id	sid	tid	token	lemma	pos
admet-2338	1	1	investigation	investigation	NOUN
admet-2338	1	2	of	of	ADP
admet-2338	1	3	magnesium	magnesium	NOUN
admet-2338	1	4	aluminometasilicate	aluminometasilicate	NOUN
admet-2338	1	5	(	(	PUNCT
admet-2338	1	6	neusilin	neusilin	PROPN
admet-2338	1	7	us2	us2	PROPN
admet-2338	1	8	)	)	PUNCT
admet-2338	1	9	based	base	VERB
admet-2338	1	10	surface	surface	NOUN
admet-2338	1	11	solid	solid	ADJ
admet-2338	1	12	dispersion	dispersion	NOUN
admet-2338	1	13	of	of	ADP
admet-2338	1	14	sorafenib	sorafenib	NOUN
admet-2338	1	15	tosylate	tosylate	VERB
admet-2338	1	16	using	use	VERB
admet-2338	1	17	qbd	qbd	NOUN
admet-2338	1	18	approach	approach	NOUN
admet-2338	1	19	:	:	PUNCT
admet-2338	1	20	in	in	ADP
admet-2338	1	21	vitro	vitro	X
admet-2338	1	22	and	and	CCONJ
admet-2338	1	23	in	in	ADP
admet-2338	1	24	vivo	vivo	ADJ
admet-2338	1	25	pharmacokinetic	pharmacokinetic	ADJ
admet-2338	1	26	study	study	NOUN
admet-2338	1	27	doi	doi	NOUN
admet-2338	1	28	:	:	PUNCT
admet-2338	1	29	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	ADJ
admet-2338	1	30	687	687	NUM
admet-2338	1	31	admet	admet	X
admet-2338	1	32	&	&	CCONJ
admet-2338	1	33	dmpk	dmpk	PROPN
admet-2338	1	34	12(4	12(4	PROPN
admet-2338	1	35	)	)	PUNCT
admet-2338	1	36	(	(	PUNCT
admet-2338	1	37	2024	2024	NUM
admet-2338	1	38	)	)	PUNCT
admet-2338	1	39	687	687	NUM
admet-2338	1	40	-	-	SYM
admet-2338	1	41	702	702	NUM
admet-2338	1	42	;	;	PUNCT
admet-2338	1	43	doi	doi	NOUN
admet-2338	1	44	:	:	PUNCT
admet-2338	1	45	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	ADJ
admet-2338	1	46	open	open	ADJ
admet-2338	1	47	access	access	NOUN
admet-2338	1	48	:	:	PUNCT
admet-2338	1	49	issn	issn	PROPN
admet-2338	1	50	:	:	PUNCT
admet-2338	1	51	1848	1848	NUM
admet-2338	1	52	-	-	SYM
admet-2338	1	53	7718	7718	NUM
admet-2338	1	54	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-2338	1	55	original	original	ADJ
admet-2338	1	56	scientific	scientific	ADJ
admet-2338	1	57	paper	paper	NOUN
admet-2338	1	58	investigation	investigation	NOUN
admet-2338	1	59	of	of	ADP
admet-2338	1	60	magnesium	magnesium	NOUN
admet-2338	1	61	aluminometasilicate	aluminometasilicate	NOUN
admet-2338	1	62	(	(	PUNCT
admet-2338	1	63	neusilin	neusilin	PROPN
admet-2338	1	64	us2	us2	PROPN
admet-2338	1	65	)	)	PUNCT
admet-2338	1	66	based	base	VERB
admet-2338	1	67	surface	surface	NOUN
admet-2338	1	68	solid	solid	ADJ
admet-2338	1	69	dispersion	dispersion	NOUN
admet-2338	1	70	of	of	ADP
admet-2338	1	71	sorafenib	sorafenib	NOUN
admet-2338	1	72	tosylate	tosylate	VERB
admet-2338	1	73	using	use	VERB
admet-2338	1	74	qbd	qbd	NOUN
admet-2338	1	75	approach	approach	NOUN
admet-2338	1	76	:	:	PUNCT
admet-2338	1	77	in	in	ADP
admet-2338	1	78	vitro	vitro	X
admet-2338	1	79	and	and	CCONJ
admet-2338	1	80	in	in	ADP
admet-2338	1	81	vivo	vivo	ADJ
admet-2338	1	82	pharmacokinetic	pharmacokinetic	ADJ
admet-2338	1	83	study	study	NOUN
admet-2338	1	84	bijoy	bijoy	PROPN
admet-2338	1	85	kumar	kumar	PROPN
admet-2338	1	86	panda1	panda1	PROPN
admet-2338	1	87	,	,	PUNCT
admet-2338	1	88	bothiraja	bothiraja	PROPN
admet-2338	1	89	chellampillai2	chellampillai2	PROPN
admet-2338	1	90	,	,	PUNCT
admet-2338	1	91	sharad	sharad	PROPN
admet-2338	1	92	ghodake3	ghodake3	PROPN
admet-2338	1	93	,	,	PUNCT
admet-2338	1	94	ashwin	ashwin	PROPN
admet-2338	1	95	j.	j.	PROPN
admet-2338	1	96	mali3	mali3	PROPN
admet-2338	1	97	and	and	CCONJ
admet-2338	1	98	ravindra	ravindra	PROPN
admet-2338	1	99	kamble3	kamble3	PROPN
admet-2338	1	100	,	,	PUNCT
admet-2338	1	101	*	*	PROPN
admet-2338	1	102	1department	1department	NUM
admet-2338	1	103	of	of	ADP
admet-2338	1	104	pharmacy	pharmacy	NOUN
admet-2338	1	105	practice	practice	NOUN
admet-2338	1	106	,	,	PUNCT
admet-2338	1	107	krishna	krishna	PROPN
admet-2338	1	108	institute	institute	PROPN
admet-2338	1	109	of	of	ADP
admet-2338	1	110	pharmacy	pharmacy	NOUN
admet-2338	1	111	,	,	PUNCT
admet-2338	1	112	krishna	krishna	PROPN
admet-2338	1	113	vishwa	vishwa	PROPN
admet-2338	1	114	vidyapeeth	vidyapeeth	PROPN
admet-2338	1	115	(	(	PUNCT
admet-2338	1	116	deemed	deem	VERB
admet-2338	1	117	to	to	PART
admet-2338	1	118	be	be	AUX
admet-2338	1	119	university	university	NOUN
admet-2338	1	120	)	)	PUNCT
admet-2338	1	121	,	,	PUNCT
admet-2338	1	122	karad	karad	PROPN
admet-2338	1	123	,	,	PUNCT
admet-2338	1	124	maharashtra	maharashtra	PROPN
admet-2338	1	125	,	,	PUNCT
admet-2338	1	126	india	india	PROPN
admet-2338	1	127	2department	2department	PROPN
admet-2338	1	128	of	of	ADP
admet-2338	1	129	pharmaceutics	pharmaceutic	NOUN
admet-2338	1	130	,	,	PUNCT
admet-2338	1	131	goa	goa	PROPN
admet-2338	1	132	college	college	PROPN
admet-2338	1	133	of	of	ADP
admet-2338	1	134	pharmacy	pharmacy	NOUN
admet-2338	1	135	,	,	PUNCT
admet-2338	1	136	goa	goa	PROPN
admet-2338	1	137	university	university	PROPN
admet-2338	1	138	,	,	PUNCT
admet-2338	1	139	panaji	panaji	PROPN
admet-2338	1	140	,	,	PUNCT
admet-2338	1	141	goa	goa	PROPN
admet-2338	1	142	,	,	PUNCT
admet-2338	1	143	india	india	PROPN
admet-2338	1	144	3department	3department	PROPN
admet-2338	1	145	of	of	ADP
admet-2338	1	146	pharmaceutics	pharmaceutic	NOUN
admet-2338	1	147	,	,	PUNCT
admet-2338	1	148	poona	poona	PROPN
admet-2338	1	149	college	college	PROPN
admet-2338	1	150	of	of	ADP
admet-2338	1	151	pharmacy	pharmacy	NOUN
admet-2338	1	152	,	,	PUNCT
admet-2338	1	153	bharati	bharati	PROPN
admet-2338	1	154	vidyapeeth	vidyapeeth	PROPN
admet-2338	1	155	(	(	PUNCT
admet-2338	1	156	deemed	deem	VERB
admet-2338	1	157	to	to	PART
admet-2338	1	158	be	be	AUX
admet-2338	1	159	university	university	NOUN
admet-2338	1	160	)	)	PUNCT
admet-2338	1	161	,	,	PUNCT
admet-2338	1	162	pune	pune	NOUN
admet-2338	1	163	,	,	PUNCT
admet-2338	1	164	maharashtra	maharashtra	PROPN
admet-2338	1	165	,	,	PUNCT
admet-2338	1	166	india	india	PROPN
admet-2338	1	167	*	*	PUNCT
admet-2338	1	168	corresponding	correspond	VERB
admet-2338	1	169	author	author	NOUN
admet-2338	1	170	:	:	PUNCT
admet-2338	1	171	e	e	NOUN
admet-2338	1	172	-	-	NOUN
admet-2338	1	173	mail	mail	NOUN
admet-2338	1	174	:	:	PUNCT
admet-2338	2	1	kravi_73@rediffmail.com	kravi_73@rediffmail.com	X
admet-2338	2	2	;	;	PUNCT
admet-2338	2	3	tel	tel	PROPN
admet-2338	2	4	.	.	PUNCT
admet-2338	2	5	:	:	PUNCT
admet-2338	2	6	+91	+91	PROPN
admet-2338	2	7	-	-	SYM
admet-2338	2	8	9881049010	9881049010	NUM
admet-2338	2	9	received	receive	VERB
admet-2338	2	10	:	:	PUNCT
admet-2338	2	11	march	march	PROPN
admet-2338	2	12	29	29	NUM
admet-2338	2	13	,	,	PUNCT
admet-2338	2	14	2024	2024	NUM
admet-2338	2	15	;	;	PUNCT
admet-2338	2	16	revised	revise	VERB
admet-2338	2	17	:	:	PUNCT
admet-2338	2	18	july	july	PROPN
admet-2338	2	19	23	23	NUM
admet-2338	2	20	,	,	PUNCT
admet-2338	2	21	2024	2024	NUM
admet-2338	2	22	;	;	PUNCT
admet-2338	2	23	published	publish	VERB
admet-2338	2	24	:	:	PUNCT
admet-2338	2	25	august	august	PROPN
admet-2338	2	26	9,2024	9,2024	NUM
admet-2338	2	27	abstract	abstract	ADJ
admet-2338	2	28	background	background	NOUN
admet-2338	2	29	and	and	CCONJ
admet-2338	2	30	purpose	purpose	NOUN
admet-2338	2	31	:	:	PUNCT
admet-2338	2	32	sorafenib	sorafenib	PROPN
admet-2338	2	33	tosylate	tosylate	VERB
admet-2338	2	34	(	(	PUNCT
admet-2338	2	35	sfn	sfn	PROPN
admet-2338	2	36	)	)	PUNCT
admet-2338	2	37	,	,	PUNCT
admet-2338	2	38	a	a	DET
admet-2338	2	39	potent	potent	ADJ
admet-2338	2	40	multikinase	multikinase	NOUN
admet-2338	2	41	inhibitor	inhibitor	NOUN
admet-2338	2	42	,	,	PUNCT
admet-2338	2	43	is	be	AUX
admet-2338	2	44	used	use	VERB
admet-2338	2	45	for	for	ADP
admet-2338	2	46	the	the	DET
admet-2338	2	47	treatment	treatment	NOUN
admet-2338	2	48	of	of	ADP
admet-2338	2	49	various	various	ADJ
admet-2338	2	50	cancers	cancer	NOUN
admet-2338	2	51	.	.	PUNCT
admet-2338	3	1	however	however	ADV
admet-2338	3	2	,	,	PUNCT
admet-2338	3	3	it	it	PRON
admet-2338	3	4	shows	show	VERB
admet-2338	3	5	limited	limited	ADJ
admet-2338	3	6	therapeutic	therapeutic	ADJ
admet-2338	3	7	applications	application	NOUN
admet-2338	3	8	due	due	ADP
admet-2338	3	9	to	to	ADP
admet-2338	3	10	its	its	PRON
admet-2338	3	11	poor	poor	ADJ
admet-2338	3	12	biopharmaceutical	biopharmaceutical	ADJ
admet-2338	3	13	properties	property	NOUN
admet-2338	3	14	.	.	PUNCT
admet-2338	4	1	the	the	DET
admet-2338	4	2	aim	aim	NOUN
admet-2338	4	3	of	of	ADP
admet-2338	4	4	the	the	DET
admet-2338	4	5	present	present	ADJ
admet-2338	4	6	investigation	investigation	NOUN
admet-2338	4	7	is	be	AUX
admet-2338	4	8	to	to	PART
admet-2338	4	9	develop	develop	VERB
admet-2338	4	10	surface	surface	NOUN
admet-2338	4	11	solid	solid	ADJ
admet-2338	4	12	dispersion	dispersion	NOUN
admet-2338	4	13	(	(	PUNCT
admet-2338	4	14	ssd	ssd	NOUN
admet-2338	4	15	)	)	PUNCT
admet-2338	4	16	of	of	ADP
admet-2338	4	17	sfn	sfn	PROPN
admet-2338	4	18	using	use	VERB
admet-2338	4	19	adsorbent	adsorbent	NOUN
admet-2338	4	20	to	to	PART
admet-2338	4	21	improve	improve	VERB
admet-2338	4	22	its	its	PRON
admet-2338	4	23	solubility	solubility	NOUN
admet-2338	4	24	,	,	PUNCT
admet-2338	4	25	bioavailability	bioavailability	NOUN
admet-2338	4	26	and	and	CCONJ
admet-2338	4	27	therapeutic	therapeutic	ADJ
admet-2338	4	28	efficacy	efficacy	NOUN
admet-2338	4	29	.	.	PUNCT
admet-2338	5	1	experimental	experimental	ADJ
admet-2338	5	2	approach	approach	NOUN
admet-2338	5	3	:	:	PUNCT
admet-2338	5	4	the	the	DET
admet-2338	5	5	sfnssd	sfnssd	NOUN
admet-2338	5	6	was	be	AUX
admet-2338	5	7	prepared	prepare	VERB
admet-2338	5	8	by	by	ADP
admet-2338	5	9	modified	modify	VERB
admet-2338	5	10	solvent	solvent	ADJ
admet-2338	5	11	evaporation	evaporation	NOUN
admet-2338	5	12	technique	technique	NOUN
admet-2338	5	13	using	use	VERB
admet-2338	5	14	neusilin	neusilin	PROPN
admet-2338	5	15	us2	us2	PROPN
admet-2338	5	16	(	(	PUNCT
admet-2338	5	17	magnesium	magnesium	NOUN
admet-2338	5	18	aluminometasilicate	aluminometasilicate	NOUN
admet-2338	5	19	)	)	PUNCT
admet-2338	5	20	as	as	ADP
admet-2338	5	21	an	an	DET
admet-2338	5	22	adsorbent	adsorbent	NOUN
admet-2338	5	23	and	and	CCONJ
admet-2338	5	24	sodium	sodium	NOUN
admet-2338	5	25	dodecyl	dodecyl	NOUN
admet-2338	5	26	sulphate	sulphate	NOUN
admet-2338	5	27	as	as	ADP
admet-2338	5	28	a	a	DET
admet-2338	5	29	surfactant	surfactant	NOUN
admet-2338	5	30	.	.	PUNCT
admet-2338	6	1	sfn	sfn	PROPN
admet-2338	6	2	-	-	PUNCT
admet-2338	6	3	ssd	ssd	NOUN
admet-2338	6	4	was	be	AUX
admet-2338	6	5	optimized	optimize	VERB
admet-2338	6	6	by	by	ADP
admet-2338	6	7	adopting	adopt	VERB
admet-2338	6	8	the	the	DET
admet-2338	6	9	design	design	NOUN
admet-2338	6	10	of	of	ADP
admet-2338	6	11	experiment	experiment	NOUN
admet-2338	6	12	(	(	PUNCT
admet-2338	6	13	doe	doe	NOUN
admet-2338	6	14	)	)	PUNCT
admet-2338	6	15	using	use	VERB
admet-2338	6	16	32	32	NUM
admet-2338	6	17	factorial	factorial	ADJ
admet-2338	6	18	designs	design	NOUN
admet-2338	6	19	and	and	CCONJ
admet-2338	6	20	characterized	characterize	VERB
admet-2338	6	21	in	in	ADP
admet-2338	6	22	terms	term	NOUN
admet-2338	6	23	of	of	ADP
admet-2338	6	24	in	in	ADP
admet-2338	6	25	-	-	PUNCT
admet-2338	6	26	vitro	vitro	X
admet-2338	6	27	and	and	CCONJ
admet-2338	6	28	in	in	ADP
admet-2338	6	29	-	-	PUNCT
admet-2338	6	30	vivo	vivo	NOUN
admet-2338	6	31	efficacy	efficacy	NOUN
admet-2338	6	32	.	.	PUNCT
admet-2338	7	1	key	key	ADJ
admet-2338	7	2	results	result	NOUN
admet-2338	7	3	:	:	PUNCT
admet-2338	7	4	the	the	DET
admet-2338	7	5	obtained	obtain	VERB
admet-2338	7	6	sfn	sfn	PROPN
admet-2338	7	7	-	-	PUNCT
admet-2338	7	8	ssd	ssd	NOUN
admet-2338	7	9	showed	show	VERB
admet-2338	7	10	more	more	ADJ
admet-2338	7	11	than	than	ADP
admet-2338	7	12	20	20	NUM
admet-2338	7	13	-	-	ADJ
admet-2338	7	14	fold	fold	ADJ
admet-2338	7	15	improvement	improvement	NOUN
admet-2338	7	16	in	in	ADP
admet-2338	7	17	sfn	sfn	PROPN
admet-2338	7	18	solubility	solubility	NOUN
admet-2338	7	19	.	.	PUNCT
admet-2338	8	1	the	the	DET
admet-2338	8	2	ftir	ftir	PROPN
admet-2338	8	3	depicted	depict	VERB
admet-2338	8	4	hydrogen	hydrogen	NOUN
admet-2338	8	5	bonding	bonding	NOUN
admet-2338	8	6	between	between	ADP
admet-2338	8	7	sfn	sfn	PROPN
admet-2338	8	8	and	and	CCONJ
admet-2338	8	9	neusilin	neusilin	NOUN
admet-2338	8	10	.	.	PUNCT
admet-2338	9	1	further	far	ADV
admet-2338	9	2	,	,	PUNCT
admet-2338	9	3	pxrd	pxrd	PROPN
admet-2338	9	4	and	and	CCONJ
admet-2338	9	5	dsc	dsc	NOUN
admet-2338	9	6	indicated	indicate	VERB
admet-2338	9	7	the	the	DET
admet-2338	9	8	molecular	molecular	ADJ
admet-2338	9	9	dispersion	dispersion	NOUN
admet-2338	9	10	of	of	ADP
admet-2338	9	11	sfn	sfn	PROPN
admet-2338	9	12	to	to	PART
admet-2338	9	13	be	be	AUX
admet-2338	9	14	amorphous	amorphous	ADJ
admet-2338	9	15	.	.	PUNCT
admet-2338	10	1	sfn	sfn	PROPN
admet-2338	10	2	-	-	PUNCT
admet-2338	10	3	ssd	ssd	PROPN
admet-2338	10	4	and	and	CCONJ
admet-2338	10	5	sfn	sfn	ADJ
admet-2338	10	6	immediate	immediate	ADJ
admet-2338	10	7	release	release	NOUN
admet-2338	10	8	tablets	tablet	NOUN
admet-2338	10	9	reflected	reflect	VERB
admet-2338	10	10	cumulative	cumulative	ADJ
admet-2338	10	11	release	release	NOUN
admet-2338	10	12	of	of	ADP
admet-2338	10	13	97.13	97.13	NUM
admet-2338	10	14	and	and	CCONJ
admet-2338	10	15	29.93	29.93	NUM
admet-2338	10	16	%	%	NOUN
admet-2338	10	17	in	in	ADP
admet-2338	10	18	1	1	NUM
admet-2338	10	19	h.	h.	NOUN
admet-2338	10	20	the	the	DET
admet-2338	10	21	pharmacokinetics	pharmacokinetic	NOUN
admet-2338	10	22	study	study	NOUN
admet-2338	10	23	of	of	ADP
admet-2338	10	24	sfn	sfn	PROPN
admet-2338	10	25	-	-	PUNCT
admet-2338	10	26	ssd	ssd	NOUN
admet-2338	10	27	showed	show	VERB
admet-2338	10	28	2	2	NUM
admet-2338	10	29	and	and	CCONJ
admet-2338	10	30	6.5	6.5	NUM
admet-2338	10	31	-	-	ADJ
admet-2338	10	32	fold	fold	ADJ
admet-2338	10	33	improvement	improvement	NOUN
admet-2338	10	34	in	in	ADP
admet-2338	10	35	maximum	maximum	ADJ
admet-2338	10	36	concentration	concentration	NOUN
admet-2338	10	37	(	(	PUNCT
admet-2338	10	38	cmax	cmax	NOUN
admet-2338	10	39	,	,	PUNCT
admet-2338	10	40	)	)	PUNCT
admet-2338	10	41	and	and	CCONJ
admet-2338	10	42	area	area	NOUN
admet-2338	10	43	under	under	ADP
admet-2338	10	44	the	the	DET
admet-2338	10	45	curve	curve	NOUN
admet-2338	10	46	(	(	PUNCT
admet-2338	10	47	auc0	auc0	PROPN
admet-2338	10	48	-	-	PUNCT
admet-2338	10	49	t	t	PROPN
admet-2338	10	50	)	)	PUNCT
admet-2338	10	51	as	as	SCONJ
admet-2338	10	52	compared	compare	VERB
admet-2338	10	53	to	to	ADP
admet-2338	10	54	pure	pure	ADJ
admet-2338	10	55	sfn	sfn	PROPN
admet-2338	10	56	due	due	ADP
admet-2338	10	57	to	to	ADP
admet-2338	10	58	faster	fast	ADJ
admet-2338	10	59	drug	drug	NOUN
admet-2338	10	60	release	release	NOUN
admet-2338	10	61	at	at	ADP
admet-2338	10	62	the	the	DET
admet-2338	10	63	absorption	absorption	NOUN
admet-2338	10	64	site	site	NOUN
admet-2338	10	65	.	.	PUNCT
admet-2338	11	1	conclusion	conclusion	NOUN
admet-2338	11	2	:	:	PUNCT
admet-2338	11	3	the	the	DET
admet-2338	11	4	study	study	NOUN
admet-2338	11	5	concluded	conclude	VERB
admet-2338	11	6	that	that	SCONJ
admet-2338	11	7	the	the	DET
admet-2338	11	8	ssd	ssd	NOUN
admet-2338	11	9	could	could	AUX
admet-2338	11	10	be	be	AUX
admet-2338	11	11	a	a	DET
admet-2338	11	12	scalable	scalable	ADJ
admet-2338	11	13	formulation	formulation	NOUN
admet-2338	11	14	approach	approach	NOUN
admet-2338	11	15	and	and	CCONJ
admet-2338	11	16	more	more	ADJ
admet-2338	11	17	industry	industry	NOUN
admet-2338	11	18	-	-	PUNCT
admet-2338	11	19	friendly	friendly	ADJ
admet-2338	11	20	technology	technology	NOUN
admet-2338	11	21	to	to	PART
admet-2338	11	22	improve	improve	VERB
admet-2338	11	23	the	the	DET
admet-2338	11	24	biopharmaceutical	biopharmaceutical	ADJ
admet-2338	11	25	properties	property	NOUN
admet-2338	11	26	of	of	ADP
admet-2338	11	27	sfn	sfn	PROPN
admet-2338	11	28	.	.	PUNCT
admet-2338	12	1	©	©	PROPN
admet-2338	12	2	2024	2024	NUM
admet-2338	12	3	by	by	ADP
admet-2338	12	4	the	the	DET
admet-2338	12	5	authors	author	NOUN
admet-2338	12	6	.	.	PUNCT
admet-2338	13	1	this	this	DET
admet-2338	13	2	article	article	NOUN
admet-2338	13	3	is	be	AUX
admet-2338	13	4	an	an	DET
admet-2338	13	5	open	open	ADJ
admet-2338	13	6	-	-	PUNCT
admet-2338	13	7	access	access	NOUN
admet-2338	13	8	article	article	NOUN
admet-2338	13	9	distributed	distribute	VERB
admet-2338	13	10	under	under	ADP
admet-2338	13	11	the	the	DET
admet-2338	13	12	terms	term	NOUN
admet-2338	13	13	and	and	CCONJ
admet-2338	13	14	conditions	condition	NOUN
admet-2338	13	15	of	of	ADP
admet-2338	13	16	the	the	DET
admet-2338	13	17	creative	creative	ADJ
admet-2338	13	18	commons	common	NOUN
admet-2338	13	19	attribution	attribution	NOUN
admet-2338	13	20	license	license	NOUN
admet-2338	13	21	(	(	PUNCT
admet-2338	13	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2338	13	23	)	)	PUNCT
admet-2338	13	24	.	.	PUNCT
admet-2338	14	1	keywords	keyword	NOUN
admet-2338	14	2	neusilin	neusilin	PROPN
admet-2338	14	3	®	®	PROPN
admet-2338	14	4	us2	us2	PROPN
admet-2338	14	5	,	,	PUNCT
admet-2338	14	6	quality	quality	NOUN
admet-2338	14	7	by	by	ADP
admet-2338	14	8	design	design	NOUN
admet-2338	14	9	,	,	PUNCT
admet-2338	14	10	sorafenib	sorafenib	NOUN
admet-2338	14	11	,	,	PUNCT
admet-2338	14	12	pharmacokinetic	pharmacokinetic	ADJ
admet-2338	14	13	analysis	analysis	NOUN
admet-2338	14	14	introduction	introduction	NOUN
admet-2338	14	15	sorafenib	sorafenib	NOUN
admet-2338	14	16	tosylate	tosylate	VERB
admet-2338	14	17	(	(	PUNCT
admet-2338	14	18	sfn	sfn	PROPN
admet-2338	14	19	)	)	PUNCT
admet-2338	14	20	,	,	PUNCT
admet-2338	14	21	a	a	DET
admet-2338	14	22	potent	potent	ADJ
admet-2338	14	23	multikinase	multikinase	NOUN
admet-2338	14	24	inhibitor	inhibitor	NOUN
admet-2338	14	25	,	,	PUNCT
admet-2338	14	26	is	be	AUX
admet-2338	14	27	used	use	VERB
admet-2338	14	28	for	for	ADP
admet-2338	14	29	the	the	DET
admet-2338	14	30	treatment	treatment	NOUN
admet-2338	14	31	of	of	ADP
admet-2338	14	32	thyroid	thyroid	NOUN
admet-2338	14	33	carcinoma	carcinoma	NOUN
admet-2338	14	34	,	,	PUNCT
admet-2338	14	35	advanced	advanced	ADJ
admet-2338	14	36	renal	renal	ADJ
admet-2338	14	37	cell	cell	NOUN
admet-2338	14	38	carcinoma	carcinoma	NOUN
admet-2338	14	39	and	and	CCONJ
admet-2338	14	40	unresectable	unresectable	ADJ
admet-2338	14	41	hepatocellular	hepatocellular	ADJ
admet-2338	14	42	carcinoma	carcinoma	NOUN
admet-2338	15	1	[	[	X
admet-2338	15	2	1	1	NUM
admet-2338	15	3	]	]	PUNCT
admet-2338	15	4	.	.	PUNCT
admet-2338	16	1	sfn	sfn	PROPN
admet-2338	16	2	is	be	AUX
admet-2338	16	3	a	a	DET
admet-2338	16	4	bi	bi	ADJ
admet-2338	16	5	-	-	ADJ
admet-2338	16	6	aryl	aryl	ADJ
admet-2338	16	7	urea	urea	NOUN
admet-2338	16	8	and	and	CCONJ
admet-2338	16	9	an	an	DET
admet-2338	16	10	oral	oral	ADJ
admet-2338	16	11	multikinase	multikinase	NOUN
admet-2338	16	12	inhibitor	inhibitor	NOUN
admet-2338	16	13	.	.	PUNCT
admet-2338	17	1	it	it	PRON
admet-2338	17	2	consists	consist	VERB
admet-2338	17	3	of	of	ADP
admet-2338	17	4	derivatives	derivative	NOUN
admet-2338	17	5	of	of	ADP
admet-2338	17	6	bioaryl	bioaryl	PROPN
admet-2338	17	7	urea	urea	PROPN
admet-2338	17	8	joined	join	VERB
admet-2338	17	9	to	to	ADP
admet-2338	17	10	a	a	DET
admet-2338	17	11	pyridine-2	pyridine-2	NUM
admet-2338	17	12	-	-	PUNCT
admet-2338	17	13	carboxamide	carboxamide	NOUN
admet-2338	17	14	group	group	NOUN
admet-2338	17	15	,	,	PUNCT
admet-2338	17	16	as	as	SCONJ
admet-2338	17	17	shown	show	VERB
admet-2338	17	18	in	in	ADP
admet-2338	17	19	figure	figure	NOUN
admet-2338	17	20	1	1	NUM
admet-2338	17	21	.	.	PUNCT
admet-2338	18	1	sfn	sfn	NOUN
admet-2338	18	2	acts	act	VERB
admet-2338	18	3	by	by	ADP
admet-2338	18	4	blocking	block	VERB
admet-2338	18	5	the	the	DET
admet-2338	18	6	platelet	platelet	NOUN
admet-2338	18	7	-	-	PUNCT
admet-2338	18	8	derived	derive	VERB
admet-2338	18	9	growth	growth	NOUN
admet-2338	18	10	factor	factor	NOUN
admet-2338	18	11	receptor	receptor	NOUN
admet-2338	18	12	(	(	PUNCT
admet-2338	18	13	pdgfr	pdgfr	ADJ
admet-2338	18	14	)	)	PUNCT
admet-2338	18	15	,	,	PUNCT
admet-2338	18	16	c	c	X
admet-2338	18	17	-	-	PUNCT
admet-2338	18	18	kit	kit	NOUN
admet-2338	18	19	,	,	PUNCT
admet-2338	18	20	flt-3	flt-3	NOUN
admet-2338	18	21	,	,	PUNCT
admet-2338	18	22	and	and	CCONJ
admet-2338	18	23	the	the	DET
admet-2338	18	24	vascular	vascular	ADJ
admet-2338	18	25	endothelial	endothelial	ADJ
admet-2338	18	26	growth	growth	NOUN
admet-2338	18	27	factor	factor	NOUN
admet-2338	18	28	receptor	receptor	NOUN
admet-2338	18	29	(	(	PUNCT
admet-2338	18	30	vegfr)-3	vegfr)-3	PROPN
admet-2338	18	31	responsible	responsible	ADJ
admet-2338	18	32	for	for	ADP
admet-2338	18	33	cancer	cancer	NOUN
admet-2338	18	34	cell	cell	NOUN
admet-2338	18	35	growth	growth	NOUN
admet-2338	18	36	and	and	CCONJ
admet-2338	18	37	angiogenesis	angiogenesis	NOUN
admet-2338	18	38	.	.	PUNCT
admet-2338	19	1	sfn	sfn	PROPN
admet-2338	19	2	is	be	AUX
admet-2338	19	3	available	available	ADJ
admet-2338	19	4	as	as	ADP
admet-2338	19	5	film	film	NOUN
admet-2338	19	6	-	-	PUNCT
admet-2338	19	7	coated	coat	VERB
admet-2338	19	8	tablets	tablet	NOUN
admet-2338	19	9	under	under	ADP
admet-2338	19	10	the	the	DET
admet-2338	19	11	brand	brand	NOUN
admet-2338	19	12	name	name	PROPN
admet-2338	19	13	nexavar	nexavar	PROPN
admet-2338	19	14	®	®	NOUN
admet-2338	19	15	(	(	PUNCT
admet-2338	19	16	bayer	bayer	PROPN
admet-2338	19	17	healthcare	healthcare	PROPN
admet-2338	19	18	pharmaceuticals	pharmaceuticals	PROPN
admet-2338	19	19	inc	inc	PROPN
admet-2338	19	20	.	.	PROPN
admet-2338	19	21	)	)	PUNCT
admet-2338	19	22	.	.	PUNCT
admet-2338	20	1	however	however	ADV
admet-2338	20	2	,	,	PUNCT
admet-2338	20	3	it	it	PRON
admet-2338	20	4	shows	show	VERB
admet-2338	20	5	limited	limited	ADJ
admet-2338	20	6	therapeutic	therapeutic	ADJ
admet-2338	20	7	applications	application	NOUN
admet-2338	20	8	due	due	ADP
admet-2338	20	9	to	to	ADP
admet-2338	20	10	its	its	PRON
admet-2338	20	11	poor	poor	ADJ
admet-2338	20	12	biopharmaceutical	biopharmaceutical	ADJ
admet-2338	20	13	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	VERB
admet-2338	20	14	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	PROPN
admet-2338	20	15	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-2338	20	16	mailto:kravi_73@rediffmail.com	mailto:kravi_73@rediffmail.com	PROPN
admet-2338	21	1	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2338	21	2	b.	b.	PROPN
admet-2338	21	3	kumar	kumar	PROPN
admet-2338	21	4	panda	panda	PROPN
admet-2338	21	5	et	et	PROPN
admet-2338	21	6	al	al	PROPN
admet-2338	21	7	.	.	PROPN
admet-2338	21	8	admet	admet	PROPN
admet-2338	21	9	&	&	CCONJ
admet-2338	21	10	dmpk	dmpk	PROPN
admet-2338	21	11	12(4	12(4	PROPN
admet-2338	21	12	)	)	PUNCT
admet-2338	21	13	(	(	PUNCT
admet-2338	21	14	2024	2024	NUM
admet-2338	21	15	)	)	PUNCT
admet-2338	21	16	687	687	NUM
admet-2338	21	17	-	-	SYM
admet-2338	21	18	702	702	NUM
admet-2338	21	19	688	688	NUM
admet-2338	21	20	properties	property	NOUN
admet-2338	21	21	,	,	PUNCT
admet-2338	21	22	such	such	ADJ
admet-2338	21	23	as	as	ADP
admet-2338	21	24	higher	high	ADJ
admet-2338	21	25	lipophilicity	lipophilicity	NOUN
admet-2338	21	26	(	(	PUNCT
admet-2338	21	27	log	log	VERB
admet-2338	21	28	p	p	NOUN
admet-2338	21	29	=	=	NOUN
admet-2338	21	30	4	4	NUM
admet-2338	21	31	)	)	PUNCT
admet-2338	21	32	,	,	PUNCT
admet-2338	21	33	bcs	bcs	NOUN
admet-2338	21	34	class	class	PROPN
admet-2338	21	35	ii	ii	PROPN
admet-2338	21	36	(	(	PUNCT
admet-2338	21	37	low	low	ADJ
admet-2338	21	38	solubility	solubility	NOUN
admet-2338	21	39	and	and	CCONJ
admet-2338	21	40	higher	high	ADJ
admet-2338	21	41	permeability	permeability	NOUN
admet-2338	21	42	)	)	PUNCT
admet-2338	21	43	,	,	PUNCT
admet-2338	21	44	solubility	solubility	NOUN
admet-2338	21	45	-	-	PUNCT
admet-2338	21	46	limited	limit	VERB
admet-2338	21	47	absorption	absorption	NOUN
admet-2338	21	48	,	,	PUNCT
admet-2338	21	49	and	and	CCONJ
admet-2338	21	50	relative	relative	ADJ
admet-2338	21	51	bioavailability	bioavailability	NOUN
admet-2338	21	52	of	of	ADP
admet-2338	21	53	38	38	NUM
admet-2338	21	54	to	to	PART
admet-2338	21	55	49	49	NUM
admet-2338	21	56	%	%	NOUN
admet-2338	21	57	with	with	ADP
admet-2338	21	58	the	the	DET
admet-2338	21	59	side	side	NOUN
admet-2338	21	60	effects	effect	NOUN
admet-2338	21	61	of	of	ADP
admet-2338	21	62	hand	hand	NOUN
admet-2338	21	63	-	-	PUNCT
admet-2338	21	64	foot	foot	NOUN
admet-2338	21	65	skin	skin	NOUN
admet-2338	21	66	responses	response	NOUN
admet-2338	21	67	,	,	PUNCT
admet-2338	21	68	diarrhea	diarrhea	NOUN
admet-2338	21	69	,	,	PUNCT
admet-2338	21	70	and	and	CCONJ
admet-2338	21	71	weariness	weariness	NOUN
admet-2338	21	72	[	[	X
admet-2338	21	73	2	2	NUM
admet-2338	21	74	-	-	SYM
admet-2338	21	75	4	4	NUM
admet-2338	21	76	]	]	PUNCT
admet-2338	21	77	.	.	PUNCT
admet-2338	22	1	various	various	ADJ
admet-2338	22	2	formulations	formulation	NOUN
admet-2338	22	3	such	such	ADJ
admet-2338	22	4	as	as	ADP
admet-2338	22	5	lipid	lipid	NOUN
admet-2338	22	6	-	-	PUNCT
admet-2338	22	7	coated	coat	VERB
admet-2338	22	8	nanodiamond	nanodiamond	NOUN
admet-2338	22	9	,	,	PUNCT
admet-2338	22	10	solid	solid	ADJ
admet-2338	22	11	lipid	lipid	NOUN
admet-2338	22	12	nanoparticle	nanoparticle	NOUN
admet-2338	22	13	,	,	PUNCT
admet-2338	22	14	lipidand	lipidand	NOUN
admet-2338	22	15	poly	poly	NOUN
admet-2338	22	16	(	(	PUNCT
admet-2338	22	17	ethylene	ethylene	NOUN
admet-2338	22	18	glycol)-coated	glycol)-coate	VERB
admet-2338	22	19	nanoparticle	nanoparticle	NOUN
admet-2338	22	20	,	,	PUNCT
admet-2338	22	21	suspension	suspension	NOUN
admet-2338	22	22	,	,	PUNCT
admet-2338	22	23	nanomatrix	nanomatrix	NOUN
admet-2338	22	24	,	,	PUNCT
admet-2338	22	25	and	and	CCONJ
admet-2338	22	26	cyclodextrin	cyclodextrin	NOUN
admet-2338	22	27	-	-	PUNCT
admet-2338	22	28	based	base	VERB
admet-2338	22	29	complexes	complex	NOUN
admet-2338	22	30	have	have	AUX
admet-2338	22	31	been	be	AUX
admet-2338	22	32	developed	develop	VERB
admet-2338	22	33	to	to	PART
admet-2338	22	34	improve	improve	VERB
admet-2338	22	35	its	its	PRON
admet-2338	22	36	solubility	solubility	NOUN
admet-2338	22	37	,	,	PUNCT
admet-2338	22	38	bioavailability	bioavailability	NOUN
admet-2338	22	39	,	,	PUNCT
admet-2338	22	40	and	and	CCONJ
admet-2338	22	41	therapeutic	therapeutic	ADJ
admet-2338	22	42	efficacy	efficacy	NOUN
admet-2338	22	43	of	of	ADP
admet-2338	22	44	sfn	sfn	PROPN
admet-2338	23	1	[	[	X
admet-2338	23	2	5	5	NUM
admet-2338	23	3	]	]	PUNCT
admet-2338	23	4	.	.	PUNCT
admet-2338	24	1	however	however	ADV
admet-2338	24	2	,	,	PUNCT
admet-2338	24	3	each	each	DET
admet-2338	24	4	formulation	formulation	NOUN
admet-2338	24	5	has	have	VERB
admet-2338	24	6	its	its	PRON
admet-2338	24	7	limitations	limitation	NOUN
admet-2338	24	8	.	.	PUNCT
admet-2338	25	1	there	there	PRON
admet-2338	25	2	is	be	VERB
admet-2338	25	3	a	a	DET
admet-2338	25	4	need	need	NOUN
admet-2338	25	5	for	for	ADP
admet-2338	25	6	a	a	DET
admet-2338	25	7	simple	simple	ADJ
admet-2338	25	8	,	,	PUNCT
admet-2338	25	9	conventional	conventional	ADJ
admet-2338	25	10	and	and	CCONJ
admet-2338	25	11	novel	novel	ADJ
admet-2338	25	12	formulation	formulation	NOUN
admet-2338	25	13	that	that	PRON
admet-2338	25	14	could	could	AUX
admet-2338	25	15	improve	improve	VERB
admet-2338	25	16	sfn	sfn	PROPN
admet-2338	25	17	efficacy	efficacy	NOUN
admet-2338	25	18	with	with	ADP
admet-2338	25	19	minimal	minimal	ADJ
admet-2338	25	20	toxicity	toxicity	NOUN
admet-2338	25	21	.	.	PUNCT
admet-2338	26	1	figure	figure	NOUN
admet-2338	26	2	1	1	NUM
admet-2338	26	3	.	.	PUNCT
admet-2338	27	1	chemical	chemical	ADJ
admet-2338	27	2	structure	structure	NOUN
admet-2338	27	3	of	of	ADP
admet-2338	27	4	sorafenib	sorafenib	NOUN
admet-2338	27	5	tosylate	tosylate	VERB
admet-2338	27	6	surface	surface	NOUN
admet-2338	27	7	solid	solid	ADJ
admet-2338	27	8	dispersion	dispersion	NOUN
admet-2338	27	9	(	(	PUNCT
admet-2338	27	10	ssd	ssd	NOUN
admet-2338	27	11	)	)	PUNCT
admet-2338	27	12	techniques	technique	NOUN
admet-2338	27	13	are	be	AUX
admet-2338	27	14	gaining	gain	VERB
admet-2338	27	15	more	more	ADJ
admet-2338	27	16	advantages	advantage	NOUN
admet-2338	27	17	in	in	ADP
admet-2338	27	18	the	the	DET
admet-2338	27	19	pharmaceutical	pharmaceutical	ADJ
admet-2338	27	20	industry	industry	NOUN
admet-2338	27	21	to	to	PART
admet-2338	27	22	improve	improve	VERB
admet-2338	27	23	the	the	DET
admet-2338	27	24	solubility	solubility	NOUN
admet-2338	27	25	and	and	CCONJ
admet-2338	27	26	bioavailability	bioavailability	NOUN
admet-2338	27	27	of	of	ADP
admet-2338	27	28	poorly	poorly	ADV
admet-2338	27	29	water	water	NOUN
admet-2338	27	30	-	-	PUNCT
admet-2338	27	31	soluble	soluble	ADJ
admet-2338	27	32	bioactive	bioactive	NOUN
admet-2338	28	1	[	[	X
admet-2338	28	2	6	6	NUM
admet-2338	28	3	-	-	SYM
admet-2338	28	4	8	8	NUM
admet-2338	28	5	]	]	PUNCT
admet-2338	28	6	.	.	PUNCT
admet-2338	29	1	in	in	ADP
admet-2338	29	2	ssd	ssd	PROPN
admet-2338	29	3	,	,	PUNCT
admet-2338	29	4	the	the	DET
admet-2338	29	5	water	water	NOUN
admet-2338	29	6	-	-	PUNCT
admet-2338	29	7	insoluble	insoluble	ADJ
admet-2338	29	8	pharmaceutical	pharmaceutical	NOUN
admet-2338	29	9	actives	active	NOUN
admet-2338	29	10	are	be	AUX
admet-2338	29	11	adsorbed	adsorb	VERB
admet-2338	29	12	physically	physically	ADV
admet-2338	29	13	or	or	CCONJ
admet-2338	29	14	chemically	chemically	ADV
admet-2338	29	15	on	on	ADP
admet-2338	29	16	the	the	DET
admet-2338	29	17	large	large	ADJ
admet-2338	29	18	surface	surface	NOUN
admet-2338	29	19	area	area	NOUN
admet-2338	29	20	of	of	ADP
admet-2338	29	21	the	the	DET
admet-2338	29	22	water	water	NOUN
admet-2338	29	23	-	-	PUNCT
admet-2338	29	24	insoluble	insoluble	ADJ
admet-2338	29	25	porous	porous	ADJ
admet-2338	29	26	adsorbent	adsorbent	NOUN
admet-2338	29	27	,	,	PUNCT
admet-2338	29	28	such	such	ADJ
admet-2338	29	29	as	as	ADP
admet-2338	29	30	sodium	sodium	NOUN
admet-2338	29	31	starch	starch	NOUN
admet-2338	29	32	glycolate	glycolate	NOUN
admet-2338	29	33	,	,	PUNCT
admet-2338	29	34	potato	potato	NOUN
admet-2338	29	35	starch	starch	NOUN
admet-2338	29	36	,	,	PUNCT
admet-2338	29	37	pregelatinized	pregelatinize	VERB
admet-2338	29	38	starch	starch	NOUN
admet-2338	29	39	,	,	PUNCT
admet-2338	29	40	crospovidone	crospovidone	NOUN
admet-2338	29	41	,	,	PUNCT
admet-2338	29	42	neusilin	neusilin	PROPN
admet-2338	29	43	®	®	NOUN
admet-2338	29	44	us2	us2	PROPN
admet-2338	29	45	,	,	PUNCT
admet-2338	29	46	neusilin	neusilin	NOUN
admet-2338	29	47	®	®	VERB
admet-2338	29	48	uf	uf	PROPN
admet-2338	29	49	,	,	PUNCT
admet-2338	29	50	and	and	CCONJ
admet-2338	29	51	aerosil	aerosil	NOUN
admet-2338	29	52	®	®	NOUN
admet-2338	29	53	200	200	NUM
admet-2338	29	54	,	,	PUNCT
admet-2338	29	55	which	which	PRON
admet-2338	29	56	have	have	VERB
admet-2338	29	57	a	a	DET
admet-2338	29	58	unique	unique	ADJ
admet-2338	29	59	higher	high	ADJ
admet-2338	29	60	affinity	affinity	NOUN
admet-2338	29	61	for	for	ADP
admet-2338	29	62	the	the	DET
admet-2338	29	63	dissolution	dissolution	PROPN
admet-2338	29	64	medium	medium	NOUN
admet-2338	29	65	and	and	CCONJ
admet-2338	29	66	increase	increase	VERB
admet-2338	29	67	the	the	DET
admet-2338	29	68	dissolution	dissolution	NOUN
admet-2338	29	69	kinetics	kinetic	NOUN
admet-2338	29	70	of	of	ADP
admet-2338	29	71	the	the	DET
admet-2338	29	72	adsorbed	adsorb	VERB
admet-2338	29	73	drug	drug	NOUN
admet-2338	29	74	.	.	PUNCT
admet-2338	30	1	neusilin	neusilin	PROPN
admet-2338	30	2	®	®	PROPN
admet-2338	30	3	us2	us2	PROPN
admet-2338	30	4	(	(	PUNCT
admet-2338	30	5	nu2	nu2	PROPN
admet-2338	30	6	)	)	PUNCT
admet-2338	30	7	is	be	AUX
admet-2338	30	8	a	a	DET
admet-2338	30	9	multifunctional	multifunctional	ADJ
admet-2338	30	10	excipient	excipient	NOUN
admet-2338	30	11	that	that	PRON
admet-2338	30	12	solves	solve	VERB
admet-2338	30	13	common	common	ADJ
admet-2338	30	14	problems	problem	NOUN
admet-2338	30	15	associated	associate	VERB
admet-2338	30	16	with	with	ADP
admet-2338	30	17	tableting	tablete	VERB
admet-2338	30	18	by	by	ADP
admet-2338	30	19	facilitating	facilitate	VERB
admet-2338	30	20	a	a	DET
admet-2338	30	21	consistent	consistent	ADJ
admet-2338	30	22	flow	flow	NOUN
admet-2338	30	23	of	of	ADP
admet-2338	30	24	powder	powder	NOUN
admet-2338	30	25	mix	mix	NOUN
admet-2338	30	26	and	and	CCONJ
admet-2338	30	27	optimum	optimum	ADJ
admet-2338	30	28	tablet	tablet	NOUN
admet-2338	30	29	hardness	hardness	ADV
admet-2338	30	30	at	at	ADP
admet-2338	30	31	low	low	ADJ
admet-2338	30	32	compression	compression	NOUN
admet-2338	30	33	forces	force	NOUN
admet-2338	30	34	.	.	PUNCT
admet-2338	31	1	further	far	ADV
admet-2338	31	2	,	,	PUNCT
admet-2338	31	3	nu2	nu2	ADV
admet-2338	31	4	is	be	AUX
admet-2338	31	5	useful	useful	ADJ
admet-2338	31	6	in	in	ADP
admet-2338	31	7	protecting	protect	VERB
admet-2338	31	8	the	the	DET
admet-2338	31	9	active	active	ADJ
admet-2338	31	10	ingredient	ingredient	NOUN
admet-2338	31	11	from	from	ADP
admet-2338	31	12	moisture	moisture	NOUN
admet-2338	31	13	-	-	PUNCT
admet-2338	31	14	related	relate	VERB
admet-2338	31	15	issues	issue	NOUN
admet-2338	31	16	and	and	CCONJ
admet-2338	31	17	enhancing	enhance	VERB
admet-2338	31	18	the	the	DET
admet-2338	31	19	solubility	solubility	NOUN
admet-2338	31	20	of	of	ADP
admet-2338	31	21	poorly	poorly	ADV
admet-2338	31	22	soluble	soluble	ADJ
admet-2338	31	23	apis	apis	ADJ
admet-2338	31	24	.	.	PUNCT
admet-2338	32	1	it	it	PRON
admet-2338	32	2	is	be	AUX
admet-2338	32	3	also	also	ADV
admet-2338	32	4	responsible	responsible	ADJ
admet-2338	32	5	for	for	ADP
admet-2338	32	6	converting	convert	VERB
admet-2338	32	7	oily	oily	ADV
admet-2338	32	8	or	or	CCONJ
admet-2338	32	9	sticky	sticky	ADJ
admet-2338	32	10	apis	apis	NOUN
admet-2338	32	11	into	into	ADP
admet-2338	32	12	free	free	ADJ
admet-2338	32	13	-	-	PUNCT
admet-2338	32	14	flowing	flow	VERB
admet-2338	32	15	powder	powder	NOUN
admet-2338	32	16	.	.	PUNCT
admet-2338	33	1	we	we	PRON
admet-2338	33	2	can	can	AUX
admet-2338	33	3	explore	explore	VERB
admet-2338	33	4	a	a	DET
admet-2338	33	5	synthetic	synthetic	ADJ
admet-2338	33	6	magnesium	magnesium	NOUN
admet-2338	33	7	aluminometasilicate	aluminometasilicate	NOUN
admet-2338	33	8	(	(	PUNCT
admet-2338	33	9	mas	mas	PROPN
admet-2338	33	10	)	)	PUNCT
admet-2338	33	11	with	with	ADP
admet-2338	33	12	exceptional	exceptional	ADJ
admet-2338	33	13	excipient	excipient	ADJ
admet-2338	33	14	properties	property	NOUN
admet-2338	33	15	for	for	ADP
admet-2338	33	16	improved	improved	ADJ
admet-2338	33	17	delivery	delivery	NOUN
admet-2338	33	18	of	of	ADP
admet-2338	33	19	actives	active	NOUN
admet-2338	33	20	and	and	CCONJ
admet-2338	33	21	quality	quality	NOUN
admet-2338	33	22	of	of	ADP
admet-2338	33	23	pharmaceutical	pharmaceutical	ADJ
admet-2338	33	24	preparations	preparation	NOUN
admet-2338	33	25	.	.	PUNCT
admet-2338	34	1	although	although	SCONJ
admet-2338	34	2	chemically	chemically	ADV
admet-2338	34	3	the	the	DET
admet-2338	34	4	same	same	ADJ
admet-2338	34	5	as	as	ADP
admet-2338	34	6	traditional	traditional	ADJ
admet-2338	34	7	crystalline	crystalline	NOUN
admet-2338	34	8	mas	mas	PROPN
admet-2338	34	9	,	,	PUNCT
admet-2338	34	10	nu2	nu2	NOUN
admet-2338	34	11	is	be	AUX
admet-2338	34	12	structurally	structurally	ADV
admet-2338	34	13	and	and	CCONJ
admet-2338	34	14	functionally	functionally	ADV
admet-2338	34	15	a	a	DET
admet-2338	34	16	very	very	ADV
admet-2338	34	17	different	different	ADJ
admet-2338	34	18	product	product	NOUN
admet-2338	34	19	that	that	PRON
admet-2338	34	20	serves	serve	VERB
admet-2338	34	21	a	a	DET
admet-2338	34	22	multitude	multitude	NOUN
admet-2338	34	23	of	of	ADP
admet-2338	34	24	purposes	purpose	NOUN
admet-2338	34	25	when	when	SCONJ
admet-2338	34	26	compared	compare	VERB
admet-2338	34	27	to	to	ADP
admet-2338	34	28	other	other	ADJ
admet-2338	34	29	silicates	silicate	NOUN
admet-2338	34	30	[	[	X
admet-2338	34	31	9	9	NUM
admet-2338	34	32	]	]	PUNCT
admet-2338	34	33	.	.	PUNCT
admet-2338	35	1	further	far	ADV
admet-2338	35	2	,	,	PUNCT
admet-2338	35	3	the	the	DET
admet-2338	35	4	use	use	NOUN
admet-2338	35	5	of	of	ADP
admet-2338	35	6	additional	additional	ADJ
admet-2338	35	7	surfactant	surfactant	NOUN
admet-2338	35	8	in	in	ADP
admet-2338	35	9	ssd	ssd	NOUN
admet-2338	35	10	considerably	considerably	ADV
admet-2338	35	11	improves	improve	VERB
admet-2338	35	12	the	the	DET
admet-2338	35	13	dissolution	dissolution	NOUN
admet-2338	35	14	rate	rate	NOUN
admet-2338	35	15	by	by	ADP
admet-2338	35	16	increasing	increase	VERB
admet-2338	35	17	drug	drug	NOUN
admet-2338	35	18	wettability	wettability	NOUN
admet-2338	35	19	and	and	CCONJ
admet-2338	35	20	a	a	DET
admet-2338	35	21	surface	surface	NOUN
admet-2338	35	22	free	free	ADJ
admet-2338	35	23	energy	energy	NOUN
admet-2338	35	24	[	[	X
admet-2338	35	25	10	10	NUM
admet-2338	35	26	-	-	SYM
admet-2338	35	27	12	12	NUM
admet-2338	35	28	]	]	PUNCT
admet-2338	35	29	.	.	PUNCT
admet-2338	36	1	moreover	moreover	ADV
admet-2338	36	2	,	,	PUNCT
admet-2338	36	3	these	these	DET
admet-2338	36	4	adsorbents	adsorbent	NOUN
admet-2338	36	5	have	have	VERB
admet-2338	36	6	tabletability	tabletability	NOUN
admet-2338	36	7	properties	property	NOUN
admet-2338	36	8	such	such	ADJ
admet-2338	36	9	as	as	ADP
admet-2338	36	10	direct	direct	ADJ
admet-2338	36	11	compressibility	compressibility	NOUN
admet-2338	36	12	and	and	CCONJ
admet-2338	36	13	desirable	desirable	ADJ
admet-2338	36	14	porosity	porosity	NOUN
admet-2338	36	15	[	[	X
admet-2338	36	16	13	13	NUM
admet-2338	36	17	-	-	SYM
admet-2338	36	18	16	16	NUM
admet-2338	36	19	]	]	PUNCT
admet-2338	36	20	.	.	PUNCT
admet-2338	37	1	considering	consider	VERB
admet-2338	37	2	the	the	DET
admet-2338	37	3	advantages	advantage	NOUN
admet-2338	37	4	of	of	ADP
admet-2338	37	5	the	the	DET
admet-2338	37	6	ssd	ssd	NOUN
admet-2338	37	7	technique	technique	NOUN
admet-2338	37	8	,	,	PUNCT
admet-2338	37	9	the	the	DET
admet-2338	37	10	present	present	ADJ
admet-2338	37	11	study	study	NOUN
admet-2338	37	12	aims	aim	VERB
admet-2338	37	13	to	to	PART
admet-2338	37	14	develop	develop	VERB
admet-2338	37	15	surface	surface	NOUN
admet-2338	37	16	solid	solid	ADJ
admet-2338	37	17	dispersion	dispersion	NOUN
admet-2338	37	18	of	of	ADP
admet-2338	37	19	sorafenib	sorafenib	NOUN
admet-2338	37	20	tosylate	tosylate	VERB
admet-2338	37	21	(	(	PUNCT
admet-2338	37	22	sfn	sfn	PROPN
admet-2338	37	23	-	-	PUNCT
admet-2338	37	24	ssd	ssd	NOUN
admet-2338	37	25	)	)	PUNCT
admet-2338	37	26	using	use	VERB
admet-2338	37	27	nu2	nu2	NOUN
admet-2338	37	28	as	as	ADP
admet-2338	37	29	an	an	DET
admet-2338	37	30	adsorbent	adsorbent	NOUN
admet-2338	37	31	and	and	CCONJ
admet-2338	37	32	sodium	sodium	NOUN
admet-2338	37	33	dodecyl	dodecyl	PROPN
admet-2338	37	34	sulphate	sulphate	NOUN
admet-2338	37	35	(	(	PUNCT
admet-2338	37	36	sds	sds	PROPN
admet-2338	37	37	)	)	PUNCT
admet-2338	37	38	as	as	ADP
admet-2338	37	39	a	a	DET
admet-2338	37	40	surfactant	surfactant	NOUN
admet-2338	37	41	using	use	VERB
admet-2338	37	42	a	a	DET
admet-2338	37	43	solvent	solvent	ADJ
admet-2338	37	44	evaporation	evaporation	NOUN
admet-2338	37	45	technique	technique	NOUN
admet-2338	37	46	for	for	ADP
admet-2338	37	47	improving	improve	VERB
admet-2338	37	48	sfn	sfn	PROPN
admet-2338	37	49	solubility	solubility	NOUN
admet-2338	37	50	,	,	PUNCT
admet-2338	37	51	bioavailability	bioavailability	NOUN
admet-2338	37	52	,	,	PUNCT
admet-2338	37	53	and	and	CCONJ
admet-2338	37	54	therapeutic	therapeutic	ADJ
admet-2338	37	55	efficacy	efficacy	NOUN
admet-2338	37	56	.	.	PUNCT
admet-2338	38	1	initially	initially	ADV
admet-2338	38	2	,	,	PUNCT
admet-2338	38	3	the	the	DET
admet-2338	38	4	screening	screening	NOUN
admet-2338	38	5	of	of	ADP
admet-2338	38	6	the	the	DET
admet-2338	38	7	adsorbents	adsorbent	NOUN
admet-2338	38	8	and	and	CCONJ
admet-2338	38	9	surfactants	surfactant	NOUN
admet-2338	38	10	was	be	AUX
admet-2338	38	11	based	base	VERB
admet-2338	38	12	on	on	ADP
admet-2338	38	13	assessing	assess	VERB
admet-2338	38	14	the	the	DET
admet-2338	38	15	solubility	solubility	NOUN
admet-2338	38	16	improvement	improvement	NOUN
admet-2338	38	17	of	of	ADP
admet-2338	38	18	sfn	sfn	PROPN
admet-2338	38	19	.	.	PUNCT
admet-2338	39	1	further	far	ADV
admet-2338	39	2	,	,	PUNCT
admet-2338	39	3	the	the	DET
admet-2338	39	4	design	design	NOUN
admet-2338	39	5	of	of	ADP
admet-2338	39	6	experiment	experiment	NOUN
admet-2338	39	7	(	(	PUNCT
admet-2338	39	8	doe	doe	NOUN
admet-2338	39	9	)	)	PUNCT
admet-2338	39	10	was	be	AUX
admet-2338	39	11	opted	opt	VERB
admet-2338	39	12	to	to	PART
admet-2338	39	13	optimize	optimize	VERB
admet-2338	39	14	the	the	DET
admet-2338	39	15	formulation	formulation	NOUN
admet-2338	39	16	using	use	VERB
admet-2338	39	17	32	32	NUM
admet-2338	39	18	factorial	factorial	ADJ
admet-2338	39	19	designs	design	NOUN
admet-2338	39	20	(	(	PUNCT
admet-2338	39	21	design	design	NOUN
admet-2338	39	22	expert	expert	NOUN
admet-2338	39	23	11	11	NUM
admet-2338	39	24	,	,	PUNCT
admet-2338	39	25	stat	stat	NOUN
admet-2338	39	26	-	-	PUNCT
admet-2338	39	27	ease	ease	NOUN
admet-2338	39	28	)	)	PUNCT
admet-2338	40	1	[	[	X
admet-2338	40	2	17,18	17,18	NUM
admet-2338	40	3	]	]	PUNCT
admet-2338	40	4	.	.	PUNCT
admet-2338	41	1	the	the	DET
admet-2338	41	2	optimized	optimize	VERB
admet-2338	41	3	sfn	sfn	PROPN
admet-2338	41	4	-	-	PUNCT
admet-2338	41	5	ssd	ssd	NOUN
admet-2338	41	6	was	be	AUX
admet-2338	41	7	evaluated	evaluate	VERB
admet-2338	41	8	in	in	ADP
admet-2338	41	9	terms	term	NOUN
admet-2338	41	10	of	of	ADP
admet-2338	41	11	drug	drug	NOUN
admet-2338	41	12	content	content	NOUN
admet-2338	41	13	,	,	PUNCT
admet-2338	41	14	solubility	solubility	NOUN
admet-2338	41	15	,	,	PUNCT
admet-2338	41	16	ftir	ftir	PROPN
admet-2338	41	17	,	,	PUNCT
admet-2338	41	18	dsc	dsc	PROPN
admet-2338	41	19	,	,	PUNCT
admet-2338	41	20	sem	sem	NOUN
admet-2338	41	21	,	,	PUNCT
admet-2338	41	22	and	and	CCONJ
admet-2338	41	23	in	in	ADP
admet-2338	41	24	-	-	PUNCT
admet-2338	41	25	vivo	vivo	NOUN
admet-2338	41	26	pharmacokinetics	pharmacokinetic	NOUN
admet-2338	41	27	studies	study	NOUN
admet-2338	41	28	in	in	ADP
admet-2338	41	29	wistar	wistar	PROPN
admet-2338	41	30	rats	rat	NOUN
admet-2338	41	31	.	.	PUNCT
admet-2338	42	1	moreover	moreover	ADV
admet-2338	42	2	,	,	PUNCT
admet-2338	42	3	the	the	DET
admet-2338	42	4	optimized	optimize	VERB
admet-2338	42	5	sfn	sfn	PROPN
admet-2338	42	6	-	-	PUNCT
admet-2338	42	7	ssd	ssd	NOUN
admet-2338	42	8	was	be	AUX
admet-2338	42	9	converted	convert	VERB
admet-2338	42	10	into	into	ADP
admet-2338	42	11	immediate	immediate	ADJ
admet-2338	42	12	-	-	PUNCT
admet-2338	42	13	release	release	NOUN
admet-2338	42	14	tablets	tablet	NOUN
admet-2338	42	15	using	use	VERB
admet-2338	42	16	conventional	conventional	ADJ
admet-2338	42	17	excipients	excipient	NOUN
admet-2338	42	18	and	and	CCONJ
admet-2338	42	19	evaluated	evaluate	VERB
admet-2338	42	20	for	for	ADP
admet-2338	42	21	pharmaceutical	pharmaceutical	ADJ
admet-2338	42	22	properties	property	NOUN
admet-2338	42	23	.	.	PUNCT
admet-2338	43	1	admet	admet	PROPN
admet-2338	43	2	&	&	CCONJ
admet-2338	43	3	dmpk	dmpk	PROPN
admet-2338	43	4	12(4	12(4	PROPN
admet-2338	43	5	)	)	PUNCT
admet-2338	43	6	(	(	PUNCT
admet-2338	43	7	2024	2024	NUM
admet-2338	43	8	)	)	PUNCT
admet-2338	43	9	687	687	NUM
admet-2338	43	10	-	-	SYM
admet-2338	43	11	702	702	NUM
admet-2338	43	12	neusilin	neusilin	PROPN
admet-2338	43	13	us2	us2	PROPN
admet-2338	43	14	based	base	VERB
admet-2338	43	15	surface	surface	NOUN
admet-2338	43	16	solid	solid	ADJ
admet-2338	43	17	dispersion	dispersion	NOUN
admet-2338	43	18	of	of	ADP
admet-2338	43	19	sorafenib	sorafenib	NOUN
admet-2338	43	20	tosylate	tosylate	VERB
admet-2338	43	21	doi	doi	NOUN
admet-2338	43	22	:	:	PUNCT
admet-2338	43	23	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	ADJ
admet-2338	43	24	689	689	NUM
admet-2338	43	25	materials	material	NOUN
admet-2338	43	26	and	and	CCONJ
admet-2338	43	27	methods	method	NOUN
admet-2338	43	28	materials	material	NOUN
admet-2338	43	29	sorafenib	sorafenib	NOUN
admet-2338	43	30	tosylate	tosylate	VERB
admet-2338	43	31	(	(	PUNCT
admet-2338	43	32	≥99	≥99	NUM
admet-2338	43	33	%	%	NOUN
admet-2338	43	34	)	)	PUNCT
admet-2338	43	35	was	be	AUX
admet-2338	43	36	kindly	kindly	ADV
admet-2338	43	37	provided	provide	VERB
admet-2338	43	38	by	by	ADP
admet-2338	43	39	cipla	cipla	PROPN
admet-2338	43	40	ltd	ltd	PROPN
admet-2338	43	41	.	.	PROPN
admet-2338	43	42	mumbai	mumbai	PROPN
admet-2338	43	43	,	,	PUNCT
admet-2338	43	44	india	india	PROPN
admet-2338	43	45	.	.	PUNCT
admet-2338	44	1	neusilin	neusilin	PROPN
admet-2338	44	2	®	®	NOUN
admet-2338	44	3	us2(≥99.9	us2(≥99.9	ADP
admet-2338	44	4	%	%	INTJ
admet-2338	44	5	)	)	PUNCT
admet-2338	44	6	was	be	AUX
admet-2338	44	7	received	receive	VERB
admet-2338	44	8	as	as	ADP
admet-2338	44	9	a	a	DET
admet-2338	44	10	gift	gift	NOUN
admet-2338	44	11	sample	sample	NOUN
admet-2338	44	12	from	from	ADP
admet-2338	44	13	fuji	fuji	PROPN
admet-2338	44	14	chemical	chemical	PROPN
admet-2338	44	15	industries	industries	PROPN
admet-2338	44	16	co.	co.	PROPN
admet-2338	44	17	,	,	PUNCT
admet-2338	44	18	ltd	ltd	PROPN
admet-2338	44	19	,	,	PUNCT
admet-2338	44	20	japan	japan	PROPN
admet-2338	44	21	.	.	PUNCT
admet-2338	45	1	sodium	sodium	PROPN
admet-2338	45	2	dodecyl	dodecyl	PROPN
admet-2338	45	3	sulphate	sulphate	NOUN
admet-2338	45	4	(	(	PUNCT
admet-2338	45	5	99	99	NUM
admet-2338	45	6	%	%	NOUN
admet-2338	45	7	)	)	PUNCT
admet-2338	45	8	was	be	AUX
admet-2338	45	9	purchased	purchase	VERB
admet-2338	45	10	from	from	ADP
admet-2338	45	11	merck	merck	PROPN
admet-2338	45	12	specialties	specialty	NOUN
admet-2338	45	13	co	co	VERB
admet-2338	45	14	ltd	ltd	PROPN
admet-2338	45	15	,	,	PUNCT
admet-2338	45	16	mumbai	mumbai	PROPN
admet-2338	45	17	,	,	PUNCT
admet-2338	45	18	india	india	PROPN
admet-2338	45	19	.	.	PUNCT
admet-2338	46	1	hplc	hplc	PROPN
admet-2338	46	2	grade	grade	NOUN
admet-2338	46	3	methanol	methanol	NOUN
admet-2338	46	4	(	(	PUNCT
admet-2338	46	5	≥99.9	≥99.9	PROPN
admet-2338	46	6	%	%	INTJ
admet-2338	46	7	)	)	PUNCT
admet-2338	46	8	and	and	CCONJ
admet-2338	46	9	acetonitrile	acetonitrile	NOUN
admet-2338	46	10	(	(	PUNCT
admet-2338	46	11	≥99.9	≥99.9	PROPN
admet-2338	46	12	%	%	INTJ
admet-2338	46	13	)	)	PUNCT
admet-2338	46	14	were	be	AUX
admet-2338	46	15	purchased	purchase	VERB
admet-2338	46	16	from	from	ADP
admet-2338	46	17	ranikem	ranikem	PROPN
admet-2338	46	18	,	,	PUNCT
admet-2338	46	19	avantor	avantor	NOUN
admet-2338	46	20	,	,	PUNCT
admet-2338	46	21	india	india	PROPN
admet-2338	46	22	.	.	PUNCT
admet-2338	47	1	all	all	DET
admet-2338	47	2	other	other	ADJ
admet-2338	47	3	chemicals	chemical	NOUN
admet-2338	47	4	and	and	CCONJ
admet-2338	47	5	solvents	solvent	NOUN
admet-2338	47	6	used	use	VERB
admet-2338	47	7	in	in	ADP
admet-2338	47	8	this	this	DET
admet-2338	47	9	research	research	NOUN
admet-2338	47	10	were	be	AUX
admet-2338	47	11	of	of	ADP
admet-2338	47	12	analytical	analytical	ADJ
admet-2338	47	13	grade	grade	NOUN
admet-2338	47	14	and	and	CCONJ
admet-2338	47	15	water	water	NOUN
admet-2338	47	16	used	use	VERB
admet-2338	47	17	was	be	AUX
admet-2338	47	18	millipore	millipore	NOUN
admet-2338	47	19	water	water	NOUN
admet-2338	47	20	.	.	PUNCT
admet-2338	48	1	methods	method	NOUN
admet-2338	48	2	screening	screen	VERB
admet-2338	48	3	of	of	ADP
admet-2338	48	4	solvents	solvent	NOUN
admet-2338	48	5	the	the	DET
admet-2338	48	6	saturation	saturation	NOUN
admet-2338	48	7	solubility	solubility	NOUN
admet-2338	48	8	of	of	ADP
admet-2338	48	9	sfn	sfn	PROPN
admet-2338	48	10	was	be	AUX
admet-2338	48	11	analysed	analyse	VERB
admet-2338	48	12	by	by	ADP
admet-2338	48	13	adding	add	VERB
admet-2338	48	14	an	an	DET
admet-2338	48	15	excess	excess	ADJ
admet-2338	48	16	amount	amount	NOUN
admet-2338	48	17	of	of	ADP
admet-2338	48	18	sfn	sfn	NOUN
admet-2338	48	19	in	in	ADP
admet-2338	48	20	2	2	NUM
admet-2338	48	21	ml	ml	NOUN
admet-2338	48	22	of	of	ADP
admet-2338	48	23	water	water	NOUN
admet-2338	48	24	,	,	PUNCT
admet-2338	48	25	0.1n	0.1n	PROPN
admet-2338	48	26	hcl	hcl	PROPN
admet-2338	48	27	,	,	PUNCT
admet-2338	48	28	phosphate	phosphate	ADJ
admet-2338	48	29	buffer	buffer	NOUN
admet-2338	48	30	ph	ph	VERB
admet-2338	48	31	6.8	6.8	NUM
admet-2338	48	32	,	,	PUNCT
admet-2338	48	33	methanol	methanol	NOUN
admet-2338	48	34	,	,	PUNCT
admet-2338	48	35	ethanol	ethanol	NOUN
admet-2338	48	36	and	and	CCONJ
admet-2338	48	37	dimethyl	dimethyl	NOUN
admet-2338	48	38	sulfoxide	sulfoxide	NOUN
admet-2338	48	39	(	(	PUNCT
admet-2338	48	40	dmso	dmso	NOUN
admet-2338	48	41	)	)	PUNCT
admet-2338	48	42	solvents	solvent	NOUN
admet-2338	48	43	in	in	ADP
admet-2338	48	44	eppendorf	eppendorf	NOUN
admet-2338	48	45	tube	tube	NOUN
admet-2338	48	46	and	and	CCONJ
admet-2338	48	47	allowed	allow	VERB
admet-2338	48	48	to	to	PART
admet-2338	48	49	equilibrate	equilibrate	VERB
admet-2338	48	50	on	on	ADP
admet-2338	48	51	a	a	DET
admet-2338	48	52	mechanical	mechanical	ADJ
admet-2338	48	53	shaker	shaker	NOUN
admet-2338	48	54	for	for	ADP
admet-2338	48	55	24	24	NUM
admet-2338	48	56	hours	hour	NOUN
admet-2338	48	57	.	.	PUNCT
admet-2338	49	1	the	the	DET
admet-2338	49	2	dispersion	dispersion	NOUN
admet-2338	49	3	was	be	AUX
admet-2338	49	4	filtered	filter	VERB
admet-2338	49	5	using	use	VERB
admet-2338	49	6	a	a	DET
admet-2338	49	7	0.45	0.45	NUM
admet-2338	49	8	µm	µm	ADP
admet-2338	49	9	syringe	syringe	NOUN
admet-2338	49	10	filter	filter	NOUN
admet-2338	49	11	,	,	PUNCT
admet-2338	49	12	and	and	CCONJ
admet-2338	49	13	the	the	DET
admet-2338	49	14	amount	amount	NOUN
admet-2338	49	15	of	of	ADP
admet-2338	49	16	sfn	sfn	PROPN
admet-2338	49	17	in	in	ADP
admet-2338	49	18	each	each	DET
admet-2338	49	19	solvent	solvent	NOUN
admet-2338	49	20	was	be	AUX
admet-2338	49	21	determined	determine	VERB
admet-2338	49	22	by	by	ADP
admet-2338	49	23	uv	uv	NOUN
admet-2338	49	24	spectrometry	spectrometry	NOUN
admet-2338	49	25	at	at	ADP
admet-2338	49	26	λmax	λmax	NOUN
admet-2338	49	27	of	of	ADP
admet-2338	49	28	265	265	NUM
admet-2338	49	29	nm	nm	NOUN
admet-2338	49	30	.	.	PUNCT
admet-2338	50	1	the	the	DET
admet-2338	50	2	solvent	solvent	NOUN
admet-2338	50	3	with	with	ADP
admet-2338	50	4	the	the	DET
admet-2338	50	5	maximum	maximum	ADJ
admet-2338	50	6	drug	drug	NOUN
admet-2338	50	7	solubility	solubility	NOUN
admet-2338	50	8	was	be	AUX
admet-2338	50	9	selected	select	VERB
admet-2338	50	10	to	to	PART
admet-2338	50	11	prepare	prepare	VERB
admet-2338	50	12	ssd	ssd	NOUN
admet-2338	50	13	[	[	X
admet-2338	50	14	14	14	NUM
admet-2338	50	15	]	]	PUNCT
admet-2338	50	16	.	.	PUNCT
admet-2338	51	1	screening	screen	VERB
admet-2338	51	2	of	of	ADP
admet-2338	51	3	adsorbents	adsorbent	NOUN
admet-2338	51	4	screening	screen	VERB
admet-2338	51	5	of	of	ADP
admet-2338	51	6	adsorbents	adsorbent	NOUN
admet-2338	51	7	was	be	AUX
admet-2338	51	8	done	do	VERB
admet-2338	51	9	based	base	VERB
admet-2338	51	10	on	on	ADP
admet-2338	51	11	improvement	improvement	NOUN
admet-2338	51	12	in	in	ADP
admet-2338	51	13	sfn	sfn	PROPN
admet-2338	51	14	solubility	solubility	NOUN
admet-2338	51	15	.	.	PUNCT
admet-2338	52	1	three	three	NUM
admet-2338	52	2	silica	silica	NOUN
admet-2338	52	3	-	-	PUNCT
admet-2338	52	4	based	base	VERB
admet-2338	52	5	porous	porous	ADJ
admet-2338	52	6	adsorbents	adsorbent	NOUN
admet-2338	52	7	,	,	PUNCT
admet-2338	52	8	aerosil	aerosil	NOUN
admet-2338	52	9	200	200	NUM
admet-2338	52	10	,	,	PUNCT
admet-2338	52	11	rxcipients	rxcipient	NOUN
admet-2338	52	12	gl	gl	X
admet-2338	52	13	100	100	NUM
admet-2338	52	14	,	,	PUNCT
admet-2338	52	15	and	and	CCONJ
admet-2338	52	16	nu2	nu2	ADV
admet-2338	52	17	,	,	PUNCT
admet-2338	52	18	were	be	AUX
admet-2338	52	19	selected	select	VERB
admet-2338	52	20	.	.	PUNCT
admet-2338	53	1	sfn	sfn	PROPN
admet-2338	53	2	was	be	AUX
admet-2338	53	3	dissolved	dissolve	VERB
admet-2338	53	4	in	in	ADP
admet-2338	53	5	0.2	0.2	NUM
admet-2338	53	6	ml	ml	NOUN
admet-2338	53	7	of	of	ADP
admet-2338	53	8	dmso	dmso	NOUN
admet-2338	53	9	and	and	CCONJ
admet-2338	53	10	1	1	NUM
admet-2338	53	11	ml	ml	NOUN
admet-2338	53	12	of	of	ADP
admet-2338	53	13	ethanol	ethanol	NOUN
admet-2338	53	14	,	,	PUNCT
admet-2338	53	15	in	in	ADP
admet-2338	53	16	which	which	PRON
admet-2338	53	17	selected	select	VERB
admet-2338	53	18	adsorbent	adsorbent	NOUN
admet-2338	53	19	in	in	ADP
admet-2338	53	20	the	the	DET
admet-2338	53	21	ratio	ratio	NOUN
admet-2338	53	22	of	of	ADP
admet-2338	53	23	1:2	1:2	NUM
admet-2338	53	24	(	(	PUNCT
admet-2338	53	25	drug	drug	NOUN
admet-2338	53	26	:	:	PUNCT
admet-2338	53	27	adsorbent	adsorbent	NOUN
admet-2338	53	28	)	)	PUNCT
admet-2338	53	29	was	be	AUX
admet-2338	53	30	added	add	VERB
admet-2338	53	31	gradually	gradually	ADV
admet-2338	53	32	with	with	ADP
admet-2338	53	33	continuous	continuous	ADJ
admet-2338	53	34	trituration	trituration	NOUN
admet-2338	53	35	.	.	PUNCT
admet-2338	54	1	the	the	DET
admet-2338	54	2	mixture	mixture	NOUN
admet-2338	54	3	was	be	AUX
admet-2338	54	4	completely	completely	ADV
admet-2338	54	5	dried	dry	VERB
admet-2338	54	6	under	under	ADP
admet-2338	54	7	vacuum	vacuum	NOUN
admet-2338	54	8	at	at	ADP
admet-2338	54	9	60	60	NUM
admet-2338	54	10	°	°	NOUN
admet-2338	54	11	c	c	NOUN
admet-2338	54	12	.	.	PUNCT
admet-2338	55	1	the	the	DET
admet-2338	55	2	improved	improved	ADJ
admet-2338	55	3	solubility	solubility	NOUN
admet-2338	55	4	of	of	ADP
admet-2338	55	5	sfn	sfn	PROPN
admet-2338	55	6	by	by	ADP
admet-2338	55	7	each	each	DET
admet-2338	55	8	adsorbent	adsorbent	NOUN
admet-2338	55	9	was	be	AUX
admet-2338	55	10	determined	determine	VERB
admet-2338	55	11	by	by	ADP
admet-2338	55	12	adding	add	VERB
admet-2338	55	13	an	an	DET
admet-2338	55	14	excess	excess	ADJ
admet-2338	55	15	amount	amount	NOUN
admet-2338	55	16	of	of	ADP
admet-2338	55	17	dispersion	dispersion	NOUN
admet-2338	55	18	in	in	ADP
admet-2338	55	19	double	double	ADJ
admet-2338	55	20	distilled	distil	VERB
admet-2338	55	21	water	water	NOUN
admet-2338	55	22	(	(	PUNCT
admet-2338	55	23	ddw	ddw	NOUN
admet-2338	55	24	)	)	PUNCT
admet-2338	55	25	.	.	PUNCT
admet-2338	56	1	screening	screen	VERB
admet-2338	56	2	of	of	ADP
admet-2338	56	3	surfactant	surfactant	NOUN
admet-2338	56	4	the	the	DET
admet-2338	56	5	surfactant	surfactant	NOUN
admet-2338	56	6	was	be	AUX
admet-2338	56	7	selected	select	VERB
admet-2338	56	8	depending	depend	VERB
admet-2338	56	9	on	on	ADP
admet-2338	56	10	the	the	DET
admet-2338	56	11	highest	high	ADJ
admet-2338	56	12	solubility	solubility	NOUN
admet-2338	56	13	of	of	ADP
admet-2338	56	14	sfn	sfn	PROPN
admet-2338	56	15	in	in	ADP
admet-2338	56	16	different	different	ADJ
admet-2338	56	17	concentration	concentration	NOUN
admet-2338	56	18	surfactant	surfactant	NOUN
admet-2338	56	19	solutions	solution	NOUN
admet-2338	56	20	.	.	PUNCT
admet-2338	57	1	briefly	briefly	NOUN
admet-2338	57	2	,	,	PUNCT
admet-2338	57	3	an	an	DET
admet-2338	57	4	excessive	excessive	ADJ
admet-2338	57	5	amount	amount	NOUN
admet-2338	57	6	of	of	ADP
admet-2338	57	7	sfn	sfn	PROPN
admet-2338	57	8	was	be	AUX
admet-2338	57	9	added	add	VERB
admet-2338	57	10	to	to	ADP
admet-2338	57	11	1	1	NUM
admet-2338	57	12	ml	ml	NOUN
admet-2338	57	13	of	of	ADP
admet-2338	57	14	1	1	NUM
admet-2338	57	15	%	%	NOUN
admet-2338	57	16	w	w	PROPN
admet-2338	57	17	/	/	SYM
admet-2338	57	18	v	v	NOUN
admet-2338	57	19	solution	solution	NOUN
admet-2338	57	20	of	of	ADP
admet-2338	57	21	selected	select	VERB
admet-2338	57	22	poloxamer	poloxamer	NOUN
admet-2338	57	23	407	407	NUM
admet-2338	57	24	,	,	PUNCT
admet-2338	57	25	poloxamer	poloxamer	NOUN
admet-2338	57	26	188	188	NUM
admet-2338	57	27	,	,	PUNCT
admet-2338	57	28	gelucire	gelucire	VERB
admet-2338	57	29	50/13	50/13	NUM
admet-2338	57	30	,	,	PUNCT
admet-2338	57	31	sds	sds	NOUN
admet-2338	57	32	,	,	PUNCT
admet-2338	57	33	transcutol	transcutol	ADJ
admet-2338	57	34	p	p	NOUN
admet-2338	57	35	and	and	CCONJ
admet-2338	57	36	labrasol	labrasol	ADJ
admet-2338	57	37	surfactants	surfactant	NOUN
admet-2338	57	38	in	in	ADP
admet-2338	57	39	eppendorf	eppendorf	PROPN
admet-2338	57	40	tube	tube	NOUN
admet-2338	58	1	[	[	X
admet-2338	58	2	19	19	NUM
admet-2338	58	3	]	]	PUNCT
admet-2338	58	4	.	.	PUNCT
admet-2338	59	1	each	each	DET
admet-2338	59	2	dispersion	dispersion	NOUN
admet-2338	59	3	was	be	AUX
admet-2338	59	4	shaken	shake	VERB
admet-2338	59	5	continuously	continuously	ADV
admet-2338	59	6	for	for	ADP
admet-2338	59	7	24	24	NUM
admet-2338	59	8	hours	hour	NOUN
admet-2338	59	9	on	on	ADP
admet-2338	59	10	a	a	DET
admet-2338	59	11	mechanical	mechanical	ADJ
admet-2338	59	12	shaker	shaker	NOUN
admet-2338	59	13	,	,	PUNCT
admet-2338	59	14	centrifuged	centrifuge	VERB
admet-2338	59	15	for	for	ADP
admet-2338	59	16	15	15	NUM
admet-2338	59	17	min	min	NOUN
admet-2338	59	18	at	at	ADP
admet-2338	59	19	15000	15000	NUM
admet-2338	59	20	rpm	rpm	NOUN
admet-2338	59	21	and	and	CCONJ
admet-2338	59	22	filtered	filter	VERB
admet-2338	59	23	.	.	PUNCT
admet-2338	60	1	the	the	DET
admet-2338	60	2	sfn	sfn	PROPN
admet-2338	60	3	concentration	concentration	NOUN
admet-2338	60	4	was	be	AUX
admet-2338	60	5	determined	determine	VERB
admet-2338	60	6	in	in	ADP
admet-2338	60	7	supernatant	supernatant	NOUN
admet-2338	60	8	using	use	VERB
admet-2338	60	9	uv	uv	NOUN
admet-2338	60	10	-	-	PUNCT
admet-2338	60	11	spectrometry	spectrometry	NOUN
admet-2338	60	12	at	at	ADP
admet-2338	60	13	λmax	λmax	NOUN
admet-2338	60	14	of	of	ADP
admet-2338	60	15	265	265	NUM
admet-2338	60	16	nm	nm	NOUN
admet-2338	60	17	.	.	PUNCT
admet-2338	61	1	preparation	preparation	NOUN
admet-2338	61	2	and	and	CCONJ
admet-2338	61	3	optimization	optimization	NOUN
admet-2338	61	4	of	of	ADP
admet-2338	61	5	sfn	sfn	PROPN
admet-2338	61	6	-	-	PUNCT
admet-2338	61	7	ssd	ssd	NOUN
admet-2338	61	8	the	the	DET
admet-2338	61	9	ssd	ssd	NOUN
admet-2338	61	10	of	of	ADP
admet-2338	61	11	sfn	sfn	PROPN
admet-2338	61	12	was	be	AUX
admet-2338	61	13	prepared	prepare	VERB
admet-2338	61	14	using	use	VERB
admet-2338	61	15	a	a	DET
admet-2338	61	16	solvent	solvent	ADJ
admet-2338	61	17	evaporation	evaporation	NOUN
admet-2338	61	18	technique	technique	NOUN
admet-2338	61	19	.	.	PUNCT
admet-2338	62	1	from	from	ADP
admet-2338	62	2	the	the	DET
admet-2338	62	3	above	above	ADJ
admet-2338	62	4	screening	screen	VERB
admet-2338	62	5	analysis	analysis	NOUN
admet-2338	62	6	,	,	PUNCT
admet-2338	62	7	the	the	DET
admet-2338	62	8	nu2	nu2	NOUN
admet-2338	62	9	as	as	ADP
admet-2338	62	10	an	an	DET
admet-2338	62	11	adsorbent	adsorbent	NOUN
admet-2338	62	12	,	,	PUNCT
admet-2338	62	13	sds	sds	NOUN
admet-2338	62	14	as	as	ADP
admet-2338	62	15	a	a	DET
admet-2338	62	16	surfactant	surfactant	NOUN
admet-2338	62	17	and	and	CCONJ
admet-2338	62	18	dmso	dmso	NOUN
admet-2338	62	19	as	as	SCONJ
admet-2338	62	20	a	a	DET
admet-2338	62	21	solvent	solvent	NOUN
admet-2338	62	22	were	be	AUX
admet-2338	62	23	selected	select	VERB
admet-2338	62	24	to	to	PART
admet-2338	62	25	prepare	prepare	VERB
admet-2338	62	26	ssd	ssd	NOUN
admet-2338	62	27	-	-	PUNCT
admet-2338	62	28	sfn	sfn	NOUN
admet-2338	62	29	.	.	PUNCT
admet-2338	63	1	the	the	DET
admet-2338	63	2	concentration	concentration	NOUN
admet-2338	63	3	of	of	ADP
admet-2338	63	4	nu2	nu2	NOUN
admet-2338	63	5	and	and	CCONJ
admet-2338	63	6	sds	sds	PROPN
admet-2338	63	7	were	be	AUX
admet-2338	63	8	optimized	optimize	VERB
admet-2338	63	9	by	by	ADP
admet-2338	63	10	32	32	NUM
admet-2338	63	11	factorial	factorial	ADJ
admet-2338	63	12	designs	design	NOUN
admet-2338	63	13	using	use	VERB
admet-2338	63	14	design	design	NOUN
admet-2338	63	15	-	-	PUNCT
admet-2338	63	16	expert	expert	NOUN
admet-2338	63	17	®	®	NOUN
admet-2338	63	18	software	software	NOUN
admet-2338	63	19	version	version	NOUN
admet-2338	63	20	11	11	NUM
admet-2338	63	21	,	,	PUNCT
admet-2338	63	22	stat	stat	NOUN
admet-2338	63	23	-	-	PUNCT
admet-2338	63	24	ease	ease	NOUN
admet-2338	63	25	,	,	PUNCT
admet-2338	63	26	usa	usa	PROPN
admet-2338	63	27	.	.	PROPN
admet-2338	63	28	as	as	SCONJ
admet-2338	63	29	shown	show	VERB
admet-2338	63	30	in	in	ADP
admet-2338	63	31	table	table	NOUN
admet-2338	63	32	1	1	NUM
admet-2338	63	33	,	,	PUNCT
admet-2338	63	34	the	the	DET
admet-2338	63	35	concentration	concentration	NOUN
admet-2338	63	36	of	of	ADP
admet-2338	63	37	nu2	nu2	NOUN
admet-2338	63	38	and	and	CCONJ
admet-2338	63	39	sds	sds	PROPN
admet-2338	63	40	were	be	AUX
admet-2338	63	41	selected	select	VERB
admet-2338	63	42	as	as	ADP
admet-2338	63	43	an	an	DET
admet-2338	63	44	independent	independent	ADJ
admet-2338	63	45	variable	variable	NOUN
admet-2338	63	46	and	and	CCONJ
admet-2338	63	47	the	the	DET
admet-2338	63	48	solubility	solubility	NOUN
admet-2338	63	49	of	of	ADP
admet-2338	63	50	sfn	sfn	PROPN
admet-2338	63	51	as	as	ADP
admet-2338	63	52	a	a	DET
admet-2338	63	53	dependent	dependent	ADJ
admet-2338	63	54	variable	variable	NOUN
admet-2338	64	1	[	[	X
admet-2338	64	2	20,21	20,21	NUM
admet-2338	64	3	]	]	PUNCT
admet-2338	64	4	.	.	PUNCT
admet-2338	65	1	a	a	DET
admet-2338	65	2	total	total	NOUN
admet-2338	65	3	of	of	ADP
admet-2338	65	4	nine	nine	NUM
admet-2338	65	5	runs	run	NOUN
admet-2338	65	6	were	be	AUX
admet-2338	65	7	obtained	obtain	VERB
admet-2338	65	8	by	by	ADP
admet-2338	65	9	design	design	NOUN
admet-2338	65	10	expert	expert	NOUN
admet-2338	65	11	11	11	NUM
admet-2338	65	12	.	.	PUNCT
admet-2338	66	1	for	for	ADP
admet-2338	66	2	each	each	DET
admet-2338	66	3	run	run	NOUN
admet-2338	66	4	,	,	PUNCT
admet-2338	66	5	sfn	sfn	PROPN
admet-2338	66	6	concentration	concentration	NOUN
admet-2338	66	7	was	be	AUX
admet-2338	66	8	constant	constant	ADJ
admet-2338	66	9	,	,	PUNCT
admet-2338	66	10	i.e.	i.e.	X
admet-2338	66	11	50	50	NUM
admet-2338	66	12	mg	mg	NOUN
admet-2338	66	13	.	.	PUNCT
admet-2338	67	1	equation	equation	NOUN
admet-2338	67	2	(	(	PUNCT
admet-2338	67	3	1	1	X
admet-2338	67	4	)	)	PUNCT
admet-2338	67	5	was	be	AUX
admet-2338	67	6	obtained	obtain	VERB
admet-2338	67	7	:	:	PUNCT
admet-2338	68	1	y	y	NOUN
admet-2338	68	2	=	=	PUNCT
admet-2338	68	3	0	0	NOUN
admet-2338	69	1	+	+	CCONJ
admet-2338	69	2	1x1	1x1	NOUN
admet-2338	69	3	+	+	CCONJ
admet-2338	69	4	2x2	2x2	NOUN
admet-2338	69	5	+	+	CCONJ
admet-2338	69	6	11x1x1	11x1x1	PROPN
admet-2338	69	7	+	+	CCONJ
admet-2338	69	8	22x2x2	22x2x2	X
admet-2338	69	9	+	+	CCONJ
admet-2338	69	10	12x1x2	12x1x2	SYM
admet-2338	69	11	(	(	PUNCT
admet-2338	69	12	1	1	X
admet-2338	69	13	)	)	PUNCT
admet-2338	69	14	where	where	SCONJ
admet-2338	69	15	y	y	PROPN
admet-2338	69	16	is	be	AUX
admet-2338	69	17	the	the	DET
admet-2338	69	18	measured	measured	ADJ
admet-2338	69	19	response	response	NOUN
admet-2338	69	20	,	,	PUNCT
admet-2338	69	21	x	x	PRON
admet-2338	69	22	is	be	AUX
admet-2338	69	23	the	the	DET
admet-2338	69	24	level	level	NOUN
admet-2338	69	25	of	of	ADP
admet-2338	69	26	factors	factor	NOUN
admet-2338	69	27	and	and	CCONJ
admet-2338	69	28	𝛽	𝛽	NOUN
admet-2338	69	29	is	be	AUX
admet-2338	69	30	the	the	DET
admet-2338	69	31	regression	regression	NOUN
admet-2338	69	32	coefficient	coefficient	NOUN
admet-2338	69	33	and	and	CCONJ
admet-2338	69	34	x1	x1	PROPN
admet-2338	69	35	and	and	CCONJ
admet-2338	69	36	x2	x2	PROPN
admet-2338	69	37	indicate	indicate	VERB
admet-2338	69	38	the	the	DET
admet-2338	69	39	concentration	concentration	NOUN
admet-2338	69	40	of	of	ADP
admet-2338	69	41	nu2	nu2	PROPN
admet-2338	69	42	and	and	CCONJ
admet-2338	69	43	sds	sds	PROPN
admet-2338	69	44	.	.	PUNCT
admet-2338	70	1	a	a	DET
admet-2338	70	2	precise	precise	ADJ
admet-2338	70	3	concentration	concentration	NOUN
admet-2338	70	4	of	of	ADP
admet-2338	70	5	sfn	sfn	PROPN
admet-2338	70	6	was	be	AUX
admet-2338	70	7	dissolved	dissolve	VERB
admet-2338	70	8	in	in	ADP
admet-2338	70	9	0.25	0.25	NUM
admet-2338	70	10	ml	ml	NOUN
admet-2338	70	11	of	of	ADP
admet-2338	70	12	dmso	dmso	NOUN
admet-2338	70	13	in	in	ADP
admet-2338	70	14	a	a	DET
admet-2338	70	15	mortar	mortar	NOUN
admet-2338	70	16	and	and	CCONJ
admet-2338	70	17	pestle	pestle	NOUN
admet-2338	70	18	in	in	ADP
admet-2338	70	19	which	which	PRON
admet-2338	70	20	sds	sds	PROPN
admet-2338	70	21	was	be	AUX
admet-2338	70	22	added	add	VERB
admet-2338	70	23	with	with	ADP
admet-2338	70	24	the	the	DET
admet-2338	70	25	addition	addition	NOUN
admet-2338	70	26	of	of	ADP
admet-2338	70	27	0.5	0.5	NUM
admet-2338	70	28	ml	ml	NOUN
admet-2338	70	29	of	of	ADP
admet-2338	70	30	isopropyl	isopropyl	NOUN
admet-2338	70	31	alcohol	alcohol	PROPN
admet-2338	70	32	(	(	PUNCT
admet-2338	70	33	ipa	ipa	PROPN
admet-2338	70	34	)	)	PUNCT
admet-2338	70	35	,	,	PUNCT
admet-2338	70	36	and	and	CCONJ
admet-2338	70	37	the	the	DET
admet-2338	70	38	mixture	mixture	NOUN
admet-2338	70	39	was	be	AUX
admet-2338	70	40	triturated	triturate	VERB
admet-2338	70	41	for	for	ADP
admet-2338	70	42	10	10	NUM
admet-2338	70	43	mins	min	NOUN
admet-2338	70	44	.	.	PUNCT
admet-2338	71	1	nu2	nu2	PROPN
admet-2338	71	2	was	be	AUX
admet-2338	71	3	added	add	VERB
admet-2338	71	4	gradually	gradually	ADV
admet-2338	71	5	to	to	ADP
admet-2338	71	6	the	the	DET
admet-2338	71	7	above	above	ADJ
admet-2338	71	8	mixture	mixture	NOUN
admet-2338	71	9	with	with	ADP
admet-2338	71	10	vigorous	vigorous	ADJ
admet-2338	71	11	unidirectional	unidirectional	ADJ
admet-2338	71	12	trituration	trituration	NOUN
admet-2338	71	13	for	for	ADP
admet-2338	71	14	another	another	DET
admet-2338	71	15	20	20	NUM
admet-2338	71	16	minutes	minute	NOUN
admet-2338	71	17	.	.	PUNCT
admet-2338	72	1	the	the	DET
admet-2338	72	2	obtained	obtain	VERB
admet-2338	72	3	sfn	sfn	PROPN
admet-2338	72	4	-	-	PUNCT
admet-2338	72	5	ssd	ssd	NOUN
admet-2338	72	6	was	be	AUX
admet-2338	72	7	dried	dry	VERB
admet-2338	72	8	at	at	ADP
admet-2338	72	9	60	60	NUM
admet-2338	72	10	°	°	ADP
admet-2338	72	11	c	c	NOUN
admet-2338	72	12	for	for	ADP
admet-2338	72	13	6	6	NUM
admet-2338	72	14	hours	hour	NOUN
admet-2338	72	15	and	and	CCONJ
admet-2338	72	16	stored	store	VERB
admet-2338	72	17	in	in	ADP
admet-2338	72	18	a	a	DET
admet-2338	72	19	vacuum	vacuum	NOUN
admet-2338	72	20	for	for	ADP
admet-2338	72	21	further	further	ADJ
admet-2338	72	22	analysis	analysis	NOUN
admet-2338	72	23	.	.	PUNCT
admet-2338	73	1	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	PROPN
admet-2338	73	2	b.	b.	PROPN
admet-2338	73	3	kumar	kumar	PROPN
admet-2338	73	4	panda	panda	PROPN
admet-2338	73	5	et	et	PROPN
admet-2338	73	6	al	al	PROPN
admet-2338	73	7	.	.	PROPN
admet-2338	73	8	admet	admet	PROPN
admet-2338	73	9	&	&	CCONJ
admet-2338	73	10	dmpk	dmpk	PROPN
admet-2338	73	11	12(4	12(4	PROPN
admet-2338	73	12	)	)	PUNCT
admet-2338	73	13	(	(	PUNCT
admet-2338	73	14	2024	2024	NUM
admet-2338	73	15	)	)	PUNCT
admet-2338	73	16	687	687	NUM
admet-2338	73	17	-	-	SYM
admet-2338	73	18	702	702	NUM
admet-2338	73	19	690	690	NUM
admet-2338	73	20	table	table	NOUN
admet-2338	73	21	1	1	NUM
admet-2338	73	22	.	.	PUNCT
admet-2338	73	23	independent	independent	ADJ
admet-2338	73	24	variables	variable	NOUN
admet-2338	73	25	and	and	CCONJ
admet-2338	73	26	levels	level	NOUN
admet-2338	73	27	for	for	ADP
admet-2338	73	28	the	the	DET
admet-2338	73	29	optimization	optimization	NOUN
admet-2338	73	30	by	by	ADP
admet-2338	73	31	32	32	NUM
admet-2338	73	32	full	full	ADJ
admet-2338	73	33	factorial	factorial	ADJ
admet-2338	73	34	design	design	NOUN
admet-2338	73	35	independent	independent	ADJ
admet-2338	73	36	variables	variable	NOUN
admet-2338	73	37	levels	level	NOUN
admet-2338	73	38	dependent	dependent	ADJ
admet-2338	73	39	variable	variable	NOUN
admet-2338	73	40	-1	-1	NOUN
admet-2338	73	41	0	0	PUNCT
admet-2338	74	1	+1	+1	ADJ
admet-2338	74	2	solubility	solubility	NOUN
admet-2338	74	3	of	of	ADP
admet-2338	74	4	sfn	sfn	PROPN
admet-2338	74	5	amount	amount	NOUN
admet-2338	74	6	,	,	PUNCT
admet-2338	74	7	mg	mg	PROPN
admet-2338	74	8	concentration	concentration	NOUN
admet-2338	74	9	of	of	ADP
admet-2338	74	10	sds	sds	PROPN
admet-2338	74	11	15	15	NUM
admet-2338	74	12	25	25	NUM
admet-2338	74	13	35	35	NUM
admet-2338	74	14	concentration	concentration	NOUN
admet-2338	74	15	of	of	ADP
admet-2338	74	16	nu2	nu2	PROPN
admet-2338	74	17	100	100	NUM
admet-2338	74	18	150	150	NUM
admet-2338	74	19	200	200	NUM
admet-2338	74	20	characterization	characterization	NOUN
admet-2338	74	21	of	of	ADP
admet-2338	74	22	sfn	sfn	PROPN
admet-2338	74	23	-	-	PUNCT
admet-2338	74	24	ssd	ssd	NOUN
admet-2338	74	25	yield	yield	NOUN
admet-2338	74	26	and	and	CCONJ
admet-2338	74	27	sfn	sfn	PROPN
admet-2338	74	28	content	content	NOUN
admet-2338	74	29	the	the	DET
admet-2338	74	30	dried	dry	VERB
admet-2338	74	31	weight	weight	NOUN
admet-2338	74	32	of	of	ADP
admet-2338	74	33	sfn	sfn	PROPN
admet-2338	74	34	-	-	PUNCT
admet-2338	74	35	ssd	ssd	NOUN
admet-2338	74	36	was	be	AUX
admet-2338	74	37	recorded	record	VERB
admet-2338	74	38	as	as	ADP
admet-2338	74	39	the	the	DET
admet-2338	74	40	practical	practical	ADJ
admet-2338	74	41	yield	yield	NOUN
admet-2338	74	42	.	.	PUNCT
admet-2338	75	1	the	the	DET
admet-2338	75	2	sfn	sfn	PROPN
admet-2338	75	3	-	-	PUNCT
admet-2338	75	4	ssd	ssd	NOUN
admet-2338	75	5	samples	sample	NOUN
admet-2338	75	6	were	be	AUX
admet-2338	75	7	dissolved	dissolve	VERB
admet-2338	75	8	in	in	ADP
admet-2338	75	9	an	an	DET
admet-2338	75	10	appropriate	appropriate	ADJ
admet-2338	75	11	amount	amount	NOUN
admet-2338	75	12	of	of	ADP
admet-2338	75	13	methanol	methanol	NOUN
admet-2338	75	14	using	use	VERB
admet-2338	75	15	a	a	DET
admet-2338	75	16	cyclomixer	cyclomixer	NOUN
admet-2338	75	17	and	and	CCONJ
admet-2338	75	18	an	an	DET
admet-2338	75	19	ultrasonicator	ultrasonicator	NOUN
admet-2338	75	20	.	.	PUNCT
admet-2338	76	1	the	the	DET
admet-2338	76	2	sfn	sfn	PROPN
admet-2338	76	3	content	content	NOUN
admet-2338	76	4	was	be	AUX
admet-2338	76	5	then	then	ADV
admet-2338	76	6	measured	measure	VERB
admet-2338	76	7	at	at	ADP
admet-2338	76	8	265	265	NUM
admet-2338	76	9	nm	nm	NOUN
admet-2338	76	10	with	with	ADP
admet-2338	76	11	a	a	DET
admet-2338	76	12	spectrophotometer	spectrophotometer	NOUN
admet-2338	76	13	(	(	PUNCT
admet-2338	76	14	uv-530	uv-530	PROPN
admet-2338	76	15	;	;	PUNCT
admet-2338	76	16	jasco	jasco	PROPN
admet-2338	76	17	,	,	PUNCT
admet-2338	76	18	japan	japan	PROPN
admet-2338	76	19	)	)	PUNCT
admet-2338	76	20	after	after	ADP
admet-2338	76	21	making	make	VERB
admet-2338	76	22	the	the	DET
admet-2338	76	23	necessary	necessary	ADJ
admet-2338	76	24	dilutions	dilution	NOUN
admet-2338	76	25	[	[	X
admet-2338	76	26	14	14	NUM
admet-2338	76	27	]	]	PUNCT
admet-2338	76	28	.	.	PUNCT
admet-2338	77	1	saturation	saturation	NOUN
admet-2338	77	2	solubility	solubility	NOUN
admet-2338	77	3	the	the	DET
admet-2338	77	4	solubility	solubility	NOUN
admet-2338	77	5	of	of	ADP
admet-2338	77	6	sfn	sfn	PROPN
admet-2338	77	7	from	from	ADP
admet-2338	77	8	sfn	sfn	PROPN
admet-2338	77	9	-	-	PUNCT
admet-2338	77	10	ssd	ssd	NOUN
admet-2338	77	11	was	be	AUX
admet-2338	77	12	analysed	analyse	VERB
admet-2338	77	13	by	by	ADP
admet-2338	77	14	adding	add	VERB
admet-2338	77	15	an	an	DET
admet-2338	77	16	excess	excess	ADJ
admet-2338	77	17	amount	amount	NOUN
admet-2338	77	18	of	of	ADP
admet-2338	77	19	ssd	ssd	NOUN
admet-2338	77	20	in	in	ADP
admet-2338	77	21	2	2	NUM
admet-2338	77	22	ml	ml	NOUN
admet-2338	77	23	of	of	ADP
admet-2338	77	24	double	double	ADJ
admet-2338	77	25	distilled	distil	VERB
admet-2338	77	26	water	water	NOUN
admet-2338	77	27	and	and	CCONJ
admet-2338	77	28	kept	keep	VERB
admet-2338	77	29	on	on	ADP
admet-2338	77	30	a	a	DET
admet-2338	77	31	mechanical	mechanical	ADJ
admet-2338	77	32	shaker	shaker	NOUN
admet-2338	77	33	for	for	ADP
admet-2338	77	34	24	24	NUM
admet-2338	77	35	hours	hour	NOUN
admet-2338	77	36	.	.	PUNCT
admet-2338	78	1	the	the	DET
admet-2338	78	2	dispersion	dispersion	NOUN
admet-2338	78	3	was	be	AUX
admet-2338	78	4	filtered	filter	VERB
admet-2338	78	5	using	use	VERB
admet-2338	78	6	a	a	DET
admet-2338	78	7	0.45	0.45	NUM
admet-2338	78	8	µm	µm	ADP
admet-2338	78	9	syringe	syringe	NOUN
admet-2338	78	10	filter	filter	NOUN
admet-2338	78	11	and	and	CCONJ
admet-2338	78	12	the	the	DET
admet-2338	78	13	concentration	concentration	NOUN
admet-2338	78	14	of	of	ADP
admet-2338	78	15	sfn	sfn	PROPN
admet-2338	78	16	in	in	ADP
admet-2338	78	17	the	the	DET
admet-2338	78	18	filtrate	filtrate	NOUN
admet-2338	78	19	was	be	AUX
admet-2338	78	20	determined	determine	VERB
admet-2338	78	21	after	after	ADP
admet-2338	78	22	suitable	suitable	ADJ
admet-2338	78	23	dilution	dilution	NOUN
admet-2338	78	24	by	by	ADP
admet-2338	78	25	uv	uv	NOUN
admet-2338	78	26	spectrometry	spectrometry	NOUN
admet-2338	78	27	(	(	PUNCT
admet-2338	78	28	uv-530	uv-530	PROPN
admet-2338	78	29	;	;	PUNCT
admet-2338	78	30	jasco	jasco	PROPN
admet-2338	78	31	,	,	PUNCT
admet-2338	78	32	japan	japan	PROPN
admet-2338	78	33	)	)	PUNCT
admet-2338	78	34	at	at	ADP
admet-2338	78	35	λmax	λmax	NOUN
admet-2338	78	36	of	of	ADP
admet-2338	78	37	265	265	NUM
admet-2338	78	38	nm	nm	NOUN
admet-2338	79	1	[	[	X
admet-2338	79	2	15	15	NUM
admet-2338	79	3	]	]	PUNCT
admet-2338	79	4	.	.	PUNCT
admet-2338	80	1	residual	residual	ADJ
admet-2338	80	2	solvent	solvent	ADJ
admet-2338	80	3	content	content	NOUN
admet-2338	80	4	determination	determination	NOUN
admet-2338	80	5	the	the	DET
admet-2338	80	6	practical	practical	ADJ
admet-2338	80	7	yield	yield	NOUN
admet-2338	80	8	was	be	AUX
admet-2338	80	9	determined	determine	VERB
admet-2338	80	10	by	by	ADP
admet-2338	80	11	recording	record	VERB
admet-2338	80	12	the	the	DET
admet-2338	80	13	dried	dry	VERB
admet-2338	80	14	weight	weight	NOUN
admet-2338	80	15	of	of	ADP
admet-2338	80	16	sfn	sfn	PROPN
admet-2338	80	17	-	-	PUNCT
admet-2338	80	18	ssd	ssd	NOUN
admet-2338	80	19	.	.	PUNCT
admet-2338	81	1	the	the	DET
admet-2338	81	2	sfn	sfn	PROPN
admet-2338	81	3	-	-	PUNCT
admet-2338	81	4	ssd	ssd	NOUN
admet-2338	81	5	samples	sample	NOUN
admet-2338	81	6	were	be	AUX
admet-2338	81	7	dissolved	dissolve	VERB
admet-2338	81	8	in	in	ADP
admet-2338	81	9	a	a	DET
admet-2338	81	10	suitable	suitable	ADJ
admet-2338	81	11	amount	amount	NOUN
admet-2338	81	12	of	of	ADP
admet-2338	81	13	methanol	methanol	NOUN
admet-2338	81	14	using	use	VERB
admet-2338	81	15	a	a	DET
admet-2338	81	16	cyclomixer	cyclomixer	NOUN
admet-2338	81	17	and	and	CCONJ
admet-2338	81	18	an	an	DET
admet-2338	81	19	ultrasonicator	ultrasonicator	NOUN
admet-2338	81	20	.	.	PUNCT
admet-2338	82	1	after	after	ADP
admet-2338	82	2	appropriate	appropriate	ADJ
admet-2338	82	3	dilutions	dilution	NOUN
admet-2338	82	4	,	,	PUNCT
admet-2338	82	5	the	the	DET
admet-2338	82	6	sfn	sfn	PROPN
admet-2338	82	7	content	content	NOUN
admet-2338	82	8	was	be	AUX
admet-2338	82	9	measured	measure	VERB
admet-2338	82	10	at	at	ADP
admet-2338	82	11	265	265	NUM
admet-2338	82	12	nm	nm	NOUN
admet-2338	82	13	using	use	VERB
admet-2338	82	14	a	a	DET
admet-2338	82	15	spectrophotometer	spectrophotometer	NOUN
admet-2338	82	16	(	(	PUNCT
admet-2338	82	17	uv-530	uv-530	PROPN
admet-2338	82	18	;	;	PUNCT
admet-2338	82	19	jasco	jasco	PROPN
admet-2338	82	20	,	,	PUNCT
admet-2338	82	21	japan	japan	PROPN
admet-2338	82	22	)	)	PUNCT
admet-2338	82	23	.	.	PUNCT
admet-2338	83	1	fourier	fourier	PROPN
admet-2338	83	2	transform	transform	VERB
admet-2338	83	3	-	-	PUNCT
admet-2338	83	4	infrared	infrare	VERB
admet-2338	83	5	spectroscopy	spectroscopy	VERB
admet-2338	83	6	the	the	DET
admet-2338	83	7	fourier	fourier	NOUN
admet-2338	83	8	transform	transform	NOUN
admet-2338	83	9	-	-	PUNCT
admet-2338	83	10	infrared	infrared	ADJ
admet-2338	83	11	(	(	PUNCT
admet-2338	83	12	ftir	ftir	PROPN
admet-2338	83	13	)	)	PUNCT
admet-2338	83	14	spectra	spectra	NOUN
admet-2338	83	15	of	of	ADP
admet-2338	83	16	pure	pure	ADJ
admet-2338	83	17	sfn	sfn	PROPN
admet-2338	83	18	,	,	PUNCT
admet-2338	83	19	nu2	nu2	INTJ
admet-2338	83	20	,	,	PUNCT
admet-2338	83	21	physical	physical	ADJ
admet-2338	83	22	mixture	mixture	NOUN
admet-2338	83	23	and	and	CCONJ
admet-2338	83	24	optimized	optimize	VERB
admet-2338	83	25	sfn	sfn	PROPN
admet-2338	83	26	-	-	PUNCT
admet-2338	83	27	ssd	ssd	NOUN
admet-2338	83	28	were	be	AUX
admet-2338	83	29	recorded	record	VERB
admet-2338	83	30	using	use	VERB
admet-2338	83	31	the	the	DET
admet-2338	83	32	jasco	jasco	PROPN
admet-2338	83	33	v4100	v4100	PROPN
admet-2338	83	34	ftir	ftir	PROPN
admet-2338	83	35	(	(	PUNCT
admet-2338	83	36	tokyo	tokyo	PROPN
admet-2338	83	37	,	,	PUNCT
admet-2338	83	38	japan	japan	PROPN
admet-2338	83	39	)	)	PUNCT
admet-2338	83	40	.	.	PUNCT
admet-2338	84	1	in	in	ADP
admet-2338	84	2	transmission	transmission	NOUN
admet-2338	84	3	mode	mode	NOUN
admet-2338	84	4	,	,	PUNCT
admet-2338	84	5	the	the	DET
admet-2338	84	6	samples	sample	NOUN
admet-2338	84	7	were	be	AUX
admet-2338	84	8	triturated	triturate	VERB
admet-2338	84	9	with	with	ADP
admet-2338	84	10	ir	ir	NOUN
admet-2338	84	11	-	-	PUNCT
admet-2338	84	12	grade	grade	NOUN
admet-2338	84	13	kbr	kbr	PROPN
admet-2338	84	14	and	and	CCONJ
admet-2338	84	15	scanned	scan	VERB
admet-2338	84	16	throughout	throughout	ADP
admet-2338	84	17	a	a	DET
admet-2338	84	18	4000	4000	NUM
admet-2338	84	19	to	to	PART
admet-2338	84	20	400	400	NUM
admet-2338	84	21	cm-1	cm-1	NOUN
admet-2338	84	22	wavenumber	wavenumber	NOUN
admet-2338	84	23	range	range	NOUN
admet-2338	84	24	.	.	PUNCT
admet-2338	85	1	all	all	DET
admet-2338	85	2	samples	sample	NOUN
admet-2338	85	3	distinguishing	distinguish	VERB
admet-2338	85	4	peaks	peak	NOUN
admet-2338	85	5	were	be	AUX
admet-2338	85	6	carefully	carefully	ADV
admet-2338	85	7	examined	examine	VERB
admet-2338	85	8	to	to	PART
admet-2338	85	9	identify	identify	VERB
admet-2338	85	10	potential	potential	ADJ
admet-2338	85	11	interactions	interaction	NOUN
admet-2338	85	12	[	[	X
admet-2338	85	13	16	16	NUM
admet-2338	85	14	]	]	PUNCT
admet-2338	85	15	.	.	PUNCT
admet-2338	86	1	x	x	X
admet-2338	86	2	-	-	PUNCT
admet-2338	86	3	ray	ray	NOUN
admet-2338	86	4	powder	powder	NOUN
admet-2338	86	5	diffraction	diffraction	NOUN
admet-2338	86	6	the	the	DET
admet-2338	86	7	x	x	NOUN
admet-2338	86	8	-	-	NOUN
admet-2338	86	9	ray	ray	NOUN
admet-2338	86	10	powder	powder	NOUN
admet-2338	86	11	diffraction	diffraction	NOUN
admet-2338	86	12	of	of	ADP
admet-2338	86	13	pure	pure	ADJ
admet-2338	86	14	sfn	sfn	PROPN
admet-2338	86	15	,	,	PUNCT
admet-2338	86	16	nu2	nu2	INTJ
admet-2338	86	17	,	,	PUNCT
admet-2338	86	18	physical	physical	ADJ
admet-2338	86	19	mixture	mixture	NOUN
admet-2338	86	20	and	and	CCONJ
admet-2338	86	21	optimized	optimize	VERB
admet-2338	86	22	sfn	sfn	PROPN
admet-2338	86	23	-	-	PUNCT
admet-2338	86	24	ssd	ssd	NOUN
admet-2338	86	25	were	be	AUX
admet-2338	86	26	assessed	assess	VERB
admet-2338	86	27	by	by	ADP
admet-2338	86	28	powder	powder	NOUN
admet-2338	86	29	x	x	NOUN
admet-2338	86	30	-	-	NOUN
admet-2338	86	31	ray	ray	NOUN
admet-2338	86	32	diffractogram	diffractogram	PROPN
admet-2338	86	33	(	(	PUNCT
admet-2338	86	34	pxrd	pxrd	PROPN
admet-2338	86	35	)	)	PUNCT
admet-2338	86	36	(	(	PUNCT
admet-2338	86	37	pw	pw	PROPN
admet-2338	86	38	1729	1729	NUM
admet-2338	86	39	,	,	PUNCT
admet-2338	86	40	philips	philip	NOUN
admet-2338	86	41	,	,	PUNCT
admet-2338	86	42	netherlands	netherlands	PROPN
admet-2338	86	43	)	)	PUNCT
admet-2338	86	44	using	use	VERB
admet-2338	86	45	cu	cu	PROPN
admet-2338	86	46	as	as	ADP
admet-2338	86	47	the	the	DET
admet-2338	86	48	anode	anode	NOUN
admet-2338	86	49	material	material	NOUN
admet-2338	86	50	and	and	CCONJ
admet-2338	86	51	a	a	DET
admet-2338	86	52	crystal	crystal	NOUN
admet-2338	86	53	graphite	graphite	NOUN
admet-2338	86	54	monochromator	monochromator	NOUN
admet-2338	86	55	running	run	VERB
admet-2338	86	56	at	at	ADP
admet-2338	86	57	30	30	NUM
admet-2338	86	58	kv	kv	NOUN
admet-2338	86	59	and	and	CCONJ
admet-2338	86	60	30	30	NUM
admet-2338	86	61	ma	ma	PROPN
admet-2338	86	62	.	.	PUNCT
admet-2338	87	1	the	the	DET
admet-2338	87	2	diffractograms	diffractogram	NOUN
admet-2338	87	3	were	be	AUX
admet-2338	87	4	produced	produce	VERB
admet-2338	87	5	using	use	VERB
admet-2338	87	6	a	a	DET
admet-2338	87	7	0.02626	0.02626	NUM
admet-2338	87	8	°	°	PRON
admet-2338	87	9	step	step	NOUN
admet-2338	87	10	size	size	NOUN
admet-2338	87	11	and	and	CCONJ
admet-2338	87	12	a	a	DET
admet-2338	87	13	2	2	NUM
admet-2338	87	14	(	(	PUNCT
admet-2338	87	15	diffraction	diffraction	NOUN
admet-2338	87	16	angle	angle	NOUN
admet-2338	87	17	)	)	PUNCT
admet-2338	87	18	angular	angular	ADJ
admet-2338	87	19	range	range	NOUN
admet-2338	87	20	of	of	ADP
admet-2338	87	21	5	5	NUM
admet-2338	87	22	to	to	PART
admet-2338	87	23	60	60	NUM
admet-2338	87	24	°	°	NOUN
admet-2338	88	1	[	[	X
admet-2338	88	2	18	18	NUM
admet-2338	88	3	]	]	PUNCT
admet-2338	88	4	.	.	PUNCT
admet-2338	89	1	scanning	scan	VERB
admet-2338	89	2	electronic	electronic	ADJ
admet-2338	89	3	microscopy	microscopy	NOUN
admet-2338	89	4	scanning	scan	VERB
admet-2338	89	5	electronic	electronic	ADJ
admet-2338	89	6	microscopy	microscopy	NOUN
admet-2338	89	7	(	(	PUNCT
admet-2338	89	8	sem)was	sem)was	ADV
admet-2338	89	9	used	use	VERB
admet-2338	89	10	to	to	PART
admet-2338	89	11	examine	examine	VERB
admet-2338	89	12	the	the	DET
admet-2338	89	13	surface	surface	NOUN
admet-2338	89	14	morphology	morphology	NOUN
admet-2338	89	15	of	of	ADP
admet-2338	89	16	sfn	sfn	PROPN
admet-2338	89	17	and	and	CCONJ
admet-2338	89	18	sfn	sfn	PROPN
admet-2338	89	19	-	-	PUNCT
admet-2338	89	20	ssd	ssd	PROPN
admet-2338	89	21	(	(	PUNCT
admet-2338	89	22	joel	joel	PROPN
admet-2338	89	23	,	,	PUNCT
admet-2338	89	24	japan	japan	PROPN
admet-2338	89	25	)	)	PUNCT
admet-2338	89	26	.	.	PUNCT
admet-2338	90	1	the	the	DET
admet-2338	90	2	samples	sample	NOUN
admet-2338	90	3	were	be	AUX
admet-2338	90	4	applied	apply	VERB
admet-2338	90	5	with	with	ADP
admet-2338	90	6	a	a	DET
admet-2338	90	7	thin	thin	ADJ
admet-2338	90	8	coat	coat	NOUN
admet-2338	90	9	of	of	ADP
admet-2338	90	10	gold	gold	NOUN
admet-2338	90	11	(	(	PUNCT
admet-2338	90	12	about	about	ADV
admet-2338	90	13	24	24	NUM
admet-2338	90	14	nm	nm	NOUN
admet-2338	90	15	)	)	PUNCT
admet-2338	90	16	in	in	ADP
admet-2338	90	17	a	a	DET
admet-2338	90	18	vacuum	vacuum	NOUN
admet-2338	90	19	to	to	PART
admet-2338	90	20	make	make	VERB
admet-2338	90	21	the	the	DET
admet-2338	90	22	samples	sample	NOUN
admet-2338	90	23	electrically	electrically	ADV
admet-2338	90	24	conductive	conductive	ADJ
admet-2338	90	25	[	[	X
admet-2338	90	26	16	16	NUM
admet-2338	90	27	]	]	PUNCT
admet-2338	90	28	.	.	PUNCT
admet-2338	91	1	differential	differential	PROPN
admet-2338	91	2	scanning	scan	VERB
admet-2338	91	3	calorimetry	calorimetry	NOUN
admet-2338	91	4	a	a	DET
admet-2338	91	5	differential	differential	NOUN
admet-2338	91	6	scanning	scan	VERB
admet-2338	91	7	calorimeter	calorimeter	NOUN
admet-2338	91	8	(	(	PUNCT
admet-2338	91	9	dsc	dsc	NOUN
admet-2338	91	10	)	)	PUNCT
admet-2338	91	11	(	(	PUNCT
admet-2338	91	12	mettler	mettler	PROPN
admet-2338	91	13	toledo	toledo	PROPN
admet-2338	91	14	dsc	dsc	PROPN
admet-2338	91	15	821	821	NUM
admet-2338	91	16	,	,	PUNCT
admet-2338	91	17	switzerland	switzerland	PROPN
admet-2338	91	18	)	)	PUNCT
admet-2338	91	19	was	be	AUX
admet-2338	91	20	used	use	VERB
admet-2338	91	21	to	to	PART
admet-2338	91	22	measure	measure	VERB
admet-2338	91	23	the	the	DET
admet-2338	91	24	thermal	thermal	ADJ
admet-2338	91	25	behaviour	behaviour	NOUN
admet-2338	91	26	of	of	ADP
admet-2338	91	27	the	the	DET
admet-2338	91	28	pure	pure	ADJ
admet-2338	91	29	sfn	sfn	PROPN
admet-2338	91	30	,	,	PUNCT
admet-2338	91	31	nu2	nu2	INTJ
admet-2338	91	32	,	,	PUNCT
admet-2338	91	33	physical	physical	ADJ
admet-2338	91	34	mixture	mixture	NOUN
admet-2338	91	35	and	and	CCONJ
admet-2338	91	36	sfn	sfn	PROPN
admet-2338	91	37	-	-	PUNCT
admet-2338	91	38	ssd	ssd	NOUN
admet-2338	91	39	.	.	PUNCT
admet-2338	92	1	the	the	DET
admet-2338	92	2	samples	sample	NOUN
admet-2338	92	3	(	(	PUNCT
admet-2338	92	4	3	3	NUM
admet-2338	92	5	-	-	SYM
admet-2338	92	6	5	5	NUM
admet-2338	92	7	mg	mg	NOUN
admet-2338	92	8	)	)	PUNCT
admet-2338	92	9	were	be	AUX
admet-2338	92	10	enclosed	enclose	VERB
admet-2338	92	11	in	in	ADP
admet-2338	92	12	an	an	DET
admet-2338	92	13	aluminium	aluminium	NOUN
admet-2338	92	14	pan	pan	NOUN
admet-2338	92	15	and	and	CCONJ
admet-2338	92	16	heated	heated	ADJ
admet-2338	92	17	at	at	ADP
admet-2338	92	18	a	a	DET
admet-2338	92	19	rate	rate	NOUN
admet-2338	92	20	of	of	ADP
admet-2338	92	21	10	10	NUM
admet-2338	92	22	°	°	NOUN
admet-2338	92	23	c	c	NOUN
admet-2338	92	24	/	/	SYM
admet-2338	92	25	min	min	NOUN
admet-2338	92	26	while	while	SCONJ
admet-2338	92	27	being	be	AUX
admet-2338	92	28	purged	purge	VERB
admet-2338	92	29	with	with	ADP
admet-2338	92	30	nitrogen	nitrogen	NOUN
admet-2338	92	31	at	at	ADP
admet-2338	92	32	a	a	DET
admet-2338	92	33	flow	flow	NOUN
admet-2338	92	34	rate	rate	NOUN
admet-2338	92	35	of	of	ADP
admet-2338	92	36	50	50	NUM
admet-2338	92	37	ml	ml	NOUN
admet-2338	92	38	/	/	SYM
admet-2338	92	39	min	min	NOUN
admet-2338	92	40	.	.	PUNCT
admet-2338	93	1	the	the	DET
admet-2338	93	2	temperature	temperature	NOUN
admet-2338	93	3	range	range	NOUN
admet-2338	93	4	covered	cover	VERB
admet-2338	93	5	was	be	AUX
admet-2338	93	6	40	40	NUM
admet-2338	93	7	to	to	PART
admet-2338	93	8	320	320	NUM
admet-2338	93	9	°	°	NOUN
admet-2338	93	10	c	c	NOUN
admet-2338	93	11	.	.	PUNCT
admet-2338	94	1	the	the	DET
admet-2338	94	2	temperature	temperature	NOUN
admet-2338	94	3	and	and	CCONJ
admet-2338	94	4	enthalpy	enthalpy	NOUN
admet-2338	94	5	were	be	AUX
admet-2338	94	6	calibrated	calibrate	VERB
admet-2338	94	7	using	use	VERB
admet-2338	94	8	the	the	DET
admet-2338	94	9	industry	industry	NOUN
admet-2338	94	10	-	-	PUNCT
admet-2338	94	11	standard	standard	ADJ
admet-2338	94	12	aluminium	aluminium	NOUN
admet-2338	94	13	pan	pan	NOUN
admet-2338	94	14	[	[	X
admet-2338	94	15	18	18	NUM
admet-2338	94	16	]	]	PUNCT
admet-2338	94	17	.	.	PUNCT
admet-2338	95	1	admet	admet	PROPN
admet-2338	95	2	&	&	CCONJ
admet-2338	95	3	dmpk	dmpk	PROPN
admet-2338	95	4	12(4	12(4	PROPN
admet-2338	95	5	)	)	PUNCT
admet-2338	95	6	(	(	PUNCT
admet-2338	95	7	2024	2024	NUM
admet-2338	95	8	)	)	PUNCT
admet-2338	95	9	687	687	NUM
admet-2338	95	10	-	-	SYM
admet-2338	95	11	702	702	NUM
admet-2338	95	12	neusilin	neusilin	PROPN
admet-2338	95	13	us2	us2	PROPN
admet-2338	95	14	based	base	VERB
admet-2338	95	15	surface	surface	NOUN
admet-2338	95	16	solid	solid	ADJ
admet-2338	95	17	dispersion	dispersion	NOUN
admet-2338	95	18	of	of	ADP
admet-2338	95	19	sorafenib	sorafenib	NOUN
admet-2338	95	20	tosylate	tosylate	VERB
admet-2338	95	21	doi	doi	NOUN
admet-2338	95	22	:	:	PUNCT
admet-2338	95	23	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	NOUN
admet-2338	95	24	691	691	NUM
admet-2338	95	25	preparation	preparation	NOUN
admet-2338	95	26	of	of	ADP
admet-2338	95	27	sfn	sfn	PROPN
admet-2338	95	28	-	-	PUNCT
admet-2338	95	29	ssd	ssd	PROPN
admet-2338	95	30	and	and	CCONJ
admet-2338	95	31	sfn	sfn	ADJ
admet-2338	95	32	immediate	immediate	ADJ
admet-2338	95	33	-	-	PUNCT
admet-2338	95	34	release	release	NOUN
admet-2338	95	35	tablet	tablet	NOUN
admet-2338	95	36	the	the	DET
admet-2338	95	37	sfn	sfn	PROPN
admet-2338	95	38	-	-	PUNCT
admet-2338	95	39	ssd	ssd	NOUN
admet-2338	95	40	and	and	CCONJ
admet-2338	95	41	pure	pure	ADJ
admet-2338	95	42	sfn	sfn	PROPN
admet-2338	95	43	equivalent	equivalent	ADJ
admet-2338	95	44	to	to	ADP
admet-2338	95	45	100	100	NUM
admet-2338	95	46	mg	mg	PROPN
admet-2338	95	47	sfn	sfn	NUM
admet-2338	95	48	immediate	immediate	ADJ
admet-2338	95	49	-	-	PUNCT
admet-2338	95	50	release	release	NOUN
admet-2338	95	51	tablets	tablet	NOUN
admet-2338	95	52	were	be	AUX
admet-2338	95	53	prepared	prepare	VERB
admet-2338	95	54	by	by	ADP
admet-2338	95	55	wet	wet	ADJ
admet-2338	95	56	granulation	granulation	NOUN
admet-2338	95	57	.	.	PUNCT
admet-2338	96	1	all	all	DET
admet-2338	96	2	ingredients	ingredient	NOUN
admet-2338	96	3	were	be	AUX
admet-2338	96	4	accurately	accurately	ADV
admet-2338	96	5	weighed	weigh	VERB
admet-2338	96	6	according	accord	VERB
admet-2338	96	7	to	to	ADP
admet-2338	96	8	the	the	DET
admet-2338	96	9	formula	formula	NOUN
admet-2338	96	10	given	give	VERB
admet-2338	96	11	in	in	ADP
admet-2338	96	12	table	table	NOUN
admet-2338	96	13	2	2	NUM
admet-2338	96	14	.	.	PUNCT
admet-2338	97	1	the	the	DET
admet-2338	97	2	sfn	sfn	PROPN
admet-2338	97	3	-	-	PUNCT
admet-2338	97	4	ssd	ssd	PROPN
admet-2338	97	5	,	,	PUNCT
admet-2338	97	6	croscarmellose	croscarmellose	ADJ
admet-2338	97	7	and	and	CCONJ
admet-2338	97	8	microcrystalline	microcrystalline	NOUN
admet-2338	97	9	cellulose	cellulose	NOUN
admet-2338	97	10	were	be	AUX
admet-2338	97	11	sieved	sieve	VERB
admet-2338	97	12	through	through	ADP
admet-2338	97	13	sieve	sieve	NOUN
admet-2338	97	14	no	no	DET
admet-2338	97	15	40	40	NUM
admet-2338	97	16	and	and	CCONJ
admet-2338	97	17	transferred	transfer	VERB
admet-2338	97	18	into	into	ADP
admet-2338	97	19	a	a	DET
admet-2338	97	20	mortar	mortar	NOUN
admet-2338	97	21	.	.	PUNCT
admet-2338	98	1	the	the	DET
admet-2338	98	2	pvp	pvp	PROPN
admet-2338	98	3	k30	k30	NOUN
admet-2338	98	4	solution	solution	NOUN
admet-2338	98	5	in	in	ADP
admet-2338	98	6	the	the	DET
admet-2338	98	7	required	require	VERB
admet-2338	98	8	quantity	quantity	NOUN
admet-2338	98	9	of	of	ADP
admet-2338	98	10	isopropyl	isopropyl	NOUN
admet-2338	98	11	alcohol	alcohol	NOUN
admet-2338	98	12	was	be	AUX
admet-2338	98	13	added	add	VERB
admet-2338	98	14	into	into	ADP
admet-2338	98	15	the	the	DET
admet-2338	98	16	mortar	mortar	NOUN
admet-2338	98	17	to	to	ADP
admet-2338	98	18	coherent	coherent	ADJ
admet-2338	98	19	mass	mass	NOUN
admet-2338	98	20	and	and	CCONJ
admet-2338	98	21	passed	pass	VERB
admet-2338	98	22	through	through	ADP
admet-2338	98	23	sieve	sieve	NOUN
admet-2338	98	24	no	no	DET
admet-2338	98	25	12	12	NUM
admet-2338	98	26	to	to	PART
admet-2338	98	27	get	get	VERB
admet-2338	98	28	granules	granule	NOUN
admet-2338	98	29	.	.	PUNCT
admet-2338	99	1	it	it	PRON
admet-2338	99	2	was	be	AUX
admet-2338	99	3	then	then	ADV
admet-2338	99	4	kept	keep	VERB
admet-2338	99	5	in	in	ADP
admet-2338	99	6	an	an	DET
admet-2338	99	7	oven	oven	NOUN
admet-2338	99	8	at	at	ADP
admet-2338	99	9	120	120	NUM
admet-2338	99	10	°	°	NOUN
admet-2338	99	11	c	c	NOUN
admet-2338	99	12	for	for	ADP
admet-2338	99	13	1	1	NUM
admet-2338	99	14	hour	hour	NOUN
admet-2338	99	15	.	.	PUNCT
admet-2338	100	1	the	the	DET
admet-2338	100	2	dried	dry	VERB
admet-2338	100	3	granules	granule	NOUN
admet-2338	100	4	were	be	AUX
admet-2338	100	5	passed	pass	VERB
admet-2338	100	6	through	through	ADP
admet-2338	100	7	sieve	sieve	NOUN
admet-2338	100	8	no	no	NOUN
admet-2338	100	9	.	.	PROPN
admet-2338	100	10	80	80	NUM
admet-2338	100	11	.	.	PUNCT
admet-2338	101	1	the	the	DET
admet-2338	101	2	talc	talc	NOUN
admet-2338	101	3	and	and	CCONJ
admet-2338	101	4	magnesium	magnesium	NOUN
admet-2338	101	5	stearate	stearate	NOUN
admet-2338	101	6	were	be	AUX
admet-2338	101	7	added	add	VERB
admet-2338	101	8	to	to	ADP
admet-2338	101	9	the	the	DET
admet-2338	101	10	granules	granule	NOUN
admet-2338	101	11	and	and	CCONJ
admet-2338	101	12	mixed	mixed	ADJ
admet-2338	101	13	well	well	ADV
admet-2338	101	14	without	without	ADP
admet-2338	101	15	breaking	break	VERB
admet-2338	101	16	the	the	DET
admet-2338	101	17	granules	granule	NOUN
admet-2338	101	18	.	.	PUNCT
admet-2338	102	1	the	the	DET
admet-2338	102	2	granules	granule	NOUN
admet-2338	102	3	were	be	AUX
admet-2338	102	4	evaluated	evaluate	VERB
admet-2338	102	5	for	for	ADP
admet-2338	102	6	various	various	ADJ
admet-2338	102	7	flow	flow	NOUN
admet-2338	102	8	properties	property	NOUN
admet-2338	102	9	such	such	ADJ
admet-2338	102	10	as	as	ADP
admet-2338	102	11	bulk	bulk	ADJ
admet-2338	102	12	density	density	NOUN
admet-2338	102	13	,	,	PUNCT
admet-2338	102	14	tapped	tap	VERB
admet-2338	102	15	density	density	NOUN
admet-2338	102	16	,	,	PUNCT
admet-2338	102	17	carr	carr	PROPN
admet-2338	102	18	’s	’s	PART
admet-2338	102	19	compressibility	compressibility	PROPN
admet-2338	102	20	index	index	PROPN
admet-2338	102	21	,	,	PUNCT
admet-2338	102	22	hausner	hausner	NOUN
admet-2338	102	23	’s	’s	PART
admet-2338	102	24	ratio	ratio	NOUN
admet-2338	102	25	and	and	CCONJ
admet-2338	102	26	angle	angle	NOUN
admet-2338	102	27	of	of	ADP
admet-2338	102	28	repose	repose	NOUN
admet-2338	102	29	.	.	PUNCT
admet-2338	103	1	the	the	DET
admet-2338	103	2	tablets	tablet	NOUN
admet-2338	103	3	were	be	AUX
admet-2338	103	4	punched	punch	VERB
admet-2338	103	5	with	with	ADP
admet-2338	103	6	a	a	DET
admet-2338	103	7	12	12	NUM
admet-2338	103	8	mm	mm	NOUN
admet-2338	103	9	punch	punch	NOUN
admet-2338	103	10	by	by	ADP
admet-2338	103	11	the	the	DET
admet-2338	103	12	rimek	rimek	PROPN
admet-2338	103	13	mini	mini	PROPN
admet-2338	103	14	press	press	NOUN
admet-2338	103	15	(	(	PUNCT
admet-2338	103	16	karnavati	karnavati	PROPN
admet-2338	103	17	engineering	engineering	PROPN
admet-2338	103	18	ltd	ltd	PROPN
admet-2338	103	19	)	)	PUNCT
admet-2338	103	20	.	.	PUNCT
admet-2338	104	1	table	table	NOUN
admet-2338	104	2	2	2	NUM
admet-2338	104	3	.	.	PUNCT
admet-2338	104	4	composition	composition	NOUN
admet-2338	104	5	of	of	ADP
admet-2338	104	6	sfn	sfn	PROPN
admet-2338	104	7	-	-	PUNCT
admet-2338	104	8	ssd	ssd	PROPN
admet-2338	104	9	and	and	CCONJ
admet-2338	104	10	sfn	sfn	ADJ
admet-2338	104	11	immediate	immediate	ADJ
admet-2338	104	12	release	release	NOUN
admet-2338	104	13	tablet	tablet	NOUN
admet-2338	104	14	batches	batch	NOUN
admet-2338	104	15	amount	amount	NOUN
admet-2338	104	16	,	,	PUNCT
admet-2338	104	17	mg	mg	PROPN
admet-2338	104	18	solubility	solubility	PROPN
admet-2338	104	19	*	*	NOUN
admet-2338	104	20	,	,	PUNCT
admet-2338	104	21	mg	mg	PROPN
admet-2338	104	22	/	/	SYM
admet-2338	104	23	ml	ml	NOUN
admet-2338	104	24	sds	sds	PROPN
admet-2338	104	25	nu2	nu2	PROPN
admet-2338	104	26	1	1	NUM
admet-2338	104	27	15	15	NUM
admet-2338	104	28	100	100	NUM
admet-2338	104	29	0.424	0.424	NUM
admet-2338	104	30	±	±	NUM
admet-2338	104	31	0.019	0.019	NUM
admet-2338	104	32	2	2	NUM
admet-2338	104	33	25	25	NUM
admet-2338	104	34	100	100	NUM
admet-2338	104	35	0.513	0.513	NUM
admet-2338	104	36	±	±	NUM
admet-2338	104	37	0.022	0.022	NUM
admet-2338	104	38	3	3	NUM
admet-2338	104	39	35	35	NUM
admet-2338	104	40	100	100	NUM
admet-2338	104	41	0.531	0.531	NUM
admet-2338	104	42	±	±	NUM
admet-2338	104	43	0.032	0.032	NUM
admet-2338	104	44	4	4	NUM
admet-2338	104	45	15	15	NUM
admet-2338	104	46	150	150	NUM
admet-2338	104	47	0.513	0.513	NUM
admet-2338	104	48	±	±	NUM
admet-2338	104	49	0.029	0.029	NUM
admet-2338	104	50	5	5	NUM
admet-2338	104	51	25	25	NUM
admet-2338	104	52	150	150	NUM
admet-2338	104	53	0.703	0.703	NUM
admet-2338	104	54	±	±	NUM
admet-2338	104	55	0.024	0.024	NUM
admet-2338	104	56	6	6	NUM
admet-2338	104	57	35	35	NUM
admet-2338	104	58	150	150	NUM
admet-2338	104	59	0.711	0.711	NUM
admet-2338	104	60	±	±	NUM
admet-2338	104	61	0.024	0.024	NUM
admet-2338	104	62	7	7	NUM
admet-2338	104	63	15	15	NUM
admet-2338	104	64	200	200	NUM
admet-2338	104	65	0.561	0.561	NUM
admet-2338	104	66	±	±	NUM
admet-2338	105	1	0.032	0.032	NUM
admet-2338	105	2	8	8	NUM
admet-2338	105	3	25	25	NUM
admet-2338	105	4	200	200	NUM
admet-2338	105	5	0.713	0.713	NUM
admet-2338	105	6	±	±	NUM
admet-2338	105	7	0.054	0.054	NUM
admet-2338	105	8	9	9	NUM
admet-2338	105	9	35	35	NUM
admet-2338	105	10	200	200	NUM
admet-2338	105	11	0.719	0.719	NUM
admet-2338	105	12	±	±	NUM
admet-2338	105	13	0.038	0.038	NUM
admet-2338	105	14	*	*	PUNCT
admet-2338	105	15	all	all	DET
admet-2338	105	16	the	the	DET
admet-2338	105	17	determinations	determination	NOUN
admet-2338	105	18	were	be	AUX
admet-2338	105	19	performed	perform	VERB
admet-2338	105	20	in	in	ADP
admet-2338	105	21	triplicate	triplicate	NOUN
admet-2338	105	22	and	and	CCONJ
admet-2338	105	23	values	value	NOUN
admet-2338	105	24	are	be	AUX
admet-2338	105	25	expressed	express	VERB
admet-2338	105	26	as	as	ADP
admet-2338	105	27	mean	mean	NOUN
admet-2338	105	28	±	±	NUM
admet-2338	105	29	sd	sd	NOUN
admet-2338	105	30	(	(	PUNCT
admet-2338	105	31	n	n	NOUN
admet-2338	105	32	=	=	SYM
admet-2338	105	33	3	3	NUM
admet-2338	105	34	)	)	PUNCT
admet-2338	105	35	evaluation	evaluation	NOUN
admet-2338	105	36	of	of	ADP
admet-2338	105	37	sfn	sfn	PROPN
admet-2338	105	38	-	-	PUNCT
admet-2338	105	39	ssd	ssd	PROPN
admet-2338	105	40	and	and	CCONJ
admet-2338	105	41	sfn	sfn	ADJ
admet-2338	105	42	immediate	immediate	ADJ
admet-2338	105	43	-	-	PUNCT
admet-2338	105	44	release	release	NOUN
admet-2338	105	45	tablet	tablet	NOUN
admet-2338	105	46	the	the	DET
admet-2338	105	47	tablet	tablet	NOUN
admet-2338	105	48	hardness	hardness	NOUN
admet-2338	105	49	was	be	AUX
admet-2338	105	50	analysed	analyse	VERB
admet-2338	105	51	by	by	ADP
admet-2338	105	52	incrop	incrop	PROPN
admet-2338	105	53	-	-	PUNCT
admet-2338	105	54	ptb	ptb	PROPN
admet-2338	105	55	311e	311e	PROPN
admet-2338	105	56	hardness	hardness	NOUN
admet-2338	105	57	tester	tester	NOUN
admet-2338	105	58	.	.	PUNCT
admet-2338	106	1	randomly	randomly	ADV
admet-2338	106	2	,	,	PUNCT
admet-2338	106	3	three	three	NUM
admet-2338	106	4	tablets	tablet	NOUN
admet-2338	106	5	were	be	AUX
admet-2338	106	6	evaluated	evaluate	VERB
admet-2338	106	7	for	for	ADP
admet-2338	106	8	hardness	hardness	ADJ
admet-2338	106	9	analysis	analysis	NOUN
admet-2338	106	10	and	and	CCONJ
admet-2338	106	11	recorded	record	VERB
admet-2338	106	12	(	(	PUNCT
admet-2338	106	13	kg	kg	NOUN
admet-2338	106	14	/	/	SYM
admet-2338	106	15	cm2	cm2	NOUN
admet-2338	106	16	)	)	PUNCT
admet-2338	106	17	.	.	PUNCT
admet-2338	107	1	the	the	DET
admet-2338	107	2	thickness	thickness	NOUN
admet-2338	107	3	and	and	CCONJ
admet-2338	107	4	diameter	diameter	NOUN
admet-2338	107	5	of	of	ADP
admet-2338	107	6	the	the	DET
admet-2338	107	7	tablet	tablet	NOUN
admet-2338	107	8	were	be	AUX
admet-2338	107	9	measured	measure	VERB
admet-2338	107	10	by	by	ADP
admet-2338	107	11	vernier	vernier	PROPN
admet-2338	107	12	calliper	calliper	NOUN
admet-2338	107	13	(	(	PUNCT
admet-2338	107	14	mitutoyo	mitutoyo	PROPN
admet-2338	107	15	,	,	PUNCT
admet-2338	107	16	usa	usa	PROPN
admet-2338	107	17	)	)	PUNCT
admet-2338	107	18	.	.	PUNCT
admet-2338	108	1	all	all	DET
admet-2338	108	2	measurements	measurement	NOUN
admet-2338	108	3	were	be	AUX
admet-2338	108	4	done	do	VERB
admet-2338	108	5	in	in	ADP
admet-2338	108	6	triplicates	triplicate	NOUN
admet-2338	108	7	(	(	PUNCT
admet-2338	108	8	n=3	n=3	NOUN
admet-2338	108	9	)	)	PUNCT
admet-2338	108	10	.	.	PUNCT
admet-2338	109	1	mean	mean	VERB
admet-2338	109	2	thickness	thickness	NOUN
admet-2338	109	3	and	and	CCONJ
admet-2338	109	4	diameter	diameter	NOUN
admet-2338	109	5	were	be	AUX
admet-2338	109	6	reported	report	VERB
admet-2338	109	7	with	with	ADP
admet-2338	109	8	standard	standard	ADJ
admet-2338	109	9	deviation	deviation	NOUN
admet-2338	109	10	.	.	PUNCT
admet-2338	110	1	the	the	DET
admet-2338	110	2	disintegration	disintegration	NOUN
admet-2338	110	3	test	test	NOUN
admet-2338	110	4	was	be	AUX
admet-2338	110	5	performed	perform	VERB
admet-2338	110	6	using	use	VERB
admet-2338	110	7	the	the	DET
admet-2338	110	8	labindia	labindia	PROPN
admet-2338	110	9	-	-	PUNCT
admet-2338	110	10	dt1000	dt1000	PROPN
admet-2338	110	11	disintegration	disintegration	NOUN
admet-2338	110	12	tester	tester	NOUN
admet-2338	110	13	in	in	ADP
admet-2338	110	14	accordance	accordance	NOUN
admet-2338	110	15	with	with	ADP
admet-2338	110	16	the	the	DET
admet-2338	110	17	indian	indian	ADJ
admet-2338	110	18	pharmacopoeia	pharmacopoeia	NOUN
admet-2338	110	19	(	(	PUNCT
admet-2338	110	20	ip	ip	NOUN
admet-2338	110	21	)	)	PUNCT
admet-2338	110	22	in	in	ADP
admet-2338	110	23	distilled	distil	VERB
admet-2338	110	24	water	water	NOUN
admet-2338	110	25	at	at	ADP
admet-2338	110	26	37	37	NUM
admet-2338	110	27	°	°	NOUN
admet-2338	110	28	c	c	NOUN
admet-2338	110	29	.	.	PUNCT
admet-2338	111	1	the	the	DET
admet-2338	111	2	basket	basket	NOUN
admet-2338	111	3	's	's	PART
admet-2338	111	4	tubes	tube	NOUN
admet-2338	111	5	were	be	AUX
admet-2338	111	6	filled	fill	VERB
admet-2338	111	7	with	with	ADP
admet-2338	111	8	the	the	DET
admet-2338	111	9	tablets	tablet	NOUN
admet-2338	111	10	and	and	CCONJ
admet-2338	111	11	discs	disc	NOUN
admet-2338	111	12	were	be	AUX
admet-2338	111	13	placed	place	VERB
admet-2338	111	14	in	in	ADP
admet-2338	111	15	each	each	DET
admet-2338	111	16	basket	basket	NOUN
admet-2338	111	17	tube	tube	NOUN
admet-2338	111	18	.	.	PUNCT
admet-2338	112	1	the	the	DET
admet-2338	112	2	time	time	NOUN
admet-2338	112	3	was	be	AUX
admet-2338	112	4	noted	note	VERB
admet-2338	112	5	to	to	PART
admet-2338	112	6	complete	complete	VERB
admet-2338	112	7	disintegration	disintegration	NOUN
admet-2338	112	8	tablets	tablet	NOUN
admet-2338	112	9	.	.	PUNCT
admet-2338	113	1	the	the	DET
admet-2338	113	2	friability	friability	NOUN
admet-2338	113	3	test	test	NOUN
admet-2338	113	4	was	be	AUX
admet-2338	113	5	performed	perform	VERB
admet-2338	113	6	as	as	ADP
admet-2338	113	7	per	per	ADP
admet-2338	113	8	ip	ip	NOUN
admet-2338	113	9	,	,	PUNCT
admet-2338	113	10	the	the	DET
admet-2338	113	11	12	12	NUM
admet-2338	113	12	previously	previously	ADV
admet-2338	113	13	weighed	weigh	VERB
admet-2338	113	14	tablets	tablet	NOUN
admet-2338	113	15	were	be	AUX
admet-2338	113	16	placed	place	VERB
admet-2338	113	17	in	in	ADP
admet-2338	113	18	a	a	DET
admet-2338	113	19	roche	roche	PROPN
admet-2338	113	20	friability	friability	NOUN
admet-2338	113	21	tester	tester	NOUN
admet-2338	113	22	and	and	CCONJ
admet-2338	113	23	the	the	DET
admet-2338	113	24	friability	friability	NOUN
admet-2338	113	25	was	be	AUX
admet-2338	113	26	checked	check	VERB
admet-2338	113	27	at	at	ADP
admet-2338	113	28	25	25	NUM
admet-2338	113	29	rpm	rpm	NOUN
admet-2338	113	30	for	for	ADP
admet-2338	113	31	4	4	NUM
admet-2338	113	32	minutes	minute	NOUN
admet-2338	113	33	.	.	PUNCT
admet-2338	114	1	friability	friability	PROPN
admet-2338	114	2	was	be	AUX
admet-2338	114	3	calculated	calculate	VERB
admet-2338	114	4	as	as	ADP
admet-2338	114	5	f	f	PROPN
admet-2338	114	6	=	=	SYM
admet-2338	114	7	(	(	PUNCT
admet-2338	114	8	wi	wi	PROPN
admet-2338	114	9	-	-	PUNCT
admet-2338	114	10	wf)/wi	wf)/wi	NOUN
admet-2338	114	11	where	where	SCONJ
admet-2338	114	12	wi	wi	PROPN
admet-2338	114	13	=	=	SYM
admet-2338	114	14	initial	initial	ADJ
admet-2338	114	15	weight	weight	NOUN
admet-2338	114	16	of	of	ADP
admet-2338	114	17	tablets	tablet	NOUN
admet-2338	114	18	,	,	PUNCT
admet-2338	114	19	wf	wf	PROPN
admet-2338	114	20	=	=	PUNCT
admet-2338	114	21	final	final	ADJ
admet-2338	114	22	weight	weight	NOUN
admet-2338	114	23	of	of	ADP
admet-2338	114	24	tablets	tablet	NOUN
admet-2338	114	25	,	,	PUNCT
admet-2338	114	26	where	where	SCONJ
admet-2338	114	27	the	the	DET
admet-2338	114	28	friability	friability	NOUN
admet-2338	114	29	of	of	ADP
admet-2338	114	30	tablets	tablet	NOUN
admet-2338	114	31	less	less	ADJ
admet-2338	114	32	than	than	ADP
admet-2338	114	33	1	1	NUM
admet-2338	114	34	%	%	NOUN
admet-2338	114	35	was	be	AUX
admet-2338	114	36	considered	consider	VERB
admet-2338	114	37	acceptable	acceptable	ADJ
admet-2338	114	38	.	.	PUNCT
admet-2338	115	1	the	the	DET
admet-2338	115	2	weight	weight	NOUN
admet-2338	115	3	variation	variation	NOUN
admet-2338	115	4	was	be	AUX
admet-2338	115	5	calculated	calculate	VERB
admet-2338	115	6	per	per	ADP
admet-2338	115	7	ip	ip	NOUN
admet-2338	115	8	by	by	ADP
admet-2338	115	9	weighing	weigh	VERB
admet-2338	115	10	20	20	NUM
admet-2338	115	11	randomly	randomly	ADV
admet-2338	115	12	selected	select	VERB
admet-2338	115	13	tablets	tablet	NOUN
admet-2338	115	14	;	;	PUNCT
admet-2338	115	15	the	the	DET
admet-2338	115	16	average	average	ADJ
admet-2338	115	17	weight	weight	NOUN
admet-2338	115	18	and	and	CCONJ
admet-2338	115	19	standard	standard	ADJ
admet-2338	115	20	deviation	deviation	NOUN
admet-2338	115	21	were	be	AUX
admet-2338	115	22	calculated	calculate	VERB
admet-2338	115	23	.	.	PUNCT
admet-2338	116	1	in	in	ADP
admet-2338	116	2	vitro	vitro	X
admet-2338	116	3	dissolution	dissolution	PROPN
admet-2338	116	4	studies	study	NOUN
admet-2338	116	5	the	the	DET
admet-2338	116	6	in	in	ADP
admet-2338	116	7	vitro	vitro	X
admet-2338	116	8	dissolution	dissolution	NOUN
admet-2338	116	9	study	study	NOUN
admet-2338	116	10	was	be	AUX
admet-2338	116	11	carried	carry	VERB
admet-2338	116	12	out	out	ADP
admet-2338	116	13	using	use	VERB
admet-2338	116	14	usp	usp	PROPN
admet-2338	116	15	apparatus	apparatus	PROPN
admet-2338	116	16	ii	ii	PROPN
admet-2338	116	17	(	(	PUNCT
admet-2338	116	18	paddle	paddle	NOUN
admet-2338	116	19	type	type	NOUN
admet-2338	116	20	)	)	PUNCT
admet-2338	116	21	dissolution	dissolution	NOUN
admet-2338	116	22	apparatus	apparatus	NOUN
admet-2338	116	23	(	(	PUNCT
admet-2338	116	24	electrolab	electrolab	NOUN
admet-2338	116	25	tdt06l	tdt06l	NUM
admet-2338	116	26	)	)	PUNCT
admet-2338	116	27	.	.	PUNCT
admet-2338	117	1	the	the	DET
admet-2338	117	2	sfn	sfn	PROPN
admet-2338	117	3	-	-	PUNCT
admet-2338	117	4	ssd	ssd	PROPN
admet-2338	117	5	and	and	CCONJ
admet-2338	117	6	sfn	sfn	PROPN
admet-2338	117	7	instant	instant	ADJ
admet-2338	117	8	tablet	tablet	NOUN
admet-2338	117	9	was	be	AUX
admet-2338	117	10	placed	place	VERB
admet-2338	117	11	in	in	ADP
admet-2338	117	12	dissolution	dissolution	ADJ
admet-2338	117	13	vessels	vessel	NOUN
admet-2338	117	14	containing	contain	VERB
admet-2338	117	15	900	900	NUM
admet-2338	117	16	ml	ml	NOUN
admet-2338	117	17	of	of	ADP
admet-2338	117	18	0.1	0.1	NUM
admet-2338	117	19	m	m	NOUN
admet-2338	117	20	hcl	hcl	PROPN
admet-2338	117	21	at	at	ADP
admet-2338	117	22	37	37	NUM
admet-2338	117	23	±	±	NUM
admet-2338	117	24	0.5	0.5	NUM
admet-2338	117	25	°	°	ADP
admet-2338	117	26	c	c	NOUN
admet-2338	117	27	and	and	CCONJ
admet-2338	117	28	stirred	stir	VERB
admet-2338	117	29	at	at	ADP
admet-2338	117	30	75	75	NUM
admet-2338	117	31	rpm	rpm	NOUN
admet-2338	117	32	.	.	PUNCT
admet-2338	118	1	periodically	periodically	ADV
admet-2338	118	2	,	,	PUNCT
admet-2338	118	3	five	five	NUM
admet-2338	118	4	millilitres	millilitre	NOUN
admet-2338	118	5	of	of	ADP
admet-2338	118	6	the	the	DET
admet-2338	118	7	sample	sample	NOUN
admet-2338	118	8	were	be	AUX
admet-2338	118	9	taken	take	VERB
admet-2338	118	10	out	out	ADP
admet-2338	118	11	from	from	ADP
admet-2338	118	12	the	the	DET
admet-2338	118	13	dissolution	dissolution	NOUN
admet-2338	118	14	media	medium	NOUN
admet-2338	118	15	and	and	CCONJ
admet-2338	118	16	replaced	replace	VERB
admet-2338	118	17	with	with	ADP
admet-2338	118	18	fresh	fresh	ADJ
admet-2338	118	19	medium	medium	NOUN
admet-2338	118	20	.	.	PUNCT
admet-2338	119	1	three	three	NUM
admet-2338	119	2	duplicates	duplicate	NOUN
admet-2338	119	3	of	of	ADP
admet-2338	119	4	each	each	DET
admet-2338	119	5	dissolution	dissolution	NOUN
admet-2338	119	6	were	be	AUX
admet-2338	119	7	performed	perform	VERB
admet-2338	119	8	.	.	PUNCT
admet-2338	120	1	the	the	DET
admet-2338	120	2	samples	sample	NOUN
admet-2338	120	3	were	be	AUX
admet-2338	120	4	filtered	filter	VERB
admet-2338	120	5	using	use	VERB
admet-2338	120	6	a	a	DET
admet-2338	120	7	0.45	0.45	NUM
admet-2338	120	8	µm	µm	ADP
admet-2338	120	9	syringe	syringe	NOUN
admet-2338	120	10	filter	filter	NOUN
admet-2338	120	11	,	,	PUNCT
admet-2338	120	12	and	and	CCONJ
admet-2338	120	13	the	the	DET
admet-2338	120	14	amount	amount	NOUN
admet-2338	120	15	of	of	ADP
admet-2338	120	16	sfn	sfn	PROPN
admet-2338	120	17	dissolved	dissolve	VERB
admet-2338	120	18	in	in	ADP
admet-2338	120	19	each	each	DET
admet-2338	120	20	sample	sample	NOUN
admet-2338	120	21	was	be	AUX
admet-2338	120	22	measured	measure	VERB
admet-2338	120	23	using	use	VERB
admet-2338	120	24	uv	uv	NOUN
admet-2338	120	25	spectroscopy	spectroscopy	NOUN
admet-2338	120	26	at	at	ADP
admet-2338	120	27	max	max	PROPN
admet-2338	120	28	265	265	NUM
admet-2338	120	29	nm	nm	NOUN
admet-2338	120	30	.	.	PUNCT
admet-2338	121	1	analysis	analysis	NOUN
admet-2338	121	2	of	of	ADP
admet-2338	121	3	data	datum	NOUN
admet-2338	121	4	was	be	AUX
admet-2338	121	5	performed	perform	VERB
admet-2338	121	6	using	use	VERB
admet-2338	121	7	pcp	pcp	PROPN
admet-2338	121	8	disso	disso	PROPN
admet-2338	121	9	v3	v3	PROPN
admet-2338	121	10	(	(	PUNCT
admet-2338	121	11	pune	pune	NOUN
admet-2338	121	12	)	)	PUNCT
admet-2338	121	13	software	software	NOUN
admet-2338	121	14	.	.	PUNCT
admet-2338	122	1	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	PROPN
admet-2338	122	2	b.	b.	PROPN
admet-2338	122	3	kumar	kumar	PROPN
admet-2338	122	4	panda	panda	PROPN
admet-2338	122	5	et	et	PROPN
admet-2338	122	6	al	al	PROPN
admet-2338	122	7	.	.	PROPN
admet-2338	122	8	admet	admet	PROPN
admet-2338	122	9	&	&	CCONJ
admet-2338	122	10	dmpk	dmpk	PROPN
admet-2338	122	11	12(4	12(4	PROPN
admet-2338	122	12	)	)	PUNCT
admet-2338	122	13	(	(	PUNCT
admet-2338	122	14	2024	2024	NUM
admet-2338	122	15	)	)	PUNCT
admet-2338	122	16	687	687	NUM
admet-2338	122	17	-	-	SYM
admet-2338	122	18	702	702	NUM
admet-2338	122	19	692	692	NUM
admet-2338	122	20	bioanalytical	bioanalytical	ADJ
admet-2338	122	21	method	method	NOUN
admet-2338	122	22	of	of	ADP
admet-2338	122	23	sorafenib	sorafenib	NOUN
admet-2338	122	24	tosylate	tosylate	VERB
admet-2338	122	25	in	in	ADP
admet-2338	122	26	rat	rat	NOUN
admet-2338	122	27	plasma	plasma	NOUN
admet-2338	122	28	sfn	sfn	PROPN
admet-2338	122	29	was	be	AUX
admet-2338	122	30	assessed	assess	VERB
admet-2338	122	31	in	in	ADP
admet-2338	122	32	rat	rat	NOUN
admet-2338	122	33	plasma	plasma	NOUN
admet-2338	122	34	by	by	ADP
admet-2338	122	35	high	high	ADJ
admet-2338	122	36	-	-	PUNCT
admet-2338	122	37	performance	performance	NOUN
admet-2338	122	38	liquid	liquid	ADJ
admet-2338	122	39	chromatography	chromatography	NOUN
admet-2338	122	40	(	(	PUNCT
admet-2338	122	41	hplc	hplc	PROPN
admet-2338	122	42	)	)	PUNCT
admet-2338	122	43	.	.	PUNCT
admet-2338	123	1	the	the	DET
admet-2338	123	2	calibration	calibration	NOUN
admet-2338	123	3	of	of	ADP
admet-2338	123	4	sfn	sfn	PROPN
admet-2338	123	5	in	in	ADP
admet-2338	123	6	rat	rat	NOUN
admet-2338	123	7	plasma	plasma	NOUN
admet-2338	123	8	was	be	AUX
admet-2338	123	9	done	do	VERB
admet-2338	123	10	using	use	VERB
admet-2338	123	11	a	a	DET
admet-2338	123	12	jasco	jasco	ADJ
admet-2338	123	13	hplc	hplc	NOUN
admet-2338	123	14	(	(	PUNCT
admet-2338	123	15	jasco	jasco	PROPN
admet-2338	123	16	pu	pu	PROPN
admet-2338	123	17	1580	1580	NUM
admet-2338	123	18	,	,	PUNCT
admet-2338	123	19	uv-2075	uv-2075	ADJ
admet-2338	123	20	plus	plus	NOUN
admet-2338	123	21	,	,	PUNCT
admet-2338	123	22	japan	japan	PROPN
admet-2338	123	23	)	)	PUNCT
admet-2338	123	24	system	system	NOUN
admet-2338	123	25	with	with	ADP
admet-2338	123	26	a	a	DET
admet-2338	123	27	uv	uv	NOUN
admet-2338	123	28	detector	detector	NOUN
admet-2338	123	29	,	,	PUNCT
admet-2338	123	30	and	and	CCONJ
admet-2338	123	31	data	datum	NOUN
admet-2338	123	32	was	be	AUX
admet-2338	123	33	analysed	analyse	VERB
admet-2338	123	34	using	use	VERB
admet-2338	123	35	jasco	jasco	PROPN
admet-2338	123	36	borwin	borwin	PROPN
admet-2338	123	37	software	software	NOUN
admet-2338	123	38	.	.	PUNCT
admet-2338	124	1	the	the	DET
admet-2338	124	2	separation	separation	NOUN
admet-2338	124	3	was	be	AUX
admet-2338	124	4	done	do	VERB
admet-2338	124	5	using	use	VERB
admet-2338	124	6	a	a	DET
admet-2338	124	7	reversed	reverse	VERB
admet-2338	124	8	-	-	PUNCT
admet-2338	124	9	phase	phase	NOUN
admet-2338	124	10	c18	c18	NOUN
admet-2338	124	11	column	column	NOUN
admet-2338	124	12	(	(	PUNCT
admet-2338	124	13	5	5	NUM
admet-2338	124	14	µm	µm	NOUN
admet-2338	124	15	,	,	PUNCT
admet-2338	124	16	250×4.6	250×4.6	NUM
admet-2338	124	17	mm	mm	NOUN
admet-2338	124	18	,	,	PUNCT
admet-2338	124	19	mz	mz	PROPN
admet-2338	124	20	-	-	ADJ
admet-2338	124	21	analytical	analytical	ADJ
admet-2338	124	22	,	,	PUNCT
admet-2338	124	23	germany	germany	PROPN
admet-2338	124	24	)	)	PUNCT
admet-2338	124	25	with	with	ADP
admet-2338	124	26	an	an	DET
admet-2338	124	27	attached	attached	ADJ
admet-2338	124	28	guard	guard	NOUN
admet-2338	124	29	column	column	NOUN
admet-2338	124	30	(	(	PUNCT
admet-2338	124	31	shodex	shodex	PROPN
admet-2338	124	32	ohpak	ohpak	PROPN
admet-2338	124	33	sb	sb	PROPN
admet-2338	124	34	-	-	NOUN
admet-2338	124	35	g	g	NOUN
admet-2338	124	36	)	)	PUNCT
admet-2338	124	37	at	at	ADP
admet-2338	124	38	room	room	NOUN
admet-2338	124	39	temperature	temperature	NOUN
admet-2338	124	40	.	.	PUNCT
admet-2338	125	1	the	the	DET
admet-2338	125	2	composition	composition	NOUN
admet-2338	125	3	of	of	ADP
admet-2338	125	4	the	the	DET
admet-2338	125	5	mobile	mobile	ADJ
admet-2338	125	6	phase	phase	NOUN
admet-2338	125	7	was	be	AUX
admet-2338	125	8	acetonitrile	acetonitrile	ADJ
admet-2338	125	9	,	,	PUNCT
admet-2338	125	10	methanol	methanol	NOUN
admet-2338	125	11	,	,	PUNCT
admet-2338	125	12	and	and	CCONJ
admet-2338	125	13	1	1	NUM
admet-2338	125	14	%	%	NOUN
admet-2338	125	15	acetic	acetic	ADJ
admet-2338	125	16	acid	acid	NOUN
admet-2338	125	17	(	(	PUNCT
admet-2338	125	18	35:40:25	35:40:25	NUM
admet-2338	125	19	v	v	NOUN
admet-2338	125	20	/	/	SYM
admet-2338	125	21	v	v	NOUN
admet-2338	125	22	)	)	PUNCT
admet-2338	125	23	at	at	ADP
admet-2338	125	24	a	a	DET
admet-2338	125	25	flow	flow	NOUN
admet-2338	125	26	rate	rate	NOUN
admet-2338	125	27	of	of	ADP
admet-2338	125	28	1	1	NUM
admet-2338	125	29	ml	ml	NOUN
admet-2338	125	30	/	/	SYM
admet-2338	125	31	min	min	NOUN
admet-2338	125	32	with	with	ADP
admet-2338	125	33	an	an	DET
admet-2338	125	34	injection	injection	NOUN
admet-2338	125	35	volume	volume	NOUN
admet-2338	125	36	of	of	ADP
admet-2338	125	37	20	20	NUM
admet-2338	125	38	µl	µl	NOUN
admet-2338	125	39	.	.	PUNCT
admet-2338	126	1	the	the	DET
admet-2338	126	2	sfn	sfn	PROPN
admet-2338	126	3	eluent	eluent	NOUN
admet-2338	126	4	was	be	AUX
admet-2338	126	5	monitored	monitor	VERB
admet-2338	126	6	at	at	ADP
admet-2338	126	7	265	265	NUM
admet-2338	126	8	nm	nm	NOUN
admet-2338	126	9	.	.	PUNCT
admet-2338	127	1	the	the	DET
admet-2338	127	2	sfn	sfn	PROPN
admet-2338	127	3	analysis	analysis	NOUN
admet-2338	127	4	was	be	AUX
admet-2338	127	5	adapted	adapt	VERB
admet-2338	127	6	from	from	ADP
admet-2338	127	7	a	a	DET
admet-2338	127	8	previously	previously	ADV
admet-2338	127	9	developed	develop	VERB
admet-2338	127	10	method	method	NOUN
admet-2338	127	11	with	with	ADP
admet-2338	127	12	a	a	DET
admet-2338	127	13	slight	slight	ADJ
admet-2338	127	14	modification	modification	NOUN
admet-2338	127	15	[	[	X
admet-2338	127	16	5	5	NUM
admet-2338	127	17	]	]	PUNCT
admet-2338	127	18	.	.	PUNCT
admet-2338	128	1	briefly	briefly	NOUN
admet-2338	128	2	,	,	PUNCT
admet-2338	128	3	in	in	ADP
admet-2338	128	4	150	150	NUM
admet-2338	128	5	µl	µl	NOUN
admet-2338	128	6	of	of	ADP
admet-2338	128	7	fresh	fresh	ADJ
admet-2338	128	8	plasma	plasma	NOUN
admet-2338	128	9	,	,	PUNCT
admet-2338	128	10	an	an	DET
admet-2338	128	11	aliquot	aliquot	NOUN
admet-2338	128	12	of	of	ADP
admet-2338	128	13	150	150	NUM
admet-2338	128	14	µl	µl	NOUN
admet-2338	128	15	of	of	ADP
admet-2338	128	16	sfn	sfn	NOUN
admet-2338	128	17	solution	solution	NOUN
admet-2338	128	18	was	be	AUX
admet-2338	128	19	added	add	VERB
admet-2338	128	20	.	.	PUNCT
admet-2338	129	1	the	the	DET
admet-2338	129	2	500	500	NUM
admet-2338	129	3	µl	µl	NOUN
admet-2338	129	4	of	of	ADP
admet-2338	129	5	extracting	extract	VERB
admet-2338	129	6	solvent	solvent	ADJ
admet-2338	129	7	methanol	methanol	NOUN
admet-2338	129	8	:	:	PUNCT
admet-2338	129	9	acetonitrile	acetonitrile	NOUN
admet-2338	129	10	(	(	PUNCT
admet-2338	129	11	4	4	NUM
admet-2338	129	12	:	:	SYM
admet-2338	129	13	1	1	NUM
admet-2338	129	14	)	)	PUNCT
admet-2338	129	15	was	be	AUX
admet-2338	129	16	added	add	VERB
admet-2338	129	17	to	to	ADP
admet-2338	129	18	the	the	DET
admet-2338	129	19	above	above	ADJ
admet-2338	129	20	solution	solution	NOUN
admet-2338	129	21	,	,	PUNCT
admet-2338	129	22	vortexed	vortexe	VERB
admet-2338	129	23	(	(	PUNCT
admet-2338	129	24	spinex	spinex	NOUN
admet-2338	129	25	)	)	PUNCT
admet-2338	129	26	,	,	PUNCT
admet-2338	129	27	and	and	CCONJ
admet-2338	129	28	sonicated	sonicate	VERB
admet-2338	129	29	(	(	PUNCT
admet-2338	129	30	athena	athena	NOUN
admet-2338	129	31	-	-	PUNCT
admet-2338	129	32	ats2lcd	ats2lcd	NOUN
admet-2338	129	33	)	)	PUNCT
admet-2338	129	34	for	for	ADP
admet-2338	129	35	20	20	NUM
admet-2338	129	36	min	min	NOUN
admet-2338	129	37	.	.	PUNCT
admet-2338	130	1	the	the	DET
admet-2338	130	2	precipitated	precipitate	VERB
admet-2338	130	3	plasma	plasma	NOUN
admet-2338	130	4	was	be	AUX
admet-2338	130	5	separated	separate	VERB
admet-2338	130	6	by	by	ADP
admet-2338	130	7	centrifuging	centrifuge	VERB
admet-2338	130	8	at	at	ADP
admet-2338	130	9	15000	15000	NUM
admet-2338	130	10	rpm	rpm	NOUN
admet-2338	130	11	at	at	ADP
admet-2338	130	12	4	4	NUM
admet-2338	130	13	°	°	ADP
admet-2338	130	14	c	c	NOUN
admet-2338	130	15	for	for	ADP
admet-2338	130	16	20	20	NUM
admet-2338	130	17	min	min	PROPN
admet-2338	130	18	(	(	PUNCT
admet-2338	130	19	eppendorf-5424r	eppendorf-5424r	PROPN
admet-2338	130	20	)	)	PUNCT
admet-2338	130	21	.	.	PUNCT
admet-2338	131	1	the	the	DET
admet-2338	131	2	supernatant	supernatant	NOUN
admet-2338	131	3	was	be	AUX
admet-2338	131	4	separated	separate	VERB
admet-2338	131	5	,	,	PUNCT
admet-2338	131	6	filtered	filter	VERB
admet-2338	131	7	through	through	ADP
admet-2338	131	8	a	a	DET
admet-2338	131	9	0.2	0.2	NUM
admet-2338	131	10	μm	μm	NUM
admet-2338	131	11	syringe	syringe	NOUN
admet-2338	131	12	filter	filter	NOUN
admet-2338	131	13	,	,	PUNCT
admet-2338	131	14	and	and	CCONJ
admet-2338	131	15	injected	inject	VERB
admet-2338	131	16	into	into	ADP
admet-2338	131	17	hplc	hplc	NOUN
admet-2338	131	18	[	[	X
admet-2338	131	19	14	14	NUM
admet-2338	131	20	]	]	PUNCT
admet-2338	131	21	.	.	PUNCT
admet-2338	132	1	animals	animal	NOUN
admet-2338	132	2	a	a	DET
admet-2338	132	3	total	total	NOUN
admet-2338	132	4	of	of	ADP
admet-2338	132	5	24	24	NUM
admet-2338	132	6	male	male	NOUN
admet-2338	132	7	wistar	wistar	PROPN
admet-2338	132	8	rats	rat	NOUN
admet-2338	132	9	(	(	PUNCT
admet-2338	132	10	200	200	NUM
admet-2338	132	11	-	-	SYM
admet-2338	132	12	220	220	NUM
admet-2338	132	13	g	g	NOUN
admet-2338	132	14	)	)	PUNCT
admet-2338	132	15	were	be	AUX
admet-2338	132	16	procured	procure	VERB
admet-2338	132	17	from	from	ADP
admet-2338	132	18	the	the	DET
admet-2338	132	19	national	national	PROPN
admet-2338	132	20	institute	institute	PROPN
admet-2338	132	21	of	of	ADP
admet-2338	132	22	biosciences	bioscience	NOUN
admet-2338	132	23	,	,	PUNCT
admet-2338	132	24	1091	1091	NUM
admet-2338	132	25	/	/	SYM
admet-2338	132	26	abc/07	abc/07	ADJ
admet-2338	132	27	/	/	SYM
admet-2338	132	28	cpcsea	cpcsea	NOUN
admet-2338	132	29	.	.	PUNCT
admet-2338	133	1	the	the	DET
admet-2338	133	2	experimental	experimental	ADJ
admet-2338	133	3	protocol	protocol	NOUN
admet-2338	133	4	was	be	AUX
admet-2338	133	5	approved	approve	VERB
admet-2338	133	6	by	by	ADP
admet-2338	133	7	the	the	DET
admet-2338	133	8	institutional	institutional	ADJ
admet-2338	133	9	animal	animal	NOUN
admet-2338	133	10	ethics	ethic	NOUN
admet-2338	133	11	committee	committee	NOUN
admet-2338	133	12	(	(	PUNCT
admet-2338	133	13	iaec	iaec	NOUN
admet-2338	133	14	)	)	PUNCT
admet-2338	133	15	of	of	ADP
admet-2338	133	16	poona	poona	PROPN
admet-2338	133	17	college	college	PROPN
admet-2338	133	18	of	of	ADP
admet-2338	133	19	pharmacy	pharmacy	NOUN
admet-2338	133	20	(	(	PUNCT
admet-2338	133	21	iaec	iaec	ADV
admet-2338	133	22	no	no	INTJ
admet-2338	133	23	.	.	PROPN
admet-2338	133	24	1703	1703	NUM
admet-2338	133	25	/	/	SYM
admet-2338	133	26	po	po	NOUN
admet-2338	133	27	/	/	SYM
admet-2338	133	28	re	re	ADJ
admet-2338	133	29	/	/	SYM
admet-2338	133	30	s/01	s/01	ADJ
admet-2338	133	31	/	/	SYM
admet-2338	133	32	cpcsea	cpcsea	NOUN
admet-2338	133	33	)	)	PUNCT
admet-2338	133	34	,	,	PUNCT
admet-2338	133	35	bharti	bharti	PROPN
admet-2338	133	36	vidyapeeth	vidyapeeth	PROPN
admet-2338	133	37	deemed	deem	VERB
admet-2338	133	38	university	university	PROPN
admet-2338	133	39	.	.	PUNCT
admet-2338	134	1	the	the	DET
admet-2338	134	2	protocol	protocol	NOUN
admet-2338	134	3	approval	approval	NOUN
admet-2338	134	4	no	no	INTJ
admet-2338	134	5	.	.	PUNCT
admet-2338	134	6	is	be	AUX
admet-2338	134	7	cpcsea	cpcsea	PROPN
admet-2338	134	8	/	/	SYM
admet-2338	134	9	pcp	pcp	PROPN
admet-2338	134	10	/	/	SYM
admet-2338	134	11	pct22/2018	pct22/2018	NOUN
admet-2338	134	12	-	-	NUM
admet-2338	134	13	19	19	NUM
admet-2338	134	14	,	,	PUNCT
admet-2338	134	15	along	along	ADP
admet-2338	134	16	with	with	ADP
admet-2338	134	17	arrive	arrive	ADJ
admet-2338	134	18	cpcsea	cpcsea	NOUN
admet-2338	134	19	and	and	CCONJ
admet-2338	134	20	arrive	arrive	ADJ
admet-2338	134	21	guidelines	guideline	NOUN
admet-2338	134	22	(	(	PUNCT
admet-2338	134	23	2.0	2.0	NUM
admet-2338	134	24	version	version	NOUN
admet-2338	134	25	)	)	PUNCT
admet-2338	134	26	.	.	PUNCT
admet-2338	135	1	the	the	DET
admet-2338	135	2	care	care	NOUN
admet-2338	135	3	and	and	CCONJ
admet-2338	135	4	use	use	NOUN
admet-2338	135	5	of	of	ADP
admet-2338	135	6	experimental	experimental	ADJ
admet-2338	135	7	animals	animal	NOUN
admet-2338	135	8	were	be	AUX
admet-2338	135	9	as	as	ADP
admet-2338	135	10	per	per	ADP
admet-2338	135	11	cpcsea	cpcsea	NOUN
admet-2338	135	12	guidelines	guideline	NOUN
admet-2338	135	13	.	.	PUNCT
admet-2338	136	1	the	the	DET
admet-2338	136	2	sample	sample	NOUN
admet-2338	136	3	size	size	NOUN
admet-2338	136	4	of	of	ADP
admet-2338	136	5	n	n	NOUN
admet-2338	136	6	=	=	SYM
admet-2338	136	7	12	12	NUM
admet-2338	136	8	animals	animal	NOUN
admet-2338	136	9	/	/	SYM
admet-2338	136	10	group	group	NOUN
admet-2338	136	11	was	be	AUX
admet-2338	136	12	selected	select	VERB
admet-2338	136	13	.	.	PUNCT
admet-2338	137	1	the	the	DET
admet-2338	137	2	randomization	randomization	NOUN
admet-2338	137	3	of	of	ADP
admet-2338	137	4	animals	animal	NOUN
admet-2338	137	5	in	in	ADP
admet-2338	137	6	different	different	ADJ
admet-2338	137	7	groups	group	NOUN
admet-2338	137	8	was	be	AUX
admet-2338	137	9	done	do	VERB
admet-2338	137	10	by	by	ADP
admet-2338	137	11	using	use	VERB
admet-2338	137	12	the	the	DET
admet-2338	137	13	software	software	NOUN
admet-2338	137	14	graph	graph	NOUN
admet-2338	137	15	prism	prism	NOUN
admet-2338	137	16	tool	tool	NOUN
admet-2338	137	17	.	.	PUNCT
admet-2338	138	1	the	the	DET
admet-2338	138	2	observations	observation	NOUN
admet-2338	138	3	were	be	AUX
admet-2338	138	4	recorded	record	VERB
admet-2338	138	5	by	by	ADP
admet-2338	138	6	the	the	DET
admet-2338	138	7	observer	observer	NOUN
admet-2338	138	8	,	,	PUNCT
admet-2338	138	9	who	who	PRON
admet-2338	138	10	was	be	AUX
admet-2338	138	11	blind	blind	ADJ
admet-2338	138	12	to	to	ADP
admet-2338	138	13	the	the	DET
admet-2338	138	14	treatments	treatment	NOUN
admet-2338	138	15	.	.	PUNCT
admet-2338	139	1	the	the	DET
admet-2338	139	2	animals	animal	NOUN
admet-2338	139	3	were	be	AUX
admet-2338	139	4	housed	house	VERB
admet-2338	139	5	in	in	ADP
admet-2338	139	6	12	12	NUM
admet-2338	139	7	hour	hour	NOUN
admet-2338	139	8	alternative	alternative	ADJ
admet-2338	139	9	light	light	ADJ
admet-2338	139	10	and	and	CCONJ
admet-2338	139	11	dark	dark	ADJ
admet-2338	139	12	cycles	cycle	NOUN
admet-2338	139	13	at	at	ADP
admet-2338	139	14	24	24	NUM
admet-2338	139	15	°	°	NOUN
admet-2338	139	16	c	c	NOUN
admet-2338	139	17	temperature	temperature	NOUN
admet-2338	139	18	and	and	CCONJ
admet-2338	139	19	55	55	NUM
admet-2338	139	20	%	%	NOUN
admet-2338	139	21	relative	relative	ADJ
admet-2338	139	22	humidity	humidity	NOUN
admet-2338	139	23	.	.	PUNCT
admet-2338	140	1	the	the	DET
admet-2338	140	2	animals	animal	NOUN
admet-2338	140	3	were	be	AUX
admet-2338	140	4	given	give	VERB
admet-2338	140	5	access	access	NOUN
admet-2338	140	6	to	to	ADP
admet-2338	140	7	standard	standard	ADJ
admet-2338	140	8	food	food	NOUN
admet-2338	140	9	pellets	pellet	NOUN
admet-2338	140	10	and	and	CCONJ
admet-2338	140	11	filtered	filter	VERB
admet-2338	140	12	water	water	NOUN
admet-2338	140	13	[	[	X
admet-2338	140	14	16	16	NUM
admet-2338	140	15	]	]	PUNCT
admet-2338	140	16	.	.	PUNCT
admet-2338	141	1	in	in	ADP
admet-2338	141	2	vivo	vivo	ADJ
admet-2338	141	3	pharmacokinetics	pharmacokinetic	NOUN
admet-2338	141	4	study	study	NOUN
admet-2338	141	5	in	in	ADP
admet-2338	141	6	rats	rat	NOUN
admet-2338	141	7	the	the	DET
admet-2338	141	8	pharmacokinetic	pharmacokinetic	ADJ
admet-2338	141	9	study	study	NOUN
admet-2338	141	10	was	be	AUX
admet-2338	141	11	conducted	conduct	VERB
admet-2338	141	12	in	in	ADP
admet-2338	141	13	24	24	NUM
admet-2338	141	14	male	male	ADJ
admet-2338	141	15	wistar	wistar	PROPN
admet-2338	141	16	rats	rat	NOUN
admet-2338	141	17	where	where	SCONJ
admet-2338	141	18	animals	animal	NOUN
admet-2338	141	19	were	be	AUX
admet-2338	141	20	divided	divide	VERB
admet-2338	141	21	into	into	ADP
admet-2338	141	22	two	two	NUM
admet-2338	141	23	groups	group	NOUN
admet-2338	141	24	(	(	PUNCT
admet-2338	141	25	n	n	NOUN
admet-2338	141	26	=	=	NUM
admet-2338	141	27	12	12	NUM
admet-2338	141	28	)	)	PUNCT
admet-2338	141	29	.	.	PUNCT
admet-2338	142	1	group	group	NOUN
admet-2338	142	2	i	i	PRON
admet-2338	142	3	received	receive	VERB
admet-2338	142	4	pure	pure	ADJ
admet-2338	142	5	sfn	sfn	PROPN
admet-2338	142	6	(	(	PUNCT
admet-2338	142	7	20	20	NUM
admet-2338	142	8	mg	mg	NUM
admet-2338	142	9	/	/	SYM
admet-2338	142	10	kg	kg	NOUN
admet-2338	142	11	)	)	PUNCT
admet-2338	142	12	aqueous	aqueous	ADJ
admet-2338	142	13	suspension	suspension	NOUN
admet-2338	142	14	,	,	PUNCT
admet-2338	142	15	and	and	CCONJ
admet-2338	142	16	group	group	PROPN
admet-2338	142	17	ii	ii	PROPN
admet-2338	142	18	received	receive	VERB
admet-2338	142	19	sfn	sfn	PROPN
admet-2338	142	20	-	-	PUNCT
admet-2338	142	21	ssd	ssd	NOUN
admet-2338	142	22	(	(	PUNCT
admet-2338	142	23	equivalent	equivalent	ADJ
admet-2338	142	24	sfn	sfn	PROPN
admet-2338	142	25	20	20	NUM
admet-2338	142	26	mg	mg	PROPN
admet-2338	142	27	/	/	SYM
admet-2338	142	28	kg	kg	NOUN
admet-2338	142	29	)	)	PUNCT
admet-2338	142	30	orally	orally	ADV
admet-2338	143	1	[	[	X
admet-2338	143	2	16	16	NUM
admet-2338	143	3	]	]	PUNCT
admet-2338	143	4	.	.	PUNCT
admet-2338	144	1	the	the	DET
admet-2338	144	2	0.5	0.5	NUM
admet-2338	144	3	ml	ml	NOUN
admet-2338	144	4	of	of	ADP
admet-2338	144	5	blood	blood	NOUN
admet-2338	144	6	was	be	AUX
admet-2338	144	7	collected	collect	VERB
admet-2338	144	8	from	from	ADP
admet-2338	144	9	a	a	DET
admet-2338	144	10	retro	retro	ADJ
admet-2338	144	11	-	-	PUNCT
admet-2338	144	12	orbital	orbital	ADJ
admet-2338	144	13	puncture	puncture	NOUN
admet-2338	144	14	under	under	ADP
admet-2338	144	15	anaesthesia	anaesthesia	NOUN
admet-2338	144	16	by	by	ADP
admet-2338	144	17	thiopentone	thiopentone	NOUN
admet-2338	144	18	sodium	sodium	NOUN
admet-2338	144	19	(	(	PUNCT
admet-2338	144	20	45	45	NUM
admet-2338	144	21	mg	mg	PROPN
admet-2338	144	22	/	/	SYM
admet-2338	144	23	kg	kg	NOUN
admet-2338	144	24	)	)	PUNCT
admet-2338	144	25	at	at	ADP
admet-2338	144	26	0.5	0.5	NUM
admet-2338	144	27	,	,	PUNCT
admet-2338	144	28	1	1	NUM
admet-2338	144	29	,	,	PUNCT
admet-2338	144	30	2	2	NUM
admet-2338	144	31	,	,	PUNCT
admet-2338	144	32	4	4	NUM
admet-2338	144	33	,	,	PUNCT
admet-2338	144	34	8	8	NUM
admet-2338	144	35	,	,	PUNCT
admet-2338	144	36	12	12	NUM
admet-2338	144	37	,	,	PUNCT
admet-2338	144	38	24	24	NUM
admet-2338	144	39	,	,	PUNCT
admet-2338	144	40	6	6	NUM
admet-2338	144	41	and	and	CCONJ
admet-2338	144	42	48	48	NUM
admet-2338	144	43	-	-	PUNCT
admet-2338	144	44	hour	hour	NOUN
admet-2338	144	45	time	time	NOUN
admet-2338	144	46	intervals	interval	NOUN
admet-2338	144	47	into	into	ADP
admet-2338	144	48	edta	edta	NOUN
admet-2338	144	49	tubes	tubes	PROPN
admet-2338	144	50	.	.	PUNCT
admet-2338	145	1	plasma	plasma	PROPN
admet-2338	145	2	was	be	AUX
admet-2338	145	3	separated	separate	VERB
admet-2338	145	4	by	by	ADP
admet-2338	145	5	centrifuging	centrifuge	VERB
admet-2338	145	6	at	at	ADP
admet-2338	145	7	10,000	10,000	NUM
admet-2338	145	8	rpm	rpm	NOUN
admet-2338	145	9	for	for	ADP
admet-2338	145	10	15	15	NUM
admet-2338	145	11	min	min	NOUN
admet-2338	145	12	at	at	ADP
admet-2338	145	13	4	4	NUM
admet-2338	145	14	°	°	NOUN
admet-2338	145	15	c	c	NOUN
admet-2338	145	16	and	and	CCONJ
admet-2338	145	17	stored	store	VERB
admet-2338	145	18	in	in	ADP
admet-2338	145	19	a	a	DET
admet-2338	145	20	deep	deep	ADJ
admet-2338	145	21	freezer	freezer	NOUN
admet-2338	145	22	(	(	PUNCT
admet-2338	145	23	thermoscientific	thermoscientific	NOUN
admet-2338	145	24	-	-	PUNCT
admet-2338	145	25	exf24086v	exf24086v	NOUN
admet-2338	145	26	)	)	PUNCT
admet-2338	145	27	at	at	ADP
admet-2338	145	28	-20	-20	PROPN
admet-2338	145	29	°	°	ADP
admet-2338	145	30	c	c	NOUN
admet-2338	145	31	till	till	SCONJ
admet-2338	145	32	further	further	ADJ
admet-2338	145	33	analysis	analysis	NOUN
admet-2338	145	34	.	.	PUNCT
admet-2338	146	1	the	the	DET
admet-2338	146	2	amount	amount	NOUN
admet-2338	146	3	of	of	ADP
admet-2338	146	4	sfn	sfn	PROPN
admet-2338	146	5	in	in	ADP
admet-2338	146	6	plasma	plasma	NOUN
admet-2338	146	7	was	be	AUX
admet-2338	146	8	analysed	analyse	VERB
admet-2338	146	9	by	by	ADP
admet-2338	146	10	the	the	DET
admet-2338	146	11	previously	previously	ADV
admet-2338	146	12	described	describe	VERB
admet-2338	146	13	hplc	hplc	NOUN
admet-2338	146	14	method	method	NOUN
admet-2338	146	15	.	.	PUNCT
admet-2338	147	1	the	the	DET
admet-2338	147	2	assessment	assessment	NOUN
admet-2338	147	3	of	of	ADP
admet-2338	147	4	pharmacokinetic	pharmacokinetic	ADJ
admet-2338	147	5	parameters	parameter	NOUN
admet-2338	147	6	such	such	ADJ
admet-2338	147	7	as	as	ADP
admet-2338	147	8	area	area	NOUN
admet-2338	147	9	under	under	ADP
admet-2338	147	10	the	the	DET
admet-2338	147	11	curve	curve	NOUN
admet-2338	147	12	(	(	PUNCT
admet-2338	147	13	(	(	PUNCT
admet-2338	147	14	auc	auc	X
admet-2338	147	15	(	(	PUNCT
admet-2338	147	16	0	0	NUM
admet-2338	147	17	→	→	SYM
admet-2338	147	18	48	48	NUM
admet-2338	147	19	h	h	NOUN
admet-2338	147	20	)	)	PUNCT
admet-2338	147	21	)	)	PUNCT
admet-2338	147	22	,	,	PUNCT
admet-2338	147	23	elimination	elimination	NOUN
admet-2338	147	24	rate	rate	NOUN
admet-2338	147	25	constant	constant	ADJ
admet-2338	147	26	(	(	PUNCT
admet-2338	147	27	kel	kel	NOUN
admet-2338	147	28	)	)	PUNCT
admet-2338	147	29	)	)	PUNCT
admet-2338	147	30	,	,	PUNCT
admet-2338	147	31	maximum	maximum	ADJ
admet-2338	147	32	concentration	concentration	NOUN
admet-2338	147	33	(	(	PUNCT
admet-2338	147	34	cmax	cmax	NOUN
admet-2338	147	35	)	)	PUNCT
admet-2338	147	36	,	,	PUNCT
admet-2338	147	37	time	time	NOUN
admet-2338	147	38	to	to	PART
admet-2338	147	39	peak	peak	VERB
admet-2338	147	40	drug	drug	NOUN
admet-2338	147	41	concentration	concentration	NOUN
admet-2338	147	42	(	(	PUNCT
admet-2338	147	43	tmax	tmax	ADV
admet-2338	147	44	)	)	PUNCT
admet-2338	147	45	,	,	PUNCT
admet-2338	147	46	and	and	CCONJ
admet-2338	147	47	half	half	ADJ
admet-2338	147	48	-	-	PUNCT
admet-2338	147	49	life	life	NOUN
admet-2338	147	50	(	(	PUNCT
admet-2338	147	51	t1/2	t1/2	NOUN
admet-2338	147	52	)	)	PUNCT
admet-2338	147	53	were	be	AUX
admet-2338	147	54	calculated	calculate	VERB
admet-2338	147	55	by	by	ADP
admet-2338	147	56	noncompartmental	noncompartmental	ADJ
admet-2338	147	57	analysis	analysis	NOUN
admet-2338	147	58	using	use	VERB
admet-2338	147	59	pk	pk	NOUN
admet-2338	147	60	solver	solver	NOUN
admet-2338	147	61	®	®	NOUN
admet-2338	147	62	software	software	NOUN
admet-2338	147	63	(	(	PUNCT
admet-2338	147	64	version	version	NOUN
admet-2338	147	65	2.1	2.1	NUM
admet-2338	147	66	;	;	PUNCT
admet-2338	147	67	pharsight	pharsight	PROPN
admet-2338	147	68	co.	co.	PROPN
admet-2338	147	69	,	,	PUNCT
admet-2338	147	70	mountain	mountain	NOUN
admet-2338	147	71	view	view	NOUN
admet-2338	147	72	,	,	PUNCT
admet-2338	147	73	ca	ca	PROPN
admet-2338	147	74	,	,	PUNCT
admet-2338	147	75	usa	usa	PROPN
admet-2338	147	76	)	)	PUNCT
admet-2338	148	1	[	[	X
admet-2338	148	2	10,16	10,16	NUM
admet-2338	148	3	]	]	PUNCT
admet-2338	148	4	.	.	PUNCT
admet-2338	149	1	statistical	statistical	ADJ
admet-2338	149	2	analysis	analysis	NOUN
admet-2338	149	3	student	student	NOUN
admet-2338	149	4	’s	’s	PART
admet-2338	149	5	t	t	PROPN
admet-2338	149	6	-	-	PUNCT
admet-2338	149	7	test	test	NOUN
admet-2338	149	8	was	be	AUX
admet-2338	149	9	used	use	VERB
admet-2338	149	10	for	for	ADP
admet-2338	149	11	statistical	statistical	ADJ
admet-2338	149	12	analysis	analysis	NOUN
admet-2338	149	13	of	of	ADP
admet-2338	149	14	a	a	DET
admet-2338	149	15	sample	sample	NOUN
admet-2338	149	16	by	by	ADP
admet-2338	149	17	one	one	NUM
admet-2338	149	18	-	-	PUNCT
admet-2338	149	19	way	way	NOUN
admet-2338	149	20	analysis	analysis	NOUN
admet-2338	149	21	of	of	ADP
admet-2338	149	22	variance	variance	NOUN
admet-2338	149	23	(	(	PUNCT
admet-2338	149	24	anova	anova	PROPN
admet-2338	149	25	)	)	PUNCT
admet-2338	149	26	.	.	PUNCT
admet-2338	150	1	the	the	DET
admet-2338	150	2	results	result	NOUN
admet-2338	150	3	were	be	AUX
admet-2338	150	4	quoted	quote	VERB
admet-2338	150	5	as	as	ADV
admet-2338	150	6	significant	significant	ADJ
admet-2338	150	7	if	if	SCONJ
admet-2338	150	8	p	p	X
admet-2338	150	9	<	<	X
admet-2338	150	10	0.05	0.05	NUM
admet-2338	150	11	.	.	PUNCT
admet-2338	151	1	all	all	DET
admet-2338	151	2	data	datum	NOUN
admet-2338	151	3	were	be	AUX
admet-2338	151	4	given	give	VERB
admet-2338	151	5	as	as	ADP
admet-2338	151	6	mean	mean	PROPN
admet-2338	151	7	±	±	NUM
admet-2338	151	8	standard	standard	ADJ
admet-2338	151	9	deviation	deviation	NOUN
admet-2338	151	10	.	.	PUNCT
admet-2338	152	1	(	(	PUNCT
admet-2338	152	2	graphpad	graphpad	NOUN
admet-2338	152	3	prism	prism	NOUN
admet-2338	152	4	v8.0.2	v8.0.2	NOUN
admet-2338	152	5	,	,	PUNCT
admet-2338	152	6	usa	usa	PROPN
admet-2338	152	7	)	)	PUNCT
admet-2338	152	8	.	.	PUNCT
admet-2338	153	1	results	result	NOUN
admet-2338	153	2	and	and	CCONJ
admet-2338	153	3	discussion	discussion	NOUN
admet-2338	153	4	saturation	saturation	NOUN
admet-2338	153	5	solubility	solubility	NOUN
admet-2338	153	6	study	study	VERB
admet-2338	153	7	the	the	DET
admet-2338	153	8	saturation	saturation	NOUN
admet-2338	153	9	solubility	solubility	NOUN
admet-2338	153	10	was	be	AUX
admet-2338	153	11	performed	perform	VERB
admet-2338	153	12	in	in	ADP
admet-2338	153	13	different	different	ADJ
admet-2338	153	14	solvents	solvent	NOUN
admet-2338	153	15	to	to	PART
admet-2338	153	16	select	select	VERB
admet-2338	153	17	the	the	DET
admet-2338	153	18	suitable	suitable	ADJ
admet-2338	153	19	solvent	solvent	NOUN
admet-2338	153	20	for	for	ADP
admet-2338	153	21	ssd	ssd	NOUN
admet-2338	153	22	preparation	preparation	NOUN
admet-2338	153	23	.	.	PUNCT
admet-2338	154	1	as	as	SCONJ
admet-2338	154	2	shown	show	VERB
admet-2338	154	3	in	in	ADP
admet-2338	154	4	figure	figure	NOUN
admet-2338	154	5	2a	2a	NUM
admet-2338	154	6	,	,	PUNCT
admet-2338	154	7	the	the	DET
admet-2338	154	8	sfn	sfn	NOUN
admet-2338	154	9	showed	show	VERB
admet-2338	154	10	very	very	ADV
admet-2338	154	11	slight	slight	ADJ
admet-2338	154	12	solubility	solubility	NOUN
admet-2338	154	13	in	in	ADP
admet-2338	154	14	water	water	NOUN
admet-2338	154	15	(	(	PUNCT
admet-2338	154	16	0.0288	0.0288	NUM
admet-2338	154	17	±	±	NUM
admet-2338	154	18	0.0017	0.0017	NUM
admet-2338	154	19	mg	mg	PROPN
admet-2338	154	20	/	/	SYM
admet-2338	154	21	ml	ml	NOUN
admet-2338	154	22	admet	admet	PROPN
admet-2338	154	23	&	&	CCONJ
admet-2338	154	24	dmpk	dmpk	PROPN
admet-2338	154	25	12(4	12(4	PROPN
admet-2338	154	26	)	)	PUNCT
admet-2338	154	27	(	(	PUNCT
admet-2338	154	28	2024	2024	NUM
admet-2338	154	29	)	)	PUNCT
admet-2338	154	30	687	687	NUM
admet-2338	154	31	-	-	SYM
admet-2338	154	32	702	702	NUM
admet-2338	154	33	neusilin	neusilin	PROPN
admet-2338	154	34	us2	us2	PROPN
admet-2338	154	35	based	base	VERB
admet-2338	154	36	surface	surface	NOUN
admet-2338	154	37	solid	solid	ADJ
admet-2338	154	38	dispersion	dispersion	NOUN
admet-2338	154	39	of	of	ADP
admet-2338	154	40	sorafenib	sorafenib	NOUN
admet-2338	154	41	tosylate	tosylate	VERB
admet-2338	154	42	doi	doi	NOUN
admet-2338	154	43	:	:	PUNCT
admet-2338	154	44	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	NOUN
admet-2338	154	45	693	693	NUM
admet-2338	154	46	and	and	CCONJ
admet-2338	154	47	the	the	DET
admet-2338	154	48	highest	high	ADJ
admet-2338	154	49	solubility	solubility	NOUN
admet-2338	154	50	was	be	AUX
admet-2338	154	51	observed	observe	VERB
admet-2338	154	52	in	in	ADP
admet-2338	154	53	dmso	dmso	NOUN
admet-2338	154	54	(	(	PUNCT
admet-2338	154	55	221.79	221.79	NUM
admet-2338	154	56	±	±	NUM
admet-2338	154	57	45.26	45.26	NUM
admet-2338	154	58	mg	mg	PROPN
admet-2338	154	59	/	/	SYM
admet-2338	154	60	ml	ml	NOUN
admet-2338	154	61	)	)	PUNCT
admet-2338	154	62	.	.	PUNCT
admet-2338	155	1	[	[	X
admet-2338	155	2	22,23	22,23	NOUN
admet-2338	155	3	]	]	PUNCT
admet-2338	155	4	.	.	PUNCT
admet-2338	156	1	the	the	DET
admet-2338	156	2	solubility	solubility	NOUN
admet-2338	156	3	order	order	NOUN
admet-2338	156	4	was	be	AUX
admet-2338	156	5	dmso	dmso	NOUN
admet-2338	156	6	>	>	X
admet-2338	156	7	ethanol	ethanol	NOUN
admet-2338	156	8	>	>	X
admet-2338	156	9	methanol	methanol	NOUN
admet-2338	156	10	>	>	X
admet-2338	156	11	0.1	0.1	NUM
admet-2338	156	12	m	m	NOUN
admet-2338	156	13	hcl	hcl	PROPN
admet-2338	156	14	>	>	X
admet-2338	156	15	acetate	acetate	PROPN
admet-2338	156	16	buffer	buffer	NOUN
admet-2338	156	17	ph	ph	VERB
admet-2338	156	18	4.4	4.4	NUM
admet-2338	156	19	>	>	X
admet-2338	156	20	phosphate	phosphate	ADJ
admet-2338	156	21	buffer	buffer	NOUN
admet-2338	156	22	ph	ph	VERB
admet-2338	156	23	6.8	6.8	NUM
admet-2338	156	24	>	>	X
admet-2338	156	25	water	water	NOUN
admet-2338	156	26	,	,	PUNCT
admet-2338	156	27	respectively	respectively	ADV
admet-2338	156	28	.	.	PUNCT
admet-2338	157	1	further	far	ADV
admet-2338	157	2	,	,	PUNCT
admet-2338	157	3	the	the	DET
admet-2338	157	4	sfn	sfn	NOUN
admet-2338	157	5	showed	show	VERB
admet-2338	157	6	insufficient	insufficient	ADJ
admet-2338	157	7	solubility	solubility	NOUN
admet-2338	157	8	in	in	ADP
admet-2338	157	9	common	common	ADJ
admet-2338	157	10	organic	organic	ADJ
admet-2338	157	11	solvents	solvent	NOUN
admet-2338	157	12	such	such	ADJ
admet-2338	157	13	as	as	ADP
admet-2338	157	14	methanol	methanol	NOUN
admet-2338	157	15	and	and	CCONJ
admet-2338	157	16	ethanol	ethanol	NOUN
admet-2338	157	17	.	.	PUNCT
admet-2338	158	1	considering	consider	VERB
admet-2338	158	2	the	the	DET
admet-2338	158	3	formulation	formulation	NOUN
admet-2338	158	4	aspect	aspect	NOUN
admet-2338	158	5	,	,	PUNCT
admet-2338	158	6	dmso	dmso	NOUN
admet-2338	158	7	and	and	CCONJ
admet-2338	158	8	was	be	AUX
admet-2338	158	9	selected	select	VERB
admet-2338	158	10	for	for	ADP
admet-2338	158	11	ssd	ssd	NOUN
admet-2338	158	12	preparation	preparation	NOUN
admet-2338	158	13	.	.	PUNCT
admet-2338	159	1	screening	screen	VERB
admet-2338	159	2	of	of	ADP
admet-2338	159	3	adsorbents	adsorbent	NOUN
admet-2338	159	4	the	the	DET
admet-2338	159	5	silica	silica	NOUN
admet-2338	159	6	-	-	PUNCT
admet-2338	159	7	based	base	VERB
admet-2338	159	8	adsorbents	adsorbent	NOUN
admet-2338	159	9	such	such	ADJ
admet-2338	159	10	as	as	ADP
admet-2338	159	11	aerosil	aerosil	NOUN
admet-2338	159	12	200	200	NUM
admet-2338	159	13	,	,	PUNCT
admet-2338	159	14	rxcipients	rxcipient	NOUN
admet-2338	159	15	gl	gl	X
admet-2338	159	16	100	100	NUM
admet-2338	159	17	,	,	PUNCT
admet-2338	159	18	and	and	CCONJ
admet-2338	159	19	nu2	nu2	ADV
admet-2338	159	20	were	be	AUX
admet-2338	159	21	selected	select	VERB
admet-2338	159	22	to	to	PART
admet-2338	159	23	screen	screen	VERB
admet-2338	159	24	the	the	DET
admet-2338	159	25	sfn	sfn	PROPN
admet-2338	159	26	solubility	solubility	NOUN
admet-2338	159	27	enhancements	enhancement	NOUN
admet-2338	159	28	because	because	SCONJ
admet-2338	159	29	of	of	ADP
admet-2338	159	30	their	their	PRON
admet-2338	159	31	advantages	advantage	NOUN
admet-2338	159	32	like	like	ADP
admet-2338	159	33	high	high	ADJ
admet-2338	159	34	surface	surface	NOUN
admet-2338	159	35	area	area	NOUN
admet-2338	159	36	,	,	PUNCT
admet-2338	159	37	non	non	ADJ
admet-2338	159	38	-	-	NOUN
admet-2338	159	39	toxicity	toxicity	NOUN
admet-2338	159	40	,	,	PUNCT
admet-2338	159	41	and	and	CCONJ
admet-2338	159	42	non	non	NOUN
admet-2338	159	43	-	-	NOUN
admet-2338	159	44	biodegradability	biodegradability	NOUN
admet-2338	159	45	[	[	X
admet-2338	159	46	24	24	NUM
admet-2338	159	47	]	]	PUNCT
admet-2338	159	48	.	.	PUNCT
admet-2338	160	1	as	as	SCONJ
admet-2338	160	2	shown	show	VERB
admet-2338	160	3	in	in	ADP
admet-2338	160	4	figure	figure	NOUN
admet-2338	160	5	2b	2b	NOUN
admet-2338	160	6	,	,	PUNCT
admet-2338	160	7	the	the	DET
admet-2338	160	8	nu2	nu2	NOUN
admet-2338	160	9	showed	show	VERB
admet-2338	160	10	the	the	DET
admet-2338	160	11	highest	high	ADJ
admet-2338	160	12	solubility	solubility	NOUN
admet-2338	160	13	of	of	ADP
admet-2338	160	14	sfn	sfn	PROPN
admet-2338	160	15	(	(	PUNCT
admet-2338	160	16	0.1198	0.1198	NUM
admet-2338	160	17	±	±	NUM
admet-2338	160	18	0.014	0.014	NUM
admet-2338	160	19	mg	mg	PROPN
admet-2338	160	20	/	/	SYM
admet-2338	160	21	ml	ml	NOUN
admet-2338	160	22	)	)	PUNCT
admet-2338	160	23	as	as	SCONJ
admet-2338	160	24	compared	compare	VERB
admet-2338	160	25	to	to	ADP
admet-2338	160	26	other	other	ADJ
admet-2338	160	27	adsorbents	adsorbent	NOUN
admet-2338	160	28	,	,	PUNCT
admet-2338	160	29	which	which	PRON
admet-2338	160	30	may	may	AUX
admet-2338	160	31	be	be	AUX
admet-2338	160	32	due	due	ADJ
admet-2338	160	33	to	to	ADP
admet-2338	160	34	its	its	PRON
admet-2338	160	35	surface	surface	NOUN
admet-2338	160	36	features	feature	NOUN
admet-2338	160	37	such	such	ADJ
admet-2338	160	38	as	as	ADP
admet-2338	160	39	silanol	silanol	ADJ
admet-2338	160	40	functional	functional	ADJ
admet-2338	160	41	groups	group	NOUN
admet-2338	160	42	responsible	responsible	ADJ
admet-2338	160	43	for	for	ADP
admet-2338	160	44	the	the	DET
admet-2338	160	45	hydrogen	hydrogen	NOUN
admet-2338	160	46	bond	bond	NOUN
admet-2338	160	47	with	with	ADP
admet-2338	160	48	drug	drug	NOUN
admet-2338	160	49	molecule	molecule	NOUN
admet-2338	160	50	and	and	CCONJ
admet-2338	160	51	leads	lead	VERB
admet-2338	160	52	to	to	ADP
admet-2338	160	53	improved	improve	VERB
admet-2338	160	54	solubility	solubility	NOUN
admet-2338	160	55	.	.	PUNCT
admet-2338	161	1	also	also	ADV
admet-2338	161	2	,	,	PUNCT
admet-2338	161	3	the	the	DET
admet-2338	161	4	nu2	nu2	NOUN
admet-2338	161	5	is	be	AUX
admet-2338	161	6	highly	highly	ADV
admet-2338	161	7	safe	safe	ADJ
admet-2338	161	8	,	,	PUNCT
admet-2338	161	9	and	and	CCONJ
admet-2338	161	10	no	no	DET
admet-2338	161	11	adverse	adverse	ADJ
admet-2338	161	12	reactions	reaction	NOUN
admet-2338	161	13	were	be	AUX
admet-2338	161	14	reported	report	VERB
admet-2338	161	15	in	in	ADP
admet-2338	161	16	the	the	DET
admet-2338	161	17	us	us	PROPN
admet-2338	161	18	pharmacopoeia	pharmacopoeia	NOUN
admet-2338	161	19	,	,	PUNCT
admet-2338	161	20	national	national	ADJ
admet-2338	161	21	formulary	formulary	NOUN
admet-2338	161	22	,	,	PUNCT
admet-2338	161	23	and	and	CCONJ
admet-2338	162	1	japanese	japanese	ADJ
admet-2338	162	2	pharmaceutical	pharmaceutical	ADJ
admet-2338	162	3	codex	codex	NOUN
admet-2338	162	4	[	[	X
admet-2338	162	5	18,25	18,25	NUM
admet-2338	162	6	]	]	PUNCT
admet-2338	162	7	.	.	PUNCT
admet-2338	163	1	considering	consider	VERB
admet-2338	163	2	the	the	DET
admet-2338	163	3	formulation	formulation	NOUN
admet-2338	163	4	and	and	CCONJ
admet-2338	163	5	solubility	solubility	NOUN
admet-2338	163	6	aspects	aspect	NOUN
admet-2338	163	7	,	,	PUNCT
admet-2338	163	8	the	the	DET
admet-2338	163	9	nu2	nu2	NOUN
admet-2338	163	10	was	be	AUX
admet-2338	163	11	selected	select	VERB
admet-2338	163	12	for	for	ADP
admet-2338	163	13	ssd	ssd	NOUN
admet-2338	163	14	preparation	preparation	NOUN
admet-2338	163	15	.	.	PUNCT
admet-2338	164	1	screening	screen	VERB
admet-2338	164	2	of	of	ADP
admet-2338	164	3	surfactant	surfactant	ADJ
admet-2338	164	4	surfactants	surfactant	NOUN
admet-2338	164	5	are	be	AUX
admet-2338	164	6	chemical	chemical	ADJ
admet-2338	164	7	compounds	compound	NOUN
admet-2338	164	8	that	that	PRON
admet-2338	164	9	reduce	reduce	VERB
admet-2338	164	10	surface	surface	NOUN
admet-2338	164	11	tension	tension	NOUN
admet-2338	164	12	or	or	CCONJ
admet-2338	164	13	increase	increase	VERB
admet-2338	164	14	surface	surface	NOUN
admet-2338	164	15	free	free	ADJ
admet-2338	164	16	energy	energy	NOUN
admet-2338	164	17	.	.	PUNCT
admet-2338	165	1	besides	besides	SCONJ
admet-2338	165	2	that	that	PRON
admet-2338	165	3	,	,	PUNCT
admet-2338	165	4	surfactants	surfactant	NOUN
admet-2338	165	5	have	have	AUX
admet-2338	165	6	been	be	AUX
admet-2338	165	7	widely	widely	ADV
admet-2338	165	8	used	use	VERB
admet-2338	165	9	as	as	ADP
admet-2338	165	10	wetting	wet	VERB
admet-2338	165	11	and	and	CCONJ
admet-2338	165	12	solubilizing	solubilize	VERB
admet-2338	165	13	agents	agent	NOUN
admet-2338	165	14	due	due	ADP
admet-2338	165	15	to	to	ADP
admet-2338	165	16	their	their	PRON
admet-2338	165	17	ability	ability	NOUN
admet-2338	165	18	to	to	PART
admet-2338	165	19	alter	alter	VERB
admet-2338	165	20	physical	physical	ADJ
admet-2338	165	21	properties	property	NOUN
admet-2338	165	22	such	such	ADJ
admet-2338	165	23	as	as	ADP
admet-2338	165	24	hydrophobicity	hydrophobicity	NOUN
admet-2338	165	25	and	and	CCONJ
admet-2338	165	26	wetting	wet	VERB
admet-2338	165	27	properties	property	NOUN
admet-2338	165	28	.	.	PUNCT
admet-2338	166	1	to	to	PART
admet-2338	166	2	select	select	VERB
admet-2338	166	3	an	an	DET
admet-2338	166	4	appropriate	appropriate	ADJ
admet-2338	166	5	surfactant	surfactant	NOUN
admet-2338	166	6	,	,	PUNCT
admet-2338	166	7	their	their	PRON
admet-2338	166	8	ability	ability	NOUN
admet-2338	166	9	to	to	PART
admet-2338	166	10	dissolve	dissolve	VERB
admet-2338	166	11	sfn	sfn	PROPN
admet-2338	166	12	was	be	AUX
admet-2338	166	13	analysed	analyse	VERB
admet-2338	166	14	in	in	ADP
admet-2338	166	15	1	1	NUM
admet-2338	166	16	%	%	NOUN
admet-2338	166	17	w	w	PROPN
admet-2338	166	18	/	/	SYM
admet-2338	166	19	v	v	NOUN
admet-2338	166	20	solution	solution	NOUN
admet-2338	166	21	of	of	ADP
admet-2338	166	22	poloxamer	poloxamer	PROPN
admet-2338	166	23	407	407	NUM
admet-2338	166	24	,	,	PUNCT
admet-2338	166	25	poloxamer	poloxamer	NOUN
admet-2338	166	26	188	188	NUM
admet-2338	166	27	,	,	PUNCT
admet-2338	166	28	gelucire	gelucire	VERB
admet-2338	166	29	50/13	50/13	NUM
admet-2338	166	30	,	,	PUNCT
admet-2338	166	31	sds	sds	NOUN
admet-2338	166	32	,	,	PUNCT
admet-2338	166	33	transcutol	transcutol	ADJ
admet-2338	166	34	p	p	NOUN
admet-2338	166	35	and	and	CCONJ
admet-2338	166	36	labrasol	labrasol	ADJ
admet-2338	166	37	.	.	PUNCT
admet-2338	167	1	as	as	SCONJ
admet-2338	167	2	shown	show	VERB
admet-2338	167	3	in	in	ADP
admet-2338	167	4	figure	figure	NOUN
admet-2338	167	5	2c	2c	NOUN
admet-2338	167	6	,	,	PUNCT
admet-2338	167	7	the	the	DET
admet-2338	167	8	sds	sds	NOUN
admet-2338	167	9	showed	show	VERB
admet-2338	167	10	maximum	maximum	ADJ
admet-2338	167	11	solubility	solubility	NOUN
admet-2338	167	12	(	(	PUNCT
admet-2338	167	13	1.7027	1.7027	NUM
admet-2338	167	14	±	±	NUM
admet-2338	167	15	0.1186	0.1186	NUM
admet-2338	167	16	mg	mg	PROPN
admet-2338	167	17	/	/	SYM
admet-2338	167	18	ml	ml	NOUN
admet-2338	167	19	)	)	PUNCT
admet-2338	167	20	of	of	ADP
admet-2338	167	21	sfn	sfn	PROPN
admet-2338	167	22	compared	compare	VERB
admet-2338	167	23	to	to	ADP
admet-2338	167	24	others	other	NOUN
admet-2338	167	25	.	.	PUNCT
admet-2338	168	1	the	the	DET
admet-2338	168	2	improved	improve	VERB
admet-2338	168	3	solubility	solubility	NOUN
admet-2338	168	4	is	be	AUX
admet-2338	168	5	attributed	attribute	VERB
admet-2338	168	6	to	to	ADP
admet-2338	168	7	its	its	PRON
admet-2338	168	8	higher	high	ADJ
admet-2338	168	9	hydrophilic	hydrophilic	ADJ
admet-2338	168	10	lipophilic	lipophilic	ADJ
admet-2338	168	11	balance	balance	NOUN
admet-2338	168	12	(	(	PUNCT
admet-2338	168	13	hlb	hlb	PROPN
admet-2338	168	14	)	)	PUNCT
admet-2338	168	15	value	value	NOUN
admet-2338	168	16	(	(	PUNCT
admet-2338	168	17	40	40	NUM
admet-2338	168	18	)	)	PUNCT
admet-2338	168	19	,	,	PUNCT
admet-2338	168	20	micellar	micellar	ADJ
admet-2338	168	21	solubilization	solubilization	NOUN
admet-2338	168	22	,	,	PUNCT
admet-2338	168	23	wetting	wet	VERB
admet-2338	168	24	of	of	ADP
admet-2338	168	25	the	the	DET
admet-2338	168	26	drug	drug	NOUN
admet-2338	168	27	particles	particle	NOUN
admet-2338	168	28	and	and	CCONJ
admet-2338	168	29	decreasing	decrease	VERB
admet-2338	168	30	the	the	DET
admet-2338	168	31	surface	surface	NOUN
admet-2338	168	32	tension	tension	NOUN
admet-2338	168	33	[	[	X
admet-2338	168	34	26	26	NUM
admet-2338	168	35	-	-	SYM
admet-2338	168	36	29	29	NUM
admet-2338	168	37	]	]	PUNCT
admet-2338	168	38	.	.	PUNCT
admet-2338	169	1	in	in	ADP
admet-2338	169	2	this	this	DET
admet-2338	169	3	study	study	NOUN
admet-2338	169	4	,	,	PUNCT
admet-2338	169	5	the	the	DET
admet-2338	169	6	sds	sds	PROPN
admet-2338	169	7	surfactant	surfactant	NOUN
admet-2338	169	8	was	be	AUX
admet-2338	169	9	selected	select	VERB
admet-2338	169	10	to	to	PART
admet-2338	169	11	prepare	prepare	VERB
admet-2338	169	12	ssd	ssd	NOUN
admet-2338	169	13	of	of	ADP
admet-2338	169	14	sfn	sfn	PROPN
admet-2338	169	15	.	.	PUNCT
admet-2338	170	1	figure	figure	NOUN
admet-2338	170	2	2	2	NUM
admet-2338	170	3	.	.	PUNCT
admet-2338	170	4	sfn	sfn	PROPN
admet-2338	170	5	solubility	solubility	NOUN
admet-2338	170	6	in	in	ADP
admet-2338	170	7	different	different	ADJ
admet-2338	170	8	(	(	PUNCT
admet-2338	170	9	a	a	NOUN
admet-2338	170	10	)	)	PUNCT
admet-2338	170	11	solvents	solvent	NOUN
admet-2338	170	12	,	,	PUNCT
admet-2338	170	13	(	(	PUNCT
admet-2338	170	14	b	b	X
admet-2338	170	15	)	)	PUNCT
admet-2338	170	16	adsorbents	adsorbent	NOUN
admet-2338	170	17	and	and	CCONJ
admet-2338	170	18	(	(	PUNCT
admet-2338	170	19	c	c	NOUN
admet-2338	170	20	)	)	PUNCT
admet-2338	170	21	surfactants	surfactant	NOUN
admet-2338	170	22	preparation	preparation	NOUN
admet-2338	170	23	and	and	CCONJ
admet-2338	170	24	optimisation	optimisation	NOUN
admet-2338	170	25	sfn	sfn	PROPN
admet-2338	170	26	-	-	PUNCT
admet-2338	170	27	ssd	ssd	NOUN
admet-2338	170	28	the	the	DET
admet-2338	170	29	sfn	sfn	PROPN
admet-2338	170	30	-	-	PUNCT
admet-2338	170	31	ssd	ssd	NOUN
admet-2338	170	32	was	be	AUX
admet-2338	170	33	prepared	prepare	VERB
admet-2338	170	34	using	use	VERB
admet-2338	170	35	a	a	DET
admet-2338	170	36	solvent	solvent	ADJ
admet-2338	170	37	evaporation	evaporation	NOUN
admet-2338	170	38	technique	technique	NOUN
admet-2338	170	39	and	and	CCONJ
admet-2338	170	40	optimized	optimize	VERB
admet-2338	170	41	for	for	ADP
admet-2338	170	42	the	the	DET
admet-2338	170	43	concentration	concentration	NOUN
admet-2338	170	44	of	of	ADP
admet-2338	170	45	adsorbent	adsorbent	NOUN
admet-2338	170	46	and	and	CCONJ
admet-2338	170	47	surfactant	surfactant	NOUN
admet-2338	170	48	by	by	ADP
admet-2338	170	49	adopting	adopt	VERB
admet-2338	170	50	32	32	NUM
admet-2338	170	51	factorial	factorial	ADJ
admet-2338	170	52	design	design	NOUN
admet-2338	170	53	using	use	VERB
admet-2338	170	54	design	design	NOUN
admet-2338	170	55	-	-	PUNCT
admet-2338	170	56	expert	expert	NOUN
admet-2338	170	57	®	®	NOUN
admet-2338	170	58	software	software	NOUN
admet-2338	170	59	version	version	NOUN
admet-2338	170	60	11	11	NUM
admet-2338	170	61	,	,	PUNCT
admet-2338	170	62	stat	stat	NOUN
admet-2338	170	63	-	-	PUNCT
admet-2338	170	64	ease	ease	NOUN
admet-2338	170	65	,	,	PUNCT
admet-2338	170	66	usa	usa	PROPN
admet-2338	170	67	.	.	PROPN
admet-2338	171	1	a	a	DET
admet-2338	171	2	total	total	NOUN
admet-2338	171	3	of	of	ADP
admet-2338	171	4	nine	nine	NUM
admet-2338	171	5	batches	batch	NOUN
admet-2338	171	6	were	be	AUX
admet-2338	171	7	prepared	prepare	VERB
admet-2338	171	8	in	in	ADP
admet-2338	171	9	accordance	accordance	NOUN
admet-2338	171	10	with	with	ADP
admet-2338	171	11	the	the	DET
admet-2338	171	12	factorial	factorial	ADJ
admet-2338	171	13	design	design	NOUN
admet-2338	171	14	.	.	PUNCT
admet-2338	172	1	the	the	DET
admet-2338	172	2	multiple	multiple	ADJ
admet-2338	172	3	regression	regression	NOUN
admet-2338	172	4	analysis	analysis	NOUN
admet-2338	172	5	for	for	ADP
admet-2338	172	6	the	the	DET
admet-2338	172	7	solubility	solubility	NOUN
admet-2338	172	8	of	of	ADP
admet-2338	172	9	factorial	factorial	NOUN
admet-2338	172	10	batches	batch	NOUN
admet-2338	172	11	revealed	reveal	VERB
admet-2338	172	12	a	a	DET
admet-2338	172	13	fair	fair	ADJ
admet-2338	172	14	fit	fit	NOUN
admet-2338	172	15	(	(	PUNCT
admet-2338	172	16	r2	r2	NOUN
admet-2338	172	17	=	=	NOUN
admet-2338	172	18	0.460	0.460	NUM
admet-2338	172	19	)	)	PUNCT
admet-2338	172	20	.	.	PUNCT
admet-2338	173	1	the	the	DET
admet-2338	173	2	positive	positive	ADJ
admet-2338	173	3	coefficient	coefficient	NOUN
admet-2338	173	4	for	for	ADP
admet-2338	173	5	both	both	CCONJ
admet-2338	173	6	independent	independent	ADJ
admet-2338	173	7	variables	variable	NOUN
admet-2338	173	8	influencing	influence	VERB
admet-2338	173	9	the	the	DET
admet-2338	173	10	solubility	solubility	NOUN
admet-2338	173	11	of	of	ADP
admet-2338	173	12	the	the	DET
admet-2338	173	13	sfn	sfn	PROPN
admet-2338	173	14	was	be	AUX
admet-2338	173	15	given	give	VERB
admet-2338	173	16	by	by	ADP
admet-2338	173	17	equation	equation	NOUN
admet-2338	173	18	(	(	PUNCT
admet-2338	173	19	2	2	NUM
admet-2338	173	20	):	):	PUNCT
admet-2338	173	21	y1=	y1=	NOUN
admet-2338	173	22	0.144389	0.144389	NUM
admet-2338	173	23	+	+	CCONJ
admet-2338	173	24	0.007733x1	0.007733x1	NUM
admet-2338	173	25	+	+	SYM
admet-2338	173	26	0.001737x2	0.001737x2	NUM
admet-2338	173	27	(	(	PUNCT
admet-2338	173	28	2	2	NUM
admet-2338	173	29	)	)	PUNCT
admet-2338	173	30	it	it	PRON
admet-2338	173	31	was	be	AUX
admet-2338	173	32	observed	observe	VERB
admet-2338	173	33	that	that	SCONJ
admet-2338	173	34	the	the	DET
admet-2338	173	35	predicted	predict	VERB
admet-2338	173	36	r²	r²	NOUN
admet-2338	173	37	of	of	ADP
admet-2338	173	38	0.5846	0.5846	NUM
admet-2338	173	39	is	be	AUX
admet-2338	173	40	in	in	ADP
admet-2338	173	41	reasonable	reasonable	ADJ
admet-2338	173	42	agreement	agreement	NOUN
admet-2338	173	43	with	with	ADP
admet-2338	173	44	the	the	DET
admet-2338	173	45	adjusted	adjust	VERB
admet-2338	173	46	r²	r²	NOUN
admet-2338	173	47	of	of	ADP
admet-2338	173	48	0.7309	0.7309	NUM
admet-2338	173	49	.	.	PUNCT
admet-2338	174	1	further	far	ADV
admet-2338	174	2	,	,	PUNCT
admet-2338	174	3	the	the	DET
admet-2338	174	4	p	p	NOUN
admet-2338	174	5	-	-	PUNCT
admet-2338	174	6	value	value	NOUN
admet-2338	174	7	and	and	CCONJ
admet-2338	174	8	the	the	DET
admet-2338	174	9	model	model	NOUN
admet-2338	174	10	f	f	NOUN
admet-2338	174	11	-	-	PUNCT
admet-2338	174	12	value	value	NOUN
admet-2338	174	13	less	less	ADJ
admet-2338	174	14	than	than	ADP
admet-2338	174	15	0.0500	0.0500	NUM
admet-2338	174	16	and	and	CCONJ
admet-2338	174	17	11.86	11.86	NUM
admet-2338	174	18	implies	imply	VERB
admet-2338	174	19	the	the	DET
admet-2338	174	20	model	model	NOUN
admet-2338	174	21	is	be	AUX
admet-2338	174	22	significant	significant	ADJ
admet-2338	174	23	.	.	PUNCT
admet-2338	175	1	moreover	moreover	ADV
admet-2338	175	2	,	,	PUNCT
admet-2338	175	3	all	all	DET
admet-2338	175	4	batches	batch	NOUN
admet-2338	175	5	were	be	AUX
admet-2338	175	6	subjected	subject	VERB
admet-2338	175	7	to	to	ADP
admet-2338	175	8	solubility	solubility	NOUN
admet-2338	175	9	analysis	analysis	NOUN
admet-2338	175	10	and	and	CCONJ
admet-2338	175	11	results	result	NOUN
admet-2338	175	12	are	be	AUX
admet-2338	175	13	shown	show	VERB
admet-2338	175	14	in	in	ADP
admet-2338	175	15	table	table	NOUN
admet-2338	175	16	2	2	NUM
admet-2338	175	17	and	and	CCONJ
admet-2338	175	18	the	the	DET
admet-2338	175	19	surface	surface	NOUN
admet-2338	175	20	response	response	NOUN
admet-2338	175	21	3d	3d	PROPN
admet-2338	175	22	plot	plot	NOUN
admet-2338	175	23	is	be	AUX
admet-2338	175	24	depicted	depict	VERB
admet-2338	175	25	in	in	ADP
admet-2338	175	26	figure	figure	NOUN
admet-2338	175	27	3	3	NUM
admet-2338	176	1	.	.	PUNCT
admet-2338	176	2	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	PROPN
admet-2338	176	3	b.	b.	PROPN
admet-2338	176	4	kumar	kumar	PROPN
admet-2338	176	5	panda	panda	PROPN
admet-2338	176	6	et	et	PROPN
admet-2338	176	7	al	al	PROPN
admet-2338	176	8	.	.	PROPN
admet-2338	176	9	admet	admet	PROPN
admet-2338	176	10	&	&	CCONJ
admet-2338	176	11	dmpk	dmpk	PROPN
admet-2338	176	12	12(4	12(4	PROPN
admet-2338	176	13	)	)	PUNCT
admet-2338	176	14	(	(	PUNCT
admet-2338	176	15	2024	2024	NUM
admet-2338	176	16	)	)	PUNCT
admet-2338	176	17	687	687	NUM
admet-2338	176	18	-	-	SYM
admet-2338	176	19	702	702	NUM
admet-2338	176	20	694	694	NUM
admet-2338	176	21	table	table	NOUN
admet-2338	176	22	3	3	NUM
admet-2338	176	23	.	.	PUNCT
admet-2338	176	24	composition	composition	NOUN
admet-2338	176	25	of	of	ADP
admet-2338	176	26	the	the	DET
admet-2338	176	27	sfn	sfn	PROPN
admet-2338	176	28	-	-	PUNCT
admet-2338	176	29	ssd	ssd	NOUN
admet-2338	176	30	and	and	CCONJ
admet-2338	176	31	pure	pure	ADJ
admet-2338	176	32	sfn	sfn	PROPN
admet-2338	176	33	tablet	tablet	NOUN
admet-2338	176	34	ingredients	ingredient	NOUN
admet-2338	176	35	amount	amount	NOUN
admet-2338	176	36	,	,	PUNCT
admet-2338	176	37	mg	mg	PROPN
admet-2338	176	38	sfn	sfn	PROPN
admet-2338	176	39	-	-	PUNCT
admet-2338	176	40	ssd	ssd	NOUN
admet-2338	176	41	tablet	tablet	NOUN
admet-2338	176	42	pure	pure	PROPN
admet-2338	176	43	sfn	sfn	PROPN
admet-2338	176	44	tablet	tablet	PROPN
admet-2338	176	45	sfn	sfn	PROPN
admet-2338	176	46	-	-	PUNCT
admet-2338	176	47	ssd	ssd	NOUN
admet-2338	176	48	456.5	456.5	NUM
admet-2338	176	49	(	(	PUNCT
admet-2338	176	50	equivalent	equivalent	ADJ
admet-2338	176	51	to	to	ADP
admet-2338	176	52	100	100	NUM
admet-2338	176	53	mg	mg	PROPN
admet-2338	176	54	sfn	sfn	PROPN
admet-2338	176	55	)	)	PUNCT
admet-2338	176	56	100.0	100.0	NUM
admet-2338	176	57	(	(	PUNCT
admet-2338	176	58	sfn	sfn	PROPN
admet-2338	176	59	)	)	PUNCT
admet-2338	176	60	croscarmellose	croscarmellose	ADJ
admet-2338	176	61	sodium	sodium	NOUN
admet-2338	176	62	20.0	20.0	NUM
admet-2338	176	63	20.0	20.0	NUM
admet-2338	176	64	mcc	mcc	NOUN
admet-2338	176	65	0.0	0.0	NUM
admet-2338	176	66	356.5	356.5	NUM
admet-2338	176	67	pvp	pvp	NOUN
admet-2338	176	68	k30	k30	NOUN
admet-2338	176	69	10.0	10.0	NUM
admet-2338	176	70	10.0	10.0	NUM
admet-2338	176	71	magnesium	magnesium	NOUN
admet-2338	176	72	stearate	stearate	NOUN
admet-2338	176	73	5.0	5.0	NUM
admet-2338	176	74	5.0	5.0	NUM
admet-2338	176	75	talc	talc	NOUN
admet-2338	176	76	5.0	5.0	NUM
admet-2338	176	77	5.0	5.0	NUM
admet-2338	176	78	total	total	ADJ
admet-2338	176	79	weight	weight	NOUN
admet-2338	176	80	506.5	506.5	NUM
admet-2338	176	81	506.5	506.5	NUM
admet-2338	176	82	all	all	DET
admet-2338	176	83	the	the	DET
admet-2338	176	84	determinations	determination	NOUN
admet-2338	176	85	were	be	AUX
admet-2338	176	86	performed	perform	VERB
admet-2338	176	87	in	in	ADP
admet-2338	176	88	triplicate	triplicate	NOUN
admet-2338	176	89	x1	x1	PROPN
admet-2338	176	90	=	=	PUNCT
admet-2338	176	91	a	a	PROPN
admet-2338	177	1	and	and	CCONJ
admet-2338	177	2	x2	x2	NOUN
admet-2338	178	1	=	=	SYM
admet-2338	178	2	b	b	X
admet-2338	178	3	figure	figure	NOUN
admet-2338	178	4	3	3	NUM
admet-2338	178	5	.	.	PUNCT
admet-2338	178	6	response	response	NOUN
admet-2338	178	7	surface	surface	NOUN
admet-2338	178	8	plot	plot	NOUN
admet-2338	178	9	showing	show	VERB
admet-2338	178	10	effect	effect	NOUN
admet-2338	178	11	of	of	ADP
admet-2338	178	12	factorial	factorial	ADJ
admet-2338	178	13	variables	variable	NOUN
admet-2338	178	14	on	on	ADP
admet-2338	178	15	sfn	sfn	PROPN
admet-2338	178	16	solubility	solubility	NOUN
admet-2338	178	17	the	the	DET
admet-2338	178	18	3d	3d	NUM
admet-2338	178	19	surface	surface	NOUN
admet-2338	178	20	response	response	NOUN
admet-2338	178	21	plot	plot	NOUN
admet-2338	178	22	of	of	ADP
admet-2338	178	23	the	the	DET
admet-2338	178	24	interaction	interaction	NOUN
admet-2338	178	25	between	between	ADP
admet-2338	178	26	the	the	DET
admet-2338	178	27	nu2	nu2	NOUN
admet-2338	178	28	and	and	CCONJ
admet-2338	178	29	sds	sds	PROPN
admet-2338	178	30	was	be	AUX
admet-2338	178	31	plotted	plot	VERB
admet-2338	178	32	with	with	ADP
admet-2338	178	33	the	the	DET
admet-2338	178	34	response	response	NOUN
admet-2338	178	35	of	of	ADP
admet-2338	178	36	sfn	sfn	PROPN
admet-2338	178	37	solubility	solubility	NOUN
admet-2338	178	38	.	.	PUNCT
admet-2338	179	1	the	the	DET
admet-2338	179	2	surface	surface	NOUN
admet-2338	179	3	plot	plot	NOUN
admet-2338	179	4	showed	show	VERB
admet-2338	179	5	that	that	SCONJ
admet-2338	179	6	the	the	DET
admet-2338	179	7	adsorbent	adsorbent	NOUN
admet-2338	179	8	had	have	VERB
admet-2338	179	9	a	a	DET
admet-2338	179	10	significant	significant	ADJ
admet-2338	179	11	(	(	PUNCT
admet-2338	179	12	p	p	X
admet-2338	179	13	<	<	X
admet-2338	179	14	0.05	0.05	NUM
admet-2338	179	15	)	)	PUNCT
admet-2338	179	16	effect	effect	NOUN
admet-2338	179	17	on	on	ADP
admet-2338	179	18	the	the	DET
admet-2338	179	19	solubility	solubility	NOUN
admet-2338	179	20	until	until	ADP
admet-2338	179	21	the	the	DET
admet-2338	179	22	concentration	concentration	NOUN
admet-2338	179	23	of	of	ADP
admet-2338	179	24	150	150	NUM
admet-2338	179	25	mg	mg	NUM
admet-2338	179	26	;	;	PUNCT
admet-2338	179	27	after	after	ADP
admet-2338	179	28	that	that	PRON
admet-2338	179	29	,	,	PUNCT
admet-2338	179	30	there	there	PRON
admet-2338	179	31	were	be	VERB
admet-2338	179	32	no	no	DET
admet-2338	179	33	significant	significant	ADJ
admet-2338	179	34	increments	increment	NOUN
admet-2338	179	35	in	in	ADP
admet-2338	179	36	sfn	sfn	PROPN
admet-2338	179	37	solubility	solubility	NOUN
admet-2338	179	38	,	,	PUNCT
admet-2338	179	39	which	which	PRON
admet-2338	179	40	may	may	AUX
admet-2338	179	41	be	be	AUX
admet-2338	179	42	due	due	ADJ
admet-2338	179	43	to	to	ADP
admet-2338	179	44	the	the	DET
admet-2338	179	45	adsorption	adsorption	NOUN
admet-2338	179	46	sfn	sfn	NOUN
admet-2338	179	47	on	on	ADP
admet-2338	179	48	nu2	nu2	PROPN
admet-2338	179	49	.	.	PUNCT
admet-2338	180	1	therefore	therefore	ADV
admet-2338	180	2	,	,	PUNCT
admet-2338	180	3	150	150	NUM
admet-2338	180	4	mg	mg	NOUN
admet-2338	180	5	of	of	ADP
admet-2338	180	6	nu2	nu2	NOUN
admet-2338	180	7	is	be	AUX
admet-2338	180	8	taken	take	VERB
admet-2338	180	9	as	as	ADP
admet-2338	180	10	an	an	DET
admet-2338	180	11	optimised	optimise	VERB
admet-2338	180	12	concentration	concentration	NOUN
admet-2338	180	13	.	.	PUNCT
admet-2338	181	1	nu2	nu2	PROPN
admet-2338	181	2	shows	show	VERB
admet-2338	181	3	significant	significant	ADJ
admet-2338	181	4	variation	variation	NOUN
admet-2338	181	5	in	in	ADP
admet-2338	181	6	effect	effect	NOUN
admet-2338	181	7	with	with	ADP
admet-2338	181	8	the	the	DET
admet-2338	181	9	surfactant	surfactant	ADJ
admet-2338	181	10	concentration	concentration	NOUN
admet-2338	181	11	.	.	PUNCT
admet-2338	182	1	the	the	DET
admet-2338	182	2	batches	batch	NOUN
admet-2338	182	3	with	with	ADP
admet-2338	182	4	higher	high	ADJ
admet-2338	182	5	concentration	concentration	NOUN
admet-2338	182	6	of	of	ADP
admet-2338	182	7	the	the	DET
admet-2338	182	8	surfactant	surfactant	NOUN
admet-2338	182	9	(	(	PUNCT
admet-2338	182	10	25	25	NUM
admet-2338	182	11	mg	mg	NOUN
admet-2338	182	12	)	)	PUNCT
admet-2338	182	13	,	,	PUNCT
admet-2338	182	14	the	the	DET
admet-2338	182	15	adsorbent	adsorbent	NOUN
admet-2338	182	16	shows	show	VERB
admet-2338	182	17	the	the	DET
admet-2338	182	18	highest	high	ADJ
admet-2338	182	19	effect	effect	NOUN
admet-2338	182	20	compared	compare	VERB
admet-2338	182	21	to	to	ADP
admet-2338	182	22	the	the	DET
admet-2338	182	23	batches	batch	NOUN
admet-2338	182	24	with	with	ADP
admet-2338	182	25	lower	low	ADJ
admet-2338	182	26	surfactant	surfactant	ADJ
admet-2338	182	27	concentrations	concentration	NOUN
admet-2338	182	28	(	(	PUNCT
admet-2338	182	29	15	15	NUM
admet-2338	182	30	mg	mg	NUM
admet-2338	182	31	)	)	PUNCT
admet-2338	182	32	.	.	PUNCT
admet-2338	183	1	this	this	PRON
admet-2338	183	2	may	may	AUX
admet-2338	183	3	be	be	AUX
admet-2338	183	4	because	because	SCONJ
admet-2338	183	5	of	of	ADP
admet-2338	183	6	the	the	DET
admet-2338	183	7	insufficient	insufficient	ADJ
admet-2338	183	8	adsorption	adsorption	NOUN
admet-2338	183	9	of	of	ADP
admet-2338	183	10	the	the	DET
admet-2338	183	11	surfactant	surfactant	ADJ
admet-2338	183	12	-	-	PUNCT
admet-2338	183	13	drug	drug	NOUN
admet-2338	183	14	molecule	molecule	NOUN
admet-2338	183	15	on	on	ADP
admet-2338	183	16	nu2	nu2	PROPN
admet-2338	183	17	at	at	ADP
admet-2338	183	18	a	a	DET
admet-2338	183	19	lower	low	ADJ
admet-2338	183	20	concentration	concentration	NOUN
admet-2338	183	21	.	.	PUNCT
admet-2338	184	1	similarly	similarly	ADV
admet-2338	184	2	,	,	PUNCT
admet-2338	184	3	sds	sds	PROPN
admet-2338	184	4	with	with	ADP
admet-2338	184	5	a	a	DET
admet-2338	184	6	larger	large	ADJ
admet-2338	184	7	amount	amount	NOUN
admet-2338	184	8	(	(	PUNCT
admet-2338	184	9	>	>	SYM
admet-2338	184	10	25	25	NUM
admet-2338	184	11	mg	mg	NOUN
admet-2338	184	12	)	)	PUNCT
admet-2338	184	13	does	do	AUX
admet-2338	184	14	n’t	not	PART
admet-2338	184	15	show	show	VERB
admet-2338	184	16	much	much	ADJ
admet-2338	184	17	difference	difference	NOUN
admet-2338	184	18	;	;	PUNCT
admet-2338	184	19	considering	consider	VERB
admet-2338	184	20	the	the	DET
admet-2338	184	21	cost	cost	NOUN
admet-2338	184	22	of	of	ADP
admet-2338	184	23	excipients	excipient	NOUN
admet-2338	184	24	and	and	CCONJ
admet-2338	184	25	formulation	formulation	NOUN
admet-2338	184	26	efficiency	efficiency	NOUN
admet-2338	184	27	,	,	PUNCT
admet-2338	184	28	batch	batch	NOUN
admet-2338	184	29	5	5	NUM
admet-2338	184	30	was	be	AUX
admet-2338	184	31	selected	select	VERB
admet-2338	184	32	as	as	ADP
admet-2338	184	33	an	an	DET
admet-2338	184	34	optimised	optimise	VERB
admet-2338	184	35	batch	batch	NOUN
admet-2338	184	36	and	and	CCONJ
admet-2338	184	37	further	far	ADV
admet-2338	184	38	evaluated	evaluate	VERB
admet-2338	184	39	as	as	SCONJ
admet-2338	184	40	shown	show	VERB
admet-2338	184	41	in	in	ADP
admet-2338	184	42	table	table	NOUN
admet-2338	184	43	3	3	NUM
admet-2338	184	44	.	.	X
admet-2338	184	45	yield	yield	NOUN
admet-2338	184	46	and	and	CCONJ
admet-2338	184	47	drug	drug	NOUN
admet-2338	184	48	content	content	NOUN
admet-2338	184	49	the	the	DET
admet-2338	184	50	dried	dry	VERB
admet-2338	184	51	weight	weight	NOUN
admet-2338	184	52	of	of	ADP
admet-2338	184	53	sfn	sfn	PROPN
admet-2338	184	54	-	-	PUNCT
admet-2338	184	55	ssd	ssd	NOUN
admet-2338	184	56	was	be	AUX
admet-2338	184	57	recorded	record	VERB
admet-2338	184	58	to	to	PART
admet-2338	184	59	determine	determine	VERB
admet-2338	184	60	the	the	DET
admet-2338	184	61	practical	practical	ADJ
admet-2338	184	62	yield	yield	NOUN
admet-2338	184	63	.	.	PUNCT
admet-2338	185	1	the	the	DET
admet-2338	185	2	samples	sample	NOUN
admet-2338	185	3	were	be	AUX
admet-2338	185	4	then	then	ADV
admet-2338	185	5	dissolved	dissolve	VERB
admet-2338	185	6	in	in	ADP
admet-2338	185	7	an	an	DET
admet-2338	185	8	appropriate	appropriate	ADJ
admet-2338	185	9	amount	amount	NOUN
admet-2338	185	10	of	of	ADP
admet-2338	185	11	methanol	methanol	NOUN
admet-2338	185	12	using	use	VERB
admet-2338	185	13	a	a	DET
admet-2338	185	14	cyclomixer	cyclomixer	NOUN
admet-2338	185	15	and	and	CCONJ
admet-2338	185	16	ultrasonicator	ultrasonicator	NOUN
admet-2338	185	17	.	.	PUNCT
admet-2338	186	1	after	after	ADP
admet-2338	186	2	making	make	VERB
admet-2338	186	3	the	the	DET
admet-2338	186	4	necessary	necessary	ADJ
admet-2338	186	5	dilutions	dilution	NOUN
admet-2338	186	6	,	,	PUNCT
admet-2338	186	7	the	the	DET
admet-2338	186	8	sfn	sfn	PROPN
admet-2338	186	9	content	content	NOUN
admet-2338	186	10	was	be	AUX
admet-2338	186	11	measured	measure	VERB
admet-2338	186	12	at	at	ADP
admet-2338	186	13	265	265	NUM
admet-2338	186	14	nm	nm	NOUN
admet-2338	186	15	with	with	ADP
admet-2338	186	16	a	a	DET
admet-2338	186	17	spectrophotometer	spectrophotometer	NOUN
admet-2338	186	18	(	(	PUNCT
admet-2338	186	19	uv-530	uv-530	PROPN
admet-2338	186	20	;	;	PUNCT
admet-2338	186	21	jasco	jasco	PROPN
admet-2338	186	22	,	,	PUNCT
admet-2338	186	23	japan	japan	PROPN
admet-2338	186	24	)	)	PUNCT
admet-2338	186	25	.	.	PUNCT
admet-2338	187	1	fourier	fourier	PROPN
admet-2338	187	2	transform	transform	VERB
admet-2338	187	3	infrared	infrared	ADJ
admet-2338	187	4	spectroscopy	spectroscopy	VERB
admet-2338	187	5	the	the	DET
admet-2338	187	6	ftir	ftir	PROPN
admet-2338	187	7	spectra	spectra	NOUN
admet-2338	187	8	of	of	ADP
admet-2338	187	9	pure	pure	ADJ
admet-2338	187	10	sfn	sfn	PROPN
admet-2338	187	11	,	,	PUNCT
admet-2338	187	12	nu2	nu2	INTJ
admet-2338	187	13	,	,	PUNCT
admet-2338	187	14	physical	physical	ADJ
admet-2338	187	15	mixture	mixture	NOUN
admet-2338	187	16	and	and	CCONJ
admet-2338	187	17	sfn	sfn	PROPN
admet-2338	187	18	-	-	PUNCT
admet-2338	187	19	ssd	ssd	NOUN
admet-2338	187	20	are	be	AUX
admet-2338	187	21	shown	show	VERB
admet-2338	187	22	in	in	ADP
admet-2338	187	23	figure	figure	NOUN
admet-2338	187	24	4	4	NUM
admet-2338	187	25	.	.	PUNCT
admet-2338	188	1	the	the	DET
admet-2338	188	2	ft	ft	PROPN
admet-2338	188	3	-	-	PUNCT
admet-2338	188	4	ir	ir	NOUN
admet-2338	188	5	spectrum	spectrum	NOUN
admet-2338	188	6	of	of	ADP
admet-2338	188	7	pure	pure	ADJ
admet-2338	188	8	sfn	sfn	PROPN
admet-2338	188	9	showed	show	VERB
admet-2338	188	10	unique	unique	ADJ
admet-2338	188	11	bands	band	NOUN
admet-2338	188	12	at	at	ADP
admet-2338	188	13	3224.96	3224.96	NUM
admet-2338	188	14	cm-1	cm-1	X
admet-2338	188	15	(	(	PUNCT
admet-2338	188	16	n	n	CCONJ
admet-2338	188	17	-	-	PUNCT
admet-2338	188	18	h	h	NOUN
admet-2338	188	19	stretching	stretch	VERB
admet-2338	188	20	vibration	vibration	NOUN
admet-2338	188	21	of	of	ADP
admet-2338	188	22	the	the	DET
admet-2338	188	23	nh	nh	PROPN
admet-2338	188	24	group	group	NOUN
admet-2338	188	25	)	)	PUNCT
admet-2338	188	26	,	,	PUNCT
admet-2338	188	27	1601.59	1601.59	NUM
admet-2338	188	28	cm-1	cm-1	X
admet-2338	188	29	(	(	PUNCT
admet-2338	188	30	c	c	X
admet-2338	188	31	=	=	NOUN
admet-2338	188	32	o	o	NOUN
admet-2338	188	33	stretching	stretch	VERB
admet-2338	188	34	vibration	vibration	NOUN
admet-2338	188	35	of	of	ADP
admet-2338	188	36	the	the	DET
admet-2338	188	37	amide	amide	NOUN
admet-2338	188	38	group	group	NOUN
admet-2338	188	39	)	)	PUNCT
admet-2338	188	40	and	and	CCONJ
admet-2338	188	41	1182	1182	NUM
admet-2338	188	42	cm-1	cm-1	X
admet-2338	189	1	(	(	PUNCT
admet-2338	189	2	c	c	X
admet-2338	189	3	-	-	PUNCT
admet-2338	189	4	f	f	NOUN
admet-2338	189	5	stretching	stretching	NOUN
admet-2338	189	6	)	)	PUNCT
admet-2338	190	1	[	[	X
admet-2338	190	2	30,31	30,31	NUM
admet-2338	190	3	]	]	PUNCT
admet-2338	190	4	.	.	PUNCT
admet-2338	191	1	in	in	ADP
admet-2338	191	2	the	the	DET
admet-2338	191	3	spectrum	spectrum	NOUN
admet-2338	191	4	of	of	ADP
admet-2338	191	5	the	the	DET
admet-2338	191	6	sfn	sfn	PROPN
admet-2338	191	7	-	-	PUNCT
admet-2338	191	8	ssd	ssd	PROPN
admet-2338	191	9	,	,	PUNCT
admet-2338	191	10	the	the	DET
admet-2338	191	11	sfn	sfn	PROPN
admet-2338	191	12	adsorbed	adsorb	VERB
admet-2338	191	13	at	at	ADP
admet-2338	191	14	nu2	nu2	PROPN
admet-2338	191	15	showed	show	VERB
admet-2338	191	16	weaker	weak	ADJ
admet-2338	191	17	c	c	NOUN
admet-2338	191	18	=	=	NOUN
admet-2338	191	19	o	o	NOUN
admet-2338	191	20	stretching	stretching	NOUN
admet-2338	191	21	of	of	ADP
admet-2338	191	22	the	the	DET
admet-2338	191	23	amide	amide	NOUN
admet-2338	191	24	at	at	ADP
admet-2338	191	25	1602	1602	NUM
admet-2338	191	26	cm1	cm1	NOUN
admet-2338	191	27	due	due	ADP
admet-2338	191	28	to	to	ADP
admet-2338	191	29	interaction	interaction	NOUN
admet-2338	191	30	of	of	ADP
admet-2338	191	31	mg+2	mg+2	NOUN
admet-2338	191	32	and	and	CCONJ
admet-2338	191	33	al+3	al+3	NOUN
admet-2338	191	34	with	with	ADP
admet-2338	191	35	the	the	DET
admet-2338	191	36	carbonyl	carbonyl	NOUN
admet-2338	191	37	group	group	NOUN
admet-2338	191	38	of	of	ADP
admet-2338	191	39	amides	amide	NOUN
admet-2338	191	40	.	.	PUNCT
admet-2338	192	1	transfer	transfer	NOUN
admet-2338	192	2	of	of	ADP
admet-2338	192	3	a	a	DET
admet-2338	192	4	lone	lone	ADJ
admet-2338	192	5	pair	pair	NOUN
admet-2338	192	6	of	of	ADP
admet-2338	192	7	electrons	electron	NOUN
admet-2338	192	8	admet	admet	X
admet-2338	192	9	&	&	CCONJ
admet-2338	192	10	dmpk	dmpk	PROPN
admet-2338	192	11	12(4	12(4	PROPN
admet-2338	192	12	)	)	PUNCT
admet-2338	192	13	(	(	PUNCT
admet-2338	192	14	2024	2024	NUM
admet-2338	192	15	)	)	PUNCT
admet-2338	192	16	687	687	NUM
admet-2338	192	17	-	-	SYM
admet-2338	192	18	702	702	NUM
admet-2338	192	19	neusilin	neusilin	PROPN
admet-2338	192	20	us2	us2	PROPN
admet-2338	192	21	based	base	VERB
admet-2338	192	22	surface	surface	NOUN
admet-2338	192	23	solid	solid	ADJ
admet-2338	192	24	dispersion	dispersion	NOUN
admet-2338	192	25	of	of	ADP
admet-2338	192	26	sorafenib	sorafenib	NOUN
admet-2338	192	27	tosylate	tosylate	VERB
admet-2338	192	28	doi	doi	NOUN
admet-2338	192	29	:	:	PUNCT
admet-2338	192	30	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	NOUN
admet-2338	192	31	695	695	NUM
admet-2338	192	32	to	to	ADP
admet-2338	192	33	the	the	DET
admet-2338	192	34	metal	metal	NOUN
admet-2338	192	35	ions	ion	NOUN
admet-2338	192	36	leads	lead	VERB
admet-2338	192	37	to	to	ADP
admet-2338	192	38	the	the	DET
admet-2338	192	39	conversion	conversion	NOUN
admet-2338	192	40	of	of	ADP
admet-2338	192	41	-c	-c	PROPN
admet-2338	192	42	=	=	PROPN
admet-2338	192	43	oto	oto	PROPN
admet-2338	192	44	-co-	-co-	PROPN
admet-2338	192	45	,	,	PUNCT
admet-2338	192	46	indicating	indicate	VERB
admet-2338	192	47	a	a	DET
admet-2338	192	48	π	π	PROPN
admet-2338	192	49	-	-	PUNCT
admet-2338	192	50	π	π	PROPN
admet-2338	192	51	*	*	NOUN
admet-2338	192	52	transition	transition	NOUN
admet-2338	192	53	.	.	PUNCT
admet-2338	193	1	the	the	DET
admet-2338	193	2	c	c	NOUN
admet-2338	193	3	-	-	PUNCT
admet-2338	193	4	o	o	NOUN
admet-2338	193	5	bond	bond	NOUN
admet-2338	193	6	is	be	AUX
admet-2338	193	7	weaker	weak	ADJ
admet-2338	193	8	compared	compare	VERB
admet-2338	193	9	to	to	ADP
admet-2338	193	10	the	the	DET
admet-2338	193	11	c	c	PROPN
admet-2338	193	12	=	=	PROPN
admet-2338	193	13	o	o	NOUN
admet-2338	193	14	group	group	NOUN
admet-2338	193	15	,	,	PUNCT
admet-2338	193	16	leading	lead	VERB
admet-2338	193	17	to	to	ADP
admet-2338	193	18	the	the	DET
admet-2338	193	19	shifting	shifting	NOUN
admet-2338	193	20	of	of	ADP
admet-2338	193	21	a	a	DET
admet-2338	193	22	peak	peak	NOUN
admet-2338	193	23	.	.	PUNCT
admet-2338	194	1	further	far	ADV
admet-2338	194	2	,	,	PUNCT
admet-2338	194	3	the	the	DET
admet-2338	194	4	carboxylic	carboxylic	ADJ
admet-2338	194	5	group	group	NOUN
admet-2338	194	6	of	of	ADP
admet-2338	194	7	sfn	sfn	PROPN
admet-2338	194	8	is	be	AUX
admet-2338	194	9	bonded	bond	VERB
admet-2338	194	10	with	with	ADP
admet-2338	194	11	the	the	DET
admet-2338	194	12	silanol	silanol	NOUN
admet-2338	194	13	group	group	NOUN
admet-2338	194	14	of	of	ADP
admet-2338	194	15	nu2	nu2	PROPN
admet-2338	194	16	through	through	ADP
admet-2338	194	17	hydrogen	hydrogen	NOUN
admet-2338	194	18	bonding	bonding	NOUN
admet-2338	194	19	indicated	indicate	VERB
admet-2338	194	20	in	in	ADP
admet-2338	194	21	the	the	DET
admet-2338	194	22	form	form	NOUN
admet-2338	194	23	of	of	ADP
admet-2338	194	24	a	a	DET
admet-2338	194	25	broad	broad	ADJ
admet-2338	194	26	peak	peak	NOUN
admet-2338	194	27	between	between	ADP
admet-2338	194	28	3000	3000	NUM
admet-2338	194	29	and	and	CCONJ
admet-2338	194	30	2500	2500	NUM
admet-2338	194	31	cm-1	cm-1	NOUN
admet-2338	194	32	.	.	PUNCT
admet-2338	195	1	thus	thus	ADV
admet-2338	195	2	,	,	PUNCT
admet-2338	195	3	h	h	NOUN
admet-2338	195	4	bonding	bonding	NOUN
admet-2338	195	5	could	could	AUX
admet-2338	195	6	be	be	AUX
admet-2338	195	7	responsible	responsible	ADJ
admet-2338	195	8	for	for	ADP
admet-2338	195	9	the	the	DET
admet-2338	195	10	improvement	improvement	NOUN
admet-2338	195	11	in	in	ADP
admet-2338	195	12	the	the	DET
admet-2338	195	13	solubility	solubility	NOUN
admet-2338	195	14	and	and	CCONJ
admet-2338	195	15	dissolution	dissolution	NOUN
admet-2338	195	16	rate	rate	NOUN
admet-2338	195	17	of	of	ADP
admet-2338	195	18	sfn	sfn	PROPN
admet-2338	196	1	[	[	X
admet-2338	196	2	32,33	32,33	NUM
admet-2338	196	3	]	]	PUNCT
admet-2338	196	4	.	.	PUNCT
admet-2338	197	1	figure	figure	NOUN
admet-2338	197	2	4	4	NUM
admet-2338	197	3	.	.	PUNCT
admet-2338	197	4	ftir	ftir	PROPN
admet-2338	197	5	spectra	spectra	PROPN
admet-2338	197	6	of	of	ADP
admet-2338	197	7	a	a	DET
admet-2338	197	8	sfn	sfn	PROPN
admet-2338	197	9	,	,	PUNCT
admet-2338	197	10	b	b	PROPN
admet-2338	197	11	neusilin	neusilin	PROPN
admet-2338	197	12	us2	us2	PROPN
admet-2338	197	13	,	,	PUNCT
admet-2338	197	14	c	c	PROPN
admet-2338	197	15	physical	physical	ADJ
admet-2338	197	16	mixture	mixture	NOUN
admet-2338	197	17	and	and	CCONJ
admet-2338	197	18	d	d	NOUN
admet-2338	197	19	sfn	sfn	PROPN
admet-2338	197	20	-	-	PUNCT
admet-2338	197	21	ssd	ssd	NOUN
admet-2338	197	22	x	x	NOUN
admet-2338	197	23	-	-	NOUN
admet-2338	197	24	ray	ray	NOUN
admet-2338	197	25	powder	powder	NOUN
admet-2338	197	26	diffraction	diffraction	NOUN
admet-2338	197	27	the	the	DET
admet-2338	197	28	pxrd	pxrd	NOUN
admet-2338	197	29	was	be	AUX
admet-2338	197	30	performed	perform	VERB
admet-2338	197	31	to	to	PART
admet-2338	197	32	confirm	confirm	VERB
admet-2338	197	33	the	the	DET
admet-2338	197	34	crystallinity	crystallinity	NOUN
admet-2338	197	35	of	of	ADP
admet-2338	197	36	sfn	sfn	PROPN
admet-2338	197	37	in	in	ADP
admet-2338	197	38	ssd	ssd	PROPN
admet-2338	197	39	.	.	PUNCT
admet-2338	198	1	the	the	DET
admet-2338	198	2	x	x	ADJ
admet-2338	198	3	-	-	NOUN
admet-2338	198	4	ray	ray	NOUN
admet-2338	198	5	diffraction	diffraction	NOUN
admet-2338	198	6	patterns	pattern	NOUN
admet-2338	198	7	of	of	ADP
admet-2338	198	8	the	the	DET
admet-2338	198	9	pure	pure	ADJ
admet-2338	198	10	sfn	sfn	PROPN
admet-2338	198	11	,	,	PUNCT
admet-2338	198	12	nu2	nu2	INTJ
admet-2338	198	13	,	,	PUNCT
admet-2338	198	14	physical	physical	ADJ
admet-2338	198	15	mixture	mixture	NOUN
admet-2338	198	16	and	and	CCONJ
admet-2338	198	17	sfn	sfn	PROPN
admet-2338	198	18	-	-	PUNCT
admet-2338	198	19	ssd	ssd	NOUN
admet-2338	198	20	are	be	AUX
admet-2338	198	21	shown	show	VERB
admet-2338	198	22	in	in	ADP
admet-2338	198	23	figure	figure	NOUN
admet-2338	198	24	5	5	NUM
admet-2338	198	25	.	.	PUNCT
admet-2338	199	1	2	2	NUM
admet-2338	199	2	/	/	SYM
admet-2338	200	1	°	°	NUM
admet-2338	200	2	figure	figure	NOUN
admet-2338	200	3	5	5	NUM
admet-2338	200	4	.	.	PUNCT
admet-2338	201	1	powder	powder	NOUN
admet-2338	201	2	x	x	PROPN
admet-2338	201	3	-	-	NOUN
admet-2338	201	4	ray	ray	NOUN
admet-2338	201	5	diffraction	diffraction	NOUN
admet-2338	201	6	patterns	pattern	NOUN
admet-2338	201	7	of	of	ADP
admet-2338	201	8	a	a	DET
admet-2338	201	9	sfn	sfn	PROPN
admet-2338	201	10	,	,	PUNCT
admet-2338	201	11	b	b	PROPN
admet-2338	201	12	neusilin	neusilin	PROPN
admet-2338	201	13	us2	us2	PROPN
admet-2338	201	14	,	,	PUNCT
admet-2338	201	15	c	c	PROPN
admet-2338	201	16	physical	physical	ADJ
admet-2338	201	17	mixture	mixture	NOUN
admet-2338	201	18	and	and	CCONJ
admet-2338	201	19	d.	d.	PROPN
admet-2338	201	20	sfn	sfn	PROPN
admet-2338	201	21	-	-	PUNCT
admet-2338	201	22	ssd	ssd	NOUN
admet-2338	201	23	the	the	DET
admet-2338	201	24	pure	pure	ADJ
admet-2338	201	25	sfn	sfn	PROPN
admet-2338	201	26	exhibited	exhibit	VERB
admet-2338	201	27	characteristic	characteristic	ADJ
admet-2338	201	28	pxrd	pxrd	NOUN
admet-2338	201	29	peaks	peak	NOUN
admet-2338	201	30	at	at	ADP
admet-2338	201	31	2	2	NUM
admet-2338	201	32	of	of	ADP
admet-2338	201	33	17.9	17.9	NUM
admet-2338	201	34	,	,	PUNCT
admet-2338	201	35	20.03	20.03	NUM
admet-2338	201	36	,	,	PUNCT
admet-2338	201	37	21.7	21.7	NUM
admet-2338	201	38	and	and	CCONJ
admet-2338	201	39	26.04	26.04	NUM
admet-2338	201	40	°	°	NOUN
admet-2338	201	41	,	,	PUNCT
admet-2338	201	42	indicating	indicate	VERB
admet-2338	201	43	its	its	PRON
admet-2338	201	44	crystalline	crystalline	ADJ
admet-2338	201	45	nature	nature	NOUN
admet-2338	201	46	as	as	SCONJ
admet-2338	201	47	previously	previously	ADV
admet-2338	201	48	reported	report	VERB
admet-2338	201	49	[	[	X
admet-2338	201	50	34	34	NUM
admet-2338	201	51	]	]	PUNCT
admet-2338	201	52	.	.	PUNCT
admet-2338	202	1	in	in	ADP
admet-2338	202	2	the	the	DET
admet-2338	202	3	case	case	NOUN
admet-2338	202	4	of	of	ADP
admet-2338	202	5	the	the	DET
admet-2338	202	6	pxrd	pxrd	NOUN
admet-2338	202	7	patterns	pattern	NOUN
admet-2338	202	8	of	of	ADP
admet-2338	202	9	sfn	sfn	PROPN
admet-2338	202	10	-	-	PUNCT
admet-2338	202	11	ssd	ssd	PROPN
admet-2338	202	12	,	,	PUNCT
admet-2338	202	13	the	the	DET
admet-2338	202	14	intensity	intensity	NOUN
admet-2338	202	15	of	of	ADP
admet-2338	202	16	the	the	DET
admet-2338	202	17	characteristic	characteristic	ADJ
admet-2338	202	18	peaks	peak	NOUN
admet-2338	202	19	shown	show	VERB
admet-2338	202	20	by	by	ADP
admet-2338	202	21	the	the	DET
admet-2338	202	22	pure	pure	ADJ
admet-2338	202	23	sfn	sfn	PROPN
admet-2338	202	24	disappeared	disappear	VERB
admet-2338	202	25	,	,	PUNCT
admet-2338	202	26	indicating	indicate	VERB
admet-2338	202	27	the	the	DET
admet-2338	202	28	complete	complete	ADJ
admet-2338	202	29	molecular	molecular	ADJ
admet-2338	202	30	dispersion	dispersion	NOUN
admet-2338	202	31	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	PROPN
admet-2338	202	32	b.	b.	PROPN
admet-2338	202	33	kumar	kumar	PROPN
admet-2338	202	34	panda	panda	PROPN
admet-2338	202	35	et	et	PROPN
admet-2338	202	36	al	al	PROPN
admet-2338	202	37	.	.	PROPN
admet-2338	202	38	admet	admet	PROPN
admet-2338	202	39	&	&	CCONJ
admet-2338	202	40	dmpk	dmpk	PROPN
admet-2338	202	41	12(4	12(4	PROPN
admet-2338	202	42	)	)	PUNCT
admet-2338	202	43	(	(	PUNCT
admet-2338	202	44	2024	2024	NUM
admet-2338	202	45	)	)	PUNCT
admet-2338	202	46	687	687	NUM
admet-2338	202	47	-	-	SYM
admet-2338	202	48	702	702	NUM
admet-2338	202	49	696	696	NUM
admet-2338	202	50	of	of	ADP
admet-2338	202	51	sfn	sfn	PROPN
admet-2338	202	52	in	in	ADP
admet-2338	202	53	adsorbent	adsorbent	NOUN
admet-2338	202	54	matrices	matrix	NOUN
admet-2338	202	55	as	as	ADP
admet-2338	202	56	an	an	DET
admet-2338	202	57	amorphous	amorphous	ADJ
admet-2338	202	58	state	state	NOUN
admet-2338	202	59	[	[	X
admet-2338	202	60	35	35	NUM
admet-2338	202	61	]	]	PUNCT
admet-2338	202	62	.	.	PUNCT
admet-2338	203	1	the	the	DET
admet-2338	203	2	amorphous	amorphous	ADJ
admet-2338	203	3	nature	nature	NOUN
admet-2338	203	4	of	of	ADP
admet-2338	203	5	sfn	sfn	PROPN
admet-2338	203	6	in	in	ADP
admet-2338	203	7	ssd	ssd	NOUN
admet-2338	203	8	can	can	AUX
admet-2338	203	9	be	be	AUX
admet-2338	203	10	attributed	attribute	VERB
admet-2338	203	11	to	to	ADP
admet-2338	203	12	improvement	improvement	NOUN
admet-2338	203	13	in	in	ADP
admet-2338	203	14	solubility	solubility	NOUN
admet-2338	203	15	.	.	PUNCT
admet-2338	204	1	scanning	scan	VERB
admet-2338	204	2	electronic	electronic	ADJ
admet-2338	204	3	microscopy	microscopy	NOUN
admet-2338	204	4	the	the	DET
admet-2338	204	5	surface	surface	NOUN
admet-2338	204	6	morphology	morphology	NOUN
admet-2338	204	7	of	of	ADP
admet-2338	204	8	pure	pure	ADJ
admet-2338	204	9	sfn	sfn	PROPN
admet-2338	204	10	,	,	PUNCT
admet-2338	204	11	nu2	nu2	PROPN
admet-2338	204	12	and	and	CCONJ
admet-2338	204	13	sfn	sfn	PROPN
admet-2338	204	14	-	-	PUNCT
admet-2338	204	15	ssd	ssd	NOUN
admet-2338	204	16	was	be	AUX
admet-2338	204	17	studied	study	VERB
admet-2338	204	18	using	use	VERB
admet-2338	204	19	sem	sem	NOUN
admet-2338	204	20	,	,	PUNCT
admet-2338	204	21	as	as	SCONJ
admet-2338	204	22	shown	show	VERB
admet-2338	204	23	in	in	ADP
admet-2338	204	24	the	the	DET
admet-2338	204	25	figure	figure	NOUN
admet-2338	204	26	6	6	NUM
admet-2338	204	27	.	.	PUNCT
admet-2338	205	1	the	the	DET
admet-2338	205	2	pure	pure	ADJ
admet-2338	205	3	sfn	sfn	PROPN
admet-2338	205	4	showed	show	VERB
admet-2338	205	5	irregular	irregular	ADJ
admet-2338	205	6	crystals	crystal	NOUN
admet-2338	205	7	with	with	ADP
admet-2338	205	8	a	a	DET
admet-2338	205	9	plane	plane	NOUN
admet-2338	205	10	surface	surface	NOUN
admet-2338	205	11	,	,	PUNCT
admet-2338	205	12	while	while	SCONJ
admet-2338	205	13	nu2	nu2	NOUN
admet-2338	205	14	showed	show	VERB
admet-2338	205	15	smooth	smooth	ADJ
admet-2338	205	16	spherical	spherical	ADJ
admet-2338	205	17	,	,	PUNCT
admet-2338	205	18	roundedged	roundedge	VERB
admet-2338	205	19	,	,	PUNCT
admet-2338	205	20	non	non	ADJ
admet-2338	205	21	-	-	ADJ
admet-2338	205	22	uniform	uniform	ADJ
admet-2338	205	23	-	-	PUNCT
admet-2338	205	24	sized	sized	ADJ
admet-2338	205	25	amorphous	amorphous	ADJ
admet-2338	205	26	particles	particle	NOUN
admet-2338	205	27	.	.	PUNCT
admet-2338	206	1	the	the	DET
admet-2338	206	2	sfn	sfn	PROPN
admet-2338	206	3	-	-	PUNCT
admet-2338	206	4	ssd	ssd	NOUN
admet-2338	206	5	revealed	reveal	VERB
admet-2338	206	6	the	the	DET
admet-2338	206	7	deposition	deposition	NOUN
admet-2338	206	8	of	of	ADP
admet-2338	206	9	a	a	DET
admet-2338	206	10	fine	fine	ADJ
admet-2338	206	11	microcrystal	microcrystal	NOUN
admet-2338	206	12	of	of	ADP
admet-2338	206	13	sfn	sfn	PROPN
admet-2338	206	14	and	and	CCONJ
admet-2338	206	15	surfactant	surfactant	NOUN
admet-2338	206	16	on	on	ADP
admet-2338	206	17	the	the	DET
admet-2338	206	18	surface	surface	NOUN
admet-2338	206	19	of	of	ADP
admet-2338	206	20	nu2	nu2	PROPN
admet-2338	206	21	particles	particle	NOUN
admet-2338	206	22	.	.	PUNCT
admet-2338	207	1	the	the	DET
admet-2338	207	2	adsorption	adsorption	NOUN
admet-2338	207	3	of	of	ADP
admet-2338	207	4	an	an	DET
admet-2338	207	5	sfn	sfn	NOUN
admet-2338	207	6	on	on	ADP
admet-2338	207	7	the	the	DET
admet-2338	207	8	nu2	nu2	PROPN
admet-2338	207	9	surface	surface	NOUN
admet-2338	207	10	leads	lead	VERB
admet-2338	207	11	to	to	ADP
admet-2338	207	12	the	the	DET
admet-2338	207	13	formation	formation	NOUN
admet-2338	207	14	of	of	ADP
admet-2338	207	15	a	a	DET
admet-2338	207	16	rough	rough	ADJ
admet-2338	207	17	surface	surface	NOUN
admet-2338	207	18	of	of	ADP
admet-2338	207	19	the	the	DET
admet-2338	207	20	adsorbent	adsorbent	NOUN
admet-2338	207	21	,	,	PUNCT
admet-2338	207	22	indicating	indicate	VERB
admet-2338	207	23	the	the	DET
admet-2338	207	24	formation	formation	NOUN
admet-2338	207	25	ssd	ssd	NOUN
admet-2338	208	1	[	[	X
admet-2338	208	2	36,37	36,37	X
admet-2338	208	3	]	]	PUNCT
admet-2338	208	4	.	.	PUNCT
admet-2338	209	1	figure	figure	NOUN
admet-2338	209	2	6	6	NUM
admet-2338	209	3	.	.	PUNCT
admet-2338	210	1	scanning	scan	VERB
admet-2338	210	2	electron	electron	NOUN
admet-2338	210	3	microscopy	microscopy	NOUN
admet-2338	210	4	of	of	ADP
admet-2338	210	5	a	a	DET
admet-2338	210	6	sfn	sfn	PROPN
admet-2338	210	7	,	,	PUNCT
admet-2338	210	8	b	b	PROPN
admet-2338	210	9	neusilin	neusilin	PROPN
admet-2338	210	10	us2	us2	PROPN
admet-2338	210	11	,	,	PUNCT
admet-2338	210	12	c	c	PROPN
admet-2338	210	13	and	and	CCONJ
admet-2338	210	14	d	d	PROPN
admet-2338	210	15	sfn	sfn	PROPN
admet-2338	210	16	-	-	PUNCT
admet-2338	210	17	ssd	ssd	NOUN
admet-2338	210	18	differential	differential	NOUN
admet-2338	210	19	scanning	scanning	NOUN
admet-2338	210	20	calorimetry	calorimetry	NOUN
admet-2338	210	21	the	the	DET
admet-2338	210	22	thermal	thermal	ADJ
admet-2338	210	23	behaviour	behaviour	NOUN
admet-2338	210	24	of	of	ADP
admet-2338	210	25	sfn	sfn	PROPN
admet-2338	210	26	,	,	PUNCT
admet-2338	210	27	nu2	nu2	INTJ
admet-2338	210	28	,	,	PUNCT
admet-2338	210	29	and	and	CCONJ
admet-2338	210	30	the	the	DET
admet-2338	210	31	sfn	sfn	PROPN
admet-2338	210	32	-	-	PUNCT
admet-2338	210	33	ssd	ssd	NOUN
admet-2338	210	34	were	be	AUX
admet-2338	210	35	studied	study	VERB
admet-2338	210	36	using	use	VERB
admet-2338	210	37	dsc	dsc	NOUN
admet-2338	210	38	.	.	PUNCT
admet-2338	211	1	as	as	SCONJ
admet-2338	211	2	shown	show	VERB
admet-2338	211	3	in	in	ADP
admet-2338	211	4	figure	figure	NOUN
admet-2338	211	5	7	7	NUM
admet-2338	211	6	,	,	PUNCT
admet-2338	211	7	the	the	DET
admet-2338	211	8	sfn	sfn	NOUN
admet-2338	211	9	showed	show	VERB
admet-2338	211	10	a	a	DET
admet-2338	211	11	sharp	sharp	ADJ
admet-2338	211	12	melting	melting	NOUN
admet-2338	211	13	endotherm	endotherm	NOUN
admet-2338	211	14	event	event	NOUN
admet-2338	211	15	at	at	ADP
admet-2338	211	16	236.39	236.39	NUM
admet-2338	211	17	°	°	ADP
admet-2338	211	18	c	c	NOUN
admet-2338	211	19	with	with	ADP
admet-2338	211	20	an	an	DET
admet-2338	211	21	enthalpy	enthalpy	NOUN
admet-2338	211	22	of	of	ADP
admet-2338	211	23	fusion	fusion	NOUN
admet-2338	211	24	of	of	ADP
admet-2338	211	25	-25.09	-25.09	PROPN
admet-2338	211	26	j	j	PROPN
admet-2338	211	27	/	/	SYM
admet-2338	211	28	g	g	PROPN
admet-2338	211	29	,	,	PUNCT
admet-2338	211	30	indicating	indicate	VERB
admet-2338	211	31	crystalline	crystalline	ADJ
admet-2338	211	32	nature	nature	NOUN
admet-2338	211	33	.	.	PUNCT
admet-2338	212	1	nu2	nu2	PROPN
admet-2338	212	2	showed	show	VERB
admet-2338	212	3	a	a	DET
admet-2338	212	4	broad	broad	ADJ
admet-2338	212	5	melting	melting	NOUN
admet-2338	212	6	peak	peak	NOUN
admet-2338	212	7	at	at	ADP
admet-2338	212	8	212.84	212.84	NUM
admet-2338	212	9	°	°	ADP
admet-2338	212	10	c	c	NOUN
admet-2338	212	11	(	(	PUNCT
admet-2338	212	12	δh	δh	X
admet-2338	212	13	is	be	AUX
admet-2338	212	14	-3.42	-3.42	NUM
admet-2338	212	15	j	j	PROPN
admet-2338	212	16	/	/	SYM
admet-2338	212	17	g	g	PROPN
admet-2338	212	18	)	)	PUNCT
admet-2338	212	19	,	,	PUNCT
admet-2338	212	20	indicating	indicate	VERB
admet-2338	212	21	its	its	PRON
admet-2338	212	22	amorphous	amorphous	ADJ
admet-2338	212	23	nature	nature	NOUN
admet-2338	212	24	.	.	PUNCT
admet-2338	213	1	the	the	DET
admet-2338	213	2	sfn	sfn	PROPN
admet-2338	213	3	-	-	PUNCT
admet-2338	213	4	ssd	ssd	NOUN
admet-2338	213	5	showed	show	VERB
admet-2338	213	6	a	a	DET
admet-2338	213	7	single	single	ADJ
admet-2338	213	8	broad	broad	ADJ
admet-2338	213	9	peak	peak	NOUN
admet-2338	213	10	at	at	ADP
admet-2338	213	11	210.16	210.16	NUM
admet-2338	213	12	°	°	ADP
admet-2338	213	13	c	c	NOUN
admet-2338	213	14	with	with	ADP
admet-2338	213	15	an	an	DET
admet-2338	213	16	enthalpy	enthalpy	NOUN
admet-2338	213	17	value	value	NOUN
admet-2338	213	18	of	of	ADP
admet-2338	213	19	-2.72	-2.72	PROPN
admet-2338	213	20	j	j	PROPN
admet-2338	213	21	/	/	SYM
admet-2338	213	22	g	g	PROPN
admet-2338	213	23	,	,	PUNCT
admet-2338	213	24	indicating	indicate	VERB
admet-2338	213	25	the	the	DET
admet-2338	213	26	nu2	nu2	PROPN
admet-2338	213	27	peak	peak	NOUN
admet-2338	213	28	with	with	ADP
admet-2338	213	29	decreased	decrease	VERB
admet-2338	213	30	melting	melting	NOUN
admet-2338	213	31	point	point	NOUN
admet-2338	213	32	and	and	CCONJ
admet-2338	213	33	enthalpy	enthalpy	NOUN
admet-2338	213	34	of	of	ADP
admet-2338	213	35	fusion	fusion	NOUN
admet-2338	213	36	further	far	ADV
admet-2338	213	37	indicates	indicate	VERB
admet-2338	213	38	the	the	DET
admet-2338	213	39	incorporation	incorporation	NOUN
admet-2338	213	40	of	of	ADP
admet-2338	213	41	sfn	sfn	PROPN
admet-2338	213	42	into	into	ADP
admet-2338	213	43	ssd	ssd	PROPN
admet-2338	213	44	.	.	PUNCT
admet-2338	214	1	however	however	ADV
admet-2338	214	2	,	,	PUNCT
admet-2338	214	3	the	the	DET
admet-2338	214	4	sfn	sfn	PROPN
admet-2338	214	5	peak	peak	NOUN
admet-2338	214	6	disappeared	disappear	VERB
admet-2338	214	7	in	in	ADP
admet-2338	214	8	sfn	sfn	PROPN
admet-2338	214	9	-	-	PUNCT
admet-2338	214	10	ssd	ssd	NOUN
admet-2338	214	11	,	,	PUNCT
admet-2338	214	12	indicating	indicate	VERB
admet-2338	214	13	the	the	DET
admet-2338	214	14	conversion	conversion	NOUN
admet-2338	214	15	of	of	ADP
admet-2338	214	16	sfn	sfn	PROPN
admet-2338	214	17	into	into	ADP
admet-2338	214	18	the	the	DET
admet-2338	214	19	amorphous	amorphous	ADJ
admet-2338	214	20	form	form	NOUN
admet-2338	214	21	[	[	X
admet-2338	214	22	38	38	NUM
admet-2338	214	23	]	]	PUNCT
admet-2338	214	24	.	.	PUNCT
admet-2338	215	1	the	the	DET
admet-2338	215	2	formation	formation	NOUN
admet-2338	215	3	of	of	ADP
admet-2338	215	4	amorphous	amorphous	ADJ
admet-2338	215	5	ssd	ssd	NOUN
admet-2338	215	6	could	could	AUX
admet-2338	215	7	result	result	VERB
admet-2338	215	8	in	in	ADP
admet-2338	215	9	an	an	DET
admet-2338	215	10	improvement	improvement	NOUN
admet-2338	215	11	in	in	ADP
admet-2338	215	12	dissolution	dissolution	ADJ
admet-2338	215	13	rate	rate	NOUN
admet-2338	215	14	due	due	ADP
admet-2338	215	15	to	to	ADP
admet-2338	215	16	the	the	DET
admet-2338	215	17	solubilizing	solubilize	VERB
admet-2338	215	18	effect	effect	NOUN
admet-2338	215	19	of	of	ADP
admet-2338	215	20	a	a	DET
admet-2338	215	21	carrier	carrier	NOUN
admet-2338	215	22	,	,	PUNCT
admet-2338	215	23	improved	improved	ADJ
admet-2338	215	24	wetting	wetting	NOUN
admet-2338	215	25	,	,	PUNCT
admet-2338	215	26	and	and	CCONJ
admet-2338	215	27	a	a	DET
admet-2338	215	28	reduction	reduction	NOUN
admet-2338	215	29	in	in	ADP
admet-2338	215	30	the	the	DET
admet-2338	215	31	crystallinity	crystallinity	NOUN
admet-2338	215	32	of	of	ADP
admet-2338	215	33	the	the	DET
admet-2338	215	34	sfn	sfn	PROPN
admet-2338	215	35	[	[	X
admet-2338	215	36	39,40	39,40	NUM
admet-2338	215	37	]	]	PUNCT
admet-2338	215	38	.	.	PUNCT
admet-2338	216	1	evaluation	evaluation	NOUN
admet-2338	216	2	of	of	ADP
admet-2338	216	3	sfn	sfn	PROPN
admet-2338	216	4	-	-	PUNCT
admet-2338	216	5	ssd	ssd	PROPN
admet-2338	216	6	and	and	CCONJ
admet-2338	216	7	sfn	sfn	ADJ
admet-2338	216	8	immediate	immediate	ADJ
admet-2338	216	9	-	-	PUNCT
admet-2338	216	10	release	release	NOUN
admet-2338	216	11	tablet	tablet	NOUN
admet-2338	216	12	the	the	DET
admet-2338	216	13	sfn	sfn	PROPN
admet-2338	216	14	-	-	PUNCT
admet-2338	216	15	ssd	ssd	NOUN
admet-2338	216	16	granules	granule	NOUN
admet-2338	216	17	showed	show	VERB
admet-2338	216	18	good	good	ADJ
admet-2338	216	19	flow	flow	NOUN
admet-2338	216	20	properties	property	NOUN
admet-2338	216	21	such	such	ADJ
admet-2338	216	22	as	as	ADP
admet-2338	216	23	bulk	bulk	ADJ
admet-2338	216	24	density	density	NOUN
admet-2338	216	25	of	of	ADP
admet-2338	216	26	0.393	0.393	NUM
admet-2338	216	27	g	g	NOUN
admet-2338	216	28	/	/	SYM
admet-2338	216	29	ml	ml	NOUN
admet-2338	216	30	,	,	PUNCT
admet-2338	216	31	tapped	tap	VERB
admet-2338	216	32	density	density	NOUN
admet-2338	216	33	of	of	ADP
admet-2338	216	34	0.460	0.460	NUM
admet-2338	216	35	g	g	NOUN
admet-2338	216	36	/	/	SYM
admet-2338	216	37	ml	ml	PROPN
admet-2338	216	38	,	,	PUNCT
admet-2338	216	39	carr	carr	PROPN
admet-2338	216	40	’s	’s	PART
admet-2338	216	41	compressibility	compressibility	NOUN
admet-2338	216	42	index	index	NOUN
admet-2338	216	43	of	of	ADP
admet-2338	216	44	14.5	14.5	NUM
admet-2338	216	45	%	%	NOUN
admet-2338	216	46	,	,	PUNCT
admet-2338	216	47	hausner	hausner	NOUN
admet-2338	216	48	’s	’s	PART
admet-2338	216	49	ratio	ratio	NOUN
admet-2338	216	50	of	of	ADP
admet-2338	216	51	1.17	1.17	NUM
admet-2338	216	52	and	and	CCONJ
admet-2338	216	53	angle	angle	NOUN
admet-2338	216	54	of	of	ADP
admet-2338	216	55	repose	repose	NOUN
admet-2338	216	56	of	of	ADP
admet-2338	216	57	27.52	27.52	NUM
admet-2338	216	58	°	°	NOUN
admet-2338	216	59	.	.	PUNCT
admet-2338	217	1	as	as	SCONJ
admet-2338	217	2	shown	show	VERB
admet-2338	217	3	in	in	ADP
admet-2338	217	4	table	table	NOUN
admet-2338	217	5	4	4	NUM
admet-2338	217	6	,	,	PUNCT
admet-2338	217	7	both	both	DET
admet-2338	217	8	tablets	tablet	NOUN
admet-2338	217	9	are	be	AUX
admet-2338	217	10	within	within	ADP
admet-2338	217	11	the	the	DET
admet-2338	217	12	pharmacopeial	pharmacopeial	ADJ
admet-2338	217	13	limit	limit	NOUN
admet-2338	217	14	of	of	ADP
admet-2338	217	15	hardness	hardness	NOUN
admet-2338	217	16	,	,	PUNCT
admet-2338	217	17	thickness	thickness	NOUN
admet-2338	217	18	,	,	PUNCT
admet-2338	217	19	diameter	diameter	NOUN
admet-2338	217	20	,	,	PUNCT
admet-2338	217	21	weight	weight	NOUN
admet-2338	217	22	admet	admet	PROPN
admet-2338	217	23	&	&	CCONJ
admet-2338	217	24	dmpk	dmpk	PROPN
admet-2338	217	25	12(4	12(4	PROPN
admet-2338	217	26	)	)	PUNCT
admet-2338	217	27	(	(	PUNCT
admet-2338	217	28	2024	2024	NUM
admet-2338	217	29	)	)	PUNCT
admet-2338	217	30	687	687	NUM
admet-2338	217	31	-	-	SYM
admet-2338	217	32	702	702	NUM
admet-2338	217	33	neusilin	neusilin	PROPN
admet-2338	217	34	us2	us2	PROPN
admet-2338	217	35	based	base	VERB
admet-2338	217	36	surface	surface	NOUN
admet-2338	217	37	solid	solid	ADJ
admet-2338	217	38	dispersion	dispersion	NOUN
admet-2338	217	39	of	of	ADP
admet-2338	217	40	sorafenib	sorafenib	NOUN
admet-2338	217	41	tosylate	tosylate	VERB
admet-2338	217	42	doi	doi	NOUN
admet-2338	217	43	:	:	PUNCT
admet-2338	217	44	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	NOUN
admet-2338	217	45	697	697	NUM
admet-2338	217	46	variation	variation	NOUN
admet-2338	217	47	and	and	CCONJ
admet-2338	217	48	friability	friability	NOUN
admet-2338	217	49	.	.	PUNCT
admet-2338	218	1	the	the	DET
admet-2338	218	2	disintegration	disintegration	NOUN
admet-2338	218	3	time	time	NOUN
admet-2338	218	4	was	be	AUX
admet-2338	218	5	in	in	ADP
admet-2338	218	6	the	the	DET
admet-2338	218	7	pharmacopeial	pharmacopeial	ADJ
admet-2338	218	8	immediate	immediate	ADJ
admet-2338	218	9	release	release	NOUN
admet-2338	218	10	tablet	tablet	NOUN
admet-2338	218	11	limit	limit	NOUN
admet-2338	218	12	,	,	PUNCT
admet-2338	218	13	which	which	PRON
admet-2338	218	14	may	may	AUX
admet-2338	218	15	be	be	AUX
admet-2338	218	16	due	due	ADJ
admet-2338	218	17	to	to	ADP
admet-2338	218	18	the	the	DET
admet-2338	218	19	capillary	capillary	ADJ
admet-2338	218	20	action	action	NOUN
admet-2338	218	21	that	that	PRON
admet-2338	218	22	facilitates	facilitate	VERB
admet-2338	218	23	the	the	DET
admet-2338	218	24	absorption	absorption	NOUN
admet-2338	218	25	of	of	ADP
admet-2338	218	26	water	water	NOUN
admet-2338	218	27	,	,	PUNCT
admet-2338	218	28	leading	lead	VERB
admet-2338	218	29	to	to	ADP
admet-2338	218	30	higher	high	ADJ
admet-2338	218	31	water	water	NOUN
admet-2338	218	32	solubility	solubility	NOUN
admet-2338	218	33	.	.	PUNCT
admet-2338	219	1	moreover	moreover	ADV
admet-2338	219	2	,	,	PUNCT
admet-2338	219	3	the	the	DET
admet-2338	219	4	use	use	NOUN
admet-2338	219	5	of	of	ADP
admet-2338	219	6	mcc	mcc	PROPN
admet-2338	219	7	induces	induce	VERB
admet-2338	219	8	faster	fast	ADJ
admet-2338	219	9	disintegration	disintegration	NOUN
admet-2338	219	10	.	.	PUNCT
admet-2338	220	1	figure	figure	NOUN
admet-2338	220	2	7	7	NUM
admet-2338	220	3	.	.	PUNCT
admet-2338	220	4	differential	differential	PROPN
admet-2338	220	5	scanning	scan	VERB
admet-2338	220	6	calorimetry	calorimetry	NOUN
admet-2338	220	7	of	of	ADP
admet-2338	220	8	a	a	DET
admet-2338	220	9	sfn	sfn	PROPN
admet-2338	220	10	,	,	PUNCT
admet-2338	220	11	b	b	PROPN
admet-2338	220	12	sodium	sodium	NOUN
admet-2338	220	13	dodecyl	dodecyl	NOUN
admet-2338	220	14	sulphate	sulphate	NOUN
admet-2338	220	15	,	,	PUNCT
admet-2338	220	16	c	c	PROPN
admet-2338	220	17	neusilin	neusilin	PROPN
admet-2338	220	18	us2	us2	PROPN
admet-2338	220	19	and	and	CCONJ
admet-2338	220	20	d	d	PROPN
admet-2338	220	21	sfn	sfn	PROPN
admet-2338	220	22	-	-	PUNCT
admet-2338	220	23	ssd	ssd	NOUN
admet-2338	220	24	table	table	NOUN
admet-2338	220	25	4	4	NUM
admet-2338	220	26	.	.	PUNCT
admet-2338	221	1	evaluation	evaluation	NOUN
admet-2338	221	2	of	of	ADP
admet-2338	221	3	sfn	sfn	PROPN
admet-2338	221	4	-	-	PUNCT
admet-2338	221	5	ssd	ssd	PROPN
admet-2338	221	6	and	and	CCONJ
admet-2338	221	7	sfn	sfn	ADJ
admet-2338	221	8	immediate	immediate	ADJ
admet-2338	221	9	release	release	NOUN
admet-2338	221	10	tablet	tablet	NOUN
admet-2338	221	11	parameters	parameter	NOUN
admet-2338	221	12	sfn	sfn	PROPN
admet-2338	221	13	-	-	PUNCT
admet-2338	221	14	ssd	ssd	NOUN
admet-2338	221	15	tablet	tablet	NOUN
admet-2338	221	16	(	(	PUNCT
admet-2338	221	17	b1	b1	NOUN
admet-2338	221	18	)	)	PUNCT
admet-2338	221	19	pure	pure	ADJ
admet-2338	221	20	sfn	sfn	PROPN
admet-2338	221	21	tablet	tablet	NOUN
admet-2338	221	22	(	(	PUNCT
admet-2338	221	23	b2	b2	NOUN
admet-2338	221	24	)	)	PUNCT
admet-2338	221	25	hardness	hardness	NOUN
admet-2338	221	26	,	,	PUNCT
admet-2338	221	27	kg	kg	PROPN
admet-2338	221	28	/	/	SYM
admet-2338	221	29	cm2	cm2	PROPN
admet-2338	221	30	4.21	4.21	NUM
admet-2338	221	31	±	±	NUM
admet-2338	221	32	0.36	0.36	NUM
admet-2338	221	33	4.73	4.73	NUM
admet-2338	221	34	±	±	NUM
admet-2338	221	35	0.15	0.15	NUM
admet-2338	221	36	thickness	thickness	NOUN
admet-2338	221	37	,	,	PUNCT
admet-2338	221	38	mm	mm	PROPN
admet-2338	221	39	5.53	5.53	NUM
admet-2338	221	40	±	±	NUM
admet-2338	221	41	0.15	0.15	NUM
admet-2338	221	42	*	*	NOUN
admet-2338	221	43	*	*	PUNCT
admet-2338	221	44	5.83	5.83	NUM
admet-2338	221	45	±	±	NUM
admet-2338	221	46	0.08	0.08	NUM
admet-2338	221	47	diameter	diameter	NOUN
admet-2338	221	48	,	,	PUNCT
admet-2338	221	49	mm	mm	PROPN
admet-2338	221	50	12.03	12.03	NUM
admet-2338	221	51	±	±	NUM
admet-2338	221	52	0.06	0.06	NUM
admet-2338	221	53	12.00	12.00	NUM
admet-2338	221	54	±	±	NUM
admet-2338	221	55	0.00	0.00	NUM
admet-2338	221	56	weight	weight	NOUN
admet-2338	221	57	variation	variation	NOUN
admet-2338	221	58	passes	pass	NOUN
admet-2338	221	59	(	(	PUNCT
admet-2338	221	60	average	average	ADJ
admet-2338	221	61	weight	weight	NOUN
admet-2338	221	62	507.5	507.5	NUM
admet-2338	221	63	mg	mg	NOUN
admet-2338	221	64	)	)	PUNCT
admet-2338	221	65	*	*	PUNCT
admet-2338	222	1	*	*	PUNCT
admet-2338	222	2	passes	pass	VERB
admet-2338	222	3	(	(	PUNCT
admet-2338	222	4	average	average	ADJ
admet-2338	222	5	weight	weight	NOUN
admet-2338	222	6	507.1	507.1	NUM
admet-2338	222	7	mg	mg	NOUN
admet-2338	222	8	)	)	PUNCT
admet-2338	222	9	friability	friability	NOUN
admet-2338	222	10	,	,	PUNCT
admet-2338	222	11	%	%	NOUN
admet-2338	222	12	0.39	0.39	NUM
admet-2338	222	13	±	±	NUM
admet-2338	222	14	0.06	0.06	NUM
admet-2338	222	15	0.28	0.28	NUM
admet-2338	222	16	±	±	NUM
admet-2338	222	17	0.36	0.36	NUM
admet-2338	222	18	disintegration	disintegration	NOUN
admet-2338	222	19	,	,	PUNCT
admet-2338	222	20	min	min	NOUN
admet-2338	222	21	2.87	2.87	NUM
admet-2338	222	22	±	±	NUM
admet-2338	222	23	0.35	0.35	NUM
admet-2338	222	24	*	*	SYM
admet-2338	222	25	2.27	2.27	NUM
admet-2338	222	26	±	±	NUM
admet-2338	222	27	0.42	0.42	NUM
admet-2338	222	28	all	all	DET
admet-2338	222	29	the	the	DET
admet-2338	222	30	determinations	determination	NOUN
admet-2338	222	31	are	be	AUX
admet-2338	222	32	performed	perform	VERB
admet-2338	222	33	in	in	ADP
admet-2338	222	34	triplicate	triplicate	NOUN
admet-2338	222	35	,	,	PUNCT
admet-2338	222	36	and	and	CCONJ
admet-2338	222	37	values	value	NOUN
admet-2338	222	38	are	be	AUX
admet-2338	222	39	expressed	express	VERB
admet-2338	222	40	as	as	SCONJ
admet-2338	222	41	the	the	DET
admet-2338	222	42	mean	mean	ADJ
admet-2338	222	43	data	datum	NOUN
admet-2338	222	44	are	be	AUX
admet-2338	222	45	mean	mean	NOUN
admet-2338	222	46	±	±	NUM
admet-2338	222	47	sd	sd	NOUN
admet-2338	222	48	(	(	PUNCT
admet-2338	222	49	n	n	NOUN
admet-2338	222	50	=	=	SYM
admet-2338	222	51	3	3	NUM
admet-2338	222	52	)	)	PUNCT
admet-2338	222	53	;	;	PUNCT
admet-2338	222	54	*	*	PUNCT
admet-2338	222	55	p	p	NOUN
admet-2338	222	56	≤	≤	NOUN
admet-2338	222	57	0.1	0.1	NUM
admet-2338	222	58	(	(	PUNCT
admet-2338	222	59	not	not	PART
admet-2338	222	60	statistically	statistically	ADV
admet-2338	222	61	significant	significant	ADJ
admet-2338	222	62	)	)	PUNCT
admet-2338	222	63	,	,	PUNCT
admet-2338	222	64	*	*	PUNCT
admet-2338	222	65	*	*	PUNCT
admet-2338	222	66	p	p	X
admet-2338	222	67	≤	≤	ADJ
admet-2338	222	68	0.01	0.01	NUM
admet-2338	222	69	(	(	PUNCT
admet-2338	222	70	statistically	statistically	ADV
admet-2338	222	71	significant	significant	ADJ
admet-2338	222	72	)	)	PUNCT
admet-2338	222	73	in	in	ADP
admet-2338	222	74	vitro	vitro	X
admet-2338	222	75	dissolution	dissolution	PROPN
admet-2338	222	76	studies	study	NOUN
admet-2338	222	77	the	the	DET
admet-2338	222	78	in	in	ADP
admet-2338	222	79	vitro	vitro	X
admet-2338	222	80	release	release	NOUN
admet-2338	222	81	profiles	profile	NOUN
admet-2338	222	82	of	of	ADP
admet-2338	222	83	sfn	sfn	PROPN
admet-2338	222	84	-	-	PUNCT
admet-2338	222	85	ssd	ssd	NOUN
admet-2338	222	86	and	and	CCONJ
admet-2338	222	87	pure	pure	ADJ
admet-2338	222	88	sfn	sfn	NOUN
admet-2338	222	89	tablets	tablet	NOUN
admet-2338	222	90	were	be	AUX
admet-2338	222	91	shown	show	VERB
admet-2338	222	92	in	in	ADP
admet-2338	222	93	figure	figure	NOUN
admet-2338	222	94	8	8	NUM
admet-2338	222	95	.	.	PUNCT
admet-2338	223	1	the	the	DET
admet-2338	223	2	sfn	sfn	PROPN
admet-2338	223	3	-	-	PUNCT
admet-2338	223	4	ssd	ssd	NOUN
admet-2338	223	5	tablet	tablet	NOUN
admet-2338	223	6	showed	show	VERB
admet-2338	223	7	an	an	DET
admet-2338	223	8	initial	initial	ADJ
admet-2338	223	9	burst	burst	ADJ
admet-2338	223	10	release	release	NOUN
admet-2338	223	11	due	due	ADP
admet-2338	223	12	to	to	ADP
admet-2338	223	13	micellar	micellar	NOUN
admet-2338	223	14	solubility	solubility	NOUN
admet-2338	223	15	of	of	ADP
admet-2338	223	16	sds	sds	PROPN
admet-2338	223	17	with	with	ADP
admet-2338	223	18	a	a	DET
admet-2338	223	19	cumulative	cumulative	ADJ
admet-2338	223	20	release	release	NOUN
admet-2338	223	21	of	of	ADP
admet-2338	223	22	97.13	97.13	NUM
admet-2338	223	23	%	%	NOUN
admet-2338	223	24	in	in	ADP
admet-2338	223	25	60	60	NUM
admet-2338	223	26	min	min	NOUN
admet-2338	223	27	.	.	PUNCT
admet-2338	224	1	this	this	PRON
admet-2338	224	2	might	might	AUX
admet-2338	224	3	be	be	AUX
admet-2338	224	4	the	the	DET
admet-2338	224	5	reason	reason	NOUN
admet-2338	224	6	for	for	ADP
admet-2338	224	7	the	the	DET
admet-2338	224	8	rapid	rapid	ADJ
admet-2338	224	9	diffusion	diffusion	NOUN
admet-2338	224	10	of	of	ADP
admet-2338	224	11	sfn	sfn	PROPN
admet-2338	224	12	,	,	PUNCT
admet-2338	224	13	which	which	PRON
admet-2338	224	14	was	be	AUX
admet-2338	224	15	absorbed	absorb	VERB
admet-2338	224	16	on	on	ADP
admet-2338	224	17	the	the	DET
admet-2338	224	18	surface	surface	NOUN
admet-2338	224	19	of	of	ADP
admet-2338	224	20	micelles	micelle	NOUN
admet-2338	224	21	,	,	PUNCT
admet-2338	224	22	or	or	CCONJ
admet-2338	224	23	due	due	ADP
admet-2338	224	24	to	to	ADP
admet-2338	224	25	the	the	DET
admet-2338	224	26	disruption	disruption	NOUN
admet-2338	224	27	of	of	ADP
admet-2338	224	28	the	the	DET
admet-2338	224	29	micellar	micellar	ADJ
admet-2338	224	30	structure	structure	NOUN
admet-2338	224	31	due	due	ADP
admet-2338	224	32	to	to	ADP
admet-2338	224	33	ph	ph	NOUN
admet-2338	224	34	or	or	CCONJ
admet-2338	224	35	the	the	DET
admet-2338	224	36	presence	presence	NOUN
admet-2338	224	37	of	of	ADP
admet-2338	224	38	ionic	ionic	ADJ
admet-2338	224	39	molecules	molecule	NOUN
admet-2338	224	40	in	in	ADP
admet-2338	224	41	dissolution	dissolution	ADJ
admet-2338	224	42	media	medium	NOUN
admet-2338	224	43	.	.	PUNCT
admet-2338	225	1	pure	pure	ADJ
admet-2338	225	2	sfn	sfn	PROPN
admet-2338	225	3	tablets	tablet	NOUN
admet-2338	225	4	showed	show	VERB
admet-2338	225	5	29.93	29.93	NUM
admet-2338	225	6	%	%	NOUN
admet-2338	225	7	release	release	NOUN
admet-2338	225	8	at	at	ADP
admet-2338	225	9	the	the	DET
admet-2338	225	10	same	same	ADJ
admet-2338	225	11	time	time	NOUN
admet-2338	225	12	,	,	PUNCT
admet-2338	225	13	indicating	indicate	VERB
admet-2338	225	14	poor	poor	ADJ
admet-2338	225	15	aqueous	aqueous	ADJ
admet-2338	225	16	solubility	solubility	NOUN
admet-2338	225	17	of	of	ADP
admet-2338	225	18	sfn	sfn	PROPN
admet-2338	225	19	.	.	PUNCT
admet-2338	226	1	further	far	ADV
admet-2338	226	2	,	,	PUNCT
admet-2338	226	3	the	the	DET
admet-2338	226	4	rapid	rapid	ADJ
admet-2338	226	5	release	release	NOUN
admet-2338	226	6	of	of	ADP
admet-2338	226	7	sfn	sfn	PROPN
admet-2338	226	8	from	from	ADP
admet-2338	226	9	the	the	DET
admet-2338	226	10	sfn	sfn	PROPN
admet-2338	226	11	-	-	PUNCT
admet-2338	226	12	ssd	ssd	NOUN
admet-2338	226	13	tablet	tablet	NOUN
admet-2338	226	14	was	be	AUX
admet-2338	226	15	due	due	ADJ
admet-2338	226	16	to	to	ADP
admet-2338	226	17	the	the	DET
admet-2338	226	18	improved	improve	VERB
admet-2338	226	19	aqueous	aqueous	ADJ
admet-2338	226	20	solubility	solubility	NOUN
admet-2338	226	21	of	of	ADP
admet-2338	226	22	sfn	sfn	NOUN
admet-2338	226	23	by	by	ADP
admet-2338	226	24	converting	convert	VERB
admet-2338	226	25	crystalline	crystalline	NOUN
admet-2338	226	26	to	to	ADP
admet-2338	226	27	amorphous	amorphous	ADJ
admet-2338	226	28	form	form	NOUN
admet-2338	226	29	with	with	ADP
admet-2338	226	30	a	a	DET
admet-2338	226	31	high	high	ADJ
admet-2338	226	32	energy	energy	NOUN
admet-2338	226	33	state	state	NOUN
admet-2338	226	34	in	in	ADP
admet-2338	226	35	ssd	ssd	PROPN
admet-2338	226	36	.	.	PUNCT
admet-2338	227	1	as	as	SCONJ
admet-2338	227	2	reported	report	VERB
admet-2338	227	3	in	in	ADP
admet-2338	227	4	the	the	DET
admet-2338	227	5	literature	literature	NOUN
admet-2338	227	6	,	,	PUNCT
admet-2338	227	7	the	the	DET
admet-2338	227	8	basic	basic	ADJ
admet-2338	227	9	mechanism	mechanism	NOUN
admet-2338	227	10	of	of	ADP
admet-2338	227	11	drug	drug	NOUN
admet-2338	227	12	dissolution	dissolution	NOUN
admet-2338	227	13	from	from	ADP
admet-2338	227	14	silica	silica	NOUN
admet-2338	227	15	-	-	PUNCT
admet-2338	227	16	based	base	VERB
admet-2338	227	17	adsorbents	adsorbent	NOUN
admet-2338	227	18	is	be	AUX
admet-2338	227	19	stronger	strong	ADJ
admet-2338	227	20	interactions	interaction	NOUN
admet-2338	227	21	between	between	ADP
admet-2338	227	22	the	the	DET
admet-2338	227	23	silica	silica	NOUN
admet-2338	227	24	and	and	CCONJ
admet-2338	227	25	water	water	NOUN
admet-2338	227	26	than	than	ADP
admet-2338	227	27	between	between	ADP
admet-2338	227	28	the	the	DET
admet-2338	227	29	silica	silica	NOUN
admet-2338	227	30	and	and	CCONJ
admet-2338	227	31	drug	drug	NOUN
admet-2338	227	32	due	due	ADP
admet-2338	227	33	to	to	ADP
admet-2338	227	34	hydrogen	hydrogen	NOUN
admet-2338	227	35	bonding	bonding	NOUN
admet-2338	227	36	.	.	PUNCT
admet-2338	228	1	in	in	ADP
admet-2338	228	2	ssd	ssd	PROPN
admet-2338	228	3	,	,	PUNCT
admet-2338	228	4	sfn	sfn	PROPN
admet-2338	228	5	formed	form	VERB
admet-2338	228	6	hydrogen	hydrogen	NOUN
admet-2338	228	7	bonds	bond	NOUN
admet-2338	228	8	with	with	ADP
admet-2338	228	9	nu2	nu2	PROPN
admet-2338	228	10	.	.	PUNCT
admet-2338	229	1	in	in	ADP
admet-2338	229	2	a	a	DET
admet-2338	229	3	dissolution	dissolution	NOUN
admet-2338	229	4	medium	medium	NOUN
admet-2338	229	5	,	,	PUNCT
admet-2338	229	6	the	the	DET
admet-2338	229	7	water	water	NOUN
admet-2338	229	8	molecules	molecule	NOUN
admet-2338	229	9	remove	remove	VERB
admet-2338	229	10	the	the	DET
admet-2338	229	11	drug	drug	NOUN
admet-2338	229	12	from	from	ADP
admet-2338	229	13	the	the	DET
admet-2338	229	14	adsorbent	adsorbent	NOUN
admet-2338	229	15	,	,	PUNCT
admet-2338	229	16	and	and	CCONJ
admet-2338	229	17	the	the	DET
admet-2338	229	18	drug	drug	NOUN
admet-2338	229	19	gets	get	VERB
admet-2338	230	1	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	PROPN
admet-2338	230	2	b.	b.	PROPN
admet-2338	230	3	kumar	kumar	PROPN
admet-2338	230	4	panda	panda	PROPN
admet-2338	230	5	et	et	PROPN
admet-2338	230	6	al	al	PROPN
admet-2338	230	7	.	.	PROPN
admet-2338	230	8	admet	admet	PROPN
admet-2338	230	9	&	&	CCONJ
admet-2338	230	10	dmpk	dmpk	PROPN
admet-2338	230	11	12(4	12(4	PROPN
admet-2338	230	12	)	)	PUNCT
admet-2338	230	13	(	(	PUNCT
admet-2338	230	14	2024	2024	NUM
admet-2338	230	15	)	)	PUNCT
admet-2338	230	16	687	687	NUM
admet-2338	230	17	-	-	SYM
admet-2338	230	18	702	702	NUM
admet-2338	230	19	698	698	NUM
admet-2338	230	20	solubilized	solubilize	VERB
admet-2338	230	21	in	in	ADP
admet-2338	230	22	the	the	DET
admet-2338	230	23	sheath	sheath	NOUN
admet-2338	230	24	layer	layer	NOUN
admet-2338	230	25	of	of	ADP
admet-2338	230	26	the	the	DET
admet-2338	230	27	adsorbent	adsorbent	NOUN
admet-2338	230	28	[	[	X
admet-2338	230	29	17,18	17,18	NUM
admet-2338	230	30	]	]	PUNCT
admet-2338	230	31	.	.	PUNCT
admet-2338	231	1	the	the	DET
admet-2338	231	2	stronger	strong	ADJ
admet-2338	231	3	hydrogen	hydrogen	NOUN
admet-2338	231	4	bond	bond	NOUN
admet-2338	231	5	formation	formation	NOUN
admet-2338	231	6	between	between	ADP
admet-2338	231	7	nu2	nu2	NOUN
admet-2338	231	8	and	and	CCONJ
admet-2338	231	9	water	water	NOUN
admet-2338	231	10	molecules	molecule	NOUN
admet-2338	231	11	causes	cause	VERB
admet-2338	231	12	the	the	DET
admet-2338	231	13	cleavage	cleavage	NOUN
admet-2338	231	14	of	of	ADP
admet-2338	231	15	the	the	DET
admet-2338	231	16	weaker	weak	ADJ
admet-2338	231	17	hydrogen	hydrogen	NOUN
admet-2338	231	18	bond	bond	NOUN
admet-2338	231	19	between	between	ADP
admet-2338	231	20	nu2	nu2	PROPN
admet-2338	231	21	-	-	PUNCT
admet-2338	231	22	sfn	sfn	PROPN
admet-2338	231	23	.	.	PUNCT
admet-2338	232	1	the	the	DET
admet-2338	232	2	sfn	sfn	PROPN
admet-2338	232	3	release	release	NOUN
admet-2338	232	4	from	from	ADP
admet-2338	232	5	ssd	ssd	NOUN
admet-2338	232	6	follows	follow	VERB
admet-2338	232	7	first	first	ADJ
admet-2338	232	8	-	-	PUNCT
admet-2338	232	9	order	order	NOUN
admet-2338	232	10	kinetics	kinetic	NOUN
admet-2338	232	11	(	(	PUNCT
admet-2338	232	12	r2	r2	PROPN
admet-2338	232	13	=	=	SYM
admet-2338	232	14	0.9839	0.9839	NUM
admet-2338	232	15	)	)	PUNCT
admet-2338	232	16	,	,	PUNCT
admet-2338	232	17	indicating	indicate	VERB
admet-2338	232	18	the	the	DET
admet-2338	232	19	drug	drug	NOUN
admet-2338	232	20	release	release	NOUN
admet-2338	232	21	depends	depend	VERB
admet-2338	232	22	on	on	ADP
admet-2338	232	23	the	the	DET
admet-2338	232	24	drug	drug	NOUN
admet-2338	232	25	concentration	concentration	NOUN
admet-2338	232	26	.	.	PUNCT
admet-2338	233	1	this	this	PRON
admet-2338	233	2	may	may	AUX
admet-2338	233	3	be	be	AUX
admet-2338	233	4	because	because	SCONJ
admet-2338	233	5	the	the	DET
admet-2338	233	6	drug	drug	NOUN
admet-2338	233	7	present	present	ADJ
admet-2338	233	8	on	on	ADP
admet-2338	233	9	the	the	DET
admet-2338	233	10	surface	surface	NOUN
admet-2338	233	11	of	of	ADP
admet-2338	233	12	the	the	DET
admet-2338	233	13	adsorbent	adsorbent	NOUN
admet-2338	233	14	getting	getting	AUX
admet-2338	233	15	dissolved	dissolve	VERB
admet-2338	233	16	leads	lead	NOUN
admet-2338	233	17	to	to	ADP
admet-2338	233	18	a	a	DET
admet-2338	233	19	decrease	decrease	NOUN
admet-2338	233	20	in	in	ADP
admet-2338	233	21	concentration	concentration	NOUN
admet-2338	233	22	.	.	PUNCT
admet-2338	234	1	however	however	ADV
admet-2338	234	2	,	,	PUNCT
admet-2338	234	3	pure	pure	ADJ
admet-2338	234	4	sfn	sfn	NOUN
admet-2338	234	5	tablets	tablet	NOUN
admet-2338	234	6	showed	show	VERB
admet-2338	234	7	<	<	X
admet-2338	234	8	30	30	NUM
admet-2338	234	9	%	%	NOUN
admet-2338	234	10	release	release	NOUN
admet-2338	234	11	in	in	ADP
admet-2338	234	12	1	1	NUM
admet-2338	234	13	hour	hour	NOUN
admet-2338	234	14	.	.	PUNCT
admet-2338	235	1	according	accord	VERB
admet-2338	235	2	to	to	ADP
admet-2338	235	3	the	the	DET
admet-2338	235	4	us	us	PROPN
admet-2338	235	5	fda	fda	PROPN
admet-2338	235	6	,	,	PUNCT
admet-2338	235	7	the	the	DET
admet-2338	235	8	dissolution	dissolution	NOUN
admet-2338	235	9	of	of	ADP
admet-2338	235	10	sfn	sfn	PROPN
admet-2338	235	11	formulations	formulation	NOUN
admet-2338	235	12	is	be	AUX
admet-2338	235	13	evaluated	evaluate	VERB
admet-2338	235	14	with	with	ADP
admet-2338	235	15	0.1	0.1	NUM
admet-2338	235	16	m	m	NOUN
admet-2338	235	17	hcl	hcl	NOUN
admet-2338	235	18	containing	contain	VERB
admet-2338	235	19	1	1	NUM
admet-2338	235	20	%	%	NOUN
admet-2338	235	21	sodium	sodium	NOUN
admet-2338	235	22	lauryl	lauryl	NOUN
admet-2338	235	23	sulphate	sulphate	NOUN
admet-2338	235	24	(	(	PUNCT
admet-2338	235	25	sls	sls	PROPN
admet-2338	235	26	)	)	PUNCT
admet-2338	236	1	[	[	X
admet-2338	236	2	40	40	NUM
admet-2338	236	3	]	]	PUNCT
admet-2338	236	4	.	.	PUNCT
admet-2338	237	1	in	in	ADP
admet-2338	237	2	this	this	DET
admet-2338	237	3	study	study	NOUN
admet-2338	237	4	,	,	PUNCT
admet-2338	237	5	1	1	NUM
admet-2338	237	6	%	%	NOUN
admet-2338	237	7	sls	sls	NOUN
admet-2338	237	8	was	be	AUX
admet-2338	237	9	not	not	PART
admet-2338	237	10	used	use	VERB
admet-2338	237	11	in	in	ADP
admet-2338	237	12	the	the	DET
admet-2338	237	13	dissolution	dissolution	NOUN
admet-2338	237	14	medium	medium	NOUN
admet-2338	237	15	because	because	SCONJ
admet-2338	237	16	our	our	PRON
admet-2338	237	17	major	major	ADJ
admet-2338	237	18	effort	effort	NOUN
admet-2338	237	19	was	be	AUX
admet-2338	237	20	to	to	PART
admet-2338	237	21	increase	increase	VERB
admet-2338	237	22	the	the	DET
admet-2338	237	23	aqueous	aqueous	ADJ
admet-2338	237	24	solubility	solubility	NOUN
admet-2338	237	25	and	and	CCONJ
admet-2338	237	26	dissolution	dissolution	NOUN
admet-2338	237	27	properties	property	NOUN
admet-2338	237	28	of	of	ADP
admet-2338	237	29	sfn	sfn	PROPN
admet-2338	237	30	using	use	VERB
admet-2338	237	31	surface	surface	NOUN
admet-2338	237	32	solid	solid	ADJ
admet-2338	237	33	dispersion	dispersion	NOUN
admet-2338	238	1	[	[	X
admet-2338	238	2	15,41	15,41	NOUN
admet-2338	238	3	]	]	PUNCT
admet-2338	238	4	.	.	PUNCT
admet-2338	239	1	figure	figure	NOUN
admet-2338	239	2	8	8	NUM
admet-2338	239	3	.	.	PUNCT
admet-2338	240	1	in	in	ADP
admet-2338	240	2	vitro	vitro	X
admet-2338	240	3	dissolution	dissolution	ADJ
admet-2338	240	4	profiles	profile	NOUN
admet-2338	240	5	of	of	ADP
admet-2338	240	6	sfn	sfn	PROPN
admet-2338	240	7	-	-	PUNCT
admet-2338	240	8	ssd	ssd	NOUN
admet-2338	240	9	and	and	CCONJ
admet-2338	240	10	pure	pure	ADJ
admet-2338	240	11	sfn	sfn	NOUN
admet-2338	240	12	tablets	tablet	NOUN
admet-2338	240	13	in	in	ADP
admet-2338	240	14	vivo	vivo	ADJ
admet-2338	240	15	pharmacokinetic	pharmacokinetic	ADJ
admet-2338	240	16	studies	study	NOUN
admet-2338	240	17	in	in	ADP
admet-2338	240	18	rats	rat	NOUN
admet-2338	240	19	the	the	DET
admet-2338	240	20	sfn	sfn	PROPN
admet-2338	240	21	-	-	PUNCT
admet-2338	240	22	ssd	ssd	NOUN
admet-2338	240	23	was	be	AUX
admet-2338	240	24	prepared	prepare	VERB
admet-2338	240	25	to	to	PART
admet-2338	240	26	improve	improve	VERB
admet-2338	240	27	the	the	DET
admet-2338	240	28	solubility	solubility	NOUN
admet-2338	240	29	and	and	CCONJ
admet-2338	240	30	bioavailability	bioavailability	NOUN
admet-2338	240	31	of	of	ADP
admet-2338	240	32	sfn	sfn	PROPN
admet-2338	240	33	.	.	PUNCT
admet-2338	241	1	the	the	DET
admet-2338	241	2	plasma	plasma	NOUN
admet-2338	241	3	levels	level	NOUN
admet-2338	241	4	after	after	ADP
admet-2338	241	5	oral	oral	ADJ
admet-2338	241	6	administration	administration	NOUN
admet-2338	241	7	of	of	ADP
admet-2338	241	8	sfn	sfn	PROPN
admet-2338	241	9	-	-	PUNCT
admet-2338	241	10	ssd	ssd	NOUN
admet-2338	241	11	were	be	AUX
admet-2338	241	12	compared	compare	VERB
admet-2338	241	13	with	with	ADP
admet-2338	241	14	pure	pure	ADJ
admet-2338	241	15	sfn	sfn	PROPN
admet-2338	241	16	.	.	PUNCT
admet-2338	242	1	the	the	DET
admet-2338	242	2	mean	mean	ADJ
admet-2338	242	3	plasma	plasma	NOUN
admet-2338	242	4	sfn	sfn	PROPN
admet-2338	242	5	concentration	concentration	NOUN
admet-2338	242	6	(	(	PUNCT
admet-2338	242	7	g	g	PROPN
admet-2338	242	8	/	/	SYM
admet-2338	242	9	ml	ml	NOUN
admet-2338	242	10	)	)	PUNCT
admet-2338	242	11	after	after	ADP
admet-2338	242	12	oral	oral	ADJ
admet-2338	242	13	administration	administration	NOUN
admet-2338	242	14	of	of	ADP
admet-2338	242	15	a	a	DET
admet-2338	242	16	single	single	ADJ
admet-2338	242	17	dose	dose	NOUN
admet-2338	242	18	of	of	ADP
admet-2338	242	19	the	the	DET
admet-2338	242	20	sfn	sfn	PROPN
admet-2338	242	21	-	-	PUNCT
admet-2338	242	22	ssd	ssd	NOUN
admet-2338	242	23	and	and	CCONJ
admet-2338	242	24	pure	pure	ADJ
admet-2338	242	25	sfn	sfn	NOUN
admet-2338	242	26	with	with	ADP
admet-2338	242	27	time	time	NOUN
admet-2338	242	28	(	(	PUNCT
admet-2338	242	29	h	h	NOUN
admet-2338	242	30	)	)	PUNCT
admet-2338	242	31	are	be	AUX
admet-2338	242	32	shown	show	VERB
admet-2338	242	33	in	in	ADP
admet-2338	242	34	figure	figure	NOUN
admet-2338	242	35	9	9	NUM
admet-2338	242	36	.	.	PUNCT
admet-2338	242	37	figure	figure	NOUN
admet-2338	242	38	9	9	NUM
admet-2338	242	39	.	.	PUNCT
admet-2338	243	1	plasma	plasma	NOUN
admet-2338	243	2	concentration	concentration	NOUN
admet-2338	243	3	-	-	PUNCT
admet-2338	243	4	time	time	NOUN
admet-2338	243	5	profiles	profile	NOUN
admet-2338	243	6	of	of	ADP
admet-2338	243	7	sfn	sfn	PROPN
admet-2338	243	8	from	from	ADP
admet-2338	243	9	sfn	sfn	PROPN
admet-2338	243	10	-	-	PUNCT
admet-2338	243	11	ssd	ssd	NOUN
admet-2338	243	12	and	and	CCONJ
admet-2338	243	13	pure	pure	ADJ
admet-2338	243	14	snf	snf	PROPN
admet-2338	243	15	in	in	ADP
admet-2338	243	16	rats	rat	NOUN
admet-2338	243	17	after	after	ADP
admet-2338	243	18	oral	oral	ADJ
admet-2338	243	19	administration	administration	NOUN
admet-2338	243	20	.	.	PUNCT
admet-2338	244	1	data	datum	NOUN
admet-2338	244	2	are	be	AUX
admet-2338	244	3	presented	present	VERB
admet-2338	244	4	as	as	ADP
admet-2338	244	5	the	the	DET
admet-2338	244	6	mean	mean	PROPN
admet-2338	244	7	±	±	NOUN
admet-2338	244	8	standard	standard	NOUN
admet-2338	244	9	error	error	NOUN
admet-2338	244	10	(	(	PUNCT
admet-2338	244	11	n=	n=	ADJ
admet-2338	244	12	3	3	NUM
admet-2338	244	13	)	)	PUNCT
admet-2338	244	14	the	the	DET
admet-2338	244	15	relevant	relevant	ADJ
admet-2338	244	16	pharmacokinetics	pharmacokinetic	NOUN
admet-2338	244	17	parameters	parameter	NOUN
admet-2338	244	18	derived	derive	VERB
admet-2338	244	19	by	by	ADP
admet-2338	244	20	noncompartmental	noncompartmental	ADJ
admet-2338	244	21	analysis	analysis	NOUN
admet-2338	244	22	are	be	AUX
admet-2338	244	23	given	give	VERB
admet-2338	244	24	in	in	ADP
admet-2338	244	25	table	table	NOUN
admet-2338	244	26	5	5	NUM
admet-2338	244	27	.	.	PUNCT
admet-2338	245	1	the	the	DET
admet-2338	245	2	sfn	sfn	PROPN
admet-2338	245	3	-	-	PUNCT
admet-2338	245	4	ssd	ssd	NOUN
admet-2338	245	5	showed	show	VERB
admet-2338	245	6	2and	2and	NUM
admet-2338	245	7	6.5	6.5	NUM
admet-2338	245	8	-	-	PUNCT
admet-2338	245	9	folds	fold	NOUN
admet-2338	245	10	improvement	improvement	NOUN
admet-2338	245	11	in	in	ADP
admet-2338	245	12	cmax	cmax	NOUN
admet-2338	245	13	(	(	PUNCT
admet-2338	245	14	p	p	X
admet-2338	245	15	<	<	X
admet-2338	245	16	0.01	0.01	NUM
admet-2338	245	17	)	)	PUNCT
admet-2338	245	18	and	and	CCONJ
admet-2338	245	19	auc0	auc0	PROPN
admet-2338	245	20	-	-	PUNCT
admet-2338	245	21	t	t	PROPN
admet-2338	245	22	as	as	ADP
admet-2338	245	23	compared	compare	VERB
admet-2338	245	24	to	to	ADP
admet-2338	245	25	pure	pure	ADJ
admet-2338	245	26	sfn	sfn	PROPN
admet-2338	245	27	due	due	ADP
admet-2338	245	28	to	to	ADP
admet-2338	245	29	faster	fast	ADJ
admet-2338	245	30	drug	drug	NOUN
admet-2338	245	31	release	release	NOUN
admet-2338	245	32	at	at	ADP
admet-2338	245	33	the	the	DET
admet-2338	245	34	site	site	NOUN
admet-2338	245	35	of	of	ADP
admet-2338	245	36	absorption	absorption	NOUN
admet-2338	245	37	from	from	ADP
admet-2338	245	38	the	the	DET
admet-2338	245	39	sfn	sfn	PROPN
admet-2338	245	40	-	-	PUNCT
admet-2338	245	41	ssd	ssd	NOUN
admet-2338	245	42	.	.	PUNCT
admet-2338	246	1	the	the	DET
admet-2338	246	2	improved	improved	ADJ
admet-2338	246	3	sfn	sfn	NOUN
admet-2338	246	4	concentration	concentration	NOUN
admet-2338	246	5	in	in	ADP
admet-2338	246	6	the	the	DET
admet-2338	246	7	blood	blood	NOUN
admet-2338	246	8	may	may	AUX
admet-2338	246	9	be	be	AUX
admet-2338	246	10	because	because	SCONJ
admet-2338	246	11	of	of	ADP
admet-2338	246	12	an	an	DET
admet-2338	246	13	enhancement	enhancement	NOUN
admet-2338	246	14	in	in	ADP
admet-2338	246	15	the	the	DET
admet-2338	246	16	aqueous	aqueous	ADJ
admet-2338	246	17	solubility	solubility	NOUN
admet-2338	246	18	of	of	ADP
admet-2338	246	19	sfn	sfn	PROPN
admet-2338	246	20	and	and	CCONJ
admet-2338	246	21	subsequent	subsequent	ADJ
admet-2338	246	22	absorption	absorption	NOUN
admet-2338	246	23	[	[	X
admet-2338	246	24	38,41	38,41	NUM
admet-2338	246	25	]	]	PUNCT
admet-2338	246	26	.	.	PUNCT
admet-2338	247	1	admet	admet	PROPN
admet-2338	247	2	&	&	CCONJ
admet-2338	247	3	dmpk	dmpk	PROPN
admet-2338	247	4	12(4	12(4	PROPN
admet-2338	247	5	)	)	PUNCT
admet-2338	247	6	(	(	PUNCT
admet-2338	247	7	2024	2024	NUM
admet-2338	247	8	)	)	PUNCT
admet-2338	247	9	687	687	NUM
admet-2338	247	10	-	-	SYM
admet-2338	247	11	702	702	NUM
admet-2338	247	12	neusilin	neusilin	PROPN
admet-2338	247	13	us2	us2	PROPN
admet-2338	247	14	based	base	VERB
admet-2338	247	15	surface	surface	NOUN
admet-2338	247	16	solid	solid	ADJ
admet-2338	247	17	dispersion	dispersion	NOUN
admet-2338	247	18	of	of	ADP
admet-2338	247	19	sorafenib	sorafenib	NOUN
admet-2338	247	20	tosylate	tosylate	VERB
admet-2338	247	21	doi	doi	NOUN
admet-2338	247	22	:	:	PUNCT
admet-2338	247	23	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	NOUN
admet-2338	247	24	699	699	NUM
admet-2338	247	25	table	table	NOUN
admet-2338	247	26	5	5	NUM
admet-2338	247	27	oral	oral	ADJ
admet-2338	247	28	pharmacokinetic	pharmacokinetic	ADJ
admet-2338	247	29	parameters	parameter	NOUN
admet-2338	247	30	of	of	ADP
admet-2338	247	31	sfn	sfn	PROPN
admet-2338	247	32	-	-	NOUN
admet-2338	247	33	sdd	sdd	NOUN
admet-2338	247	34	and	and	CCONJ
admet-2338	247	35	pure	pure	ADJ
admet-2338	247	36	sfn	sfn	NOUN
admet-2338	247	37	in	in	ADP
admet-2338	247	38	rats	rat	NOUN
admet-2338	247	39	parameters	parameter	NOUN
admet-2338	247	40	sfn	sfn	PROPN
admet-2338	247	41	sfn	sfn	PROPN
admet-2338	247	42	-	-	PUNCT
admet-2338	247	43	ssd	ssd	NOUN
admet-2338	247	44	cmax	cmax	NOUN
admet-2338	247	45	/	/	PUNCT
admet-2338	247	46	μg	μg	PROPN
admet-2338	247	47	ml-1	ml-1	ADV
admet-2338	247	48	1.318	1.318	NUM
admet-2338	247	49	±	±	NUM
admet-2338	247	50	0.186	0.186	NUM
admet-2338	247	51	2.655	2.655	NUM
admet-2338	247	52	±	±	NUM
admet-2338	247	53	0.406	0.406	NUM
admet-2338	247	54	*	*	PUNCT
admet-2338	247	55	tmax	tmax	PROPN
admet-2338	247	56	/	/	SYM
admet-2338	247	57	h	h	NOUN
admet-2338	247	58	4.661	4.661	NUM
admet-2338	247	59	±	±	NUM
admet-2338	247	60	1.155	1.155	NUM
admet-2338	247	61	3.0	3.0	NUM
admet-2338	247	62	±	±	NUM
admet-2338	247	63	0.0	0.0	NUM
admet-2338	247	64	auc	auc	NOUN
admet-2338	247	65	,	,	PUNCT
admet-2338	247	66	μg	μg	PROPN
admet-2338	247	67	ml-1	ml-1	ADV
admet-2338	247	68	9.381	9.381	NUM
admet-2338	247	69	±	±	NUM
admet-2338	248	1	4.966	4.966	NUM
admet-2338	248	2	59.686	59.686	NUM
admet-2338	248	3	±	±	NUM
admet-2338	248	4	7.858	7.858	NUM
admet-2338	248	5	*	*	PUNCT
admet-2338	248	6	kel	kel	PROPN
admet-2338	248	7	/	/	SYM
admet-2338	248	8	h-1	h-1	NOUN
admet-2338	248	9	0.0488	0.0488	NUM
admet-2338	248	10	±	±	NOUN
admet-2338	248	11	0.0120	0.0120	NUM
admet-2338	248	12	0.0336	0.0336	NUM
admet-2338	248	13	±	±	NUM
admet-2338	248	14	0.0075	0.0075	NUM
admet-2338	248	15	t1/2	t1/2	PROPN
admet-2338	248	16	/	/	SYM
admet-2338	248	17	h	h	NOUN
admet-2338	248	18	14.83	14.83	NUM
admet-2338	248	19	±	±	NUM
admet-2338	248	20	3.84	3.84	NUM
admet-2338	248	21	21.40	21.40	NUM
admet-2338	248	22	±	±	NUM
admet-2338	248	23	5.19	5.19	NUM
admet-2338	248	24	cl	cl	NOUN
admet-2338	248	25	f-1	f-1	NOUN
admet-2338	248	26	/	/	SYM
admet-2338	248	27	(	(	PUNCT
admet-2338	248	28	mg	mg	NOUN
admet-2338	248	29	/	/	SYM
admet-2338	248	30	h)/g	h)/g	PROPN
admet-2338	248	31	0.190	0.190	NUM
admet-2338	248	32	±	±	NUM
admet-2338	248	33	0.056	0.056	NUM
admet-2338	248	34	0.049	0.049	NUM
admet-2338	248	35	±	±	NUM
admet-2338	248	36	0.005	0.005	NUM
admet-2338	248	37	v	v	NOUN
admet-2338	248	38	f-1	f-1	NOUN
admet-2338	248	39	/	/	SYM
admet-2338	248	40	mg	mg	PROPN
admet-2338	248	41	(	(	PUNCT
admet-2338	248	42	μg	μg	NOUN
admet-2338	248	43	ml-1)-1	ml-1)-1	ADP
admet-2338	248	44	3.889	3.889	NUM
admet-2338	248	45	±	±	NUM
admet-2338	248	46	0.439	0.439	NUM
admet-2338	248	47	1.515	1.515	NUM
admet-2338	248	48	±	±	NUM
admet-2338	248	49	0.209	0.209	NUM
admet-2338	248	50	each	each	DET
admet-2338	248	51	value	value	NOUN
admet-2338	248	52	represents	represent	VERB
admet-2338	248	53	the	the	DET
admet-2338	248	54	mean	mean	ADJ
admet-2338	248	55	±	±	NOUN
admet-2338	248	56	standard	standard	ADJ
admet-2338	248	57	deviation	deviation	NOUN
admet-2338	248	58	(	(	PUNCT
admet-2338	248	59	n	n	NOUN
admet-2338	248	60	=	=	SYM
admet-2338	248	61	3	3	NUM
admet-2338	248	62	)	)	PUNCT
admet-2338	248	63	⁎p	⁎p	NOUN
admet-2338	248	64	<	<	X
admet-2338	248	65	0.05	0.05	NUM
admet-2338	248	66	;	;	PUNCT
admet-2338	248	67	cl	cl	NOUN
admet-2338	248	68	clearance	clearance	NOUN
admet-2338	248	69	rate	rate	NOUN
admet-2338	248	70	;	;	PUNCT
admet-2338	249	1	v	v	X
admet-2338	249	2	volume	volume	NOUN
admet-2338	249	3	of	of	ADP
admet-2338	249	4	distribution	distribution	NOUN
admet-2338	249	5	conclusion	conclusion	NOUN
admet-2338	249	6	this	this	DET
admet-2338	249	7	study	study	NOUN
admet-2338	249	8	demonstrates	demonstrate	VERB
admet-2338	249	9	the	the	DET
admet-2338	249	10	utility	utility	NOUN
admet-2338	249	11	of	of	ADP
admet-2338	249	12	ssd	ssd	NOUN
admet-2338	249	13	in	in	ADP
admet-2338	249	14	improving	improve	VERB
admet-2338	249	15	the	the	DET
admet-2338	249	16	biopharmaceutical	biopharmaceutical	ADJ
admet-2338	249	17	properties	property	NOUN
admet-2338	249	18	of	of	ADP
admet-2338	249	19	sfn	sfn	PROPN
admet-2338	249	20	.	.	PUNCT
admet-2338	250	1	the	the	DET
admet-2338	250	2	sfnssd	sfnssd	NOUN
admet-2338	250	3	was	be	AUX
admet-2338	250	4	successfully	successfully	ADV
admet-2338	250	5	prepared	prepare	VERB
admet-2338	250	6	using	use	VERB
admet-2338	250	7	a	a	DET
admet-2338	250	8	solvent	solvent	ADJ
admet-2338	250	9	evaporation	evaporation	NOUN
admet-2338	250	10	method	method	NOUN
admet-2338	250	11	with	with	ADP
admet-2338	250	12	nu2	nu2	PROPN
admet-2338	250	13	as	as	ADP
admet-2338	250	14	the	the	DET
admet-2338	250	15	adsorbent	adsorbent	NOUN
admet-2338	250	16	and	and	CCONJ
admet-2338	250	17	sds	sds	NOUN
admet-2338	250	18	as	as	ADP
admet-2338	250	19	the	the	DET
admet-2338	250	20	surfactant	surfactant	NOUN
admet-2338	250	21	and	and	CCONJ
admet-2338	250	22	optimized	optimize	VERB
admet-2338	250	23	using	use	VERB
admet-2338	250	24	design	design	NOUN
admet-2338	250	25	expert	expert	NOUN
admet-2338	250	26	11	11	NUM
admet-2338	250	27	.	.	PUNCT
admet-2338	251	1	the	the	DET
admet-2338	251	2	sfn	sfn	PROPN
admet-2338	251	3	-	-	PUNCT
admet-2338	251	4	ssd	ssd	NOUN
admet-2338	251	5	reflected	reflect	VERB
admet-2338	251	6	improved	improved	ADJ
admet-2338	251	7	oral	oral	ADJ
admet-2338	251	8	bioavailability	bioavailability	NOUN
admet-2338	251	9	compared	compare	VERB
admet-2338	251	10	to	to	ADP
admet-2338	251	11	the	the	DET
admet-2338	251	12	pure	pure	ADJ
admet-2338	251	13	form	form	NOUN
admet-2338	251	14	of	of	ADP
admet-2338	251	15	sfn	sfn	PROPN
admet-2338	251	16	due	due	ADP
admet-2338	251	17	to	to	ADP
admet-2338	251	18	faster	fast	ADJ
admet-2338	251	19	drug	drug	NOUN
admet-2338	251	20	release	release	NOUN
admet-2338	251	21	at	at	ADP
admet-2338	251	22	the	the	DET
admet-2338	251	23	absorption	absorption	NOUN
admet-2338	251	24	site	site	NOUN
admet-2338	251	25	.	.	PUNCT
admet-2338	252	1	the	the	DET
admet-2338	252	2	study	study	NOUN
admet-2338	252	3	concluded	conclude	VERB
admet-2338	252	4	that	that	SCONJ
admet-2338	252	5	ssd	ssd	NOUN
admet-2338	252	6	could	could	AUX
admet-2338	252	7	be	be	AUX
admet-2338	252	8	a	a	DET
admet-2338	252	9	scalable	scalable	ADJ
admet-2338	252	10	formulation	formulation	NOUN
admet-2338	252	11	approach	approach	NOUN
admet-2338	252	12	and	and	CCONJ
admet-2338	252	13	a	a	DET
admet-2338	252	14	more	more	ADV
admet-2338	252	15	industry	industry	NOUN
admet-2338	252	16	-	-	PUNCT
admet-2338	252	17	friendly	friendly	ADJ
admet-2338	252	18	technology	technology	NOUN
admet-2338	252	19	to	to	PART
admet-2338	252	20	improve	improve	VERB
admet-2338	252	21	the	the	DET
admet-2338	252	22	biopharmaceutical	biopharmaceutical	ADJ
admet-2338	252	23	properties	property	NOUN
admet-2338	252	24	of	of	ADP
admet-2338	252	25	sfn	sfn	PROPN
admet-2338	252	26	.	.	PUNCT
admet-2338	253	1	supplementary	supplementary	ADJ
admet-2338	253	2	material	material	PROPN
admet-2338	253	3	data	datum	NOUN
admet-2338	253	4	for	for	ADP
admet-2338	253	5	doe	doe	NOUN
admet-2338	253	6	formulation	formulation	NOUN
admet-2338	253	7	optimization	optimization	NOUN
admet-2338	253	8	are	be	AUX
admet-2338	253	9	available	available	ADJ
admet-2338	253	10	electronically	electronically	ADV
admet-2338	253	11	on	on	ADP
admet-2338	253	12	the	the	DET
admet-2338	253	13	journal	journal	NOUN
admet-2338	253	14	's	's	PART
admet-2338	253	15	website	website	NOUN
admet-2338	253	16	page	page	NOUN
admet-2338	253	17	:	:	PUNCT
admet-2338	253	18	https://pub.iapchem.org/ojs/index.php/admet/article/view/2338	https://pub.iapchem.org/ojs/index.php/admet/article/view/2338	NOUN
admet-2338	253	19	,	,	PUNCT
admet-2338	253	20	or	or	CCONJ
admet-2338	253	21	from	from	ADP
admet-2338	253	22	the	the	DET
admet-2338	253	23	corresponding	corresponding	ADJ
admet-2338	253	24	author	author	NOUN
admet-2338	253	25	upon	upon	SCONJ
admet-2338	253	26	request	request	NOUN
admet-2338	253	27	.	.	PUNCT
admet-2338	254	1	list	list	NOUN
admet-2338	254	2	of	of	ADP
admet-2338	254	3	abbreviations	abbreviation	NOUN
admet-2338	254	4	dmso	dmso	NOUN
admet-2338	254	5	:	:	PUNCT
admet-2338	254	6	dimethyl	dimethyl	NOUN
admet-2338	254	7	sulfoxide	sulfoxide	NOUN
admet-2338	254	8	ddw	ddw	PROPN
admet-2338	254	9	:	:	PUNCT
admet-2338	254	10	double	double	ADJ
admet-2338	254	11	distilled	distil	VERB
admet-2338	254	12	water	water	NOUN
admet-2338	254	13	dsc	dsc	PROPN
admet-2338	254	14	:	:	PUNCT
admet-2338	254	15	differential	differential	NOUN
admet-2338	254	16	scanning	scan	VERB
admet-2338	254	17	calorimetry	calorimetry	NOUN
admet-2338	254	18	doe	doe	NOUN
admet-2338	254	19	:	:	PUNCT
admet-2338	254	20	design	design	NOUN
admet-2338	254	21	of	of	ADP
admet-2338	254	22	experiment	experiment	NOUN
admet-2338	254	23	ftir	ftir	NOUN
admet-2338	254	24	:	:	PUNCT
admet-2338	254	25	fourier	fourier	NOUN
admet-2338	254	26	transform	transform	NOUN
admet-2338	254	27	-	-	PUNCT
admet-2338	254	28	infrared	infrared	ADJ
admet-2338	254	29	spectroscopy	spectroscopy	NOUN
admet-2338	254	30	,	,	PUNCT
admet-2338	254	31	ipa	ipa	PROPN
admet-2338	254	32	:	:	PUNCT
admet-2338	254	33	isopropyl	isopropyl	NOUN
admet-2338	254	34	alcohol	alcohol	NOUN
admet-2338	254	35	ip	ip	NOUN
admet-2338	254	36	:	:	PUNCT
admet-2338	254	37	indian	indian	ADJ
admet-2338	254	38	pharmacopoeia	pharmacopoeia	NOUN
admet-2338	254	39	mas	mas	PROPN
admet-2338	254	40	:	:	PUNCT
admet-2338	254	41	magnesium	magnesium	NOUN
admet-2338	254	42	aluminometasilicate	aluminometasilicate	ADJ
admet-2338	254	43	pdgfr	pdgfr	NOUN
admet-2338	254	44	:	:	PUNCT
admet-2338	254	45	platelet	platelet	ADJ
admet-2338	254	46	-	-	PUNCT
admet-2338	254	47	derived	derive	VERB
admet-2338	254	48	growth	growth	NOUN
admet-2338	254	49	factor	factor	NOUN
admet-2338	254	50	receptor	receptor	NOUN
admet-2338	254	51	pxrd	pxrd	PROPN
admet-2338	254	52	:	:	PUNCT
admet-2338	254	53	powder	powder	NOUN
admet-2338	254	54	x	x	NOUN
admet-2338	254	55	-	-	NOUN
admet-2338	254	56	ray	ray	NOUN
admet-2338	254	57	powder	powder	NOUN
admet-2338	254	58	diffraction	diffraction	NOUN
admet-2338	254	59	sem	sem	NOUN
admet-2338	254	60	:	:	PUNCT
admet-2338	254	61	scanning	scan	VERB
admet-2338	254	62	electronic	electronic	ADJ
admet-2338	254	63	microscopy	microscopy	NOUN
admet-2338	254	64	sfn	sfn	NOUN
admet-2338	254	65	:	:	PUNCT
admet-2338	254	66	sorafenib	sorafenib	PROPN
admet-2338	254	67	tosylate	tosylate	VERB
admet-2338	254	68	ssd	ssd	PROPN
admet-2338	254	69	:	:	PUNCT
admet-2338	254	70	surface	surface	NOUN
admet-2338	254	71	solid	solid	ADJ
admet-2338	254	72	dispersion	dispersion	NOUN
admet-2338	254	73	sds	sds	NOUN
admet-2338	254	74	:	:	PUNCT
admet-2338	254	75	sodium	sodium	NOUN
admet-2338	254	76	dodecyl	dodecyl	PROPN
admet-2338	254	77	sulphate	sulphate	NOUN
admet-2338	254	78	vegfr	vegfr	NOUN
admet-2338	254	79	:	:	PUNCT
admet-2338	254	80	vascular	vascular	ADJ
admet-2338	254	81	endothelial	endothelial	ADJ
admet-2338	254	82	growth	growth	NOUN
admet-2338	254	83	factor	factor	NOUN
admet-2338	254	84	receptor	receptor	NOUN
admet-2338	254	85	ethics	ethic	NOUN
admet-2338	254	86	approval	approval	NOUN
admet-2338	254	87	and	and	CCONJ
admet-2338	254	88	consent	consent	NOUN
admet-2338	254	89	to	to	PART
admet-2338	254	90	participate	participate	VERB
admet-2338	254	91	:	:	PUNCT
admet-2338	254	92	animal	animal	NOUN
admet-2338	254	93	experimentation	experimentation	NOUN
admet-2338	254	94	procedures	procedure	NOUN
admet-2338	254	95	were	be	AUX
admet-2338	254	96	followed	follow	VERB
admet-2338	254	97	in	in	ADP
admet-2338	254	98	accordance	accordance	NOUN
admet-2338	254	99	with	with	ADP
admet-2338	254	100	cpcsea	cpcsea	PROPN
admet-2338	254	101	guideline	guideline	NOUN
admet-2338	254	102	.	.	PUNCT
admet-2338	255	1	human	human	ADJ
admet-2338	255	2	and	and	CCONJ
admet-2338	255	3	animal	animal	NOUN
admet-2338	255	4	rights	right	NOUN
admet-2338	255	5	:	:	PUNCT
admet-2338	255	6	the	the	DET
admet-2338	255	7	protocol	protocol	NOUN
admet-2338	255	8	of	of	ADP
admet-2338	255	9	experimentation	experimentation	NOUN
admet-2338	255	10	on	on	ADP
admet-2338	255	11	the	the	DET
admet-2338	255	12	animal	animal	NOUN
admet-2338	255	13	was	be	AUX
admet-2338	255	14	approved	approve	VERB
admet-2338	255	15	(	(	PUNCT
admet-2338	255	16	cpcsea	cpcsea	ADJ
admet-2338	255	17	number	number	NOUN
admet-2338	255	18	:	:	PUNCT
admet-2338	255	19	cpcsea	cpcsea	NOUN
admet-2338	255	20	/	/	SYM
admet-2338	255	21	pcp	pcp	PROPN
admet-2338	255	22	/	/	SYM
admet-2338	255	23	pct12/2018	pct12/2018	NOUN
admet-2338	255	24	)	)	PUNCT
admet-2338	255	25	from	from	ADP
admet-2338	255	26	the	the	DET
admet-2338	255	27	institutional	institutional	ADJ
admet-2338	255	28	animal	animal	NOUN
admet-2338	255	29	ethical	ethical	PROPN
admet-2338	255	30	committee	committee	NOUN
admet-2338	255	31	(	(	PUNCT
admet-2338	255	32	iaec	iaec	NOUN
admet-2338	255	33	)	)	PUNCT
admet-2338	255	34	registration	registration	NOUN
admet-2338	255	35	no	no	NOUN
admet-2338	255	36	.	.	NOUN
admet-2338	256	1	1703	1703	NUM
admet-2338	256	2	/	/	SYM
admet-2338	256	3	po	po	NOUN
admet-2338	256	4	/	/	SYM
admet-2338	256	5	re	re	ADJ
admet-2338	256	6	/	/	SYM
admet-2338	256	7	s/01	s/01	ADJ
admet-2338	256	8	/	/	SYM
admet-2338	256	9	cpcsea	cpcsea	NOUN
admet-2338	256	10	.	.	PUNCT
admet-2338	257	1	consent	consent	NOUN
admet-2338	257	2	for	for	ADP
admet-2338	257	3	publication	publication	NOUN
admet-2338	257	4	:	:	PUNCT
admet-2338	257	5	not	not	PART
admet-2338	257	6	applicable	applicable	ADJ
admet-2338	257	7	.	.	PUNCT
admet-2338	258	1	conflict	conflict	NOUN
admet-2338	258	2	of	of	ADP
admet-2338	258	3	interest	interest	NOUN
admet-2338	258	4	:	:	PUNCT
admet-2338	258	5	the	the	DET
admet-2338	258	6	authors	author	NOUN
admet-2338	258	7	declare	declare	VERB
admet-2338	258	8	no	no	DET
admet-2338	258	9	conflict	conflict	NOUN
admet-2338	258	10	of	of	ADP
admet-2338	258	11	interest	interest	NOUN
admet-2338	258	12	,	,	PUNCT
admet-2338	258	13	financial	financial	ADJ
admet-2338	258	14	or	or	CCONJ
admet-2338	258	15	otherwise	otherwise	ADV
admet-2338	258	16	.	.	PUNCT
admet-2338	259	1	data	datum	NOUN
admet-2338	259	2	availability	availability	NOUN
admet-2338	259	3	:	:	PUNCT
admet-2338	259	4	the	the	DET
admet-2338	259	5	data	datum	NOUN
admet-2338	259	6	used	use	VERB
admet-2338	259	7	to	to	PART
admet-2338	259	8	support	support	VERB
admet-2338	259	9	the	the	DET
admet-2338	259	10	study	study	NOUN
admet-2338	259	11	are	be	AUX
admet-2338	259	12	available	available	ADJ
admet-2338	259	13	from	from	ADP
admet-2338	259	14	the	the	DET
admet-2338	259	15	corresponding	correspond	VERB
admet-2338	259	16	authors	author	NOUN
admet-2338	259	17	on	on	ADP
admet-2338	259	18	request	request	NOUN
admet-2338	259	19	.	.	PUNCT
admet-2338	260	1	funding	funding	NOUN
admet-2338	260	2	:	:	PUNCT
admet-2338	260	3	bharati	bharati	PROPN
admet-2338	260	4	vidyapeeth	vidyapeeth	PROPN
admet-2338	260	5	(	(	PUNCT
admet-2338	260	6	deemed	deem	VERB
admet-2338	260	7	to	to	PART
admet-2338	260	8	be	be	AUX
admet-2338	260	9	a	a	DET
admet-2338	260	10	university	university	NOUN
admet-2338	260	11	)	)	PUNCT
admet-2338	260	12	was	be	AUX
admet-2338	260	13	the	the	DET
admet-2338	260	14	source	source	NOUN
admet-2338	260	15	of	of	ADP
admet-2338	260	16	funding	funding	NOUN
admet-2338	260	17	for	for	ADP
admet-2338	260	18	the	the	DET
admet-2338	260	19	successful	successful	ADJ
admet-2338	260	20	completion	completion	NOUN
admet-2338	260	21	of	of	ADP
admet-2338	260	22	the	the	DET
admet-2338	260	23	project	project	NOUN
admet-2338	260	24	.	.	PUNCT
admet-2338	261	1	https://doi.org/10.5599/admet.2338	https://doi.org/10.5599/admet.2338	PROPN
admet-2338	261	2	https://pub.iapchem.org/ojs/index.php/admet/article/view/2338	https://pub.iapchem.org/ojs/index.php/admet/article/view/2338	X
admet-2338	261	3	b.	b.	PROPN
admet-2338	261	4	kumar	kumar	PROPN
admet-2338	261	5	panda	panda	PROPN
admet-2338	261	6	et	et	PROPN
admet-2338	261	7	al	al	PROPN
admet-2338	261	8	.	.	PROPN
admet-2338	261	9	admet	admet	PROPN
admet-2338	261	10	&	&	CCONJ
admet-2338	261	11	dmpk	dmpk	PROPN
admet-2338	261	12	12(4	12(4	PROPN
admet-2338	261	13	)	)	PUNCT
admet-2338	261	14	(	(	PUNCT
admet-2338	261	15	2024	2024	NUM
admet-2338	261	16	)	)	PUNCT
admet-2338	261	17	687	687	NUM
admet-2338	261	18	-	-	SYM
admet-2338	261	19	702	702	NUM
admet-2338	261	20	700	700	NUM
admet-2338	261	21	acknowledgements	acknowledgement	NOUN
admet-2338	261	22	:	:	PUNCT
admet-2338	261	23	the	the	DET
admet-2338	261	24	authors	author	NOUN
admet-2338	261	25	gratefully	gratefully	ADV
admet-2338	261	26	acknowledge	acknowledge	VERB
admet-2338	261	27	cipla	cipla	PROPN
admet-2338	261	28	ltd	ltd	PROPN
admet-2338	261	29	,	,	PUNCT
admet-2338	261	30	mumbai	mumbai	PROPN
admet-2338	261	31	,	,	PUNCT
admet-2338	261	32	for	for	ADP
admet-2338	261	33	providing	provide	VERB
admet-2338	261	34	a	a	DET
admet-2338	261	35	gift	gift	NOUN
admet-2338	261	36	sample	sample	NOUN
admet-2338	261	37	of	of	ADP
admet-2338	261	38	sfn	sfn	PROPN
admet-2338	261	39	.	.	PUNCT
admet-2338	262	1	the	the	DET
admet-2338	262	2	authors	author	NOUN
admet-2338	262	3	would	would	AUX
admet-2338	262	4	like	like	VERB
admet-2338	262	5	to	to	PART
admet-2338	262	6	acknowledge	acknowledge	VERB
admet-2338	262	7	aicte	aicte	PROPN
admet-2338	262	8	,	,	PUNCT
admet-2338	262	9	india	india	PROPN
admet-2338	262	10	,	,	PUNCT
admet-2338	262	11	for	for	ADP
admet-2338	262	12	providing	provide	VERB
admet-2338	262	13	gpat	gpat	NOUN
admet-2338	262	14	scholarship	scholarship	NOUN
admet-2338	262	15	.	.	PUNCT
admet-2338	263	1	references	reference	NOUN
admet-2338	263	2	[	[	X
admet-2338	263	3	1	1	NUM
admet-2338	263	4	]	]	X
admet-2338	263	5	h.b	h.b	PROPN
admet-2338	263	6	.	.	PROPN
admet-2338	263	7	el	el	PROPN
admet-2338	263	8	-	-	PUNCT
admet-2338	263	9	serag	serag	NOUN
admet-2338	263	10	,	,	PUNCT
admet-2338	263	11	m.	m.	NOUN
admet-2338	263	12	margaret	margaret	PROPN
admet-2338	263	13	,	,	PUNCT
admet-2338	263	14	ab	ab	PROPN
admet-2338	263	15	.	.	PROPN
admet-2338	263	16	alkek	alkek	PROPN
admet-2338	263	17	.	.	PUNCT
admet-2338	264	1	current	current	ADJ
admet-2338	264	2	status	status	NOUN
admet-2338	264	3	of	of	ADP
admet-2338	264	4	sorafenib	sorafenib	NOUN
admet-2338	264	5	use	use	VERB
admet-2338	264	6	for	for	ADP
admet-2338	264	7	treatment	treatment	NOUN
admet-2338	264	8	of	of	ADP
admet-2338	264	9	hepatocellular	hepatocellular	ADJ
admet-2338	264	10	carcinoma	carcinoma	NOUN
admet-2338	264	11	.	.	PUNCT
admet-2338	265	1	gastroenterology	gastroenterology	NOUN
admet-2338	265	2	&	&	CCONJ
admet-2338	265	3	hepatology	hepatology	NOUN
admet-2338	265	4	(	(	PUNCT
admet-2338	265	5	n	n	CCONJ
admet-2338	265	6	y	y	NOUN
admet-2338	265	7	)	)	PUNCT
admet-2338	265	8	13(10	13(10	NUM
admet-2338	265	9	)	)	PUNCT
admet-2338	265	10	(	(	PUNCT
admet-2338	265	11	2017	2017	NUM
admet-2338	265	12	)	)	PUNCT
admet-2338	265	13	623	623	NUM
admet-2338	265	14	-	-	SYM
admet-2338	265	15	625	625	NUM
admet-2338	265	16	.	.	PUNCT
admet-2338	266	1	https://pubmed.ncbi.nlm.nih.gov/29230141	https://pubmed.ncbi.nlm.nih.gov/29230141	PROPN
admet-2338	266	2	[	[	X
admet-2338	266	3	2	2	NUM
admet-2338	266	4	]	]	X
admet-2338	266	5	r	r	NOUN
admet-2338	266	6	iyer	iyer	NOUN
admet-2338	266	7	,	,	PUNCT
admet-2338	266	8	g	g	PROPN
admet-2338	266	9	fetterly	fetterly	NOUN
admet-2338	266	10	,	,	PUNCT
admet-2338	266	11	a	a	DET
admet-2338	266	12	lugade	lugade	NOUN
admet-2338	266	13	,	,	PUNCT
admet-2338	266	14	y	y	PROPN
admet-2338	266	15	thanavala	thanavala	PROPN
admet-2338	266	16	.	.	PUNCT
admet-2338	267	1	sorafenib	sorafenib	PROPN
admet-2338	267	2	:	:	PUNCT
admet-2338	267	3	a	a	DET
admet-2338	267	4	clinical	clinical	ADJ
admet-2338	267	5	and	and	CCONJ
admet-2338	267	6	pharmacologic	pharmacologic	ADJ
admet-2338	267	7	review	review	NOUN
admet-2338	267	8	.	.	PUNCT
admet-2338	268	1	expert	expert	ADJ
admet-2338	268	2	opinion	opinion	NOUN
admet-2338	268	3	on	on	ADP
admet-2338	268	4	pharmacotherapy	pharmacotherapy	NOUN
admet-2338	268	5	11	11	NUM
admet-2338	268	6	(	(	PUNCT
admet-2338	268	7	2010	2010	NUM
admet-2338	268	8	)	)	PUNCT
admet-2338	268	9	1943	1943	NUM
admet-2338	268	10	-	-	SYM
admet-2338	268	11	1955	1955	NUM
admet-2338	268	12	.	.	PUNCT
admet-2338	268	13	https://doi.org/10.1517/14656566.2010.496453	https://doi.org/10.1517/14656566.2010.496453	PUNCT
admet-2338	269	1	[	[	X
admet-2338	269	2	3	3	NUM
admet-2338	269	3	]	]	X
admet-2338	269	4	g	g	NOUN
admet-2338	269	5	marisi	marisi	X
admet-2338	269	6	,	,	PUNCT
admet-2338	269	7	a	a	DET
admet-2338	269	8	cucchetti	cucchetti	NOUN
admet-2338	269	9	,	,	PUNCT
admet-2338	269	10	p	p	NOUN
admet-2338	269	11	ulivi	ulivi	NOUN
admet-2338	269	12	,	,	PUNCT
admet-2338	269	13	m	m	VERB
admet-2338	269	14	canale	canale	ADJ
admet-2338	269	15	,	,	PUNCT
admet-2338	269	16	g	g	PROPN
admet-2338	269	17	cabibbo	cabibbo	NOUN
admet-2338	269	18	,	,	PUNCT
admet-2338	269	19	l	l	NOUN
admet-2338	269	20	solaini	solaini	PROPN
admet-2338	269	21	,	,	PUNCT
admet-2338	269	22	f.g	f.g	NOUN
admet-2338	269	23	.	.	PROPN
admet-2338	269	24	foschi	foschi	PROPN
admet-2338	269	25	,	,	PUNCT
admet-2338	269	26	d.e	d.e	PROPN
admet-2338	269	27	.	.	PROPN
admet-2338	269	28	matteis	matteis	PROPN
admet-2338	269	29	,	,	PUNCT
admet-2338	269	30	g	g	PROPN
admet-2338	269	31	ercolani	ercolani	PROPN
admet-2338	269	32	,	,	PUNCT
admet-2338	269	33	m	m	NOUN
admet-2338	269	34	valgiusti	valgiusti	NOUN
admet-2338	269	35	,	,	PUNCT
admet-2338	269	36	g.l	g.l	PROPN
admet-2338	269	37	.	.	PROPN
admet-2338	269	38	frassineti	frassineti	PROPN
admet-2338	269	39	,	,	PUNCT
admet-2338	269	40	m.	m.	NOUN
admet-2338	269	41	scartozzi	scartozzi	NOUN
admet-2338	269	42	,	,	PUNCT
admet-2338	269	43	g.a	g.a	PROPN
admet-2338	269	44	.	.	PROPN
admet-2338	269	45	casadei	casadei	PROPN
admet-2338	269	46	.	.	PUNCT
admet-2338	270	1	ten	ten	NUM
admet-2338	270	2	years	year	NOUN
admet-2338	270	3	of	of	ADP
admet-2338	270	4	sorafenib	sorafenib	NOUN
admet-2338	270	5	in	in	ADP
admet-2338	270	6	hepatocellular	hepatocellular	ADJ
admet-2338	270	7	carcinoma	carcinoma	NOUN
admet-2338	270	8	:	:	PUNCT
admet-2338	270	9	are	be	AUX
admet-2338	270	10	there	there	PRON
admet-2338	270	11	any	any	DET
admet-2338	270	12	predictive	predictive	ADJ
admet-2338	270	13	and/or	and/or	CCONJ
admet-2338	270	14	prognostic	prognostic	ADJ
admet-2338	270	15	markers	marker	NOUN
admet-2338	270	16	?	?	PUNCT
admet-2338	271	1	world	world	PROPN
admet-2338	271	2	journal	journal	PROPN
admet-2338	271	3	of	of	ADP
admet-2338	271	4	gastroenterology	gastroenterology	NOUN
admet-2338	271	5	36	36	NUM
admet-2338	271	6	(	(	PUNCT
admet-2338	271	7	2018	2018	NUM
admet-2338	271	8	)	)	PUNCT
admet-2338	271	9	4152	4152	NUM
admet-2338	271	10	-	-	SYM
admet-2338	271	11	4163	4163	NUM
admet-2338	271	12	.	.	PUNCT
admet-2338	272	1	https://doi.org/10.3748/wjg.v24.i36.4152	https://doi.org/10.3748/wjg.v24.i36.4152	NOUN
admet-2338	273	1	[	[	X
admet-2338	273	2	4	4	NUM
admet-2338	273	3	]	]	X
admet-2338	273	4	d.h	d.h	PROPN
admet-2338	273	5	.	.	PROPN
admet-2338	273	6	truong	truong	PROPN
admet-2338	273	7	,	,	PUNCT
admet-2338	273	8	t.h	t.h	PROPN
admet-2338	273	9	.	.	PROPN
admet-2338	273	10	tran	tran	PROPN
admet-2338	273	11	,	,	PUNCT
admet-2338	273	12	t.	t.	PROPN
admet-2338	273	13	ramasamy	ramasamy	PROPN
admet-2338	273	14	,	,	PUNCT
admet-2338	273	15	j.y	j.y	PROPN
admet-2338	273	16	.	.	PROPN
admet-2338	273	17	choi	choi	PROPN
admet-2338	273	18	,	,	PUNCT
admet-2338	273	19	h.g	h.g	PROPN
admet-2338	273	20	.	.	PROPN
admet-2338	273	21	choi	choi	PROPN
admet-2338	273	22	,	,	PUNCT
admet-2338	273	23	c.s	c.s	PROPN
admet-2338	273	24	.	.	PROPN
admet-2338	273	25	yong	yong	PROPN
admet-2338	273	26	.	.	PUNCT
admet-2338	274	1	preparation	preparation	NOUN
admet-2338	274	2	and	and	CCONJ
admet-2338	274	3	characterization	characterization	NOUN
admet-2338	274	4	of	of	ADP
admet-2338	274	5	solid	solid	ADJ
admet-2338	274	6	dispersion	dispersion	NOUN
admet-2338	274	7	using	use	VERB
admet-2338	274	8	a	a	DET
admet-2338	274	9	novel	novel	ADJ
admet-2338	274	10	amphiphilic	amphiphilic	ADJ
admet-2338	274	11	copolymer	copolymer	NOUN
admet-2338	274	12	to	to	PART
admet-2338	274	13	enhance	enhance	VERB
admet-2338	274	14	dissolution	dissolution	NOUN
admet-2338	274	15	and	and	CCONJ
admet-2338	274	16	oral	oral	ADJ
admet-2338	274	17	bioavailability	bioavailability	NOUN
admet-2338	274	18	of	of	ADP
admet-2338	274	19	sorafenib	sorafenib	NOUN
admet-2338	274	20	.	.	PUNCT
admet-2338	275	1	powder	powder	NOUN
admet-2338	275	2	technology	technology	NOUN
admet-2338	275	3	283	283	NUM
admet-2338	275	4	(	(	PUNCT
admet-2338	275	5	2015	2015	NUM
admet-2338	275	6	)	)	PUNCT
admet-2338	275	7	260	260	NUM
admet-2338	275	8	-	-	SYM
admet-2338	275	9	265	265	NUM
admet-2338	275	10	.	.	PUNCT
admet-2338	276	1	https://doi.org/10.1016/j.powtec.2015.04.044	https://doi.org/10.1016/j.powtec.2015.04.044	X
admet-2338	277	1	[	[	X
admet-2338	277	2	5	5	NUM
admet-2338	277	3	]	]	PUNCT
admet-2338	277	4	a.	a.	NOUN
admet-2338	277	5	pawar	pawar	PROPN
admet-2338	277	6	,	,	PUNCT
admet-2338	277	7	c.	c.	PROPN
admet-2338	277	8	bothiraja	bothiraja	PROPN
admet-2338	277	9	,	,	PUNCT
admet-2338	277	10	k.	k.	PROPN
admet-2338	277	11	shaikh	shaikh	PROPN
admet-2338	277	12	,	,	PUNCT
admet-2338	277	13	a.	a.	PROPN
admet-2338	277	14	mali	mali	PROPN
admet-2338	277	15	.	.	PUNCT
admet-2338	278	1	an	an	DET
admet-2338	278	2	insight	insight	NOUN
admet-2338	278	3	into	into	ADP
admet-2338	278	4	cochleates	cochleate	NOUN
admet-2338	278	5	,	,	PUNCT
admet-2338	278	6	a	a	DET
admet-2338	278	7	potential	potential	ADJ
admet-2338	278	8	drug	drug	NOUN
admet-2338	278	9	delivery	delivery	NOUN
admet-2338	278	10	system	system	NOUN
admet-2338	278	11	.	.	PUNCT
admet-2338	279	1	rsc	rsc	PROPN
admet-2338	279	2	advances	advance	VERB
admet-2338	279	3	5	5	NUM
admet-2338	279	4	(	(	PUNCT
admet-2338	279	5	2015	2015	NUM
admet-2338	279	6	)	)	PUNCT
admet-2338	279	7	81188	81188	NUM
admet-2338	279	8	-	-	SYM
admet-2338	279	9	81202	81202	NUM
admet-2338	279	10	.	.	PUNCT
admet-2338	280	1	https://doi.org/10.1039/c5ra08550k	https://doi.org/10.1039/c5ra08550k	PROPN
admet-2338	281	1	[	[	X
admet-2338	281	2	6	6	NUM
admet-2338	281	3	]	]	PUNCT
admet-2338	281	4	c.	c.	PROPN
admet-2338	281	5	bothiraja	bothiraja	PROPN
admet-2338	281	6	,	,	PUNCT
admet-2338	281	7	a.p	a.p	PROPN
admet-2338	281	8	.	.	PROPN
admet-2338	281	9	pawar	pawar	PROPN
admet-2338	281	10	,	,	PUNCT
admet-2338	281	11	a.j	a.j	PROPN
admet-2338	281	12	.	.	PROPN
admet-2338	281	13	mali	mali	PROPN
admet-2338	281	14	,	,	PUNCT
admet-2338	281	15	k.s	k.s	PROPN
admet-2338	281	16	.	.	PROPN
admet-2338	281	17	shaikh	shaikh	PROPN
admet-2338	281	18	.	.	PUNCT
admet-2338	282	1	improved	improve	VERB
admet-2338	282	2	pharmaceutical	pharmaceutical	ADJ
admet-2338	282	3	properties	property	NOUN
admet-2338	282	4	of	of	ADP
admet-2338	282	5	surface	surface	NOUN
admet-2338	282	6	modified	modify	VERB
admet-2338	282	7	bioactive	bioactive	PROPN
admet-2338	282	8	plumbagin	plumbagin	NOUN
admet-2338	282	9	crystals	crystal	NOUN
admet-2338	282	10	.	.	PUNCT
admet-2338	283	1	international	international	ADJ
admet-2338	283	2	journal	journal	PROPN
admet-2338	283	3	of	of	ADP
admet-2338	283	4	surface	surface	NOUN
admet-2338	283	5	science	science	NOUN
admet-2338	283	6	and	and	CCONJ
admet-2338	283	7	engineering	engineering	NOUN
admet-2338	283	8	7	7	NUM
admet-2338	283	9	(	(	PUNCT
admet-2338	283	10	2013	2013	NUM
admet-2338	283	11	)	)	PUNCT
admet-2338	283	12	181	181	NUM
admet-2338	283	13	.	.	PUNCT
admet-2338	284	1	https://doi.org/10.1504/ijsurfse.2013.053708	https://doi.org/10.1504/ijsurfse.2013.053708	PROPN
admet-2338	285	1	[	[	X
admet-2338	285	2	7	7	X
admet-2338	285	3	]	]	X
admet-2338	285	4	k.m	k.m	PROPN
admet-2338	285	5	.	.	PROPN
admet-2338	285	6	pantalone	pantalone	NOUN
admet-2338	285	7	,	,	PUNCT
admet-2338	285	8	t.	t.	PROPN
admet-2338	285	9	gopan	gopan	PROPN
admet-2338	285	10	,	,	PUNCT
admet-2338	285	11	e.m	e.m	PROPN
admet-2338	285	12	.	.	PROPN
admet-2338	285	13	remer	remer	PROPN
admet-2338	285	14	,	,	PUNCT
admet-2338	285	15	c.	c.	PROPN
admet-2338	285	16	faiman	faiman	NOUN
admet-2338	285	17	,	,	PUNCT
admet-2338	285	18	a.g	a.g	PROPN
admet-2338	285	19	.	.	PROPN
admet-2338	285	20	loachimescu	loachimescu	PROPN
admet-2338	285	21	,	,	PUNCT
admet-2338	286	1	h.s	h.s	PROPN
admet-2338	286	2	.	.	PROPN
admet-2338	286	3	levin	levin	PROPN
admet-2338	286	4	.	.	PUNCT
admet-2338	287	1	change	change	NOUN
admet-2338	287	2	in	in	ADP
admet-2338	287	3	adrenal	adrenal	ADJ
admet-2338	287	4	mass	mass	NOUN
admet-2338	287	5	size	size	NOUN
admet-2338	287	6	as	as	ADP
admet-2338	287	7	a	a	DET
admet-2338	287	8	predictor	predictor	NOUN
admet-2338	287	9	of	of	ADP
admet-2338	287	10	a	a	DET
admet-2338	287	11	malignant	malignant	ADJ
admet-2338	287	12	tumor	tumor	NOUN
admet-2338	287	13	.	.	PUNCT
admet-2338	288	1	endocrine	endocrine	ADJ
admet-2338	288	2	practice	practice	NOUN
admet-2338	288	3	16	16	NUM
admet-2338	288	4	(	(	PUNCT
admet-2338	288	5	2010	2010	NUM
admet-2338	288	6	)	)	PUNCT
admet-2338	288	7	577	577	NUM
admet-2338	288	8	-	-	SYM
admet-2338	288	9	587	587	NUM
admet-2338	288	10	.	.	PUNCT
admet-2338	289	1	https://doi.org/10.4158/ep09351.or	https://doi.org/10.4158/ep09351.or	PROPN
admet-2338	289	2	[	[	X
admet-2338	289	3	8	8	NUM
admet-2338	289	4	]	]	X
admet-2338	289	5	r.k	r.k	PROPN
admet-2338	289	6	.	.	PROPN
admet-2338	289	7	ameta	ameta	PROPN
admet-2338	289	8	,	,	PUNCT
admet-2338	289	9	k.	k.	PROPN
admet-2338	289	10	soni	soni	PROPN
admet-2338	289	11	,	,	PUNCT
admet-2338	289	12	a.	a.	NOUN
admet-2338	289	13	bhattarai	bhattarai	PROPN
admet-2338	289	14	.	.	PUNCT
admet-2338	290	1	recent	recent	ADJ
admet-2338	290	2	advances	advance	NOUN
admet-2338	290	3	in	in	ADP
admet-2338	290	4	improving	improve	VERB
admet-2338	290	5	the	the	DET
admet-2338	290	6	bioavailability	bioavailability	NOUN
admet-2338	290	7	of	of	ADP
admet-2338	290	8	hydrophobic	hydrophobic	NOUN
admet-2338	290	9	/	/	SYM
admet-2338	290	10	lipophilic	lipophilic	ADJ
admet-2338	290	11	drugs	drug	NOUN
admet-2338	290	12	and	and	CCONJ
admet-2338	290	13	their	their	PRON
admet-2338	290	14	delivery	delivery	NOUN
admet-2338	290	15	via	via	ADP
admet-2338	290	16	self	self	NOUN
admet-2338	290	17	-	-	PUNCT
admet-2338	290	18	emulsifying	emulsify	VERB
admet-2338	290	19	formulations	formulation	NOUN
admet-2338	290	20	.	.	PUNCT
admet-2338	291	1	colloids	colloid	NOUN
admet-2338	291	2	and	and	CCONJ
admet-2338	291	3	interfaces	interface	NOUN
admet-2338	291	4	7	7	NUM
admet-2338	291	5	(	(	PUNCT
admet-2338	291	6	2023	2023	NUM
admet-2338	291	7	)	)	PUNCT
admet-2338	291	8	16	16	NUM
admet-2338	291	9	.	.	PUNCT
admet-2338	292	1	https://doi.org/10.3390/colloids7010016	https://doi.org/10.3390/colloids7010016	PROPN
admet-2338	292	2	[	[	X
admet-2338	292	3	9	9	NUM
admet-2338	292	4	]	]	PUNCT
admet-2338	292	5	neusilin	neusilin	NOUN
admet-2338	292	6	®	®	NOUN
admet-2338	292	7	ulf2	ulf2	NOUN
admet-2338	292	8	.	.	PUNCT
admet-2338	293	1	https://www.pharmaexcipients.com/wp-content/uploads/2020/05/technical-datasheet_neusilin-ufl2_pharma.pdf	https://www.pharmaexcipients.com/wp-content/uploads/2020/05/technical-datasheet_neusilin-ufl2_pharma.pdf	NOUN
admet-2338	293	2	accessed	access	VERB
admet-2338	293	3	22/9/2022	22/9/2022	NUM
admet-2338	293	4	[	[	X
admet-2338	293	5	10	10	NUM
admet-2338	293	6	]	]	X
admet-2338	293	7	h.	h.	PROPN
admet-2338	293	8	wang	wang	PROPN
admet-2338	293	9	,	,	PUNCT
admet-2338	293	10	h.	h.	PROPN
admet-2338	293	11	wang	wang	PROPN
admet-2338	293	12	,	,	PUNCT
admet-2338	293	13	w.	w.	PROPN
admet-2338	293	14	yang	yang	PROPN
admet-2338	293	15	,	,	PUNCT
admet-2338	293	16	m.	m.	PROPN
admet-2338	293	17	yu	yu	PROPN
admet-2338	293	18	,	,	PUNCT
admet-2338	293	19	s.	s.	PROPN
admet-2338	293	20	sun	sun	PROPN
admet-2338	293	21	,	,	PUNCT
admet-2338	293	22	b.	b.	PROPN
admet-2338	293	23	xie	xie	PROPN
admet-2338	293	24	.	.	PUNCT
admet-2338	294	1	improved	improve	VERB
admet-2338	294	2	oral	oral	ADJ
admet-2338	294	3	bioavailability	bioavailability	NOUN
admet-2338	294	4	and	and	CCONJ
admet-2338	294	5	liver	liver	NOUN
admet-2338	294	6	targeting	targeting	NOUN
admet-2338	294	7	of	of	ADP
admet-2338	294	8	sorafenib	sorafenib	NOUN
admet-2338	294	9	solid	solid	ADJ
admet-2338	294	10	lipid	lipid	ADJ
admet-2338	294	11	nanoparticles	nanoparticle	NOUN
admet-2338	294	12	in	in	ADP
admet-2338	294	13	rats	rat	NOUN
admet-2338	294	14	.	.	PUNCT
admet-2338	295	1	aaps	aaps	PROPN
admet-2338	295	2	pharmaceutics	pharmaceutics	PROPN
admet-2338	295	3	&	&	CCONJ
admet-2338	295	4	drug	drug	PROPN
admet-2338	295	5	delivery	delivery	PROPN
admet-2338	295	6	research	research	NOUN
admet-2338	295	7	19	19	NUM
admet-2338	295	8	(	(	PUNCT
admet-2338	295	9	2018	2018	NUM
admet-2338	295	10	)	)	PUNCT
admet-2338	295	11	761	761	NUM
admet-2338	295	12	-	-	SYM
admet-2338	295	13	768	768	NUM
admet-2338	295	14	.	.	PUNCT
admet-2338	296	1	https://doi.org/10.1208/s12249-017-0901-3	https://doi.org/10.1208/s12249-017-0901-3	NUM
admet-2338	297	1	[	[	PUNCT
admet-2338	297	2	11	11	NUM
admet-2338	297	3	]	]	X
admet-2338	297	4	guo	guo	PROPN
admet-2338	297	5	y	y	PROPN
admet-2338	297	6	,	,	PUNCT
admet-2338	297	7	zhong	zhong	PROPN
admet-2338	297	8	t	t	PROPN
admet-2338	297	9	,	,	PUNCT
admet-2338	297	10	duan	duan	PROPN
admet-2338	297	11	xc	xc	PROPN
admet-2338	297	12	,	,	PUNCT
admet-2338	297	13	zhang	zhang	PROPN
admet-2338	297	14	s	s	PROPN
admet-2338	297	15	,	,	PUNCT
admet-2338	297	16	yao	yao	PROPN
admet-2338	297	17	x	x	PRON
admet-2338	297	18	,	,	PUNCT
admet-2338	297	19	yin	yin	PROPN
admet-2338	297	20	yf	yf	NOUN
admet-2338	297	21	.	.	PUNCT
admet-2338	297	22	improving	improve	VERB
admet-2338	297	23	anti	anti	ADJ
admet-2338	297	24	-	-	ADJ
admet-2338	297	25	tumor	tumor	ADJ
admet-2338	297	26	activity	activity	NOUN
admet-2338	297	27	of	of	ADP
admet-2338	297	28	sorafenib	sorafenib	NOUN
admet-2338	297	29	tosylate	tosylate	VERB
admet-2338	297	30	by	by	ADP
admet-2338	297	31	lipidand	lipidand	NOUN
admet-2338	297	32	polymer	polymer	NOUN
admet-2338	297	33	-	-	PUNCT
admet-2338	297	34	coated	coat	VERB
admet-2338	297	35	nanomatrix	nanomatrix	NOUN
admet-2338	297	36	.	.	PUNCT
admet-2338	298	1	drug	drug	NOUN
admet-2338	298	2	delivery	delivery	NOUN
admet-2338	298	3	24	24	NUM
admet-2338	298	4	(	(	PUNCT
admet-2338	298	5	2017	2017	NUM
admet-2338	298	6	)	)	PUNCT
admet-2338	298	7	270	270	NUM
admet-2338	298	8	-	-	SYM
admet-2338	298	9	277	277	NUM
admet-2338	298	10	.	.	PUNCT
admet-2338	298	11	https://doi.org/10.1080/10717544.2016.1245371	https://doi.org/10.1080/10717544.2016.1245371	PUNCT
admet-2338	299	1	[	[	X
admet-2338	299	2	12	12	NUM
admet-2338	299	3	]	]	PUNCT
admet-2338	299	4	x.	x.	PROPN
admet-2338	299	5	wang	wang	PROPN
admet-2338	299	6	,	,	PUNCT
admet-2338	299	7	j.	j.	PROPN
admet-2338	299	8	fan	fan	PROPN
admet-2338	299	9	,	,	PUNCT
admet-2338	299	10	y.	y.	PROPN
admet-2338	299	11	liu	liu	PROPN
admet-2338	299	12	,	,	PUNCT
admet-2338	299	13	b.	b.	PROPN
admet-2338	299	14	zhao	zhao	PROPN
admet-2338	299	15	,	,	PUNCT
admet-2338	299	16	z.	z.	PROPN
admet-2338	299	17	jia	jia	PROPN
admet-2338	299	18	,	,	PUNCT
admet-2338	299	19	q.	q.	PROPN
admet-2338	299	20	zhang	zhang	PROPN
admet-2338	299	21	.	.	PUNCT
admet-2338	299	22	bioavailability	bioavailability	NOUN
admet-2338	299	23	and	and	CCONJ
admet-2338	299	24	pharmacokinetics	pharmacokinetic	NOUN
admet-2338	299	25	of	of	ADP
admet-2338	299	26	sorafenib	sorafenib	NOUN
admet-2338	299	27	suspension	suspension	NOUN
admet-2338	299	28	,	,	PUNCT
admet-2338	299	29	nanoparticles	nanoparticle	NOUN
admet-2338	299	30	and	and	CCONJ
admet-2338	299	31	nanomatrix	nanomatrix	NOUN
admet-2338	299	32	for	for	ADP
admet-2338	299	33	oral	oral	ADJ
admet-2338	299	34	administration	administration	NOUN
admet-2338	299	35	to	to	PART
admet-2338	299	36	rat	rat	VERB
admet-2338	299	37	.	.	PROPN
admet-2338	299	38	international	international	ADJ
admet-2338	299	39	journal	journal	PROPN
admet-2338	299	40	of	of	ADP
admet-2338	299	41	pharmaceutics	pharmaceutic	NOUN
admet-2338	299	42	419	419	NUM
admet-2338	299	43	(	(	PUNCT
admet-2338	299	44	2011	2011	NUM
admet-2338	299	45	)	)	PUNCT
admet-2338	299	46	339	339	NUM
admet-2338	299	47	-	-	SYM
admet-2338	299	48	46	46	NUM
admet-2338	299	49	.	.	PUNCT
admet-2338	300	1	https://doi.org/10.1016/j.ijpharm.2011.08.003	https://doi.org/10.1016/j.ijpharm.2011.08.003	PROPN
admet-2338	300	2	[	[	X
admet-2338	300	3	13	13	NUM
admet-2338	300	4	]	]	X
admet-2338	300	5	m.l	m.l	PROPN
admet-2338	300	6	.	.	PROPN
admet-2338	300	7	bondi	bondi	PROPN
admet-2338	300	8	,	,	PUNCT
admet-2338	300	9	a.	a.	PROPN
admet-2338	300	10	scala	scala	PROPN
admet-2338	300	11	,	,	PUNCT
admet-2338	300	12	g.	g.	PROPN
admet-2338	300	13	sortino	sortino	PROPN
admet-2338	300	14	,	,	PUNCT
admet-2338	300	15	e.	e.	PROPN
admet-2338	300	16	amore	amore	PROPN
admet-2338	300	17	,	,	PUNCT
admet-2338	300	18	c.	c.	PROPN
admet-2338	300	19	botto	botto	PROPN
admet-2338	300	20	,	,	PUNCT
admet-2338	300	21	a.	a.	NOUN
admet-2338	300	22	azzolina	azzolina	NOUN
admet-2338	300	23	.	.	PUNCT
admet-2338	301	1	nano	nano	NOUN
admet-2338	301	2	assemblies	assembly	NOUN
admet-2338	301	3	based	base	VERB
admet-2338	301	4	on	on	ADP
admet-2338	301	5	supramolecular	supramolecular	ADJ
admet-2338	301	6	complexes	complex	NOUN
admet-2338	301	7	of	of	ADP
admet-2338	301	8	non	non	ADJ
admet-2338	301	9	-	-	ADJ
admet-2338	301	10	ionic	ionic	ADJ
admet-2338	301	11	amphiphilic	amphiphilic	ADJ
admet-2338	301	12	cyclodextrin	cyclodextrin	NOUN
admet-2338	301	13	and	and	CCONJ
admet-2338	301	14	sorafenib	sorafenib	NOUN
admet-2338	301	15	as	as	ADP
admet-2338	301	16	effective	effective	ADJ
admet-2338	301	17	weapons	weapon	NOUN
admet-2338	301	18	to	to	PART
admet-2338	301	19	kill	kill	VERB
admet-2338	301	20	human	human	ADJ
admet-2338	301	21	hcc	hcc	PROPN
admet-2338	301	22	cells	cell	NOUN
admet-2338	301	23	.	.	PUNCT
admet-2338	302	1	biomacromolecules	biomacromolecule	NOUN
admet-2338	302	2	16	16	NUM
admet-2338	302	3	(	(	PUNCT
admet-2338	302	4	2015	2015	NUM
admet-2338	302	5	)	)	PUNCT
admet-2338	302	6	3784	3784	NUM
admet-2338	302	7	-	-	SYM
admet-2338	302	8	3791	3791	NUM
admet-2338	302	9	.	.	PUNCT
admet-2338	303	1	https://doi.org/10.1021/acs.biomac.5b01082	https://doi.org/10.1021/acs.biomac.5b01082	X
admet-2338	304	1	[	[	X
admet-2338	304	2	14	14	NUM
admet-2338	304	3	]	]	X
admet-2338	304	4	r.	r.	PROPN
admet-2338	304	5	a.	a.	PROPN
admet-2338	304	6	aldeeb	aldeeb	PROPN
admet-2338	304	7	,	,	PUNCT
admet-2338	304	8	m.	m.	PROPN
admet-2338	304	9	f.	f.	PROPN
admet-2338	304	10	el	el	PROPN
admet-2338	304	11	-	-	PUNCT
admet-2338	304	12	miligi	miligi	PROPN
admet-2338	304	13	,	,	PUNCT
admet-2338	304	14	m.	m.	NOUN
admet-2338	304	15	el	el	PROPN
admet-2338	304	16	-	-	PUNCT
admet-2338	304	17	nabarawi	nabarawi	PROPN
admet-2338	304	18	,	,	PUNCT
admet-2338	304	19	r.	r.	PROPN
admet-2338	304	20	tag	tag	PROPN
admet-2338	304	21	,	,	PUNCT
admet-2338	304	22	h.	h.	PROPN
admet-2338	304	23	m.	m.	PROPN
admet-2338	304	24	s.	s.	PROPN
admet-2338	304	25	amin	amin	PROPN
admet-2338	304	26	and	and	CCONJ
admet-2338	304	27	a.	a.	NOUN
admet-2338	304	28	a.	a.	PROPN
admet-2338	304	29	taha	taha	PROPN
admet-2338	304	30	.	.	PUNCT
admet-2338	305	1	enhancement	enhancement	NOUN
admet-2338	305	2	of	of	ADP
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admet-2338	305	4	solubility	solubility	NOUN
admet-2338	305	5	and	and	CCONJ
admet-2338	305	6	dissolution	dissolution	NOUN
admet-2338	305	7	rate	rate	NOUN
admet-2338	305	8	of	of	ADP
admet-2338	305	9	telmisartan	telmisartan	NOUN
admet-2338	305	10	by	by	ADP
admet-2338	305	11	surface	surface	NOUN
admet-2338	305	12	solid	solid	ADJ
admet-2338	305	13	dispersions	dispersion	NOUN
admet-2338	305	14	employing	employ	VERB
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admet-2338	305	16	disintegrants	disintegrant	NOUN
admet-2338	305	17	,	,	PUNCT
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admet-2338	305	22	carriers	carrier	NOUN
admet-2338	305	23	.	.	PUNCT
admet-2338	306	1	scientia	scientia	PROPN
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admet-2338	306	4	(	(	PUNCT
admet-2338	306	5	2022	2022	NUM
admet-2338	306	6	)	)	PUNCT
admet-2338	306	7	71	71	NUM
admet-2338	306	8	.	.	PUNCT
admet-2338	307	1	https://doi.org/10.3390/scipharm90040071	https://doi.org/10.3390/scipharm90040071	PROPN
admet-2338	308	1	[	[	X
admet-2338	308	2	15	15	NUM
admet-2338	308	3	]	]	X
admet-2338	308	4	k.	k.	PROPN
admet-2338	308	5	jo	jo	PROPN
admet-2338	308	6	,	,	PUNCT
admet-2338	308	7	j.	j.	PROPN
admet-2338	308	8	m.	m.	PROPN
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admet-2338	308	10	,	,	PUNCT
admet-2338	308	11	h.	h.	PROPN
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admet-2338	308	13	,	,	PUNCT
admet-2338	308	14	e.	e.	PROPN
admet-2338	308	15	k.	k.	PROPN
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admet-2338	308	17	,	,	PUNCT
admet-2338	308	18	h.	h.	PROPN
admet-2338	308	19	c.	c.	PROPN
admet-2338	308	20	kim	kim	PROPN
admet-2338	308	21	,	,	PUNCT
admet-2338	308	22	h.	h.	PROPN
admet-2338	308	23	kim	kim	PROPN
admet-2338	308	24	,	,	PUNCT
admet-2338	308	25	j.	j.	PROPN
admet-2338	308	26	lee	lee	PROPN
admet-2338	308	27	.	.	PROPN
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admet-2338	308	38	-	-	PUNCT
admet-2338	308	39	based	base	VERB
admet-2338	308	40	dispersion	dispersion	NOUN
admet-2338	308	41	systems	system	NOUN
admet-2338	308	42	solidified	solidify	VERB
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admet-2338	308	44	adsorbent	adsorbent	NOUN
admet-2338	308	45	carriers	carrier	NOUN
admet-2338	308	46	.	.	PUNCT
admet-2338	309	1	pharmaceutics	pharmaceutic	NOUN
admet-2338	309	2	11	11	NUM
admet-2338	309	3	(	(	PUNCT
admet-2338	309	4	2015	2015	NUM
admet-2338	309	5	)	)	PUNCT
admet-2338	309	6	1	1	NUM
admet-2338	309	7	.	.	X
admet-2338	309	8	https://doi.org/10.3390/pharmaceutics11010001	https://doi.org/10.3390/pharmaceutics11010001	NOUN
admet-2338	309	9	https://pubmed.ncbi.nlm.nih.gov/29230141	https://pubmed.ncbi.nlm.nih.gov/29230141	PROPN
admet-2338	309	10	https://doi.org/10.1517/14656566.2010.496453	https://doi.org/10.1517/14656566.2010.496453	PUNCT
admet-2338	310	1	https://doi.org/10.3748/wjg.v24.i36.4152	https://doi.org/10.3748/wjg.v24.i36.4152	PROPN
admet-2338	310	2	https://doi.org/10.1016/j.powtec.2015.04.044	https://doi.org/10.1016/j.powtec.2015.04.044	PROPN
admet-2338	310	3	https://doi.org/10.1039/c5ra08550k	https://doi.org/10.1039/c5ra08550k	PROPN
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admet-2338	310	7	https://www.pharmaexcipients.com/wp-content/uploads/2020/05/technical-data-sheet_neusilin-ufl2_pharma.pdf	https://www.pharmaexcipients.com/wp-content/uploads/2020/05/technical-data-sheet_neusilin-ufl2_pharma.pdf	PROPN
admet-2338	310	8	https://www.pharmaexcipients.com/wp-content/uploads/2020/05/technical-data-sheet_neusilin-ufl2_pharma.pdf	https://www.pharmaexcipients.com/wp-content/uploads/2020/05/technical-data-sheet_neusilin-ufl2_pharma.pdf	PROPN
admet-2338	310	9	https://doi.org/10.1208/s12249-017-0901-3	https://doi.org/10.1208/s12249-017-0901-3	NUM
admet-2338	310	10	https://doi.org/10.1080/10717544.2016.1245371	https://doi.org/10.1080/10717544.2016.1245371	PROPN
admet-2338	311	1	https://doi.org/10.1016/j.ijpharm.2011.08.003	https://doi.org/10.1016/j.ijpharm.2011.08.003	PROPN
admet-2338	311	2	https://doi.org/10.1021/acs.biomac.5b01082	https://doi.org/10.1021/acs.biomac.5b01082	X
admet-2338	311	3	https://doi.org/10.3390/scipharm90040071	https://doi.org/10.3390/scipharm90040071	PROPN
admet-2338	311	4	https://doi.org/10.3390/pharmaceutics11010001	https://doi.org/10.3390/pharmaceutics11010001	NOUN
admet-2338	311	5	admet	admet	PROPN
admet-2338	311	6	&	&	CCONJ
admet-2338	311	7	dmpk	dmpk	PROPN
admet-2338	311	8	12(4	12(4	PROPN
admet-2338	311	9	)	)	PUNCT
admet-2338	311	10	(	(	PUNCT
admet-2338	311	11	2024	2024	NUM
admet-2338	311	12	)	)	PUNCT
admet-2338	311	13	687	687	NUM
admet-2338	311	14	-	-	SYM
admet-2338	311	15	702	702	NUM
admet-2338	311	16	neusilin	neusilin	PROPN
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admet-2338	311	21	dispersion	dispersion	NOUN
admet-2338	311	22	of	of	ADP
admet-2338	311	23	sorafenib	sorafenib	NOUN
admet-2338	311	24	tosylate	tosylate	VERB
admet-2338	311	25	doi	doi	NOUN
admet-2338	311	26	:	:	PUNCT
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admet-2338	311	28	701	701	NUM
admet-2338	311	29	[	[	SYM
admet-2338	311	30	16	16	NUM
admet-2338	311	31	]	]	X
admet-2338	311	32	a.r	a.r	PROPN
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admet-2338	311	34	tekade	tekade	PROPN
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admet-2338	311	37	.	.	PROPN
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admet-2338	311	39	.	.	PUNCT
admet-2338	312	1	a	a	DET
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admet-2338	312	7	carriers	carrier	NOUN
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admet-2338	312	9	therein	therein	ADV
admet-2338	312	10	for	for	ADP
admet-2338	312	11	solubility	solubility	NOUN
admet-2338	312	12	enhancement	enhancement	NOUN
admet-2338	312	13	of	of	ADP
admet-2338	312	14	poorly	poorly	ADV
admet-2338	312	15	water	water	NOUN
admet-2338	312	16	-	-	PUNCT
admet-2338	312	17	soluble	soluble	ADJ
admet-2338	312	18	drugs	drug	NOUN
admet-2338	312	19	.	.	PUNCT
admet-2338	313	1	advanced	advanced	ADJ
admet-2338	313	2	pharmaceutical	pharmaceutical	ADJ
admet-2338	313	3	bulletin	bulletin	NOUN
admet-2338	313	4	10	10	NUM
admet-2338	313	5	(	(	PUNCT
admet-2338	313	6	2020	2020	NUM
admet-2338	313	7	)	)	PUNCT
admet-2338	313	8	359	359	NUM
admet-2338	313	9	-	-	SYM
admet-2338	313	10	369	369	NUM
admet-2338	313	11	.	.	PUNCT
admet-2338	314	1	https://doi.org/10.34172/apb.2020.044	https://doi.org/10.34172/apb.2020.044	PROPN
admet-2338	315	1	[	[	X
admet-2338	315	2	17	17	NUM
admet-2338	315	3	]	]	PUNCT
admet-2338	315	4	t.	t.	NOUN
admet-2338	315	5	pandav	pandav	NOUN
admet-2338	315	6	,	,	PUNCT
admet-2338	315	7	p.	p.	NOUN
admet-2338	315	8	pant	pant	NOUN
admet-2338	315	9	,	,	PUNCT
admet-2338	315	10	t.	t.	NOUN
admet-2338	315	11	devare	devare	NOUN
admet-2338	315	12	and	and	CCONJ
admet-2338	315	13	a.	a.	NOUN
admet-2338	315	14	mali	mali	PROPN
admet-2338	315	15	.	.	PUNCT
admet-2338	316	1	development	development	NOUN
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admet-2338	316	3	posaconazole	posaconazole	NOUN
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admet-2338	316	6	formulation	formulation	NOUN
admet-2338	316	7	for	for	ADP
admet-2338	316	8	mucormycosis	mucormycosis	NOUN
admet-2338	316	9	by	by	ADP
admet-2338	316	10	hot	hot	ADJ
admet-2338	316	11	melt	melt	NOUN
admet-2338	316	12	extrusion	extrusion	NOUN
admet-2338	316	13	using	use	VERB
admet-2338	316	14	qbd	qbd	NOUN
admet-2338	316	15	approach	approach	NOUN
admet-2338	316	16	.	.	PUNCT
admet-2338	317	1	journal	journal	NOUN
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admet-2338	317	6	14(8	14(8	NUM
admet-2338	317	7	)	)	PUNCT
admet-2338	317	8	(	(	PUNCT
admet-2338	317	9	2023	2023	NUM
admet-2338	317	10	)	)	PUNCT
admet-2338	317	11	28	28	NUM
admet-2338	317	12	-	-	SYM
admet-2338	317	13	39	39	NUM
admet-2338	317	14	.	.	PUNCT
admet-2338	318	1	https://doi.org/10.55218/jasr.202314805	https://doi.org/10.55218/jasr.202314805	VERB
admet-2338	319	1	[	[	X
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admet-2338	319	11	gohel	gohel	PROPN
admet-2338	319	12	.	.	PUNCT
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admet-2338	320	4	dispersion	dispersion	NOUN
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admet-2338	320	8	.	.	PUNCT
admet-2338	321	1	journal	journal	NOUN
admet-2338	321	2	of	of	ADP
admet-2338	321	3	thermal	thermal	ADJ
admet-2338	321	4	analysis	analysis	NOUN
admet-2338	321	5	and	and	CCONJ
admet-2338	321	6	calorimetry	calorimetry	NOUN
admet-2338	321	7	120	120	NUM
admet-2338	321	8	(	(	PUNCT
admet-2338	321	9	2015	2015	NUM
admet-2338	321	10	)	)	PUNCT
admet-2338	321	11	699	699	NUM
admet-2338	321	12	-	-	SYM
admet-2338	321	13	709	709	NUM
admet-2338	321	14	.	.	PUNCT
admet-2338	322	1	https://doi.org/10.1007/s10973-014-3994-x	https://doi.org/10.1007/s10973-014-3994-x	PROPN
admet-2338	323	1	[	[	X
admet-2338	323	2	19	19	NUM
admet-2338	323	3	]	]	X
admet-2338	323	4	r.	r.	PROPN
admet-2338	323	5	censi	censi	PROPN
admet-2338	323	6	,	,	PUNCT
admet-2338	323	7	m.	m.	PROPN
admet-2338	323	8	r.	r.	PROPN
admet-2338	323	9	gigliobianco	gigliobianco	PROPN
admet-2338	323	10	,	,	PUNCT
admet-2338	323	11	a.	a.	NOUN
admet-2338	323	12	dubbini	dubbini	PROPN
admet-2338	323	13	,	,	PUNCT
admet-2338	323	14	l.	l.	PROPN
admet-2338	323	15	malaj	malaj	PROPN
admet-2338	323	16	and	and	CCONJ
admet-2338	323	17	p.	p.	NOUN
admet-2338	323	18	di	di	PROPN
admet-2338	323	19	martino	martino	PROPN
admet-2338	323	20	.	.	PUNCT
admet-2338	324	1	new	new	ADJ
admet-2338	324	2	nanometric	nanometric	ADJ
admet-2338	324	3	solid	solid	ADJ
admet-2338	324	4	dispersions	dispersion	NOUN
admet-2338	324	5	of	of	ADP
admet-2338	324	6	glibenclamide	glibenclamide	NOUN
admet-2338	324	7	in	in	ADP
admet-2338	324	8	neusilin	neusilin	PROPN
admet-2338	324	9	®	®	NOUN
admet-2338	324	10	ufl2	ufl2	NOUN
admet-2338	324	11	.	.	PUNCT
admet-2338	325	1	aaps	aap	NOUN
admet-2338	325	2	pharmscitech	pharmscitech	VERB
admet-2338	325	3	5	5	NUM
admet-2338	325	4	(	(	PUNCT
admet-2338	325	5	2016	2016	NUM
admet-2338	325	6	)	)	PUNCT
admet-2338	325	7	1204	1204	NUM
admet-2338	325	8	-	-	SYM
admet-2338	325	9	1212	1212	NUM
admet-2338	325	10	.	.	PUNCT
admet-2338	326	1	https://doi.org/10.1208/s12249-015-0457-z	https://doi.org/10.1208/s12249-015-0457-z	NOUN
admet-2338	326	2	[	[	X
admet-2338	326	3	20	20	NUM
admet-2338	326	4	]	]	PUNCT
admet-2338	326	5	x.	x.	PROPN
admet-2338	326	6	zhang	zhang	PROPN
admet-2338	326	7	,	,	PUNCT
admet-2338	326	8	h.	h.	PROPN
admet-2338	326	9	xing	xing	PROPN
admet-2338	326	10	,	,	PUNCT
admet-2338	326	11	y.	y.	PROPN
admet-2338	326	12	zhao	zhao	PROPN
admet-2338	326	13	,	,	PUNCT
admet-2338	326	14	z	z	PROPN
admet-2338	326	15	,	,	PUNCT
admet-2338	326	16	ma	ma	PROPN
admet-2338	326	17	.	.	PROPN
admet-2338	326	18	pharmaceutical	pharmaceutical	ADJ
admet-2338	326	19	dispersion	dispersion	NOUN
admet-2338	326	20	techniques	technique	NOUN
admet-2338	326	21	for	for	ADP
admet-2338	326	22	dissolution	dissolution	NOUN
admet-2338	326	23	and	and	CCONJ
admet-2338	326	24	bioavailability	bioavailability	NOUN
admet-2338	326	25	enhancement	enhancement	NOUN
admet-2338	326	26	of	of	ADP
admet-2338	326	27	poorly	poorly	ADV
admet-2338	326	28	water	water	NOUN
admet-2338	326	29	-	-	PUNCT
admet-2338	326	30	soluble	soluble	ADJ
admet-2338	326	31	drugs	drug	NOUN
admet-2338	326	32	.	.	PUNCT
admet-2338	327	1	pharmaceutics	pharmaceutic	NOUN
admet-2338	327	2	10	10	NUM
admet-2338	327	3	(	(	PUNCT
admet-2338	327	4	2018	2018	NUM
admet-2338	327	5	)	)	PUNCT
admet-2338	327	6	74	74	NUM
admet-2338	327	7	.	.	PUNCT
admet-2338	328	1	https://doi.org/10.3390/pharmaceutics10030074	https://doi.org/10.3390/pharmaceutics10030074	PROPN
admet-2338	328	2	[	[	X
admet-2338	328	3	21	21	NUM
admet-2338	328	4	]	]	X
admet-2338	328	5	j.	j.	PROPN
admet-2338	328	6	nandedkar	nandedkar	PROPN
admet-2338	328	7	,	,	PUNCT
admet-2338	328	8	m.	m.	PROPN
admet-2338	328	9	masane	masane	PROPN
admet-2338	328	10	,	,	PUNCT
admet-2338	328	11	a.j	a.j	PROPN
admet-2338	328	12	.	.	PROPN
admet-2338	328	13	mali	mali	PROPN
admet-2338	328	14	.	.	PUNCT
admet-2338	329	1	an	an	DET
admet-2338	329	2	optimisation	optimisation	NOUN
admet-2338	329	3	of	of	ADP
admet-2338	329	4	critical	critical	ADJ
admet-2338	329	5	quality	quality	NOUN
admet-2338	329	6	attributes	attribute	NOUN
admet-2338	329	7	for	for	ADP
admet-2338	329	8	acyclovir	acyclovir	PROPN
admet-2338	329	9	dispersible	dispersible	ADJ
admet-2338	329	10	tablets	tablet	NOUN
admet-2338	329	11	:	:	PUNCT
admet-2338	329	12	a	a	DET
admet-2338	329	13	quality	quality	NOUN
admet-2338	329	14	by	by	ADP
admet-2338	329	15	design	design	NOUN
admet-2338	329	16	approach	approach	NOUN
admet-2338	329	17	.	.	PUNCT
admet-2338	330	1	international	international	ADJ
admet-2338	330	2	journal	journal	NOUN
admet-2338	330	3	of	of	ADP
admet-2338	330	4	experimental	experimental	ADJ
admet-2338	330	5	design	design	NOUN
admet-2338	330	6	and	and	CCONJ
admet-2338	330	7	process	process	NOUN
admet-2338	330	8	optimisation	optimisation	NOUN
admet-2338	330	9	6	6	NUM
admet-2338	330	10	(	(	PUNCT
admet-2338	330	11	2020	2020	NUM
admet-2338	330	12	)	)	PUNCT
admet-2338	330	13	253	253	NUM
admet-2338	330	14	.	.	PUNCT
admet-2338	331	1	https://doi.org/10.1504/ijedpo.2020.113560	https://doi.org/10.1504/ijedpo.2020.113560	PROPN
admet-2338	331	2	[	[	X
admet-2338	331	3	22	22	NUM
admet-2338	331	4	]	]	PUNCT
admet-2338	331	5	c.	c.	PROPN
admet-2338	331	6	liu	liu	PROPN
admet-2338	331	7	,	,	PUNCT
admet-2338	331	8	z.	z.	PROPN
admet-2338	331	9	chen	chen	PROPN
admet-2338	331	10	,	,	PUNCT
admet-2338	331	11	y.	y.	PROPN
admet-2338	331	12	chen	chen	PROPN
admet-2338	331	13	,	,	PUNCT
admet-2338	331	14	j.	j.	PROPN
admet-2338	331	15	lu	lu	PROPN
admet-2338	331	16	,	,	PUNCT
admet-2338	331	17	y.	y.	PROPN
admet-2338	331	18	li	li	PROPN
admet-2338	331	19	,	,	PUNCT
admet-2338	331	20	s.	s.	PROPN
admet-2338	331	21	wang	wang	PROPN
admet-2338	331	22	.	.	PUNCT
admet-2338	332	1	improving	improve	VERB
admet-2338	332	2	oral	oral	ADJ
admet-2338	332	3	bioavailability	bioavailability	NOUN
admet-2338	332	4	of	of	ADP
admet-2338	332	5	sorafenib	sorafenib	NOUN
admet-2338	332	6	by	by	ADP
admet-2338	332	7	optimizing	optimize	VERB
admet-2338	332	8	the	the	DET
admet-2338	332	9	“	"	PUNCT
admet-2338	332	10	spring	spring	NOUN
admet-2338	332	11	”	"	PUNCT
admet-2338	332	12	and	and	CCONJ
admet-2338	332	13	“	"	PUNCT
admet-2338	332	14	parachute	parachute	NOUN
admet-2338	332	15	”	"	PUNCT
admet-2338	332	16	based	base	VERB
admet-2338	332	17	on	on	ADP
admet-2338	332	18	molecular	molecular	ADJ
admet-2338	332	19	interaction	interaction	NOUN
admet-2338	332	20	mechanisms	mechanism	NOUN
admet-2338	332	21	.	.	PUNCT
admet-2338	333	1	molecular	molecular	ADJ
admet-2338	333	2	pharmaceutics	pharmaceutic	NOUN
admet-2338	333	3	13	13	NUM
admet-2338	333	4	(	(	PUNCT
admet-2338	333	5	2016	2016	NUM
admet-2338	333	6	)	)	PUNCT
admet-2338	333	7	599	599	NUM
admet-2338	333	8	-	-	PUNCT
admet-2338	333	9	608	608	NUM
admet-2338	333	10	.	.	PUNCT
admet-2338	334	1	https://doi.org/10.1021/acs.molpharmaceut.5b00837	https://doi.org/10.1021/acs.molpharmaceut.5b00837	PRON
admet-2338	335	1	[	[	X
admet-2338	335	2	23	23	NUM
admet-2338	335	3	]	]	X
admet-2338	335	4	t.t	t.t	PROPN
admet-2338	335	5	.	.	PROPN
admet-2338	335	6	lin	lin	PROPN
admet-2338	335	7	,	,	PUNCT
admet-2338	335	8	d.y	d.y	PROPN
admet-2338	335	9	.	.	PROPN
admet-2338	335	10	gao	gao	PROPN
admet-2338	335	11	,	,	PUNCT
admet-2338	335	12	y.c	y.c	PROPN
admet-2338	335	13	.	.	PROPN
admet-2338	335	14	liu	liu	PROPN
admet-2338	335	15	,	,	PUNCT
admet-2338	335	16	y.c	y.c	PROPN
admet-2338	335	17	.	.	PROPN
admet-2338	335	18	sung	sung	PROPN
admet-2338	335	19	,	,	PUNCT
admet-2338	335	20	d.	d.	PROPN
admet-2338	335	21	wan	wan	PROPN
admet-2338	335	22	,	,	PUNCT
admet-2338	335	23	j.y	j.y	PROPN
admet-2338	335	24	.	.	PROPN
admet-2338	335	25	liu	liu	PROPN
admet-2338	335	26	.	.	PUNCT
admet-2338	335	27	development	development	NOUN
admet-2338	335	28	and	and	CCONJ
admet-2338	335	29	characterization	characterization	NOUN
admet-2338	335	30	of	of	ADP
admet-2338	335	31	sorafenibloaded	sorafenibloade	VERB
admet-2338	335	32	plga	plga	NOUN
admet-2338	335	33	nanoparticles	nanoparticle	NOUN
admet-2338	335	34	for	for	ADP
admet-2338	335	35	the	the	DET
admet-2338	335	36	systemic	systemic	ADJ
admet-2338	335	37	treatment	treatment	NOUN
admet-2338	335	38	of	of	ADP
admet-2338	335	39	liver	liver	NOUN
admet-2338	335	40	fibrosis	fibrosis	NOUN
admet-2338	335	41	.	.	PUNCT
admet-2338	336	1	journal	journal	PROPN
admet-2338	336	2	of	of	ADP
admet-2338	336	3	controlled	control	VERB
admet-2338	336	4	release	release	NOUN
admet-2338	336	5	221	221	NUM
admet-2338	336	6	(	(	PUNCT
admet-2338	336	7	2016	2016	NUM
admet-2338	336	8	)	)	PUNCT
admet-2338	336	9	62	62	NUM
admet-2338	336	10	-	-	SYM
admet-2338	336	11	70	70	NUM
admet-2338	336	12	.	.	PUNCT
admet-2338	337	1	https://doi.org/10.1016/j.jconrel.2015.11.003	https://doi.org/10.1016/j.jconrel.2015.11.003	PROPN
admet-2338	337	2	[	[	X
admet-2338	337	3	24	24	NUM
admet-2338	337	4	]	]	PUNCT
admet-2338	337	5	k.	k.	PROPN
admet-2338	337	6	kostelanská	kostelanská	PROPN
admet-2338	337	7	,	,	PUNCT
admet-2338	337	8	b.b	b.b	PROPN
admet-2338	337	9	.	.	PROPN
admet-2338	337	10	prudilová	prudilová	PROPN
admet-2338	337	11	,	,	PUNCT
admet-2338	337	12	s.	s.	PROPN
admet-2338	337	13	holešová	holešová	PROPN
admet-2338	337	14	s	s	PROPN
admet-2338	337	15	,	,	PUNCT
admet-2338	337	16	j.	j.	PROPN
admet-2338	337	17	vlček	vlček	PROPN
admet-2338	337	18	j	j	PROPN
admet-2338	337	19	,	,	PUNCT
admet-2338	337	20	d.	d.	PROPN
admet-2338	337	21	vetchý	vetchý	PROPN
admet-2338	337	22	,	,	PUNCT
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admet-2338	337	24	gajdziok	gajdziok	PROPN
admet-2338	337	25	.	.	PUNCT
admet-2338	338	1	comparative	comparative	ADJ
admet-2338	338	2	study	study	NOUN
admet-2338	338	3	of	of	ADP
admet-2338	338	4	powder	powder	NOUN
admet-2338	338	5	carriers	carrier	NOUN
admet-2338	338	6	physical	physical	ADJ
admet-2338	338	7	and	and	CCONJ
admet-2338	338	8	structural	structural	ADJ
admet-2338	338	9	properties	property	NOUN
admet-2338	338	10	.	.	PUNCT
admet-2338	339	1	pharmaceutics	pharmaceutic	NOUN
admet-2338	339	2	14	14	NUM
admet-2338	339	3	(	(	PUNCT
admet-2338	339	4	2022	2022	NUM
admet-2338	339	5	)	)	PUNCT
admet-2338	339	6	818	818	NUM
admet-2338	339	7	.	.	PUNCT
admet-2338	340	1	https://doi.org/10.3390/pharmaceutics14040818	https://doi.org/10.3390/pharmaceutics14040818	PROPN
admet-2338	340	2	[	[	X
admet-2338	340	3	25	25	NUM
admet-2338	340	4	]	]	PUNCT
admet-2338	340	5	a.	a.	NOUN
admet-2338	340	6	shah	shah	PROPN
admet-2338	340	7	,	,	PUNCT
admet-2338	340	8	a.t.m	a.t.m	PROPN
admet-2338	340	9	.	.	PUNCT
admet-2338	341	1	serajuddin	serajuddin	PROPN
admet-2338	341	2	.	.	PUNCT
admet-2338	342	1	conversion	conversion	NOUN
admet-2338	342	2	of	of	ADP
admet-2338	342	3	solid	solid	ADJ
admet-2338	342	4	dispersion	dispersion	NOUN
admet-2338	342	5	prepared	prepare	VERB
admet-2338	342	6	by	by	ADP
admet-2338	342	7	acid	acid	NOUN
admet-2338	342	8	-	-	PUNCT
admet-2338	342	9	base	base	NOUN
admet-2338	342	10	interaction	interaction	NOUN
admet-2338	342	11	into	into	ADP
admet-2338	342	12	free	free	ADV
admet-2338	342	13	-	-	PUNCT
admet-2338	342	14	flowing	flow	VERB
admet-2338	342	15	and	and	CCONJ
admet-2338	342	16	table	table	NOUN
admet-2338	342	17	powder	powder	NOUN
admet-2338	342	18	by	by	ADP
admet-2338	342	19	using	use	VERB
admet-2338	342	20	neusilin	neusilin	PROPN
admet-2338	342	21	®	®	PROPN
admet-2338	342	22	us2	us2	PROPN
admet-2338	342	23	.	.	PROPN
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admet-2338	342	25	journal	journal	PROPN
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admet-2338	342	28	484	484	NUM
admet-2338	342	29	(	(	PUNCT
admet-2338	342	30	2015	2015	NUM
admet-2338	342	31	)	)	PUNCT
admet-2338	342	32	172	172	NUM
admet-2338	342	33	-	-	SYM
admet-2338	342	34	180	180	NUM
admet-2338	342	35	.	.	PUNCT
admet-2338	343	1	https://doi:10.1016	https://doi:10.1016	PROPN
admet-2338	343	2	/	/	SYM
admet-2338	343	3	j.ijpharm.2015.02.060	j.ijpharm.2015.02.060	NOUN
admet-2338	343	4	[	[	X
admet-2338	343	5	26	26	NUM
admet-2338	343	6	]	]	X
admet-2338	343	7	c.a	c.a	PROPN
admet-2338	343	8	.	.	PROPN
admet-2338	343	9	bondi	bondi	PROPN
admet-2338	343	10	,	,	PUNCT
admet-2338	343	11	j.l	j.l	PROPN
admet-2338	343	12	.	.	PROPN
admet-2338	343	13	marks	marks	PROPN
admet-2338	343	14	,	,	PUNCT
admet-2338	343	15	l.b	l.b	PROPN
admet-2338	343	16	.	.	PROPN
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admet-2338	343	18	,	,	PUNCT
admet-2338	343	19	h.s	h.s	PROPN
admet-2338	343	20	.	.	PROPN
admet-2338	343	21	raatikainen	raatikainen	PROPN
admet-2338	343	22	,	,	PUNCT
admet-2338	343	23	s.r	s.r	PROPN
admet-2338	343	24	.	.	PROPN
admet-2338	343	25	lenox	lenox	PROPN
admet-2338	343	26	,	,	PUNCT
admet-2338	343	27	k.e	k.e	PROPN
admet-2338	343	28	.	.	PUNCT
admet-2338	343	29	gebhardt	gebhardt	PROPN
admet-2338	343	30	.	.	PUNCT
admet-2338	344	1	human	human	ADJ
admet-2338	344	2	and	and	CCONJ
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admet-2338	344	4	toxicity	toxicity	NOUN
admet-2338	344	5	of	of	ADP
admet-2338	344	6	sodium	sodium	NOUN
admet-2338	344	7	lauryl	lauryl	NOUN
admet-2338	344	8	sulfate	sulfate	NOUN
admet-2338	344	9	(	(	PUNCT
admet-2338	344	10	sls	sls	NOUN
admet-2338	344	11	):	):	PUNCT
admet-2338	344	12	evidence	evidence	NOUN
admet-2338	344	13	for	for	ADP
admet-2338	344	14	safe	safe	ADJ
admet-2338	344	15	use	use	NOUN
admet-2338	344	16	in	in	ADP
admet-2338	344	17	household	household	NOUN
admet-2338	344	18	cleaning	cleaning	NOUN
admet-2338	344	19	products	product	NOUN
admet-2338	344	20	.	.	PUNCT
admet-2338	345	1	environmental	environmental	ADJ
admet-2338	345	2	health	health	NOUN
admet-2338	345	3	insights	insight	NOUN
admet-2338	345	4	9	9	NUM
admet-2338	345	5	(	(	PUNCT
admet-2338	345	6	2015	2015	NUM
admet-2338	345	7	)	)	PUNCT
admet-2338	345	8	27	27	NUM
admet-2338	345	9	-	-	SYM
admet-2338	345	10	32	32	NUM
admet-2338	345	11	.	.	PUNCT
admet-2338	346	1	https://doi:10.4137	https://doi:10.4137	X
admet-2338	346	2	/	/	SYM
admet-2338	346	3	ehi.s31765	ehi.s31765	PUNCT
admet-2338	347	1	[	[	X
admet-2338	347	2	27	27	NUM
admet-2338	347	3	]	]	X
admet-2338	347	4	n.	n.	PROPN
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admet-2338	347	6	,	,	PUNCT
admet-2338	347	7	m.	m.	NOUN
admet-2338	347	8	shafiee	shafiee	PROPN
admet-2338	347	9	panah	panah	PROPN
admet-2338	347	10	.	.	PUNCT
admet-2338	348	1	the	the	DET
admet-2338	348	2	effect	effect	NOUN
admet-2338	348	3	of	of	ADP
admet-2338	348	4	surfactant	surfactant	ADJ
admet-2338	348	5	type	type	NOUN
admet-2338	348	6	and	and	CCONJ
admet-2338	348	7	concentration	concentration	NOUN
admet-2338	348	8	on	on	ADP
admet-2338	348	9	physicochemical	physicochemical	ADJ
admet-2338	348	10	properties	property	NOUN
admet-2338	348	11	of	of	ADP
admet-2338	348	12	carvedilol	carvedilol	PROPN
admet-2338	348	13	solid	solid	ADJ
admet-2338	348	14	dispersions	dispersion	NOUN
admet-2338	348	15	prepared	prepare	VERB
admet-2338	348	16	by	by	ADP
admet-2338	348	17	wet	wet	ADJ
admet-2338	348	18	milling	milling	NOUN
admet-2338	348	19	method	method	NOUN
admet-2338	348	20	.	.	PUNCT
admet-2338	349	1	iranian	iranian	ADJ
admet-2338	349	2	journal	journal	PROPN
admet-2338	349	3	of	of	ADP
admet-2338	349	4	pharmaceutical	pharmaceutical	PROPN
admet-2338	349	5	research	research	NOUN
admet-2338	349	6	21	21	NUM
admet-2338	349	7	(	(	PUNCT
admet-2338	349	8	2022	2022	NUM
admet-2338	349	9	)	)	PUNCT
admet-2338	349	10	e126913	e126913	NOUN
admet-2338	349	11	.	.	PUNCT
admet-2338	350	1	https://doi:10.5812	https://doi:10.5812	PROPN
admet-2338	350	2	/	/	SYM
admet-2338	350	3	ijpr-126913	ijpr-126913	PROPN
admet-2338	350	4	[	[	X
admet-2338	350	5	28	28	NUM
admet-2338	350	6	]	]	X
admet-2338	350	7	a.	a.	NOUN
admet-2338	350	8	mali	mali	PROPN
admet-2338	350	9	,	,	PUNCT
admet-2338	350	10	s.	s.	PROPN
admet-2338	350	11	rajalakshmi	rajalakshmi	PROPN
admet-2338	350	12	,	,	PUNCT
admet-2338	350	13	a.p	a.p	PROPN
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admet-2338	350	15	and	and	CCONJ
admet-2338	350	16	c.	c.	PROPN
admet-2338	350	17	bothiraja	bothiraja	PROPN
admet-2338	350	18	.	.	PUNCT
admet-2338	351	1	crystal	crystal	NOUN
admet-2338	351	2	engineering	engineering	PROPN
admet-2338	351	3	of	of	ADP
admet-2338	351	4	bioactive	bioactive	PROPN
admet-2338	351	5	plumbagin	plumbagin	NOUN
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admet-2338	351	7	antisolvent	antisolvent	NOUN
admet-2338	351	8	precipitation	precipitation	NOUN
admet-2338	351	9	,	,	PUNCT
admet-2338	351	10	melt	melt	VERB
admet-2338	351	11	solidification	solidification	NOUN
admet-2338	351	12	and	and	CCONJ
admet-2338	351	13	sonocrystallization	sonocrystallization	NOUN
admet-2338	351	14	techniques	technique	NOUN
admet-2338	351	15	.	.	PUNCT
admet-2338	352	1	materials	material	NOUN
admet-2338	352	2	research	research	NOUN
admet-2338	352	3	express	express	VERB
admet-2338	352	4	1(2	1(2	NUM
admet-2338	352	5	)	)	PUNCT
admet-2338	352	6	2014	2014	NUM
admet-2338	352	7	,	,	PUNCT
admet-2338	352	8	025405	025405	NUM
admet-2338	352	9	.	.	PUNCT
admet-2338	353	1	https://doi.org/10.1088/2053-1591/1/2/025405	https://doi.org/10.1088/2053-1591/1/2/025405	X
admet-2338	353	2	[	[	X
admet-2338	353	3	29	29	NUM
admet-2338	353	4	]	]	PUNCT
admet-2338	353	5	a.	a.	NOUN
admet-2338	353	6	akram	akram	PROPN
admet-2338	353	7	,	,	PUNCT
admet-2338	353	8	m.	m.	NOUN
admet-2338	353	9	irfan	irfan	PROPN
admet-2338	353	10	,	,	PUNCT
admet-2338	353	11	w.a	w.a	PROPN
admet-2338	353	12	.	.	PROPN
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admet-2338	353	14	,	,	PUNCT
admet-2338	353	15	d.m	d.m	PROPN
admet-2338	353	16	.	.	PUNCT
admet-2338	354	1	bukhary	bukhary	ADJ
admet-2338	354	2	,	,	PUNCT
admet-2338	354	3	m.	m.	NOUN
admet-2338	354	4	alissa	alissa	PROPN
admet-2338	354	5	.	.	PUNCT
admet-2338	355	1	how	how	SCONJ
admet-2338	355	2	to	to	PART
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admet-2338	355	4	solubility	solubility	NOUN
admet-2338	355	5	and	and	CCONJ
admet-2338	355	6	dissolution	dissolution	NOUN
admet-2338	355	7	of	of	ADP
admet-2338	355	8	irbesartan	irbesartan	PROPN
admet-2338	355	9	by	by	ADP
admet-2338	355	10	fabricating	fabricate	VERB
admet-2338	355	11	ternary	ternary	ADJ
admet-2338	355	12	solid	solid	ADJ
admet-2338	355	13	dispersions	dispersion	NOUN
admet-2338	355	14	:	:	PUNCT
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admet-2338	355	16	and	and	CCONJ
admet-2338	355	17	in	in	ADP
admet-2338	355	18	-	-	PUNCT
admet-2338	355	19	vitro	vitro	X
admet-2338	355	20	characterization	characterization	NOUN
admet-2338	355	21	.	.	PUNCT
admet-2338	356	1	pharmaceutics	pharmaceutic	NOUN
admet-2338	356	2	14	14	NUM
admet-2338	356	3	(	(	PUNCT
admet-2338	356	4	2022	2022	NUM
admet-2338	356	5	)	)	PUNCT
admet-2338	356	6	2264	2264	NUM
admet-2338	356	7	.	.	PUNCT
admet-2338	357	1	https://doi.org/10.3390/pharmaceutics14112264	https://doi.org/10.3390/pharmaceutics14112264	NOUN
admet-2338	357	2	[	[	X
admet-2338	357	3	30	30	NUM
admet-2338	357	4	]	]	X
admet-2338	357	5	l.a	l.a	PROPN
admet-2338	357	6	.	.	PROPN
admet-2338	357	7	j	j	PROPN
admet-2338	357	8	hamidu	hamidu	PROPN
admet-2338	357	9	,	,	PUNCT
admet-2338	357	10	u.o	u.o	PROPN
admet-2338	357	11	.	.	PROPN
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admet-2338	357	13	,	,	PUNCT
admet-2338	357	14	o.a	o.a	PROPN
admet-2338	357	15	.	.	PROPN
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admet-2338	357	17	,	,	PUNCT
admet-2338	357	18	i.m	i.m	PROPN
admet-2338	357	19	.	.	PUNCT
admet-2338	358	1	muhammad	muhammad	PROPN
admet-2338	358	2	.	.	PUNCT
admet-2338	359	1	d	d	X
admet-2338	359	2	-	-	ADJ
admet-2338	359	3	optimal	optimal	ADJ
admet-2338	359	4	response	response	NOUN
admet-2338	359	5	mixture	mixture	NOUN
admet-2338	359	6	design	design	NOUN
admet-2338	359	7	modeling	modeling	NOUN
admet-2338	359	8	of	of	ADP
admet-2338	359	9	polystyrene	polystyrene	NOUN
admet-2338	359	10	waste	waste	NOUN
admet-2338	359	11	adhesive	adhesive	ADJ
admet-2338	359	12	formulations	formulation	NOUN
admet-2338	359	13	.	.	PUNCT
admet-2338	360	1	international	international	ADJ
admet-2338	360	2	journal	journal	NOUN
admet-2338	360	3	of	of	ADP
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admet-2338	360	6	and	and	CCONJ
admet-2338	360	7	management	management	NOUN
admet-2338	360	8	research	research	NOUN
admet-2338	360	9	8	8	NUM
admet-2338	360	10	(	(	PUNCT
admet-2338	360	11	2021	2021	NUM
admet-2338	360	12	)	)	PUNCT
admet-2338	360	13	7	7	NUM
admet-2338	360	14	-	-	SYM
admet-2338	360	15	17	17	NUM
admet-2338	360	16	.	.	PUNCT
admet-2338	361	1	https://doi.org/10.29121/ijetmr.v8.i3.2021.867	https://doi.org/10.29121/ijetmr.v8.i3.2021.867	PRON
admet-2338	362	1	[	[	X
admet-2338	362	2	31	31	NUM
admet-2338	362	3	]	]	X
admet-2338	362	4	y.	y.	PROPN
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admet-2338	362	6	reddy	reddy	PROPN
admet-2338	362	7	,	,	PUNCT
admet-2338	362	8	d.	d.	PROPN
admet-2338	362	9	kalpana	kalpana	PROPN
admet-2338	362	10	.	.	PUNCT
admet-2338	363	1	formulation	formulation	NOUN
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admet-2338	363	3	and	and	CCONJ
admet-2338	363	4	evaluation	evaluation	NOUN
admet-2338	363	5	of	of	ADP
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admet-2338	363	8	tablet	tablet	NOUN
admet-2338	363	9	dosage	dosage	NOUN
admet-2338	363	10	form	form	NOUN
admet-2338	363	11	of	of	ADP
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admet-2338	363	13	tosylate	tosylate	VERB
admet-2338	363	14	.	.	PUNCT
admet-2338	364	1	asian	asian	ADJ
admet-2338	364	2	journal	journal	PROPN
admet-2338	364	3	of	of	ADP
admet-2338	364	4	pharmacy	pharmacy	NOUN
admet-2338	364	5	and	and	CCONJ
admet-2338	364	6	technology	technology	NOUN
admet-2338	364	7	10	10	NUM
admet-2338	364	8	(	(	PUNCT
admet-2338	364	9	2020	2020	NUM
admet-2338	364	10	)	)	PUNCT
admet-2338	364	11	38	38	NUM
admet-2338	364	12	-	-	SYM
admet-2338	364	13	42	42	NUM
admet-2338	364	14	.	.	PUNCT
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admet-2338	365	2	[	[	PUNCT
admet-2338	365	3	32	32	NUM
admet-2338	365	4	]	]	PUNCT
admet-2338	365	5	a.	a.	NOUN
admet-2338	365	6	yeardley	yeardley	PROPN
admet-2338	365	7	,	,	PUNCT
admet-2338	365	8	g.	g.	PROPN
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admet-2338	365	10	,	,	PUNCT
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admet-2338	365	13	.	.	PUNCT
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admet-2338	366	5	to	to	ADP
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admet-2338	366	7	-	-	ADJ
admet-2338	366	8	zro2	zro2	ADJ
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admet-2338	366	11	on	on	ADP
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admet-2338	366	14	ex	ex	PROPN
admet-2338	366	15	-	-	ADJ
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admet-2338	366	18	.	.	PUNCT
admet-2338	367	1	molecules	molecule	NOUN
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admet-2338	367	3	(	(	PUNCT
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admet-2338	367	5	)	)	PUNCT
admet-2338	367	6	827	827	NUM
admet-2338	367	7	.	.	PUNCT
admet-2338	368	1	https://doi.org/10.3390/molecules26040827	https://doi.org/10.3390/molecules26040827	PROPN
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admet-2338	368	13	/	/	SYM
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admet-2338	368	20	ijpr-126913	ijpr-126913	PROPN
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admet-2338	369	1	https://doi.org/10.3390/pharmaceutics14112264	https://doi.org/10.3390/pharmaceutics14112264	NOUN
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admet-2338	369	4	https://doi.org/10.3390/molecules26040827	https://doi.org/10.3390/molecules26040827	PROPN
admet-2338	369	5	b.	b.	PROPN
admet-2338	369	6	kumar	kumar	PROPN
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admet-2338	369	9	al	al	PROPN
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admet-2338	369	14	12(4	12(4	PROPN
admet-2338	369	15	)	)	PUNCT
admet-2338	369	16	(	(	PUNCT
admet-2338	369	17	2024	2024	NUM
admet-2338	369	18	)	)	PUNCT
admet-2338	369	19	687	687	NUM
admet-2338	369	20	-	-	SYM
admet-2338	369	21	702	702	NUM
admet-2338	369	22	702	702	NUM
admet-2338	370	1	[	[	SYM
admet-2338	370	2	33	33	NUM
admet-2338	370	3	]	]	X
admet-2338	370	4	r.b	r.b	PROPN
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admet-2338	370	7	,	,	PUNCT
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admet-2338	370	9	.	.	PROPN
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admet-2338	370	11	,	,	PUNCT
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admet-2338	370	15	.	.	PUNCT
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admet-2338	371	12	.	.	PUNCT
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admet-2338	372	6	and	and	CCONJ
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admet-2338	372	9	(	(	PUNCT
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admet-2338	372	11	)	)	PUNCT
admet-2338	372	12	4236	4236	NUM
admet-2338	372	13	-	-	SYM
admet-2338	372	14	4242	4242	NUM
admet-2338	372	15	.	.	PUNCT
admet-2338	373	1	https://doi.org/10.13040/ijpsr.0975-8232.6(10).4236-42	https://doi.org/10.13040/ijpsr.0975-8232.6(10).4236-42	NOUN
admet-2338	373	2	[	[	X
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admet-2338	373	4	]	]	X
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admet-2338	373	10	.	.	PROPN
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admet-2338	373	12	.	.	PUNCT
admet-2338	374	1	a	a	DET
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admet-2338	374	3	on	on	ADP
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admet-2338	374	6	and	and	CCONJ
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admet-2338	374	9	therein	therein	ADV
admet-2338	374	10	for	for	ADP
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admet-2338	374	12	enhancement	enhancement	NOUN
admet-2338	374	13	of	of	ADP
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admet-2338	374	16	-	-	PUNCT
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admet-2338	374	18	drugs	drug	NOUN
admet-2338	374	19	.	.	PUNCT
admet-2338	375	1	advanced	advanced	ADJ
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admet-2338	375	5	(	(	PUNCT
admet-2338	375	6	2020	2020	NUM
admet-2338	375	7	)	)	PUNCT
admet-2338	375	8	359	359	NUM
admet-2338	375	9	-	-	SYM
admet-2338	375	10	369	369	NUM
admet-2338	375	11	.	.	PUNCT
admet-2338	376	1	https://doi.org/10.34172/apb.2020.044	https://doi.org/10.34172/apb.2020.044	PROPN
admet-2338	377	1	[	[	X
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admet-2338	377	3	]	]	X
admet-2338	377	4	g.	g.	PROPN
admet-2338	377	5	wiergowska	wiergowska	PROPN
admet-2338	377	6	,	,	PUNCT
admet-2338	377	7	a.	a.	NOUN
admet-2338	377	8	stasiłowicz	stasiłowicz	PROPN
admet-2338	377	9	,	,	PUNCT
admet-2338	377	10	a.	a.	NOUN
admet-2338	377	11	miklaszewski	miklaszewski	PROPN
admet-2338	377	12	,	,	PUNCT
admet-2338	377	13	k.	k.	PROPN
admet-2338	377	14	lewandowska	lewandowska	PROPN
admet-2338	377	15	,	,	PUNCT
admet-2338	377	16	j.	j.	PROPN
admet-2338	377	17	cielecka	cielecka	PROPN
admet-2338	377	18	-	-	PUNCT
admet-2338	377	19	piontek	piontek	PROPN
admet-2338	377	20	.	.	PUNCT
admet-2338	378	1	structural	structural	ADJ
admet-2338	378	2	polymorphism	polymorphism	NOUN
admet-2338	378	3	of	of	ADP
admet-2338	378	4	sorafenib	sorafenib	NOUN
admet-2338	378	5	tosylate	tosylate	VERB
admet-2338	378	6	as	as	ADP
admet-2338	378	7	a	a	DET
admet-2338	378	8	key	key	ADJ
admet-2338	378	9	factor	factor	NOUN
admet-2338	378	10	in	in	ADP
admet-2338	378	11	its	its	PRON
admet-2338	378	12	solubility	solubility	NOUN
admet-2338	378	13	differentiation	differentiation	NOUN
admet-2338	378	14	.	.	PUNCT
admet-2338	379	1	pharmaceutics	pharmaceutic	NOUN
admet-2338	379	2	13	13	NUM
admet-2338	379	3	(	(	PUNCT
admet-2338	379	4	2021	2021	NUM
admet-2338	379	5	)	)	PUNCT
admet-2338	379	6	384	384	NUM
admet-2338	379	7	.	.	PUNCT
admet-2338	379	8	https://doi.org/10.3390/pharmaceutics13030384	https://doi.org/10.3390/pharmaceutics13030384	PROPN
admet-2338	380	1	[	[	X
admet-2338	380	2	36	36	NUM
admet-2338	380	3	]	]	PUNCT
admet-2338	380	4	m.	m.	NOUN
admet-2338	380	5	rao	rao	PROPN
admet-2338	380	6	,	,	PUNCT
admet-2338	380	7	y.	y.	PROPN
admet-2338	380	8	mandage	mandage	PROPN
admet-2338	380	9	,	,	PUNCT
admet-2338	380	10	k.	k.	PROPN
admet-2338	380	11	thanki	thanki	PROPN
admet-2338	380	12	,	,	PUNCT
admet-2338	380	13	s.	s.	PROPN
admet-2338	380	14	bhise	bhise	PROPN
admet-2338	380	15	.	.	PUNCT
admet-2338	381	1	dissolution	dissolution	ADJ
admet-2338	381	2	improvement	improvement	NOUN
admet-2338	381	3	of	of	ADP
admet-2338	381	4	simvastatin	simvastatin	NOUN
admet-2338	381	5	by	by	ADP
admet-2338	381	6	surface	surface	NOUN
admet-2338	381	7	solid	solid	ADJ
admet-2338	381	8	dispersion	dispersion	NOUN
admet-2338	381	9	technology	technology	NOUN
admet-2338	381	10	.	.	PUNCT
admet-2338	382	1	dissolution	dissolution	PROPN
admet-2338	382	2	technology	technology	NOUN
admet-2338	382	3	17	17	NUM
admet-2338	382	4	(	(	PUNCT
admet-2338	382	5	2020	2020	NUM
admet-2338	382	6	)	)	PUNCT
admet-2338	382	7	27	27	NUM
admet-2338	382	8	-	-	SYM
admet-2338	382	9	34	34	NUM
admet-2338	382	10	.	.	PUNCT
admet-2338	383	1	https://doi.org/10.14227/dt170210p27	https://doi.org/10.14227/dt170210p27	PROPN
admet-2338	383	2	[	[	X
admet-2338	383	3	37	37	NUM
admet-2338	383	4	]	]	PUNCT
admet-2338	383	5	t.	t.	PROPN
admet-2338	383	6	kiran	kiran	PROPN
admet-2338	383	7	,	,	PUNCT
admet-2338	383	8	nalini	nalini	PROPN
admet-2338	383	9	shastri	shastri	PROPN
admet-2338	383	10	,	,	PUNCT
admet-2338	383	11	sistla	sistla	PROPN
admet-2338	383	12	ramakrishna	ramakrishna	PROPN
admet-2338	383	13	,	,	PUNCT
admet-2338	383	14	m.	m.	NOUN
admet-2338	383	15	sadanandam	sadanandam	NOUN
admet-2338	383	16	.	.	PUNCT
admet-2338	384	1	surface	surface	PROPN
admet-2338	384	2	solid	solid	ADJ
admet-2338	384	3	dispersion	dispersion	NOUN
admet-2338	384	4	of	of	ADP
admet-2338	384	5	glimepiride	glimepiride	NOUN
admet-2338	384	6	for	for	ADP
admet-2338	384	7	enhancement	enhancement	NOUN
admet-2338	384	8	of	of	ADP
admet-2338	384	9	dissolution	dissolution	ADJ
admet-2338	384	10	rate	rate	NOUN
admet-2338	384	11	.	.	PUNCT
admet-2338	385	1	international	international	ADJ
admet-2338	385	2	journal	journal	PROPN
admet-2338	385	3	of	of	ADP
admet-2338	385	4	pharmaceutical	pharmaceutical	NOUN
admet-2338	385	5	technology	technology	NOUN
admet-2338	385	6	research	research	NOUN
admet-2338	385	7	1	1	NUM
admet-2338	385	8	(	(	PUNCT
admet-2338	385	9	2009	2009	NUM
admet-2338	385	10	)	)	PUNCT
admet-2338	385	11	822	822	NUM
admet-2338	385	12	-	-	SYM
admet-2338	385	13	831	831	NUM
admet-2338	385	14	.	.	PUNCT
admet-2338	386	1	https://sphinxsai.com/ptvol3/pt=66,nalini%20s,(822-831).pdf	https://sphinxsai.com/ptvol3/pt=66,nalini%20s,(822-831).pdf	NOUN
admet-2338	386	2	[	[	X
admet-2338	386	3	38	38	NUM
admet-2338	386	4	]	]	X
admet-2338	386	5	a.j	a.j	PROPN
admet-2338	386	6	.	.	PROPN
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admet-2338	386	8	,	,	PUNCT
admet-2338	386	9	a.	a.	NOUN
admet-2338	386	10	rokade	rokade	NOUN
admet-2338	386	11	,	,	PUNCT
admet-2338	386	12	r.	r.	PROPN
admet-2338	386	13	kamble	kamble	PROPN
admet-2338	386	14	.	.	PUNCT
admet-2338	387	1	resveratrol	resveratrol	NOUN
admet-2338	387	2	-	-	PUNCT
admet-2338	387	3	loaded	load	VERB
admet-2338	387	4	microsponge	microsponge	NOUN
admet-2338	387	5	as	as	ADP
admet-2338	387	6	a	a	DET
admet-2338	387	7	novel	novel	ADJ
admet-2338	387	8	biodegradable	biodegradable	ADJ
admet-2338	387	9	carrier	carrier	NOUN
admet-2338	387	10	for	for	ADP
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admet-2338	387	12	powder	powder	NOUN
admet-2338	387	13	inhaler	inhaler	NOUN
admet-2338	387	14	:	:	PUNCT
admet-2338	387	15	a	a	DET
admet-2338	387	16	new	new	ADJ
admet-2338	387	17	strategy	strategy	NOUN
admet-2338	387	18	in	in	ADP
admet-2338	387	19	lung	lung	NOUN
admet-2338	387	20	delivery	delivery	NOUN
admet-2338	387	21	.	.	PUNCT
admet-2338	388	1	bionanosci	bionanosci	NOUN
admet-2338	388	2	11	11	NUM
admet-2338	388	3	(	(	PUNCT
admet-2338	388	4	2021	2021	NUM
admet-2338	388	5	)	)	PUNCT
admet-2338	388	6	32	32	NUM
admet-2338	388	7	-	-	SYM
admet-2338	388	8	43	43	NUM
admet-2338	388	9	.	.	PUNCT
admet-2338	389	1	https://doi.org/10.1007/s12668-020-00800-7	https://doi.org/10.1007/s12668-020-00800-7	NUM
admet-2338	389	2	e	e	X
admet-2338	389	3	a	a	DET
admet-2338	389	4	essa	essa	PROPN
admet-2338	389	5	.	.	PUNCT
admet-2338	389	6	enhancement	enhancement	NOUN
admet-2338	389	7	of	of	ADP
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admet-2338	389	9	dissolution	dissolution	PROPN
admet-2338	389	10	;	;	PUNCT
admet-2338	389	11	surface	surface	VERB
admet-2338	389	12	solid	solid	ADJ
admet-2338	389	13	dispersion	dispersion	NOUN
admet-2338	389	14	versus	versus	ADP
admet-2338	389	15	solid	solid	ADJ
admet-2338	389	16	dispersion	dispersion	NOUN
admet-2338	389	17	.	.	PUNCT
admet-2338	390	1	asian	asian	ADJ
admet-2338	390	2	journal	journal	PROPN
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admet-2338	390	5	9	9	NUM
admet-2338	390	6	(	(	PUNCT
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admet-2338	390	8	)	)	PUNCT
admet-2338	390	9	283	283	NUM
admet-2338	390	10	-	-	SYM
admet-2338	390	11	289	289	NUM
admet-2338	390	12	.	.	PUNCT
admet-2338	391	1	https://www.asiapharmaceutics.info/index.php/ajp/article/download/469/403/1305	https://www.asiapharmaceutics.info/index.php/ajp/article/download/469/403/1305	NOUN
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admet-2338	392	2	39	39	NUM
admet-2338	392	3	]	]	PUNCT
admet-2338	392	4	i.	i.	NOUN
admet-2338	392	5	choi	choi	PROPN
admet-2338	392	6	,	,	PUNCT
admet-2338	392	7	s.y	s.y	PROPN
admet-2338	392	8	.	.	PROPN
admet-2338	392	9	park	park	PROPN
admet-2338	392	10	,	,	PUNCT
admet-2338	392	11	s.w	s.w	PROPN
admet-2338	392	12	.	.	PROPN
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admet-2338	392	14	,	,	PUNCT
admet-2338	392	15	z.	z.	PROPN
admet-2338	392	16	kang	kang	PROPN
admet-2338	392	17	,	,	PUNCT
admet-2338	392	18	y.	y.	PROPN
admet-2338	392	19	s.	s.	PROPN
admet-2338	392	20	jin	jin	PROPN
admet-2338	392	21	,	,	PUNCT
admet-2338	392	22	i.	i.	PROPN
admet-2338	392	23	w.	w.	PROPN
admet-2338	392	24	kim	kim	PROPN
admet-2338	392	25	.	.	PUNCT
admet-2338	393	1	dissolution	dissolution	PROPN
admet-2338	393	2	enhancement	enhancement	NOUN
admet-2338	393	3	of	of	ADP
admet-2338	393	4	sorafenib	sorafenib	NOUN
admet-2338	393	5	tosylate	tosylate	VERB
admet-2338	393	6	by	by	ADP
admet-2338	393	7	co	co	VERB
admet-2338	393	8	-	-	NOUN
admet-2338	393	9	milling	mill	VERB
admet-2338	393	10	with	with	ADP
admet-2338	393	11	tetradecanol	tetradecanol	ADJ
admet-2338	393	12	post	post	ADJ
admet-2338	393	13	-	-	ADJ
admet-2338	393	14	extracted	extract	VERB
admet-2338	393	15	using	use	VERB
admet-2338	393	16	supercritical	supercritical	ADJ
admet-2338	393	17	carbon	carbon	NOUN
admet-2338	393	18	dioxide	dioxide	NOUN
admet-2338	393	19	.	.	PUNCT
admet-2338	394	1	pharmazie	pharmazie	NOUN
admet-2338	394	2	75	75	NUM
admet-2338	394	3	(	(	PUNCT
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admet-2338	394	5	)	)	PUNCT
admet-2338	394	6	13	13	NUM
admet-2338	394	7	-	-	SYM
admet-2338	394	8	7	7	NUM
admet-2338	394	9	.	.	PUNCT
admet-2338	395	1	https://doi.org/10.1691/ph.2020.9120	https://doi.org/10.1691/ph.2020.9120	ADJ
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admet-2338	395	3	40	40	NUM
admet-2338	395	4	]	]	PUNCT
admet-2338	395	5	s.	s.	PROPN
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admet-2338	395	7	,	,	PUNCT
admet-2338	395	8	s.h	s.h	PROPN
admet-2338	395	9	haidar	haidar	NOUN
admet-2338	395	10	,	,	PUNCT
admet-2338	395	11	x.	x.	PROPN
admet-2338	395	12	zhang	zhang	PROPN
admet-2338	395	13	,	,	PUNCT
admet-2338	395	14	w.	w.	PROPN
admet-2338	395	15	jiang	jiang	PROPN
admet-2338	395	16	,	,	PUNCT
admet-2338	395	17	c.	c.	PROPN
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admet-2338	395	19	,	,	PUNCT
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admet-2338	395	21	.	.	PROPN
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admet-2338	395	23	.	.	PUNCT
admet-2338	396	1	effect	effect	NOUN
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admet-2338	396	3	common	common	ADJ
admet-2338	396	4	excipients	excipient	NOUN
admet-2338	396	5	on	on	ADP
admet-2338	396	6	the	the	DET
admet-2338	396	7	oral	oral	ADJ
admet-2338	396	8	drug	drug	NOUN
admet-2338	396	9	absorption	absorption	NOUN
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admet-2338	396	12	classification	classification	NOUN
admet-2338	396	13	system	system	NOUN
admet-2338	396	14	class	class	NOUN
admet-2338	396	15	3	3	NUM
admet-2338	396	16	drugs	drug	NOUN
admet-2338	396	17	cimetidine	cimetidine	NOUN
admet-2338	396	18	and	and	CCONJ
admet-2338	396	19	acyclovir	acyclovir	PROPN
admet-2338	396	20	.	.	PUNCT
admet-2338	397	1	journal	journal	PROPN
admet-2338	397	2	of	of	ADP
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admet-2338	397	4	sciences	science	NOUN
admet-2338	397	5	105	105	NUM
admet-2338	397	6	(	(	PUNCT
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admet-2338	397	8	)	)	PUNCT
admet-2338	397	9	996	996	NUM
admet-2338	397	10	-	-	SYM
admet-2338	397	11	1005	1005	NUM
admet-2338	397	12	.	.	PUNCT
admet-2338	398	1	https://doi.org/10.1002/jps.24643	https://doi.org/10.1002/jps.24643	PROPN
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admet-2338	398	7	;	;	PUNCT
admet-2338	398	8	licensee	licensee	PROPN
admet-2338	398	9	iapc	iapc	PROPN
admet-2338	398	10	,	,	PUNCT
admet-2338	398	11	zagreb	zagreb	PROPN
admet-2338	398	12	,	,	PUNCT
admet-2338	398	13	croatia	croatia	PROPN
admet-2338	398	14	.	.	PUNCT
admet-2338	399	1	this	this	DET
admet-2338	399	2	article	article	NOUN
admet-2338	399	3	is	be	AUX
admet-2338	399	4	an	an	DET
admet-2338	399	5	open	open	ADJ
admet-2338	399	6	-	-	PUNCT
admet-2338	399	7	access	access	NOUN
admet-2338	399	8	article	article	NOUN
admet-2338	399	9	distributed	distribute	VERB
admet-2338	399	10	under	under	ADP
admet-2338	399	11	the	the	DET
admet-2338	399	12	terms	term	NOUN
admet-2338	399	13	and	and	CCONJ
admet-2338	399	14	conditions	condition	NOUN
admet-2338	399	15	of	of	ADP
admet-2338	399	16	the	the	DET
admet-2338	399	17	creative	creative	ADJ
admet-2338	399	18	commons	common	NOUN
admet-2338	399	19	attribution	attribution	NOUN
admet-2338	399	20	license	license	NOUN
admet-2338	399	21	(	(	PUNCT
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admet-2338	399	23	)	)	PUNCT
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admet-2338	399	28	https://sphinxsai.com/ptvol3/pt=66,nalini%20s,(822-831).pdf	https://sphinxsai.com/ptvol3/pt=66,nalini%20s,(822-831).pdf	NOUN
admet-2338	399	29	https://doi.org/10.1007/s12668-020-00800-7	https://doi.org/10.1007/s12668-020-00800-7	NUM
admet-2338	400	1	https://www.asiapharmaceutics.info/index.php/ajp/article/download/469/403/1305	https://www.asiapharmaceutics.info/index.php/ajp/article/download/469/403/1305	PROPN
admet-2338	400	2	https://doi.org/10.1691/ph.2020.9120	https://doi.org/10.1691/ph.2020.9120	PROPN
admet-2338	400	3	https://doi.org/10.1002/jps.24643	https://doi.org/10.1002/jps.24643	PROPN
admet-2338	400	4	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN