id	sid	tid	token	lemma	pos
admet-2	1	1	jese	jese	PROPN
admet-2	1	2	manuscript	manuscript	PROPN
admet-2	1	3	doi	doi	PROPN
admet-2	1	4	:	:	PUNCT
admet-2	1	5	10.5599	10.5599	NUM
admet-2	1	6	/	/	SYM
admet-2	1	7	admet.1.1.2	admet.1.1.2	NOUN
admet-2	1	8	3	3	NUM
admet-2	1	9	admet	admet	X
admet-2	1	10	&	&	CCONJ
admet-2	1	11	dmpk	dmpk	PROPN
admet-2	1	12	1(1	1(1	NUM
admet-2	1	13	)	)	PUNCT
admet-2	1	14	(	(	PUNCT
admet-2	1	15	2013	2013	NUM
admet-2	1	16	)	)	PUNCT
admet-2	1	17	3	3	NUM
admet-2	1	18	-	-	SYM
admet-2	1	19	5	5	NUM
admet-2	1	20	;	;	PUNCT
admet-2	1	21	doi	doi	NOUN
admet-2	1	22	:	:	PUNCT
admet-2	1	23	10.5599	10.5599	NUM
admet-2	1	24	/	/	SYM
admet-2	1	25	admet.1.1.2	admet.1.1.2	ADJ
admet-2	1	26	open	open	ADJ
admet-2	1	27	access	access	NOUN
admet-2	1	28	:	:	PUNCT
admet-2	1	29	issn	issn	NOUN
admet-2	1	30	:	:	PUNCT
admet-2	1	31	1848	1848	NUM
admet-2	1	32	-	-	SYM
admet-2	1	33	7718	7718	NUM
admet-2	1	34	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-2	1	35	book	book	NOUN
admet-2	1	36	review	review	NOUN
admet-2	1	37	finding	find	VERB
admet-2	1	38	a	a	DET
admet-2	1	39	needle	needle	NOUN
admet-2	1	40	in	in	ADP
admet-2	1	41	a	a	DET
admet-2	1	42	haystack	haystack	NOUN
admet-2	1	43	zoran	zoran	NOUN
admet-2	1	44	mandić	mandić	PROPN
admet-2	1	45	faculty	faculty	NOUN
admet-2	1	46	of	of	ADP
admet-2	1	47	chemical	chemical	ADJ
admet-2	1	48	engineering	engineering	NOUN
admet-2	1	49	and	and	CCONJ
admet-2	1	50	technology	technology	NOUN
admet-2	1	51	,	,	PUNCT
admet-2	1	52	university	university	PROPN
admet-2	1	53	of	of	ADP
admet-2	1	54	zagreb	zagreb	PROPN
admet-2	1	55	,	,	PUNCT
admet-2	1	56	marulićev	marulićev	PROPN
admet-2	1	57	trg	trg	PROPN
admet-2	1	58	19	19	NUM
admet-2	1	59	,	,	PUNCT
admet-2	1	60	hr-10000	hr-10000	PROPN
admet-2	1	61	zagreb	zagreb	PROPN
admet-2	1	62	,	,	PUNCT
admet-2	1	63	croatia	croatia	PROPN
admet-2	1	64	e	e	NOUN
admet-2	1	65	-	-	NOUN
admet-2	1	66	mail	mail	NOUN
admet-2	1	67	:	:	PUNCT
admet-2	1	68	zmandic@fkit.hr	zmandic@fkit.hr	PROPN
admet-2	1	69	;	;	PUNCT
admet-2	1	70	tel	tel	PROPN
admet-2	1	71	.	.	PUNCT
admet-2	1	72	:	:	PUNCT
admet-2	2	1	+385	+385	PROPN
admet-2	2	2	-	-	SYM
admet-2	2	3	1	1	NUM
admet-2	2	4	-	-	PUNCT
admet-2	2	5	4597	4597	NUM
admet-2	2	6	-	-	SYM
admet-2	2	7	164	164	NUM
admet-2	2	8	;	;	PUNCT
admet-2	2	9	fax	fax	NOUN
admet-2	2	10	:	:	PUNCT
admet-2	2	11	+385	+385	ADJ
admet-2	2	12	-	-	PUNCT
admet-2	2	13	1	1	NUM
admet-2	2	14	-	-	PUNCT
admet-2	2	15	3733	3733	NUM
admet-2	2	16	-	-	SYM
admet-2	2	17	640	640	NUM
admet-2	2	18	received	receive	VERB
admet-2	2	19	:	:	PUNCT
admet-2	2	20	december	december	PROPN
admet-2	2	21	20	20	NUM
admet-2	2	22	,	,	PUNCT
admet-2	2	23	2013	2013	NUM
admet-2	2	24	;	;	PUNCT
admet-2	2	25	revised	revise	VERB
admet-2	2	26	:	:	PUNCT
admet-2	2	27	january	january	PROPN
admet-2	2	28	10	10	NUM
admet-2	2	29	,	,	PUNCT
admet-2	2	30	2013	2013	NUM
admet-2	2	31	;	;	PUNCT
admet-2	2	32	published	publish	VERB
admet-2	2	33	:	:	PUNCT
admet-2	2	34	january	january	PROPN
admet-2	2	35	14	14	NUM
admet-2	2	36	,	,	PUNCT
admet-2	2	37	2013	2013	NUM
admet-2	2	38	absorption	absorption	NOUN
admet-2	2	39	and	and	CCONJ
admet-2	2	40	drug	drug	NOUN
admet-2	2	41	development	development	NOUN
admet-2	2	42	.	.	PUNCT
admet-2	3	1	solubility	solubility	NOUN
admet-2	3	2	,	,	PUNCT
admet-2	3	3	permeability	permeability	NOUN
admet-2	3	4	and	and	CCONJ
admet-2	3	5	charge	charge	NOUN
admet-2	3	6	state	state	NOUN
admet-2	3	7	.	.	PUNCT
admet-2	4	1	2nd	2nd	PROPN
admet-2	4	2	edition	edition	PROPN
admet-2	4	3	.	.	PUNCT
admet-2	5	1	alex	alex	PROPN
admet-2	5	2	avdeef	avdeef	PROPN
admet-2	5	3	,	,	PUNCT
admet-2	5	4	john	john	PROPN
admet-2	5	5	wiley	wiley	PROPN
admet-2	5	6	&	&	CCONJ
admet-2	5	7	sons	sons	PROPN
admet-2	5	8	inc	inc	PROPN
admet-2	5	9	.	.	PROPN
admet-2	5	10	2012	2012	NUM
admet-2	5	11	.	.	PUNCT
admet-2	6	1	in	in	ADP
admet-2	6	2	my	my	PRON
admet-2	6	3	early	early	ADJ
admet-2	6	4	days	day	NOUN
admet-2	6	5	in	in	ADP
admet-2	6	6	pharmaceutical	pharmaceutical	ADJ
admet-2	6	7	research	research	NOUN
admet-2	6	8	i	i	PRON
admet-2	6	9	was	be	AUX
admet-2	6	10	summoned	summon	VERB
admet-2	6	11	into	into	ADP
admet-2	6	12	the	the	DET
admet-2	6	13	boss	boss	NOUN
admet-2	6	14	's	's	PART
admet-2	6	15	office	office	NOUN
admet-2	6	16	where	where	SCONJ
admet-2	6	17	a	a	DET
admet-2	6	18	meeting	meeting	NOUN
admet-2	6	19	was	be	AUX
admet-2	6	20	taking	take	VERB
admet-2	6	21	place	place	NOUN
admet-2	6	22	.	.	PUNCT
admet-2	7	1	i	i	PRON
admet-2	7	2	came	come	VERB
admet-2	7	3	right	right	ADV
admet-2	7	4	into	into	ADP
admet-2	7	5	a	a	DET
admet-2	7	6	discussion	discussion	NOUN
admet-2	7	7	about	about	ADP
admet-2	7	8	the	the	DET
admet-2	7	9	determination	determination	NOUN
admet-2	7	10	of	of	ADP
admet-2	7	11	the	the	DET
admet-2	7	12	partition	partition	NOUN
admet-2	7	13	coefficients	coefficient	NOUN
admet-2	7	14	of	of	ADP
admet-2	7	15	two	two	NUM
admet-2	7	16	substances	substance	NOUN
admet-2	7	17	of	of	ADP
admet-2	7	18	potential	potential	ADJ
admet-2	7	19	significance	significance	NOUN
admet-2	7	20	to	to	ADP
admet-2	7	21	the	the	DET
admet-2	7	22	company	company	NOUN
admet-2	7	23	.	.	PUNCT
admet-2	8	1	“	"	PUNCT
admet-2	8	2	this	this	PRON
admet-2	8	3	is	be	AUX
admet-2	8	4	a	a	DET
admet-2	8	5	notorious	notorious	ADJ
admet-2	8	6	time	time	NOUN
admet-2	8	7	wasting	waste	VERB
admet-2	8	8	”	"	PUNCT
admet-2	8	9	,	,	PUNCT
admet-2	8	10	i	i	PRON
admet-2	8	11	muttered	mutter	VERB
admet-2	8	12	to	to	ADP
admet-2	8	13	myself	myself	PRON
admet-2	8	14	while	while	SCONJ
admet-2	8	15	trying	try	VERB
admet-2	8	16	to	to	PART
admet-2	8	17	avoid	avoid	VERB
admet-2	8	18	being	be	AUX
admet-2	8	19	drawn	draw	VERB
admet-2	8	20	into	into	ADP
admet-2	8	21	the	the	DET
admet-2	8	22	discussion	discussion	NOUN
admet-2	8	23	.	.	PUNCT
admet-2	9	1	what	what	PRON
admet-2	9	2	would	would	AUX
admet-2	9	3	have	have	AUX
admet-2	9	4	been	be	AUX
admet-2	9	5	more	more	ADV
admet-2	9	6	important	important	ADJ
admet-2	9	7	was	be	AUX
admet-2	9	8	the	the	DET
admet-2	9	9	synthesis	synthesis	NOUN
admet-2	9	10	of	of	ADP
admet-2	9	11	new	new	ADJ
admet-2	9	12	chemical	chemical	NOUN
admet-2	9	13	entities	entity	NOUN
admet-2	9	14	,	,	PUNCT
admet-2	9	15	which	which	PRON
admet-2	9	16	certainly	certainly	ADV
admet-2	9	17	had	have	VERB
admet-2	9	18	very	very	ADV
admet-2	9	19	good	good	ADJ
admet-2	9	20	potential	potential	NOUN
admet-2	9	21	to	to	PART
admet-2	9	22	become	become	VERB
admet-2	9	23	new	new	ADJ
admet-2	9	24	blockbusters	blockbuster	NOUN
admet-2	9	25	on	on	ADP
admet-2	9	26	the	the	DET
admet-2	9	27	drugs	drug	NOUN
admet-2	9	28	market	market	NOUN
admet-2	9	29	,	,	PUNCT
admet-2	9	30	especially	especially	ADV
admet-2	9	31	those	those	PRON
admet-2	9	32	originating	originate	VERB
admet-2	9	33	from	from	ADP
admet-2	9	34	my	my	PRON
admet-2	9	35	flask	flask	NOUN
admet-2	9	36	.	.	PUNCT
admet-2	10	1	little	little	ADJ
admet-2	10	2	did	do	AUX
admet-2	10	3	i	i	PRON
admet-2	10	4	know	know	VERB
admet-2	10	5	at	at	ADP
admet-2	10	6	that	that	DET
admet-2	10	7	time	time	NOUN
admet-2	10	8	that	that	SCONJ
admet-2	10	9	the	the	DET
admet-2	10	10	issue	issue	NOUN
admet-2	10	11	of	of	ADP
admet-2	10	12	accurate	accurate	ADJ
admet-2	10	13	prediction	prediction	NOUN
admet-2	10	14	of	of	ADP
admet-2	10	15	drug	drug	NOUN
admet-2	10	16	absorption	absorption	NOUN
admet-2	10	17	in	in	ADP
admet-2	10	18	the	the	DET
admet-2	10	19	early	early	ADJ
admet-2	10	20	stages	stage	NOUN
admet-2	10	21	of	of	ADP
admet-2	10	22	drug	drug	NOUN
admet-2	10	23	discovery	discovery	NOUN
admet-2	10	24	would	would	AUX
admet-2	10	25	become	become	VERB
admet-2	10	26	so	so	ADV
admet-2	10	27	important	important	ADJ
admet-2	10	28	.	.	PUNCT
admet-2	11	1	it	it	PRON
admet-2	11	2	was	be	AUX
admet-2	11	3	only	only	ADV
admet-2	11	4	some	some	DET
admet-2	11	5	time	time	NOUN
admet-2	11	6	later	later	ADV
admet-2	11	7	,	,	PUNCT
admet-2	11	8	when	when	SCONJ
admet-2	11	9	a	a	DET
admet-2	11	10	colleague	colleague	NOUN
admet-2	11	11	threw	throw	VERB
admet-2	11	12	a	a	DET
admet-2	11	13	paper	paper	NOUN
admet-2	11	14	in	in	ADP
admet-2	11	15	front	front	NOUN
admet-2	11	16	of	of	ADP
admet-2	11	17	me	i	PRON
admet-2	11	18	claiming	claim	VERB
admet-2	11	19	excitedly	excitedly	ADV
admet-2	11	20	that	that	SCONJ
admet-2	11	21	it	it	PRON
admet-2	11	22	was	be	AUX
admet-2	11	23	something	something	PRON
admet-2	11	24	we	we	PRON
admet-2	11	25	could	could	AUX
admet-2	11	26	and	and	CCONJ
admet-2	11	27	should	should	AUX
admet-2	11	28	do	do	VERB
admet-2	11	29	,	,	PUNCT
admet-2	11	30	that	that	SCONJ
admet-2	11	31	i	i	PRON
admet-2	11	32	gave	give	VERB
admet-2	11	33	the	the	DET
admet-2	11	34	subject	subject	NOUN
admet-2	11	35	a	a	DET
admet-2	11	36	second	second	ADJ
admet-2	11	37	thought	thought	NOUN
admet-2	11	38	.	.	PUNCT
admet-2	12	1	it	it	PRON
admet-2	12	2	was	be	AUX
admet-2	12	3	one	one	NUM
admet-2	12	4	of	of	ADP
admet-2	12	5	a	a	DET
admet-2	12	6	series	series	NOUN
admet-2	12	7	of	of	ADP
admet-2	12	8	alex	alex	PROPN
admet-2	12	9	avdeef	avdeef	PROPN
admet-2	12	10	's	's	PART
admet-2	12	11	papers	paper	NOUN
admet-2	12	12	about	about	ADP
admet-2	12	13	physico	physico	NOUN
admet-2	12	14	-	-	PUNCT
admet-2	12	15	chemical	chemical	NOUN
admet-2	12	16	profiling	profiling	NOUN
admet-2	12	17	of	of	ADP
admet-2	12	18	drug	drug	NOUN
admet-2	12	19	substances	substance	NOUN
admet-2	12	20	including	include	VERB
admet-2	12	21	the	the	DET
admet-2	12	22	potentiometric	potentiometric	ADJ
admet-2	12	23	determination	determination	NOUN
admet-2	12	24	of	of	ADP
admet-2	12	25	octanol	octanol	NOUN
admet-2	12	26	–	–	PUNCT
admet-2	12	27	water	water	NOUN
admet-2	12	28	partition	partition	NOUN
admet-2	12	29	coefficients	coefficient	NOUN
admet-2	12	30	.	.	PUNCT
admet-2	13	1	it	it	PRON
admet-2	13	2	took	take	VERB
admet-2	13	3	no	no	DET
admet-2	13	4	time	time	NOUN
admet-2	13	5	for	for	SCONJ
admet-2	13	6	the	the	DET
admet-2	13	7	colleague	colleague	NOUN
admet-2	13	8	of	of	ADP
admet-2	13	9	mine	mine	PRON
admet-2	13	10	to	to	PART
admet-2	13	11	assemble	assemble	VERB
admet-2	13	12	a	a	DET
admet-2	13	13	potentiometric	potentiometric	ADJ
admet-2	13	14	titration	titration	NOUN
admet-2	13	15	device	device	NOUN
admet-2	13	16	from	from	ADP
admet-2	13	17	scraps	scrap	NOUN
admet-2	13	18	and	and	CCONJ
admet-2	13	19	pieces	piece	NOUN
admet-2	13	20	of	of	ADP
admet-2	13	21	old	old	ADJ
admet-2	13	22	,	,	PUNCT
admet-2	13	23	discarded	discard	VERB
admet-2	13	24	equipment	equipment	NOUN
admet-2	13	25	,	,	PUNCT
admet-2	13	26	and	and	CCONJ
admet-2	13	27	off	off	ADV
admet-2	13	28	we	we	PRON
admet-2	13	29	went	go	VERB
admet-2	13	30	...	...	PUNCT
admet-2	13	31	now	now	ADV
admet-2	13	32	,	,	PUNCT
admet-2	13	33	almost	almost	ADV
admet-2	13	34	two	two	NUM
admet-2	13	35	decades	decade	NOUN
admet-2	13	36	later	later	ADV
admet-2	13	37	,	,	PUNCT
admet-2	13	38	while	while	SCONJ
admet-2	13	39	flicking	flick	VERB
admet-2	13	40	through	through	ADP
admet-2	13	41	the	the	DET
admet-2	13	42	pages	page	NOUN
admet-2	13	43	of	of	ADP
admet-2	13	44	the	the	DET
admet-2	13	45	second	second	ADJ
admet-2	13	46	edition	edition	NOUN
admet-2	13	47	of	of	ADP
admet-2	13	48	alex	alex	PROPN
admet-2	13	49	's	's	PART
admet-2	13	50	book	book	NOUN
admet-2	13	51	absorption	absorption	NOUN
admet-2	13	52	and	and	CCONJ
admet-2	13	53	drug	drug	NOUN
admet-2	13	54	development	development	NOUN
admet-2	13	55	,	,	PUNCT
admet-2	13	56	i	i	PRON
admet-2	13	57	find	find	VERB
admet-2	13	58	myself	myself	PRON
admet-2	13	59	astonished	astonish	VERB
admet-2	13	60	by	by	ADP
admet-2	13	61	how	how	SCONJ
admet-2	13	62	much	much	ADJ
admet-2	13	63	the	the	DET
admet-2	13	64	concept	concept	NOUN
admet-2	13	65	of	of	ADP
admet-2	13	66	drug	drug	NOUN
admet-2	13	67	absorption	absorption	NOUN
admet-2	13	68	and	and	CCONJ
admet-2	13	69	its	its	PRON
admet-2	13	70	importance	importance	NOUN
admet-2	13	71	has	have	AUX
admet-2	13	72	progressed	progress	VERB
admet-2	13	73	into	into	ADP
admet-2	13	74	a	a	DET
admet-2	13	75	scientific	scientific	ADJ
admet-2	13	76	discipline	discipline	NOUN
admet-2	13	77	without	without	ADP
admet-2	13	78	which	which	PRON
admet-2	13	79	no	no	DET
admet-2	13	80	contemporary	contemporary	ADJ
admet-2	13	81	pharmaceutical	pharmaceutical	ADJ
admet-2	13	82	research	research	NOUN
admet-2	13	83	could	could	AUX
admet-2	13	84	be	be	AUX
admet-2	13	85	considered	consider	VERB
admet-2	13	86	.	.	PUNCT
admet-2	14	1	the	the	DET
admet-2	14	2	author	author	NOUN
admet-2	14	3	describes	describe	VERB
admet-2	14	4	in	in	ADP
admet-2	14	5	a	a	DET
admet-2	14	6	very	very	ADV
admet-2	14	7	simple	simple	ADJ
admet-2	14	8	way	way	NOUN
admet-2	14	9	four	four	NUM
admet-2	14	10	key	key	ADJ
admet-2	14	11	physicochemical	physicochemical	ADJ
admet-2	14	12	processes	process	NOUN
admet-2	14	13	,	,	PUNCT
admet-2	14	14	i.e.	i.e.	X
admet-2	14	15	ionization	ionization	NOUN
admet-2	14	16	,	,	PUNCT
admet-2	14	17	solubility	solubility	NOUN
admet-2	14	18	,	,	PUNCT
admet-2	14	19	lipophilicity	lipophilicity	NOUN
admet-2	14	20	and	and	CCONJ
admet-2	14	21	permeability	permeability	NOUN
admet-2	14	22	,	,	PUNCT
admet-2	14	23	which	which	PRON
admet-2	14	24	are	be	AUX
admet-2	14	25	of	of	ADP
admet-2	14	26	relevance	relevance	NOUN
admet-2	14	27	to	to	ADP
admet-2	14	28	the	the	DET
admet-2	14	29	absorption	absorption	NOUN
admet-2	14	30	of	of	ADP
admet-2	14	31	most	most	ADV
admet-2	14	32	orally	orally	ADV
admet-2	14	33	administered	administer	VERB
admet-2	14	34	drugs	drug	NOUN
admet-2	14	35	,	,	PUNCT
admet-2	14	36	and	and	CCONJ
admet-2	14	37	explains	explain	VERB
admet-2	14	38	various	various	ADJ
admet-2	14	39	relationships	relationship	NOUN
admet-2	14	40	among	among	ADP
admet-2	14	41	them	they	PRON
admet-2	14	42	.	.	PUNCT
admet-2	15	1	by	by	ADP
admet-2	15	2	the	the	DET
admet-2	15	3	application	application	NOUN
admet-2	15	4	of	of	ADP
admet-2	15	5	simple	simple	ADJ
admet-2	15	6	scientific	scientific	ADJ
admet-2	15	7	concepts	concept	NOUN
admet-2	15	8	of	of	ADP
admet-2	15	9	physico	physico	NOUN
admet-2	15	10	-	-	PUNCT
admet-2	15	11	chemical	chemical	NOUN
admet-2	15	12	profiling	profiling	NOUN
admet-2	15	13	and	and	CCONJ
admet-2	15	14	continuously	continuously	ADV
admet-2	15	15	placing	place	VERB
admet-2	15	16	them	they	PRON
admet-2	15	17	in	in	ADP
admet-2	15	18	the	the	DET
admet-2	15	19	drug	drug	NOUN
admet-2	15	20	development	development	NOUN
admet-2	15	21	setting	setting	NOUN
admet-2	15	22	,	,	PUNCT
admet-2	15	23	readers	reader	NOUN
admet-2	15	24	can	can	AUX
admet-2	15	25	easily	easily	ADV
admet-2	15	26	gain	gain	VERB
admet-2	15	27	deep	deep	ADJ
admet-2	15	28	understanding	understanding	NOUN
admet-2	15	29	of	of	ADP
admet-2	15	30	their	their	PRON
admet-2	15	31	significance	significance	NOUN
admet-2	15	32	.	.	PUNCT
admet-2	16	1	physicochemical	physicochemical	ADJ
admet-2	16	2	parameters	parameter	NOUN
admet-2	16	3	such	such	ADJ
admet-2	16	4	as	as	ADP
admet-2	16	5	pka	pka	PROPN
admet-2	16	6	,	,	PUNCT
admet-2	16	7	log	log	VERB
admet-2	16	8	p	p	NOUN
admet-2	16	9	or	or	CCONJ
admet-2	16	10	log	log	NOUN
admet-2	16	11	s	s	NOUN
admet-2	16	12	are	be	AUX
admet-2	16	13	no	no	ADV
admet-2	16	14	longer	long	ADV
admet-2	16	15	perceived	perceive	VERB
admet-2	16	16	by	by	ADP
admet-2	16	17	medicinal	medicinal	ADJ
admet-2	16	18	chemists	chemist	NOUN
admet-2	16	19	or	or	CCONJ
admet-2	16	20	formulation	formulation	NOUN
admet-2	16	21	and	and	CCONJ
admet-2	16	22	pre	pre	ADJ
admet-2	16	23	-	-	ADJ
admet-2	16	24	formulation	formulation	ADJ
admet-2	16	25	engineers	engineer	NOUN
admet-2	16	26	as	as	ADP
admet-2	16	27	“	"	PUNCT
admet-2	16	28	good	good	ADJ
admet-2	16	29	”	"	PUNCT
admet-2	16	30	or	or	CCONJ
admet-2	16	31	“	"	PUNCT
admet-2	16	32	bad	bad	ADJ
admet-2	16	33	”	"	PUNCT
admet-2	16	34	numbers	number	NOUN
admet-2	16	35	,	,	PUNCT
admet-2	16	36	but	but	CCONJ
admet-2	16	37	provide	provide	VERB
admet-2	16	38	valuable	valuable	ADJ
admet-2	16	39	information	information	NOUN
admet-2	16	40	revealing	reveal	VERB
admet-2	16	41	and	and	CCONJ
admet-2	16	42	predicting	predict	VERB
admet-2	16	43	the	the	DET
admet-2	16	44	whole	whole	ADJ
admet-2	16	45	pathway	pathway	NOUN
admet-2	16	46	and	and	CCONJ
admet-2	16	47	the	the	DET
admet-2	16	48	fate	fate	NOUN
admet-2	16	49	of	of	ADP
admet-2	16	50	the	the	DET
admet-2	16	51	drug	drug	NOUN
admet-2	16	52	from	from	ADP
admet-2	16	53	its	its	PRON
admet-2	16	54	administration	administration	NOUN
admet-2	16	55	to	to	ADP
admet-2	16	56	entering	enter	VERB
admet-2	16	57	the	the	DET
admet-2	16	58	bloodstream	bloodstream	NOUN
admet-2	16	59	.	.	PUNCT
admet-2	17	1	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-2	17	2	�	�	PROPN
admet-2	17	3	mailto:zmandic@fkit.hr	mailto:zmandic@fkit.hr	PROPN
admet-2	17	4	�	�	PROPN
admet-2	17	5	zoran	zoran	PROPN
admet-2	17	6	mandić	mandić	PROPN
admet-2	17	7	admet	admet	PROPN
admet-2	17	8	&	&	CCONJ
admet-2	17	9	dmpk	dmpk	PROPN
admet-2	17	10	1(1	1(1	NUM
admet-2	17	11	)	)	PUNCT
admet-2	17	12	(	(	PUNCT
admet-2	17	13	2013	2013	NUM
admet-2	17	14	)	)	PUNCT
admet-2	17	15	3	3	NUM
admet-2	17	16	-	-	SYM
admet-2	17	17	5	5	NUM
admet-2	17	18	4	4	NUM
admet-2	17	19	this	this	DET
admet-2	17	20	book	book	NOUN
admet-2	17	21	is	be	AUX
admet-2	17	22	based	base	VERB
admet-2	17	23	on	on	ADP
admet-2	17	24	the	the	DET
admet-2	17	25	author	author	NOUN
admet-2	17	26	’s	’s	PART
admet-2	17	27	many	many	ADJ
admet-2	17	28	years	year	NOUN
admet-2	17	29	of	of	ADP
admet-2	17	30	experience	experience	NOUN
admet-2	17	31	and	and	CCONJ
admet-2	17	32	on	on	ADP
admet-2	17	33	the	the	DET
admet-2	17	34	experience	experience	NOUN
admet-2	17	35	of	of	ADP
admet-2	17	36	many	many	ADJ
admet-2	17	37	other	other	ADJ
admet-2	17	38	scientists	scientist	NOUN
admet-2	17	39	who	who	PRON
admet-2	17	40	have	have	AUX
admet-2	17	41	tackled	tackle	VERB
admet-2	17	42	the	the	DET
admet-2	17	43	subject	subject	NOUN
admet-2	17	44	of	of	ADP
admet-2	17	45	drug	drug	NOUN
admet-2	17	46	absorption	absorption	NOUN
admet-2	17	47	and	and	CCONJ
admet-2	17	48	given	give	VERB
admet-2	17	49	it	it	PRON
admet-2	17	50	the	the	DET
admet-2	17	51	significance	significance	NOUN
admet-2	17	52	it	it	PRON
admet-2	17	53	deserves	deserve	VERB
admet-2	17	54	.	.	PUNCT
admet-2	18	1	if	if	SCONJ
admet-2	18	2	the	the	DET
admet-2	18	3	author	author	NOUN
admet-2	18	4	’s	’s	PART
admet-2	18	5	goal	goal	NOUN
admet-2	18	6	was	be	AUX
admet-2	18	7	to	to	PART
admet-2	18	8	“	"	PUNCT
admet-2	18	9	examine	examine	VERB
admet-2	18	10	the	the	DET
admet-2	18	11	components	component	NOUN
admet-2	18	12	of	of	ADP
admet-2	18	13	multimechanistic	multimechanistic	ADJ
admet-2	18	14	processes	process	NOUN
admet-2	18	15	related	relate	VERB
admet-2	18	16	to	to	PART
admet-2	18	17	charge	charge	VERB
admet-2	18	18	state	state	NOUN
admet-2	18	19	…	…	PUNCT
admet-2	18	20	.	.	PUNCT
admet-2	19	1	with	with	ADP
admet-2	19	2	the	the	DET
admet-2	19	3	aim	aim	NOUN
admet-2	19	4	of	of	ADP
admet-2	19	5	advancing	advance	VERB
admet-2	19	6	improved	improved	ADJ
admet-2	19	7	strategies	strategy	NOUN
admet-2	19	8	for	for	ADP
admet-2	19	9	in	in	ADP
admet-2	19	10	vitro	vitro	X
admet-2	19	11	assays	assay	NOUN
admet-2	19	12	related	relate	VERB
admet-2	19	13	to	to	ADP
admet-2	19	14	drug	drug	NOUN
admet-2	19	15	absorption	absorption	NOUN
admet-2	19	16	”	"	PUNCT
admet-2	19	17	,	,	PUNCT
admet-2	19	18	then	then	ADV
admet-2	19	19	there	there	PRON
admet-2	19	20	is	be	VERB
admet-2	19	21	no	no	DET
admet-2	19	22	shadow	shadow	NOUN
admet-2	19	23	of	of	ADP
admet-2	19	24	doubt	doubt	NOUN
admet-2	19	25	that	that	SCONJ
admet-2	19	26	he	he	PRON
admet-2	19	27	achieved	achieve	VERB
admet-2	19	28	it	it	PRON
admet-2	19	29	.	.	PUNCT
admet-2	20	1	however	however	ADV
admet-2	20	2	,	,	PUNCT
admet-2	20	3	the	the	DET
admet-2	20	4	core	core	NOUN
admet-2	20	5	strength	strength	NOUN
admet-2	20	6	of	of	ADP
admet-2	20	7	absorption	absorption	NOUN
admet-2	20	8	and	and	CCONJ
admet-2	20	9	drug	drug	NOUN
admet-2	20	10	development	development	NOUN
admet-2	20	11	is	be	AUX
admet-2	20	12	that	that	SCONJ
admet-2	20	13	it	it	PRON
admet-2	20	14	provides	provide	VERB
admet-2	20	15	solid	solid	ADJ
admet-2	20	16	ground	ground	NOUN
admet-2	20	17	on	on	ADP
admet-2	20	18	which	which	PRON
admet-2	20	19	different	different	ADJ
admet-2	20	20	worlds	world	NOUN
admet-2	20	21	,	,	PUNCT
admet-2	20	22	embodied	embody	VERB
admet-2	20	23	in	in	ADP
admet-2	20	24	the	the	DET
admet-2	20	25	labs	lab	NOUN
admet-2	20	26	of	of	ADP
admet-2	20	27	medicinal	medicinal	ADJ
admet-2	20	28	chemists	chemist	NOUN
admet-2	20	29	,	,	PUNCT
admet-2	20	30	pharmaceutical	pharmaceutical	ADJ
admet-2	20	31	scientists	scientist	NOUN
admet-2	20	32	,	,	PUNCT
admet-2	20	33	analytical	analytical	ADJ
admet-2	20	34	chemists	chemist	NOUN
admet-2	20	35	and	and	CCONJ
admet-2	20	36	even	even	ADV
admet-2	20	37	pharma	pharma	NOUN
admet-2	20	38	managers	manager	NOUN
admet-2	20	39	,	,	PUNCT
admet-2	20	40	can	can	AUX
admet-2	20	41	understand	understand	VERB
admet-2	20	42	each	each	DET
admet-2	20	43	other	other	ADJ
admet-2	20	44	and	and	CCONJ
admet-2	20	45	together	together	ADV
admet-2	20	46	rationalize	rationalize	VERB
admet-2	20	47	the	the	DET
admet-2	20	48	results	result	NOUN
admet-2	20	49	obtained	obtain	VERB
admet-2	20	50	and	and	CCONJ
admet-2	20	51	their	their	PRON
admet-2	20	52	consequences	consequence	NOUN
admet-2	20	53	.	.	PUNCT
admet-2	21	1	the	the	DET
admet-2	21	2	book	book	NOUN
admet-2	21	3	is	be	AUX
admet-2	21	4	conceptually	conceptually	ADV
admet-2	21	5	organized	organize	VERB
admet-2	21	6	into	into	ADP
admet-2	21	7	ten	ten	NUM
admet-2	21	8	chapters	chapter	NOUN
admet-2	21	9	.	.	PUNCT
admet-2	22	1	chapter	chapter	NOUN
admet-2	22	2	1	1	NUM
admet-2	22	3	is	be	AUX
admet-2	22	4	an	an	DET
admet-2	22	5	introductory	introductory	ADJ
admet-2	22	6	chapter	chapter	NOUN
admet-2	22	7	that	that	PRON
admet-2	22	8	places	place	VERB
admet-2	22	9	the	the	DET
admet-2	22	10	topic	topic	NOUN
admet-2	22	11	appropriately	appropriately	ADV
admet-2	22	12	in	in	ADP
admet-2	22	13	the	the	DET
admet-2	22	14	pharmaceutical	pharmaceutical	ADJ
admet-2	22	15	research	research	NOUN
admet-2	22	16	context	context	NOUN
admet-2	22	17	.	.	PUNCT
admet-2	23	1	chapter	chapter	NOUN
admet-2	23	2	2	2	NUM
admet-2	23	3	gives	give	VERB
admet-2	23	4	a	a	DET
admet-2	23	5	physico	physico	NOUN
admet-2	23	6	-	-	PUNCT
admet-2	23	7	chemical	chemical	NOUN
admet-2	23	8	model	model	NOUN
admet-2	23	9	of	of	ADP
admet-2	23	10	drug	drug	NOUN
admet-2	23	11	permeation	permeation	NOUN
admet-2	23	12	based	base	VERB
admet-2	23	13	on	on	ADP
admet-2	23	14	the	the	DET
admet-2	23	15	ph	ph	ADJ
admet-2	23	16	–	–	PUNCT
admet-2	23	17	partition	partition	NOUN
admet-2	23	18	hypothesis	hypothesis	NOUN
admet-2	23	19	and	and	CCONJ
admet-2	23	20	fick	fick	NOUN
admet-2	23	21	’s	’s	PART
admet-2	23	22	laws	law	NOUN
admet-2	23	23	of	of	ADP
admet-2	23	24	diffusion	diffusion	NOUN
admet-2	23	25	.	.	PUNCT
admet-2	24	1	this	this	PRON
admet-2	24	2	is	be	AUX
admet-2	24	3	followed	follow	VERB
admet-2	24	4	by	by	ADP
admet-2	24	5	a	a	DET
admet-2	24	6	description	description	NOUN
admet-2	24	7	of	of	ADP
admet-2	24	8	biological	biological	ADJ
admet-2	24	9	environments	environment	NOUN
admet-2	24	10	relevant	relevant	ADJ
admet-2	24	11	to	to	ADP
admet-2	24	12	drug	drug	NOUN
admet-2	24	13	absorption	absorption	NOUN
admet-2	24	14	.	.	PUNCT
admet-2	25	1	molecular	molecular	ADJ
admet-2	25	2	ionization	ionization	NOUN
admet-2	25	3	and	and	CCONJ
admet-2	25	4	the	the	DET
admet-2	25	5	acid	acid	NOUN
admet-2	25	6	-	-	PUNCT
admet-2	25	7	base	base	NOUN
admet-2	25	8	properties	property	NOUN
admet-2	25	9	of	of	ADP
admet-2	25	10	drugs	drug	NOUN
admet-2	25	11	are	be	AUX
admet-2	25	12	dealt	deal	VERB
admet-2	25	13	with	with	ADP
admet-2	25	14	in	in	ADP
admet-2	25	15	chapter	chapter	NOUN
admet-2	25	16	3	3	NUM
admet-2	25	17	.	.	PUNCT
admet-2	26	1	this	this	DET
admet-2	26	2	chapter	chapter	NOUN
admet-2	26	3	is	be	AUX
admet-2	26	4	the	the	DET
admet-2	26	5	most	most	ADV
admet-2	26	6	comprehensive	comprehensive	ADJ
admet-2	26	7	coverage	coverage	NOUN
admet-2	26	8	of	of	ADP
admet-2	26	9	the	the	DET
admet-2	26	10	theory	theory	NOUN
admet-2	26	11	and	and	CCONJ
admet-2	26	12	practical	practical	ADJ
admet-2	26	13	aspects	aspect	NOUN
admet-2	26	14	of	of	ADP
admet-2	26	15	pka	pka	PROPN
admet-2	26	16	determination	determination	NOUN
admet-2	26	17	by	by	ADP
admet-2	26	18	potentiometric	potentiometric	ADJ
admet-2	26	19	techniques	technique	NOUN
admet-2	26	20	i	i	PRON
admet-2	26	21	have	have	AUX
admet-2	26	22	ever	ever	ADV
admet-2	26	23	encountered	encounter	VERB
admet-2	26	24	in	in	ADP
admet-2	26	25	textbooks	textbook	NOUN
admet-2	26	26	of	of	ADP
admet-2	26	27	physical	physical	ADJ
admet-2	26	28	chemistry	chemistry	NOUN
admet-2	26	29	.	.	PUNCT
admet-2	27	1	from	from	ADP
admet-2	27	2	the	the	DET
admet-2	27	3	beginning	beginning	NOUN
admet-2	27	4	of	of	ADP
admet-2	27	5	the	the	DET
admet-2	27	6	chapter	chapter	NOUN
admet-2	27	7	readers	reader	NOUN
admet-2	27	8	learn	learn	VERB
admet-2	27	9	the	the	DET
admet-2	27	10	importance	importance	NOUN
admet-2	27	11	of	of	ADP
admet-2	27	12	pka	pka	PROPN
admet-2	27	13	as	as	ADP
admet-2	27	14	a	a	DET
admet-2	27	15	molecular	molecular	ADJ
admet-2	27	16	property	property	NOUN
admet-2	27	17	defining	define	VERB
admet-2	27	18	the	the	DET
admet-2	27	19	charge	charge	NOUN
admet-2	27	20	state	state	NOUN
admet-2	27	21	of	of	ADP
admet-2	27	22	drug	drug	NOUN
admet-2	27	23	in	in	ADP
admet-2	27	24	various	various	ADJ
admet-2	27	25	parts	part	NOUN
admet-2	27	26	of	of	ADP
admet-2	27	27	the	the	DET
admet-2	27	28	body	body	NOUN
admet-2	27	29	.	.	PUNCT
admet-2	28	1	the	the	DET
admet-2	28	2	thermodynamics	thermodynamic	NOUN
admet-2	28	3	of	of	ADP
admet-2	28	4	ionization	ionization	NOUN
admet-2	28	5	reactions	reaction	NOUN
admet-2	28	6	are	be	AUX
admet-2	28	7	explained	explain	VERB
admet-2	28	8	followed	follow	VERB
admet-2	28	9	by	by	ADP
admet-2	28	10	a	a	DET
admet-2	28	11	description	description	NOUN
admet-2	28	12	of	of	ADP
admet-2	28	13	the	the	DET
admet-2	28	14	practical	practical	ADJ
admet-2	28	15	aspects	aspect	NOUN
admet-2	28	16	of	of	ADP
admet-2	28	17	pka	pka	PROPN
admet-2	28	18	measurements	measurement	NOUN
admet-2	28	19	that	that	PRON
admet-2	28	20	should	should	AUX
admet-2	28	21	be	be	AUX
admet-2	28	22	taken	take	VERB
admet-2	28	23	into	into	ADP
admet-2	28	24	account	account	NOUN
admet-2	28	25	while	while	SCONJ
admet-2	28	26	performing	perform	VERB
admet-2	28	27	pka	pka	PROPN
admet-2	28	28	determinations	determination	NOUN
admet-2	28	29	with	with	ADP
admet-2	28	30	a	a	DET
admet-2	28	31	glass	glass	NOUN
admet-2	28	32	electrode	electrode	NOUN
admet-2	28	33	.	.	PUNCT
admet-2	29	1	data	datum	NOUN
admet-2	29	2	handling	handling	NOUN
admet-2	29	3	and	and	CCONJ
admet-2	29	4	data	datum	NOUN
admet-2	29	5	presentation	presentation	NOUN
admet-2	29	6	are	be	AUX
admet-2	29	7	introduced	introduce	VERB
admet-2	29	8	with	with	ADP
admet-2	29	9	the	the	DET
admet-2	29	10	emphasis	emphasis	NOUN
admet-2	29	11	on	on	ADP
admet-2	29	12	avoiding	avoid	VERB
admet-2	29	13	errors	error	NOUN
admet-2	29	14	and	and	CCONJ
admet-2	29	15	false	false	ADJ
admet-2	29	16	results	result	NOUN
admet-2	29	17	.	.	PUNCT
admet-2	30	1	particular	particular	ADJ
admet-2	30	2	attention	attention	NOUN
admet-2	30	3	is	be	AUX
admet-2	30	4	paid	pay	VERB
admet-2	30	5	to	to	ADP
admet-2	30	6	coping	cope	VERB
admet-2	30	7	with	with	ADP
admet-2	30	8	challenges	challenge	NOUN
admet-2	30	9	and	and	CCONJ
admet-2	30	10	obstacles	obstacle	NOUN
admet-2	30	11	that	that	PRON
admet-2	30	12	might	might	AUX
admet-2	30	13	be	be	AUX
admet-2	30	14	encountered	encounter	VERB
admet-2	30	15	in	in	ADP
admet-2	30	16	pka	pka	PROPN
admet-2	30	17	determination	determination	NOUN
admet-2	30	18	of	of	ADP
admet-2	30	19	low	low	ADJ
admet-2	30	20	solubility	solubility	NOUN
admet-2	30	21	substances	substance	NOUN
admet-2	30	22	of	of	ADP
admet-2	30	23	pharmaceutical	pharmaceutical	ADJ
admet-2	30	24	interest	interest	NOUN
admet-2	30	25	.	.	PUNCT
admet-2	31	1	all	all	DET
admet-2	31	2	topics	topic	NOUN
admet-2	31	3	are	be	AUX
admet-2	31	4	accompanied	accompany	VERB
admet-2	31	5	with	with	ADP
admet-2	31	6	many	many	ADJ
admet-2	31	7	practical	practical	ADJ
admet-2	31	8	examples	example	NOUN
admet-2	31	9	and	and	CCONJ
admet-2	31	10	tutorials	tutorial	NOUN
admet-2	31	11	.	.	PUNCT
admet-2	32	1	chapters	chapter	NOUN
admet-2	32	2	4	4	NUM
admet-2	32	3	and	and	CCONJ
admet-2	32	4	5	5	NUM
admet-2	32	5	describe	describe	VERB
admet-2	32	6	lipophilicity	lipophilicity	NOUN
admet-2	32	7	as	as	ADP
admet-2	32	8	a	a	DET
admet-2	32	9	molecular	molecular	ADJ
admet-2	32	10	property	property	NOUN
admet-2	32	11	of	of	ADP
admet-2	32	12	considerable	considerable	ADJ
admet-2	32	13	importance	importance	NOUN
admet-2	32	14	in	in	ADP
admet-2	32	15	drug	drug	NOUN
admet-2	32	16	absorption	absorption	NOUN
admet-2	32	17	.	.	PUNCT
admet-2	33	1	octanol	octanol	NOUN
admet-2	33	2	–	–	PUNCT
admet-2	33	3	water	water	NOUN
admet-2	33	4	partitioning	partitioning	NOUN
admet-2	33	5	(	(	PUNCT
admet-2	33	6	chapter	chapter	NOUN
admet-2	33	7	4	4	NUM
admet-2	33	8	)	)	PUNCT
admet-2	33	9	and	and	CCONJ
admet-2	33	10	“	"	PUNCT
admet-2	33	11	biomimetic	biomimetic	ADJ
admet-2	33	12	”	"	PUNCT
admet-2	33	13	liposome	liposome	NOUN
admet-2	33	14	–	–	PUNCT
admet-2	33	15	water	water	NOUN
admet-2	33	16	partitioning	partitioning	NOUN
admet-2	33	17	(	(	PUNCT
admet-2	33	18	chapter	chapter	NOUN
admet-2	33	19	5	5	NUM
admet-2	33	20	)	)	PUNCT
admet-2	33	21	and	and	CCONJ
admet-2	33	22	their	their	PRON
admet-2	33	23	determinations	determination	NOUN
admet-2	33	24	are	be	AUX
admet-2	33	25	presented	present	VERB
admet-2	33	26	.	.	PUNCT
admet-2	34	1	special	special	ADJ
admet-2	34	2	emphasis	emphasis	NOUN
admet-2	34	3	is	be	AUX
admet-2	34	4	placed	place	VERB
admet-2	34	5	on	on	ADP
admet-2	34	6	ion	ion	NOUN
admet-2	34	7	-	-	PUNCT
admet-2	34	8	pair	pair	NOUN
admet-2	34	9	partitioning	partitioning	NOUN
admet-2	34	10	and	and	CCONJ
admet-2	34	11	its	its	PRON
admet-2	34	12	significance	significance	NOUN
admet-2	34	13	for	for	ADP
admet-2	34	14	drug	drug	NOUN
admet-2	34	15	absorption	absorption	NOUN
admet-2	34	16	.	.	PUNCT
admet-2	35	1	an	an	DET
admet-2	35	2	attempt	attempt	NOUN
admet-2	35	3	is	be	AUX
admet-2	35	4	made	make	VERB
admet-2	35	5	to	to	PART
admet-2	35	6	define	define	VERB
admet-2	35	7	new	new	ADJ
admet-2	35	8	concepts	concept	NOUN
admet-2	35	9	and	and	CCONJ
admet-2	35	10	explain	explain	VERB
admet-2	35	11	some	some	PRON
admet-2	35	12	of	of	ADP
admet-2	35	13	the	the	DET
admet-2	35	14	anomalies	anomaly	NOUN
admet-2	35	15	in	in	ADP
admet-2	35	16	lipophilicity	lipophilicity	NOUN
admet-2	35	17	results	result	NOUN
admet-2	35	18	.	.	PUNCT
admet-2	36	1	alex	alex	PROPN
admet-2	36	2	avdeef	avdeef	PROPN
admet-2	36	3	giving	give	VERB
admet-2	36	4	a	a	DET
admet-2	36	5	lecture	lecture	NOUN
admet-2	36	6	at	at	ADP
admet-2	36	7	the	the	DET
admet-2	36	8	1st	1st	ADJ
admet-2	36	9	world	world	NOUN
admet-2	36	10	conference	conference	NOUN
admet-2	36	11	on	on	ADP
admet-2	36	12	physico	physico	NOUN
admet-2	36	13	-	-	PUNCT
admet-2	36	14	chemical	chemical	NOUN
admet-2	36	15	methods	method	NOUN
admet-2	36	16	in	in	ADP
admet-2	36	17	drug	drug	NOUN
admet-2	36	18	discovery	discovery	NOUN
admet-2	36	19	and	and	CCONJ
admet-2	36	20	development	development	NOUN
admet-2	36	21	,	,	PUNCT
admet-2	36	22	organized	organize	VERB
admet-2	36	23	by	by	ADP
admet-2	36	24	iapc	iapc	PROPN
admet-2	36	25	in	in	ADP
admet-2	36	26	rovinj	rovinj	PROPN
admet-2	36	27	,	,	PUNCT
admet-2	36	28	croatia	croatia	PROPN
admet-2	36	29	,	,	PUNCT
admet-2	36	30	2009	2009	NUM
admet-2	36	31	.	.	PUNCT
admet-2	37	1	admet	admet	PROPN
admet-2	37	2	&	&	CCONJ
admet-2	37	3	dmpk	dmpk	PROPN
admet-2	37	4	1(1	1(1	NUM
admet-2	37	5	)	)	PUNCT
admet-2	37	6	(	(	PUNCT
admet-2	37	7	2013	2013	NUM
admet-2	37	8	)	)	PUNCT
admet-2	37	9	3	3	NUM
admet-2	37	10	-	-	SYM
admet-2	37	11	5	5	NUM
admet-2	37	12	book	book	NOUN
admet-2	37	13	review	review	NOUN
admet-2	37	14	doi	doi	NOUN
admet-2	37	15	:	:	PUNCT
admet-2	37	16	10.5599	10.5599	NUM
admet-2	37	17	/	/	SYM
admet-2	37	18	admet.1.1.2	admet.1.1.2	NOUN
admet-2	37	19	5	5	NUM
admet-2	37	20	an	an	DET
admet-2	37	21	in	in	ADP
admet-2	37	22	-	-	PUNCT
admet-2	37	23	depth	depth	NOUN
admet-2	37	24	discussion	discussion	NOUN
admet-2	37	25	of	of	ADP
admet-2	37	26	solubility	solubility	NOUN
admet-2	37	27	and	and	CCONJ
admet-2	37	28	its	its	PRON
admet-2	37	29	measurements	measurement	NOUN
admet-2	37	30	is	be	AUX
admet-2	37	31	presented	present	VERB
admet-2	37	32	in	in	ADP
admet-2	37	33	chapter	chapter	NOUN
admet-2	37	34	6	6	NUM
admet-2	37	35	.	.	PUNCT
admet-2	38	1	important	important	ADJ
admet-2	38	2	concepts	concept	NOUN
admet-2	38	3	are	be	AUX
admet-2	38	4	illustrated	illustrate	VERB
admet-2	38	5	with	with	ADP
admet-2	38	6	several	several	ADJ
admet-2	38	7	case	case	NOUN
admet-2	38	8	studies	study	NOUN
admet-2	38	9	.	.	PUNCT
admet-2	39	1	ph	ph	ADJ
admet-2	39	2	-	-	ADJ
admet-2	39	3	dependent	dependent	ADJ
admet-2	39	4	solubility	solubility	NOUN
admet-2	39	5	profiles	profile	NOUN
admet-2	39	6	are	be	AUX
admet-2	39	7	evaluated	evaluate	VERB
admet-2	39	8	and	and	CCONJ
admet-2	39	9	highthroughput	highthroughput	VERB
admet-2	39	10	solubility	solubility	NOUN
admet-2	39	11	measurements	measurement	NOUN
admet-2	39	12	are	be	AUX
admet-2	39	13	tackled	tackle	VERB
admet-2	39	14	.	.	PUNCT
admet-2	40	1	chapters	chapter	NOUN
admet-2	40	2	7–9	7–9	NUM
admet-2	40	3	deal	deal	VERB
admet-2	40	4	with	with	ADP
admet-2	40	5	the	the	DET
admet-2	40	6	concepts	concept	NOUN
admet-2	40	7	of	of	ADP
admet-2	40	8	permeability	permeability	NOUN
admet-2	40	9	.	.	PUNCT
admet-2	41	1	the	the	DET
admet-2	41	2	practical	practical	ADJ
admet-2	41	3	and	and	CCONJ
admet-2	41	4	theoretical	theoretical	ADJ
admet-2	41	5	background	background	NOUN
admet-2	41	6	of	of	ADP
admet-2	41	7	prediction	prediction	NOUN
admet-2	41	8	of	of	ADP
admet-2	41	9	human	human	ADJ
admet-2	41	10	jejunal	jejunal	ADJ
admet-2	41	11	permeability	permeability	NOUN
admet-2	41	12	and	and	CCONJ
admet-2	41	13	human	human	ADJ
admet-2	41	14	intestinal	intestinal	ADJ
admet-2	41	15	absorption	absorption	NOUN
admet-2	41	16	by	by	ADP
admet-2	41	17	in	in	ADP
admet-2	41	18	-	-	PUNCT
admet-2	41	19	vitro	vitro	X
admet-2	41	20	assays	assay	NOUN
admet-2	41	21	,	,	PUNCT
admet-2	41	22	most	most	ADV
admet-2	41	23	notably	notably	ADV
admet-2	41	24	by	by	ADP
admet-2	41	25	pampa	pampa	PROPN
admet-2	41	26	,	,	PUNCT
admet-2	41	27	is	be	AUX
admet-2	41	28	illustrated	illustrate	VERB
admet-2	41	29	in	in	ADP
admet-2	41	30	a	a	DET
admet-2	41	31	broad	broad	ADJ
admet-2	41	32	sense	sense	NOUN
admet-2	41	33	(	(	PUNCT
admet-2	41	34	chapter	chapter	NOUN
admet-2	41	35	7	7	NUM
admet-2	41	36	)	)	PUNCT
admet-2	41	37	.	.	PUNCT
admet-2	42	1	cell	cell	NOUN
admet-2	42	2	-	-	PUNCT
admet-2	42	3	based	base	VERB
admet-2	42	4	assays	assay	NOUN
admet-2	42	5	,	,	PUNCT
admet-2	42	6	caco-2	caco-2	NUM
admet-2	42	7	and	and	CCONJ
admet-2	42	8	mdck	mdck	PROPN
admet-2	42	9	are	be	AUX
admet-2	42	10	explored	explore	VERB
admet-2	42	11	in	in	ADP
admet-2	42	12	chapter	chapter	NOUN
admet-2	42	13	8	8	NUM
admet-2	42	14	.	.	PUNCT
admet-2	43	1	the	the	DET
admet-2	43	2	idea	idea	NOUN
admet-2	43	3	is	be	AUX
admet-2	43	4	to	to	PART
admet-2	43	5	develop	develop	VERB
admet-2	43	6	protocols	protocol	NOUN
admet-2	43	7	and	and	CCONJ
admet-2	43	8	advanced	advanced	ADJ
admet-2	43	9	data	datum	NOUN
admet-2	43	10	analysis	analysis	NOUN
admet-2	43	11	for	for	ADP
admet-2	43	12	inter	inter	ADJ
admet-2	43	13	-	-	ADJ
admet-2	43	14	laboratory	laboratory	ADJ
admet-2	43	15	cell	cell	NOUN
admet-2	43	16	-	-	PUNCT
admet-2	43	17	based	base	VERB
admet-2	43	18	transport	transport	NOUN
admet-2	43	19	studies	study	NOUN
admet-2	43	20	.	.	PUNCT
admet-2	44	1	finally	finally	ADV
admet-2	44	2	,	,	PUNCT
admet-2	44	3	fundamental	fundamental	ADJ
admet-2	44	4	concepts	concept	NOUN
admet-2	44	5	of	of	ADP
admet-2	44	6	permeability	permeability	NOUN
admet-2	44	7	measurements	measurement	NOUN
admet-2	44	8	using	use	VERB
admet-2	44	9	endothelial	endothelial	ADJ
admet-2	44	10	cell	cell	NOUN
admet-2	44	11	models	model	NOUN
admet-2	44	12	of	of	ADP
admet-2	44	13	the	the	DET
admet-2	44	14	blood	blood	NOUN
admet-2	44	15	–	–	PUNCT
admet-2	44	16	brain	brain	NOUN
admet-2	44	17	barrier	barrier	NOUN
admet-2	44	18	are	be	AUX
admet-2	44	19	covered	cover	VERB
admet-2	44	20	in	in	ADP
admet-2	44	21	chapter	chapter	NOUN
admet-2	44	22	9	9	NUM
admet-2	44	23	.	.	PUNCT
admet-2	45	1	throughout	throughout	ADP
admet-2	45	2	the	the	DET
admet-2	45	3	book	book	NOUN
admet-2	45	4	the	the	DET
admet-2	45	5	rules	rule	NOUN
admet-2	45	6	and	and	CCONJ
admet-2	45	7	laws	law	NOUN
admet-2	45	8	of	of	ADP
admet-2	45	9	physical	physical	ADJ
admet-2	45	10	chemistry	chemistry	NOUN
admet-2	45	11	are	be	AUX
admet-2	45	12	followed	follow	VERB
admet-2	45	13	.	.	PUNCT
admet-2	46	1	they	they	PRON
admet-2	46	2	are	be	AUX
admet-2	46	3	explained	explain	VERB
admet-2	46	4	in	in	ADP
admet-2	46	5	a	a	DET
admet-2	46	6	simple	simple	ADJ
admet-2	46	7	way	way	NOUN
admet-2	46	8	but	but	CCONJ
admet-2	46	9	with	with	ADP
admet-2	46	10	sufficient	sufficient	ADJ
admet-2	46	11	detail	detail	NOUN
admet-2	46	12	for	for	SCONJ
admet-2	46	13	readers	reader	NOUN
admet-2	46	14	to	to	PART
admet-2	46	15	gain	gain	VERB
admet-2	46	16	a	a	DET
admet-2	46	17	complete	complete	ADJ
admet-2	46	18	insight	insight	NOUN
admet-2	46	19	into	into	ADP
admet-2	46	20	the	the	DET
admet-2	46	21	topics	topic	NOUN
admet-2	46	22	.	.	PUNCT
admet-2	47	1	furthermore	furthermore	ADV
admet-2	47	2	,	,	PUNCT
admet-2	47	3	this	this	DET
admet-2	47	4	book	book	NOUN
admet-2	47	5	gathers	gather	VERB
admet-2	47	6	together	together	ADV
admet-2	47	7	a	a	DET
admet-2	47	8	huge	huge	ADJ
admet-2	47	9	collection	collection	NOUN
admet-2	47	10	of	of	ADP
admet-2	47	11	relevant	relevant	ADJ
admet-2	47	12	physico	physico	NOUN
admet-2	47	13	-	-	PUNCT
admet-2	47	14	chemical	chemical	NOUN
admet-2	47	15	parameters	parameter	NOUN
admet-2	47	16	determined	determine	VERB
admet-2	47	17	by	by	ADP
admet-2	47	18	the	the	DET
admet-2	47	19	author	author	NOUN
admet-2	47	20	and	and	CCONJ
admet-2	47	21	his	his	PRON
admet-2	47	22	co	co	NOUN
admet-2	47	23	-	-	NOUN
admet-2	47	24	workers	worker	NOUN
admet-2	47	25	or	or	CCONJ
admet-2	47	26	found	find	VERB
admet-2	47	27	in	in	ADP
admet-2	47	28	other	other	ADJ
admet-2	47	29	literature	literature	NOUN
admet-2	47	30	.	.	PUNCT
admet-2	48	1	more	more	ADJ
admet-2	48	2	than	than	ADP
admet-2	48	3	900	900	NUM
admet-2	48	4	pka	pka	NOUN
admet-2	48	5	values	value	NOUN
admet-2	48	6	,	,	PUNCT
admet-2	48	7	350	350	NUM
admet-2	48	8	octanol	octanol	NOUN
admet-2	48	9	/	/	SYM
admet-2	48	10	water	water	NOUN
admet-2	48	11	partition	partition	NOUN
admet-2	48	12	coefficients	coefficient	NOUN
admet-2	48	13	,	,	PUNCT
admet-2	48	14	100	100	NUM
admet-2	48	15	liposome	liposome	NOUN
admet-2	48	16	/	/	SYM
admet-2	48	17	water	water	NOUN
admet-2	48	18	partition	partition	NOUN
admet-2	48	19	coefficients	coefficient	NOUN
admet-2	48	20	,	,	PUNCT
admet-2	48	21	60	60	NUM
admet-2	48	22	solubility	solubility	NOUN
admet-2	48	23	constants	constant	NOUN
admet-2	48	24	,	,	PUNCT
admet-2	48	25	300	300	NUM
admet-2	48	26	permeability	permeability	NOUN
admet-2	48	27	coefficients	coefficient	NOUN
admet-2	48	28	,	,	PUNCT
admet-2	48	29	and	and	CCONJ
admet-2	48	30	almost	almost	ADV
admet-2	48	31	700	700	NUM
admet-2	48	32	caco-2	caco-2	NUM
admet-2	48	33	/	/	SYM
admet-2	48	34	mdck	mdck	NOUN
admet-2	48	35	permeability	permeability	NOUN
admet-2	48	36	coefficients	coefficient	NOUN
admet-2	48	37	as	as	ADV
admet-2	48	38	well	well	ADV
admet-2	48	39	as	as	ADP
admet-2	48	40	200	200	NUM
admet-2	48	41	permeability	permeability	NOUN
admet-2	48	42	values	value	NOUN
admet-2	48	43	related	relate	VERB
admet-2	48	44	to	to	ADP
admet-2	48	45	the	the	DET
admet-2	48	46	blood	blood	NOUN
admet-2	48	47	–	–	PUNCT
admet-2	48	48	brain	brain	NOUN
admet-2	48	49	barrier	barrier	NOUN
admet-2	48	50	can	can	AUX
admet-2	48	51	be	be	AUX
admet-2	48	52	found	find	VERB
admet-2	48	53	in	in	ADP
admet-2	48	54	addition	addition	NOUN
admet-2	48	55	to	to	ADP
admet-2	48	56	many	many	ADJ
admet-2	48	57	other	other	ADJ
admet-2	48	58	parameters	parameter	NOUN
admet-2	48	59	of	of	ADP
admet-2	48	60	pharmaceutical	pharmaceutical	ADJ
admet-2	48	61	interest	interest	NOUN
admet-2	48	62	.	.	PUNCT
admet-2	49	1	this	this	DET
admet-2	49	2	book	book	NOUN
admet-2	49	3	is	be	AUX
admet-2	49	4	essential	essential	ADJ
admet-2	49	5	literature	literature	NOUN
admet-2	49	6	on	on	ADP
admet-2	49	7	the	the	DET
admet-2	49	8	desk	desk	NOUN
admet-2	49	9	of	of	ADP
admet-2	49	10	the	the	DET
admet-2	49	11	pharmaceutical	pharmaceutical	ADJ
admet-2	49	12	scientist	scientist	NOUN
admet-2	49	13	and	and	CCONJ
admet-2	49	14	is	be	AUX
admet-2	49	15	highly	highly	ADV
admet-2	49	16	recommended	recommend	VERB
admet-2	49	17	to	to	ADP
admet-2	49	18	students	student	NOUN
admet-2	49	19	and	and	CCONJ
admet-2	49	20	others	other	NOUN
admet-2	49	21	interested	interested	ADJ
admet-2	49	22	in	in	ADP
admet-2	49	23	the	the	DET
admet-2	49	24	topic	topic	NOUN
admet-2	49	25	of	of	ADP
admet-2	49	26	drug	drug	NOUN
admet-2	49	27	absorption	absorption	NOUN
admet-2	49	28	.	.	PUNCT
admet-2	50	1	©	©	PROPN
admet-2	50	2	2013	2013	NUM
admet-2	50	3	by	by	ADP
admet-2	50	4	the	the	DET
admet-2	50	5	authors	author	NOUN
admet-2	50	6	;	;	PUNCT
admet-2	50	7	licensee	licensee	PROPN
admet-2	50	8	iapc	iapc	PROPN
admet-2	50	9	,	,	PUNCT
admet-2	50	10	zagreb	zagreb	PROPN
admet-2	50	11	,	,	PUNCT
admet-2	50	12	croatia	croatia	PROPN
admet-2	50	13	.	.	PUNCT
admet-2	51	1	this	this	DET
admet-2	51	2	article	article	NOUN
admet-2	51	3	is	be	AUX
admet-2	51	4	an	an	DET
admet-2	51	5	open	open	ADJ
admet-2	51	6	-	-	PUNCT
admet-2	51	7	access	access	NOUN
admet-2	51	8	article	article	NOUN
admet-2	51	9	distributed	distribute	VERB
admet-2	51	10	under	under	ADP
admet-2	51	11	the	the	DET
admet-2	51	12	terms	term	NOUN
admet-2	51	13	and	and	CCONJ
admet-2	51	14	conditions	condition	NOUN
admet-2	51	15	of	of	ADP
admet-2	51	16	the	the	DET
admet-2	51	17	creative	creative	ADJ
admet-2	51	18	commons	common	NOUN
admet-2	51	19	attribution	attribution	NOUN
admet-2	51	20	license	license	NOUN
admet-2	51	21	(	(	PUNCT
admet-2	51	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-2	51	23	)	)	PUNCT
admet-2	51	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-2	51	25	�	�	PROPN