id	sid	tid	token	lemma	pos
admet-19	1	1	manuscript	manuscript	PROPN
admet-19	1	2	doi	doi	PROPN
admet-19	1	3	:	:	PUNCT
admet-19	1	4	10.5599	10.5599	NUM
admet-19	1	5	/	/	SYM
admet-19	1	6	admet.1.4.19	admet.1.4.19	NOUN
admet-19	1	7	76	76	NUM
admet-19	1	8	admet	admet	NOUN
admet-19	1	9	&	&	CCONJ
admet-19	1	10	dmpk	dmpk	PROPN
admet-19	1	11	1(4	1(4	NUM
admet-19	1	12	)	)	PUNCT
admet-19	1	13	(	(	PUNCT
admet-19	1	14	2013	2013	NUM
admet-19	1	15	)	)	PUNCT
admet-19	1	16	76	76	NUM
admet-19	1	17	-	-	SYM
admet-19	1	18	81	81	NUM
admet-19	1	19	;	;	PUNCT
admet-19	1	20	doi	doi	NOUN
admet-19	1	21	:	:	PUNCT
admet-19	1	22	10.5599	10.5599	NUM
admet-19	1	23	/	/	SYM
admet-19	1	24	admet.1.4.19	admet.1.4.19	NOUN
admet-19	1	25	open	open	ADJ
admet-19	1	26	access	access	NOUN
admet-19	1	27	:	:	PUNCT
admet-19	1	28	issn	issn	NOUN
admet-19	1	29	:	:	PUNCT
admet-19	1	30	1848	1848	NUM
admet-19	1	31	-	-	SYM
admet-19	1	32	7718	7718	NUM
admet-19	1	33	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-19	1	34	opinion	opinion	NOUN
admet-19	1	35	on	on	ADP
admet-19	1	36	the	the	DET
admet-19	1	37	evaluation	evaluation	NOUN
admet-19	1	38	of	of	ADP
admet-19	1	39	the	the	DET
admet-19	1	40	safety	safety	NOUN
admet-19	1	41	aspects	aspect	NOUN
admet-19	1	42	of	of	ADP
admet-19	1	43	nanomaterials	nanomaterial	NOUN
admet-19	1	44	in	in	ADP
admet-19	1	45	medical	medical	ADJ
admet-19	1	46	devices	device	NOUN
admet-19	1	47	–	–	PUNCT
admet-19	1	48	a	a	DET
admet-19	1	49	regulatory	regulatory	ADJ
admet-19	1	50	perspective	perspective	NOUN
admet-19	1	51	eva	eva	PROPN
admet-19	1	52	wu	wu	PROPN
admet-19	1	53	,	,	PUNCT
admet-19	1	54	christopher	christopher	PROPN
admet-19	1	55	chan	chan	PROPN
admet-19	1	56	*	*	PROPN
admet-19	1	57	and	and	CCONJ
admet-19	1	58	albert	albert	PROPN
admet-19	1	59	t.w	t.w	PROPN
admet-19	1	60	.	.	PROPN
admet-19	1	61	li	li	PROPN
admet-19	1	62	office	office	PROPN
admet-19	1	63	of	of	ADP
admet-19	1	64	medical	medical	ADJ
admet-19	1	65	device	device	NOUN
admet-19	1	66	evaluation	evaluation	NOUN
admet-19	1	67	,	,	PUNCT
admet-19	1	68	center	center	NOUN
admet-19	1	69	for	for	ADP
admet-19	1	70	measurement	measurement	NOUN
admet-19	1	71	standards	standard	NOUN
admet-19	1	72	,	,	PUNCT
admet-19	1	73	industrial	industrial	ADJ
admet-19	1	74	technology	technology	NOUN
admet-19	1	75	research	research	PROPN
admet-19	1	76	institute	institute	PROPN
admet-19	1	77	,	,	PUNCT
admet-19	1	78	taiwan	taiwan	PROPN
admet-19	1	79	*	*	PUNCT
admet-19	1	80	corresponding	correspond	VERB
admet-19	1	81	author	author	NOUN
admet-19	1	82	:	:	PUNCT
admet-19	1	83	e	e	NOUN
admet-19	1	84	-	-	NOUN
admet-19	1	85	mail	mail	NOUN
admet-19	1	86	:	:	PUNCT
admet-19	1	87	cchan@itri.org.tw	cchan@itri.org.tw	NOUN
admet-19	1	88	;	;	PUNCT
admet-19	1	89	tel	tel	PROPN
admet-19	1	90	.	.	PUNCT
admet-19	1	91	:	:	PUNCT
admet-19	2	1	+886	+886	NUM
admet-19	2	2	-	-	PUNCT
admet-19	2	3	03	03	NUM
admet-19	2	4	-	-	PUNCT
admet-19	2	5	5743836	5743836	NUM
admet-19	2	6	;	;	PUNCT
admet-19	2	7	fax	fax	NOUN
admet-19	2	8	:	:	PUNCT
admet-19	2	9	+886	+886	NUM
admet-19	2	10	-	-	PUNCT
admet-19	2	11	03	03	NUM
admet-19	2	12	-	-	PUNCT
admet-19	2	13	5732299	5732299	NUM
admet-19	2	14	received	receive	VERB
admet-19	2	15	:	:	PUNCT
admet-19	2	16	november	november	PROPN
admet-19	2	17	20	20	NUM
admet-19	2	18	,	,	PUNCT
admet-19	2	19	2013	2013	NUM
admet-19	2	20	;	;	PUNCT
admet-19	2	21	november	november	PROPN
admet-19	2	22	30	30	NUM
admet-19	2	23	,	,	PUNCT
admet-19	2	24	2013	2013	NUM
admet-19	2	25	;	;	PUNCT
admet-19	2	26	published	publish	VERB
admet-19	2	27	:	:	PUNCT
admet-19	2	28	december	december	PROPN
admet-19	2	29	16	16	NUM
admet-19	2	30	,	,	PUNCT
admet-19	2	31	2013	2013	NUM
admet-19	2	32	abstract	abstract	ADJ
admet-19	2	33	nanotechnology	nanotechnology	NOUN
admet-19	2	34	is	be	AUX
admet-19	2	35	widely	widely	ADV
admet-19	2	36	used	use	VERB
admet-19	2	37	in	in	ADP
admet-19	2	38	many	many	ADJ
admet-19	2	39	aspects	aspect	NOUN
admet-19	2	40	of	of	ADP
admet-19	2	41	the	the	DET
admet-19	2	42	design	design	NOUN
admet-19	2	43	and	and	CCONJ
admet-19	2	44	manufacture	manufacture	NOUN
admet-19	2	45	of	of	ADP
admet-19	2	46	medical	medical	ADJ
admet-19	2	47	devices	device	NOUN
admet-19	2	48	.	.	PUNCT
admet-19	3	1	to	to	ADP
admet-19	3	2	date	date	NOUN
admet-19	3	3	,	,	PUNCT
admet-19	3	4	many	many	ADJ
admet-19	3	5	of	of	ADP
admet-19	3	6	these	these	DET
admet-19	3	7	new	new	ADJ
admet-19	3	8	medical	medical	ADJ
admet-19	3	9	devices	device	NOUN
admet-19	3	10	,	,	PUNCT
admet-19	3	11	referred	refer	VERB
admet-19	3	12	to	to	ADP
admet-19	3	13	as	as	ADP
admet-19	3	14	nano	nano	ADJ
admet-19	3	15	medical	medical	ADJ
admet-19	3	16	devices	device	NOUN
admet-19	3	17	,	,	PUNCT
admet-19	3	18	have	have	AUX
admet-19	3	19	been	be	AUX
admet-19	3	20	submitted	submit	VERB
admet-19	3	21	to	to	ADP
admet-19	3	22	health	health	NOUN
admet-19	3	23	authorities	authority	NOUN
admet-19	3	24	for	for	ADP
admet-19	3	25	premarket	premarket	ADJ
admet-19	3	26	regulatory	regulatory	ADJ
admet-19	3	27	review	review	NOUN
admet-19	3	28	.	.	PUNCT
admet-19	4	1	there	there	PRON
admet-19	4	2	are	be	VERB
admet-19	4	3	ongoing	ongoing	ADJ
admet-19	4	4	discussions	discussion	NOUN
admet-19	4	5	between	between	ADP
admet-19	4	6	medical	medical	ADJ
admet-19	4	7	device	device	NOUN
admet-19	4	8	manufacturers	manufacturer	NOUN
admet-19	4	9	and	and	CCONJ
admet-19	4	10	regulatory	regulatory	ADJ
admet-19	4	11	authorities	authority	NOUN
admet-19	4	12	regarding	regard	VERB
admet-19	4	13	the	the	DET
admet-19	4	14	standards	standard	NOUN
admet-19	4	15	and	and	CCONJ
admet-19	4	16	methods	method	NOUN
admet-19	4	17	required	require	VERB
admet-19	4	18	for	for	ADP
admet-19	4	19	the	the	DET
admet-19	4	20	evaluation	evaluation	NOUN
admet-19	4	21	process	process	NOUN
admet-19	4	22	.	.	PUNCT
admet-19	5	1	taking	take	VERB
admet-19	5	2	into	into	ADP
admet-19	5	3	consideration	consideration	NOUN
admet-19	5	4	aspects	aspect	NOUN
admet-19	5	5	including	include	VERB
admet-19	5	6	nano	nano	NOUN
admet-19	5	7	-	-	PUNCT
admet-19	5	8	toxicology	toxicology	NOUN
admet-19	5	9	and	and	CCONJ
admet-19	5	10	biocompatibility	biocompatibility	NOUN
admet-19	5	11	,	,	PUNCT
admet-19	5	12	the	the	DET
admet-19	5	13	clinical	clinical	ADJ
admet-19	5	14	effects	effect	NOUN
admet-19	5	15	of	of	ADP
admet-19	5	16	nanotechnology	nanotechnology	NOUN
admet-19	5	17	and	and	CCONJ
admet-19	5	18	risk	risk	NOUN
admet-19	5	19	management	management	NOUN
admet-19	5	20	,	,	PUNCT
admet-19	5	21	there	there	PRON
admet-19	5	22	are	be	VERB
admet-19	5	23	issues	issue	NOUN
admet-19	5	24	yet	yet	ADV
admet-19	5	25	to	to	PART
admet-19	5	26	be	be	AUX
admet-19	5	27	resolved	resolve	VERB
admet-19	5	28	.	.	PUNCT
admet-19	6	1	in	in	ADP
admet-19	6	2	this	this	DET
admet-19	6	3	article	article	NOUN
admet-19	6	4	,	,	PUNCT
admet-19	6	5	we	we	PRON
admet-19	6	6	will	will	AUX
admet-19	6	7	discuss	discuss	VERB
admet-19	6	8	nano	nano	ADJ
admet-19	6	9	medical	medical	ADJ
admet-19	6	10	device	device	NOUN
admet-19	6	11	safety	safety	NOUN
admet-19	6	12	from	from	ADP
admet-19	6	13	the	the	DET
admet-19	6	14	regulatory	regulatory	ADJ
admet-19	6	15	control	control	NOUN
admet-19	6	16	point	point	NOUN
admet-19	6	17	of	of	ADP
admet-19	6	18	view	view	NOUN
admet-19	6	19	.	.	PUNCT
admet-19	7	1	keywords	keyword	VERB
admet-19	7	2	nanotechnology	nanotechnology	NOUN
admet-19	7	3	;	;	PUNCT
admet-19	7	4	nanomaterial	nanomaterial	NOUN
admet-19	7	5	;	;	PUNCT
admet-19	7	6	regulatory	regulatory	ADJ
admet-19	7	7	;	;	PUNCT
admet-19	7	8	medical	medical	ADJ
admet-19	7	9	device	device	NOUN
admet-19	7	10	;	;	PUNCT
admet-19	7	11	risk	risk	NOUN
admet-19	7	12	management	management	NOUN
admet-19	7	13	;	;	PUNCT
admet-19	7	14	usability	usability	NOUN
admet-19	7	15	.	.	PUNCT
admet-19	8	1	1	1	X
admet-19	8	2	.	.	X
admet-19	8	3	introduction	introduction	NOUN
admet-19	8	4	there	there	PRON
admet-19	8	5	is	be	VERB
admet-19	8	6	no	no	DET
admet-19	8	7	single	single	ADJ
admet-19	8	8	official	official	ADJ
admet-19	8	9	definition	definition	NOUN
admet-19	8	10	of	of	ADP
admet-19	8	11	nanotechnology	nanotechnology	NOUN
admet-19	8	12	in	in	ADP
admet-19	8	13	the	the	DET
admet-19	8	14	application	application	NOUN
admet-19	8	15	of	of	ADP
admet-19	8	16	medical	medical	ADJ
admet-19	8	17	use	use	NOUN
admet-19	8	18	,	,	PUNCT
admet-19	8	19	but	but	CCONJ
admet-19	8	20	the	the	DET
admet-19	8	21	us	us	PROPN
admet-19	8	22	fda	fda	PROPN
admet-19	8	23	refers	refer	VERB
admet-19	8	24	to	to	ADP
admet-19	8	25	nanotechnology	nanotechnology	NOUN
admet-19	8	26	as	as	ADP
admet-19	8	27	engineered	engineer	VERB
admet-19	8	28	materials	material	NOUN
admet-19	8	29	or	or	CCONJ
admet-19	8	30	end	end	NOUN
admet-19	8	31	products	product	NOUN
admet-19	8	32	or	or	CCONJ
admet-19	8	33	the	the	DET
admet-19	8	34	exhibition	exhibition	NOUN
admet-19	8	35	of	of	ADP
admet-19	8	36	properties	property	NOUN
admet-19	8	37	or	or	CCONJ
admet-19	8	38	phenomena	phenomenon	NOUN
admet-19	8	39	that	that	PRON
admet-19	8	40	are	be	AUX
admet-19	8	41	attributable	attributable	ADJ
admet-19	8	42	to	to	ADP
admet-19	8	43	at	at	ADV
admet-19	8	44	least	least	ADJ
admet-19	8	45	one	one	NUM
admet-19	8	46	of	of	ADP
admet-19	8	47	the	the	DET
admet-19	8	48	dimensions	dimension	NOUN
admet-19	8	49	in	in	ADP
admet-19	8	50	the	the	DET
admet-19	8	51	range	range	NOUN
admet-19	8	52	of	of	ADP
admet-19	8	53	1	1	NUM
admet-19	8	54	to	to	PART
admet-19	8	55	100	100	NUM
admet-19	8	56	nanometers	nanometer	NOUN
admet-19	8	57	in	in	ADP
admet-19	8	58	general	general	ADJ
admet-19	8	59	[	[	X
admet-19	8	60	1	1	NUM
admet-19	8	61	]	]	PUNCT
admet-19	8	62	.	.	PUNCT
admet-19	9	1	due	due	ADP
admet-19	9	2	to	to	ADP
admet-19	9	3	these	these	DET
admet-19	9	4	dimensions	dimension	NOUN
admet-19	9	5	,	,	PUNCT
admet-19	9	6	the	the	DET
admet-19	9	7	physical	physical	ADJ
admet-19	9	8	and	and	CCONJ
admet-19	9	9	chemical	chemical	NOUN
admet-19	9	10	,	,	PUNCT
admet-19	9	11	and	and	CCONJ
admet-19	9	12	thereby	thereby	ADV
admet-19	9	13	the	the	DET
admet-19	9	14	biological	biological	ADJ
admet-19	9	15	properties	property	NOUN
admet-19	9	16	of	of	ADP
admet-19	9	17	these	these	DET
admet-19	9	18	materials	material	NOUN
admet-19	9	19	may	may	AUX
admet-19	9	20	not	not	PART
admet-19	9	21	necessarily	necessarily	ADV
admet-19	9	22	be	be	AUX
admet-19	9	23	the	the	DET
admet-19	9	24	same	same	ADJ
admet-19	9	25	as	as	ADP
admet-19	9	26	the	the	DET
admet-19	9	27	same	same	ADJ
admet-19	9	28	material	material	NOUN
admet-19	9	29	in	in	ADP
admet-19	9	30	the	the	DET
admet-19	9	31	bulk	bulk	ADJ
admet-19	9	32	configuration	configuration	NOUN
admet-19	9	33	.	.	PUNCT
admet-19	10	1	the	the	DET
admet-19	10	2	use	use	NOUN
admet-19	10	3	of	of	ADP
admet-19	10	4	nanomaterial	nanomaterial	NOUN
admet-19	10	5	has	have	AUX
admet-19	10	6	been	be	AUX
admet-19	10	7	successfully	successfully	ADV
admet-19	10	8	explored	explore	VERB
admet-19	10	9	in	in	ADP
admet-19	10	10	many	many	ADJ
admet-19	10	11	areas	area	NOUN
admet-19	10	12	such	such	ADJ
admet-19	10	13	as	as	ADP
admet-19	10	14	chemical	chemical	ADJ
admet-19	10	15	materials	material	NOUN
admet-19	10	16	,	,	PUNCT
admet-19	10	17	electronics	electronic	NOUN
admet-19	10	18	,	,	PUNCT
admet-19	10	19	it	it	PRON
admet-19	10	20	and	and	CCONJ
admet-19	10	21	the	the	DET
admet-19	10	22	biomedical	biomedical	ADJ
admet-19	10	23	industry	industry	NOUN
admet-19	10	24	.	.	PUNCT
admet-19	11	1	in	in	ADP
admet-19	11	2	taiwan	taiwan	PROPN
admet-19	11	3	,	,	PUNCT
admet-19	11	4	nano	nano	NOUN
admet-19	11	5	-	-	PUNCT
admet-19	11	6	products	product	NOUN
admet-19	11	7	are	be	AUX
admet-19	11	8	becoming	become	VERB
admet-19	11	9	more	more	ADV
admet-19	11	10	and	and	CCONJ
admet-19	11	11	more	more	ADV
admet-19	11	12	common	common	ADJ
admet-19	11	13	in	in	ADP
admet-19	11	14	the	the	DET
admet-19	11	15	domestic	domestic	ADJ
admet-19	11	16	market	market	NOUN
admet-19	11	17	,	,	PUNCT
admet-19	11	18	including	include	VERB
admet-19	11	19	nano	nano	NOUN
admet-19	11	20	-	-	PUNCT
admet-19	11	21	rags	rag	NOUN
admet-19	11	22	,	,	PUNCT
admet-19	11	23	nano	nano	NOUN
admet-19	11	24	-	-	NOUN
admet-19	11	25	clothing	clothing	NOUN
admet-19	11	26	,	,	PUNCT
admet-19	11	27	nano	nano	NOUN
admet-19	11	28	-	-	PUNCT
admet-19	11	29	silver	silver	ADJ
admet-19	11	30	deodorant	deodorant	NOUN
admet-19	11	31	liquids	liquid	NOUN
admet-19	11	32	,	,	PUNCT
admet-19	11	33	ceramic	ceramic	ADJ
admet-19	11	34	nano	nano	NOUN
admet-19	11	35	-	-	PUNCT
admet-19	11	36	energy	energy	NOUN
admet-19	11	37	cups	cup	NOUN
admet-19	11	38	,	,	PUNCT
admet-19	11	39	nano	nano	NOUN
admet-19	11	40	-	-	PUNCT
admet-19	11	41	toilets	toilet	NOUN
admet-19	11	42	,	,	PUNCT
admet-19	11	43	etc	etc	X
admet-19	11	44	.	.	X
admet-19	11	45	the	the	DET
admet-19	11	46	advertising	advertising	NOUN
admet-19	11	47	of	of	ADP
admet-19	11	48	these	these	DET
admet-19	11	49	products	product	NOUN
admet-19	11	50	infers	infer	NOUN
admet-19	11	51	that	that	SCONJ
admet-19	11	52	they	they	PRON
admet-19	11	53	are	be	AUX
admet-19	11	54	better	well	ADJ
admet-19	11	55	than	than	ADP
admet-19	11	56	their	their	PRON
admet-19	11	57	traditional	traditional	ADJ
admet-19	11	58	counterparts	counterpart	NOUN
admet-19	11	59	with	with	ADP
admet-19	11	60	additional	additional	ADJ
admet-19	11	61	benefits	benefit	NOUN
admet-19	11	62	from	from	ADP
admet-19	11	63	nanotechnology	nanotechnology	NOUN
admet-19	11	64	.	.	PUNCT
admet-19	12	1	it	it	PRON
admet-19	12	2	seems	seem	VERB
admet-19	12	3	that	that	SCONJ
admet-19	12	4	all	all	DET
admet-19	12	5	products	product	NOUN
admet-19	12	6	designated	designate	VERB
admet-19	12	7	as	as	ADP
admet-19	12	8	"	"	PUNCT
admet-19	12	9	nano	nano	NOUN
admet-19	12	10	"	"	PUNCT
admet-19	12	11	will	will	AUX
admet-19	12	12	offer	offer	VERB
admet-19	12	13	some	some	DET
admet-19	12	14	sort	sort	NOUN
admet-19	12	15	of	of	ADP
admet-19	12	16	magical	magical	ADJ
admet-19	12	17	and	and	CCONJ
admet-19	12	18	,	,	PUNCT
admet-19	12	19	more	more	ADV
admet-19	12	20	importantly	importantly	ADV
admet-19	12	21	,	,	PUNCT
admet-19	12	22	beneficial	beneficial	ADJ
admet-19	12	23	effects	effect	NOUN
admet-19	12	24	.	.	PUNCT
admet-19	13	1	consequently	consequently	ADV
admet-19	13	2	,	,	PUNCT
admet-19	13	3	the	the	DET
admet-19	13	4	ministry	ministry	PROPN
admet-19	13	5	of	of	ADP
admet-19	13	6	economic	economic	PROPN
admet-19	13	7	affairs	affair	NOUN
admet-19	13	8	of	of	ADP
admet-19	13	9	taiwan	taiwan	PROPN
admet-19	13	10	has	have	AUX
admet-19	13	11	commissioned	commission	VERB
admet-19	13	12	the	the	DET
admet-19	13	13	center	center	NOUN
admet-19	13	14	for	for	ADP
admet-19	13	15	measurement	measurement	NOUN
admet-19	13	16	standards	standard	NOUN
admet-19	13	17	of	of	ADP
admet-19	13	18	the	the	DET
admet-19	13	19	industrial	industrial	ADJ
admet-19	13	20	technology	technology	PROPN
admet-19	13	21	research	research	PROPN
admet-19	13	22	institute	institute	PROPN
admet-19	13	23	(	(	PUNCT
admet-19	13	24	itri	itri	ADJ
admet-19	13	25	)	)	PUNCT
admet-19	13	26	to	to	PART
admet-19	13	27	assess	assess	VERB
admet-19	13	28	and	and	CCONJ
admet-19	13	29	verify	verify	VERB
admet-19	13	30	the	the	DET
admet-19	13	31	specifications	specification	NOUN
admet-19	13	32	of	of	ADP
admet-19	13	33	nano	nano	NOUN
admet-19	13	34	products	product	NOUN
admet-19	13	35	.	.	PUNCT
admet-19	14	1	a	a	DET
admet-19	14	2	“	"	PUNCT
admet-19	14	3	nanomark	nanomark	NOUN
admet-19	14	4	”	"	PUNCT
admet-19	14	5	will	will	AUX
admet-19	14	6	be	be	AUX
admet-19	14	7	granted	grant	VERB
admet-19	14	8	to	to	ADP
admet-19	14	9	those	those	DET
admet-19	14	10	nano	nano	NOUN
admet-19	14	11	products	product	NOUN
admet-19	14	12	that	that	PRON
admet-19	14	13	meet	meet	VERB
admet-19	14	14	these	these	DET
admet-19	14	15	criteria	criterion	NOUN
admet-19	14	16	.	.	PUNCT
admet-19	15	1	the	the	DET
admet-19	15	2	purpose	purpose	NOUN
admet-19	15	3	of	of	ADP
admet-19	15	4	this	this	DET
admet-19	15	5	assessment	assessment	NOUN
admet-19	15	6	is	be	AUX
admet-19	15	7	to	to	PART
admet-19	15	8	ensure	ensure	VERB
admet-19	15	9	that	that	SCONJ
admet-19	15	10	products	product	NOUN
admet-19	15	11	issued	issue	VERB
admet-19	15	12	with	with	ADP
admet-19	15	13	the	the	DET
admet-19	15	14	“	"	PUNCT
admet-19	15	15	nanomark	nanomark	NOUN
admet-19	15	16	”	"	PUNCT
admet-19	15	17	do	do	AUX
admet-19	15	18	in	in	ADP
admet-19	15	19	fact	fact	NOUN
admet-19	15	20	possess	possess	NOUN
admet-19	15	21	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-19	15	22	admet	admet	PROPN
admet-19	15	23	&	&	CCONJ
admet-19	15	24	dmpk	dmpk	PROPN
admet-19	15	25	1(4	1(4	NUM
admet-19	15	26	)	)	PUNCT
admet-19	15	27	(	(	PUNCT
admet-19	15	28	2013	2013	NUM
admet-19	15	29	)	)	PUNCT
admet-19	15	30	76	76	NUM
admet-19	15	31	-	-	SYM
admet-19	15	32	81	81	NUM
admet-19	15	33	nanomaterials	nanomaterial	NOUN
admet-19	15	34	safety	safety	NOUN
admet-19	15	35	doi	doi	NOUN
admet-19	15	36	:	:	PUNCT
admet-19	15	37	10.5599	10.5599	NUM
admet-19	15	38	/	/	SYM
admet-19	15	39	admet.1.4.19	admet.1.4.19	NOUN
admet-19	15	40	77	77	NUM
admet-19	15	41	certain	certain	ADJ
admet-19	15	42	pre	pre	ADJ
admet-19	15	43	-	-	ADJ
admet-19	15	44	defined	define	VERB
admet-19	15	45	nanotechnology	nanotechnology	NOUN
admet-19	15	46	characteristics	characteristic	NOUN
admet-19	15	47	and	and	CCONJ
admet-19	15	48	scientific	scientific	ADJ
admet-19	15	49	evidence	evidence	NOUN
admet-19	15	50	to	to	PART
admet-19	15	51	support	support	VERB
admet-19	15	52	claims	claim	NOUN
admet-19	15	53	regarding	regard	VERB
admet-19	15	54	pollution	pollution	NOUN
admet-19	15	55	control	control	NOUN
admet-19	15	56	,	,	PUNCT
admet-19	15	57	antibacterial	antibacterial	ADJ
admet-19	15	58	activity	activity	NOUN
admet-19	15	59	,	,	PUNCT
admet-19	15	60	deodorant	deodorant	NOUN
admet-19	15	61	properties	property	NOUN
admet-19	15	62	,	,	PUNCT
admet-19	15	63	wear	wear	NOUN
admet-19	15	64	-	-	PUNCT
admet-19	15	65	resistance	resistance	NOUN
admet-19	15	66	and	and	CCONJ
admet-19	15	67	other	other	ADJ
admet-19	15	68	characteristics	characteristic	NOUN
admet-19	15	69	as	as	SCONJ
admet-19	15	70	described	describe	VERB
admet-19	15	71	in	in	ADP
admet-19	15	72	the	the	DET
admet-19	15	73	product	product	NOUN
admet-19	15	74	specification	specification	NOUN
admet-19	15	75	,	,	PUNCT
admet-19	15	76	in	in	ADP
admet-19	15	77	order	order	NOUN
admet-19	15	78	to	to	PART
admet-19	15	79	protect	protect	VERB
admet-19	15	80	the	the	DET
admet-19	15	81	interests	interest	NOUN
admet-19	15	82	of	of	ADP
admet-19	15	83	consumers	consumer	NOUN
admet-19	15	84	.	.	PUNCT
admet-19	16	1	with	with	ADP
admet-19	16	2	regard	regard	NOUN
admet-19	16	3	to	to	ADP
admet-19	16	4	nano	nano	NOUN
admet-19	16	5	medical	medical	ADJ
admet-19	16	6	devices	device	NOUN
admet-19	16	7	(	(	PUNCT
admet-19	16	8	medical	medical	ADJ
admet-19	16	9	devices	device	NOUN
admet-19	16	10	that	that	PRON
admet-19	16	11	involve	involve	VERB
admet-19	16	12	the	the	DET
admet-19	16	13	use	use	NOUN
admet-19	16	14	of	of	ADP
admet-19	16	15	nanomaterials	nanomaterial	NOUN
admet-19	16	16	or	or	CCONJ
admet-19	16	17	nanotechnology	nanotechnology	NOUN
admet-19	16	18	in	in	ADP
admet-19	16	19	general	general	ADJ
admet-19	16	20	)	)	PUNCT
admet-19	16	21	,	,	PUNCT
admet-19	16	22	safety	safety	NOUN
admet-19	16	23	and	and	CCONJ
admet-19	16	24	efficacy	efficacy	NOUN
admet-19	16	25	are	be	AUX
admet-19	16	26	of	of	ADP
admet-19	16	27	paramount	paramount	ADJ
admet-19	16	28	importance	importance	NOUN
admet-19	16	29	.	.	PUNCT
admet-19	17	1	it	it	PRON
admet-19	17	2	is	be	AUX
admet-19	17	3	necessary	necessary	ADJ
admet-19	17	4	to	to	PART
admet-19	17	5	point	point	VERB
admet-19	17	6	out	out	ADP
admet-19	17	7	that	that	SCONJ
admet-19	17	8	any	any	DET
admet-19	17	9	medical	medical	ADJ
admet-19	17	10	device	device	NOUN
admet-19	17	11	,	,	PUNCT
admet-19	17	12	in	in	ADP
admet-19	17	13	particular	particular	ADJ
admet-19	17	14	those	those	PRON
admet-19	17	15	that	that	PRON
admet-19	17	16	employ	employ	VERB
admet-19	17	17	novel	novel	NOUN
admet-19	17	18	technology	technology	NOUN
admet-19	17	19	like	like	ADP
admet-19	17	20	nanotechnology	nanotechnology	NOUN
admet-19	17	21	in	in	ADP
admet-19	17	22	which	which	PRON
admet-19	17	23	the	the	DET
admet-19	17	24	toxicity	toxicity	NOUN
admet-19	17	25	of	of	ADP
admet-19	17	26	nanomaterials	nanomaterial	NOUN
admet-19	17	27	is	be	AUX
admet-19	17	28	not	not	PART
admet-19	17	29	yet	yet	ADV
admet-19	17	30	fully	fully	ADV
admet-19	17	31	understand	understand	VERB
admet-19	17	32	or	or	CCONJ
admet-19	17	33	there	there	PRON
admet-19	17	34	is	be	VERB
admet-19	17	35	little	little	ADJ
admet-19	17	36	history	history	NOUN
admet-19	17	37	of	of	ADP
admet-19	17	38	a	a	DET
admet-19	17	39	comprehensive	comprehensive	ADJ
admet-19	17	40	evaluation	evaluation	NOUN
admet-19	17	41	of	of	ADP
admet-19	17	42	the	the	DET
admet-19	17	43	technology	technology	NOUN
admet-19	17	44	,	,	PUNCT
admet-19	17	45	their	their	PRON
admet-19	17	46	performance	performance	NOUN
admet-19	17	47	and	and	CCONJ
admet-19	17	48	safety	safety	NOUN
admet-19	17	49	should	should	AUX
admet-19	17	50	be	be	AUX
admet-19	17	51	properly	properly	ADV
admet-19	17	52	evaluated	evaluate	VERB
admet-19	17	53	.	.	PUNCT
admet-19	18	1	it	it	PRON
admet-19	18	2	is	be	AUX
admet-19	18	3	for	for	ADP
admet-19	18	4	this	this	DET
admet-19	18	5	reason	reason	NOUN
admet-19	18	6	that	that	SCONJ
admet-19	18	7	nano	nano	NOUN
admet-19	18	8	medical	medical	ADJ
admet-19	18	9	devices	device	NOUN
admet-19	18	10	have	have	AUX
admet-19	18	11	raised	raise	VERB
admet-19	18	12	the	the	DET
admet-19	18	13	regulatory	regulatory	ADJ
admet-19	18	14	concerns	concern	NOUN
admet-19	18	15	of	of	ADP
admet-19	18	16	the	the	DET
admet-19	18	17	health	health	NOUN
admet-19	18	18	authorities	authority	NOUN
admet-19	18	19	regarding	regard	VERB
admet-19	18	20	safety	safety	NOUN
admet-19	18	21	and	and	CCONJ
admet-19	18	22	efficacy	efficacy	NOUN
admet-19	18	23	.	.	PUNCT
admet-19	19	1	for	for	ADP
admet-19	19	2	example	example	NOUN
admet-19	19	3	,	,	PUNCT
admet-19	19	4	nano	nano	NOUN
admet-19	19	5	-	-	PUNCT
admet-19	19	6	fiber	fiber	NOUN
admet-19	19	7	socks	sock	NOUN
admet-19	19	8	that	that	PRON
admet-19	19	9	are	be	AUX
admet-19	19	10	advertised	advertise	VERB
admet-19	19	11	as	as	ADP
admet-19	19	12	possessing	possess	VERB
admet-19	19	13	antibacterial	antibacterial	ADJ
admet-19	19	14	,	,	PUNCT
admet-19	19	15	deodorant	deodorant	NOUN
admet-19	19	16	and	and	CCONJ
admet-19	19	17	other	other	ADJ
admet-19	19	18	functions	function	NOUN
admet-19	19	19	can	can	AUX
admet-19	19	20	attract	attract	VERB
admet-19	19	21	the	the	DET
admet-19	19	22	attention	attention	NOUN
admet-19	19	23	of	of	ADP
admet-19	19	24	customers	customer	NOUN
admet-19	19	25	and	and	CCONJ
admet-19	19	26	increase	increase	VERB
admet-19	19	27	the	the	DET
admet-19	19	28	selling	selling	NOUN
admet-19	19	29	price	price	NOUN
admet-19	19	30	of	of	ADP
admet-19	19	31	the	the	DET
admet-19	19	32	product	product	NOUN
admet-19	19	33	.	.	PUNCT
admet-19	20	1	however	however	ADV
admet-19	20	2	,	,	PUNCT
admet-19	20	3	the	the	DET
admet-19	20	4	use	use	NOUN
admet-19	20	5	of	of	ADP
admet-19	20	6	such	such	ADJ
admet-19	20	7	products	product	NOUN
admet-19	20	8	for	for	ADP
admet-19	20	9	medical	medical	ADJ
admet-19	20	10	purposes	purpose	NOUN
admet-19	20	11	has	have	AUX
admet-19	20	12	garnered	garner	VERB
admet-19	20	13	the	the	DET
admet-19	20	14	attention	attention	NOUN
admet-19	20	15	from	from	ADP
admet-19	20	16	the	the	DET
admet-19	20	17	health	health	NOUN
admet-19	20	18	authorities	authority	NOUN
admet-19	20	19	,	,	PUNCT
admet-19	20	20	resulting	result	VERB
admet-19	20	21	in	in	ADP
admet-19	20	22	additional	additional	ADJ
admet-19	20	23	safety	safety	NOUN
admet-19	20	24	assessments	assessment	NOUN
admet-19	20	25	on	on	ADP
admet-19	20	26	the	the	DET
admet-19	20	27	nanomaterial	nanomaterial	NOUN
admet-19	20	28	used	use	VERB
admet-19	20	29	before	before	ADP
admet-19	20	30	granting	grant	VERB
admet-19	20	31	marketing	marketing	NOUN
admet-19	20	32	authorization	authorization	NOUN
admet-19	20	33	.	.	PUNCT
admet-19	21	1	in	in	ADP
admet-19	21	2	this	this	DET
admet-19	21	3	context	context	NOUN
admet-19	21	4	,	,	PUNCT
admet-19	21	5	it	it	PRON
admet-19	21	6	is	be	AUX
admet-19	21	7	crucial	crucial	ADJ
admet-19	21	8	to	to	PART
admet-19	21	9	ensure	ensure	VERB
admet-19	21	10	that	that	SCONJ
admet-19	21	11	the	the	DET
admet-19	21	12	nanomaterial	nanomaterial	NOUN
admet-19	21	13	creates	create	VERB
admet-19	21	14	no	no	DET
admet-19	21	15	new	new	ADJ
admet-19	21	16	hazards	hazard	NOUN
admet-19	21	17	to	to	ADP
admet-19	21	18	human	human	ADJ
admet-19	21	19	health	health	NOUN
admet-19	21	20	or	or	CCONJ
admet-19	21	21	the	the	DET
admet-19	21	22	environment	environment	NOUN
admet-19	21	23	compared	compare	VERB
admet-19	21	24	with	with	ADP
admet-19	21	25	the	the	DET
admet-19	21	26	traditional	traditional	ADJ
admet-19	21	27	product	product	NOUN
admet-19	21	28	,	,	PUNCT
admet-19	21	29	and	and	CCONJ
admet-19	21	30	the	the	DET
admet-19	21	31	product	product	NOUN
admet-19	21	32	offers	offer	VERB
admet-19	21	33	the	the	DET
admet-19	21	34	features	feature	NOUN
admet-19	21	35	depicted	depict	VERB
admet-19	21	36	in	in	ADP
admet-19	21	37	the	the	DET
admet-19	21	38	specifications	specification	NOUN
admet-19	21	39	.	.	PUNCT
admet-19	22	1	for	for	ADP
admet-19	22	2	that	that	PRON
admet-19	22	3	,	,	PUNCT
admet-19	22	4	functions	function	NOUN
admet-19	22	5	such	such	ADJ
admet-19	22	6	as	as	ADP
admet-19	22	7	antibacterial	antibacterial	ADJ
admet-19	22	8	and	and	CCONJ
admet-19	22	9	deodorant	deodorant	NOUN
admet-19	22	10	activity	activity	NOUN
admet-19	22	11	may	may	AUX
admet-19	22	12	not	not	PART
admet-19	22	13	seem	seem	VERB
admet-19	22	14	critical	critical	ADJ
admet-19	22	15	compared	compare	VERB
admet-19	22	16	with	with	ADP
admet-19	22	17	a	a	DET
admet-19	22	18	safety	safety	NOUN
admet-19	22	19	evaluation	evaluation	NOUN
admet-19	22	20	.	.	PUNCT
admet-19	23	1	the	the	DET
admet-19	23	2	situation	situation	NOUN
admet-19	23	3	is	be	AUX
admet-19	23	4	further	far	ADV
admet-19	23	5	complicated	complicate	VERB
admet-19	23	6	by	by	ADP
admet-19	23	7	developments	development	NOUN
admet-19	23	8	in	in	ADP
admet-19	23	9	nanotechnology	nanotechnology	NOUN
admet-19	23	10	,	,	PUNCT
admet-19	23	11	whereby	whereby	SCONJ
admet-19	23	12	nanotechnology	nanotechnology	NOUN
admet-19	23	13	applications	application	NOUN
admet-19	23	14	in	in	ADP
admet-19	23	15	different	different	ADJ
admet-19	23	16	disciplines	discipline	NOUN
admet-19	23	17	are	be	AUX
admet-19	23	18	integrated	integrate	VERB
admet-19	23	19	into	into	ADP
admet-19	23	20	a	a	DET
admet-19	23	21	single	single	ADJ
admet-19	23	22	purpose	purpose	NOUN
admet-19	23	23	,	,	PUNCT
admet-19	23	24	like	like	ADP
admet-19	23	25	combination	combination	NOUN
admet-19	23	26	products	product	NOUN
admet-19	23	27	that	that	PRON
admet-19	23	28	combine	combine	VERB
admet-19	23	29	any	any	DET
admet-19	23	30	two	two	NUM
admet-19	23	31	or	or	CCONJ
admet-19	23	32	even	even	ADV
admet-19	23	33	three	three	NUM
admet-19	23	34	of	of	ADP
admet-19	23	35	nanotechnology	nanotechnology	NOUN
admet-19	23	36	utilizing	utilize	VERB
admet-19	23	37	medical	medical	ADJ
admet-19	23	38	devices	device	NOUN
admet-19	23	39	,	,	PUNCT
admet-19	23	40	drugs	drug	NOUN
admet-19	23	41	and	and	CCONJ
admet-19	23	42	biologics	biologic	NOUN
admet-19	23	43	,	,	PUNCT
admet-19	23	44	making	make	VERB
admet-19	23	45	product	product	NOUN
admet-19	23	46	classification	classification	NOUN
admet-19	23	47	difficult	difficult	ADJ
admet-19	23	48	.	.	PUNCT
admet-19	24	1	consequently	consequently	ADV
admet-19	24	2	,	,	PUNCT
admet-19	24	3	the	the	DET
admet-19	24	4	product	product	NOUN
admet-19	24	5	review	review	NOUN
admet-19	24	6	can	can	AUX
admet-19	24	7	be	be	AUX
admet-19	24	8	problematic	problematic	ADJ
admet-19	24	9	.	.	PUNCT
admet-19	25	1	a	a	DET
admet-19	25	2	systematic	systematic	ADJ
admet-19	25	3	and	and	CCONJ
admet-19	25	4	multi	multi	ADJ
admet-19	25	5	-	-	ADJ
admet-19	25	6	disciplinary	disciplinary	ADJ
admet-19	25	7	approach	approach	NOUN
admet-19	25	8	is	be	AUX
admet-19	25	9	therefore	therefore	ADV
admet-19	25	10	necessary	necessary	ADJ
admet-19	25	11	,	,	PUNCT
admet-19	25	12	and	and	CCONJ
admet-19	25	13	particular	particular	ADJ
admet-19	25	14	attention	attention	NOUN
admet-19	25	15	should	should	AUX
admet-19	25	16	be	be	AUX
admet-19	25	17	paid	pay	VERB
admet-19	25	18	during	during	ADP
admet-19	25	19	the	the	DET
admet-19	25	20	regulatory	regulatory	ADJ
admet-19	25	21	review	review	NOUN
admet-19	25	22	of	of	ADP
admet-19	25	23	these	these	DET
admet-19	25	24	products	product	NOUN
admet-19	25	25	.	.	PUNCT
admet-19	26	1	2	2	X
admet-19	26	2	.	.	X
admet-19	26	3	medical	medical	ADJ
admet-19	26	4	applications	application	NOUN
admet-19	26	5	of	of	ADP
admet-19	26	6	nanotechnology	nanotechnology	NOUN
admet-19	26	7	nanomedicine	nanomedicine	PROPN
admet-19	26	8	generally	generally	ADV
admet-19	26	9	refers	refer	VERB
admet-19	26	10	to	to	ADP
admet-19	26	11	the	the	DET
admet-19	26	12	clinical	clinical	ADJ
admet-19	26	13	application	application	NOUN
admet-19	26	14	of	of	ADP
admet-19	26	15	nanotechnology	nanotechnology	NOUN
admet-19	26	16	to	to	PART
admet-19	26	17	provide	provide	VERB
admet-19	26	18	a	a	DET
admet-19	26	19	novel	novel	NOUN
admet-19	26	20	therapy	therapy	NOUN
admet-19	26	21	or	or	CCONJ
admet-19	26	22	diagnosis	diagnosis	NOUN
admet-19	26	23	,	,	PUNCT
admet-19	26	24	including	include	VERB
admet-19	26	25	diagnostic	diagnostic	ADJ
admet-19	26	26	equipment	equipment	NOUN
admet-19	26	27	,	,	PUNCT
admet-19	26	28	drug	drug	NOUN
admet-19	26	29	delivery	delivery	NOUN
admet-19	26	30	devices	device	NOUN
admet-19	26	31	,	,	PUNCT
admet-19	26	32	gene	gene	NOUN
admet-19	26	33	therapy	therapy	NOUN
admet-19	26	34	and	and	CCONJ
admet-19	26	35	tissue	tissue	NOUN
admet-19	26	36	engineering	engineering	NOUN
admet-19	26	37	.	.	PUNCT
admet-19	27	1	in	in	ADP
admet-19	27	2	2003	2003	NUM
admet-19	27	3	,	,	PUNCT
admet-19	27	4	miller	miller	PROPN
admet-19	27	5	recommends	recommend	VERB
admet-19	27	6	the	the	DET
admet-19	27	7	definition	definition	NOUN
admet-19	27	8	of	of	ADP
admet-19	27	9	nanomedicine	nanomedicine	NOUN
admet-19	27	10	as	as	ADP
admet-19	27	11	"	"	PUNCT
admet-19	27	12	the	the	DET
admet-19	27	13	monitoring	monitoring	NOUN
admet-19	27	14	,	,	PUNCT
admet-19	27	15	repair	repair	NOUN
admet-19	27	16	,	,	PUNCT
admet-19	27	17	construction	construction	NOUN
admet-19	27	18	and	and	CCONJ
admet-19	27	19	control	control	NOUN
admet-19	27	20	of	of	ADP
admet-19	27	21	human	human	ADJ
admet-19	27	22	biological	biological	ADJ
admet-19	27	23	systems	system	NOUN
admet-19	27	24	at	at	ADP
admet-19	27	25	the	the	DET
admet-19	27	26	molecular	molecular	ADJ
admet-19	27	27	level	level	NOUN
admet-19	27	28	,	,	PUNCT
admet-19	27	29	using	use	VERB
admet-19	27	30	engineered	engineer	VERB
admet-19	27	31	nanodevices	nanodevice	NOUN
admet-19	27	32	and	and	CCONJ
admet-19	27	33	nanostructures	nanostructure	NOUN
admet-19	27	34	"	"	PUNCT
admet-19	28	1	[	[	X
admet-19	28	2	2	2	NUM
admet-19	28	3	]	]	PUNCT
admet-19	28	4	.	.	PUNCT
admet-19	29	1	as	as	SCONJ
admet-19	29	2	nanotechnology	nanotechnology	NOUN
admet-19	29	3	manipulates	manipulate	VERB
admet-19	29	4	nanostructures	nanostructure	NOUN
admet-19	29	5	at	at	ADP
admet-19	29	6	the	the	DET
admet-19	29	7	molecular	molecular	ADJ
admet-19	29	8	level	level	NOUN
admet-19	29	9	,	,	PUNCT
admet-19	29	10	it	it	PRON
admet-19	29	11	could	could	AUX
admet-19	29	12	potentially	potentially	ADV
admet-19	29	13	generate	generate	VERB
admet-19	29	14	substantial	substantial	ADJ
admet-19	29	15	changes	change	NOUN
admet-19	29	16	in	in	ADP
admet-19	29	17	properties	property	NOUN
admet-19	29	18	such	such	ADJ
admet-19	29	19	as	as	ADP
admet-19	29	20	the	the	DET
admet-19	29	21	melting	melting	NOUN
admet-19	29	22	point	point	NOUN
admet-19	29	23	,	,	PUNCT
admet-19	29	24	electrical	electrical	ADJ
admet-19	29	25	,	,	PUNCT
admet-19	29	26	magnetic	magnetic	ADJ
admet-19	29	27	,	,	PUNCT
admet-19	29	28	optical	optical	ADJ
admet-19	29	29	or	or	CCONJ
admet-19	29	30	surface	surface	NOUN
admet-19	29	31	properties	property	NOUN
admet-19	29	32	and	and	CCONJ
admet-19	29	33	chemical	chemical	NOUN
admet-19	29	34	activity	activity	NOUN
admet-19	29	35	and	and	CCONJ
admet-19	29	36	thereby	thereby	ADV
admet-19	29	37	have	have	VERB
admet-19	29	38	an	an	DET
admet-19	29	39	impact	impact	NOUN
admet-19	29	40	on	on	ADP
admet-19	29	41	the	the	DET
admet-19	29	42	biological	biological	ADJ
admet-19	29	43	properties	property	NOUN
admet-19	29	44	within	within	ADP
admet-19	29	45	a	a	DET
admet-19	29	46	limited	limited	ADJ
admet-19	29	47	space	space	NOUN
admet-19	29	48	.	.	PUNCT
admet-19	30	1	these	these	DET
admet-19	30	2	modifications	modification	NOUN
admet-19	30	3	could	could	AUX
admet-19	30	4	make	make	VERB
admet-19	30	5	products	product	NOUN
admet-19	30	6	that	that	PRON
admet-19	30	7	are	be	AUX
admet-19	30	8	not	not	PART
admet-19	30	9	just	just	ADV
admet-19	30	10	smaller	small	ADJ
admet-19	30	11	but	but	CCONJ
admet-19	30	12	also	also	ADV
admet-19	30	13	lighter	light	ADJ
admet-19	30	14	,	,	PUNCT
admet-19	30	15	more	more	ADV
admet-19	30	16	flexible	flexible	ADJ
admet-19	30	17	,	,	PUNCT
admet-19	30	18	mechanically	mechanically	ADV
admet-19	30	19	stronger	strong	ADJ
admet-19	30	20	,	,	PUNCT
admet-19	30	21	more	more	ADV
admet-19	30	22	sensitive	sensitive	ADJ
admet-19	30	23	,	,	PUNCT
admet-19	30	24	more	more	ADV
admet-19	30	25	selective	selective	ADJ
admet-19	30	26	or	or	CCONJ
admet-19	30	27	more	more	ADV
admet-19	30	28	efficient	efficient	ADJ
admet-19	30	29	.	.	PUNCT
admet-19	31	1	the	the	DET
admet-19	31	2	regulatory	regulatory	ADJ
admet-19	31	3	control	control	NOUN
admet-19	31	4	of	of	ADP
admet-19	31	5	nano	nano	NOUN
admet-19	31	6	medical	medical	ADJ
admet-19	31	7	devices	device	NOUN
admet-19	31	8	should	should	AUX
admet-19	31	9	consider	consider	VERB
admet-19	31	10	the	the	DET
admet-19	31	11	product	product	NOUN
admet-19	31	12	’s	’s	PART
admet-19	31	13	safety	safety	NOUN
admet-19	31	14	,	,	PUNCT
admet-19	31	15	efficacy	efficacy	NOUN
admet-19	31	16	and	and	CCONJ
admet-19	31	17	quality	quality	NOUN
admet-19	31	18	.	.	PUNCT
admet-19	32	1	the	the	DET
admet-19	32	2	safety	safety	NOUN
admet-19	32	3	of	of	ADP
admet-19	32	4	nano	nano	NOUN
admet-19	32	5	products	product	NOUN
admet-19	32	6	is	be	AUX
admet-19	32	7	of	of	ADP
admet-19	32	8	particular	particular	ADJ
admet-19	32	9	importance	importance	NOUN
admet-19	32	10	,	,	PUNCT
admet-19	32	11	especially	especially	ADV
admet-19	32	12	when	when	SCONJ
admet-19	32	13	in	in	ADP
admet-19	32	14	contact	contact	NOUN
admet-19	32	15	with	with	ADP
admet-19	32	16	the	the	DET
admet-19	32	17	surface	surface	NOUN
admet-19	32	18	of	of	ADP
admet-19	32	19	the	the	DET
admet-19	32	20	human	human	ADJ
admet-19	32	21	body	body	NOUN
admet-19	32	22	.	.	PUNCT
admet-19	33	1	additionally	additionally	ADV
admet-19	33	2	,	,	PUNCT
admet-19	33	3	it	it	PRON
admet-19	33	4	is	be	AUX
admet-19	33	5	unclear	unclear	ADJ
admet-19	33	6	whether	whether	SCONJ
admet-19	33	7	or	or	CCONJ
admet-19	33	8	how	how	SCONJ
admet-19	33	9	the	the	DET
admet-19	33	10	absorption	absorption	NOUN
admet-19	33	11	and	and	CCONJ
admet-19	33	12	distribution	distribution	NOUN
admet-19	33	13	of	of	ADP
admet-19	33	14	nanomaterials	nanomaterial	NOUN
admet-19	33	15	in	in	ADP
admet-19	33	16	the	the	DET
admet-19	33	17	human	human	ADJ
admet-19	33	18	body	body	NOUN
admet-19	33	19	would	would	AUX
admet-19	33	20	introduce	introduce	VERB
admet-19	33	21	new	new	ADJ
admet-19	33	22	risks	risk	NOUN
admet-19	33	23	.	.	PUNCT
admet-19	34	1	with	with	ADP
admet-19	34	2	regard	regard	NOUN
admet-19	34	3	to	to	ADP
admet-19	34	4	product	product	NOUN
admet-19	34	5	efficacy	efficacy	NOUN
admet-19	34	6	,	,	PUNCT
admet-19	34	7	the	the	DET
admet-19	34	8	manufacturer	manufacturer	NOUN
admet-19	34	9	should	should	AUX
admet-19	34	10	determine	determine	VERB
admet-19	34	11	the	the	DET
admet-19	34	12	material	material	NOUN
admet-19	34	13	’s	’s	PART
admet-19	34	14	size	size	NOUN
admet-19	34	15	,	,	PUNCT
admet-19	34	16	shape	shape	NOUN
admet-19	34	17	,	,	PUNCT
admet-19	34	18	structure	structure	NOUN
admet-19	34	19	and	and	CCONJ
admet-19	34	20	distribution	distribution	NOUN
admet-19	34	21	to	to	PART
admet-19	34	22	ensure	ensure	VERB
admet-19	34	23	that	that	SCONJ
admet-19	34	24	the	the	DET
admet-19	34	25	nanomaterial	nanomaterial	NOUN
admet-19	34	26	reaches	reach	VERB
admet-19	34	27	the	the	DET
admet-19	34	28	nanoscale	nanoscale	NOUN
admet-19	34	29	,	,	PUNCT
admet-19	34	30	resulting	result	VERB
admet-19	34	31	in	in	ADP
admet-19	34	32	the	the	DET
admet-19	34	33	predetermined	predetermine	VERB
admet-19	34	34	and	and	CCONJ
admet-19	34	35	desired	desire	VERB
admet-19	34	36	new	new	ADJ
admet-19	34	37	properties	property	NOUN
admet-19	34	38	,	,	PUNCT
admet-19	34	39	features	feature	NOUN
admet-19	34	40	or	or	CCONJ
admet-19	34	41	enhancements	enhancement	NOUN
admet-19	34	42	.	.	PUNCT
admet-19	35	1	in	in	ADP
admet-19	35	2	terms	term	NOUN
admet-19	35	3	of	of	ADP
admet-19	35	4	quality	quality	NOUN
admet-19	35	5	,	,	PUNCT
admet-19	35	6	manufacturers	manufacturer	NOUN
admet-19	35	7	should	should	AUX
admet-19	35	8	pay	pay	VERB
admet-19	35	9	attention	attention	NOUN
admet-19	35	10	to	to	ADP
admet-19	35	11	validation	validation	NOUN
admet-19	35	12	,	,	PUNCT
admet-19	35	13	verification	verification	NOUN
admet-19	35	14	,	,	PUNCT
admet-19	35	15	uses	use	VERB
admet-19	35	16	and	and	CCONJ
admet-19	35	17	manufacturing	manufacturing	NOUN
admet-19	35	18	processes	process	NOUN
admet-19	35	19	in	in	ADP
admet-19	35	20	relation	relation	NOUN
admet-19	35	21	to	to	ADP
admet-19	35	22	the	the	DET
admet-19	35	23	nanomaterial	nanomaterial	NOUN
admet-19	35	24	.	.	PUNCT
admet-19	36	1	to	to	PART
admet-19	36	2	sum	sum	VERB
admet-19	36	3	up	up	ADP
admet-19	36	4	,	,	PUNCT
admet-19	36	5	the	the	DET
admet-19	36	6	important	important	ADJ
admet-19	36	7	issues	issue	NOUN
admet-19	36	8	related	relate	VERB
admet-19	36	9	to	to	ADP
admet-19	36	10	the	the	DET
admet-19	36	11	regulatory	regulatory	ADJ
admet-19	36	12	control	control	NOUN
admet-19	36	13	of	of	ADP
admet-19	36	14	nano	nano	NOUN
admet-19	36	15	medical	medical	ADJ
admet-19	36	16	devices	device	NOUN
admet-19	36	17	include	include	VERB
admet-19	36	18	the	the	DET
admet-19	36	19	definition	definition	NOUN
admet-19	36	20	of	of	ADP
admet-19	36	21	the	the	DET
admet-19	36	22	nano	nano	ADJ
admet-19	36	23	medical	medical	ADJ
admet-19	36	24	device	device	NOUN
admet-19	36	25	,	,	PUNCT
admet-19	36	26	classification	classification	NOUN
admet-19	36	27	,	,	PUNCT
admet-19	36	28	premarket	premarket	ADJ
admet-19	36	29	approval	approval	NOUN
admet-19	36	30	procedures	procedure	NOUN
admet-19	36	31	,	,	PUNCT
admet-19	36	32	good	good	ADJ
admet-19	36	33	manufacturing	manufacturing	NOUN
admet-19	36	34	practices	practice	NOUN
admet-19	36	35	,	,	PUNCT
admet-19	36	36	labeling	labeling	NOUN
admet-19	36	37	and	and	CCONJ
admet-19	36	38	postmarket	postmarket	ADJ
admet-19	36	39	authors	author	NOUN
admet-19	36	40	admet	admet	PROPN
admet-19	36	41	&	&	CCONJ
admet-19	36	42	dmpk	dmpk	PROPN
admet-19	36	43	1(4	1(4	NUM
admet-19	36	44	)	)	PUNCT
admet-19	36	45	(	(	PUNCT
admet-19	36	46	2013	2013	NUM
admet-19	36	47	)	)	PUNCT
admet-19	36	48	76	76	NUM
admet-19	36	49	-	-	SYM
admet-19	36	50	81	81	NUM
admet-19	36	51	78	78	NUM
admet-19	36	52	surveillance	surveillance	NOUN
admet-19	36	53	.	.	PUNCT
admet-19	37	1	in	in	ADP
admet-19	37	2	view	view	NOUN
admet-19	37	3	of	of	ADP
admet-19	37	4	the	the	DET
admet-19	37	5	complexity	complexity	NOUN
admet-19	37	6	of	of	ADP
admet-19	37	7	the	the	DET
admet-19	37	8	technology	technology	NOUN
admet-19	37	9	involved	involve	VERB
admet-19	37	10	,	,	PUNCT
admet-19	37	11	it	it	PRON
admet-19	37	12	will	will	AUX
admet-19	37	13	be	be	AUX
admet-19	37	14	a	a	DET
admet-19	37	15	challenge	challenge	NOUN
admet-19	37	16	to	to	PART
admet-19	37	17	establish	establish	VERB
admet-19	37	18	a	a	DET
admet-19	37	19	regulatory	regulatory	ADJ
admet-19	37	20	requirement	requirement	NOUN
admet-19	37	21	and	and	CCONJ
admet-19	37	22	procedure	procedure	NOUN
admet-19	37	23	to	to	PART
admet-19	37	24	control	control	VERB
admet-19	37	25	nano	nano	NOUN
admet-19	37	26	medical	medical	ADJ
admet-19	37	27	devices	device	NOUN
admet-19	37	28	,	,	PUNCT
admet-19	37	29	whether	whether	SCONJ
admet-19	37	30	it	it	PRON
admet-19	37	31	is	be	AUX
admet-19	37	32	a	a	DET
admet-19	37	33	nano	nano	ADJ
admet-19	37	34	medical	medical	ADJ
admet-19	37	35	device	device	NOUN
admet-19	37	36	used	use	VERB
admet-19	37	37	on	on	ADP
admet-19	37	38	its	its	PRON
admet-19	37	39	own	own	ADJ
admet-19	37	40	or	or	CCONJ
admet-19	37	41	in	in	ADP
admet-19	37	42	combination	combination	NOUN
admet-19	37	43	with	with	ADP
admet-19	37	44	other	other	ADJ
admet-19	37	45	equipment	equipment	NOUN
admet-19	37	46	or	or	CCONJ
admet-19	37	47	drugs	drug	NOUN
admet-19	37	48	.	.	PUNCT
admet-19	38	1	ultimately	ultimately	ADV
admet-19	38	2	,	,	PUNCT
admet-19	38	3	the	the	DET
admet-19	38	4	aim	aim	NOUN
admet-19	38	5	of	of	ADP
admet-19	38	6	regulatory	regulatory	ADJ
admet-19	38	7	authorities	authority	NOUN
admet-19	38	8	is	be	AUX
admet-19	38	9	to	to	PART
admet-19	38	10	ensure	ensure	VERB
admet-19	38	11	that	that	SCONJ
admet-19	38	12	the	the	DET
admet-19	38	13	product	product	NOUN
admet-19	38	14	offers	offer	VERB
admet-19	38	15	improved	improved	ADJ
admet-19	38	16	treatment	treatment	NOUN
admet-19	38	17	to	to	ADP
admet-19	38	18	the	the	DET
admet-19	38	19	benefit	benefit	NOUN
admet-19	38	20	of	of	ADP
admet-19	38	21	patients	patient	NOUN
admet-19	38	22	without	without	ADP
admet-19	38	23	incurring	incur	VERB
admet-19	38	24	unacceptable	unacceptable	ADJ
admet-19	38	25	risk	risk	NOUN
admet-19	38	26	.	.	PUNCT
admet-19	39	1	there	there	PRON
admet-19	39	2	are	be	VERB
admet-19	39	3	already	already	ADV
admet-19	39	4	a	a	DET
admet-19	39	5	variety	variety	NOUN
admet-19	39	6	of	of	ADP
admet-19	39	7	nano	nano	NOUN
admet-19	39	8	medical	medical	ADJ
admet-19	39	9	devices	device	NOUN
admet-19	39	10	that	that	PRON
admet-19	39	11	have	have	AUX
admet-19	39	12	been	be	AUX
admet-19	39	13	allowed	allow	VERB
admet-19	39	14	onto	onto	ADP
admet-19	39	15	the	the	DET
admet-19	39	16	market	market	NOUN
admet-19	39	17	by	by	ADP
admet-19	39	18	the	the	DET
admet-19	39	19	us	us	PROPN
admet-19	39	20	fda	fda	PROPN
admet-19	40	1	[	[	X
admet-19	40	2	3	3	NUM
admet-19	40	3	]	]	PUNCT
admet-19	40	4	.	.	PUNCT
admet-19	41	1	generally	generally	ADV
admet-19	41	2	,	,	PUNCT
admet-19	41	3	these	these	DET
admet-19	41	4	products	product	NOUN
admet-19	41	5	serve	serve	VERB
admet-19	41	6	the	the	DET
admet-19	41	7	same	same	ADJ
admet-19	41	8	clinical	clinical	ADJ
admet-19	41	9	purpose	purpose	NOUN
admet-19	41	10	as	as	ADP
admet-19	41	11	the	the	DET
admet-19	41	12	related	relate	VERB
admet-19	41	13	traditional	traditional	ADJ
admet-19	41	14	medical	medical	ADJ
admet-19	41	15	device	device	NOUN
admet-19	41	16	.	.	PUNCT
admet-19	42	1	however	however	ADV
admet-19	42	2	,	,	PUNCT
admet-19	42	3	the	the	DET
admet-19	42	4	incorporation	incorporation	NOUN
admet-19	42	5	of	of	ADP
admet-19	42	6	a	a	DET
admet-19	42	7	nanomaterial	nanomaterial	NOUN
admet-19	42	8	improves	improve	VERB
admet-19	42	9	its	its	PRON
admet-19	42	10	effectiveness	effectiveness	NOUN
admet-19	42	11	,	,	PUNCT
admet-19	42	12	performance	performance	NOUN
admet-19	42	13	or	or	CCONJ
admet-19	42	14	functionality	functionality	NOUN
admet-19	42	15	,	,	PUNCT
admet-19	42	16	such	such	ADJ
admet-19	42	17	as	as	ADP
admet-19	42	18	in	in	ADP
admet-19	42	19	antimicrobial	antimicrobial	ADJ
admet-19	42	20	dressings	dressing	NOUN
admet-19	42	21	,	,	PUNCT
admet-19	42	22	dental	dental	ADJ
admet-19	42	23	materials	material	NOUN
admet-19	42	24	,	,	PUNCT
admet-19	42	25	orthopedic	orthopedic	ADJ
admet-19	42	26	materials	material	NOUN
admet-19	42	27	like	like	ADP
admet-19	42	28	bone	bone	NOUN
admet-19	42	29	cement	cement	NOUN
admet-19	42	30	,	,	PUNCT
admet-19	42	31	and	and	CCONJ
admet-19	42	32	in	in	ADP
admet-19	42	33	vitro	vitro	X
admet-19	42	34	diagnostic	diagnostic	ADJ
admet-19	42	35	reagents	reagent	NOUN
admet-19	42	36	[	[	X
admet-19	42	37	3	3	NUM
admet-19	42	38	]	]	PUNCT
admet-19	42	39	.	.	PUNCT
admet-19	43	1	it	it	PRON
admet-19	43	2	is	be	AUX
admet-19	43	3	the	the	DET
admet-19	43	4	fda	fda	PROPN
admet-19	43	5	’s	’s	PART
admet-19	43	6	current	current	ADJ
admet-19	43	7	thinking	thinking	NOUN
admet-19	43	8	that	that	SCONJ
admet-19	43	9	regulations	regulation	NOUN
admet-19	43	10	can	can	AUX
admet-19	43	11	only	only	ADV
admet-19	43	12	be	be	AUX
admet-19	43	13	based	base	VERB
admet-19	43	14	on	on	ADP
admet-19	43	15	the	the	DET
admet-19	43	16	current	current	ADJ
admet-19	43	17	best	good	ADJ
admet-19	43	18	information	information	NOUN
admet-19	43	19	,	,	PUNCT
admet-19	43	20	and	and	CCONJ
admet-19	43	21	the	the	DET
admet-19	43	22	product	product	NOUN
admet-19	43	23	has	have	VERB
admet-19	43	24	to	to	PART
admet-19	43	25	be	be	AUX
admet-19	43	26	fundamentally	fundamentally	ADV
admet-19	43	27	safe	safe	ADJ
admet-19	43	28	and	and	CCONJ
admet-19	43	29	effective	effective	ADJ
admet-19	43	30	,	,	PUNCT
admet-19	43	31	independent	independent	ADJ
admet-19	43	32	of	of	ADP
admet-19	43	33	whether	whether	SCONJ
admet-19	43	34	the	the	DET
admet-19	43	35	product	product	NOUN
admet-19	43	36	employs	employ	VERB
admet-19	43	37	a	a	DET
admet-19	43	38	nanomaterial	nanomaterial	NOUN
admet-19	43	39	[	[	X
admet-19	43	40	4	4	NUM
admet-19	43	41	-	-	SYM
admet-19	43	42	5	5	NUM
admet-19	43	43	]	]	PUNCT
admet-19	43	44	.	.	PUNCT
admet-19	44	1	the	the	DET
admet-19	44	2	product	product	NOUN
admet-19	44	3	should	should	AUX
admet-19	44	4	,	,	PUNCT
admet-19	44	5	therefore	therefore	ADV
admet-19	44	6	,	,	PUNCT
admet-19	44	7	comply	comply	VERB
admet-19	44	8	with	with	ADP
admet-19	44	9	the	the	DET
admet-19	44	10	basic	basic	ADJ
admet-19	44	11	,	,	PUNCT
admet-19	44	12	relevant	relevant	ADJ
admet-19	44	13	premarket	premarket	NOUN
admet-19	44	14	review	review	NOUN
admet-19	44	15	procedure	procedure	NOUN
admet-19	44	16	and	and	CCONJ
admet-19	44	17	registration	registration	NOUN
admet-19	44	18	regulations	regulation	NOUN
admet-19	44	19	and	and	CCONJ
admet-19	44	20	,	,	PUNCT
admet-19	44	21	if	if	SCONJ
admet-19	44	22	necessary	necessary	ADJ
admet-19	44	23	,	,	PUNCT
admet-19	44	24	comply	comply	ADJ
admet-19	44	25	with	with	ADP
admet-19	44	26	relevant	relevant	ADJ
admet-19	44	27	nanotechnology	nanotechnology	NOUN
admet-19	44	28	evaluations	evaluation	NOUN
admet-19	44	29	like	like	ADP
admet-19	44	30	toxicology	toxicology	NOUN
admet-19	44	31	assessments	assessment	NOUN
admet-19	44	32	.	.	PUNCT
admet-19	45	1	the	the	DET
admet-19	45	2	assessment	assessment	NOUN
admet-19	45	3	of	of	ADP
admet-19	45	4	the	the	DET
admet-19	45	5	safety	safety	NOUN
admet-19	45	6	and	and	CCONJ
admet-19	45	7	effectiveness	effectiveness	NOUN
admet-19	45	8	of	of	ADP
admet-19	45	9	nano	nano	NOUN
admet-19	45	10	medical	medical	ADJ
admet-19	45	11	device	device	NOUN
admet-19	45	12	is	be	AUX
admet-19	45	13	very	very	ADV
admet-19	45	14	much	much	ADV
admet-19	45	15	an	an	DET
admet-19	45	16	ongoing	ongoing	ADJ
admet-19	45	17	development	development	NOUN
admet-19	45	18	process	process	NOUN
admet-19	45	19	for	for	ADP
admet-19	45	20	health	health	NOUN
admet-19	45	21	authorities	authority	NOUN
admet-19	45	22	as	as	ADV
admet-19	45	23	well	well	ADV
admet-19	45	24	as	as	ADP
admet-19	45	25	academia	academia	NOUN
admet-19	45	26	in	in	ADP
admet-19	45	27	many	many	ADJ
admet-19	45	28	countries	country	NOUN
admet-19	45	29	.	.	PUNCT
admet-19	46	1	in	in	ADP
admet-19	46	2	fact	fact	NOUN
admet-19	46	3	,	,	PUNCT
admet-19	46	4	many	many	ADJ
admet-19	46	5	nano	nano	ADJ
admet-19	46	6	medical	medical	ADJ
admet-19	46	7	devices	device	NOUN
admet-19	46	8	that	that	PRON
admet-19	46	9	are	be	AUX
admet-19	46	10	currently	currently	ADV
admet-19	46	11	on	on	ADP
admet-19	46	12	the	the	DET
admet-19	46	13	market	market	NOUN
admet-19	46	14	were	be	AUX
admet-19	46	15	approved	approve	VERB
admet-19	46	16	through	through	ADP
admet-19	46	17	the	the	DET
admet-19	46	18	conventional	conventional	ADJ
admet-19	46	19	medical	medical	ADJ
admet-19	46	20	device	device	NOUN
admet-19	46	21	approval	approval	NOUN
admet-19	46	22	procedure	procedure	NOUN
admet-19	46	23	without	without	ADP
admet-19	46	24	taken	take	VERB
admet-19	46	25	full	full	ADJ
admet-19	46	26	consideration	consideration	NOUN
admet-19	46	27	of	of	ADP
admet-19	46	28	the	the	DET
admet-19	46	29	presence	presence	NOUN
admet-19	46	30	of	of	ADP
admet-19	46	31	the	the	DET
admet-19	46	32	nanomaterial	nanomaterial	NOUN
admet-19	46	33	.	.	PUNCT
admet-19	47	1	having	having	AUX
admet-19	47	2	said	say	VERB
admet-19	47	3	that	that	SCONJ
admet-19	47	4	,	,	PUNCT
admet-19	47	5	some	some	DET
admet-19	47	6	health	health	NOUN
admet-19	47	7	authorities	authority	NOUN
admet-19	47	8	are	be	AUX
admet-19	47	9	becoming	become	VERB
admet-19	47	10	more	more	ADV
admet-19	47	11	aware	aware	ADJ
admet-19	47	12	that	that	SCONJ
admet-19	47	13	the	the	DET
admet-19	47	14	traditional	traditional	ADJ
admet-19	47	15	assessment	assessment	NOUN
admet-19	47	16	approach	approach	NOUN
admet-19	47	17	may	may	AUX
admet-19	47	18	not	not	PART
admet-19	47	19	be	be	AUX
admet-19	47	20	fully	fully	ADV
admet-19	47	21	appropriate	appropriate	ADJ
admet-19	47	22	for	for	ADP
admet-19	47	23	nano	nano	ADJ
admet-19	47	24	medical	medical	ADJ
admet-19	47	25	devices	device	NOUN
admet-19	47	26	,	,	PUNCT
admet-19	47	27	particularly	particularly	ADV
admet-19	47	28	in	in	ADP
admet-19	47	29	terms	term	NOUN
admet-19	47	30	of	of	ADP
admet-19	47	31	assessing	assess	VERB
admet-19	47	32	the	the	DET
admet-19	47	33	risk	risk	NOUN
admet-19	47	34	associated	associate	VERB
admet-19	47	35	with	with	ADP
admet-19	47	36	the	the	DET
admet-19	47	37	nanomaterial	nanomaterial	NOUN
admet-19	47	38	.	.	PUNCT
admet-19	48	1	recent	recent	ADJ
admet-19	48	2	animal	animal	NOUN
admet-19	48	3	studies	study	NOUN
admet-19	48	4	have	have	AUX
admet-19	48	5	also	also	ADV
admet-19	48	6	demonstrated	demonstrate	VERB
admet-19	48	7	that	that	SCONJ
admet-19	48	8	nanomaterials	nanomaterial	NOUN
admet-19	48	9	exhibit	exhibit	VERB
admet-19	48	10	many	many	ADJ
admet-19	48	11	unique	unique	ADJ
admet-19	48	12	toxicological	toxicological	ADJ
admet-19	48	13	properties	property	NOUN
admet-19	48	14	.	.	PUNCT
admet-19	49	1	therefore	therefore	ADV
admet-19	49	2	,	,	PUNCT
admet-19	49	3	in	in	ADP
admet-19	49	4	contrast	contrast	NOUN
admet-19	49	5	with	with	ADP
admet-19	49	6	traditional	traditional	ADJ
admet-19	49	7	products	product	NOUN
admet-19	49	8	,	,	PUNCT
admet-19	49	9	nano	nano	NOUN
admet-19	49	10	medical	medical	ADJ
admet-19	49	11	devices	device	NOUN
admet-19	49	12	require	require	VERB
admet-19	49	13	more	more	ADV
admet-19	49	14	careful	careful	ADJ
admet-19	49	15	consideration	consideration	NOUN
admet-19	49	16	in	in	ADP
admet-19	49	17	the	the	DET
admet-19	49	18	safety	safety	NOUN
admet-19	49	19	assessment	assessment	NOUN
admet-19	49	20	and	and	CCONJ
admet-19	49	21	the	the	DET
admet-19	49	22	development	development	NOUN
admet-19	49	23	of	of	ADP
admet-19	49	24	a	a	DET
admet-19	49	25	standardized	standardized	ADJ
admet-19	49	26	evaluation	evaluation	NOUN
admet-19	49	27	protocol	protocol	NOUN
admet-19	49	28	.	.	PUNCT
admet-19	50	1	in	in	ADP
admet-19	50	2	taiwan	taiwan	PROPN
admet-19	50	3	,	,	PUNCT
admet-19	50	4	the	the	DET
admet-19	50	5	ministry	ministry	PROPN
admet-19	50	6	of	of	ADP
admet-19	50	7	health	health	PROPN
admet-19	50	8	has	have	AUX
admet-19	50	9	expressed	express	VERB
admet-19	50	10	a	a	DET
admet-19	50	11	high	high	ADJ
admet-19	50	12	degree	degree	NOUN
admet-19	50	13	of	of	ADP
admet-19	50	14	concern	concern	NOUN
admet-19	50	15	regarding	regard	VERB
admet-19	50	16	the	the	DET
admet-19	50	17	regulatory	regulatory	ADJ
admet-19	50	18	control	control	NOUN
admet-19	50	19	of	of	ADP
admet-19	50	20	nano	nano	NOUN
admet-19	50	21	medical	medical	ADJ
admet-19	50	22	devices	device	NOUN
admet-19	50	23	,	,	PUNCT
admet-19	50	24	and	and	CCONJ
admet-19	50	25	is	be	AUX
admet-19	50	26	looking	look	VERB
admet-19	50	27	into	into	ADP
admet-19	50	28	the	the	DET
admet-19	50	29	relevant	relevant	ADJ
admet-19	50	30	regulatory	regulatory	ADJ
admet-19	50	31	procedures	procedure	NOUN
admet-19	50	32	for	for	ADP
admet-19	50	33	control	control	NOUN
admet-19	50	34	nano	nano	NOUN
admet-19	50	35	medical	medical	ADJ
admet-19	50	36	devices	device	NOUN
admet-19	50	37	.	.	PUNCT
admet-19	51	1	future	future	ADJ
admet-19	51	2	regulations	regulation	NOUN
admet-19	51	3	for	for	ADP
admet-19	51	4	nano	nano	NOUN
admet-19	51	5	medical	medical	ADJ
admet-19	51	6	devices	device	NOUN
admet-19	51	7	may	may	AUX
admet-19	51	8	include	include	VERB
admet-19	51	9	a	a	DET
admet-19	51	10	pre	pre	ADJ
admet-19	51	11	-	-	ADJ
admet-19	51	12	market	market	ADJ
admet-19	51	13	review	review	NOUN
admet-19	51	14	,	,	PUNCT
admet-19	51	15	quality	quality	NOUN
admet-19	51	16	management	management	NOUN
admet-19	51	17	systems	system	NOUN
admet-19	51	18	and	and	CCONJ
admet-19	51	19	post	post	ADJ
admet-19	51	20	-	-	ADJ
admet-19	51	21	market	market	ADJ
admet-19	51	22	surveillance	surveillance	NOUN
admet-19	51	23	.	.	PUNCT
admet-19	52	1	of	of	ADP
admet-19	52	2	those	those	DET
admet-19	52	3	topics	topic	NOUN
admet-19	52	4	,	,	PUNCT
admet-19	52	5	there	there	PRON
admet-19	52	6	are	be	VERB
admet-19	52	7	issues	issue	NOUN
admet-19	52	8	of	of	ADP
admet-19	52	9	particular	particular	ADJ
admet-19	52	10	interest	interest	NOUN
admet-19	52	11	,	,	PUNCT
admet-19	52	12	including	include	VERB
admet-19	52	13	risk	risk	NOUN
admet-19	52	14	management	management	NOUN
admet-19	52	15	,	,	PUNCT
admet-19	52	16	safety	safety	NOUN
admet-19	52	17	and	and	CCONJ
admet-19	52	18	efficacy	efficacy	NOUN
admet-19	52	19	assessments	assessment	NOUN
admet-19	52	20	,	,	PUNCT
admet-19	52	21	nano	nano	NOUN
admet-19	52	22	process	process	NOUN
admet-19	52	23	validation	validation	NOUN
admet-19	52	24	,	,	PUNCT
admet-19	52	25	labeling	labeling	NOUN
admet-19	52	26	and	and	CCONJ
admet-19	52	27	warning	warning	NOUN
admet-19	52	28	,	,	PUNCT
admet-19	52	29	adverse	adverse	ADJ
admet-19	52	30	event	event	NOUN
admet-19	52	31	reporting	reporting	NOUN
admet-19	52	32	and	and	CCONJ
admet-19	52	33	recall	recall	NOUN
admet-19	52	34	,	,	PUNCT
admet-19	52	35	and	and	CCONJ
admet-19	52	36	monitoring	monitoring	NOUN
admet-19	52	37	.	.	PUNCT
admet-19	53	1	the	the	DET
admet-19	53	2	risk	risk	NOUN
admet-19	53	3	assessment	assessment	NOUN
admet-19	53	4	of	of	ADP
admet-19	53	5	the	the	DET
admet-19	53	6	effects	effect	NOUN
admet-19	53	7	of	of	ADP
admet-19	53	8	nanomaterials	nanomaterial	NOUN
admet-19	53	9	on	on	ADP
admet-19	53	10	public	public	ADJ
admet-19	53	11	health	health	NOUN
admet-19	53	12	should	should	AUX
admet-19	53	13	be	be	AUX
admet-19	53	14	a	a	DET
admet-19	53	15	long	long	ADJ
admet-19	53	16	-	-	PUNCT
admet-19	53	17	term	term	NOUN
admet-19	53	18	,	,	PUNCT
admet-19	53	19	evolving	evolving	NOUN
admet-19	53	20	process	process	NOUN
admet-19	53	21	.	.	PUNCT
admet-19	54	1	it	it	PRON
admet-19	54	2	is	be	AUX
admet-19	54	3	important	important	ADJ
admet-19	54	4	to	to	PART
admet-19	54	5	maintain	maintain	VERB
admet-19	54	6	communication	communication	NOUN
admet-19	54	7	with	with	ADP
admet-19	54	8	experts	expert	NOUN
admet-19	54	9	in	in	ADP
admet-19	54	10	the	the	DET
admet-19	54	11	area	area	NOUN
admet-19	54	12	to	to	PART
admet-19	54	13	ensure	ensure	VERB
admet-19	54	14	the	the	DET
admet-19	54	15	speedy	speedy	ADJ
admet-19	54	16	exchange	exchange	NOUN
admet-19	54	17	of	of	ADP
admet-19	54	18	information	information	NOUN
admet-19	54	19	,	,	PUNCT
admet-19	54	20	and	and	CCONJ
admet-19	54	21	to	to	PART
admet-19	54	22	plan	plan	VERB
admet-19	54	23	and	and	CCONJ
admet-19	54	24	adjust	adjust	VERB
admet-19	54	25	the	the	DET
admet-19	54	26	risk	risk	NOUN
admet-19	54	27	assessment	assessment	NOUN
admet-19	54	28	/	/	SYM
admet-19	54	29	management	management	NOUN
admet-19	54	30	procedure	procedure	NOUN
admet-19	54	31	accordingly	accordingly	ADV
admet-19	54	32	.	.	PUNCT
admet-19	55	1	at	at	ADP
admet-19	55	2	the	the	DET
admet-19	55	3	moment	moment	NOUN
admet-19	55	4	,	,	PUNCT
admet-19	55	5	although	although	SCONJ
admet-19	55	6	the	the	DET
admet-19	55	7	international	international	ADJ
admet-19	55	8	community	community	NOUN
admet-19	55	9	does	do	AUX
admet-19	55	10	not	not	PART
admet-19	55	11	regard	regard	VERB
admet-19	55	12	the	the	DET
admet-19	55	13	development	development	NOUN
admet-19	55	14	of	of	ADP
admet-19	55	15	new	new	ADJ
admet-19	55	16	legislation	legislation	NOUN
admet-19	55	17	for	for	ADP
admet-19	55	18	nano	nano	NOUN
admet-19	55	19	medical	medical	ADJ
admet-19	55	20	devices	device	NOUN
admet-19	55	21	as	as	ADP
admet-19	55	22	being	be	AUX
admet-19	55	23	necessary	necessary	ADJ
admet-19	55	24	,	,	PUNCT
admet-19	55	25	it	it	PRON
admet-19	55	26	is	be	AUX
admet-19	55	27	important	important	ADJ
admet-19	55	28	to	to	PART
admet-19	55	29	pay	pay	VERB
admet-19	55	30	close	close	ADJ
admet-19	55	31	attention	attention	NOUN
admet-19	55	32	to	to	ADP
admet-19	55	33	the	the	DET
admet-19	55	34	development	development	NOUN
admet-19	55	35	of	of	ADP
admet-19	55	36	any	any	DET
admet-19	55	37	international	international	ADJ
admet-19	55	38	standards	standard	NOUN
admet-19	55	39	in	in	ADP
admet-19	55	40	order	order	NOUN
admet-19	55	41	to	to	PART
admet-19	55	42	formulate	formulate	VERB
admet-19	55	43	or	or	CCONJ
admet-19	55	44	adjust	adjust	VERB
admet-19	55	45	the	the	DET
admet-19	55	46	relevant	relevant	ADJ
admet-19	55	47	review	review	NOUN
admet-19	55	48	mechanisms	mechanism	NOUN
admet-19	55	49	.	.	PUNCT
admet-19	56	1	3	3	X
admet-19	56	2	.	.	X
admet-19	56	3	risk	risk	NOUN
admet-19	56	4	assessment	assessment	NOUN
admet-19	56	5	for	for	ADP
admet-19	56	6	nanomaterials	nanomaterial	NOUN
admet-19	56	7	for	for	ADP
admet-19	56	8	the	the	DET
admet-19	56	9	regulatory	regulatory	ADJ
admet-19	56	10	control	control	NOUN
admet-19	56	11	of	of	ADP
admet-19	56	12	nano	nano	NOUN
admet-19	56	13	medical	medical	ADJ
admet-19	56	14	devices	device	NOUN
admet-19	56	15	,	,	PUNCT
admet-19	56	16	in	in	ADP
admet-19	56	17	addition	addition	NOUN
admet-19	56	18	to	to	ADP
admet-19	56	19	regulations	regulation	NOUN
admet-19	56	20	and	and	CCONJ
admet-19	56	21	product	product	NOUN
admet-19	56	22	pre	pre	ADJ
admet-19	56	23	-	-	ADJ
admet-19	56	24	market	market	ADJ
admet-19	56	25	review	review	NOUN
admet-19	56	26	mechanisms	mechanism	NOUN
admet-19	56	27	,	,	PUNCT
admet-19	56	28	risk	risk	NOUN
admet-19	56	29	management	management	NOUN
admet-19	56	30	forms	form	VERB
admet-19	56	31	the	the	DET
admet-19	56	32	basis	basis	NOUN
admet-19	56	33	of	of	ADP
admet-19	56	34	nano	nano	ADJ
admet-19	56	35	medical	medical	ADJ
admet-19	56	36	device	device	NOUN
admet-19	56	37	assessment	assessment	NOUN
admet-19	56	38	and	and	CCONJ
admet-19	56	39	the	the	DET
admet-19	56	40	establishment	establishment	NOUN
admet-19	56	41	of	of	ADP
admet-19	56	42	nano	nano	ADJ
admet-19	56	43	medical	medical	ADJ
admet-19	56	44	device	device	NOUN
admet-19	56	45	regulations	regulation	NOUN
admet-19	56	46	.	.	PUNCT
admet-19	57	1	for	for	ADP
admet-19	57	2	many	many	ADJ
admet-19	57	3	nano	nano	ADJ
admet-19	57	4	medical	medical	ADJ
admet-19	57	5	devices	device	NOUN
admet-19	57	6	,	,	PUNCT
admet-19	57	7	there	there	PRON
admet-19	57	8	is	be	VERB
admet-19	57	9	a	a	DET
admet-19	57	10	fine	fine	ADJ
admet-19	57	11	balance	balance	NOUN
admet-19	57	12	between	between	ADP
admet-19	57	13	risk	risk	NOUN
admet-19	57	14	and	and	CCONJ
admet-19	57	15	effectiveness	effectiveness	NOUN
admet-19	57	16	,	,	PUNCT
admet-19	57	17	especially	especially	ADV
admet-19	57	18	in	in	ADP
admet-19	57	19	the	the	DET
admet-19	57	20	medical	medical	ADJ
admet-19	57	21	field	field	NOUN
admet-19	57	22	where	where	SCONJ
admet-19	57	23	nanomaterials	nanomaterial	NOUN
admet-19	57	24	are	be	AUX
admet-19	57	25	emerging	emerge	VERB
admet-19	57	26	as	as	ADP
admet-19	57	27	a	a	DET
admet-19	57	28	promising	promising	ADJ
admet-19	57	29	approach	approach	NOUN
admet-19	57	30	for	for	ADP
admet-19	57	31	diagnostic	diagnostic	ADJ
admet-19	57	32	technology	technology	NOUN
admet-19	57	33	and	and	CCONJ
admet-19	57	34	new	new	ADJ
admet-19	57	35	treatment	treatment	NOUN
admet-19	57	36	modalities	modality	NOUN
admet-19	57	37	[	[	X
admet-19	57	38	6	6	NUM
admet-19	57	39	]	]	PUNCT
admet-19	57	40	.	.	PUNCT
admet-19	58	1	in	in	ADP
admet-19	58	2	contrast	contrast	NOUN
admet-19	58	3	to	to	ADP
admet-19	58	4	bulk	bulk	ADJ
admet-19	58	5	admet	admet	NOUN
admet-19	58	6	&	&	CCONJ
admet-19	58	7	dmpk	dmpk	PROPN
admet-19	58	8	1(4	1(4	NUM
admet-19	58	9	)	)	PUNCT
admet-19	58	10	(	(	PUNCT
admet-19	58	11	2013	2013	NUM
admet-19	58	12	)	)	PUNCT
admet-19	58	13	76	76	NUM
admet-19	58	14	-	-	SYM
admet-19	58	15	81	81	NUM
admet-19	58	16	nanomaterials	nanomaterial	NOUN
admet-19	58	17	safety	safety	NOUN
admet-19	58	18	doi	doi	NOUN
admet-19	58	19	:	:	PUNCT
admet-19	58	20	10.5599	10.5599	NUM
admet-19	58	21	/	/	SYM
admet-19	58	22	admet.1.4.19	admet.1.4.19	NOUN
admet-19	58	23	79	79	NUM
admet-19	58	24	materials	material	NOUN
admet-19	58	25	,	,	PUNCT
admet-19	58	26	nanomaterials	nanomaterial	NOUN
admet-19	58	27	can	can	AUX
admet-19	58	28	exhibit	exhibit	VERB
admet-19	58	29	very	very	ADV
admet-19	58	30	different	different	ADJ
admet-19	58	31	physical	physical	ADJ
admet-19	58	32	,	,	PUNCT
admet-19	58	33	chemical	chemical	NOUN
admet-19	58	34	and	and	CCONJ
admet-19	58	35	biological	biological	ADJ
admet-19	58	36	properties	property	NOUN
admet-19	58	37	that	that	PRON
admet-19	58	38	differ	differ	VERB
admet-19	58	39	from	from	ADP
admet-19	58	40	expectation	expectation	NOUN
admet-19	58	41	,	,	PUNCT
admet-19	58	42	which	which	PRON
admet-19	58	43	could	could	AUX
admet-19	58	44	result	result	VERB
admet-19	58	45	in	in	ADP
admet-19	58	46	new	new	ADJ
admet-19	58	47	risks	risk	NOUN
admet-19	58	48	that	that	PRON
admet-19	58	49	need	need	VERB
admet-19	58	50	proper	proper	ADJ
admet-19	58	51	evaluation	evaluation	NOUN
admet-19	58	52	and	and	CCONJ
admet-19	58	53	even	even	ADV
admet-19	58	54	control	control	NOUN
admet-19	58	55	before	before	SCONJ
admet-19	58	56	marketing	marketing	NOUN
admet-19	58	57	is	be	AUX
admet-19	58	58	permitted	permit	VERB
admet-19	58	59	.	.	PUNCT
admet-19	59	1	there	there	PRON
admet-19	59	2	is	be	VERB
admet-19	59	3	currently	currently	ADV
admet-19	59	4	no	no	DET
admet-19	59	5	specific	specific	ADJ
admet-19	59	6	standard	standard	NOUN
admet-19	59	7	for	for	ADP
admet-19	59	8	risk	risk	NOUN
admet-19	59	9	management	management	NOUN
admet-19	59	10	regarding	regard	VERB
admet-19	59	11	nano	nano	ADJ
admet-19	59	12	medical	medical	ADJ
admet-19	59	13	devices	device	NOUN
admet-19	59	14	;	;	PUNCT
admet-19	59	15	however	however	ADV
admet-19	59	16	,	,	PUNCT
admet-19	59	17	the	the	DET
admet-19	59	18	international	international	ADJ
admet-19	59	19	standard	standard	ADJ
admet-19	59	20	iso	iso	NOUN
admet-19	59	21	14971	14971	NUM
admet-19	59	22	(	(	PUNCT
admet-19	59	23	medical	medical	ADJ
admet-19	59	24	devices	device	NOUN
admet-19	59	25	–	–	PUNCT
admet-19	59	26	application	application	NOUN
admet-19	59	27	of	of	ADP
admet-19	59	28	risk	risk	NOUN
admet-19	59	29	management	management	NOUN
admet-19	59	30	to	to	ADP
admet-19	59	31	medical	medical	ADJ
admet-19	59	32	devices	device	NOUN
admet-19	59	33	)	)	PUNCT
admet-19	59	34	could	could	AUX
admet-19	59	35	be	be	AUX
admet-19	59	36	used	use	VERB
admet-19	59	37	for	for	ADP
admet-19	59	38	this	this	DET
admet-19	59	39	purpose	purpose	NOUN
admet-19	59	40	.	.	PUNCT
admet-19	60	1	like	like	ADP
admet-19	60	2	traditional	traditional	ADJ
admet-19	60	3	medical	medical	ADJ
admet-19	60	4	devices	device	NOUN
admet-19	60	5	,	,	PUNCT
admet-19	60	6	the	the	DET
admet-19	60	7	existing	exist	VERB
admet-19	60	8	standard	standard	ADJ
admet-19	60	9	operating	operating	NOUN
admet-19	60	10	procedures	procedure	NOUN
admet-19	60	11	can	can	AUX
admet-19	60	12	be	be	AUX
admet-19	60	13	used	use	VERB
admet-19	60	14	,	,	PUNCT
admet-19	60	15	with	with	ADP
admet-19	60	16	special	special	ADJ
admet-19	60	17	attention	attention	NOUN
admet-19	60	18	paid	pay	VERB
admet-19	60	19	to	to	ADP
admet-19	60	20	potential	potential	ADJ
admet-19	60	21	hazards	hazard	NOUN
admet-19	60	22	related	relate	VERB
admet-19	60	23	to	to	ADP
admet-19	60	24	the	the	DET
admet-19	60	25	properties	property	NOUN
admet-19	60	26	and	and	CCONJ
admet-19	60	27	phenomena	phenomenon	NOUN
admet-19	60	28	that	that	PRON
admet-19	60	29	can	can	AUX
admet-19	60	30	result	result	VERB
admet-19	60	31	from	from	ADP
admet-19	60	32	the	the	DET
admet-19	60	33	nanomaterial	nanomaterial	NOUN
admet-19	60	34	or	or	CCONJ
admet-19	60	35	nanostructure	nanostructure	NOUN
admet-19	60	36	.	.	PUNCT
admet-19	61	1	these	these	DET
admet-19	61	2	potential	potential	ADJ
admet-19	61	3	hazards	hazard	NOUN
admet-19	61	4	should	should	AUX
admet-19	61	5	be	be	AUX
admet-19	61	6	first	first	ADV
admet-19	61	7	identified	identify	VERB
admet-19	61	8	,	,	PUNCT
admet-19	61	9	estimated	estimate	VERB
admet-19	61	10	and	and	CCONJ
admet-19	61	11	evaluated	evaluate	VERB
admet-19	61	12	according	accord	VERB
admet-19	61	13	to	to	ADP
admet-19	61	14	the	the	DET
admet-19	61	15	predefined	predefine	VERB
admet-19	61	16	risk	risk	NOUN
admet-19	61	17	acceptance	acceptance	NOUN
admet-19	61	18	criteria	criterion	NOUN
admet-19	61	19	.	.	PUNCT
admet-19	62	1	if	if	SCONJ
admet-19	62	2	necessary	necessary	ADJ
admet-19	62	3	,	,	PUNCT
admet-19	62	4	risk	risk	NOUN
admet-19	62	5	control	control	NOUN
admet-19	62	6	measures	measure	NOUN
admet-19	62	7	should	should	AUX
admet-19	62	8	be	be	AUX
admet-19	62	9	implemented	implement	VERB
admet-19	62	10	,	,	PUNCT
admet-19	62	11	thereby	thereby	ADV
admet-19	62	12	ultimately	ultimately	ADV
admet-19	62	13	ensuring	ensure	VERB
admet-19	62	14	that	that	SCONJ
admet-19	62	15	the	the	DET
admet-19	62	16	product	product	NOUN
admet-19	62	17	’s	’s	PART
admet-19	62	18	benefits	benefit	NOUN
admet-19	62	19	outweigh	outweigh	VERB
admet-19	62	20	the	the	DET
admet-19	62	21	risk	risk	NOUN
admet-19	62	22	[	[	X
admet-19	62	23	7	7	NUM
admet-19	62	24	]	]	PUNCT
admet-19	62	25	.	.	PUNCT
admet-19	63	1	the	the	DET
admet-19	63	2	identification	identification	NOUN
admet-19	63	3	of	of	ADP
admet-19	63	4	nano	nano	NOUN
admet-19	63	5	-	-	PUNCT
admet-19	63	6	hazards	hazard	NOUN
admet-19	63	7	requires	require	VERB
admet-19	63	8	in	in	ADP
admet-19	63	9	-	-	PUNCT
admet-19	63	10	depth	depth	NOUN
admet-19	63	11	and	and	CCONJ
admet-19	63	12	in	in	ADP
admet-19	63	13	some	some	DET
admet-19	63	14	cases	case	NOUN
admet-19	63	15	multidisciplinary	multidisciplinary	ADJ
admet-19	63	16	knowledge	knowledge	NOUN
admet-19	63	17	of	of	ADP
admet-19	63	18	the	the	DET
admet-19	63	19	product	product	NOUN
admet-19	63	20	’s	’s	PART
admet-19	63	21	technology	technology	NOUN
admet-19	63	22	,	,	PUNCT
admet-19	63	23	application	application	NOUN
admet-19	63	24	environment	environment	NOUN
admet-19	63	25	,	,	PUNCT
admet-19	63	26	regulatory	regulatory	ADJ
admet-19	63	27	requirements	requirement	NOUN
admet-19	63	28	and	and	CCONJ
admet-19	63	29	even	even	ADV
admet-19	63	30	usability	usability	NOUN
admet-19	63	31	.	.	PUNCT
admet-19	64	1	nano	nano	PROPN
admet-19	64	2	medical	medical	ADJ
admet-19	64	3	devices	device	NOUN
admet-19	64	4	may	may	AUX
admet-19	64	5	on	on	ADP
admet-19	64	6	first	first	ADJ
admet-19	64	7	appearance	appearance	NOUN
admet-19	64	8	look	look	VERB
admet-19	64	9	exactly	exactly	ADV
admet-19	64	10	the	the	DET
admet-19	64	11	same	same	ADJ
admet-19	64	12	as	as	ADP
admet-19	64	13	their	their	PRON
admet-19	64	14	traditional	traditional	ADJ
admet-19	64	15	counterparts	counterpart	NOUN
admet-19	64	16	,	,	PUNCT
admet-19	64	17	but	but	CCONJ
admet-19	64	18	for	for	ADP
admet-19	64	19	this	this	DET
admet-19	64	20	exact	exact	ADJ
admet-19	64	21	reason	reason	NOUN
admet-19	64	22	,	,	PUNCT
admet-19	64	23	their	their	PRON
admet-19	64	24	usability	usability	NOUN
admet-19	64	25	becomes	become	VERB
admet-19	64	26	very	very	ADV
admet-19	64	27	important	important	ADJ
admet-19	64	28	and	and	CCONJ
admet-19	64	29	the	the	DET
admet-19	64	30	use	use	NOUN
admet-19	64	31	hazards	hazard	NOUN
admet-19	64	32	should	should	AUX
admet-19	64	33	be	be	AUX
admet-19	64	34	properly	properly	ADV
admet-19	64	35	evaluated	evaluate	VERB
admet-19	64	36	if	if	SCONJ
admet-19	64	37	necessary	necessary	ADJ
admet-19	64	38	,	,	PUNCT
admet-19	64	39	as	as	SCONJ
admet-19	64	40	usage	usage	NOUN
admet-19	64	41	error	error	NOUN
admet-19	64	42	may	may	AUX
admet-19	64	43	result	result	VERB
admet-19	64	44	from	from	ADP
admet-19	64	45	failure	failure	NOUN
admet-19	64	46	to	to	PART
admet-19	64	47	tell	tell	VERB
admet-19	64	48	the	the	DET
admet-19	64	49	nano	nano	NOUN
admet-19	64	50	device	device	NOUN
admet-19	64	51	from	from	ADP
admet-19	64	52	the	the	DET
admet-19	64	53	traditional	traditional	ADJ
admet-19	64	54	product	product	NOUN
admet-19	64	55	.	.	PUNCT
admet-19	65	1	the	the	DET
admet-19	65	2	use	use	NOUN
admet-19	65	3	of	of	ADP
admet-19	65	4	standards	standard	NOUN
admet-19	65	5	like	like	ADP
admet-19	65	6	iso	iso	NOUN
admet-19	65	7	/	/	SYM
admet-19	65	8	iec	iec	PROPN
admet-19	65	9	62366	62366	NUM
admet-19	66	1	[	[	X
admet-19	66	2	8	8	NUM
admet-19	66	3	]	]	PUNCT
admet-19	66	4	and	and	CCONJ
admet-19	66	5	ansi	ansi	PROPN
admet-19	66	6	/	/	SYM
admet-19	66	7	aami	aami	PROPN
admet-19	66	8	he75	he75	PROPN
admet-19	66	9	[	[	X
admet-19	66	10	9	9	NUM
admet-19	66	11	]	]	PUNCT
admet-19	66	12	are	be	AUX
admet-19	66	13	just	just	ADV
admet-19	66	14	some	some	PRON
admet-19	66	15	of	of	ADP
admet-19	66	16	the	the	DET
admet-19	66	17	best	good	ADJ
admet-19	66	18	currently	currently	ADV
admet-19	66	19	available	available	ADJ
admet-19	66	20	tools	tool	NOUN
admet-19	66	21	to	to	PART
admet-19	66	22	address	address	VERB
admet-19	66	23	the	the	DET
admet-19	66	24	usability	usability	NOUN
admet-19	66	25	issue	issue	NOUN
admet-19	66	26	.	.	PUNCT
admet-19	67	1	the	the	DET
admet-19	67	2	identification	identification	NOUN
admet-19	67	3	of	of	ADP
admet-19	67	4	hazards	hazard	NOUN
admet-19	67	5	can	can	AUX
admet-19	67	6	be	be	AUX
admet-19	67	7	performed	perform	VERB
admet-19	67	8	systematically	systematically	ADV
admet-19	67	9	according	accord	VERB
admet-19	67	10	to	to	ADP
admet-19	67	11	the	the	DET
admet-19	67	12	different	different	ADJ
admet-19	67	13	characteristics	characteristic	NOUN
admet-19	67	14	of	of	ADP
admet-19	67	15	the	the	DET
admet-19	67	16	nanomaterial	nanomaterial	NOUN
admet-19	67	17	.	.	PUNCT
admet-19	68	1	for	for	ADP
admet-19	68	2	a	a	DET
admet-19	68	3	nanomaterial	nanomaterial	NOUN
admet-19	68	4	with	with	ADP
admet-19	68	5	a	a	DET
admet-19	68	6	novel	novel	ADJ
admet-19	68	7	structure	structure	NOUN
admet-19	68	8	,	,	PUNCT
admet-19	68	9	the	the	DET
admet-19	68	10	hazards	hazard	NOUN
admet-19	68	11	are	be	AUX
admet-19	68	12	usually	usually	ADV
admet-19	68	13	more	more	ADV
admet-19	68	14	difficult	difficult	ADJ
admet-19	68	15	to	to	PART
admet-19	68	16	predict	predict	VERB
admet-19	68	17	(	(	PUNCT
admet-19	68	18	as	as	SCONJ
admet-19	68	19	compared	compare	VERB
admet-19	68	20	with	with	ADP
admet-19	68	21	a	a	DET
admet-19	68	22	micronized	micronized	ADJ
admet-19	68	23	material	material	NOUN
admet-19	68	24	such	such	ADJ
admet-19	68	25	as	as	ADP
admet-19	68	26	metal	metal	NOUN
admet-19	68	27	oxide	oxide	NOUN
admet-19	68	28	,	,	PUNCT
admet-19	68	29	titanium	titanium	NOUN
admet-19	68	30	dioxide	dioxide	NOUN
admet-19	68	31	or	or	CCONJ
admet-19	68	32	zinc	zinc	NOUN
admet-19	68	33	oxide	oxide	NOUN
admet-19	68	34	)	)	PUNCT
admet-19	68	35	.	.	PUNCT
admet-19	69	1	in	in	ADP
admet-19	69	2	cases	case	NOUN
admet-19	69	3	where	where	SCONJ
admet-19	69	4	these	these	DET
admet-19	69	5	nanomaterials	nanomaterial	NOUN
admet-19	69	6	are	be	AUX
admet-19	69	7	enclosed	enclose	VERB
admet-19	69	8	within	within	ADP
admet-19	69	9	a	a	DET
admet-19	69	10	surface	surface	NOUN
admet-19	69	11	coating	coating	NOUN
admet-19	69	12	or	or	CCONJ
admet-19	69	13	matrix	matrix	NOUN
admet-19	69	14	material	material	NOUN
admet-19	69	15	,	,	PUNCT
admet-19	69	16	the	the	DET
admet-19	69	17	biological	biological	ADJ
admet-19	69	18	reactivity	reactivity	NOUN
admet-19	69	19	and	and	CCONJ
admet-19	69	20	mobility	mobility	NOUN
admet-19	69	21	will	will	AUX
admet-19	69	22	be	be	AUX
admet-19	69	23	contained	contain	VERB
admet-19	69	24	.	.	PUNCT
admet-19	70	1	however	however	ADV
admet-19	70	2	,	,	PUNCT
admet-19	70	3	the	the	DET
admet-19	70	4	durability	durability	NOUN
admet-19	70	5	of	of	ADP
admet-19	70	6	the	the	DET
admet-19	70	7	enclosure	enclosure	NOUN
admet-19	70	8	would	would	AUX
admet-19	70	9	then	then	ADV
admet-19	70	10	need	need	VERB
admet-19	70	11	to	to	PART
admet-19	70	12	be	be	AUX
admet-19	70	13	considered	consider	VERB
admet-19	70	14	in	in	ADP
admet-19	70	15	order	order	NOUN
admet-19	70	16	to	to	PART
admet-19	70	17	avoid	avoid	VERB
admet-19	70	18	the	the	DET
admet-19	70	19	unexpected	unexpected	ADJ
admet-19	70	20	leaching	leaching	NOUN
admet-19	70	21	of	of	ADP
admet-19	70	22	these	these	DET
admet-19	70	23	nanomaterials	nanomaterial	NOUN
admet-19	70	24	into	into	ADP
admet-19	70	25	the	the	DET
admet-19	70	26	environment	environment	NOUN
admet-19	70	27	.	.	PUNCT
admet-19	71	1	toxicology	toxicology	NOUN
admet-19	71	2	is	be	AUX
admet-19	71	3	obviously	obviously	ADV
admet-19	71	4	a	a	DET
admet-19	71	5	major	major	ADJ
admet-19	71	6	risk	risk	NOUN
admet-19	71	7	of	of	ADP
admet-19	71	8	nanotechnology	nanotechnology	NOUN
admet-19	71	9	that	that	PRON
admet-19	71	10	needs	need	VERB
admet-19	71	11	to	to	PART
admet-19	71	12	be	be	AUX
admet-19	71	13	addressed	address	VERB
admet-19	71	14	.	.	PUNCT
admet-19	72	1	nanotoxicology	nanotoxicology	NOUN
admet-19	72	2	risks	risk	NOUN
admet-19	72	3	are	be	AUX
admet-19	72	4	still	still	ADV
admet-19	72	5	very	very	ADV
admet-19	72	6	much	much	ADV
admet-19	72	7	debatable	debatable	ADJ
admet-19	72	8	issues	issue	NOUN
admet-19	72	9	,	,	PUNCT
admet-19	72	10	and	and	CCONJ
admet-19	72	11	most	most	ADJ
admet-19	72	12	result	result	VERB
admet-19	72	13	from	from	ADP
admet-19	72	14	various	various	ADJ
admet-19	72	15	pathways	pathway	NOUN
admet-19	72	16	of	of	ADP
admet-19	72	17	adsorption	adsorption	NOUN
admet-19	72	18	into	into	ADP
admet-19	72	19	the	the	DET
admet-19	72	20	body	body	NOUN
admet-19	72	21	.	.	PUNCT
admet-19	73	1	therefore	therefore	ADV
admet-19	73	2	,	,	PUNCT
admet-19	73	3	a	a	DET
admet-19	73	4	nanomaterial	nanomaterial	NOUN
admet-19	73	5	unexpectedly	unexpectedly	ADV
admet-19	73	6	or	or	CCONJ
admet-19	73	7	uncontrollably	uncontrollably	ADV
admet-19	73	8	entering	enter	VERB
admet-19	73	9	the	the	DET
admet-19	73	10	human	human	ADJ
admet-19	73	11	body	body	NOUN
admet-19	73	12	through	through	ADP
admet-19	73	13	the	the	DET
admet-19	73	14	skin	skin	NOUN
admet-19	73	15	or	or	CCONJ
admet-19	73	16	by	by	ADP
admet-19	73	17	inhalation	inhalation	NOUN
admet-19	73	18	is	be	AUX
admet-19	73	19	a	a	DET
admet-19	73	20	concern	concern	NOUN
admet-19	73	21	.	.	PUNCT
admet-19	74	1	research	research	NOUN
admet-19	74	2	studies	study	NOUN
admet-19	74	3	have	have	AUX
admet-19	74	4	shown	show	VERB
admet-19	74	5	that	that	SCONJ
admet-19	74	6	as	as	ADP
admet-19	74	7	a	a	DET
admet-19	74	8	material	material	NOUN
admet-19	74	9	’s	’s	PART
admet-19	74	10	particle	particle	NOUN
admet-19	74	11	size	size	NOUN
admet-19	74	12	becomes	become	VERB
admet-19	74	13	smaller	small	ADJ
admet-19	74	14	,	,	PUNCT
admet-19	74	15	the	the	DET
admet-19	74	16	total	total	ADJ
admet-19	74	17	surface	surface	NOUN
admet-19	74	18	area	area	NOUN
admet-19	74	19	of	of	ADP
admet-19	74	20	the	the	DET
admet-19	74	21	potentially	potentially	ADV
admet-19	74	22	inhaled	inhaled	ADJ
admet-19	74	23	or	or	CCONJ
admet-19	74	24	adsorbed	adsorb	VERB
admet-19	74	25	particles	particle	NOUN
admet-19	74	26	becomes	become	VERB
admet-19	74	27	greater	great	ADJ
admet-19	74	28	,	,	PUNCT
admet-19	74	29	leading	lead	VERB
admet-19	74	30	to	to	ADP
admet-19	74	31	increased	increase	VERB
admet-19	74	32	toxicity	toxicity	NOUN
admet-19	74	33	[	[	X
admet-19	74	34	10	10	NUM
admet-19	74	35	]	]	PUNCT
admet-19	74	36	.	.	PUNCT
admet-19	75	1	airborne	airborne	ADJ
admet-19	75	2	nanomaterials	nanomaterial	NOUN
admet-19	75	3	are	be	AUX
admet-19	75	4	often	often	ADV
admet-19	75	5	the	the	DET
admet-19	75	6	main	main	ADJ
admet-19	75	7	culprit	culprit	NOUN
admet-19	75	8	in	in	ADP
admet-19	75	9	terms	term	NOUN
admet-19	75	10	of	of	ADP
admet-19	75	11	toxicity	toxicity	NOUN
admet-19	75	12	.	.	PUNCT
admet-19	76	1	in	in	ADP
admet-19	76	2	order	order	NOUN
admet-19	76	3	to	to	PART
admet-19	76	4	assess	assess	VERB
admet-19	76	5	the	the	DET
admet-19	76	6	effects	effect	NOUN
admet-19	76	7	of	of	ADP
admet-19	76	8	exposure	exposure	NOUN
admet-19	76	9	,	,	PUNCT
admet-19	76	10	adsorption	adsorption	NOUN
admet-19	76	11	,	,	PUNCT
admet-19	76	12	transport	transport	NOUN
admet-19	76	13	and	and	CCONJ
admet-19	76	14	distribution	distribution	NOUN
admet-19	76	15	within	within	ADP
admet-19	76	16	the	the	DET
admet-19	76	17	human	human	ADJ
admet-19	76	18	body	body	NOUN
admet-19	76	19	,	,	PUNCT
admet-19	76	20	various	various	ADJ
admet-19	76	21	factors	factor	NOUN
admet-19	76	22	need	need	VERB
admet-19	76	23	to	to	PART
admet-19	76	24	be	be	AUX
admet-19	76	25	taken	take	VERB
admet-19	76	26	into	into	ADP
admet-19	76	27	consideration	consideration	NOUN
admet-19	76	28	,	,	PUNCT
admet-19	76	29	including	include	VERB
admet-19	76	30	the	the	DET
admet-19	76	31	particle	particle	NOUN
admet-19	76	32	concentration	concentration	NOUN
admet-19	76	33	in	in	ADP
admet-19	76	34	air	air	NOUN
admet-19	76	35	,	,	PUNCT
admet-19	76	36	particle	particle	NOUN
admet-19	76	37	size	size	NOUN
admet-19	76	38	,	,	PUNCT
admet-19	76	39	shape	shape	NOUN
admet-19	76	40	,	,	PUNCT
admet-19	76	41	surface	surface	NOUN
admet-19	76	42	area	area	NOUN
admet-19	76	43	and	and	CCONJ
admet-19	76	44	surface	surface	NOUN
admet-19	76	45	chemistry	chemistry	NOUN
admet-19	76	46	.	.	PUNCT
admet-19	77	1	4	4	X
admet-19	77	2	.	.	X
admet-19	77	3	nano	nano	NOUN
admet-19	77	4	-	-	PUNCT
admet-19	77	5	toxicology	toxicology	NOUN
admet-19	77	6	some	some	DET
admet-19	77	7	types	type	NOUN
admet-19	77	8	of	of	ADP
admet-19	77	9	nanomaterials	nanomaterial	NOUN
admet-19	77	10	may	may	AUX
admet-19	77	11	be	be	AUX
admet-19	77	12	harmful	harmful	ADJ
admet-19	77	13	to	to	ADP
admet-19	77	14	humans	human	NOUN
admet-19	77	15	.	.	PUNCT
admet-19	78	1	they	they	PRON
admet-19	78	2	can	can	AUX
admet-19	78	3	be	be	AUX
admet-19	78	4	classified	classify	VERB
admet-19	78	5	into	into	ADP
admet-19	78	6	the	the	DET
admet-19	78	7	following	follow	VERB
admet-19	78	8	two	two	NUM
admet-19	78	9	kinds	kind	NOUN
admet-19	78	10	of	of	ADP
admet-19	78	11	nanomaterial	nanomaterial	ADJ
admet-19	78	12	structure	structure	NOUN
admet-19	78	13	:	:	PUNCT
admet-19	78	14	1	1	X
admet-19	78	15	.	.	X
admet-19	78	16	free	free	ADJ
admet-19	78	17	form	form	NOUN
admet-19	78	18	nanoparticles	nanoparticle	NOUN
admet-19	78	19	:	:	PUNCT
admet-19	78	20	this	this	PRON
admet-19	78	21	refers	refer	VERB
admet-19	78	22	to	to	ADP
admet-19	78	23	the	the	DET
admet-19	78	24	direct	direct	ADJ
admet-19	78	25	use	use	NOUN
admet-19	78	26	of	of	ADP
admet-19	78	27	nanoparticles	nanoparticle	NOUN
admet-19	78	28	in	in	ADP
admet-19	78	29	the	the	DET
admet-19	78	30	manufacturing	manufacturing	NOUN
admet-19	78	31	process	process	NOUN
admet-19	78	32	.	.	PUNCT
admet-19	79	1	this	this	PRON
admet-19	79	2	usually	usually	ADV
admet-19	79	3	consists	consist	VERB
admet-19	79	4	of	of	ADP
admet-19	79	5	a	a	DET
admet-19	79	6	single	single	ADJ
admet-19	79	7	element	element	NOUN
admet-19	79	8	,	,	PUNCT
admet-19	79	9	compound	compound	NOUN
admet-19	79	10	or	or	CCONJ
admet-19	79	11	complex	complex	ADJ
admet-19	79	12	mixture	mixture	NOUN
admet-19	79	13	type	type	NOUN
admet-19	79	14	that	that	PRON
admet-19	79	15	can	can	AUX
admet-19	79	16	be	be	AUX
admet-19	79	17	released	release	VERB
admet-19	79	18	into	into	ADP
admet-19	79	19	water	water	NOUN
admet-19	79	20	and	and	CCONJ
admet-19	79	21	air	air	NOUN
admet-19	79	22	or	or	CCONJ
admet-19	79	23	accumulate	accumulate	VERB
admet-19	79	24	in	in	ADP
admet-19	79	25	soil	soil	NOUN
admet-19	79	26	.	.	PUNCT
admet-19	80	1	2	2	X
admet-19	80	2	.	.	NUM
admet-19	80	3	fixed	fix	VERB
admet-19	80	4	form	form	NOUN
admet-19	80	5	nanoparticles	nanoparticle	NOUN
admet-19	80	6	or	or	CCONJ
admet-19	80	7	nanocomposites	nanocomposite	NOUN
admet-19	80	8	:	:	PUNCT
admet-19	80	9	this	this	PRON
admet-19	80	10	refers	refer	VERB
admet-19	80	11	to	to	ADP
admet-19	80	12	a	a	DET
admet-19	80	13	nanomaterial	nanomaterial	NOUN
admet-19	80	14	that	that	PRON
admet-19	80	15	becomes	become	VERB
admet-19	80	16	part	part	NOUN
admet-19	80	17	of	of	ADP
admet-19	80	18	a	a	DET
admet-19	80	19	product	product	NOUN
admet-19	80	20	,	,	PUNCT
admet-19	80	21	which	which	PRON
admet-19	80	22	may	may	AUX
admet-19	80	23	be	be	AUX
admet-19	80	24	nanocomposites	nanocomposite	NOUN
admet-19	80	25	or	or	CCONJ
admet-19	80	26	nano	nano	NOUN
admet-19	80	27	surface	surface	NOUN
admet-19	80	28	structures	structure	NOUN
admet-19	80	29	.	.	PUNCT
admet-19	81	1	authors	author	NOUN
admet-19	81	2	admet	admet	PROPN
admet-19	81	3	&	&	CCONJ
admet-19	81	4	dmpk	dmpk	PROPN
admet-19	81	5	1(4	1(4	NUM
admet-19	81	6	)	)	PUNCT
admet-19	81	7	(	(	PUNCT
admet-19	81	8	2013	2013	NUM
admet-19	81	9	)	)	PUNCT
admet-19	81	10	76	76	NUM
admet-19	81	11	-	-	SYM
admet-19	81	12	81	81	NUM
admet-19	81	13	80	80	NUM
admet-19	81	14	compared	compare	VERB
admet-19	81	15	to	to	ADP
admet-19	81	16	fixed	fix	VERB
admet-19	81	17	nanoparticles	nanoparticle	NOUN
admet-19	81	18	,	,	PUNCT
admet-19	81	19	it	it	PRON
admet-19	81	20	is	be	AUX
admet-19	81	21	imperative	imperative	ADJ
admet-19	81	22	to	to	PART
admet-19	81	23	explore	explore	VERB
admet-19	81	24	the	the	DET
admet-19	81	25	possibility	possibility	NOUN
admet-19	81	26	that	that	SCONJ
admet-19	81	27	free	free	ADJ
admet-19	81	28	nanoparticles	nanoparticle	NOUN
admet-19	81	29	could	could	AUX
admet-19	81	30	be	be	AUX
admet-19	81	31	harmful	harmful	ADJ
admet-19	81	32	.	.	PUNCT
admet-19	82	1	since	since	SCONJ
admet-19	82	2	nanomaterials	nanomaterial	NOUN
admet-19	82	3	are	be	AUX
admet-19	82	4	quite	quite	ADV
admet-19	82	5	different	different	ADJ
admet-19	82	6	from	from	ADP
admet-19	82	7	the	the	DET
admet-19	82	8	original	original	ADJ
admet-19	82	9	material	material	NOUN
admet-19	82	10	,	,	PUNCT
admet-19	82	11	the	the	DET
admet-19	82	12	related	related	ADJ
admet-19	82	13	toxicity	toxicity	NOUN
admet-19	82	14	is	be	AUX
admet-19	82	15	expected	expect	VERB
admet-19	82	16	to	to	PART
admet-19	82	17	be	be	AUX
admet-19	82	18	unlike	unlike	ADP
admet-19	82	19	that	that	PRON
admet-19	82	20	of	of	ADP
admet-19	82	21	the	the	DET
admet-19	82	22	original	original	ADJ
admet-19	82	23	material	material	NOUN
admet-19	82	24	.	.	PUNCT
admet-19	83	1	generally	generally	ADV
admet-19	83	2	,	,	PUNCT
admet-19	83	3	it	it	PRON
admet-19	83	4	is	be	AUX
admet-19	83	5	difficult	difficult	ADJ
admet-19	83	6	to	to	PART
admet-19	83	7	obtain	obtain	VERB
admet-19	83	8	a	a	DET
admet-19	83	9	uniform	uniform	ADJ
admet-19	83	10	particle	particle	NOUN
admet-19	83	11	size	size	NOUN
admet-19	83	12	distribution	distribution	NOUN
admet-19	83	13	(	(	PUNCT
admet-19	83	14	monodisperse	monodisperse	NOUN
admet-19	83	15	)	)	PUNCT
admet-19	83	16	in	in	ADP
admet-19	83	17	a	a	DET
admet-19	83	18	nanoparticle	nanoparticle	NOUN
admet-19	83	19	formulation	formulation	NOUN
admet-19	83	20	.	.	PUNCT
admet-19	84	1	in	in	ADP
admet-19	84	2	the	the	DET
admet-19	84	3	absence	absence	NOUN
admet-19	84	4	of	of	ADP
admet-19	84	5	a	a	DET
admet-19	84	6	stabilizing	stabilize	VERB
admet-19	84	7	agent	agent	NOUN
admet-19	84	8	,	,	PUNCT
admet-19	84	9	nanoparticle	nanoparticle	NOUN
admet-19	84	10	aggregation	aggregation	NOUN
admet-19	84	11	is	be	AUX
admet-19	84	12	likely	likely	ADJ
admet-19	84	13	to	to	PART
admet-19	84	14	occur	occur	VERB
admet-19	84	15	,	,	PUNCT
admet-19	84	16	which	which	PRON
admet-19	84	17	could	could	AUX
admet-19	84	18	deteriorate	deteriorate	VERB
admet-19	84	19	the	the	DET
admet-19	84	20	properties	property	NOUN
admet-19	84	21	of	of	ADP
admet-19	84	22	the	the	DET
admet-19	84	23	product	product	NOUN
admet-19	84	24	and	and	CCONJ
admet-19	84	25	introduce	introduce	VERB
admet-19	84	26	complications	complication	NOUN
admet-19	84	27	in	in	ADP
admet-19	84	28	particle	particle	NOUN
admet-19	84	29	size	size	NOUN
admet-19	84	30	characterization	characterization	NOUN
admet-19	84	31	.	.	PUNCT
admet-19	85	1	some	some	DET
admet-19	85	2	nanomaterials	nanomaterial	NOUN
admet-19	85	3	,	,	PUNCT
admet-19	85	4	such	such	ADJ
admet-19	85	5	as	as	ADP
admet-19	85	6	carbon	carbon	NOUN
admet-19	85	7	nanotubes	nanotube	NOUN
admet-19	85	8	and	and	CCONJ
admet-19	85	9	metal	metal	NOUN
admet-19	85	10	oxides	oxide	NOUN
admet-19	85	11	,	,	PUNCT
admet-19	85	12	tend	tend	VERB
admet-19	85	13	to	to	PART
admet-19	85	14	form	form	VERB
admet-19	85	15	clusters	cluster	NOUN
admet-19	85	16	[	[	PUNCT
admet-19	85	17	10	10	NUM
admet-19	85	18	-	-	SYM
admet-19	85	19	11	11	NUM
admet-19	85	20	]	]	PUNCT
admet-19	85	21	.	.	PUNCT
admet-19	86	1	a	a	DET
admet-19	86	2	larger	large	ADJ
admet-19	86	3	particle	particle	NOUN
admet-19	86	4	size	size	NOUN
admet-19	86	5	could	could	AUX
admet-19	86	6	potentially	potentially	ADV
admet-19	86	7	reduce	reduce	VERB
admet-19	86	8	membrane	membrane	NOUN
admet-19	86	9	permeability	permeability	NOUN
admet-19	86	10	and	and	CCONJ
admet-19	86	11	discourage	discourage	VERB
admet-19	86	12	dispersion	dispersion	NOUN
admet-19	86	13	throughout	throughout	ADP
admet-19	86	14	the	the	DET
admet-19	86	15	human	human	ADJ
admet-19	86	16	body	body	NOUN
admet-19	86	17	,	,	PUNCT
admet-19	86	18	such	such	ADJ
admet-19	86	19	as	as	ADP
admet-19	86	20	in	in	ADP
admet-19	86	21	the	the	DET
admet-19	86	22	respiratory	respiratory	ADJ
admet-19	86	23	tract	tract	NOUN
admet-19	86	24	[	[	X
admet-19	86	25	1112	1112	NUM
admet-19	86	26	]	]	PUNCT
admet-19	86	27	.	.	PUNCT
admet-19	87	1	there	there	PRON
admet-19	87	2	are	be	VERB
admet-19	87	3	four	four	NUM
admet-19	87	4	ways	way	NOUN
admet-19	87	5	that	that	PRON
admet-19	87	6	nanoparticles	nanoparticle	NOUN
admet-19	87	7	can	can	AUX
admet-19	87	8	enter	enter	VERB
admet-19	87	9	the	the	DET
admet-19	87	10	human	human	ADJ
admet-19	87	11	body	body	NOUN
admet-19	87	12	:	:	PUNCT
admet-19	87	13	through	through	ADP
admet-19	87	14	the	the	DET
admet-19	87	15	skin	skin	NOUN
admet-19	87	16	,	,	PUNCT
admet-19	87	17	by	by	ADP
admet-19	87	18	inhalation	inhalation	NOUN
admet-19	87	19	,	,	PUNCT
admet-19	87	20	oral	oral	ADJ
admet-19	87	21	ingestion	ingestion	NOUN
admet-19	87	22	or	or	CCONJ
admet-19	87	23	during	during	ADP
admet-19	87	24	a	a	DET
admet-19	87	25	medical	medical	ADJ
admet-19	87	26	procedure	procedure	NOUN
admet-19	87	27	(	(	PUNCT
admet-19	87	28	e.g.	e.g.	ADV
admet-19	87	29	release	release	NOUN
admet-19	87	30	from	from	ADP
admet-19	87	31	implants	implant	NOUN
admet-19	87	32	)	)	PUNCT
admet-19	87	33	.	.	PUNCT
admet-19	88	1	exposure	exposure	NOUN
admet-19	88	2	assessments	assessment	NOUN
admet-19	88	3	are	be	AUX
admet-19	88	4	used	use	VERB
admet-19	88	5	to	to	PART
admet-19	88	6	evaluate	evaluate	VERB
admet-19	88	7	the	the	DET
admet-19	88	8	risk	risk	NOUN
admet-19	88	9	of	of	ADP
admet-19	88	10	human	human	NOUN
admet-19	88	11	in	in	ADP
admet-19	88	12	contact	contact	NOUN
admet-19	88	13	with	with	ADP
admet-19	88	14	the	the	DET
admet-19	88	15	nanoparticle	nanoparticle	NOUN
admet-19	88	16	product	product	NOUN
admet-19	88	17	.	.	PUNCT
admet-19	89	1	this	this	PRON
admet-19	89	2	should	should	AUX
admet-19	89	3	include	include	VERB
admet-19	89	4	the	the	DET
admet-19	89	5	whole	whole	ADJ
admet-19	89	6	life	life	NOUN
admet-19	89	7	cycle	cycle	NOUN
admet-19	89	8	of	of	ADP
admet-19	89	9	the	the	DET
admet-19	89	10	product	product	NOUN
admet-19	89	11	starting	start	VERB
admet-19	89	12	from	from	ADP
admet-19	89	13	synthesis	synthesis	NOUN
admet-19	89	14	to	to	ADP
admet-19	89	15	disposal	disposal	NOUN
admet-19	89	16	.	.	PUNCT
admet-19	90	1	although	although	SCONJ
admet-19	90	2	the	the	DET
admet-19	90	3	main	main	ADJ
admet-19	90	4	concerns	concern	NOUN
admet-19	90	5	are	be	AUX
admet-19	90	6	the	the	DET
admet-19	90	7	hazard	hazard	NOUN
admet-19	90	8	to	to	ADP
admet-19	90	9	the	the	DET
admet-19	90	10	customer	customer	NOUN
admet-19	90	11	during	during	ADP
admet-19	90	12	product	product	NOUN
admet-19	90	13	usage	usage	NOUN
admet-19	90	14	,	,	PUNCT
admet-19	90	15	assessments	assessment	NOUN
admet-19	90	16	should	should	AUX
admet-19	90	17	also	also	ADV
admet-19	90	18	be	be	AUX
admet-19	90	19	done	do	VERB
admet-19	90	20	after	after	ADP
admet-19	90	21	disposal	disposal	NOUN
admet-19	90	22	to	to	PART
admet-19	90	23	evaluate	evaluate	VERB
admet-19	90	24	nanoparticle	nanoparticle	NOUN
admet-19	90	25	release	release	NOUN
admet-19	90	26	into	into	ADP
admet-19	90	27	the	the	DET
admet-19	90	28	environment	environment	NOUN
admet-19	90	29	.	.	PUNCT
admet-19	91	1	furthermore	furthermore	ADV
admet-19	91	2	,	,	PUNCT
admet-19	91	3	the	the	DET
admet-19	91	4	manufacturing	manufacturing	NOUN
admet-19	91	5	staff	staff	NOUN
admet-19	91	6	remains	remain	VERB
admet-19	91	7	the	the	DET
admet-19	91	8	most	most	ADV
admet-19	91	9	likely	likely	ADJ
admet-19	91	10	population	population	NOUN
admet-19	91	11	to	to	PART
admet-19	91	12	be	be	AUX
admet-19	91	13	exposed	expose	VERB
admet-19	91	14	to	to	ADP
admet-19	91	15	nanoparticles	nanoparticle	NOUN
admet-19	91	16	,	,	PUNCT
admet-19	91	17	and	and	CCONJ
admet-19	91	18	should	should	AUX
admet-19	91	19	be	be	AUX
admet-19	91	20	properly	properly	ADV
admet-19	91	21	evaluated	evaluate	VERB
admet-19	91	22	during	during	ADP
admet-19	91	23	risk	risk	NOUN
admet-19	91	24	management	management	NOUN
admet-19	91	25	.	.	PUNCT
admet-19	92	1	the	the	DET
admet-19	92	2	nanoparticle	nanoparticle	NOUN
admet-19	92	3	exposure	exposure	NOUN
admet-19	92	4	assessment	assessment	NOUN
admet-19	92	5	could	could	AUX
admet-19	92	6	vary	vary	VERB
admet-19	92	7	between	between	ADP
admet-19	92	8	different	different	ADJ
admet-19	92	9	products	product	NOUN
admet-19	92	10	,	,	PUNCT
admet-19	92	11	and	and	CCONJ
admet-19	92	12	should	should	AUX
admet-19	92	13	depend	depend	VERB
admet-19	92	14	on	on	ADP
admet-19	92	15	the	the	DET
admet-19	92	16	product	product	NOUN
admet-19	92	17	design	design	NOUN
admet-19	92	18	to	to	PART
admet-19	92	19	assess	assess	VERB
admet-19	92	20	any	any	DET
admet-19	92	21	potential	potential	ADJ
admet-19	92	22	risks	risk	NOUN
admet-19	92	23	.	.	PUNCT
admet-19	93	1	the	the	DET
admet-19	93	2	dimensions	dimension	NOUN
admet-19	93	3	of	of	ADP
admet-19	93	4	the	the	DET
admet-19	93	5	nanomaterial	nanomaterial	NOUN
admet-19	93	6	affect	affect	VERB
admet-19	93	7	its	its	PRON
admet-19	93	8	toxicity	toxicity	NOUN
admet-19	93	9	.	.	PUNCT
admet-19	94	1	for	for	ADP
admet-19	94	2	nanoparticles	nanoparticle	NOUN
admet-19	94	3	,	,	PUNCT
admet-19	94	4	smaller	small	ADJ
admet-19	94	5	particles	particle	NOUN
admet-19	94	6	are	be	AUX
admet-19	94	7	usually	usually	ADV
admet-19	94	8	more	more	ADV
admet-19	94	9	active	active	ADJ
admet-19	94	10	and	and	CCONJ
admet-19	94	11	potentially	potentially	ADV
admet-19	94	12	more	more	ADV
admet-19	94	13	toxic	toxic	ADJ
admet-19	94	14	.	.	PUNCT
admet-19	95	1	moreover	moreover	ADV
admet-19	95	2	,	,	PUNCT
admet-19	95	3	one	one	PRON
admet-19	95	4	should	should	AUX
admet-19	95	5	take	take	VERB
admet-19	95	6	into	into	ADP
admet-19	95	7	account	account	NOUN
admet-19	95	8	the	the	DET
admet-19	95	9	shape	shape	NOUN
admet-19	95	10	factor	factor	NOUN
admet-19	95	11	.	.	PUNCT
admet-19	96	1	the	the	DET
admet-19	96	2	human	human	ADJ
admet-19	96	3	immune	immune	ADJ
admet-19	96	4	system	system	NOUN
admet-19	96	5	is	be	AUX
admet-19	96	6	poorly	poorly	ADV
admet-19	96	7	defensive	defensive	ADJ
admet-19	96	8	against	against	ADP
admet-19	96	9	nanoparticles	nanoparticle	NOUN
admet-19	96	10	,	,	PUNCT
admet-19	96	11	and	and	CCONJ
admet-19	96	12	does	do	AUX
admet-19	96	13	not	not	PART
admet-19	96	14	recognize	recognize	VERB
admet-19	96	15	nanoparticles	nanoparticle	NOUN
admet-19	96	16	.	.	PUNCT
admet-19	97	1	for	for	ADP
admet-19	97	2	instance	instance	NOUN
admet-19	97	3	,	,	PUNCT
admet-19	97	4	the	the	DET
admet-19	97	5	defense	defense	NOUN
admet-19	97	6	mechanism	mechanism	NOUN
admet-19	97	7	in	in	ADP
admet-19	97	8	the	the	DET
admet-19	97	9	lung	lung	NOUN
admet-19	97	10	can	can	AUX
admet-19	97	11	not	not	PART
admet-19	97	12	deal	deal	VERB
admet-19	97	13	with	with	ADP
admet-19	97	14	nanoparticles	nanoparticle	NOUN
admet-19	97	15	less	less	ADJ
admet-19	97	16	than	than	ADP
admet-19	97	17	70	70	NUM
admet-19	97	18	nm	nm	NOUN
admet-19	97	19	in	in	ADP
admet-19	97	20	size	size	NOUN
admet-19	97	21	[	[	X
admet-19	97	22	6,13	6,13	NUM
admet-19	97	23	]	]	PUNCT
admet-19	97	24	.	.	PUNCT
admet-19	98	1	nanoparticles	nanoparticle	NOUN
admet-19	98	2	less	less	ADJ
admet-19	98	3	than	than	ADP
admet-19	98	4	50	50	NUM
admet-19	98	5	nm	nm	NOUN
admet-19	98	6	in	in	ADP
admet-19	98	7	size	size	NOUN
admet-19	98	8	can	can	AUX
admet-19	98	9	easily	easily	ADV
admet-19	98	10	enter	enter	VERB
admet-19	98	11	and	and	CCONJ
admet-19	98	12	move	move	VERB
admet-19	98	13	into	into	ADP
admet-19	98	14	the	the	DET
admet-19	98	15	nucleus	nucleus	NOUN
admet-19	98	16	of	of	ADP
admet-19	98	17	human	human	ADJ
admet-19	98	18	cells	cell	NOUN
admet-19	98	19	,	,	PUNCT
admet-19	98	20	and	and	CCONJ
admet-19	98	21	30	30	NUM
admet-19	98	22	nm	nm	ADJ
admet-19	98	23	particles	particle	NOUN
admet-19	98	24	may	may	AUX
admet-19	98	25	damage	damage	VERB
admet-19	98	26	the	the	DET
admet-19	98	27	central	central	ADJ
admet-19	98	28	nervous	nervous	ADJ
admet-19	98	29	system	system	NOUN
admet-19	98	30	[	[	X
admet-19	98	31	6,13	6,13	NUM
admet-19	98	32	]	]	PUNCT
admet-19	98	33	.	.	PUNCT
admet-19	99	1	it	it	PRON
admet-19	99	2	is	be	AUX
admet-19	99	3	evident	evident	ADJ
admet-19	99	4	that	that	SCONJ
admet-19	99	5	nanomaterial	nanomaterial	ADJ
admet-19	99	6	research	research	NOUN
admet-19	99	7	and	and	CCONJ
admet-19	99	8	risk	risk	NOUN
admet-19	99	9	assessments	assessment	NOUN
admet-19	99	10	are	be	AUX
admet-19	99	11	urgently	urgently	ADV
admet-19	99	12	needed	need	VERB
admet-19	99	13	to	to	PART
admet-19	99	14	clarify	clarify	VERB
admet-19	99	15	the	the	DET
admet-19	99	16	potential	potential	ADJ
admet-19	99	17	effects	effect	NOUN
admet-19	99	18	of	of	ADP
admet-19	99	19	these	these	DET
admet-19	99	20	materials	material	NOUN
admet-19	99	21	on	on	ADP
admet-19	99	22	humans	human	NOUN
admet-19	99	23	,	,	PUNCT
admet-19	99	24	particularly	particularly	ADV
admet-19	99	25	in	in	ADP
admet-19	99	26	terms	term	NOUN
admet-19	99	27	of	of	ADP
admet-19	99	28	cardiovascular	cardiovascular	ADJ
admet-19	99	29	,	,	PUNCT
admet-19	99	30	carcinogenic	carcinogenic	ADJ
admet-19	99	31	,	,	PUNCT
admet-19	99	32	reproductive	reproductive	ADJ
admet-19	99	33	,	,	PUNCT
admet-19	99	34	developmental	developmental	ADJ
admet-19	99	35	,	,	PUNCT
admet-19	99	36	immunological	immunological	ADJ
admet-19	99	37	and	and	CCONJ
admet-19	99	38	neurological	neurological	ADJ
admet-19	99	39	aspects	aspect	NOUN
admet-19	99	40	.	.	PUNCT
admet-19	100	1	although	although	SCONJ
admet-19	100	2	there	there	PRON
admet-19	100	3	are	be	VERB
admet-19	100	4	still	still	ADV
admet-19	100	5	many	many	ADJ
admet-19	100	6	uncertainties	uncertainty	NOUN
admet-19	100	7	and	and	CCONJ
admet-19	100	8	limitations	limitation	NOUN
admet-19	100	9	in	in	ADP
admet-19	100	10	the	the	DET
admet-19	100	11	current	current	ADJ
admet-19	100	12	understanding	understanding	NOUN
admet-19	100	13	of	of	ADP
admet-19	100	14	nanomaterials	nanomaterial	NOUN
admet-19	100	15	,	,	PUNCT
admet-19	100	16	it	it	PRON
admet-19	100	17	is	be	AUX
admet-19	100	18	essential	essential	ADJ
admet-19	100	19	to	to	PART
admet-19	100	20	conduct	conduct	VERB
admet-19	100	21	risk	risk	NOUN
admet-19	100	22	assessments	assessment	NOUN
admet-19	100	23	on	on	ADP
admet-19	100	24	nanomaterials	nanomaterial	NOUN
admet-19	100	25	and	and	CCONJ
admet-19	100	26	nano	nano	NOUN
admet-19	100	27	medical	medical	ADJ
admet-19	100	28	devices	device	NOUN
admet-19	100	29	before	before	SCONJ
admet-19	100	30	the	the	DET
admet-19	100	31	product	product	NOUN
admet-19	100	32	is	be	AUX
admet-19	100	33	allowed	allow	VERB
admet-19	100	34	to	to	PART
admet-19	100	35	be	be	AUX
admet-19	100	36	marketed	market	VERB
admet-19	100	37	.	.	PUNCT
admet-19	101	1	5	5	X
admet-19	101	2	.	.	X
admet-19	101	3	conclusions	conclusion	NOUN
admet-19	101	4	in	in	ADP
admet-19	101	5	view	view	NOUN
admet-19	101	6	of	of	ADP
admet-19	101	7	rapid	rapid	ADJ
admet-19	101	8	advancements	advancement	NOUN
admet-19	101	9	in	in	ADP
admet-19	101	10	the	the	DET
admet-19	101	11	field	field	NOUN
admet-19	101	12	of	of	ADP
admet-19	101	13	nanotechnology	nanotechnology	NOUN
admet-19	101	14	,	,	PUNCT
admet-19	101	15	it	it	PRON
admet-19	101	16	is	be	AUX
admet-19	101	17	very	very	ADV
admet-19	101	18	challenging	challenging	ADJ
admet-19	101	19	to	to	PART
admet-19	101	20	come	come	VERB
admet-19	101	21	up	up	ADP
admet-19	101	22	with	with	ADP
admet-19	101	23	a	a	DET
admet-19	101	24	set	set	NOUN
admet-19	101	25	of	of	ADP
admet-19	101	26	nano	nano	NOUN
admet-19	101	27	medical	medical	ADJ
admet-19	101	28	device	device	NOUN
admet-19	101	29	regulations	regulation	NOUN
admet-19	101	30	that	that	PRON
admet-19	101	31	can	can	AUX
admet-19	101	32	cover	cover	VERB
admet-19	101	33	all	all	DET
admet-19	101	34	the	the	DET
admet-19	101	35	relevant	relevant	ADJ
admet-19	101	36	issues	issue	NOUN
admet-19	101	37	.	.	PUNCT
admet-19	102	1	for	for	ADP
admet-19	102	2	currently	currently	ADV
admet-19	102	3	listed	list	VERB
admet-19	102	4	nano	nano	ADJ
admet-19	102	5	medical	medical	ADJ
admet-19	102	6	products	product	NOUN
admet-19	102	7	,	,	PUNCT
admet-19	102	8	such	such	ADJ
admet-19	102	9	as	as	ADP
admet-19	102	10	those	those	PRON
admet-19	102	11	containing	contain	VERB
admet-19	102	12	nano	nano	NOUN
admet-19	102	13	silver	silver	ADJ
admet-19	102	14	antimicrobial	antimicrobial	ADJ
admet-19	102	15	dressings	dressing	NOUN
admet-19	102	16	,	,	PUNCT
admet-19	102	17	the	the	DET
admet-19	102	18	fda	fda	PROPN
admet-19	102	19	review	review	NOUN
admet-19	102	20	process	process	NOUN
admet-19	102	21	has	have	AUX
admet-19	102	22	been	be	AUX
admet-19	102	23	completed	complete	VERB
admet-19	102	24	.	.	PUNCT
admet-19	103	1	this	this	PRON
admet-19	103	2	will	will	AUX
admet-19	103	3	serve	serve	VERB
admet-19	103	4	as	as	ADP
admet-19	103	5	a	a	DET
admet-19	103	6	classic	classic	ADJ
admet-19	103	7	example	example	NOUN
admet-19	103	8	for	for	ADP
admet-19	103	9	the	the	DET
admet-19	103	10	regulatory	regulatory	ADJ
admet-19	103	11	regulations	regulation	NOUN
admet-19	103	12	on	on	ADP
admet-19	103	13	a	a	DET
admet-19	103	14	nano	nano	ADJ
admet-19	103	15	medical	medical	ADJ
admet-19	103	16	device	device	NOUN
admet-19	103	17	.	.	PUNCT
admet-19	104	1	however	however	ADV
admet-19	104	2	,	,	PUNCT
admet-19	104	3	it	it	PRON
admet-19	104	4	is	be	AUX
admet-19	104	5	questionable	questionable	ADJ
admet-19	104	6	whether	whether	SCONJ
admet-19	104	7	such	such	DET
admet-19	104	8	an	an	DET
admet-19	104	9	example	example	NOUN
admet-19	104	10	can	can	AUX
admet-19	104	11	be	be	AUX
admet-19	104	12	directly	directly	ADV
admet-19	104	13	extended	extend	VERB
admet-19	104	14	to	to	ADP
admet-19	104	15	other	other	ADJ
admet-19	104	16	kinds	kind	NOUN
admet-19	104	17	of	of	ADP
admet-19	104	18	nano	nano	NOUN
admet-19	104	19	medical	medical	ADJ
admet-19	104	20	devices	device	NOUN
admet-19	104	21	because	because	SCONJ
admet-19	104	22	the	the	DET
admet-19	104	23	risk	risk	NOUN
admet-19	104	24	and	and	CCONJ
admet-19	104	25	benefit	benefit	NOUN
admet-19	104	26	factors	factor	NOUN
admet-19	104	27	are	be	AUX
admet-19	104	28	likely	likely	ADJ
admet-19	104	29	to	to	PART
admet-19	104	30	be	be	AUX
admet-19	104	31	very	very	ADV
admet-19	104	32	different	different	ADJ
admet-19	104	33	.	.	PUNCT
admet-19	105	1	for	for	ADP
admet-19	105	2	instance	instance	NOUN
admet-19	105	3	,	,	PUNCT
admet-19	105	4	nanoparticle	nanoparticle	NOUN
admet-19	105	5	drug	drug	NOUN
admet-19	105	6	delivery	delivery	NOUN
admet-19	105	7	systems	system	NOUN
admet-19	105	8	that	that	PRON
admet-19	105	9	work	work	VERB
admet-19	105	10	by	by	ADP
admet-19	105	11	targeting	target	VERB
admet-19	105	12	tumors	tumor	NOUN
admet-19	105	13	and	and	CCONJ
admet-19	105	14	nano	nano	NOUN
admet-19	105	15	silver	silver	ADJ
admet-19	105	16	antimicrobial	antimicrobial	ADJ
admet-19	105	17	dressing	dressing	NOUN
admet-19	105	18	products	product	NOUN
admet-19	105	19	are	be	AUX
admet-19	105	20	based	base	VERB
admet-19	105	21	on	on	ADP
admet-19	105	22	completely	completely	ADV
admet-19	105	23	different	different	ADJ
admet-19	105	24	scientific	scientific	ADJ
admet-19	105	25	principles	principle	NOUN
admet-19	105	26	.	.	PUNCT
admet-19	106	1	nevertheless	nevertheless	ADV
admet-19	106	2	,	,	PUNCT
admet-19	106	3	it	it	PRON
admet-19	106	4	is	be	AUX
admet-19	106	5	mandatory	mandatory	ADJ
admet-19	106	6	for	for	SCONJ
admet-19	106	7	the	the	DET
admet-19	106	8	manufacture	manufacture	NOUN
admet-19	106	9	of	of	ADP
admet-19	106	10	nano	nano	NOUN
admet-19	106	11	medical	medical	ADJ
admet-19	106	12	devices	device	NOUN
admet-19	106	13	to	to	PART
admet-19	106	14	meet	meet	VERB
admet-19	106	15	quality	quality	NOUN
admet-19	106	16	,	,	PUNCT
admet-19	106	17	testing	testing	NOUN
admet-19	106	18	and	and	CCONJ
admet-19	106	19	safety	safety	NOUN
admet-19	106	20	and	and	CCONJ
admet-19	106	21	other	other	ADJ
admet-19	106	22	regulations	regulation	NOUN
admet-19	106	23	in	in	ADP
admet-19	106	24	order	order	NOUN
admet-19	106	25	to	to	PART
admet-19	106	26	protect	protect	VERB
admet-19	106	27	the	the	DET
admet-19	106	28	manufacturing	manufacturing	NOUN
admet-19	106	29	staff	staff	NOUN
admet-19	106	30	,	,	PUNCT
admet-19	106	31	customers	customer	NOUN
admet-19	106	32	and	and	CCONJ
admet-19	106	33	end	end	VERB
admet-19	106	34	users	user	NOUN
admet-19	106	35	.	.	PUNCT
admet-19	107	1	equally	equally	ADV
admet-19	107	2	important	important	ADJ
admet-19	107	3	,	,	PUNCT
admet-19	107	4	device	device	NOUN
admet-19	107	5	manufacturers	manufacturer	NOUN
admet-19	107	6	are	be	AUX
admet-19	107	7	also	also	ADV
admet-19	107	8	required	require	VERB
admet-19	107	9	to	to	PART
admet-19	107	10	submit	submit	VERB
admet-19	107	11	product	product	NOUN
admet-19	107	12	development	development	NOUN
admet-19	107	13	,	,	PUNCT
admet-19	107	14	testing	testing	NOUN
admet-19	107	15	and	and	CCONJ
admet-19	107	16	registration	registration	NOUN
admet-19	107	17	applications	application	NOUN
admet-19	107	18	with	with	ADP
admet-19	107	19	other	other	ADJ
admet-19	107	20	related	related	ADJ
admet-19	107	21	information	information	NOUN
admet-19	107	22	to	to	ADP
admet-19	107	23	the	the	DET
admet-19	107	24	relevant	relevant	ADJ
admet-19	107	25	regulatory	regulatory	ADJ
admet-19	107	26	body	body	NOUN
admet-19	107	27	for	for	ADP
admet-19	107	28	proper	proper	ADJ
admet-19	107	29	evaluation	evaluation	NOUN
admet-19	107	30	.	.	PUNCT
admet-19	108	1	because	because	SCONJ
admet-19	108	2	of	of	ADP
admet-19	108	3	the	the	DET
admet-19	108	4	diversity	diversity	NOUN
admet-19	108	5	of	of	ADP
admet-19	108	6	admet	admet	PROPN
admet-19	108	7	&	&	CCONJ
admet-19	108	8	dmpk	dmpk	PROPN
admet-19	108	9	1(4	1(4	NUM
admet-19	108	10	)	)	PUNCT
admet-19	108	11	(	(	PUNCT
admet-19	108	12	2013	2013	NUM
admet-19	108	13	)	)	PUNCT
admet-19	108	14	76	76	NUM
admet-19	108	15	-	-	SYM
admet-19	108	16	81	81	NUM
admet-19	108	17	nanomaterials	nanomaterial	NOUN
admet-19	108	18	safety	safety	NOUN
admet-19	108	19	doi	doi	NOUN
admet-19	108	20	:	:	PUNCT
admet-19	108	21	10.5599	10.5599	NUM
admet-19	108	22	/	/	SYM
admet-19	108	23	admet.1.4.19	admet.1.4.19	NOUN
admet-19	108	24	81	81	NUM
admet-19	108	25	nanomaterials	nanomaterial	NOUN
admet-19	108	26	that	that	PRON
admet-19	108	27	can	can	AUX
admet-19	108	28	be	be	AUX
admet-19	108	29	applied	apply	VERB
admet-19	108	30	to	to	ADP
admet-19	108	31	medical	medical	ADJ
admet-19	108	32	devices	device	NOUN
admet-19	108	33	,	,	PUNCT
admet-19	108	34	regulatory	regulatory	ADJ
admet-19	108	35	regulations	regulation	NOUN
admet-19	108	36	are	be	AUX
admet-19	108	37	important	important	ADJ
admet-19	108	38	,	,	PUNCT
admet-19	108	39	and	and	CCONJ
admet-19	108	40	frequent	frequent	ADJ
admet-19	108	41	updates	update	NOUN
admet-19	108	42	are	be	AUX
admet-19	108	43	needed	need	VERB
admet-19	108	44	to	to	PART
admet-19	108	45	keep	keep	VERB
admet-19	108	46	pace	pace	NOUN
admet-19	108	47	with	with	ADP
admet-19	108	48	rapidly	rapidly	ADV
admet-19	108	49	emerging	emerge	VERB
admet-19	108	50	applications	application	NOUN
admet-19	108	51	.	.	PUNCT
admet-19	109	1	acknowledgments	acknowledgment	NOUN
admet-19	109	2	the	the	DET
admet-19	109	3	office	office	NOUN
admet-19	109	4	of	of	ADP
admet-19	109	5	medical	medical	ADJ
admet-19	109	6	device	device	NOUN
admet-19	109	7	evaluation	evaluation	NOUN
admet-19	109	8	(	(	PUNCT
admet-19	109	9	omde	omde	PROPN
admet-19	109	10	)	)	PUNCT
admet-19	109	11	would	would	AUX
admet-19	109	12	like	like	VERB
admet-19	109	13	to	to	PART
admet-19	109	14	acknowledge	acknowledge	VERB
admet-19	109	15	the	the	DET
admet-19	109	16	support	support	NOUN
admet-19	109	17	of	of	ADP
admet-19	109	18	the	the	DET
admet-19	109	19	food	food	NOUN
admet-19	109	20	and	and	CCONJ
admet-19	109	21	drug	drug	PROPN
admet-19	109	22	administration	administration	NOUN
admet-19	109	23	of	of	ADP
admet-19	109	24	taiwan	taiwan	PROPN
admet-19	109	25	and	and	CCONJ
admet-19	109	26	the	the	DET
admet-19	109	27	center	center	NOUN
admet-19	109	28	for	for	ADP
admet-19	109	29	measurement	measurement	NOUN
admet-19	109	30	standards	standard	NOUN
admet-19	109	31	of	of	ADP
admet-19	109	32	itri	itri	ADJ
admet-19	109	33	towards	towards	ADP
admet-19	109	34	omde	omde	NOUN
admet-19	109	35	’s	’s	PART
admet-19	109	36	work	work	NOUN
admet-19	109	37	in	in	ADP
admet-19	109	38	nano	nano	NOUN
admet-19	109	39	medical	medical	ADJ
admet-19	109	40	device	device	NOUN
admet-19	109	41	risk	risk	NOUN
admet-19	109	42	assessment	assessment	NOUN
admet-19	109	43	,	,	PUNCT
admet-19	109	44	and	and	CCONJ
admet-19	109	45	all	all	DET
admet-19	109	46	our	our	PRON
admet-19	109	47	team	team	NOUN
admet-19	109	48	members	member	NOUN
admet-19	109	49	who	who	PRON
admet-19	109	50	made	make	VERB
admet-19	109	51	this	this	DET
admet-19	109	52	work	work	NOUN
admet-19	109	53	feasible	feasible	ADJ
admet-19	109	54	.	.	PUNCT
admet-19	110	1	references	reference	NOUN
admet-19	110	2	[	[	X
admet-19	110	3	1	1	NUM
admet-19	110	4	]	]	X
admet-19	110	5	fda	fda	PROPN
admet-19	110	6	:	:	PUNCT
admet-19	110	7	considering	consider	VERB
admet-19	110	8	whether	whether	SCONJ
admet-19	110	9	an	an	DET
admet-19	110	10	fda	fda	PROPN
admet-19	110	11	-	-	PUNCT
admet-19	110	12	regulated	regulate	VERB
admet-19	110	13	product	product	NOUN
admet-19	110	14	involves	involve	VERB
admet-19	110	15	the	the	DET
admet-19	110	16	application	application	NOUN
admet-19	110	17	of	of	ADP
admet-19	110	18	nanotechnology	nanotechnology	NOUN
admet-19	110	19	,	,	PUNCT
admet-19	110	20	http://www.fda.gov/regulatoryinformation/guidances/ucm257698.htm	http://www.fda.gov/regulatoryinformation/guidances/ucm257698.htm	PROPN
admet-19	110	21	(	(	PUNCT
admet-19	110	22	accessed	access	VERB
admet-19	110	23	12	12	NUM
admet-19	110	24	nd	nd	NUM
admet-19	110	25	nov	nov	PROPN
admet-19	110	26	2013	2013	NUM
admet-19	110	27	)	)	PUNCT
admet-19	111	1	[	[	X
admet-19	111	2	2	2	X
admet-19	111	3	]	]	X
admet-19	111	4	j	j	PROPN
admet-19	111	5	miller	miller	PROPN
admet-19	111	6	,	,	PUNCT
admet-19	111	7	the	the	DET
admet-19	111	8	columbia	columbia	PROPN
admet-19	111	9	science	science	PROPN
admet-19	111	10	and	and	CCONJ
admet-19	111	11	technology	technology	NOUN
admet-19	111	12	law	law	NOUN
admet-19	111	13	review	review	VERB
admet-19	111	14	4	4	NUM
admet-19	111	15	(	(	PUNCT
admet-19	111	16	2003	2003	NUM
admet-19	111	17	)	)	PUNCT
admet-19	111	18	article	article	NOUN
admet-19	111	19	5	5	NUM
admet-19	111	20	.	.	PUNCT
admet-19	111	21	http://www.stlr.org/cite.cgi?volume=4&article=5	http://www.stlr.org/cite.cgi?volume=4&article=5	NOUN
admet-19	111	22	(	(	PUNCT
admet-19	111	23	accessed	access	VERB
admet-19	111	24	12	12	NUM
admet-19	111	25	nd	nd	NUM
admet-19	111	26	nov	nov	PROPN
admet-19	111	27	2013	2013	NUM
admet-19	111	28	)	)	PUNCT
admet-19	112	1	[	[	X
admet-19	112	2	3	3	X
admet-19	112	3	]	]	X
admet-19	112	4	fda	fda	PROPN
admet-19	112	5	:	:	PUNCT
admet-19	112	6	nanotechnology	nanotechnology	NOUN
admet-19	112	7	,	,	PUNCT
admet-19	112	8	http://www.fda.gov/scienceresearch/specialtopics/nanotechnology/default.htm	http://www.fda.gov/scienceresearch/specialtopics/nanotechnology/default.htm	X
admet-19	112	9	(	(	PUNCT
admet-19	112	10	accessed	access	VERB
admet-19	112	11	12	12	NUM
admet-19	112	12	nd	nd	NUM
admet-19	112	13	nov	nov	PROPN
admet-19	112	14	2013	2013	NUM
admet-19	112	15	)	)	PUNCT
admet-19	113	1	[	[	X
admet-19	113	2	4	4	X
admet-19	113	3	]	]	PUNCT
admet-19	113	4	nanotechnology	nanotechnology	NOUN
admet-19	113	5	.	.	PUNCT
admet-19	114	1	a	a	DET
admet-19	114	2	report	report	NOUN
admet-19	114	3	of	of	ADP
admet-19	114	4	the	the	DET
admet-19	114	5	u.s	u.s	PROPN
admet-19	114	6	.	.	PROPN
admet-19	114	7	food	food	PROPN
admet-19	114	8	and	and	CCONJ
admet-19	114	9	drug	drug	PROPN
admet-19	114	10	administration	administration	PROPN
admet-19	114	11	nanotechnology	nanotechnology	PROPN
admet-19	114	12	task	task	PROPN
admet-19	114	13	force	force	PROPN
admet-19	114	14	,	,	PUNCT
admet-19	114	15	july	july	PROPN
admet-19	114	16	25	25	NUM
admet-19	114	17	,	,	PUNCT
admet-19	114	18	2007	2007	NUM
admet-19	114	19	.	.	PUNCT
admet-19	115	1	[	[	X
admet-19	115	2	5	5	NUM
admet-19	115	3	]	]	SYM
admet-19	115	4	nanotehnology	nanotehnology	NOUN
admet-19	115	5	&	&	CCONJ
admet-19	115	6	fda	fda	PROPN
admet-19	115	7	-	-	PUNCT
admet-19	115	8	regulated	regulate	VERB
admet-19	115	9	products	product	NOUN
admet-19	115	10	:	:	PUNCT
admet-19	115	11	the	the	DET
admet-19	115	12	essential	essential	ADJ
admet-19	115	13	guide	guide	NOUN
admet-19	115	14	,	,	PUNCT
admet-19	115	15	the	the	DET
admet-19	115	16	food	food	NOUN
admet-19	115	17	and	and	CCONJ
admet-19	115	18	drug	drug	NOUN
admet-19	115	19	law	law	PROPN
admet-19	115	20	institute	institute	NOUN
admet-19	115	21	.	.	PUNCT
admet-19	116	1	2009	2009	NUM
admet-19	116	2	.	.	PUNCT
admet-19	117	1	[	[	X
admet-19	117	2	6	6	NUM
admet-19	117	3	]	]	X
admet-19	117	4	j.s	j.s	PROPN
admet-19	117	5	.	.	PROPN
admet-19	117	6	tsuji	tsuji	PROPN
admet-19	117	7	,	,	PUNCT
admet-19	117	8	a.d	a.d	PROPN
admet-19	117	9	.	.	PROPN
admet-19	117	10	maynard	maynard	PROPN
admet-19	117	11	,	,	PUNCT
admet-19	117	12	p.c	p.c	PROPN
admet-19	117	13	.	.	PROPN
admet-19	117	14	howard	howard	PROPN
admet-19	117	15	,	,	PUNCT
admet-19	117	16	j.t	j.t	PROPN
admet-19	117	17	.	.	PROPN
admet-19	117	18	james	james	PROPN
admet-19	117	19	,	,	PUNCT
admet-19	117	20	c.w	c.w	PROPN
admet-19	117	21	.	.	PROPN
admet-19	117	22	lam	lam	PROPN
admet-19	117	23	,	,	PUNCT
admet-19	117	24	d.b	d.b	PROPN
admet-19	117	25	.	.	PROPN
admet-19	117	26	warheit	warheit	PROPN
admet-19	117	27	,	,	PUNCT
admet-19	117	28	a.b	a.b	PROPN
admet-19	117	29	.	.	PROPN
admet-19	117	30	santamaria	santamaria	PROPN
admet-19	117	31	,	,	PUNCT
admet-19	117	32	toxicology	toxicology	NOUN
admet-19	117	33	sciences	science	NOUN
admet-19	117	34	89	89	NUM
admet-19	117	35	(	(	PUNCT
admet-19	117	36	2006	2006	NUM
admet-19	117	37	)	)	PUNCT
admet-19	117	38	42	42	NUM
admet-19	117	39	-	-	SYM
admet-19	117	40	45	45	NUM
admet-19	117	41	.	.	PUNCT
admet-19	118	1	[	[	X
admet-19	118	2	7	7	NUM
admet-19	118	3	]	]	X
admet-19	118	4	iso	iso	NOUN
admet-19	118	5	14971:2007	14971:2007	NUM
admet-19	118	6	medical	medical	ADJ
admet-19	118	7	devices	device	NOUN
admet-19	118	8	–	–	PUNCT
admet-19	118	9	application	application	NOUN
admet-19	118	10	of	of	ADP
admet-19	118	11	risk	risk	NOUN
admet-19	118	12	management	management	NOUN
admet-19	118	13	to	to	ADP
admet-19	118	14	medical	medical	ADJ
admet-19	118	15	devices	device	NOUN
admet-19	118	16	(	(	PUNCT
admet-19	118	17	2007	2007	NUM
admet-19	118	18	)	)	PUNCT
admet-19	119	1	[	[	X
admet-19	119	2	8	8	NUM
admet-19	119	3	]	]	X
admet-19	119	4	ansi	ansi	PROPN
admet-19	119	5	/	/	SYM
admet-19	119	6	aami	aami	PROPN
admet-19	119	7	/	/	SYM
admet-19	119	8	iec	iec	PROPN
admet-19	119	9	62366:2007	62366:2007	NUM
admet-19	119	10	medical	medical	ADJ
admet-19	119	11	devices	device	NOUN
admet-19	119	12	–	–	PUNCT
admet-19	119	13	application	application	NOUN
admet-19	119	14	of	of	ADP
admet-19	119	15	usability	usability	NOUN
admet-19	119	16	engineering	engineering	NOUN
admet-19	119	17	to	to	ADP
admet-19	119	18	medical	medical	ADJ
admet-19	119	19	devices	device	NOUN
admet-19	119	20	(	(	PUNCT
admet-19	119	21	2007	2007	NUM
admet-19	119	22	)	)	PUNCT
admet-19	120	1	[	[	X
admet-19	120	2	9	9	NUM
admet-19	120	3	]	]	X
admet-19	120	4	ansi	ansi	PROPN
admet-19	120	5	/	/	SYM
admet-19	120	6	aami	aami	PROPN
admet-19	120	7	he	he	PRON
admet-19	121	1	75:2009	75:2009	NUM
admet-19	121	2	human	human	ADJ
admet-19	121	3	factors	factor	NOUN
admet-19	121	4	engineering	engineering	NOUN
admet-19	121	5	–	–	PUNCT
admet-19	121	6	design	design	NOUN
admet-19	121	7	of	of	ADP
admet-19	121	8	medical	medical	ADJ
admet-19	121	9	devices	device	NOUN
admet-19	121	10	(	(	PUNCT
admet-19	121	11	2009	2009	NUM
admet-19	121	12	)	)	PUNCT
admet-19	122	1	[	[	X
admet-19	122	2	10	10	NUM
admet-19	122	3	]	]	X
admet-19	122	4	a.d	a.d	PROPN
admet-19	122	5	.	.	PROPN
admet-19	122	6	maynard	maynard	PROPN
admet-19	122	7	,	,	PUNCT
admet-19	122	8	e.d	e.d	PROPN
admet-19	122	9	.	.	PROPN
admet-19	122	10	kuempel	kuempel	PROPN
admet-19	122	11	,	,	PUNCT
admet-19	122	12	journal	journal	NOUN
admet-19	122	13	of	of	ADP
admet-19	122	14	nanoparticle	nanoparticle	NOUN
admet-19	122	15	research	research	NOUN
admet-19	122	16	7	7	NUM
admet-19	122	17	(	(	PUNCT
admet-19	122	18	2005	2005	NUM
admet-19	122	19	)	)	PUNCT
admet-19	122	20	587	587	NUM
admet-19	122	21	-	-	SYM
admet-19	122	22	614	614	NUM
admet-19	122	23	.	.	PUNCT
admet-19	123	1	[	[	X
admet-19	123	2	11	11	NUM
admet-19	123	3	]	]	X
admet-19	123	4	a.d	a.d	PROPN
admet-19	123	5	.	.	PROPN
admet-19	123	6	maynard	maynard	PROPN
admet-19	123	7	,	,	PUNCT
admet-19	123	8	p.a	p.a	PROPN
admet-19	123	9	.	.	PROPN
admet-19	123	10	baron	baron	PROPN
admet-19	123	11	,	,	PUNCT
admet-19	123	12	m.	m.	NOUN
admet-19	123	13	foley	foley	PROPN
admet-19	123	14	,	,	PUNCT
admet-19	123	15	a.a	a.a	PROPN
admet-19	123	16	.	.	PROPN
admet-19	123	17	shvedova	shvedova	PROPN
admet-19	123	18	,	,	PUNCT
admet-19	123	19	e.r	e.r	PROPN
admet-19	123	20	.	.	PROPN
admet-19	123	21	kisin	kisin	PROPN
admet-19	123	22	,	,	PUNCT
admet-19	123	23	v.	v.	ADP
admet-19	123	24	castranova	castranova	NOUN
admet-19	123	25	,	,	PUNCT
admet-19	123	26	journal	journal	NOUN
admet-19	123	27	of	of	ADP
admet-19	123	28	toxicology	toxicology	NOUN
admet-19	123	29	and	and	CCONJ
admet-19	123	30	environmental	environmental	ADJ
admet-19	123	31	health	health	NOUN
admet-19	123	32	a	a	DET
admet-19	123	33	67	67	NUM
admet-19	123	34	(	(	PUNCT
admet-19	123	35	2004	2004	NUM
admet-19	123	36	)	)	PUNCT
admet-19	123	37	87	87	NUM
admet-19	123	38	-	-	SYM
admet-19	123	39	107	107	NUM
admet-19	123	40	.	.	PUNCT
admet-19	124	1	[	[	X
admet-19	124	2	12	12	NUM
admet-19	124	3	]	]	X
admet-19	124	4	d.b	d.b	PROPN
admet-19	124	5	.	.	PROPN
admet-19	124	6	warheit	warheit	PROPN
admet-19	124	7	,	,	PUNCT
admet-19	124	8	k.l	k.l	PROPN
admet-19	124	9	.	.	PROPN
admet-19	124	10	reed	reed	PROPN
admet-19	124	11	,	,	PUNCT
admet-19	124	12	t.r	t.r	PROPN
admet-19	124	13	.	.	PROPN
admet-19	124	14	webb	webb	PROPN
admet-19	124	15	,	,	PUNCT
admet-19	124	16	experimental	experimental	ADJ
admet-19	124	17	lung	lung	NOUN
admet-19	124	18	research	research	NOUN
admet-19	124	19	29	29	NUM
admet-19	124	20	(	(	PUNCT
admet-19	124	21	2003	2003	NUM
admet-19	124	22	)	)	PUNCT
admet-19	124	23	593	593	NUM
admet-19	124	24	-	-	NUM
admet-19	124	25	606	606	NUM
admet-19	124	26	.	.	PUNCT
admet-19	125	1	[	[	X
admet-19	125	2	13	13	NUM
admet-19	125	3	]	]	PUNCT
admet-19	125	4	etc	etc	X
admet-19	125	5	group	group	NOUN
admet-19	125	6	,	,	PUNCT
admet-19	125	7	no	no	DET
admet-19	125	8	small	small	ADJ
admet-19	125	9	matter	matter	NOUN
admet-19	125	10	ii	ii	NOUN
admet-19	125	11	:	:	PUNCT
admet-19	125	12	the	the	DET
admet-19	125	13	case	case	NOUN
admet-19	125	14	for	for	ADP
admet-19	125	15	a	a	DET
admet-19	125	16	global	global	ADJ
admet-19	125	17	moratorium	moratorium	NOUN
admet-19	125	18	size	size	NOUN
admet-19	125	19	matters	matter	NOUN
admet-19	125	20	!	!	PUNCT
admet-19	126	1	(	(	PUNCT
admet-19	126	2	2003	2003	NUM
admet-19	126	3	)	)	PUNCT
admet-19	127	1	©	©	PROPN
admet-19	127	2	2013	2013	NUM
admet-19	127	3	by	by	ADP
admet-19	127	4	the	the	DET
admet-19	127	5	authors	author	NOUN
admet-19	127	6	;	;	PUNCT
admet-19	127	7	licensee	licensee	PROPN
admet-19	127	8	iapc	iapc	PROPN
admet-19	127	9	,	,	PUNCT
admet-19	127	10	zagreb	zagreb	PROPN
admet-19	127	11	,	,	PUNCT
admet-19	127	12	croatia	croatia	PROPN
admet-19	127	13	.	.	PUNCT
admet-19	128	1	this	this	DET
admet-19	128	2	article	article	NOUN
admet-19	128	3	is	be	AUX
admet-19	128	4	an	an	DET
admet-19	128	5	open	open	ADJ
admet-19	128	6	-	-	PUNCT
admet-19	128	7	access	access	NOUN
admet-19	128	8	article	article	NOUN
admet-19	128	9	distributed	distribute	VERB
admet-19	128	10	under	under	ADP
admet-19	128	11	the	the	DET
admet-19	128	12	terms	term	NOUN
admet-19	128	13	and	and	CCONJ
admet-19	128	14	conditions	condition	NOUN
admet-19	128	15	of	of	ADP
admet-19	128	16	the	the	DET
admet-19	128	17	creative	creative	ADJ
admet-19	128	18	commons	common	NOUN
admet-19	128	19	attribution	attribution	NOUN
admet-19	128	20	license	license	NOUN
admet-19	129	1	(	(	PUNCT
admet-19	129	2	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
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