pd	PROPN
admet-189	410	1	[	[	X
admet-189	410	2	101,102	101,102	NUM
admet-189	410	3	]	]	PUNCT
admet-189	410	4	.	.	PUNCT
admet-189	411	1	the	the	DET
admet-189	411	2	response	response	NOUN
admet-189	411	3	from	from	ADP
admet-189	411	4	direct	direct	ADJ
admet-189	411	5	infusion	infusion	NOUN
admet-189	411	6	of	of	ADP
admet-189	411	7	gdnf	gdnf	NOUN
admet-189	411	8	to	to	ADP
admet-189	411	9	the	the	DET
admet-189	411	10	putamen	putaman	NOUN
admet-189	411	11	had	have	VERB
admet-189	411	12	initial	initial	ADJ
admet-189	411	13	success	success	NOUN
admet-189	411	14	but	but	CCONJ
admet-189	411	15	later	later	ADV
admet-189	411	16	could	could	AUX
admet-189	411	17	not	not	PART
admet-189	411	18	demonstrate	demonstrate	VERB
admet-189	411	19	any	any	DET
admet-189	411	20	significant	significant	ADJ
admet-189	411	21	benefits	benefit	NOUN
admet-189	411	22	in	in	ADP
admet-189	411	23	controlled	control	VERB
admet-189	411	24	clinical	clinical	ADJ
admet-189	411	25	trials	trial	NOUN
admet-189	411	26	due	due	ADP
admet-189	411	27	to	to	ADP
admet-189	411	28	development	development	NOUN
admet-189	411	29	of	of	ADP
admet-189	411	30	antibodies	antibody	NOUN
admet-189	411	31	and	and	CCONJ
admet-189	411	32	cerebellar	cerebellar	ADJ
admet-189	411	33	degeneration	degeneration	NOUN
admet-189	411	34	[	[	X
admet-189	411	35	103	103	NUM
admet-189	411	36	]	]	PUNCT
admet-189	411	37	.	.	PUNCT
admet-189	412	1	this	this	PRON
admet-189	412	2	called	call	VERB
admet-189	412	3	for	for	ADP
admet-189	412	4	better	well	ADJ
admet-189	412	5	modes	mode	NOUN
admet-189	412	6	of	of	ADP
admet-189	412	7	controlled	control	VERB
admet-189	412	8	delivery	delivery	NOUN
admet-189	412	9	of	of	ADP
admet-189	412	10	gdnf	gdnf	PROPN
admet-189	412	11	.	.	PUNCT
admet-189	413	1	wang	wang	PROPN
admet-189	413	2	et	et	PROPN
admet-189	413	3	al	al	PROPN
admet-189	413	4	.	.	PROPN
admet-189	413	5	described	describe	VERB
admet-189	413	6	the	the	DET
admet-189	413	7	use	use	NOUN
admet-189	413	8	of	of	ADP
admet-189	413	9	microbubbles	microbubble	NOUN
admet-189	413	10	loaded	load	VERB
admet-189	413	11	with	with	ADP
admet-189	413	12	gdnf	gdnf	NOUN
admet-189	413	13	which	which	PRON
admet-189	413	14	released	release	VERB
admet-189	413	15	gdnf	gdnf	NOUN
admet-189	413	16	on	on	ADP
admet-189	413	17	low	low	ADJ
admet-189	413	18	-	-	PUNCT
admet-189	413	19	frequency	frequency	NOUN
admet-189	413	20	ultrasound	ultrasound	NOUN
admet-189	413	21	stimulation	stimulation	NOUN
admet-189	413	22	in	in	ADP
admet-189	413	23	the	the	DET
admet-189	413	24	treatment	treatment	NOUN
admet-189	413	25	of	of	ADP
admet-189	413	26	pd	pd	NOUN
admet-189	413	27	-	-	VERB
admet-189	413	28	induced	induced	ADJ
admet-189	413	29	in	in	ADP
admet-189	413	30	rats	rat	NOUN
admet-189	413	31	[	[	X
admet-189	413	32	68	68	NUM
admet-189	413	33	]	]	PUNCT
admet-189	413	34	.	.	PUNCT
admet-189	414	1	gdnf	gdnf	PROPN
admet-189	414	2	levels	level	NOUN
admet-189	414	3	augmented	augment	VERB
admet-189	414	4	in	in	ADP
admet-189	414	5	the	the	DET
admet-189	414	6	striatum	striatum	NOUN
admet-189	414	7	following	follow	VERB
admet-189	414	8	low	low	ADJ
admet-189	414	9	frequency	frequency	NOUN
admet-189	414	10	ultrasound	ultrasound	NOUN
admet-189	414	11	stimulation	stimulation	NOUN
admet-189	414	12	after	after	ADP
admet-189	414	13	the	the	DET
admet-189	414	14	infusion	infusion	NOUN
admet-189	414	15	of	of	ADP
admet-189	414	16	microbubbles	microbubble	NOUN
admet-189	414	17	and	and	CCONJ
admet-189	414	18	resulted	result	VERB
admet-189	414	19	in	in	ADP
admet-189	414	20	favorable	favorable	ADJ
admet-189	414	21	biochemical	biochemical	ADJ
admet-189	414	22	and	and	CCONJ
admet-189	414	23	behavioral	behavioral	ADJ
admet-189	414	24	changes	change	NOUN
admet-189	414	25	suggesting	suggest	VERB
admet-189	414	26	neuroprotective	neuroprotective	ADJ
admet-189	414	27	effects	effect	NOUN
admet-189	414	28	[	[	X
admet-189	414	29	68	68	NUM
admet-189	414	30	]	]	PUNCT
admet-189	414	31	.	.	PUNCT
admet-189	415	1	thus	thus	ADV
admet-189	415	2	,	,	PUNCT
admet-189	415	3	ultrasound	ultrasound	ADJ
admet-189	415	4	responsive	responsive	ADJ
admet-189	415	5	nanoparticles	nanoparticle	NOUN
admet-189	415	6	can	can	AUX
admet-189	415	7	be	be	AUX
admet-189	415	8	of	of	ADP
admet-189	415	9	use	use	NOUN
admet-189	415	10	in	in	ADP
admet-189	415	11	the	the	DET
admet-189	415	12	theranostics	theranostic	NOUN
admet-189	415	13	of	of	ADP
admet-189	415	14	pdtherapy	pdtherapy	NOUN
admet-189	415	15	by	by	ADP
admet-189	415	16	drug	drug	NOUN
admet-189	415	17	delivery	delivery	NOUN
admet-189	415	18	and	and	CCONJ
admet-189	415	19	imaging	imaging	NOUN
admet-189	415	20	due	due	ADP
admet-189	415	21	to	to	ADP
admet-189	415	22	the	the	DET
admet-189	415	23	contrast	contrast	NOUN
admet-189	415	24	provided	provide	VERB
admet-189	415	25	by	by	ADP
admet-189	415	26	the	the	DET
admet-189	415	27	microbubbles	microbubble	NOUN
admet-189	415	28	.	.	PUNCT
admet-189	416	1	in	in	ADP
admet-189	416	2	another	another	DET
admet-189	416	3	approach	approach	NOUN
admet-189	416	4	,	,	PUNCT
admet-189	416	5	a	a	DET
admet-189	416	6	number	number	NOUN
admet-189	416	7	of	of	ADP
admet-189	416	8	non	non	ADJ
admet-189	416	9	-	-	ADJ
admet-189	416	10	viral	viral	ADJ
admet-189	416	11	gene	gene	NOUN
admet-189	416	12	delivery	delivery	NOUN
admet-189	416	13	vectors	vector	NOUN
admet-189	416	14	are	be	AUX
admet-189	416	15	being	be	AUX
admet-189	416	16	developed	develop	VERB
admet-189	416	17	that	that	PRON
admet-189	416	18	have	have	AUX
admet-189	416	19	reduced	reduce	VERB
admet-189	416	20	toxicities	toxicity	NOUN
admet-189	416	21	and	and	CCONJ
admet-189	416	22	have	have	VERB
admet-189	416	23	comparable	comparable	ADJ
admet-189	416	24	efficiencies	efficiency	NOUN
admet-189	416	25	in	in	ADP
admet-189	416	26	transferring	transfer	VERB
admet-189	416	27	gdnf	gdnf	ADJ
admet-189	416	28	genes	gene	NOUN
admet-189	416	29	into	into	ADP
admet-189	416	30	the	the	DET
admet-189	416	31	target	target	NOUN
admet-189	416	32	cells	cell	NOUN
admet-189	416	33	.	.	PUNCT
admet-189	417	1	as	as	SCONJ
admet-189	417	2	has	have	AUX
admet-189	417	3	been	be	AUX
admet-189	417	4	mentioned	mention	VERB
admet-189	417	5	earlier	early	ADV
admet-189	417	6	,	,	PUNCT
admet-189	417	7	lactoferrin	lactoferrin	NOUN
admet-189	417	8	-	-	PUNCT
admet-189	417	9	conjugated	conjugate	VERB
admet-189	417	10	nanoparticles	nanoparticle	NOUN
admet-189	417	11	have	have	AUX
admet-189	417	12	been	be	AUX
admet-189	417	13	used	use	VERB
admet-189	417	14	successfully	successfully	ADV
admet-189	417	15	for	for	ADP
admet-189	417	16	this	this	DET
admet-189	417	17	purpose	purpose	NOUN
admet-189	417	18	in	in	ADP
admet-189	417	19	pd	pd	X
admet-189	417	20	rat	rat	NOUN
admet-189	417	21	models	model	NOUN
admet-189	417	22	[	[	X
admet-189	417	23	104	104	NUM
admet-189	417	24	]	]	PUNCT
admet-189	417	25	.	.	PUNCT
admet-189	418	1	similarly	similarly	ADV
admet-189	418	2	,	,	PUNCT
admet-189	418	3	angiopep	angiopep	PROPN
admet-189	418	4	with	with	ADP
admet-189	418	5	a	a	DET
admet-189	418	6	sequence	sequence	NOUN
admet-189	418	7	of	of	ADP
admet-189	418	8	tffyggsrgkrnnfkteeyc	tffyggsrgkrnnfkteeyc	NOUN
admet-189	418	9	as	as	ADP
admet-189	418	10	the	the	DET
admet-189	418	11	targeting	targeting	NOUN
admet-189	418	12	ligand	ligand	NOUN
admet-189	418	13	to	to	PART
admet-189	418	14	mediate	mediate	VERB
admet-189	418	15	bbb	bbb	PROPN
admet-189	418	16	transport	transport	NOUN
admet-189	418	17	and	and	CCONJ
admet-189	418	18	cellular	cellular	ADJ
admet-189	418	19	internalization	internalization	NOUN
admet-189	418	20	was	be	AUX
admet-189	418	21	conjugated	conjugate	VERB
admet-189	418	22	to	to	ADP
admet-189	418	23	poly	poly	ADJ
admet-189	418	24	-	-	PUNCT
admet-189	418	25	l	l	NOUN
admet-189	418	26	-	-	PUNCT
admet-189	418	27	lysine	lysine	NOUN
admet-189	418	28	-	-	PUNCT
admet-189	418	29	based	base	VERB
admet-189	418	30	dendrimer	dendrimer	NOUN
admet-189	418	31	nanoparticles	nanoparticle	NOUN
admet-189	418	32	(	(	PUNCT
admet-189	418	33	dendrigraft	dendrigraft	NOUN
admet-189	418	34	poly	poly	ADJ
admet-189	418	35	-	-	PUNCT
admet-189	418	36	l	l	NOUN
admet-189	418	37	-	-	NOUN
admet-189	418	38	lysine	lysine	NOUN
admet-189	418	39	)	)	PUNCT
admet-189	418	40	via	via	ADP
admet-189	418	41	hydrophilic	hydrophilic	ADJ
admet-189	418	42	polyethylene	polyethylene	NOUN
admet-189	418	43	glycol	glycol	NOUN
admet-189	418	44	(	(	PUNCT
admet-189	418	45	peg	peg	NOUN
admet-189	418	46	)	)	PUNCT
admet-189	419	1	[	[	X
admet-189	419	2	105	105	NUM
admet-189	419	3	]	]	PUNCT
admet-189	419	4	.	.	PUNCT
admet-189	420	1	these	these	DET
admet-189	420	2	nanoparticles	nanoparticle	NOUN
admet-189	420	3	constructs	construct	NOUN
admet-189	420	4	allowed	allow	VERB
admet-189	420	5	effective	effective	ADJ
admet-189	420	6	gene	gene	NOUN
admet-189	420	7	expression	expression	NOUN
admet-189	420	8	both	both	CCONJ
admet-189	420	9	in	in	ADP
admet-189	420	10	vitro	vitro	X
admet-189	420	11	and	and	CCONJ
admet-189	420	12	in	in	ADP
admet-189	420	13	rat	rat	NOUN
admet-189	420	14	models	model	NOUN
admet-189	420	15	of	of	ADP
admet-189	420	16	pd	pd	PROPN
admet-189	421	1	[	[	X
admet-189	421	2	105	105	NUM
admet-189	421	3	]	]	PUNCT
admet-189	421	4	.	.	PUNCT
admet-189	422	1	in	in	ADP
admet-189	422	2	addition	addition	NOUN
admet-189	422	3	to	to	ADP
admet-189	422	4	the	the	DET
admet-189	422	5	delivery	delivery	NOUN
admet-189	422	6	of	of	ADP
admet-189	422	7	neurotrophic	neurotrophic	ADJ
admet-189	422	8	factors	factor	NOUN
admet-189	422	9	,	,	PUNCT
admet-189	422	10	the	the	DET
admet-189	422	11	use	use	NOUN
admet-189	422	12	of	of	ADP
admet-189	422	13	fullerenes	fullerene	NOUN
admet-189	422	14	and	and	CCONJ
admet-189	422	15	nanoceria	nanoceria	NOUN
admet-189	422	16	is	be	AUX
admet-189	422	17	of	of	ADP
admet-189	422	18	great	great	ADJ
admet-189	422	19	interest	interest	NOUN
admet-189	422	20	.	.	PUNCT
admet-189	423	1	pretreatment	pretreatment	NOUN
admet-189	423	2	with	with	ADP
admet-189	423	3	polyhydroxylated	polyhydroxylate	VERB
admet-189	423	4	fullerene	fullerene	NOUN
admet-189	423	5	derivative	derivative	NOUN
admet-189	423	6	c(60)(oh)(24	c(60)(oh)(24	NUM
admet-189	423	7	)	)	PUNCT
admet-189	423	8	at	at	ADP
admet-189	423	9	≥20	≥20	NOUN
admet-189	423	10	µm	µm	ADP
admet-189	423	11	concentrations	concentration	NOUN
admet-189	423	12	were	be	AUX
admet-189	423	13	used	use	VERB
admet-189	423	14	by	by	ADP
admet-189	423	15	cai	cai	PROPN
admet-189	423	16	et	et	PROPN
admet-189	423	17	al	al	PROPN
admet-189	423	18	.	.	PROPN
admet-189	424	1	for	for	ADP
admet-189	424	2	the	the	DET
admet-189	424	3	purposes	purpose	NOUN
admet-189	424	4	of	of	ADP
admet-189	424	5	neuroprotection	neuroprotection	NOUN
admet-189	424	6	[	[	X
admet-189	424	7	106	106	NUM
admet-189	424	8	]	]	PUNCT
admet-189	424	9	.	.	PUNCT
admet-189	425	1	in	in	ADP
admet-189	425	2	an	an	DET
admet-189	425	3	in	in	X
admet-189	425	4	vitro	vitro	X
admet-189	425	5	cellular	cellular	ADJ
admet-189	425	6	model	model	NOUN
admet-189	425	7	of	of	ADP
admet-189	425	8	parkinson	parkinson	NOUN
admet-189	425	9	's	's	PART
admet-189	425	10	disease	disease	NOUN
admet-189	425	11	,	,	PUNCT
admet-189	425	12	significant	significant	ADJ
admet-189	425	13	protective	protective	ADJ
admet-189	425	14	effects	effect	NOUN
admet-189	425	15	as	as	SCONJ
admet-189	425	16	reflected	reflect	VERB
admet-189	425	17	by	by	ADP
admet-189	425	18	cell	cell	NOUN
admet-189	425	19	viability	viability	NOUN
admet-189	425	20	,	,	PUNCT
admet-189	425	21	mitochondrial	mitochondrial	ADJ
admet-189	425	22	function	function	NOUN
admet-189	425	23	;	;	PUNCT
admet-189	425	24	levels	level	NOUN
admet-189	425	25	of	of	ADP
admet-189	425	26	reactive	reactive	ADJ
admet-189	425	27	oxygen	oxygen	NOUN
admet-189	425	28	species	specie	NOUN
admet-189	425	29	decreased	decrease	VERB
admet-189	425	30	and	and	CCONJ
admet-189	425	31	dna	dna	NOUN
admet-189	425	32	and	and	CCONJ
admet-189	425	33	proteins	protein	NOUN
admet-189	425	34	damage	damage	NOUN
admet-189	425	35	were	be	AUX
admet-189	425	36	reduced	reduce	VERB
admet-189	425	37	with	with	ADP
admet-189	425	38	polyhydroxylated	polyhydroxylate	VERB
admet-189	425	39	fullerenes	fullerene	NOUN
admet-189	426	1	[	[	X
admet-189	426	2	106	106	NUM
admet-189	426	3	]	]	PUNCT
admet-189	426	4	.	.	PUNCT
admet-189	427	1	also	also	ADV
admet-189	427	2	,	,	PUNCT
admet-189	427	3	fullerenes	fullerene	NOUN
admet-189	427	4	in	in	ADP
admet-189	427	5	the	the	DET
admet-189	427	6	form	form	NOUN
admet-189	427	7	of	of	ADP
admet-189	427	8	carboxyfullerenes	carboxyfullerene	NOUN
admet-189	427	9	(	(	PUNCT
admet-189	427	10	c3	c3	PROPN
admet-189	427	11	)	)	PUNCT
admet-189	427	12	showed	show	VERB
admet-189	427	13	neuroprotection	neuroprotection	NOUN
admet-189	427	14	in	in	ADP
admet-189	427	15	macaque	macaque	ADJ
admet-189	427	16	fascicularis	fascicularis	NOUN
admet-189	427	17	monkeys	monkey	NOUN
admet-189	427	18	[	[	X
admet-189	427	19	107	107	NUM
admet-189	427	20	]	]	PUNCT
admet-189	427	21	.	.	PUNCT
admet-189	428	1	the	the	DET
admet-189	428	2	technology	technology	NOUN
admet-189	428	3	leveraging	leverage	VERB
admet-189	428	4	the	the	DET
admet-189	428	5	antioxidant	antioxidant	ADJ
admet-189	428	6	properties	property	NOUN
admet-189	428	7	of	of	ADP
admet-189	428	8	fullerenes	fullerene	NOUN
admet-189	428	9	in	in	ADP
admet-189	428	10	the	the	DET
admet-189	428	11	treatment	treatment	NOUN
admet-189	428	12	of	of	ADP
admet-189	428	13	parkinson	parkinson	NOUN
admet-189	428	14	's	's	PART
admet-189	428	15	disease	disease	NOUN
admet-189	428	16	is	be	AUX
admet-189	428	17	being	be	AUX
admet-189	428	18	commercialized	commercialize	VERB
admet-189	428	19	and	and	CCONJ
admet-189	428	20	the	the	DET
admet-189	428	21	leading	lead	VERB
admet-189	428	22	companies	company	NOUN
admet-189	428	23	involved	involve	VERB
admet-189	428	24	are	be	AUX
admet-189	428	25	the	the	DET
admet-189	428	26	admet	admet	PROPN
admet-189	428	27	&	&	CCONJ
admet-189	428	28	dmpk	dmpk	PROPN
admet-189	428	29	3(3	3(3	NUM
admet-189	428	30	)	)	PUNCT
admet-189	428	31	(	(	PUNCT
admet-189	428	32	2015	2015	NUM
admet-189	428	33	)	)	PUNCT
admet-189	428	34	155	155	NUM
admet-189	428	35	-	-	SYM
admet-189	428	36	181	181	NUM
admet-189	428	37	nanotechnology	nanotechnology	NOUN
admet-189	428	38	platforms	platform	NOUN
admet-189	428	39	in	in	ADP
admet-189	428	40	parkinson	parkinson	NOUN
admet-189	428	41	’s	’s	PART
admet-189	428	42	disease	disease	NOUN
admet-189	428	43	doi	doi	NOUN
admet-189	428	44	:	:	PUNCT
admet-189	428	45	10.5599	10.5599	NUM
admet-189	428	46	/	/	SYM
admet-189	428	47	admet.3.3.189	admet.3.3.189	ADP
admet-189	428	48	171	171	NUM
admet-189	428	49	bronx	bronx	PROPN
admet-189	428	50	project	project	NOUN
admet-189	428	51	,	,	PUNCT
admet-189	428	52	inc	inc	PROPN
admet-189	428	53	.	.	PROPN
admet-189	428	54	(	(	PUNCT
admet-189	428	55	tbp	tbp	NOUN
admet-189	428	56	)	)	PUNCT
admet-189	428	57	,	,	PUNCT
admet-189	429	1	tego	tego	PROPN
admet-189	429	2	biosciences	biosciences	PROPN
admet-189	429	3	corporation	corporation	PROPN
admet-189	429	4	(	(	PUNCT
admet-189	429	5	tego	tego	NOUN
admet-189	429	6	)	)	PUNCT
admet-189	429	7	and	and	CCONJ
admet-189	429	8	luna	luna	PROPN
admet-189	429	9	innovations	innovation	NOUN
admet-189	429	10	incorporated	incorporate	VERB
admet-189	429	11	(	(	PUNCT
admet-189	429	12	luna	luna	PROPN
admet-189	429	13	)	)	PUNCT
admet-189	430	1	[	[	X
admet-189	430	2	108	108	NUM
admet-189	430	3	]	]	PUNCT
admet-189	430	4	.	.	PUNCT
admet-189	431	1	in	in	ADP
admet-189	431	2	addition	addition	NOUN
admet-189	431	3	to	to	ADP
admet-189	431	4	this	this	PRON
admet-189	431	5	,	,	PUNCT
admet-189	431	6	cerium	cerium	NOUN
admet-189	431	7	oxide	oxide	NOUN
admet-189	431	8	(	(	PUNCT
admet-189	431	9	ceo2	ceo2	NOUN
admet-189	431	10	)	)	PUNCT
admet-189	431	11	is	be	AUX
admet-189	431	12	being	be	AUX
admet-189	431	13	used	use	VERB
admet-189	431	14	for	for	ADP
admet-189	431	15	its	its	PRON
admet-189	431	16	capability	capability	NOUN
admet-189	431	17	of	of	ADP
admet-189	431	18	neutralizing	neutralize	VERB
admet-189	431	19	and	and	CCONJ
admet-189	431	20	reducing	reduce	VERB
admet-189	431	21	harmful	harmful	ADJ
admet-189	431	22	reactive	reactive	ADJ
admet-189	431	23	oxygen	oxygen	NOUN
admet-189	431	24	species	specie	NOUN
admet-189	431	25	in	in	ADP
admet-189	431	26	a	a	DET
admet-189	431	27	redox	redox	ADJ
admet-189	431	28	reaction	reaction	NOUN
admet-189	431	29	[	[	X
admet-189	431	30	102	102	NUM
admet-189	431	31	]	]	PUNCT
admet-189	431	32	.	.	PUNCT
admet-189	432	1	due	due	ADP
admet-189	432	2	to	to	ADP
admet-189	432	3	the	the	DET
admet-189	432	4	oxygen	oxygen	NOUN
admet-189	432	5	vacancies	vacancy	NOUN
admet-189	432	6	on	on	ADP
admet-189	432	7	the	the	DET
admet-189	432	8	ceo2	ceo2	NOUN
admet-189	432	9	surface	surface	NOUN
admet-189	432	10	and	and	CCONJ
admet-189	432	11	presence	presence	NOUN
admet-189	432	12	of	of	ADP
admet-189	432	13	both	both	CCONJ
admet-189	432	14	trivalent	trivalent	NOUN
admet-189	432	15	and	and	CCONJ
admet-189	432	16	tetravalent	tetravalent	NOUN
admet-189	432	17	states	state	NOUN
admet-189	432	18	of	of	ADP
admet-189	432	19	cerium	cerium	NOUN
admet-189	432	20	ions	ion	NOUN
admet-189	432	21	,	,	PUNCT
admet-189	432	22	during	during	ADP
admet-189	432	23	the	the	DET
admet-189	432	24	redox	redox	NOUN
admet-189	432	25	reaction	reaction	NOUN
admet-189	432	26	the	the	DET
admet-189	432	27	ions	ion	NOUN
admet-189	432	28	can	can	AUX
admet-189	432	29	flip	flip	VERB
admet-189	432	30	-	-	PUNCT
admet-189	432	31	flop	flop	NOUN
admet-189	432	32	between	between	ADP
admet-189	432	33	the	the	DET
admet-189	432	34	two	two	NUM
admet-189	432	35	oxidation	oxidation	NOUN
admet-189	432	36	states	state	NOUN
admet-189	432	37	[	[	X
admet-189	432	38	102	102	NUM
admet-189	432	39	]	]	PUNCT
admet-189	432	40	.	.	PUNCT
admet-189	433	1	leveraging	leverage	VERB
admet-189	433	2	this	this	DET
admet-189	433	3	scavenging	scavenge	VERB
admet-189	433	4	role	role	NOUN
admet-189	433	5	of	of	ADP
admet-189	433	6	cerium	cerium	ADJ
admet-189	433	7	oxide	oxide	NOUN
admet-189	433	8	,	,	PUNCT
admet-189	433	9	pinna	pinna	NOUN
admet-189	433	10	et	et	PROPN
admet-189	433	11	al	al	PROPN
admet-189	433	12	.	.	PROPN
admet-189	433	13	showed	show	VERB
admet-189	433	14	a	a	DET
admet-189	433	15	protective	protective	ADJ
admet-189	433	16	role	role	NOUN
admet-189	433	17	of	of	ADP
admet-189	433	18	nanoceria	nanoceria	NOUN
admet-189	433	19	both	both	CCONJ
admet-189	433	20	in	in	ADP
admet-189	433	21	vitro	vitro	X
admet-189	433	22	on	on	ADP
admet-189	433	23	pc12	pc12	PROPN
admet-189	433	24	cells	cell	NOUN
admet-189	433	25	survival	survival	NOUN
admet-189	433	26	and	and	CCONJ
admet-189	433	27	dopamine	dopamine	NOUN
admet-189	433	28	metabolism	metabolism	NOUN
admet-189	433	29	in	in	ADP
admet-189	433	30	manganese	manganese	NOUN
admet-189	433	31	-	-	PUNCT
admet-189	433	32	induced	induce	VERB
admet-189	433	33	parkinson	parkinson	NOUN
admet-189	433	34	’s	’s	PART
admet-189	433	35	disease	disease	NOUN
admet-189	433	36	[	[	X
admet-189	433	37	102	102	NUM
admet-189	433	38	]	]	PUNCT
admet-189	433	39	.	.	PUNCT
admet-189	434	1	other	other	ADJ
admet-189	434	2	approaches	approach	NOUN
admet-189	434	3	in	in	ADP
admet-189	434	4	management	management	NOUN
admet-189	434	5	of	of	ADP
admet-189	434	6	parkinson	parkinson	NOUN
admet-189	434	7	’s	’s	PART
admet-189	434	8	disease	disease	NOUN
admet-189	434	9	based	base	VERB
admet-189	434	10	on	on	ADP
admet-189	434	11	nanotechnology	nanotechnology	PROPN
admet-189	434	12	neural	neural	ADJ
admet-189	434	13	prosthetic	prosthetic	ADJ
admet-189	434	14	electrodes	electrode	NOUN
admet-189	434	15	for	for	ADP
admet-189	434	16	deep	deep	ADJ
admet-189	434	17	brain	brain	NOUN
admet-189	434	18	stimulation	stimulation	NOUN
admet-189	434	19	bilateral	bilateral	ADJ
admet-189	434	20	deep	deep	ADJ
admet-189	434	21	brain	brain	NOUN
admet-189	434	22	stimulation	stimulation	NOUN
admet-189	434	23	(	(	PUNCT
admet-189	434	24	dbs	dbs	PROPN
admet-189	434	25	)	)	PUNCT
admet-189	434	26	of	of	ADP
admet-189	434	27	the	the	DET
admet-189	434	28	subthalamic	subthalamic	ADJ
admet-189	434	29	nucleus	nucleus	NOUN
admet-189	434	30	(	(	PUNCT
admet-189	434	31	stn	stn	PROPN
admet-189	434	32	)	)	PUNCT
admet-189	434	33	through	through	ADP
admet-189	434	34	electrical	electrical	ADJ
admet-189	434	35	stimulation	stimulation	NOUN
admet-189	434	36	using	use	VERB
admet-189	434	37	implanted	implant	VERB
admet-189	434	38	neural	neural	ADJ
admet-189	434	39	prosthetic	prosthetic	ADJ
admet-189	434	40	electrodes	electrode	NOUN
admet-189	434	41	is	be	AUX
admet-189	434	42	a	a	DET
admet-189	434	43	proven	proven	ADJ
admet-189	434	44	and	and	CCONJ
admet-189	434	45	fda	fda	PROPN
admet-189	434	46	-	-	PUNCT
admet-189	434	47	approved	approve	VERB
admet-189	434	48	treatment	treatment	NOUN
admet-189	434	49	modality	modality	NOUN
admet-189	434	50	for	for	ADP
admet-189	434	51	advanced	advanced	ADJ
admet-189	434	52	parkinson	parkinson	NOUN
admet-189	434	53	's	's	PART
admet-189	434	54	disease	disease	NOUN
admet-189	434	55	[	[	X
admet-189	434	56	109	109	NUM
admet-189	434	57	]	]	PUNCT
admet-189	434	58	.	.	PUNCT
admet-189	435	1	deep	deep	ADJ
admet-189	435	2	brain	brain	NOUN
admet-189	435	3	stimulation	stimulation	NOUN
admet-189	435	4	has	have	AUX
admet-189	435	5	been	be	AUX
admet-189	435	6	found	find	VERB
admet-189	435	7	to	to	PART
admet-189	435	8	be	be	AUX
admet-189	435	9	better	well	ADJ
admet-189	435	10	than	than	ADP
admet-189	435	11	medical	medical	ADJ
admet-189	435	12	therapy	therapy	NOUN
admet-189	435	13	in	in	ADP
admet-189	435	14	producing	produce	VERB
admet-189	435	15	improvements	improvement	NOUN
admet-189	435	16	in	in	ADP
admet-189	435	17	motor	motor	NOUN
admet-189	435	18	symptoms	symptom	NOUN
admet-189	435	19	[	[	X
admet-189	435	20	109,110	109,110	NUM
admet-189	435	21	]	]	PUNCT
admet-189	435	22	.	.	PUNCT
admet-189	436	1	however	however	ADV
admet-189	436	2	,	,	PUNCT
admet-189	436	3	the	the	DET
admet-189	436	4	precision	precision	NOUN
admet-189	436	5	of	of	ADP
admet-189	436	6	dbs	dbs	PROPN
admet-189	436	7	is	be	AUX
admet-189	436	8	an	an	DET
admet-189	436	9	important	important	ADJ
admet-189	436	10	issue	issue	NOUN
admet-189	436	11	that	that	PRON
admet-189	436	12	needs	need	VERB
admet-189	436	13	to	to	PART
admet-189	436	14	be	be	AUX
admet-189	436	15	tweaked	tweak	VERB
admet-189	436	16	to	to	PART
admet-189	436	17	address	address	VERB
admet-189	436	18	the	the	DET
admet-189	436	19	ethical	ethical	ADJ
admet-189	436	20	implications	implication	NOUN
admet-189	436	21	of	of	ADP
admet-189	436	22	altering	alter	VERB
admet-189	436	23	brain	brain	NOUN
admet-189	436	24	circuits	circuit	NOUN
admet-189	436	25	with	with	ADP
admet-189	436	26	this	this	DET
admet-189	436	27	technique	technique	NOUN
admet-189	436	28	[	[	X
admet-189	436	29	111	111	NUM
admet-189	436	30	]	]	PUNCT
admet-189	436	31	.	.	PUNCT
admet-189	437	1	for	for	ADP
admet-189	437	2	this	this	DET
admet-189	437	3	purpose	purpose	NOUN
admet-189	437	4	,	,	PUNCT
admet-189	437	5	neural	neural	ADJ
admet-189	437	6	stimulation	stimulation	NOUN
admet-189	437	7	has	have	AUX
admet-189	437	8	employed	employ	VERB
admet-189	437	9	a	a	DET
admet-189	437	10	wide	wide	ADJ
admet-189	437	11	range	range	NOUN
admet-189	437	12	of	of	ADP
admet-189	437	13	metals	metal	NOUN
admet-189	437	14	and	and	CCONJ
admet-189	437	15	metal	metal	NOUN
admet-189	437	16	alloys	alloy	NOUN
admet-189	437	17	as	as	ADP
admet-189	437	18	materials	material	NOUN
admet-189	437	19	for	for	ADP
admet-189	437	20	fabrication	fabrication	NOUN
admet-189	437	21	of	of	ADP
admet-189	437	22	electrodes	electrode	NOUN
admet-189	437	23	in	in	ADP
admet-189	437	24	neural	neural	ADJ
admet-189	437	25	stimulation	stimulation	NOUN
admet-189	437	26	.	.	PUNCT
admet-189	438	1	these	these	PRON
admet-189	438	2	include	include	VERB
admet-189	438	3	noble	noble	ADJ
admet-189	438	4	metals	metal	NOUN
admet-189	438	5	(	(	PUNCT
admet-189	438	6	platinum	platinum	NOUN
admet-189	438	7	)	)	PUNCT
admet-189	438	8	,	,	PUNCT
admet-189	438	9	titanium	titanium	NOUN
admet-189	438	10	oxide	oxide	NOUN
admet-189	438	11	,	,	PUNCT
admet-189	438	12	activated	activate	VERB
admet-189	438	13	iridium	iridium	NOUN
admet-189	438	14	,	,	PUNCT
admet-189	438	15	tantalum	tantalum	NOUN
admet-189	438	16	oxide	oxide	NOUN
admet-189	438	17	,	,	PUNCT
admet-189	438	18	and	and	CCONJ
admet-189	438	19	silicon	silicon	NOUN
admet-189	439	1	[	[	X
admet-189	439	2	112	112	NUM
admet-189	439	3	]	]	PUNCT
admet-189	439	4	.	.	PUNCT
admet-189	440	1	however	however	ADV
admet-189	440	2	,	,	PUNCT
admet-189	440	3	these	these	DET
admet-189	440	4	materials	material	NOUN
admet-189	440	5	include	include	VERB
admet-189	440	6	limitations	limitation	NOUN
admet-189	440	7	in	in	ADP
admet-189	440	8	the	the	DET
admet-189	440	9	form	form	NOUN
admet-189	440	10	of	of	ADP
admet-189	440	11	low	low	ADJ
admet-189	440	12	charge	charge	NOUN
admet-189	440	13	injection	injection	NOUN
admet-189	440	14	limit	limit	NOUN
admet-189	440	15	allowing	allow	VERB
admet-189	440	16	only	only	ADV
admet-189	440	17	large	large	ADJ
admet-189	440	18	electrodes	electrode	NOUN
admet-189	440	19	with	with	ADP
admet-189	440	20	low	low	ADJ
admet-189	440	21	current	current	ADJ
admet-189	440	22	density	density	NOUN
admet-189	440	23	to	to	PART
admet-189	440	24	be	be	AUX
admet-189	440	25	used	use	VERB
admet-189	440	26	[	[	PUNCT
admet-189	440	27	113	113	NUM
admet-189	440	28	]	]	PUNCT
admet-189	440	29	,	,	PUNCT
admet-189	440	30	faradaic	faradaic	ADJ
admet-189	440	31	reactions	reaction	NOUN
admet-189	440	32	(	(	PUNCT
admet-189	440	33	consisting	consist	VERB
admet-189	440	34	of	of	ADP
admet-189	440	35	electron	electron	NOUN
admet-189	440	36	transfer	transfer	NOUN
admet-189	440	37	between	between	ADP
admet-189	440	38	electrode	electrode	NOUN
admet-189	440	39	and	and	CCONJ
admet-189	440	40	electrolyte	electrolyte	NOUN
admet-189	440	41	resulting	result	VERB
admet-189	440	42	in	in	ADP
admet-189	440	43	either	either	DET
admet-189	440	44	reduction	reduction	NOUN
admet-189	440	45	or	or	CCONJ
admet-189	440	46	oxidation	oxidation	NOUN
admet-189	440	47	of	of	ADP
admet-189	440	48	a	a	DET
admet-189	440	49	particular	particular	ADJ
admet-189	440	50	chemical	chemical	NOUN
admet-189	440	51	species	specie	NOUN
admet-189	440	52	in	in	ADP
admet-189	440	53	a	a	DET
admet-189	440	54	given	give	VERB
admet-189	440	55	electrolyte	electrolyte	NOUN
admet-189	440	56	)	)	PUNCT
admet-189	440	57	leading	lead	VERB
admet-189	440	58	to	to	ADP
admet-189	440	59	diffusion	diffusion	NOUN
admet-189	440	60	of	of	ADP
admet-189	440	61	toxic	toxic	ADJ
admet-189	440	62	products	product	NOUN
admet-189	440	63	or	or	CCONJ
admet-189	440	64	the	the	DET
admet-189	440	65	corrosion	corrosion	NOUN
admet-189	440	66	of	of	ADP
admet-189	440	67	electrodes	electrode	NOUN
admet-189	440	68	[	[	X
admet-189	440	69	114	114	NUM
admet-189	440	70	]	]	PUNCT
admet-189	440	71	as	as	ADV
admet-189	440	72	well	well	ADV
admet-189	440	73	as	as	ADP
admet-189	440	74	issues	issue	NOUN
admet-189	440	75	with	with	ADP
admet-189	440	76	biocompatibility	biocompatibility	NOUN
admet-189	440	77	with	with	ADP
admet-189	440	78	the	the	DET
admet-189	440	79	electrode	electrode	NOUN
admet-189	440	80	materials	material	NOUN
admet-189	440	81	[	[	X
admet-189	440	82	114	114	NUM
admet-189	440	83	]	]	PUNCT
admet-189	440	84	.	.	PUNCT
admet-189	441	1	carbon	carbon	NOUN
admet-189	441	2	nanotubesone	nanotubesone	NOUN
admet-189	441	3	of	of	ADP
admet-189	441	4	the	the	DET
admet-189	441	5	most	most	ADV
admet-189	441	6	versatile	versatile	ADJ
admet-189	441	7	nanotechnology	nanotechnology	NOUN
admet-189	441	8	options	option	NOUN
admet-189	441	9	explored	explore	VERB
admet-189	441	10	for	for	ADP
admet-189	441	11	neural	neural	ADJ
admet-189	441	12	prosthetic	prosthetic	ADJ
admet-189	441	13	electrodes	electrode	NOUN
admet-189	441	14	are	be	AUX
admet-189	441	15	carbon	carbon	NOUN
admet-189	441	16	nanotubes	nanotube	NOUN
admet-189	441	17	(	(	PUNCT
admet-189	441	18	cnts	cnts	PROPN
admet-189	441	19	)	)	PUNCT
admet-189	441	20	which	which	PRON
admet-189	441	21	have	have	VERB
admet-189	441	22	the	the	DET
admet-189	441	23	unique	unique	ADJ
admet-189	441	24	combination	combination	NOUN
admet-189	441	25	of	of	ADP
admet-189	441	26	being	be	AUX
admet-189	441	27	strong	strong	ADJ
admet-189	441	28	(	(	PUNCT
admet-189	441	29	young	young	PROPN
admet-189	441	30	’s	’s	PART
admet-189	441	31	modulus	modulus	NOUN
admet-189	441	32	more	more	ADJ
admet-189	441	33	than	than	ADP
admet-189	441	34	1	1	NUM
admet-189	441	35	tpa	tpa	NOUN
admet-189	441	36	)	)	PUNCT
admet-189	441	37	as	as	ADV
admet-189	441	38	well	well	ADV
admet-189	441	39	as	as	ADP
admet-189	441	40	flexible	flexible	ADJ
admet-189	441	41	.	.	PUNCT
admet-189	442	1	both	both	PRON
admet-189	442	2	of	of	ADP
admet-189	442	3	these	these	PRON
admet-189	442	4	are	be	AUX
admet-189	442	5	extremely	extremely	ADV
admet-189	442	6	important	important	ADJ
admet-189	442	7	for	for	ADP
admet-189	442	8	fabrication	fabrication	NOUN
admet-189	442	9	of	of	ADP
admet-189	442	10	penetrating	penetrate	VERB
admet-189	442	11	electrodes	electrode	NOUN
admet-189	442	12	in	in	ADP
admet-189	442	13	neural	neural	ADJ
admet-189	442	14	prostheses	prosthesis	NOUN
admet-189	442	15	[	[	X
admet-189	442	16	114	114	NUM
admet-189	442	17	]	]	PUNCT
admet-189	442	18	.	.	PUNCT
admet-189	443	1	besides	besides	SCONJ
admet-189	443	2	,	,	PUNCT
admet-189	443	3	to	to	PART
admet-189	443	4	serve	serve	VERB
admet-189	443	5	as	as	ADP
admet-189	443	6	an	an	DET
admet-189	443	7	electrode	electrode	NOUN
admet-189	443	8	for	for	ADP
admet-189	443	9	neural	neural	ADJ
admet-189	443	10	stimulation	stimulation	NOUN
admet-189	443	11	it	it	PRON
admet-189	443	12	should	should	AUX
admet-189	443	13	be	be	AUX
admet-189	443	14	able	able	ADJ
admet-189	443	15	to	to	PART
admet-189	443	16	deal	deal	VERB
admet-189	443	17	with	with	ADP
admet-189	443	18	the	the	DET
admet-189	443	19	critical	critical	ADJ
admet-189	443	20	trade	trade	NOUN
admet-189	443	21	-	-	PUNCT
admet-189	443	22	off	off	NOUN
admet-189	443	23	between	between	ADP
admet-189	443	24	high	high	ADJ
admet-189	443	25	charge	charge	NOUN
admet-189	443	26	injection	injection	NOUN
admet-189	443	27	limit	limit	NOUN
admet-189	443	28	and	and	CCONJ
admet-189	443	29	absence	absence	NOUN
admet-189	443	30	of	of	ADP
admet-189	443	31	faradaic	faradaic	ADJ
admet-189	443	32	reactions	reaction	NOUN
admet-189	443	33	.	.	PUNCT
admet-189	444	1	wang	wang	PROPN
admet-189	444	2	et	et	PROPN
admet-189	444	3	al	al	PROPN
admet-189	444	4	.	.	PROPN
admet-189	444	5	used	use	VERB
admet-189	444	6	multiwalled	multiwalle	VERB
admet-189	444	7	carbon	carbon	NOUN
admet-189	444	8	nanotube	nanotube	NOUN
admet-189	444	9	(	(	PUNCT
admet-189	444	10	cnt	cnt	ADJ
admet-189	444	11	)	)	PUNCT
admet-189	444	12	pillars	pillar	NOUN
admet-189	444	13	to	to	PART
admet-189	444	14	fabricate	fabricate	VERB
admet-189	444	15	microelectrodes	microelectrode	NOUN
admet-189	444	16	[	[	X
admet-189	444	17	112	112	NUM
admet-189	444	18	]	]	PUNCT
admet-189	444	19	and	and	CCONJ
admet-189	444	20	successfully	successfully	ADV
admet-189	444	21	created	create	VERB
admet-189	444	22	a	a	DET
admet-189	444	23	neural	neural	ADJ
admet-189	444	24	interface	interface	NOUN
admet-189	444	25	prototype	prototype	NOUN
admet-189	444	26	device	device	NOUN
admet-189	444	27	using	use	VERB
admet-189	444	28	cnt	cnt	PROPN
admet-189	444	29	microarrays	microarray	NOUN
admet-189	444	30	containing	contain	VERB
admet-189	444	31	cnt	cnt	PROPN
admet-189	444	32	microelectrodes	microelectrode	NOUN
admet-189	444	33	.	.	PUNCT
admet-189	445	1	the	the	DET
admet-189	445	2	neurons	neuron	NOUN
admet-189	445	3	could	could	AUX
admet-189	445	4	grow	grow	VERB
admet-189	445	5	and	and	CCONJ
admet-189	445	6	differentiate	differentiate	VERB
admet-189	445	7	on	on	ADP
admet-189	445	8	the	the	DET
admet-189	445	9	interface	interface	NOUN
admet-189	445	10	as	as	ADV
admet-189	445	11	well	well	ADV
admet-189	445	12	as	as	ADP
admet-189	445	13	could	could	AUX
admet-189	445	14	be	be	AUX
admet-189	445	15	repeatedly	repeatedly	ADV
admet-189	445	16	excited	excite	VERB
admet-189	445	17	.	.	PUNCT
admet-189	446	1	the	the	DET
admet-189	446	2	important	important	ADJ
admet-189	446	3	parameters	parameter	NOUN
admet-189	446	4	that	that	PRON
admet-189	446	5	were	be	AUX
admet-189	446	6	identified	identify	VERB
admet-189	446	7	included	include	VERB
admet-189	446	8	the	the	DET
admet-189	446	9	high	high	ADJ
admet-189	446	10	charge	charge	NOUN
admet-189	446	11	injection	injection	NOUN
admet-189	446	12	limit	limit	NOUN
admet-189	446	13	offered	offer	VERB
admet-189	446	14	by	by	ADP
admet-189	446	15	these	these	DET
admet-189	446	16	functionalized	functionalize	VERB
admet-189	446	17	hydrophilic	hydrophilic	ADJ
admet-189	446	18	cnt	cnt	PROPN
admet-189	446	19	microelectrodes	microelectrode	VERB
admet-189	446	20	without	without	ADP
admet-189	446	21	faradic	faradic	ADJ
admet-189	446	22	reactions	reaction	NOUN
admet-189	446	23	[	[	X
admet-189	446	24	114	114	NUM
admet-189	446	25	]	]	PUNCT
admet-189	446	26	.	.	PUNCT
admet-189	447	1	this	this	PRON
admet-189	447	2	ensured	ensure	VERB
admet-189	447	3	the	the	DET
admet-189	447	4	efficient	efficient	ADJ
admet-189	447	5	and	and	CCONJ
admet-189	447	6	safe	safe	ADJ
admet-189	447	7	electrical	electrical	ADJ
admet-189	447	8	stimulation	stimulation	NOUN
admet-189	447	9	of	of	ADP
admet-189	447	10	neurons	neuron	NOUN
admet-189	447	11	and	and	CCONJ
admet-189	447	12	had	have	VERB
admet-189	447	13	several	several	ADJ
admet-189	447	14	uses	use	NOUN
admet-189	447	15	in	in	ADP
admet-189	447	16	diagnosis	diagnosis	NOUN
admet-189	447	17	and	and	CCONJ
admet-189	447	18	therapy	therapy	NOUN
admet-189	447	19	of	of	ADP
admet-189	447	20	neurological	neurological	ADJ
admet-189	447	21	diseases	disease	NOUN
admet-189	447	22	like	like	ADP
admet-189	447	23	pd	pd	X
admet-189	448	1	[	[	X
admet-189	448	2	114	114	NUM
admet-189	448	3	]	]	PUNCT
admet-189	448	4	.	.	PUNCT
admet-189	449	1	conducting	conduct	VERB
admet-189	449	2	polymersanother	polymersanother	ADJ
admet-189	449	3	group	group	NOUN
admet-189	449	4	of	of	ADP
admet-189	449	5	innovations	innovation	NOUN
admet-189	449	6	in	in	ADP
admet-189	449	7	this	this	DET
admet-189	449	8	field	field	NOUN
admet-189	449	9	is	be	AUX
admet-189	449	10	the	the	DET
admet-189	449	11	development	development	NOUN
admet-189	449	12	of	of	ADP
admet-189	449	13	coatings	coating	NOUN
admet-189	449	14	on	on	ADP
admet-189	449	15	neural	neural	ADJ
admet-189	449	16	prosthetic	prosthetic	ADJ
admet-189	449	17	implants	implant	NOUN
admet-189	449	18	using	use	VERB
admet-189	449	19	conductive	conductive	ADJ
admet-189	449	20	polymers	polymer	NOUN
admet-189	449	21	containing	contain	VERB
admet-189	449	22	alternating	alternate	VERB
admet-189	449	23	double	double	ADJ
admet-189	449	24	and	and	CCONJ
admet-189	449	25	single	single	ADJ
admet-189	449	26	bonds	bond	NOUN
admet-189	449	27	in	in	ADP
admet-189	449	28	their	their	PRON
admet-189	449	29	structure	structure	NOUN
admet-189	449	30	[	[	X
admet-189	449	31	115	115	NUM
admet-189	449	32	]	]	PUNCT
admet-189	449	33	.	.	PUNCT
admet-189	450	1	polypyrrole	polypyrrole	PROPN
admet-189	450	2	(	(	PUNCT
admet-189	450	3	ppy	ppy	PROPN
admet-189	450	4	)	)	PUNCT
admet-189	450	5	,	,	PUNCT
admet-189	450	6	poly(ethylene	poly(ethylene	ADJ
admet-189	450	7	dioxythiophene	dioxythiophene	NOUN
admet-189	450	8	)	)	PUNCT
admet-189	450	9	(	(	PUNCT
admet-189	450	10	pedot	pedot	ADV
admet-189	450	11	)	)	PUNCT
admet-189	450	12	,	,	PUNCT
admet-189	450	13	polyaniline	polyaniline	NOUN
admet-189	450	14	and	and	CCONJ
admet-189	450	15	polyterthiophene	polyterthiophene	NOUN
admet-189	450	16	are	be	AUX
admet-189	450	17	common	common	ADJ
admet-189	450	18	examples	example	NOUN
admet-189	450	19	of	of	ADP
admet-189	450	20	such	such	ADJ
admet-189	450	21	polymers	polymer	NOUN
admet-189	450	22	[	[	X
admet-189	450	23	115	115	NUM
admet-189	450	24	]	]	PUNCT
admet-189	450	25	.	.	PUNCT
admet-189	451	1	george	george	PROPN
admet-189	451	2	et	et	PROPN
admet-189	451	3	al	al	PROPN
admet-189	451	4	.	.	PROPN
admet-189	451	5	found	find	VERB
admet-189	451	6	polypyrrole	polypyrrole	NOUN
admet-189	451	7	implants	implant	NOUN
admet-189	451	8	used	use	VERB
admet-189	451	9	in	in	ADP
admet-189	451	10	microfabricated	microfabricated	ADJ
admet-189	451	11	neural	neural	ADJ
admet-189	451	12	prosthetics	prosthetic	NOUN
admet-189	451	13	allowed	allow	VERB
admet-189	451	14	the	the	DET
admet-189	451	15	growth	growth	NOUN
admet-189	451	16	of	of	ADP
admet-189	451	17	neural	neural	ADJ
admet-189	451	18	connections	connection	NOUN
admet-189	451	19	on	on	ADP
admet-189	451	20	all	all	DET
admet-189	451	21	surfaces	surface	NOUN
admet-189	451	22	[	[	X
admet-189	451	23	116	116	NUM
admet-189	451	24	]	]	PUNCT
admet-189	451	25	.	.	PUNCT
admet-189	452	1	however	however	ADV
admet-189	452	2	,	,	PUNCT
admet-189	452	3	these	these	DET
admet-189	452	4	implants	implant	NOUN
admet-189	452	5	showed	show	VERB
admet-189	452	6	tissue	tissue	NOUN
admet-189	452	7	reactions	reaction	NOUN
admet-189	452	8	in	in	ADP
admet-189	452	9	the	the	DET
admet-189	452	10	brain	brain	NOUN
admet-189	452	11	in	in	ADP
admet-189	452	12	the	the	DET
admet-189	452	13	form	form	NOUN
admet-189	452	14	of	of	ADP
admet-189	452	15	gliosis	gliosis	NOUN
admet-189	453	1	[	[	X
admet-189	453	2	116	116	X
admet-189	453	3	]	]	PUNCT
admet-189	453	4	which	which	PRON
admet-189	453	5	was	be	AUX
admet-189	453	6	one	one	NUM
admet-189	453	7	of	of	ADP
admet-189	453	8	the	the	DET
admet-189	453	9	major	major	ADJ
admet-189	453	10	causes	cause	NOUN
admet-189	453	11	of	of	ADP
admet-189	453	12	failure	failure	NOUN
admet-189	453	13	of	of	ADP
admet-189	453	14	these	these	DET
admet-189	453	15	electrode	electrode	NOUN
admet-189	453	16	arrays	array	NOUN
admet-189	453	17	within	within	ADP
admet-189	453	18	a	a	DET
admet-189	453	19	few	few	ADJ
admet-189	453	20	weeks	week	NOUN
admet-189	453	21	after	after	ADP
admet-189	453	22	implantation	implantation	NOUN
admet-189	453	23	[	[	X
admet-189	453	24	117	117	NUM
admet-189	453	25	]	]	PUNCT
admet-189	453	26	.	.	PUNCT
admet-189	454	1	to	to	PART
admet-189	454	2	tackle	tackle	VERB
admet-189	454	3	this	this	DET
admet-189	454	4	problem	problem	NOUN
admet-189	454	5	,	,	PUNCT
admet-189	454	6	wadhwa	wadhwa	PROPN
admet-189	454	7	et	et	PROPN
admet-189	454	8	al	al	PROPN
admet-189	454	9	.	.	PROPN
admet-189	454	10	proposed	propose	VERB
admet-189	454	11	ppy	ppy	PROPN
admet-189	454	12	based	base	VERB
admet-189	454	13	coatings	coating	NOUN
admet-189	454	14	on	on	ADP
admet-189	454	15	the	the	DET
admet-189	454	16	electrodes	electrode	NOUN
admet-189	454	17	r.	r.	PROPN
admet-189	454	18	banerjee	banerjee	PROPN
admet-189	454	19	et	et	PROPN
admet-189	454	20	al	al	PROPN
admet-189	454	21	.	.	PROPN
admet-189	454	22	admet	admet	PROPN
admet-189	454	23	&	&	CCONJ
admet-189	454	24	dmpk	dmpk	PROPN
admet-189	454	25	3(3	3(3	NUM
admet-189	454	26	)	)	PUNCT
admet-189	454	27	(	(	PUNCT
admet-189	454	28	2015	2015	NUM
admet-189	454	29	)	)	PUNCT
admet-189	454	30	155	155	NUM
admet-189	454	31	-	-	SYM
admet-189	454	32	181	181	NUM
admet-189	454	33	172	172	NUM
admet-189	454	34	with	with	ADP
admet-189	454	35	electrically	electrically	ADV
admet-189	454	36	controlled	control	VERB
admet-189	454	37	local	local	ADJ
admet-189	454	38	delivery	delivery	NOUN
admet-189	454	39	of	of	ADP
admet-189	454	40	dexamethasone	dexamethasone	NOUN
admet-189	454	41	(	(	PUNCT
admet-189	454	42	dex	dex	NOUN
admet-189	454	43	)	)	PUNCT
admet-189	454	44	,	,	PUNCT
admet-189	454	45	a	a	DET
admet-189	454	46	drug	drug	NOUN
admet-189	454	47	which	which	PRON
admet-189	454	48	is	be	AUX
admet-189	454	49	known	know	VERB
admet-189	454	50	to	to	PART
admet-189	454	51	reduce	reduce	VERB
admet-189	454	52	tissue	tissue	NOUN
admet-189	454	53	reactions	reaction	NOUN
admet-189	454	54	and	and	CCONJ
admet-189	454	55	gliosis	gliosis	NOUN
admet-189	455	1	[	[	X
admet-189	455	2	117	117	NUM
admet-189	455	3	]	]	PUNCT
admet-189	455	4	.	.	PUNCT
admet-189	456	1	micromachining	micromachine	VERB
admet-189	456	2	and	and	CCONJ
admet-189	456	3	one	one	NUM
admet-189	456	4	step	step	NOUN
admet-189	456	5	electropolymerization	electropolymerization	NOUN
admet-189	456	6	was	be	AUX
admet-189	456	7	used	use	VERB
admet-189	456	8	for	for	ADP
admet-189	456	9	the	the	DET
admet-189	456	10	deposition	deposition	NOUN
admet-189	456	11	of	of	ADP
admet-189	456	12	a	a	DET
admet-189	456	13	thin	thin	ADJ
admet-189	456	14	film	film	NOUN
admet-189	456	15	(	(	PUNCT
admet-189	456	16	several	several	ADJ
admet-189	456	17	nm	nm	NOUN
admet-189	456	18	)	)	PUNCT
admet-189	456	19	of	of	ADP
admet-189	456	20	ppy	ppy	PROPN
admet-189	456	21	and	and	CCONJ
admet-189	456	22	the	the	DET
admet-189	456	23	drug	drug	NOUN
admet-189	456	24	on	on	ADP
admet-189	456	25	the	the	DET
admet-189	456	26	gold	gold	NOUN
admet-189	456	27	coated	coat	VERB
admet-189	456	28	electrode	electrode	NOUN
admet-189	456	29	surface	surface	NOUN
admet-189	456	30	for	for	ADP
admet-189	456	31	the	the	DET
admet-189	456	32	fabrication	fabrication	NOUN
admet-189	456	33	of	of	ADP
admet-189	456	34	this	this	DET
admet-189	456	35	smart	smart	ADJ
admet-189	456	36	electrode	electrode	NOUN
admet-189	456	37	capable	capable	ADJ
admet-189	456	38	of	of	ADP
admet-189	456	39	responsiveness	responsiveness	NOUN
admet-189	456	40	to	to	ADP
admet-189	456	41	electrical	electrical	ADJ
admet-189	456	42	stimulus	stimulus	NOUN
admet-189	457	1	[	[	X
admet-189	457	2	117	117	NUM
admet-189	457	3	]	]	PUNCT
admet-189	457	4	.	.	PUNCT
admet-189	458	1	the	the	DET
admet-189	458	2	added	add	VERB
admet-189	458	3	advantage	advantage	NOUN
admet-189	458	4	of	of	ADP
admet-189	458	5	use	use	NOUN
admet-189	458	6	of	of	ADP
admet-189	458	7	polypyrrole	polypyrrole	NOUN
admet-189	458	8	in	in	ADP
admet-189	458	9	such	such	ADJ
admet-189	458	10	smart	smart	ADJ
admet-189	458	11	platforms	platform	NOUN
admet-189	458	12	is	be	AUX
admet-189	458	13	the	the	DET
admet-189	458	14	fact	fact	NOUN
admet-189	458	15	that	that	SCONJ
admet-189	458	16	redox	redox	ADJ
admet-189	458	17	reactions	reaction	NOUN
admet-189	458	18	cause	cause	VERB
admet-189	458	19	the	the	DET
admet-189	458	20	charging	charging	NOUN
admet-189	458	21	and	and	CCONJ
admet-189	458	22	discharging	discharging	NOUN
admet-189	458	23	of	of	ADP
admet-189	458	24	these	these	DET
admet-189	458	25	polymers	polymer	NOUN
admet-189	458	26	and	and	CCONJ
admet-189	458	27	can	can	AUX
admet-189	458	28	lead	lead	VERB
admet-189	458	29	to	to	ADP
admet-189	458	30	the	the	DET
admet-189	458	31	movement	movement	NOUN
admet-189	458	32	of	of	ADP
admet-189	458	33	hydrated	hydrated	ADJ
admet-189	458	34	ions	ion	NOUN
admet-189	458	35	,	,	PUNCT
admet-189	458	36	drugs	drug	NOUN
admet-189	458	37	and	and	CCONJ
admet-189	458	38	growth	growth	NOUN
admet-189	458	39	factors	factor	NOUN
admet-189	458	40	in	in	ADP
admet-189	458	41	and	and	CCONJ
admet-189	458	42	out	out	ADP
admet-189	458	43	of	of	ADP
admet-189	458	44	the	the	DET
admet-189	458	45	bulk	bulk	NOUN
admet-189	458	46	of	of	ADP
admet-189	458	47	the	the	DET
admet-189	458	48	polymer	polymer	NOUN
admet-189	458	49	[	[	X
admet-189	458	50	117	117	NUM
admet-189	458	51	]	]	PUNCT
admet-189	458	52	.	.	PUNCT
admet-189	459	1	the	the	DET
admet-189	459	2	drug	drug	NOUN
admet-189	459	3	loaded	load	VERB
admet-189	459	4	into	into	ADP
admet-189	459	5	the	the	DET
admet-189	459	6	electrode	electrode	NOUN
admet-189	459	7	was	be	AUX
admet-189	459	8	released	release	VERB
admet-189	459	9	in	in	ADP
admet-189	459	10	the	the	DET
admet-189	459	11	buffer	buffer	NOUN
admet-189	459	12	solution	solution	NOUN
admet-189	459	13	in	in	ADP
admet-189	459	14	the	the	DET
admet-189	459	15	presence	presence	NOUN
admet-189	459	16	of	of	ADP
admet-189	459	17	an	an	DET
admet-189	459	18	electrical	electrical	ADJ
admet-189	459	19	trigger	trigger	NOUN
admet-189	459	20	that	that	PRON
admet-189	459	21	was	be	AUX
admet-189	459	22	applied	apply	VERB
admet-189	459	23	through	through	ADP
admet-189	459	24	cyclic	cyclic	ADJ
admet-189	459	25	voltammetry	voltammetry	NOUN
admet-189	459	26	[	[	X
admet-189	459	27	117	117	NUM
admet-189	459	28	]	]	PUNCT
admet-189	459	29	.	.	PUNCT
admet-189	460	1	conductive	conductive	ADJ
admet-189	460	2	polymer	polymer	NOUN
admet-189	460	3	hydrogelsthe	hydrogelsthe	NOUN
admet-189	460	4	increased	increase	VERB
admet-189	460	5	biocompatibility	biocompatibility	NOUN
admet-189	460	6	of	of	ADP
admet-189	460	7	these	these	DET
admet-189	460	8	drug	drug	NOUN
admet-189	460	9	-	-	PUNCT
admet-189	460	10	eluting	elute	VERB
admet-189	460	11	coatings	coating	NOUN
admet-189	460	12	on	on	ADP
admet-189	460	13	smart	smart	ADJ
admet-189	460	14	microelectrodes	microelectrode	NOUN
admet-189	460	15	led	lead	VERB
admet-189	460	16	to	to	ADP
admet-189	460	17	research	research	NOUN
admet-189	460	18	towards	towards	ADP
admet-189	460	19	increasing	increase	VERB
admet-189	460	20	the	the	DET
admet-189	460	21	drug	drug	NOUN
admet-189	460	22	loading	loading	NOUN
admet-189	460	23	and	and	CCONJ
admet-189	460	24	stimulus	stimulus	ADJ
admet-189	460	25	responsiveness	responsiveness	NOUN
admet-189	460	26	of	of	ADP
admet-189	460	27	the	the	DET
admet-189	460	28	electrodes	electrode	NOUN
admet-189	460	29	.	.	PUNCT
admet-189	461	1	this	this	DET
admet-189	461	2	lead	lead	NOUN
admet-189	461	3	to	to	ADP
admet-189	461	4	conducting	conduct	VERB
admet-189	461	5	polymers	polymer	NOUN
admet-189	461	6	being	be	AUX
admet-189	461	7	incorporated	incorporate	VERB
admet-189	461	8	inside	inside	ADP
admet-189	461	9	hydrogel	hydrogel	NOUN
admet-189	461	10	-	-	PUNCT
admet-189	461	11	support	support	NOUN
admet-189	461	12	matrices	matrix	NOUN
admet-189	461	13	,	,	PUNCT
admet-189	461	14	a	a	DET
admet-189	461	15	class	class	NOUN
admet-189	461	16	of	of	ADP
admet-189	461	17	materials	material	NOUN
admet-189	461	18	called	call	VERB
admet-189	461	19	conductive	conductive	ADJ
admet-189	461	20	polymer	polymer	NOUN
admet-189	461	21	hydrogels	hydrogel	NOUN
admet-189	461	22	(	(	PUNCT
admet-189	461	23	cph	cph	NOUN
admet-189	461	24	)	)	PUNCT
admet-189	462	1	[	[	X
admet-189	462	2	118	118	NUM
admet-189	462	3	]	]	PUNCT
admet-189	462	4	.	.	PUNCT
admet-189	463	1	such	such	DET
admet-189	463	2	a	a	DET
admet-189	463	3	matrix	matrix	NOUN
admet-189	463	4	can	can	AUX
admet-189	463	5	allow	allow	VERB
admet-189	463	6	more	more	ADJ
admet-189	463	7	drug	drug	NOUN
admet-189	463	8	incorporation	incorporation	NOUN
admet-189	463	9	along	along	ADP
admet-189	463	10	with	with	ADP
admet-189	463	11	faster	fast	ADJ
admet-189	463	12	release	release	NOUN
admet-189	463	13	[	[	X
admet-189	463	14	117	117	NUM
admet-189	463	15	]	]	PUNCT
admet-189	463	16	.	.	PUNCT
admet-189	464	1	these	these	DET
admet-189	464	2	properties	property	NOUN
admet-189	464	3	can	can	AUX
admet-189	464	4	be	be	AUX
admet-189	464	5	further	far	ADV
admet-189	464	6	enhanced	enhance	VERB
admet-189	464	7	through	through	ADP
admet-189	464	8	the	the	DET
admet-189	464	9	increase	increase	NOUN
admet-189	464	10	in	in	ADP
admet-189	464	11	surface	surface	NOUN
admet-189	464	12	area	area	NOUN
admet-189	464	13	by	by	ADP
admet-189	464	14	creating	create	VERB
admet-189	464	15	nano	nano	NOUN
admet-189	464	16	-	-	PUNCT
admet-189	464	17	fibrous	fibrous	ADJ
admet-189	464	18	morphology	morphology	NOUN
admet-189	464	19	employing	employ	VERB
admet-189	464	20	nano	nano	NOUN
admet-189	464	21	-	-	PUNCT
admet-189	464	22	templating	template	VERB
admet-189	464	23	techniques	technique	NOUN
admet-189	464	24	[	[	X
admet-189	464	25	117	117	NUM
admet-189	464	26	]	]	PUNCT
admet-189	464	27	.	.	PUNCT
admet-189	465	1	such	such	ADJ
admet-189	465	2	devices	device	NOUN
admet-189	465	3	can	can	AUX
admet-189	465	4	serve	serve	VERB
admet-189	465	5	as	as	ADP
admet-189	465	6	mechanical	mechanical	ADJ
admet-189	465	7	buffers	buffer	NOUN
admet-189	465	8	in	in	ADP
admet-189	465	9	the	the	DET
admet-189	465	10	interface	interface	NOUN
admet-189	465	11	between	between	ADP
admet-189	465	12	the	the	DET
admet-189	465	13	hard	hard	ADJ
admet-189	465	14	electrodes	electrode	NOUN
admet-189	465	15	and	and	CCONJ
admet-189	465	16	the	the	DET
admet-189	465	17	soft	soft	ADJ
admet-189	465	18	brain	brain	NOUN
admet-189	465	19	tissue	tissue	NOUN
admet-189	465	20	improving	improve	VERB
admet-189	465	21	contact	contact	NOUN
admet-189	465	22	with	with	ADP
admet-189	465	23	viable	viable	ADJ
admet-189	465	24	neurons	neuron	NOUN
admet-189	465	25	while	while	SCONJ
admet-189	465	26	increasing	increase	VERB
admet-189	465	27	biocompatibility	biocompatibility	NOUN
admet-189	465	28	and	and	CCONJ
admet-189	465	29	limiting	limit	VERB
admet-189	465	30	protein	protein	NOUN
admet-189	465	31	adsorption	adsorption	NOUN
admet-189	465	32	to	to	ADP
admet-189	465	33	the	the	DET
admet-189	465	34	neural	neural	ADJ
admet-189	465	35	prosthetic	prosthetic	ADJ
admet-189	465	36	electrodes	electrode	NOUN
admet-189	465	37	[	[	X
admet-189	465	38	117,118	117,118	NUM
admet-189	465	39	]	]	PUNCT
admet-189	465	40	.	.	PUNCT
admet-189	466	1	according	accord	VERB
admet-189	466	2	to	to	ADP
admet-189	466	3	a	a	DET
admet-189	466	4	study	study	NOUN
admet-189	466	5	by	by	ADP
admet-189	466	6	nguyen	nguyen	PROPN
admet-189	466	7	et	et	PROPN
admet-189	466	8	al	al	PROPN
admet-189	466	9	.	.	PROPN
admet-189	466	10	,	,	PUNCT
admet-189	466	11	the	the	DET
admet-189	466	12	incorporation	incorporation	NOUN
admet-189	466	13	of	of	ADP
admet-189	466	14	a	a	DET
admet-189	466	15	mechanically	mechanically	ADV
admet-189	466	16	-	-	PUNCT
admet-189	466	17	compliant	compliant	ADJ
admet-189	466	18	implant	implant	NOUN
admet-189	466	19	in	in	ADP
admet-189	466	20	the	the	DET
admet-189	466	21	brain	brain	NOUN
admet-189	466	22	parenchyma	parenchyma	NOUN
admet-189	466	23	can	can	AUX
admet-189	466	24	reduce	reduce	VERB
admet-189	466	25	the	the	DET
admet-189	466	26	inflammatory	inflammatory	ADJ
admet-189	466	27	response	response	NOUN
admet-189	466	28	in	in	ADP
admet-189	466	29	comparison	comparison	NOUN
admet-189	466	30	to	to	PART
admet-189	466	31	stiffer	stiffer	VERB
admet-189	466	32	systems	system	NOUN
admet-189	466	33	[	[	X
admet-189	466	34	119	119	NUM
admet-189	466	35	]	]	PUNCT
admet-189	466	36	.	.	PUNCT
admet-189	467	1	thus	thus	ADV
admet-189	467	2	,	,	PUNCT
admet-189	467	3	cph	cph	PROPN
admet-189	467	4	coated	coat	VERB
admet-189	467	5	electrodes	electrode	NOUN
admet-189	467	6	are	be	AUX
admet-189	467	7	biocompatible	biocompatible	ADJ
admet-189	467	8	by	by	ADP
admet-189	467	9	themselves	themselves	PRON
admet-189	467	10	and	and	CCONJ
admet-189	467	11	can	can	AUX
admet-189	467	12	be	be	AUX
admet-189	467	13	additionally	additionally	ADV
admet-189	467	14	used	use	VERB
admet-189	467	15	to	to	PART
admet-189	467	16	deliver	deliver	VERB
admet-189	467	17	drugs	drug	NOUN
admet-189	467	18	and	and	CCONJ
admet-189	467	19	growth	growth	NOUN
admet-189	467	20	factors	factor	NOUN
admet-189	467	21	locally	locally	ADV
admet-189	467	22	.	.	PUNCT
admet-189	467	23	.	.	PUNCT
admet-189	468	1	kim	kim	PROPN
admet-189	468	2	et	et	PROPN
admet-189	468	3	al	al	PROPN
admet-189	468	4	.	.	PROPN
admet-189	468	5	used	use	VERB
admet-189	468	6	ppy	ppy	PROPN
admet-189	468	7	grown	grow	VERB
admet-189	468	8	electrochemically	electrochemically	ADV
admet-189	468	9	on	on	ADP
admet-189	468	10	the	the	DET
admet-189	468	11	scaffolds	scaffold	NOUN
admet-189	468	12	made	make	VERB
admet-189	468	13	of	of	ADP
admet-189	468	14	hydrogels	hydrogel	NOUN
admet-189	468	15	followed	follow	VERB
admet-189	468	16	by	by	ADP
admet-189	468	17	deposition	deposition	NOUN
admet-189	468	18	on	on	ADP
admet-189	468	19	the	the	DET
admet-189	468	20	surface	surface	NOUN
admet-189	468	21	of	of	ADP
admet-189	468	22	neural	neural	ADJ
admet-189	468	23	prosthetic	prosthetic	ADJ
admet-189	468	24	devices	device	NOUN
admet-189	468	25	[	[	X
admet-189	468	26	120	120	NUM
admet-189	468	27	]	]	PUNCT
admet-189	468	28	.	.	PUNCT
admet-189	469	1	the	the	DET
admet-189	469	2	coating	coating	NOUN
admet-189	469	3	was	be	AUX
admet-189	469	4	found	find	VERB
admet-189	469	5	to	to	PART
admet-189	469	6	reduce	reduce	VERB
admet-189	469	7	impedance	impedance	NOUN
admet-189	469	8	and	and	CCONJ
admet-189	469	9	improve	improve	VERB
admet-189	469	10	electrical	electrical	ADJ
admet-189	469	11	properties	property	NOUN
admet-189	469	12	of	of	ADP
admet-189	469	13	the	the	DET
admet-189	469	14	electrodes	electrode	NOUN
admet-189	469	15	[	[	X
admet-189	469	16	120	120	NUM
admet-189	469	17	]	]	PUNCT
admet-189	469	18	.	.	PUNCT
admet-189	470	1	however	however	ADV
admet-189	470	2	,	,	PUNCT
admet-189	470	3	hydrogels	hydrogel	NOUN
admet-189	470	4	have	have	VERB
admet-189	470	5	the	the	DET
admet-189	470	6	inherent	inherent	ADJ
admet-189	470	7	property	property	NOUN
admet-189	470	8	of	of	ADP
admet-189	470	9	a	a	DET
admet-189	470	10	high	high	ADJ
admet-189	470	11	swelling	swell	VERB
admet-189	470	12	ratio	ratio	NOUN
admet-189	470	13	and	and	CCONJ
admet-189	470	14	its	its	PRON
admet-189	470	15	swelling	swelling	NOUN
admet-189	470	16	in	in	ADP
admet-189	470	17	situ	situ	NOUN
admet-189	470	18	can	can	AUX
admet-189	470	19	lead	lead	VERB
admet-189	470	20	to	to	PART
admet-189	470	21	increase	increase	VERB
admet-189	470	22	in	in	ADP
admet-189	470	23	the	the	DET
admet-189	470	24	distance	distance	NOUN
admet-189	470	25	from	from	ADP
admet-189	470	26	the	the	DET
admet-189	470	27	brain	brain	NOUN
admet-189	470	28	surface	surface	NOUN
admet-189	470	29	and	and	CCONJ
admet-189	470	30	the	the	DET
admet-189	470	31	microelectrode	microelectrode	NOUN
admet-189	470	32	reducing	reduce	VERB
admet-189	470	33	the	the	DET
admet-189	470	34	efficiency	efficiency	NOUN
admet-189	470	35	of	of	ADP
admet-189	470	36	deep	deep	ADJ
admet-189	470	37	brain	brain	NOUN
admet-189	470	38	stimulation	stimulation	NOUN
admet-189	470	39	.	.	PUNCT
admet-189	471	1	to	to	PART
admet-189	471	2	deal	deal	VERB
admet-189	471	3	with	with	ADP
admet-189	471	4	this	this	DET
admet-189	471	5	problem	problem	NOUN
admet-189	471	6	,	,	PUNCT
admet-189	471	7	bio	bio	ADJ
admet-189	471	8	-	-	PUNCT
admet-189	471	9	inspired	inspire	VERB
admet-189	471	10	hybrid	hybrid	ADJ
admet-189	471	11	microelectrodes	microelectrode	NOUN
admet-189	471	12	were	be	AUX
admet-189	471	13	fabricated	fabricate	VERB
admet-189	471	14	by	by	ADP
admet-189	471	15	de	de	X
admet-189	471	16	faveri	faveri	PROPN
admet-189	471	17	et	et	PROPN
admet-189	471	18	al	al	PROPN
admet-189	471	19	.	.	PROPN
admet-189	472	1	in	in	ADP
admet-189	472	2	which	which	PRON
admet-189	472	3	they	they	PRON
admet-189	472	4	used	use	VERB
admet-189	472	5	highly	highly	ADV
admet-189	472	6	biocompatible	biocompatible	ADJ
admet-189	472	7	fibrin	fibrin	NOUN
admet-189	472	8	coatings	coating	NOUN
admet-189	473	1	[	[	X
admet-189	473	2	121	121	NUM
admet-189	473	3	]	]	PUNCT
admet-189	473	4	.	.	PUNCT
admet-189	474	1	the	the	DET
admet-189	474	2	fibrin	fibrin	NOUN
admet-189	474	3	coatings	coating	NOUN
admet-189	474	4	reduced	reduce	VERB
admet-189	474	5	host	host	NOUN
admet-189	474	6	reaction	reaction	NOUN
admet-189	474	7	within	within	ADP
admet-189	474	8	7	7	NUM
admet-189	474	9	days	day	NOUN
admet-189	474	10	of	of	ADP
admet-189	474	11	implantation	implantation	NOUN
admet-189	474	12	and	and	CCONJ
admet-189	474	13	allowed	allow	VERB
admet-189	474	14	growth	growth	NOUN
admet-189	474	15	of	of	ADP
admet-189	474	16	both	both	DET
admet-189	474	17	neurons	neuron	NOUN
admet-189	474	18	and	and	CCONJ
admet-189	474	19	astrocytes	astrocyte	NOUN
admet-189	474	20	[	[	X
admet-189	474	21	121	121	NUM
admet-189	474	22	]	]	PUNCT
admet-189	474	23	.	.	PUNCT
admet-189	475	1	but	but	CCONJ
admet-189	475	2	most	most	ADV
admet-189	475	3	importantly	importantly	ADV
admet-189	475	4	,	,	PUNCT
admet-189	475	5	the	the	DET
admet-189	475	6	fibrin	fibrin	NOUN
admet-189	475	7	coating	coating	NOUN
admet-189	475	8	displayed	display	VERB
admet-189	475	9	a	a	DET
admet-189	475	10	smaller	small	ADJ
admet-189	475	11	swelling	swelling	NOUN
admet-189	475	12	than	than	ADP
admet-189	475	13	other	other	ADJ
admet-189	475	14	types	type	NOUN
admet-189	475	15	of	of	ADP
admet-189	475	16	hydrogels	hydrogel	NOUN
admet-189	475	17	and	and	CCONJ
admet-189	475	18	allowed	allow	VERB
admet-189	475	19	the	the	DET
admet-189	475	20	control	control	NOUN
admet-189	475	21	of	of	ADP
admet-189	475	22	coating	coat	VERB
admet-189	475	23	thickness	thickness	NOUN
admet-189	476	1	[	[	X
admet-189	476	2	121	121	NUM
admet-189	476	3	]	]	PUNCT
admet-189	476	4	.	.	PUNCT
admet-189	477	1	thus	thus	ADV
admet-189	477	2	,	,	PUNCT
admet-189	477	3	the	the	DET
admet-189	477	4	problem	problem	NOUN
admet-189	477	5	of	of	ADP
admet-189	477	6	hydrogel	hydrogel	NOUN
admet-189	477	7	swelling	swell	VERB
admet-189	477	8	could	could	AUX
admet-189	477	9	be	be	AUX
admet-189	477	10	tackled	tackle	VERB
admet-189	477	11	with	with	ADP
admet-189	477	12	suitable	suitable	ADJ
admet-189	477	13	bio	bio	ADJ
admet-189	477	14	-	-	PUNCT
admet-189	477	15	inspired	inspire	VERB
admet-189	477	16	coatings	coating	NOUN
admet-189	477	17	.	.	PUNCT
admet-189	478	1	thus	thus	ADV
admet-189	478	2	,	,	PUNCT
admet-189	478	3	nanotechnology	nanotechnology	NOUN
admet-189	478	4	is	be	AUX
admet-189	478	5	being	be	AUX
admet-189	478	6	increasingly	increasingly	ADV
admet-189	478	7	employed	employ	VERB
admet-189	478	8	for	for	ADP
admet-189	478	9	the	the	DET
admet-189	478	10	development	development	NOUN
admet-189	478	11	of	of	ADP
admet-189	478	12	better	well	ADJ
admet-189	478	13	neural	neural	ADJ
admet-189	478	14	prosthetic	prosthetic	ADJ
admet-189	478	15	electrodes	electrode	NOUN
admet-189	478	16	for	for	ADP
admet-189	478	17	deep	deep	ADJ
admet-189	478	18	brain	brain	NOUN
admet-189	478	19	stimulation	stimulation	NOUN
admet-189	478	20	.	.	PUNCT
admet-189	479	1	further	further	ADJ
admet-189	479	2	advances	advance	NOUN
admet-189	479	3	in	in	ADP
admet-189	479	4	the	the	DET
admet-189	479	5	fabrication	fabrication	NOUN
admet-189	479	6	and	and	CCONJ
admet-189	479	7	stimulus	stimulus	ADJ
admet-189	479	8	responsiveness	responsiveness	NOUN
admet-189	479	9	of	of	ADP
admet-189	479	10	these	these	DET
admet-189	479	11	technologies	technology	NOUN
admet-189	479	12	can	can	AUX
admet-189	479	13	help	help	VERB
admet-189	479	14	incorporate	incorporate	VERB
admet-189	479	15	dbs	dbs	NOUN
admet-189	479	16	as	as	ADP
admet-189	479	17	a	a	DET
admet-189	479	18	safer	safe	ADJ
admet-189	479	19	treatment	treatment	NOUN
admet-189	479	20	modality	modality	NOUN
admet-189	479	21	in	in	ADP
admet-189	479	22	the	the	DET
admet-189	479	23	management	management	NOUN
admet-189	479	24	of	of	ADP
admet-189	479	25	parkinson	parkinson	NOUN
admet-189	479	26	’s	’s	PART
admet-189	479	27	disease	disease	NOUN
admet-189	479	28	.	.	PUNCT
admet-189	480	1	nanotechnology	nanotechnology	NOUN
admet-189	480	2	in	in	ADP
admet-189	480	3	neurosurgery	neurosurgery	NOUN
admet-189	480	4	after	after	ADP
admet-189	480	5	the	the	DET
admet-189	480	6	introduction	introduction	NOUN
admet-189	480	7	of	of	ADP
admet-189	480	8	levodopa	levodopa	NOUN
admet-189	480	9	half	half	DET
admet-189	480	10	a	a	DET
admet-189	480	11	century	century	NOUN
admet-189	480	12	ago	ago	ADV
admet-189	480	13	,	,	PUNCT
admet-189	480	14	neurosurgery	neurosurgery	NOUN
admet-189	480	15	was	be	AUX
admet-189	480	16	abandoned	abandon	VERB
admet-189	480	17	for	for	ADP
admet-189	480	18	the	the	DET
admet-189	480	19	management	management	NOUN
admet-189	480	20	of	of	ADP
admet-189	480	21	parkinson	parkinson	NOUN
admet-189	480	22	’s	’s	PART
admet-189	480	23	disease	disease	NOUN
admet-189	480	24	.	.	PUNCT
admet-189	481	1	however	however	ADV
admet-189	481	2	,	,	PUNCT
admet-189	481	3	the	the	DET
admet-189	481	4	past	past	ADJ
admet-189	481	5	decade	decade	NOUN
admet-189	481	6	saw	see	VERB
admet-189	481	7	the	the	DET
admet-189	481	8	resurgence	resurgence	NOUN
admet-189	481	9	of	of	ADP
admet-189	481	10	the	the	DET
admet-189	481	11	surgical	surgical	ADJ
admet-189	481	12	treatment	treatment	NOUN
admet-189	481	13	of	of	ADP
admet-189	481	14	pd	pd	PROPN
admet-189	481	15	using	use	VERB
admet-189	481	16	pallidotomy	pallidotomy	NOUN
admet-189	481	17	and	and	CCONJ
admet-189	481	18	thalamotomy	thalamotomy	NOUN
admet-189	481	19	[	[	X
admet-189	481	20	103	103	NUM
admet-189	481	21	]	]	PUNCT
admet-189	481	22	.	.	PUNCT
admet-189	482	1	this	this	PRON
admet-189	482	2	was	be	AUX
admet-189	482	3	due	due	ADJ
admet-189	482	4	to	to	ADP
admet-189	482	5	the	the	DET
admet-189	482	6	inherent	inherent	ADJ
admet-189	482	7	drawbacks	drawback	NOUN
admet-189	482	8	of	of	ADP
admet-189	482	9	drug	drug	NOUN
admet-189	482	10	therapy	therapy	NOUN
admet-189	482	11	in	in	ADP
admet-189	482	12	which	which	PRON
admet-189	482	13	the	the	DET
admet-189	482	14	prolonged	prolonged	ADJ
admet-189	482	15	administration	administration	NOUN
admet-189	482	16	of	of	ADP
admet-189	482	17	drugs	drug	NOUN
admet-189	482	18	lead	lead	VERB
admet-189	482	19	to	to	ADP
admet-189	482	20	drug	drug	NOUN
admet-189	482	21	-	-	PUNCT
admet-189	482	22	induced	induce	VERB
admet-189	482	23	motor	motor	NOUN
admet-189	482	24	symptoms	symptom	NOUN
admet-189	482	25	[	[	X
admet-189	482	26	103	103	NUM
admet-189	482	27	]	]	PUNCT
admet-189	482	28	.	.	PUNCT
admet-189	483	1	with	with	ADP
admet-189	483	2	the	the	DET
admet-189	483	3	advent	advent	NOUN
admet-189	483	4	of	of	ADP
admet-189	483	5	the	the	DET
admet-189	483	6	age	age	NOUN
admet-189	483	7	of	of	ADP
admet-189	483	8	nanotechnology	nanotechnology	NOUN
admet-189	483	9	,	,	PUNCT
admet-189	483	10	there	there	PRON
admet-189	483	11	have	have	AUX
admet-189	483	12	been	be	AUX
admet-189	483	13	great	great	ADJ
admet-189	483	14	strides	stride	NOUN
admet-189	483	15	in	in	ADP
admet-189	483	16	the	the	DET
admet-189	483	17	precision	precision	NOUN
admet-189	483	18	in	in	ADP
admet-189	483	19	neurosurgery	neurosurgery	NOUN
admet-189	483	20	.	.	PUNCT
admet-189	484	1	laser	laser	NOUN
admet-189	484	2	axotomyone	axotomyone	ADJ
admet-189	484	3	of	of	ADP
admet-189	484	4	the	the	DET
admet-189	484	5	most	most	ADV
admet-189	484	6	intriguing	intriguing	ADJ
admet-189	484	7	techniques	technique	NOUN
admet-189	484	8	in	in	ADP
admet-189	484	9	the	the	DET
admet-189	484	10	field	field	NOUN
admet-189	484	11	of	of	ADP
admet-189	484	12	nanotechnology	nanotechnology	NOUN
admet-189	484	13	is	be	AUX
admet-189	484	14	the	the	DET
admet-189	484	15	use	use	NOUN
admet-189	484	16	of	of	ADP
admet-189	484	17	admet	admet	PROPN
admet-189	484	18	&	&	CCONJ
admet-189	484	19	dmpk	dmpk	PROPN
admet-189	484	20	3(3	3(3	NUM
admet-189	484	21	)	)	PUNCT
admet-189	484	22	(	(	PUNCT
admet-189	484	23	2015	2015	NUM
admet-189	484	24	)	)	PUNCT
admet-189	484	25	155	155	NUM
admet-189	484	26	-	-	SYM
admet-189	484	27	181	181	NUM
admet-189	484	28	nanotechnology	nanotechnology	NOUN
admet-189	484	29	platforms	platform	NOUN
admet-189	484	30	in	in	ADP
admet-189	484	31	parkinson	parkinson	NOUN
admet-189	484	32	’s	’s	PART
admet-189	484	33	disease	disease	NOUN
admet-189	484	34	doi	doi	NOUN
admet-189	484	35	:	:	PUNCT
admet-189	484	36	10.5599	10.5599	NUM
admet-189	484	37	/	/	SYM
admet-189	484	38	admet.3.3.189	admet.3.3.189	ADP
admet-189	484	39	173	173	NUM
admet-189	484	40	femtosecond	femtosecond	NOUN
admet-189	484	41	laser	laser	NOUN
admet-189	484	42	axotomy	axotomy	ADV
admet-189	484	43	which	which	PRON
admet-189	484	44	is	be	AUX
admet-189	484	45	being	be	AUX
admet-189	484	46	developed	develop	VERB
admet-189	484	47	as	as	ADP
admet-189	484	48	a	a	DET
admet-189	484	49	neurosurgical	neurosurgical	ADJ
admet-189	484	50	tool	tool	NOUN
admet-189	484	51	with	with	ADP
admet-189	484	52	100	100	NUM
admet-189	484	53	%	%	NOUN
admet-189	484	54	efficiency	efficiency	NOUN
admet-189	484	55	,	,	PUNCT
admet-189	484	56	precision	precision	NOUN
admet-189	484	57	in	in	ADP
admet-189	484	58	the	the	DET
admet-189	484	59	range	range	NOUN
admet-189	484	60	of	of	ADP
admet-189	484	61	nanometers	nanometer	NOUN
admet-189	484	62	and	and	CCONJ
admet-189	484	63	high	high	ADJ
admet-189	484	64	speed	speed	NOUN
admet-189	484	65	.	.	PUNCT
admet-189	485	1	the	the	DET
admet-189	485	2	most	most	ADV
admet-189	485	3	widely	widely	ADV
admet-189	485	4	cited	cite	VERB
admet-189	485	5	example	example	NOUN
admet-189	485	6	of	of	ADP
admet-189	485	7	this	this	DET
admet-189	485	8	precise	precise	ADJ
admet-189	485	9	technique	technique	NOUN
admet-189	485	10	is	be	AUX
admet-189	485	11	by	by	ADP
admet-189	485	12	yanik	yanik	PROPN
admet-189	485	13	et	et	PROPN
admet-189	485	14	al	al	PROPN
admet-189	485	15	.	.	PROPN
admet-189	486	1	(	(	PUNCT
admet-189	486	2	2011	2011	NUM
admet-189	486	3	)	)	PUNCT
admet-189	486	4	where	where	SCONJ
admet-189	486	5	femtosecond	femtosecond	NOUN
admet-189	486	6	laser	laser	NOUN
admet-189	486	7	axotomy	axotomy	ADV
admet-189	486	8	was	be	AUX
admet-189	486	9	used	use	VERB
admet-189	486	10	to	to	PART
admet-189	486	11	cut	cut	VERB
admet-189	486	12	single	single	ADJ
admet-189	486	13	axons	axon	NOUN
admet-189	486	14	inside	inside	ADP
admet-189	486	15	the	the	DET
admet-189	486	16	roundworm	roundworm	NOUN
admet-189	486	17	c.	c.	NOUN
admet-189	486	18	elegans	elegan	NOUN
admet-189	486	19	by	by	ADP
admet-189	486	20	using	use	VERB
admet-189	486	21	focused	focus	VERB
admet-189	486	22	nano	nano	NOUN
admet-189	486	23	-	-	PUNCT
admet-189	486	24	scale	scale	NOUN
admet-189	486	25	near	near	ADP
admet-189	486	26	-	-	PUNCT
admet-189	486	27	infrared	infrared	ADJ
admet-189	486	28	laser	laser	NOUN
admet-189	486	29	pulse	pulse	NOUN
admet-189	486	30	energies	energy	NOUN
admet-189	486	31	(	(	PUNCT
admet-189	486	32	10–40	10–40	NUM
admet-189	486	33	nanojoules	nanojoule	NOUN
admet-189	486	34	)	)	PUNCT
admet-189	486	35	of	of	ADP
admet-189	486	36	200	200	NUM
admet-189	486	37	-	-	PUNCT
admet-189	486	38	femtoseconds	femtosecond	NOUN
admet-189	486	39	[	[	X
admet-189	486	40	122	122	NUM
admet-189	486	41	]	]	PUNCT
admet-189	486	42	.	.	PUNCT
admet-189	487	1	this	this	PRON
admet-189	487	2	resulted	result	VERB
admet-189	487	3	in	in	ADP
admet-189	487	4	the	the	DET
admet-189	487	5	vaporization	vaporization	NOUN
admet-189	487	6	of	of	ADP
admet-189	487	7	femtolitres	femtolitre	NOUN
admet-189	487	8	of	of	ADP
admet-189	487	9	axon	axon	NOUN
admet-189	487	10	volumes	volume	NOUN
admet-189	487	11	and	and	CCONJ
admet-189	487	12	subsequent	subsequent	ADJ
admet-189	487	13	cutting	cutting	NOUN
admet-189	487	14	of	of	ADP
admet-189	487	15	the	the	DET
admet-189	487	16	axon	axon	NOUN
admet-189	487	17	processes	process	VERB
admet-189	487	18	[	[	X
admet-189	487	19	122	122	NUM
admet-189	487	20	]	]	PUNCT
admet-189	487	21	.	.	PUNCT
admet-189	488	1	besides	besides	SCONJ
admet-189	488	2	,	,	PUNCT
admet-189	488	3	the	the	DET
admet-189	488	4	technique	technique	NOUN
admet-189	488	5	was	be	AUX
admet-189	488	6	robust	robust	ADJ
admet-189	488	7	allowing	allow	VERB
admet-189	488	8	the	the	DET
admet-189	488	9	use	use	NOUN
admet-189	488	10	of	of	ADP
admet-189	488	11	confocal	confocal	ADJ
admet-189	488	12	fluorescence	fluorescence	NOUN
admet-189	488	13	imaging	imaging	NOUN
admet-189	488	14	and	and	CCONJ
admet-189	488	15	laser	laser	NOUN
admet-189	488	16	scanning	scanning	NOUN
admet-189	488	17	brightfield	brightfield	NOUN
admet-189	488	18	for	for	ADP
admet-189	488	19	real	real	ADJ
admet-189	488	20	-	-	PUNCT
admet-189	488	21	time	time	NOUN
admet-189	488	22	imaging	imaging	NOUN
admet-189	488	23	from	from	ADP
admet-189	488	24	the	the	DET
admet-189	488	25	first	first	ADJ
admet-189	488	26	incision	incision	NOUN
admet-189	488	27	to	to	ADP
admet-189	488	28	the	the	DET
admet-189	488	29	end	end	NOUN
admet-189	488	30	[	[	X
admet-189	488	31	122].the	122].the	DET
admet-189	488	32	surgical	surgical	ADJ
admet-189	488	33	technique	technique	NOUN
admet-189	488	34	has	have	AUX
admet-189	488	35	improved	improve	VERB
admet-189	488	36	understanding	understanding	NOUN
admet-189	488	37	of	of	ADP
admet-189	488	38	a	a	DET
admet-189	488	39	number	number	NOUN
admet-189	488	40	of	of	ADP
admet-189	488	41	processes	process	NOUN
admet-189	488	42	in	in	ADP
admet-189	488	43	nerve	nerve	NOUN
admet-189	488	44	cell	cell	NOUN
admet-189	488	45	injury	injury	NOUN
admet-189	489	1	[	[	X
admet-189	489	2	123	123	NUM
admet-189	489	3	]	]	PUNCT
admet-189	489	4	and	and	CCONJ
admet-189	489	5	has	have	AUX
admet-189	489	6	also	also	ADV
admet-189	489	7	paved	pave	VERB
admet-189	489	8	way	way	NOUN
admet-189	489	9	for	for	ADP
admet-189	489	10	an	an	DET
admet-189	489	11	all	all	DET
admet-189	489	12	new	new	ADJ
admet-189	489	13	concept	concept	NOUN
admet-189	489	14	of	of	ADP
admet-189	489	15	nanomanipulation	nanomanipulation	NOUN
admet-189	489	16	.	.	PUNCT
admet-189	490	1	vibrating	vibrate	VERB
admet-189	490	2	micropipetteanother	micropipetteanother	CCONJ
admet-189	490	3	widely	widely	ADV
admet-189	490	4	popular	popular	ADJ
admet-189	490	5	technology	technology	NOUN
admet-189	490	6	is	be	AUX
admet-189	490	7	the	the	DET
admet-189	490	8	use	use	NOUN
admet-189	490	9	of	of	ADP
admet-189	490	10	a	a	DET
admet-189	490	11	rapidly	rapidly	ADV
admet-189	490	12	vibrating	vibrate	VERB
admet-189	490	13	(	(	PUNCT
admet-189	490	14	100	100	NUM
admet-189	490	15	hz	hz	ADJ
admet-189	490	16	)	)	PUNCT
admet-189	490	17	micropipette	micropipette	NOUN
admet-189	490	18	(	(	PUNCT
admet-189	490	19	tip	tip	NOUN
admet-189	490	20	diameter	diameter	NOUN
admet-189	490	21	in	in	ADP
admet-189	490	22	nanometers	nanometer	NOUN
admet-189	490	23	)	)	PUNCT
admet-189	490	24	which	which	PRON
admet-189	490	25	when	when	SCONJ
admet-189	490	26	dragged	drag	VERB
admet-189	490	27	across	across	ADP
admet-189	490	28	the	the	DET
admet-189	490	29	dendrite	dendrite	NOUN
admet-189	490	30	of	of	ADP
admet-189	490	31	a	a	DET
admet-189	490	32	selected	select	VERB
admet-189	490	33	neuron	neuron	NOUN
admet-189	490	34	can	can	AUX
admet-189	490	35	help	help	VERB
admet-189	490	36	in	in	ADP
admet-189	490	37	dissection	dissection	NOUN
admet-189	490	38	of	of	ADP
admet-189	490	39	apical	apical	ADJ
admet-189	490	40	dendrites	dendrite	NOUN
admet-189	490	41	[	[	X
admet-189	490	42	124	124	NUM
admet-189	490	43	]	]	PUNCT
admet-189	490	44	.	.	PUNCT
admet-189	491	1	this	this	PRON
admet-189	491	2	provided	provide	VERB
admet-189	491	3	a	a	DET
admet-189	491	4	simple	simple	ADJ
admet-189	491	5	system	system	NOUN
admet-189	491	6	for	for	ADP
admet-189	491	7	cutting	cut	VERB
admet-189	491	8	dendrites	dendrite	NOUN
admet-189	491	9	from	from	ADP
admet-189	491	10	single	single	ADJ
admet-189	491	11	neurons	neuron	NOUN
admet-189	491	12	without	without	ADP
admet-189	491	13	damaging	damage	VERB
admet-189	491	14	the	the	DET
admet-189	491	15	cell	cell	NOUN
admet-189	492	1	[	[	X
admet-189	492	2	124	124	NUM
admet-189	492	3	]	]	PUNCT
admet-189	492	4	.	.	PUNCT
admet-189	493	1	nanotweezersthe	nanotweezersthe	PRON
admet-189	493	2	word	word	NOUN
admet-189	493	3	nanotweezers	nanotweezer	NOUN
admet-189	493	4	is	be	AUX
admet-189	493	5	being	be	AUX
admet-189	493	6	widely	widely	ADV
admet-189	493	7	used	use	VERB
admet-189	493	8	with	with	ADP
admet-189	493	9	different	different	ADJ
admet-189	493	10	meanings	meaning	NOUN
admet-189	493	11	but	but	CCONJ
admet-189	493	12	with	with	ADP
admet-189	493	13	the	the	DET
admet-189	493	14	same	same	ADJ
admet-189	493	15	purpose	purpose	NOUN
admet-189	493	16	of	of	ADP
admet-189	493	17	precise	precise	ADJ
admet-189	493	18	manipulation	manipulation	NOUN
admet-189	493	19	in	in	ADP
admet-189	493	20	the	the	DET
admet-189	493	21	nanometer	nanometer	NOUN
admet-189	493	22	range	range	NOUN
admet-189	493	23	.	.	PUNCT
admet-189	494	1	the	the	DET
admet-189	494	2	nanotweezers	nanotweezer	NOUN
admet-189	494	3	may	may	AUX
admet-189	494	4	be	be	AUX
admet-189	494	5	of	of	ADP
admet-189	494	6	nanoscale	nanoscale	ADJ
admet-189	494	7	electromechanical	electromechanical	ADJ
admet-189	494	8	systems	system	NOUN
admet-189	494	9	based	base	VERB
admet-189	494	10	on	on	ADP
admet-189	494	11	carbon	carbon	NOUN
admet-189	494	12	nanotubes	nanotube	NOUN
admet-189	494	13	fabricated	fabricate	VERB
admet-189	494	14	on	on	ADP
admet-189	494	15	pulled	pull	VERB
admet-189	494	16	glass	glass	NOUN
admet-189	494	17	micropipettes	micropipette	NOUN
admet-189	494	18	as	as	SCONJ
admet-189	494	19	described	describe	VERB
admet-189	494	20	by	by	ADP
admet-189	494	21	kim	kim	PROPN
admet-189	494	22	et	et	PROPN
admet-189	494	23	al	al	PROPN
admet-189	494	24	.	.	PUNCT
admet-189	495	1	[	[	X
admet-189	495	2	120	120	NUM
admet-189	495	3	]	]	PUNCT
admet-189	495	4	.	.	PUNCT
admet-189	496	1	voltages	voltage	NOUN
admet-189	496	2	that	that	PRON
admet-189	496	3	are	be	AUX
admet-189	496	4	applied	apply	VERB
admet-189	496	5	to	to	ADP
admet-189	496	6	these	these	DET
admet-189	496	7	electrodes	electrode	NOUN
admet-189	496	8	could	could	AUX
admet-189	496	9	open	open	VERB
admet-189	496	10	or	or	CCONJ
admet-189	496	11	close	close	VERB
admet-189	496	12	the	the	DET
admet-189	496	13	free	free	ADJ
admet-189	496	14	ends	end	NOUN
admet-189	496	15	of	of	ADP
admet-189	496	16	the	the	DET
admet-189	496	17	nanotubes	nanotube	NOUN
admet-189	496	18	allowing	allow	VERB
admet-189	496	19	grabbing	grabbing	NOUN
admet-189	496	20	and	and	CCONJ
admet-189	496	21	manipulation	manipulation	NOUN
admet-189	496	22	of	of	ADP
admet-189	496	23	submicron	submicron	NOUN
admet-189	496	24	clusters	cluster	NOUN
admet-189	496	25	and	and	CCONJ
admet-189	496	26	nanowires	nanowire	VERB
admet-189	496	27	[	[	X
admet-189	496	28	120	120	NUM
admet-189	496	29	]	]	PUNCT
admet-189	496	30	.	.	PUNCT
admet-189	497	1	the	the	DET
admet-189	497	2	mechanical	mechanical	ADJ
admet-189	497	3	capabilities	capability	NOUN
admet-189	497	4	of	of	ADP
admet-189	497	5	such	such	ADJ
admet-189	497	6	nanotweezers	nanotweezer	NOUN
admet-189	497	7	can	can	AUX
admet-189	497	8	be	be	AUX
admet-189	497	9	put	put	VERB
admet-189	497	10	to	to	PART
admet-189	497	11	use	use	VERB
admet-189	497	12	for	for	ADP
admet-189	497	13	grabbing	grab	VERB
admet-189	497	14	and	and	CCONJ
admet-189	497	15	manipulating	manipulate	VERB
admet-189	497	16	neurons	neuron	NOUN
admet-189	497	17	as	as	ADV
admet-189	497	18	well	well	ADV
admet-189	497	19	.	.	PUNCT
admet-189	498	1	a	a	DET
admet-189	498	2	rather	rather	ADV
admet-189	498	3	higher	high	ADJ
admet-189	498	4	level	level	NOUN
admet-189	498	5	of	of	ADP
admet-189	498	6	precision	precision	NOUN
admet-189	498	7	in	in	ADP
admet-189	498	8	manipulation	manipulation	NOUN
admet-189	498	9	is	be	AUX
admet-189	498	10	by	by	ADP
admet-189	498	11	the	the	DET
admet-189	498	12	use	use	NOUN
admet-189	498	13	photoswitchable	photoswitchable	ADJ
admet-189	498	14	crosslinkers	crosslinker	NOUN
admet-189	498	15	which	which	PRON
admet-189	498	16	in	in	ADP
admet-189	498	17	response	response	NOUN
admet-189	498	18	to	to	ADP
admet-189	498	19	light	light	NOUN
admet-189	498	20	can	can	AUX
admet-189	498	21	manipulate	manipulate	VERB
admet-189	498	22	the	the	DET
admet-189	498	23	normal	normal	ADJ
admet-189	498	24	physiological	physiological	ADJ
admet-189	498	25	signal	signal	NOUN
admet-189	498	26	or	or	CCONJ
admet-189	498	27	induce	induce	VERB
admet-189	498	28	structural	structural	ADJ
admet-189	498	29	changes	change	NOUN
admet-189	498	30	in	in	ADP
admet-189	498	31	peptides	peptide	NOUN
admet-189	498	32	and	and	CCONJ
admet-189	498	33	ion	ion	NOUN
admet-189	498	34	channels	channel	NOUN
admet-189	498	35	allowing	allow	VERB
admet-189	498	36	molecular	molecular	ADJ
admet-189	498	37	level	level	NOUN
admet-189	498	38	manipulation	manipulation	NOUN
admet-189	498	39	of	of	ADP
admet-189	498	40	cells	cell	NOUN
admet-189	498	41	[	[	X
admet-189	498	42	125	125	NUM
admet-189	498	43	]	]	PUNCT
admet-189	498	44	.	.	PUNCT
admet-189	499	1	the	the	DET
admet-189	499	2	use	use	NOUN
admet-189	499	3	of	of	ADP
admet-189	499	4	light	light	NOUN
admet-189	499	5	is	be	AUX
admet-189	499	6	being	be	AUX
admet-189	499	7	increasingly	increasingly	ADV
admet-189	499	8	used	use	VERB
admet-189	499	9	for	for	ADP
admet-189	499	10	the	the	DET
admet-189	499	11	study	study	NOUN
admet-189	499	12	of	of	ADP
admet-189	499	13	disease	disease	NOUN
admet-189	499	14	circuitry	circuitry	NOUN
admet-189	499	15	in	in	ADP
admet-189	499	16	parkinson	parkinson	NOUN
admet-189	499	17	’s	’s	PART
admet-189	499	18	disease	disease	NOUN
admet-189	499	19	especially	especially	ADV
admet-189	499	20	through	through	ADP
admet-189	499	21	optogenetics	optogenetic	NOUN
admet-189	499	22	which	which	PRON
admet-189	499	23	is	be	AUX
admet-189	499	24	a	a	DET
admet-189	499	25	novel	novel	ADJ
admet-189	499	26	technique	technique	NOUN
admet-189	499	27	of	of	ADP
admet-189	499	28	gene	gene	NOUN
admet-189	499	29	delivery	delivery	NOUN
admet-189	499	30	through	through	ADP
admet-189	499	31	encoding	encoding	NOUN
admet-189	499	32	of	of	ADP
admet-189	499	33	proteins	protein	NOUN
admet-189	499	34	capable	capable	ADJ
admet-189	499	35	of	of	ADP
admet-189	499	36	instilling	instill	VERB
admet-189	499	37	light	light	ADJ
admet-189	499	38	sensitivity	sensitivity	NOUN
admet-189	499	39	to	to	ADP
admet-189	499	40	neurons	neuron	NOUN
admet-189	499	41	[	[	X
admet-189	499	42	126	126	NUM
admet-189	499	43	]	]	PUNCT
admet-189	499	44	.	.	PUNCT
admet-189	500	1	these	these	DET
admet-189	500	2	technologies	technology	NOUN
admet-189	500	3	once	once	ADV
admet-189	500	4	translated	translate	VERB
admet-189	500	5	can	can	AUX
admet-189	500	6	improve	improve	VERB
admet-189	500	7	the	the	DET
admet-189	500	8	precision	precision	NOUN
admet-189	500	9	of	of	ADP
admet-189	500	10	neurosurgery	neurosurgery	NOUN
admet-189	500	11	to	to	ADP
admet-189	500	12	molecular	molecular	ADJ
admet-189	500	13	ranges	range	NOUN
admet-189	500	14	.	.	PUNCT
admet-189	501	1	nanotechnology	nanotechnology	NOUN
admet-189	501	2	and	and	CCONJ
admet-189	501	3	the	the	DET
admet-189	501	4	use	use	NOUN
admet-189	501	5	of	of	ADP
admet-189	501	6	smart	smart	ADJ
admet-189	501	7	nanoparticles	nanoparticle	NOUN
admet-189	501	8	can	can	AUX
admet-189	501	9	greatly	greatly	ADV
admet-189	501	10	improve	improve	VERB
admet-189	501	11	the	the	DET
admet-189	501	12	precision	precision	NOUN
admet-189	501	13	of	of	ADP
admet-189	501	14	such	such	ADJ
admet-189	501	15	surgical	surgical	ADJ
admet-189	501	16	devices	device	NOUN
admet-189	501	17	from	from	ADP
admet-189	501	18	cutting	cut	VERB
admet-189	501	19	neuronal	neuronal	ADJ
admet-189	501	20	processes	process	NOUN
admet-189	501	21	to	to	ADP
admet-189	501	22	modifying	modify	VERB
admet-189	501	23	ion	ion	NOUN
admet-189	501	24	channels	channel	NOUN
admet-189	501	25	using	use	VERB
admet-189	501	26	light	light	NOUN
admet-189	501	27	.	.	PUNCT
admet-189	502	1	as	as	SCONJ
admet-189	502	2	these	these	DET
admet-189	502	3	devices	device	NOUN
admet-189	502	4	are	be	AUX
admet-189	502	5	gradually	gradually	ADV
admet-189	502	6	becoming	become	VERB
admet-189	502	7	popular	popular	ADJ
admet-189	502	8	in	in	ADP
admet-189	502	9	the	the	DET
admet-189	502	10	lab	lab	NOUN
admet-189	502	11	,	,	PUNCT
admet-189	502	12	their	their	PRON
admet-189	502	13	translation	translation	NOUN
admet-189	502	14	to	to	ADP
admet-189	502	15	bedside	bedside	NOUN
admet-189	502	16	is	be	AUX
admet-189	502	17	possible	possible	ADJ
admet-189	502	18	in	in	ADP
admet-189	502	19	the	the	DET
admet-189	502	20	near	near	ADJ
admet-189	502	21	future	future	NOUN
admet-189	502	22	.	.	PUNCT
admet-189	503	1	the	the	DET
admet-189	503	2	essential	essential	ADJ
admet-189	503	3	precision	precision	NOUN
admet-189	503	4	that	that	SCONJ
admet-189	503	5	these	these	DET
admet-189	503	6	nanotechnological	nanotechnological	ADJ
admet-189	503	7	tools	tool	NOUN
admet-189	503	8	add	add	VERB
admet-189	503	9	,	,	PUNCT
admet-189	503	10	can	can	AUX
admet-189	503	11	lead	lead	VERB
admet-189	503	12	to	to	ADP
admet-189	503	13	a	a	DET
admet-189	503	14	safer	safe	ADJ
admet-189	503	15	neurosurgical	neurosurgical	ADJ
admet-189	503	16	option	option	NOUN
admet-189	503	17	for	for	ADP
admet-189	503	18	patients	patient	NOUN
admet-189	503	19	with	with	ADP
admet-189	503	20	pd	pd	PROPN
admet-189	503	21	as	as	ADP
admet-189	503	22	with	with	ADP
admet-189	503	23	many	many	ADJ
admet-189	503	24	other	other	ADJ
admet-189	503	25	neurological	neurological	ADJ
admet-189	503	26	diseases	disease	NOUN
admet-189	503	27	.	.	PUNCT
admet-189	504	1	tissue	tissue	NOUN
admet-189	504	2	engineering	engineering	NOUN
admet-189	504	3	approaches	approach	NOUN
admet-189	504	4	finding	find	VERB
admet-189	504	5	the	the	DET
admet-189	504	6	ideal	ideal	ADJ
admet-189	504	7	platform	platform	NOUN
admet-189	504	8	the	the	DET
admet-189	504	9	dopaminergic	dopaminergic	ADJ
admet-189	504	10	neurons	neuron	NOUN
admet-189	504	11	in	in	ADP
admet-189	504	12	the	the	DET
admet-189	504	13	substantia	substantia	NOUN
admet-189	504	14	nigra	nigra	NOUN
admet-189	504	15	responsible	responsible	ADJ
admet-189	504	16	for	for	ADP
admet-189	504	17	cortical	cortical	ADJ
admet-189	504	18	and	and	CCONJ
admet-189	504	19	thalamic	thalamic	ADJ
admet-189	504	20	regulation	regulation	NOUN
admet-189	504	21	are	be	AUX
admet-189	504	22	lost	lose	VERB
admet-189	504	23	in	in	ADP
admet-189	504	24	pd	pd	NOUN
admet-189	504	25	leading	lead	VERB
admet-189	504	26	to	to	ADP
admet-189	504	27	motor	motor	NOUN
admet-189	504	28	dysfunction	dysfunction	NOUN
admet-189	504	29	(	(	PUNCT
admet-189	504	30	tremor	tremor	NOUN
admet-189	504	31	,	,	PUNCT
admet-189	504	32	rigidity	rigidity	NOUN
admet-189	504	33	,	,	PUNCT
admet-189	504	34	and	and	CCONJ
admet-189	504	35	bradykinesia	bradykinesia	NOUN
admet-189	504	36	)	)	PUNCT
admet-189	504	37	and	and	CCONJ
admet-189	504	38	non	non	ADJ
admet-189	504	39	-	-	ADJ
admet-189	504	40	motor	motor	ADJ
admet-189	504	41	symptoms	symptom	NOUN
admet-189	504	42	(	(	PUNCT
admet-189	504	43	depression	depression	NOUN
admet-189	504	44	,	,	PUNCT
admet-189	504	45	anxiety	anxiety	NOUN
admet-189	504	46	)	)	PUNCT
admet-189	505	1	[	[	X
admet-189	505	2	103	103	NUM
admet-189	505	3	]	]	PUNCT
admet-189	505	4	.	.	PUNCT
admet-189	506	1	the	the	DET
admet-189	506	2	transplantation	transplantation	NOUN
admet-189	506	3	of	of	ADP
admet-189	506	4	fetal	fetal	ADJ
admet-189	506	5	tissue	tissue	NOUN
admet-189	506	6	in	in	ADP
admet-189	506	7	the	the	DET
admet-189	506	8	form	form	NOUN
admet-189	506	9	of	of	ADP
admet-189	506	10	human	human	ADJ
admet-189	506	11	fetal	fetal	ADJ
admet-189	506	12	ventral	ventral	ADJ
admet-189	506	13	mesencephalon	mesencephalon	NOUN
admet-189	506	14	was	be	AUX
admet-189	506	15	one	one	NUM
admet-189	506	16	of	of	ADP
admet-189	506	17	the	the	DET
admet-189	506	18	most	most	ADV
admet-189	506	19	promising	promising	ADJ
admet-189	506	20	treatments	treatment	NOUN
admet-189	506	21	in	in	ADP
admet-189	506	22	the	the	DET
admet-189	506	23	1980s	1980	NOUN
admet-189	506	24	and	and	CCONJ
admet-189	506	25	stimulated	stimulate	VERB
admet-189	506	26	a	a	DET
admet-189	506	27	number	number	NOUN
admet-189	506	28	of	of	ADP
admet-189	506	29	clinical	clinical	ADJ
admet-189	506	30	trials	trial	NOUN
admet-189	506	31	with	with	ADP
admet-189	506	32	varied	varied	ADJ
admet-189	506	33	protocols	protocol	NOUN
admet-189	506	34	and	and	CCONJ
admet-189	506	35	endpoints	endpoint	NOUN
admet-189	506	36	[	[	X
admet-189	506	37	127,128	127,128	NUM
admet-189	506	38	]	]	PUNCT
admet-189	506	39	.	.	PUNCT
admet-189	507	1	there	there	PRON
admet-189	507	2	were	be	VERB
admet-189	507	3	reports	report	NOUN
admet-189	507	4	of	of	ADP
admet-189	507	5	clinical	clinical	ADJ
admet-189	507	6	improvement	improvement	NOUN
admet-189	507	7	and	and	CCONJ
admet-189	507	8	two	two	NUM
admet-189	507	9	decades	decade	NOUN
admet-189	507	10	later	later	ADV
admet-189	507	11	,	,	PUNCT
admet-189	507	12	after	after	ADP
admet-189	507	13	sufficient	sufficient	ADJ
admet-189	507	14	evidence	evidence	NOUN
admet-189	507	15	of	of	ADP
admet-189	507	16	safety	safety	NOUN
admet-189	507	17	and	and	CCONJ
admet-189	507	18	efficacy	efficacy	NOUN
admet-189	507	19	of	of	ADP
admet-189	507	20	these	these	DET
admet-189	507	21	treatments	treatment	NOUN
admet-189	507	22	,	,	PUNCT
admet-189	507	23	the	the	DET
admet-189	507	24	national	national	PROPN
admet-189	507	25	institutes	institutes	PROPN
admet-189	507	26	of	of	ADP
admet-189	507	27	health	health	PROPN
admet-189	507	28	,	,	PUNCT
admet-189	507	29	usa	usa	PROPN
admet-189	507	30	started	start	VERB
admet-189	507	31	two	two	NUM
admet-189	507	32	clinical	clinical	ADJ
admet-189	507	33	trials	trial	NOUN
admet-189	507	34	in	in	ADP
admet-189	507	35	the	the	DET
admet-189	507	36	early	early	ADJ
admet-189	507	37	2000s	2000	NOUN
admet-189	508	1	[	[	X
admet-189	508	2	127	127	NUM
admet-189	508	3	]	]	PUNCT
admet-189	508	4	.	.	PUNCT
admet-189	509	1	the	the	DET
admet-189	509	2	trials	trial	NOUN
admet-189	509	3	found	find	VERB
admet-189	509	4	the	the	DET
admet-189	509	5	therapy	therapy	NOUN
admet-189	509	6	to	to	PART
admet-189	509	7	be	be	AUX
admet-189	509	8	of	of	ADP
admet-189	509	9	little	little	ADJ
admet-189	509	10	benefit	benefit	NOUN
admet-189	509	11	to	to	ADP
admet-189	509	12	patients	patient	NOUN
admet-189	509	13	and	and	CCONJ
admet-189	509	14	caused	cause	VERB
admet-189	509	15	some	some	PRON
admet-189	509	16	of	of	ADP
admet-189	509	17	the	the	DET
admet-189	509	18	patients	patient	NOUN
admet-189	509	19	to	to	PART
admet-189	509	20	become	become	VERB
admet-189	509	21	worse	bad	ADJ
admet-189	509	22	with	with	ADP
admet-189	509	23	symptoms	symptom	NOUN
admet-189	509	24	like	like	ADP
admet-189	509	25	graftinduced	graftinduce	VERB
admet-189	509	26	dyskinesias	dyskinesia	NOUN
admet-189	509	27	(	(	PUNCT
admet-189	509	28	gid	gid	X
admet-189	509	29	)	)	PUNCT
admet-189	510	1	[	[	X
admet-189	510	2	127,129	127,129	NUM
admet-189	510	3	]	]	PUNCT
admet-189	510	4	.	.	PUNCT
admet-189	511	1	however	however	ADV
admet-189	511	2	,	,	PUNCT
admet-189	511	3	a	a	DET
admet-189	511	4	decade	decade	NOUN
admet-189	511	5	later	later	ADV
admet-189	511	6	,	,	PUNCT
admet-189	511	7	the	the	DET
admet-189	511	8	debate	debate	NOUN
admet-189	511	9	is	be	AUX
admet-189	511	10	still	still	ADV
admet-189	511	11	on	on	ADP
admet-189	511	12	regarding	regard	VERB
admet-189	511	13	the	the	DET
admet-189	511	14	efficiency	efficiency	NOUN
admet-189	511	15	of	of	ADP
admet-189	511	16	stem	stem	NOUN
admet-189	511	17	-	-	PUNCT
admet-189	511	18	cell	cell	NOUN
admet-189	511	19	grafting	grafting	NOUN
admet-189	511	20	[	[	X
admet-189	511	21	128,129	128,129	NUM
admet-189	511	22	]	]	PUNCT
admet-189	511	23	.	.	PUNCT
admet-189	512	1	besides	besides	SCONJ
admet-189	512	2	the	the	DET
admet-189	512	3	concerns	concern	NOUN
admet-189	512	4	in	in	ADP
admet-189	512	5	the	the	DET
admet-189	512	6	clinical	clinical	ADJ
admet-189	512	7	-	-	PUNCT
admet-189	512	8	trial	trial	NOUN
admet-189	512	9	design	design	NOUN
admet-189	512	10	and	and	CCONJ
admet-189	512	11	ethical	ethical	ADJ
admet-189	512	12	issues	issue	NOUN
admet-189	512	13	,	,	PUNCT
admet-189	512	14	the	the	DET
admet-189	512	15	r.	r.	PROPN
admet-189	512	16	banerjee	banerjee	PROPN
admet-189	512	17	et	et	PROPN
admet-189	512	18	al	al	PROPN
admet-189	512	19	.	.	PROPN
admet-189	512	20	admet	admet	PROPN
admet-189	512	21	&	&	CCONJ
admet-189	512	22	dmpk	dmpk	PROPN
admet-189	512	23	3(3	3(3	NUM
admet-189	512	24	)	)	PUNCT
admet-189	512	25	(	(	PUNCT
admet-189	512	26	2015	2015	NUM
admet-189	512	27	)	)	PUNCT
admet-189	512	28	155	155	NUM
admet-189	512	29	-	-	SYM
admet-189	512	30	181	181	NUM
admet-189	512	31	174	174	NUM
admet-189	512	32	technology	technology	NOUN
admet-189	512	33	needed	need	VERB
admet-189	512	34	to	to	PART
admet-189	512	35	be	be	AUX
admet-189	512	36	safe	safe	ADJ
admet-189	512	37	[	[	X
admet-189	512	38	127,128	127,128	NUM
admet-189	512	39	]	]	PUNCT
admet-189	512	40	.	.	PUNCT
admet-189	513	1	these	these	DET
admet-189	513	2	concerns	concern	NOUN
admet-189	513	3	are	be	AUX
admet-189	513	4	more	more	ADV
admet-189	513	5	pronounced	pronounced	ADJ
admet-189	513	6	with	with	ADP
admet-189	513	7	embryonic	embryonic	ADJ
admet-189	513	8	stem	stem	NOUN
admet-189	513	9	cells	cell	NOUN
admet-189	513	10	(	(	PUNCT
admet-189	513	11	escs	esc	NOUN
admet-189	513	12	)	)	PUNCT
admet-189	513	13	because	because	SCONJ
admet-189	513	14	of	of	ADP
admet-189	513	15	their	their	PRON
admet-189	513	16	ability	ability	NOUN
admet-189	513	17	to	to	PART
admet-189	513	18	differentiate	differentiate	VERB
admet-189	513	19	into	into	ADP
admet-189	513	20	a	a	DET
admet-189	513	21	number	number	NOUN
admet-189	513	22	of	of	ADP
admet-189	513	23	cell	cell	NOUN
admet-189	513	24	types	type	NOUN
admet-189	513	25	[	[	X
admet-189	513	26	127	127	NUM
admet-189	513	27	]	]	PUNCT
admet-189	513	28	.	.	PUNCT
admet-189	514	1	a	a	DET
admet-189	514	2	potential	potential	ADJ
admet-189	514	3	solution	solution	NOUN
admet-189	514	4	is	be	AUX
admet-189	514	5	the	the	DET
admet-189	514	6	use	use	NOUN
admet-189	514	7	of	of	ADP
admet-189	514	8	patient	patient	ADJ
admet-189	514	9	derived	derive	VERB
admet-189	514	10	cells	cell	NOUN
admet-189	514	11	and	and	CCONJ
admet-189	514	12	then	then	ADV
admet-189	514	13	induced	induce	VERB
admet-189	514	14	pluripotent	pluripotent	ADJ
admet-189	514	15	stem	stem	NOUN
admet-189	514	16	cells	cell	NOUN
admet-189	514	17	(	(	PUNCT
admet-189	514	18	ipscs	ipsc	NOUN
admet-189	514	19	)	)	PUNCT
admet-189	515	1	[	[	X
admet-189	515	2	127	127	NUM
admet-189	515	3	]	]	PUNCT
admet-189	515	4	.	.	PUNCT
admet-189	516	1	however	however	ADV
admet-189	516	2	,	,	PUNCT
admet-189	516	3	the	the	DET
admet-189	516	4	concern	concern	NOUN
admet-189	516	5	still	still	ADV
admet-189	516	6	lies	lie	VERB
admet-189	516	7	in	in	ADP
admet-189	516	8	the	the	DET
admet-189	516	9	fact	fact	NOUN
admet-189	516	10	that	that	SCONJ
admet-189	516	11	the	the	DET
admet-189	516	12	patient	patient	NOUN
admet-189	516	13	’s	’s	PART
admet-189	516	14	own	own	ADJ
admet-189	516	15	cells	cell	NOUN
admet-189	516	16	may	may	AUX
admet-189	516	17	be	be	AUX
admet-189	516	18	susceptible	susceptible	ADJ
admet-189	516	19	to	to	ADP
admet-189	516	20	the	the	DET
admet-189	516	21	pd	pd	PROPN
admet-189	516	22	pathology	pathology	NOUN
admet-189	516	23	[	[	X
admet-189	516	24	127	127	NUM
admet-189	516	25	]	]	PUNCT
admet-189	516	26	.	.	PUNCT
admet-189	517	1	thus	thus	ADV
admet-189	517	2	,	,	PUNCT
admet-189	517	3	it	it	PRON
admet-189	517	4	is	be	AUX
admet-189	517	5	the	the	DET
admet-189	517	6	trade	trade	NOUN
admet-189	517	7	-	-	PUNCT
admet-189	517	8	off	off	NOUN
admet-189	517	9	between	between	ADP
admet-189	517	10	optimal	optimal	ADJ
admet-189	517	11	ability	ability	NOUN
admet-189	517	12	to	to	PART
admet-189	517	13	proliferate	proliferate	VERB
admet-189	517	14	while	while	SCONJ
admet-189	517	15	dodging	dodge	VERB
admet-189	517	16	the	the	DET
admet-189	517	17	pathogenesis	pathogenesis	NOUN
admet-189	517	18	of	of	ADP
admet-189	517	19	pd	pd	PROPN
admet-189	517	20	that	that	PRON
admet-189	517	21	forms	form	VERB
admet-189	517	22	the	the	DET
admet-189	517	23	basis	basis	NOUN
admet-189	517	24	of	of	ADP
admet-189	517	25	development	development	NOUN
admet-189	517	26	of	of	ADP
admet-189	517	27	a	a	DET
admet-189	517	28	safe	safe	ADJ
admet-189	517	29	treatment	treatment	NOUN
admet-189	517	30	for	for	ADP
admet-189	517	31	pd	pd	PROPN
admet-189	517	32	.	.	PUNCT
admet-189	518	1	direct	direct	ADJ
admet-189	518	2	infusion	infusion	NOUN
admet-189	518	3	of	of	ADP
admet-189	518	4	growth	growth	NOUN
admet-189	518	5	factors	factor	NOUN
admet-189	518	6	like	like	ADP
admet-189	518	7	glial	glial	ADJ
admet-189	518	8	cell	cell	NOUN
admet-189	518	9	–	–	PUNCT
admet-189	518	10	derived	derive	VERB
admet-189	518	11	neurotrophic	neurotrophic	ADJ
admet-189	518	12	factor	factor	NOUN
admet-189	518	13	(	(	PUNCT
admet-189	518	14	gdnf	gdnf	PROPN
admet-189	518	15	)	)	PUNCT
admet-189	518	16	to	to	ADP
admet-189	518	17	the	the	DET
admet-189	518	18	putamen	putaman	NOUN
admet-189	518	19	in	in	ADP
admet-189	518	20	patients	patient	NOUN
admet-189	518	21	with	with	ADP
admet-189	518	22	pd	pd	PROPN
admet-189	518	23	has	have	AUX
admet-189	518	24	been	be	AUX
admet-189	518	25	found	find	VERB
admet-189	518	26	to	to	PART
admet-189	518	27	be	be	AUX
admet-189	518	28	favorable	favorable	ADJ
admet-189	518	29	and	and	CCONJ
admet-189	518	30	are	be	AUX
admet-189	518	31	being	be	AUX
admet-189	518	32	seen	see	VERB
admet-189	518	33	as	as	ADP
admet-189	518	34	prospective	prospective	ADJ
admet-189	518	35	agents	agent	NOUN
admet-189	518	36	for	for	ADP
admet-189	518	37	neuroprotection	neuroprotection	NOUN
admet-189	518	38	[	[	X
admet-189	518	39	103	103	NUM
admet-189	518	40	]	]	PUNCT
admet-189	518	41	.	.	PUNCT
admet-189	519	1	however	however	ADV
admet-189	519	2	,	,	PUNCT
admet-189	519	3	these	these	DET
admet-189	519	4	approaches	approach	NOUN
admet-189	519	5	are	be	AUX
admet-189	519	6	still	still	ADV
admet-189	519	7	to	to	PART
admet-189	519	8	be	be	AUX
admet-189	519	9	verified	verify	VERB
admet-189	519	10	as	as	SCONJ
admet-189	519	11	clinical	clinical	ADJ
admet-189	519	12	trials	trial	NOUN
admet-189	519	13	reflect	reflect	VERB
admet-189	519	14	conflicting	conflicting	ADJ
admet-189	519	15	evidence	evidence	NOUN
admet-189	519	16	[	[	X
admet-189	519	17	103	103	NUM
admet-189	519	18	]	]	SYM
admet-189	519	19	.	.	PUNCT
admet-189	520	1	tissue	tissue	NOUN
admet-189	520	2	engineering	engineering	NOUN
admet-189	520	3	tries	try	VERB
admet-189	520	4	to	to	PART
admet-189	520	5	address	address	VERB
admet-189	520	6	these	these	DET
admet-189	520	7	issues	issue	NOUN
admet-189	520	8	using	use	VERB
admet-189	520	9	stem	stem	NOUN
admet-189	520	10	cells	cell	NOUN
admet-189	520	11	and	and	CCONJ
admet-189	520	12	growth	growth	NOUN
admet-189	520	13	factors	factor	NOUN
admet-189	520	14	in	in	ADP
admet-189	520	15	suitable	suitable	ADJ
admet-189	520	16	scaffolds	scaffold	NOUN
admet-189	520	17	for	for	ADP
admet-189	520	18	the	the	DET
admet-189	520	19	controlled	control	VERB
admet-189	520	20	regeneration	regeneration	NOUN
admet-189	520	21	of	of	ADP
admet-189	520	22	various	various	ADJ
admet-189	520	23	tissues	tissue	NOUN
admet-189	520	24	.	.	PUNCT
admet-189	521	1	it	it	PRON
admet-189	521	2	is	be	AUX
admet-189	521	3	being	be	AUX
admet-189	521	4	increasingly	increasingly	ADV
admet-189	521	5	used	use	VERB
admet-189	521	6	for	for	ADP
admet-189	521	7	neural	neural	ADJ
admet-189	521	8	stem	stem	NOUN
admet-189	521	9	cell	cell	NOUN
admet-189	521	10	engineering	engineering	NOUN
admet-189	521	11	for	for	ADP
admet-189	521	12	parkinson	parkinson	NOUN
admet-189	521	13	’s	’s	PART
admet-189	521	14	disease	disease	NOUN
admet-189	521	15	.	.	PUNCT
admet-189	522	1	nanoparticles	nanoparticle	NOUN
admet-189	522	2	for	for	ADP
admet-189	522	3	delivery	delivery	NOUN
admet-189	522	4	of	of	ADP
admet-189	522	5	versatile	versatile	ADJ
admet-189	522	6	payloads	payload	NOUN
admet-189	522	7	:	:	PUNCT
admet-189	522	8	one	one	NUM
admet-189	522	9	of	of	ADP
admet-189	522	10	the	the	DET
admet-189	522	11	approaches	approach	NOUN
admet-189	522	12	in	in	ADP
admet-189	522	13	tissue	tissue	NOUN
admet-189	522	14	engineering	engineering	NOUN
admet-189	522	15	for	for	ADP
admet-189	522	16	pd	pd	PROPN
admet-189	522	17	is	be	AUX
admet-189	522	18	the	the	DET
admet-189	522	19	use	use	NOUN
admet-189	522	20	of	of	ADP
admet-189	522	21	small	small	ADJ
admet-189	522	22	molecules	molecule	NOUN
admet-189	522	23	as	as	ADP
admet-189	522	24	triggers	trigger	NOUN
admet-189	522	25	to	to	PART
admet-189	522	26	allow	allow	VERB
admet-189	522	27	the	the	DET
admet-189	522	28	differentiation	differentiation	NOUN
admet-189	522	29	of	of	ADP
admet-189	522	30	stem	stem	NOUN
admet-189	522	31	cells	cell	NOUN
admet-189	522	32	into	into	ADP
admet-189	522	33	the	the	DET
admet-189	522	34	neurons	neuron	NOUN
admet-189	522	35	.	.	PUNCT
admet-189	523	1	santos	santos	PROPN
admet-189	523	2	et	et	PROPN
admet-189	523	3	al	al	PROPN
admet-189	523	4	.	.	PROPN
admet-189	523	5	used	use	VERB
admet-189	523	6	retinoic	retinoic	NOUN
admet-189	523	7	acid	acid	NOUN
admet-189	523	8	-	-	PUNCT
admet-189	523	9	loaded	load	VERB
admet-189	523	10	polymeric	polymeric	ADJ
admet-189	523	11	nanoparticles	nanoparticle	NOUN
admet-189	523	12	to	to	PART
admet-189	523	13	induce	induce	VERB
admet-189	523	14	such	such	ADJ
admet-189	523	15	differentiation	differentiation	NOUN
admet-189	523	16	in	in	ADP
admet-189	523	17	subventricular	subventricular	ADJ
admet-189	523	18	zone	zone	NOUN
admet-189	523	19	neural	neural	ADJ
admet-189	523	20	stem	stem	NOUN
admet-189	523	21	cells	cell	NOUN
admet-189	523	22	[	[	X
admet-189	523	23	130	130	NUM
admet-189	523	24	]	]	PUNCT
admet-189	523	25	.	.	PUNCT
admet-189	524	1	the	the	DET
admet-189	524	2	nanoparticles	nanoparticle	NOUN
admet-189	524	3	leveraged	leverage	VERB
admet-189	524	4	the	the	DET
admet-189	524	5	electrostatic	electrostatic	ADJ
admet-189	524	6	interaction	interaction	NOUN
admet-189	524	7	of	of	ADP
admet-189	524	8	polyethylenimine	polyethylenimine	NOUN
admet-189	524	9	(	(	PUNCT
admet-189	524	10	polycation	polycation	NOUN
admet-189	524	11	)	)	PUNCT
admet-189	524	12	with	with	ADP
admet-189	524	13	retinoic	retinoic	ADJ
admet-189	524	14	acid	acid	PROPN
admet-189	524	15	and	and	CCONJ
admet-189	524	16	dextran	dextran	ADJ
admet-189	524	17	sulfate	sulfate	NOUN
admet-189	524	18	(	(	PUNCT
admet-189	524	19	polyanion	polyanion	NOUN
admet-189	524	20	)	)	PUNCT
admet-189	525	1	[	[	X
admet-189	525	2	130	130	NUM
admet-189	525	3	]	]	PUNCT
admet-189	525	4	.	.	PUNCT
admet-189	526	1	the	the	DET
admet-189	526	2	intracellular	intracellular	ADJ
admet-189	526	3	delivery	delivery	NOUN
admet-189	526	4	of	of	ADP
admet-189	526	5	retinoic	retinoic	NOUN
admet-189	526	6	acid	acid	NOUN
admet-189	526	7	using	use	VERB
admet-189	526	8	nanoparticles	nanoparticle	NOUN
admet-189	526	9	increased	increase	VERB
admet-189	526	10	the	the	DET
admet-189	526	11	differentiation	differentiation	NOUN
admet-189	526	12	of	of	ADP
admet-189	526	13	stem	stem	NOUN
admet-189	526	14	cells	cell	NOUN
admet-189	526	15	into	into	ADP
admet-189	526	16	neurons	neuron	NOUN
admet-189	526	17	as	as	SCONJ
admet-189	526	18	was	be	AUX
admet-189	526	19	confirmed	confirm	VERB
admet-189	526	20	using	use	VERB
admet-189	526	21	gene	gene	NOUN
admet-189	526	22	expression	expression	NOUN
admet-189	526	23	profiles	profile	NOUN
admet-189	526	24	.	.	PUNCT
admet-189	527	1	such	such	ADJ
admet-189	527	2	technologies	technology	NOUN
admet-189	527	3	can	can	AUX
admet-189	527	4	be	be	AUX
admet-189	527	5	of	of	ADP
admet-189	527	6	great	great	ADJ
admet-189	527	7	use	use	NOUN
admet-189	527	8	if	if	SCONJ
admet-189	527	9	nanoparticles	nanoparticle	NOUN
admet-189	527	10	containing	contain	VERB
admet-189	527	11	retinoic	retinoic	NOUN
admet-189	527	12	acid	acid	NOUN
admet-189	527	13	are	be	AUX
admet-189	527	14	manufactured	manufacture	VERB
admet-189	527	15	for	for	ADP
admet-189	527	16	targeting	target	VERB
admet-189	527	17	stem	stem	NOUN
admet-189	527	18	cell	cell	NOUN
admet-189	527	19	sequences	sequence	NOUN
admet-189	527	20	to	to	PART
admet-189	527	21	control	control	VERB
admet-189	527	22	in	in	ADP
admet-189	527	23	time	time	NOUN
admet-189	527	24	and	and	CCONJ
admet-189	527	25	space	space	NOUN
admet-189	527	26	the	the	DET
admet-189	527	27	differentiation	differentiation	NOUN
admet-189	527	28	of	of	ADP
admet-189	527	29	stem	stem	NOUN
admet-189	527	30	cells	cell	NOUN
admet-189	527	31	[	[	X
admet-189	527	32	130	130	NUM
admet-189	527	33	]	]	PUNCT
admet-189	527	34	.	.	PUNCT
admet-189	528	1	scaffold	scaffold	NOUN
admet-189	528	2	design	design	NOUN
admet-189	528	3	:	:	PUNCT
admet-189	528	4	in	in	ADP
admet-189	528	5	addition	addition	NOUN
admet-189	528	6	to	to	ADP
admet-189	528	7	using	use	VERB
admet-189	528	8	small	small	ADJ
admet-189	528	9	molecules	molecule	NOUN
admet-189	528	10	for	for	ADP
admet-189	528	11	the	the	DET
admet-189	528	12	differentiation	differentiation	NOUN
admet-189	528	13	into	into	ADP
admet-189	528	14	a	a	DET
admet-189	528	15	particular	particular	ADJ
admet-189	528	16	lineage	lineage	NOUN
admet-189	528	17	,	,	PUNCT
admet-189	528	18	there	there	PRON
admet-189	528	19	can	can	AUX
admet-189	528	20	be	be	AUX
admet-189	528	21	changes	change	NOUN
admet-189	528	22	made	make	VERB
admet-189	528	23	in	in	ADP
admet-189	528	24	the	the	DET
admet-189	528	25	substrate	substrate	NOUN
admet-189	528	26	too	too	ADV
admet-189	528	27	allowing	allow	VERB
admet-189	528	28	nanoknitting	nanoknitte	VERB
admet-189	528	29	of	of	ADP
admet-189	528	30	neurons	neuron	NOUN
admet-189	528	31	on	on	ADP
admet-189	528	32	scaffolds	scaffold	NOUN
admet-189	528	33	[	[	X
admet-189	528	34	131	131	NUM
admet-189	528	35	]	]	PUNCT
admet-189	528	36	.	.	PUNCT
admet-189	529	1	ni	ni	PROPN
admet-189	529	2	et	et	PROPN
admet-189	529	3	al	al	PROPN
admet-189	529	4	.	.	PROPN
admet-189	529	5	developed	develop	VERB
admet-189	529	6	a	a	DET
admet-189	529	7	self	self	NOUN
admet-189	529	8	-	-	PUNCT
admet-189	529	9	assembling	assemble	VERB
admet-189	529	10	peptide	peptide	NOUN
admet-189	529	11	nanofiber	nanofiber	NOUN
admet-189	529	12	scaffold	scaffold	NOUN
admet-189	529	13	(	(	PUNCT
admet-189	529	14	sapns	sapns	NOUN
admet-189	529	15	)	)	PUNCT
admet-189	529	16	6–10	6–10	NOUN
admet-189	529	17	nm	nm	NOUN
admet-189	529	18	in	in	ADP
admet-189	529	19	diameter	diameter	NOUN
admet-189	529	20	to	to	PART
admet-189	529	21	enhance	enhance	VERB
admet-189	529	22	differentiation	differentiation	NOUN
admet-189	529	23	of	of	ADP
admet-189	529	24	escs	esc	NOUN
admet-189	529	25	as	as	ADV
admet-189	529	26	well	well	ADV
admet-189	529	27	as	as	ADP
admet-189	529	28	ipscs	ipsc	NOUN
admet-189	529	29	into	into	ADP
admet-189	529	30	dopaminergic	dopaminergic	ADJ
admet-189	529	31	neurons	neuron	NOUN
admet-189	529	32	in	in	ADP
admet-189	529	33	a	a	DET
admet-189	529	34	3	3	NUM
admet-189	529	35	-	-	PUNCT
admet-189	529	36	dimensional	dimensional	ADJ
admet-189	529	37	culture	culture	NOUN
admet-189	529	38	[	[	X
admet-189	529	39	132	132	NUM
admet-189	529	40	]	]	PUNCT
admet-189	529	41	.	.	PUNCT
admet-189	530	1	this	this	PRON
admet-189	530	2	was	be	AUX
admet-189	530	3	confirmed	confirm	VERB
admet-189	530	4	using	use	VERB
admet-189	530	5	gene	gene	NOUN
admet-189	530	6	expression	expression	NOUN
admet-189	530	7	,	,	PUNCT
admet-189	530	8	maturation	maturation	NOUN
admet-189	530	9	,	,	PUNCT
admet-189	530	10	immunocytochemistry	immunocytochemistry	NOUN
admet-189	530	11	and	and	CCONJ
admet-189	530	12	dopamine	dopamine	NOUN
admet-189	530	13	release	release	NOUN
admet-189	530	14	all	all	PRON
admet-189	530	15	of	of	ADP
admet-189	530	16	which	which	PRON
admet-189	530	17	proved	prove	VERB
admet-189	530	18	genetically	genetically	ADV
admet-189	530	19	and	and	CCONJ
admet-189	530	20	functionally	functionally	ADV
admet-189	530	21	differentiated	differentiated	ADJ
admet-189	530	22	dopaminergic	dopaminergic	ADJ
admet-189	530	23	neurons	neuron	NOUN
admet-189	530	24	in	in	ADP
admet-189	530	25	the	the	DET
admet-189	530	26	scaffold	scaffold	NOUN
admet-189	530	27	[	[	X
admet-189	530	28	132	132	NUM
admet-189	530	29	]	]	PUNCT
admet-189	530	30	.	.	PUNCT
admet-189	531	1	hence	hence	ADV
admet-189	531	2	,	,	PUNCT
admet-189	531	3	these	these	DET
admet-189	531	4	materials	material	NOUN
admet-189	531	5	have	have	VERB
admet-189	531	6	the	the	DET
admet-189	531	7	potential	potential	NOUN
admet-189	531	8	to	to	PART
admet-189	531	9	be	be	AUX
admet-189	531	10	used	use	VERB
admet-189	531	11	for	for	ADP
admet-189	531	12	neuroprostheses	neuroprosthese	NOUN
admet-189	531	13	.	.	PUNCT
admet-189	532	1	in	in	ADP
admet-189	532	2	addition	addition	NOUN
admet-189	532	3	to	to	ADP
admet-189	532	4	this	this	PRON
admet-189	532	5	,	,	PUNCT
admet-189	532	6	materials	material	NOUN
admet-189	532	7	used	use	VERB
admet-189	532	8	in	in	ADP
admet-189	532	9	neural	neural	ADJ
admet-189	532	10	prosthetic	prosthetic	ADJ
admet-189	532	11	electrodes	electrode	NOUN
admet-189	532	12	have	have	AUX
admet-189	532	13	also	also	ADV
admet-189	532	14	been	be	AUX
admet-189	532	15	used	use	VERB
admet-189	532	16	in	in	ADP
admet-189	532	17	tissue	tissue	NOUN
admet-189	532	18	engineering	engineering	NOUN
admet-189	532	19	.	.	PUNCT
admet-189	533	1	conductive	conductive	ADJ
admet-189	533	2	polymer	polymer	NOUN
admet-189	533	3	hydrogels	hydrogel	NOUN
admet-189	533	4	(	(	PUNCT
admet-189	533	5	cph	cph	NOUN
admet-189	533	6	)	)	PUNCT
admet-189	533	7	have	have	VERB
admet-189	533	8	the	the	DET
admet-189	533	9	advantage	advantage	NOUN
admet-189	533	10	of	of	ADP
admet-189	533	11	allowing	allow	VERB
admet-189	533	12	cell	cell	NOUN
admet-189	533	13	immobilization	immobilization	NOUN
admet-189	533	14	while	while	SCONJ
admet-189	533	15	increasing	increase	VERB
admet-189	533	16	the	the	DET
admet-189	533	17	surface	surface	NOUN
admet-189	533	18	area	area	NOUN
admet-189	533	19	and	and	CCONJ
admet-189	533	20	electrical	electrical	ADJ
admet-189	533	21	properties	property	NOUN
admet-189	533	22	necessary	necessary	ADJ
admet-189	533	23	for	for	ADP
admet-189	533	24	nerve	nerve	NOUN
admet-189	533	25	growth	growth	NOUN
admet-189	533	26	and	and	CCONJ
admet-189	533	27	regeneration	regeneration	NOUN
admet-189	533	28	[	[	X
admet-189	533	29	117,118,120	117,118,120	NUM
admet-189	533	30	]	]	PUNCT
admet-189	533	31	.	.	PUNCT
admet-189	534	1	thus	thus	ADV
admet-189	534	2	,	,	PUNCT
admet-189	534	3	nanotechnology	nanotechnology	NOUN
admet-189	534	4	-	-	PUNCT
admet-189	534	5	based	base	VERB
admet-189	534	6	platforms	platform	NOUN
admet-189	534	7	are	be	AUX
admet-189	534	8	increasingly	increasingly	ADV
admet-189	534	9	being	be	AUX
admet-189	534	10	used	use	VERB
admet-189	534	11	to	to	PART
admet-189	534	12	tackle	tackle	VERB
admet-189	534	13	the	the	DET
admet-189	534	14	challenges	challenge	NOUN
admet-189	534	15	of	of	ADP
admet-189	534	16	stem	stem	NOUN
admet-189	534	17	-	-	PUNCT
admet-189	534	18	cell	cell	NOUN
admet-189	534	19	delivery	delivery	NOUN
admet-189	534	20	.	.	PUNCT
admet-189	535	1	the	the	DET
admet-189	535	2	present	present	ADJ
admet-189	535	3	day	day	NOUN
admet-189	535	4	platforms	platform	NOUN
admet-189	535	5	based	base	VERB
admet-189	535	6	on	on	ADP
admet-189	535	7	nanotechnology	nanotechnology	NOUN
admet-189	535	8	would	would	AUX
admet-189	535	9	allow	allow	VERB
admet-189	535	10	a	a	DET
admet-189	535	11	more	more	ADV
admet-189	535	12	precise	precise	ADJ
admet-189	535	13	and	and	CCONJ
admet-189	535	14	accurate	accurate	ADJ
admet-189	535	15	delivery	delivery	NOUN
admet-189	535	16	of	of	ADP
admet-189	535	17	stem	stem	NOUN
admet-189	535	18	cells	cell	NOUN
admet-189	535	19	for	for	ADP
admet-189	535	20	the	the	DET
admet-189	535	21	management	management	NOUN
admet-189	535	22	of	of	ADP
admet-189	535	23	parkinson	parkinson	NOUN
admet-189	535	24	’s	’s	PART
admet-189	535	25	disease	disease	NOUN
admet-189	535	26	.	.	PUNCT
admet-189	536	1	a	a	DET
admet-189	536	2	brief	brief	ADJ
admet-189	536	3	summary	summary	NOUN
admet-189	536	4	of	of	ADP
admet-189	536	5	the	the	DET
admet-189	536	6	use	use	NOUN
admet-189	536	7	of	of	ADP
admet-189	536	8	nanotechnology	nanotechnology	NOUN
admet-189	536	9	in	in	ADP
admet-189	536	10	these	these	DET
admet-189	536	11	therapies	therapy	NOUN
admet-189	536	12	is	be	AUX
admet-189	536	13	represented	represent	VERB
admet-189	536	14	in	in	ADP
admet-189	536	15	figure	figure	NOUN
admet-189	536	16	7	7	NUM
admet-189	536	17	.	.	PUNCT
admet-189	536	18	admet	admet	PROPN
admet-189	536	19	&	&	CCONJ
admet-189	536	20	dmpk	dmpk	PROPN
admet-189	536	21	3(3	3(3	NUM
admet-189	536	22	)	)	PUNCT
admet-189	536	23	(	(	PUNCT
admet-189	536	24	2015	2015	NUM
admet-189	536	25	)	)	PUNCT
admet-189	536	26	155	155	NUM
admet-189	536	27	-	-	SYM
admet-189	536	28	181	181	NUM
admet-189	536	29	nanotechnology	nanotechnology	NOUN
admet-189	536	30	platforms	platform	NOUN
admet-189	536	31	in	in	ADP
admet-189	536	32	parkinson	parkinson	NOUN
admet-189	536	33	’s	’s	PART
admet-189	536	34	disease	disease	NOUN
admet-189	536	35	doi	doi	NOUN
admet-189	536	36	:	:	PUNCT
admet-189	536	37	10.5599	10.5599	NUM
admet-189	536	38	/	/	SYM
admet-189	536	39	admet.3.3.189	admet.3.3.189	ADP
admet-189	536	40	175	175	NUM
admet-189	536	41	figure	figure	NOUN
admet-189	536	42	7	7	NUM
admet-189	536	43	.	.	PUNCT
admet-189	536	44	nanotechnology	nanotechnology	NOUN
admet-189	536	45	-	-	PUNCT
admet-189	536	46	based	base	VERB
admet-189	536	47	platforms	platform	NOUN
admet-189	536	48	for	for	ADP
admet-189	536	49	the	the	DET
admet-189	536	50	management	management	NOUN
admet-189	536	51	of	of	ADP
admet-189	536	52	parkinson	parkinson	NOUN
admet-189	536	53	’s	’s	PART
admet-189	536	54	disease	disease	NOUN
admet-189	536	55	translation	translation	NOUN
admet-189	536	56	,	,	PUNCT
admet-189	536	57	future	future	ADJ
admet-189	536	58	prospects	prospect	NOUN
admet-189	536	59	and	and	CCONJ
admet-189	536	60	concerns	concern	NOUN
admet-189	536	61	the	the	DET
admet-189	536	62	increased	increase	VERB
admet-189	536	63	awareness	awareness	NOUN
admet-189	536	64	of	of	ADP
admet-189	536	65	pd	pd	PROPN
admet-189	536	66	and	and	CCONJ
admet-189	536	67	the	the	DET
admet-189	536	68	accelerated	accelerated	ADJ
admet-189	536	69	research	research	NOUN
admet-189	536	70	towards	towards	ADP
admet-189	536	71	its	its	PRON
admet-189	536	72	management	management	NOUN
admet-189	536	73	has	have	AUX
admet-189	536	74	lead	lead	VERB
admet-189	536	75	to	to	ADP
admet-189	536	76	the	the	DET
admet-189	536	77	infusion	infusion	NOUN
admet-189	536	78	of	of	ADP
admet-189	536	79	a	a	DET
admet-189	536	80	number	number	NOUN
admet-189	536	81	of	of	ADP
admet-189	536	82	technologies	technology	NOUN
admet-189	536	83	into	into	ADP
admet-189	536	84	the	the	DET
admet-189	536	85	scenario	scenario	NOUN
admet-189	536	86	.	.	PUNCT
admet-189	537	1	nanotechnology	nanotechnology	NOUN
admet-189	537	2	is	be	AUX
admet-189	537	3	a	a	DET
admet-189	537	4	novel	novel	ADJ
admet-189	537	5	and	and	CCONJ
admet-189	537	6	versatile	versatile	ADJ
admet-189	537	7	addition	addition	NOUN
admet-189	537	8	to	to	ADP
admet-189	537	9	the	the	DET
admet-189	537	10	fight	fight	NOUN
admet-189	537	11	against	against	ADP
admet-189	537	12	pd	pd	PROPN
admet-189	537	13	.	.	PUNCT
admet-189	538	1	there	there	PRON
admet-189	538	2	have	have	AUX
admet-189	538	3	been	be	AUX
admet-189	538	4	efforts	effort	NOUN
admet-189	538	5	in	in	ADP
admet-189	538	6	accelerating	accelerate	VERB
admet-189	538	7	research	research	NOUN
admet-189	538	8	in	in	ADP
admet-189	538	9	the	the	DET
admet-189	538	10	identification	identification	NOUN
admet-189	538	11	of	of	ADP
admet-189	538	12	novel	novel	ADJ
admet-189	538	13	biomarkers	biomarker	NOUN
admet-189	538	14	and	and	CCONJ
admet-189	538	15	strategies	strategy	NOUN
admet-189	538	16	for	for	ADP
admet-189	538	17	the	the	DET
admet-189	538	18	cure	cure	NOUN
admet-189	538	19	for	for	ADP
admet-189	538	20	pd	pd	PROPN
admet-189	538	21	.	.	PUNCT
admet-189	539	1	this	this	PRON
admet-189	539	2	has	have	AUX
admet-189	539	3	led	lead	VERB
admet-189	539	4	to	to	ADP
admet-189	539	5	a	a	DET
admet-189	539	6	lot	lot	NOUN
admet-189	539	7	of	of	ADP
admet-189	539	8	research	research	NOUN
admet-189	539	9	reach	reach	VERB
admet-189	539	10	from	from	ADP
admet-189	539	11	labs	lab	NOUN
admet-189	539	12	to	to	ADP
admet-189	539	13	the	the	DET
admet-189	539	14	bedside	bedside	NOUN
admet-189	539	15	.	.	PUNCT
admet-189	540	1	nanotechnology	nanotechnology	PROPN
admet-189	540	2	has	have	VERB
admet-189	540	3	the	the	DET
admet-189	540	4	ability	ability	NOUN
admet-189	540	5	to	to	PART
admet-189	540	6	develop	develop	VERB
admet-189	540	7	smarter	smart	ADJ
admet-189	540	8	sensors	sensor	NOUN
admet-189	540	9	for	for	ADP
admet-189	540	10	the	the	DET
admet-189	540	11	diagnosis	diagnosis	NOUN
admet-189	540	12	of	of	ADP
admet-189	540	13	pd	pd	NOUN
admet-189	540	14	using	use	VERB
admet-189	540	15	these	these	DET
admet-189	540	16	novel	novel	ADJ
admet-189	540	17	biomarkers	biomarker	NOUN
admet-189	540	18	and	and	CCONJ
admet-189	540	19	imaging	imaging	NOUN
admet-189	540	20	modalities	modality	NOUN
admet-189	540	21	.	.	PUNCT
admet-189	541	1	it	it	PRON
admet-189	541	2	is	be	AUX
admet-189	541	3	also	also	ADV
admet-189	541	4	being	be	AUX
admet-189	541	5	used	use	VERB
admet-189	541	6	for	for	ADP
admet-189	541	7	the	the	DET
admet-189	541	8	targeted	target	VERB
admet-189	541	9	treatment	treatment	NOUN
admet-189	541	10	of	of	ADP
admet-189	541	11	pd	pd	PROPN
admet-189	541	12	,	,	PUNCT
admet-189	541	13	in	in	ADP
admet-189	541	14	neuroprotection	neuroprotection	NOUN
admet-189	541	15	and	and	CCONJ
admet-189	541	16	in	in	ADP
admet-189	541	17	stem	stem	NOUN
admet-189	541	18	cell	cell	NOUN
admet-189	541	19	therapies	therapy	NOUN
admet-189	541	20	.	.	PUNCT
admet-189	542	1	multinational	multinational	ADJ
admet-189	542	2	technology	technology	NOUN
admet-189	542	3	companies	company	NOUN
admet-189	542	4	are	be	AUX
admet-189	542	5	also	also	ADV
admet-189	542	6	entering	enter	VERB
admet-189	542	7	the	the	DET
admet-189	542	8	arena	arena	NOUN
admet-189	542	9	of	of	ADP
admet-189	542	10	nanotechnology	nanotechnology	NOUN
admet-189	542	11	to	to	PART
admet-189	542	12	treat	treat	VERB
admet-189	542	13	parkinson	parkinson	NOUN
admet-189	542	14	’s	’s	PART
admet-189	542	15	disease	disease	NOUN
admet-189	542	16	.	.	PUNCT
admet-189	543	1	google	google	PROPN
admet-189	543	2	inc	inc	PROPN
admet-189	543	3	.	.	PROPN
admet-189	543	4	has	have	AUX
admet-189	543	5	recently	recently	ADV
admet-189	543	6	filed	file	VERB
admet-189	543	7	a	a	DET
admet-189	543	8	patent	patent	NOUN
admet-189	543	9	for	for	ADP
admet-189	543	10	a	a	DET
admet-189	543	11	wearable	wearable	ADJ
admet-189	543	12	device	device	NOUN
admet-189	543	13	in	in	ADP
admet-189	543	14	the	the	DET
admet-189	543	15	form	form	NOUN
admet-189	543	16	of	of	ADP
admet-189	543	17	a	a	DET
admet-189	543	18	watch	watch	NOUN
admet-189	543	19	or	or	CCONJ
admet-189	543	20	bracelet	bracelet	NOUN
admet-189	543	21	that	that	PRON
admet-189	543	22	can	can	AUX
admet-189	543	23	direct	direct	VERB
admet-189	543	24	functionalized	functionalized	ADJ
admet-189	543	25	nanoparticles	nanoparticle	NOUN
admet-189	543	26	(	(	PUNCT
admet-189	543	27	like	like	ADP
admet-189	543	28	magnetic	magnetic	ADJ
admet-189	543	29	nanoparticles	nanoparticle	NOUN
admet-189	543	30	through	through	ADP
admet-189	543	31	the	the	DET
admet-189	543	32	magnetic	magnetic	ADJ
admet-189	543	33	field	field	NOUN
admet-189	543	34	generated	generate	VERB
admet-189	543	35	by	by	ADP
admet-189	543	36	the	the	DET
admet-189	543	37	device	device	NOUN
admet-189	543	38	)	)	PUNCT
admet-189	543	39	into	into	ADP
admet-189	543	40	the	the	DET
admet-189	543	41	subsurface	subsurface	NOUN
admet-189	543	42	vasculature	vasculature	NOUN
admet-189	543	43	present	present	ADJ
admet-189	543	44	close	close	ADV
admet-189	543	45	to	to	ADP
admet-189	543	46	the	the	DET
admet-189	543	47	device	device	NOUN
admet-189	543	48	[	[	X
admet-189	543	49	133	133	NUM
admet-189	543	50	]	]	PUNCT
admet-189	543	51	.	.	PUNCT
admet-189	544	1	the	the	DET
admet-189	544	2	patent	patent	NOUN
admet-189	544	3	claims	claim	VERB
admet-189	544	4	that	that	SCONJ
admet-189	544	5	there	there	PRON
admet-189	544	6	is	be	VERB
admet-189	544	7	a	a	DET
admet-189	544	8	potential	potential	NOUN
admet-189	544	9	for	for	ADP
admet-189	544	10	the	the	DET
admet-189	544	11	use	use	NOUN
admet-189	544	12	of	of	ADP
admet-189	544	13	such	such	ADJ
admet-189	544	14	devices	device	NOUN
admet-189	544	15	in	in	ADP
admet-189	544	16	the	the	DET
admet-189	544	17	treatment	treatment	NOUN
admet-189	544	18	of	of	ADP
admet-189	544	19	pd	pd	NOUN
admet-189	544	20	by	by	ADP
admet-189	544	21	targeting	target	VERB
admet-189	544	22	certain	certain	ADJ
admet-189	544	23	proteins	protein	NOUN
admet-189	544	24	[	[	X
admet-189	544	25	133	133	NUM
admet-189	544	26	]	]	PUNCT
admet-189	544	27	.	.	PUNCT
admet-189	545	1	besides	besides	SCONJ
admet-189	545	2	,	,	PUNCT
admet-189	545	3	the	the	DET
admet-189	545	4	clinical	clinical	ADJ
admet-189	545	5	translation	translation	NOUN
admet-189	545	6	of	of	ADP
admet-189	545	7	research	research	NOUN
admet-189	545	8	has	have	AUX
admet-189	545	9	lead	lead	VERB
admet-189	545	10	to	to	ADP
admet-189	545	11	the	the	DET
admet-189	545	12	development	development	NOUN
admet-189	545	13	of	of	ADP
admet-189	545	14	a	a	DET
admet-189	545	15	number	number	NOUN
admet-189	545	16	of	of	ADP
admet-189	545	17	commercial	commercial	ADJ
admet-189	545	18	entities	entity	NOUN
admet-189	545	19	.	.	PUNCT
admet-189	546	1	the	the	DET
admet-189	546	2	bronx	bronx	PROPN
admet-189	546	3	project	project	PROPN
admet-189	546	4	,	,	PUNCT
admet-189	546	5	inc	inc	PROPN
admet-189	546	6	.	.	PROPN
admet-189	546	7	(	(	PUNCT
admet-189	546	8	tbp	tbp	NOUN
admet-189	546	9	)	)	PUNCT
admet-189	546	10	,	,	PUNCT
admet-189	546	11	tego	tego	PROPN
admet-189	546	12	biosciences	biosciences	PROPN
admet-189	546	13	corporation	corporation	PROPN
admet-189	546	14	(	(	PUNCT
admet-189	546	15	tego	tego	NOUN
admet-189	546	16	)	)	PUNCT
admet-189	546	17	and	and	CCONJ
admet-189	546	18	luna	luna	PROPN
admet-189	546	19	innovations	innovation	NOUN
admet-189	546	20	incorporated	incorporate	VERB
admet-189	546	21	(	(	PUNCT
admet-189	546	22	luna	luna	PROPN
admet-189	546	23	)	)	PUNCT
admet-189	547	1	[	[	X
admet-189	547	2	108	108	NUM
admet-189	547	3	]	]	PUNCT
admet-189	547	4	are	be	AUX
admet-189	547	5	involved	involve	VERB
admet-189	547	6	in	in	ADP
admet-189	547	7	the	the	DET
admet-189	547	8	development	development	NOUN
admet-189	547	9	of	of	ADP
admet-189	547	10	fullerenes	fullerene	NOUN
admet-189	547	11	for	for	ADP
admet-189	547	12	neuroprotection	neuroprotection	NOUN
admet-189	547	13	in	in	ADP
admet-189	547	14	pd	pd	PROPN
admet-189	547	15	.	.	PROPN
admet-189	547	16	parkinson	parkinson	PROPN
admet-189	547	17	’s	’s	PART
admet-189	547	18	pen	pen	NOUN
admet-189	547	19	(	(	PUNCT
admet-189	547	20	by	by	ADP
admet-189	547	21	manus	manus	PROPN
admet-189	547	22	neurodynamica	neurodynamica	PROPN
admet-189	547	23	ltd	ltd	PROPN
admet-189	547	24	.	.	PROPN
admet-189	547	25	)	)	PUNCT
admet-189	547	26	is	be	AUX
admet-189	547	27	another	another	DET
admet-189	547	28	patented	patented	ADJ
admet-189	547	29	technology	technology	NOUN
admet-189	547	30	that	that	PRON
admet-189	547	31	uses	use	VERB
admet-189	547	32	the	the	DET
admet-189	547	33	changes	change	NOUN
admet-189	547	34	in	in	ADP
admet-189	547	35	handwriting	handwriting	NOUN
admet-189	547	36	in	in	ADP
admet-189	547	37	combination	combination	NOUN
admet-189	547	38	with	with	ADP
admet-189	547	39	a	a	DET
admet-189	547	40	sensor	sensor	NOUN
admet-189	547	41	device	device	NOUN
admet-189	547	42	on	on	ADP
admet-189	547	43	the	the	DET
admet-189	547	44	pen	pen	NOUN
admet-189	547	45	to	to	PART
admet-189	547	46	analyze	analyze	VERB
admet-189	547	47	the	the	DET
admet-189	547	48	force	force	NOUN
admet-189	547	49	exerted	exert	VERB
admet-189	547	50	by	by	ADP
admet-189	547	51	each	each	PRON
admet-189	547	52	of	of	ADP
admet-189	547	53	the	the	DET
admet-189	547	54	fingers	finger	NOUN
admet-189	547	55	,	,	PUNCT
admet-189	547	56	and	and	CCONJ
admet-189	547	57	the	the	DET
admet-189	547	58	changes	change	NOUN
admet-189	547	59	in	in	ADP
admet-189	547	60	handwriting	handwriting	NOUN
admet-189	547	61	[	[	X
admet-189	547	62	73	73	NUM
admet-189	547	63	]	]	PUNCT
admet-189	547	64	.	.	PUNCT
admet-189	548	1	such	such	ADJ
admet-189	548	2	pressure	pressure	NOUN
admet-189	548	3	sensors	sensor	NOUN
admet-189	548	4	and	and	CCONJ
admet-189	548	5	detectors	detector	NOUN
admet-189	548	6	can	can	AUX
admet-189	548	7	be	be	AUX
admet-189	548	8	of	of	ADP
admet-189	548	9	use	use	NOUN
admet-189	548	10	to	to	PART
admet-189	548	11	detect	detect	VERB
admet-189	548	12	pd	pd	PROPN
admet-189	548	13	.	.	PROPN
admet-189	548	14	parkinson	parkinson	PROPN
admet-189	548	15	’s	’s	PART
admet-189	548	16	pen	pen	NOUN
admet-189	548	17	itself	itself	PRON
admet-189	548	18	in	in	ADP
admet-189	548	19	its	its	PRON
admet-189	548	20	initial	initial	ADJ
admet-189	548	21	testing	testing	NOUN
admet-189	548	22	was	be	AUX
admet-189	548	23	able	able	ADJ
admet-189	548	24	to	to	PART
admet-189	548	25	distinguish	distinguish	VERB
admet-189	548	26	10	10	NUM
admet-189	548	27	people	people	NOUN
admet-189	548	28	with	with	ADP
admet-189	548	29	pd	pd	PROPN
admet-189	548	30	from	from	ADP
admet-189	548	31	ageand	ageand	NOUN
admet-189	548	32	sexmatched	sexmatche	VERB
admet-189	548	33	controls	control	NOUN
admet-189	548	34	with	with	ADP
admet-189	548	35	90	90	NUM
admet-189	548	36	%	%	NOUN
admet-189	548	37	sensitivity	sensitivity	NOUN
admet-189	548	38	and	and	CCONJ
admet-189	548	39	80	80	NUM
admet-189	548	40	%	%	NOUN
admet-189	548	41	specificity	specificity	NOUN
admet-189	549	1	[	[	X
admet-189	549	2	134	134	NUM
admet-189	549	3	]	]	PUNCT
admet-189	549	4	.	.	PUNCT
admet-189	550	1	a	a	DET
admet-189	550	2	clinical	clinical	ADJ
admet-189	550	3	trial	trial	NOUN
admet-189	550	4	with	with	ADP
admet-189	550	5	a	a	DET
admet-189	550	6	larger	large	ADJ
admet-189	550	7	sample	sample	NOUN
admet-189	550	8	size	size	NOUN
admet-189	550	9	is	be	AUX
admet-189	550	10	underway	underway	ADJ
admet-189	550	11	to	to	PART
admet-189	550	12	confirm	confirm	VERB
admet-189	550	13	the	the	DET
admet-189	550	14	sensitivity	sensitivity	NOUN
admet-189	550	15	and	and	CCONJ
admet-189	550	16	specificity	specificity	NOUN
admet-189	550	17	of	of	ADP
admet-189	550	18	the	the	DET
admet-189	550	19	promising	promising	ADJ
admet-189	550	20	device	device	NOUN
admet-189	550	21	[	[	X
admet-189	550	22	134	134	NUM
admet-189	550	23	]	]	PUNCT
admet-189	550	24	.	.	PUNCT
admet-189	551	1	this	this	DET
admet-189	551	2	technology	technology	NOUN
admet-189	551	3	will	will	AUX
admet-189	551	4	have	have	VERB
admet-189	551	5	applications	application	NOUN
admet-189	551	6	in	in	ADP
admet-189	551	7	diagnostics	diagnostic	NOUN
admet-189	551	8	,	,	PUNCT
admet-189	551	9	pre	pre	ADJ
admet-189	551	10	-	-	ADJ
admet-189	551	11	symptomatic	symptomatic	ADJ
admet-189	551	12	screening	screening	NOUN
admet-189	551	13	,	,	PUNCT
admet-189	551	14	disease	disease	NOUN
admet-189	551	15	monitoring	monitoring	NOUN
admet-189	551	16	,	,	PUNCT
admet-189	551	17	treatment	treatment	NOUN
admet-189	551	18	response	response	NOUN
admet-189	551	19	and	and	CCONJ
admet-189	551	20	rehabilitation	rehabilitation	NOUN
admet-189	551	21	.	.	PUNCT
admet-189	552	1	the	the	DET
admet-189	552	2	company	company	NOUN
admet-189	552	3	is	be	AUX
admet-189	552	4	currently	currently	ADV
admet-189	552	5	conducting	conduct	VERB
admet-189	552	6	clinical	clinical	ADJ
admet-189	552	7	trials	trial	NOUN
admet-189	552	8	to	to	ADP
admet-189	552	9	this	this	DET
admet-189	552	10	end	end	NOUN
admet-189	552	11	.	.	PUNCT
admet-189	553	1	thus	thus	ADV
admet-189	553	2	,	,	PUNCT
admet-189	553	3	there	there	PRON
admet-189	553	4	is	be	VERB
admet-189	553	5	a	a	DET
admet-189	553	6	lot	lot	NOUN
admet-189	553	7	of	of	ADP
admet-189	553	8	translation	translation	NOUN
admet-189	553	9	that	that	PRON
admet-189	553	10	is	be	AUX
admet-189	553	11	taking	take	VERB
admet-189	553	12	place	place	NOUN
admet-189	553	13	from	from	ADP
admet-189	553	14	diagnosis	diagnosis	NOUN
admet-189	553	15	to	to	ADP
admet-189	553	16	rehabilitation	rehabilitation	NOUN
admet-189	553	17	of	of	ADP
admet-189	553	18	pd	pd	PROPN
admet-189	553	19	patients	patient	NOUN
admet-189	553	20	.	.	PUNCT
admet-189	554	1	r.	r.	PROPN
admet-189	554	2	banerjee	banerjee	PROPN
admet-189	554	3	et	et	PROPN
admet-189	554	4	al	al	PROPN
admet-189	554	5	.	.	PROPN
admet-189	554	6	admet	admet	PROPN
admet-189	554	7	&	&	CCONJ
admet-189	554	8	dmpk	dmpk	PROPN
admet-189	554	9	3(3	3(3	NUM
admet-189	554	10	)	)	PUNCT
admet-189	554	11	(	(	PUNCT
admet-189	554	12	2015	2015	NUM
admet-189	554	13	)	)	PUNCT
admet-189	554	14	155	155	NUM
admet-189	554	15	-	-	SYM
admet-189	554	16	181	181	NUM
admet-189	554	17	176	176	NUM
admet-189	554	18	another	another	DET
admet-189	554	19	area	area	NOUN
admet-189	554	20	that	that	PRON
admet-189	554	21	is	be	AUX
admet-189	554	22	developing	develop	VERB
admet-189	554	23	a	a	DET
admet-189	554	24	lot	lot	NOUN
admet-189	554	25	in	in	ADP
admet-189	554	26	pd	pd	PROPN
admet-189	554	27	is	be	AUX
admet-189	554	28	the	the	DET
admet-189	554	29	use	use	NOUN
admet-189	554	30	of	of	ADP
admet-189	554	31	stem	stem	NOUN
admet-189	554	32	cells	cell	NOUN
admet-189	554	33	.	.	PUNCT
admet-189	555	1	nanotechnology	nanotechnology	PROPN
admet-189	555	2	affords	afford	VERB
admet-189	555	3	a	a	DET
admet-189	555	4	targeted	target	VERB
admet-189	555	5	and	and	CCONJ
admet-189	555	6	controlled	control	VERB
admet-189	555	7	delivery	delivery	NOUN
admet-189	555	8	and	and	CCONJ
admet-189	555	9	differentiation	differentiation	NOUN
admet-189	555	10	of	of	ADP
admet-189	555	11	stem	stem	NOUN
admet-189	555	12	cells	cell	NOUN
admet-189	555	13	for	for	ADP
admet-189	555	14	the	the	DET
admet-189	555	15	therapy	therapy	NOUN
admet-189	555	16	of	of	ADP
admet-189	555	17	pd	pd	PROPN
admet-189	555	18	.	.	PUNCT
admet-189	556	1	however	however	ADV
admet-189	556	2	,	,	PUNCT
admet-189	556	3	one	one	NUM
admet-189	556	4	of	of	ADP
admet-189	556	5	the	the	DET
admet-189	556	6	biggest	big	ADJ
admet-189	556	7	concerns	concern	NOUN
admet-189	556	8	in	in	ADP
admet-189	556	9	the	the	DET
admet-189	556	10	present	present	ADJ
admet-189	556	11	day	day	NOUN
admet-189	556	12	is	be	AUX
admet-189	556	13	the	the	DET
admet-189	556	14	development	development	NOUN
admet-189	556	15	of	of	ADP
admet-189	556	16	treatments	treatment	NOUN
admet-189	556	17	of	of	ADP
admet-189	556	18	pd	pd	PROPN
admet-189	556	19	using	use	VERB
admet-189	556	20	unproven	unproven	ADJ
admet-189	556	21	cell	cell	NOUN
admet-189	556	22	-	-	PUNCT
admet-189	556	23	based	base	VERB
admet-189	556	24	treatments	treatment	NOUN
admet-189	556	25	which	which	PRON
admet-189	556	26	pose	pose	VERB
admet-189	556	27	serious	serious	ADJ
admet-189	556	28	threats	threat	NOUN
admet-189	556	29	to	to	PART
admet-189	556	30	research	research	VERB
admet-189	556	31	translation	translation	NOUN
admet-189	556	32	[	[	X
admet-189	556	33	128	128	NUM
admet-189	556	34	]	]	PUNCT
admet-189	556	35	.	.	PUNCT
admet-189	557	1	these	these	DET
admet-189	557	2	therapies	therapy	NOUN
admet-189	557	3	pose	pose	VERB
admet-189	557	4	increased	increase	VERB
admet-189	557	5	risk	risk	NOUN
admet-189	557	6	of	of	ADP
admet-189	557	7	tumor	tumor	NOUN
admet-189	557	8	formation	formation	NOUN
admet-189	557	9	[	[	X
admet-189	557	10	126	126	NUM
admet-189	557	11	]	]	PUNCT
admet-189	557	12	.	.	PUNCT
admet-189	558	1	such	such	ADJ
admet-189	558	2	therapies	therapy	NOUN
admet-189	558	3	continue	continue	VERB
admet-189	558	4	to	to	PART
admet-189	558	5	be	be	AUX
admet-189	558	6	performed	perform	VERB
admet-189	558	7	without	without	ADP
admet-189	558	8	intensive	intensive	ADJ
admet-189	558	9	testing	testing	NOUN
admet-189	558	10	in	in	ADP
admet-189	558	11	vitro	vitro	X
admet-189	558	12	and	and	CCONJ
admet-189	558	13	in	in	ADP
admet-189	558	14	vivo	vivo	NOUN
admet-189	558	15	and	and	CCONJ
admet-189	558	16	pose	pose	VERB
admet-189	558	17	a	a	DET
admet-189	558	18	serious	serious	ADJ
admet-189	558	19	risk	risk	NOUN
admet-189	558	20	to	to	PART
admet-189	558	21	jeopardize	jeopardize	VERB
admet-189	558	22	the	the	DET
admet-189	558	23	spark	spark	NOUN
admet-189	558	24	of	of	ADP
admet-189	558	25	hope	hope	NOUN
admet-189	558	26	that	that	PRON
admet-189	558	27	is	be	AUX
admet-189	558	28	gradually	gradually	ADV
admet-189	558	29	infused	infuse	VERB
admet-189	558	30	in	in	ADP
admet-189	558	31	the	the	DET
admet-189	558	32	sphere	sphere	NOUN
admet-189	558	33	due	due	ADP
admet-189	558	34	to	to	ADP
admet-189	558	35	the	the	DET
admet-189	558	36	advent	advent	NOUN
admet-189	558	37	of	of	ADP
admet-189	558	38	tissue	tissue	NOUN
admet-189	558	39	engineering	engineering	NOUN
admet-189	558	40	and	and	CCONJ
admet-189	558	41	nanotechnology	nanotechnology	NOUN
admet-189	559	1	[	[	X
admet-189	559	2	128	128	NUM
admet-189	559	3	]	]	PUNCT
admet-189	559	4	.	.	PUNCT
admet-189	560	1	in	in	ADP
admet-189	560	2	addition	addition	NOUN
admet-189	560	3	to	to	ADP
admet-189	560	4	this	this	PRON
admet-189	560	5	,	,	PUNCT
admet-189	560	6	there	there	PRON
admet-189	560	7	are	be	VERB
admet-189	560	8	ethical	ethical	ADJ
admet-189	560	9	concerns	concern	NOUN
admet-189	560	10	raised	raise	VERB
admet-189	560	11	regarding	regard	VERB
admet-189	560	12	neurology	neurology	NOUN
admet-189	560	13	and	and	CCONJ
admet-189	560	14	nanotechnology	nanotechnology	NOUN
admet-189	560	15	and	and	CCONJ
admet-189	560	16	their	their	PRON
admet-189	560	17	potential	potential	ADJ
admet-189	560	18	impact	impact	NOUN
admet-189	560	19	for	for	ADP
admet-189	560	20	which	which	PRON
admet-189	560	21	there	there	PRON
admet-189	560	22	is	be	VERB
admet-189	560	23	a	a	DET
admet-189	560	24	need	need	NOUN
admet-189	560	25	for	for	ADP
admet-189	560	26	a	a	DET
admet-189	560	27	multidisciplinary	multidisciplinary	ADJ
admet-189	560	28	bioethical	bioethical	ADJ
admet-189	560	29	enquiry	enquiry	NOUN
admet-189	560	30	[	[	X
admet-189	560	31	135	135	NUM
admet-189	560	32	]	]	PUNCT
admet-189	560	33	.	.	PUNCT
admet-189	561	1	also	also	ADV
admet-189	561	2	,	,	PUNCT
admet-189	561	3	there	there	PRON
admet-189	561	4	are	be	VERB
admet-189	561	5	conflicting	conflicting	ADJ
admet-189	561	6	reports	report	NOUN
admet-189	561	7	regarding	regard	VERB
admet-189	561	8	toxicity	toxicity	NOUN
admet-189	561	9	of	of	ADP
admet-189	561	10	certain	certain	ADJ
admet-189	561	11	nanoparticles	nanoparticle	NOUN
admet-189	561	12	which	which	PRON
admet-189	561	13	cross	cross	VERB
admet-189	561	14	the	the	DET
admet-189	561	15	blood	blood	NOUN
admet-189	561	16	brain	brain	NOUN
admet-189	561	17	barrier	barrier	NOUN
admet-189	561	18	[	[	X
admet-189	561	19	136	136	NUM
admet-189	561	20	-	-	SYM
admet-189	561	21	138	138	NUM
admet-189	561	22	]	]	PUNCT
admet-189	561	23	.	.	PUNCT
admet-189	562	1	this	this	PRON
admet-189	562	2	has	have	AUX
admet-189	562	3	called	call	VERB
admet-189	562	4	for	for	ADP
admet-189	562	5	further	further	ADJ
admet-189	562	6	evaluation	evaluation	NOUN
admet-189	562	7	of	of	ADP
admet-189	562	8	nanoparticles	nanoparticle	NOUN
admet-189	562	9	for	for	ADP
admet-189	562	10	surface	surface	NOUN
admet-189	562	11	properties	property	NOUN
admet-189	562	12	,	,	PUNCT
admet-189	562	13	size	size	NOUN
admet-189	562	14	and	and	CCONJ
admet-189	562	15	constituents	constituent	NOUN
admet-189	562	16	for	for	ADP
admet-189	562	17	finetuning	finetune	VERB
admet-189	562	18	the	the	DET
admet-189	562	19	therapeutic	therapeutic	ADJ
admet-189	562	20	effects	effect	NOUN
admet-189	562	21	while	while	SCONJ
admet-189	562	22	avoiding	avoid	VERB
admet-189	562	23	toxic	toxic	ADJ
admet-189	562	24	effects	effect	NOUN
admet-189	562	25	[	[	X
admet-189	562	26	136	136	NUM
admet-189	562	27	]	]	PUNCT
admet-189	562	28	.	.	PUNCT
admet-189	563	1	for	for	ADP
admet-189	563	2	drug	drug	NOUN
admet-189	563	3	delivery	delivery	NOUN
admet-189	563	4	formulations	formulation	NOUN
admet-189	563	5	,	,	PUNCT
admet-189	563	6	it	it	PRON
admet-189	563	7	is	be	AUX
admet-189	563	8	imperative	imperative	ADJ
admet-189	563	9	to	to	PART
admet-189	563	10	increase	increase	VERB
admet-189	563	11	the	the	DET
admet-189	563	12	therapeutic	therapeutic	ADJ
admet-189	563	13	window	window	NOUN
admet-189	563	14	which	which	PRON
admet-189	563	15	is	be	AUX
admet-189	563	16	the	the	DET
admet-189	563	17	range	range	NOUN
admet-189	563	18	of	of	ADP
admet-189	563	19	dosage	dosage	NOUN
admet-189	563	20	that	that	PRON
admet-189	563	21	can	can	AUX
admet-189	563	22	effectively	effectively	ADV
admet-189	563	23	treat	treat	VERB
admet-189	563	24	disease	disease	NOUN
admet-189	563	25	while	while	SCONJ
admet-189	563	26	staying	stay	VERB
admet-189	563	27	in	in	ADP
admet-189	563	28	the	the	DET
admet-189	563	29	safety	safety	NOUN
admet-189	563	30	range	range	NOUN
admet-189	563	31	and	and	CCONJ
admet-189	563	32	without	without	ADP
admet-189	563	33	inducing	induce	VERB
admet-189	563	34	adverse	adverse	ADJ
admet-189	563	35	effects	effect	NOUN
admet-189	563	36	[	[	X
admet-189	563	37	136	136	NUM
admet-189	563	38	]	]	PUNCT
admet-189	563	39	.	.	PUNCT
admet-189	564	1	comprehensive	comprehensive	ADJ
admet-189	564	2	testing	testing	NOUN
admet-189	564	3	for	for	ADP
admet-189	564	4	efficacy	efficacy	NOUN
admet-189	564	5	and	and	CCONJ
admet-189	564	6	toxicity	toxicity	NOUN
admet-189	564	7	must	must	AUX
admet-189	564	8	be	be	AUX
admet-189	564	9	performed	perform	VERB
admet-189	564	10	before	before	ADP
admet-189	564	11	the	the	DET
admet-189	564	12	introduction	introduction	NOUN
admet-189	564	13	of	of	ADP
admet-189	564	14	nanotechnology	nanotechnology	NOUN
admet-189	564	15	-	-	PUNCT
admet-189	564	16	based	base	VERB
admet-189	564	17	systems	system	NOUN
admet-189	564	18	into	into	ADP
admet-189	564	19	the	the	DET
admet-189	564	20	market	market	NOUN
admet-189	564	21	[	[	X
admet-189	564	22	136	136	NUM
admet-189	564	23	]	]	PUNCT
admet-189	564	24	.	.	PUNCT
admet-189	565	1	according	accord	VERB
admet-189	565	2	to	to	ADP
admet-189	565	3	the	the	DET
admet-189	565	4	royal	royal	ADJ
admet-189	565	5	society	society	NOUN
admet-189	565	6	/	/	SYM
admet-189	565	7	royal	royal	PROPN
admet-189	565	8	academy	academy	NOUN
admet-189	565	9	of	of	ADP
admet-189	565	10	engineering	engineering	PROPN
admet-189	565	11	report	report	NOUN
admet-189	565	12	(	(	PUNCT
admet-189	565	13	2004	2004	NUM
admet-189	565	14	)	)	PUNCT
admet-189	565	15	,	,	PUNCT
admet-189	565	16	carbon	carbon	NOUN
admet-189	565	17	nanotubes	nanotube	NOUN
admet-189	565	18	should	should	AUX
admet-189	565	19	be	be	AUX
admet-189	565	20	comprehensively	comprehensively	ADV
admet-189	565	21	tested	test	VERB
admet-189	565	22	as	as	ADP
admet-189	565	23	“	"	PUNCT
admet-189	565	24	new	new	ADJ
admet-189	565	25	substances	substance	NOUN
admet-189	565	26	”	"	PUNCT
admet-189	565	27	for	for	ADP
admet-189	565	28	their	their	PRON
admet-189	565	29	potential	potential	ADJ
admet-189	565	30	toxicities	toxicity	NOUN
admet-189	565	31	under	under	ADP
admet-189	565	32	uk	uk	PROPN
admet-189	565	33	and	and	CCONJ
admet-189	565	34	european	european	PROPN
admet-189	565	35	health	health	PROPN
admet-189	565	36	,	,	PUNCT
admet-189	565	37	safety	safety	NOUN
admet-189	565	38	and	and	CCONJ
admet-189	565	39	environment	environment	NOUN
admet-189	565	40	legislation	legislation	NOUN
admet-189	565	41	before	before	SCONJ
admet-189	565	42	they	they	PRON
admet-189	565	43	are	be	AUX
admet-189	565	44	introduced	introduce	VERB
admet-189	565	45	in	in	ADP
admet-189	565	46	the	the	DET
admet-189	565	47	market	market	NOUN
admet-189	565	48	[	[	X
admet-189	565	49	57	57	NUM
admet-189	565	50	]	]	PUNCT
admet-189	565	51	.	.	PUNCT
admet-189	566	1	however	however	ADV
admet-189	566	2	,	,	PUNCT
admet-189	566	3	each	each	DET
admet-189	566	4	nanoparticle	nanoparticle	NOUN
admet-189	566	5	is	be	AUX
admet-189	566	6	unique	unique	ADJ
admet-189	566	7	and	and	CCONJ
admet-189	566	8	it	it	PRON
admet-189	566	9	is	be	AUX
admet-189	566	10	necessary	necessary	ADJ
admet-189	566	11	to	to	PART
admet-189	566	12	understand	understand	VERB
admet-189	566	13	the	the	DET
admet-189	566	14	specific	specific	ADJ
admet-189	566	15	issues	issue	NOUN
admet-189	566	16	associated	associate	VERB
admet-189	566	17	with	with	ADP
admet-189	566	18	each	each	DET
admet-189	566	19	type	type	NOUN
admet-189	566	20	of	of	ADP
admet-189	566	21	nanoparticle	nanoparticle	NOUN
admet-189	566	22	for	for	ADP
admet-189	566	23	evaluation	evaluation	NOUN
admet-189	566	24	of	of	ADP
admet-189	566	25	toxicity	toxicity	NOUN
admet-189	566	26	issues	issue	NOUN
admet-189	566	27	.	.	PUNCT
admet-189	567	1	use	use	NOUN
admet-189	567	2	of	of	ADP
admet-189	567	3	green	green	ADJ
admet-189	567	4	chemistry	chemistry	NOUN
admet-189	567	5	,	,	PUNCT
admet-189	567	6	degradable	degradable	ADJ
admet-189	567	7	materials	material	NOUN
admet-189	567	8	,	,	PUNCT
admet-189	567	9	and	and	CCONJ
admet-189	567	10	regulatory	regulatory	ADJ
admet-189	567	11	approvals	approval	NOUN
admet-189	567	12	for	for	ADP
admet-189	567	13	nanotechnology	nanotechnology	NOUN
admet-189	567	14	-	-	PUNCT
admet-189	567	15	based	base	VERB
admet-189	567	16	products	product	NOUN
admet-189	567	17	are	be	AUX
admet-189	567	18	the	the	DET
admet-189	567	19	positive	positive	ADJ
admet-189	567	20	signals	signal	NOUN
admet-189	567	21	towards	towards	ADP
admet-189	567	22	an	an	DET
admet-189	567	23	optimistic	optimistic	ADJ
admet-189	567	24	future	future	NOUN
admet-189	567	25	with	with	ADP
admet-189	567	26	nanotechnology	nanotechnology	NOUN
admet-189	567	27	,	,	PUNCT
admet-189	567	28	the	the	DET
admet-189	567	29	effects	effect	NOUN
admet-189	567	30	of	of	ADP
admet-189	567	31	which	which	PRON
admet-189	567	32	can	can	AUX
admet-189	567	33	be	be	AUX
admet-189	567	34	of	of	ADP
admet-189	567	35	potential	potential	ADJ
admet-189	567	36	benefit	benefit	NOUN
admet-189	567	37	to	to	ADP
admet-189	567	38	patients	patient	NOUN
admet-189	567	39	with	with	ADP
admet-189	567	40	pd	pd	PROPN
admet-189	567	41	.	.	PROPN
admet-189	567	42	conclusions	conclusion	NOUN
admet-189	567	43	parkinson	parkinson	PROPN
admet-189	567	44	’s	’s	PART
admet-189	567	45	disease	disease	NOUN
admet-189	567	46	has	have	VERB
admet-189	567	47	a	a	DET
admet-189	567	48	huge	huge	ADJ
admet-189	567	49	impact	impact	NOUN
admet-189	567	50	on	on	ADP
admet-189	567	51	the	the	DET
admet-189	567	52	lives	life	NOUN
admet-189	567	53	of	of	ADP
admet-189	567	54	the	the	DET
admet-189	567	55	patients	patient	NOUN
admet-189	567	56	with	with	ADP
admet-189	567	57	tremendous	tremendous	ADJ
admet-189	567	58	socioeconomic	socioeconomic	ADJ
admet-189	567	59	effects	effect	NOUN
admet-189	567	60	.	.	PUNCT
admet-189	568	1	nanotechnology	nanotechnology	PROPN
admet-189	568	2	can	can	AUX
admet-189	568	3	serve	serve	VERB
admet-189	568	4	as	as	ADP
admet-189	568	5	a	a	DET
admet-189	568	6	viable	viable	ADJ
admet-189	568	7	alternative	alternative	NOUN
admet-189	568	8	to	to	ADP
admet-189	568	9	the	the	DET
admet-189	568	10	present	present	ADJ
admet-189	568	11	day	day	NOUN
admet-189	568	12	diagnosis	diagnosis	NOUN
admet-189	568	13	and	and	CCONJ
admet-189	568	14	treatment	treatment	NOUN
admet-189	568	15	of	of	ADP
admet-189	568	16	pd	pd	NOUN
admet-189	568	17	by	by	ADP
admet-189	568	18	providing	provide	VERB
admet-189	568	19	novel	novel	NOUN
admet-189	568	20	,	,	PUNCT
admet-189	568	21	affordable	affordable	ADJ
admet-189	568	22	and	and	CCONJ
admet-189	568	23	accessible	accessible	ADJ
admet-189	568	24	devices	device	NOUN
admet-189	568	25	.	.	PUNCT
admet-189	569	1	nanotechnological	nanotechnological	ADJ
admet-189	569	2	platforms	platform	NOUN
admet-189	569	3	are	be	AUX
admet-189	569	4	being	be	AUX
admet-189	569	5	increasingly	increasingly	ADV
admet-189	569	6	developed	develop	VERB
admet-189	569	7	with	with	ADP
admet-189	569	8	applications	application	NOUN
admet-189	569	9	in	in	ADP
admet-189	569	10	the	the	DET
admet-189	569	11	management	management	NOUN
admet-189	569	12	of	of	ADP
admet-189	569	13	pd	pd	PROPN
admet-189	569	14	.	.	PUNCT
admet-189	570	1	the	the	DET
admet-189	570	2	optimism	optimism	NOUN
admet-189	570	3	in	in	ADP
admet-189	570	4	the	the	DET
admet-189	570	5	translation	translation	NOUN
admet-189	570	6	of	of	ADP
admet-189	570	7	these	these	DET
admet-189	570	8	technologies	technology	NOUN
admet-189	570	9	from	from	ADP
admet-189	570	10	labs	lab	NOUN
admet-189	570	11	to	to	ADP
admet-189	570	12	bedside	bedside	NOUN
admet-189	570	13	can	can	AUX
admet-189	570	14	be	be	AUX
admet-189	570	15	seen	see	VERB
admet-189	570	16	with	with	ADP
admet-189	570	17	increasing	increase	VERB
admet-189	570	18	interest	interest	NOUN
admet-189	570	19	by	by	ADP
admet-189	570	20	grant	grant	NOUN
admet-189	570	21	agencies	agency	NOUN
admet-189	570	22	,	,	PUNCT
admet-189	570	23	companies	company	NOUN
admet-189	570	24	and	and	CCONJ
admet-189	570	25	physicians	physician	NOUN
admet-189	570	26	towards	towards	ADP
admet-189	570	27	their	their	PRON
admet-189	570	28	development	development	NOUN
admet-189	570	29	.	.	PUNCT
admet-189	571	1	the	the	DET
admet-189	571	2	tremendous	tremendous	ADJ
admet-189	571	3	potential	potential	NOUN
admet-189	571	4	to	to	AUX
admet-189	571	5	tweak	tweak	VERB
admet-189	571	6	nanoparticles	nanoparticle	NOUN
admet-189	571	7	in	in	ADP
admet-189	571	8	the	the	DET
admet-189	571	9	nanoscale	nanoscale	NOUN
admet-189	571	10	can	can	AUX
admet-189	571	11	prove	prove	VERB
admet-189	571	12	to	to	PART
admet-189	571	13	be	be	AUX
admet-189	571	14	of	of	ADP
admet-189	571	15	great	great	ADJ
admet-189	571	16	help	help	NOUN
admet-189	571	17	in	in	ADP
admet-189	571	18	the	the	DET
admet-189	571	19	fight	fight	NOUN
admet-189	571	20	against	against	ADP
admet-189	571	21	parkinson	parkinson	NOUN
admet-189	571	22	’s	’s	PART
admet-189	571	23	disease	disease	NOUN
admet-189	571	24	.	.	PUNCT
admet-189	572	1	references	reference	NOUN
admet-189	572	2	[	[	X
admet-189	572	3	1	1	NUM
admet-189	572	4	]	]	X
admet-189	572	5	d.	d.	PROPN
admet-189	572	6	longo	longo	PROPN
admet-189	572	7	,	,	PUNCT
admet-189	572	8	a.	a.	NOUN
admet-189	572	9	fauci	fauci	PROPN
admet-189	572	10	,	,	PUNCT
admet-189	572	11	d.	d.	PROPN
admet-189	572	12	kasper	kasper	PROPN
admet-189	572	13	,	,	PUNCT
admet-189	572	14	s.	s.	PROPN
admet-189	572	15	hauser	hauser	PROPN
admet-189	572	16	,	,	PUNCT
admet-189	572	17	j.	j.	PROPN
admet-189	572	18	jameson	jameson	PROPN
admet-189	572	19	,	,	PUNCT
admet-189	572	20	j.	j.	PROPN
admet-189	572	21	loscalzo	loscalzo	PROPN
admet-189	572	22	,	,	PUNCT
admet-189	572	23	harrison	harrison	PROPN
admet-189	572	24	's	's	PART
admet-189	572	25	principles	principle	NOUN
admet-189	572	26	of	of	ADP
admet-189	572	27	internal	internal	ADJ
admet-189	572	28	medicine	medicine	NOUN
admet-189	572	29	,	,	PUNCT
admet-189	572	30	mcgraw	mcgraw	NOUN
admet-189	572	31	-	-	PUNCT
admet-189	572	32	hill	hill	NOUN
admet-189	572	33	education	education	NOUN
admet-189	572	34	,	,	PUNCT
admet-189	572	35	2011	2011	NUM
admet-189	572	36	.	.	PUNCT
admet-189	573	1	[	[	X
admet-189	573	2	2	2	X
admet-189	573	3	]	]	PUNCT
admet-189	573	4	t.	t.	NOUN
admet-189	573	5	pringsheim	pringsheim	PROPN
admet-189	573	6	,	,	PUNCT
admet-189	573	7	n.	n.	PROPN
admet-189	573	8	jette	jette	PROPN
admet-189	573	9	,	,	PUNCT
admet-189	573	10	a.	a.	NOUN
admet-189	573	11	frolkis	frolkis	PROPN
admet-189	573	12	,	,	PUNCT
admet-189	573	13	t.d.l	t.d.l	NOUN
admet-189	573	14	.	.	PUNCT
admet-189	574	1	steeves	steeve	NOUN
admet-189	574	2	,	,	PUNCT
admet-189	574	3	mov	mov	NOUN
admet-189	574	4	.	.	PUNCT
admet-189	574	5	disord	disord	PROPN
admet-189	574	6	.	.	PUNCT
admet-189	575	1	29	29	NUM
admet-189	575	2	(	(	PUNCT
admet-189	575	3	2014	2014	NUM
admet-189	575	4	)	)	PUNCT
admet-189	575	5	1583	1583	NUM
admet-189	575	6	-	-	SYM
admet-189	575	7	1590	1590	NUM
admet-189	575	8	.	.	PUNCT
admet-189	576	1	[	[	X
admet-189	576	2	3	3	X
admet-189	576	3	]	]	PUNCT
admet-189	576	4	world	world	PROPN
admet-189	576	5	health	health	NOUN
admet-189	576	6	organization	organization	NOUN
admet-189	576	7	,	,	PUNCT
admet-189	576	8	neurological	neurological	ADJ
admet-189	576	9	disorders	disorder	NOUN
admet-189	576	10	:	:	PUNCT
admet-189	576	11	public	public	ADJ
admet-189	576	12	health	health	NOUN
admet-189	576	13	challenges	challenge	NOUN
admet-189	576	14	,	,	PUNCT
admet-189	576	15	world	world	NOUN
admet-189	576	16	health	health	NOUN
admet-189	576	17	organization	organization	PROPN
admet-189	576	18	,	,	PUNCT
admet-189	576	19	geneva	geneva	PROPN
admet-189	576	20	,	,	PUNCT
admet-189	576	21	switzerland	switzerland	PROPN
admet-189	576	22	,	,	PUNCT
admet-189	576	23	2006	2006	NUM
admet-189	576	24	.	.	PUNCT
admet-189	577	1	[	[	X
admet-189	577	2	4	4	NUM
admet-189	577	3	]	]	X
admet-189	577	4	s.l	s.l	PROPN
admet-189	577	5	.	.	PROPN
admet-189	577	6	kowal	kowal	PROPN
admet-189	577	7	,	,	PUNCT
admet-189	577	8	t.m	t.m	PROPN
admet-189	577	9	.	.	PROPN
admet-189	577	10	dall	dall	PROPN
admet-189	577	11	,	,	PUNCT
admet-189	577	12	r.	r.	PROPN
admet-189	577	13	chakrabarti	chakrabarti	PROPN
admet-189	577	14	,	,	PUNCT
admet-189	577	15	m.v	m.v	PROPN
admet-189	577	16	.	.	PROPN
admet-189	577	17	storm	storm	PROPN
admet-189	577	18	,	,	PUNCT
admet-189	577	19	a.	a.	NOUN
admet-189	577	20	jain	jain	PROPN
admet-189	577	21	,	,	PUNCT
admet-189	577	22	mov	mov	PROPN
admet-189	577	23	.	.	PUNCT
admet-189	577	24	disord	disord	PROPN
admet-189	577	25	.	.	PUNCT
admet-189	578	1	28	28	NUM
admet-189	578	2	(	(	PUNCT
admet-189	578	3	2013	2013	NUM
admet-189	578	4	)	)	PUNCT
admet-189	578	5	311	311	NUM
admet-189	578	6	-	-	SYM
admet-189	578	7	318	318	NUM
admet-189	578	8	.	.	PUNCT
admet-189	579	1	[	[	X
admet-189	579	2	5	5	NUM
admet-189	579	3	]	]	PUNCT
admet-189	579	4	m.	m.	NOUN
admet-189	579	5	ragothaman	ragothaman	PROPN
admet-189	579	6	,	,	PUNCT
admet-189	579	7	s.t	s.t	PROPN
admet-189	579	8	.	.	PROPN
admet-189	579	9	govindappa	govindappa	PROPN
admet-189	579	10	,	,	PUNCT
admet-189	579	11	r.	r.	PROPN
admet-189	579	12	rattihalli	rattihalli	PROPN
admet-189	579	13	,	,	PUNCT
admet-189	579	14	d.k	d.k	PROPN
admet-189	579	15	.	.	PROPN
admet-189	579	16	subbakrishna	subbakrishna	PROPN
admet-189	579	17	,	,	PUNCT
admet-189	579	18	u.b	u.b	PROPN
admet-189	579	19	.	.	PROPN
admet-189	579	20	muthane	muthane	PROPN
admet-189	579	21	,	,	PUNCT
admet-189	579	22	mov	mov	NOUN
admet-189	579	23	disord	disord	NOUN
admet-189	579	24	21	21	NUM
admet-189	579	25	(	(	PUNCT
admet-189	579	26	2006	2006	NUM
admet-189	579	27	)	)	PUNCT
admet-189	579	28	1755	1755	NUM
admet-189	579	29	-	-	SYM
admet-189	579	30	1758	1758	NUM
admet-189	579	31	.	.	PUNCT
admet-189	580	1	[	[	X
admet-189	580	2	6	6	NUM
admet-189	580	3	]	]	X
admet-189	580	4	c.g	c.g	PROPN
admet-189	580	5	.	.	PROPN
admet-189	580	6	goetz	goetz	PROPN
admet-189	580	7	,	,	PUNCT
admet-189	580	8	mov	mov	PROPN
admet-189	580	9	.	.	PUNCT
admet-189	580	10	disord	disord	PROPN
admet-189	580	11	.	.	PUNCT
admet-189	581	1	1	1	NUM
admet-189	581	2	(	(	PUNCT
admet-189	581	3	1986	1986	NUM
admet-189	581	4	)	)	PUNCT
admet-189	581	5	27	27	NUM
admet-189	581	6	-	-	SYM
admet-189	581	7	32	32	NUM
admet-189	581	8	.	.	PUNCT
admet-189	582	1	admet	admet	PROPN
admet-189	582	2	&	&	CCONJ
admet-189	582	3	dmpk	dmpk	PROPN
admet-189	582	4	3(3	3(3	NUM
admet-189	582	5	)	)	PUNCT
admet-189	582	6	(	(	PUNCT
admet-189	582	7	2015	2015	NUM
admet-189	582	8	)	)	PUNCT
admet-189	582	9	155	155	NUM
admet-189	582	10	-	-	SYM
admet-189	582	11	181	181	NUM
admet-189	582	12	nanotechnology	nanotechnology	NOUN
admet-189	582	13	platforms	platform	NOUN
admet-189	582	14	in	in	ADP
admet-189	582	15	parkinson	parkinson	NOUN
admet-189	582	16	’s	’s	PART
admet-189	582	17	disease	disease	NOUN
admet-189	582	18	doi	doi	NOUN
admet-189	582	19	:	:	PUNCT
admet-189	582	20	10.5599	10.5599	NUM
admet-189	582	21	/	/	SYM
admet-189	582	22	admet.3.3.189	admet.3.3.189	ADP
admet-189	582	23	177	177	NUM
admet-189	582	24	[	[	X
admet-189	582	25	7	7	NUM
admet-189	582	26	]	]	X
admet-189	582	27	d.	d.	PROPN
admet-189	582	28	berg	berg	PROPN
admet-189	582	29	,	,	PUNCT
admet-189	582	30	a.e	a.e	PROPN
admet-189	582	31	.	.	PROPN
admet-189	582	32	lang	lang	PROPN
admet-189	582	33	,	,	PUNCT
admet-189	582	34	r.b	r.b	PROPN
admet-189	582	35	.	.	PROPN
admet-189	582	36	postuma	postuma	PROPN
admet-189	582	37	,	,	PUNCT
admet-189	582	38	w.	w.	PROPN
admet-189	582	39	maetzler	maetzler	NOUN
admet-189	582	40	,	,	PUNCT
admet-189	582	41	g.	g.	PROPN
admet-189	582	42	deuschl	deuschl	PROPN
admet-189	582	43	,	,	PUNCT
admet-189	582	44	t.	t.	NOUN
admet-189	582	45	gasser	gasser	NOUN
admet-189	582	46	,	,	PUNCT
admet-189	582	47	a.	a.	NOUN
admet-189	582	48	siderowf	siderowf	NOUN
admet-189	582	49	,	,	PUNCT
admet-189	582	50	a.h	a.h	PROPN
admet-189	582	51	.	.	PROPN
admet-189	582	52	schapira	schapira	PROPN
admet-189	582	53	,	,	PUNCT
admet-189	582	54	w.	w.	PROPN
admet-189	582	55	oertel	oertel	PROPN
admet-189	582	56	,	,	PUNCT
admet-189	582	57	j.a	j.a	PROPN
admet-189	582	58	.	.	PROPN
admet-189	582	59	obeso	obeso	NOUN
admet-189	582	60	,	,	PUNCT
admet-189	582	61	c.w	c.w	PROPN
admet-189	582	62	.	.	PROPN
admet-189	582	63	olanow	olanow	PROPN
admet-189	582	64	,	,	PUNCT
admet-189	582	65	w.	w.	PROPN
admet-189	582	66	poewe	poewe	PROPN
admet-189	582	67	,	,	PUNCT
admet-189	582	68	m.	m.	NOUN
admet-189	582	69	stern	stern	NOUN
admet-189	582	70	,	,	PUNCT
admet-189	582	71	lancet	lancet	NOUN
admet-189	582	72	neurol	neurol	NOUN
admet-189	582	73	.	.	PUNCT
admet-189	583	1	12	12	NUM
admet-189	583	2	(	(	PUNCT
admet-189	583	3	2013	2013	NUM
admet-189	583	4	)	)	PUNCT
admet-189	583	5	514	514	NUM
admet-189	583	6	-	-	SYM
admet-189	583	7	524	524	NUM
admet-189	583	8	.	.	PUNCT
admet-189	584	1	[	[	X
admet-189	584	2	8	8	NUM
admet-189	584	3	]	]	X
admet-189	584	4	l.m	l.m	PROPN
admet-189	584	5	.	.	PROPN
admet-189	584	6	de	de	PROPN
admet-189	584	7	lau	lau	PROPN
admet-189	584	8	,	,	PUNCT
admet-189	584	9	m.m	m.m	PROPN
admet-189	584	10	.	.	PROPN
admet-189	584	11	breteler	breteler	PROPN
admet-189	584	12	,	,	PUNCT
admet-189	584	13	lancet	lancet	NOUN
admet-189	584	14	neurol	neurol	NOUN
admet-189	584	15	.	.	PUNCT
admet-189	585	1	5	5	NUM
admet-189	585	2	(	(	PUNCT
admet-189	585	3	2006	2006	NUM
admet-189	585	4	)	)	PUNCT
admet-189	585	5	525	525	NUM
admet-189	585	6	-	-	SYM
admet-189	585	7	535	535	NUM
admet-189	585	8	.	.	PUNCT
admet-189	586	1	[	[	X
admet-189	586	2	9	9	NUM
admet-189	586	3	]	]	X
admet-189	586	4	s.k	s.k	PROPN
admet-189	586	5	.	.	PROPN
admet-189	586	6	van	van	PROPN
admet-189	586	7	den	den	PROPN
admet-189	586	8	eeden	eeden	PROPN
admet-189	586	9	,	,	PUNCT
admet-189	586	10	c.m	c.m	PROPN
admet-189	586	11	.	.	PROPN
admet-189	586	12	tanner	tanner	NOUN
admet-189	586	13	,	,	PUNCT
admet-189	586	14	a.l	a.l	PROPN
admet-189	586	15	.	.	PROPN
admet-189	586	16	bernstein	bernstein	PROPN
admet-189	586	17	,	,	PUNCT
admet-189	586	18	r.d	r.d	PROPN
admet-189	586	19	.	.	PROPN
admet-189	586	20	fross	fross	PROPN
admet-189	586	21	,	,	PUNCT
admet-189	586	22	a.	a.	NOUN
admet-189	586	23	leimpeter	leimpeter	NOUN
admet-189	586	24	,	,	PUNCT
admet-189	586	25	d.a	d.a	PROPN
admet-189	586	26	.	.	PROPN
admet-189	586	27	bloch	bloch	PROPN
admet-189	586	28	,	,	PUNCT
admet-189	586	29	l.m	l.m	PROPN
admet-189	586	30	.	.	PROPN
admet-189	586	31	nelson	nelson	PROPN
admet-189	586	32	,	,	PUNCT
admet-189	586	33	am	be	AUX
admet-189	586	34	.	.	PUNCT
admet-189	587	1	j.	j.	PROPN
admet-189	587	2	epidemiol	epidemiol	PROPN
admet-189	587	3	.	.	PROPN
admet-189	588	1	157	157	NUM
admet-189	588	2	(	(	PUNCT
admet-189	588	3	2003	2003	NUM
admet-189	588	4	)	)	PUNCT
admet-189	588	5	1015	1015	NUM
admet-189	588	6	-	-	SYM
admet-189	588	7	1022	1022	NUM
admet-189	588	8	.	.	PUNCT
admet-189	589	1	[	[	X
admet-189	589	2	10	10	NUM
admet-189	589	3	]	]	X
admet-189	589	4	a.	a.	NOUN
admet-189	589	5	benazzouz	benazzouz	PROPN
admet-189	589	6	,	,	PUNCT
admet-189	589	7	o.	o.	NOUN
admet-189	589	8	mamad	mamad	NOUN
admet-189	589	9	,	,	PUNCT
admet-189	589	10	p.	p.	PROPN
admet-189	589	11	abedi	abedi	PROPN
admet-189	589	12	,	,	PUNCT
admet-189	589	13	r.	r.	PROPN
admet-189	589	14	bouali	bouali	PROPN
admet-189	589	15	-	-	PUNCT
admet-189	589	16	benazzouz	benazzouz	PROPN
admet-189	589	17	,	,	PUNCT
admet-189	589	18	j.	j.	PROPN
admet-189	589	19	chetrit	chetrit	PROPN
admet-189	589	20	,	,	PUNCT
admet-189	589	21	front	front	NOUN
admet-189	589	22	.	.	PUNCT
admet-189	590	1	aging	age	VERB
admet-189	590	2	neurosci	neurosci	NOUN
admet-189	590	3	.	.	PUNCT
admet-189	591	1	6	6	NUM
admet-189	591	2	(	(	PUNCT
admet-189	591	3	2014	2014	NUM
admet-189	591	4	)	)	PUNCT
admet-189	591	5	87	87	NUM
admet-189	591	6	.	.	PUNCT
admet-189	592	1	[	[	X
admet-189	592	2	11	11	NUM
admet-189	592	3	]	]	PUNCT
admet-189	592	4	a.m.	a.m.	NOUN
admet-189	592	5	bonnet	bonnet	PROPN
admet-189	592	6	,	,	PUNCT
admet-189	592	7	j.l	j.l	PROPN
admet-189	592	8	.	.	PROPN
admet-189	592	9	houeto	houeto	PROPN
admet-189	592	10	,	,	PUNCT
admet-189	592	11	biomed	biome	VERB
admet-189	592	12	.	.	PUNCT
admet-189	593	1	pharmacother	pharmacother	ADJ
admet-189	593	2	.	.	PUNCT
admet-189	594	1	53	53	NUM
admet-189	594	2	(	(	PUNCT
admet-189	594	3	1999	1999	NUM
admet-189	594	4	)	)	PUNCT
admet-189	594	5	117	117	NUM
admet-189	594	6	-	-	SYM
admet-189	594	7	121	121	NUM
admet-189	594	8	.	.	PUNCT
admet-189	595	1	[	[	X
admet-189	595	2	12	12	NUM
admet-189	595	3	]	]	PUNCT
admet-189	595	4	m.	m.	PROPN
admet-189	595	5	storch	storch	PROPN
admet-189	595	6	,	,	PUNCT
admet-189	595	7	a.	a.	PROPN
admet-189	595	8	storch	storch	PROPN
admet-189	595	9	,	,	PUNCT
admet-189	595	10	m.a	m.a	PROPN
admet-189	595	11	.	.	PROPN
admet-189	595	12	collins	collins	PROPN
admet-189	595	13	,	,	PUNCT
admet-189	595	14	neurotoxic	neurotoxic	ADJ
admet-189	595	15	factors	factor	NOUN
admet-189	595	16	in	in	ADP
admet-189	595	17	parkinson	parkinson	NOUN
admet-189	595	18	’s	’s	PART
admet-189	595	19	disease	disease	NOUN
admet-189	595	20	,	,	PUNCT
admet-189	595	21	related	related	ADJ
admet-189	595	22	disorders	disorder	NOUN
admet-189	595	23	,	,	PUNCT
admet-189	595	24	springer	springer	NOUN
admet-189	595	25	us	we	PRON
admet-189	595	26	,	,	PUNCT
admet-189	595	27	2001	2001	NUM
admet-189	595	28	.	.	PUNCT
admet-189	596	1	[	[	X
admet-189	596	2	13	13	NUM
admet-189	596	3	]	]	X
admet-189	596	4	d.c	d.c	PROPN
admet-189	596	5	.	.	PROPN
admet-189	596	6	german	german	PROPN
admet-189	596	7	,	,	PUNCT
admet-189	596	8	k.f	k.f	PROPN
admet-189	596	9	.	.	PROPN
admet-189	596	10	manaye	manaye	PROPN
admet-189	596	11	,	,	PUNCT
admet-189	596	12	c.l	c.l	PROPN
admet-189	596	13	.	.	PROPN
admet-189	596	14	white	white	ADJ
admet-189	596	15	,	,	PUNCT
admet-189	596	16	3rd	3rd	NOUN
admet-189	596	17	,	,	PUNCT
admet-189	596	18	d.j	d.j	PROPN
admet-189	596	19	.	.	PROPN
admet-189	596	20	woodward	woodward	PROPN
admet-189	596	21	,	,	PUNCT
admet-189	596	22	d.d	d.d	PROPN
admet-189	596	23	.	.	PROPN
admet-189	596	24	mcintire	mcintire	PROPN
admet-189	596	25	,	,	PUNCT
admet-189	596	26	w.k	w.k	PROPN
admet-189	596	27	.	.	PROPN
admet-189	596	28	smith	smith	PROPN
admet-189	596	29	,	,	PUNCT
admet-189	596	30	r.n	r.n	PROPN
admet-189	596	31	.	.	PROPN
admet-189	596	32	kalaria	kalaria	PROPN
admet-189	596	33	,	,	PUNCT
admet-189	596	34	d.m	d.m	PROPN
admet-189	596	35	.	.	PROPN
admet-189	596	36	mann	mann	PROPN
admet-189	596	37	,	,	PUNCT
admet-189	596	38	ann	ann	PROPN
admet-189	596	39	.	.	PUNCT
admet-189	597	1	neurol	neurol	PROPN
admet-189	597	2	.	.	PUNCT
admet-189	598	1	32	32	NUM
admet-189	598	2	(	(	PUNCT
admet-189	598	3	1992	1992	NUM
admet-189	598	4	)	)	PUNCT
admet-189	598	5	667	667	NUM
admet-189	598	6	-	-	SYM
admet-189	598	7	676	676	NUM
admet-189	598	8	.	.	PUNCT
admet-189	599	1	[	[	X
admet-189	599	2	14	14	NUM
admet-189	599	3	]	]	X
admet-189	599	4	h.m	h.m	PROPN
admet-189	599	5	.	.	PROPN
admet-189	599	6	van	van	PROPN
admet-189	599	7	praag	praag	PROPN
admet-189	599	8	,	,	PUNCT
admet-189	599	9	s.	s.	PROPN
admet-189	599	10	de	de	PROPN
admet-189	599	11	haan	haan	PROPN
admet-189	599	12	,	,	PUNCT
admet-189	599	13	psychiatry	psychiatry	NOUN
admet-189	599	14	res	re	NOUN
admet-189	599	15	.	.	PROPN
admet-189	599	16	1	1	NUM
admet-189	599	17	(	(	PUNCT
admet-189	599	18	1979	1979	NUM
admet-189	599	19	)	)	PUNCT
admet-189	599	20	219	219	NUM
admet-189	599	21	-	-	SYM
admet-189	599	22	224	224	NUM
admet-189	599	23	.	.	PUNCT
admet-189	600	1	[	[	X
admet-189	600	2	15	15	NUM
admet-189	600	3	]	]	X
admet-189	600	4	j.t	j.t	PROPN
admet-189	600	5	.	.	PROPN
admet-189	600	6	greenamyre	greenamyre	PROPN
admet-189	600	7	,	,	PUNCT
admet-189	600	8	c.f	c.f	PROPN
admet-189	600	9	.	.	PROPN
admet-189	600	10	o'brien	o'brien	PROPN
admet-189	600	11	,	,	PUNCT
admet-189	600	12	arch	arch	NOUN
admet-189	600	13	.	.	PUNCT
admet-189	601	1	neurol	neurol	NOUN
admet-189	601	2	.	.	PUNCT
admet-189	602	1	48	48	NUM
admet-189	602	2	(	(	PUNCT
admet-189	602	3	1991	1991	NUM
admet-189	602	4	)	)	PUNCT
admet-189	602	5	977	977	NUM
admet-189	602	6	-	-	SYM
admet-189	602	7	981	981	NUM
admet-189	602	8	.	.	PUNCT
admet-189	603	1	[	[	X
admet-189	603	2	16	16	NUM
admet-189	603	3	]	]	PUNCT
admet-189	603	4	s.	s.	PROPN
admet-189	603	5	haber	haber	PROPN
admet-189	603	6	,	,	PUNCT
admet-189	603	7	s.j	s.j	PROPN
admet-189	603	8	.	.	PROPN
admet-189	603	9	watson	watson	PROPN
admet-189	603	10	,	,	PUNCT
admet-189	603	11	neuroscience	neuroscience	NOUN
admet-189	603	12	14	14	NUM
admet-189	603	13	(	(	PUNCT
admet-189	603	14	1985	1985	NUM
admet-189	603	15	)	)	PUNCT
admet-189	603	16	1011	1011	NUM
admet-189	603	17	-	-	SYM
admet-189	603	18	1024	1024	NUM
admet-189	603	19	.	.	PUNCT
admet-189	604	1	[	[	X
admet-189	604	2	17	17	NUM
admet-189	604	3	]	]	X
admet-189	604	4	c.w	c.w	PROPN
admet-189	604	5	.	.	PROPN
admet-189	604	6	olanow	olanow	PROPN
admet-189	604	7	,	,	PUNCT
admet-189	604	8	w.g	w.g	PROPN
admet-189	604	9	.	.	PROPN
admet-189	604	10	tatton	tatton	PROPN
admet-189	604	11	,	,	PUNCT
admet-189	604	12	annu	annu	PROPN
admet-189	604	13	.	.	PUNCT
admet-189	604	14	rev	rev	PROPN
admet-189	604	15	.	.	PROPN
admet-189	604	16	neurosci	neurosci	PROPN
admet-189	604	17	.	.	PUNCT
admet-189	605	1	22	22	NUM
admet-189	605	2	(	(	PUNCT
admet-189	605	3	1999	1999	NUM
admet-189	605	4	)	)	PUNCT
admet-189	605	5	123	123	NUM
admet-189	605	6	-	-	SYM
admet-189	605	7	144	144	NUM
admet-189	605	8	.	.	PUNCT
admet-189	606	1	[	[	X
admet-189	606	2	18	18	NUM
admet-189	606	3	]	]	X
admet-189	606	4	z.i	z.i	PROPN
admet-189	606	5	.	.	PUNCT
admet-189	606	6	alam	alam	PROPN
admet-189	606	7	,	,	PUNCT
admet-189	606	8	a.	a.	PROPN
admet-189	606	9	jenner	jenner	PROPN
admet-189	606	10	,	,	PUNCT
admet-189	606	11	s.e	s.e	PROPN
admet-189	606	12	.	.	PROPN
admet-189	606	13	daniel	daniel	PROPN
admet-189	606	14	,	,	PUNCT
admet-189	606	15	a.j	a.j	PROPN
admet-189	606	16	.	.	PROPN
admet-189	606	17	lees	lee	NOUN
admet-189	606	18	,	,	PUNCT
admet-189	606	19	n.	n.	PROPN
admet-189	606	20	cairns	cairns	PROPN
admet-189	606	21	,	,	PUNCT
admet-189	606	22	c.d	c.d	PROPN
admet-189	606	23	.	.	PUNCT
admet-189	606	24	marsden	marsden	PROPN
admet-189	606	25	,	,	PUNCT
admet-189	606	26	p.	p.	PROPN
admet-189	606	27	jenner	jenner	PROPN
admet-189	606	28	,	,	PUNCT
admet-189	606	29	b.	b.	PROPN
admet-189	606	30	halliwell	halliwell	PROPN
admet-189	606	31	,	,	PUNCT
admet-189	606	32	j.	j.	PROPN
admet-189	606	33	neurochem	neurochem	PROPN
admet-189	606	34	.	.	PUNCT
admet-189	607	1	69	69	NUM
admet-189	607	2	(	(	PUNCT
admet-189	607	3	1997	1997	NUM
admet-189	607	4	)	)	PUNCT
admet-189	607	5	1196	1196	NUM
admet-189	607	6	-	-	SYM
admet-189	607	7	1203	1203	NUM
admet-189	607	8	.	.	PUNCT
admet-189	608	1	[	[	X
admet-189	608	2	19	19	NUM
admet-189	608	3	]	]	X
admet-189	608	4	a.h.v	a.h.v	PROPN
admet-189	608	5	.	.	PROPN
admet-189	608	6	schapira	schapira	PROPN
admet-189	608	7	,	,	PUNCT
admet-189	608	8	j.m	j.m	PROPN
admet-189	608	9	.	.	PROPN
admet-189	608	10	cooper	cooper	PROPN
admet-189	608	11	,	,	PUNCT
admet-189	608	12	d.	d.	PROPN
admet-189	608	13	dexter	dexter	PROPN
admet-189	608	14	,	,	PUNCT
admet-189	608	15	j.b	j.b	PROPN
admet-189	608	16	.	.	PROPN
admet-189	608	17	clark	clark	PROPN
admet-189	608	18	,	,	PUNCT
admet-189	608	19	p.	p.	PROPN
admet-189	608	20	jenner	jenner	PROPN
admet-189	608	21	,	,	PUNCT
admet-189	608	22	c.d	c.d	PROPN
admet-189	608	23	.	.	PROPN
admet-189	608	24	marsden	marsden	PROPN
admet-189	608	25	,	,	PUNCT
admet-189	608	26	j.	j.	PROPN
admet-189	608	27	neurochem	neurochem	PROPN
admet-189	608	28	.	.	PUNCT
admet-189	609	1	54	54	NUM
admet-189	609	2	(	(	PUNCT
admet-189	609	3	1990	1990	NUM
admet-189	609	4	)	)	PUNCT
admet-189	609	5	823	823	NUM
admet-189	609	6	-	-	SYM
admet-189	609	7	827	827	NUM
admet-189	609	8	.	.	PUNCT
admet-189	610	1	[	[	X
admet-189	610	2	20	20	NUM
admet-189	610	3	]	]	X
admet-189	610	4	d.j	d.j	PROPN
admet-189	610	5	.	.	PROPN
admet-189	610	6	moore	moore	PROPN
admet-189	610	7	,	,	PUNCT
admet-189	610	8	a.b	a.b	PROPN
admet-189	610	9	.	.	PROPN
admet-189	610	10	west	west	PROPN
admet-189	610	11	,	,	PUNCT
admet-189	610	12	v.l	v.l	PROPN
admet-189	610	13	.	.	PROPN
admet-189	610	14	dawson	dawson	PROPN
admet-189	610	15	,	,	PUNCT
admet-189	610	16	t.m	t.m	PROPN
admet-189	610	17	.	.	PROPN
admet-189	610	18	dawson	dawson	PROPN
admet-189	610	19	,	,	PUNCT
admet-189	610	20	annu	annu	PROPN
admet-189	610	21	.	.	PUNCT
admet-189	610	22	rev	rev	PROPN
admet-189	610	23	.	.	PROPN
admet-189	610	24	neurosci	neurosci	PROPN
admet-189	610	25	.	.	PUNCT
admet-189	611	1	28	28	NUM
admet-189	611	2	(	(	PUNCT
admet-189	611	3	2005	2005	NUM
admet-189	611	4	)	)	PUNCT
admet-189	611	5	57	57	NUM
admet-189	611	6	-	-	SYM
admet-189	611	7	87	87	NUM
admet-189	611	8	.	.	PUNCT
admet-189	612	1	[	[	X
admet-189	612	2	21	21	NUM
admet-189	612	3	]	]	X
admet-189	612	4	z.h	z.h	PROPN
admet-189	612	5	.	.	PROPN
admet-189	612	6	sheng	sheng	PROPN
admet-189	612	7	,	,	PUNCT
admet-189	612	8	q.	q.	PROPN
admet-189	612	9	cai	cai	PROPN
admet-189	612	10	,	,	PUNCT
admet-189	612	11	nat	nat	PROPN
admet-189	612	12	.	.	PUNCT
admet-189	613	1	rev	rev	PROPN
admet-189	613	2	.	.	PROPN
admet-189	613	3	neurosci	neurosci	PROPN
admet-189	613	4	.	.	PUNCT
admet-189	614	1	13	13	NUM
admet-189	614	2	(	(	PUNCT
admet-189	614	3	2012	2012	NUM
admet-189	614	4	)	)	PUNCT
admet-189	614	5	77	77	NUM
admet-189	614	6	-	-	SYM
admet-189	614	7	93	93	NUM
admet-189	614	8	.	.	PUNCT
admet-189	615	1	[	[	X
admet-189	615	2	22	22	NUM
admet-189	615	3	]	]	PUNCT
admet-189	615	4	a.	a.	NOUN
admet-189	615	5	thaler	thaler	PROPN
admet-189	615	6	,	,	PUNCT
admet-189	615	7	e.	e.	PROPN
admet-189	615	8	ash	ash	PROPN
admet-189	615	9	,	,	PUNCT
admet-189	615	10	z.	z.	PROPN
admet-189	615	11	gan	gan	PROPN
admet-189	615	12	-	-	PUNCT
admet-189	615	13	or	or	CCONJ
admet-189	615	14	,	,	PUNCT
admet-189	615	15	a.	a.	PROPN
admet-189	615	16	orr	orr	PROPN
admet-189	615	17	-	-	PUNCT
admet-189	615	18	urtreger	urtreger	NOUN
admet-189	615	19	,	,	PUNCT
admet-189	615	20	n.	n.	NOUN
admet-189	615	21	giladi	giladi	PROPN
admet-189	615	22	,	,	PUNCT
admet-189	615	23	j.	j.	PROPN
admet-189	615	24	neural	neural	PROPN
admet-189	615	25	.	.	PUNCT
admet-189	616	1	transm	transm	PROPN
admet-189	616	2	.	.	PUNCT
admet-189	617	1	116	116	NUM
admet-189	617	2	(	(	PUNCT
admet-189	617	3	2009	2009	NUM
admet-189	617	4	)	)	PUNCT
admet-189	617	5	1473	1473	NUM
admet-189	617	6	-	-	SYM
admet-189	617	7	1482	1482	NUM
admet-189	617	8	.	.	PUNCT
admet-189	618	1	[	[	X
admet-189	618	2	23	23	NUM
admet-189	618	3	]	]	SYM
admet-189	618	4	a.b	a.b	PROPN
admet-189	618	5	.	.	PROPN
admet-189	618	6	singleton	singleton	PROPN
admet-189	618	7	,	,	PUNCT
admet-189	618	8	m.j	m.j	PROPN
admet-189	618	9	.	.	PROPN
admet-189	618	10	farrer	farrer	PROPN
admet-189	618	11	,	,	PUNCT
admet-189	618	12	v.	v.	CCONJ
admet-189	618	13	bonifati	bonifati	PROPN
admet-189	618	14	,	,	PUNCT
admet-189	618	15	mov	mov	NOUN
admet-189	618	16	.	.	PUNCT
admet-189	618	17	disord	disord	PROPN
admet-189	618	18	.	.	PUNCT
admet-189	619	1	28	28	NUM
admet-189	619	2	(	(	PUNCT
admet-189	619	3	2013	2013	NUM
admet-189	619	4	)	)	PUNCT
admet-189	619	5	14	14	NUM
admet-189	619	6	-	-	SYM
admet-189	619	7	23	23	NUM
admet-189	619	8	.	.	PUNCT
admet-189	620	1	[	[	X
admet-189	620	2	24	24	NUM
admet-189	620	3	]	]	X
admet-189	620	4	l.j	l.j	PROPN
admet-189	620	5	.	.	PROPN
admet-189	620	6	ozelius	ozelius	PROPN
admet-189	620	7	,	,	PUNCT
admet-189	620	8	g.	g.	PROPN
admet-189	620	9	senthil	senthil	PROPN
admet-189	620	10	,	,	PUNCT
admet-189	620	11	r.	r.	PROPN
admet-189	620	12	saunders	saunders	PROPN
admet-189	620	13	-	-	PUNCT
admet-189	620	14	pullman	pullman	PROPN
admet-189	620	15	,	,	PUNCT
admet-189	620	16	e.	e.	PROPN
admet-189	620	17	ohmann	ohmann	PROPN
admet-189	620	18	,	,	PUNCT
admet-189	620	19	a.	a.	NOUN
admet-189	620	20	deligtisch	deligtisch	PROPN
admet-189	620	21	,	,	PUNCT
admet-189	620	22	m.	m.	NOUN
admet-189	620	23	tagliati	tagliati	PROPN
admet-189	620	24	,	,	PUNCT
admet-189	620	25	a.l	a.l	PROPN
admet-189	620	26	.	.	PROPN
admet-189	620	27	hunt	hunt	PROPN
admet-189	620	28	,	,	PUNCT
admet-189	620	29	c.	c.	PROPN
admet-189	620	30	klein	klein	PROPN
admet-189	620	31	,	,	PUNCT
admet-189	620	32	b.	b.	PROPN
admet-189	620	33	henick	henick	PROPN
admet-189	620	34	,	,	PUNCT
admet-189	620	35	s.m	s.m	PROPN
admet-189	620	36	.	.	PROPN
admet-189	620	37	hailpern	hailpern	PROPN
admet-189	620	38	,	,	PUNCT
admet-189	620	39	r.b	r.b	PROPN
admet-189	620	40	.	.	PROPN
admet-189	620	41	lipton	lipton	PROPN
admet-189	620	42	,	,	PUNCT
admet-189	620	43	j.	j.	PROPN
admet-189	620	44	soto	soto	PROPN
admet-189	620	45	-	-	PUNCT
admet-189	620	46	valencia	valencia	PROPN
admet-189	620	47	,	,	PUNCT
admet-189	620	48	n.	n.	PROPN
admet-189	620	49	risch	risch	PROPN
admet-189	620	50	,	,	PUNCT
admet-189	620	51	s.b	s.b	PROPN
admet-189	620	52	.	.	PROPN
admet-189	620	53	bressman	bressman	PROPN
admet-189	620	54	,	,	PUNCT
admet-189	620	55	n.	n.	PROPN
admet-189	620	56	engl	engl	PROPN
admet-189	620	57	.	.	PUNCT
admet-189	621	1	j.	j.	PROPN
admet-189	621	2	med	med	PROPN
admet-189	621	3	.	.	PUNCT
admet-189	622	1	354	354	NUM
admet-189	622	2	(	(	PUNCT
admet-189	622	3	2006	2006	NUM
admet-189	622	4	)	)	PUNCT
admet-189	622	5	424	424	NUM
admet-189	622	6	-	-	SYM
admet-189	622	7	425	425	NUM
admet-189	622	8	.	.	PUNCT
admet-189	623	1	[	[	X
admet-189	623	2	25	25	NUM
admet-189	623	3	]	]	X
admet-189	623	4	h.	h.	PROPN
admet-189	623	5	asada	asada	PROPN
admet-189	623	6	,	,	PUNCT
admet-189	623	7	n.	n.	PROPN
admet-189	623	8	ip	ip	PROPN
admet-189	623	9	,	,	PUNCT
admet-189	623	10	l.	l.	PROPN
admet-189	623	11	pan	pan	PROPN
admet-189	623	12	,	,	PUNCT
admet-189	623	13	n.	n.	NOUN
admet-189	623	14	razack	razack	NOUN
admet-189	623	15	,	,	PUNCT
admet-189	623	16	m.	m.	NOUN
admet-189	623	17	parfitt	parfitt	NOUN
admet-189	623	18	,	,	PUNCT
admet-189	623	19	r.j	r.j	PROPN
admet-189	623	20	.	.	PROPN
admet-189	623	21	plunkett	plunkett	PROPN
admet-189	623	22	,	,	PUNCT
admet-189	623	23	j.	j.	PROPN
admet-189	623	24	neurosci	neurosci	PROPN
admet-189	623	25	.	.	PUNCT
admet-189	624	1	res	re	NOUN
admet-189	624	2	.	.	PROPN
admet-189	625	1	40	40	NUM
admet-189	625	2	(	(	PUNCT
admet-189	625	3	1995	1995	NUM
admet-189	625	4	)	)	PUNCT
admet-189	625	5	22	22	NUM
admet-189	625	6	-	-	SYM
admet-189	625	7	30	30	NUM
admet-189	625	8	.	.	PUNCT
admet-189	626	1	[	[	X
admet-189	626	2	26	26	NUM
admet-189	626	3	]	]	SYM
admet-189	626	4	p.m.	p.m.	NOUN
admet-189	626	5	antony	antony	PROPN
admet-189	626	6	,	,	PUNCT
admet-189	626	7	n.j	n.j	PROPN
admet-189	626	8	.	.	PROPN
admet-189	626	9	diederich	diederich	PROPN
admet-189	626	10	,	,	PUNCT
admet-189	626	11	r.	r.	PROPN
admet-189	626	12	kruger	kruger	PROPN
admet-189	626	13	,	,	PUNCT
admet-189	626	14	r.	r.	PROPN
admet-189	626	15	balling	balling	PROPN
admet-189	626	16	,	,	PUNCT
admet-189	626	17	febs	febs	NOUN
admet-189	626	18	j.	j.	PROPN
admet-189	626	19	280	280	NUM
admet-189	626	20	(	(	PUNCT
admet-189	626	21	2013	2013	NUM
admet-189	626	22	)	)	PUNCT
admet-189	626	23	5981	5981	NUM
admet-189	626	24	-	-	SYM
admet-189	626	25	5993	5993	NUM
admet-189	626	26	.	.	PUNCT
admet-189	627	1	[	[	X
admet-189	627	2	27	27	NUM
admet-189	627	3	]	]	X
admet-189	627	4	y.	y.	PROPN
admet-189	627	5	chu	chu	PROPN
admet-189	627	6	,	,	PUNCT
admet-189	627	7	h.	h.	PROPN
admet-189	627	8	dodiya	dodiya	PROPN
admet-189	627	9	,	,	PUNCT
admet-189	627	10	p.	p.	PROPN
admet-189	627	11	aebischer	aebischer	ADJ
admet-189	627	12	,	,	PUNCT
admet-189	627	13	c.w	c.w	PROPN
admet-189	627	14	.	.	PROPN
admet-189	627	15	olanow	olanow	PROPN
admet-189	627	16	,	,	PUNCT
admet-189	627	17	j.h	j.h	PROPN
admet-189	627	18	.	.	PROPN
admet-189	627	19	kordower	kordower	PROPN
admet-189	627	20	,	,	PUNCT
admet-189	627	21	neurobiol	neurobiol	PROPN
admet-189	627	22	.	.	PUNCT
admet-189	628	1	dis	dis	PROPN
admet-189	628	2	.	.	PROPN
admet-189	629	1	35	35	NUM
admet-189	629	2	(	(	PUNCT
admet-189	629	3	2009	2009	NUM
admet-189	629	4	)	)	PUNCT
admet-189	629	5	385	385	NUM
admet-189	629	6	-	-	SYM
admet-189	629	7	398	398	NUM
admet-189	629	8	.	.	PUNCT
admet-189	630	1	[	[	X
admet-189	630	2	28	28	NUM
admet-189	630	3	]	]	X
admet-189	630	4	s.l	s.l	PROPN
admet-189	630	5	.	.	PROPN
admet-189	630	6	rhodes	rhodes	PROPN
admet-189	630	7	,	,	PUNCT
admet-189	630	8	b.	b.	PROPN
admet-189	630	9	ritz	ritz	PROPN
admet-189	630	10	,	,	PUNCT
admet-189	630	11	neurobiol	neurobiol	PROPN
admet-189	630	12	.	.	PUNCT
admet-189	631	1	dis	dis	PROPN
admet-189	631	2	.	.	PUNCT
admet-189	632	1	32	32	NUM
admet-189	632	2	(	(	PUNCT
admet-189	632	3	2008	2008	NUM
admet-189	632	4	)	)	PUNCT
admet-189	632	5	183	183	NUM
admet-189	632	6	-	-	SYM
admet-189	632	7	195	195	NUM
admet-189	632	8	.	.	PUNCT
admet-189	633	1	[	[	X
admet-189	633	2	29	29	NUM
admet-189	633	3	]	]	PUNCT
admet-189	633	4	z.	z.	PROPN
admet-189	633	5	lv	lv	PROPN
admet-189	633	6	,	,	PUNCT
admet-189	633	7	h.	h.	PROPN
admet-189	633	8	jiang	jiang	PROPN
admet-189	633	9	,	,	PUNCT
admet-189	633	10	h.	h.	PROPN
admet-189	633	11	xu	xu	PROPN
admet-189	633	12	,	,	PUNCT
admet-189	633	13	n.	n.	NOUN
admet-189	633	14	song	song	PROPN
admet-189	633	15	,	,	PUNCT
admet-189	633	16	j.	j.	PROPN
admet-189	633	17	xie	xie	PROPN
admet-189	633	18	,	,	PUNCT
admet-189	633	19	j.	j.	PROPN
admet-189	633	20	neural	neural	PROPN
admet-189	633	21	.	.	PUNCT
admet-189	634	1	transm	transm	PROPN
admet-189	634	2	.	.	PUNCT
admet-189	635	1	118	118	NUM
admet-189	635	2	(	(	PUNCT
admet-189	635	3	2011	2011	NUM
admet-189	635	4	)	)	PUNCT
admet-189	635	5	361	361	NUM
admet-189	635	6	-	-	SYM
admet-189	635	7	369	369	NUM
admet-189	635	8	.	.	PUNCT
admet-189	636	1	[	[	X
admet-189	636	2	30	30	NUM
admet-189	636	3	]	]	X
admet-189	636	4	s.a	s.a	PROPN
admet-189	636	5	.	.	PROPN
admet-189	636	6	schneider	schneider	PROPN
admet-189	636	7	,	,	PUNCT
admet-189	636	8	c.	c.	PROPN
admet-189	636	9	paisan	paisan	NOUN
admet-189	636	10	-	-	PUNCT
admet-189	636	11	ruiz	ruiz	NOUN
admet-189	636	12	,	,	PUNCT
admet-189	636	13	n.p	n.p	PROPN
admet-189	636	14	.	.	PROPN
admet-189	636	15	quinn	quinn	PROPN
admet-189	636	16	,	,	PUNCT
admet-189	636	17	a.j	a.j	PROPN
admet-189	636	18	.	.	PROPN
admet-189	636	19	lees	lee	NOUN
admet-189	636	20	,	,	PUNCT
admet-189	636	21	h.	h.	PROPN
admet-189	636	22	houlden	houlden	PROPN
admet-189	636	23	,	,	PUNCT
admet-189	636	24	j.	j.	PROPN
admet-189	636	25	hardy	hardy	PROPN
admet-189	636	26	,	,	PUNCT
admet-189	636	27	k.p	k.p	PROPN
admet-189	636	28	.	.	PROPN
admet-189	636	29	bhatia	bhatia	PROPN
admet-189	636	30	,	,	PUNCT
admet-189	636	31	mov	mov	PROPN
admet-189	636	32	.	.	PUNCT
admet-189	637	1	disord	disord	PROPN
admet-189	637	2	.	.	PUNCT
admet-189	638	1	25	25	NUM
admet-189	638	2	(	(	PUNCT
admet-189	638	3	2010	2010	NUM
admet-189	638	4	)	)	PUNCT
admet-189	638	5	979	979	NUM
admet-189	638	6	-	-	SYM
admet-189	638	7	984	984	NUM
admet-189	638	8	.	.	PUNCT
admet-189	639	1	[	[	X
admet-189	639	2	31	31	NUM
admet-189	639	3	]	]	PUNCT
admet-189	639	4	a.	a.	NOUN
admet-189	639	5	mcneill	mcneill	PROPN
admet-189	639	6	,	,	PUNCT
admet-189	639	7	curr	curr	PROPN
admet-189	639	8	.	.	PUNCT
admet-189	639	9	drug	drug	NOUN
admet-189	639	10	targets	target	NOUN
admet-189	639	11	13	13	NUM
admet-189	639	12	(	(	PUNCT
admet-189	639	13	2012	2012	NUM
admet-189	639	14	)	)	PUNCT
admet-189	639	15	1204	1204	NUM
admet-189	639	16	-	-	SYM
admet-189	639	17	1206	1206	NUM
admet-189	639	18	.	.	PUNCT
admet-189	640	1	[	[	X
admet-189	640	2	32	32	NUM
admet-189	640	3	]	]	PUNCT
admet-189	640	4	e.	e.	PROPN
admet-189	640	5	tolosa	tolosa	PROPN
admet-189	640	6	,	,	PUNCT
admet-189	640	7	g.	g.	PROPN
admet-189	640	8	wenning	wenning	PROPN
admet-189	640	9	,	,	PUNCT
admet-189	640	10	w.	w.	PROPN
admet-189	640	11	poewe	poewe	PROPN
admet-189	640	12	,	,	PUNCT
admet-189	640	13	lancet	lancet	NOUN
admet-189	640	14	neurol	neurol	NOUN
admet-189	640	15	.	.	PUNCT
admet-189	641	1	5	5	NUM
admet-189	641	2	(	(	PUNCT
admet-189	641	3	2006	2006	NUM
admet-189	641	4	)	)	PUNCT
admet-189	641	5	75	75	NUM
admet-189	641	6	-	-	SYM
admet-189	641	7	86	86	NUM
admet-189	641	8	.	.	PUNCT
admet-189	642	1	[	[	X
admet-189	642	2	33	33	NUM
admet-189	642	3	]	]	X
admet-189	642	4	j.	j.	PROPN
admet-189	642	5	booij	booij	PROPN
admet-189	642	6	,	,	PUNCT
admet-189	642	7	j.d	j.d	PROPN
admet-189	642	8	.	.	PROPN
admet-189	642	9	speelman	speelman	PROPN
admet-189	642	10	,	,	PUNCT
admet-189	642	11	m.w	m.w	PROPN
admet-189	642	12	.	.	PROPN
admet-189	642	13	horstink	horstink	PROPN
admet-189	642	14	,	,	PUNCT
admet-189	642	15	e.c	e.c	PROPN
admet-189	642	16	.	.	PROPN
admet-189	642	17	wolters	wolters	PROPN
admet-189	642	18	,	,	PUNCT
admet-189	642	19	eur	eur	PROPN
admet-189	642	20	.	.	PUNCT
admet-189	642	21	j.	j.	PROPN
admet-189	642	22	nucl	nucl	PROPN
admet-189	642	23	.	.	PUNCT
admet-189	642	24	med	med	PROPN
admet-189	642	25	.	.	PUNCT
admet-189	643	1	28	28	NUM
admet-189	643	2	(	(	PUNCT
admet-189	643	3	2001	2001	NUM
admet-189	643	4	)	)	PUNCT
admet-189	643	5	266	266	NUM
admet-189	643	6	-	-	SYM
admet-189	643	7	272	272	NUM
admet-189	643	8	.	.	PUNCT
admet-189	644	1	[	[	X
admet-189	644	2	34	34	NUM
admet-189	644	3	]	]	X
admet-189	644	4	b.s	b.s	PROPN
admet-189	644	5	.	.	PROPN
admet-189	644	6	connolly	connolly	PROPN
admet-189	644	7	,	,	PUNCT
admet-189	644	8	a.e	a.e	PROPN
admet-189	644	9	.	.	PROPN
admet-189	644	10	lang	lang	PROPN
admet-189	644	11	,	,	PUNCT
admet-189	644	12	jama	jama	PROPN
admet-189	644	13	311	311	NUM
admet-189	644	14	(	(	PUNCT
admet-189	644	15	2014	2014	NUM
admet-189	644	16	)	)	PUNCT
admet-189	644	17	1670	1670	NUM
admet-189	644	18	-	-	SYM
admet-189	644	19	1683	1683	NUM
admet-189	644	20	.	.	PUNCT
admet-189	645	1	[	[	X
admet-189	645	2	35	35	NUM
admet-189	645	3	]	]	PUNCT
admet-189	645	4	t.	t.	NOUN
admet-189	645	5	nagatsua	nagatsua	PROPN
admet-189	645	6	,	,	PUNCT
admet-189	645	7	m.	m.	NOUN
admet-189	645	8	sawadab	sawadab	PROPN
admet-189	645	9	,	,	PUNCT
admet-189	645	10	parkinsonism	parkinsonism	PROPN
admet-189	645	11	relat	relat	PROPN
admet-189	645	12	.	.	PUNCT
admet-189	646	1	disord	disord	NOUN
admet-189	646	2	.	.	PUNCT
admet-189	647	1	15	15	NUM
admet-189	647	2	suppl	suppl	ADJ
admet-189	647	3	1	1	NUM
admet-189	647	4	(	(	PUNCT
admet-189	647	5	2009	2009	NUM
admet-189	647	6	)	)	PUNCT
admet-189	647	7	s3	s3	PROPN
admet-189	647	8	-	-	PUNCT
admet-189	647	9	8	8	NUM
admet-189	647	10	.	.	PUNCT
admet-189	648	1	[	[	X
admet-189	648	2	36	36	NUM
admet-189	648	3	]	]	X
admet-189	648	4	h.m	h.m	PROPN
admet-189	648	5	.	.	PROPN
admet-189	648	6	ruottinen	ruottinen	PROPN
admet-189	648	7	,	,	PUNCT
admet-189	648	8	u.k	u.k	PROPN
admet-189	648	9	.	.	PROPN
admet-189	648	10	rinne	rinne	PROPN
admet-189	648	11	,	,	PUNCT
admet-189	648	12	j.	j.	PROPN
admet-189	648	13	neurol	neurol	PROPN
admet-189	648	14	.	.	PUNCT
admet-189	649	1	245	245	NUM
admet-189	649	2	(	(	PUNCT
admet-189	649	3	1998	1998	NUM
admet-189	649	4	)	)	PUNCT
admet-189	649	5	p25	p25	PROPN
admet-189	649	6	-	-	PUNCT
admet-189	649	7	34	34	NUM
admet-189	649	8	.	.	PUNCT
admet-189	650	1	[	[	X
admet-189	650	2	37	37	NUM
admet-189	650	3	]	]	X
admet-189	650	4	a.h	a.h	PROPN
admet-189	650	5	.	.	PROPN
admet-189	650	6	schapira	schapira	PROPN
admet-189	650	7	,	,	PUNCT
admet-189	650	8	f.	f.	PROPN
admet-189	650	9	stocchi	stocchi	PROPN
admet-189	650	10	,	,	PUNCT
admet-189	650	11	r.	r.	NOUN
admet-189	650	12	borgohain	borgohain	NOUN
admet-189	650	13	,	,	PUNCT
admet-189	650	14	m.	m.	NOUN
admet-189	650	15	onofrj	onofrj	NOUN
admet-189	650	16	,	,	PUNCT
admet-189	650	17	m.	m.	NOUN
admet-189	650	18	bhatt	bhatt	PROPN
admet-189	650	19	,	,	PUNCT
admet-189	650	20	p.	p.	PROPN
admet-189	650	21	lorenzana	lorenzana	PROPN
admet-189	650	22	,	,	PUNCT
admet-189	650	23	v.	v.	ADP
admet-189	650	24	lucini	lucini	PROPN
admet-189	650	25	,	,	PUNCT
admet-189	650	26	r.	r.	PROPN
admet-189	650	27	giuliani	giuliani	PROPN
admet-189	650	28	,	,	PUNCT
admet-189	650	29	r.	r.	PROPN
admet-189	650	30	anand	anand	PROPN
admet-189	650	31	,	,	PUNCT
admet-189	650	32	eur	eur	PROPN
admet-189	650	33	.	.	PUNCT
admet-189	650	34	j.	j.	PROPN
admet-189	650	35	neurol	neurol	PROPN
admet-189	650	36	.	.	PUNCT
admet-189	651	1	20	20	NUM
admet-189	651	2	(	(	PUNCT
admet-189	651	3	2013	2013	NUM
admet-189	651	4	)	)	PUNCT
admet-189	651	5	271	271	NUM
admet-189	651	6	-	-	SYM
admet-189	651	7	280	280	NUM
admet-189	651	8	.	.	PUNCT
admet-189	652	1	[	[	X
admet-189	652	2	38	38	NUM
admet-189	652	3	]	]	PUNCT
admet-189	652	4	f.	f.	PROPN
admet-189	652	5	stocchi	stocchi	PROPN
admet-189	652	6	,	,	PUNCT
admet-189	652	7	r.	r.	NOUN
admet-189	652	8	borgohain	borgohain	NOUN
admet-189	652	9	,	,	PUNCT
admet-189	652	10	m.	m.	NOUN
admet-189	652	11	onofrj	onofrj	NOUN
admet-189	652	12	,	,	PUNCT
admet-189	652	13	a.h	a.h	PROPN
admet-189	652	14	.	.	PROPN
admet-189	652	15	schapira	schapira	PROPN
admet-189	652	16	,	,	PUNCT
admet-189	652	17	m.	m.	NOUN
admet-189	652	18	bhatt	bhatt	PROPN
admet-189	652	19	,	,	PUNCT
admet-189	652	20	v.	v.	ADP
admet-189	652	21	lucini	lucini	PROPN
admet-189	652	22	,	,	PUNCT
admet-189	652	23	r.	r.	PROPN
admet-189	652	24	giuliani	giuliani	PROPN
admet-189	652	25	,	,	PUNCT
admet-189	652	26	r.	r.	PROPN
admet-189	652	27	anand	anand	PROPN
admet-189	652	28	,	,	PUNCT
admet-189	652	29	mov	mov	PROPN
admet-189	652	30	.	.	PUNCT
admet-189	652	31	disord	disord	PROPN
admet-189	652	32	.	.	PUNCT
admet-189	653	1	27	27	NUM
admet-189	653	2	(	(	PUNCT
admet-189	653	3	2012	2012	NUM
admet-189	653	4	)	)	PUNCT
admet-189	653	5	106	106	NUM
admet-189	653	6	-	-	SYM
admet-189	653	7	112	112	NUM
admet-189	653	8	.	.	PUNCT
admet-189	654	1	[	[	X
admet-189	654	2	39	39	NUM
admet-189	654	3	]	]	PUNCT
admet-189	654	4	w.	w.	PROPN
admet-189	654	5	bara	bara	PROPN
admet-189	654	6	-	-	PUNCT
admet-189	654	7	jimenez	jimenez	PROPN
admet-189	654	8	,	,	PUNCT
admet-189	654	9	a.	a.	NOUN
admet-189	654	10	sherzai	sherzai	NOUN
admet-189	654	11	,	,	PUNCT
admet-189	654	12	t.	t.	PROPN
admet-189	654	13	dimitrova	dimitrova	PROPN
admet-189	654	14	,	,	PUNCT
admet-189	654	15	a.	a.	NOUN
admet-189	654	16	favit	favit	PROPN
admet-189	654	17	,	,	PUNCT
admet-189	654	18	f.	f.	PROPN
admet-189	654	19	bibbiani	bibbiani	PROPN
admet-189	654	20	,	,	PUNCT
admet-189	654	21	m.	m.	NOUN
admet-189	654	22	gillespie	gillespie	PROPN
admet-189	654	23	,	,	PUNCT
admet-189	654	24	m.	m.	NOUN
admet-189	654	25	morris	morris	PROPN
admet-189	654	26	,	,	PUNCT
admet-189	654	27	m.	m.	NOUN
admet-189	654	28	mouradian	mouradian	NOUN
admet-189	654	29	,	,	PUNCT
admet-189	654	30	t.	t.	NOUN
admet-189	654	31	chase	chase	NOUN
admet-189	654	32	,	,	PUNCT
admet-189	654	33	neurology	neurology	NOUN
admet-189	654	34	61	61	NUM
admet-189	654	35	(	(	PUNCT
admet-189	654	36	2003	2003	NUM
admet-189	654	37	)	)	PUNCT
admet-189	654	38	293	293	NUM
admet-189	654	39	-	-	SYM
admet-189	654	40	296	296	NUM
admet-189	654	41	.	.	PUNCT
admet-189	654	42	r.	r.	PROPN
admet-189	654	43	banerjee	banerjee	PROPN
admet-189	654	44	et	et	PROPN
admet-189	654	45	al	al	PROPN
admet-189	654	46	.	.	PROPN
admet-189	654	47	admet	admet	PROPN
admet-189	654	48	&	&	CCONJ
admet-189	654	49	dmpk	dmpk	PROPN
admet-189	654	50	3(3	3(3	NUM
admet-189	654	51	)	)	PUNCT
admet-189	654	52	(	(	PUNCT
admet-189	654	53	2015	2015	NUM
admet-189	654	54	)	)	PUNCT
admet-189	654	55	155	155	NUM
admet-189	654	56	-	-	SYM
admet-189	654	57	181	181	NUM
admet-189	654	58	178	178	NUM
admet-189	654	59	[	[	X
admet-189	654	60	40	40	NUM
admet-189	654	61	]	]	PUNCT
admet-189	654	62	f.	f.	PROPN
admet-189	654	63	stocchi	stocchi	PROPN
admet-189	654	64	,	,	PUNCT
admet-189	654	65	o.	o.	PROPN
admet-189	654	66	rascol	rascol	PROPN
admet-189	654	67	,	,	PUNCT
admet-189	654	68	a.	a.	NOUN
admet-189	654	69	destee	destee	NOUN
admet-189	654	70	,	,	PUNCT
admet-189	654	71	n.	n.	PROPN
admet-189	654	72	hattori	hattori	PROPN
admet-189	654	73	,	,	PUNCT
admet-189	654	74	r.a	r.a	PROPN
admet-189	654	75	.	.	PROPN
admet-189	654	76	hauser	hauser	PROPN
admet-189	654	77	,	,	PUNCT
admet-189	654	78	a.e	a.e	PROPN
admet-189	654	79	.	.	PROPN
admet-189	654	80	lang	lang	PROPN
admet-189	654	81	,	,	PUNCT
admet-189	654	82	w.	w.	PROPN
admet-189	654	83	poewe	poewe	PROPN
admet-189	654	84	,	,	PUNCT
admet-189	654	85	m.	m.	NOUN
admet-189	654	86	stacy	stacy	PROPN
admet-189	654	87	,	,	PUNCT
admet-189	654	88	e.	e.	PROPN
admet-189	654	89	tolosa	tolosa	PROPN
admet-189	654	90	,	,	PUNCT
admet-189	654	91	h.	h.	PROPN
admet-189	654	92	gao	gao	PROPN
admet-189	654	93	,	,	PUNCT
admet-189	654	94	j.	j.	PROPN
admet-189	654	95	nagel	nagel	PROPN
admet-189	654	96	,	,	PUNCT
admet-189	654	97	m.	m.	NOUN
admet-189	654	98	merschhemke	merschhemke	PROPN
admet-189	654	99	,	,	PUNCT
admet-189	654	100	a.	a.	NOUN
admet-189	654	101	graf	graf	PROPN
admet-189	654	102	,	,	PUNCT
admet-189	654	103	c.	c.	PROPN
admet-189	654	104	kenney	kenney	PROPN
admet-189	654	105	,	,	PUNCT
admet-189	654	106	c.	c.	PROPN
admet-189	654	107	trenkwalder	trenkwalder	PROPN
admet-189	654	108	,	,	PUNCT
admet-189	654	109	mov	mov	NOUN
admet-189	654	110	.	.	PUNCT
admet-189	654	111	disord	disord	PROPN
admet-189	654	112	.	.	PUNCT
admet-189	655	1	28	28	NUM
admet-189	655	2	(	(	PUNCT
admet-189	655	3	2013	2013	NUM
admet-189	655	4	)	)	PUNCT
admet-189	655	5	18381846	18381846	NUM
admet-189	655	6	.	.	PUNCT
admet-189	656	1	[	[	X
admet-189	656	2	41	41	NUM
admet-189	656	3	]	]	X
admet-189	656	4	p.	p.	PROPN
admet-189	656	5	jenner	jenner	PROPN
admet-189	656	6	,	,	PUNCT
admet-189	656	7	ann	ann	PROPN
admet-189	656	8	.	.	PUNCT
admet-189	657	1	neurol	neurol	PROPN
admet-189	657	2	.	.	PUNCT
admet-189	658	1	53	53	NUM
admet-189	658	2	suppl	suppl	ADJ
admet-189	658	3	3	3	NUM
admet-189	658	4	(	(	PUNCT
admet-189	658	5	2003	2003	NUM
admet-189	658	6	)	)	PUNCT
admet-189	658	7	s26	s26	NOUN
admet-189	658	8	-	-	PUNCT
admet-189	658	9	36	36	NUM
admet-189	658	10	;	;	PUNCT
admet-189	658	11	discussion	discussion	NOUN
admet-189	658	12	s36	s36	PROPN
admet-189	658	13	-	-	PUNCT
admet-189	658	14	38	38	NUM
admet-189	658	15	.	.	PUNCT
admet-189	659	1	[	[	X
admet-189	659	2	42	42	NUM
admet-189	659	3	]	]	X
admet-189	659	4	l.f	l.f	PROPN
admet-189	659	5	.	.	PROPN
admet-189	659	6	lin	lin	PROPN
admet-189	659	7	,	,	PUNCT
admet-189	659	8	d.h	d.h	PROPN
admet-189	659	9	.	.	PROPN
admet-189	659	10	doherty	doherty	PROPN
admet-189	659	11	,	,	PUNCT
admet-189	659	12	j.d	j.d	PROPN
admet-189	659	13	.	.	PROPN
admet-189	659	14	lile	lile	PROPN
admet-189	659	15	,	,	PUNCT
admet-189	659	16	s.	s.	PROPN
admet-189	659	17	bektesh	bektesh	PROPN
admet-189	659	18	,	,	PUNCT
admet-189	659	19	f.	f.	PROPN
admet-189	659	20	collins	collins	PROPN
admet-189	659	21	,	,	PUNCT
admet-189	659	22	science	science	NOUN
admet-189	659	23	260	260	NUM
admet-189	659	24	(	(	PUNCT
admet-189	659	25	1993	1993	NUM
admet-189	659	26	)	)	PUNCT
admet-189	659	27	1130	1130	NUM
admet-189	659	28	-	-	SYM
admet-189	659	29	1132	1132	NUM
admet-189	659	30	.	.	PUNCT
admet-189	660	1	[	[	X
admet-189	660	2	43	43	NUM
admet-189	660	3	]	]	X
admet-189	660	4	a.e	a.e	PROPN
admet-189	660	5	.	.	PROPN
admet-189	660	6	lang	lang	PROPN
admet-189	660	7	,	,	PUNCT
admet-189	660	8	j.w	j.w	PROPN
admet-189	660	9	.	.	PROPN
admet-189	660	10	langston	langston	PROPN
admet-189	660	11	,	,	PUNCT
admet-189	660	12	a.j	a.j	PROPN
admet-189	660	13	.	.	PROPN
admet-189	660	14	stoessl	stoessl	PROPN
admet-189	660	15	,	,	PUNCT
admet-189	660	16	m.	m.	NOUN
admet-189	660	17	brodsky	brodsky	PROPN
admet-189	660	18	,	,	PUNCT
admet-189	660	19	d.j	d.j	PROPN
admet-189	660	20	.	.	PROPN
admet-189	660	21	brooks	brooks	PROPN
admet-189	660	22	,	,	PUNCT
admet-189	660	23	v.	v.	X
admet-189	660	24	dhawan	dhawan	PROPN
admet-189	660	25	,	,	PUNCT
admet-189	660	26	w.j	w.j	PROPN
admet-189	660	27	.	.	PROPN
admet-189	660	28	elias	elias	PROPN
admet-189	660	29	,	,	PUNCT
admet-189	660	30	a.m.	a.m.	PROPN
admet-189	660	31	lozano	lozano	PROPN
admet-189	660	32	,	,	PUNCT
admet-189	660	33	e.	e.	PROPN
admet-189	660	34	moro	moro	PROPN
admet-189	660	35	,	,	PUNCT
admet-189	660	36	j.g	j.g	PROPN
admet-189	660	37	.	.	PROPN
admet-189	660	38	nutt	nutt	PROPN
admet-189	660	39	,	,	PUNCT
admet-189	660	40	m.	m.	NOUN
admet-189	660	41	stacy	stacy	PROPN
admet-189	660	42	,	,	PUNCT
admet-189	660	43	d.	d.	PROPN
admet-189	660	44	turner	turner	PROPN
admet-189	660	45	,	,	PUNCT
admet-189	660	46	g.f	g.f	PROPN
admet-189	660	47	.	.	PROPN
admet-189	660	48	wooten	wooten	PROPN
admet-189	660	49	,	,	PUNCT
admet-189	660	50	lancet	lancet	PROPN
admet-189	660	51	neurol	neurol	NOUN
admet-189	660	52	.	.	PUNCT
admet-189	661	1	5	5	NUM
admet-189	661	2	(	(	PUNCT
admet-189	661	3	2006	2006	NUM
admet-189	661	4	)	)	PUNCT
admet-189	661	5	200	200	NUM
admet-189	661	6	-	-	SYM
admet-189	661	7	202	202	NUM
admet-189	661	8	.	.	PUNCT
admet-189	662	1	[	[	X
admet-189	662	2	44	44	NUM
admet-189	662	3	]	]	SYM
admet-189	662	4	n.d	n.d	PROPN
admet-189	662	5	.	.	PROPN
admet-189	662	6	doolittle	doolittle	PROPN
admet-189	662	7	,	,	PUNCT
admet-189	662	8	l.e	l.e	PROPN
admet-189	662	9	.	.	PROPN
admet-189	662	10	abrey	abrey	PROPN
admet-189	662	11	,	,	PUNCT
admet-189	662	12	w.a	w.a	PROPN
admet-189	662	13	.	.	PROPN
admet-189	662	14	bleyer	bleyer	PROPN
admet-189	662	15	,	,	PUNCT
admet-189	662	16	s.	s.	PROPN
admet-189	662	17	brem	brem	PROPN
admet-189	662	18	,	,	PUNCT
admet-189	662	19	t.p	t.p	PROPN
admet-189	662	20	.	.	PROPN
admet-189	662	21	davis	davis	PROPN
admet-189	662	22	,	,	PUNCT
admet-189	662	23	p.	p.	PROPN
admet-189	662	24	dore	dore	PROPN
admet-189	662	25	-	-	PUNCT
admet-189	662	26	duffy	duffy	PROPN
admet-189	662	27	,	,	PUNCT
admet-189	662	28	l.r	l.r	PROPN
admet-189	662	29	.	.	PROPN
admet-189	662	30	drewes	drewes	PROPN
admet-189	662	31	,	,	PUNCT
admet-189	662	32	w.a	w.a	PROPN
admet-189	662	33	.	.	PROPN
admet-189	662	34	hall	hall	PROPN
admet-189	662	35	,	,	PUNCT
admet-189	662	36	j.m	j.m	PROPN
admet-189	662	37	.	.	PROPN
admet-189	662	38	hoffman	hoffman	PROPN
admet-189	662	39	,	,	PUNCT
admet-189	662	40	a.	a.	NOUN
admet-189	662	41	korfel	korfel	PROPN
admet-189	662	42	,	,	PUNCT
admet-189	662	43	r.	r.	PROPN
admet-189	662	44	martuza	martuza	PROPN
admet-189	662	45	,	,	PUNCT
admet-189	662	46	l.l	l.l	PROPN
admet-189	662	47	.	.	PROPN
admet-189	662	48	muldoon	muldoon	PROPN
admet-189	662	49	,	,	PUNCT
admet-189	662	50	d.	d.	PROPN
admet-189	662	51	peereboom	peereboom	PROPN
admet-189	662	52	,	,	PUNCT
admet-189	662	53	d.r	d.r	PROPN
admet-189	662	54	.	.	PROPN
admet-189	662	55	peterson	peterson	PROPN
admet-189	662	56	,	,	PUNCT
admet-189	662	57	s.d	s.d	PROPN
admet-189	662	58	.	.	PROPN
admet-189	662	59	rabkin	rabkin	PROPN
admet-189	662	60	,	,	PUNCT
admet-189	662	61	q.	q.	PROPN
admet-189	662	62	smith	smith	PROPN
admet-189	662	63	,	,	PUNCT
admet-189	662	64	g.h	g.h	PROPN
admet-189	662	65	.	.	PROPN
admet-189	662	66	stevens	stevens	PROPN
admet-189	662	67	,	,	PUNCT
admet-189	662	68	e.a	e.a	PROPN
admet-189	662	69	.	.	PROPN
admet-189	662	70	neuwelt	neuwelt	PROPN
admet-189	662	71	,	,	PUNCT
admet-189	662	72	clin	clin	PROPN
admet-189	662	73	.	.	PUNCT
admet-189	663	1	cancer	cancer	NOUN
admet-189	663	2	res	re	NOUN
admet-189	663	3	.	.	PUNCT
admet-189	664	1	11	11	NUM
admet-189	664	2	(	(	PUNCT
admet-189	664	3	2005	2005	NUM
admet-189	664	4	)	)	PUNCT
admet-189	664	5	421	421	NUM
admet-189	664	6	-	-	SYM
admet-189	664	7	428	428	NUM
admet-189	664	8	.	.	PUNCT
admet-189	665	1	[	[	X
admet-189	665	2	45	45	NUM
admet-189	665	3	]	]	X
admet-189	665	4	y.	y.	PROPN
admet-189	665	5	persidsky	persidsky	PROPN
admet-189	665	6	,	,	PUNCT
admet-189	665	7	s.h	s.h	PROPN
admet-189	665	8	.	.	PROPN
admet-189	665	9	ramirez	ramirez	PROPN
admet-189	665	10	,	,	PUNCT
admet-189	665	11	j.	j.	PROPN
admet-189	665	12	haorah	haorah	PROPN
admet-189	665	13	,	,	PUNCT
admet-189	665	14	g.d	g.d	PROPN
admet-189	665	15	.	.	PROPN
admet-189	665	16	kanmogne	kanmogne	PROPN
admet-189	665	17	,	,	PUNCT
admet-189	665	18	j.	j.	PROPN
admet-189	665	19	neuroimmune	neuroimmune	PROPN
admet-189	665	20	pharmacol	pharmacol	PROPN
admet-189	665	21	.	.	PROPN
admet-189	665	22	1	1	NUM
admet-189	665	23	(	(	PUNCT
admet-189	665	24	2006	2006	NUM
admet-189	665	25	)	)	PUNCT
admet-189	665	26	223236	223236	NUM
admet-189	665	27	.	.	PUNCT
admet-189	666	1	[	[	X
admet-189	666	2	46	46	NUM
admet-189	666	3	]	]	X
admet-189	666	4	w.h	w.h	PROPN
admet-189	666	5	.	.	PROPN
admet-189	666	6	oldendorf	oldendorf	PROPN
admet-189	666	7	,	,	PUNCT
admet-189	666	8	m.e	m.e	PROPN
admet-189	666	9	.	.	PROPN
admet-189	666	10	cornford	cornford	PROPN
admet-189	666	11	,	,	PUNCT
admet-189	666	12	w.j	w.j	PROPN
admet-189	666	13	.	.	PROPN
admet-189	666	14	brown	brown	PROPN
admet-189	666	15	,	,	PUNCT
admet-189	666	16	ann	ann	PROPN
admet-189	666	17	.	.	PUNCT
admet-189	667	1	neurol	neurol	PROPN
admet-189	667	2	.	.	PUNCT
admet-189	668	1	1	1	NUM
admet-189	668	2	(	(	PUNCT
admet-189	668	3	1977	1977	NUM
admet-189	668	4	)	)	PUNCT
admet-189	668	5	409	409	NUM
admet-189	668	6	-	-	SYM
admet-189	668	7	417	417	NUM
admet-189	668	8	.	.	PUNCT
admet-189	669	1	[	[	X
admet-189	669	2	47	47	NUM
admet-189	669	3	]	]	X
admet-189	669	4	w.	w.	PROPN
admet-189	669	5	loscher	loscher	PROPN
admet-189	669	6	,	,	PUNCT
admet-189	669	7	h.	h.	PROPN
admet-189	669	8	potschka	potschka	PROPN
admet-189	669	9	,	,	PUNCT
admet-189	669	10	prog	prog	NOUN
admet-189	669	11	.	.	PUNCT
admet-189	669	12	neurobiol	neurobiol	PROPN
admet-189	669	13	.	.	PUNCT
admet-189	670	1	76	76	NUM
admet-189	670	2	(	(	PUNCT
admet-189	670	3	2005	2005	NUM
admet-189	670	4	)	)	PUNCT
admet-189	670	5	22	22	NUM
admet-189	670	6	-	-	SYM
admet-189	670	7	76	76	NUM
admet-189	670	8	.	.	PUNCT
admet-189	671	1	[	[	X
admet-189	671	2	48	48	NUM
admet-189	671	3	]	]	X
admet-189	671	4	w.m	w.m	PROPN
admet-189	671	5	.	.	PROPN
admet-189	671	6	pardridge	pardridge	PROPN
admet-189	671	7	,	,	PUNCT
admet-189	671	8	mol	mol	PROPN
admet-189	671	9	.	.	PROPN
admet-189	671	10	biotechnol	biotechnol	NOUN
admet-189	671	11	.	.	PUNCT
admet-189	672	1	30	30	NUM
admet-189	672	2	(	(	PUNCT
admet-189	672	3	2005	2005	NUM
admet-189	672	4	)	)	PUNCT
admet-189	672	5	57	57	NUM
admet-189	672	6	-	-	SYM
admet-189	672	7	70	70	NUM
admet-189	672	8	.	.	PUNCT
admet-189	673	1	[	[	X
admet-189	673	2	49	49	NUM
admet-189	673	3	]	]	X
admet-189	673	4	n.j	n.j	PROPN
admet-189	673	5	.	.	PROPN
admet-189	673	6	abbott	abbott	PROPN
admet-189	673	7	,	,	PUNCT
admet-189	673	8	a.a	a.a	PROPN
admet-189	673	9	.	.	PROPN
admet-189	673	10	patabendige	patabendige	PROPN
admet-189	673	11	,	,	PUNCT
admet-189	673	12	d.e	d.e	PROPN
admet-189	673	13	.	.	PROPN
admet-189	673	14	dolman	dolman	PROPN
admet-189	673	15	,	,	PUNCT
admet-189	673	16	s.r	s.r	PROPN
admet-189	673	17	.	.	PROPN
admet-189	673	18	yusof	yusof	PROPN
admet-189	673	19	,	,	PUNCT
admet-189	673	20	d.j	d.j	PROPN
admet-189	673	21	.	.	PROPN
admet-189	673	22	begley	begley	PROPN
admet-189	673	23	,	,	PUNCT
admet-189	673	24	neurobiol	neurobiol	PROPN
admet-189	673	25	.	.	PUNCT
admet-189	674	1	dis	dis	PROPN
admet-189	674	2	.	.	PUNCT
admet-189	675	1	37	37	NUM
admet-189	675	2	(	(	PUNCT
admet-189	675	3	2010	2010	NUM
admet-189	675	4	)	)	PUNCT
admet-189	675	5	13	13	NUM
admet-189	675	6	-	-	SYM
admet-189	675	7	25	25	NUM
admet-189	675	8	.	.	PUNCT
admet-189	676	1	[	[	X
admet-189	676	2	50	50	NUM
admet-189	676	3	]	]	PUNCT
admet-189	676	4	r.	r.	PROPN
admet-189	676	5	kortekaas	kortekaas	PROPN
admet-189	676	6	,	,	PUNCT
admet-189	676	7	k.l	k.l	PROPN
admet-189	676	8	.	.	PROPN
admet-189	676	9	leenders	leenders	PROPN
admet-189	676	10	,	,	PUNCT
admet-189	676	11	j.c	j.c	PROPN
admet-189	676	12	.	.	PROPN
admet-189	676	13	van	van	PROPN
admet-189	676	14	oostrom	oostrom	PROPN
admet-189	676	15	,	,	PUNCT
admet-189	676	16	w.	w.	NOUN
admet-189	676	17	vaalburg	vaalburg	PROPN
admet-189	676	18	,	,	PUNCT
admet-189	676	19	j.	j.	PROPN
admet-189	676	20	bart	bart	PROPN
admet-189	676	21	,	,	PUNCT
admet-189	676	22	a.t	a.t	PROPN
admet-189	676	23	.	.	PROPN
admet-189	676	24	willemsen	willemsen	PROPN
admet-189	676	25	,	,	PUNCT
admet-189	676	26	n.h	n.h	PROPN
admet-189	676	27	.	.	PROPN
admet-189	676	28	hendrikse	hendrikse	PROPN
admet-189	676	29	,	,	PUNCT
admet-189	676	30	ann	ann	PROPN
admet-189	676	31	.	.	PUNCT
admet-189	677	1	neurol	neurol	PROPN
admet-189	677	2	.	.	PUNCT
admet-189	678	1	57	57	NUM
admet-189	678	2	(	(	PUNCT
admet-189	678	3	2005	2005	NUM
admet-189	678	4	)	)	PUNCT
admet-189	678	5	176	176	NUM
admet-189	678	6	-	-	SYM
admet-189	678	7	179	179	NUM
admet-189	678	8	.	.	PUNCT
admet-189	679	1	[	[	X
admet-189	679	2	51	51	NUM
admet-189	679	3	]	]	SYM
admet-189	679	4	f.i	f.i	PROPN
admet-189	679	5	.	.	PROPN
admet-189	679	6	tarazi	tarazi	PROPN
admet-189	679	7	,	,	PUNCT
admet-189	679	8	z.t	z.t	PROPN
admet-189	679	9	.	.	PROPN
admet-189	679	10	sahli	sahli	PROPN
admet-189	679	11	,	,	PUNCT
admet-189	679	12	m.	m.	PROPN
admet-189	679	13	wolny	wolny	PROPN
admet-189	679	14	,	,	PUNCT
admet-189	679	15	s.a	s.a	PROPN
admet-189	679	16	.	.	PROPN
admet-189	679	17	mousa	mousa	PROPN
admet-189	679	18	,	,	PUNCT
admet-189	679	19	pharmacol	pharmacol	PROPN
admet-189	679	20	.	.	PUNCT
admet-189	680	1	ther	ther	PROPN
admet-189	680	2	.	.	PUNCT
admet-189	681	1	144	144	NUM
admet-189	681	2	(	(	PUNCT
admet-189	681	3	2014	2014	NUM
admet-189	681	4	)	)	PUNCT
admet-189	681	5	123	123	NUM
admet-189	681	6	-	-	SYM
admet-189	681	7	133	133	NUM
admet-189	681	8	.	.	PUNCT
admet-189	682	1	[	[	X
admet-189	682	2	52	52	NUM
admet-189	682	3	]	]	PUNCT
admet-189	682	4	w.	w.	PROPN
admet-189	682	5	schuepbach	schuepbach	PROPN
admet-189	682	6	,	,	PUNCT
admet-189	682	7	j.	j.	PROPN
admet-189	682	8	rau	rau	PROPN
admet-189	682	9	,	,	PUNCT
admet-189	682	10	k.	k.	PROPN
admet-189	682	11	knudsen	knudsen	PROPN
admet-189	682	12	,	,	PUNCT
admet-189	682	13	j.	j.	PROPN
admet-189	682	14	volkmann	volkmann	PROPN
admet-189	682	15	,	,	PUNCT
admet-189	682	16	p.	p.	PROPN
admet-189	682	17	krack	krack	NOUN
admet-189	682	18	,	,	PUNCT
admet-189	682	19	l.	l.	PROPN
admet-189	682	20	timmermann	timmermann	PROPN
admet-189	682	21	,	,	PUNCT
admet-189	682	22	t.	t.	PROPN
admet-189	682	23	hälbig	hälbig	PROPN
admet-189	682	24	,	,	PUNCT
admet-189	682	25	h.	h.	PROPN
admet-189	682	26	hesekamp	hesekamp	PROPN
admet-189	682	27	,	,	PUNCT
admet-189	682	28	s.	s.	PROPN
admet-189	682	29	navarro	navarro	PROPN
admet-189	682	30	,	,	PUNCT
admet-189	682	31	n.	n.	PROPN
admet-189	682	32	meier	meier	PROPN
admet-189	682	33	,	,	PUNCT
admet-189	682	34	n.	n.	PROPN
admet-189	682	35	eng	eng	PROPN
admet-189	682	36	.	.	PUNCT
admet-189	682	37	j.	j.	PROPN
admet-189	682	38	med	med	PROPN
admet-189	682	39	.	.	PUNCT
admet-189	683	1	368	368	NUM
admet-189	683	2	(	(	PUNCT
admet-189	683	3	2013	2013	NUM
admet-189	683	4	)	)	PUNCT
admet-189	683	5	610	610	NUM
admet-189	683	6	-	-	SYM
admet-189	683	7	622	622	NUM
admet-189	683	8	.	.	PUNCT
admet-189	684	1	[	[	X
admet-189	684	2	53	53	NUM
admet-189	684	3	]	]	PUNCT
admet-189	684	4	e.	e.	PROPN
admet-189	684	5	coley	coley	PROPN
admet-189	684	6	,	,	PUNCT
admet-189	684	7	r.	r.	PROPN
admet-189	684	8	farhadi	farhadi	PROPN
admet-189	684	9	,	,	PUNCT
admet-189	684	10	s.	s.	PROPN
admet-189	684	11	lewis	lewis	PROPN
admet-189	684	12	,	,	PUNCT
admet-189	684	13	i.r	i.r	PROPN
admet-189	684	14	.	.	PROPN
admet-189	684	15	whittle	whittle	PROPN
admet-189	684	16	,	,	PUNCT
admet-189	684	17	br	br	PROPN
admet-189	684	18	.	.	PUNCT
admet-189	685	1	j.	j.	PROPN
admet-189	685	2	neurosurg	neurosurg	PROPN
admet-189	685	3	.	.	PUNCT
admet-189	686	1	23	23	NUM
admet-189	686	2	(	(	PUNCT
admet-189	686	3	2009	2009	NUM
admet-189	686	4	)	)	PUNCT
admet-189	686	5	179	179	NUM
admet-189	686	6	-	-	SYM
admet-189	686	7	183	183	NUM
admet-189	686	8	.	.	PUNCT
admet-189	687	1	[	[	X
admet-189	687	2	54	54	NUM
admet-189	687	3	]	]	SYM
admet-189	687	4	k.a	k.a	PROPN
admet-189	687	5	.	.	PROPN
admet-189	687	6	sillay	sillay	PROPN
admet-189	687	7	,	,	PUNCT
admet-189	687	8	p.s	p.s	PROPN
admet-189	687	9	.	.	PROPN
admet-189	687	10	larson	larson	PROPN
admet-189	687	11	,	,	PUNCT
admet-189	687	12	p.a	p.a	PROPN
admet-189	687	13	.	.	PROPN
admet-189	687	14	starr	starr	PROPN
admet-189	687	15	,	,	PUNCT
admet-189	687	16	neurosurgery	neurosurgery	NOUN
admet-189	687	17	62	62	NUM
admet-189	687	18	(	(	PUNCT
admet-189	687	19	2008	2008	NUM
admet-189	687	20	)	)	PUNCT
admet-189	687	21	360	360	NUM
admet-189	687	22	-	-	SYM
admet-189	687	23	6	6	NUM
admet-189	687	24	;	;	PUNCT
admet-189	687	25	discussion	discussion	NOUN
admet-189	687	26	366	366	NUM
admet-189	687	27	-	-	SYM
admet-189	687	28	367	367	NUM
admet-189	687	29	.	.	PUNCT
admet-189	688	1	[	[	X
admet-189	688	2	55	55	NUM
admet-189	688	3	]	]	PUNCT
admet-189	688	4	e.	e.	PROPN
admet-189	688	5	martin	martin	PROPN
admet-189	688	6	,	,	PUNCT
admet-189	688	7	d.	d.	PROPN
admet-189	688	8	jeanmonod	jeanmonod	PROPN
admet-189	688	9	,	,	PUNCT
admet-189	688	10	a.	a.	NOUN
admet-189	688	11	morel	morel	PROPN
admet-189	688	12	,	,	PUNCT
admet-189	688	13	e.	e.	PROPN
admet-189	688	14	zadicario	zadicario	PROPN
admet-189	688	15	,	,	PUNCT
admet-189	688	16	b.	b.	PROPN
admet-189	688	17	werner	werner	PROPN
admet-189	688	18	,	,	PUNCT
admet-189	688	19	ann	ann	PROPN
admet-189	688	20	.	.	PUNCT
admet-189	688	21	neurol	neurol	PROPN
admet-189	688	22	.	.	PUNCT
admet-189	689	1	66	66	NUM
admet-189	689	2	(	(	PUNCT
admet-189	689	3	2009	2009	NUM
admet-189	689	4	)	)	PUNCT
admet-189	689	5	858	858	NUM
admet-189	689	6	-	-	SYM
admet-189	689	7	861	861	NUM
admet-189	689	8	.	.	PUNCT
admet-189	690	1	[	[	X
admet-189	690	2	56	56	NUM
admet-189	690	3	]	]	X
admet-189	690	4	c.	c.	NOUN
admet-189	690	5	ohye	ohye	NOUN
admet-189	690	6	,	,	PUNCT
admet-189	690	7	y.	y.	PROPN
admet-189	690	8	higuchi	higuchi	PROPN
admet-189	690	9	,	,	PUNCT
admet-189	690	10	t.	t.	NOUN
admet-189	690	11	shibazaki	shibazaki	NOUN
admet-189	690	12	,	,	PUNCT
admet-189	690	13	t.	t.	NOUN
admet-189	690	14	hashimoto	hashimoto	NOUN
admet-189	690	15	,	,	PUNCT
admet-189	690	16	t.	t.	PROPN
admet-189	690	17	koyama	koyama	PROPN
admet-189	690	18	,	,	PUNCT
admet-189	690	19	t.	t.	NOUN
admet-189	690	20	hirai	hirai	PROPN
admet-189	690	21	,	,	PUNCT
admet-189	690	22	s.	s.	PROPN
admet-189	690	23	matsuda	matsuda	PROPN
admet-189	690	24	,	,	PUNCT
admet-189	690	25	t.	t.	PROPN
admet-189	690	26	serizawa	serizawa	PROPN
admet-189	690	27	,	,	PUNCT
admet-189	690	28	t.	t.	PROPN
admet-189	690	29	hori	hori	PROPN
admet-189	690	30	,	,	PUNCT
admet-189	690	31	m.	m.	PROPN
admet-189	690	32	hayashi	hayashi	PROPN
admet-189	690	33	,	,	PUNCT
admet-189	690	34	t.	t.	PROPN
admet-189	690	35	ochiai	ochiai	PROPN
admet-189	690	36	,	,	PUNCT
admet-189	690	37	h.	h.	PROPN
admet-189	690	38	samura	samura	PROPN
admet-189	690	39	,	,	PUNCT
admet-189	690	40	k.	k.	PROPN
admet-189	690	41	yamashiro	yamashiro	PROPN
admet-189	690	42	,	,	PUNCT
admet-189	690	43	neurosurgery	neurosurgery	NOUN
admet-189	690	44	70	70	NUM
admet-189	690	45	(	(	PUNCT
admet-189	690	46	2012	2012	NUM
admet-189	690	47	)	)	PUNCT
admet-189	690	48	526	526	NUM
admet-189	690	49	-	-	SYM
admet-189	690	50	535	535	NUM
admet-189	690	51	;	;	PUNCT
admet-189	690	52	discussion	discussion	NOUN
admet-189	690	53	535536	535536	NUM
admet-189	690	54	.	.	PUNCT
admet-189	691	1	[	[	X
admet-189	691	2	57	57	NUM
admet-189	691	3	]	]	PUNCT
admet-189	691	4	royal	royal	ADJ
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admet-189	691	6	,	,	PUNCT
admet-189	691	7	royal	royal	PROPN
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admet-189	691	9	of	of	ADP
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admet-189	691	11	,	,	PUNCT
admet-189	691	12	nanoscience	nanoscience	NOUN
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admet-189	691	14	nanotechnologies	nanotechnology	NOUN
admet-189	691	15	:	:	PUNCT
admet-189	691	16	opportunities	opportunity	NOUN
admet-189	691	17	and	and	CCONJ
admet-189	691	18	uncertainties	uncertainty	NOUN
admet-189	691	19	,	,	PUNCT
admet-189	691	20	royal	royal	ADJ
admet-189	691	21	society	society	NOUN
admet-189	691	22	,	,	PUNCT
admet-189	691	23	2004	2004	NUM
admet-189	691	24	.	.	PUNCT
admet-189	692	1	[	[	X
admet-189	692	2	58	58	NUM
admet-189	692	3	]	]	X
admet-189	692	4	w.g	w.g	PROPN
admet-189	692	5	.	.	PROPN
admet-189	692	6	meissner	meissner	PROPN
admet-189	692	7	,	,	PUNCT
admet-189	692	8	m.	m.	NOUN
admet-189	692	9	frasier	frasier	PROPN
admet-189	692	10	,	,	PUNCT
admet-189	692	11	t.	t.	NOUN
admet-189	692	12	gasser	gasser	NOUN
admet-189	692	13	,	,	PUNCT
admet-189	692	14	c.g	c.g	PROPN
admet-189	692	15	.	.	PROPN
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admet-189	692	17	,	,	PUNCT
admet-189	692	18	a.	a.	PROPN
admet-189	692	19	lozano	lozano	PROPN
admet-189	692	20	,	,	PUNCT
admet-189	692	21	p.	p.	NOUN
admet-189	692	22	piccini	piccini	PROPN
admet-189	692	23	,	,	PUNCT
admet-189	692	24	j.a	j.a	PROPN
admet-189	692	25	.	.	PROPN
admet-189	692	26	obeso	obeso	NOUN
admet-189	692	27	,	,	PUNCT
admet-189	692	28	o.	o.	NOUN
admet-189	692	29	rascol	rascol	PROPN
admet-189	692	30	,	,	PUNCT
admet-189	692	31	a.	a.	NOUN
admet-189	692	32	schapira	schapira	NOUN
admet-189	692	33	,	,	PUNCT
admet-189	692	34	v.	v.	PROPN
admet-189	692	35	voon	voon	PROPN
admet-189	692	36	,	,	PUNCT
admet-189	692	37	d.m	d.m	PROPN
admet-189	692	38	.	.	PUNCT
admet-189	692	39	weiner	weiner	NOUN
admet-189	692	40	,	,	PUNCT
admet-189	692	41	f.	f.	PROPN
admet-189	692	42	tison	tison	PROPN
admet-189	692	43	,	,	PUNCT
admet-189	692	44	e.	e.	PROPN
admet-189	692	45	bezard	bezard	PROPN
admet-189	692	46	,	,	PUNCT
admet-189	692	47	nat	nat	PROPN
admet-189	692	48	.	.	PUNCT
admet-189	692	49	rev	rev	PROPN
admet-189	692	50	.	.	PROPN
admet-189	692	51	drug	drug	NOUN
admet-189	692	52	discov	discov	NOUN
admet-189	692	53	.	.	PUNCT
admet-189	693	1	10	10	NUM
admet-189	693	2	(	(	PUNCT
admet-189	693	3	2011	2011	NUM
admet-189	693	4	)	)	PUNCT
admet-189	693	5	377	377	NUM
admet-189	693	6	-	-	SYM
admet-189	693	7	393	393	NUM
admet-189	693	8	.	.	PUNCT
admet-189	694	1	[	[	X
admet-189	694	2	59	59	NUM
admet-189	694	3	]	]	PUNCT
admet-189	694	4	s.	s.	PROPN
admet-189	694	5	sharma	sharma	PROPN
admet-189	694	6	,	,	PUNCT
admet-189	694	7	c.s	c.s	PROPN
admet-189	694	8	.	.	PROPN
admet-189	694	9	moon	moon	PROPN
admet-189	694	10	,	,	PUNCT
admet-189	694	11	a.	a.	PROPN
admet-189	694	12	khogali	khogali	PROPN
admet-189	694	13	,	,	PUNCT
admet-189	694	14	a.	a.	PROPN
admet-189	694	15	haidous	haidous	PROPN
admet-189	694	16	,	,	PUNCT
admet-189	694	17	a.	a.	NOUN
admet-189	694	18	chabenne	chabenne	NOUN
admet-189	694	19	,	,	PUNCT
admet-189	694	20	c.	c.	PROPN
admet-189	694	21	ojo	ojo	PROPN
admet-189	694	22	,	,	PUNCT
admet-189	694	23	m.	m.	NOUN
admet-189	694	24	jelebinkov	jelebinkov	PROPN
admet-189	694	25	,	,	PUNCT
admet-189	694	26	y.	y.	PROPN
admet-189	694	27	kurdi	kurdi	PROPN
admet-189	694	28	,	,	PUNCT
admet-189	694	29	m.	m.	NOUN
admet-189	694	30	ebadi	ebadi	NOUN
admet-189	694	31	,	,	PUNCT
admet-189	694	32	neurochem	neurochem	PROPN
admet-189	694	33	.	.	PUNCT
admet-189	695	1	inter	inter	PROPN
admet-189	695	2	.	.	PUNCT
admet-189	696	1	63	63	NUM
admet-189	696	2	(	(	PUNCT
admet-189	696	3	2013	2013	NUM
admet-189	696	4	)	)	PUNCT
admet-189	696	5	201	201	NUM
admet-189	696	6	-	-	SYM
admet-189	696	7	229	229	NUM
admet-189	696	8	.	.	PUNCT
admet-189	697	1	[	[	X
admet-189	697	2	60	60	NUM
admet-189	697	3	]	]	PUNCT
admet-189	697	4	j.	j.	PROPN
admet-189	697	5	tashkhourian	tashkhourian	PROPN
admet-189	697	6	,	,	PUNCT
admet-189	697	7	m.r.h	m.r.h	PROPN
admet-189	697	8	.	.	PROPN
admet-189	697	9	nezhad	nezhad	PROPN
admet-189	697	10	,	,	PUNCT
admet-189	697	11	j.	j.	PROPN
admet-189	697	12	khodavesi	khodavesi	PROPN
admet-189	697	13	,	,	PUNCT
admet-189	697	14	s.	s.	PROPN
admet-189	697	15	javadi	javadi	PROPN
admet-189	697	16	,	,	PUNCT
admet-189	697	17	j.	j.	PROPN
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admet-189	697	19	.	.	PUNCT
admet-189	698	1	chem	chem	PROPN
admet-189	698	2	.	.	PUNCT
admet-189	699	1	633	633	NUM
admet-189	699	2	(	(	PUNCT
admet-189	699	3	2009	2009	NUM
admet-189	699	4	)	)	PUNCT
admet-189	699	5	85	85	NUM
admet-189	699	6	-	-	SYM
admet-189	699	7	91	91	NUM
admet-189	699	8	.	.	PUNCT
admet-189	700	1	[	[	X
admet-189	700	2	61	61	NUM
admet-189	700	3	]	]	SYM
admet-189	700	4	h.y	h.y	PROPN
admet-189	700	5	.	.	PROPN
admet-189	700	6	yue	yue	PROPN
admet-189	700	7	,	,	PUNCT
admet-189	700	8	s.	s.	PROPN
admet-189	700	9	huang	huang	PROPN
admet-189	700	10	,	,	PUNCT
admet-189	700	11	j.	j.	PROPN
admet-189	700	12	chang	chang	PROPN
admet-189	700	13	,	,	PUNCT
admet-189	700	14	c.	c.	PROPN
admet-189	700	15	heo	heo	PROPN
admet-189	700	16	,	,	PUNCT
admet-189	700	17	f.	f.	PROPN
admet-189	700	18	yao	yao	PROPN
admet-189	700	19	,	,	PUNCT
admet-189	700	20	s.	s.	PROPN
admet-189	700	21	adhikari	adhikari	PROPN
admet-189	700	22	,	,	PUNCT
admet-189	700	23	f.	f.	PROPN
admet-189	700	24	gunes	gunes	PROPN
admet-189	700	25	,	,	PUNCT
admet-189	700	26	l.c	l.c	PROPN
admet-189	700	27	.	.	PROPN
admet-189	700	28	liu	liu	PROPN
admet-189	700	29	,	,	PUNCT
admet-189	700	30	t.h	t.h	PROPN
admet-189	700	31	.	.	PROPN
admet-189	700	32	lee	lee	PROPN
admet-189	700	33	,	,	PUNCT
admet-189	700	34	e.s	e.s	PROPN
admet-189	700	35	.	.	PROPN
admet-189	700	36	oh	oh	INTJ
admet-189	700	37	,	,	PUNCT
admet-189	700	38	b.	b.	PROPN
admet-189	700	39	li	li	PROPN
admet-189	700	40	,	,	PUNCT
admet-189	700	41	j.j	j.j	PROPN
admet-189	700	42	.	.	PROPN
admet-189	700	43	zhang	zhang	PROPN
admet-189	700	44	,	,	PUNCT
admet-189	700	45	t.q	t.q	PROPN
admet-189	700	46	.	.	PROPN
admet-189	700	47	huy	huy	PROPN
admet-189	700	48	,	,	PUNCT
admet-189	700	49	n.v	n.v	PROPN
admet-189	700	50	.	.	PROPN
admet-189	700	51	luan	luan	PROPN
admet-189	700	52	,	,	PUNCT
admet-189	700	53	y.h	y.h	PROPN
admet-189	700	54	.	.	PROPN
admet-189	700	55	lee	lee	PROPN
admet-189	700	56	,	,	PUNCT
admet-189	700	57	acs	acs	PROPN
admet-189	700	58	nano	nano	VERB
admet-189	700	59	8	8	NUM
admet-189	700	60	(	(	PUNCT
admet-189	700	61	2014	2014	NUM
admet-189	700	62	)	)	PUNCT
admet-189	700	63	1639	1639	NUM
admet-189	700	64	-	-	SYM
admet-189	700	65	1646	1646	NUM
admet-189	700	66	.	.	PUNCT
admet-189	701	1	[	[	X
admet-189	701	2	62	62	NUM
admet-189	701	3	]	]	PUNCT
admet-189	701	4	k.	k.	PROPN
admet-189	701	5	kurzatkowska	kurzatkowska	PROPN
admet-189	701	6	,	,	PUNCT
admet-189	701	7	e.	e.	PROPN
admet-189	701	8	dolusic	dolusic	PROPN
admet-189	701	9	,	,	PUNCT
admet-189	701	10	w.	w.	PROPN
admet-189	701	11	dehaen	dehaen	PROPN
admet-189	701	12	,	,	PUNCT
admet-189	701	13	k.	k.	PROPN
admet-189	701	14	sieroń	sieroń	PROPN
admet-189	701	15	-	-	PUNCT
admet-189	701	16	stołtny	stołtny	NOUN
admet-189	701	17	,	,	PUNCT
admet-189	701	18	a.	a.	NOUN
admet-189	701	19	sieroń	sieroń	PROPN
admet-189	701	20	,	,	PUNCT
admet-189	701	21	h.	h.	PROPN
admet-189	701	22	radecka	radecka	PROPN
admet-189	701	23	,	,	PUNCT
admet-189	701	24	anal	anal	PROPN
admet-189	701	25	.	.	PUNCT
admet-189	702	1	chem	chem	PROPN
admet-189	702	2	.	.	PUNCT
admet-189	703	1	81	81	NUM
admet-189	703	2	(	(	PUNCT
admet-189	703	3	2009	2009	NUM
admet-189	703	4	)	)	PUNCT
admet-189	703	5	7397	7397	NUM
admet-189	703	6	-	-	SYM
admet-189	703	7	7405	7405	NUM
admet-189	703	8	.	.	PUNCT
admet-189	704	1	[	[	X
admet-189	704	2	63	63	NUM
admet-189	704	3	]	]	PUNCT
admet-189	704	4	w.	w.	PROPN
admet-189	704	5	ma	ma	PROPN
admet-189	704	6	,	,	PUNCT
admet-189	704	7	l.-x	l.-x	PROPN
admet-189	704	8	.	.	PUNCT
admet-189	705	1	qin	qin	PROPN
admet-189	705	2	,	,	PUNCT
admet-189	705	3	f.-t	f.-t	NOUN
admet-189	705	4	.	.	PUNCT
admet-189	706	1	liu	liu	PROPN
admet-189	706	2	,	,	PUNCT
admet-189	706	3	z.	z.	PROPN
admet-189	706	4	gu	gu	PROPN
admet-189	706	5	,	,	PUNCT
admet-189	706	6	j.	j.	PROPN
admet-189	706	7	wang	wang	PROPN
admet-189	706	8	,	,	PUNCT
admet-189	706	9	z.g	z.g	PROPN
admet-189	706	10	.	.	PROPN
admet-189	706	11	pan	pan	PROPN
admet-189	706	12	,	,	PUNCT
admet-189	706	13	t.d	t.d	PROPN
admet-189	706	14	.	.	PROPN
admet-189	706	15	james	james	PROPN
admet-189	706	16	,	,	PUNCT
admet-189	706	17	y.-t	y.-t	NOUN
admet-189	706	18	.	.	PUNCT
admet-189	707	1	long	long	ADV
admet-189	707	2	,	,	PUNCT
admet-189	707	3	sci	sci	PROPN
admet-189	707	4	.	.	PROPN
admet-189	707	5	rep	rep	PROPN
admet-189	707	6	.	.	PROPN
admet-189	707	7	3	3	NUM
admet-189	707	8	(	(	PUNCT
admet-189	707	9	2013	2013	NUM
admet-189	707	10	)	)	PUNCT
admet-189	707	11	1537	1537	NUM
admet-189	707	12	.	.	PUNCT
admet-189	708	1	[	[	X
admet-189	708	2	64	64	NUM
admet-189	708	3	]	]	X
admet-189	708	4	y.	y.	PROPN
admet-189	708	5	an	an	PROPN
admet-189	708	6	,	,	PUNCT
admet-189	708	7	l.	l.	PROPN
admet-189	708	8	tang	tang	PROPN
admet-189	708	9	,	,	PUNCT
admet-189	708	10	x.	x.	PROPN
admet-189	708	11	jiang	jiang	PROPN
admet-189	708	12	,	,	PUNCT
admet-189	708	13	h.	h.	PROPN
admet-189	708	14	chen	chen	PROPN
admet-189	708	15	,	,	PUNCT
admet-189	708	16	m.	m.	PROPN
admet-189	708	17	yang	yang	PROPN
admet-189	708	18	,	,	PUNCT
admet-189	708	19	l.	l.	PROPN
admet-189	708	20	jin	jin	PROPN
admet-189	708	21	,	,	PUNCT
admet-189	708	22	s.	s.	PROPN
admet-189	708	23	zhang	zhang	PROPN
admet-189	708	24	,	,	PUNCT
admet-189	708	25	c.	c.	PROPN
admet-189	708	26	wang	wang	PROPN
admet-189	708	27	,	,	PUNCT
admet-189	708	28	w.	w.	PROPN
admet-189	708	29	zhang	zhang	PROPN
admet-189	708	30	,	,	PUNCT
admet-189	708	31	chem	chem	PROPN
admet-189	708	32	.	.	PUNCT
admet-189	709	1	eur	eur	PROPN
admet-189	709	2	.	.	PUNCT
admet-189	710	1	j.	j.	PROPN
admet-189	710	2	16	16	NUM
admet-189	710	3	(	(	PUNCT
admet-189	710	4	2010	2010	NUM
admet-189	710	5	)	)	PUNCT
admet-189	710	6	14439	14439	NUM
admet-189	710	7	-	-	SYM
admet-189	710	8	14446	14446	NUM
admet-189	710	9	.	.	PUNCT
admet-189	711	1	[	[	X
admet-189	711	2	65	65	NUM
admet-189	711	3	]	]	X
admet-189	711	4	y.y	y.y	PROPN
admet-189	711	5	.	.	PROPN
admet-189	711	6	broza	broza	PROPN
admet-189	711	7	,	,	PUNCT
admet-189	711	8	h.	h.	PROPN
admet-189	711	9	haick	haick	PROPN
admet-189	711	10	,	,	PUNCT
admet-189	711	11	nanomedicine	nanomedicine	NOUN
admet-189	711	12	(	(	PUNCT
admet-189	711	13	lond	lond	ADJ
admet-189	711	14	)	)	PUNCT
admet-189	711	15	8	8	NUM
admet-189	711	16	(	(	PUNCT
admet-189	711	17	2013	2013	NUM
admet-189	711	18	)	)	PUNCT
admet-189	711	19	785	785	NUM
admet-189	711	20	-	-	SYM
admet-189	711	21	806	806	NUM
admet-189	711	22	.	.	PUNCT
admet-189	712	1	[	[	X
admet-189	712	2	66	66	NUM
admet-189	712	3	]	]	X
admet-189	712	4	u.	u.	PROPN
admet-189	712	5	tisch	tisch	PROPN
admet-189	712	6	,	,	PUNCT
admet-189	712	7	i.	i.	PROPN
admet-189	712	8	schlesinger	schlesinger	PROPN
admet-189	712	9	,	,	PUNCT
admet-189	712	10	r.	r.	PROPN
admet-189	712	11	ionescu	ionescu	PROPN
admet-189	712	12	,	,	PUNCT
admet-189	712	13	m.	m.	NOUN
admet-189	712	14	nassar	nassar	PROPN
admet-189	712	15	,	,	PUNCT
admet-189	712	16	n.	n.	PROPN
admet-189	712	17	axelrod	axelrod	PROPN
admet-189	712	18	,	,	PUNCT
admet-189	712	19	d.	d.	PROPN
admet-189	712	20	robertman	robertman	PROPN
admet-189	712	21	,	,	PUNCT
admet-189	712	22	y.	y.	PROPN
admet-189	712	23	tessler	tessler	PROPN
admet-189	712	24	,	,	PUNCT
admet-189	712	25	f.	f.	PROPN
admet-189	712	26	azar	azar	PROPN
admet-189	712	27	,	,	PUNCT
admet-189	712	28	a.	a.	PROPN
admet-189	712	29	marmur	marmur	PROPN
admet-189	712	30	,	,	PUNCT
admet-189	712	31	j.	j.	PROPN
admet-189	712	32	aharon	aharon	PROPN
admet-189	712	33	-	-	PUNCT
admet-189	712	34	peretz	peretz	PROPN
admet-189	712	35	,	,	PUNCT
admet-189	712	36	h.	h.	PROPN
admet-189	712	37	haick	haick	PROPN
admet-189	712	38	,	,	PUNCT
admet-189	712	39	nanomedicine	nanomedicine	NOUN
admet-189	712	40	(	(	PUNCT
admet-189	712	41	lond	lond	ADJ
admet-189	712	42	)	)	PUNCT
admet-189	712	43	8	8	NUM
admet-189	712	44	(	(	PUNCT
admet-189	712	45	2013	2013	NUM
admet-189	712	46	)	)	PUNCT
admet-189	712	47	43	43	NUM
admet-189	712	48	-	-	SYM
admet-189	712	49	56	56	NUM
admet-189	712	50	.	.	PUNCT
admet-189	713	1	[	[	X
admet-189	713	2	67	67	NUM
admet-189	713	3	]	]	X
admet-189	713	4	r.	r.	PROPN
admet-189	713	5	ortega	ortega	PROPN
admet-189	713	6	,	,	PUNCT
admet-189	713	7	p.	p.	NOUN
admet-189	713	8	cloetens	cloetens	PROPN
admet-189	713	9	,	,	PUNCT
admet-189	713	10	g.	g.	PROPN
admet-189	713	11	devès	devès	PROPN
admet-189	713	12	,	,	PUNCT
admet-189	713	13	a.	a.	PROPN
admet-189	713	14	carmona	carmona	PROPN
admet-189	713	15	,	,	PUNCT
admet-189	713	16	s.	s.	PROPN
admet-189	713	17	bohic	bohic	PROPN
admet-189	713	18	,	,	PUNCT
admet-189	713	19	plos	plos	PROPN
admet-189	713	20	one	one	NUM
admet-189	713	21	2	2	NUM
admet-189	713	22	(	(	PUNCT
admet-189	713	23	2007	2007	NUM
admet-189	713	24	)	)	PUNCT
admet-189	713	25	e925	e925	PROPN
admet-189	713	26	.	.	PUNCT
admet-189	714	1	[	[	X
admet-189	714	2	68	68	NUM
admet-189	714	3	]	]	PUNCT
admet-189	714	4	x.	x.	PROPN
admet-189	714	5	wang	wang	PROPN
admet-189	714	6	,	,	PUNCT
admet-189	714	7	g.	g.	PROPN
admet-189	714	8	cui	cui	PROPN
admet-189	714	9	,	,	PUNCT
admet-189	714	10	x.	x.	PROPN
admet-189	714	11	yang	yang	PROPN
admet-189	714	12	,	,	PUNCT
admet-189	714	13	z.	z.	PROPN
admet-189	714	14	zhang	zhang	PROPN
admet-189	714	15	,	,	PUNCT
admet-189	714	16	h.	h.	PROPN
admet-189	714	17	shi	shi	PROPN
admet-189	714	18	,	,	PUNCT
admet-189	714	19	j.	j.	PROPN
admet-189	714	20	zu	zu	PROPN
admet-189	714	21	,	,	PUNCT
admet-189	714	22	f.	f.	PROPN
admet-189	714	23	hua	hua	PROPN
admet-189	714	24	,	,	PUNCT
admet-189	714	25	x.	x.	PROPN
admet-189	714	26	shen	shen	PROPN
admet-189	714	27	,	,	PUNCT
admet-189	714	28	brain	brain	NOUN
admet-189	714	29	res	re	NOUN
admet-189	714	30	.	.	PUNCT
admet-189	715	1	bull	bull	NOUN
admet-189	715	2	.	.	PUNCT
admet-189	716	1	103	103	NUM
admet-189	716	2	(	(	PUNCT
admet-189	716	3	2014	2014	NUM
admet-189	716	4	)	)	PUNCT
admet-189	716	5	60	60	NUM
admet-189	716	6	-	-	SYM
admet-189	716	7	65	65	NUM
admet-189	716	8	.	.	PUNCT
admet-189	717	1	admet	admet	PROPN
admet-189	717	2	&	&	CCONJ
admet-189	717	3	dmpk	dmpk	PROPN
admet-189	717	4	3(3	3(3	NUM
admet-189	717	5	)	)	PUNCT
admet-189	717	6	(	(	PUNCT
admet-189	717	7	2015	2015	NUM
admet-189	717	8	)	)	PUNCT
admet-189	717	9	155	155	NUM
admet-189	717	10	-	-	SYM
admet-189	717	11	181	181	NUM
admet-189	717	12	nanotechnology	nanotechnology	NOUN
admet-189	717	13	platforms	platform	NOUN
admet-189	717	14	in	in	ADP
admet-189	717	15	parkinson	parkinson	NOUN
admet-189	717	16	’s	’s	PART
admet-189	717	17	disease	disease	NOUN
admet-189	717	18	doi	doi	NOUN
admet-189	717	19	:	:	PUNCT
admet-189	717	20	10.5599	10.5599	NUM
admet-189	717	21	/	/	SYM
admet-189	717	22	admet.3.3.189	admet.3.3.189	ADP
admet-189	717	23	179	179	NUM
admet-189	717	24	[	[	X
admet-189	717	25	69	69	NUM
admet-189	717	26	]	]	PUNCT
admet-189	717	27	b.	b.	PROPN
admet-189	717	28	geers	geers	PROPN
admet-189	717	29	,	,	PUNCT
admet-189	717	30	i.	i.	PROPN
admet-189	717	31	lentacker	lentacker	PROPN
admet-189	717	32	,	,	PUNCT
admet-189	717	33	n.n	n.n	PROPN
admet-189	717	34	.	.	PROPN
admet-189	717	35	sanders	sanders	PROPN
admet-189	717	36	,	,	PUNCT
admet-189	717	37	j.	j.	PROPN
admet-189	717	38	demeester	demeester	PROPN
admet-189	717	39	,	,	PUNCT
admet-189	717	40	s.	s.	PROPN
admet-189	717	41	meairs	meairs	PROPN
admet-189	717	42	,	,	PUNCT
admet-189	717	43	s.c	s.c	PROPN
admet-189	717	44	.	.	PROPN
admet-189	717	45	de	de	X
admet-189	717	46	smedt	smedt	PROPN
admet-189	717	47	,	,	PUNCT
admet-189	717	48	j.control	j.control	NOUN
admet-189	717	49	.	.	PUNCT
admet-189	718	1	release	release	VERB
admet-189	718	2	152	152	NUM
admet-189	718	3	(	(	PUNCT
admet-189	718	4	2011	2011	NUM
admet-189	718	5	)	)	PUNCT
admet-189	718	6	249	249	NUM
admet-189	718	7	-	-	SYM
admet-189	718	8	256	256	NUM
admet-189	718	9	.	.	PUNCT
admet-189	719	1	[	[	X
admet-189	719	2	70	70	NUM
admet-189	719	3	]	]	X
admet-189	719	4	o.	o.	PROPN
admet-189	719	5	veiseh	veiseh	PROPN
admet-189	719	6	,	,	PUNCT
admet-189	719	7	j.w	j.w	PROPN
admet-189	719	8	.	.	PROPN
admet-189	719	9	gunn	gunn	PROPN
admet-189	719	10	,	,	PUNCT
admet-189	719	11	m.	m.	PROPN
admet-189	719	12	zhang	zhang	PROPN
admet-189	719	13	,	,	PUNCT
admet-189	719	14	adv	adv	PROPN
admet-189	719	15	.	.	PUNCT
admet-189	719	16	drug	drug	PROPN
admet-189	719	17	deliv	deliv	PROPN
admet-189	719	18	.	.	PUNCT
admet-189	720	1	rev	rev	PROPN
admet-189	720	2	.	.	PROPN
admet-189	720	3	62	62	NUM
admet-189	720	4	(	(	PUNCT
admet-189	720	5	2010	2010	NUM
admet-189	720	6	)	)	PUNCT
admet-189	720	7	284	284	NUM
admet-189	720	8	-	-	SYM
admet-189	720	9	304	304	NUM
admet-189	720	10	.	.	PUNCT
admet-189	721	1	[	[	X
admet-189	721	2	71	71	NUM
admet-189	721	3	]	]	X
admet-189	721	4	p.	p.	NOUN
admet-189	721	5	damier	damier	NOUN
admet-189	721	6	,	,	PUNCT
admet-189	721	7	e.c	e.c	PROPN
admet-189	721	8	.	.	PROPN
admet-189	721	9	hirsch	hirsch	PROPN
admet-189	721	10	,	,	PUNCT
admet-189	721	11	y.	y.	PROPN
admet-189	721	12	agid	agid	PROPN
admet-189	721	13	,	,	PUNCT
admet-189	721	14	a.m.	a.m.	NOUN
admet-189	721	15	graybiel	graybiel	NOUN
admet-189	721	16	,	,	PUNCT
admet-189	721	17	brain	brain	NOUN
admet-189	721	18	,	,	PUNCT
admet-189	721	19	122(pt	122(pt	NUM
admet-189	721	20	8)	8)	NUM
admet-189	721	21	(	(	PUNCT
admet-189	721	22	1999	1999	NUM
admet-189	721	23	)	)	PUNCT
admet-189	721	24	1437	1437	NUM
admet-189	721	25	-	-	SYM
admet-189	721	26	1448	1448	NUM
admet-189	721	27	.	.	PUNCT
admet-189	722	1	[	[	X
admet-189	722	2	72	72	NUM
admet-189	722	3	]	]	X
admet-189	722	4	d.	d.	PROPN
admet-189	722	5	son	son	PROPN
admet-189	722	6	,	,	PUNCT
admet-189	722	7	j.	j.	PROPN
admet-189	722	8	lee	lee	PROPN
admet-189	722	9	,	,	PUNCT
admet-189	722	10	s.	s.	PROPN
admet-189	722	11	qiao	qiao	PROPN
admet-189	722	12	,	,	PUNCT
admet-189	722	13	r.	r.	PROPN
admet-189	722	14	ghaffari	ghaffari	PROPN
admet-189	722	15	,	,	PUNCT
admet-189	722	16	j.	j.	PROPN
admet-189	722	17	kim	kim	PROPN
admet-189	722	18	,	,	PUNCT
admet-189	722	19	j.e	j.e	PROPN
admet-189	722	20	.	.	PROPN
admet-189	722	21	lee	lee	PROPN
admet-189	722	22	,	,	PUNCT
admet-189	722	23	c.	c.	PROPN
admet-189	722	24	song	song	PROPN
admet-189	722	25	,	,	PUNCT
admet-189	722	26	s.j	s.j	PROPN
admet-189	722	27	.	.	PROPN
admet-189	722	28	kim	kim	PROPN
admet-189	722	29	,	,	PUNCT
admet-189	722	30	d.j	d.j	PROPN
admet-189	722	31	.	.	PROPN
admet-189	722	32	lee	lee	PROPN
admet-189	722	33	,	,	PUNCT
admet-189	722	34	s.w	s.w	PROPN
admet-189	722	35	.	.	PROPN
admet-189	722	36	jun	jun	PROPN
admet-189	722	37	,	,	PUNCT
admet-189	722	38	s.	s.	PROPN
admet-189	722	39	yang	yang	PROPN
admet-189	722	40	,	,	PUNCT
admet-189	722	41	m.	m.	NOUN
admet-189	722	42	park	park	PROPN
admet-189	722	43	,	,	PUNCT
admet-189	722	44	j.	j.	PROPN
admet-189	722	45	shin	shin	PROPN
admet-189	722	46	,	,	PUNCT
admet-189	722	47	k.	k.	PROPN
admet-189	722	48	do	do	PROPN
admet-189	722	49	,	,	PUNCT
admet-189	722	50	m.	m.	PROPN
admet-189	722	51	lee	lee	PROPN
admet-189	722	52	,	,	PUNCT
admet-189	722	53	k.	k.	PROPN
admet-189	722	54	kang	kang	PROPN
admet-189	722	55	,	,	PUNCT
admet-189	722	56	c.s	c.s	PROPN
admet-189	722	57	.	.	PROPN
admet-189	722	58	hwang	hwang	PROPN
admet-189	722	59	,	,	PUNCT
admet-189	722	60	n.	n.	PROPN
admet-189	722	61	lu	lu	PROPN
admet-189	722	62	,	,	PUNCT
admet-189	722	63	t.	t.	PROPN
admet-189	722	64	hyeon	hyeon	PROPN
admet-189	722	65	,	,	PUNCT
admet-189	722	66	d.h	d.h	PROPN
admet-189	722	67	.	.	PROPN
admet-189	722	68	kim	kim	PROPN
admet-189	722	69	,	,	PUNCT
admet-189	722	70	nat	nat	PROPN
admet-189	722	71	.	.	PUNCT
admet-189	723	1	nanotechnol	nanotechnol	NOUN
admet-189	723	2	.	.	PUNCT
admet-189	724	1	9	9	NUM
admet-189	724	2	(	(	PUNCT
admet-189	724	3	2014	2014	NUM
admet-189	724	4	)	)	PUNCT
admet-189	724	5	397	397	NUM
admet-189	724	6	-	-	SYM
admet-189	724	7	404	404	NUM
admet-189	724	8	.	.	PUNCT
admet-189	725	1	[	[	X
admet-189	725	2	73	73	NUM
admet-189	725	3	]	]	X
admet-189	725	4	r.c	r.c	PROPN
admet-189	725	5	.	.	PROPN
admet-189	725	6	zietsma	zietsma	PROPN
admet-189	725	7	,	,	PUNCT
admet-189	725	8	(	(	PUNCT
admet-189	725	9	manus	manus	PROPN
admet-189	725	10	neurodynamica	neurodynamica	PROPN
admet-189	725	11	ltd	ltd	PROPN
admet-189	725	12	)	)	PUNCT
admet-189	725	13	,	,	PUNCT
admet-189	725	14	wo	will	AUX
admet-189	725	15	2011141734	2011141734	NUM
admet-189	725	16	a1	a1	NOUN
admet-189	725	17	(	(	PUNCT
admet-189	725	18	2011	2011	NUM
admet-189	725	19	)	)	PUNCT
admet-189	725	20	.	.	PUNCT
admet-189	726	1	[	[	X
admet-189	726	2	74	74	NUM
admet-189	726	3	]	]	PUNCT
admet-189	726	4	f.	f.	PROPN
admet-189	726	5	schlachetzki	schlachetzki	PROPN
admet-189	726	6	,	,	PUNCT
admet-189	726	7	y.	y.	PROPN
admet-189	726	8	zhang	zhang	PROPN
admet-189	726	9	,	,	PUNCT
admet-189	726	10	r.j	r.j	PROPN
admet-189	726	11	.	.	PROPN
admet-189	726	12	boado	boado	PROPN
admet-189	726	13	,	,	PUNCT
admet-189	726	14	w.m	w.m	PROPN
admet-189	726	15	.	.	PROPN
admet-189	726	16	pardridge	pardridge	PROPN
admet-189	726	17	,	,	PUNCT
admet-189	726	18	neurology	neurology	NOUN
admet-189	726	19	62	62	NUM
admet-189	726	20	(	(	PUNCT
admet-189	726	21	2004	2004	NUM
admet-189	726	22	)	)	PUNCT
admet-189	726	23	1275	1275	NUM
admet-189	726	24	-	-	SYM
admet-189	726	25	1281	1281	NUM
admet-189	726	26	.	.	PUNCT
admet-189	727	1	[	[	X
admet-189	727	2	75	75	NUM
admet-189	727	3	]	]	X
admet-189	727	4	w.m	w.m	PROPN
admet-189	727	5	.	.	PROPN
admet-189	727	6	pardridge	pardridge	PROPN
admet-189	727	7	,	,	PUNCT
admet-189	727	8	curr	curr	PROPN
admet-189	727	9	.	.	PUNCT
admet-189	728	1	opin	opin	NOUN
admet-189	728	2	.	.	PUNCT
admet-189	729	1	pharmacol	pharmacol	NOUN
admet-189	729	2	.	.	PROPN
admet-189	730	1	6	6	NUM
admet-189	730	2	(	(	PUNCT
admet-189	730	3	2006	2006	NUM
admet-189	730	4	)	)	PUNCT
admet-189	730	5	494	494	NUM
admet-189	730	6	-	-	SYM
admet-189	730	7	500	500	NUM
admet-189	730	8	.	.	PUNCT
admet-189	731	1	[	[	X
admet-189	731	2	76	76	NUM
admet-189	731	3	]	]	X
admet-189	731	4	l.	l.	PROPN
admet-189	731	5	costantino	costantino	PROPN
admet-189	731	6	,	,	PUNCT
admet-189	731	7	d.	d.	PROPN
admet-189	731	8	boraschi	boraschi	PROPN
admet-189	731	9	,	,	PUNCT
admet-189	731	10	drug	drug	NOUN
admet-189	731	11	discovery	discovery	NOUN
admet-189	731	12	today	today	NOUN
admet-189	731	13	17	17	NUM
admet-189	731	14	(	(	PUNCT
admet-189	731	15	2012	2012	NUM
admet-189	731	16	)	)	PUNCT
admet-189	731	17	367	367	NUM
admet-189	731	18	-	-	SYM
admet-189	731	19	378	378	NUM
admet-189	731	20	.	.	PUNCT
admet-189	732	1	[	[	X
admet-189	732	2	77	77	NUM
admet-189	732	3	]	]	X
admet-189	732	4	w.m	w.m	PROPN
admet-189	732	5	.	.	PROPN
admet-189	732	6	pardridge	pardridge	PROPN
admet-189	732	7	,	,	PUNCT
admet-189	732	8	j.	j.	PROPN
admet-189	732	9	cereb	cereb	PROPN
admet-189	732	10	.	.	PUNCT
admet-189	733	1	blood	blood	NOUN
admet-189	733	2	flow	flow	NOUN
admet-189	733	3	met	meet	VERB
admet-189	733	4	.	.	PUNCT
admet-189	734	1	17	17	NUM
admet-189	734	2	(	(	PUNCT
admet-189	734	3	1997	1997	NUM
admet-189	734	4	)	)	PUNCT
admet-189	734	5	713	713	NUM
admet-189	734	6	-	-	SYM
admet-189	734	7	731	731	NUM
admet-189	734	8	.	.	PUNCT
admet-189	735	1	[	[	X
admet-189	735	2	78	78	X
admet-189	735	3	]	]	X
admet-189	735	4	y.	y.	PROPN
admet-189	735	5	zhang	zhang	PROPN
admet-189	735	6	,	,	PUNCT
admet-189	735	7	f.	f.	PROPN
admet-189	735	8	calon	calon	PROPN
admet-189	735	9	,	,	PUNCT
admet-189	735	10	c.	c.	PROPN
admet-189	735	11	zhu	zhu	PROPN
admet-189	735	12	,	,	PUNCT
admet-189	735	13	r.j	r.j	PROPN
admet-189	735	14	.	.	PROPN
admet-189	735	15	boado	boado	PROPN
admet-189	735	16	,	,	PUNCT
admet-189	735	17	w.m	w.m	PROPN
admet-189	735	18	.	.	PROPN
admet-189	735	19	pardridge	pardridge	PROPN
admet-189	735	20	,	,	PUNCT
admet-189	735	21	hum	hum	ADJ
admet-189	735	22	.	.	PUNCT
admet-189	736	1	gene	gene	NOUN
admet-189	736	2	ther	ther	ADV
admet-189	736	3	.	.	PUNCT
admet-189	737	1	14	14	NUM
admet-189	737	2	(	(	PUNCT
admet-189	737	3	2003	2003	NUM
admet-189	737	4	)	)	PUNCT
admet-189	737	5	1	1	NUM
admet-189	737	6	-	-	SYM
admet-189	737	7	12	12	NUM
admet-189	737	8	.	.	PUNCT
admet-189	738	1	[	[	X
admet-189	738	2	79	79	NUM
admet-189	738	3	]	]	X
admet-189	738	4	r.t	r.t	PROPN
admet-189	738	5	.	.	PROPN
admet-189	738	6	carroll	carroll	PROPN
admet-189	738	7	,	,	PUNCT
admet-189	738	8	d.	d.	PROPN
admet-189	738	9	bhatia	bhatia	PROPN
admet-189	738	10	,	,	PUNCT
admet-189	738	11	w.	w.	PROPN
admet-189	738	12	geldenhuys	geldenhuys	PROPN
admet-189	738	13	,	,	PUNCT
admet-189	738	14	r.	r.	PROPN
admet-189	738	15	bhatia	bhatia	PROPN
admet-189	738	16	,	,	PUNCT
admet-189	738	17	n.	n.	PROPN
admet-189	738	18	miladore	miladore	ADV
admet-189	738	19	,	,	PUNCT
admet-189	738	20	a.	a.	NOUN
admet-189	738	21	bishayee	bishayee	PROPN
admet-189	738	22	,	,	PUNCT
admet-189	738	23	v.	v.	ADP
admet-189	738	24	sutariya	sutariya	PROPN
admet-189	738	25	,	,	PUNCT
admet-189	738	26	j.	j.	PROPN
admet-189	738	27	drug	drug	PROPN
admet-189	738	28	target	target	PROPN
admet-189	738	29	18	18	NUM
admet-189	738	30	(	(	PUNCT
admet-189	738	31	2010	2010	NUM
admet-189	738	32	)	)	PUNCT
admet-189	738	33	665	665	NUM
admet-189	738	34	-	-	SYM
admet-189	738	35	674	674	NUM
admet-189	738	36	.	.	PUNCT
admet-189	739	1	[	[	X
admet-189	739	2	80	80	NUM
admet-189	739	3	]	]	X
admet-189	739	4	y.a	y.a	PROPN
admet-189	739	5	.	.	PROPN
admet-189	739	6	suzuki	suzuki	PROPN
admet-189	739	7	,	,	PUNCT
admet-189	739	8	v.	v.	ADP
admet-189	739	9	lopez	lopez	PROPN
admet-189	739	10	,	,	PUNCT
admet-189	739	11	b.	b.	PROPN
admet-189	739	12	lonnerdal	lonnerdal	PROPN
admet-189	739	13	,	,	PUNCT
admet-189	739	14	cell	cell	NOUN
admet-189	739	15	mol	mol	PROPN
admet-189	739	16	.	.	PUNCT
admet-189	739	17	life	life	PROPN
admet-189	739	18	sci	sci	PROPN
admet-189	739	19	.	.	PROPN
admet-189	740	1	62	62	NUM
admet-189	740	2	(	(	PUNCT
admet-189	740	3	2005	2005	NUM
admet-189	740	4	)	)	PUNCT
admet-189	740	5	2560	2560	NUM
admet-189	740	6	-	-	SYM
admet-189	740	7	2575	2575	NUM
admet-189	740	8	.	.	PUNCT
admet-189	741	1	[	[	X
admet-189	741	2	81	81	NUM
admet-189	741	3	]	]	PUNCT
admet-189	741	4	b.	b.	PROPN
admet-189	741	5	ji	ji	PROPN
admet-189	741	6	,	,	PUNCT
admet-189	741	7	j.	j.	PROPN
admet-189	741	8	maeda	maeda	PROPN
admet-189	741	9	,	,	PUNCT
admet-189	741	10	m.	m.	PROPN
admet-189	741	11	higuchi	higuchi	PROPN
admet-189	741	12	,	,	PUNCT
admet-189	741	13	k.	k.	PROPN
admet-189	741	14	inoue	inoue	PROPN
admet-189	741	15	,	,	PUNCT
admet-189	741	16	h.	h.	PROPN
admet-189	741	17	akita	akita	PROPN
admet-189	741	18	,	,	PUNCT
admet-189	741	19	h.	h.	PROPN
admet-189	741	20	harashima	harashima	PROPN
admet-189	741	21	,	,	PUNCT
admet-189	741	22	t.	t.	NOUN
admet-189	741	23	suhara	suhara	NOUN
admet-189	741	24	,	,	PUNCT
admet-189	741	25	life	life	NOUN
admet-189	741	26	.	.	PUNCT
admet-189	742	1	sci	sci	PROPN
admet-189	742	2	.	.	PROPN
admet-189	742	3	78	78	NUM
admet-189	742	4	(	(	PUNCT
admet-189	742	5	2006	2006	NUM
admet-189	742	6	)	)	PUNCT
admet-189	742	7	851	851	NUM
admet-189	742	8	-	-	SYM
admet-189	742	9	855	855	NUM
admet-189	742	10	.	.	PUNCT
admet-189	743	1	[	[	X
admet-189	743	2	82	82	NUM
admet-189	743	3	]	]	PUNCT
admet-189	743	4	k.	k.	PROPN
admet-189	743	5	hu	hu	PROPN
admet-189	743	6	,	,	PUNCT
admet-189	743	7	y.	y.	PROPN
admet-189	743	8	shi	shi	PROPN
admet-189	743	9	,	,	PUNCT
admet-189	743	10	w.	w.	PROPN
admet-189	743	11	jiang	jiang	PROPN
admet-189	743	12	,	,	PUNCT
admet-189	743	13	j.	j.	PROPN
admet-189	743	14	han	han	PROPN
admet-189	743	15	,	,	PUNCT
admet-189	743	16	s.	s.	PROPN
admet-189	743	17	huang	huang	PROPN
admet-189	743	18	,	,	PUNCT
admet-189	743	19	x.	x.	PROPN
admet-189	743	20	jiang	jiang	PROPN
admet-189	743	21	,	,	PUNCT
admet-189	743	22	int	int	PROPN
admet-189	743	23	.	.	PUNCT
admet-189	744	1	j.	j.	PROPN
admet-189	744	2	pharm	pharm	PROPN
admet-189	744	3	.	.	PUNCT
admet-189	745	1	415	415	NUM
admet-189	745	2	(	(	PUNCT
admet-189	745	3	2011	2011	NUM
admet-189	745	4	)	)	PUNCT
admet-189	745	5	273	273	NUM
admet-189	745	6	-	-	SYM
admet-189	745	7	283	283	NUM
admet-189	745	8	.	.	PUNCT
admet-189	746	1	[	[	X
admet-189	746	2	83	83	NUM
admet-189	746	3	]	]	X
admet-189	746	4	r.	r.	PROPN
admet-189	746	5	huang	huang	PROPN
admet-189	746	6	,	,	PUNCT
admet-189	746	7	w.	w.	PROPN
admet-189	746	8	ke	ke	PROPN
admet-189	746	9	,	,	PUNCT
admet-189	746	10	y.	y.	PROPN
admet-189	746	11	liu	liu	PROPN
admet-189	746	12	,	,	PUNCT
admet-189	746	13	d.	d.	PROPN
admet-189	746	14	wu	wu	PROPN
admet-189	746	15	,	,	PUNCT
admet-189	746	16	l.	l.	PROPN
admet-189	746	17	feng	feng	PROPN
admet-189	746	18	,	,	PUNCT
admet-189	746	19	c.	c.	PROPN
admet-189	746	20	jiang	jiang	PROPN
admet-189	746	21	,	,	PUNCT
admet-189	746	22	y.	y.	PROPN
admet-189	746	23	pei	pei	PROPN
admet-189	746	24	,	,	PUNCT
admet-189	746	25	j.	j.	PROPN
admet-189	746	26	neurol	neurol	PROPN
admet-189	746	27	.	.	PUNCT
admet-189	747	1	sci	sci	PROPN
admet-189	747	2	.	.	PROPN
admet-189	748	1	290	290	NUM
admet-189	748	2	(	(	PUNCT
admet-189	748	3	2010	2010	NUM
admet-189	748	4	)	)	PUNCT
admet-189	748	5	123	123	NUM
admet-189	748	6	-	-	SYM
admet-189	748	7	130	130	NUM
admet-189	748	8	.	.	PUNCT
admet-189	749	1	[	[	X
admet-189	749	2	84	84	NUM
admet-189	749	3	]	]	X
admet-189	749	4	s.	s.	PROPN
admet-189	749	5	wagner	wagner	PROPN
admet-189	749	6	,	,	PUNCT
admet-189	749	7	a.	a.	NOUN
admet-189	749	8	zensi	zensi	PROPN
admet-189	749	9	,	,	PUNCT
admet-189	749	10	s.l	s.l	PROPN
admet-189	749	11	.	.	PROPN
admet-189	749	12	wien	wien	PROPN
admet-189	749	13	,	,	PUNCT
admet-189	749	14	s.e	s.e	PROPN
admet-189	749	15	.	.	PROPN
admet-189	749	16	tschickardt	tschickardt	PROPN
admet-189	749	17	,	,	PUNCT
admet-189	749	18	w.	w.	PROPN
admet-189	749	19	maier	maier	PROPN
admet-189	749	20	,	,	PUNCT
admet-189	749	21	t.	t.	PROPN
admet-189	749	22	vogel	vogel	PROPN
admet-189	749	23	,	,	PUNCT
admet-189	749	24	f.	f.	PROPN
admet-189	749	25	worek	worek	PROPN
admet-189	749	26	,	,	PUNCT
admet-189	749	27	c.u	c.u	PROPN
admet-189	749	28	.	.	PROPN
admet-189	749	29	pietrzik	pietrzik	PROPN
admet-189	749	30	,	,	PUNCT
admet-189	749	31	j.	j.	PROPN
admet-189	749	32	kreuter	kreuter	PROPN
admet-189	749	33	,	,	PUNCT
admet-189	749	34	h.	h.	PROPN
admet-189	749	35	von	von	PROPN
admet-189	749	36	briesen	briesen	PROPN
admet-189	749	37	,	,	PUNCT
admet-189	749	38	plos	plos	PROPN
admet-189	749	39	one	one	NUM
admet-189	749	40	7	7	NUM
admet-189	749	41	(	(	PUNCT
admet-189	749	42	2012	2012	NUM
admet-189	749	43	)	)	PUNCT
admet-189	749	44	e32568	e32568	PROPN
admet-189	749	45	.	.	PUNCT
admet-189	750	1	[	[	X
admet-189	750	2	85	85	NUM
admet-189	750	3	]	]	PUNCT
admet-189	750	4	s.	s.	PROPN
admet-189	750	5	pillay	pillay	PROPN
admet-189	750	6	,	,	PUNCT
admet-189	750	7	v.	v.	PROPN
admet-189	750	8	pillay	pillay	PROPN
admet-189	750	9	,	,	PUNCT
admet-189	750	10	y.e	y.e	PROPN
admet-189	750	11	.	.	PROPN
admet-189	750	12	choonara	choonara	PROPN
admet-189	750	13	,	,	PUNCT
admet-189	750	14	d.	d.	PROPN
admet-189	750	15	naidoo	naidoo	PROPN
admet-189	750	16	,	,	PUNCT
admet-189	750	17	r.a	r.a	PROPN
admet-189	750	18	.	.	PROPN
admet-189	750	19	khan	khan	PROPN
admet-189	750	20	,	,	PUNCT
admet-189	750	21	l.c	l.c	PROPN
admet-189	750	22	.	.	PROPN
admet-189	750	23	du	du	PROPN
admet-189	750	24	toit	toit	PROPN
admet-189	750	25	,	,	PUNCT
admet-189	750	26	v.m	v.m	PROPN
admet-189	750	27	.	.	PROPN
admet-189	750	28	ndesendo	ndesendo	PROPN
admet-189	750	29	,	,	PUNCT
admet-189	750	30	g.	g.	PROPN
admet-189	750	31	modi	modi	PROPN
admet-189	750	32	,	,	PUNCT
admet-189	750	33	m.p	m.p	PROPN
admet-189	750	34	.	.	PROPN
admet-189	750	35	danckwerts	danckwert	NOUN
admet-189	750	36	,	,	PUNCT
admet-189	750	37	s.e	s.e	PROPN
admet-189	750	38	.	.	PROPN
admet-189	750	39	iyuke	iyuke	PROPN
admet-189	750	40	,	,	PUNCT
admet-189	750	41	int	int	NOUN
admet-189	750	42	.	.	PUNCT
admet-189	751	1	j.	j.	PROPN
admet-189	751	2	pharm	pharm	PROPN
admet-189	751	3	.	.	PUNCT
admet-189	752	1	382	382	NUM
admet-189	752	2	(	(	PUNCT
admet-189	752	3	2009	2009	NUM
admet-189	752	4	)	)	PUNCT
admet-189	752	5	277	277	NUM
admet-189	752	6	-	-	SYM
admet-189	752	7	290	290	NUM
admet-189	752	8	.	.	PUNCT
admet-189	753	1	[	[	X
admet-189	753	2	86	86	NUM
admet-189	753	3	]	]	PUNCT
admet-189	753	4	s.	s.	PROPN
admet-189	753	5	woerly	woerly	PROPN
admet-189	753	6	,	,	PUNCT
admet-189	753	7	s.	s.	PROPN
admet-189	753	8	fort	fort	PROPN
admet-189	753	9	,	,	PUNCT
admet-189	753	10	i.	i.	PROPN
admet-189	753	11	pignot	pignot	PROPN
admet-189	753	12	-	-	PUNCT
admet-189	753	13	paintrand	paintrand	NOUN
admet-189	753	14	,	,	PUNCT
admet-189	753	15	c.	c.	PROPN
admet-189	753	16	cottet	cottet	PROPN
admet-189	753	17	,	,	PUNCT
admet-189	753	18	c.	c.	PROPN
admet-189	753	19	carcenac	carcenac	PROPN
admet-189	753	20	,	,	PUNCT
admet-189	753	21	m.	m.	NOUN
admet-189	753	22	savasta	savasta	NOUN
admet-189	753	23	,	,	PUNCT
admet-189	753	24	biomacromolecules	biomacromolecule	NOUN
admet-189	753	25	9	9	NUM
admet-189	753	26	(	(	PUNCT
admet-189	753	27	2008	2008	NUM
admet-189	753	28	)	)	PUNCT
admet-189	753	29	2329	2329	NUM
admet-189	753	30	-	-	SYM
admet-189	753	31	2337	2337	NUM
admet-189	753	32	.	.	PUNCT
admet-189	754	1	[	[	X
admet-189	754	2	87	87	NUM
admet-189	754	3	]	]	X
admet-189	754	4	j.g	j.g	PROPN
admet-189	754	5	.	.	PROPN
admet-189	754	6	nutt	nutt	PROPN
admet-189	754	7	,	,	PUNCT
admet-189	754	8	k.j	k.j	PROPN
admet-189	754	9	.	.	PROPN
admet-189	754	10	burchiel	burchiel	PROPN
admet-189	754	11	,	,	PUNCT
admet-189	754	12	c.l	c.l	PROPN
admet-189	754	13	.	.	PROPN
admet-189	754	14	comella	comella	PROPN
admet-189	754	15	,	,	PUNCT
admet-189	754	16	j.	j.	PROPN
admet-189	754	17	jankovic	jankovic	PROPN
admet-189	754	18	,	,	PUNCT
admet-189	754	19	a.e	a.e	PROPN
admet-189	754	20	.	.	PROPN
admet-189	754	21	lang	lang	PROPN
admet-189	754	22	,	,	PUNCT
admet-189	754	23	e.r	e.r	PROPN
admet-189	754	24	.	.	PROPN
admet-189	754	25	laws	law	NOUN
admet-189	754	26	,	,	PUNCT
admet-189	754	27	jr	jr	PROPN
admet-189	754	28	.	.	PROPN
admet-189	754	29	,	,	PUNCT
admet-189	754	30	a.m.	a.m.	PROPN
admet-189	754	31	lozano	lozano	PROPN
admet-189	754	32	,	,	PUNCT
admet-189	754	33	r.d	r.d	PROPN
admet-189	754	34	.	.	PROPN
admet-189	754	35	penn	penn	PROPN
admet-189	754	36	,	,	PUNCT
admet-189	754	37	r.k	r.k	PROPN
admet-189	754	38	.	.	PROPN
admet-189	754	39	simpson	simpson	PROPN
admet-189	754	40	,	,	PUNCT
admet-189	754	41	jr	jr	PROPN
admet-189	754	42	.	.	PROPN
admet-189	754	43	,	,	PUNCT
admet-189	754	44	m.	m.	PROPN
admet-189	754	45	stacy	stacy	PROPN
admet-189	754	46	,	,	PUNCT
admet-189	754	47	g.f	g.f	PROPN
admet-189	754	48	.	.	PROPN
admet-189	754	49	wooten	wooten	PROPN
admet-189	754	50	,	,	PUNCT
admet-189	754	51	neurology	neurology	NOUN
admet-189	754	52	60	60	NUM
admet-189	754	53	(	(	PUNCT
admet-189	754	54	2003	2003	NUM
admet-189	754	55	)	)	PUNCT
admet-189	754	56	69	69	NUM
admet-189	754	57	-	-	SYM
admet-189	754	58	73	73	NUM
admet-189	754	59	.	.	PUNCT
admet-189	755	1	[	[	X
admet-189	755	2	88	88	NUM
admet-189	755	3	]	]	X
admet-189	755	4	j.j	j.j	PROPN
admet-189	755	5	.	.	PROPN
admet-189	755	6	lochhead	lochhead	PROPN
admet-189	755	7	,	,	PUNCT
admet-189	755	8	r.g	r.g	PROPN
admet-189	755	9	.	.	PROPN
admet-189	755	10	thorne	thorne	PROPN
admet-189	755	11	,	,	PUNCT
admet-189	755	12	adv	adv	PROPN
admet-189	755	13	.	.	PUNCT
admet-189	755	14	drug	drug	PROPN
admet-189	755	15	deliv	deliv	PROPN
admet-189	755	16	.	.	PUNCT
admet-189	756	1	rev	rev	PROPN
admet-189	756	2	.	.	PROPN
admet-189	756	3	64	64	NUM
admet-189	756	4	(	(	PUNCT
admet-189	756	5	2012	2012	NUM
admet-189	756	6	)	)	PUNCT
admet-189	756	7	614	614	NUM
admet-189	756	8	-	-	SYM
admet-189	756	9	628	628	NUM
admet-189	756	10	.	.	PUNCT
admet-189	757	1	[	[	X
admet-189	757	2	89	89	NUM
admet-189	757	3	]	]	X
admet-189	757	4	h.l	h.l	PROPN
admet-189	757	5	.	.	PROPN
admet-189	757	6	wong	wong	PROPN
admet-189	757	7	,	,	PUNCT
admet-189	757	8	x.y	x.y	PROPN
admet-189	757	9	.	.	PROPN
admet-189	757	10	wu	wu	PROPN
admet-189	757	11	,	,	PUNCT
admet-189	757	12	r.	r.	PROPN
admet-189	757	13	bendayan	bendayan	PROPN
admet-189	757	14	,	,	PUNCT
admet-189	757	15	adv	adv	PROPN
admet-189	757	16	.	.	PUNCT
admet-189	757	17	drug	drug	PROPN
admet-189	757	18	deliv	deliv	PROPN
admet-189	757	19	.	.	PUNCT
admet-189	757	20	rev	rev	PROPN
admet-189	757	21	.	.	PROPN
admet-189	757	22	64	64	NUM
admet-189	757	23	(	(	PUNCT
admet-189	757	24	2012	2012	NUM
admet-189	757	25	)	)	PUNCT
admet-189	757	26	686	686	NUM
admet-189	757	27	-	-	SYM
admet-189	757	28	700	700	NUM
admet-189	757	29	.	.	PUNCT
admet-189	758	1	[	[	X
admet-189	758	2	90	90	NUM
admet-189	758	3	]	]	X
admet-189	758	4	t.k	t.k	PROPN
admet-189	758	5	.	.	PROPN
admet-189	758	6	vyas	vyas	PROPN
admet-189	758	7	,	,	PUNCT
admet-189	758	8	a.	a.	NOUN
admet-189	758	9	shahiwala	shahiwala	PROPN
admet-189	758	10	,	,	PUNCT
admet-189	758	11	s.	s.	PROPN
admet-189	758	12	marathe	marathe	PROPN
admet-189	758	13	,	,	PUNCT
admet-189	758	14	a.	a.	NOUN
admet-189	758	15	misra	misra	PROPN
admet-189	758	16	,	,	PUNCT
admet-189	758	17	curr	curr	PROPN
admet-189	758	18	.	.	PROPN
admet-189	758	19	drug	drug	PROPN
admet-189	758	20	deliv	deliv	NOUN
admet-189	758	21	.	.	PUNCT
admet-189	759	1	2	2	NUM
admet-189	759	2	(	(	PUNCT
admet-189	759	3	2005	2005	NUM
admet-189	759	4	)	)	PUNCT
admet-189	759	5	165	165	NUM
admet-189	759	6	-	-	SYM
admet-189	759	7	175	175	NUM
admet-189	759	8	.	.	PUNCT
admet-189	760	1	[	[	X
admet-189	760	2	91	91	NUM
admet-189	760	3	]	]	PUNCT
admet-189	760	4	z.	z.	PROPN
admet-189	760	5	wen	wen	PROPN
admet-189	760	6	,	,	PUNCT
admet-189	760	7	z.	z.	PROPN
admet-189	760	8	yan	yan	PROPN
admet-189	760	9	,	,	PUNCT
admet-189	760	10	k.	k.	PROPN
admet-189	760	11	hu	hu	PROPN
admet-189	760	12	,	,	PUNCT
admet-189	760	13	z.	z.	PROPN
admet-189	760	14	pang	pang	PROPN
admet-189	760	15	,	,	PUNCT
admet-189	760	16	x.	x.	PROPN
admet-189	760	17	cheng	cheng	PROPN
admet-189	760	18	,	,	PUNCT
admet-189	760	19	l.	l.	PROPN
admet-189	760	20	guo	guo	PROPN
admet-189	760	21	,	,	PUNCT
admet-189	760	22	q.	q.	PROPN
admet-189	760	23	zhang	zhang	PROPN
admet-189	760	24	,	,	PUNCT
admet-189	760	25	x.	x.	PROPN
admet-189	760	26	jiang	jiang	PROPN
admet-189	760	27	,	,	PUNCT
admet-189	760	28	l.	l.	PROPN
admet-189	760	29	fang	fang	PROPN
admet-189	760	30	,	,	PUNCT
admet-189	760	31	r.	r.	PROPN
admet-189	760	32	lai	lai	PROPN
admet-189	760	33	,	,	PUNCT
admet-189	760	34	j.	j.	PROPN
admet-189	760	35	control	control	PROPN
admet-189	760	36	.	.	PUNCT
admet-189	761	1	release	release	VERB
admet-189	761	2	151	151	NUM
admet-189	761	3	(	(	PUNCT
admet-189	761	4	2011	2011	NUM
admet-189	761	5	)	)	PUNCT
admet-189	761	6	131	131	NUM
admet-189	761	7	-	-	SYM
admet-189	761	8	138	138	NUM
admet-189	761	9	.	.	PUNCT
admet-189	762	1	[	[	X
admet-189	762	2	92	92	NUM
admet-189	762	3	]	]	X
admet-189	762	4	m.m	m.m	PROPN
admet-189	762	5	.	.	PROPN
admet-189	762	6	migliore	migliore	PROPN
admet-189	762	7	,	,	PUNCT
admet-189	762	8	r.	r.	PROPN
admet-189	762	9	ortiz	ortiz	PROPN
admet-189	762	10	,	,	PUNCT
admet-189	762	11	s.	s.	PROPN
admet-189	762	12	dye	dye	PROPN
admet-189	762	13	,	,	PUNCT
admet-189	762	14	r.b	r.b	PROPN
admet-189	762	15	.	.	PROPN
admet-189	762	16	campbell	campbell	PROPN
admet-189	762	17	,	,	PUNCT
admet-189	762	18	m.m	m.m	PROPN
admet-189	762	19	.	.	PROPN
admet-189	762	20	amiji	amiji	PROPN
admet-189	762	21	,	,	PUNCT
admet-189	762	22	b.l	b.l	PROPN
admet-189	762	23	.	.	PROPN
admet-189	762	24	waszczak	waszczak	PROPN
admet-189	762	25	,	,	PUNCT
admet-189	762	26	neuroscience	neuroscience	NOUN
admet-189	762	27	274	274	NUM
admet-189	762	28	(	(	PUNCT
admet-189	762	29	2014	2014	NUM
admet-189	762	30	)	)	PUNCT
admet-189	762	31	11	11	NUM
admet-189	762	32	-	-	SYM
admet-189	762	33	23	23	NUM
admet-189	762	34	.	.	PUNCT
admet-189	763	1	[	[	X
admet-189	763	2	93	93	X
admet-189	763	3	]	]	PUNCT
admet-189	763	4	s.	s.	PROPN
admet-189	763	5	sharma	sharma	PROPN
admet-189	763	6	,	,	PUNCT
admet-189	763	7	s.	s.	PROPN
admet-189	763	8	lohan	lohan	PROPN
admet-189	763	9	,	,	PUNCT
admet-189	763	10	r.s	r.s	PROPN
admet-189	763	11	.	.	PROPN
admet-189	763	12	murthy	murthy	PROPN
admet-189	763	13	,	,	PUNCT
admet-189	763	14	drug	drug	PROPN
admet-189	763	15	dev	dev	PROPN
admet-189	763	16	.	.	PUNCT
admet-189	764	1	ind	ind	PROPN
admet-189	764	2	.	.	PUNCT
admet-189	765	1	pharm	pharm	PROPN
admet-189	765	2	.	.	PUNCT
admet-189	766	1	40	40	NUM
admet-189	766	2	(	(	PUNCT
admet-189	766	3	2014	2014	NUM
admet-189	766	4	)	)	PUNCT
admet-189	766	5	869	869	NUM
admet-189	766	6	-	-	SYM
admet-189	766	7	878	878	NUM
admet-189	766	8	.	.	PUNCT
admet-189	767	1	[	[	X
admet-189	767	2	94	94	X
admet-189	767	3	]	]	X
admet-189	767	4	s.	s.	PROPN
admet-189	767	5	md	md	PROPN
admet-189	767	6	,	,	PUNCT
admet-189	767	7	r.a	r.a	PROPN
admet-189	767	8	.	.	PROPN
admet-189	767	9	khan	khan	PROPN
admet-189	767	10	,	,	PUNCT
admet-189	767	11	g.	g.	PROPN
admet-189	767	12	mustafa	mustafa	PROPN
admet-189	767	13	,	,	PUNCT
admet-189	767	14	k.	k.	PROPN
admet-189	767	15	chuttani	chuttani	PROPN
admet-189	767	16	,	,	PUNCT
admet-189	767	17	s.	s.	PROPN
admet-189	767	18	baboota	baboota	PROPN
admet-189	767	19	,	,	PUNCT
admet-189	767	20	j.k	j.k	PROPN
admet-189	767	21	.	.	PUNCT
admet-189	767	22	sahni	sahni	PROPN
admet-189	767	23	,	,	PUNCT
admet-189	767	24	j.	j.	PROPN
admet-189	767	25	ali	ali	PROPN
admet-189	767	26	,	,	PUNCT
admet-189	767	27	eur	eur	PROPN
admet-189	767	28	.	.	PUNCT
admet-189	768	1	j.	j.	PROPN
admet-189	768	2	pharm	pharm	PROPN
admet-189	768	3	.	.	PUNCT
admet-189	769	1	sci	sci	PROPN
admet-189	769	2	.	.	PROPN
admet-189	770	1	48	48	NUM
admet-189	770	2	(	(	PUNCT
admet-189	770	3	2013	2013	NUM
admet-189	770	4	)	)	PUNCT
admet-189	770	5	393	393	NUM
admet-189	770	6	-	-	SYM
admet-189	770	7	405	405	NUM
admet-189	770	8	.	.	PUNCT
admet-189	771	1	[	[	X
admet-189	771	2	95	95	NUM
admet-189	771	3	]	]	PUNCT
admet-189	771	4	r.	r.	PROPN
admet-189	771	5	banerjee	banerjee	PROPN
admet-189	771	6	,	,	PUNCT
admet-189	771	7	nanomedicine	nanomedicine	NOUN
admet-189	771	8	6	6	NUM
admet-189	771	9	(	(	PUNCT
admet-189	771	10	2011	2011	NUM
admet-189	771	11	)	)	PUNCT
admet-189	771	12	1657	1657	NUM
admet-189	771	13	-	-	SYM
admet-189	771	14	1660	1660	NUM
admet-189	771	15	.	.	PUNCT
admet-189	772	1	[	[	X
admet-189	772	2	96	96	NUM
admet-189	772	3	]	]	X
admet-189	772	4	i.	i.	PROPN
admet-189	772	5	kadiu	kadiu	PROPN
admet-189	772	6	,	,	PUNCT
admet-189	772	7	j.g	j.g	PROPN
admet-189	772	8	.	.	PROPN
admet-189	772	9	glanzer	glanzer	NOUN
admet-189	772	10	,	,	PUNCT
admet-189	772	11	j.	j.	PROPN
admet-189	772	12	kipnis	kipnis	PROPN
admet-189	772	13	,	,	PUNCT
admet-189	772	14	h.e	h.e	PROPN
admet-189	772	15	.	.	PROPN
admet-189	772	16	gendelman	gendelman	PROPN
admet-189	772	17	,	,	PUNCT
admet-189	772	18	m.p	m.p	PROPN
admet-189	772	19	.	.	PROPN
admet-189	772	20	thomas	thomas	PROPN
admet-189	772	21	,	,	PUNCT
admet-189	772	22	neurotox	neurotox	NOUN
admet-189	772	23	.	.	PUNCT
admet-189	773	1	res	re	NOUN
admet-189	773	2	.	.	PROPN
admet-189	773	3	8	8	NUM
admet-189	773	4	(	(	PUNCT
admet-189	773	5	2005	2005	NUM
admet-189	773	6	)	)	PUNCT
admet-189	773	7	25	25	NUM
admet-189	773	8	-	-	SYM
admet-189	773	9	50	50	NUM
admet-189	773	10	.	.	PUNCT
admet-189	774	1	[	[	X
admet-189	774	2	97	97	NUM
admet-189	774	3	]	]	X
admet-189	774	4	e.v	e.v	PROPN
admet-189	774	5	.	.	PROPN
admet-189	774	6	batrakova	batrakova	PROPN
admet-189	774	7	,	,	PUNCT
admet-189	774	8	s.	s.	PROPN
admet-189	774	9	li	li	PROPN
admet-189	774	10	,	,	PUNCT
admet-189	774	11	a.d	a.d	PROPN
admet-189	774	12	.	.	PROPN
admet-189	774	13	reynolds	reynolds	PROPN
admet-189	774	14	,	,	PUNCT
admet-189	774	15	r.l	r.l	PROPN
admet-189	774	16	.	.	PROPN
admet-189	774	17	mosley	mosley	PROPN
admet-189	774	18	,	,	PUNCT
admet-189	774	19	t.k	t.k	PROPN
admet-189	774	20	.	.	PROPN
admet-189	774	21	bronich	bronich	PROPN
admet-189	774	22	,	,	PUNCT
admet-189	774	23	a.v	a.v	PROPN
admet-189	774	24	.	.	PROPN
admet-189	774	25	kabanov	kabanov	PROPN
admet-189	774	26	,	,	PUNCT
admet-189	774	27	h.e	h.e	PROPN
admet-189	774	28	.	.	PROPN
admet-189	774	29	gendelman	gendelman	PROPN
admet-189	774	30	,	,	PUNCT
admet-189	774	31	bioconjug	bioconjug	NOUN
admet-189	774	32	.	.	PUNCT
admet-189	775	1	chem	chem	NOUN
admet-189	775	2	.	.	PUNCT
admet-189	776	1	18	18	NUM
admet-189	776	2	(	(	PUNCT
admet-189	776	3	2007	2007	NUM
admet-189	776	4	)	)	PUNCT
admet-189	776	5	1498	1498	NUM
admet-189	776	6	-	-	SYM
admet-189	776	7	1506	1506	NUM
admet-189	776	8	.	.	PUNCT
admet-189	777	1	[	[	X
admet-189	777	2	98	98	NUM
admet-189	777	3	]	]	X
admet-189	777	4	o.c	o.c	PROPN
admet-189	777	5	.	.	PROPN
admet-189	777	6	farokhzad	farokhzad	PROPN
admet-189	777	7	,	,	PUNCT
admet-189	777	8	r.	r.	PROPN
admet-189	777	9	langer	langer	PROPN
admet-189	777	10	,	,	PUNCT
admet-189	777	11	adv	adv	PROPN
admet-189	777	12	.	.	PUNCT
admet-189	777	13	drug	drug	PROPN
admet-189	777	14	deliv	deliv	PROPN
admet-189	777	15	.	.	PUNCT
admet-189	778	1	rev	rev	PROPN
admet-189	778	2	.	.	PROPN
admet-189	778	3	58	58	NUM
admet-189	778	4	(	(	PUNCT
admet-189	778	5	2006	2006	NUM
admet-189	778	6	)	)	PUNCT
admet-189	778	7	1456	1456	NUM
admet-189	778	8	-	-	SYM
admet-189	778	9	1459	1459	NUM
admet-189	778	10	.	.	PUNCT
admet-189	779	1	[	[	X
admet-189	779	2	99	99	NUM
admet-189	779	3	]	]	X
admet-189	779	4	r.	r.	PROPN
admet-189	779	5	qiao	qiao	PROPN
admet-189	779	6	,	,	PUNCT
admet-189	779	7	q.	q.	PROPN
admet-189	779	8	jia	jia	PROPN
admet-189	779	9	,	,	PUNCT
admet-189	779	10	s.	s.	PROPN
admet-189	779	11	huwel	huwel	PROPN
admet-189	779	12	,	,	PUNCT
admet-189	779	13	r.	r.	PROPN
admet-189	779	14	xia	xia	PROPN
admet-189	779	15	,	,	PUNCT
admet-189	779	16	t.	t.	PROPN
admet-189	779	17	liu	liu	PROPN
admet-189	779	18	,	,	PUNCT
admet-189	779	19	f.	f.	PROPN
admet-189	779	20	gao	gao	PROPN
admet-189	779	21	,	,	PUNCT
admet-189	779	22	h.j	h.j	PROPN
admet-189	779	23	.	.	PROPN
admet-189	779	24	galla	galla	PROPN
admet-189	779	25	,	,	PUNCT
admet-189	779	26	m.	m.	PROPN
admet-189	779	27	gao	gao	PROPN
admet-189	779	28	,	,	PUNCT
admet-189	779	29	acs	acs	PROPN
admet-189	779	30	nano	nano	VERB
admet-189	779	31	6	6	NUM
admet-189	779	32	(	(	PUNCT
admet-189	779	33	2012	2012	NUM
admet-189	779	34	)	)	PUNCT
admet-189	779	35	3304	3304	NUM
admet-189	779	36	-	-	SYM
admet-189	779	37	3310	3310	NUM
admet-189	779	38	.	.	PUNCT
admet-189	780	1	[	[	X
admet-189	780	2	100	100	NUM
admet-189	780	3	]	]	X
admet-189	780	4	t.l	t.l	X
admet-189	780	5	.	.	PUNCT
admet-189	780	6	hwang	hwang	PROPN
admet-189	780	7	,	,	PUNCT
admet-189	780	8	y.k	y.k	PROPN
admet-189	780	9	.	.	PROPN
admet-189	780	10	lin	lin	PROPN
admet-189	780	11	,	,	PUNCT
admet-189	780	12	c.h	c.h	PROPN
admet-189	780	13	.	.	PROPN
admet-189	780	14	chi	chi	PROPN
admet-189	780	15	,	,	PUNCT
admet-189	780	16	t.h	t.h	PROPN
admet-189	780	17	.	.	PROPN
admet-189	780	18	huang	huang	PROPN
admet-189	780	19	,	,	PUNCT
admet-189	780	20	j.y	j.y	PROPN
admet-189	780	21	.	.	PROPN
admet-189	780	22	fang	fang	PROPN
admet-189	780	23	,	,	PUNCT
admet-189	780	24	j.	j.	PROPN
admet-189	780	25	pharm	pharm	PROPN
admet-189	780	26	.	.	PUNCT
admet-189	781	1	sci	sci	PROPN
admet-189	781	2	.	.	PROPN
admet-189	782	1	98	98	NUM
admet-189	782	2	(	(	PUNCT
admet-189	782	3	2009	2009	NUM
admet-189	782	4	)	)	PUNCT
admet-189	782	5	3735	3735	NUM
admet-189	782	6	-	-	SYM
admet-189	782	7	3747	3747	NUM
admet-189	782	8	.	.	PUNCT
admet-189	783	1	[	[	X
admet-189	783	2	101	101	NUM
admet-189	783	3	]	]	PUNCT
admet-189	783	4	m.	m.	NOUN
admet-189	783	5	srikanth	srikanth	PROPN
admet-189	783	6	,	,	PUNCT
admet-189	783	7	j.a	j.a	PROPN
admet-189	783	8	.	.	PROPN
admet-189	783	9	kessler	kessler	PROPN
admet-189	783	10	,	,	PUNCT
admet-189	783	11	nat	nat	PROPN
admet-189	783	12	.	.	PUNCT
admet-189	784	1	rev	rev	PROPN
admet-189	784	2	.	.	PROPN
admet-189	784	3	neur	neur	PROPN
admet-189	784	4	.	.	PROPN
admet-189	784	5	8	8	NUM
admet-189	784	6	(	(	PUNCT
admet-189	784	7	2012	2012	NUM
admet-189	784	8	)	)	PUNCT
admet-189	784	9	307	307	NUM
admet-189	784	10	-	-	SYM
admet-189	784	11	318	318	NUM
admet-189	784	12	.	.	PUNCT
admet-189	785	1	r.	r.	PROPN
admet-189	785	2	banerjee	banerjee	PROPN
admet-189	785	3	et	et	PROPN
admet-189	785	4	al	al	PROPN
admet-189	785	5	.	.	PROPN
admet-189	785	6	admet	admet	PROPN
admet-189	785	7	&	&	CCONJ
admet-189	785	8	dmpk	dmpk	PROPN
admet-189	785	9	3(3	3(3	NUM
admet-189	785	10	)	)	PUNCT
admet-189	785	11	(	(	PUNCT
admet-189	785	12	2015	2015	NUM
admet-189	785	13	)	)	PUNCT
admet-189	785	14	155	155	NUM
admet-189	785	15	-	-	SYM
admet-189	785	16	181	181	NUM
admet-189	785	17	180	180	NUM
admet-189	786	1	[	[	NOUN
admet-189	786	2	102	102	NUM
admet-189	786	3	]	]	PUNCT
admet-189	786	4	a.	a.	NOUN
admet-189	786	5	pinna	pinna	NOUN
admet-189	786	6	,	,	PUNCT
admet-189	786	7	l.	l.	PROPN
admet-189	786	8	malfatti	malfatti	PROPN
admet-189	786	9	,	,	PUNCT
admet-189	786	10	g.	g.	PROPN
admet-189	786	11	galleri	galleri	PROPN
admet-189	786	12	,	,	PUNCT
admet-189	786	13	r.	r.	PROPN
admet-189	786	14	manetti	manetti	PROPN
admet-189	786	15	,	,	PUNCT
admet-189	786	16	s.	s.	PROPN
admet-189	786	17	cossu	cossu	PROPN
admet-189	786	18	,	,	PUNCT
admet-189	786	19	g.	g.	PROPN
admet-189	786	20	rocchitta	rocchitta	PROPN
admet-189	786	21	,	,	PUNCT
admet-189	786	22	r.	r.	PROPN
admet-189	786	23	migheli	migheli	PROPN
admet-189	786	24	,	,	PUNCT
admet-189	786	25	p.a	p.a	PROPN
admet-189	786	26	.	.	PROPN
admet-189	786	27	serra	serra	PROPN
admet-189	786	28	,	,	PUNCT
admet-189	786	29	p.	p.	NOUN
admet-189	786	30	innocenzi	innocenzi	PROPN
admet-189	786	31	,	,	PUNCT
admet-189	786	32	rsc	rsc	PROPN
admet-189	786	33	advances	advance	VERB
admet-189	786	34	5	5	NUM
admet-189	786	35	(	(	PUNCT
admet-189	786	36	2015	2015	NUM
admet-189	786	37	)	)	PUNCT
admet-189	786	38	20432	20432	NUM
admet-189	786	39	-	-	SYM
admet-189	786	40	20439	20439	NUM
admet-189	786	41	.	.	PUNCT
admet-189	787	1	[	[	X
admet-189	787	2	103	103	NUM
admet-189	787	3	]	]	X
admet-189	787	4	c.	c.	PROPN
admet-189	787	5	wiener	wiener	NOUN
admet-189	787	6	,	,	PUNCT
admet-189	787	7	a.	a.	NOUN
admet-189	787	8	fauci	fauci	PROPN
admet-189	787	9	,	,	PUNCT
admet-189	787	10	e.	e.	PROPN
admet-189	787	11	braunwald	braunwald	PROPN
admet-189	787	12	,	,	PUNCT
admet-189	787	13	d.	d.	PROPN
admet-189	787	14	kasper	kasper	PROPN
admet-189	787	15	,	,	PUNCT
admet-189	787	16	s.	s.	PROPN
admet-189	787	17	hauser	hauser	PROPN
admet-189	787	18	,	,	PUNCT
admet-189	787	19	d.	d.	PROPN
admet-189	787	20	longo	longo	PROPN
admet-189	787	21	,	,	PUNCT
admet-189	787	22	j.	j.	PROPN
admet-189	787	23	jameson	jameson	PROPN
admet-189	787	24	,	,	PUNCT
admet-189	787	25	j.	j.	PROPN
admet-189	787	26	loscalzo	loscalzo	PROPN
admet-189	787	27	,	,	PUNCT
admet-189	787	28	harrison	harrison	PROPN
admet-189	787	29	's	's	PART
admet-189	787	30	principles	principle	NOUN
admet-189	787	31	of	of	ADP
admet-189	787	32	internal	internal	ADJ
admet-189	787	33	medicine	medicine	NOUN
admet-189	787	34	,	,	PUNCT
admet-189	787	35	self	self	NOUN
admet-189	787	36	-	-	PUNCT
admet-189	787	37	assessment	assessment	NOUN
admet-189	787	38	and	and	CCONJ
admet-189	787	39	board	board	PROPN
admet-189	787	40	review	review	PROPN
admet-189	787	41	,	,	PUNCT
admet-189	787	42	mcgraw	mcgraw	PROPN
admet-189	787	43	-	-	PUNCT
admet-189	787	44	hill	hill	NOUN
admet-189	787	45	education	education	NOUN
admet-189	787	46	,	,	PUNCT
admet-189	787	47	2008	2008	NUM
admet-189	787	48	.	.	PUNCT
admet-189	788	1	[	[	X
admet-189	788	2	104	104	X
admet-189	788	3	]	]	PUNCT
admet-189	788	4	r.	r.	PROPN
admet-189	788	5	huang	huang	PROPN
admet-189	788	6	,	,	PUNCT
admet-189	788	7	w.	w.	PROPN
admet-189	788	8	ke	ke	PROPN
admet-189	788	9	,	,	PUNCT
admet-189	788	10	y.	y.	PROPN
admet-189	788	11	liu	liu	PROPN
admet-189	788	12	,	,	PUNCT
admet-189	788	13	d.	d.	PROPN
admet-189	788	14	wu	wu	PROPN
admet-189	788	15	,	,	PUNCT
admet-189	788	16	l.	l.	PROPN
admet-189	788	17	feng	feng	PROPN
admet-189	788	18	,	,	PUNCT
admet-189	788	19	c.	c.	PROPN
admet-189	788	20	jiang	jiang	PROPN
admet-189	788	21	,	,	PUNCT
admet-189	788	22	y.	y.	PROPN
admet-189	788	23	pei	pei	PROPN
admet-189	788	24	,	,	PUNCT
admet-189	788	25	j.	j.	PROPN
admet-189	788	26	neur	neur	PROPN
admet-189	788	27	.	.	PUNCT
admet-189	789	1	sci	sci	PROPN
admet-189	789	2	.	.	PROPN
admet-189	790	1	290	290	NUM
admet-189	790	2	(	(	PUNCT
admet-189	790	3	2010	2010	NUM
admet-189	790	4	)	)	PUNCT
admet-189	790	5	123	123	NUM
admet-189	790	6	-	-	SYM
admet-189	790	7	130	130	NUM
admet-189	790	8	.	.	PUNCT
admet-189	791	1	[	[	X
admet-189	791	2	105	105	NUM
admet-189	791	3	]	]	X
admet-189	791	4	r.	r.	PROPN
admet-189	791	5	huang	huang	PROPN
admet-189	791	6	,	,	PUNCT
admet-189	791	7	h.	h.	PROPN
admet-189	791	8	ma	ma	PROPN
admet-189	791	9	,	,	PUNCT
admet-189	791	10	y.	y.	PROPN
admet-189	791	11	guo	guo	PROPN
admet-189	791	12	,	,	PUNCT
admet-189	791	13	s.	s.	PROPN
admet-189	791	14	liu	liu	PROPN
admet-189	791	15	,	,	PUNCT
admet-189	791	16	y.	y.	PROPN
admet-189	791	17	kuang	kuang	PROPN
admet-189	791	18	,	,	PUNCT
admet-189	791	19	k.	k.	PROPN
admet-189	791	20	shao	shao	PROPN
admet-189	791	21	,	,	PUNCT
admet-189	791	22	j.	j.	PROPN
admet-189	791	23	li	li	PROPN
admet-189	791	24	,	,	PUNCT
admet-189	791	25	y.	y.	PROPN
admet-189	791	26	liu	liu	PROPN
admet-189	791	27	,	,	PUNCT
admet-189	791	28	l.	l.	PROPN
admet-189	791	29	han	han	PROPN
admet-189	791	30	,	,	PUNCT
admet-189	791	31	s.	s.	PROPN
admet-189	791	32	huang	huang	PROPN
admet-189	791	33	,	,	PUNCT
admet-189	791	34	s.	s.	PROPN
admet-189	791	35	an	an	PROPN
admet-189	791	36	,	,	PUNCT
admet-189	791	37	l.	l.	PROPN
admet-189	791	38	ye	ye	PROPN
admet-189	791	39	,	,	PUNCT
admet-189	791	40	j.	j.	PROPN
admet-189	791	41	lou	lou	PROPN
admet-189	791	42	,	,	PUNCT
admet-189	791	43	c.	c.	PROPN
admet-189	791	44	jiang	jiang	PROPN
admet-189	791	45	,	,	PUNCT
admet-189	791	46	pharm	pharm	PROPN
admet-189	791	47	.	.	PUNCT
admet-189	792	1	res	re	NOUN
admet-189	792	2	.	.	PROPN
admet-189	793	1	30	30	NUM
admet-189	793	2	(	(	PUNCT
admet-189	793	3	2013	2013	NUM
admet-189	793	4	)	)	PUNCT
admet-189	793	5	2549	2549	NUM
admet-189	793	6	-	-	SYM
admet-189	793	7	2559	2559	NUM
admet-189	793	8	.	.	PUNCT
admet-189	794	1	[	[	X
admet-189	794	2	106	106	X
admet-189	794	3	]	]	PUNCT
admet-189	794	4	x.	x.	PROPN
admet-189	794	5	cai	cai	PROPN
admet-189	794	6	,	,	PUNCT
admet-189	794	7	h.	h.	PROPN
admet-189	794	8	jia	jia	PROPN
admet-189	794	9	,	,	PUNCT
admet-189	794	10	z.	z.	PROPN
admet-189	794	11	liu	liu	PROPN
admet-189	794	12	,	,	PUNCT
admet-189	794	13	b.	b.	PROPN
admet-189	794	14	hou	hou	PROPN
admet-189	794	15	,	,	PUNCT
admet-189	794	16	c.	c.	PROPN
admet-189	794	17	luo	luo	PROPN
admet-189	794	18	,	,	PUNCT
admet-189	794	19	z.	z.	PROPN
admet-189	794	20	feng	feng	PROPN
admet-189	794	21	,	,	PUNCT
admet-189	794	22	w.	w.	PROPN
admet-189	794	23	li	li	PROPN
admet-189	794	24	,	,	PUNCT
admet-189	794	25	j.	j.	PROPN
admet-189	794	26	liu	liu	PROPN
admet-189	794	27	,	,	PUNCT
admet-189	794	28	j.	j.	PROPN
admet-189	794	29	neurosci	neurosci	PROPN
admet-189	794	30	.	.	PUNCT
admet-189	795	1	res	re	NOUN
admet-189	795	2	.	.	PUNCT
admet-189	796	1	86	86	NUM
admet-189	796	2	(	(	PUNCT
admet-189	796	3	2008	2008	NUM
admet-189	796	4	)	)	PUNCT
admet-189	796	5	3622	3622	NUM
admet-189	796	6	-	-	SYM
admet-189	796	7	3634	3634	NUM
admet-189	796	8	.	.	PUNCT
admet-189	797	1	[	[	X
admet-189	797	2	107	107	NUM
admet-189	797	3	]	]	X
admet-189	797	4	l.l	l.l	PROPN
admet-189	797	5	.	.	PROPN
admet-189	797	6	dugan	dugan	PROPN
admet-189	797	7	,	,	PUNCT
admet-189	797	8	l.	l.	PROPN
admet-189	797	9	tian	tian	PROPN
admet-189	797	10	,	,	PUNCT
admet-189	797	11	k.l	k.l	PROPN
admet-189	797	12	.	.	PROPN
admet-189	797	13	quick	quick	PROPN
admet-189	797	14	,	,	PUNCT
admet-189	797	15	j.i	j.i	PROPN
admet-189	797	16	.	.	PUNCT
admet-189	797	17	hardt	hardt	PROPN
admet-189	797	18	,	,	PUNCT
admet-189	797	19	m.	m.	PROPN
admet-189	797	20	karimi	karimi	PROPN
admet-189	797	21	,	,	PUNCT
admet-189	797	22	c.	c.	PROPN
admet-189	797	23	brown	brown	PROPN
admet-189	797	24	,	,	PUNCT
admet-189	797	25	s.	s.	PROPN
admet-189	797	26	loftin	loftin	PROPN
admet-189	797	27	,	,	PUNCT
admet-189	797	28	h.	h.	PROPN
admet-189	797	29	flores	flores	PROPN
admet-189	797	30	,	,	PUNCT
admet-189	797	31	s.m	s.m	PROPN
admet-189	797	32	.	.	PROPN
admet-189	797	33	moerlein	moerlein	PROPN
admet-189	797	34	,	,	PUNCT
admet-189	797	35	j.	j.	PROPN
admet-189	797	36	polich	polich	PROPN
admet-189	797	37	,	,	PUNCT
admet-189	797	38	s.d	s.d	PROPN
admet-189	797	39	.	.	PROPN
admet-189	797	40	tabbal	tabbal	PROPN
admet-189	797	41	,	,	PUNCT
admet-189	797	42	j.w	j.w	PROPN
admet-189	797	43	.	.	PROPN
admet-189	797	44	mink	mink	PROPN
admet-189	797	45	,	,	PUNCT
admet-189	797	46	j.s	j.s	PROPN
admet-189	797	47	.	.	PROPN
admet-189	797	48	perlmutter	perlmutter	PROPN
admet-189	797	49	,	,	PUNCT
admet-189	797	50	ann	ann	PROPN
admet-189	797	51	.	.	PUNCT
admet-189	798	1	neurol	neurol	PROPN
admet-189	798	2	.	.	PUNCT
admet-189	799	1	76	76	NUM
admet-189	800	1	(	(	PUNCT
admet-189	800	2	2014	2014	NUM
admet-189	800	3	)	)	PUNCT
admet-189	800	4	393	393	NUM
admet-189	800	5	-	-	SYM
admet-189	800	6	402	402	NUM
admet-189	800	7	.	.	PUNCT
admet-189	801	1	[	[	X
admet-189	801	2	108	108	NUM
admet-189	801	3	]	]	PUNCT
admet-189	801	4	z.	z.	PROPN
admet-189	801	5	zhou	zhou	PROPN
admet-189	801	6	,	,	PUNCT
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admet-189	801	8	5	5	NUM
admet-189	801	9	(	(	PUNCT
admet-189	801	10	2013	2013	NUM
admet-189	801	11	)	)	PUNCT
admet-189	801	12	525	525	NUM
admet-189	801	13	-	-	SYM
admet-189	801	14	541	541	NUM
admet-189	801	15	.	.	PUNCT
admet-189	802	1	[	[	X
admet-189	802	2	109	109	NUM
admet-189	802	3	]	]	PUNCT
admet-189	802	4	g.	g.	PROPN
admet-189	802	5	deuschl	deuschl	PROPN
admet-189	802	6	,	,	PUNCT
admet-189	802	7	c.	c.	PROPN
admet-189	802	8	schade	schade	PROPN
admet-189	802	9	-	-	PUNCT
admet-189	802	10	brittinger	brittinger	NOUN
admet-189	802	11	,	,	PUNCT
admet-189	802	12	p.	p.	NOUN
admet-189	802	13	krack	krack	NOUN
admet-189	802	14	,	,	PUNCT
admet-189	802	15	j.	j.	PROPN
admet-189	802	16	volkmann	volkmann	PROPN
admet-189	802	17	,	,	PUNCT
admet-189	802	18	h.	h.	PROPN
admet-189	802	19	schäfer	schäfer	PROPN
admet-189	802	20	,	,	PUNCT
admet-189	802	21	k.	k.	PROPN
admet-189	802	22	bötzel	bötzel	PROPN
admet-189	802	23	,	,	PUNCT
admet-189	802	24	c.	c.	PROPN
admet-189	802	25	daniels	daniels	PROPN
admet-189	802	26	,	,	PUNCT
admet-189	802	27	a.	a.	NOUN
admet-189	802	28	deutschländer	deutschländer	PROPN
admet-189	802	29	,	,	PUNCT
admet-189	802	30	u.	u.	PROPN
admet-189	802	31	dillmann	dillmann	PROPN
admet-189	802	32	,	,	PUNCT
admet-189	802	33	w.	w.	PROPN
admet-189	802	34	eisner	eisner	PROPN
admet-189	802	35	,	,	PUNCT
admet-189	802	36	d.	d.	PROPN
admet-189	802	37	gruber	gruber	PROPN
admet-189	802	38	,	,	PUNCT
admet-189	802	39	w.	w.	PROPN
admet-189	802	40	hamel	hamel	PROPN
admet-189	802	41	,	,	PUNCT
admet-189	802	42	j.	j.	PROPN
admet-189	802	43	herzog	herzog	PROPN
admet-189	802	44	,	,	PUNCT
admet-189	802	45	r.	r.	PROPN
admet-189	802	46	hilker	hilker	PROPN
admet-189	802	47	,	,	PUNCT
admet-189	802	48	s.	s.	PROPN
admet-189	802	49	klebe	klebe	PROPN
admet-189	802	50	,	,	PUNCT
admet-189	802	51	m.	m.	NOUN
admet-189	802	52	kloß	kloß	PROPN
admet-189	802	53	,	,	PUNCT
admet-189	802	54	j.	j.	PROPN
admet-189	802	55	koy	koy	PROPN
admet-189	802	56	,	,	PUNCT
admet-189	802	57	m.	m.	NOUN
admet-189	802	58	krause	krause	PROPN
admet-189	802	59	,	,	PUNCT
admet-189	802	60	a.	a.	PROPN
admet-189	802	61	kupsch	kupsch	PROPN
admet-189	802	62	,	,	PUNCT
admet-189	802	63	d.	d.	PROPN
admet-189	802	64	lorenz	lorenz	PROPN
admet-189	802	65	,	,	PUNCT
admet-189	802	66	s.	s.	PROPN
admet-189	802	67	lorenzl	lorenzl	PROPN
admet-189	802	68	,	,	PUNCT
admet-189	802	69	h.m	h.m	PROPN
admet-189	802	70	.	.	PROPN
admet-189	802	71	mehdorn	mehdorn	PROPN
admet-189	802	72	,	,	PUNCT
admet-189	802	73	j.r	j.r	PROPN
admet-189	802	74	.	.	PROPN
admet-189	802	75	moringlane	moringlane	PROPN
admet-189	802	76	,	,	PUNCT
admet-189	802	77	w.	w.	PROPN
admet-189	802	78	oertel	oertel	PROPN
admet-189	802	79	,	,	PUNCT
admet-189	802	80	m.o	m.o	PROPN
admet-189	802	81	.	.	PROPN
admet-189	802	82	pinsker	pinsker	PROPN
admet-189	802	83	,	,	PUNCT
admet-189	802	84	h.	h.	PROPN
admet-189	802	85	reichmann	reichmann	PROPN
admet-189	802	86	,	,	PUNCT
admet-189	802	87	a.	a.	NOUN
admet-189	802	88	reuß	reuß	NOUN
admet-189	802	89	,	,	PUNCT
admet-189	802	90	g.h	g.h	PROPN
admet-189	802	91	.	.	PROPN
admet-189	802	92	schneider	schneider	PROPN
admet-189	802	93	,	,	PUNCT
admet-189	802	94	a.	a.	NOUN
admet-189	802	95	schnitzler	schnitzler	PROPN
admet-189	802	96	,	,	PUNCT
admet-189	802	97	u.	u.	PROPN
admet-189	802	98	steude	steude	PROPN
admet-189	802	99	,	,	PUNCT
admet-189	802	100	v.	v.	PROPN
admet-189	802	101	sturm	sturm	PROPN
admet-189	802	102	,	,	PUNCT
admet-189	802	103	l.	l.	PROPN
admet-189	802	104	timmermann	timmermann	PROPN
admet-189	802	105	,	,	PUNCT
admet-189	802	106	v.	v.	ADP
admet-189	802	107	tronnier	tronnier	NOUN
admet-189	802	108	,	,	PUNCT
admet-189	802	109	t.	t.	PROPN
admet-189	802	110	trottenberg	trottenberg	PROPN
admet-189	802	111	,	,	PUNCT
admet-189	802	112	l.	l.	PROPN
admet-189	802	113	wojtecki	wojtecki	PROPN
admet-189	802	114	,	,	PUNCT
admet-189	802	115	e.	e.	PROPN
admet-189	802	116	wolf	wolf	PROPN
admet-189	802	117	,	,	PUNCT
admet-189	802	118	w.	w.	PROPN
admet-189	802	119	poewe	poewe	PROPN
admet-189	802	120	,	,	PUNCT
admet-189	802	121	j.	j.	PROPN
admet-189	802	122	voges	voges	PROPN
admet-189	802	123	,	,	PUNCT
admet-189	802	124	n.	n.	PROPN
admet-189	802	125	eng	eng	PROPN
admet-189	802	126	.	.	PUNCT
admet-189	802	127	j.	j.	PROPN
admet-189	802	128	med	med	PROPN
admet-189	802	129	.	.	PROPN
admet-189	803	1	355	355	NUM
admet-189	803	2	(	(	PUNCT
admet-189	803	3	2006	2006	NUM
admet-189	803	4	)	)	PUNCT
admet-189	803	5	896	896	NUM
admet-189	803	6	-	-	SYM
admet-189	803	7	908	908	NUM
admet-189	803	8	.	.	PUNCT
admet-189	804	1	[	[	X
admet-189	804	2	110	110	NUM
admet-189	804	3	]	]	X
admet-189	804	4	f.m	f.m	PROPN
admet-189	804	5	.	.	PROPN
admet-189	804	6	weaver	weaver	PROPN
admet-189	804	7	,	,	PUNCT
admet-189	804	8	k.	k.	PROPN
admet-189	804	9	follett	follett	PROPN
admet-189	804	10	,	,	PUNCT
admet-189	804	11	m.	m.	NOUN
admet-189	804	12	stern	stern	PROPN
admet-189	804	13	,	,	PUNCT
admet-189	804	14	k.	k.	PROPN
admet-189	804	15	hur	hur	PROPN
admet-189	804	16	,	,	PUNCT
admet-189	804	17	c.	c.	PROPN
admet-189	804	18	harris	harris	PROPN
admet-189	804	19	,	,	PUNCT
admet-189	804	20	w.j	w.j	PROPN
admet-189	804	21	.	.	PROPN
admet-189	804	22	marks	marks	PROPN
admet-189	804	23	jr	jr	PROPN
admet-189	804	24	,	,	PUNCT
admet-189	804	25	j.	j.	PROPN
admet-189	804	26	rothlind	rothlind	PROPN
admet-189	804	27	,	,	PUNCT
admet-189	804	28	o.	o.	PROPN
admet-189	804	29	sagher	sagher	PROPN
admet-189	804	30	,	,	PUNCT
admet-189	804	31	d.	d.	PROPN
admet-189	804	32	reda	reda	PROPN
admet-189	804	33	,	,	PUNCT
admet-189	804	34	c.s	c.s	PROPN
admet-189	804	35	.	.	PROPN
admet-189	804	36	moy	moy	PROPN
admet-189	804	37	,	,	PUNCT
admet-189	804	38	r.	r.	PROPN
admet-189	804	39	pahwa	pahwa	PROPN
admet-189	804	40	,	,	PUNCT
admet-189	804	41	k.	k.	PROPN
admet-189	804	42	burchiel	burchiel	PROPN
admet-189	804	43	,	,	PUNCT
admet-189	804	44	p.	p.	NOUN
admet-189	804	45	hogarth	hogarth	NOUN
admet-189	804	46	,	,	PUNCT
admet-189	804	47	e.c	e.c	PROPN
admet-189	804	48	.	.	PROPN
admet-189	804	49	lai	lai	PROPN
admet-189	804	50	,	,	PUNCT
admet-189	804	51	j.e	j.e	PROPN
admet-189	804	52	.	.	PROPN
admet-189	804	53	duda	duda	PROPN
admet-189	804	54	,	,	PUNCT
admet-189	804	55	k.	k.	PROPN
admet-189	804	56	holloway	holloway	PROPN
admet-189	804	57	,	,	PUNCT
admet-189	804	58	a.	a.	NOUN
admet-189	804	59	samii	samii	PROPN
admet-189	804	60	,	,	PUNCT
admet-189	804	61	s.	s.	PROPN
admet-189	804	62	horn	horn	PROPN
admet-189	804	63	,	,	PUNCT
admet-189	804	64	j.	j.	PROPN
admet-189	804	65	bronstein	bronstein	PROPN
admet-189	804	66	,	,	PUNCT
admet-189	804	67	g.	g.	PROPN
admet-189	804	68	stoner	stoner	PROPN
admet-189	804	69	,	,	PUNCT
admet-189	804	70	j.	j.	PROPN
admet-189	804	71	heemskerk	heemskerk	PROPN
admet-189	804	72	,	,	PUNCT
admet-189	804	73	g.d	g.d	PROPN
admet-189	804	74	.	.	PROPN
admet-189	804	75	huang	huang	PROPN
admet-189	804	76	,	,	PUNCT
admet-189	804	77	jama	jama	PROPN
admet-189	804	78	j.	j.	PROPN
admet-189	804	79	301	301	NUM
admet-189	804	80	(	(	PUNCT
admet-189	804	81	2009	2009	NUM
admet-189	804	82	)	)	PUNCT
admet-189	804	83	63	63	NUM
admet-189	804	84	-	-	SYM
admet-189	804	85	73	73	NUM
admet-189	804	86	.	.	PUNCT
admet-189	805	1	[	[	X
admet-189	805	2	111	111	NUM
admet-189	805	3	]	]	PUNCT
admet-189	805	4	m.	m.	NOUN
admet-189	805	5	christen	christen	PROPN
admet-189	805	6	,	,	PUNCT
admet-189	805	7	m.	m.	NOUN
admet-189	805	8	bittlinger	bittlinger	NOUN
admet-189	805	9	,	,	PUNCT
admet-189	805	10	h.	h.	PROPN
admet-189	805	11	walter	walter	PROPN
admet-189	805	12	,	,	PUNCT
admet-189	805	13	p.	p.	PROPN
admet-189	805	14	brugger	brugger	PROPN
admet-189	805	15	,	,	PUNCT
admet-189	805	16	s.	s.	PROPN
admet-189	805	17	müller	müller	PROPN
admet-189	805	18	,	,	PUNCT
admet-189	805	19	ajob	ajob	VERB
admet-189	805	20	neuroscience	neuroscience	NOUN
admet-189	805	21	3	3	NUM
admet-189	805	22	(	(	PUNCT
admet-189	805	23	2012	2012	NUM
admet-189	805	24	)	)	PUNCT
admet-189	805	25	37	37	NUM
admet-189	805	26	-	-	SYM
admet-189	805	27	43	43	NUM
admet-189	805	28	.	.	PUNCT
admet-189	806	1	[	[	X
admet-189	806	2	112	112	NUM
admet-189	806	3	]	]	PUNCT
admet-189	806	4	k.	k.	PROPN
admet-189	806	5	wang	wang	PROPN
admet-189	806	6	,	,	PUNCT
admet-189	806	7	h.a	h.a	PROPN
admet-189	806	8	.	.	PROPN
admet-189	806	9	fishman	fishman	PROPN
admet-189	806	10	,	,	PUNCT
admet-189	806	11	h.	h.	PROPN
admet-189	806	12	dai	dai	PROPN
admet-189	806	13	,	,	PUNCT
admet-189	806	14	j.s	j.s	PROPN
admet-189	806	15	.	.	PROPN
admet-189	806	16	harris	harris	PROPN
admet-189	806	17	,	,	PUNCT
admet-189	806	18	nano	nano	PROPN
admet-189	806	19	lett	lett	PROPN
admet-189	806	20	.	.	PROPN
admet-189	806	21	6	6	NUM
admet-189	806	22	(	(	PUNCT
admet-189	806	23	2006	2006	NUM
admet-189	806	24	)	)	PUNCT
admet-189	806	25	2043	2043	NUM
admet-189	806	26	-	-	SYM
admet-189	806	27	2048	2048	NUM
admet-189	806	28	.	.	PUNCT
admet-189	807	1	[	[	X
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admet-189	807	3	]	]	SYM
admet-189	807	4	d.b	d.b	PROPN
admet-189	807	5	.	.	PROPN
admet-189	807	6	mccreery	mccreery	PROPN
admet-189	807	7	,	,	PUNCT
admet-189	807	8	w.f	w.f	PROPN
admet-189	807	9	.	.	PROPN
admet-189	807	10	agnew	agnew	PROPN
admet-189	807	11	,	,	PUNCT
admet-189	807	12	t.g	t.g	PROPN
admet-189	807	13	.	.	PROPN
admet-189	807	14	yuen	yuen	PROPN
admet-189	807	15	,	,	PUNCT
admet-189	807	16	l.a	l.a	PROPN
admet-189	807	17	.	.	PROPN
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admet-189	807	19	,	,	PUNCT
admet-189	807	20	ann	ann	PROPN
admet-189	807	21	.	.	PROPN
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admet-189	807	23	.	.	PUNCT
admet-189	808	1	eng	eng	PROPN
admet-189	808	2	.	.	PROPN
admet-189	809	1	16	16	NUM
admet-189	809	2	(	(	PUNCT
admet-189	809	3	1988	1988	NUM
admet-189	809	4	)	)	PUNCT
admet-189	809	5	463	463	NUM
admet-189	809	6	-	-	SYM
admet-189	809	7	481	481	NUM
admet-189	809	8	.	.	PUNCT
admet-189	810	1	[	[	X
admet-189	810	2	114	114	NUM
admet-189	810	3	]	]	X
admet-189	810	4	d.r	d.r	PROPN
admet-189	810	5	.	.	PROPN
admet-189	810	6	merrill	merrill	PROPN
admet-189	810	7	,	,	PUNCT
admet-189	810	8	m.	m.	NOUN
admet-189	810	9	bikson	bikson	PROPN
admet-189	810	10	,	,	PUNCT
admet-189	810	11	j.g.r	j.g.r	PROPN
admet-189	810	12	.	.	PROPN
admet-189	810	13	jefferys	jefferys	PROPN
admet-189	810	14	,	,	PUNCT
admet-189	810	15	j.	j.	PROPN
admet-189	810	16	neurosci	neurosci	PROPN
admet-189	810	17	.	.	PROPN
admet-189	810	18	met	meet	VERB
admet-189	810	19	.	.	PUNCT
admet-189	811	1	141	141	NUM
admet-189	811	2	(	(	PUNCT
admet-189	811	3	2005	2005	NUM
admet-189	811	4	)	)	PUNCT
admet-189	811	5	171	171	NUM
admet-189	811	6	-	-	SYM
admet-189	811	7	198	198	NUM
admet-189	811	8	.	.	PUNCT
admet-189	812	1	[	[	X
admet-189	812	2	115	115	NUM
admet-189	812	3	]	]	X
admet-189	812	4	u.a	u.a	PROPN
admet-189	812	5	.	.	PROPN
admet-189	812	6	aregueta	aregueta	PROPN
admet-189	812	7	-	-	PUNCT
admet-189	812	8	robles	robles	PROPN
admet-189	812	9	,	,	PUNCT
admet-189	812	10	a.j	a.j	PROPN
admet-189	812	11	.	.	PROPN
admet-189	812	12	woolley	woolley	PROPN
admet-189	812	13	,	,	PUNCT
admet-189	812	14	l.a	l.a	PROPN
admet-189	812	15	.	.	PROPN
admet-189	812	16	poole	poole	PROPN
admet-189	812	17	-	-	PUNCT
admet-189	812	18	warren	warren	PROPN
admet-189	812	19	,	,	PUNCT
admet-189	812	20	n.h	n.h	PROPN
admet-189	812	21	.	.	PUNCT
admet-189	812	22	lovell	lovell	PROPN
admet-189	812	23	,	,	PUNCT
admet-189	812	24	r.a	r.a	PROPN
admet-189	812	25	.	.	PROPN
admet-189	812	26	green	green	PROPN
admet-189	812	27	,	,	PUNCT
admet-189	812	28	front	front	NOUN
admet-189	812	29	.	.	PUNCT
admet-189	813	1	neuroeng	neuroeng	PROPN
admet-189	813	2	.	.	PROPN
admet-189	814	1	7	7	NUM
admet-189	814	2	(	(	PUNCT
admet-189	814	3	2014	2014	NUM
admet-189	814	4	)	)	PUNCT
admet-189	814	5	15	15	NUM
admet-189	814	6	.	.	PUNCT
admet-189	815	1	[	[	X
admet-189	815	2	116	116	X
admet-189	815	3	]	]	X
admet-189	815	4	p.m.	p.m.	NOUN
admet-189	815	5	george	george	PROPN
admet-189	815	6	,	,	PUNCT
admet-189	815	7	a.w	a.w	PROPN
admet-189	815	8	.	.	PROPN
admet-189	815	9	lyckman	lyckman	PROPN
admet-189	815	10	,	,	PUNCT
admet-189	815	11	d.a	d.a	PROPN
admet-189	815	12	.	.	PROPN
admet-189	815	13	lavan	lavan	PROPN
admet-189	815	14	,	,	PUNCT
admet-189	815	15	a.	a.	NOUN
admet-189	815	16	hegde	hegde	PROPN
admet-189	815	17	,	,	PUNCT
admet-189	815	18	y.	y.	PROPN
admet-189	815	19	leung	leung	PROPN
admet-189	815	20	,	,	PUNCT
admet-189	815	21	r.	r.	PROPN
admet-189	815	22	avasare	avasare	PROPN
admet-189	815	23	,	,	PUNCT
admet-189	815	24	c.	c.	PROPN
admet-189	815	25	testa	testa	PROPN
admet-189	815	26	,	,	PUNCT
admet-189	815	27	p.m.	p.m.	NOUN
admet-189	815	28	alexander	alexander	PROPN
admet-189	815	29	,	,	PUNCT
admet-189	815	30	r.	r.	PROPN
admet-189	815	31	langer	langer	PROPN
admet-189	815	32	,	,	PUNCT
admet-189	815	33	m.	m.	NOUN
admet-189	815	34	sur	sur	PROPN
admet-189	815	35	,	,	PUNCT
admet-189	815	36	biomaterials	biomaterial	VERB
admet-189	815	37	26	26	NUM
admet-189	815	38	(	(	PUNCT
admet-189	815	39	2005	2005	NUM
admet-189	815	40	)	)	PUNCT
admet-189	815	41	3511	3511	NUM
admet-189	815	42	-	-	SYM
admet-189	815	43	3519	3519	NUM
admet-189	815	44	.	.	PUNCT
admet-189	816	1	[	[	X
admet-189	816	2	117	117	NUM
admet-189	816	3	]	]	X
admet-189	816	4	r.	r.	PROPN
admet-189	816	5	wadhwa	wadhwa	PROPN
admet-189	816	6	,	,	PUNCT
admet-189	816	7	c.f	c.f	PROPN
admet-189	816	8	.	.	PROPN
admet-189	816	9	lagenaur	lagenaur	PROPN
admet-189	816	10	,	,	PUNCT
admet-189	816	11	x.t	x.t	PROPN
admet-189	816	12	.	.	PROPN
admet-189	816	13	cui	cui	PROPN
admet-189	816	14	,	,	PUNCT
admet-189	816	15	j.	j.	PROPN
admet-189	816	16	control	control	PROPN
admet-189	816	17	.	.	PUNCT
admet-189	817	1	release	release	VERB
admet-189	817	2	110	110	NUM
admet-189	817	3	(	(	PUNCT
admet-189	817	4	2006	2006	NUM
admet-189	817	5	)	)	PUNCT
admet-189	817	6	531	531	NUM
admet-189	817	7	-	-	SYM
admet-189	817	8	541	541	NUM
admet-189	817	9	.	.	PUNCT
admet-189	818	1	[	[	X
admet-189	818	2	118	118	NUM
admet-189	818	3	]	]	X
admet-189	818	4	y.	y.	PROPN
admet-189	818	5	zhao	zhao	PROPN
admet-189	818	6	,	,	PUNCT
admet-189	818	7	b.	b.	PROPN
admet-189	818	8	liu	liu	PROPN
admet-189	818	9	,	,	PUNCT
admet-189	818	10	l.	l.	PROPN
admet-189	818	11	pan	pan	PROPN
admet-189	818	12	,	,	PUNCT
admet-189	818	13	g.	g.	PROPN
admet-189	818	14	yu	yu	PROPN
admet-189	818	15	,	,	PUNCT
admet-189	818	16	energ	energ	PROPN
admet-189	818	17	.	.	PUNCT
admet-189	819	1	environ	environ	PROPN
admet-189	819	2	.	.	PUNCT
admet-189	820	1	sci	sci	PROPN
admet-189	820	2	.	.	PROPN
admet-189	820	3	6	6	NUM
admet-189	820	4	(	(	PUNCT
admet-189	820	5	2013	2013	NUM
admet-189	820	6	)	)	PUNCT
admet-189	820	7	2856	2856	NUM
admet-189	820	8	-	-	SYM
admet-189	820	9	2870	2870	NUM
admet-189	820	10	.	.	PUNCT
admet-189	821	1	[	[	X
admet-189	821	2	119	119	NUM
admet-189	821	3	]	]	X
admet-189	821	4	j.k	j.k	PROPN
admet-189	821	5	.	.	PROPN
admet-189	821	6	nguyen	nguyen	PROPN
admet-189	821	7	,	,	PUNCT
admet-189	821	8	d.j	d.j	PROPN
admet-189	821	9	.	.	PROPN
admet-189	821	10	park	park	PROPN
admet-189	821	11	,	,	PUNCT
admet-189	821	12	j.l	j.l	PROPN
admet-189	821	13	.	.	PROPN
admet-189	821	14	skousen	skousen	PROPN
admet-189	821	15	,	,	PUNCT
admet-189	821	16	a.e	a.e	PROPN
admet-189	821	17	.	.	PROPN
admet-189	821	18	hess	hess	NOUN
admet-189	821	19	-	-	PUNCT
admet-189	821	20	dunning	dun	VERB
admet-189	821	21	,	,	PUNCT
admet-189	821	22	d.j	d.j	PROPN
admet-189	821	23	.	.	PROPN
admet-189	821	24	tyler	tyler	PROPN
admet-189	821	25	,	,	PUNCT
admet-189	821	26	s.j	s.j	PROPN
admet-189	821	27	.	.	PROPN
admet-189	821	28	rowan	rowan	PROPN
admet-189	821	29	,	,	PUNCT
admet-189	821	30	c.	c.	PROPN
admet-189	821	31	weder	weder	PROPN
admet-189	821	32	,	,	PUNCT
admet-189	821	33	j.r	j.r	PROPN
admet-189	821	34	.	.	PROPN
admet-189	821	35	capadona	capadona	PROPN
admet-189	821	36	,	,	PUNCT
admet-189	821	37	j.	j.	PROPN
admet-189	821	38	neural	neural	PROPN
admet-189	821	39	.	.	PUNCT
admet-189	822	1	eng	eng	PROPN
admet-189	822	2	.	.	PROPN
admet-189	822	3	11	11	NUM
admet-189	822	4	(	(	PUNCT
admet-189	822	5	2014	2014	NUM
admet-189	822	6	)	)	PUNCT
admet-189	822	7	056014	056014	NUM
admet-189	822	8	.	.	PUNCT
admet-189	823	1	[	[	X
admet-189	823	2	120	120	NUM
admet-189	823	3	]	]	X
admet-189	823	4	d.h	d.h	PROPN
admet-189	823	5	.	.	PROPN
admet-189	823	6	kim	kim	PROPN
admet-189	823	7	,	,	PUNCT
admet-189	823	8	m.	m.	NOUN
admet-189	823	9	abidian	abidian	PROPN
admet-189	823	10	,	,	PUNCT
admet-189	823	11	d.c	d.c	PROPN
admet-189	823	12	.	.	PUNCT
admet-189	823	13	martin	martin	PROPN
admet-189	823	14	,	,	PUNCT
admet-189	823	15	j.	j.	PROPN
admet-189	823	16	biomed	biome	VERB
admet-189	823	17	.	.	PUNCT
admet-189	824	1	mater	mater	NOUN
admet-189	824	2	.	.	PUNCT
admet-189	825	1	res	re	NOUN
admet-189	825	2	.	.	PUNCT
admet-189	826	1	a	a	DET
admet-189	826	2	71	71	NUM
admet-189	826	3	(	(	PUNCT
admet-189	826	4	2004	2004	NUM
admet-189	826	5	)	)	PUNCT
admet-189	826	6	577	577	NUM
admet-189	826	7	-	-	SYM
admet-189	826	8	585	585	NUM
admet-189	826	9	.	.	PUNCT
admet-189	827	1	[	[	X
admet-189	827	2	121	121	NUM
admet-189	827	3	]	]	PUNCT
admet-189	827	4	s.	s.	PROPN
admet-189	827	5	de	de	PROPN
admet-189	827	6	faveri	faveri	PROPN
admet-189	827	7	,	,	PUNCT
admet-189	827	8	e.	e.	PROPN
admet-189	827	9	maggiolini	maggiolini	PROPN
admet-189	827	10	,	,	PUNCT
admet-189	827	11	e.	e.	PROPN
admet-189	827	12	miele	miele	PROPN
admet-189	827	13	,	,	PUNCT
admet-189	827	14	f.	f.	PROPN
admet-189	827	15	de	de	PROPN
admet-189	827	16	angelis	angelis	PROPN
admet-189	827	17	,	,	PUNCT
admet-189	827	18	f.	f.	PROPN
admet-189	827	19	cesca	cesca	PROPN
admet-189	827	20	,	,	PUNCT
admet-189	827	21	f.	f.	PROPN
admet-189	827	22	benfenati	benfenati	PROPN
admet-189	827	23	,	,	PUNCT
admet-189	827	24	l.	l.	PROPN
admet-189	827	25	fadiga	fadiga	ADJ
admet-189	827	26	,	,	PUNCT
admet-189	827	27	front	front	NOUN
admet-189	827	28	.	.	PUNCT
admet-189	828	1	neuroeng	neuroeng	PROPN
admet-189	828	2	.	.	PROPN
admet-189	829	1	7	7	NUM
admet-189	829	2	(	(	PUNCT
admet-189	829	3	2014	2014	NUM
admet-189	829	4	)	)	PUNCT
admet-189	829	5	7	7	NUM
admet-189	829	6	.	.	PUNCT
admet-189	830	1	[	[	X
admet-189	830	2	122	122	NUM
admet-189	830	3	]	]	X
admet-189	830	4	m.f	m.f	PROPN
admet-189	830	5	.	.	PROPN
admet-189	830	6	yanik	yanik	PROPN
admet-189	830	7	,	,	PUNCT
admet-189	830	8	h.	h.	PROPN
admet-189	830	9	cinar	cinar	PROPN
admet-189	830	10	,	,	PUNCT
admet-189	830	11	h.n	h.n	PROPN
admet-189	830	12	.	.	PROPN
admet-189	830	13	cinar	cinar	PROPN
admet-189	830	14	,	,	PUNCT
admet-189	830	15	a.d	a.d	PROPN
admet-189	830	16	.	.	PROPN
admet-189	830	17	chisholm	chisholm	PROPN
admet-189	830	18	,	,	PUNCT
admet-189	830	19	y.	y.	PROPN
admet-189	830	20	jin	jin	PROPN
admet-189	830	21	,	,	PUNCT
admet-189	830	22	a.	a.	PROPN
admet-189	830	23	ben	ben	PROPN
admet-189	830	24	-	-	PUNCT
admet-189	830	25	yakar	yakar	PRON
admet-189	830	26	,	,	PUNCT
admet-189	830	27	nature	nature	NOUN
admet-189	830	28	432	432	NUM
admet-189	830	29	(	(	PUNCT
admet-189	830	30	2004	2004	NUM
admet-189	830	31	)	)	PUNCT
admet-189	830	32	822	822	NUM
admet-189	830	33	-	-	SYM
admet-189	830	34	822	822	NUM
admet-189	830	35	.	.	PUNCT
admet-189	831	1	[	[	X
admet-189	831	2	123	123	NUM
admet-189	831	3	]	]	PUNCT
admet-189	831	4	t.	t.	PROPN
admet-189	831	5	wu	wu	PROPN
admet-189	831	6	,	,	PUNCT
admet-189	831	7	s.	s.	PROPN
admet-189	831	8	mohanty	mohanty	PROPN
admet-189	831	9	,	,	PUNCT
admet-189	831	10	v.	v.	ADP
admet-189	831	11	gomez	gomez	PROPN
admet-189	831	12	-	-	PUNCT
admet-189	831	13	godinez	godinez	PROPN
admet-189	831	14	,	,	PUNCT
admet-189	831	15	l.z	l.z	PROPN
admet-189	831	16	.	.	PROPN
admet-189	831	17	shi	shi	PROPN
admet-189	831	18	,	,	PUNCT
admet-189	831	19	l.-h	l.-h	PROPN
admet-189	831	20	.	.	PUNCT
admet-189	832	1	liaw	liaw	PROPN
admet-189	832	2	,	,	PUNCT
admet-189	832	3	j.	j.	PROPN
admet-189	832	4	miotke	miotke	PROPN
admet-189	832	5	,	,	PUNCT
admet-189	832	6	r.l	r.l	PROPN
admet-189	832	7	.	.	PROPN
admet-189	832	8	meyer	meyer	PROPN
admet-189	832	9	,	,	PUNCT
admet-189	832	10	m.w	m.w	PROPN
admet-189	832	11	.	.	PROPN
admet-189	832	12	berns	berns	PROPN
admet-189	832	13	,	,	PUNCT
admet-189	832	14	j.	j.	PROPN
admet-189	832	15	roy	roy	PROPN
admet-189	832	16	.	.	PROPN
admet-189	832	17	soc	soc	PROPN
admet-189	832	18	.	.	PUNCT
admet-189	833	1	interface	interface	NOUN
admet-189	833	2	9	9	NUM
admet-189	833	3	(	(	PUNCT
admet-189	833	4	2012	2012	NUM
admet-189	833	5	)	)	PUNCT
admet-189	833	6	535	535	NUM
admet-189	833	7	-	-	SYM
admet-189	833	8	547	547	NUM
admet-189	833	9	.	.	PUNCT
admet-189	834	1	[	[	X
admet-189	834	2	124	124	NUM
admet-189	834	3	]	]	X
admet-189	834	4	e.d	e.d	PROPN
admet-189	834	5	.	.	PROPN
admet-189	834	6	kirson	kirson	PROPN
admet-189	834	7	,	,	PUNCT
admet-189	834	8	y.	y.	PROPN
admet-189	834	9	yaari	yaari	PROPN
admet-189	834	10	,	,	PUNCT
admet-189	834	11	j.	j.	PROPN
admet-189	834	12	neurosci	neurosci	PROPN
admet-189	834	13	.	.	PROPN
admet-189	834	14	met	meet	VERB
admet-189	834	15	98	98	NUM
admet-189	834	16	(	(	PUNCT
admet-189	834	17	2000	2000	NUM
admet-189	834	18	)	)	PUNCT
admet-189	834	19	119	119	NUM
admet-189	834	20	-	-	SYM
admet-189	834	21	122	122	NUM
admet-189	834	22	.	.	PUNCT
admet-189	835	1	[	[	X
admet-189	835	2	125	125	NUM
admet-189	835	3	]	]	PUNCT
admet-189	835	4	p.	p.	NOUN
admet-189	835	5	gorostiza	gorostiza	NOUN
admet-189	835	6	,	,	PUNCT
admet-189	835	7	e.	e.	PROPN
admet-189	835	8	isacoff	isacoff	PROPN
admet-189	835	9	,	,	PUNCT
admet-189	835	10	mol	mol	ADP
admet-189	835	11	biosys	biosys	NOUN
admet-189	835	12	.	.	PUNCT
admet-189	836	1	3	3	NUM
admet-189	836	2	(	(	PUNCT
admet-189	836	3	2007	2007	NUM
admet-189	836	4	)	)	PUNCT
admet-189	836	5	686	686	NUM
admet-189	836	6	-	-	SYM
admet-189	836	7	704	704	NUM
admet-189	836	8	.	.	PUNCT
admet-189	837	1	[	[	X
admet-189	837	2	126	126	NUM
admet-189	837	3	]	]	PUNCT
admet-189	837	4	v.	v.	CCONJ
admet-189	837	5	gradinaru	gradinaru	NOUN
admet-189	837	6	,	,	PUNCT
admet-189	837	7	m.	m.	NOUN
admet-189	837	8	mogri	mogri	PROPN
admet-189	837	9	,	,	PUNCT
admet-189	837	10	k.r	k.r	PROPN
admet-189	837	11	.	.	PROPN
admet-189	837	12	thompson	thompson	PROPN
admet-189	837	13	,	,	PUNCT
admet-189	837	14	j.m	j.m	PROPN
admet-189	837	15	.	.	PROPN
admet-189	837	16	henderson	henderson	PROPN
admet-189	837	17	,	,	PUNCT
admet-189	837	18	k.	k.	PROPN
admet-189	837	19	deisseroth	deisseroth	PROPN
admet-189	837	20	,	,	PUNCT
admet-189	837	21	science	science	NOUN
admet-189	837	22	324	324	NUM
admet-189	837	23	(	(	PUNCT
admet-189	837	24	2009	2009	NUM
admet-189	837	25	)	)	PUNCT
admet-189	837	26	354359	354359	NUM
admet-189	837	27	.	.	PUNCT
admet-189	838	1	[	[	X
admet-189	838	2	127	127	NUM
admet-189	838	3	]	]	X
admet-189	838	4	p.c	p.c	PROPN
admet-189	838	5	.	.	PROPN
admet-189	838	6	buttery	buttery	PROPN
admet-189	838	7	,	,	PUNCT
admet-189	838	8	r.a	r.a	PROPN
admet-189	838	9	.	.	PROPN
admet-189	838	10	barker	barker	PROPN
admet-189	838	11	,	,	PUNCT
admet-189	838	12	j.	j.	PROPN
admet-189	838	13	comp	comp	PROPN
admet-189	838	14	.	.	PUNCT
admet-189	839	1	neur	neur	PROPN
admet-189	839	2	.	.	PUNCT
admet-189	840	1	522	522	NUM
admet-189	840	2	(	(	PUNCT
admet-189	840	3	2014	2014	NUM
admet-189	840	4	)	)	PUNCT
admet-189	840	5	2802	2802	NUM
admet-189	840	6	-	-	SYM
admet-189	840	7	2816	2816	NUM
admet-189	840	8	.	.	PUNCT
admet-189	841	1	[	[	X
admet-189	841	2	128	128	NUM
admet-189	841	3	]	]	X
admet-189	841	4	r.a	r.a	PROPN
admet-189	841	5	.	.	PROPN
admet-189	841	6	barker	barker	PROPN
admet-189	841	7	,	,	PUNCT
admet-189	841	8	j.	j.	PROPN
admet-189	841	9	barrett	barrett	PROPN
admet-189	841	10	,	,	PUNCT
admet-189	841	11	s.l	s.l	PROPN
admet-189	841	12	.	.	PROPN
admet-189	841	13	mason	mason	PROPN
admet-189	841	14	,	,	PUNCT
admet-189	841	15	a.	a.	PROPN
admet-189	841	16	björklund	björklund	PROPN
admet-189	841	17	,	,	PUNCT
admet-189	841	18	lancet	lancet	PROPN
admet-189	841	19	neur	neur	PROPN
admet-189	841	20	.	.	PROPN
admet-189	842	1	12	12	NUM
admet-189	842	2	(	(	PUNCT
admet-189	842	3	2013	2013	NUM
admet-189	842	4	)	)	PUNCT
admet-189	842	5	84	84	NUM
admet-189	842	6	-	-	SYM
admet-189	842	7	91	91	NUM
admet-189	842	8	.	.	PUNCT
admet-189	843	1	[	[	X
admet-189	843	2	129	129	NUM
admet-189	843	3	]	]	X
admet-189	843	4	c.w	c.w	PROPN
admet-189	843	5	.	.	PROPN
admet-189	843	6	olanow	olanow	PROPN
admet-189	843	7	,	,	PUNCT
admet-189	843	8	c.g	c.g	PROPN
admet-189	843	9	.	.	PROPN
admet-189	843	10	goetz	goetz	PROPN
admet-189	843	11	,	,	PUNCT
admet-189	843	12	j.h	j.h	PROPN
admet-189	843	13	.	.	PROPN
admet-189	843	14	kordower	kordower	PROPN
admet-189	843	15	,	,	PUNCT
admet-189	843	16	a.j	a.j	PROPN
admet-189	843	17	.	.	PROPN
admet-189	843	18	stoessl	stoessl	PROPN
admet-189	843	19	,	,	PUNCT
admet-189	843	20	v.	v.	PROPN
admet-189	843	21	sossi	sossi	ADJ
admet-189	843	22	,	,	PUNCT
admet-189	843	23	m.f	m.f	PROPN
admet-189	843	24	.	.	PROPN
admet-189	843	25	brin	brin	PROPN
admet-189	843	26	,	,	PUNCT
admet-189	843	27	k.m	k.m	PROPN
admet-189	843	28	.	.	PROPN
admet-189	843	29	shannon	shannon	PROPN
admet-189	843	30	,	,	PUNCT
admet-189	843	31	g.m	g.m	PROPN
admet-189	843	32	.	.	PROPN
admet-189	843	33	nauert	nauert	PROPN
admet-189	843	34	,	,	PUNCT
admet-189	843	35	d.p	d.p	PROPN
admet-189	843	36	.	.	PROPN
admet-189	843	37	perl	perl	PROPN
admet-189	843	38	,	,	PUNCT
admet-189	843	39	j.	j.	PROPN
admet-189	843	40	godbold	godbold	PROPN
admet-189	843	41	,	,	PUNCT
admet-189	843	42	t.b	t.b	PROPN
admet-189	843	43	.	.	PROPN
admet-189	843	44	freeman	freeman	PROPN
admet-189	843	45	,	,	PUNCT
admet-189	843	46	ann	ann	PROPN
admet-189	843	47	.	.	PUNCT
admet-189	844	1	neurol	neurol	PROPN
admet-189	844	2	.	.	PUNCT
admet-189	845	1	54	54	NUM
admet-189	845	2	(	(	PUNCT
admet-189	845	3	2003	2003	NUM
admet-189	845	4	)	)	PUNCT
admet-189	845	5	403	403	NUM
admet-189	845	6	-	-	SYM
admet-189	845	7	414	414	NUM
admet-189	845	8	.	.	PUNCT
admet-189	846	1	admet	admet	PROPN
admet-189	846	2	&	&	CCONJ
admet-189	846	3	dmpk	dmpk	PROPN
admet-189	846	4	3(3	3(3	NUM
admet-189	846	5	)	)	PUNCT
admet-189	846	6	(	(	PUNCT
admet-189	846	7	2015	2015	NUM
admet-189	846	8	)	)	PUNCT
admet-189	846	9	155	155	NUM
admet-189	846	10	-	-	SYM
admet-189	846	11	181	181	NUM
admet-189	846	12	nanotechnology	nanotechnology	NOUN
admet-189	846	13	platforms	platform	NOUN
admet-189	846	14	in	in	ADP
admet-189	846	15	parkinson	parkinson	NOUN
admet-189	846	16	’s	’s	PART
admet-189	846	17	disease	disease	NOUN
admet-189	846	18	doi	doi	NOUN
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admet-189	846	21	/	/	SYM
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admet-189	846	26	]	]	PUNCT
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admet-189	846	39	s.	s.	PROPN
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admet-189	846	41	,	,	PUNCT
admet-189	846	42	l.	l.	PROPN
admet-189	846	43	cortes	cortes	PROPN
admet-189	846	44	,	,	PUNCT
admet-189	846	45	j.	j.	PROPN
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admet-189	846	52	l.	l.	PROPN
admet-189	846	53	ferreira	ferreira	PROPN
admet-189	846	54	,	,	PUNCT
admet-189	846	55	l.	l.	PROPN
admet-189	846	56	bernardino	bernardino	PROPN
admet-189	846	57	,	,	PUNCT
admet-189	846	58	acs	acs	PROPN
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admet-189	846	61	(	(	PUNCT
admet-189	846	62	2012	2012	NUM
admet-189	846	63	)	)	PUNCT
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admet-189	846	65	-	-	SYM
admet-189	846	66	10474	10474	NUM
admet-189	846	67	.	.	PUNCT
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admet-189	847	10	y.-x	y.-x	PROPN
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admet-189	848	2	,	,	PUNCT
admet-189	848	3	s.-w	s.-w	PROPN
admet-189	848	4	.	.	PUNCT
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admet-189	849	2	,	,	PUNCT
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admet-189	852	2	.	.	PUNCT
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admet-189	853	7	)	)	PUNCT
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admet-189	853	9	-	-	SYM
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admet-189	853	11	.	.	PUNCT
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admet-189	854	6	,	,	PUNCT
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admet-189	854	9	,	,	PUNCT
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admet-189	855	6	plos	plos	PROPN
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admet-189	855	11	)	)	PUNCT
admet-189	855	12	e84504	e84504	PROPN
admet-189	855	13	.	.	PUNCT
admet-189	856	1	[	[	X
admet-189	856	2	133	133	NUM
admet-189	856	3	]	]	X
admet-189	856	4	a.j	a.j	PROPN
admet-189	856	5	.	.	PROPN
admet-189	856	6	conrad	conrad	PROPN
admet-189	856	7	,	,	PUNCT
admet-189	856	8	(	(	PUNCT
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admet-189	856	13	,	,	PUNCT
admet-189	856	14	us20150065821a1	us20150065821a1	PROPN
admet-189	856	15	(	(	PUNCT
admet-189	856	16	2015	2015	NUM
admet-189	856	17	)	)	PUNCT
admet-189	856	18	.	.	PUNCT
admet-189	857	1	[	[	X
admet-189	857	2	134	134	NUM
admet-189	857	3	]	]	X
admet-189	857	4	r.w	r.w	PROPN
admet-189	857	5	.	.	PROPN
admet-189	857	6	walker	walker	PROPN
admet-189	857	7	,	,	PUNCT
admet-189	857	8	r.	r.	PROPN
admet-189	857	9	zietsma	zietsma	PROPN
admet-189	857	10	,	,	PUNCT
admet-189	857	11	w.k	w.k	PROPN
admet-189	857	12	.	.	PROPN
admet-189	857	13	gray	gray	PROPN
admet-189	857	14	,	,	PUNCT
admet-189	857	15	expert	expert	NOUN
admet-189	857	16	rev	rev	VERB
admet-189	857	17	.	.	PROPN
admet-189	857	18	med	med	PROPN
admet-189	857	19	.	.	PUNCT
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admet-189	858	2	11	11	NUM
admet-189	858	3	(	(	PUNCT
admet-189	858	4	2014	2014	NUM
admet-189	858	5	)	)	PUNCT
admet-189	858	6	243	243	NUM
admet-189	858	7	-	-	SYM
admet-189	858	8	245	245	NUM
admet-189	858	9	.	.	PUNCT
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admet-189	859	11	)	)	PUNCT
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admet-189	859	13	-	-	SYM
admet-189	859	14	68	68	NUM
admet-189	859	15	.	.	PUNCT
admet-189	860	1	[	[	X
admet-189	860	2	136	136	NUM
admet-189	860	3	]	]	X
admet-189	860	4	w.h	w.h	PROPN
admet-189	860	5	.	.	PROPN
admet-189	860	6	de	de	PROPN
admet-189	860	7	jong	jong	PROPN
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admet-189	860	9	p.j	p.j	PROPN
admet-189	860	10	.	.	PROPN
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admet-189	861	1	j.	j.	PROPN
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admet-189	861	6	)	)	PUNCT
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admet-189	861	8	-	-	SYM
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admet-189	861	10	.	.	PUNCT
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admet-189	862	3	]	]	PUNCT
admet-189	862	4	j.	j.	PROPN
admet-189	862	5	kreuter	kreuter	PROPN
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admet-189	862	20	b.	b.	PROPN
admet-189	862	21	engelhardt	engelhardt	PROPN
admet-189	862	22	,	,	PUNCT
admet-189	862	23	r.	r.	PROPN
admet-189	862	24	alyautdin	alyautdin	PROPN
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admet-189	864	2	(	(	PUNCT
admet-189	864	3	2003	2003	NUM
admet-189	864	4	)	)	PUNCT
admet-189	864	5	409	409	NUM
admet-189	864	6	-	-	SYM
admet-189	864	7	416	416	NUM
admet-189	864	8	.	.	PUNCT
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admet-189	865	2	138	138	NUM
admet-189	865	3	]	]	X
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admet-189	865	5	.	.	PROPN
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admet-189	865	12	chauvet	chauvet	PROPN
admet-189	865	13	,	,	PUNCT
admet-189	865	14	c.	c.	PROPN
admet-189	865	15	pariat	pariat	PROPN
admet-189	865	16	,	,	PUNCT
admet-189	865	17	r.	r.	PROPN
admet-189	865	18	cecchelli	cecchelli	PROPN
admet-189	865	19	,	,	PUNCT
admet-189	865	20	w.	w.	PROPN
admet-189	865	21	couet	couet	PROPN
admet-189	865	22	,	,	PUNCT
admet-189	865	23	pharm	pharm	NOUN
admet-189	865	24	.	.	PUNCT
admet-189	866	1	res	re	NOUN
admet-189	866	2	.	.	PUNCT
admet-189	867	1	16	16	NUM
admet-189	867	2	(	(	PUNCT
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admet-189	867	4	)	)	PUNCT
admet-189	867	5	18361842	18361842	NUM
admet-189	867	6	.	.	PUNCT
admet-189	868	1	©	©	PROPN
admet-189	868	2	2015	2015	NUM
admet-189	868	3	by	by	ADP
admet-189	868	4	the	the	DET
admet-189	868	5	authors	author	NOUN
admet-189	868	6	;	;	PUNCT
admet-189	868	7	licensee	licensee	PROPN
admet-189	868	8	iapc	iapc	PROPN
admet-189	868	9	,	,	PUNCT
admet-189	868	10	zagreb	zagreb	PROPN
admet-189	868	11	,	,	PUNCT
admet-189	868	12	croatia	croatia	PROPN
admet-189	868	13	.	.	PUNCT
admet-189	869	1	this	this	DET
admet-189	869	2	article	article	NOUN
admet-189	869	3	is	be	AUX
admet-189	869	4	an	an	DET
admet-189	869	5	open	open	ADJ
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admet-189	869	7	access	access	NOUN
admet-189	869	8	article	article	NOUN
admet-189	869	9	distributed	distribute	VERB
admet-189	869	10	under	under	ADP
admet-189	869	11	the	the	DET
admet-189	869	12	terms	term	NOUN
admet-189	869	13	and	and	CCONJ
admet-189	869	14	conditions	condition	NOUN
admet-189	869	15	of	of	ADP
admet-189	869	16	the	the	DET
admet-189	869	17	creative	creative	ADJ
admet-189	869	18	commons	common	NOUN
admet-189	869	19	attribution	attribution	NOUN
admet-189	869	20	license	license	NOUN
admet-189	869	21	(	(	PUNCT
admet-189	869	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-189	869	23	)	)	PUNCT
admet-189	869	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN