id	sid	tid	token	lemma	pos
admet-2088	1	1	recent	recent	ADJ
admet-2088	1	2	advances	advance	NOUN
admet-2088	1	3	in	in	ADP
admet-2088	1	4	nanomaterial	nanomaterial	NOUN
admet-2088	1	5	-	-	PUNCT
admet-2088	1	6	based	base	VERB
admet-2088	1	7	drug	drug	NOUN
admet-2088	1	8	delivery	delivery	NOUN
admet-2088	1	9	systems	system	NOUN
admet-2088	1	10	for	for	ADP
admet-2088	1	11	melanoma	melanoma	NOUN
admet-2088	1	12	therapy	therapy	NOUN
admet-2088	1	13	doi	doi	NOUN
admet-2088	1	14	:	:	PUNCT
admet-2088	1	15	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	1	16	107	107	NUM
admet-2088	1	17	admet	admet	PROPN
admet-2088	1	18	&	&	CCONJ
admet-2088	1	19	dmpk	dmpk	PROPN
admet-2088	1	20	12(1	12(1	PROPN
admet-2088	1	21	)	)	PUNCT
admet-2088	1	22	(	(	PUNCT
admet-2088	1	23	2024	2024	NUM
admet-2088	1	24	)	)	PUNCT
admet-2088	1	25	107	107	NUM
admet-2088	1	26	-	-	SYM
admet-2088	1	27	150	150	NUM
admet-2088	1	28	;	;	PUNCT
admet-2088	1	29	doi	doi	NOUN
admet-2088	1	30	:	:	PUNCT
admet-2088	1	31	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	1	32	open	open	ADJ
admet-2088	1	33	access	access	NOUN
admet-2088	1	34	:	:	PUNCT
admet-2088	1	35	issn	issn	PROPN
admet-2088	1	36	:	:	PUNCT
admet-2088	1	37	1848	1848	NUM
admet-2088	1	38	-	-	SYM
admet-2088	1	39	7718	7718	NUM
admet-2088	1	40	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-2088	1	41	review	review	VERB
admet-2088	1	42	recent	recent	ADJ
admet-2088	1	43	advances	advance	NOUN
admet-2088	1	44	in	in	ADP
admet-2088	1	45	nanomaterial	nanomaterial	NOUN
admet-2088	1	46	-	-	PUNCT
admet-2088	1	47	based	base	VERB
admet-2088	1	48	drug	drug	NOUN
admet-2088	1	49	delivery	delivery	NOUN
admet-2088	1	50	systems	system	NOUN
admet-2088	1	51	for	for	ADP
admet-2088	1	52	melanoma	melanoma	NOUN
admet-2088	1	53	therapy	therapy	NOUN
admet-2088	1	54	rabinarayan	rabinarayan	PROPN
admet-2088	1	55	parhi1	parhi1	PROPN
admet-2088	1	56	,	,	PUNCT
admet-2088	1	57	*	*	PUNCT
admet-2088	1	58	,	,	PUNCT
admet-2088	1	59	partha	partha	PROPN
admet-2088	1	60	pratim	pratim	PROPN
admet-2088	1	61	kaishap1	kaishap1	NOUN
admet-2088	1	62	and	and	CCONJ
admet-2088	1	63	goutam	goutam	VERB
admet-2088	1	64	kumar	kumar	PROPN
admet-2088	1	65	jena2	jena2	PROPN
admet-2088	1	66	1department	1department	NUM
admet-2088	1	67	of	of	ADP
admet-2088	1	68	pharmaceutical	pharmaceutical	ADJ
admet-2088	1	69	sciences	science	NOUN
admet-2088	1	70	,	,	PUNCT
admet-2088	1	71	susruta	susruta	ADJ
admet-2088	1	72	school	school	NOUN
admet-2088	1	73	of	of	ADP
admet-2088	1	74	medical	medical	ADJ
admet-2088	1	75	and	and	CCONJ
admet-2088	1	76	paramedical	paramedical	ADJ
admet-2088	1	77	sciences	science	NOUN
admet-2088	1	78	,	,	PUNCT
admet-2088	1	79	assam	assam	PROPN
admet-2088	1	80	university	university	PROPN
admet-2088	1	81	(	(	PUNCT
admet-2088	1	82	a	a	DET
admet-2088	1	83	central	central	ADJ
admet-2088	1	84	university	university	NOUN
admet-2088	1	85	)	)	PUNCT
admet-2088	1	86	,	,	PUNCT
admet-2088	1	87	silchar-788011	silchar-788011	PROPN
admet-2088	1	88	,	,	PUNCT
admet-2088	1	89	assam	assam	PROPN
admet-2088	1	90	,	,	PUNCT
admet-2088	1	91	india	india	PROPN
admet-2088	1	92	2roland	2roland	NUM
admet-2088	1	93	institute	institute	PROPN
admet-2088	1	94	of	of	ADP
admet-2088	1	95	pharmaceutical	pharmaceutical	NOUN
admet-2088	1	96	sciences	science	NOUN
admet-2088	1	97	,	,	PUNCT
admet-2088	1	98	berhampur-7600010	berhampur-7600010	NOUN
admet-2088	1	99	,	,	PUNCT
admet-2088	1	100	odisha	odisha	PROPN
admet-2088	1	101	,	,	PUNCT
admet-2088	1	102	india	india	PROPN
admet-2088	1	103	*	*	PUNCT
admet-2088	1	104	corresponding	correspond	VERB
admet-2088	1	105	author	author	NOUN
admet-2088	1	106	:	:	PUNCT
admet-2088	1	107	e	e	NOUN
admet-2088	1	108	-	-	NOUN
admet-2088	1	109	mail	mail	NOUN
admet-2088	1	110	:	:	PUNCT
admet-2088	1	111	rabi59bls623@gmail.com	rabi59bls623@gmail.com	X
admet-2088	1	112	received	receive	VERB
admet-2088	1	113	:	:	PUNCT
admet-2088	1	114	september	september	PROPN
admet-2088	1	115	15	15	NUM
admet-2088	1	116	,	,	PUNCT
admet-2088	1	117	2023	2023	NUM
admet-2088	1	118	;	;	PUNCT
admet-2088	1	119	revised	revise	VERB
admet-2088	1	120	:	:	PUNCT
admet-2088	1	121	october	october	PROPN
admet-2088	1	122	22	22	NUM
admet-2088	1	123	,	,	PUNCT
admet-2088	1	124	2023	2023	NUM
admet-2088	1	125	;	;	PUNCT
admet-2088	1	126	published	publish	VERB
admet-2088	1	127	:	:	PUNCT
admet-2088	1	128	october	october	PROPN
admet-2088	1	129	24	24	NUM
admet-2088	1	130	,	,	PUNCT
admet-2088	1	131	2023	2023	NUM
admet-2088	1	132	abstract	abstract	ADJ
admet-2088	1	133	background	background	NOUN
admet-2088	1	134	and	and	CCONJ
admet-2088	1	135	purpose	purpose	NOUN
admet-2088	1	136	:	:	PUNCT
admet-2088	1	137	safe	safe	ADJ
admet-2088	1	138	and	and	CCONJ
admet-2088	1	139	effective	effective	ADJ
admet-2088	1	140	drug	drug	NOUN
admet-2088	1	141	delivery	delivery	NOUN
admet-2088	1	142	is	be	AUX
admet-2088	1	143	crucial	crucial	ADJ
admet-2088	1	144	for	for	ADP
admet-2088	1	145	the	the	DET
admet-2088	1	146	treatment	treatment	NOUN
admet-2088	1	147	of	of	ADP
admet-2088	1	148	cancer	cancer	NOUN
admet-2088	1	149	,	,	PUNCT
admet-2088	1	150	which	which	PRON
admet-2088	1	151	is	be	AUX
admet-2088	1	152	quite	quite	ADV
admet-2088	1	153	impossible	impossible	ADJ
admet-2088	1	154	to	to	PART
admet-2088	1	155	achieve	achieve	VERB
admet-2088	1	156	through	through	ADP
admet-2088	1	157	traditional	traditional	ADJ
admet-2088	1	158	methods	method	NOUN
admet-2088	1	159	.	.	PUNCT
admet-2088	2	1	among	among	ADP
admet-2088	2	2	all	all	DET
admet-2088	2	3	types	type	NOUN
admet-2088	2	4	of	of	ADP
admet-2088	2	5	cancer	cancer	NOUN
admet-2088	2	6	,	,	PUNCT
admet-2088	2	7	skin	skin	NOUN
admet-2088	2	8	melanoma	melanoma	NOUN
admet-2088	2	9	is	be	AUX
admet-2088	2	10	known	know	VERB
admet-2088	2	11	for	for	ADP
admet-2088	2	12	its	its	PRON
admet-2088	2	13	aggressive	aggressive	ADJ
admet-2088	2	14	metastasizing	metastasizing	NOUN
admet-2088	2	15	ability	ability	NOUN
admet-2088	2	16	and	and	CCONJ
admet-2088	2	17	an	an	DET
admet-2088	2	18	unprecedented	unprecedented	ADJ
admet-2088	2	19	higher	high	ADJ
admet-2088	2	20	degree	degree	NOUN
admet-2088	2	21	of	of	ADP
admet-2088	2	22	lethalness	lethalness	NOUN
admet-2088	2	23	,	,	PUNCT
admet-2088	2	24	limiting	limit	VERB
admet-2088	2	25	the	the	DET
admet-2088	2	26	overall	overall	ADJ
admet-2088	2	27	therapeutic	therapeutic	ADJ
admet-2088	2	28	efficacy	efficacy	NOUN
admet-2088	2	29	.	.	PUNCT
admet-2088	3	1	here	here	ADV
admet-2088	3	2	,	,	PUNCT
admet-2088	3	3	we	we	PRON
admet-2088	3	4	focus	focus	VERB
admet-2088	3	5	on	on	ADP
admet-2088	3	6	the	the	DET
admet-2088	3	7	different	different	ADJ
admet-2088	3	8	types	type	NOUN
admet-2088	3	9	of	of	ADP
admet-2088	3	10	nanomaterials	nanomaterial	NOUN
admet-2088	3	11	(	(	PUNCT
admet-2088	3	12	nms	nms	NOUN
admet-2088	3	13	)	)	PUNCT
admet-2088	3	14	and	and	CCONJ
admet-2088	3	15	their	their	PRON
admet-2088	3	16	drug	drug	NOUN
admet-2088	3	17	delivery	delivery	NOUN
admet-2088	3	18	applications	application	NOUN
admet-2088	3	19	against	against	ADP
admet-2088	3	20	melanoma	melanoma	NOUN
admet-2088	3	21	.	.	PUNCT
admet-2088	4	1	experimental	experimental	ADJ
admet-2088	4	2	approach	approach	NOUN
admet-2088	4	3	:	:	PUNCT
admet-2088	4	4	all	all	DET
admet-2088	4	5	relevant	relevant	ADJ
admet-2088	4	6	publications	publication	NOUN
admet-2088	4	7	,	,	PUNCT
admet-2088	4	8	including	include	VERB
admet-2088	4	9	research	research	NOUN
admet-2088	4	10	papers	paper	NOUN
admet-2088	4	11	,	,	PUNCT
admet-2088	4	12	reviews	review	NOUN
admet-2088	4	13	,	,	PUNCT
admet-2088	4	14	chapters	chapter	NOUN
admet-2088	4	15	and	and	CCONJ
admet-2088	4	16	patents	patent	NOUN
admet-2088	4	17	,	,	PUNCT
admet-2088	4	18	were	be	AUX
admet-2088	4	19	assessed	assess	VERB
admet-2088	4	20	using	use	VERB
admet-2088	4	21	search	search	NOUN
admet-2088	4	22	engines	engine	NOUN
admet-2088	4	23	such	such	ADJ
admet-2088	4	24	as	as	ADP
admet-2088	4	25	scopus	scopus	NOUN
admet-2088	4	26	and	and	CCONJ
admet-2088	4	27	pubmed	pubmed	PROPN
admet-2088	4	28	,	,	PUNCT
admet-2088	4	29	up	up	ADP
admet-2088	4	30	to	to	ADP
admet-2088	4	31	the	the	DET
admet-2088	4	32	end	end	NOUN
admet-2088	4	33	of	of	ADP
admet-2088	4	34	august	august	PROPN
admet-2088	4	35	of	of	ADP
admet-2088	4	36	2023	2023	NUM
admet-2088	4	37	.	.	PUNCT
admet-2088	5	1	the	the	DET
admet-2088	5	2	keywords	keyword	NOUN
admet-2088	5	3	used	use	VERB
admet-2088	5	4	in	in	ADP
admet-2088	5	5	the	the	DET
admet-2088	5	6	search	search	NOUN
admet-2088	5	7	were	be	AUX
admet-2088	5	8	:	:	PUNCT
admet-2088	5	9	nanomaterials	nanomaterial	NOUN
admet-2088	5	10	,	,	PUNCT
admet-2088	5	11	melanoma	melanoma	NOUN
admet-2088	5	12	,	,	PUNCT
admet-2088	5	13	drug	drug	NOUN
admet-2088	5	14	delivery	delivery	NOUN
admet-2088	5	15	routes	route	NOUN
admet-2088	5	16	for	for	ADP
admet-2088	5	17	melanoma	melanoma	NOUN
admet-2088	5	18	,	,	PUNCT
admet-2088	5	19	and	and	CCONJ
admet-2088	5	20	nanomaterial	nanomaterial	NOUN
admet-2088	5	21	-	-	PUNCT
admet-2088	5	22	based	base	VERB
admet-2088	5	23	drug	drug	NOUN
admet-2088	5	24	delivery	delivery	NOUN
admet-2088	5	25	systems	system	NOUN
admet-2088	5	26	(	(	PUNCT
admet-2088	5	27	dds	dds	PROPN
admet-2088	5	28	)	)	PUNCT
admet-2088	5	29	.	.	PUNCT
admet-2088	6	1	most	most	ADJ
admet-2088	6	2	of	of	ADP
admet-2088	6	3	the	the	DET
admet-2088	6	4	publications	publication	NOUN
admet-2088	6	5	out	out	ADP
admet-2088	6	6	of	of	ADP
admet-2088	6	7	234	234	NUM
admet-2088	6	8	cited	cite	VERB
admet-2088	6	9	in	in	ADP
admet-2088	6	10	this	this	DET
admet-2088	6	11	review	review	NOUN
admet-2088	6	12	are	be	AUX
admet-2088	6	13	from	from	ADP
admet-2088	6	14	the	the	DET
admet-2088	6	15	last	last	ADJ
admet-2088	6	16	five	five	NUM
admet-2088	6	17	years	year	NOUN
admet-2088	6	18	.	.	PUNCT
admet-2088	7	1	key	key	ADJ
admet-2088	7	2	results	result	NOUN
admet-2088	7	3	:	:	PUNCT
admet-2088	7	4	the	the	DET
admet-2088	7	5	recent	recent	ADJ
admet-2088	7	6	advancement	advancement	NOUN
admet-2088	7	7	and	and	CCONJ
admet-2088	7	8	mechanism	mechanism	NOUN
admet-2088	7	9	of	of	ADP
admet-2088	7	10	action	action	NOUN
admet-2088	7	11	of	of	ADP
admet-2088	7	12	various	various	ADJ
admet-2088	7	13	nms	nms	NOUN
admet-2088	7	14	against	against	ADP
admet-2088	7	15	melanoma	melanoma	NOUN
admet-2088	7	16	,	,	PUNCT
admet-2088	7	17	including	include	VERB
admet-2088	7	18	inorganic	inorganic	ADJ
admet-2088	7	19	metallic	metallic	ADJ
admet-2088	7	20	and	and	CCONJ
admet-2088	7	21	carbon	carbon	NOUN
admet-2088	7	22	-	-	PUNCT
admet-2088	7	23	based	base	VERB
admet-2088	7	24	nms	nms	NOUN
admet-2088	7	25	,	,	PUNCT
admet-2088	7	26	organic	organic	ADJ
admet-2088	7	27	polymeric	polymeric	NOUN
admet-2088	7	28	and	and	CCONJ
admet-2088	7	29	lipid	lipid	NOUN
admet-2088	7	30	-	-	PUNCT
admet-2088	7	31	based	base	VERB
admet-2088	7	32	nms	nms	NOUN
admet-2088	7	33	,	,	PUNCT
admet-2088	7	34	and	and	CCONJ
admet-2088	7	35	cell	cell	NOUN
admet-2088	7	36	-	-	PUNCT
admet-2088	7	37	derived	derive	VERB
admet-2088	7	38	vesicles	vesicle	NOUN
admet-2088	7	39	are	be	AUX
admet-2088	7	40	discussed	discuss	VERB
admet-2088	7	41	.	.	PUNCT
admet-2088	8	1	we	we	PRON
admet-2088	8	2	also	also	ADV
admet-2088	8	3	focus	focus	VERB
admet-2088	8	4	on	on	ADP
admet-2088	8	5	the	the	DET
admet-2088	8	6	application	application	NOUN
admet-2088	8	7	of	of	ADP
admet-2088	8	8	different	different	ADJ
admet-2088	8	9	nms	nms	NOUN
admet-2088	8	10	in	in	ADP
admet-2088	8	11	the	the	DET
admet-2088	8	12	delivery	delivery	NOUN
admet-2088	8	13	of	of	ADP
admet-2088	8	14	therapeutic	therapeutic	ADJ
admet-2088	8	15	agents	agent	NOUN
admet-2088	8	16	for	for	ADP
admet-2088	8	17	melanoma	melanoma	NOUN
admet-2088	8	18	therapy	therapy	NOUN
admet-2088	8	19	.	.	PUNCT
admet-2088	9	1	in	in	ADP
admet-2088	9	2	addition	addition	NOUN
admet-2088	9	3	,	,	PUNCT
admet-2088	9	4	the	the	DET
admet-2088	9	5	skin	skin	NOUN
admet-2088	9	6	and	and	CCONJ
admet-2088	9	7	melanoma	melanoma	NOUN
admet-2088	9	8	,	,	PUNCT
admet-2088	9	9	genetic	genetic	ADJ
admet-2088	9	10	mutation	mutation	NOUN
admet-2088	9	11	and	and	CCONJ
admet-2088	9	12	pathways	pathway	NOUN
admet-2088	9	13	for	for	ADP
admet-2088	9	14	melanoma	melanoma	NOUN
admet-2088	9	15	,	,	PUNCT
admet-2088	9	16	conventional	conventional	ADJ
admet-2088	9	17	treatment	treatment	NOUN
admet-2088	9	18	options	option	NOUN
admet-2088	9	19	,	,	PUNCT
admet-2088	9	20	and	and	CCONJ
admet-2088	9	21	delivery	delivery	NOUN
admet-2088	9	22	routes	route	NOUN
admet-2088	9	23	for	for	ADP
admet-2088	9	24	therapeutic	therapeutic	ADJ
admet-2088	9	25	agents	agent	NOUN
admet-2088	9	26	are	be	AUX
admet-2088	9	27	also	also	ADV
admet-2088	9	28	discussed	discuss	VERB
admet-2088	9	29	briefly	briefly	ADV
admet-2088	9	30	.	.	PUNCT
admet-2088	10	1	conclusion	conclusion	NOUN
admet-2088	10	2	:	:	PUNCT
admet-2088	10	3	there	there	PRON
admet-2088	10	4	are	be	VERB
admet-2088	10	5	few	few	ADJ
admet-2088	10	6	nm	nm	ADV
admet-2088	10	7	-	-	PUNCT
admet-2088	10	8	based	base	VERB
admet-2088	10	9	dds	dds	PROPN
admet-2088	10	10	developed	develop	VERB
admet-2088	10	11	in	in	ADP
admet-2088	10	12	the	the	DET
admet-2088	10	13	lab	lab	NOUN
admet-2088	10	14	set	set	VERB
admet-2088	10	15	up	up	ADP
admet-2088	10	16	recently	recently	ADV
admet-2088	10	17	.	.	PUNCT
admet-2088	11	1	the	the	DET
admet-2088	11	2	findings	finding	NOUN
admet-2088	11	3	of	of	ADP
admet-2088	11	4	this	this	DET
admet-2088	11	5	review	review	NOUN
admet-2088	11	6	will	will	AUX
admet-2088	11	7	pave	pave	VERB
admet-2088	11	8	the	the	DET
admet-2088	11	9	path	path	NOUN
admet-2088	11	10	for	for	ADP
admet-2088	11	11	the	the	DET
admet-2088	11	12	development	development	NOUN
admet-2088	11	13	of	of	ADP
admet-2088	11	14	nm	nm	ADV
admet-2088	11	15	-	-	PUNCT
admet-2088	11	16	based	base	VERB
admet-2088	11	17	dds	dds	PROPN
admet-2088	11	18	on	on	ADP
admet-2088	11	19	an	an	DET
admet-2088	11	20	industrial	industrial	ADJ
admet-2088	11	21	scale	scale	NOUN
admet-2088	11	22	and	and	CCONJ
admet-2088	11	23	help	help	NOUN
admet-2088	11	24	in	in	ADP
admet-2088	11	25	the	the	DET
admet-2088	11	26	better	well	ADJ
admet-2088	11	27	management	management	NOUN
admet-2088	11	28	of	of	ADP
admet-2088	11	29	skin	skin	NOUN
admet-2088	11	30	melanoma	melanoma	NOUN
admet-2088	11	31	.	.	PUNCT
admet-2088	12	1	©	©	NOUN
admet-2088	12	2	2023	2023	NUM
admet-2088	12	3	by	by	ADP
admet-2088	12	4	the	the	DET
admet-2088	12	5	authors	author	NOUN
admet-2088	12	6	.	.	PUNCT
admet-2088	13	1	this	this	DET
admet-2088	13	2	article	article	NOUN
admet-2088	13	3	is	be	AUX
admet-2088	13	4	an	an	DET
admet-2088	13	5	open	open	ADJ
admet-2088	13	6	-	-	PUNCT
admet-2088	13	7	access	access	NOUN
admet-2088	13	8	article	article	NOUN
admet-2088	13	9	distributed	distribute	VERB
admet-2088	13	10	under	under	ADP
admet-2088	13	11	the	the	DET
admet-2088	13	12	terms	term	NOUN
admet-2088	13	13	and	and	CCONJ
admet-2088	13	14	conditions	condition	NOUN
admet-2088	13	15	of	of	ADP
admet-2088	13	16	the	the	DET
admet-2088	13	17	creative	creative	ADJ
admet-2088	13	18	commons	common	NOUN
admet-2088	13	19	attribution	attribution	NOUN
admet-2088	13	20	license	license	NOUN
admet-2088	13	21	(	(	PUNCT
admet-2088	13	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2088	13	23	)	)	PUNCT
admet-2088	13	24	.	.	PUNCT
admet-2088	14	1	keywords	keyword	VERB
admet-2088	14	2	cancer	cancer	NOUN
admet-2088	14	3	;	;	PUNCT
admet-2088	14	4	nanoparticles	nanoparticle	NOUN
admet-2088	14	5	;	;	PUNCT
admet-2088	14	6	carbon	carbon	NOUN
admet-2088	14	7	nanotubes	nanotube	NOUN
admet-2088	14	8	;	;	PUNCT
admet-2088	14	9	genetic	genetic	ADJ
admet-2088	14	10	mutation	mutation	NOUN
admet-2088	14	11	;	;	PUNCT
admet-2088	14	12	radiation	radiation	NOUN
admet-2088	14	13	therapy	therapy	NOUN
admet-2088	14	14	,	,	PUNCT
admet-2088	14	15	targeted	target	VERB
admet-2088	14	16	therapy	therapy	NOUN
admet-2088	14	17	introduction	introduction	NOUN
admet-2088	14	18	cancer	cancer	NOUN
admet-2088	14	19	is	be	AUX
admet-2088	14	20	one	one	NUM
admet-2088	14	21	of	of	ADP
admet-2088	14	22	the	the	DET
admet-2088	14	23	most	most	ADV
admet-2088	14	24	dreadful	dreadful	ADJ
admet-2088	14	25	diseases	disease	NOUN
admet-2088	14	26	with	with	ADP
admet-2088	14	27	a	a	DET
admet-2088	14	28	serious	serious	ADJ
admet-2088	14	29	impact	impact	NOUN
admet-2088	14	30	worldwide	worldwide	ADV
admet-2088	14	31	.	.	PUNCT
admet-2088	15	1	it	it	PRON
admet-2088	15	2	is	be	AUX
admet-2088	15	3	characterised	characterise	VERB
admet-2088	15	4	by	by	ADP
admet-2088	15	5	uncontrolled	uncontrolled	ADJ
admet-2088	15	6	growth	growth	NOUN
admet-2088	15	7	and	and	CCONJ
admet-2088	15	8	proliferation	proliferation	NOUN
admet-2088	15	9	of	of	ADP
admet-2088	15	10	cells	cell	NOUN
admet-2088	15	11	and	and	CCONJ
admet-2088	15	12	is	be	AUX
admet-2088	15	13	mainly	mainly	ADV
admet-2088	15	14	related	relate	VERB
admet-2088	15	15	to	to	ADP
admet-2088	15	16	changing	change	VERB
admet-2088	15	17	nutrition	nutrition	NOUN
admet-2088	15	18	and	and	CCONJ
admet-2088	15	19	lifestyle	lifestyle	NOUN
admet-2088	16	1	[	[	X
admet-2088	16	2	1	1	NUM
admet-2088	16	3	]	]	PUNCT
admet-2088	16	4	.	.	PUNCT
admet-2088	17	1	this	this	PRON
admet-2088	17	2	is	be	AUX
admet-2088	17	3	clearly	clearly	ADV
admet-2088	17	4	witnessed	witness	VERB
admet-2088	17	5	from	from	ADP
admet-2088	17	6	a	a	DET
admet-2088	17	7	report	report	NOUN
admet-2088	17	8	published	publish	VERB
admet-2088	17	9	by	by	ADP
admet-2088	17	10	the	the	DET
admet-2088	17	11	national	national	PROPN
admet-2088	17	12	cancer	cancer	PROPN
admet-2088	17	13	institute	institute	PROPN
admet-2088	17	14	(	(	PUNCT
admet-2088	17	15	nci	nci	PROPN
admet-2088	17	16	)	)	PUNCT
admet-2088	17	17	that	that	SCONJ
admet-2088	17	18	in	in	ADP
admet-2088	17	19	2016	2016	NUM
admet-2088	17	20	,	,	PUNCT
admet-2088	17	21	about	about	ADP
admet-2088	17	22	1,700,000	1,700,000	NUM
admet-2088	17	23	new	new	ADJ
admet-2088	17	24	cancer	cancer	NOUN
admet-2088	17	25	cases	case	NOUN
admet-2088	17	26	were	be	AUX
admet-2088	17	27	diagnosed	diagnose	VERB
admet-2088	17	28	in	in	ADP
admet-2088	17	29	the	the	DET
admet-2088	17	30	united	united	PROPN
admet-2088	17	31	states	states	PROPN
admet-2088	17	32	,	,	PUNCT
admet-2088	17	33	and	and	CCONJ
admet-2088	17	34	it	it	PRON
admet-2088	17	35	caused	cause	VERB
admet-2088	17	36	the	the	DET
admet-2088	17	37	death	death	NOUN
admet-2088	17	38	of	of	ADP
admet-2088	17	39	595,690	595,690	NUM
admet-2088	17	40	people	people	NOUN
admet-2088	17	41	[	[	X
admet-2088	17	42	2	2	NUM
admet-2088	17	43	]	]	PUNCT
admet-2088	17	44	.	.	PUNCT
admet-2088	18	1	the	the	DET
admet-2088	18	2	high	high	ADJ
admet-2088	18	3	death	death	NOUN
admet-2088	18	4	rate	rate	NOUN
admet-2088	18	5	is	be	AUX
admet-2088	18	6	mainly	mainly	ADV
admet-2088	18	7	because	because	SCONJ
admet-2088	18	8	of	of	ADP
admet-2088	18	9	poor	poor	ADJ
admet-2088	18	10	prognosis	prognosis	NOUN
admet-2088	18	11	for	for	ADP
admet-2088	18	12	many	many	ADJ
admet-2088	18	13	cancer	cancer	NOUN
admet-2088	18	14	types	type	NOUN
admet-2088	18	15	.	.	PUNCT
admet-2088	19	1	the	the	DET
admet-2088	19	2	major	major	ADJ
admet-2088	19	3	factors	factor	NOUN
admet-2088	19	4	contributing	contribute	VERB
admet-2088	19	5	to	to	ADP
admet-2088	19	6	cancers	cancer	NOUN
admet-2088	19	7	are	be	AUX
admet-2088	19	8	carcinogens	carcinogen	NOUN
admet-2088	19	9	,	,	PUNCT
admet-2088	19	10	which	which	PRON
admet-2088	19	11	have	have	VERB
admet-2088	19	12	the	the	DET
admet-2088	19	13	potential	potential	NOUN
admet-2088	19	14	to	to	PART
admet-2088	19	15	cause	cause	VERB
admet-2088	19	16	dysplastic	dysplastic	ADJ
admet-2088	19	17	,	,	PUNCT
admet-2088	19	18	hyperplastic	hyperplastic	ADJ
admet-2088	19	19	or	or	CCONJ
admet-2088	19	20	degenerative	degenerative	ADJ
admet-2088	19	21	alternation	alternation	NOUN
admet-2088	19	22	in	in	ADP
admet-2088	19	23	cell	cell	NOUN
admet-2088	19	24	haemostasis	haemostasis	NOUN
admet-2088	19	25	,	,	PUNCT
admet-2088	19	26	external	external	ADJ
admet-2088	19	27	factors	factor	NOUN
admet-2088	19	28	,	,	PUNCT
admet-2088	19	29	such	such	ADJ
admet-2088	19	30	as	as	ADP
admet-2088	19	31	radiation	radiation	NOUN
admet-2088	19	32	,	,	PUNCT
admet-2088	19	33	pollution	pollution	NOUN
admet-2088	19	34	and	and	CCONJ
admet-2088	19	35	internal	internal	ADJ
admet-2088	19	36	factors	factor	NOUN
admet-2088	19	37	,	,	PUNCT
admet-2088	19	38	including	include	VERB
admet-2088	19	39	oxidative	oxidative	ADJ
admet-2088	19	40	stress	stress	NOUN
admet-2088	19	41	[	[	X
admet-2088	19	42	3,4	3,4	NUM
admet-2088	19	43	]	]	PUNCT
admet-2088	19	44	.	.	PUNCT
admet-2088	20	1	cancers	cancer	NOUN
admet-2088	20	2	are	be	AUX
admet-2088	20	3	classified	classify	VERB
admet-2088	20	4	either	either	CCONJ
admet-2088	20	5	by	by	ADP
admet-2088	20	6	their	their	PRON
admet-2088	20	7	location	location	NOUN
admet-2088	20	8	,	,	PUNCT
admet-2088	20	9	such	such	ADJ
admet-2088	20	10	as	as	ADP
admet-2088	20	11	liver	liver	NOUN
admet-2088	20	12	,	,	PUNCT
admet-2088	20	13	brain	brain	NOUN
admet-2088	20	14	,	,	PUNCT
admet-2088	20	15	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	20	16	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	20	17	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-2088	21	1	mailto:rabi59bls623@gmail.com	mailto:rabi59bls623@gmail.com	X
admet-2088	21	2	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2088	21	3	m.	m.	PROPN
admet-2088	21	4	kulkarni	kulkarni	PROPN
admet-2088	21	5	et	et	PROPN
admet-2088	21	6	al	al	PROPN
admet-2088	21	7	.	.	PROPN
admet-2088	21	8	admet	admet	PROPN
admet-2088	21	9	&	&	CCONJ
admet-2088	21	10	dmpk	dmpk	PROPN
admet-2088	21	11	12(1	12(1	PROPN
admet-2088	21	12	)	)	PUNCT
admet-2088	21	13	(	(	PUNCT
admet-2088	21	14	2024	2024	NUM
admet-2088	21	15	)	)	PUNCT
admet-2088	21	16	107	107	NUM
admet-2088	21	17	-	-	SYM
admet-2088	21	18	150	150	NUM
admet-2088	21	19	108	108	NUM
admet-2088	21	20	lung	lung	NOUN
admet-2088	21	21	,	,	PUNCT
admet-2088	21	22	breast	breast	NOUN
admet-2088	21	23	,	,	PUNCT
admet-2088	21	24	oral	oral	ADJ
admet-2088	21	25	,	,	PUNCT
admet-2088	21	26	skin	skin	NOUN
admet-2088	21	27	,	,	PUNCT
admet-2088	21	28	intestinal	intestinal	ADJ
admet-2088	21	29	,	,	PUNCT
admet-2088	21	30	etc	etc	X
admet-2088	21	31	.	.	X
admet-2088	21	32	,	,	PUNCT
admet-2088	21	33	or	or	CCONJ
admet-2088	21	34	by	by	ADP
admet-2088	21	35	their	their	PRON
admet-2088	21	36	histological	histological	ADJ
admet-2088	21	37	characteristics	characteristic	NOUN
admet-2088	21	38	,	,	PUNCT
admet-2088	21	39	including	include	VERB
admet-2088	21	40	sarcoma	sarcoma	NOUN
admet-2088	21	41	on	on	ADP
admet-2088	21	42	connective	connective	ADJ
admet-2088	21	43	and	and	CCONJ
admet-2088	21	44	supportive	supportive	ADJ
admet-2088	21	45	tissues	tissue	NOUN
admet-2088	21	46	,	,	PUNCT
admet-2088	21	47	melanoma	melanoma	NOUN
admet-2088	21	48	on	on	ADP
admet-2088	21	49	the	the	DET
admet-2088	21	50	skin	skin	NOUN
admet-2088	21	51	,	,	PUNCT
admet-2088	21	52	carcinoma	carcinoma	NOUN
admet-2088	21	53	on	on	ADP
admet-2088	21	54	epithelial	epithelial	ADJ
admet-2088	21	55	tissues	tissue	NOUN
admet-2088	21	56	,	,	PUNCT
admet-2088	21	57	myeloma	myeloma	NOUN
admet-2088	21	58	on	on	ADP
admet-2088	21	59	bone	bone	NOUN
admet-2088	21	60	marrow	marrow	NOUN
admet-2088	21	61	,	,	PUNCT
admet-2088	21	62	lymphoma	lymphoma	NOUN
admet-2088	21	63	on	on	ADP
admet-2088	21	64	lymphatic	lymphatic	ADJ
admet-2088	21	65	systems	system	NOUN
admet-2088	21	66	etc	etc	X
admet-2088	21	67	.	.	PUNCT
admet-2088	22	1	[	[	X
admet-2088	22	2	5	5	NUM
admet-2088	22	3	]	]	PUNCT
admet-2088	22	4	.	.	PUNCT
admet-2088	23	1	melanoma	melanoma	PROPN
admet-2088	23	2	is	be	AUX
admet-2088	23	3	a	a	DET
admet-2088	23	4	highly	highly	ADV
admet-2088	23	5	aggressive	aggressive	ADJ
admet-2088	23	6	form	form	NOUN
admet-2088	23	7	of	of	ADP
admet-2088	23	8	skin	skin	NOUN
admet-2088	23	9	cancer	cancer	NOUN
admet-2088	23	10	and	and	CCONJ
admet-2088	23	11	a	a	DET
admet-2088	23	12	prime	prime	ADJ
admet-2088	23	13	global	global	ADJ
admet-2088	23	14	health	health	NOUN
admet-2088	23	15	concern	concern	NOUN
admet-2088	23	16	due	due	ADP
admet-2088	23	17	to	to	ADP
admet-2088	23	18	its	its	PRON
admet-2088	23	19	metastasizing	metastasizing	ADJ
admet-2088	23	20	nature	nature	NOUN
admet-2088	23	21	and	and	CCONJ
admet-2088	23	22	higher	high	ADJ
admet-2088	23	23	mortality	mortality	NOUN
admet-2088	23	24	rate	rate	NOUN
admet-2088	23	25	.	.	PUNCT
admet-2088	24	1	there	there	PRON
admet-2088	24	2	is	be	VERB
admet-2088	24	3	a	a	DET
admet-2088	24	4	huge	huge	ADJ
admet-2088	24	5	geographical	geographical	ADJ
admet-2088	24	6	variation	variation	NOUN
admet-2088	24	7	in	in	ADP
admet-2088	24	8	the	the	DET
admet-2088	24	9	occurrence	occurrence	NOUN
admet-2088	24	10	across	across	ADP
admet-2088	24	11	world	world	NOUN
admet-2088	24	12	regions	region	NOUN
admet-2088	24	13	and	and	CCONJ
admet-2088	24	14	countries	country	NOUN
admet-2088	24	15	.	.	PUNCT
admet-2088	25	1	as	as	ADP
admet-2088	25	2	per	per	ADP
admet-2088	25	3	the	the	DET
admet-2088	25	4	most	most	ADV
admet-2088	25	5	recent	recent	ADJ
admet-2088	25	6	epidemiological	epidemiological	ADJ
admet-2088	25	7	assessments	assessment	NOUN
admet-2088	25	8	of	of	ADP
admet-2088	25	9	global	global	ADJ
admet-2088	25	10	cancer	cancer	NOUN
admet-2088	25	11	data	datum	NOUN
admet-2088	25	12	,	,	PUNCT
admet-2088	25	13	the	the	DET
admet-2088	25	14	estimated	estimate	VERB
admet-2088	25	15	number	number	NOUN
admet-2088	25	16	of	of	ADP
admet-2088	25	17	new	new	ADJ
admet-2088	25	18	melanoma	melanoma	NOUN
admet-2088	25	19	cases	case	NOUN
admet-2088	25	20	is	be	AUX
admet-2088	25	21	325,000	325,000	NUM
admet-2088	25	22	,	,	PUNCT
admet-2088	25	23	and	and	CCONJ
admet-2088	25	24	deaths	death	NOUN
admet-2088	25	25	due	due	ADJ
admet-2088	25	26	to	to	ADP
admet-2088	25	27	melanoma	melanoma	PROPN
admet-2088	25	28	reached	reach	VERB
admet-2088	25	29	57,000	57,000	NUM
admet-2088	25	30	in	in	ADP
admet-2088	25	31	2020	2020	NUM
admet-2088	25	32	[	[	X
admet-2088	25	33	6	6	NUM
admet-2088	25	34	]	]	PUNCT
admet-2088	25	35	.	.	PUNCT
admet-2088	26	1	if	if	SCONJ
admet-2088	26	2	this	this	DET
admet-2088	26	3	rate	rate	NOUN
admet-2088	26	4	continues	continue	VERB
admet-2088	26	5	,	,	PUNCT
admet-2088	26	6	the	the	DET
admet-2088	26	7	global	global	ADJ
admet-2088	26	8	burden	burden	NOUN
admet-2088	26	9	from	from	ADP
admet-2088	26	10	melanoma	melanoma	NOUN
admet-2088	26	11	is	be	AUX
admet-2088	26	12	estimated	estimate	VERB
admet-2088	26	13	to	to	PART
admet-2088	26	14	reach	reach	VERB
admet-2088	26	15	a	a	DET
admet-2088	26	16	staggering	staggering	ADJ
admet-2088	26	17	510,000	510,000	NUM
admet-2088	26	18	new	new	ADJ
admet-2088	26	19	cases	case	NOUN
admet-2088	26	20	and	and	CCONJ
admet-2088	26	21	96,000	96,000	NUM
admet-2088	26	22	deaths	death	NOUN
admet-2088	26	23	by	by	ADP
admet-2088	26	24	2040	2040	NUM
admet-2088	27	1	[	[	X
admet-2088	27	2	7	7	NUM
admet-2088	27	3	]	]	PUNCT
admet-2088	27	4	.	.	PUNCT
admet-2088	28	1	the	the	DET
admet-2088	28	2	most	most	ADV
admet-2088	28	3	concerning	concerning	ADJ
admet-2088	28	4	aspect	aspect	NOUN
admet-2088	28	5	of	of	ADP
admet-2088	28	6	melanoma	melanoma	NOUN
admet-2088	28	7	is	be	AUX
admet-2088	28	8	that	that	SCONJ
admet-2088	28	9	there	there	PRON
admet-2088	28	10	is	be	VERB
admet-2088	28	11	a	a	DET
admet-2088	28	12	significant	significant	ADJ
admet-2088	28	13	death	death	NOUN
admet-2088	28	14	of	of	ADP
admet-2088	28	15	individuals	individual	NOUN
admet-2088	28	16	aged	age	VERB
admet-2088	28	17	between	between	ADP
admet-2088	28	18	20	20	NUM
admet-2088	28	19	-	-	SYM
admet-2088	28	20	35	35	NUM
admet-2088	28	21	years	year	NOUN
admet-2088	29	1	[	[	X
admet-2088	29	2	8	8	NUM
admet-2088	29	3	]	]	PUNCT
admet-2088	29	4	.	.	PUNCT
admet-2088	30	1	the	the	DET
admet-2088	30	2	most	most	ADV
admet-2088	30	3	prominent	prominent	ADJ
admet-2088	30	4	factors	factor	NOUN
admet-2088	30	5	for	for	ADP
admet-2088	30	6	melanoma	melanoma	NOUN
admet-2088	30	7	are	be	AUX
admet-2088	30	8	fair	fair	ADJ
admet-2088	30	9	skin	skin	NOUN
admet-2088	30	10	complexation	complexation	NOUN
admet-2088	30	11	,	,	PUNCT
admet-2088	30	12	family	family	NOUN
admet-2088	30	13	history	history	NOUN
admet-2088	30	14	of	of	ADP
admet-2088	30	15	the	the	DET
admet-2088	30	16	disease	disease	NOUN
admet-2088	30	17	,	,	PUNCT
admet-2088	30	18	appearance	appearance	NOUN
admet-2088	30	19	of	of	ADP
admet-2088	30	20	moles	mole	NOUN
admet-2088	30	21	in	in	ADP
admet-2088	30	22	the	the	DET
admet-2088	30	23	skin	skin	NOUN
admet-2088	30	24	,	,	PUNCT
admet-2088	30	25	immunosuppression	immunosuppression	NOUN
admet-2088	30	26	and	and	CCONJ
admet-2088	30	27	excessive	excessive	ADJ
admet-2088	30	28	exposure	exposure	NOUN
admet-2088	30	29	to	to	ADP
admet-2088	30	30	ultraviolet	ultraviolet	NOUN
admet-2088	30	31	(	(	PUNCT
admet-2088	30	32	uv	uv	NOUN
admet-2088	30	33	)	)	PUNCT
admet-2088	30	34	radiation	radiation	NOUN
admet-2088	31	1	[	[	X
admet-2088	31	2	7	7	NUM
admet-2088	31	3	]	]	PUNCT
admet-2088	31	4	.	.	PUNCT
admet-2088	32	1	the	the	DET
admet-2088	32	2	in	in	ADP
admet-2088	32	3	-	-	PUNCT
admet-2088	32	4	depth	depth	NOUN
admet-2088	32	5	study	study	NOUN
admet-2088	32	6	on	on	ADP
admet-2088	32	7	the	the	DET
admet-2088	32	8	immunology	immunology	NOUN
admet-2088	32	9	of	of	ADP
admet-2088	32	10	melanoma	melanoma	NOUN
admet-2088	32	11	suggested	suggest	VERB
admet-2088	32	12	that	that	SCONJ
admet-2088	32	13	the	the	DET
admet-2088	32	14	involvement	involvement	NOUN
admet-2088	32	15	of	of	ADP
admet-2088	32	16	mutation	mutation	NOUN
admet-2088	32	17	in	in	ADP
admet-2088	32	18	the	the	DET
admet-2088	32	19	genes	gene	NOUN
admet-2088	32	20	such	such	ADJ
admet-2088	32	21	as	as	ADP
admet-2088	32	22	v	v	NOUN
admet-2088	32	23	-	-	PUNCT
admet-2088	32	24	raf	raf	ADJ
admet-2088	32	25	murine	murine	ADJ
admet-2088	32	26	sarcoma	sarcoma	NOUN
admet-2088	32	27	viral	viral	ADJ
admet-2088	32	28	oncogene	oncogene	NOUN
admet-2088	32	29	homolog	homolog	NOUN
admet-2088	32	30	b1	b1	NOUN
admet-2088	32	31	(	(	PUNCT
admet-2088	32	32	braf	braf	PROPN
admet-2088	32	33	)	)	PUNCT
admet-2088	32	34	,	,	PUNCT
admet-2088	32	35	neuroblastoma	neuroblastoma	NOUN
admet-2088	32	36	ras	ras	X
admet-2088	32	37	viral	viral	ADJ
admet-2088	32	38	oncogene	oncogene	NOUN
admet-2088	32	39	homolog	homolog	NOUN
admet-2088	32	40	(	(	PUNCT
admet-2088	32	41	nras	nras	PROPN
admet-2088	32	42	)	)	PUNCT
admet-2088	32	43	and	and	CCONJ
admet-2088	32	44	nuclear	nuclear	ADJ
admet-2088	32	45	factor	factor	NOUN
admet-2088	32	46	i	i	PRON
admet-2088	32	47	(	(	PUNCT
admet-2088	32	48	nfi	nfi	PROPN
admet-2088	32	49	)	)	PUNCT
admet-2088	32	50	,	,	PUNCT
admet-2088	32	51	called	call	VERB
admet-2088	32	52	as	as	ADP
admet-2088	32	53	triple	triple	ADJ
admet-2088	32	54	-	-	PUNCT
admet-2088	32	55	wild	wild	ADJ
admet-2088	32	56	type	type	NOUN
admet-2088	32	57	genotype	genotype	NOUN
admet-2088	32	58	,	,	PUNCT
admet-2088	32	59	complicated	complicate	VERB
admet-2088	32	60	the	the	DET
admet-2088	32	61	treatment	treatment	NOUN
admet-2088	32	62	process	process	NOUN
admet-2088	32	63	[	[	X
admet-2088	32	64	9,10	9,10	NUM
admet-2088	32	65	]	]	X
admet-2088	32	66	.	.	PUNCT
admet-2088	33	1	melanoma	melanoma	PROPN
admet-2088	33	2	has	have	VERB
admet-2088	33	3	a	a	DET
admet-2088	33	4	5	5	NUM
admet-2088	33	5	-	-	PUNCT
admet-2088	33	6	year	year	NOUN
admet-2088	33	7	survival	survival	NOUN
admet-2088	33	8	rate	rate	NOUN
admet-2088	33	9	(	(	PUNCT
admet-2088	33	10	93	93	NUM
admet-2088	33	11	%	%	NOUN
admet-2088	33	12	)	)	PUNCT
admet-2088	33	13	and	and	CCONJ
admet-2088	33	14	is	be	AUX
admet-2088	33	15	even	even	ADV
admet-2088	33	16	curable	curable	ADJ
admet-2088	33	17	by	by	ADP
admet-2088	33	18	surgical	surgical	ADJ
admet-2088	33	19	resection	resection	NOUN
admet-2088	33	20	if	if	SCONJ
admet-2088	33	21	diagnosed	diagnose	VERB
admet-2088	33	22	at	at	ADP
admet-2088	33	23	early	early	ADJ
admet-2088	33	24	stages	stage	NOUN
admet-2088	33	25	.	.	PUNCT
admet-2088	34	1	if	if	SCONJ
admet-2088	34	2	not	not	PART
admet-2088	34	3	detected	detect	VERB
admet-2088	34	4	in	in	ADP
admet-2088	34	5	the	the	DET
admet-2088	34	6	early	early	ADJ
admet-2088	34	7	stages	stage	NOUN
admet-2088	34	8	(	(	PUNCT
admet-2088	34	9	stage	stage	NOUN
admet-2088	34	10	i	i	PRON
admet-2088	34	11	or	or	CCONJ
admet-2088	34	12	ii	ii	NUM
admet-2088	34	13	)	)	PUNCT
admet-2088	34	14	,	,	PUNCT
admet-2088	34	15	melanoma	melanoma	NOUN
admet-2088	34	16	metastasizes	metastasize	VERB
admet-2088	34	17	very	very	ADV
admet-2088	34	18	fast	fast	ADV
admet-2088	34	19	,	,	PUNCT
admet-2088	34	20	with	with	ADP
admet-2088	34	21	a	a	DET
admet-2088	34	22	survival	survival	NOUN
admet-2088	34	23	rate	rate	NOUN
admet-2088	34	24	of	of	ADP
admet-2088	34	25	only	only	ADV
admet-2088	34	26	six	six	NUM
admet-2088	34	27	months	month	NOUN
admet-2088	34	28	and	and	CCONJ
admet-2088	34	29	a	a	DET
admet-2088	34	30	decrease	decrease	NOUN
admet-2088	34	31	of	of	ADP
admet-2088	34	32	81	81	NUM
admet-2088	34	33	%	%	NOUN
admet-2088	34	34	in	in	ADP
admet-2088	34	35	the	the	DET
admet-2088	34	36	5	5	NUM
admet-2088	34	37	-	-	PUNCT
admet-2088	34	38	year	year	NOUN
admet-2088	34	39	survival	survival	NOUN
admet-2088	34	40	rate	rate	NOUN
admet-2088	34	41	[	[	X
admet-2088	34	42	11	11	NUM
admet-2088	34	43	]	]	PUNCT
admet-2088	34	44	.	.	PUNCT
admet-2088	35	1	however	however	ADV
admet-2088	35	2	,	,	PUNCT
admet-2088	35	3	the	the	DET
admet-2088	35	4	early	early	ADJ
admet-2088	35	5	-	-	PUNCT
admet-2088	35	6	stage	stage	NOUN
admet-2088	35	7	detection	detection	NOUN
admet-2088	35	8	of	of	ADP
admet-2088	35	9	tumours	tumours	PROPN
admet-2088	35	10	is	be	AUX
admet-2088	35	11	challenging	challenge	VERB
admet-2088	35	12	due	due	ADJ
admet-2088	35	13	to	to	ADP
admet-2088	35	14	the	the	DET
admet-2088	35	15	absence	absence	NOUN
admet-2088	35	16	of	of	ADP
admet-2088	35	17	clinical	clinical	ADJ
admet-2088	35	18	symptoms	symptom	NOUN
admet-2088	35	19	until	until	SCONJ
admet-2088	35	20	the	the	DET
admet-2088	35	21	disease	disease	NOUN
admet-2088	35	22	reaches	reach	VERB
admet-2088	35	23	the	the	DET
admet-2088	35	24	metastatic	metastatic	ADJ
admet-2088	35	25	stage	stage	NOUN
admet-2088	35	26	,	,	PUNCT
admet-2088	35	27	the	the	DET
admet-2088	35	28	lack	lack	NOUN
admet-2088	35	29	of	of	ADP
admet-2088	35	30	public	public	ADJ
admet-2088	35	31	awareness	awareness	NOUN
admet-2088	35	32	and	and	CCONJ
admet-2088	35	33	the	the	DET
admet-2088	35	34	unavailability	unavailability	NOUN
admet-2088	35	35	of	of	ADP
admet-2088	35	36	tumour	tumour	NOUN
admet-2088	35	37	-	-	PUNCT
admet-2088	35	38	detection	detection	NOUN
admet-2088	35	39	markers	marker	NOUN
admet-2088	36	1	[	[	X
admet-2088	36	2	12	12	NUM
admet-2088	36	3	]	]	PUNCT
admet-2088	36	4	.	.	PUNCT
admet-2088	37	1	currently	currently	ADV
admet-2088	37	2	,	,	PUNCT
admet-2088	37	3	five	five	NUM
admet-2088	37	4	types	type	NOUN
admet-2088	37	5	of	of	ADP
admet-2088	37	6	standard	standard	ADJ
admet-2088	37	7	treatment	treatment	NOUN
admet-2088	37	8	options	option	NOUN
admet-2088	37	9	are	be	AUX
admet-2088	37	10	available	available	ADJ
admet-2088	37	11	for	for	ADP
admet-2088	37	12	patients	patient	NOUN
admet-2088	37	13	suffering	suffer	VERB
admet-2088	37	14	from	from	ADP
admet-2088	37	15	melanoma	melanoma	NOUN
admet-2088	37	16	,	,	PUNCT
admet-2088	37	17	including	include	VERB
admet-2088	37	18	surgery	surgery	NOUN
admet-2088	37	19	,	,	PUNCT
admet-2088	37	20	chemotherapy	chemotherapy	NOUN
admet-2088	37	21	,	,	PUNCT
admet-2088	37	22	immunotherapy	immunotherapy	NOUN
admet-2088	37	23	,	,	PUNCT
admet-2088	37	24	targeted	target	VERB
admet-2088	37	25	therapy	therapy	NOUN
admet-2088	37	26	and	and	CCONJ
admet-2088	37	27	radiation	radiation	NOUN
admet-2088	37	28	therapy	therapy	NOUN
admet-2088	37	29	[	[	X
admet-2088	37	30	13	13	NUM
admet-2088	37	31	]	]	PUNCT
admet-2088	37	32	.	.	PUNCT
admet-2088	38	1	among	among	ADP
admet-2088	38	2	them	they	PRON
admet-2088	38	3	,	,	PUNCT
admet-2088	38	4	commonly	commonly	ADV
admet-2088	38	5	used	use	VERB
admet-2088	38	6	treatment	treatment	NOUN
admet-2088	38	7	options	option	NOUN
admet-2088	38	8	are	be	AUX
admet-2088	38	9	surgery	surgery	NOUN
admet-2088	38	10	(	(	PUNCT
admet-2088	38	11	limited	limit	VERB
admet-2088	38	12	to	to	ADP
admet-2088	38	13	early	early	ADJ
admet-2088	38	14	stage	stage	NOUN
admet-2088	38	15	)	)	PUNCT
admet-2088	38	16	,	,	PUNCT
admet-2088	38	17	chemotherapy	chemotherapy	NOUN
admet-2088	38	18	using	use	VERB
admet-2088	38	19	anticancer	anticancer	NOUN
admet-2088	38	20	therapeutic	therapeutic	ADJ
admet-2088	38	21	agents	agent	NOUN
admet-2088	38	22	such	such	ADJ
admet-2088	38	23	as	as	ADP
admet-2088	38	24	dacarbazine	dacarbazine	NOUN
admet-2088	38	25	and	and	CCONJ
admet-2088	38	26	radiotherapy	radiotherapy	NOUN
admet-2088	38	27	using	use	VERB
admet-2088	38	28	radiation	radiation	NOUN
admet-2088	38	29	are	be	AUX
admet-2088	38	30	limited	limit	VERB
admet-2088	38	31	by	by	ADP
admet-2088	38	32	serious	serious	ADJ
admet-2088	38	33	systemic	systemic	ADJ
admet-2088	38	34	effect	effect	NOUN
admet-2088	38	35	and	and	CCONJ
admet-2088	38	36	therapeutic	therapeutic	ADJ
admet-2088	38	37	ineffectiveness	ineffectiveness	NOUN
admet-2088	38	38	due	due	ADP
admet-2088	38	39	to	to	ADP
admet-2088	38	40	non	non	ADJ
admet-2088	38	41	-	-	ADJ
admet-2088	38	42	selectivity	selectivity	ADJ
admet-2088	38	43	,	,	PUNCT
admet-2088	38	44	large	large	ADJ
admet-2088	38	45	skin	skin	NOUN
admet-2088	38	46	defects	defect	NOUN
admet-2088	38	47	due	due	ADJ
admet-2088	38	48	to	to	ADP
admet-2088	38	49	radiation	radiation	NOUN
admet-2088	38	50	,	,	PUNCT
admet-2088	38	51	high	high	ADJ
admet-2088	38	52	risk	risk	NOUN
admet-2088	38	53	of	of	ADP
admet-2088	38	54	reoccurrence	reoccurrence	NOUN
admet-2088	38	55	and	and	CCONJ
admet-2088	38	56	therapeutic	therapeutic	ADJ
admet-2088	38	57	resistance	resistance	NOUN
admet-2088	38	58	[	[	X
admet-2088	38	59	14,15	14,15	NUM
admet-2088	38	60	]	]	PUNCT
admet-2088	38	61	.	.	PUNCT
admet-2088	39	1	then	then	ADV
admet-2088	39	2	comes	come	VERB
admet-2088	39	3	fda	fda	PROPN
admet-2088	39	4	-	-	PUNCT
admet-2088	39	5	approved	approve	VERB
admet-2088	39	6	systemic	systemic	ADJ
admet-2088	39	7	immunotherapy	immunotherapy	NOUN
admet-2088	39	8	employing	employ	VERB
admet-2088	39	9	cytotoxic	cytotoxic	ADJ
admet-2088	39	10	t	t	PROPN
admet-2088	39	11	-	-	PUNCT
admet-2088	39	12	lymphocyte	lymphocyte	NOUN
admet-2088	39	13	–	–	PUNCT
admet-2088	39	14	associated	associated	ADJ
admet-2088	39	15	antigen	antigen	ADP
admet-2088	39	16	4	4	NUM
admet-2088	39	17	(	(	PUNCT
admet-2088	39	18	ctla-4	ctla-4	X
admet-2088	39	19	)	)	PUNCT
admet-2088	39	20	and	and	CCONJ
admet-2088	39	21	programmed	program	VERB
admet-2088	39	22	death	death	NOUN
admet-2088	39	23	1	1	NUM
admet-2088	39	24	(	(	PUNCT
admet-2088	39	25	pd-1	pd-1	ADJ
admet-2088	39	26	)	)	PUNCT
admet-2088	39	27	immune	immune	ADJ
admet-2088	39	28	checkpoint	checkpoint	NOUN
admet-2088	39	29	inhibitors	inhibitor	NOUN
admet-2088	39	30	.	.	PUNCT
admet-2088	40	1	to	to	PART
admet-2088	40	2	avoid	avoid	VERB
admet-2088	40	3	systemic	systemic	ADJ
admet-2088	40	4	side	side	NOUN
admet-2088	40	5	effects	effect	NOUN
admet-2088	40	6	,	,	PUNCT
admet-2088	40	7	targeted	target	VERB
admet-2088	40	8	therapy	therapy	NOUN
admet-2088	40	9	was	be	AUX
admet-2088	40	10	introduced	introduce	VERB
admet-2088	40	11	where	where	SCONJ
admet-2088	40	12	braf	braf	NOUN
admet-2088	40	13	inhibitors	inhibitor	NOUN
admet-2088	40	14	(	(	PUNCT
admet-2088	40	15	e.g.	e.g.	ADV
admet-2088	40	16	,	,	PUNCT
admet-2088	40	17	vemurafenib	vemurafenib	PROPN
admet-2088	40	18	)	)	PUNCT
admet-2088	40	19	,	,	PUNCT
admet-2088	40	20	mek	mek	PROPN
admet-2088	40	21	inhibitors	inhibitor	NOUN
admet-2088	40	22	(	(	PUNCT
admet-2088	40	23	e.g.	e.g.	ADV
admet-2088	40	24	,	,	PUNCT
admet-2088	40	25	trametinib	trametinib	NOUN
admet-2088	40	26	)	)	PUNCT
admet-2088	40	27	and	and	CCONJ
admet-2088	40	28	c	c	X
admet-2088	40	29	-	-	PUNCT
admet-2088	40	30	kit	kit	NOUN
admet-2088	40	31	inhibitors	inhibitor	NOUN
admet-2088	40	32	specifically	specifically	ADV
admet-2088	40	33	target	target	VERB
admet-2088	40	34	the	the	DET
admet-2088	40	35	affected	affected	ADJ
admet-2088	40	36	mutated	mutate	VERB
admet-2088	40	37	melanoma	melanoma	NOUN
admet-2088	40	38	cells	cell	NOUN
admet-2088	40	39	[	[	X
admet-2088	40	40	16,17	16,17	NUM
admet-2088	40	41	]	]	PUNCT
admet-2088	40	42	.	.	PUNCT
admet-2088	41	1	these	these	DET
admet-2088	41	2	treatment	treatment	NOUN
admet-2088	41	3	options	option	NOUN
admet-2088	41	4	significantly	significantly	ADV
admet-2088	41	5	showed	show	VERB
admet-2088	41	6	progression	progression	NOUN
admet-2088	41	7	-	-	PUNCT
admet-2088	41	8	free	free	ADJ
admet-2088	41	9	survival	survival	NOUN
admet-2088	41	10	and	and	CCONJ
admet-2088	41	11	overall	overall	ADJ
admet-2088	41	12	longevity	longevity	NOUN
admet-2088	41	13	of	of	ADP
admet-2088	41	14	the	the	DET
admet-2088	41	15	patients	patient	NOUN
admet-2088	41	16	suffering	suffer	VERB
admet-2088	41	17	from	from	ADP
admet-2088	41	18	malignancy	malignancy	NOUN
admet-2088	41	19	.	.	PUNCT
admet-2088	42	1	however	however	ADV
admet-2088	42	2	,	,	PUNCT
admet-2088	42	3	they	they	PRON
admet-2088	42	4	suffer	suffer	VERB
admet-2088	42	5	due	due	ADP
admet-2088	42	6	to	to	ADP
admet-2088	42	7	a	a	DET
admet-2088	42	8	lack	lack	NOUN
admet-2088	42	9	of	of	ADP
admet-2088	42	10	efficacy	efficacy	NOUN
admet-2088	42	11	,	,	PUNCT
admet-2088	42	12	instances	instance	NOUN
admet-2088	42	13	of	of	ADP
admet-2088	42	14	adverse	adverse	ADJ
admet-2088	42	15	effects	effect	NOUN
admet-2088	42	16	and	and	CCONJ
admet-2088	42	17	,	,	PUNCT
admet-2088	42	18	more	more	ADV
admet-2088	42	19	importantly	importantly	ADV
admet-2088	42	20	,	,	PUNCT
admet-2088	42	21	resistance	resistance	NOUN
admet-2088	42	22	[	[	X
admet-2088	42	23	18	18	NUM
admet-2088	42	24	]	]	PUNCT
admet-2088	42	25	.	.	PUNCT
admet-2088	43	1	more	more	ADV
admet-2088	43	2	recently	recently	ADV
admet-2088	43	3	,	,	PUNCT
admet-2088	43	4	alternative	alternative	ADJ
admet-2088	43	5	therapy	therapy	NOUN
admet-2088	43	6	has	have	AUX
admet-2088	43	7	been	be	AUX
admet-2088	43	8	developed	develop	VERB
admet-2088	43	9	,	,	PUNCT
admet-2088	43	10	such	such	ADJ
admet-2088	43	11	as	as	ADP
admet-2088	43	12	photodynamic	photodynamic	ADJ
admet-2088	43	13	therapy	therapy	NOUN
admet-2088	43	14	(	(	PUNCT
admet-2088	43	15	pdt	pdt	NOUN
admet-2088	43	16	)	)	PUNCT
admet-2088	44	1	[	[	X
admet-2088	44	2	19	19	NUM
admet-2088	44	3	]	]	PUNCT
admet-2088	44	4	and	and	CCONJ
admet-2088	44	5	photothermal	photothermal	ADJ
admet-2088	44	6	therapy	therapy	NOUN
admet-2088	44	7	(	(	PUNCT
admet-2088	44	8	ptt	ptt	NOUN
admet-2088	44	9	)	)	PUNCT
admet-2088	45	1	[	[	X
admet-2088	45	2	20	20	NUM
admet-2088	45	3	]	]	PUNCT
admet-2088	45	4	.	.	PUNCT
admet-2088	46	1	however	however	ADV
admet-2088	46	2	,	,	PUNCT
admet-2088	46	3	the	the	DET
admet-2088	46	4	therapeutic	therapeutic	ADJ
admet-2088	46	5	efficacies	efficacy	NOUN
admet-2088	46	6	are	be	AUX
admet-2088	46	7	majorly	majorly	ADV
admet-2088	46	8	dependent	dependent	ADJ
admet-2088	46	9	on	on	ADP
admet-2088	46	10	the	the	DET
admet-2088	46	11	specific	specific	ADJ
admet-2088	46	12	accumulation	accumulation	NOUN
admet-2088	46	13	of	of	ADP
admet-2088	46	14	therapeutic	therapeutic	ADJ
admet-2088	46	15	agents	agent	NOUN
admet-2088	46	16	involved	involve	VERB
admet-2088	46	17	,	,	PUNCT
admet-2088	46	18	such	such	ADJ
admet-2088	46	19	as	as	ADP
admet-2088	46	20	photosensitizer	photosensitizer	NOUN
admet-2088	46	21	in	in	ADP
admet-2088	46	22	the	the	DET
admet-2088	46	23	case	case	NOUN
admet-2088	46	24	of	of	ADP
admet-2088	46	25	pdt	pdt	PROPN
admet-2088	46	26	and	and	CCONJ
admet-2088	46	27	photothermal	photothermal	ADJ
admet-2088	46	28	agents	agent	NOUN
admet-2088	46	29	in	in	ADP
admet-2088	46	30	the	the	DET
admet-2088	46	31	case	case	NOUN
admet-2088	46	32	of	of	ADP
admet-2088	46	33	ptt	ptt	NOUN
admet-2088	46	34	at	at	ADP
admet-2088	46	35	the	the	DET
admet-2088	46	36	melanoma	melanoma	NOUN
admet-2088	46	37	sites	site	NOUN
admet-2088	46	38	[	[	X
admet-2088	46	39	21	21	NUM
admet-2088	46	40	]	]	PUNCT
admet-2088	46	41	.	.	PUNCT
admet-2088	47	1	therefore	therefore	ADV
admet-2088	47	2	,	,	PUNCT
admet-2088	47	3	an	an	DET
admet-2088	47	4	urgent	urgent	ADJ
admet-2088	47	5	need	need	NOUN
admet-2088	47	6	is	be	AUX
admet-2088	47	7	to	to	PART
admet-2088	47	8	devise	devise	VERB
admet-2088	47	9	new	new	ADJ
admet-2088	47	10	effective	effective	ADJ
admet-2088	47	11	therapy	therapy	NOUN
admet-2088	47	12	to	to	PART
admet-2088	47	13	treat	treat	VERB
admet-2088	47	14	metastatic	metastatic	ADJ
admet-2088	47	15	melanoma	melanoma	NOUN
admet-2088	47	16	effectively	effectively	ADV
admet-2088	47	17	.	.	PUNCT
admet-2088	48	1	in	in	ADP
admet-2088	48	2	this	this	DET
admet-2088	48	3	context	context	NOUN
admet-2088	48	4	,	,	PUNCT
admet-2088	48	5	nanotechnology	nanotechnology	NOUN
admet-2088	48	6	involving	involve	VERB
admet-2088	48	7	nanoparticles	nanoparticle	NOUN
admet-2088	48	8	(	(	PUNCT
admet-2088	48	9	nps	nps	PROPN
admet-2088	48	10	)	)	PUNCT
admet-2088	48	11	of	of	ADP
admet-2088	48	12	dimension	dimension	NOUN
admet-2088	48	13	generally	generally	ADV
admet-2088	48	14	less	less	ADJ
admet-2088	48	15	than	than	ADP
admet-2088	48	16	100	100	NUM
admet-2088	48	17	nm	nm	NOUN
admet-2088	48	18	holds	hold	VERB
admet-2088	48	19	a	a	DET
admet-2088	48	20	crucial	crucial	ADJ
admet-2088	48	21	potential	potential	NOUN
admet-2088	48	22	as	as	ADP
admet-2088	48	23	an	an	DET
admet-2088	48	24	alternative	alternative	ADJ
admet-2088	48	25	therapy	therapy	NOUN
admet-2088	48	26	for	for	ADP
admet-2088	48	27	melanoma	melanoma	NOUN
admet-2088	48	28	due	due	ADP
admet-2088	48	29	to	to	ADP
admet-2088	48	30	their	their	PRON
admet-2088	48	31	target	target	NOUN
admet-2088	48	32	-	-	PUNCT
admet-2088	48	33	specific	specific	ADJ
admet-2088	48	34	delivery	delivery	NOUN
admet-2088	48	35	of	of	ADP
admet-2088	48	36	therapeutic	therapeutic	ADJ
admet-2088	48	37	agents	agent	NOUN
admet-2088	48	38	,	,	PUNCT
admet-2088	48	39	low	low	ADJ
admet-2088	48	40	side	side	NOUN
admet-2088	48	41	effects	effect	NOUN
admet-2088	48	42	,	,	PUNCT
admet-2088	48	43	increased	increase	VERB
admet-2088	48	44	circulation	circulation	NOUN
admet-2088	48	45	time	time	NOUN
admet-2088	48	46	,	,	PUNCT
admet-2088	48	47	higher	high	ADJ
admet-2088	48	48	bioavailability	bioavailability	NOUN
admet-2088	48	49	,	,	PUNCT
admet-2088	48	50	sustained	sustained	ADJ
admet-2088	48	51	drug	drug	NOUN
admet-2088	48	52	release	release	NOUN
admet-2088	48	53	and	and	CCONJ
admet-2088	48	54	ability	ability	NOUN
admet-2088	48	55	to	to	PART
admet-2088	48	56	carry	carry	VERB
admet-2088	48	57	and	and	CCONJ
admet-2088	48	58	delivery	delivery	NOUN
admet-2088	48	59	multiple	multiple	ADJ
admet-2088	48	60	therapeutic	therapeutic	ADJ
admet-2088	48	61	agents	agent	NOUN
admet-2088	48	62	for	for	ADP
admet-2088	48	63	synergistic	synergistic	ADJ
admet-2088	48	64	anticancer	anticancer	NOUN
admet-2088	48	65	effect	effect	NOUN
admet-2088	49	1	[	[	X
admet-2088	49	2	22,23	22,23	NOUN
admet-2088	49	3	]	]	PUNCT
admet-2088	49	4	.	.	PUNCT
admet-2088	50	1	in	in	ADP
admet-2088	50	2	addition	addition	NOUN
admet-2088	50	3	,	,	PUNCT
admet-2088	50	4	they	they	PRON
admet-2088	50	5	potentially	potentially	ADV
admet-2088	50	6	enhance	enhance	VERB
admet-2088	50	7	the	the	DET
admet-2088	50	8	solubility	solubility	NOUN
admet-2088	50	9	of	of	ADP
admet-2088	50	10	poorly	poorly	ADV
admet-2088	50	11	soluble	soluble	ADJ
admet-2088	50	12	drugs	drug	NOUN
admet-2088	50	13	,	,	PUNCT
admet-2088	50	14	protect	protect	VERB
admet-2088	50	15	the	the	DET
admet-2088	50	16	encapsulated	encapsulate	VERB
admet-2088	50	17	drugs	drug	NOUN
admet-2088	50	18	from	from	ADP
admet-2088	50	19	surrounding	surround	VERB
admet-2088	50	20	challenging	challenging	ADJ
admet-2088	50	21	environments	environment	NOUN
admet-2088	50	22	from	from	ADP
admet-2088	50	23	degradation	degradation	NOUN
admet-2088	50	24	,	,	PUNCT
admet-2088	50	25	and	and	CCONJ
admet-2088	50	26	improve	improve	VERB
admet-2088	50	27	intracellular	intracellular	NOUN
admet-2088	50	28	and	and	CCONJ
admet-2088	50	29	cross	cross	ADJ
admet-2088	50	30	-	-	ADJ
admet-2088	50	31	biological	biological	ADJ
admet-2088	50	32	membrane	membrane	NOUN
admet-2088	50	33	delivery	delivery	NOUN
admet-2088	51	1	[	[	X
admet-2088	51	2	24	24	NUM
admet-2088	51	3	]	]	PUNCT
admet-2088	51	4	.	.	PUNCT
admet-2088	52	1	based	base	VERB
admet-2088	52	2	on	on	ADP
admet-2088	52	3	drug	drug	NOUN
admet-2088	52	4	delivery	delivery	NOUN
admet-2088	52	5	applications	application	NOUN
admet-2088	52	6	,	,	PUNCT
admet-2088	52	7	nanomaterials	nanomaterial	NOUN
admet-2088	52	8	(	(	PUNCT
admet-2088	52	9	nms	nms	NOUN
admet-2088	52	10	)	)	PUNCT
admet-2088	52	11	are	be	AUX
admet-2088	52	12	mainly	mainly	ADV
admet-2088	52	13	classified	classify	VERB
admet-2088	52	14	into	into	ADP
admet-2088	52	15	two	two	NUM
admet-2088	52	16	categories	category	NOUN
admet-2088	52	17	:	:	PUNCT
admet-2088	52	18	(	(	PUNCT
admet-2088	52	19	i	i	NOUN
admet-2088	52	20	)	)	PUNCT
admet-2088	52	21	inorganic	inorganic	PROPN
admet-2088	52	22	nms	nms	NOUN
admet-2088	52	23	such	such	ADJ
admet-2088	52	24	as	as	ADP
admet-2088	52	25	silver	silver	NOUN
admet-2088	52	26	,	,	PUNCT
admet-2088	52	27	platinum	platinum	NOUN
admet-2088	52	28	,	,	PUNCT
admet-2088	52	29	gold	gold	NOUN
admet-2088	52	30	,	,	PUNCT
admet-2088	52	31	iron	iron	NOUN
admet-2088	52	32	,	,	PUNCT
admet-2088	52	33	copper	copper	NOUN
admet-2088	52	34	etc	etc	X
admet-2088	52	35	,	,	PUNCT
admet-2088	52	36	(	(	PUNCT
admet-2088	52	37	metallic	metallic	ADJ
admet-2088	52	38	nms	nms	NOUN
admet-2088	52	39	)	)	PUNCT
admet-2088	52	40	,	,	PUNCT
admet-2088	52	41	graphene	graphene	NOUN
admet-2088	52	42	admet	admet	PROPN
admet-2088	52	43	&	&	CCONJ
admet-2088	52	44	dmpk	dmpk	PROPN
admet-2088	52	45	12(1	12(1	PROPN
admet-2088	52	46	)	)	PUNCT
admet-2088	52	47	(	(	PUNCT
admet-2088	52	48	2024	2024	NUM
admet-2088	52	49	)	)	PUNCT
admet-2088	52	50	107	107	NUM
admet-2088	52	51	-	-	SYM
admet-2088	52	52	150	150	NUM
admet-2088	52	53	nanomaterial	nanomaterial	NOUN
admet-2088	52	54	-	-	PUNCT
admet-2088	52	55	based	base	VERB
admet-2088	52	56	drug	drug	NOUN
admet-2088	52	57	delivery	delivery	NOUN
admet-2088	52	58	systems	system	NOUN
admet-2088	52	59	for	for	ADP
admet-2088	52	60	melanoma	melanoma	NOUN
admet-2088	52	61	therapy	therapy	NOUN
admet-2088	52	62	doi	doi	NOUN
admet-2088	52	63	:	:	PUNCT
admet-2088	52	64	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	52	65	109	109	NUM
admet-2088	52	66	and	and	CCONJ
admet-2088	52	67	its	its	PRON
admet-2088	52	68	derivatives	derivative	NOUN
admet-2088	52	69	(	(	PUNCT
admet-2088	52	70	carbon	carbon	NOUN
admet-2088	52	71	-	-	PUNCT
admet-2088	52	72	based	base	VERB
admet-2088	52	73	nms	nms	NOUN
admet-2088	52	74	)	)	PUNCT
admet-2088	52	75	,	,	PUNCT
admet-2088	52	76	(	(	PUNCT
admet-2088	52	77	ii	ii	NOUN
admet-2088	52	78	)	)	PUNCT
admet-2088	52	79	organic	organic	ADJ
admet-2088	52	80	nms	nms	NOUN
admet-2088	52	81	including	include	VERB
admet-2088	52	82	the	the	DET
admet-2088	52	83	nps	nps	PROPN
admet-2088	52	84	derived	derive	VERB
admet-2088	52	85	from	from	ADP
admet-2088	52	86	polymer	polymer	NOUN
admet-2088	52	87	(	(	PUNCT
admet-2088	52	88	polymeric	polymeric	ADJ
admet-2088	52	89	nanocapsules	nanocapsule	NOUN
admet-2088	52	90	,	,	PUNCT
admet-2088	52	91	nanospheres	nanosphere	NOUN
admet-2088	52	92	,	,	PUNCT
admet-2088	52	93	dendrimers	dendrimer	NOUN
admet-2088	52	94	,	,	PUNCT
admet-2088	52	95	nanogel	nanogel	NOUN
admet-2088	52	96	,	,	PUNCT
admet-2088	52	97	etc	etc	X
admet-2088	52	98	)	)	PUNCT
admet-2088	52	99	and	and	CCONJ
admet-2088	52	100	lipids	lipid	NOUN
admet-2088	52	101	(	(	PUNCT
admet-2088	52	102	liposomes	liposome	NOUN
admet-2088	52	103	,	,	PUNCT
admet-2088	52	104	niosomes	niosome	NOUN
admet-2088	52	105	,	,	PUNCT
admet-2088	52	106	micelles	micelle	NOUN
admet-2088	52	107	,	,	PUNCT
admet-2088	52	108	solid	solid	ADJ
admet-2088	52	109	lipid	lipid	NOUN
admet-2088	52	110	nanoparticles	nanoparticle	NOUN
admet-2088	52	111	(	(	PUNCT
admet-2088	52	112	sln	sln	PROPN
admet-2088	52	113	)	)	PUNCT
admet-2088	52	114	,	,	PUNCT
admet-2088	52	115	etc	etc	X
admet-2088	52	116	.	.	X
admet-2088	52	117	)	)	PUNCT
admet-2088	53	1	[	[	X
admet-2088	53	2	25,26	25,26	X
admet-2088	53	3	]	]	X
admet-2088	53	4	.	.	PUNCT
admet-2088	54	1	these	these	DET
admet-2088	54	2	nps	nps	PROPN
admet-2088	54	3	can	can	AUX
admet-2088	54	4	carry	carry	VERB
admet-2088	54	5	and	and	CCONJ
admet-2088	54	6	deliver	deliver	VERB
admet-2088	54	7	therapeutic	therapeutic	ADJ
admet-2088	54	8	molecules	molecule	NOUN
admet-2088	54	9	such	such	ADJ
admet-2088	54	10	as	as	ADP
admet-2088	54	11	chemotherapeutic	chemotherapeutic	ADJ
admet-2088	54	12	agents	agent	NOUN
admet-2088	54	13	,	,	PUNCT
admet-2088	54	14	radiotherapeutics	radiotherapeutic	NOUN
admet-2088	54	15	,	,	PUNCT
admet-2088	54	16	photosensitizers	photosensitizer	NOUN
admet-2088	54	17	,	,	PUNCT
admet-2088	54	18	photothermal	photothermal	ADJ
admet-2088	54	19	agents	agent	NOUN
admet-2088	54	20	,	,	PUNCT
admet-2088	54	21	monoclonal	monoclonal	NOUN
admet-2088	54	22	antibodies	antibody	NOUN
admet-2088	54	23	(	(	PUNCT
admet-2088	54	24	mab	mab	NOUN
admet-2088	54	25	)	)	PUNCT
admet-2088	54	26	,	,	PUNCT
admet-2088	54	27	peptides	peptide	NOUN
admet-2088	54	28	and	and	CCONJ
admet-2088	54	29	proteins	protein	NOUN
admet-2088	54	30	to	to	ADP
admet-2088	54	31	the	the	DET
admet-2088	54	32	target	target	NOUN
admet-2088	54	33	site	site	NOUN
admet-2088	54	34	.	.	PUNCT
admet-2088	55	1	additionally	additionally	ADV
admet-2088	55	2	,	,	PUNCT
admet-2088	55	3	inorganic	inorganic	PROPN
admet-2088	55	4	nps	nps	PROPN
admet-2088	55	5	can	can	AUX
admet-2088	55	6	directly	directly	ADV
admet-2088	55	7	kill	kill	VERB
admet-2088	55	8	melanoma	melanoma	NOUN
admet-2088	55	9	cells	cell	NOUN
admet-2088	55	10	through	through	ADP
admet-2088	55	11	dna	dna	NOUN
admet-2088	55	12	damage	damage	NOUN
admet-2088	55	13	,	,	PUNCT
admet-2088	55	14	oxidative	oxidative	ADJ
admet-2088	55	15	stress	stress	NOUN
admet-2088	55	16	and	and	CCONJ
admet-2088	55	17	cell	cell	NOUN
admet-2088	55	18	membrane	membrane	NOUN
admet-2088	55	19	damage	damage	NOUN
admet-2088	55	20	[	[	X
admet-2088	55	21	27	27	NUM
admet-2088	55	22	]	]	PUNCT
admet-2088	55	23	.	.	PUNCT
admet-2088	56	1	skin	skin	NOUN
admet-2088	56	2	cancer	cancer	NOUN
admet-2088	56	3	and	and	CCONJ
admet-2088	56	4	melanoma	melanoma	NOUN
admet-2088	56	5	skin	skin	NOUN
admet-2088	56	6	is	be	AUX
admet-2088	56	7	the	the	DET
admet-2088	56	8	largest	large	ADJ
admet-2088	56	9	organ	organ	NOUN
admet-2088	56	10	of	of	ADP
admet-2088	56	11	the	the	DET
admet-2088	56	12	human	human	ADJ
admet-2088	56	13	body	body	NOUN
admet-2088	56	14	that	that	PRON
admet-2088	56	15	performs	perform	VERB
admet-2088	56	16	several	several	ADJ
admet-2088	56	17	functions	function	NOUN
admet-2088	56	18	,	,	PUNCT
admet-2088	56	19	including	include	VERB
admet-2088	56	20	the	the	DET
admet-2088	56	21	protection	protection	NOUN
admet-2088	56	22	of	of	ADP
admet-2088	56	23	internal	internal	ADJ
admet-2088	56	24	body	body	NOUN
admet-2088	56	25	parts	part	NOUN
admet-2088	56	26	from	from	ADP
admet-2088	56	27	pathogens	pathogen	NOUN
admet-2088	56	28	and	and	CCONJ
admet-2088	56	29	exogenous	exogenous	ADJ
admet-2088	56	30	particles	particle	NOUN
admet-2088	56	31	and	and	CCONJ
admet-2088	56	32	homeostasis	homeostasis	NOUN
admet-2088	56	33	of	of	ADP
admet-2088	56	34	the	the	DET
admet-2088	56	35	internal	internal	ADJ
admet-2088	56	36	medium	medium	NOUN
admet-2088	56	37	among	among	ADP
admet-2088	56	38	the	the	DET
admet-2088	56	39	important	important	ADJ
admet-2088	56	40	ones	one	NOUN
admet-2088	56	41	[	[	X
admet-2088	56	42	28,29	28,29	NUM
admet-2088	56	43	]	]	PUNCT
admet-2088	56	44	.	.	PUNCT
admet-2088	57	1	histologically	histologically	PROPN
admet-2088	57	2	,	,	PUNCT
admet-2088	57	3	the	the	DET
admet-2088	57	4	skin	skin	NOUN
admet-2088	57	5	comprises	comprise	VERB
admet-2088	57	6	three	three	NUM
admet-2088	57	7	distinct	distinct	ADJ
admet-2088	57	8	layers	layer	NOUN
admet-2088	57	9	:	:	PUNCT
admet-2088	57	10	the	the	DET
admet-2088	57	11	superficial	superficial	ADJ
admet-2088	57	12	epidermis	epidermis	NOUN
admet-2088	57	13	,	,	PUNCT
admet-2088	57	14	middle	middle	ADJ
admet-2088	57	15	dermis	dermis	NOUN
admet-2088	57	16	and	and	CCONJ
admet-2088	57	17	lower	low	ADJ
admet-2088	57	18	hypodermis	hypodermis	NOUN
admet-2088	57	19	or	or	CCONJ
admet-2088	57	20	subcutaneous	subcutaneous	ADJ
admet-2088	57	21	.	.	PUNCT
admet-2088	58	1	the	the	DET
admet-2088	58	2	skin	skin	NOUN
admet-2088	58	3	also	also	ADV
admet-2088	58	4	holds	hold	VERB
admet-2088	58	5	many	many	ADJ
admet-2088	58	6	types	type	NOUN
admet-2088	58	7	of	of	ADP
admet-2088	58	8	cells	cell	NOUN
admet-2088	58	9	,	,	PUNCT
admet-2088	58	10	such	such	ADJ
admet-2088	58	11	as	as	ADP
admet-2088	58	12	melanocytes	melanocyte	NOUN
admet-2088	58	13	,	,	PUNCT
admet-2088	58	14	keratinocytes	keratinocyte	NOUN
admet-2088	58	15	,	,	PUNCT
admet-2088	58	16	langerhans	langerhans	PROPN
admet-2088	58	17	,	,	PUNCT
admet-2088	58	18	and	and	CCONJ
admet-2088	58	19	dendritic	dendritic	ADJ
admet-2088	58	20	cells	cell	NOUN
admet-2088	58	21	in	in	ADP
admet-2088	58	22	the	the	DET
admet-2088	58	23	epidermis	epidermis	NOUN
admet-2088	58	24	.	.	PUNCT
admet-2088	59	1	figure	figure	NOUN
admet-2088	59	2	1	1	NUM
admet-2088	59	3	represents	represent	VERB
admet-2088	59	4	different	different	ADJ
admet-2088	59	5	skin	skin	NOUN
admet-2088	59	6	layers	layer	NOUN
admet-2088	59	7	along	along	ADP
admet-2088	59	8	with	with	ADP
admet-2088	59	9	prominent	prominent	ADJ
admet-2088	59	10	factors	factor	NOUN
admet-2088	59	11	of	of	ADP
admet-2088	59	12	melanoma	melanoma	NOUN
admet-2088	59	13	and	and	CCONJ
admet-2088	59	14	the	the	DET
admet-2088	59	15	skin	skin	NOUN
admet-2088	59	16	penetration	penetration	NOUN
admet-2088	59	17	pathways	pathway	NOUN
admet-2088	59	18	.	.	PUNCT
admet-2088	60	1	figure	figure	VERB
admet-2088	60	2	1	1	NUM
admet-2088	60	3	.	.	PUNCT
admet-2088	61	1	diagrammatic	diagrammatic	ADJ
admet-2088	61	2	representation	representation	NOUN
admet-2088	61	3	of	of	ADP
admet-2088	61	4	different	different	ADJ
admet-2088	61	5	skin	skin	NOUN
admet-2088	61	6	layers	layer	NOUN
admet-2088	61	7	,	,	PUNCT
admet-2088	61	8	prominent	prominent	ADJ
admet-2088	61	9	factors	factor	NOUN
admet-2088	61	10	of	of	ADP
admet-2088	61	11	melanoma	melanoma	NOUN
admet-2088	61	12	and	and	CCONJ
admet-2088	61	13	the	the	DET
admet-2088	61	14	skin	skin	NOUN
admet-2088	61	15	penetration	penetration	NOUN
admet-2088	61	16	pathways	pathway	NOUN
admet-2088	61	17	there	there	PRON
admet-2088	61	18	are	be	VERB
admet-2088	61	19	two	two	NUM
admet-2088	61	20	subtypes	subtype	NOUN
admet-2088	61	21	of	of	ADP
admet-2088	61	22	cancers	cancer	NOUN
admet-2088	61	23	such	such	ADJ
admet-2088	61	24	as	as	ADP
admet-2088	61	25	melanoma	melanoma	NOUN
admet-2088	61	26	and	and	CCONJ
admet-2088	61	27	non	non	ADJ
admet-2088	61	28	-	-	NOUN
admet-2088	61	29	melanoma	melanoma	ADJ
admet-2088	61	30	,	,	PUNCT
admet-2088	61	31	most	most	ADV
admet-2088	61	32	often	often	ADV
admet-2088	61	33	diagnosed	diagnose	VERB
admet-2088	61	34	in	in	ADP
admet-2088	61	35	the	the	DET
admet-2088	61	36	skin	skin	NOUN
admet-2088	61	37	of	of	ADP
admet-2088	61	38	the	the	DET
admet-2088	61	39	caucasian	caucasian	ADJ
admet-2088	61	40	population	population	NOUN
admet-2088	61	41	.	.	PUNCT
admet-2088	62	1	non	non	ADJ
admet-2088	62	2	-	-	ADJ
admet-2088	62	3	melanoma	melanoma	ADJ
admet-2088	62	4	subtypes	subtype	NOUN
admet-2088	62	5	of	of	ADP
admet-2088	62	6	skin	skin	NOUN
admet-2088	62	7	cancer	cancer	NOUN
admet-2088	62	8	are	be	AUX
admet-2088	62	9	most	most	ADV
admet-2088	62	10	prevalent	prevalent	ADJ
admet-2088	62	11	and	and	CCONJ
admet-2088	62	12	affect	affect	VERB
admet-2088	62	13	mainly	mainly	ADV
admet-2088	62	14	keratinocytes	keratinocyte	NOUN
admet-2088	62	15	or	or	CCONJ
admet-2088	62	16	epidermal	epidermal	ADJ
admet-2088	62	17	cells	cell	NOUN
admet-2088	62	18	.	.	PUNCT
admet-2088	63	1	it	it	PRON
admet-2088	63	2	includes	include	VERB
admet-2088	63	3	basal	basal	ADJ
admet-2088	63	4	cell	cell	NOUN
admet-2088	63	5	carcinoma	carcinoma	NOUN
admet-2088	63	6	,	,	PUNCT
admet-2088	63	7	sebaceous	sebaceous	ADJ
admet-2088	63	8	cell	cell	NOUN
admet-2088	63	9	carcinoma	carcinoma	NOUN
admet-2088	63	10	,	,	PUNCT
admet-2088	63	11	squamous	squamous	ADJ
admet-2088	63	12	cell	cell	NOUN
admet-2088	63	13	carcinoma	carcinoma	NOUN
admet-2088	63	14	,	,	PUNCT
admet-2088	63	15	bowen	bowen	PROPN
admet-2088	63	16	’s	’s	PART
admet-2088	63	17	disease	disease	NOUN
admet-2088	63	18	,	,	PUNCT
admet-2088	63	19	adnexal	adnexal	PROPN
admet-2088	63	20	tumours	tumours	PROPN
admet-2088	63	21	,	,	PUNCT
admet-2088	63	22	merkel	merkel	NOUN
admet-2088	63	23	cell	cell	NOUN
admet-2088	63	24	carcinoma	carcinoma	NOUN
admet-2088	63	25	and	and	CCONJ
admet-2088	63	26	kaposi	kaposi	PROPN
admet-2088	63	27	sarcoma	sarcoma	NOUN
admet-2088	64	1	[	[	X
admet-2088	64	2	30	30	NUM
admet-2088	64	3	]	]	PUNCT
admet-2088	64	4	.	.	PUNCT
admet-2088	65	1	however	however	ADV
admet-2088	65	2	,	,	PUNCT
admet-2088	65	3	melanoma	melanoma	NOUN
admet-2088	65	4	skin	skin	NOUN
admet-2088	65	5	cancer	cancer	NOUN
admet-2088	65	6	is	be	AUX
admet-2088	65	7	confined	confine	VERB
admet-2088	65	8	to	to	ADP
admet-2088	65	9	melanocytes	melanocyte	NOUN
admet-2088	65	10	and	and	CCONJ
admet-2088	65	11	is	be	AUX
admet-2088	65	12	considered	consider	VERB
admet-2088	65	13	as	as	ADP
admet-2088	65	14	most	most	ADV
admet-2088	65	15	aggressive	aggressive	ADJ
admet-2088	65	16	and	and	CCONJ
admet-2088	65	17	fatal	fatal	ADJ
admet-2088	65	18	[	[	X
admet-2088	65	19	31	31	NUM
admet-2088	65	20	]	]	PUNCT
admet-2088	65	21	.	.	PUNCT
admet-2088	66	1	melanoma	melanoma	PROPN
admet-2088	66	2	is	be	AUX
admet-2088	66	3	a	a	DET
admet-2088	66	4	malignant	malignant	ADJ
admet-2088	66	5	transformation	transformation	NOUN
admet-2088	66	6	of	of	ADP
admet-2088	66	7	pigment	pigment	NOUN
admet-2088	66	8	-	-	PUNCT
admet-2088	66	9	producing	produce	VERB
admet-2088	66	10	melanocytes	melanocyte	NOUN
admet-2088	66	11	mainly	mainly	ADV
admet-2088	66	12	present	present	ADJ
admet-2088	66	13	in	in	ADP
admet-2088	66	14	the	the	DET
admet-2088	66	15	stratum	stratum	NOUN
admet-2088	66	16	basale	basale	NOUN
admet-2088	66	17	of	of	ADP
admet-2088	66	18	the	the	DET
admet-2088	66	19	epidermal	epidermal	ADJ
admet-2088	66	20	layer	layer	NOUN
admet-2088	66	21	of	of	ADP
admet-2088	66	22	skin	skin	NOUN
admet-2088	66	23	,	,	PUNCT
admet-2088	66	24	inner	inner	ADJ
admet-2088	66	25	ear	ear	NOUN
admet-2088	66	26	,	,	PUNCT
admet-2088	66	27	uvea	uvea	NOUN
admet-2088	66	28	of	of	ADP
admet-2088	66	29	eyes	eye	NOUN
admet-2088	66	30	,	,	PUNCT
admet-2088	66	31	bones	bone	NOUN
admet-2088	66	32	and	and	CCONJ
admet-2088	66	33	hearts	heart	NOUN
admet-2088	66	34	.	.	PUNCT
admet-2088	67	1	various	various	ADJ
admet-2088	67	2	epidemiological	epidemiological	ADJ
admet-2088	67	3	studies	study	NOUN
admet-2088	67	4	have	have	AUX
admet-2088	67	5	proved	prove	VERB
admet-2088	67	6	that	that	SCONJ
admet-2088	67	7	the	the	DET
admet-2088	67	8	main	main	ADJ
admet-2088	67	9	predisposing	predispose	VERB
admet-2088	67	10	factors	factor	NOUN
admet-2088	67	11	for	for	ADP
admet-2088	67	12	melanoma	melanoma	NOUN
admet-2088	67	13	include	include	VERB
admet-2088	67	14	excessive	excessive	ADJ
admet-2088	67	15	uv	uv	NOUN
admet-2088	67	16	light	light	NOUN
admet-2088	67	17	exposure	exposure	NOUN
admet-2088	67	18	,	,	PUNCT
admet-2088	67	19	a	a	DET
admet-2088	67	20	family	family	NOUN
admet-2088	67	21	history	history	NOUN
admet-2088	67	22	of	of	ADP
admet-2088	67	23	melanoma	melanoma	NOUN
admet-2088	67	24	,	,	PUNCT
admet-2088	67	25	moles	mole	NOUN
admet-2088	67	26	and	and	CCONJ
admet-2088	67	27	a	a	DET
admet-2088	67	28	poor	poor	ADJ
admet-2088	67	29	immune	immune	ADJ
admet-2088	67	30	system	system	NOUN
admet-2088	67	31	[	[	X
admet-2088	67	32	32	32	NUM
admet-2088	67	33	]	]	PUNCT
admet-2088	67	34	.	.	PUNCT
admet-2088	68	1	there	there	PRON
admet-2088	68	2	is	be	VERB
admet-2088	68	3	a	a	DET
admet-2088	68	4	higher	high	ADJ
admet-2088	68	5	risk	risk	NOUN
admet-2088	68	6	of	of	ADP
admet-2088	68	7	melanoma	melanoma	NOUN
admet-2088	68	8	in	in	ADP
admet-2088	68	9	the	the	DET
admet-2088	68	10	population	population	NOUN
admet-2088	68	11	with	with	ADP
admet-2088	68	12	pale	pale	ADJ
admet-2088	68	13	skin	skin	NOUN
admet-2088	68	14	colour	colour	NOUN
admet-2088	68	15	,	,	PUNCT
admet-2088	68	16	i.e.	i.e.	X
admet-2088	68	17	,	,	PUNCT
admet-2088	68	18	caucasians	caucasian	NOUN
admet-2088	68	19	,	,	PUNCT
admet-2088	68	20	than	than	ADP
admet-2088	68	21	in	in	ADP
admet-2088	68	22	the	the	DET
admet-2088	68	23	population	population	NOUN
admet-2088	68	24	with	with	ADP
admet-2088	68	25	dark	dark	ADJ
admet-2088	68	26	skin	skin	NOUN
admet-2088	68	27	,	,	PUNCT
admet-2088	68	28	i.e.	i.e.	X
admet-2088	68	29	,	,	PUNCT
admet-2088	68	30	african	african	ADJ
admet-2088	68	31	and	and	CCONJ
admet-2088	68	32	east	east	NOUN
admet-2088	68	33	asians	asians	PROPN
admet-2088	68	34	[	[	X
admet-2088	68	35	33	33	NUM
admet-2088	68	36	]	]	PUNCT
admet-2088	68	37	.	.	PUNCT
admet-2088	69	1	the	the	DET
admet-2088	69	2	pigment	pigment	ADJ
admet-2088	69	3	melanin	melanin	NOUN
admet-2088	69	4	in	in	ADP
admet-2088	69	5	the	the	DET
admet-2088	69	6	skin	skin	NOUN
admet-2088	69	7	is	be	AUX
admet-2088	69	8	responsible	responsible	ADJ
admet-2088	69	9	for	for	ADP
admet-2088	69	10	“	"	PUNCT
admet-2088	69	11	suntan	suntan	PROPN
admet-2088	69	12	”	"	PUNCT
admet-2088	69	13	and	and	CCONJ
admet-2088	69	14	has	have	VERB
admet-2088	69	15	the	the	DET
admet-2088	69	16	function	function	NOUN
admet-2088	69	17	of	of	ADP
admet-2088	69	18	protecting	protect	VERB
admet-2088	69	19	the	the	DET
admet-2088	69	20	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	69	21	m.	m.	NOUN
admet-2088	69	22	kulkarni	kulkarni	PROPN
admet-2088	69	23	et	et	PROPN
admet-2088	69	24	al	al	PROPN
admet-2088	69	25	.	.	PROPN
admet-2088	69	26	admet	admet	PROPN
admet-2088	69	27	&	&	CCONJ
admet-2088	69	28	dmpk	dmpk	PROPN
admet-2088	69	29	12(1	12(1	PROPN
admet-2088	69	30	)	)	PUNCT
admet-2088	69	31	(	(	PUNCT
admet-2088	69	32	2024	2024	NUM
admet-2088	69	33	)	)	PUNCT
admet-2088	69	34	107	107	NUM
admet-2088	69	35	-	-	SYM
admet-2088	69	36	150	150	NUM
admet-2088	69	37	110	110	NUM
admet-2088	69	38	skin	skin	NOUN
admet-2088	69	39	against	against	ADP
admet-2088	69	40	harmful	harmful	ADJ
admet-2088	69	41	uv	uv	NOUN
admet-2088	69	42	radiation	radiation	NOUN
admet-2088	69	43	from	from	ADP
admet-2088	69	44	the	the	DET
admet-2088	69	45	sun	sun	NOUN
admet-2088	69	46	[	[	X
admet-2088	69	47	34	34	NUM
admet-2088	69	48	]	]	PUNCT
admet-2088	69	49	.	.	PUNCT
admet-2088	70	1	however	however	ADV
admet-2088	70	2	,	,	PUNCT
admet-2088	70	3	excessive	excessive	ADJ
admet-2088	70	4	sun	sun	NOUN
admet-2088	70	5	exposure	exposure	NOUN
admet-2088	70	6	may	may	AUX
admet-2088	70	7	have	have	VERB
admet-2088	70	8	a	a	DET
admet-2088	70	9	higher	high	ADJ
admet-2088	70	10	risk	risk	NOUN
admet-2088	70	11	for	for	ADP
admet-2088	70	12	melanoma	melanoma	NOUN
admet-2088	70	13	.	.	PUNCT
admet-2088	71	1	the	the	DET
admet-2088	71	2	origin	origin	NOUN
admet-2088	71	3	and	and	CCONJ
admet-2088	71	4	progress	progress	NOUN
admet-2088	71	5	of	of	ADP
admet-2088	71	6	melanoma	melanoma	NOUN
admet-2088	71	7	is	be	AUX
admet-2088	71	8	a	a	DET
admet-2088	71	9	multistep	multistep	ADJ
admet-2088	71	10	process	process	NOUN
admet-2088	71	11	with	with	ADP
admet-2088	71	12	five	five	NUM
admet-2088	71	13	distinct	distinct	ADJ
admet-2088	71	14	stages	stage	NOUN
admet-2088	71	15	(	(	PUNCT
admet-2088	71	16	stage	stage	NOUN
admet-2088	71	17	0	0	NUM
admet-2088	71	18	to	to	PART
admet-2088	71	19	stage	stage	VERB
admet-2088	71	20	4	4	NUM
admet-2088	71	21	)	)	PUNCT
admet-2088	71	22	bearing	bear	VERB
admet-2088	71	23	histological	histological	ADJ
admet-2088	71	24	and	and	CCONJ
admet-2088	71	25	clinical	clinical	ADJ
admet-2088	71	26	characteristics	characteristic	NOUN
admet-2088	71	27	[	[	X
admet-2088	71	28	12,35,36	12,35,36	NUM
admet-2088	71	29	]	]	PUNCT
admet-2088	71	30	.	.	PUNCT
admet-2088	72	1	stage	stage	NOUN
admet-2088	72	2	0	0	NUM
admet-2088	72	3	:	:	PUNCT
admet-2088	72	4	it	it	PRON
admet-2088	72	5	is	be	AUX
admet-2088	72	6	also	also	ADV
admet-2088	72	7	referred	refer	VERB
admet-2088	72	8	to	to	ADP
admet-2088	72	9	as	as	ADP
admet-2088	72	10	melanoma	melanoma	NOUN
admet-2088	72	11	in	in	ADP
admet-2088	72	12	situ	situ	NOUN
admet-2088	72	13	with	with	ADP
admet-2088	72	14	the	the	DET
admet-2088	72	15	presence	presence	NOUN
admet-2088	72	16	of	of	ADP
admet-2088	72	17	abnormal	abnormal	ADJ
admet-2088	72	18	melanocytes	melanocyte	NOUN
admet-2088	72	19	on	on	ADP
admet-2088	72	20	the	the	DET
admet-2088	72	21	upper	upper	ADJ
admet-2088	72	22	layer	layer	NOUN
admet-2088	72	23	of	of	ADP
admet-2088	72	24	the	the	DET
admet-2088	72	25	epidermis	epidermis	NOUN
admet-2088	72	26	.	.	PUNCT
admet-2088	73	1	nevi	nevi	PROPN
admet-2088	73	2	are	be	AUX
admet-2088	73	3	benign	benign	ADJ
admet-2088	73	4	skin	skin	NOUN
admet-2088	73	5	lesions	lesion	NOUN
admet-2088	73	6	,	,	PUNCT
admet-2088	73	7	but	but	CCONJ
admet-2088	73	8	most	most	ADV
admet-2088	73	9	often	often	ADV
admet-2088	73	10	,	,	PUNCT
admet-2088	73	11	they	they	PRON
admet-2088	73	12	transform	transform	VERB
admet-2088	73	13	into	into	ADP
admet-2088	73	14	malignant	malignant	ADJ
admet-2088	73	15	melanoma	melanoma	NOUN
admet-2088	73	16	.	.	PUNCT
admet-2088	74	1	increased	increase	VERB
admet-2088	74	2	melanoma	melanoma	NOUN
admet-2088	74	3	proliferation	proliferation	NOUN
admet-2088	74	4	may	may	AUX
admet-2088	74	5	lead	lead	VERB
admet-2088	74	6	to	to	ADP
admet-2088	74	7	these	these	DET
admet-2088	74	8	acquired	acquire	VERB
admet-2088	74	9	nevi	nevi	ADJ
admet-2088	74	10	(	(	PUNCT
admet-2088	74	11	mole	mole	NOUN
admet-2088	74	12	)	)	PUNCT
admet-2088	74	13	without	without	ADP
admet-2088	74	14	dysplasia	dysplasia	NOUN
admet-2088	74	15	.	.	PUNCT
admet-2088	75	1	stage	stage	NOUN
admet-2088	75	2	1	1	NUM
admet-2088	75	3	:	:	PUNCT
admet-2088	75	4	abnormal	abnormal	ADJ
admet-2088	75	5	nevi	nevi	NOUN
admet-2088	75	6	develops	develop	VERB
admet-2088	75	7	into	into	ADP
admet-2088	75	8	dysplastic	dysplastic	ADJ
admet-2088	75	9	nevi	nevi	NOUN
admet-2088	75	10	of	of	ADP
admet-2088	75	11	size	size	NOUN
admet-2088	75	12	ranges	range	VERB
admet-2088	75	13	between	between	ADP
admet-2088	75	14	1	1	NUM
admet-2088	75	15	to	to	PART
admet-2088	75	16	2	2	NUM
admet-2088	75	17	mm	mm	NOUN
admet-2088	75	18	,	,	PUNCT
admet-2088	75	19	showing	show	VERB
admet-2088	75	20	abnormal	abnormal	ADJ
admet-2088	75	21	differentiation	differentiation	NOUN
admet-2088	75	22	.	.	PUNCT
admet-2088	76	1	stage	stage	NOUN
admet-2088	76	2	2	2	NUM
admet-2088	76	3	:	:	PUNCT
admet-2088	76	4	the	the	DET
admet-2088	76	5	dysplastic	dysplastic	ADJ
admet-2088	76	6	nevi	nevi	NOUN
admet-2088	76	7	continue	continue	VERB
admet-2088	76	8	to	to	PART
admet-2088	76	9	differentiate	differentiate	VERB
admet-2088	76	10	and	and	CCONJ
admet-2088	76	11	enter	enter	VERB
admet-2088	76	12	into	into	ADP
admet-2088	76	13	the	the	DET
admet-2088	76	14	radial	radial	ADJ
admet-2088	76	15	growth	growth	NOUN
admet-2088	76	16	phase	phase	NOUN
admet-2088	76	17	(	(	PUNCT
admet-2088	76	18	rgp	rgp	PROPN
admet-2088	76	19	)	)	PUNCT
admet-2088	76	20	primary	primary	ADJ
admet-2088	76	21	tumour	tumour	NOUN
admet-2088	76	22	with	with	ADP
admet-2088	76	23	a	a	DET
admet-2088	76	24	size	size	NOUN
admet-2088	76	25	of	of	ADP
admet-2088	76	26	approximately	approximately	ADV
admet-2088	76	27	2	2	NUM
admet-2088	76	28	to	to	PART
admet-2088	76	29	4	4	NUM
admet-2088	76	30	mm	mm	NOUN
admet-2088	76	31	,	,	PUNCT
admet-2088	76	32	however	however	ADV
admet-2088	76	33	,	,	PUNCT
admet-2088	76	34	rgp	rgp	PROPN
admet-2088	76	35	is	be	AUX
admet-2088	76	36	only	only	ADV
admet-2088	76	37	confined	confine	VERB
admet-2088	76	38	to	to	ADP
admet-2088	76	39	the	the	DET
admet-2088	76	40	epidermis	epidermis	NOUN
admet-2088	76	41	without	without	ADP
admet-2088	76	42	the	the	DET
admet-2088	76	43	ability	ability	NOUN
admet-2088	76	44	to	to	PART
admet-2088	76	45	invade	invade	VERB
admet-2088	76	46	the	the	DET
admet-2088	76	47	dermis	dermis	NOUN
admet-2088	76	48	.	.	PUNCT
admet-2088	77	1	stage	stage	NOUN
admet-2088	77	2	3	3	NUM
admet-2088	77	3	:	:	PUNCT
admet-2088	77	4	through	through	ADP
admet-2088	77	5	genetic	genetic	ADJ
admet-2088	77	6	alteration	alteration	NOUN
admet-2088	77	7	,	,	PUNCT
admet-2088	77	8	rgp	rgp	PROPN
admet-2088	77	9	acquired	acquire	VERB
admet-2088	77	10	invasive	invasive	ADJ
admet-2088	77	11	potential	potential	NOUN
admet-2088	77	12	and	and	CCONJ
admet-2088	77	13	started	start	VERB
admet-2088	77	14	to	to	PART
admet-2088	77	15	infiltrate	infiltrate	VERB
admet-2088	77	16	the	the	DET
admet-2088	77	17	dermis	dermis	NOUN
admet-2088	77	18	and	and	CCONJ
admet-2088	77	19	spread	spread	VERB
admet-2088	77	20	to	to	ADP
admet-2088	77	21	a	a	DET
admet-2088	77	22	number	number	NOUN
admet-2088	77	23	of	of	ADP
admet-2088	77	24	lymph	lymph	NOUN
admet-2088	77	25	nodes	node	NOUN
admet-2088	77	26	.	.	PUNCT
admet-2088	78	1	this	this	PRON
admet-2088	78	2	is	be	AUX
admet-2088	78	3	called	call	VERB
admet-2088	78	4	the	the	DET
admet-2088	78	5	vertical	vertical	ADJ
admet-2088	78	6	growth	growth	NOUN
admet-2088	78	7	phase	phase	NOUN
admet-2088	78	8	(	(	PUNCT
admet-2088	78	9	vgp	vgp	NOUN
admet-2088	78	10	)	)	PUNCT
admet-2088	78	11	and	and	CCONJ
admet-2088	78	12	restricts	restrict	VERB
admet-2088	78	13	the	the	DET
admet-2088	78	14	treatment	treatment	NOUN
admet-2088	78	15	option	option	NOUN
admet-2088	78	16	due	due	ADP
admet-2088	78	17	to	to	ADP
admet-2088	78	18	their	their	PRON
admet-2088	78	19	self	self	NOUN
admet-2088	78	20	-	-	PUNCT
admet-2088	78	21	sufficient	sufficient	ADJ
admet-2088	78	22	growth	growth	NOUN
admet-2088	78	23	signals	signal	NOUN
admet-2088	78	24	and	and	CCONJ
admet-2088	78	25	invading	invade	VERB
admet-2088	78	26	ability	ability	NOUN
admet-2088	78	27	.	.	PUNCT
admet-2088	79	1	stage	stage	NOUN
admet-2088	79	2	4	4	NUM
admet-2088	79	3	:	:	PUNCT
admet-2088	79	4	metastatic	metastatic	ADJ
admet-2088	79	5	lesson	lesson	NOUN
admet-2088	79	6	is	be	AUX
admet-2088	79	7	developed	develop	VERB
admet-2088	79	8	and	and	CCONJ
admet-2088	79	9	spread	spread	VERB
admet-2088	79	10	to	to	ADP
admet-2088	79	11	distant	distant	ADJ
admet-2088	79	12	vital	vital	ADJ
admet-2088	79	13	organs	organ	NOUN
admet-2088	79	14	such	such	ADJ
admet-2088	79	15	as	as	ADP
admet-2088	79	16	the	the	DET
admet-2088	79	17	liver	liver	NOUN
admet-2088	79	18	,	,	PUNCT
admet-2088	79	19	brain	brain	NOUN
admet-2088	79	20	,	,	PUNCT
admet-2088	79	21	lung	lung	NOUN
admet-2088	79	22	and	and	CCONJ
admet-2088	79	23	gastrointestinal	gastrointestinal	ADJ
admet-2088	79	24	tract	tract	NOUN
admet-2088	79	25	(	(	PUNCT
admet-2088	79	26	git	git	NOUN
admet-2088	79	27	)	)	PUNCT
admet-2088	79	28	.	.	PUNCT
admet-2088	80	1	melanoma	melanoma	NOUN
admet-2088	80	2	is	be	AUX
admet-2088	80	3	basically	basically	ADV
admet-2088	80	4	classified	classify	VERB
admet-2088	80	5	into	into	ADP
admet-2088	80	6	four	four	NUM
admet-2088	80	7	types	type	NOUN
admet-2088	80	8	:	:	PUNCT
admet-2088	80	9	superficial	superficial	ADJ
admet-2088	80	10	spreading	spread	VERB
admet-2088	80	11	melanoma	melanoma	NOUN
admet-2088	80	12	,	,	PUNCT
admet-2088	80	13	nodular	nodular	ADJ
admet-2088	80	14	melanoma	melanoma	NOUN
admet-2088	80	15	,	,	PUNCT
admet-2088	80	16	lentiginous	lentiginous	ADJ
admet-2088	80	17	melanoma	melanoma	NOUN
admet-2088	80	18	and	and	CCONJ
admet-2088	80	19	acral	acral	ADJ
admet-2088	80	20	lentiginous	lentiginous	ADJ
admet-2088	80	21	melanoma	melanoma	NOUN
admet-2088	81	1	[	[	X
admet-2088	81	2	37	37	NUM
admet-2088	81	3	]	]	PUNCT
admet-2088	81	4	.	.	PUNCT
admet-2088	82	1	the	the	DET
admet-2088	82	2	superficial	superficial	ADJ
admet-2088	82	3	spreading	spread	VERB
admet-2088	82	4	melanoma	melanoma	NOUN
admet-2088	82	5	accounts	account	NOUN
admet-2088	82	6	for	for	ADP
admet-2088	82	7	70	70	NUM
admet-2088	82	8	%	%	NOUN
admet-2088	82	9	of	of	ADP
admet-2088	82	10	total	total	ADJ
admet-2088	82	11	melanoma	melanoma	NOUN
admet-2088	82	12	and	and	CCONJ
admet-2088	82	13	originates	originate	NOUN
admet-2088	82	14	from	from	ADP
admet-2088	82	15	pre	pre	ADJ
admet-2088	82	16	-	-	ADJ
admet-2088	82	17	existing	existing	ADJ
admet-2088	82	18	moles	mole	NOUN
admet-2088	82	19	.	.	PUNCT
admet-2088	83	1	it	it	PRON
admet-2088	83	2	is	be	AUX
admet-2088	83	3	frequently	frequently	ADV
admet-2088	83	4	seen	see	VERB
admet-2088	83	5	on	on	ADP
admet-2088	83	6	the	the	DET
admet-2088	83	7	backs	back	NOUN
admet-2088	83	8	of	of	ADP
admet-2088	83	9	males	male	NOUN
admet-2088	83	10	and	and	CCONJ
admet-2088	83	11	the	the	DET
admet-2088	83	12	legs	leg	NOUN
admet-2088	83	13	of	of	ADP
admet-2088	83	14	women	woman	NOUN
admet-2088	83	15	and	and	CCONJ
admet-2088	83	16	can	can	AUX
admet-2088	83	17	be	be	AUX
admet-2088	83	18	treated	treat	VERB
admet-2088	83	19	with	with	ADP
admet-2088	83	20	appropriate	appropriate	ADJ
admet-2088	83	21	excision	excision	NOUN
admet-2088	84	1	[	[	X
admet-2088	84	2	38	38	NUM
admet-2088	84	3	]	]	PUNCT
admet-2088	84	4	.	.	PUNCT
admet-2088	85	1	the	the	DET
admet-2088	85	2	nodular	nodular	ADJ
admet-2088	85	3	form	form	NOUN
admet-2088	85	4	of	of	ADP
admet-2088	85	5	melanoma	melanoma	NOUN
admet-2088	85	6	is	be	AUX
admet-2088	85	7	the	the	DET
admet-2088	85	8	most	most	ADV
admet-2088	85	9	aggressive	aggressive	ADJ
admet-2088	85	10	form	form	NOUN
admet-2088	85	11	and	and	CCONJ
admet-2088	85	12	grows	grow	VERB
admet-2088	85	13	faster	fast	ADV
admet-2088	85	14	without	without	ADP
admet-2088	85	15	rgp	rgp	PROPN
admet-2088	85	16	.	.	PUNCT
admet-2088	86	1	they	they	PRON
admet-2088	86	2	originate	originate	VERB
admet-2088	86	3	from	from	ADP
admet-2088	86	4	pre	pre	ADJ
admet-2088	86	5	-	-	ADJ
admet-2088	86	6	existing	existing	ADJ
admet-2088	86	7	bumps	bump	NOUN
admet-2088	86	8	with	with	ADP
admet-2088	86	9	blueblack	blueblack	NOUN
admet-2088	86	10	to	to	ADP
admet-2088	86	11	purplish	purplish	ADJ
admet-2088	86	12	colour	colour	NOUN
admet-2088	86	13	,	,	PUNCT
admet-2088	86	14	accounting	account	VERB
admet-2088	86	15	for	for	ADP
admet-2088	86	16	15	15	NUM
admet-2088	86	17	-	-	SYM
admet-2088	86	18	30	30	NUM
admet-2088	86	19	%	%	NOUN
admet-2088	86	20	of	of	ADP
admet-2088	86	21	total	total	ADJ
admet-2088	86	22	melanoma	melanoma	NOUN
admet-2088	86	23	manifested	manifest	VERB
admet-2088	86	24	.	.	PUNCT
admet-2088	87	1	lentiginous	lentiginous	ADJ
admet-2088	87	2	melanoma	melanoma	NOUN
admet-2088	87	3	is	be	AUX
admet-2088	87	4	generally	generally	ADV
admet-2088	87	5	observed	observe	VERB
admet-2088	87	6	as	as	ADP
admet-2088	87	7	a	a	DET
admet-2088	87	8	large	large	ADJ
admet-2088	87	9	and	and	CCONJ
admet-2088	87	10	flat	flat	ADJ
admet-2088	87	11	lesion	lesion	NOUN
admet-2088	87	12	on	on	ADP
admet-2088	87	13	the	the	DET
admet-2088	87	14	face	face	NOUN
admet-2088	87	15	of	of	ADP
admet-2088	87	16	light	light	NOUN
admet-2088	87	17	-	-	PUNCT
admet-2088	87	18	skinned	skinned	ADJ
admet-2088	87	19	older	old	ADJ
admet-2088	87	20	patients	patient	NOUN
admet-2088	87	21	with	with	ADP
admet-2088	87	22	sun	sun	NOUN
admet-2088	87	23	exposure	exposure	NOUN
admet-2088	87	24	for	for	ADP
admet-2088	87	25	a	a	DET
admet-2088	87	26	long	long	ADJ
admet-2088	87	27	time	time	NOUN
admet-2088	87	28	and	and	CCONJ
admet-2088	87	29	accounts	account	VERB
admet-2088	87	30	for	for	ADP
admet-2088	87	31	4	4	NUM
admet-2088	87	32	-	-	SYM
admet-2088	87	33	15	15	NUM
admet-2088	87	34	%	%	NOUN
admet-2088	87	35	of	of	ADP
admet-2088	87	36	total	total	ADJ
admet-2088	87	37	melanoma	melanoma	NOUN
admet-2088	87	38	incidence	incidence	NOUN
admet-2088	87	39	[	[	X
admet-2088	87	40	39	39	NUM
admet-2088	87	41	]	]	PUNCT
admet-2088	87	42	.	.	PUNCT
admet-2088	88	1	acral	acral	ADJ
admet-2088	88	2	lentiginous	lentiginous	ADJ
admet-2088	88	3	melanoma	melanoma	NOUN
admet-2088	88	4	lesions	lesion	NOUN
admet-2088	88	5	account	account	VERB
admet-2088	88	6	for	for	ADP
admet-2088	88	7	only	only	ADV
admet-2088	88	8	2	2	NUM
admet-2088	88	9	-	-	SYM
admet-2088	88	10	8	8	NUM
admet-2088	88	11	%	%	NOUN
admet-2088	88	12	of	of	ADP
admet-2088	88	13	melanomas	melanomas	NOUN
admet-2088	88	14	and	and	CCONJ
admet-2088	88	15	are	be	AUX
admet-2088	88	16	observed	observe	VERB
admet-2088	88	17	in	in	ADP
admet-2088	88	18	the	the	DET
admet-2088	88	19	palms	palm	NOUN
admet-2088	88	20	and	and	CCONJ
admet-2088	88	21	soles	sol	NOUN
admet-2088	89	1	[	[	X
admet-2088	89	2	38	38	NUM
admet-2088	89	3	]	]	PUNCT
admet-2088	89	4	.	.	PUNCT
admet-2088	90	1	genetic	genetic	ADJ
admet-2088	90	2	mutation	mutation	NOUN
admet-2088	90	3	and	and	CCONJ
admet-2088	90	4	pathways	pathway	NOUN
admet-2088	90	5	for	for	ADP
admet-2088	90	6	melanoma	melanoma	NOUN
admet-2088	90	7	the	the	DET
admet-2088	90	8	malignant	malignant	ADJ
admet-2088	90	9	transformation	transformation	NOUN
admet-2088	90	10	of	of	ADP
admet-2088	90	11	melanocytes	melanocyte	NOUN
admet-2088	90	12	mainly	mainly	ADV
admet-2088	90	13	involves	involve	VERB
admet-2088	90	14	genetic	genetic	ADJ
admet-2088	90	15	alteration	alteration	NOUN
admet-2088	90	16	resulting	result	VERB
admet-2088	90	17	in	in	ADP
admet-2088	90	18	oncogenic	oncogenic	ADJ
admet-2088	90	19	mutations	mutation	NOUN
admet-2088	90	20	such	such	ADJ
admet-2088	90	21	as	as	ADP
admet-2088	90	22	braf	braf	NOUN
admet-2088	90	23	(	(	PUNCT
admet-2088	90	24	b	b	X
admet-2088	90	25	-	-	PUNCT
admet-2088	90	26	raf	raf	NOUN
admet-2088	90	27	proto	proto	NOUN
admet-2088	90	28	-	-	PUNCT
admet-2088	90	29	oncogene	oncogene	ADJ
admet-2088	90	30	,	,	PUNCT
admet-2088	90	31	serine	serine	NOUN
admet-2088	90	32	/	/	SYM
admet-2088	90	33	threonine	threonine	ADJ
admet-2088	90	34	kinase	kinase	NOUN
admet-2088	90	35	)	)	PUNCT
admet-2088	90	36	mutation	mutation	NOUN
admet-2088	90	37	,	,	PUNCT
admet-2088	90	38	the	the	DET
admet-2088	90	39	appearance	appearance	NOUN
admet-2088	90	40	of	of	ADP
admet-2088	90	41	cyclin	cyclin	NOUN
admet-2088	90	42	-	-	PUNCT
admet-2088	90	43	dependent	dependent	ADJ
admet-2088	90	44	kinase	kinase	NOUN
admet-2088	90	45	inhibitor	inhibitor	PROPN
admet-2088	90	46	2a	2a	NUM
admet-2088	90	47	(	(	PUNCT
admet-2088	90	48	cdkn2a	cdkn2a	PROPN
admet-2088	90	49	)	)	PUNCT
admet-2088	90	50	locus	locus	NOUN
admet-2088	90	51	,	,	PUNCT
admet-2088	90	52	and	and	CCONJ
admet-2088	90	53	mutations	mutation	NOUN
admet-2088	90	54	in	in	ADP
admet-2088	90	55	melanin	melanin	NOUN
admet-2088	90	56	related	relate	VERB
admet-2088	90	57	genes	gene	NOUN
admet-2088	90	58	such	such	ADJ
admet-2088	90	59	as	as	ADP
admet-2088	90	60	melanocortin-1	melanocortin-1	NUM
admet-2088	90	61	receptor	receptor	NOUN
admet-2088	90	62	,	,	PUNCT
admet-2088	90	63	tyrosinase	tyrosinase	NOUN
admet-2088	90	64	,	,	PUNCT
admet-2088	90	65	etc	etc	X
admet-2088	90	66	.	.	X
admet-2088	91	1	[	[	X
admet-2088	91	2	40	40	NUM
admet-2088	91	3	]	]	PUNCT
admet-2088	91	4	.	.	PUNCT
admet-2088	92	1	the	the	DET
admet-2088	92	2	potential	potential	ADJ
admet-2088	92	3	cause	cause	NOUN
admet-2088	92	4	for	for	ADP
admet-2088	92	5	these	these	DET
admet-2088	92	6	mutations	mutation	NOUN
admet-2088	92	7	is	be	AUX
admet-2088	92	8	the	the	DET
admet-2088	92	9	enrichment	enrichment	NOUN
admet-2088	92	10	of	of	ADP
admet-2088	92	11	cytosine	cytosine	NOUN
admet-2088	92	12	to	to	ADP
admet-2088	92	13	thymine	thymine	NOUN
admet-2088	92	14	or	or	CCONJ
admet-2088	92	15	guanine	guanine	NOUN
admet-2088	92	16	to	to	PART
admet-2088	92	17	adenine	adenine	NOUN
admet-2088	92	18	induced	induce	VERB
admet-2088	92	19	by	by	ADP
admet-2088	92	20	uv	uv	NOUN
admet-2088	92	21	radiation	radiation	NOUN
admet-2088	92	22	[	[	X
admet-2088	92	23	41	41	NUM
admet-2088	92	24	]	]	PUNCT
admet-2088	92	25	.	.	PUNCT
admet-2088	93	1	the	the	DET
admet-2088	93	2	braf	braf	NOUN
admet-2088	93	3	oncogene	oncogene	NOUN
admet-2088	93	4	encodes	encode	NOUN
admet-2088	93	5	for	for	ADP
admet-2088	93	6	protein	protein	NOUN
admet-2088	93	7	kinase	kinase	NOUN
admet-2088	93	8	in	in	ADP
admet-2088	93	9	the	the	DET
admet-2088	93	10	mitogen	mitogen	NOUN
admet-2088	93	11	-	-	PUNCT
admet-2088	93	12	activated	activate	VERB
admet-2088	93	13	protein	protein	NOUN
admet-2088	93	14	kinase	kinase	NOUN
admet-2088	93	15	(	(	PUNCT
admet-2088	93	16	mapk	mapk	NOUN
admet-2088	93	17	)	)	PUNCT
admet-2088	93	18	pathway	pathway	NOUN
admet-2088	93	19	(	(	PUNCT
admet-2088	93	20	rtk	rtk	NOUN
admet-2088	93	21	-	-	PUNCT
admet-2088	93	22	ras	ras	NOUN
admet-2088	93	23	-	-	PUNCT
admet-2088	93	24	raf	raf	PROPN
admet-2088	93	25	-	-	PUNCT
admet-2088	93	26	mek	mek	PROPN
admet-2088	93	27	-	-	PUNCT
admet-2088	93	28	erk	erk	PROPN
admet-2088	93	29	)	)	PUNCT
admet-2088	94	1	[	[	X
admet-2088	94	2	42	42	NUM
admet-2088	94	3	]	]	PUNCT
admet-2088	94	4	.	.	PUNCT
admet-2088	95	1	mutation	mutation	NOUN
admet-2088	95	2	in	in	ADP
admet-2088	95	3	the	the	DET
admet-2088	95	4	braf	braf	NOUN
admet-2088	95	5	and	and	CCONJ
admet-2088	95	6	nras	nras	PROPN
admet-2088	95	7	accounts	account	VERB
admet-2088	95	8	for	for	ADP
admet-2088	95	9	50	50	NUM
admet-2088	95	10	and	and	CCONJ
admet-2088	95	11	30	30	NUM
admet-2088	95	12	%	%	NOUN
admet-2088	95	13	of	of	ADP
admet-2088	95	14	the	the	DET
admet-2088	95	15	total	total	ADJ
admet-2088	95	16	cause	cause	NOUN
admet-2088	95	17	of	of	ADP
admet-2088	95	18	melanoma	melanoma	NOUN
admet-2088	95	19	,	,	PUNCT
admet-2088	95	20	respectively	respectively	ADV
admet-2088	95	21	.	.	PUNCT
admet-2088	96	1	another	another	DET
admet-2088	96	2	important	important	ADJ
admet-2088	96	3	signalling	signal	VERB
admet-2088	96	4	pathway	pathway	NOUN
admet-2088	96	5	involved	involve	VERB
admet-2088	96	6	in	in	ADP
admet-2088	96	7	cell	cell	NOUN
admet-2088	96	8	growth	growth	NOUN
admet-2088	96	9	and	and	CCONJ
admet-2088	96	10	apoptosis	apoptosis	NOUN
admet-2088	96	11	in	in	ADP
admet-2088	96	12	melanoma	melanoma	NOUN
admet-2088	96	13	is	be	AUX
admet-2088	96	14	the	the	DET
admet-2088	96	15	activation	activation	NOUN
admet-2088	96	16	of	of	ADP
admet-2088	96	17	the	the	DET
admet-2088	96	18	phosphatidylinositol	phosphatidylinositol	NOUN
admet-2088	96	19	3	3	NUM
admet-2088	96	20	-	-	PUNCT
admet-2088	96	21	kinase	kinase	NOUN
admet-2088	96	22	(	(	PUNCT
admet-2088	96	23	p13k	p13k	NOUN
admet-2088	96	24	/	/	SYM
admet-2088	96	25	akt	akt	PROPN
admet-2088	96	26	)	)	PUNCT
admet-2088	96	27	pathway	pathway	NOUN
admet-2088	96	28	.	.	PUNCT
admet-2088	97	1	tyrosine	tyrosine	PROPN
admet-2088	97	2	kinase	kinase	PROPN
admet-2088	97	3	receptors	receptor	NOUN
admet-2088	97	4	directly	directly	ADV
admet-2088	97	5	activate	activate	VERB
admet-2088	97	6	the	the	DET
admet-2088	97	7	pi3	pi3	NOUN
admet-2088	97	8	kinases	kinase	NOUN
admet-2088	97	9	,	,	PUNCT
admet-2088	97	10	resulting	result	VERB
admet-2088	97	11	in	in	ADP
admet-2088	97	12	the	the	DET
admet-2088	97	13	phosphorylation	phosphorylation	NOUN
admet-2088	97	14	of	of	ADP
admet-2088	97	15	pip2	pip2	NOUN
admet-2088	97	16	to	to	ADP
admet-2088	97	17	pip3	pip3	PROPN
admet-2088	97	18	.	.	PUNCT
admet-2088	98	1	these	these	DET
admet-2088	98	2	events	event	NOUN
admet-2088	98	3	led	lead	VERB
admet-2088	98	4	to	to	ADP
admet-2088	98	5	akt	akt	PROPN
admet-2088	98	6	’s	’s	PART
admet-2088	98	7	phosphorylation	phosphorylation	NOUN
admet-2088	98	8	,	,	PUNCT
admet-2088	98	9	which	which	PRON
admet-2088	98	10	induces	induce	VERB
admet-2088	98	11	effector	effector	NOUN
admet-2088	98	12	molecules	molecule	NOUN
admet-2088	98	13	for	for	ADP
admet-2088	98	14	regulating	regulate	VERB
admet-2088	98	15	cell	cell	NOUN
admet-2088	98	16	proliferation	proliferation	NOUN
admet-2088	98	17	.	.	PUNCT
admet-2088	99	1	activated	activate	VERB
admet-2088	99	2	akt	akt	PROPN
admet-2088	99	3	inhibits	inhibit	VERB
admet-2088	99	4	gsk3β	gsk3β	PROPN
admet-2088	99	5	and	and	CCONJ
admet-2088	99	6	induces	induce	VERB
admet-2088	99	7	the	the	DET
admet-2088	99	8	accumulation	accumulation	NOUN
admet-2088	99	9	of	of	ADP
admet-2088	99	10	β	β	NOUN
admet-2088	99	11	-	-	NOUN
admet-2088	99	12	catenin	catenin	NOUN
admet-2088	99	13	and	and	CCONJ
admet-2088	99	14	their	their	PRON
admet-2088	99	15	movement	movement	NOUN
admet-2088	99	16	into	into	ADP
admet-2088	99	17	the	the	DET
admet-2088	99	18	nucleus	nucleus	NOUN
admet-2088	99	19	.	.	PUNCT
admet-2088	100	1	further	far	ADV
admet-2088	100	2	,	,	PUNCT
admet-2088	100	3	β	β	X
admet-2088	100	4	-	-	ADJ
admet-2088	100	5	catenin	catenin	ADJ
admet-2088	100	6	coactivates	coactivate	VERB
admet-2088	100	7	transcription	transcription	NOUN
admet-2088	100	8	factor	factor	NOUN
admet-2088	100	9	(	(	PUNCT
admet-2088	100	10	t	t	NOUN
admet-2088	100	11	-	-	PUNCT
admet-2088	100	12	cell	cell	NOUN
admet-2088	100	13	factor	factor	NOUN
admet-2088	100	14	)	)	PUNCT
admet-2088	100	15	,	,	PUNCT
admet-2088	100	16	leading	lead	VERB
admet-2088	100	17	to	to	ADP
admet-2088	100	18	the	the	DET
admet-2088	100	19	upregulation	upregulation	NOUN
admet-2088	100	20	of	of	ADP
admet-2088	100	21	c	c	NOUN
admet-2088	100	22	-	-	PUNCT
admet-2088	100	23	myc	myc	NOUN
admet-2088	100	24	and	and	CCONJ
admet-2088	100	25	cyclin	cyclin	PROPN
admet-2088	100	26	d	d	PROPN
admet-2088	100	27	and	and	CCONJ
admet-2088	100	28	inducing	induce	VERB
admet-2088	100	29	cell	cell	NOUN
admet-2088	100	30	proliferation	proliferation	NOUN
admet-2088	100	31	.	.	PUNCT
admet-2088	101	1	in	in	ADP
admet-2088	101	2	addition	addition	NOUN
admet-2088	101	3	,	,	PUNCT
admet-2088	101	4	mutations	mutation	NOUN
admet-2088	101	5	in	in	ADP
admet-2088	101	6	tyrosine	tyrosine	PROPN
admet-2088	101	7	kinase	kinase	PROPN
admet-2088	101	8	receptor	receptor	NOUN
admet-2088	101	9	(	(	PUNCT
admet-2088	101	10	c	c	NOUN
admet-2088	101	11	-	-	PUNCT
admet-2088	101	12	kit	kit	NOUN
admet-2088	101	13	)	)	PUNCT
admet-2088	101	14	activate	activate	VERB
admet-2088	101	15	the	the	DET
admet-2088	101	16	pi3k	pi3k	PROPN
admet-2088	101	17	/	/	SYM
admet-2088	101	18	akt	akt	PROPN
admet-2088	101	19	pathways	pathway	NOUN
admet-2088	101	20	and	and	CCONJ
admet-2088	101	21	induce	induce	VERB
admet-2088	101	22	tumour	tumour	ADJ
admet-2088	101	23	progression	progression	NOUN
admet-2088	101	24	[	[	X
admet-2088	101	25	43	43	NUM
admet-2088	101	26	]	]	PUNCT
admet-2088	101	27	.	.	PUNCT
admet-2088	102	1	admet	admet	PROPN
admet-2088	102	2	&	&	CCONJ
admet-2088	102	3	dmpk	dmpk	PROPN
admet-2088	102	4	12(1	12(1	PROPN
admet-2088	102	5	)	)	PUNCT
admet-2088	102	6	(	(	PUNCT
admet-2088	102	7	2024	2024	NUM
admet-2088	102	8	)	)	PUNCT
admet-2088	102	9	107	107	NUM
admet-2088	102	10	-	-	SYM
admet-2088	102	11	150	150	NUM
admet-2088	102	12	nanomaterial	nanomaterial	NOUN
admet-2088	102	13	-	-	PUNCT
admet-2088	102	14	based	base	VERB
admet-2088	102	15	drug	drug	NOUN
admet-2088	102	16	delivery	delivery	NOUN
admet-2088	102	17	systems	system	NOUN
admet-2088	102	18	for	for	ADP
admet-2088	102	19	melanoma	melanoma	NOUN
admet-2088	102	20	therapy	therapy	NOUN
admet-2088	102	21	doi	doi	NOUN
admet-2088	102	22	:	:	PUNCT
admet-2088	102	23	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	102	24	111	111	NUM
admet-2088	102	25	the	the	DET
admet-2088	102	26	significant	significant	ADJ
admet-2088	102	27	advancement	advancement	NOUN
admet-2088	102	28	in	in	ADP
admet-2088	102	29	immunology	immunology	NOUN
admet-2088	102	30	indicated	indicate	VERB
admet-2088	102	31	that	that	SCONJ
admet-2088	102	32	melanin	melanin	NOUN
admet-2088	102	33	tumorigenesis	tumorigenesis	NOUN
admet-2088	102	34	is	be	AUX
admet-2088	102	35	not	not	PART
admet-2088	102	36	only	only	ADV
admet-2088	102	37	caused	cause	VERB
admet-2088	102	38	due	due	ADJ
admet-2088	102	39	to	to	ADP
admet-2088	102	40	genetic	genetic	ADJ
admet-2088	102	41	mutation	mutation	NOUN
admet-2088	102	42	but	but	CCONJ
admet-2088	102	43	also	also	ADV
admet-2088	102	44	induced	induce	VERB
admet-2088	102	45	by	by	ADP
admet-2088	102	46	immunology	immunology	NOUN
admet-2088	102	47	.	.	PUNCT
admet-2088	103	1	this	this	PRON
admet-2088	103	2	is	be	AUX
admet-2088	103	3	justified	justify	VERB
admet-2088	103	4	because	because	SCONJ
admet-2088	103	5	:	:	PUNCT
admet-2088	103	6	(	(	PUNCT
admet-2088	103	7	i	i	NOUN
admet-2088	103	8	)	)	PUNCT
admet-2088	103	9	melanoma	melanoma	PROPN
admet-2088	103	10	can	can	AUX
admet-2088	103	11	disrupt	disrupt	VERB
admet-2088	103	12	antigen	antigen	ADJ
admet-2088	103	13	presentation	presentation	NOUN
admet-2088	103	14	mechanism	mechanism	NOUN
admet-2088	103	15	by	by	ADP
admet-2088	103	16	avoiding	avoid	VERB
admet-2088	103	17	immune	immune	ADJ
admet-2088	103	18	recognition	recognition	NOUN
admet-2088	103	19	and	and	CCONJ
admet-2088	103	20	elimination	elimination	NOUN
admet-2088	103	21	.	.	PUNCT
admet-2088	104	1	for	for	ADP
admet-2088	104	2	example	example	NOUN
admet-2088	104	3	,	,	PUNCT
admet-2088	104	4	downregulation	downregulation	NOUN
admet-2088	104	5	of	of	ADP
admet-2088	104	6	major	major	ADJ
admet-2088	104	7	histocompatibility	histocompatibility	NOUN
admet-2088	104	8	complex	complex	ADJ
admet-2088	104	9	class	class	NOUN
admet-2088	104	10	-	-	PUNCT
admet-2088	104	11	i	i	PRON
admet-2088	104	12	molecules	molecule	NOUN
admet-2088	104	13	,	,	PUNCT
admet-2088	104	14	thereby	thereby	ADV
admet-2088	104	15	putting	put	VERB
admet-2088	104	16	an	an	DET
admet-2088	104	17	end	end	NOUN
admet-2088	104	18	to	to	ADP
admet-2088	104	19	antigen	antigen	ADJ
admet-2088	104	20	processing	processing	NOUN
admet-2088	104	21	reaction	reaction	NOUN
admet-2088	104	22	.	.	PUNCT
admet-2088	105	1	(	(	PUNCT
admet-2088	105	2	ii	ii	NOUN
admet-2088	105	3	)	)	PUNCT
admet-2088	105	4	upregulation	upregulation	NOUN
admet-2088	105	5	involving	involve	VERB
admet-2088	105	6	programmed	program	VERB
admet-2088	105	7	death	death	NOUN
admet-2088	105	8	ligand-1	ligand-1	NUM
admet-2088	105	9	(	(	PUNCT
admet-2088	105	10	pd	pd	NOUN
admet-2088	105	11	-	-	PUNCT
admet-2088	105	12	l1	l1	NOUN
admet-2088	105	13	)	)	PUNCT
admet-2088	105	14	expression	expression	NOUN
admet-2088	105	15	on	on	ADP
admet-2088	105	16	the	the	DET
admet-2088	105	17	melanoma	melanoma	NOUN
admet-2088	105	18	surface	surface	NOUN
admet-2088	105	19	resulting	result	VERB
admet-2088	105	20	in	in	ADP
admet-2088	105	21	the	the	DET
admet-2088	105	22	suppression	suppression	NOUN
admet-2088	105	23	of	of	ADP
admet-2088	105	24	the	the	DET
admet-2088	105	25	effector	effector	NOUN
admet-2088	105	26	function	function	NOUN
admet-2088	105	27	of	of	ADP
admet-2088	105	28	tumour	tumour	NOUN
admet-2088	105	29	infiltration	infiltration	NOUN
admet-2088	105	30	lymphocytes	lymphocyte	VERB
admet-2088	105	31	via	via	ADP
admet-2088	105	32	interaction	interaction	NOUN
admet-2088	105	33	between	between	ADP
admet-2088	105	34	pd-1	pd-1	ADJ
admet-2088	105	35	and	and	CCONJ
admet-2088	105	36	pd	pd	PROPN
admet-2088	105	37	-	-	PROPN
admet-2088	105	38	l1	l1	PROPN
admet-2088	105	39	[	[	X
admet-2088	105	40	44	44	NUM
admet-2088	105	41	]	]	PUNCT
admet-2088	105	42	,	,	PUNCT
admet-2088	105	43	(	(	PUNCT
admet-2088	105	44	iii	iii	X
admet-2088	105	45	)	)	PUNCT
admet-2088	105	46	the	the	DET
admet-2088	105	47	creation	creation	NOUN
admet-2088	105	48	of	of	ADP
admet-2088	105	49	suppressive	suppressive	ADJ
admet-2088	105	50	tumour	tumour	NOUN
admet-2088	105	51	microenvironment	microenvironment	NOUN
admet-2088	105	52	due	due	ADP
admet-2088	105	53	to	to	ADP
admet-2088	105	54	the	the	DET
admet-2088	105	55	role	role	NOUN
admet-2088	105	56	of	of	ADP
admet-2088	105	57	immunosuppressive	immunosuppressive	ADJ
admet-2088	105	58	cells	cell	NOUN
admet-2088	105	59	in	in	ADP
admet-2088	105	60	melanin	melanin	NOUN
admet-2088	105	61	transformation	transformation	NOUN
admet-2088	105	62	,	,	PUNCT
admet-2088	105	63	including	include	VERB
admet-2088	105	64	regulatory	regulatory	ADJ
admet-2088	105	65	t	t	NOUN
admet-2088	105	66	cells	cell	NOUN
admet-2088	105	67	(	(	PUNCT
admet-2088	105	68	tregs	treg	NOUN
admet-2088	105	69	)	)	PUNCT
admet-2088	105	70	,	,	PUNCT
admet-2088	105	71	myeloid	myeloid	NOUN
admet-2088	105	72	-	-	PUNCT
admet-2088	105	73	derived	derive	VERB
admet-2088	105	74	suppressor	suppressor	NOUN
admet-2088	105	75	cells	cell	NOUN
admet-2088	105	76	(	(	PUNCT
admet-2088	105	77	mdscs	mdsc	NOUN
admet-2088	105	78	)	)	PUNCT
admet-2088	105	79	and	and	CCONJ
admet-2088	105	80	the	the	DET
admet-2088	105	81	enzymes	enzyme	NOUN
admet-2088	105	82	and	and	CCONJ
admet-2088	105	83	molecules	molecule	NOUN
admet-2088	105	84	released	release	VERB
admet-2088	105	85	by	by	ADP
admet-2088	105	86	these	these	DET
admet-2088	105	87	cells	cell	NOUN
admet-2088	105	88	such	such	ADJ
admet-2088	105	89	as	as	ADP
admet-2088	105	90	reactive	reactive	ADJ
admet-2088	105	91	oxygen	oxygen	NOUN
admet-2088	105	92	species	specie	NOUN
admet-2088	105	93	(	(	PUNCT
admet-2088	105	94	ros	ros	PROPN
admet-2088	105	95	)	)	PUNCT
admet-2088	105	96	,	,	PUNCT
admet-2088	105	97	arginase1	arginase1	NOUN
admet-2088	105	98	,	,	PUNCT
admet-2088	105	99	etc	etc	X
admet-2088	105	100	.	.	X
admet-2088	106	1	[	[	X
admet-2088	106	2	45	45	NUM
admet-2088	106	3	]	]	PUNCT
admet-2088	106	4	.	.	PUNCT
admet-2088	107	1	conventional	conventional	ADJ
admet-2088	107	2	treatment	treatment	NOUN
admet-2088	107	3	options	option	NOUN
admet-2088	107	4	and	and	CCONJ
admet-2088	107	5	their	their	PRON
admet-2088	107	6	limitations	limitation	NOUN
admet-2088	107	7	melanoma	melanoma	NOUN
admet-2088	107	8	has	have	VERB
admet-2088	107	9	a	a	DET
admet-2088	107	10	very	very	ADV
admet-2088	107	11	high	high	ADJ
admet-2088	107	12	metastatic	metastatic	ADJ
admet-2088	107	13	potential	potential	NOUN
admet-2088	107	14	accompanied	accompany	VERB
admet-2088	107	15	by	by	ADP
admet-2088	107	16	a	a	DET
admet-2088	107	17	sudden	sudden	ADJ
admet-2088	107	18	increase	increase	NOUN
admet-2088	107	19	in	in	ADP
admet-2088	107	20	angiogenic	angiogenic	ADJ
admet-2088	107	21	factors	factor	NOUN
admet-2088	107	22	.	.	PUNCT
admet-2088	108	1	therefore	therefore	ADV
admet-2088	108	2	,	,	PUNCT
admet-2088	108	3	the	the	DET
admet-2088	108	4	prognosis	prognosis	NOUN
admet-2088	108	5	of	of	ADP
admet-2088	108	6	melanoma	melanoma	NOUN
admet-2088	108	7	is	be	AUX
admet-2088	108	8	based	base	VERB
admet-2088	108	9	on	on	ADP
admet-2088	108	10	the	the	DET
admet-2088	108	11	stage	stage	NOUN
admet-2088	108	12	of	of	ADP
admet-2088	108	13	its	its	PRON
admet-2088	108	14	progression	progression	NOUN
admet-2088	108	15	.	.	PUNCT
admet-2088	109	1	the	the	DET
admet-2088	109	2	standard	standard	ADJ
admet-2088	109	3	treatment	treatment	NOUN
admet-2088	109	4	options	option	NOUN
admet-2088	109	5	available	available	ADJ
admet-2088	109	6	are	be	AUX
admet-2088	109	7	(	(	PUNCT
admet-2088	109	8	i	i	NOUN
admet-2088	109	9	)	)	PUNCT
admet-2088	109	10	surgical	surgical	ADJ
admet-2088	109	11	resection	resection	NOUN
admet-2088	109	12	,	,	PUNCT
admet-2088	109	13	(	(	PUNCT
admet-2088	109	14	ii	ii	NOUN
admet-2088	109	15	)	)	PUNCT
admet-2088	109	16	chemotherapy	chemotherapy	NOUN
admet-2088	109	17	(	(	PUNCT
admet-2088	109	18	using	use	VERB
admet-2088	109	19	chemotherapeutic	chemotherapeutic	ADJ
admet-2088	109	20	agents	agent	NOUN
admet-2088	109	21	)	)	PUNCT
admet-2088	109	22	,	,	PUNCT
admet-2088	109	23	(	(	PUNCT
admet-2088	109	24	iii	iii	NOUN
admet-2088	109	25	)	)	PUNCT
admet-2088	109	26	targeted	target	VERB
admet-2088	109	27	therapy	therapy	NOUN
admet-2088	109	28	(	(	PUNCT
admet-2088	109	29	oncogene	oncogene	NOUN
admet-2088	109	30	targeting	target	VERB
admet-2088	109	31	via	via	ADP
admet-2088	109	32	melanoma	melanoma	NOUN
admet-2088	109	33	signalling	signal	VERB
admet-2088	109	34	pathway	pathway	NOUN
admet-2088	109	35	inhibitors	inhibitor	NOUN
admet-2088	109	36	)	)	PUNCT
admet-2088	109	37	,	,	PUNCT
admet-2088	109	38	(	(	PUNCT
admet-2088	109	39	iv	iv	X
admet-2088	109	40	)	)	PUNCT
admet-2088	109	41	immunotherapy	immunotherapy	NOUN
admet-2088	109	42	(	(	PUNCT
admet-2088	109	43	immune	immune	ADJ
admet-2088	109	44	checkpoint	checkpoint	NOUN
admet-2088	109	45	inhibitors	inhibitor	NOUN
admet-2088	109	46	)	)	PUNCT
admet-2088	109	47	,	,	PUNCT
admet-2088	109	48	(	(	PUNCT
admet-2088	109	49	v	v	NOUN
admet-2088	109	50	)	)	PUNCT
admet-2088	109	51	radiation	radiation	NOUN
admet-2088	109	52	therapy	therapy	NOUN
admet-2088	109	53	(	(	PUNCT
admet-2088	109	54	vi	vi	NOUN
admet-2088	109	55	)	)	PUNCT
admet-2088	109	56	pdt	pdt	NOUN
admet-2088	109	57	and	and	CCONJ
admet-2088	109	58	(	(	PUNCT
admet-2088	109	59	vii	vii	PROPN
admet-2088	109	60	)	)	PUNCT
admet-2088	109	61	ptt	ptt	PROPN
admet-2088	109	62	.	.	PUNCT
admet-2088	110	1	i.	i.	PROPN
admet-2088	110	2	surgical	surgical	ADJ
admet-2088	110	3	resection	resection	NOUN
admet-2088	110	4	:	:	PUNCT
admet-2088	110	5	this	this	DET
admet-2088	110	6	option	option	NOUN
admet-2088	110	7	is	be	AUX
admet-2088	110	8	adopted	adopt	VERB
admet-2088	110	9	for	for	ADP
admet-2088	110	10	patients	patient	NOUN
admet-2088	110	11	with	with	ADP
admet-2088	110	12	stage	stage	NOUN
admet-2088	110	13	i	i	PRON
admet-2088	110	14	and	and	CCONJ
admet-2088	110	15	stage	stage	PROPN
admet-2088	110	16	ii	ii	PROPN
admet-2088	110	17	melanoma	melanoma	NOUN
admet-2088	110	18	lesions	lesion	NOUN
admet-2088	110	19	.	.	PUNCT
admet-2088	111	1	the	the	DET
admet-2088	111	2	5year	5year	NUM
admet-2088	111	3	survival	survival	NOUN
admet-2088	111	4	rate	rate	NOUN
admet-2088	111	5	for	for	ADP
admet-2088	111	6	surgical	surgical	ADJ
admet-2088	111	7	resection	resection	NOUN
admet-2088	111	8	is	be	AUX
admet-2088	111	9	95	95	NUM
admet-2088	111	10	and	and	CCONJ
admet-2088	111	11	80	80	NUM
admet-2088	111	12	%	%	NOUN
admet-2088	111	13	with	with	ADP
admet-2088	111	14	stage	stage	NOUN
admet-2088	111	15	i	i	PRON
admet-2088	111	16	and	and	CCONJ
admet-2088	111	17	stage	stage	PROPN
admet-2088	111	18	ii	ii	PROPN
admet-2088	111	19	melanoma	melanoma	NOUN
admet-2088	111	20	,	,	PUNCT
admet-2088	111	21	respectively	respectively	ADV
admet-2088	111	22	[	[	X
admet-2088	111	23	46	46	NUM
admet-2088	111	24	]	]	PUNCT
admet-2088	111	25	.	.	PUNCT
admet-2088	112	1	generally	generally	ADV
admet-2088	112	2	,	,	PUNCT
admet-2088	112	3	moh	moh	PROPN
admet-2088	112	4	’s	’s	PART
admet-2088	112	5	surgery	surgery	NOUN
admet-2088	112	6	is	be	AUX
admet-2088	112	7	employed	employ	VERB
admet-2088	112	8	to	to	PART
admet-2088	112	9	excise	excise	VERB
admet-2088	112	10	layers	layer	NOUN
admet-2088	112	11	of	of	ADP
admet-2088	112	12	skin	skin	NOUN
admet-2088	112	13	until	until	SCONJ
admet-2088	112	14	there	there	PRON
admet-2088	112	15	is	be	VERB
admet-2088	112	16	no	no	DET
admet-2088	112	17	sign	sign	NOUN
admet-2088	112	18	of	of	ADP
admet-2088	112	19	a	a	DET
admet-2088	112	20	tumour	tumour	NOUN
admet-2088	112	21	,	,	PUNCT
admet-2088	112	22	but	but	CCONJ
admet-2088	112	23	in	in	ADP
admet-2088	112	24	some	some	DET
admet-2088	112	25	instances	instance	NOUN
admet-2088	112	26	,	,	PUNCT
admet-2088	112	27	lymphadenectomy	lymphadenectomy	NOUN
admet-2088	112	28	or	or	CCONJ
admet-2088	112	29	amputation	amputation	NOUN
admet-2088	112	30	is	be	AUX
admet-2088	112	31	essential	essential	ADJ
admet-2088	112	32	[	[	X
admet-2088	112	33	12,47	12,47	NUM
admet-2088	112	34	]	]	X
admet-2088	112	35	.	.	PUNCT
admet-2088	113	1	however	however	ADV
admet-2088	113	2	,	,	PUNCT
admet-2088	113	3	surgical	surgical	ADJ
admet-2088	113	4	resection	resection	NOUN
admet-2088	113	5	is	be	AUX
admet-2088	113	6	not	not	PART
admet-2088	113	7	a	a	DET
admet-2088	113	8	feasible	feasible	ADJ
admet-2088	113	9	option	option	NOUN
admet-2088	113	10	for	for	ADP
admet-2088	113	11	melanoma	melanoma	NOUN
admet-2088	113	12	after	after	SCONJ
admet-2088	113	13	metastasis	metastasis	NOUN
admet-2088	113	14	into	into	ADP
admet-2088	113	15	distant	distant	ADJ
admet-2088	113	16	organs	organ	NOUN
admet-2088	113	17	(	(	PUNCT
admet-2088	113	18	stage	stage	NOUN
admet-2088	113	19	iv	iv	NUM
admet-2088	113	20	)	)	PUNCT
admet-2088	113	21	as	as	ADP
admet-2088	113	22	the	the	DET
admet-2088	113	23	median	median	ADJ
admet-2088	113	24	survival	survival	NOUN
admet-2088	113	25	of	of	ADP
admet-2088	113	26	only	only	ADV
admet-2088	113	27	8	8	NUM
admet-2088	113	28	-	-	SYM
admet-2088	113	29	9	9	NUM
admet-2088	113	30	months	month	NOUN
admet-2088	113	31	and	and	CCONJ
admet-2088	113	32	the	the	DET
admet-2088	113	33	3	3	NUM
admet-2088	113	34	-	-	PUNCT
admet-2088	113	35	year	year	NOUN
admet-2088	113	36	overall	overall	ADJ
admet-2088	113	37	survival	survival	NOUN
admet-2088	113	38	(	(	PUNCT
admet-2088	113	39	os	os	NOUN
admet-2088	113	40	)	)	PUNCT
admet-2088	113	41	rate	rate	NOUN
admet-2088	113	42	is	be	AUX
admet-2088	113	43	lower	low	ADJ
admet-2088	113	44	than	than	ADP
admet-2088	113	45	15	15	NUM
admet-2088	113	46	%	%	NOUN
admet-2088	113	47	[	[	X
admet-2088	113	48	48	48	NUM
admet-2088	113	49	]	]	PUNCT
admet-2088	113	50	.	.	PUNCT
admet-2088	114	1	thus	thus	ADV
admet-2088	114	2	,	,	PUNCT
admet-2088	114	3	in	in	ADP
admet-2088	114	4	the	the	DET
admet-2088	114	5	case	case	NOUN
admet-2088	114	6	of	of	ADP
admet-2088	114	7	non	non	ADJ
admet-2088	114	8	-	-	ADJ
admet-2088	114	9	respectable	respectable	ADJ
admet-2088	114	10	melanoma	melanoma	NOUN
admet-2088	114	11	/	/	SYM
admet-2088	114	12	metastatic	metastatic	ADJ
admet-2088	114	13	melanoma	melanoma	NOUN
admet-2088	114	14	,	,	PUNCT
admet-2088	114	15	other	other	ADJ
admet-2088	114	16	treatment	treatment	NOUN
admet-2088	114	17	options	option	NOUN
admet-2088	114	18	are	be	AUX
admet-2088	114	19	being	be	AUX
admet-2088	114	20	widely	widely	ADV
admet-2088	114	21	used	use	VERB
admet-2088	114	22	.	.	PUNCT
admet-2088	115	1	ii	ii	X
admet-2088	115	2	.	.	PUNCT
admet-2088	116	1	chemotherapy	chemotherapy	NOUN
admet-2088	116	2	:	:	PUNCT
admet-2088	117	1	treatment	treatment	NOUN
admet-2088	117	2	of	of	ADP
admet-2088	117	3	melanoma	melanoma	NOUN
admet-2088	117	4	chemotherapeutic	chemotherapeutic	ADJ
admet-2088	117	5	agents	agent	NOUN
admet-2088	117	6	involves	involve	VERB
admet-2088	117	7	the	the	DET
admet-2088	117	8	use	use	NOUN
admet-2088	117	9	of	of	ADP
admet-2088	117	10	fda	fda	PROPN
admet-2088	117	11	-	-	PUNCT
admet-2088	117	12	approved	approve	VERB
admet-2088	117	13	dacarbazine	dacarbazine	NOUN
admet-2088	117	14	,	,	PUNCT
admet-2088	117	15	high	high	ADV
admet-2088	117	16	-	-	PUNCT
admet-2088	117	17	dose	dose	NOUN
admet-2088	117	18	of	of	ADP
admet-2088	117	19	interleukin-2	interleukin-2	NOUN
admet-2088	117	20	(	(	PUNCT
admet-2088	117	21	il-2	il-2	NUM
admet-2088	117	22	)	)	PUNCT
admet-2088	117	23	and	and	CCONJ
admet-2088	117	24	interferon	interferon	PROPN
admet-2088	117	25	α-2b	α-2b	PROPN
admet-2088	117	26	(	(	PUNCT
admet-2088	117	27	ifn	ifn	PROPN
admet-2088	117	28	-	-	PUNCT
admet-2088	117	29	a-2b	a-2b	NOUN
admet-2088	117	30	)	)	PUNCT
admet-2088	118	1	[	[	X
admet-2088	118	2	29,40	29,40	NUM
admet-2088	118	3	]	]	PUNCT
admet-2088	118	4	.	.	PUNCT
admet-2088	119	1	in	in	ADP
admet-2088	119	2	addition	addition	NOUN
admet-2088	119	3	,	,	PUNCT
admet-2088	119	4	some	some	DET
admet-2088	119	5	natural	natural	ADJ
admet-2088	119	6	bioactive	bioactive	ADJ
admet-2088	119	7	compounds	compound	NOUN
admet-2088	119	8	such	such	ADJ
admet-2088	119	9	as	as	ADP
admet-2088	119	10	taxanes	taxane	NOUN
admet-2088	119	11	(	(	PUNCT
admet-2088	119	12	taxol	taxol	PROPN
admet-2088	119	13	,	,	PUNCT
admet-2088	119	14	docetaxel	docetaxel	NOUN
admet-2088	119	15	)	)	PUNCT
admet-2088	119	16	and	and	CCONJ
admet-2088	119	17	vinca	vinca	NOUN
admet-2088	119	18	alkaloids	alkaloid	NOUN
admet-2088	119	19	(	(	PUNCT
admet-2088	119	20	vincristine	vincristine	NOUN
admet-2088	119	21	and	and	CCONJ
admet-2088	119	22	vinblastine	vinblastine	NOUN
admet-2088	119	23	)	)	PUNCT
admet-2088	119	24	are	be	AUX
admet-2088	119	25	also	also	ADV
admet-2088	119	26	being	be	AUX
admet-2088	119	27	considered	consider	VERB
admet-2088	119	28	for	for	ADP
admet-2088	119	29	melanoma	melanoma	NOUN
admet-2088	119	30	treatment	treatment	NOUN
admet-2088	119	31	.	.	PUNCT
admet-2088	120	1	however	however	ADV
admet-2088	120	2	,	,	PUNCT
admet-2088	120	3	the	the	DET
admet-2088	120	4	overall	overall	ADJ
admet-2088	120	5	objective	objective	ADJ
admet-2088	120	6	response	response	NOUN
admet-2088	120	7	rates	rate	NOUN
admet-2088	120	8	were	be	AUX
admet-2088	120	9	20	20	NUM
admet-2088	120	10	,	,	PUNCT
admet-2088	120	11	16	16	NUM
admet-2088	120	12	and	and	CCONJ
admet-2088	120	13	15	15	NUM
admet-2088	120	14	%	%	NOUN
admet-2088	120	15	for	for	ADP
admet-2088	120	16	dacarbazine	dacarbazine	NOUN
admet-2088	120	17	,	,	PUNCT
admet-2088	120	18	high	high	ADV
admet-2088	120	19	-	-	PUNCT
admet-2088	120	20	dose	dose	NOUN
admet-2088	120	21	of	of	ADP
admet-2088	120	22	il-2	il-2	PROPN
admet-2088	120	23	and	and	CCONJ
admet-2088	120	24	ifn	ifn	PROPN
admet-2088	120	25	-	-	PUNCT
admet-2088	120	26	a-2b	a-2b	NOUN
admet-2088	120	27	)	)	PUNCT
admet-2088	120	28	,	,	PUNCT
admet-2088	120	29	respectively	respectively	ADV
admet-2088	120	30	[	[	X
admet-2088	120	31	49	49	NUM
admet-2088	120	32	]	]	PUNCT
admet-2088	120	33	.	.	PUNCT
admet-2088	121	1	furthermore	furthermore	ADV
admet-2088	121	2	,	,	PUNCT
admet-2088	121	3	the	the	DET
admet-2088	121	4	non	non	ADJ
admet-2088	121	5	-	-	ADJ
admet-2088	121	6	selective	selective	ADJ
admet-2088	121	7	killing	killing	NOUN
admet-2088	121	8	of	of	ADP
admet-2088	121	9	cells	cell	NOUN
admet-2088	121	10	involving	involve	VERB
admet-2088	121	11	the	the	DET
admet-2088	121	12	killing	killing	NOUN
admet-2088	121	13	of	of	ADP
admet-2088	121	14	healthy	healthy	ADJ
admet-2088	121	15	cells	cell	NOUN
admet-2088	121	16	takes	take	VERB
admet-2088	121	17	place	place	NOUN
admet-2088	121	18	and	and	CCONJ
admet-2088	121	19	the	the	DET
admet-2088	121	20	resistance	resistance	NOUN
admet-2088	121	21	to	to	ADP
admet-2088	121	22	the	the	DET
admet-2088	121	23	treatment	treatment	NOUN
admet-2088	121	24	with	with	ADP
admet-2088	121	25	a	a	DET
admet-2088	121	26	median	median	ADJ
admet-2088	121	27	response	response	NOUN
admet-2088	121	28	time	time	NOUN
admet-2088	121	29	between	between	ADP
admet-2088	121	30	4	4	NUM
admet-2088	121	31	-	-	SYM
admet-2088	121	32	6	6	NUM
admet-2088	121	33	months	month	NOUN
admet-2088	121	34	has	have	AUX
admet-2088	121	35	been	be	AUX
admet-2088	121	36	developed	develop	VERB
admet-2088	121	37	by	by	ADP
admet-2088	121	38	melanoma	melanoma	NOUN
admet-2088	121	39	[	[	X
admet-2088	121	40	50	50	NUM
admet-2088	121	41	]	]	PUNCT
admet-2088	121	42	.	.	PUNCT
admet-2088	122	1	iii	iii	X
admet-2088	122	2	.	.	PUNCT
admet-2088	122	3	targeted	target	VERB
admet-2088	122	4	therapy	therapy	NOUN
admet-2088	122	5	:	:	PUNCT
admet-2088	122	6	recently	recently	ADV
admet-2088	122	7	,	,	PUNCT
admet-2088	122	8	the	the	DET
admet-2088	122	9	treatment	treatment	NOUN
admet-2088	122	10	of	of	ADP
admet-2088	122	11	metastatic	metastatic	ADJ
admet-2088	122	12	melanoma	melanoma	NOUN
admet-2088	122	13	has	have	AUX
admet-2088	122	14	been	be	AUX
admet-2088	122	15	majorly	majorly	ADV
admet-2088	122	16	focussed	focusse	VERB
admet-2088	122	17	on	on	ADP
admet-2088	122	18	underlying	underlie	VERB
admet-2088	122	19	genetic	genetic	ADJ
admet-2088	122	20	mutation	mutation	NOUN
admet-2088	122	21	and	and	CCONJ
admet-2088	122	22	immunological	immunological	ADJ
admet-2088	122	23	factors	factor	NOUN
admet-2088	122	24	.	.	PUNCT
admet-2088	123	1	the	the	DET
admet-2088	123	2	braf	braf	NOUN
admet-2088	123	3	inhibitors	inhibitor	NOUN
admet-2088	123	4	(	(	PUNCT
admet-2088	123	5	functioning	function	VERB
admet-2088	123	6	through	through	ADP
admet-2088	123	7	mapk	mapk	NOUN
admet-2088	123	8	signalling	signal	VERB
admet-2088	123	9	pathway	pathway	NOUN
admet-2088	123	10	and	and	CCONJ
admet-2088	123	11	inhibiting	inhibit	VERB
admet-2088	123	12	braf	braf	NOUN
admet-2088	123	13	protein	protein	NOUN
admet-2088	123	14	synthesis	synthesis	NOUN
admet-2088	123	15	)	)	PUNCT
admet-2088	123	16	such	such	ADJ
admet-2088	123	17	as	as	ADP
admet-2088	123	18	vemurafenib	vemurafenib	NOUN
admet-2088	123	19	dabrafenib	dabrafenib	NOUN
admet-2088	123	20	and	and	CCONJ
admet-2088	123	21	encorafenib	encorafenib	NOUN
admet-2088	123	22	,	,	PUNCT
admet-2088	123	23	mek	mek	PROPN
admet-2088	123	24	inhibitors	inhibitor	NOUN
admet-2088	123	25	such	such	ADJ
admet-2088	123	26	as	as	ADP
admet-2088	123	27	trametinib	trametinib	NOUN
admet-2088	123	28	,	,	PUNCT
admet-2088	123	29	binimetinib	binimetinib	NOUN
admet-2088	123	30	and	and	CCONJ
admet-2088	123	31	cobimetinib	cobimetinib	NOUN
admet-2088	123	32	and	and	CCONJ
admet-2088	123	33	c	c	NOUN
admet-2088	123	34	-	-	PUNCT
admet-2088	123	35	kit	kit	NOUN
admet-2088	123	36	inhibitors	inhibitor	NOUN
admet-2088	123	37	(	(	PUNCT
admet-2088	123	38	e.g.	e.g.	ADV
admet-2088	123	39	,	,	PUNCT
admet-2088	123	40	imatinib	imatinib	NOUN
admet-2088	123	41	,	,	PUNCT
admet-2088	123	42	nilotinib	nilotinib	NOUN
admet-2088	123	43	)	)	PUNCT
admet-2088	123	44	showed	show	VERB
admet-2088	123	45	initial	initial	ADJ
admet-2088	123	46	superior	superior	ADJ
admet-2088	123	47	response	response	NOUN
admet-2088	123	48	than	than	ADP
admet-2088	123	49	that	that	PRON
admet-2088	123	50	of	of	ADP
admet-2088	123	51	dacarbazine	dacarbazine	NOUN
admet-2088	123	52	and	and	CCONJ
admet-2088	123	53	improvement	improvement	NOUN
admet-2088	123	54	on	on	ADP
admet-2088	123	55	the	the	DET
admet-2088	123	56	progression	progression	NOUN
admet-2088	123	57	-	-	PUNCT
admet-2088	123	58	free	free	ADJ
admet-2088	123	59	survival	survival	NOUN
admet-2088	123	60	and	and	CCONJ
admet-2088	123	61	os	os	NOUN
admet-2088	123	62	.	.	PUNCT
admet-2088	124	1	however	however	ADV
admet-2088	124	2	,	,	PUNCT
admet-2088	124	3	braf	braf	NOUN
admet-2088	124	4	inhibitor	inhibitor	NOUN
admet-2088	124	5	sufferers	sufferer	NOUN
admet-2088	124	6	have	have	VERB
admet-2088	124	7	a	a	DET
admet-2088	124	8	high	high	ADJ
admet-2088	124	9	relapse	relapse	NOUN
admet-2088	124	10	rate	rate	NOUN
admet-2088	124	11	due	due	ADP
admet-2088	124	12	to	to	ADP
admet-2088	124	13	resistance	resistance	NOUN
admet-2088	124	14	after	after	ADP
admet-2088	124	15	6	6	NUM
admet-2088	124	16	months	month	NOUN
admet-2088	124	17	and	and	CCONJ
admet-2088	124	18	show	show	VERB
admet-2088	124	19	adverse	adverse	ADJ
admet-2088	124	20	effects	effect	NOUN
admet-2088	124	21	[	[	X
admet-2088	124	22	40,51,52	40,51,52	NUM
admet-2088	124	23	]	]	PUNCT
admet-2088	124	24	.	.	PUNCT
admet-2088	125	1	iv	iv	X
admet-2088	125	2	.	.	PUNCT
admet-2088	125	3	immunotherapy	immunotherapy	NOUN
admet-2088	125	4	involves	involve	VERB
admet-2088	125	5	the	the	DET
admet-2088	125	6	increase	increase	NOUN
admet-2088	125	7	in	in	ADP
admet-2088	125	8	the	the	DET
admet-2088	125	9	immune	immune	ADJ
admet-2088	125	10	system	system	NOUN
admet-2088	125	11	to	to	PART
admet-2088	125	12	actively	actively	ADV
admet-2088	125	13	or	or	CCONJ
admet-2088	125	14	passively	passively	ADV
admet-2088	125	15	fight	fight	VERB
admet-2088	125	16	against	against	ADP
admet-2088	125	17	melanoma	melanoma	NOUN
admet-2088	125	18	[	[	X
admet-2088	125	19	47	47	NUM
admet-2088	125	20	]	]	PUNCT
admet-2088	125	21	.	.	PUNCT
admet-2088	126	1	it	it	PRON
admet-2088	126	2	involves	involve	VERB
admet-2088	126	3	immune	immune	ADJ
admet-2088	126	4	checkpoint	checkpoint	NOUN
admet-2088	126	5	inhibitors	inhibitor	NOUN
admet-2088	126	6	such	such	ADJ
admet-2088	126	7	as	as	ADP
admet-2088	126	8	ipilimumab	ipilimumab	NOUN
admet-2088	126	9	,	,	PUNCT
admet-2088	126	10	and	and	CCONJ
admet-2088	126	11	inhibition	inhibition	NOUN
admet-2088	126	12	of	of	ADP
admet-2088	126	13	an	an	DET
admet-2088	126	14	antictla-4	antictla-4	NOUN
admet-2088	126	15	mab	mab	NOUN
admet-2088	126	16	such	such	ADJ
admet-2088	126	17	as	as	ADP
admet-2088	126	18	atezolizumab	atezolizumab	NOUN
admet-2088	126	19	,	,	PUNCT
admet-2088	126	20	avelumab	avelumab	ADJ
admet-2088	126	21	,	,	PUNCT
admet-2088	126	22	ipilimumab	ipilimumab	ADJ
admet-2088	126	23	and	and	CCONJ
admet-2088	126	24	anti	anti	ADJ
admet-2088	126	25	-	-	NOUN
admet-2088	126	26	pd-1	pd-1	ADV
admet-2088	126	27	such	such	ADJ
admet-2088	126	28	as	as	ADP
admet-2088	126	29	nivolumab	nivolumab	NOUN
admet-2088	126	30	and	and	CCONJ
admet-2088	126	31	pembrolizumab	pembrolizumab	NOUN
admet-2088	126	32	antagonising	antagonise	VERB
admet-2088	126	33	the	the	DET
admet-2088	126	34	activity	activity	NOUN
admet-2088	126	35	of	of	ADP
admet-2088	126	36	pd-1	pd-1	ADV
admet-2088	126	37	demonstrated	demonstrate	VERB
admet-2088	126	38	more	more	ADV
admet-2088	126	39	durable	durable	ADJ
admet-2088	126	40	responses	response	NOUN
admet-2088	126	41	with	with	ADP
admet-2088	126	42	only	only	ADV
admet-2088	126	43	a	a	DET
admet-2088	126	44	small	small	ADJ
admet-2088	126	45	portion	portion	NOUN
admet-2088	126	46	of	of	ADP
admet-2088	126	47	patients	patient	NOUN
admet-2088	126	48	achieve	achieve	VERB
admet-2088	126	49	an	an	DET
admet-2088	126	50	objective	objective	ADJ
admet-2088	126	51	response	response	NOUN
admet-2088	126	52	to	to	ADP
admet-2088	126	53	the	the	DET
admet-2088	126	54	treatment	treatment	NOUN
admet-2088	126	55	.	.	PUNCT
admet-2088	127	1	in	in	ADP
admet-2088	127	2	addition	addition	NOUN
admet-2088	127	3	,	,	PUNCT
admet-2088	127	4	the	the	DET
admet-2088	127	5	application	application	NOUN
admet-2088	127	6	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	127	7	m.	m.	NOUN
admet-2088	127	8	kulkarni	kulkarni	PROPN
admet-2088	127	9	et	et	PROPN
admet-2088	127	10	al	al	PROPN
admet-2088	127	11	.	.	PROPN
admet-2088	127	12	admet	admet	PROPN
admet-2088	127	13	&	&	CCONJ
admet-2088	127	14	dmpk	dmpk	PROPN
admet-2088	127	15	12(1	12(1	PROPN
admet-2088	127	16	)	)	PUNCT
admet-2088	127	17	(	(	PUNCT
admet-2088	127	18	2024	2024	NUM
admet-2088	127	19	)	)	PUNCT
admet-2088	127	20	107	107	NUM
admet-2088	127	21	-	-	SYM
admet-2088	127	22	150	150	NUM
admet-2088	127	23	112	112	NUM
admet-2088	127	24	of	of	ADP
admet-2088	127	25	immune	immune	ADJ
admet-2088	127	26	checkpoint	checkpoint	NOUN
admet-2088	127	27	inhibitors	inhibitor	NOUN
admet-2088	127	28	is	be	AUX
admet-2088	127	29	limited	limit	VERB
admet-2088	127	30	by	by	ADP
admet-2088	127	31	different	different	ADJ
admet-2088	127	32	immuno	immuno	ADJ
admet-2088	127	33	-	-	PUNCT
admet-2088	127	34	related	relate	VERB
admet-2088	127	35	adverse	adverse	ADJ
admet-2088	127	36	effects	effect	NOUN
admet-2088	127	37	such	such	ADJ
admet-2088	127	38	as	as	ADP
admet-2088	127	39	nephritis	nephritis	NOUN
admet-2088	127	40	,	,	PUNCT
admet-2088	127	41	colitis	colitis	NOUN
admet-2088	127	42	,	,	PUNCT
admet-2088	127	43	hepatitis	hepatitis	NOUN
admet-2088	127	44	,	,	PUNCT
admet-2088	127	45	cardiotoxicity	cardiotoxicity	PROPN
admet-2088	127	46	,	,	PUNCT
admet-2088	127	47	vitiligo	vitiligo	NOUN
admet-2088	127	48	,	,	PUNCT
admet-2088	127	49	pruritis	pruritis	NOUN
admet-2088	127	50	,	,	PUNCT
admet-2088	127	51	etc	etc	X
admet-2088	127	52	.	.	PUNCT
admet-2088	128	1	[	[	X
admet-2088	128	2	53,54	53,54	NUM
admet-2088	128	3	]	]	X
admet-2088	128	4	.	.	PUNCT
admet-2088	129	1	furthermore	furthermore	ADV
admet-2088	129	2	,	,	PUNCT
admet-2088	129	3	immune	immune	NOUN
admet-2088	129	4	-	-	PUNCT
admet-2088	129	5	related	relate	VERB
admet-2088	129	6	adverse	adverse	ADJ
admet-2088	129	7	effects	effect	NOUN
admet-2088	129	8	with	with	ADP
admet-2088	129	9	the	the	DET
admet-2088	129	10	blockade	blockade	NOUN
admet-2088	129	11	of	of	ADP
admet-2088	129	12	pd-1	pd-1	NOUN
admet-2088	129	13	limit	limit	VERB
admet-2088	129	14	their	their	PRON
admet-2088	129	15	clinical	clinical	ADJ
admet-2088	129	16	significance	significance	NOUN
admet-2088	129	17	[	[	X
admet-2088	129	18	55,56	55,56	NOUN
admet-2088	129	19	]	]	PUNCT
admet-2088	129	20	.	.	PUNCT
admet-2088	130	1	v.	v.	ADP
admet-2088	130	2	radiation	radiation	NOUN
admet-2088	130	3	therapy	therapy	NOUN
admet-2088	130	4	involves	involve	VERB
admet-2088	130	5	the	the	DET
admet-2088	130	6	application	application	NOUN
admet-2088	130	7	of	of	ADP
admet-2088	130	8	high	high	ADJ
admet-2088	130	9	-	-	PUNCT
admet-2088	130	10	energy	energy	NOUN
admet-2088	130	11	electromagnetic	electromagnetic	ADJ
admet-2088	130	12	rays	ray	NOUN
admet-2088	130	13	such	such	ADJ
admet-2088	130	14	as	as	ADP
admet-2088	130	15	xand	xand	PROPN
admet-2088	130	16	-rays	-rays	PUNCT
admet-2088	130	17	for	for	ADP
admet-2088	130	18	the	the	DET
admet-2088	130	19	treatment	treatment	NOUN
admet-2088	130	20	of	of	ADP
admet-2088	130	21	melanoma	melanoma	NOUN
admet-2088	130	22	when	when	SCONJ
admet-2088	130	23	spread	spread	VERB
admet-2088	130	24	to	to	ADP
admet-2088	130	25	distal	distal	ADJ
admet-2088	130	26	organs	organ	NOUN
admet-2088	130	27	such	such	ADJ
admet-2088	130	28	as	as	ADP
admet-2088	130	29	the	the	DET
admet-2088	130	30	brain	brain	NOUN
admet-2088	130	31	,	,	PUNCT
admet-2088	130	32	bones	bone	NOUN
admet-2088	130	33	,	,	PUNCT
admet-2088	130	34	etc	etc	X
admet-2088	130	35	.	.	X
admet-2088	130	36	radiation	radiation	NOUN
admet-2088	130	37	selectively	selectively	ADV
admet-2088	130	38	causes	cause	VERB
admet-2088	130	39	neoplastic	neoplastic	ADJ
admet-2088	130	40	cell	cell	NOUN
admet-2088	130	41	killing	killing	NOUN
admet-2088	130	42	and	and	CCONJ
admet-2088	130	43	dna	dna	NOUN
admet-2088	130	44	damage	damage	NOUN
admet-2088	130	45	of	of	ADP
admet-2088	130	46	the	the	DET
admet-2088	130	47	malignant	malignant	ADJ
admet-2088	130	48	cells	cell	NOUN
admet-2088	130	49	that	that	PRON
admet-2088	130	50	prevent	prevent	VERB
admet-2088	130	51	these	these	DET
admet-2088	130	52	cells	cell	NOUN
admet-2088	130	53	from	from	ADP
admet-2088	130	54	multiplication	multiplication	NOUN
admet-2088	130	55	[	[	X
admet-2088	130	56	57	57	NUM
admet-2088	130	57	]	]	SYM
admet-2088	130	58	.	.	PUNCT
admet-2088	131	1	vi	vi	X
admet-2088	131	2	.	.	PROPN
admet-2088	131	3	pdt	pdt	PROPN
admet-2088	131	4	:	:	PUNCT
admet-2088	131	5	this	this	DET
admet-2088	131	6	method	method	NOUN
admet-2088	131	7	of	of	ADP
admet-2088	131	8	melanoma	melanoma	NOUN
admet-2088	131	9	treatment	treatment	NOUN
admet-2088	131	10	employs	employ	VERB
admet-2088	131	11	light	light	ADJ
admet-2088	131	12	,	,	PUNCT
admet-2088	131	13	photosensitizer	photosensitizer	NOUN
admet-2088	131	14	and	and	CCONJ
admet-2088	131	15	oxygen	oxygen	NOUN
admet-2088	131	16	to	to	PART
admet-2088	131	17	generate	generate	VERB
admet-2088	131	18	reactive	reactive	ADJ
admet-2088	131	19	oxygen	oxygen	NOUN
admet-2088	131	20	species	specie	NOUN
admet-2088	131	21	(	(	PUNCT
admet-2088	131	22	ros	ros	PROPN
admet-2088	131	23	)	)	PUNCT
admet-2088	131	24	,	,	PUNCT
admet-2088	131	25	such	such	ADJ
admet-2088	131	26	as	as	ADP
admet-2088	131	27	singlet	singlet	ADJ
admet-2088	131	28	oxygen	oxygen	NOUN
admet-2088	131	29	,	,	PUNCT
admet-2088	131	30	against	against	ADP
admet-2088	131	31	melanoma	melanoma	NOUN
admet-2088	131	32	cells	cell	NOUN
admet-2088	131	33	[	[	X
admet-2088	131	34	58,59	58,59	X
admet-2088	131	35	]	]	PUNCT
admet-2088	131	36	.	.	PUNCT
admet-2088	132	1	here	here	ADV
admet-2088	132	2	,	,	PUNCT
admet-2088	132	3	the	the	DET
admet-2088	132	4	light	light	NOUN
admet-2088	132	5	is	be	AUX
admet-2088	132	6	absorbed	absorb	VERB
admet-2088	132	7	by	by	ADP
admet-2088	132	8	photosensitizer	photosensitizer	NOUN
admet-2088	132	9	and	and	CCONJ
admet-2088	132	10	the	the	DET
admet-2088	132	11	light	light	ADJ
admet-2088	132	12	energy	energy	NOUN
admet-2088	132	13	is	be	AUX
admet-2088	132	14	stored	store	VERB
admet-2088	132	15	in	in	ADP
admet-2088	132	16	the	the	DET
admet-2088	132	17	singlet	singlet	NOUN
admet-2088	132	18	or	or	CCONJ
admet-2088	132	19	triplet	triplet	NOUN
admet-2088	132	20	state	state	NOUN
admet-2088	132	21	of	of	ADP
admet-2088	132	22	the	the	DET
admet-2088	132	23	sensitizer	sensitizer	NOUN
admet-2088	132	24	molecules	molecule	NOUN
admet-2088	132	25	.	.	PUNCT
admet-2088	133	1	in	in	ADP
admet-2088	133	2	the	the	DET
admet-2088	133	3	singlet	singlet	ADJ
admet-2088	133	4	state	state	NOUN
admet-2088	133	5	,	,	PUNCT
admet-2088	133	6	the	the	DET
admet-2088	133	7	energy	energy	NOUN
admet-2088	133	8	is	be	AUX
admet-2088	133	9	converted	convert	VERB
admet-2088	133	10	into	into	ADP
admet-2088	133	11	heat	heat	NOUN
admet-2088	133	12	or	or	CCONJ
admet-2088	133	13	emitted	emit	VERB
admet-2088	133	14	as	as	ADP
admet-2088	133	15	light	light	NOUN
admet-2088	133	16	,	,	PUNCT
admet-2088	133	17	while	while	SCONJ
admet-2088	133	18	the	the	DET
admet-2088	133	19	triplet	triplet	NOUN
admet-2088	133	20	state	state	NOUN
admet-2088	133	21	generates	generate	VERB
admet-2088	133	22	ros	ros	PROPN
admet-2088	133	23	for	for	ADP
admet-2088	133	24	the	the	DET
admet-2088	133	25	successful	successful	ADJ
admet-2088	133	26	pdt	pdt	NOUN
admet-2088	133	27	.	.	PUNCT
admet-2088	134	1	these	these	DET
admet-2088	134	2	ros	ros	PROPN
admet-2088	134	3	cause	cause	VERB
admet-2088	134	4	apoptosis	apoptosis	NOUN
admet-2088	134	5	and	and	CCONJ
admet-2088	134	6	necrosis	necrosis	NOUN
admet-2088	134	7	of	of	ADP
admet-2088	134	8	cancer	cancer	NOUN
admet-2088	134	9	cells	cell	NOUN
admet-2088	134	10	.	.	PUNCT
admet-2088	135	1	pdt	pdt	PROPN
admet-2088	135	2	is	be	AUX
admet-2088	135	3	a	a	DET
admet-2088	135	4	non	non	ADJ
admet-2088	135	5	-	-	ADJ
admet-2088	135	6	invasive	invasive	ADJ
admet-2088	135	7	and	and	CCONJ
admet-2088	135	8	inexpensive	inexpensive	ADJ
admet-2088	135	9	method	method	NOUN
admet-2088	135	10	that	that	PRON
admet-2088	135	11	requires	require	VERB
admet-2088	135	12	proper	proper	ADJ
admet-2088	135	13	coordination	coordination	NOUN
admet-2088	135	14	between	between	ADP
admet-2088	135	15	light	light	ADJ
admet-2088	135	16	sources	source	NOUN
admet-2088	135	17	such	such	ADJ
admet-2088	135	18	as	as	ADP
admet-2088	135	19	lasers	laser	NOUN
admet-2088	135	20	,	,	PUNCT
admet-2088	135	21	light	light	NOUN
admet-2088	135	22	-	-	PUNCT
admet-2088	135	23	emitting	emit	VERB
admet-2088	135	24	diodes	diode	NOUN
admet-2088	135	25	(	(	PUNCT
admet-2088	135	26	leds	led	NOUN
admet-2088	135	27	)	)	PUNCT
admet-2088	135	28	and	and	CCONJ
admet-2088	135	29	photosensitizers	photosensitizer	NOUN
admet-2088	135	30	such	such	ADJ
admet-2088	135	31	as	as	ADP
admet-2088	135	32	inorganic	inorganic	ADJ
admet-2088	135	33	nms	nms	NOUN
admet-2088	135	34	such	such	ADJ
admet-2088	135	35	as	as	ADP
admet-2088	135	36	gold	gold	NOUN
admet-2088	135	37	,	,	PUNCT
admet-2088	135	38	platinum	platinum	NOUN
admet-2088	135	39	,	,	PUNCT
admet-2088	135	40	silver	silver	NOUN
admet-2088	135	41	,	,	PUNCT
admet-2088	135	42	etc	etc	X
admet-2088	135	43	.	.	X
admet-2088	136	1	vii	vii	PROPN
admet-2088	136	2	.	.	PUNCT
admet-2088	137	1	ptt	ptt	PROPN
admet-2088	137	2	is	be	AUX
admet-2088	137	3	based	base	VERB
admet-2088	137	4	on	on	ADP
admet-2088	137	5	the	the	DET
admet-2088	137	6	conversion	conversion	NOUN
admet-2088	137	7	of	of	ADP
admet-2088	137	8	photon	photon	NOUN
admet-2088	137	9	energy	energy	NOUN
admet-2088	137	10	into	into	ADP
admet-2088	137	11	heat	heat	NOUN
admet-2088	137	12	source	source	NOUN
admet-2088	137	13	by	by	ADP
admet-2088	137	14	the	the	DET
admet-2088	137	15	use	use	NOUN
admet-2088	137	16	of	of	ADP
admet-2088	137	17	photosensitizing	photosensitize	VERB
admet-2088	137	18	molecules	molecule	NOUN
admet-2088	137	19	to	to	PART
admet-2088	137	20	cause	cause	VERB
admet-2088	137	21	hyperthermia	hyperthermia	NOUN
admet-2088	137	22	and	and	CCONJ
admet-2088	137	23	subsequent	subsequent	ADJ
admet-2088	137	24	selective	selective	ADJ
admet-2088	137	25	killing	killing	NOUN
admet-2088	137	26	of	of	ADP
admet-2088	137	27	melanoma	melanoma	NOUN
admet-2088	137	28	cells	cell	NOUN
admet-2088	137	29	due	due	ADJ
admet-2088	137	30	to	to	AUX
admet-2088	137	31	heat	heat	VERB
admet-2088	137	32	[	[	NOUN
admet-2088	137	33	60	60	NUM
admet-2088	137	34	]	]	PUNCT
admet-2088	137	35	.	.	PUNCT
admet-2088	138	1	thus	thus	ADV
admet-2088	138	2	,	,	PUNCT
admet-2088	138	3	ptt	ptt	PROPN
admet-2088	138	4	is	be	AUX
admet-2088	138	5	a	a	DET
admet-2088	138	6	hyperthermic	hyperthermic	ADJ
admet-2088	138	7	treatment	treatment	NOUN
admet-2088	138	8	that	that	PRON
admet-2088	138	9	depends	depend	VERB
admet-2088	138	10	on	on	ADP
admet-2088	138	11	the	the	DET
admet-2088	138	12	ability	ability	NOUN
admet-2088	138	13	of	of	ADP
admet-2088	138	14	photosensitizing	photosensitize	VERB
admet-2088	138	15	molecules	molecule	NOUN
admet-2088	138	16	(	(	PUNCT
admet-2088	138	17	e.g.	e.g.	ADV
admet-2088	138	18	,	,	PUNCT
admet-2088	138	19	inorganic	inorganic	ADJ
admet-2088	138	20	nms	nms	NOUN
admet-2088	138	21	)	)	PUNCT
admet-2088	138	22	to	to	PART
admet-2088	138	23	absorb	absorb	VERB
admet-2088	138	24	laser	laser	NOUN
admet-2088	138	25	irradiation	irradiation	NOUN
admet-2088	138	26	and	and	CCONJ
admet-2088	138	27	convert	convert	VERB
admet-2088	138	28	them	they	PRON
admet-2088	138	29	into	into	ADP
admet-2088	138	30	heat	heat	NOUN
admet-2088	138	31	[	[	X
admet-2088	138	32	61	61	NUM
admet-2088	138	33	]	]	PUNCT
admet-2088	138	34	.	.	PUNCT
admet-2088	139	1	ptt	ptt	PROPN
admet-2088	139	2	is	be	AUX
admet-2088	139	3	a	a	DET
admet-2088	139	4	widely	widely	ADV
admet-2088	139	5	used	use	VERB
admet-2088	139	6	method	method	NOUN
admet-2088	139	7	in	in	ADP
admet-2088	139	8	association	association	NOUN
admet-2088	139	9	with	with	ADP
admet-2088	139	10	other	other	ADJ
admet-2088	139	11	therapies	therapy	NOUN
admet-2088	139	12	such	such	ADJ
admet-2088	139	13	as	as	ADP
admet-2088	139	14	chemotherapy	chemotherapy	NOUN
admet-2088	139	15	,	,	PUNCT
admet-2088	139	16	immunotherapy	immunotherapy	NOUN
admet-2088	139	17	and	and	CCONJ
admet-2088	139	18	even	even	ADV
admet-2088	139	19	pdt	pdt	VERB
admet-2088	139	20	for	for	ADP
admet-2088	139	21	better	well	ADJ
admet-2088	139	22	success	success	NOUN
admet-2088	139	23	in	in	ADP
admet-2088	139	24	the	the	DET
admet-2088	139	25	treatment	treatment	NOUN
admet-2088	139	26	of	of	ADP
admet-2088	139	27	melanoma	melanoma	NOUN
admet-2088	139	28	[	[	X
admet-2088	139	29	60	60	NUM
admet-2088	139	30	]	]	PUNCT
admet-2088	139	31	.	.	PUNCT
admet-2088	140	1	despite	despite	SCONJ
admet-2088	140	2	all	all	DET
admet-2088	140	3	the	the	DET
admet-2088	140	4	conventional	conventional	ADJ
admet-2088	140	5	treatment	treatment	NOUN
admet-2088	140	6	options	option	NOUN
admet-2088	140	7	,	,	PUNCT
admet-2088	140	8	there	there	PRON
admet-2088	140	9	is	be	VERB
admet-2088	140	10	inevitably	inevitably	ADV
admet-2088	140	11	low	low	ADJ
admet-2088	140	12	efficacy	efficacy	NOUN
admet-2088	140	13	and	and	CCONJ
admet-2088	140	14	adverse	adverse	ADJ
admet-2088	140	15	effects	effect	NOUN
admet-2088	140	16	due	due	ADJ
admet-2088	140	17	to	to	ADP
admet-2088	140	18	the	the	DET
admet-2088	140	19	non	non	ADJ
admet-2088	140	20	-	-	ADJ
admet-2088	140	21	specific	specific	ADJ
admet-2088	140	22	delivery	delivery	NOUN
admet-2088	140	23	of	of	ADP
admet-2088	140	24	therapeutic	therapeutic	ADJ
admet-2088	140	25	agents	agent	NOUN
admet-2088	140	26	to	to	ADP
admet-2088	140	27	tumour	tumour	NOUN
admet-2088	140	28	cells	cell	NOUN
admet-2088	140	29	.	.	PUNCT
admet-2088	141	1	therefore	therefore	ADV
admet-2088	141	2	,	,	PUNCT
admet-2088	141	3	nano	nano	NOUN
admet-2088	141	4	-	-	PUNCT
admet-2088	141	5	delivery	delivery	NOUN
admet-2088	141	6	systems	system	NOUN
admet-2088	141	7	involving	involve	VERB
admet-2088	141	8	nps	nps	PROPN
admet-2088	141	9	,	,	PUNCT
admet-2088	141	10	capable	capable	ADJ
admet-2088	141	11	of	of	ADP
admet-2088	141	12	carrying	carry	VERB
admet-2088	141	13	therapeutic	therapeutic	ADJ
admet-2088	141	14	agents	agent	NOUN
admet-2088	141	15	,	,	PUNCT
admet-2088	141	16	hold	hold	VERB
admet-2088	141	17	great	great	ADJ
admet-2088	141	18	potential	potential	NOUN
admet-2088	141	19	to	to	PART
admet-2088	141	20	improve	improve	VERB
admet-2088	141	21	drug	drug	NOUN
admet-2088	141	22	delivery	delivery	NOUN
admet-2088	141	23	efficiency	efficiency	NOUN
admet-2088	141	24	and	and	CCONJ
admet-2088	141	25	minimise	minimise	NOUN
admet-2088	141	26	side	side	NOUN
admet-2088	141	27	effects	effect	NOUN
admet-2088	141	28	.	.	PUNCT
admet-2088	142	1	these	these	DET
admet-2088	142	2	nano	nano	VERB
admet-2088	142	3	-	-	PUNCT
admet-2088	142	4	dimensional	dimensional	ADJ
admet-2088	142	5	particles	particle	NOUN
admet-2088	142	6	showed	show	VERB
admet-2088	142	7	many	many	ADJ
admet-2088	142	8	advantages	advantage	NOUN
admet-2088	142	9	compared	compare	VERB
admet-2088	142	10	to	to	ADP
admet-2088	142	11	conventional	conventional	ADJ
admet-2088	142	12	drug	drug	NOUN
admet-2088	142	13	delivery	delivery	NOUN
admet-2088	142	14	,	,	PUNCT
admet-2088	142	15	including	include	VERB
admet-2088	142	16	(	(	PUNCT
admet-2088	142	17	i	i	NOUN
admet-2088	142	18	)	)	PUNCT
admet-2088	142	19	improvement	improvement	NOUN
admet-2088	142	20	of	of	ADP
admet-2088	142	21	the	the	DET
admet-2088	142	22	solubility	solubility	NOUN
admet-2088	142	23	of	of	ADP
admet-2088	142	24	poorly	poorly	ADV
admet-2088	142	25	water	water	NOUN
admet-2088	142	26	-	-	PUNCT
admet-2088	142	27	soluble	soluble	ADJ
admet-2088	142	28	drugs	drug	NOUN
admet-2088	142	29	by	by	ADP
admet-2088	142	30	encapsulating	encapsulate	VERB
admet-2088	142	31	them	they	PRON
admet-2088	142	32	,	,	PUNCT
admet-2088	142	33	thereby	thereby	ADV
admet-2088	142	34	increasing	increase	VERB
admet-2088	142	35	the	the	DET
admet-2088	142	36	bioavailability	bioavailability	NOUN
admet-2088	142	37	,	,	PUNCT
admet-2088	142	38	(	(	PUNCT
admet-2088	142	39	ii	ii	NOUN
admet-2088	142	40	)	)	PUNCT
admet-2088	142	41	protection	protection	NOUN
admet-2088	142	42	of	of	ADP
admet-2088	142	43	encapsulated	encapsulate	VERB
admet-2088	142	44	drugs	drug	NOUN
admet-2088	142	45	from	from	ADP
admet-2088	142	46	the	the	DET
admet-2088	142	47	external	external	ADJ
admet-2088	142	48	environment	environment	NOUN
admet-2088	142	49	involving	involve	VERB
admet-2088	142	50	the	the	DET
admet-2088	142	51	presence	presence	NOUN
admet-2088	142	52	of	of	ADP
admet-2088	142	53	enzymes	enzyme	NOUN
admet-2088	142	54	which	which	PRON
admet-2088	142	55	is	be	AUX
admet-2088	142	56	having	have	VERB
admet-2088	142	57	the	the	DET
admet-2088	142	58	potential	potential	NOUN
admet-2088	142	59	to	to	PART
admet-2088	142	60	degrade	degrade	VERB
admet-2088	142	61	them	they	PRON
admet-2088	142	62	,	,	PUNCT
admet-2088	142	63	(	(	PUNCT
admet-2088	142	64	iii	iii	NOUN
admet-2088	142	65	)	)	PUNCT
admet-2088	142	66	surface	surface	NOUN
admet-2088	142	67	modification	modification	NOUN
admet-2088	142	68	through	through	ADP
admet-2088	142	69	pegylation	pegylation	NOUN
admet-2088	142	70	or	or	CCONJ
admet-2088	142	71	conjugation	conjugation	NOUN
admet-2088	142	72	with	with	ADP
admet-2088	142	73	suitable	suitable	ADJ
admet-2088	142	74	ligands	ligand	NOUN
admet-2088	142	75	can	can	AUX
admet-2088	142	76	improve	improve	VERB
admet-2088	142	77	circulation	circulation	NOUN
admet-2088	142	78	time	time	NOUN
admet-2088	142	79	in	in	ADP
admet-2088	142	80	systemic	systemic	ADJ
admet-2088	142	81	circulation	circulation	NOUN
admet-2088	142	82	and	and	CCONJ
admet-2088	142	83	higher	high	ADJ
admet-2088	142	84	accumulation	accumulation	NOUN
admet-2088	142	85	of	of	ADP
admet-2088	142	86	therapeutic	therapeutic	ADJ
admet-2088	142	87	agents	agent	NOUN
admet-2088	142	88	at	at	ADP
admet-2088	142	89	tumour	tumour	NOUN
admet-2088	142	90	sites	site	NOUN
admet-2088	142	91	,	,	PUNCT
admet-2088	142	92	and	and	CCONJ
admet-2088	142	93	(	(	PUNCT
admet-2088	142	94	iv	iv	X
admet-2088	142	95	)	)	PUNCT
admet-2088	142	96	allow	allow	VERB
admet-2088	142	97	the	the	DET
admet-2088	142	98	incorporation	incorporation	NOUN
admet-2088	142	99	of	of	ADP
admet-2088	142	100	more	more	ADJ
admet-2088	142	101	than	than	ADP
admet-2088	142	102	one	one	NUM
admet-2088	142	103	drugs	drug	NOUN
admet-2088	142	104	or	or	CCONJ
admet-2088	142	105	encapsulation	encapsulation	NOUN
admet-2088	142	106	of	of	ADP
admet-2088	142	107	more	more	ADJ
admet-2088	142	108	than	than	ADP
admet-2088	142	109	one	one	NUM
admet-2088	142	110	agent	agent	NOUN
admet-2088	142	111	for	for	ADP
admet-2088	142	112	combination	combination	NOUN
admet-2088	142	113	therapy	therapy	NOUN
admet-2088	142	114	and	and	CCONJ
admet-2088	142	115	derive	derive	VERB
admet-2088	142	116	synergistic	synergistic	ADJ
admet-2088	142	117	effect	effect	NOUN
admet-2088	142	118	for	for	ADP
admet-2088	142	119	better	well	ADJ
admet-2088	142	120	treatment	treatment	NOUN
admet-2088	142	121	of	of	ADP
admet-2088	142	122	melanoma	melanoma	NOUN
admet-2088	142	123	[	[	X
admet-2088	142	124	40	40	NUM
admet-2088	142	125	]	]	PUNCT
admet-2088	142	126	.	.	PUNCT
admet-2088	143	1	delivery	delivery	NOUN
admet-2088	143	2	routes	route	NOUN
admet-2088	143	3	for	for	ADP
admet-2088	143	4	therapeutic	therapeutic	ADJ
admet-2088	143	5	agents	agent	NOUN
admet-2088	143	6	after	after	ADP
admet-2088	143	7	various	various	ADJ
admet-2088	143	8	treatment	treatment	NOUN
admet-2088	143	9	options	option	NOUN
admet-2088	143	10	for	for	ADP
admet-2088	143	11	melanoma	melanoma	NOUN
admet-2088	143	12	,	,	PUNCT
admet-2088	143	13	the	the	DET
admet-2088	143	14	next	next	ADJ
admet-2088	143	15	answer	answer	NOUN
admet-2088	143	16	to	to	PART
admet-2088	143	17	find	find	VERB
admet-2088	143	18	out	out	ADP
admet-2088	143	19	is	be	AUX
admet-2088	143	20	their	their	PRON
admet-2088	143	21	routes	route	NOUN
admet-2088	143	22	of	of	ADP
admet-2088	143	23	delivery	delivery	NOUN
admet-2088	143	24	.	.	PUNCT
admet-2088	144	1	basically	basically	ADV
admet-2088	144	2	,	,	PUNCT
admet-2088	144	3	there	there	PRON
admet-2088	144	4	are	be	VERB
admet-2088	144	5	three	three	NUM
admet-2088	144	6	routes	route	NOUN
admet-2088	144	7	of	of	ADP
admet-2088	144	8	delivery	delivery	NOUN
admet-2088	144	9	:	:	PUNCT
admet-2088	144	10	topical	topical	ADJ
admet-2088	144	11	,	,	PUNCT
admet-2088	144	12	transdermal	transdermal	ADJ
admet-2088	144	13	and	and	CCONJ
admet-2088	144	14	parenteral	parenteral	ADJ
admet-2088	144	15	routes	route	NOUN
admet-2088	144	16	.	.	PUNCT
admet-2088	145	1	in	in	ADP
admet-2088	145	2	most	most	ADJ
admet-2088	145	3	skin	skin	NOUN
admet-2088	145	4	cancer	cancer	NOUN
admet-2088	145	5	cases	case	NOUN
admet-2088	145	6	,	,	PUNCT
admet-2088	145	7	topical	topical	ADJ
admet-2088	145	8	delivery	delivery	NOUN
admet-2088	145	9	of	of	ADP
admet-2088	145	10	therapeutics	therapeutic	NOUN
admet-2088	145	11	is	be	AUX
admet-2088	145	12	preferred	prefer	VERB
admet-2088	145	13	because	because	SCONJ
admet-2088	145	14	they	they	PRON
admet-2088	145	15	avoid	avoid	VERB
admet-2088	145	16	the	the	DET
admet-2088	145	17	potential	potential	ADJ
admet-2088	145	18	toxic	toxic	ADJ
admet-2088	145	19	effects	effect	NOUN
admet-2088	145	20	of	of	ADP
admet-2088	145	21	systemic	systemic	ADJ
admet-2088	145	22	agents	agent	NOUN
admet-2088	145	23	.	.	PUNCT
admet-2088	146	1	it	it	PRON
admet-2088	146	2	is	be	AUX
admet-2088	146	3	highly	highly	ADV
admet-2088	146	4	desirable	desirable	ADJ
admet-2088	146	5	in	in	ADP
admet-2088	146	6	pre	pre	ADJ
admet-2088	146	7	-	-	ADJ
admet-2088	146	8	cancerous	cancerous	ADJ
admet-2088	146	9	lesions	lesion	NOUN
admet-2088	146	10	or	or	CCONJ
admet-2088	146	11	in	in	ADP
admet-2088	146	12	-	-	PUNCT
admet-2088	146	13	transit	transit	NOUN
admet-2088	146	14	disease	disease	NOUN
admet-2088	146	15	[	[	X
admet-2088	146	16	62	62	NUM
admet-2088	146	17	]	]	PUNCT
admet-2088	146	18	.	.	PUNCT
admet-2088	147	1	however	however	ADV
admet-2088	147	2	,	,	PUNCT
admet-2088	147	3	the	the	DET
admet-2088	147	4	topical	topical	ADJ
admet-2088	147	5	route	route	NOUN
admet-2088	147	6	suffers	suffer	VERB
admet-2088	147	7	due	due	ADP
admet-2088	147	8	to	to	ADP
admet-2088	147	9	the	the	DET
admet-2088	147	10	risk	risk	NOUN
admet-2088	147	11	of	of	ADP
admet-2088	147	12	metastasis	metastasis	NOUN
admet-2088	147	13	and	and	CCONJ
admet-2088	147	14	presently	presently	ADV
admet-2088	147	15	,	,	PUNCT
admet-2088	147	16	there	there	PRON
admet-2088	147	17	is	be	VERB
admet-2088	147	18	no	no	DET
admet-2088	147	19	fda	fda	PROPN
admet-2088	147	20	-	-	PUNCT
admet-2088	147	21	approved	approve	VERB
admet-2088	147	22	topical	topical	ADJ
admet-2088	147	23	therapy	therapy	NOUN
admet-2088	147	24	for	for	ADP
admet-2088	147	25	melanoma	melanoma	NOUN
admet-2088	147	26	.	.	PUNCT
admet-2088	148	1	in	in	ADP
admet-2088	148	2	addition	addition	NOUN
admet-2088	148	3	,	,	PUNCT
admet-2088	148	4	the	the	DET
admet-2088	148	5	barrier	barrier	NOUN
admet-2088	148	6	nature	nature	NOUN
admet-2088	148	7	of	of	ADP
admet-2088	148	8	the	the	DET
admet-2088	148	9	stratum	stratum	NOUN
admet-2088	148	10	corneum	corneum	NOUN
admet-2088	148	11	of	of	ADP
admet-2088	148	12	the	the	DET
admet-2088	148	13	epidermis	epidermis	NOUN
admet-2088	148	14	prevents	prevent	VERB
admet-2088	148	15	the	the	DET
admet-2088	148	16	entry	entry	NOUN
admet-2088	148	17	of	of	ADP
admet-2088	148	18	therapeutic	therapeutic	ADJ
admet-2088	148	19	agents	agent	NOUN
admet-2088	148	20	into	into	ADP
admet-2088	148	21	deeper	deep	ADJ
admet-2088	148	22	skin	skin	NOUN
admet-2088	148	23	layers	layer	NOUN
admet-2088	148	24	.	.	PUNCT
admet-2088	149	1	in	in	ADP
admet-2088	149	2	this	this	DET
admet-2088	149	3	context	context	NOUN
admet-2088	149	4	,	,	PUNCT
admet-2088	149	5	the	the	DET
admet-2088	149	6	transdermal	transdermal	ADJ
admet-2088	149	7	route	route	NOUN
admet-2088	149	8	using	use	VERB
admet-2088	149	9	chemical	chemical	NOUN
admet-2088	149	10	and	and	CCONJ
admet-2088	149	11	various	various	ADJ
admet-2088	149	12	physical	physical	ADJ
admet-2088	149	13	techniques	technique	NOUN
admet-2088	149	14	remains	remain	VERB
admet-2088	149	15	a	a	DET
admet-2088	149	16	highly	highly	ADV
admet-2088	149	17	efficient	efficient	ADJ
admet-2088	149	18	route	route	NOUN
admet-2088	149	19	of	of	ADP
admet-2088	149	20	choice	choice	NOUN
admet-2088	149	21	in	in	ADP
admet-2088	149	22	melanoma	melanoma	ADJ
admet-2088	149	23	treatment	treatment	NOUN
admet-2088	149	24	.	.	PUNCT
admet-2088	150	1	the	the	DET
admet-2088	150	2	barrier	barrier	NOUN
admet-2088	150	3	nature	nature	NOUN
admet-2088	150	4	of	of	ADP
admet-2088	150	5	stratum	stratum	NOUN
admet-2088	150	6	corneum	corneum	NOUN
admet-2088	150	7	can	can	AUX
admet-2088	150	8	be	be	AUX
admet-2088	150	9	reversibly	reversibly	ADV
admet-2088	150	10	altered	alter	VERB
admet-2088	150	11	with	with	ADP
admet-2088	150	12	chemical	chemical	ADJ
admet-2088	150	13	penetration	penetration	NOUN
admet-2088	150	14	enhancers	enhancer	NOUN
admet-2088	150	15	and	and	CCONJ
admet-2088	150	16	allow	allow	VERB
admet-2088	150	17	the	the	DET
admet-2088	150	18	penetration	penetration	NOUN
admet-2088	150	19	of	of	ADP
admet-2088	150	20	considerably	considerably	ADV
admet-2088	150	21	larger	large	ADJ
admet-2088	150	22	particles	particle	NOUN
admet-2088	150	23	compared	compare	VERB
admet-2088	150	24	to	to	ADP
admet-2088	150	25	the	the	DET
admet-2088	150	26	topical	topical	ADJ
admet-2088	150	27	route	route	NOUN
admet-2088	150	28	.	.	PUNCT
admet-2088	151	1	np	np	INTJ
admet-2088	151	2	strategy	strategy	NOUN
admet-2088	151	3	employing	employ	VERB
admet-2088	151	4	polymeric	polymeric	ADJ
admet-2088	151	5	nps	nps	PROPN
admet-2088	151	6	,	,	PUNCT
admet-2088	151	7	liposomes	liposome	NOUN
admet-2088	151	8	,	,	PUNCT
admet-2088	151	9	admet	admet	PROPN
admet-2088	151	10	&	&	CCONJ
admet-2088	151	11	dmpk	dmpk	PROPN
admet-2088	151	12	12(1	12(1	PROPN
admet-2088	151	13	)	)	PUNCT
admet-2088	151	14	(	(	PUNCT
admet-2088	151	15	2024	2024	NUM
admet-2088	151	16	)	)	PUNCT
admet-2088	151	17	107	107	NUM
admet-2088	151	18	-	-	SYM
admet-2088	151	19	150	150	NUM
admet-2088	151	20	nanomaterial	nanomaterial	NOUN
admet-2088	151	21	-	-	PUNCT
admet-2088	151	22	based	base	VERB
admet-2088	151	23	drug	drug	NOUN
admet-2088	151	24	delivery	delivery	NOUN
admet-2088	151	25	systems	system	NOUN
admet-2088	151	26	for	for	ADP
admet-2088	151	27	melanoma	melanoma	NOUN
admet-2088	151	28	therapy	therapy	NOUN
admet-2088	151	29	doi	doi	NOUN
admet-2088	151	30	:	:	PUNCT
admet-2088	151	31	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	151	32	113	113	NUM
admet-2088	151	33	niosomes	niosome	NOUN
admet-2088	151	34	,	,	PUNCT
admet-2088	151	35	transferosomes	transferosome	NOUN
admet-2088	151	36	,	,	PUNCT
admet-2088	151	37	etc	etc	X
admet-2088	151	38	.	.	X
admet-2088	151	39	,	,	PUNCT
admet-2088	151	40	can	can	AUX
admet-2088	151	41	be	be	AUX
admet-2088	151	42	seen	see	VERB
admet-2088	151	43	as	as	ADP
admet-2088	151	44	an	an	DET
admet-2088	151	45	alternative	alternative	ADJ
admet-2088	151	46	way	way	NOUN
admet-2088	151	47	to	to	PART
admet-2088	151	48	enhance	enhance	VERB
admet-2088	151	49	the	the	DET
admet-2088	151	50	penetration	penetration	NOUN
admet-2088	151	51	of	of	ADP
admet-2088	151	52	therapeutics	therapeutic	NOUN
admet-2088	151	53	across	across	ADP
admet-2088	151	54	the	the	DET
admet-2088	151	55	epidermis	epidermis	NOUN
admet-2088	152	1	[	[	X
admet-2088	152	2	43	43	NUM
admet-2088	152	3	]	]	PUNCT
admet-2088	152	4	.	.	PUNCT
admet-2088	153	1	if	if	SCONJ
admet-2088	153	2	further	further	ADJ
admet-2088	153	3	enhancement	enhancement	NOUN
admet-2088	153	4	of	of	ADP
admet-2088	153	5	penetration	penetration	NOUN
admet-2088	153	6	of	of	ADP
admet-2088	153	7	therapeutics	therapeutic	NOUN
admet-2088	153	8	is	be	AUX
admet-2088	153	9	desired	desire	VERB
admet-2088	153	10	,	,	PUNCT
admet-2088	153	11	then	then	ADV
admet-2088	153	12	the	the	DET
admet-2088	153	13	combination	combination	NOUN
admet-2088	153	14	of	of	ADP
admet-2088	153	15	microneedle	microneedle	NOUN
admet-2088	153	16	(	(	PUNCT
admet-2088	153	17	mns)-based	mns)-base	VERB
admet-2088	153	18	minimally	minimally	ADV
admet-2088	153	19	-	-	PUNCT
admet-2088	153	20	invasive	invasive	ADJ
admet-2088	153	21	physical	physical	ADJ
admet-2088	153	22	techniques	technique	NOUN
admet-2088	153	23	can	can	AUX
admet-2088	153	24	be	be	AUX
admet-2088	153	25	employed	employ	VERB
admet-2088	153	26	alone	alone	ADJ
admet-2088	153	27	or	or	CCONJ
admet-2088	153	28	in	in	ADP
admet-2088	153	29	combination	combination	NOUN
admet-2088	153	30	with	with	ADP
admet-2088	153	31	nms	nms	PROPN
admet-2088	153	32	.	.	PUNCT
admet-2088	154	1	mn	mn	PROPN
admet-2088	154	2	technique	technique	NOUN
admet-2088	154	3	comprised	comprise	VERB
admet-2088	154	4	of	of	ADP
admet-2088	154	5	a	a	DET
admet-2088	154	6	number	number	NOUN
admet-2088	154	7	of	of	ADP
admet-2088	154	8	micron	micron	NOUN
admet-2088	154	9	-	-	PUNCT
admet-2088	154	10	sized	sized	ADJ
admet-2088	154	11	needles	needle	NOUN
admet-2088	154	12	upon	upon	SCONJ
admet-2088	154	13	their	their	PRON
admet-2088	154	14	application	application	NOUN
admet-2088	154	15	on	on	ADP
admet-2088	154	16	the	the	DET
admet-2088	154	17	skin	skin	NOUN
admet-2088	154	18	surface	surface	NOUN
admet-2088	154	19	can	can	AUX
admet-2088	154	20	penetrate	penetrate	VERB
admet-2088	154	21	the	the	DET
admet-2088	154	22	stratum	stratum	NOUN
admet-2088	154	23	corneum	corneum	NOUN
admet-2088	154	24	and	and	CCONJ
admet-2088	154	25	thus	thus	ADV
admet-2088	154	26	create	create	VERB
admet-2088	154	27	micro	micro	NOUN
admet-2088	154	28	-	-	NOUN
admet-2088	154	29	conduits	conduit	NOUN
admet-2088	154	30	in	in	ADP
admet-2088	154	31	the	the	DET
admet-2088	154	32	skin	skin	NOUN
admet-2088	154	33	through	through	ADP
admet-2088	154	34	which	which	PRON
admet-2088	154	35	therapeutic	therapeutic	ADJ
admet-2088	154	36	molecules	molecule	NOUN
admet-2088	154	37	or	or	CCONJ
admet-2088	154	38	nms	nms	NOUN
admet-2088	154	39	can	can	AUX
admet-2088	154	40	pass	pass	VERB
admet-2088	154	41	and	and	CCONJ
admet-2088	154	42	reach	reach	VERB
admet-2088	154	43	viable	viable	ADJ
admet-2088	154	44	epidermis	epidermis	NOUN
admet-2088	155	1	[	[	X
admet-2088	155	2	63	63	NUM
admet-2088	155	3	]	]	PUNCT
admet-2088	155	4	.	.	PUNCT
admet-2088	156	1	due	due	ADP
admet-2088	156	2	to	to	ADP
admet-2088	156	3	recent	recent	ADJ
admet-2088	156	4	success	success	NOUN
admet-2088	156	5	,	,	PUNCT
admet-2088	156	6	mn	mn	PROPN
admet-2088	156	7	techniques	technique	NOUN
admet-2088	156	8	are	be	AUX
admet-2088	156	9	combined	combine	VERB
admet-2088	156	10	with	with	ADP
admet-2088	156	11	other	other	ADJ
admet-2088	156	12	therapies	therapy	NOUN
admet-2088	156	13	such	such	ADJ
admet-2088	156	14	as	as	ADP
admet-2088	156	15	pdt	pdt	PROPN
admet-2088	156	16	,	,	PUNCT
admet-2088	156	17	ptt	ptt	NOUN
admet-2088	156	18	,	,	PUNCT
admet-2088	156	19	chemotherapy	chemotherapy	NOUN
admet-2088	156	20	,	,	PUNCT
admet-2088	156	21	and	and	CCONJ
admet-2088	156	22	immunotherapy	immunotherapy	NOUN
admet-2088	156	23	for	for	ADP
admet-2088	156	24	synergistic	synergistic	ADJ
admet-2088	156	25	effects	effect	NOUN
admet-2088	156	26	against	against	ADP
admet-2088	156	27	melanoma	melanoma	NOUN
admet-2088	156	28	[	[	X
admet-2088	156	29	64	64	NUM
admet-2088	156	30	]	]	PUNCT
admet-2088	156	31	.	.	PUNCT
admet-2088	157	1	the	the	DET
admet-2088	157	2	main	main	ADJ
admet-2088	157	3	advantage	advantage	NOUN
admet-2088	157	4	of	of	ADP
admet-2088	157	5	the	the	DET
admet-2088	157	6	transdermal	transdermal	ADJ
admet-2088	157	7	route	route	NOUN
admet-2088	157	8	is	be	AUX
admet-2088	157	9	the	the	DET
admet-2088	157	10	local	local	ADJ
admet-2088	157	11	delivery	delivery	NOUN
admet-2088	157	12	of	of	ADP
admet-2088	157	13	therapeutic	therapeutic	ADJ
admet-2088	157	14	agents	agent	NOUN
admet-2088	157	15	and	and	CCONJ
admet-2088	157	16	,	,	PUNCT
admet-2088	157	17	thereby	thereby	ADV
admet-2088	157	18	,	,	PUNCT
admet-2088	157	19	avoidance	avoidance	NOUN
admet-2088	157	20	of	of	ADP
admet-2088	157	21	systemic	systemic	ADJ
admet-2088	157	22	toxicity	toxicity	NOUN
admet-2088	157	23	.	.	PUNCT
admet-2088	158	1	the	the	DET
admet-2088	158	2	parenteral	parenteral	ADJ
admet-2088	158	3	route	route	NOUN
admet-2088	158	4	is	be	AUX
admet-2088	158	5	opted	opt	VERB
admet-2088	158	6	for	for	ADP
admet-2088	158	7	only	only	ADV
admet-2088	158	8	advanced	advanced	ADJ
admet-2088	158	9	metastatic	metastatic	ADJ
admet-2088	158	10	melanoma	melanoma	NOUN
admet-2088	158	11	,	,	PUNCT
admet-2088	158	12	where	where	SCONJ
admet-2088	158	13	other	other	ADJ
admet-2088	158	14	routes	route	NOUN
admet-2088	158	15	are	be	AUX
admet-2088	158	16	ineffective	ineffective	ADJ
admet-2088	158	17	.	.	PUNCT
admet-2088	159	1	the	the	DET
admet-2088	159	2	therapeutic	therapeutic	ADJ
admet-2088	159	3	agents	agent	NOUN
admet-2088	159	4	administered	administer	VERB
admet-2088	159	5	through	through	ADP
admet-2088	159	6	the	the	DET
admet-2088	159	7	parenteral	parenteral	ADJ
admet-2088	159	8	route	route	NOUN
admet-2088	159	9	include	include	VERB
admet-2088	159	10	immunotherapeutic	immunotherapeutic	ADJ
admet-2088	159	11	agents	agent	NOUN
admet-2088	159	12	,	,	PUNCT
admet-2088	159	13	chemotherapeutic	chemotherapeutic	ADJ
admet-2088	159	14	agents	agent	NOUN
admet-2088	159	15	and	and	CCONJ
admet-2088	159	16	the	the	DET
admet-2088	159	17	inhibitors	inhibitor	NOUN
admet-2088	159	18	used	use	VERB
admet-2088	159	19	in	in	ADP
admet-2088	159	20	targeted	target	VERB
admet-2088	159	21	therapy	therapy	NOUN
admet-2088	159	22	[	[	X
admet-2088	159	23	65	65	NUM
admet-2088	159	24	]	]	PUNCT
admet-2088	159	25	.	.	PUNCT
admet-2088	160	1	however	however	ADV
admet-2088	160	2	,	,	PUNCT
admet-2088	160	3	the	the	DET
admet-2088	160	4	parenteral	parenteral	ADJ
admet-2088	160	5	route	route	NOUN
admet-2088	160	6	is	be	AUX
admet-2088	160	7	limited	limit	VERB
admet-2088	160	8	by	by	ADP
admet-2088	160	9	the	the	DET
admet-2088	160	10	non	non	ADJ
admet-2088	160	11	-	-	ADJ
admet-2088	160	12	specific	specific	ADJ
admet-2088	160	13	delivery	delivery	NOUN
admet-2088	160	14	of	of	ADP
admet-2088	160	15	therapeutic	therapeutic	ADJ
admet-2088	160	16	agents	agent	NOUN
admet-2088	160	17	,	,	PUNCT
admet-2088	160	18	leading	lead	VERB
admet-2088	160	19	to	to	ADP
admet-2088	160	20	a	a	DET
admet-2088	160	21	reduction	reduction	NOUN
admet-2088	160	22	in	in	ADP
admet-2088	160	23	efficacy	efficacy	NOUN
admet-2088	160	24	,	,	PUNCT
admet-2088	160	25	cutaneous	cutaneous	ADJ
admet-2088	160	26	and	and	CCONJ
admet-2088	160	27	extracutaneous	extracutaneous	ADJ
admet-2088	160	28	adverse	adverse	ADJ
admet-2088	160	29	effects	effect	NOUN
admet-2088	160	30	shown	show	VERB
admet-2088	160	31	by	by	ADP
admet-2088	160	32	many	many	ADJ
admet-2088	160	33	therapeutic	therapeutic	ADJ
admet-2088	160	34	agents	agent	NOUN
admet-2088	160	35	and	and	CCONJ
admet-2088	160	36	minimum	minimum	ADJ
admet-2088	160	37	uptake	uptake	NOUN
admet-2088	160	38	of	of	ADP
admet-2088	160	39	therapeutic	therapeutic	ADJ
admet-2088	160	40	agents	agent	NOUN
admet-2088	160	41	in	in	ADP
admet-2088	160	42	melanocytes	melanocyte	NOUN
admet-2088	160	43	[	[	X
admet-2088	160	44	66	66	NUM
admet-2088	160	45	]	]	PUNCT
admet-2088	160	46	.	.	PUNCT
admet-2088	161	1	classification	classification	NOUN
admet-2088	161	2	of	of	ADP
admet-2088	161	3	nanomaterials	nanomaterial	NOUN
admet-2088	161	4	nms	nms	NOUN
admet-2088	161	5	can	can	AUX
admet-2088	161	6	be	be	AUX
admet-2088	161	7	classified	classify	VERB
admet-2088	161	8	into	into	ADP
admet-2088	161	9	various	various	ADJ
admet-2088	161	10	groups	group	NOUN
admet-2088	161	11	based	base	VERB
admet-2088	161	12	on	on	ADP
admet-2088	161	13	different	different	ADJ
admet-2088	161	14	criteria	criterion	NOUN
admet-2088	161	15	such	such	ADJ
admet-2088	161	16	as	as	ADP
admet-2088	161	17	chemical	chemical	ADJ
admet-2088	161	18	nature	nature	NOUN
admet-2088	161	19	,	,	PUNCT
admet-2088	161	20	dimensions	dimension	NOUN
admet-2088	161	21	,	,	PUNCT
admet-2088	161	22	state	state	NOUN
admet-2088	161	23	and	and	CCONJ
admet-2088	161	24	morphology	morphology	NOUN
admet-2088	161	25	.	.	PUNCT
admet-2088	162	1	however	however	ADV
admet-2088	162	2	,	,	PUNCT
admet-2088	162	3	nms	nms	PROPN
admet-2088	162	4	employed	employ	VERB
admet-2088	162	5	in	in	ADP
admet-2088	162	6	drug	drug	NOUN
admet-2088	162	7	delivery	delivery	NOUN
admet-2088	162	8	applications	application	NOUN
admet-2088	162	9	are	be	AUX
admet-2088	162	10	broadly	broadly	ADV
admet-2088	162	11	classified	classify	VERB
admet-2088	162	12	into	into	ADP
admet-2088	162	13	two	two	NUM
admet-2088	162	14	categories	category	NOUN
admet-2088	162	15	:	:	PUNCT
admet-2088	162	16	inorganic	inorganic	NOUN
admet-2088	162	17	and	and	CCONJ
admet-2088	162	18	organic	organic	ADJ
admet-2088	162	19	nms	nms	NOUN
admet-2088	162	20	.	.	PUNCT
admet-2088	163	1	based	base	VERB
admet-2088	163	2	on	on	ADP
admet-2088	163	3	their	their	PRON
admet-2088	163	4	chemical	chemical	NOUN
admet-2088	163	5	nature	nature	NOUN
admet-2088	163	6	,	,	PUNCT
admet-2088	163	7	they	they	PRON
admet-2088	163	8	are	be	AUX
admet-2088	163	9	classified	classify	VERB
admet-2088	163	10	into	into	ADP
admet-2088	163	11	inorganic	inorganic	ADJ
admet-2088	163	12	,	,	PUNCT
admet-2088	163	13	organic	organic	ADJ
admet-2088	163	14	and	and	CCONJ
admet-2088	163	15	cell	cell	NOUN
admet-2088	163	16	-	-	PUNCT
admet-2088	163	17	derived	derive	VERB
admet-2088	163	18	/	/	SYM
admet-2088	163	19	extracellular	extracellular	ADJ
admet-2088	163	20	vesicles	vesicle	NOUN
admet-2088	163	21	figure	figure	VERB
admet-2088	163	22	2	2	NUM
admet-2088	164	1	[	[	SYM
admet-2088	164	2	67	67	NUM
admet-2088	164	3	-	-	SYM
admet-2088	164	4	69	69	NUM
admet-2088	164	5	]	]	PUNCT
admet-2088	164	6	.	.	PUNCT
admet-2088	165	1	figure	figure	NOUN
admet-2088	165	2	2	2	NUM
admet-2088	165	3	.	.	PUNCT
admet-2088	165	4	schematic	schematic	ADJ
admet-2088	165	5	representation	representation	NOUN
admet-2088	165	6	of	of	ADP
admet-2088	165	7	classification	classification	NOUN
admet-2088	165	8	of	of	ADP
admet-2088	165	9	nanomaterials	nanomaterial	NOUN
admet-2088	165	10	employed	employ	VERB
admet-2088	165	11	in	in	ADP
admet-2088	165	12	the	the	DET
admet-2088	165	13	treatment	treatment	NOUN
admet-2088	165	14	of	of	ADP
admet-2088	165	15	melanoma	melanoma	NOUN
admet-2088	165	16	.	.	PUNCT
admet-2088	166	1	inorganic	inorganic	ADJ
admet-2088	166	2	nanomaterials	nanomaterial	NOUN
admet-2088	166	3	inorganic	inorganic	PROPN
admet-2088	166	4	nms	nms	NOUN
admet-2088	166	5	have	have	AUX
admet-2088	166	6	been	be	AUX
admet-2088	166	7	extensively	extensively	ADV
admet-2088	166	8	explored	explore	VERB
admet-2088	166	9	for	for	ADP
admet-2088	166	10	decades	decade	NOUN
admet-2088	166	11	for	for	ADP
admet-2088	166	12	applications	application	NOUN
admet-2088	166	13	in	in	ADP
admet-2088	166	14	diverse	diverse	ADJ
admet-2088	166	15	fields	field	NOUN
admet-2088	166	16	,	,	PUNCT
admet-2088	166	17	including	include	VERB
admet-2088	166	18	diagnostic	diagnostic	ADJ
admet-2088	166	19	and	and	CCONJ
admet-2088	166	20	therapeutic	therapeutic	ADJ
admet-2088	166	21	applications	application	NOUN
admet-2088	166	22	.	.	PUNCT
admet-2088	167	1	this	this	PRON
admet-2088	167	2	is	be	AUX
admet-2088	167	3	mostly	mostly	ADV
admet-2088	167	4	due	due	ADJ
admet-2088	167	5	to	to	ADP
admet-2088	167	6	their	their	PRON
admet-2088	167	7	uniform	uniform	ADJ
admet-2088	167	8	sizes	size	NOUN
admet-2088	167	9	with	with	ADP
admet-2088	167	10	high	high	ADJ
admet-2088	167	11	dispersion	dispersion	NOUN
admet-2088	167	12	.	.	PUNCT
admet-2088	168	1	in	in	ADP
admet-2088	168	2	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	168	3	m.	m.	NOUN
admet-2088	168	4	kulkarni	kulkarni	PROPN
admet-2088	168	5	et	et	PROPN
admet-2088	168	6	al	al	PROPN
admet-2088	168	7	.	.	PROPN
admet-2088	168	8	admet	admet	PROPN
admet-2088	168	9	&	&	CCONJ
admet-2088	168	10	dmpk	dmpk	PROPN
admet-2088	168	11	12(1	12(1	PROPN
admet-2088	168	12	)	)	PUNCT
admet-2088	168	13	(	(	PUNCT
admet-2088	168	14	2024	2024	NUM
admet-2088	168	15	)	)	PUNCT
admet-2088	168	16	107	107	NUM
admet-2088	168	17	-	-	SYM
admet-2088	168	18	150	150	NUM
admet-2088	168	19	114	114	NUM
admet-2088	168	20	addition	addition	NOUN
admet-2088	168	21	,	,	PUNCT
admet-2088	168	22	inorganic	inorganic	ADJ
admet-2088	168	23	nms	nms	NOUN
admet-2088	168	24	are	be	AUX
admet-2088	168	25	comparatively	comparatively	ADV
admet-2088	168	26	facile	facile	ADJ
admet-2088	168	27	to	to	PART
admet-2088	168	28	construct	construct	VERB
admet-2088	168	29	and	and	CCONJ
admet-2088	168	30	provide	provide	VERB
admet-2088	168	31	high	high	ADJ
admet-2088	168	32	yield	yield	NOUN
admet-2088	168	33	[	[	X
admet-2088	168	34	70	70	NUM
admet-2088	168	35	]	]	PUNCT
admet-2088	168	36	.	.	PUNCT
admet-2088	169	1	these	these	DET
admet-2088	169	2	nms	nms	PROPN
admet-2088	169	3	allows	allow	VERB
admet-2088	169	4	various	various	ADJ
admet-2088	169	5	chemical	chemical	ADJ
admet-2088	169	6	modulation	modulation	NOUN
admet-2088	169	7	on	on	ADP
admet-2088	169	8	their	their	PRON
admet-2088	169	9	surface	surface	NOUN
admet-2088	169	10	,	,	PUNCT
admet-2088	169	11	such	such	ADJ
admet-2088	169	12	as	as	ADP
admet-2088	169	13	ligand	ligand	NOUN
admet-2088	169	14	conjugation	conjugation	NOUN
admet-2088	169	15	,	,	PUNCT
admet-2088	169	16	charge	charge	NOUN
admet-2088	169	17	modulation	modulation	NOUN
admet-2088	169	18	,	,	PUNCT
admet-2088	169	19	polyethylene	polyethylene	NOUN
admet-2088	169	20	glycol	glycol	NOUN
admet-2088	169	21	conjugation	conjugation	NOUN
admet-2088	169	22	(	(	PUNCT
admet-2088	169	23	pegylation	pegylation	NOUN
admet-2088	169	24	)	)	PUNCT
admet-2088	169	25	,	,	PUNCT
admet-2088	169	26	and	and	CCONJ
admet-2088	169	27	the	the	DET
admet-2088	169	28	inclusion	inclusion	NOUN
admet-2088	169	29	of	of	ADP
admet-2088	169	30	small	small	ADJ
admet-2088	169	31	-	-	PUNCT
admet-2088	169	32	molecule	molecule	NOUN
admet-2088	169	33	probes	probe	NOUN
admet-2088	169	34	and	and	CCONJ
admet-2088	169	35	stimuli	stimulus	NOUN
admet-2088	169	36	-	-	PUNCT
admet-2088	169	37	responsive	responsive	ADJ
admet-2088	169	38	moieties	moiety	NOUN
admet-2088	169	39	for	for	ADP
admet-2088	169	40	the	the	DET
admet-2088	169	41	improvement	improvement	NOUN
admet-2088	169	42	of	of	ADP
admet-2088	169	43	drug	drug	NOUN
admet-2088	169	44	efficiency	efficiency	NOUN
admet-2088	169	45	[	[	X
admet-2088	169	46	71,72	71,72	NOUN
admet-2088	169	47	]	]	PUNCT
admet-2088	169	48	.	.	PUNCT
admet-2088	170	1	further	far	ADV
admet-2088	170	2	,	,	PUNCT
admet-2088	170	3	appropriate	appropriate	ADJ
admet-2088	170	4	modification	modification	NOUN
admet-2088	170	5	may	may	AUX
admet-2088	170	6	lead	lead	VERB
admet-2088	170	7	to	to	ADP
admet-2088	170	8	the	the	DET
admet-2088	170	9	enhancement	enhancement	NOUN
admet-2088	170	10	of	of	ADP
admet-2088	170	11	their	their	PRON
admet-2088	170	12	water	water	NOUN
admet-2088	170	13	solubility	solubility	NOUN
admet-2088	170	14	and	and	CCONJ
admet-2088	170	15	,	,	PUNCT
admet-2088	170	16	subsequently	subsequently	ADV
admet-2088	170	17	,	,	PUNCT
admet-2088	170	18	bioavailability	bioavailability	NOUN
admet-2088	170	19	.	.	PUNCT
admet-2088	171	1	moreover	moreover	ADV
admet-2088	171	2	,	,	PUNCT
admet-2088	171	3	drug	drug	NOUN
admet-2088	171	4	molecules	molecule	NOUN
admet-2088	171	5	can	can	AUX
admet-2088	171	6	be	be	AUX
admet-2088	171	7	conjugated	conjugate	VERB
admet-2088	171	8	with	with	ADP
admet-2088	171	9	inorganic	inorganic	ADJ
admet-2088	171	10	nms	nms	NOUN
admet-2088	171	11	,	,	PUNCT
admet-2088	171	12	facilitating	facilitate	VERB
admet-2088	171	13	drug	drug	NOUN
admet-2088	171	14	delivery	delivery	NOUN
admet-2088	171	15	applications	application	NOUN
admet-2088	171	16	.	.	PUNCT
admet-2088	172	1	inorganic	inorganic	PROPN
admet-2088	172	2	nms	nms	PROPN
admet-2088	172	3	are	be	AUX
admet-2088	172	4	broadly	broadly	ADV
admet-2088	172	5	classified	classify	VERB
admet-2088	172	6	into	into	ADP
admet-2088	172	7	metallic	metallic	ADJ
admet-2088	172	8	nms	nms	NOUN
admet-2088	172	9	and	and	CCONJ
admet-2088	172	10	carbon	carbon	NOUN
admet-2088	172	11	-	-	PUNCT
admet-2088	172	12	based	base	VERB
admet-2088	172	13	nms	nms	NOUN
admet-2088	172	14	(	(	PUNCT
admet-2088	172	15	figure	figure	NOUN
admet-2088	172	16	3	3	NUM
admet-2088	172	17	)	)	PUNCT
admet-2088	172	18	.	.	PUNCT
admet-2088	173	1	figure	figure	VERB
admet-2088	173	2	3	3	NUM
admet-2088	173	3	.	.	PUNCT
admet-2088	173	4	illustration	illustration	NOUN
admet-2088	173	5	of	of	ADP
admet-2088	173	6	types	type	NOUN
admet-2088	173	7	of	of	ADP
admet-2088	173	8	inorganic	inorganic	ADJ
admet-2088	173	9	nms	nms	NOUN
admet-2088	173	10	:	:	PUNCT
admet-2088	173	11	metal	metal	NOUN
admet-2088	173	12	-	-	PUNCT
admet-2088	173	13	based	base	VERB
admet-2088	173	14	nms	nms	NOUN
admet-2088	173	15	and	and	CCONJ
admet-2088	173	16	carbon	carbon	NOUN
admet-2088	173	17	-	-	PUNCT
admet-2088	173	18	based	base	VERB
admet-2088	173	19	nms	nms	NOUN
admet-2088	173	20	.	.	PUNCT
admet-2088	174	1	nps	nps	PROPN
admet-2088	174	2	:	:	PUNCT
admet-2088	174	3	nanoparticles	nanoparticle	NOUN
admet-2088	174	4	,	,	PUNCT
admet-2088	174	5	ctnps	ctnps	NOUN
admet-2088	174	6	:	:	PUNCT
admet-2088	174	7	copper	copper	NOUN
admet-2088	174	8	telluride	telluride	NOUN
admet-2088	174	9	nanoparticles	nanoparticle	NOUN
admet-2088	174	10	,	,	PUNCT
admet-2088	174	11	mpn	mpn	NOUN
admet-2088	174	12	:	:	PUNCT
admet-2088	174	13	metal	metal	NOUN
admet-2088	174	14	polyphenol	polyphenol	NOUN
admet-2088	174	15	complex	complex	NOUN
admet-2088	174	16	,	,	PUNCT
admet-2088	174	17	mcn	mcn	PROPN
admet-2088	174	18	:	:	PUNCT
admet-2088	174	19	mobil	mobil	NOUN
admet-2088	174	20	composition	composition	NOUN
admet-2088	174	21	of	of	ADP
admet-2088	174	22	matter	matter	NOUN
admet-2088	174	23	,	,	PUNCT
admet-2088	174	24	swcnt	swcnt	ADP
admet-2088	174	25	:	:	PUNCT
admet-2088	174	26	single	single	ADJ
admet-2088	174	27	-	-	PUNCT
admet-2088	174	28	walled	wall	VERB
admet-2088	174	29	carbon	carbon	NOUN
admet-2088	174	30	nanotubes	nanotube	NOUN
admet-2088	174	31	,	,	PUNCT
admet-2088	174	32	mwcnt	mwcnt	ADV
admet-2088	174	33	:	:	PUNCT
admet-2088	174	34	multiwalled	multiwalle	VERB
admet-2088	174	35	carbon	carbon	NOUN
admet-2088	174	36	nanotubes	nanotube	NOUN
admet-2088	174	37	metal	metal	NOUN
admet-2088	174	38	-	-	PUNCT
admet-2088	174	39	based	base	VERB
admet-2088	174	40	nanomaterials	nanomaterial	NOUN
admet-2088	174	41	metals	metal	NOUN
admet-2088	174	42	and	and	CCONJ
admet-2088	174	43	,	,	PUNCT
admet-2088	174	44	more	more	ADV
admet-2088	174	45	particularly	particularly	ADV
admet-2088	174	46	,	,	PUNCT
admet-2088	174	47	their	their	PRON
admet-2088	174	48	nano	nano	NOUN
admet-2088	174	49	species	specie	NOUN
admet-2088	174	50	have	have	AUX
admet-2088	174	51	shown	show	VERB
admet-2088	174	52	tremendous	tremendous	ADJ
admet-2088	174	53	potential	potential	NOUN
admet-2088	174	54	in	in	ADP
admet-2088	174	55	medical	medical	ADJ
admet-2088	174	56	research	research	NOUN
admet-2088	174	57	and	and	CCONJ
admet-2088	174	58	drug	drug	NOUN
admet-2088	174	59	delivery	delivery	NOUN
admet-2088	174	60	due	due	ADP
admet-2088	174	61	to	to	ADP
admet-2088	174	62	their	their	PRON
admet-2088	174	63	natural	natural	ADJ
admet-2088	174	64	availability	availability	NOUN
admet-2088	174	65	and	and	CCONJ
admet-2088	174	66	can	can	AUX
admet-2088	174	67	be	be	AUX
admet-2088	174	68	easily	easily	ADV
admet-2088	174	69	processed	process	VERB
admet-2088	174	70	into	into	ADP
admet-2088	174	71	their	their	PRON
admet-2088	174	72	nanostructures	nanostructure	NOUN
admet-2088	174	73	.	.	PUNCT
admet-2088	175	1	among	among	ADP
admet-2088	175	2	all	all	PRON
admet-2088	175	3	,	,	PUNCT
admet-2088	175	4	metal	metal	NOUN
admet-2088	175	5	and	and	CCONJ
admet-2088	175	6	their	their	PRON
admet-2088	175	7	oxides	oxide	NOUN
admet-2088	175	8	in	in	ADP
admet-2088	175	9	the	the	DET
admet-2088	175	10	form	form	NOUN
admet-2088	175	11	of	of	ADP
admet-2088	175	12	nps	nps	PROPN
admet-2088	175	13	have	have	VERB
admet-2088	175	14	great	great	ADJ
admet-2088	175	15	potential	potential	NOUN
admet-2088	175	16	not	not	PART
admet-2088	175	17	only	only	ADV
admet-2088	175	18	in	in	ADP
admet-2088	175	19	the	the	DET
admet-2088	175	20	treatment	treatment	NOUN
admet-2088	175	21	of	of	ADP
admet-2088	175	22	diseases	disease	NOUN
admet-2088	175	23	but	but	CCONJ
admet-2088	175	24	also	also	ADV
admet-2088	175	25	in	in	ADP
admet-2088	175	26	carrying	carry	VERB
admet-2088	175	27	drug	drug	NOUN
admet-2088	175	28	molecules	molecule	NOUN
admet-2088	175	29	for	for	ADP
admet-2088	175	30	targeted	target	VERB
admet-2088	175	31	drug	drug	NOUN
admet-2088	175	32	delivery	delivery	NOUN
admet-2088	175	33	in	in	ADP
admet-2088	175	34	the	the	DET
admet-2088	175	35	case	case	NOUN
admet-2088	175	36	of	of	ADP
admet-2088	175	37	specific	specific	ADJ
admet-2088	175	38	diseases	disease	NOUN
admet-2088	175	39	such	such	ADJ
admet-2088	175	40	as	as	ADP
admet-2088	175	41	cancers	cancer	NOUN
admet-2088	175	42	.	.	PUNCT
admet-2088	176	1	out	out	ADP
admet-2088	176	2	of	of	ADP
admet-2088	176	3	various	various	ADJ
admet-2088	176	4	metals	metal	NOUN
admet-2088	176	5	,	,	PUNCT
admet-2088	176	6	gold	gold	NOUN
admet-2088	176	7	,	,	PUNCT
admet-2088	176	8	silver	silver	NOUN
admet-2088	176	9	,	,	PUNCT
admet-2088	176	10	copper	copper	NOUN
admet-2088	176	11	,	,	PUNCT
admet-2088	176	12	platinum	platinum	NOUN
admet-2088	176	13	,	,	PUNCT
admet-2088	176	14	silica	silica	NOUN
admet-2088	176	15	,	,	PUNCT
admet-2088	176	16	titanium	titanium	NOUN
admet-2088	176	17	dioxide	dioxide	NOUN
admet-2088	176	18	(	(	PUNCT
admet-2088	176	19	tio2	tio2	NOUN
admet-2088	176	20	)	)	PUNCT
admet-2088	176	21	and	and	CCONJ
admet-2088	176	22	iron	iron	NOUN
admet-2088	176	23	-	-	PUNCT
admet-2088	176	24	based	base	VERB
admet-2088	176	25	nms	nms	NOUN
admet-2088	176	26	are	be	AUX
admet-2088	176	27	used	use	VERB
admet-2088	176	28	in	in	ADP
admet-2088	176	29	the	the	DET
admet-2088	176	30	treatment	treatment	NOUN
admet-2088	176	31	of	of	ADP
admet-2088	176	32	melanoma	melanoma	NOUN
admet-2088	176	33	and	and	CCONJ
admet-2088	176	34	are	be	AUX
admet-2088	176	35	discussed	discuss	VERB
admet-2088	176	36	below	below	ADV
admet-2088	176	37	.	.	PUNCT
admet-2088	177	1	gold	gold	ADJ
admet-2088	177	2	nanoparticles	nanoparticle	NOUN
admet-2088	177	3	in	in	ADP
admet-2088	177	4	1857	1857	NUM
admet-2088	177	5	,	,	PUNCT
admet-2088	177	6	michael	michael	PROPN
admet-2088	177	7	faraday	faraday	PROPN
admet-2088	177	8	first	first	ADV
admet-2088	177	9	reported	report	VERB
admet-2088	177	10	gold	gold	PROPN
admet-2088	177	11	nps	nps	PROPN
admet-2088	177	12	,	,	PUNCT
admet-2088	177	13	producing	produce	VERB
admet-2088	177	14	colloidal	colloidal	NOUN
admet-2088	177	15	gold	gold	NOUN
admet-2088	177	16	through	through	ADP
admet-2088	177	17	the	the	DET
admet-2088	177	18	reduction	reduction	NOUN
admet-2088	177	19	reaction	reaction	NOUN
admet-2088	177	20	of	of	ADP
admet-2088	177	21	gold	gold	ADJ
admet-2088	177	22	salts	salt	NOUN
admet-2088	177	23	[	[	X
admet-2088	177	24	73	73	NUM
admet-2088	177	25	]	]	PUNCT
admet-2088	177	26	.	.	PUNCT
admet-2088	178	1	however	however	ADV
admet-2088	178	2	,	,	PUNCT
admet-2088	178	3	the	the	DET
admet-2088	178	4	therapeutic	therapeutic	ADJ
admet-2088	178	5	application	application	NOUN
admet-2088	178	6	of	of	ADP
admet-2088	178	7	gold	gold	NOUN
admet-2088	178	8	in	in	ADP
admet-2088	178	9	the	the	DET
admet-2088	178	10	treatment	treatment	NOUN
admet-2088	178	11	of	of	ADP
admet-2088	178	12	rheumatoid	rheumatoid	NOUN
admet-2088	178	13	arthritis	arthritis	NOUN
admet-2088	178	14	was	be	AUX
admet-2088	178	15	performed	perform	VERB
admet-2088	178	16	in	in	ADP
admet-2088	178	17	1927	1927	NUM
admet-2088	178	18	[	[	X
admet-2088	178	19	74	74	NUM
admet-2088	178	20	]	]	PUNCT
admet-2088	178	21	,	,	PUNCT
admet-2088	178	22	followed	follow	VERB
admet-2088	178	23	by	by	ADP
admet-2088	178	24	the	the	DET
admet-2088	178	25	use	use	NOUN
admet-2088	178	26	of	of	ADP
admet-2088	178	27	nanogold	nanogold	NOUN
admet-2088	178	28	against	against	ADP
admet-2088	178	29	various	various	ADJ
admet-2088	178	30	rheumatoid	rheumatoid	NOUN
admet-2088	178	31	diseases	disease	NOUN
admet-2088	178	32	.	.	PUNCT
admet-2088	179	1	gold	gold	PROPN
admet-2088	179	2	nps	nps	PROPN
admet-2088	179	3	have	have	AUX
admet-2088	179	4	been	be	AUX
admet-2088	179	5	explored	explore	VERB
admet-2088	179	6	in	in	ADP
admet-2088	179	7	the	the	DET
admet-2088	179	8	treatment	treatment	NOUN
admet-2088	179	9	of	of	ADP
admet-2088	179	10	various	various	ADJ
admet-2088	179	11	diseases	disease	NOUN
admet-2088	179	12	due	due	ADJ
admet-2088	179	13	to	to	ADP
admet-2088	179	14	(	(	PUNCT
admet-2088	179	15	i	i	NOUN
admet-2088	179	16	)	)	PUNCT
admet-2088	179	17	precise	precise	ADJ
admet-2088	179	18	control	control	NOUN
admet-2088	179	19	over	over	ADP
admet-2088	179	20	their	their	PRON
admet-2088	179	21	particle	particle	NOUN
admet-2088	179	22	size	size	NOUN
admet-2088	179	23	distribution	distribution	NOUN
admet-2088	179	24	,	,	PUNCT
admet-2088	179	25	(	(	PUNCT
admet-2088	179	26	ii	ii	NOUN
admet-2088	179	27	)	)	PUNCT
admet-2088	179	28	allowing	allow	VERB
admet-2088	179	29	the	the	DET
admet-2088	179	30	modification	modification	NOUN
admet-2088	179	31	of	of	ADP
admet-2088	179	32	shapes	shape	NOUN
admet-2088	179	33	to	to	PART
admet-2088	179	34	produce	produce	VERB
admet-2088	179	35	cubes	cube	NOUN
admet-2088	179	36	,	,	PUNCT
admet-2088	179	37	nanoclusters	nanocluster	NOUN
admet-2088	179	38	,	,	PUNCT
admet-2088	179	39	nanorods	nanorod	NOUN
admet-2088	179	40	,	,	PUNCT
admet-2088	179	41	spheres	sphere	NOUN
admet-2088	179	42	,	,	PUNCT
admet-2088	179	43	nanoprisms	nanoprism	NOUN
admet-2088	179	44	,	,	PUNCT
admet-2088	179	45	hexagonal	hexagonal	ADJ
admet-2088	179	46	platelets	platelet	NOUN
admet-2088	179	47	,	,	PUNCT
admet-2088	179	48	etc	etc	X
admet-2088	179	49	.	.	X
admet-2088	179	50	,	,	PUNCT
admet-2088	179	51	(	(	PUNCT
admet-2088	179	52	iii	iii	X
admet-2088	179	53	)	)	PUNCT
admet-2088	179	54	biocompatible	biocompatible	NOUN
admet-2088	179	55	inside	inside	ADP
admet-2088	179	56	the	the	DET
admet-2088	179	57	mammalian	mammalian	ADJ
admet-2088	179	58	cell	cell	NOUN
admet-2088	179	59	as	as	SCONJ
admet-2088	179	60	they	they	PRON
admet-2088	179	61	are	be	AUX
admet-2088	179	62	inactive	inactive	ADJ
admet-2088	179	63	and	and	CCONJ
admet-2088	179	64	not	not	PART
admet-2088	179	65	potentially	potentially	ADV
admet-2088	179	66	separate	separate	ADJ
admet-2088	179	67	into	into	ADP
admet-2088	179	68	particles	particle	NOUN
admet-2088	179	69	[	[	X
admet-2088	179	70	75	75	NUM
admet-2088	179	71	]	]	PUNCT
admet-2088	179	72	,	,	PUNCT
admet-2088	179	73	(	(	PUNCT
admet-2088	179	74	iv	iv	X
admet-2088	179	75	)	)	PUNCT
admet-2088	179	76	surface	surface	NOUN
admet-2088	179	77	modification	modification	NOUN
admet-2088	179	78	through	through	ADP
admet-2088	179	79	conjugation	conjugation	NOUN
admet-2088	179	80	with	with	ADP
admet-2088	179	81	therapeutic	therapeutic	ADJ
admet-2088	179	82	molecules	molecule	NOUN
admet-2088	179	83	,	,	PUNCT
admet-2088	179	84	molecular	molecular	ADJ
admet-2088	179	85	probe	probe	NOUN
admet-2088	179	86	,	,	PUNCT
admet-2088	179	87	antibodies	antibodie	VERB
admet-2088	179	88	,	,	PUNCT
admet-2088	179	89	various	various	ADJ
admet-2088	179	90	polymers	polymer	NOUN
admet-2088	179	91	,	,	PUNCT
admet-2088	179	92	etc	etc	X
admet-2088	179	93	.	.	X
admet-2088	180	1	[	[	X
admet-2088	180	2	76	76	NUM
admet-2088	180	3	]	]	X
admet-2088	180	4	,	,	PUNCT
admet-2088	180	5	and	and	CCONJ
admet-2088	180	6	(	(	PUNCT
admet-2088	180	7	v	v	NOUN
admet-2088	180	8	)	)	PUNCT
admet-2088	180	9	extraordinary	extraordinary	ADJ
admet-2088	180	10	colloidal	colloidal	NOUN
admet-2088	180	11	stability	stability	NOUN
admet-2088	180	12	admet	admet	PROPN
admet-2088	180	13	&	&	CCONJ
admet-2088	180	14	dmpk	dmpk	PROPN
admet-2088	180	15	12(1	12(1	PROPN
admet-2088	180	16	)	)	PUNCT
admet-2088	180	17	(	(	PUNCT
admet-2088	180	18	2024	2024	NUM
admet-2088	180	19	)	)	PUNCT
admet-2088	180	20	107	107	NUM
admet-2088	180	21	-	-	SYM
admet-2088	180	22	150	150	NUM
admet-2088	180	23	nanomaterial	nanomaterial	NOUN
admet-2088	180	24	-	-	PUNCT
admet-2088	180	25	based	base	VERB
admet-2088	180	26	drug	drug	NOUN
admet-2088	180	27	delivery	delivery	NOUN
admet-2088	180	28	systems	system	NOUN
admet-2088	180	29	for	for	ADP
admet-2088	180	30	melanoma	melanoma	NOUN
admet-2088	180	31	therapy	therapy	NOUN
admet-2088	180	32	doi	doi	NOUN
admet-2088	180	33	:	:	PUNCT
admet-2088	180	34	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	180	35	115	115	NUM
admet-2088	180	36	and	and	CCONJ
admet-2088	180	37	tuneable	tuneable	ADJ
admet-2088	180	38	optical	optical	ADJ
admet-2088	180	39	characteristics	characteristic	NOUN
admet-2088	180	40	.	.	PUNCT
admet-2088	181	1	in	in	ADP
admet-2088	181	2	cancer	cancer	NOUN
admet-2088	181	3	treatment	treatment	NOUN
admet-2088	181	4	,	,	PUNCT
admet-2088	181	5	high	high	ADJ
admet-2088	181	6	tissue	tissue	NOUN
admet-2088	181	7	permeability	permeability	NOUN
admet-2088	181	8	,	,	PUNCT
admet-2088	181	9	biocompatibility	biocompatibility	NOUN
admet-2088	181	10	and	and	CCONJ
admet-2088	181	11	bioconjugation	bioconjugation	NOUN
admet-2088	181	12	play	play	VERB
admet-2088	181	13	crucial	crucial	ADJ
admet-2088	181	14	roles	role	NOUN
admet-2088	181	15	.	.	PUNCT
admet-2088	182	1	the	the	DET
admet-2088	182	2	positive	positive	ADJ
admet-2088	182	3	charge	charge	NOUN
admet-2088	182	4	on	on	ADP
admet-2088	182	5	the	the	DET
admet-2088	182	6	surface	surface	NOUN
admet-2088	182	7	of	of	ADP
admet-2088	182	8	gold	gold	PROPN
admet-2088	182	9	nps	nps	PROPN
admet-2088	182	10	facilitates	facilitate	VERB
admet-2088	182	11	their	their	PRON
admet-2088	182	12	internalization	internalization	NOUN
admet-2088	182	13	by	by	ADP
admet-2088	182	14	the	the	DET
admet-2088	182	15	cell	cell	NOUN
admet-2088	182	16	membrane	membrane	NOUN
admet-2088	182	17	,	,	PUNCT
admet-2088	182	18	which	which	PRON
admet-2088	182	19	is	be	AUX
admet-2088	182	20	negatively	negatively	ADV
admet-2088	182	21	charged	charge	VERB
admet-2088	182	22	due	due	ADP
admet-2088	182	23	to	to	ADP
admet-2088	182	24	the	the	DET
admet-2088	182	25	presence	presence	NOUN
admet-2088	182	26	of	of	ADP
admet-2088	182	27	lipids	lipid	NOUN
admet-2088	182	28	.	.	PUNCT
admet-2088	183	1	in	in	ADP
admet-2088	183	2	addition	addition	NOUN
admet-2088	183	3	,	,	PUNCT
admet-2088	183	4	they	they	PRON
admet-2088	183	5	are	be	AUX
admet-2088	183	6	steady	steady	ADJ
admet-2088	183	7	against	against	ADP
admet-2088	183	8	oxidation	oxidation	NOUN
admet-2088	183	9	under	under	ADP
admet-2088	183	10	physiological	physiological	ADJ
admet-2088	183	11	conditions	condition	NOUN
admet-2088	183	12	such	such	ADJ
admet-2088	183	13	as	as	ADP
admet-2088	183	14	temperature	temperature	NOUN
admet-2088	183	15	,	,	PUNCT
admet-2088	183	16	ph	ph	ADJ
admet-2088	183	17	conditions	condition	NOUN
admet-2088	183	18	and	and	CCONJ
admet-2088	183	19	ionic	ionic	ADJ
admet-2088	183	20	strength	strength	NOUN
admet-2088	184	1	[	[	X
admet-2088	184	2	77,78	77,78	NOUN
admet-2088	184	3	]	]	PUNCT
admet-2088	184	4	.	.	PUNCT
admet-2088	185	1	they	they	PRON
admet-2088	185	2	can	can	AUX
admet-2088	185	3	be	be	AUX
admet-2088	185	4	selectively	selectively	ADV
admet-2088	185	5	transported	transport	VERB
admet-2088	185	6	and	and	CCONJ
admet-2088	185	7	precisely	precisely	ADV
admet-2088	185	8	targeted	target	VERB
admet-2088	185	9	using	use	VERB
admet-2088	185	10	both	both	CCONJ
admet-2088	185	11	active	active	ADJ
admet-2088	185	12	and	and	CCONJ
admet-2088	185	13	passive	passive	ADJ
admet-2088	185	14	targeting	targeting	NOUN
admet-2088	185	15	approaches	approach	NOUN
admet-2088	185	16	.	.	PUNCT
admet-2088	186	1	the	the	DET
admet-2088	186	2	accumulation	accumulation	NOUN
admet-2088	186	3	of	of	ADP
admet-2088	186	4	gold	gold	PROPN
admet-2088	186	5	nps	nps	PROPN
admet-2088	186	6	in	in	ADP
admet-2088	186	7	the	the	DET
admet-2088	186	8	tumour	tumour	NOUN
admet-2088	186	9	tissue	tissue	NOUN
admet-2088	186	10	is	be	AUX
admet-2088	186	11	due	due	ADJ
admet-2088	186	12	to	to	ADP
admet-2088	186	13	the	the	DET
admet-2088	186	14	enhanced	enhanced	ADJ
admet-2088	186	15	permeability	permeability	NOUN
admet-2088	186	16	and	and	CCONJ
admet-2088	186	17	retention	retention	NOUN
admet-2088	186	18	(	(	PUNCT
admet-2088	186	19	epr	epr	ADJ
admet-2088	186	20	)	)	PUNCT
admet-2088	186	21	effect	effect	NOUN
admet-2088	186	22	(	(	PUNCT
admet-2088	186	23	the	the	DET
admet-2088	186	24	mechanism	mechanism	NOUN
admet-2088	186	25	due	due	ADP
admet-2088	186	26	to	to	ADP
admet-2088	186	27	which	which	PRON
admet-2088	186	28	high	high	ADJ
admet-2088	186	29	-	-	PUNCT
admet-2088	186	30	molecular	molecular	ADJ
admet-2088	186	31	weight	weight	NOUN
admet-2088	186	32	non	non	ADJ
admet-2088	186	33	-	-	ADJ
admet-2088	186	34	targeted	targeted	ADJ
admet-2088	186	35	drugs	drug	NOUN
admet-2088	186	36	and	and	CCONJ
admet-2088	186	37	prodrugs	prodrug	NOUN
admet-2088	186	38	accumulated	accumulate	VERB
admet-2088	186	39	in	in	ADP
admet-2088	186	40	the	the	DET
admet-2088	186	41	tissues	tissue	NOUN
admet-2088	186	42	that	that	PRON
admet-2088	186	43	exhibited	exhibit	VERB
admet-2088	186	44	increased	increase	VERB
admet-2088	186	45	vascular	vascular	ADJ
admet-2088	186	46	permeability	permeability	NOUN
admet-2088	186	47	)	)	PUNCT
admet-2088	186	48	and	and	CCONJ
admet-2088	186	49	subsequently	subsequently	ADV
admet-2088	186	50	,	,	PUNCT
admet-2088	186	51	taken	take	VERB
admet-2088	186	52	up	up	ADP
admet-2088	186	53	by	by	ADP
admet-2088	186	54	cells	cell	NOUN
admet-2088	186	55	through	through	ADP
admet-2088	186	56	the	the	DET
admet-2088	186	57	endocytosis	endocytosis	NOUN
admet-2088	186	58	process	process	NOUN
admet-2088	186	59	[	[	X
admet-2088	186	60	79	79	NUM
admet-2088	186	61	]	]	PUNCT
admet-2088	186	62	.	.	PUNCT
admet-2088	187	1	gold	gold	NOUN
admet-2088	187	2	nms	nms	PROPN
admet-2088	187	3	have	have	AUX
admet-2088	187	4	been	be	AUX
admet-2088	187	5	utilized	utilize	VERB
admet-2088	187	6	in	in	ADP
admet-2088	187	7	various	various	ADJ
admet-2088	187	8	forms	form	NOUN
admet-2088	187	9	,	,	PUNCT
admet-2088	187	10	such	such	ADJ
admet-2088	187	11	as	as	ADP
admet-2088	187	12	nps	nps	PROPN
admet-2088	187	13	,	,	PUNCT
admet-2088	187	14	nanorods	nanorod	NOUN
admet-2088	187	15	,	,	PUNCT
admet-2088	187	16	nanoclusters	nanocluster	NOUN
admet-2088	187	17	,	,	PUNCT
admet-2088	187	18	nanoshells	nanoshell	NOUN
admet-2088	187	19	,	,	PUNCT
admet-2088	187	20	nanocomposites	nanocomposite	NOUN
admet-2088	187	21	,	,	PUNCT
admet-2088	187	22	nanocages	nanocage	NOUN
admet-2088	187	23	and	and	CCONJ
admet-2088	187	24	so	so	ADV
admet-2088	187	25	on	on	ADV
admet-2088	187	26	for	for	ADP
admet-2088	187	27	drug	drug	NOUN
admet-2088	187	28	delivery	delivery	NOUN
admet-2088	187	29	in	in	ADP
admet-2088	187	30	the	the	DET
admet-2088	187	31	treatment	treatment	NOUN
admet-2088	187	32	of	of	ADP
admet-2088	187	33	melanoma	melanoma	NOUN
admet-2088	187	34	.	.	PUNCT
admet-2088	188	1	a	a	DET
admet-2088	188	2	few	few	ADJ
admet-2088	188	3	important	important	ADJ
admet-2088	188	4	and	and	CCONJ
admet-2088	188	5	recent	recent	ADJ
admet-2088	188	6	studies	study	NOUN
admet-2088	188	7	regarding	regard	VERB
admet-2088	188	8	the	the	DET
admet-2088	188	9	use	use	NOUN
admet-2088	188	10	of	of	ADP
admet-2088	188	11	gold	gold	ADJ
admet-2088	188	12	nms	nms	NOUN
admet-2088	188	13	as	as	SCONJ
admet-2088	188	14	carriers	carrier	NOUN
admet-2088	188	15	to	to	PART
admet-2088	188	16	deliver	deliver	VERB
admet-2088	188	17	drugs	drug	NOUN
admet-2088	188	18	to	to	ADP
admet-2088	188	19	melanoma	melanoma	NOUN
admet-2088	188	20	sites	site	NOUN
admet-2088	188	21	are	be	AUX
admet-2088	188	22	presented	present	VERB
admet-2088	188	23	below	below	ADV
admet-2088	188	24	.	.	PUNCT
admet-2088	189	1	gold	gold	NOUN
admet-2088	189	2	nanoclusters	nanocluster	NOUN
admet-2088	189	3	have	have	VERB
admet-2088	189	4	great	great	ADJ
admet-2088	189	5	potential	potential	NOUN
admet-2088	189	6	for	for	ADP
admet-2088	189	7	application	application	NOUN
admet-2088	189	8	in	in	ADP
admet-2088	189	9	the	the	DET
admet-2088	189	10	biomedical	biomedical	ADJ
admet-2088	189	11	field	field	NOUN
admet-2088	189	12	due	due	ADP
admet-2088	189	13	to	to	ADP
admet-2088	189	14	their	their	PRON
admet-2088	189	15	promising	promising	ADJ
admet-2088	189	16	optical	optical	ADJ
admet-2088	189	17	properties	property	NOUN
admet-2088	189	18	.	.	PUNCT
admet-2088	190	1	based	base	VERB
admet-2088	190	2	on	on	ADP
admet-2088	190	3	this	this	PRON
admet-2088	190	4	,	,	PUNCT
admet-2088	190	5	latorre	latorre	PROPN
admet-2088	190	6	et	et	PROPN
admet-2088	190	7	al	al	PROPN
admet-2088	190	8	.	.	PUNCT
admet-2088	191	1	[	[	X
admet-2088	191	2	80	80	NUM
admet-2088	191	3	]	]	PUNCT
admet-2088	191	4	fabricated	fabricate	VERB
admet-2088	191	5	albumin	albumin	NOUN
admet-2088	191	6	-	-	PUNCT
admet-2088	191	7	stabilized	stabilize	VERB
admet-2088	191	8	gold	gold	NOUN
admet-2088	191	9	nanoclusters	nanocluster	NOUN
admet-2088	191	10	(	(	PUNCT
admet-2088	191	11	albuminbased	albuminbase	VERB
admet-2088	191	12	nanostructures	nanostructure	NOUN
admet-2088	191	13	)	)	PUNCT
admet-2088	191	14	loaded	load	VERB
admet-2088	191	15	with	with	ADP
admet-2088	191	16	azd8055	azd8055	NOUN
admet-2088	191	17	,	,	PUNCT
admet-2088	191	18	a	a	DET
admet-2088	191	19	potent	potent	NOUN
admet-2088	191	20	,	,	PUNCT
admet-2088	191	21	selective	selective	ADJ
admet-2088	191	22	atp	atp	NOUN
admet-2088	191	23	-	-	PUNCT
admet-2088	191	24	competitive	competitive	ADJ
admet-2088	191	25	mammalian	mammalian	ADJ
admet-2088	191	26	target	target	NOUN
admet-2088	191	27	of	of	ADP
admet-2088	191	28	rapamycin	rapamycin	NOUN
admet-2088	191	29	(	(	PUNCT
admet-2088	191	30	mtor	mtor	PROPN
admet-2088	191	31	)	)	PUNCT
admet-2088	191	32	kinase	kinase	PROPN
admet-2088	191	33	inhibitor	inhibitor	NOUN
admet-2088	191	34	,	,	PUNCT
admet-2088	191	35	for	for	ADP
admet-2088	191	36	its	its	PRON
admet-2088	191	37	specific	specific	ADJ
admet-2088	191	38	delivery	delivery	NOUN
admet-2088	191	39	into	into	ADP
admet-2088	191	40	uveal	uveal	ADJ
admet-2088	191	41	melanoma	melanoma	NOUN
admet-2088	191	42	.	.	PUNCT
admet-2088	192	1	in	in	ADP
admet-2088	192	2	this	this	PRON
admet-2088	192	3	,	,	PUNCT
admet-2088	192	4	the	the	DET
admet-2088	192	5	nanostructure	nanostructure	NOUN
admet-2088	192	6	having	have	VERB
admet-2088	192	7	low	low	ADJ
admet-2088	192	8	toxicity	toxicity	NOUN
admet-2088	192	9	and	and	CCONJ
admet-2088	192	10	exceptional	exceptional	ADJ
admet-2088	192	11	stability	stability	NOUN
admet-2088	192	12	in	in	ADP
admet-2088	192	13	vivo	vivo	NOUN
admet-2088	192	14	is	be	AUX
admet-2088	192	15	conjugated	conjugate	VERB
admet-2088	192	16	with	with	ADP
admet-2088	192	17	the	the	DET
admet-2088	192	18	drug	drug	NOUN
admet-2088	192	19	employing	employ	VERB
admet-2088	192	20	a	a	DET
admet-2088	192	21	disulfide	disulfide	NOUN
admet-2088	192	22	moietycontaining	moietycontaining	NOUN
admet-2088	192	23	linker	linker	NOUN
admet-2088	192	24	.	.	PUNCT
admet-2088	193	1	as	as	ADP
admet-2088	193	2	a	a	DET
admet-2088	193	3	result	result	NOUN
admet-2088	193	4	,	,	PUNCT
admet-2088	193	5	the	the	DET
admet-2088	193	6	drug	drug	NOUN
admet-2088	193	7	was	be	AUX
admet-2088	193	8	released	release	VERB
admet-2088	193	9	selectively	selectively	ADV
admet-2088	193	10	and	and	CCONJ
admet-2088	193	11	effectively	effectively	ADV
admet-2088	193	12	in	in	ADP
admet-2088	193	13	the	the	DET
admet-2088	193	14	tumoral	tumoral	ADJ
admet-2088	193	15	cells	cell	NOUN
admet-2088	193	16	in	in	ADP
admet-2088	193	17	the	the	DET
admet-2088	193	18	presence	presence	NOUN
admet-2088	193	19	of	of	ADP
admet-2088	193	20	a	a	DET
admet-2088	193	21	higher	high	ADJ
admet-2088	193	22	concentration	concentration	NOUN
admet-2088	193	23	of	of	ADP
admet-2088	193	24	glutathione	glutathione	NOUN
admet-2088	193	25	.	.	PUNCT
admet-2088	194	1	the	the	DET
admet-2088	194	2	robust	robust	ADJ
admet-2088	194	3	nanostructure	nanostructure	NOUN
admet-2088	194	4	induced	induce	VERB
admet-2088	194	5	significant	significant	ADJ
admet-2088	194	6	cellular	cellular	ADJ
admet-2088	194	7	toxicity	toxicity	NOUN
admet-2088	194	8	without	without	ADP
admet-2088	194	9	affecting	affect	VERB
admet-2088	194	10	non	non	ADJ
admet-2088	194	11	-	-	ADJ
admet-2088	194	12	tumoral	tumoral	ADJ
admet-2088	194	13	keratinocytes	keratinocyte	NOUN
admet-2088	194	14	.	.	PUNCT
admet-2088	195	1	further	far	ADV
admet-2088	195	2	,	,	PUNCT
admet-2088	195	3	these	these	DET
admet-2088	195	4	nanostructures	nanostructure	NOUN
admet-2088	195	5	demonstrated	demonstrate	VERB
admet-2088	195	6	excellent	excellent	ADJ
admet-2088	195	7	in	in	ADP
admet-2088	195	8	vivo	vivo	ADJ
admet-2088	195	9	activity	activity	NOUN
admet-2088	195	10	by	by	ADP
admet-2088	195	11	decreasing	decrease	VERB
admet-2088	195	12	the	the	DET
admet-2088	195	13	tumour	tumour	NOUN
admet-2088	195	14	surface	surface	NOUN
admet-2088	195	15	compared	compare	VERB
admet-2088	195	16	to	to	ADP
admet-2088	195	17	the	the	DET
admet-2088	195	18	free	free	ADJ
admet-2088	195	19	drug	drug	NOUN
admet-2088	195	20	in	in	ADP
admet-2088	195	21	the	the	DET
admet-2088	195	22	mice	mouse	NOUN
admet-2088	195	23	model	model	NOUN
admet-2088	195	24	.	.	PUNCT
admet-2088	196	1	these	these	DET
admet-2088	196	2	nanostructures	nanostructure	NOUN
admet-2088	196	3	have	have	VERB
admet-2088	196	4	the	the	DET
admet-2088	196	5	capability	capability	NOUN
admet-2088	196	6	of	of	ADP
admet-2088	196	7	providing	provide	VERB
admet-2088	196	8	the	the	DET
admet-2088	196	9	same	same	ADJ
admet-2088	196	10	result	result	NOUN
admet-2088	196	11	,	,	PUNCT
admet-2088	196	12	employing	employ	VERB
admet-2088	196	13	23	23	NUM
admet-2088	196	14	times	time	NOUN
admet-2088	196	15	lower	low	ADJ
admet-2088	196	16	doses	dose	NOUN
admet-2088	196	17	than	than	ADP
admet-2088	196	18	those	those	PRON
admet-2088	196	19	employed	employ	VERB
admet-2088	196	20	in	in	ADP
admet-2088	196	21	the	the	DET
admet-2088	196	22	previous	previous	ADJ
admet-2088	196	23	study	study	NOUN
admet-2088	196	24	.	.	PUNCT
admet-2088	197	1	in	in	ADP
admet-2088	197	2	one	one	NUM
admet-2088	197	3	study	study	NOUN
admet-2088	197	4	,	,	PUNCT
admet-2088	197	5	biocompatible	biocompatible	ADJ
admet-2088	197	6	gold	gold	PROPN
admet-2088	197	7	nps	nps	PROPN
admet-2088	197	8	were	be	AUX
admet-2088	197	9	biosynthesized	biosynthesize	VERB
admet-2088	197	10	with	with	ADP
admet-2088	197	11	an	an	DET
admet-2088	197	12	aqueous	aqueous	ADJ
admet-2088	197	13	extract	extract	NOUN
admet-2088	197	14	of	of	ADP
admet-2088	197	15	siberian	siberian	ADJ
admet-2088	197	16	ginseng	ginseng	NOUN
admet-2088	197	17	(	(	PUNCT
admet-2088	197	18	sg	sg	NOUN
admet-2088	197	19	-	-	PUNCT
admet-2088	197	20	gnps	gnps	NOUN
admet-2088	197	21	)	)	PUNCT
admet-2088	197	22	in	in	ADP
admet-2088	197	23	a	a	DET
admet-2088	197	24	cost	cost	NOUN
admet-2088	197	25	-	-	PUNCT
admet-2088	197	26	effective	effective	ADJ
admet-2088	197	27	manner	manner	NOUN
admet-2088	197	28	.	.	PUNCT
admet-2088	198	1	the	the	DET
admet-2088	198	2	biological	biological	ADJ
admet-2088	198	3	ingredients	ingredient	NOUN
admet-2088	198	4	in	in	ADP
admet-2088	198	5	siberian	siberian	ADJ
admet-2088	198	6	ginseng	ginseng	PROPN
admet-2088	198	7	act	act	NOUN
admet-2088	198	8	as	as	ADP
admet-2088	198	9	a	a	DET
admet-2088	198	10	reducing	reduce	VERB
admet-2088	198	11	agent	agent	NOUN
admet-2088	198	12	,	,	PUNCT
admet-2088	198	13	reducing	reduce	VERB
admet-2088	198	14	gold	gold	NOUN
admet-2088	198	15	ions	ion	NOUN
admet-2088	198	16	to	to	ADP
admet-2088	198	17	gold	gold	PROPN
admet-2088	198	18	nps	nps	PROPN
admet-2088	198	19	.	.	PUNCT
admet-2088	199	1	the	the	DET
admet-2088	199	2	active	active	ADJ
admet-2088	199	3	ingredient	ingredient	NOUN
admet-2088	199	4	chalcones	chalcone	NOUN
admet-2088	199	5	present	present	ADJ
admet-2088	199	6	in	in	ADP
admet-2088	199	7	siberian	siberian	ADJ
admet-2088	199	8	ginseng	ginseng	NOUN
admet-2088	199	9	has	have	AUX
admet-2088	199	10	demonstrated	demonstrate	VERB
admet-2088	199	11	antitumor	antitumor	PROPN
admet-2088	199	12	activity	activity	NOUN
admet-2088	199	13	against	against	ADP
admet-2088	199	14	murine	murine	ADJ
admet-2088	199	15	melanoma	melanoma	NOUN
admet-2088	199	16	[	[	X
admet-2088	199	17	81	81	NUM
admet-2088	199	18	]	]	PUNCT
admet-2088	199	19	.	.	PUNCT
admet-2088	200	1	the	the	DET
admet-2088	200	2	biosynthesized	biosynthesize	VERB
admet-2088	200	3	gold	gold	PROPN
admet-2088	200	4	nps	nps	PROPN
admet-2088	200	5	fulfilled	fulfil	VERB
admet-2088	200	6	all	all	DET
admet-2088	200	7	the	the	DET
admet-2088	200	8	properties	property	NOUN
admet-2088	200	9	of	of	ADP
admet-2088	200	10	the	the	DET
admet-2088	200	11	gold	gold	PROPN
admet-2088	200	12	nps	nps	PROPN
admet-2088	200	13	,	,	PUNCT
admet-2088	200	14	including	include	VERB
admet-2088	200	15	spherical	spherical	ADJ
admet-2088	200	16	shape	shape	NOUN
admet-2088	200	17	and	and	CCONJ
admet-2088	200	18	crystalline	crystalline	ADJ
admet-2088	200	19	nature	nature	NOUN
admet-2088	200	20	.	.	PUNCT
admet-2088	201	1	the	the	DET
admet-2088	201	2	sg	sg	PROPN
admet-2088	201	3	-	-	PUNCT
admet-2088	201	4	gnps	gnps	ADJ
admet-2088	201	5	induced	induce	VERB
admet-2088	201	6	apoptosis	apoptosis	NOUN
admet-2088	201	7	of	of	ADP
admet-2088	201	8	melanoma	melanoma	NOUN
admet-2088	201	9	b16	b16	NOUN
admet-2088	201	10	cells	cell	NOUN
admet-2088	201	11	through	through	ADP
admet-2088	201	12	the	the	DET
admet-2088	201	13	generation	generation	NOUN
admet-2088	201	14	of	of	ADP
admet-2088	201	15	ros	ros	PROPN
admet-2088	201	16	and	and	CCONJ
admet-2088	201	17	a	a	DET
admet-2088	201	18	decrease	decrease	NOUN
admet-2088	201	19	in	in	ADP
admet-2088	201	20	mitochondrial	mitochondrial	ADJ
admet-2088	201	21	membrane	membrane	NOUN
admet-2088	201	22	potential	potential	NOUN
admet-2088	201	23	[	[	X
admet-2088	201	24	82	82	NUM
admet-2088	201	25	]	]	PUNCT
admet-2088	201	26	.	.	PUNCT
admet-2088	202	1	in	in	ADP
admet-2088	202	2	another	another	DET
admet-2088	202	3	study	study	NOUN
admet-2088	202	4	,	,	PUNCT
admet-2088	202	5	a	a	DET
admet-2088	202	6	combined	combined	ADJ
admet-2088	202	7	treatment	treatment	NOUN
admet-2088	202	8	of	of	ADP
admet-2088	202	9	chemotherapy	chemotherapy	NOUN
admet-2088	202	10	(	(	PUNCT
admet-2088	202	11	gold	gold	NOUN
admet-2088	202	12	-	-	PUNCT
admet-2088	202	13	paclitaxel	paclitaxel	NOUN
admet-2088	202	14	nps	nps	PROPN
admet-2088	202	15	)	)	PUNCT
admet-2088	202	16	and	and	CCONJ
admet-2088	202	17	sonodynamic	sonodynamic	ADJ
admet-2088	202	18	therapy	therapy	NOUN
admet-2088	202	19	(	(	PUNCT
admet-2088	202	20	sdt	sdt	PROPN
admet-2088	202	21	)	)	PUNCT
admet-2088	202	22	was	be	AUX
admet-2088	202	23	employed	employ	VERB
admet-2088	202	24	against	against	ADP
admet-2088	202	25	melanoma	melanoma	NOUN
admet-2088	202	26	therapy	therapy	NOUN
admet-2088	202	27	.	.	PUNCT
admet-2088	203	1	initially	initially	ADV
admet-2088	203	2	,	,	PUNCT
admet-2088	203	3	gold	gold	NOUN
admet-2088	203	4	-	-	PUNCT
admet-2088	203	5	paclitaxel	paclitaxel	PROPN
admet-2088	203	6	nps	nps	PROPN
admet-2088	203	7	were	be	AUX
admet-2088	203	8	synthesized	synthesize	VERB
admet-2088	203	9	and	and	CCONJ
admet-2088	203	10	found	find	VERB
admet-2088	203	11	to	to	PART
admet-2088	203	12	have	have	VERB
admet-2088	203	13	219.7±40.4	219.7±40.4	VERB
admet-2088	203	14	nm	nm	NOUN
admet-2088	203	15	in	in	ADP
admet-2088	203	16	size	size	NOUN
admet-2088	203	17	and	and	CCONJ
admet-2088	203	18	negative	negative	ADJ
admet-2088	203	19	zeta	zeta	NOUN
admet-2088	203	20	potential	potential	NOUN
admet-2088	203	21	,	,	PUNCT
admet-2088	203	22	indicating	indicate	VERB
admet-2088	203	23	a	a	DET
admet-2088	203	24	higher	high	ADJ
admet-2088	203	25	degree	degree	NOUN
admet-2088	203	26	of	of	ADP
admet-2088	203	27	stability	stability	NOUN
admet-2088	203	28	and	and	CCONJ
admet-2088	203	29	good	good	ADJ
admet-2088	203	30	dispersion	dispersion	NOUN
admet-2088	203	31	.	.	PUNCT
admet-2088	204	1	these	these	DET
admet-2088	204	2	nps	nps	PROPN
admet-2088	204	3	showed	show	VERB
admet-2088	204	4	promising	promising	ADJ
admet-2088	204	5	cytotoxicity	cytotoxicity	NOUN
admet-2088	204	6	against	against	ADP
admet-2088	204	7	c540	c540	PROPN
admet-2088	204	8	cancer	cancer	NOUN
admet-2088	204	9	cells	cell	NOUN
admet-2088	204	10	in	in	ADP
admet-2088	204	11	comparison	comparison	NOUN
admet-2088	204	12	to	to	ADP
admet-2088	204	13	free	free	ADJ
admet-2088	204	14	drugs	drug	NOUN
admet-2088	204	15	by	by	ADP
admet-2088	204	16	generating	generate	VERB
admet-2088	204	17	more	more	ADJ
admet-2088	204	18	ros	ro	NOUN
admet-2088	204	19	and	and	CCONJ
admet-2088	204	20	inducing	induce	VERB
admet-2088	204	21	apoptosis	apoptosis	NOUN
admet-2088	204	22	.	.	PUNCT
admet-2088	205	1	when	when	SCONJ
admet-2088	205	2	nps	nps	PROPN
admet-2088	205	3	were	be	AUX
admet-2088	205	4	combined	combine	VERB
admet-2088	205	5	with	with	ADP
admet-2088	205	6	sdt	sdt	PROPN
admet-2088	205	7	,	,	PUNCT
admet-2088	205	8	a	a	DET
admet-2088	205	9	synergistic	synergistic	ADJ
admet-2088	205	10	anticancer	anticancer	NOUN
admet-2088	205	11	effect	effect	NOUN
admet-2088	205	12	was	be	AUX
admet-2088	205	13	observed	observe	VERB
admet-2088	205	14	,	,	PUNCT
admet-2088	205	15	indicating	indicate	VERB
admet-2088	205	16	that	that	SCONJ
admet-2088	205	17	the	the	DET
admet-2088	205	18	gold	gold	PROPN
admet-2088	205	19	nps	nps	PROPN
admet-2088	205	20	are	be	AUX
admet-2088	205	21	excellent	excellent	ADJ
admet-2088	205	22	sonosensitizers	sonosensitizer	NOUN
admet-2088	205	23	[	[	X
admet-2088	205	24	83	83	NUM
admet-2088	205	25	]	]	PUNCT
admet-2088	205	26	.	.	PUNCT
admet-2088	206	1	advanced	advanced	ADJ
admet-2088	206	2	melanoma	melanoma	NOUN
admet-2088	206	3	patients	patient	NOUN
admet-2088	206	4	or	or	CCONJ
admet-2088	206	5	triple	triple	ADJ
admet-2088	206	6	wild	wild	ADJ
admet-2088	206	7	-	-	PUNCT
admet-2088	206	8	type	type	NOUN
admet-2088	206	9	melanomas	melanomas	NOUN
admet-2088	206	10	,	,	PUNCT
admet-2088	206	11	having	have	VERB
admet-2088	206	12	genotypes	genotype	NOUN
admet-2088	206	13	without	without	ADP
admet-2088	206	14	mutations	mutation	NOUN
admet-2088	206	15	in	in	ADP
admet-2088	206	16	the	the	DET
admet-2088	206	17	braf	braf	NOUN
admet-2088	206	18	,	,	PUNCT
admet-2088	206	19	nfi	nfi	PROPN
admet-2088	206	20	or	or	CCONJ
admet-2088	206	21	nras	nras	PROPN
admet-2088	206	22	genes	gene	NOUN
admet-2088	206	23	,	,	PUNCT
admet-2088	206	24	are	be	AUX
admet-2088	206	25	completely	completely	ADV
admet-2088	206	26	neglected	neglect	VERB
admet-2088	206	27	without	without	ADP
admet-2088	206	28	effective	effective	ADJ
admet-2088	206	29	and	and	CCONJ
admet-2088	206	30	safe	safe	ADJ
admet-2088	206	31	therapeutic	therapeutic	ADJ
admet-2088	206	32	options	option	NOUN
admet-2088	206	33	.	.	PUNCT
admet-2088	207	1	therefore	therefore	ADV
admet-2088	207	2	,	,	PUNCT
admet-2088	207	3	gonçalves	gonçalves	PROPN
admet-2088	207	4	et	et	NOUN
admet-2088	207	5	al	al	PROPN
admet-2088	207	6	.	.	PUNCT
admet-2088	208	1	[	[	X
admet-2088	208	2	9	9	NUM
admet-2088	208	3	]	]	PUNCT
admet-2088	208	4	developed	developed	ADJ
admet-2088	208	5	gum	gum	NOUN
admet-2088	208	6	arabic	arabic	ADV
admet-2088	208	7	-	-	PUNCT
admet-2088	208	8	functionalized	functionalize	VERB
admet-2088	208	9	gold	gold	NOUN
admet-2088	208	10	nanorods	nanorod	NOUN
admet-2088	208	11	(	(	PUNCT
admet-2088	208	12	ga	ga	NOUN
admet-2088	208	13	-	-	PUNCT
admet-2088	208	14	aunrs	aunrs	NOUN
admet-2088	208	15	)	)	PUNCT
admet-2088	208	16	,	,	PUNCT
admet-2088	208	17	where	where	SCONJ
admet-2088	208	18	gum	gum	NOUN
admet-2088	208	19	arabic	arabic	NOUN
admet-2088	208	20	improved	improve	VERB
admet-2088	208	21	biocompatibility	biocompatibility	NOUN
admet-2088	208	22	and	and	CCONJ
admet-2088	208	23	successfully	successfully	ADV
admet-2088	208	24	stabilized	stabilize	VERB
admet-2088	208	25	the	the	DET
admet-2088	208	26	nanorods	nanorod	NOUN
admet-2088	208	27	in	in	ADP
admet-2088	208	28	the	the	DET
admet-2088	208	29	biological	biological	ADJ
admet-2088	208	30	environment	environment	NOUN
admet-2088	208	31	.	.	PUNCT
admet-2088	209	1	these	these	DET
admet-2088	209	2	ga	ga	NOUN
admet-2088	209	3	-	-	PUNCT
admet-2088	209	4	aunrs	aunrs	NOUN
admet-2088	209	5	exceptionally	exceptionally	ADV
admet-2088	209	6	reduced	reduce	VERB
admet-2088	209	7	primary	primary	ADJ
admet-2088	209	8	tumour	tumour	NOUN
admet-2088	209	9	growth	growth	NOUN
admet-2088	209	10	by	by	ADP
admet-2088	209	11	45	45	NUM
admet-2088	209	12	%	%	NOUN
admet-2088	209	13	when	when	SCONJ
admet-2088	209	14	tested	test	VERB
admet-2088	209	15	in	in	ADP
admet-2088	209	16	triple	triple	ADJ
admet-2088	209	17	wild	wild	ADJ
admet-2088	209	18	-	-	PUNCT
admet-2088	209	19	type	type	NOUN
admet-2088	209	20	melanoma	melanoma	NOUN
admet-2088	209	21	induced	induce	VERB
admet-2088	209	22	in	in	ADP
admet-2088	209	23	mice	mouse	NOUN
admet-2088	209	24	.	.	PUNCT
admet-2088	210	1	this	this	DET
admet-2088	210	2	result	result	NOUN
admet-2088	210	3	is	be	AUX
admet-2088	210	4	attributed	attribute	VERB
admet-2088	210	5	to	to	ADP
admet-2088	210	6	the	the	DET
admet-2088	210	7	composite	composite	ADJ
admet-2088	210	8	structure	structure	NOUN
admet-2088	210	9	capacity	capacity	NOUN
admet-2088	210	10	of	of	ADP
admet-2088	210	11	reducing	reduce	VERB
admet-2088	210	12	melanoma	melanoma	NOUN
admet-2088	210	13	cells	cell	NOUN
admet-2088	210	14	'	'	PART
admet-2088	210	15	ability	ability	NOUN
admet-2088	210	16	to	to	PART
admet-2088	210	17	invade	invade	VERB
admet-2088	210	18	the	the	DET
admet-2088	210	19	extracellular	extracellular	ADJ
admet-2088	210	20	matrix	matrix	NOUN
admet-2088	210	21	and	and	CCONJ
admet-2088	210	22	grow	grow	VERB
admet-2088	210	23	into	into	ADP
admet-2088	210	24	colonies	colony	NOUN
admet-2088	210	25	,	,	PUNCT
admet-2088	210	26	thus	thus	ADV
admet-2088	210	27	,	,	PUNCT
admet-2088	210	28	they	they	PRON
admet-2088	210	29	can	can	AUX
admet-2088	210	30	be	be	AUX
admet-2088	210	31	safely	safely	ADV
admet-2088	210	32	and	and	CCONJ
admet-2088	210	33	effectively	effectively	ADV
admet-2088	210	34	used	use	VERB
admet-2088	210	35	against	against	ADP
admet-2088	210	36	subcutaneous	subcutaneous	ADJ
admet-2088	210	37	tumours	tumour	NOUN
admet-2088	210	38	and	and	CCONJ
admet-2088	210	39	metastasis	metastasis	NOUN
admet-2088	210	40	.	.	PUNCT
admet-2088	211	1	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	211	2	m.	m.	NOUN
admet-2088	211	3	kulkarni	kulkarni	PROPN
admet-2088	211	4	et	et	PROPN
admet-2088	211	5	al	al	PROPN
admet-2088	211	6	.	.	PROPN
admet-2088	211	7	admet	admet	PROPN
admet-2088	211	8	&	&	CCONJ
admet-2088	211	9	dmpk	dmpk	PROPN
admet-2088	211	10	12(1	12(1	PROPN
admet-2088	211	11	)	)	PUNCT
admet-2088	211	12	(	(	PUNCT
admet-2088	211	13	2024	2024	NUM
admet-2088	211	14	)	)	PUNCT
admet-2088	211	15	107	107	NUM
admet-2088	211	16	-	-	SYM
admet-2088	211	17	150	150	NUM
admet-2088	211	18	116	116	NUM
admet-2088	211	19	locally	locally	ADV
admet-2088	211	20	advanced	advanced	ADJ
admet-2088	211	21	melanoma	melanoma	NOUN
admet-2088	211	22	has	have	AUX
admet-2088	211	23	decreased	decrease	VERB
admet-2088	211	24	10	10	NUM
admet-2088	211	25	-	-	PUNCT
admet-2088	211	26	year	year	NOUN
admet-2088	211	27	survival	survival	NOUN
admet-2088	211	28	rate	rate	NOUN
admet-2088	211	29	from	from	ADP
admet-2088	211	30	24	24	NUM
admet-2088	211	31	to	to	ADP
admet-2088	211	32	68	68	NUM
admet-2088	211	33	%	%	NOUN
admet-2088	211	34	due	due	ADP
admet-2088	211	35	to	to	ADP
admet-2088	211	36	drug	drug	NOUN
admet-2088	211	37	resistance	resistance	NOUN
admet-2088	211	38	and	and	CCONJ
admet-2088	211	39	inefficient	inefficient	ADJ
admet-2088	211	40	targeted	target	VERB
admet-2088	211	41	chemotherapeutic	chemotherapeutic	ADJ
admet-2088	211	42	agent	agent	NOUN
admet-2088	211	43	delivery	delivery	NOUN
admet-2088	211	44	.	.	PUNCT
admet-2088	212	1	to	to	PART
admet-2088	212	2	circumvent	circumvent	VERB
admet-2088	212	3	the	the	DET
admet-2088	212	4	above	above	ADJ
admet-2088	212	5	problem	problem	NOUN
admet-2088	212	6	,	,	PUNCT
admet-2088	212	7	banstola	banstola	PROPN
admet-2088	212	8	et	et	PROPN
admet-2088	212	9	al	al	PROPN
admet-2088	212	10	.	.	PUNCT
admet-2088	213	1	[	[	X
admet-2088	213	2	84	84	NUM
admet-2088	213	3	]	]	PUNCT
admet-2088	213	4	fabricated	fabricate	VERB
admet-2088	213	5	anti	anti	ADJ
admet-2088	213	6	-	-	ADJ
admet-2088	213	7	pd	pd	ADJ
admet-2088	213	8	-	-	PUNCT
admet-2088	213	9	l1	l1	NOUN
admet-2088	213	10	conjugated	conjugate	VERB
admet-2088	213	11	and	and	CCONJ
admet-2088	213	12	doxorubicin	doxorubicin	PROPN
admet-2088	213	13	-	-	PUNCT
admet-2088	213	14	loaded	load	VERB
admet-2088	213	15	gold	gold	NOUN
admet-2088	213	16	nanoshells	nanoshell	NOUN
admet-2088	213	17	(	(	PUNCT
admet-2088	213	18	t	t	NOUN
admet-2088	213	19	-	-	PUNCT
admet-2088	213	20	hgns	hgn	NOUN
admet-2088	213	21	-	-	PUNCT
admet-2088	213	22	dox	dox	NOUN
admet-2088	213	23	)	)	PUNCT
admet-2088	213	24	.	.	PUNCT
admet-2088	214	1	a	a	DET
admet-2088	214	2	significantly	significantly	ADV
admet-2088	214	3	higher	high	ADJ
admet-2088	214	4	level	level	NOUN
admet-2088	214	5	of	of	ADP
admet-2088	214	6	pd	pd	PROPN
admet-2088	214	7	-	-	PROPN
admet-2088	214	8	l1	l1	PROPN
admet-2088	214	9	was	be	AUX
admet-2088	214	10	expressed	express	VERB
admet-2088	214	11	in	in	ADP
admet-2088	214	12	the	the	DET
admet-2088	214	13	patient	patient	NOUN
admet-2088	214	14	who	who	PRON
admet-2088	214	15	died	die	VERB
admet-2088	214	16	of	of	ADP
admet-2088	214	17	locally	locally	ADV
admet-2088	214	18	advanced	advanced	ADJ
admet-2088	214	19	melanoma	melanoma	NOUN
admet-2088	214	20	.	.	PUNCT
admet-2088	215	1	these	these	DET
admet-2088	215	2	nanosystems	nanosystem	NOUN
admet-2088	215	3	showed	show	VERB
admet-2088	215	4	exceptional	exceptional	ADJ
admet-2088	215	5	in	in	ADP
admet-2088	215	6	vitro	vitro	X
admet-2088	215	7	and	and	CCONJ
admet-2088	215	8	in	in	ADP
admet-2088	215	9	vivo	vivo	ADJ
admet-2088	215	10	inhibition	inhibition	NOUN
admet-2088	215	11	of	of	ADP
admet-2088	215	12	the	the	DET
admet-2088	215	13	melanoma	melanoma	NOUN
admet-2088	215	14	cancer	cancer	NOUN
admet-2088	215	15	model	model	NOUN
admet-2088	215	16	.	.	PUNCT
admet-2088	216	1	when	when	SCONJ
admet-2088	216	2	conjugated	conjugate	VERB
admet-2088	216	3	with	with	ADP
admet-2088	216	4	an	an	DET
admet-2088	216	5	antibody	antibody	NOUN
admet-2088	216	6	and	and	CCONJ
admet-2088	216	7	short	short	ADJ
admet-2088	216	8	chain	chain	NOUN
admet-2088	216	9	of	of	ADP
admet-2088	216	10	peg	peg	NOUN
admet-2088	216	11	on	on	ADP
admet-2088	216	12	the	the	DET
admet-2088	216	13	surface	surface	NOUN
admet-2088	216	14	of	of	ADP
admet-2088	216	15	t	t	PROPN
admet-2088	216	16	-	-	PUNCT
admet-2088	216	17	hgns	hgn	NOUN
admet-2088	216	18	-	-	PUNCT
admet-2088	216	19	dox	dox	NOUN
admet-2088	216	20	,	,	PUNCT
admet-2088	216	21	it	it	PRON
admet-2088	216	22	demonstrated	demonstrate	VERB
admet-2088	216	23	improved	improved	ADJ
admet-2088	216	24	precise	precise	ADJ
admet-2088	216	25	targeting	target	VERB
admet-2088	216	26	and	and	CCONJ
admet-2088	216	27	localized	localize	VERB
admet-2088	216	28	doxorubicin	doxorubicin	PROPN
admet-2088	216	29	delivery	delivery	NOUN
admet-2088	216	30	to	to	ADP
admet-2088	216	31	melanoma	melanoma	NOUN
admet-2088	216	32	cells	cell	NOUN
admet-2088	216	33	.	.	PUNCT
admet-2088	217	1	thus	thus	ADV
admet-2088	217	2	,	,	PUNCT
admet-2088	217	3	it	it	PRON
admet-2088	217	4	can	can	AUX
admet-2088	217	5	be	be	AUX
admet-2088	217	6	concluded	conclude	VERB
admet-2088	217	7	that	that	SCONJ
admet-2088	217	8	following	follow	VERB
admet-2088	217	9	intratumoral	intratumoral	ADJ
admet-2088	217	10	administration	administration	NOUN
admet-2088	217	11	of	of	ADP
admet-2088	217	12	these	these	DET
admet-2088	217	13	nanoformulations	nanoformulation	NOUN
admet-2088	217	14	led	lead	VERB
admet-2088	217	15	to	to	ADP
admet-2088	217	16	their	their	PRON
admet-2088	217	17	maximum	maximum	ADJ
admet-2088	217	18	retention	retention	NOUN
admet-2088	217	19	and	and	CCONJ
admet-2088	217	20	a	a	DET
admet-2088	217	21	considerable	considerable	ADJ
admet-2088	217	22	decrease	decrease	NOUN
admet-2088	217	23	in	in	ADP
admet-2088	217	24	tumour	tumour	ADJ
admet-2088	217	25	growth	growth	NOUN
admet-2088	217	26	due	due	ADP
admet-2088	217	27	to	to	ADP
admet-2088	217	28	elevated	elevate	VERB
admet-2088	217	29	apoptosis	apoptosis	NOUN
admet-2088	217	30	markers	marker	NOUN
admet-2088	217	31	and	and	CCONJ
admet-2088	217	32	downregulation	downregulation	NOUN
admet-2088	217	33	of	of	ADP
admet-2088	217	34	angiogenesis	angiogenesis	NOUN
admet-2088	217	35	and	and	CCONJ
admet-2088	217	36	proliferative	proliferative	ADJ
admet-2088	217	37	markers	marker	NOUN
admet-2088	217	38	[	[	X
admet-2088	217	39	85	85	NUM
admet-2088	217	40	]	]	PUNCT
admet-2088	217	41	.	.	PUNCT
admet-2088	218	1	a	a	DET
admet-2088	218	2	novel	novel	ADJ
admet-2088	218	3	and	and	CCONJ
admet-2088	218	4	versatile	versatile	ADJ
admet-2088	218	5	theranostic	theranostic	ADJ
admet-2088	218	6	nanoprobe	nanoprobe	NOUN
admet-2088	218	7	comprised	comprise	VERB
admet-2088	218	8	of	of	ADP
admet-2088	218	9	gold	gold	NOUN
admet-2088	218	10	nanocages	nanocage	NOUN
admet-2088	218	11	labelled	label	VERB
admet-2088	218	12	with	with	ADP
admet-2088	218	13	4	4	NUM
admet-2088	218	14	-	-	PUNCT
admet-2088	218	15	mercapto	mercapto	NOUN
admet-2088	218	16	benzoic	benzoic	NOUN
admet-2088	218	17	acid	acid	NOUN
admet-2088	218	18	(	(	PUNCT
admet-2088	218	19	p	p	NOUN
admet-2088	218	20	-	-	PUNCT
admet-2088	218	21	mba	mba	NOUN
admet-2088	218	22	)	)	PUNCT
admet-2088	218	23	,	,	PUNCT
admet-2088	218	24	followed	follow	VERB
admet-2088	218	25	by	by	ADP
admet-2088	218	26	coating	coat	VERB
admet-2088	218	27	with	with	ADP
admet-2088	218	28	liposomal	liposomal	ADJ
admet-2088	218	29	layer	layer	NOUN
admet-2088	218	30	and	and	CCONJ
admet-2088	218	31	then	then	ADV
admet-2088	218	32	conjugated	conjugate	VERB
admet-2088	218	33	with	with	ADP
admet-2088	218	34	anti	anti	ADJ
admet-2088	218	35	-	-	ADJ
admet-2088	218	36	muc18	muc18	ADJ
admet-2088	218	37	single	single	ADJ
admet-2088	218	38	chain	chain	NOUN
admet-2088	218	39	antibody	antibody	NOUN
admet-2088	218	40	(	(	PUNCT
admet-2088	218	41	scfy	scfy	NOUN
admet-2088	218	42	)	)	PUNCT
admet-2088	218	43	was	be	AUX
admet-2088	218	44	developed	develop	VERB
admet-2088	218	45	for	for	ADP
admet-2088	218	46	melanoma	melanoma	ADJ
admet-2088	218	47	diagnosis	diagnosis	NOUN
admet-2088	218	48	and	and	CCONJ
admet-2088	218	49	selective	selective	ADJ
admet-2088	218	50	treatment	treatment	NOUN
admet-2088	218	51	of	of	ADP
admet-2088	218	52	melanoma	melanoma	NOUN
admet-2088	218	53	cancer	cancer	NOUN
admet-2088	218	54	.	.	PUNCT
admet-2088	219	1	the	the	DET
admet-2088	219	2	nanoprobe	nanoprobe	NOUN
admet-2088	219	3	(	(	PUNCT
admet-2088	219	4	p	p	NOUN
admet-2088	219	5	-	-	PUNCT
admet-2088	219	6	auncs@scfv	auncs@scfv	NOUN
admet-2088	219	7	-	-	PUNCT
admet-2088	219	8	lip	lip	NOUN
admet-2088	219	9	)	)	PUNCT
admet-2088	219	10	showed	show	VERB
admet-2088	219	11	24	24	NUM
admet-2088	219	12	-	-	ADJ
admet-2088	219	13	fold	fold	ADJ
admet-2088	219	14	cellular	cellular	ADJ
admet-2088	219	15	uptake	uptake	NOUN
admet-2088	219	16	by	by	ADP
admet-2088	219	17	the	the	DET
admet-2088	219	18	a375	a375	PROPN
admet-2088	219	19	cell	cell	NOUN
admet-2088	219	20	line	line	NOUN
admet-2088	219	21	than	than	ADP
admet-2088	219	22	that	that	PRON
admet-2088	219	23	of	of	ADP
admet-2088	219	24	the	the	DET
admet-2088	219	25	skbr3	skbr3	PROPN
admet-2088	219	26	cell	cell	NOUN
admet-2088	219	27	line	line	NOUN
admet-2088	219	28	.	.	PUNCT
admet-2088	220	1	this	this	DET
admet-2088	220	2	nanoprobe	nanoprobe	NOUN
admet-2088	220	3	specifically	specifically	ADV
admet-2088	220	4	identified	identify	VERB
admet-2088	220	5	a375	a375	PROPN
admet-2088	220	6	cells	cell	NOUN
admet-2088	220	7	through	through	ADP
admet-2088	220	8	surface	surface	NOUN
admet-2088	220	9	-	-	PUNCT
admet-2088	220	10	enhanced	enhance	VERB
admet-2088	220	11	raman	raman	NOUN
admet-2088	220	12	spectroscopy	spectroscopy	NOUN
admet-2088	220	13	and	and	CCONJ
admet-2088	220	14	selectively	selectively	ADV
admet-2088	220	15	killed	kill	VERB
admet-2088	220	16	a375	a375	PROPN
admet-2088	220	17	cells	cell	NOUN
admet-2088	220	18	through	through	ADP
admet-2088	220	19	the	the	DET
admet-2088	220	20	ptt	ptt	PROPN
admet-2088	220	21	principle	principle	NOUN
admet-2088	220	22	.	.	PUNCT
admet-2088	221	1	thus	thus	ADV
admet-2088	221	2	,	,	PUNCT
admet-2088	221	3	the	the	DET
admet-2088	221	4	nanoprobe	nanoprobe	NOUN
admet-2088	221	5	would	would	AUX
admet-2088	221	6	act	act	VERB
admet-2088	221	7	as	as	ADP
admet-2088	221	8	a	a	DET
admet-2088	221	9	great	great	ADJ
admet-2088	221	10	tool	tool	NOUN
admet-2088	221	11	for	for	ADP
admet-2088	221	12	in	in	ADP
admet-2088	221	13	vivo	vivo	ADJ
admet-2088	221	14	tumour	tumour	NOUN
admet-2088	221	15	site	site	NOUN
admet-2088	221	16	tracing	tracing	NOUN
admet-2088	221	17	,	,	PUNCT
admet-2088	221	18	biodistribution	biodistribution	NOUN
admet-2088	221	19	study	study	NOUN
admet-2088	221	20	and	and	CCONJ
admet-2088	221	21	targeted	target	VERB
admet-2088	221	22	treatment	treatment	NOUN
admet-2088	221	23	of	of	ADP
admet-2088	221	24	cancer	cancer	NOUN
admet-2088	221	25	by	by	ADP
admet-2088	221	26	combining	combine	VERB
admet-2088	221	27	chemotherapy	chemotherapy	NOUN
admet-2088	221	28	and	and	CCONJ
admet-2088	221	29	immunotherapy	immunotherapy	NOUN
admet-2088	221	30	[	[	X
admet-2088	221	31	86	86	NUM
admet-2088	221	32	]	]	PUNCT
admet-2088	221	33	.	.	PUNCT
admet-2088	222	1	in	in	ADP
admet-2088	222	2	one	one	NUM
admet-2088	222	3	investigation	investigation	NOUN
admet-2088	222	4	,	,	PUNCT
admet-2088	222	5	gold	gold	PROPN
admet-2088	222	6	nps	nps	PROPN
admet-2088	222	7	coated	coat	VERB
admet-2088	222	8	with	with	ADP
admet-2088	222	9	hyaluronic	hyaluronic	ADJ
admet-2088	222	10	acid	acid	NOUN
admet-2088	222	11	(	(	PUNCT
admet-2088	222	12	ha	ha	INTJ
admet-2088	222	13	)	)	PUNCT
admet-2088	222	14	and	and	CCONJ
admet-2088	222	15	oleic	oleic	VERB
admet-2088	222	16	acid	acid	PROPN
admet-2088	222	17	were	be	AUX
admet-2088	222	18	developed	develop	VERB
admet-2088	222	19	and	and	CCONJ
admet-2088	222	20	combined	combine	VERB
admet-2088	222	21	with	with	ADP
admet-2088	222	22	ptt	ptt	NOUN
admet-2088	222	23	for	for	ADP
admet-2088	222	24	the	the	DET
admet-2088	222	25	synergistic	synergistic	ADJ
admet-2088	222	26	treatment	treatment	NOUN
admet-2088	222	27	of	of	ADP
admet-2088	222	28	melanoma	melanoma	NOUN
admet-2088	222	29	.	.	PUNCT
admet-2088	223	1	when	when	SCONJ
admet-2088	223	2	the	the	DET
admet-2088	223	3	biocompatible	biocompatible	ADJ
admet-2088	223	4	gold	gold	PROPN
admet-2088	223	5	nps	nps	PROPN
admet-2088	223	6	with	with	ADP
admet-2088	223	7	a	a	DET
admet-2088	223	8	mean	mean	ADJ
admet-2088	223	9	size	size	NOUN
admet-2088	223	10	of	of	ADP
admet-2088	223	11	297	297	NUM
admet-2088	223	12	nm	nm	NOUN
admet-2088	223	13	were	be	AUX
admet-2088	223	14	used	use	VERB
admet-2088	223	15	alone	alone	ADV
admet-2088	223	16	,	,	PUNCT
admet-2088	223	17	they	they	PRON
admet-2088	223	18	showed	show	VERB
admet-2088	223	19	no	no	DET
admet-2088	223	20	cytotoxic	cytotoxic	ADJ
admet-2088	223	21	effect	effect	NOUN
admet-2088	223	22	on	on	ADP
admet-2088	223	23	yeast	yeast	NOUN
admet-2088	223	24	and	and	CCONJ
admet-2088	223	25	tested	test	VERB
admet-2088	223	26	cell	cell	NOUN
admet-2088	223	27	lines	line	NOUN
admet-2088	223	28	.	.	PUNCT
admet-2088	224	1	however	however	ADV
admet-2088	224	2	,	,	PUNCT
admet-2088	224	3	gold	gold	PROPN
admet-2088	224	4	np	np	PROPN
admet-2088	224	5	administration	administration	NOUN
admet-2088	224	6	followed	follow	VERB
admet-2088	224	7	by	by	ADP
admet-2088	224	8	laser	laser	NOUN
admet-2088	224	9	irradiation	irradiation	NOUN
admet-2088	224	10	(	(	PUNCT
admet-2088	224	11	750–1400	750–1400	NUM
admet-2088	224	12	nm	nm	NOUN
admet-2088	224	13	)	)	PUNCT
admet-2088	224	14	showed	show	VERB
admet-2088	224	15	a	a	DET
admet-2088	224	16	reduction	reduction	NOUN
admet-2088	224	17	of	of	ADP
admet-2088	224	18	20	20	NUM
admet-2088	224	19	%	%	NOUN
admet-2088	224	20	in	in	ADP
admet-2088	224	21	melanoma	melanoma	NOUN
admet-2088	224	22	cell	cell	NOUN
admet-2088	224	23	line	line	NOUN
admet-2088	224	24	(	(	PUNCT
admet-2088	224	25	b16f10	b16f10	ADJ
admet-2088	224	26	)	)	PUNCT
admet-2088	224	27	viability	viability	NOUN
admet-2088	224	28	.	.	PUNCT
admet-2088	225	1	thus	thus	ADV
admet-2088	225	2	,	,	PUNCT
admet-2088	225	3	this	this	DET
admet-2088	225	4	strategy	strategy	NOUN
admet-2088	225	5	seems	seem	VERB
admet-2088	225	6	to	to	PART
admet-2088	225	7	be	be	AUX
admet-2088	225	8	effective	effective	ADJ
admet-2088	225	9	against	against	ADP
admet-2088	225	10	,	,	PUNCT
admet-2088	225	11	in	in	ADP
admet-2088	225	12	particular	particular	ADJ
admet-2088	225	13	,	,	PUNCT
admet-2088	225	14	against	against	ADP
admet-2088	225	15	non	non	ADJ
admet-2088	225	16	-	-	ADJ
admet-2088	225	17	metastatic	metastatic	ADJ
admet-2088	225	18	melanoma	melanoma	NOUN
admet-2088	225	19	or	or	CCONJ
admet-2088	225	20	other	other	ADJ
admet-2088	225	21	superficial	superficial	ADJ
admet-2088	225	22	tumours	tumour	NOUN
admet-2088	226	1	[	[	X
admet-2088	226	2	87	87	NUM
admet-2088	226	3	]	]	PUNCT
admet-2088	226	4	.	.	PUNCT
admet-2088	227	1	in	in	ADP
admet-2088	227	2	another	another	DET
admet-2088	227	3	investigation	investigation	NOUN
admet-2088	227	4	,	,	PUNCT
admet-2088	227	5	shanei	shanei	PROPN
admet-2088	227	6	et	et	PROPN
admet-2088	227	7	al	al	PROPN
admet-2088	227	8	.	.	PUNCT
admet-2088	228	1	[	[	X
admet-2088	228	2	88	88	NUM
admet-2088	228	3	]	]	PUNCT
admet-2088	228	4	combined	combine	VERB
admet-2088	228	5	gold	gold	PROPN
admet-2088	228	6	nps	nps	PROPN
admet-2088	228	7	conjugated	conjugate	VERB
admet-2088	228	8	folic	folic	NOUN
admet-2088	228	9	acid	acid	NOUN
admet-2088	228	10	(	(	PUNCT
admet-2088	228	11	f	f	X
admet-2088	228	12	-	-	PUNCT
admet-2088	228	13	cys	cys	NOUN
admet-2088	228	14	-	-	PUNCT
admet-2088	228	15	gnps	gnps	NOUN
admet-2088	228	16	)	)	PUNCT
admet-2088	228	17	with	with	ADP
admet-2088	228	18	acoustic	acoustic	ADJ
admet-2088	228	19	cavitation	cavitation	NOUN
admet-2088	228	20	.	.	PUNCT
admet-2088	229	1	the	the	DET
admet-2088	229	2	result	result	NOUN
admet-2088	229	3	showed	show	VERB
admet-2088	229	4	decreased	decrease	VERB
admet-2088	229	5	viability	viability	NOUN
admet-2088	229	6	of	of	ADP
admet-2088	229	7	melanoma	melanoma	NOUN
admet-2088	229	8	cells	cell	NOUN
admet-2088	229	9	at	at	ADP
admet-2088	229	10	higher	high	ADJ
admet-2088	229	11	concentrations	concentration	NOUN
admet-2088	229	12	and	and	CCONJ
admet-2088	229	13	sizes	size	NOUN
admet-2088	229	14	of	of	ADP
admet-2088	229	15	nps	nps	PROPN
admet-2088	229	16	with	with	ADP
admet-2088	229	17	adequate	adequate	ADJ
admet-2088	229	18	irradiation	irradiation	NOUN
admet-2088	229	19	(	(	PUNCT
admet-2088	229	20	frequency	frequency	NOUN
admet-2088	229	21	of	of	ADP
admet-2088	229	22	1	1	NUM
admet-2088	229	23	mhz	mhz	NOUN
admet-2088	229	24	)	)	PUNCT
admet-2088	229	25	.	.	PUNCT
admet-2088	230	1	there	there	PRON
admet-2088	230	2	was	be	VERB
admet-2088	230	3	a	a	DET
admet-2088	230	4	significant	significant	ADJ
admet-2088	230	5	decrease	decrease	NOUN
admet-2088	230	6	in	in	ADP
admet-2088	230	7	side	side	NOUN
admet-2088	230	8	effects	effect	NOUN
admet-2088	230	9	due	due	ADJ
admet-2088	230	10	to	to	ADP
admet-2088	230	11	the	the	DET
admet-2088	230	12	presence	presence	NOUN
admet-2088	230	13	of	of	ADP
admet-2088	230	14	folic	folic	ADJ
admet-2088	230	15	acid	acid	NOUN
admet-2088	230	16	on	on	ADP
admet-2088	230	17	the	the	DET
admet-2088	230	18	surface	surface	NOUN
admet-2088	230	19	of	of	ADP
admet-2088	230	20	nps	nps	PROPN
admet-2088	230	21	,	,	PUNCT
admet-2088	230	22	which	which	PRON
admet-2088	230	23	are	be	AUX
admet-2088	230	24	specifically	specifically	ADV
admet-2088	230	25	bound	bind	VERB
admet-2088	230	26	to	to	PART
admet-2088	230	27	folic	folic	VERB
admet-2088	230	28	acid	acid	NOUN
admet-2088	230	29	receptors	receptor	NOUN
admet-2088	230	30	abundantly	abundantly	ADV
admet-2088	230	31	expressed	express	VERB
admet-2088	230	32	in	in	ADP
admet-2088	230	33	melanoma	melanoma	NOUN
admet-2088	230	34	cells	cell	NOUN
admet-2088	230	35	.	.	PUNCT
admet-2088	231	1	nanocomposite	nanocomposite	PROPN
admet-2088	231	2	comprised	comprise	VERB
admet-2088	231	3	of	of	ADP
admet-2088	231	4	gold	gold	PROPN
admet-2088	231	5	nps	nps	PROPN
admet-2088	231	6	of	of	ADP
admet-2088	231	7	11.53±2.14	11.53±2.14	NUM
admet-2088	231	8	nm	nm	NOUN
admet-2088	231	9	in	in	ADP
admet-2088	231	10	diameter	diameter	NOUN
admet-2088	231	11	and	and	CCONJ
admet-2088	231	12	tio2	tio2	NOUN
admet-2088	231	13	nanorods	nanorod	NOUN
admet-2088	231	14	of	of	ADP
admet-2088	231	15	81.72±29.02	81.72±29.02	NUM
admet-2088	231	16	and	and	CCONJ
admet-2088	231	17	22.38±4.74	22.38±4.74	NUM
admet-2088	231	18	nm	nm	NOUN
admet-2088	231	19	in	in	ADP
admet-2088	231	20	length	length	NOUN
admet-2088	231	21	and	and	CCONJ
admet-2088	231	22	diameter	diameter	NOUN
admet-2088	231	23	,	,	PUNCT
admet-2088	231	24	respectively	respectively	ADV
admet-2088	231	25	,	,	PUNCT
admet-2088	231	26	was	be	AUX
admet-2088	231	27	developed	develop	VERB
admet-2088	231	28	and	and	CCONJ
admet-2088	231	29	combined	combine	VERB
admet-2088	231	30	with	with	ADP
admet-2088	231	31	ptt	ptt	NOUN
admet-2088	231	32	and	and	CCONJ
admet-2088	231	33	sdt	sdt	NOUN
admet-2088	231	34	separately	separately	ADV
admet-2088	231	35	and	and	CCONJ
admet-2088	231	36	in	in	ADP
admet-2088	231	37	combination	combination	NOUN
admet-2088	231	38	for	for	ADP
admet-2088	231	39	the	the	DET
admet-2088	231	40	treatment	treatment	NOUN
admet-2088	231	41	of	of	ADP
admet-2088	231	42	melanoma	melanoma	NOUN
admet-2088	231	43	.	.	PUNCT
admet-2088	232	1	the	the	DET
admet-2088	232	2	au	au	PROPN
admet-2088	232	3	-	-	ADJ
admet-2088	232	4	tio2	tio2	ADJ
admet-2088	232	5	nanocomposite	nanocomposite	NOUN
admet-2088	232	6	was	be	AUX
admet-2088	232	7	found	find	VERB
admet-2088	232	8	to	to	PART
admet-2088	232	9	be	be	AUX
admet-2088	232	10	highly	highly	ADV
admet-2088	232	11	stable	stable	ADJ
admet-2088	232	12	and	and	CCONJ
admet-2088	232	13	biocompatible	biocompatible	ADJ
admet-2088	232	14	and	and	CCONJ
admet-2088	232	15	showed	show	VERB
admet-2088	232	16	excellent	excellent	ADJ
admet-2088	232	17	photothermal	photothermal	ADJ
admet-2088	232	18	conversion	conversion	NOUN
admet-2088	232	19	efficiency	efficiency	NOUN
admet-2088	232	20	.	.	PUNCT
admet-2088	233	1	upon	upon	SCONJ
admet-2088	233	2	exposure	exposure	NOUN
admet-2088	233	3	to	to	ADP
admet-2088	233	4	both	both	DET
admet-2088	233	5	ptt	ptt	NOUN
admet-2088	233	6	(	(	PUNCT
admet-2088	233	7	lasers	laser	NOUN
admet-2088	233	8	at	at	ADP
admet-2088	233	9	808	808	NUM
admet-2088	233	10	and	and	CCONJ
admet-2088	233	11	605	605	NUM
admet-2088	233	12	nm	nm	NOUN
admet-2088	233	13	)	)	PUNCT
admet-2088	233	14	and	and	CCONJ
admet-2088	233	15	ultrasound	ultrasound	VERB
admet-2088	233	16	in	in	ADP
admet-2088	233	17	the	the	DET
admet-2088	233	18	presence	presence	NOUN
admet-2088	233	19	of	of	ADP
admet-2088	233	20	100	100	NUM
admet-2088	233	21	and	and	CCONJ
admet-2088	233	22	250	250	NUM
admet-2088	233	23	μg	μg	PROPN
admet-2088	233	24	ml-1	ml-1	CCONJ
admet-2088	233	25	au	au	PROPN
admet-2088	233	26	-	-	NOUN
admet-2088	233	27	tio2	tio2	NOUN
admet-2088	233	28	,	,	PUNCT
admet-2088	233	29	intensive	intensive	ADJ
admet-2088	233	30	apoptosis	apoptosis	NOUN
admet-2088	233	31	and	and	CCONJ
admet-2088	233	32	total	total	ADJ
admet-2088	233	33	ablation	ablation	NOUN
admet-2088	233	34	happened	happen	VERB
admet-2088	233	35	in	in	ADP
admet-2088	233	36	melanoma	melanoma	NOUN
admet-2088	233	37	cell	cell	NOUN
admet-2088	233	38	line	line	NOUN
admet-2088	233	39	c540	c540	PROPN
admet-2088	233	40	,	,	PUNCT
admet-2088	233	41	resulting	result	VERB
admet-2088	233	42	in	in	ADP
admet-2088	233	43	the	the	DET
admet-2088	233	44	reduction	reduction	NOUN
admet-2088	233	45	of	of	ADP
admet-2088	233	46	cell	cell	NOUN
admet-2088	233	47	viability	viability	NOUN
admet-2088	233	48	to	to	ADP
admet-2088	233	49	less	less	ADJ
admet-2088	233	50	than	than	ADP
admet-2088	233	51	1	1	NUM
admet-2088	233	52	%	%	NOUN
admet-2088	233	53	[	[	X
admet-2088	233	54	89	89	NUM
admet-2088	233	55	]	]	PUNCT
admet-2088	233	56	.	.	PUNCT
admet-2088	234	1	similarly	similarly	ADV
admet-2088	234	2	,	,	PUNCT
admet-2088	234	3	soratijahromi	soratijahromi	VERB
admet-2088	234	4	et	et	PROPN
admet-2088	234	5	al	al	PROPN
admet-2088	234	6	.	.	PUNCT
admet-2088	235	1	[	[	X
admet-2088	235	2	90	90	NUM
admet-2088	235	3	]	]	PUNCT
admet-2088	235	4	developed	develop	VERB
admet-2088	235	5	a	a	DET
admet-2088	235	6	nanocomposite	nanocomposite	NOUN
admet-2088	235	7	of	of	ADP
admet-2088	235	8	gold	gold	PROPN
admet-2088	235	9	nps	nps	PROPN
admet-2088	235	10	of	of	ADP
admet-2088	235	11	125±66	125±66	NUM
admet-2088	235	12	nm	nm	NOUN
admet-2088	235	13	in	in	ADP
admet-2088	235	14	diameter	diameter	NOUN
admet-2088	235	15	and	and	CCONJ
admet-2088	235	16	manganese	manganese	ADJ
admet-2088	235	17	dioxide	dioxide	NOUN
admet-2088	235	18	nanorods	nanorod	NOUN
admet-2088	235	19	of	of	ADP
admet-2088	235	20	77±30	77±30	NUM
admet-2088	235	21	nm	nm	NOUN
admet-2088	235	22	in	in	ADP
admet-2088	235	23	diameter	diameter	NOUN
admet-2088	235	24	and	and	CCONJ
admet-2088	235	25	up	up	ADP
admet-2088	235	26	to	to	PART
admet-2088	235	27	2	2	NUM
admet-2088	235	28	μm	μm	NOUN
admet-2088	235	29	length	length	NOUN
admet-2088	235	30	as	as	ADP
admet-2088	235	31	novel	novel	ADJ
admet-2088	235	32	photosensitizer	photosensitizer	NOUN
admet-2088	235	33	/	/	SYM
admet-2088	235	34	sonosensitizer	sonosensitizer	NOUN
admet-2088	235	35	for	for	ADP
admet-2088	235	36	ptt	ptt	NOUN
admet-2088	235	37	and	and	CCONJ
admet-2088	235	38	sdt	sdt	PROPN
admet-2088	235	39	in	in	ADP
admet-2088	235	40	the	the	DET
admet-2088	235	41	treatment	treatment	NOUN
admet-2088	235	42	of	of	ADP
admet-2088	235	43	melanoma	melanoma	NOUN
admet-2088	235	44	.	.	PUNCT
admet-2088	236	1	cytotoxicity	cytotoxicity	NOUN
admet-2088	236	2	of	of	ADP
admet-2088	236	3	au	au	PROPN
admet-2088	236	4	-	-	ADJ
admet-2088	236	5	mno2	mno2	ADJ
admet-2088	236	6	nanocomposite	nanocomposite	NOUN
admet-2088	236	7	toward	toward	ADP
admet-2088	236	8	c540	c540	PROPN
admet-2088	236	9	cell	cell	NOUN
admet-2088	236	10	lines	line	NOUN
admet-2088	236	11	was	be	AUX
admet-2088	236	12	found	find	VERB
admet-2088	236	13	to	to	PART
admet-2088	236	14	be	be	AUX
admet-2088	236	15	increased	increase	VERB
admet-2088	236	16	in	in	ADP
admet-2088	236	17	a	a	DET
admet-2088	236	18	dose	dose	NOUN
admet-2088	236	19	-	-	PUNCT
admet-2088	236	20	dependent	dependent	ADJ
admet-2088	236	21	manner	manner	NOUN
admet-2088	236	22	.	.	PUNCT
admet-2088	237	1	intramural	intramural	ADJ
admet-2088	237	2	administration	administration	NOUN
admet-2088	237	3	of	of	ADP
admet-2088	237	4	a	a	DET
admet-2088	237	5	low	low	ADJ
admet-2088	237	6	dose	dose	NOUN
admet-2088	237	7	of	of	ADP
admet-2088	237	8	the	the	DET
admet-2088	237	9	nanocomposite	nanocomposite	NOUN
admet-2088	237	10	in	in	ADP
admet-2088	237	11	the	the	DET
admet-2088	237	12	melanoma	melanoma	NOUN
admet-2088	237	13	-	-	PUNCT
admet-2088	237	14	induced	induce	VERB
admet-2088	237	15	animal	animal	NOUN
admet-2088	237	16	,	,	PUNCT
admet-2088	237	17	followed	follow	VERB
admet-2088	237	18	by	by	ADP
admet-2088	237	19	laser	laser	NOUN
admet-2088	237	20	and	and	CCONJ
admet-2088	237	21	ultrasound	ultrasound	ADJ
admet-2088	237	22	radiation	radiation	NOUN
admet-2088	237	23	,	,	PUNCT
admet-2088	237	24	resulted	result	VERB
admet-2088	237	25	in	in	ADP
admet-2088	237	26	necrosis	necrosis	NOUN
admet-2088	237	27	of	of	ADP
admet-2088	237	28	the	the	DET
admet-2088	237	29	melanoma	melanoma	NOUN
admet-2088	237	30	tissues	tissue	NOUN
admet-2088	237	31	.	.	PUNCT
admet-2088	238	1	silver	silver	ADJ
admet-2088	238	2	nanoparticles	nanoparticle	NOUN
admet-2088	238	3	silver	silver	PROPN
admet-2088	238	4	nps	nps	PROPN
admet-2088	238	5	are	be	AUX
admet-2088	238	6	one	one	NUM
admet-2088	238	7	of	of	ADP
admet-2088	238	8	the	the	DET
admet-2088	238	9	most	most	ADV
admet-2088	238	10	vital	vital	ADJ
admet-2088	238	11	nms	nms	NOUN
admet-2088	238	12	among	among	ADP
admet-2088	238	13	several	several	ADJ
admet-2088	238	14	nps	nps	PROPN
admet-2088	238	15	that	that	PRON
admet-2088	238	16	play	play	VERB
admet-2088	238	17	an	an	DET
admet-2088	238	18	important	important	ADJ
admet-2088	238	19	role	role	NOUN
admet-2088	238	20	in	in	ADP
admet-2088	238	21	the	the	DET
admet-2088	238	22	treatment	treatment	NOUN
admet-2088	238	23	of	of	ADP
admet-2088	238	24	cancer	cancer	NOUN
admet-2088	238	25	.	.	PUNCT
admet-2088	239	1	this	this	PRON
admet-2088	239	2	is	be	AUX
admet-2088	239	3	because	because	SCONJ
admet-2088	239	4	of	of	ADP
admet-2088	239	5	their	their	PRON
admet-2088	239	6	extensive	extensive	ADJ
admet-2088	239	7	reactivity	reactivity	NOUN
admet-2088	239	8	,	,	PUNCT
admet-2088	239	9	reduced	reduce	VERB
admet-2088	239	10	size	size	NOUN
admet-2088	239	11	and	and	CCONJ
admet-2088	239	12	spherical	spherical	ADJ
admet-2088	239	13	shape	shape	NOUN
admet-2088	239	14	[	[	X
admet-2088	239	15	91	91	NUM
admet-2088	239	16	]	]	PUNCT
admet-2088	239	17	.	.	PUNCT
admet-2088	240	1	these	these	DET
admet-2088	240	2	properties	property	NOUN
admet-2088	240	3	admet	admet	VERB
admet-2088	240	4	&	&	CCONJ
admet-2088	240	5	dmpk	dmpk	PROPN
admet-2088	240	6	12(1	12(1	PROPN
admet-2088	240	7	)	)	PUNCT
admet-2088	240	8	(	(	PUNCT
admet-2088	240	9	2024	2024	NUM
admet-2088	240	10	)	)	PUNCT
admet-2088	240	11	107	107	NUM
admet-2088	240	12	-	-	SYM
admet-2088	240	13	150	150	NUM
admet-2088	240	14	nanomaterial	nanomaterial	NOUN
admet-2088	240	15	-	-	PUNCT
admet-2088	240	16	based	base	VERB
admet-2088	240	17	drug	drug	NOUN
admet-2088	240	18	delivery	delivery	NOUN
admet-2088	240	19	systems	system	NOUN
admet-2088	240	20	for	for	ADP
admet-2088	240	21	melanoma	melanoma	NOUN
admet-2088	240	22	therapy	therapy	NOUN
admet-2088	240	23	doi	doi	NOUN
admet-2088	240	24	:	:	PUNCT
admet-2088	240	25	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	240	26	117	117	NUM
admet-2088	240	27	enhance	enhance	VERB
admet-2088	240	28	the	the	DET
admet-2088	240	29	bioavailability	bioavailability	NOUN
admet-2088	240	30	of	of	ADP
admet-2088	240	31	therapeutic	therapeutic	ADJ
admet-2088	240	32	molecules	molecule	NOUN
admet-2088	240	33	after	after	ADP
admet-2088	240	34	both	both	CCONJ
admet-2088	240	35	systemic	systemic	ADJ
admet-2088	240	36	and	and	CCONJ
admet-2088	240	37	local	local	ADJ
admet-2088	240	38	administration	administration	NOUN
admet-2088	240	39	through	through	ADP
admet-2088	240	40	penetration	penetration	NOUN
admet-2088	240	41	across	across	ADP
admet-2088	240	42	biological	biological	ADJ
admet-2088	240	43	membranes	membrane	NOUN
admet-2088	240	44	,	,	PUNCT
admet-2088	240	45	distribution	distribution	NOUN
admet-2088	240	46	,	,	PUNCT
admet-2088	240	47	and	and	CCONJ
admet-2088	240	48	cellular	cellular	ADJ
admet-2088	240	49	uptake	uptake	NOUN
admet-2088	240	50	.	.	PUNCT
admet-2088	241	1	silver	silver	PROPN
admet-2088	241	2	nps	nps	PROPN
admet-2088	241	3	acts	act	VERB
admet-2088	241	4	by	by	ADP
admet-2088	241	5	various	various	ADJ
admet-2088	241	6	mechanism	mechanism	NOUN
admet-2088	241	7	against	against	ADP
admet-2088	241	8	cancer	cancer	NOUN
admet-2088	241	9	tissues	tissue	NOUN
admet-2088	241	10	,	,	PUNCT
admet-2088	241	11	including	include	VERB
admet-2088	241	12	induction	induction	NOUN
admet-2088	241	13	of	of	ADP
admet-2088	241	14	apoptosis	apoptosis	NOUN
admet-2088	241	15	,	,	PUNCT
admet-2088	241	16	metabolic	metabolic	NOUN
admet-2088	241	17	changes	change	NOUN
admet-2088	241	18	,	,	PUNCT
admet-2088	241	19	increasing	increase	VERB
admet-2088	241	20	oxidative	oxidative	ADJ
admet-2088	241	21	stress	stress	NOUN
admet-2088	241	22	,	,	PUNCT
admet-2088	241	23	affecting	affect	VERB
admet-2088	241	24	membrane	membrane	NOUN
admet-2088	241	25	fluidity	fluidity	NOUN
admet-2088	241	26	,	,	PUNCT
admet-2088	241	27	regulating	regulate	VERB
admet-2088	241	28	the	the	DET
admet-2088	241	29	cell	cell	NOUN
admet-2088	241	30	cycle	cycle	NOUN
admet-2088	241	31	,	,	PUNCT
admet-2088	241	32	autophagy	autophagy	VERB
admet-2088	241	33	in	in	ADP
admet-2088	241	34	cancer	cancer	NOUN
admet-2088	241	35	cells	cell	NOUN
admet-2088	241	36	and	and	CCONJ
admet-2088	241	37	suppressing	suppress	VERB
admet-2088	241	38	antiapoptotic	antiapoptotic	ADJ
admet-2088	241	39	genes	gene	NOUN
admet-2088	241	40	[	[	X
admet-2088	241	41	92	92	NUM
admet-2088	241	42	-	-	SYM
admet-2088	241	43	94	94	NUM
admet-2088	241	44	]	]	PUNCT
admet-2088	241	45	.	.	PUNCT
admet-2088	242	1	in	in	ADP
admet-2088	242	2	addition	addition	NOUN
admet-2088	242	3	,	,	PUNCT
admet-2088	242	4	these	these	DET
admet-2088	242	5	nps	nps	PROPN
admet-2088	242	6	regenerate	regenerate	ADJ
admet-2088	242	7	cell	cell	NOUN
admet-2088	242	8	atp	atp	PROPN
admet-2088	242	9	,	,	PUNCT
admet-2088	242	10	thereby	thereby	ADV
admet-2088	242	11	causing	cause	VERB
admet-2088	242	12	increasing	increase	VERB
admet-2088	242	13	oxygen	oxygen	NOUN
admet-2088	242	14	production	production	NOUN
admet-2088	242	15	and	and	CCONJ
admet-2088	242	16	mitochondrial	mitochondrial	ADJ
admet-2088	242	17	damage	damage	NOUN
admet-2088	242	18	.	.	PUNCT
admet-2088	243	1	moreover	moreover	ADV
admet-2088	243	2	,	,	PUNCT
admet-2088	243	3	silver	silver	PROPN
admet-2088	243	4	nps	nps	PROPN
admet-2088	243	5	stop	stop	VERB
admet-2088	243	6	the	the	DET
admet-2088	243	7	cell	cell	NOUN
admet-2088	243	8	in	in	ADP
admet-2088	243	9	the	the	DET
admet-2088	243	10	balancing	balancing	NOUN
admet-2088	243	11	phase	phase	NOUN
admet-2088	243	12	of	of	ADP
admet-2088	243	13	gm	gm	PROPN
admet-2088	243	14	,	,	PUNCT
admet-2088	243	15	which	which	PRON
admet-2088	243	16	is	be	AUX
admet-2088	243	17	attributed	attribute	VERB
admet-2088	243	18	to	to	ADP
admet-2088	243	19	dna	dna	PROPN
admet-2088	243	20	damage	damage	NOUN
admet-2088	243	21	[	[	X
admet-2088	243	22	95,96	95,96	NOUN
admet-2088	243	23	]	]	X
admet-2088	243	24	.	.	PUNCT
admet-2088	244	1	silver	silver	PROPN
admet-2088	244	2	nps	nps	PROPN
admet-2088	244	3	coated	coat	VERB
admet-2088	244	4	with	with	ADP
admet-2088	244	5	anticancer	anticancer	NOUN
admet-2088	244	6	agents	agent	NOUN
admet-2088	244	7	can	can	AUX
admet-2088	244	8	efficiently	efficiently	ADV
admet-2088	244	9	destroy	destroy	VERB
admet-2088	244	10	cancer	cancer	NOUN
admet-2088	244	11	cells	cell	NOUN
admet-2088	244	12	by	by	ADP
admet-2088	244	13	delivering	deliver	VERB
admet-2088	244	14	the	the	DET
admet-2088	244	15	drug	drug	NOUN
admet-2088	244	16	to	to	ADP
admet-2088	244	17	the	the	DET
admet-2088	244	18	targeted	target	VERB
admet-2088	244	19	sites	site	NOUN
admet-2088	244	20	[	[	X
admet-2088	244	21	97	97	NUM
admet-2088	244	22	]	]	PUNCT
admet-2088	244	23	.	.	PUNCT
admet-2088	245	1	based	base	VERB
admet-2088	245	2	on	on	ADP
admet-2088	245	3	the	the	DET
admet-2088	245	4	above	above	ADJ
admet-2088	245	5	fact	fact	NOUN
admet-2088	245	6	,	,	PUNCT
admet-2088	245	7	zhao	zhao	PROPN
admet-2088	245	8	et	et	PROPN
admet-2088	245	9	al	al	PROPN
admet-2088	245	10	.	.	PUNCT
admet-2088	246	1	[	[	X
admet-2088	246	2	98	98	NUM
admet-2088	246	3	]	]	PUNCT
admet-2088	246	4	developed	develop	VERB
admet-2088	246	5	a	a	DET
admet-2088	246	6	spherical	spherical	ADJ
admet-2088	246	7	-	-	PUNCT
admet-2088	246	8	shaped	shape	VERB
admet-2088	246	9	nanocomposite	nanocomposite	NOUN
admet-2088	246	10	comprised	comprise	VERB
admet-2088	246	11	of	of	ADP
admet-2088	246	12	silver	silver	PROPN
admet-2088	246	13	nps	nps	PROPN
admet-2088	246	14	and	and	CCONJ
admet-2088	246	15	chitosan	chitosan	ADJ
admet-2088	246	16	-	-	PUNCT
admet-2088	246	17	starch	starch	NOUN
admet-2088	246	18	biocomposite	biocomposite	NOUN
admet-2088	246	19	hydrogel	hydrogel	NOUN
admet-2088	246	20	.	.	PUNCT
admet-2088	247	1	silver	silver	PROPN
admet-2088	247	2	nps	nps	PROPN
admet-2088	247	3	were	be	AUX
admet-2088	247	4	monodispersed	monodisperse	VERB
admet-2088	247	5	with	with	ADP
admet-2088	247	6	particle	particle	NOUN
admet-2088	247	7	sizes	size	NOUN
admet-2088	247	8	ranging	range	VERB
admet-2088	247	9	from	from	ADP
admet-2088	247	10	5	5	NUM
admet-2088	247	11	nm	nm	NOUN
admet-2088	247	12	to	to	ADP
admet-2088	247	13	15	15	NUM
admet-2088	247	14	nm	nm	NOUN
admet-2088	247	15	and	and	CCONJ
admet-2088	247	16	were	be	AUX
admet-2088	247	17	uniformly	uniformly	ADV
admet-2088	247	18	distributed	distribute	VERB
admet-2088	247	19	and	and	CCONJ
admet-2088	247	20	stabilized	stabilize	VERB
admet-2088	247	21	by	by	ADP
admet-2088	247	22	the	the	DET
admet-2088	247	23	hydrogel	hydrogel	NOUN
admet-2088	247	24	matrix	matrix	NOUN
admet-2088	247	25	.	.	PUNCT
admet-2088	248	1	these	these	DET
admet-2088	248	2	nps	nps	PROPN
admet-2088	248	3	showed	show	VERB
admet-2088	248	4	excellent	excellent	ADJ
admet-2088	248	5	antioxidant	antioxidant	ADJ
admet-2088	248	6	properties	property	NOUN
admet-2088	248	7	related	relate	VERB
admet-2088	248	8	to	to	ADP
admet-2088	248	9	the	the	DET
admet-2088	248	10	quenching	quenching	NOUN
admet-2088	248	11	of	of	ADP
admet-2088	248	12	free	free	ADJ
admet-2088	248	13	radicals	radical	NOUN
admet-2088	248	14	.	.	PUNCT
admet-2088	249	1	when	when	SCONJ
admet-2088	249	2	these	these	DET
admet-2088	249	3	nps	nps	PROPN
admet-2088	249	4	were	be	AUX
admet-2088	249	5	studied	study	VERB
admet-2088	249	6	for	for	ADP
admet-2088	249	7	anti	anti	ADJ
admet-2088	249	8	-	-	ADJ
admet-2088	249	9	melanoma	melanoma	ADJ
admet-2088	249	10	effect	effect	NOUN
admet-2088	249	11	using	use	VERB
admet-2088	249	12	six	six	NUM
admet-2088	249	13	different	different	ADJ
admet-2088	249	14	types	type	NOUN
admet-2088	249	15	of	of	ADP
admet-2088	249	16	malignant	malignant	ADJ
admet-2088	249	17	melanoma	melanoma	NOUN
admet-2088	249	18	cell	cell	NOUN
admet-2088	249	19	lines	line	NOUN
admet-2088	249	20	,	,	PUNCT
admet-2088	249	21	the	the	DET
admet-2088	249	22	percentage	percentage	NOUN
admet-2088	249	23	of	of	ADP
admet-2088	249	24	cell	cell	NOUN
admet-2088	249	25	viability	viability	NOUN
admet-2088	249	26	was	be	AUX
admet-2088	249	27	found	find	VERB
admet-2088	249	28	to	to	PART
admet-2088	249	29	decrease	decrease	VERB
admet-2088	249	30	in	in	ADP
admet-2088	249	31	a	a	DET
admet-2088	249	32	dose	dose	NOUN
admet-2088	249	33	-	-	PUNCT
admet-2088	249	34	dependent	dependent	ADJ
admet-2088	249	35	manner	manner	NOUN
admet-2088	249	36	.	.	PUNCT
admet-2088	250	1	patil	patil	PROPN
admet-2088	250	2	et	et	PROPN
admet-2088	250	3	al	al	PROPN
admet-2088	250	4	.	.	PUNCT
admet-2088	251	1	[	[	X
admet-2088	251	2	99	99	NUM
admet-2088	251	3	]	]	PUNCT
admet-2088	251	4	fabricated	fabricate	VERB
admet-2088	251	5	a	a	DET
admet-2088	251	6	multimodal	multimodal	ADJ
admet-2088	251	7	theranostic	theranostic	ADJ
admet-2088	251	8	agent	agent	NOUN
admet-2088	251	9	with	with	ADP
admet-2088	251	10	an	an	DET
admet-2088	251	11	organometallic	organometallic	ADJ
admet-2088	251	12	system	system	NOUN
admet-2088	251	13	;	;	PUNCT
admet-2088	251	14	silver	silver	PROPN
admet-2088	251	15	nps	nps	PROPN
admet-2088	251	16	as	as	SCONJ
admet-2088	251	17	metallic	metallic	ADJ
admet-2088	251	18	component	component	NOUN
admet-2088	251	19	provide	provide	VERB
admet-2088	251	20	photothermal	photothermal	ADJ
admet-2088	251	21	ablation	ablation	NOUN
admet-2088	251	22	of	of	ADP
admet-2088	251	23	cancer	cancer	NOUN
admet-2088	251	24	cells	cell	NOUN
admet-2088	251	25	and	and	CCONJ
admet-2088	251	26	pheophorbide	pheophorbide	NOUN
admet-2088	251	27	-	-	PUNCT
admet-2088	251	28	a(ph	a(ph	NOUN
admet-2088	251	29	-	-	PUNCT
admet-2088	251	30	a	a	NOUN
admet-2088	251	31	)	)	PUNCT
admet-2088	251	32	as	as	ADP
admet-2088	251	33	an	an	DET
admet-2088	251	34	organic	organic	ADJ
admet-2088	251	35	component	component	NOUN
admet-2088	251	36	provide	provide	VERB
admet-2088	251	37	chemotherapeutic	chemotherapeutic	ADJ
admet-2088	251	38	and	and	CCONJ
admet-2088	251	39	imaging	imaging	NOUN
admet-2088	251	40	activity	activity	NOUN
admet-2088	251	41	.	.	PUNCT
admet-2088	252	1	in	in	ADP
admet-2088	252	2	vitro	vitro	X
admet-2088	252	3	studies	study	NOUN
admet-2088	252	4	on	on	ADP
admet-2088	252	5	cell	cell	NOUN
admet-2088	252	6	lines	line	NOUN
admet-2088	252	7	demonstrated	demonstrate	VERB
admet-2088	252	8	that	that	SCONJ
admet-2088	252	9	these	these	DET
admet-2088	252	10	nanosystems	nanosystem	NOUN
admet-2088	252	11	caused	cause	VERB
admet-2088	252	12	apoptotic	apoptotic	ADJ
admet-2088	252	13	cell	cell	NOUN
admet-2088	252	14	death	death	NOUN
admet-2088	252	15	due	due	ADP
admet-2088	252	16	to	to	ADP
admet-2088	252	17	ptt	ptt	NOUN
admet-2088	252	18	-	-	PUNCT
admet-2088	252	19	mediated	mediate	VERB
admet-2088	252	20	ros	ros	NOUN
admet-2088	252	21	formation	formation	NOUN
admet-2088	252	22	.	.	PUNCT
admet-2088	253	1	in	in	ADP
admet-2088	253	2	vivo	vivo	NOUN
admet-2088	253	3	antimelanoma	antimelanoma	NOUN
admet-2088	253	4	study	study	NOUN
admet-2088	253	5	showed	show	VERB
admet-2088	253	6	effective	effective	ADJ
admet-2088	253	7	suppression	suppression	NOUN
admet-2088	253	8	of	of	ADP
admet-2088	253	9	tumour	tumour	NOUN
admet-2088	253	10	growth	growth	NOUN
admet-2088	253	11	,	,	PUNCT
admet-2088	253	12	which	which	PRON
admet-2088	253	13	could	could	AUX
admet-2088	253	14	be	be	AUX
admet-2088	253	15	attributed	attribute	VERB
admet-2088	253	16	to	to	ADP
admet-2088	253	17	the	the	DET
admet-2088	253	18	combined	combine	VERB
admet-2088	253	19	effect	effect	NOUN
admet-2088	253	20	of	of	ADP
admet-2088	253	21	nps	nps	PROPN
admet-2088	253	22	and	and	CCONJ
admet-2088	253	23	ptt	ptt	PROPN
admet-2088	253	24	.	.	PUNCT
admet-2088	254	1	in	in	ADP
admet-2088	254	2	one	one	NUM
admet-2088	254	3	investigation	investigation	NOUN
admet-2088	254	4	,	,	PUNCT
admet-2088	254	5	a	a	DET
admet-2088	254	6	novel	novel	ADJ
admet-2088	254	7	nanohybrid	nanohybrid	NOUN
admet-2088	254	8	bio	bio	PROPN
admet-2088	254	9	-	-	PUNCT
admet-2088	254	10	hydrogel	hydrogel	NOUN
admet-2088	254	11	comprised	comprise	VERB
admet-2088	254	12	of	of	ADP
admet-2088	254	13	silver	silver	PROPN
admet-2088	254	14	nps	nps	PROPN
admet-2088	254	15	embedded	embed	VERB
admet-2088	254	16	in	in	ADP
admet-2088	254	17	carboxymethyl	carboxymethyl	NOUN
admet-2088	254	18	cellulose	cellulose	NOUN
admet-2088	254	19	(	(	PUNCT
admet-2088	254	20	cmc	cmc	PROPN
admet-2088	254	21	)	)	PUNCT
admet-2088	254	22	and	and	CCONJ
admet-2088	254	23	poly(acrylic	poly(acrylic	ADJ
admet-2088	254	24	acid	acid	NOUN
admet-2088	254	25	-	-	PUNCT
admet-2088	254	26	co	co	NOUN
admet-2088	254	27	-	-	ADJ
admet-2088	254	28	maleic	maleic	VERB
admet-2088	254	29	acid	acid	NOUN
admet-2088	254	30	(	(	PUNCT
admet-2088	254	31	ma	ma	PROPN
admet-2088	254	32	)	)	PUNCT
admet-2088	254	33	was	be	AUX
admet-2088	254	34	developed	develop	VERB
admet-2088	254	35	in	in	ADP
admet-2088	254	36	the	the	DET
admet-2088	254	37	presence	presence	NOUN
admet-2088	254	38	of	of	ADP
admet-2088	254	39	octadecylamine	octadecylamine	PROPN
admet-2088	254	40	(	(	PUNCT
admet-2088	254	41	oda	oda	NOUN
admet-2088	254	42	)	)	PUNCT
admet-2088	254	43	using	use	VERB
admet-2088	254	44	a	a	DET
admet-2088	254	45	soft	soft	ADJ
admet-2088	254	46	white	white	ADJ
admet-2088	254	47	led	lead	VERB
admet-2088	254	48	approach	approach	NOUN
admet-2088	254	49	(	(	PUNCT
admet-2088	254	50	agnps@c	agnps@c	PROPN
admet-2088	254	51	-	-	PUNCT
admet-2088	254	52	ma	ma	PROPN
admet-2088	254	53	-	-	PROPN
admet-2088	254	54	o	o	NOUN
admet-2088	254	55	)	)	PUNCT
admet-2088	254	56	.	.	PUNCT
admet-2088	255	1	the	the	DET
admet-2088	255	2	hybrid	hybrid	ADJ
admet-2088	255	3	hydrogel	hydrogel	NOUN
admet-2088	255	4	was	be	AUX
admet-2088	255	5	tested	test	VERB
admet-2088	255	6	for	for	ADP
admet-2088	255	7	its	its	PRON
admet-2088	255	8	potency	potency	NOUN
admet-2088	255	9	against	against	ADP
admet-2088	255	10	human	human	ADJ
admet-2088	255	11	melanoma	melanoma	NOUN
admet-2088	255	12	cells	cell	NOUN
admet-2088	255	13	and	and	CCONJ
admet-2088	255	14	the	the	DET
admet-2088	255	15	results	result	NOUN
admet-2088	255	16	demonstrated	demonstrate	VERB
admet-2088	255	17	that	that	SCONJ
admet-2088	255	18	the	the	DET
admet-2088	255	19	systems	system	NOUN
admet-2088	255	20	reduced	reduce	VERB
admet-2088	255	21	viability	viability	NOUN
admet-2088	255	22	of	of	ADP
admet-2088	255	23	skin	skin	NOUN
admet-2088	255	24	melanoma	melanoma	NOUN
admet-2088	255	25	cells	cell	NOUN
admet-2088	255	26	in	in	ADP
admet-2088	255	27	a	a	DET
admet-2088	255	28	dose	dose	NOUN
admet-2088	255	29	and	and	CCONJ
admet-2088	255	30	time	time	NOUN
admet-2088	255	31	-	-	PUNCT
admet-2088	255	32	dependent	dependent	ADJ
admet-2088	255	33	manner	manner	NOUN
admet-2088	255	34	.	.	PUNCT
admet-2088	256	1	the	the	DET
admet-2088	256	2	result	result	NOUN
admet-2088	256	3	was	be	AUX
admet-2088	256	4	attributed	attribute	VERB
admet-2088	256	5	to	to	ADP
admet-2088	256	6	the	the	DET
admet-2088	256	7	generation	generation	NOUN
admet-2088	256	8	of	of	ADP
admet-2088	256	9	ros	ros	PROPN
admet-2088	256	10	and	and	CCONJ
admet-2088	256	11	subsequent	subsequent	ADJ
admet-2088	256	12	damage	damage	NOUN
admet-2088	256	13	to	to	ADP
admet-2088	256	14	cell	cell	NOUN
admet-2088	256	15	or	or	CCONJ
admet-2088	256	16	mitochondrial	mitochondrial	ADJ
admet-2088	256	17	membranes	membrane	NOUN
admet-2088	256	18	,	,	PUNCT
admet-2088	256	19	resulting	result	VERB
admet-2088	256	20	in	in	ADP
admet-2088	256	21	cell	cell	NOUN
admet-2088	256	22	deaths	death	NOUN
admet-2088	256	23	.	.	PUNCT
admet-2088	257	1	further	far	ADV
admet-2088	257	2	,	,	PUNCT
admet-2088	257	3	the	the	DET
admet-2088	257	4	use	use	NOUN
admet-2088	257	5	of	of	ADP
admet-2088	257	6	harmless	harmless	ADJ
admet-2088	257	7	white	white	NOUN
admet-2088	257	8	led	lead	VERB
admet-2088	257	9	in	in	ADP
admet-2088	257	10	the	the	DET
admet-2088	257	11	synthesis	synthesis	NOUN
admet-2088	257	12	process	process	NOUN
admet-2088	257	13	enhanced	enhance	VERB
admet-2088	257	14	the	the	DET
admet-2088	257	15	synergy	synergy	NOUN
admet-2088	257	16	between	between	ADP
admet-2088	257	17	silver	silver	PROPN
admet-2088	257	18	nps	nps	PROPN
admet-2088	257	19	and	and	CCONJ
admet-2088	257	20	biopolymers	biopolymer	NOUN
admet-2088	257	21	and	and	CCONJ
admet-2088	257	22	thereby	thereby	ADV
admet-2088	257	23	enhanced	enhance	VERB
admet-2088	257	24	the	the	DET
admet-2088	257	25	anticancer	anticancer	NOUN
admet-2088	257	26	efficiency	efficiency	NOUN
admet-2088	257	27	of	of	ADP
admet-2088	257	28	the	the	DET
admet-2088	257	29	nanohybrid	nanohybrid	NOUN
admet-2088	257	30	hydrogel	hydrogel	NOUN
admet-2088	257	31	[	[	X
admet-2088	257	32	100	100	NUM
admet-2088	257	33	]	]	PUNCT
admet-2088	257	34	.	.	PUNCT
admet-2088	258	1	another	another	DET
admet-2088	258	2	nanohybrid	nanohybrid	NOUN
admet-2088	258	3	hydrogel	hydrogel	NOUN
admet-2088	258	4	system	system	NOUN
admet-2088	258	5	with	with	ADP
admet-2088	258	6	silver	silver	PROPN
admet-2088	258	7	nps	nps	PROPN
admet-2088	258	8	embedded	embed	VERB
admet-2088	258	9	in	in	ADP
admet-2088	258	10	cross	cross	ADJ
admet-2088	258	11	-	-	ADJ
admet-2088	258	12	linking	linking	ADJ
admet-2088	258	13	networks	network	NOUN
admet-2088	258	14	of	of	ADP
admet-2088	258	15	cmc	cmc	NOUN
admet-2088	258	16	conjugated	conjugate	VERB
admet-2088	258	17	with	with	ADP
admet-2088	258	18	doxorubicin	doxorubicin	PROPN
admet-2088	258	19	was	be	AUX
admet-2088	258	20	developed	develop	VERB
admet-2088	258	21	.	.	PUNCT
admet-2088	259	1	the	the	DET
admet-2088	259	2	nanohybrid	nanohybrid	NOUN
admet-2088	259	3	system	system	NOUN
admet-2088	259	4	was	be	AUX
admet-2088	259	5	synthesized	synthesize	VERB
admet-2088	259	6	using	use	VERB
admet-2088	259	7	a	a	DET
admet-2088	259	8	single	single	ADJ
admet-2088	259	9	-	-	PUNCT
admet-2088	259	10	pot	pot	NOUN
admet-2088	259	11	in	in	ADP
admet-2088	259	12	-	-	PUNCT
admet-2088	259	13	situ	situ	NOUN
admet-2088	259	14	reduction	reduction	NOUN
admet-2088	259	15	of	of	ADP
admet-2088	259	16	silver	silver	ADJ
admet-2088	259	17	ions	ion	NOUN
admet-2088	259	18	by	by	ADP
admet-2088	259	19	cmc	cmc	NOUN
admet-2088	259	20	polymer	polymer	NOUN
admet-2088	259	21	(	(	PUNCT
admet-2088	259	22	a	a	DET
admet-2088	259	23	green	green	ADJ
admet-2088	259	24	process	process	NOUN
admet-2088	259	25	)	)	PUNCT
admet-2088	259	26	,	,	PUNCT
admet-2088	259	27	which	which	PRON
admet-2088	259	28	is	be	AUX
admet-2088	259	29	also	also	ADV
admet-2088	259	30	used	use	VERB
admet-2088	259	31	as	as	ADP
admet-2088	259	32	a	a	DET
admet-2088	259	33	capping	capping	NOUN
admet-2088	259	34	ligand	ligand	NOUN
admet-2088	259	35	and	and	CCONJ
admet-2088	259	36	then	then	ADV
admet-2088	259	37	electrostatic	electrostatic	ADJ
admet-2088	259	38	conjugation	conjugation	NOUN
admet-2088	259	39	with	with	ADP
admet-2088	259	40	doxorubicin	doxorubicin	PROPN
admet-2088	259	41	.	.	PUNCT
admet-2088	260	1	these	these	DET
admet-2088	260	2	systems	system	NOUN
admet-2088	260	3	showed	showed	AUX
admet-2088	260	4	tuned	tune	VERB
admet-2088	260	5	doxorubicin	doxorubicin	PROPN
admet-2088	260	6	intracellular	intracellular	ADJ
admet-2088	260	7	kinetic	kinetic	NOUN
admet-2088	260	8	in	in	ADP
admet-2088	260	9	vitro	vitro	NOUN
admet-2088	260	10	,	,	PUNCT
admet-2088	260	11	indicating	indicate	VERB
admet-2088	260	12	a	a	DET
admet-2088	260	13	synergistic	synergistic	ADJ
admet-2088	260	14	effect	effect	NOUN
admet-2088	260	15	with	with	ADP
admet-2088	260	16	silver	silver	PROPN
admet-2088	260	17	nps	nps	PROPN
admet-2088	260	18	in	in	ADP
admet-2088	260	19	killing	kill	VERB
admet-2088	260	20	melanoma	melanoma	NOUN
admet-2088	260	21	cells	cell	NOUN
admet-2088	260	22	.	.	PUNCT
admet-2088	261	1	in	in	ADP
admet-2088	261	2	addition	addition	NOUN
admet-2088	261	3	,	,	PUNCT
admet-2088	261	4	this	this	DET
admet-2088	261	5	nanohybrid	nanohybrid	NOUN
admet-2088	261	6	system	system	NOUN
admet-2088	261	7	also	also	ADV
admet-2088	261	8	showed	show	VERB
admet-2088	261	9	significant	significant	ADJ
admet-2088	261	10	antibacterial	antibacterial	ADJ
admet-2088	261	11	activity	activity	NOUN
admet-2088	261	12	against	against	ADP
admet-2088	261	13	both	both	PRON
admet-2088	261	14	gram+ve	gram+ve	NOUN
admet-2088	261	15	and	and	CCONJ
admet-2088	261	16	gram	gram	PROPN
admet-2088	261	17	-	-	PUNCT
admet-2088	261	18	ve	ve	PROPN
admet-2088	261	19	bacteria	bacteria	NOUN
admet-2088	261	20	responsible	responsible	ADJ
admet-2088	261	21	for	for	ADP
admet-2088	261	22	associated	associated	ADJ
admet-2088	261	23	infection	infection	NOUN
admet-2088	261	24	at	at	ADP
admet-2088	261	25	the	the	DET
admet-2088	261	26	melanoma	melanoma	NOUN
admet-2088	261	27	sites	site	NOUN
admet-2088	261	28	[	[	X
admet-2088	261	29	101	101	NUM
admet-2088	261	30	]	]	PUNCT
admet-2088	261	31	.	.	PUNCT
admet-2088	262	1	valenzuela	valenzuela	PROPN
admet-2088	262	2	-	-	PUNCT
admet-2088	262	3	salas	salas	PROPN
admet-2088	262	4	et	et	NOUN
admet-2088	262	5	al	al	PROPN
admet-2088	262	6	.	.	PUNCT
admet-2088	263	1	[	[	X
admet-2088	263	2	102	102	NUM
admet-2088	263	3	]	]	PUNCT
admet-2088	263	4	studied	study	VERB
admet-2088	263	5	the	the	DET
admet-2088	263	6	antiproliferative	antiproliferative	NOUN
admet-2088	263	7	and	and	CCONJ
admet-2088	263	8	antitumor	antitumor	NOUN
admet-2088	263	9	effects	effect	NOUN
admet-2088	263	10	of	of	ADP
admet-2088	263	11	silver	silver	PROPN
admet-2088	263	12	nps	nps	PROPN
admet-2088	263	13	coated	coat	VERB
admet-2088	263	14	with	with	ADP
admet-2088	263	15	polyvinylpyrrolidone	polyvinylpyrrolidone	PROPN
admet-2088	263	16	(	(	PUNCT
admet-2088	263	17	pvp	pvp	PROPN
admet-2088	263	18	)	)	PUNCT
admet-2088	263	19	and	and	CCONJ
admet-2088	263	20	compared	compare	VERB
admet-2088	263	21	the	the	DET
admet-2088	263	22	result	result	NOUN
admet-2088	263	23	with	with	ADP
admet-2088	263	24	cisplatin	cisplatin	NOUN
admet-2088	263	25	activity	activity	NOUN
admet-2088	263	26	.	.	PUNCT
admet-2088	264	1	the	the	DET
admet-2088	264	2	coated	coated	ADJ
admet-2088	264	3	silver	silver	PROPN
admet-2088	264	4	nps	nps	PROPN
admet-2088	264	5	have	have	VERB
admet-2088	264	6	an	an	DET
admet-2088	264	7	average	average	ADJ
admet-2088	264	8	particle	particle	NOUN
admet-2088	264	9	size	size	NOUN
admet-2088	264	10	of	of	ADP
admet-2088	264	11	35±15	35±15	NUM
admet-2088	264	12	nm	nm	ADJ
admet-2088	264	13	and	and	CCONJ
admet-2088	264	14	metallic	metallic	ADJ
admet-2088	264	15	silver	silver	NOUN
admet-2088	264	16	content	content	NOUN
admet-2088	264	17	of	of	ADP
admet-2088	264	18	1.2	1.2	NUM
admet-2088	264	19	wt%	wt%	ADJ
admet-2088	264	20	.	.	PUNCT
admet-2088	265	1	similar	similar	ADJ
admet-2088	265	2	responses	response	NOUN
admet-2088	265	3	for	for	ADP
admet-2088	265	4	antiproliferative	antiproliferative	ADJ
admet-2088	265	5	potency	potency	NOUN
admet-2088	265	6	and	and	CCONJ
admet-2088	265	7	ros	ros	PROPN
admet-2088	265	8	production	production	NOUN
admet-2088	265	9	were	be	AUX
admet-2088	265	10	observed	observe	VERB
admet-2088	265	11	for	for	ADP
admet-2088	265	12	both	both	CCONJ
admet-2088	265	13	coated	coated	ADJ
admet-2088	265	14	silver	silver	PROPN
admet-2088	265	15	nps	nps	PROPN
admet-2088	265	16	and	and	CCONJ
admet-2088	265	17	cisplatin	cisplatin	NOUN
admet-2088	265	18	.	.	PUNCT
admet-2088	266	1	however	however	ADV
admet-2088	266	2	,	,	PUNCT
admet-2088	266	3	significantly	significantly	ADV
admet-2088	266	4	different	different	ADJ
admet-2088	266	5	cell	cell	NOUN
admet-2088	266	6	death	death	NOUN
admet-2088	266	7	pathways	pathway	NOUN
admet-2088	266	8	were	be	AUX
admet-2088	266	9	triggered	trigger	VERB
admet-2088	266	10	,	,	PUNCT
admet-2088	266	11	which	which	PRON
admet-2088	266	12	was	be	AUX
admet-2088	266	13	attributed	attribute	VERB
admet-2088	266	14	to	to	ADP
admet-2088	266	15	the	the	DET
admet-2088	266	16	induction	induction	NOUN
admet-2088	266	17	of	of	ADP
admet-2088	266	18	apoptosis	apoptosis	NOUN
admet-2088	266	19	and	and	CCONJ
admet-2088	266	20	necrosis	necrosis	NOUN
admet-2088	266	21	by	by	ADP
admet-2088	266	22	cisplatin	cisplatin	NOUN
admet-2088	266	23	,	,	PUNCT
admet-2088	266	24	while	while	SCONJ
admet-2088	266	25	only	only	ADV
admet-2088	266	26	apoptosis	apoptosis	NOUN
admet-2088	266	27	was	be	AUX
admet-2088	266	28	induced	induce	VERB
admet-2088	266	29	by	by	ADP
admet-2088	266	30	silver	silver	PROPN
admet-2088	266	31	nps	nps	PROPN
admet-2088	266	32	.	.	PUNCT
admet-2088	267	1	in	in	ADP
admet-2088	267	2	addition	addition	NOUN
admet-2088	267	3	,	,	PUNCT
admet-2088	267	4	silver	silver	PROPN
admet-2088	267	5	nps	nps	PROPN
admet-2088	267	6	showed	show	VERB
admet-2088	267	7	a	a	DET
admet-2088	267	8	survival	survival	NOUN
admet-2088	267	9	rate	rate	NOUN
admet-2088	267	10	almost	almost	ADV
admet-2088	267	11	4	4	NUM
admet-2088	267	12	-	-	ADJ
admet-2088	267	13	fold	fold	VERB
admet-2088	267	14	higher	high	ADJ
admet-2088	267	15	compared	compare	VERB
admet-2088	267	16	with	with	ADP
admet-2088	267	17	the	the	DET
admet-2088	267	18	survival	survival	NOUN
admet-2088	267	19	rate	rate	NOUN
admet-2088	267	20	observed	observe	VERB
admet-2088	267	21	with	with	ADP
admet-2088	267	22	cisplatin	cisplatin	NOUN
admet-2088	267	23	.	.	PUNCT
admet-2088	268	1	moreover	moreover	ADV
admet-2088	268	2	,	,	PUNCT
admet-2088	268	3	the	the	DET
admet-2088	268	4	in	in	ADP
admet-2088	268	5	vivo	vivo	NOUN
admet-2088	268	6	study	study	NOUN
admet-2088	268	7	on	on	ADP
admet-2088	268	8	survivor	survivor	NOUN
admet-2088	268	9	mice	mouse	NOUN
admet-2088	268	10	treated	treat	VERB
admet-2088	268	11	with	with	ADP
admet-2088	268	12	silver	silver	PROPN
admet-2088	268	13	nps	nps	PROPN
admet-2088	268	14	did	do	AUX
admet-2088	268	15	not	not	PART
admet-2088	268	16	demonstrate	demonstrate	VERB
admet-2088	268	17	genotoxic	genotoxic	ADJ
admet-2088	268	18	damage	damage	NOUN
admet-2088	268	19	with	with	ADP
admet-2088	268	20	remarkable	remarkable	ADJ
admet-2088	268	21	anti	anti	ADJ
admet-2088	268	22	-	-	ADJ
admet-2088	268	23	melanoma	melanoma	ADJ
admet-2088	268	24	activity	activity	NOUN
admet-2088	268	25	.	.	PUNCT
admet-2088	269	1	a	a	DET
admet-2088	269	2	nanocomposite	nanocomposite	NOUN
admet-2088	269	3	consisting	consist	VERB
admet-2088	269	4	of	of	ADP
admet-2088	269	5	silver	silver	NOUN
admet-2088	269	6	and	and	CCONJ
admet-2088	269	7	platinum	platinum	NOUN
admet-2088	269	8	inorganic	inorganic	PROPN
admet-2088	269	9	nps	nps	PROPN
admet-2088	269	10	was	be	AUX
admet-2088	269	11	developed	develop	VERB
admet-2088	269	12	for	for	ADP
admet-2088	269	13	its	its	PRON
admet-2088	269	14	anticancer	anticancer	NOUN
admet-2088	269	15	activity	activity	NOUN
admet-2088	269	16	against	against	ADP
admet-2088	269	17	melanoma	melanoma	NOUN
admet-2088	269	18	.	.	PUNCT
admet-2088	270	1	the	the	DET
admet-2088	270	2	anti	anti	ADJ
admet-2088	270	3	-	-	ADJ
admet-2088	270	4	melanoma	melanoma	ADJ
admet-2088	270	5	activity	activity	NOUN
admet-2088	270	6	on	on	ADP
admet-2088	270	7	the	the	DET
admet-2088	270	8	melanoma	melanoma	NOUN
admet-2088	270	9	cell	cell	NOUN
admet-2088	270	10	line	line	NOUN
admet-2088	270	11	was	be	AUX
admet-2088	270	12	due	due	ADJ
admet-2088	270	13	to	to	ADP
admet-2088	270	14	the	the	DET
admet-2088	270	15	effective	effective	ADJ
admet-2088	270	16	interaction	interaction	NOUN
admet-2088	270	17	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	270	18	m.	m.	NOUN
admet-2088	271	1	kulkarni	kulkarni	PROPN
admet-2088	271	2	et	et	PROPN
admet-2088	271	3	al	al	PROPN
admet-2088	271	4	.	.	PROPN
admet-2088	271	5	admet	admet	PROPN
admet-2088	271	6	&	&	CCONJ
admet-2088	271	7	dmpk	dmpk	PROPN
admet-2088	271	8	12(1	12(1	PROPN
admet-2088	271	9	)	)	PUNCT
admet-2088	271	10	(	(	PUNCT
admet-2088	271	11	2024	2024	NUM
admet-2088	271	12	)	)	PUNCT
admet-2088	271	13	107	107	NUM
admet-2088	271	14	-	-	SYM
admet-2088	271	15	150	150	NUM
admet-2088	271	16	118	118	NUM
admet-2088	271	17	between	between	ADP
admet-2088	271	18	these	these	DET
admet-2088	271	19	nanocomposites	nanocomposite	NOUN
admet-2088	271	20	and	and	CCONJ
admet-2088	271	21	cell	cell	NOUN
admet-2088	271	22	membranes	membrane	NOUN
admet-2088	271	23	,	,	PUNCT
admet-2088	271	24	killing	kill	VERB
admet-2088	271	25	the	the	DET
admet-2088	271	26	cancer	cancer	NOUN
admet-2088	271	27	cells	cell	NOUN
admet-2088	271	28	and	and	CCONJ
admet-2088	271	29	preventing	prevent	VERB
admet-2088	271	30	metastasis	metastasis	NOUN
admet-2088	271	31	.	.	PUNCT
admet-2088	272	1	the	the	DET
admet-2088	272	2	selectivity	selectivity	NOUN
admet-2088	272	3	of	of	ADP
admet-2088	272	4	cytotoxicity	cytotoxicity	NOUN
admet-2088	272	5	of	of	ADP
admet-2088	272	6	these	these	DET
admet-2088	272	7	nps	nps	PROPN
admet-2088	272	8	towards	towards	ADP
admet-2088	272	9	cancer	cancer	NOUN
admet-2088	272	10	cells	cell	NOUN
admet-2088	272	11	could	could	AUX
admet-2088	272	12	be	be	AUX
admet-2088	272	13	attributed	attribute	VERB
admet-2088	272	14	to	to	ADP
admet-2088	272	15	the	the	DET
admet-2088	272	16	targeting	targeting	NOUN
admet-2088	272	17	of	of	ADP
admet-2088	272	18	cancer	cancer	NOUN
admet-2088	272	19	cells	cell	NOUN
admet-2088	272	20	through	through	ADP
admet-2088	272	21	enhanced	enhanced	ADJ
admet-2088	272	22	permeability	permeability	NOUN
admet-2088	272	23	and	and	CCONJ
admet-2088	272	24	retention	retention	NOUN
admet-2088	272	25	in	in	ADP
admet-2088	272	26	these	these	DET
admet-2088	272	27	cells	cell	NOUN
admet-2088	272	28	[	[	X
admet-2088	272	29	2	2	NUM
admet-2088	272	30	]	]	PUNCT
admet-2088	272	31	.	.	PUNCT
admet-2088	273	1	copper	copper	NOUN
admet-2088	273	2	nanoparticles	nanoparticle	NOUN
admet-2088	273	3	compared	compare	VERB
admet-2088	273	4	to	to	ADP
admet-2088	273	5	gold	gold	NOUN
admet-2088	273	6	and	and	CCONJ
admet-2088	273	7	silver	silver	NOUN
admet-2088	273	8	,	,	PUNCT
admet-2088	273	9	copper	copper	NOUN
admet-2088	273	10	has	have	VERB
admet-2088	273	11	a	a	DET
admet-2088	273	12	lower	low	ADJ
admet-2088	273	13	cost	cost	NOUN
admet-2088	273	14	and	and	CCONJ
admet-2088	273	15	can	can	AUX
admet-2088	273	16	be	be	AUX
admet-2088	273	17	developed	develop	VERB
admet-2088	273	18	through	through	ADP
admet-2088	273	19	contemporary	contemporary	ADJ
admet-2088	273	20	technologies	technology	NOUN
admet-2088	273	21	,	,	PUNCT
admet-2088	273	22	leading	lead	VERB
admet-2088	273	23	to	to	ADP
admet-2088	273	24	enhanced	enhanced	ADJ
admet-2088	273	25	development	development	NOUN
admet-2088	273	26	of	of	ADP
admet-2088	273	27	cupper	cupper	NOUN
admet-2088	273	28	-	-	PUNCT
admet-2088	273	29	based	base	VERB
admet-2088	273	30	nps	nps	PROPN
admet-2088	273	31	as	as	ADP
admet-2088	273	32	therapeutics	therapeutic	NOUN
admet-2088	273	33	.	.	PUNCT
admet-2088	274	1	in	in	ADP
admet-2088	274	2	addition	addition	NOUN
admet-2088	274	3	,	,	PUNCT
admet-2088	274	4	it	it	PRON
admet-2088	274	5	was	be	AUX
admet-2088	274	6	well	well	ADV
admet-2088	274	7	documented	document	VERB
admet-2088	274	8	that	that	SCONJ
admet-2088	274	9	the	the	DET
admet-2088	274	10	cupper	cupper	NOUN
admet-2088	274	11	-	-	PUNCT
admet-2088	274	12	based	base	VERB
admet-2088	274	13	nps	nps	PROPN
admet-2088	274	14	demonstrated	demonstrate	VERB
admet-2088	274	15	enhanced	enhanced	ADJ
admet-2088	274	16	toxicity	toxicity	NOUN
admet-2088	274	17	against	against	ADP
admet-2088	274	18	microbes	microbe	NOUN
admet-2088	274	19	and	and	CCONJ
admet-2088	274	20	fungi	fungus	NOUN
admet-2088	274	21	[	[	X
admet-2088	274	22	103	103	NUM
admet-2088	274	23	]	]	PUNCT
admet-2088	274	24	.	.	PUNCT
admet-2088	275	1	copper	copper	PROPN
admet-2088	275	2	nps	nps	PROPN
admet-2088	275	3	act	act	NOUN
admet-2088	275	4	against	against	ADP
admet-2088	275	5	tumours	tumour	NOUN
admet-2088	275	6	by	by	ADP
admet-2088	275	7	depleting	deplete	VERB
admet-2088	275	8	intratumoral	intratumoral	ADJ
admet-2088	275	9	glutathione	glutathione	NOUN
admet-2088	275	10	levels	level	NOUN
admet-2088	275	11	for	for	ADP
admet-2088	275	12	enhanced	enhanced	ADJ
admet-2088	275	13	ros	ros	PROPN
admet-2088	275	14	on	on	ADP
admet-2088	275	15	account	account	NOUN
admet-2088	275	16	of	of	ADP
admet-2088	275	17	the	the	DET
admet-2088	275	18	redox	redox	ADJ
admet-2088	275	19	reaction	reaction	NOUN
admet-2088	275	20	between	between	ADP
admet-2088	275	21	copper	copper	NOUN
admet-2088	275	22	ions	ion	NOUN
admet-2088	275	23	and	and	CCONJ
admet-2088	275	24	glutathione	glutathione	NOUN
admet-2088	275	25	[	[	X
admet-2088	275	26	104,105	104,105	NUM
admet-2088	275	27	]	]	PUNCT
admet-2088	275	28	.	.	PUNCT
admet-2088	276	1	in	in	ADP
admet-2088	276	2	addition	addition	NOUN
admet-2088	276	3	,	,	PUNCT
admet-2088	276	4	copper	copper	NOUN
admet-2088	276	5	peroxide	peroxide	NOUN
admet-2088	276	6	(	(	PUNCT
admet-2088	276	7	cuo2	cuo2	PROPN
admet-2088	276	8	)	)	PUNCT
admet-2088	276	9	composed	compose	VERB
admet-2088	276	10	of	of	ADP
admet-2088	276	11	copper	copper	NOUN
admet-2088	276	12	ions	ion	NOUN
admet-2088	276	13	and	and	CCONJ
admet-2088	276	14	peroxide	peroxide	NOUN
admet-2088	276	15	groups	group	NOUN
admet-2088	276	16	,	,	PUNCT
admet-2088	276	17	which	which	PRON
admet-2088	276	18	have	have	AUX
admet-2088	276	19	been	be	AUX
admet-2088	276	20	employed	employ	VERB
admet-2088	276	21	for	for	ADP
admet-2088	276	22	tumour	tumour	NOUN
admet-2088	276	23	-	-	PUNCT
admet-2088	276	24	specific	specific	ADJ
admet-2088	276	25	hydrogen	hydrogen	NOUN
admet-2088	276	26	peroxide	peroxide	NOUN
admet-2088	276	27	(	(	PUNCT
admet-2088	276	28	h2o2	h2o2	NOUN
admet-2088	276	29	)	)	PUNCT
admet-2088	276	30	self	self	NOUN
admet-2088	276	31	-	-	PUNCT
admet-2088	276	32	supplying	supply	VERB
admet-2088	276	33	chemodynamic	chemodynamic	ADJ
admet-2088	276	34	therapy	therapy	NOUN
admet-2088	276	35	(	(	PUNCT
admet-2088	276	36	cdt	cdt	PROPN
admet-2088	276	37	)	)	PUNCT
admet-2088	277	1	[	[	X
admet-2088	277	2	106	106	NUM
admet-2088	277	3	]	]	PUNCT
admet-2088	277	4	.	.	PUNCT
admet-2088	278	1	other	other	ADJ
admet-2088	278	2	forms	form	NOUN
admet-2088	278	3	of	of	ADP
admet-2088	278	4	inorganic	inorganic	ADJ
admet-2088	278	5	copper	copper	NOUN
admet-2088	278	6	-	-	PUNCT
admet-2088	278	7	based	base	VERB
admet-2088	278	8	nms	nms	NOUN
admet-2088	278	9	,	,	PUNCT
admet-2088	278	10	such	such	ADJ
admet-2088	278	11	as	as	ADP
admet-2088	278	12	cus	cus	NOUN
admet-2088	278	13	,	,	PUNCT
admet-2088	278	14	cuco2s4	cuco2s4	ADJ
admet-2088	278	15	,	,	PUNCT
admet-2088	278	16	and	and	CCONJ
admet-2088	278	17	cu2	cu2	NOUN
admet-2088	278	18	-	-	PUNCT
admet-2088	278	19	xse	xse	PROPN
admet-2088	278	20	,	,	PUNCT
admet-2088	278	21	have	have	AUX
admet-2088	278	22	been	be	AUX
admet-2088	278	23	used	use	VERB
admet-2088	278	24	to	to	PART
admet-2088	278	25	create	create	VERB
admet-2088	278	26	hyperthermia	hyperthermia	NOUN
admet-2088	278	27	for	for	ADP
admet-2088	278	28	the	the	DET
admet-2088	278	29	ablation	ablation	NOUN
admet-2088	278	30	of	of	ADP
admet-2088	278	31	tumours	tumours	PROPN
admet-2088	278	32	[	[	X
admet-2088	278	33	21	21	NUM
admet-2088	278	34	]	]	PUNCT
admet-2088	278	35	.	.	PUNCT
admet-2088	279	1	song	song	PROPN
admet-2088	279	2	et	et	PROPN
admet-2088	279	3	al	al	PROPN
admet-2088	279	4	.	.	PUNCT
admet-2088	280	1	[	[	X
admet-2088	280	2	107	107	NUM
admet-2088	280	3	]	]	PUNCT
admet-2088	280	4	investigated	investigate	VERB
admet-2088	280	5	the	the	DET
admet-2088	280	6	potential	potential	NOUN
admet-2088	280	7	of	of	ADP
admet-2088	280	8	cuprous	cuprous	ADJ
admet-2088	280	9	oxide	oxide	NOUN
admet-2088	280	10	nps	nps	PROPN
admet-2088	280	11	(	(	PUNCT
admet-2088	280	12	cu2o	cu2o	PROPN
admet-2088	280	13	-	-	PUNCT
admet-2088	280	14	nps	nps	PROPN
admet-2088	280	15	)	)	PUNCT
admet-2088	280	16	against	against	ADP
admet-2088	280	17	uveal	uveal	ADJ
admet-2088	280	18	melanoma	melanoma	NOUN
admet-2088	280	19	cells	cell	NOUN
admet-2088	280	20	.	.	PUNCT
admet-2088	281	1	after	after	ADP
admet-2088	281	2	application	application	NOUN
admet-2088	281	3	,	,	PUNCT
admet-2088	281	4	these	these	DET
admet-2088	281	5	nps	nps	PROPN
admet-2088	281	6	adsorb	adsorb	VERB
admet-2088	281	7	serum	serum	NOUN
admet-2088	281	8	protein	protein	NOUN
admet-2088	281	9	in	in	ADP
admet-2088	281	10	the	the	DET
admet-2088	281	11	cell	cell	NOUN
admet-2088	281	12	culture	culture	NOUN
admet-2088	281	13	medium	medium	NOUN
admet-2088	281	14	,	,	PUNCT
admet-2088	281	15	followed	follow	VERB
admet-2088	281	16	by	by	ADP
admet-2088	281	17	their	their	PRON
admet-2088	281	18	internalization	internalization	NOUN
admet-2088	281	19	by	by	ADP
admet-2088	281	20	uveal	uveal	ADJ
admet-2088	281	21	melanoma	melanoma	NOUN
admet-2088	281	22	cells	cell	NOUN
admet-2088	281	23	via	via	ADP
admet-2088	281	24	lipid	lipid	NOUN
admet-2088	281	25	-	-	PUNCT
admet-2088	281	26	raft	raft	NOUN
admet-2088	281	27	mediated	mediate	VERB
admet-2088	281	28	endocytosis	endocytosis	NOUN
admet-2088	281	29	.	.	PUNCT
admet-2088	282	1	these	these	DET
admet-2088	282	2	cu2o	cu2o	PROPN
admet-2088	282	3	-	-	PUNCT
admet-2088	282	4	nps	nps	PROPN
admet-2088	282	5	not	not	PART
admet-2088	282	6	only	only	ADV
admet-2088	282	7	inhibit	inhibit	VERB
admet-2088	282	8	cancer	cancer	NOUN
admet-2088	282	9	cell	cell	NOUN
admet-2088	282	10	growth	growth	NOUN
admet-2088	282	11	but	but	CCONJ
admet-2088	282	12	also	also	ADV
admet-2088	282	13	impair	impair	VERB
admet-2088	282	14	the	the	DET
admet-2088	282	15	migration	migration	NOUN
admet-2088	282	16	and	and	CCONJ
admet-2088	282	17	invasion	invasion	NOUN
admet-2088	282	18	ability	ability	NOUN
admet-2088	282	19	of	of	ADP
admet-2088	282	20	the	the	DET
admet-2088	282	21	uveal	uveal	ADJ
admet-2088	282	22	melanoma	melanoma	NOUN
admet-2088	282	23	cell	cell	NOUN
admet-2088	282	24	.	.	PUNCT
admet-2088	283	1	the	the	DET
admet-2088	283	2	result	result	NOUN
admet-2088	283	3	was	be	AUX
admet-2088	283	4	attributed	attribute	VERB
admet-2088	283	5	to	to	ADP
admet-2088	283	6	the	the	DET
admet-2088	283	7	damage	damage	NOUN
admet-2088	283	8	caused	cause	VERB
admet-2088	283	9	by	by	ADP
admet-2088	283	10	these	these	DET
admet-2088	283	11	nps	nps	PROPN
admet-2088	283	12	against	against	ADP
admet-2088	283	13	mitochondria	mitochondria	PROPN
admet-2088	283	14	,	,	PUNCT
admet-2088	283	15	lysosomes	lysosome	NOUN
admet-2088	283	16	and	and	CCONJ
admet-2088	283	17	autophagolysosomes	autophagolysosome	NOUN
admet-2088	283	18	,	,	PUNCT
admet-2088	283	19	resulting	result	VERB
admet-2088	283	20	in	in	ADP
admet-2088	283	21	elevated	elevated	ADJ
admet-2088	283	22	ros	ros	PROPN
admet-2088	283	23	levels	level	NOUN
admet-2088	283	24	and	and	CCONJ
admet-2088	283	25	,	,	PUNCT
admet-2088	283	26	subsequently	subsequently	ADV
admet-2088	283	27	,	,	PUNCT
admet-2088	283	28	apoptosis	apoptosis	NOUN
admet-2088	283	29	and	and	CCONJ
admet-2088	283	30	autophagy	autophagy	NOUN
admet-2088	283	31	of	of	ADP
admet-2088	283	32	the	the	DET
admet-2088	283	33	uveal	uveal	ADJ
admet-2088	283	34	melanoma	melanoma	NOUN
admet-2088	283	35	cells	cell	NOUN
admet-2088	283	36	.	.	PUNCT
admet-2088	284	1	the	the	DET
admet-2088	284	2	tumour	tumour	NOUN
admet-2088	284	3	cell	cell	NOUN
admet-2088	284	4	vaccine	vaccine	NOUN
admet-2088	284	5	is	be	AUX
admet-2088	284	6	a	a	DET
admet-2088	284	7	promising	promising	ADJ
admet-2088	284	8	strategy	strategy	NOUN
admet-2088	284	9	to	to	PART
admet-2088	284	10	activate	activate	VERB
admet-2088	284	11	tumour	tumour	NOUN
admet-2088	284	12	immunity	immunity	NOUN
admet-2088	284	13	,	,	PUNCT
admet-2088	284	14	which	which	PRON
admet-2088	284	15	could	could	AUX
admet-2088	284	16	be	be	AUX
admet-2088	284	17	bone	bone	NOUN
admet-2088	284	18	for	for	ADP
admet-2088	284	19	cancer	cancer	NOUN
admet-2088	284	20	therapy	therapy	NOUN
admet-2088	284	21	.	.	PUNCT
admet-2088	285	1	in	in	ADP
admet-2088	285	2	this	this	DET
admet-2088	285	3	process	process	NOUN
admet-2088	285	4	,	,	PUNCT
admet-2088	285	5	nanoenzymes	nanoenzyme	NOUN
admet-2088	285	6	can	can	AUX
admet-2088	285	7	play	play	VERB
admet-2088	285	8	an	an	DET
admet-2088	285	9	important	important	ADJ
admet-2088	285	10	role	role	NOUN
admet-2088	285	11	in	in	ADP
admet-2088	285	12	catalysis	catalysis	NOUN
admet-2088	285	13	-	-	PUNCT
admet-2088	285	14	immunotherapy	immunotherapy	NOUN
admet-2088	285	15	against	against	ADP
admet-2088	285	16	cancer	cancer	NOUN
admet-2088	285	17	therapy	therapy	NOUN
admet-2088	285	18	.	.	PUNCT
admet-2088	286	1	artificial	artificial	ADJ
admet-2088	286	2	enzymes	enzyme	NOUN
admet-2088	286	3	are	be	AUX
admet-2088	286	4	preferred	prefer	VERB
admet-2088	286	5	over	over	ADP
admet-2088	286	6	natural	natural	ADJ
admet-2088	286	7	ones	one	NOUN
admet-2088	286	8	as	as	SCONJ
admet-2088	286	9	they	they	PRON
admet-2088	286	10	can	can	AUX
admet-2088	286	11	be	be	AUX
admet-2088	286	12	prepared	prepare	VERB
admet-2088	286	13	with	with	ADP
admet-2088	286	14	more	more	ADJ
admet-2088	286	15	ease	ease	NOUN
admet-2088	286	16	,	,	PUNCT
admet-2088	286	17	are	be	AUX
admet-2088	286	18	more	more	ADV
admet-2088	286	19	stable	stable	ADJ
admet-2088	286	20	in	in	ADP
admet-2088	286	21	the	the	DET
admet-2088	286	22	preservation	preservation	NOUN
admet-2088	286	23	process	process	NOUN
admet-2088	286	24	,	,	PUNCT
admet-2088	286	25	and	and	CCONJ
admet-2088	286	26	can	can	AUX
admet-2088	286	27	generate	generate	VERB
admet-2088	286	28	substances	substance	NOUN
admet-2088	286	29	for	for	ADP
admet-2088	286	30	tumour	tumour	NOUN
admet-2088	286	31	therapy	therapy	NOUN
admet-2088	286	32	via	via	ADP
admet-2088	286	33	catalyzing	catalyze	VERB
admet-2088	286	34	chemical	chemical	NOUN
admet-2088	286	35	reactions	reaction	NOUN
admet-2088	286	36	in	in	ADP
admet-2088	286	37	situ	situ	PROPN
admet-2088	286	38	[	[	X
admet-2088	286	39	108,109	108,109	NUM
admet-2088	286	40	]	]	PUNCT
admet-2088	286	41	.	.	PUNCT
admet-2088	287	1	considering	consider	VERB
admet-2088	287	2	the	the	DET
admet-2088	287	3	above	above	ADJ
admet-2088	287	4	fact	fact	NOUN
admet-2088	287	5	,	,	PUNCT
admet-2088	287	6	more	more	ADV
admet-2088	287	7	recently	recently	ADV
admet-2088	287	8	,	,	PUNCT
admet-2088	287	9	fang	fang	PROPN
admet-2088	287	10	et	et	PROPN
admet-2088	287	11	al	al	PROPN
admet-2088	287	12	.	.	PUNCT
admet-2088	288	1	[	[	X
admet-2088	288	2	110	110	NUM
admet-2088	288	3	]	]	PUNCT
admet-2088	288	4	developed	develop	VERB
admet-2088	288	5	a	a	DET
admet-2088	288	6	ferroptosisactivating	ferroptosisactivate	VERB
admet-2088	288	7	vaccine	vaccine	NOUN
admet-2088	288	8	employing	employ	VERB
admet-2088	288	9	artificial	artificial	ADJ
admet-2088	288	10	nanoenzyme	nanoenzyme	NOUN
admet-2088	288	11	copper	copper	NOUN
admet-2088	288	12	telluride	telluride	NOUN
admet-2088	288	13	nps	nps	PROPN
admet-2088	288	14	(	(	PUNCT
admet-2088	288	15	ctnps	ctnps	PROPN
admet-2088	288	16	)	)	PUNCT
admet-2088	288	17	to	to	PART
admet-2088	288	18	induce	induce	VERB
admet-2088	288	19	catalytic	catalytic	ADJ
admet-2088	288	20	immunotherapy	immunotherapy	NOUN
admet-2088	288	21	.	.	PUNCT
admet-2088	289	1	firstly	firstly	ADV
admet-2088	289	2	,	,	PUNCT
admet-2088	289	3	mesoporous	mesoporous	ADJ
admet-2088	289	4	ctnps	ctnps	PROPN
admet-2088	289	5	were	be	AUX
admet-2088	289	6	prepared	prepare	VERB
admet-2088	289	7	,	,	PUNCT
admet-2088	289	8	which	which	PRON
admet-2088	289	9	have	have	VERB
admet-2088	289	10	the	the	DET
admet-2088	289	11	ability	ability	NOUN
admet-2088	289	12	to	to	PART
admet-2088	289	13	release	release	VERB
admet-2088	289	14	copper	copper	NOUN
admet-2088	289	15	ions	ion	NOUN
admet-2088	289	16	to	to	ADP
admet-2088	289	17	catalyze	catalyze	VERB
admet-2088	289	18	ros	ros	PROPN
admet-2088	289	19	accumulation	accumulation	NOUN
admet-2088	289	20	and	and	CCONJ
admet-2088	289	21	glutathione	glutathione	NOUN
admet-2088	289	22	oxidation	oxidation	NOUN
admet-2088	289	23	.	.	PUNCT
admet-2088	290	1	this	this	PRON
admet-2088	290	2	led	lead	VERB
admet-2088	290	3	to	to	ADP
admet-2088	290	4	the	the	DET
admet-2088	290	5	triggering	triggering	NOUN
admet-2088	290	6	of	of	ADP
admet-2088	290	7	ferroptosis	ferroptosis	NOUN
admet-2088	290	8	and	and	CCONJ
admet-2088	290	9	induction	induction	NOUN
admet-2088	290	10	of	of	ADP
admet-2088	290	11	immunogenic	immunogenic	ADJ
admet-2088	290	12	cell	cell	NOUN
admet-2088	290	13	death	death	NOUN
admet-2088	290	14	for	for	ADP
admet-2088	290	15	antigens	antigen	NOUN
admet-2088	290	16	and	and	CCONJ
admet-2088	290	17	eliciting	elicit	VERB
admet-2088	290	18	damage	damage	NOUN
admet-2088	290	19	-	-	PUNCT
admet-2088	290	20	associated	associate	VERB
admet-2088	290	21	molecular	molecular	ADJ
admet-2088	290	22	patterns	pattern	NOUN
admet-2088	290	23	.	.	PUNCT
admet-2088	291	1	thereafter	thereafter	ADV
admet-2088	291	2	,	,	PUNCT
admet-2088	291	3	the	the	DET
admet-2088	291	4	ctnps	ctnps	NOUN
admet-2088	291	5	were	be	AUX
admet-2088	291	6	loaded	load	VERB
admet-2088	291	7	with	with	ADP
admet-2088	291	8	ovalbumin	ovalbumin	PROPN
admet-2088	291	9	(	(	PUNCT
admet-2088	291	10	ova	ova	NOUN
admet-2088	291	11	)	)	PUNCT
admet-2088	291	12	(	(	PUNCT
admet-2088	291	13	ctnps@ova	ctnps@ova	X
admet-2088	291	14	)	)	PUNCT
admet-2088	291	15	as	as	ADP
admet-2088	291	16	an	an	DET
admet-2088	291	17	exogenous	exogenous	ADJ
admet-2088	291	18	antigen	antigen	NOUN
admet-2088	291	19	to	to	PART
admet-2088	291	20	boost	boost	VERB
admet-2088	291	21	the	the	DET
admet-2088	291	22	efficacy	efficacy	NOUN
admet-2088	291	23	of	of	ADP
admet-2088	291	24	endogenous	endogenous	ADJ
admet-2088	291	25	antigens	antigen	NOUN
admet-2088	291	26	and	and	CCONJ
admet-2088	291	27	induce	induce	VERB
admet-2088	291	28	a	a	DET
admet-2088	291	29	strong	strong	ADJ
admet-2088	291	30	immune	immune	ADJ
admet-2088	291	31	response	response	NOUN
admet-2088	291	32	in	in	ADP
admet-2088	291	33	vivo	vivo	NOUN
admet-2088	291	34	.	.	PUNCT
admet-2088	292	1	further	far	ADV
admet-2088	292	2	,	,	PUNCT
admet-2088	292	3	ctnps@ova	ctnps@ova	PROPN
admet-2088	292	4	was	be	AUX
admet-2088	292	5	coated	coat	VERB
admet-2088	292	6	with	with	ADP
admet-2088	292	7	melanoma	melanoma	PROPN
admet-2088	292	8	b16ova	b16ova	PROPN
admet-2088	292	9	membrane	membrane	NOUN
admet-2088	292	10	(	(	PUNCT
admet-2088	292	11	cm	cm	NOUN
admet-2088	292	12	ctnps@ova	ctnps@ova	PROPN
admet-2088	292	13	)	)	PUNCT
admet-2088	292	14	to	to	PART
admet-2088	292	15	avoid	avoid	VERB
admet-2088	292	16	the	the	DET
admet-2088	292	17	separation	separation	NOUN
admet-2088	292	18	of	of	ADP
admet-2088	292	19	ova	ova	NOUN
admet-2088	292	20	from	from	ADP
admet-2088	292	21	the	the	DET
admet-2088	292	22	surface	surface	NOUN
admet-2088	292	23	of	of	ADP
admet-2088	292	24	the	the	DET
admet-2088	292	25	nanosystem	nanosystem	NOUN
admet-2088	292	26	.	.	PUNCT
admet-2088	293	1	here	here	ADV
admet-2088	293	2	,	,	PUNCT
admet-2088	293	3	ova	ova	X
admet-2088	293	4	directly	directly	ADV
admet-2088	293	5	induced	induce	VERB
admet-2088	293	6	the	the	DET
admet-2088	293	7	maturation	maturation	NOUN
admet-2088	293	8	of	of	ADP
admet-2088	293	9	dendritic	dendritic	ADJ
admet-2088	293	10	cells	cell	NOUN
admet-2088	293	11	and	and	CCONJ
admet-2088	293	12	subsequent	subsequent	ADJ
admet-2088	293	13	t	t	PROPN
admet-2088	293	14	-	-	PUNCT
admet-2088	293	15	cell	cell	NOUN
admet-2088	293	16	recruitment	recruitment	NOUN
admet-2088	293	17	.	.	PUNCT
admet-2088	294	1	with	with	ADP
admet-2088	294	2	the	the	DET
admet-2088	294	3	addition	addition	NOUN
admet-2088	294	4	of	of	ADP
admet-2088	294	5	ptt	ptt	NOUN
admet-2088	294	6	with	with	ADP
admet-2088	294	7	the	the	DET
admet-2088	294	8	cm	cm	PROPN
admet-2088	294	9	ctnps@ova	ctnps@ova	PROPN
admet-2088	294	10	administration	administration	NOUN
admet-2088	294	11	,	,	PUNCT
admet-2088	294	12	the	the	DET
admet-2088	294	13	function	function	NOUN
admet-2088	294	14	of	of	ADP
admet-2088	294	15	ferroptosis	ferroptosis	NOUN
admet-2088	294	16	-	-	PUNCT
admet-2088	294	17	activating	activate	VERB
admet-2088	294	18	vaccines	vaccine	NOUN
admet-2088	294	19	was	be	AUX
admet-2088	294	20	enhanced	enhance	VERB
admet-2088	294	21	along	along	ADP
admet-2088	294	22	with	with	ADP
admet-2088	294	23	the	the	DET
admet-2088	294	24	generation	generation	NOUN
admet-2088	294	25	of	of	ADP
admet-2088	294	26	strong	strong	ADJ
admet-2088	294	27	immunotherapy	immunotherapy	NOUN
admet-2088	294	28	against	against	ADP
admet-2088	294	29	melanoma	melanoma	NOUN
admet-2088	294	30	.	.	PUNCT
admet-2088	295	1	the	the	DET
admet-2088	295	2	common	common	ADJ
admet-2088	295	3	/	/	SYM
admet-2088	295	4	traditional	traditional	ADJ
admet-2088	295	5	therapies	therapy	NOUN
admet-2088	295	6	such	such	ADJ
admet-2088	295	7	as	as	ADP
admet-2088	295	8	surgery	surgery	NOUN
admet-2088	295	9	,	,	PUNCT
admet-2088	295	10	chemotherapy	chemotherapy	NOUN
admet-2088	295	11	and	and	CCONJ
admet-2088	295	12	radiotherapy	radiotherapy	NOUN
admet-2088	295	13	for	for	ADP
admet-2088	295	14	melanoma	melanoma	NOUN
admet-2088	295	15	suffer	suffer	VERB
admet-2088	295	16	from	from	ADP
admet-2088	295	17	various	various	ADJ
admet-2088	295	18	limitations	limitation	NOUN
admet-2088	295	19	,	,	PUNCT
admet-2088	295	20	including	include	VERB
admet-2088	295	21	serious	serious	ADJ
admet-2088	295	22	systemic	systemic	ADJ
admet-2088	295	23	toxicity	toxicity	NOUN
admet-2088	295	24	,	,	PUNCT
admet-2088	295	25	large	large	ADJ
admet-2088	295	26	defects	defect	NOUN
admet-2088	295	27	to	to	ADP
admet-2088	295	28	the	the	DET
admet-2088	295	29	skin	skin	NOUN
admet-2088	295	30	,	,	PUNCT
admet-2088	295	31	high	high	ADJ
admet-2088	295	32	risk	risk	NOUN
admet-2088	295	33	of	of	ADP
admet-2088	295	34	recurring	recur	VERB
admet-2088	295	35	,	,	PUNCT
admet-2088	295	36	undesirable	undesirable	ADJ
admet-2088	295	37	treatment	treatment	NOUN
admet-2088	295	38	effectiveness	effectiveness	NOUN
admet-2088	295	39	and	and	CCONJ
admet-2088	295	40	therapeutic	therapeutic	ADJ
admet-2088	295	41	resistance	resistance	NOUN
admet-2088	296	1	[	[	X
admet-2088	296	2	14,15	14,15	NUM
admet-2088	296	3	]	]	PUNCT
admet-2088	296	4	.	.	PUNCT
admet-2088	297	1	therefore	therefore	ADV
admet-2088	297	2	,	,	PUNCT
admet-2088	297	3	alternative	alternative	ADJ
admet-2088	297	4	therapeutics	therapeutic	NOUN
admet-2088	297	5	such	such	ADJ
admet-2088	297	6	as	as	ADP
admet-2088	297	7	ptt	ptt	PROPN
admet-2088	297	8	,	,	PUNCT
admet-2088	297	9	pdt	pdt	NOUN
admet-2088	297	10	,	,	PUNCT
admet-2088	297	11	immunotherapy	immunotherapy	NOUN
admet-2088	297	12	,	,	PUNCT
admet-2088	297	13	gene	gene	NOUN
admet-2088	297	14	therapy	therapy	NOUN
admet-2088	297	15	,	,	PUNCT
admet-2088	297	16	etc	etc	X
admet-2088	297	17	.	.	X
admet-2088	297	18	are	be	AUX
admet-2088	297	19	preferred	prefer	VERB
admet-2088	297	20	.	.	PUNCT
admet-2088	298	1	when	when	SCONJ
admet-2088	298	2	administered	administer	VERB
admet-2088	298	3	intravenously	intravenously	ADV
admet-2088	298	4	,	,	PUNCT
admet-2088	298	5	these	these	DET
admet-2088	298	6	therapeutic	therapeutic	ADJ
admet-2088	298	7	agents	agent	NOUN
admet-2088	298	8	accumulate	accumulate	VERB
admet-2088	298	9	at	at	ADP
admet-2088	298	10	the	the	DET
admet-2088	298	11	tumour	tumour	NOUN
admet-2088	298	12	sites	site	NOUN
admet-2088	298	13	in	in	ADP
admet-2088	298	14	low	low	ADJ
admet-2088	298	15	concentration	concentration	NOUN
admet-2088	298	16	due	due	ADP
admet-2088	298	17	to	to	ADP
admet-2088	298	18	the	the	DET
admet-2088	298	19	poor	poor	ADJ
admet-2088	298	20	targeting	target	VERB
admet-2088	298	21	potential	potential	ADJ
admet-2088	298	22	and	and	CCONJ
admet-2088	298	23	intricate	intricate	ADJ
admet-2088	298	24	physiological	physiological	ADJ
admet-2088	298	25	barriers	barrier	NOUN
admet-2088	298	26	,	,	PUNCT
admet-2088	298	27	resulting	result	VERB
admet-2088	298	28	in	in	ADP
admet-2088	298	29	subtherapeutic	subtherapeutic	ADJ
admet-2088	298	30	effects	effect	NOUN
admet-2088	298	31	and	and	CCONJ
admet-2088	298	32	severe	severe	ADJ
admet-2088	298	33	side	side	NOUN
admet-2088	298	34	effects	effect	NOUN
admet-2088	298	35	[	[	X
admet-2088	298	36	111,112	111,112	NUM
admet-2088	298	37	]	]	PUNCT
admet-2088	298	38	.	.	PUNCT
admet-2088	299	1	thus	thus	ADV
admet-2088	299	2	,	,	PUNCT
admet-2088	299	3	a	a	DET
admet-2088	299	4	robust	robust	ADJ
admet-2088	299	5	and	and	CCONJ
admet-2088	299	6	optimized	optimize	VERB
admet-2088	299	7	administration	administration	NOUN
admet-2088	299	8	approach	approach	NOUN
admet-2088	299	9	must	must	AUX
admet-2088	299	10	be	be	AUX
admet-2088	299	11	adopted	adopt	VERB
admet-2088	299	12	for	for	ADP
admet-2088	299	13	tumour	tumour	NOUN
admet-2088	299	14	-	-	PUNCT
admet-2088	299	15	targeted	target	VERB
admet-2088	299	16	delivery	delivery	NOUN
admet-2088	299	17	.	.	PUNCT
admet-2088	300	1	in	in	ADP
admet-2088	300	2	this	this	DET
admet-2088	300	3	context	context	NOUN
admet-2088	300	4	,	,	PUNCT
admet-2088	300	5	microneedle	microneedle	VERB
admet-2088	300	6	systems	system	NOUN
admet-2088	300	7	with	with	ADP
admet-2088	300	8	minimally	minimally	ADV
admet-2088	300	9	invasive	invasive	ADJ
admet-2088	300	10	,	,	PUNCT
admet-2088	300	11	painless	painless	ADJ
admet-2088	300	12	and	and	CCONJ
admet-2088	300	13	efficient	efficient	ADJ
admet-2088	300	14	nature	nature	NOUN
admet-2088	300	15	can	can	AUX
admet-2088	300	16	fulfill	fulfill	VERB
admet-2088	300	17	the	the	DET
admet-2088	300	18	requirements	requirement	NOUN
admet-2088	300	19	.	.	PUNCT
admet-2088	301	1	based	base	VERB
admet-2088	301	2	on	on	ADP
admet-2088	301	3	this	this	DET
admet-2088	301	4	concept	concept	NOUN
admet-2088	301	5	,	,	PUNCT
admet-2088	301	6	chen	chen	PROPN
admet-2088	301	7	et	et	PROPN
admet-2088	301	8	al	al	PROPN
admet-2088	301	9	.	.	PUNCT
admet-2088	302	1	[	[	X
admet-2088	302	2	21	21	NUM
admet-2088	302	3	]	]	PUNCT
admet-2088	302	4	fabricated	fabricate	VERB
admet-2088	302	5	a	a	DET
admet-2088	302	6	microneedle	microneedle	NOUN
admet-2088	302	7	system	system	NOUN
admet-2088	302	8	with	with	ADP
admet-2088	302	9	pvp	pvp	NOUN
admet-2088	302	10	and	and	CCONJ
admet-2088	302	11	cuo2nps	cuo2nps	NOUN
admet-2088	302	12	synthesized	synthesize	VERB
admet-2088	302	13	under	under	ADP
admet-2088	302	14	an	an	DET
admet-2088	302	15	alkaline	alkaline	NOUN
admet-2088	302	16	environment	environment	NOUN
admet-2088	302	17	and	and	CCONJ
admet-2088	302	18	stabilized	stabilize	VERB
admet-2088	302	19	by	by	ADP
admet-2088	302	20	pvp	pvp	PROPN
admet-2088	302	21	.	.	PUNCT
admet-2088	303	1	after	after	ADP
admet-2088	303	2	the	the	DET
admet-2088	303	3	insertion	insertion	NOUN
admet-2088	303	4	of	of	ADP
admet-2088	303	5	microneedles	microneedle	NOUN
admet-2088	303	6	,	,	PUNCT
admet-2088	303	7	admet	admet	PROPN
admet-2088	303	8	&	&	CCONJ
admet-2088	303	9	dmpk	dmpk	PROPN
admet-2088	303	10	12(1	12(1	PROPN
admet-2088	303	11	)	)	PUNCT
admet-2088	303	12	(	(	PUNCT
admet-2088	303	13	2024	2024	NUM
admet-2088	303	14	)	)	PUNCT
admet-2088	303	15	107	107	NUM
admet-2088	303	16	-	-	SYM
admet-2088	303	17	150	150	NUM
admet-2088	303	18	nanomaterial	nanomaterial	NOUN
admet-2088	303	19	-	-	PUNCT
admet-2088	303	20	based	base	VERB
admet-2088	303	21	drug	drug	NOUN
admet-2088	303	22	delivery	delivery	NOUN
admet-2088	303	23	systems	system	NOUN
admet-2088	303	24	for	for	ADP
admet-2088	303	25	melanoma	melanoma	NOUN
admet-2088	303	26	therapy	therapy	NOUN
admet-2088	303	27	doi	doi	NOUN
admet-2088	303	28	:	:	PUNCT
admet-2088	303	29	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	303	30	119	119	NUM
admet-2088	303	31	cuo2nps	cuo2nps	NOUN
admet-2088	303	32	released	release	VERB
admet-2088	303	33	and	and	CCONJ
admet-2088	303	34	decomposed	decompose	VERB
admet-2088	303	35	to	to	PART
admet-2088	303	36	cu2	cu2	VERB
admet-2088	303	37	+	+	NOUN
admet-2088	303	38	and	and	CCONJ
admet-2088	303	39	h2o2	h2o2	NOUN
admet-2088	303	40	in	in	ADP
admet-2088	303	41	an	an	DET
admet-2088	303	42	acidic	acidic	ADJ
admet-2088	303	43	environment	environment	NOUN
admet-2088	303	44	prevailed	prevail	VERB
admet-2088	303	45	in	in	ADP
admet-2088	303	46	the	the	DET
admet-2088	303	47	cancerous	cancerous	ADJ
admet-2088	303	48	tissues	tissue	NOUN
admet-2088	303	49	.	.	PUNCT
admet-2088	304	1	thereafter	thereafter	ADV
admet-2088	304	2	,	,	PUNCT
admet-2088	304	3	cu2	cu2	NOUN
admet-2088	304	4	+	+	CCONJ
admet-2088	304	5	could	could	AUX
admet-2088	304	6	transform	transform	VERB
admet-2088	304	7	endogenous	endogenous	ADJ
admet-2088	304	8	h2o2	h2o2	NOUN
admet-2088	304	9	into	into	ADP
admet-2088	304	10	highly	highly	ADV
admet-2088	304	11	toxic	toxic	ADJ
admet-2088	304	12	oh	oh	INTJ
admet-2088	304	13	for	for	ADP
admet-2088	304	14	cdt	cdt	PROPN
admet-2088	304	15	,	,	PUNCT
admet-2088	304	16	further	far	ADV
admet-2088	304	17	enhanced	enhance	VERB
admet-2088	304	18	by	by	ADP
admet-2088	304	19	self	self	NOUN
admet-2088	304	20	-	-	PUNCT
admet-2088	304	21	supplied	supply	VERB
admet-2088	304	22	h2o2	h2o2	NOUN
admet-2088	304	23	.	.	NOUN
admet-2088	304	24	in	in	ADP
admet-2088	304	25	addition	addition	NOUN
admet-2088	304	26	,	,	PUNCT
admet-2088	304	27	cuo2nps	cuo2nps	PROPN
admet-2088	304	28	could	could	AUX
admet-2088	304	29	utilized	utilize	VERB
admet-2088	304	30	as	as	ADP
admet-2088	304	31	a	a	DET
admet-2088	304	32	glutathione	glutathione	NOUN
admet-2088	304	33	-	-	PUNCT
admet-2088	304	34	scavenging	scavenge	VERB
admet-2088	304	35	agent	agent	NOUN
admet-2088	304	36	for	for	ADP
admet-2088	304	37	boosting	boost	VERB
admet-2088	304	38	rosinduced	rosinduce	VERB
admet-2088	304	39	tumour	tumour	ADJ
admet-2088	304	40	cell	cell	NOUN
admet-2088	304	41	death	death	NOUN
admet-2088	304	42	.	.	PUNCT
admet-2088	305	1	this	this	PRON
admet-2088	305	2	was	be	AUX
admet-2088	305	3	confirmed	confirm	VERB
admet-2088	305	4	via	via	ADP
admet-2088	305	5	an	an	DET
admet-2088	305	6	in	in	ADV
admet-2088	305	7	-	-	PUNCT
admet-2088	305	8	vitro	vitro	X
admet-2088	305	9	study	study	NOUN
admet-2088	305	10	where	where	SCONJ
admet-2088	305	11	cuo2nps	cuo2nps	PROPN
admet-2088	305	12	encapsulated	encapsulate	VERB
admet-2088	305	13	microneedles	microneedle	NOUN
admet-2088	305	14	were	be	AUX
admet-2088	305	15	able	able	ADJ
admet-2088	305	16	to	to	PART
admet-2088	305	17	kill	kill	VERB
admet-2088	305	18	melanoma	melanoma	NOUN
admet-2088	305	19	cells	cell	NOUN
admet-2088	305	20	by	by	ADP
admet-2088	305	21	self	self	NOUN
admet-2088	305	22	-	-	PUNCT
admet-2088	305	23	enhanced	enhance	VERB
admet-2088	305	24	cdt	cdt	PROPN
admet-2088	305	25	.	.	PUNCT
admet-2088	306	1	being	be	AUX
admet-2088	306	2	a	a	DET
admet-2088	306	3	photosensitizer	photosensitizer	NOUN
admet-2088	306	4	,	,	PUNCT
admet-2088	306	5	cuo2nps	cuo2nps	PROPN
admet-2088	306	6	demonstrated	demonstrate	VERB
admet-2088	306	7	hyperthermia	hyperthermia	NOUN
admet-2088	306	8	in	in	ADP
admet-2088	306	9	the	the	DET
admet-2088	306	10	melanoma	melanoma	NOUN
admet-2088	306	11	area	area	NOUN
admet-2088	306	12	in	in	ADP
admet-2088	306	13	vivo	vivo	NOUN
admet-2088	306	14	under	under	ADP
admet-2088	306	15	the	the	DET
admet-2088	306	16	irradiation	irradiation	NOUN
admet-2088	306	17	of	of	ADP
admet-2088	306	18	nir	nir	NOUN
admet-2088	306	19	.	.	PUNCT
admet-2088	307	1	furthermore	furthermore	ADV
admet-2088	307	2	,	,	PUNCT
admet-2088	307	3	the	the	DET
admet-2088	307	4	microneedle	microneedle	NOUN
admet-2088	307	5	system	system	NOUN
admet-2088	307	6	showed	show	VERB
admet-2088	307	7	minimal	minimal	ADJ
admet-2088	307	8	side	side	NOUN
admet-2088	307	9	effects	effect	NOUN
admet-2088	307	10	in	in	ADP
admet-2088	307	11	vivo	vivo	NOUN
admet-2088	307	12	under	under	ADP
admet-2088	307	13	combination	combination	NOUN
admet-2088	307	14	therapy	therapy	NOUN
admet-2088	307	15	.	.	PUNCT
admet-2088	308	1	platinum	platinum	NOUN
admet-2088	308	2	nanoparticles	nanoparticle	NOUN
admet-2088	308	3	most	most	ADV
admet-2088	308	4	recently	recently	ADV
admet-2088	308	5	,	,	PUNCT
admet-2088	308	6	platinum	platinum	PROPN
admet-2088	308	7	nps	nps	PROPN
admet-2088	308	8	have	have	AUX
admet-2088	308	9	attracted	attract	VERB
admet-2088	308	10	the	the	DET
admet-2088	308	11	attention	attention	NOUN
admet-2088	308	12	of	of	ADP
admet-2088	308	13	many	many	ADJ
admet-2088	308	14	researchers	researcher	NOUN
admet-2088	308	15	because	because	SCONJ
admet-2088	308	16	of	of	ADP
admet-2088	308	17	their	their	PRON
admet-2088	308	18	unique	unique	ADJ
admet-2088	308	19	physico	physico	NOUN
admet-2088	308	20	-	-	PUNCT
admet-2088	308	21	chemical	chemical	NOUN
admet-2088	308	22	properties	property	NOUN
admet-2088	308	23	such	such	ADJ
admet-2088	308	24	as	as	ADP
admet-2088	308	25	ease	ease	NOUN
admet-2088	308	26	of	of	ADP
admet-2088	308	27	synthesis	synthesis	NOUN
admet-2088	308	28	,	,	PUNCT
admet-2088	308	29	small	small	ADJ
admet-2088	308	30	tuneable	tuneable	ADJ
admet-2088	308	31	size	size	NOUN
admet-2088	308	32	,	,	PUNCT
admet-2088	308	33	high	high	ADJ
admet-2088	308	34	surface	surface	NOUN
admet-2088	308	35	area	area	NOUN
admet-2088	308	36	for	for	ADP
admet-2088	308	37	functionalization	functionalization	NOUN
admet-2088	308	38	for	for	ADP
admet-2088	308	39	high	high	ADJ
admet-2088	308	40	drug	drug	NOUN
admet-2088	308	41	loading	loading	NOUN
admet-2088	308	42	,	,	PUNCT
admet-2088	308	43	and	and	CCONJ
admet-2088	308	44	platinum	platinum	PROPN
admet-2088	308	45	nps	nps	PROPN
admet-2088	308	46	and	and	CCONJ
admet-2088	308	47	platinum	platinum	NOUN
admet-2088	308	48	-	-	PUNCT
admet-2088	308	49	based	base	VERB
admet-2088	308	50	compounds	compound	NOUN
admet-2088	308	51	demonstrate	demonstrate	VERB
admet-2088	308	52	dual	dual	ADJ
admet-2088	308	53	functionality	functionality	NOUN
admet-2088	309	1	[	[	X
admet-2088	309	2	113	113	NUM
admet-2088	309	3	-	-	SYM
admet-2088	309	4	115	115	NUM
admet-2088	309	5	]	]	PUNCT
admet-2088	309	6	.	.	PUNCT
admet-2088	310	1	in	in	ADP
admet-2088	310	2	addition	addition	NOUN
admet-2088	310	3	,	,	PUNCT
admet-2088	310	4	platinum	platinum	NOUN
admet-2088	310	5	-	-	PUNCT
admet-2088	310	6	containing	contain	VERB
admet-2088	310	7	anticancer	anticancer	NOUN
admet-2088	310	8	drugs	drug	NOUN
admet-2088	310	9	such	such	ADJ
admet-2088	310	10	as	as	ADP
admet-2088	310	11	carboplatin	carboplatin	NOUN
admet-2088	310	12	,	,	PUNCT
admet-2088	310	13	cis	cis	NOUN
admet-2088	310	14	-	-	PUNCT
admet-2088	310	15	platin	platin	NOUN
admet-2088	310	16	and	and	CCONJ
admet-2088	310	17	oxaliplatin	oxaliplatin	NOUN
admet-2088	310	18	have	have	AUX
admet-2088	310	19	been	be	AUX
admet-2088	310	20	used	use	VERB
admet-2088	310	21	widely	widely	ADV
admet-2088	310	22	for	for	ADP
admet-2088	310	23	the	the	DET
admet-2088	310	24	treatment	treatment	NOUN
admet-2088	310	25	of	of	ADP
admet-2088	310	26	cancer	cancer	NOUN
admet-2088	310	27	[	[	X
admet-2088	310	28	116,117	116,117	NUM
admet-2088	310	29	]	]	PUNCT
admet-2088	310	30	.	.	PUNCT
admet-2088	311	1	further	far	ADV
admet-2088	311	2	,	,	PUNCT
admet-2088	311	3	it	it	PRON
admet-2088	311	4	has	have	VERB
admet-2088	311	5	a	a	DET
admet-2088	311	6	scavenging	scavenging	ADJ
admet-2088	311	7	effect	effect	NOUN
admet-2088	311	8	against	against	ADP
admet-2088	311	9	superoxide	superoxide	NOUN
admet-2088	311	10	and	and	CCONJ
admet-2088	311	11	h2o2	h2o2	NOUN
admet-2088	311	12	due	due	ADP
admet-2088	311	13	to	to	ADP
admet-2088	311	14	its	its	PRON
admet-2088	311	15	anti	anti	ADJ
admet-2088	311	16	-	-	ADJ
admet-2088	311	17	oxidant	oxidant	ADJ
admet-2088	311	18	properties	property	NOUN
admet-2088	311	19	.	.	PUNCT
admet-2088	312	1	the	the	DET
admet-2088	312	2	mechanisms	mechanism	NOUN
admet-2088	312	3	involved	involve	VERB
admet-2088	312	4	in	in	ADP
admet-2088	312	5	the	the	DET
admet-2088	312	6	anticancer	anticancer	NOUN
admet-2088	312	7	property	property	NOUN
admet-2088	312	8	of	of	ADP
admet-2088	312	9	platinum	platinum	NOUN
admet-2088	312	10	nps	nps	PROPN
admet-2088	312	11	include	include	VERB
admet-2088	312	12	the	the	DET
admet-2088	312	13	activation	activation	NOUN
admet-2088	312	14	against	against	ADP
admet-2088	312	15	signalling	signal	VERB
admet-2088	312	16	pathways	pathway	NOUN
admet-2088	312	17	p21	p21	NOUN
admet-2088	312	18	and	and	CCONJ
admet-2088	312	19	p53	p53	NOUN
admet-2088	312	20	,	,	PUNCT
admet-2088	312	21	resulting	result	VERB
admet-2088	312	22	in	in	ADP
admet-2088	312	23	apoptosis	apoptosis	NOUN
admet-2088	312	24	and	and	CCONJ
admet-2088	312	25	proliferating	proliferate	VERB
admet-2088	312	26	cell	cell	NOUN
admet-2088	312	27	nuclear	nuclear	ADJ
admet-2088	312	28	antigen	antigen	ADV
admet-2088	312	29	-	-	PUNCT
admet-2088	312	30	mediated	mediate	VERB
admet-2088	312	31	growth	growth	NOUN
admet-2088	312	32	arrest	arrest	NOUN
admet-2088	312	33	.	.	PUNCT
admet-2088	313	1	as	as	ADP
admet-2088	313	2	per	per	ADP
admet-2088	313	3	a	a	DET
admet-2088	313	4	recent	recent	ADJ
admet-2088	313	5	report	report	NOUN
admet-2088	313	6	,	,	PUNCT
admet-2088	313	7	silverplatinum	silverplatinum	PROPN
admet-2088	313	8	nps	nps	PROPN
admet-2088	313	9	have	have	VERB
admet-2088	313	10	huge	huge	ADJ
admet-2088	313	11	potential	potential	NOUN
admet-2088	313	12	against	against	ADP
admet-2088	313	13	melanoma	melanoma	NOUN
admet-2088	313	14	and	and	CCONJ
admet-2088	313	15	glioblastoma	glioblastoma	NOUN
admet-2088	313	16	cells	cell	NOUN
admet-2088	313	17	,	,	PUNCT
admet-2088	313	18	indicating	indicate	VERB
admet-2088	313	19	that	that	SCONJ
admet-2088	313	20	the	the	DET
admet-2088	313	21	nps	nps	PROPN
admet-2088	313	22	showed	show	VERB
admet-2088	313	23	cell	cell	NOUN
admet-2088	313	24	membrane	membrane	NOUN
admet-2088	313	25	interaction	interaction	NOUN
admet-2088	313	26	,	,	PUNCT
admet-2088	313	27	killing	kill	VERB
admet-2088	313	28	cancer	cancer	NOUN
admet-2088	313	29	cells	cell	NOUN
admet-2088	313	30	in	in	ADP
admet-2088	313	31	addition	addition	NOUN
admet-2088	313	32	to	to	ADP
admet-2088	313	33	cancer	cancer	NOUN
admet-2088	313	34	metastasis	metastasis	NOUN
admet-2088	313	35	[	[	X
admet-2088	313	36	2,118	2,118	NUM
admet-2088	313	37	]	]	PUNCT
admet-2088	313	38	.	.	PUNCT
admet-2088	314	1	mukherjee	mukherjee	PROPN
admet-2088	314	2	et	et	PROPN
admet-2088	314	3	al	al	PROPN
admet-2088	314	4	.	.	PUNCT
admet-2088	315	1	[	[	X
admet-2088	315	2	113	113	NUM
admet-2088	315	3	]	]	PUNCT
admet-2088	315	4	designed	design	VERB
admet-2088	315	5	and	and	CCONJ
admet-2088	315	6	developed	develop	VERB
admet-2088	315	7	peg	peg	NOUN
admet-2088	315	8	-	-	PUNCT
admet-2088	315	9	assisted	assist	VERB
admet-2088	315	10	/	/	SYM
admet-2088	315	11	stabilized	stabilize	VERB
admet-2088	315	12	colloidal	colloidal	NOUN
admet-2088	315	13	pt	pt	PROPN
admet-2088	315	14	-	-	PROPN
admet-2088	315	15	nps	nps	PROPN
admet-2088	315	16	employing	employ	VERB
admet-2088	315	17	the	the	DET
admet-2088	315	18	borohydride	borohydride	NOUN
admet-2088	315	19	reduction	reduction	NOUN
admet-2088	315	20	method	method	NOUN
admet-2088	315	21	.	.	PUNCT
admet-2088	316	1	this	this	DET
admet-2088	316	2	nanosystem	nanosystem	NOUN
admet-2088	316	3	showed	show	VERB
admet-2088	316	4	exceptional	exceptional	ADJ
admet-2088	316	5	stability	stability	NOUN
admet-2088	316	6	at	at	ADP
admet-2088	316	7	room	room	NOUN
admet-2088	316	8	temperature	temperature	NOUN
admet-2088	316	9	(	(	PUNCT
admet-2088	316	10	2	2	NUM
admet-2088	316	11	years	year	NOUN
admet-2088	316	12	)	)	PUNCT
admet-2088	316	13	and	and	CCONJ
admet-2088	316	14	serum	serum	NOUN
admet-2088	316	15	and	and	CCONJ
admet-2088	316	16	ph	ph	ADJ
admet-2088	316	17	7.4	7.4	NUM
admet-2088	316	18	phosphate	phosphate	NOUN
admet-2088	316	19	buffer	buffer	NOUN
admet-2088	316	20	(	(	PUNCT
admet-2088	316	21	one	one	NUM
admet-2088	316	22	week	week	NOUN
admet-2088	316	23	)	)	PUNCT
admet-2088	316	24	and	and	CCONJ
admet-2088	316	25	biocompatibility	biocompatibility	NOUN
admet-2088	316	26	in	in	ADP
admet-2088	316	27	vitro	vitro	X
admet-2088	316	28	(	(	PUNCT
admet-2088	316	29	normal	normal	ADJ
admet-2088	316	30	cell	cell	NOUN
admet-2088	316	31	line	line	NOUN
admet-2088	316	32	)	)	PUNCT
admet-2088	316	33	and	and	CCONJ
admet-2088	316	34	ex	ex	PRON
admet-2088	316	35	vivo	vivo	NOUN
admet-2088	316	36	(	(	PUNCT
admet-2088	316	37	chicken	chicken	NOUN
admet-2088	316	38	embryonic	embryonic	ADJ
admet-2088	316	39	model	model	NOUN
admet-2088	316	40	)	)	PUNCT
admet-2088	316	41	.	.	PUNCT
admet-2088	317	1	the	the	DET
admet-2088	317	2	resulting	result	VERB
admet-2088	317	3	nanosystem	nanosystem	NOUN
admet-2088	317	4	was	be	AUX
admet-2088	317	5	converted	convert	VERB
admet-2088	317	6	into	into	ADP
admet-2088	317	7	a	a	DET
admet-2088	317	8	drug	drug	NOUN
admet-2088	317	9	delivery	delivery	NOUN
admet-2088	317	10	system	system	NOUN
admet-2088	317	11	(	(	PUNCT
admet-2088	317	12	dds	dds	PROPN
admet-2088	317	13	)	)	PUNCT
admet-2088	317	14	by	by	ADP
admet-2088	317	15	conjugating	conjugate	VERB
admet-2088	317	16	with	with	ADP
admet-2088	317	17	doxorubicin	doxorubicin	PROPN
admet-2088	317	18	.	.	PUNCT
admet-2088	318	1	this	this	DET
admet-2088	318	2	dds	dds	PROPN
admet-2088	318	3	exhibited	exhibit	VERB
admet-2088	318	4	inhibition	inhibition	NOUN
admet-2088	318	5	of	of	ADP
admet-2088	318	6	cancer	cancer	NOUN
admet-2088	318	7	cell	cell	NOUN
admet-2088	318	8	(	(	PUNCT
admet-2088	318	9	b16f10	b16f10	NOUN
admet-2088	318	10	and	and	CCONJ
admet-2088	318	11	a549	a549	PROPN
admet-2088	318	12	)	)	PUNCT
admet-2088	318	13	proliferation	proliferation	NOUN
admet-2088	318	14	and	and	CCONJ
admet-2088	318	15	induced	induced	ADJ
admet-2088	318	16	apoptosis	apoptosis	NOUN
admet-2088	318	17	of	of	ADP
admet-2088	318	18	cancer	cancer	NOUN
admet-2088	318	19	cells	cell	NOUN
admet-2088	318	20	.	.	PUNCT
admet-2088	319	1	intraperitoneal	intraperitoneal	ADJ
admet-2088	319	2	administration	administration	NOUN
admet-2088	319	3	of	of	ADP
admet-2088	319	4	the	the	DET
admet-2088	319	5	dds	dds	PROPN
admet-2088	319	6	gave	give	VERB
admet-2088	319	7	a	a	DET
admet-2088	319	8	considerable	considerable	ADJ
admet-2088	319	9	reduction	reduction	NOUN
admet-2088	319	10	of	of	ADP
admet-2088	319	11	tumour	tumour	ADJ
admet-2088	319	12	growth	growth	NOUN
admet-2088	319	13	in	in	ADP
admet-2088	319	14	the	the	DET
admet-2088	319	15	subcutaneous	subcutaneous	ADJ
admet-2088	319	16	murine	murine	ADJ
admet-2088	319	17	melanoma	melanoma	NOUN
admet-2088	319	18	tumour	tumour	NOUN
admet-2088	319	19	model	model	NOUN
admet-2088	319	20	compared	compare	VERB
admet-2088	319	21	to	to	ADP
admet-2088	319	22	a	a	DET
admet-2088	319	23	control	control	NOUN
admet-2088	319	24	group	group	NOUN
admet-2088	319	25	with	with	ADP
admet-2088	319	26	a	a	DET
admet-2088	319	27	free	free	ADJ
admet-2088	319	28	drug	drug	NOUN
admet-2088	319	29	.	.	PUNCT
admet-2088	320	1	the	the	DET
admet-2088	320	2	mechanism	mechanism	NOUN
admet-2088	320	3	was	be	AUX
admet-2088	320	4	attributed	attribute	VERB
admet-2088	320	5	to	to	ADP
admet-2088	320	6	the	the	DET
admet-2088	320	7	possible	possible	ADJ
admet-2088	320	8	involvement	involvement	NOUN
admet-2088	320	9	of	of	ADP
admet-2088	320	10	the	the	DET
admet-2088	320	11	p53	p53	NOUN
admet-2088	320	12	-	-	PUNCT
admet-2088	320	13	mediated	mediate	VERB
admet-2088	320	14	apoptotic	apoptotic	ADJ
admet-2088	320	15	signalling	signal	VERB
admet-2088	320	16	pathway	pathway	NOUN
admet-2088	320	17	and	and	CCONJ
admet-2088	320	18	downregulation	downregulation	NOUN
admet-2088	320	19	of	of	ADP
admet-2088	320	20	sox2	sox2	NOUN
admet-2088	320	21	and	and	CCONJ
admet-2088	320	22	ki-67	ki-67	ADJ
admet-2088	320	23	proliferation	proliferation	NOUN
admet-2088	320	24	markers	marker	NOUN
admet-2088	320	25	.	.	PUNCT
admet-2088	321	1	salehi	salehi	PROPN
admet-2088	321	2	et	et	PROPN
admet-2088	321	3	al	al	PROPN
admet-2088	321	4	.	.	PUNCT
admet-2088	322	1	[	[	X
admet-2088	322	2	119	119	NUM
admet-2088	322	3	]	]	PUNCT
admet-2088	322	4	developed	develop	VERB
admet-2088	322	5	platinum	platinum	NOUN
admet-2088	322	6	mesoporous	mesoporous	ADJ
admet-2088	322	7	nps	nps	PROPN
admet-2088	322	8	with	with	ADP
admet-2088	322	9	particle	particle	NOUN
admet-2088	322	10	size	size	NOUN
admet-2088	322	11	and	and	CCONJ
admet-2088	322	12	pore	pore	ADJ
admet-2088	322	13	size	size	NOUN
admet-2088	322	14	<	<	PROPN
admet-2088	322	15	11	11	NUM
admet-2088	322	16	nm	nm	NOUN
admet-2088	322	17	and	and	CCONJ
admet-2088	322	18	5	5	NUM
admet-2088	322	19	nm	nm	NOUN
admet-2088	322	20	,	,	PUNCT
admet-2088	322	21	respectively	respectively	ADV
admet-2088	322	22	,	,	PUNCT
admet-2088	322	23	and	and	CCONJ
admet-2088	322	24	evaluated	evaluate	VERB
admet-2088	322	25	their	their	PRON
admet-2088	322	26	toxicity	toxicity	NOUN
admet-2088	322	27	against	against	ADP
admet-2088	322	28	melanoma	melanoma	NOUN
admet-2088	322	29	cell	cell	NOUN
admet-2088	322	30	line	line	NOUN
admet-2088	322	31	c540	c540	PROPN
admet-2088	322	32	alone	alone	ADJ
admet-2088	322	33	or	or	CCONJ
admet-2088	322	34	combined	combine	VERB
admet-2088	322	35	with	with	ADP
admet-2088	322	36	laser	laser	NOUN
admet-2088	322	37	radiation	radiation	NOUN
admet-2088	322	38	and	and	CCONJ
admet-2088	322	39	x	x	NOUN
admet-2088	322	40	-	-	NOUN
admet-2088	322	41	ray	ray	NOUN
admet-2088	322	42	irradiation	irradiation	NOUN
admet-2088	322	43	.	.	PUNCT
admet-2088	323	1	when	when	SCONJ
admet-2088	323	2	used	use	VERB
admet-2088	323	3	alone	alone	ADV
admet-2088	323	4	,	,	PUNCT
admet-2088	323	5	these	these	DET
admet-2088	323	6	nps	nps	PROPN
admet-2088	323	7	showed	show	VERB
admet-2088	323	8	low	low	ADJ
admet-2088	323	9	toxicity	toxicity	NOUN
admet-2088	323	10	against	against	ADP
admet-2088	323	11	cell	cell	NOUN
admet-2088	323	12	lines	line	NOUN
admet-2088	323	13	as	as	ADV
admet-2088	323	14	well	well	ADV
admet-2088	323	15	as	as	ADP
admet-2088	323	16	laser	laser	NOUN
admet-2088	323	17	radiation	radiation	NOUN
admet-2088	323	18	(	(	PUNCT
admet-2088	323	19	no	no	DET
admet-2088	323	20	toxicity	toxicity	NOUN
admet-2088	323	21	)	)	PUNCT
admet-2088	323	22	and	and	CCONJ
admet-2088	323	23	x	x	X
admet-2088	323	24	-	-	NOUN
admet-2088	323	25	ray	ray	NOUN
admet-2088	323	26	irradiation	irradiation	NOUN
admet-2088	323	27	(	(	PUNCT
admet-2088	323	28	limited	limited	ADJ
admet-2088	323	29	toxicity	toxicity	NOUN
admet-2088	323	30	)	)	PUNCT
admet-2088	323	31	.	.	PUNCT
admet-2088	324	1	however	however	ADV
admet-2088	324	2	,	,	PUNCT
admet-2088	324	3	the	the	DET
admet-2088	324	4	combined	combined	ADJ
admet-2088	324	5	therapy	therapy	NOUN
admet-2088	324	6	(	(	PUNCT
admet-2088	324	7	laser	laser	NOUN
admet-2088	324	8	radiation	radiation	NOUN
admet-2088	324	9	followed	follow	VERB
admet-2088	324	10	by	by	ADP
admet-2088	324	11	x	x	NOUN
admet-2088	324	12	-	-	NOUN
admet-2088	324	13	ray	ray	NOUN
admet-2088	324	14	irradiation	irradiation	NOUN
admet-2088	324	15	)	)	PUNCT
admet-2088	324	16	demonstrated	demonstrate	VERB
admet-2088	324	17	deep	deep	ADJ
admet-2088	324	18	cell	cell	NOUN
admet-2088	324	19	killing	kill	VERB
admet-2088	324	20	with	with	ADP
admet-2088	324	21	a	a	DET
admet-2088	324	22	very	very	ADV
admet-2088	324	23	low	low	ADJ
admet-2088	324	24	melanoma	melanoma	NOUN
admet-2088	324	25	cell	cell	NOUN
admet-2088	324	26	viability	viability	NOUN
admet-2088	324	27	(	(	PUNCT
admet-2088	324	28	1	1	PROPN
admet-2088	324	29	%	%	NOUN
admet-2088	324	30	)	)	PUNCT
admet-2088	324	31	,	,	PUNCT
admet-2088	324	32	indicating	indicate	VERB
admet-2088	324	33	a	a	DET
admet-2088	324	34	synergistic	synergistic	ADJ
admet-2088	324	35	activity	activity	NOUN
admet-2088	324	36	.	.	PUNCT
admet-2088	325	1	in	in	ADP
admet-2088	325	2	addition	addition	NOUN
admet-2088	325	3	,	,	PUNCT
admet-2088	325	4	these	these	DET
admet-2088	325	5	nps	nps	PROPN
admet-2088	325	6	acted	act	VERB
admet-2088	325	7	as	as	ADP
admet-2088	325	8	potential	potential	ADJ
admet-2088	325	9	photosensitizers	photosensitizer	NOUN
admet-2088	325	10	and	and	CCONJ
admet-2088	325	11	radiosensitizers	radiosensitizer	NOUN
admet-2088	325	12	.	.	PUNCT
admet-2088	326	1	the	the	DET
admet-2088	326	2	mechanism	mechanism	NOUN
admet-2088	326	3	was	be	AUX
admet-2088	326	4	attributed	attribute	VERB
admet-2088	326	5	to	to	ADP
admet-2088	326	6	the	the	DET
admet-2088	326	7	significant	significant	ADJ
admet-2088	326	8	generation	generation	NOUN
admet-2088	326	9	of	of	ADP
admet-2088	326	10	ros	ros	PROPN
admet-2088	326	11	upon	upon	SCONJ
admet-2088	326	12	combined	combined	ADJ
admet-2088	326	13	exposure	exposure	NOUN
admet-2088	326	14	of	of	ADP
admet-2088	326	15	the	the	DET
admet-2088	326	16	cell	cell	NOUN
admet-2088	326	17	line	line	NOUN
admet-2088	326	18	to	to	PART
admet-2088	326	19	laser	laser	VERB
admet-2088	326	20	and	and	CCONJ
admet-2088	326	21	x	x	NOUN
admet-2088	326	22	-	-	NOUN
admet-2088	326	23	ray	ray	NOUN
admet-2088	326	24	.	.	PUNCT
admet-2088	327	1	silica	silica	NOUN
admet-2088	327	2	nanoparticles	nanoparticle	NOUN
admet-2088	327	3	silica	silica	NOUN
admet-2088	327	4	or	or	CCONJ
admet-2088	327	5	silicon	silicon	PROPN
admet-2088	327	6	nps	nps	PROPN
admet-2088	327	7	were	be	AUX
admet-2088	327	8	invented	invent	VERB
admet-2088	327	9	in	in	ADP
admet-2088	327	10	the	the	DET
admet-2088	327	11	1960s	1960	NOUN
admet-2088	327	12	and	and	CCONJ
admet-2088	327	13	widely	widely	ADV
admet-2088	327	14	used	use	VERB
admet-2088	327	15	as	as	ADP
admet-2088	327	16	catalysts	catalyst	NOUN
admet-2088	327	17	because	because	SCONJ
admet-2088	327	18	of	of	ADP
admet-2088	327	19	their	their	PRON
admet-2088	327	20	large	large	ADJ
admet-2088	327	21	surfaceto	surfaceto	NOUN
admet-2088	327	22	-	-	PUNCT
admet-2088	327	23	volume	volume	NOUN
admet-2088	327	24	ratios	ratio	NOUN
admet-2088	327	25	.	.	PUNCT
admet-2088	328	1	silica	silica	PROPN
admet-2088	328	2	nps	nps	PROPN
admet-2088	328	3	are	be	AUX
admet-2088	328	4	one	one	NUM
admet-2088	328	5	of	of	ADP
admet-2088	328	6	the	the	DET
admet-2088	328	7	most	most	ADV
admet-2088	328	8	popular	popular	ADJ
admet-2088	328	9	and	and	CCONJ
admet-2088	328	10	common	common	ADJ
admet-2088	328	11	inorganic	inorganic	ADJ
admet-2088	328	12	nps	nps	PROPN
admet-2088	328	13	to	to	PART
admet-2088	328	14	be	be	AUX
admet-2088	328	15	used	use	VERB
admet-2088	328	16	for	for	ADP
admet-2088	328	17	special	special	ADJ
admet-2088	328	18	biological	biological	ADJ
admet-2088	328	19	applications	application	NOUN
admet-2088	328	20	due	due	ADP
admet-2088	328	21	to	to	ADP
admet-2088	328	22	their	their	PRON
admet-2088	328	23	suitable	suitable	ADJ
admet-2088	328	24	physical	physical	ADJ
admet-2088	328	25	parameters	parameter	NOUN
admet-2088	328	26	such	such	ADJ
admet-2088	328	27	as	as	ADP
admet-2088	328	28	size	size	NOUN
admet-2088	328	29	,	,	PUNCT
admet-2088	328	30	shape	shape	NOUN
admet-2088	328	31	,	,	PUNCT
admet-2088	328	32	tuneable	tuneable	ADJ
admet-2088	328	33	pore	pore	ADJ
admet-2088	328	34	size	size	NOUN
admet-2088	328	35	(	(	PUNCT
admet-2088	328	36	2	2	NUM
admet-2088	328	37	to	to	PART
admet-2088	328	38	10	10	NUM
admet-2088	328	39	nm	nm	NOUN
admet-2088	328	40	)	)	PUNCT
admet-2088	328	41	for	for	ADP
admet-2088	328	42	drug	drug	NOUN
admet-2088	328	43	encapsulation	encapsulation	NOUN
admet-2088	328	44	[	[	X
admet-2088	328	45	73	73	NUM
admet-2088	328	46	]	]	PUNCT
admet-2088	328	47	,	,	PUNCT
admet-2088	328	48	ordered	order	VERB
admet-2088	328	49	pore	pore	ADJ
admet-2088	328	50	structure	structure	NOUN
admet-2088	328	51	,	,	PUNCT
admet-2088	328	52	ease	ease	NOUN
admet-2088	328	53	of	of	ADP
admet-2088	328	54	camouflage	camouflage	NOUN
admet-2088	328	55	by	by	ADP
admet-2088	328	56	chemical	chemical	ADJ
admet-2088	328	57	conjugation	conjugation	NOUN
admet-2088	328	58	with	with	ADP
admet-2088	328	59	biocompatible	biocompatible	NOUN
admet-2088	328	60	,	,	PUNCT
admet-2088	328	61	targeting	target	VERB
admet-2088	328	62	and	and	CCONJ
admet-2088	328	63	imaging	imaging	NOUN
admet-2088	328	64	ligands	ligand	NOUN
admet-2088	328	65	[	[	X
admet-2088	328	66	120	120	NUM
admet-2088	328	67	]	]	PUNCT
admet-2088	328	68	.	.	PUNCT
admet-2088	329	1	the	the	DET
admet-2088	329	2	applicability	applicability	NOUN
admet-2088	329	3	of	of	ADP
admet-2088	329	4	silica	silica	PROPN
admet-2088	329	5	nps	nps	PROPN
admet-2088	329	6	increased	increase	VERB
admet-2088	329	7	manifold	manifold	ADJ
admet-2088	329	8	due	due	ADP
admet-2088	329	9	to	to	ADP
admet-2088	329	10	the	the	DET
admet-2088	329	11	synthesis	synthesis	NOUN
admet-2088	329	12	of	of	ADP
admet-2088	329	13	mesoporous	mesoporous	ADJ
admet-2088	329	14	silica	silica	NOUN
admet-2088	329	15	nps	nps	PROPN
admet-2088	329	16	in	in	ADP
admet-2088	329	17	the	the	DET
admet-2088	329	18	1990s	1990	NOUN
admet-2088	329	19	[	[	X
admet-2088	329	20	72	72	NUM
admet-2088	329	21	]	]	X
admet-2088	329	22	,	,	PUNCT
admet-2088	329	23	which	which	PRON
admet-2088	329	24	have	have	VERB
admet-2088	329	25	superior	superior	ADJ
admet-2088	329	26	quality	quality	NOUN
admet-2088	329	27	than	than	ADP
admet-2088	329	28	other	other	ADJ
admet-2088	329	29	inorganic	inorganic	ADJ
admet-2088	329	30	nms	nms	NOUN
admet-2088	329	31	in	in	ADP
admet-2088	329	32	terms	term	NOUN
admet-2088	329	33	of	of	ADP
admet-2088	329	34	their	their	PRON
admet-2088	329	35	biocompatibility	biocompatibility	NOUN
admet-2088	329	36	,	,	PUNCT
admet-2088	329	37	degradability	degradability	NOUN
admet-2088	329	38	and	and	CCONJ
admet-2088	329	39	drug	drug	NOUN
admet-2088	329	40	release	release	NOUN
admet-2088	329	41	rates	rate	NOUN
admet-2088	329	42	.	.	PUNCT
admet-2088	330	1	mesoporous	mesoporous	ADJ
admet-2088	330	2	silica	silica	PROPN
admet-2088	330	3	nps	nps	PROPN
admet-2088	330	4	provide	provide	VERB
admet-2088	330	5	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	330	6	m.	m.	NOUN
admet-2088	330	7	kulkarni	kulkarni	PROPN
admet-2088	330	8	et	et	PROPN
admet-2088	330	9	al	al	PROPN
admet-2088	330	10	.	.	PROPN
admet-2088	330	11	admet	admet	PROPN
admet-2088	330	12	&	&	CCONJ
admet-2088	330	13	dmpk	dmpk	PROPN
admet-2088	330	14	12(1	12(1	PROPN
admet-2088	330	15	)	)	PUNCT
admet-2088	330	16	(	(	PUNCT
admet-2088	330	17	2024	2024	NUM
admet-2088	330	18	)	)	PUNCT
admet-2088	330	19	107	107	NUM
admet-2088	330	20	-	-	SYM
admet-2088	330	21	150	150	NUM
admet-2088	330	22	120	120	NUM
admet-2088	330	23	an	an	DET
admet-2088	330	24	effective	effective	ADJ
admet-2088	330	25	nanocarrier	nanocarrier	NOUN
admet-2088	330	26	dds	dds	PROPN
admet-2088	330	27	for	for	ADP
admet-2088	330	28	the	the	DET
admet-2088	330	29	oral	oral	ADJ
admet-2088	330	30	route	route	NOUN
admet-2088	330	31	due	due	ADP
admet-2088	330	32	to	to	ADP
admet-2088	330	33	their	their	PRON
admet-2088	330	34	hydrophilic	hydrophilic	ADJ
admet-2088	330	35	surface	surface	NOUN
admet-2088	330	36	leading	lead	VERB
admet-2088	330	37	to	to	ADP
admet-2088	330	38	higher	high	ADJ
admet-2088	330	39	affinity	affinity	NOUN
admet-2088	330	40	for	for	ADP
admet-2088	330	41	the	the	DET
admet-2088	330	42	head	head	NOUN
admet-2088	330	43	groups	group	NOUN
admet-2088	330	44	of	of	ADP
admet-2088	330	45	different	different	ADJ
admet-2088	330	46	phospholipids	phospholipid	NOUN
admet-2088	330	47	and	and	CCONJ
admet-2088	330	48	can	can	AUX
admet-2088	330	49	be	be	AUX
admet-2088	330	50	modulated	modulate	VERB
admet-2088	330	51	employing	employ	VERB
admet-2088	330	52	various	various	ADJ
admet-2088	330	53	surfactant	surfactant	ADJ
admet-2088	330	54	concentrations	concentration	NOUN
admet-2088	330	55	,	,	PUNCT
admet-2088	330	56	templates	template	NOUN
admet-2088	330	57	ph	ph	NOUN
admet-2088	330	58	and	and	CCONJ
admet-2088	330	59	solvents	solvent	NOUN
admet-2088	330	60	during	during	ADP
admet-2088	330	61	their	their	PRON
admet-2088	330	62	synthesis	synthesis	NOUN
admet-2088	330	63	,	,	PUNCT
admet-2088	330	64	high	high	ADJ
admet-2088	330	65	drug	drug	NOUN
admet-2088	330	66	loading	loading	NOUN
admet-2088	330	67	capacity	capacity	NOUN
admet-2088	330	68	,	,	PUNCT
admet-2088	330	69	high	high	ADJ
admet-2088	330	70	cellular	cellular	ADJ
admet-2088	330	71	penetrations	penetration	NOUN
admet-2088	330	72	,	,	PUNCT
admet-2088	330	73	protection	protection	NOUN
admet-2088	330	74	from	from	ADP
admet-2088	330	75	the	the	DET
admet-2088	330	76	acidic	acidic	ADJ
admet-2088	330	77	environment	environment	NOUN
admet-2088	330	78	of	of	ADP
admet-2088	330	79	the	the	DET
admet-2088	330	80	stomach	stomach	NOUN
admet-2088	330	81	and	and	CCONJ
admet-2088	330	82	most	most	ADV
admet-2088	330	83	important	important	ADJ
admet-2088	330	84	of	of	ADP
admet-2088	330	85	all	all	PRON
admet-2088	330	86	is	be	AUX
admet-2088	330	87	the	the	DET
admet-2088	330	88	controlled	control	VERB
admet-2088	330	89	release	release	NOUN
admet-2088	330	90	with	with	ADP
admet-2088	330	91	targeted	target	VERB
admet-2088	330	92	delivery	delivery	NOUN
admet-2088	331	1	[	[	X
admet-2088	331	2	5	5	NUM
admet-2088	331	3	]	]	PUNCT
admet-2088	331	4	.	.	PUNCT
admet-2088	332	1	it	it	PRON
admet-2088	332	2	was	be	AUX
admet-2088	332	3	reported	report	VERB
admet-2088	332	4	that	that	SCONJ
admet-2088	332	5	mesoporous	mesoporous	ADJ
admet-2088	332	6	silica	silica	NOUN
admet-2088	332	7	nps	nps	PROPN
admet-2088	332	8	have	have	AUX
admet-2088	332	9	been	be	AUX
admet-2088	332	10	used	use	VERB
admet-2088	332	11	as	as	ADP
admet-2088	332	12	gatekeepers	gatekeeper	NOUN
admet-2088	332	13	for	for	ADP
admet-2088	332	14	controlled	control	VERB
admet-2088	332	15	drug	drug	NOUN
admet-2088	332	16	release	release	NOUN
admet-2088	333	1	[	[	X
admet-2088	333	2	121,122	121,122	NUM
admet-2088	333	3	]	]	PUNCT
admet-2088	333	4	,	,	PUNCT
admet-2088	334	1	and	and	CCONJ
admet-2088	334	2	found	find	VERB
admet-2088	334	3	to	to	PART
admet-2088	334	4	be	be	AUX
admet-2088	334	5	endocytosed	endocytose	VERB
admet-2088	334	6	by	by	ADP
admet-2088	334	7	tumour	tumour	NOUN
admet-2088	334	8	cells	cell	NOUN
admet-2088	334	9	,	,	PUNCT
admet-2088	334	10	macrophages	macrophage	NOUN
admet-2088	334	11	as	as	ADV
admet-2088	334	12	well	well	ADV
admet-2088	334	13	and	and	CCONJ
admet-2088	334	14	non	non	ADJ
admet-2088	334	15	-	-	ADJ
admet-2088	334	16	cancer	cancer	ADJ
admet-2088	334	17	cells	cell	NOUN
admet-2088	334	18	[	[	X
admet-2088	334	19	123	123	NUM
admet-2088	334	20	]	]	PUNCT
admet-2088	334	21	.	.	PUNCT
admet-2088	335	1	the	the	DET
admet-2088	335	2	importance	importance	NOUN
admet-2088	335	3	of	of	ADP
admet-2088	335	4	plant	plant	NOUN
admet-2088	335	5	-	-	PUNCT
admet-2088	335	6	derived	derive	VERB
admet-2088	335	7	compounds	compound	NOUN
admet-2088	335	8	has	have	AUX
admet-2088	335	9	been	be	AUX
admet-2088	335	10	recognized	recognize	VERB
admet-2088	335	11	as	as	ADP
admet-2088	335	12	potential	potential	ADJ
admet-2088	335	13	agents	agent	NOUN
admet-2088	335	14	for	for	ADP
admet-2088	335	15	the	the	DET
admet-2088	335	16	prevention	prevention	NOUN
admet-2088	335	17	and	and	CCONJ
admet-2088	335	18	treatment	treatment	NOUN
admet-2088	335	19	of	of	ADP
admet-2088	335	20	different	different	ADJ
admet-2088	335	21	types	type	NOUN
admet-2088	335	22	of	of	ADP
admet-2088	335	23	cancers	cancer	NOUN
admet-2088	335	24	,	,	PUNCT
admet-2088	335	25	including	include	VERB
admet-2088	335	26	melanoma	melanoma	NOUN
admet-2088	335	27	.	.	PUNCT
admet-2088	336	1	among	among	ADP
admet-2088	336	2	many	many	ADJ
admet-2088	336	3	plant	plant	NOUN
admet-2088	336	4	compounds	compound	NOUN
admet-2088	336	5	,	,	PUNCT
admet-2088	336	6	curcumin	curcumin	NOUN
admet-2088	336	7	has	have	AUX
admet-2088	336	8	been	be	AUX
admet-2088	336	9	proven	prove	VERB
admet-2088	336	10	to	to	PART
admet-2088	336	11	be	be	AUX
admet-2088	336	12	a	a	DET
admet-2088	336	13	promising	promising	ADJ
admet-2088	336	14	anticancer	anticancer	NOUN
admet-2088	336	15	compound	compound	NOUN
admet-2088	337	1	[	[	X
admet-2088	337	2	124	124	NUM
admet-2088	337	3	]	]	PUNCT
admet-2088	337	4	.	.	PUNCT
admet-2088	338	1	therefore	therefore	ADV
admet-2088	338	2	,	,	PUNCT
admet-2088	338	3	ghazaeian	ghazaeian	PROPN
admet-2088	338	4	et	et	PROPN
admet-2088	338	5	al	al	PROPN
admet-2088	338	6	.	.	PUNCT
admet-2088	339	1	[	[	X
admet-2088	339	2	125	125	NUM
admet-2088	339	3	]	]	PUNCT
admet-2088	339	4	fabricated	fabricate	VERB
admet-2088	339	5	curcumin	curcumin	NOUN
admet-2088	339	6	-	-	PUNCT
admet-2088	339	7	silica	silica	NOUN
admet-2088	339	8	nanocomplex	nanocomplex	NOUN
admet-2088	339	9	as	as	ADP
admet-2088	339	10	a	a	DET
admet-2088	339	11	photosensitizer	photosensitizer	NOUN
admet-2088	339	12	for	for	ADP
admet-2088	339	13	pdt	pdt	NOUN
admet-2088	339	14	in	in	ADP
admet-2088	339	15	the	the	DET
admet-2088	339	16	treatment	treatment	NOUN
admet-2088	339	17	of	of	ADP
admet-2088	339	18	melanoma	melanoma	NOUN
admet-2088	339	19	.	.	PUNCT
admet-2088	340	1	the	the	DET
admet-2088	340	2	curcumin	curcumin	NOUN
admet-2088	340	3	loading	loading	NOUN
admet-2088	340	4	onto	onto	ADP
admet-2088	340	5	silica	silica	NOUN
admet-2088	340	6	was	be	AUX
admet-2088	340	7	found	find	VERB
admet-2088	340	8	to	to	PART
admet-2088	340	9	be	be	AUX
admet-2088	340	10	successful	successful	ADJ
admet-2088	340	11	,	,	PUNCT
admet-2088	340	12	leading	lead	VERB
admet-2088	340	13	to	to	ADP
admet-2088	340	14	the	the	DET
admet-2088	340	15	enhancement	enhancement	NOUN
admet-2088	340	16	of	of	ADP
admet-2088	340	17	curcumin	curcumin	NOUN
admet-2088	340	18	solubility	solubility	NOUN
admet-2088	340	19	in	in	ADP
admet-2088	340	20	water	water	NOUN
admet-2088	340	21	.	.	PUNCT
admet-2088	341	1	the	the	DET
admet-2088	341	2	nanocomplex	nanocomplex	NOUN
admet-2088	341	3	showed	show	VERB
admet-2088	341	4	interaction	interaction	NOUN
admet-2088	341	5	with	with	ADP
admet-2088	341	6	dna	dna	NOUN
admet-2088	341	7	but	but	CCONJ
admet-2088	341	8	no	no	DET
admet-2088	341	9	interaction	interaction	NOUN
admet-2088	341	10	with	with	ADP
admet-2088	341	11	haemoglobin	haemoglobin	NOUN
admet-2088	341	12	.	.	PUNCT
admet-2088	342	1	the	the	DET
admet-2088	342	2	investigation	investigation	NOUN
admet-2088	342	3	of	of	ADP
admet-2088	342	4	curcumin	curcumin	NOUN
admet-2088	342	5	nanocomplex	nanocomplex	PROPN
admet-2088	342	6	and	and	CCONJ
admet-2088	342	7	pdt	pdt	PROPN
admet-2088	342	8	on	on	ADP
admet-2088	342	9	human	human	ADJ
admet-2088	342	10	melanoma	melanoma	NOUN
admet-2088	342	11	cancer	cancer	NOUN
admet-2088	342	12	cells	cell	NOUN
admet-2088	342	13	(	(	PUNCT
admet-2088	342	14	a375	a375	PROPN
admet-2088	342	15	)	)	PUNCT
admet-2088	342	16	and	and	CCONJ
admet-2088	342	17	human	human	ADJ
admet-2088	342	18	fibroblast	fibroblast	ADJ
admet-2088	342	19	cells	cell	NOUN
admet-2088	342	20	demonstrated	demonstrate	VERB
admet-2088	342	21	higher	high	ADJ
admet-2088	342	22	cancerous	cancerous	ADJ
admet-2088	342	23	cell	cell	NOUN
admet-2088	342	24	death	death	NOUN
admet-2088	342	25	compared	compare	VERB
admet-2088	342	26	to	to	ADP
admet-2088	342	27	free	free	ADJ
admet-2088	342	28	curcumin	curcumin	NOUN
admet-2088	342	29	.	.	PUNCT
admet-2088	343	1	the	the	DET
admet-2088	343	2	mechanism	mechanism	NOUN
admet-2088	343	3	was	be	AUX
admet-2088	343	4	attributed	attribute	VERB
admet-2088	343	5	to	to	ADP
admet-2088	343	6	the	the	DET
admet-2088	343	7	formation	formation	NOUN
admet-2088	343	8	of	of	ADP
admet-2088	343	9	ros	ros	PROPN
admet-2088	343	10	,	,	PUNCT
admet-2088	343	11	which	which	PRON
admet-2088	343	12	contributes	contribute	VERB
admet-2088	343	13	to	to	ADP
admet-2088	343	14	cell	cell	NOUN
admet-2088	343	15	death	death	NOUN
admet-2088	344	1	[	[	X
admet-2088	344	2	125	125	NUM
admet-2088	344	3	]	]	PUNCT
admet-2088	344	4	.	.	PUNCT
admet-2088	345	1	further	far	ADV
admet-2088	345	2	,	,	PUNCT
admet-2088	345	3	rizzi	rizzi	PROPN
admet-2088	345	4	et	et	PROPN
admet-2088	345	5	al	al	PROPN
admet-2088	345	6	.	.	PUNCT
admet-2088	346	1	[	[	X
admet-2088	346	2	28	28	NUM
admet-2088	346	3	]	]	PUNCT
admet-2088	346	4	employed	employ	VERB
admet-2088	346	5	the	the	DET
admet-2088	346	6	same	same	ADJ
admet-2088	346	7	mesoporous	mesoporous	ADJ
admet-2088	346	8	silica	silica	NOUN
admet-2088	346	9	nps	nps	PROPN
admet-2088	346	10	(	(	PUNCT
admet-2088	346	11	m	m	PROPN
admet-2088	346	12	sinps	sinps	ADJ
admet-2088	346	13	)	)	PUNCT
admet-2088	346	14	to	to	PART
admet-2088	346	15	conjugate	conjugate	VERB
admet-2088	346	16	with	with	ADP
admet-2088	346	17	second	second	ADJ
admet-2088	346	18	-	-	PUNCT
admet-2088	346	19	generation	generation	NOUN
admet-2088	346	20	photosensitizer	photosensitizer	NOUN
admet-2088	346	21	verteporfin	verteporfin	NOUN
admet-2088	346	22	to	to	PART
admet-2088	346	23	form	form	VERB
admet-2088	346	24	nanocomplex	nanocomplex	NOUN
admet-2088	346	25	(	(	PUNCT
admet-2088	346	26	ver	ver	NOUN
admet-2088	346	27	-	-	PUNCT
admet-2088	346	28	m	m	NOUN
admet-2088	346	29	sinps	sinps	ADJ
admet-2088	346	30	)	)	PUNCT
admet-2088	346	31	.	.	PUNCT
admet-2088	347	1	the	the	DET
admet-2088	347	2	formed	form	VERB
admet-2088	347	3	nanocomplex	nanocomplex	NOUN
admet-2088	347	4	was	be	AUX
admet-2088	347	5	tested	test	VERB
admet-2088	347	6	in	in	ADP
admet-2088	347	7	pdt	pdt	PROPN
admet-2088	347	8	therapy	therapy	NOUN
admet-2088	347	9	against	against	ADP
admet-2088	347	10	melanoma	melanoma	NOUN
admet-2088	347	11	and	and	CCONJ
admet-2088	347	12	the	the	DET
admet-2088	347	13	results	result	NOUN
admet-2088	347	14	showed	show	VERB
admet-2088	347	15	that	that	SCONJ
admet-2088	347	16	the	the	DET
admet-2088	347	17	nanocomplex	nanocomplex	NOUN
admet-2088	347	18	selectively	selectively	ADV
admet-2088	347	19	reduced	reduce	VERB
admet-2088	347	20	cancer	cancer	NOUN
admet-2088	347	21	cell	cell	NOUN
admet-2088	347	22	proliferation	proliferation	NOUN
admet-2088	347	23	in	in	ADP
admet-2088	347	24	highly	highly	ADV
admet-2088	347	25	invasive	invasive	ADJ
admet-2088	347	26	melanoma	melanoma	NOUN
admet-2088	347	27	cell	cell	NOUN
admet-2088	347	28	line	line	NOUN
admet-2088	347	29	(	(	PUNCT
admet-2088	347	30	skmel-28	skmel-28	PROPN
admet-2088	347	31	)	)	PUNCT
admet-2088	347	32	without	without	ADP
admet-2088	347	33	affecting	affect	VERB
admet-2088	347	34	the	the	DET
admet-2088	347	35	proliferation	proliferation	NOUN
admet-2088	347	36	of	of	ADP
admet-2088	347	37	either	either	CCONJ
admet-2088	347	38	a	a	DET
admet-2088	347	39	normal	normal	ADJ
admet-2088	347	40	human	human	ADJ
admet-2088	347	41	keratinocyte	keratinocyte	NOUN
admet-2088	347	42	cell	cell	NOUN
admet-2088	347	43	line	line	NOUN
admet-2088	347	44	(	(	PUNCT
admet-2088	347	45	hacat	hacat	NUM
admet-2088	347	46	)	)	PUNCT
admet-2088	347	47	or	or	CCONJ
admet-2088	347	48	low	low	ADJ
admet-2088	347	49	metastatic	metastatic	ADJ
admet-2088	347	50	melanoma	melanoma	NOUN
admet-2088	347	51	cell	cell	NOUN
admet-2088	347	52	line	line	NOUN
admet-2088	347	53	(	(	PUNCT
admet-2088	347	54	a375p	a375p	NOUN
admet-2088	347	55	)	)	PUNCT
admet-2088	347	56	,	,	PUNCT
admet-2088	347	57	thus	thus	ADV
admet-2088	347	58	assuring	assure	VERB
admet-2088	347	59	lower	low	ADJ
admet-2088	347	60	side	side	NOUN
admet-2088	347	61	effects	effect	NOUN
admet-2088	347	62	.	.	PUNCT
admet-2088	348	1	the	the	DET
admet-2088	348	2	main	main	ADJ
admet-2088	348	3	issue	issue	NOUN
admet-2088	348	4	remaining	remain	VERB
admet-2088	348	5	with	with	ADP
admet-2088	348	6	conventional	conventional	ADJ
admet-2088	348	7	pdt	pdt	NOUN
admet-2088	348	8	is	be	AUX
admet-2088	348	9	the	the	DET
admet-2088	348	10	limited	limited	ADJ
admet-2088	348	11	penetration	penetration	NOUN
admet-2088	348	12	depth	depth	NOUN
admet-2088	348	13	of	of	ADP
admet-2088	348	14	visible	visible	ADJ
admet-2088	348	15	light	light	NOUN
admet-2088	348	16	into	into	ADP
admet-2088	348	17	the	the	DET
admet-2088	348	18	tumour	tumour	ADJ
admet-2088	348	19	tissue	tissue	NOUN
admet-2088	348	20	essential	essential	ADJ
admet-2088	348	21	for	for	ADP
admet-2088	348	22	its	its	PRON
admet-2088	348	23	activation	activation	NOUN
admet-2088	348	24	.	.	PUNCT
admet-2088	349	1	to	to	PART
admet-2088	349	2	improve	improve	VERB
admet-2088	349	3	upon	upon	SCONJ
admet-2088	349	4	it	it	PRON
admet-2088	349	5	,	,	PUNCT
admet-2088	349	6	mesoporous	mesoporous	ADJ
admet-2088	349	7	-	-	PUNCT
admet-2088	349	8	silica	silica	NOUN
admet-2088	349	9	-	-	PUNCT
admet-2088	349	10	coated	coat	VERB
admet-2088	349	11	upconversion	upconversion	NOUN
admet-2088	349	12	fluorescent	fluorescent	NOUN
admet-2088	349	13	nps	nps	PROPN
admet-2088	349	14	(	(	PUNCT
admet-2088	349	15	ucns	ucns	ADJ
admet-2088	349	16	)	)	PUNCT
admet-2088	349	17	were	be	AUX
admet-2088	349	18	developed	develop	VERB
admet-2088	349	19	by	by	ADP
admet-2088	349	20	idrish	idrish	PROPN
admet-2088	349	21	et	et	PROPN
admet-2088	349	22	al	al	PROPN
admet-2088	349	23	.	.	PUNCT
admet-2088	350	1	[	[	X
admet-2088	350	2	126	126	NUM
admet-2088	350	3	]	]	PUNCT
admet-2088	350	4	,	,	PUNCT
admet-2088	350	5	which	which	PRON
admet-2088	350	6	acted	act	VERB
admet-2088	350	7	as	as	ADP
admet-2088	350	8	carriers	carrier	NOUN
admet-2088	350	9	for	for	ADP
admet-2088	350	10	photosensitizer	photosensitizer	NOUN
admet-2088	350	11	and	and	CCONJ
admet-2088	350	12	as	as	ADP
admet-2088	350	13	a	a	DET
admet-2088	350	14	transducer	transducer	NOUN
admet-2088	350	15	in	in	ADP
admet-2088	350	16	the	the	DET
admet-2088	350	17	conversion	conversion	NOUN
admet-2088	350	18	of	of	ADP
admet-2088	350	19	deeply	deeply	ADV
admet-2088	350	20	penetrating	penetrate	VERB
admet-2088	350	21	nir	nir	ADJ
admet-2088	350	22	light	light	NOUN
admet-2088	350	23	to	to	ADP
admet-2088	350	24	visible	visible	ADJ
admet-2088	350	25	wavelengths	wavelength	NOUN
admet-2088	350	26	.	.	PUNCT
admet-2088	351	1	a	a	DET
admet-2088	351	2	greater	great	ADJ
admet-2088	351	3	pdt	pdt	NOUN
admet-2088	351	4	efficacy	efficacy	NOUN
admet-2088	351	5	with	with	ADP
admet-2088	351	6	the	the	DET
admet-2088	351	7	dual	dual	ADJ
admet-2088	351	8	photosensitizer	photosensitizer	NOUN
admet-2088	351	9	strategy	strategy	NOUN
admet-2088	351	10	in	in	ADP
admet-2088	351	11	comparison	comparison	NOUN
admet-2088	351	12	to	to	ADP
admet-2088	351	13	single	single	ADJ
admet-2088	351	14	photosensitizer	photosensitizer	NOUN
admet-2088	351	15	due	due	ADP
admet-2088	351	16	to	to	ADP
admet-2088	351	17	the	the	DET
admet-2088	351	18	improved	improved	ADJ
admet-2088	351	19	formation	formation	NOUN
admet-2088	351	20	of	of	ADP
admet-2088	351	21	ros	ros	PROPN
admet-2088	351	22	and	and	CCONJ
admet-2088	351	23	reduced	reduced	ADJ
admet-2088	351	24	cell	cell	NOUN
admet-2088	351	25	viability	viability	NOUN
admet-2088	351	26	.	.	PUNCT
admet-2088	352	1	an	an	DET
admet-2088	352	2	in	in	ADP
admet-2088	352	3	vivo	vivo	NOUN
admet-2088	352	4	study	study	NOUN
admet-2088	352	5	on	on	ADP
admet-2088	352	6	tumour	tumour	NOUN
admet-2088	352	7	-	-	PUNCT
admet-2088	352	8	bearing	bear	VERB
admet-2088	352	9	mice	mouse	NOUN
admet-2088	352	10	demonstrated	demonstrate	VERB
admet-2088	352	11	that	that	SCONJ
admet-2088	352	12	there	there	PRON
admet-2088	352	13	was	be	VERB
admet-2088	352	14	tumour	tumour	ADJ
admet-2088	352	15	growth	growth	NOUN
admet-2088	352	16	inhibition	inhibition	NOUN
admet-2088	352	17	in	in	ADP
admet-2088	352	18	pdt	pdt	NOUN
admet-2088	352	19	-	-	PUNCT
admet-2088	352	20	treated	treat	VERB
admet-2088	352	21	mice	mouse	NOUN
admet-2088	352	22	by	by	ADP
admet-2088	352	23	intravenous	intravenous	ADJ
admet-2088	352	24	injection	injection	NOUN
admet-2088	352	25	of	of	ADP
admet-2088	352	26	ucns	ucns	NOUN
admet-2088	352	27	conjugated	conjugate	VERB
admet-2088	352	28	with	with	ADP
admet-2088	352	29	a	a	DET
admet-2088	352	30	tumour	tumour	NOUN
admet-2088	352	31	-	-	PUNCT
admet-2088	352	32	targeting	target	VERB
admet-2088	352	33	agent	agent	NOUN
admet-2088	352	34	or	or	CCONJ
admet-2088	352	35	direct	direct	ADJ
admet-2088	352	36	injection	injection	NOUN
admet-2088	352	37	of	of	ADP
admet-2088	352	38	ucns	ucns	NOUN
admet-2088	352	39	into	into	ADP
admet-2088	352	40	melanoma	melanoma	NOUN
admet-2088	352	41	tumours	tumour	NOUN
admet-2088	352	42	.	.	PUNCT
admet-2088	353	1	in	in	ADP
admet-2088	353	2	an	an	DET
admet-2088	353	3	attempt	attempt	NOUN
admet-2088	353	4	to	to	PART
admet-2088	353	5	enhance	enhance	VERB
admet-2088	353	6	the	the	DET
admet-2088	353	7	delivery	delivery	NOUN
admet-2088	353	8	of	of	ADP
admet-2088	353	9	therapeutics	therapeutic	NOUN
admet-2088	353	10	and	and	CCONJ
admet-2088	353	11	give	give	VERB
admet-2088	353	12	precise	precise	ADJ
admet-2088	353	13	targets	target	NOUN
admet-2088	353	14	to	to	ADP
admet-2088	353	15	disease	disease	NOUN
admet-2088	353	16	sites	site	NOUN
admet-2088	353	17	,	,	PUNCT
admet-2088	353	18	kim	kim	PROPN
admet-2088	353	19	et	et	PROPN
admet-2088	353	20	al	al	PROPN
admet-2088	353	21	.	.	PUNCT
admet-2088	354	1	[	[	X
admet-2088	354	2	127	127	NUM
admet-2088	354	3	]	]	PUNCT
admet-2088	354	4	employed	employ	VERB
admet-2088	354	5	cornell	cornell	PROPN
admet-2088	354	6	dots	dot	NOUN
admet-2088	354	7	,	,	PUNCT
admet-2088	354	8	core	core	NOUN
admet-2088	354	9	-	-	PUNCT
admet-2088	354	10	shell	shell	NOUN
admet-2088	354	11	silica	silica	NOUN
admet-2088	354	12	nps	nps	PROPN
admet-2088	354	13	,	,	PUNCT
admet-2088	354	14	where	where	SCONJ
admet-2088	354	15	sinps	sinps	PROPN
admet-2088	354	16	were	be	AUX
admet-2088	354	17	coated	coat	VERB
admet-2088	354	18	with	with	ADP
admet-2088	354	19	peg	peg	NOUN
admet-2088	354	20	(	(	PUNCT
admet-2088	354	21	pegylated	pegylate	VERB
admet-2088	354	22	sinps	sinps	NOUN
admet-2088	354	23	)	)	PUNCT
admet-2088	354	24	and	and	CCONJ
admet-2088	354	25	functionalized	functionalize	VERB
admet-2088	354	26	with	with	ADP
admet-2088	354	27	conjugating	conjugate	VERB
admet-2088	354	28	melanoma	melanoma	NOUN
admet-2088	354	29	-	-	PUNCT
admet-2088	354	30	targeting	target	VERB
admet-2088	354	31	peptide	peptide	NOUN
admet-2088	354	32	αvβ3	αvβ3	NOUN
admet-2088	354	33	-	-	PUNCT
admet-2088	354	34	integrin	integrin	NOUN
admet-2088	354	35	to	to	ADP
admet-2088	354	36	pegylated	pegylated	ADJ
admet-2088	354	37	sinps	sinps	PROPN
admet-2088	354	38	.	.	PUNCT
admet-2088	355	1	the	the	DET
admet-2088	355	2	ultrasmall	ultrasmall	PROPN
admet-2088	355	3	(	(	PUNCT
admet-2088	355	4	<	<	X
admet-2088	355	5	10	10	NUM
admet-2088	355	6	nm	nm	NOUN
admet-2088	355	7	in	in	ADP
admet-2088	355	8	diameter	diameter	NOUN
admet-2088	355	9	)	)	PUNCT
admet-2088	355	10	pegylated	pegylate	VERB
admet-2088	355	11	sinps	sinps	NOUN
admet-2088	355	12	with	with	ADP
admet-2088	355	13	targeted	target	VERB
admet-2088	355	14	peptides	peptide	NOUN
admet-2088	355	15	induced	induce	VERB
admet-2088	355	16	ferroptosis	ferroptosis	NOUN
admet-2088	355	17	in	in	ADP
admet-2088	355	18	starved	starve	VERB
admet-2088	355	19	cancer	cancer	NOUN
admet-2088	355	20	cells	cell	NOUN
admet-2088	355	21	and	and	CCONJ
admet-2088	355	22	tumour	tumour	PRON
admet-2088	355	23	xenografts	xenograft	NOUN
admet-2088	355	24	in	in	ADP
admet-2088	355	25	mice	mouse	NOUN
admet-2088	355	26	when	when	SCONJ
admet-2088	355	27	injected	inject	VERB
admet-2088	355	28	intravenously	intravenously	ADV
admet-2088	355	29	.	.	PUNCT
admet-2088	356	1	a	a	DET
admet-2088	356	2	nano	nano	NOUN
admet-2088	356	3	-	-	PUNCT
admet-2088	356	4	platform	platform	NOUN
admet-2088	356	5	for	for	ADP
admet-2088	356	6	both	both	CCONJ
admet-2088	356	7	pdt	pdt	PROPN
admet-2088	356	8	and	and	CCONJ
admet-2088	356	9	chemotherapy	chemotherapy	NOUN
admet-2088	356	10	was	be	AUX
admet-2088	356	11	fabricated	fabricate	VERB
admet-2088	356	12	with	with	ADP
admet-2088	356	13	a	a	DET
admet-2088	356	14	gold	gold	NOUN
admet-2088	356	15	nanoshell	nanoshell	NOUN
admet-2088	356	16	on	on	ADP
admet-2088	356	17	rod	rod	NOUN
admet-2088	356	18	-	-	PUNCT
admet-2088	356	19	like	like	ADJ
admet-2088	356	20	mesoporous	mesoporous	ADJ
admet-2088	356	21	silica	silica	NOUN
admet-2088	356	22	nps	nps	PROPN
admet-2088	356	23	with	with	ADP
admet-2088	356	24	different	different	ADJ
admet-2088	356	25	aspect	aspect	NOUN
admet-2088	356	26	ratios	ratio	NOUN
admet-2088	356	27	.	.	PUNCT
admet-2088	357	1	cellular	cellular	ADJ
admet-2088	357	2	uptake	uptake	NOUN
admet-2088	357	3	and	and	CCONJ
admet-2088	357	4	distribution	distribution	NOUN
admet-2088	357	5	of	of	ADP
admet-2088	357	6	nps	nps	PROPN
admet-2088	357	7	in	in	ADP
admet-2088	357	8	tumour	tumour	ADJ
admet-2088	357	9	tissue	tissue	NOUN
admet-2088	357	10	were	be	AUX
admet-2088	357	11	found	find	VERB
admet-2088	357	12	to	to	PART
admet-2088	357	13	be	be	AUX
admet-2088	357	14	significantly	significantly	ADV
admet-2088	357	15	enhanced	enhance	VERB
admet-2088	357	16	with	with	ADP
admet-2088	357	17	aspect	aspect	NOUN
admet-2088	357	18	ratio	ratio	NOUN
admet-2088	357	19	,	,	PUNCT
admet-2088	357	20	and	and	CCONJ
admet-2088	357	21	at	at	ADP
admet-2088	357	22	moderate	moderate	ADJ
admet-2088	357	23	aspect	aspect	NOUN
admet-2088	357	24	ratio	ratio	NOUN
admet-2088	357	25	,	,	PUNCT
admet-2088	357	26	the	the	DET
admet-2088	357	27	gold	gold	NOUN
admet-2088	357	28	nanoshell	nanoshell	NOUN
admet-2088	357	29	was	be	AUX
admet-2088	357	30	able	able	ADJ
admet-2088	357	31	to	to	PART
admet-2088	357	32	penetrate	penetrate	VERB
admet-2088	357	33	melanoma	melanoma	NOUN
admet-2088	357	34	tissues	tissue	NOUN
admet-2088	357	35	,	,	PUNCT
admet-2088	357	36	resulting	result	VERB
admet-2088	357	37	in	in	ADP
admet-2088	357	38	the	the	DET
admet-2088	357	39	potential	potential	ADJ
admet-2088	357	40	ablation	ablation	NOUN
admet-2088	357	41	of	of	ADP
admet-2088	357	42	malignant	malignant	ADJ
admet-2088	357	43	melanoma	melanoma	NOUN
admet-2088	357	44	cells	cell	NOUN
admet-2088	357	45	in	in	ADP
admet-2088	357	46	a	a	DET
admet-2088	357	47	single	single	ADJ
admet-2088	357	48	treatment	treatment	NOUN
admet-2088	357	49	[	[	X
admet-2088	357	50	128	128	NUM
admet-2088	357	51	]	]	PUNCT
admet-2088	357	52	.	.	PUNCT
admet-2088	358	1	to	to	PART
admet-2088	358	2	effectively	effectively	ADV
admet-2088	358	3	trigger	trigger	VERB
admet-2088	358	4	pyroptosis	pyroptosis	NOUN
admet-2088	358	5	at	at	ADP
admet-2088	358	6	the	the	DET
admet-2088	358	7	melanoma	melanoma	NOUN
admet-2088	358	8	site	site	NOUN
admet-2088	358	9	and	and	CCONJ
admet-2088	358	10	to	to	PART
admet-2088	358	11	enhance	enhance	VERB
admet-2088	358	12	the	the	DET
admet-2088	358	13	therapeutic	therapeutic	ADJ
admet-2088	358	14	efficiency	efficiency	NOUN
admet-2088	358	15	,	,	PUNCT
admet-2088	358	16	a	a	DET
admet-2088	358	17	distinct	distinct	ADJ
admet-2088	358	18	2d	2d	NOUN
admet-2088	358	19	core	core	NOUN
admet-2088	358	20	/	/	SYM
admet-2088	358	21	shell	shell	NOUN
admet-2088	358	22	nanosystem	nanosystem	NOUN
admet-2088	358	23	comprised	comprise	VERB
admet-2088	358	24	of	of	ADP
admet-2088	358	25	engineered	engineer	VERB
admet-2088	358	26	mesoporous	mesoporous	ADJ
admet-2088	358	27	silica	silica	NOUN
admet-2088	358	28	layer	layer	NOUN
admet-2088	358	29	and	and	CCONJ
admet-2088	358	30	silicene	silicene	NOUN
admet-2088	358	31	with	with	ADP
admet-2088	358	32	loaded	load	VERB
admet-2088	358	33	cisplatin	cisplatin	NOUN
admet-2088	358	34	was	be	AUX
admet-2088	358	35	designed	design	VERB
admet-2088	358	36	and	and	CCONJ
admet-2088	358	37	fabricated	fabricate	VERB
admet-2088	358	38	to	to	PART
admet-2088	358	39	achieve	achieve	VERB
admet-2088	358	40	synergistic	synergistic	ADJ
admet-2088	358	41	pyroptosis	pyroptosis	NOUN
admet-2088	358	42	and	and	CCONJ
admet-2088	358	43	hyperthermia	hyperthermia	NOUN
admet-2088	358	44	of	of	ADP
admet-2088	358	45	melanoma	melanoma	NOUN
admet-2088	358	46	carcinoma	carcinoma	NOUN
admet-2088	358	47	.	.	PUNCT
admet-2088	359	1	the	the	DET
admet-2088	359	2	surface	surface	NOUN
admet-2088	359	3	-	-	PUNCT
admet-2088	359	4	nanopore	nanopore	ADJ
admet-2088	359	5	engineering	engineering	NOUN
admet-2088	359	6	strategy	strategy	NOUN
admet-2088	359	7	was	be	AUX
admet-2088	359	8	adopted	adopt	VERB
admet-2088	359	9	to	to	PART
admet-2088	359	10	induce	induce	VERB
admet-2088	359	11	surface	surface	NOUN
admet-2088	359	12	functionalization	functionalization	NOUN
admet-2088	359	13	of	of	ADP
admet-2088	359	14	a	a	DET
admet-2088	359	15	2d	2d	NUM
admet-2088	359	16	silicene	silicene	NOUN
admet-2088	359	17	layer	layer	NOUN
admet-2088	359	18	that	that	PRON
admet-2088	359	19	enhanced	enhance	VERB
admet-2088	359	20	hydrophilicity	hydrophilicity	NOUN
admet-2088	359	21	,	,	PUNCT
admet-2088	359	22	provided	provide	VERB
admet-2088	359	23	abundant	abundant	ADJ
admet-2088	359	24	chemical	chemical	ADJ
admet-2088	359	25	groups	group	NOUN
admet-2088	359	26	for	for	ADP
admet-2088	359	27	target	target	NOUN
admet-2088	359	28	modification	modification	NOUN
admet-2088	359	29	and	and	CCONJ
admet-2088	359	30	,	,	PUNCT
admet-2088	359	31	more	more	ADV
admet-2088	359	32	importantly	importantly	ADV
admet-2088	359	33	,	,	PUNCT
admet-2088	359	34	on	on	ADP
admet-2088	359	35	-	-	PUNCT
admet-2088	359	36	demand	demand	NOUN
admet-2088	359	37	drug	drug	NOUN
admet-2088	359	38	delivery	delivery	NOUN
admet-2088	359	39	.	.	PUNCT
admet-2088	360	1	upon	upon	SCONJ
admet-2088	360	2	nir	nir	NOUN
admet-2088	360	3	-	-	PUNCT
admet-2088	360	4	irradiation	irradiation	NOUN
admet-2088	360	5	,	,	PUNCT
admet-2088	360	6	the	the	DET
admet-2088	360	7	2d	2d	NUM
admet-2088	360	8	silicene	silicene	PROPN
admet-2088	360	9	core	core	NOUN
admet-2088	360	10	generated	generate	VERB
admet-2088	360	11	hyperthermia	hyperthermia	NOUN
admet-2088	360	12	,	,	PUNCT
admet-2088	360	13	resulting	result	VERB
admet-2088	360	14	admet	admet	PROPN
admet-2088	360	15	&	&	CCONJ
admet-2088	360	16	dmpk	dmpk	PROPN
admet-2088	360	17	12(1	12(1	PROPN
admet-2088	360	18	)	)	PUNCT
admet-2088	360	19	(	(	PUNCT
admet-2088	360	20	2024	2024	NUM
admet-2088	360	21	)	)	PUNCT
admet-2088	360	22	107	107	NUM
admet-2088	360	23	-	-	SYM
admet-2088	360	24	150	150	NUM
admet-2088	360	25	nanomaterial	nanomaterial	NOUN
admet-2088	360	26	-	-	PUNCT
admet-2088	360	27	based	base	VERB
admet-2088	360	28	drug	drug	NOUN
admet-2088	360	29	delivery	delivery	NOUN
admet-2088	360	30	systems	system	NOUN
admet-2088	360	31	for	for	ADP
admet-2088	360	32	melanoma	melanoma	NOUN
admet-2088	360	33	therapy	therapy	NOUN
admet-2088	360	34	doi	doi	NOUN
admet-2088	360	35	:	:	PUNCT
admet-2088	360	36	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	360	37	121	121	NUM
admet-2088	360	38	in	in	ADP
admet-2088	360	39	cisplatin	cisplatin	NOUN
admet-2088	360	40	release	release	NOUN
admet-2088	360	41	for	for	ADP
admet-2088	360	42	activating	activate	VERB
admet-2088	360	43	caspase-3	caspase-3	NUM
admet-2088	360	44	,	,	PUNCT
admet-2088	360	45	cleaving	cleave	VERB
admet-2088	360	46	gasdermin	gasdermin	NOUN
admet-2088	360	47	e	e	NOUN
admet-2088	360	48	(	(	PUNCT
admet-2088	360	49	a	a	DET
admet-2088	360	50	protein	protein	NOUN
admet-2088	360	51	-	-	PUNCT
admet-2088	360	52	coding	code	VERB
admet-2088	360	53	gene	gene	NOUN
admet-2088	360	54	,	,	PUNCT
admet-2088	360	55	csdme	csdme	NOUN
admet-2088	360	56	)	)	PUNCT
admet-2088	360	57	into	into	ADP
admet-2088	360	58	the	the	DET
admet-2088	360	59	gadme	gadme	NOUN
admet-2088	360	60	-	-	PUNCT
admet-2088	360	61	n	n	CCONJ
admet-2088	360	62	terminal	terminal	ADJ
admet-2088	360	63	and	and	CCONJ
admet-2088	360	64	further	far	ADV
admet-2088	360	65	inducing	induce	VERB
admet-2088	360	66	pyroptosis	pyroptosis	NOUN
admet-2088	360	67	.	.	PUNCT
admet-2088	361	1	both	both	PRON
admet-2088	361	2	in	in	ADP
admet-2088	361	3	vitro	vitro	X
admet-2088	361	4	and	and	CCONJ
admet-2088	361	5	in	in	ADP
admet-2088	361	6	vivo	vivo	ADJ
admet-2088	361	7	studies	study	NOUN
admet-2088	361	8	showed	show	VERB
admet-2088	361	9	that	that	SCONJ
admet-2088	361	10	the	the	DET
admet-2088	361	11	nanosystem	nanosystem	NOUN
admet-2088	361	12	has	have	AUX
admet-2088	361	13	active	active	ADJ
admet-2088	361	14	targeting	targeting	NOUN
admet-2088	361	15	potential	potential	NOUN
admet-2088	361	16	into	into	ADP
admet-2088	361	17	tumours	tumour	NOUN
admet-2088	361	18	and	and	CCONJ
admet-2088	361	19	synergistic	synergistic	ADJ
admet-2088	361	20	pyroptosis	pyroptosis	NOUN
admet-2088	361	21	(	(	PUNCT
admet-2088	361	22	release	release	NOUN
admet-2088	361	23	of	of	ADP
admet-2088	361	24	cisplatin	cisplatin	NOUN
admet-2088	361	25	and	and	CCONJ
admet-2088	361	26	hyperthermia	hyperthermia	NOUN
admet-2088	361	27	)	)	PUNCT
admet-2088	361	28	,	,	PUNCT
admet-2088	361	29	thus	thus	ADV
admet-2088	361	30	significantly	significantly	ADV
admet-2088	361	31	eradicating	eradicate	VERB
admet-2088	361	32	melanoma	melanoma	NOUN
admet-2088	361	33	without	without	ADP
admet-2088	361	34	any	any	DET
admet-2088	361	35	adverse	adverse	ADJ
admet-2088	361	36	effect	effect	NOUN
admet-2088	361	37	[	[	X
admet-2088	361	38	129	129	NUM
admet-2088	361	39	]	]	PUNCT
admet-2088	361	40	.	.	PUNCT
admet-2088	362	1	sapino	sapino	PROPN
admet-2088	362	2	et	et	PROPN
admet-2088	362	3	al	al	PROPN
admet-2088	362	4	.	.	PUNCT
admet-2088	363	1	[	[	X
admet-2088	363	2	130	130	NUM
admet-2088	363	3	]	]	PUNCT
admet-2088	363	4	functionnalized	functionnalize	VERB
admet-2088	363	5	the	the	DET
admet-2088	363	6	mobil	mobil	NOUN
admet-2088	363	7	composition	composition	NOUN
admet-2088	363	8	of	of	ADP
admet-2088	363	9	matter	matter	NOUN
admet-2088	363	10	no	no	DET
admet-2088	363	11	41	41	NUM
admet-2088	363	12	(	(	PUNCT
admet-2088	363	13	mcm-41	mcm-41	PROPN
admet-2088	363	14	)	)	PUNCT
admet-2088	363	15	,	,	PUNCT
admet-2088	363	16	which	which	PRON
admet-2088	363	17	is	be	AUX
admet-2088	363	18	a	a	DET
admet-2088	363	19	mesoporous	mesoporous	ADJ
admet-2088	363	20	material	material	NOUN
admet-2088	363	21	with	with	ADP
admet-2088	363	22	a	a	DET
admet-2088	363	23	hierarchical	hierarchical	ADJ
admet-2088	363	24	structure	structure	NOUN
admet-2088	363	25	composed	compose	VERB
admet-2088	363	26	of	of	ADP
admet-2088	363	27	silicate	silicate	NOUN
admet-2088	363	28	and	and	CCONJ
admet-2088	363	29	alumosilicate	alumosilicate	ADJ
admet-2088	363	30	,	,	PUNCT
admet-2088	363	31	with	with	ADP
admet-2088	363	32	the	the	DET
admet-2088	363	33	aminopropyl	aminopropyl	PROPN
admet-2088	363	34	group	group	NOUN
admet-2088	363	35	and	and	CCONJ
admet-2088	363	36	then	then	ADV
admet-2088	363	37	loaded	load	VERB
admet-2088	363	38	it	it	PRON
admet-2088	363	39	with	with	ADP
admet-2088	363	40	flavonoid	flavonoid	PROPN
admet-2088	363	41	quercetin	quercetin	NOUN
admet-2088	363	42	.	.	PUNCT
admet-2088	364	1	the	the	DET
admet-2088	364	2	np	np	PROPN
admet-2088	364	3	system	system	NOUN
admet-2088	364	4	was	be	AUX
admet-2088	364	5	found	find	VERB
admet-2088	364	6	to	to	PART
admet-2088	364	7	improve	improve	VERB
admet-2088	364	8	the	the	DET
admet-2088	364	9	stability	stability	NOUN
admet-2088	364	10	of	of	ADP
admet-2088	364	11	quercetin	quercetin	NOUN
admet-2088	364	12	and	and	CCONJ
admet-2088	364	13	enhance	enhance	VERB
admet-2088	364	14	quercetin	quercetin	NOUN
admet-2088	364	15	penetration	penetration	NOUN
admet-2088	364	16	across	across	ADP
admet-2088	364	17	the	the	DET
admet-2088	364	18	skin	skin	NOUN
admet-2088	364	19	.	.	PUNCT
admet-2088	365	1	further	far	ADV
admet-2088	365	2	,	,	PUNCT
admet-2088	365	3	the	the	DET
admet-2088	365	4	nanosystem	nanosystem	NOUN
admet-2088	365	5	showed	show	VERB
admet-2088	365	6	inhibition	inhibition	NOUN
admet-2088	365	7	of	of	ADP
admet-2088	365	8	cancer	cancer	NOUN
admet-2088	365	9	cell	cell	NOUN
admet-2088	365	10	proliferation	proliferation	NOUN
admet-2088	365	11	in	in	ADP
admet-2088	365	12	melanoma	melanoma	NOUN
admet-2088	365	13	cell	cell	NOUN
admet-2088	365	14	line	line	NOUN
admet-2088	365	15	jr8	jr8	PROPN
admet-2088	365	16	.	.	PUNCT
admet-2088	366	1	titanium	titanium	NOUN
admet-2088	366	2	dioxide	dioxide	NOUN
admet-2088	366	3	nanoparticles	nanoparticle	NOUN
admet-2088	366	4	tio2	tio2	NOUN
admet-2088	366	5	has	have	AUX
admet-2088	366	6	been	be	AUX
admet-2088	366	7	widely	widely	ADV
admet-2088	366	8	used	use	VERB
admet-2088	366	9	in	in	ADP
admet-2088	366	10	dermal	dermal	ADJ
admet-2088	366	11	creams	cream	NOUN
admet-2088	366	12	,	,	PUNCT
admet-2088	366	13	lotions	lotion	NOUN
admet-2088	366	14	,	,	PUNCT
admet-2088	366	15	sun	sun	NOUN
admet-2088	366	16	protection	protection	NOUN
admet-2088	366	17	creams	cream	NOUN
admet-2088	366	18	and	and	CCONJ
admet-2088	366	19	other	other	ADJ
admet-2088	366	20	cosmetics	cosmetic	NOUN
admet-2088	366	21	for	for	ADP
admet-2088	366	22	the	the	DET
admet-2088	366	23	protection	protection	NOUN
admet-2088	366	24	of	of	ADP
admet-2088	366	25	skin	skin	NOUN
admet-2088	366	26	against	against	ADP
admet-2088	366	27	uv	uv	NOUN
admet-2088	366	28	light	light	NOUN
admet-2088	366	29	that	that	PRON
admet-2088	366	30	has	have	VERB
admet-2088	366	31	the	the	DET
admet-2088	366	32	potential	potential	NOUN
admet-2088	366	33	to	to	PART
admet-2088	366	34	cause	cause	VERB
admet-2088	366	35	melanoma	melanoma	NOUN
admet-2088	366	36	.	.	PUNCT
admet-2088	367	1	this	this	PRON
admet-2088	367	2	is	be	AUX
admet-2088	367	3	feasible	feasible	ADJ
admet-2088	367	4	due	due	ADP
admet-2088	367	5	to	to	ADP
admet-2088	367	6	its	its	PRON
admet-2088	367	7	biocompatibility	biocompatibility	NOUN
admet-2088	367	8	,	,	PUNCT
admet-2088	367	9	penetration	penetration	NOUN
admet-2088	367	10	ability	ability	NOUN
admet-2088	367	11	when	when	SCONJ
admet-2088	367	12	the	the	DET
admet-2088	367	13	size	size	NOUN
admet-2088	367	14	is	be	AUX
admet-2088	367	15	5	5	NUM
admet-2088	367	16	-	-	SYM
admet-2088	367	17	20	20	NUM
admet-2088	367	18	nm	nm	NOUN
admet-2088	367	19	,	,	PUNCT
admet-2088	367	20	reactivity	reactivity	NOUN
admet-2088	367	21	and	and	CCONJ
admet-2088	367	22	chemical	chemical	NOUN
admet-2088	367	23	stability	stability	NOUN
admet-2088	367	24	.	.	PUNCT
admet-2088	368	1	tio2	tio2	PROPN
admet-2088	368	2	nps	nps	PROPN
admet-2088	368	3	can	can	AUX
admet-2088	368	4	be	be	AUX
admet-2088	368	5	used	use	VERB
admet-2088	368	6	as	as	ADP
admet-2088	368	7	anticancer	anticancer	NOUN
admet-2088	368	8	agents	agent	NOUN
admet-2088	368	9	because	because	SCONJ
admet-2088	368	10	of	of	ADP
admet-2088	368	11	their	their	PRON
admet-2088	368	12	high	high	ADJ
admet-2088	368	13	accumulation	accumulation	NOUN
admet-2088	368	14	in	in	ADP
admet-2088	368	15	cells	cell	NOUN
admet-2088	368	16	,	,	PUNCT
admet-2088	368	17	resulting	result	VERB
admet-2088	368	18	in	in	ADP
admet-2088	368	19	modification	modification	NOUN
admet-2088	368	20	in	in	ADP
admet-2088	368	21	gene	gene	NOUN
admet-2088	368	22	expression	expression	NOUN
admet-2088	368	23	,	,	PUNCT
admet-2088	368	24	inflammatory	inflammatory	ADJ
admet-2088	368	25	responses	response	NOUN
admet-2088	368	26	,	,	PUNCT
admet-2088	368	27	oxidative	oxidative	ADJ
admet-2088	368	28	dna	dna	NOUN
admet-2088	368	29	damage	damage	NOUN
admet-2088	368	30	,	,	PUNCT
admet-2088	368	31	and	and	CCONJ
admet-2088	368	32	lipid	lipid	NOUN
admet-2088	368	33	peroxidation	peroxidation	NOUN
admet-2088	368	34	,	,	PUNCT
admet-2088	368	35	leading	lead	VERB
admet-2088	368	36	to	to	ADP
admet-2088	368	37	necrosis	necrosis	NOUN
admet-2088	368	38	or	or	CCONJ
admet-2088	368	39	programmed	program	VERB
admet-2088	368	40	cell	cell	NOUN
admet-2088	368	41	death	death	NOUN
admet-2088	369	1	[	[	X
admet-2088	369	2	69,131	69,131	NUM
admet-2088	369	3	]	]	PUNCT
admet-2088	369	4	.	.	PUNCT
admet-2088	370	1	in	in	ADP
admet-2088	370	2	addition	addition	NOUN
admet-2088	370	3	,	,	PUNCT
admet-2088	370	4	tio2	tio2	PROPN
admet-2088	370	5	nps	nps	PROPN
admet-2088	370	6	are	be	AUX
admet-2088	370	7	most	most	ADV
admet-2088	370	8	often	often	ADV
admet-2088	370	9	used	use	VERB
admet-2088	370	10	in	in	ADP
admet-2088	370	11	phototherapy	phototherapy	NOUN
admet-2088	370	12	as	as	SCONJ
admet-2088	370	13	they	they	PRON
admet-2088	370	14	exhibit	exhibit	VERB
admet-2088	370	15	excellent	excellent	ADJ
admet-2088	370	16	optical	optical	ADJ
admet-2088	370	17	,	,	PUNCT
admet-2088	370	18	electrical	electrical	ADJ
admet-2088	370	19	,	,	PUNCT
admet-2088	370	20	magnetic	magnetic	ADJ
admet-2088	370	21	,	,	PUNCT
admet-2088	370	22	photocatalytic	photocatalytic	ADJ
admet-2088	370	23	,	,	PUNCT
admet-2088	370	24	structural	structural	ADJ
admet-2088	370	25	stability	stability	NOUN
admet-2088	370	26	and	and	CCONJ
admet-2088	370	27	biocompatibility	biocompatibility	NOUN
admet-2088	371	1	[	[	X
admet-2088	371	2	132,133	132,133	NUM
admet-2088	371	3	]	]	PUNCT
admet-2088	371	4	.	.	PUNCT
admet-2088	372	1	being	be	AUX
admet-2088	372	2	a	a	DET
admet-2088	372	3	photoactive	photoactive	ADJ
admet-2088	372	4	agent	agent	NOUN
admet-2088	372	5	,	,	PUNCT
admet-2088	372	6	tio2	tio2	PROPN
admet-2088	372	7	nps	nps	PROPN
admet-2088	372	8	act	act	PROPN
admet-2088	372	9	as	as	ADP
admet-2088	372	10	anticancer	anticancer	NOUN
admet-2088	372	11	agents	agent	NOUN
admet-2088	372	12	through	through	ADP
admet-2088	372	13	activation	activation	NOUN
admet-2088	372	14	through	through	ADP
admet-2088	372	15	light	light	ADJ
admet-2088	372	16	and	and	CCONJ
admet-2088	372	17	ultrasound	ultrasound	NOUN
admet-2088	372	18	waves	wave	NOUN
admet-2088	372	19	,	,	PUNCT
admet-2088	372	20	promoting	promote	VERB
admet-2088	372	21	the	the	DET
admet-2088	372	22	generation	generation	NOUN
admet-2088	372	23	of	of	ADP
admet-2088	372	24	heat	heat	NOUN
admet-2088	372	25	or	or	CCONJ
admet-2088	372	26	ros	ros	PROPN
admet-2088	372	27	[	[	X
admet-2088	372	28	134	134	NUM
admet-2088	372	29	]	]	PUNCT
admet-2088	372	30	.	.	PUNCT
admet-2088	373	1	curcumin	curcumin	NOUN
admet-2088	373	2	is	be	AUX
admet-2088	373	3	a	a	DET
admet-2088	373	4	well	well	ADV
admet-2088	373	5	-	-	PUNCT
admet-2088	373	6	established	establish	VERB
admet-2088	373	7	therapeutic	therapeutic	ADJ
admet-2088	373	8	agent	agent	NOUN
admet-2088	373	9	,	,	PUNCT
admet-2088	373	10	but	but	CCONJ
admet-2088	373	11	its	its	PRON
admet-2088	373	12	clinical	clinical	ADJ
admet-2088	373	13	application	application	NOUN
admet-2088	373	14	is	be	AUX
admet-2088	373	15	limited	limit	VERB
admet-2088	373	16	because	because	SCONJ
admet-2088	373	17	of	of	ADP
admet-2088	373	18	its	its	PRON
admet-2088	373	19	hydrophobic	hydrophobic	NOUN
admet-2088	373	20	nature	nature	NOUN
admet-2088	373	21	,	,	PUNCT
admet-2088	373	22	resulting	result	VERB
admet-2088	373	23	in	in	ADP
admet-2088	373	24	low	low	ADJ
admet-2088	373	25	bioavailability	bioavailability	NOUN
admet-2088	373	26	.	.	PUNCT
admet-2088	374	1	thus	thus	ADV
admet-2088	374	2	,	,	PUNCT
admet-2088	374	3	tio2	tio2	PROPN
admet-2088	374	4	nps	nps	PROPN
admet-2088	374	5	were	be	AUX
admet-2088	374	6	initially	initially	ADV
admet-2088	374	7	coated	coat	VERB
admet-2088	374	8	with	with	ADP
admet-2088	374	9	chitosan	chitosan	NOUN
admet-2088	374	10	to	to	PART
admet-2088	374	11	enhance	enhance	VERB
admet-2088	374	12	their	their	PRON
admet-2088	374	13	stability	stability	NOUN
admet-2088	374	14	and	and	CCONJ
admet-2088	374	15	biocompatibility	biocompatibility	NOUN
admet-2088	374	16	and	and	CCONJ
admet-2088	374	17	then	then	ADV
admet-2088	374	18	curcumin	curcumin	NOUN
admet-2088	374	19	molecules	molecule	NOUN
admet-2088	374	20	were	be	AUX
admet-2088	374	21	conjugated	conjugate	VERB
admet-2088	374	22	onto	onto	ADP
admet-2088	374	23	them	they	PRON
admet-2088	374	24	to	to	PART
admet-2088	374	25	form	form	VERB
admet-2088	374	26	nanocomposite	nanocomposite	PROPN
admet-2088	374	27	(	(	PUNCT
admet-2088	374	28	ticurnc	ticurnc	ADJ
admet-2088	374	29	)	)	PUNCT
admet-2088	374	30	.	.	PUNCT
admet-2088	375	1	these	these	DET
admet-2088	375	2	nanocomposites	nanocomposite	NOUN
admet-2088	375	3	showed	show	VERB
admet-2088	375	4	exceptional	exceptional	ADJ
admet-2088	375	5	selectivity	selectivity	NOUN
admet-2088	375	6	towards	towards	ADP
admet-2088	375	7	the	the	DET
admet-2088	375	8	melanoma	melanoma	NOUN
admet-2088	375	9	cell	cell	NOUN
admet-2088	375	10	line	line	NOUN
admet-2088	375	11	(	(	PUNCT
admet-2088	375	12	b16f10	b16f10	NOUN
admet-2088	375	13	)	)	PUNCT
admet-2088	375	14	while	while	SCONJ
admet-2088	375	15	minimizing	minimize	VERB
admet-2088	375	16	toxicity	toxicity	NOUN
admet-2088	375	17	to	to	ADP
admet-2088	375	18	normal	normal	ADJ
admet-2088	375	19	cells	cell	NOUN
admet-2088	375	20	(	(	PUNCT
admet-2088	375	21	cho	cho	ADJ
admet-2088	375	22	–	–	PUNCT
admet-2088	375	23	k1	k1	NOUN
admet-2088	375	24	cells	cell	NOUN
admet-2088	375	25	)	)	PUNCT
admet-2088	375	26	.	.	PUNCT
admet-2088	376	1	the	the	DET
admet-2088	376	2	potent	potent	ADJ
admet-2088	376	3	anticancer	anticancer	NOUN
admet-2088	376	4	activity	activity	NOUN
admet-2088	376	5	against	against	ADP
admet-2088	376	6	melanoma	melanoma	NOUN
admet-2088	376	7	cells	cell	NOUN
admet-2088	376	8	was	be	AUX
admet-2088	376	9	due	due	ADJ
admet-2088	376	10	to	to	ADP
admet-2088	376	11	the	the	DET
admet-2088	376	12	increased	increase	VERB
admet-2088	376	13	intracellular	intracellular	ADJ
admet-2088	376	14	content	content	NOUN
admet-2088	376	15	of	of	ADP
admet-2088	376	16	curcumin	curcumin	NOUN
admet-2088	376	17	,	,	PUNCT
admet-2088	376	18	followed	follow	VERB
admet-2088	376	19	by	by	ADP
admet-2088	376	20	the	the	DET
admet-2088	376	21	induction	induction	NOUN
admet-2088	376	22	of	of	ADP
admet-2088	376	23	mitochondria	mitochondria	NOUN
admet-2088	376	24	to	to	PART
admet-2088	376	25	produce	produce	VERB
admet-2088	376	26	more	more	ADJ
admet-2088	376	27	ros	ro	NOUN
admet-2088	376	28	,	,	PUNCT
admet-2088	376	29	which	which	PRON
admet-2088	376	30	interacts	interact	VERB
admet-2088	376	31	with	with	ADP
admet-2088	376	32	the	the	DET
admet-2088	376	33	dna	dna	NOUN
admet-2088	376	34	and	and	CCONJ
admet-2088	376	35	causes	cause	VERB
admet-2088	376	36	its	its	PRON
admet-2088	376	37	damage	damage	NOUN
admet-2088	376	38	and	and	CCONJ
admet-2088	376	39	apoptosis	apoptosis	NOUN
admet-2088	376	40	.	.	PUNCT
admet-2088	377	1	in	in	ADP
admet-2088	377	2	addition	addition	NOUN
admet-2088	377	3	,	,	PUNCT
admet-2088	377	4	it	it	PRON
admet-2088	377	5	is	be	AUX
admet-2088	377	6	responsible	responsible	ADJ
admet-2088	377	7	for	for	ADP
admet-2088	377	8	stopping	stop	VERB
admet-2088	377	9	the	the	DET
admet-2088	377	10	cells	cell	NOUN
admet-2088	377	11	at	at	ADP
admet-2088	377	12	the	the	DET
admet-2088	377	13	g2	g2	PROPN
admet-2088	377	14	/	/	SYM
admet-2088	377	15	m	m	PROPN
admet-2088	377	16	phase	phase	NOUN
admet-2088	377	17	[	[	X
admet-2088	377	18	135	135	NUM
admet-2088	377	19	]	]	PUNCT
admet-2088	377	20	.	.	PUNCT
admet-2088	378	1	iron	iron	NOUN
admet-2088	378	2	oxide	oxide	NOUN
admet-2088	378	3	nanoparticles	nanoparticle	NOUN
admet-2088	378	4	iron	iron	NOUN
admet-2088	378	5	oxide	oxide	NOUN
admet-2088	378	6	nps	nps	PROPN
admet-2088	378	7	or	or	CCONJ
admet-2088	378	8	magnetic	magnetic	PROPN
admet-2088	378	9	nps	nps	PROPN
admet-2088	378	10	referred	refer	VERB
admet-2088	378	11	to	to	ADP
admet-2088	378	12	as	as	SCONJ
admet-2088	378	13	fe3o4	fe3o4	PROPN
admet-2088	378	14	and	and	CCONJ
admet-2088	378	15	fe2o3	fe2o3	PROPN
admet-2088	378	16	were	be	AUX
admet-2088	378	17	first	first	ADV
admet-2088	378	18	explored	explore	VERB
admet-2088	378	19	in	in	ADP
admet-2088	378	20	drug	drug	NOUN
admet-2088	378	21	delivery	delivery	NOUN
admet-2088	378	22	by	by	ADP
admet-2088	378	23	widder	widder	X
admet-2088	378	24	et	et	PROPN
admet-2088	378	25	al	al	PROPN
admet-2088	378	26	.	.	PUNCT
admet-2088	379	1	[	[	X
admet-2088	379	2	136	136	NUM
admet-2088	379	3	]	]	PUNCT
admet-2088	379	4	in	in	ADP
admet-2088	379	5	1979	1979	NUM
admet-2088	379	6	.	.	PUNCT
admet-2088	380	1	these	these	DET
admet-2088	380	2	nps	nps	PROPN
admet-2088	380	3	are	be	AUX
admet-2088	380	4	approved	approve	VERB
admet-2088	380	5	by	by	ADP
admet-2088	380	6	the	the	DET
admet-2088	380	7	fda	fda	PROPN
admet-2088	380	8	for	for	ADP
admet-2088	380	9	therapeutic	therapeutic	ADJ
admet-2088	380	10	and	and	CCONJ
admet-2088	380	11	imaging	imaging	NOUN
admet-2088	380	12	use	use	NOUN
admet-2088	380	13	due	due	ADP
admet-2088	380	14	to	to	ADP
admet-2088	380	15	their	their	PRON
admet-2088	380	16	controlled	control	VERB
admet-2088	380	17	size	size	NOUN
admet-2088	380	18	,	,	PUNCT
admet-2088	380	19	possibilities	possibility	NOUN
admet-2088	380	20	of	of	ADP
admet-2088	380	21	surface	surface	NOUN
admet-2088	380	22	modification	modification	NOUN
admet-2088	380	23	,	,	PUNCT
admet-2088	380	24	extremely	extremely	ADV
admet-2088	380	25	low	low	ADJ
admet-2088	380	26	toxicity	toxicity	NOUN
admet-2088	380	27	,	,	PUNCT
admet-2088	380	28	magnetic	magnetic	ADJ
admet-2088	380	29	responsiveness	responsiveness	NOUN
admet-2088	380	30	and	and	CCONJ
admet-2088	380	31	contrast	contrast	VERB
admet-2088	380	32	agent	agent	NOUN
admet-2088	380	33	for	for	ADP
admet-2088	380	34	magnetic	magnetic	ADJ
admet-2088	380	35	resonance	resonance	NOUN
admet-2088	380	36	imaging	imaging	NOUN
admet-2088	380	37	[	[	X
admet-2088	380	38	137	137	NUM
admet-2088	380	39	]	]	PUNCT
admet-2088	380	40	.	.	PUNCT
admet-2088	381	1	when	when	SCONJ
admet-2088	381	2	induced	induce	VERB
admet-2088	381	3	by	by	ADP
admet-2088	381	4	external	external	ADJ
admet-2088	381	5	electromagnetic	electromagnetic	ADJ
admet-2088	381	6	fields	field	NOUN
admet-2088	381	7	,	,	PUNCT
admet-2088	381	8	iron	iron	NOUN
admet-2088	381	9	oxide	oxide	NOUN
admet-2088	381	10	nps	nps	PROPN
admet-2088	381	11	play	play	VERB
admet-2088	381	12	a	a	DET
admet-2088	381	13	crucial	crucial	ADJ
admet-2088	381	14	role	role	NOUN
admet-2088	381	15	in	in	ADP
admet-2088	381	16	their	their	PRON
admet-2088	381	17	transfection	transfection	NOUN
admet-2088	381	18	and	and	CCONJ
admet-2088	381	19	delivery	delivery	NOUN
admet-2088	381	20	along	along	ADP
admet-2088	381	21	with	with	ADP
admet-2088	381	22	the	the	DET
admet-2088	381	23	conjugated	conjugated	ADJ
admet-2088	381	24	or	or	CCONJ
admet-2088	381	25	coated	coat	VERB
admet-2088	381	26	therapeutic	therapeutic	ADJ
admet-2088	381	27	agents	agent	NOUN
admet-2088	381	28	[	[	X
admet-2088	381	29	138	138	NUM
admet-2088	381	30	]	]	PUNCT
admet-2088	381	31	.	.	PUNCT
admet-2088	382	1	magnetic	magnetic	ADJ
admet-2088	382	2	medication	medication	NOUN
admet-2088	382	3	delivery	delivery	NOUN
admet-2088	382	4	minimally	minimally	ADV
admet-2088	382	5	comprises	comprise	VERB
admet-2088	382	6	an	an	DET
admet-2088	382	7	inorganic	inorganic	ADJ
admet-2088	382	8	material	material	NOUN
admet-2088	382	9	core	core	NOUN
admet-2088	382	10	(	(	PUNCT
admet-2088	382	11	iron	iron	NOUN
admet-2088	382	12	oxide	oxide	NOUN
admet-2088	382	13	nps	nps	PROPN
admet-2088	382	14	)	)	PUNCT
admet-2088	382	15	and	and	CCONJ
admet-2088	382	16	a	a	DET
admet-2088	382	17	surface	surface	NOUN
admet-2088	382	18	coating	coating	NOUN
admet-2088	382	19	in	in	ADP
admet-2088	382	20	order	order	NOUN
admet-2088	382	21	to	to	PART
admet-2088	382	22	enhance	enhance	VERB
admet-2088	382	23	biocompatibility	biocompatibility	NOUN
admet-2088	382	24	,	,	PUNCT
admet-2088	382	25	half	half	ADJ
admet-2088	382	26	-	-	PUNCT
admet-2088	382	27	life	life	NOUN
admet-2088	382	28	and	and	CCONJ
admet-2088	382	29	stability	stability	NOUN
admet-2088	382	30	[	[	X
admet-2088	382	31	139	139	NUM
admet-2088	382	32	]	]	PUNCT
admet-2088	382	33	.	.	PUNCT
admet-2088	383	1	for	for	ADP
admet-2088	383	2	instance	instance	NOUN
admet-2088	383	3	,	,	PUNCT
admet-2088	383	4	polymer	polymer	NOUN
admet-2088	383	5	(	(	PUNCT
admet-2088	383	6	e.g.	e.g.	ADV
admet-2088	383	7	,	,	PUNCT
admet-2088	383	8	dextran	dextran	NOUN
admet-2088	383	9	,	,	PUNCT
admet-2088	383	10	chitosan	chitosan	NOUN
admet-2088	383	11	)	)	PUNCT
admet-2088	383	12	or	or	CCONJ
admet-2088	383	13	organic	organic	ADJ
admet-2088	383	14	surfactant	surfactant	NOUN
admet-2088	383	15	(	(	PUNCT
admet-2088	383	16	e.g.	e.g.	ADV
admet-2088	383	17	,	,	PUNCT
admet-2088	383	18	sodium	sodium	NOUN
admet-2088	383	19	oleate	oleate	NOUN
admet-2088	383	20	)	)	PUNCT
admet-2088	383	21	coating	coating	NOUN
admet-2088	383	22	of	of	ADP
admet-2088	383	23	iron	iron	NOUN
admet-2088	383	24	oxide	oxide	NOUN
admet-2088	383	25	acts	act	NOUN
admet-2088	383	26	as	as	ADP
admet-2088	383	27	a	a	DET
admet-2088	383	28	barrier	barrier	NOUN
admet-2088	383	29	and	and	CCONJ
admet-2088	383	30	thus	thus	ADV
admet-2088	383	31	prevents	prevent	VERB
admet-2088	383	32	reticuloendothelial	reticuloendothelial	ADJ
admet-2088	383	33	system	system	NOUN
admet-2088	383	34	absorption	absorption	NOUN
admet-2088	383	35	and	and	CCONJ
admet-2088	383	36	np	np	ADP
admet-2088	383	37	agglomeration	agglomeration	NOUN
admet-2088	383	38	[	[	X
admet-2088	383	39	140	140	NUM
admet-2088	383	40	]	]	PUNCT
admet-2088	383	41	.	.	PUNCT
admet-2088	384	1	reduction	reduction	NOUN
admet-2088	384	2	of	of	ADP
admet-2088	384	3	particle	particle	NOUN
admet-2088	384	4	size	size	NOUN
admet-2088	384	5	of	of	ADP
admet-2088	384	6	iron	iron	NOUN
admet-2088	384	7	oxide	oxide	NOUN
admet-2088	384	8	below	below	ADP
admet-2088	384	9	100	100	NUM
admet-2088	384	10	nm	nm	NOUN
admet-2088	384	11	may	may	AUX
admet-2088	384	12	lead	lead	VERB
admet-2088	384	13	to	to	ADP
admet-2088	384	14	thermal	thermal	ADJ
admet-2088	384	15	energy	energy	NOUN
admet-2088	384	16	equal	equal	ADJ
admet-2088	384	17	to	to	ADP
admet-2088	384	18	its	its	PRON
admet-2088	384	19	anisotropy	anisotropy	NOUN
admet-2088	384	20	energy	energy	NOUN
admet-2088	384	21	and	and	CCONJ
admet-2088	384	22	exhibit	exhibit	VERB
admet-2088	384	23	superparamagnetic	superparamagnetic	ADJ
admet-2088	384	24	nature	nature	NOUN
admet-2088	384	25	.	.	PUNCT
admet-2088	385	1	this	this	DET
admet-2088	385	2	property	property	NOUN
admet-2088	385	3	of	of	ADP
admet-2088	385	4	iron	iron	NOUN
admet-2088	385	5	oxide	oxide	NOUN
admet-2088	385	6	nps	nps	PROPN
admet-2088	385	7	enables	enable	VERB
admet-2088	385	8	them	they	PRON
admet-2088	385	9	to	to	PART
admet-2088	385	10	heat	heat	VERB
admet-2088	385	11	up	up	ADP
admet-2088	385	12	under	under	ADP
admet-2088	385	13	the	the	DET
admet-2088	385	14	influence	influence	NOUN
admet-2088	385	15	of	of	ADP
admet-2088	385	16	magnetic	magnetic	ADJ
admet-2088	385	17	fields	field	NOUN
admet-2088	385	18	to	to	PART
admet-2088	385	19	induce	induce	VERB
admet-2088	385	20	hyperthermia	hyperthermia	NOUN
admet-2088	385	21	and	and	CCONJ
admet-2088	385	22	subsequent	subsequent	ADJ
admet-2088	385	23	thermal	thermal	ADJ
admet-2088	385	24	ablation	ablation	NOUN
admet-2088	385	25	of	of	ADP
admet-2088	385	26	tumours	tumours	PROPN
admet-2088	385	27	[	[	X
admet-2088	385	28	72	72	NUM
admet-2088	385	29	]	]	PUNCT
admet-2088	385	30	.	.	PUNCT
admet-2088	386	1	polyphenols	polyphenol	NOUN
admet-2088	386	2	are	be	AUX
admet-2088	386	3	plant	plant	NOUN
admet-2088	386	4	-	-	PUNCT
admet-2088	386	5	derived	derive	VERB
admet-2088	386	6	constituents	constituent	NOUN
admet-2088	386	7	that	that	PRON
admet-2088	386	8	can	can	AUX
admet-2088	386	9	self	self	NOUN
admet-2088	386	10	-	-	PUNCT
admet-2088	386	11	assemble	assemble	VERB
admet-2088	386	12	with	with	ADP
admet-2088	386	13	metal	metal	NOUN
admet-2088	386	14	ions	ion	NOUN
admet-2088	386	15	to	to	PART
admet-2088	386	16	form	form	VERB
admet-2088	386	17	a	a	DET
admet-2088	386	18	metalpolyphenol	metalpolyphenol	ADJ
admet-2088	386	19	network	network	NOUN
admet-2088	386	20	(	(	PUNCT
admet-2088	386	21	mpn	mpn	PROPN
admet-2088	386	22	)	)	PUNCT
admet-2088	386	23	through	through	ADP
admet-2088	386	24	a	a	DET
admet-2088	386	25	chelate	chelate	NOUN
admet-2088	386	26	reaction	reaction	NOUN
admet-2088	386	27	[	[	X
admet-2088	386	28	141,142	141,142	NUM
admet-2088	386	29	]	]	PUNCT
admet-2088	386	30	.	.	PUNCT
admet-2088	387	1	the	the	DET
admet-2088	387	2	qualities	quality	NOUN
admet-2088	387	3	such	such	ADJ
admet-2088	387	4	as	as	ADP
admet-2088	387	5	rapid	rapid	ADJ
admet-2088	387	6	and	and	CCONJ
admet-2088	387	7	green	green	ADJ
admet-2088	387	8	synthesis	synthesis	NOUN
admet-2088	387	9	,	,	PUNCT
admet-2088	387	10	low	low	ADJ
admet-2088	387	11	cost	cost	NOUN
admet-2088	387	12	and	and	CCONJ
admet-2088	387	13	ph	ph	NOUN
admet-2088	387	14	responsiveness	responsiveness	NOUN
admet-2088	387	15	make	make	VERB
admet-2088	387	16	mpn	mpn	NOUN
admet-2088	387	17	a	a	DET
admet-2088	387	18	potential	potential	ADJ
admet-2088	387	19	candidate	candidate	NOUN
admet-2088	387	20	for	for	ADP
admet-2088	387	21	coating	coating	NOUN
admet-2088	387	22	biomedicals	biomedical	NOUN
admet-2088	387	23	[	[	X
admet-2088	387	24	143	143	NUM
admet-2088	387	25	]	]	PUNCT
admet-2088	387	26	.	.	PUNCT
admet-2088	388	1	based	base	VERB
admet-2088	388	2	on	on	ADP
admet-2088	388	3	the	the	DET
admet-2088	388	4	above	above	ADJ
admet-2088	388	5	concept	concept	NOUN
admet-2088	388	6	,	,	PUNCT
admet-2088	388	7	mu	mu	PROPN
admet-2088	388	8	et	et	PROPN
admet-2088	388	9	al	al	PROPN
admet-2088	388	10	.	.	PUNCT
admet-2088	389	1	[	[	X
admet-2088	389	2	144	144	NUM
admet-2088	389	3	]	]	PUNCT
admet-2088	389	4	employed	employ	VERB
admet-2088	389	5	mpn	mpn	NOUN
admet-2088	389	6	to	to	PART
admet-2088	389	7	coat	coat	VERB
admet-2088	389	8	cabazitaxel	cabazitaxel	PROPN
admet-2088	389	9	(	(	PUNCT
admet-2088	389	10	cab@mpn	cab@mpn	NOUN
admet-2088	389	11	)	)	PUNCT
admet-2088	389	12	via	via	ADP
admet-2088	389	13	the	the	DET
admet-2088	389	14	coordinate	coordinate	NOUN
admet-2088	389	15	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	389	16	m.	m.	NOUN
admet-2088	389	17	kulkarni	kulkarni	PROPN
admet-2088	389	18	et	et	PROPN
admet-2088	389	19	al	al	PROPN
admet-2088	389	20	.	.	PROPN
admet-2088	389	21	admet	admet	PROPN
admet-2088	389	22	&	&	CCONJ
admet-2088	389	23	dmpk	dmpk	PROPN
admet-2088	389	24	12(1	12(1	PROPN
admet-2088	389	25	)	)	PUNCT
admet-2088	389	26	(	(	PUNCT
admet-2088	389	27	2024	2024	NUM
admet-2088	389	28	)	)	PUNCT
admet-2088	389	29	107	107	NUM
admet-2088	389	30	-	-	SYM
admet-2088	389	31	150	150	NUM
admet-2088	389	32	122	122	NUM
admet-2088	389	33	reaction	reaction	NOUN
admet-2088	389	34	between	between	ADP
admet-2088	389	35	metal	metal	NOUN
admet-2088	389	36	and	and	CCONJ
admet-2088	389	37	polyphenol	polyphenol	NOUN
admet-2088	389	38	.	.	PUNCT
admet-2088	390	1	the	the	DET
admet-2088	390	2	drug	drug	NOUN
admet-2088	390	3	loading	loading	NOUN
admet-2088	390	4	efficiency	efficiency	NOUN
admet-2088	390	5	was	be	AUX
admet-2088	390	6	found	find	VERB
admet-2088	390	7	to	to	PART
admet-2088	390	8	be	be	AUX
admet-2088	390	9	increased	increase	VERB
admet-2088	390	10	from	from	ADP
admet-2088	390	11	7.56	7.56	NUM
admet-2088	390	12	%	%	NOUN
admet-2088	390	13	to	to	ADP
admet-2088	390	14	9.28	9.28	NUM
admet-2088	390	15	%	%	NOUN
admet-2088	390	16	after	after	ADP
admet-2088	390	17	the	the	DET
admet-2088	390	18	introduction	introduction	NOUN
admet-2088	390	19	of	of	ADP
admet-2088	390	20	chitosan	chitosan	NOUN
admet-2088	390	21	coating	coating	NOUN
admet-2088	390	22	(	(	PUNCT
admet-2088	390	23	cab@mpn	cab@mpn	X
admet-2088	390	24	/	/	SYM
admet-2088	390	25	cs	cs	NOUN
admet-2088	390	26	)	)	PUNCT
admet-2088	390	27	.	.	PUNCT
admet-2088	391	1	the	the	DET
admet-2088	391	2	protonated	protonate	VERB
admet-2088	391	3	amines	amine	NOUN
admet-2088	391	4	and	and	CCONJ
admet-2088	391	5	swelling	swelling	NOUN
admet-2088	391	6	process	process	NOUN
admet-2088	391	7	of	of	ADP
admet-2088	391	8	chitosan	chitosan	NOUN
admet-2088	391	9	led	lead	VERB
admet-2088	391	10	to	to	ADP
admet-2088	391	11	the	the	DET
admet-2088	391	12	faster	fast	ADJ
admet-2088	391	13	release	release	NOUN
admet-2088	391	14	of	of	ADP
admet-2088	391	15	cabazitaxel	cabazitaxel	PROPN
admet-2088	391	16	in	in	ADP
admet-2088	391	17	the	the	DET
admet-2088	391	18	acidic	acidic	ADJ
admet-2088	391	19	environment	environment	NOUN
admet-2088	391	20	of	of	ADP
admet-2088	391	21	melanoma	melanoma	NOUN
admet-2088	391	22	.	.	PUNCT
admet-2088	392	1	the	the	DET
admet-2088	392	2	chitosan	chitosan	NOUN
admet-2088	392	3	coating	coating	NOUN
admet-2088	392	4	provided	provide	VERB
admet-2088	392	5	positive	positive	ADJ
admet-2088	392	6	charges	charge	NOUN
admet-2088	392	7	to	to	ADP
admet-2088	392	8	the	the	DET
admet-2088	392	9	surface	surface	NOUN
admet-2088	392	10	of	of	ADP
admet-2088	392	11	nps	nps	PROPN
admet-2088	392	12	,	,	PUNCT
admet-2088	392	13	which	which	PRON
admet-2088	392	14	improved	improve	VERB
admet-2088	392	15	internalization	internalization	NOUN
admet-2088	392	16	in	in	ADP
admet-2088	392	17	b16f10	b16f10	ADJ
admet-2088	392	18	cells	cell	NOUN
admet-2088	392	19	and	and	CCONJ
admet-2088	392	20	then	then	ADV
admet-2088	392	21	cab@mpn	cab@mpn	NUM
admet-2088	392	22	/	/	SYM
admet-2088	392	23	cs	cs	PROPN
admet-2088	392	24	escaped	escape	VERB
admet-2088	392	25	lysosomes	lysosome	NOUN
admet-2088	392	26	via	via	ADP
admet-2088	392	27	proton	proton	NOUN
admet-2088	392	28	sponge	sponge	NOUN
admet-2088	392	29	effect	effect	NOUN
admet-2088	392	30	.	.	PUNCT
admet-2088	393	1	now	now	ADV
admet-2088	393	2	,	,	PUNCT
admet-2088	393	3	the	the	DET
admet-2088	393	4	released	release	VERB
admet-2088	393	5	cabazitaxel	cabazitaxel	PROPN
admet-2088	393	6	acted	act	VERB
admet-2088	393	7	on	on	ADP
admet-2088	393	8	microtubules	microtubule	NOUN
admet-2088	393	9	and	and	CCONJ
admet-2088	393	10	induced	induce	VERB
admet-2088	393	11	cell	cell	NOUN
admet-2088	393	12	apoptosis	apoptosis	NOUN
admet-2088	393	13	.	.	PUNCT
admet-2088	394	1	in	in	ADP
admet-2088	394	2	vivo	vivo	NOUN
admet-2088	394	3	study	study	NOUN
admet-2088	394	4	showed	show	VERB
admet-2088	394	5	that	that	SCONJ
admet-2088	394	6	the	the	DET
admet-2088	394	7	cab@mpn	cab@mpn	PROPN
admet-2088	394	8	/	/	SYM
admet-2088	394	9	cs	cs	PROPN
admet-2088	394	10	nps	nps	PROPN
admet-2088	394	11	have	have	VERB
admet-2088	394	12	longer	long	ADJ
admet-2088	394	13	retention	retention	VERB
admet-2088	394	14	time	time	NOUN
admet-2088	394	15	in	in	ADP
admet-2088	394	16	tumour	tumour	ADJ
admet-2088	394	17	tissues	tissue	NOUN
admet-2088	394	18	and	and	CCONJ
admet-2088	394	19	significantly	significantly	ADV
admet-2088	394	20	reduced	reduce	VERB
admet-2088	394	21	tumour	tumour	NOUN
admet-2088	394	22	growth	growth	NOUN
admet-2088	394	23	by	by	ADP
admet-2088	394	24	upregulating	upregulating	ADJ
admet-2088	394	25	tunel	tunel	NOUN
admet-2088	394	26	expression	expression	NOUN
admet-2088	394	27	and	and	CCONJ
admet-2088	394	28	downregulating	downregulating	NOUN
admet-2088	394	29	k167	k167	PROPN
admet-2088	394	30	and	and	CCONJ
admet-2088	394	31	cd31	cd31	PROPN
admet-2088	394	32	expression	expression	NOUN
admet-2088	394	33	.	.	PUNCT
admet-2088	395	1	on	on	ADP
admet-2088	395	2	a	a	DET
admet-2088	395	3	similar	similar	ADJ
admet-2088	395	4	concept	concept	NOUN
admet-2088	395	5	,	,	PUNCT
admet-2088	395	6	a	a	DET
admet-2088	395	7	nano	nano	NOUN
admet-2088	395	8	-	-	PUNCT
admet-2088	395	9	delivery	delivery	NOUN
admet-2088	395	10	system	system	NOUN
admet-2088	395	11	(	(	PUNCT
admet-2088	395	12	nanocomposite	nanocomposite	NOUN
admet-2088	395	13	)	)	PUNCT
admet-2088	395	14	comprised	comprise	VERB
admet-2088	395	15	of	of	ADP
admet-2088	395	16	iron	iron	NOUN
admet-2088	395	17	(	(	PUNCT
admet-2088	395	18	fe+3	fe+3	PROPN
admet-2088	395	19	)	)	PUNCT
admet-2088	395	20	based	base	VERB
admet-2088	395	21	mpn	mpn	NOUN
admet-2088	395	22	with	with	ADP
admet-2088	395	23	gallic	gallic	NOUN
admet-2088	395	24	acid	acid	NOUN
admet-2088	395	25	grafted	graft	VERB
admet-2088	395	26	ha	ha	INTJ
admet-2088	395	27	(	(	PUNCT
admet-2088	395	28	ce6@ha	ce6@ha	PROPN
admet-2088	395	29	-	-	PUNCT
admet-2088	395	30	ga	ga	PROPN
admet-2088	395	31	nps	nps	PROPN
admet-2088	395	32	)	)	PUNCT
admet-2088	395	33	was	be	AUX
admet-2088	395	34	developed	develop	VERB
admet-2088	395	35	.	.	PUNCT
admet-2088	396	1	here	here	ADV
admet-2088	396	2	,	,	PUNCT
admet-2088	396	3	chlorin	chlorin	NOUN
admet-2088	396	4	e6	e6	PROPN
admet-2088	396	5	(	(	PUNCT
admet-2088	396	6	ce6	ce6	PROPN
admet-2088	396	7	)	)	PUNCT
admet-2088	396	8	,	,	PUNCT
admet-2088	396	9	a	a	DET
admet-2088	396	10	second	second	ADJ
admet-2088	396	11	-	-	PUNCT
admet-2088	396	12	generation	generation	NOUN
admet-2088	396	13	photosensitizer	photosensitizer	NOUN
admet-2088	396	14	,	,	PUNCT
admet-2088	396	15	was	be	AUX
admet-2088	396	16	used	use	VERB
admet-2088	396	17	.	.	PUNCT
admet-2088	397	1	the	the	DET
admet-2088	397	2	intracellular	intracellular	ADJ
admet-2088	397	3	ros	ros	PROPN
admet-2088	397	4	generation	generation	NOUN
admet-2088	397	5	for	for	ADP
admet-2088	397	6	ce6@ha	ce6@ha	PROPN
admet-2088	397	7	-	-	PUNCT
admet-2088	397	8	ga	ga	PROPN
admet-2088	397	9	nps	nps	PROPN
admet-2088	397	10	via	via	ADP
admet-2088	397	11	cdt	cdt	PROPN
admet-2088	397	12	and	and	CCONJ
admet-2088	397	13	pdt	pdt	PROPN
admet-2088	397	14	was	be	AUX
admet-2088	397	15	higher	high	ADJ
admet-2088	397	16	than	than	ADP
admet-2088	397	17	ce6	ce6	ADV
admet-2088	397	18	-	-	PUNCT
admet-2088	397	19	induced	induce	VERB
admet-2088	397	20	pdt	pdt	NOUN
admet-2088	397	21	and	and	CCONJ
admet-2088	397	22	ce6@hsf	ce6@hsf	NOUN
admet-2088	397	23	nps	nps	PROPN
admet-2088	397	24	-	-	PUNCT
admet-2088	397	25	induced	induce	VERB
admet-2088	397	26	cdt	cdt	PROPN
admet-2088	397	27	.	.	PUNCT
admet-2088	398	1	both	both	PRON
admet-2088	398	2	in	in	ADP
admet-2088	398	3	vitro	vitro	X
admet-2088	398	4	and	and	CCONJ
admet-2088	398	5	in	in	ADP
admet-2088	398	6	vivo	vivo	ADJ
admet-2088	398	7	studies	study	NOUN
admet-2088	398	8	revealed	reveal	VERB
admet-2088	398	9	that	that	SCONJ
admet-2088	398	10	ce6@ha	ce6@ha	PROPN
admet-2088	398	11	-	-	PUNCT
admet-2088	398	12	ga	ga	PROPN
admet-2088	398	13	nps	nps	PROPN
admet-2088	398	14	had	have	VERB
admet-2088	398	15	the	the	DET
admet-2088	398	16	best	good	ADJ
admet-2088	398	17	anti	anti	ADJ
admet-2088	398	18	-	-	ADJ
admet-2088	398	19	melanoma	melanoma	ADJ
admet-2088	398	20	effect	effect	NOUN
admet-2088	398	21	[	[	X
admet-2088	398	22	145	145	NUM
admet-2088	398	23	]	]	PUNCT
admet-2088	398	24	.	.	PUNCT
admet-2088	399	1	most	most	ADV
admet-2088	399	2	recently	recently	ADV
admet-2088	399	3	,	,	PUNCT
admet-2088	399	4	li	li	PROPN
admet-2088	399	5	et	et	PROPN
admet-2088	399	6	al	al	PROPN
admet-2088	399	7	.	.	PUNCT
admet-2088	400	1	[	[	X
admet-2088	400	2	146	146	NUM
admet-2088	400	3	]	]	PUNCT
admet-2088	400	4	successfully	successfully	ADV
admet-2088	400	5	developed	develop	VERB
admet-2088	400	6	an	an	DET
admet-2088	400	7	injectable	injectable	ADJ
admet-2088	400	8	nanocomposite	nanocomposite	NOUN
admet-2088	400	9	alginate	alginate	NOUN
admet-2088	400	10	-	-	PUNCT
admet-2088	400	11	graft	graft	NOUN
admet-2088	400	12	-	-	PUNCT
admet-2088	400	13	dopamine	dopamine	NOUN
admet-2088	400	14	(	(	PUNCT
admet-2088	400	15	sd	sd	NOUN
admet-2088	400	16	)	)	PUNCT
admet-2088	400	17	hydrogel	hydrogel	NOUN
admet-2088	400	18	with	with	ADP
admet-2088	400	19	entrapped	entrap	VERB
admet-2088	400	20	biomimetic	biomimetic	ADJ
admet-2088	400	21	polydopamine	polydopamine	NOUN
admet-2088	400	22	-	-	PUNCT
admet-2088	400	23	fe(iii)-doxorubicin	fe(iii)-doxorubicin	ADJ
admet-2088	400	24	nps	nps	PROPN
admet-2088	400	25	(	(	PUNCT
admet-2088	400	26	pfd	pfd	PROPN
admet-2088	400	27	nps	nps	PROPN
admet-2088	400	28	)	)	PUNCT
admet-2088	400	29	.	.	PUNCT
admet-2088	401	1	the	the	DET
admet-2088	401	2	nanocomposite	nanocomposite	PROPN
admet-2088	401	3	hydrogel	hydrogel	NOUN
admet-2088	401	4	was	be	AUX
admet-2088	401	5	capable	capable	ADJ
admet-2088	401	6	of	of	ADP
admet-2088	401	7	delivering	deliver	VERB
admet-2088	401	8	doxorubicin	doxorubicin	NOUN
admet-2088	401	9	precisely	precisely	ADV
admet-2088	401	10	to	to	ADP
admet-2088	401	11	the	the	DET
admet-2088	401	12	tumour	tumour	NOUN
admet-2088	401	13	site	site	NOUN
admet-2088	401	14	and	and	CCONJ
admet-2088	401	15	thereafter	thereafter	ADV
admet-2088	401	16	pdtbased	pdtbased	ADJ
admet-2088	401	17	killing	killing	NOUN
admet-2088	401	18	of	of	ADP
admet-2088	401	19	cancer	cancer	NOUN
admet-2088	401	20	cells	cell	NOUN
admet-2088	401	21	mediated	mediate	VERB
admet-2088	401	22	by	by	ADP
admet-2088	401	23	pfd	pfd	PROPN
admet-2088	401	24	that	that	PRON
admet-2088	401	25	converted	convert	VERB
admet-2088	401	26	nir	nir	ADJ
admet-2088	401	27	irradiation	irradiation	NOUN
admet-2088	401	28	into	into	ADP
admet-2088	401	29	heat	heat	NOUN
admet-2088	401	30	energy	energy	NOUN
admet-2088	401	31	.	.	PUNCT
admet-2088	402	1	in	in	ADP
admet-2088	402	2	addition	addition	NOUN
admet-2088	402	3	,	,	PUNCT
admet-2088	402	4	pfd	pfd	PROPN
admet-2088	402	5	can	can	AUX
admet-2088	402	6	catalyze	catalyze	VERB
admet-2088	402	7	excessive	excessive	ADJ
admet-2088	402	8	endogenous	endogenous	ADJ
admet-2088	402	9	h2o2	h2o2	NOUN
admet-2088	402	10	into	into	ADP
admet-2088	402	11	o2	o2	PROPN
admet-2088	402	12	to	to	PART
admet-2088	402	13	relieve	relieve	VERB
admet-2088	402	14	tumour	tumour	NOUN
admet-2088	402	15	hypoxia	hypoxia	NOUN
admet-2088	402	16	.	.	PUNCT
admet-2088	403	1	thus	thus	ADV
admet-2088	403	2	,	,	PUNCT
admet-2088	403	3	this	this	DET
admet-2088	403	4	nanocomposite	nanocomposite	NOUN
admet-2088	403	5	provided	provide	VERB
admet-2088	403	6	synergism	synergism	NOUN
admet-2088	403	7	through	through	ADP
admet-2088	403	8	pdt	pdt	PROPN
admet-2088	403	9	,	,	PUNCT
admet-2088	403	10	chemotherapy	chemotherapy	NOUN
admet-2088	403	11	and	and	CCONJ
admet-2088	403	12	nanozyme	nanozyme	NOUN
admet-2088	403	13	therapy	therapy	NOUN
admet-2088	403	14	.	.	PUNCT
admet-2088	404	1	both	both	PRON
admet-2088	404	2	in	in	ADP
admet-2088	404	3	vitro	vitro	X
admet-2088	404	4	and	and	CCONJ
admet-2088	404	5	in	in	ADP
admet-2088	404	6	vivo	vivo	ADJ
admet-2088	404	7	studies	study	NOUN
admet-2088	404	8	revealed	reveal	VERB
admet-2088	404	9	that	that	SCONJ
admet-2088	404	10	nanocomposite	nanocomposite	PROPN
admet-2088	404	11	hydrogel	hydrogel	NOUN
admet-2088	404	12	can	can	AUX
admet-2088	404	13	significantly	significantly	ADV
admet-2088	404	14	inhibit	inhibit	VERB
admet-2088	404	15	the	the	DET
admet-2088	404	16	proliferation	proliferation	NOUN
admet-2088	404	17	and	and	CCONJ
admet-2088	404	18	migration	migration	NOUN
admet-2088	404	19	of	of	ADP
admet-2088	404	20	melanoma	melanoma	NOUN
admet-2088	404	21	cells	cell	NOUN
admet-2088	404	22	.	.	PUNCT
admet-2088	405	1	in	in	ADP
admet-2088	405	2	addition	addition	NOUN
admet-2088	405	3	,	,	PUNCT
admet-2088	405	4	this	this	DET
admet-2088	405	5	hydrogel	hydrogel	NOUN
admet-2088	405	6	can	can	AUX
admet-2088	405	7	significantly	significantly	ADV
admet-2088	405	8	enhance	enhance	VERB
admet-2088	405	9	epidermal	epidermal	ADJ
admet-2088	405	10	regeneration	regeneration	NOUN
admet-2088	405	11	through	through	ADP
admet-2088	405	12	bactericidal	bactericidal	NOUN
admet-2088	405	13	and	and	CCONJ
admet-2088	405	14	ros	ros	NOUN
admet-2088	405	15	scavenging	scavenging	NOUN
admet-2088	405	16	effects	effect	NOUN
admet-2088	405	17	and	and	CCONJ
admet-2088	405	18	increase	increase	VERB
admet-2088	405	19	the	the	DET
admet-2088	405	20	proliferation	proliferation	NOUN
admet-2088	405	21	and	and	CCONJ
admet-2088	405	22	migration	migration	NOUN
admet-2088	405	23	of	of	ADP
admet-2088	405	24	cells	cell	NOUN
admet-2088	405	25	.	.	PUNCT
admet-2088	406	1	carbon	carbon	NOUN
admet-2088	406	2	-	-	PUNCT
admet-2088	406	3	based	base	VERB
admet-2088	406	4	nms	nms	PROPN
admet-2088	406	5	sumio	sumio	PROPN
admet-2088	406	6	iijima	iijima	PROPN
admet-2088	406	7	of	of	ADP
admet-2088	406	8	japan	japan	PROPN
admet-2088	406	9	first	first	ADV
admet-2088	406	10	invented	invent	VERB
admet-2088	406	11	carbon	carbon	NOUN
admet-2088	406	12	nanotubes	nanotube	NOUN
admet-2088	406	13	(	(	PUNCT
admet-2088	406	14	cnts	cnt	NOUN
admet-2088	406	15	)	)	PUNCT
admet-2088	406	16	in	in	ADP
admet-2088	406	17	1991	1991	NUM
admet-2088	406	18	[	[	X
admet-2088	406	19	147	147	NUM
admet-2088	406	20	]	]	PUNCT
admet-2088	406	21	.	.	PUNCT
admet-2088	407	1	these	these	PRON
admet-2088	407	2	comprise	comprise	VERB
admet-2088	407	3	big	big	ADJ
admet-2088	407	4	cylindrical	cylindrical	ADJ
admet-2088	407	5	molecules	molecule	NOUN
admet-2088	407	6	with	with	ADP
admet-2088	407	7	a	a	DET
admet-2088	407	8	hexagonal	hexagonal	ADJ
admet-2088	407	9	arrangement	arrangement	NOUN
admet-2088	407	10	of	of	ADP
admet-2088	407	11	sp2	sp2	NOUN
admet-2088	407	12	hybridized	hybridize	VERB
admet-2088	407	13	carbon	carbon	NOUN
admet-2088	407	14	atoms	atom	NOUN
admet-2088	407	15	.	.	PUNCT
admet-2088	408	1	the	the	DET
admet-2088	408	2	cnts	cnts	PROPN
admet-2088	408	3	showed	show	VERB
admet-2088	408	4	exceptional	exceptional	ADJ
admet-2088	408	5	tensile	tensile	NOUN
admet-2088	408	6	strength	strength	NOUN
admet-2088	408	7	,	,	PUNCT
admet-2088	408	8	higher	high	ADJ
admet-2088	408	9	conductivity	conductivity	NOUN
admet-2088	408	10	,	,	PUNCT
admet-2088	408	11	and	and	CCONJ
admet-2088	408	12	excellent	excellent	ADJ
admet-2088	408	13	thermal	thermal	ADJ
admet-2088	408	14	and	and	CCONJ
admet-2088	408	15	chemical	chemical	NOUN
admet-2088	408	16	stabilities	stability	NOUN
admet-2088	408	17	[	[	X
admet-2088	408	18	148	148	NUM
admet-2088	408	19	-	-	SYM
admet-2088	408	20	150	150	NUM
admet-2088	408	21	]	]	PUNCT
admet-2088	408	22	.	.	PUNCT
admet-2088	409	1	cnts	cnt	NOUN
admet-2088	409	2	are	be	AUX
admet-2088	409	3	made	make	VERB
admet-2088	409	4	up	up	ADP
admet-2088	409	5	of	of	ADP
admet-2088	409	6	the	the	DET
admet-2088	409	7	rolling	rolling	NOUN
admet-2088	409	8	of	of	ADP
admet-2088	409	9	a	a	DET
admet-2088	409	10	single	single	ADJ
admet-2088	409	11	-	-	PUNCT
admet-2088	409	12	walled	wall	VERB
admet-2088	409	13	graphene	graphene	NOUN
admet-2088	409	14	sheet	sheet	NOUN
admet-2088	409	15	called	call	VERB
admet-2088	409	16	single	single	ADJ
admet-2088	409	17	-	-	PUNCT
admet-2088	409	18	walled	wall	VERB
admet-2088	409	19	cnts	cnt	NOUN
admet-2088	409	20	(	(	PUNCT
admet-2088	409	21	swcnts	swcnt	NOUN
admet-2088	409	22	)	)	PUNCT
admet-2088	409	23	,	,	PUNCT
admet-2088	409	24	whereas	whereas	SCONJ
admet-2088	409	25	the	the	DET
admet-2088	409	26	rolling	rolling	NOUN
admet-2088	409	27	up	up	ADP
admet-2088	409	28	of	of	ADP
admet-2088	409	29	more	more	ADJ
admet-2088	409	30	than	than	ADP
admet-2088	409	31	one	one	NUM
admet-2088	409	32	graphene	graphene	NOUN
admet-2088	409	33	sheet	sheet	NOUN
admet-2088	409	34	constitutes	constitute	VERB
admet-2088	409	35	multi	multi	ADJ
admet-2088	409	36	-	-	ADJ
admet-2088	409	37	walled	walled	ADJ
admet-2088	409	38	cnts	cnt	NOUN
admet-2088	409	39	(	(	PUNCT
admet-2088	409	40	mwcnts	mwcnt	NOUN
admet-2088	409	41	)	)	PUNCT
admet-2088	409	42	.	.	PUNCT
admet-2088	410	1	swcnts	swcnt	NOUN
admet-2088	410	2	are	be	AUX
admet-2088	410	3	preferred	prefer	VERB
admet-2088	410	4	as	as	ADP
admet-2088	410	5	drug	drug	NOUN
admet-2088	410	6	delivery	delivery	NOUN
admet-2088	410	7	vehicles	vehicle	NOUN
admet-2088	410	8	due	due	ADP
admet-2088	410	9	to	to	ADP
admet-2088	410	10	their	their	PRON
admet-2088	410	11	distinct	distinct	ADJ
admet-2088	410	12	wall	wall	NOUN
admet-2088	410	13	and	and	CCONJ
admet-2088	410	14	small	small	ADJ
admet-2088	410	15	width	width	NOUN
admet-2088	410	16	.	.	PUNCT
admet-2088	411	1	however	however	ADV
admet-2088	411	2	,	,	PUNCT
admet-2088	411	3	mwcnts	mwcnt	NOUN
admet-2088	411	4	are	be	AUX
admet-2088	411	5	characterized	characterize	VERB
admet-2088	411	6	by	by	ADP
admet-2088	411	7	defects	defect	NOUN
admet-2088	411	8	in	in	ADP
admet-2088	411	9	their	their	PRON
admet-2088	411	10	structure	structure	NOUN
admet-2088	411	11	,	,	PUNCT
admet-2088	411	12	resulting	result	VERB
admet-2088	411	13	in	in	ADP
admet-2088	411	14	poor	poor	ADJ
admet-2088	411	15	stability	stability	NOUN
admet-2088	411	16	,	,	PUNCT
admet-2088	411	17	but	but	CCONJ
admet-2088	411	18	on	on	ADP
admet-2088	411	19	the	the	DET
admet-2088	411	20	other	other	ADJ
admet-2088	411	21	hand	hand	NOUN
admet-2088	411	22	,	,	PUNCT
admet-2088	411	23	they	they	PRON
admet-2088	411	24	provide	provide	VERB
admet-2088	411	25	opportunities	opportunity	NOUN
admet-2088	411	26	for	for	ADP
admet-2088	411	27	modification	modification	NOUN
admet-2088	412	1	[	[	X
admet-2088	412	2	151	151	NUM
admet-2088	412	3	]	]	SYM
admet-2088	412	4	.	.	PUNCT
admet-2088	413	1	drug	drug	NOUN
admet-2088	413	2	molecules	molecule	NOUN
admet-2088	413	3	can	can	AUX
admet-2088	413	4	be	be	AUX
admet-2088	413	5	loaded	load	VERB
admet-2088	413	6	onto	onto	ADP
admet-2088	413	7	cnts	cnt	NOUN
admet-2088	413	8	through	through	ADP
admet-2088	413	9	the	the	DET
admet-2088	413	10	following	follow	VERB
admet-2088	413	11	interaction	interaction	NOUN
admet-2088	413	12	:	:	PUNCT
admet-2088	413	13	entrapments	entrapment	NOUN
admet-2088	413	14	inside	inside	ADP
admet-2088	413	15	cnt	cnt	ADJ
admet-2088	413	16	channels	channel	NOUN
admet-2088	413	17	or	or	CCONJ
admet-2088	413	18	within	within	ADP
admet-2088	413	19	cnt	cnt	PROPN
admet-2088	413	20	bundle	bundle	NOUN
admet-2088	413	21	or	or	CCONJ
admet-2088	413	22	cnt	cnt	PROPN
admet-2088	413	23	mesh	mesh	NOUN
admet-2088	413	24	and	and	CCONJ
admet-2088	413	25	attachment	attachment	NOUN
admet-2088	413	26	of	of	ADP
admet-2088	413	27	the	the	DET
admet-2088	413	28	drug	drug	NOUN
admet-2088	413	29	molecules	molecule	NOUN
admet-2088	413	30	to	to	ADP
admet-2088	413	31	the	the	DET
admet-2088	413	32	outer	outer	ADJ
admet-2088	413	33	wall	wall	NOUN
admet-2088	413	34	of	of	ADP
admet-2088	413	35	cnt	cnt	PROPN
admet-2088	413	36	through	through	ADP
admet-2088	413	37	functional	functional	ADJ
admet-2088	413	38	groups	group	NOUN
admet-2088	413	39	[	[	X
admet-2088	413	40	152	152	NUM
admet-2088	413	41	]	]	PUNCT
admet-2088	413	42	.	.	PUNCT
admet-2088	414	1	thus	thus	ADV
admet-2088	414	2	,	,	PUNCT
admet-2088	414	3	cnts	cnt	NOUN
admet-2088	414	4	are	be	AUX
admet-2088	414	5	widely	widely	ADV
admet-2088	414	6	researched	research	VERB
admet-2088	414	7	as	as	ADP
admet-2088	414	8	an	an	DET
admet-2088	414	9	effective	effective	ADJ
admet-2088	414	10	delivery	delivery	NOUN
admet-2088	414	11	vehicle	vehicle	NOUN
admet-2088	414	12	for	for	ADP
admet-2088	414	13	a	a	DET
admet-2088	414	14	variety	variety	NOUN
admet-2088	414	15	of	of	ADP
admet-2088	414	16	drugs	drug	NOUN
admet-2088	414	17	and	and	CCONJ
admet-2088	414	18	photosensitizing	photosensitize	VERB
admet-2088	414	19	agents	agent	NOUN
admet-2088	414	20	[	[	X
admet-2088	414	21	153	153	NUM
admet-2088	414	22	]	]	PUNCT
admet-2088	414	23	.	.	PUNCT
admet-2088	415	1	a	a	DET
admet-2088	415	2	versatile	versatile	ADJ
admet-2088	415	3	swcnts	swcnt	NOUN
admet-2088	415	4	-	-	PUNCT
admet-2088	415	5	based	base	VERB
admet-2088	415	6	nanovector	nanovector	NOUN
admet-2088	415	7	was	be	AUX
admet-2088	415	8	developed	develop	VERB
admet-2088	415	9	for	for	ADP
admet-2088	415	10	the	the	DET
admet-2088	415	11	delivery	delivery	NOUN
admet-2088	415	12	of	of	ADP
admet-2088	415	13	doxorubicin	doxorubicin	PROPN
admet-2088	415	14	to	to	PART
admet-2088	415	15	treat	treat	VERB
admet-2088	415	16	melanoma	melanoma	NOUN
admet-2088	415	17	.	.	PUNCT
admet-2088	416	1	here	here	ADV
admet-2088	416	2	,	,	PUNCT
admet-2088	416	3	the	the	DET
admet-2088	416	4	swcnts	swcnt	NOUN
admet-2088	416	5	were	be	AUX
admet-2088	416	6	modified	modify	VERB
admet-2088	416	7	to	to	PART
admet-2088	416	8	conjugate	conjugate	VERB
admet-2088	416	9	a	a	DET
admet-2088	416	10	doxorubicin	doxorubicin	PROPN
admet-2088	416	11	prodrug	prodrug	NOUN
admet-2088	416	12	(	(	PUNCT
admet-2088	416	13	swcnt	swcnt	ADP
admet-2088	416	14	-	-	PUNCT
admet-2088	416	15	dox	dox	NOUN
admet-2088	416	16	)	)	PUNCT
admet-2088	416	17	via	via	ADP
admet-2088	416	18	a	a	DET
admet-2088	416	19	carbamate	carbamate	NOUN
admet-2088	416	20	linker	linker	NOUN
admet-2088	416	21	,	,	PUNCT
admet-2088	416	22	which	which	PRON
admet-2088	416	23	cleaves	cleave	VERB
admet-2088	416	24	enzymatically	enzymatically	ADV
admet-2088	416	25	to	to	PART
admet-2088	416	26	cause	cause	VERB
admet-2088	416	27	temporal	temporal	ADJ
admet-2088	416	28	release	release	NOUN
admet-2088	416	29	of	of	ADP
admet-2088	416	30	the	the	DET
admet-2088	416	31	active	active	ADJ
admet-2088	416	32	drug	drug	NOUN
admet-2088	416	33	.	.	PUNCT
admet-2088	417	1	the	the	DET
admet-2088	417	2	resulting	result	VERB
admet-2088	417	3	nanovector	nanovector	NOUN
admet-2088	417	4	induced	induce	VERB
admet-2088	417	5	time	time	NOUN
admet-2088	417	6	-	-	PUNCT
admet-2088	417	7	dependent	dependent	ADJ
admet-2088	417	8	death	death	NOUN
admet-2088	417	9	of	of	ADP
admet-2088	417	10	b16	b16	PROPN
admet-2088	417	11	-	-	PUNCT
admet-2088	417	12	f10	f10	NOUN
admet-2088	417	13	melanoma	melanoma	NOUN
admet-2088	417	14	cells	cell	NOUN
admet-2088	417	15	in	in	ADP
admet-2088	417	16	vitro	vitro	VERB
admet-2088	417	17	.	.	PUNCT
admet-2088	418	1	the	the	DET
admet-2088	418	2	swcnt	swcnt	PROPN
admet-2088	418	3	-	-	PUNCT
admet-2088	418	4	dox	dox	ADJ
admet-2088	418	5	nps	nps	PROPN
admet-2088	418	6	internalized	internalize	VERB
admet-2088	418	7	immediately	immediately	ADV
admet-2088	418	8	into	into	ADP
admet-2088	418	9	the	the	DET
admet-2088	418	10	lysosome	lysosome	NOUN
admet-2088	418	11	of	of	ADP
admet-2088	418	12	melanoma	melanoma	NOUN
admet-2088	418	13	cells	cell	NOUN
admet-2088	418	14	and	and	CCONJ
admet-2088	418	15	were	be	AUX
admet-2088	418	16	retained	retain	VERB
admet-2088	418	17	subcellularly	subcellularly	ADV
admet-2088	418	18	for	for	ADP
admet-2088	418	19	over	over	ADP
admet-2088	418	20	24	24	NUM
admet-2088	418	21	h.	h.	NOUN
admet-2088	418	22	in	in	ADP
admet-2088	418	23	vivo	vivo	ADJ
admet-2088	418	24	melanoma	melanoma	NOUN
admet-2088	418	25	model	model	NOUN
admet-2088	418	26	treated	treat	VERB
admet-2088	418	27	with	with	ADP
admet-2088	418	28	swcnt	swcnt	ADJ
admet-2088	418	29	-	-	PUNCT
admet-2088	418	30	dox	dox	ADJ
admet-2088	418	31	nanovector	nanovector	NOUN
admet-2088	418	32	ceased	cease	VERB
admet-2088	418	33	the	the	DET
admet-2088	418	34	tumour	tumour	NOUN
admet-2088	418	35	growth	growth	NOUN
admet-2088	418	36	without	without	ADP
admet-2088	418	37	producing	produce	VERB
admet-2088	418	38	systemic	systemic	ADJ
admet-2088	418	39	side	side	NOUN
admet-2088	418	40	effects	effect	NOUN
admet-2088	418	41	associated	associate	VERB
admet-2088	418	42	with	with	ADP
admet-2088	418	43	doxorubicin	doxorubicin	PROPN
admet-2088	419	1	[	[	X
admet-2088	419	2	154	154	NUM
admet-2088	419	3	]	]	PUNCT
admet-2088	419	4	.	.	PUNCT
admet-2088	420	1	low	low	ADJ
admet-2088	420	2	-	-	PUNCT
admet-2088	420	3	intensity	intensity	NOUN
admet-2088	420	4	ultrasound	ultrasound	NOUN
admet-2088	420	5	irradiation	irradiation	NOUN
admet-2088	420	6	with	with	ADP
admet-2088	420	7	sonosensitizer	sonosensitizer	NOUN
admet-2088	420	8	has	have	AUX
admet-2088	420	9	shown	show	VERB
admet-2088	420	10	exceptional	exceptional	ADJ
admet-2088	420	11	advantages	advantage	NOUN
admet-2088	420	12	for	for	ADP
admet-2088	420	13	cancer	cancer	NOUN
admet-2088	420	14	therapy	therapy	NOUN
admet-2088	420	15	due	due	ADP
admet-2088	420	16	to	to	ADP
admet-2088	420	17	its	its	PRON
admet-2088	420	18	advantages	advantage	NOUN
admet-2088	420	19	,	,	PUNCT
admet-2088	420	20	including	include	VERB
admet-2088	420	21	penetration	penetration	NOUN
admet-2088	420	22	to	to	ADP
admet-2088	420	23	deeper	deep	ADJ
admet-2088	420	24	tumours	tumour	NOUN
admet-2088	420	25	,	,	PUNCT
admet-2088	420	26	invasiveness	invasiveness	ADJ
admet-2088	420	27	,	,	PUNCT
admet-2088	420	28	and	and	CCONJ
admet-2088	420	29	targeted	target	VERB
admet-2088	420	30	uptake	uptake	ADJ
admet-2088	420	31	without	without	ADP
admet-2088	420	32	serious	serious	ADJ
admet-2088	420	33	side	side	NOUN
admet-2088	420	34	effects	effect	NOUN
admet-2088	420	35	compared	compare	VERB
admet-2088	420	36	to	to	ADP
admet-2088	420	37	other	other	ADJ
admet-2088	420	38	cancer	cancer	NOUN
admet-2088	420	39	therapies	therapy	NOUN
admet-2088	420	40	.	.	PUNCT
admet-2088	421	1	based	base	VERB
admet-2088	421	2	on	on	ADP
admet-2088	421	3	this	this	PRON
admet-2088	421	4	,	,	PUNCT
admet-2088	421	5	a	a	DET
admet-2088	421	6	nanocomposite	nanocomposite	NOUN
admet-2088	421	7	comprised	comprise	VERB
admet-2088	421	8	admet	admet	PROPN
admet-2088	421	9	&	&	CCONJ
admet-2088	421	10	dmpk	dmpk	PROPN
admet-2088	421	11	12(1	12(1	PROPN
admet-2088	421	12	)	)	PUNCT
admet-2088	421	13	(	(	PUNCT
admet-2088	421	14	2024	2024	NUM
admet-2088	421	15	)	)	PUNCT
admet-2088	421	16	107	107	NUM
admet-2088	421	17	-	-	SYM
admet-2088	421	18	150	150	NUM
admet-2088	421	19	nanomaterial	nanomaterial	NOUN
admet-2088	421	20	-	-	PUNCT
admet-2088	421	21	based	base	VERB
admet-2088	421	22	drug	drug	NOUN
admet-2088	421	23	delivery	delivery	NOUN
admet-2088	421	24	systems	system	NOUN
admet-2088	421	25	for	for	ADP
admet-2088	421	26	melanoma	melanoma	NOUN
admet-2088	421	27	therapy	therapy	NOUN
admet-2088	421	28	doi	doi	NOUN
admet-2088	421	29	:	:	PUNCT
admet-2088	421	30	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	421	31	123	123	NUM
admet-2088	421	32	of	of	ADP
admet-2088	421	33	polypyrrole	polypyrrole	NOUN
admet-2088	421	34	(	(	PUNCT
admet-2088	421	35	sonosensitizer)-coated	sonosensitizer)-coate	VERB
admet-2088	421	36	mwcnts	mwcnt	NOUN
admet-2088	421	37	(	(	PUNCT
admet-2088	421	38	pp	pp	ADP
admet-2088	421	39	-	-	PUNCT
admet-2088	421	40	mwcnts	mwcnt	NOUN
admet-2088	421	41	)	)	PUNCT
admet-2088	421	42	was	be	AUX
admet-2088	421	43	fabricated	fabricate	VERB
admet-2088	421	44	and	and	CCONJ
admet-2088	421	45	employed	employ	VERB
admet-2088	421	46	in	in	ADP
admet-2088	421	47	melanoma	melanoma	NOUN
admet-2088	421	48	therapy	therapy	NOUN
admet-2088	421	49	.	.	PUNCT
admet-2088	422	1	in	in	ADP
admet-2088	422	2	vitro	vitro	X
admet-2088	422	3	investigation	investigation	NOUN
admet-2088	422	4	on	on	ADP
admet-2088	422	5	the	the	DET
admet-2088	422	6	nanocomposite	nanocomposite	NOUN
admet-2088	422	7	showed	show	VERB
admet-2088	422	8	a	a	DET
admet-2088	422	9	concentration	concentration	NOUN
admet-2088	422	10	-	-	PUNCT
admet-2088	422	11	dependent	dependent	ADJ
admet-2088	422	12	cytotoxicity	cytotoxicity	NOUN
admet-2088	422	13	with	with	ADP
admet-2088	422	14	a	a	DET
admet-2088	422	15	cell	cell	NOUN
admet-2088	422	16	viability	viability	NOUN
admet-2088	422	17	of	of	ADP
admet-2088	422	18	8.9	8.9	NUM
admet-2088	422	19	%	%	NOUN
admet-2088	422	20	in	in	ADP
admet-2088	422	21	multi	multi	ADJ
admet-2088	422	22	-	-	ADJ
admet-2088	422	23	step	step	ADJ
admet-2088	422	24	ultrasound	ultrasound	NOUN
admet-2088	422	25	irradiation	irradiation	NOUN
admet-2088	422	26	.	.	PUNCT
admet-2088	423	1	this	this	DET
admet-2088	423	2	four	four	NUM
admet-2088	423	3	-	-	PUNCT
admet-2088	423	4	step	step	NOUN
admet-2088	423	5	sdt	sdt	PROPN
admet-2088	423	6	therapy	therapy	NOUN
admet-2088	423	7	resulted	result	VERB
admet-2088	423	8	in	in	ADP
admet-2088	423	9	efficient	efficient	ADJ
admet-2088	423	10	temperature	temperature	NOUN
admet-2088	423	11	increment	increment	NOUN
admet-2088	423	12	in	in	ADP
admet-2088	423	13	both	both	CCONJ
admet-2088	423	14	the	the	DET
admet-2088	423	15	c540	c540	PROPN
admet-2088	423	16	(	(	PUNCT
admet-2088	423	17	b16	b16	PROPN
admet-2088	423	18	/	/	SYM
admet-2088	423	19	f10	f10	PROPN
admet-2088	423	20	)	)	PUNCT
admet-2088	423	21	cell	cell	NOUN
admet-2088	423	22	line	line	NOUN
admet-2088	423	23	and	and	CCONJ
admet-2088	423	24	a	a	DET
admet-2088	423	25	melanoma	melanoma	NOUN
admet-2088	423	26	tumour	tumour	NOUN
admet-2088	423	27	model	model	NOUN
admet-2088	423	28	in	in	ADP
admet-2088	423	29	male	male	ADJ
admet-2088	423	30	balb	balb	ADJ
admet-2088	423	31	/	/	SYM
admet-2088	423	32	c	c	NOUN
admet-2088	423	33	mice	mouse	NOUN
admet-2088	423	34	.	.	PUNCT
admet-2088	424	1	histological	histological	ADJ
admet-2088	424	2	analysis	analysis	NOUN
admet-2088	424	3	and	and	CCONJ
admet-2088	424	4	tumour	tumour	NOUN
admet-2088	424	5	volume	volume	NOUN
admet-2088	424	6	decrease	decrease	NOUN
admet-2088	424	7	after	after	ADP
admet-2088	424	8	10	10	NUM
admet-2088	424	9	days	day	NOUN
admet-2088	424	10	showed	show	VERB
admet-2088	424	11	75	75	NUM
admet-2088	424	12	%	%	NOUN
admet-2088	424	13	necrosis	necrosis	NOUN
admet-2088	424	14	and	and	CCONJ
admet-2088	424	15	50	50	NUM
admet-2088	424	16	%	%	NOUN
admet-2088	424	17	decrement	decrement	ADJ
admet-2088	424	18	,	,	PUNCT
admet-2088	424	19	respectively	respectively	ADV
admet-2088	424	20	[	[	X
admet-2088	424	21	155	155	NUM
admet-2088	424	22	]	]	PUNCT
admet-2088	424	23	.	.	PUNCT
admet-2088	425	1	graphene	graphene	NOUN
admet-2088	425	2	-	-	PUNCT
admet-2088	425	3	based	base	VERB
admet-2088	425	4	nms	nms	NOUN
admet-2088	425	5	graphene	graphene	NOUN
admet-2088	425	6	-	-	PUNCT
admet-2088	425	7	based	base	VERB
admet-2088	425	8	nms	nms	NOUN
admet-2088	425	9	were	be	AUX
admet-2088	425	10	isolated	isolate	VERB
admet-2088	425	11	first	first	ADV
admet-2088	425	12	from	from	ADP
admet-2088	425	13	a	a	DET
admet-2088	425	14	bulk	bulk	ADJ
admet-2088	425	15	graphite	graphite	NOUN
admet-2088	425	16	.	.	PUNCT
admet-2088	426	1	these	these	DET
admet-2088	426	2	nms	nms	NOUN
admet-2088	426	3	are	be	AUX
admet-2088	426	4	classified	classify	VERB
admet-2088	426	5	into	into	ADP
admet-2088	426	6	various	various	ADJ
admet-2088	426	7	types	type	NOUN
admet-2088	426	8	,	,	PUNCT
admet-2088	426	9	including	include	VERB
admet-2088	426	10	graphene	graphene	NOUN
admet-2088	426	11	with	with	ADP
admet-2088	426	12	varied	varied	ADJ
admet-2088	426	13	layers	layer	NOUN
admet-2088	426	14	,	,	PUNCT
admet-2088	426	15	graphene	graphene	VERB
admet-2088	426	16	oxide	oxide	NOUN
admet-2088	426	17	(	(	PUNCT
admet-2088	426	18	go	go	VERB
admet-2088	426	19	)	)	PUNCT
admet-2088	426	20	and	and	CCONJ
admet-2088	426	21	reduced	reduce	VERB
admet-2088	426	22	go	go	NOUN
admet-2088	426	23	(	(	PUNCT
admet-2088	426	24	rgo	rgo	NOUN
admet-2088	426	25	)	)	PUNCT
admet-2088	427	1	[	[	X
admet-2088	427	2	156	156	NUM
admet-2088	427	3	]	]	PUNCT
admet-2088	427	4	.	.	PUNCT
admet-2088	428	1	however	however	ADV
admet-2088	428	2	,	,	PUNCT
admet-2088	428	3	go	go	VERB
admet-2088	428	4	and	and	CCONJ
admet-2088	428	5	rgo	rgo	PROPN
admet-2088	428	6	have	have	AUX
admet-2088	428	7	been	be	AUX
admet-2088	428	8	potentially	potentially	ADV
admet-2088	428	9	used	use	VERB
admet-2088	428	10	in	in	ADP
admet-2088	428	11	biomedical	biomedical	ADJ
admet-2088	428	12	and	and	CCONJ
admet-2088	428	13	pharmaceutical	pharmaceutical	NOUN
admet-2088	428	14	fields	field	NOUN
admet-2088	428	15	due	due	ADP
admet-2088	428	16	to	to	ADP
admet-2088	428	17	their	their	PRON
admet-2088	428	18	easy	easy	ADJ
admet-2088	428	19	availability	availability	NOUN
admet-2088	428	20	,	,	PUNCT
admet-2088	428	21	high	high	ADJ
admet-2088	428	22	biocompatibility	biocompatibility	NOUN
admet-2088	428	23	,	,	PUNCT
admet-2088	428	24	and	and	CCONJ
admet-2088	428	25	photothermal	photothermal	ADJ
admet-2088	428	26	and	and	CCONJ
admet-2088	428	27	tuneable	tuneable	ADJ
admet-2088	428	28	physicochemical	physicochemical	ADJ
admet-2088	428	29	properties	property	NOUN
admet-2088	428	30	[	[	X
admet-2088	428	31	157	157	NUM
admet-2088	428	32	]	]	PUNCT
admet-2088	428	33	.	.	PUNCT
admet-2088	429	1	as	as	ADV
admet-2088	429	2	far	far	ADV
admet-2088	429	3	as	as	SCONJ
admet-2088	429	4	cancer	cancer	NOUN
admet-2088	429	5	therapy	therapy	NOUN
admet-2088	429	6	is	be	AUX
admet-2088	429	7	concerned	concern	VERB
admet-2088	429	8	,	,	PUNCT
admet-2088	429	9	go	go	VERB
admet-2088	429	10	and	and	CCONJ
admet-2088	429	11	rgo	rgo	PROPN
admet-2088	429	12	are	be	AUX
admet-2088	429	13	being	be	AUX
admet-2088	429	14	used	use	VERB
admet-2088	429	15	either	either	CCONJ
admet-2088	429	16	as	as	ADP
admet-2088	429	17	drug	drug	NOUN
admet-2088	429	18	delivery	delivery	NOUN
admet-2088	429	19	vehicles	vehicle	NOUN
admet-2088	429	20	for	for	ADP
admet-2088	429	21	anticancer	anticancer	NOUN
admet-2088	429	22	drugs	drug	NOUN
admet-2088	429	23	or	or	CCONJ
admet-2088	429	24	as	as	ADP
admet-2088	429	25	photothermal	photothermal	ADJ
admet-2088	429	26	agents	agent	NOUN
admet-2088	430	1	[	[	X
admet-2088	430	2	158	158	NUM
admet-2088	430	3	]	]	PUNCT
admet-2088	430	4	.	.	PUNCT
admet-2088	431	1	graphene	graphene	ADJ
admet-2088	431	2	oxide	oxide	NOUN
admet-2088	431	3	graphene	graphene	NOUN
admet-2088	431	4	oxide	oxide	NOUN
admet-2088	431	5	(	(	PUNCT
admet-2088	431	6	go	go	VERB
admet-2088	431	7	)	)	PUNCT
admet-2088	431	8	is	be	AUX
admet-2088	431	9	synthesized	synthesize	VERB
admet-2088	431	10	from	from	ADP
admet-2088	431	11	graphite	graphite	NOUN
admet-2088	431	12	through	through	ADP
admet-2088	431	13	various	various	ADJ
admet-2088	431	14	methods	method	NOUN
admet-2088	431	15	,	,	PUNCT
admet-2088	431	16	such	such	ADJ
admet-2088	431	17	as	as	SCONJ
admet-2088	431	18	the	the	DET
admet-2088	431	19	hummers	hummer	NOUN
admet-2088	431	20	method	method	VERB
admet-2088	431	21	[	[	X
admet-2088	431	22	159	159	NUM
admet-2088	431	23	]	]	PUNCT
admet-2088	431	24	,	,	PUNCT
admet-2088	431	25	the	the	DET
admet-2088	431	26	brodie	brodie	PROPN
admet-2088	431	27	method	method	NOUN
admet-2088	432	1	[	[	X
admet-2088	432	2	160	160	NUM
admet-2088	432	3	]	]	PUNCT
admet-2088	432	4	,	,	PUNCT
admet-2088	432	5	and	and	CCONJ
admet-2088	432	6	the	the	DET
admet-2088	432	7	staudenmaier	staudenmaier	ADJ
admet-2088	432	8	method	method	NOUN
admet-2088	432	9	[	[	X
admet-2088	432	10	161	161	NUM
admet-2088	432	11	]	]	PUNCT
admet-2088	432	12	,	,	PUNCT
admet-2088	432	13	using	use	VERB
admet-2088	432	14	various	various	ADJ
admet-2088	432	15	chemical	chemical	ADJ
admet-2088	432	16	reagents	reagent	NOUN
admet-2088	432	17	[	[	X
admet-2088	432	18	157	157	NUM
admet-2088	432	19	]	]	PUNCT
admet-2088	432	20	.	.	PUNCT
admet-2088	433	1	the	the	DET
admet-2088	433	2	basic	basic	ADJ
admet-2088	433	3	principle	principle	NOUN
admet-2088	433	4	in	in	ADP
admet-2088	433	5	converting	convert	VERB
admet-2088	433	6	graphite	graphite	NOUN
admet-2088	433	7	to	to	PART
admet-2088	433	8	go	go	VERB
admet-2088	433	9	involves	involve	VERB
admet-2088	433	10	exfoliation	exfoliation	NOUN
admet-2088	433	11	and	and	CCONJ
admet-2088	433	12	oxidation	oxidation	NOUN
admet-2088	433	13	.	.	PUNCT
admet-2088	434	1	the	the	DET
admet-2088	434	2	puckered	pucker	VERB
admet-2088	434	3	sheets	sheet	NOUN
admet-2088	434	4	of	of	ADP
admet-2088	434	5	go	go	NOUN
admet-2088	434	6	are	be	AUX
admet-2088	434	7	exfoliated	exfoliate	VERB
admet-2088	434	8	and	and	CCONJ
admet-2088	434	9	then	then	ADV
admet-2088	434	10	oxidation	oxidation	NOUN
admet-2088	434	11	of	of	ADP
admet-2088	434	12	a	a	DET
admet-2088	434	13	basal	basal	ADJ
admet-2088	434	14	plane	plane	NOUN
admet-2088	434	15	resulted	result	VERB
admet-2088	434	16	in	in	ADP
admet-2088	434	17	the	the	DET
admet-2088	434	18	introduction	introduction	NOUN
admet-2088	434	19	of	of	ADP
admet-2088	434	20	different	different	ADJ
admet-2088	434	21	functional	functional	ADJ
admet-2088	434	22	groups	group	NOUN
admet-2088	434	23	such	such	ADJ
admet-2088	434	24	as	as	ADP
admet-2088	434	25	hydroxyl	hydroxyl	NOUN
admet-2088	434	26	,	,	PUNCT
admet-2088	434	27	epoxy	epoxy	NOUN
admet-2088	434	28	and	and	CCONJ
admet-2088	434	29	carboxyl	carboxyl	NOUN
admet-2088	435	1	[	[	X
admet-2088	435	2	162	162	NUM
admet-2088	435	3	]	]	PUNCT
admet-2088	435	4	.	.	PUNCT
admet-2088	436	1	these	these	DET
admet-2088	436	2	oxide	oxide	NOUN
admet-2088	436	3	groups	group	NOUN
admet-2088	436	4	confer	confer	VERB
admet-2088	436	5	go	go	VERB
admet-2088	436	6	the	the	DET
admet-2088	436	7	hydrophilicity	hydrophilicity	NOUN
admet-2088	436	8	and	and	CCONJ
admet-2088	436	9	the	the	DET
admet-2088	436	10	potential	potential	NOUN
admet-2088	436	11	to	to	PART
admet-2088	436	12	improve	improve	VERB
admet-2088	436	13	the	the	DET
admet-2088	436	14	solubility	solubility	NOUN
admet-2088	436	15	of	of	ADP
admet-2088	436	16	poorly	poorly	ADV
admet-2088	436	17	water	water	NOUN
admet-2088	436	18	-	-	PUNCT
admet-2088	436	19	soluble	soluble	ADJ
admet-2088	436	20	drugs	drug	NOUN
admet-2088	436	21	and	and	CCONJ
admet-2088	436	22	improve	improve	VERB
admet-2088	436	23	drug	drug	NOUN
admet-2088	436	24	absorption	absorption	NOUN
admet-2088	436	25	and	and	CCONJ
admet-2088	436	26	mechanical	mechanical	ADJ
admet-2088	436	27	strength	strength	NOUN
admet-2088	436	28	[	[	X
admet-2088	436	29	67,163	67,163	NUM
admet-2088	436	30	]	]	PUNCT
admet-2088	436	31	.	.	PUNCT
admet-2088	437	1	in	in	ADP
admet-2088	437	2	addition	addition	NOUN
admet-2088	437	3	,	,	PUNCT
admet-2088	437	4	go	go	VERB
admet-2088	437	5	can	can	AUX
admet-2088	437	6	be	be	AUX
admet-2088	437	7	functionalized	functionalize	VERB
admet-2088	437	8	through	through	ADP
admet-2088	437	9	covalent	covalent	ADJ
admet-2088	437	10	bonds	bond	NOUN
admet-2088	437	11	with	with	ADP
admet-2088	437	12	diverse	diverse	ADJ
admet-2088	437	13	classes	class	NOUN
admet-2088	437	14	of	of	ADP
admet-2088	437	15	drugs	drug	NOUN
admet-2088	437	16	under	under	ADP
admet-2088	437	17	mild	mild	ADJ
admet-2088	437	18	experimental	experimental	ADJ
admet-2088	437	19	conditions	condition	NOUN
admet-2088	437	20	.	.	PUNCT
admet-2088	438	1	initially	initially	ADV
admet-2088	438	2	,	,	PUNCT
admet-2088	438	3	rgo	rgo	PROPN
admet-2088	438	4	was	be	AUX
admet-2088	438	5	synthesized	synthesize	VERB
admet-2088	438	6	as	as	ADP
admet-2088	438	7	an	an	DET
admet-2088	438	8	alternative	alternative	ADJ
admet-2088	438	9	material	material	NOUN
admet-2088	438	10	to	to	PART
admet-2088	438	11	pristine	pristine	ADJ
admet-2088	438	12	graphite	graphite	NOUN
admet-2088	438	13	as	as	SCONJ
admet-2088	438	14	it	it	PRON
admet-2088	438	15	can	can	AUX
admet-2088	438	16	be	be	AUX
admet-2088	438	17	produced	produce	VERB
admet-2088	438	18	in	in	ADP
admet-2088	438	19	large	large	ADJ
admet-2088	438	20	amounts	amount	NOUN
admet-2088	439	1	[	[	X
admet-2088	439	2	164	164	NUM
admet-2088	439	3	]	]	PUNCT
admet-2088	439	4	.	.	PUNCT
admet-2088	440	1	basically	basically	ADV
admet-2088	440	2	,	,	PUNCT
admet-2088	440	3	rgo	rgo	PROPN
admet-2088	440	4	is	be	AUX
admet-2088	440	5	synthesized	synthesize	VERB
admet-2088	440	6	from	from	ADP
admet-2088	440	7	go	go	VERB
admet-2088	440	8	through	through	ADP
admet-2088	440	9	various	various	ADJ
admet-2088	440	10	methods	method	NOUN
admet-2088	440	11	such	such	ADJ
admet-2088	440	12	as	as	ADP
admet-2088	440	13	thermal	thermal	ADJ
admet-2088	440	14	,	,	PUNCT
admet-2088	440	15	chemical	chemical	NOUN
admet-2088	440	16	and	and	CCONJ
admet-2088	440	17	electrochemical	electrochemical	ADJ
admet-2088	440	18	reduction	reduction	NOUN
admet-2088	440	19	[	[	X
admet-2088	440	20	165	165	NUM
admet-2088	440	21	]	]	PUNCT
admet-2088	440	22	.	.	PUNCT
admet-2088	441	1	based	base	VERB
admet-2088	441	2	on	on	ADP
admet-2088	441	3	the	the	DET
admet-2088	441	4	synthesis	synthesis	NOUN
admet-2088	441	5	method	method	NOUN
admet-2088	441	6	,	,	PUNCT
admet-2088	441	7	the	the	DET
admet-2088	441	8	properties	property	NOUN
admet-2088	441	9	of	of	ADP
admet-2088	441	10	rgo	rgo	PROPN
admet-2088	441	11	varied	varied	ADJ
admet-2088	441	12	in	in	ADP
admet-2088	441	13	terms	term	NOUN
admet-2088	441	14	of	of	ADP
admet-2088	441	15	structure	structure	NOUN
admet-2088	441	16	,	,	PUNCT
admet-2088	441	17	thermal	thermal	ADJ
admet-2088	441	18	,	,	PUNCT
admet-2088	441	19	electrical	electrical	ADJ
admet-2088	441	20	and	and	CCONJ
admet-2088	441	21	mechanical	mechanical	ADJ
admet-2088	441	22	properties	property	NOUN
admet-2088	441	23	[	[	X
admet-2088	441	24	166	166	NUM
admet-2088	441	25	]	]	PUNCT
admet-2088	441	26	.	.	PUNCT
admet-2088	442	1	the	the	DET
admet-2088	442	2	oxygen	oxygen	NOUN
admet-2088	442	3	-	-	PUNCT
admet-2088	442	4	containing	contain	VERB
admet-2088	442	5	groups	group	NOUN
admet-2088	442	6	can	can	AUX
admet-2088	442	7	not	not	PART
admet-2088	442	8	be	be	AUX
admet-2088	442	9	removed	remove	VERB
admet-2088	442	10	completely	completely	ADV
admet-2088	442	11	and	and	CCONJ
admet-2088	442	12	residual	residual	ADJ
admet-2088	442	13	oxygen	oxygen	NOUN
admet-2088	442	14	groups	group	NOUN
admet-2088	442	15	provide	provide	VERB
admet-2088	442	16	rgo	rgo	PROPN
admet-2088	442	17	the	the	DET
admet-2088	442	18	opportunities	opportunity	NOUN
admet-2088	442	19	to	to	PART
admet-2088	442	20	be	be	AUX
admet-2088	442	21	modified	modify	VERB
admet-2088	442	22	with	with	ADP
admet-2088	442	23	different	different	ADJ
admet-2088	442	24	functional	functional	ADJ
admet-2088	442	25	or	or	CCONJ
admet-2088	442	26	conjugated	conjugate	VERB
admet-2088	442	27	with	with	ADP
admet-2088	442	28	different	different	ADJ
admet-2088	442	29	drugs	drug	NOUN
admet-2088	442	30	.	.	PUNCT
admet-2088	443	1	in	in	ADP
admet-2088	443	2	addition	addition	NOUN
admet-2088	443	3	,	,	PUNCT
admet-2088	443	4	there	there	PRON
admet-2088	443	5	is	be	VERB
admet-2088	443	6	a	a	DET
admet-2088	443	7	reduction	reduction	NOUN
admet-2088	443	8	in	in	ADP
admet-2088	443	9	graphene	graphene	NOUN
admet-2088	443	10	layer	layer	NOUN
admet-2088	443	11	distance	distance	NOUN
admet-2088	443	12	and	and	CCONJ
admet-2088	443	13	thickness	thickness	NOUN
admet-2088	443	14	because	because	SCONJ
admet-2088	443	15	of	of	ADP
admet-2088	443	16	the	the	DET
admet-2088	443	17	reduction	reduction	NOUN
admet-2088	443	18	in	in	ADP
admet-2088	443	19	branched	branched	ADJ
admet-2088	443	20	groups	group	NOUN
admet-2088	443	21	[	[	X
admet-2088	443	22	157	157	NUM
admet-2088	443	23	]	]	PUNCT
admet-2088	443	24	.	.	PUNCT
admet-2088	444	1	a	a	DET
admet-2088	444	2	novel	novel	ADJ
admet-2088	444	3	nanocomposite	nanocomposite	NOUN
admet-2088	444	4	hydrogel	hydrogel	NOUN
admet-2088	444	5	dds	dds	PROPN
admet-2088	444	6	was	be	AUX
admet-2088	444	7	developed	develop	VERB
admet-2088	444	8	to	to	PART
admet-2088	444	9	treat	treat	VERB
admet-2088	444	10	melanoma	melanoma	NOUN
admet-2088	444	11	and	and	CCONJ
admet-2088	444	12	associated	associated	ADJ
admet-2088	444	13	pathogenic	pathogenic	ADJ
admet-2088	444	14	infections	infection	NOUN
admet-2088	444	15	,	,	PUNCT
admet-2088	444	16	which	which	PRON
admet-2088	444	17	generally	generally	ADV
admet-2088	444	18	aggravate	aggravate	VERB
admet-2088	444	19	the	the	DET
admet-2088	444	20	melanoma	melanoma	ADJ
admet-2088	444	21	tissue	tissue	NOUN
admet-2088	444	22	.	.	PUNCT
admet-2088	445	1	herein	herein	NOUN
admet-2088	445	2	,	,	PUNCT
admet-2088	445	3	the	the	DET
admet-2088	445	4	anticancer	anticancer	NOUN
admet-2088	445	5	drug	drug	NOUN
admet-2088	445	6	fluorouracil	fluorouracil	NOUN
admet-2088	445	7	(	(	PUNCT
admet-2088	445	8	5fu	5fu	NOUN
admet-2088	445	9	)	)	PUNCT
admet-2088	445	10	was	be	AUX
admet-2088	445	11	loaded	load	VERB
admet-2088	445	12	onto	onto	ADP
admet-2088	445	13	rgo	rgo	PROPN
admet-2088	445	14	and	and	CCONJ
admet-2088	445	15	then	then	ADV
admet-2088	445	16	this	this	DET
admet-2088	445	17	nanodrug	nanodrug	NOUN
admet-2088	445	18	was	be	AUX
admet-2088	445	19	loaded	load	VERB
admet-2088	445	20	into	into	ADP
admet-2088	445	21	a	a	DET
admet-2088	445	22	polymeric	polymeric	ADJ
admet-2088	445	23	matrix	matrix	NOUN
admet-2088	445	24	of	of	ADP
admet-2088	445	25	functionalized	functionalized	ADJ
admet-2088	445	26	arabinoxylan	arabinoxylan	NOUN
admet-2088	445	27	(	(	PUNCT
admet-2088	445	28	carboxymethylarabinoxylan	carboxymethylarabinoxylan	NOUN
admet-2088	445	29	,	,	PUNCT
admet-2088	445	30	cmarx	cmarx	NOUN
admet-2088	445	31	)	)	PUNCT
admet-2088	445	32	extracted	extract	VERB
admet-2088	445	33	from	from	ADP
admet-2088	445	34	plantago	plantago	NOUN
admet-2088	445	35	ovata	ovata	NOUN
admet-2088	445	36	.	.	PUNCT
admet-2088	446	1	the	the	DET
admet-2088	446	2	cmarx	cmarx	NOUN
admet-2088	446	3	loaded	load	VERB
admet-2088	446	4	with	with	ADP
admet-2088	446	5	rgo-5fu	rgo-5fu	NOUN
admet-2088	446	6	was	be	AUX
admet-2088	446	7	then	then	ADV
admet-2088	446	8	cross	cross	ADJ
admet-2088	446	9	-	-	VERB
admet-2088	446	10	linked	link	VERB
admet-2088	446	11	with	with	ADP
admet-2088	446	12	tetraethylorthosilicate	tetraethylorthosilicate	NOUN
admet-2088	446	13	to	to	PART
admet-2088	446	14	form	form	VERB
admet-2088	446	15	nanocomposite	nanocomposite	PROPN
admet-2088	446	16	hydrogel	hydrogel	NOUN
admet-2088	446	17	(	(	PUNCT
admet-2088	446	18	hydrogel	hydrogel	NOUN
admet-2088	446	19	rgo5fu	rgo5fu	NOUN
admet-2088	446	20	-	-	PUNCT
admet-2088	446	21	cmarx	cmarx	NOUN
admet-2088	446	22	system	system	NOUN
admet-2088	446	23	)	)	PUNCT
admet-2088	446	24	.	.	PUNCT
admet-2088	447	1	these	these	DET
admet-2088	447	2	hydrogels	hydrogel	NOUN
admet-2088	447	3	showed	show	VERB
admet-2088	447	4	ph	ph	ADJ
admet-2088	447	5	sensitivity	sensitivity	NOUN
admet-2088	447	6	with	with	ADP
admet-2088	447	7	different	different	ADJ
admet-2088	447	8	swelling	swelling	NOUN
admet-2088	447	9	and	and	CCONJ
admet-2088	447	10	biodegradation	biodegradation	NOUN
admet-2088	447	11	under	under	ADP
admet-2088	447	12	different	different	ADJ
admet-2088	447	13	ph	ph	ADJ
admet-2088	447	14	conditions	condition	NOUN
admet-2088	447	15	,	,	PUNCT
admet-2088	447	16	resulting	result	VERB
admet-2088	447	17	in	in	ADP
admet-2088	447	18	sustained	sustained	ADJ
admet-2088	447	19	release	release	NOUN
admet-2088	447	20	of	of	ADP
admet-2088	447	21	loaded	load	VERB
admet-2088	447	22	5fu	5fu	NOUN
admet-2088	447	23	.	.	PUNCT
admet-2088	448	1	in	in	ADP
admet-2088	448	2	vitro	vitro	X
admet-2088	448	3	study	study	NOUN
admet-2088	448	4	revealed	reveal	VERB
admet-2088	448	5	that	that	SCONJ
admet-2088	448	6	this	this	DET
admet-2088	448	7	nanocomposite	nanocomposite	ADJ
admet-2088	448	8	hydrogel	hydrogel	NOUN
admet-2088	448	9	has	have	VERB
admet-2088	448	10	significant	significant	ADJ
admet-2088	448	11	anticancer	anticancer	NOUN
admet-2088	448	12	and	and	CCONJ
admet-2088	448	13	antibacterial	antibacterial	ADJ
admet-2088	448	14	activities	activity	NOUN
admet-2088	448	15	against	against	ADP
admet-2088	448	16	the	the	DET
admet-2088	448	17	u87	u87	ADJ
admet-2088	448	18	cell	cell	NOUN
admet-2088	448	19	line	line	NOUN
admet-2088	448	20	and	and	CCONJ
admet-2088	448	21	s.	s.	PROPN
admet-2088	448	22	aureus	aureus	PROPN
admet-2088	448	23	and	and	CCONJ
admet-2088	448	24	p.	p.	PROPN
admet-2088	448	25	aeruginosa	aeruginosa	PROPN
admet-2088	448	26	,	,	PUNCT
admet-2088	448	27	respectively	respectively	ADV
admet-2088	448	28	[	[	X
admet-2088	448	29	167	167	NUM
admet-2088	448	30	]	]	PUNCT
admet-2088	448	31	.	.	PUNCT
admet-2088	449	1	a	a	DET
admet-2088	449	2	novel	novel	ADJ
admet-2088	449	3	nanocomposite	nanocomposite	NOUN
admet-2088	449	4	sheet	sheet	NOUN
admet-2088	449	5	was	be	AUX
admet-2088	449	6	developed	develop	VERB
admet-2088	449	7	from	from	ADP
admet-2088	449	8	chitosan	chitosan	ADJ
admet-2088	449	9	oligosaccharide	oligosaccharide	NOUN
admet-2088	449	10	-	-	PUNCT
admet-2088	449	11	grafted	graft	VERB
admet-2088	449	12	nano	nano	NOUN
admet-2088	449	13	-	-	PUNCT
admet-2088	449	14	go	go	NOUN
admet-2088	449	15	(	(	PUNCT
admet-2088	449	16	ngo	ngo	PROPN
admet-2088	449	17	-	-	PUNCT
admet-2088	449	18	cos	cos	PROPN
admet-2088	449	19	)	)	PUNCT
admet-2088	449	20	,	,	PUNCT
admet-2088	449	21	modified	modify	VERB
admet-2088	449	22	with	with	ADP
admet-2088	449	23	cd47	cd47	PROPN
admet-2088	449	24	antibody	antibody	NOUN
admet-2088	449	25	and	and	CCONJ
admet-2088	449	26	loaded	load	VERB
admet-2088	449	27	with	with	ADP
admet-2088	449	28	dacarbazine	dacarbazine	NOUN
admet-2088	449	29	(	(	PUNCT
admet-2088	449	30	dcb	dcb	PROPN
admet-2088	449	31	)	)	PUNCT
admet-2088	449	32	(	(	PUNCT
admet-2088	449	33	ngo	ngo	PROPN
admet-2088	449	34	-	-	PUNCT
admet-2088	449	35	cos	cos	PROPN
admet-2088	449	36	-	-	PUNCT
admet-2088	449	37	cd47	cd47	PROPN
admet-2088	449	38	/	/	SYM
admet-2088	449	39	dcb	dcb	NOUN
admet-2088	449	40	)	)	PUNCT
admet-2088	449	41	for	for	ADP
admet-2088	449	42	synergistic	synergistic	ADJ
admet-2088	449	43	targeted	target	VERB
admet-2088	449	44	chemo	chemo	NOUN
admet-2088	449	45	-	-	PUNCT
admet-2088	449	46	photothermal	photothermal	ADJ
admet-2088	449	47	therapy	therapy	NOUN
admet-2088	449	48	against	against	ADP
admet-2088	449	49	melanoma	melanoma	NOUN
admet-2088	449	50	.	.	PUNCT
admet-2088	450	1	cos	cos	PROPN
admet-2088	450	2	enhanced	enhance	VERB
admet-2088	450	3	the	the	DET
admet-2088	450	4	biocompatibility	biocompatibility	NOUN
admet-2088	450	5	of	of	ADP
admet-2088	450	6	the	the	DET
admet-2088	450	7	nanocarriers	nanocarrier	NOUN
admet-2088	450	8	and	and	CCONJ
admet-2088	450	9	also	also	ADV
admet-2088	450	10	provided	provide	VERB
admet-2088	450	11	an	an	DET
admet-2088	450	12	active	active	ADJ
admet-2088	450	13	interface	interface	NOUN
admet-2088	450	14	for	for	ADP
admet-2088	450	15	modification	modification	NOUN
admet-2088	450	16	with	with	ADP
admet-2088	450	17	cd4	cd4	PROPN
admet-2088	450	18	antibody	antibody	NOUN
admet-2088	450	19	.	.	PUNCT
admet-2088	451	1	the	the	DET
admet-2088	451	2	anticancer	anticancer	NOUN
admet-2088	451	3	drug	drug	NOUN
admet-2088	451	4	dacarbazine	dacarbazine	NOUN
admet-2088	451	5	was	be	AUX
admet-2088	451	6	loaded	load	VERB
admet-2088	451	7	onto	onto	ADP
admet-2088	451	8	the	the	DET
admet-2088	451	9	nanocomposite	nanocomposite	NOUN
admet-2088	451	10	via	via	ADP
admet-2088	451	11	high	high	ADJ
admet-2088	451	12	capacity	capacity	NOUN
admet-2088	451	13	by	by	ADP
admet-2088	451	14	π	π	PROPN
admet-2088	451	15	–	–	PUNCT
admet-2088	451	16	π	π	NOUN
admet-2088	451	17	stacking	stacking	NOUN
admet-2088	451	18	.	.	PUNCT
admet-2088	452	1	the	the	DET
admet-2088	452	2	prepared	prepare	VERB
admet-2088	452	3	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	452	4	m.	m.	NOUN
admet-2088	452	5	kulkarni	kulkarni	PROPN
admet-2088	452	6	et	et	PROPN
admet-2088	452	7	al	al	PROPN
admet-2088	452	8	.	.	PROPN
admet-2088	452	9	admet	admet	PROPN
admet-2088	452	10	&	&	CCONJ
admet-2088	452	11	dmpk	dmpk	PROPN
admet-2088	452	12	12(1	12(1	PROPN
admet-2088	452	13	)	)	PUNCT
admet-2088	452	14	(	(	PUNCT
admet-2088	452	15	2024	2024	NUM
admet-2088	452	16	)	)	PUNCT
admet-2088	452	17	107	107	NUM
admet-2088	452	18	-	-	SYM
admet-2088	452	19	150	150	NUM
admet-2088	452	20	124	124	NUM
admet-2088	452	21	nanocomposite	nanocomposite	NOUN
admet-2088	452	22	drug	drug	NOUN
admet-2088	452	23	carrier	carrier	NOUN
admet-2088	452	24	showed	show	VERB
admet-2088	452	25	exceptional	exceptional	ADJ
admet-2088	452	26	biocompatibility	biocompatibility	NOUN
admet-2088	452	27	,	,	PUNCT
admet-2088	452	28	photothermal	photothermal	ADJ
admet-2088	452	29	conversion	conversion	NOUN
admet-2088	452	30	efficiency	efficiency	NOUN
admet-2088	452	31	,	,	PUNCT
admet-2088	452	32	precise	precise	ADJ
admet-2088	452	33	targeting	targeting	NOUN
admet-2088	452	34	,	,	PUNCT
admet-2088	452	35	and	and	CCONJ
admet-2088	452	36	fast	fast	ADJ
admet-2088	452	37	drug	drug	NOUN
admet-2088	452	38	release	release	NOUN
admet-2088	452	39	under	under	ADP
admet-2088	452	40	nir	nir	ADJ
admet-2088	452	41	irradiation	irradiation	NOUN
admet-2088	452	42	,	,	PUNCT
admet-2088	452	43	followed	follow	VERB
admet-2088	452	44	by	by	ADP
admet-2088	452	45	efficient	efficient	ADJ
admet-2088	452	46	apoptosis	apoptosis	NOUN
admet-2088	452	47	of	of	ADP
admet-2088	452	48	cancer	cancer	NOUN
admet-2088	452	49	cells	cell	NOUN
admet-2088	452	50	.	.	PUNCT
admet-2088	453	1	the	the	DET
admet-2088	453	2	cd47	cd47	PROPN
admet-2088	453	3	antibody	antibody	NOUN
admet-2088	453	4	enhanced	enhance	VERB
admet-2088	453	5	the	the	DET
admet-2088	453	6	targeting	targeting	NOUN
admet-2088	453	7	capability	capability	NOUN
admet-2088	453	8	of	of	ADP
admet-2088	453	9	the	the	DET
admet-2088	453	10	nanocomposite	nanocomposite	NOUN
admet-2088	453	11	against	against	ADP
admet-2088	453	12	melanoma	melanoma	NOUN
admet-2088	453	13	cells	cell	NOUN
admet-2088	453	14	.	.	PUNCT
admet-2088	454	1	the	the	DET
admet-2088	454	2	nanocomposite	nanocomposite	NOUN
admet-2088	454	3	was	be	AUX
admet-2088	454	4	able	able	ADJ
admet-2088	454	5	to	to	PART
admet-2088	454	6	release	release	VERB
admet-2088	454	7	the	the	DET
admet-2088	454	8	drug	drug	NOUN
admet-2088	454	9	efficiently	efficiently	ADV
admet-2088	454	10	,	,	PUNCT
admet-2088	454	11	induced	induce	VERB
admet-2088	454	12	by	by	ADP
admet-2088	454	13	both	both	PRON
admet-2088	454	14	exogenous	exogenous	ADJ
admet-2088	454	15	(	(	PUNCT
admet-2088	454	16	pdt	pdt	NOUN
admet-2088	454	17	)	)	PUNCT
admet-2088	454	18	and	and	CCONJ
admet-2088	454	19	endogenous	endogenous	ADJ
admet-2088	454	20	(	(	PUNCT
admet-2088	454	21	acidic	acidic	ADJ
admet-2088	454	22	environment	environment	NOUN
admet-2088	454	23	in	in	ADP
admet-2088	454	24	cancerous	cancerous	ADJ
admet-2088	454	25	tissue	tissue	NOUN
admet-2088	454	26	)	)	PUNCT
admet-2088	454	27	activation	activation	NOUN
admet-2088	454	28	to	to	PART
admet-2088	454	29	cause	cause	VERB
admet-2088	454	30	the	the	DET
admet-2088	454	31	death	death	NOUN
admet-2088	454	32	of	of	ADP
admet-2088	454	33	b16	b16	PROPN
admet-2088	454	34	-	-	PUNCT
admet-2088	454	35	f10	f10	NOUN
admet-2088	454	36	melanoma	melanoma	NOUN
admet-2088	454	37	cells	cell	NOUN
admet-2088	454	38	.	.	PUNCT
admet-2088	455	1	the	the	DET
admet-2088	455	2	ngocos	ngoco	NOUN
admet-2088	455	3	-	-	PUNCT
admet-2088	455	4	cd47	cd47	PROPN
admet-2088	455	5	/	/	SYM
admet-2088	455	6	dcb	dcb	NOUN
admet-2088	455	7	nanocarriers	nanocarrier	NOUN
admet-2088	455	8	(	(	PUNCT
admet-2088	455	9	chemotherapy	chemotherapy	NOUN
admet-2088	455	10	)	)	PUNCT
admet-2088	455	11	and	and	CCONJ
admet-2088	455	12	nir	nir	ADJ
admet-2088	455	13	irradiation	irradiation	NOUN
admet-2088	455	14	(	(	PUNCT
admet-2088	455	15	pdt	pdt	NOUN
admet-2088	455	16	)	)	PUNCT
admet-2088	455	17	simultaneously	simultaneously	ADV
admet-2088	455	18	induce	induce	VERB
admet-2088	455	19	apoptosis	apoptosis	NOUN
admet-2088	455	20	through	through	ADP
admet-2088	455	21	the	the	DET
admet-2088	455	22	mitochondria	mitochondria	NOUN
admet-2088	455	23	apoptosis	apoptosis	NOUN
admet-2088	455	24	pathway	pathway	NOUN
admet-2088	455	25	in	in	ADP
admet-2088	455	26	vitro	vitro	X
admet-2088	455	27	[	[	X
admet-2088	455	28	168	168	NUM
admet-2088	455	29	]	]	PUNCT
admet-2088	455	30	.	.	PUNCT
admet-2088	456	1	more	more	ADV
admet-2088	456	2	recently	recently	ADV
admet-2088	456	3	,	,	PUNCT
admet-2088	456	4	bamburowicz	bamburowicz	ADJ
admet-2088	456	5	-	-	PUNCT
admet-2088	456	6	klimkowska	klimkowska	NOUN
admet-2088	456	7	et	et	PROPN
admet-2088	456	8	al	al	PROPN
admet-2088	456	9	.	.	PUNCT
admet-2088	457	1	[	[	X
admet-2088	457	2	169	169	NUM
admet-2088	457	3	]	]	PUNCT
admet-2088	457	4	synthesized	synthesize	VERB
admet-2088	457	5	next	next	ADJ
admet-2088	457	6	-	-	PUNCT
admet-2088	457	7	generation	generation	NOUN
admet-2088	457	8	nms	nms	NOUN
admet-2088	457	9	graphene	graphene	NOUN
admet-2088	457	10	encapsulated	encapsulate	VERB
admet-2088	457	11	magnetic	magnetic	PROPN
admet-2088	457	12	nps	nps	PROPN
admet-2088	457	13	(	(	PUNCT
admet-2088	457	14	gemns	gemns	PROPN
admet-2088	457	15	)	)	PUNCT
admet-2088	457	16	for	for	ADP
admet-2088	457	17	the	the	DET
admet-2088	457	18	delivery	delivery	NOUN
admet-2088	457	19	of	of	ADP
admet-2088	457	20	genes	gene	NOUN
admet-2088	457	21	into	into	ADP
admet-2088	457	22	melanoma	melanoma	NOUN
admet-2088	457	23	cells	cell	NOUN
admet-2088	457	24	.	.	PUNCT
admet-2088	458	1	in	in	ADP
admet-2088	458	2	this	this	DET
admet-2088	458	3	study	study	NOUN
admet-2088	458	4	,	,	PUNCT
admet-2088	458	5	a	a	DET
admet-2088	458	6	green	green	ADJ
admet-2088	458	7	fluorescence	fluorescence	NOUN
admet-2088	458	8	protein	protein	NOUN
admet-2088	458	9	expression	expression	NOUN
admet-2088	458	10	plasmid	plasmid	ADJ
admet-2088	458	11	dna	dna	PROPN
admet-2088	458	12	(	(	PUNCT
admet-2088	458	13	pdna	pdna	PROPN
admet-2088	458	14	)	)	PUNCT
admet-2088	458	15	was	be	AUX
admet-2088	458	16	employed	employ	VERB
admet-2088	458	17	and	and	CCONJ
admet-2088	458	18	gemns	gemn	NOUN
admet-2088	458	19	were	be	AUX
admet-2088	458	20	decorated	decorate	VERB
admet-2088	458	21	with	with	ADP
admet-2088	458	22	branched	branched	ADJ
admet-2088	458	23	polyethyleneimine	polyethyleneimine	NOUN
admet-2088	458	24	(	(	PUNCT
admet-2088	458	25	pei	pei	PROPN
admet-2088	458	26	)	)	PUNCT
admet-2088	458	27	to	to	PART
admet-2088	458	28	synthesize	synthesize	VERB
admet-2088	458	29	nanotransporter	nanotransporter	NOUN
admet-2088	458	30	(	(	PUNCT
admet-2088	458	31	gemns	gemns	PROPN
admet-2088	458	32	-	-	PUNCT
admet-2088	458	33	pei	pei	PROPN
admet-2088	458	34	/	/	PUNCT
admet-2088	458	35	pdna	pdna	PROPN
admet-2088	458	36	.	.	PUNCT
admet-2088	459	1	the	the	DET
admet-2088	459	2	nanotransporter	nanotransporter	NOUN
admet-2088	459	3	was	be	AUX
admet-2088	459	4	capable	capable	ADJ
admet-2088	459	5	of	of	ADP
admet-2088	459	6	condensing	condense	VERB
admet-2088	459	7	p	p	NOUN
admet-2088	459	8	-	-	PUNCT
admet-2088	459	9	dna	dna	NOUN
admet-2088	459	10	,	,	PUNCT
admet-2088	459	11	leading	lead	VERB
admet-2088	459	12	to	to	ADP
admet-2088	459	13	their	their	PRON
admet-2088	459	14	efficient	efficient	ADJ
admet-2088	459	15	delivery	delivery	NOUN
admet-2088	459	16	into	into	ADP
admet-2088	459	17	the	the	DET
admet-2088	459	18	melanoma	melanoma	NOUN
admet-2088	459	19	cells	cell	NOUN
admet-2088	459	20	(	(	PUNCT
admet-2088	459	21	b16f10	b16f10	NOUN
admet-2088	459	22	)	)	PUNCT
admet-2088	459	23	.	.	PUNCT
admet-2088	460	1	nanodiamonds	nanodiamond	NOUN
admet-2088	460	2	nanodiamonds	nanodiamond	NOUN
admet-2088	460	3	are	be	AUX
admet-2088	460	4	carbon	carbon	NOUN
admet-2088	460	5	-	-	PUNCT
admet-2088	460	6	based	base	VERB
admet-2088	460	7	nms	nms	NOUN
admet-2088	460	8	with	with	ADP
admet-2088	460	9	biocompatibility	biocompatibility	NOUN
admet-2088	460	10	and	and	CCONJ
admet-2088	460	11	easily	easily	ADV
admet-2088	460	12	modified	modify	VERB
admet-2088	460	13	surfaces	surface	NOUN
admet-2088	460	14	.	.	PUNCT
admet-2088	461	1	thus	thus	ADV
admet-2088	461	2	,	,	PUNCT
admet-2088	461	3	nanodiamonds	nanodiamond	NOUN
admet-2088	461	4	are	be	AUX
admet-2088	461	5	considered	consider	VERB
admet-2088	461	6	a	a	DET
admet-2088	461	7	promising	promising	ADJ
admet-2088	461	8	candidate	candidate	NOUN
admet-2088	461	9	in	in	ADP
admet-2088	461	10	therapeutics	therapeutic	NOUN
admet-2088	461	11	.	.	PUNCT
admet-2088	462	1	gou	gou	PROPN
admet-2088	462	2	et	et	PROPN
admet-2088	462	3	al	al	PROPN
admet-2088	462	4	.	.	PUNCT
admet-2088	463	1	[	[	X
admet-2088	463	2	170	170	NUM
admet-2088	463	3	]	]	PUNCT
admet-2088	463	4	synthesized	synthesize	VERB
admet-2088	463	5	carboxylated	carboxylate	VERB
admet-2088	463	6	nanodiamonds	nanodiamond	NOUN
admet-2088	463	7	and	and	CCONJ
admet-2088	463	8	studied	study	VERB
admet-2088	463	9	tumour	tumour	NOUN
admet-2088	463	10	cell	cell	NOUN
admet-2088	463	11	migration	migration	NOUN
admet-2088	463	12	inhibition	inhibition	NOUN
admet-2088	463	13	.	.	PUNCT
admet-2088	464	1	the	the	DET
admet-2088	464	2	carboxylated	carboxylate	VERB
admet-2088	464	3	nanomedicine	nanomedicine	NOUN
admet-2088	464	4	enhanced	enhance	VERB
admet-2088	464	5	single	single	ADJ
admet-2088	464	6	-	-	PUNCT
admet-2088	464	7	cell	cell	NOUN
admet-2088	464	8	adhesion	adhesion	NOUN
admet-2088	464	9	and	and	CCONJ
admet-2088	464	10	impaired	impaired	ADJ
admet-2088	464	11	assembly	assembly	NOUN
admet-2088	464	12	of	of	ADP
admet-2088	464	13	the	the	DET
admet-2088	464	14	skeleton	skeleton	NOUN
admet-2088	464	15	.	.	PUNCT
admet-2088	465	1	these	these	DET
admet-2088	465	2	nms	nms	NOUN
admet-2088	465	3	showed	show	VERB
admet-2088	465	4	remarkable	remarkable	ADJ
admet-2088	465	5	inhibition	inhibition	NOUN
admet-2088	465	6	of	of	ADP
admet-2088	465	7	the	the	DET
admet-2088	465	8	migration	migration	NOUN
admet-2088	465	9	of	of	ADP
admet-2088	465	10	hela	hela	ADJ
admet-2088	465	11	cells	cell	NOUN
admet-2088	465	12	by	by	ADP
admet-2088	465	13	preventing	prevent	VERB
admet-2088	465	14	the	the	DET
admet-2088	465	15	epithelial	epithelial	NOUN
admet-2088	465	16	-	-	PUNCT
admet-2088	465	17	to	to	ADP
admet-2088	465	18	-	-	PUNCT
admet-2088	465	19	mesenchymal	mesenchymal	NOUN
admet-2088	465	20	transition	transition	NOUN
admet-2088	465	21	process	process	NOUN
admet-2088	465	22	via	via	ADP
admet-2088	465	23	the	the	DET
admet-2088	465	24	transforming	transform	VERB
admet-2088	465	25	growth	growth	NOUN
admet-2088	465	26	factor	factor	NOUN
admet-2088	465	27	β	β	X
admet-2088	465	28	signalling	signal	VERB
admet-2088	465	29	pathway	pathway	NOUN
admet-2088	465	30	(	(	PUNCT
admet-2088	465	31	tgf	tgf	PROPN
admet-2088	465	32	-	-	PUNCT
admet-2088	465	33	β	β	NOUN
admet-2088	465	34	)	)	PUNCT
admet-2088	465	35	.	.	PUNCT
admet-2088	466	1	in	in	ADP
admet-2088	466	2	addition	addition	NOUN
admet-2088	466	3	,	,	PUNCT
admet-2088	466	4	these	these	DET
admet-2088	466	5	nms	nms	NOUN
admet-2088	466	6	demonstrated	demonstrate	VERB
admet-2088	466	7	potential	potential	ADJ
admet-2088	466	8	reduction	reduction	NOUN
admet-2088	466	9	of	of	ADP
admet-2088	466	10	the	the	DET
admet-2088	466	11	metastasis	metastasis	NOUN
admet-2088	466	12	of	of	ADP
admet-2088	466	13	murine	murine	ADJ
admet-2088	466	14	b16	b16	NOUN
admet-2088	466	15	melanoma	melanoma	NOUN
admet-2088	466	16	cells	cell	NOUN
admet-2088	466	17	in	in	ADP
admet-2088	466	18	an	an	DET
admet-2088	466	19	in	in	ADP
admet-2088	466	20	vivo	vivo	ADJ
admet-2088	466	21	pulmonary	pulmonary	ADJ
admet-2088	466	22	metastasis	metastasis	NOUN
admet-2088	466	23	model	model	NOUN
admet-2088	466	24	.	.	PUNCT
admet-2088	467	1	organic	organic	ADJ
admet-2088	467	2	nms	nms	NOUN
admet-2088	467	3	organic	organic	ADJ
admet-2088	467	4	nms	nms	NOUN
admet-2088	467	5	are	be	AUX
admet-2088	467	6	the	the	DET
admet-2088	467	7	most	most	ADV
admet-2088	467	8	thoroughly	thoroughly	ADV
admet-2088	467	9	studied	study	VERB
admet-2088	467	10	and	and	CCONJ
admet-2088	467	11	applied	apply	VERB
admet-2088	467	12	as	as	ADP
admet-2088	467	13	one	one	NUM
admet-2088	467	14	of	of	ADP
admet-2088	467	15	the	the	DET
admet-2088	467	16	most	most	ADV
admet-2088	467	17	attractive	attractive	ADJ
admet-2088	467	18	drug	drug	NOUN
admet-2088	467	19	delivery	delivery	NOUN
admet-2088	467	20	vehicles	vehicle	NOUN
admet-2088	467	21	due	due	ADP
admet-2088	467	22	to	to	ADP
admet-2088	467	23	their	their	PRON
admet-2088	467	24	innate	innate	ADJ
admet-2088	467	25	and	and	CCONJ
admet-2088	467	26	significant	significant	ADJ
admet-2088	467	27	characteristics	characteristic	NOUN
admet-2088	467	28	such	such	ADJ
admet-2088	467	29	as	as	ADP
admet-2088	467	30	biocompatibility	biocompatibility	NOUN
admet-2088	467	31	,	,	PUNCT
admet-2088	467	32	biodegradability	biodegradability	NOUN
admet-2088	467	33	and	and	CCONJ
admet-2088	467	34	ease	ease	VERB
admet-2088	467	35	path	path	NOUN
admet-2088	467	36	of	of	ADP
admet-2088	467	37	drug	drug	NOUN
admet-2088	467	38	molecule	molecule	NOUN
admet-2088	467	39	encapsulation	encapsulation	NOUN
admet-2088	467	40	[	[	X
admet-2088	467	41	171	171	NUM
admet-2088	467	42	]	]	PUNCT
admet-2088	467	43	.	.	PUNCT
admet-2088	468	1	organic	organic	ADJ
admet-2088	468	2	nms	nms	NOUN
admet-2088	468	3	are	be	AUX
admet-2088	468	4	generally	generally	ADV
admet-2088	468	5	comprised	comprise	VERB
admet-2088	468	6	of	of	ADP
admet-2088	468	7	polymers	polymer	NOUN
admet-2088	468	8	and	and	CCONJ
admet-2088	468	9	lipids	lipid	NOUN
admet-2088	468	10	,	,	PUNCT
admet-2088	468	11	which	which	PRON
admet-2088	468	12	can	can	AUX
admet-2088	468	13	be	be	AUX
admet-2088	468	14	designed	design	VERB
admet-2088	468	15	into	into	ADP
admet-2088	468	16	different	different	ADJ
admet-2088	468	17	suitable	suitable	ADJ
admet-2088	468	18	structures	structure	NOUN
admet-2088	468	19	to	to	PART
admet-2088	468	20	increase	increase	VERB
admet-2088	468	21	payload	payload	ADJ
admet-2088	468	22	capacity	capacity	NOUN
admet-2088	468	23	and	and	CCONJ
admet-2088	468	24	controlled	control	VERB
admet-2088	468	25	release	release	NOUN
admet-2088	468	26	of	of	ADP
admet-2088	468	27	the	the	DET
admet-2088	468	28	payload	payload	NOUN
admet-2088	468	29	at	at	ADP
admet-2088	468	30	the	the	DET
admet-2088	468	31	targeted	target	VERB
admet-2088	468	32	site	site	NOUN
admet-2088	468	33	,	,	PUNCT
admet-2088	468	34	leading	lead	VERB
admet-2088	468	35	to	to	ADP
admet-2088	468	36	the	the	DET
admet-2088	468	37	significant	significant	ADJ
admet-2088	468	38	enhancement	enhancement	NOUN
admet-2088	468	39	of	of	ADP
admet-2088	468	40	the	the	DET
admet-2088	468	41	therapeutic	therapeutic	ADJ
admet-2088	468	42	efficiency	efficiency	NOUN
admet-2088	468	43	of	of	ADP
admet-2088	468	44	the	the	DET
admet-2088	468	45	loaded	load	VERB
admet-2088	468	46	drug	drug	NOUN
admet-2088	468	47	with	with	ADP
admet-2088	468	48	minimized	minimized	ADJ
admet-2088	468	49	side	side	NOUN
admet-2088	468	50	effects	effect	NOUN
admet-2088	468	51	.	.	PUNCT
admet-2088	469	1	in	in	ADP
admet-2088	469	2	addition	addition	NOUN
admet-2088	469	3	,	,	PUNCT
admet-2088	469	4	many	many	ADJ
admet-2088	469	5	organic	organic	ADJ
admet-2088	469	6	nms	nms	NOUN
admet-2088	469	7	exhibit	exhibit	NOUN
admet-2088	469	8	stimuli	stimuli	VERB
admet-2088	469	9	-	-	PUNCT
admet-2088	469	10	responsive	responsive	ADJ
admet-2088	469	11	properties	property	NOUN
admet-2088	469	12	that	that	PRON
admet-2088	469	13	give	give	VERB
admet-2088	469	14	impetus	impetus	NOUN
admet-2088	469	15	to	to	ADP
admet-2088	469	16	the	the	DET
admet-2088	469	17	site	site	NOUN
admet-2088	469	18	-	-	PUNCT
admet-2088	469	19	specific	specific	ADJ
admet-2088	469	20	drug	drug	NOUN
admet-2088	469	21	delivery	delivery	NOUN
admet-2088	469	22	more	more	ADV
admet-2088	469	23	precisely	precisely	ADV
admet-2088	469	24	to	to	ADP
admet-2088	469	25	the	the	DET
admet-2088	469	26	cancerous	cancerous	ADJ
admet-2088	469	27	tissues	tissue	NOUN
admet-2088	470	1	[	[	X
admet-2088	470	2	172,173	172,173	NUM
admet-2088	470	3	]	]	PUNCT
admet-2088	470	4	.	.	PUNCT
admet-2088	471	1	by	by	ADP
admet-2088	471	2	linking	link	VERB
admet-2088	471	3	desired	desire	VERB
admet-2088	471	4	functional	functional	ADJ
admet-2088	471	5	groups	group	NOUN
admet-2088	471	6	,	,	PUNCT
admet-2088	471	7	organic	organic	ADJ
admet-2088	471	8	nms	nms	NOUN
admet-2088	471	9	can	can	AUX
admet-2088	471	10	be	be	AUX
admet-2088	471	11	employed	employ	VERB
admet-2088	471	12	for	for	ADP
admet-2088	471	13	active	active	ADJ
admet-2088	471	14	or	or	CCONJ
admet-2088	471	15	targeted	target	VERB
admet-2088	471	16	drug	drug	NOUN
admet-2088	471	17	delivery	delivery	NOUN
admet-2088	471	18	capabilities	capability	NOUN
admet-2088	471	19	.	.	PUNCT
admet-2088	472	1	organic	organic	ADJ
admet-2088	472	2	nms	nms	NOUN
admet-2088	472	3	include	include	VERB
admet-2088	472	4	polymeric	polymeric	NOUN
admet-2088	472	5	,	,	PUNCT
admet-2088	472	6	micelles	micelle	NOUN
admet-2088	472	7	,	,	PUNCT
admet-2088	472	8	dendrimers	dendrimer	NOUN
admet-2088	472	9	,	,	PUNCT
admet-2088	472	10	nanogel	nanogel	NOUN
admet-2088	472	11	,	,	PUNCT
admet-2088	472	12	nanocrystals	nanocrystal	NOUN
admet-2088	472	13	,	,	PUNCT
admet-2088	472	14	nanoemulsion	nanoemulsion	NOUN
admet-2088	472	15	,	,	PUNCT
admet-2088	472	16	liposomes	liposome	NOUN
admet-2088	472	17	,	,	PUNCT
admet-2088	472	18	niosomes	niosome	NOUN
admet-2088	472	19	,	,	PUNCT
admet-2088	472	20	sln	sln	NOUN
admet-2088	472	21	and	and	CCONJ
admet-2088	472	22	exosomes	exosome	NOUN
admet-2088	472	23	(	(	PUNCT
admet-2088	472	24	figure	figure	NOUN
admet-2088	472	25	4	4	NUM
admet-2088	472	26	)	)	PUNCT
admet-2088	472	27	.	.	PUNCT
admet-2088	473	1	figure	figure	VERB
admet-2088	473	2	4	4	NUM
admet-2088	473	3	.	.	PUNCT
admet-2088	473	4	illustration	illustration	NOUN
admet-2088	473	5	of	of	ADP
admet-2088	473	6	different	different	ADJ
admet-2088	473	7	types	type	NOUN
admet-2088	473	8	of	of	ADP
admet-2088	473	9	organic	organic	ADJ
admet-2088	473	10	nms	nms	NOUN
admet-2088	473	11	:	:	PUNCT
admet-2088	473	12	polymeric	polymeric	ADJ
admet-2088	473	13	nms	nms	NOUN
admet-2088	473	14	and	and	CCONJ
admet-2088	473	15	lipid	lipid	NOUN
admet-2088	473	16	-	-	PUNCT
admet-2088	473	17	based	base	VERB
admet-2088	473	18	nms	nms	PROPN
admet-2088	473	19	admet	admet	PROPN
admet-2088	473	20	&	&	CCONJ
admet-2088	473	21	dmpk	dmpk	PROPN
admet-2088	473	22	12(1	12(1	PROPN
admet-2088	473	23	)	)	PUNCT
admet-2088	473	24	(	(	PUNCT
admet-2088	473	25	2024	2024	NUM
admet-2088	473	26	)	)	PUNCT
admet-2088	473	27	107	107	NUM
admet-2088	473	28	-	-	SYM
admet-2088	473	29	150	150	NUM
admet-2088	473	30	nanomaterial	nanomaterial	NOUN
admet-2088	473	31	-	-	PUNCT
admet-2088	473	32	based	base	VERB
admet-2088	473	33	drug	drug	NOUN
admet-2088	473	34	delivery	delivery	NOUN
admet-2088	473	35	systems	system	NOUN
admet-2088	473	36	for	for	ADP
admet-2088	473	37	melanoma	melanoma	NOUN
admet-2088	473	38	therapy	therapy	NOUN
admet-2088	473	39	doi	doi	NOUN
admet-2088	473	40	:	:	PUNCT
admet-2088	473	41	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	PRON
admet-2088	473	42	125	125	NUM
admet-2088	473	43	polymeric	polymeric	ADJ
admet-2088	473	44	nms	nms	NOUN
admet-2088	473	45	polymeric	polymeric	PROPN
admet-2088	473	46	nps	nps	PROPN
admet-2088	473	47	are	be	AUX
admet-2088	473	48	considered	consider	VERB
admet-2088	473	49	a	a	DET
admet-2088	473	50	versatile	versatile	ADJ
admet-2088	473	51	category	category	NOUN
admet-2088	473	52	of	of	ADP
admet-2088	473	53	nanocarriers	nanocarrier	NOUN
admet-2088	473	54	that	that	PRON
admet-2088	473	55	are	be	AUX
admet-2088	473	56	widely	widely	ADV
admet-2088	473	57	employed	employ	VERB
admet-2088	473	58	in	in	ADP
admet-2088	473	59	controlled	control	VERB
admet-2088	473	60	and	and	CCONJ
admet-2088	473	61	site	site	NOUN
admet-2088	473	62	-	-	PUNCT
admet-2088	473	63	specific	specific	ADJ
admet-2088	473	64	drug	drug	NOUN
admet-2088	473	65	delivery	delivery	NOUN
admet-2088	474	1	[	[	X
admet-2088	474	2	174	174	NUM
admet-2088	474	3	]	]	PUNCT
admet-2088	474	4	.	.	PUNCT
admet-2088	475	1	these	these	PRON
admet-2088	475	2	are	be	AUX
admet-2088	475	3	classified	classify	VERB
admet-2088	475	4	into	into	ADP
admet-2088	475	5	three	three	NUM
admet-2088	475	6	generations	generation	NOUN
admet-2088	475	7	:	:	PUNCT
admet-2088	475	8	(	(	PUNCT
admet-2088	475	9	i	i	NOUN
admet-2088	475	10	)	)	PUNCT
admet-2088	475	11	the	the	DET
admet-2088	475	12	first	first	ADJ
admet-2088	475	13	generation	generation	NOUN
admet-2088	475	14	of	of	ADP
admet-2088	475	15	polymeric	polymeric	ADJ
admet-2088	475	16	nps	nps	PROPN
admet-2088	475	17	has	have	AUX
admet-2088	475	18	been	be	AUX
admet-2088	475	19	used	use	VERB
admet-2088	475	20	to	to	PART
admet-2088	475	21	encapsulate	encapsulate	VERB
admet-2088	475	22	the	the	DET
admet-2088	475	23	active	active	ADJ
admet-2088	475	24	ingredients	ingredient	NOUN
admet-2088	475	25	and	and	CCONJ
admet-2088	475	26	provide	provide	VERB
admet-2088	475	27	their	their	PRON
admet-2088	475	28	sustained	sustained	ADJ
admet-2088	475	29	release	release	NOUN
admet-2088	475	30	,	,	PUNCT
admet-2088	475	31	(	(	PUNCT
admet-2088	475	32	ii	ii	NOUN
admet-2088	475	33	)	)	PUNCT
admet-2088	475	34	the	the	DET
admet-2088	475	35	second	second	ADJ
admet-2088	475	36	generation	generation	NOUN
admet-2088	475	37	of	of	ADP
admet-2088	475	38	polymeric	polymeric	ADJ
admet-2088	475	39	nps	nps	PROPN
admet-2088	475	40	focussed	focusse	VERB
admet-2088	475	41	on	on	ADP
admet-2088	475	42	the	the	DET
admet-2088	475	43	strategies	strategy	NOUN
admet-2088	475	44	to	to	PART
admet-2088	475	45	deliver	deliver	VERB
admet-2088	475	46	the	the	DET
admet-2088	475	47	drugs	drug	NOUN
admet-2088	475	48	in	in	ADP
admet-2088	475	49	the	the	DET
admet-2088	475	50	target	target	NOUN
admet-2088	475	51	sites	site	NOUN
admet-2088	475	52	by	by	ADP
admet-2088	475	53	incorporating	incorporate	VERB
admet-2088	475	54	stimuli	stimulus	NOUN
admet-2088	475	55	-	-	PUNCT
admet-2088	475	56	responsive	responsive	ADJ
admet-2088	475	57	properties	property	NOUN
admet-2088	475	58	,	,	PUNCT
admet-2088	475	59	and	and	CCONJ
admet-2088	475	60	(	(	PUNCT
admet-2088	475	61	iii	iii	NOUN
admet-2088	475	62	)	)	PUNCT
admet-2088	475	63	polymeric	polymeric	NOUN
admet-2088	475	64	nps	nps	PROPN
admet-2088	475	65	of	of	ADP
admet-2088	475	66	third	third	ADJ
admet-2088	475	67	generation	generation	NOUN
admet-2088	475	68	represented	represent	VERB
admet-2088	475	69	by	by	ADP
admet-2088	475	70	multifunctionalities	multifunctionalitie	NOUN
admet-2088	475	71	including	include	VERB
admet-2088	475	72	targeting	target	VERB
admet-2088	475	73	along	along	ADP
admet-2088	475	74	with	with	ADP
admet-2088	475	75	multi	multi	ADJ
admet-2088	475	76	-	-	ADJ
admet-2088	475	77	drug	drug	ADJ
admet-2088	475	78	release	release	NOUN
admet-2088	475	79	properties	property	NOUN
admet-2088	475	80	[	[	X
admet-2088	475	81	175	175	NUM
admet-2088	475	82	]	]	PUNCT
admet-2088	475	83	.	.	PUNCT
admet-2088	476	1	various	various	ADJ
admet-2088	476	2	physicochemical	physicochemical	ADJ
admet-2088	476	3	properties	property	NOUN
admet-2088	476	4	of	of	ADP
admet-2088	476	5	polymers	polymer	NOUN
admet-2088	476	6	,	,	PUNCT
admet-2088	476	7	including	include	VERB
admet-2088	476	8	size	size	NOUN
admet-2088	476	9	,	,	PUNCT
admet-2088	476	10	shape	shape	NOUN
admet-2088	476	11	,	,	PUNCT
admet-2088	476	12	surface	surface	NOUN
admet-2088	476	13	charges	charge	NOUN
admet-2088	476	14	,	,	PUNCT
admet-2088	476	15	flexibility	flexibility	NOUN
admet-2088	476	16	,	,	PUNCT
admet-2088	476	17	and	and	CCONJ
admet-2088	476	18	length	length	NOUN
admet-2088	476	19	of	of	ADP
admet-2088	476	20	the	the	DET
admet-2088	476	21	carbon	carbon	NOUN
admet-2088	476	22	chain	chain	NOUN
admet-2088	476	23	,	,	PUNCT
admet-2088	476	24	have	have	AUX
admet-2088	476	25	been	be	AUX
admet-2088	476	26	readily	readily	ADV
admet-2088	476	27	explored	explore	VERB
admet-2088	476	28	for	for	ADP
admet-2088	476	29	the	the	DET
admet-2088	476	30	enhancement	enhancement	NOUN
admet-2088	476	31	of	of	ADP
admet-2088	476	32	characteristics	characteristic	NOUN
admet-2088	476	33	of	of	ADP
admet-2088	476	34	polymers	polymer	NOUN
admet-2088	476	35	such	such	ADJ
admet-2088	476	36	as	as	ADP
admet-2088	476	37	high	high	ADJ
admet-2088	476	38	drug	drug	NOUN
admet-2088	476	39	loading	loading	NOUN
admet-2088	476	40	,	,	PUNCT
admet-2088	476	41	biodegradability	biodegradability	NOUN
admet-2088	476	42	,	,	PUNCT
admet-2088	476	43	biocompatibility	biocompatibility	NOUN
admet-2088	476	44	,	,	PUNCT
admet-2088	476	45	reduction	reduction	NOUN
admet-2088	476	46	in	in	ADP
admet-2088	476	47	immunological	immunological	ADJ
admet-2088	476	48	reaction	reaction	NOUN
admet-2088	476	49	,	,	PUNCT
admet-2088	476	50	ease	ease	NOUN
admet-2088	476	51	of	of	ADP
admet-2088	476	52	surface	surface	NOUN
admet-2088	476	53	modification	modification	NOUN
admet-2088	476	54	[	[	X
admet-2088	476	55	176	176	NUM
admet-2088	476	56	]	]	PUNCT
admet-2088	476	57	,	,	PUNCT
admet-2088	476	58	functionalization	functionalization	NOUN
admet-2088	476	59	with	with	ADP
admet-2088	476	60	ligands	ligand	NOUN
admet-2088	476	61	for	for	ADP
admet-2088	476	62	the	the	DET
admet-2088	476	63	improvement	improvement	NOUN
admet-2088	476	64	of	of	ADP
admet-2088	476	65	binding	bind	VERB
admet-2088	476	66	affinity	affinity	NOUN
admet-2088	476	67	to	to	ADP
admet-2088	476	68	specific	specific	ADJ
admet-2088	476	69	receptor	receptor	NOUN
admet-2088	476	70	or	or	CCONJ
admet-2088	476	71	cancerous	cancerous	ADJ
admet-2088	476	72	cells	cell	NOUN
admet-2088	476	73	[	[	X
admet-2088	476	74	177	177	NUM
admet-2088	476	75	]	]	PUNCT
admet-2088	476	76	.	.	PUNCT
admet-2088	477	1	based	base	VERB
admet-2088	477	2	on	on	ADP
admet-2088	477	3	the	the	DET
admet-2088	477	4	source	source	NOUN
admet-2088	477	5	of	of	ADP
admet-2088	477	6	origin	origin	NOUN
admet-2088	477	7	,	,	PUNCT
admet-2088	477	8	polymers	polymer	NOUN
admet-2088	477	9	are	be	AUX
admet-2088	477	10	of	of	ADP
admet-2088	477	11	two	two	NUM
admet-2088	477	12	types	type	NOUN
admet-2088	477	13	:	:	PUNCT
admet-2088	477	14	synthetic	synthetic	ADJ
admet-2088	477	15	polymers	polymer	NOUN
admet-2088	477	16	(	(	PUNCT
admet-2088	477	17	e.g.	e.g.	ADV
admet-2088	477	18	,	,	PUNCT
admet-2088	477	19	poly(lactic	poly(lactic	ADJ
admet-2088	477	20	acid	acid	NOUN
admet-2088	477	21	)	)	PUNCT
admet-2088	477	22	(	(	PUNCT
admet-2088	477	23	pla	pla	NOUN
admet-2088	477	24	)	)	PUNCT
admet-2088	477	25	,	,	PUNCT
admet-2088	477	26	poly	poly	ADJ
admet-2088	477	27	(	(	PUNCT
admet-2088	477	28	glycolic	glycolic	NOUN
admet-2088	477	29	acid	acid	NOUN
admet-2088	477	30	)	)	PUNCT
admet-2088	477	31	(	(	PUNCT
admet-2088	477	32	pga	pga	PROPN
admet-2088	477	33	)	)	PUNCT
admet-2088	477	34	,	,	PUNCT
admet-2088	477	35	poly(lactic	poly(lactic	PROPN
admet-2088	477	36	-	-	PUNCT
admet-2088	477	37	co	co	NOUN
admet-2088	477	38	-	-	ADJ
admet-2088	477	39	glycolic	glycolic	ADJ
admet-2088	477	40	acid	acid	NOUN
admet-2088	477	41	)	)	PUNCT
admet-2088	477	42	(	(	PUNCT
admet-2088	477	43	plga	plga	NOUN
admet-2088	477	44	)	)	PUNCT
admet-2088	477	45	,	,	PUNCT
admet-2088	477	46	poly(-caprolactone	poly(-caprolactone	NOUN
admet-2088	477	47	)	)	PUNCT
admet-2088	477	48	(	(	PUNCT
admet-2088	477	49	pcl	pcl	PROPN
admet-2088	477	50	)	)	PUNCT
admet-2088	477	51	etc	etc	X
admet-2088	477	52	.	.	X
admet-2088	477	53	)	)	PUNCT
admet-2088	477	54	and	and	CCONJ
admet-2088	477	55	natural	natural	ADJ
admet-2088	477	56	polymers	polymer	NOUN
admet-2088	477	57	,	,	PUNCT
admet-2088	477	58	including	include	VERB
admet-2088	477	59	alginate	alginate	NOUN
admet-2088	477	60	,	,	PUNCT
admet-2088	477	61	chitosan	chitosan	NOUN
admet-2088	477	62	,	,	PUNCT
admet-2088	477	63	gelatin	gelatin	NOUN
admet-2088	477	64	,	,	PUNCT
admet-2088	477	65	collagen	collagen	NOUN
admet-2088	477	66	,	,	PUNCT
admet-2088	477	67	dextran	dextran	NOUN
admet-2088	477	68	,	,	PUNCT
admet-2088	477	69	heparin	heparin	ADJ
admet-2088	477	70	and	and	CCONJ
admet-2088	477	71	albumin	albumin	NOUN
admet-2088	477	72	[	[	X
admet-2088	477	73	178	178	NUM
admet-2088	477	74	]	]	PUNCT
admet-2088	477	75	.	.	PUNCT
admet-2088	478	1	depending	depend	VERB
admet-2088	478	2	on	on	ADP
admet-2088	478	3	the	the	DET
admet-2088	478	4	methods	method	NOUN
admet-2088	478	5	of	of	ADP
admet-2088	478	6	preparation	preparation	NOUN
admet-2088	478	7	,	,	PUNCT
admet-2088	478	8	polymeric	polymeric	ADJ
admet-2088	478	9	nps	nps	PROPN
admet-2088	478	10	are	be	AUX
admet-2088	478	11	either	either	CCONJ
admet-2088	478	12	nanocapsules	nanocapsule	NOUN
admet-2088	478	13	or	or	CCONJ
admet-2088	478	14	nanospheres	nanosphere	NOUN
admet-2088	478	15	.	.	PUNCT
admet-2088	479	1	nanocapsules	nanocapsule	NOUN
admet-2088	479	2	have	have	VERB
admet-2088	479	3	core	core	NOUN
admet-2088	479	4	-	-	PUNCT
admet-2088	479	5	shell	shell	NOUN
admet-2088	479	6	structures	structure	NOUN
admet-2088	479	7	with	with	ADP
admet-2088	479	8	the	the	DET
admet-2088	479	9	drug	drug	NOUN
admet-2088	479	10	encapsulated	encapsulate	VERB
admet-2088	479	11	inside	inside	ADP
admet-2088	479	12	a	a	DET
admet-2088	479	13	polymeric	polymeric	ADJ
admet-2088	479	14	shell	shell	NOUN
admet-2088	479	15	coat	coat	NOUN
admet-2088	479	16	or	or	CCONJ
admet-2088	479	17	membrane	membrane	NOUN
admet-2088	479	18	,	,	PUNCT
admet-2088	479	19	while	while	SCONJ
admet-2088	479	20	nanospheres	nanosphere	NOUN
admet-2088	479	21	are	be	AUX
admet-2088	479	22	matrix	matrix	NOUN
admet-2088	479	23	-	-	PUNCT
admet-2088	479	24	type	type	NOUN
admet-2088	479	25	structures	structure	NOUN
admet-2088	479	26	where	where	SCONJ
admet-2088	479	27	the	the	DET
admet-2088	479	28	drug	drug	NOUN
admet-2088	479	29	is	be	AUX
admet-2088	479	30	dispersed	disperse	VERB
admet-2088	479	31	throughout	throughout	ADP
admet-2088	479	32	the	the	DET
admet-2088	479	33	polymeric	polymeric	ADJ
admet-2088	479	34	matrix	matrix	NOUN
admet-2088	479	35	[	[	X
admet-2088	479	36	179	179	NUM
admet-2088	479	37	]	]	PUNCT
admet-2088	479	38	.	.	PUNCT
admet-2088	480	1	they	they	PRON
admet-2088	480	2	can	can	AUX
admet-2088	480	3	also	also	ADV
admet-2088	480	4	be	be	AUX
admet-2088	480	5	classified	classify	VERB
admet-2088	480	6	into	into	ADP
admet-2088	480	7	two	two	NUM
admet-2088	480	8	general	general	ADJ
admet-2088	480	9	categories	category	NOUN
admet-2088	480	10	,	,	PUNCT
admet-2088	480	11	such	such	ADJ
admet-2088	480	12	as	as	ADP
admet-2088	480	13	homopolymers	homopolymer	NOUN
admet-2088	480	14	(	(	PUNCT
admet-2088	480	15	formed	form	VERB
admet-2088	480	16	with	with	ADP
admet-2088	480	17	the	the	DET
admet-2088	480	18	same	same	ADJ
admet-2088	480	19	monomers	monomer	NOUN
admet-2088	480	20	)	)	PUNCT
admet-2088	480	21	and	and	CCONJ
admet-2088	480	22	copolymers	copolymer	NOUN
admet-2088	480	23	(	(	PUNCT
admet-2088	480	24	developed	develop	VERB
admet-2088	480	25	from	from	ADP
admet-2088	480	26	different	different	ADJ
admet-2088	480	27	monomers	monomer	NOUN
admet-2088	480	28	)	)	PUNCT
admet-2088	480	29	.	.	PUNCT
admet-2088	481	1	in	in	ADP
admet-2088	481	2	this	this	DET
admet-2088	481	3	part	part	NOUN
admet-2088	481	4	,	,	PUNCT
admet-2088	481	5	we	we	PRON
admet-2088	481	6	will	will	AUX
admet-2088	481	7	be	be	AUX
admet-2088	481	8	dividing	divide	VERB
admet-2088	481	9	polymeric	polymeric	ADJ
admet-2088	481	10	nps	nps	PROPN
admet-2088	481	11	into	into	ADP
admet-2088	481	12	two	two	NUM
admet-2088	481	13	categories	category	NOUN
admet-2088	481	14	based	base	VERB
admet-2088	481	15	on	on	ADP
admet-2088	481	16	their	their	PRON
admet-2088	481	17	constituents	constituent	NOUN
admet-2088	481	18	,	,	PUNCT
admet-2088	481	19	including	include	VERB
admet-2088	481	20	nanospheres	nanosphere	NOUN
admet-2088	481	21	,	,	PUNCT
admet-2088	481	22	nanocapsules	nanocapsule	NOUN
admet-2088	481	23	,	,	PUNCT
admet-2088	481	24	micelles	micelle	NOUN
admet-2088	481	25	,	,	PUNCT
admet-2088	481	26	dendrimers	dendrimer	NOUN
admet-2088	481	27	,	,	PUNCT
admet-2088	481	28	nanogel	nanogel	NOUN
admet-2088	481	29	,	,	PUNCT
admet-2088	481	30	nanocrystals	nanocrystal	NOUN
admet-2088	481	31	and	and	CCONJ
admet-2088	481	32	lipid	lipid	NOUN
admet-2088	481	33	-	-	PUNCT
admet-2088	481	34	based	base	VERB
admet-2088	481	35	nps	nps	PROPN
admet-2088	481	36	such	such	ADJ
admet-2088	481	37	as	as	ADP
admet-2088	481	38	nanoemulsions	nanoemulsion	NOUN
admet-2088	481	39	,	,	PUNCT
admet-2088	481	40	liposomes	liposome	NOUN
admet-2088	481	41	,	,	PUNCT
admet-2088	481	42	niosomes	niosome	NOUN
admet-2088	481	43	,	,	PUNCT
admet-2088	481	44	sln	sln	PROPN
admet-2088	481	45	and	and	CCONJ
admet-2088	481	46	exosomes	exosome	VERB
admet-2088	481	47	polymeric	polymeric	ADJ
admet-2088	481	48	nanospheres	nanosphere	NOUN
admet-2088	481	49	nanospheres	nanosphere	NOUN
admet-2088	481	50	are	be	AUX
admet-2088	481	51	spherical	spherical	ADJ
admet-2088	481	52	and	and	CCONJ
admet-2088	481	53	uniform	uniform	ADJ
admet-2088	481	54	-	-	PUNCT
admet-2088	481	55	sized	sized	ADJ
admet-2088	481	56	particles	particle	NOUN
admet-2088	481	57	and	and	CCONJ
admet-2088	481	58	comprise	comprise	VERB
admet-2088	481	59	either	either	CCONJ
admet-2088	481	60	biodegradable	biodegradable	ADJ
admet-2088	481	61	or	or	CCONJ
admet-2088	481	62	nonbiodegradable	nonbiodegradable	ADJ
admet-2088	481	63	polymers	polymer	NOUN
admet-2088	481	64	.	.	PUNCT
admet-2088	482	1	the	the	DET
admet-2088	482	2	drug	drug	NOUN
admet-2088	482	3	molecules	molecule	NOUN
admet-2088	482	4	are	be	AUX
admet-2088	482	5	evenly	evenly	ADV
admet-2088	482	6	distributed	distribute	VERB
admet-2088	482	7	throughout	throughout	ADP
admet-2088	482	8	the	the	DET
admet-2088	482	9	polymer	polymer	NOUN
admet-2088	482	10	matrix	matrix	NOUN
admet-2088	482	11	or	or	CCONJ
admet-2088	482	12	adsorbed	adsorb	VERB
admet-2088	482	13	on	on	ADP
admet-2088	482	14	the	the	DET
admet-2088	482	15	surface	surface	NOUN
admet-2088	482	16	,	,	PUNCT
admet-2088	482	17	resulting	result	VERB
admet-2088	482	18	in	in	ADP
admet-2088	482	19	a	a	DET
admet-2088	482	20	regulated	regulated	ADJ
admet-2088	482	21	release	release	NOUN
admet-2088	482	22	pattern	pattern	NOUN
admet-2088	482	23	[	[	X
admet-2088	482	24	180	180	NUM
admet-2088	482	25	]	]	PUNCT
admet-2088	482	26	.	.	PUNCT
admet-2088	483	1	the	the	DET
admet-2088	483	2	general	general	ADJ
admet-2088	483	3	method	method	NOUN
admet-2088	483	4	of	of	ADP
admet-2088	483	5	preparation	preparation	NOUN
admet-2088	483	6	involves	involve	VERB
admet-2088	483	7	the	the	DET
admet-2088	483	8	solubilization	solubilization	NOUN
admet-2088	483	9	of	of	ADP
admet-2088	483	10	monomers	monomer	NOUN
admet-2088	483	11	and	and	CCONJ
admet-2088	483	12	drugs	drug	NOUN
admet-2088	483	13	in	in	ADP
admet-2088	483	14	a	a	DET
admet-2088	483	15	suitable	suitable	ADJ
admet-2088	483	16	solvent	solvent	NOUN
admet-2088	483	17	,	,	PUNCT
admet-2088	483	18	followed	follow	VERB
admet-2088	483	19	by	by	ADP
admet-2088	483	20	the	the	DET
admet-2088	483	21	induction	induction	NOUN
admet-2088	483	22	of	of	ADP
admet-2088	483	23	crosslinking	crosslinke	VERB
admet-2088	483	24	of	of	ADP
admet-2088	483	25	monomers	monomer	NOUN
admet-2088	483	26	,	,	PUNCT
admet-2088	483	27	thus	thus	ADV
admet-2088	483	28	entrapping	entrap	VERB
admet-2088	483	29	the	the	DET
admet-2088	483	30	drug	drug	NOUN
admet-2088	483	31	molecules	molecule	NOUN
admet-2088	483	32	inside	inside	ADP
admet-2088	483	33	the	the	DET
admet-2088	483	34	matrix	matrix	NOUN
admet-2088	483	35	[	[	X
admet-2088	483	36	25	25	NUM
admet-2088	483	37	]	]	PUNCT
admet-2088	483	38	.	.	PUNCT
admet-2088	484	1	these	these	DET
admet-2088	484	2	nps	nps	PROPN
admet-2088	484	3	allow	allow	VERB
admet-2088	484	4	surface	surface	NOUN
admet-2088	484	5	modification	modification	NOUN
admet-2088	484	6	to	to	PART
admet-2088	484	7	improve	improve	VERB
admet-2088	484	8	their	their	PRON
admet-2088	484	9	drug	drug	NOUN
admet-2088	484	10	-	-	PUNCT
admet-2088	484	11	targeting	target	VERB
admet-2088	484	12	efficiency	efficiency	NOUN
admet-2088	484	13	.	.	PUNCT
admet-2088	485	1	polymeric	polymeric	ADJ
admet-2088	485	2	nanocapsules	nanocapsule	NOUN
admet-2088	485	3	polymeric	polymeric	ADJ
admet-2088	485	4	nanocapsules	nanocapsule	NOUN
admet-2088	485	5	are	be	AUX
admet-2088	485	6	core	core	ADJ
admet-2088	485	7	-	-	PUNCT
admet-2088	485	8	shell	shell	NOUN
admet-2088	485	9	structures	structure	NOUN
admet-2088	485	10	with	with	ADP
admet-2088	485	11	the	the	DET
admet-2088	485	12	active	active	ADJ
admet-2088	485	13	drug	drug	NOUN
admet-2088	485	14	moiety	moiety	NOUN
admet-2088	485	15	inside	inside	ADP
admet-2088	485	16	the	the	DET
admet-2088	485	17	core	core	NOUN
admet-2088	485	18	or	or	CCONJ
admet-2088	485	19	reservoir	reservoir	NOUN
admet-2088	485	20	in	in	ADP
admet-2088	485	21	solid	solid	ADJ
admet-2088	485	22	,	,	PUNCT
admet-2088	485	23	oily	oily	ADJ
admet-2088	485	24	or	or	CCONJ
admet-2088	485	25	molecular	molecular	ADJ
admet-2088	485	26	dispersion	dispersion	NOUN
admet-2088	485	27	.	.	PUNCT
admet-2088	486	1	this	this	DET
admet-2088	486	2	core	core	NOUN
admet-2088	486	3	is	be	AUX
admet-2088	486	4	surrounded	surround	VERB
admet-2088	486	5	by	by	ADP
admet-2088	486	6	a	a	DET
admet-2088	486	7	polymeric	polymeric	ADJ
admet-2088	486	8	coating	coating	NOUN
admet-2088	486	9	or	or	CCONJ
admet-2088	486	10	a	a	DET
admet-2088	486	11	membrane	membrane	NOUN
admet-2088	486	12	[	[	X
admet-2088	486	13	181	181	NUM
admet-2088	486	14	]	]	PUNCT
admet-2088	486	15	.	.	PUNCT
admet-2088	487	1	the	the	DET
admet-2088	487	2	cavity	cavity	NOUN
admet-2088	487	3	or	or	CCONJ
admet-2088	487	4	the	the	DET
admet-2088	487	5	core	core	NOUN
admet-2088	487	6	allows	allow	VERB
admet-2088	487	7	a	a	DET
admet-2088	487	8	high	high	ADJ
admet-2088	487	9	payload	payload	NOUN
admet-2088	487	10	of	of	ADP
admet-2088	487	11	the	the	DET
admet-2088	487	12	drugs	drug	NOUN
admet-2088	487	13	and	and	CCONJ
admet-2088	487	14	the	the	DET
admet-2088	487	15	coating	coating	NOUN
admet-2088	487	16	provides	provide	VERB
admet-2088	487	17	a	a	DET
admet-2088	487	18	predetermined	predetermine	VERB
admet-2088	487	19	rate	rate	NOUN
admet-2088	487	20	of	of	ADP
admet-2088	487	21	drug	drug	NOUN
admet-2088	487	22	release	release	NOUN
admet-2088	487	23	.	.	PUNCT
admet-2088	488	1	they	they	PRON
admet-2088	488	2	are	be	AUX
admet-2088	488	3	developed	develop	VERB
admet-2088	488	4	employing	employ	VERB
admet-2088	488	5	methods	method	NOUN
admet-2088	488	6	such	such	ADJ
admet-2088	488	7	as	as	ADP
admet-2088	488	8	interfacial	interfacial	ADJ
admet-2088	488	9	deposition	deposition	NOUN
admet-2088	488	10	,	,	PUNCT
admet-2088	488	11	layer	layer	NOUN
admet-2088	488	12	-	-	PUNCT
admet-2088	488	13	by	by	ADP
admet-2088	488	14	-	-	PUNCT
admet-2088	488	15	layer	layer	NOUN
admet-2088	488	16	method	method	NOUN
admet-2088	488	17	,	,	PUNCT
admet-2088	488	18	nanoemulsion	nanoemulsion	NOUN
admet-2088	488	19	,	,	PUNCT
admet-2088	488	20	etc	etc	X
admet-2088	488	21	.	.	X
admet-2088	489	1	nanocapsules	nanocapsule	NOUN
admet-2088	489	2	are	be	AUX
admet-2088	489	3	widely	widely	ADV
admet-2088	489	4	used	use	VERB
admet-2088	489	5	in	in	ADP
admet-2088	489	6	the	the	DET
admet-2088	489	7	treatment	treatment	NOUN
admet-2088	489	8	of	of	ADP
admet-2088	489	9	skin	skin	NOUN
admet-2088	489	10	cancer	cancer	NOUN
admet-2088	489	11	therapy	therapy	NOUN
admet-2088	489	12	due	due	ADP
admet-2088	489	13	to	to	ADP
admet-2088	489	14	their	their	PRON
admet-2088	489	15	merits	merit	NOUN
admet-2088	489	16	,	,	PUNCT
admet-2088	489	17	such	such	ADJ
admet-2088	489	18	as	as	ADP
admet-2088	489	19	lower	low	ADJ
admet-2088	489	20	irritation	irritation	NOUN
admet-2088	489	21	scores	score	NOUN
admet-2088	489	22	and	and	CCONJ
admet-2088	489	23	enhanced	enhance	VERB
admet-2088	489	24	stability	stability	NOUN
admet-2088	489	25	[	[	X
admet-2088	489	26	182	182	NUM
admet-2088	489	27	]	]	PUNCT
admet-2088	489	28	.	.	PUNCT
admet-2088	490	1	in	in	ADP
admet-2088	490	2	order	order	NOUN
admet-2088	490	3	to	to	PART
admet-2088	490	4	improve	improve	VERB
admet-2088	490	5	upon	upon	SCONJ
admet-2088	490	6	the	the	DET
admet-2088	490	7	broad	broad	ADJ
admet-2088	490	8	applicability	applicability	NOUN
admet-2088	490	9	,	,	PUNCT
admet-2088	490	10	poor	poor	ADJ
admet-2088	490	11	water	water	NOUN
admet-2088	490	12	-	-	PUNCT
admet-2088	490	13	soluble	soluble	ADJ
admet-2088	490	14	curcumin	curcumin	NOUN
admet-2088	490	15	was	be	AUX
admet-2088	490	16	conjugated	conjugate	VERB
admet-2088	490	17	with	with	ADP
admet-2088	490	18	hydrophilic	hydrophilic	ADJ
admet-2088	490	19	copolymer	copolymer	NOUN
admet-2088	490	20	composed	compose	VERB
admet-2088	490	21	of	of	ADP
admet-2088	490	22	phenylboronic	phenylboronic	ADJ
admet-2088	490	23	acid	acid	NOUN
admet-2088	490	24	(	(	PUNCT
admet-2088	490	25	pba	pba	PROPN
admet-2088	490	26	)	)	PUNCT
admet-2088	490	27	and	and	CCONJ
admet-2088	490	28	2	2	NUM
admet-2088	490	29	-	-	PUNCT
admet-2088	490	30	aminoethylmethacrylate	aminoethylmethacrylate	NOUN
admet-2088	490	31	(	(	PUNCT
admet-2088	490	32	aema	aema	NOUN
admet-2088	490	33	)	)	PUNCT
admet-2088	490	34	via	via	ADP
admet-2088	490	35	covalent	covalent	ADJ
admet-2088	490	36	linkage	linkage	NOUN
admet-2088	490	37	between	between	ADP
admet-2088	490	38	the	the	DET
admet-2088	490	39	1,3	1,3	NUM
admet-2088	490	40	-	-	PUNCT
admet-2088	490	41	diketone	diketone	NOUN
admet-2088	490	42	group	group	NOUN
admet-2088	490	43	in	in	ADP
admet-2088	490	44	curcumin	curcumin	NOUN
admet-2088	490	45	and	and	CCONJ
admet-2088	490	46	pba	pba	PROPN
admet-2088	490	47	group	group	NOUN
admet-2088	490	48	.	.	PUNCT
admet-2088	491	1	this	this	DET
admet-2088	491	2	stable	stable	ADJ
admet-2088	491	3	conjugated	conjugate	VERB
admet-2088	491	4	nps	nps	PROPN
admet-2088	491	5	(	(	PUNCT
admet-2088	491	6	approximately	approximately	ADV
admet-2088	491	7	400	400	NUM
admet-2088	491	8	nm	nm	NOUN
admet-2088	491	9	)	)	PUNCT
admet-2088	491	10	at	at	ADP
admet-2088	491	11	ph	ph	NOUN
admet-2088	491	12	around	around	ADP
admet-2088	491	13	7.4	7.4	NUM
admet-2088	491	14	and	and	CCONJ
admet-2088	491	15	underwent	undergo	VERB
admet-2088	491	16	immediate	immediate	ADJ
admet-2088	491	17	decomposition	decomposition	NOUN
admet-2088	491	18	when	when	SCONJ
admet-2088	491	19	the	the	DET
admet-2088	491	20	ph	ph	NOUN
admet-2088	491	21	reached	reach	VERB
admet-2088	491	22	around	around	ADP
admet-2088	491	23	5.5	5.5	NUM
admet-2088	491	24	to	to	PART
admet-2088	491	25	release	release	VERB
admet-2088	491	26	the	the	DET
admet-2088	491	27	conjugated	conjugate	VERB
admet-2088	491	28	curcumin	curcumin	NOUN
admet-2088	491	29	.	.	PUNCT
admet-2088	492	1	these	these	DET
admet-2088	492	2	np	np	PROPN
admet-2088	492	3	systems	system	NOUN
admet-2088	492	4	selectively	selectively	ADV
admet-2088	492	5	killed	kill	VERB
admet-2088	492	6	more	more	ADJ
admet-2088	492	7	than	than	ADP
admet-2088	492	8	90	90	NUM
admet-2088	492	9	%	%	NOUN
admet-2088	492	10	of	of	ADP
admet-2088	492	11	human	human	ADJ
admet-2088	492	12	malignant	malignant	ADJ
admet-2088	492	13	melanoma	melanoma	NOUN
admet-2088	492	14	cells	cell	NOUN
admet-2088	492	15	(	(	PUNCT
admet-2088	492	16	a375	a375	PROPN
admet-2088	492	17	)	)	PUNCT
admet-2088	492	18	,	,	PUNCT
admet-2088	492	19	while	while	SCONJ
admet-2088	492	20	around	around	ADV
admet-2088	492	21	70	70	NUM
admet-2088	492	22	%	%	NOUN
admet-2088	492	23	of	of	ADP
admet-2088	492	24	the	the	DET
admet-2088	492	25	mice	mice	NOUN
admet-2088	492	26	-	-	PUNCT
admet-2088	492	27	derived	derive	VERB
admet-2088	492	28	fibroblast	fibroblast	ADJ
admet-2088	492	29	cells	cell	NOUN
admet-2088	492	30	(	(	PUNCT
admet-2088	492	31	l929	l929	PROPN
admet-2088	492	32	)	)	PUNCT
admet-2088	492	33	survived	survive	VERB
admet-2088	492	34	[	[	X
admet-2088	492	35	183	183	NUM
admet-2088	492	36	]	]	PUNCT
admet-2088	492	37	.	.	PUNCT
admet-2088	493	1	hybrid	hybrid	PROPN
admet-2088	493	2	nps	nps	PROPN
admet-2088	493	3	with	with	ADP
admet-2088	493	4	polymer	polymer	NOUN
admet-2088	493	5	core	core	NOUN
admet-2088	493	6	(	(	PUNCT
admet-2088	493	7	plga	plga	NOUN
admet-2088	493	8	)	)	PUNCT
admet-2088	493	9	and	and	CCONJ
admet-2088	493	10	lipid	lipid	PROPN
admet-2088	493	11	shell	shell	NOUN
admet-2088	493	12	composed	compose	VERB
admet-2088	493	13	of	of	ADP
admet-2088	493	14	hydrogenated	hydrogenate	VERB
admet-2088	493	15	soy	soy	NOUN
admet-2088	493	16	phosphatidylcholine	phosphatidylcholine	NOUN
admet-2088	493	17	,	,	PUNCT
admet-2088	493	18	cholesterol	cholesterol	NOUN
admet-2088	493	19	and	and	CCONJ
admet-2088	493	20	1,2https://doi.org/10.5599	1,2https://doi.org/10.5599	NUM
admet-2088	493	21	/	/	SYM
admet-2088	493	22	admet.2088	admet.2088	PROPN
admet-2088	493	23	m.	m.	NOUN
admet-2088	493	24	kulkarni	kulkarni	PROPN
admet-2088	493	25	et	et	PROPN
admet-2088	493	26	al	al	PROPN
admet-2088	493	27	.	.	PROPN
admet-2088	493	28	admet	admet	PROPN
admet-2088	493	29	&	&	CCONJ
admet-2088	493	30	dmpk	dmpk	PROPN
admet-2088	493	31	12(1	12(1	PROPN
admet-2088	493	32	)	)	PUNCT
admet-2088	493	33	(	(	PUNCT
admet-2088	493	34	2024	2024	NUM
admet-2088	493	35	)	)	PUNCT
admet-2088	493	36	107	107	NUM
admet-2088	493	37	-	-	SYM
admet-2088	493	38	150	150	NUM
admet-2088	493	39	126	126	NUM
admet-2088	493	40	disteroyl	disteroyl	NOUN
admet-2088	493	41	-	-	PUNCT
admet-2088	493	42	sn	sn	NOUN
admet-2088	493	43	-	-	PUNCT
admet-2088	493	44	glycero-3	glycero-3	NOUN
admet-2088	493	45	-	-	PUNCT
admet-2088	493	46	phosphaethanolamine	phosphaethanolamine	NOUN
admet-2088	493	47	-	-	PUNCT
admet-2088	493	48	n[succinyl	n[succinyl	NOUN
admet-2088	493	49	(	(	PUNCT
admet-2088	493	50	peg)-2000	peg)-2000	PROPN
admet-2088	493	51	,	,	PUNCT
admet-2088	493	52	followed	follow	VERB
admet-2088	493	53	by	by	ADP
admet-2088	493	54	vitamin	vitamin	NOUN
admet-2088	493	55	d3	d3	PROPN
admet-2088	493	56	functionalization	functionalization	NOUN
admet-2088	493	57	was	be	AUX
admet-2088	493	58	synthesized	synthesize	VERB
admet-2088	493	59	to	to	PART
admet-2088	493	60	target	target	VERB
admet-2088	493	61	vitamin	vitamin	NOUN
admet-2088	493	62	d	d	NOUN
admet-2088	493	63	receptor	receptor	NOUN
admet-2088	493	64	expressed	express	VERB
admet-2088	493	65	on	on	ADP
admet-2088	493	66	melanoma	melanoma	NOUN
admet-2088	493	67	cells	cell	NOUN
admet-2088	493	68	.	.	PUNCT
admet-2088	494	1	the	the	DET
admet-2088	494	2	hybrid	hybrid	ADJ
admet-2088	494	3	nps	nps	PROPN
admet-2088	494	4	showed	show	VERB
admet-2088	494	5	initial	initial	ADJ
admet-2088	494	6	burst	burst	ADJ
admet-2088	494	7	release	release	NOUN
admet-2088	494	8	within	within	ADP
admet-2088	494	9	24	24	NUM
admet-2088	494	10	hours	hour	NOUN
admet-2088	494	11	and	and	CCONJ
admet-2088	494	12	thereafter	thereafter	ADV
admet-2088	494	13	diffusive	diffusive	ADJ
admet-2088	494	14	transport	transport	NOUN
admet-2088	494	15	in	in	ADP
admet-2088	494	16	vitro	vitro	VERB
admet-2088	494	17	.	.	PUNCT
admet-2088	495	1	they	they	PRON
admet-2088	495	2	were	be	AUX
admet-2088	495	3	found	find	VERB
admet-2088	495	4	to	to	PART
admet-2088	495	5	target	target	VERB
admet-2088	495	6	b16	b16	NOUN
admet-2088	495	7	melanoma	melanoma	NOUN
admet-2088	495	8	cells	cell	NOUN
admet-2088	495	9	efficiently	efficiently	ADV
admet-2088	495	10	and	and	CCONJ
admet-2088	495	11	thus	thus	ADV
admet-2088	495	12	can	can	AUX
admet-2088	495	13	act	act	VERB
admet-2088	495	14	as	as	ADP
admet-2088	495	15	a	a	DET
admet-2088	495	16	potential	potential	ADJ
admet-2088	495	17	carrier	carrier	NOUN
admet-2088	495	18	to	to	PART
admet-2088	495	19	deliver	deliver	VERB
admet-2088	495	20	therapeutics	therapeutic	NOUN
admet-2088	495	21	to	to	PART
admet-2088	495	22	treat	treat	VERB
admet-2088	495	23	melanoma	melanoma	NOUN
admet-2088	496	1	[	[	X
admet-2088	496	2	184	184	NUM
admet-2088	496	3	]	]	PUNCT
admet-2088	496	4	.	.	PUNCT
admet-2088	497	1	more	more	ADV
admet-2088	497	2	recently	recently	ADV
admet-2088	497	3	,	,	PUNCT
admet-2088	497	4	song	song	NOUN
admet-2088	497	5	et	et	PROPN
admet-2088	497	6	al	al	PROPN
admet-2088	497	7	.	.	PUNCT
admet-2088	498	1	[	[	X
admet-2088	498	2	185	185	NUM
admet-2088	498	3	]	]	PUNCT
admet-2088	498	4	fabricated	fabricate	VERB
admet-2088	498	5	polymeric	polymeric	ADJ
admet-2088	498	6	nps	nps	PROPN
admet-2088	498	7	with	with	ADP
admet-2088	498	8	il4rpep-1	il4rpep-1	ADJ
admet-2088	498	9	-	-	PUNCT
admet-2088	498	10	poly-(lactic	poly-(lactic	NOUN
admet-2088	498	11	-	-	PUNCT
admet-2088	498	12	co	co	NOUN
admet-2088	498	13	-	-	ADJ
admet-2088	498	14	glycolic	glycolic	ADJ
admet-2088	498	15	acid)grafted	acid)grafte	VERB
admet-2088	498	16	poly(ethylene	poly(ethylene	ADJ
admet-2088	498	17	glycol	glycol	NOUN
admet-2088	498	18	)	)	PUNCT
admet-2088	498	19	(	(	PUNCT
admet-2088	498	20	ipp	ipp	NOUN
admet-2088	498	21	)	)	PUNCT
admet-2088	498	22	copolymer	copolymer	NOUN
admet-2088	498	23	,	,	PUNCT
admet-2088	498	24	loaded	load	VERB
admet-2088	498	25	with	with	ADP
admet-2088	498	26	chemotherapeutic	chemotherapeutic	ADJ
admet-2088	498	27	agent	agent	NOUN
admet-2088	498	28	celecoxib	celecoxib	NOUN
admet-2088	498	29	and	and	CCONJ
admet-2088	498	30	immunotherapeutic	immunotherapeutic	ADJ
admet-2088	498	31	agent	agent	NOUN
admet-2088	498	32	afuresertib	afuresertib	VERB
admet-2088	498	33	to	to	PART
admet-2088	498	34	improve	improve	VERB
admet-2088	498	35	bioavailability	bioavailability	NOUN
admet-2088	498	36	and	and	CCONJ
admet-2088	498	37	to	to	PART
admet-2088	498	38	minimize	minimize	VERB
admet-2088	498	39	side	side	ADJ
admet-2088	498	40	effects	effect	NOUN
admet-2088	498	41	when	when	SCONJ
admet-2088	498	42	administered	administer	VERB
admet-2088	498	43	without	without	ADP
admet-2088	498	44	nanocarriers	nanocarrier	NOUN
admet-2088	498	45	.	.	PUNCT
admet-2088	499	1	the	the	DET
admet-2088	499	2	np	np	PROPN
admet-2088	499	3	system	system	NOUN
admet-2088	499	4	is	be	AUX
admet-2088	499	5	comprised	comprise	VERB
admet-2088	499	6	of	of	ADP
admet-2088	499	7	three	three	NUM
admet-2088	499	8	parts	part	NOUN
admet-2088	499	9	:	:	PUNCT
admet-2088	499	10	a	a	DET
admet-2088	499	11	hydrophobic	hydrophobic	NOUN
admet-2088	499	12	core	core	NOUN
admet-2088	499	13	of	of	ADP
admet-2088	499	14	plga	plga	NOUN
admet-2088	499	15	for	for	ADP
admet-2088	499	16	drug	drug	NOUN
admet-2088	499	17	loading	loading	NOUN
admet-2088	499	18	,	,	PUNCT
admet-2088	499	19	a	a	DET
admet-2088	499	20	hydrophilic	hydrophilic	ADJ
admet-2088	499	21	corona	corona	NOUN
admet-2088	499	22	of	of	ADP
admet-2088	499	23	peg	peg	NOUN
admet-2088	499	24	and	and	CCONJ
admet-2088	499	25	a	a	DET
admet-2088	499	26	targeting	targeting	NOUN
admet-2088	499	27	peptide	peptide	NOUN
admet-2088	499	28	il4rpep-1	il4rpep-1	ADP
admet-2088	499	29	which	which	PRON
admet-2088	499	30	improves	improve	VERB
admet-2088	499	31	the	the	DET
admet-2088	499	32	targeting	targeting	NOUN
admet-2088	499	33	potential	potential	NOUN
admet-2088	499	34	by	by	ADP
admet-2088	499	35	binding	bind	VERB
admet-2088	499	36	to	to	ADP
admet-2088	499	37	il-4	il-4	NOUN
admet-2088	499	38	receptor	receptor	NOUN
admet-2088	499	39	antigen	antigen	ADV
admet-2088	499	40	on	on	ADP
admet-2088	499	41	the	the	DET
admet-2088	499	42	surface	surface	NOUN
admet-2088	499	43	of	of	ADP
admet-2088	499	44	melanoma	melanoma	NOUN
admet-2088	499	45	tumour	tumour	ADJ
admet-2088	499	46	cells	cell	NOUN
admet-2088	499	47	.	.	PUNCT
admet-2088	500	1	these	these	DET
admet-2088	500	2	ipp	ipp	PROPN
admet-2088	500	3	nps	nps	PROPN
admet-2088	500	4	were	be	AUX
admet-2088	500	5	accumulated	accumulate	VERB
admet-2088	500	6	in	in	ADP
admet-2088	500	7	the	the	DET
admet-2088	500	8	melanoma	melanoma	NOUN
admet-2088	500	9	cells	cell	NOUN
admet-2088	500	10	via	via	ADP
admet-2088	500	11	epr	epr	PROPN
admet-2088	500	12	and	and	CCONJ
admet-2088	500	13	showed	show	VERB
admet-2088	500	14	an	an	DET
admet-2088	500	15	afuresertib	afuresertib	NOUN
admet-2088	500	16	-	-	PUNCT
admet-2088	500	17	mediated	mediate	VERB
admet-2088	500	18	reduction	reduction	NOUN
admet-2088	500	19	in	in	ADP
admet-2088	500	20	expression	expression	NOUN
admet-2088	500	21	and	and	CCONJ
admet-2088	500	22	phosphorylation	phosphorylation	NOUN
admet-2088	500	23	of	of	ADP
admet-2088	500	24	protein	protein	NOUN
admet-2088	500	25	-	-	PUNCT
admet-2088	500	26	kinase	kinase	NOUN
admet-2088	500	27	-	-	PUNCT
admet-2088	500	28	b	b	NOUN
admet-2088	500	29	in	in	ADP
admet-2088	500	30	tumour	tumour	ADJ
admet-2088	500	31	cells	cell	NOUN
admet-2088	500	32	.	.	PUNCT
admet-2088	501	1	this	this	PRON
admet-2088	501	2	led	lead	VERB
admet-2088	501	3	to	to	ADP
admet-2088	501	4	the	the	DET
admet-2088	501	5	enhancement	enhancement	NOUN
admet-2088	501	6	of	of	ADP
admet-2088	501	7	apoptosis	apoptosis	NOUN
admet-2088	501	8	of	of	ADP
admet-2088	501	9	melanoma	melanoma	NOUN
admet-2088	501	10	cells	cell	NOUN
admet-2088	501	11	and	and	CCONJ
admet-2088	501	12	the	the	DET
admet-2088	501	13	precise	precise	ADJ
admet-2088	501	14	regulation	regulation	NOUN
admet-2088	501	15	of	of	ADP
admet-2088	501	16	m2	m2	PROPN
admet-2088	501	17	macrophages	macrophage	NOUN
admet-2088	501	18	in	in	ADP
admet-2088	501	19	tumour	tumour	NOUN
admet-2088	501	20	cells	cell	NOUN
admet-2088	501	21	to	to	ADP
admet-2088	501	22	reprogram	reprogram	NOUN
admet-2088	501	23	m1	m1	PROPN
admet-2088	501	24	macrophages	macrophage	NOUN
admet-2088	501	25	resulting	result	VERB
admet-2088	501	26	in	in	ADP
admet-2088	501	27	the	the	DET
admet-2088	501	28	enhancement	enhancement	NOUN
admet-2088	501	29	of	of	ADP
admet-2088	501	30	immune	immune	ADJ
admet-2088	501	31	response	response	NOUN
admet-2088	501	32	and	and	CCONJ
admet-2088	501	33	inhibition	inhibition	NOUN
admet-2088	501	34	of	of	ADP
admet-2088	501	35	tumour	tumour	NOUN
admet-2088	501	36	growth	growth	NOUN
admet-2088	501	37	by	by	ADP
admet-2088	501	38	celecoxib	celecoxib	NOUN
admet-2088	501	39	.	.	PUNCT
admet-2088	502	1	thus	thus	ADV
admet-2088	502	2	,	,	PUNCT
admet-2088	502	3	the	the	DET
admet-2088	502	4	polymeric	polymeric	ADJ
admet-2088	502	5	nps	nps	PROPN
admet-2088	502	6	delivered	deliver	VERB
admet-2088	502	7	chemoimmunotherapeutic	chemoimmunotherapeutic	ADJ
admet-2088	502	8	agents	agent	NOUN
admet-2088	502	9	employing	employ	VERB
admet-2088	502	10	both	both	CCONJ
admet-2088	502	11	spatial	spatial	ADJ
admet-2088	502	12	and	and	CCONJ
admet-2088	502	13	temporal	temporal	ADJ
admet-2088	502	14	networks	network	NOUN
admet-2088	502	15	and	and	CCONJ
admet-2088	502	16	can	can	AUX
admet-2088	502	17	be	be	AUX
admet-2088	502	18	great	great	ADJ
admet-2088	502	19	assets	asset	NOUN
admet-2088	502	20	for	for	ADP
admet-2088	502	21	the	the	DET
admet-2088	502	22	treatment	treatment	NOUN
admet-2088	502	23	of	of	ADP
admet-2088	502	24	ectopic	ectopic	ADJ
admet-2088	502	25	melanoma	melanoma	NOUN
admet-2088	502	26	.	.	PUNCT
admet-2088	503	1	dendrimers	dendrimer	NOUN
admet-2088	503	2	dendrimers	dendrimer	NOUN
admet-2088	503	3	are	be	AUX
admet-2088	503	4	3d	3d	NUM
admet-2088	503	5	spherical	spherical	ADJ
admet-2088	503	6	,	,	PUNCT
admet-2088	503	7	highly	highly	ADV
admet-2088	503	8	branched	branched	ADJ
admet-2088	503	9	,	,	PUNCT
admet-2088	503	10	unimolecular	unimolecular	ADJ
admet-2088	503	11	,	,	PUNCT
admet-2088	503	12	micellar	micellar	NOUN
admet-2088	503	13	structures	structure	NOUN
admet-2088	503	14	having	have	VERB
admet-2088	503	15	a	a	DET
admet-2088	503	16	size	size	NOUN
admet-2088	503	17	of	of	ADP
admet-2088	503	18	around	around	ADV
admet-2088	503	19	20	20	NUM
admet-2088	503	20	nm	nm	NOUN
admet-2088	503	21	[	[	X
admet-2088	503	22	186	186	NUM
admet-2088	503	23	]	]	PUNCT
admet-2088	503	24	.	.	PUNCT
admet-2088	504	1	basically	basically	ADV
admet-2088	504	2	,	,	PUNCT
admet-2088	504	3	the	the	DET
admet-2088	504	4	dendrimer	dendrimer	NOUN
admet-2088	504	5	structure	structure	NOUN
admet-2088	504	6	comprises	comprise	VERB
admet-2088	504	7	three	three	NUM
admet-2088	504	8	distinct	distinct	ADJ
admet-2088	504	9	regions	region	NOUN
admet-2088	504	10	:	:	PUNCT
admet-2088	504	11	a	a	DET
admet-2088	504	12	core	core	NOUN
admet-2088	504	13	or	or	CCONJ
admet-2088	504	14	a	a	DET
admet-2088	504	15	focal	focal	ADJ
admet-2088	504	16	moiety	moiety	NOUN
admet-2088	504	17	,	,	PUNCT
admet-2088	504	18	a	a	DET
admet-2088	504	19	welldefined	welldefine	VERB
admet-2088	504	20	regularly	regularly	ADV
admet-2088	504	21	branched	branched	ADJ
admet-2088	504	22	symmetrical	symmetrical	ADJ
admet-2088	504	23	repeated	repeat	VERB
admet-2088	504	24	structure	structure	NOUN
admet-2088	504	25	originating	originate	VERB
admet-2088	504	26	from	from	ADP
admet-2088	504	27	the	the	DET
admet-2088	504	28	core	core	NOUN
admet-2088	504	29	and	and	CCONJ
admet-2088	504	30	functional	functional	ADJ
admet-2088	504	31	end	end	NOUN
admet-2088	504	32	-	-	PUNCT
admet-2088	504	33	groups	group	NOUN
admet-2088	504	34	on	on	ADP
admet-2088	504	35	the	the	DET
admet-2088	504	36	outer	outer	ADJ
admet-2088	504	37	layer	layer	NOUN
admet-2088	504	38	of	of	ADP
admet-2088	504	39	repeated	repeat	VERB
admet-2088	504	40	units	unit	NOUN
admet-2088	504	41	[	[	X
admet-2088	504	42	187	187	NUM
admet-2088	504	43	]	]	PUNCT
admet-2088	504	44	.	.	PUNCT
admet-2088	505	1	these	these	DET
admet-2088	505	2	nps	nps	PROPN
admet-2088	505	3	have	have	VERB
admet-2088	505	4	numerous	numerous	ADJ
admet-2088	505	5	advantages	advantage	NOUN
admet-2088	505	6	over	over	ADP
admet-2088	505	7	other	other	ADJ
admet-2088	505	8	nanocarriers	nanocarrier	NOUN
admet-2088	505	9	,	,	PUNCT
admet-2088	505	10	including	include	VERB
admet-2088	505	11	vast	vast	ADJ
admet-2088	505	12	internal	internal	ADJ
admet-2088	505	13	cavities	cavity	NOUN
admet-2088	505	14	and	and	CCONJ
admet-2088	505	15	a	a	DET
admet-2088	505	16	higher	high	ADJ
admet-2088	505	17	degree	degree	NOUN
admet-2088	505	18	of	of	ADP
admet-2088	505	19	branching	branch	VERB
admet-2088	505	20	,	,	PUNCT
admet-2088	505	21	allowing	allow	VERB
admet-2088	505	22	high	high	ADJ
admet-2088	505	23	drug	drug	NOUN
admet-2088	505	24	payload	payload	NOUN
admet-2088	505	25	,	,	PUNCT
admet-2088	505	26	structural	structural	ADJ
admet-2088	505	27	feasibility	feasibility	NOUN
admet-2088	505	28	in	in	ADP
admet-2088	505	29	size	size	NOUN
admet-2088	505	30	and	and	CCONJ
admet-2088	505	31	molecular	molecular	ADJ
admet-2088	505	32	weight	weight	NOUN
admet-2088	505	33	,	,	PUNCT
admet-2088	505	34	and	and	CCONJ
admet-2088	505	35	monodisperse	monodisperse	NOUN
admet-2088	505	36	properties	property	NOUN
admet-2088	505	37	along	along	ADP
admet-2088	505	38	multivalent	multivalent	NOUN
admet-2088	505	39	characteristics	characteristic	NOUN
admet-2088	505	40	[	[	X
admet-2088	505	41	50	50	NUM
admet-2088	505	42	]	]	PUNCT
admet-2088	505	43	.	.	PUNCT
admet-2088	506	1	the	the	DET
admet-2088	506	2	flexibility	flexibility	NOUN
admet-2088	506	3	of	of	ADP
admet-2088	506	4	adjustment	adjustment	NOUN
admet-2088	506	5	of	of	ADP
admet-2088	506	6	critical	critical	ADJ
admet-2088	506	7	properties	property	NOUN
admet-2088	506	8	such	such	ADJ
admet-2088	506	9	as	as	ADP
admet-2088	506	10	size	size	NOUN
admet-2088	506	11	,	,	PUNCT
admet-2088	506	12	surface	surface	NOUN
admet-2088	506	13	topology	topology	NOUN
admet-2088	506	14	,	,	PUNCT
admet-2088	506	15	architecture	architecture	NOUN
admet-2088	506	16	,	,	PUNCT
admet-2088	506	17	solubility	solubility	NOUN
admet-2088	506	18	and	and	CCONJ
admet-2088	506	19	chemical	chemical	NOUN
admet-2088	506	20	constitution	constitution	NOUN
admet-2088	506	21	make	make	VERB
admet-2088	506	22	dendrimers	dendrimer	NOUN
admet-2088	506	23	a	a	DET
admet-2088	506	24	versatile	versatile	ADJ
admet-2088	506	25	nanocarrier	nanocarrier	NOUN
admet-2088	506	26	.	.	PUNCT
admet-2088	507	1	in	in	ADP
admet-2088	507	2	addition	addition	NOUN
admet-2088	507	3	,	,	PUNCT
admet-2088	507	4	they	they	PRON
admet-2088	507	5	are	be	AUX
admet-2088	507	6	capable	capable	ADJ
admet-2088	507	7	of	of	ADP
admet-2088	507	8	entrapping	entrap	VERB
admet-2088	507	9	both	both	CCONJ
admet-2088	507	10	hydrophilic	hydrophilic	ADJ
admet-2088	507	11	and	and	CCONJ
admet-2088	507	12	lipophilic	lipophilic	ADJ
admet-2088	507	13	drugs	drug	NOUN
admet-2088	507	14	due	due	ADP
admet-2088	507	15	to	to	ADP
admet-2088	507	16	the	the	DET
admet-2088	507	17	presence	presence	NOUN
admet-2088	507	18	of	of	ADP
admet-2088	507	19	a	a	DET
admet-2088	507	20	hydrophilic	hydrophilic	ADJ
admet-2088	507	21	surface	surface	NOUN
admet-2088	507	22	and	and	CCONJ
admet-2088	507	23	hydrophobic	hydrophobic	NOUN
admet-2088	507	24	core	core	NOUN
admet-2088	507	25	.	.	PUNCT
admet-2088	508	1	moreover	moreover	ADV
admet-2088	508	2	,	,	PUNCT
admet-2088	508	3	drugs	drug	NOUN
admet-2088	508	4	can	can	AUX
admet-2088	508	5	be	be	AUX
admet-2088	508	6	physically	physically	ADV
admet-2088	508	7	encapsulated	encapsulate	VERB
admet-2088	508	8	into	into	ADP
admet-2088	508	9	the	the	DET
admet-2088	508	10	void	void	ADJ
admet-2088	508	11	space	space	NOUN
admet-2088	508	12	or	or	CCONJ
admet-2088	508	13	covalently	covalently	ADV
admet-2088	508	14	bonded	bond	VERB
admet-2088	508	15	on	on	ADP
admet-2088	508	16	the	the	DET
admet-2088	508	17	surface	surface	NOUN
admet-2088	508	18	with	with	ADP
admet-2088	508	19	functional	functional	ADJ
admet-2088	508	20	groups	group	NOUN
admet-2088	508	21	[	[	X
admet-2088	508	22	188	188	NUM
admet-2088	508	23	]	]	PUNCT
admet-2088	508	24	.	.	PUNCT
admet-2088	509	1	biocompatibility	biocompatibility	NOUN
admet-2088	509	2	and	and	CCONJ
admet-2088	509	3	cancer	cancer	NOUN
admet-2088	509	4	specificity	specificity	NOUN
admet-2088	509	5	can	can	AUX
admet-2088	509	6	be	be	AUX
admet-2088	509	7	incorporated	incorporate	VERB
admet-2088	509	8	into	into	ADP
admet-2088	509	9	dendrimers	dendrimer	NOUN
admet-2088	509	10	through	through	ADP
admet-2088	509	11	surface	surface	NOUN
admet-2088	509	12	modification	modification	NOUN
admet-2088	509	13	and	and	CCONJ
admet-2088	509	14	attaching	attach	VERB
admet-2088	509	15	suitable	suitable	ADJ
admet-2088	509	16	ligands	ligand	NOUN
admet-2088	509	17	.	.	PUNCT
admet-2088	510	1	they	they	PRON
admet-2088	510	2	are	be	AUX
admet-2088	510	3	capable	capable	ADJ
admet-2088	510	4	of	of	ADP
admet-2088	510	5	delivering	deliver	VERB
admet-2088	510	6	the	the	DET
admet-2088	510	7	loaded	load	VERB
admet-2088	510	8	drugs	drug	NOUN
admet-2088	510	9	in	in	ADP
admet-2088	510	10	a	a	DET
admet-2088	510	11	controlled	control	VERB
admet-2088	510	12	manner	manner	NOUN
admet-2088	510	13	and	and	CCONJ
admet-2088	510	14	at	at	ADP
admet-2088	510	15	the	the	DET
admet-2088	510	16	specific	specific	ADJ
admet-2088	510	17	site	site	NOUN
admet-2088	510	18	.	.	PUNCT
admet-2088	511	1	dendrimers	dendrimer	NOUN
admet-2088	511	2	are	be	AUX
admet-2088	511	3	internalized	internalize	VERB
admet-2088	511	4	through	through	ADP
admet-2088	511	5	cellular	cellular	ADJ
admet-2088	511	6	endocytosis	endocytosis	NOUN
admet-2088	511	7	,	,	PUNCT
admet-2088	511	8	thus	thus	ADV
admet-2088	511	9	promoting	promote	VERB
admet-2088	511	10	the	the	DET
admet-2088	511	11	transit	transit	NOUN
admet-2088	511	12	of	of	ADP
admet-2088	511	13	medicines	medicine	NOUN
admet-2088	511	14	through	through	ADP
admet-2088	511	15	different	different	ADJ
admet-2088	511	16	types	type	NOUN
admet-2088	511	17	of	of	ADP
admet-2088	511	18	cell	cell	NOUN
admet-2088	511	19	membranes	membrane	NOUN
admet-2088	511	20	or	or	CCONJ
admet-2088	511	21	biological	biological	ADJ
admet-2088	511	22	barriers	barrier	NOUN
admet-2088	511	23	[	[	X
admet-2088	511	24	5	5	NUM
admet-2088	511	25	]	]	PUNCT
admet-2088	511	26	.	.	PUNCT
admet-2088	512	1	jiang	jiang	PROPN
admet-2088	512	2	et	et	PROPN
admet-2088	512	3	al	al	PROPN
admet-2088	512	4	.	.	PUNCT
admet-2088	513	1	[	[	X
admet-2088	513	2	189	189	NUM
admet-2088	513	3	]	]	PUNCT
admet-2088	513	4	have	have	AUX
admet-2088	513	5	fabricated	fabricate	VERB
admet-2088	513	6	polyamide	polyamide	NOUN
admet-2088	513	7	amine	amine	NOUN
admet-2088	513	8	dendrimer	dendrimer	NOUN
admet-2088	513	9	(	(	PUNCT
admet-2088	513	10	pamam)-peg	pamam)-peg	NOUN
admet-2088	513	11	-	-	PUNCT
admet-2088	513	12	ge11	ge11	PROPN
admet-2088	513	13	-	-	PUNCT
admet-2088	513	14	ha	ha	INTJ
admet-2088	513	15	conjugates	conjugate	NOUN
admet-2088	513	16	loaded	load	VERB
admet-2088	513	17	with	with	ADP
admet-2088	513	18	temozolomide	temozolomide	NOUN
admet-2088	513	19	for	for	ADP
admet-2088	513	20	their	their	PRON
admet-2088	513	21	targeting	targeting	NOUN
admet-2088	513	22	potential	potential	NOUN
admet-2088	513	23	towards	towards	ADP
admet-2088	513	24	melanoma	melanoma	NOUN
admet-2088	513	25	cells	cell	NOUN
admet-2088	513	26	.	.	PUNCT
admet-2088	514	1	here	here	ADV
admet-2088	514	2	,	,	PUNCT
admet-2088	514	3	ge11	ge11	PROPN
admet-2088	514	4	acted	act	VERB
admet-2088	514	5	as	as	ADP
admet-2088	514	6	an	an	DET
admet-2088	514	7	active	active	ADJ
admet-2088	514	8	targeting	target	VERB
admet-2088	514	9	agent	agent	NOUN
admet-2088	514	10	in	in	ADP
admet-2088	514	11	antitumor	antitumor	PROPN
admet-2088	514	12	therapy	therapy	NOUN
admet-2088	514	13	.	.	PUNCT
admet-2088	515	1	this	this	DET
admet-2088	515	2	dendrimer	dendrimer	NOUN
admet-2088	515	3	-	-	PUNCT
admet-2088	515	4	based	base	VERB
admet-2088	515	5	nano	nano	NOUN
admet-2088	515	6	-	-	PUNCT
admet-2088	515	7	dds	dds	PROPN
admet-2088	515	8	was	be	AUX
admet-2088	515	9	developed	develop	VERB
admet-2088	515	10	by	by	ADP
admet-2088	515	11	ultrasonic	ultrasonic	ADJ
admet-2088	515	12	emulsification	emulsification	NOUN
admet-2088	515	13	and	and	CCONJ
admet-2088	515	14	demonstrated	demonstrate	VERB
admet-2088	515	15	suitable	suitable	ADJ
admet-2088	515	16	characteristics	characteristic	NOUN
admet-2088	515	17	such	such	ADJ
admet-2088	515	18	as	as	ADP
admet-2088	515	19	a	a	DET
admet-2088	515	20	mean	mean	ADJ
admet-2088	515	21	particle	particle	NOUN
admet-2088	515	22	size	size	NOUN
admet-2088	515	23	of	of	ADP
admet-2088	515	24	183.2	183.2	NUM
admet-2088	515	25	nm	nm	NOUN
admet-2088	515	26	,	,	PUNCT
admet-2088	515	27	a	a	DET
admet-2088	515	28	regular	regular	ADJ
admet-2088	515	29	sphere	sphere	NOUN
admet-2088	515	30	with	with	ADP
admet-2088	515	31	good	good	ADJ
admet-2088	515	32	uniformity	uniformity	NOUN
admet-2088	515	33	,	,	PUNCT
admet-2088	515	34	zeta	zeta	NOUN
admet-2088	515	35	potential	potential	NOUN
admet-2088	515	36	of	of	ADP
admet-2088	515	37	-0.01	-0.01	NUM
admet-2088	515	38	mv	mv	PROPN
admet-2088	515	39	,	,	PUNCT
admet-2088	515	40	entrapment	entrapment	ADJ
admet-2088	515	41	efficiency	efficiency	NOUN
admet-2088	515	42	of	of	ADP
admet-2088	515	43	50.63	50.63	PRON
admet-2088	515	44	%	%	NOUN
admet-2088	515	45	and	and	CCONJ
admet-2088	515	46	drug	drug	NOUN
admet-2088	515	47	loading	loading	NOUN
admet-2088	515	48	of	of	ADP
admet-2088	515	49	10.4	10.4	DET
admet-2088	515	50	%	%	NOUN
admet-2088	515	51	.	.	PUNCT
admet-2088	516	1	this	this	DET
admet-2088	516	2	nano	nano	NOUN
admet-2088	516	3	-	-	PUNCT
admet-2088	516	4	dds	dds	PROPN
admet-2088	516	5	showed	show	VERB
admet-2088	516	6	potential	potential	ADJ
admet-2088	516	7	targeting	targeting	NOUN
admet-2088	516	8	towards	towards	ADP
admet-2088	516	9	a375	a375	PROPN
admet-2088	516	10	human	human	ADJ
admet-2088	516	11	melanoma	melanoma	NOUN
admet-2088	516	12	cells	cell	NOUN
admet-2088	516	13	with	with	ADP
admet-2088	516	14	minimal	minimal	ADJ
admet-2088	516	15	absorption	absorption	NOUN
admet-2088	516	16	into	into	ADP
admet-2088	516	17	the	the	DET
admet-2088	516	18	normal	normal	ADJ
admet-2088	516	19	cells	cell	NOUN
admet-2088	516	20	.	.	PUNCT
admet-2088	517	1	most	most	ADV
admet-2088	517	2	recently	recently	ADV
admet-2088	517	3	,	,	PUNCT
admet-2088	517	4	russi	russi	PROPN
admet-2088	517	5	et	et	PROPN
admet-2088	517	6	al	al	PROPN
admet-2088	517	7	.	.	PUNCT
admet-2088	518	1	[	[	X
admet-2088	518	2	7	7	NUM
admet-2088	518	3	]	]	PUNCT
admet-2088	518	4	investigated	investigate	VERB
admet-2088	518	5	the	the	DET
admet-2088	518	6	targeting	targeting	NOUN
admet-2088	518	7	of	of	ADP
admet-2088	518	8	braf	braf	NOUN
admet-2088	518	9	in	in	ADP
admet-2088	518	10	melanoma	melanoma	NOUN
admet-2088	518	11	patients	patient	NOUN
admet-2088	518	12	with	with	ADP
admet-2088	518	13	braf	braf	NOUN
admet-2088	518	14	inhibitors	inhibitor	NOUN
admet-2088	518	15	dabrafenib	dabrafenib	NOUN
admet-2088	518	16	and	and	CCONJ
admet-2088	518	17	vemurafenib	vemurafenib	NOUN
admet-2088	518	18	by	by	ADP
admet-2088	518	19	successfully	successfully	ADV
admet-2088	518	20	encapsulating	encapsulate	VERB
admet-2088	518	21	them	they	PRON
admet-2088	518	22	into	into	ADP
admet-2088	518	23	core	core	NOUN
admet-2088	518	24	-	-	PUNCT
admet-2088	518	25	shell	shell	NOUN
admet-2088	518	26	nano	nano	NOUN
admet-2088	518	27	-	-	PUNCT
admet-2088	518	28	micelles	micelle	NOUN
admet-2088	518	29	of	of	ADP
admet-2088	518	30	an	an	DET
admet-2088	518	31	amphiphilic	amphiphilic	ADJ
admet-2088	518	32	dendrimer	dendrimer	NOUN
admet-2088	518	33	-	-	PUNCT
admet-2088	518	34	based	base	VERB
admet-2088	518	35	on	on	ADP
admet-2088	518	36	g2	g2	PROPN
admet-2088	518	37	pamam	pamam	NOUN
admet-2088	518	38	head	head	NOUN
admet-2088	518	39	and	and	CCONJ
admet-2088	518	40	c18	c18	NOUN
admet-2088	518	41	aliphatic	aliphatic	ADJ
admet-2088	518	42	chains	chain	NOUN
admet-2088	518	43	.	.	PUNCT
admet-2088	519	1	encapsulation	encapsulation	NOUN
admet-2088	519	2	of	of	ADP
admet-2088	519	3	braf	braf	NOUN
admet-2088	519	4	inhibitors	inhibitor	NOUN
admet-2088	519	5	in	in	ADP
admet-2088	519	6	dendrimer	dendrimer	NOUN
admet-2088	519	7	was	be	AUX
admet-2088	519	8	found	find	VERB
admet-2088	519	9	to	to	PART
admet-2088	519	10	improve	improve	VERB
admet-2088	519	11	tissue	tissue	NOUN
admet-2088	519	12	permeability	permeability	NOUN
admet-2088	519	13	and	and	CCONJ
admet-2088	519	14	extend	extend	VERB
admet-2088	519	15	the	the	DET
admet-2088	519	16	systemic	systemic	ADJ
admet-2088	519	17	drug	drug	NOUN
admet-2088	519	18	circulation	circulation	NOUN
admet-2088	519	19	,	,	PUNCT
admet-2088	519	20	extended	extended	ADJ
admet-2088	519	21	-	-	PUNCT
admet-2088	519	22	release	release	NOUN
admet-2088	519	23	at	at	ADP
admet-2088	519	24	the	the	DET
admet-2088	519	25	targeted	target	VERB
admet-2088	519	26	site	site	NOUN
admet-2088	519	27	,	,	PUNCT
admet-2088	519	28	thereby	thereby	ADV
admet-2088	519	29	reducing	reduce	VERB
admet-2088	519	30	systemic	systemic	ADJ
admet-2088	519	31	toxicity	toxicity	NOUN
admet-2088	519	32	associated	associate	VERB
admet-2088	519	33	with	with	ADP
admet-2088	519	34	chemotherapeutics	chemotherapeutic	NOUN
admet-2088	519	35	.	.	PUNCT
admet-2088	520	1	developed	develop	VERB
admet-2088	520	2	nano	nano	NOUN
admet-2088	520	3	-	-	PUNCT
admet-2088	520	4	micelles	micelle	NOUN
admet-2088	520	5	(	(	PUNCT
admet-2088	520	6	10	10	PROPN
admet-2088	520	7	nm	nm	NOUN
admet-2088	520	8	)	)	PUNCT
admet-2088	520	9	showed	show	VERB
admet-2088	520	10	excellent	excellent	ADJ
admet-2088	520	11	encapsulation	encapsulation	NOUN
admet-2088	520	12	efficiency	efficiency	NOUN
admet-2088	520	13	with	with	ADP
admet-2088	520	14	good	good	ADJ
admet-2088	520	15	drug	drug	NOUN
admet-2088	520	16	-	-	PUNCT
admet-2088	520	17	loading	loading	NOUN
admet-2088	520	18	ability	ability	NOUN
admet-2088	520	19	.	.	PUNCT
admet-2088	521	1	admet	admet	PROPN
admet-2088	521	2	&	&	CCONJ
admet-2088	521	3	dmpk	dmpk	PROPN
admet-2088	521	4	12(1	12(1	PROPN
admet-2088	521	5	)	)	PUNCT
admet-2088	521	6	(	(	PUNCT
admet-2088	521	7	2024	2024	NUM
admet-2088	521	8	)	)	PUNCT
admet-2088	521	9	107	107	NUM
admet-2088	521	10	-	-	SYM
admet-2088	521	11	150	150	NUM
admet-2088	521	12	nanomaterial	nanomaterial	NOUN
admet-2088	521	13	-	-	PUNCT
admet-2088	521	14	based	base	VERB
admet-2088	521	15	drug	drug	NOUN
admet-2088	521	16	delivery	delivery	NOUN
admet-2088	521	17	systems	system	NOUN
admet-2088	521	18	for	for	ADP
admet-2088	521	19	melanoma	melanoma	NOUN
admet-2088	521	20	therapy	therapy	NOUN
admet-2088	521	21	doi	doi	NOUN
admet-2088	521	22	:	:	PUNCT
admet-2088	521	23	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	521	24	127	127	NUM
admet-2088	521	25	further	far	ADV
admet-2088	521	26	,	,	PUNCT
admet-2088	521	27	the	the	DET
admet-2088	521	28	release	release	NOUN
admet-2088	521	29	of	of	ADP
admet-2088	521	30	both	both	DET
admet-2088	521	31	drugs	drug	NOUN
admet-2088	521	32	from	from	ADP
admet-2088	521	33	nano	nano	NOUN
admet-2088	521	34	-	-	PUNCT
admet-2088	521	35	micelles	micelle	NOUN
admet-2088	521	36	was	be	AUX
admet-2088	521	37	enhanced	enhance	VERB
admet-2088	521	38	at	at	ADP
admet-2088	521	39	an	an	DET
admet-2088	521	40	acidic	acidic	ADJ
admet-2088	521	41	ph	ph	NOUN
admet-2088	521	42	of	of	ADP
admet-2088	521	43	5.0	5.0	NUM
admet-2088	521	44	in	in	ADP
admet-2088	521	45	vitro	vitro	X
admet-2088	521	46	.	.	PUNCT
admet-2088	522	1	when	when	SCONJ
admet-2088	522	2	tested	test	VERB
admet-2088	522	3	on	on	ADP
admet-2088	522	4	melanoma	melanoma	NOUN
admet-2088	522	5	cell	cell	NOUN
admet-2088	522	6	lines	line	NOUN
admet-2088	522	7	,	,	PUNCT
admet-2088	522	8	both	both	DET
admet-2088	522	9	drugs	drug	NOUN
admet-2088	522	10	showed	show	VERB
admet-2088	522	11	enhanced	enhanced	ADJ
admet-2088	522	12	response	response	NOUN
admet-2088	522	13	in	in	ADP
admet-2088	522	14	comparison	comparison	NOUN
admet-2088	522	15	to	to	ADP
admet-2088	522	16	free	free	ADJ
admet-2088	522	17	drug	drug	NOUN
admet-2088	522	18	treatment	treatment	NOUN
admet-2088	522	19	.	.	PUNCT
admet-2088	523	1	polymeric	polymeric	ADJ
admet-2088	523	2	micelles	micelle	NOUN
admet-2088	523	3	polymeric	polymeric	ADJ
admet-2088	523	4	micelles	micelle	NOUN
admet-2088	523	5	are	be	AUX
admet-2088	523	6	nanoscale	nanoscale	NOUN
admet-2088	523	7	(	(	PUNCT
admet-2088	523	8	10	10	NUM
admet-2088	523	9	-	-	SYM
admet-2088	523	10	100	100	NUM
admet-2088	523	11	nm	nm	NOUN
admet-2088	523	12	)	)	PUNCT
admet-2088	523	13	core	core	ADJ
admet-2088	523	14	-	-	PUNCT
admet-2088	523	15	shell	shell	NOUN
admet-2088	523	16	structures	structure	NOUN
admet-2088	523	17	comprised	comprise	VERB
admet-2088	523	18	of	of	ADP
admet-2088	523	19	spontaneous	spontaneous	ADJ
admet-2088	523	20	selfassembly	selfassembly	NOUN
admet-2088	523	21	of	of	ADP
admet-2088	523	22	individual	individual	ADJ
admet-2088	523	23	di	di	PROPN
admet-2088	523	24	/	/	SYM
admet-2088	523	25	tri	tri	ADJ
admet-2088	523	26	-	-	ADJ
admet-2088	523	27	block	block	ADJ
admet-2088	523	28	copolymers	copolymer	NOUN
admet-2088	523	29	in	in	ADP
admet-2088	523	30	aqueous	aqueous	ADJ
admet-2088	523	31	medium	medium	NOUN
admet-2088	523	32	[	[	X
admet-2088	523	33	186	186	NUM
admet-2088	523	34	]	]	PUNCT
admet-2088	523	35	.	.	PUNCT
admet-2088	524	1	the	the	DET
admet-2088	524	2	structure	structure	NOUN
admet-2088	524	3	has	have	VERB
admet-2088	524	4	a	a	DET
admet-2088	524	5	lipophilic	lipophilic	ADJ
admet-2088	524	6	core	core	NOUN
admet-2088	524	7	that	that	PRON
admet-2088	524	8	can	can	AUX
admet-2088	524	9	entrap	entrap	VERB
admet-2088	524	10	hydrophobic	hydrophobic	NOUN
admet-2088	524	11	drugs	drug	NOUN
admet-2088	524	12	and	and	CCONJ
admet-2088	524	13	a	a	DET
admet-2088	524	14	hydrophilic	hydrophilic	ADJ
admet-2088	524	15	shell	shell	NOUN
admet-2088	524	16	,	,	PUNCT
admet-2088	524	17	generally	generally	ADV
admet-2088	524	18	formed	form	VERB
admet-2088	524	19	of	of	ADP
admet-2088	524	20	peg	peg	NOUN
admet-2088	524	21	,	,	PUNCT
admet-2088	524	22	which	which	PRON
admet-2088	524	23	prevents	prevent	VERB
admet-2088	524	24	the	the	DET
admet-2088	524	25	aggregation	aggregation	NOUN
admet-2088	524	26	of	of	ADP
admet-2088	524	27	micelles	micelle	NOUN
admet-2088	524	28	and	and	CCONJ
admet-2088	524	29	helps	help	VERB
admet-2088	524	30	prolong	prolong	VERB
admet-2088	524	31	the	the	DET
admet-2088	524	32	circulation	circulation	NOUN
admet-2088	524	33	time	time	NOUN
admet-2088	524	34	in	in	ADP
admet-2088	524	35	the	the	DET
admet-2088	524	36	blood	blood	NOUN
admet-2088	525	1	[	[	X
admet-2088	525	2	190	190	NUM
admet-2088	525	3	]	]	PUNCT
admet-2088	525	4	.	.	PUNCT
admet-2088	526	1	polymeric	polymeric	ADJ
admet-2088	526	2	micelles	micelle	NOUN
admet-2088	526	3	possess	possess	VERB
admet-2088	526	4	characteristic	characteristic	ADJ
admet-2088	526	5	features	feature	NOUN
admet-2088	526	6	such	such	ADJ
admet-2088	526	7	as	as	ADP
admet-2088	526	8	nano	nano	NOUN
admet-2088	526	9	-	-	PUNCT
admet-2088	526	10	size	size	NOUN
admet-2088	526	11	,	,	PUNCT
admet-2088	526	12	appropriate	appropriate	ADJ
admet-2088	526	13	surface	surface	NOUN
admet-2088	526	14	chemistry	chemistry	NOUN
admet-2088	526	15	for	for	ADP
admet-2088	526	16	attachment	attachment	NOUN
admet-2088	526	17	of	of	ADP
admet-2088	526	18	ligands	ligand	NOUN
admet-2088	526	19	and	and	CCONJ
admet-2088	526	20	functionalization	functionalization	NOUN
admet-2088	526	21	,	,	PUNCT
admet-2088	526	22	sufficient	sufficient	ADJ
admet-2088	526	23	accumulation	accumulation	NOUN
admet-2088	526	24	at	at	ADP
admet-2088	526	25	the	the	DET
admet-2088	526	26	tumour	tumour	NOUN
admet-2088	526	27	site	site	NOUN
admet-2088	526	28	due	due	ADP
admet-2088	526	29	to	to	ADP
admet-2088	526	30	epr	epr	ADJ
admet-2088	526	31	effect	effect	NOUN
admet-2088	526	32	and	and	CCONJ
admet-2088	526	33	provide	provide	VERB
admet-2088	526	34	safe	safe	ADJ
admet-2088	526	35	,	,	PUNCT
admet-2088	526	36	concurrent	concurrent	ADJ
admet-2088	526	37	or	or	CCONJ
admet-2088	526	38	sequential	sequential	ADJ
admet-2088	526	39	consecutive	consecutive	ADJ
admet-2088	526	40	iv	iv	NUM
admet-2088	526	41	infusion	infusion	NOUN
admet-2088	526	42	in	in	ADP
admet-2088	526	43	diverse	diverse	ADJ
admet-2088	526	44	treatment	treatment	NOUN
admet-2088	526	45	including	include	VERB
admet-2088	526	46	an	an	DET
admet-2088	526	47	aggressive	aggressive	ADJ
admet-2088	526	48	form	form	NOUN
admet-2088	526	49	of	of	ADP
admet-2088	526	50	tumour	tumour	NOUN
admet-2088	526	51	[	[	X
admet-2088	526	52	3	3	NUM
admet-2088	526	53	]	]	PUNCT
admet-2088	526	54	.	.	PUNCT
admet-2088	527	1	despite	despite	SCONJ
admet-2088	527	2	all	all	DET
admet-2088	527	3	positives	positive	NOUN
admet-2088	527	4	,	,	PUNCT
admet-2088	527	5	these	these	DET
admet-2088	527	6	micelles	micelle	NOUN
admet-2088	527	7	show	show	VERB
admet-2088	527	8	burst	burst	ADJ
admet-2088	527	9	drug	drug	NOUN
admet-2088	527	10	release	release	NOUN
admet-2088	527	11	and	and	CCONJ
admet-2088	527	12	lack	lack	NOUN
admet-2088	527	13	of	of	ADP
admet-2088	527	14	targeting	target	VERB
admet-2088	527	15	ability	ability	NOUN
admet-2088	527	16	.	.	PUNCT
admet-2088	528	1	a	a	DET
admet-2088	528	2	stimuli	stimuli	VERB
admet-2088	528	3	-	-	PUNCT
admet-2088	528	4	responsive	responsive	ADJ
admet-2088	528	5	polymeric	polymeric	ADJ
admet-2088	528	6	micelle	micelle	NOUN
admet-2088	528	7	structure	structure	NOUN
admet-2088	528	8	was	be	AUX
admet-2088	528	9	developed	develop	VERB
admet-2088	528	10	to	to	PART
admet-2088	528	11	circumvent	circumvent	VERB
admet-2088	528	12	the	the	DET
admet-2088	528	13	issue	issue	NOUN
admet-2088	528	14	of	of	ADP
admet-2088	528	15	burst	burst	ADJ
admet-2088	528	16	release	release	NOUN
admet-2088	528	17	of	of	ADP
admet-2088	528	18	active	active	ADJ
admet-2088	528	19	drugs	drug	NOUN
admet-2088	528	20	[	[	X
admet-2088	528	21	72	72	NUM
admet-2088	528	22	]	]	PUNCT
admet-2088	528	23	.	.	PUNCT
admet-2088	529	1	on	on	ADP
admet-2088	529	2	the	the	DET
admet-2088	529	3	other	other	ADJ
admet-2088	529	4	hand	hand	NOUN
admet-2088	529	5	,	,	PUNCT
admet-2088	529	6	to	to	PART
admet-2088	529	7	enhance	enhance	VERB
admet-2088	529	8	the	the	DET
admet-2088	529	9	target	target	NOUN
admet-2088	529	10	specificity	specificity	NOUN
admet-2088	529	11	and	and	CCONJ
admet-2088	529	12	binding	bind	VERB
admet-2088	529	13	ability	ability	NOUN
admet-2088	529	14	,	,	PUNCT
admet-2088	529	15	the	the	DET
admet-2088	529	16	corona	corona	NOUN
admet-2088	529	17	(	(	PUNCT
admet-2088	529	18	surface	surface	NOUN
admet-2088	529	19	of	of	ADP
admet-2088	529	20	the	the	DET
admet-2088	529	21	micelle	micelle	NOUN
admet-2088	529	22	)	)	PUNCT
admet-2088	529	23	can	can	AUX
admet-2088	529	24	be	be	AUX
admet-2088	529	25	conjugated	conjugate	VERB
admet-2088	529	26	with	with	ADP
admet-2088	529	27	mab	mab	NOUN
admet-2088	529	28	,	,	PUNCT
admet-2088	529	29	folate	folate	NOUN
admet-2088	529	30	monosaccharides	monosaccharide	NOUN
admet-2088	529	31	,	,	PUNCT
admet-2088	529	32	etc	etc	X
admet-2088	529	33	.	.	X
admet-2088	530	1	[	[	X
admet-2088	530	2	191	191	NUM
admet-2088	530	3	]	]	PUNCT
admet-2088	530	4	.	.	PUNCT
admet-2088	531	1	a	a	DET
admet-2088	531	2	novel	novel	ADJ
admet-2088	531	3	smart	smart	ADJ
admet-2088	531	4	and	and	CCONJ
admet-2088	531	5	efficient	efficient	ADJ
admet-2088	531	6	polymeric	polymeric	ADJ
admet-2088	531	7	micelles	micelle	NOUN
admet-2088	531	8	-	-	PUNCT
admet-2088	531	9	based	base	VERB
admet-2088	531	10	nano	nano	NOUN
admet-2088	531	11	-	-	PUNCT
admet-2088	531	12	dds	dds	PROPN
admet-2088	531	13	embracing	embrace	VERB
admet-2088	531	14	a	a	DET
admet-2088	531	15	combinatorial	combinatorial	ADJ
admet-2088	531	16	approach	approach	NOUN
admet-2088	531	17	of	of	ADP
admet-2088	531	18	chemotherapy	chemotherapy	NOUN
admet-2088	531	19	and	and	CCONJ
admet-2088	531	20	pdt	pdt	PROPN
admet-2088	531	21	was	be	AUX
admet-2088	531	22	developed	develop	VERB
admet-2088	531	23	to	to	PART
admet-2088	531	24	target	target	VERB
admet-2088	531	25	multiple	multiple	ADJ
admet-2088	531	26	independent	independent	ADJ
admet-2088	531	27	therapeutic	therapeutic	ADJ
admet-2088	531	28	pathways	pathway	NOUN
admet-2088	531	29	in	in	ADP
admet-2088	531	30	the	the	DET
admet-2088	531	31	treatment	treatment	NOUN
admet-2088	531	32	of	of	ADP
admet-2088	531	33	melanoma	melanoma	NOUN
admet-2088	531	34	.	.	PUNCT
admet-2088	532	1	the	the	DET
admet-2088	532	2	polymeric	polymeric	ADJ
admet-2088	532	3	micelles	micelle	NOUN
admet-2088	532	4	were	be	AUX
admet-2088	532	5	prepared	prepare	VERB
admet-2088	532	6	from	from	ADP
admet-2088	532	7	methoxy	methoxy	ADJ
admet-2088	532	8	poly(ethylene	poly(ethylene	ADJ
admet-2088	532	9	oxide	oxide	NOUN
admet-2088	532	10	)	)	PUNCT
admet-2088	532	11	and	and	CCONJ
admet-2088	532	12	plga	plga	VERB
admet-2088	532	13	block	block	NOUN
admet-2088	532	14	copolymer	copolymer	NOUN
admet-2088	532	15	(	(	PUNCT
admet-2088	532	16	mpeg	mpeg	NOUN
admet-2088	532	17	-	-	PUNCT
admet-2088	532	18	b	b	NOUN
admet-2088	532	19	-	-	PUNCT
admet-2088	532	20	plga	plga	NOUN
admet-2088	532	21	)	)	PUNCT
admet-2088	532	22	loaded	load	VERB
admet-2088	532	23	with	with	ADP
admet-2088	532	24	dox	dox	NOUN
admet-2088	532	25	and	and	CCONJ
admet-2088	532	26	ir-768	ir-768	NOUN
admet-2088	532	27	photosensitizer	photosensitizer	NOUN
admet-2088	532	28	with	with	ADP
admet-2088	532	29	a	a	DET
admet-2088	532	30	hydrodynamic	hydrodynamic	ADJ
admet-2088	532	31	diameter	diameter	NOUN
admet-2088	532	32	of	of	ADP
admet-2088	532	33	around	around	ADV
admet-2088	532	34	25	25	NUM
admet-2088	532	35	nm	nm	ADJ
admet-2088	532	36	and	and	CCONJ
admet-2088	532	37	spherical	spherical	ADJ
admet-2088	532	38	size	size	NOUN
admet-2088	532	39	.	.	PUNCT
admet-2088	533	1	these	these	DET
admet-2088	533	2	micelles	micelle	NOUN
admet-2088	533	3	demonstrated	demonstrate	VERB
admet-2088	533	4	targeted	target	VERB
admet-2088	533	5	delivery	delivery	NOUN
admet-2088	533	6	and	and	CCONJ
admet-2088	533	7	accumulation	accumulation	NOUN
admet-2088	533	8	in	in	ADP
admet-2088	533	9	mitochondria	mitochondria	NOUN
admet-2088	533	10	of	of	ADP
admet-2088	533	11	a375	a375	PROPN
admet-2088	533	12	melanoma	melanoma	NOUN
admet-2088	533	13	cells	cell	NOUN
admet-2088	533	14	through	through	ADP
admet-2088	533	15	the	the	DET
admet-2088	533	16	epr	epr	PROPN
admet-2088	533	17	effect	effect	NOUN
admet-2088	533	18	and	and	CCONJ
admet-2088	533	19	contributed	contribute	VERB
admet-2088	533	20	to	to	ADP
admet-2088	533	21	excellent	excellent	ADJ
admet-2088	533	22	singlet	singlet	ADJ
admet-2088	533	23	oxygen	oxygen	NOUN
admet-2088	533	24	generation	generation	NOUN
admet-2088	533	25	capacity	capacity	NOUN
admet-2088	533	26	for	for	ADP
admet-2088	533	27	pdt	pdt	PROPN
admet-2088	533	28	.	.	PUNCT
admet-2088	534	1	the	the	DET
admet-2088	534	2	combination	combination	NOUN
admet-2088	534	3	approach	approach	NOUN
admet-2088	534	4	reduces	reduce	VERB
admet-2088	534	5	drug	drug	NOUN
admet-2088	534	6	dose	dose	NOUN
admet-2088	534	7	and	and	CCONJ
admet-2088	534	8	minimizes	minimize	VERB
admet-2088	534	9	side	side	NOUN
admet-2088	534	10	effects	effect	NOUN
admet-2088	534	11	towards	towards	ADP
admet-2088	534	12	normal	normal	ADJ
admet-2088	534	13	hacat	hacat	PROPN
admet-2088	534	14	keratinocytes	keratinocyte	NOUN
admet-2088	534	15	and	and	CCONJ
admet-2088	534	16	triggers	trigger	VERB
admet-2088	534	17	synergistic	synergistic	ADJ
admet-2088	534	18	anticancer	anticancer	NOUN
admet-2088	534	19	effects	effect	NOUN
admet-2088	534	20	in	in	ADP
admet-2088	534	21	melanoma	melanoma	NOUN
admet-2088	534	22	cells	cell	NOUN
admet-2088	534	23	[	[	X
admet-2088	534	24	192	192	NUM
admet-2088	534	25	]	]	PUNCT
admet-2088	534	26	.	.	PUNCT
admet-2088	535	1	nanogels	nanogel	NOUN
admet-2088	535	2	hydrogels	hydrogel	NOUN
admet-2088	535	3	are	be	AUX
admet-2088	535	4	a	a	DET
admet-2088	535	5	three	three	NUM
admet-2088	535	6	-	-	PUNCT
admet-2088	535	7	dimensional	dimensional	ADJ
admet-2088	535	8	cross	cross	ADJ
admet-2088	535	9	-	-	ADJ
admet-2088	535	10	linked	link	VERB
admet-2088	535	11	network	network	NOUN
admet-2088	535	12	of	of	ADP
admet-2088	535	13	polymers	polymer	NOUN
admet-2088	535	14	with	with	ADP
admet-2088	535	15	high	high	ADJ
admet-2088	535	16	water	water	NOUN
admet-2088	535	17	imbibing	imbibing	NOUN
admet-2088	535	18	capacity	capacity	NOUN
admet-2088	535	19	and	and	CCONJ
admet-2088	535	20	swelling	swelling	NOUN
admet-2088	535	21	.	.	PUNCT
admet-2088	536	1	when	when	SCONJ
admet-2088	536	2	hydrogels	hydrogel	NOUN
admet-2088	536	3	are	be	AUX
admet-2088	536	4	formed	form	VERB
admet-2088	536	5	in	in	ADP
admet-2088	536	6	the	the	DET
admet-2088	536	7	nanoscale	nanoscale	NOUN
admet-2088	536	8	range	range	NOUN
admet-2088	536	9	(	(	PUNCT
admet-2088	536	10	100	100	NUM
admet-2088	536	11	-	-	SYM
admet-2088	536	12	200	200	NUM
admet-2088	536	13	nm	nm	NOUN
admet-2088	536	14	)	)	PUNCT
admet-2088	536	15	,	,	PUNCT
admet-2088	536	16	they	they	PRON
admet-2088	536	17	are	be	AUX
admet-2088	536	18	called	call	VERB
admet-2088	536	19	nanogels	nanogel	NOUN
admet-2088	536	20	[	[	X
admet-2088	536	21	193	193	NUM
admet-2088	536	22	]	]	PUNCT
admet-2088	536	23	.	.	PUNCT
admet-2088	537	1	nanogels	nanogel	NOUN
admet-2088	537	2	showed	show	VERB
admet-2088	537	3	several	several	ADJ
admet-2088	537	4	potential	potential	ADJ
admet-2088	537	5	advantages	advantage	NOUN
admet-2088	537	6	over	over	ADP
admet-2088	537	7	other	other	ADJ
admet-2088	537	8	nanocarriers	nanocarrier	NOUN
admet-2088	537	9	,	,	PUNCT
admet-2088	537	10	including	include	VERB
admet-2088	537	11	control	control	NOUN
admet-2088	537	12	over	over	ADP
admet-2088	537	13	size	size	NOUN
admet-2088	537	14	,	,	PUNCT
admet-2088	537	15	large	large	ADJ
admet-2088	537	16	surface	surface	NOUN
admet-2088	537	17	area	area	NOUN
admet-2088	537	18	,	,	PUNCT
admet-2088	537	19	enhanced	enhance	VERB
admet-2088	537	20	stability	stability	NOUN
admet-2088	537	21	due	due	ADP
admet-2088	537	22	to	to	ADP
admet-2088	537	23	enclosed	enclose	VERB
admet-2088	537	24	drugs	drug	NOUN
admet-2088	537	25	,	,	PUNCT
admet-2088	537	26	higher	high	ADJ
admet-2088	537	27	drug	drug	NOUN
admet-2088	537	28	loading	loading	NOUN
admet-2088	537	29	,	,	PUNCT
admet-2088	537	30	controlled	control	VERB
admet-2088	537	31	release	release	NOUN
admet-2088	537	32	of	of	ADP
admet-2088	537	33	active	active	ADJ
admet-2088	537	34	ingredients	ingredient	NOUN
admet-2088	537	35	,	,	PUNCT
admet-2088	537	36	and	and	CCONJ
admet-2088	537	37	enhanced	enhance	VERB
admet-2088	537	38	stimuli	stimulus	NOUN
admet-2088	537	39	-	-	PUNCT
admet-2088	537	40	responsiveness	responsiveness	NOUN
admet-2088	537	41	to	to	ADP
admet-2088	537	42	external	external	ADJ
admet-2088	537	43	stimuli	stimulus	NOUN
admet-2088	537	44	such	such	ADJ
admet-2088	537	45	as	as	ADP
admet-2088	537	46	temperature	temperature	NOUN
admet-2088	537	47	,	,	PUNCT
admet-2088	537	48	ph	ph	ADJ
admet-2088	537	49	,	,	PUNCT
admet-2088	537	50	ions	ion	NOUN
admet-2088	537	51	,	,	PUNCT
admet-2088	537	52	and	and	CCONJ
admet-2088	537	53	enzymes	enzyme	NOUN
admet-2088	537	54	[	[	X
admet-2088	537	55	194,195	194,195	NUM
admet-2088	537	56	]	]	PUNCT
admet-2088	537	57	.	.	PUNCT
admet-2088	538	1	nanogels	nanogel	NOUN
admet-2088	538	2	can	can	AUX
admet-2088	538	3	be	be	AUX
admet-2088	538	4	developed	develop	VERB
admet-2088	538	5	via	via	ADP
admet-2088	538	6	various	various	ADJ
admet-2088	538	7	techniques	technique	NOUN
admet-2088	538	8	such	such	ADJ
admet-2088	538	9	as	as	ADP
admet-2088	538	10	chemical	chemical	NOUN
admet-2088	538	11	cross	cross	ADJ
admet-2088	538	12	-	-	ADJ
admet-2088	538	13	linking	linking	ADJ
admet-2088	538	14	,	,	PUNCT
admet-2088	538	15	polymerization	polymerization	NOUN
admet-2088	538	16	of	of	ADP
admet-2088	538	17	monomer	monomer	NOUN
admet-2088	538	18	units	unit	NOUN
admet-2088	538	19	,	,	PUNCT
admet-2088	538	20	physical	physical	ADJ
admet-2088	538	21	self	self	NOUN
admet-2088	538	22	-	-	PUNCT
admet-2088	538	23	assembly	assembly	NOUN
admet-2088	538	24	and	and	CCONJ
admet-2088	538	25	template	template	NOUN
admet-2088	538	26	-	-	PUNCT
admet-2088	538	27	associated	associate	VERB
admet-2088	538	28	nanofabrication	nanofabrication	NOUN
admet-2088	538	29	[	[	X
admet-2088	538	30	196	196	NUM
admet-2088	538	31	]	]	PUNCT
admet-2088	538	32	.	.	PUNCT
admet-2088	539	1	based	base	VERB
admet-2088	539	2	on	on	ADP
admet-2088	539	3	the	the	DET
admet-2088	539	4	requirements	requirement	NOUN
admet-2088	539	5	,	,	PUNCT
admet-2088	539	6	there	there	PRON
admet-2088	539	7	may	may	AUX
admet-2088	539	8	be	be	AUX
admet-2088	539	9	simple	simple	ADJ
admet-2088	539	10	,	,	PUNCT
admet-2088	539	11	core	core	NOUN
admet-2088	539	12	-	-	PUNCT
admet-2088	539	13	shell	shell	NOUN
admet-2088	539	14	,	,	PUNCT
admet-2088	539	15	multi	multi	ADJ
admet-2088	539	16	-	-	NOUN
admet-2088	539	17	layer	layer	ADJ
admet-2088	539	18	,	,	PUNCT
admet-2088	539	19	hollow	hollow	ADJ
admet-2088	539	20	or	or	CCONJ
admet-2088	539	21	functionalized	functionalized	ADJ
admet-2088	539	22	types	type	NOUN
admet-2088	539	23	of	of	ADP
admet-2088	539	24	nanogels	nanogel	NOUN
admet-2088	539	25	.	.	PUNCT
admet-2088	540	1	glucose	glucose	NOUN
admet-2088	540	2	oxidase	oxidase	NOUN
admet-2088	540	3	(	(	PUNCT
admet-2088	540	4	gox	gox	PROPN
admet-2088	540	5	)	)	PUNCT
admet-2088	540	6	acts	act	VERB
admet-2088	540	7	upon	upon	SCONJ
admet-2088	540	8	glucose	glucose	NOUN
admet-2088	540	9	to	to	PART
admet-2088	540	10	convert	convert	VERB
admet-2088	540	11	it	it	PRON
admet-2088	540	12	to	to	ADP
admet-2088	540	13	gluconic	gluconic	ADJ
admet-2088	540	14	acid	acid	NOUN
admet-2088	540	15	and	and	CCONJ
admet-2088	540	16	h2o2	h2o2	NOUN
admet-2088	540	17	,	,	PUNCT
admet-2088	540	18	which	which	PRON
admet-2088	540	19	has	have	VERB
admet-2088	540	20	synergistic	synergistic	ADJ
admet-2088	540	21	potential	potential	NOUN
admet-2088	540	22	for	for	ADP
admet-2088	540	23	cancer	cancer	NOUN
admet-2088	540	24	-	-	PUNCT
admet-2088	540	25	starving	starve	VERB
admet-2088	540	26	and	and	CCONJ
admet-2088	540	27	oxidation	oxidation	NOUN
admet-2088	540	28	therapy	therapy	NOUN
admet-2088	540	29	.	.	PUNCT
admet-2088	541	1	based	base	VERB
admet-2088	541	2	on	on	ADP
admet-2088	541	3	the	the	DET
admet-2088	541	4	concept	concept	NOUN
admet-2088	541	5	,	,	PUNCT
admet-2088	541	6	zhao	zhao	PROPN
admet-2088	541	7	et	et	PROPN
admet-2088	541	8	al	al	PROPN
admet-2088	541	9	.	.	PUNCT
admet-2088	542	1	[	[	X
admet-2088	542	2	197	197	NUM
admet-2088	542	3	]	]	PUNCT
admet-2088	542	4	developed	develop	VERB
admet-2088	542	5	a	a	DET
admet-2088	542	6	glucoseresponsive	glucoseresponsive	ADJ
admet-2088	542	7	nanomedicine	nanomedicine	NOUN
admet-2088	542	8	,	,	PUNCT
admet-2088	542	9	gox	gox	NOUN
admet-2088	542	10	-	-	PUNCT
admet-2088	542	11	polymer	polymer	NOUN
admet-2088	542	12	nanogels	nanogel	NOUN
admet-2088	542	13	,	,	PUNCT
admet-2088	542	14	comprised	comprise	VERB
admet-2088	542	15	of	of	ADP
admet-2088	542	16	gox	gox	PROPN
admet-2088	542	17	and	and	CCONJ
admet-2088	542	18	polymer	polymer	NOUN
admet-2088	542	19	4	4	NUM
admet-2088	542	20	-	-	PUNCT
admet-2088	542	21	formyl	formyl	NOUN
admet-2088	542	22	-	-	PUNCT
admet-2088	542	23	n-(3-(2-(2-(3	n-(3-(2-(2-(3	NOUN
admet-2088	542	24	-	-	PUNCT
admet-2088	542	25	methacrylamidopropoxy)ethoxy)ethoxy)propyl	methacrylamidopropoxy)ethoxy)ethoxy)propyl	NOUN
admet-2088	542	26	)	)	PUNCT
admet-2088	542	27	benzamide	benzamide	NOUN
admet-2088	542	28	(	(	PUNCT
admet-2088	542	29	fbma	fbma	ADJ
admet-2088	542	30	)	)	PUNCT
admet-2088	542	31	and	and	CCONJ
admet-2088	542	32	oligo	oligo	ADJ
admet-2088	542	33	-	-	PUNCT
admet-2088	542	34	ethylene	ethylene	NOUN
admet-2088	542	35	glycolmonomethyl	glycolmonomethyl	ADJ
admet-2088	542	36	ether	ether	NOUN
admet-2088	542	37	methacrylate	methacrylate	NOUN
admet-2088	542	38	(	(	PUNCT
admet-2088	542	39	oegma	oegma	NOUN
admet-2088	542	40	)	)	PUNCT
admet-2088	542	41	(	(	PUNCT
admet-2088	542	42	poly(fbma	poly(fbma	PROPN
admet-2088	542	43	-	-	PUNCT
admet-2088	542	44	co	co	NOUN
admet-2088	542	45	-	-	NOUN
admet-2088	542	46	oegma	oegma	ADJ
admet-2088	542	47	)	)	PUNCT
admet-2088	542	48	.	.	PUNCT
admet-2088	543	1	this	this	DET
admet-2088	543	2	nanogel	nanogel	NOUN
admet-2088	543	3	showed	show	VERB
admet-2088	543	4	glucose	glucose	NOUN
admet-2088	543	5	-	-	PUNCT
admet-2088	543	6	responsive	responsive	ADJ
admet-2088	543	7	h2o2	h2o2	NOUN
admet-2088	543	8	generating	generate	VERB
admet-2088	543	9	potential	potential	NOUN
admet-2088	543	10	in	in	ADP
admet-2088	543	11	vitro	vitro	X
admet-2088	543	12	,	,	PUNCT
admet-2088	543	13	improved	improve	VERB
admet-2088	543	14	stability	stability	NOUN
admet-2088	543	15	and	and	CCONJ
admet-2088	543	16	significantly	significantly	ADV
admet-2088	543	17	improved	improve	VERB
admet-2088	543	18	tumour	tumour	NOUN
admet-2088	543	19	retention	retention	NOUN
admet-2088	543	20	than	than	ADP
admet-2088	543	21	that	that	PRON
admet-2088	543	22	of	of	ADP
admet-2088	543	23	gox	gox	PROPN
admet-2088	543	24	alone	alone	ADV
admet-2088	543	25	.	.	PUNCT
admet-2088	544	1	in	in	ADP
admet-2088	544	2	addition	addition	NOUN
admet-2088	544	3	,	,	PUNCT
admet-2088	544	4	the	the	DET
admet-2088	544	5	nanogel	nanogel	NOUN
admet-2088	544	6	showed	show	VERB
admet-2088	544	7	high	high	ADJ
admet-2088	544	8	anti	anti	ADJ
admet-2088	544	9	-	-	ADJ
admet-2088	544	10	melanoma	melanoma	ADJ
admet-2088	544	11	efficacy	efficacy	NOUN
admet-2088	544	12	without	without	ADP
admet-2088	544	13	systemic	systemic	ADJ
admet-2088	544	14	toxicity	toxicity	NOUN
admet-2088	544	15	due	due	ADP
admet-2088	544	16	to	to	ADP
admet-2088	544	17	the	the	DET
admet-2088	544	18	confinement	confinement	NOUN
admet-2088	544	19	of	of	ADP
admet-2088	544	20	gox	gox	PROPN
admet-2088	544	21	to	to	ADP
admet-2088	544	22	only	only	ADV
admet-2088	544	23	the	the	DET
admet-2088	544	24	tumour	tumour	NOUN
admet-2088	544	25	region	region	NOUN
admet-2088	544	26	.	.	PUNCT
admet-2088	545	1	an	an	DET
admet-2088	545	2	injectable	injectable	ADJ
admet-2088	545	3	thermosensitive	thermosensitive	NOUN
admet-2088	545	4	nano	nano	NOUN
admet-2088	545	5	-	-	PUNCT
admet-2088	545	6	hydrogel	hydrogel	NOUN
admet-2088	545	7	was	be	AUX
admet-2088	545	8	developed	develop	VERB
admet-2088	545	9	with	with	ADP
admet-2088	545	10	cationized	cationized	ADJ
admet-2088	545	11	agarose	agarose	NOUN
admet-2088	545	12	and	and	CCONJ
admet-2088	545	13	tmpo	tmpo	NOUN
admet-2088	545	14	-	-	PUNCT
admet-2088	545	15	oxidized	oxidize	VERB
admet-2088	545	16	lignocellulose	lignocellulose	NOUN
admet-2088	545	17	at	at	ADP
admet-2088	545	18	different	different	ADJ
admet-2088	545	19	proportions	proportion	NOUN
admet-2088	545	20	and	and	CCONJ
admet-2088	545	21	loaded	load	VERB
admet-2088	545	22	with	with	ADP
admet-2088	545	23	pp	pp	ADV
admet-2088	545	24	-	-	PUNCT
admet-2088	545	25	nps	nps	PROPN
admet-2088	545	26	containing	contain	VERB
admet-2088	545	27	deferasirox	deferasirox	NOUN
admet-2088	545	28	,	,	PUNCT
admet-2088	545	29	an	an	DET
admet-2088	545	30	inhibitor	inhibitor	NOUN
admet-2088	545	31	of	of	ADP
admet-2088	545	32	iron	iron	NOUN
admet-2088	545	33	metabolism	metabolism	NOUN
admet-2088	545	34	in	in	ADP
admet-2088	545	35	the	the	DET
admet-2088	545	36	cancer	cancer	NOUN
admet-2088	545	37	cells	cell	NOUN
admet-2088	545	38	by	by	ADP
admet-2088	545	39	chelating	chelate	VERB
admet-2088	545	40	action	action	NOUN
admet-2088	545	41	.	.	PUNCT
admet-2088	546	1	the	the	DET
admet-2088	546	2	nano	nano	NOUN
admet-2088	546	3	-	-	PUNCT
admet-2088	546	4	hydrogel	hydrogel	NOUN
admet-2088	546	5	containing	contain	VERB
admet-2088	546	6	2	2	NUM
admet-2088	546	7	%	%	NOUN
admet-2088	546	8	lignocellulose	lignocellulose	NOUN
admet-2088	546	9	and	and	CCONJ
admet-2088	546	10	0.5	0.5	NUM
admet-2088	546	11	%	%	NOUN
admet-2088	546	12	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	546	13	m.	m.	NOUN
admet-2088	547	1	kulkarni	kulkarni	PROPN
admet-2088	547	2	et	et	PROPN
admet-2088	547	3	al	al	PROPN
admet-2088	547	4	.	.	PROPN
admet-2088	547	5	admet	admet	PROPN
admet-2088	547	6	&	&	CCONJ
admet-2088	547	7	dmpk	dmpk	PROPN
admet-2088	547	8	12(1	12(1	PROPN
admet-2088	547	9	)	)	PUNCT
admet-2088	547	10	(	(	PUNCT
admet-2088	547	11	2024	2024	NUM
admet-2088	547	12	)	)	PUNCT
admet-2088	547	13	107	107	NUM
admet-2088	547	14	-	-	SYM
admet-2088	547	15	150	150	NUM
admet-2088	547	16	128	128	NUM
admet-2088	547	17	agarose	agarose	NOUN
admet-2088	547	18	demonstrated	demonstrate	VERB
admet-2088	547	19	the	the	DET
admet-2088	547	20	shortest	short	ADJ
admet-2088	547	21	gelation	gelation	NOUN
admet-2088	547	22	time	time	NOUN
admet-2088	547	23	(	(	PUNCT
admet-2088	547	24	10.3	10.3	NUM
admet-2088	547	25	min	min	NOUN
admet-2088	547	26	)	)	PUNCT
admet-2088	547	27	with	with	ADP
admet-2088	547	28	the	the	DET
admet-2088	547	29	highest	high	ADJ
admet-2088	547	30	mechanical	mechanical	ADJ
admet-2088	547	31	strength	strength	NOUN
admet-2088	547	32	.	.	PUNCT
admet-2088	548	1	this	this	DET
admet-2088	548	2	nanogel	nanogel	NOUN
admet-2088	548	3	demonstrated	demonstrate	VERB
admet-2088	548	4	dose	dose	NOUN
admet-2088	548	5	-	-	PUNCT
admet-2088	548	6	dependent	dependent	ADJ
admet-2088	548	7	cytotoxicity	cytotoxicity	NOUN
admet-2088	548	8	and	and	CCONJ
admet-2088	548	9	this	this	DET
admet-2088	548	10	efficacy	efficacy	NOUN
admet-2088	548	11	was	be	AUX
admet-2088	548	12	further	far	ADV
admet-2088	548	13	increased	increase	VERB
admet-2088	548	14	by	by	ADP
admet-2088	548	15	irradiation	irradiation	NOUN
admet-2088	548	16	with	with	ADP
admet-2088	548	17	laser	laser	NOUN
admet-2088	548	18	light	light	NOUN
admet-2088	548	19	[	[	X
admet-2088	548	20	198	198	NUM
admet-2088	548	21	]	]	PUNCT
admet-2088	548	22	.	.	PUNCT
admet-2088	549	1	lipid	lipid	NOUN
admet-2088	549	2	-	-	PUNCT
admet-2088	549	3	based	base	VERB
admet-2088	549	4	nms	nms	PROPN
admet-2088	549	5	bangham	bangham	PROPN
admet-2088	549	6	et	et	PROPN
admet-2088	549	7	al	al	PROPN
admet-2088	549	8	.	.	PUNCT
admet-2088	550	1	[	[	X
admet-2088	550	2	72	72	NUM
admet-2088	550	3	]	]	X
admet-2088	550	4	first	first	ADV
admet-2088	550	5	introduced	introduce	VERB
admet-2088	550	6	lipid	lipid	NOUN
admet-2088	550	7	-	-	PUNCT
admet-2088	550	8	based	base	VERB
admet-2088	550	9	nms	nms	NOUN
admet-2088	550	10	for	for	ADP
admet-2088	550	11	drug	drug	NOUN
admet-2088	550	12	delivery	delivery	NOUN
admet-2088	550	13	in	in	ADP
admet-2088	550	14	1965	1965	NUM
admet-2088	550	15	,	,	PUNCT
admet-2088	550	16	initially	initially	ADV
admet-2088	550	17	called	call	VERB
admet-2088	550	18	“	"	PUNCT
admet-2088	550	19	bangosomes	bangosome	NOUN
admet-2088	550	20	”	"	PUNCT
admet-2088	550	21	and	and	CCONJ
admet-2088	550	22	then	then	ADV
admet-2088	550	23	liposomes	liposome	NOUN
admet-2088	550	24	.	.	PUNCT
admet-2088	551	1	lipid	lipid	NOUN
admet-2088	551	2	-	-	PUNCT
admet-2088	551	3	based	base	VERB
admet-2088	551	4	nps	nps	PROPN
admet-2088	551	5	are	be	AUX
admet-2088	551	6	the	the	DET
admet-2088	551	7	most	most	ADV
admet-2088	551	8	popular	popular	ADJ
admet-2088	551	9	drug	drug	NOUN
admet-2088	551	10	organic	organic	ADJ
admet-2088	551	11	nanocarriers	nanocarrier	NOUN
admet-2088	551	12	for	for	ADP
admet-2088	551	13	cancer	cancer	NOUN
admet-2088	551	14	treatment	treatment	NOUN
admet-2088	551	15	due	due	ADP
admet-2088	551	16	to	to	ADP
admet-2088	551	17	their	their	PRON
admet-2088	551	18	biodegradability	biodegradability	NOUN
admet-2088	551	19	,	,	PUNCT
admet-2088	551	20	biocompatibility	biocompatibility	NOUN
admet-2088	551	21	,	,	PUNCT
admet-2088	551	22	simple	simple	ADJ
admet-2088	551	23	synthesis	synthesis	NOUN
admet-2088	551	24	techniques	technique	NOUN
admet-2088	551	25	and	and	CCONJ
admet-2088	551	26	higher	high	ADJ
admet-2088	551	27	drugloading	drugloade	VERB
admet-2088	551	28	efficiency	efficiency	NOUN
admet-2088	551	29	[	[	X
admet-2088	551	30	199,200	199,200	NUM
admet-2088	551	31	]	]	PUNCT
admet-2088	551	32	.	.	PUNCT
admet-2088	552	1	liposomes	liposome	NOUN
admet-2088	552	2	liposomes	liposome	NOUN
admet-2088	552	3	are	be	AUX
admet-2088	552	4	spherical	spherical	ADJ
admet-2088	552	5	vesicles	vesicle	NOUN
admet-2088	552	6	comprised	comprise	VERB
admet-2088	552	7	of	of	ADP
admet-2088	552	8	an	an	DET
admet-2088	552	9	aqueous	aqueous	ADJ
admet-2088	552	10	core	core	NOUN
admet-2088	552	11	enclosed	enclose	VERB
admet-2088	552	12	by	by	ADP
admet-2088	552	13	one	one	NUM
admet-2088	552	14	or	or	CCONJ
admet-2088	552	15	more	more	ADJ
admet-2088	552	16	lipid	lipid	ADJ
admet-2088	552	17	bilayers	bilayer	NOUN
admet-2088	552	18	.	.	PUNCT
admet-2088	553	1	this	this	PRON
admet-2088	553	2	enables	enable	VERB
admet-2088	553	3	the	the	DET
admet-2088	553	4	loading	loading	NOUN
admet-2088	553	5	of	of	ADP
admet-2088	553	6	hydrophilic	hydrophilic	ADJ
admet-2088	553	7	drugs	drug	NOUN
admet-2088	553	8	at	at	ADP
admet-2088	553	9	the	the	DET
admet-2088	553	10	aqueous	aqueous	ADJ
admet-2088	553	11	core	core	NOUN
admet-2088	553	12	and	and	CCONJ
admet-2088	553	13	lipophilic	lipophilic	ADJ
admet-2088	553	14	drugs	drug	NOUN
admet-2088	553	15	in	in	ADP
admet-2088	553	16	the	the	DET
admet-2088	553	17	lipid	lipid	ADJ
admet-2088	553	18	bilayers	bilayer	NOUN
admet-2088	553	19	[	[	X
admet-2088	553	20	201	201	NUM
admet-2088	553	21	]	]	PUNCT
admet-2088	553	22	.	.	PUNCT
admet-2088	554	1	they	they	PRON
admet-2088	554	2	are	be	AUX
admet-2088	554	3	mostly	mostly	ADV
admet-2088	554	4	synthesized	synthesize	VERB
admet-2088	554	5	from	from	ADP
admet-2088	554	6	one	one	NUM
admet-2088	554	7	or	or	CCONJ
admet-2088	554	8	more	more	ADJ
admet-2088	554	9	phospholipids	phospholipid	NOUN
admet-2088	554	10	such	such	ADJ
admet-2088	554	11	as	as	ADP
admet-2088	554	12	phosphatidylcholine	phosphatidylcholine	NOUN
admet-2088	554	13	(	(	PUNCT
admet-2088	554	14	pc	pc	NOUN
admet-2088	554	15	)	)	PUNCT
admet-2088	554	16	,	,	PUNCT
admet-2088	554	17	phosphatidylethanolamine	phosphatidylethanolamine	PROPN
admet-2088	554	18	(	(	PUNCT
admet-2088	554	19	pe	pe	NOUN
admet-2088	554	20	)	)	PUNCT
admet-2088	554	21	,	,	PUNCT
admet-2088	554	22	phosphatidylglycerol	phosphatidylglycerol	NOUN
admet-2088	554	23	,	,	PUNCT
admet-2088	554	24	etc	etc	X
admet-2088	554	25	.	.	X
admet-2088	554	26	,	,	PUNCT
admet-2088	554	27	and	and	CCONJ
admet-2088	554	28	cholesterol	cholesterol	NOUN
admet-2088	554	29	as	as	ADP
admet-2088	554	30	a	a	DET
admet-2088	554	31	stabilizer	stabilizer	NOUN
admet-2088	554	32	for	for	ADP
admet-2088	554	33	the	the	DET
admet-2088	554	34	bilipid	bilipid	ADJ
admet-2088	554	35	layer	layer	NOUN
admet-2088	555	1	[	[	X
admet-2088	555	2	202	202	NUM
admet-2088	555	3	]	]	PUNCT
admet-2088	555	4	.	.	PUNCT
admet-2088	556	1	liposomes	liposome	NOUN
admet-2088	556	2	as	as	SCONJ
admet-2088	556	3	dds	dds	PROPN
admet-2088	556	4	have	have	VERB
admet-2088	556	5	many	many	ADJ
admet-2088	556	6	advantages	advantage	NOUN
admet-2088	556	7	,	,	PUNCT
admet-2088	556	8	such	such	ADJ
admet-2088	556	9	as	as	ADP
admet-2088	556	10	nanoscale	nanoscale	NOUN
admet-2088	556	11	size	size	NOUN
admet-2088	556	12	,	,	PUNCT
admet-2088	556	13	amphiphilic	amphiphilic	ADJ
admet-2088	556	14	nature	nature	NOUN
admet-2088	556	15	,	,	PUNCT
admet-2088	556	16	biocompatibility	biocompatibility	NOUN
admet-2088	556	17	,	,	PUNCT
admet-2088	556	18	ease	ease	NOUN
admet-2088	556	19	of	of	ADP
admet-2088	556	20	preparation	preparation	NOUN
admet-2088	556	21	through	through	ADP
admet-2088	556	22	numerous	numerous	ADJ
admet-2088	556	23	methods	method	NOUN
admet-2088	556	24	,	,	PUNCT
admet-2088	556	25	and	and	CCONJ
admet-2088	556	26	exceptional	exceptional	ADJ
admet-2088	556	27	endocytosis	endocytosis	NOUN
admet-2088	556	28	and	and	CCONJ
admet-2088	556	29	diffusion	diffusion	NOUN
admet-2088	556	30	,	,	PUNCT
admet-2088	556	31	leading	lead	VERB
admet-2088	556	32	to	to	ADP
admet-2088	556	33	their	their	PRON
admet-2088	556	34	interactions	interaction	NOUN
admet-2088	556	35	and	and	CCONJ
admet-2088	556	36	penetration	penetration	NOUN
admet-2088	556	37	across	across	ADP
admet-2088	556	38	biological	biological	ADJ
admet-2088	556	39	membranes	membrane	NOUN
admet-2088	556	40	[	[	X
admet-2088	556	41	203,204	203,204	NUM
admet-2088	556	42	]	]	PUNCT
admet-2088	556	43	.	.	PUNCT
admet-2088	557	1	however	however	ADV
admet-2088	557	2	,	,	PUNCT
admet-2088	557	3	the	the	DET
admet-2088	557	4	higher	high	ADJ
admet-2088	557	5	production	production	NOUN
admet-2088	557	6	cost	cost	NOUN
admet-2088	557	7	,	,	PUNCT
admet-2088	557	8	short	short	ADJ
admet-2088	557	9	half	half	ADJ
admet-2088	557	10	-	-	PUNCT
admet-2088	557	11	life	life	NOUN
admet-2088	557	12	,	,	PUNCT
admet-2088	557	13	and	and	CCONJ
admet-2088	557	14	stability	stability	NOUN
admet-2088	557	15	issues	issue	NOUN
admet-2088	557	16	like	like	ADP
admet-2088	557	17	leakage	leakage	NOUN
admet-2088	557	18	leading	lead	VERB
admet-2088	557	19	to	to	ADP
admet-2088	557	20	premature	premature	ADJ
admet-2088	557	21	drug	drug	NOUN
admet-2088	557	22	release	release	NOUN
admet-2088	557	23	and	and	CCONJ
admet-2088	557	24	opsonization	opsonization	NOUN
admet-2088	557	25	after	after	ADP
admet-2088	557	26	administration	administration	NOUN
admet-2088	557	27	through	through	ADP
admet-2088	557	28	the	the	DET
admet-2088	557	29	iv	iv	NUM
admet-2088	557	30	route	route	NOUN
admet-2088	557	31	are	be	AUX
admet-2088	557	32	the	the	DET
admet-2088	557	33	major	major	ADJ
admet-2088	557	34	issues	issue	NOUN
admet-2088	557	35	with	with	ADP
admet-2088	557	36	liposomes	liposome	NOUN
admet-2088	557	37	[	[	X
admet-2088	557	38	205	205	NUM
admet-2088	557	39	]	]	PUNCT
admet-2088	557	40	.	.	PUNCT
admet-2088	558	1	pegylated	pegylate	VERB
admet-2088	558	2	liposomes	liposome	NOUN
admet-2088	558	3	(	(	PUNCT
admet-2088	558	4	peg	peg	NOUN
admet-2088	558	5	molecule	molecule	NOUN
admet-2088	558	6	coated	coat	VERB
admet-2088	558	7	liposomes	liposome	NOUN
admet-2088	558	8	)	)	PUNCT
admet-2088	558	9	can	can	AUX
admet-2088	558	10	circumvent	circumvent	VERB
admet-2088	558	11	the	the	DET
admet-2088	558	12	problem	problem	NOUN
admet-2088	558	13	of	of	ADP
admet-2088	558	14	opsonization	opsonization	NOUN
admet-2088	558	15	,	,	PUNCT
admet-2088	558	16	resulting	result	VERB
admet-2088	558	17	in	in	ADP
admet-2088	558	18	long	long	ADJ
admet-2088	558	19	circulation	circulation	NOUN
admet-2088	558	20	time	time	NOUN
admet-2088	558	21	of	of	ADP
admet-2088	558	22	liposomes	liposome	NOUN
admet-2088	558	23	.	.	PUNCT
admet-2088	559	1	similarly	similarly	ADV
admet-2088	559	2	,	,	PUNCT
admet-2088	559	3	the	the	DET
admet-2088	559	4	incorporation	incorporation	NOUN
admet-2088	559	5	of	of	ADP
admet-2088	559	6	cholesterol	cholesterol	NOUN
admet-2088	559	7	prevents	prevent	VERB
admet-2088	559	8	the	the	DET
admet-2088	559	9	leakage	leakage	NOUN
admet-2088	559	10	problem	problem	NOUN
admet-2088	559	11	by	by	ADP
admet-2088	559	12	increasing	increase	VERB
admet-2088	559	13	the	the	DET
admet-2088	559	14	phase	phase	NOUN
admet-2088	559	15	transition	transition	NOUN
admet-2088	559	16	temperature	temperature	NOUN
admet-2088	559	17	of	of	ADP
admet-2088	559	18	phospholipids	phospholipid	NOUN
admet-2088	559	19	[	[	X
admet-2088	559	20	206	206	NUM
admet-2088	559	21	]	]	PUNCT
admet-2088	559	22	.	.	PUNCT
admet-2088	560	1	other	other	ADJ
admet-2088	560	2	types	type	NOUN
admet-2088	560	3	of	of	ADP
admet-2088	560	4	liposomes	liposome	NOUN
admet-2088	560	5	developed	develop	VERB
admet-2088	560	6	are	be	AUX
admet-2088	560	7	cationic	cationic	ADJ
admet-2088	560	8	liposomes	liposome	NOUN
admet-2088	560	9	,	,	PUNCT
admet-2088	560	10	ph	ph	ADJ
admet-2088	560	11	-	-	ADJ
admet-2088	560	12	sensitive	sensitive	ADJ
admet-2088	560	13	and	and	CCONJ
admet-2088	560	14	immune	immune	ADJ
admet-2088	560	15	liposomes	liposome	NOUN
admet-2088	560	16	,	,	PUNCT
admet-2088	560	17	which	which	PRON
admet-2088	560	18	have	have	VERB
admet-2088	560	19	great	great	ADJ
admet-2088	560	20	importance	importance	NOUN
admet-2088	560	21	in	in	ADP
admet-2088	560	22	targeted	target	VERB
admet-2088	560	23	drug	drug	NOUN
admet-2088	560	24	delivery	delivery	NOUN
admet-2088	560	25	.	.	PUNCT
admet-2088	561	1	to	to	PART
admet-2088	561	2	improve	improve	VERB
admet-2088	561	3	upon	upon	SCONJ
admet-2088	561	4	the	the	DET
admet-2088	561	5	limitation	limitation	NOUN
admet-2088	561	6	of	of	ADP
admet-2088	561	7	cancer	cancer	NOUN
admet-2088	561	8	vaccine	vaccine	NOUN
admet-2088	561	9	efficacy	efficacy	NOUN
admet-2088	561	10	,	,	PUNCT
admet-2088	561	11	a	a	DET
admet-2088	561	12	combinatorial	combinatorial	ADJ
admet-2088	561	13	approach	approach	NOUN
admet-2088	561	14	with	with	ADP
admet-2088	561	15	liposomal	liposomal	PROPN
admet-2088	561	16	celecoxib	celecoxib	PROPN
admet-2088	561	17	and	and	CCONJ
admet-2088	561	18	ex	ex	PRON
admet-2088	561	19	vivo	vivo	NOUN
admet-2088	561	20	generated	generate	VERB
admet-2088	561	21	dendritic	dendritic	ADJ
admet-2088	561	22	cell	cell	NOUN
admet-2088	561	23	vaccines	vaccine	NOUN
admet-2088	561	24	pulsed	pulse	VERB
admet-2088	561	25	with	with	ADP
admet-2088	561	26	gp100	gp100	PROPN
admet-2088	561	27	peptide	peptide	NOUN
admet-2088	561	28	was	be	AUX
admet-2088	561	29	undertaken	undertake	VERB
admet-2088	561	30	for	for	ADP
admet-2088	561	31	the	the	DET
admet-2088	561	32	prophylactic	prophylactic	ADJ
admet-2088	561	33	and	and	CCONJ
admet-2088	561	34	therapeutic	therapeutic	ADJ
admet-2088	561	35	anti	anti	ADJ
admet-2088	561	36	-	-	ADJ
admet-2088	561	37	tumour	tumour	ADJ
admet-2088	561	38	immune	immune	ADJ
admet-2088	561	39	response	response	NOUN
admet-2088	561	40	.	.	PUNCT
admet-2088	562	1	the	the	DET
admet-2088	562	2	iv	iv	NUM
admet-2088	562	3	administration	administration	NOUN
admet-2088	562	4	of	of	ADP
admet-2088	562	5	liposomal	liposomal	PROPN
admet-2088	562	6	celecoxib	celecoxib	NOUN
admet-2088	562	7	in	in	ADP
admet-2088	562	8	a	a	DET
admet-2088	562	9	mouse	mouse	NOUN
admet-2088	562	10	model	model	NOUN
admet-2088	562	11	of	of	ADP
admet-2088	562	12	melanoma	melanoma	NOUN
admet-2088	562	13	showed	show	VERB
admet-2088	562	14	the	the	DET
admet-2088	562	15	normalization	normalization	NOUN
admet-2088	562	16	of	of	ADP
admet-2088	562	17	the	the	DET
admet-2088	562	18	tumour	tumour	NOUN
admet-2088	562	19	microenvironment	microenvironment	NOUN
admet-2088	562	20	by	by	ADP
admet-2088	562	21	inhibiting	inhibit	VERB
admet-2088	562	22	the	the	DET
admet-2088	562	23	proliferation	proliferation	NOUN
admet-2088	562	24	of	of	ADP
admet-2088	562	25	regulatory	regulatory	ADJ
admet-2088	562	26	t	t	NOUN
admet-2088	562	27	cells	cell	NOUN
admet-2088	562	28	and	and	CCONJ
admet-2088	562	29	il-10	il-10	DET
admet-2088	562	30	production	production	NOUN
admet-2088	562	31	.	.	PUNCT
admet-2088	563	1	the	the	DET
admet-2088	563	2	combination	combination	NOUN
admet-2088	563	3	of	of	ADP
admet-2088	563	4	liposomal	liposomal	ADJ
admet-2088	563	5	celecoxib	celecoxib	PROPN
admet-2088	563	6	and	and	CCONJ
admet-2088	563	7	dendritic	dendritic	ADJ
admet-2088	563	8	vaccine	vaccine	NOUN
admet-2088	563	9	pulsed	pulse	VERB
admet-2088	563	10	with	with	ADP
admet-2088	563	11	gp100	gp100	PROPN
admet-2088	563	12	peptide	peptide	NOUN
admet-2088	563	13	significantly	significantly	ADV
admet-2088	563	14	improved	improve	VERB
admet-2088	563	15	cd4	cd4	PROPN
admet-2088	563	16	+	+	PROPN
admet-2088	563	17	and	and	CCONJ
admet-2088	563	18	cd8	cd8	PROPN
admet-2088	563	19	+	+	PROPN
admet-2088	563	20	t	t	PROPN
admet-2088	563	21	cells	cell	NOUN
admet-2088	563	22	infiltration	infiltration	NOUN
admet-2088	563	23	and	and	CCONJ
admet-2088	563	24	secretion	secretion	NOUN
admet-2088	563	25	of	of	ADP
admet-2088	563	26	ifn-.	ifn-.	PROPN
admet-2088	563	27	thus	thus	ADV
admet-2088	563	28	,	,	PUNCT
admet-2088	563	29	the	the	DET
admet-2088	563	30	combinatorial	combinatorial	ADJ
admet-2088	563	31	strategy	strategy	NOUN
admet-2088	563	32	successfully	successfully	ADV
admet-2088	563	33	demonstrated	demonstrate	VERB
admet-2088	563	34	tumour	tumour	NOUN
admet-2088	563	35	growth	growth	NOUN
admet-2088	563	36	inhibition	inhibition	NOUN
admet-2088	563	37	and	and	CCONJ
admet-2088	563	38	overall	overall	ADJ
admet-2088	563	39	survival	survival	NOUN
admet-2088	564	1	[	[	X
admet-2088	564	2	207	207	NUM
admet-2088	564	3	]	]	PUNCT
admet-2088	564	4	.	.	PUNCT
admet-2088	565	1	in	in	ADP
admet-2088	565	2	one	one	NUM
admet-2088	565	3	study	study	NOUN
admet-2088	565	4	,	,	PUNCT
admet-2088	565	5	chitosan	chitosan	NOUN
admet-2088	565	6	-	-	PUNCT
admet-2088	565	7	coated	coat	VERB
admet-2088	565	8	liposomes	liposome	NOUN
admet-2088	565	9	were	be	AUX
admet-2088	565	10	developed	develop	VERB
admet-2088	565	11	with	with	ADP
admet-2088	565	12	the	the	DET
admet-2088	565	13	intention	intention	NOUN
admet-2088	565	14	to	to	PART
admet-2088	565	15	stabilize	stabilize	VERB
admet-2088	565	16	and	and	CCONJ
admet-2088	565	17	increase	increase	VERB
admet-2088	565	18	the	the	DET
admet-2088	565	19	skin	skin	NOUN
admet-2088	565	20	permeation	permeation	NOUN
admet-2088	565	21	potential	potential	NOUN
admet-2088	565	22	of	of	ADP
admet-2088	565	23	indocyanine	indocyanine	NOUN
admet-2088	565	24	green	green	NOUN
admet-2088	565	25	for	for	ADP
admet-2088	565	26	pdt	pdt	NOUN
admet-2088	565	27	against	against	ADP
admet-2088	565	28	melanoma	melanoma	NOUN
admet-2088	565	29	.	.	PUNCT
admet-2088	566	1	no	no	ADV
admet-2088	566	2	doubt	doubt	ADV
admet-2088	566	3	,	,	PUNCT
admet-2088	566	4	the	the	DET
admet-2088	566	5	prepared	prepare	VERB
admet-2088	566	6	liposomes	liposome	NOUN
admet-2088	566	7	protected	protect	VERB
admet-2088	566	8	indocyanine	indocyanine	NOUN
admet-2088	566	9	green	green	ADJ
admet-2088	566	10	from	from	ADP
admet-2088	566	11	degradation	degradation	NOUN
admet-2088	566	12	as	as	SCONJ
admet-2088	566	13	compared	compare	VERB
admet-2088	566	14	to	to	ADP
admet-2088	566	15	uncoated	uncoated	ADJ
admet-2088	566	16	liposomes	liposome	NOUN
admet-2088	566	17	.	.	PUNCT
admet-2088	567	1	the	the	DET
admet-2088	567	2	skin	skin	NOUN
admet-2088	567	3	permeation	permeation	NOUN
admet-2088	567	4	of	of	ADP
admet-2088	567	5	indocyanine	indocyanine	ADJ
admet-2088	567	6	green	green	PROPN
admet-2088	567	7	was	be	AUX
admet-2088	567	8	found	find	VERB
admet-2088	567	9	to	to	PART
admet-2088	567	10	be	be	AUX
admet-2088	567	11	significantly	significantly	ADV
admet-2088	567	12	increased	increase	VERB
admet-2088	567	13	by	by	ADP
admet-2088	567	14	chitosan	chitosan	NOUN
admet-2088	567	15	-	-	PUNCT
admet-2088	567	16	coated	coat	VERB
admet-2088	567	17	liposomes	liposome	NOUN
admet-2088	567	18	.	.	PUNCT
admet-2088	568	1	in	in	ADP
admet-2088	568	2	addition	addition	NOUN
admet-2088	568	3	,	,	PUNCT
admet-2088	568	4	the	the	DET
admet-2088	568	5	cellular	cellular	ADJ
admet-2088	568	6	uptake	uptake	NOUN
admet-2088	568	7	and	and	CCONJ
admet-2088	568	8	photocytotoxicity	photocytotoxicity	NOUN
admet-2088	568	9	of	of	ADP
admet-2088	568	10	indocyanine	indocyanine	NOUN
admet-2088	568	11	green	green	ADJ
admet-2088	568	12	in	in	ADP
admet-2088	568	13	the	the	DET
admet-2088	568	14	melanoma	melanoma	NOUN
admet-2088	568	15	cell	cell	NOUN
admet-2088	568	16	line	line	NOUN
admet-2088	568	17	(	(	PUNCT
admet-2088	568	18	b16	b16	PROPN
admet-2088	568	19	-	-	PUNCT
admet-2088	568	20	f10	f10	NOUN
admet-2088	568	21	)	)	PUNCT
admet-2088	568	22	were	be	AUX
admet-2088	568	23	exceptionally	exceptionally	ADV
admet-2088	568	24	high	high	ADJ
admet-2088	568	25	for	for	ADP
admet-2088	568	26	the	the	DET
admet-2088	568	27	coated	coat	VERB
admet-2088	568	28	liposomes	liposome	NOUN
admet-2088	568	29	in	in	ADP
admet-2088	568	30	a	a	DET
admet-2088	568	31	chitosan	chitosan	NOUN
admet-2088	568	32	-	-	PUNCT
admet-2088	568	33	dependent	dependent	ADJ
admet-2088	568	34	manner	manner	NOUN
admet-2088	569	1	[	[	X
admet-2088	569	2	208	208	NUM
admet-2088	569	3	]	]	PUNCT
admet-2088	569	4	.	.	PUNCT
admet-2088	570	1	in	in	ADP
admet-2088	570	2	another	another	DET
admet-2088	570	3	study	study	NOUN
admet-2088	570	4	,	,	PUNCT
admet-2088	570	5	dacarbazine	dacarbazine	NOUN
admet-2088	570	6	and	and	CCONJ
admet-2088	570	7	eugenol	eugenol	NOUN
admet-2088	570	8	-	-	PUNCT
admet-2088	570	9	loaded	load	VERB
admet-2088	570	10	liposomes	liposome	NOUN
admet-2088	570	11	were	be	AUX
admet-2088	570	12	surface	surface	NOUN
admet-2088	570	13	-	-	PUNCT
admet-2088	570	14	functionalized	functionalize	VERB
admet-2088	570	15	with	with	ADP
admet-2088	570	16	ha	ha	INTJ
admet-2088	570	17	for	for	ADP
admet-2088	570	18	the	the	DET
admet-2088	570	19	treatment	treatment	NOUN
admet-2088	570	20	of	of	ADP
admet-2088	570	21	aggressive	aggressive	ADJ
admet-2088	570	22	metastatic	metastatic	ADJ
admet-2088	570	23	melanoma	melanoma	NOUN
admet-2088	570	24	.	.	PUNCT
admet-2088	571	1	the	the	DET
admet-2088	571	2	obtained	obtain	VERB
admet-2088	571	3	coated	coated	ADJ
admet-2088	571	4	liposomes	liposome	NOUN
admet-2088	571	5	showed	show	VERB
admet-2088	571	6	higher	high	ADJ
admet-2088	571	7	cytotoxicity	cytotoxicity	NOUN
admet-2088	571	8	of	of	ADP
admet-2088	571	9	95.08	95.08	NUM
admet-2088	571	10	%	%	NOUN
admet-2088	571	11	at	at	ADP
admet-2088	571	12	a	a	DET
admet-2088	571	13	dacarbazine	dacarbazine	NOUN
admet-2088	571	14	concentration	concentration	NOUN
admet-2088	571	15	of	of	ADP
admet-2088	571	16	0.5	0.5	NUM
admet-2088	571	17	µg	µg	ADV
admet-2088	571	18	ml-1	ml-1	PRON
admet-2088	571	19	compared	compare	VERB
admet-2088	571	20	to	to	ADP
admet-2088	571	21	only	only	ADV
admet-2088	571	22	10.20	10.20	NUM
admet-2088	571	23	%	%	NOUN
admet-2088	571	24	cytotoxicity	cytotoxicity	NOUN
admet-2088	571	25	shown	show	VERB
admet-2088	571	26	by	by	ADP
admet-2088	571	27	dacarbazine	dacarbazine	NOUN
admet-2088	571	28	solution	solution	NOUN
admet-2088	571	29	at	at	ADP
admet-2088	571	30	the	the	DET
admet-2088	571	31	same	same	ADJ
admet-2088	571	32	concentration	concentration	NOUN
admet-2088	571	33	level	level	NOUN
admet-2088	571	34	.	.	PUNCT
admet-2088	572	1	in	in	ADP
admet-2088	572	2	addition	addition	NOUN
admet-2088	572	3	,	,	PUNCT
admet-2088	572	4	the	the	DET
admet-2088	572	5	number	number	NOUN
admet-2088	572	6	of	of	ADP
admet-2088	572	7	late	late	ADJ
admet-2088	572	8	apoptotic	apoptotic	ADJ
admet-2088	572	9	cells	cell	NOUN
admet-2088	572	10	was	be	AUX
admet-2088	572	11	found	find	VERB
admet-2088	572	12	to	to	PART
admet-2088	572	13	be	be	AUX
admet-2088	572	14	much	much	ADV
admet-2088	572	15	higher	high	ADJ
admet-2088	572	16	for	for	ADP
admet-2088	572	17	the	the	DET
admet-2088	572	18	coated	coat	VERB
admet-2088	572	19	liposomes	liposome	NOUN
admet-2088	572	20	at	at	ADP
admet-2088	572	21	45.16	45.16	NUM
admet-2088	572	22	%	%	NOUN
admet-2088	572	23	than	than	ADP
admet-2088	572	24	that	that	PRON
admet-2088	572	25	of	of	ADP
admet-2088	572	26	the	the	DET
admet-2088	572	27	dacarbazine	dacarbazine	NOUN
admet-2088	572	28	solution	solution	NOUN
admet-2088	572	29	(	(	PUNCT
admet-2088	572	30	8.43	8.43	NUM
admet-2088	572	31	%	%	NOUN
admet-2088	572	32	)	)	PUNCT
admet-2088	572	33	.	.	PUNCT
admet-2088	573	1	moreover	moreover	ADV
admet-2088	573	2	,	,	PUNCT
admet-2088	573	3	the	the	DET
admet-2088	573	4	coated	coat	VERB
admet-2088	573	5	liposomes	liposome	NOUN
admet-2088	573	6	demonstrated	demonstrate	VERB
admet-2088	573	7	significantly	significantly	ADV
admet-2088	573	8	higher	high	ADJ
admet-2088	573	9	inhibition	inhibition	NOUN
admet-2088	573	10	of	of	ADP
admet-2088	573	11	cell	cell	NOUN
admet-2088	573	12	migration	migration	NOUN
admet-2088	573	13	and	and	CCONJ
admet-2088	573	14	proliferation	proliferation	NOUN
admet-2088	573	15	,	,	PUNCT
admet-2088	573	16	indicating	indicate	VERB
admet-2088	573	17	their	their	PRON
admet-2088	573	18	ability	ability	NOUN
admet-2088	573	19	against	against	ADP
admet-2088	573	20	metastasis	metastasis	NOUN
admet-2088	573	21	.	.	PUNCT
admet-2088	574	1	eugenol	eugenol	PROPN
admet-2088	574	2	was	be	AUX
admet-2088	574	3	found	find	VERB
admet-2088	574	4	to	to	PART
admet-2088	574	5	downregulate	downregulate	VERB
admet-2088	574	6	surviving	survive	VERB
admet-2088	574	7	protein	protein	NOUN
admet-2088	574	8	,	,	PUNCT
admet-2088	574	9	thereby	thereby	ADV
admet-2088	574	10	allowing	allow	VERB
admet-2088	574	11	dacarbazine	dacarbazine	NOUN
admet-2088	574	12	to	to	PART
admet-2088	574	13	function	function	VERB
admet-2088	574	14	in	in	ADP
admet-2088	574	15	an	an	DET
admet-2088	574	16	efficient	efficient	ADJ
admet-2088	574	17	manner	manner	NOUN
admet-2088	575	1	[	[	X
admet-2088	575	2	209	209	NUM
admet-2088	575	3	]	]	PUNCT
admet-2088	575	4	.	.	PUNCT
admet-2088	576	1	in	in	ADP
admet-2088	576	2	a	a	DET
admet-2088	576	3	separate	separate	ADJ
admet-2088	576	4	study	study	NOUN
admet-2088	576	5	,	,	PUNCT
admet-2088	576	6	5fu	5fu	NOUN
admet-2088	576	7	-	-	PUNCT
admet-2088	576	8	loaded	load	VERB
admet-2088	576	9	liposomes	liposome	NOUN
admet-2088	576	10	were	be	AUX
admet-2088	576	11	developed	develop	VERB
admet-2088	576	12	and	and	CCONJ
admet-2088	576	13	subsequently	subsequently	ADV
admet-2088	576	14	surface	surface	PROPN
admet-2088	576	15	admet	admet	PROPN
admet-2088	576	16	&	&	CCONJ
admet-2088	576	17	dmpk	dmpk	PROPN
admet-2088	576	18	12(1	12(1	PROPN
admet-2088	576	19	)	)	PUNCT
admet-2088	576	20	(	(	PUNCT
admet-2088	576	21	2024	2024	NUM
admet-2088	576	22	)	)	PUNCT
admet-2088	576	23	107	107	NUM
admet-2088	576	24	-	-	SYM
admet-2088	576	25	150	150	NUM
admet-2088	576	26	nanomaterial	nanomaterial	NOUN
admet-2088	576	27	-	-	PUNCT
admet-2088	576	28	based	base	VERB
admet-2088	576	29	drug	drug	NOUN
admet-2088	576	30	delivery	delivery	NOUN
admet-2088	576	31	systems	system	NOUN
admet-2088	576	32	for	for	ADP
admet-2088	576	33	melanoma	melanoma	NOUN
admet-2088	576	34	therapy	therapy	NOUN
admet-2088	576	35	doi	doi	NOUN
admet-2088	576	36	:	:	PUNCT
admet-2088	576	37	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	576	38	129	129	NUM
admet-2088	576	39	functionalized	functionalize	VERB
admet-2088	576	40	with	with	ADP
admet-2088	576	41	as1411	as1411	ADJ
admet-2088	576	42	aptamer	aptamer	NOUN
admet-2088	576	43	for	for	ADP
admet-2088	576	44	the	the	DET
admet-2088	576	45	treatment	treatment	NOUN
admet-2088	576	46	of	of	ADP
admet-2088	576	47	basal	basal	ADJ
admet-2088	576	48	cell	cell	NOUN
admet-2088	576	49	carcinomas	carcinoma	NOUN
admet-2088	576	50	.	.	PUNCT
admet-2088	577	1	the	the	DET
admet-2088	577	2	functionalization	functionalization	NOUN
admet-2088	577	3	of	of	ADP
admet-2088	577	4	liposomes	liposome	NOUN
admet-2088	577	5	with	with	ADP
admet-2088	577	6	as1411	as1411	ADJ
admet-2088	577	7	aptamer	aptamer	NOUN
admet-2088	577	8	not	not	PART
admet-2088	577	9	only	only	ADV
admet-2088	577	10	improved	improve	VERB
admet-2088	577	11	the	the	DET
admet-2088	577	12	stability	stability	NOUN
admet-2088	577	13	of	of	ADP
admet-2088	577	14	the	the	DET
admet-2088	577	15	liposomes	liposome	NOUN
admet-2088	577	16	but	but	CCONJ
admet-2088	577	17	also	also	ADV
admet-2088	577	18	provided	provide	VERB
admet-2088	577	19	a	a	DET
admet-2088	577	20	supplementary	supplementary	ADJ
admet-2088	577	21	steric	steric	ADJ
admet-2088	577	22	barrier	barrier	NOUN
admet-2088	577	23	,	,	PUNCT
admet-2088	577	24	resulting	result	VERB
admet-2088	577	25	in	in	ADP
admet-2088	577	26	the	the	DET
admet-2088	577	27	lower	low	ADJ
admet-2088	577	28	cumulative	cumulative	ADJ
admet-2088	577	29	release	release	NOUN
admet-2088	577	30	of	of	ADP
admet-2088	577	31	5	5	NUM
admet-2088	577	32	-	-	PUNCT
admet-2088	577	33	fu	fu	NOUN
admet-2088	577	34	.	.	PUNCT
admet-2088	578	1	these	these	DET
admet-2088	578	2	liposomes	liposome	NOUN
admet-2088	578	3	demonstrated	demonstrate	VERB
admet-2088	578	4	higher	high	ADJ
admet-2088	578	5	efficiency	efficiency	NOUN
admet-2088	578	6	in	in	ADP
admet-2088	578	7	terms	term	NOUN
admet-2088	578	8	of	of	ADP
admet-2088	578	9	in	in	ADP
admet-2088	578	10	vitro	vitro	X
admet-2088	578	11	cell	cell	NOUN
admet-2088	578	12	viability	viability	NOUN
admet-2088	578	13	,	,	PUNCT
admet-2088	578	14	apoptotic	apoptotic	ADJ
admet-2088	578	15	effects	effect	NOUN
admet-2088	578	16	and	and	CCONJ
admet-2088	578	17	targeting	target	VERB
admet-2088	578	18	capability	capability	NOUN
admet-2088	578	19	on	on	ADP
admet-2088	578	20	human	human	ADJ
admet-2088	578	21	dermal	dermal	NOUN
admet-2088	578	22	fibroblasts	fibroblast	NOUN
admet-2088	578	23	and	and	CCONJ
admet-2088	578	24	basal	basal	ADJ
admet-2088	578	25	cell	cell	NOUN
admet-2088	578	26	carcinoma	carcinoma	NOUN
admet-2088	578	27	te	te	ADP
admet-2088	578	28	354	354	NUM
admet-2088	578	29	cell	cell	NOUN
admet-2088	578	30	line	line	NOUN
admet-2088	578	31	than	than	ADP
admet-2088	578	32	liposomes	liposome	NOUN
admet-2088	578	33	without	without	ADP
admet-2088	578	34	functionalization	functionalization	NOUN
admet-2088	578	35	[	[	X
admet-2088	578	36	210	210	NUM
admet-2088	578	37	]	]	PUNCT
admet-2088	578	38	.	.	PUNCT
admet-2088	579	1	in	in	ADP
admet-2088	579	2	a	a	DET
admet-2088	579	3	different	different	ADJ
admet-2088	579	4	investigation	investigation	NOUN
admet-2088	579	5	,	,	PUNCT
admet-2088	579	6	solid	solid	ADJ
admet-2088	579	7	lipid	lipid	PROPN
admet-2088	579	8	nps	nps	PROPN
admet-2088	579	9	(	(	PUNCT
admet-2088	579	10	liposomes	liposome	NOUN
admet-2088	579	11	)	)	PUNCT
admet-2088	579	12	were	be	AUX
admet-2088	579	13	developed	develop	VERB
admet-2088	579	14	for	for	ADP
admet-2088	579	15	the	the	DET
admet-2088	579	16	adsorption	adsorption	NOUN
admet-2088	579	17	of	of	ADP
admet-2088	579	18	tumourspecific	tumourspecific	ADJ
admet-2088	579	19	proteins	protein	NOUN
admet-2088	579	20	in	in	ADP
admet-2088	579	21	murine	murine	ADJ
admet-2088	579	22	models	model	NOUN
admet-2088	579	23	of	of	ADP
admet-2088	579	24	the	the	DET
admet-2088	579	25	subcutaneous	subcutaneous	ADJ
admet-2088	579	26	melanoma	melanoma	NOUN
admet-2088	579	27	model	model	NOUN
admet-2088	579	28	(	(	PUNCT
admet-2088	579	29	b16	b16	PROPN
admet-2088	579	30	-	-	PUNCT
admet-2088	579	31	f10	f10	NOUN
admet-2088	579	32	)	)	PUNCT
admet-2088	579	33	and	and	CCONJ
admet-2088	579	34	human	human	ADJ
admet-2088	579	35	lung	lung	NOUN
admet-2088	579	36	carcinoma	carcinoma	PROPN
admet-2088	579	37	xenograft	xenograft	PROPN
admet-2088	579	38	model	model	PROPN
admet-2088	579	39	(	(	PUNCT
admet-2088	579	40	a549	a549	PROPN
admet-2088	579	41	)	)	PUNCT
admet-2088	579	42	that	that	PRON
admet-2088	579	43	could	could	AUX
admet-2088	579	44	not	not	PART
admet-2088	579	45	be	be	AUX
admet-2088	579	46	detectable	detectable	ADJ
admet-2088	579	47	by	by	ADP
admet-2088	579	48	plasma	plasma	NOUN
admet-2088	579	49	analysis	analysis	NOUN
admet-2088	579	50	.	.	PUNCT
admet-2088	580	1	after	after	ADP
admet-2088	580	2	the	the	DET
admet-2088	580	3	iv	iv	NUM
admet-2088	580	4	administration	administration	NOUN
admet-2088	580	5	to	to	ADP
admet-2088	580	6	tumour	tumour	NOUN
admet-2088	580	7	-	-	PUNCT
admet-2088	580	8	bearing	bear	VERB
admet-2088	580	9	mice	mouse	NOUN
admet-2088	580	10	,	,	PUNCT
admet-2088	580	11	the	the	DET
admet-2088	580	12	blood	blood	NOUN
admet-2088	580	13	circulating	circulate	VERB
admet-2088	580	14	liposomes	liposome	NOUN
admet-2088	580	15	captured	capture	VERB
admet-2088	580	16	and	and	CCONJ
admet-2088	580	17	amplified	amplify	VERB
admet-2088	580	18	a	a	DET
admet-2088	580	19	wide	wide	ADJ
admet-2088	580	20	range	range	NOUN
admet-2088	580	21	of	of	ADP
admet-2088	580	22	different	different	ADJ
admet-2088	580	23	proteins	protein	NOUN
admet-2088	580	24	,	,	PUNCT
admet-2088	580	25	including	include	VERB
admet-2088	580	26	tumour	tumour	NOUN
admet-2088	580	27	-	-	PUNCT
admet-2088	580	28	specific	specific	ADJ
admet-2088	580	29	proteins	protein	NOUN
admet-2088	580	30	(	(	PUNCT
admet-2088	580	31	intracellular	intracellular	ADJ
admet-2088	580	32	products	product	NOUN
admet-2088	580	33	of	of	ADP
admet-2088	580	34	tissue	tissue	NOUN
admet-2088	580	35	leakage	leakage	NOUN
admet-2088	580	36	)	)	PUNCT
admet-2088	580	37	called	call	VERB
admet-2088	580	38	protein	protein	NOUN
admet-2088	580	39	corona	corona	NOUN
admet-2088	580	40	.	.	PUNCT
admet-2088	581	1	thus	thus	ADV
admet-2088	581	2	,	,	PUNCT
admet-2088	581	3	the	the	DET
admet-2088	581	4	in	in	ADP
admet-2088	581	5	vivo	vivo	NOUN
admet-2088	581	6	liposome	liposome	NOUN
admet-2088	581	7	protein	protein	NOUN
admet-2088	581	8	corona	corona	NOUN
admet-2088	581	9	could	could	AUX
admet-2088	581	10	be	be	AUX
admet-2088	581	11	an	an	DET
admet-2088	581	12	extraordinary	extraordinary	ADJ
admet-2088	581	13	tool	tool	NOUN
admet-2088	581	14	to	to	PART
admet-2088	581	15	enrich	enrich	VERB
admet-2088	581	16	blood	blood	NOUN
admet-2088	581	17	proteomic	proteomic	ADJ
admet-2088	581	18	analysis	analysis	NOUN
admet-2088	581	19	and	and	CCONJ
admet-2088	581	20	help	help	NOUN
admet-2088	581	21	in	in	ADP
admet-2088	581	22	the	the	DET
admet-2088	581	23	discovery	discovery	NOUN
admet-2088	581	24	of	of	ADP
admet-2088	581	25	potential	potential	ADJ
admet-2088	581	26	biomarkers	biomarker	NOUN
admet-2088	581	27	for	for	ADP
admet-2088	581	28	various	various	ADJ
admet-2088	581	29	disease	disease	NOUN
admet-2088	581	30	models	model	NOUN
admet-2088	581	31	[	[	X
admet-2088	581	32	211	211	NUM
admet-2088	581	33	]	]	PUNCT
admet-2088	581	34	.	.	PUNCT
admet-2088	582	1	niosomes	niosome	NOUN
admet-2088	582	2	niosomes	niosome	NOUN
admet-2088	582	3	are	be	AUX
admet-2088	582	4	non	non	ADJ
admet-2088	582	5	-	-	ADJ
admet-2088	582	6	ionic	ionic	ADJ
admet-2088	582	7	surfactant	surfactant	NOUN
admet-2088	582	8	-	-	PUNCT
admet-2088	582	9	based	base	VERB
admet-2088	582	10	vesicles	vesicle	NOUN
admet-2088	582	11	that	that	PRON
admet-2088	582	12	are	be	AUX
admet-2088	582	13	developed	develop	VERB
admet-2088	582	14	to	to	PART
admet-2088	582	15	circumvent	circumvent	VERB
admet-2088	582	16	the	the	DET
admet-2088	582	17	stability	stability	NOUN
admet-2088	582	18	issue	issue	NOUN
admet-2088	582	19	of	of	ADP
admet-2088	582	20	liposomes	liposome	NOUN
admet-2088	582	21	.	.	PUNCT
admet-2088	583	1	regarding	regard	VERB
admet-2088	583	2	cutaneous	cutaneous	ADJ
admet-2088	583	3	permeation	permeation	NOUN
admet-2088	583	4	for	for	ADP
admet-2088	583	5	melanoma	melanoma	NOUN
admet-2088	583	6	treatment	treatment	NOUN
admet-2088	583	7	,	,	PUNCT
admet-2088	583	8	niosomes	niosome	NOUN
admet-2088	583	9	outperform	outperform	VERB
admet-2088	583	10	liposomes	liposome	NOUN
admet-2088	583	11	in	in	ADP
admet-2088	583	12	terms	term	NOUN
admet-2088	583	13	of	of	ADP
admet-2088	583	14	drug	drug	NOUN
admet-2088	583	15	entrapment	entrapment	ADJ
admet-2088	583	16	efficiency	efficiency	NOUN
admet-2088	583	17	and	and	CCONJ
admet-2088	583	18	permeability	permeability	NOUN
admet-2088	583	19	due	due	ADP
admet-2088	583	20	to	to	ADP
admet-2088	583	21	non	non	ADJ
admet-2088	583	22	-	-	ADJ
admet-2088	583	23	ionic	ionic	ADJ
admet-2088	583	24	surfactants	surfactant	NOUN
admet-2088	583	25	that	that	PRON
admet-2088	583	26	change	change	VERB
admet-2088	583	27	the	the	DET
admet-2088	583	28	stratum	stratum	NOUN
admet-2088	583	29	corneum	corneum	NOUN
admet-2088	583	30	integrity	integrity	NOUN
admet-2088	583	31	[	[	X
admet-2088	583	32	212	212	NUM
admet-2088	583	33	]	]	PUNCT
admet-2088	583	34	.	.	PUNCT
admet-2088	584	1	they	they	PRON
admet-2088	584	2	have	have	VERB
admet-2088	584	3	the	the	DET
admet-2088	584	4	additional	additional	ADJ
admet-2088	584	5	advantages	advantage	NOUN
admet-2088	584	6	of	of	ADP
admet-2088	584	7	low	low	ADJ
admet-2088	584	8	production	production	NOUN
admet-2088	584	9	cost	cost	NOUN
admet-2088	584	10	,	,	PUNCT
admet-2088	584	11	longer	long	ADJ
admet-2088	584	12	self	self	NOUN
admet-2088	584	13	-	-	PUNCT
admet-2088	584	14	life	life	NOUN
admet-2088	584	15	,	,	PUNCT
admet-2088	584	16	and	and	CCONJ
admet-2088	584	17	the	the	DET
admet-2088	584	18	capability	capability	NOUN
admet-2088	584	19	of	of	ADP
admet-2088	584	20	controlling	control	VERB
admet-2088	584	21	their	their	PRON
admet-2088	584	22	bilayer	bilayer	NOUN
admet-2088	584	23	fluidity	fluidity	NOUN
admet-2088	584	24	and	and	CCONJ
admet-2088	584	25	microviscosity	microviscosity	NOUN
admet-2088	584	26	[	[	X
admet-2088	584	27	213	213	NUM
admet-2088	584	28	]	]	PUNCT
admet-2088	584	29	.	.	PUNCT
admet-2088	584	30	chermahini	chermahini	PROPN
admet-2088	584	31	and	and	CCONJ
admet-2088	584	32	najaf	najaf	PROPN
admet-2088	585	1	[	[	X
admet-2088	585	2	214	214	NUM
admet-2088	585	3	]	]	PUNCT
admet-2088	585	4	have	have	AUX
admet-2088	585	5	developed	develop	VERB
admet-2088	585	6	5fu	5fu	ADV
admet-2088	585	7	-	-	PUNCT
admet-2088	585	8	loaded	load	VERB
admet-2088	585	9	niosomes	niosome	NOUN
admet-2088	585	10	for	for	ADP
admet-2088	585	11	the	the	DET
admet-2088	585	12	treatment	treatment	NOUN
admet-2088	585	13	of	of	ADP
admet-2088	585	14	basal	basal	ADJ
admet-2088	585	15	cell	cell	NOUN
admet-2088	585	16	skin	skin	NOUN
admet-2088	585	17	cancer	cancer	NOUN
admet-2088	585	18	.	.	PUNCT
admet-2088	586	1	the	the	DET
admet-2088	586	2	encapsulation	encapsulation	NOUN
admet-2088	586	3	of	of	ADP
admet-2088	586	4	5fu	5fu	NOUN
admet-2088	586	5	inside	inside	ADP
admet-2088	586	6	the	the	DET
admet-2088	586	7	niosomes	niosome	NOUN
admet-2088	586	8	not	not	PART
admet-2088	586	9	only	only	ADV
admet-2088	586	10	improved	improve	VERB
admet-2088	586	11	the	the	DET
admet-2088	586	12	stability	stability	NOUN
admet-2088	586	13	(	(	PUNCT
admet-2088	586	14	with	with	ADP
admet-2088	586	15	a	a	DET
admet-2088	586	16	zeta	zeta	NOUN
admet-2088	586	17	potential	potential	NOUN
admet-2088	586	18	of	of	ADP
admet-2088	586	19	60	60	NUM
admet-2088	586	20	)	)	PUNCT
admet-2088	586	21	but	but	CCONJ
admet-2088	586	22	also	also	ADV
admet-2088	586	23	enhanced	enhance	VERB
admet-2088	586	24	the	the	DET
admet-2088	586	25	skin	skin	NOUN
admet-2088	586	26	permeation	permeation	NOUN
admet-2088	586	27	ability	ability	NOUN
admet-2088	586	28	.	.	PUNCT
admet-2088	587	1	to	to	PART
admet-2088	587	2	circumvent	circumvent	VERB
admet-2088	587	3	the	the	DET
admet-2088	587	4	poor	poor	ADJ
admet-2088	587	5	percutaneous	percutaneous	ADJ
admet-2088	587	6	permeation	permeation	NOUN
admet-2088	587	7	,	,	PUNCT
admet-2088	587	8	sulforaphane	sulforaphane	NOUN
admet-2088	587	9	,	,	PUNCT
admet-2088	587	10	a	a	DET
admet-2088	587	11	natural	natural	ADJ
admet-2088	587	12	dietary	dietary	ADJ
admet-2088	587	13	isothiocyanate	isothiocyanate	NOUN
admet-2088	587	14	was	be	AUX
admet-2088	587	15	loaded	load	VERB
admet-2088	587	16	into	into	ADP
admet-2088	587	17	ultradeformable	ultradeformable	ADJ
admet-2088	587	18	vesicles	vesicle	NOUN
admet-2088	587	19	such	such	ADJ
admet-2088	587	20	as	as	ADP
admet-2088	587	21	ethosomes	ethosome	NOUN
admet-2088	587	22	and	and	CCONJ
admet-2088	587	23	transferosome	transferosome	NOUN
admet-2088	587	24	.	.	PUNCT
admet-2088	588	1	out	out	ADP
admet-2088	588	2	of	of	ADP
admet-2088	588	3	the	the	DET
admet-2088	588	4	two	two	NUM
admet-2088	588	5	types	type	NOUN
admet-2088	588	6	of	of	ADP
admet-2088	588	7	vesicles	vesicle	NOUN
admet-2088	588	8	,	,	PUNCT
admet-2088	588	9	ethosomes	ethosome	NOUN
admet-2088	588	10	with	with	ADP
admet-2088	588	11	2	2	NUM
admet-2088	588	12	%	%	NOUN
admet-2088	588	13	phospholipon	phospholipon	ADP
admet-2088	588	14	90	90	NUM
admet-2088	588	15	g	g	NOUN
admet-2088	588	16	and	and	CCONJ
admet-2088	588	17	40	40	NUM
admet-2088	588	18	%	%	NOUN
admet-2088	588	19	ethanol	ethanol	NOUN
admet-2088	588	20	showed	show	VERB
admet-2088	588	21	higher	high	ADJ
admet-2088	588	22	stability	stability	NOUN
admet-2088	588	23	than	than	ADP
admet-2088	588	24	transferosomes	transferosome	NOUN
admet-2088	588	25	.	.	PUNCT
admet-2088	589	1	drug	drug	NOUN
admet-2088	589	2	-	-	PUNCT
admet-2088	589	3	loaded	load	VERB
admet-2088	589	4	ethosomes	ethosome	NOUN
admet-2088	589	5	demonstrated	demonstrate	VERB
admet-2088	589	6	enhanced	enhance	VERB
admet-2088	589	7	percutaneous	percutaneous	ADJ
admet-2088	589	8	permeation	permeation	NOUN
admet-2088	589	9	of	of	ADP
admet-2088	589	10	sulforaphane	sulforaphane	NOUN
admet-2088	589	11	through	through	ADP
admet-2088	589	12	the	the	DET
admet-2088	589	13	epidermis	epidermis	NOUN
admet-2088	589	14	membrane	membrane	NOUN
admet-2088	589	15	and	and	CCONJ
admet-2088	589	16	human	human	ADJ
admet-2088	589	17	stratum	stratum	NOUN
admet-2088	589	18	corneum	corneum	NOUN
admet-2088	589	19	.	.	PUNCT
admet-2088	590	1	in	in	ADP
admet-2088	590	2	addition	addition	NOUN
admet-2088	590	3	,	,	PUNCT
admet-2088	590	4	in	in	ADP
admet-2088	590	5	vitro	vitro	X
admet-2088	590	6	anticancer	anticancer	NOUN
admet-2088	590	7	study	study	NOUN
admet-2088	590	8	on	on	ADP
admet-2088	590	9	sk	sk	PROPN
admet-2088	590	10	-	-	PUNCT
admet-2088	590	11	mel	mel	NOUN
admet-2088	590	12	28	28	NUM
admet-2088	590	13	cell	cell	NOUN
admet-2088	590	14	lines	line	NOUN
admet-2088	590	15	revealed	reveal	VERB
admet-2088	590	16	the	the	DET
admet-2088	590	17	ethosomes	ethosome	NOUN
admet-2088	590	18	had	have	VERB
admet-2088	590	19	improved	improve	VERB
admet-2088	590	20	anticancer	anticancer	NOUN
admet-2088	590	21	activity	activity	NOUN
admet-2088	590	22	due	due	ADP
admet-2088	590	23	to	to	ADP
admet-2088	590	24	the	the	DET
admet-2088	590	25	antiproliferative	antiproliferative	ADJ
admet-2088	590	26	activity	activity	NOUN
admet-2088	590	27	of	of	ADP
admet-2088	590	28	sulforaphane	sulforaphane	NOUN
admet-2088	590	29	[	[	X
admet-2088	590	30	215	215	NUM
admet-2088	590	31	]	]	PUNCT
admet-2088	590	32	.	.	PUNCT
admet-2088	591	1	solid	solid	ADJ
admet-2088	591	2	lipid	lipid	ADJ
admet-2088	591	3	nanoparticles	nanoparticle	NOUN
admet-2088	591	4	slns	slns	NOUN
admet-2088	591	5	are	be	AUX
admet-2088	591	6	colloidal	colloidal	NOUN
admet-2088	591	7	particles	particle	NOUN
admet-2088	591	8	prepared	prepare	VERB
admet-2088	591	9	from	from	ADP
admet-2088	591	10	physiological	physiological	ADJ
admet-2088	591	11	solid	solid	ADJ
admet-2088	591	12	lipids	lipid	NOUN
admet-2088	591	13	(	(	PUNCT
admet-2088	591	14	liquid	liquid	NOUN
admet-2088	591	15	at	at	ADP
admet-2088	591	16	room	room	NOUN
admet-2088	591	17	temperature	temperature	NOUN
admet-2088	591	18	but	but	CCONJ
admet-2088	591	19	solid	solid	ADJ
admet-2088	591	20	at	at	ADP
admet-2088	591	21	body	body	NOUN
admet-2088	591	22	temperature	temperature	NOUN
admet-2088	591	23	)	)	PUNCT
admet-2088	591	24	such	such	ADJ
admet-2088	591	25	as	as	ADP
admet-2088	591	26	tripalmitin	tripalmitin	NOUN
admet-2088	591	27	,	,	PUNCT
admet-2088	591	28	trimyristin	trimyristin	NOUN
admet-2088	591	29	,	,	PUNCT
admet-2088	591	30	stearic	stearic	ADJ
admet-2088	591	31	acid	acid	NOUN
admet-2088	591	32	,	,	PUNCT
admet-2088	591	33	etc	etc	X
admet-2088	591	34	,	,	PUNCT
admet-2088	591	35	surfactants	surfactant	NOUN
admet-2088	591	36	(	(	PUNCT
admet-2088	591	37	e.g.	e.g.	ADV
admet-2088	591	38	,	,	PUNCT
admet-2088	591	39	poloxamer	poloxamer	NOUN
admet-2088	591	40	)	)	PUNCT
admet-2088	591	41	employing	employ	VERB
admet-2088	591	42	most	most	ADV
admet-2088	591	43	common	common	ADJ
admet-2088	591	44	techniques	technique	NOUN
admet-2088	591	45	such	such	ADJ
admet-2088	591	46	as	as	ADP
admet-2088	591	47	homogenization	homogenization	NOUN
admet-2088	591	48	,	,	PUNCT
admet-2088	591	49	ultrasonication	ultrasonication	NOUN
admet-2088	591	50	and	and	CCONJ
admet-2088	591	51	emulsification	emulsification	NOUN
admet-2088	591	52	[	[	X
admet-2088	591	53	216	216	NUM
admet-2088	591	54	]	]	PUNCT
admet-2088	591	55	.	.	PUNCT
admet-2088	592	1	the	the	DET
admet-2088	592	2	potential	potential	ADJ
admet-2088	592	3	advantages	advantage	NOUN
admet-2088	592	4	of	of	ADP
admet-2088	592	5	slns	slns	NOUN
admet-2088	592	6	are	be	AUX
admet-2088	592	7	that	that	SCONJ
admet-2088	592	8	protection	protection	NOUN
admet-2088	592	9	of	of	ADP
admet-2088	592	10	labile	labile	ADJ
admet-2088	592	11	drugs	drug	NOUN
admet-2088	592	12	from	from	ADP
admet-2088	592	13	degradation	degradation	NOUN
admet-2088	592	14	,	,	PUNCT
admet-2088	592	15	organic	organic	ADJ
admet-2088	592	16	solvents	solvent	NOUN
admet-2088	592	17	-	-	PUNCT
admet-2088	592	18	free	free	ADJ
admet-2088	592	19	preparation	preparation	NOUN
admet-2088	592	20	,	,	PUNCT
admet-2088	592	21	higher	high	ADJ
admet-2088	592	22	drug	drug	NOUN
admet-2088	592	23	loading	loading	NOUN
admet-2088	592	24	,	,	PUNCT
admet-2088	592	25	absence	absence	NOUN
admet-2088	592	26	of	of	ADP
admet-2088	592	27	toxicity	toxicity	NOUN
admet-2088	592	28	due	due	ADP
admet-2088	592	29	to	to	ADP
admet-2088	592	30	the	the	DET
admet-2088	592	31	presence	presence	NOUN
admet-2088	592	32	of	of	ADP
admet-2088	592	33	physiological	physiological	ADJ
admet-2088	592	34	lipids	lipid	NOUN
admet-2088	592	35	,	,	PUNCT
admet-2088	592	36	excellent	excellent	ADJ
admet-2088	592	37	tolerability	tolerability	NOUN
admet-2088	592	38	,	,	PUNCT
admet-2088	592	39	controlled	control	VERB
admet-2088	592	40	release	release	NOUN
admet-2088	592	41	,	,	PUNCT
admet-2088	592	42	can	can	AUX
admet-2088	592	43	be	be	AUX
admet-2088	592	44	scaled	scale	VERB
admet-2088	592	45	-	-	PUNCT
admet-2088	592	46	up	up	NOUN
admet-2088	592	47	with	with	ADP
admet-2088	592	48	reproducibility	reproducibility	NOUN
admet-2088	592	49	,	,	PUNCT
admet-2088	592	50	and	and	CCONJ
admet-2088	592	51	higher	high	ADJ
admet-2088	592	52	physical	physical	ADJ
admet-2088	592	53	stability	stability	NOUN
admet-2088	592	54	compared	compare	VERB
admet-2088	592	55	to	to	ADP
admet-2088	592	56	liposomes	liposome	NOUN
admet-2088	592	57	[	[	X
admet-2088	592	58	217,218	217,218	NUM
admet-2088	592	59	]	]	PUNCT
admet-2088	592	60	.	.	PUNCT
admet-2088	593	1	in	in	ADP
admet-2088	593	2	addition	addition	NOUN
admet-2088	593	3	,	,	PUNCT
admet-2088	593	4	the	the	DET
admet-2088	593	5	characteristics	characteristic	NOUN
admet-2088	593	6	of	of	ADP
admet-2088	593	7	slns	slns	PROPN
admet-2088	593	8	are	be	AUX
admet-2088	593	9	most	most	ADV
admet-2088	593	10	favoured	favour	VERB
admet-2088	593	11	by	by	ADP
admet-2088	593	12	hydrophobic	hydrophobic	NOUN
admet-2088	593	13	drugs	drug	NOUN
admet-2088	593	14	with	with	ADP
admet-2088	593	15	high	high	ADJ
admet-2088	593	16	surface	surface	NOUN
admet-2088	593	17	area	area	NOUN
admet-2088	593	18	and	and	CCONJ
admet-2088	593	19	drug	drug	NOUN
admet-2088	593	20	loading	loading	NOUN
admet-2088	593	21	[	[	X
admet-2088	593	22	219	219	NUM
admet-2088	593	23	]	]	PUNCT
admet-2088	593	24	.	.	PUNCT
admet-2088	594	1	they	they	PRON
admet-2088	594	2	also	also	ADV
admet-2088	594	3	provide	provide	VERB
admet-2088	594	4	excellent	excellent	ADJ
admet-2088	594	5	opportunities	opportunity	NOUN
admet-2088	594	6	for	for	ADP
admet-2088	594	7	surface	surface	NOUN
admet-2088	594	8	modification	modification	NOUN
admet-2088	594	9	.	.	PUNCT
admet-2088	595	1	for	for	ADP
admet-2088	595	2	instance	instance	NOUN
admet-2088	595	3	,	,	PUNCT
admet-2088	595	4	surface	surface	NOUN
admet-2088	595	5	modification	modification	NOUN
admet-2088	595	6	with	with	ADP
admet-2088	595	7	peg	peg	NOUN
admet-2088	595	8	molecules	molecule	NOUN
admet-2088	595	9	stops	stop	VERB
admet-2088	595	10	the	the	DET
admet-2088	595	11	opsonization	opsonization	NOUN
admet-2088	595	12	by	by	ADP
admet-2088	595	13	reticuloendothelial	reticuloendothelial	ADJ
admet-2088	595	14	cells	cell	NOUN
admet-2088	595	15	,	,	PUNCT
admet-2088	595	16	thus	thus	ADV
admet-2088	595	17	improving	improve	VERB
admet-2088	595	18	circulation	circulation	NOUN
admet-2088	595	19	time	time	NOUN
admet-2088	595	20	and	and	CCONJ
admet-2088	595	21	bioavailability	bioavailability	NOUN
admet-2088	595	22	[	[	X
admet-2088	595	23	186	186	NUM
admet-2088	595	24	]	]	PUNCT
admet-2088	595	25	.	.	PUNCT
admet-2088	596	1	however	however	ADV
admet-2088	596	2	,	,	PUNCT
admet-2088	596	3	they	they	PRON
admet-2088	596	4	have	have	VERB
admet-2088	596	5	issues	issue	NOUN
admet-2088	596	6	with	with	ADP
admet-2088	596	7	poor	poor	ADJ
admet-2088	596	8	drug	drug	NOUN
admet-2088	596	9	loading	loading	NOUN
admet-2088	596	10	and	and	CCONJ
admet-2088	596	11	leakage	leakage	NOUN
admet-2088	596	12	of	of	ADP
admet-2088	596	13	drugs	drug	NOUN
admet-2088	596	14	during	during	ADP
admet-2088	596	15	storage	storage	NOUN
admet-2088	596	16	.	.	PUNCT
admet-2088	597	1	the	the	DET
admet-2088	597	2	combination	combination	NOUN
admet-2088	597	3	of	of	ADP
admet-2088	597	4	drugs	drug	NOUN
admet-2088	597	5	against	against	ADP
admet-2088	597	6	the	the	DET
admet-2088	597	7	treatment	treatment	NOUN
admet-2088	597	8	of	of	ADP
admet-2088	597	9	cancer	cancer	NOUN
admet-2088	597	10	is	be	AUX
admet-2088	597	11	a	a	DET
admet-2088	597	12	bone	bone	NOUN
admet-2088	597	13	as	as	SCONJ
admet-2088	597	14	they	they	PRON
admet-2088	597	15	provide	provide	VERB
admet-2088	597	16	a	a	DET
admet-2088	597	17	potential	potential	ADJ
admet-2088	597	18	synergistic	synergistic	ADJ
admet-2088	597	19	effect	effect	NOUN
admet-2088	597	20	.	.	PUNCT
admet-2088	598	1	however	however	ADV
admet-2088	598	2	,	,	PUNCT
admet-2088	598	3	it	it	PRON
admet-2088	598	4	is	be	AUX
admet-2088	598	5	limited	limit	VERB
admet-2088	598	6	by	by	ADP
admet-2088	598	7	the	the	DET
admet-2088	598	8	absence	absence	NOUN
admet-2088	598	9	of	of	ADP
admet-2088	598	10	a	a	DET
admet-2088	598	11	suitable	suitable	ADJ
admet-2088	598	12	carrier	carrier	NOUN
admet-2088	598	13	that	that	PRON
admet-2088	598	14	can	can	AUX
admet-2088	598	15	deliver	deliver	VERB
admet-2088	598	16	drugs	drug	NOUN
admet-2088	598	17	precisely	precisely	ADV
admet-2088	598	18	and	and	CCONJ
admet-2088	598	19	helps	help	VERB
admet-2088	598	20	to	to	PART
admet-2088	598	21	accumulate	accumulate	VERB
admet-2088	598	22	drugs	drug	NOUN
admet-2088	598	23	in	in	ADP
admet-2088	598	24	the	the	DET
admet-2088	598	25	cancerous	cancerous	ADJ
admet-2088	598	26	cells	cell	NOUN
admet-2088	598	27	.	.	PUNCT
admet-2088	599	1	in	in	ADP
admet-2088	599	2	this	this	DET
admet-2088	599	3	context	context	NOUN
admet-2088	599	4	,	,	PUNCT
admet-2088	599	5	cordeiro	cordeiro	PROPN
admet-2088	599	6	et	et	PROPN
admet-2088	599	7	al	al	PROPN
admet-2088	599	8	.	.	PUNCT
admet-2088	600	1	[	[	X
admet-2088	600	2	11	11	NUM
admet-2088	600	3	]	]	PUNCT
admet-2088	600	4	developed	develop	VERB
admet-2088	600	5	beeswax	beeswax	NOUN
admet-2088	600	6	-	-	PUNCT
admet-2088	600	7	based	base	VERB
admet-2088	600	8	nps	nps	PROPN
admet-2088	600	9	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	PROPN
admet-2088	600	10	m.	m.	NOUN
admet-2088	600	11	kulkarni	kulkarni	PROPN
admet-2088	600	12	et	et	PROPN
admet-2088	600	13	al	al	PROPN
admet-2088	600	14	.	.	PROPN
admet-2088	600	15	admet	admet	PROPN
admet-2088	600	16	&	&	CCONJ
admet-2088	600	17	dmpk	dmpk	PROPN
admet-2088	600	18	12(1	12(1	PROPN
admet-2088	600	19	)	)	PUNCT
admet-2088	600	20	(	(	PUNCT
admet-2088	600	21	2024	2024	NUM
admet-2088	600	22	)	)	PUNCT
admet-2088	600	23	107	107	NUM
admet-2088	600	24	-	-	SYM
admet-2088	600	25	150	150	NUM
admet-2088	600	26	130	130	NUM
admet-2088	600	27	simultaneously	simultaneously	ADV
admet-2088	600	28	loaded	load	VERB
admet-2088	600	29	with	with	ADP
admet-2088	600	30	a	a	DET
admet-2088	600	31	hydrophobic	hydrophobic	NOUN
admet-2088	600	32	drug	drug	NOUN
admet-2088	600	33	,	,	PUNCT
admet-2088	600	34	4	4	NUM
admet-2088	600	35	-	-	NOUN
admet-2088	600	36	nitrochalcone	nitrochalcone	NOUN
admet-2088	600	37	(	(	PUNCT
admet-2088	600	38	4nc	4nc	ADJ
admet-2088	600	39	)	)	PUNCT
admet-2088	600	40	and	and	CCONJ
admet-2088	600	41	a	a	DET
admet-2088	600	42	hydrophilic	hydrophilic	ADJ
admet-2088	600	43	drug	drug	NOUN
admet-2088	600	44	,	,	PUNCT
admet-2088	600	45	sodium	sodium	NOUN
admet-2088	600	46	diethyldithiocarbamate	diethyldithiocarbamate	NOUN
admet-2088	600	47	(	(	PUNCT
admet-2088	600	48	detc	detc	NOUN
admet-2088	600	49	)	)	PUNCT
admet-2088	600	50	,	,	PUNCT
admet-2088	600	51	for	for	ADP
admet-2088	600	52	the	the	DET
admet-2088	600	53	treatment	treatment	NOUN
admet-2088	600	54	of	of	ADP
admet-2088	600	55	melanoma	melanoma	NOUN
admet-2088	600	56	cells	cell	NOUN
admet-2088	600	57	(	(	PUNCT
admet-2088	600	58	b16f10	b16f10	NOUN
admet-2088	600	59	)	)	PUNCT
admet-2088	600	60	synergistically	synergistically	ADV
admet-2088	600	61	.	.	PUNCT
admet-2088	601	1	this	this	DET
admet-2088	601	2	nanosystem	nanosystem	NOUN
admet-2088	601	3	showed	show	VERB
admet-2088	601	4	higher	high	ADJ
admet-2088	601	5	cytotoxicity	cytotoxicity	NOUN
admet-2088	601	6	towards	towards	ADP
admet-2088	601	7	melanoma	melanoma	NOUN
admet-2088	601	8	cells	cell	NOUN
admet-2088	601	9	compared	compare	VERB
admet-2088	601	10	to	to	ADP
admet-2088	601	11	free	free	ADJ
admet-2088	601	12	drugs	drug	NOUN
admet-2088	601	13	.	.	PUNCT
admet-2088	602	1	in	in	ADP
admet-2088	602	2	addition	addition	NOUN
admet-2088	602	3	,	,	PUNCT
admet-2088	602	4	the	the	DET
admet-2088	602	5	system	system	NOUN
admet-2088	602	6	was	be	AUX
admet-2088	602	7	able	able	ADJ
admet-2088	602	8	to	to	PART
admet-2088	602	9	reduce	reduce	VERB
admet-2088	602	10	the	the	DET
admet-2088	602	11	cell	cell	NOUN
admet-2088	602	12	viability	viability	NOUN
admet-2088	602	13	from	from	ADP
admet-2088	602	14	46	46	NUM
admet-2088	602	15	%	%	NOUN
admet-2088	602	16	for	for	ADP
admet-2088	602	17	detc	detc	NOUN
admet-2088	602	18	-	-	PUNCT
admet-2088	602	19	based	base	VERB
admet-2088	602	20	nps	nps	PROPN
admet-2088	602	21	and	and	CCONJ
admet-2088	602	22	54	54	NUM
admet-2088	602	23	%	%	NOUN
admet-2088	602	24	for	for	ADP
admet-2088	602	25	4nc	4nc	NOUN
admet-2088	602	26	-	-	PUNCT
admet-2088	602	27	based	base	VERB
admet-2088	602	28	nps	nps	PROPN
admet-2088	602	29	to	to	ADP
admet-2088	602	30	64	64	NUM
admet-2088	602	31	%	%	NOUN
admet-2088	602	32	.	.	PUNCT
admet-2088	603	1	moreover	moreover	ADV
admet-2088	603	2	,	,	PUNCT
admet-2088	603	3	the	the	DET
admet-2088	603	4	ic50	ic50	PROPN
admet-2088	603	5	of	of	ADP
admet-2088	603	6	the	the	DET
admet-2088	603	7	two	two	NUM
admet-2088	603	8	drugs	drug	NOUN
admet-2088	603	9	was	be	AUX
admet-2088	603	10	found	find	VERB
admet-2088	603	11	to	to	PART
admet-2088	603	12	be	be	AUX
admet-2088	603	13	lower	low	ADJ
admet-2088	603	14	than	than	ADP
admet-2088	603	15	that	that	PRON
admet-2088	603	16	of	of	ADP
admet-2088	603	17	individual	individual	ADJ
admet-2088	603	18	drugs	drug	NOUN
admet-2088	603	19	when	when	SCONJ
admet-2088	603	20	encapsulated	encapsulate	VERB
admet-2088	603	21	in	in	ADP
admet-2088	603	22	beeswax	beeswax	PROPN
admet-2088	603	23	nps	nps	PROPN
admet-2088	603	24	.	.	PUNCT
admet-2088	604	1	extracellular	extracellular	ADJ
admet-2088	604	2	vesicles	vesicle	NOUN
admet-2088	604	3	exosomes	exosome	NOUN
admet-2088	604	4	exosomes	exosome	NOUN
admet-2088	604	5	are	be	AUX
admet-2088	604	6	one	one	NUM
admet-2088	604	7	type	type	NOUN
admet-2088	604	8	of	of	ADP
admet-2088	604	9	nano	nano	NOUN
admet-2088	604	10	-	-	PUNCT
admet-2088	604	11	sized	sized	ADJ
admet-2088	604	12	(	(	PUNCT
admet-2088	604	13	30	30	NUM
admet-2088	604	14	-	-	SYM
admet-2088	604	15	100	100	NUM
admet-2088	604	16	nm	nm	NOUN
admet-2088	604	17	in	in	ADP
admet-2088	604	18	diameter	diameter	NOUN
admet-2088	604	19	)	)	PUNCT
admet-2088	604	20	lipid	lipid	NOUN
admet-2088	604	21	-	-	PUNCT
admet-2088	604	22	based	base	VERB
admet-2088	604	23	bilayer	bilayer	NOUN
admet-2088	604	24	vesicles	vesicle	NOUN
admet-2088	604	25	[	[	X
admet-2088	604	26	220,221	220,221	NUM
admet-2088	604	27	]	]	PUNCT
admet-2088	604	28	,	,	PUNCT
admet-2088	604	29	secreted	secrete	VERB
admet-2088	604	30	by	by	ADP
admet-2088	604	31	most	most	ADJ
admet-2088	604	32	living	live	VERB
admet-2088	604	33	cells	cell	NOUN
admet-2088	604	34	through	through	ADP
admet-2088	604	35	the	the	DET
admet-2088	604	36	endocytosis	endocytosis	NOUN
admet-2088	604	37	process	process	NOUN
admet-2088	604	38	and	and	CCONJ
admet-2088	604	39	responsible	responsible	ADJ
admet-2088	604	40	for	for	ADP
admet-2088	604	41	cell	cell	NOUN
admet-2088	604	42	-	-	PUNCT
admet-2088	604	43	cell	cell	NOUN
admet-2088	604	44	communications	communication	NOUN
admet-2088	604	45	[	[	X
admet-2088	604	46	222	222	NUM
admet-2088	604	47	]	]	PUNCT
admet-2088	604	48	.	.	PUNCT
admet-2088	605	1	primarily	primarily	ADV
admet-2088	605	2	,	,	PUNCT
admet-2088	605	3	exosomes	exosome	NOUN
admet-2088	605	4	are	be	AUX
admet-2088	605	5	employed	employ	VERB
admet-2088	605	6	as	as	ADP
admet-2088	605	7	biomarkers	biomarker	NOUN
admet-2088	605	8	for	for	ADP
admet-2088	605	9	diagnostics	diagnostic	NOUN
admet-2088	605	10	and	and	CCONJ
admet-2088	605	11	potential	potential	ADJ
admet-2088	605	12	natural	natural	ADJ
admet-2088	605	13	drug	drug	NOUN
admet-2088	605	14	delivery	delivery	NOUN
admet-2088	605	15	vehicles	vehicle	NOUN
admet-2088	605	16	.	.	PUNCT
admet-2088	606	1	as	as	ADP
admet-2088	606	2	a	a	DET
admet-2088	606	3	drug	drug	NOUN
admet-2088	606	4	carrier	carrier	NOUN
admet-2088	606	5	,	,	PUNCT
admet-2088	606	6	exosomes	exosome	NOUN
admet-2088	606	7	have	have	VERB
admet-2088	606	8	many	many	ADJ
admet-2088	606	9	advantages	advantage	NOUN
admet-2088	606	10	,	,	PUNCT
admet-2088	606	11	such	such	ADJ
admet-2088	606	12	as	as	ADP
admet-2088	606	13	the	the	DET
admet-2088	606	14	ability	ability	NOUN
admet-2088	606	15	to	to	PART
admet-2088	606	16	penetrate	penetrate	VERB
admet-2088	606	17	across	across	ADP
admet-2088	606	18	a	a	DET
admet-2088	606	19	variety	variety	NOUN
admet-2088	606	20	of	of	ADP
admet-2088	606	21	biological	biological	ADJ
admet-2088	606	22	barriers	barrier	NOUN
admet-2088	606	23	,	,	PUNCT
admet-2088	606	24	including	include	VERB
admet-2088	606	25	blood	blood	NOUN
admet-2088	606	26	-	-	PUNCT
admet-2088	606	27	brain	brain	NOUN
admet-2088	606	28	-	-	PUNCT
admet-2088	606	29	barrier	barrier	NOUN
admet-2088	606	30	(	(	PUNCT
admet-2088	606	31	bbb	bbb	NOUN
admet-2088	606	32	)	)	PUNCT
admet-2088	606	33	,	,	PUNCT
admet-2088	606	34	natural	natural	ADJ
admet-2088	606	35	targeting	targeting	NOUN
admet-2088	606	36	capability	capability	NOUN
admet-2088	606	37	,	,	PUNCT
admet-2088	606	38	biocompatible	biocompatible	ADJ
admet-2088	606	39	,	,	PUNCT
admet-2088	606	40	less	less	ADV
admet-2088	606	41	immunogenic	immunogenic	ADJ
admet-2088	606	42	compared	compare	VERB
admet-2088	606	43	to	to	ADP
admet-2088	606	44	artificial	artificial	ADJ
admet-2088	606	45	nanocarriers	nanocarrier	NOUN
admet-2088	606	46	,	,	PUNCT
admet-2088	606	47	high	high	ADJ
admet-2088	606	48	stability	stability	NOUN
admet-2088	606	49	and	and	CCONJ
admet-2088	606	50	ability	ability	NOUN
admet-2088	606	51	to	to	PART
admet-2088	606	52	deliver	deliver	VERB
admet-2088	606	53	both	both	DET
admet-2088	606	54	large	large	ADJ
admet-2088	606	55	biological	biological	ADJ
admet-2088	606	56	molecules	molecule	NOUN
admet-2088	606	57	such	such	ADJ
admet-2088	606	58	as	as	ADP
admet-2088	606	59	genetic	genetic	ADJ
admet-2088	606	60	materials	material	NOUN
admet-2088	606	61	,	,	PUNCT
admet-2088	606	62	various	various	ADJ
admet-2088	606	63	protein	protein	NOUN
admet-2088	606	64	and	and	CCONJ
admet-2088	606	65	lipids	lipids	ADJ
admet-2088	606	66	and	and	CCONJ
admet-2088	606	67	small	small	ADJ
admet-2088	606	68	active	active	ADJ
admet-2088	606	69	drug	drug	NOUN
admet-2088	606	70	molecules	molecule	NOUN
admet-2088	606	71	[	[	X
admet-2088	606	72	223	223	NUM
admet-2088	606	73	]	]	PUNCT
admet-2088	606	74	.	.	PUNCT
admet-2088	607	1	in	in	ADP
admet-2088	607	2	addition	addition	NOUN
admet-2088	607	3	,	,	PUNCT
admet-2088	607	4	exosomes	exosome	NOUN
admet-2088	607	5	can	can	AUX
admet-2088	607	6	take	take	VERB
admet-2088	607	7	advantage	advantage	NOUN
admet-2088	607	8	of	of	ADP
admet-2088	607	9	receptor	receptor	NOUN
admet-2088	607	10	-	-	PUNCT
admet-2088	607	11	ligand	ligand	NOUN
admet-2088	607	12	interaction	interaction	NOUN
admet-2088	607	13	to	to	PART
admet-2088	607	14	enter	enter	VERB
admet-2088	607	15	into	into	ADP
admet-2088	607	16	the	the	DET
admet-2088	607	17	cytosol	cytosol	NOUN
admet-2088	607	18	,	,	PUNCT
admet-2088	607	19	whereas	whereas	SCONJ
admet-2088	607	20	synthetic	synthetic	ADJ
admet-2088	607	21	lipid	lipid	NOUN
admet-2088	607	22	-	-	PUNCT
admet-2088	607	23	based	base	VERB
admet-2088	607	24	nps	nps	PROPN
admet-2088	607	25	have	have	VERB
admet-2088	607	26	the	the	DET
admet-2088	607	27	tendency	tendency	NOUN
admet-2088	607	28	to	to	PART
admet-2088	607	29	accumulate	accumulate	VERB
admet-2088	607	30	on	on	ADP
admet-2088	607	31	cell	cell	NOUN
admet-2088	607	32	membranes	membrane	NOUN
admet-2088	607	33	[	[	X
admet-2088	607	34	224	224	NUM
admet-2088	607	35	]	]	PUNCT
admet-2088	607	36	.	.	PUNCT
admet-2088	608	1	after	after	ADP
admet-2088	608	2	reaching	reach	VERB
admet-2088	608	3	the	the	DET
admet-2088	608	4	cytosol	cytosol	NOUN
admet-2088	608	5	of	of	ADP
admet-2088	608	6	the	the	DET
admet-2088	608	7	cell	cell	NOUN
admet-2088	608	8	,	,	PUNCT
admet-2088	608	9	exosomes	exosome	VERB
admet-2088	608	10	fuse	fuse	NOUN
admet-2088	608	11	with	with	ADP
admet-2088	608	12	the	the	DET
admet-2088	608	13	endosomes	endosome	NOUN
admet-2088	608	14	and	and	CCONJ
admet-2088	608	15	deliver	deliver	VERB
admet-2088	608	16	the	the	DET
admet-2088	608	17	loaded	load	VERB
admet-2088	608	18	drugs	drug	NOUN
admet-2088	608	19	.	.	PUNCT
admet-2088	609	1	thus	thus	ADV
admet-2088	609	2	,	,	PUNCT
admet-2088	609	3	exosomes	exosome	NOUN
admet-2088	609	4	have	have	VERB
admet-2088	609	5	the	the	DET
admet-2088	609	6	ability	ability	NOUN
admet-2088	609	7	to	to	PART
admet-2088	609	8	improve	improve	VERB
admet-2088	609	9	drug	drug	NOUN
admet-2088	609	10	delivery	delivery	NOUN
admet-2088	609	11	efficiency	efficiency	NOUN
admet-2088	609	12	and	and	CCONJ
admet-2088	609	13	targeting	target	VERB
admet-2088	609	14	[	[	X
admet-2088	609	15	225	225	NUM
admet-2088	609	16	]	]	PUNCT
admet-2088	609	17	.	.	PUNCT
admet-2088	610	1	however	however	ADV
admet-2088	610	2	,	,	PUNCT
admet-2088	610	3	exosomes	exosome	VERB
admet-2088	610	4	capacity	capacity	NOUN
admet-2088	610	5	to	to	PART
admet-2088	610	6	deliver	deliver	VERB
admet-2088	610	7	a	a	DET
admet-2088	610	8	significant	significant	ADJ
admet-2088	610	9	amount	amount	NOUN
admet-2088	610	10	of	of	ADP
admet-2088	610	11	active	active	ADJ
admet-2088	610	12	ingredients	ingredient	NOUN
admet-2088	610	13	is	be	AUX
admet-2088	610	14	restricted	restrict	VERB
admet-2088	610	15	and	and	CCONJ
admet-2088	610	16	the	the	DET
admet-2088	610	17	separation	separation	NOUN
admet-2088	610	18	with	with	ADP
admet-2088	610	19	high	high	ADJ
admet-2088	610	20	purity	purity	NOUN
admet-2088	610	21	is	be	AUX
admet-2088	610	22	labour	labour	NOUN
admet-2088	610	23	-	-	PUNCT
admet-2088	610	24	intensive	intensive	ADJ
admet-2088	610	25	and	and	CCONJ
admet-2088	610	26	time	time	NOUN
admet-2088	610	27	-	-	PUNCT
admet-2088	610	28	consuming	consume	VERB
admet-2088	610	29	.	.	PUNCT
admet-2088	611	1	thus	thus	ADV
admet-2088	611	2	,	,	PUNCT
admet-2088	611	3	genetic	genetic	ADJ
admet-2088	611	4	engineering	engineering	NOUN
admet-2088	611	5	,	,	PUNCT
admet-2088	611	6	followed	follow	VERB
admet-2088	611	7	by	by	ADP
admet-2088	611	8	the	the	DET
admet-2088	611	9	cell	cell	NOUN
admet-2088	611	10	culture	culture	NOUN
admet-2088	611	11	method	method	NOUN
admet-2088	611	12	,	,	PUNCT
admet-2088	611	13	has	have	AUX
admet-2088	611	14	been	be	AUX
admet-2088	611	15	adopted	adopt	VERB
admet-2088	611	16	for	for	ADP
admet-2088	611	17	the	the	DET
admet-2088	611	18	production	production	NOUN
admet-2088	611	19	of	of	ADP
admet-2088	611	20	large	large	ADJ
admet-2088	611	21	amounts	amount	NOUN
admet-2088	611	22	of	of	ADP
admet-2088	611	23	exosomes	exosome	NOUN
admet-2088	611	24	.	.	PUNCT
admet-2088	612	1	the	the	DET
admet-2088	612	2	drug	drug	NOUN
admet-2088	612	3	loading	loading	NOUN
admet-2088	612	4	into	into	ADP
admet-2088	612	5	exosomes	exosome	NOUN
admet-2088	612	6	is	be	AUX
admet-2088	612	7	a	a	DET
admet-2088	612	8	crucial	crucial	ADJ
admet-2088	612	9	step	step	NOUN
admet-2088	612	10	in	in	ADP
admet-2088	612	11	drug	drug	NOUN
admet-2088	612	12	delivery	delivery	NOUN
admet-2088	612	13	,	,	PUNCT
admet-2088	612	14	which	which	PRON
admet-2088	612	15	can	can	AUX
admet-2088	612	16	be	be	AUX
admet-2088	612	17	performed	perform	VERB
admet-2088	612	18	either	either	CCONJ
admet-2088	612	19	endogenously	endogenously	ADV
admet-2088	612	20	or	or	CCONJ
admet-2088	612	21	exogenously	exogenously	ADV
admet-2088	612	22	.	.	PUNCT
admet-2088	613	1	for	for	ADP
admet-2088	613	2	the	the	DET
admet-2088	613	3	endogenous	endogenous	ADJ
admet-2088	613	4	approach	approach	NOUN
admet-2088	613	5	,	,	PUNCT
admet-2088	613	6	the	the	DET
admet-2088	613	7	exosomes	exosome	NOUN
admet-2088	613	8	are	be	AUX
admet-2088	613	9	genetically	genetically	ADV
admet-2088	613	10	modified	modify	VERB
admet-2088	613	11	to	to	PART
admet-2088	613	12	increase	increase	VERB
admet-2088	613	13	drug	drug	NOUN
admet-2088	613	14	-	-	PUNCT
admet-2088	613	15	containing	contain	VERB
admet-2088	613	16	exosome	exosome	NOUN
admet-2088	613	17	production	production	NOUN
admet-2088	613	18	,	,	PUNCT
admet-2088	613	19	whereas	whereas	SCONJ
admet-2088	613	20	the	the	DET
admet-2088	613	21	exogenous	exogenous	ADJ
admet-2088	613	22	method	method	NOUN
admet-2088	613	23	involves	involve	VERB
admet-2088	613	24	loading	load	VERB
admet-2088	613	25	drugs	drug	NOUN
admet-2088	613	26	into	into	ADP
admet-2088	613	27	them	they	PRON
admet-2088	613	28	using	use	VERB
admet-2088	613	29	encapsulation	encapsulation	NOUN
admet-2088	613	30	techniques	technique	NOUN
admet-2088	613	31	such	such	ADJ
admet-2088	613	32	as	as	ADP
admet-2088	613	33	sonication	sonication	NOUN
admet-2088	613	34	,	,	PUNCT
admet-2088	613	35	electroporation	electroporation	NOUN
admet-2088	613	36	,	,	PUNCT
admet-2088	613	37	incubation	incubation	NOUN
admet-2088	613	38	and	and	CCONJ
admet-2088	613	39	extrusion	extrusion	NOUN
admet-2088	614	1	[	[	X
admet-2088	614	2	226	226	NUM
admet-2088	614	3	-	-	SYM
admet-2088	614	4	228	228	NUM
admet-2088	614	5	]	]	PUNCT
admet-2088	614	6	.	.	PUNCT
admet-2088	615	1	most	most	ADV
admet-2088	615	2	recently	recently	ADV
admet-2088	615	3	,	,	PUNCT
admet-2088	615	4	feng	feng	PROPN
admet-2088	615	5	et	et	PROPN
admet-2088	615	6	al	al	PROPN
admet-2088	615	7	.	.	PUNCT
admet-2088	616	1	[	[	X
admet-2088	616	2	229	229	NUM
admet-2088	616	3	]	]	PUNCT
admet-2088	616	4	developed	develop	VERB
admet-2088	616	5	a	a	DET
admet-2088	616	6	coordination	coordination	NOUN
admet-2088	616	7	-	-	PUNCT
admet-2088	616	8	driven	drive	VERB
admet-2088	616	9	assembly	assembly	NOUN
admet-2088	616	10	of	of	ADP
admet-2088	616	11	ir(iii	ir(iii	NOUN
admet-2088	616	12	)	)	PUNCT
admet-2088	616	13	photosensitizer	photosensitizer	NOUN
admet-2088	616	14	with	with	ADP
admet-2088	616	15	fe(iii	fe(iii	NOUN
admet-2088	616	16	)	)	PUNCT
admet-2088	616	17	ions	ion	NOUN
admet-2088	616	18	into	into	ADP
admet-2088	616	19	nanopolymers	nanopolymer	NOUN
admet-2088	616	20	(	(	PUNCT
admet-2088	616	21	ir	ir	PROPN
admet-2088	616	22	-	-	PUNCT
admet-2088	616	23	fe	fe	X
admet-2088	616	24	nps	nps	PROPN
admet-2088	616	25	)	)	PUNCT
admet-2088	616	26	for	for	ADP
admet-2088	616	27	synergistic	synergistic	ADJ
admet-2088	616	28	pdt	pdt	NOUN
admet-2088	616	29	and	and	CCONJ
admet-2088	616	30	cdt	cdt	PROPN
admet-2088	616	31	therapy	therapy	NOUN
admet-2088	616	32	against	against	ADP
admet-2088	616	33	melanoma	melanoma	NOUN
admet-2088	616	34	.	.	PUNCT
admet-2088	617	1	further	far	ADV
admet-2088	617	2	,	,	PUNCT
admet-2088	617	3	these	these	DET
admet-2088	617	4	nps	nps	PROPN
admet-2088	617	5	were	be	AUX
admet-2088	617	6	camouflaged	camouflage	VERB
admet-2088	617	7	with	with	ADP
admet-2088	617	8	melanoma	melanoma	NOUN
admet-2088	617	9	exosomes	exosome	NOUN
admet-2088	617	10	to	to	PART
admet-2088	617	11	form	form	VERB
admet-2088	617	12	ir	ir	NOUN
admet-2088	617	13	-	-	NOUN
admet-2088	617	14	fe@exo	fe@exo	NOUN
admet-2088	617	15	to	to	PART
admet-2088	617	16	further	further	VERB
admet-2088	617	17	their	their	PRON
admet-2088	617	18	cancer	cancer	NOUN
admet-2088	617	19	selectivity	selectivity	NOUN
admet-2088	617	20	and	and	CCONJ
admet-2088	617	21	stability	stability	NOUN
admet-2088	617	22	.	.	PUNCT
admet-2088	618	1	upon	upon	SCONJ
admet-2088	618	2	exposure	exposure	NOUN
admet-2088	618	3	to	to	ADP
admet-2088	618	4	two	two	NUM
admet-2088	618	5	-	-	PUNCT
admet-2088	618	6	photon	photon	NOUN
admet-2088	618	7	irradiation	irradiation	NOUN
admet-2088	618	8	,	,	PUNCT
admet-2088	618	9	ir(iii	ir(iii	NOUN
admet-2088	618	10	)	)	PUNCT
admet-2088	618	11	complexes	complex	NOUN
admet-2088	618	12	generate	generate	VERB
admet-2088	618	13	a	a	DET
admet-2088	618	14	combination	combination	NOUN
admet-2088	618	15	of	of	ADP
admet-2088	618	16	singlet	singlet	ADJ
admet-2088	618	17	oxygen	oxygen	NOUN
admet-2088	618	18	and	and	CCONJ
admet-2088	618	19	superoxide	superoxide	NOUN
admet-2088	618	20	anion	anion	NOUN
admet-2088	618	21	radicals	radical	NOUN
admet-2088	618	22	that	that	PRON
admet-2088	618	23	have	have	VERB
admet-2088	618	24	the	the	DET
admet-2088	618	25	capability	capability	NOUN
admet-2088	618	26	to	to	PART
admet-2088	618	27	induce	induce	VERB
admet-2088	618	28	cell	cell	NOUN
admet-2088	618	29	death	death	NOUN
admet-2088	618	30	through	through	ADP
admet-2088	618	31	autophagy	autophagy	NOUN
admet-2088	618	32	and	and	CCONJ
admet-2088	618	33	apoptosis	apoptosis	NOUN
admet-2088	618	34	.	.	PUNCT
admet-2088	619	1	on	on	ADP
admet-2088	619	2	the	the	DET
admet-2088	619	3	other	other	ADJ
admet-2088	619	4	hand	hand	NOUN
admet-2088	619	5	,	,	PUNCT
admet-2088	619	6	fe(iii	fe(iii	NOUN
admet-2088	619	7	)	)	PUNCT
admet-2088	619	8	ions	ion	NOUN
admet-2088	619	9	are	be	AUX
admet-2088	619	10	involved	involve	VERB
admet-2088	619	11	in	in	ADP
admet-2088	619	12	the	the	DET
admet-2088	619	13	depletion	depletion	NOUN
admet-2088	619	14	of	of	ADP
admet-2088	619	15	glutathione	glutathione	NOUN
admet-2088	619	16	,	,	PUNCT
admet-2088	619	17	the	the	DET
admet-2088	619	18	generation	generation	NOUN
admet-2088	619	19	of	of	ADP
admet-2088	619	20	lipid	lipid	ADJ
admet-2088	619	21	peroxide	peroxide	NOUN
admet-2088	619	22	and	and	CCONJ
admet-2088	619	23	the	the	DET
admet-2088	619	24	lowering	lowering	NOUN
admet-2088	619	25	of	of	ADP
admet-2088	619	26	gpx4	gpx4	NOUN
admet-2088	619	27	levels	level	NOUN
admet-2088	619	28	within	within	ADP
admet-2088	619	29	the	the	DET
admet-2088	619	30	cancer	cancer	NOUN
admet-2088	619	31	cells	cell	NOUN
admet-2088	619	32	,	,	PUNCT
admet-2088	619	33	thereby	thereby	ADV
admet-2088	619	34	the	the	DET
admet-2088	619	35	induction	induction	NOUN
admet-2088	619	36	of	of	ADP
admet-2088	619	37	ferroptosis	ferroptosis	NOUN
admet-2088	619	38	.	.	PUNCT
admet-2088	620	1	the	the	DET
admet-2088	620	2	obtained	obtain	VERB
admet-2088	620	3	exosomes	exosome	NOUN
admet-2088	620	4	demonstrated	demonstrate	VERB
admet-2088	620	5	enhanced	enhanced	ADJ
admet-2088	620	6	blood	blood	NOUN
admet-2088	620	7	circulation	circulation	NOUN
admet-2088	620	8	and	and	CCONJ
admet-2088	620	9	high	high	ADJ
admet-2088	620	10	tumour	tumour	NOUN
admet-2088	620	11	accumulation	accumulation	NOUN
admet-2088	620	12	inside	inside	ADP
admet-2088	620	13	a	a	DET
admet-2088	620	14	melanoma	melanoma	PROPN
admet-2088	620	15	xenograft	xenograft	PROPN
admet-2088	620	16	mouse	mouse	PROPN
admet-2088	620	17	model	model	NOUN
admet-2088	620	18	.	.	PUNCT
admet-2088	621	1	in	in	ADP
admet-2088	621	2	addition	addition	NOUN
admet-2088	621	3	,	,	PUNCT
admet-2088	621	4	melanoma	melanoma	NOUN
admet-2088	621	5	tumours	tumour	NOUN
admet-2088	621	6	were	be	AUX
admet-2088	621	7	fully	fully	ADV
admet-2088	621	8	eradicated	eradicate	VERB
admet-2088	621	9	with	with	ADP
admet-2088	621	10	a	a	DET
admet-2088	621	11	single	single	ADJ
admet-2088	621	12	treatment	treatment	NOUN
admet-2088	621	13	of	of	ADP
admet-2088	621	14	prepared	prepared	ADJ
admet-2088	621	15	exosomes	exosome	NOUN
admet-2088	621	16	intravenously	intravenously	ADV
admet-2088	621	17	followed	follow	VERB
admet-2088	621	18	by	by	ADP
admet-2088	621	19	two	two	NUM
admet-2088	621	20	-	-	PUNCT
admet-2088	621	21	photon	photon	NOUN
admet-2088	621	22	irradiation	irradiation	NOUN
admet-2088	621	23	.	.	PUNCT
admet-2088	622	1	furthermore	furthermore	ADV
admet-2088	622	2	,	,	PUNCT
admet-2088	622	3	these	these	DET
admet-2088	622	4	exosomes	exosome	NOUN
admet-2088	622	5	prevent	prevent	VERB
admet-2088	622	6	the	the	DET
admet-2088	622	7	formation	formation	NOUN
admet-2088	622	8	of	of	ADP
admet-2088	622	9	lung	lung	NOUN
admet-2088	622	10	metastasis	metastasis	NOUN
admet-2088	622	11	inside	inside	ADP
admet-2088	622	12	the	the	DET
admet-2088	622	13	mouse	mouse	NOUN
admet-2088	622	14	model	model	NOUN
admet-2088	622	15	.	.	PUNCT
admet-2088	623	1	gene	gene	NOUN
admet-2088	623	2	therapy	therapy	NOUN
admet-2088	623	3	for	for	ADP
admet-2088	623	4	melanoma	melanoma	NOUN
admet-2088	623	5	the	the	DET
admet-2088	623	6	fast	fast	ADJ
admet-2088	623	7	progress	progress	NOUN
admet-2088	623	8	in	in	ADP
admet-2088	623	9	science	science	NOUN
admet-2088	623	10	in	in	ADP
admet-2088	623	11	the	the	DET
admet-2088	623	12	21st	21st	ADJ
admet-2088	623	13	century	century	NOUN
admet-2088	623	14	made	make	VERB
admet-2088	623	15	it	it	PRON
admet-2088	623	16	realise	realise	VERB
admet-2088	623	17	that	that	SCONJ
admet-2088	623	18	gene	gene	NOUN
admet-2088	623	19	delivery	delivery	NOUN
admet-2088	623	20	for	for	ADP
admet-2088	623	21	various	various	ADJ
admet-2088	623	22	genetic	genetic	ADJ
admet-2088	623	23	diseases	disease	NOUN
admet-2088	623	24	is	be	AUX
admet-2088	623	25	achievable	achievable	ADJ
admet-2088	623	26	.	.	PUNCT
admet-2088	624	1	however	however	ADV
admet-2088	624	2	,	,	PUNCT
admet-2088	624	3	numerous	numerous	ADJ
admet-2088	624	4	challenges	challenge	NOUN
admet-2088	624	5	are	be	AUX
admet-2088	624	6	involved	involve	VERB
admet-2088	624	7	when	when	SCONJ
admet-2088	624	8	naked	naked	ADJ
admet-2088	624	9	nucleic	nucleic	ADJ
admet-2088	624	10	acids	acid	NOUN
admet-2088	624	11	are	be	AUX
admet-2088	624	12	subjected	subject	VERB
admet-2088	624	13	to	to	ADP
admet-2088	624	14	systemic	systemic	ADJ
admet-2088	624	15	administration	administration	NOUN
admet-2088	624	16	,	,	PUNCT
admet-2088	624	17	including	include	VERB
admet-2088	624	18	enzymatic	enzymatic	ADJ
admet-2088	624	19	degradation	degradation	NOUN
admet-2088	624	20	and	and	CCONJ
admet-2088	624	21	non	non	ADJ
admet-2088	624	22	-	-	ADJ
admet-2088	624	23	specific	specific	ADJ
admet-2088	624	24	delivery	delivery	NOUN
admet-2088	624	25	.	.	PUNCT
admet-2088	625	1	therefore	therefore	ADV
admet-2088	625	2	,	,	PUNCT
admet-2088	625	3	there	there	PRON
admet-2088	625	4	is	be	VERB
admet-2088	625	5	an	an	DET
admet-2088	625	6	urgent	urgent	ADJ
admet-2088	625	7	need	need	NOUN
admet-2088	625	8	to	to	PART
admet-2088	625	9	explore	explore	VERB
admet-2088	625	10	and	and	CCONJ
admet-2088	625	11	develop	develop	VERB
admet-2088	625	12	smart	smart	ADJ
admet-2088	625	13	nanocarriers	nanocarrier	NOUN
admet-2088	625	14	that	that	PRON
admet-2088	625	15	will	will	AUX
admet-2088	625	16	be	be	AUX
admet-2088	625	17	able	able	ADJ
admet-2088	625	18	to	to	PART
admet-2088	625	19	load	load	VERB
admet-2088	625	20	the	the	DET
admet-2088	625	21	genetic	genetic	ADJ
admet-2088	625	22	material	material	NOUN
admet-2088	625	23	followed	follow	VERB
admet-2088	625	24	by	by	ADP
admet-2088	625	25	their	their	PRON
admet-2088	625	26	passage	passage	NOUN
admet-2088	625	27	through	through	ADP
admet-2088	625	28	various	various	ADJ
admet-2088	625	29	cellular	cellular	ADJ
admet-2088	625	30	barriers	barrier	NOUN
admet-2088	625	31	and	and	CCONJ
admet-2088	625	32	release	release	VERB
admet-2088	625	33	them	they	PRON
admet-2088	625	34	into	into	ADP
admet-2088	625	35	the	the	DET
admet-2088	625	36	cell	cell	NOUN
admet-2088	625	37	nucleus	nucleus	NOUN
admet-2088	625	38	or	or	CCONJ
admet-2088	625	39	surrounding	surround	VERB
admet-2088	625	40	admet	admet	PROPN
admet-2088	625	41	&	&	CCONJ
admet-2088	625	42	dmpk	dmpk	PROPN
admet-2088	625	43	12(1	12(1	PROPN
admet-2088	625	44	)	)	PUNCT
admet-2088	625	45	(	(	PUNCT
admet-2088	625	46	2024	2024	NUM
admet-2088	625	47	)	)	PUNCT
admet-2088	625	48	107	107	NUM
admet-2088	625	49	-	-	SYM
admet-2088	625	50	150	150	NUM
admet-2088	625	51	nanomaterial	nanomaterial	NOUN
admet-2088	625	52	-	-	PUNCT
admet-2088	625	53	based	base	VERB
admet-2088	625	54	drug	drug	NOUN
admet-2088	625	55	delivery	delivery	NOUN
admet-2088	625	56	systems	system	NOUN
admet-2088	625	57	for	for	ADP
admet-2088	625	58	melanoma	melanoma	NOUN
admet-2088	625	59	therapy	therapy	NOUN
admet-2088	625	60	doi	doi	NOUN
admet-2088	625	61	:	:	PUNCT
admet-2088	625	62	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	PRON
admet-2088	625	63	131	131	NUM
admet-2088	625	64	compartment	compartment	NOUN
admet-2088	625	65	successfully	successfully	ADV
admet-2088	625	66	[	[	X
admet-2088	625	67	230,231	230,231	NUM
admet-2088	625	68	]	]	PUNCT
admet-2088	625	69	.	.	PUNCT
admet-2088	626	1	in	in	ADP
admet-2088	626	2	this	this	DET
admet-2088	626	3	regard	regard	NOUN
admet-2088	626	4	,	,	PUNCT
admet-2088	626	5	two	two	NUM
admet-2088	626	6	approaches	approach	NOUN
admet-2088	626	7	,	,	PUNCT
admet-2088	626	8	such	such	ADJ
admet-2088	626	9	as	as	ADP
admet-2088	626	10	filomicelle	filomicelle	NOUN
admet-2088	626	11	and	and	CCONJ
admet-2088	626	12	nanoworm	nanoworm	NOUN
admet-2088	626	13	ironoxide	ironoxide	ADJ
admet-2088	626	14	particles	particle	NOUN
admet-2088	626	15	,	,	PUNCT
admet-2088	626	16	were	be	AUX
admet-2088	626	17	successfully	successfully	ADV
admet-2088	626	18	applied	apply	VERB
admet-2088	626	19	for	for	ADP
admet-2088	626	20	the	the	DET
admet-2088	626	21	delivery	delivery	NOUN
admet-2088	626	22	of	of	ADP
admet-2088	626	23	sirna	sirna	PROPN
admet-2088	626	24	.	.	PUNCT
admet-2088	627	1	in	in	ADP
admet-2088	627	2	one	one	NUM
admet-2088	627	3	investigation	investigation	NOUN
admet-2088	627	4	,	,	PUNCT
admet-2088	627	5	wang	wang	PROPN
admet-2088	627	6	et	et	PROPN
admet-2088	627	7	al	al	PROPN
admet-2088	627	8	.	.	PUNCT
admet-2088	628	1	[	[	X
admet-2088	628	2	232	232	NUM
admet-2088	628	3	]	]	PUNCT
admet-2088	628	4	employed	employ	VERB
admet-2088	628	5	a	a	DET
admet-2088	628	6	novel	novel	ADJ
admet-2088	628	7	type	type	NOUN
admet-2088	628	8	of	of	ADP
admet-2088	628	9	nanoworm	nanoworm	NOUN
admet-2088	628	10	,	,	PUNCT
admet-2088	628	11	biomimetic	biomimetic	ADJ
admet-2088	628	12	nanoerythrocytes	nanoerythrocyte	NOUN
admet-2088	628	13	,	,	PUNCT
admet-2088	628	14	for	for	ADP
admet-2088	628	15	sirna	sirna	PROPN
admet-2088	628	16	delivery	delivery	NOUN
admet-2088	628	17	for	for	ADP
admet-2088	628	18	the	the	DET
admet-2088	628	19	treatment	treatment	NOUN
admet-2088	628	20	of	of	ADP
admet-2088	628	21	melanoma	melanoma	NOUN
admet-2088	628	22	.	.	PUNCT
admet-2088	629	1	this	this	DET
admet-2088	629	2	approach	approach	NOUN
admet-2088	629	3	involves	involve	VERB
admet-2088	629	4	red	red	ADJ
admet-2088	629	5	blood	blood	NOUN
admet-2088	629	6	cell	cell	NOUN
admet-2088	629	7	(	(	PUNCT
admet-2088	629	8	rbc	rbc	PROPN
admet-2088	629	9	)	)	PUNCT
admet-2088	629	10	membrane	membrane	NOUN
admet-2088	629	11	clocking	clocking	NOUN
admet-2088	629	12	of	of	ADP
admet-2088	629	13	charge	charge	NOUN
admet-2088	629	14	-	-	PUNCT
admet-2088	629	15	reversible	reversible	ADJ
admet-2088	629	16	polyplexes	polyplexe	NOUN
admet-2088	629	17	of	of	ADP
admet-2088	629	18	sirna	sirna	PROPN
admet-2088	629	19	and	and	CCONJ
admet-2088	629	20	polycation	polycation	NOUN
admet-2088	629	21	.	.	PUNCT
admet-2088	630	1	here	here	ADV
admet-2088	630	2	,	,	PUNCT
admet-2088	630	3	the	the	DET
admet-2088	630	4	clocking	clocking	NOUN
admet-2088	630	5	of	of	ADP
admet-2088	630	6	the	the	DET
admet-2088	630	7	rbc	rbc	PROPN
admet-2088	630	8	membrane	membrane	NOUN
admet-2088	630	9	protects	protect	VERB
admet-2088	630	10	sirna	sirna	PROPN
admet-2088	630	11	from	from	ADP
admet-2088	630	12	degradation	degradation	NOUN
admet-2088	630	13	by	by	ADP
admet-2088	630	14	the	the	DET
admet-2088	630	15	rnase	rnase	PROPN
admet-2088	630	16	enzyme	enzyme	NOUN
admet-2088	630	17	.	.	PUNCT
admet-2088	631	1	this	this	DET
admet-2088	631	2	rbc	rbc	PROPN
admet-2088	631	3	-	-	ADJ
admet-2088	631	4	reversible	reversible	ADJ
admet-2088	631	5	polyplex	polyplex	NOUN
admet-2088	631	6	(	(	PUNCT
admet-2088	631	7	rp	rp	NOUN
admet-2088	631	8	)	)	PUNCT
admet-2088	631	9	not	not	PART
admet-2088	631	10	only	only	ADV
admet-2088	631	11	increased	increase	VERB
admet-2088	631	12	the	the	DET
admet-2088	631	13	blood	blood	NOUN
admet-2088	631	14	circulation	circulation	NOUN
admet-2088	631	15	time	time	NOUN
admet-2088	631	16	compared	compare	VERB
admet-2088	631	17	to	to	ADP
admet-2088	631	18	negatively	negatively	ADV
admet-2088	631	19	and	and	CCONJ
admet-2088	631	20	positively	positively	ADV
admet-2088	631	21	charged	charge	VERB
admet-2088	631	22	bovine	bovine	NOUN
admet-2088	631	23	serum	serum	NOUN
admet-2088	631	24	albumin	albumin	NOUN
admet-2088	631	25	spheres	sphere	NOUN
admet-2088	631	26	but	but	CCONJ
admet-2088	631	27	was	be	AUX
admet-2088	631	28	also	also	ADV
admet-2088	631	29	capable	capable	ADJ
admet-2088	631	30	of	of	ADP
admet-2088	631	31	escaping	escape	VERB
admet-2088	631	32	from	from	ADP
admet-2088	631	33	late	late	ADJ
admet-2088	631	34	endosomes	endosome	NOUN
admet-2088	631	35	/	/	SYM
admet-2088	631	36	lysosomes	lysosome	NOUN
admet-2088	631	37	for	for	ADP
admet-2088	631	38	the	the	DET
admet-2088	631	39	effective	effective	ADJ
admet-2088	631	40	transfection	transfection	NOUN
admet-2088	631	41	of	of	ADP
admet-2088	631	42	gene	gene	NOUN
admet-2088	631	43	knockdown	knockdown	NOUN
admet-2088	631	44	.	.	PUNCT
admet-2088	632	1	due	due	ADP
admet-2088	632	2	to	to	ADP
admet-2088	632	3	exceptional	exceptional	ADJ
admet-2088	632	4	biocompatibility	biocompatibility	NOUN
admet-2088	632	5	and	and	CCONJ
admet-2088	632	6	active	active	ADJ
admet-2088	632	7	targeting	targeting	NOUN
admet-2088	632	8	(	(	PUNCT
admet-2088	632	9	cyclic	cyclic	NOUN
admet-2088	632	10	arg	arg	NOUN
admet-2088	632	11	-	-	PUNCT
admet-2088	632	12	gly	gly	NOUN
admet-2088	632	13	-	-	PUNCT
admet-2088	632	14	asp	asp	NOUN
admet-2088	632	15	,	,	PUNCT
admet-2088	632	16	crgd	crgd	NOUN
admet-2088	632	17	)	)	PUNCT
admet-2088	632	18	,	,	PUNCT
admet-2088	632	19	rgdrbc	rgdrbc	VERB
admet-2088	632	20	-	-	PUNCT
admet-2088	632	21	rp	rp	NOUN
admet-2088	632	22	demonstrated	demonstrate	VERB
admet-2088	632	23	a	a	DET
admet-2088	632	24	superior	superior	ADJ
admet-2088	632	25	anti	anti	ADJ
admet-2088	632	26	-	-	ADJ
admet-2088	632	27	melanoma	melanoma	ADJ
admet-2088	632	28	effect	effect	NOUN
admet-2088	632	29	in	in	ADP
admet-2088	632	30	an	an	DET
admet-2088	632	31	animal	animal	NOUN
admet-2088	632	32	model	model	NOUN
admet-2088	632	33	after	after	ADP
admet-2088	632	34	two	two	NUM
admet-2088	632	35	weeks	week	NOUN
admet-2088	632	36	of	of	ADP
admet-2088	632	37	study	study	NOUN
admet-2088	632	38	.	.	PUNCT
admet-2088	633	1	reported	report	VERB
admet-2088	633	2	research	research	NOUN
admet-2088	633	3	on	on	ADP
admet-2088	633	4	types	type	NOUN
admet-2088	633	5	of	of	ADP
admet-2088	633	6	nms	nms	NOUN
admet-2088	633	7	,	,	PUNCT
admet-2088	633	8	types	type	NOUN
admet-2088	633	9	of	of	ADP
admet-2088	633	10	dds	dds	PROPN
admet-2088	633	11	along	along	ADP
admet-2088	633	12	with	with	ADP
admet-2088	633	13	the	the	DET
admet-2088	633	14	therapeutic	therapeutic	ADJ
admet-2088	633	15	molecules	molecule	NOUN
admet-2088	633	16	,	,	PUNCT
admet-2088	633	17	polymers	polymer	NOUN
admet-2088	633	18	and	and	CCONJ
admet-2088	633	19	the	the	DET
admet-2088	633	20	obtained	obtain	VERB
admet-2088	633	21	results	result	NOUN
admet-2088	633	22	are	be	AUX
admet-2088	633	23	summarized	summarize	VERB
admet-2088	633	24	in	in	ADP
admet-2088	633	25	table	table	NOUN
admet-2088	633	26	1	1	NUM
admet-2088	633	27	.	.	PUNCT
admet-2088	633	28	table	table	NOUN
admet-2088	633	29	1	1	NUM
admet-2088	633	30	.	.	PUNCT
admet-2088	634	1	the	the	DET
admet-2088	634	2	summary	summary	NOUN
admet-2088	634	3	of	of	ADP
admet-2088	634	4	the	the	DET
admet-2088	634	5	reported	report	VERB
admet-2088	634	6	research	research	NOUN
admet-2088	634	7	involving	involve	VERB
admet-2088	634	8	types	type	NOUN
admet-2088	634	9	of	of	ADP
admet-2088	634	10	nms	nms	PROPN
admet-2088	634	11	and	and	CCONJ
admet-2088	634	12	dds	dds	PROPN
admet-2088	634	13	,	,	PUNCT
admet-2088	634	14	along	along	ADP
admet-2088	634	15	with	with	ADP
admet-2088	634	16	therapeutic	therapeutic	ADJ
admet-2088	634	17	molecules	molecule	NOUN
admet-2088	634	18	,	,	PUNCT
admet-2088	634	19	polymers	polymer	NOUN
admet-2088	634	20	and	and	CCONJ
admet-2088	634	21	the	the	DET
admet-2088	634	22	obtained	obtain	VERB
admet-2088	634	23	result	result	NOUN
admet-2088	634	24	types	type	NOUN
admet-2088	634	25	of	of	ADP
admet-2088	634	26	nm	nm	ADJ
admet-2088	634	27	types	type	NOUN
admet-2088	634	28	of	of	ADP
admet-2088	634	29	dds	dds	PROPN
admet-2088	634	30	therapeutic	therapeutic	ADJ
admet-2088	634	31	agent	agent	NOUN
admet-2088	634	32	polymer	polymer	NOUN
admet-2088	634	33	result	result	NOUN
admet-2088	634	34	ref	ref	NOUN
admet-2088	634	35	.	.	PUNCT
admet-2088	635	1	gold	gold	PROPN
admet-2088	635	2	nps	nps	PROPN
admet-2088	635	3	nanocomposite	nanocomposite	PROPN
admet-2088	635	4	(	(	PUNCT
admet-2088	635	5	gold	gold	NOUN
admet-2088	635	6	nanoclusters	nanocluster	NOUN
admet-2088	635	7	)	)	PUNCT
admet-2088	635	8	azd8055	azd8055	VERB
admet-2088	635	9	albumin	albumin	ADJ
admet-2088	635	10	significant	significant	ADJ
admet-2088	635	11	cellular	cellular	ADJ
admet-2088	635	12	toxicity	toxicity	NOUN
admet-2088	635	13	with	with	ADP
admet-2088	635	14	decreasing	decrease	VERB
admet-2088	635	15	the	the	DET
admet-2088	635	16	tumor	tumor	NOUN
admet-2088	635	17	surface	surface	NOUN
admet-2088	635	18	[	[	X
admet-2088	635	19	80	80	NUM
admet-2088	635	20	]	]	X
admet-2088	635	21	nanocomposite	nanocomposite	PROPN
admet-2088	635	22	chalcones	chalcone	VERB
admet-2088	635	23	antitumor	antitumor	PROPN
admet-2088	635	24	activity	activity	NOUN
admet-2088	635	25	through	through	ADP
admet-2088	635	26	the	the	DET
admet-2088	635	27	generation	generation	NOUN
admet-2088	635	28	of	of	ADP
admet-2088	635	29	ros	ros	PROPN
admet-2088	635	30	[	[	X
admet-2088	635	31	81	81	NUM
admet-2088	635	32	]	]	PUNCT
admet-2088	635	33	nps	nps	PROPN
admet-2088	635	34	paclitaxel	paclitaxel	PROPN
admet-2088	635	35	antimelanoma	antimelanoma	NOUN
admet-2088	635	36	activity	activity	NOUN
admet-2088	635	37	through	through	ADP
admet-2088	635	38	the	the	DET
admet-2088	635	39	generation	generation	NOUN
admet-2088	635	40	of	of	ADP
admet-2088	635	41	ros	ros	PROPN
admet-2088	635	42	and	and	CCONJ
admet-2088	635	43	induction	induction	NOUN
admet-2088	635	44	of	of	ADP
admet-2088	635	45	apoptosis	apoptosis	NOUN
admet-2088	635	46	[	[	X
admet-2088	635	47	83	83	NUM
admet-2088	635	48	]	]	X
admet-2088	635	49	nanocomposite	nanocomposite	NOUN
admet-2088	635	50	(	(	PUNCT
admet-2088	635	51	gold	gold	NOUN
admet-2088	635	52	nanorods	nanorod	NOUN
admet-2088	635	53	)	)	PUNCT
admet-2088	635	54	gum	gum	NOUN
admet-2088	635	55	arabic	arabic	NOUN
admet-2088	635	56	reduced	reduce	VERB
admet-2088	635	57	primary	primary	ADJ
admet-2088	635	58	tumour	tumour	NOUN
admet-2088	635	59	growth	growth	NOUN
admet-2088	635	60	by	by	ADP
admet-2088	635	61	45	45	NUM
admet-2088	635	62	%	%	NOUN
admet-2088	635	63	and	and	CCONJ
admet-2088	635	64	reduced	reduce	VERB
admet-2088	635	65	melanoma	melanoma	NOUN
admet-2088	635	66	metastasis	metastasis	NOUN
admet-2088	635	67	[	[	X
admet-2088	635	68	9	9	NUM
admet-2088	635	69	]	]	X
admet-2088	635	70	gold	gold	NOUN
admet-2088	635	71	-	-	PUNCT
admet-2088	635	72	nanoshell	nanoshell	NOUN
admet-2088	635	73	doxorubicin	doxorubicin	NOUN
admet-2088	635	74	antibody	antibody	NOUN
admet-2088	635	75	and	and	CCONJ
admet-2088	635	76	peg	peg	NOUN
admet-2088	635	77	expression	expression	NOUN
admet-2088	635	78	of	of	ADP
admet-2088	635	79	significantly	significantly	ADV
admet-2088	635	80	higher	high	ADJ
admet-2088	635	81	level	level	NOUN
admet-2088	635	82	of	of	ADP
admet-2088	635	83	pd	pd	PROPN
admet-2088	635	84	-	-	PROPN
admet-2088	635	85	l1	l1	PROPN
admet-2088	635	86	.	.	PUNCT
admet-2088	636	1	precise	precise	ADJ
admet-2088	636	2	targeting	targeting	NOUN
admet-2088	636	3	and	and	CCONJ
admet-2088	636	4	delivery	delivery	NOUN
admet-2088	636	5	of	of	ADP
admet-2088	636	6	drugs	drug	NOUN
admet-2088	636	7	to	to	ADP
admet-2088	636	8	melanoma	melanoma	NOUN
admet-2088	636	9	cells	cell	NOUN
admet-2088	636	10	[	[	X
admet-2088	636	11	84	84	NUM
admet-2088	636	12	]	]	PUNCT
admet-2088	636	13	theranostic	theranostic	ADJ
admet-2088	636	14	nanoprobe	nanoprobe	NOUN
admet-2088	636	15	p	p	NOUN
admet-2088	636	16	-	-	PUNCT
admet-2088	636	17	mba	mba	NOUN
admet-2088	636	18	anti	anti	ADJ
admet-2088	636	19	-	-	ADJ
admet-2088	636	20	muc18	muc18	ADJ
admet-2088	636	21	single	single	ADJ
admet-2088	636	22	chain	chain	NOUN
admet-2088	636	23	antibody	antibody	NOUN
admet-2088	636	24	(	(	PUNCT
admet-2088	636	25	scfy	scfy	NOUN
admet-2088	636	26	)	)	PUNCT
admet-2088	636	27	in	in	ADP
admet-2088	636	28	vivo	vivo	ADJ
admet-2088	636	29	melanoma	melanoma	NOUN
admet-2088	636	30	site	site	NOUN
admet-2088	636	31	tracing	tracing	NOUN
admet-2088	636	32	,	,	PUNCT
admet-2088	636	33	biodistribution	biodistribution	NOUN
admet-2088	636	34	study	study	NOUN
admet-2088	636	35	and	and	CCONJ
admet-2088	636	36	targeted	target	VERB
admet-2088	636	37	treatment	treatment	NOUN
admet-2088	636	38	[	[	X
admet-2088	636	39	86	86	NUM
admet-2088	636	40	]	]	X
admet-2088	636	41	nanocomposite	nanocomposite	NOUN
admet-2088	636	42	ha	ha	INTJ
admet-2088	636	43	and	and	CCONJ
admet-2088	636	44	oleic	oleic	ADV
admet-2088	636	45	acid	acid	PROPN
admet-2088	636	46	more	more	ADV
admet-2088	636	47	effective	effective	ADJ
admet-2088	636	48	against	against	ADP
admet-2088	636	49	nonmetastatic	nonmetastatic	ADJ
admet-2088	636	50	melanoma	melanoma	NOUN
admet-2088	636	51	or	or	CCONJ
admet-2088	636	52	other	other	ADJ
admet-2088	636	53	superficial	superficial	ADJ
admet-2088	636	54	tumours	tumour	NOUN
admet-2088	636	55	[	[	X
admet-2088	636	56	87	87	NUM
admet-2088	636	57	]	]	PUNCT
admet-2088	636	58	nanocomposite	nanocomposite	PROPN
admet-2088	636	59	folic	folic	PROPN
admet-2088	636	60	acid	acid	NOUN
admet-2088	636	61	decreased	decrease	VERB
admet-2088	636	62	viability	viability	NOUN
admet-2088	636	63	of	of	ADP
admet-2088	636	64	melanoma	melanoma	NOUN
admet-2088	636	65	cells	cell	NOUN
admet-2088	636	66	and	and	CCONJ
admet-2088	636	67	decrease	decrease	NOUN
admet-2088	636	68	in	in	ADP
admet-2088	636	69	side	side	NOUN
admet-2088	636	70	effects	effect	NOUN
admet-2088	636	71	.	.	PUNCT
admet-2088	637	1	[	[	X
admet-2088	637	2	88	88	NUM
admet-2088	637	3	]	]	X
admet-2088	637	4	gold	gold	PROPN
admet-2088	637	5	nps	nps	PROPN
admet-2088	637	6	and	and	CCONJ
admet-2088	637	7	tio2	tio2	PROPN
admet-2088	637	8	nanorods	nanorod	NOUN
admet-2088	637	9	nanocomposite	nanocomposite	NOUN
admet-2088	637	10	reduction	reduction	NOUN
admet-2088	637	11	of	of	ADP
admet-2088	637	12	cell	cell	NOUN
admet-2088	637	13	viability	viability	NOUN
admet-2088	637	14	to	to	ADP
admet-2088	637	15	less	less	ADJ
admet-2088	637	16	than	than	ADP
admet-2088	637	17	1	1	NUM
admet-2088	637	18	%	%	NOUN
admet-2088	637	19	[	[	X
admet-2088	637	20	89	89	NUM
admet-2088	637	21	]	]	SYM
admet-2088	637	22	au	au	PROPN
admet-2088	637	23	-	-	PUNCT
admet-2088	637	24	mno2	mno2	PROPN
admet-2088	637	25	nanocomposite	nanocomposite	PROPN
admet-2088	637	26	nanocomposite	nanocomposite	PROPN
admet-2088	637	27	cytotoxicity	cytotoxicity	NOUN
admet-2088	637	28	of	of	ADP
admet-2088	637	29	c540	c540	PROPN
admet-2088	637	30	cell	cell	NOUN
admet-2088	637	31	lines	line	NOUN
admet-2088	637	32	in	in	ADP
admet-2088	637	33	a	a	DET
admet-2088	637	34	dose	dose	NOUN
admet-2088	637	35	-	-	PUNCT
admet-2088	637	36	dependent	dependent	ADJ
admet-2088	637	37	manner	manner	NOUN
admet-2088	638	1	[	[	X
admet-2088	638	2	90	90	NUM
admet-2088	638	3	]	]	X
admet-2088	638	4	silver	silver	PROPN
admet-2088	638	5	nps	nps	PROPN
admet-2088	638	6	nanocomposite	nanocomposite	PROPN
admet-2088	638	7	hydrogel	hydrogel	NOUN
admet-2088	638	8	chitosan	chitosan	NOUN
admet-2088	638	9	and	and	CCONJ
admet-2088	638	10	starch	starch	VERB
admet-2088	638	11	a	a	DET
admet-2088	638	12	dose	dose	NOUN
admet-2088	638	13	-	-	PUNCT
admet-2088	638	14	dependent	dependent	ADJ
admet-2088	638	15	decrease	decrease	NOUN
admet-2088	638	16	in	in	ADP
admet-2088	638	17	%	%	NOUN
admet-2088	638	18	of	of	ADP
admet-2088	638	19	cell	cell	NOUN
admet-2088	638	20	viability	viability	NOUN
admet-2088	638	21	[	[	X
admet-2088	638	22	98	98	NUM
admet-2088	638	23	]	]	X
admet-2088	638	24	organometallic	organometallic	ADJ
admet-2088	638	25	nanocomposite	nanocomposite	NOUN
admet-2088	638	26	pheophorbide	pheophorbide	NOUN
admet-2088	638	27	-	-	PUNCT
admet-2088	638	28	a(ph	a(ph	NOUN
admet-2088	638	29	-	-	PUNCT
admet-2088	638	30	a	a	NOUN
admet-2088	638	31	)	)	PUNCT
admet-2088	638	32	effective	effective	ADJ
admet-2088	638	33	suppression	suppression	NOUN
admet-2088	638	34	of	of	ADP
admet-2088	638	35	tumour	tumour	NOUN
admet-2088	638	36	growth	growth	NOUN
admet-2088	638	37	in	in	ADP
admet-2088	638	38	vivo	vivo	NOUN
admet-2088	638	39	[	[	X
admet-2088	638	40	99	99	NUM
admet-2088	638	41	]	]	PUNCT
admet-2088	638	42	nanohybrid	nanohybrid	NOUN
admet-2088	638	43	biohydrogel	biohydrogel	PROPN
admet-2088	638	44	cmc	cmc	PROPN
admet-2088	638	45	and	and	CCONJ
admet-2088	638	46	poly(acrylic	poly(acrylic	PROPN
admet-2088	638	47	acid	acid	NOUN
admet-2088	638	48	-	-	PUNCT
admet-2088	638	49	co	co	NOUN
admet-2088	638	50	-	-	ADJ
admet-2088	638	51	maleic	maleic	ADJ
admet-2088	638	52	acid	acid	NOUN
admet-2088	638	53	reduced	reduce	VERB
admet-2088	638	54	the	the	DET
admet-2088	638	55	viability	viability	NOUN
admet-2088	638	56	of	of	ADP
admet-2088	638	57	melanoma	melanoma	NOUN
admet-2088	638	58	cells	cell	NOUN
admet-2088	638	59	in	in	ADP
admet-2088	638	60	a	a	DET
admet-2088	638	61	dose	dose	NOUN
admet-2088	638	62	and	and	CCONJ
admet-2088	638	63	time	time	NOUN
admet-2088	638	64	-	-	PUNCT
admet-2088	638	65	dependent	dependent	ADJ
admet-2088	638	66	manner	manner	NOUN
admet-2088	638	67	by	by	ADP
admet-2088	638	68	the	the	DET
admet-2088	638	69	generation	generation	NOUN
admet-2088	638	70	of	of	ADP
admet-2088	638	71	ros	ros	PROPN
admet-2088	638	72	and	and	CCONJ
admet-2088	638	73	cell	cell	NOUN
admet-2088	638	74	death	death	NOUN
admet-2088	638	75	[	[	X
admet-2088	638	76	100	100	NUM
admet-2088	638	77	]	]	PUNCT
admet-2088	638	78	nanohybrid	nanohybrid	NOUN
admet-2088	638	79	hydrogel	hydrogel	NOUN
admet-2088	638	80	doxorubicin	doxorubicin	PROPN
admet-2088	638	81	cmc	cmc	PROPN
admet-2088	638	82	killing	killing	NOUN
admet-2088	638	83	of	of	ADP
admet-2088	638	84	melanoma	melanoma	NOUN
admet-2088	638	85	cells	cell	NOUN
admet-2088	638	86	synergistically	synergistically	ADV
admet-2088	638	87	and	and	CCONJ
admet-2088	638	88	antibacterial	antibacterial	ADJ
admet-2088	638	89	effect	effect	NOUN
admet-2088	638	90	[	[	X
admet-2088	638	91	101	101	NUM
admet-2088	638	92	]	]	PUNCT
admet-2088	638	93	nanocomposite	nanocomposite	NOUN
admet-2088	638	94	cisplatin	cisplatin	PROPN
admet-2088	638	95	pvp	pvp	NOUN
admet-2088	638	96	induction	induction	NOUN
admet-2088	638	97	of	of	ADP
admet-2088	638	98	both	both	CCONJ
admet-2088	638	99	apoptosis	apoptosis	NOUN
admet-2088	638	100	and	and	CCONJ
admet-2088	638	101	necrosis	necrosis	NOUN
admet-2088	638	102	[	[	X
admet-2088	638	103	102	102	NUM
admet-2088	638	104	]	]	X
admet-2088	638	105	silver	silver	PROPN
admet-2088	638	106	nps	nps	PROPN
admet-2088	638	107	and	and	CCONJ
admet-2088	638	108	platinum	platinum	PROPN
admet-2088	638	109	nps	nps	PROPN
admet-2088	638	110	nanocomposite	nanocomposite	PROPN
admet-2088	638	111	selective	selective	ADJ
admet-2088	638	112	cytotoxicity	cytotoxicity	NOUN
admet-2088	638	113	of	of	ADP
admet-2088	638	114	melanoma	melanoma	NOUN
admet-2088	638	115	cells	cell	NOUN
admet-2088	638	116	through	through	ADP
admet-2088	638	117	enhanced	enhanced	ADJ
admet-2088	638	118	permeability	permeability	NOUN
admet-2088	638	119	and	and	CCONJ
admet-2088	638	120	retention	retention	NOUN
admet-2088	638	121	in	in	ADP
admet-2088	638	122	these	these	DET
admet-2088	638	123	cells	cell	NOUN
admet-2088	638	124	[	[	X
admet-2088	639	1	2	2	X
admet-2088	639	2	]	]	SYM
admet-2088	639	3	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	639	4	m.	m.	NOUN
admet-2088	639	5	kulkarni	kulkarni	PROPN
admet-2088	639	6	et	et	PROPN
admet-2088	639	7	al	al	PROPN
admet-2088	639	8	.	.	PROPN
admet-2088	639	9	admet	admet	PROPN
admet-2088	639	10	&	&	CCONJ
admet-2088	639	11	dmpk	dmpk	PROPN
admet-2088	639	12	12(1	12(1	PROPN
admet-2088	639	13	)	)	PUNCT
admet-2088	639	14	(	(	PUNCT
admet-2088	639	15	2024	2024	NUM
admet-2088	639	16	)	)	PUNCT
admet-2088	639	17	107	107	NUM
admet-2088	639	18	-	-	SYM
admet-2088	639	19	150	150	NUM
admet-2088	639	20	132	132	NUM
admet-2088	639	21	types	type	NOUN
admet-2088	639	22	of	of	ADP
admet-2088	639	23	nm	nm	ADJ
admet-2088	639	24	types	type	NOUN
admet-2088	639	25	of	of	ADP
admet-2088	639	26	dds	dds	PROPN
admet-2088	639	27	therapeutic	therapeutic	ADJ
admet-2088	639	28	agent	agent	NOUN
admet-2088	639	29	polymer	polymer	NOUN
admet-2088	639	30	result	result	NOUN
admet-2088	639	31	ref	ref	NOUN
admet-2088	639	32	.	.	PUNCT
admet-2088	640	1	ctnps	ctnps	PROPN
admet-2088	640	2	ferroptosisactivating	ferroptosisactivate	VERB
admet-2088	640	3	vaccine	vaccine	NOUN
admet-2088	640	4	ova	ova	VERB
admet-2088	640	5	and	and	CCONJ
admet-2088	640	6	melanoma	melanoma	VERB
admet-2088	640	7	b16	b16	NOUN
admet-2088	640	8	-	-	PUNCT
admet-2088	640	9	ova	ova	ADJ
admet-2088	640	10	membrane	membrane	NOUN
admet-2088	640	11	trigger	trigger	NOUN
admet-2088	640	12	ferroptosis	ferroptosis	NOUN
admet-2088	640	13	and	and	CCONJ
admet-2088	640	14	induction	induction	NOUN
admet-2088	640	15	of	of	ADP
admet-2088	640	16	immunogenic	immunogenic	ADJ
admet-2088	640	17	cell	cell	NOUN
admet-2088	640	18	death	death	NOUN
admet-2088	640	19	through	through	ADP
admet-2088	640	20	strong	strong	ADJ
admet-2088	640	21	immune	immune	ADJ
admet-2088	640	22	response	response	NOUN
admet-2088	640	23	in	in	ADP
admet-2088	640	24	vivo	vivo	NOUN
admet-2088	640	25	[	[	X
admet-2088	640	26	110	110	NUM
admet-2088	640	27	]	]	X
admet-2088	640	28	cuo2nps	cuo2nps	PROPN
admet-2088	640	29	nanocomposite	nanocomposite	PROPN
admet-2088	640	30	pvp	pvp	PROPN
admet-2088	640	31	transform	transform	VERB
admet-2088	640	32	endogenous	endogenous	ADJ
admet-2088	640	33	h2o2	h2o2	NOUN
admet-2088	640	34	into	into	ADP
admet-2088	640	35	highly	highly	ADV
admet-2088	640	36	toxic	toxic	ADJ
admet-2088	641	1	oh	oh	INTJ
admet-2088	641	2	and	and	CCONJ
admet-2088	641	3	glutathione	glutathione	NOUN
admet-2088	641	4	(	(	PUNCT
admet-2088	641	5	gsh)-scavenging	gsh)-scavenge	VERB
admet-2088	641	6	for	for	ADP
admet-2088	641	7	ros	ros	PROPN
admet-2088	641	8	-	-	PUNCT
admet-2088	641	9	induced	induce	VERB
admet-2088	641	10	tumour	tumour	NOUN
admet-2088	641	11	cell	cell	NOUN
admet-2088	641	12	death	death	NOUN
admet-2088	641	13	[	[	X
admet-2088	641	14	21	21	NUM
admet-2088	641	15	]	]	X
admet-2088	641	16	pt	pt	PROPN
admet-2088	641	17	-	-	PUNCT
admet-2088	641	18	nps	nps	PROPN
admet-2088	641	19	nanocomposite	nanocomposite	NOUN
admet-2088	641	20	doxorubicin	doxorubicin	PROPN
admet-2088	641	21	peg	peg	NOUN
admet-2088	641	22	inhibition	inhibition	NOUN
admet-2088	641	23	of	of	ADP
admet-2088	641	24	cancer	cancer	NOUN
admet-2088	641	25	cell	cell	NOUN
admet-2088	641	26	proliferation	proliferation	NOUN
admet-2088	641	27	and	and	CCONJ
admet-2088	641	28	induced	induce	VERB
admet-2088	641	29	apoptosis	apoptosis	NOUN
admet-2088	641	30	of	of	ADP
admet-2088	641	31	cancer	cancer	NOUN
admet-2088	641	32	cells	cell	NOUN
admet-2088	641	33	[	[	X
admet-2088	641	34	113	113	NUM
admet-2088	641	35	]	]	SYM
admet-2088	641	36	pt	pt	PROPN
admet-2088	641	37	mesoporous	mesoporous	PROPN
admet-2088	641	38	nps	nps	PROPN
admet-2088	641	39	(	(	PUNCT
admet-2088	641	40	pt	pt	PROPN
admet-2088	641	41	-	-	ADJ
admet-2088	641	42	mnps	mnps	ADJ
admet-2088	641	43	)	)	PUNCT
admet-2088	641	44	nps	nps	PROPN
admet-2088	641	45	--	--	PUNCT
admet-2088	641	46	low	low	ADJ
admet-2088	641	47	melanoma	melanoma	NOUN
admet-2088	641	48	cell	cell	NOUN
admet-2088	641	49	viability	viability	NOUN
admet-2088	641	50	(	(	PUNCT
admet-2088	641	51	1	1	PROPN
admet-2088	641	52	%	%	NOUN
admet-2088	641	53	)	)	PUNCT
admet-2088	641	54	due	due	ADP
admet-2088	641	55	to	to	ADP
admet-2088	641	56	significant	significant	ADJ
admet-2088	641	57	generation	generation	NOUN
admet-2088	641	58	of	of	ADP
admet-2088	641	59	ros	ros	PROPN
admet-2088	641	60	[	[	X
admet-2088	641	61	119	119	NUM
admet-2088	641	62	]	]	PUNCT
admet-2088	641	63	silica	silica	NOUN
admet-2088	641	64	nps	nps	PROPN
admet-2088	641	65	nanocomplex	nanocomplex	PROPN
admet-2088	641	66	curcumin	curcumin	NOUN
admet-2088	641	67	higher	high	ADJ
admet-2088	641	68	cancerous	cancerous	ADJ
admet-2088	641	69	cell	cell	NOUN
admet-2088	641	70	death	death	NOUN
admet-2088	641	71	due	due	ADP
admet-2088	641	72	to	to	ADP
admet-2088	641	73	the	the	DET
admet-2088	641	74	formation	formation	NOUN
admet-2088	641	75	ros	ros	PROPN
admet-2088	642	1	[	[	X
admet-2088	642	2	125	125	NUM
admet-2088	642	3	]	]	X
admet-2088	642	4	mesoporous	mesoporous	ADJ
admet-2088	642	5	silica	silica	PROPN
admet-2088	642	6	nps	nps	PROPN
admet-2088	642	7	nanocomplex	nanocomplex	PROPN
admet-2088	642	8	verteporfin	verteporfin	PROPN
admet-2088	642	9	selectively	selectively	ADV
admet-2088	642	10	reduced	reduce	VERB
admet-2088	642	11	cancer	cancer	NOUN
admet-2088	642	12	cell	cell	NOUN
admet-2088	642	13	proliferation	proliferation	NOUN
admet-2088	642	14	[	[	X
admet-2088	642	15	28	28	NUM
admet-2088	642	16	]	]	X
admet-2088	642	17	mesoporoussilica	mesoporoussilica	PROPN
admet-2088	642	18	nps	nps	PROPN
admet-2088	642	19	nps	nps	PROPN
admet-2088	642	20	selective	selective	ADJ
admet-2088	642	21	tumour	tumour	NOUN
admet-2088	642	22	growth	growth	NOUN
admet-2088	642	23	inhibition	inhibition	NOUN
admet-2088	642	24	due	due	ADJ
admet-2088	642	25	to	to	ADP
admet-2088	642	26	higher	high	ADJ
admet-2088	642	27	amount	amount	NOUN
admet-2088	642	28	ros	ros	PROPN
admet-2088	642	29	formation	formation	NOUN
admet-2088	643	1	[	[	X
admet-2088	643	2	126	126	NUM
admet-2088	643	3	]	]	X
admet-2088	643	4	pegylated	pegylate	VERB
admet-2088	643	5	silica	silica	PROPN
admet-2088	643	6	nps	nps	PROPN
admet-2088	643	7	core	core	NOUN
admet-2088	643	8	-	-	PUNCT
admet-2088	643	9	shell	shell	NOUN
admet-2088	643	10	nps	nps	PROPN
admet-2088	643	11	peg	peg	NOUN
admet-2088	643	12	and	and	CCONJ
admet-2088	643	13	αvβ3	αvβ3	NOUN
admet-2088	643	14	-	-	PUNCT
admet-2088	643	15	integrin	integrin	NOUN
admet-2088	643	16	melanoma	melanoma	NOUN
admet-2088	643	17	targeting	target	VERB
admet-2088	643	18	peptides	peptide	NOUN
admet-2088	643	19	precise	precise	ADJ
admet-2088	643	20	targeting	target	VERB
admet-2088	643	21	and	and	CCONJ
admet-2088	643	22	induced	induced	ADJ
admet-2088	643	23	ferroptosis	ferroptosis	NOUN
admet-2088	643	24	in	in	ADP
admet-2088	643	25	starved	starve	VERB
admet-2088	643	26	cancer	cancer	NOUN
admet-2088	643	27	cells	cell	NOUN
admet-2088	643	28	[	[	X
admet-2088	643	29	127	127	NUM
admet-2088	643	30	]	]	X
admet-2088	643	31	mesoporous	mesoporous	ADJ
admet-2088	643	32	silica	silica	PROPN
admet-2088	643	33	nps	nps	PROPN
admet-2088	643	34	2d	2d	PROPN
admet-2088	643	35	core	core	ADJ
admet-2088	643	36	-	-	PUNCT
admet-2088	643	37	shell	shell	NOUN
admet-2088	643	38	nanosystem	nanosystem	NOUN
admet-2088	643	39	with	with	ADP
admet-2088	643	40	silica	silica	NOUN
admet-2088	643	41	layer	layer	NOUN
admet-2088	643	42	cisplatin	cisplatin	NOUN
admet-2088	643	43	synergistic	synergistic	ADJ
admet-2088	643	44	pyroptosis	pyroptosis	NOUN
admet-2088	643	45	and	and	CCONJ
admet-2088	643	46	hyperthermia	hyperthermia	NOUN
admet-2088	643	47	of	of	ADP
admet-2088	643	48	melanoma	melanoma	ADJ
admet-2088	643	49	carcinoma	carcinoma	NOUN
admet-2088	643	50	[	[	X
admet-2088	643	51	129	129	NUM
admet-2088	643	52	]	]	X
admet-2088	643	53	mcm	mcm	PROPN
admet-2088	643	54	nps	nps	PROPN
admet-2088	643	55	quercetin	quercetin	NOUN
admet-2088	643	56	improves	improve	VERB
admet-2088	643	57	stability	stability	NOUN
admet-2088	643	58	of	of	ADP
admet-2088	643	59	quercetin	quercetin	NOUN
admet-2088	643	60	and	and	CCONJ
admet-2088	643	61	enhanced	enhanced	ADJ
admet-2088	643	62	quercetin	quercetin	NOUN
admet-2088	643	63	penetration	penetration	NOUN
admet-2088	643	64	across	across	ADP
admet-2088	643	65	skin	skin	NOUN
admet-2088	643	66	[	[	X
admet-2088	643	67	130	130	NUM
admet-2088	643	68	]	]	PUNCT
admet-2088	643	69	gold	gold	PROPN
admet-2088	643	70	nps	nps	PROPN
admet-2088	643	71	and	and	CCONJ
admet-2088	643	72	mesoporous	mesoporous	ADJ
admet-2088	643	73	silica	silica	PROPN
admet-2088	643	74	nps	nps	PROPN
admet-2088	643	75	gold	gold	NOUN
admet-2088	643	76	nanoshell	nanoshell	NOUN
admet-2088	643	77	on	on	ADP
admet-2088	643	78	rod	rod	NOUN
admet-2088	643	79	-	-	PUNCT
admet-2088	643	80	like	like	ADJ
admet-2088	643	81	mesoporous	mesoporous	ADJ
admet-2088	643	82	silica	silica	NOUN
admet-2088	643	83	nps	nps	PROPN
admet-2088	643	84	effective	effective	ADJ
admet-2088	643	85	penetration	penetration	NOUN
admet-2088	643	86	into	into	ADP
admet-2088	643	87	melanoma	melanoma	NOUN
admet-2088	643	88	tissues	tissue	NOUN
admet-2088	643	89	and	and	CCONJ
admet-2088	643	90	potential	potential	ADJ
admet-2088	643	91	ablation	ablation	NOUN
admet-2088	643	92	of	of	ADP
admet-2088	643	93	malignant	malignant	ADJ
admet-2088	643	94	melanoma	melanoma	NOUN
admet-2088	643	95	cells	cell	NOUN
admet-2088	643	96	[	[	X
admet-2088	643	97	128	128	NUM
admet-2088	643	98	]	]	X
admet-2088	643	99	tio2	tio2	PROPN
admet-2088	643	100	nps	nps	PROPN
admet-2088	643	101	nanocomposite	nanocomposite	PROPN
admet-2088	643	102	curcumin	curcumin	PROPN
admet-2088	643	103	dna	dna	PROPN
admet-2088	643	104	damage	damage	NOUN
admet-2088	643	105	,	,	PUNCT
admet-2088	643	106	apoptosis	apoptosis	NOUN
admet-2088	643	107	and	and	CCONJ
admet-2088	643	108	stopping	stop	VERB
admet-2088	643	109	the	the	DET
admet-2088	643	110	cells	cell	NOUN
admet-2088	643	111	at	at	ADP
admet-2088	643	112	the	the	DET
admet-2088	643	113	g2	g2	PROPN
admet-2088	643	114	/	/	SYM
admet-2088	643	115	m	m	PROPN
admet-2088	643	116	phase	phase	NOUN
admet-2088	643	117	[	[	X
admet-2088	643	118	135	135	NUM
admet-2088	643	119	]	]	PUNCT
admet-2088	643	120	iron	iron	NOUN
admet-2088	643	121	nps	nps	PROPN
admet-2088	643	122	mpn	mpn	PROPN
admet-2088	643	123	nanocomposite	nanocomposite	PROPN
admet-2088	643	124	cabazitaxel	cabazitaxel	PROPN
admet-2088	643	125	chitosan	chitosan	PROPN
admet-2088	643	126	higher	high	ADJ
admet-2088	643	127	retention	retention	NOUN
admet-2088	643	128	time	time	NOUN
admet-2088	643	129	in	in	ADP
admet-2088	643	130	tumor	tumor	NOUN
admet-2088	643	131	tissues	tissue	NOUN
admet-2088	643	132	and	and	CCONJ
admet-2088	643	133	thereby	thereby	ADV
admet-2088	643	134	significant	significant	ADJ
admet-2088	643	135	reduction	reduction	NOUN
admet-2088	643	136	of	of	ADP
admet-2088	643	137	tumor	tumor	NOUN
admet-2088	643	138	growth	growth	NOUN
admet-2088	643	139	[	[	X
admet-2088	643	140	144	144	NUM
admet-2088	643	141	]	]	X
admet-2088	643	142	mpn	mpn	PROPN
admet-2088	643	143	nanocomposite	nanocomposite	PROPN
admet-2088	643	144	gallic	gallic	PROPN
admet-2088	643	145	acid	acid	PROPN
admet-2088	643	146	hyaluronic	hyaluronic	NOUN
admet-2088	643	147	acid	acid	NOUN
admet-2088	643	148	synergistic	synergistic	ADJ
admet-2088	643	149	therapy	therapy	NOUN
admet-2088	643	150	(	(	PUNCT
admet-2088	643	151	pdt	pdt	PROPN
admet-2088	643	152	and	and	CCONJ
admet-2088	643	153	cdt	cdt	PROPN
admet-2088	643	154	)	)	PUNCT
admet-2088	643	155	against	against	ADP
admet-2088	643	156	melanoma	melanoma	NOUN
admet-2088	643	157	due	due	ADP
admet-2088	643	158	to	to	ADP
admet-2088	643	159	the	the	DET
admet-2088	643	160	generation	generation	NOUN
admet-2088	643	161	of	of	ADP
admet-2088	643	162	ros	ros	PROPN
admet-2088	643	163	[	[	X
admet-2088	643	164	145	145	NUM
admet-2088	643	165	]	]	PUNCT
admet-2088	643	166	nanocomposite	nanocomposite	ADJ
admet-2088	643	167	hydrogel	hydrogel	NOUN
admet-2088	643	168	polydopaminefe(iii)doxorubicin	polydopaminefe(iii)doxorubicin	VERB
admet-2088	643	169	np	np	AUX
admet-2088	643	170	alginate	alginate	VERB
admet-2088	643	171	significant	significant	ADJ
admet-2088	643	172	inhibition	inhibition	NOUN
admet-2088	643	173	of	of	ADP
admet-2088	643	174	proliferation	proliferation	NOUN
admet-2088	643	175	and	and	CCONJ
admet-2088	643	176	migration	migration	NOUN
admet-2088	643	177	of	of	ADP
admet-2088	643	178	melanoma	melanoma	NOUN
admet-2088	643	179	cells	cell	NOUN
admet-2088	643	180	due	due	ADJ
admet-2088	643	181	to	to	ADP
admet-2088	643	182	hyperthermia	hyperthermia	NOUN
admet-2088	643	183	.	.	PUNCT
admet-2088	644	1	it	it	PRON
admet-2088	644	2	also	also	ADV
admet-2088	644	3	induces	induce	VERB
admet-2088	644	4	skin	skin	NOUN
admet-2088	644	5	generation	generation	NOUN
admet-2088	644	6	.	.	PUNCT
admet-2088	645	1	[	[	X
admet-2088	645	2	146	146	NUM
admet-2088	645	3	]	]	PUNCT
admet-2088	645	4	swcnts	swcnt	NOUN
admet-2088	645	5	nanovector	nanovector	NOUN
admet-2088	645	6	doxorubicin	doxorubicin	PROPN
admet-2088	645	7	ceased	cease	VERB
admet-2088	645	8	the	the	DET
admet-2088	645	9	tumour	tumour	NOUN
admet-2088	645	10	growth	growth	NOUN
admet-2088	645	11	without	without	ADP
admet-2088	645	12	producing	produce	VERB
admet-2088	645	13	systemic	systemic	ADJ
admet-2088	645	14	side	side	NOUN
admet-2088	645	15	effects	effect	NOUN
admet-2088	645	16	[	[	X
admet-2088	645	17	154	154	NUM
admet-2088	645	18	]	]	PUNCT
admet-2088	645	19	mwcnts	mwcnt	NOUN
admet-2088	645	20	nanocomposite	nanocomposite	PROPN
admet-2088	645	21	polypyrrole	polypyrrole	PROPN
admet-2088	645	22	concentration	concentration	NOUN
admet-2088	645	23	-	-	PUNCT
admet-2088	645	24	dependent	dependent	ADJ
admet-2088	645	25	cytotoxicity	cytotoxicity	NOUN
admet-2088	645	26	with	with	ADP
admet-2088	645	27	a	a	DET
admet-2088	645	28	cell	cell	NOUN
admet-2088	645	29	viability	viability	NOUN
admet-2088	645	30	of	of	ADP
admet-2088	645	31	8.9	8.9	NUM
admet-2088	645	32	%	%	NOUN
admet-2088	645	33	due	due	ADP
admet-2088	645	34	to	to	ADP
admet-2088	645	35	hyperthermia	hyperthermia	NOUN
admet-2088	645	36	[	[	X
admet-2088	645	37	155	155	NUM
admet-2088	645	38	]	]	X
admet-2088	645	39	rgo	rgo	PROPN
admet-2088	645	40	nanocomposite	nanocomposite	PROPN
admet-2088	645	41	hydrogel	hydrogel	PROPN
admet-2088	645	42	5	5	NUM
admet-2088	645	43	-	-	PUNCT
admet-2088	645	44	fluorouracil	fluorouracil	NOUN
admet-2088	645	45	cmarx	cmarx	NOUN
admet-2088	645	46	significant	significant	ADJ
admet-2088	645	47	anticancer	anticancer	NOUN
admet-2088	645	48	activities	activity	NOUN
admet-2088	645	49	and	and	CCONJ
admet-2088	645	50	antibacterial	antibacterial	ADJ
admet-2088	645	51	activities	activity	NOUN
admet-2088	645	52	[	[	X
admet-2088	645	53	167	167	NUM
admet-2088	645	54	]	]	PUNCT
admet-2088	645	55	ngo	ngo	PROPN
admet-2088	645	56	nanocomposite	nanocomposite	NOUN
admet-2088	645	57	sheets	sheet	NOUN
admet-2088	645	58	dacarbazine	dacarbazine	NOUN
admet-2088	645	59	chitosan	chitosan	NOUN
admet-2088	645	60	oligosaccharide	oligosaccharide	NOUN
admet-2088	645	61	and	and	CCONJ
admet-2088	645	62	cd47	cd47	PROPN
admet-2088	645	63	antibody	antibody	VERB
admet-2088	645	64	simultaneous	simultaneous	ADJ
admet-2088	645	65	induction	induction	NOUN
admet-2088	645	66	of	of	ADP
admet-2088	645	67	apoptosis	apoptosis	NOUN
admet-2088	645	68	through	through	ADP
admet-2088	645	69	the	the	DET
admet-2088	645	70	mitochondria	mitochondria	NOUN
admet-2088	645	71	apoptosis	apoptosis	NOUN
admet-2088	645	72	pathway	pathway	NOUN
admet-2088	646	1	[	[	X
admet-2088	646	2	168	168	NUM
admet-2088	646	3	]	]	PUNCT
admet-2088	646	4	graphene	graphene	NOUN
admet-2088	646	5	nanotransporter	nanotransporter	NOUN
admet-2088	646	6	fluorescence	fluorescence	NOUN
admet-2088	646	7	protein	protein	NOUN
admet-2088	646	8	expression	expression	NOUN
admet-2088	646	9	plasmid	plasmid	VERB
admet-2088	646	10	dna	dna	PROPN
admet-2088	646	11	(	(	PUNCT
admet-2088	646	12	pdna	pdna	PROPN
admet-2088	646	13	)	)	PUNCT
admet-2088	646	14	magnetic	magnetic	PROPN
admet-2088	646	15	nps	nps	PROPN
admet-2088	646	16	and	and	CCONJ
admet-2088	646	17	pei	pei	PROPN
admet-2088	646	18	efficient	efficient	ADJ
admet-2088	646	19	delivery	delivery	NOUN
admet-2088	646	20	of	of	ADP
admet-2088	646	21	pdna	pdna	NOUN
admet-2088	646	22	into	into	ADP
admet-2088	646	23	the	the	DET
admet-2088	646	24	melanoma	melanoma	NOUN
admet-2088	646	25	cells	cell	NOUN
admet-2088	646	26	through	through	ADP
admet-2088	646	27	condensation	condensation	NOUN
admet-2088	646	28	[	[	X
admet-2088	646	29	169	169	NUM
admet-2088	646	30	]	]	X
admet-2088	646	31	admet	admet	PROPN
admet-2088	646	32	&	&	CCONJ
admet-2088	646	33	dmpk	dmpk	PROPN
admet-2088	646	34	12(1	12(1	PROPN
admet-2088	646	35	)	)	PUNCT
admet-2088	646	36	(	(	PUNCT
admet-2088	646	37	2024	2024	NUM
admet-2088	646	38	)	)	PUNCT
admet-2088	646	39	107	107	NUM
admet-2088	646	40	-	-	SYM
admet-2088	646	41	150	150	NUM
admet-2088	646	42	nanomaterial	nanomaterial	NOUN
admet-2088	646	43	-	-	PUNCT
admet-2088	646	44	based	base	VERB
admet-2088	646	45	drug	drug	NOUN
admet-2088	646	46	delivery	delivery	NOUN
admet-2088	646	47	systems	system	NOUN
admet-2088	646	48	for	for	ADP
admet-2088	646	49	melanoma	melanoma	NOUN
admet-2088	646	50	therapy	therapy	NOUN
admet-2088	646	51	doi	doi	NOUN
admet-2088	646	52	:	:	PUNCT
admet-2088	646	53	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	646	54	133	133	NUM
admet-2088	646	55	types	type	NOUN
admet-2088	646	56	of	of	ADP
admet-2088	646	57	nm	nm	ADJ
admet-2088	646	58	types	type	NOUN
admet-2088	646	59	of	of	ADP
admet-2088	646	60	dds	dds	PROPN
admet-2088	646	61	therapeutic	therapeutic	ADJ
admet-2088	646	62	agent	agent	NOUN
admet-2088	646	63	polymer	polymer	NOUN
admet-2088	646	64	result	result	NOUN
admet-2088	646	65	ref	ref	NOUN
admet-2088	646	66	.	.	PUNCT
admet-2088	647	1	nano	nano	NOUN
admet-2088	647	2	-	-	PUNCT
admet-2088	647	3	diamonds	diamond	NOUN
admet-2088	647	4	nps	nps	PROPN
admet-2088	647	5	potential	potential	ADJ
admet-2088	647	6	reduction	reduction	NOUN
admet-2088	647	7	of	of	ADP
admet-2088	647	8	the	the	DET
admet-2088	647	9	metastasis	metastasis	NOUN
admet-2088	647	10	through	through	ADP
admet-2088	647	11	inhibition	inhibition	NOUN
admet-2088	647	12	of	of	ADP
admet-2088	647	13	the	the	DET
admet-2088	647	14	migration	migration	NOUN
admet-2088	647	15	of	of	ADP
admet-2088	647	16	hela	hela	ADJ
admet-2088	647	17	cells	cell	NOUN
admet-2088	647	18	[	[	X
admet-2088	647	19	170	170	NUM
admet-2088	647	20	]	]	PUNCT
admet-2088	647	21	polymeric	polymeric	ADJ
admet-2088	647	22	nanocapsules	nanocapsule	NOUN
admet-2088	647	23	nps	nps	PROPN
admet-2088	647	24	curcumin	curcumin	PROPN
admet-2088	647	25	pba	pba	PROPN
admet-2088	647	26	and	and	CCONJ
admet-2088	647	27	aema	aema	PROPN
admet-2088	647	28	selectively	selectively	ADV
admet-2088	647	29	killed	kill	VERB
admet-2088	647	30	more	more	ADJ
admet-2088	647	31	than	than	ADP
admet-2088	647	32	90	90	NUM
admet-2088	647	33	%	%	NOUN
admet-2088	647	34	of	of	ADP
admet-2088	647	35	human	human	ADJ
admet-2088	647	36	malignant	malignant	ADJ
admet-2088	647	37	melanoma	melanoma	NOUN
admet-2088	647	38	cells	cell	NOUN
admet-2088	647	39	[	[	X
admet-2088	647	40	183	183	NUM
admet-2088	647	41	]	]	PUNCT
admet-2088	647	42	hybrid	hybrid	ADJ
admet-2088	647	43	nps	nps	PROPN
admet-2088	647	44	vitamin	vitamin	NOUN
admet-2088	647	45	d3	d3	PROPN
admet-2088	647	46	plga	plga	NOUN
admet-2088	647	47	and	and	CCONJ
admet-2088	647	48	hydrogenated	hydrogenate	VERB
admet-2088	647	49	soy	soy	NOUN
admet-2088	647	50	phosphatidylcholine	phosphatidylcholine	NOUN
admet-2088	647	51	,	,	PUNCT
admet-2088	647	52	cholesterol	cholesterol	NOUN
admet-2088	647	53	and	and	CCONJ
admet-2088	647	54	1,2disteroyl	1,2disteroyl	PROPN
admet-2088	647	55	-	-	PUNCT
admet-2088	647	56	sn	sn	NOUN
admet-2088	647	57	-	-	PUNCT
admet-2088	647	58	glycero-3phospha	glycero-3phospha	NOUN
admet-2088	647	59	ethanolamine	ethanolamine	NOUN
admet-2088	647	60	n[succinyl	n[succinyl	NOUN
admet-2088	647	61	(	(	PUNCT
admet-2088	647	62	peg)-2000	peg)-2000	NUM
admet-2088	647	63	target	target	NOUN
admet-2088	647	64	b16	b16	VERB
admet-2088	647	65	melanoma	melanoma	NOUN
admet-2088	647	66	cells	cell	NOUN
admet-2088	647	67	efficiently	efficiently	ADV
admet-2088	648	1	[	[	X
admet-2088	648	2	184	184	NUM
admet-2088	648	3	]	]	X
admet-2088	648	4	nps	nps	PROPN
admet-2088	648	5	celecoxib	celecoxib	VERB
admet-2088	648	6	and	and	CCONJ
admet-2088	648	7	afuresertib	afuresertib	ADJ
admet-2088	648	8	plga	plga	NOUN
admet-2088	648	9	,	,	PUNCT
admet-2088	648	10	peg	peg	NOUN
admet-2088	648	11	and	and	CCONJ
admet-2088	648	12	targeting	target	VERB
admet-2088	648	13	peptide	peptide	NOUN
admet-2088	648	14	il4rpep-1	il4rpep-1	DET
admet-2088	648	15	enhancement	enhancement	NOUN
admet-2088	648	16	of	of	ADP
admet-2088	648	17	apoptosis	apoptosis	NOUN
admet-2088	648	18	and	and	CCONJ
admet-2088	648	19	regulation	regulation	NOUN
admet-2088	648	20	of	of	ADP
admet-2088	648	21	m2	m2	PROPN
admet-2088	648	22	macrophages	macrophage	NOUN
admet-2088	648	23	in	in	ADP
admet-2088	648	24	tumor	tumor	NOUN
admet-2088	648	25	cells	cell	NOUN
admet-2088	648	26	to	to	ADP
admet-2088	648	27	reprogram	reprogram	NOUN
admet-2088	648	28	m1	m1	PROPN
admet-2088	648	29	macrophages	macrophage	NOUN
admet-2088	648	30	[	[	X
admet-2088	648	31	185	185	NUM
admet-2088	648	32	]	]	PUNCT
admet-2088	648	33	dendrimers	dendrimer	NOUN
admet-2088	648	34	nanoconjugates	nanoconjugate	VERB
admet-2088	648	35	temozolomide	temozolomide	VERB
admet-2088	648	36	pamam	pamam	NOUN
admet-2088	648	37	-	-	PUNCT
admet-2088	648	38	peg	peg	NOUN
admet-2088	648	39	-	-	PUNCT
admet-2088	648	40	ge11	ge11	PROPN
admet-2088	648	41	-	-	PUNCT
admet-2088	648	42	ha	ha	INTJ
admet-2088	648	43	targeting	target	VERB
admet-2088	648	44	towards	towards	ADP
admet-2088	648	45	a375	a375	PROPN
admet-2088	648	46	human	human	ADJ
admet-2088	648	47	melanoma	melanoma	NOUN
admet-2088	648	48	cell	cell	NOUN
admet-2088	649	1	[	[	X
admet-2088	649	2	189	189	NUM
admet-2088	649	3	]	]	PUNCT
admet-2088	649	4	core	core	ADJ
admet-2088	649	5	-	-	PUNCT
admet-2088	649	6	shell	shell	NOUN
admet-2088	649	7	nanomicelles	nanomicelle	NOUN
admet-2088	649	8	dabrafenib	dabrafenib	NOUN
admet-2088	649	9	and	and	CCONJ
admet-2088	649	10	vemurafenib	vemurafenib	PROPN
admet-2088	649	11	g2	g2	PROPN
admet-2088	649	12	pamam	pamam	NOUN
admet-2088	649	13	head	head	NOUN
admet-2088	649	14	and	and	CCONJ
admet-2088	649	15	c18	c18	NOUN
admet-2088	649	16	aliphatic	aliphatic	ADJ
admet-2088	649	17	chains	chain	NOUN
admet-2088	649	18	release	release	NOUN
admet-2088	649	19	of	of	ADP
admet-2088	649	20	drugs	drug	NOUN
admet-2088	649	21	enhanced	enhance	VERB
admet-2088	649	22	at	at	ADP
admet-2088	649	23	acidic	acidic	ADJ
admet-2088	649	24	ph	ph	ADJ
admet-2088	649	25	5.0	5.0	NUM
admet-2088	649	26	and	and	CCONJ
admet-2088	649	27	enhanced	enhance	VERB
admet-2088	649	28	antimelanoma	antimelanoma	ADJ
admet-2088	649	29	response	response	NOUN
admet-2088	649	30	[	[	X
admet-2088	649	31	7	7	NUM
admet-2088	649	32	]	]	X
admet-2088	649	33	polymeric	polymeric	ADJ
admet-2088	649	34	micelles	micelle	NOUN
admet-2088	649	35	nanomicelleles	nanomicellele	NOUN
admet-2088	649	36	doxorubicin	doxorubicin	PROPN
admet-2088	649	37	mpeg	mpeg	PROPN
admet-2088	649	38	-	-	PUNCT
admet-2088	649	39	b	b	NOUN
admet-2088	649	40	-	-	PUNCT
admet-2088	649	41	plaga	plaga	NOUN
admet-2088	649	42	and	and	CCONJ
admet-2088	649	43	ir768	ir768	NOUN
admet-2088	649	44	triggered	trigger	VERB
admet-2088	649	45	synergistic	synergistic	ADJ
admet-2088	649	46	anticancer	anticancer	NOUN
admet-2088	649	47	effect	effect	NOUN
admet-2088	649	48	in	in	ADP
admet-2088	649	49	melanoma	melanoma	NOUN
admet-2088	649	50	cells	cell	NOUN
admet-2088	649	51	[	[	X
admet-2088	649	52	192	192	NUM
admet-2088	649	53	]	]	SYM
admet-2088	649	54	nanogel	nanogel	NOUN
admet-2088	649	55	nanogel	nanogel	NOUN
admet-2088	649	56	gox	gox	PROPN
admet-2088	649	57	fbma	fbma	PROPN
admet-2088	649	58	and	and	CCONJ
admet-2088	649	59	oegma	oegma	ADJ
admet-2088	649	60	(	(	PUNCT
admet-2088	649	61	poly(fbma	poly(fbma	PROPN
admet-2088	649	62	-	-	PUNCT
admet-2088	649	63	cooegma	cooegma	NOUN
admet-2088	649	64	)	)	PUNCT
admet-2088	649	65	improved	improve	VERB
admet-2088	649	66	antimelanoma	antimelanoma	ADJ
admet-2088	649	67	efficacy	efficacy	NOUN
admet-2088	649	68	without	without	ADP
admet-2088	649	69	systemic	systemic	ADJ
admet-2088	649	70	toxicity	toxicity	NOUN
admet-2088	649	71	due	due	ADP
admet-2088	649	72	to	to	ADP
admet-2088	649	73	the	the	DET
admet-2088	649	74	confinement	confinement	NOUN
admet-2088	649	75	of	of	ADP
admet-2088	649	76	gox	gox	PROPN
admet-2088	649	77	to	to	ADP
admet-2088	649	78	only	only	ADV
admet-2088	649	79	tumour	tumour	PRON
admet-2088	649	80	region	region	NOUN
admet-2088	649	81	[	[	X
admet-2088	649	82	197	197	NUM
admet-2088	649	83	]	]	PUNCT
admet-2088	649	84	thermosensitive	thermosensitive	ADJ
admet-2088	649	85	nano	nano	NOUN
admet-2088	649	86	-	-	PUNCT
admet-2088	649	87	hydrogel	hydrogel	NOUN
admet-2088	649	88	pp	pp	PROPN
admet-2088	649	89	-	-	PUNCT
admet-2088	649	90	nps	nps	PROPN
admet-2088	649	91	containing	contain	VERB
admet-2088	649	92	deferasirox	deferasirox	NOUN
admet-2088	649	93	agarose	agarose	NOUN
admet-2088	649	94	and	and	CCONJ
admet-2088	649	95	tmpooxidized	tmpooxidize	VERB
admet-2088	649	96	lignocellulose	lignocellulose	VERB
admet-2088	649	97	dose	dose	NOUN
admet-2088	649	98	-	-	PUNCT
admet-2088	649	99	dependent	dependent	ADJ
admet-2088	649	100	cytotoxicity	cytotoxicity	NOUN
admet-2088	649	101	[	[	X
admet-2088	649	102	198	198	NUM
admet-2088	649	103	]	]	PUNCT
admet-2088	649	104	liposomes	liposome	NOUN
admet-2088	649	105	liposomes	liposome	NOUN
admet-2088	650	1	+	+	CCONJ
admet-2088	650	2	vaccines	vaccine	NOUN
admet-2088	650	3	celecoxib	celecoxib	VERB
admet-2088	650	4	dendritic	dendritic	ADJ
admet-2088	650	5	cell	cell	NOUN
admet-2088	650	6	vaccines	vaccine	NOUN
admet-2088	650	7	pulsed	pulse	VERB
admet-2088	650	8	with	with	ADP
admet-2088	650	9	gp100	gp100	PROPN
admet-2088	650	10	peptide	peptide	VERB
admet-2088	650	11	tumour	tumour	NOUN
admet-2088	650	12	growth	growth	NOUN
admet-2088	650	13	inhibition	inhibition	NOUN
admet-2088	650	14	and	and	CCONJ
admet-2088	650	15	overall	overall	ADJ
admet-2088	650	16	survival	survival	NOUN
admet-2088	651	1	[	[	X
admet-2088	651	2	207	207	NUM
admet-2088	651	3	]	]	X
admet-2088	651	4	chitosan	chitosan	NOUN
admet-2088	651	5	coated	coat	VERB
admet-2088	651	6	liposomes	liposome	NOUN
admet-2088	651	7	indocyanine	indocyanine	PROPN
admet-2088	651	8	green	green	PROPN
admet-2088	651	9	chitosan	chitosan	PROPN
admet-2088	651	10	higher	high	ADJ
admet-2088	651	11	cellular	cellular	ADJ
admet-2088	651	12	uptake	uptake	NOUN
admet-2088	651	13	and	and	CCONJ
admet-2088	651	14	photocytotoxicity	photocytotoxicity	NOUN
admet-2088	651	15	of	of	ADP
admet-2088	651	16	melanoma	melanoma	NOUN
admet-2088	651	17	cells	cell	NOUN
admet-2088	651	18	due	due	ADJ
admet-2088	651	19	to	to	ADP
admet-2088	651	20	high	high	ADJ
admet-2088	651	21	skin	skin	NOUN
admet-2088	651	22	permeability	permeability	NOUN
admet-2088	651	23	[	[	X
admet-2088	651	24	208	208	NUM
admet-2088	651	25	]	]	X
admet-2088	651	26	ha	ha	ADJ
admet-2088	651	27	-	-	PUNCT
admet-2088	651	28	coated	coated	ADJ
admet-2088	651	29	liposomes	liposome	NOUN
admet-2088	651	30	dacarbazine	dacarbazine	NOUN
admet-2088	651	31	and	and	CCONJ
admet-2088	651	32	eugenol	eugenol	NOUN
admet-2088	651	33	ha	ha	INTJ
admet-2088	651	34	higher	high	ADJ
admet-2088	651	35	cytotoxicity	cytotoxicity	NOUN
admet-2088	651	36	against	against	ADP
admet-2088	651	37	melanoma	melanoma	NOUN
admet-2088	651	38	cells	cell	NOUN
admet-2088	651	39	along	along	ADP
admet-2088	651	40	with	with	ADP
admet-2088	651	41	significantly	significantly	ADV
admet-2088	651	42	higher	high	ADJ
admet-2088	651	43	inhibition	inhibition	NOUN
admet-2088	651	44	of	of	ADP
admet-2088	651	45	cell	cell	NOUN
admet-2088	651	46	migration	migration	NOUN
admet-2088	651	47	and	and	CCONJ
admet-2088	651	48	proliferation	proliferation	NOUN
admet-2088	651	49	[	[	X
admet-2088	651	50	209	209	NUM
admet-2088	651	51	]	]	X
admet-2088	651	52	as1411	as1411	NOUN
admet-2088	651	53	aptamer	aptamer	NOUN
admet-2088	651	54	functionalized	functionalize	VERB
admet-2088	651	55	liposomes	liposome	NOUN
admet-2088	651	56	5	5	NUM
admet-2088	651	57	-	-	PUNCT
admet-2088	651	58	fluorouracil	fluorouracil	NOUN
admet-2088	651	59	as1411	as1411	NOUN
admet-2088	651	60	aptamer	aptamer	NOUN
admet-2088	651	61	higher	high	ADJ
admet-2088	651	62	efficiency	efficiency	NOUN
admet-2088	651	63	in	in	ADP
admet-2088	651	64	terms	term	NOUN
admet-2088	651	65	of	of	ADP
admet-2088	651	66	in	in	ADP
admet-2088	651	67	vitro	vitro	X
admet-2088	651	68	cell	cell	NOUN
admet-2088	651	69	viability	viability	NOUN
admet-2088	651	70	,	,	PUNCT
admet-2088	651	71	apoptotic	apoptotic	ADJ
admet-2088	651	72	effects	effect	NOUN
admet-2088	651	73	and	and	CCONJ
admet-2088	651	74	targeting	target	VERB
admet-2088	651	75	capability	capability	NOUN
admet-2088	651	76	[	[	X
admet-2088	651	77	210	210	NUM
admet-2088	651	78	]	]	SYM
admet-2088	651	79	tool	tool	NOUN
admet-2088	651	80	to	to	PART
admet-2088	651	81	enrich	enrich	VERB
admet-2088	651	82	the	the	DET
admet-2088	651	83	blood	blood	NOUN
admet-2088	651	84	proteomic	proteomic	ADJ
admet-2088	651	85	analysis	analysis	NOUN
admet-2088	651	86	[	[	X
admet-2088	651	87	211	211	NUM
admet-2088	651	88	]	]	PUNCT
admet-2088	651	89	niosomes	niosome	VERB
admet-2088	651	90	5	5	NUM
admet-2088	651	91	-	-	PUNCT
admet-2088	651	92	fluorouracil	fluorouracil	NOUN
admet-2088	651	93	improved	improve	VERB
admet-2088	651	94	the	the	DET
admet-2088	651	95	stability	stability	NOUN
admet-2088	651	96	and	and	CCONJ
admet-2088	651	97	enhanced	enhance	VERB
admet-2088	651	98	the	the	DET
admet-2088	651	99	skin	skin	NOUN
admet-2088	651	100	permeation	permeation	NOUN
admet-2088	651	101	ability	ability	NOUN
admet-2088	651	102	[	[	X
admet-2088	651	103	214	214	NUM
admet-2088	651	104	]	]	PUNCT
admet-2088	651	105	ethosomes	ethosome	NOUN
admet-2088	651	106	and	and	CCONJ
admet-2088	651	107	transferosome	transferosome	ADJ
admet-2088	651	108	sulforaphane	sulforaphane	NOUN
admet-2088	651	109	higher	high	ADJ
admet-2088	651	110	skin	skin	NOUN
admet-2088	651	111	permeability	permeability	NOUN
admet-2088	651	112	and	and	CCONJ
admet-2088	651	113	improved	improved	ADJ
admet-2088	651	114	anticancer	anticancer	NOUN
admet-2088	651	115	activity	activity	NOUN
admet-2088	651	116	due	due	ADP
admet-2088	651	117	to	to	ADP
admet-2088	651	118	antiproliferative	antiproliferative	ADJ
admet-2088	651	119	activity	activity	NOUN
admet-2088	651	120	[	[	X
admet-2088	651	121	215	215	NUM
admet-2088	651	122	]	]	PUNCT
admet-2088	651	123	slns	slns	PROPN
admet-2088	651	124	4nc	4nc	NOUN
admet-2088	651	125	and	and	CCONJ
admet-2088	651	126	detc	detc	NOUN
admet-2088	651	127	beeswax	beeswax	NOUN
admet-2088	651	128	higher	high	ADJ
admet-2088	651	129	cytotoxicity	cytotoxicity	NOUN
admet-2088	651	130	reduces	reduce	VERB
admet-2088	651	131	cell	cell	NOUN
admet-2088	651	132	viability	viability	NOUN
admet-2088	652	1	[	[	X
admet-2088	652	2	11	11	NUM
admet-2088	652	3	]	]	PUNCT
admet-2088	652	4	exosomes	exosome	VERB
admet-2088	652	5	ir	ir	NOUN
admet-2088	652	6	-	-	NOUN
admet-2088	652	7	fe@exo	fe@exo	NOUN
admet-2088	652	8	ir	ir	PROPN
admet-2088	652	9	-	-	PUNCT
admet-2088	652	10	fe	fe	X
admet-2088	652	11	nps	nps	PROPN
admet-2088	652	12	camouflage	camouflage	NOUN
admet-2088	652	13	with	with	ADP
admet-2088	652	14	melanoma	melanoma	NOUN
admet-2088	652	15	exosomes	exosome	NOUN
admet-2088	652	16	full	full	ADJ
admet-2088	652	17	eradication	eradication	NOUN
admet-2088	652	18	of	of	ADP
admet-2088	652	19	melanoma	melanoma	NOUN
admet-2088	652	20	tumour	tumour	NOUN
admet-2088	652	21	with	with	ADP
admet-2088	652	22	single	single	ADJ
admet-2088	652	23	treatment	treatment	NOUN
admet-2088	652	24	and	and	CCONJ
admet-2088	652	25	prevent	prevent	VERB
admet-2088	652	26	the	the	DET
admet-2088	652	27	metastasis	metastasis	NOUN
admet-2088	652	28	[	[	X
admet-2088	652	29	229	229	NUM
admet-2088	652	30	]	]	PUNCT
admet-2088	652	31	gene	gene	NOUN
admet-2088	652	32	therapy	therapy	NOUN
admet-2088	652	33	nanoworm	nanoworm	PROPN
admet-2088	652	34	sirna	sirna	PROPN
admet-2088	652	35	(	(	PUNCT
admet-2088	652	36	sisuvivin	sisuvivin	PROPN
admet-2088	652	37	)	)	PUNCT
admet-2088	652	38	nanoerythrocytes	nanoerythrocyte	NOUN
admet-2088	652	39	protects	protect	VERB
admet-2088	652	40	sirna	sirna	PROPN
admet-2088	652	41	and	and	CCONJ
admet-2088	652	42	superior	superior	ADJ
admet-2088	652	43	antimelanoma	antimelanoma	ADJ
admet-2088	652	44	effect	effect	NOUN
admet-2088	653	1	[	[	X
admet-2088	653	2	232	232	NUM
admet-2088	653	3	]	]	SYM
admet-2088	653	4	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	653	5	m.	m.	NOUN
admet-2088	653	6	kulkarni	kulkarni	PROPN
admet-2088	653	7	et	et	PROPN
admet-2088	653	8	al	al	PROPN
admet-2088	653	9	.	.	PROPN
admet-2088	653	10	admet	admet	PROPN
admet-2088	653	11	&	&	CCONJ
admet-2088	653	12	dmpk	dmpk	PROPN
admet-2088	653	13	12(1	12(1	PROPN
admet-2088	653	14	)	)	PUNCT
admet-2088	653	15	(	(	PUNCT
admet-2088	653	16	2024	2024	NUM
admet-2088	653	17	)	)	PUNCT
admet-2088	653	18	107	107	NUM
admet-2088	653	19	-	-	SYM
admet-2088	653	20	150	150	NUM
admet-2088	653	21	134	134	NUM
admet-2088	653	22	conclusions	conclusion	NOUN
admet-2088	653	23	the	the	DET
admet-2088	653	24	last	last	ADJ
admet-2088	653	25	few	few	ADJ
admet-2088	653	26	decades	decade	NOUN
admet-2088	653	27	have	have	AUX
admet-2088	653	28	witnessed	witness	VERB
admet-2088	653	29	extraordinary	extraordinary	ADJ
admet-2088	653	30	progress	progress	NOUN
admet-2088	653	31	in	in	ADP
admet-2088	653	32	the	the	DET
admet-2088	653	33	development	development	NOUN
admet-2088	653	34	of	of	ADP
admet-2088	653	35	materials	material	NOUN
admet-2088	653	36	that	that	PRON
admet-2088	653	37	are	be	AUX
admet-2088	653	38	oriented	orient	VERB
admet-2088	653	39	towards	towards	ADP
admet-2088	653	40	melanoma	melanoma	NOUN
admet-2088	653	41	therapy	therapy	NOUN
admet-2088	653	42	.	.	PUNCT
admet-2088	654	1	the	the	DET
admet-2088	654	2	most	most	ADV
admet-2088	654	3	important	important	ADJ
admet-2088	654	4	benefit	benefit	NOUN
admet-2088	654	5	of	of	ADP
admet-2088	654	6	nms	nms	NOUN
admet-2088	654	7	is	be	AUX
admet-2088	654	8	that	that	SCONJ
admet-2088	654	9	they	they	PRON
admet-2088	654	10	can	can	AUX
admet-2088	654	11	not	not	PART
admet-2088	654	12	only	only	ADV
admet-2088	654	13	be	be	AUX
admet-2088	654	14	directly	directly	ADV
admet-2088	654	15	delivered	deliver	VERB
admet-2088	654	16	to	to	PART
admet-2088	654	17	treat	treat	VERB
admet-2088	654	18	melanoma	melanoma	NOUN
admet-2088	654	19	but	but	CCONJ
admet-2088	654	20	also	also	ADV
admet-2088	654	21	can	can	AUX
admet-2088	654	22	carry	carry	VERB
admet-2088	654	23	and	and	CCONJ
admet-2088	654	24	deliver	deliver	VERB
admet-2088	654	25	other	other	ADJ
admet-2088	654	26	therapeutic	therapeutic	ADJ
admet-2088	654	27	agents	agent	NOUN
admet-2088	654	28	to	to	PART
admet-2088	654	29	achieve	achieve	VERB
admet-2088	654	30	better	well	ADJ
admet-2088	654	31	or	or	CCONJ
admet-2088	654	32	synergistic	synergistic	ADJ
admet-2088	654	33	therapeutic	therapeutic	ADJ
admet-2088	654	34	effects	effect	NOUN
admet-2088	654	35	.	.	PUNCT
admet-2088	655	1	nm	nm	ADV
admet-2088	655	2	-	-	PUNCT
admet-2088	655	3	based	base	VERB
admet-2088	655	4	dds	dds	PROPN
admet-2088	655	5	or	or	CCONJ
admet-2088	655	6	nanomedicine	nanomedicine	NOUN
admet-2088	655	7	has	have	AUX
admet-2088	655	8	opened	open	VERB
admet-2088	655	9	new	new	ADJ
admet-2088	655	10	avenues	avenue	NOUN
admet-2088	655	11	in	in	ADP
admet-2088	655	12	the	the	DET
admet-2088	655	13	therapeutic	therapeutic	ADJ
admet-2088	655	14	management	management	NOUN
admet-2088	655	15	of	of	ADP
admet-2088	655	16	complex	complex	ADJ
admet-2088	655	17	diseases	disease	NOUN
admet-2088	655	18	such	such	ADJ
admet-2088	655	19	as	as	ADP
admet-2088	655	20	melanoma	melanoma	NOUN
admet-2088	655	21	skin	skin	NOUN
admet-2088	655	22	cancer	cancer	NOUN
admet-2088	655	23	.	.	PUNCT
admet-2088	656	1	recently	recently	ADV
admet-2088	656	2	,	,	PUNCT
admet-2088	656	3	successful	successful	ADJ
admet-2088	656	4	and	and	CCONJ
admet-2088	656	5	encouraging	encourage	VERB
admet-2088	656	6	results	result	NOUN
admet-2088	656	7	from	from	ADP
admet-2088	656	8	the	the	DET
admet-2088	656	9	preclinical	preclinical	ADJ
admet-2088	656	10	and	and	CCONJ
admet-2088	656	11	clinical	clinical	ADJ
admet-2088	656	12	investigations	investigation	NOUN
admet-2088	656	13	brought	bring	VERB
admet-2088	656	14	hope	hope	NOUN
admet-2088	656	15	in	in	ADP
admet-2088	656	16	the	the	DET
admet-2088	656	17	anticipated	anticipated	ADJ
admet-2088	656	18	direction	direction	NOUN
admet-2088	656	19	.	.	PUNCT
admet-2088	657	1	despite	despite	SCONJ
admet-2088	657	2	the	the	DET
admet-2088	657	3	fact	fact	NOUN
admet-2088	657	4	that	that	SCONJ
admet-2088	657	5	nanotherapeutics	nanotherapeutic	NOUN
admet-2088	657	6	have	have	AUX
admet-2088	657	7	come	come	VERB
admet-2088	657	8	a	a	DET
admet-2088	657	9	long	long	ADJ
admet-2088	657	10	way	way	NOUN
admet-2088	657	11	in	in	ADP
admet-2088	657	12	significant	significant	ADJ
admet-2088	657	13	anti	anti	ADJ
admet-2088	657	14	-	-	ADJ
admet-2088	657	15	melanoma	melanoma	ADJ
admet-2088	657	16	therapy	therapy	NOUN
admet-2088	657	17	,	,	PUNCT
admet-2088	657	18	undoubtedly	undoubtedly	ADV
admet-2088	657	19	,	,	PUNCT
admet-2088	657	20	there	there	PRON
admet-2088	657	21	exist	exist	VERB
admet-2088	657	22	a	a	DET
admet-2088	657	23	few	few	ADJ
admet-2088	657	24	key	key	ADJ
admet-2088	657	25	issues	issue	NOUN
admet-2088	657	26	,	,	PUNCT
admet-2088	657	27	such	such	ADJ
admet-2088	657	28	as	as	ADP
admet-2088	657	29	the	the	DET
admet-2088	657	30	requirement	requirement	NOUN
admet-2088	657	31	of	of	ADP
admet-2088	657	32	high	high	ADJ
admet-2088	657	33	initial	initial	ADJ
admet-2088	657	34	investment	investment	NOUN
admet-2088	657	35	,	,	PUNCT
admet-2088	657	36	scalability	scalability	NOUN
admet-2088	657	37	,	,	PUNCT
admet-2088	657	38	safety	safety	NOUN
admet-2088	657	39	(	(	PUNCT
admet-2088	657	40	toxicity	toxicity	NOUN
admet-2088	657	41	)	)	PUNCT
admet-2088	657	42	,	,	PUNCT
admet-2088	657	43	purity	purity	NOUN
admet-2088	657	44	,	,	PUNCT
admet-2088	657	45	lack	lack	NOUN
admet-2088	657	46	of	of	ADP
admet-2088	657	47	proper	proper	ADJ
admet-2088	657	48	guidelines	guideline	NOUN
admet-2088	657	49	(	(	PUNCT
admet-2088	657	50	nano	nano	NOUN
admet-2088	657	51	guidelines	guideline	NOUN
admet-2088	657	52	)	)	PUNCT
admet-2088	657	53	,	,	PUNCT
admet-2088	657	54	and	and	CCONJ
admet-2088	657	55	more	more	ADV
admet-2088	657	56	importantly	importantly	ADV
admet-2088	657	57	lack	lack	NOUN
admet-2088	657	58	of	of	ADP
admet-2088	657	59	good	good	ADJ
admet-2088	657	60	in	in	NOUN
admet-2088	657	61	-	-	PUNCT
admet-2088	657	62	vitro	vitro	X
admet-2088	657	63	and	and	CCONJ
admet-2088	657	64	pre	pre	ADJ
admet-2088	657	65	-	-	ADJ
admet-2088	657	66	clinical	clinical	ADJ
admet-2088	657	67	melanoma	melanoma	NOUN
admet-2088	657	68	models	model	NOUN
admet-2088	657	69	.	.	PUNCT
admet-2088	658	1	the	the	DET
admet-2088	658	2	main	main	ADJ
admet-2088	658	3	starting	starting	NOUN
admet-2088	658	4	issue	issue	NOUN
admet-2088	658	5	for	for	ADP
admet-2088	658	6	pharmaceutical	pharmaceutical	ADJ
admet-2088	658	7	companies	company	NOUN
admet-2088	658	8	in	in	ADP
admet-2088	658	9	the	the	DET
admet-2088	658	10	development	development	NOUN
admet-2088	658	11	of	of	ADP
admet-2088	658	12	nanomedicine	nanomedicine	NOUN
admet-2088	658	13	for	for	ADP
admet-2088	658	14	melanoma	melanoma	NOUN
admet-2088	658	15	is	be	AUX
admet-2088	658	16	the	the	DET
admet-2088	658	17	high	high	ADJ
admet-2088	658	18	capital	capital	NOUN
admet-2088	658	19	investment	investment	NOUN
admet-2088	658	20	coupled	couple	VERB
admet-2088	658	21	with	with	ADP
admet-2088	658	22	the	the	DET
admet-2088	658	23	fear	fear	NOUN
admet-2088	658	24	of	of	ADP
admet-2088	658	25	failure	failure	NOUN
admet-2088	658	26	in	in	ADP
admet-2088	658	27	the	the	DET
admet-2088	658	28	return	return	NOUN
admet-2088	658	29	of	of	ADP
admet-2088	658	30	investment	investment	NOUN
admet-2088	658	31	[	[	X
admet-2088	658	32	233	233	NUM
admet-2088	658	33	]	]	PUNCT
admet-2088	658	34	.	.	PUNCT
admet-2088	659	1	the	the	DET
admet-2088	659	2	batchto	batchto	NOUN
admet-2088	659	3	-	-	PUNCT
admet-2088	659	4	batch	batch	NOUN
admet-2088	659	5	variation	variation	NOUN
admet-2088	659	6	after	after	ADP
admet-2088	659	7	manufacturing	manufacturing	NOUN
admet-2088	659	8	of	of	ADP
admet-2088	659	9	nanomedicine	nanomedicine	NOUN
admet-2088	659	10	is	be	AUX
admet-2088	659	11	critical	critical	ADJ
admet-2088	659	12	due	due	ADP
admet-2088	659	13	to	to	ADP
admet-2088	659	14	the	the	DET
admet-2088	659	15	complex	complex	ADJ
admet-2088	659	16	nature	nature	NOUN
admet-2088	659	17	of	of	ADP
admet-2088	659	18	quality	quality	NOUN
admet-2088	659	19	control	control	NOUN
admet-2088	659	20	they	they	PRON
admet-2088	659	21	undergo	undergo	VERB
admet-2088	659	22	compared	compare	VERB
admet-2088	659	23	to	to	ADP
admet-2088	659	24	conventional	conventional	ADJ
admet-2088	659	25	dosage	dosage	NOUN
admet-2088	659	26	forms	form	NOUN
admet-2088	659	27	.	.	PUNCT
admet-2088	660	1	the	the	DET
admet-2088	660	2	transition	transition	NOUN
admet-2088	660	3	from	from	ADP
admet-2088	660	4	laboratory	laboratory	NOUN
admet-2088	660	5	scale	scale	NOUN
admet-2088	660	6	to	to	ADP
admet-2088	660	7	industrial	industrial	ADJ
admet-2088	660	8	scale	scale	NOUN
admet-2088	660	9	is	be	AUX
admet-2088	660	10	also	also	ADV
admet-2088	660	11	challenging	challenge	VERB
admet-2088	660	12	because	because	SCONJ
admet-2088	660	13	of	of	ADP
admet-2088	660	14	the	the	DET
admet-2088	660	15	requirement	requirement	NOUN
admet-2088	660	16	of	of	ADP
admet-2088	660	17	a	a	DET
admet-2088	660	18	lot	lot	NOUN
admet-2088	660	19	of	of	ADP
admet-2088	660	20	effort	effort	NOUN
admet-2088	660	21	per	per	ADP
admet-2088	660	22	stability	stability	NOUN
admet-2088	660	23	and	and	CCONJ
admet-2088	660	24	optimization	optimization	NOUN
admet-2088	660	25	.	.	PUNCT
admet-2088	661	1	however	however	ADV
admet-2088	661	2	,	,	PUNCT
admet-2088	661	3	the	the	DET
admet-2088	661	4	invention	invention	NOUN
admet-2088	661	5	of	of	ADP
admet-2088	661	6	the	the	DET
admet-2088	661	7	microfluidic	microfluidic	ADJ
admet-2088	661	8	technique	technique	NOUN
admet-2088	661	9	could	could	AUX
admet-2088	661	10	streamline	streamline	VERB
admet-2088	661	11	the	the	DET
admet-2088	661	12	scalability	scalability	NOUN
admet-2088	661	13	issue	issue	NOUN
admet-2088	661	14	[	[	X
admet-2088	661	15	234	234	NUM
admet-2088	661	16	]	]	PUNCT
admet-2088	661	17	.	.	PUNCT
admet-2088	662	1	the	the	DET
admet-2088	662	2	safety	safety	NOUN
admet-2088	662	3	of	of	ADP
admet-2088	662	4	the	the	DET
admet-2088	662	5	nms	nms	NOUN
admet-2088	662	6	is	be	AUX
admet-2088	662	7	also	also	ADV
admet-2088	662	8	very	very	ADV
admet-2088	662	9	crucial	crucial	ADJ
admet-2088	662	10	during	during	ADP
admet-2088	662	11	the	the	DET
admet-2088	662	12	development	development	NOUN
admet-2088	662	13	of	of	ADP
admet-2088	662	14	nanotherapeutics	nanotherapeutic	NOUN
admet-2088	662	15	.	.	PUNCT
admet-2088	663	1	some	some	DET
admet-2088	663	2	inorganic	inorganic	ADJ
admet-2088	663	3	nms	nms	NOUN
admet-2088	663	4	demonstrated	demonstrate	VERB
admet-2088	663	5	long	long	ADJ
admet-2088	663	6	-	-	PUNCT
admet-2088	663	7	term	term	NOUN
admet-2088	663	8	toxicities	toxicity	NOUN
admet-2088	663	9	and	and	CCONJ
admet-2088	663	10	issues	issue	NOUN
admet-2088	663	11	related	relate	VERB
admet-2088	663	12	to	to	ADP
admet-2088	663	13	biodegradability	biodegradability	NOUN
admet-2088	663	14	.	.	PUNCT
admet-2088	664	1	it	it	PRON
admet-2088	664	2	is	be	AUX
admet-2088	664	3	evident	evident	ADJ
admet-2088	664	4	from	from	ADP
admet-2088	664	5	the	the	DET
admet-2088	664	6	cytotoxicity	cytotoxicity	NOUN
admet-2088	664	7	caused	cause	VERB
admet-2088	664	8	by	by	ADP
admet-2088	664	9	dendrimer	dendrimer	NOUN
admet-2088	664	10	.	.	PUNCT
admet-2088	665	1	apart	apart	ADV
admet-2088	665	2	from	from	ADP
admet-2088	665	3	nms	nms	PROPN
admet-2088	665	4	,	,	PUNCT
admet-2088	665	5	the	the	DET
admet-2088	665	6	excipients	excipient	NOUN
admet-2088	665	7	used	use	VERB
admet-2088	665	8	in	in	ADP
admet-2088	665	9	the	the	DET
admet-2088	665	10	preparation	preparation	NOUN
admet-2088	665	11	of	of	ADP
admet-2088	665	12	nanotherapeutics	nanotherapeutic	NOUN
admet-2088	665	13	,	,	PUNCT
admet-2088	665	14	including	include	VERB
admet-2088	665	15	emulsifiers	emulsifier	NOUN
admet-2088	665	16	,	,	PUNCT
admet-2088	665	17	solvents	solvent	NOUN
admet-2088	665	18	like	like	ADP
admet-2088	665	19	alcohol	alcohol	NOUN
admet-2088	665	20	,	,	PUNCT
admet-2088	665	21	and	and	CCONJ
admet-2088	665	22	edge	edge	NOUN
admet-2088	665	23	activators	activator	NOUN
admet-2088	665	24	,	,	PUNCT
admet-2088	665	25	have	have	VERB
admet-2088	665	26	the	the	DET
admet-2088	665	27	potential	potential	NOUN
admet-2088	665	28	to	to	PART
admet-2088	665	29	cause	cause	VERB
admet-2088	665	30	skin	skin	NOUN
admet-2088	665	31	irritation	irritation	NOUN
admet-2088	665	32	and	and	CCONJ
admet-2088	665	33	toxicity	toxicity	NOUN
admet-2088	665	34	.	.	PUNCT
admet-2088	666	1	the	the	DET
admet-2088	666	2	regulatory	regulatory	ADJ
admet-2088	666	3	landscapes	landscape	NOUN
admet-2088	666	4	for	for	ADP
admet-2088	666	5	nm	nm	ADV
admet-2088	666	6	-	-	PUNCT
admet-2088	666	7	based	base	VERB
admet-2088	666	8	dds	dds	PROPN
admet-2088	666	9	are	be	AUX
admet-2088	666	10	still	still	ADV
admet-2088	666	11	in	in	ADP
admet-2088	666	12	the	the	DET
admet-2088	666	13	infancy	infancy	NOUN
admet-2088	666	14	stage	stage	NOUN
admet-2088	666	15	,	,	PUNCT
admet-2088	666	16	necessitating	necessitate	VERB
admet-2088	666	17	urgent	urgent	ADJ
admet-2088	666	18	reform	reform	NOUN
admet-2088	666	19	.	.	PUNCT
admet-2088	667	1	in	in	ADP
admet-2088	667	2	this	this	DET
admet-2088	667	3	context	context	NOUN
admet-2088	667	4	,	,	PUNCT
admet-2088	667	5	it	it	PRON
admet-2088	667	6	can	can	AUX
admet-2088	667	7	be	be	AUX
admet-2088	667	8	more	more	ADV
admet-2088	667	9	appropriate	appropriate	ADJ
admet-2088	667	10	to	to	PART
admet-2088	667	11	develop	develop	VERB
admet-2088	667	12	‘	'	PUNCT
admet-2088	667	13	nanoguidelines	nanoguideline	NOUN
admet-2088	667	14	”	"	PUNCT
admet-2088	667	15	that	that	PRON
admet-2088	667	16	will	will	AUX
admet-2088	667	17	erase	erase	VERB
admet-2088	667	18	the	the	DET
admet-2088	667	19	uncertainty	uncertainty	NOUN
admet-2088	667	20	among	among	ADP
admet-2088	667	21	investors	investor	NOUN
admet-2088	667	22	and	and	CCONJ
admet-2088	667	23	the	the	DET
admet-2088	667	24	pharma	pharma	PROPN
admet-2088	667	25	industry	industry	NOUN
admet-2088	667	26	[	[	X
admet-2088	667	27	233	233	NUM
admet-2088	667	28	]	]	PUNCT
admet-2088	667	29	.	.	PUNCT
admet-2088	668	1	for	for	ADP
admet-2088	668	2	the	the	DET
admet-2088	668	3	successful	successful	ADJ
admet-2088	668	4	launch	launch	NOUN
admet-2088	668	5	of	of	ADP
admet-2088	668	6	nanomedicines	nanomedicine	NOUN
admet-2088	668	7	,	,	PUNCT
admet-2088	668	8	proper	proper	ADJ
admet-2088	668	9	in	in	ADV
admet-2088	668	10	-	-	PUNCT
admet-2088	668	11	vitro	vitro	X
admet-2088	668	12	,	,	PUNCT
admet-2088	668	13	preclinical	preclinical	ADJ
admet-2088	668	14	and	and	CCONJ
admet-2088	668	15	clinical	clinical	ADJ
admet-2088	668	16	models	model	NOUN
admet-2088	668	17	are	be	AUX
admet-2088	668	18	desired	desire	VERB
admet-2088	668	19	.	.	PUNCT
admet-2088	669	1	for	for	ADP
admet-2088	669	2	example	example	NOUN
admet-2088	669	3	,	,	PUNCT
admet-2088	669	4	human	human	NOUN
admet-2088	669	5	-	-	PUNCT
admet-2088	669	6	specific	specific	ADJ
admet-2088	669	7	and	and	CCONJ
admet-2088	669	8	physiologically	physiologically	ADV
admet-2088	669	9	relevant	relevant	ADJ
admet-2088	669	10	models	model	NOUN
admet-2088	669	11	such	such	ADJ
admet-2088	669	12	as	as	ADP
admet-2088	669	13	3d	3d	PROPN
admet-2088	669	14	spheroids	spheroid	NOUN
admet-2088	669	15	-	-	PUNCT
admet-2088	669	16	based	base	VERB
admet-2088	669	17	models	model	NOUN
admet-2088	669	18	and	and	CCONJ
admet-2088	669	19	human	human	ADJ
admet-2088	669	20	skin	skin	NOUN
admet-2088	669	21	equivalent	equivalent	ADJ
admet-2088	669	22	models	model	NOUN
admet-2088	669	23	are	be	AUX
admet-2088	669	24	better	well	ADJ
admet-2088	669	25	predictors	predictor	NOUN
admet-2088	669	26	of	of	ADP
admet-2088	669	27	in	in	ADP
admet-2088	669	28	-	-	PUNCT
admet-2088	669	29	vivo	vivo	NOUN
admet-2088	669	30	models	model	NOUN
admet-2088	669	31	.	.	PUNCT
admet-2088	670	1	despite	despite	SCONJ
admet-2088	670	2	all	all	DET
admet-2088	670	3	these	these	PRON
admet-2088	670	4	,	,	PUNCT
admet-2088	670	5	it	it	PRON
admet-2088	670	6	is	be	AUX
admet-2088	670	7	believed	believe	VERB
admet-2088	670	8	that	that	SCONJ
admet-2088	670	9	with	with	ADP
admet-2088	670	10	the	the	DET
admet-2088	670	11	continuous	continuous	ADJ
admet-2088	670	12	development	development	NOUN
admet-2088	670	13	in	in	ADP
admet-2088	670	14	nanotechnology	nanotechnology	NOUN
admet-2088	670	15	and	and	CCONJ
admet-2088	670	16	nm	nm	ADV
admet-2088	670	17	-	-	PUNCT
admet-2088	670	18	based	base	VERB
admet-2088	670	19	dds	dds	PROPN
admet-2088	670	20	,	,	PUNCT
admet-2088	670	21	the	the	DET
admet-2088	670	22	challenges	challenge	NOUN
admet-2088	670	23	will	will	AUX
admet-2088	670	24	be	be	AUX
admet-2088	670	25	addressed	address	VERB
admet-2088	670	26	in	in	ADP
admet-2088	670	27	the	the	DET
admet-2088	670	28	foreseeable	foreseeable	ADJ
admet-2088	670	29	future	future	NOUN
admet-2088	670	30	,	,	PUNCT
admet-2088	670	31	which	which	PRON
admet-2088	670	32	will	will	AUX
admet-2088	670	33	pave	pave	VERB
admet-2088	670	34	the	the	DET
admet-2088	670	35	path	path	NOUN
admet-2088	670	36	for	for	ADP
admet-2088	670	37	the	the	DET
admet-2088	670	38	better	well	ADJ
admet-2088	670	39	management	management	NOUN
admet-2088	670	40	of	of	ADP
admet-2088	670	41	dreaded	dread	VERB
admet-2088	670	42	diseases	disease	NOUN
admet-2088	670	43	such	such	ADJ
admet-2088	670	44	as	as	ADP
admet-2088	670	45	skin	skin	NOUN
admet-2088	670	46	melanoma	melanoma	NOUN
admet-2088	670	47	.	.	PUNCT
admet-2088	671	1	abbreviations	abbreviation	NOUN
admet-2088	671	2	drug	drug	NOUN
admet-2088	671	3	delivery	delivery	NOUN
admet-2088	671	4	system	system	NOUN
admet-2088	671	5	.........................................	.........................................	PUNCT
admet-2088	672	1	dds	dds	PROPN
admet-2088	672	2	ultraviolet	ultraviolet	PROPN
admet-2088	672	3	..........................................................	..........................................................	PUNCT
admet-2088	673	1	uv	uv	NOUN
admet-2088	673	2	v	v	NOUN
admet-2088	673	3	-	-	PUNCT
admet-2088	673	4	raf	raf	NOUN
admet-2088	673	5	murine	murine	ADJ
admet-2088	673	6	sarcoma	sarcoma	NOUN
admet-2088	673	7	viral	viral	ADJ
admet-2088	673	8	oncogene	oncogene	NOUN
admet-2088	673	9	homolog	homolog	NOUN
admet-2088	673	10	b1	b1	PROPN
admet-2088	673	11	........................................	........................................	PUNCT
admet-2088	673	12	braf	braf	NOUN
admet-2088	673	13	neuroblastoma	neuroblastoma	NOUN
admet-2088	673	14	ras	ras	X
admet-2088	673	15	viral	viral	ADJ
admet-2088	673	16	oncogene	oncogene	NOUN
admet-2088	673	17	homolog	homolog	NOUN
admet-2088	673	18	....	....	PUNCT
admet-2088	674	1	nras	nras	PROPN
admet-2088	674	2	nuclear	nuclear	ADJ
admet-2088	674	3	factor	factor	NOUN
admet-2088	675	1	i	i	PRON
admet-2088	675	2	...................................................	...................................................	PUNCT
admet-2088	676	1	nfi	nfi	PROPN
admet-2088	676	2	cytotoxic	cytotoxic	PROPN
admet-2088	676	3	t	t	PROPN
admet-2088	676	4	-	-	PUNCT
admet-2088	676	5	lymphocyte	lymphocyte	NOUN
admet-2088	676	6	–	–	PUNCT
admet-2088	676	7	associated	associated	ADJ
admet-2088	676	8	antigen	antigen	ADP
admet-2088	676	9	4	4	NUM
admet-2088	676	10	............................................................	............................................................	PUNCT
admet-2088	676	11	ctla-4	ctla-4	NUM
admet-2088	676	12	programmed	program	VERB
admet-2088	676	13	death	death	NOUN
admet-2088	676	14	1	1	NUM
admet-2088	676	15	.........................................	.........................................	PUNCT
admet-2088	676	16	pd-1	pd-1	VERB
admet-2088	676	17	photodynamic	photodynamic	ADJ
admet-2088	676	18	therapy	therapy	NOUN
admet-2088	676	19	......................................	......................................	PUNCT
admet-2088	677	1	pdt	pdt	PROPN
admet-2088	677	2	photothermal	photothermal	ADJ
admet-2088	677	3	therapy	therapy	NOUN
admet-2088	677	4	.......................................	.......................................	PUNCT
admet-2088	678	1	ptt	ptt	NOUN
admet-2088	678	2	nanoparticles	nanoparticle	NOUN
admet-2088	678	3	.....................................................	.....................................................	PUNCT
admet-2088	679	1	nps	nps	PROPN
admet-2088	679	2	nanomaterials	nanomaterial	NOUN
admet-2088	679	3	...................................................	...................................................	PUNCT
admet-2088	680	1	nms	nms	PROPN
admet-2088	680	2	solid	solid	ADJ
admet-2088	680	3	lipid	lipid	NOUN
admet-2088	680	4	nanoparticles	nanoparticle	NOUN
admet-2088	680	5	.....................................	.....................................	PUNCT
admet-2088	681	1	sln	sln	PROPN
admet-2088	681	2	monoclonal	monoclonal	NOUN
admet-2088	681	3	antibodies	antibody	NOUN
admet-2088	681	4	......................................	......................................	PUNCT
admet-2088	681	5	mab	mab	VERB
admet-2088	681	6	radial	radial	ADJ
admet-2088	681	7	growth	growth	NOUN
admet-2088	681	8	phase	phase	NOUN
admet-2088	681	9	..........................................	..........................................	PUNCT
admet-2088	682	1	rgp	rgp	PROPN
admet-2088	682	2	vertical	vertical	ADJ
admet-2088	682	3	growth	growth	NOUN
admet-2088	682	4	phase	phase	NOUN
admet-2088	682	5	........................................	........................................	PUNCT
admet-2088	683	1	vgp	vgp	PROPN
admet-2088	683	2	cyclin	cyclin	NOUN
admet-2088	683	3	-	-	PUNCT
admet-2088	683	4	dependent	dependent	ADJ
admet-2088	683	5	kinase	kinase	NOUN
admet-2088	683	6	inhibitor	inhibitor	PROPN
admet-2088	683	7	2a	2a	NUM
admet-2088	683	8	................	................	PUNCT
admet-2088	684	1	cdkn2a	cdkn2a	PROPN
admet-2088	684	2	mitogen	mitogen	NOUN
admet-2088	684	3	-	-	PUNCT
admet-2088	684	4	activated	activate	VERB
admet-2088	684	5	protein	protein	NOUN
admet-2088	684	6	kinase	kinase	NOUN
admet-2088	684	7	......................	......................	PUNCT
admet-2088	685	1	mapk	mapk	PROPN
admet-2088	685	2	admet	admet	PROPN
admet-2088	685	3	&	&	CCONJ
admet-2088	685	4	dmpk	dmpk	PROPN
admet-2088	685	5	12(1	12(1	PROPN
admet-2088	685	6	)	)	PUNCT
admet-2088	685	7	(	(	PUNCT
admet-2088	685	8	2024	2024	NUM
admet-2088	685	9	)	)	PUNCT
admet-2088	685	10	107	107	NUM
admet-2088	685	11	-	-	SYM
admet-2088	685	12	150	150	NUM
admet-2088	685	13	nanomaterial	nanomaterial	NOUN
admet-2088	685	14	-	-	PUNCT
admet-2088	685	15	based	base	VERB
admet-2088	685	16	drug	drug	NOUN
admet-2088	685	17	delivery	delivery	NOUN
admet-2088	685	18	systems	system	NOUN
admet-2088	685	19	for	for	ADP
admet-2088	685	20	melanoma	melanoma	NOUN
admet-2088	685	21	therapy	therapy	NOUN
admet-2088	685	22	doi	doi	NOUN
admet-2088	685	23	:	:	PUNCT
admet-2088	685	24	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	685	25	135	135	NUM
admet-2088	685	26	phosphatidylinositol	phosphatidylinositol	NOUN
admet-2088	685	27	3	3	NUM
admet-2088	685	28	-	-	PUNCT
admet-2088	685	29	kinase	kinase	NOUN
admet-2088	685	30	............................	............................	PUNCT
admet-2088	685	31	p13k	p13k	NOUN
admet-2088	685	32	/	/	SYM
admet-2088	685	33	akt	akt	PROPN
admet-2088	685	34	tyrosine	tyrosine	PROPN
admet-2088	685	35	kinase	kinase	PROPN
admet-2088	685	36	receptor	receptor	NOUN
admet-2088	685	37	...................................	...................................	PUNCT
admet-2088	686	1	c	c	X
admet-2088	686	2	-	-	PUNCT
admet-2088	686	3	kit	kit	NOUN
admet-2088	686	4	tumour	tumour	NOUN
admet-2088	686	5	infiltration	infiltration	NOUN
admet-2088	686	6	lymphocytes	lymphocyte	VERB
admet-2088	686	7	.......................	.......................	PUNCT
admet-2088	686	8	tils	til	NOUN
admet-2088	686	9	programmed	program	VERB
admet-2088	686	10	death	death	NOUN
admet-2088	686	11	ligand-1	ligand-1	NUM
admet-2088	686	12	..............................	..............................	PUNCT
admet-2088	687	1	pd	pd	PROPN
admet-2088	687	2	-	-	PROPN
admet-2088	687	3	l1	l1	PROPN
admet-2088	687	4	regulatory	regulatory	PROPN
admet-2088	687	5	t	t	PROPN
admet-2088	687	6	cells	cell	NOUN
admet-2088	687	7	...............................................	...............................................	PUNCT
admet-2088	687	8	tregs	treg	VERB
admet-2088	687	9	myeloid	myeloid	ADJ
admet-2088	687	10	-	-	PUNCT
admet-2088	687	11	derived	derive	VERB
admet-2088	687	12	suppressor	suppressor	NOUN
admet-2088	687	13	cells	cell	NOUN
admet-2088	687	14	......................	......................	PUNCT
admet-2088	688	1	mdscs	mdsc	NOUN
admet-2088	688	2	reactive	reactive	ADJ
admet-2088	688	3	oxygen	oxygen	NOUN
admet-2088	688	4	species	specie	NOUN
admet-2088	688	5	....................................	....................................	PUNCT
admet-2088	689	1	ros	ros	PROPN
admet-2088	689	2	light	light	ADV
admet-2088	689	3	-	-	PUNCT
admet-2088	689	4	emitting	emit	VERB
admet-2088	689	5	diodes	diode	NOUN
admet-2088	689	6	.........................................	.........................................	PUNCT
admet-2088	689	7	leds	led	VERB
admet-2088	689	8	polyethylene	polyethylene	NOUN
admet-2088	689	9	glycol	glycol	NOUN
admet-2088	689	10	conjugation	conjugation	NOUN
admet-2088	689	11	........................	........................	PUNCT
admet-2088	690	1	pegylation	pegylation	NOUN
admet-2088	690	2	enhanced	enhance	VERB
admet-2088	690	3	permeability	permeability	NOUN
admet-2088	690	4	and	and	CCONJ
admet-2088	690	5	retention	retention	NOUN
admet-2088	690	6	...............	...............	PUNCT
admet-2088	691	1	epr	epr	ADJ
admet-2088	691	2	mammalian	mammalian	ADJ
admet-2088	691	3	target	target	NOUN
admet-2088	691	4	of	of	ADP
admet-2088	691	5	rapamycin	rapamycin	PROPN
admet-2088	691	6	.......................	.......................	PUNCT
admet-2088	692	1	mtor	mtor	PROPN
admet-2088	692	2	sonodynamic	sonodynamic	ADJ
admet-2088	692	3	therapy	therapy	NOUN
admet-2088	692	4	........................................	........................................	PUNCT
admet-2088	693	1	sdt	sdt	PROPN
admet-2088	693	2	hyaluronic	hyaluronic	PROPN
admet-2088	693	3	acid	acid	NOUN
admet-2088	693	4	..................................................	..................................................	PUNCT
admet-2088	694	1	ha	ha	INTJ
admet-2088	694	2	4	4	NUM
admet-2088	694	3	-	-	PUNCT
admet-2088	694	4	mercapto	mercapto	NOUN
admet-2088	694	5	benzoic	benzoic	NOUN
admet-2088	694	6	acid	acid	NOUN
admet-2088	694	7	....................................	....................................	PUNCT
admet-2088	695	1	p	p	X
admet-2088	695	2	-	-	PUNCT
admet-2088	695	3	mba	mba	NOUN
admet-2088	695	4	carboxymethyl	carboxymethyl	NOUN
admet-2088	695	5	cellulose	cellulose	NOUN
admet-2088	695	6	....................................	....................................	PUNCT
admet-2088	696	1	cmc	cmc	PROPN
admet-2088	696	2	octadecylamine	octadecylamine	PROPN
admet-2088	696	3	.................................................	.................................................	PUNCT
admet-2088	696	4	oda	oda	PROPN
admet-2088	696	5	chemodynamic	chemodynamic	PROPN
admet-2088	696	6	therapy	therapy	PROPN
admet-2088	696	7	.....................................	.....................................	PUNCT
admet-2088	697	1	cdt	cdt	PROPN
admet-2088	697	2	cuprous	cuprous	ADJ
admet-2088	697	3	oxide	oxide	NOUN
admet-2088	697	4	nps	nps	PROPN
admet-2088	697	5	.............................................	.............................................	PUNCT
admet-2088	698	1	cu2o	cu2o	PROPN
admet-2088	698	2	-	-	PUNCT
admet-2088	698	3	nps	nps	PROPN
admet-2088	698	4	copper	copper	NOUN
admet-2088	698	5	telluride	telluride	NOUN
admet-2088	698	6	nps	nps	PROPN
admet-2088	698	7	..........................................	..........................................	PUNCT
admet-2088	699	1	ctnps	ctnps	PROPN
admet-2088	699	2	ovalbumin	ovalbumin	PROPN
admet-2088	699	3	..........................................................	..........................................................	PUNCT
admet-2088	699	4	ova	ova	VERB
admet-2088	699	5	upconversion	upconversion	NOUN
admet-2088	699	6	fluorescent	fluorescent	NOUN
admet-2088	699	7	nps	nps	PROPN
admet-2088	699	8	...........................	...........................	PUNCT
admet-2088	700	1	ucns	ucns	PROPN
admet-2088	700	2	mobil	mobil	NOUN
admet-2088	700	3	composition	composition	NOUN
admet-2088	700	4	of	of	ADP
admet-2088	700	5	matter	matter	NOUN
admet-2088	700	6	no	no	DET
admet-2088	700	7	41	41	NUM
admet-2088	700	8	...................	...................	PUNCT
admet-2088	701	1	mcm-41	mcm-41	PRON
admet-2088	701	2	metal	metal	NOUN
admet-2088	701	3	-	-	PUNCT
admet-2088	701	4	polyphenol	polyphenol	NOUN
admet-2088	701	5	network	network	NOUN
admet-2088	701	6	................................	................................	PUNCT
admet-2088	701	7	mpn	mpn	PROPN
admet-2088	701	8	chlorin	chlorin	NOUN
admet-2088	701	9	e6	e6	PROPN
admet-2088	701	10	...........................................................	...........................................................	PUNCT
admet-2088	701	11	ce6	ce6	VERB
admet-2088	701	12	alginate	alginate	NOUN
admet-2088	701	13	-	-	PUNCT
admet-2088	701	14	graft	graft	NOUN
admet-2088	701	15	-	-	PUNCT
admet-2088	701	16	dopamine	dopamine	NOUN
admet-2088	701	17	...................................	...................................	PUNCT
admet-2088	701	18	sd	sd	ADP
admet-2088	701	19	polydopamine	polydopamine	NOUN
admet-2088	701	20	-	-	PUNCT
admet-2088	701	21	fe(iii)-doxorubicin	fe(iii)-doxorubicin	ADJ
admet-2088	702	1	nps	nps	PROPN
admet-2088	702	2	..............	..............	PROPN
admet-2088	703	1	pfd	pfd	PROPN
admet-2088	703	2	carbon	carbon	NOUN
admet-2088	703	3	nanotubes	nanotube	NOUN
admet-2088	703	4	.............................................	.............................................	PUNCT
admet-2088	704	1	cnts	cnts	PROPN
admet-2088	704	2	single	single	ADJ
admet-2088	704	3	-	-	PUNCT
admet-2088	704	4	walled	wall	VERB
admet-2088	704	5	cnts	cnt	NOUN
admet-2088	704	6	.............................................	.............................................	PUNCT
admet-2088	705	1	swcnts	swcnt	VERB
admet-2088	705	2	multi	multi	ADJ
admet-2088	705	3	-	-	ADJ
admet-2088	705	4	walled	walled	ADJ
admet-2088	705	5	cnts	cnt	NOUN
admet-2088	705	6	..............................................	..............................................	PUNCT
admet-2088	706	1	mwcnts	mwcnt	NOUN
admet-2088	706	2	polypyrrole	polypyrrole	NOUN
admet-2088	706	3	.........................................................	.........................................................	PUNCT
admet-2088	707	1	pp	pp	ADV
admet-2088	707	2	graphene	graphene	VERB
admet-2088	707	3	oxide	oxide	NOUN
admet-2088	707	4	.................................................	.................................................	PUNCT
admet-2088	707	5	go	go	VERB
admet-2088	707	6	reduced	reduce	VERB
admet-2088	707	7	go	go	VERB
admet-2088	707	8	......................................................	......................................................	PUNCT
admet-2088	708	1	rgo	rgo	PROPN
admet-2088	708	2	carboxymethylarabinoxylan	carboxymethylarabinoxylan	PROPN
admet-2088	708	3	...............................	...............................	PUNCT
admet-2088	708	4	cmarx	cmarx	PROPN
admet-2088	708	5	plasmid	plasmid	ADJ
admet-2088	708	6	dna	dna	PROPN
admet-2088	708	7	......................................................	......................................................	PUNCT
admet-2088	708	8	pdna	pdna	PROPN
admet-2088	708	9	graphene	graphene	NOUN
admet-2088	708	10	-	-	PUNCT
admet-2088	708	11	encapsulated	encapsulate	VERB
admet-2088	708	12	magnetic	magnetic	PROPN
admet-2088	708	13	nps	nps	PROPN
admet-2088	708	14	..............	..............	PROPN
admet-2088	708	15	gemns	gemns	PROPN
admet-2088	708	16	polyethyleneimine	polyethyleneimine	PROPN
admet-2088	708	17	.............................................	.............................................	PUNCT
admet-2088	709	1	pei	pei	PROPN
admet-2088	709	2	factor	factor	PROPN
admet-2088	709	3	β	β	X
admet-2088	709	4	signalling	signal	VERB
admet-2088	709	5	pathway	pathway	NOUN
admet-2088	709	6	...............................	...............................	PUNCT
admet-2088	710	1	tgf	tgf	PROPN
admet-2088	710	2	-	-	PUNCT
admet-2088	710	3	β	β	PROPN
admet-2088	710	4	poly(lactic	poly(lactic	ADJ
admet-2088	710	5	acid	acid	NOUN
admet-2088	710	6	)	)	PUNCT
admet-2088	710	7	..................................................	..................................................	PUNCT
admet-2088	711	1	pla	pla	PROPN
admet-2088	711	2	poly	poly	ADJ
admet-2088	711	3	(	(	PUNCT
admet-2088	711	4	glycolic	glycolic	NOUN
admet-2088	711	5	acid	acid	NOUN
admet-2088	711	6	)	)	PUNCT
admet-2088	711	7	..............................................	..............................................	PUNCT
admet-2088	712	1	pga	pga	PROPN
admet-2088	712	2	poly(lactic	poly(lactic	NOUN
admet-2088	712	3	-	-	PUNCT
admet-2088	712	4	co	co	NOUN
admet-2088	712	5	-	-	ADJ
admet-2088	712	6	glycolic	glycolic	ADJ
admet-2088	712	7	acid	acid	NOUN
admet-2088	712	8	)	)	PUNCT
admet-2088	712	9	................................	................................	PUNCT
admet-2088	713	1	plga	plga	VERB
admet-2088	713	2	poly(-caprolactone	poly(-caprolactone	PROPN
admet-2088	713	3	)	)	PUNCT
admet-2088	713	4	..........................................	..........................................	PUNCT
admet-2088	714	1	pcl	pcl	PROPN
admet-2088	714	2	phenylboronic	phenylboronic	ADJ
admet-2088	714	3	acid	acid	NOUN
admet-2088	714	4	............................................	............................................	PUNCT
admet-2088	715	1	pba	pba	PROPN
admet-2088	715	2	2	2	NUM
admet-2088	715	3	-	-	PUNCT
admet-2088	715	4	aminoethylmethacrylate	aminoethylmethacrylate	NOUN
admet-2088	715	5	................................	................................	PUNCT
admet-2088	715	6	aema	aema	PROPN
admet-2088	715	7	polyamide	polyamide	NOUN
admet-2088	715	8	amine	amine	ADJ
admet-2088	715	9	dendrimer	dendrimer	NOUN
admet-2088	715	10	.............................	.............................	PUNCT
admet-2088	715	11	pamam	pamam	NOUN
admet-2088	715	12	glucose	glucose	NOUN
admet-2088	715	13	oxidase	oxidase	NOUN
admet-2088	715	14	.................................................	.................................................	PUNCT
admet-2088	716	1	gox	gox	PROPN
admet-2088	716	2	4	4	NUM
admet-2088	716	3	-	-	PUNCT
admet-2088	716	4	formyl	formyl	NOUN
admet-2088	716	5	-	-	PUNCT
admet-2088	716	6	n-(3-(2-(2-(3	n-(3-(2-(2-(3	NOUN
admet-2088	716	7	-	-	ADJ
admet-2088	716	8	methacrylamidopro	methacrylamidopro	ADJ
admet-2088	716	9	poxy)ethoxy)-ethoxy)propyl	poxy)ethoxy)-ethoxy)propyl	NOUN
admet-2088	716	10	)	)	PUNCT
admet-2088	716	11	benzamide	benzamide	NOUN
admet-2088	716	12	..........	..........	PUNCT
admet-2088	717	1	fbma	fbma	ADJ
admet-2088	717	2	oligo	oligo	ADJ
admet-2088	717	3	ethylene	ethylene	NOUN
admet-2088	717	4	glycolmonomethyl	glycolmonomethyl	ADJ
admet-2088	717	5	ether	ether	PROPN
admet-2088	717	6	methacrylate	methacrylate	NOUN
admet-2088	717	7	............................................	............................................	PUNCT
admet-2088	717	8	oegma	oegma	ADJ
admet-2088	717	9	phosphatidylcholine	phosphatidylcholine	NOUN
admet-2088	717	10	..........................................	..........................................	PUNCT
admet-2088	717	11	pc	pc	NOUN
admet-2088	717	12	phosphatidylethanolamine	phosphatidylethanolamine	NOUN
admet-2088	717	13	................................	................................	PUNCT
admet-2088	718	1	pe	pe	PROPN
admet-2088	718	2	4	4	NUM
admet-2088	718	3	-	-	NUM
admet-2088	718	4	nitrochalcone	nitrochalcone	NOUN
admet-2088	718	5	..................................................	..................................................	PUNCT
admet-2088	718	6	4nc	4nc	ADJ
admet-2088	718	7	sodium	sodium	PROPN
admet-2088	718	8	diethyldithiocarbamate	diethyldithiocarbamate	NOUN
admet-2088	718	9	........................	........................	PUNCT
admet-2088	719	1	detc	detc	NOUN
admet-2088	719	2	blood	blood	NOUN
admet-2088	719	3	-	-	PUNCT
admet-2088	719	4	brain	brain	NOUN
admet-2088	719	5	-	-	PUNCT
admet-2088	719	6	barrier	barrier	NOUN
admet-2088	719	7	............................................	............................................	PUNCT
admet-2088	719	8	bbb	bbb	PROPN
admet-2088	719	9	red	red	ADJ
admet-2088	719	10	blood	blood	NOUN
admet-2088	719	11	cell	cell	NOUN
admet-2088	719	12	....................................................	....................................................	PUNCT
admet-2088	720	1	rbc	rbc	PROPN
admet-2088	720	2	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	PROPN
admet-2088	720	3	m.	m.	NOUN
admet-2088	720	4	kulkarni	kulkarni	PROPN
admet-2088	720	5	et	et	PROPN
admet-2088	720	6	al	al	PROPN
admet-2088	720	7	.	.	PROPN
admet-2088	720	8	admet	admet	PROPN
admet-2088	720	9	&	&	CCONJ
admet-2088	720	10	dmpk	dmpk	PROPN
admet-2088	720	11	12(1	12(1	PROPN
admet-2088	720	12	)	)	PUNCT
admet-2088	720	13	(	(	PUNCT
admet-2088	720	14	2024	2024	NUM
admet-2088	720	15	)	)	PUNCT
admet-2088	720	16	107	107	NUM
admet-2088	720	17	-	-	SYM
admet-2088	720	18	150	150	NUM
admet-2088	720	19	136	136	NUM
admet-2088	720	20	conflict	conflict	NOUN
admet-2088	720	21	of	of	ADP
admet-2088	720	22	interest	interest	NOUN
admet-2088	720	23	:	:	PUNCT
admet-2088	720	24	the	the	DET
admet-2088	720	25	authors	author	NOUN
admet-2088	720	26	claim	claim	VERB
admet-2088	720	27	no	no	DET
admet-2088	720	28	conflict	conflict	NOUN
admet-2088	720	29	of	of	ADP
admet-2088	720	30	interest	interest	NOUN
admet-2088	720	31	.	.	PUNCT
admet-2088	721	1	references	reference	NOUN
admet-2088	721	2	[	[	X
admet-2088	721	3	1	1	NUM
admet-2088	721	4	]	]	PUNCT
admet-2088	721	5	k.	k.	PROPN
admet-2088	721	6	bromma	bromma	PROPN
admet-2088	721	7	,	,	PUNCT
admet-2088	721	8	l.	l.	PROPN
admet-2088	721	9	cicon	cicon	PROPN
admet-2088	721	10	,	,	PUNCT
admet-2088	721	11	w.	w.	PROPN
admet-2088	721	12	beckham	beckham	PROPN
admet-2088	721	13	,	,	PUNCT
admet-2088	721	14	d.b	d.b	PROPN
admet-2088	721	15	.	.	PROPN
admet-2088	721	16	chithrani	chithrani	PROPN
admet-2088	721	17	.	.	PUNCT
admet-2088	722	1	gold	gold	NOUN
admet-2088	722	2	nanoparticle	nanoparticle	NOUN
admet-2088	722	3	mediated	mediate	VERB
admet-2088	722	4	radiation	radiation	NOUN
admet-2088	722	5	response	response	NOUN
admet-2088	722	6	among	among	ADP
admet-2088	722	7	key	key	ADJ
admet-2088	722	8	cell	cell	NOUN
admet-2088	722	9	components	component	NOUN
admet-2088	722	10	of	of	ADP
admet-2088	722	11	the	the	DET
admet-2088	722	12	tumour	tumour	NOUN
admet-2088	722	13	microenvironment	microenvironment	NOUN
admet-2088	722	14	for	for	ADP
admet-2088	722	15	the	the	DET
admet-2088	722	16	advancement	advancement	NOUN
admet-2088	722	17	of	of	ADP
admet-2088	722	18	cancer	cancer	NOUN
admet-2088	722	19	nanotechnology	nanotechnology	PROPN
admet-2088	722	20	.	.	PUNCT
admet-2088	723	1	scientific	scientific	ADJ
admet-2088	723	2	reports	report	NOUN
admet-2088	723	3	10	10	NUM
admet-2088	723	4	(	(	PUNCT
admet-2088	723	5	2020	2020	NUM
admet-2088	723	6	)	)	PUNCT
admet-2088	723	7	12096	12096	NUM
admet-2088	723	8	.	.	PUNCT
admet-2088	724	1	https://www.nature.com/articles/s41598-02068994-0	https://www.nature.com/articles/s41598-02068994-0	VERB
admet-2088	724	2	.	.	PUNCT
admet-2088	725	1	[	[	X
admet-2088	725	2	2	2	X
admet-2088	725	3	]	]	X
admet-2088	725	4	a.l	a.l	PROPN
admet-2088	725	5	.	.	PROPN
admet-2088	725	6	ruiz	ruiz	PROPN
admet-2088	725	7	,	,	PUNCT
admet-2088	725	8	c.b	c.b	PROPN
admet-2088	725	9	.	.	PROPN
admet-2088	725	10	garcia	garcia	PROPN
admet-2088	725	11	,	,	PUNCT
admet-2088	725	12	s.n	s.n	PROPN
admet-2088	725	13	.	.	PROPN
admet-2088	725	14	gallón	gallón	PROPN
admet-2088	725	15	,	,	PUNCT
admet-2088	725	16	t.j	t.j	PROPN
admet-2088	725	17	.	.	PROPN
admet-2088	725	18	webster	webster	PROPN
admet-2088	725	19	.	.	PUNCT
admet-2088	726	1	novel	novel	ADJ
admet-2088	726	2	silver	silver	ADJ
admet-2088	726	3	-	-	PUNCT
admet-2088	726	4	platinum	platinum	NOUN
admet-2088	726	5	nanoparticles	nanoparticle	NOUN
admet-2088	726	6	for	for	ADP
admet-2088	726	7	anticancer	anticancer	NOUN
admet-2088	726	8	and	and	CCONJ
admet-2088	726	9	antimicrobial	antimicrobial	ADJ
admet-2088	726	10	applications	application	NOUN
admet-2088	726	11	.	.	PUNCT
admet-2088	727	1	international	international	ADJ
admet-2088	727	2	journal	journal	PROPN
admet-2088	727	3	of	of	ADP
admet-2088	727	4	nanomedicine	nanomedicine	NOUN
admet-2088	727	5	15	15	NUM
admet-2088	727	6	(	(	PUNCT
admet-2088	727	7	2020	2020	NUM
admet-2088	727	8	)	)	PUNCT
admet-2088	727	9	169	169	NUM
admet-2088	727	10	-	-	SYM
admet-2088	727	11	179	179	NUM
admet-2088	727	12	.	.	PUNCT
admet-2088	728	1	https://doi.org/10.2147/ijn.s176737	https://doi.org/10.2147/ijn.s176737	NOUN
admet-2088	728	2	.	.	PUNCT
admet-2088	729	1	[	[	X
admet-2088	729	2	3	3	NUM
admet-2088	729	3	]	]	X
admet-2088	729	4	x.y	x.y	PROPN
admet-2088	729	5	.	.	PROPN
admet-2088	729	6	wong	wong	PROPN
admet-2088	729	7	,	,	PUNCT
admet-2088	729	8	a.	a.	PROPN
admet-2088	729	9	sena	sena	PROPN
admet-2088	729	10	-	-	PUNCT
admet-2088	729	11	torralba	torralba	PROPN
admet-2088	729	12	,	,	PUNCT
admet-2088	729	13	r.	r.	PROPN
admet-2088	729	14	álvarez	álvarez	PROPN
admet-2088	729	15	-	-	PUNCT
admet-2088	729	16	diduk	diduk	PROPN
admet-2088	729	17	,	,	PUNCT
admet-2088	729	18	k.	k.	PROPN
admet-2088	729	19	muthoosamy	muthoosamy	PROPN
admet-2088	729	20	,	,	PUNCT
admet-2088	729	21	a.	a.	NOUN
admet-2088	729	22	merkoc	merkoc	PROPN
admet-2088	729	23	.	.	PUNCT
admet-2088	730	1	nanomaterials	nanomaterial	NOUN
admet-2088	730	2	for	for	ADP
admet-2088	730	3	nanotheranostics	nanotheranostic	NOUN
admet-2088	730	4	:	:	PUNCT
admet-2088	730	5	their	their	PRON
admet-2088	730	6	properties	property	NOUN
admet-2088	730	7	according	accord	VERB
admet-2088	730	8	to	to	ADP
admet-2088	730	9	disease	disease	NOUN
admet-2088	730	10	needs	need	NOUN
admet-2088	730	11	.	.	PUNCT
admet-2088	731	1	acs	acs	PROPN
admet-2088	731	2	nano	nano	VERB
admet-2088	731	3	14	14	NUM
admet-2088	731	4	(	(	PUNCT
admet-2088	731	5	2020	2020	NUM
admet-2088	731	6	)	)	PUNCT
admet-2088	731	7	2585	2585	NUM
admet-2088	731	8	-	-	SYM
admet-2088	731	9	2627	2627	NUM
admet-2088	731	10	.	.	PUNCT
admet-2088	732	1	https://doi.org/10.1021/acsnano.9b08133	https://doi.org/10.1021/acsnano.9b08133	NOUN
admet-2088	732	2	.	.	PUNCT
admet-2088	733	1	[	[	X
admet-2088	733	2	4	4	NUM
admet-2088	733	3	]	]	X
admet-2088	733	4	p.n	p.n	PROPN
admet-2088	733	5	.	.	PROPN
admet-2088	733	6	navya	navya	PROPN
admet-2088	733	7	,	,	PUNCT
admet-2088	733	8	a.	a.	PROPN
admet-2088	733	9	kaphle	kaphle	PROPN
admet-2088	733	10	,	,	PUNCT
admet-2088	733	11	s.p	s.p	PROPN
admet-2088	733	12	.	.	PROPN
admet-2088	733	13	srinivas	srinivas	PROPN
admet-2088	733	14	,	,	PUNCT
admet-2088	733	15	s.k	s.k	PROPN
admet-2088	733	16	.	.	PROPN
admet-2088	733	17	bhargava	bhargava	PROPN
admet-2088	733	18	,	,	PUNCT
admet-2088	733	19	v.m	v.m	PROPN
admet-2088	733	20	.	.	PROPN
admet-2088	733	21	rotello	rotello	PROPN
admet-2088	733	22	,	,	PUNCT
admet-2088	733	23	h.k	h.k	PROPN
admet-2088	733	24	.	.	PROPN
admet-2088	733	25	daima	daima	PROPN
admet-2088	733	26	.	.	PUNCT
admet-2088	734	1	current	current	ADJ
admet-2088	734	2	trends	trend	NOUN
admet-2088	734	3	and	and	CCONJ
admet-2088	734	4	challenges	challenge	NOUN
admet-2088	734	5	in	in	ADP
admet-2088	734	6	cancer	cancer	NOUN
admet-2088	734	7	management	management	NOUN
admet-2088	734	8	and	and	CCONJ
admet-2088	734	9	therapy	therapy	NOUN
admet-2088	734	10	using	use	VERB
admet-2088	734	11	designer	designer	NOUN
admet-2088	734	12	nanomaterials	nanomaterial	NOUN
admet-2088	734	13	.	.	PUNCT
admet-2088	735	1	nano	nano	NOUN
admet-2088	735	2	convergence	convergence	NOUN
admet-2088	735	3	6	6	NUM
admet-2088	735	4	(	(	PUNCT
admet-2088	735	5	2019	2019	NUM
admet-2088	735	6	)	)	PUNCT
admet-2088	735	7	23	23	NUM
admet-2088	735	8	.	.	PUNCT
admet-2088	735	9	https://doi.org/10.1186/s40580-019-0193-2	https://doi.org/10.1186/s40580-019-0193-2	PROPN
admet-2088	735	10	.	.	PUNCT
admet-2088	736	1	[	[	X
admet-2088	736	2	5	5	NUM
admet-2088	736	3	]	]	X
admet-2088	736	4	c.g.a	c.g.a	NOUN
admet-2088	736	5	.	.	PUNCT
admet-2088	737	1	das	das	PROPN
admet-2088	737	2	,	,	PUNCT
admet-2088	737	3	v.	v.	PROPN
admet-2088	737	4	kumar	kumar	PROPN
admet-2088	737	5	,	,	PUNCT
admet-2088	737	6	t.s	t.s	PROPN
admet-2088	737	7	.	.	PROPN
admet-2088	737	8	dhas	dhas	PROPN
admet-2088	737	9	,	,	PUNCT
admet-2088	737	10	v.	v.	PROPN
admet-2088	737	11	karthick	karthick	PROPN
admet-2088	737	12	,	,	PUNCT
admet-2088	737	13	c.m.v	c.m.v	PROPN
admet-2088	737	14	.	.	PUNCT
admet-2088	738	1	kumar	kumar	PROPN
admet-2088	738	2	.	.	PUNCT
admet-2088	738	3	nanomaterials	nanomaterial	NOUN
admet-2088	738	4	in	in	ADP
admet-2088	738	5	anticancer	anticancer	NOUN
admet-2088	738	6	applications	application	NOUN
admet-2088	738	7	and	and	CCONJ
admet-2088	738	8	their	their	PRON
admet-2088	738	9	mechanism	mechanism	NOUN
admet-2088	738	10	of	of	ADP
admet-2088	738	11	actiona	actiona	PROPN
admet-2088	738	12	review	review	PROPN
admet-2088	738	13	.	.	PUNCT
admet-2088	739	1	nanomedicine	nanomedicine	PROPN
admet-2088	739	2	:	:	PUNCT
admet-2088	739	3	nanotechnology	nanotechnology	NOUN
admet-2088	739	4	,	,	PUNCT
admet-2088	739	5	biology	biology	NOUN
admet-2088	739	6	,	,	PUNCT
admet-2088	739	7	and	and	CCONJ
admet-2088	739	8	medicine	medicine	NOUN
admet-2088	739	9	47	47	NUM
admet-2088	739	10	(	(	PUNCT
admet-2088	739	11	2023	2023	NUM
admet-2088	739	12	)	)	PUNCT
admet-2088	739	13	102613	102613	NUM
admet-2088	739	14	.	.	PUNCT
admet-2088	740	1	https://doi.org/10.1016/j.nano.2022.102613	https://doi.org/10.1016/j.nano.2022.102613	NOUN
admet-2088	740	2	.	.	PUNCT
admet-2088	741	1	[	[	X
admet-2088	741	2	6	6	NUM
admet-2088	741	3	]	]	PUNCT
admet-2088	741	4	m.	m.	NOUN
admet-2088	741	5	arnold	arnold	PROPN
admet-2088	741	6	,	,	PUNCT
admet-2088	741	7	d.	d.	PROPN
admet-2088	741	8	singh	singh	PROPN
admet-2088	741	9	,	,	PUNCT
admet-2088	741	10	m.	m.	NOUN
admet-2088	741	11	laversanne	laversanne	PROPN
admet-2088	741	12	,	,	PUNCT
admet-2088	741	13	j.	j.	PROPN
admet-2088	741	14	vignat	vignat	PROPN
admet-2088	741	15	,	,	PUNCT
admet-2088	741	16	s.	s.	PROPN
admet-2088	741	17	vaccarella	vaccarella	PROPN
admet-2088	741	18	,	,	PUNCT
admet-2088	741	19	f.	f.	PROPN
admet-2088	741	20	meheus	meheus	PROPN
admet-2088	741	21	,	,	PUNCT
admet-2088	741	22	a.e	a.e	PROPN
admet-2088	741	23	.	.	PROPN
admet-2088	741	24	cust	cust	PROPN
admet-2088	741	25	,	,	PUNCT
admet-2088	741	26	e.	e.	PROPN
admet-2088	741	27	de	de	PROPN
admet-2088	741	28	vries	vries	PROPN
admet-2088	741	29	,	,	PUNCT
admet-2088	741	30	d.c	d.c	PROPN
admet-2088	741	31	.	.	PROPN
admet-2088	741	32	whiteman	whiteman	PROPN
admet-2088	741	33	,	,	PUNCT
admet-2088	741	34	f.	f.	PROPN
admet-2088	741	35	bray	bray	PROPN
admet-2088	741	36	.	.	PUNCT
admet-2088	742	1	global	global	ADJ
admet-2088	742	2	burden	burden	NOUN
admet-2088	742	3	of	of	ADP
admet-2088	742	4	cutaneous	cutaneous	ADJ
admet-2088	742	5	melanoma	melanoma	NOUN
admet-2088	742	6	in	in	ADP
admet-2088	742	7	2020	2020	NUM
admet-2088	742	8	and	and	CCONJ
admet-2088	742	9	projections	projection	NOUN
admet-2088	742	10	to	to	ADP
admet-2088	742	11	2040	2040	NUM
admet-2088	742	12	.	.	PUNCT
admet-2088	743	1	jama	jama	PROPN
admet-2088	743	2	dermatology	dermatology	NOUN
admet-2088	743	3	158	158	NUM
admet-2088	743	4	(	(	PUNCT
admet-2088	743	5	2022	2022	NUM
admet-2088	743	6	)	)	PUNCT
admet-2088	743	7	495	495	NUM
admet-2088	743	8	-	-	SYM
admet-2088	743	9	503	503	NUM
admet-2088	743	10	.	.	PUNCT
admet-2088	744	1	https://doi.org/10.1001/jamadermatol.2022.0160	https://doi.org/10.1001/jamadermatol.2022.0160	PROPN
admet-2088	744	2	.	.	PUNCT
admet-2088	745	1	[	[	X
admet-2088	745	2	7	7	NUM
admet-2088	745	3	]	]	X
admet-2088	745	4	m.	m.	NOUN
admet-2088	745	5	russi	russi	PROPN
admet-2088	745	6	,	,	PUNCT
admet-2088	745	7	r.	r.	PROPN
admet-2088	745	8	valeri	valeri	PROPN
admet-2088	745	9	,	,	PUNCT
admet-2088	745	10	d.	d.	PROPN
admet-2088	745	11	marson	marson	PROPN
admet-2088	745	12	,	,	PUNCT
admet-2088	745	13	c.	c.	PROPN
admet-2088	745	14	danielli	danielli	PROPN
admet-2088	745	15	,	,	PUNCT
admet-2088	745	16	f.	f.	PROPN
admet-2088	745	17	felluga	felluga	PROPN
admet-2088	745	18	,	,	PUNCT
admet-2088	745	19	a.	a.	NOUN
admet-2088	745	20	tintaru	tintaru	NOUN
admet-2088	745	21	,	,	PUNCT
admet-2088	745	22	n.	n.	PROPN
admet-2088	745	23	skoko	skoko	PROPN
admet-2088	745	24	,	,	PUNCT
admet-2088	745	25	s.	s.	PROPN
admet-2088	745	26	aulic	aulic	PROPN
admet-2088	745	27	,	,	PUNCT
admet-2088	745	28	e.	e.	PROPN
admet-2088	745	29	laurini	laurini	PROPN
admet-2088	745	30	,	,	PUNCT
admet-2088	745	31	s.	s.	PROPN
admet-2088	745	32	pricl	pricl	PROPN
admet-2088	745	33	.	.	PUNCT
admet-2088	746	1	some	some	DET
admet-2088	746	2	things	thing	NOUN
admet-2088	746	3	old	old	ADJ
admet-2088	746	4	,	,	PUNCT
admet-2088	746	5	new	new	ADJ
admet-2088	746	6	and	and	CCONJ
admet-2088	746	7	borrowed	borrow	VERB
admet-2088	746	8	:	:	PUNCT
admet-2088	746	9	delivery	delivery	NOUN
admet-2088	746	10	of	of	ADP
admet-2088	746	11	dabrafenib	dabrafenib	NOUN
admet-2088	746	12	and	and	CCONJ
admet-2088	746	13	vemurafenib	vemurafenib	NOUN
admet-2088	746	14	to	to	ADP
admet-2088	746	15	melanoma	melanoma	NOUN
admet-2088	746	16	cells	cell	NOUN
admet-2088	746	17	via	via	ADP
admet-2088	746	18	self	self	NOUN
admet-2088	746	19	-	-	PUNCT
admet-2088	746	20	assembled	assemble	VERB
admet-2088	746	21	nanomicelles	nanomicelle	NOUN
admet-2088	746	22	based	base	VERB
admet-2088	746	23	on	on	ADP
admet-2088	746	24	an	an	DET
admet-2088	746	25	amphiphilic	amphiphilic	ADJ
admet-2088	746	26	dendrimer	dendrimer	NOUN
admet-2088	746	27	.	.	PUNCT
admet-2088	747	1	european	european	PROPN
admet-2088	747	2	journal	journal	PROPN
admet-2088	747	3	of	of	ADP
admet-2088	747	4	pharmaceutical	pharmaceutical	PROPN
admet-2088	747	5	sciences	science	NOUN
admet-2088	747	6	180	180	NUM
admet-2088	747	7	(	(	PUNCT
admet-2088	747	8	2023	2023	NUM
admet-2088	747	9	)	)	PUNCT
admet-2088	747	10	106311	106311	NUM
admet-2088	747	11	.	.	PUNCT
admet-2088	748	1	https://doi.org/10.1016/j.ejps.2022.106311	https://doi.org/10.1016/j.ejps.2022.106311	NOUN
admet-2088	748	2	.	.	PUNCT
admet-2088	749	1	[	[	X
admet-2088	749	2	8	8	NUM
admet-2088	749	3	]	]	X
admet-2088	749	4	f.	f.	PROPN
admet-2088	749	5	bray	bray	PROPN
admet-2088	749	6	,	,	PUNCT
admet-2088	749	7	j.	j.	PROPN
admet-2088	749	8	ferlay	ferlay	PROPN
admet-2088	749	9	,	,	PUNCT
admet-2088	749	10	i.	i.	PROPN
admet-2088	749	11	soerjomataram	soerjomataram	PROPN
admet-2088	749	12	,	,	PUNCT
admet-2088	749	13	r.l	r.l	PROPN
admet-2088	749	14	.	.	PROPN
admet-2088	749	15	siegel	siegel	PROPN
admet-2088	749	16	,	,	PUNCT
admet-2088	749	17	l.a	l.a	PROPN
admet-2088	749	18	.	.	PROPN
admet-2088	749	19	torre	torre	PROPN
admet-2088	749	20	,	,	PUNCT
admet-2088	749	21	a.	a.	PROPN
admet-2088	749	22	jemal	jemal	PROPN
admet-2088	749	23	.	.	PUNCT
admet-2088	750	1	global	global	ADJ
admet-2088	750	2	cancer	cancer	NOUN
admet-2088	750	3	statistics	statistic	NOUN
admet-2088	750	4	2018	2018	NUM
admet-2088	750	5	:	:	PUNCT
admet-2088	750	6	globocan	globocan	PROPN
admet-2088	750	7	estimates	estimate	NOUN
admet-2088	750	8	of	of	ADP
admet-2088	750	9	incidence	incidence	NOUN
admet-2088	750	10	and	and	CCONJ
admet-2088	750	11	mortality	mortality	NOUN
admet-2088	750	12	worldwide	worldwide	ADV
admet-2088	750	13	for	for	ADP
admet-2088	750	14	36	36	NUM
admet-2088	750	15	cancers	cancer	NOUN
admet-2088	750	16	in	in	ADP
admet-2088	750	17	185	185	NUM
admet-2088	750	18	countries	country	NOUN
admet-2088	750	19	.	.	PUNCT
admet-2088	751	1	ca	can	AUX
admet-2088	751	2	:	:	PUNCT
admet-2088	751	3	a	a	DET
admet-2088	751	4	cancer	cancer	NOUN
admet-2088	751	5	journal	journal	NOUN
admet-2088	751	6	for	for	ADP
admet-2088	751	7	clinicians	clinician	NOUN
admet-2088	751	8	68	68	NUM
admet-2088	751	9	(	(	PUNCT
admet-2088	751	10	2018	2018	NUM
admet-2088	751	11	)	)	PUNCT
admet-2088	751	12	394	394	NUM
admet-2088	751	13	-	-	SYM
admet-2088	751	14	424	424	NUM
admet-2088	751	15	.	.	PUNCT
admet-2088	752	1	https://doi.org/10.3322/caac.21492	https://doi.org/10.3322/caac.21492	NOUN
admet-2088	752	2	.	.	PUNCT
admet-2088	753	1	[	[	X
admet-2088	753	2	9	9	NUM
admet-2088	753	3	]	]	X
admet-2088	753	4	j.p	j.p	PROPN
admet-2088	753	5	.	.	PROPN
admet-2088	753	6	gonçalves	gonçalves	PROPN
admet-2088	753	7	,	,	PUNCT
admet-2088	753	8	a.f	a.f	PROPN
admet-2088	753	9	.	.	PUNCT
admet-2088	753	10	da	da	PROPN
admet-2088	753	11	cruz	cruz	PROPN
admet-2088	753	12	,	,	PUNCT
admet-2088	753	13	a.m.	a.m.	PROPN
admet-2088	753	14	nunes	nunes	PROPN
admet-2088	753	15	,	,	PUNCT
admet-2088	753	16	m.r	m.r	PROPN
admet-2088	753	17	.	.	PROPN
admet-2088	753	18	meneghetti	meneghetti	PROPN
admet-2088	753	19	,	,	PUNCT
admet-2088	753	20	h.r	h.r	PROPN
admet-2088	753	21	.	.	PROPN
admet-2088	753	22	de	de	PROPN
admet-2088	753	23	barros	barros	PROPN
admet-2088	753	24	,	,	PUNCT
admet-2088	753	25	b.s	b.s	PROPN
admet-2088	753	26	.	.	PROPN
admet-2088	753	27	borges	borges	PROPN
admet-2088	753	28	,	,	PUNCT
admet-2088	753	29	l.c.a.s	l.c.a.s	PROPN
admet-2088	753	30	.	.	PROPN
admet-2088	753	31	de	de	PROPN
admet-2088	753	32	medeiros	medeiros	PROPN
admet-2088	753	33	,	,	PUNCT
admet-2088	753	34	m.j	m.j	PROPN
admet-2088	753	35	.	.	PROPN
admet-2088	753	36	soares	soares	PROPN
admet-2088	753	37	,	,	PUNCT
admet-2088	753	38	m.p	m.p	PROPN
admet-2088	753	39	.	.	PROPN
admet-2088	753	40	dos	dos	PROPN
admet-2088	753	41	santos	santos	PROPN
admet-2088	753	42	,	,	PUNCT
admet-2088	753	43	m.t	m.t	PROPN
admet-2088	753	44	.	.	PROPN
admet-2088	753	45	grassi	grassi	PROPN
admet-2088	753	46	,	,	PUNCT
admet-2088	753	47	g.r	g.r	PROPN
admet-2088	753	48	.	.	PROPN
admet-2088	753	49	rossi	rossi	PROPN
admet-2088	753	50	,	,	PUNCT
admet-2088	753	51	d.l	d.l	PROPN
admet-2088	753	52	.	.	PROPN
admet-2088	753	53	bellan	bellan	PROPN
admet-2088	753	54	,	,	PUNCT
admet-2088	753	55	s.m.p	s.m.p	PROPN
admet-2088	753	56	.	.	PROPN
admet-2088	753	57	biscaia	biscaia	PROPN
admet-2088	753	58	,	,	PUNCT
admet-2088	753	59	a.m.	a.m.	PROPN
admet-2088	753	60	cristal	cristal	PROPN
admet-2088	753	61	,	,	PUNCT
admet-2088	753	62	j.l.a	j.l.a	PROPN
admet-2088	753	63	.	.	PROPN
admet-2088	753	64	buzzo	buzzo	PROPN
admet-2088	753	65	,	,	PUNCT
admet-2088	753	66	y.c	y.c	PROPN
admet-2088	753	67	.	.	PROPN
admet-2088	753	68	ribeiro	ribeiro	PROPN
admet-2088	753	69	,	,	PUNCT
admet-2088	753	70	a.	a.	PROPN
admet-2088	753	71	acco	acco	PROPN
admet-2088	753	72	,	,	PUNCT
admet-2088	753	73	m.b	m.b	PROPN
admet-2088	753	74	.	.	PROPN
admet-2088	753	75	cardoso	cardoso	PROPN
admet-2088	753	76	,	,	PUNCT
admet-2088	753	77	f.f	f.f	PROPN
admet-2088	753	78	.	.	PROPN
admet-2088	753	79	simas	simas	PROPN
admet-2088	753	80	,	,	PUNCT
admet-2088	753	81	e.s	e.s	PROPN
admet-2088	753	82	.	.	PROPN
admet-2088	753	83	trindade	trindade	PROPN
admet-2088	753	84	,	,	PUNCT
admet-2088	753	85	i.c	i.c	PROPN
admet-2088	753	86	.	.	PROPN
admet-2088	753	87	riegel	riegel	PROPN
admet-2088	753	88	-	-	PUNCT
admet-2088	753	89	vidotti	vidotti	PROPN
admet-2088	753	90	,	,	PUNCT
admet-2088	753	91	c.c	c.c	PROPN
admet-2088	753	92	.	.	PROPN
admet-2088	753	93	de	de	PROPN
admet-2088	753	94	oliveira	oliveira	PROPN
admet-2088	753	95	.	.	PUNCT
admet-2088	753	96	biocompatible	biocompatible	ADJ
admet-2088	753	97	gum	gum	NOUN
admet-2088	753	98	arabic	arabic	ADJ
admet-2088	753	99	-	-	PUNCT
admet-2088	753	100	gold	gold	NOUN
admet-2088	753	101	nanorod	nanorod	ADJ
admet-2088	753	102	composite	composite	NOUN
admet-2088	753	103	as	as	ADP
admet-2088	753	104	an	an	DET
admet-2088	753	105	effective	effective	ADJ
admet-2088	753	106	therapy	therapy	NOUN
admet-2088	753	107	for	for	ADP
admet-2088	753	108	mistreated	mistreat	VERB
admet-2088	753	109	melanomas	melanoma	NOUN
admet-2088	753	110	.	.	PUNCT
admet-2088	754	1	international	international	ADJ
admet-2088	754	2	journal	journal	PROPN
admet-2088	754	3	of	of	ADP
admet-2088	754	4	biological	biological	ADJ
admet-2088	754	5	macromolecules	macromolecule	NOUN
admet-2088	754	6	185	185	NUM
admet-2088	754	7	(	(	PUNCT
admet-2088	754	8	2021	2021	NUM
admet-2088	754	9	)	)	PUNCT
admet-2088	754	10	551	551	NUM
admet-2088	754	11	-	-	SYM
admet-2088	754	12	561	561	NUM
admet-2088	754	13	.	.	PUNCT
admet-2088	754	14	https://doi.org/10.1016/j.ijbiomac.2021.06.172	https://doi.org/10.1016/j.ijbiomac.2021.06.172	NOUN
admet-2088	754	15	.	.	PUNCT
admet-2088	755	1	[	[	X
admet-2088	755	2	10	10	NUM
admet-2088	755	3	]	]	X
admet-2088	755	4	r.	r.	PROPN
admet-2088	755	5	cassano	cassano	PROPN
admet-2088	755	6	,	,	PUNCT
admet-2088	755	7	m.	m.	NOUN
admet-2088	755	8	cuconato	cuconato	PROPN
admet-2088	755	9	,	,	PUNCT
admet-2088	755	10	g.	g.	PROPN
admet-2088	755	11	calviello	calviello	PROPN
admet-2088	755	12	,	,	PUNCT
admet-2088	755	13	s.	s.	PROPN
admet-2088	755	14	serini	serini	PROPN
admet-2088	755	15	,	,	PUNCT
admet-2088	755	16	s.	s.	PROPN
admet-2088	755	17	trombino	trombino	PROPN
admet-2088	755	18	.	.	PUNCT
admet-2088	756	1	recent	recent	ADJ
admet-2088	756	2	advances	advance	NOUN
admet-2088	756	3	in	in	ADP
admet-2088	756	4	nanotechnology	nanotechnology	NOUN
admet-2088	756	5	for	for	ADP
admet-2088	756	6	the	the	DET
admet-2088	756	7	treatment	treatment	NOUN
admet-2088	756	8	of	of	ADP
admet-2088	756	9	melanoma	melanoma	NOUN
admet-2088	756	10	.	.	PUNCT
admet-2088	757	1	molecules	molecule	NOUN
admet-2088	757	2	26	26	NUM
admet-2088	757	3	(	(	PUNCT
admet-2088	757	4	2021	2021	NUM
admet-2088	757	5	)	)	PUNCT
admet-2088	757	6	785	785	NUM
admet-2088	757	7	.	.	PUNCT
admet-2088	758	1	https://doi.org/10.3390/molecules26040785	https://doi.org/10.3390/molecules26040785	PROPN
admet-2088	758	2	.	.	PUNCT
admet-2088	759	1	[	[	X
admet-2088	759	2	11	11	NUM
admet-2088	759	3	]	]	X
admet-2088	759	4	a.p	a.p	PROPN
admet-2088	759	5	.	.	PROPN
admet-2088	759	6	cordeiro	cordeiro	PROPN
admet-2088	759	7	,	,	PUNCT
admet-2088	759	8	p.e	p.e	PROPN
admet-2088	759	9	.	.	PROPN
admet-2088	759	10	feuser	feuser	PROPN
admet-2088	759	11	,	,	PUNCT
admet-2088	759	12	p.g	p.g	PROPN
admet-2088	759	13	.	.	PROPN
admet-2088	759	14	figueiredo	figueiredo	PROPN
admet-2088	759	15	,	,	PUNCT
admet-2088	759	16	e.s	e.s	PROPN
admet-2088	759	17	.	.	PROPN
admet-2088	759	18	da	da	PROPN
admet-2088	759	19	cunha	cunha	PROPN
admet-2088	759	20	,	,	PUNCT
admet-2088	759	21	g.r	g.r	PROPN
admet-2088	759	22	.	.	PROPN
admet-2088	759	23	martinez	martinez	PROPN
admet-2088	759	24	,	,	PUNCT
admet-2088	759	25	r.a	r.a	PROPN
admet-2088	759	26	.	.	PROPN
admet-2088	759	27	machado	machado	PROPN
admet-2088	759	28	-	-	PUNCT
admet-2088	759	29	de	de	PROPN
admet-2088	759	30	-	-	PROPN
admet-2088	759	31	avila	avila	PROPN
admet-2088	759	32	,	,	PUNCT
admet-2088	759	33	m.e.m	m.e.m	PROPN
admet-2088	759	34	.	.	PUNCT
admet-2088	759	35	rocha	rocha	PROPN
admet-2088	759	36	,	,	PUNCT
admet-2088	759	37	p.h.h	p.h.h	NOUN
admet-2088	759	38	.	.	PUNCT
admet-2088	759	39	de	de	X
admet-2088	759	40	araújo	araújo	PROPN
admet-2088	759	41	,	,	PUNCT
admet-2088	759	42	c.	c.	PROPN
admet-2088	759	43	sayer	sayer	PROPN
admet-2088	759	44	.	.	PUNCT
admet-2088	760	1	in	in	ADP
admet-2088	760	2	vitro	vitro	X
admet-2088	760	3	synergic	synergic	ADJ
admet-2088	760	4	activity	activity	NOUN
admet-2088	760	5	of	of	ADP
admet-2088	760	6	diethyldithiocarbamate	diethyldithiocarbamate	NOUN
admet-2088	760	7	and	and	CCONJ
admet-2088	760	8	4nitrochalcone	4nitrochalcone	NUM
admet-2088	760	9	loaded	load	VERB
admet-2088	760	10	in	in	ADP
admet-2088	760	11	beeswax	beeswax	NOUN
admet-2088	760	12	nanoparticles	nanoparticle	NOUN
admet-2088	760	13	against	against	ADP
admet-2088	760	14	melanoma	melanoma	NOUN
admet-2088	760	15	(	(	PUNCT
admet-2088	760	16	b16f10	b16f10	ADJ
admet-2088	760	17	)	)	PUNCT
admet-2088	760	18	cells	cell	NOUN
admet-2088	760	19	.	.	PUNCT
admet-2088	761	1	materials	material	NOUN
admet-2088	761	2	science	science	PROPN
admet-2088	761	3	&	&	CCONJ
admet-2088	761	4	engineering	engineering	PROPN
admet-2088	761	5	c	c	PROPN
admet-2088	761	6	120	120	NUM
admet-2088	761	7	(	(	PUNCT
admet-2088	761	8	2021	2021	NUM
admet-2088	761	9	)	)	PUNCT
admet-2088	761	10	111651	111651	NUM
admet-2088	761	11	.	.	PUNCT
admet-2088	762	1	https://doi.org/10.1016/j.msec.2020.111651	https://doi.org/10.1016/j.msec.2020.111651	NOUN
admet-2088	762	2	.	.	PUNCT
admet-2088	763	1	[	[	X
admet-2088	763	2	12	12	NUM
admet-2088	763	3	]	]	PUNCT
admet-2088	763	4	q.	q.	PROPN
admet-2088	763	5	liu	liu	PROPN
admet-2088	763	6	,	,	PUNCT
admet-2088	763	7	m.	m.	NOUN
admet-2088	763	8	das	das	PROPN
admet-2088	763	9	,	,	PUNCT
admet-2088	763	10	y.	y.	PROPN
admet-2088	763	11	liu	liu	PROPN
admet-2088	763	12	,	,	PUNCT
admet-2088	763	13	l.	l.	PROPN
admet-2088	763	14	huang	huang	PROPN
admet-2088	763	15	.	.	PROPN
admet-2088	763	16	targeted	target	VERB
admet-2088	763	17	drug	drug	NOUN
admet-2088	763	18	delivery	delivery	NOUN
admet-2088	763	19	to	to	ADP
admet-2088	763	20	melanoma	melanoma	VERB
admet-2088	763	21	.	.	PUNCT
admet-2088	764	1	advanced	advanced	ADJ
admet-2088	764	2	drug	drug	NOUN
admet-2088	764	3	delivery	delivery	NOUN
admet-2088	764	4	reviews	review	VERB
admet-2088	764	5	127	127	NUM
admet-2088	764	6	(	(	PUNCT
admet-2088	764	7	2018	2018	NUM
admet-2088	764	8	)	)	PUNCT
admet-2088	764	9	208	208	NUM
admet-2088	764	10	-	-	SYM
admet-2088	764	11	221	221	NUM
admet-2088	764	12	.	.	PUNCT
admet-2088	765	1	https://doi.org/10.1016/j.addr.2017.09.016	https://doi.org/10.1016/j.addr.2017.09.016	NUM
admet-2088	765	2	.	.	PUNCT
admet-2088	766	1	[	[	X
admet-2088	766	2	13	13	NUM
admet-2088	766	3	]	]	X
admet-2088	766	4	c.e	c.e	PROPN
admet-2088	766	5	.	.	PROPN
admet-2088	766	6	desantis	desantis	PROPN
admet-2088	766	7	,	,	PUNCT
admet-2088	766	8	c.c	c.c	PROPN
admet-2088	766	9	.	.	PROPN
admet-2088	766	10	lin	lin	PROPN
admet-2088	766	11	,	,	PUNCT
admet-2088	766	12	a.b	a.b	PROPN
admet-2088	766	13	.	.	PROPN
admet-2088	766	14	mariotto	mariotto	NOUN
admet-2088	766	15	,	,	PUNCT
admet-2088	766	16	r.l	r.l	PROPN
admet-2088	766	17	.	.	PROPN
admet-2088	766	18	siegel	siegel	PROPN
admet-2088	766	19	,	,	PUNCT
admet-2088	766	20	k.d	k.d	PROPN
admet-2088	766	21	.	.	PROPN
admet-2088	766	22	stein	stein	PROPN
admet-2088	766	23	,	,	PUNCT
admet-2088	766	24	j.l	j.l	PROPN
admet-2088	766	25	.	.	PROPN
admet-2088	766	26	kramer	kramer	PROPN
admet-2088	766	27	,	,	PUNCT
admet-2088	766	28	r.	r.	PROPN
admet-2088	766	29	alteri	alteri	PROPN
admet-2088	766	30	,	,	PUNCT
admet-2088	766	31	a.s	a.s	PROPN
admet-2088	766	32	.	.	PROPN
admet-2088	766	33	robbins	robbins	PROPN
admet-2088	766	34	,	,	PUNCT
admet-2088	766	35	a.	a.	NOUN
admet-2088	766	36	jemal	jemal	PROPN
admet-2088	766	37	.	.	PUNCT
admet-2088	767	1	cancer	cancer	NOUN
admet-2088	767	2	treatment	treatment	NOUN
admet-2088	767	3	and	and	CCONJ
admet-2088	767	4	survivorship	survivorship	NOUN
admet-2088	767	5	statistics	statistic	NOUN
admet-2088	767	6	,	,	PUNCT
admet-2088	767	7	2014	2014	NUM
admet-2088	767	8	.	.	PUNCT
admet-2088	768	1	ca	ca	NOUN
admet-2088	768	2	.	.	PUNCT
admet-2088	769	1	a	a	DET
admet-2088	769	2	cancer	cancer	NOUN
admet-2088	769	3	journal	journal	NOUN
admet-2088	769	4	for	for	ADP
admet-2088	769	5	clinicians	clinician	NOUN
admet-2088	769	6	64	64	NUM
admet-2088	769	7	(	(	PUNCT
admet-2088	769	8	2014	2014	NUM
admet-2088	769	9	)	)	PUNCT
admet-2088	769	10	252	252	NUM
admet-2088	769	11	-	-	SYM
admet-2088	769	12	271	271	NUM
admet-2088	769	13	.	.	X
admet-2088	769	14	https://doi.org/10.3322/caac.21235	https://doi.org/10.3322/caac.21235	NOUN
admet-2088	769	15	.	.	PUNCT
admet-2088	770	1	[	[	X
admet-2088	770	2	14	14	NUM
admet-2088	770	3	]	]	X
admet-2088	770	4	s.j	s.j	PROPN
admet-2088	770	5	.	.	PROPN
admet-2088	770	6	welsh	welsh	PROPN
admet-2088	770	7	,	,	PUNCT
admet-2088	770	8	p.g	p.g	PROPN
admet-2088	770	9	.	.	PROPN
admet-2088	770	10	corrie	corrie	PROPN
admet-2088	770	11	.	.	PUNCT
admet-2088	771	1	management	management	NOUN
admet-2088	771	2	of	of	ADP
admet-2088	771	3	braf	braf	NOUN
admet-2088	771	4	and	and	CCONJ
admet-2088	771	5	mek	mek	PROPN
admet-2088	771	6	inhibitor	inhibitor	NOUN
admet-2088	771	7	toxicities	toxicity	NOUN
admet-2088	771	8	in	in	ADP
admet-2088	771	9	patients	patient	NOUN
admet-2088	771	10	with	with	ADP
admet-2088	771	11	metastatic	metastatic	ADJ
admet-2088	771	12	melanoma	melanoma	NOUN
admet-2088	771	13	.	.	PUNCT
admet-2088	772	1	therapeutic	therapeutic	ADJ
admet-2088	772	2	advances	advance	NOUN
admet-2088	772	3	in	in	ADP
admet-2088	772	4	medical	medical	ADJ
admet-2088	772	5	oncology	oncology	NOUN
admet-2088	772	6	7	7	NUM
admet-2088	772	7	(	(	PUNCT
admet-2088	772	8	2015	2015	NUM
admet-2088	772	9	)	)	PUNCT
admet-2088	772	10	122	122	NUM
admet-2088	772	11	-	-	SYM
admet-2088	772	12	136	136	NUM
admet-2088	772	13	.	.	PUNCT
admet-2088	773	1	https://doi.org/10.1177/1758834014566428	https://doi.org/10.1177/1758834014566428	NOUN
admet-2088	773	2	.	.	PUNCT
admet-2088	774	1	https://www.nature.com/articles/s41598-020-68994-0	https://www.nature.com/articles/s41598-020-68994-0	PROPN
admet-2088	774	2	https://www.nature.com/articles/s41598-020-68994-0	https://www.nature.com/articles/s41598-020-68994-0	VERB
admet-2088	774	3	https://doi.org/10.2147/ijn.s176737	https://doi.org/10.2147/ijn.s176737	PROPN
admet-2088	775	1	https://doi.org/10.1021/acsnano.9b08133	https://doi.org/10.1021/acsnano.9b08133	NOUN
admet-2088	775	2	https://doi.org/10.1186/s40580-019-0193-2	https://doi.org/10.1186/s40580-019-0193-2	PROPN
admet-2088	776	1	https://doi.org/10.1016/j.nano.2022.102613	https://doi.org/10.1016/j.nano.2022.102613	PROPN
admet-2088	776	2	https://doi.org/10.1001/jamadermatol.2022.0160	https://doi.org/10.1001/jamadermatol.2022.0160	PROPN
admet-2088	776	3	https://doi.org/10.1016/j.ejps.2022.106311	https://doi.org/10.1016/j.ejps.2022.106311	PROPN
admet-2088	776	4	https://doi.org/10.3322/caac.21492	https://doi.org/10.3322/caac.21492	PROPN
admet-2088	776	5	https://doi.org/10.1016/j.ijbiomac.2021.06.172	https://doi.org/10.1016/j.ijbiomac.2021.06.172	NOUN
admet-2088	776	6	file:///d:/zoranm	file:///d:/zoranm	PROPN
admet-2088	776	7	/	/	SYM
admet-2088	776	8	downloads/.%20https:/doi.org/10.3390	downloads/.%20https:/doi.org/10.3390	PROPN
admet-2088	776	9	/	/	SYM
admet-2088	776	10	molecules26040785	molecules26040785	PROPN
admet-2088	776	11	file:///d:/zoranm	file:///d:/zoranm	PROPN
admet-2088	776	12	/	/	SYM
admet-2088	776	13	downloads/.%20https:/doi.org/10.3390	downloads/.%20https:/doi.org/10.3390	PROPN
admet-2088	776	14	/	/	SYM
admet-2088	776	15	molecules26040785	molecules26040785	PROPN
admet-2088	776	16	https://doi.org/10.1016/j.msec.2020.111651	https://doi.org/10.1016/j.msec.2020.111651	NOUN
admet-2088	776	17	https://doi.org/10.1016/j.addr.2017.09.016	https://doi.org/10.1016/j.addr.2017.09.016	PROPN
admet-2088	776	18	https://doi.org/10.3322/caac.21235	https://doi.org/10.3322/caac.21235	NOUN
admet-2088	776	19	https://doi.org/10.1177/1758834014566428	https://doi.org/10.1177/1758834014566428	ADP
admet-2088	776	20	admet	admet	PROPN
admet-2088	776	21	&	&	CCONJ
admet-2088	776	22	dmpk	dmpk	PROPN
admet-2088	776	23	12(1	12(1	PROPN
admet-2088	776	24	)	)	PUNCT
admet-2088	776	25	(	(	PUNCT
admet-2088	776	26	2024	2024	NUM
admet-2088	776	27	)	)	PUNCT
admet-2088	776	28	107	107	NUM
admet-2088	776	29	-	-	SYM
admet-2088	776	30	150	150	NUM
admet-2088	776	31	nanomaterial	nanomaterial	NOUN
admet-2088	776	32	-	-	PUNCT
admet-2088	776	33	based	base	VERB
admet-2088	776	34	drug	drug	NOUN
admet-2088	776	35	delivery	delivery	NOUN
admet-2088	776	36	systems	system	NOUN
admet-2088	776	37	for	for	ADP
admet-2088	776	38	melanoma	melanoma	NOUN
admet-2088	776	39	therapy	therapy	NOUN
admet-2088	776	40	doi	doi	NOUN
admet-2088	776	41	:	:	PUNCT
admet-2088	776	42	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	776	43	137	137	NUM
admet-2088	776	44	[	[	SYM
admet-2088	776	45	15	15	NUM
admet-2088	776	46	]	]	X
admet-2088	776	47	s.a	s.a	PROPN
admet-2088	776	48	.	.	PROPN
admet-2088	776	49	blankenstein	blankenstein	PROPN
admet-2088	776	50	,	,	PUNCT
admet-2088	776	51	a.c.j	a.c.j	NOUN
admet-2088	776	52	.	.	PUNCT
admet-2088	777	1	van	van	PROPN
admet-2088	777	2	akkooi	akkooi	PROPN
admet-2088	777	3	.	.	PUNCT
admet-2088	778	1	adjuvant	adjuvant	ADJ
admet-2088	778	2	systemic	systemic	ADJ
admet-2088	778	3	therapy	therapy	NOUN
admet-2088	778	4	in	in	ADP
admet-2088	778	5	high	high	ADJ
admet-2088	778	6	-	-	PUNCT
admet-2088	778	7	risk	risk	NOUN
admet-2088	778	8	melanoma	melanoma	NOUN
admet-2088	778	9	.	.	PUNCT
admet-2088	779	1	melanoma	melanoma	PROPN
admet-2088	779	2	research	research	NOUN
admet-2088	779	3	29	29	NUM
admet-2088	779	4	(	(	PUNCT
admet-2088	779	5	2019	2019	NUM
admet-2088	779	6	)	)	PUNCT
admet-2088	779	7	358	358	NUM
admet-2088	779	8	-	-	SYM
admet-2088	779	9	364	364	NUM
admet-2088	779	10	.	.	PUNCT
admet-2088	780	1	https://doi.org/10.1097/cmr.0000000000000604	https://doi.org/10.1097/cmr.0000000000000604	PROPN
admet-2088	780	2	.	.	PUNCT
admet-2088	781	1	[	[	X
admet-2088	781	2	16	16	NUM
admet-2088	781	3	]	]	X
admet-2088	781	4	national	national	PROPN
admet-2088	781	5	cancer	cancer	PROPN
admet-2088	781	6	institute	institute	PROPN
admet-2088	781	7	,	,	PUNCT
admet-2088	781	8	drugs	drug	NOUN
admet-2088	781	9	approved	approve	VERB
admet-2088	781	10	for	for	ADP
admet-2088	781	11	skin	skin	NOUN
admet-2088	781	12	cancer	cancer	NOUN
admet-2088	781	13	,	,	PUNCT
admet-2088	781	14	https://www.cancer.gov/aboutcancer/treatment/drugs/skin	https://www.cancer.gov/aboutcancer/treatment/drugs/skin	PROPN
admet-2088	781	15	.	.	PUNCT
admet-2088	782	1	august	august	PROPN
admet-2088	782	2	16	16	NUM
admet-2088	782	3	,	,	PUNCT
admet-2088	782	4	2023	2023	NUM
admet-2088	782	5	.	.	PUNCT
admet-2088	783	1	[	[	X
admet-2088	783	2	17	17	NUM
admet-2088	783	3	]	]	PUNCT
admet-2088	783	4	j.	j.	PROPN
admet-2088	783	5	berk	berk	PROPN
admet-2088	783	6	-	-	PUNCT
admet-2088	783	7	krauss	krauss	PROPN
admet-2088	783	8	,	,	PUNCT
admet-2088	783	9	j.a	j.a	PROPN
admet-2088	783	10	.	.	PROPN
admet-2088	783	11	stein	stein	PROPN
admet-2088	783	12	,	,	PUNCT
admet-2088	783	13	j.	j.	PROPN
admet-2088	783	14	weber	weber	PROPN
admet-2088	783	15	,	,	PUNCT
admet-2088	783	16	d.	d.	PROPN
admet-2088	783	17	polsky	polsky	PROPN
admet-2088	783	18	,	,	PUNCT
admet-2088	783	19	a.c	a.c	PROPN
admet-2088	783	20	.	.	PROPN
admet-2088	783	21	geller	geller	PROPN
admet-2088	783	22	,	,	PUNCT
admet-2088	783	23	new	new	ADJ
admet-2088	783	24	systematic	systematic	ADJ
admet-2088	783	25	therapies	therapy	NOUN
admet-2088	783	26	and	and	CCONJ
admet-2088	783	27	trends	trend	NOUN
admet-2088	783	28	in	in	ADP
admet-2088	783	29	cutaneous	cutaneous	ADJ
admet-2088	783	30	melanoma	melanoma	NOUN
admet-2088	783	31	deaths	death	NOUN
admet-2088	783	32	among	among	ADP
admet-2088	783	33	us	us	PROPN
admet-2088	783	34	whites	white	NOUN
admet-2088	783	35	,	,	PUNCT
admet-2088	783	36	1986	1986	NUM
admet-2088	783	37	-	-	SYM
admet-2088	783	38	2016	2016	NUM
admet-2088	783	39	.	.	PUNCT
admet-2088	784	1	american	american	ADJ
admet-2088	784	2	journal	journal	PROPN
admet-2088	784	3	of	of	ADP
admet-2088	784	4	public	public	ADJ
admet-2088	784	5	health	health	NOUN
admet-2088	784	6	110	110	NUM
admet-2088	784	7	(	(	PUNCT
admet-2088	784	8	2020	2020	NUM
admet-2088	784	9	)	)	PUNCT
admet-2088	784	10	731	731	NUM
admet-2088	784	11	-	-	SYM
admet-2088	784	12	733	733	NUM
admet-2088	784	13	.	.	PUNCT
admet-2088	785	1	https://doi.org/10.2105/ajph.2020.305567	https://doi.org/10.2105/ajph.2020.305567	X
admet-2088	785	2	.	.	PUNCT
admet-2088	786	1	[	[	X
admet-2088	786	2	18	18	NUM
admet-2088	786	3	]	]	PUNCT
admet-2088	786	4	z.	z.	PROPN
admet-2088	786	5	payandeh	payandeh	PROPN
admet-2088	786	6	,	,	PUNCT
admet-2088	786	7	m.	m.	NOUN
admet-2088	786	8	yarahmadi	yarahmadi	PROPN
admet-2088	786	9	,	,	PUNCT
admet-2088	786	10	z.	z.	PROPN
admet-2088	786	11	nariman	nariman	PROPN
admet-2088	786	12	-	-	PUNCT
admet-2088	786	13	saleh	saleh	PROPN
admet-2088	786	14	-	-	PUNCT
admet-2088	786	15	fam	fam	NOUN
admet-2088	786	16	,	,	PUNCT
admet-2088	786	17	v.	v.	CCONJ
admet-2088	786	18	tarhriz	tarhriz	NOUN
admet-2088	786	19	,	,	PUNCT
admet-2088	786	20	m.	m.	NOUN
admet-2088	786	21	islami	islami	PROPN
admet-2088	786	22	,	,	PUNCT
admet-2088	786	23	a.m.	a.m.	NOUN
admet-2088	786	24	aghdam	aghdam	PROPN
admet-2088	786	25	,	,	PUNCT
admet-2088	786	26	s.	s.	PROPN
admet-2088	786	27	eyvazi	eyvazi	PROPN
admet-2088	786	28	.	.	PUNCT
admet-2088	786	29	immune	immune	ADJ
admet-2088	786	30	therapy	therapy	NOUN
admet-2088	786	31	of	of	ADP
admet-2088	786	32	melanoma	melanoma	NOUN
admet-2088	786	33	:	:	PUNCT
admet-2088	786	34	overview	overview	NOUN
admet-2088	786	35	of	of	ADP
admet-2088	786	36	therapeutic	therapeutic	ADJ
admet-2088	786	37	vaccines	vaccine	NOUN
admet-2088	786	38	.	.	PUNCT
admet-2088	787	1	journal	journal	NOUN
admet-2088	787	2	of	of	ADP
admet-2088	787	3	cellular	cellular	ADJ
admet-2088	787	4	physiology	physiology	NOUN
admet-2088	787	5	234	234	NUM
admet-2088	787	6	(	(	PUNCT
admet-2088	787	7	2019	2019	NUM
admet-2088	787	8	)	)	PUNCT
admet-2088	787	9	14612	14612	NUM
admet-2088	787	10	-	-	SYM
admet-2088	787	11	14621	14621	NUM
admet-2088	787	12	.	.	PUNCT
admet-2088	788	1	https://doi.org/10.1002/jcp.28181	https://doi.org/10.1002/jcp.28181	PROPN
admet-2088	788	2	.	.	PUNCT
admet-2088	789	1	[	[	X
admet-2088	789	2	19	19	NUM
admet-2088	789	3	]	]	PUNCT
admet-2088	789	4	b.	b.	PROPN
admet-2088	789	5	zhao	zhao	PROPN
admet-2088	789	6	,	,	PUNCT
admet-2088	789	7	y.-y	y.-y	VERB
admet-2088	789	8	.	.	PUNCT
admet-2088	790	1	he	he	PRON
admet-2088	790	2	.	.	PUNCT
admet-2088	791	1	recent	recent	ADJ
admet-2088	791	2	advances	advance	NOUN
admet-2088	791	3	in	in	ADP
admet-2088	791	4	the	the	DET
admet-2088	791	5	prevention	prevention	NOUN
admet-2088	791	6	and	and	CCONJ
admet-2088	791	7	treatment	treatment	NOUN
admet-2088	791	8	of	of	ADP
admet-2088	791	9	skin	skin	NOUN
admet-2088	791	10	cancer	cancer	NOUN
admet-2088	791	11	using	use	VERB
admet-2088	791	12	photodynamic	photodynamic	ADJ
admet-2088	791	13	therapy	therapy	NOUN
admet-2088	791	14	.	.	PUNCT
admet-2088	792	1	expert	expert	NOUN
admet-2088	792	2	review	review	NOUN
admet-2088	792	3	of	of	ADP
admet-2088	792	4	anticancer	anticancer	NOUN
admet-2088	792	5	therapy	therapy	NOUN
admet-2088	792	6	10	10	NUM
admet-2088	792	7	(	(	PUNCT
admet-2088	792	8	2010	2010	NUM
admet-2088	792	9	)	)	PUNCT
admet-2088	792	10	1797	1797	NUM
admet-2088	792	11	-	-	SYM
admet-2088	792	12	1809	1809	NUM
admet-2088	792	13	.	.	PUNCT
admet-2088	793	1	https://doi.org/10.1586/era.10.154	https://doi.org/10.1586/era.10.154	VERB
admet-2088	793	2	.	.	PUNCT
admet-2088	794	1	[	[	X
admet-2088	794	2	20	20	NUM
admet-2088	794	3	]	]	X
admet-2088	794	4	y.	y.	PROPN
admet-2088	794	5	zeng	zeng	PROPN
admet-2088	794	6	,	,	PUNCT
admet-2088	794	7	j.	j.	PROPN
admet-2088	794	8	chen	chen	PROPN
admet-2088	794	9	,	,	PUNCT
admet-2088	794	10	z.	z.	PROPN
admet-2088	794	11	tian	tian	PROPN
admet-2088	794	12	,	,	PUNCT
admet-2088	794	13	m.	m.	PROPN
admet-2088	794	14	zhu	zhu	PROPN
admet-2088	794	15	,	,	PUNCT
admet-2088	794	16	y.	y.	PROPN
admet-2088	794	17	zhu	zhu	PROPN
admet-2088	794	18	.	.	PUNCT
admet-2088	795	1	preparation	preparation	NOUN
admet-2088	795	2	of	of	ADP
admet-2088	795	3	mesoporous	mesoporous	ADJ
admet-2088	795	4	organosilica	organosilica	NOUN
admet-2088	795	5	based	base	VERB
admet-2088	795	6	nanosystem	nanosystem	NOUN
admet-2088	795	7	for	for	ADP
admet-2088	795	8	in	in	ADP
admet-2088	795	9	vitro	vitro	X
admet-2088	795	10	synergistic	synergistic	ADJ
admet-2088	795	11	chemoand	chemoand	ADJ
admet-2088	795	12	photothermal	photothermal	ADJ
admet-2088	795	13	therapy	therapy	NOUN
admet-2088	795	14	.	.	PUNCT
admet-2088	796	1	journal	journal	PROPN
admet-2088	796	2	of	of	ADP
admet-2088	796	3	inorganic	inorganic	ADJ
admet-2088	796	4	materials	material	NOUN
admet-2088	796	5	35	35	NUM
admet-2088	796	6	(	(	PUNCT
admet-2088	796	7	2020	2020	NUM
admet-2088	796	8	)	)	PUNCT
admet-2088	796	9	1365	1365	NUM
admet-2088	796	10	-	-	SYM
admet-2088	796	11	1372	1372	NUM
admet-2088	796	12	.	.	PUNCT
admet-2088	797	1	https://doi.org/10.15541/jim20200091	https://doi.org/10.15541/jim20200091	ADJ
admet-2088	797	2	.	.	PUNCT
admet-2088	798	1	[	[	X
admet-2088	798	2	21	21	NUM
admet-2088	798	3	]	]	PUNCT
admet-2088	798	4	j.	j.	PROPN
admet-2088	798	5	chen	chen	PROPN
admet-2088	798	6	,	,	PUNCT
admet-2088	798	7	y.	y.	PROPN
admet-2088	798	8	cao	cao	PROPN
admet-2088	798	9	,	,	PUNCT
admet-2088	798	10	s.	s.	PROPN
admet-2088	798	11	lin	lin	PROPN
admet-2088	798	12	,	,	PUNCT
admet-2088	798	13	h.	h.	PROPN
admet-2088	798	14	niu	niu	PROPN
admet-2088	798	15	,	,	PUNCT
admet-2088	798	16	h.	h.	PROPN
admet-2088	798	17	zhang	zhang	PROPN
admet-2088	798	18	,	,	PUNCT
admet-2088	798	19	l.	l.	PROPN
admet-2088	798	20	guan	guan	PROPN
admet-2088	798	21	,	,	PUNCT
admet-2088	798	22	c.	c.	PROPN
admet-2088	798	23	shu	shu	PROPN
admet-2088	798	24	,	,	PUNCT
admet-2088	798	25	a.	a.	PROPN
admet-2088	798	26	wu	wu	PROPN
admet-2088	798	27	,	,	PUNCT
admet-2088	798	28	y.	y.	PROPN
admet-2088	798	29	bian	bian	PROPN
admet-2088	798	30	,	,	PUNCT
admet-2088	798	31	y.	y.	PROPN
admet-2088	798	32	zhu	zhu	PROPN
admet-2088	798	33	.	.	PUNCT
admet-2088	799	1	a	a	DET
admet-2088	799	2	responsive	responsive	ADJ
admet-2088	799	3	microneedle	microneedle	NOUN
admet-2088	799	4	system	system	NOUN
admet-2088	799	5	for	for	ADP
admet-2088	799	6	efficient	efficient	ADJ
admet-2088	799	7	anti	anti	ADJ
admet-2088	799	8	-	-	NOUN
admet-2088	799	9	melanoma	melanoma	ADJ
admet-2088	799	10	by	by	ADP
admet-2088	799	11	combining	combine	VERB
admet-2088	799	12	self	self	NOUN
admet-2088	799	13	-	-	PUNCT
admet-2088	799	14	enhanced	enhance	VERB
admet-2088	799	15	chemodynamic	chemodynamic	ADJ
admet-2088	799	16	therapy	therapy	NOUN
admet-2088	799	17	with	with	ADP
admet-2088	799	18	photothermal	photothermal	ADJ
admet-2088	799	19	therapy	therapy	NOUN
admet-2088	799	20	.	.	PUNCT
admet-2088	800	1	chemical	chemical	PROPN
admet-2088	800	2	engineering	engineering	PROPN
admet-2088	800	3	journal	journal	PROPN
admet-2088	800	4	431	431	NUM
admet-2088	800	5	(	(	PUNCT
admet-2088	800	6	2022	2022	NUM
admet-2088	800	7	)	)	PUNCT
admet-2088	800	8	133466	133466	NUM
admet-2088	800	9	.	.	PUNCT
admet-2088	801	1	https://doi.org/10.1016/j.cej.2021.133466	https://doi.org/10.1016/j.cej.2021.133466	PROPN
admet-2088	801	2	.	.	PUNCT
admet-2088	802	1	[	[	X
admet-2088	802	2	22	22	NUM
admet-2088	802	3	]	]	PUNCT
admet-2088	802	4	t.	t.	PROPN
admet-2088	802	5	sun	sun	PROPN
admet-2088	802	6	,	,	PUNCT
admet-2088	802	7	y.s	y.s	PROPN
admet-2088	802	8	.	.	PROPN
admet-2088	802	9	zhang	zhang	PROPN
admet-2088	802	10	,	,	PUNCT
admet-2088	802	11	b.	b.	PROPN
admet-2088	802	12	pang	pang	PROPN
admet-2088	802	13	,	,	PUNCT
admet-2088	802	14	d.c	d.c	PROPN
admet-2088	802	15	.	.	PUNCT
admet-2088	802	16	hyun	hyun	PROPN
admet-2088	802	17	,	,	PUNCT
admet-2088	802	18	m.	m.	PROPN
admet-2088	802	19	yang	yang	PROPN
admet-2088	802	20	,	,	PUNCT
admet-2088	802	21	y.	y.	PROPN
admet-2088	802	22	xia	xia	PROPN
admet-2088	802	23	,	,	PUNCT
admet-2088	802	24	engineered	engineer	VERB
admet-2088	802	25	nanoparticles	nanoparticle	NOUN
admet-2088	802	26	for	for	ADP
admet-2088	802	27	drug	drug	NOUN
admet-2088	802	28	delivery	delivery	NOUN
admet-2088	802	29	in	in	ADP
admet-2088	802	30	cancer	cancer	NOUN
admet-2088	802	31	therapy	therapy	NOUN
admet-2088	802	32	,	,	PUNCT
admet-2088	802	33	angewandte	angewandte	PROPN
admet-2088	802	34	chemie	chemie	PROPN
admet-2088	802	35	53	53	NUM
admet-2088	802	36	(	(	PUNCT
admet-2088	802	37	2014	2014	NUM
admet-2088	802	38	)	)	PUNCT
admet-2088	802	39	12320	12320	NUM
admet-2088	802	40	-	-	SYM
admet-2088	802	41	12364	12364	NUM
admet-2088	802	42	.	.	PUNCT
admet-2088	803	1	https://doi.org/10.1002/anie.201403036	https://doi.org/10.1002/anie.201403036	NOUN
admet-2088	803	2	.	.	PUNCT
admet-2088	804	1	[	[	X
admet-2088	804	2	23	23	NUM
admet-2088	804	3	]	]	X
admet-2088	804	4	a.z	a.z	PROPN
admet-2088	804	5	.	.	PROPN
admet-2088	804	6	wilczewska	wilczewska	PROPN
admet-2088	804	7	,	,	PUNCT
admet-2088	804	8	k.	k.	PROPN
admet-2088	804	9	niemirowicz	niemirowicz	PROPN
admet-2088	804	10	,	,	PUNCT
admet-2088	804	11	k.h	k.h	PROPN
admet-2088	804	12	.	.	PROPN
admet-2088	804	13	markiewicz	markiewicz	PROPN
admet-2088	804	14	,	,	PUNCT
admet-2088	804	15	h.	h.	PROPN
admet-2088	804	16	car	car	PROPN
admet-2088	804	17	,	,	PUNCT
admet-2088	804	18	nanoparticles	nanoparticle	NOUN
admet-2088	804	19	as	as	ADP
admet-2088	804	20	drug	drug	NOUN
admet-2088	804	21	delivery	delivery	NOUN
admet-2088	804	22	systems	system	NOUN
admet-2088	804	23	,	,	PUNCT
admet-2088	804	24	pharmacol	pharmacol	PROPN
admet-2088	804	25	.	.	PUNCT
admet-2088	805	1	rep	rep	PROPN
admet-2088	805	2	.	.	PROPN
admet-2088	805	3	64	64	NUM
admet-2088	805	4	(	(	PUNCT
admet-2088	805	5	2012	2012	NUM
admet-2088	805	6	)	)	PUNCT
admet-2088	805	7	1020	1020	NUM
admet-2088	805	8	-	-	SYM
admet-2088	805	9	1037	1037	NUM
admet-2088	805	10	.	.	PUNCT
admet-2088	806	1	https://doi.org/10.1016/s1734-1140(12)70901-5	https://doi.org/10.1016/s1734-1140(12)70901-5	NOUN
admet-2088	806	2	.	.	PUNCT
admet-2088	807	1	[	[	X
admet-2088	807	2	24	24	NUM
admet-2088	807	3	]	]	X
admet-2088	807	4	r.	r.	PROPN
admet-2088	807	5	singh	singh	PROPN
admet-2088	807	6	,	,	PUNCT
admet-2088	807	7	j.w	j.w	PROPN
admet-2088	807	8	.	.	PROPN
admet-2088	807	9	lillard	lillard	PROPN
admet-2088	807	10	jr	jr	PROPN
admet-2088	807	11	.	.	PROPN
admet-2088	807	12	nanoparticle	nanoparticle	NOUN
admet-2088	807	13	-	-	PUNCT
admet-2088	807	14	based	base	VERB
admet-2088	807	15	targeted	target	VERB
admet-2088	807	16	drug	drug	NOUN
admet-2088	807	17	delivery	delivery	NOUN
admet-2088	807	18	.	.	PUNCT
admet-2088	808	1	experimental	experimental	ADJ
admet-2088	808	2	and	and	CCONJ
admet-2088	808	3	molecular	molecular	ADJ
admet-2088	808	4	pathology	pathology	NOUN
admet-2088	808	5	86	86	NUM
admet-2088	808	6	(	(	PUNCT
admet-2088	808	7	2009	2009	NUM
admet-2088	808	8	)	)	PUNCT
admet-2088	808	9	215	215	NUM
admet-2088	808	10	-	-	SYM
admet-2088	808	11	223	223	NUM
admet-2088	808	12	.	.	PUNCT
admet-2088	808	13	https://doi.org/10.1016/j.yexmp.2008.12.004	https://doi.org/10.1016/j.yexmp.2008.12.004	NOUN
admet-2088	808	14	.	.	PUNCT
admet-2088	809	1	[	[	X
admet-2088	809	2	25	25	NUM
admet-2088	809	3	]	]	PUNCT
admet-2088	809	4	m.	m.	NOUN
admet-2088	809	5	pourmadadi	pourmadadi	PROPN
admet-2088	809	6	,	,	PUNCT
admet-2088	809	7	md	md	PROPN
admet-2088	809	8	.	.	PROPN
admet-2088	809	9	mahdi	mahdi	PROPN
admet-2088	809	10	eshaghi	eshaghi	PROPN
admet-2088	809	11	,	,	PUNCT
admet-2088	809	12	s.	s.	PROPN
admet-2088	809	13	ostovar	ostovar	PROPN
admet-2088	809	14	,	,	PUNCT
admet-2088	809	15	z.	z.	PROPN
admet-2088	809	16	mohammadi	mohammadi	PROPN
admet-2088	809	17	,	,	PUNCT
admet-2088	809	18	r.k	r.k	PROPN
admet-2088	809	19	.	.	PROPN
admet-2088	809	20	sharma	sharma	PROPN
admet-2088	809	21	,	,	PUNCT
admet-2088	809	22	a.c	a.c	PROPN
admet-2088	809	23	.	.	PROPN
admet-2088	809	24	paiva	paiva	NOUN
admet-2088	809	25	-	-	PUNCT
admet-2088	809	26	santos	santos	PROPN
admet-2088	809	27	,	,	PUNCT
admet-2088	809	28	e.	e.	PROPN
admet-2088	809	29	rahmani	rahmani	PROPN
admet-2088	809	30	,	,	PUNCT
admet-2088	809	31	a.	a.	PROPN
admet-2088	809	32	rahdar	rahdar	PROPN
admet-2088	809	33	,	,	PUNCT
admet-2088	809	34	s.	s.	PROPN
admet-2088	809	35	pandey	pandey	PROPN
admet-2088	809	36	.	.	PUNCT
admet-2088	810	1	innovative	innovative	ADJ
admet-2088	810	2	nanomaterials	nanomaterial	NOUN
admet-2088	810	3	for	for	ADP
admet-2088	810	4	cancer	cancer	NOUN
admet-2088	810	5	diagnosis	diagnosis	NOUN
admet-2088	810	6	,	,	PUNCT
admet-2088	810	7	imaging	imaging	NOUN
admet-2088	810	8	,	,	PUNCT
admet-2088	810	9	and	and	CCONJ
admet-2088	810	10	therapy	therapy	NOUN
admet-2088	810	11	:	:	PUNCT
admet-2088	810	12	drug	drug	NOUN
admet-2088	810	13	delivery	delivery	NOUN
admet-2088	810	14	applications	application	NOUN
admet-2088	810	15	.	.	PUNCT
admet-2088	811	1	journal	journal	NOUN
admet-2088	811	2	of	of	ADP
admet-2088	811	3	drug	drug	NOUN
admet-2088	811	4	delivery	delivery	NOUN
admet-2088	811	5	science	science	NOUN
admet-2088	811	6	and	and	CCONJ
admet-2088	811	7	technology	technology	NOUN
admet-2088	811	8	82	82	NUM
admet-2088	811	9	(	(	PUNCT
admet-2088	811	10	2023	2023	NUM
admet-2088	811	11	)	)	PUNCT
admet-2088	811	12	104357	104357	NUM
admet-2088	811	13	.	.	PUNCT
admet-2088	812	1	https://doi.org/10.1016/j.jddst.2023.104357	https://doi.org/10.1016/j.jddst.2023.104357	PROPN
admet-2088	812	2	.	.	PUNCT
admet-2088	813	1	[	[	X
admet-2088	813	2	26	26	NUM
admet-2088	813	3	]	]	PUNCT
admet-2088	813	4	t.	t.	PROPN
admet-2088	813	5	liu	liu	PROPN
admet-2088	813	6	,	,	PUNCT
admet-2088	813	7	y.	y.	PROPN
admet-2088	813	8	lu	lu	PROPN
admet-2088	813	9	,	,	PUNCT
admet-2088	813	10	r.	r.	PROPN
admet-2088	813	11	zhan	zhan	PROPN
admet-2088	813	12	,	,	PUNCT
admet-2088	813	13	w.	w.	PROPN
admet-2088	813	14	qian	qian	PROPN
admet-2088	813	15	,	,	PUNCT
admet-2088	813	16	g.	g.	PROPN
admet-2088	813	17	luo	luo	PROPN
admet-2088	813	18	.	.	PUNCT
admet-2088	813	19	nanomaterials	nanomaterial	NOUN
admet-2088	813	20	and	and	CCONJ
admet-2088	813	21	nanomaterials	nanomaterial	NOUN
admet-2088	813	22	-	-	PUNCT
admet-2088	813	23	based	base	VERB
admet-2088	813	24	drug	drug	NOUN
admet-2088	813	25	delivery	delivery	NOUN
admet-2088	813	26	to	to	PART
admet-2088	813	27	promote	promote	VERB
admet-2088	813	28	cutaneous	cutaneous	ADJ
admet-2088	813	29	wound	wound	NOUN
admet-2088	813	30	healing	healing	NOUN
admet-2088	813	31	.	.	PUNCT
admet-2088	814	1	advanced	advanced	ADJ
admet-2088	814	2	drug	drug	NOUN
admet-2088	814	3	delivery	delivery	NOUN
admet-2088	814	4	reviews	review	NOUN
admet-2088	814	5	193	193	NUM
admet-2088	814	6	(	(	PUNCT
admet-2088	814	7	2023	2023	NUM
admet-2088	814	8	)	)	PUNCT
admet-2088	814	9	114670	114670	NUM
admet-2088	814	10	.	.	PUNCT
admet-2088	815	1	https://doi.org/10.3390/nano12040618	https://doi.org/10.3390/nano12040618	PROPN
admet-2088	815	2	.	.	PUNCT
admet-2088	816	1	[	[	X
admet-2088	816	2	27	27	NUM
admet-2088	816	3	]	]	X
admet-2088	816	4	s.	s.	PROPN
admet-2088	816	5	alarifi	alarifi	PROPN
admet-2088	816	6	,	,	PUNCT
admet-2088	816	7	d.	d.	PROPN
admet-2088	816	8	ali	ali	PROPN
admet-2088	816	9	,	,	PUNCT
admet-2088	816	10	s.	s.	PROPN
admet-2088	816	11	alkahtani	alkahtani	PROPN
admet-2088	816	12	,	,	PUNCT
admet-2088	816	13	a.	a.	PROPN
admet-2088	816	14	verma	verma	PROPN
admet-2088	816	15	,	,	PUNCT
admet-2088	816	16	m.	m.	NOUN
admet-2088	816	17	ahamed	ahamed	PROPN
admet-2088	816	18	,	,	PUNCT
admet-2088	816	19	m.	m.	NOUN
admet-2088	816	20	ahmed	ahmed	PROPN
admet-2088	816	21	,	,	PUNCT
admet-2088	816	22	h.a	h.a	PROPN
admet-2088	816	23	.	.	PROPN
admet-2088	816	24	alhadlaq	alhadlaq	PROPN
admet-2088	816	25	.	.	PUNCT
admet-2088	816	26	induction	induction	NOUN
admet-2088	816	27	of	of	ADP
admet-2088	816	28	oxidative	oxidative	ADJ
admet-2088	816	29	stress	stress	NOUN
admet-2088	816	30	,	,	PUNCT
admet-2088	816	31	dna	dna	NOUN
admet-2088	816	32	damage	damage	NOUN
admet-2088	816	33	,	,	PUNCT
admet-2088	816	34	and	and	CCONJ
admet-2088	816	35	apoptosis	apoptosis	NOUN
admet-2088	816	36	in	in	ADP
admet-2088	816	37	a	a	DET
admet-2088	816	38	malignant	malignant	ADJ
admet-2088	816	39	human	human	ADJ
admet-2088	816	40	skin	skin	NOUN
admet-2088	816	41	melanoma	melanoma	NOUN
admet-2088	816	42	cell	cell	NOUN
admet-2088	816	43	line	line	NOUN
admet-2088	816	44	after	after	ADP
admet-2088	816	45	exposure	exposure	NOUN
admet-2088	816	46	to	to	ADP
admet-2088	816	47	zinc	zinc	NOUN
admet-2088	816	48	oxide	oxide	NOUN
admet-2088	816	49	nanoparticles	nanoparticle	NOUN
admet-2088	816	50	.	.	PUNCT
admet-2088	817	1	international	international	ADJ
admet-2088	817	2	journal	journal	NOUN
admet-2088	817	3	of	of	ADP
admet-2088	817	4	nanomedicine	nanomedicine	ADJ
admet-2088	817	5	8	8	NUM
admet-2088	817	6	(	(	PUNCT
admet-2088	817	7	2013	2013	NUM
admet-2088	817	8	)	)	PUNCT
admet-2088	817	9	983	983	NUM
admet-2088	817	10	.	.	PUNCT
admet-2088	818	1	https://doi.org/10.2147/ijn.s42028	https://doi.org/10.2147/ijn.s42028	NOUN
admet-2088	818	2	.	.	PUNCT
admet-2088	819	1	[	[	X
admet-2088	819	2	28	28	NUM
admet-2088	819	3	]	]	X
admet-2088	819	4	m.	m.	NOUN
admet-2088	819	5	rizzi	rizzi	PROPN
admet-2088	819	6	,	,	PUNCT
admet-2088	819	7	s.	s.	PROPN
admet-2088	819	8	tonello	tonello	PROPN
admet-2088	819	9	,	,	PUNCT
admet-2088	819	10	b.m	b.m	PROPN
admet-2088	819	11	.	.	PROPN
admet-2088	819	12	esteva˜o	esteva˜o	PROPN
admet-2088	819	13	,	,	PUNCT
admet-2088	819	14	e.	e.	PROPN
admet-2088	819	15	gianotti	gianotti	PROPN
admet-2088	819	16	,	,	PUNCT
admet-2088	819	17	l.	l.	PROPN
admet-2088	819	18	marchese	marchese	PROPN
admet-2088	819	19	,	,	PUNCT
admet-2088	819	20	f.	f.	PROPN
admet-2088	819	21	reno	reno	PROPN
admet-2088	819	22	.	.	PUNCT
admet-2088	820	1	verteporfin	verteporfin	PROPN
admet-2088	820	2	based	base	VERB
admet-2088	820	3	silica	silica	NOUN
admet-2088	820	4	nanoparticle	nanoparticle	NOUN
admet-2088	820	5	for	for	ADP
admet-2088	820	6	in	in	ADP
admet-2088	820	7	vitro	vitro	X
admet-2088	820	8	selective	selective	ADJ
admet-2088	820	9	inhibition	inhibition	NOUN
admet-2088	820	10	of	of	ADP
admet-2088	820	11	human	human	ADJ
admet-2088	820	12	highly	highly	ADV
admet-2088	820	13	invasive	invasive	ADJ
admet-2088	820	14	melanoma	melanoma	NOUN
admet-2088	820	15	cell	cell	NOUN
admet-2088	820	16	proliferation	proliferation	NOUN
admet-2088	820	17	.	.	PUNCT
admet-2088	821	1	journal	journal	NOUN
admet-2088	821	2	of	of	ADP
admet-2088	821	3	photochemistry	photochemistry	NOUN
admet-2088	821	4	and	and	CCONJ
admet-2088	821	5	photobiology	photobiology	PROPN
admet-2088	821	6	b.	b.	PROPN
admet-2088	821	7	167	167	NUM
admet-2088	821	8	(	(	PUNCT
admet-2088	821	9	2017	2017	NUM
admet-2088	821	10	)	)	PUNCT
admet-2088	821	11	1	1	NUM
admet-2088	821	12	-	-	SYM
admet-2088	821	13	6	6	NUM
admet-2088	821	14	.	.	PUNCT
admet-2088	822	1	https://doi.org/10.1016/j.jphotobiol.2016.12.021	https://doi.org/10.1016/j.jphotobiol.2016.12.021	NOUN
admet-2088	822	2	.	.	PUNCT
admet-2088	823	1	[	[	X
admet-2088	823	2	29	29	NUM
admet-2088	823	3	]	]	PUNCT
admet-2088	823	4	a.	a.	NOUN
admet-2088	823	5	zielinska	zielinska	PROPN
admet-2088	823	6	,	,	PUNCT
admet-2088	823	7	i.	i.	PROPN
admet-2088	823	8	pereira	pereira	PROPN
admet-2088	823	9	,	,	PUNCT
admet-2088	823	10	s.	s.	PROPN
admet-2088	823	11	antunes	antunes	PROPN
admet-2088	823	12	,	,	PUNCT
admet-2088	823	13	f.j	f.j	PROPN
admet-2088	823	14	.	.	PROPN
admet-2088	823	15	veiga	veiga	PROPN
admet-2088	823	16	,	,	PUNCT
admet-2088	823	17	a.c	a.c	PROPN
admet-2088	823	18	.	.	PROPN
admet-2088	823	19	santos	santos	PROPN
admet-2088	823	20	,	,	PUNCT
admet-2088	823	21	i.	i.	PROPN
admet-2088	823	22	nowak1	nowak1	PROPN
admet-2088	823	23	,	,	PUNCT
admet-2088	823	24	a.m.	a.m.	PROPN
admet-2088	823	25	silva	silva	PROPN
admet-2088	823	26	and	and	CCONJ
admet-2088	823	27	e.b	e.b	PROPN
admet-2088	823	28	.	.	PROPN
admet-2088	823	29	souto	souto	PROPN
admet-2088	823	30	.	.	PUNCT
admet-2088	824	1	mesoporous	mesoporous	ADJ
admet-2088	824	2	silica	silica	NOUN
admet-2088	824	3	nanoparticles	nanoparticle	NOUN
admet-2088	824	4	as	as	ADP
admet-2088	824	5	drug	drug	NOUN
admet-2088	824	6	delivery	delivery	NOUN
admet-2088	824	7	systems	system	NOUN
admet-2088	824	8	against	against	ADP
admet-2088	824	9	melanoma	melanoma	NOUN
admet-2088	824	10	,	,	PUNCT
admet-2088	824	11	in	in	ADP
admet-2088	824	12	design	design	NOUN
admet-2088	824	13	of	of	ADP
admet-2088	824	14	nanostructures	nanostructure	NOUN
admet-2088	824	15	for	for	ADP
admet-2088	824	16	theranostics	theranostic	NOUN
admet-2088	824	17	applications	application	NOUN
admet-2088	824	18	,	,	PUNCT
admet-2088	824	19	a.m.	a.m.	NOUN
admet-2088	824	20	grumezescu	grumezescu	PROPN
admet-2088	824	21	,	,	PUNCT
admet-2088	824	22	(	(	PUNCT
admet-2088	824	23	ed	ed	NOUN
admet-2088	824	24	.	.	PUNCT
admet-2088	824	25	)	)	PUNCT
admet-2088	824	26	.	.	PUNCT
admet-2088	825	1	,	,	PUNCT
admet-2088	825	2	elsevier	elsevier	PROPN
admet-2088	825	3	inc	inc	PROPN
admet-2088	825	4	.	.	PROPN
admet-2088	825	5	,	,	PUNCT
admet-2088	825	6	2018	2018	NUM
admet-2088	825	7	,	,	PUNCT
admet-2088	825	8	p.	p.	NOUN
admet-2088	825	9	437466	437466	NUM
admet-2088	825	10	.	.	PUNCT
admet-2088	826	1	http://dx.doi.org/10.1016/b978-0-12-813669-0.00010-5	http://dx.doi.org/10.1016/b978-0-12-813669-0.00010-5	PROPN
admet-2088	826	2	.	.	PUNCT
admet-2088	827	1	[	[	X
admet-2088	827	2	30	30	NUM
admet-2088	827	3	]	]	PUNCT
admet-2088	827	4	a.	a.	NOUN
admet-2088	827	5	grosu	grosu	PROPN
admet-2088	827	6	-	-	PUNCT
admet-2088	827	7	bularda	bularda	ADJ
admet-2088	827	8	,	,	PUNCT
admet-2088	827	9	l.	l.	PROPN
admet-2088	827	10	lazarescu	lazarescu	PROPN
admet-2088	827	11	,	,	PUNCT
admet-2088	827	12	a.	a.	NOUN
admet-2088	827	13	stoian	stoian	PROPN
admet-2088	827	14	,	,	PUNCT
admet-2088	827	15	i.	i.	PROPN
admet-2088	827	16	lascar	lascar	PROPN
admet-2088	827	17	.	.	PUNCT
admet-2088	828	1	immunology	immunology	NOUN
admet-2088	828	2	and	and	CCONJ
admet-2088	828	3	skin	skin	NOUN
admet-2088	828	4	cancer	cancer	NOUN
admet-2088	828	5	.	.	PUNCT
admet-2088	829	1	archives	archive	NOUN
admet-2088	829	2	of	of	ADP
admet-2088	829	3	clinical	clinical	ADJ
admet-2088	829	4	cases	case	NOUN
admet-2088	829	5	5	5	NUM
admet-2088	829	6	(	(	PUNCT
admet-2088	829	7	2018	2018	NUM
admet-2088	829	8	)	)	PUNCT
admet-2088	829	9	109	109	NUM
admet-2088	829	10	-	-	SYM
admet-2088	829	11	119	119	NUM
admet-2088	829	12	.	.	PUNCT
admet-2088	829	13	https://doi.org/10.22551/2018.20.0503.10137	https://doi.org/10.22551/2018.20.0503.10137	PROPN
admet-2088	829	14	.	.	PUNCT
admet-2088	830	1	[	[	X
admet-2088	830	2	31	31	NUM
admet-2088	830	3	]	]	PUNCT
admet-2088	830	4	a.	a.	NOUN
admet-2088	830	5	katalinic	katalinic	PROPN
admet-2088	830	6	,	,	PUNCT
admet-2088	830	7	u.	u.	PROPN
admet-2088	830	8	kunze	kunze	PROPN
admet-2088	830	9	,	,	PUNCT
admet-2088	830	10	t.	t.	NOUN
admet-2088	830	11	schafer	schafer	PROPN
admet-2088	830	12	.	.	PUNCT
admet-2088	831	1	epidemiology	epidemiology	NOUN
admet-2088	831	2	of	of	ADP
admet-2088	831	3	cutaneous	cutaneous	ADJ
admet-2088	831	4	melanoma	melanoma	NOUN
admet-2088	831	5	and	and	CCONJ
admet-2088	831	6	nonmelanoma	nonmelanoma	ADJ
admet-2088	831	7	skin	skin	NOUN
admet-2088	831	8	cancer	cancer	NOUN
admet-2088	831	9	in	in	ADP
admet-2088	831	10	schleswig	schleswig	PROPN
admet-2088	831	11	-	-	PUNCT
admet-2088	831	12	holstein	holstein	PROPN
admet-2088	831	13	,	,	PUNCT
admet-2088	831	14	germany	germany	PROPN
admet-2088	831	15	:	:	PUNCT
admet-2088	831	16	incidence	incidence	NOUN
admet-2088	831	17	,	,	PUNCT
admet-2088	831	18	clinical	clinical	ADJ
admet-2088	831	19	subtypes	subtype	NOUN
admet-2088	831	20	,	,	PUNCT
admet-2088	831	21	tumour	tumour	NOUN
admet-2088	831	22	stages	stage	NOUN
admet-2088	831	23	and	and	CCONJ
admet-2088	831	24	localization	localization	NOUN
admet-2088	831	25	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	PRON
admet-2088	831	26	https://doi.org/10.1097/cmr.0000000000000604	https://doi.org/10.1097/cmr.0000000000000604	PROPN
admet-2088	831	27	https://www.cancer.gov/about-cancer/treatment/drugs/skin	https://www.cancer.gov/about-cancer/treatment/drugs/skin	PROPN
admet-2088	831	28	https://www.cancer.gov/about-cancer/treatment/drugs/skin	https://www.cancer.gov/about-cancer/treatment/drugs/skin	PROPN
admet-2088	831	29	https://doi.org/10.2105/ajph.2020.305567	https://doi.org/10.2105/ajph.2020.305567	PROPN
admet-2088	831	30	https://doi.org/10.1002/jcp.28181	https://doi.org/10.1002/jcp.28181	PROPN
admet-2088	831	31	https://doi.org/10.1586/era.10.154	https://doi.org/10.1586/era.10.154	VERB
admet-2088	831	32	https://doi.org/10.15541/jim20200091	https://doi.org/10.15541/jim20200091	NOUN
admet-2088	831	33	https://doi.org/10.1016/j.cej.2021.133466	https://doi.org/10.1016/j.cej.2021.133466	PROPN
admet-2088	831	34	https://doi.org/10.1002/anie.201403036	https://doi.org/10.1002/anie.201403036	NOUN
admet-2088	831	35	https://doi.org/10.1016/s1734-1140(12)70901-5	https://doi.org/10.1016/s1734-1140(12)70901-5	NOUN
admet-2088	831	36	https://doi.org/10.1016/j.yexmp.2008.12.004	https://doi.org/10.1016/j.yexmp.2008.12.004	NUM
admet-2088	831	37	https://doi.org/10.1016/j.jddst.2023.104357	https://doi.org/10.1016/j.jddst.2023.104357	PROPN
admet-2088	831	38	https://doi.org/10.3390/nano12040618	https://doi.org/10.3390/nano12040618	PROPN
admet-2088	831	39	https://doi.org/10.2147/ijn.s42028	https://doi.org/10.2147/ijn.s42028	PROPN
admet-2088	831	40	https://doi.org/10.1016/j.jphotobiol.2016.12.021	https://doi.org/10.1016/j.jphotobiol.2016.12.021	NOUN
admet-2088	831	41	http://dx.doi.org/10.1016/b978-0-12-813669-0.00010-5	http://dx.doi.org/10.1016/b978-0-12-813669-0.00010-5	NOUN
admet-2088	831	42	https://doi.org/10.22551/2018.20.0503.10137	https://doi.org/10.22551/2018.20.0503.10137	PROPN
admet-2088	831	43	m.	m.	NOUN
admet-2088	832	1	kulkarni	kulkarni	PROPN
admet-2088	832	2	et	et	PROPN
admet-2088	832	3	al	al	PROPN
admet-2088	832	4	.	.	PROPN
admet-2088	832	5	admet	admet	PROPN
admet-2088	832	6	&	&	CCONJ
admet-2088	832	7	dmpk	dmpk	PROPN
admet-2088	832	8	12(1	12(1	PROPN
admet-2088	832	9	)	)	PUNCT
admet-2088	832	10	(	(	PUNCT
admet-2088	832	11	2024	2024	NUM
admet-2088	832	12	)	)	PUNCT
admet-2088	832	13	107	107	NUM
admet-2088	832	14	-	-	SYM
admet-2088	832	15	150	150	NUM
admet-2088	832	16	138	138	NUM
admet-2088	832	17	(	(	PUNCT
admet-2088	832	18	epidemiology	epidemiology	NOUN
admet-2088	832	19	of	of	ADP
admet-2088	832	20	skin	skin	NOUN
admet-2088	832	21	cancer	cancer	NOUN
admet-2088	832	22	)	)	PUNCT
admet-2088	832	23	.	.	PUNCT
admet-2088	833	1	brazilian	brazilian	ADJ
admet-2088	833	2	journal	journal	PROPN
admet-2088	833	3	of	of	ADP
admet-2088	833	4	dermatology	dermatology	NOUN
admet-2088	833	5	.	.	PUNCT
admet-2088	834	1	149	149	NUM
admet-2088	834	2	(	(	PUNCT
admet-2088	834	3	2003	2003	NUM
admet-2088	834	4	)	)	PUNCT
admet-2088	834	5	1200	1200	NUM
admet-2088	834	6	-	-	SYM
admet-2088	834	7	1206	1206	NUM
admet-2088	834	8	.	.	PUNCT
admet-2088	835	1	https://doi.org/10.1111/j.1365-2133.2003.05554.x	https://doi.org/10.1111/j.1365-2133.2003.05554.x	NOUN
admet-2088	835	2	.	.	PUNCT
admet-2088	836	1	[	[	X
admet-2088	836	2	32	32	NUM
admet-2088	836	3	]	]	X
admet-2088	836	4	h.m	h.m	PROPN
admet-2088	836	5	.	.	PROPN
admet-2088	836	6	gloster	gloster	PROPN
admet-2088	836	7	jr	jr	PROPN
admet-2088	836	8	.	.	PROPN
admet-2088	836	9	,	,	PUNCT
admet-2088	836	10	d.g	d.g	PROPN
admet-2088	836	11	.	.	PROPN
admet-2088	836	12	brodland	brodland	NOUN
admet-2088	836	13	.	.	PUNCT
admet-2088	837	1	the	the	DET
admet-2088	837	2	epidemiology	epidemiology	NOUN
admet-2088	837	3	of	of	ADP
admet-2088	837	4	skin	skin	NOUN
admet-2088	837	5	cancer	cancer	NOUN
admet-2088	837	6	.	.	PUNCT
admet-2088	838	1	dermatologic	dermatologic	ADJ
admet-2088	838	2	surgery	surgery	NOUN
admet-2088	838	3	22	22	NUM
admet-2088	838	4	(	(	PUNCT
admet-2088	838	5	1996	1996	NUM
admet-2088	838	6	)	)	PUNCT
admet-2088	838	7	217	217	NUM
admet-2088	838	8	-	-	SYM
admet-2088	838	9	226	226	NUM
admet-2088	838	10	.	.	PUNCT
admet-2088	839	1	https://doi.org/10.1111/j.1524-4725.1996.tb00312.x	https://doi.org/10.1111/j.1524-4725.1996.tb00312.x	PROPN
admet-2088	839	2	.	.	PUNCT
admet-2088	840	1	[	[	X
admet-2088	840	2	33	33	NUM
admet-2088	840	3	]	]	X
admet-2088	840	4	p.t	p.t	PROPN
admet-2088	840	5	.	.	PROPN
admet-2088	840	6	bradford	bradford	PROPN
admet-2088	840	7	.	.	PUNCT
admet-2088	841	1	skin	skin	NOUN
admet-2088	841	2	cancer	cancer	NOUN
admet-2088	841	3	in	in	ADP
admet-2088	841	4	skin	skin	NOUN
admet-2088	841	5	of	of	ADP
admet-2088	841	6	color	color	NOUN
admet-2088	841	7	.	.	PUNCT
admet-2088	842	1	dermatology	dermatology	NOUN
admet-2088	842	2	nursing	nursing	NOUN
admet-2088	842	3	21	21	NUM
admet-2088	842	4	(	(	PUNCT
admet-2088	842	5	2009	2009	NUM
admet-2088	842	6	)	)	PUNCT
admet-2088	842	7	170	170	NUM
admet-2088	842	8	-	-	SYM
admet-2088	842	9	177	177	NUM
admet-2088	842	10	(	(	PUNCT
admet-2088	842	11	206	206	NUM
admet-2088	842	12	;	;	PUNCT
admet-2088	842	13	quiz	quiz	NOUN
admet-2088	842	14	178	178	NUM
admet-2088	842	15	)	)	PUNCT
admet-2088	842	16	.	.	PUNCT
admet-2088	843	1	https://pubmed.ncbi.nlm.nih.gov/19691228/.	https://pubmed.ncbi.nlm.nih.gov/19691228/.	PUNCT
admet-2088	844	1	[	[	X
admet-2088	844	2	34	34	NUM
admet-2088	844	3	]	]	X
admet-2088	844	4	u.	u.	PROPN
admet-2088	844	5	leiter	leiter	PROPN
admet-2088	844	6	,	,	PUNCT
admet-2088	844	7	u.	u.	PROPN
admet-2088	844	8	keim	keim	PROPN
admet-2088	844	9	,	,	PUNCT
admet-2088	844	10	c.	c.	PROPN
admet-2088	844	11	garbe	garbe	PROPN
admet-2088	844	12	.	.	PUNCT
admet-2088	845	1	epidemiology	epidemiology	NOUN
admet-2088	845	2	of	of	ADP
admet-2088	845	3	skin	skin	NOUN
admet-2088	845	4	cancer	cancer	NOUN
admet-2088	845	5	:	:	PUNCT
admet-2088	845	6	update	update	NOUN
admet-2088	845	7	2019	2019	NUM
admet-2088	845	8	,	,	PUNCT
admet-2088	845	9	in	in	ADP
admet-2088	845	10	sunlight	sunlight	NOUN
admet-2088	845	11	,	,	PUNCT
admet-2088	845	12	vitamin	vitamin	NOUN
admet-2088	845	13	d	d	NOUN
admet-2088	845	14	skin	skin	NOUN
admet-2088	845	15	cancer	cancer	NOUN
admet-2088	845	16	,	,	PUNCT
admet-2088	845	17	reichrath	reichrath	NOUN
admet-2088	845	18	,	,	PUNCT
admet-2088	845	19	j.	j.	PROPN
admet-2088	845	20	(	(	PUNCT
admet-2088	845	21	ed	ed	NOUN
admet-2088	845	22	.	.	PUNCT
admet-2088	845	23	)	)	PUNCT
admet-2088	845	24	.	.	PUNCT
admet-2088	846	1	,	,	PUNCT
admet-2088	846	2	springer	springer	NOUN
admet-2088	846	3	,	,	PUNCT
admet-2088	846	4	cham	cham	PROPN
admet-2088	846	5	.	.	PROPN
admet-2088	846	6	,	,	PUNCT
admet-2088	846	7	2020	2020	NUM
admet-2088	846	8	,	,	PUNCT
admet-2088	846	9	p.	p.	NOUN
admet-2088	846	10	123	123	NUM
admet-2088	846	11	-	-	SYM
admet-2088	846	12	139	139	NUM
admet-2088	846	13	.	.	PUNCT
admet-2088	847	1	https://doi.org/10.1007/978-3-03046227-7-6	https://doi.org/10.1007/978-3-03046227-7-6	VERB
admet-2088	847	2	.	.	PUNCT
admet-2088	848	1	[	[	X
admet-2088	848	2	35	35	NUM
admet-2088	848	3	]	]	X
admet-2088	848	4	m.r	m.r	PROPN
admet-2088	848	5	.	.	PROPN
admet-2088	848	6	hussein	hussein	PROPN
admet-2088	848	7	.	.	PUNCT
admet-2088	849	1	ultraviolet	ultraviolet	ADJ
admet-2088	849	2	radiation	radiation	NOUN
admet-2088	849	3	and	and	CCONJ
admet-2088	849	4	skin	skin	NOUN
admet-2088	849	5	cancer	cancer	NOUN
admet-2088	849	6	:	:	PUNCT
admet-2088	849	7	molecular	molecular	ADJ
admet-2088	849	8	mechanisms	mechanism	NOUN
admet-2088	849	9	.	.	PUNCT
admet-2088	850	1	journal	journal	NOUN
admet-2088	850	2	of	of	ADP
admet-2088	850	3	cutaneous	cutaneous	ADJ
admet-2088	850	4	pathology	pathology	NOUN
admet-2088	850	5	32	32	NUM
admet-2088	850	6	(	(	PUNCT
admet-2088	850	7	2005	2005	NUM
admet-2088	850	8	)	)	PUNCT
admet-2088	850	9	191	191	NUM
admet-2088	850	10	-	-	SYM
admet-2088	850	11	205	205	NUM
admet-2088	850	12	.	.	PUNCT
admet-2088	851	1	https://doi.org/10.1111/j.0303-6987.2005.00281.x	https://doi.org/10.1111/j.0303-6987.2005.00281.x	NOUN
admet-2088	851	2	.	.	PUNCT
admet-2088	852	1	[	[	X
admet-2088	852	2	36	36	NUM
admet-2088	852	3	]	]	X
admet-2088	852	4	a.i.m	a.i.m	PROPN
admet-2088	852	5	.	.	PUNCT
admet-2088	852	6	foundation	foundation	PROPN
admet-2088	852	7	,	,	PUNCT
admet-2088	852	8	about	about	ADP
admet-2088	852	9	melanoma	melanoma	NOUN
admet-2088	852	10	https://www.aimatmelanoma.org/stages-of-melanoma/.	https://www.aimatmelanoma.org/stages-of-melanoma/.	PROPN
admet-2088	852	11	september	september	PROPN
admet-2088	852	12	9	9	NUM
admet-2088	852	13	,	,	PUNCT
admet-2088	852	14	2023	2023	NUM
admet-2088	852	15	[	[	X
admet-2088	852	16	37	37	NUM
admet-2088	852	17	]	]	PUNCT
admet-2088	852	18	m.	m.	NOUN
admet-2088	852	19	rastrelli	rastrelli	PROPN
admet-2088	852	20	,	,	PUNCT
admet-2088	852	21	s.	s.	PROPN
admet-2088	852	22	tropea	tropea	PROPN
admet-2088	852	23	,	,	PUNCT
admet-2088	852	24	c.r	c.r	PROPN
admet-2088	852	25	.	.	PROPN
admet-2088	852	26	rossi	rossi	PROPN
admet-2088	852	27	,	,	PUNCT
admet-2088	852	28	m.	m.	NOUN
admet-2088	852	29	alaibac	alaibac	PROPN
admet-2088	852	30	,	,	PUNCT
admet-2088	852	31	melanoma	melanoma	NOUN
admet-2088	852	32	:	:	PUNCT
admet-2088	852	33	epidemiology	epidemiology	NOUN
admet-2088	852	34	,	,	PUNCT
admet-2088	852	35	risk	risk	NOUN
admet-2088	852	36	factors	factor	NOUN
admet-2088	852	37	,	,	PUNCT
admet-2088	852	38	pathogenesis	pathogenesis	NOUN
admet-2088	852	39	,	,	PUNCT
admet-2088	852	40	diagnosis	diagnosis	NOUN
admet-2088	852	41	and	and	CCONJ
admet-2088	852	42	classification	classification	NOUN
admet-2088	852	43	.	.	PUNCT
admet-2088	853	1	in	in	ADP
admet-2088	853	2	vivo	vivo	NOUN
admet-2088	853	3	28	28	NUM
admet-2088	853	4	(	(	PUNCT
admet-2088	853	5	2014	2014	NUM
admet-2088	853	6	)	)	PUNCT
admet-2088	853	7	1005	1005	NUM
admet-2088	853	8	-	-	SYM
admet-2088	853	9	1011	1011	NUM
admet-2088	853	10	.	.	PUNCT
admet-2088	854	1	https://iv.iiarjournals.org/content/28/6/1005	https://iv.iiarjournals.org/content/28/6/1005	NOUN
admet-2088	854	2	.	.	PUNCT
admet-2088	855	1	[	[	X
admet-2088	855	2	38	38	NUM
admet-2088	855	3	]	]	X
admet-2088	855	4	d.l	d.l	PROPN
admet-2088	855	5	.	.	PROPN
admet-2088	855	6	cummins	cummins	PROPN
admet-2088	855	7	,	,	PUNCT
admet-2088	855	8	j.m	j.m	PROPN
admet-2088	855	9	.	.	PROPN
admet-2088	855	10	cummins	cummins	PROPN
admet-2088	855	11	,	,	PUNCT
admet-2088	855	12	h.	h.	PROPN
admet-2088	855	13	pantle	pantle	PROPN
admet-2088	855	14	,	,	PUNCT
admet-2088	855	15	m.a	m.a	PROPN
admet-2088	855	16	.	.	PROPN
admet-2088	855	17	silverman	silverman	PROPN
admet-2088	855	18	,	,	PUNCT
admet-2088	855	19	a.l	a.l	PROPN
admet-2088	855	20	.	.	PROPN
admet-2088	855	21	leonard	leonard	PROPN
admet-2088	855	22	,	,	PUNCT
admet-2088	855	23	a.	a.	PROPN
admet-2088	855	24	chanmugam	chanmugam	PROPN
admet-2088	855	25	.	.	PUNCT
admet-2088	856	1	cutaneous	cutaneous	ADJ
admet-2088	856	2	malignant	malignant	ADJ
admet-2088	856	3	melanoma	melanoma	NOUN
admet-2088	856	4	.	.	PUNCT
admet-2088	857	1	mayo	mayo	NOUN
admet-2088	857	2	clinic	clinic	NOUN
admet-2088	857	3	proceedings	proceeding	NOUN
admet-2088	857	4	81	81	NUM
admet-2088	857	5	(	(	PUNCT
admet-2088	857	6	2006	2006	NUM
admet-2088	857	7	)	)	PUNCT
admet-2088	857	8	500	500	NUM
admet-2088	857	9	-	-	SYM
admet-2088	857	10	507	507	NUM
admet-2088	857	11	.	.	PUNCT
admet-2088	858	1	https://doi.org/10.4065/81.4.500	https://doi.org/10.4065/81.4.500	NOUN
admet-2088	858	2	.	.	PUNCT
admet-2088	859	1	[	[	X
admet-2088	859	2	39	39	NUM
admet-2088	859	3	]	]	PUNCT
admet-2088	859	4	s.	s.	PROPN
admet-2088	859	5	carr	carr	PROPN
admet-2088	859	6	,	,	PUNCT
admet-2088	859	7	c.	c.	PROPN
admet-2088	859	8	smith	smith	PROPN
admet-2088	859	9	,	,	PUNCT
admet-2088	859	10	j.	j.	PROPN
admet-2088	859	11	wernberg	wernberg	PROPN
admet-2088	859	12	.	.	PUNCT
admet-2088	860	1	epidemiology	epidemiology	NOUN
admet-2088	860	2	and	and	CCONJ
admet-2088	860	3	risk	risk	NOUN
admet-2088	860	4	factors	factor	NOUN
admet-2088	860	5	of	of	ADP
admet-2088	860	6	melanoma	melanoma	NOUN
admet-2088	860	7	.	.	PUNCT
admet-2088	861	1	surgical	surgical	ADJ
admet-2088	861	2	clinics	clinic	NOUN
admet-2088	861	3	100	100	NUM
admet-2088	861	4	(	(	PUNCT
admet-2088	861	5	2020	2020	NUM
admet-2088	861	6	)	)	PUNCT
admet-2088	861	7	1	1	NUM
admet-2088	861	8	-	-	SYM
admet-2088	861	9	12	12	NUM
admet-2088	861	10	,	,	PUNCT
admet-2088	861	11	https://doi.org/10.1016/j.suc.2019.09.005	https://doi.org/10.1016/j.suc.2019.09.005	VERB
admet-2088	861	12	.	.	PUNCT
admet-2088	862	1	[	[	X
admet-2088	862	2	40	40	NUM
admet-2088	862	3	]	]	PUNCT
admet-2088	862	4	j.	j.	PROPN
admet-2088	862	5	li	li	PROPN
admet-2088	862	6	,	,	PUNCT
admet-2088	862	7	y.	y.	PROPN
admet-2088	862	8	zhang	zhang	PROPN
admet-2088	862	9	,	,	PUNCT
admet-2088	862	10	j.	j.	PROPN
admet-2088	862	11	tao	tao	PROPN
admet-2088	862	12	.	.	PUNCT
admet-2088	863	1	targeted	target	VERB
admet-2088	863	2	nanoparticles	nanoparticle	NOUN
admet-2088	863	3	for	for	ADP
admet-2088	863	4	drug	drug	NOUN
admet-2088	863	5	delivery	delivery	NOUN
admet-2088	863	6	to	to	PART
admet-2088	863	7	melanoma	melanoma	VERB
admet-2088	863	8	:	:	PUNCT
admet-2088	863	9	from	from	ADP
admet-2088	863	10	bench	bench	NOUN
admet-2088	863	11	to	to	ADP
admet-2088	863	12	bedside	bedside	NOUN
admet-2088	863	13	.	.	PUNCT
admet-2088	864	1	in	in	ADP
admet-2088	864	2	nanoscience	nanoscience	NOUN
admet-2088	864	3	in	in	ADP
admet-2088	864	4	dermatology	dermatology	NOUN
admet-2088	864	5	,	,	PUNCT
admet-2088	864	6	m.r	m.r	PROPN
admet-2088	864	7	.	.	PROPN
admet-2088	864	8	hamblin	hamblin	PROPN
admet-2088	864	9	,	,	PUNCT
admet-2088	864	10	p.	p.	NOUN
admet-2088	864	11	avci	avci	PROPN
admet-2088	864	12	,	,	PUNCT
admet-2088	864	13	t.w	t.w	PROPN
admet-2088	864	14	.	.	PROPN
admet-2088	864	15	prow	prow	PROPN
admet-2088	864	16	,	,	PUNCT
admet-2088	864	17	(	(	PUNCT
admet-2088	864	18	eds	ed	NOUN
admet-2088	864	19	.	.	PUNCT
admet-2088	864	20	)	)	PUNCT
admet-2088	864	21	.	.	PUNCT
admet-2088	865	1	,	,	PUNCT
admet-2088	865	2	elsevier	elsevier	PROPN
admet-2088	865	3	inc	inc	PROPN
admet-2088	865	4	.	.	PROPN
admet-2088	865	5	,	,	PUNCT
admet-2088	865	6	p.	p.	NOUN
admet-2088	865	7	203	203	NUM
admet-2088	865	8	-	-	SYM
admet-2088	865	9	215	215	NUM
admet-2088	865	10	.	.	PUNCT
admet-2088	866	1	http://dx.doi.org/10.1016/b978-0-12-802926-8.00016-1	http://dx.doi.org/10.1016/b978-0-12-802926-8.00016-1	ADV
admet-2088	866	2	.	.	PUNCT
admet-2088	867	1	[	[	X
admet-2088	867	2	41	41	NUM
admet-2088	867	3	]	]	X
admet-2088	867	4	e.	e.	PROPN
admet-2088	867	5	hodis	hodis	PROPN
admet-2088	867	6	,	,	PUNCT
admet-2088	867	7	i.r	i.r	PROPN
admet-2088	867	8	.	.	PROPN
admet-2088	867	9	watson	watson	PROPN
admet-2088	867	10	,	,	PUNCT
admet-2088	867	11	g.v	g.v	PROPN
admet-2088	867	12	.	.	PROPN
admet-2088	867	13	kryukov	kryukov	PROPN
admet-2088	867	14	,	,	PUNCT
admet-2088	867	15	s.t	s.t	PROPN
admet-2088	867	16	.	.	PROPN
admet-2088	867	17	arold	arold	PROPN
admet-2088	867	18	,	,	PUNCT
admet-2088	867	19	m.	m.	NOUN
admet-2088	867	20	imielinski	imielinski	PROPN
admet-2088	867	21	,	,	PUNCT
admet-2088	867	22	j.p	j.p	PROPN
admet-2088	867	23	.	.	PROPN
admet-2088	867	24	theurillat	theurillat	NOUN
admet-2088	867	25	,	,	PUNCT
admet-2088	867	26	e.	e.	PROPN
admet-2088	867	27	nickerson	nickerson	PROPN
admet-2088	867	28	,	,	PUNCT
admet-2088	867	29	d.	d.	PROPN
admet-2088	867	30	auclair	auclair	PROPN
admet-2088	867	31	,	,	PUNCT
admet-2088	867	32	l.	l.	PROPN
admet-2088	867	33	li	li	PROPN
admet-2088	867	34	,	,	PUNCT
admet-2088	867	35	c.	c.	PROPN
admet-2088	867	36	place	place	PROPN
admet-2088	867	37	,	,	PUNCT
admet-2088	867	38	d.	d.	PROPN
admet-2088	867	39	dicara	dicara	PROPN
admet-2088	867	40	,	,	PUNCT
admet-2088	867	41	a.h	a.h	PROPN
admet-2088	867	42	.	.	PROPN
admet-2088	867	43	ramos	ramos	PROPN
admet-2088	867	44	,	,	PUNCT
admet-2088	867	45	m.s	m.s	PROPN
admet-2088	867	46	.	.	PROPN
admet-2088	867	47	lawrence	lawrence	PROPN
admet-2088	867	48	,	,	PUNCT
admet-2088	867	49	k.	k.	PROPN
admet-2088	867	50	cibulskis	cibulskis	PROPN
admet-2088	867	51	,	,	PUNCT
admet-2088	867	52	a.	a.	PROPN
admet-2088	867	53	sivachenko	sivachenko	PROPN
admet-2088	867	54	,	,	PUNCT
admet-2088	867	55	d.	d.	PROPN
admet-2088	867	56	voet	voet	PROPN
admet-2088	867	57	,	,	PUNCT
admet-2088	867	58	g.	g.	PROPN
admet-2088	867	59	saksena	saksena	PROPN
admet-2088	867	60	,	,	PUNCT
admet-2088	867	61	n.	n.	PROPN
admet-2088	867	62	stransky	stransky	PROPN
admet-2088	867	63	,	,	PUNCT
admet-2088	867	64	r.c	r.c	PROPN
admet-2088	867	65	.	.	PROPN
admet-2088	867	66	onofrio	onofrio	PROPN
admet-2088	867	67	,	,	PUNCT
admet-2088	867	68	w.	w.	PROPN
admet-2088	867	69	winckler	winckler	PROPN
admet-2088	867	70	,	,	PUNCT
admet-2088	867	71	k.	k.	PROPN
admet-2088	867	72	ardlie	ardlie	PROPN
admet-2088	867	73	,	,	PUNCT
admet-2088	867	74	n.	n.	PROPN
admet-2088	867	75	wagle	wagle	PROPN
admet-2088	867	76	,	,	PUNCT
admet-2088	867	77	j.	j.	PROPN
admet-2088	867	78	wargo	wargo	PROPN
admet-2088	867	79	,	,	PUNCT
admet-2088	867	80	k.	k.	PROPN
admet-2088	867	81	chong	chong	PROPN
admet-2088	867	82	,	,	PUNCT
admet-2088	867	83	d.l	d.l	PROPN
admet-2088	867	84	.	.	PROPN
admet-2088	867	85	morton	morton	PROPN
admet-2088	867	86	,	,	PUNCT
admet-2088	867	87	k.	k.	PROPN
admet-2088	867	88	stemke	stemke	PROPN
admet-2088	867	89	-	-	PUNCT
admet-2088	867	90	hale	hale	PROPN
admet-2088	867	91	,	,	PUNCT
admet-2088	867	92	g.	g.	PROPN
admet-2088	867	93	chen	chen	PROPN
admet-2088	867	94	,	,	PUNCT
admet-2088	867	95	m.	m.	NOUN
admet-2088	867	96	noble	noble	ADJ
admet-2088	867	97	,	,	PUNCT
admet-2088	867	98	m.	m.	NOUN
admet-2088	867	99	meyerson	meyerson	PROPN
admet-2088	867	100	,	,	PUNCT
admet-2088	867	101	j.e	j.e	PROPN
admet-2088	867	102	.	.	PROPN
admet-2088	867	103	ladbury	ladbury	PROPN
admet-2088	867	104	,	,	PUNCT
admet-2088	867	105	m.a	m.a	PROPN
admet-2088	867	106	.	.	PROPN
admet-2088	867	107	davies	davy	NOUN
admet-2088	867	108	,	,	PUNCT
admet-2088	867	109	j.e	j.e	PROPN
admet-2088	867	110	.	.	PROPN
admet-2088	867	111	gershenwald	gershenwald	PROPN
admet-2088	867	112	,	,	PUNCT
admet-2088	867	113	s.n	s.n	PROPN
admet-2088	867	114	.	.	PROPN
admet-2088	867	115	wagner	wagner	PROPN
admet-2088	867	116	,	,	PUNCT
admet-2088	867	117	d.s.b	d.s.b	NOUN
admet-2088	867	118	.	.	PUNCT
admet-2088	868	1	hoon	hoon	PROPN
admet-2088	868	2	,	,	PUNCT
admet-2088	868	3	d.	d.	PROPN
admet-2088	868	4	schadendorf	schadendorf	PROPN
admet-2088	868	5	,	,	PUNCT
admet-2088	868	6	e.s	e.s	PROPN
admet-2088	868	7	.	.	PROPN
admet-2088	868	8	lander	lander	PROPN
admet-2088	868	9	,	,	PUNCT
admet-2088	868	10	s.b	s.b	PROPN
admet-2088	868	11	.	.	PROPN
admet-2088	868	12	gabriel	gabriel	PROPN
admet-2088	868	13	,	,	PUNCT
admet-2088	868	14	g.	g.	PROPN
admet-2088	868	15	getz	getz	PROPN
admet-2088	868	16	,	,	PUNCT
admet-2088	868	17	l.a	l.a	PROPN
admet-2088	868	18	.	.	PROPN
admet-2088	868	19	garraway	garraway	PROPN
admet-2088	868	20	,	,	PUNCT
admet-2088	868	21	l.	l.	PROPN
admet-2088	868	22	chin	chin	PROPN
admet-2088	868	23	.	.	PUNCT
admet-2088	869	1	a	a	DET
admet-2088	869	2	landscape	landscape	NOUN
admet-2088	869	3	of	of	ADP
admet-2088	869	4	driver	driver	NOUN
admet-2088	869	5	mutations	mutation	NOUN
admet-2088	869	6	in	in	ADP
admet-2088	869	7	melanoma	melanoma	NOUN
admet-2088	869	8	.	.	PUNCT
admet-2088	870	1	cell	cell	NOUN
admet-2088	870	2	150	150	NUM
admet-2088	870	3	(	(	PUNCT
admet-2088	870	4	2012	2012	NUM
admet-2088	870	5	)	)	PUNCT
admet-2088	870	6	251	251	NUM
admet-2088	870	7	-	-	SYM
admet-2088	870	8	163	163	NUM
admet-2088	870	9	.	.	PUNCT
admet-2088	871	1	https://doi.org/10.1016/j.cell.2012.06.024	https://doi.org/10.1016/j.cell.2012.06.024	VERB
admet-2088	871	2	.	.	PUNCT
admet-2088	872	1	[	[	X
admet-2088	872	2	42	42	NUM
admet-2088	872	3	]	]	PUNCT
admet-2088	872	4	p.	p.	NOUN
admet-2088	872	5	vukovi´c	vukovi´c	PROPN
admet-2088	872	6	,	,	PUNCT
admet-2088	872	7	l.	l.	PROPN
admet-2088	872	8	lugovi´c	lugovi´c	PROPN
admet-2088	872	9	-	-	PUNCT
admet-2088	872	10	mihi´c	mihi´c	NOUN
admet-2088	872	11	,	,	PUNCT
admet-2088	872	12	d.	d.	PROPN
admet-2088	872	13	cesic	cesic	PROPN
admet-2088	872	14	,	,	PUNCT
admet-2088	872	15	g.	g.	PROPN
admet-2088	872	16	novak	novak	PROPN
admet-2088	872	17	-	-	PUNCT
admet-2088	872	18	bili´c	bili´c	PROPN
admet-2088	872	19	,	,	PUNCT
admet-2088	872	20	m.	m.	NOUN
admet-2088	872	21	situm	situm	PROPN
admet-2088	872	22	,	,	PUNCT
admet-2088	872	23	s.	s.	PROPN
admet-2088	872	24	spoljar	spoljar	PROPN
admet-2088	872	25	,	,	PUNCT
admet-2088	872	26	melanoma	melanoma	PROPN
admet-2088	872	27	development	development	NOUN
admet-2088	872	28	:	:	PUNCT
admet-2088	872	29	current	current	ADJ
admet-2088	872	30	knowledge	knowledge	NOUN
admet-2088	872	31	on	on	ADP
admet-2088	872	32	melanoma	melanoma	NOUN
admet-2088	872	33	pathogenesis	pathogenesis	NOUN
admet-2088	872	34	.	.	PUNCT
admet-2088	873	1	acta	acta	PROPN
admet-2088	873	2	dermatovenerologica	dermatovenerologica	PROPN
admet-2088	873	3	croatica	croatica	PROPN
admet-2088	873	4	28	28	NUM
admet-2088	873	5	(	(	PUNCT
admet-2088	873	6	2020	2020	NUM
admet-2088	873	7	)	)	PUNCT
admet-2088	873	8	163	163	NUM
admet-2088	873	9	-	-	SYM
admet-2088	873	10	163	163	NUM
admet-2088	873	11	.	.	PUNCT
admet-2088	874	1	https://hrcak.srce.hr/225444	https://hrcak.srce.hr/225444	NOUN
admet-2088	874	2	.	.	PUNCT
admet-2088	875	1	[	[	X
admet-2088	875	2	43	43	NUM
admet-2088	875	3	]	]	X
admet-2088	875	4	v.m	v.m	PROPN
admet-2088	875	5	.	.	PROPN
admet-2088	875	6	prajapat	prajapat	PROPN
admet-2088	875	7	,	,	PUNCT
admet-2088	875	8	s.	s.	PROPN
admet-2088	875	9	mahajan	mahajan	PROPN
admet-2088	875	10	,	,	PUNCT
admet-2088	875	11	p.g	p.g	PROPN
admet-2088	875	12	.	.	PROPN
admet-2088	875	13	paul	paul	PROPN
admet-2088	875	14	,	,	PUNCT
admet-2088	875	15	m.	m.	NOUN
admet-2088	875	16	aalhate	aalhate	NOUN
admet-2088	875	17	,	,	PUNCT
admet-2088	875	18	a.	a.	NOUN
admet-2088	875	19	mehandole	mehandole	NOUN
admet-2088	875	20	,	,	PUNCT
admet-2088	875	21	j.	j.	PROPN
admet-2088	875	22	madan	madan	PROPN
admet-2088	875	23	,	,	PUNCT
admet-2088	875	24	k.	k.	PROPN
admet-2088	875	25	dua	dua	PROPN
admet-2088	875	26	,	,	PUNCT
admet-2088	875	27	d.k	d.k	PROPN
admet-2088	875	28	.	.	PROPN
admet-2088	875	29	chellappan	chellappan	PROPN
admet-2088	875	30	,	,	PUNCT
admet-2088	875	31	s.k	s.k	PROPN
admet-2088	875	32	.	.	PROPN
admet-2088	875	33	singh	singh	PROPN
admet-2088	875	34	,	,	PUNCT
admet-2088	875	35	p.k	p.k	PROPN
admet-2088	875	36	.	.	PROPN
admet-2088	876	1	singh	singh	PROPN
admet-2088	876	2	.	.	PUNCT
admet-2088	877	1	nanomedicine	nanomedicine	PROPN
admet-2088	877	2	:	:	PUNCT
admet-2088	877	3	a	a	DET
admet-2088	877	4	pragmatic	pragmatic	ADJ
admet-2088	877	5	approach	approach	NOUN
admet-2088	877	6	for	for	ADP
admet-2088	877	7	tackling	tackle	VERB
admet-2088	877	8	melanoma	melanoma	NOUN
admet-2088	877	9	skin	skin	NOUN
admet-2088	877	10	cancer	cancer	NOUN
admet-2088	877	11	.	.	PUNCT
admet-2088	878	1	journal	journal	PROPN
admet-2088	878	2	of	of	ADP
admet-2088	878	3	drug	drug	NOUN
admet-2088	878	4	delivery	delivery	NOUN
admet-2088	878	5	science	science	NOUN
admet-2088	878	6	and	and	CCONJ
admet-2088	878	7	technology	technology	NOUN
admet-2088	878	8	83	83	NUM
admet-2088	878	9	(	(	PUNCT
admet-2088	878	10	2023	2023	NUM
admet-2088	878	11	)	)	PUNCT
admet-2088	878	12	104394	104394	NUM
admet-2088	878	13	.	.	PUNCT
admet-2088	879	1	https://doi.org/10.1016/j.jddst.2023.104394	https://doi.org/10.1016/j.jddst.2023.104394	NOUN
admet-2088	879	2	.	.	PUNCT
admet-2088	880	1	[	[	X
admet-2088	880	2	44	44	NUM
admet-2088	880	3	]	]	PUNCT
admet-2088	880	4	c.	c.	PROPN
admet-2088	880	5	blank	blank	PROPN
admet-2088	880	6	,	,	PUNCT
admet-2088	880	7	i.	i.	PROPN
admet-2088	880	8	brown	brown	PROPN
admet-2088	880	9	,	,	PUNCT
admet-2088	880	10	a.c	a.c	PROPN
admet-2088	880	11	.	.	PROPN
admet-2088	880	12	peterson	peterson	PROPN
admet-2088	880	13	,	,	PUNCT
admet-2088	880	14	m.	m.	NOUN
admet-2088	880	15	spiotto	spiotto	PROPN
admet-2088	880	16	,	,	PUNCT
admet-2088	880	17	y.	y.	PROPN
admet-2088	880	18	iwai	iwai	PROPN
admet-2088	880	19	,	,	PUNCT
admet-2088	880	20	t.	t.	PROPN
admet-2088	880	21	honjo	honjo	PROPN
admet-2088	880	22	,	,	PUNCT
admet-2088	880	23	t.f	t.f	PROPN
admet-2088	880	24	.	.	PROPN
admet-2088	880	25	gajewski	gajewski	PROPN
admet-2088	880	26	.	.	PUNCT
admet-2088	881	1	pd	pd	PROPN
admet-2088	881	2	-	-	PUNCT
admet-2088	881	3	l1	l1	PROPN
admet-2088	881	4	/	/	SYM
admet-2088	881	5	b7h-1	b7h-1	PROPN
admet-2088	881	6	inhibits	inhibit	VERB
admet-2088	881	7	the	the	DET
admet-2088	881	8	effector	effector	NOUN
admet-2088	881	9	phase	phase	NOUN
admet-2088	881	10	of	of	ADP
admet-2088	881	11	tumor	tumor	NOUN
admet-2088	881	12	rejection	rejection	NOUN
admet-2088	881	13	by	by	ADP
admet-2088	881	14	t	t	NOUN
admet-2088	881	15	cell	cell	NOUN
admet-2088	881	16	receptor	receptor	NOUN
admet-2088	881	17	(	(	PUNCT
admet-2088	881	18	tcr	tcr	PROPN
admet-2088	881	19	)	)	PUNCT
admet-2088	881	20	transgenic	transgenic	NOUN
admet-2088	881	21	cd8þ	cd8þ	PROPN
admet-2088	881	22	t	t	NOUN
admet-2088	881	23	cells	cell	NOUN
admet-2088	881	24	.	.	PUNCT
admet-2088	882	1	cancer	cancer	NOUN
admet-2088	882	2	research	research	NOUN
admet-2088	882	3	64	64	NUM
admet-2088	882	4	(	(	PUNCT
admet-2088	882	5	2004	2004	NUM
admet-2088	882	6	)	)	PUNCT
admet-2088	882	7	1140	1140	NUM
admet-2088	882	8	-	-	SYM
admet-2088	882	9	1145	1145	NUM
admet-2088	882	10	.	.	PUNCT
admet-2088	883	1	https://doi.org/10.1158/0008-5472.can-03-3259	https://doi.org/10.1158/0008-5472.can-03-3259	X
admet-2088	883	2	.	.	PUNCT
admet-2088	884	1	[	[	X
admet-2088	884	2	45	45	NUM
admet-2088	884	3	]	]	PUNCT
admet-2088	884	4	mellman	mellman	NOUN
admet-2088	884	5	,	,	PUNCT
admet-2088	884	6	g.	g.	PROPN
admet-2088	884	7	coukos	coukos	PROPN
admet-2088	884	8	,	,	PUNCT
admet-2088	884	9	g.	g.	PROPN
admet-2088	884	10	dranoff	dranoff	PROPN
admet-2088	884	11	.	.	PUNCT
admet-2088	885	1	cancer	cancer	NOUN
admet-2088	885	2	immunotherapy	immunotherapy	NOUN
admet-2088	885	3	comes	come	VERB
admet-2088	885	4	of	of	ADP
admet-2088	885	5	age	age	NOUN
admet-2088	885	6	.	.	PUNCT
admet-2088	886	1	nature	nature	NOUN
admet-2088	886	2	480	480	NUM
admet-2088	886	3	(	(	PUNCT
admet-2088	886	4	2011	2011	NUM
admet-2088	886	5	)	)	PUNCT
admet-2088	886	6	(	(	PUNCT
admet-2088	886	7	7378	7378	NUM
admet-2088	886	8	)	)	PUNCT
admet-2088	886	9	480	480	NUM
admet-2088	886	10	-	-	SYM
admet-2088	886	11	489	489	NUM
admet-2088	886	12	.	.	PUNCT
admet-2088	887	1	https://doi.org/10.1038/nature10673	https://doi.org/10.1038/nature10673	PROPN
admet-2088	887	2	.	.	PUNCT
admet-2088	888	1	[	[	X
admet-2088	888	2	46	46	NUM
admet-2088	888	3	]	]	X
admet-2088	888	4	c.	c.	PROPN
admet-2088	888	5	garbe	garbe	PROPN
admet-2088	888	6	,	,	PUNCT
admet-2088	888	7	t.k	t.k	PROPN
admet-2088	888	8	.	.	PROPN
admet-2088	888	9	eigentler	eigentler	NOUN
admet-2088	888	10	,	,	PUNCT
admet-2088	888	11	u.	u.	PROPN
admet-2088	888	12	keilholz	keilholz	PROPN
admet-2088	888	13	,	,	PUNCT
admet-2088	888	14	a.	a.	NOUN
admet-2088	888	15	hauschild	hauschild	PROPN
admet-2088	888	16	,	,	PUNCT
admet-2088	888	17	j.m	j.m	PROPN
admet-2088	888	18	.	.	PROPN
admet-2088	888	19	kirkwood	kirkwood	PROPN
admet-2088	888	20	.	.	PUNCT
admet-2088	889	1	systematic	systematic	ADJ
admet-2088	889	2	review	review	NOUN
admet-2088	889	3	of	of	ADP
admet-2088	889	4	medical	medical	ADJ
admet-2088	889	5	treatment	treatment	NOUN
admet-2088	889	6	in	in	ADP
admet-2088	889	7	melanoma	melanoma	NOUN
admet-2088	889	8	:	:	PUNCT
admet-2088	889	9	current	current	ADJ
admet-2088	889	10	status	status	NOUN
admet-2088	889	11	and	and	CCONJ
admet-2088	889	12	future	future	ADJ
admet-2088	889	13	prospects	prospect	NOUN
admet-2088	889	14	.	.	PUNCT
admet-2088	890	1	oncologist	oncologist	NOUN
admet-2088	890	2	16	16	NUM
admet-2088	890	3	(	(	PUNCT
admet-2088	890	4	2011	2011	NUM
admet-2088	890	5	)	)	PUNCT
admet-2088	890	6	5	5	NUM
admet-2088	890	7	-	-	SYM
admet-2088	890	8	24	24	NUM
admet-2088	890	9	.	.	PUNCT
admet-2088	891	1	https://doi.org/10.1634/theoncologist.2010-0190	https://doi.org/10.1634/theoncologist.2010-0190	PROPN
admet-2088	891	2	.	.	PUNCT
admet-2088	892	1	[	[	X
admet-2088	892	2	47	47	NUM
admet-2088	892	3	]	]	PUNCT
admet-2088	892	4	p.	p.	PROPN
admet-2088	892	5	das	das	PROPN
admet-2088	892	6	,	,	PUNCT
admet-2088	892	7	n.	n.	PROPN
admet-2088	892	8	deshmukh	deshmukh	PROPN
admet-2088	892	9	,	,	PUNCT
admet-2088	892	10	n.	n.	PROPN
admet-2088	892	11	badore	badore	PROPN
admet-2088	892	12	,	,	PUNCT
admet-2088	892	13	c.	c.	PROPN
admet-2088	892	14	ghulaxe	ghulaxe	PROPN
admet-2088	892	15	,	,	PUNCT
admet-2088	892	16	p.	p.	PROPN
admet-2088	892	17	patel	patel	PROPN
admet-2088	892	18	.	.	PUNCT
admet-2088	893	1	a	a	DET
admet-2088	893	2	review	review	NOUN
admet-2088	893	3	article	article	NOUN
admet-2088	893	4	on	on	ADP
admet-2088	893	5	melanoma	melanoma	PROPN
admet-2088	893	6	.	.	PUNCT
admet-2088	894	1	journal	journal	PROPN
admet-2088	894	2	of	of	ADP
admet-2088	894	3	pharmaceutical	pharmaceutical	NOUN
admet-2088	894	4	sciences	science	NOUN
admet-2088	894	5	and	and	CCONJ
admet-2088	894	6	research	research	NOUN
admet-2088	894	7	8	8	NUM
admet-2088	894	8	(	(	PUNCT
admet-2088	894	9	2016	2016	NUM
admet-2088	894	10	)	)	PUNCT
admet-2088	894	11	112	112	NUM
admet-2088	894	12	-	-	SYM
admet-2088	894	13	117	117	NUM
admet-2088	894	14	.	.	PUNCT
admet-2088	895	1	https://www.jpsr.pharmainfo.in/documents/volumes/vol8issue02/jpsr08021610	https://www.jpsr.pharmainfo.in/documents/volumes/vol8issue02/jpsr08021610	X
admet-2088	895	2	.	.	PUNCT
admet-2088	896	1	[	[	X
admet-2088	896	2	48	48	NUM
admet-2088	896	3	]	]	SYM
admet-2088	896	4	c.m	c.m	PROPN
admet-2088	896	5	.	.	PROPN
admet-2088	896	6	balch	balch	PROPN
admet-2088	896	7	,	,	PUNCT
admet-2088	896	8	j.e	j.e	PROPN
admet-2088	896	9	.	.	PROPN
admet-2088	896	10	gershenwald	gershenwald	PROPN
admet-2088	896	11	,	,	PUNCT
admet-2088	896	12	s.j	s.j	PROPN
admet-2088	896	13	.	.	PROPN
admet-2088	896	14	soong	soong	PROPN
admet-2088	896	15	,	,	PUNCT
admet-2088	896	16	j.f	j.f	PROPN
admet-2088	896	17	.	.	PROPN
admet-2088	896	18	thompson	thompson	PROPN
admet-2088	896	19	,	,	PUNCT
admet-2088	896	20	m.b	m.b	PROPN
admet-2088	896	21	.	.	PROPN
admet-2088	896	22	atkins	atkins	PROPN
admet-2088	896	23	,	,	PUNCT
admet-2088	896	24	d.r	d.r	PROPN
admet-2088	896	25	.	.	PROPN
admet-2088	896	26	byrd	byrd	PROPN
admet-2088	896	27	,	,	PUNCT
admet-2088	896	28	a.c	a.c	PROPN
admet-2088	896	29	.	.	PROPN
admet-2088	896	30	buzaid	buzaid	PROPN
admet-2088	896	31	,	,	PUNCT
admet-2088	896	32	a.j	a.j	PROPN
admet-2088	896	33	.	.	PROPN
admet-2088	896	34	cochran	cochran	PROPN
admet-2088	896	35	,	,	PUNCT
admet-2088	896	36	d.g	d.g	PROPN
admet-2088	896	37	.	.	PROPN
admet-2088	896	38	coit	coit	PROPN
admet-2088	896	39	,	,	PUNCT
admet-2088	896	40	s.	s.	PROPN
admet-2088	896	41	ding	ding	PROPN
admet-2088	896	42	,	,	PUNCT
admet-2088	896	43	a.m.	a.m.	NOUN
admet-2088	896	44	eggermont	eggermont	PROPN
admet-2088	896	45	,	,	PUNCT
admet-2088	896	46	k.t	k.t	PROPN
admet-2088	896	47	.	.	PROPN
admet-2088	896	48	flaherty	flaherty	PROPN
admet-2088	896	49	,	,	PUNCT
admet-2088	896	50	p.a	p.a	PROPN
admet-2088	896	51	.	.	PROPN
admet-2088	896	52	gimotty	gimotty	PROPN
admet-2088	896	53	,	,	PUNCT
admet-2088	896	54	j.m	j.m	PROPN
admet-2088	896	55	.	.	PROPN
admet-2088	896	56	kirkwood	kirkwood	PROPN
admet-2088	896	57	,	,	PUNCT
admet-2088	896	58	k.m	k.m	PROPN
admet-2088	896	59	.	.	PROPN
admet-2088	896	60	mcmasters	mcmasters	PROPN
admet-2088	896	61	,	,	PUNCT
admet-2088	896	62	m.c	m.c	PROPN
admet-2088	896	63	.	.	PROPN
admet-2088	896	64	mihm	mihm	PROPN
admet-2088	896	65	jr	jr	PROPN
admet-2088	896	66	,	,	PUNCT
admet-2088	896	67	d.l	d.l	PROPN
admet-2088	896	68	.	.	PROPN
admet-2088	896	69	morton	morton	PROPN
admet-2088	896	70	,	,	PUNCT
admet-2088	896	71	m.i	m.i	PROPN
admet-2088	896	72	.	.	PROPN
admet-2088	896	73	ross	ross	PROPN
admet-2088	896	74	,	,	PUNCT
admet-2088	896	75	a.j	a.j	PROPN
admet-2088	896	76	.	.	PROPN
admet-2088	896	77	sober	sober	PROPN
admet-2088	896	78	,	,	PUNCT
admet-2088	896	79	v.k	v.k	PROPN
admet-2088	896	80	.	.	PROPN
admet-2088	896	81	sondak	sondak	PROPN
admet-2088	896	82	.	.	PUNCT
admet-2088	897	1	final	final	ADJ
admet-2088	897	2	version	version	NOUN
admet-2088	897	3	of	of	ADP
admet-2088	897	4	2009	2009	NUM
admet-2088	897	5	https://doi.org/10.1111/j.1365-2133.2003.05554.x	https://doi.org/10.1111/j.1365-2133.2003.05554.x	NOUN
admet-2088	897	6	https://doi.org/10.1111/j.1524-4725.1996.tb00312.x	https://doi.org/10.1111/j.1524-4725.1996.tb00312.x	PROPN
admet-2088	897	7	https://pubmed.ncbi.nlm.nih.gov/19691228/	https://pubmed.ncbi.nlm.nih.gov/19691228/	PROPN
admet-2088	897	8	https://doi.org/10.1007/978-3-030-46227-7-6	https://doi.org/10.1007/978-3-030-46227-7-6	PROPN
admet-2088	897	9	https://doi.org/10.1007/978-3-030-46227-7-6	https://doi.org/10.1007/978-3-030-46227-7-6	VERB
admet-2088	897	10	https://doi.org/10.1111/j.0303-6987.2005.00281.x	https://doi.org/10.1111/j.0303-6987.2005.00281.x	NOUN
admet-2088	897	11	https://www.aimatmelanoma.org/stages-of-melanoma/	https://www.aimatmelanoma.org/stages-of-melanoma/	ADV
admet-2088	897	12	https://iv.iiarjournals.org/content/28/6/1005	https://iv.iiarjournals.org/content/28/6/1005	VERB
admet-2088	897	13	https://doi.org/10.4065/81.4.500	https://doi.org/10.4065/81.4.500	PROPN
admet-2088	897	14	https://doi.org/10.1016/j.suc.2019.09.005	https://doi.org/10.1016/j.suc.2019.09.005	VERB
admet-2088	897	15	http://dx.doi.org/10.1016/b978-0-12-802926-8.00016-1	http://dx.doi.org/10.1016/b978-0-12-802926-8.00016-1	ADV
admet-2088	897	16	https://doi.org/10.1016/j.cell.2012.06.024	https://doi.org/10.1016/j.cell.2012.06.024	VERB
admet-2088	897	17	https://hrcak.srce.hr/225444	https://hrcak.srce.hr/225444	PROPN
admet-2088	897	18	https://doi.org/10.1016/j.jddst.2023.104394	https://doi.org/10.1016/j.jddst.2023.104394	NOUN
admet-2088	897	19	https://doi.org/10.1158/0008-5472.can-03-3259	https://doi.org/10.1158/0008-5472.can-03-3259	X
admet-2088	897	20	https://doi.org/10.1038/nature10673	https://doi.org/10.1038/nature10673	PROPN
admet-2088	897	21	https://doi.org/10.1634/theoncologist.2010-0190	https://doi.org/10.1634/theoncologist.2010-0190	PROPN
admet-2088	897	22	https://www.jpsr.pharmainfo.in/documents/volumes/vol8issue02/jpsr08021610	https://www.jpsr.pharmainfo.in/documents/volumes/vol8issue02/jpsr08021610	PROPN
admet-2088	897	23	admet	admet	PROPN
admet-2088	897	24	&	&	CCONJ
admet-2088	897	25	dmpk	dmpk	PROPN
admet-2088	897	26	12(1	12(1	PROPN
admet-2088	897	27	)	)	PUNCT
admet-2088	897	28	(	(	PUNCT
admet-2088	897	29	2024	2024	NUM
admet-2088	897	30	)	)	PUNCT
admet-2088	897	31	107	107	NUM
admet-2088	897	32	-	-	SYM
admet-2088	897	33	150	150	NUM
admet-2088	897	34	nanomaterial	nanomaterial	NOUN
admet-2088	897	35	-	-	PUNCT
admet-2088	897	36	based	base	VERB
admet-2088	897	37	drug	drug	NOUN
admet-2088	897	38	delivery	delivery	NOUN
admet-2088	897	39	systems	system	NOUN
admet-2088	897	40	for	for	ADP
admet-2088	897	41	melanoma	melanoma	NOUN
admet-2088	897	42	therapy	therapy	NOUN
admet-2088	897	43	doi	doi	NOUN
admet-2088	897	44	:	:	PUNCT
admet-2088	897	45	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	898	1	139	139	NUM
admet-2088	898	2	ajcc	ajcc	PROPN
admet-2088	898	3	melanoma	melanoma	NOUN
admet-2088	898	4	staging	staging	NOUN
admet-2088	898	5	and	and	CCONJ
admet-2088	898	6	classification	classification	NOUN
admet-2088	898	7	.	.	PUNCT
admet-2088	899	1	journal	journal	NOUN
admet-2088	899	2	of	of	ADP
admet-2088	899	3	clinical	clinical	ADJ
admet-2088	899	4	oncology	oncology	NOUN
admet-2088	899	5	27	27	NUM
admet-2088	899	6	(	(	PUNCT
admet-2088	899	7	2009	2009	NUM
admet-2088	899	8	)	)	PUNCT
admet-2088	899	9	6199	6199	NUM
admet-2088	899	10	-	-	SYM
admet-2088	899	11	6206	6206	NUM
admet-2088	899	12	.	.	PUNCT
admet-2088	900	1	https://doi.org/10.1200/jco.2009.23.4799	https://doi.org/10.1200/jco.2009.23.4799	X
admet-2088	900	2	.	.	PUNCT
admet-2088	901	1	[	[	X
admet-2088	901	2	49	49	NUM
admet-2088	901	3	]	]	X
admet-2088	901	4	g.q	g.q	PROPN
admet-2088	901	5	.	.	PROPN
admet-2088	901	6	phan	phan	PROPN
admet-2088	901	7	,	,	PUNCT
admet-2088	901	8	p.	p.	PROPN
admet-2088	901	9	attia	attia	PROPN
admet-2088	901	10	,	,	PUNCT
admet-2088	901	11	s.m	s.m	PROPN
admet-2088	901	12	.	.	PROPN
admet-2088	901	13	steinberg	steinberg	PROPN
admet-2088	901	14	,	,	PUNCT
admet-2088	901	15	d.e	d.e	PROPN
admet-2088	901	16	.	.	PROPN
admet-2088	901	17	white	white	PROPN
admet-2088	901	18	,	,	PUNCT
admet-2088	901	19	s.a	s.a	PROPN
admet-2088	901	20	.	.	PROPN
admet-2088	901	21	rosenberg	rosenberg	PROPN
admet-2088	901	22	.	.	PUNCT
admet-2088	902	1	factors	factor	NOUN
admet-2088	902	2	associated	associate	VERB
admet-2088	902	3	with	with	ADP
admet-2088	902	4	response	response	NOUN
admet-2088	902	5	to	to	ADP
admet-2088	902	6	high	high	ADJ
admet-2088	902	7	-	-	PUNCT
admet-2088	902	8	dose	dose	NOUN
admet-2088	902	9	interleukin-2	interleukin-2	NOUN
admet-2088	902	10	in	in	ADP
admet-2088	902	11	patients	patient	NOUN
admet-2088	902	12	with	with	ADP
admet-2088	902	13	metastatic	metastatic	ADJ
admet-2088	902	14	melanoma	melanoma	NOUN
admet-2088	902	15	.	.	PUNCT
admet-2088	903	1	journal	journal	NOUN
admet-2088	903	2	of	of	ADP
admet-2088	903	3	clinical	clinical	ADJ
admet-2088	903	4	oncology	oncology	NOUN
admet-2088	903	5	19	19	NUM
admet-2088	903	6	(	(	PUNCT
admet-2088	903	7	2001	2001	NUM
admet-2088	903	8	)	)	PUNCT
admet-2088	903	9	3477	3477	NUM
admet-2088	903	10	-	-	SYM
admet-2088	903	11	3782	3782	NUM
admet-2088	903	12	.	.	PUNCT
admet-2088	904	1	https://doi.org/10.1200/jco.2001.19.15.3477	https://doi.org/10.1200/jco.2001.19.15.3477	NOUN
admet-2088	904	2	.	.	PUNCT
admet-2088	905	1	[	[	X
admet-2088	905	2	50	50	NUM
admet-2088	905	3	]	]	PUNCT
admet-2088	905	4	c.	c.	NOUN
admet-2088	905	5	beiu	beiu	PROPN
admet-2088	905	6	,	,	PUNCT
admet-2088	905	7	c.	c.	PROPN
admet-2088	905	8	giurcaneanu	giurcaneanu	PROPN
admet-2088	905	9	,	,	PUNCT
admet-2088	905	10	a.m.	a.m.	PROPN
admet-2088	905	11	grumezescu	grumezescu	PROPN
admet-2088	905	12	,	,	PUNCT
admet-2088	905	13	a.m.	a.m.	PROPN
admet-2088	905	14	holban	holban	PROPN
admet-2088	905	15	,	,	PUNCT
admet-2088	905	16	l.g	l.g	PROPN
admet-2088	905	17	.	.	PROPN
admet-2088	905	18	popa	popa	PROPN
admet-2088	905	19	,	,	PUNCT
admet-2088	905	20	m.m	m.m	PROPN
admet-2088	905	21	.	.	PROPN
admet-2088	905	22	mihai	mihai	PROPN
admet-2088	905	23	,	,	PUNCT
admet-2088	905	24	nanosystems	nanosystem	VERB
admet-2088	905	25	for	for	ADP
admet-2088	905	26	improved	improved	ADJ
admet-2088	905	27	targeted	target	VERB
admet-2088	905	28	therapies	therapy	NOUN
admet-2088	905	29	in	in	ADP
admet-2088	905	30	melanoma	melanoma	NOUN
admet-2088	905	31	.	.	PUNCT
admet-2088	906	1	journal	journal	NOUN
admet-2088	906	2	of	of	ADP
admet-2088	906	3	clinical	clinical	ADJ
admet-2088	906	4	medicine	medicine	NOUN
admet-2088	906	5	9	9	NUM
admet-2088	906	6	(	(	PUNCT
admet-2088	906	7	2020	2020	NUM
admet-2088	906	8	)	)	PUNCT
admet-2088	906	9	318	318	NUM
admet-2088	906	10	.	.	PUNCT
admet-2088	906	11	https://doi.org/10.3390/jcm9020318	https://doi.org/10.3390/jcm9020318	NOUN
admet-2088	906	12	.	.	PUNCT
admet-2088	907	1	[	[	X
admet-2088	907	2	51	51	NUM
admet-2088	907	3	]	]	PUNCT
admet-2088	907	4	k.	k.	PROPN
admet-2088	908	1	smetana	smetana	PROPN
admet-2088	909	1	jr	jr	PROPN
admet-2088	909	2	.	.	PROPN
admet-2088	909	3	,	,	PUNCT
admet-2088	909	4	l.	l.	PROPN
admet-2088	909	5	lacina	lacina	PROPN
admet-2088	909	6	,	,	PUNCT
admet-2088	909	7	o.	o.	PROPN
admet-2088	909	8	kodet	kodet	PROPN
admet-2088	909	9	,	,	PUNCT
admet-2088	909	10	targeted	target	VERB
admet-2088	909	11	therapies	therapy	NOUN
admet-2088	909	12	for	for	ADP
admet-2088	909	13	melanoma	melanoma	NOUN
admet-2088	909	14	.	.	PUNCT
admet-2088	910	1	cancers	cancer	NOUN
admet-2088	910	2	12	12	NUM
admet-2088	910	3	(	(	PUNCT
admet-2088	910	4	2020	2020	NUM
admet-2088	910	5	)	)	PUNCT
admet-2088	910	6	2494	2494	NUM
admet-2088	910	7	.	.	PUNCT
admet-2088	911	1	https://doi.org/10.3390/cancers12092494	https://doi.org/10.3390/cancers12092494	NOUN
admet-2088	911	2	.	.	PUNCT
admet-2088	912	1	[	[	X
admet-2088	912	2	52	52	NUM
admet-2088	912	3	]	]	PUNCT
admet-2088	912	4	[	[	X
admet-2088	912	5	58	58	NUM
admet-2088	912	6	]	]	X
admet-2088	912	7	p.a	p.a	PROPN
admet-2088	912	8	.	.	PROPN
admet-2088	912	9	ascierto	ascierto	PROPN
admet-2088	912	10	,	,	PUNCT
admet-2088	912	11	k.	k.	PROPN
admet-2088	912	12	flaherty	flaherty	PROPN
admet-2088	912	13	,	,	PUNCT
admet-2088	912	14	s.	s.	PROPN
admet-2088	912	15	goff	goff	PROPN
admet-2088	912	16	.	.	PUNCT
admet-2088	913	1	emerging	emerge	VERB
admet-2088	913	2	strategies	strategy	NOUN
admet-2088	913	3	in	in	ADP
admet-2088	913	4	systemic	systemic	ADJ
admet-2088	913	5	therapy	therapy	NOUN
admet-2088	913	6	for	for	ADP
admet-2088	913	7	the	the	DET
admet-2088	913	8	treatment	treatment	NOUN
admet-2088	913	9	of	of	ADP
admet-2088	913	10	melanoma	melanoma	NOUN
admet-2088	913	11	.	.	PUNCT
admet-2088	914	1	american	american	ADJ
admet-2088	914	2	society	society	NOUN
admet-2088	914	3	of	of	ADP
admet-2088	914	4	clinical	clinical	ADJ
admet-2088	914	5	oncology	oncology	NOUN
admet-2088	914	6	educational	educational	ADJ
admet-2088	914	7	38	38	NUM
admet-2088	914	8	(	(	PUNCT
admet-2088	914	9	2018	2018	NUM
admet-2088	914	10	)	)	PUNCT
admet-2088	914	11	751	751	NUM
admet-2088	914	12	-	-	SYM
admet-2088	914	13	758	758	NUM
admet-2088	914	14	.	.	PUNCT
admet-2088	915	1	https://doi.org/10.1200/edbk_199047	https://doi.org/10.1200/edbk_199047	ADJ
admet-2088	915	2	.	.	PUNCT
admet-2088	916	1	[	[	X
admet-2088	916	2	53	53	NUM
admet-2088	916	3	]	]	X
admet-2088	916	4	r.b	r.b	PROPN
admet-2088	916	5	.	.	PROPN
admet-2088	916	6	rigon	rigon	PROPN
admet-2088	916	7	,	,	PUNCT
admet-2088	916	8	m.h	m.h	PROPN
admet-2088	916	9	.	.	PROPN
admet-2088	916	10	oyafuso	oyafuso	PROPN
admet-2088	916	11	,	,	PUNCT
admet-2088	916	12	a.t	a.t	PROPN
admet-2088	916	13	.	.	PROPN
admet-2088	916	14	fujimura	fujimura	PROPN
admet-2088	916	15	,	,	PUNCT
admet-2088	916	16	m.l	m.l	PROPN
admet-2088	916	17	.	.	PROPN
admet-2088	916	18	gonçalez	gonçalez	PROPN
admet-2088	916	19	,	,	PUNCT
admet-2088	916	20	a.h.d	a.h.d	PROPN
admet-2088	916	21	.	.	PUNCT
admet-2088	917	1	prado	prado	PROPN
admet-2088	917	2	,	,	PUNCT
admet-2088	917	3	m.p.d	m.p.d	NOUN
admet-2088	917	4	.	.	PROPN
admet-2088	917	5	gremiao	gremiao	PROPN
admet-2088	917	6	,	,	PUNCT
admet-2088	917	7	m.	m.	NOUN
admet-2088	917	8	chorilli	chorilli	PROPN
admet-2088	917	9	.	.	PUNCT
admet-2088	918	1	nanotechnology	nanotechnology	NOUN
admet-2088	918	2	-	-	PUNCT
admet-2088	918	3	based	base	VERB
admet-2088	918	4	drug	drug	NOUN
admet-2088	918	5	delivery	delivery	NOUN
admet-2088	918	6	systems	system	NOUN
admet-2088	918	7	for	for	ADP
admet-2088	918	8	melanoma	melanoma	ADJ
admet-2088	918	9	antitumoral	antitumoral	ADJ
admet-2088	918	10	therapy	therapy	NOUN
admet-2088	918	11	.	.	PUNCT
admet-2088	918	12	biomed	biome	VERB
admet-2088	918	13	research	research	NOUN
admet-2088	918	14	international	international	ADJ
admet-2088	918	15	2015	2015	NUM
admet-2088	918	16	(	(	PUNCT
admet-2088	918	17	2015	2015	NUM
admet-2088	918	18	)	)	PUNCT
admet-2088	918	19	841817	841817	NUM
admet-2088	918	20	.	.	PUNCT
admet-2088	919	1	https://doi.org/10.1155/2015/841817	https://doi.org/10.1155/2015/841817	NOUN
admet-2088	919	2	.	.	PUNCT
admet-2088	920	1	[	[	X
admet-2088	920	2	54	54	NUM
admet-2088	920	3	]	]	SYM
admet-2088	920	4	s.c	s.c	PROPN
admet-2088	920	5	.	.	PROPN
admet-2088	920	6	weinmann	weinmann	PROPN
admet-2088	920	7	,	,	PUNCT
admet-2088	920	8	d.s	d.s	PROPN
admet-2088	920	9	.	.	PROPN
admet-2088	920	10	pisetsky	pisetsky	PROPN
admet-2088	920	11	.	.	PUNCT
admet-2088	921	1	mechanisms	mechanism	NOUN
admet-2088	921	2	of	of	ADP
admet-2088	921	3	immune	immune	NOUN
admet-2088	921	4	-	-	PUNCT
admet-2088	921	5	related	relate	VERB
admet-2088	921	6	adverse	adverse	ADJ
admet-2088	921	7	events	event	NOUN
admet-2088	921	8	during	during	ADP
admet-2088	921	9	the	the	DET
admet-2088	921	10	treatment	treatment	NOUN
admet-2088	921	11	of	of	ADP
admet-2088	921	12	cancer	cancer	NOUN
admet-2088	921	13	with	with	ADP
admet-2088	921	14	immune	immune	ADJ
admet-2088	921	15	checkpoint	checkpoint	NOUN
admet-2088	921	16	inhibitors	inhibitor	NOUN
admet-2088	921	17	.	.	PUNCT
admet-2088	922	1	rheumatology	rheumatology	NOUN
admet-2088	922	2	58(suppl	58(suppl	NUM
admet-2088	922	3	7	7	NUM
admet-2088	922	4	)	)	PUNCT
admet-2088	922	5	(	(	PUNCT
admet-2088	922	6	2019	2019	NUM
admet-2088	922	7	)	)	PUNCT
admet-2088	922	8	vii59	vii59	NOUN
admet-2088	922	9	-	-	PUNCT
admet-2088	922	10	vii67	vii67	PROPN
admet-2088	922	11	.	.	PUNCT
admet-2088	923	1	https://doi.org/10.1093/rheumatology/kez308	https://doi.org/10.1093/rheumatology/kez308	PROPN
admet-2088	923	2	.	.	PUNCT
admet-2088	924	1	[	[	X
admet-2088	924	2	55	55	NUM
admet-2088	924	3	]	]	X
admet-2088	924	4	c.	c.	PROPN
admet-2088	924	5	robert	robert	PROPN
admet-2088	924	6	,	,	PUNCT
admet-2088	924	7	a.	a.	PROPN
admet-2088	924	8	ribas	ribas	PROPN
admet-2088	924	9	,	,	PUNCT
admet-2088	924	10	j.d	j.d	PROPN
admet-2088	924	11	.	.	PROPN
admet-2088	924	12	wolchok	wolchok	PROPN
admet-2088	924	13	,	,	PUNCT
admet-2088	924	14	f.s	f.s	PROPN
admet-2088	924	15	.	.	PROPN
admet-2088	924	16	hodi	hodi	PROPN
admet-2088	924	17	,	,	PUNCT
admet-2088	924	18	o.	o.	PROPN
admet-2088	924	19	hamid	hamid	PROPN
admet-2088	924	20	,	,	PUNCT
admet-2088	924	21	r.	r.	PROPN
admet-2088	924	22	kefford	kefford	PROPN
admet-2088	924	23	,	,	PUNCT
admet-2088	924	24	j.s	j.s	PROPN
admet-2088	924	25	.	.	PROPN
admet-2088	924	26	weber	weber	PROPN
admet-2088	924	27	,	,	PUNCT
admet-2088	924	28	a.m.	a.m.	PROPN
admet-2088	924	29	joshua	joshua	PROPN
admet-2088	924	30	,	,	PUNCT
admet-2088	924	31	w.-j	w.-j	PROPN
admet-2088	924	32	.	.	PUNCT
admet-2088	925	1	hwu	hwu	PROPN
admet-2088	925	2	,	,	PUNCT
admet-2088	925	3	t.c	t.c	PROPN
admet-2088	925	4	.	.	PROPN
admet-2088	925	5	gangadhar	gangadhar	PROPN
admet-2088	925	6	,	,	PUNCT
admet-2088	925	7	a.	a.	NOUN
admet-2088	925	8	patnaik	patnaik	PROPN
admet-2088	925	9	,	,	PUNCT
admet-2088	925	10	r.	r.	PROPN
admet-2088	925	11	dronca	dronca	PROPN
admet-2088	925	12	,	,	PUNCT
admet-2088	925	13	h.	h.	PROPN
admet-2088	925	14	zarour	zarour	PROPN
admet-2088	925	15	,	,	PUNCT
admet-2088	925	16	r.w	r.w	PROPN
admet-2088	925	17	.	.	PROPN
admet-2088	925	18	joseph	joseph	PROPN
admet-2088	925	19	,	,	PUNCT
admet-2088	925	20	p.	p.	PROPN
admet-2088	925	21	boasberg	boasberg	PROPN
admet-2088	925	22	,	,	PUNCT
admet-2088	925	23	b.	b.	PROPN
admet-2088	925	24	chmielowski	chmielowski	PROPN
admet-2088	925	25	,	,	PUNCT
admet-2088	925	26	c.	c.	PROPN
admet-2088	925	27	mateus	mateus	PROPN
admet-2088	925	28	,	,	PUNCT
admet-2088	925	29	m.a	m.a	PROPN
admet-2088	925	30	.	.	PROPN
admet-2088	925	31	postow	postow	PROPN
admet-2088	925	32	,	,	PUNCT
admet-2088	925	33	k.	k.	PROPN
admet-2088	925	34	gergich	gergich	PROPN
admet-2088	925	35	,	,	PUNCT
admet-2088	925	36	j.	j.	PROPN
admet-2088	925	37	elassaiss	elassaiss	PROPN
admet-2088	925	38	-	-	PUNCT
admet-2088	925	39	schaap	schaap	PROPN
admet-2088	925	40	,	,	PUNCT
admet-2088	925	41	x.n	x.n	PROPN
admet-2088	925	42	.	.	PUNCT
admet-2088	925	43	li	li	PROPN
admet-2088	925	44	,	,	PUNCT
admet-2088	925	45	r.	r.	PROPN
admet-2088	925	46	iannone	iannone	PROPN
admet-2088	925	47	,	,	PUNCT
admet-2088	925	48	s.w	s.w	PROPN
admet-2088	925	49	.	.	PROPN
admet-2088	925	50	ebbinghaus	ebbinghaus	PROPN
admet-2088	925	51	,	,	PUNCT
admet-2088	925	52	s.p	s.p	PROPN
admet-2088	925	53	.	.	PROPN
admet-2088	925	54	kang	kang	PROPN
admet-2088	925	55	,	,	PUNCT
admet-2088	925	56	a.	a.	PROPN
admet-2088	925	57	daud	daud	PROPN
admet-2088	925	58	.	.	PUNCT
admet-2088	926	1	antiprogrammed	antiprogramme	VERB
admet-2088	926	2	-	-	PUNCT
admet-2088	926	3	death	death	NOUN
admet-2088	926	4	-	-	PUNCT
admet-2088	926	5	receptor-1	receptor-1	NUM
admet-2088	926	6	treatment	treatment	NOUN
admet-2088	926	7	with	with	ADP
admet-2088	926	8	pembrolizumab	pembrolizumab	NOUN
admet-2088	926	9	in	in	ADP
admet-2088	926	10	ipilimumabrefractory	ipilimumabrefractory	ADJ
admet-2088	926	11	advanced	advanced	ADJ
admet-2088	926	12	melanoma	melanoma	NOUN
admet-2088	926	13	:	:	PUNCT
admet-2088	926	14	a	a	DET
admet-2088	926	15	randomised	randomise	VERB
admet-2088	926	16	dose	dose	NOUN
admet-2088	926	17	-	-	PUNCT
admet-2088	926	18	comparison	comparison	NOUN
admet-2088	926	19	cohort	cohort	NOUN
admet-2088	926	20	of	of	ADP
admet-2088	926	21	a	a	DET
admet-2088	926	22	phase	phase	NOUN
admet-2088	926	23	1	1	NUM
admet-2088	926	24	trial	trial	NOUN
admet-2088	926	25	.	.	PUNCT
admet-2088	927	1	lancet	lancet	PROPN
admet-2088	927	2	384	384	NUM
admet-2088	927	3	(	(	PUNCT
admet-2088	927	4	2014	2014	NUM
admet-2088	927	5	)	)	PUNCT
admet-2088	927	6	1109	1109	NUM
admet-2088	927	7	-	-	SYM
admet-2088	927	8	1117	1117	NUM
admet-2088	927	9	.	.	PUNCT
admet-2088	928	1	https://doi.org/10.1016/s0140-6736(14)60958-2	https://doi.org/10.1016/s0140-6736(14)60958-2	NOUN
admet-2088	928	2	.	.	PUNCT
admet-2088	929	1	[	[	X
admet-2088	929	2	56	56	NUM
admet-2088	929	3	]	]	X
admet-2088	929	4	s.l	s.l	PROPN
admet-2088	929	5	.	.	PROPN
admet-2088	929	6	topalian	topalian	PROPN
admet-2088	929	7	,	,	PUNCT
admet-2088	929	8	m.	m.	NOUN
admet-2088	929	9	sznol	sznol	PROPN
admet-2088	929	10	,	,	PUNCT
admet-2088	929	11	d.f	d.f	PROPN
admet-2088	929	12	.	.	PROPN
admet-2088	929	13	mcdermott	mcdermott	PROPN
admet-2088	929	14	,	,	PUNCT
admet-2088	929	15	h.m	h.m	PROPN
admet-2088	929	16	.	.	PROPN
admet-2088	929	17	kluger	kluger	PROPN
admet-2088	929	18	,	,	PUNCT
admet-2088	929	19	r.d	r.d	PROPN
admet-2088	929	20	.	.	PROPN
admet-2088	929	21	carvajal	carvajal	PROPN
admet-2088	929	22	,	,	PUNCT
admet-2088	929	23	w.h	w.h	PROPN
admet-2088	929	24	.	.	PROPN
admet-2088	929	25	sharfman	sharfman	PROPN
admet-2088	929	26	,	,	PUNCT
admet-2088	929	27	j.r	j.r	PROPN
admet-2088	929	28	.	.	PROPN
admet-2088	929	29	brahmer	brahmer	PROPN
admet-2088	929	30	,	,	PUNCT
admet-2088	929	31	d.p	d.p	PROPN
admet-2088	929	32	.	.	PROPN
admet-2088	929	33	lawrence	lawrence	PROPN
admet-2088	929	34	,	,	PUNCT
admet-2088	929	35	m.b	m.b	PROPN
admet-2088	929	36	.	.	PROPN
admet-2088	929	37	atkins	atkins	PROPN
admet-2088	929	38	,	,	PUNCT
admet-2088	929	39	j.d	j.d	PROPN
admet-2088	929	40	.	.	PROPN
admet-2088	929	41	powderly	powderly	PROPN
admet-2088	929	42	,	,	PUNCT
admet-2088	929	43	p.d	p.d	PROPN
admet-2088	929	44	.	.	PROPN
admet-2088	929	45	leming	leming	PROPN
admet-2088	929	46	,	,	PUNCT
admet-2088	929	47	e.j	e.j	PROPN
admet-2088	929	48	.	.	PROPN
admet-2088	929	49	lipson	lipson	PROPN
admet-2088	929	50	,	,	PUNCT
admet-2088	929	51	i.	i.	PROPN
admet-2088	929	52	puzanov	puzanov	PROPN
admet-2088	929	53	,	,	PUNCT
admet-2088	929	54	d.c	d.c	PROPN
admet-2088	929	55	.	.	PROPN
admet-2088	929	56	smith	smith	PROPN
admet-2088	929	57	,	,	PUNCT
admet-2088	929	58	j.m	j.m	PROPN
admet-2088	929	59	.	.	PROPN
admet-2088	929	60	taube	taube	PROPN
admet-2088	929	61	,	,	PUNCT
admet-2088	929	62	j.m	j.m	PROPN
admet-2088	929	63	.	.	PROPN
admet-2088	929	64	wigginton	wigginton	PROPN
admet-2088	929	65	,	,	PUNCT
admet-2088	929	66	g.d	g.d	PROPN
admet-2088	929	67	.	.	PROPN
admet-2088	929	68	kollia	kollia	PROPN
admet-2088	929	69	,	,	PUNCT
admet-2088	929	70	a.	a.	PROPN
admet-2088	929	71	gupta	gupta	PROPN
admet-2088	929	72	,	,	PUNCT
admet-2088	929	73	d.m	d.m	PROPN
admet-2088	929	74	.	.	PROPN
admet-2088	929	75	pardoll	pardoll	PROPN
admet-2088	929	76	,	,	PUNCT
admet-2088	929	77	j.a	j.a	PROPN
admet-2088	929	78	.	.	PROPN
admet-2088	929	79	sosman	sosman	PROPN
admet-2088	929	80	,	,	PUNCT
admet-2088	929	81	f.s	f.s	PROPN
admet-2088	929	82	.	.	PROPN
admet-2088	929	83	hodi	hodi	PROPN
admet-2088	929	84	.	.	PUNCT
admet-2088	930	1	survival	survival	NOUN
admet-2088	930	2	,	,	PUNCT
admet-2088	930	3	durable	durable	ADJ
admet-2088	930	4	tumor	tumor	NOUN
admet-2088	930	5	remission	remission	NOUN
admet-2088	930	6	,	,	PUNCT
admet-2088	930	7	and	and	CCONJ
admet-2088	930	8	long	long	ADJ
admet-2088	930	9	-	-	PUNCT
admet-2088	930	10	term	term	NOUN
admet-2088	930	11	safety	safety	NOUN
admet-2088	930	12	in	in	ADP
admet-2088	930	13	patients	patient	NOUN
admet-2088	930	14	with	with	ADP
admet-2088	930	15	advanced	advanced	ADJ
admet-2088	930	16	melanoma	melanoma	NOUN
admet-2088	930	17	receiving	receive	VERB
admet-2088	930	18	nivolumab	nivolumab	NOUN
admet-2088	930	19	.	.	PUNCT
admet-2088	931	1	journal	journal	NOUN
admet-2088	931	2	of	of	ADP
admet-2088	931	3	clinical	clinical	ADJ
admet-2088	931	4	oncology	oncology	NOUN
admet-2088	931	5	32	32	NUM
admet-2088	931	6	(	(	PUNCT
admet-2088	931	7	2014	2014	NUM
admet-2088	931	8	)	)	PUNCT
admet-2088	931	9	1020	1020	NUM
admet-2088	931	10	-	-	SYM
admet-2088	931	11	1030	1030	NUM
admet-2088	931	12	.	.	PUNCT
admet-2088	932	1	https://doi.org/10.1200/jco.2013.53.0105	https://doi.org/10.1200/jco.2013.53.0105	NOUN
admet-2088	932	2	.	.	PUNCT
admet-2088	933	1	[	[	X
admet-2088	933	2	57	57	NUM
admet-2088	933	3	]	]	X
admet-2088	933	4	m.a	m.a	PROPN
admet-2088	933	5	.	.	PROPN
admet-2088	933	6	tran	tran	PROPN
admet-2088	933	7	,	,	PUNCT
admet-2088	933	8	r.	r.	PROPN
admet-2088	933	9	gowda	gowda	PROPN
admet-2088	933	10	,	,	PUNCT
admet-2088	933	11	a.	a.	PROPN
admet-2088	933	12	sharma	sharma	PROPN
admet-2088	933	13	,	,	PUNCT
admet-2088	933	14	e.-j	e.-j	PROPN
admet-2088	933	15	.	.	PROPN
admet-2088	933	16	park	park	PROPN
admet-2088	933	17	,	,	PUNCT
admet-2088	933	18	j.	j.	PROPN
admet-2088	933	19	adair	adair	PROPN
admet-2088	933	20	,	,	PUNCT
admet-2088	933	21	m.	m.	NOUN
admet-2088	933	22	kester	kester	PROPN
admet-2088	933	23	,	,	PUNCT
admet-2088	933	24	n.b	n.b	PROPN
admet-2088	933	25	.	.	PROPN
admet-2088	933	26	smith	smith	PROPN
admet-2088	933	27	,	,	PUNCT
admet-2088	933	28	g.p	g.p	PROPN
admet-2088	933	29	.	.	PROPN
admet-2088	933	30	robertson	robertson	PROPN
admet-2088	933	31	.	.	PUNCT
admet-2088	934	1	targeting	target	VERB
admet-2088	934	2	v600eb	v600eb	NOUN
admet-2088	934	3	-	-	PUNCT
admet-2088	934	4	raf	raf	PROPN
admet-2088	934	5	and	and	CCONJ
admet-2088	934	6	akt3	akt3	NOUN
admet-2088	934	7	using	use	VERB
admet-2088	934	8	nanoliposomal	nanoliposomal	ADJ
admet-2088	934	9	-	-	PUNCT
admet-2088	934	10	small	small	ADJ
admet-2088	934	11	interfering	interfere	VERB
admet-2088	934	12	rna	rna	NOUN
admet-2088	934	13	inhibits	inhibit	VERB
admet-2088	934	14	cutaneous	cutaneous	ADJ
admet-2088	934	15	melanocytic	melanocytic	ADJ
admet-2088	934	16	lesion	lesion	NOUN
admet-2088	934	17	development	development	NOUN
admet-2088	934	18	.	.	PUNCT
admet-2088	935	1	cancer	cancer	NOUN
admet-2088	935	2	research	research	NOUN
admet-2088	935	3	68	68	NUM
admet-2088	935	4	(	(	PUNCT
admet-2088	935	5	2008	2008	NUM
admet-2088	935	6	)	)	PUNCT
admet-2088	935	7	7638	7638	NUM
admet-2088	935	8	-	-	SYM
admet-2088	935	9	7649	7649	NUM
admet-2088	935	10	.	.	PUNCT
admet-2088	936	1	https://doi.org/10.1158/0008-5472.can-07-6614	https://doi.org/10.1158/0008-5472.can-07-6614	X
admet-2088	936	2	.	.	PUNCT
admet-2088	937	1	[	[	X
admet-2088	937	2	58	58	NUM
admet-2088	937	3	]	]	PUNCT
admet-2088	937	4	s.	s.	PROPN
admet-2088	937	5	dasari	dasari	PROPN
admet-2088	937	6	,	,	PUNCT
admet-2088	937	7	c.g	c.g	PROPN
admet-2088	937	8	.	.	PROPN
admet-2088	937	9	yedjou	yedjou	PROPN
admet-2088	937	10	,	,	PUNCT
admet-2088	937	11	r.t	r.t	PROPN
admet-2088	937	12	.	.	PROPN
admet-2088	937	13	brodell	brodell	PROPN
admet-2088	937	14	,	,	PUNCT
admet-2088	937	15	a.r	a.r	PROPN
admet-2088	937	16	.	.	PROPN
admet-2088	937	17	cruse	cruse	PROPN
admet-2088	937	18	,	,	PUNCT
admet-2088	937	19	p.b	p.b	PROPN
admet-2088	937	20	.	.	PROPN
admet-2088	937	21	tchounwou	tchounwou	PROPN
admet-2088	937	22	,	,	PUNCT
admet-2088	937	23	therapeutic	therapeutic	ADJ
admet-2088	937	24	strategies	strategy	NOUN
admet-2088	937	25	and	and	CCONJ
admet-2088	937	26	potential	potential	ADJ
admet-2088	937	27	implications	implication	NOUN
admet-2088	937	28	of	of	ADP
admet-2088	937	29	silver	silver	ADJ
admet-2088	937	30	nanoparticles	nanoparticle	NOUN
admet-2088	937	31	in	in	ADP
admet-2088	937	32	the	the	DET
admet-2088	937	33	management	management	NOUN
admet-2088	937	34	of	of	ADP
admet-2088	937	35	skin	skin	NOUN
admet-2088	937	36	cancer	cancer	NOUN
admet-2088	937	37	.	.	PUNCT
admet-2088	938	1	nanotechnology	nanotechnology	NOUN
admet-2088	938	2	reviews	review	VERB
admet-2088	938	3	9	9	NUM
admet-2088	938	4	(	(	PUNCT
admet-2088	938	5	2020	2020	NUM
admet-2088	938	6	)	)	PUNCT
admet-2088	938	7	1500	1500	NUM
admet-2088	938	8	-	-	SYM
admet-2088	938	9	1521	1521	NUM
admet-2088	938	10	.	.	PUNCT
admet-2088	939	1	https://doi.org/10.1515/ntrev-2020-0117	https://doi.org/10.1515/ntrev-2020-0117	NOUN
admet-2088	939	2	.	.	PUNCT
admet-2088	940	1	[	[	X
admet-2088	940	2	59	59	NUM
admet-2088	940	3	]	]	PUNCT
admet-2088	940	4	j.	j.	PROPN
admet-2088	940	5	zhao	zhao	PROPN
admet-2088	940	6	,	,	PUNCT
admet-2088	940	7	n.	n.	PROPN
admet-2088	940	8	gao	gao	PROPN
admet-2088	940	9	,	,	PUNCT
admet-2088	940	10	j.	j.	PROPN
admet-2088	940	11	xu	xu	PROPN
admet-2088	940	12	,	,	PUNCT
admet-2088	940	13	x.	x.	PROPN
admet-2088	940	14	zhu	zhu	PROPN
admet-2088	940	15	,	,	PUNCT
admet-2088	940	16	g.	g.	PROPN
admet-2088	940	17	ling	ling	PROPN
admet-2088	940	18	,	,	PUNCT
admet-2088	940	19	p.	p.	PROPN
admet-2088	940	20	zhang	zhang	PROPN
admet-2088	940	21	.	.	PUNCT
admet-2088	940	22	novel	novel	ADJ
admet-2088	940	23	strategies	strategy	NOUN
admet-2088	940	24	in	in	ADP
admet-2088	940	25	melanoma	melanoma	NOUN
admet-2088	940	26	treatment	treatment	NOUN
admet-2088	940	27	using	use	VERB
admet-2088	940	28	silver	silver	ADJ
admet-2088	940	29	nanoparticles	nanoparticle	NOUN
admet-2088	940	30	.	.	PUNCT
admet-2088	941	1	cancer	cancer	NOUN
admet-2088	941	2	letters	letter	NOUN
admet-2088	941	3	561	561	NUM
admet-2088	941	4	(	(	PUNCT
admet-2088	941	5	2023	2023	NUM
admet-2088	941	6	)	)	PUNCT
admet-2088	941	7	216148	216148	NUM
admet-2088	941	8	.	.	PUNCT
admet-2088	942	1	https://doi.org/10.1016/j.canlet.2023.216148	https://doi.org/10.1016/j.canlet.2023.216148	NOUN
admet-2088	942	2	.	.	PUNCT
admet-2088	943	1	[	[	X
admet-2088	943	2	60	60	NUM
admet-2088	943	3	]	]	X
admet-2088	943	4	d.	d.	PROPN
admet-2088	943	5	kim	kim	PROPN
admet-2088	943	6	,	,	PUNCT
admet-2088	943	7	r.	r.	PROPN
admet-2088	943	8	amatya	amatya	PROPN
admet-2088	943	9	,	,	PUNCT
admet-2088	943	10	s.	s.	PROPN
admet-2088	943	11	hwang	hwang	PROPN
admet-2088	943	12	,	,	PUNCT
admet-2088	943	13	s.	s.	PROPN
admet-2088	943	14	lee	lee	PROPN
admet-2088	943	15	,	,	PUNCT
admet-2088	943	16	k.a	k.a	PROPN
admet-2088	943	17	.	.	PROPN
admet-2088	943	18	min	min	PROPN
admet-2088	943	19	,	,	PUNCT
admet-2088	943	20	m.c	m.c	PROPN
admet-2088	943	21	.	.	PROPN
admet-2088	943	22	shin	shin	PROPN
admet-2088	943	23	.	.	PUNCT
admet-2088	944	1	bsa	bsa	PROPN
admet-2088	944	2	-	-	ADJ
admet-2088	944	3	silver	silver	ADJ
admet-2088	944	4	nanoparticles	nanoparticle	NOUN
admet-2088	944	5	:	:	PUNCT
admet-2088	944	6	a	a	DET
admet-2088	944	7	potential	potential	ADJ
admet-2088	944	8	multimodal	multimodal	NOUN
admet-2088	944	9	therapeutics	therapeutic	NOUN
admet-2088	944	10	for	for	ADP
admet-2088	944	11	conventional	conventional	ADJ
admet-2088	944	12	and	and	CCONJ
admet-2088	944	13	photothermal	photothermal	ADJ
admet-2088	944	14	treatment	treatment	NOUN
admet-2088	944	15	of	of	ADP
admet-2088	944	16	skin	skin	NOUN
admet-2088	944	17	cancer	cancer	NOUN
admet-2088	944	18	.	.	PUNCT
admet-2088	945	1	pharmaceutics	pharmaceutic	NOUN
admet-2088	945	2	13	13	NUM
admet-2088	945	3	(	(	PUNCT
admet-2088	945	4	2021	2021	NUM
admet-2088	945	5	)	)	PUNCT
admet-2088	945	6	575	575	NUM
admet-2088	945	7	.	.	PUNCT
admet-2088	946	1	https://doi.org/10.3390/pharmaceutics13040575	https://doi.org/10.3390/pharmaceutics13040575	PROPN
admet-2088	946	2	.	.	PUNCT
admet-2088	947	1	[	[	X
admet-2088	947	2	61	61	NUM
admet-2088	947	3	]	]	PUNCT
admet-2088	947	4	t.	t.	NOUN
admet-2088	947	5	park	park	NOUN
admet-2088	947	6	,	,	PUNCT
admet-2088	947	7	s.	s.	PROPN
admet-2088	947	8	lee	lee	PROPN
admet-2088	947	9	,	,	PUNCT
admet-2088	947	10	r.	r.	PROPN
admet-2088	947	11	amatya	amatya	PROPN
admet-2088	947	12	,	,	PUNCT
admet-2088	947	13	h.	h.	PROPN
admet-2088	947	14	cheong	cheong	PROPN
admet-2088	947	15	,	,	PUNCT
admet-2088	947	16	c.	c.	PROPN
admet-2088	947	17	moon	moon	PROPN
admet-2088	947	18	,	,	PUNCT
admet-2088	947	19	h.d	h.d	PROPN
admet-2088	947	20	.	.	PROPN
admet-2088	947	21	kwak	kwak	PROPN
admet-2088	947	22	,	,	PUNCT
admet-2088	947	23	k.a	k.a	PROPN
admet-2088	947	24	.	.	PROPN
admet-2088	947	25	min	min	PROPN
admet-2088	947	26	,	,	PUNCT
admet-2088	947	27	m.c	m.c	PROPN
admet-2088	947	28	.	.	PROPN
admet-2088	947	29	shin	shin	PROPN
admet-2088	947	30	.	.	PUNCT
admet-2088	948	1	icg	icg	NOUN
admet-2088	948	2	-	-	PUNCT
admet-2088	948	3	loaded	load	VERB
admet-2088	948	4	pegylated	pegylate	VERB
admet-2088	948	5	bsa	bsa	NOUN
admet-2088	948	6	-	-	ADJ
admet-2088	948	7	silver	silver	ADJ
admet-2088	948	8	nanoparticles	nanoparticle	NOUN
admet-2088	948	9	for	for	ADP
admet-2088	948	10	effective	effective	ADJ
admet-2088	948	11	photothermal	photothermal	ADJ
admet-2088	948	12	cancer	cancer	NOUN
admet-2088	948	13	therapy	therapy	NOUN
admet-2088	948	14	.	.	PUNCT
admet-2088	949	1	international	international	ADJ
admet-2088	949	2	journal	journal	PROPN
admet-2088	949	3	of	of	ADP
admet-2088	949	4	nanomedicine	nanomedicine	NOUN
admet-2088	949	5	15	15	NUM
admet-2088	949	6	(	(	PUNCT
admet-2088	949	7	2020	2020	NUM
admet-2088	949	8	)	)	PUNCT
admet-2088	949	9	5459	5459	NUM
admet-2088	949	10	-	-	SYM
admet-2088	949	11	5471	5471	NUM
admet-2088	949	12	.	.	PUNCT
admet-2088	950	1	https://doi.org/10.2147/ijn.s255874	https://doi.org/10.2147/ijn.s255874	NUM
admet-2088	950	2	.	.	PUNCT
admet-2088	951	1	[	[	X
admet-2088	951	2	62	62	NUM
admet-2088	951	3	]	]	X
admet-2088	951	4	j.m	j.m	PROPN
admet-2088	951	5	.	.	PROPN
admet-2088	951	6	kasprzak	kasprzak	PROPN
admet-2088	951	7	,	,	PUNCT
admet-2088	951	8	y.g	y.g	PROPN
admet-2088	951	9	.	.	PROPN
admet-2088	951	10	xu	xu	PROPN
admet-2088	951	11	.	.	PUNCT
admet-2088	952	1	diagnosis	diagnosis	NOUN
admet-2088	952	2	and	and	CCONJ
admet-2088	952	3	management	management	NOUN
admet-2088	952	4	of	of	ADP
admet-2088	952	5	lentigo	lentigo	ADJ
admet-2088	952	6	maligna	maligna	PROPN
admet-2088	952	7	:	:	PUNCT
admet-2088	952	8	a	a	DET
admet-2088	952	9	review	review	NOUN
admet-2088	952	10	.	.	PUNCT
admet-2088	953	1	drugs	drug	NOUN
admet-2088	953	2	context	context	VERB
admet-2088	953	3	4	4	NUM
admet-2088	953	4	(	(	PUNCT
admet-2088	953	5	2015	2015	NUM
admet-2088	953	6	)	)	PUNCT
admet-2088	953	7	212281	212281	NUM
admet-2088	953	8	.	.	PUNCT
admet-2088	954	1	https://doi.org/10.7573/2fdic.212281	https://doi.org/10.7573/2fdic.212281	PROPN
admet-2088	954	2	.	.	PUNCT
admet-2088	955	1	[	[	X
admet-2088	955	2	63	63	NUM
admet-2088	955	3	]	]	PUNCT
admet-2088	955	4	r.	r.	PROPN
admet-2088	955	5	parhi	parhi	NOUN
admet-2088	955	6	.	.	PUNCT
admet-2088	956	1	recent	recent	ADJ
admet-2088	956	2	advances	advance	NOUN
admet-2088	956	3	in	in	ADP
admet-2088	956	4	3d	3d	NUM
admet-2088	956	5	printed	print	VERB
admet-2088	956	6	microneedles	microneedle	NOUN
admet-2088	956	7	and	and	CCONJ
admet-2088	956	8	their	their	PRON
admet-2088	956	9	skin	skin	NOUN
admet-2088	956	10	delivery	delivery	NOUN
admet-2088	956	11	application	application	NOUN
admet-2088	956	12	in	in	ADP
admet-2088	956	13	the	the	DET
admet-2088	956	14	treatment	treatment	NOUN
admet-2088	956	15	of	of	ADP
admet-2088	956	16	various	various	ADJ
admet-2088	956	17	diseases	disease	NOUN
admet-2088	956	18	.	.	PUNCT
admet-2088	957	1	journal	journal	NOUN
admet-2088	957	2	of	of	ADP
admet-2088	957	3	drug	drug	NOUN
admet-2088	957	4	delivery	delivery	NOUN
admet-2088	957	5	science	science	NOUN
admet-2088	957	6	and	and	CCONJ
admet-2088	957	7	technology	technology	NOUN
admet-2088	957	8	84	84	NUM
admet-2088	957	9	(	(	PUNCT
admet-2088	957	10	2023	2023	NUM
admet-2088	957	11	)	)	PUNCT
admet-2088	957	12	104395	104395	NUM
admet-2088	957	13	.	.	PUNCT
admet-2088	958	1	https://doi.org/10.1016/j.jddst.2023.104395	https://doi.org/10.1016/j.jddst.2023.104395	PROPN
admet-2088	958	2	.	.	PUNCT
admet-2088	958	3	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	PRON
admet-2088	958	4	https://doi.org/10.1200/jco.2009.23.4799	https://doi.org/10.1200/jco.2009.23.4799	VERB
admet-2088	958	5	https://doi.org/10.1200/jco.2001.19.15.3477	https://doi.org/10.1200/jco.2001.19.15.3477	PROPN
admet-2088	958	6	https://doi.org/10.3390/jcm9020318	https://doi.org/10.3390/jcm9020318	NOUN
admet-2088	958	7	https://doi.org/10.3390/cancers12092494	https://doi.org/10.3390/cancers12092494	ADJ
admet-2088	958	8	https://doi.org/10.1200/edbk_199047	https://doi.org/10.1200/edbk_199047	ADJ
admet-2088	958	9	https://doi.org/10.1155/2015/841817	https://doi.org/10.1155/2015/841817	NOUN
admet-2088	958	10	https://doi.org/10.1093/rheumatology/kez308	https://doi.org/10.1093/rheumatology/kez308	NOUN
admet-2088	958	11	https://doi.org/10.1016/s0140-6736(14)60958-2	https://doi.org/10.1016/s0140-6736(14)60958-2	NOUN
admet-2088	958	12	https://doi.org/10.1200/jco.2013.53.0105	https://doi.org/10.1200/jco.2013.53.0105	NOUN
admet-2088	958	13	https://doi.org/10.1158/0008-5472.can-07-6614	https://doi.org/10.1158/0008-5472.can-07-6614	NUM
admet-2088	958	14	https://doi.org/10.1515/ntrev-2020-0117	https://doi.org/10.1515/ntrev-2020-0117	PROPN
admet-2088	958	15	https://doi.org/10.1016/j.canlet.2023.216148	https://doi.org/10.1016/j.canlet.2023.216148	PROPN
admet-2088	958	16	https://doi.org/10.3390/pharmaceutics13040575	https://doi.org/10.3390/pharmaceutics13040575	PROPN
admet-2088	958	17	https://doi.org/10.2147/ijn.s255874	https://doi.org/10.2147/ijn.s255874	PRON
admet-2088	959	1	https://doi.org/10.7573/2fdic.212281	https://doi.org/10.7573/2fdic.212281	PROPN
admet-2088	959	2	https://doi.org/10.1016/j.jddst.2023.104395	https://doi.org/10.1016/j.jddst.2023.104395	ADJ
admet-2088	959	3	m.	m.	NOUN
admet-2088	959	4	kulkarni	kulkarni	PROPN
admet-2088	959	5	et	et	PROPN
admet-2088	959	6	al	al	PROPN
admet-2088	959	7	.	.	PROPN
admet-2088	959	8	admet	admet	PROPN
admet-2088	959	9	&	&	CCONJ
admet-2088	959	10	dmpk	dmpk	PROPN
admet-2088	959	11	12(1	12(1	PROPN
admet-2088	959	12	)	)	PUNCT
admet-2088	959	13	(	(	PUNCT
admet-2088	959	14	2024	2024	NUM
admet-2088	959	15	)	)	PUNCT
admet-2088	959	16	107	107	NUM
admet-2088	959	17	-	-	SYM
admet-2088	959	18	150	150	NUM
admet-2088	959	19	140	140	NUM
admet-2088	959	20	[	[	X
admet-2088	959	21	64	64	NUM
admet-2088	959	22	]	]	PUNCT
admet-2088	959	23	x.	x.	NOUN
admet-2088	959	24	li	li	PROPN
admet-2088	959	25	,	,	PUNCT
admet-2088	959	26	z.	z.	PROPN
admet-2088	959	27	zhao	zhao	PROPN
admet-2088	959	28	,	,	PUNCT
admet-2088	959	29	m.	m.	PROPN
admet-2088	959	30	zhang	zhang	PROPN
admet-2088	959	31	,	,	PUNCT
admet-2088	959	32	g.	g.	PROPN
admet-2088	959	33	ling	ling	PROPN
admet-2088	959	34	,	,	PUNCT
admet-2088	959	35	p.	p.	PROPN
admet-2088	959	36	zhang	zhang	PROPN
admet-2088	959	37	,	,	PUNCT
admet-2088	959	38	research	research	NOUN
admet-2088	959	39	progress	progress	NOUN
admet-2088	959	40	of	of	ADP
admet-2088	959	41	microneedles	microneedle	NOUN
admet-2088	959	42	in	in	ADP
admet-2088	959	43	the	the	DET
admet-2088	959	44	treatment	treatment	NOUN
admet-2088	959	45	of	of	ADP
admet-2088	959	46	melanoma	melanoma	NOUN
admet-2088	959	47	.	.	PUNCT
admet-2088	960	1	journal	journal	PROPN
admet-2088	960	2	of	of	ADP
admet-2088	960	3	controlled	control	VERB
admet-2088	960	4	release	release	NOUN
admet-2088	960	5	348	348	NUM
admet-2088	960	6	(	(	PUNCT
admet-2088	960	7	2022	2022	NUM
admet-2088	960	8	)	)	PUNCT
admet-2088	960	9	631	631	NUM
admet-2088	960	10	-	-	SYM
admet-2088	960	11	647	647	NUM
admet-2088	960	12	.	.	PUNCT
admet-2088	961	1	https://doi.org/10.1016/j.jconrel.2022.06.021	https://doi.org/10.1016/j.jconrel.2022.06.021	NOUN
admet-2088	961	2	.	.	PUNCT
admet-2088	962	1	[	[	X
admet-2088	962	2	65	65	NUM
admet-2088	962	3	]	]	X
admet-2088	962	4	l.	l.	PROPN
admet-2088	962	5	bomar	bomar	PROPN
admet-2088	962	6	,	,	PUNCT
admet-2088	962	7	a.	a.	NOUN
admet-2088	962	8	senithilnathan	senithilnathan	PROPN
admet-2088	962	9	,	,	PUNCT
admet-2088	962	10	c.	c.	PROPN
admet-2088	962	11	ahn	ahn	PROPN
admet-2088	962	12	.	.	PUNCT
admet-2088	963	1	systemic	systemic	ADJ
admet-2088	963	2	therapies	therapy	NOUN
admet-2088	963	3	for	for	ADP
admet-2088	963	4	advanced	advanced	ADJ
admet-2088	963	5	melanoma	melanoma	NOUN
admet-2088	963	6	.	.	PUNCT
admet-2088	964	1	dermatologic	dermatologic	ADJ
admet-2088	964	2	clinics	clinic	NOUN
admet-2088	964	3	37	37	NUM
admet-2088	964	4	(	(	PUNCT
admet-2088	964	5	2019	2019	NUM
admet-2088	964	6	)	)	PUNCT
admet-2088	964	7	409	409	NUM
admet-2088	964	8	-	-	SYM
admet-2088	964	9	423	423	NUM
admet-2088	964	10	.	.	PUNCT
admet-2088	965	1	https://doi.org/10.1016/j.det.2019.05.001	https://doi.org/10.1016/j.det.2019.05.001	ADJ
admet-2088	965	2	.	.	PUNCT
admet-2088	966	1	[	[	X
admet-2088	966	2	66	66	NUM
admet-2088	966	3	]	]	PUNCT
admet-2088	966	4	c.v	c.v	PROPN
admet-2088	966	5	.	.	PROPN
admet-2088	966	6	pecot	pecot	PROPN
admet-2088	966	7	,	,	PUNCT
admet-2088	966	8	g.a	g.a	PROPN
admet-2088	966	9	.	.	PROPN
admet-2088	966	10	calin	calin	PROPN
admet-2088	966	11	,	,	PUNCT
admet-2088	966	12	r.l	r.l	PROPN
admet-2088	966	13	.	.	PROPN
admet-2088	966	14	coleman	coleman	PROPN
admet-2088	966	15	,	,	PUNCT
admet-2088	966	16	g.	g.	PROPN
admet-2088	966	17	lopez	lopez	PROPN
admet-2088	966	18	-	-	PUNCT
admet-2088	966	19	berestein	berestein	PROPN
admet-2088	966	20	,	,	PUNCT
admet-2088	966	21	a.k	a.k	PROPN
admet-2088	966	22	.	.	PROPN
admet-2088	966	23	sood	sood	PROPN
admet-2088	966	24	,	,	PUNCT
admet-2088	966	25	rna	rna	NOUN
admet-2088	966	26	interference	interference	NOUN
admet-2088	966	27	in	in	ADP
admet-2088	966	28	the	the	DET
admet-2088	966	29	clinic	clinic	NOUN
admet-2088	966	30	:	:	PUNCT
admet-2088	966	31	challenges	challenge	NOUN
admet-2088	966	32	and	and	CCONJ
admet-2088	966	33	future	future	ADJ
admet-2088	966	34	directions	direction	NOUN
admet-2088	966	35	.	.	PUNCT
admet-2088	967	1	nature	nature	NOUN
admet-2088	967	2	reviews	review	VERB
admet-2088	967	3	cancer	cancer	NOUN
admet-2088	967	4	11	11	NUM
admet-2088	967	5	(	(	PUNCT
admet-2088	967	6	2011	2011	NUM
admet-2088	967	7	)	)	PUNCT
admet-2088	967	8	59	59	NUM
admet-2088	967	9	-	-	SYM
admet-2088	967	10	67	67	NUM
admet-2088	967	11	.	.	PUNCT
admet-2088	968	1	https://doi.org/10.1038/nrc2966	https://doi.org/10.1038/nrc2966	X
admet-2088	968	2	.	.	PUNCT
admet-2088	969	1	[	[	X
admet-2088	969	2	67	67	NUM
admet-2088	969	3	]	]	PUNCT
admet-2088	969	4	z.	z.	PROPN
admet-2088	969	5	khorsandi	khorsandi	PROPN
admet-2088	969	6	,	,	PUNCT
admet-2088	969	7	m.	m.	NOUN
admet-2088	969	8	borjian	borjian	PROPN
admet-2088	969	9	-	-	PUNCT
admet-2088	969	10	boroujeni	boroujeni	PROPN
admet-2088	969	11	,	,	PUNCT
admet-2088	969	12	r.	r.	PROPN
admet-2088	969	13	yekani	yekani	PROPN
admet-2088	969	14	,	,	PUNCT
admet-2088	969	15	r.s	r.s	PROPN
admet-2088	969	16	.	.	PROPN
admet-2088	969	17	varma	varma	PROPN
admet-2088	969	18	.	.	PUNCT
admet-2088	970	1	carbon	carbon	NOUN
admet-2088	970	2	nanomaterials	nanomaterial	NOUN
admet-2088	970	3	with	with	ADP
admet-2088	970	4	chitosan	chitosan	NOUN
admet-2088	970	5	:	:	PUNCT
admet-2088	970	6	a	a	DET
admet-2088	970	7	winning	win	VERB
admet-2088	970	8	combination	combination	NOUN
admet-2088	970	9	for	for	ADP
admet-2088	970	10	drug	drug	NOUN
admet-2088	970	11	delivery	delivery	NOUN
admet-2088	970	12	systems	system	NOUN
admet-2088	970	13	.	.	PUNCT
admet-2088	971	1	journal	journal	NOUN
admet-2088	971	2	of	of	ADP
admet-2088	971	3	drug	drug	NOUN
admet-2088	971	4	delivery	delivery	NOUN
admet-2088	971	5	science	science	NOUN
admet-2088	971	6	and	and	CCONJ
admet-2088	971	7	technology	technology	NOUN
admet-2088	971	8	66	66	NUM
admet-2088	971	9	(	(	PUNCT
admet-2088	971	10	2021	2021	NUM
admet-2088	971	11	)	)	PUNCT
admet-2088	971	12	102847	102847	NUM
admet-2088	971	13	.	.	PUNCT
admet-2088	972	1	https://doi.org/10.1016/j.jddst.2021.102847	https://doi.org/10.1016/j.jddst.2021.102847	PROPN
admet-2088	972	2	.	.	PUNCT
admet-2088	973	1	[	[	X
admet-2088	973	2	68	68	NUM
admet-2088	973	3	]	]	X
admet-2088	973	4	w.	w.	PROPN
admet-2088	973	5	gong	gong	PROPN
admet-2088	973	6	,	,	PUNCT
admet-2088	973	7	t.	t.	PROPN
admet-2088	973	8	zhang	zhang	PROPN
admet-2088	973	9	,	,	PUNCT
admet-2088	973	10	m.	m.	NOUN
admet-2088	973	11	che	che	PROPN
admet-2088	973	12	,	,	PUNCT
admet-2088	973	13	y.	y.	PROPN
admet-2088	973	14	wang	wang	PROPN
admet-2088	973	15	,	,	PUNCT
admet-2088	973	16	c.	c.	PROPN
admet-2088	973	17	he	he	PROPN
admet-2088	973	18	,	,	PUNCT
admet-2088	973	19	l.	l.	PROPN
admet-2088	973	20	liu	liu	PROPN
admet-2088	973	21	,	,	PUNCT
admet-2088	973	22	z.	z.	PROPN
admet-2088	973	23	lv	lv	PROPN
admet-2088	973	24	,	,	PUNCT
admet-2088	973	25	c.	c.	PROPN
admet-2088	973	26	xiao	xiao	PROPN
admet-2088	973	27	,	,	PUNCT
admet-2088	973	28	h.	h.	PROPN
admet-2088	973	29	wang	wang	PROPN
admet-2088	973	30	,	,	PUNCT
admet-2088	973	31	s.	s.	PROPN
admet-2088	973	32	zhang	zhang	PROPN
admet-2088	973	33	.	.	PUNCT
admet-2088	974	1	recent	recent	ADJ
admet-2088	974	2	advances	advance	NOUN
admet-2088	974	3	in	in	ADP
admet-2088	974	4	nanomaterials	nanomaterial	NOUN
admet-2088	974	5	for	for	ADP
admet-2088	974	6	the	the	DET
admet-2088	974	7	treatment	treatment	NOUN
admet-2088	974	8	of	of	ADP
admet-2088	974	9	spinal	spinal	ADJ
admet-2088	974	10	cord	cord	NOUN
admet-2088	974	11	injury	injury	NOUN
admet-2088	974	12	.	.	PUNCT
admet-2088	975	1	materials	material	NOUN
admet-2088	975	2	today	today	NOUN
admet-2088	975	3	bio	bio	PROPN
admet-2088	975	4	18	18	NUM
admet-2088	975	5	(	(	PUNCT
admet-2088	975	6	2023	2023	NUM
admet-2088	975	7	)	)	PUNCT
admet-2088	975	8	100524	100524	NUM
admet-2088	975	9	.	.	PUNCT
admet-2088	976	1	https://doi.org/10.1016/j.mtbio.2022.100524	https://doi.org/10.1016/j.mtbio.2022.100524	ADJ
admet-2088	976	2	.	.	PUNCT
admet-2088	977	1	[	[	X
admet-2088	977	2	69	69	NUM
admet-2088	977	3	]	]	X
admet-2088	977	4	m.m	m.m	PROPN
admet-2088	977	5	.	.	PROPN
admet-2088	977	6	el	el	PROPN
admet-2088	977	7	-	-	PUNCT
admet-2088	977	8	kady	kady	PROPN
admet-2088	977	9	,	,	PUNCT
admet-2088	977	10	i.	i.	PROPN
admet-2088	977	11	ansari	ansari	PROPN
admet-2088	977	12	,	,	PUNCT
admet-2088	977	13	c.	c.	PROPN
admet-2088	977	14	arora	arora	PROPN
admet-2088	977	15	,	,	PUNCT
admet-2088	977	16	n.	n.	PROPN
admet-2088	977	17	rai	rai	PROPN
admet-2088	977	18	,	,	PUNCT
admet-2088	977	19	s.	s.	PROPN
admet-2088	977	20	soni	soni	PROPN
admet-2088	977	21	,	,	PUNCT
admet-2088	977	22	d.k	d.k	PROPN
admet-2088	977	23	.	.	PROPN
admet-2088	977	24	verma	verma	PROPN
admet-2088	977	25	,	,	PUNCT
admet-2088	977	26	p.	p.	PROPN
admet-2088	977	27	singh	singh	PROPN
admet-2088	977	28	,	,	PUNCT
admet-2088	977	29	a.	a.	PROPN
admet-2088	977	30	el	el	PROPN
admet-2088	977	31	din	din	PROPN
admet-2088	977	32	mahmoud	mahmoud	PROPN
admet-2088	977	33	.	.	PUNCT
admet-2088	978	1	nanomaterials	nanomaterial	NOUN
admet-2088	978	2	:	:	PUNCT
admet-2088	978	3	a	a	DET
admet-2088	978	4	comprehensive	comprehensive	ADJ
admet-2088	978	5	review	review	NOUN
admet-2088	978	6	of	of	ADP
admet-2088	978	7	applications	application	NOUN
admet-2088	978	8	,	,	PUNCT
admet-2088	978	9	toxicity	toxicity	NOUN
admet-2088	978	10	,	,	PUNCT
admet-2088	978	11	impact	impact	NOUN
admet-2088	978	12	,	,	PUNCT
admet-2088	978	13	and	and	CCONJ
admet-2088	978	14	fate	fate	VERB
admet-2088	978	15	to	to	ADP
admet-2088	978	16	environment	environment	NOUN
admet-2088	978	17	.	.	PUNCT
admet-2088	979	1	journal	journal	NOUN
admet-2088	979	2	of	of	ADP
admet-2088	979	3	molecular	molecular	ADJ
admet-2088	979	4	liquids	liquid	NOUN
admet-2088	979	5	370	370	NUM
admet-2088	979	6	(	(	PUNCT
admet-2088	979	7	2023	2023	NUM
admet-2088	979	8	)	)	PUNCT
admet-2088	979	9	121046	121046	NUM
admet-2088	979	10	.	.	PUNCT
admet-2088	980	1	https://doi.org/10.1016/j.molliq.2022.121046	https://doi.org/10.1016/j.molliq.2022.121046	NOUN
admet-2088	980	2	.	.	PUNCT
admet-2088	981	1	[	[	X
admet-2088	981	2	70	70	X
admet-2088	981	3	]	]	PUNCT
admet-2088	981	4	j.	j.	PROPN
admet-2088	981	5	seaberg	seaberg	PROPN
admet-2088	981	6	,	,	PUNCT
admet-2088	981	7	j.r	j.r	PROPN
admet-2088	981	8	.	.	PROPN
admet-2088	981	9	clegg	clegg	PROPN
admet-2088	981	10	,	,	PUNCT
admet-2088	981	11	r.	r.	PROPN
admet-2088	981	12	bhattacharya	bhattacharya	PROPN
admet-2088	981	13	,	,	PUNCT
admet-2088	981	14	p.	p.	PROPN
admet-2088	981	15	mukherjee	mukherjee	PROPN
admet-2088	981	16	.	.	PUNCT
admet-2088	982	1	self	self	NOUN
admet-2088	982	2	-	-	PUNCT
admet-2088	982	3	therapeutic	therapeutic	ADJ
admet-2088	982	4	nanomaterials	nanomaterial	NOUN
admet-2088	982	5	:	:	PUNCT
admet-2088	982	6	applications	application	NOUN
admet-2088	982	7	in	in	ADP
admet-2088	982	8	biology	biology	NOUN
admet-2088	982	9	and	and	CCONJ
admet-2088	982	10	medicine	medicine	NOUN
admet-2088	982	11	.	.	PUNCT
admet-2088	983	1	materials	material	NOUN
admet-2088	983	2	today	today	NOUN
admet-2088	983	3	62	62	NUM
admet-2088	983	4	(	(	PUNCT
admet-2088	983	5	2023	2023	NUM
admet-2088	983	6	)	)	PUNCT
admet-2088	983	7	190	190	NUM
admet-2088	983	8	-	-	SYM
admet-2088	983	9	224	224	NUM
admet-2088	983	10	.	.	PUNCT
admet-2088	984	1	https://doi.org/10.1016/j.mattod.2022.11.007	https://doi.org/10.1016/j.mattod.2022.11.007	PROPN
admet-2088	984	2	.	.	PUNCT
admet-2088	985	1	[	[	X
admet-2088	985	2	71	71	NUM
admet-2088	985	3	]	]	X
admet-2088	985	4	m.	m.	NOUN
admet-2088	985	5	liong	liong	PROPN
admet-2088	985	6	,	,	PUNCT
admet-2088	985	7	j.	j.	PROPN
admet-2088	985	8	lu	lu	PROPN
admet-2088	985	9	,	,	PUNCT
admet-2088	985	10	m.	m.	NOUN
admet-2088	985	11	kovochich	kovochich	PROPN
admet-2088	985	12	,	,	PUNCT
admet-2088	985	13	t.	t.	PROPN
admet-2088	985	14	xia	xia	PROPN
admet-2088	985	15	,	,	PUNCT
admet-2088	985	16	s.g	s.g	PROPN
admet-2088	985	17	.	.	PROPN
admet-2088	985	18	ruehm	ruehm	PROPN
admet-2088	985	19	,	,	PUNCT
admet-2088	985	20	a.e	a.e	PROPN
admet-2088	985	21	.	.	PROPN
admet-2088	985	22	nel	nel	PROPN
admet-2088	985	23	,	,	PUNCT
admet-2088	985	24	f.	f.	PROPN
admet-2088	985	25	tamanoi	tamanoi	PROPN
admet-2088	985	26	,	,	PUNCT
admet-2088	985	27	j.i	j.i	PROPN
admet-2088	985	28	.	.	PROPN
admet-2088	985	29	zink	zink	NOUN
admet-2088	985	30	.	.	PUNCT
admet-2088	986	1	multifunctional	multifunctional	ADJ
admet-2088	986	2	inorganic	inorganic	ADJ
admet-2088	986	3	nanoparticles	nanoparticle	NOUN
admet-2088	986	4	for	for	ADP
admet-2088	986	5	imaging	imaging	NOUN
admet-2088	986	6	,	,	PUNCT
admet-2088	986	7	targeting	targeting	NOUN
admet-2088	986	8	,	,	PUNCT
admet-2088	986	9	and	and	CCONJ
admet-2088	986	10	drug	drug	NOUN
admet-2088	986	11	delivery	delivery	NOUN
admet-2088	986	12	.	.	PUNCT
admet-2088	987	1	acs	acs	PROPN
admet-2088	987	2	nano	nano	VERB
admet-2088	987	3	2	2	NUM
admet-2088	987	4	(	(	PUNCT
admet-2088	987	5	2008	2008	NUM
admet-2088	987	6	)	)	PUNCT
admet-2088	987	7	889	889	NUM
admet-2088	987	8	-	-	SYM
admet-2088	987	9	896	896	NUM
admet-2088	987	10	.	.	PUNCT
admet-2088	988	1	https://doi.org/10.1021/nn800072	https://doi.org/10.1021/nn800072	X
admet-2088	988	2	t.	t.	X
admet-2088	989	1	[	[	X
admet-2088	989	2	72	72	NUM
admet-2088	989	3	]	]	PUNCT
admet-2088	989	4	s.	s.	PROPN
admet-2088	989	5	hassan	hassan	PROPN
admet-2088	989	6	,	,	PUNCT
admet-2088	989	7	g.	g.	PROPN
admet-2088	989	8	prakash	prakash	PROPN
admet-2088	989	9	,	,	PUNCT
admet-2088	989	10	a.b	a.b	PROPN
admet-2088	989	11	.	.	PROPN
admet-2088	989	12	ozturk	ozturk	PROPN
admet-2088	989	13	,	,	PUNCT
admet-2088	989	14	s.	s.	PROPN
admet-2088	989	15	saghazadeh	saghazadeh	PROPN
admet-2088	989	16	,	,	PUNCT
admet-2088	989	17	md.f	md.f	PROPN
admet-2088	989	18	.	.	PUNCT
admet-2088	989	19	sohail	sohail	PROPN
admet-2088	989	20	,	,	PUNCT
admet-2088	989	21	j.	j.	PROPN
admet-2088	989	22	seo	seo	PROPN
admet-2088	989	23	,	,	PUNCT
admet-2088	989	24	m.r	m.r	PROPN
admet-2088	989	25	.	.	PROPN
admet-2088	989	26	dokmeci	dokmeci	PROPN
admet-2088	989	27	,	,	PUNCT
admet-2088	989	28	y.s	y.s	PROPN
admet-2088	989	29	.	.	PROPN
admet-2088	989	30	zhang	zhang	PROPN
admet-2088	989	31	,	,	PUNCT
admet-2088	989	32	a.	a.	NOUN
admet-2088	989	33	khademhosseini	khademhosseini	PROPN
admet-2088	989	34	.	.	PUNCT
admet-2088	990	1	evolution	evolution	NOUN
admet-2088	990	2	and	and	CCONJ
admet-2088	990	3	clinical	clinical	ADJ
admet-2088	990	4	translation	translation	NOUN
admet-2088	990	5	of	of	ADP
admet-2088	990	6	drug	drug	NOUN
admet-2088	990	7	delivery	delivery	NOUN
admet-2088	990	8	nanomaterials	nanomaterial	NOUN
admet-2088	990	9	.	.	PUNCT
admet-2088	991	1	nano	nano	NOUN
admet-2088	991	2	today	today	NOUN
admet-2088	991	3	15	15	NUM
admet-2088	991	4	(	(	PUNCT
admet-2088	991	5	2017	2017	NUM
admet-2088	991	6	)	)	PUNCT
admet-2088	991	7	91	91	NUM
admet-2088	991	8	-	-	SYM
admet-2088	991	9	106	106	NUM
admet-2088	991	10	.	.	PUNCT
admet-2088	992	1	https://doi.org/10.1016/j.nantod.2017.06.008	https://doi.org/10.1016/j.nantod.2017.06.008	NOUN
admet-2088	992	2	.	.	PUNCT
admet-2088	993	1	[	[	X
admet-2088	993	2	73	73	NUM
admet-2088	993	3	]	]	PUNCT
admet-2088	993	4	m.	m.	NOUN
admet-2088	993	5	faraday	faraday	PROPN
admet-2088	993	6	.	.	PUNCT
admet-2088	994	1	x.	x.	PROPN
admet-2088	995	1	the	the	DET
admet-2088	995	2	bakerian	bakerian	ADJ
admet-2088	995	3	lecture	lecture	NOUN
admet-2088	995	4	-	-	PUNCT
admet-2088	995	5	experimental	experimental	ADJ
admet-2088	995	6	relations	relation	NOUN
admet-2088	995	7	of	of	ADP
admet-2088	995	8	gold	gold	NOUN
admet-2088	995	9	(	(	PUNCT
admet-2088	995	10	and	and	CCONJ
admet-2088	995	11	other	other	ADJ
admet-2088	995	12	metals	metal	NOUN
admet-2088	995	13	)	)	PUNCT
admet-2088	995	14	to	to	ADP
admet-2088	995	15	light	light	ADJ
admet-2088	995	16	,	,	PUNCT
admet-2088	995	17	philosophical	philosophical	ADJ
admet-2088	995	18	transactions	transaction	NOUN
admet-2088	995	19	.	.	PUNCT
admet-2088	996	1	royal	royal	ADJ
admet-2088	996	2	society	society	PROPN
admet-2088	996	3	,	,	PUNCT
admet-2088	996	4	london	london	PROPN
admet-2088	996	5	,	,	PUNCT
admet-2088	996	6	147	147	NUM
admet-2088	996	7	(	(	PUNCT
admet-2088	996	8	1997	1997	NUM
admet-2088	996	9	)	)	PUNCT
admet-2088	996	10	145	145	NUM
admet-2088	996	11	-	-	SYM
admet-2088	996	12	181	181	NUM
admet-2088	996	13	.	.	PUNCT
admet-2088	997	1	https://doi.org/10.1098/rstl.1857.0011	https://doi.org/10.1098/rstl.1857.0011	PROPN
admet-2088	997	2	.	.	PUNCT
admet-2088	998	1	[	[	X
admet-2088	998	2	74	74	NUM
admet-2088	998	3	]	]	X
admet-2088	998	4	a.s	a.s	PROPN
admet-2088	998	5	.	.	PROPN
admet-2088	998	6	thakor	thakor	PROPN
admet-2088	998	7	,	,	PUNCT
admet-2088	998	8	j.	j.	PROPN
admet-2088	998	9	jokerst	jokerst	PROPN
admet-2088	998	10	,	,	PUNCT
admet-2088	998	11	c.	c.	PROPN
admet-2088	998	12	zavaleta	zavaleta	PROPN
admet-2088	998	13	,	,	PUNCT
admet-2088	998	14	t.f	t.f	PROPN
admet-2088	998	15	.	.	PROPN
admet-2088	998	16	massoud	massoud	PROPN
admet-2088	998	17	,	,	PUNCT
admet-2088	998	18	s.s	s.s	PROPN
admet-2088	998	19	.	.	PROPN
admet-2088	998	20	gambhir	gambhir	PROPN
admet-2088	998	21	.	.	PUNCT
admet-2088	999	1	gold	gold	NOUN
admet-2088	999	2	nanoparticles	nanoparticle	NOUN
admet-2088	999	3	:	:	PUNCT
admet-2088	999	4	a	a	DET
admet-2088	999	5	revival	revival	NOUN
admet-2088	999	6	in	in	ADP
admet-2088	999	7	precious	precious	ADJ
admet-2088	999	8	metal	metal	NOUN
admet-2088	999	9	administration	administration	NOUN
admet-2088	999	10	to	to	ADP
admet-2088	999	11	patients	patient	NOUN
admet-2088	999	12	.	.	PUNCT
admet-2088	1000	1	nano	nano	NOUN
admet-2088	1000	2	letters	letter	NOUN
admet-2088	1000	3	11	11	NUM
admet-2088	1000	4	(	(	PUNCT
admet-2088	1000	5	2011	2011	NUM
admet-2088	1000	6	)	)	PUNCT
admet-2088	1000	7	4029	4029	NUM
admet-2088	1000	8	-	-	SYM
admet-2088	1000	9	4036	4036	NUM
admet-2088	1000	10	.	.	PUNCT
admet-2088	1001	1	https://doi.org/10.1021/nl202559p	https://doi.org/10.1021/nl202559p	PROPN
admet-2088	1001	2	.	.	PUNCT
admet-2088	1002	1	[	[	X
admet-2088	1002	2	75	75	NUM
admet-2088	1002	3	]	]	X
admet-2088	1002	4	y.	y.	PROPN
admet-2088	1002	5	qu	qu	PROPN
admet-2088	1002	6	,	,	PUNCT
admet-2088	1002	7	s.	s.	PROPN
admet-2088	1002	8	lian	lian	PROPN
admet-2088	1002	9	,	,	PUNCT
admet-2088	1002	10	w.	w.	PROPN
admet-2088	1002	11	shen	shen	PROPN
admet-2088	1002	12	,	,	PUNCT
admet-2088	1002	13	z.	z.	PROPN
admet-2088	1002	14	li	li	PROPN
admet-2088	1002	15	,	,	PUNCT
admet-2088	1002	16	j.	j.	PROPN
admet-2088	1002	17	yang	yang	PROPN
admet-2088	1002	18	,	,	PUNCT
admet-2088	1002	19	h.	h.	PROPN
admet-2088	1002	20	zhang	zhang	PROPN
admet-2088	1002	21	.	.	PUNCT
admet-2088	1003	1	rod	rod	NOUN
admet-2088	1003	2	-	-	PUNCT
admet-2088	1003	3	shaped	shape	VERB
admet-2088	1003	4	gold	gold	NOUN
admet-2088	1003	5	nanoparticles	nanoparticle	NOUN
admet-2088	1003	6	biosynthesized	biosynthesize	VERB
admet-2088	1003	7	using	use	VERB
admet-2088	1004	1	pb2	pb2	PROPN
admet-2088	1004	2	+	+	ADJ
admet-2088	1004	3	-induced	-induced	ADJ
admet-2088	1004	4	fungus	fungus	ADJ
admet-2088	1004	5	aspergillus	aspergillus	NOUN
admet-2088	1004	6	sp.wlau	sp.wlau	NOUN
admet-2088	1004	7	.	.	PUNCT
admet-2088	1005	1	bioprocess	bioprocess	NOUN
admet-2088	1005	2	and	and	CCONJ
admet-2088	1005	3	biosystems	biosystems	PROPN
admet-2088	1005	4	engineering	engineer	VERB
admet-2088	1005	5	43	43	NUM
admet-2088	1005	6	(	(	PUNCT
admet-2088	1005	7	2020	2020	NUM
admet-2088	1005	8	)	)	PUNCT
admet-2088	1005	9	123131	123131	NUM
admet-2088	1005	10	.	.	PUNCT
admet-2088	1006	1	https://doi.org/10.1007/s00449-019-02210-w	https://doi.org/10.1007/s00449-019-02210-w	PROPN
admet-2088	1006	2	.	.	PUNCT
admet-2088	1007	1	[	[	X
admet-2088	1007	2	76	76	NUM
admet-2088	1007	3	]	]	X
admet-2088	1007	4	e.c	e.c	PROPN
admet-2088	1007	5	.	.	PROPN
admet-2088	1007	6	dreaden	dreaden	PROPN
admet-2088	1007	7	,	,	PUNCT
admet-2088	1007	8	l.a	l.a	PROPN
admet-2088	1007	9	.	.	PROPN
admet-2088	1007	10	austin	austin	PROPN
admet-2088	1007	11	,	,	PUNCT
admet-2088	1007	12	m.a	m.a	PROPN
admet-2088	1007	13	.	.	PROPN
admet-2088	1007	14	mackey	mackey	PROPN
admet-2088	1007	15	,	,	PUNCT
admet-2088	1007	16	m.a	m.a	PROPN
admet-2088	1007	17	.	.	PROPN
admet-2088	1007	18	el	el	PROPN
admet-2088	1007	19	-	-	PUNCT
admet-2088	1007	20	sayed	say	VERB
admet-2088	1007	21	.	.	PUNCT
admet-2088	1007	22	size	size	NOUN
admet-2088	1007	23	matters	matter	NOUN
admet-2088	1007	24	:	:	PUNCT
admet-2088	1007	25	gold	gold	NOUN
admet-2088	1007	26	nanoparticles	nanoparticle	NOUN
admet-2088	1007	27	in	in	ADP
admet-2088	1007	28	targeted	target	VERB
admet-2088	1007	29	cancer	cancer	NOUN
admet-2088	1007	30	drug	drug	NOUN
admet-2088	1007	31	delivery	delivery	NOUN
admet-2088	1007	32	.	.	PUNCT
admet-2088	1008	1	therapeutic	therapeutic	ADJ
admet-2088	1008	2	delivery	delivery	NOUN
admet-2088	1008	3	.	.	PUNCT
admet-2088	1009	1	3	3	NUM
admet-2088	1009	2	(	(	PUNCT
admet-2088	1009	3	2012	2012	NUM
admet-2088	1009	4	)	)	PUNCT
admet-2088	1009	5	457	457	NUM
admet-2088	1009	6	-	-	SYM
admet-2088	1009	7	478	478	NUM
admet-2088	1009	8	.	.	PUNCT
admet-2088	1010	1	https://doi.org/10.4155/tde.12.21	https://doi.org/10.4155/tde.12.21	PROPN
admet-2088	1010	2	.	.	PUNCT
admet-2088	1011	1	[	[	X
admet-2088	1011	2	77	77	X
admet-2088	1011	3	]	]	X
admet-2088	1011	4	y.	y.	PROPN
admet-2088	1011	5	jeong	jeong	PROPN
admet-2088	1011	6	,	,	PUNCT
admet-2088	1011	7	g.	g.	PROPN
admet-2088	1011	8	kim	kim	PROPN
admet-2088	1011	9	,	,	PUNCT
admet-2088	1011	10	s.	s.	PROPN
admet-2088	1011	11	jeong	jeong	PROPN
admet-2088	1011	12	,	,	PUNCT
admet-2088	1011	13	b.	b.	PROPN
admet-2088	1011	14	lee	lee	PROPN
admet-2088	1011	15	,	,	PUNCT
admet-2088	1011	16	s.	s.	PROPN
admet-2088	1011	17	kim	kim	PROPN
admet-2088	1011	18	,	,	PUNCT
admet-2088	1011	19	w.-g	w.-g	PROPN
admet-2088	1011	20	.	.	PUNCT
admet-2088	1012	1	koh	koh	PROPN
admet-2088	1012	2	,	,	PUNCT
admet-2088	1012	3	k.	k.	PROPN
admet-2088	1012	4	lee	lee	PROPN
admet-2088	1012	5	.	.	PUNCT
admet-2088	1013	1	cancer	cancer	PROPN
admet-2088	1013	2	selective	selective	ADJ
admet-2088	1013	3	turn	turn	NOUN
admet-2088	1013	4	-	-	PUNCT
admet-2088	1013	5	on	on	ADP
admet-2088	1013	6	fluorescence	fluorescence	NOUN
admet-2088	1013	7	imaging	imaging	NOUN
admet-2088	1013	8	using	use	VERB
admet-2088	1013	9	a	a	DET
admet-2088	1013	10	biopolymeric	biopolymeric	ADJ
admet-2088	1013	11	nanocarrier	nanocarrier	NOUN
admet-2088	1013	12	.	.	PUNCT
admet-2088	1014	1	biomacromolecules	biomacromolecule	NOUN
admet-2088	1014	2	20(span	20(span	NUM
admet-2088	1014	3	80	80	NUM
admet-2088	1014	4	)	)	PUNCT
admet-2088	1014	5	(	(	PUNCT
admet-2088	1014	6	2019	2019	NUM
admet-2088	1014	7	)	)	PUNCT
admet-2088	1014	8	1068	1068	NUM
admet-2088	1014	9	-	-	SYM
admet-2088	1014	10	1076	1076	NUM
admet-2088	1014	11	.	.	PUNCT
admet-2088	1015	1	https://doi.org/10.1021/acs.biomac.8b01690	https://doi.org/10.1021/acs.biomac.8b01690	X
admet-2088	1015	2	.	.	PUNCT
admet-2088	1016	1	[	[	X
admet-2088	1016	2	78	78	NUM
admet-2088	1016	3	]	]	X
admet-2088	1016	4	s.k	s.k	PROPN
admet-2088	1016	5	.	.	PROPN
admet-2088	1016	6	vemuri	vemuri	PROPN
admet-2088	1016	7	,	,	PUNCT
admet-2088	1016	8	r.r	r.r	PROPN
admet-2088	1016	9	.	.	PROPN
admet-2088	1016	10	banala	banala	PROPN
admet-2088	1016	11	,	,	PUNCT
admet-2088	1016	12	s.	s.	PROPN
admet-2088	1016	13	mukherjee	mukherjee	PROPN
admet-2088	1016	14	,	,	PUNCT
admet-2088	1016	15	p.	p.	PROPN
admet-2088	1016	16	uppula	uppula	PROPN
admet-2088	1016	17	,	,	PUNCT
admet-2088	1016	18	g.p.v	g.p.v	NOUN
admet-2088	1016	19	.	.	PUNCT
admet-2088	1017	1	subbaiah	subbaiah	PROPN
admet-2088	1017	2	,	,	PUNCT
admet-2088	1018	1	a.v.g	a.v.g	NOUN
admet-2088	1018	2	.	.	PUNCT
admet-2088	1018	3	reddy	reddy	PROPN
admet-2088	1018	4	,	,	PUNCT
admet-2088	1018	5	t.	t.	PROPN
admet-2088	1018	6	malarvilli	malarvilli	PROPN
admet-2088	1018	7	.	.	PUNCT
admet-2088	1019	1	novel	novel	PROPN
admet-2088	1019	2	biosynthesized	biosynthesize	VERB
admet-2088	1019	3	gold	gold	NOUN
admet-2088	1019	4	nanoparticles	nanoparticle	NOUN
admet-2088	1019	5	as	as	ADP
admet-2088	1019	6	anti	anti	ADJ
admet-2088	1019	7	-	-	ADJ
admet-2088	1019	8	cancer	cancer	ADJ
admet-2088	1019	9	agents	agent	NOUN
admet-2088	1019	10	against	against	ADP
admet-2088	1019	11	breast	breast	NOUN
admet-2088	1019	12	cancer	cancer	NOUN
admet-2088	1019	13	:	:	PUNCT
admet-2088	1019	14	synthesis	synthesis	NOUN
admet-2088	1019	15	,	,	PUNCT
admet-2088	1019	16	biological	biological	ADJ
admet-2088	1019	17	evaluation	evaluation	NOUN
admet-2088	1019	18	,	,	PUNCT
admet-2088	1019	19	molecular	molecular	ADJ
admet-2088	1019	20	modelling	modelling	NOUN
admet-2088	1019	21	studies	study	NOUN
admet-2088	1019	22	.	.	PUNCT
admet-2088	1020	1	material	material	NOUN
admet-2088	1020	2	science	science	NOUN
admet-2088	1020	3	and	and	CCONJ
admet-2088	1020	4	engineering	engineering	NOUN
admet-2088	1020	5	c	c	PROPN
admet-2088	1020	6	99	99	NUM
admet-2088	1020	7	(	(	PUNCT
admet-2088	1020	8	2019	2019	NUM
admet-2088	1020	9	)	)	PUNCT
admet-2088	1020	10	417	417	NUM
admet-2088	1020	11	-	-	SYM
admet-2088	1020	12	429	429	NUM
admet-2088	1020	13	.	.	PUNCT
admet-2088	1021	1	https://doi.org/10.1016/j.msec.2019.01.123	https://doi.org/10.1016/j.msec.2019.01.123	NOUN
admet-2088	1021	2	.	.	PUNCT
admet-2088	1022	1	[	[	X
admet-2088	1022	2	79	79	NUM
admet-2088	1022	3	]	]	PUNCT
admet-2088	1022	4	k.	k.	PROPN
admet-2088	1022	5	vyas	vyas	PROPN
admet-2088	1022	6	,	,	PUNCT
admet-2088	1022	7	m.	m.	NOUN
admet-2088	1022	8	rathod	rathod	PROPN
admet-2088	1022	9	,	,	PUNCT
admet-2088	1022	10	m.m	m.m	PROPN
admet-2088	1022	11	.	.	PROPN
admet-2088	1022	12	patel	patel	PROPN
admet-2088	1022	13	.	.	PUNCT
admet-2088	1023	1	insight	insight	NOUN
admet-2088	1023	2	on	on	ADP
admet-2088	1023	3	nano	nano	NOUN
admet-2088	1023	4	drug	drug	NOUN
admet-2088	1023	5	delivery	delivery	NOUN
admet-2088	1023	6	systems	system	NOUN
admet-2088	1023	7	with	with	ADP
admet-2088	1023	8	targeted	target	VERB
admet-2088	1023	9	therapy	therapy	NOUN
admet-2088	1023	10	in	in	ADP
admet-2088	1023	11	treatment	treatment	NOUN
admet-2088	1023	12	of	of	ADP
admet-2088	1023	13	oral	oral	ADJ
admet-2088	1023	14	cancer	cancer	NOUN
admet-2088	1023	15	.	.	PUNCT
admet-2088	1024	1	nanomedicine	nanomedicine	NOUN
admet-2088	1024	2	:	:	PUNCT
admet-2088	1024	3	nanotechnology	nanotechnology	NOUN
admet-2088	1024	4	,	,	PUNCT
admet-2088	1024	5	biology	biology	NOUN
admet-2088	1024	6	,	,	PUNCT
admet-2088	1024	7	and	and	CCONJ
admet-2088	1024	8	medicine	medicine	NOUN
admet-2088	1024	9	49	49	NUM
admet-2088	1024	10	(	(	PUNCT
admet-2088	1024	11	2023	2023	NUM
admet-2088	1024	12	)	)	PUNCT
admet-2088	1024	13	102662	102662	NUM
admet-2088	1024	14	.	.	PUNCT
admet-2088	1025	1	https://doi.org/10.1016/j.nano.2023.102662	https://doi.org/10.1016/j.nano.2023.102662	NOUN
admet-2088	1025	2	.	.	PUNCT
admet-2088	1026	1	[	[	X
admet-2088	1026	2	80	80	NUM
admet-2088	1026	3	]	]	PUNCT
admet-2088	1026	4	a.	a.	NOUN
admet-2088	1026	5	latorre	latorre	NOUN
admet-2088	1026	6	,	,	PUNCT
admet-2088	1026	7	a.	a.	NOUN
admet-2088	1026	8	latorre	latorre	NOUN
admet-2088	1026	9	,	,	PUNCT
admet-2088	1026	10	m.	m.	NOUN
admet-2088	1026	11	castellanos	castellanos	PROPN
admet-2088	1026	12	,	,	PUNCT
admet-2088	1026	13	n.	n.	PROPN
admet-2088	1026	14	lafuente	lafuente	PROPN
admet-2088	1026	15	-	-	PUNCT
admet-2088	1026	16	gómez	gómez	NOUN
admet-2088	1026	17	,	,	PUNCT
admet-2088	1026	18	c.r	c.r	PROPN
admet-2088	1026	19	.	.	PROPN
admet-2088	1026	20	diaz	diaz	PROPN
admet-2088	1026	21	,	,	PUNCT
admet-2088	1026	22	a.	a.	PROPN
admet-2088	1026	23	crespo	crespo	PROPN
admet-2088	1026	24	-	-	PUNCT
admet-2088	1026	25	barreda	barreda	NOUN
admet-2088	1026	26	,	,	PUNCT
admet-2088	1026	27	m.	m.	NOUN
admet-2088	1026	28	lecea	lecea	PROPN
admet-2088	1026	29	,	,	PUNCT
admet-2088	1026	30	m.	m.	NOUN
admet-2088	1026	31	cordani	cordani	PROPN
admet-2088	1026	32	,	,	PUNCT
admet-2088	1026	33	p.	p.	PROPN
admet-2088	1026	34	martín	martín	NOUN
admet-2088	1026	35	-	-	PUNCT
admet-2088	1026	36	duque	duque	PROPN
admet-2088	1026	37	,	,	PUNCT
admet-2088	1026	38	á	á	PROPN
admet-2088	1026	39	.	.	PUNCT
admet-2088	1027	1	somoza	somoza	PROPN
admet-2088	1027	2	.	.	PUNCT
admet-2088	1028	1	albumin	albumin	NOUN
admet-2088	1028	2	-	-	PUNCT
admet-2088	1028	3	based	base	VERB
admet-2088	1028	4	nanostructures	nanostructure	NOUN
admet-2088	1028	5	for	for	ADP
admet-2088	1028	6	uveal	uveal	ADJ
admet-2088	1028	7	melanoma	melanoma	NOUN
admet-2088	1028	8	https://doi.org/10.1016/j.jconrel.2022.06.021	https://doi.org/10.1016/j.jconrel.2022.06.021	PROPN
admet-2088	1028	9	https://doi.org/10.1016/j.det.2019.05.001	https://doi.org/10.1016/j.det.2019.05.001	ADJ
admet-2088	1028	10	https://doi.org/10.1038/nrc2966	https://doi.org/10.1038/nrc2966	PRON
admet-2088	1028	11	https://doi.org/10.1016/j.jddst.2021.102847	https://doi.org/10.1016/j.jddst.2021.102847	PROPN
admet-2088	1028	12	https://doi.org/10.1016/j.mtbio.2022.100524	https://doi.org/10.1016/j.mtbio.2022.100524	PROPN
admet-2088	1028	13	https://doi.org/10.1016/j.molliq.2022.121046	https://doi.org/10.1016/j.molliq.2022.121046	PROPN
admet-2088	1028	14	https://doi.org/10.1016/j.mattod.2022.11.007	https://doi.org/10.1016/j.mattod.2022.11.007	PROPN
admet-2088	1028	15	https://doi.org/10.1021/nn800072	https://doi.org/10.1021/nn800072	PROPN
admet-2088	1028	16	t	t	PROPN
admet-2088	1028	17	https://doi.org/10.1016/j.nantod.2017.06.008	https://doi.org/10.1016/j.nantod.2017.06.008	PROPN
admet-2088	1028	18	https://doi.org/10.1098/rstl.1857.0011	https://doi.org/10.1098/rstl.1857.0011	PROPN
admet-2088	1028	19	https://doi.org/10.1021/nl202559p	https://doi.org/10.1021/nl202559p	X
admet-2088	1029	1	https://doi.org/10.1007/s00449-019-02210-w	https://doi.org/10.1007/s00449-019-02210-w	PROPN
admet-2088	1029	2	https://doi.org/10.4155/tde.12.21	https://doi.org/10.4155/tde.12.21	PROPN
admet-2088	1029	3	https://doi.org/10.1021/acs.biomac.8b01690	https://doi.org/10.1021/acs.biomac.8b01690	PROPN
admet-2088	1029	4	https://doi.org/10.1016/j.msec.2019.01.123	https://doi.org/10.1016/j.msec.2019.01.123	PROPN
admet-2088	1029	5	https://doi.org/10.1016/j.nano.2023.102662	https://doi.org/10.1016/j.nano.2023.102662	PROPN
admet-2088	1029	6	admet	admet	PROPN
admet-2088	1029	7	&	&	CCONJ
admet-2088	1029	8	dmpk	dmpk	PROPN
admet-2088	1029	9	12(1	12(1	PROPN
admet-2088	1029	10	)	)	PUNCT
admet-2088	1029	11	(	(	PUNCT
admet-2088	1029	12	2024	2024	NUM
admet-2088	1029	13	)	)	PUNCT
admet-2088	1029	14	107	107	NUM
admet-2088	1029	15	-	-	SYM
admet-2088	1029	16	150	150	NUM
admet-2088	1029	17	nanomaterial	nanomaterial	NOUN
admet-2088	1029	18	-	-	PUNCT
admet-2088	1029	19	based	base	VERB
admet-2088	1029	20	drug	drug	NOUN
admet-2088	1029	21	delivery	delivery	NOUN
admet-2088	1029	22	systems	system	NOUN
admet-2088	1029	23	for	for	ADP
admet-2088	1029	24	melanoma	melanoma	NOUN
admet-2088	1029	25	therapy	therapy	NOUN
admet-2088	1029	26	doi	doi	NOUN
admet-2088	1029	27	:	:	PUNCT
admet-2088	1029	28	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	1029	29	141	141	NUM
admet-2088	1029	30	treatment	treatment	NOUN
admet-2088	1029	31	.	.	PUNCT
admet-2088	1030	1	nanomedicine	nanomedicine	NOUN
admet-2088	1030	2	:	:	PUNCT
admet-2088	1030	3	nanotechnology	nanotechnology	NOUN
admet-2088	1030	4	,	,	PUNCT
admet-2088	1030	5	biology	biology	NOUN
admet-2088	1030	6	,	,	PUNCT
admet-2088	1030	7	and	and	CCONJ
admet-2088	1030	8	medicine	medicine	NOUN
admet-2088	1030	9	35	35	NUM
admet-2088	1030	10	(	(	PUNCT
admet-2088	1030	11	2021	2021	NUM
admet-2088	1030	12	)	)	PUNCT
admet-2088	1030	13	102391	102391	NUM
admet-2088	1030	14	.	.	PUNCT
admet-2088	1031	1	https://doi.org/10.1016/j.nano.2021.102391	https://doi.org/10.1016/j.nano.2021.102391	PROPN
admet-2088	1031	2	.	.	PUNCT
admet-2088	1032	1	[	[	X
admet-2088	1032	2	81	81	NUM
admet-2088	1032	3	]	]	X
admet-2088	1032	4	l.k	l.k	PROPN
admet-2088	1032	5	.	.	PROPN
admet-2088	1032	6	caesar	caesar	PROPN
admet-2088	1032	7	,	,	PUNCT
admet-2088	1032	8	n.b	n.b	PROPN
admet-2088	1032	9	.	.	PROPN
admet-2088	1032	10	cech	cech	PROPN
admet-2088	1032	11	.	.	PUNCT
admet-2088	1033	1	a	a	DET
admet-2088	1033	2	review	review	NOUN
admet-2088	1033	3	of	of	ADP
admet-2088	1033	4	the	the	DET
admet-2088	1033	5	medicinal	medicinal	ADJ
admet-2088	1033	6	uses	use	NOUN
admet-2088	1033	7	and	and	CCONJ
admet-2088	1033	8	pharmacology	pharmacology	NOUN
admet-2088	1033	9	of	of	ADP
admet-2088	1033	10	ashitaba	ashitaba	PROPN
admet-2088	1033	11	.	.	PUNCT
admet-2088	1034	1	planta	planta	PROPN
admet-2088	1034	2	medica	medica	PROPN
admet-2088	1034	3	82	82	NUM
admet-2088	1034	4	(	(	PUNCT
admet-2088	1034	5	2016	2016	NUM
admet-2088	1034	6	)	)	PUNCT
admet-2088	1034	7	1236	1236	NUM
admet-2088	1034	8	-	-	SYM
admet-2088	1034	9	1245	1245	NUM
admet-2088	1034	10	.	.	PUNCT
admet-2088	1035	1	https://doi.org/10.1055/s-0042-110496	https://doi.org/10.1055/s-0042-110496	NOUN
admet-2088	1035	2	.	.	PUNCT
admet-2088	1036	1	[	[	X
admet-2088	1036	2	82	82	NUM
admet-2088	1036	3	]	]	X
admet-2088	1036	4	f.	f.	PROPN
admet-2088	1036	5	wu	wu	PROPN
admet-2088	1036	6	,	,	PUNCT
admet-2088	1036	7	j.	j.	PROPN
admet-2088	1036	8	zhu	zhu	PROPN
admet-2088	1036	9	,	,	PUNCT
admet-2088	1036	10	g.	g.	PROPN
admet-2088	1036	11	li	li	PROPN
admet-2088	1036	12	,	,	PUNCT
admet-2088	1036	13	j.	j.	PROPN
admet-2088	1036	14	wang	wang	PROPN
admet-2088	1036	15	,	,	PUNCT
admet-2088	1036	16	v.p	v.p	PROPN
admet-2088	1036	17	.	.	PROPN
admet-2088	1036	18	veeraraghavan	veeraraghavan	PROPN
admet-2088	1036	19	,	,	PUNCT
admet-2088	1036	20	s.k	s.k	PROPN
admet-2088	1036	21	.	.	PROPN
admet-2088	1036	22	mohan	mohan	PROPN
admet-2088	1036	23	,	,	PUNCT
admet-2088	1036	24	q.	q.	PROPN
admet-2088	1036	25	zhan	zhan	PROPN
admet-2088	1036	26	.	.	PUNCT
admet-2088	1037	1	biologically	biologically	ADV
admet-2088	1037	2	synthesized	synthesize	VERB
admet-2088	1037	3	green	green	ADJ
admet-2088	1037	4	gold	gold	NOUN
admet-2088	1037	5	nanoparticles	nanoparticle	NOUN
admet-2088	1037	6	from	from	ADP
admet-2088	1037	7	siberian	siberian	ADJ
admet-2088	1037	8	ginseng	ginseng	NOUN
admet-2088	1037	9	induce	induce	VERB
admet-2088	1037	10	growth	growth	NOUN
admet-2088	1037	11	-	-	PUNCT
admet-2088	1037	12	inhibitory	inhibitory	ADJ
admet-2088	1037	13	effect	effect	NOUN
admet-2088	1037	14	on	on	ADP
admet-2088	1037	15	melanoma	melanoma	NOUN
admet-2088	1037	16	cells	cell	NOUN
admet-2088	1037	17	(	(	PUNCT
admet-2088	1037	18	b16	b16	PROPN
admet-2088	1037	19	)	)	PUNCT
admet-2088	1037	20	.	.	PUNCT
admet-2088	1038	1	artificial	artificial	ADJ
admet-2088	1038	2	cells	cell	NOUN
admet-2088	1038	3	,	,	PUNCT
admet-2088	1038	4	nanomedicine	nanomedicine	NOUN
admet-2088	1038	5	,	,	PUNCT
admet-2088	1038	6	and	and	CCONJ
admet-2088	1038	7	biotechnology	biotechnology	NOUN
admet-2088	1038	8	47	47	NUM
admet-2088	1038	9	(	(	PUNCT
admet-2088	1038	10	2019	2019	NUM
admet-2088	1038	11	)	)	PUNCT
admet-2088	1038	12	3297	3297	NUM
admet-2088	1038	13	-	-	SYM
admet-2088	1038	14	3305	3305	NUM
admet-2088	1038	15	.	.	PUNCT
admet-2088	1039	1	https://doi.org/10.1080/21691401.2019.1647224	https://doi.org/10.1080/21691401.2019.1647224	PROPN
admet-2088	1039	2	.	.	PUNCT
admet-2088	1040	1	[	[	X
admet-2088	1040	2	83	83	NUM
admet-2088	1040	3	]	]	X
admet-2088	1040	4	n.	n.	NOUN
admet-2088	1040	5	zahraie	zahraie	PROPN
admet-2088	1040	6	,	,	PUNCT
admet-2088	1040	7	g.	g.	PROPN
admet-2088	1040	8	perota	perota	PROPN
admet-2088	1040	9	,	,	PUNCT
admet-2088	1040	10	r.	r.	PROPN
admet-2088	1040	11	dehdari	dehdari	PROPN
admet-2088	1040	12	vais	vais	PROPN
admet-2088	1040	13	,	,	PUNCT
admet-2088	1040	14	n.	n.	PROPN
admet-2088	1040	15	sattarahmady	sattarahmady	PROPN
admet-2088	1040	16	.	.	PUNCT
admet-2088	1041	1	simultaneous	simultaneous	ADJ
admet-2088	1041	2	chemotherapy	chemotherapy	NOUN
admet-2088	1041	3	/	/	SYM
admet-2088	1041	4	sonodynamic	sonodynamic	ADJ
admet-2088	1041	5	therapy	therapy	NOUN
admet-2088	1041	6	of	of	ADP
admet-2088	1041	7	the	the	DET
admet-2088	1041	8	melanoma	melanoma	NOUN
admet-2088	1041	9	cancer	cancer	NOUN
admet-2088	1041	10	cells	cell	NOUN
admet-2088	1041	11	using	use	VERB
admet-2088	1041	12	a	a	DET
admet-2088	1041	13	gold	gold	NOUN
admet-2088	1041	14	-	-	PUNCT
admet-2088	1041	15	paclitaxel	paclitaxel	NOUN
admet-2088	1041	16	nanostructure	nanostructure	NOUN
admet-2088	1041	17	.	.	PUNCT
admet-2088	1042	1	photodiagnosis	photodiagnosis	NOUN
admet-2088	1042	2	and	and	CCONJ
admet-2088	1042	3	photodynamic	photodynamic	ADJ
admet-2088	1042	4	therapy	therapy	NOUN
admet-2088	1042	5	39	39	NUM
admet-2088	1042	6	(	(	PUNCT
admet-2088	1042	7	2022	2022	NUM
admet-2088	1042	8	)	)	PUNCT
admet-2088	1042	9	102991	102991	NUM
admet-2088	1042	10	.	.	PUNCT
admet-2088	1043	1	https://doi.org/10.1016/j.pdpdt.2022.102991	https://doi.org/10.1016/j.pdpdt.2022.102991	NOUN
admet-2088	1043	2	.	.	PUNCT
admet-2088	1044	1	[	[	X
admet-2088	1044	2	84	84	NUM
admet-2088	1044	3	]	]	X
admet-2088	1044	4	l.	l.	PROPN
admet-2088	1044	5	brochez	brochez	PROPN
admet-2088	1044	6	,	,	PUNCT
admet-2088	1044	7	a.	a.	NOUN
admet-2088	1044	8	meireson	meireson	NOUN
admet-2088	1044	9	,	,	PUNCT
admet-2088	1044	10	i.	i.	NOUN
admet-2088	1044	11	chevolet	chevolet	PROPN
admet-2088	1044	12	,	,	PUNCT
admet-2088	1044	13	n.	n.	PROPN
admet-2088	1044	14	sundahl	sundahl	PROPN
admet-2088	1044	15	,	,	PUNCT
admet-2088	1044	16	p.	p.	NOUN
admet-2088	1044	17	ost	ost	PROPN
admet-2088	1044	18	,	,	PUNCT
admet-2088	1044	19	v.	v.	PROPN
admet-2088	1044	20	kruse	kruse	PROPN
admet-2088	1044	21	.	.	PUNCT
admet-2088	1045	1	challenging	challenge	VERB
admet-2088	1045	2	pd	pd	PROPN
admet-2088	1045	3	-	-	PROPN
admet-2088	1045	4	l1	l1	PROPN
admet-2088	1045	5	expressing	express	VERB
admet-2088	1045	6	cytotoxic	cytotoxic	ADJ
admet-2088	1045	7	t	t	NOUN
admet-2088	1045	8	cells	cell	NOUN
admet-2088	1045	9	as	as	ADP
admet-2088	1045	10	a	a	DET
admet-2088	1045	11	predictor	predictor	NOUN
admet-2088	1045	12	for	for	ADP
admet-2088	1045	13	response	response	NOUN
admet-2088	1045	14	to	to	ADP
admet-2088	1045	15	immunotherapy	immunotherapy	NOUN
admet-2088	1045	16	in	in	ADP
admet-2088	1045	17	melanoma	melanoma	NOUN
admet-2088	1045	18	.	.	PUNCT
admet-2088	1046	1	nature	nature	NOUN
admet-2088	1046	2	communications	communication	NOUN
admet-2088	1046	3	9	9	NUM
admet-2088	1046	4	(	(	PUNCT
admet-2088	1046	5	2018	2018	NUM
admet-2088	1046	6	)	)	PUNCT
admet-2088	1046	7	2921	2921	NUM
admet-2088	1046	8	.	.	PUNCT
admet-2088	1047	1	https://doi.org/10.1038/s41467-018-05047-1	https://doi.org/10.1038/s41467-018-05047-1	NOUN
admet-2088	1047	2	.	.	PUNCT
admet-2088	1048	1	[	[	X
admet-2088	1048	2	85	85	NUM
admet-2088	1048	3	]	]	PUNCT
admet-2088	1048	4	a.	a.	NOUN
admet-2088	1048	5	banstola	banstola	PROPN
admet-2088	1048	6	,	,	PUNCT
admet-2088	1048	7	k.	k.	PROPN
admet-2088	1048	8	poudel	poudel	PROPN
admet-2088	1048	9	,	,	PUNCT
admet-2088	1048	10	f.	f.	PROPN
admet-2088	1048	11	emami	emami	PROPN
admet-2088	1048	12	,	,	PUNCT
admet-2088	1048	13	s.k	s.k	PROPN
admet-2088	1048	14	.	.	PROPN
admet-2088	1048	15	ku	ku	PROPN
admet-2088	1048	16	,	,	PUNCT
admet-2088	1048	17	j.-h	j.-h	PROPN
admet-2088	1048	18	.	.	PUNCT
admet-2088	1049	1	jeong	jeong	PROPN
admet-2088	1049	2	,	,	PUNCT
admet-2088	1049	3	j.o	j.o	PROPN
admet-2088	1049	4	.	.	PROPN
admet-2088	1049	5	kim	kim	PROPN
admet-2088	1049	6	,	,	PUNCT
admet-2088	1049	7	s.	s.	PROPN
admet-2088	1049	8	yook	yook	PROPN
admet-2088	1049	9	.	.	PUNCT
admet-2088	1050	1	localized	localize	VERB
admet-2088	1050	2	therapy	therapy	NOUN
admet-2088	1050	3	using	use	VERB
admet-2088	1050	4	antipd	antipd	NOUN
admet-2088	1050	5	-	-	PUNCT
admet-2088	1050	6	l1	l1	PROPN
admet-2088	1050	7	anchored	anchor	VERB
admet-2088	1050	8	and	and	CCONJ
admet-2088	1050	9	nir	nir	ADJ
admet-2088	1050	10	-	-	PUNCT
admet-2088	1050	11	responsive	responsive	ADJ
admet-2088	1050	12	hollow	hollow	ADJ
admet-2088	1050	13	gold	gold	NOUN
admet-2088	1050	14	nanoshell	nanoshell	NOUN
admet-2088	1050	15	(	(	PUNCT
admet-2088	1050	16	hgns	hgns	PROPN
admet-2088	1050	17	)	)	PUNCT
admet-2088	1050	18	loaded	load	VERB
admet-2088	1050	19	with	with	ADP
admet-2088	1050	20	doxorubicin	doxorubicin	PROPN
admet-2088	1050	21	(	(	PUNCT
admet-2088	1050	22	dox	dox	NOUN
admet-2088	1050	23	)	)	PUNCT
admet-2088	1050	24	for	for	ADP
admet-2088	1050	25	the	the	DET
admet-2088	1050	26	treatment	treatment	NOUN
admet-2088	1050	27	of	of	ADP
admet-2088	1050	28	locally	locally	ADV
admet-2088	1050	29	advanced	advanced	ADJ
admet-2088	1050	30	melanoma	melanoma	NOUN
admet-2088	1050	31	.	.	PUNCT
admet-2088	1051	1	nanomedicine	nanomedicine	NOUN
admet-2088	1051	2	:	:	PUNCT
admet-2088	1051	3	nanotechnology	nanotechnology	NOUN
admet-2088	1051	4	,	,	PUNCT
admet-2088	1051	5	biology	biology	NOUN
admet-2088	1051	6	,	,	PUNCT
admet-2088	1051	7	and	and	CCONJ
admet-2088	1051	8	medicine	medicine	NOUN
admet-2088	1051	9	33	33	NUM
admet-2088	1051	10	(	(	PUNCT
admet-2088	1051	11	2021	2021	NUM
admet-2088	1051	12	)	)	PUNCT
admet-2088	1051	13	102349	102349	NUM
admet-2088	1051	14	.	.	PUNCT
admet-2088	1052	1	https://doi.org/10.1016/j.nano.2020.102349	https://doi.org/10.1016/j.nano.2020.102349	NOUN
admet-2088	1052	2	.	.	PUNCT
admet-2088	1053	1	[	[	X
admet-2088	1053	2	86	86	NUM
admet-2088	1053	3	]	]	X
admet-2088	1053	4	g.	g.	PROPN
admet-2088	1053	5	farahavar	farahavar	PROPN
admet-2088	1053	6	,	,	PUNCT
admet-2088	1053	7	s.s	s.s	PROPN
admet-2088	1053	8	.	.	PROPN
admet-2088	1053	9	abolmaali	abolmaali	PROPN
admet-2088	1053	10	,	,	PUNCT
admet-2088	1053	11	f.	f.	PROPN
admet-2088	1053	12	nejatollahi	nejatollahi	PROPN
admet-2088	1053	13	,	,	PUNCT
admet-2088	1053	14	a.	a.	NOUN
admet-2088	1053	15	safaie	safaie	PROPN
admet-2088	1053	16	,	,	PUNCT
admet-2088	1053	17	s.	s.	PROPN
admet-2088	1053	18	javanmardi	javanmardi	PROPN
admet-2088	1053	19	,	,	PUNCT
admet-2088	1053	20	h.k	h.k	PROPN
admet-2088	1053	21	.	.	PROPN
admet-2088	1053	22	zadeh	zadeh	PROPN
admet-2088	1053	23	,	,	PUNCT
admet-2088	1053	24	r.	r.	PROPN
admet-2088	1053	25	yousefi	yousefi	PROPN
admet-2088	1053	26	,	,	PUNCT
admet-2088	1053	27	h.	h.	PROPN
admet-2088	1053	28	nadgaran	nadgaran	PROPN
admet-2088	1053	29	,	,	PUNCT
admet-2088	1053	30	s.	s.	PROPN
admet-2088	1053	31	mohammadi	mohammadi	PROPN
admet-2088	1053	32	-	-	PUNCT
admet-2088	1053	33	samani	samani	ADJ
admet-2088	1053	34	,	,	PUNCT
admet-2088	1053	35	a.md	a.md	PROPN
admet-2088	1053	36	.	.	PUNCT
admet-2088	1053	37	tamaddon	tamaddon	PROPN
admet-2088	1053	38	,	,	PUNCT
admet-2088	1053	39	s.	s.	PROPN
admet-2088	1053	40	ahadian	ahadian	PROPN
admet-2088	1053	41	.	.	PUNCT
admet-2088	1054	1	single	single	ADJ
admet-2088	1054	2	-	-	PUNCT
admet-2088	1054	3	chain	chain	NOUN
admet-2088	1054	4	antibody	antibody	NOUN
admet-2088	1054	5	-	-	PUNCT
admet-2088	1054	6	decorated	decorate	VERB
admet-2088	1054	7	au	au	ADJ
admet-2088	1054	8	nanocages@liposomal	nanocages@liposomal	ADJ
admet-2088	1054	9	layer	layer	NOUN
admet-2088	1054	10	nanoprobes	nanoprobe	NOUN
admet-2088	1054	11	for	for	ADP
admet-2088	1054	12	targeted	target	VERB
admet-2088	1054	13	sers	ser	NOUN
admet-2088	1054	14	imaging	imaging	NOUN
admet-2088	1054	15	and	and	CCONJ
admet-2088	1054	16	remote	remote	ADV
admet-2088	1054	17	-	-	PUNCT
admet-2088	1054	18	controlled	control	VERB
admet-2088	1054	19	photothermal	photothermal	ADJ
admet-2088	1054	20	therapy	therapy	NOUN
admet-2088	1054	21	of	of	ADP
admet-2088	1054	22	melanoma	melanoma	NOUN
admet-2088	1054	23	cancer	cancer	NOUN
admet-2088	1054	24	cells	cell	NOUN
admet-2088	1054	25	.	.	PUNCT
admet-2088	1055	1	materials	material	NOUN
admet-2088	1055	2	science	science	PROPN
admet-2088	1055	3	&	&	CCONJ
admet-2088	1055	4	engineering	engineering	PROPN
admet-2088	1055	5	c	c	PROPN
admet-2088	1055	6	124	124	NUM
admet-2088	1055	7	(	(	PUNCT
admet-2088	1055	8	2021	2021	NUM
admet-2088	1055	9	)	)	PUNCT
admet-2088	1055	10	112086	112086	NUM
admet-2088	1055	11	.	.	PUNCT
admet-2088	1056	1	https://doi.org/10.1016/j.msec.2021.112086	https://doi.org/10.1016/j.msec.2021.112086	ADJ
admet-2088	1056	2	.	.	PUNCT
admet-2088	1057	1	[	[	X
admet-2088	1057	2	87	87	NUM
admet-2088	1057	3	]	]	PUNCT
admet-2088	1057	4	j.	j.	PROPN
admet-2088	1057	5	lopes	lopes	PROPN
admet-2088	1057	6	,	,	PUNCT
admet-2088	1057	7	j.m.p	j.m.p	PROPN
admet-2088	1057	8	.	.	PUNCT
admet-2088	1057	9	coelho	coelho	PROPN
admet-2088	1057	10	,	,	PUNCT
admet-2088	1057	11	p.m.c	p.m.c	PROPN
admet-2088	1057	12	.	.	PROPN
admet-2088	1057	13	vieira	vieira	PROPN
admet-2088	1057	14	,	,	PUNCT
admet-2088	1057	15	a.s	a.s	PROPN
admet-2088	1057	16	.	.	PROPN
admet-2088	1057	17	viana	viana	PROPN
admet-2088	1057	18	,	,	PUNCT
admet-2088	1057	19	m.m	m.m	PROPN
admet-2088	1057	20	.	.	PROPN
admet-2088	1057	21	gaspar	gaspar	PROPN
admet-2088	1057	22	,	,	PUNCT
admet-2088	1057	23	c.	c.	PROPN
admet-2088	1057	24	reis	reis	NOUN
admet-2088	1057	25	.	.	PUNCT
admet-2088	1058	1	preliminary	preliminary	ADJ
admet-2088	1058	2	assays	assay	NOUN
admet-2088	1058	3	towards	towards	ADP
admet-2088	1058	4	melanoma	melanoma	NOUN
admet-2088	1058	5	cells	cell	NOUN
admet-2088	1058	6	using	use	VERB
admet-2088	1058	7	phototherapy	phototherapy	NOUN
admet-2088	1058	8	with	with	ADP
admet-2088	1058	9	gold	gold	NOUN
admet-2088	1058	10	-	-	PUNCT
admet-2088	1058	11	based	base	VERB
admet-2088	1058	12	nanomaterials	nanomaterial	NOUN
admet-2088	1058	13	.	.	PUNCT
admet-2088	1059	1	nanomaterial	nanomaterial	ADJ
admet-2088	1059	2	10	10	NUM
admet-2088	1059	3	(	(	PUNCT
admet-2088	1059	4	2020	2020	NUM
admet-2088	1059	5	)	)	PUNCT
admet-2088	1059	6	1536	1536	NUM
admet-2088	1059	7	.	.	PUNCT
admet-2088	1060	1	https://doi.org/10.3390/nano10081536	https://doi.org/10.3390/nano10081536	NOUN
admet-2088	1060	2	.	.	PUNCT
admet-2088	1061	1	[	[	X
admet-2088	1061	2	88	88	NUM
admet-2088	1061	3	]	]	PUNCT
admet-2088	1061	4	a.	a.	NOUN
admet-2088	1061	5	shanei	shanei	PROPN
admet-2088	1061	6	,	,	PUNCT
admet-2088	1061	7	h.	h.	PROPN
admet-2088	1061	8	akbari	akbari	PROPN
admet-2088	1061	9	-	-	PUNCT
admet-2088	1061	10	zadeh	zadeh	PROPN
admet-2088	1061	11	,	,	PUNCT
admet-2088	1061	12	n.	n.	PROPN
admet-2088	1061	13	attaran	attaran	PROPN
admet-2088	1061	14	,	,	PUNCT
admet-2088	1061	15	m.r	m.r	PROPN
admet-2088	1061	16	.	.	PROPN
admet-2088	1061	17	salamat	salamat	PROPN
admet-2088	1061	18	,	,	PUNCT
admet-2088	1061	19	m.	m.	NOUN
admet-2088	1061	20	baradaran	baradaran	PROPN
admet-2088	1061	21	-	-	PUNCT
admet-2088	1061	22	ghahfarokhi	ghahfarokhi	PROPN
admet-2088	1061	23	.	.	PUNCT
admet-2088	1062	1	effect	effect	NOUN
admet-2088	1062	2	of	of	ADP
admet-2088	1062	3	targeted	target	VERB
admet-2088	1062	4	gold	gold	ADJ
admet-2088	1062	5	nanoparticles	nanoparticle	NOUN
admet-2088	1062	6	size	size	NOUN
admet-2088	1062	7	on	on	ADP
admet-2088	1062	8	acoustic	acoustic	ADJ
admet-2088	1062	9	cavitation	cavitation	NOUN
admet-2088	1062	10	:	:	PUNCT
admet-2088	1062	11	an	an	DET
admet-2088	1062	12	in	in	ADP
admet-2088	1062	13	vitro	vitro	X
admet-2088	1062	14	study	study	NOUN
admet-2088	1062	15	on	on	ADP
admet-2088	1062	16	melanoma	melanoma	NOUN
admet-2088	1062	17	cells	cell	NOUN
admet-2088	1062	18	.	.	PUNCT
admet-2088	1063	1	ultrasonics	ultrasonic	NOUN
admet-2088	1063	2	102	102	NUM
admet-2088	1063	3	(	(	PUNCT
admet-2088	1063	4	2020	2020	NUM
admet-2088	1063	5	)	)	PUNCT
admet-2088	1063	6	106061	106061	NUM
admet-2088	1063	7	-	-	SYM
admet-2088	1063	8	106071	106071	NUM
admet-2088	1063	9	.	.	PUNCT
admet-2088	1064	1	https://doi.org/10.1016/j.ultras.2019.106061	https://doi.org/10.1016/j.ultras.2019.106061	PROPN
admet-2088	1064	2	.	.	PUNCT
admet-2088	1065	1	[	[	X
admet-2088	1065	2	89	89	NUM
admet-2088	1065	3	]	]	X
admet-2088	1065	4	g.	g.	PROPN
admet-2088	1065	5	perota	perota	PROPN
admet-2088	1065	6	,	,	PUNCT
admet-2088	1065	7	n.	n.	PROPN
admet-2088	1065	8	zahraie	zahraie	PROPN
admet-2088	1065	9	,	,	PUNCT
admet-2088	1065	10	r.	r.	PROPN
admet-2088	1065	11	dehdari	dehdari	PROPN
admet-2088	1065	12	vais	vais	PROPN
admet-2088	1065	13	,	,	PUNCT
admet-2088	1065	14	m.h	m.h	PROPN
admet-2088	1065	15	.	.	PROPN
admet-2088	1065	16	zare	zare	PROPN
admet-2088	1065	17	,	,	PUNCT
admet-2088	1065	18	n.	n.	PROPN
admet-2088	1065	19	sattarahmady	sattarahmady	PROPN
admet-2088	1065	20	.	.	PUNCT
admet-2088	1065	21	au	au	PROPN
admet-2088	1065	22	/	/	SYM
admet-2088	1065	23	tio2	tio2	NOUN
admet-2088	1065	24	nanocomposite	nanocomposite	NOUN
admet-2088	1065	25	as	as	ADP
admet-2088	1065	26	a	a	DET
admet-2088	1065	27	triple	triple	ADJ
admet-2088	1065	28	-	-	PUNCT
admet-2088	1065	29	sensitizer	sensitizer	NOUN
admet-2088	1065	30	for	for	ADP
admet-2088	1065	31	808	808	NUM
admet-2088	1065	32	and	and	CCONJ
admet-2088	1065	33	650	650	NUM
admet-2088	1065	34	nm	nm	ADJ
admet-2088	1065	35	phototherapy	phototherapy	NOUN
admet-2088	1065	36	and	and	CCONJ
admet-2088	1065	37	sonotherapy	sonotherapy	NOUN
admet-2088	1065	38	:	:	PUNCT
admet-2088	1065	39	synergistic	synergistic	ADJ
admet-2088	1065	40	therapy	therapy	NOUN
admet-2088	1065	41	of	of	ADP
admet-2088	1065	42	melanoma	melanoma	NOUN
admet-2088	1065	43	cancer	cancer	NOUN
admet-2088	1065	44	in	in	ADP
admet-2088	1065	45	vitro	vitro	X
admet-2088	1065	46	.	.	PUNCT
admet-2088	1066	1	journal	journal	PROPN
admet-2088	1066	2	of	of	ADP
admet-2088	1066	3	drug	drug	NOUN
admet-2088	1066	4	delivery	delivery	NOUN
admet-2088	1066	5	science	science	NOUN
admet-2088	1066	6	and	and	CCONJ
admet-2088	1066	7	technology	technology	NOUN
admet-2088	1066	8	76	76	NUM
admet-2088	1066	9	(	(	PUNCT
admet-2088	1066	10	2022	2022	NUM
admet-2088	1066	11	)	)	PUNCT
admet-2088	1066	12	103787	103787	NUM
admet-2088	1066	13	.	.	PUNCT
admet-2088	1067	1	https://doi.org/10.1016/j.jddst.2022.103787	https://doi.org/10.1016/j.jddst.2022.103787	NOUN
admet-2088	1067	2	.	.	PUNCT
admet-2088	1068	1	[	[	X
admet-2088	1068	2	90	90	NUM
admet-2088	1068	3	]	]	PUNCT
admet-2088	1068	4	e.	e.	PROPN
admet-2088	1068	5	soratijahromia	soratijahromia	PROPN
admet-2088	1068	6	,	,	PUNCT
admet-2088	1068	7	s.	s.	PROPN
admet-2088	1068	8	mohammadia	mohammadia	PROPN
admet-2088	1068	9	,	,	PUNCT
admet-2088	1068	10	r.	r.	PROPN
admet-2088	1068	11	dehdari	dehdari	PROPN
admet-2088	1068	12	vais	vais	PROPN
admet-2088	1068	13	,	,	PUNCT
admet-2088	1068	14	n.	n.	PROPN
admet-2088	1068	15	azarpira	azarpira	PROPN
admet-2088	1068	16	,	,	PUNCT
admet-2088	1068	17	n.	n.	PROPN
admet-2088	1068	18	sattarahmady	sattarahmady	PROPN
admet-2088	1068	19	.	.	PUNCT
admet-2088	1069	1	photothermal	photothermal	ADJ
admet-2088	1069	2	/	/	SYM
admet-2088	1069	3	sonodynamic	sonodynamic	ADJ
admet-2088	1069	4	therapy	therapy	NOUN
admet-2088	1069	5	of	of	ADP
admet-2088	1069	6	melanoma	melanoma	NOUN
admet-2088	1069	7	tumor	tumor	NOUN
admet-2088	1069	8	by	by	ADP
admet-2088	1069	9	a	a	DET
admet-2088	1069	10	gold	gold	NOUN
admet-2088	1069	11	/	/	SYM
admet-2088	1069	12	manganese	manganese	NOUN
admet-2088	1069	13	dioxide	dioxide	NOUN
admet-2088	1069	14	nanocomposite	nanocomposite	NOUN
admet-2088	1069	15	:	:	PUNCT
admet-2088	1069	16	in	in	ADP
admet-2088	1069	17	vitro	vitro	X
admet-2088	1069	18	and	and	CCONJ
admet-2088	1069	19	in	in	ADP
admet-2088	1069	20	vivo	vivo	ADJ
admet-2088	1069	21	studies	study	NOUN
admet-2088	1069	22	.	.	PUNCT
admet-2088	1070	1	photodiagnosis	photodiagnosis	NOUN
admet-2088	1070	2	and	and	CCONJ
admet-2088	1070	3	photodynamic	photodynamic	ADJ
admet-2088	1070	4	therapy	therapy	NOUN
admet-2088	1070	5	31	31	NUM
admet-2088	1070	6	(	(	PUNCT
admet-2088	1070	7	2020	2020	NUM
admet-2088	1070	8	)	)	PUNCT
admet-2088	1070	9	101846	101846	NUM
admet-2088	1070	10	.	.	PUNCT
admet-2088	1071	1	https://doi.org/10.1016/j.pdpdt.2020.101846	https://doi.org/10.1016/j.pdpdt.2020.101846	NOUN
admet-2088	1071	2	.	.	PUNCT
admet-2088	1072	1	[	[	X
admet-2088	1072	2	91	91	NUM
admet-2088	1072	3	]	]	X
admet-2088	1072	4	r.p	r.p	PROPN
admet-2088	1072	5	.	.	PROPN
admet-2088	1072	6	singh	singh	PROPN
admet-2088	1072	7	,	,	PUNCT
admet-2088	1072	8	c.r.k	c.r.k	PROPN
admet-2088	1072	9	.	.	PUNCT
admet-2088	1072	10	reddy	reddy	PROPN
admet-2088	1072	11	.	.	PUNCT
admet-2088	1073	1	seaweed	seaweed	NOUN
admet-2088	1073	2	-	-	PUNCT
admet-2088	1073	3	microbial	microbial	ADJ
admet-2088	1073	4	interactions	interaction	NOUN
admet-2088	1073	5	:	:	PUNCT
admet-2088	1073	6	key	key	ADJ
admet-2088	1073	7	functions	function	NOUN
admet-2088	1073	8	of	of	ADP
admet-2088	1073	9	seaweed	seaweed	NOUN
admet-2088	1073	10	-	-	PUNCT
admet-2088	1073	11	associated	associate	VERB
admet-2088	1073	12	bacteria	bacteria	NOUN
admet-2088	1073	13	.	.	PUNCT
admet-2088	1074	1	fems	fems	PROPN
admet-2088	1074	2	microbiology	microbiology	NOUN
admet-2088	1074	3	ecology	ecology	NOUN
admet-2088	1074	4	88	88	NUM
admet-2088	1074	5	(	(	PUNCT
admet-2088	1074	6	2014	2014	NUM
admet-2088	1074	7	)	)	PUNCT
admet-2088	1074	8	213	213	NUM
admet-2088	1074	9	-	-	SYM
admet-2088	1074	10	230	230	NUM
admet-2088	1074	11	.	.	PUNCT
admet-2088	1075	1	https://doi.org/10.1111/1574-6941.12297	https://doi.org/10.1111/1574-6941.12297	PROPN
admet-2088	1075	2	.	.	PUNCT
admet-2088	1076	1	[	[	X
admet-2088	1076	2	92	92	NUM
admet-2088	1076	3	]	]	X
admet-2088	1076	4	d.	d.	PROPN
admet-2088	1076	5	acharya	acharya	PROPN
admet-2088	1076	6	,	,	PUNCT
admet-2088	1076	7	s.	s.	PROPN
admet-2088	1076	8	satapathy	satapathy	PROPN
admet-2088	1076	9	,	,	PUNCT
admet-2088	1076	10	p.	p.	NOUN
admet-2088	1076	11	somu	somu	NOUN
admet-2088	1076	12	,	,	PUNCT
admet-2088	1076	13	u.k	u.k	PROPN
admet-2088	1076	14	.	.	PROPN
admet-2088	1076	15	parida	parida	PROPN
admet-2088	1076	16	,	,	PUNCT
admet-2088	1077	1	g.	g.	PROPN
admet-2088	1077	2	mishra	mishra	PROPN
admet-2088	1077	3	.	.	PROPN
admet-2088	1078	1	apoptotic	apoptotic	ADJ
admet-2088	1078	2	effect	effect	NOUN
admet-2088	1078	3	and	and	CCONJ
admet-2088	1078	4	anticancer	anticancer	NOUN
admet-2088	1078	5	activity	activity	NOUN
admet-2088	1078	6	of	of	ADP
admet-2088	1078	7	biosynthesized	biosynthesize	VERB
admet-2088	1078	8	silver	silver	ADJ
admet-2088	1078	9	nanoparticles	nanoparticle	NOUN
admet-2088	1078	10	from	from	ADP
admet-2088	1078	11	marine	marine	ADJ
admet-2088	1078	12	algae	algae	NOUN
admet-2088	1078	13	chaetomorpha	chaetomorpha	PROPN
admet-2088	1078	14	linum	linum	PROPN
admet-2088	1078	15	extract	extract	NOUN
admet-2088	1078	16	against	against	ADP
admet-2088	1078	17	human	human	ADJ
admet-2088	1078	18	colon	colon	NOUN
admet-2088	1078	19	cancer	cancer	NOUN
admet-2088	1078	20	cell	cell	NOUN
admet-2088	1078	21	hct-116	hct-116	NOUN
admet-2088	1078	22	.	.	PUNCT
admet-2088	1079	1	biological	biological	ADJ
admet-2088	1079	2	trace	trace	NOUN
admet-2088	1079	3	element	element	NOUN
admet-2088	1079	4	research	research	NOUN
admet-2088	1079	5	199	199	NUM
admet-2088	1079	6	(	(	PUNCT
admet-2088	1079	7	2021	2021	NUM
admet-2088	1079	8	)	)	PUNCT
admet-2088	1079	9	1812	1812	NUM
admet-2088	1079	10	-	-	SYM
admet-2088	1079	11	1822	1822	NUM
admet-2088	1079	12	.	.	PUNCT
admet-2088	1080	1	https://doi.org/10.1007/s12011-020-02304-7	https://doi.org/10.1007/s12011-020-02304-7	X
admet-2088	1080	2	.	.	PUNCT
admet-2088	1081	1	[	[	X
admet-2088	1081	2	93	93	NUM
admet-2088	1081	3	]	]	X
admet-2088	1081	4	w.i	w.i	PROPN
admet-2088	1081	5	.	.	PROPN
admet-2088	1081	6	abdel	abdel	PROPN
admet-2088	1081	7	-	-	PUNCT
admet-2088	1081	8	fattah	fattah	PROPN
admet-2088	1081	9	,	,	PUNCT
admet-2088	1081	10	g.w	g.w	PROPN
admet-2088	1081	11	.	.	PROPN
admet-2088	1081	12	ali	ali	PROPN
admet-2088	1081	13	.	.	PROPN
admet-2088	1082	1	on	on	ADP
admet-2088	1082	2	the	the	DET
admet-2088	1082	3	anti	anti	ADJ
admet-2088	1082	4	-	-	ADJ
admet-2088	1082	5	cancer	cancer	ADJ
admet-2088	1082	6	activities	activity	NOUN
admet-2088	1082	7	of	of	ADP
admet-2088	1082	8	silver	silver	ADJ
admet-2088	1082	9	nanoparticles	nanoparticle	NOUN
admet-2088	1082	10	.	.	PUNCT
admet-2088	1083	1	journal	journal	NOUN
admet-2088	1083	2	of	of	ADP
admet-2088	1083	3	applied	apply	VERB
admet-2088	1083	4	biotechnology	biotechnology	NOUN
admet-2088	1083	5	&	&	CCONJ
admet-2088	1083	6	bioengineering	bioengineere	VERB
admet-2088	1083	7	5	5	NUM
admet-2088	1083	8	(	(	PUNCT
admet-2088	1083	9	2018	2018	NUM
admet-2088	1083	10	)	)	PUNCT
admet-2088	1083	11	3	3	NUM
admet-2088	1083	12	-	-	SYM
admet-2088	1083	13	7	7	NUM
admet-2088	1083	14	.	.	PUNCT
admet-2088	1084	1	https://doi.org/10.15406/jabb.2018.05.00116	https://doi.org/10.15406/jabb.2018.05.00116	PROPN
admet-2088	1084	2	.	.	PUNCT
admet-2088	1085	1	[	[	X
admet-2088	1085	2	94	94	NUM
admet-2088	1085	3	]	]	PUNCT
admet-2088	1085	4	a.	a.	NOUN
admet-2088	1085	5	sharma	sharma	PROPN
admet-2088	1085	6	,	,	PUNCT
admet-2088	1085	7	a.k	a.k	PROPN
admet-2088	1085	8	.	.	PROPN
admet-2088	1085	9	goyal	goyal	PROPN
admet-2088	1085	10	,	,	PUNCT
admet-2088	1085	11	g.	g.	PROPN
admet-2088	1085	12	rath	rath	PROPN
admet-2088	1085	13	.	.	PUNCT
admet-2088	1086	1	recent	recent	ADJ
admet-2088	1086	2	advances	advance	NOUN
admet-2088	1086	3	in	in	ADP
admet-2088	1086	4	metal	metal	NOUN
admet-2088	1086	5	nanoparticles	nanoparticle	NOUN
admet-2088	1086	6	in	in	ADP
admet-2088	1086	7	cancer	cancer	NOUN
admet-2088	1086	8	therapy	therapy	NOUN
admet-2088	1086	9	.	.	PUNCT
admet-2088	1087	1	journal	journal	PROPN
admet-2088	1087	2	of	of	ADP
admet-2088	1087	3	drug	drug	NOUN
admet-2088	1087	4	target	target	NOUN
admet-2088	1087	5	26	26	NUM
admet-2088	1087	6	(	(	PUNCT
admet-2088	1087	7	2018	2018	NUM
admet-2088	1087	8	)	)	PUNCT
admet-2088	1087	9	617	617	NUM
admet-2088	1087	10	-	-	SYM
admet-2088	1087	11	632	632	NUM
admet-2088	1087	12	.	.	PUNCT
admet-2088	1088	1	https://doi.org/10.1080/1061186x.2017.1400553	https://doi.org/10.1080/1061186x.2017.1400553	X
admet-2088	1088	2	.	.	PUNCT
admet-2088	1089	1	[	[	X
admet-2088	1089	2	95	95	NUM
admet-2088	1089	3	]	]	PUNCT
admet-2088	1089	4	m.	m.	NOUN
admet-2088	1089	5	shahriari	shahriari	PROPN
admet-2088	1089	6	,	,	PUNCT
admet-2088	1089	7	m.a	m.a	PROPN
admet-2088	1089	8	.	.	PROPN
admet-2088	1089	9	sedigh	sedigh	PROPN
admet-2088	1089	10	,	,	PUNCT
admet-2088	1089	11	y.	y.	PROPN
admet-2088	1089	12	mahdavian	mahdavian	PROPN
admet-2088	1089	13	,	,	PUNCT
admet-2088	1089	14	s.	s.	PROPN
admet-2088	1089	15	mahdigholizad	mahdigholizad	PROPN
admet-2088	1089	16	,	,	PUNCT
admet-2088	1089	17	m.	m.	NOUN
admet-2088	1089	18	pirhayati	pirhayati	PROPN
admet-2088	1089	19	,	,	PUNCT
admet-2088	1089	20	b.	b.	PROPN
admet-2088	1089	21	karmakar	karmakar	PROPN
admet-2088	1089	22	,	,	PUNCT
admet-2088	1089	23	h.	h.	PROPN
admet-2088	1089	24	veisi	veisi	VERB
admet-2088	1089	25	.	.	PUNCT
admet-2088	1090	1	in	in	ADP
admet-2088	1090	2	situ	situ	PROPN
admet-2088	1090	3	supported	support	VERB
admet-2088	1090	4	pd	pd	PROPN
admet-2088	1090	5	nps	nps	PROPN
admet-2088	1090	6	on	on	ADP
admet-2088	1090	7	biodegradable	biodegradable	ADJ
admet-2088	1090	8	chitosan	chitosan	NOUN
admet-2088	1090	9	/	/	SYM
admet-2088	1090	10	agarose	agarose	NOUN
admet-2088	1090	11	modified	modify	VERB
admet-2088	1090	12	magnetic	magnetic	ADJ
admet-2088	1090	13	nanoparticles	nanoparticle	NOUN
admet-2088	1090	14	as	as	ADP
admet-2088	1090	15	an	an	DET
admet-2088	1090	16	effective	effective	ADJ
admet-2088	1090	17	catalyst	catalyst	NOUN
admet-2088	1090	18	for	for	ADP
admet-2088	1090	19	the	the	DET
admet-2088	1090	20	ultrasound	ultrasound	NOUN
admet-2088	1090	21	assisted	assist	VERB
admet-2088	1090	22	oxidation	oxidation	NOUN
admet-2088	1090	23	of	of	ADP
admet-2088	1090	24	alcohols	alcohol	NOUN
admet-2088	1090	25	and	and	CCONJ
admet-2088	1090	26	activities	activity	NOUN
admet-2088	1090	27	against	against	ADP
admet-2088	1090	28	human	human	ADJ
admet-2088	1090	29	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	PROPN
admet-2088	1090	30	https://doi.org/10.1016/j.nano.2021.102391	https://doi.org/10.1016/j.nano.2021.102391	PROPN
admet-2088	1090	31	https://doi.org/10.1055/s-0042-110496	https://doi.org/10.1055/s-0042-110496	NOUN
admet-2088	1090	32	https://doi.org/10.1080/21691401.2019.1647224	https://doi.org/10.1080/21691401.2019.1647224	PUNCT
admet-2088	1091	1	https://doi.org/10.1016/j.pdpdt.2022.102991	https://doi.org/10.1016/j.pdpdt.2022.102991	ADJ
admet-2088	1091	2	https://doi.org/10.1038/s41467-018-05047-1	https://doi.org/10.1038/s41467-018-05047-1	VERB
admet-2088	1091	3	https://doi.org/10.1016/j.nano.2020.102349	https://doi.org/10.1016/j.nano.2020.102349	PROPN
admet-2088	1091	4	https://doi.org/10.1016/j.msec.2021.112086	https://doi.org/10.1016/j.msec.2021.112086	ADJ
admet-2088	1091	5	https://doi.org/10.3390/nano10081536	https://doi.org/10.3390/nano10081536	NOUN
admet-2088	1091	6	https://doi.org/10.1016/j.ultras.2019.106061	https://doi.org/10.1016/j.ultras.2019.106061	PROPN
admet-2088	1091	7	https://doi.org/10.1016/j.jddst.2022.103787	https://doi.org/10.1016/j.jddst.2022.103787	PROPN
admet-2088	1091	8	https://doi.org/10.1016/j.pdpdt.2020.101846	https://doi.org/10.1016/j.pdpdt.2020.101846	PROPN
admet-2088	1091	9	https://doi.org/10.1111/1574-6941.12297	https://doi.org/10.1111/1574-6941.12297	PROPN
admet-2088	1091	10	https://doi.org/10.1007/s12011-020-02304-7	https://doi.org/10.1007/s12011-020-02304-7	PROPN
admet-2088	1092	1	https://doi.org/10.15406/jabb.2018.05.00116	https://doi.org/10.15406/jabb.2018.05.00116	PROPN
admet-2088	1092	2	https://doi.org/10.1080/1061186x.2017.1400553	https://doi.org/10.1080/1061186x.2017.1400553	PROPN
admet-2088	1092	3	m.	m.	NOUN
admet-2088	1092	4	kulkarni	kulkarni	PROPN
admet-2088	1092	5	et	et	PROPN
admet-2088	1092	6	al	al	PROPN
admet-2088	1092	7	.	.	PROPN
admet-2088	1092	8	admet	admet	PROPN
admet-2088	1092	9	&	&	CCONJ
admet-2088	1092	10	dmpk	dmpk	PROPN
admet-2088	1092	11	12(1	12(1	PROPN
admet-2088	1092	12	)	)	PUNCT
admet-2088	1092	13	(	(	PUNCT
admet-2088	1092	14	2024	2024	NUM
admet-2088	1092	15	)	)	PUNCT
admet-2088	1092	16	107	107	NUM
admet-2088	1092	17	-	-	SYM
admet-2088	1092	18	150	150	NUM
admet-2088	1092	19	142	142	NUM
admet-2088	1092	20	breast	breast	NOUN
admet-2088	1092	21	cancer	cancer	NOUN
admet-2088	1092	22	.	.	PUNCT
admet-2088	1093	1	international	international	ADJ
admet-2088	1093	2	journal	journal	NOUN
admet-2088	1093	3	of	of	ADP
admet-2088	1093	4	biological	biological	ADJ
admet-2088	1093	5	macromolecules	macromolecule	NOUN
admet-2088	1093	6	172	172	NUM
admet-2088	1093	7	(	(	PUNCT
admet-2088	1093	8	2021	2021	NUM
admet-2088	1093	9	)	)	PUNCT
admet-2088	1093	10	55	55	NUM
admet-2088	1093	11	-	-	SYM
admet-2088	1093	12	65	65	NUM
admet-2088	1093	13	.	.	PUNCT
admet-2088	1093	14	https://doi.org/10.1016/j.ijbiomac.2021.01.037	https://doi.org/10.1016/j.ijbiomac.2021.01.037	NUM
admet-2088	1093	15	.	.	PUNCT
admet-2088	1094	1	[	[	X
admet-2088	1094	2	96	96	NUM
admet-2088	1094	3	]	]	X
admet-2088	1094	4	m.m	m.m	PROPN
admet-2088	1094	5	.	.	PROPN
admet-2088	1094	6	zangeneh	zangeneh	PROPN
admet-2088	1094	7	,	,	PUNCT
admet-2088	1094	8	s.	s.	PROPN
admet-2088	1094	9	bovandi	bovandi	PROPN
admet-2088	1094	10	,	,	PUNCT
admet-2088	1094	11	s.	s.	PROPN
admet-2088	1094	12	gharehyakheh	gharehyakheh	PROPN
admet-2088	1094	13	,	,	PUNCT
admet-2088	1094	14	a.	a.	PROPN
admet-2088	1094	15	zangeneh	zangeneh	PROPN
admet-2088	1094	16	,	,	PUNCT
admet-2088	1094	17	p.	p.	NOUN
admet-2088	1094	18	irani	irani	PROPN
admet-2088	1094	19	.	.	PUNCT
admet-2088	1095	1	green	green	ADJ
admet-2088	1095	2	synthesis	synthesis	NOUN
admet-2088	1095	3	and	and	CCONJ
admet-2088	1095	4	chemical	chemical	NOUN
admet-2088	1095	5	characterization	characterization	NOUN
admet-2088	1095	6	of	of	ADP
admet-2088	1095	7	silver	silver	ADJ
admet-2088	1095	8	nanoparticles	nanoparticle	NOUN
admet-2088	1095	9	obtained	obtain	VERB
admet-2088	1095	10	using	use	VERB
admet-2088	1095	11	allium	allium	NOUN
admet-2088	1095	12	saralicum	saralicum	ADJ
admet-2088	1095	13	aqueous	aqueous	ADJ
admet-2088	1095	14	extract	extract	NOUN
admet-2088	1095	15	and	and	CCONJ
admet-2088	1095	16	survey	survey	NOUN
admet-2088	1095	17	of	of	ADP
admet-2088	1095	18	in	in	ADP
admet-2088	1095	19	vitro	vitro	X
admet-2088	1095	20	antioxidant	antioxidant	ADJ
admet-2088	1095	21	,	,	PUNCT
admet-2088	1095	22	cytotoxic	cytotoxic	ADJ
admet-2088	1095	23	,	,	PUNCT
admet-2088	1095	24	antibacterial	antibacterial	ADJ
admet-2088	1095	25	and	and	CCONJ
admet-2088	1095	26	antifungal	antifungal	ADJ
admet-2088	1095	27	properties	property	NOUN
admet-2088	1095	28	.	.	PUNCT
admet-2088	1096	1	applied	apply	VERB
admet-2088	1096	2	organometallic	organometallic	ADJ
admet-2088	1096	3	chemistry	chemistry	NOUN
admet-2088	1096	4	33	33	NUM
admet-2088	1096	5	(	(	PUNCT
admet-2088	1096	6	2019	2019	NUM
admet-2088	1096	7	)	)	PUNCT
admet-2088	1096	8	e4961	e4961	PROPN
admet-2088	1096	9	.	.	PUNCT
admet-2088	1097	1	https://doi.org/10.1002/aoc.4961	https://doi.org/10.1002/aoc.4961	PROPN
admet-2088	1097	2	.	.	PUNCT
admet-2088	1098	1	[	[	X
admet-2088	1098	2	97	97	NUM
admet-2088	1098	3	]	]	X
admet-2088	1098	4	r.	r.	PROPN
admet-2088	1098	5	manikandan	manikandan	PROPN
admet-2088	1098	6	,	,	PUNCT
admet-2088	1098	7	r.	r.	PROPN
admet-2088	1098	8	anjali	anjali	PROPN
admet-2088	1098	9	,	,	PUNCT
admet-2088	1098	10	m.	m.	PROPN
admet-2088	1098	11	beulaja	beulaja	PROPN
admet-2088	1098	12	,	,	PUNCT
admet-2088	1098	13	n.m	n.m	PROPN
admet-2088	1098	14	.	.	PROPN
admet-2088	1098	15	prabhu	prabhu	PROPN
admet-2088	1098	16	,	,	PUNCT
admet-2088	1098	17	a.	a.	PROPN
admet-2088	1098	18	koodalingam	koodalingam	PROPN
admet-2088	1098	19	,	,	PUNCT
admet-2088	1098	20	g.	g.	PROPN
admet-2088	1098	21	saiprasad	saiprasad	PROPN
admet-2088	1098	22	,	,	PUNCT
admet-2088	1098	23	p.	p.	PROPN
admet-2088	1098	24	chitra	chitra	PROPN
admet-2088	1098	25	,	,	PUNCT
admet-2088	1098	26	m.	m.	NOUN
admet-2088	1098	27	arumugam	arumugam	NOUN
admet-2088	1098	28	.	.	PUNCT
admet-2088	1099	1	synthesis	synthesis	NOUN
admet-2088	1099	2	,	,	PUNCT
admet-2088	1099	3	characterization	characterization	NOUN
admet-2088	1099	4	,	,	PUNCT
admet-2088	1099	5	antiproliferative	antiproliferative	NOUN
admet-2088	1099	6	and	and	CCONJ
admet-2088	1099	7	wound	wound	ADJ
admet-2088	1099	8	healing	healing	NOUN
admet-2088	1099	9	activities	activity	NOUN
admet-2088	1099	10	of	of	ADP
admet-2088	1099	11	silver	silver	ADJ
admet-2088	1099	12	nanoparticles	nanoparticle	NOUN
admet-2088	1099	13	synthesized	synthesize	VERB
admet-2088	1099	14	from	from	ADP
admet-2088	1099	15	caulerpa	caulerpa	PROPN
admet-2088	1099	16	scalpelliformis	scalpelliformis	PROPN
admet-2088	1099	17	.	.	PUNCT
admet-2088	1100	1	process	process	NOUN
admet-2088	1100	2	biochemistry	biochemistry	NOUN
admet-2088	1100	3	79	79	NUM
admet-2088	1100	4	(	(	PUNCT
admet-2088	1100	5	2019	2019	NUM
admet-2088	1100	6	)	)	PUNCT
admet-2088	1100	7	135	135	NUM
admet-2088	1100	8	-	-	SYM
admet-2088	1100	9	141	141	NUM
admet-2088	1100	10	.	.	PUNCT
admet-2088	1101	1	https://doi.org/10.1016/j.procbio.2019.01.013	https://doi.org/10.1016/j.procbio.2019.01.013	X
admet-2088	1101	2	.	.	PUNCT
admet-2088	1102	1	[	[	X
admet-2088	1102	2	98	98	NUM
admet-2088	1102	3	]	]	PUNCT
admet-2088	1102	4	z.	z.	PROPN
admet-2088	1102	5	zhao	zhao	PROPN
admet-2088	1102	6	,	,	PUNCT
admet-2088	1102	7	l.	l.	PROPN
admet-2088	1102	8	fang	fang	PROPN
admet-2088	1102	9	,	,	PUNCT
admet-2088	1102	10	d.	d.	PROPN
admet-2088	1102	11	lv	lv	PROPN
admet-2088	1102	12	,	,	PUNCT
admet-2088	1102	13	l.	l.	PROPN
admet-2088	1102	14	chen	chen	PROPN
admet-2088	1102	15	,	,	PUNCT
admet-2088	1102	16	b.	b.	PROPN
admet-2088	1102	17	zhang	zhang	PROPN
admet-2088	1102	18	,	,	PUNCT
admet-2088	1102	19	d.	d.	PROPN
admet-2088	1102	20	wu	wu	PROPN
admet-2088	1102	21	.	.	PUNCT
admet-2088	1103	1	design	design	NOUN
admet-2088	1103	2	and	and	CCONJ
admet-2088	1103	3	synthesis	synthesis	NOUN
admet-2088	1103	4	of	of	ADP
admet-2088	1103	5	ag	ag	PROPN
admet-2088	1103	6	nps	nps	PROPN
admet-2088	1103	7	/	/	SYM
admet-2088	1103	8	chitosan	chitosan	ADJ
admet-2088	1103	9	-	-	PUNCT
admet-2088	1103	10	starch	starch	NOUN
admet-2088	1103	11	nano	nano	NOUN
admet-2088	1103	12	-	-	PUNCT
admet-2088	1103	13	biocomposite	biocomposite	NOUN
admet-2088	1103	14	as	as	ADP
admet-2088	1103	15	a	a	DET
admet-2088	1103	16	modern	modern	ADJ
admet-2088	1103	17	anti	anti	ADJ
admet-2088	1103	18	-	-	ADJ
admet-2088	1103	19	human	human	ADJ
admet-2088	1103	20	malignant	malignant	ADJ
admet-2088	1103	21	melanoma	melanoma	NOUN
admet-2088	1103	22	drug	drug	NOUN
admet-2088	1103	23	.	.	PUNCT
admet-2088	1104	1	international	international	ADJ
admet-2088	1104	2	journal	journal	NOUN
admet-2088	1104	3	of	of	ADP
admet-2088	1104	4	biological	biological	ADJ
admet-2088	1104	5	macromolecules	macromolecule	NOUN
admet-2088	1104	6	236	236	NUM
admet-2088	1104	7	(	(	PUNCT
admet-2088	1104	8	2023	2023	NUM
admet-2088	1104	9	)	)	PUNCT
admet-2088	1104	10	123823	123823	NUM
admet-2088	1104	11	.	.	PUNCT
admet-2088	1105	1	https://doi.org/10.1016/j.ijbiomac.2023.123823	https://doi.org/10.1016/j.ijbiomac.2023.123823	ADJ
admet-2088	1105	2	.	.	PUNCT
admet-2088	1106	1	[	[	X
admet-2088	1106	2	99	99	NUM
admet-2088	1106	3	]	]	SYM
admet-2088	1106	4	p.m.	p.m.	NOUN
admet-2088	1106	5	patil	patil	PROPN
admet-2088	1106	6	,	,	PUNCT
admet-2088	1106	7	n.	n.	PROPN
admet-2088	1106	8	poddar	poddar	PROPN
admet-2088	1106	9	,	,	PUNCT
admet-2088	1106	10	n.	n.	PROPN
admet-2088	1106	11	parihar	parihar	PROPN
admet-2088	1106	12	,	,	PUNCT
admet-2088	1106	13	s.	s.	PROPN
admet-2088	1106	14	sen	sen	PROPN
admet-2088	1106	15	,	,	PUNCT
admet-2088	1106	16	p.	p.	PROPN
admet-2088	1106	17	mohapatra	mohapatra	PROPN
admet-2088	1106	18	,	,	PUNCT
admet-2088	1106	19	u.s	u.s	PROPN
admet-2088	1106	20	.	.	PROPN
admet-2088	1106	21	murty	murty	PROPN
admet-2088	1106	22	,	,	PUNCT
admet-2088	1106	23	d.b	d.b	PROPN
admet-2088	1106	24	.	.	PROPN
admet-2088	1106	25	pemmaraju	pemmaraju	PROPN
admet-2088	1106	26	.	.	PUNCT
admet-2088	1107	1	optoresponsive	optoresponsive	ADJ
admet-2088	1107	2	pheophorbide	pheophorbide	ADJ
admet-2088	1107	3	-	-	PUNCT
admet-2088	1107	4	silver	silver	NOUN
admet-2088	1107	5	based	base	VERB
admet-2088	1107	6	organometallic	organometallic	ADJ
admet-2088	1107	7	nanomaterials	nanomaterial	NOUN
admet-2088	1107	8	for	for	ADP
admet-2088	1107	9	high	high	ADJ
admet-2088	1107	10	efficacy	efficacy	NOUN
admet-2088	1107	11	multimodal	multimodal	NOUN
admet-2088	1107	12	theranostics	theranostic	NOUN
admet-2088	1107	13	in	in	ADP
admet-2088	1107	14	melanoma	melanoma	NOUN
admet-2088	1107	15	.	.	PUNCT
admet-2088	1108	1	chemical	chemical	PROPN
admet-2088	1108	2	engineering	engineering	PROPN
admet-2088	1108	3	journal	journal	PROPN
admet-2088	1108	4	470	470	NUM
admet-2088	1108	5	(	(	PUNCT
admet-2088	1108	6	2023	2023	NUM
admet-2088	1108	7	)	)	PUNCT
admet-2088	1108	8	144110	144110	NUM
admet-2088	1108	9	.	.	PUNCT
admet-2088	1109	1	https://doi.org/10.1016/j.cej.2023.144110	https://doi.org/10.1016/j.cej.2023.144110	PROPN
admet-2088	1109	2	.	.	PUNCT
admet-2088	1110	1	[	[	X
admet-2088	1110	2	100	100	NUM
admet-2088	1110	3	]	]	X
admet-2088	1110	4	u.	u.	PROPN
admet-2088	1110	5	bunyatova	bunyatova	PROPN
admet-2088	1110	6	,	,	PUNCT
admet-2088	1110	7	m.	m.	PROPN
admet-2088	1110	8	ben	ben	PROPN
admet-2088	1110	9	hammouda	hammouda	PROPN
admet-2088	1110	10	,	,	PUNCT
admet-2088	1110	11	j.	j.	PROPN
admet-2088	1110	12	zhang	zhang	PROPN
admet-2088	1110	13	.	.	PUNCT
admet-2088	1111	1	novel	novel	ADJ
admet-2088	1111	2	light	light	ADV
admet-2088	1111	3	-	-	PUNCT
admet-2088	1111	4	driven	drive	VERB
admet-2088	1111	5	functional	functional	ADJ
admet-2088	1111	6	agnps	agnps	NOUN
admet-2088	1111	7	induce	induce	VERB
admet-2088	1111	8	cancer	cancer	NOUN
admet-2088	1111	9	death	death	NOUN
admet-2088	1111	10	at	at	ADP
admet-2088	1111	11	extra	extra	ADJ
admet-2088	1111	12	low	low	ADJ
admet-2088	1111	13	concentrations	concentration	NOUN
admet-2088	1111	14	.	.	PUNCT
admet-2088	1112	1	scientific	scientific	ADJ
admet-2088	1112	2	report	report	NOUN
admet-2088	1112	3	11	11	NUM
admet-2088	1112	4	(	(	PUNCT
admet-2088	1112	5	2021	2021	NUM
admet-2088	1112	6	)	)	PUNCT
admet-2088	1112	7	13258	13258	NUM
admet-2088	1112	8	.	.	PUNCT
admet-2088	1113	1	https://doi.org/10.1038/s41598021-92689-9	https://doi.org/10.1038/s41598021-92689-9	ADJ
admet-2088	1113	2	.	.	PUNCT
admet-2088	1114	1	[	[	X
admet-2088	1114	2	101	101	NUM
admet-2088	1114	3	]	]	X
admet-2088	1114	4	n.s.v	n.s.v	NOUN
admet-2088	1114	5	.	.	PUNCT
admet-2088	1115	1	capanema	capanema	PROPN
admet-2088	1115	2	,	,	PUNCT
admet-2088	1115	3	i.c	i.c	PROPN
admet-2088	1115	4	.	.	PROPN
admet-2088	1115	5	carvalho	carvalho	PROPN
admet-2088	1115	6	,	,	PUNCT
admet-2088	1115	7	a.a.p	a.a.p	PROPN
admet-2088	1115	8	.	.	PROPN
admet-2088	1115	9	mansur	mansur	PROPN
admet-2088	1115	10	,	,	PUNCT
admet-2088	1115	11	s.m	s.m	PROPN
admet-2088	1115	12	.	.	PROPN
admet-2088	1115	13	carvalho	carvalho	PROPN
admet-2088	1115	14	,	,	PUNCT
admet-2088	1115	15	a.p	a.p	PROPN
admet-2088	1115	16	.	.	PROPN
admet-2088	1115	17	lage	lage	PROPN
admet-2088	1115	18	,	,	PUNCT
admet-2088	1115	19	h.s	h.s	PROPN
admet-2088	1115	20	.	.	PROPN
admet-2088	1115	21	mansur	mansur	PROPN
admet-2088	1115	22	.	.	PUNCT
admet-2088	1116	1	hybrid	hybrid	ADJ
admet-2088	1116	2	hydrogel	hydrogel	NOUN
admet-2088	1116	3	composed	compose	VERB
admet-2088	1116	4	of	of	ADP
admet-2088	1116	5	carboxymethylcellulose	carboxymethylcellulose	PROPN
admet-2088	1116	6	–	–	PUNCT
admet-2088	1116	7	silver	silver	NOUN
admet-2088	1116	8	nanoparticles	nanoparticle	NOUN
admet-2088	1116	9	–	–	PUNCT
admet-2088	1116	10	doxorubicin	doxorubicin	VERB
admet-2088	1116	11	for	for	ADP
admet-2088	1116	12	anticancer	anticancer	NOUN
admet-2088	1116	13	and	and	CCONJ
admet-2088	1116	14	antibacterial	antibacterial	ADJ
admet-2088	1116	15	therapies	therapy	NOUN
admet-2088	1116	16	against	against	ADP
admet-2088	1116	17	melanoma	melanoma	NOUN
admet-2088	1116	18	skin	skin	NOUN
admet-2088	1116	19	cancer	cancer	NOUN
admet-2088	1116	20	cells	cell	NOUN
admet-2088	1116	21	.	.	PUNCT
admet-2088	1117	1	acs	acs	PROPN
admet-2088	1117	2	applied	apply	VERB
admet-2088	1117	3	nano	nano	NOUN
admet-2088	1117	4	materials	material	NOUN
admet-2088	1117	5	2	2	NUM
admet-2088	1117	6	(	(	PUNCT
admet-2088	1117	7	2019	2019	NUM
admet-2088	1117	8	)	)	PUNCT
admet-2088	1117	9	7393	7393	NUM
admet-2088	1117	10	-	-	SYM
admet-2088	1117	11	7408	7408	NUM
admet-2088	1117	12	.	.	PUNCT
admet-2088	1118	1	https://doi.org/10.1021/acsanm.9b01924	https://doi.org/10.1021/acsanm.9b01924	NOUN
admet-2088	1118	2	.	.	PUNCT
admet-2088	1119	1	[	[	X
admet-2088	1119	2	102	102	NUM
admet-2088	1119	3	]	]	X
admet-2088	1119	4	l.m	l.m	PROPN
admet-2088	1119	5	.	.	PROPN
admet-2088	1119	6	valenzuela	valenzuela	PROPN
admet-2088	1119	7	-	-	PUNCT
admet-2088	1119	8	salas	salas	PROPN
admet-2088	1119	9	,	,	PUNCT
admet-2088	1119	10	n.g	n.g	PROPN
admet-2088	1119	11	.	.	PROPN
admet-2088	1119	12	girón	girón	PROPN
admet-2088	1119	13	-	-	PUNCT
admet-2088	1119	14	vázquez	vázquez	NOUN
admet-2088	1119	15	,	,	PUNCT
admet-2088	1119	16	j.c	j.c	PROPN
admet-2088	1119	17	.	.	PROPN
admet-2088	1119	18	garcía	garcía	PROPN
admet-2088	1119	19	-	-	PUNCT
admet-2088	1119	20	ramos	ramos	PROPN
admet-2088	1119	21	,	,	PUNCT
admet-2088	1119	22	o.	o.	PROPN
admet-2088	1119	23	torres	torre	NOUN
admet-2088	1119	24	-	-	PUNCT
admet-2088	1119	25	bugarín	bugarín	NOUN
admet-2088	1119	26	,	,	PUNCT
admet-2088	1119	27	c.	c.	PROPN
admet-2088	1119	28	gómez	gómez	PROPN
admet-2088	1119	29	,	,	PUNCT
admet-2088	1119	30	a.	a.	NOUN
admet-2088	1119	31	pestryakov	pestryakov	PROPN
admet-2088	1119	32	,	,	PUNCT
admet-2088	1119	33	l.j	l.j	PROPN
admet-2088	1119	34	.	.	PROPN
admet-2088	1119	35	villarreal	villarreal	PROPN
admet-2088	1119	36	-	-	PUNCT
admet-2088	1119	37	gómez	gómez	NOUN
admet-2088	1119	38	,	,	PUNCT
admet-2088	1119	39	y.	y.	PROPN
admet-2088	1119	40	toledano	toledano	PROPN
admet-2088	1119	41	-	-	PUNCT
admet-2088	1119	42	magaña	magaña	PROPN
admet-2088	1119	43	,	,	PUNCT
admet-2088	1119	44	n.	n.	PROPN
admet-2088	1119	45	bogdanchikova	bogdanchikova	PROPN
admet-2088	1119	46	.	.	PUNCT
admet-2088	1120	1	antiproliferative	antiproliferative	NOUN
admet-2088	1120	2	and	and	CCONJ
admet-2088	1120	3	antitumour	antitumour	NOUN
admet-2088	1120	4	effect	effect	NOUN
admet-2088	1120	5	of	of	ADP
admet-2088	1120	6	nongenotoxic	nongenotoxic	ADJ
admet-2088	1120	7	silver	silver	ADJ
admet-2088	1120	8	nanoparticles	nanoparticle	NOUN
admet-2088	1120	9	on	on	ADP
admet-2088	1120	10	melanoma	melanoma	NOUN
admet-2088	1120	11	models	model	NOUN
admet-2088	1120	12	.	.	PUNCT
admet-2088	1121	1	oxidative	oxidative	ADJ
admet-2088	1121	2	medicine	medicine	NOUN
admet-2088	1121	3	and	and	CCONJ
admet-2088	1121	4	cellular	cellular	ADJ
admet-2088	1121	5	longevity	longevity	NOUN
admet-2088	1121	6	2019	2019	NUM
admet-2088	1121	7	(	(	PUNCT
admet-2088	1121	8	2019	2019	NUM
admet-2088	1121	9	)	)	PUNCT
admet-2088	1121	10	4528241	4528241	NUM
admet-2088	1121	11	.	.	PUNCT
admet-2088	1122	1	https://doi.org/10.1155/2019/4528241	https://doi.org/10.1155/2019/4528241	PROPN
admet-2088	1122	2	.	.	PUNCT
admet-2088	1123	1	[	[	X
admet-2088	1123	2	103	103	NUM
admet-2088	1123	3	]	]	PUNCT
admet-2088	1123	4	e.g.	e.g.	ADV
admet-2088	1123	5	halevas	halevas	PROPN
admet-2088	1123	6	,	,	PUNCT
admet-2088	1123	7	a.a	a.a	PROPN
admet-2088	1123	8	.	.	PROPN
admet-2088	1123	9	pantazaki	pantazaki	PROPN
admet-2088	1123	10	.	.	PUNCT
admet-2088	1124	1	copper	copper	NOUN
admet-2088	1124	2	nanoparticles	nanoparticle	NOUN
admet-2088	1124	3	as	as	ADP
admet-2088	1124	4	therapeutic	therapeutic	ADJ
admet-2088	1124	5	anticancer	anticancer	NOUN
admet-2088	1124	6	agents	agent	NOUN
admet-2088	1124	7	.	.	PUNCT
admet-2088	1125	1	nanomedicine	nanomedicine	PROPN
admet-2088	1125	2	and	and	CCONJ
admet-2088	1125	3	nanotechnology	nanotechnology	PROPN
admet-2088	1125	4	journal	journal	PROPN
admet-2088	1125	5	2	2	NUM
admet-2088	1125	6	(	(	PUNCT
admet-2088	1125	7	2018	2018	NUM
admet-2088	1125	8	)	)	PUNCT
admet-2088	1125	9	119	119	NUM
admet-2088	1125	10	.	.	PUNCT
admet-2088	1126	1	https://ikee.lib.auth.gr/record/315077/files/halevas%20pantazaki	https://ikee.lib.auth.gr/record/315077/files/halevas%20pantazaki	PROPN
admet-2088	1126	2	.	.	PUNCT
admet-2088	1127	1	[	[	X
admet-2088	1127	2	104	104	X
admet-2088	1127	3	]	]	PUNCT
admet-2088	1127	4	b.	b.	PROPN
admet-2088	1127	5	ma	ma	PROPN
admet-2088	1127	6	,	,	PUNCT
admet-2088	1127	7	s.	s.	PROPN
admet-2088	1127	8	wang	wang	PROPN
admet-2088	1127	9	,	,	PUNCT
admet-2088	1127	10	f.	f.	PROPN
admet-2088	1127	11	liu	liu	PROPN
admet-2088	1127	12	,	,	PUNCT
admet-2088	1127	13	s.	s.	PROPN
admet-2088	1127	14	zhang	zhang	PROPN
admet-2088	1127	15	,	,	PUNCT
admet-2088	1127	16	j.	j.	PROPN
admet-2088	1127	17	duan	duan	PROPN
admet-2088	1127	18	,	,	PUNCT
admet-2088	1127	19	z.	z.	PROPN
admet-2088	1127	20	li	li	PROPN
admet-2088	1127	21	,	,	PUNCT
admet-2088	1127	22	y.	y.	PROPN
admet-2088	1127	23	kong	kong	PROPN
admet-2088	1127	24	,	,	PUNCT
admet-2088	1127	25	y.	y.	PROPN
admet-2088	1127	26	sang	sing	VERB
admet-2088	1127	27	,	,	PUNCT
admet-2088	1127	28	h.	h.	PROPN
admet-2088	1127	29	liu	liu	PROPN
admet-2088	1127	30	,	,	PUNCT
admet-2088	1127	31	w.	w.	PROPN
admet-2088	1127	32	bu	bu	PROPN
admet-2088	1127	33	,	,	PUNCT
admet-2088	1127	34	l.	l.	PROPN
admet-2088	1127	35	li	li	PROPN
admet-2088	1127	36	.	.	PROPN
admet-2088	1127	37	self	self	NOUN
admet-2088	1127	38	-	-	PUNCT
admet-2088	1127	39	assembled	assemble	VERB
admet-2088	1127	40	copper	copper	NOUN
admet-2088	1127	41	-	-	PUNCT
admet-2088	1127	42	amino	amino	ADJ
admet-2088	1127	43	acid	acid	NOUN
admet-2088	1127	44	nanoparticles	nanoparticle	NOUN
admet-2088	1127	45	for	for	ADP
admet-2088	1127	46	in	in	ADP
admet-2088	1127	47	situ	situ	ADJ
admet-2088	1127	48	glutathione	glutathione	NOUN
admet-2088	1127	49	“	"	PUNCT
admet-2088	1127	50	and	and	CCONJ
admet-2088	1127	51	”	"	PUNCT
admet-2088	1127	52	h2o2	h2o2	NOUN
admet-2088	1127	53	sequentially	sequentially	ADV
admet-2088	1127	54	triggered	trigger	VERB
admet-2088	1127	55	chemodynamic	chemodynamic	ADJ
admet-2088	1127	56	therapy	therapy	NOUN
admet-2088	1127	57	.	.	PUNCT
admet-2088	1128	1	journal	journal	PROPN
admet-2088	1128	2	of	of	ADP
admet-2088	1128	3	the	the	DET
admet-2088	1128	4	american	american	PROPN
admet-2088	1128	5	chemical	chemical	PROPN
admet-2088	1128	6	society	society	PROPN
admet-2088	1128	7	141	141	NUM
admet-2088	1128	8	(	(	PUNCT
admet-2088	1128	9	2019	2019	NUM
admet-2088	1128	10	)	)	PUNCT
admet-2088	1128	11	849	849	NUM
admet-2088	1128	12	-	-	SYM
admet-2088	1128	13	857	857	NUM
admet-2088	1128	14	.	.	PUNCT
admet-2088	1129	1	https://doi.org/10.1021/jacs.8b08714	https://doi.org/10.1021/jacs.8b08714	NOUN
admet-2088	1129	2	.	.	PUNCT
admet-2088	1130	1	[	[	X
admet-2088	1130	2	105	105	NUM
admet-2088	1130	3	]	]	X
admet-2088	1130	4	y.	y.	PROPN
admet-2088	1130	5	wang	wang	PROPN
admet-2088	1130	6	,	,	PUNCT
admet-2088	1130	7	w.	w.	PROPN
admet-2088	1130	8	wu	wu	PROPN
admet-2088	1130	9	,	,	PUNCT
admet-2088	1130	10	j.	j.	PROPN
admet-2088	1130	11	liu	liu	PROPN
admet-2088	1130	12	,	,	PUNCT
admet-2088	1130	13	p.n	p.n	PROPN
admet-2088	1130	14	.	.	PROPN
admet-2088	1130	15	manghnani	manghnani	PROPN
admet-2088	1130	16	,	,	PUNCT
admet-2088	1130	17	f.	f.	PROPN
admet-2088	1130	18	hu	hu	PROPN
admet-2088	1130	19	,	,	PUNCT
admet-2088	1130	20	d.	d.	PROPN
admet-2088	1130	21	ma	ma	PROPN
admet-2088	1130	22	,	,	PUNCT
admet-2088	1130	23	c.	c.	PROPN
admet-2088	1130	24	teh	teh	PROPN
admet-2088	1130	25	,	,	PUNCT
admet-2088	1130	26	b.o	b.o	PROPN
admet-2088	1130	27	.	.	PROPN
admet-2088	1130	28	wang	wang	PROPN
admet-2088	1130	29	,	,	PUNCT
admet-2088	1130	30	b.	b.	PROPN
admet-2088	1130	31	liu	liu	PROPN
admet-2088	1130	32	.	.	PUNCT
admet-2088	1131	1	cancer	cancer	NOUN
admet-2088	1131	2	-	-	PUNCT
admet-2088	1131	3	cellactivated	cellactivate	VERB
admet-2088	1131	4	photodynamic	photodynamic	ADJ
admet-2088	1131	5	therapy	therapy	NOUN
admet-2088	1131	6	assisted	assist	VERB
admet-2088	1131	7	by	by	ADP
admet-2088	1131	8	cu(ii)-based	cu(ii)-based	ADJ
admet-2088	1131	9	metalorganic	metalorganic	ADJ
admet-2088	1131	10	framework	framework	NOUN
admet-2088	1131	11	.	.	PUNCT
admet-2088	1132	1	acs	acs	PROPN
admet-2088	1132	2	nano	nano	VERB
admet-2088	1132	3	13	13	NUM
admet-2088	1132	4	(	(	PUNCT
admet-2088	1132	5	2019	2019	NUM
admet-2088	1132	6	)	)	PUNCT
admet-2088	1132	7	6879	6879	NUM
admet-2088	1132	8	-	-	SYM
admet-2088	1132	9	6890	6890	NUM
admet-2088	1132	10	.	.	PUNCT
admet-2088	1133	1	https://doi.org/10.1021/acsnano.9b01665	https://doi.org/10.1021/acsnano.9b01665	NOUN
admet-2088	1133	2	.	.	PUNCT
admet-2088	1134	1	[	[	X
admet-2088	1134	2	106	106	NUM
admet-2088	1134	3	]	]	PUNCT
admet-2088	1134	4	l.-s	l.-	NOUN
admet-2088	1134	5	.	.	PUNCT
admet-2088	1135	1	lin	lin	PROPN
admet-2088	1135	2	,	,	PUNCT
admet-2088	1135	3	t.	t.	PROPN
admet-2088	1135	4	huang	huang	PROPN
admet-2088	1135	5	,	,	PUNCT
admet-2088	1135	6	j.	j.	PROPN
admet-2088	1135	7	song	song	PROPN
admet-2088	1135	8	,	,	PUNCT
admet-2088	1135	9	x.-y	x.-y	PROPN
admet-2088	1135	10	.	.	PUNCT
admet-2088	1136	1	ou	ou	PROPN
admet-2088	1136	2	,	,	PUNCT
admet-2088	1136	3	z.	z.	PROPN
admet-2088	1136	4	wang	wang	PROPN
admet-2088	1136	5	,	,	PUNCT
admet-2088	1136	6	h.	h.	PROPN
admet-2088	1136	7	deng	deng	PROPN
admet-2088	1136	8	,	,	PUNCT
admet-2088	1136	9	r.	r.	PROPN
admet-2088	1136	10	tian	tian	PROPN
admet-2088	1136	11	,	,	PUNCT
admet-2088	1136	12	y.	y.	PROPN
admet-2088	1136	13	liu	liu	PROPN
admet-2088	1136	14	,	,	PUNCT
admet-2088	1136	15	j.-f	j.-f	PROPN
admet-2088	1136	16	.	.	PUNCT
admet-2088	1137	1	wang	wang	PROPN
admet-2088	1137	2	,	,	PUNCT
admet-2088	1137	3	y.	y.	PROPN
admet-2088	1137	4	liu	liu	PROPN
admet-2088	1137	5	,	,	PUNCT
admet-2088	1137	6	g.	g.	PROPN
admet-2088	1137	7	yu	yu	PROPN
admet-2088	1137	8	,	,	PUNCT
admet-2088	1137	9	z.	z.	PROPN
admet-2088	1137	10	zhou	zhou	PROPN
admet-2088	1137	11	,	,	PUNCT
admet-2088	1137	12	s.	s.	PROPN
admet-2088	1137	13	wang	wang	PROPN
admet-2088	1137	14	,	,	PUNCT
admet-2088	1137	15	g.	g.	PROPN
admet-2088	1137	16	niu	niu	PROPN
admet-2088	1137	17	,	,	PUNCT
admet-2088	1137	18	h.-h	h.-h	PROPN
admet-2088	1137	19	.	.	PUNCT
admet-2088	1138	1	yang	yang	PROPN
admet-2088	1138	2	,	,	PUNCT
admet-2088	1138	3	x.	x.	PROPN
admet-2088	1138	4	chen	chen	PROPN
admet-2088	1138	5	.	.	PUNCT
admet-2088	1139	1	synthesis	synthesis	NOUN
admet-2088	1139	2	of	of	ADP
admet-2088	1139	3	copper	copper	NOUN
admet-2088	1139	4	peroxide	peroxide	NOUN
admet-2088	1139	5	nanodots	nanodot	NOUN
admet-2088	1139	6	for	for	ADP
admet-2088	1139	7	h2o2	h2o2	NOUN
admet-2088	1139	8	selfsupplying	selfsupplye	VERB
admet-2088	1139	9	chemodynamic	chemodynamic	PROPN
admet-2088	1139	10	therapy	therapy	NOUN
admet-2088	1139	11	.	.	PUNCT
admet-2088	1140	1	journal	journal	PROPN
admet-2088	1140	2	of	of	ADP
admet-2088	1140	3	the	the	DET
admet-2088	1140	4	american	american	PROPN
admet-2088	1140	5	chemical	chemical	PROPN
admet-2088	1140	6	society	society	PROPN
admet-2088	1140	7	141	141	NUM
admet-2088	1140	8	(	(	PUNCT
admet-2088	1140	9	2019	2019	NUM
admet-2088	1140	10	)	)	PUNCT
admet-2088	1140	11	9937	9937	NUM
admet-2088	1140	12	-	-	SYM
admet-2088	1140	13	9945	9945	NUM
admet-2088	1140	14	.	.	PUNCT
admet-2088	1141	1	https://doi.org/10.1021/jacs.9b03457	https://doi.org/10.1021/jacs.9b03457	NOUN
admet-2088	1141	2	.	.	PUNCT
admet-2088	1142	1	[	[	X
admet-2088	1142	2	107	107	NUM
admet-2088	1142	3	]	]	PUNCT
admet-2088	1142	4	h.	h.	NOUN
admet-2088	1142	5	song	song	PROPN
admet-2088	1142	6	,	,	PUNCT
admet-2088	1142	7	q.	q.	PROPN
admet-2088	1142	8	xu	xu	PROPN
admet-2088	1142	9	,	,	PUNCT
admet-2088	1142	10	y.	y.	PROPN
admet-2088	1142	11	zhu	zhu	PROPN
admet-2088	1142	12	,	,	PUNCT
admet-2088	1142	13	s.	s.	PROPN
admet-2088	1142	14	zhu	zhu	PROPN
admet-2088	1142	15	,	,	PUNCT
admet-2088	1142	16	h.	h.	PROPN
admet-2088	1142	17	tang	tang	PROPN
admet-2088	1142	18	,	,	PUNCT
admet-2088	1142	19	y.	y.	PROPN
admet-2088	1142	20	wang	wang	PROPN
admet-2088	1142	21	,	,	PUNCT
admet-2088	1142	22	h.	h.	PROPN
admet-2088	1142	23	ren	ren	PROPN
admet-2088	1142	24	,	,	PUNCT
admet-2088	1142	25	p.	p.	NOUN
admet-2088	1142	26	zhao	zhao	PROPN
admet-2088	1142	27	,	,	PUNCT
admet-2088	1142	28	z.	z.	PROPN
admet-2088	1142	29	qi	qi	PROPN
admet-2088	1142	30	,	,	PUNCT
admet-2088	1142	31	s.	s.	PROPN
admet-2088	1142	32	zhao	zhao	PROPN
admet-2088	1142	33	.	.	PUNCT
admet-2088	1143	1	serum	serum	NOUN
admet-2088	1143	2	adsorption	adsorption	NOUN
admet-2088	1143	3	,	,	PUNCT
admet-2088	1143	4	cellular	cellular	ADJ
admet-2088	1143	5	internalization	internalization	NOUN
admet-2088	1143	6	and	and	CCONJ
admet-2088	1143	7	consequent	consequent	ADJ
admet-2088	1143	8	impact	impact	NOUN
admet-2088	1143	9	of	of	ADP
admet-2088	1143	10	cuprous	cuprous	ADJ
admet-2088	1143	11	oxide	oxide	NOUN
admet-2088	1143	12	nanoparticles	nanoparticle	NOUN
admet-2088	1143	13	on	on	ADP
admet-2088	1143	14	uveal	uveal	ADJ
admet-2088	1143	15	melanoma	melanoma	NOUN
admet-2088	1143	16	cells	cell	NOUN
admet-2088	1143	17	:	:	PUNCT
admet-2088	1143	18	implications	implication	NOUN
admet-2088	1143	19	for	for	ADP
admet-2088	1143	20	cancer	cancer	NOUN
admet-2088	1143	21	therapy	therapy	NOUN
admet-2088	1143	22	.	.	PUNCT
admet-2088	1144	1	nanomedicine	nanomedicine	NOUN
admet-2088	1144	2	10	10	NUM
admet-2088	1144	3	(	(	PUNCT
admet-2088	1144	4	2015	2015	NUM
admet-2088	1144	5	)	)	PUNCT
admet-2088	1144	6	3547	3547	NUM
admet-2088	1144	7	-	-	SYM
admet-2088	1144	8	3562	3562	NUM
admet-2088	1144	9	.	.	PUNCT
admet-2088	1145	1	https://doi.org/10.2217/nnm.15.178	https://doi.org/10.2217/nnm.15.178	NOUN
admet-2088	1145	2	.	.	PUNCT
admet-2088	1146	1	[	[	X
admet-2088	1146	2	108	108	NUM
admet-2088	1146	3	]	]	PUNCT
admet-2088	1146	4	m.	m.	NOUN
admet-2088	1146	5	huo	huo	PROPN
admet-2088	1146	6	,	,	PUNCT
admet-2088	1146	7	l.	l.	PROPN
admet-2088	1146	8	wang	wang	PROPN
admet-2088	1146	9	,	,	PUNCT
admet-2088	1146	10	y.	y.	PROPN
admet-2088	1146	11	wang	wang	PROPN
admet-2088	1146	12	,	,	PUNCT
admet-2088	1146	13	y.	y.	PROPN
admet-2088	1146	14	chen	chen	PROPN
admet-2088	1146	15	,	,	PUNCT
admet-2088	1146	16	j.	j.	PROPN
admet-2088	1146	17	shi	shi	PROPN
admet-2088	1146	18	,	,	PUNCT
admet-2088	1146	19	nanocatalytic	nanocatalytic	ADJ
admet-2088	1146	20	tumor	tumor	NOUN
admet-2088	1146	21	therapy	therapy	NOUN
admet-2088	1146	22	by	by	ADP
admet-2088	1146	23	single	single	ADJ
admet-2088	1146	24	-	-	PUNCT
admet-2088	1146	25	atom	atom	NOUN
admet-2088	1146	26	catalysts	catalyst	NOUN
admet-2088	1146	27	.	.	PUNCT
admet-2088	1147	1	acs	acs	PROPN
admet-2088	1147	2	nano	nano	VERB
admet-2088	1147	3	13	13	NUM
admet-2088	1147	4	(	(	PUNCT
admet-2088	1147	5	2019	2019	NUM
admet-2088	1147	6	)	)	PUNCT
admet-2088	1147	7	2643	2643	NUM
admet-2088	1147	8	-	-	SYM
admet-2088	1147	9	2653	2653	NUM
admet-2088	1147	10	.	.	PUNCT
admet-2088	1148	1	https://doi.org/10.1021/acsnano.9b00457	https://doi.org/10.1021/acsnano.9b00457	NOUN
admet-2088	1148	2	.	.	PUNCT
admet-2088	1149	1	[	[	X
admet-2088	1149	2	109	109	NUM
admet-2088	1149	3	]	]	PUNCT
admet-2088	1149	4	b.	b.	PROPN
admet-2088	1149	5	yang	yang	PROPN
admet-2088	1149	6	,	,	PUNCT
admet-2088	1149	7	y.	y.	PROPN
admet-2088	1149	8	chen	chen	PROPN
admet-2088	1149	9	,	,	PUNCT
admet-2088	1149	10	j.	j.	PROPN
admet-2088	1149	11	shi	shi	PROPN
admet-2088	1149	12	,	,	PUNCT
admet-2088	1149	13	nanocatalytic	nanocatalytic	ADJ
admet-2088	1149	14	medicine	medicine	NOUN
admet-2088	1149	15	.	.	PUNCT
admet-2088	1150	1	advanced	advanced	ADJ
admet-2088	1150	2	materials	material	NOUN
admet-2088	1150	3	31	31	NUM
admet-2088	1150	4	(	(	PUNCT
admet-2088	1150	5	2019	2019	NUM
admet-2088	1150	6	)	)	PUNCT
admet-2088	1150	7	e1901778	e1901778	PROPN
admet-2088	1150	8	.	.	PUNCT
admet-2088	1150	9	https://doi.org/10.1002/adma.201901778	https://doi.org/10.1002/adma.201901778	NOUN
admet-2088	1150	10	.	.	PUNCT
admet-2088	1151	1	https://doi.org/10.1016/j.ijbiomac.2021.01.037	https://doi.org/10.1016/j.ijbiomac.2021.01.037	NUM
admet-2088	1151	2	https://doi.org/10.1002/aoc.4961	https://doi.org/10.1002/aoc.4961	ADJ
admet-2088	1151	3	https://doi.org/10.1016/j.procbio.2019.01.013	https://doi.org/10.1016/j.procbio.2019.01.013	NOUN
admet-2088	1151	4	https://doi.org/10.1016/j.ijbiomac.2023.123823	https://doi.org/10.1016/j.ijbiomac.2023.123823	ADJ
admet-2088	1151	5	https://doi.org/10.1016/j.cej.2023.144110	https://doi.org/10.1016/j.cej.2023.144110	PROPN
admet-2088	1151	6	https://doi.org/10.1038/s41598-021-92689-9	https://doi.org/10.1038/s41598-021-92689-9	X
admet-2088	1151	7	https://doi.org/10.1038/s41598-021-92689-9	https://doi.org/10.1038/s41598-021-92689-9	NUM
admet-2088	1151	8	https://doi.org/10.1021/acsanm.9b01924	https://doi.org/10.1021/acsanm.9b01924	PROPN
admet-2088	1151	9	https://doi.org/10.1155/2019/4528241	https://doi.org/10.1155/2019/4528241	PROPN
admet-2088	1151	10	https://ikee.lib.auth.gr/record/315077/files/halevas%20pantazaki	https://ikee.lib.auth.gr/record/315077/files/halevas%20pantazaki	VERB
admet-2088	1151	11	https://doi.org/10.1021/jacs.8b08714	https://doi.org/10.1021/jacs.8b08714	NOUN
admet-2088	1151	12	https://doi.org/10.1021/acsnano.9b01665	https://doi.org/10.1021/acsnano.9b01665	ADJ
admet-2088	1151	13	https://doi.org/10.1021/jacs.9b03457	https://doi.org/10.1021/jacs.9b03457	PROPN
admet-2088	1151	14	https://doi.org/10.2217/nnm.15.178	https://doi.org/10.2217/nnm.15.178	PROPN
admet-2088	1151	15	https://doi.org/10.1021/acsnano.9b00457	https://doi.org/10.1021/acsnano.9b00457	PROPN
admet-2088	1151	16	https://doi.org/10.1002/adma.201901778	https://doi.org/10.1002/adma.201901778	NUM
admet-2088	1151	17	admet	admet	PROPN
admet-2088	1151	18	&	&	CCONJ
admet-2088	1151	19	dmpk	dmpk	PROPN
admet-2088	1151	20	12(1	12(1	PROPN
admet-2088	1151	21	)	)	PUNCT
admet-2088	1151	22	(	(	PUNCT
admet-2088	1151	23	2024	2024	NUM
admet-2088	1151	24	)	)	PUNCT
admet-2088	1151	25	107	107	NUM
admet-2088	1151	26	-	-	SYM
admet-2088	1151	27	150	150	NUM
admet-2088	1151	28	nanomaterial	nanomaterial	NOUN
admet-2088	1151	29	-	-	PUNCT
admet-2088	1151	30	based	base	VERB
admet-2088	1151	31	drug	drug	NOUN
admet-2088	1151	32	delivery	delivery	NOUN
admet-2088	1151	33	systems	system	NOUN
admet-2088	1151	34	for	for	ADP
admet-2088	1151	35	melanoma	melanoma	NOUN
admet-2088	1151	36	therapy	therapy	NOUN
admet-2088	1151	37	doi	doi	NOUN
admet-2088	1151	38	:	:	PUNCT
admet-2088	1151	39	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	1151	40	143	143	NUM
admet-2088	1151	41	[	[	X
admet-2088	1151	42	110	110	NUM
admet-2088	1151	43	]	]	PUNCT
admet-2088	1151	44	t.	t.	NOUN
admet-2088	1151	45	fang	fang	PROPN
admet-2088	1151	46	,	,	PUNCT
admet-2088	1151	47	s.	s.	PROPN
admet-2088	1151	48	ma	ma	PROPN
admet-2088	1151	49	,	,	PUNCT
admet-2088	1151	50	y.	y.	PROPN
admet-2088	1151	51	wei	wei	PROPN
admet-2088	1151	52	,	,	PUNCT
admet-2088	1151	53	j.	j.	PROPN
admet-2088	1151	54	yang	yang	PROPN
admet-2088	1151	55	,	,	PUNCT
admet-2088	1151	56	j.	j.	PROPN
admet-2088	1151	57	zhang	zhang	PROPN
admet-2088	1151	58	,	,	PUNCT
admet-2088	1151	59	q.	q.	PROPN
admet-2088	1151	60	shen	shen	PROPN
admet-2088	1151	61	.	.	PUNCT
admet-2088	1152	1	catalytic	catalytic	ADJ
admet-2088	1152	2	immunotherapy	immunotherapy	NOUN
admet-2088	1152	3	-	-	ADJ
admet-2088	1152	4	photothermal	photothermal	ADJ
admet-2088	1152	5	therapy	therapy	NOUN
admet-2088	1152	6	combination	combination	NOUN
admet-2088	1152	7	for	for	ADP
admet-2088	1152	8	melanoma	melanoma	NOUN
admet-2088	1152	9	by	by	ADP
admet-2088	1152	10	ferroptosis	ferroptosis	NOUN
admet-2088	1152	11	-	-	PUNCT
admet-2088	1152	12	activating	activate	VERB
admet-2088	1152	13	vaccine	vaccine	NOUN
admet-2088	1152	14	based	base	VERB
admet-2088	1152	15	on	on	ADP
admet-2088	1152	16	artificial	artificial	ADJ
admet-2088	1152	17	nanoenzyme	nanoenzyme	NOUN
admet-2088	1152	18	.	.	PUNCT
admet-2088	1153	1	materials	material	NOUN
admet-2088	1153	2	today	today	NOUN
admet-2088	1153	3	chemistry	chemistry	NOUN
admet-2088	1153	4	27	27	NUM
admet-2088	1153	5	(	(	PUNCT
admet-2088	1153	6	2023	2023	NUM
admet-2088	1153	7	)	)	PUNCT
admet-2088	1153	8	101308	101308	NUM
admet-2088	1153	9	.	.	PUNCT
admet-2088	1154	1	https://doi.org/10.1016/j.mtchem.2022.101308	https://doi.org/10.1016/j.mtchem.2022.101308	NOUN
admet-2088	1154	2	.	.	PUNCT
admet-2088	1155	1	[	[	X
admet-2088	1155	2	111	111	NUM
admet-2088	1155	3	]	]	PUNCT
admet-2088	1155	4	y.	y.	PROPN
admet-2088	1155	5	liu	liu	PROPN
admet-2088	1155	6	,	,	PUNCT
admet-2088	1155	7	c.-f	c.-f	NOUN
admet-2088	1155	8	.	.	PUNCT
admet-2088	1156	1	xu	xu	PROPN
admet-2088	1156	2	,	,	PUNCT
admet-2088	1156	3	s.	s.	PROPN
admet-2088	1156	4	iqbal	iqbal	PROPN
admet-2088	1156	5	,	,	PUNCT
admet-2088	1156	6	x.-z	x.-z	PROPN
admet-2088	1156	7	.	.	PUNCT
admet-2088	1157	1	yang	yang	PROPN
admet-2088	1157	2	,	,	PUNCT
admet-2088	1157	3	j.	j.	PROPN
admet-2088	1157	4	wang	wang	PROPN
admet-2088	1157	5	.	.	PUNCT
admet-2088	1158	1	responsive	responsive	ADJ
admet-2088	1158	2	nanocarriers	nanocarrier	NOUN
admet-2088	1158	3	as	as	ADP
admet-2088	1158	4	an	an	DET
admet-2088	1158	5	emerging	emerge	VERB
admet-2088	1158	6	platform	platform	NOUN
admet-2088	1158	7	for	for	ADP
admet-2088	1158	8	cascaded	cascade	VERB
admet-2088	1158	9	delivery	delivery	NOUN
admet-2088	1158	10	of	of	ADP
admet-2088	1158	11	nucleic	nucleic	ADJ
admet-2088	1158	12	acids	acid	NOUN
admet-2088	1158	13	to	to	ADP
admet-2088	1158	14	cancer	cancer	NOUN
admet-2088	1158	15	.	.	PUNCT
admet-2088	1159	1	advanced	advanced	ADJ
admet-2088	1159	2	drug	drug	NOUN
admet-2088	1159	3	delivery	delivery	NOUN
admet-2088	1159	4	reviews	review	VERB
admet-2088	1159	5	115	115	NUM
admet-2088	1159	6	(	(	PUNCT
admet-2088	1159	7	2017	2017	NUM
admet-2088	1159	8	)	)	PUNCT
admet-2088	1159	9	98	98	NUM
admet-2088	1159	10	-	-	SYM
admet-2088	1159	11	114	114	NUM
admet-2088	1159	12	.	.	PUNCT
admet-2088	1160	1	https://doi.org/10.1016/j.addr.2017.03.004	https://doi.org/10.1016/j.addr.2017.03.004	PROPN
admet-2088	1160	2	.	.	PUNCT
admet-2088	1161	1	[	[	X
admet-2088	1161	2	112	112	NUM
admet-2088	1161	3	]	]	PUNCT
admet-2088	1161	4	j.	j.	PROPN
admet-2088	1161	5	chen	chen	PROPN
admet-2088	1161	6	,	,	PUNCT
admet-2088	1161	7	y.	y.	PROPN
admet-2088	1161	8	zhu	zhu	PROPN
admet-2088	1161	9	,	,	PUNCT
admet-2088	1161	10	s.	s.	PROPN
admet-2088	1161	11	kaskel	kaskel	PROPN
admet-2088	1161	12	.	.	PUNCT
admet-2088	1162	1	porphyrin	porphyrin	NOUN
admet-2088	1162	2	-	-	PUNCT
admet-2088	1162	3	based	base	VERB
admet-2088	1162	4	metal	metal	NOUN
admet-2088	1162	5	-	-	PUNCT
admet-2088	1162	6	organic	organic	ADJ
admet-2088	1162	7	frameworks	framework	NOUN
admet-2088	1162	8	for	for	ADP
admet-2088	1162	9	biomedical	biomedical	ADJ
admet-2088	1162	10	applications	application	NOUN
admet-2088	1162	11	.	.	PUNCT
admet-2088	1163	1	angewandte	angewandte	PROPN
admet-2088	1163	2	chemie	chemie	PROPN
admet-2088	1163	3	international	international	PROPN
admet-2088	1163	4	edition	edition	PROPN
admet-2088	1163	5	60	60	NUM
admet-2088	1163	6	(	(	PUNCT
admet-2088	1163	7	2021	2021	NUM
admet-2088	1163	8	)	)	PUNCT
admet-2088	1163	9	5010	5010	NUM
admet-2088	1163	10	-	-	SYM
admet-2088	1163	11	5035	5035	NUM
admet-2088	1163	12	.	.	PUNCT
admet-2088	1164	1	https://doi.org/10.1002/anie.201909880	https://doi.org/10.1002/anie.201909880	ADJ
admet-2088	1164	2	.	.	PUNCT
admet-2088	1165	1	[	[	X
admet-2088	1165	2	113	113	NUM
admet-2088	1165	3	]	]	PUNCT
admet-2088	1165	4	s.	s.	PROPN
admet-2088	1165	5	mukherjee	mukherjee	PROPN
admet-2088	1165	6	,	,	PUNCT
admet-2088	1165	7	r.	r.	PROPN
admet-2088	1165	8	kotcherlakota	kotcherlakota	PROPN
admet-2088	1165	9	,	,	PUNCT
admet-2088	1165	10	s.	s.	PROPN
admet-2088	1165	11	haque	haque	PROPN
admet-2088	1165	12	,	,	PUNCT
admet-2088	1165	13	s.	s.	PROPN
admet-2088	1165	14	haque	haque	PROPN
admet-2088	1165	15	,	,	PUNCT
admet-2088	1165	16	d.	d.	PROPN
admet-2088	1165	17	bhattacharya	bhattacharya	PROPN
admet-2088	1165	18	,	,	PUNCT
admet-2088	1165	19	j.m	j.m	PROPN
admet-2088	1165	20	.	.	PROPN
admet-2088	1165	21	kumar	kumar	PROPN
admet-2088	1165	22	,	,	PUNCT
admet-2088	1165	23	s.	s.	PROPN
admet-2088	1165	24	chakravarty	chakravarty	PROPN
admet-2088	1165	25	,	,	PUNCT
admet-2088	1165	26	c.r	c.r	PROPN
admet-2088	1165	27	.	.	PROPN
admet-2088	1165	28	patra	patra	PROPN
admet-2088	1165	29	.	.	PROPN
admet-2088	1165	30	improved	improved	ADJ
admet-2088	1165	31	delivery	delivery	NOUN
admet-2088	1165	32	of	of	ADP
admet-2088	1165	33	doxorubicin	doxorubicin	PROPN
admet-2088	1165	34	using	use	VERB
admet-2088	1165	35	rationally	rationally	ADV
admet-2088	1165	36	designed	design	VERB
admet-2088	1165	37	pegylated	pegylated	ADJ
admet-2088	1165	38	platinum	platinum	NOUN
admet-2088	1165	39	nanoparticles	nanoparticle	NOUN
admet-2088	1165	40	for	for	ADP
admet-2088	1165	41	the	the	DET
admet-2088	1165	42	treatment	treatment	NOUN
admet-2088	1165	43	of	of	ADP
admet-2088	1165	44	melanoma	melanoma	NOUN
admet-2088	1165	45	.	.	PUNCT
admet-2088	1166	1	material	material	PROPN
admet-2088	1166	2	sciences	sciences	PROPN
admet-2088	1166	3	&	&	CCONJ
admet-2088	1166	4	engineering	engineering	PROPN
admet-2088	1166	5	c	c	PROPN
admet-2088	1166	6	108	108	NUM
admet-2088	1166	7	(	(	PUNCT
admet-2088	1166	8	2020	2020	NUM
admet-2088	1166	9	)	)	PUNCT
admet-2088	1166	10	110375	110375	NUM
admet-2088	1166	11	.	.	PUNCT
admet-2088	1167	1	https://doi.org/10.1016/j.msec.2019.110375	https://doi.org/10.1016/j.msec.2019.110375	PROPN
admet-2088	1167	2	.	.	PUNCT
admet-2088	1168	1	[	[	X
admet-2088	1168	2	114	114	NUM
admet-2088	1168	3	]	]	X
admet-2088	1168	4	w.l	w.l	PROPN
admet-2088	1168	5	.	.	PROPN
admet-2088	1168	6	xue	xue	PROPN
admet-2088	1168	7	,	,	PUNCT
admet-2088	1168	8	x.n	x.n	PROPN
admet-2088	1168	9	.	.	PUNCT
admet-2088	1168	10	zhao	zhao	PROPN
admet-2088	1168	11	,	,	PUNCT
admet-2088	1168	12	d.w	d.w	PROPN
admet-2088	1168	13	.	.	PROPN
admet-2088	1169	1	gao	gao	PROPN
admet-2088	1169	2	,	,	PUNCT
admet-2088	1169	3	f.m	f.m	PROPN
admet-2088	1169	4	.	.	PROPN
admet-2088	1169	5	gao	gao	PROPN
admet-2088	1169	6	,	,	PUNCT
admet-2088	1169	7	z.	z.	PROPN
admet-2088	1169	8	wang	wang	PROPN
admet-2088	1169	9	,	,	PUNCT
admet-2088	1169	10	y.p	y.p	PROPN
admet-2088	1169	11	.	.	PROPN
admet-2088	1169	12	liu	liu	PROPN
admet-2088	1169	13	,	,	PUNCT
admet-2088	1169	14	x.	x.	PROPN
admet-2088	1169	15	zhang	zhang	PROPN
admet-2088	1169	16	,	,	PUNCT
admet-2088	1169	17	l.	l.	PROPN
admet-2088	1169	18	luoa	luoa	PROPN
admet-2088	1169	19	,	,	PUNCT
admet-2088	1169	20	z.	z.	PROPN
admet-2088	1169	21	liua	liua	PROPN
admet-2088	1169	22	.	.	PUNCT
admet-2088	1170	1	octreotide	octreotide	NOUN
admet-2088	1170	2	acetate	acetate	NOUN
admet-2088	1170	3	-	-	PUNCT
admet-2088	1170	4	templated	template	VERB
admet-2088	1170	5	self	self	NOUN
admet-2088	1170	6	-	-	PUNCT
admet-2088	1170	7	assembly	assembly	NOUN
admet-2088	1170	8	pt	pt	NOUN
admet-2088	1170	9	nanoparticles	nanoparticle	NOUN
admet-2088	1170	10	and	and	CCONJ
admet-2088	1170	11	their	their	PRON
admet-2088	1170	12	anti	anti	ADJ
admet-2088	1170	13	-	-	ADJ
admet-2088	1170	14	tumor	tumor	ADJ
admet-2088	1170	15	efficacy	efficacy	NOUN
admet-2088	1170	16	.	.	PUNCT
admet-2088	1171	1	rsc	rsc	PROPN
admet-2088	1171	2	advances	advance	VERB
admet-2088	1171	3	5	5	NUM
admet-2088	1171	4	(	(	PUNCT
admet-2088	1171	5	2015	2015	NUM
admet-2088	1171	6	)	)	PUNCT
admet-2088	1171	7	42186	42186	NUM
admet-2088	1171	8	-	-	SYM
admet-2088	1171	9	42192	42192	NUM
admet-2088	1171	10	.	.	PUNCT
admet-2088	1172	1	https://doi.org/10.1039/c5ra02921j	https://doi.org/10.1039/c5ra02921j	PROPN
admet-2088	1172	2	.	.	PUNCT
admet-2088	1173	1	[	[	X
admet-2088	1173	2	115	115	NUM
admet-2088	1173	3	]	]	X
admet-2088	1173	4	p.h	p.h	PROPN
admet-2088	1173	5	.	.	PROPN
admet-2088	1173	6	ling	ling	PROPN
admet-2088	1173	7	,	,	PUNCT
admet-2088	1173	8	j.p	j.p	PROPN
admet-2088	1173	9	.	.	PROPN
admet-2088	1173	10	lei	lei	PROPN
admet-2088	1173	11	,	,	PUNCT
admet-2088	1173	12	l.	l.	PROPN
admet-2088	1173	13	jia	jia	PROPN
admet-2088	1173	14	,	,	PUNCT
admet-2088	1173	15	h.x	h.x	PROPN
admet-2088	1173	16	.	.	PROPN
admet-2088	1173	17	ju	ju	PROPN
admet-2088	1173	18	.	.	PUNCT
admet-2088	1173	19	platinum	platinum	NOUN
admet-2088	1173	20	nanoparticles	nanoparticle	NOUN
admet-2088	1173	21	encapsulated	encapsulate	VERB
admet-2088	1173	22	metal	metal	NOUN
admet-2088	1173	23	-	-	PUNCT
admet-2088	1173	24	organic	organic	ADJ
admet-2088	1173	25	frameworks	framework	NOUN
admet-2088	1173	26	for	for	ADP
admet-2088	1173	27	the	the	DET
admet-2088	1173	28	electrochemical	electrochemical	ADJ
admet-2088	1173	29	detection	detection	NOUN
admet-2088	1173	30	of	of	ADP
admet-2088	1173	31	telomerase	telomerase	NOUN
admet-2088	1173	32	activity	activity	NOUN
admet-2088	1173	33	.	.	PUNCT
admet-2088	1174	1	chemical	chemical	NOUN
admet-2088	1174	2	communications	communication	NOUN
admet-2088	1174	3	52	52	NUM
admet-2088	1174	4	(	(	PUNCT
admet-2088	1174	5	2016	2016	NUM
admet-2088	1174	6	)	)	PUNCT
admet-2088	1174	7	12261229	12261229	NUM
admet-2088	1174	8	.	.	PUNCT
admet-2088	1175	1	https://doi.org/10.1039/c5cc08418k	https://doi.org/10.1039/c5cc08418k	PROPN
admet-2088	1175	2	.	.	PUNCT
admet-2088	1176	1	[	[	X
admet-2088	1176	2	116	116	X
admet-2088	1176	3	]	]	X
admet-2088	1176	4	s.	s.	PROPN
admet-2088	1176	5	dasari	dasari	PROPN
admet-2088	1176	6	,	,	PUNCT
admet-2088	1176	7	p.b	p.b	PROPN
admet-2088	1176	8	.	.	PROPN
admet-2088	1176	9	tchounwo	tchounwo	PROPN
admet-2088	1176	10	.	.	PROPN
admet-2088	1176	11	cisplatin	cisplatin	NOUN
admet-2088	1176	12	in	in	ADP
admet-2088	1176	13	cancer	cancer	NOUN
admet-2088	1176	14	therapy	therapy	NOUN
admet-2088	1176	15	:	:	PUNCT
admet-2088	1176	16	molecular	molecular	ADJ
admet-2088	1176	17	mechanisms	mechanism	NOUN
admet-2088	1176	18	of	of	ADP
admet-2088	1176	19	action	action	NOUN
admet-2088	1176	20	.	.	PUNCT
admet-2088	1177	1	european	european	PROPN
admet-2088	1177	2	journal	journal	PROPN
admet-2088	1177	3	of	of	ADP
admet-2088	1177	4	pharmacology	pharmacology	NOUN
admet-2088	1177	5	740	740	NUM
admet-2088	1177	6	(	(	PUNCT
admet-2088	1177	7	2014	2014	NUM
admet-2088	1177	8	)	)	PUNCT
admet-2088	1177	9	364	364	NUM
admet-2088	1177	10	-	-	SYM
admet-2088	1177	11	378	378	NUM
admet-2088	1177	12	.	.	PUNCT
admet-2088	1178	1	https://doi.org/10.1016/j.ejphar.2014.07.025	https://doi.org/10.1016/j.ejphar.2014.07.025	PROPN
admet-2088	1178	2	.	.	PUNCT
admet-2088	1179	1	[	[	X
admet-2088	1179	2	117	117	NUM
admet-2088	1179	3	]	]	X
admet-2088	1179	4	t.c	t.c	PROPN
admet-2088	1179	5	.	.	PROPN
admet-2088	1179	6	johnstone	johnstone	PROPN
admet-2088	1179	7	,	,	PUNCT
admet-2088	1179	8	g.y	g.y	PROPN
admet-2088	1179	9	.	.	PROPN
admet-2088	1179	10	park	park	PROPN
admet-2088	1179	11	,	,	PUNCT
admet-2088	1179	12	s.j	s.j	PROPN
admet-2088	1179	13	.	.	PROPN
admet-2088	1179	14	lippard	lippard	PROPN
admet-2088	1179	15	.	.	PUNCT
admet-2088	1180	1	understanding	understanding	NOUN
admet-2088	1180	2	and	and	CCONJ
admet-2088	1180	3	improving	improve	VERB
admet-2088	1180	4	platinum	platinum	NOUN
admet-2088	1180	5	anticancer	anticancer	NOUN
admet-2088	1180	6	drugsphenanthriplatin	drugsphenanthriplatin	PROPN
admet-2088	1180	7	.	.	PUNCT
admet-2088	1181	1	anticancer	anticancer	NOUN
admet-2088	1181	2	research	research	NOUN
admet-2088	1181	3	34	34	NUM
admet-2088	1181	4	(	(	PUNCT
admet-2088	1181	5	2014	2014	NUM
admet-2088	1181	6	)	)	PUNCT
admet-2088	1181	7	471	471	NUM
admet-2088	1181	8	-	-	SYM
admet-2088	1181	9	476	476	NUM
admet-2088	1181	10	.	.	PUNCT
admet-2088	1182	1	https://pubmed.ncbi.nlm.nih.gov/24403503/.	https://pubmed.ncbi.nlm.nih.gov/24403503/.	PROPN
admet-2088	1182	2	[	[	X
admet-2088	1182	3	118	118	NUM
admet-2088	1182	4	]	]	X
admet-2088	1182	5	d.	d.	PROPN
admet-2088	1182	6	pedone	pedone	PROPN
admet-2088	1182	7	,	,	PUNCT
admet-2088	1182	8	m.	m.	NOUN
admet-2088	1182	9	moglianetti	moglianetti	PROPN
admet-2088	1182	10	,	,	PUNCT
admet-2088	1182	11	g.	g.	PROPN
admet-2088	1182	12	bardi	bardi	PROPN
admet-2088	1182	13	,	,	PUNCT
admet-2088	1182	14	p.p	p.p	PROPN
admet-2088	1182	15	.	.	PROPN
admet-2088	1182	16	pompa	pompa	PROPN
admet-2088	1182	17	,	,	PUNCT
admet-2088	1182	18	e.	e.	PROPN
admet-2088	1182	19	de	de	PROPN
admet-2088	1182	20	luca	luca	PROPN
admet-2088	1182	21	.	.	PUNCT
admet-2088	1183	1	platinum	platinum	NOUN
admet-2088	1183	2	nanoparticles	nanoparticle	NOUN
admet-2088	1183	3	in	in	ADP
admet-2088	1183	4	nanobiomedicine	nanobiomedicine	PROPN
admet-2088	1183	5	.	.	PUNCT
admet-2088	1184	1	chemical	chemical	PROPN
admet-2088	1184	2	society	society	PROPN
admet-2088	1184	3	reviews	reviews	PROPN
admet-2088	1184	4	journal	journal	NOUN
admet-2088	1184	5	46	46	NUM
admet-2088	1184	6	(	(	PUNCT
admet-2088	1184	7	2017	2017	NUM
admet-2088	1184	8	)	)	PUNCT
admet-2088	1184	9	53	53	NUM
admet-2088	1184	10	-	-	SYM
admet-2088	1184	11	69	69	NUM
admet-2088	1184	12	.	.	PUNCT
admet-2088	1185	1	https://doi.org/10.1039/c7cs00152e	https://doi.org/10.1039/c7cs00152e	X
admet-2088	1185	2	.	.	PUNCT
admet-2088	1186	1	[	[	X
admet-2088	1186	2	119	119	NUM
admet-2088	1186	3	]	]	X
admet-2088	1186	4	f.	f.	PROPN
admet-2088	1186	5	salehi	salehi	PROPN
admet-2088	1186	6	,	,	PUNCT
admet-2088	1186	7	f.	f.	PROPN
admet-2088	1186	8	daneshvar	daneshvar	PROPN
admet-2088	1186	9	,	,	PUNCT
admet-2088	1186	10	m.	m.	PROPN
admet-2088	1186	11	karimi	karimi	PROPN
admet-2088	1186	12	,	,	PUNCT
admet-2088	1186	13	r.d	r.d	PROPN
admet-2088	1186	14	.	.	PROPN
admet-2088	1186	15	vais	vais	PROPN
admet-2088	1186	16	,	,	PUNCT
admet-2088	1186	17	m.a	m.a	PROPN
admet-2088	1186	18	.	.	PROPN
admet-2088	1186	19	mosleh	mosleh	PROPN
admet-2088	1186	20	-	-	PUNCT
admet-2088	1186	21	shirazi	shirazi	PROPN
admet-2088	1186	22	,	,	PUNCT
admet-2088	1186	23	n.	n.	PROPN
admet-2088	1186	24	sattarahmady	sattarahmady	PROPN
admet-2088	1186	25	.	.	PUNCT
admet-2088	1187	1	enhanced	enhance	VERB
admet-2088	1187	2	melanoma	melanoma	NOUN
admet-2088	1187	3	cell	cell	NOUN
admet-2088	1187	4	-	-	PUNCT
admet-2088	1187	5	killing	killing	NOUN
admet-2088	1187	6	by	by	ADP
admet-2088	1187	7	combined	combined	ADJ
admet-2088	1187	8	phototherapy	phototherapy	NOUN
admet-2088	1187	9	/	/	SYM
admet-2088	1187	10	radiotherapy	radiotherapy	NOUN
admet-2088	1187	11	using	use	VERB
admet-2088	1187	12	a	a	DET
admet-2088	1187	13	mesoporous	mesoporous	ADJ
admet-2088	1187	14	platinum	platinum	NOUN
admet-2088	1187	15	nanostructure	nanostructure	NOUN
admet-2088	1187	16	.	.	PUNCT
admet-2088	1188	1	photodiagnosis	photodiagnosis	NOUN
admet-2088	1188	2	and	and	CCONJ
admet-2088	1188	3	photodynamic	photodynamic	ADJ
admet-2088	1188	4	therapy	therapy	NOUN
admet-2088	1188	5	28	28	NUM
admet-2088	1188	6	(	(	PUNCT
admet-2088	1188	7	2019	2019	NUM
admet-2088	1188	8	)	)	PUNCT
admet-2088	1188	9	300	300	NUM
admet-2088	1188	10	-	-	SYM
admet-2088	1188	11	307	307	NUM
admet-2088	1188	12	.	.	PUNCT
admet-2088	1189	1	https://doi.org/10.1016/j.pdpdt.2019.10.001	https://doi.org/10.1016/j.pdpdt.2019.10.001	NOUN
admet-2088	1189	2	.	.	PUNCT
admet-2088	1190	1	[	[	X
admet-2088	1190	2	120	120	NUM
admet-2088	1190	3	]	]	X
admet-2088	1190	4	i.i	i.i	PROPN
admet-2088	1190	5	.	.	PROPN
admet-2088	1190	6	slowing	slowing	NOUN
admet-2088	1190	7	,	,	PUNCT
admet-2088	1190	8	b.g	b.g	PROPN
admet-2088	1190	9	.	.	PROPN
admet-2088	1190	10	trewyn	trewyn	PROPN
admet-2088	1190	11	,	,	PUNCT
admet-2088	1190	12	s.	s.	PROPN
admet-2088	1190	13	giri	giri	PROPN
admet-2088	1190	14	,	,	PUNCT
admet-2088	1190	15	v.s.y	v.s.y	NOUN
admet-2088	1190	16	.	.	PUNCT
admet-2088	1191	1	lin	lin	PROPN
admet-2088	1191	2	.	.	PUNCT
admet-2088	1192	1	mesoporous	mesoporous	ADJ
admet-2088	1192	2	silica	silica	NOUN
admet-2088	1192	3	nanoparticles	nanoparticle	NOUN
admet-2088	1192	4	for	for	ADP
admet-2088	1192	5	drug	drug	NOUN
admet-2088	1192	6	delivery	delivery	NOUN
admet-2088	1192	7	and	and	CCONJ
admet-2088	1192	8	biosensing	biosensing	NOUN
admet-2088	1192	9	applications	application	NOUN
admet-2088	1192	10	.	.	PUNCT
admet-2088	1193	1	advanced	advanced	ADJ
admet-2088	1193	2	functional	functional	ADJ
admet-2088	1193	3	materials	material	NOUN
admet-2088	1193	4	17	17	NUM
admet-2088	1193	5	(	(	PUNCT
admet-2088	1193	6	2007	2007	NUM
admet-2088	1193	7	)	)	PUNCT
admet-2088	1193	8	1225	1225	NUM
admet-2088	1193	9	-	-	SYM
admet-2088	1193	10	1236	1236	NUM
admet-2088	1193	11	.	.	PUNCT
admet-2088	1194	1	https://doi.org/10.1002/adfm.200601191	https://doi.org/10.1002/adfm.200601191	NOUN
admet-2088	1194	2	.	.	PUNCT
admet-2088	1195	1	[	[	X
admet-2088	1195	2	121	121	NUM
admet-2088	1195	3	]	]	X
admet-2088	1195	4	n.p	n.p	PROPN
admet-2088	1195	5	.	.	PROPN
admet-2088	1195	6	truong	truong	PROPN
admet-2088	1195	7	,	,	PUNCT
admet-2088	1195	8	m.r	m.r	PROPN
admet-2088	1195	9	.	.	PROPN
admet-2088	1195	10	whittaker	whittaker	PROPN
admet-2088	1195	11	,	,	PUNCT
admet-2088	1195	12	c.w	c.w	PROPN
admet-2088	1195	13	.	.	PROPN
admet-2088	1195	14	mak	mak	PROPN
admet-2088	1195	15	,	,	PUNCT
admet-2088	1195	16	t.p	t.p	PROPN
admet-2088	1195	17	.	.	PROPN
admet-2088	1195	18	davis	davis	PROPN
admet-2088	1195	19	.	.	PUNCT
admet-2088	1196	1	the	the	DET
admet-2088	1196	2	importance	importance	NOUN
admet-2088	1196	3	of	of	ADP
admet-2088	1196	4	nanoparticle	nanoparticle	NOUN
admet-2088	1196	5	shape	shape	NOUN
admet-2088	1196	6	in	in	ADP
admet-2088	1196	7	cancer	cancer	NOUN
admet-2088	1196	8	drug	drug	NOUN
admet-2088	1196	9	delivery	delivery	NOUN
admet-2088	1196	10	.	.	PUNCT
admet-2088	1197	1	expert	expert	ADJ
admet-2088	1197	2	opinion	opinion	NOUN
admet-2088	1197	3	on	on	ADP
admet-2088	1197	4	drug	drug	NOUN
admet-2088	1197	5	delivery	delivery	NOUN
admet-2088	1197	6	12	12	NUM
admet-2088	1197	7	(	(	PUNCT
admet-2088	1197	8	2015	2015	NUM
admet-2088	1197	9	)	)	PUNCT
admet-2088	1197	10	129	129	NUM
admet-2088	1197	11	-	-	SYM
admet-2088	1197	12	142	142	NUM
admet-2088	1197	13	.	.	PUNCT
admet-2088	1198	1	https://doi.org/10.1517/17425247.2014.950564	https://doi.org/10.1517/17425247.2014.950564	PROPN
admet-2088	1198	2	.	.	PUNCT
admet-2088	1199	1	[	[	X
admet-2088	1199	2	122	122	NUM
admet-2088	1199	3	]	]	X
admet-2088	1199	4	m.	m.	NOUN
admet-2088	1199	5	jeyaraj	jeyaraj	PROPN
admet-2088	1199	6	,	,	PUNCT
admet-2088	1199	7	s.	s.	PROPN
admet-2088	1199	8	gurunathan	gurunathan	PROPN
admet-2088	1199	9	,	,	PUNCT
admet-2088	1199	10	m.	m.	NOUN
admet-2088	1199	11	qasim	qasim	PROPN
admet-2088	1199	12	,	,	PUNCT
admet-2088	1199	13	m.	m.	PROPN
admet-2088	1199	14	kang	kang	PROPN
admet-2088	1199	15	,	,	PUNCT
admet-2088	1199	16	j.	j.	PROPN
admet-2088	1199	17	kim	kim	PROPN
admet-2088	1199	18	.	.	PUNCT
admet-2088	1200	1	a	a	DET
admet-2088	1200	2	comprehensive	comprehensive	ADJ
admet-2088	1200	3	review	review	NOUN
admet-2088	1200	4	on	on	ADP
admet-2088	1200	5	the	the	DET
admet-2088	1200	6	synthesis	synthesis	NOUN
admet-2088	1200	7	,	,	PUNCT
admet-2088	1200	8	characterization	characterization	NOUN
admet-2088	1200	9	,	,	PUNCT
admet-2088	1200	10	and	and	CCONJ
admet-2088	1200	11	biomedical	biomedical	ADJ
admet-2088	1200	12	application	application	NOUN
admet-2088	1200	13	of	of	ADP
admet-2088	1200	14	platinum	platinum	NOUN
admet-2088	1200	15	nanoparticles	nanoparticle	NOUN
admet-2088	1200	16	.	.	PUNCT
admet-2088	1201	1	nanomaterials	nanomaterial	NOUN
admet-2088	1201	2	9	9	NUM
admet-2088	1201	3	(	(	PUNCT
admet-2088	1201	4	2019	2019	NUM
admet-2088	1201	5	)	)	PUNCT
admet-2088	1201	6	2019	2019	NUM
admet-2088	1201	7	.	.	PUNCT
admet-2088	1202	1	https://doi.org/10.3390/nano9121719	https://doi.org/10.3390/nano9121719	PROPN
admet-2088	1202	2	.	.	PUNCT
admet-2088	1203	1	[	[	X
admet-2088	1203	2	123	123	NUM
admet-2088	1203	3	]	]	PUNCT
admet-2088	1203	4	s.	s.	PROPN
admet-2088	1203	5	yang	yang	PROPN
admet-2088	1203	6	,	,	PUNCT
admet-2088	1203	7	l.	l.	PROPN
admet-2088	1203	8	chen	chen	PROPN
admet-2088	1203	9	,	,	PUNCT
admet-2088	1203	10	x.	x.	PROPN
admet-2088	1203	11	zhou	zhou	PROPN
admet-2088	1203	12	,	,	PUNCT
admet-2088	1203	13	p.	p.	PROPN
admet-2088	1203	14	sun	sun	PROPN
admet-2088	1203	15	,	,	PUNCT
admet-2088	1203	16	l.	l.	PROPN
admet-2088	1203	17	fu	fu	PROPN
admet-2088	1203	18	,	,	PUNCT
admet-2088	1203	19	y.	y.	PROPN
admet-2088	1203	20	you	you	PRON
admet-2088	1203	21	,	,	PUNCT
admet-2088	1203	22	m.	m.	PROPN
admet-2088	1203	23	xu	xu	PROPN
admet-2088	1203	24	,	,	PUNCT
admet-2088	1203	25	z.	z.	PROPN
admet-2088	1203	26	you	you	PRON
admet-2088	1203	27	,	,	PUNCT
admet-2088	1203	28	g.	g.	PROPN
admet-2088	1203	29	kai	kai	PROPN
admet-2088	1203	30	,	,	PUNCT
admet-2088	1203	31	c.	c.	PROPN
admet-2088	1203	32	he	he	PRON
admet-2088	1203	33	.	.	PUNCT
admet-2088	1204	1	tumor	tumor	NOUN
admet-2088	1204	2	-	-	PUNCT
admet-2088	1204	3	targeted	target	VERB
admet-2088	1204	4	biodegradable	biodegradable	ADJ
admet-2088	1204	5	multifunctional	multifunctional	ADJ
admet-2088	1204	6	nanoparticles	nanoparticle	NOUN
admet-2088	1204	7	for	for	ADP
admet-2088	1204	8	cancer	cancer	NOUN
admet-2088	1204	9	theranostics	theranostic	NOUN
admet-2088	1204	10	.	.	PUNCT
admet-2088	1205	1	chemical	chemical	PROPN
admet-2088	1205	2	engineering	engineering	PROPN
admet-2088	1205	3	journal	journal	PROPN
admet-2088	1205	4	378	378	NUM
admet-2088	1205	5	(	(	PUNCT
admet-2088	1205	6	2019	2019	NUM
admet-2088	1205	7	)	)	PUNCT
admet-2088	1205	8	122171	122171	NUM
admet-2088	1205	9	.	.	PUNCT
admet-2088	1206	1	https://doi.org/10.1016/j.cej.2019.122171	https://doi.org/10.1016/j.cej.2019.122171	PROPN
admet-2088	1206	2	.	.	PUNCT
admet-2088	1207	1	[	[	X
admet-2088	1207	2	124	124	NUM
admet-2088	1207	3	]	]	PUNCT
admet-2088	1207	4	m.	m.	NOUN
admet-2088	1207	5	pourmadadi	pourmadadi	NOUN
admet-2088	1207	6	,	,	PUNCT
admet-2088	1207	7	p.	p.	PROPN
admet-2088	1207	8	abbasi	abbasi	PROPN
admet-2088	1207	9	,	,	PUNCT
admet-2088	1207	10	md.m	md.m	PROPN
admet-2088	1207	11	.	.	PUNCT
admet-2088	1207	12	eshaghi	eshaghi	PROPN
admet-2088	1207	13	,	,	PUNCT
admet-2088	1207	14	a.	a.	NOUN
admet-2088	1207	15	bakhshi	bakhshi	PROPN
admet-2088	1207	16	,	,	PUNCT
admet-2088	1207	17	a.-l.e	a.-l.e	PROPN
admet-2088	1207	18	.	.	PUNCT
admet-2088	1208	1	manicum	manicum	NOUN
admet-2088	1208	2	,	,	PUNCT
admet-2088	1208	3	a.	a.	PROPN
admet-2088	1208	4	rahdar	rahdar	PROPN
admet-2088	1208	5	,	,	PUNCT
admet-2088	1208	6	s.	s.	PROPN
admet-2088	1208	7	pandey	pandey	PROPN
admet-2088	1208	8	,	,	PUNCT
admet-2088	1208	9	s.	s.	PROPN
admet-2088	1208	10	jadoun	jadoun	PROPN
admet-2088	1208	11	,	,	PUNCT
admet-2088	1208	12	a.m.	a.m.	PROPN
admet-2088	1208	13	díez	díez	PROPN
admet-2088	1208	14	-	-	PUNCT
admet-2088	1208	15	pascual	pascual	ADJ
admet-2088	1208	16	.	.	PUNCT
admet-2088	1209	1	curcumin	curcumin	NOUN
admet-2088	1209	2	delivery	delivery	NOUN
admet-2088	1209	3	and	and	CCONJ
admet-2088	1209	4	co	co	NOUN
admet-2088	1209	5	-	-	NOUN
admet-2088	1209	6	delivery	delivery	NOUN
admet-2088	1209	7	based	base	VERB
admet-2088	1209	8	on	on	ADP
admet-2088	1209	9	nanomaterials	nanomaterial	NOUN
admet-2088	1209	10	as	as	ADP
admet-2088	1209	11	an	an	DET
admet-2088	1209	12	effective	effective	ADJ
admet-2088	1209	13	approach	approach	NOUN
admet-2088	1209	14	for	for	ADP
admet-2088	1209	15	cancer	cancer	NOUN
admet-2088	1209	16	therapy	therapy	NOUN
admet-2088	1209	17	.	.	PUNCT
admet-2088	1210	1	journal	journal	PROPN
admet-2088	1210	2	of	of	ADP
admet-2088	1210	3	drug	drug	NOUN
admet-2088	1210	4	delivery	delivery	NOUN
admet-2088	1210	5	science	science	NOUN
admet-2088	1210	6	and	and	CCONJ
admet-2088	1210	7	technology	technology	NOUN
admet-2088	1210	8	78	78	NUM
admet-2088	1210	9	(	(	PUNCT
admet-2088	1210	10	2022	2022	NUM
admet-2088	1210	11	)	)	PUNCT
admet-2088	1210	12	103982	103982	NUM
admet-2088	1210	13	.	.	PUNCT
admet-2088	1211	1	https://doi.org/10.1016/j.jddst.2022.103982	https://doi.org/10.1016/j.jddst.2022.103982	NOUN
admet-2088	1211	2	.	.	PUNCT
admet-2088	1212	1	[	[	X
admet-2088	1212	2	125	125	NUM
admet-2088	1212	3	]	]	PUNCT
admet-2088	1212	4	m.	m.	NOUN
admet-2088	1212	5	ghazaeian	ghazaeian	PROPN
admet-2088	1212	6	,	,	PUNCT
admet-2088	1212	7	k.	k.	PROPN
admet-2088	1212	8	khorsandi	khorsandi	PROPN
admet-2088	1212	9	,	,	PUNCT
admet-2088	1212	10	r.	r.	PROPN
admet-2088	1212	11	hosseinzadeh	hosseinzadeh	PROPN
admet-2088	1212	12	,	,	PUNCT
admet-2088	1212	13	a.	a.	NOUN
admet-2088	1212	14	naderi	naderi	PROPN
admet-2088	1212	15	,	,	PUNCT
admet-2088	1212	16	h.	h.	PROPN
admet-2088	1212	17	abrahamse	abrahamse	PROPN
admet-2088	1212	18	.	.	PUNCT
admet-2088	1213	1	curcumin	curcumin	NOUN
admet-2088	1213	2	–	–	PUNCT
admet-2088	1213	3	silica	silica	NOUN
admet-2088	1213	4	nanocomplex	nanocomplex	NOUN
admet-2088	1213	5	preparation	preparation	NOUN
admet-2088	1213	6	,	,	PUNCT
admet-2088	1213	7	hemoglobin	hemoglobin	NOUN
admet-2088	1213	8	and	and	CCONJ
admet-2088	1213	9	dna	dna	NOUN
admet-2088	1213	10	interaction	interaction	NOUN
admet-2088	1213	11	and	and	CCONJ
admet-2088	1213	12	photocytotoxicity	photocytotoxicity	NOUN
admet-2088	1213	13	against	against	ADP
admet-2088	1213	14	melanoma	melanoma	NOUN
admet-2088	1213	15	cancer	cancer	NOUN
admet-2088	1213	16	cells	cell	NOUN
admet-2088	1213	17	.	.	PUNCT
admet-2088	1214	1	journal	journal	NOUN
admet-2088	1214	2	of	of	ADP
admet-2088	1214	3	biomolecular	biomolecular	ADJ
admet-2088	1214	4	structure	structure	NOUN
admet-2088	1214	5	and	and	CCONJ
admet-2088	1214	6	dynamics	dynamic	NOUN
admet-2088	1214	7	39	39	NUM
admet-2088	1214	8	(	(	PUNCT
admet-2088	1214	9	2021	2021	NUM
admet-2088	1214	10	)	)	PUNCT
admet-2088	1214	11	6606	6606	NUM
admet-2088	1214	12	-	-	SYM
admet-2088	1214	13	6616	6616	NUM
admet-2088	1214	14	.	.	PUNCT
admet-2088	1215	1	https://doi.org/10.1080/07391102.2020.1802342	https://doi.org/10.1080/07391102.2020.1802342	X
admet-2088	1215	2	.	.	PUNCT
admet-2088	1216	1	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	PROPN
admet-2088	1216	2	https://doi.org/10.1016/j.mtchem.2022.101308	https://doi.org/10.1016/j.mtchem.2022.101308	PROPN
admet-2088	1216	3	https://doi.org/10.1016/j.addr.2017.03.004	https://doi.org/10.1016/j.addr.2017.03.004	PROPN
admet-2088	1216	4	https://doi.org/10.1002/anie.201909880	https://doi.org/10.1002/anie.201909880	ADJ
admet-2088	1216	5	https://doi.org/10.1016/j.msec.2019.110375	https://doi.org/10.1016/j.msec.2019.110375	PROPN
admet-2088	1216	6	https://doi.org/10.1039/c5ra02921j	https://doi.org/10.1039/c5ra02921j	PROPN
admet-2088	1216	7	https://doi.org/10.1039/c5cc08418k	https://doi.org/10.1039/c5cc08418k	PROPN
admet-2088	1216	8	https://doi.org/10.1016/j.ejphar.2014.07.025	https://doi.org/10.1016/j.ejphar.2014.07.025	PROPN
admet-2088	1216	9	https://pubmed.ncbi.nlm.nih.gov/24403503/	https://pubmed.ncbi.nlm.nih.gov/24403503/	PROPN
admet-2088	1216	10	https://doi.org/10.1039/c7cs00152e	https://doi.org/10.1039/c7cs00152e	PROPN
admet-2088	1216	11	https://doi.org/10.1016/j.pdpdt.2019.10.001	https://doi.org/10.1016/j.pdpdt.2019.10.001	PROPN
admet-2088	1216	12	https://doi.org/10.1002/adfm.200601191	https://doi.org/10.1002/adfm.200601191	NOUN
admet-2088	1216	13	https://doi.org/10.1517/17425247.2014.950564	https://doi.org/10.1517/17425247.2014.950564	PROPN
admet-2088	1217	1	https://doi.org/10.3390/nano9121719	https://doi.org/10.3390/nano9121719	PROPN
admet-2088	1217	2	https://doi.org/10.1016/j.cej.2019.122171	https://doi.org/10.1016/j.cej.2019.122171	PROPN
admet-2088	1218	1	https://doi.org/10.1016/j.jddst.2022.103982	https://doi.org/10.1016/j.jddst.2022.103982	PROPN
admet-2088	1218	2	https://doi.org/10.1080/07391102.2020.1802342	https://doi.org/10.1080/07391102.2020.1802342	PROPN
admet-2088	1218	3	m.	m.	NOUN
admet-2088	1218	4	kulkarni	kulkarni	PROPN
admet-2088	1218	5	et	et	PROPN
admet-2088	1218	6	al	al	PROPN
admet-2088	1218	7	.	.	PROPN
admet-2088	1218	8	admet	admet	PROPN
admet-2088	1218	9	&	&	CCONJ
admet-2088	1218	10	dmpk	dmpk	PROPN
admet-2088	1218	11	12(1	12(1	PROPN
admet-2088	1218	12	)	)	PUNCT
admet-2088	1218	13	(	(	PUNCT
admet-2088	1218	14	2024	2024	NUM
admet-2088	1218	15	)	)	PUNCT
admet-2088	1218	16	107	107	NUM
admet-2088	1218	17	-	-	SYM
admet-2088	1218	18	150	150	NUM
admet-2088	1218	19	144	144	NUM
admet-2088	1218	20	[	[	X
admet-2088	1218	21	126	126	NUM
admet-2088	1218	22	]	]	X
admet-2088	1218	23	n.m	n.m	PROPN
admet-2088	1218	24	.	.	PROPN
admet-2088	1218	25	idris	idris	PROPN
admet-2088	1218	26	,	,	PUNCT
admet-2088	1218	27	m.k	m.k	PROPN
admet-2088	1218	28	.	.	PROPN
admet-2088	1218	29	gnanasammandhan	gnanasammandhan	PROPN
admet-2088	1218	30	,	,	PUNCT
admet-2088	1218	31	j.	j.	PROPN
admet-2088	1218	32	zhang	zhang	PROPN
admet-2088	1218	33	,	,	PUNCT
admet-2088	1218	34	p.c	p.c	PROPN
admet-2088	1218	35	.	.	PROPN
admet-2088	1218	36	ho	ho	PROPN
admet-2088	1218	37	,	,	PUNCT
admet-2088	1218	38	r.	r.	PROPN
admet-2088	1218	39	mahendran	mahendran	PROPN
admet-2088	1218	40	,	,	PUNCT
admet-2088	1218	41	y.	y.	PROPN
admet-2088	1218	42	zhang	zhang	PROPN
admet-2088	1218	43	.	.	PUNCT
admet-2088	1219	1	in	in	ADP
admet-2088	1219	2	vivo	vivo	ADJ
admet-2088	1219	3	photodynamic	photodynamic	ADJ
admet-2088	1219	4	therapy	therapy	NOUN
admet-2088	1219	5	using	use	VERB
admet-2088	1219	6	upconversion	upconversion	NOUN
admet-2088	1219	7	nanoparticles	nanoparticle	NOUN
admet-2088	1219	8	as	as	ADP
admet-2088	1219	9	remote	remote	ADV
admet-2088	1219	10	-	-	PUNCT
admet-2088	1219	11	controlled	control	VERB
admet-2088	1219	12	nanotransducers	nanotransducer	NOUN
admet-2088	1219	13	.	.	PUNCT
admet-2088	1220	1	nature	nature	NOUN
admet-2088	1220	2	medicine	medicine	NOUN
admet-2088	1220	3	18	18	NUM
admet-2088	1220	4	(	(	PUNCT
admet-2088	1220	5	2012	2012	NUM
admet-2088	1220	6	)	)	PUNCT
admet-2088	1220	7	1580	1580	NUM
admet-2088	1220	8	-	-	SYM
admet-2088	1220	9	1585	1585	NUM
admet-2088	1220	10	.	.	PUNCT
admet-2088	1221	1	https://doi.org/10.1038/nm.2933	https://doi.org/10.1038/nm.2933	NOUN
admet-2088	1221	2	.	.	PUNCT
admet-2088	1222	1	[	[	X
admet-2088	1222	2	127	127	NUM
admet-2088	1222	3	]	]	X
admet-2088	1222	4	s.e	s.e	PROPN
admet-2088	1222	5	.	.	PROPN
admet-2088	1222	6	kim	kim	PROPN
admet-2088	1222	7	,	,	PUNCT
admet-2088	1222	8	l.	l.	PROPN
admet-2088	1222	9	zhang	zhang	PROPN
admet-2088	1222	10	,	,	PUNCT
admet-2088	1222	11	k.	k.	PROPN
admet-2088	1222	12	ma	ma	PROPN
admet-2088	1222	13	,	,	PUNCT
admet-2088	1222	14	m.	m.	PROPN
admet-2088	1222	15	riegman	riegman	PROPN
admet-2088	1222	16	,	,	PUNCT
admet-2088	1222	17	f.	f.	PROPN
admet-2088	1222	18	chen	chen	PROPN
admet-2088	1222	19	,	,	PUNCT
admet-2088	1222	20	i.	i.	PROPN
admet-2088	1222	21	ingold	ingold	PROPN
admet-2088	1222	22	,	,	PUNCT
admet-2088	1222	23	m.	m.	NOUN
admet-2088	1222	24	conrad	conrad	PROPN
admet-2088	1222	25	,	,	PUNCT
admet-2088	1222	26	m.z	m.z	PROPN
admet-2088	1222	27	.	.	PROPN
admet-2088	1222	28	turker	turker	PROPN
admet-2088	1222	29	,	,	PUNCT
admet-2088	1222	30	m.	m.	NOUN
admet-2088	1222	31	gao	gao	PROPN
admet-2088	1222	32	,	,	PUNCT
admet-2088	1222	33	x.	x.	PROPN
admet-2088	1222	34	jiang	jiang	PROPN
admet-2088	1222	35	,	,	PUNCT
admet-2088	1222	36	s.	s.	PROPN
admet-2088	1222	37	monette	monette	PROPN
admet-2088	1222	38	,	,	PUNCT
admet-2088	1222	39	m.	m.	NOUN
admet-2088	1222	40	pauliah	pauliah	PROPN
admet-2088	1222	41	,	,	PUNCT
admet-2088	1222	42	m.	m.	NOUN
admet-2088	1222	43	gonen	gonen	PROPN
admet-2088	1222	44	,	,	PUNCT
admet-2088	1222	45	p.	p.	NOUN
admet-2088	1222	46	zanzonico	zanzonico	NOUN
admet-2088	1222	47	,	,	PUNCT
admet-2088	1222	48	t.	t.	PROPN
admet-2088	1222	49	quinn	quinn	PROPN
admet-2088	1222	50	,	,	PUNCT
admet-2088	1222	51	u.	u.	PROPN
admet-2088	1222	52	wiesner	wiesner	PROPN
admet-2088	1222	53	,	,	PUNCT
admet-2088	1222	54	m.s	m.s	PROPN
admet-2088	1222	55	.	.	PROPN
admet-2088	1222	56	bradbury	bradbury	PROPN
admet-2088	1222	57	,	,	PUNCT
admet-2088	1222	58	m.	m.	NOUN
admet-2088	1222	59	overholtzer	overholtzer	NOUN
admet-2088	1222	60	.	.	PUNCT
admet-2088	1223	1	ultrasmall	ultrasmall	ADJ
admet-2088	1223	2	nanoparticles	nanoparticle	NOUN
admet-2088	1223	3	induce	induce	VERB
admet-2088	1223	4	ferroptosis	ferroptosis	NOUN
admet-2088	1223	5	in	in	ADP
admet-2088	1223	6	nutrient	nutrient	NOUN
admet-2088	1223	7	-	-	PUNCT
admet-2088	1223	8	deprived	deprive	VERB
admet-2088	1223	9	cancer	cancer	NOUN
admet-2088	1223	10	cells	cell	NOUN
admet-2088	1223	11	and	and	CCONJ
admet-2088	1223	12	suppress	suppress	VERB
admet-2088	1223	13	tumour	tumour	NOUN
admet-2088	1223	14	growth	growth	NOUN
admet-2088	1223	15	.	.	PUNCT
admet-2088	1224	1	nature	nature	NOUN
admet-2088	1224	2	nanotechnology	nanotechnology	PROPN
admet-2088	1224	3	11	11	NUM
admet-2088	1224	4	(	(	PUNCT
admet-2088	1224	5	2016	2016	NUM
admet-2088	1224	6	)	)	PUNCT
admet-2088	1224	7	977	977	NUM
admet-2088	1224	8	-	-	SYM
admet-2088	1224	9	985	985	NUM
admet-2088	1224	10	.	.	PUNCT
admet-2088	1225	1	https://doi.org/0.1038/nnano.2016.164	https://doi.org/0.1038/nnano.2016.164	NOUN
admet-2088	1225	2	.	.	PUNCT
admet-2088	1226	1	[	[	X
admet-2088	1226	2	128	128	NUM
admet-2088	1226	3	]	]	X
admet-2088	1226	4	h.	h.	PROPN
admet-2088	1226	5	wang	wang	PROPN
admet-2088	1226	6	,	,	PUNCT
admet-2088	1226	7	r.	r.	PROPN
admet-2088	1226	8	zhao	zhao	PROPN
admet-2088	1226	9	,	,	PUNCT
admet-2088	1226	10	y.	y.	PROPN
admet-2088	1226	11	li	li	PROPN
admet-2088	1226	12	,	,	PUNCT
admet-2088	1226	13	h.	h.	PROPN
admet-2088	1226	14	liu	liu	PROPN
admet-2088	1226	15	,	,	PUNCT
admet-2088	1226	16	f.	f.	PROPN
admet-2088	1226	17	li	li	PROPN
admet-2088	1226	18	,	,	PUNCT
admet-2088	1226	19	y.	y.	PROPN
admet-2088	1226	20	zhao	zhao	PROPN
admet-2088	1226	21	,	,	PUNCT
admet-2088	1227	1	g.	g.	PROPN
admet-2088	1227	2	nie	nie	PROPN
admet-2088	1227	3	.	.	PROPN
admet-2088	1227	4	aspect	aspect	PROPN
admet-2088	1227	5	ratios	ratio	NOUN
admet-2088	1227	6	of	of	ADP
admet-2088	1227	7	gold	gold	NOUN
admet-2088	1227	8	nanoshell	nanoshell	NOUN
admet-2088	1227	9	capsules	capsule	NOUN
admet-2088	1227	10	mediated	mediate	VERB
admet-2088	1227	11	melanoma	melanoma	NOUN
admet-2088	1227	12	ablation	ablation	NOUN
admet-2088	1227	13	by	by	ADP
admet-2088	1227	14	synergistic	synergistic	ADJ
admet-2088	1227	15	photothermal	photothermal	ADJ
admet-2088	1227	16	therapy	therapy	NOUN
admet-2088	1227	17	and	and	CCONJ
admet-2088	1227	18	chemotherapy	chemotherapy	NOUN
admet-2088	1227	19	.	.	PUNCT
admet-2088	1228	1	nanomedicine	nanomedicine	PROPN
admet-2088	1228	2	:	:	PUNCT
admet-2088	1228	3	nanotechnology	nanotechnology	NOUN
admet-2088	1228	4	,	,	PUNCT
admet-2088	1228	5	biology	biology	NOUN
admet-2088	1228	6	and	and	CCONJ
admet-2088	1228	7	medicine	medicine	NOUN
admet-2088	1228	8	12	12	NUM
admet-2088	1228	9	(	(	PUNCT
admet-2088	1228	10	2016	2016	NUM
admet-2088	1228	11	)	)	PUNCT
admet-2088	1228	12	439	439	NUM
admet-2088	1228	13	-	-	SYM
admet-2088	1228	14	448	448	NUM
admet-2088	1228	15	.	.	PUNCT
admet-2088	1229	1	https://doi.org/10.1016/j.nano.2015.11.013	https://doi.org/10.1016/j.nano.2015.11.013	X
admet-2088	1229	2	.	.	PUNCT
admet-2088	1230	1	[	[	X
admet-2088	1230	2	129	129	NUM
admet-2088	1230	3	]	]	PUNCT
admet-2088	1230	4	z.	z.	PROPN
admet-2088	1230	5	zhang	zhang	PROPN
admet-2088	1230	6	,	,	PUNCT
admet-2088	1230	7	x.	x.	PROPN
admet-2088	1230	8	zhang	zhang	PROPN
admet-2088	1230	9	,	,	PUNCT
admet-2088	1230	10	s.	s.	PROPN
admet-2088	1230	11	zhao	zhao	PROPN
admet-2088	1230	12	,	,	PUNCT
admet-2088	1230	13	w.	w.	PROPN
admet-2088	1230	14	feng	feng	PROPN
admet-2088	1230	15	,	,	PUNCT
admet-2088	1230	16	h.	h.	PROPN
admet-2088	1230	17	huang	huang	PROPN
admet-2088	1230	18	,	,	PUNCT
admet-2088	1230	19	l.	l.	PROPN
admet-2088	1230	20	ding	ding	PROPN
admet-2088	1230	21	,	,	PUNCT
admet-2088	1230	22	y.	y.	PROPN
admet-2088	1230	23	chen	chen	PROPN
admet-2088	1230	24	,	,	PUNCT
admet-2088	1230	25	b.	b.	PROPN
admet-2088	1230	26	chen	chen	PROPN
admet-2088	1230	27	.	.	PUNCT
admet-2088	1231	1	engineering	engineering	NOUN
admet-2088	1231	2	2d	2d	NUM
admet-2088	1231	3	silicenebased	silicenebase	VERB
admet-2088	1231	4	core	core	NOUN
admet-2088	1231	5	/	/	SYM
admet-2088	1231	6	shell	shell	NOUN
admet-2088	1231	7	nanomedicine	nanomedicine	NOUN
admet-2088	1231	8	for	for	ADP
admet-2088	1231	9	gsdme	gsdme	NOUN
admet-2088	1231	10	-	-	PUNCT
admet-2088	1231	11	induced	induce	VERB
admet-2088	1231	12	synergistic	synergistic	ADJ
admet-2088	1231	13	pyroptosis	pyroptosis	NOUN
admet-2088	1231	14	and	and	CCONJ
admet-2088	1231	15	photonic	photonic	ADJ
admet-2088	1231	16	hyperthermia	hyperthermia	NOUN
admet-2088	1231	17	of	of	ADP
admet-2088	1231	18	melanoma	melanoma	NOUN
admet-2088	1231	19	carcinoma	carcinoma	NOUN
admet-2088	1231	20	.	.	PUNCT
admet-2088	1232	1	chemical	chemical	PROPN
admet-2088	1232	2	engineering	engineering	PROPN
admet-2088	1232	3	journal	journal	PROPN
admet-2088	1232	4	454	454	NUM
admet-2088	1232	5	(	(	PUNCT
admet-2088	1232	6	2023	2023	NUM
admet-2088	1232	7	)	)	PUNCT
admet-2088	1232	8	140175	140175	NUM
admet-2088	1232	9	.	.	PUNCT
admet-2088	1233	1	https://doi.org/10.1016/j.cej.2022.140175	https://doi.org/10.1016/j.cej.2022.140175	PROPN
admet-2088	1233	2	.	.	PUNCT
admet-2088	1234	1	[	[	X
admet-2088	1234	2	130	130	NUM
admet-2088	1234	3	]	]	PUNCT
admet-2088	1234	4	s.	s.	PROPN
admet-2088	1234	5	sapino	sapino	PROPN
admet-2088	1234	6	,	,	PUNCT
admet-2088	1234	7	e.	e.	PROPN
admet-2088	1234	8	ugazio	ugazio	PROPN
admet-2088	1234	9	,	,	PUNCT
admet-2088	1234	10	l.	l.	PROPN
admet-2088	1234	11	gastaldi	gastaldi	PROPN
admet-2088	1234	12	,	,	PUNCT
admet-2088	1234	13	i.	i.	PROPN
admet-2088	1234	14	miletto	miletto	PROPN
admet-2088	1234	15	,	,	PUNCT
admet-2088	1234	16	g.	g.	PROPN
admet-2088	1234	17	berlier	berlier	PROPN
admet-2088	1234	18	,	,	PUNCT
admet-2088	1234	19	d.	d.	PROPN
admet-2088	1234	20	zonari	zonari	PROPN
admet-2088	1234	21	,	,	PUNCT
admet-2088	1234	22	s.	s.	PROPN
admet-2088	1234	23	oliaro	oliaro	NOUN
admet-2088	1234	24	-	-	PUNCT
admet-2088	1234	25	bosso	bosso	NOUN
admet-2088	1234	26	.	.	PUNCT
admet-2088	1235	1	mesoporous	mesoporous	ADJ
admet-2088	1235	2	silica	silica	NOUN
admet-2088	1235	3	as	as	ADP
admet-2088	1235	4	topical	topical	ADJ
admet-2088	1235	5	nanocarriers	nanocarrier	NOUN
admet-2088	1235	6	for	for	ADP
admet-2088	1235	7	quercetin	quercetin	NOUN
admet-2088	1235	8	:	:	PUNCT
admet-2088	1235	9	characterization	characterization	NOUN
admet-2088	1235	10	and	and	CCONJ
admet-2088	1235	11	in	in	ADP
admet-2088	1235	12	vitro	vitro	X
admet-2088	1235	13	studies	study	NOUN
admet-2088	1235	14	.	.	PUNCT
admet-2088	1236	1	european	european	PROPN
admet-2088	1236	2	journal	journal	PROPN
admet-2088	1236	3	of	of	ADP
admet-2088	1236	4	pharmaceutics	pharmaceutic	NOUN
admet-2088	1236	5	and	and	CCONJ
admet-2088	1236	6	biopharmaceutics	biopharmaceutic	NOUN
admet-2088	1236	7	89	89	NUM
admet-2088	1236	8	(	(	PUNCT
admet-2088	1236	9	2015	2015	NUM
admet-2088	1236	10	)	)	PUNCT
admet-2088	1236	11	116	116	NUM
admet-2088	1236	12	-	-	SYM
admet-2088	1236	13	125	125	NUM
admet-2088	1236	14	.	.	PUNCT
admet-2088	1237	1	https://doi.org/10.1016/j.ejpb.2014.11.022	https://doi.org/10.1016/j.ejpb.2014.11.022	NOUN
admet-2088	1237	2	.	.	PUNCT
admet-2088	1238	1	[	[	X
admet-2088	1238	2	131	131	NUM
admet-2088	1238	3	]	]	X
admet-2088	1238	4	r.j	r.j	PROPN
admet-2088	1238	5	.	.	PROPN
admet-2088	1238	6	gurr	gurr	PROPN
admet-2088	1238	7	.	.	PUNCT
admet-2088	1238	8	ultrafine	ultrafine	PROPN
admet-2088	1238	9	titanium	titanium	NOUN
admet-2088	1238	10	dioxide	dioxide	NOUN
admet-2088	1238	11	particles	particle	NOUN
admet-2088	1238	12	in	in	ADP
admet-2088	1238	13	the	the	DET
admet-2088	1238	14	absence	absence	NOUN
admet-2088	1238	15	of	of	ADP
admet-2088	1238	16	photoactivation	photoactivation	NOUN
admet-2088	1238	17	can	can	AUX
admet-2088	1238	18	induce	induce	VERB
admet-2088	1238	19	oxidative	oxidative	ADJ
admet-2088	1238	20	damage	damage	NOUN
admet-2088	1238	21	to	to	ADP
admet-2088	1238	22	human	human	ADJ
admet-2088	1238	23	bronchial	bronchial	ADJ
admet-2088	1238	24	epithelial	epithelial	ADJ
admet-2088	1238	25	cells	cell	NOUN
admet-2088	1238	26	.	.	PUNCT
admet-2088	1239	1	toxicology	toxicology	NOUN
admet-2088	1239	2	213	213	NUM
admet-2088	1239	3	(	(	PUNCT
admet-2088	1239	4	2005	2005	NUM
admet-2088	1239	5	)	)	PUNCT
admet-2088	1239	6	66	66	NUM
admet-2088	1239	7	-	-	SYM
admet-2088	1239	8	73	73	NUM
admet-2088	1239	9	.	.	PUNCT
admet-2088	1240	1	https://doi.org/10.1016/j.tox.2005.05.007	https://doi.org/10.1016/j.tox.2005.05.007	PROPN
admet-2088	1240	2	.	.	PUNCT
admet-2088	1241	1	[	[	X
admet-2088	1241	2	132	132	NUM
admet-2088	1241	3	]	]	PUNCT
admet-2088	1241	4	s.	s.	PROPN
admet-2088	1241	5	jafari	jafari	PROPN
admet-2088	1241	6	,	,	PUNCT
admet-2088	1241	7	b.	b.	PROPN
admet-2088	1241	8	mahyad	mahyad	PROPN
admet-2088	1241	9	,	,	PUNCT
admet-2088	1241	10	h.	h.	PROPN
admet-2088	1241	11	hashemzadeh	hashemzadeh	PROPN
admet-2088	1241	12	,	,	PUNCT
admet-2088	1241	13	s.	s.	PROPN
admet-2088	1241	14	janfaza	janfaza	PROPN
admet-2088	1241	15	,	,	PUNCT
admet-2088	1241	16	t.	t.	PROPN
admet-2088	1241	17	gholikhani	gholikhani	PROPN
admet-2088	1241	18	,	,	PUNCT
admet-2088	1241	19	l.	l.	PROPN
admet-2088	1241	20	tayebi	tayebi	PROPN
admet-2088	1241	21	.	.	PUNCT
admet-2088	1242	1	biomedical	biomedical	ADJ
admet-2088	1242	2	applications	application	NOUN
admet-2088	1242	3	of	of	ADP
admet-2088	1242	4	tio2	tio2	NOUN
admet-2088	1242	5	nanostructures	nanostructure	NOUN
admet-2088	1242	6	:	:	PUNCT
admet-2088	1242	7	recent	recent	ADJ
admet-2088	1242	8	advances	advance	NOUN
admet-2088	1242	9	.	.	PUNCT
admet-2088	1243	1	international	international	ADJ
admet-2088	1243	2	journal	journal	PROPN
admet-2088	1243	3	of	of	ADP
admet-2088	1243	4	nanomedicine	nanomedicine	NOUN
admet-2088	1243	5	15	15	NUM
admet-2088	1243	6	(	(	PUNCT
admet-2088	1243	7	2020	2020	NUM
admet-2088	1243	8	)	)	PUNCT
admet-2088	1243	9	34473470	34473470	NUM
admet-2088	1243	10	.	.	PUNCT
admet-2088	1244	1	https://doi.org/10.2147/ijn.s249441	https://doi.org/10.2147/ijn.s249441	NOUN
admet-2088	1244	2	.	.	PUNCT
admet-2088	1245	1	[	[	X
admet-2088	1245	2	133	133	NUM
admet-2088	1245	3	]	]	PUNCT
admet-2088	1245	4	a.	a.	NOUN
admet-2088	1245	5	meng	meng	PROPN
admet-2088	1245	6	,	,	PUNCT
admet-2088	1245	7	l.	l.	PROPN
admet-2088	1245	8	zhang	zhang	PROPN
admet-2088	1245	9	,	,	PUNCT
admet-2088	1245	10	b.	b.	PROPN
admet-2088	1245	11	cheng	cheng	PROPN
admet-2088	1245	12	,	,	PUNCT
admet-2088	1245	13	j.	j.	PROPN
admet-2088	1245	14	yu	yu	PROPN
admet-2088	1245	15	.	.	PUNCT
admet-2088	1246	1	dual	dual	ADJ
admet-2088	1246	2	cocatalysts	cocatalyst	NOUN
admet-2088	1246	3	in	in	ADP
admet-2088	1246	4	tio2	tio2	NOUN
admet-2088	1246	5	photocatalysis	photocatalysis	NOUN
admet-2088	1246	6	.	.	PUNCT
admet-2088	1247	1	advanced	advanced	ADJ
admet-2088	1247	2	materials	material	NOUN
admet-2088	1247	3	31	31	NUM
admet-2088	1247	4	(	(	PUNCT
admet-2088	1247	5	2019	2019	NUM
admet-2088	1247	6	)	)	PUNCT
admet-2088	1247	7	1807660	1807660	NUM
admet-2088	1247	8	.	.	PUNCT
admet-2088	1248	1	https://doi.org/10.1002/adma.201807660	https://doi.org/10.1002/adma.201807660	NOUN
admet-2088	1248	2	.	.	PUNCT
admet-2088	1249	1	[	[	X
admet-2088	1249	2	134	134	NUM
admet-2088	1249	3	]	]	X
admet-2088	1249	4	c.	c.	NOUN
admet-2088	1249	5	zarzzeka	zarzzeka	PROPN
admet-2088	1249	6	,	,	PUNCT
admet-2088	1249	7	j.	j.	PROPN
admet-2088	1249	8	goldoni	goldoni	PROPN
admet-2088	1249	9	,	,	PUNCT
admet-2088	1249	10	f.	f.	PROPN
admet-2088	1249	11	marafon	marafon	PROPN
admet-2088	1249	12	,	,	PUNCT
admet-2088	1249	13	w.g	w.g	PROPN
admet-2088	1249	14	.	.	PROPN
admet-2088	1249	15	sganzerla	sganzerla	PROPN
admet-2088	1249	16	,	,	PUNCT
admet-2088	1249	17	t.	t.	PROPN
admet-2088	1249	18	forster	forster	PROPN
admet-2088	1249	19	-	-	PUNCT
admet-2088	1249	20	carneiro	carneiro	PROPN
admet-2088	1249	21	,	,	PUNCT
admet-2088	1249	22	m.d	m.d	PROPN
admet-2088	1249	23	.	.	PROPN
admet-2088	1249	24	bagatini	bagatini	PROPN
admet-2088	1249	25	,	,	PUNCT
admet-2088	1249	26	l.	l.	PROPN
admet-2088	1249	27	maria	maria	PROPN
admet-2088	1249	28	,	,	PUNCT
admet-2088	1249	29	s.	s.	PROPN
admet-2088	1249	30	colpini	colpini	PROPN
admet-2088	1249	31	.	.	PUNCT
admet-2088	1250	1	use	use	NOUN
admet-2088	1250	2	of	of	ADP
admet-2088	1250	3	titanium	titanium	NOUN
admet-2088	1250	4	dioxide	dioxide	NOUN
admet-2088	1250	5	nanoparticles	nanoparticle	NOUN
admet-2088	1250	6	for	for	ADP
admet-2088	1250	7	cancer	cancer	NOUN
admet-2088	1250	8	treatment	treatment	NOUN
admet-2088	1250	9	:	:	PUNCT
admet-2088	1250	10	a	a	DET
admet-2088	1250	11	comprehensive	comprehensive	ADJ
admet-2088	1250	12	review	review	NOUN
admet-2088	1250	13	and	and	CCONJ
admet-2088	1250	14	bibliometric	bibliometric	ADJ
admet-2088	1250	15	analysis	analysis	NOUN
admet-2088	1250	16	.	.	PUNCT
admet-2088	1251	1	biocatalysis	biocatalysis	NOUN
admet-2088	1251	2	and	and	CCONJ
admet-2088	1251	3	agricultural	agricultural	ADJ
admet-2088	1251	4	biotechnology	biotechnology	NOUN
admet-2088	1251	5	50	50	NUM
admet-2088	1251	6	(	(	PUNCT
admet-2088	1251	7	2023	2023	NUM
admet-2088	1251	8	)	)	PUNCT
admet-2088	1251	9	102710	102710	NUM
admet-2088	1251	10	.	.	PUNCT
admet-2088	1252	1	https://doi.org/10.1016/j.bcab.2023.102710	https://doi.org/10.1016/j.bcab.2023.102710	ADJ
admet-2088	1252	2	.	.	PUNCT
admet-2088	1253	1	[	[	X
admet-2088	1253	2	135	135	NUM
admet-2088	1253	3	]	]	X
admet-2088	1253	4	s.s	s.s	PROPN
admet-2088	1253	5	.	.	PROPN
admet-2088	1253	6	deshpande	deshpande	PROPN
admet-2088	1253	7	,	,	PUNCT
admet-2088	1253	8	d.k	d.k	PROPN
admet-2088	1253	9	.	.	PROPN
admet-2088	1253	10	veeragoni	veeragoni	PROPN
admet-2088	1253	11	,	,	PUNCT
admet-2088	1253	12	l.	l.	PROPN
admet-2088	1253	13	kongari	kongari	PROPN
admet-2088	1253	14	,	,	PUNCT
admet-2088	1253	15	j.	j.	PROPN
admet-2088	1253	16	mamilla	mamilla	PROPN
admet-2088	1253	17	,	,	PUNCT
admet-2088	1253	18	s.	s.	PROPN
admet-2088	1253	19	misra	misra	PROPN
admet-2088	1253	20	.	.	PUNCT
admet-2088	1254	1	synthesis	synthesis	NOUN
admet-2088	1254	2	of	of	ADP
admet-2088	1254	3	biocompatible	biocompatible	ADJ
admet-2088	1254	4	chitosan	chitosan	NOUN
admet-2088	1254	5	coated	coat	VERB
admet-2088	1254	6	tio2	tio2	NOUN
admet-2088	1254	7	-	-	PUNCT
admet-2088	1254	8	curcumin	curcumin	NOUN
admet-2088	1254	9	nanocomposites	nanocomposite	NOUN
admet-2088	1254	10	shows	show	VERB
admet-2088	1254	11	potent	potent	ADJ
admet-2088	1254	12	anticancer	anticancer	NOUN
admet-2088	1254	13	activity	activity	NOUN
admet-2088	1254	14	towards	towards	ADP
admet-2088	1254	15	melanoma	melanoma	NOUN
admet-2088	1254	16	cancer	cancer	NOUN
admet-2088	1254	17	cells	cell	NOUN
admet-2088	1254	18	.	.	PUNCT
admet-2088	1255	1	journal	journal	NOUN
admet-2088	1255	2	of	of	ADP
admet-2088	1255	3	drug	drug	NOUN
admet-2088	1255	4	delivery	delivery	NOUN
admet-2088	1255	5	science	science	NOUN
admet-2088	1255	6	and	and	CCONJ
admet-2088	1255	7	technology	technology	NOUN
admet-2088	1255	8	85	85	NUM
admet-2088	1255	9	(	(	PUNCT
admet-2088	1255	10	2023	2023	NUM
admet-2088	1255	11	)	)	PUNCT
admet-2088	1255	12	104592	104592	NUM
admet-2088	1255	13	.	.	PUNCT
admet-2088	1256	1	https://doi.org/10.1016/j.jddst.2023.104592	https://doi.org/10.1016/j.jddst.2023.104592	NOUN
admet-2088	1256	2	.	.	PUNCT
admet-2088	1257	1	[	[	X
admet-2088	1257	2	136	136	NUM
admet-2088	1257	3	]	]	X
admet-2088	1257	4	k.j	k.j	PROPN
admet-2088	1257	5	.	.	PROPN
admet-2088	1257	6	widder	widder	PROPN
admet-2088	1257	7	,	,	PUNCT
admet-2088	1257	8	p.a	p.a	PROPN
admet-2088	1257	9	.	.	PROPN
admet-2088	1257	10	marino	marino	PROPN
admet-2088	1257	11	,	,	PUNCT
admet-2088	1257	12	r.m	r.m	PROPN
admet-2088	1257	13	.	.	PROPN
admet-2088	1257	14	morris	morris	PROPN
admet-2088	1257	15	,	,	PUNCT
admet-2088	1257	16	d.p	d.p	PROPN
admet-2088	1257	17	.	.	PUNCT
admet-2088	1257	18	howard	howard	PROPN
admet-2088	1257	19	,	,	PUNCT
admet-2088	1257	20	g.a	g.a	PROPN
admet-2088	1257	21	.	.	PROPN
admet-2088	1257	22	poore	poore	PROPN
admet-2088	1257	23	,	,	PUNCT
admet-2088	1257	24	a.e	a.e	PROPN
admet-2088	1257	25	.	.	PROPN
admet-2088	1257	26	senyei	senyei	NOUN
admet-2088	1257	27	.	.	PUNCT
admet-2088	1258	1	selective	selective	ADJ
admet-2088	1258	2	targeting	targeting	NOUN
admet-2088	1258	3	of	of	ADP
admet-2088	1258	4	magnetic	magnetic	ADJ
admet-2088	1258	5	albumin	albumin	ADJ
admet-2088	1258	6	microspheres	microsphere	NOUN
admet-2088	1258	7	to	to	ADP
admet-2088	1258	8	the	the	DET
admet-2088	1258	9	yoshida	yoshida	PROPN
admet-2088	1258	10	sarcoma	sarcoma	NOUN
admet-2088	1258	11	:	:	PUNCT
admet-2088	1258	12	ultrastructural	ultrastructural	ADJ
admet-2088	1258	13	evaluation	evaluation	NOUN
admet-2088	1258	14	of	of	ADP
admet-2088	1258	15	microsphere	microsphere	PROPN
admet-2088	1258	16	disposition	disposition	NOUN
admet-2088	1258	17	.	.	PUNCT
admet-2088	1259	1	european	european	ADJ
admet-2088	1259	2	journal	journal	PROPN
admet-2088	1259	3	of	of	ADP
admet-2088	1259	4	cancer	cancer	NOUN
admet-2088	1259	5	and	and	CCONJ
admet-2088	1259	6	clinical	clinical	ADJ
admet-2088	1259	7	oncology	oncology	NOUN
admet-2088	1259	8	19	19	NUM
admet-2088	1259	9	(	(	PUNCT
admet-2088	1259	10	1983	1983	NUM
admet-2088	1259	11	)	)	PUNCT
admet-2088	1259	12	141	141	NUM
admet-2088	1259	13	-	-	SYM
admet-2088	1259	14	147	147	NUM
admet-2088	1259	15	.	.	PUNCT
admet-2088	1260	1	https://doi.org/10.1016/0277-5379(83)90409-1	https://doi.org/10.1016/0277-5379(83)90409-1	NUM
admet-2088	1260	2	.	.	PUNCT
admet-2088	1261	1	[	[	X
admet-2088	1261	2	137	137	NUM
admet-2088	1261	3	]	]	X
admet-2088	1261	4	p.b	p.b	PROPN
admet-2088	1261	5	.	.	PROPN
admet-2088	1261	6	santhosh	santhosh	PROPN
admet-2088	1261	7	,	,	PUNCT
admet-2088	1261	8	n.p	n.p	PROPN
admet-2088	1261	9	.	.	PROPN
admet-2088	1261	10	ulrih	ulrih	NOUN
admet-2088	1261	11	.	.	PUNCT
admet-2088	1262	1	multifunctional	multifunctional	ADJ
admet-2088	1262	2	superparamagnetic	superparamagnetic	ADJ
admet-2088	1262	3	iron	iron	NOUN
admet-2088	1262	4	oxide	oxide	NOUN
admet-2088	1262	5	nanoparticles	nanoparticle	NOUN
admet-2088	1262	6	:	:	PUNCT
admet-2088	1262	7	promising	promise	VERB
admet-2088	1262	8	tools	tool	NOUN
admet-2088	1262	9	in	in	ADP
admet-2088	1262	10	cancer	cancer	NOUN
admet-2088	1262	11	theranostics	theranostic	NOUN
admet-2088	1262	12	.	.	PUNCT
admet-2088	1263	1	cancer	cancer	NOUN
admet-2088	1263	2	letters	letter	NOUN
admet-2088	1263	3	336	336	NUM
admet-2088	1263	4	(	(	PUNCT
admet-2088	1263	5	2013	2013	NUM
admet-2088	1263	6	)	)	PUNCT
admet-2088	1263	7	8	8	NUM
admet-2088	1263	8	-	-	SYM
admet-2088	1263	9	17	17	NUM
admet-2088	1263	10	.	.	PUNCT
admet-2088	1264	1	https://doi:10.1016	https://doi:10.1016	PROPN
admet-2088	1264	2	/	/	SYM
admet-2088	1264	3	j.canlet.2013.04.032	j.canlet.2013.04.032	PROPN
admet-2088	1264	4	.	.	PUNCT
admet-2088	1265	1	[	[	X
admet-2088	1265	2	138	138	NUM
admet-2088	1265	3	]	]	X
admet-2088	1265	4	c.	c.	PROPN
admet-2088	1265	5	plank	plank	PROPN
admet-2088	1265	6	.	.	PUNCT
admet-2088	1266	1	nanomedicine	nanomedicine	NOUN
admet-2088	1266	2	:	:	PUNCT
admet-2088	1266	3	silence	silence	VERB
admet-2088	1266	4	the	the	DET
admet-2088	1266	5	target	target	NOUN
admet-2088	1266	6	.	.	PUNCT
admet-2088	1267	1	nature	nature	PROPN
admet-2088	1267	2	nanotechnology	nanotechnology	PROPN
admet-2088	1267	3	4	4	NUM
admet-2088	1267	4	(	(	PUNCT
admet-2088	1267	5	2009	2009	NUM
admet-2088	1267	6	)	)	PUNCT
admet-2088	1267	7	544	544	NUM
admet-2088	1267	8	-	-	SYM
admet-2088	1267	9	545	545	NUM
admet-2088	1267	10	.	.	PUNCT
admet-2088	1268	1	https://doi.org/10.1038/nnano.2009.251	https://doi.org/10.1038/nnano.2009.251	PROPN
admet-2088	1268	2	.	.	PUNCT
admet-2088	1269	1	[	[	X
admet-2088	1269	2	139	139	NUM
admet-2088	1269	3	]	]	X
admet-2088	1269	4	m.	m.	NOUN
admet-2088	1269	5	rajan	rajan	PROPN
admet-2088	1269	6	,	,	PUNCT
admet-2088	1269	7	p.	p.	PROPN
admet-2088	1269	8	krishnan	krishnan	PROPN
admet-2088	1269	9	,	,	PUNCT
admet-2088	1269	10	p.	p.	NOUN
admet-2088	1269	11	pradeepkumar	pradeepkumar	PROPN
admet-2088	1269	12	,	,	PUNCT
admet-2088	1269	13	m.	m.	NOUN
admet-2088	1269	14	jeyanthinath	jeyanthinath	PROPN
admet-2088	1269	15	,	,	PUNCT
admet-2088	1269	16	m.	m.	NOUN
admet-2088	1269	17	jeyaraj	jeyaraj	PROPN
admet-2088	1269	18	,	,	PUNCT
admet-2088	1269	19	m.p	m.p	PROPN
admet-2088	1269	20	.	.	PROPN
admet-2088	1269	21	ling	ling	PROPN
admet-2088	1269	22	,	,	PUNCT
admet-2088	1269	23	p.	p.	PROPN
admet-2088	1269	24	arulselvan	arulselvan	PROPN
admet-2088	1269	25	,	,	PUNCT
admet-2088	1269	26	a.	a.	PROPN
admet-2088	1269	27	higuchi	higuchi	PROPN
admet-2088	1269	28	,	,	PUNCT
admet-2088	1269	29	m.a	m.a	PROPN
admet-2088	1269	30	.	.	PROPN
admet-2088	1269	31	munusamy	munusamy	PROPN
admet-2088	1269	32	,	,	PUNCT
admet-2088	1269	33	r.	r.	PROPN
admet-2088	1269	34	arumugam	arumugam	PROPN
admet-2088	1269	35	,	,	PUNCT
admet-2088	1269	36	g.	g.	PROPN
admet-2088	1269	37	benelli	benelli	PROPN
admet-2088	1269	38	,	,	PUNCT
admet-2088	1269	39	k.	k.	PROPN
admet-2088	1269	40	muruganmo	muruganmo	PROPN
admet-2088	1269	41	,	,	PUNCT
admet-2088	1269	42	s.s	s.s	PROPN
admet-2088	1269	43	.	.	PROPN
admet-2088	1269	44	kumar	kumar	PROPN
admet-2088	1269	45	.	.	PROPN
admet-2088	1269	46	magnetochemotherapy	magnetochemotherapy	PROPN
admet-2088	1269	47	for	for	ADP
admet-2088	1269	48	cervical	cervical	ADJ
admet-2088	1269	49	cancer	cancer	NOUN
admet-2088	1269	50	treatment	treatment	NOUN
admet-2088	1269	51	with	with	ADP
admet-2088	1269	52	camptothecin	camptothecin	NOUN
admet-2088	1269	53	loaded	load	VERB
admet-2088	1269	54	fe3o4	fe3o4	NOUN
admet-2088	1269	55	functionalized	functionalized	ADJ
admet-2088	1269	56	βcyclodextrin	βcyclodextrin	NOUN
admet-2088	1269	57	nanovehicle	nanovehicle	NOUN
admet-2088	1269	58	.	.	PUNCT
admet-2088	1270	1	rsc	rsc	PROPN
admet-2088	1270	2	advances	advance	VERB
admet-2088	1270	3	7	7	NUM
admet-2088	1270	4	(	(	PUNCT
admet-2088	1270	5	2017	2017	NUM
admet-2088	1270	6	)	)	PUNCT
admet-2088	1270	7	46271	46271	NUM
admet-2088	1270	8	-	-	SYM
admet-2088	1270	9	46285	46285	NUM
admet-2088	1270	10	,	,	PUNCT
admet-2088	1270	11	https://doi.org/10.1039/c7ra06615e	https://doi.org/10.1039/c7ra06615e	PROPN
admet-2088	1270	12	.	.	PUNCT
admet-2088	1271	1	[	[	X
admet-2088	1271	2	140	140	NUM
admet-2088	1271	3	]	]	X
admet-2088	1271	4	w.	w.	PROPN
admet-2088	1271	5	zheng	zheng	PROPN
admet-2088	1271	6	,	,	PUNCT
admet-2088	1271	7	q.	q.	PROPN
admet-2088	1271	8	zhou	zhou	PROPN
admet-2088	1271	9	,	,	PUNCT
admet-2088	1271	10	c.	c.	PROPN
admet-2088	1271	11	yuan	yuan	PROPN
admet-2088	1271	12	.	.	PUNCT
admet-2088	1272	1	nanoparticles	nanoparticle	NOUN
admet-2088	1272	2	for	for	ADP
admet-2088	1272	3	oral	oral	ADJ
admet-2088	1272	4	cancer	cancer	NOUN
admet-2088	1272	5	diagnosis	diagnosis	NOUN
admet-2088	1272	6	and	and	CCONJ
admet-2088	1272	7	therapy	therapy	NOUN
admet-2088	1272	8	.	.	PUNCT
admet-2088	1273	1	bioinorganic	bioinorganic	ADJ
admet-2088	1273	2	chemistry	chemistry	NOUN
admet-2088	1273	3	and	and	CCONJ
admet-2088	1273	4	applications	application	NOUN
admet-2088	1273	5	2021	2021	NUM
admet-2088	1273	6	(	(	PUNCT
admet-2088	1273	7	2021	2021	NUM
admet-2088	1273	8	)	)	PUNCT
admet-2088	1273	9	1	1	NUM
admet-2088	1273	10	-	-	SYM
admet-2088	1273	11	14	14	NUM
admet-2088	1273	12	.	.	PUNCT
admet-2088	1274	1	https://doi.org/10.1155/2021/9977131	https://doi.org/10.1155/2021/9977131	PROPN
admet-2088	1274	2	.	.	PUNCT
admet-2088	1275	1	https://doi.org/10.1038/nm.2933	https://doi.org/10.1038/nm.2933	PROPN
admet-2088	1275	2	https://doi.org/0.1038/nnano.2016.164	https://doi.org/0.1038/nnano.2016.164	NOUN
admet-2088	1275	3	https://doi.org/10.1016/j.nano.2015.11.013	https://doi.org/10.1016/j.nano.2015.11.013	NOUN
admet-2088	1275	4	https://doi.org/10.1016/j.cej.2022.140175	https://doi.org/10.1016/j.cej.2022.140175	PROPN
admet-2088	1275	5	https://doi.org/10.1016/j.ejpb.2014.11.022	https://doi.org/10.1016/j.ejpb.2014.11.022	NOUN
admet-2088	1275	6	https://doi.org/10.1016/j.tox.2005.05.007	https://doi.org/10.1016/j.tox.2005.05.007	ADJ
admet-2088	1275	7	https://doi.org/10.2147/ijn.s249441	https://doi.org/10.2147/ijn.s249441	PROPN
admet-2088	1275	8	https://doi.org/10.1002/adma.201807660	https://doi.org/10.1002/adma.201807660	NOUN
admet-2088	1275	9	https://doi.org/10.1016/j.bcab.2023.102710	https://doi.org/10.1016/j.bcab.2023.102710	ADJ
admet-2088	1275	10	https://doi.org/10.1016/j.jddst.2023.104592	https://doi.org/10.1016/j.jddst.2023.104592	NOUN
admet-2088	1275	11	https://doi.org/10.1016/0277-5379(83)90409-1	https://doi.org/10.1016/0277-5379(83)90409-1	PROPN
admet-2088	1275	12	https://doi:10.1016	https://doi:10.1016	PROPN
admet-2088	1275	13	/	/	SYM
admet-2088	1275	14	j.canlet.2013.04.032	j.canlet.2013.04.032	PROPN
admet-2088	1275	15	https://doi.org/10.1038/nnano.2009.251	https://doi.org/10.1038/nnano.2009.251	PROPN
admet-2088	1276	1	https://doi.org/10.1039/c7ra06615e	https://doi.org/10.1039/c7ra06615e	PROPN
admet-2088	1276	2	https://doi.org/10.1155/2021/9977131	https://doi.org/10.1155/2021/9977131	PROPN
admet-2088	1276	3	admet	admet	PROPN
admet-2088	1276	4	&	&	CCONJ
admet-2088	1276	5	dmpk	dmpk	PROPN
admet-2088	1276	6	12(1	12(1	PROPN
admet-2088	1276	7	)	)	PUNCT
admet-2088	1276	8	(	(	PUNCT
admet-2088	1276	9	2024	2024	NUM
admet-2088	1276	10	)	)	PUNCT
admet-2088	1276	11	107	107	NUM
admet-2088	1276	12	-	-	SYM
admet-2088	1276	13	150	150	NUM
admet-2088	1276	14	nanomaterial	nanomaterial	NOUN
admet-2088	1276	15	-	-	PUNCT
admet-2088	1276	16	based	base	VERB
admet-2088	1276	17	drug	drug	NOUN
admet-2088	1276	18	delivery	delivery	NOUN
admet-2088	1276	19	systems	system	NOUN
admet-2088	1276	20	for	for	ADP
admet-2088	1276	21	melanoma	melanoma	NOUN
admet-2088	1276	22	therapy	therapy	NOUN
admet-2088	1276	23	doi	doi	NOUN
admet-2088	1276	24	:	:	PUNCT
admet-2088	1276	25	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	1276	26	145	145	NUM
admet-2088	1276	27	[	[	X
admet-2088	1276	28	141	141	NUM
admet-2088	1276	29	]	]	PUNCT
admet-2088	1276	30	h.	h.	PROPN
admet-2088	1276	31	geng	geng	PROPN
admet-2088	1276	32	,	,	PUNCT
admet-2088	1276	33	q.	q.	PROPN
admet-2088	1276	34	dai	dai	PROPN
admet-2088	1276	35	,	,	PUNCT
admet-2088	1276	36	h.	h.	PROPN
admet-2088	1276	37	sun	sun	PROPN
admet-2088	1276	38	,	,	PUNCT
admet-2088	1276	39	l.	l.	PROPN
admet-2088	1276	40	zhuang	zhuang	PROPN
admet-2088	1276	41	,	,	PUNCT
admet-2088	1276	42	a.	a.	NOUN
admet-2088	1276	43	song	song	PROPN
admet-2088	1276	44	,	,	PUNCT
admet-2088	1276	45	f.	f.	PROPN
admet-2088	1276	46	caruso	caruso	PROPN
admet-2088	1276	47	,	,	PUNCT
admet-2088	1276	48	j.	j.	PROPN
admet-2088	1276	49	hao	hao	PROPN
admet-2088	1276	50	,	,	PUNCT
admet-2088	1276	51	j.	j.	PROPN
admet-2088	1276	52	cui	cui	PROPN
admet-2088	1276	53	.	.	PUNCT
admet-2088	1277	1	injectable	injectable	ADJ
admet-2088	1277	2	and	and	CCONJ
admet-2088	1277	3	sprayable	sprayable	ADJ
admet-2088	1277	4	polyphenol	polyphenol	NOUN
admet-2088	1277	5	-	-	PUNCT
admet-2088	1277	6	based	base	VERB
admet-2088	1277	7	hydrogels	hydrogel	NOUN
admet-2088	1277	8	for	for	ADP
admet-2088	1277	9	controlling	control	VERB
admet-2088	1277	10	hemostasis	hemostasis	NOUN
admet-2088	1277	11	.	.	PUNCT
admet-2088	1278	1	acs	acs	PROPN
admet-2088	1278	2	applied	apply	VERB
admet-2088	1278	3	bio	bio	NOUN
admet-2088	1278	4	materials	material	NOUN
admet-2088	1278	5	3	3	NUM
admet-2088	1278	6	(	(	PUNCT
admet-2088	1278	7	2020	2020	NUM
admet-2088	1278	8	)	)	PUNCT
admet-2088	1278	9	12581266	12581266	NUM
admet-2088	1278	10	.	.	PUNCT
admet-2088	1279	1	https://doi.org/10.1021/acsabm.9b01138	https://doi.org/10.1021/acsabm.9b01138	PROPN
admet-2088	1279	2	.	.	PUNCT
admet-2088	1280	1	[	[	X
admet-2088	1280	2	142	142	NUM
admet-2088	1280	3	]	]	PUNCT
admet-2088	1280	4	b.	b.	PROPN
admet-2088	1280	5	zhang	zhang	PROPN
admet-2088	1280	6	,	,	PUNCT
admet-2088	1280	7	r.	r.	PROPN
admet-2088	1280	8	yao	yao	PROPN
admet-2088	1280	9	,	,	PUNCT
admet-2088	1280	10	c.	c.	PROPN
admet-2088	1280	11	hu	hu	PROPN
admet-2088	1280	12	,	,	PUNCT
admet-2088	1280	13	m.f	m.f	PROPN
admet-2088	1280	14	.	.	PROPN
admet-2088	1280	15	maitz	maitz	PROPN
admet-2088	1280	16	,	,	PUNCT
admet-2088	1280	17	h.	h.	PROPN
admet-2088	1280	18	wu	wu	PROPN
admet-2088	1280	19	,	,	PUNCT
admet-2088	1280	20	k.	k.	PROPN
admet-2088	1280	21	liu	liu	PROPN
admet-2088	1280	22	,	,	PUNCT
admet-2088	1280	23	l.	l.	PROPN
admet-2088	1280	24	yang	yang	PROPN
admet-2088	1280	25	,	,	PUNCT
admet-2088	1280	26	r.	r.	PROPN
admet-2088	1280	27	luo	luo	PROPN
admet-2088	1280	28	,	,	PUNCT
admet-2088	1280	29	y.	y.	PROPN
admet-2088	1280	30	wang	wang	PROPN
admet-2088	1280	31	.	.	PUNCT
admet-2088	1281	1	epigallocatechin	epigallocatechin	PROPN
admet-2088	1281	2	gallate	gallate	PROPN
admet-2088	1281	3	mediated	mediate	VERB
admet-2088	1281	4	sandwich	sandwich	NOUN
admet-2088	1281	5	-	-	PUNCT
admet-2088	1281	6	like	like	ADJ
admet-2088	1281	7	coating	coating	NOUN
admet-2088	1281	8	for	for	ADP
admet-2088	1281	9	mimicking	mimic	VERB
admet-2088	1281	10	endothelium	endothelium	NOUN
admet-2088	1281	11	with	with	ADP
admet-2088	1281	12	sustained	sustained	ADJ
admet-2088	1281	13	therapeutic	therapeutic	ADJ
admet-2088	1281	14	nitric	nitric	ADJ
admet-2088	1281	15	oxide	oxide	NOUN
admet-2088	1281	16	generation	generation	NOUN
admet-2088	1281	17	and	and	CCONJ
admet-2088	1281	18	heparin	heparin	ADJ
admet-2088	1281	19	release	release	NOUN
admet-2088	1281	20	.	.	PUNCT
admet-2088	1282	1	biomaterials	biomaterial	NOUN
admet-2088	1282	2	269	269	NUM
admet-2088	1282	3	(	(	PUNCT
admet-2088	1282	4	2020	2020	NUM
admet-2088	1282	5	)	)	PUNCT
admet-2088	1282	6	120418	120418	NUM
admet-2088	1282	7	.	.	PUNCT
admet-2088	1283	1	https://doi:10.1016	https://doi:10.1016	PROPN
admet-2088	1283	2	/	/	SYM
admet-2088	1283	3	j.biomaterials.2020.120418	j.biomaterials.2020.120418	PROPN
admet-2088	1283	4	.	.	PUNCT
admet-2088	1284	1	[	[	X
admet-2088	1284	2	143	143	X
admet-2088	1284	3	]	]	X
admet-2088	1284	4	j.	j.	PROPN
admet-2088	1284	5	guo	guo	PROPN
admet-2088	1284	6	,	,	PUNCT
admet-2088	1284	7	y.	y.	PROPN
admet-2088	1284	8	ping	ping	PROPN
admet-2088	1284	9	,	,	PUNCT
admet-2088	1284	10	h.	h.	PROPN
admet-2088	1284	11	ejima	ejima	PROPN
admet-2088	1284	12	,	,	PUNCT
admet-2088	1284	13	k.	k.	PROPN
admet-2088	1284	14	alt	alt	PROPN
admet-2088	1284	15	,	,	PUNCT
admet-2088	1284	16	m.	m.	PROPN
admet-2088	1284	17	meissner	meissner	PROPN
admet-2088	1284	18	,	,	PUNCT
admet-2088	1284	19	j.r	j.r	PROPN
admet-2088	1284	20	.	.	PROPN
admet-2088	1284	21	richardson	richardson	PROPN
admet-2088	1284	22	,	,	PUNCT
admet-2088	1284	23	y.	y.	PROPN
admet-2088	1284	24	yan	yan	PROPN
admet-2088	1284	25	,	,	PUNCT
admet-2088	1284	26	k.	k.	PROPN
admet-2088	1284	27	peter	peter	PROPN
admet-2088	1284	28	,	,	PUNCT
admet-2088	1284	29	d.	d.	PROPN
admet-2088	1284	30	von	von	PROPN
admet-2088	1284	31	elverfeldt	elverfeldt	PROPN
admet-2088	1284	32	,	,	PUNCT
admet-2088	1284	33	c.e	c.e	PROPN
admet-2088	1284	34	.	.	PROPN
admet-2088	1284	35	hagemeyer	hagemeyer	PROPN
admet-2088	1284	36	,	,	PUNCT
admet-2088	1284	37	f.	f.	PROPN
admet-2088	1284	38	caruso	caruso	PROPN
admet-2088	1284	39	.	.	PUNCT
admet-2088	1285	1	engineering	engineering	NOUN
admet-2088	1285	2	multifunctional	multifunctional	ADJ
admet-2088	1285	3	capsules	capsule	NOUN
admet-2088	1285	4	through	through	ADP
admet-2088	1285	5	the	the	DET
admet-2088	1285	6	assembly	assembly	NOUN
admet-2088	1285	7	of	of	ADP
admet-2088	1285	8	metalphenolic	metalphenolic	ADJ
admet-2088	1285	9	networks	network	NOUN
admet-2088	1285	10	”	"	PUNCT
admet-2088	1285	11	.	.	PUNCT
admet-2088	1286	1	angewandte	angewandte	PROPN
admet-2088	1286	2	chemie	chemie	PROPN
admet-2088	1286	3	international	international	PROPN
admet-2088	1286	4	edition	edition	PROPN
admet-2088	1286	5	53	53	NUM
admet-2088	1286	6	(	(	PUNCT
admet-2088	1286	7	2014	2014	NUM
admet-2088	1286	8	)	)	PUNCT
admet-2088	1286	9	5546	5546	NUM
admet-2088	1286	10	-	-	SYM
admet-2088	1286	11	5551	5551	NUM
admet-2088	1286	12	.	.	PUNCT
admet-2088	1287	1	https://doi.org/10.1002/anie.201311136	https://doi.org/10.1002/anie.201311136	NOUN
admet-2088	1287	2	.	.	PUNCT
admet-2088	1288	1	[	[	X
admet-2088	1288	2	144	144	NUM
admet-2088	1288	3	]	]	X
admet-2088	1288	4	m.	m.	NOUN
admet-2088	1288	5	mu	mu	PROPN
admet-2088	1288	6	,	,	PUNCT
admet-2088	1288	7	x.	x.	PROPN
admet-2088	1288	8	liang	liang	PROPN
admet-2088	1288	9	,	,	PUNCT
admet-2088	1288	10	d.	d.	PROPN
admet-2088	1288	11	chuan	chuan	PROPN
admet-2088	1288	12	,	,	PUNCT
admet-2088	1288	13	s.	s.	PROPN
admet-2088	1288	14	zhao	zhao	PROPN
admet-2088	1288	15	,	,	PUNCT
admet-2088	1288	16	w.	w.	PROPN
admet-2088	1288	17	yu	yu	PROPN
admet-2088	1288	18	,	,	PUNCT
admet-2088	1288	19	r.	r.	PROPN
admet-2088	1288	20	fan	fan	PROPN
admet-2088	1288	21	,	,	PUNCT
admet-2088	1288	22	a.	a.	PROPN
admet-2088	1288	23	tong	tong	PROPN
admet-2088	1288	24	,	,	PUNCT
admet-2088	1288	25	n.	n.	PROPN
admet-2088	1288	26	zhao	zhao	PROPN
admet-2088	1288	27	,	,	PUNCT
admet-2088	1288	28	b.	b.	PROPN
admet-2088	1288	29	han	han	PROPN
admet-2088	1288	30	,	,	PUNCT
admet-2088	1288	31	g.	g.	PROPN
admet-2088	1288	32	guo	guo	PROPN
admet-2088	1288	33	.	.	PUNCT
admet-2088	1289	1	chitosan	chitosan	PROPN
admet-2088	1289	2	coated	coat	VERB
admet-2088	1289	3	ph	ph	ADJ
admet-2088	1289	4	-	-	PUNCT
admet-2088	1289	5	responsive	responsive	ADJ
admet-2088	1289	6	metal	metal	NOUN
admet-2088	1289	7	-	-	PUNCT
admet-2088	1289	8	polyphenol	polyphenol	NOUN
admet-2088	1289	9	delivery	delivery	NOUN
admet-2088	1289	10	platform	platform	NOUN
admet-2088	1289	11	for	for	ADP
admet-2088	1289	12	melanoma	melanoma	NOUN
admet-2088	1289	13	chemotherapy	chemotherapy	NOUN
admet-2088	1289	14	.	.	PUNCT
admet-2088	1290	1	carbohydrate	carbohydrate	ADJ
admet-2088	1290	2	polymers	polymer	NOUN
admet-2088	1290	3	264	264	NUM
admet-2088	1290	4	(	(	PUNCT
admet-2088	1290	5	2021	2021	NUM
admet-2088	1290	6	)	)	PUNCT
admet-2088	1290	7	118000	118000	NUM
admet-2088	1290	8	.	.	PUNCT
admet-2088	1291	1	https://doi.org/10.1016/j.carbpol.2021.118000	https://doi.org/10.1016/j.carbpol.2021.118000	ADJ
admet-2088	1291	2	.	.	PUNCT
admet-2088	1292	1	[	[	X
admet-2088	1292	2	145	145	NUM
admet-2088	1292	3	]	]	X
admet-2088	1292	4	d.	d.	PROPN
admet-2088	1292	5	chuan	chuan	PROPN
admet-2088	1292	6	,	,	PUNCT
admet-2088	1292	7	h.	h.	PROPN
admet-2088	1292	8	hou	hou	PROPN
admet-2088	1292	9	,	,	PUNCT
admet-2088	1292	10	y.	y.	PROPN
admet-2088	1292	11	wang	wang	PROPN
admet-2088	1292	12	,	,	PUNCT
admet-2088	1292	13	m.	m.	NOUN
admet-2088	1292	14	mu	mu	PROPN
admet-2088	1292	15	,	,	PUNCT
admet-2088	1292	16	j.	j.	PROPN
admet-2088	1292	17	li	li	PROPN
admet-2088	1292	18	,	,	PUNCT
admet-2088	1292	19	y.	y.	PROPN
admet-2088	1292	20	ren	ren	PROPN
admet-2088	1292	21	,	,	PUNCT
admet-2088	1292	22	n.	n.	PROPN
admet-2088	1292	23	zhao	zhao	PROPN
admet-2088	1292	24	,	,	PUNCT
admet-2088	1292	25	b.	b.	PROPN
admet-2088	1292	26	han	han	PROPN
admet-2088	1292	27	,	,	PUNCT
admet-2088	1292	28	h.	h.	PROPN
admet-2088	1292	29	chen	chen	PROPN
admet-2088	1292	30	,	,	PUNCT
admet-2088	1292	31	g.	g.	PROPN
admet-2088	1292	32	guo	guo	PROPN
admet-2088	1292	33	.	.	PUNCT
admet-2088	1293	1	multifunctional	multifunctional	ADJ
admet-2088	1293	2	metal	metal	NOUN
admet-2088	1293	3	-	-	PUNCT
admet-2088	1293	4	polyphenol	polyphenol	NOUN
admet-2088	1293	5	nanocomposite	nanocomposite	NOUN
admet-2088	1293	6	for	for	ADP
admet-2088	1293	7	melanoma	melanoma	NOUN
admet-2088	1293	8	targeted	target	VERB
admet-2088	1293	9	photo	photo	NOUN
admet-2088	1293	10	/	/	SYM
admet-2088	1293	11	chemodynamic	chemodynamic	ADJ
admet-2088	1293	12	synergistic	synergistic	ADJ
admet-2088	1293	13	therapy	therapy	NOUN
admet-2088	1293	14	.	.	PUNCT
admet-2088	1294	1	journal	journal	NOUN
admet-2088	1294	2	of	of	ADP
admet-2088	1294	3	materials	material	NOUN
admet-2088	1294	4	science	science	NOUN
admet-2088	1294	5	&	&	CCONJ
admet-2088	1294	6	technology	technology	PROPN
admet-2088	1294	7	152	152	NUM
admet-2088	1294	8	(	(	PUNCT
admet-2088	1294	9	2023	2023	NUM
admet-2088	1294	10	)	)	PUNCT
admet-2088	1294	11	159	159	NUM
admet-2088	1294	12	-	-	SYM
admet-2088	1294	13	168	168	NUM
admet-2088	1294	14	.	.	PUNCT
admet-2088	1295	1	https://doi.org/10.1016/j.jmst.2022.12.039	https://doi.org/10.1016/j.jmst.2022.12.039	NOUN
admet-2088	1295	2	.	.	PUNCT
admet-2088	1296	1	[	[	X
admet-2088	1296	2	146	146	NUM
admet-2088	1296	3	]	]	X
admet-2088	1296	4	p.	p.	NOUN
admet-2088	1296	5	li	li	PROPN
admet-2088	1296	6	,	,	PUNCT
admet-2088	1296	7	y.	y.	PROPN
admet-2088	1296	8	li	li	PROPN
admet-2088	1296	9	,	,	PUNCT
admet-2088	1296	10	r.	r.	PROPN
admet-2088	1296	11	fu	fu	PROPN
admet-2088	1296	12	,	,	PUNCT
admet-2088	1296	13	z.	z.	PROPN
admet-2088	1296	14	duan	duan	PROPN
admet-2088	1296	15	,	,	PUNCT
admet-2088	1296	16	c.	c.	PROPN
admet-2088	1296	17	zhu	zhu	PROPN
admet-2088	1296	18	,	,	PUNCT
admet-2088	1296	19	d.	d.	PROPN
admet-2088	1296	20	fan	fan	PROPN
admet-2088	1296	21	.	.	PUNCT
admet-2088	1297	1	nirand	nirand	PROPN
admet-2088	1297	2	ph	ph	VERB
admet-2088	1297	3	-	-	PUNCT
admet-2088	1297	4	responsive	responsive	ADJ
admet-2088	1297	5	injectable	injectable	ADJ
admet-2088	1297	6	nanocomposite	nanocomposite	NOUN
admet-2088	1297	7	alginategraft	alginategraft	NOUN
admet-2088	1297	8	-	-	PUNCT
admet-2088	1297	9	dopamine	dopamine	NOUN
admet-2088	1297	10	hydrogel	hydrogel	NOUN
admet-2088	1297	11	for	for	ADP
admet-2088	1297	12	melanoma	melanoma	NOUN
admet-2088	1297	13	suppression	suppression	NOUN
admet-2088	1297	14	and	and	CCONJ
admet-2088	1297	15	wound	wound	NOUN
admet-2088	1297	16	repair	repair	NOUN
admet-2088	1297	17	.	.	PUNCT
admet-2088	1298	1	carbohydrate	carbohydrate	NOUN
admet-2088	1298	2	polymers	polymer	NOUN
admet-2088	1298	3	314	314	NUM
admet-2088	1298	4	(	(	PUNCT
admet-2088	1298	5	2023	2023	NUM
admet-2088	1298	6	)	)	PUNCT
admet-2088	1298	7	120899	120899	NUM
admet-2088	1298	8	.	.	PUNCT
admet-2088	1299	1	https://doi.org/10.1016/j.carbpol.2023.120899	https://doi.org/10.1016/j.carbpol.2023.120899	NOUN
admet-2088	1299	2	.	.	PUNCT
admet-2088	1300	1	[	[	X
admet-2088	1300	2	147	147	NUM
admet-2088	1300	3	]	]	PUNCT
admet-2088	1300	4	s.	s.	PROPN
admet-2088	1300	5	iijima	iijima	PROPN
admet-2088	1300	6	.	.	PUNCT
admet-2088	1301	1	helical	helical	ADJ
admet-2088	1301	2	microtubules	microtubule	NOUN
admet-2088	1301	3	of	of	ADP
admet-2088	1301	4	graphitic	graphitic	ADJ
admet-2088	1301	5	carbon	carbon	NOUN
admet-2088	1301	6	.	.	PUNCT
admet-2088	1302	1	nature	nature	NOUN
admet-2088	1302	2	354	354	NUM
admet-2088	1302	3	(	(	PUNCT
admet-2088	1302	4	1991	1991	NUM
admet-2088	1302	5	)	)	PUNCT
admet-2088	1302	6	56	56	NUM
admet-2088	1302	7	-	-	SYM
admet-2088	1302	8	58	58	NUM
admet-2088	1302	9	.	.	PUNCT
admet-2088	1303	1	https://doi.org/10.1038/354056a0	https://doi.org/10.1038/354056a0	X
admet-2088	1303	2	.	.	PUNCT
admet-2088	1304	1	[	[	X
admet-2088	1304	2	148	148	NUM
admet-2088	1304	3	]	]	PUNCT
admet-2088	1304	4	z.	z.	PROPN
admet-2088	1304	5	liu	liu	PROPN
admet-2088	1304	6	,	,	PUNCT
admet-2088	1304	7	s.	s.	PROPN
admet-2088	1304	8	tabakman	tabakman	PROPN
admet-2088	1304	9	,	,	PUNCT
admet-2088	1304	10	k.	k.	PROPN
admet-2088	1304	11	welsher	welsher	PROPN
admet-2088	1304	12	,	,	PUNCT
admet-2088	1304	13	h.	h.	PROPN
admet-2088	1304	14	dai	dai	PROPN
admet-2088	1304	15	.	.	PROPN
admet-2088	1304	16	carbon	carbon	NOUN
admet-2088	1304	17	nanotubes	nanotube	NOUN
admet-2088	1304	18	in	in	ADP
admet-2088	1304	19	biology	biology	NOUN
admet-2088	1304	20	and	and	CCONJ
admet-2088	1304	21	medicine	medicine	NOUN
admet-2088	1304	22	:	:	PUNCT
admet-2088	1304	23	in	in	ADP
admet-2088	1304	24	vitro	vitro	X
admet-2088	1304	25	and	and	CCONJ
admet-2088	1304	26	in	in	ADP
admet-2088	1304	27	vivo	vivo	ADJ
admet-2088	1304	28	detection	detection	NOUN
admet-2088	1304	29	,	,	PUNCT
admet-2088	1304	30	imaging	imaging	NOUN
admet-2088	1304	31	and	and	CCONJ
admet-2088	1304	32	drug	drug	NOUN
admet-2088	1304	33	delivery	delivery	NOUN
admet-2088	1304	34	.	.	PUNCT
admet-2088	1305	1	nano	nano	NOUN
admet-2088	1305	2	research	research	NOUN
admet-2088	1305	3	2	2	NUM
admet-2088	1305	4	(	(	PUNCT
admet-2088	1305	5	2009	2009	NUM
admet-2088	1305	6	)	)	PUNCT
admet-2088	1305	7	85	85	NUM
admet-2088	1305	8	-	-	SYM
admet-2088	1305	9	120	120	NUM
admet-2088	1305	10	.	.	PUNCT
admet-2088	1305	11	https://doi.org/10.1007/s12274-009-9009-8	https://doi.org/10.1007/s12274-009-9009-8	NUM
admet-2088	1305	12	.	.	PUNCT
admet-2088	1306	1	[	[	X
admet-2088	1306	2	149	149	NUM
admet-2088	1306	3	]	]	PUNCT
admet-2088	1306	4	s.	s.	PROPN
admet-2088	1306	5	peretz	peretz	PROPN
admet-2088	1306	6	,	,	PUNCT
admet-2088	1306	7	o.	o.	PROPN
admet-2088	1306	8	regev	regev	PROPN
admet-2088	1306	9	.	.	PUNCT
admet-2088	1307	1	carbon	carbon	NOUN
admet-2088	1307	2	nanotubes	nanotube	NOUN
admet-2088	1307	3	as	as	ADP
admet-2088	1307	4	nanocarriers	nanocarrier	NOUN
admet-2088	1307	5	in	in	ADP
admet-2088	1307	6	medicine	medicine	NOUN
admet-2088	1307	7	.	.	PUNCT
admet-2088	1308	1	current	current	ADJ
admet-2088	1308	2	opinion	opinion	NOUN
admet-2088	1308	3	in	in	ADP
admet-2088	1308	4	colloid	colloid	PROPN
admet-2088	1308	5	&	&	CCONJ
admet-2088	1308	6	interface	interface	PROPN
admet-2088	1308	7	science	science	NOUN
admet-2088	1308	8	17	17	NUM
admet-2088	1308	9	(	(	PUNCT
admet-2088	1308	10	2012	2012	NUM
admet-2088	1308	11	)	)	PUNCT
admet-2088	1308	12	360	360	NUM
admet-2088	1308	13	-	-	SYM
admet-2088	1308	14	368	368	NUM
admet-2088	1308	15	.	.	PUNCT
admet-2088	1309	1	https://doi.org/10.1016/j.cocis.2012.09.001	https://doi.org/10.1016/j.cocis.2012.09.001	NOUN
admet-2088	1309	2	.	.	PUNCT
admet-2088	1310	1	[	[	X
admet-2088	1310	2	150	150	NUM
admet-2088	1310	3	]	]	X
admet-2088	1310	4	s.k	s.k	PROPN
admet-2088	1310	5	.	.	PROPN
admet-2088	1310	6	smart	smart	ADJ
admet-2088	1310	7	,	,	PUNCT
admet-2088	1310	8	a.i	a.i	PROPN
admet-2088	1310	9	.	.	PROPN
admet-2088	1310	10	cassady	cassady	PROPN
admet-2088	1310	11	,	,	PUNCT
admet-2088	1310	12	g.q	g.q	PROPN
admet-2088	1310	13	.	.	PROPN
admet-2088	1310	14	lu	lu	PROPN
admet-2088	1310	15	,	,	PUNCT
admet-2088	1310	16	d.j	d.j	PROPN
admet-2088	1310	17	.	.	PROPN
admet-2088	1310	18	martin	martin	PROPN
admet-2088	1310	19	.	.	PUNCT
admet-2088	1311	1	the	the	DET
admet-2088	1311	2	biocompatibility	biocompatibility	NOUN
admet-2088	1311	3	of	of	ADP
admet-2088	1311	4	carbon	carbon	NOUN
admet-2088	1311	5	nanotubes	nanotube	NOUN
admet-2088	1311	6	.	.	PUNCT
admet-2088	1312	1	carbon	carbon	NOUN
admet-2088	1312	2	44	44	NUM
admet-2088	1312	3	(	(	PUNCT
admet-2088	1312	4	2006	2006	NUM
admet-2088	1312	5	)	)	PUNCT
admet-2088	1312	6	1034	1034	NUM
admet-2088	1312	7	-	-	SYM
admet-2088	1312	8	1047	1047	NUM
admet-2088	1312	9	.	.	PUNCT
admet-2088	1313	1	https://doi.org/10.1016/j.carbon.2005.10.011	https://doi.org/10.1016/j.carbon.2005.10.011	NOUN
admet-2088	1313	2	.	.	PUNCT
admet-2088	1314	1	[	[	X
admet-2088	1314	2	151	151	NUM
admet-2088	1314	3	]	]	X
admet-2088	1314	4	r.	r.	PROPN
admet-2088	1314	5	parhi	parhi	PROPN
admet-2088	1314	6	.	.	PUNCT
admet-2088	1315	1	development	development	NOUN
admet-2088	1315	2	and	and	CCONJ
admet-2088	1315	3	in	in	ADP
admet-2088	1315	4	vitro	vitro	X
admet-2088	1315	5	evaluation	evaluation	NOUN
admet-2088	1315	6	of	of	ADP
admet-2088	1315	7	etoricoxib	etoricoxib	ADJ
admet-2088	1315	8	loaded	load	VERB
admet-2088	1315	9	transdermal	transdermal	ADJ
admet-2088	1315	10	film	film	NOUN
admet-2088	1315	11	containing	contain	VERB
admet-2088	1315	12	mwcnt	mwcnt	PROPN
admet-2088	1315	13	.	.	PUNCT
admet-2088	1316	1	journal	journal	PROPN
admet-2088	1316	2	of	of	ADP
admet-2088	1316	3	advanced	advanced	ADJ
admet-2088	1316	4	applied	apply	VERB
admet-2088	1316	5	scientific	scientific	ADJ
admet-2088	1316	6	research	research	NOUN
admet-2088	1316	7	4	4	NUM
admet-2088	1316	8	(	(	PUNCT
admet-2088	1316	9	2022	2022	NUM
admet-2088	1316	10	)	)	PUNCT
admet-2088	1316	11	1	1	NUM
admet-2088	1316	12	-	-	SYM
admet-2088	1316	13	8	8	NUM
admet-2088	1316	14	.	.	PUNCT
admet-2088	1317	1	https://doi.org/10.46947/joaasr442022439	https://doi.org/10.46947/joaasr442022439	NOUN
admet-2088	1317	2	.	.	PUNCT
admet-2088	1318	1	[	[	X
admet-2088	1318	2	152	152	NUM
admet-2088	1318	3	]	]	X
admet-2088	1318	4	g.	g.	PROPN
admet-2088	1318	5	cirillo	cirillo	PROPN
admet-2088	1318	6	,	,	PUNCT
admet-2088	1318	7	s.	s.	PROPN
admet-2088	1318	8	hampel	hampel	PROPN
admet-2088	1318	9	,	,	PUNCT
admet-2088	1318	10	u.g	u.g	PROPN
admet-2088	1318	11	.	.	PROPN
admet-2088	1318	12	spizzirri	spizzirri	PROPN
admet-2088	1318	13	,	,	PUNCT
admet-2088	1318	14	o.i	o.i	PROPN
admet-2088	1318	15	.	.	PROPN
admet-2088	1318	16	parisi	parisi	PROPN
admet-2088	1318	17	,	,	PUNCT
admet-2088	1318	18	n.	n.	PROPN
admet-2088	1318	19	picci	picci	PROPN
admet-2088	1318	20	,	,	PUNCT
admet-2088	1318	21	f.	f.	PROPN
admet-2088	1318	22	iemma	iemma	PROPN
admet-2088	1318	23	.	.	PUNCT
admet-2088	1319	1	carbon	carbon	NOUN
admet-2088	1319	2	nanotubes	nanotube	VERB
admet-2088	1319	3	hybrid	hybrid	ADJ
admet-2088	1319	4	hydrogels	hydrogel	NOUN
admet-2088	1319	5	in	in	ADP
admet-2088	1319	6	drug	drug	NOUN
admet-2088	1319	7	delivery	delivery	NOUN
admet-2088	1319	8	:	:	PUNCT
admet-2088	1319	9	a	a	DET
admet-2088	1319	10	perspective	perspective	ADJ
admet-2088	1319	11	review	review	NOUN
admet-2088	1319	12	.	.	PUNCT
admet-2088	1319	13	biomed	biome	VERB
admet-2088	1319	14	research	research	NOUN
admet-2088	1319	15	international	international	PROPN
admet-2088	1319	16	2014	2014	NUM
admet-2088	1319	17	(	(	PUNCT
admet-2088	1319	18	2014	2014	NUM
admet-2088	1319	19	)	)	PUNCT
admet-2088	1319	20	825017	825017	NUM
admet-2088	1319	21	.	.	PUNCT
admet-2088	1320	1	https://doi.org/10.1155/2014/825017	https://doi.org/10.1155/2014/825017	PROPN
admet-2088	1320	2	.	.	PUNCT
admet-2088	1321	1	[	[	X
admet-2088	1321	2	153	153	NUM
admet-2088	1321	3	]	]	PUNCT
admet-2088	1321	4	j.	j.	PROPN
admet-2088	1321	5	saleem	saleem	PROPN
admet-2088	1321	6	,	,	PUNCT
admet-2088	1321	7	l.	l.	PROPN
admet-2088	1321	8	wang	wang	PROPN
admet-2088	1321	9	,	,	PUNCT
admet-2088	1321	10	c.	c.	PROPN
admet-2088	1321	11	chen	chen	PROPN
admet-2088	1321	12	.	.	PUNCT
admet-2088	1322	1	carbon	carbon	NOUN
admet-2088	1322	2	-	-	PUNCT
admet-2088	1322	3	based	base	VERB
admet-2088	1322	4	nanomaterials	nanomaterial	NOUN
admet-2088	1322	5	for	for	ADP
admet-2088	1322	6	cancer	cancer	NOUN
admet-2088	1322	7	therapy	therapy	NOUN
admet-2088	1322	8	via	via	ADP
admet-2088	1322	9	targeting	target	VERB
admet-2088	1322	10	tumor	tumor	NOUN
admet-2088	1322	11	microenvironment	microenvironment	NOUN
admet-2088	1322	12	.	.	PUNCT
admet-2088	1323	1	advanced	advanced	ADJ
admet-2088	1323	2	healthcare	healthcare	NOUN
admet-2088	1323	3	materials	material	NOUN
admet-2088	1323	4	20	20	NUM
admet-2088	1323	5	(	(	PUNCT
admet-2088	1323	6	2018	2018	NUM
admet-2088	1323	7	)	)	PUNCT
admet-2088	1323	8	800525	800525	NUM
admet-2088	1323	9	.	.	PUNCT
admet-2088	1324	1	https://doi.org/10.1002/adhm.201800525	https://doi.org/10.1002/adhm.201800525	X
admet-2088	1324	2	.	.	PUNCT
admet-2088	1325	1	[	[	X
admet-2088	1325	2	154	154	NUM
admet-2088	1325	3	]	]	PUNCT
admet-2088	1325	4	p.	p.	PROPN
admet-2088	1325	5	chaudhuri	chaudhuri	PROPN
admet-2088	1325	6	,	,	PUNCT
admet-2088	1325	7	s.	s.	PROPN
admet-2088	1325	8	soni	soni	PROPN
admet-2088	1325	9	,	,	PUNCT
admet-2088	1325	10	s.	s.	PROPN
admet-2088	1325	11	sengupta	sengupta	PROPN
admet-2088	1325	12	.	.	PUNCT
admet-2088	1326	1	single	single	ADJ
admet-2088	1326	2	-	-	PUNCT
admet-2088	1326	3	walled	wall	VERB
admet-2088	1326	4	carbon	carbon	NOUN
admet-2088	1326	5	nanotube	nanotube	NOUN
admet-2088	1326	6	-	-	PUNCT
admet-2088	1326	7	conjugated	conjugate	VERB
admet-2088	1326	8	chemotherapy	chemotherapy	NOUN
admet-2088	1326	9	exhibits	exhibit	VERB
admet-2088	1326	10	increased	increase	VERB
admet-2088	1326	11	therapeutic	therapeutic	ADJ
admet-2088	1326	12	index	index	NOUN
admet-2088	1326	13	in	in	ADP
admet-2088	1326	14	melanoma	melanoma	NOUN
admet-2088	1326	15	.	.	PUNCT
admet-2088	1327	1	nanotechnology	nanotechnology	NOUN
admet-2088	1327	2	21	21	NUM
admet-2088	1327	3	(	(	PUNCT
admet-2088	1327	4	2010	2010	NUM
admet-2088	1327	5	)	)	PUNCT
admet-2088	1327	6	025100	025100	NUM
admet-2088	1327	7	-	-	PUNCT
admet-2088	1327	8	025102	025102	NUM
admet-2088	1327	9	.	.	PUNCT
admet-2088	1328	1	https://doi.org/10.1088/0957-4484/21/2/025102	https://doi.org/10.1088/0957-4484/21/2/025102	X
admet-2088	1328	2	.	.	PUNCT
admet-2088	1329	1	[	[	X
admet-2088	1329	2	155	155	NUM
admet-2088	1329	3	]	]	X
admet-2088	1329	4	n.	n.	NOUN
admet-2088	1329	5	behzadpour	behzadpour	NOUN
admet-2088	1329	6	,	,	PUNCT
admet-2088	1329	7	a.	a.	NOUN
admet-2088	1329	8	ranjbar	ranjbar	NOUN
admet-2088	1329	9	,	,	PUNCT
admet-2088	1329	10	n.	n.	NOUN
admet-2088	1329	11	azarpira	azarpira	PROPN
admet-2088	1329	12	,	,	PUNCT
admet-2088	1329	13	n.	n.	PROPN
admet-2088	1329	14	sattarahmady	sattarahmady	PROPN
admet-2088	1329	15	.	.	PUNCT
admet-2088	1330	1	development	development	NOUN
admet-2088	1330	2	of	of	ADP
admet-2088	1330	3	a	a	DET
admet-2088	1330	4	composite	composite	NOUN
admet-2088	1330	5	of	of	ADP
admet-2088	1330	6	polypyrrole	polypyrrole	NOUN
admet-2088	1330	7	-	-	PUNCT
admet-2088	1330	8	coated	coat	VERB
admet-2088	1330	9	carbon	carbon	NOUN
admet-2088	1330	10	nanotubes	nanotube	NOUN
admet-2088	1330	11	as	as	ADP
admet-2088	1330	12	a	a	DET
admet-2088	1330	13	sonosensitizer	sonosensitizer	NOUN
admet-2088	1330	14	for	for	ADP
admet-2088	1330	15	treatment	treatment	NOUN
admet-2088	1330	16	of	of	ADP
admet-2088	1330	17	melanoma	melanoma	NOUN
admet-2088	1330	18	cancer	cancer	NOUN
admet-2088	1330	19	under	under	ADP
admet-2088	1330	20	multi	multi	ADJ
admet-2088	1330	21	-	-	ADJ
admet-2088	1330	22	step	step	ADJ
admet-2088	1330	23	ultrasound	ultrasound	NOUN
admet-2088	1330	24	irradiation	irradiation	NOUN
admet-2088	1330	25	.	.	PUNCT
admet-2088	1331	1	ultrasound	ultrasound	NOUN
admet-2088	1331	2	in	in	ADP
admet-2088	1331	3	medicine	medicine	NOUN
admet-2088	1331	4	&	&	CCONJ
admet-2088	1331	5	biology	biology	PROPN
admet-2088	1331	6	46	46	NUM
admet-2088	1331	7	(	(	PUNCT
admet-2088	1331	8	2020	2020	NUM
admet-2088	1331	9	)	)	PUNCT
admet-2088	1331	10	2322	2322	NUM
admet-2088	1331	11	-	-	SYM
admet-2088	1331	12	2334	2334	NUM
admet-2088	1331	13	.	.	PUNCT
admet-2088	1332	1	https://doi.org/10.1016/j.ultrasmedbio.2020.05.003	https://doi.org/10.1016/j.ultrasmedbio.2020.05.003	PROPN
admet-2088	1332	2	.	.	PUNCT
admet-2088	1333	1	[	[	X
admet-2088	1333	2	156	156	NUM
admet-2088	1333	3	]	]	PUNCT
admet-2088	1333	4	j.	j.	PROPN
admet-2088	1333	5	yao	yao	PROPN
admet-2088	1333	6	,	,	PUNCT
admet-2088	1333	7	y.	y.	PROPN
admet-2088	1333	8	sun	sun	PROPN
admet-2088	1333	9	,	,	PUNCT
admet-2088	1333	10	m.	m.	PROPN
admet-2088	1333	11	yang	yang	PROPN
admet-2088	1333	12	,	,	PUNCT
admet-2088	1333	13	y.	y.	PROPN
admet-2088	1333	14	duan	duan	PROPN
admet-2088	1333	15	.	.	PUNCT
admet-2088	1334	1	chemistry	chemistry	PROPN
admet-2088	1334	2	,	,	PUNCT
admet-2088	1334	3	physics	physics	NOUN
admet-2088	1334	4	and	and	CCONJ
admet-2088	1334	5	biology	biology	NOUN
admet-2088	1334	6	of	of	ADP
admet-2088	1334	7	graphene	graphene	NOUN
admet-2088	1334	8	based	base	VERB
admet-2088	1334	9	nanomaterials	nanomaterial	NOUN
admet-2088	1334	10	:	:	PUNCT
admet-2088	1334	11	new	new	ADJ
admet-2088	1334	12	horizons	horizon	NOUN
admet-2088	1334	13	for	for	ADP
admet-2088	1334	14	sensing	sense	VERB
admet-2088	1334	15	,	,	PUNCT
admet-2088	1334	16	imaging	imaging	NOUN
admet-2088	1334	17	and	and	CCONJ
admet-2088	1334	18	medicine	medicine	NOUN
admet-2088	1334	19	.	.	PUNCT
admet-2088	1335	1	journal	journal	NOUN
admet-2088	1335	2	of	of	ADP
admet-2088	1335	3	materials	material	NOUN
admet-2088	1335	4	chemistry	chemistry	NOUN
admet-2088	1335	5	22	22	NUM
admet-2088	1335	6	(	(	PUNCT
admet-2088	1335	7	2012	2012	NUM
admet-2088	1335	8	)	)	PUNCT
admet-2088	1335	9	14313	14313	NUM
admet-2088	1335	10	.	.	PUNCT
admet-2088	1336	1	https://doi.org/10.1039/c2jm31632c	https://doi.org/10.1039/c2jm31632c	PROPN
admet-2088	1336	2	.	.	PUNCT
admet-2088	1336	3	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	PROPN
admet-2088	1336	4	https://doi.org/10.1021/acsabm.9b01138	https://doi.org/10.1021/acsabm.9b01138	PROPN
admet-2088	1336	5	https://doi:10.1016	https://doi:10.1016	PROPN
admet-2088	1336	6	/	/	SYM
admet-2088	1336	7	j.biomaterials.2020.120418	j.biomaterials.2020.120418	PROPN
admet-2088	1336	8	https://doi.org/10.1002/anie.201311136	https://doi.org/10.1002/anie.201311136	NOUN
admet-2088	1336	9	https://doi.org/10.1016/j.carbpol.2021.118000	https://doi.org/10.1016/j.carbpol.2021.118000	ADJ
admet-2088	1336	10	https://doi.org/10.1016/j.jmst.2022.12.039	https://doi.org/10.1016/j.jmst.2022.12.039	NOUN
admet-2088	1336	11	https://doi.org/10.1016/j.carbpol.2023.120899	https://doi.org/10.1016/j.carbpol.2023.120899	VERB
admet-2088	1336	12	https://doi.org/10.1038/354056a0	https://doi.org/10.1038/354056a0	X
admet-2088	1336	13	https://doi.org/10.1007/s12274-009-9009-8	https://doi.org/10.1007/s12274-009-9009-8	NUM
admet-2088	1337	1	https://doi.org/10.1016/j.cocis.2012.09.001	https://doi.org/10.1016/j.cocis.2012.09.001	VERB
admet-2088	1337	2	https://doi.org/10.1016/j.carbon.2005.10.011	https://doi.org/10.1016/j.carbon.2005.10.011	NUM
admet-2088	1337	3	https://doi.org/10.46947/joaasr442022439	https://doi.org/10.46947/joaasr442022439	NOUN
admet-2088	1337	4	https://doi.org/10.1155/2014/825017	https://doi.org/10.1155/2014/825017	NOUN
admet-2088	1337	5	https://doi.org/10.1002/adhm.201800525	https://doi.org/10.1002/adhm.201800525	VERB
admet-2088	1337	6	https://doi.org/10.1088/0957-4484/21/2/025102	https://doi.org/10.1088/0957-4484/21/2/025102	PROPN
admet-2088	1337	7	https://doi.org/10.1016/j.ultrasmedbio.2020.05.003	https://doi.org/10.1016/j.ultrasmedbio.2020.05.003	PROPN
admet-2088	1337	8	https://doi.org/10.1039/c2jm31632c	https://doi.org/10.1039/c2jm31632c	PROPN
admet-2088	1337	9	m.	m.	NOUN
admet-2088	1337	10	kulkarni	kulkarni	PROPN
admet-2088	1337	11	et	et	PROPN
admet-2088	1337	12	al	al	PROPN
admet-2088	1337	13	.	.	PROPN
admet-2088	1337	14	admet	admet	PROPN
admet-2088	1337	15	&	&	CCONJ
admet-2088	1337	16	dmpk	dmpk	PROPN
admet-2088	1337	17	12(1	12(1	PROPN
admet-2088	1337	18	)	)	PUNCT
admet-2088	1337	19	(	(	PUNCT
admet-2088	1337	20	2024	2024	NUM
admet-2088	1337	21	)	)	PUNCT
admet-2088	1337	22	107	107	NUM
admet-2088	1337	23	-	-	SYM
admet-2088	1337	24	150	150	NUM
admet-2088	1337	25	146	146	NUM
admet-2088	1337	26	[	[	X
admet-2088	1337	27	157	157	NUM
admet-2088	1337	28	]	]	PUNCT
admet-2088	1337	29	j.	j.	PROPN
admet-2088	1337	30	liua	liua	PROPN
admet-2088	1337	31	,	,	PUNCT
admet-2088	1337	32	j.	j.	PROPN
admet-2088	1337	33	donga	donga	PROPN
admet-2088	1337	34	,	,	PUNCT
admet-2088	1337	35	t.	t.	PROPN
admet-2088	1337	36	zhangb	zhangb	PROPN
admet-2088	1337	37	,	,	PUNCT
admet-2088	1337	38	q.	q.	PROPN
admet-2088	1337	39	peng	peng	PROPN
admet-2088	1337	40	.	.	PUNCT
admet-2088	1338	1	graphene	graphene	NOUN
admet-2088	1338	2	-	-	PUNCT
admet-2088	1338	3	based	base	VERB
admet-2088	1338	4	nanomaterials	nanomaterial	NOUN
admet-2088	1338	5	and	and	CCONJ
admet-2088	1338	6	their	their	PRON
admet-2088	1338	7	potentials	potential	NOUN
admet-2088	1338	8	in	in	ADP
admet-2088	1338	9	advanced	advanced	ADJ
admet-2088	1338	10	drug	drug	NOUN
admet-2088	1338	11	delivery	delivery	NOUN
admet-2088	1338	12	and	and	CCONJ
admet-2088	1338	13	cancer	cancer	NOUN
admet-2088	1338	14	therapy	therapy	NOUN
admet-2088	1338	15	.	.	PUNCT
admet-2088	1339	1	journal	journal	PROPN
admet-2088	1339	2	of	of	ADP
admet-2088	1339	3	controlled	control	VERB
admet-2088	1339	4	release	release	NOUN
admet-2088	1339	5	286	286	NUM
admet-2088	1339	6	(	(	PUNCT
admet-2088	1339	7	2018	2018	NUM
admet-2088	1339	8	)	)	PUNCT
admet-2088	1339	9	64	64	NUM
admet-2088	1339	10	-	-	SYM
admet-2088	1339	11	73	73	NUM
admet-2088	1339	12	.	.	PUNCT
admet-2088	1340	1	https://doi.org/10.1016/j.jconrel.2018.07.034	https://doi.org/10.1016/j.jconrel.2018.07.034	NOUN
admet-2088	1340	2	.	.	PUNCT
admet-2088	1341	1	[	[	X
admet-2088	1341	2	158	158	X
admet-2088	1341	3	]	]	X
admet-2088	1341	4	j.	j.	PROPN
admet-2088	1341	5	lin	lin	PROPN
admet-2088	1341	6	,	,	PUNCT
admet-2088	1341	7	x.	x.	PROPN
admet-2088	1341	8	chen	chen	PROPN
admet-2088	1341	9	,	,	PUNCT
admet-2088	1341	10	p.	p.	PROPN
admet-2088	1341	11	huang	huang	PROPN
admet-2088	1341	12	.	.	PUNCT
admet-2088	1342	1	graphene	graphene	NOUN
admet-2088	1342	2	-	-	PUNCT
admet-2088	1342	3	based	base	VERB
admet-2088	1342	4	nanomaterials	nanomaterial	NOUN
admet-2088	1342	5	for	for	ADP
admet-2088	1342	6	bioimaging	bioimaging	NOUN
admet-2088	1342	7	.	.	PUNCT
admet-2088	1343	1	advanced	advanced	ADJ
admet-2088	1343	2	drug	drug	NOUN
admet-2088	1343	3	delivery	delivery	NOUN
admet-2088	1343	4	reviews	review	VERB
admet-2088	1343	5	105	105	NUM
admet-2088	1343	6	(	(	PUNCT
admet-2088	1343	7	2016	2016	NUM
admet-2088	1343	8	)	)	PUNCT
admet-2088	1343	9	242	242	NUM
admet-2088	1343	10	-	-	SYM
admet-2088	1343	11	254	254	NUM
admet-2088	1343	12	.	.	PUNCT
admet-2088	1344	1	https://doi.org/10.1016/j.addr.2016.05.013	https://doi.org/10.1016/j.addr.2016.05.013	PROPN
admet-2088	1344	2	.	.	PUNCT
admet-2088	1345	1	[	[	X
admet-2088	1345	2	159	159	NUM
admet-2088	1345	3	]	]	X
admet-2088	1345	4	w.s	w.s	PROPN
admet-2088	1345	5	.	.	PROPN
admet-2088	1345	6	hummers	hummer	NOUN
admet-2088	1345	7	,	,	PUNCT
admet-2088	1345	8	r.e	r.e	PROPN
admet-2088	1345	9	.	.	PROPN
admet-2088	1345	10	offeman	offeman	PROPN
admet-2088	1345	11	.	.	PUNCT
admet-2088	1346	1	preparation	preparation	NOUN
admet-2088	1346	2	of	of	ADP
admet-2088	1346	3	graphitic	graphitic	ADJ
admet-2088	1346	4	oxide	oxide	NOUN
admet-2088	1346	5	.	.	PUNCT
admet-2088	1347	1	journal	journal	NOUN
admet-2088	1347	2	of	of	ADP
admet-2088	1347	3	the	the	DET
admet-2088	1347	4	american	american	PROPN
admet-2088	1347	5	chemical	chemical	PROPN
admet-2088	1347	6	society	society	PROPN
admet-2088	1347	7	80	80	NUM
admet-2088	1347	8	(	(	PUNCT
admet-2088	1347	9	1958	1958	NUM
admet-2088	1347	10	)	)	PUNCT
admet-2088	1347	11	1339	1339	NUM
admet-2088	1347	12	.	.	PUNCT
admet-2088	1348	1	https://doi.org/10.1021/ja01539a017	https://doi.org/10.1021/ja01539a017	X
admet-2088	1348	2	.	.	PUNCT
admet-2088	1349	1	[	[	X
admet-2088	1349	2	160	160	NUM
admet-2088	1349	3	]	]	PUNCT
admet-2088	1349	4	s.	s.	PROPN
admet-2088	1349	5	you	you	PRON
admet-2088	1349	6	,	,	PUNCT
admet-2088	1349	7	j.	j.	PROPN
admet-2088	1349	8	yu	yu	PROPN
admet-2088	1349	9	,	,	PUNCT
admet-2088	1349	10	b.	b.	PROPN
admet-2088	1349	11	sundqvist	sundqvist	PROPN
admet-2088	1349	12	,	,	PUNCT
admet-2088	1349	13	a.v	a.v	PROPN
admet-2088	1349	14	.	.	PROPN
admet-2088	1349	15	talyzin	talyzin	PROPN
admet-2088	1349	16	.	.	PUNCT
admet-2088	1350	1	solvation	solvation	NOUN
admet-2088	1350	2	of	of	ADP
admet-2088	1350	3	graphite	graphite	NOUN
admet-2088	1350	4	oxide	oxide	NOUN
admet-2088	1350	5	in	in	ADP
admet-2088	1350	6	water	water	NOUN
admet-2088	1350	7	–	–	PUNCT
admet-2088	1350	8	methanol	methanol	NOUN
admet-2088	1350	9	binary	binary	ADJ
admet-2088	1350	10	polar	polar	ADJ
admet-2088	1350	11	solvents	solvent	NOUN
admet-2088	1350	12	.	.	PUNCT
admet-2088	1351	1	physica	physica	PROPN
admet-2088	1351	2	status	status	PROPN
admet-2088	1351	3	solidi	solidi	PROPN
admet-2088	1351	4	b	b	PROPN
admet-2088	1351	5	249	249	NUM
admet-2088	1351	6	(	(	PUNCT
admet-2088	1351	7	2012	2012	NUM
admet-2088	1351	8	)	)	PUNCT
admet-2088	1351	9	2568	2568	NUM
admet-2088	1351	10	-	-	SYM
admet-2088	1351	11	2571	2571	NUM
admet-2088	1351	12	.	.	PUNCT
admet-2088	1352	1	https://doi.org/10.1002/pssb.201200059	https://doi.org/10.1002/pssb.201200059	PROPN
admet-2088	1352	2	.	.	PUNCT
admet-2088	1353	1	[	[	X
admet-2088	1353	2	161	161	NUM
admet-2088	1353	3	]	]	PUNCT
admet-2088	1353	4	s.	s.	PROPN
admet-2088	1353	5	hermanová	hermanová	PROPN
admet-2088	1353	6	,	,	PUNCT
admet-2088	1353	7	m.	m.	NOUN
admet-2088	1353	8	zarevúcká	zarevúcká	PROPN
admet-2088	1353	9	,	,	PUNCT
admet-2088	1353	10	d.	d.	PROPN
admet-2088	1353	11	bouša	bouša	PROPN
admet-2088	1353	12	,	,	PUNCT
admet-2088	1353	13	m.	m.	PROPN
admet-2088	1353	14	pumera	pumera	PROPN
admet-2088	1353	15	,	,	PUNCT
admet-2088	1353	16	z.	z.	PROPN
admet-2088	1353	17	sofer	sofer	PROPN
admet-2088	1353	18	,	,	PUNCT
admet-2088	1353	19	graphene	graphene	ADJ
admet-2088	1353	20	oxide	oxide	NOUN
admet-2088	1353	21	immobilized	immobilize	VERB
admet-2088	1353	22	enzymes	enzyme	NOUN
admet-2088	1353	23	show	show	VERB
admet-2088	1353	24	high	high	ADJ
admet-2088	1353	25	thermal	thermal	ADJ
admet-2088	1353	26	and	and	CCONJ
admet-2088	1353	27	solvent	solvent	ADJ
admet-2088	1353	28	stability	stability	NOUN
admet-2088	1353	29	.	.	PUNCT
admet-2088	1354	1	nanoscale	nanoscale	NOUN
admet-2088	1354	2	7	7	NUM
admet-2088	1354	3	(	(	PUNCT
admet-2088	1354	4	2015	2015	NUM
admet-2088	1354	5	)	)	PUNCT
admet-2088	1354	6	5852	5852	NUM
admet-2088	1354	7	-	-	SYM
admet-2088	1354	8	5858	5858	NUM
admet-2088	1354	9	.	.	PUNCT
admet-2088	1355	1	https://doi.org/10.1039/c5nr00438a	https://doi.org/10.1039/c5nr00438a	NOUN
admet-2088	1355	2	.	.	PUNCT
admet-2088	1356	1	[	[	X
admet-2088	1356	2	162	162	NUM
admet-2088	1356	3	]	]	X
admet-2088	1356	4	c.	c.	PROPN
admet-2088	1356	5	mccallion	mccallion	PROPN
admet-2088	1356	6	,	,	PUNCT
admet-2088	1356	7	j.	j.	PROPN
admet-2088	1356	8	burthem	burthem	PROPN
admet-2088	1356	9	,	,	PUNCT
admet-2088	1356	10	k.	k.	PROPN
admet-2088	1356	11	rees	rees	PROPN
admet-2088	1356	12	-	-	PUNCT
admet-2088	1356	13	unwin	unwin	PROPN
admet-2088	1356	14	,	,	PUNCT
admet-2088	1356	15	a.	a.	NOUN
admet-2088	1356	16	golovanov	golovanov	NOUN
admet-2088	1356	17	,	,	PUNCT
admet-2088	1356	18	a.	a.	NOUN
admet-2088	1356	19	pluen	pluen	NOUN
admet-2088	1356	20	.	.	PUNCT
admet-2088	1357	1	graphene	graphene	VERB
admet-2088	1357	2	in	in	ADP
admet-2088	1357	3	therapeutics	therapeutic	NOUN
admet-2088	1357	4	delivery	delivery	NOUN
admet-2088	1357	5	:	:	PUNCT
admet-2088	1358	1	problems	problem	NOUN
admet-2088	1358	2	,	,	PUNCT
admet-2088	1358	3	solutions	solution	NOUN
admet-2088	1358	4	and	and	CCONJ
admet-2088	1358	5	future	future	ADJ
admet-2088	1358	6	opportunities	opportunity	NOUN
admet-2088	1358	7	.	.	PUNCT
admet-2088	1359	1	european	european	ADJ
admet-2088	1359	2	journal	journal	PROPN
admet-2088	1359	3	of	of	ADP
admet-2088	1359	4	pharmaceutics	pharmaceutic	NOUN
admet-2088	1359	5	and	and	CCONJ
admet-2088	1359	6	biopharmaceutics	biopharmaceutic	NOUN
admet-2088	1359	7	104	104	NUM
admet-2088	1359	8	(	(	PUNCT
admet-2088	1359	9	2016	2016	NUM
admet-2088	1359	10	)	)	PUNCT
admet-2088	1359	11	235	235	NUM
admet-2088	1359	12	-	-	SYM
admet-2088	1359	13	250	250	NUM
admet-2088	1359	14	.	.	PUNCT
admet-2088	1360	1	https://doi.org/10.1016/j.ejpb.2016.04.015	https://doi.org/10.1016/j.ejpb.2016.04.015	NOUN
admet-2088	1360	2	.	.	PUNCT
admet-2088	1361	1	[	[	X
admet-2088	1361	2	163	163	NUM
admet-2088	1361	3	]	]	X
admet-2088	1361	4	y.	y.	PROPN
admet-2088	1361	5	liu	liu	PROPN
admet-2088	1361	6	,	,	PUNCT
admet-2088	1361	7	h.	h.	PROPN
admet-2088	1361	8	zhong	zhong	PROPN
admet-2088	1361	9	,	,	PUNCT
admet-2088	1361	10	y.	y.	PROPN
admet-2088	1361	11	qin	qin	PROPN
admet-2088	1361	12	,	,	PUNCT
admet-2088	1361	13	y.	y.	PROPN
admet-2088	1361	14	zhang	zhang	PROPN
admet-2088	1361	15	,	,	PUNCT
admet-2088	1361	16	x.	x.	PROPN
admet-2088	1361	17	liu	liu	PROPN
admet-2088	1361	18	,	,	PUNCT
admet-2088	1361	19	t.	t.	PROPN
admet-2088	1361	20	zhang	zhang	PROPN
admet-2088	1361	21	.	.	PUNCT
admet-2088	1362	1	non	non	ADJ
admet-2088	1362	2	-	-	ADJ
admet-2088	1362	3	covalent	covalent	ADJ
admet-2088	1362	4	hydrophilization	hydrophilization	NOUN
admet-2088	1362	5	of	of	ADP
admet-2088	1362	6	reduced	reduce	VERB
admet-2088	1362	7	graphene	graphene	NOUN
admet-2088	1362	8	oxide	oxide	NOUN
admet-2088	1362	9	used	use	VERB
admet-2088	1362	10	as	as	ADP
admet-2088	1362	11	a	a	DET
admet-2088	1362	12	paclitaxel	paclitaxel	ADJ
admet-2088	1362	13	vehicle	vehicle	NOUN
admet-2088	1362	14	.	.	PUNCT
admet-2088	1363	1	rsc	rsc	PROPN
admet-2088	1363	2	advances	advance	VERB
admet-2088	1363	3	6	6	NUM
admet-2088	1363	4	(	(	PUNCT
admet-2088	1363	5	2016	2016	NUM
admet-2088	1363	6	)	)	PUNCT
admet-2088	1363	7	30184	30184	NUM
admet-2088	1363	8	-	-	SYM
admet-2088	1363	9	30193	30193	NUM
admet-2088	1363	10	.	.	PUNCT
admet-2088	1364	1	https://doi.org/10.1039/c6ra04349f	https://doi.org/10.1039/c6ra04349f	X
admet-2088	1364	2	.	.	PUNCT
admet-2088	1365	1	[	[	X
admet-2088	1365	2	164	164	NUM
admet-2088	1365	3	]	]	X
admet-2088	1365	4	h.	h.	PROPN
admet-2088	1365	5	chang	chang	PROPN
admet-2088	1365	6	,	,	PUNCT
admet-2088	1365	7	h.	h.	PROPN
admet-2088	1365	8	wu	wu	PROPN
admet-2088	1365	9	.	.	PUNCT
admet-2088	1366	1	graphene	graphene	NOUN
admet-2088	1366	2	-	-	PUNCT
admet-2088	1366	3	based	base	VERB
admet-2088	1366	4	nanomaterials	nanomaterial	NOUN
admet-2088	1366	5	:	:	PUNCT
admet-2088	1366	6	synthesis	synthesis	NOUN
admet-2088	1366	7	,	,	PUNCT
admet-2088	1366	8	properties	property	NOUN
admet-2088	1366	9	,	,	PUNCT
admet-2088	1366	10	and	and	CCONJ
admet-2088	1366	11	optical	optical	ADJ
admet-2088	1366	12	and	and	CCONJ
admet-2088	1366	13	optoelectronic	optoelectronic	ADJ
admet-2088	1366	14	applications	application	NOUN
admet-2088	1366	15	.	.	PUNCT
admet-2088	1367	1	advanced	advanced	ADJ
admet-2088	1367	2	functional	functional	ADJ
admet-2088	1367	3	materials	material	NOUN
admet-2088	1367	4	23	23	NUM
admet-2088	1367	5	(	(	PUNCT
admet-2088	1367	6	2013	2013	NUM
admet-2088	1367	7	)	)	PUNCT
admet-2088	1367	8	1984	1984	NUM
admet-2088	1367	9	-	-	SYM
admet-2088	1367	10	1997	1997	NUM
admet-2088	1367	11	.	.	PUNCT
admet-2088	1368	1	https://doi.org/10.1002/adfm.201202460	https://doi.org/10.1002/adfm.201202460	VERB
admet-2088	1368	2	.	.	PUNCT
admet-2088	1369	1	[	[	X
admet-2088	1369	2	165	165	NUM
admet-2088	1369	3	]	]	X
admet-2088	1369	4	l.	l.	PROPN
admet-2088	1369	5	stobinski	stobinski	PROPN
admet-2088	1369	6	,	,	PUNCT
admet-2088	1369	7	b.	b.	PROPN
admet-2088	1369	8	lesiak	lesiak	PROPN
admet-2088	1369	9	,	,	PUNCT
admet-2088	1369	10	a.	a.	NOUN
admet-2088	1369	11	malolepszy	malolepszy	PROPN
admet-2088	1369	12	,	,	PUNCT
admet-2088	1369	13	m.	m.	NOUN
admet-2088	1369	14	mazurkiewicz	mazurkiewicz	PROPN
admet-2088	1369	15	,	,	PUNCT
admet-2088	1369	16	b.	b.	PROPN
admet-2088	1369	17	mierzwa	mierzwa	PROPN
admet-2088	1369	18	,	,	PUNCT
admet-2088	1369	19	j.	j.	PROPN
admet-2088	1369	20	zemek	zemek	PROPN
admet-2088	1369	21	,	,	PUNCT
admet-2088	1369	22	p.	p.	PROPN
admet-2088	1369	23	jiricek	jiricek	PROPN
admet-2088	1369	24	,	,	PUNCT
admet-2088	1369	25	i.	i.	PROPN
admet-2088	1369	26	bieloshapka	bieloshapka	PROPN
admet-2088	1369	27	.	.	PUNCT
admet-2088	1370	1	graphene	graphene	VERB
admet-2088	1370	2	oxide	oxide	NOUN
admet-2088	1370	3	and	and	CCONJ
admet-2088	1370	4	reduced	reduce	VERB
admet-2088	1370	5	graphene	graphene	NOUN
admet-2088	1370	6	oxide	oxide	NOUN
admet-2088	1370	7	studied	study	VERB
admet-2088	1370	8	by	by	ADP
admet-2088	1370	9	the	the	DET
admet-2088	1370	10	xrd	xrd	PROPN
admet-2088	1370	11	,	,	PUNCT
admet-2088	1370	12	tem	tem	PROPN
admet-2088	1370	13	and	and	CCONJ
admet-2088	1370	14	electron	electron	NOUN
admet-2088	1370	15	spectroscopy	spectroscopy	NOUN
admet-2088	1370	16	methods	method	NOUN
admet-2088	1370	17	.	.	PUNCT
admet-2088	1371	1	journal	journal	PROPN
admet-2088	1371	2	of	of	ADP
admet-2088	1371	3	electron	electron	NOUN
admet-2088	1371	4	spectroscopy	spectroscopy	NOUN
admet-2088	1371	5	and	and	CCONJ
admet-2088	1371	6	related	relate	VERB
admet-2088	1371	7	phenomena	phenomenon	NOUN
admet-2088	1371	8	195	195	NUM
admet-2088	1371	9	(	(	PUNCT
admet-2088	1371	10	2014	2014	NUM
admet-2088	1371	11	)	)	PUNCT
admet-2088	1371	12	145154	145154	NUM
admet-2088	1371	13	.	.	PUNCT
admet-2088	1372	1	https://doi.org/10.1016/j.elspec.2014.07.003	https://doi.org/10.1016/j.elspec.2014.07.003	NOUN
admet-2088	1372	2	.	.	PUNCT
admet-2088	1373	1	[	[	X
admet-2088	1373	2	166	166	NUM
admet-2088	1373	3	]	]	PUNCT
admet-2088	1373	4	m.	m.	NOUN
admet-2088	1373	5	mokhtar	mokhtar	PROPN
admet-2088	1373	6	,	,	PUNCT
admet-2088	1373	7	s.a.e	s.a.e	PROPN
admet-2088	1373	8	.	.	PUNCT
admet-2088	1374	1	enein	enein	PROPN
admet-2088	1374	2	,	,	PUNCT
admet-2088	1374	3	m.y	m.y	PROPN
admet-2088	1374	4	.	.	PROPN
admet-2088	1374	5	hassaan	hassaan	PROPN
admet-2088	1374	6	,	,	PUNCT
admet-2088	1374	7	m.s	m.s	PROPN
admet-2088	1374	8	.	.	PROPN
admet-2088	1374	9	morsy	morsy	PROPN
admet-2088	1374	10	,	,	PUNCT
admet-2088	1374	11	m.h	m.h	PROPN
admet-2088	1374	12	.	.	PROPN
admet-2088	1374	13	khalil	khalil	PROPN
admet-2088	1374	14	.	.	PUNCT
admet-2088	1375	1	thermally	thermally	ADV
admet-2088	1375	2	reduced	reduce	VERB
admet-2088	1375	3	graphene	graphene	ADJ
admet-2088	1375	4	oxide	oxide	NOUN
admet-2088	1375	5	:	:	PUNCT
admet-2088	1375	6	synthesis	synthesis	NOUN
admet-2088	1375	7	,	,	PUNCT
admet-2088	1375	8	structural	structural	ADJ
admet-2088	1375	9	and	and	CCONJ
admet-2088	1375	10	electrical	electrical	ADJ
admet-2088	1375	11	properties	property	NOUN
admet-2088	1375	12	.	.	PUNCT
admet-2088	1376	1	international	international	ADJ
admet-2088	1376	2	journal	journal	NOUN
admet-2088	1376	3	of	of	ADP
admet-2088	1376	4	nanoparticles	nanoparticle	NOUN
admet-2088	1376	5	and	and	CCONJ
admet-2088	1376	6	nanotechnology	nanotechnology	NOUN
admet-2088	1376	7	3	3	NUM
admet-2088	1376	8	(	(	PUNCT
admet-2088	1376	9	2017	2017	NUM
admet-2088	1376	10	)	)	PUNCT
admet-2088	1376	11	008	008	NUM
admet-2088	1376	12	.	.	PUNCT
admet-2088	1376	13	https://doi.org/10.35840/2631-5084/5508	https://doi.org/10.35840/2631-5084/5508	PROPN
admet-2088	1376	14	.	.	PUNCT
admet-2088	1377	1	[	[	X
admet-2088	1377	2	167	167	NUM
admet-2088	1377	3	]	]	PUNCT
admet-2088	1377	4	s.	s.	PROPN
admet-2088	1377	5	nazir	nazir	PROPN
admet-2088	1377	6	,	,	PUNCT
admet-2088	1377	7	md.u.a	md.u.a	PROPN
admet-2088	1377	8	.	.	PUNCT
admet-2088	1377	9	khan	khan	PROPN
admet-2088	1377	10	,	,	PUNCT
admet-2088	1377	11	w.s	w.s	PROPN
admet-2088	1377	12	.	.	PROPN
admet-2088	1377	13	al	al	PROPN
admet-2088	1377	14	-	-	PUNCT
admet-2088	1377	15	arjan	arjan	PROPN
admet-2088	1377	16	,	,	PUNCT
admet-2088	1377	17	s.i.a	s.i.a	NOUN
admet-2088	1377	18	.	.	PUNCT
admet-2088	1377	19	razak	razak	PROPN
admet-2088	1377	20	,	,	PUNCT
admet-2088	1377	21	a.	a.	PROPN
admet-2088	1377	22	javed	javed	PROPN
admet-2088	1377	23	,	,	PUNCT
admet-2088	1377	24	md.r.a	md.r.a	PROPN
admet-2088	1377	25	.	.	PUNCT
admet-2088	1378	1	kadir	kadir	PROPN
admet-2088	1378	2	.	.	PUNCT
admet-2088	1379	1	nanocomposite	nanocomposite	PROPN
admet-2088	1379	2	hydrogels	hydrogel	NOUN
admet-2088	1379	3	for	for	ADP
admet-2088	1379	4	melanoma	melanoma	NOUN
admet-2088	1379	5	skin	skin	NOUN
admet-2088	1379	6	cancer	cancer	NOUN
admet-2088	1379	7	care	care	NOUN
admet-2088	1379	8	and	and	CCONJ
admet-2088	1379	9	treatment	treatment	NOUN
admet-2088	1379	10	:	:	PUNCT
admet-2088	1379	11	in	in	ADP
admet-2088	1379	12	-	-	PUNCT
admet-2088	1379	13	vitro	vitro	X
admet-2088	1379	14	drug	drug	NOUN
admet-2088	1379	15	delivery	delivery	NOUN
admet-2088	1379	16	,	,	PUNCT
admet-2088	1379	17	drug	drug	NOUN
admet-2088	1379	18	release	release	NOUN
admet-2088	1379	19	kinetics	kinetic	NOUN
admet-2088	1379	20	and	and	CCONJ
admet-2088	1379	21	anti	anti	ADJ
admet-2088	1379	22	-	-	ADJ
admet-2088	1379	23	cancer	cancer	ADJ
admet-2088	1379	24	activities	activity	NOUN
admet-2088	1379	25	.	.	PUNCT
admet-2088	1380	1	arabian	arabian	ADJ
admet-2088	1380	2	journal	journal	PROPN
admet-2088	1380	3	of	of	ADP
admet-2088	1380	4	chemistry	chemistry	NOUN
admet-2088	1380	5	14	14	NUM
admet-2088	1380	6	(	(	PUNCT
admet-2088	1380	7	2021	2021	NUM
admet-2088	1380	8	)	)	PUNCT
admet-2088	1380	9	103120	103120	NUM
admet-2088	1380	10	.	.	PUNCT
admet-2088	1381	1	https://doi.org/10.1016/j.arabjc.2021.103120	https://doi.org/10.1016/j.arabjc.2021.103120	ADJ
admet-2088	1381	2	.	.	PUNCT
admet-2088	1382	1	[	[	X
admet-2088	1382	2	168	168	NUM
admet-2088	1382	3	]	]	PUNCT
admet-2088	1382	4	x.	x.	NOUN
admet-2088	1382	5	zhan	zhan	PROPN
admet-2088	1382	6	,	,	PUNCT
admet-2088	1382	7	w.	w.	PROPN
admet-2088	1382	8	teng	teng	PROPN
admet-2088	1382	9	,	,	PUNCT
admet-2088	1382	10	k.	k.	PROPN
admet-2088	1382	11	sun	sun	PROPN
admet-2088	1382	12	,	,	PUNCT
admet-2088	1382	13	j.	j.	PROPN
admet-2088	1382	14	he	he	PROPN
admet-2088	1382	15	,	,	PUNCT
admet-2088	1382	16	j.	j.	PROPN
admet-2088	1382	17	yang	yang	PROPN
admet-2088	1382	18	,	,	PUNCT
admet-2088	1382	19	j.	j.	PROPN
admet-2088	1382	20	tian	tian	PROPN
admet-2088	1382	21	,	,	PUNCT
admet-2088	1382	22	x.	x.	PROPN
admet-2088	1382	23	huang	huang	PROPN
admet-2088	1382	24	,	,	PUNCT
admet-2088	1382	25	l.	l.	PROPN
admet-2088	1382	26	zhou	zhou	PROPN
admet-2088	1382	27	,	,	PUNCT
admet-2088	1382	28	c.	c.	PROPN
admet-2088	1382	29	zhou	zhou	PROPN
admet-2088	1382	30	.	.	PUNCT
admet-2088	1383	1	cd47	cd47	PROPN
admet-2088	1383	2	-	-	PUNCT
admet-2088	1383	3	mediated	mediate	VERB
admet-2088	1383	4	dticloaded	dticloade	VERB
admet-2088	1383	5	chitosan	chitosan	ADJ
admet-2088	1383	6	oligosaccharide	oligosaccharide	NOUN
admet-2088	1383	7	-	-	PUNCT
admet-2088	1383	8	grafted	graft	VERB
admet-2088	1383	9	ngo	ngo	NOUN
admet-2088	1383	10	for	for	ADP
admet-2088	1383	11	synergistic	synergistic	ADJ
admet-2088	1383	12	chemo	chemo	NOUN
admet-2088	1383	13	-	-	PUNCT
admet-2088	1383	14	photothermal	photothermal	ADJ
admet-2088	1383	15	therapy	therapy	NOUN
admet-2088	1383	16	against	against	ADP
admet-2088	1383	17	malignant	malignant	ADJ
admet-2088	1383	18	melanoma	melanoma	NOUN
admet-2088	1383	19	.	.	PUNCT
admet-2088	1384	1	materials	material	NOUN
admet-2088	1384	2	science	science	NOUN
admet-2088	1384	3	&	&	CCONJ
admet-2088	1384	4	engineering	engineering	PROPN
admet-2088	1384	5	c	c	PROPN
admet-2088	1384	6	123	123	NUM
admet-2088	1384	7	(	(	PUNCT
admet-2088	1384	8	2021	2021	NUM
admet-2088	1384	9	)	)	PUNCT
admet-2088	1384	10	112014	112014	NUM
admet-2088	1384	11	.	.	PUNCT
admet-2088	1385	1	https://doi.org/10.1016/j.msec.2021.112014	https://doi.org/10.1016/j.msec.2021.112014	PROPN
admet-2088	1385	2	.	.	PUNCT
admet-2088	1386	1	[	[	X
admet-2088	1386	2	169	169	NUM
admet-2088	1386	3	]	]	X
admet-2088	1386	4	m.	m.	NOUN
admet-2088	1386	5	bamburowicz	bamburowicz	NOUN
admet-2088	1386	6	-	-	PUNCT
admet-2088	1386	7	klimkowska	klimkowska	PROPN
admet-2088	1386	8	,	,	PUNCT
admet-2088	1386	9	m.	m.	NOUN
admet-2088	1386	10	malecki	malecki	PROPN
admet-2088	1386	11	,	,	PUNCT
admet-2088	1386	12	m.	m.	NOUN
admet-2088	1386	13	bystrzejewski	bystrzejewski	NOUN
admet-2088	1386	14	,	,	PUNCT
admet-2088	1386	15	a.	a.	NOUN
admet-2088	1386	16	kasprzak	kasprzak	PROPN
admet-2088	1386	17	,	,	PUNCT
admet-2088	1386	18	i.p	i.p	PROPN
admet-2088	1386	19	.	.	PROPN
admet-2088	1386	20	grudzinski	grudzinski	PROPN
admet-2088	1386	21	.	.	PUNCT
admet-2088	1387	1	grapheneencapsulated	grapheneencapsulate	VERB
admet-2088	1387	2	iron	iron	NOUN
admet-2088	1387	3	nanoparticles	nanoparticle	NOUN
admet-2088	1387	4	as	as	ADP
admet-2088	1387	5	a	a	DET
admet-2088	1387	6	non	non	ADJ
admet-2088	1387	7	-	-	ADJ
admet-2088	1387	8	viral	viral	ADJ
admet-2088	1387	9	vector	vector	NOUN
admet-2088	1387	10	for	for	ADP
admet-2088	1387	11	gene	gene	NOUN
admet-2088	1387	12	delivery	delivery	NOUN
admet-2088	1387	13	into	into	ADP
admet-2088	1387	14	melanoma	melanoma	NOUN
admet-2088	1387	15	cells	cell	NOUN
admet-2088	1387	16	.	.	PUNCT
admet-2088	1388	1	biochemical	biochemical	ADJ
admet-2088	1388	2	and	and	CCONJ
admet-2088	1388	3	biophysical	biophysical	ADJ
admet-2088	1388	4	research	research	NOUN
admet-2088	1388	5	communications	communication	NOUN
admet-2088	1388	6	652	652	NUM
admet-2088	1388	7	(	(	PUNCT
admet-2088	1388	8	2023	2023	NUM
admet-2088	1388	9	)	)	PUNCT
admet-2088	1388	10	84	84	NUM
admet-2088	1388	11	-	-	SYM
admet-2088	1388	12	87	87	NUM
admet-2088	1388	13	.	.	PUNCT
admet-2088	1388	14	https://doi.org/10.1016/j.bbrc.2023.02.042	https://doi.org/10.1016/j.bbrc.2023.02.042	NOUN
admet-2088	1388	15	.	.	PUNCT
admet-2088	1389	1	[	[	X
admet-2088	1389	2	170	170	NUM
admet-2088	1389	3	]	]	PUNCT
admet-2088	1389	4	q.	q.	PROPN
admet-2088	1389	5	guo	guo	PROPN
admet-2088	1389	6	,	,	PUNCT
admet-2088	1389	7	l.	l.	PROPN
admet-2088	1389	8	li	li	PROPN
admet-2088	1389	9	,	,	PUNCT
admet-2088	1389	10	g.	g.	PROPN
admet-2088	1389	11	guo	guo	PROPN
admet-2088	1389	12	,	,	PUNCT
admet-2088	1389	13	r.	r.	PROPN
admet-2088	1389	14	liu	liu	PROPN
admet-2088	1389	15	,	,	PUNCT
admet-2088	1389	16	y.	y.	PROPN
admet-2088	1389	17	einaga	einaga	PROPN
admet-2088	1389	18	,	,	PUNCT
admet-2088	1389	19	j	j	PROPN
admet-2088	1389	20	zhi	zhi	PROPN
admet-2088	1389	21	.	.	PUNCT
admet-2088	1389	22	nanodiamonds	nanodiamond	NOUN
admet-2088	1389	23	inhibit	inhibit	VERB
admet-2088	1389	24	cancer	cancer	NOUN
admet-2088	1389	25	cell	cell	NOUN
admet-2088	1389	26	migration	migration	NOUN
admet-2088	1389	27	by	by	ADP
admet-2088	1389	28	strengthening	strengthen	VERB
admet-2088	1389	29	cell	cell	NOUN
admet-2088	1389	30	adhesion	adhesion	NOUN
admet-2088	1389	31	:	:	PUNCT
admet-2088	1389	32	implications	implication	NOUN
admet-2088	1389	33	for	for	ADP
admet-2088	1389	34	cancer	cancer	NOUN
admet-2088	1389	35	treatment	treatment	NOUN
admet-2088	1389	36	.	.	PUNCT
admet-2088	1390	1	acs	acs	PROPN
admet-2088	1390	2	applied	apply	VERB
admet-2088	1390	3	materials	material	NOUN
admet-2088	1390	4	&	&	CCONJ
admet-2088	1390	5	interfaces	interface	NOUN
admet-2088	1390	6	13	13	NUM
admet-2088	1390	7	(	(	PUNCT
admet-2088	1390	8	2021	2021	NUM
admet-2088	1390	9	)	)	PUNCT
admet-2088	1390	10	9620	9620	NUM
admet-2088	1390	11	-	-	SYM
admet-2088	1390	12	9629	9629	NUM
admet-2088	1390	13	.	.	PUNCT
admet-2088	1391	1	https://doi.org/10.1021/acsami.0c21332	https://doi.org/10.1021/acsami.0c21332	NOUN
admet-2088	1391	2	.	.	PUNCT
admet-2088	1392	1	[	[	X
admet-2088	1392	2	171	171	NUM
admet-2088	1392	3	]	]	X
admet-2088	1392	4	j.	j.	PROPN
admet-2088	1392	5	nicolas	nicolas	PROPN
admet-2088	1392	6	,	,	PUNCT
admet-2088	1392	7	s.	s.	PROPN
admet-2088	1392	8	mura	mura	PROPN
admet-2088	1392	9	,	,	PUNCT
admet-2088	1392	10	d.	d.	PROPN
admet-2088	1392	11	brambilla	brambilla	PROPN
admet-2088	1392	12	,	,	PUNCT
admet-2088	1392	13	n.	n.	NOUN
admet-2088	1392	14	mackiewicz	mackiewicz	NOUN
admet-2088	1392	15	,	,	PUNCT
admet-2088	1392	16	p.	p.	PROPN
admet-2088	1392	17	couvreur	couvreur	PROPN
admet-2088	1392	18	.	.	PUNCT
admet-2088	1393	1	design	design	NOUN
admet-2088	1393	2	,	,	PUNCT
admet-2088	1393	3	functionalization	functionalization	NOUN
admet-2088	1393	4	strategies	strategy	NOUN
admet-2088	1393	5	and	and	CCONJ
admet-2088	1393	6	biomedical	biomedical	ADJ
admet-2088	1393	7	applications	application	NOUN
admet-2088	1393	8	of	of	ADP
admet-2088	1393	9	targeted	target	VERB
admet-2088	1393	10	biodegradable	biodegradable	ADJ
admet-2088	1393	11	/	/	SYM
admet-2088	1393	12	biocompatible	biocompatible	ADJ
admet-2088	1393	13	polymer	polymer	NOUN
admet-2088	1393	14	-	-	PUNCT
admet-2088	1393	15	based	base	VERB
admet-2088	1393	16	nanocarriers	nanocarrier	NOUN
admet-2088	1393	17	for	for	ADP
admet-2088	1393	18	drug	drug	NOUN
admet-2088	1393	19	delivery	delivery	NOUN
admet-2088	1393	20	.	.	PUNCT
admet-2088	1394	1	chemical	chemical	ADJ
admet-2088	1394	2	society	society	PROPN
admet-2088	1394	3	reviews	review	VERB
admet-2088	1394	4	42	42	NUM
admet-2088	1394	5	(	(	PUNCT
admet-2088	1394	6	2013	2013	NUM
admet-2088	1394	7	)	)	PUNCT
admet-2088	1394	8	1147	1147	NUM
admet-2088	1394	9	-	-	SYM
admet-2088	1394	10	1235	1235	NUM
admet-2088	1394	11	.	.	PUNCT
admet-2088	1395	1	https://doi.org/10.1039/c2cs35265f	https://doi.org/10.1039/c2cs35265f	PROPN
admet-2088	1395	2	.	.	PUNCT
admet-2088	1396	1	[	[	X
admet-2088	1396	2	172	172	NUM
admet-2088	1396	3	]	]	X
admet-2088	1396	4	n.	n.	PROPN
admet-2088	1396	5	deirram	deirram	PROPN
admet-2088	1396	6	,	,	PUNCT
admet-2088	1396	7	c.	c.	PROPN
admet-2088	1396	8	zhang	zhang	PROPN
admet-2088	1396	9	,	,	PUNCT
admet-2088	1396	10	s.s	s.s	PROPN
admet-2088	1396	11	.	.	PROPN
admet-2088	1396	12	kermaniyan	kermaniyan	PROPN
admet-2088	1396	13	,	,	PUNCT
admet-2088	1396	14	a.p.r	a.p.r	ADJ
admet-2088	1396	15	.	.	PUNCT
admet-2088	1397	1	johnston	johnston	PROPN
admet-2088	1397	2	,	,	PUNCT
admet-2088	1397	3	g.k	g.k	PROPN
admet-2088	1397	4	.	.	PROPN
admet-2088	1397	5	such	such	ADJ
admet-2088	1397	6	.	.	PUNCT
admet-2088	1398	1	ph	ph	ADJ
admet-2088	1398	2	-	-	PUNCT
admet-2088	1398	3	responsive	responsive	ADJ
admet-2088	1398	4	polymer	polymer	NOUN
admet-2088	1398	5	nanoparticles	nanoparticle	NOUN
admet-2088	1398	6	for	for	ADP
admet-2088	1398	7	drug	drug	NOUN
admet-2088	1398	8	delivery	delivery	NOUN
admet-2088	1398	9	.	.	PUNCT
admet-2088	1399	1	macromolecular	macromolecular	PROPN
admet-2088	1399	2	rapid	rapid	ADJ
admet-2088	1399	3	communications	communication	NOUN
admet-2088	1399	4	40	40	NUM
admet-2088	1399	5	(	(	PUNCT
admet-2088	1399	6	2019	2019	NUM
admet-2088	1399	7	)	)	PUNCT
admet-2088	1399	8	1800917	1800917	NUM
admet-2088	1399	9	.	.	PUNCT
admet-2088	1400	1	https://doi.org/10.1002/marc.201800917	https://doi.org/10.1002/marc.201800917	NOUN
admet-2088	1400	2	.	.	PUNCT
admet-2088	1401	1	https://doi.org/10.1016/j.jconrel.2018.07.034	https://doi.org/10.1016/j.jconrel.2018.07.034	NOUN
admet-2088	1401	2	https://doi.org/10.1016/j.addr.2016.05.013	https://doi.org/10.1016/j.addr.2016.05.013	PROPN
admet-2088	1401	3	https://doi.org/10.1021/ja01539a017	https://doi.org/10.1021/ja01539a017	PROPN
admet-2088	1401	4	https://doi.org/10.1002/pssb.201200059	https://doi.org/10.1002/pssb.201200059	NOUN
admet-2088	1401	5	https://doi.org/10.1039/c5nr00438a	https://doi.org/10.1039/c5nr00438a	PROPN
admet-2088	1401	6	https://doi.org/10.1016/j.ejpb.2016.04.015	https://doi.org/10.1016/j.ejpb.2016.04.015	NOUN
admet-2088	1401	7	https://doi.org/10.1039/c6ra04349f	https://doi.org/10.1039/c6ra04349f	NOUN
admet-2088	1401	8	https://doi.org/10.1002/adfm.201202460	https://doi.org/10.1002/adfm.201202460	VERB
admet-2088	1401	9	https://doi.org/10.1016/j.elspec.2014.07.003	https://doi.org/10.1016/j.elspec.2014.07.003	NOUN
admet-2088	1401	10	https://doi.org/10.35840/2631-5084/5508	https://doi.org/10.35840/2631-5084/5508	NOUN
admet-2088	1401	11	https://doi.org/10.1016/j.arabjc.2021.103120	https://doi.org/10.1016/j.arabjc.2021.103120	ADJ
admet-2088	1401	12	https://doi.org/10.1016/j.msec.2021.112014	https://doi.org/10.1016/j.msec.2021.112014	PROPN
admet-2088	1401	13	https://doi.org/10.1016/j.bbrc.2023.02.042	https://doi.org/10.1016/j.bbrc.2023.02.042	NOUN
admet-2088	1401	14	https://doi.org/10.1021/acsami.0c21332	https://doi.org/10.1021/acsami.0c21332	NOUN
admet-2088	1401	15	https://doi.org/10.1039/c2cs35265f	https://doi.org/10.1039/c2cs35265f	PROPN
admet-2088	1401	16	https://doi.org/10.1002/marc.201800917	https://doi.org/10.1002/marc.201800917	NOUN
admet-2088	1401	17	admet	admet	PROPN
admet-2088	1401	18	&	&	CCONJ
admet-2088	1401	19	dmpk	dmpk	PROPN
admet-2088	1401	20	12(1	12(1	PROPN
admet-2088	1401	21	)	)	PUNCT
admet-2088	1401	22	(	(	PUNCT
admet-2088	1401	23	2024	2024	NUM
admet-2088	1401	24	)	)	PUNCT
admet-2088	1401	25	107	107	NUM
admet-2088	1401	26	-	-	SYM
admet-2088	1401	27	150	150	NUM
admet-2088	1401	28	nanomaterial	nanomaterial	NOUN
admet-2088	1401	29	-	-	PUNCT
admet-2088	1401	30	based	base	VERB
admet-2088	1401	31	drug	drug	NOUN
admet-2088	1401	32	delivery	delivery	NOUN
admet-2088	1401	33	systems	system	NOUN
admet-2088	1401	34	for	for	ADP
admet-2088	1401	35	melanoma	melanoma	NOUN
admet-2088	1401	36	therapy	therapy	NOUN
admet-2088	1401	37	doi	doi	NOUN
admet-2088	1401	38	:	:	PUNCT
admet-2088	1401	39	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	1401	40	147	147	NUM
admet-2088	1402	1	[	[	X
admet-2088	1402	2	173	173	NUM
admet-2088	1402	3	]	]	X
admet-2088	1402	4	y.	y.	PROPN
admet-2088	1402	5	lee	lee	PROPN
admet-2088	1402	6	,	,	PUNCT
admet-2088	1402	7	d.	d.	PROPN
admet-2088	1402	8	thompson	thompson	PROPN
admet-2088	1402	9	.	.	PUNCT
admet-2088	1403	1	stimuli	stimuli	VERB
admet-2088	1403	2	-	-	PUNCT
admet-2088	1403	3	responsive	responsive	ADJ
admet-2088	1403	4	liposomes	liposome	NOUN
admet-2088	1403	5	for	for	ADP
admet-2088	1403	6	drug	drug	NOUN
admet-2088	1403	7	delivery	delivery	NOUN
admet-2088	1403	8	.	.	PUNCT
admet-2088	1404	1	wiley	wiley	PROPN
admet-2088	1404	2	interdisciplinary	interdisciplinary	ADJ
admet-2088	1404	3	reviews	review	NOUN
admet-2088	1404	4	:	:	PUNCT
admet-2088	1404	5	nanomedicine	nanomedicine	NOUN
admet-2088	1404	6	and	and	CCONJ
admet-2088	1404	7	nanobiotechnology	nanobiotechnology	NOUN
admet-2088	1404	8	9	9	NUM
admet-2088	1404	9	(	(	PUNCT
admet-2088	1404	10	2017	2017	NUM
admet-2088	1404	11	)	)	PUNCT
admet-2088	1404	12	e1450	e1450	NOUN
admet-2088	1404	13	.	.	PUNCT
admet-2088	1405	1	https://doi.org/10.1002/wnan.1450	https://doi.org/10.1002/wnan.1450	NOUN
admet-2088	1405	2	.	.	PUNCT
admet-2088	1406	1	[	[	X
admet-2088	1406	2	174	174	NUM
admet-2088	1406	3	]	]	PUNCT
admet-2088	1406	4	c.-m.j	c.-m.j	PROPN
admet-2088	1406	5	.	.	PUNCT
admet-2088	1406	6	hu	hu	PROPN
admet-2088	1406	7	,	,	PUNCT
admet-2088	1406	8	r.h	r.h	PROPN
admet-2088	1406	9	.	.	PROPN
admet-2088	1406	10	fang	fang	PROPN
admet-2088	1406	11	,	,	PUNCT
admet-2088	1406	12	b.t	b.t	PROPN
admet-2088	1406	13	.	.	PROPN
admet-2088	1406	14	luk	luk	PROPN
admet-2088	1406	15	,	,	PUNCT
admet-2088	1406	16	l.	l.	PROPN
admet-2088	1406	17	zhang	zhang	PROPN
admet-2088	1406	18	.	.	PUNCT
admet-2088	1407	1	polymeric	polymeric	ADJ
admet-2088	1407	2	nanotherapeutics	nanotherapeutic	NOUN
admet-2088	1407	3	:	:	PUNCT
admet-2088	1407	4	clinical	clinical	ADJ
admet-2088	1407	5	development	development	NOUN
admet-2088	1407	6	and	and	CCONJ
admet-2088	1407	7	advances	advance	NOUN
admet-2088	1407	8	in	in	ADP
admet-2088	1407	9	stealth	stealth	ADJ
admet-2088	1407	10	functionalization	functionalization	NOUN
admet-2088	1407	11	strategies	strategy	NOUN
admet-2088	1407	12	.	.	PUNCT
admet-2088	1408	1	nanoscale	nanoscale	NOUN
admet-2088	1408	2	6	6	NUM
admet-2088	1408	3	(	(	PUNCT
admet-2088	1408	4	2014	2014	NUM
admet-2088	1408	5	)	)	PUNCT
admet-2088	1408	6	65	65	NUM
admet-2088	1408	7	-	-	SYM
admet-2088	1408	8	75	75	NUM
admet-2088	1408	9	.	.	PUNCT
admet-2088	1409	1	https://doi.org/10.1039/c3nr05444f	https://doi.org/10.1039/c3nr05444f	X
admet-2088	1409	2	.	.	PUNCT
admet-2088	1410	1	[	[	X
admet-2088	1410	2	175	175	NUM
admet-2088	1410	3	]	]	X
admet-2088	1410	4	s.	s.	PROPN
admet-2088	1410	5	kaur	kaur	PROPN
admet-2088	1410	6	,	,	PUNCT
admet-2088	1410	7	c.	c.	PROPN
admet-2088	1410	8	prasad	prasad	PROPN
admet-2088	1410	9	,	,	PUNCT
admet-2088	1410	10	b.	b.	PROPN
admet-2088	1410	11	balakrishnan	balakrishnan	PROPN
admet-2088	1410	12	,	,	PUNCT
admet-2088	1410	13	r.	r.	PROPN
admet-2088	1410	14	banerjee	banerjee	PROPN
admet-2088	1410	15	.	.	PUNCT
admet-2088	1411	1	trigger	trigger	VERB
admet-2088	1411	2	responsive	responsive	ADJ
admet-2088	1411	3	polymeric	polymeric	ADJ
admet-2088	1411	4	nanocarriers	nanocarrier	NOUN
admet-2088	1411	5	for	for	ADP
admet-2088	1411	6	cancer	cancer	NOUN
admet-2088	1411	7	therapy	therapy	NOUN
admet-2088	1411	8	.	.	PUNCT
admet-2088	1412	1	biomaterial	biomaterial	ADJ
admet-2088	1412	2	science	science	NOUN
admet-2088	1412	3	3	3	NUM
admet-2088	1412	4	(	(	PUNCT
admet-2088	1412	5	2015	2015	NUM
admet-2088	1412	6	)	)	PUNCT
admet-2088	1412	7	955	955	NUM
admet-2088	1412	8	-	-	SYM
admet-2088	1412	9	987	987	NUM
admet-2088	1412	10	.	.	PUNCT
admet-2088	1413	1	https://doi.org/10.1039/c5bm00002e	https://doi.org/10.1039/c5bm00002e	NOUN
admet-2088	1413	2	.	.	PUNCT
admet-2088	1414	1	[	[	X
admet-2088	1414	2	176	176	X
admet-2088	1414	3	]	]	X
admet-2088	1414	4	v.k	v.k	PROPN
admet-2088	1414	5	.	.	PROPN
admet-2088	1414	6	patel	patel	PROPN
admet-2088	1414	7	,	,	PUNCT
admet-2088	1414	8	r.	r.	PROPN
admet-2088	1414	9	srivastava	srivastava	PROPN
admet-2088	1414	10	,	,	PUNCT
admet-2088	1414	11	a.	a.	PROPN
admet-2088	1414	12	sharma	sharma	PROPN
admet-2088	1414	13	,	,	PUNCT
admet-2088	1414	14	a.k	a.k	PROPN
admet-2088	1414	15	.	.	PROPN
admet-2088	1414	16	srivastava	srivastava	PROPN
admet-2088	1414	17	,	,	PUNCT
admet-2088	1414	18	s.	s.	PROPN
admet-2088	1414	19	singh	singh	PROPN
admet-2088	1414	20	,	,	PUNCT
admet-2088	1414	21	a.k	a.k	PROPN
admet-2088	1414	22	.	.	PROPN
admet-2088	1414	23	srivastava	srivastava	PROPN
admet-2088	1414	24	,	,	PUNCT
admet-2088	1414	25	p.l	p.l	PROPN
admet-2088	1414	26	.	.	PROPN
admet-2088	1414	27	kashyap	kashyap	PROPN
admet-2088	1414	28	,	,	PUNCT
admet-2088	1414	29	h.	h.	PROPN
admet-2088	1414	30	chakdar	chakdar	PROPN
admet-2088	1414	31	,	,	PUNCT
admet-2088	1414	32	k.	k.	PROPN
admet-2088	1414	33	pandiyan	pandiyan	PROPN
admet-2088	1414	34	,	,	PUNCT
admet-2088	1414	35	a.	a.	NOUN
admet-2088	1414	36	kalra	kalra	PROPN
admet-2088	1414	37	,	,	PUNCT
admet-2088	1414	38	a.k	a.k	PROPN
admet-2088	1414	39	.	.	PROPN
admet-2088	1414	40	saxena	saxena	PROPN
admet-2088	1414	41	.	.	PUNCT
admet-2088	1415	1	halotolerant	halotolerant	PROPN
admet-2088	1415	2	exiguobacterium	exiguobacterium	PROPN
admet-2088	1415	3	profundum	profundum	PROPN
admet-2088	1415	4	phm11	phm11	PROPN
admet-2088	1415	5	tolerate	tolerate	VERB
admet-2088	1415	6	salinity	salinity	NOUN
admet-2088	1415	7	by	by	ADP
admet-2088	1415	8	accumulating	accumulate	VERB
admet-2088	1415	9	l	l	NOUN
admet-2088	1415	10	-	-	NOUN
admet-2088	1415	11	proline	proline	NOUN
admet-2088	1415	12	and	and	CCONJ
admet-2088	1415	13	finetuning	finetune	VERB
admet-2088	1415	14	gene	gene	NOUN
admet-2088	1415	15	expression	expression	NOUN
admet-2088	1415	16	profiles	profile	NOUN
admet-2088	1415	17	of	of	ADP
admet-2088	1415	18	related	related	ADJ
admet-2088	1415	19	metabolic	metabolic	NOUN
admet-2088	1415	20	pathways	pathway	NOUN
admet-2088	1415	21	.	.	PUNCT
admet-2088	1416	1	frontiers	frontier	NOUN
admet-2088	1416	2	in	in	ADP
admet-2088	1416	3	microbiology	microbiology	NOUN
admet-2088	1416	4	9	9	NUM
admet-2088	1416	5	(	(	PUNCT
admet-2088	1416	6	2018	2018	NUM
admet-2088	1416	7	)	)	PUNCT
admet-2088	1416	8	1	1	NUM
admet-2088	1416	9	-	-	SYM
admet-2088	1416	10	14	14	NUM
admet-2088	1416	11	.	.	PUNCT
admet-2088	1417	1	https://doi.org/10.3389/fmicb.2018.00423	https://doi.org/10.3389/fmicb.2018.00423	PROPN
admet-2088	1417	2	.	.	PUNCT
admet-2088	1418	1	[	[	X
admet-2088	1418	2	177	177	NUM
admet-2088	1418	3	]	]	X
admet-2088	1418	4	n.h	n.h	PROPN
admet-2088	1418	5	.	.	PUNCT
admet-2088	1418	6	abd	abd	PROPN
admet-2088	1418	7	ellah	ellah	PROPN
admet-2088	1418	8	,	,	PUNCT
admet-2088	1418	9	s.a	s.a	PROPN
admet-2088	1418	10	.	.	PROPN
admet-2088	1418	11	abouelmagd	abouelmagd	PROPN
admet-2088	1418	12	.	.	PUNCT
admet-2088	1419	1	surface	surface	NOUN
admet-2088	1419	2	functionalization	functionalization	NOUN
admet-2088	1419	3	of	of	ADP
admet-2088	1419	4	polymeric	polymeric	ADJ
admet-2088	1419	5	nanoparticles	nanoparticle	NOUN
admet-2088	1419	6	for	for	ADP
admet-2088	1419	7	tumor	tumor	NOUN
admet-2088	1419	8	drug	drug	NOUN
admet-2088	1419	9	delivery	delivery	NOUN
admet-2088	1419	10	:	:	PUNCT
admet-2088	1419	11	approaches	approach	NOUN
admet-2088	1419	12	and	and	CCONJ
admet-2088	1419	13	challenges	challenge	NOUN
admet-2088	1419	14	.	.	PUNCT
admet-2088	1420	1	expert	expert	ADJ
admet-2088	1420	2	opinion	opinion	NOUN
admet-2088	1420	3	on	on	ADP
admet-2088	1420	4	drug	drug	NOUN
admet-2088	1420	5	delivery	delivery	NOUN
admet-2088	1420	6	14	14	NUM
admet-2088	1420	7	(	(	PUNCT
admet-2088	1420	8	2017	2017	NUM
admet-2088	1420	9	)	)	PUNCT
admet-2088	1420	10	201	201	NUM
admet-2088	1420	11	-	-	SYM
admet-2088	1420	12	214	214	NUM
admet-2088	1420	13	.	.	PUNCT
admet-2088	1421	1	https://doi.org/10.1080/17425247.2016.1213238	https://doi.org/10.1080/17425247.2016.1213238	NOUN
admet-2088	1421	2	.	.	PUNCT
admet-2088	1422	1	[	[	X
admet-2088	1422	2	178	178	NUM
admet-2088	1422	3	]	]	X
admet-2088	1422	4	f.	f.	PROPN
admet-2088	1422	5	danhier	danhier	PROPN
admet-2088	1422	6	,	,	PUNCT
admet-2088	1422	7	e.	e.	PROPN
admet-2088	1422	8	ansorena	ansorena	PROPN
admet-2088	1422	9	,	,	PUNCT
admet-2088	1422	10	j.m	j.m	PROPN
admet-2088	1422	11	.	.	PROPN
admet-2088	1422	12	silva	silva	PROPN
admet-2088	1422	13	,	,	PUNCT
admet-2088	1422	14	r.	r.	PROPN
admet-2088	1422	15	coco	coco	PROPN
admet-2088	1422	16	,	,	PUNCT
admet-2088	1422	17	a.	a.	PROPN
admet-2088	1422	18	le	le	PROPN
admet-2088	1422	19	breton	breton	PROPN
admet-2088	1422	20	,	,	PUNCT
admet-2088	1422	21	v.	v.	ADP
admet-2088	1422	22	préat	préat	NOUN
admet-2088	1422	23	.	.	PUNCT
admet-2088	1423	1	plga	plga	NOUN
admet-2088	1423	2	-	-	PUNCT
admet-2088	1423	3	based	base	VERB
admet-2088	1423	4	nanoparticles	nanoparticle	NOUN
admet-2088	1423	5	:	:	PUNCT
admet-2088	1423	6	an	an	DET
admet-2088	1423	7	overview	overview	NOUN
admet-2088	1423	8	of	of	ADP
admet-2088	1423	9	biomedical	biomedical	ADJ
admet-2088	1423	10	applications	application	NOUN
admet-2088	1423	11	.	.	PUNCT
admet-2088	1424	1	journal	journal	PROPN
admet-2088	1424	2	of	of	ADP
admet-2088	1424	3	controlled	control	VERB
admet-2088	1424	4	release	release	NOUN
admet-2088	1424	5	161	161	NUM
admet-2088	1424	6	(	(	PUNCT
admet-2088	1424	7	2012	2012	NUM
admet-2088	1424	8	)	)	PUNCT
admet-2088	1424	9	505	505	NUM
admet-2088	1424	10	-	-	SYM
admet-2088	1424	11	522	522	NUM
admet-2088	1424	12	.	.	PUNCT
admet-2088	1425	1	https://doi.org/10.1016/j.jconrel.2012.01.043	https://doi.org/10.1016/j.jconrel.2012.01.043	NOUN
admet-2088	1425	2	.	.	PUNCT
admet-2088	1426	1	[	[	X
admet-2088	1426	2	179	179	NUM
admet-2088	1426	3	]	]	PUNCT
admet-2088	1426	4	m.	m.	NOUN
admet-2088	1426	5	cagel	cagel	NOUN
admet-2088	1426	6	,	,	PUNCT
admet-2088	1426	7	e.	e.	PROPN
admet-2088	1426	8	grotz	grotz	PROPN
admet-2088	1426	9	,	,	PUNCT
admet-2088	1426	10	e.	e.	PROPN
admet-2088	1426	11	bernabeu	bernabeu	PROPN
admet-2088	1426	12	,	,	PUNCT
admet-2088	1426	13	m.a	m.a	PROPN
admet-2088	1426	14	.	.	PROPN
admet-2088	1426	15	moretton	moretton	PROPN
admet-2088	1426	16	,	,	PUNCT
admet-2088	1426	17	d.a	d.a	PROPN
admet-2088	1426	18	.	.	PROPN
admet-2088	1426	19	chiappetta	chiappetta	PROPN
admet-2088	1426	20	,	,	PUNCT
admet-2088	1426	21	doxorubicin	doxorubicin	PROPN
admet-2088	1426	22	:	:	PUNCT
admet-2088	1426	23	nanotechnological	nanotechnological	ADJ
admet-2088	1426	24	overviews	overview	NOUN
admet-2088	1426	25	from	from	ADP
admet-2088	1426	26	bench	bench	NOUN
admet-2088	1426	27	to	to	ADP
admet-2088	1426	28	bedside	bedside	NOUN
admet-2088	1426	29	.	.	PUNCT
admet-2088	1427	1	drug	drug	NOUN
admet-2088	1427	2	discovery	discovery	PROPN
admet-2088	1427	3	today	today	NOUN
admet-2088	1427	4	22	22	NUM
admet-2088	1427	5	(	(	PUNCT
admet-2088	1427	6	2017	2017	NUM
admet-2088	1427	7	)	)	PUNCT
admet-2088	1427	8	270	270	NUM
admet-2088	1427	9	-	-	SYM
admet-2088	1427	10	281	281	NUM
admet-2088	1427	11	.	.	PUNCT
admet-2088	1428	1	https://doi.org/10.1016/j.drudis.2016.11.005	https://doi.org/10.1016/j.drudis.2016.11.005	NOUN
admet-2088	1428	2	.	.	PUNCT
admet-2088	1429	1	[	[	X
admet-2088	1429	2	180	180	NUM
admet-2088	1429	3	]	]	PUNCT
admet-2088	1429	4	a.	a.	NOUN
admet-2088	1429	5	zielinska	zielinska	PROPN
admet-2088	1429	6	,	,	PUNCT
admet-2088	1429	7	f.	f.	PROPN
admet-2088	1429	8	carreir	carreir	PROPN
admet-2088	1429	9	,	,	PUNCT
admet-2088	1429	10	a.m.	a.m.	PROPN
admet-2088	1429	11	oliveira	oliveira	PROPN
admet-2088	1429	12	,	,	PUNCT
admet-2088	1429	13	a.	a.	PROPN
admet-2088	1429	14	neves	neves	PROPN
admet-2088	1429	15	,	,	PUNCT
admet-2088	1429	16	b.	b.	PROPN
admet-2088	1429	17	pires	pires	PROPN
admet-2088	1429	18	,	,	PUNCT
admet-2088	1429	19	d.n	d.n	PROPN
admet-2088	1429	20	.	.	PROPN
admet-2088	1429	21	venkatesh	venkatesh	PROPN
admet-2088	1429	22	,	,	PUNCT
admet-2088	1429	23	a.	a.	NOUN
admet-2088	1429	24	durazzo	durazzo	NOUN
admet-2088	1429	25	,	,	PUNCT
admet-2088	1429	26	m.	m.	NOUN
admet-2088	1429	27	lucarini	lucarini	NOUN
admet-2088	1429	28	,	,	PUNCT
admet-2088	1429	29	p.	p.	NOUN
admet-2088	1429	30	eder	eder	NOUN
admet-2088	1429	31	,	,	PUNCT
admet-2088	1429	32	a.m.	a.m.	PROPN
admet-2088	1429	33	silva	silva	PROPN
admet-2088	1429	34	,	,	PUNCT
admet-2088	1429	35	a.	a.	NOUN
admet-2088	1429	36	santini	santini	PROPN
admet-2088	1429	37	,	,	PUNCT
admet-2088	1429	38	e.b	e.b	PROPN
admet-2088	1429	39	.	.	PROPN
admet-2088	1429	40	souto	souto	PROPN
admet-2088	1429	41	.	.	PUNCT
admet-2088	1430	1	polymeric	polymeric	ADJ
admet-2088	1430	2	nanoparticles	nanoparticle	NOUN
admet-2088	1430	3	:	:	PUNCT
admet-2088	1430	4	production	production	NOUN
admet-2088	1430	5	,	,	PUNCT
admet-2088	1430	6	characterization	characterization	NOUN
admet-2088	1430	7	,	,	PUNCT
admet-2088	1430	8	toxicology	toxicology	NOUN
admet-2088	1430	9	and	and	CCONJ
admet-2088	1430	10	ecotoxicology	ecotoxicology	NOUN
admet-2088	1430	11	.	.	PUNCT
admet-2088	1431	1	molecules	molecule	NOUN
admet-2088	1431	2	25	25	NUM
admet-2088	1431	3	(	(	PUNCT
admet-2088	1431	4	2020	2020	NUM
admet-2088	1431	5	)	)	PUNCT
admet-2088	1431	6	.	.	PUNCT
admet-2088	1432	1	https://doi.org/10.3390/molecules25163731	https://doi.org/10.3390/molecules25163731	NOUN
admet-2088	1432	2	.	.	PUNCT
admet-2088	1433	1	[	[	X
admet-2088	1433	2	181	181	NUM
admet-2088	1433	3	]	]	PUNCT
admet-2088	1433	4	a.	a.	NOUN
admet-2088	1433	5	mehandole	mehandole	NOUN
admet-2088	1433	6	,	,	PUNCT
admet-2088	1433	7	n.	n.	PROPN
admet-2088	1433	8	walke	walke	PROPN
admet-2088	1433	9	,	,	PUNCT
admet-2088	1433	10	s.	s.	PROPN
admet-2088	1433	11	mahajan	mahajan	PROPN
admet-2088	1433	12	,	,	PUNCT
admet-2088	1433	13	m.	m.	NOUN
admet-2088	1433	14	aalhate	aalhate	NOUN
admet-2088	1433	15	,	,	PUNCT
admet-2088	1433	16	i.	i.	PROPN
admet-2088	1433	17	maji	maji	PROPN
admet-2088	1433	18	,	,	PUNCT
admet-2088	1433	19	u.	u.	PROPN
admet-2088	1433	20	gupta	gupta	PROPN
admet-2088	1433	21	,	,	PUNCT
admet-2088	1433	22	n.k	n.k	PROPN
admet-2088	1433	23	.	.	PROPN
admet-2088	1433	24	mehra	mehra	PROPN
admet-2088	1433	25	,	,	PUNCT
admet-2088	1433	26	p.k	p.k	PROPN
admet-2088	1433	27	.	.	PROPN
admet-2088	1433	28	singh	singh	PROPN
admet-2088	1433	29	.	.	PUNCT
admet-2088	1434	1	core	core	ADJ
admet-2088	1434	2	-	-	PUNCT
admet-2088	1434	3	shell	shell	NOUN
admet-2088	1434	4	type	type	NOUN
admet-2088	1434	5	lipidic	lipidic	NOUN
admet-2088	1434	6	and	and	CCONJ
admet-2088	1434	7	polymeric	polymeric	ADJ
admet-2088	1434	8	nanocapsules	nanocapsule	NOUN
admet-2088	1434	9	:	:	PUNCT
admet-2088	1434	10	the	the	DET
admet-2088	1434	11	transformative	transformative	ADJ
admet-2088	1434	12	multifaceted	multifaceted	ADJ
admet-2088	1434	13	delivery	delivery	NOUN
admet-2088	1434	14	systems	system	NOUN
admet-2088	1434	15	.	.	PUNCT
admet-2088	1435	1	aaps	aap	NOUN
admet-2088	1435	2	pharmscitech	pharmscitech	VERB
admet-2088	1435	3	24	24	NUM
admet-2088	1435	4	(	(	PUNCT
admet-2088	1435	5	2023	2023	NUM
admet-2088	1435	6	)	)	PUNCT
admet-2088	1435	7	50	50	NUM
admet-2088	1435	8	.	.	PUNCT
admet-2088	1436	1	https://doi.org/10.1208/s12249-023-02504-z	https://doi.org/10.1208/s12249-023-02504-z	NOUN
admet-2088	1436	2	.	.	PUNCT
admet-2088	1437	1	[	[	X
admet-2088	1437	2	182	182	NUM
admet-2088	1437	3	]	]	X
admet-2088	1437	4	a.r	a.r	PROPN
admet-2088	1437	5	.	.	PROPN
admet-2088	1437	6	pohlmann	pohlmann	PROPN
admet-2088	1437	7	,	,	PUNCT
admet-2088	1437	8	c.b	c.b	PROPN
admet-2088	1437	9	.	.	PROPN
admet-2088	1437	10	detoni	detoni	PROPN
admet-2088	1437	11	,	,	PUNCT
admet-2088	1437	12	k.	k.	PROPN
admet-2088	1437	13	paese	paese	PROPN
admet-2088	1437	14	,	,	PUNCT
admet-2088	1437	15	k.	k.	PROPN
admet-2088	1437	16	coradini	coradini	PROPN
admet-2088	1437	17	,	,	PUNCT
admet-2088	1437	18	r.c	r.c	PROPN
admet-2088	1437	19	.	.	PROPN
admet-2088	1437	20	beck	beck	PROPN
admet-2088	1437	21	,	,	PUNCT
admet-2088	1437	22	s.s	s.s	PROPN
admet-2088	1437	23	.	.	PROPN
admet-2088	1437	24	guterres	guterre	NOUN
admet-2088	1437	25	,	,	PUNCT
admet-2088	1437	26	polymeric	polymeric	ADJ
admet-2088	1437	27	nanocapsules	nanocapsule	NOUN
admet-2088	1437	28	for	for	ADP
admet-2088	1437	29	topical	topical	ADJ
admet-2088	1437	30	delivery	delivery	NOUN
admet-2088	1437	31	,	,	PUNCT
admet-2088	1437	32	in	in	ADP
admet-2088	1437	33	n.	n.	PROPN
admet-2088	1437	34	dragicevic	dragicevic	PROPN
admet-2088	1437	35	,	,	PUNCT
admet-2088	1437	36	h.	h.	PROPN
admet-2088	1437	37	maibach	maibach	PROPN
admet-2088	1437	38	(	(	PUNCT
admet-2088	1437	39	eds	eds	PROPN
admet-2088	1437	40	.	.	PUNCT
admet-2088	1437	41	)	)	PUNCT
admet-2088	1437	42	.	.	PUNCT
admet-2088	1437	43	,	,	PUNCT
admet-2088	1437	44	percutaneous	percutaneous	ADJ
admet-2088	1437	45	penetration	penetration	NOUN
admet-2088	1437	46	enhancers	enhancer	VERB
admet-2088	1437	47	chemical	chemical	NOUN
admet-2088	1437	48	methods	method	NOUN
admet-2088	1437	49	in	in	ADP
admet-2088	1437	50	penetration	penetration	NOUN
admet-2088	1437	51	enhancement	enhancement	NOUN
admet-2088	1437	52	:	:	PUNCT
admet-2088	1437	53	nanocarriers	nanocarrier	NOUN
admet-2088	1437	54	,	,	PUNCT
admet-2088	1437	55	springer	springer	NOUN
admet-2088	1437	56	,	,	PUNCT
admet-2088	1437	57	berlin	berlin	PROPN
admet-2088	1437	58	,	,	PUNCT
admet-2088	1437	59	heidelberg	heidelberg	PROPN
admet-2088	1437	60	.	.	PUNCT
admet-2088	1438	1	2016	2016	NUM
admet-2088	1438	2	,	,	PUNCT
admet-2088	1438	3	p.	p.	NOUN
admet-2088	1438	4	201	201	NUM
admet-2088	1438	5	-	-	SYM
admet-2088	1438	6	221	221	NUM
admet-2088	1438	7	.	.	PUNCT
admet-2088	1439	1	https://doi.org/10.1007/978-3-662-47862-2_13	https://doi.org/10.1007/978-3-662-47862-2_13	NOUN
admet-2088	1439	2	.	.	PUNCT
admet-2088	1440	1	[	[	X
admet-2088	1440	2	183	183	NUM
admet-2088	1440	3	]	]	PUNCT
admet-2088	1440	4	r.	r.	PROPN
admet-2088	1440	5	pan	pan	PROPN
admet-2088	1440	6	,	,	PUNCT
admet-2088	1440	7	y.	y.	PROPN
admet-2088	1440	8	zeng	zeng	PROPN
admet-2088	1440	9	,	,	PUNCT
admet-2088	1440	10	g.	g.	PROPN
admet-2088	1440	11	liu	liu	PROPN
admet-2088	1440	12	,	,	PUNCT
admet-2088	1440	13	y.	y.	PROPN
admet-2088	1440	14	wei	wei	PROPN
admet-2088	1440	15	,	,	PUNCT
admet-2088	1440	16	y.	y.	PROPN
admet-2088	1440	17	xu	xu	PROPN
admet-2088	1440	18	,	,	PUNCT
admet-2088	1440	19	l.	l.	PROPN
admet-2088	1440	20	tao	tao	PROPN
admet-2088	1440	21	,	,	PUNCT
admet-2088	1440	22	curcumin	curcumin	NOUN
admet-2088	1440	23	-	-	PUNCT
admet-2088	1440	24	polymer	polymer	NOUN
admet-2088	1440	25	conjugates	conjugate	NOUN
admet-2088	1440	26	with	with	ADP
admet-2088	1440	27	dynamic	dynamic	ADJ
admet-2088	1440	28	boronic	boronic	ADJ
admet-2088	1440	29	acid	acid	NOUN
admet-2088	1440	30	ester	ester	NOUN
admet-2088	1440	31	linkages	linkage	NOUN
admet-2088	1440	32	for	for	ADP
admet-2088	1440	33	selective	selective	ADJ
admet-2088	1440	34	killing	killing	NOUN
admet-2088	1440	35	of	of	ADP
admet-2088	1440	36	cancer	cancer	NOUN
admet-2088	1440	37	cells	cell	NOUN
admet-2088	1440	38	.	.	PUNCT
admet-2088	1441	1	polymer	polymer	NOUN
admet-2088	1441	2	chemistry	chemistry	NOUN
admet-2088	1441	3	11	11	NUM
admet-2088	1441	4	(	(	PUNCT
admet-2088	1441	5	2020	2020	NUM
admet-2088	1441	6	)	)	PUNCT
admet-2088	1441	7	1321	1321	NUM
admet-2088	1441	8	-	-	SYM
admet-2088	1441	9	1326	1326	NUM
admet-2088	1441	10	.	.	PUNCT
admet-2088	1442	1	https://doi.org/10.1039/c9py01596e	https://doi.org/10.1039/c9py01596e	X
admet-2088	1442	2	.	.	PUNCT
admet-2088	1443	1	[	[	X
admet-2088	1443	2	184	184	NUM
admet-2088	1443	3	]	]	X
admet-2088	1443	4	r.	r.	PROPN
admet-2088	1443	5	scopel	scopel	PROPN
admet-2088	1443	6	,	,	PUNCT
admet-2088	1443	7	m.a	m.a	PROPN
admet-2088	1443	8	.	.	PROPN
admet-2088	1443	9	falcão	falcão	PROPN
admet-2088	1443	10	,	,	PUNCT
admet-2088	1443	11	a.r	a.r	PROPN
admet-2088	1443	12	.	.	PROPN
admet-2088	1443	13	cappellari	cappellari	PROPN
admet-2088	1443	14	,	,	PUNCT
admet-2088	1443	15	f.b	f.b	PROPN
admet-2088	1443	16	.	.	PROPN
admet-2088	1443	17	morrone	morrone	PROPN
admet-2088	1443	18	,	,	PUNCT
admet-2088	1443	19	s.s	s.s	PROPN
admet-2088	1443	20	.	.	PROPN
admet-2088	1443	21	guterres	guterre	NOUN
admet-2088	1443	22	,	,	PUNCT
admet-2088	1443	23	e.	e.	PROPN
admet-2088	1443	24	cassel	cassel	PROPN
admet-2088	1443	25	,	,	PUNCT
admet-2088	1443	26	a.m.	a.m.	PROPN
admet-2088	1443	27	kasko	kasko	PROPN
admet-2088	1443	28	,	,	PUNCT
admet-2088	1443	29	r.m.f	r.m.f	ADJ
admet-2088	1443	30	.	.	PUNCT
admet-2088	1443	31	vargas	vargas	NOUN
admet-2088	1443	32	.	.	PUNCT
admet-2088	1444	1	lipid	lipid	NOUN
admet-2088	1444	2	-	-	PUNCT
admet-2088	1444	3	polymer	polymer	NOUN
admet-2088	1444	4	hybrid	hybrid	NOUN
admet-2088	1444	5	nanoparticles	nanoparticle	NOUN
admet-2088	1444	6	as	as	ADP
admet-2088	1444	7	a	a	DET
admet-2088	1444	8	targeted	target	VERB
admet-2088	1444	9	drug	drug	NOUN
admet-2088	1444	10	delivery	delivery	NOUN
admet-2088	1444	11	system	system	NOUN
admet-2088	1444	12	for	for	ADP
admet-2088	1444	13	melanoma	melanoma	NOUN
admet-2088	1444	14	treatment	treatment	NOUN
admet-2088	1444	15	.	.	PUNCT
admet-2088	1445	1	international	international	ADJ
admet-2088	1445	2	journal	journal	NOUN
admet-2088	1445	3	of	of	ADP
admet-2088	1445	4	polymeric	polymeric	ADJ
admet-2088	1445	5	materials	material	NOUN
admet-2088	1445	6	and	and	CCONJ
admet-2088	1445	7	polymeric	polymeric	ADJ
admet-2088	1445	8	biomaterials	biomaterial	NOUN
admet-2088	1445	9	71	71	NUM
admet-2088	1445	10	(	(	PUNCT
admet-2088	1445	11	2022	2022	NUM
admet-2088	1445	12	)	)	PUNCT
admet-2088	1445	13	127138	127138	NUM
admet-2088	1445	14	.	.	PUNCT
admet-2088	1446	1	https://doi.org/10.1080/00914037.2020.1809406	https://doi.org/10.1080/00914037.2020.1809406	PROPN
admet-2088	1446	2	.	.	PUNCT
admet-2088	1447	1	[	[	X
admet-2088	1447	2	185	185	NUM
admet-2088	1447	3	]	]	PUNCT
admet-2088	1447	4	m.	m.	NOUN
admet-2088	1447	5	song	song	NOUN
admet-2088	1447	6	,	,	PUNCT
admet-2088	1447	7	b.	b.	PROPN
admet-2088	1447	8	zhu	zhu	PROPN
admet-2088	1447	9	,	,	PUNCT
admet-2088	1447	10	s.	s.	PROPN
admet-2088	1447	11	qiu	qiu	PROPN
admet-2088	1447	12	,	,	PUNCT
admet-2088	1447	13	j.	j.	PROPN
admet-2088	1447	14	tian	tian	PROPN
admet-2088	1447	15	,	,	PUNCT
admet-2088	1447	16	j.	j.	PROPN
admet-2088	1447	17	li	li	PROPN
admet-2088	1447	18	,	,	PUNCT
admet-2088	1447	19	d.	d.	PROPN
admet-2088	1447	20	chen	chen	PROPN
admet-2088	1447	21	,	,	PUNCT
admet-2088	1447	22	c.	c.	PROPN
admet-2088	1447	23	liu	liu	PROPN
admet-2088	1447	24	.	.	PUNCT
admet-2088	1448	1	codelivery	codelivery	NOUN
admet-2088	1448	2	of	of	ADP
admet-2088	1448	3	afuresertib	afuresertib	NOUN
admet-2088	1448	4	and	and	CCONJ
admet-2088	1448	5	celecoxib	celecoxib	VERB
admet-2088	1448	6	by	by	ADP
admet-2088	1448	7	il4rpep-1	il4rpep-1	ADV
admet-2088	1448	8	-	-	PUNCT
admet-2088	1448	9	targeting	target	VERB
admet-2088	1448	10	nanoparticles	nanoparticle	NOUN
admet-2088	1448	11	for	for	ADP
admet-2088	1448	12	effective	effective	ADJ
admet-2088	1448	13	treatment	treatment	NOUN
admet-2088	1448	14	against	against	ADP
admet-2088	1448	15	melanoma	melanoma	NOUN
admet-2088	1448	16	.	.	PUNCT
admet-2088	1449	1	applied	apply	VERB
admet-2088	1449	2	materials	material	NOUN
admet-2088	1449	3	today	today	NOUN
admet-2088	1449	4	33	33	NUM
admet-2088	1449	5	(	(	PUNCT
admet-2088	1449	6	2023	2023	NUM
admet-2088	1449	7	)	)	PUNCT
admet-2088	1449	8	101868	101868	NUM
admet-2088	1449	9	.	.	PUNCT
admet-2088	1450	1	https://doi.org/10.1016/j.apmt.2023.101868	https://doi.org/10.1016/j.apmt.2023.101868	PROPN
admet-2088	1450	2	.	.	PUNCT
admet-2088	1451	1	[	[	X
admet-2088	1451	2	186	186	NUM
admet-2088	1451	3	]	]	PUNCT
admet-2088	1451	4	b.	b.	PROPN
admet-2088	1451	5	mishra	mishra	PROPN
admet-2088	1451	6	,	,	PUNCT
admet-2088	1451	7	bhavesh	bhavesh	PROPN
admet-2088	1451	8	b.	b.	PROPN
admet-2088	1451	9	patel	patel	PROPN
admet-2088	1451	10	,	,	PUNCT
admet-2088	1451	11	sanjay	sanjay	PROPN
admet-2088	1451	12	tiwari	tiwari	PROPN
admet-2088	1451	13	.	.	PUNCT
admet-2088	1451	14	colloidal	colloidal	NOUN
admet-2088	1451	15	nanocarriers	nanocarrier	NOUN
admet-2088	1451	16	:	:	PUNCT
admet-2088	1451	17	a	a	DET
admet-2088	1451	18	review	review	NOUN
admet-2088	1451	19	on	on	ADP
admet-2088	1451	20	formulation	formulation	NOUN
admet-2088	1451	21	technology	technology	NOUN
admet-2088	1451	22	,	,	PUNCT
admet-2088	1451	23	types	type	NOUN
admet-2088	1451	24	and	and	CCONJ
admet-2088	1451	25	applications	application	NOUN
admet-2088	1451	26	toward	toward	ADP
admet-2088	1451	27	targeted	target	VERB
admet-2088	1451	28	drug	drug	NOUN
admet-2088	1451	29	delivery	delivery	NOUN
admet-2088	1451	30	.	.	PUNCT
admet-2088	1452	1	nanomedicine	nanomedicine	NOUN
admet-2088	1452	2	:	:	PUNCT
admet-2088	1452	3	nanotechnology	nanotechnology	NOUN
admet-2088	1452	4	biology	biology	NOUN
admet-2088	1452	5	and	and	CCONJ
admet-2088	1452	6	medicine	medicine	NOUN
admet-2088	1452	7	6	6	NUM
admet-2088	1452	8	(	(	PUNCT
admet-2088	1452	9	2010	2010	NUM
admet-2088	1452	10	)	)	PUNCT
admet-2088	1452	11	9	9	NUM
admet-2088	1452	12	-	-	SYM
admet-2088	1452	13	24	24	NUM
admet-2088	1452	14	.	.	PUNCT
admet-2088	1453	1	https://doi.org/10.1016/j.nano.2009.04.008	https://doi.org/10.1016/j.nano.2009.04.008	NOUN
admet-2088	1453	2	.	.	PUNCT
admet-2088	1454	1	[	[	X
admet-2088	1454	2	187	187	NUM
admet-2088	1454	3	]	]	X
admet-2088	1454	4	s.r	s.r	PROPN
admet-2088	1454	5	.	.	PROPN
admet-2088	1454	6	mudshinge	mudshinge	PROPN
admet-2088	1454	7	,	,	PUNCT
admet-2088	1454	8	a.b	a.b	PROPN
admet-2088	1454	9	.	.	PROPN
admet-2088	1454	10	deore	deore	PROPN
admet-2088	1454	11	,	,	PUNCT
admet-2088	1454	12	s.	s.	PROPN
admet-2088	1454	13	patil	patil	PROPN
admet-2088	1454	14	,	,	PUNCT
admet-2088	1454	15	c.m	c.m	PROPN
admet-2088	1454	16	.	.	PROPN
admet-2088	1454	17	bhalgat	bhalgat	PROPN
admet-2088	1454	18	.	.	PUNCT
admet-2088	1455	1	nanoparticles	nanoparticle	NOUN
admet-2088	1455	2	:	:	PUNCT
admet-2088	1455	3	emerging	emerge	VERB
admet-2088	1455	4	carriers	carrier	NOUN
admet-2088	1455	5	for	for	ADP
admet-2088	1455	6	drug	drug	NOUN
admet-2088	1455	7	delivery	delivery	NOUN
admet-2088	1455	8	.	.	PUNCT
admet-2088	1456	1	saudi	saudi	ADJ
admet-2088	1456	2	pharmaceutical	pharmaceutical	PROPN
admet-2088	1456	3	journal	journal	PROPN
admet-2088	1456	4	19	19	NUM
admet-2088	1456	5	(	(	PUNCT
admet-2088	1456	6	2011	2011	NUM
admet-2088	1456	7	)	)	PUNCT
admet-2088	1456	8	129	129	NUM
admet-2088	1456	9	-	-	SYM
admet-2088	1456	10	141	141	NUM
admet-2088	1456	11	.	.	PUNCT
admet-2088	1456	12	https://doi.org/10.1016/j.jsps.2011.04.001	https://doi.org/10.1016/j.jsps.2011.04.001	NOUN
admet-2088	1456	13	.	.	PUNCT
admet-2088	1457	1	[	[	X
admet-2088	1457	2	188	188	NUM
admet-2088	1457	3	]	]	PUNCT
admet-2088	1457	4	h.j	h.j	PROPN
admet-2088	1457	5	.	.	PROPN
admet-2088	1457	6	hsu	hsu	PROPN
admet-2088	1457	7	,	,	PUNCT
admet-2088	1457	8	j.	j.	PROPN
admet-2088	1457	9	bugno	bugno	PROPN
admet-2088	1457	10	,	,	PUNCT
admet-2088	1457	11	s.-r	s.-r	PROPN
admet-2088	1457	12	.	.	PUNCT
admet-2088	1458	1	lee	lee	PROPN
admet-2088	1458	2	,	,	PUNCT
admet-2088	1458	3	s.	s.	PROPN
admet-2088	1458	4	hong	hong	PROPN
admet-2088	1458	5	.	.	PUNCT
admet-2088	1459	1	dendrimer	dendrimer	NOUN
admet-2088	1459	2	-	-	PUNCT
admet-2088	1459	3	based	base	VERB
admet-2088	1459	4	nanocarriers	nanocarrier	NOUN
admet-2088	1459	5	:	:	PUNCT
admet-2088	1459	6	a	a	DET
admet-2088	1459	7	versatile	versatile	ADJ
admet-2088	1459	8	platform	platform	NOUN
admet-2088	1459	9	for	for	ADP
admet-2088	1459	10	drug	drug	NOUN
admet-2088	1459	11	delivery	delivery	NOUN
admet-2088	1459	12	.	.	PUNCT
admet-2088	1460	1	wiley	wiley	PROPN
admet-2088	1460	2	interdisciplinary	interdisciplinary	ADJ
admet-2088	1460	3	reviews	review	NOUN
admet-2088	1460	4	-	-	PUNCT
admet-2088	1460	5	nanomedicine	nanomedicine	ADJ
admet-2088	1460	6	and	and	CCONJ
admet-2088	1460	7	nanobiotechnology	nanobiotechnology	NOUN
admet-2088	1460	8	9	9	NUM
admet-2088	1460	9	(	(	PUNCT
admet-2088	1460	10	2017	2017	NUM
admet-2088	1460	11	)	)	PUNCT
admet-2088	1460	12	.	.	PUNCT
admet-2088	1461	1	https://doi.org/10.1002/wnan.1409	https://doi.org/10.1002/wnan.1409	PROPN
admet-2088	1461	2	.	.	PUNCT
admet-2088	1462	1	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	PRON
admet-2088	1463	1	https://doi.org/10.1002/wnan.1450	https://doi.org/10.1002/wnan.1450	ADJ
admet-2088	1463	2	https://doi.org/10.1039/c3nr05444f	https://doi.org/10.1039/c3nr05444f	PROPN
admet-2088	1463	3	https://doi.org/10.1039/c5bm00002e	https://doi.org/10.1039/c5bm00002e	PROPN
admet-2088	1463	4	https://doi.org/10.3389/fmicb.2018.00423	https://doi.org/10.3389/fmicb.2018.00423	PROPN
admet-2088	1463	5	https://doi.org/10.1080/17425247.2016.1213238	https://doi.org/10.1080/17425247.2016.1213238	ADP
admet-2088	1463	6	https://doi.org/10.1016/j.jconrel.2012.01.043	https://doi.org/10.1016/j.jconrel.2012.01.043	NOUN
admet-2088	1463	7	https://doi.org/10.1016/j.drudis.2016.11.005	https://doi.org/10.1016/j.drudis.2016.11.005	PROPN
admet-2088	1463	8	https://doi.org/10.3390/molecules25163731	https://doi.org/10.3390/molecules25163731	NOUN
admet-2088	1463	9	https://doi.org/10.1208/s12249-023-02504-z	https://doi.org/10.1208/s12249-023-02504-z	NOUN
admet-2088	1463	10	https://doi.org/10.1007/978-3-662-47862-2_13	https://doi.org/10.1007/978-3-662-47862-2_13	PUNCT
admet-2088	1463	11	https://doi.org/10.1039/c9py01596e	https://doi.org/10.1039/c9py01596e	PROPN
admet-2088	1463	12	https://doi.org/10.1080/00914037.2020.1809406	https://doi.org/10.1080/00914037.2020.1809406	PROPN
admet-2088	1463	13	https://doi.org/10.1016/j.apmt.2023.101868	https://doi.org/10.1016/j.apmt.2023.101868	VERB
admet-2088	1463	14	https://doi.org/10.1016/j.nano.2009.04.008	https://doi.org/10.1016/j.nano.2009.04.008	PROPN
admet-2088	1463	15	https://doi.org/10.1016/j.jsps.2011.04.001	https://doi.org/10.1016/j.jsps.2011.04.001	PROPN
admet-2088	1463	16	https://doi.org/10.1002/wnan.1409	https://doi.org/10.1002/wnan.1409	NOUN
admet-2088	1463	17	m.	m.	NOUN
admet-2088	1463	18	kulkarni	kulkarni	PROPN
admet-2088	1463	19	et	et	PROPN
admet-2088	1463	20	al	al	PROPN
admet-2088	1463	21	.	.	PROPN
admet-2088	1463	22	admet	admet	PROPN
admet-2088	1463	23	&	&	CCONJ
admet-2088	1463	24	dmpk	dmpk	PROPN
admet-2088	1463	25	12(1	12(1	PROPN
admet-2088	1463	26	)	)	PUNCT
admet-2088	1463	27	(	(	PUNCT
admet-2088	1463	28	2024	2024	NUM
admet-2088	1463	29	)	)	PUNCT
admet-2088	1463	30	107	107	NUM
admet-2088	1463	31	-	-	SYM
admet-2088	1463	32	150	150	NUM
admet-2088	1463	33	148	148	NUM
admet-2088	1463	34	[	[	X
admet-2088	1463	35	189	189	NUM
admet-2088	1463	36	]	]	PUNCT
admet-2088	1463	37	g.	g.	PROPN
admet-2088	1463	38	jiang	jiang	PROPN
admet-2088	1463	39	,	,	PUNCT
admet-2088	1463	40	r.	r.	PROPN
admet-2088	1463	41	li	li	PROPN
admet-2088	1463	42	,	,	PUNCT
admet-2088	1463	43	j.	j.	PROPN
admet-2088	1463	44	tang	tang	PROPN
admet-2088	1463	45	,	,	PUNCT
admet-2088	1463	46	y.	y.	PROPN
admet-2088	1463	47	ma	ma	PROPN
admet-2088	1463	48	,	,	PUNCT
admet-2088	1463	49	x.	x.	PROPN
admet-2088	1463	50	hou	hou	PROPN
admet-2088	1463	51	,	,	PUNCT
admet-2088	1463	52	c.	c.	PROPN
admet-2088	1463	53	yang	yang	PROPN
admet-2088	1463	54	,	,	PUNCT
admet-2088	1463	55	w.	w.	PROPN
admet-2088	1463	56	guo	guo	PROPN
admet-2088	1463	57	,	,	PUNCT
admet-2088	1463	58	y.	y.	PROPN
admet-2088	1463	59	xin	xin	PROPN
admet-2088	1463	60	,	,	PUNCT
admet-2088	1463	61	y.	y.	PROPN
admet-2088	1463	62	liu	liu	PROPN
admet-2088	1463	63	.	.	PUNCT
admet-2088	1464	1	formulation	formulation	NOUN
admet-2088	1464	2	of	of	ADP
admet-2088	1464	3	temozolomideloaded	temozolomideloade	VERB
admet-2088	1464	4	nanoparticles	nanoparticle	NOUN
admet-2088	1464	5	and	and	CCONJ
admet-2088	1464	6	their	their	PRON
admet-2088	1464	7	targeting	target	VERB
admet-2088	1464	8	potential	potential	NOUN
admet-2088	1464	9	to	to	ADP
admet-2088	1464	10	melanoma	melanoma	NOUN
admet-2088	1464	11	cells	cell	NOUN
admet-2088	1464	12	.	.	PUNCT
admet-2088	1465	1	oncology	oncology	NOUN
admet-2088	1465	2	reports	report	VERB
admet-2088	1465	3	37	37	NUM
admet-2088	1465	4	(	(	PUNCT
admet-2088	1465	5	2017	2017	NUM
admet-2088	1465	6	)	)	PUNCT
admet-2088	1465	7	995	995	NUM
admet-2088	1465	8	-	-	SYM
admet-2088	1465	9	1001	1001	NUM
admet-2088	1465	10	.	.	PUNCT
admet-2088	1466	1	https://doi.org/10.3892/or.2016.5342	https://doi.org/10.3892/or.2016.5342	NOUN
admet-2088	1466	2	.	.	PUNCT
admet-2088	1467	1	[	[	X
admet-2088	1467	2	190	190	NUM
admet-2088	1467	3	]	]	X
admet-2088	1467	4	c.-c	c.-c	NOUN
admet-2088	1467	5	.	.	PUNCT
admet-2088	1468	1	cheng	cheng	PROPN
admet-2088	1468	2	,	,	PUNCT
admet-2088	1468	3	f.-c	f.-c	PROPN
admet-2088	1468	4	.	.	PUNCT
admet-2088	1469	1	chang	chang	PROPN
admet-2088	1469	2	,	,	PUNCT
admet-2088	1469	3	w.-y	w.-y	NOUN
admet-2088	1469	4	.	.	PUNCT
admet-2088	1470	1	kao	kao	PROPN
admet-2088	1470	2	,	,	PUNCT
admet-2088	1470	3	s.-m	s.-m	PROPN
admet-2088	1470	4	.	.	PUNCT
admet-2088	1471	1	hwang	hwang	PROPN
admet-2088	1471	2	,	,	PUNCT
admet-2088	1471	3	l.-c	l.-c	PROPN
admet-2088	1471	4	.	.	PUNCT
admet-2088	1472	1	liao	liao	PROPN
admet-2088	1472	2	,	,	PUNCT
admet-2088	1472	3	y.-j	y.-j	PROPN
admet-2088	1472	4	.	.	PROPN
admet-2088	1472	5	chang	chang	PROPN
admet-2088	1472	6	,	,	PUNCT
admet-2088	1472	7	m.-c	m.-c	PROPN
admet-2088	1472	8	.	.	PUNCT
admet-2088	1473	1	liang	liang	PROPN
admet-2088	1473	2	,	,	PUNCT
admet-2088	1473	3	j.-k	j.-k	PROPN
admet-2088	1473	4	.	.	PUNCT
admet-2088	1474	1	chen	chen	PROPN
admet-2088	1474	2	,	,	PUNCT
admet-2088	1474	3	d.-j	d.-j	PROPN
admet-2088	1474	4	.	.	PUNCT
admet-2088	1475	1	lee	lee	PROPN
admet-2088	1475	2	.	.	PUNCT
admet-2088	1476	1	highly	highly	ADV
admet-2088	1476	2	efficient	efficient	ADJ
admet-2088	1476	3	drug	drug	NOUN
admet-2088	1476	4	delivery	delivery	NOUN
admet-2088	1476	5	systems	system	NOUN
admet-2088	1476	6	based	base	VERB
admet-2088	1476	7	on	on	ADP
admet-2088	1476	8	functional	functional	ADJ
admet-2088	1476	9	supramolecular	supramolecular	ADJ
admet-2088	1476	10	polymers	polymer	NOUN
admet-2088	1476	11	:	:	PUNCT
admet-2088	1476	12	in	in	ADP
admet-2088	1476	13	vitro	vitro	X
admet-2088	1476	14	evaluation	evaluation	NOUN
admet-2088	1476	15	.	.	PUNCT
admet-2088	1477	1	acta	acta	PROPN
admet-2088	1477	2	biomaterialia	biomaterialia	PROPN
admet-2088	1477	3	33	33	NUM
admet-2088	1477	4	(	(	PUNCT
admet-2088	1477	5	2016	2016	NUM
admet-2088	1477	6	)	)	PUNCT
admet-2088	1477	7	194	194	NUM
admet-2088	1477	8	-	-	SYM
admet-2088	1477	9	202	202	NUM
admet-2088	1477	10	.	.	PUNCT
admet-2088	1478	1	https://doi.org/10.1016/j.actbio.2016.01.018	https://doi.org/10.1016/j.actbio.2016.01.018	NOUN
admet-2088	1478	2	.	.	PUNCT
admet-2088	1479	1	[	[	X
admet-2088	1479	2	191	191	NUM
admet-2088	1479	3	]	]	PUNCT
admet-2088	1479	4	s.	s.	PROPN
admet-2088	1479	5	bhat	bhat	PROPN
admet-2088	1479	6	,	,	PUNCT
admet-2088	1479	7	v.	v.	ADP
admet-2088	1479	8	guddadar	guddadar	NOUN
admet-2088	1479	9	.	.	PUNCT
admet-2088	1480	1	targeted	target	VERB
admet-2088	1480	2	therapy	therapy	NOUN
admet-2088	1480	3	in	in	ADP
admet-2088	1480	4	chronic	chronic	ADJ
admet-2088	1480	5	diseases	disease	NOUN
admet-2088	1480	6	treatment	treatment	NOUN
admet-2088	1480	7	by	by	ADP
admet-2088	1480	8	nanomaterial	nanomaterial	NOUN
admet-2088	1480	9	based	base	VERB
admet-2088	1480	10	drug	drug	NOUN
admet-2088	1480	11	delivery	delivery	NOUN
admet-2088	1480	12	.	.	PUNCT
admet-2088	1481	1	international	international	ADJ
admet-2088	1481	2	journal	journal	NOUN
admet-2088	1481	3	of	of	ADP
admet-2088	1481	4	advanced	advanced	ADJ
admet-2088	1481	5	research	research	NOUN
admet-2088	1481	6	in	in	ADP
admet-2088	1481	7	science	science	NOUN
admet-2088	1481	8	,	,	PUNCT
admet-2088	1481	9	communication	communication	NOUN
admet-2088	1481	10	and	and	CCONJ
admet-2088	1481	11	technology	technology	NOUN
admet-2088	1481	12	2	2	NUM
admet-2088	1481	13	(	(	PUNCT
admet-2088	1481	14	2021	2021	NUM
admet-2088	1481	15	)	)	PUNCT
admet-2088	1481	16	141	141	NUM
admet-2088	1481	17	-	-	SYM
admet-2088	1481	18	145	145	NUM
admet-2088	1481	19	,	,	PUNCT
admet-2088	1481	20	https://doi.org/10.48175/ijarsct-799	https://doi.org/10.48175/ijarsct-799	X
admet-2088	1481	21	.	.	PUNCT
admet-2088	1482	1	[	[	X
admet-2088	1482	2	192	192	NUM
admet-2088	1482	3	]	]	X
admet-2088	1482	4	k.	k.	PROPN
admet-2088	1482	5	tokarska	tokarska	PROPN
admet-2088	1482	6	,	,	PUNCT
admet-2088	1482	7	ł	ł	PROPN
admet-2088	1482	8	.	.	PROPN
admet-2088	1482	9	lamch	lamch	PROPN
admet-2088	1482	10	,	,	PUNCT
admet-2088	1482	11	b.	b.	PROPN
admet-2088	1482	12	piechota	piechota	PROPN
admet-2088	1482	13	,	,	PUNCT
admet-2088	1482	14	k.	k.	PROPN
admet-2088	1482	15	żukowski	żukowski	PROPN
admet-2088	1482	16	,	,	PUNCT
admet-2088	1482	17	m.	m.	NOUN
admet-2088	1482	18	chudy	chudy	PROPN
admet-2088	1482	19	,	,	PUNCT
admet-2088	1482	20	k.a	k.a	PROPN
admet-2088	1482	21	.	.	PROPN
admet-2088	1482	22	wilk	wilk	PROPN
admet-2088	1482	23	,	,	PUNCT
admet-2088	1482	24	z.	z.	PROPN
admet-2088	1482	25	brzózka	brzózka	PROPN
admet-2088	1482	26	.	.	PUNCT
admet-2088	1483	1	co	co	NOUN
admet-2088	1483	2	-	-	NOUN
admet-2088	1483	3	delivery	delivery	NOUN
admet-2088	1483	4	of	of	ADP
admet-2088	1483	5	ir-768	ir-768	NOUN
admet-2088	1483	6	and	and	CCONJ
admet-2088	1483	7	daunorubicin	daunorubicin	NOUN
admet-2088	1483	8	using	use	VERB
admet-2088	1483	9	mpeg	mpeg	NOUN
admet-2088	1483	10	-	-	PUNCT
admet-2088	1483	11	b	b	NOUN
admet-2088	1483	12	-	-	PUNCT
admet-2088	1483	13	plga	plga	NOUN
admet-2088	1483	14	micelles	micelle	NOUN
admet-2088	1483	15	for	for	ADP
admet-2088	1483	16	synergistic	synergistic	ADJ
admet-2088	1483	17	enhancement	enhancement	NOUN
admet-2088	1483	18	of	of	ADP
admet-2088	1483	19	combination	combination	NOUN
admet-2088	1483	20	therapy	therapy	NOUN
admet-2088	1483	21	of	of	ADP
admet-2088	1483	22	melanoma	melanoma	PROPN
admet-2088	1483	23	.	.	PUNCT
admet-2088	1484	1	journal	journal	PROPN
admet-2088	1484	2	of	of	ADP
admet-2088	1484	3	photochemistry	photochemistry	NOUN
admet-2088	1484	4	&	&	CCONJ
admet-2088	1484	5	photobiology	photobiology	PROPN
admet-2088	1484	6	,	,	PUNCT
admet-2088	1484	7	b	b	NOUN
admet-2088	1484	8	:	:	PUNCT
admet-2088	1484	9	biology	biology	NOUN
admet-2088	1484	10	211	211	NUM
admet-2088	1484	11	(	(	PUNCT
admet-2088	1484	12	2020	2020	NUM
admet-2088	1484	13	)	)	PUNCT
admet-2088	1484	14	111981	111981	NUM
admet-2088	1484	15	.	.	PUNCT
admet-2088	1485	1	https://doi.org/10.1016/j.jphotobiol.2020.111981	https://doi.org/10.1016/j.jphotobiol.2020.111981	NOUN
admet-2088	1485	2	.	.	PUNCT
admet-2088	1486	1	[	[	X
admet-2088	1486	2	193	193	NUM
admet-2088	1486	3	]	]	X
admet-2088	1486	4	h.-q	h.-q	PROPN
admet-2088	1486	5	.	.	PUNCT
admet-2088	1487	1	wu	wu	PROPN
admet-2088	1487	2	,	,	PUNCT
admet-2088	1487	3	c.	c.	PROPN
admet-2088	1487	4	wang	wang	PROPN
admet-2088	1487	5	.	.	PUNCT
admet-2088	1488	1	biodegradable	biodegradable	ADJ
admet-2088	1488	2	smart	smart	ADJ
admet-2088	1488	3	nanogels	nanogel	NOUN
admet-2088	1488	4	:	:	PUNCT
admet-2088	1488	5	a	a	DET
admet-2088	1488	6	new	new	ADJ
admet-2088	1488	7	platform	platform	NOUN
admet-2088	1488	8	for	for	ADP
admet-2088	1488	9	targeting	target	VERB
admet-2088	1488	10	drug	drug	NOUN
admet-2088	1488	11	delivery	delivery	NOUN
admet-2088	1488	12	and	and	CCONJ
admet-2088	1488	13	biomedical	biomedical	ADJ
admet-2088	1488	14	diagnostics	diagnostic	NOUN
admet-2088	1488	15	.	.	PUNCT
admet-2088	1489	1	langmuir	langmuir	PROPN
admet-2088	1489	2	32	32	NUM
admet-2088	1489	3	(	(	PUNCT
admet-2088	1489	4	2016	2016	NUM
admet-2088	1489	5	)	)	PUNCT
admet-2088	1489	6	6211	6211	NUM
admet-2088	1489	7	-	-	SYM
admet-2088	1489	8	6225	6225	NUM
admet-2088	1489	9	.	.	PUNCT
admet-2088	1490	1	https://doi.org/10.1021/acs.langmuir.6b00842	https://doi.org/10.1021/acs.langmuir.6b00842	PROPN
admet-2088	1490	2	.	.	PUNCT
admet-2088	1491	1	[	[	X
admet-2088	1491	2	194	194	NUM
admet-2088	1491	3	]	]	X
admet-2088	1491	4	w.	w.	PROPN
admet-2088	1491	5	chen	chen	PROPN
admet-2088	1491	6	,	,	PUNCT
admet-2088	1491	7	y.	y.	PROPN
admet-2088	1491	8	hou	hou	PROPN
admet-2088	1491	9	,	,	PUNCT
admet-2088	1491	10	z.	z.	PROPN
admet-2088	1491	11	tu	tu	PROPN
admet-2088	1491	12	,	,	PUNCT
admet-2088	1491	13	l.	l.	PROPN
admet-2088	1491	14	gao	gao	PROPN
admet-2088	1491	15	,	,	PUNCT
admet-2088	1491	16	r.	r.	PROPN
admet-2088	1491	17	haag	haag	PROPN
admet-2088	1491	18	.	.	PUNCT
admet-2088	1492	1	ph	ph	ADJ
admet-2088	1492	2	-	-	ADJ
admet-2088	1492	3	degradable	degradable	ADJ
admet-2088	1492	4	pva	pva	NOUN
admet-2088	1492	5	-	-	PUNCT
admet-2088	1492	6	based	base	VERB
admet-2088	1492	7	nanogels	nanogel	NOUN
admet-2088	1492	8	via	via	ADP
admet-2088	1492	9	photo	photo	NOUN
admet-2088	1492	10	-	-	PUNCT
admet-2088	1492	11	crosslinking	crosslinking	NOUN
admet-2088	1492	12	of	of	ADP
admet-2088	1492	13	thermo	thermo	NOUN
admet-2088	1492	14	-	-	PUNCT
admet-2088	1492	15	preinduced	preinduce	VERB
admet-2088	1492	16	nanoaggregates	nanoaggregate	NOUN
admet-2088	1492	17	for	for	ADP
admet-2088	1492	18	controlled	control	VERB
admet-2088	1492	19	drug	drug	NOUN
admet-2088	1492	20	delivery	delivery	NOUN
admet-2088	1492	21	.	.	PUNCT
admet-2088	1493	1	journal	journal	PROPN
admet-2088	1493	2	of	of	ADP
admet-2088	1493	3	controlled	control	VERB
admet-2088	1493	4	release	release	NOUN
admet-2088	1493	5	16	16	NUM
admet-2088	1493	6	(	(	PUNCT
admet-2088	1493	7	2016	2016	NUM
admet-2088	1493	8	)	)	PUNCT
admet-2088	1493	9	31116	31116	NUM
admet-2088	1493	10	.	.	PUNCT
admet-2088	1494	1	https://doi.org/10.1016/j.jconrel.2016.10.032	https://doi.org/10.1016/j.jconrel.2016.10.032	NOUN
admet-2088	1494	2	.	.	PUNCT
admet-2088	1495	1	[	[	X
admet-2088	1495	2	195	195	NUM
admet-2088	1495	3	]	]	X
admet-2088	1495	4	p.h	p.h	PROPN
admet-2088	1495	5	.	.	PROPN
admet-2088	1495	6	tran	tran	PROPN
admet-2088	1495	7	,	,	PUNCT
admet-2088	1495	8	w.	w.	PROPN
admet-2088	1495	9	duan	duan	PROPN
admet-2088	1495	10	,	,	PUNCT
admet-2088	1495	11	b.-j	b.-j	PROPN
admet-2088	1495	12	.	.	PUNCT
admet-2088	1496	1	lee	lee	PROPN
admet-2088	1496	2	,	,	PUNCT
admet-2088	1496	3	t.t	t.t	PROPN
admet-2088	1496	4	.	.	PROPN
admet-2088	1496	5	tran	tran	PROPN
admet-2088	1496	6	.	.	PUNCT
admet-2088	1497	1	nanogels	nanogel	NOUN
admet-2088	1497	2	for	for	ADP
admet-2088	1497	3	skin	skin	NOUN
admet-2088	1497	4	cancer	cancer	NOUN
admet-2088	1497	5	therapy	therapy	NOUN
admet-2088	1497	6	via	via	ADP
admet-2088	1497	7	transdermal	transdermal	ADJ
admet-2088	1497	8	delivery	delivery	NOUN
admet-2088	1497	9	:	:	PUNCT
admet-2088	1497	10	current	current	ADJ
admet-2088	1497	11	designs	design	NOUN
admet-2088	1497	12	.	.	PUNCT
admet-2088	1498	1	current	current	ADJ
admet-2088	1498	2	drug	drug	NOUN
admet-2088	1498	3	metabolism	metabolism	NOUN
admet-2088	1498	4	20	20	NUM
admet-2088	1498	5	(	(	PUNCT
admet-2088	1498	6	2019	2019	NUM
admet-2088	1498	7	)	)	PUNCT
admet-2088	1498	8	575	575	NUM
admet-2088	1498	9	-	-	SYM
admet-2088	1498	10	582	582	NUM
admet-2088	1498	11	,	,	PUNCT
admet-2088	1498	12	https://doi.org/10.2174/1389200220666190618100030	https://doi.org/10.2174/1389200220666190618100030	X
admet-2088	1498	13	.	.	PUNCT
admet-2088	1499	1	[	[	X
admet-2088	1499	2	196	196	NUM
admet-2088	1499	3	]	]	PUNCT
admet-2088	1499	4	j.	j.	PROPN
admet-2088	1499	5	kousalov´a	kousalov´a	PROPN
admet-2088	1499	6	,	,	PUNCT
admet-2088	1499	7	t.	t.	NOUN
admet-2088	1499	8	etrych	etrych	PROPN
admet-2088	1499	9	.	.	PUNCT
admet-2088	1500	1	polymeric	polymeric	ADJ
admet-2088	1500	2	nanogels	nanogel	NOUN
admet-2088	1500	3	as	as	ADP
admet-2088	1500	4	drug	drug	NOUN
admet-2088	1500	5	delivery	delivery	NOUN
admet-2088	1500	6	systems	system	NOUN
admet-2088	1500	7	.	.	PUNCT
admet-2088	1501	1	physiological	physiological	ADJ
admet-2088	1501	2	research	research	NOUN
admet-2088	1501	3	67	67	NUM
admet-2088	1501	4	(	(	PUNCT
admet-2088	1501	5	2018	2018	NUM
admet-2088	1501	6	)	)	PUNCT
admet-2088	1501	7	.	.	PUNCT
admet-2088	1502	1	https://doi.org/10.33549/physiolres.933979	https://doi.org/10.33549/physiolres.933979	NOUN
admet-2088	1502	2	.	.	PUNCT
admet-2088	1503	1	[	[	X
admet-2088	1503	2	197	197	NUM
admet-2088	1503	3	]	]	X
admet-2088	1503	4	w.	w.	PROPN
admet-2088	1503	5	zhao	zhao	PROPN
admet-2088	1503	6	,	,	PUNCT
admet-2088	1503	7	j.	j.	PROPN
admet-2088	1503	8	hu	hu	PROPN
admet-2088	1503	9	,	,	PUNCT
admet-2088	1503	10	w.	w.	PROPN
admet-2088	1503	11	gao	gao	PROPN
admet-2088	1503	12	.	.	PUNCT
admet-2088	1503	13	glucose	glucose	NOUN
admet-2088	1503	14	oxidase	oxidase	NOUN
admet-2088	1503	15	-	-	PUNCT
admet-2088	1503	16	polymer	polymer	NOUN
admet-2088	1503	17	nanogels	nanogel	NOUN
admet-2088	1503	18	for	for	ADP
admet-2088	1503	19	synergistic	synergistic	ADJ
admet-2088	1503	20	cancer	cancer	NOUN
admet-2088	1503	21	-	-	PUNCT
admet-2088	1503	22	starving	starve	VERB
admet-2088	1503	23	and	and	CCONJ
admet-2088	1503	24	oxidation	oxidation	NOUN
admet-2088	1503	25	therapy	therapy	NOUN
admet-2088	1503	26	.	.	PUNCT
admet-2088	1504	1	acs	acs	PROPN
admet-2088	1504	2	applied	apply	VERB
admet-2088	1504	3	materials	material	NOUN
admet-2088	1504	4	&	&	CCONJ
admet-2088	1504	5	interfaces	interface	NOUN
admet-2088	1504	6	9	9	NUM
admet-2088	1504	7	(	(	PUNCT
admet-2088	1504	8	2017	2017	NUM
admet-2088	1504	9	)	)	PUNCT
admet-2088	1504	10	23528	23528	NUM
admet-2088	1504	11	-	-	SYM
admet-2088	1504	12	23535	23535	NUM
admet-2088	1504	13	.	.	PUNCT
admet-2088	1505	1	https://doi.org/10.1021/acsami.7b06814	https://doi.org/10.1021/acsami.7b06814	NOUN
admet-2088	1505	2	.	.	PUNCT
admet-2088	1506	1	[	[	X
admet-2088	1506	2	198	198	NUM
admet-2088	1506	3	]	]	PUNCT
admet-2088	1506	4	h.	h.	PROPN
admet-2088	1506	5	veisi	veisi	VERB
admet-2088	1506	6	,	,	PUNCT
admet-2088	1506	7	j.	j.	PROPN
admet-2088	1506	8	varshosaz	varshosaz	PROPN
admet-2088	1506	9	,	,	PUNCT
admet-2088	1506	10	m.	m.	NOUN
admet-2088	1506	11	rostami	rostami	PROPN
admet-2088	1506	12	,	,	PUNCT
admet-2088	1506	13	m.	m.	NOUN
admet-2088	1506	14	mirian	mirian	PROPN
admet-2088	1506	15	.	.	PROPN
admet-2088	1507	1	thermosensitive	thermosensitive	PROPN
admet-2088	1507	2	tmpo	tmpo	NOUN
admet-2088	1507	3	-	-	PUNCT
admet-2088	1507	4	oxidized	oxidize	VERB
admet-2088	1507	5	lignocellulose	lignocellulose	NOUN
admet-2088	1507	6	/	/	SYM
admet-2088	1507	7	cationic	cationic	ADJ
admet-2088	1507	8	agarose	agarose	NOUN
admet-2088	1507	9	hydrogel	hydrogel	NOUN
admet-2088	1507	10	loaded	load	VERB
admet-2088	1507	11	with	with	ADP
admet-2088	1507	12	deferasirox	deferasirox	ADJ
admet-2088	1507	13	nanoparticles	nanoparticle	NOUN
admet-2088	1507	14	for	for	ADP
admet-2088	1507	15	photothermal	photothermal	ADJ
admet-2088	1507	16	therapy	therapy	NOUN
admet-2088	1507	17	in	in	ADP
admet-2088	1507	18	melanoma	melanoma	NOUN
admet-2088	1507	19	.	.	PUNCT
admet-2088	1508	1	international	international	ADJ
admet-2088	1508	2	journal	journal	NOUN
admet-2088	1508	3	of	of	ADP
admet-2088	1508	4	biological	biological	ADJ
admet-2088	1508	5	macromolecules	macromolecule	NOUN
admet-2088	1508	6	238	238	NUM
admet-2088	1508	7	(	(	PUNCT
admet-2088	1508	8	2023	2023	NUM
admet-2088	1508	9	)	)	PUNCT
admet-2088	1508	10	124126	124126	NUM
admet-2088	1508	11	.	.	PUNCT
admet-2088	1509	1	https://doi.org/10.1016/j.ijbiomac.2023.124126	https://doi.org/10.1016/j.ijbiomac.2023.124126	NOUN
admet-2088	1509	2	.	.	PUNCT
admet-2088	1510	1	[	[	X
admet-2088	1510	2	199	199	NUM
admet-2088	1510	3	]	]	X
admet-2088	1510	4	b.	b.	PROPN
admet-2088	1510	5	garcía	garcía	NOUN
admet-2088	1510	6	-	-	PUNCT
admet-2088	1510	7	pinel	pinel	NOUN
admet-2088	1510	8	,	,	PUNCT
admet-2088	1510	9	c.	c.	PROPN
admet-2088	1510	10	porras	porras	PROPN
admet-2088	1510	11	-	-	PUNCT
admet-2088	1510	12	alcalá	alcalá	PROPN
admet-2088	1510	13	,	,	PUNCT
admet-2088	1510	14	a.	a.	PROPN
admet-2088	1510	15	ortega	ortega	PROPN
admet-2088	1510	16	-	-	PUNCT
admet-2088	1510	17	rodríguez	rodríguez	PROPN
admet-2088	1510	18	,	,	PUNCT
admet-2088	1510	19	f.	f.	PROPN
admet-2088	1510	20	sarabia	sarabia	PROPN
admet-2088	1510	21	,	,	PUNCT
admet-2088	1510	22	j.	j.	PROPN
admet-2088	1510	23	prados	prados	PROPN
admet-2088	1510	24	,	,	PUNCT
admet-2088	1510	25	c.	c.	PROPN
admet-2088	1510	26	melguizo	melguizo	PROPN
admet-2088	1510	27	,	,	PUNCT
admet-2088	1510	28	j.m	j.m	PROPN
admet-2088	1510	29	.	.	PROPN
admet-2088	1510	30	lópezromero	lópezromero	PROPN
admet-2088	1510	31	.	.	PUNCT
admet-2088	1510	32	lipid	lipid	NOUN
admet-2088	1510	33	-	-	PUNCT
admet-2088	1510	34	based	base	VERB
admet-2088	1510	35	nanoparticles	nanoparticle	NOUN
admet-2088	1510	36	:	:	PUNCT
admet-2088	1510	37	application	application	NOUN
admet-2088	1510	38	and	and	CCONJ
admet-2088	1510	39	recent	recent	ADJ
admet-2088	1510	40	advances	advance	NOUN
admet-2088	1510	41	in	in	ADP
admet-2088	1510	42	cancer	cancer	NOUN
admet-2088	1510	43	treatment	treatment	NOUN
admet-2088	1510	44	.	.	PUNCT
admet-2088	1511	1	nanomaterials	nanomaterial	NOUN
admet-2088	1511	2	9	9	NUM
admet-2088	1511	3	(	(	PUNCT
admet-2088	1511	4	2019	2019	NUM
admet-2088	1511	5	)	)	PUNCT
admet-2088	1511	6	638	638	NUM
admet-2088	1511	7	.	.	PUNCT
admet-2088	1512	1	https://doi.org/0.3390/nano9040638	https://doi.org/0.3390/nano9040638	ADV
admet-2088	1512	2	.	.	PUNCT
admet-2088	1513	1	[	[	X
admet-2088	1513	2	200	200	NUM
admet-2088	1513	3	]	]	PUNCT
admet-2088	1513	4	r.	r.	PROPN
admet-2088	1513	5	kumar	kumar	PROPN
admet-2088	1513	6	.	.	PUNCT
admet-2088	1513	7	lipid	lipid	NOUN
admet-2088	1513	8	-	-	PUNCT
admet-2088	1513	9	based	base	VERB
admet-2088	1513	10	nanoparticles	nanoparticle	NOUN
admet-2088	1513	11	for	for	ADP
admet-2088	1513	12	drug	drug	NOUN
admet-2088	1513	13	-	-	PUNCT
admet-2088	1513	14	delivery	delivery	NOUN
admet-2088	1513	15	systems	system	NOUN
admet-2088	1513	16	,	,	PUNCT
admet-2088	1513	17	in	in	ADP
admet-2088	1513	18	s.s	s.s	PROPN
admet-2088	1513	19	.	.	PROPN
admet-2088	1513	20	mohapatra	mohapatra	PROPN
admet-2088	1513	21	,	,	PUNCT
admet-2088	1513	22	s.	s.	PROPN
admet-2088	1513	23	ranjan	ranjan	PROPN
admet-2088	1513	24	,	,	PUNCT
admet-2088	1513	25	n.	n.	PROPN
admet-2088	1513	26	dasgupta	dasgupta	PROPN
admet-2088	1513	27	,	,	PUNCT
admet-2088	1513	28	r.k	r.k	PROPN
admet-2088	1513	29	.	.	PROPN
admet-2088	1513	30	mishra	mishra	PROPN
admet-2088	1513	31	,	,	PUNCT
admet-2088	1513	32	s.	s.	PROPN
admet-2088	1513	33	thomas	thomas	PROPN
admet-2088	1513	34	(	(	PUNCT
admet-2088	1513	35	eds	eds	PROPN
admet-2088	1513	36	.	.	PUNCT
admet-2088	1513	37	)	)	PUNCT
admet-2088	1513	38	.	.	PUNCT
admet-2088	1514	1	,	,	PUNCT
admet-2088	1514	2	nanocarriers	nanocarrier	VERB
admet-2088	1514	3	for	for	ADP
admet-2088	1514	4	drug	drug	NOUN
admet-2088	1514	5	delivery	delivery	NOUN
admet-2088	1514	6	,	,	PUNCT
admet-2088	1514	7	elsevier	elsevier	NOUN
admet-2088	1514	8	,	,	PUNCT
admet-2088	1514	9	2019	2019	NUM
admet-2088	1514	10	,	,	PUNCT
admet-2088	1514	11	p.	p.	NOUN
admet-2088	1514	12	249	249	NUM
admet-2088	1514	13	-	-	SYM
admet-2088	1514	14	284	284	NUM
admet-2088	1514	15	.	.	PUNCT
admet-2088	1515	1	https://doi.org/10.1016/b978-0-12-814031-4.00003-9	https://doi.org/10.1016/b978-0-12-814031-4.00003-9	NOUN
admet-2088	1515	2	.	.	PUNCT
admet-2088	1516	1	[	[	X
admet-2088	1516	2	201	201	NUM
admet-2088	1516	3	]	]	X
admet-2088	1516	4	a.k	a.k	PROPN
admet-2088	1516	5	.	.	PROPN
admet-2088	1516	6	sah	sah	PROPN
admet-2088	1516	7	,	,	PUNCT
admet-2088	1516	8	a.	a.	PROPN
admet-2088	1516	9	vyas	vyas	PROPN
admet-2088	1516	10	,	,	PUNCT
admet-2088	1516	11	p.k	p.k	PROPN
admet-2088	1516	12	.	.	PROPN
admet-2088	1516	13	suresh	suresh	PROPN
admet-2088	1516	14	,	,	PUNCT
admet-2088	1516	15	b.	b.	PROPN
admet-2088	1516	16	gidwani	gidwani	PROPN
admet-2088	1516	17	.	.	PUNCT
admet-2088	1517	1	application	application	NOUN
admet-2088	1517	2	of	of	ADP
admet-2088	1517	3	nanocarrier	nanocarrier	NOUN
admet-2088	1517	4	based	base	VERB
admet-2088	1517	5	drug	drug	NOUN
admet-2088	1517	6	delivery	delivery	NOUN
admet-2088	1517	7	system	system	NOUN
admet-2088	1517	8	in	in	ADP
admet-2088	1517	9	treatment	treatment	NOUN
admet-2088	1517	10	of	of	ADP
admet-2088	1517	11	oral	oral	ADJ
admet-2088	1517	12	cancer	cancer	NOUN
admet-2088	1517	13	.	.	PUNCT
admet-2088	1518	1	artificial	artificial	ADJ
admet-2088	1518	2	cells	cell	NOUN
admet-2088	1518	3	,	,	PUNCT
admet-2088	1518	4	nanomedicine	nanomedicine	NOUN
admet-2088	1518	5	,	,	PUNCT
admet-2088	1518	6	and	and	CCONJ
admet-2088	1518	7	biotechnology	biotechnology	NOUN
admet-2088	1518	8	46	46	NUM
admet-2088	1518	9	(	(	PUNCT
admet-2088	1518	10	2018	2018	NUM
admet-2088	1518	11	)	)	PUNCT
admet-2088	1518	12	650	650	NUM
admet-2088	1518	13	-	-	SYM
admet-2088	1518	14	657	657	NUM
admet-2088	1518	15	.	.	PUNCT
admet-2088	1519	1	https://doi.org/10.1080/21691401.2017.1373284	https://doi.org/10.1080/21691401.2017.1373284	PROPN
admet-2088	1519	2	.	.	PUNCT
admet-2088	1520	1	[	[	X
admet-2088	1520	2	202	202	NUM
admet-2088	1520	3	]	]	X
admet-2088	1520	4	b.s	b.s	PROPN
admet-2088	1520	5	.	.	PROPN
admet-2088	1520	6	pattni	pattni	PROPN
admet-2088	1520	7	,	,	PUNCT
admet-2088	1520	8	v.v	v.v	PROPN
admet-2088	1520	9	.	.	PROPN
admet-2088	1520	10	chupin	chupin	PROPN
admet-2088	1520	11	,	,	PUNCT
admet-2088	1520	12	v.p	v.p	PROPN
admet-2088	1520	13	.	.	PROPN
admet-2088	1520	14	torchilin	torchilin	PROPN
admet-2088	1520	15	.	.	PUNCT
admet-2088	1521	1	new	new	ADJ
admet-2088	1521	2	developments	development	NOUN
admet-2088	1521	3	in	in	ADP
admet-2088	1521	4	liposomal	liposomal	ADJ
admet-2088	1521	5	drug	drug	NOUN
admet-2088	1521	6	delivery	delivery	NOUN
admet-2088	1521	7	.	.	PUNCT
admet-2088	1522	1	chemical	chemical	ADJ
admet-2088	1522	2	reviews	review	NOUN
admet-2088	1522	3	115	115	NUM
admet-2088	1522	4	(	(	PUNCT
admet-2088	1522	5	2015	2015	NUM
admet-2088	1522	6	)	)	PUNCT
admet-2088	1522	7	10938	10938	NUM
admet-2088	1522	8	-	-	SYM
admet-2088	1522	9	10966	10966	NUM
admet-2088	1522	10	.	.	PUNCT
admet-2088	1523	1	https://doi.org/10.1021/acs.chemrev.5b00046	https://doi.org/10.1021/acs.chemrev.5b00046	ADJ
admet-2088	1523	2	.	.	PUNCT
admet-2088	1524	1	[	[	X
admet-2088	1524	2	203	203	NUM
admet-2088	1524	3	]	]	PUNCT
admet-2088	1524	4	a.	a.	NOUN
admet-2088	1524	5	akbarzadeh	akbarzadeh	PROPN
admet-2088	1524	6	,	,	PUNCT
admet-2088	1524	7	r.	r.	PROPN
admet-2088	1524	8	rezaei	rezaei	PROPN
admet-2088	1524	9	-	-	PUNCT
admet-2088	1524	10	sadabady	sadabady	PROPN
admet-2088	1524	11	,	,	PUNCT
admet-2088	1524	12	s.	s.	PROPN
admet-2088	1524	13	davaran	davaran	PROPN
admet-2088	1524	14	,	,	PUNCT
admet-2088	1524	15	s.w	s.w	PROPN
admet-2088	1524	16	.	.	PROPN
admet-2088	1524	17	joo	joo	PROPN
admet-2088	1524	18	,	,	PUNCT
admet-2088	1524	19	n.	n.	PROPN
admet-2088	1524	20	zarghami	zarghami	PROPN
admet-2088	1524	21	,	,	PUNCT
admet-2088	1524	22	y.	y.	PROPN
admet-2088	1524	23	hanifehpour	hanifehpour	PROPN
admet-2088	1524	24	,	,	PUNCT
admet-2088	1524	25	md	md	PROPN
admet-2088	1524	26	.	.	PROPN
admet-2088	1524	27	samiei	samiei	PROPN
admet-2088	1524	28	,	,	PUNCT
admet-2088	1524	29	md	md	PROPN
admet-2088	1524	30	.	.	PROPN
admet-2088	1524	31	kouhi	kouhi	PROPN
admet-2088	1524	32	,	,	PUNCT
admet-2088	1524	33	k.	k.	PROPN
admet-2088	1524	34	nejati	nejati	PROPN
admet-2088	1524	35	-	-	PUNCT
admet-2088	1524	36	koshki	koshki	PROPN
admet-2088	1524	37	.	.	PUNCT
admet-2088	1525	1	liposome	liposome	NOUN
admet-2088	1525	2	:	:	PUNCT
admet-2088	1525	3	classification	classification	NOUN
admet-2088	1525	4	,	,	PUNCT
admet-2088	1525	5	preparation	preparation	NOUN
admet-2088	1525	6	,	,	PUNCT
admet-2088	1525	7	and	and	CCONJ
admet-2088	1525	8	applications	application	NOUN
admet-2088	1525	9	.	.	PUNCT
admet-2088	1526	1	nanoscale	nanoscale	NOUN
admet-2088	1526	2	research	research	NOUN
admet-2088	1526	3	letters	letter	NOUN
admet-2088	1526	4	8	8	NUM
admet-2088	1526	5	(	(	PUNCT
admet-2088	1526	6	2013	2013	NUM
admet-2088	1526	7	)	)	PUNCT
admet-2088	1526	8	102	102	NUM
admet-2088	1526	9	.	.	PUNCT
admet-2088	1527	1	https://doi.org/10.1186/1556-276x-8-102	https://doi.org/10.1186/1556-276x-8-102	NUM
admet-2088	1527	2	.	.	PUNCT
admet-2088	1528	1	[	[	X
admet-2088	1528	2	204	204	NUM
admet-2088	1528	3	]	]	PUNCT
admet-2088	1528	4	v.	v.	X
admet-2088	1528	5	krishnan	krishnan	PROPN
admet-2088	1528	6	,	,	PUNCT
admet-2088	1528	7	s.	s.	PROPN
admet-2088	1528	8	mitragotri	mitragotri	PROPN
admet-2088	1528	9	.	.	PUNCT
admet-2088	1529	1	nanoparticles	nanoparticle	NOUN
admet-2088	1529	2	for	for	ADP
admet-2088	1529	3	topical	topical	ADJ
admet-2088	1529	4	drug	drug	NOUN
admet-2088	1529	5	delivery	delivery	NOUN
admet-2088	1529	6	:	:	PUNCT
admet-2088	1529	7	potential	potential	NOUN
admet-2088	1529	8	for	for	ADP
admet-2088	1529	9	skin	skin	NOUN
admet-2088	1529	10	cancer	cancer	NOUN
admet-2088	1529	11	treatment	treatment	NOUN
admet-2088	1529	12	.	.	PUNCT
admet-2088	1530	1	advanced	advanced	ADJ
admet-2088	1530	2	drug	drug	NOUN
admet-2088	1530	3	delivery	delivery	NOUN
admet-2088	1530	4	reviews	review	VERB
admet-2088	1530	5	153	153	NUM
admet-2088	1530	6	(	(	PUNCT
admet-2088	1530	7	2020	2020	NUM
admet-2088	1530	8	)	)	PUNCT
admet-2088	1530	9	87	87	NUM
admet-2088	1530	10	-	-	SYM
admet-2088	1530	11	108	108	NUM
admet-2088	1530	12	.	.	PUNCT
admet-2088	1531	1	https://doi.org/10.1016/j.addr.2020.05.011	https://doi.org/10.1016/j.addr.2020.05.011	PROPN
admet-2088	1531	2	.	.	PUNCT
admet-2088	1532	1	[	[	X
admet-2088	1532	2	205	205	NUM
admet-2088	1532	3	]	]	X
admet-2088	1532	4	h.	h.	PROPN
admet-2088	1532	5	daraee	daraee	PROPN
admet-2088	1532	6	,	,	PUNCT
admet-2088	1532	7	a.	a.	NOUN
admet-2088	1532	8	etemadi	etemadi	PROPN
admet-2088	1532	9	,	,	PUNCT
admet-2088	1532	10	m.	m.	NOUN
admet-2088	1532	11	kouhi	kouhi	PROPN
admet-2088	1532	12	,	,	PUNCT
admet-2088	1532	13	s.	s.	PROPN
admet-2088	1532	14	alimirzalu	alimirzalu	PROPN
admet-2088	1532	15	,	,	PUNCT
admet-2088	1532	16	a.	a.	NOUN
admet-2088	1532	17	akbarzadeh	akbarzadeh	PROPN
admet-2088	1532	18	.	.	PUNCT
admet-2088	1533	1	application	application	NOUN
admet-2088	1533	2	of	of	ADP
admet-2088	1533	3	liposomes	liposome	NOUN
admet-2088	1533	4	in	in	ADP
admet-2088	1533	5	medicine	medicine	NOUN
admet-2088	1533	6	and	and	CCONJ
admet-2088	1533	7	drug	drug	NOUN
admet-2088	1533	8	delivery	delivery	NOUN
admet-2088	1533	9	.	.	PUNCT
admet-2088	1534	1	artificial	artificial	ADJ
admet-2088	1534	2	cells	cell	NOUN
admet-2088	1534	3	,	,	PUNCT
admet-2088	1534	4	nanomedicine	nanomedicine	NOUN
admet-2088	1534	5	,	,	PUNCT
admet-2088	1534	6	and	and	CCONJ
admet-2088	1534	7	biotechnology	biotechnology	NOUN
admet-2088	1534	8	44	44	NUM
admet-2088	1534	9	(	(	PUNCT
admet-2088	1534	10	2016	2016	NUM
admet-2088	1534	11	)	)	PUNCT
admet-2088	1534	12	381	381	NUM
admet-2088	1534	13	-	-	SYM
admet-2088	1534	14	391	391	NUM
admet-2088	1534	15	.	.	PUNCT
admet-2088	1535	1	https://doi.org/10.3109/21691401.2014.953633	https://doi.org/10.3109/21691401.2014.953633	NOUN
admet-2088	1535	2	.	.	PUNCT
admet-2088	1536	1	https://doi.org/10.3892/or.2016.5342	https://doi.org/10.3892/or.2016.5342	PROPN
admet-2088	1536	2	https://doi.org/10.1016/j.actbio.2016.01.018	https://doi.org/10.1016/j.actbio.2016.01.018	PROPN
admet-2088	1536	3	https://doi.org/10.48175/ijarsct-799	https://doi.org/10.48175/ijarsct-799	PROPN
admet-2088	1536	4	https://doi.org/10.1016/j.jphotobiol.2020.111981	https://doi.org/10.1016/j.jphotobiol.2020.111981	VERB
admet-2088	1536	5	https://doi.org/10.1021/acs.langmuir.6b00842	https://doi.org/10.1021/acs.langmuir.6b00842	PROPN
admet-2088	1536	6	https://doi.org/10.1016/j.jconrel.2016.10.032	https://doi.org/10.1016/j.jconrel.2016.10.032	NUM
admet-2088	1536	7	https://doi.org/10.2174/1389200220666190618100030	https://doi.org/10.2174/1389200220666190618100030	NOUN
admet-2088	1536	8	https://doi.org/10.33549/physiolres.933979	https://doi.org/10.33549/physiolres.933979	NOUN
admet-2088	1536	9	https://doi.org/10.1021/acsami.7b06814	https://doi.org/10.1021/acsami.7b06814	NOUN
admet-2088	1536	10	https://doi.org/10.1016/j.ijbiomac.2023.124126	https://doi.org/10.1016/j.ijbiomac.2023.124126	NOUN
admet-2088	1536	11	https://doi.org/0.3390/nano9040638	https://doi.org/0.3390/nano9040638	PART
admet-2088	1537	1	https://doi.org/10.1016/b978-0-12-814031-4.00003-9	https://doi.org/10.1016/b978-0-12-814031-4.00003-9	PROPN
admet-2088	1537	2	https://doi.org/10.1080/21691401.2017.1373284	https://doi.org/10.1080/21691401.2017.1373284	PROPN
admet-2088	1538	1	https://doi.org/10.1021/acs.chemrev.5b00046	https://doi.org/10.1021/acs.chemrev.5b00046	INTJ
admet-2088	1538	2	https://doi.org/10.1186/1556-276x-8-102	https://doi.org/10.1186/1556-276x-8-102	PRON
admet-2088	1538	3	https://doi.org/10.1016/j.addr.2020.05.011	https://doi.org/10.1016/j.addr.2020.05.011	PROPN
admet-2088	1538	4	https://doi.org/10.3109/21691401.2014.953633	https://doi.org/10.3109/21691401.2014.953633	X
admet-2088	1538	5	admet	admet	PROPN
admet-2088	1538	6	&	&	CCONJ
admet-2088	1538	7	dmpk	dmpk	PROPN
admet-2088	1538	8	12(1	12(1	PROPN
admet-2088	1538	9	)	)	PUNCT
admet-2088	1538	10	(	(	PUNCT
admet-2088	1538	11	2024	2024	NUM
admet-2088	1538	12	)	)	PUNCT
admet-2088	1538	13	107	107	NUM
admet-2088	1538	14	-	-	SYM
admet-2088	1538	15	150	150	NUM
admet-2088	1538	16	nanomaterial	nanomaterial	NOUN
admet-2088	1538	17	-	-	PUNCT
admet-2088	1538	18	based	base	VERB
admet-2088	1538	19	drug	drug	NOUN
admet-2088	1538	20	delivery	delivery	NOUN
admet-2088	1538	21	systems	system	NOUN
admet-2088	1538	22	for	for	ADP
admet-2088	1538	23	melanoma	melanoma	NOUN
admet-2088	1538	24	therapy	therapy	NOUN
admet-2088	1538	25	doi	doi	NOUN
admet-2088	1538	26	:	:	PUNCT
admet-2088	1538	27	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	NOUN
admet-2088	1538	28	149	149	NUM
admet-2088	1538	29	[	[	X
admet-2088	1538	30	206	206	NUM
admet-2088	1538	31	]	]	PUNCT
admet-2088	1538	32	a.	a.	NOUN
admet-2088	1538	33	ahmadi	ahmadi	PROPN
admet-2088	1538	34	,	,	PUNCT
admet-2088	1538	35	s.	s.	PROPN
admet-2088	1538	36	hosseini	hosseini	PROPN
admet-2088	1538	37	-	-	PUNCT
admet-2088	1538	38	nami	nami	PROPN
admet-2088	1538	39	,	,	PUNCT
admet-2088	1538	40	z.	z.	PROPN
admet-2088	1538	41	abed	abed	PROPN
admet-2088	1538	42	,	,	PUNCT
admet-2088	1538	43	j.	j.	PROPN
admet-2088	1538	44	beik	beik	PROPN
admet-2088	1538	45	,	,	PUNCT
admet-2088	1538	46	l.	l.	PROPN
admet-2088	1538	47	aranda	aranda	PROPN
admet-2088	1538	48	-	-	PUNCT
admet-2088	1538	49	lara	lara	PROPN
admet-2088	1538	50	,	,	PUNCT
admet-2088	1538	51	h.	h.	PROPN
admet-2088	1538	52	samadian	samadian	PROPN
admet-2088	1538	53	,	,	PUNCT
admet-2088	1538	54	e.	e.	PROPN
admet-2088	1538	55	morales	morales	PROPN
admet-2088	1538	56	-	-	PUNCT
admet-2088	1538	57	avila	avila	PROPN
admet-2088	1538	58	,	,	PUNCT
admet-2088	1538	59	m.	m.	NOUN
admet-2088	1538	60	jaymand	jaymand	PROPN
admet-2088	1538	61	,	,	PUNCT
admet-2088	1538	62	a.	a.	PROPN
admet-2088	1538	63	shakeri	shakeri	PROPN
admet-2088	1538	64	-	-	PUNCT
admet-2088	1538	65	zadeh	zadeh	PROPN
admet-2088	1538	66	.	.	PUNCT
admet-2088	1539	1	recent	recent	ADJ
admet-2088	1539	2	advances	advance	NOUN
admet-2088	1539	3	in	in	ADP
admet-2088	1539	4	ultrasound	ultrasound	NOUN
admet-2088	1539	5	triggered	trigger	VERB
admet-2088	1539	6	drug	drug	NOUN
admet-2088	1539	7	delivery	delivery	NOUN
admet-2088	1539	8	through	through	ADP
admet-2088	1539	9	lipidbased	lipidbase	VERB
admet-2088	1539	10	nanomaterials	nanomaterial	NOUN
admet-2088	1539	11	.	.	PUNCT
admet-2088	1540	1	drug	drug	NOUN
admet-2088	1540	2	discovery	discovery	PROPN
admet-2088	1540	3	today	today	NOUN
admet-2088	1540	4	25	25	NUM
admet-2088	1540	5	(	(	PUNCT
admet-2088	1540	6	2020	2020	NUM
admet-2088	1540	7	)	)	PUNCT
admet-2088	1540	8	2182	2182	NUM
admet-2088	1540	9	-	-	SYM
admet-2088	1540	10	2200	2200	NUM
admet-2088	1540	11	.	.	PUNCT
admet-2088	1541	1	https://doi.org/10.1016/j.drudis.2020.09.026	https://doi.org/10.1016/j.drudis.2020.09.026	PROPN
admet-2088	1541	2	.	.	PUNCT
admet-2088	1542	1	[	[	X
admet-2088	1542	2	207	207	NUM
admet-2088	1542	3	]	]	X
admet-2088	1542	4	v.	v.	CCONJ
admet-2088	1542	5	jahani	jahani	PROPN
admet-2088	1542	6	,	,	PUNCT
admet-2088	1542	7	m.	m.	NOUN
admet-2088	1542	8	yazdani	yazdani	PROPN
admet-2088	1542	9	,	,	PUNCT
admet-2088	1542	10	a.	a.	NOUN
admet-2088	1542	11	badiee	badiee	PROPN
admet-2088	1542	12	,	,	PUNCT
admet-2088	1542	13	m.r	m.r	PROPN
admet-2088	1542	14	.	.	PROPN
admet-2088	1542	15	jaafari	jaafari	PROPN
admet-2088	1542	16	,	,	PUNCT
admet-2088	1542	17	l.	l.	PROPN
admet-2088	1542	18	arabi	arabi	PROPN
admet-2088	1542	19	.	.	PUNCT
admet-2088	1543	1	liposomal	liposomal	PROPN
admet-2088	1543	2	celecoxib	celecoxib	PROPN
admet-2088	1543	3	combined	combine	VERB
admet-2088	1543	4	with	with	ADP
admet-2088	1543	5	dendritic	dendritic	ADJ
admet-2088	1543	6	cell	cell	NOUN
admet-2088	1543	7	therapy	therapy	NOUN
admet-2088	1543	8	enhances	enhance	VERB
admet-2088	1543	9	antitumor	antitumor	PROPN
admet-2088	1543	10	efficacy	efficacy	NOUN
admet-2088	1543	11	in	in	ADP
admet-2088	1543	12	melanoma	melanoma	NOUN
admet-2088	1543	13	.	.	PUNCT
admet-2088	1544	1	journal	journal	PROPN
admet-2088	1544	2	of	of	ADP
admet-2088	1544	3	controlled	control	VERB
admet-2088	1544	4	release	release	NOUN
admet-2088	1544	5	354	354	NUM
admet-2088	1544	6	(	(	PUNCT
admet-2088	1544	7	2023	2023	NUM
admet-2088	1544	8	)	)	PUNCT
admet-2088	1544	9	453	453	NUM
admet-2088	1544	10	-	-	SYM
admet-2088	1544	11	464	464	NUM
admet-2088	1544	12	.	.	PUNCT
admet-2088	1545	1	https://doi.org/10.1016/j.jconrel.2023.01.034	https://doi.org/10.1016/j.jconrel.2023.01.034	NOUN
admet-2088	1545	2	.	.	PUNCT
admet-2088	1546	1	[	[	X
admet-2088	1546	2	208	208	NUM
admet-2088	1546	3	]	]	X
admet-2088	1546	4	e.h	e.h	PROPN
admet-2088	1546	5	.	.	PROPN
admet-2088	1546	6	lee	lee	PROPN
admet-2088	1546	7	,	,	PUNCT
admet-2088	1546	8	s.j	s.j	PROPN
admet-2088	1546	9	.	.	PROPN
admet-2088	1546	10	lim	lim	PROPN
admet-2088	1546	11	,	,	PUNCT
admet-2088	1546	12	m.k	m.k	PROPN
admet-2088	1546	13	.	.	PUNCT
admet-2088	1546	14	lee	lee	PROPN
admet-2088	1546	15	.	.	PUNCT
admet-2088	1547	1	chitosan	chitosan	NOUN
admet-2088	1547	2	-	-	PUNCT
admet-2088	1547	3	coated	coat	VERB
admet-2088	1547	4	liposomes	liposome	NOUN
admet-2088	1547	5	to	to	PART
admet-2088	1547	6	stabilize	stabilize	VERB
admet-2088	1547	7	and	and	CCONJ
admet-2088	1547	8	enhance	enhance	VERB
admet-2088	1547	9	transdermal	transdermal	ADJ
admet-2088	1547	10	delivery	delivery	NOUN
admet-2088	1547	11	of	of	ADP
admet-2088	1547	12	indocyanine	indocyanine	NOUN
admet-2088	1547	13	green	green	ADJ
admet-2088	1547	14	for	for	ADP
admet-2088	1547	15	photodynamic	photodynamic	ADJ
admet-2088	1547	16	therapy	therapy	NOUN
admet-2088	1547	17	of	of	ADP
admet-2088	1547	18	melanoma	melanoma	NOUN
admet-2088	1547	19	.	.	PUNCT
admet-2088	1548	1	carbohydrate	carbohydrate	VERB
admet-2088	1548	2	polymer	polymer	NOUN
admet-2088	1548	3	224	224	NUM
admet-2088	1548	4	(	(	PUNCT
admet-2088	1548	5	2019	2019	NUM
admet-2088	1548	6	)	)	PUNCT
admet-2088	1548	7	115	115	NUM
admet-2088	1548	8	-	-	SYM
admet-2088	1548	9	143	143	NUM
admet-2088	1548	10	.	.	PUNCT
admet-2088	1549	1	https://doi.org/10.1016/j.carbpol.2019.115143	https://doi.org/10.1016/j.carbpol.2019.115143	NOUN
admet-2088	1549	2	.	.	PUNCT
admet-2088	1550	1	[	[	X
admet-2088	1550	2	209	209	NUM
admet-2088	1550	3	]	]	X
admet-2088	1550	4	h.	h.	PROPN
admet-2088	1550	5	mishra	mishra	PROPN
admet-2088	1550	6	,	,	PUNCT
admet-2088	1550	7	p.k	p.k	PROPN
admet-2088	1550	8	.	.	PUNCT
admet-2088	1550	9	mishra	mishra	PROPN
admet-2088	1550	10	,	,	PUNCT
admet-2088	1550	11	z.	z.	PROPN
admet-2088	1550	12	iqbal	iqbal	PROPN
admet-2088	1550	13	,	,	PUNCT
admet-2088	1550	14	m.	m.	NOUN
admet-2088	1550	15	jaggi	jaggi	PROPN
admet-2088	1550	16	,	,	PUNCT
admet-2088	1550	17	a.	a.	PROPN
admet-2088	1550	18	madaan	madaan	PROPN
admet-2088	1550	19	,	,	PUNCT
admet-2088	1550	20	k.	k.	PROPN
admet-2088	1550	21	bhuyan	bhuyan	PROPN
admet-2088	1550	22	,	,	PUNCT
admet-2088	1550	23	n.	n.	PROPN
admet-2088	1550	24	gupta	gupta	PROPN
admet-2088	1550	25	,	,	PUNCT
admet-2088	1550	26	n.	n.	PROPN
admet-2088	1550	27	gupta	gupta	PROPN
admet-2088	1550	28	,	,	PUNCT
admet-2088	1550	29	k.	k.	PROPN
admet-2088	1550	30	vats	vat	NOUN
admet-2088	1550	31	,	,	PUNCT
admet-2088	1550	32	r.	r.	PROPN
admet-2088	1550	33	verma	verma	PROPN
admet-2088	1550	34	,	,	PUNCT
admet-2088	1550	35	s.	s.	PROPN
admet-2088	1550	36	talegaonkar	talegaonkar	PROPN
admet-2088	1550	37	.	.	PUNCT
admet-2088	1551	1	co	co	NOUN
admet-2088	1551	2	-	-	NOUN
admet-2088	1551	3	delivery	delivery	NOUN
admet-2088	1551	4	of	of	ADP
admet-2088	1551	5	eugenol	eugenol	NOUN
admet-2088	1551	6	and	and	CCONJ
admet-2088	1551	7	dacarbazine	dacarbazine	NOUN
admet-2088	1551	8	by	by	ADP
admet-2088	1551	9	hyaluronic	hyaluronic	ADJ
admet-2088	1551	10	acid	acid	NOUN
admet-2088	1551	11	-	-	PUNCT
admet-2088	1551	12	coated	coat	VERB
admet-2088	1551	13	liposomes	liposome	NOUN
admet-2088	1551	14	for	for	ADP
admet-2088	1551	15	targeted	target	VERB
admet-2088	1551	16	inhibition	inhibition	NOUN
admet-2088	1551	17	of	of	ADP
admet-2088	1551	18	survivin	survivin	PROPN
admet-2088	1551	19	in	in	ADP
admet-2088	1551	20	treatment	treatment	NOUN
admet-2088	1551	21	of	of	ADP
admet-2088	1551	22	resistant	resistant	ADJ
admet-2088	1551	23	metastatic	metastatic	ADJ
admet-2088	1551	24	melanoma	melanoma	NOUN
admet-2088	1551	25	.	.	PUNCT
admet-2088	1552	1	pharmaceutics	pharmaceutic	NOUN
admet-2088	1552	2	11	11	NUM
admet-2088	1552	3	(	(	PUNCT
admet-2088	1552	4	2019	2019	NUM
admet-2088	1552	5	)	)	PUNCT
admet-2088	1552	6	163	163	NUM
admet-2088	1552	7	.	.	PUNCT
admet-2088	1552	8	https://doi.org/10.3390/pharmaceutics11040163	https://doi.org/10.3390/pharmaceutics11040163	NOUN
admet-2088	1552	9	.	.	PUNCT
admet-2088	1553	1	[	[	X
admet-2088	1553	2	210	210	NUM
admet-2088	1553	3	]	]	X
admet-2088	1553	4	a.n	a.n	PROPN
admet-2088	1553	5	.	.	PROPN
admet-2088	1553	6	cadinoiu	cadinoiu	PROPN
admet-2088	1553	7	,	,	PUNCT
admet-2088	1553	8	d.m	d.m	PROPN
admet-2088	1553	9	.	.	PROPN
admet-2088	1553	10	rata	rata	PROPN
admet-2088	1553	11	,	,	PUNCT
admet-2088	1553	12	l.i	l.i	PROPN
admet-2088	1553	13	.	.	PROPN
admet-2088	1553	14	atanase	atanase	PROPN
admet-2088	1553	15	,	,	PUNCT
admet-2088	1553	16	o.m	o.m	PROPN
admet-2088	1553	17	.	.	PROPN
admet-2088	1553	18	daraba	daraba	PROPN
admet-2088	1553	19	,	,	PUNCT
admet-2088	1553	20	d.	d.	PROPN
admet-2088	1553	21	gherghel	gherghel	PROPN
admet-2088	1553	22	,	,	PUNCT
admet-2088	1553	23	g.	g.	PROPN
admet-2088	1553	24	vochita	vochita	PROPN
admet-2088	1553	25	,	,	PUNCT
admet-2088	1553	26	m.	m.	NOUN
admet-2088	1553	27	popa	popa	NOUN
admet-2088	1553	28	.	.	PUNCT
admet-2088	1554	1	aptamerfunctionalized	aptamerfunctionalize	VERB
admet-2088	1554	2	liposomes	liposome	NOUN
admet-2088	1554	3	as	as	ADP
admet-2088	1554	4	a	a	DET
admet-2088	1554	5	potential	potential	ADJ
admet-2088	1554	6	treatment	treatment	NOUN
admet-2088	1554	7	for	for	ADP
admet-2088	1554	8	basal	basal	ADJ
admet-2088	1554	9	cell	cell	NOUN
admet-2088	1554	10	carcinoma	carcinoma	NOUN
admet-2088	1554	11	.	.	PUNCT
admet-2088	1555	1	polymers	polymer	NOUN
admet-2088	1555	2	11	11	NUM
admet-2088	1555	3	(	(	PUNCT
admet-2088	1555	4	2019	2019	NUM
admet-2088	1555	5	)	)	PUNCT
admet-2088	1555	6	1515	1515	NUM
admet-2088	1555	7	.	.	PUNCT
admet-2088	1556	1	https://doi.org/10.3390/polym11091515	https://doi.org/10.3390/polym11091515	NOUN
admet-2088	1556	2	.	.	PUNCT
admet-2088	1557	1	[	[	X
admet-2088	1557	2	211	211	NUM
admet-2088	1557	3	]	]	PUNCT
admet-2088	1557	4	m.	m.	NOUN
admet-2088	1557	5	hadjidemetriou	hadjidemetriou	PROPN
admet-2088	1557	6	,	,	PUNCT
admet-2088	1557	7	z.	z.	PROPN
admet-2088	1557	8	al	al	PROPN
admet-2088	1557	9	-	-	PUNCT
admet-2088	1557	10	ahmady	ahmady	PROPN
admet-2088	1557	11	,	,	PUNCT
admet-2088	1557	12	m.	m.	NOUN
admet-2088	1557	13	buggio	buggio	PROPN
admet-2088	1557	14	,	,	PUNCT
admet-2088	1557	15	j.	j.	PROPN
admet-2088	1557	16	swift	swift	PROPN
admet-2088	1557	17	,	,	PUNCT
admet-2088	1557	18	k.	k.	PROPN
admet-2088	1557	19	kostarelos	kostarelos	PROPN
admet-2088	1557	20	.	.	PUNCT
admet-2088	1558	1	a	a	DET
admet-2088	1558	2	novel	novel	NOUN
admet-2088	1558	3	scavenging	scavenge	VERB
admet-2088	1558	4	tool	tool	NOUN
admet-2088	1558	5	for	for	ADP
admet-2088	1558	6	cancer	cancer	NOUN
admet-2088	1558	7	biomarker	biomarker	NOUN
admet-2088	1558	8	discovery	discovery	NOUN
admet-2088	1558	9	based	base	VERB
admet-2088	1558	10	on	on	ADP
admet-2088	1558	11	the	the	DET
admet-2088	1558	12	blood	blood	NOUN
admet-2088	1558	13	-	-	PUNCT
admet-2088	1558	14	circulating	circulate	VERB
admet-2088	1558	15	nanoparticle	nanoparticle	NOUN
admet-2088	1558	16	protein	protein	NOUN
admet-2088	1558	17	corona	corona	PROPN
admet-2088	1558	18	.	.	PUNCT
admet-2088	1559	1	biomaterials	biomaterial	NOUN
admet-2088	1559	2	188	188	NUM
admet-2088	1559	3	(	(	PUNCT
admet-2088	1559	4	2019	2019	NUM
admet-2088	1559	5	)	)	PUNCT
admet-2088	1559	6	118	118	NUM
admet-2088	1559	7	-	-	SYM
admet-2088	1559	8	129	129	NUM
admet-2088	1559	9	.	.	PUNCT
admet-2088	1560	1	https://doi.org/10.1016/j.biomaterials.2018.10.011	https://doi.org/10.1016/j.biomaterials.2018.10.011	X
admet-2088	1560	2	.	.	PUNCT
admet-2088	1561	1	[	[	X
admet-2088	1561	2	212	212	NUM
admet-2088	1561	3	]	]	X
admet-2088	1561	4	p.l	p.l	PROPN
admet-2088	1561	5	.	.	PROPN
admet-2088	1561	6	yeo	yeo	PROPN
admet-2088	1561	7	,	,	PUNCT
admet-2088	1561	8	c.l	c.l	PROPN
admet-2088	1561	9	.	.	PROPN
admet-2088	1561	10	lim	lim	PROPN
admet-2088	1561	11	,	,	PUNCT
admet-2088	1561	12	s.m	s.m	PROPN
admet-2088	1561	13	.	.	PROPN
admet-2088	1561	14	chye	chye	PROPN
admet-2088	1561	15	,	,	PUNCT
admet-2088	1561	16	a.p.k	a.p.k	PROPN
admet-2088	1561	17	.	.	PUNCT
admet-2088	1562	1	ling	ling	PROPN
admet-2088	1562	2	,	,	PUNCT
admet-2088	1562	3	r.y	r.y	PROPN
admet-2088	1562	4	.	.	PROPN
admet-2088	1562	5	koh	koh	PROPN
admet-2088	1562	6	.	.	PUNCT
admet-2088	1563	1	niosomes	niosome	NOUN
admet-2088	1563	2	:	:	PUNCT
admet-2088	1563	3	a	a	DET
admet-2088	1563	4	review	review	NOUN
admet-2088	1563	5	of	of	ADP
admet-2088	1563	6	their	their	PRON
admet-2088	1563	7	structure	structure	NOUN
admet-2088	1563	8	,	,	PUNCT
admet-2088	1563	9	properties	property	NOUN
admet-2088	1563	10	,	,	PUNCT
admet-2088	1563	11	methods	method	NOUN
admet-2088	1563	12	of	of	ADP
admet-2088	1563	13	preparation	preparation	NOUN
admet-2088	1563	14	,	,	PUNCT
admet-2088	1563	15	and	and	CCONJ
admet-2088	1563	16	medical	medical	ADJ
admet-2088	1563	17	applications	application	NOUN
admet-2088	1563	18	.	.	PUNCT
admet-2088	1564	1	asian	asian	ADJ
admet-2088	1564	2	biomedicine	biomedicine	NOUN
admet-2088	1564	3	11	11	NUM
admet-2088	1564	4	(	(	PUNCT
admet-2088	1564	5	2017	2017	NUM
admet-2088	1564	6	)	)	PUNCT
admet-2088	1564	7	301	301	NUM
admet-2088	1564	8	-	-	SYM
admet-2088	1564	9	314	314	NUM
admet-2088	1564	10	.	.	PUNCT
admet-2088	1564	11	https://doi.org/10.1515/abm-2018-0002	https://doi.org/10.1515/abm-2018-0002	NOUN
admet-2088	1564	12	.	.	PUNCT
admet-2088	1565	1	[	[	X
admet-2088	1565	2	213	213	NUM
admet-2088	1565	3	]	]	PUNCT
admet-2088	1565	4	m.	m.	NOUN
admet-2088	1565	5	gharbavi	gharbavi	NOUN
admet-2088	1565	6	,	,	PUNCT
admet-2088	1565	7	b.	b.	PROPN
admet-2088	1565	8	johari	johari	PROPN
admet-2088	1565	9	,	,	PUNCT
admet-2088	1565	10	n.	n.	PROPN
admet-2088	1565	11	mousazadeh	mousazadeh	PROPN
admet-2088	1565	12	,	,	PUNCT
admet-2088	1565	13	b.	b.	PROPN
admet-2088	1565	14	rahimi	rahimi	PROPN
admet-2088	1565	15	,	,	PUNCT
admet-2088	1565	16	m.p	m.p	PROPN
admet-2088	1565	17	.	.	PROPN
admet-2088	1565	18	leilan	leilan	PROPN
admet-2088	1565	19	,	,	PUNCT
admet-2088	1565	20	s.s	s.s	PROPN
admet-2088	1565	21	.	.	PROPN
admet-2088	1565	22	eslami	eslami	PROPN
admet-2088	1565	23	,	,	PUNCT
admet-2088	1565	24	a.	a.	NOUN
admet-2088	1565	25	sharafi	sharafi	PROPN
admet-2088	1565	26	.	.	PUNCT
admet-2088	1566	1	hybrid	hybrid	NOUN
admet-2088	1566	2	of	of	ADP
admet-2088	1566	3	niosomes	niosome	NOUN
admet-2088	1566	4	and	and	CCONJ
admet-2088	1566	5	bio	bio	ADV
admet-2088	1566	6	-	-	PUNCT
admet-2088	1566	7	synthesized	synthesize	VERB
admet-2088	1566	8	selenium	selenium	NOUN
admet-2088	1566	9	nanoparticles	nanoparticle	NOUN
admet-2088	1566	10	as	as	ADP
admet-2088	1566	11	a	a	DET
admet-2088	1566	12	novel	novel	ADJ
admet-2088	1566	13	approach	approach	NOUN
admet-2088	1566	14	in	in	ADP
admet-2088	1566	15	drug	drug	NOUN
admet-2088	1566	16	delivery	delivery	NOUN
admet-2088	1566	17	for	for	ADP
admet-2088	1566	18	cancer	cancer	NOUN
admet-2088	1566	19	treatment	treatment	NOUN
admet-2088	1566	20	.	.	PUNCT
admet-2088	1567	1	molecular	molecular	ADJ
admet-2088	1567	2	biology	biology	NOUN
admet-2088	1567	3	reports	report	VERB
admet-2088	1567	4	47	47	NUM
admet-2088	1567	5	(	(	PUNCT
admet-2088	1567	6	2020	2020	NUM
admet-2088	1567	7	)	)	PUNCT
admet-2088	1567	8	6517	6517	NUM
admet-2088	1567	9	-	-	SYM
admet-2088	1567	10	6529	6529	NUM
admet-2088	1567	11	,	,	PUNCT
admet-2088	1567	12	https://doi.org/10.1007/s11033020-05704-z	https://doi.org/10.1007/s11033020-05704-z	PROPN
admet-2088	1567	13	.	.	PUNCT
admet-2088	1568	1	[	[	X
admet-2088	1568	2	214	214	NUM
admet-2088	1568	3	]	]	X
admet-2088	1568	4	s.h	s.h	PROPN
admet-2088	1568	5	.	.	PROPN
admet-2088	1568	6	chermahini	chermahini	PROPN
admet-2088	1568	7	,	,	PUNCT
admet-2088	1568	8	r.b	r.b	PROPN
admet-2088	1568	9	.	.	PROPN
admet-2088	1568	10	najafi	najafi	PROPN
admet-2088	1568	11	.	.	PUNCT
admet-2088	1568	12	niosome	niosome	PROPN
admet-2088	1568	13	encapsulated	encapsulate	VERB
admet-2088	1568	14	fluorouracil	fluorouracil	NOUN
admet-2088	1568	15	as	as	ADP
admet-2088	1568	16	drug	drug	NOUN
admet-2088	1568	17	delivery	delivery	NOUN
admet-2088	1568	18	system	system	NOUN
admet-2088	1568	19	to	to	PART
admet-2088	1568	20	basalcell	basalcell	VERB
admet-2088	1568	21	skin	skin	NOUN
admet-2088	1568	22	cancer	cancer	NOUN
admet-2088	1568	23	.	.	PUNCT
admet-2088	1569	1	journal	journal	PROPN
admet-2088	1569	2	of	of	ADP
admet-2088	1569	3	nanoscience	nanoscience	PROPN
admet-2088	1569	4	and	and	CCONJ
admet-2088	1569	5	nanomedicine	nanomedicine	NOUN
admet-2088	1569	6	3	3	NUM
admet-2088	1569	7	(	(	PUNCT
admet-2088	1569	8	2019	2019	NUM
admet-2088	1569	9	)	)	PUNCT
admet-2088	1569	10	1	1	NUM
admet-2088	1569	11	-	-	SYM
admet-2088	1569	12	4	4	NUM
admet-2088	1569	13	.	.	PUNCT
admet-2088	1569	14	https://www.pulsus.com/scholarly-articles/niosome-encapsulated-fluorouracil-as-drug-deliverysystem-to-basalcell-skin-cancer-5149.html	https://www.pulsus.com/scholarly-articles/niosome-encapsulated-fluorouracil-as-drug-deliverysystem-to-basalcell-skin-cancer-5149.html	PROPN
admet-2088	1569	15	.	.	PUNCT
admet-2088	1570	1	[	[	X
admet-2088	1570	2	215	215	NUM
admet-2088	1570	3	]	]	X
admet-2088	1570	4	m.c	m.c	PROPN
admet-2088	1570	5	.	.	PROPN
admet-2088	1570	6	cristiano	cristiano	PROPN
admet-2088	1570	7	,	,	PUNCT
admet-2088	1570	8	f.	f.	PROPN
admet-2088	1570	9	froiio	froiio	PROPN
admet-2088	1570	10	,	,	PUNCT
admet-2088	1570	11	r.	r.	PROPN
admet-2088	1570	12	spaccapelo	spaccapelo	PROPN
admet-2088	1570	13	,	,	PUNCT
admet-2088	1570	14	a.	a.	PROPN
admet-2088	1570	15	mancuso	mancuso	PROPN
admet-2088	1570	16	,	,	PUNCT
admet-2088	1570	17	s.p	s.p	PROPN
admet-2088	1570	18	.	.	PROPN
admet-2088	1570	19	nisticò	nisticò	PROPN
admet-2088	1570	20	,	,	PUNCT
admet-2088	1570	21	b.p	b.p	PROPN
admet-2088	1570	22	.	.	PROPN
admet-2088	1570	23	udongo	udongo	PROPN
admet-2088	1570	24	,	,	PUNCT
admet-2088	1570	25	m.	m.	NOUN
admet-2088	1570	26	fresta	fresta	PROPN
admet-2088	1570	27	,	,	PUNCT
admet-2088	1570	28	d.	d.	PROPN
admet-2088	1570	29	paolino	paolino	PROPN
admet-2088	1570	30	.	.	PUNCT
admet-2088	1570	31	sulforaphane	sulforaphane	NOUN
admet-2088	1570	32	-	-	PUNCT
admet-2088	1570	33	loaded	load	VERB
admet-2088	1570	34	ultradeformable	ultradeformable	ADJ
admet-2088	1570	35	vesicles	vesicle	NOUN
admet-2088	1570	36	as	as	ADP
admet-2088	1570	37	a	a	DET
admet-2088	1570	38	potential	potential	ADJ
admet-2088	1570	39	natural	natural	ADJ
admet-2088	1570	40	nanomedicine	nanomedicine	NOUN
admet-2088	1570	41	for	for	ADP
admet-2088	1570	42	the	the	DET
admet-2088	1570	43	treatment	treatment	NOUN
admet-2088	1570	44	of	of	ADP
admet-2088	1570	45	skin	skin	NOUN
admet-2088	1570	46	cancer	cancer	NOUN
admet-2088	1570	47	diseases	disease	NOUN
admet-2088	1570	48	.	.	PUNCT
admet-2088	1571	1	pharmaceutics	pharmaceutic	NOUN
admet-2088	1571	2	12	12	NUM
admet-2088	1571	3	(	(	PUNCT
admet-2088	1571	4	2019	2019	NUM
admet-2088	1571	5	)	)	PUNCT
admet-2088	1571	6	6	6	NUM
admet-2088	1571	7	.	.	PUNCT
admet-2088	1571	8	https://doi.org/10.3390/pharmaceutics12010006	https://doi.org/10.3390/pharmaceutics12010006	NOUN
admet-2088	1571	9	.	.	PUNCT
admet-2088	1572	1	[	[	X
admet-2088	1572	2	216	216	NUM
admet-2088	1572	3	]	]	X
admet-2088	1572	4	p.k	p.k	PROPN
admet-2088	1572	5	.	.	PROPN
admet-2088	1572	6	mukherjee	mukherjee	PROPN
admet-2088	1572	7	,	,	PUNCT
admet-2088	1572	8	r.k	r.k	PROPN
admet-2088	1572	9	.	.	PROPN
admet-2088	1572	10	harwansh	harwansh	PROPN
admet-2088	1572	11	,	,	PUNCT
admet-2088	1572	12	s.	s.	PROPN
admet-2088	1572	13	bhattacharyya	bhattacharyya	PROPN
admet-2088	1572	14	.	.	PUNCT
admet-2088	1573	1	bioavailability	bioavailability	NOUN
admet-2088	1573	2	of	of	ADP
admet-2088	1573	3	herbal	herbal	ADJ
admet-2088	1573	4	products	product	NOUN
admet-2088	1573	5	:	:	PUNCT
admet-2088	1573	6	approach	approach	NOUN
admet-2088	1573	7	toward	toward	ADP
admet-2088	1573	8	improved	improved	ADJ
admet-2088	1573	9	pharmacokinetics	pharmacokinetic	NOUN
admet-2088	1573	10	,	,	PUNCT
admet-2088	1573	11	in	in	ADP
admet-2088	1573	12	p.	p.	PROPN
admet-2088	1573	13	k.	k.	PROPN
admet-2088	1573	14	mukherjee	mukherjee	PROPN
admet-2088	1573	15	(	(	PUNCT
admet-2088	1573	16	ed	ed	NOUN
admet-2088	1573	17	.	.	PUNCT
admet-2088	1573	18	)	)	PUNCT
admet-2088	1573	19	.	.	PUNCT
admet-2088	1574	1	,	,	PUNCT
admet-2088	1574	2	evidence	evidence	NOUN
admet-2088	1574	3	-	-	PUNCT
admet-2088	1574	4	based	base	VERB
admet-2088	1574	5	validation	validation	NOUN
admet-2088	1574	6	of	of	ADP
admet-2088	1574	7	herbal	herbal	ADJ
admet-2088	1574	8	medicine	medicine	NOUN
admet-2088	1574	9	,	,	PUNCT
admet-2088	1574	10	elsevier	elsevier	PROPN
admet-2088	1574	11	,	,	PUNCT
admet-2088	1574	12	boston	boston	PROPN
admet-2088	1574	13	,	,	PUNCT
admet-2088	1574	14	2015	2015	NUM
admet-2088	1574	15	,	,	PUNCT
admet-2088	1574	16	p.	p.	NOUN
admet-2088	1574	17	217	217	NUM
admet-2088	1574	18	-	-	SYM
admet-2088	1574	19	245	245	NUM
admet-2088	1574	20	.	.	PUNCT
admet-2088	1575	1	https://doi.org/10.1016/b978-0-12-800874-4.00010-6	https://doi.org/10.1016/b978-0-12-800874-4.00010-6	NOUN
admet-2088	1575	2	.	.	PUNCT
admet-2088	1576	1	[	[	X
admet-2088	1576	2	217	217	NUM
admet-2088	1576	3	]	]	PUNCT
admet-2088	1576	4	l.	l.	PROPN
admet-2088	1576	5	yang	yang	PROPN
admet-2088	1576	6	,	,	PUNCT
admet-2088	1576	7	zheran	zheran	PROPN
admet-2088	1576	8	wang	wang	PROPN
admet-2088	1576	9	,	,	PUNCT
admet-2088	1576	10	ju	ju	PROPN
admet-2088	1576	11	wang	wang	PROPN
admet-2088	1576	12	,	,	PUNCT
admet-2088	1576	13	weihua	weihua	PROPN
admet-2088	1576	14	jiang	jiang	PROPN
admet-2088	1576	15	,	,	PUNCT
admet-2088	1576	16	xuewei	xuewei	PROPN
admet-2088	1576	17	jiang	jiang	PROPN
admet-2088	1576	18	,	,	PUNCT
admet-2088	1576	19	zhaoshi	zhaoshi	PROPN
admet-2088	1576	20	bai	bai	PROPN
admet-2088	1576	21	,	,	PUNCT
admet-2088	1576	22	yunpeng	yunpeng	PROPN
admet-2088	1576	23	he	he	PRON
admet-2088	1576	24	,	,	PUNCT
admet-2088	1576	25	jianqi	jianqi	PROPN
admet-2088	1576	26	jiang	jiang	PROPN
admet-2088	1576	27	,	,	PUNCT
admet-2088	1576	28	dongkai	dongkai	PROPN
admet-2088	1576	29	wang	wang	PROPN
admet-2088	1576	30	,	,	PUNCT
admet-2088	1576	31	li	li	PROPN
admet-2088	1576	32	yang	yang	PROPN
admet-2088	1576	33	.	.	PUNCT
admet-2088	1577	1	doxorubicin	doxorubicin	PROPN
admet-2088	1577	2	conjugated	conjugate	VERB
admet-2088	1577	3	functionalizable	functionalizable	ADJ
admet-2088	1577	4	carbon	carbon	NOUN
admet-2088	1577	5	dots	dot	NOUN
admet-2088	1577	6	for	for	ADP
admet-2088	1577	7	nucleus	nucleus	ADJ
admet-2088	1577	8	targeted	target	VERB
admet-2088	1577	9	delivery	delivery	NOUN
admet-2088	1577	10	and	and	CCONJ
admet-2088	1577	11	enhanced	enhance	VERB
admet-2088	1577	12	therapeutic	therapeutic	ADJ
admet-2088	1577	13	efficacy	efficacy	NOUN
admet-2088	1577	14	.	.	PUNCT
admet-2088	1578	1	nanoscale	nanoscale	NOUN
admet-2088	1578	2	8	8	NUM
admet-2088	1578	3	(	(	PUNCT
admet-2088	1578	4	2016	2016	NUM
admet-2088	1578	5	)	)	PUNCT
admet-2088	1578	6	6801	6801	NUM
admet-2088	1578	7	-	-	SYM
admet-2088	1578	8	6809	6809	NUM
admet-2088	1578	9	.	.	PUNCT
admet-2088	1579	1	https://doi.org/10.1039/c6nr00247a	https://doi.org/10.1039/c6nr00247a	X
admet-2088	1579	2	.	.	PUNCT
admet-2088	1580	1	[	[	X
admet-2088	1580	2	218	218	NUM
admet-2088	1580	3	]	]	PUNCT
admet-2088	1580	4	z.	z.	PROPN
admet-2088	1580	5	xu	xu	PROPN
admet-2088	1580	6	,	,	PUNCT
admet-2088	1580	7	shaojia	shaojia	PROPN
admet-2088	1580	8	zhu	zhu	PROPN
admet-2088	1580	9	,	,	PUNCT
admet-2088	1580	10	mingwei	mingwei	PROPN
admet-2088	1580	11	wang	wang	PROPN
admet-2088	1580	12	,	,	PUNCT
admet-2088	1580	13	yongjun	yongjun	PROPN
admet-2088	1580	14	li	li	PROPN
admet-2088	1580	15	,	,	PUNCT
admet-2088	1580	16	ping	ping	PROPN
admet-2088	1580	17	shi	shi	PROPN
admet-2088	1580	18	,	,	PUNCT
admet-2088	1580	19	xiaoyu	xiaoyu	PROPN
admet-2088	1580	20	huang	huang	PROPN
admet-2088	1580	21	.	.	PUNCT
admet-2088	1581	1	delivery	delivery	NOUN
admet-2088	1581	2	of	of	ADP
admet-2088	1581	3	paclitaxel	paclitaxel	PROPN
admet-2088	1581	4	using	use	VERB
admet-2088	1581	5	pegylated	pegylate	VERB
admet-2088	1581	6	graphene	graphene	NOUN
admet-2088	1581	7	oxide	oxide	NOUN
admet-2088	1581	8	as	as	ADP
admet-2088	1581	9	a	a	DET
admet-2088	1581	10	nanocarrier	nanocarrier	NOUN
admet-2088	1581	11	.	.	PUNCT
admet-2088	1582	1	acs	acs	PROPN
admet-2088	1582	2	applied	apply	VERB
admet-2088	1582	3	materials	material	NOUN
admet-2088	1582	4	&	&	CCONJ
admet-2088	1582	5	interfaces	interface	NOUN
admet-2088	1582	6	7	7	NUM
admet-2088	1582	7	(	(	PUNCT
admet-2088	1582	8	2015	2015	NUM
admet-2088	1582	9	)	)	PUNCT
admet-2088	1582	10	1355	1355	NUM
admet-2088	1582	11	-	-	SYM
admet-2088	1582	12	1363	1363	NUM
admet-2088	1582	13	.	.	PUNCT
admet-2088	1583	1	https://doi.org/10.1021/am507798d	https://doi.org/10.1021/am507798d	X
admet-2088	1583	2	.	.	PUNCT
admet-2088	1584	1	[	[	X
admet-2088	1584	2	219	219	NUM
admet-2088	1584	3	]	]	X
admet-2088	1584	4	w.	w.	PROPN
admet-2088	1584	5	mehnert	mehnert	PROPN
admet-2088	1584	6	,	,	PUNCT
admet-2088	1584	7	k.	k.	PROPN
admet-2088	1584	8	m¨ader	m¨ader	PROPN
admet-2088	1584	9	.	.	PUNCT
admet-2088	1584	10	solid	solid	ADJ
admet-2088	1584	11	lipid	lipid	ADJ
admet-2088	1584	12	nanoparticles	nanoparticle	NOUN
admet-2088	1584	13	:	:	PUNCT
admet-2088	1584	14	production	production	NOUN
admet-2088	1584	15	,	,	PUNCT
admet-2088	1584	16	characterization	characterization	NOUN
admet-2088	1584	17	and	and	CCONJ
admet-2088	1584	18	applications	application	NOUN
admet-2088	1584	19	.	.	PUNCT
admet-2088	1585	1	advanced	advanced	ADJ
admet-2088	1585	2	drug	drug	NOUN
admet-2088	1585	3	delivery	delivery	NOUN
admet-2088	1585	4	reviews	review	VERB
admet-2088	1585	5	64	64	NUM
admet-2088	1585	6	(	(	PUNCT
admet-2088	1585	7	2012	2012	NUM
admet-2088	1585	8	)	)	PUNCT
admet-2088	1585	9	83	83	NUM
admet-2088	1585	10	-	-	SYM
admet-2088	1585	11	101	101	NUM
admet-2088	1585	12	,	,	PUNCT
admet-2088	1585	13	https://doi.org/10.1016/j.addr.2012.09.021	https://doi.org/10.1016/j.addr.2012.09.021	NUM
admet-2088	1585	14	.	.	PUNCT
admet-2088	1586	1	[	[	X
admet-2088	1586	2	220	220	NUM
admet-2088	1586	3	]	]	PUNCT
admet-2088	1586	4	a.	a.	NOUN
admet-2088	1586	5	abak	abak	NOUN
admet-2088	1586	6	,	,	PUNCT
admet-2088	1586	7	a.	a.	NOUN
admet-2088	1586	8	abhari	abhari	NOUN
admet-2088	1586	9	,	,	PUNCT
admet-2088	1586	10	s.	s.	PROPN
admet-2088	1586	11	rahimzadeh	rahimzadeh	PROPN
admet-2088	1586	12	.	.	PUNCT
admet-2088	1587	1	exosomes	exosome	NOUN
admet-2088	1587	2	in	in	ADP
admet-2088	1587	3	cancer	cancer	NOUN
admet-2088	1587	4	:	:	PUNCT
admet-2088	1587	5	small	small	ADJ
admet-2088	1587	6	vesicular	vesicular	ADJ
admet-2088	1587	7	transporters	transporter	NOUN
admet-2088	1587	8	for	for	ADP
admet-2088	1587	9	cancer	cancer	NOUN
admet-2088	1587	10	progression	progression	NOUN
admet-2088	1587	11	and	and	CCONJ
admet-2088	1587	12	metastasis	metastasis	NOUN
admet-2088	1587	13	,	,	PUNCT
admet-2088	1587	14	biomarkers	biomarker	NOUN
admet-2088	1587	15	in	in	ADP
admet-2088	1587	16	cancer	cancer	NOUN
admet-2088	1587	17	therapeutics	therapeutic	NOUN
admet-2088	1587	18	.	.	PUNCT
admet-2088	1588	1	peer	peer	NOUN
admet-2088	1588	2	reviewed	review	VERB
admet-2088	1588	3	journal	journal	NOUN
admet-2088	1588	4	6	6	NUM
admet-2088	1588	5	(	(	PUNCT
admet-2088	1588	6	2018	2018	NUM
admet-2088	1588	7	)	)	PUNCT
admet-2088	1588	8	e4763	e4763	NOUN
admet-2088	1588	9	.	.	PUNCT
admet-2088	1589	1	https://doi.org/10.7717/peerj.4763	https://doi.org/10.7717/peerj.4763	PROPN
admet-2088	1589	2	.	.	PUNCT
admet-2088	1590	1	[	[	X
admet-2088	1590	2	221	221	NUM
admet-2088	1590	3	]	]	X
admet-2088	1590	4	n.	n.	NOUN
admet-2088	1590	5	jabbari	jabbari	NOUN
admet-2088	1590	6	,	,	PUNCT
admet-2088	1590	7	m.	m.	NOUN
admet-2088	1590	8	karimipour	karimipour	PROPN
admet-2088	1590	9	,	,	PUNCT
admet-2088	1590	10	m.	m.	NOUN
admet-2088	1590	11	khaksar	khaksar	PROPN
admet-2088	1590	12	,	,	PUNCT
admet-2088	1590	13	e.	e.	PROPN
admet-2088	1590	14	akbariazar	akbariazar	PROPN
admet-2088	1590	15	,	,	PUNCT
admet-2088	1590	16	m.	m.	NOUN
admet-2088	1590	17	heidarzadeh	heidarzadeh	PROPN
admet-2088	1590	18	,	,	PUNCT
admet-2088	1590	19	b.	b.	PROPN
admet-2088	1590	20	mojarad	mojarad	PROPN
admet-2088	1590	21	,	,	PUNCT
admet-2088	1590	22	h.	h.	PROPN
admet-2088	1590	23	aftab	aftab	PROPN
admet-2088	1590	24	,	,	PUNCT
admet-2088	1590	25	r.	r.	PROPN
admet-2088	1590	26	rahbarghazi	rahbarghazi	PROPN
admet-2088	1590	27	,	,	PUNCT
admet-2088	1590	28	j.	j.	PROPN
admet-2088	1590	29	rezaie	rezaie	PROPN
admet-2088	1590	30	.	.	PUNCT
admet-2088	1591	1	tumor	tumor	NOUN
admet-2088	1591	2	-	-	PUNCT
admet-2088	1591	3	derived	derive	VERB
admet-2088	1591	4	extracellular	extracellular	ADJ
admet-2088	1591	5	vesicles	vesicle	NOUN
admet-2088	1591	6	:	:	PUNCT
admet-2088	1591	7	insights	insight	NOUN
admet-2088	1591	8	into	into	ADP
admet-2088	1591	9	bystander	bystander	NOUN
admet-2088	1591	10	effects	effect	NOUN
admet-2088	1591	11	of	of	ADP
admet-2088	1591	12	https://doi.org/10.5599/admet.2088	https://doi.org/10.5599/admet.2088	PRON
admet-2088	1591	13	https://doi.org/10.1016/j.drudis.2020.09.026	https://doi.org/10.1016/j.drudis.2020.09.026	PROPN
admet-2088	1591	14	https://doi.org/10.1016/j.jconrel.2023.01.034	https://doi.org/10.1016/j.jconrel.2023.01.034	PROPN
admet-2088	1591	15	https://doi.org/10.1016/j.carbpol.2019.115143	https://doi.org/10.1016/j.carbpol.2019.115143	NOUN
admet-2088	1591	16	https://doi.org/10.3390/pharmaceutics11040163	https://doi.org/10.3390/pharmaceutics11040163	NOUN
admet-2088	1591	17	https://doi.org/10.3390/polym11091515	https://doi.org/10.3390/polym11091515	NOUN
admet-2088	1591	18	https://doi.org/10.1016/j.biomaterials.2018.10.011	https://doi.org/10.1016/j.biomaterials.2018.10.011	PROPN
admet-2088	1591	19	https://doi.org/10.1515/abm-2018-0002	https://doi.org/10.1515/abm-2018-0002	NOUN
admet-2088	1591	20	https://doi.org/10.1007/s11033-020-05704-z	https://doi.org/10.1007/s11033-020-05704-z	PROPN
admet-2088	1591	21	https://doi.org/10.1007/s11033-020-05704-z	https://doi.org/10.1007/s11033-020-05704-z	PROPN
admet-2088	1591	22	https://www.pulsus.com/scholarly-articles/niosome-encapsulated-fluorouracil-as-drug-delivery-system-to-basalcell-skin-cancer-5149.html	https://www.pulsus.com/scholarly-articles/niosome-encapsulated-fluorouracil-as-drug-delivery-system-to-basalcell-skin-cancer-5149.html	ADV
admet-2088	1591	23	https://www.pulsus.com/scholarly-articles/niosome-encapsulated-fluorouracil-as-drug-delivery-system-to-basalcell-skin-cancer-5149.html	https://www.pulsus.com/scholarly-articles/niosome-encapsulated-fluorouracil-as-drug-delivery-system-to-basalcell-skin-cancer-5149.html	ADJ
admet-2088	1591	24	https://doi.org/10.3390/pharmaceutics12010006	https://doi.org/10.3390/pharmaceutics12010006	NOUN
admet-2088	1591	25	https://doi.org/10.1016/b978-0-12-800874-4.00010-6	https://doi.org/10.1016/b978-0-12-800874-4.00010-6	PROPN
admet-2088	1591	26	https://doi.org/10.1039/c6nr00247a	https://doi.org/10.1039/c6nr00247a	X
admet-2088	1591	27	https://doi.org/10.1021/am507798d	https://doi.org/10.1021/am507798d	VERB
admet-2088	1591	28	https://doi.org/10.1016/j.addr.2012.09.021	https://doi.org/10.1016/j.addr.2012.09.021	NUM
admet-2088	1591	29	https://doi.org/10.7717/peerj.4763	https://doi.org/10.7717/peerj.4763	ADJ
admet-2088	1591	30	m.	m.	NOUN
admet-2088	1591	31	kulkarni	kulkarni	PROPN
admet-2088	1591	32	et	et	PROPN
admet-2088	1591	33	al	al	PROPN
admet-2088	1591	34	.	.	PROPN
admet-2088	1591	35	admet	admet	PROPN
admet-2088	1591	36	&	&	CCONJ
admet-2088	1591	37	dmpk	dmpk	PROPN
admet-2088	1591	38	12(1	12(1	PROPN
admet-2088	1591	39	)	)	PUNCT
admet-2088	1591	40	(	(	PUNCT
admet-2088	1591	41	2024	2024	NUM
admet-2088	1591	42	)	)	PUNCT
admet-2088	1591	43	107	107	NUM
admet-2088	1591	44	-	-	SYM
admet-2088	1591	45	150	150	NUM
admet-2088	1591	46	150	150	NUM
admet-2088	1591	47	exosomes	exosome	NOUN
admet-2088	1591	48	after	after	ADP
admet-2088	1591	49	irradiation	irradiation	NOUN
admet-2088	1591	50	.	.	PUNCT
admet-2088	1592	1	lasers	laser	NOUN
admet-2088	1592	2	in	in	ADP
admet-2088	1592	3	medical	medical	ADJ
admet-2088	1592	4	science	science	NOUN
admet-2088	1592	5	35	35	NUM
admet-2088	1592	6	(	(	PUNCT
admet-2088	1592	7	2020	2020	NUM
admet-2088	1592	8	)	)	PUNCT
admet-2088	1592	9	531	531	NUM
admet-2088	1592	10	-	-	SYM
admet-2088	1592	11	545	545	NUM
admet-2088	1592	12	.	.	PUNCT
admet-2088	1593	1	https://doi.org/10.1007/s10103-019-02880-8	https://doi.org/10.1007/s10103-019-02880-8	PROPN
admet-2088	1593	2	.	.	PUNCT
admet-2088	1594	1	[	[	X
admet-2088	1594	2	222	222	NUM
admet-2088	1594	3	]	]	X
admet-2088	1594	4	c.	c.	PROPN
admet-2088	1594	5	thery	thery	PROPN
admet-2088	1594	6	,	,	PUNCT
admet-2088	1594	7	m.	m.	NOUN
admet-2088	1594	8	ostrowski	ostrowski	PROPN
admet-2088	1594	9	,	,	PUNCT
admet-2088	1594	10	e.	e.	PROPN
admet-2088	1594	11	segura	segura	PROPN
admet-2088	1594	12	.	.	PUNCT
admet-2088	1594	13	membrane	membrane	NOUN
admet-2088	1594	14	vesicles	vesicle	NOUN
admet-2088	1594	15	as	as	ADP
admet-2088	1594	16	conveyors	conveyor	NOUN
admet-2088	1594	17	of	of	ADP
admet-2088	1594	18	immune	immune	ADJ
admet-2088	1594	19	responses	response	NOUN
admet-2088	1594	20	.	.	PUNCT
admet-2088	1595	1	nature	nature	NOUN
admet-2088	1595	2	reviews	review	VERB
admet-2088	1595	3	immunology	immunology	NOUN
admet-2088	1595	4	9	9	NUM
admet-2088	1595	5	(	(	PUNCT
admet-2088	1595	6	2009	2009	NUM
admet-2088	1595	7	)	)	PUNCT
admet-2088	1595	8	581	581	NUM
admet-2088	1595	9	-	-	SYM
admet-2088	1595	10	593	593	NUM
admet-2088	1595	11	.	.	PUNCT
admet-2088	1596	1	https://doi.org/10.1038/nri2567	https://doi.org/10.1038/nri2567	VERB
admet-2088	1596	2	.	.	PUNCT
admet-2088	1597	1	[	[	X
admet-2088	1597	2	223	223	NUM
admet-2088	1597	3	]	]	PUNCT
admet-2088	1597	4	t.	t.	PROPN
admet-2088	1597	5	huyan	huyan	PROPN
admet-2088	1597	6	,	,	PUNCT
admet-2088	1597	7	h.	h.	PROPN
admet-2088	1597	8	li	li	PROPN
admet-2088	1597	9	,	,	PUNCT
admet-2088	1597	10	h.	h.	PROPN
admet-2088	1597	11	peng	peng	PROPN
admet-2088	1597	12	,	,	PUNCT
admet-2088	1597	13	j.	j.	PROPN
admet-2088	1597	14	chen	chen	PROPN
admet-2088	1597	15	,	,	PUNCT
admet-2088	1597	16	r.	r.	PROPN
admet-2088	1597	17	yang	yang	PROPN
admet-2088	1597	18	,	,	PUNCT
admet-2088	1597	19	w.	w.	PROPN
admet-2088	1597	20	zhang	zhang	PROPN
admet-2088	1597	21	,	,	PUNCT
admet-2088	1597	22	q.	q.	PROPN
admet-2088	1597	23	li	li	PROPN
admet-2088	1597	24	.	.	PROPN
admet-2088	1597	25	extracellular	extracellular	ADJ
admet-2088	1597	26	vesicles	vesicle	NOUN
admet-2088	1597	27	–	–	PUNCT
admet-2088	1597	28	advanced	advance	VERB
admet-2088	1597	29	nanocarriers	nanocarrier	NOUN
admet-2088	1597	30	in	in	ADP
admet-2088	1597	31	cancer	cancer	NOUN
admet-2088	1597	32	therapy	therapy	NOUN
admet-2088	1597	33	:	:	PUNCT
admet-2088	1597	34	progress	progress	NOUN
admet-2088	1597	35	and	and	CCONJ
admet-2088	1597	36	achievements	achievement	NOUN
admet-2088	1597	37	.	.	PUNCT
admet-2088	1598	1	international	international	ADJ
admet-2088	1598	2	journal	journal	PROPN
admet-2088	1598	3	nanomedicine	nanomedicine	PROPN
admet-2088	1598	4	15	15	NUM
admet-2088	1598	5	(	(	PUNCT
admet-2088	1598	6	2020	2020	NUM
admet-2088	1598	7	)	)	PUNCT
admet-2088	1598	8	6485	6485	NUM
admet-2088	1598	9	-	-	SYM
admet-2088	1598	10	502	502	NUM
admet-2088	1598	11	.	.	PUNCT
admet-2088	1598	12	https://doi.org/10.2147/ijn.s238099	https://doi.org/10.2147/ijn.s238099	PROPN
admet-2088	1598	13	.	.	PUNCT
admet-2088	1599	1	[	[	X
admet-2088	1599	2	224	224	NUM
admet-2088	1599	3	]	]	PUNCT
admet-2088	1599	4	m.	m.	PROPN
admet-2088	1599	5	millard	millard	PROPN
admet-2088	1599	6	,	,	PUNCT
admet-2088	1599	7	i.	i.	NOUN
admet-2088	1599	8	yakavets	yakavet	NOUN
admet-2088	1599	9	,	,	PUNCT
admet-2088	1599	10	m.	m.	NOUN
admet-2088	1599	11	piffoux	piffoux	NOUN
admet-2088	1599	12	,	,	PUNCT
admet-2088	1599	13	a.	a.	NOUN
admet-2088	1599	14	brun	brun	PROPN
admet-2088	1599	15	,	,	PUNCT
admet-2088	1599	16	f.	f.	PROPN
admet-2088	1599	17	gazeau	gazeau	PROPN
admet-2088	1599	18	,	,	PUNCT
admet-2088	1599	19	j.-m	j.-m	PROPN
admet-2088	1599	20	.	.	PUNCT
admet-2088	1600	1	guigner	guigner	PROPN
admet-2088	1600	2	,	,	PUNCT
admet-2088	1600	3	j.	j.	PROPN
admet-2088	1600	4	jasniewski	jasniewski	PROPN
admet-2088	1600	5	,	,	PUNCT
admet-2088	1600	6	h.-p	h.-p	PROPN
admet-2088	1600	7	.	.	PUNCT
admet-2088	1601	1	lassalle	lassalle	PROPN
admet-2088	1601	2	,	,	PUNCT
admet-2088	1601	3	c.	c.	PROPN
admet-2088	1601	4	wilhelm	wilhelm	PROPN
admet-2088	1601	5	,	,	PUNCT
admet-2088	1601	6	l.	l.	PROPN
admet-2088	1601	7	bezdetnaya	bezdetnaya	PROPN
admet-2088	1601	8	.	.	PUNCT
admet-2088	1601	9	mthpc	mthpc	NOUN
admet-2088	1601	10	-	-	PUNCT
admet-2088	1601	11	loaded	load	VERB
admet-2088	1601	12	extracellular	extracellular	ADJ
admet-2088	1601	13	vesicles	vesicle	NOUN
admet-2088	1601	14	outperform	outperform	VERB
admet-2088	1601	15	liposomal	liposomal	ADJ
admet-2088	1601	16	and	and	CCONJ
admet-2088	1601	17	free	free	ADJ
admet-2088	1601	18	mthpc	mthpc	NOUN
admet-2088	1601	19	formulations	formulation	NOUN
admet-2088	1601	20	by	by	ADP
admet-2088	1601	21	an	an	DET
admet-2088	1601	22	increased	increase	VERB
admet-2088	1601	23	stability	stability	NOUN
admet-2088	1601	24	,	,	PUNCT
admet-2088	1601	25	drug	drug	NOUN
admet-2088	1601	26	delivery	delivery	NOUN
admet-2088	1601	27	efficiency	efficiency	NOUN
admet-2088	1601	28	and	and	CCONJ
admet-2088	1601	29	cytotoxic	cytotoxic	ADJ
admet-2088	1601	30	effect	effect	NOUN
admet-2088	1601	31	in	in	ADP
admet-2088	1601	32	tridimensional	tridimensional	ADJ
admet-2088	1601	33	model	model	NOUN
admet-2088	1601	34	of	of	ADP
admet-2088	1601	35	tumors	tumor	NOUN
admet-2088	1601	36	.	.	PUNCT
admet-2088	1602	1	drug	drug	NOUN
admet-2088	1602	2	delivery	delivery	NOUN
admet-2088	1602	3	25	25	NUM
admet-2088	1602	4	(	(	PUNCT
admet-2088	1602	5	2018	2018	NUM
admet-2088	1602	6	)	)	PUNCT
admet-2088	1602	7	1790	1790	NUM
admet-2088	1602	8	-	-	SYM
admet-2088	1602	9	1801	1801	NUM
admet-2088	1602	10	.	.	PUNCT
admet-2088	1603	1	https://doi.org/10.1080/10717544.2018.1513609	https://doi.org/10.1080/10717544.2018.1513609	NOUN
admet-2088	1603	2	.	.	PUNCT
admet-2088	1604	1	[	[	X
admet-2088	1604	2	225	225	NUM
admet-2088	1604	3	]	]	PUNCT
admet-2088	1604	4	m.	m.	NOUN
admet-2088	1604	5	mathieu	mathieu	PROPN
admet-2088	1604	6	,	,	PUNCT
admet-2088	1604	7	l.	l.	PROPN
admet-2088	1604	8	martin	martin	PROPN
admet-2088	1604	9	-	-	PUNCT
admet-2088	1604	10	jaular	jaular	ADJ
admet-2088	1604	11	,	,	PUNCT
admet-2088	1604	12	g.	g.	PROPN
admet-2088	1604	13	lavieu	lavieu	PROPN
admet-2088	1604	14	,	,	PUNCT
admet-2088	1604	15	c.	c.	PROPN
admet-2088	1604	16	théry	théry	PROPN
admet-2088	1604	17	.	.	PUNCT
admet-2088	1605	1	specificities	specificity	NOUN
admet-2088	1605	2	of	of	ADP
admet-2088	1605	3	secretion	secretion	NOUN
admet-2088	1605	4	and	and	CCONJ
admet-2088	1605	5	uptake	uptake	NOUN
admet-2088	1605	6	of	of	ADP
admet-2088	1605	7	exosomes	exosome	NOUN
admet-2088	1605	8	and	and	CCONJ
admet-2088	1605	9	other	other	ADJ
admet-2088	1605	10	extracellular	extracellular	ADJ
admet-2088	1605	11	vesicles	vesicle	NOUN
admet-2088	1605	12	for	for	ADP
admet-2088	1605	13	cell	cell	NOUN
admet-2088	1605	14	-	-	PUNCT
admet-2088	1605	15	to	to	ADP
admet-2088	1605	16	-	-	PUNCT
admet-2088	1605	17	cell	cell	NOUN
admet-2088	1605	18	communication	communication	NOUN
admet-2088	1605	19	.	.	PUNCT
admet-2088	1606	1	nature	nature	NOUN
admet-2088	1606	2	cell	cell	NOUN
admet-2088	1606	3	biology	biology	NOUN
admet-2088	1606	4	21	21	NUM
admet-2088	1606	5	(	(	PUNCT
admet-2088	1606	6	2019	2019	NUM
admet-2088	1606	7	)	)	PUNCT
admet-2088	1606	8	9	9	NUM
admet-2088	1606	9	-	-	SYM
admet-2088	1606	10	17	17	NUM
admet-2088	1606	11	.	.	PUNCT
admet-2088	1606	12	https://doi.org/10.1038/s41556-018-0250-9	https://doi.org/10.1038/s41556-018-0250-9	NUM
admet-2088	1606	13	.	.	PUNCT
admet-2088	1607	1	[	[	X
admet-2088	1607	2	226	226	NUM
admet-2088	1607	3	]	]	X
admet-2088	1607	4	i.k	i.k	PROPN
admet-2088	1607	5	.	.	PROPN
admet-2088	1607	6	herrmann	herrmann	PROPN
admet-2088	1607	7	,	,	PUNCT
admet-2088	1607	8	m.j.a	m.j.a	PROPN
admet-2088	1607	9	.	.	PUNCT
admet-2088	1607	10	wood	wood	PROPN
admet-2088	1607	11	,	,	PUNCT
admet-2088	1607	12	g.	g.	PROPN
admet-2088	1607	13	fuhrmann	fuhrmann	PROPN
admet-2088	1607	14	.	.	PUNCT
admet-2088	1608	1	extracellular	extracellular	ADJ
admet-2088	1608	2	vesicles	vesicle	NOUN
admet-2088	1608	3	as	as	ADP
admet-2088	1608	4	a	a	DET
admet-2088	1608	5	next	next	ADJ
admet-2088	1608	6	generation	generation	NOUN
admet-2088	1608	7	drug	drug	NOUN
admet-2088	1608	8	delivery	delivery	NOUN
admet-2088	1608	9	platform	platform	NOUN
admet-2088	1608	10	.	.	PUNCT
admet-2088	1609	1	nature	nature	PROPN
admet-2088	1609	2	nanotechnology	nanotechnology	PROPN
admet-2088	1609	3	16	16	NUM
admet-2088	1609	4	(	(	PUNCT
admet-2088	1609	5	2021	2021	NUM
admet-2088	1609	6	)	)	PUNCT
admet-2088	1609	7	748	748	NUM
admet-2088	1609	8	-	-	SYM
admet-2088	1609	9	759	759	NUM
admet-2088	1609	10	.	.	PUNCT
admet-2088	1610	1	https://doi.org/10.1016/j.biopha.2022.113480	https://doi.org/10.1016/j.biopha.2022.113480	NOUN
admet-2088	1610	2	.	.	PUNCT
admet-2088	1611	1	[	[	X
admet-2088	1611	2	227	227	NUM
admet-2088	1611	3	]	]	SYM
admet-2088	1611	4	m.j	m.j	PROPN
admet-2088	1611	5	.	.	PROPN
admet-2088	1611	6	haney	haney	PROPN
admet-2088	1611	7	,	,	PUNCT
admet-2088	1611	8	n.l	n.l	PROPN
admet-2088	1611	9	.	.	PROPN
admet-2088	1611	10	klyachko	klyachko	PROPN
admet-2088	1611	11	,	,	PUNCT
admet-2088	1611	12	y.	y.	PROPN
admet-2088	1611	13	zhao	zhao	PROPN
admet-2088	1611	14	,	,	PUNCT
admet-2088	1611	15	r.	r.	PROPN
admet-2088	1611	16	gupta	gupta	PROPN
admet-2088	1611	17	,	,	PUNCT
admet-2088	1611	18	e.g.	e.g.	ADV
admet-2088	1611	19	plotnikova	plotnikova	VERB
admet-2088	1611	20	,	,	PUNCT
admet-2088	1611	21	z.	z.	PROPN
admet-2088	1611	22	he	he	PRON
admet-2088	1611	23	,	,	PUNCT
admet-2088	1611	24	t.	t.	PROPN
admet-2088	1611	25	patel	patel	PROPN
admet-2088	1611	26	,	,	PUNCT
admet-2088	1611	27	a.	a.	PROPN
admet-2088	1611	28	piroyan	piroyan	PROPN
admet-2088	1611	29	,	,	PUNCT
admet-2088	1611	30	m.	m.	NOUN
admet-2088	1611	31	sokolsky	sokolsky	NOUN
admet-2088	1611	32	,	,	PUNCT
admet-2088	1611	33	a.v	a.v	PROPN
admet-2088	1611	34	.	.	PROPN
admet-2088	1611	35	kabanov	kabanov	PROPN
admet-2088	1611	36	,	,	PUNCT
admet-2088	1611	37	e.v	e.v	PROPN
admet-2088	1611	38	.	.	PUNCT
admet-2088	1611	39	batrakova	batrakova	PROPN
admet-2088	1611	40	.	.	PUNCT
admet-2088	1612	1	exosomes	exosome	NOUN
admet-2088	1612	2	as	as	ADP
admet-2088	1612	3	drug	drug	NOUN
admet-2088	1612	4	delivery	delivery	NOUN
admet-2088	1612	5	vehicles	vehicle	NOUN
admet-2088	1612	6	for	for	ADP
admet-2088	1612	7	parkinson	parkinson	NOUN
admet-2088	1612	8	’s	’s	PART
admet-2088	1612	9	disease	disease	NOUN
admet-2088	1612	10	therapy	therapy	NOUN
admet-2088	1612	11	.	.	PUNCT
admet-2088	1613	1	journal	journal	PROPN
admet-2088	1613	2	of	of	ADP
admet-2088	1613	3	controlled	control	VERB
admet-2088	1613	4	release	release	NOUN
admet-2088	1613	5	207	207	NUM
admet-2088	1613	6	(	(	PUNCT
admet-2088	1613	7	2015	2015	NUM
admet-2088	1613	8	)	)	PUNCT
admet-2088	1613	9	18	18	NUM
admet-2088	1613	10	-	-	SYM
admet-2088	1613	11	30	30	NUM
admet-2088	1613	12	.	.	PUNCT
admet-2088	1614	1	https://doi.org/10.1016/j.jconrel.2015.03.033	https://doi.org/10.1016/j.jconrel.2015.03.033	NOUN
admet-2088	1614	2	.	.	PUNCT
admet-2088	1615	1	[	[	X
admet-2088	1615	2	228	228	NUM
admet-2088	1615	3	]	]	X
admet-2088	1615	4	m.s	m.s	PROPN
admet-2088	1615	5	.	.	PUNCT
admet-2088	1615	6	kim	kim	PROPN
admet-2088	1615	7	,	,	PUNCT
admet-2088	1615	8	m.j	m.j	PROPN
admet-2088	1615	9	.	.	PROPN
admet-2088	1615	10	haney	haney	PROPN
admet-2088	1615	11	,	,	PUNCT
admet-2088	1615	12	y.	y.	PROPN
admet-2088	1615	13	zhao	zhao	PROPN
admet-2088	1615	14	,	,	PUNCT
admet-2088	1615	15	v.	v.	PROPN
admet-2088	1615	16	mahajan	mahajan	PROPN
admet-2088	1615	17	,	,	PUNCT
admet-2088	1615	18	i.	i.	PROPN
admet-2088	1615	19	deygen	deygen	PROPN
admet-2088	1615	20	,	,	PUNCT
admet-2088	1615	21	n.l	n.l	PROPN
admet-2088	1615	22	.	.	PROPN
admet-2088	1615	23	klyachko	klyachko	PROPN
admet-2088	1615	24	,	,	PUNCT
admet-2088	1615	25	e.	e.	PROPN
admet-2088	1615	26	inskoe	inskoe	PROPN
admet-2088	1615	27	,	,	PUNCT
admet-2088	1615	28	a.	a.	PROPN
admet-2088	1615	29	piroyan	piroyan	PROPN
admet-2088	1615	30	,	,	PUNCT
admet-2088	1615	31	m.	m.	NOUN
admet-2088	1615	32	sokolsky	sokolsky	NOUN
admet-2088	1615	33	,	,	PUNCT
admet-2088	1615	34	o.	o.	PROPN
admet-2088	1615	35	okolie	okolie	PROPN
admet-2088	1615	36	,	,	PUNCT
admet-2088	1615	37	s.d	s.d	PROPN
admet-2088	1615	38	.	.	PROPN
admet-2088	1615	39	hingtgen	hingtgen	PROPN
admet-2088	1615	40	,	,	PUNCT
admet-2088	1615	41	a.v	a.v	PROPN
admet-2088	1615	42	.	.	PROPN
admet-2088	1615	43	kabanov	kabanov	PROPN
admet-2088	1615	44	,	,	PUNCT
admet-2088	1615	45	e.v	e.v	PROPN
admet-2088	1615	46	.	.	PROPN
admet-2088	1615	47	batrakova	batrakova	PROPN
admet-2088	1615	48	.	.	PUNCT
admet-2088	1616	1	development	development	NOUN
admet-2088	1616	2	of	of	ADP
admet-2088	1616	3	exosomeencapsulated	exosomeencapsulate	VERB
admet-2088	1616	4	paclitaxel	paclitaxel	PROPN
admet-2088	1616	5	to	to	PART
admet-2088	1616	6	overcome	overcome	VERB
admet-2088	1616	7	mdr	mdr	PROPN
admet-2088	1616	8	in	in	ADP
admet-2088	1616	9	cancer	cancer	NOUN
admet-2088	1616	10	cells	cell	NOUN
admet-2088	1616	11	.	.	PUNCT
admet-2088	1617	1	nanomedicine	nanomedicine	NOUN
admet-2088	1617	2	:	:	PUNCT
admet-2088	1617	3	nanotechnology	nanotechnology	NOUN
admet-2088	1617	4	,	,	PUNCT
admet-2088	1617	5	biology	biology	NOUN
admet-2088	1617	6	and	and	CCONJ
admet-2088	1617	7	medicine	medicine	NOUN
admet-2088	1617	8	12	12	NUM
admet-2088	1617	9	(	(	PUNCT
admet-2088	1617	10	2016	2016	NUM
admet-2088	1617	11	)	)	PUNCT
admet-2088	1617	12	655	655	NUM
admet-2088	1617	13	-	-	PUNCT
admet-2088	1617	14	664	664	NUM
admet-2088	1617	15	.	.	PUNCT
admet-2088	1617	16	https://doi.org/10.1016/j.nano.2015.10.012	https://doi.org/10.1016/j.nano.2015.10.012	NUM
admet-2088	1617	17	.	.	PUNCT
admet-2088	1618	1	[	[	X
admet-2088	1618	2	229	229	NUM
admet-2088	1618	3	]	]	PUNCT
admet-2088	1618	4	t.	t.	PROPN
admet-2088	1618	5	feng	feng	PROPN
admet-2088	1618	6	,	,	PUNCT
admet-2088	1618	7	z.	z.	PROPN
admet-2088	1618	8	tang	tang	PROPN
admet-2088	1618	9	,	,	PUNCT
admet-2088	1618	10	j.	j.	PROPN
admet-2088	1618	11	karges	karges	PROPN
admet-2088	1618	12	,	,	PUNCT
admet-2088	1618	13	j.	j.	PROPN
admet-2088	1618	14	shen	shen	PROPN
admet-2088	1618	15	,	,	PUNCT
admet-2088	1618	16	c.	c.	PROPN
admet-2088	1618	17	jin	jin	PROPN
admet-2088	1618	18	,	,	PUNCT
admet-2088	1618	19	y.	y.	PROPN
admet-2088	1618	20	chen	chen	PROPN
admet-2088	1618	21	,	,	PUNCT
admet-2088	1618	22	y.	y.	PROPN
admet-2088	1618	23	pan	pan	PROPN
admet-2088	1618	24	,	,	PUNCT
admet-2088	1618	25	y.	y.	PROPN
admet-2088	1618	26	he	he	PRON
admet-2088	1618	27	,	,	PUNCT
admet-2088	1618	28	l.	l.	PROPN
admet-2088	1618	29	ji	ji	PROPN
admet-2088	1618	30	,	,	PUNCT
admet-2088	1618	31	h.	h.	PROPN
admet-2088	1618	32	chao	chao	PROPN
admet-2088	1618	33	.	.	PUNCT
admet-2088	1619	1	exosome	exosome	PROPN
admet-2088	1619	2	camouflaged	camouflage	VERB
admet-2088	1619	3	coordination	coordination	NOUN
admet-2088	1619	4	-	-	PUNCT
admet-2088	1619	5	assembled	assemble	VERB
admet-2088	1619	6	iridium(iii	iridium(iii	NOUN
admet-2088	1619	7	)	)	PUNCT
admet-2088	1619	8	photosensitizers	photosensitizer	NOUN
admet-2088	1619	9	for	for	ADP
admet-2088	1619	10	apoptosis	apoptosis	NOUN
admet-2088	1619	11	-	-	PUNCT
admet-2088	1619	12	autophagy	autophagy	NOUN
admet-2088	1619	13	-	-	PUNCT
admet-2088	1619	14	ferroptosis	ferroptosis	NOUN
admet-2088	1619	15	induced	induce	VERB
admet-2088	1619	16	combination	combination	NOUN
admet-2088	1619	17	therapy	therapy	NOUN
admet-2088	1619	18	against	against	ADP
admet-2088	1619	19	melanoma	melanoma	NOUN
admet-2088	1619	20	.	.	PUNCT
admet-2088	1620	1	biomaterials	biomaterial	NOUN
admet-2088	1620	2	301	301	NUM
admet-2088	1620	3	(	(	PUNCT
admet-2088	1620	4	2023	2023	NUM
admet-2088	1620	5	)	)	PUNCT
admet-2088	1620	6	122212	122212	NUM
admet-2088	1620	7	.	.	PUNCT
admet-2088	1621	1	https://doi.org/10.1016/j.biomaterials.2023.122212	https://doi.org/10.1016/j.biomaterials.2023.122212	NOUN
admet-2088	1621	2	.	.	PUNCT
admet-2088	1622	1	[	[	X
admet-2088	1622	2	230	230	NUM
admet-2088	1622	3	]	]	PUNCT
admet-2088	1622	4	d.	d.	PROPN
admet-2088	1622	5	ibraheem	ibraheem	PROPN
admet-2088	1622	6	,	,	PUNCT
admet-2088	1622	7	a.	a.	NOUN
admet-2088	1622	8	elaissari	elaissari	PROPN
admet-2088	1622	9	,	,	PUNCT
admet-2088	1622	10	h.	h.	PROPN
admet-2088	1622	11	fessi	fessi	PROPN
admet-2088	1622	12	.	.	PUNCT
admet-2088	1623	1	gene	gene	NOUN
admet-2088	1623	2	therapy	therapy	NOUN
admet-2088	1623	3	and	and	CCONJ
admet-2088	1623	4	dna	dna	NOUN
admet-2088	1623	5	delivery	delivery	NOUN
admet-2088	1623	6	systems	system	NOUN
admet-2088	1623	7	.	.	PUNCT
admet-2088	1624	1	international	international	ADJ
admet-2088	1624	2	journal	journal	PROPN
admet-2088	1624	3	of	of	ADP
admet-2088	1624	4	pharmaceutics	pharmaceutic	NOUN
admet-2088	1624	5	459	459	NUM
admet-2088	1624	6	(	(	PUNCT
admet-2088	1624	7	2014	2014	NUM
admet-2088	1624	8	)	)	PUNCT
admet-2088	1624	9	70	70	NUM
admet-2088	1624	10	-	-	SYM
admet-2088	1624	11	83	83	NUM
admet-2088	1624	12	.	.	PUNCT
admet-2088	1624	13	https://doi.org/10.1016/j.ijpharm.2013.11.041	https://doi.org/10.1016/j.ijpharm.2013.11.041	PROPN
admet-2088	1624	14	.	.	PUNCT
admet-2088	1625	1	[	[	X
admet-2088	1625	2	231	231	NUM
admet-2088	1625	3	]	]	PUNCT
admet-2088	1625	4	m.	m.	NOUN
admet-2088	1625	5	danaeifar	danaeifar	NOUN
admet-2088	1625	6	.	.	PUNCT
admet-2088	1626	1	recent	recent	ADJ
admet-2088	1626	2	advances	advance	NOUN
admet-2088	1626	3	in	in	ADP
admet-2088	1626	4	gene	gene	NOUN
admet-2088	1626	5	therapy	therapy	NOUN
admet-2088	1626	6	:	:	PUNCT
admet-2088	1626	7	genetic	genetic	ADJ
admet-2088	1626	8	bullets	bullet	NOUN
admet-2088	1626	9	to	to	ADP
admet-2088	1626	10	the	the	DET
admet-2088	1626	11	root	root	NOUN
admet-2088	1626	12	of	of	ADP
admet-2088	1626	13	the	the	DET
admet-2088	1626	14	problem	problem	NOUN
admet-2088	1626	15	.	.	PUNCT
admet-2088	1627	1	clinical	clinical	ADJ
admet-2088	1627	2	and	and	CCONJ
admet-2088	1627	3	experimental	experimental	ADJ
admet-2088	1627	4	medicine	medicine	NOUN
admet-2088	1627	5	23	23	NUM
admet-2088	1627	6	(	(	PUNCT
admet-2088	1627	7	2023	2023	NUM
admet-2088	1627	8	)	)	PUNCT
admet-2088	1627	9	1107	1107	NUM
admet-2088	1627	10	-	-	SYM
admet-2088	1627	11	1121	1121	NUM
admet-2088	1627	12	.	.	PUNCT
admet-2088	1628	1	https://doi.org/10.1007/s10238-022-00925-x	https://doi.org/10.1007/s10238-022-00925-x	NOUN
admet-2088	1628	2	.	.	PUNCT
admet-2088	1629	1	[	[	X
admet-2088	1629	2	232	232	X
admet-2088	1629	3	]	]	X
admet-2088	1629	4	y.	y.	PROPN
admet-2088	1629	5	wang	wang	PROPN
admet-2088	1629	6	,	,	PUNCT
admet-2088	1629	7	x.	x.	PROPN
admet-2088	1629	8	ji	ji	PROPN
admet-2088	1629	9	,	,	PUNCT
admet-2088	1629	10	m.	m.	PROPN
admet-2088	1629	11	ruan	ruan	PROPN
admet-2088	1629	12	,	,	PUNCT
admet-2088	1629	13	r.	r.	PROPN
admet-2088	1629	14	song	song	PROPN
admet-2088	1629	15	,	,	PUNCT
admet-2088	1629	16	j.	j.	PROPN
admet-2088	1629	17	dai	dai	PROPN
admet-2088	1629	18	,	,	PUNCT
admet-2088	1629	19	w.	w.	PROPN
admet-2088	1629	20	xue	xue	PROPN
admet-2088	1629	21	.	.	PUNCT
admet-2088	1630	1	worm	worm	NOUN
admet-2088	1630	2	-	-	PUNCT
admet-2088	1630	3	like	like	ADJ
admet-2088	1630	4	biomimetic	biomimetic	ADJ
admet-2088	1630	5	nanoerythrocyte	nanoerythrocyte	NOUN
admet-2088	1630	6	carrying	carry	VERB
admet-2088	1630	7	sirna	sirna	PROPN
admet-2088	1630	8	for	for	ADP
admet-2088	1630	9	melanoma	melanoma	NOUN
admet-2088	1630	10	gene	gene	NOUN
admet-2088	1630	11	therapy	therapy	NOUN
admet-2088	1630	12	.	.	PUNCT
admet-2088	1631	1	small	small	ADJ
admet-2088	1631	2	14	14	NUM
admet-2088	1631	3	(	(	PUNCT
admet-2088	1631	4	2018	2018	NUM
admet-2088	1631	5	)	)	PUNCT
admet-2088	1631	6	1803002	1803002	NUM
admet-2088	1631	7	.	.	PUNCT
admet-2088	1632	1	https://doi.org/10.1002/smll.201803002	https://doi.org/10.1002/smll.201803002	NOUN
admet-2088	1632	2	.	.	PUNCT
admet-2088	1633	1	[	[	X
admet-2088	1633	2	233	233	NUM
admet-2088	1633	3	]	]	X
admet-2088	1633	4	h.j	h.j	PROPN
admet-2088	1633	5	.	.	PROPN
admet-2088	1633	6	han	han	PROPN
admet-2088	1633	7	,	,	PUNCT
admet-2088	1633	8	c.	c.	PROPN
admet-2088	1633	9	ekweremadu	ekweremadu	NOUN
admet-2088	1633	10	,	,	PUNCT
admet-2088	1633	11	n.	n.	PROPN
admet-2088	1633	12	patel	patel	PROPN
admet-2088	1633	13	.	.	PUNCT
admet-2088	1634	1	advanced	advanced	ADJ
admet-2088	1634	2	drug	drug	NOUN
admet-2088	1634	3	delivery	delivery	NOUN
admet-2088	1634	4	system	system	NOUN
admet-2088	1634	5	with	with	ADP
admet-2088	1634	6	nanomaterials	nanomaterial	NOUN
admet-2088	1634	7	for	for	ADP
admet-2088	1634	8	personalised	personalised	ADJ
admet-2088	1634	9	medicine	medicine	NOUN
admet-2088	1634	10	to	to	PART
admet-2088	1634	11	treat	treat	VERB
admet-2088	1634	12	breast	breast	NOUN
admet-2088	1634	13	cancer	cancer	NOUN
admet-2088	1634	14	.	.	PUNCT
admet-2088	1635	1	journal	journal	PROPN
admet-2088	1635	2	of	of	ADP
admet-2088	1635	3	drug	drug	NOUN
admet-2088	1635	4	delivery	delivery	NOUN
admet-2088	1635	5	science	science	NOUN
admet-2088	1635	6	and	and	CCONJ
admet-2088	1635	7	technology	technology	NOUN
admet-2088	1635	8	52	52	NUM
admet-2088	1635	9	(	(	PUNCT
admet-2088	1635	10	2019	2019	NUM
admet-2088	1635	11	)	)	PUNCT
admet-2088	1635	12	1051	1051	NUM
admet-2088	1635	13	-	-	SYM
admet-2088	1635	14	1060	1060	NUM
admet-2088	1635	15	.	.	PUNCT
admet-2088	1636	1	https://doi.org/10.1016/j.jddst.2019.05.024	https://doi.org/10.1016/j.jddst.2019.05.024	NUM
admet-2088	1636	2	.	.	PUNCT
admet-2088	1637	1	[	[	X
admet-2088	1637	2	234	234	NUM
admet-2088	1637	3	]	]	X
admet-2088	1637	4	c.	c.	PROPN
admet-2088	1637	5	fornaguera	fornaguera	PROPN
admet-2088	1637	6	,	,	PUNCT
admet-2088	1637	7	m.	m.	NOUN
admet-2088	1637	8	garcía	garcía	NOUN
admet-2088	1637	9	-	-	PUNCT
admet-2088	1637	10	celma	celma	NOUN
admet-2088	1637	11	.	.	PUNCT
admet-2088	1637	12	personalized	personalized	ADJ
admet-2088	1637	13	nanomedicine	nanomedicine	NOUN
admet-2088	1637	14	:	:	PUNCT
admet-2088	1637	15	a	a	DET
admet-2088	1637	16	revolution	revolution	NOUN
admet-2088	1637	17	at	at	ADP
admet-2088	1637	18	the	the	DET
admet-2088	1637	19	nanoscale	nanoscale	PROPN
admet-2088	1637	20	.	.	PUNCT
admet-2088	1638	1	journal	journal	PROPN
admet-2088	1638	2	of	of	ADP
admet-2088	1638	3	personalized	personalized	ADJ
admet-2088	1638	4	medicine	medicine	NOUN
admet-2088	1638	5	7	7	NUM
admet-2088	1638	6	(	(	PUNCT
admet-2088	1638	7	2017	2017	NUM
admet-2088	1638	8	)	)	PUNCT
admet-2088	1638	9	12	12	NUM
admet-2088	1638	10	.	.	PUNCT
admet-2088	1639	1	https://doi.org/10.3390/jpm7040012	https://doi.org/10.3390/jpm7040012	NOUN
admet-2088	1639	2	.	.	PUNCT
admet-2088	1640	1	©	©	PROPN
admet-2088	1640	2	2023	2023	NUM
admet-2088	1640	3	by	by	ADP
admet-2088	1640	4	the	the	DET
admet-2088	1640	5	authors	author	NOUN
admet-2088	1640	6	;	;	PUNCT
admet-2088	1640	7	licensee	licensee	PROPN
admet-2088	1640	8	iapc	iapc	PROPN
admet-2088	1640	9	,	,	PUNCT
admet-2088	1640	10	zagreb	zagreb	PROPN
admet-2088	1640	11	,	,	PUNCT
admet-2088	1640	12	croatia	croatia	PROPN
admet-2088	1640	13	.	.	PUNCT
admet-2088	1641	1	this	this	DET
admet-2088	1641	2	article	article	NOUN
admet-2088	1641	3	is	be	AUX
admet-2088	1641	4	an	an	DET
admet-2088	1641	5	open	open	ADJ
admet-2088	1641	6	-	-	PUNCT
admet-2088	1641	7	access	access	NOUN
admet-2088	1641	8	article	article	NOUN
admet-2088	1641	9	distributed	distribute	VERB
admet-2088	1641	10	under	under	ADP
admet-2088	1641	11	the	the	DET
admet-2088	1641	12	terms	term	NOUN
admet-2088	1641	13	and	and	CCONJ
admet-2088	1641	14	conditions	condition	NOUN
admet-2088	1641	15	of	of	ADP
admet-2088	1641	16	the	the	DET
admet-2088	1641	17	creative	creative	ADJ
admet-2088	1641	18	commons	common	NOUN
admet-2088	1641	19	attribution	attribution	NOUN
admet-2088	1641	20	license	license	NOUN
admet-2088	1641	21	(	(	PUNCT
admet-2088	1641	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-2088	1641	23	)	)	PUNCT
admet-2088	1641	24	https://doi.org/10.1007/s10103-019-02880-8	https://doi.org/10.1007/s10103-019-02880-8	NUM
admet-2088	1641	25	https://doi.org/10.1038/nri2567	https://doi.org/10.1038/nri2567	ADJ
admet-2088	1641	26	https://doi.org/10.2147/ijn.s238099	https://doi.org/10.2147/ijn.s238099	NOUN
admet-2088	1641	27	https://doi.org/10.1080/10717544.2018.1513609	https://doi.org/10.1080/10717544.2018.1513609	PROPN
admet-2088	1641	28	https://doi.org/10.1038/s41556-018-0250-9	https://doi.org/10.1038/s41556-018-0250-9	NUM
admet-2088	1641	29	https://doi.org/10.1016/j.biopha.2022.113480	https://doi.org/10.1016/j.biopha.2022.113480	NOUN
admet-2088	1641	30	https://doi.org/10.1016/j.jconrel.2015.03.033	https://doi.org/10.1016/j.jconrel.2015.03.033	VERB
admet-2088	1641	31	https://doi.org/10.1016/j.nano.2015.10.012	https://doi.org/10.1016/j.nano.2015.10.012	DET
admet-2088	1641	32	https://doi.org/10.1016/j.biomaterials.2023.122212	https://doi.org/10.1016/j.biomaterials.2023.122212	ADJ
admet-2088	1641	33	https://doi.org/10.1016/j.ijpharm.2013.11.041	https://doi.org/10.1016/j.ijpharm.2013.11.041	ADJ
admet-2088	1641	34	https://doi.org/10.1007/s10238-022-00925-x	https://doi.org/10.1007/s10238-022-00925-x	PROPN
admet-2088	1641	35	https://doi.org/10.1002/smll.201803002	https://doi.org/10.1002/smll.201803002	NOUN
admet-2088	1641	36	https://doi.org/10.1016/j.jddst.2019.05.024	https://doi.org/10.1016/j.jddst.2019.05.024	PROPN
admet-2088	1641	37	https://doi.org/10.3390/jpm7040012	https://doi.org/10.3390/jpm7040012	NOUN
admet-2088	1641	38	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN