id	sid	tid	token	lemma	pos
admet-2366	1	1	investigation	investigation	NOUN
admet-2366	1	2	of	of	ADP
admet-2366	1	3	magnesium	magnesium	NOUN
admet-2366	1	4	aluminometasilicate	aluminometasilicate	NOUN
admet-2366	1	5	(	(	PUNCT
admet-2366	1	6	neusilin	neusilin	PROPN
admet-2366	1	7	us2	us2	PROPN
admet-2366	1	8	)	)	PUNCT
admet-2366	1	9	based	base	VERB
admet-2366	1	10	surface	surface	NOUN
admet-2366	1	11	solid	solid	ADJ
admet-2366	1	12	dispersion	dispersion	NOUN
admet-2366	1	13	of	of	ADP
admet-2366	1	14	sorafenib	sorafenib	NOUN
admet-2366	1	15	tosylate	tosylate	VERB
admet-2366	1	16	using	use	VERB
admet-2366	1	17	qbd	qbd	NOUN
admet-2366	1	18	approach	approach	NOUN
admet-2366	1	19	:	:	PUNCT
admet-2366	1	20	in	in	ADP
admet-2366	1	21	vitro	vitro	X
admet-2366	1	22	and	and	CCONJ
admet-2366	1	23	in	in	ADP
admet-2366	1	24	vivo	vivo	ADJ
admet-2366	1	25	pharmacokinetic	pharmacokinetic	ADJ
admet-2366	1	26	study	study	NOUN
admet-2366	1	27	doi	doi	NOUN
admet-2366	1	28	:	:	PUNCT
admet-2366	1	29	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PROPN
admet-2366	1	30	657	657	NUM
admet-2366	1	31	admet	admet	X
admet-2366	1	32	&	&	CCONJ
admet-2366	1	33	dmpk	dmpk	PROPN
admet-2366	1	34	12(4	12(4	PROPN
admet-2366	1	35	)	)	PUNCT
admet-2366	1	36	(	(	PUNCT
admet-2366	1	37	2024	2024	NUM
admet-2366	1	38	)	)	PUNCT
admet-2366	1	39	657	657	NUM
admet-2366	1	40	-	-	SYM
admet-2366	1	41	677	677	NUM
admet-2366	1	42	;	;	PUNCT
admet-2366	1	43	doi	doi	NOUN
admet-2366	1	44	:	:	PUNCT
admet-2366	1	45	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	ADJ
admet-2366	1	46	open	open	ADJ
admet-2366	1	47	access	access	NOUN
admet-2366	1	48	:	:	PUNCT
admet-2366	1	49	issn	issn	PROPN
admet-2366	1	50	:	:	PUNCT
admet-2366	1	51	1848	1848	NUM
admet-2366	1	52	-	-	SYM
admet-2366	1	53	7718	7718	NUM
admet-2366	1	54	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-2366	1	55	original	original	ADJ
admet-2366	1	56	scientific	scientific	ADJ
admet-2366	1	57	paper	paper	NOUN
admet-2366	1	58	optimizing	optimizing	NOUN
admet-2366	1	59	gefitinib	gefitinib	NOUN
admet-2366	1	60	nanoliposomes	nanoliposome	VERB
admet-2366	1	61	by	by	ADP
admet-2366	1	62	box	box	NOUN
admet-2366	1	63	-	-	PUNCT
admet-2366	1	64	behnken	behnken	VERB
admet-2366	1	65	design	design	NOUN
admet-2366	1	66	and	and	CCONJ
admet-2366	1	67	coating	coat	VERB
admet-2366	1	68	with	with	ADP
admet-2366	1	69	chitosan	chitosan	NOUN
admet-2366	1	70	:	:	PUNCT
admet-2366	1	71	a	a	DET
admet-2366	1	72	sequential	sequential	ADJ
admet-2366	1	73	approach	approach	NOUN
admet-2366	1	74	for	for	ADP
admet-2366	1	75	enhanced	enhanced	ADJ
admet-2366	1	76	drug	drug	NOUN
admet-2366	1	77	delivery	delivery	NOUN
admet-2366	1	78	seema	seema	PROPN
admet-2366	1	79	rohilla1	rohilla1	PROPN
admet-2366	1	80	,	,	PUNCT
admet-2366	1	81	rajendra	rajendra	PROPN
admet-2366	1	82	awasthi2	awasthi2	PROPN
admet-2366	1	83	,	,	PUNCT
admet-2366	1	84	ankur	ankur	PROPN
admet-2366	1	85	rohilla3	rohilla3	PROPN
admet-2366	1	86	,	,	PUNCT
admet-2366	1	87	sachin	sachin	PROPN
admet-2366	1	88	kumar	kumar	PROPN
admet-2366	1	89	singh4	singh4	PROPN
admet-2366	1	90	,	,	PUNCT
admet-2366	1	91	dinesh	dinesh	PROPN
admet-2366	1	92	kumar	kumar	PROPN
admet-2366	1	93	chellappan5	chellappan5	PROPN
admet-2366	1	94	,	,	PUNCT
admet-2366	1	95	kamal	kamal	PROPN
admet-2366	1	96	dua6,7	dua6,7	PROPN
admet-2366	1	97	and	and	CCONJ
admet-2366	1	98	harish	harish	PROPN
admet-2366	1	99	dureja7,8,9	dureja7,8,9	PROPN
admet-2366	1	100	,	,	PUNCT
admet-2366	1	101	*	*	PROPN
admet-2366	1	102	1geeta	1geeta	NUM
admet-2366	1	103	institute	institute	NOUN
admet-2366	1	104	of	of	ADP
admet-2366	1	105	pharmacy	pharmacy	PROPN
admet-2366	1	106	,	,	PUNCT
admet-2366	1	107	geeta	geeta	PROPN
admet-2366	1	108	university	university	PROPN
admet-2366	1	109	,	,	PUNCT
admet-2366	1	110	naultha	naultha	PROPN
admet-2366	1	111	,	,	PUNCT
admet-2366	1	112	panipat	panipat	PROPN
admet-2366	1	113	,	,	PUNCT
admet-2366	1	114	haryana	haryana	PROPN
admet-2366	1	115	,	,	PUNCT
admet-2366	1	116	india	india	PROPN
admet-2366	1	117	2department	2department	PROPN
admet-2366	1	118	of	of	ADP
admet-2366	1	119	pharmaceutical	pharmaceutical	NOUN
admet-2366	1	120	sciences	science	NOUN
admet-2366	1	121	,	,	PUNCT
admet-2366	1	122	school	school	NOUN
admet-2366	1	123	of	of	ADP
admet-2366	1	124	health	health	PROPN
admet-2366	1	125	sciences	sciences	PROPN
admet-2366	1	126	&	&	CCONJ
admet-2366	1	127	technology	technology	NOUN
admet-2366	1	128	,	,	PUNCT
admet-2366	1	129	upes	upe	NOUN
admet-2366	1	130	,	,	PUNCT
admet-2366	1	131	dehradun	dehradun	PROPN
admet-2366	1	132	,	,	PUNCT
admet-2366	1	133	uttarakhand	uttarakhand	PROPN
admet-2366	1	134	,	,	PUNCT
admet-2366	1	135	india	india	PROPN
admet-2366	1	136	3department	3department	PROPN
admet-2366	1	137	of	of	ADP
admet-2366	1	138	pharmaceutical	pharmaceutical	ADJ
admet-2366	1	139	sciences	science	NOUN
admet-2366	1	140	,	,	PUNCT
admet-2366	1	141	universal	universal	ADJ
admet-2366	1	142	group	group	NOUN
admet-2366	1	143	of	of	ADP
admet-2366	1	144	institutions	institution	NOUN
admet-2366	1	145	,	,	PUNCT
admet-2366	1	146	dera	dera	PROPN
admet-2366	1	147	bassi	bassi	PROPN
admet-2366	1	148	,	,	PUNCT
admet-2366	1	149	mohali	mohali	PROPN
admet-2366	1	150	,	,	PUNCT
admet-2366	1	151	punjab	punjab	PROPN
admet-2366	1	152	,	,	PUNCT
admet-2366	1	153	india	india	PROPN
admet-2366	1	154	4school	4school	PROPN
admet-2366	1	155	of	of	ADP
admet-2366	1	156	pharmaceutical	pharmaceutical	NOUN
admet-2366	1	157	sciences	science	NOUN
admet-2366	1	158	,	,	PUNCT
admet-2366	1	159	lovely	lovely	ADJ
admet-2366	1	160	professional	professional	ADJ
admet-2366	1	161	university	university	NOUN
admet-2366	1	162	,	,	PUNCT
admet-2366	1	163	phagwara	phagwara	ADJ
admet-2366	1	164	,	,	PUNCT
admet-2366	1	165	punjab	punjab	ADJ
admet-2366	1	166	,	,	PUNCT
admet-2366	1	167	india	india	PROPN
admet-2366	1	168	5department	5department	NUM
admet-2366	1	169	of	of	ADP
admet-2366	1	170	life	life	NOUN
admet-2366	1	171	sciences	science	NOUN
admet-2366	1	172	,	,	PUNCT
admet-2366	1	173	school	school	NOUN
admet-2366	1	174	of	of	ADP
admet-2366	1	175	pharmacy	pharmacy	NOUN
admet-2366	1	176	,	,	PUNCT
admet-2366	1	177	international	international	ADJ
admet-2366	1	178	medical	medical	ADJ
admet-2366	1	179	university	university	PROPN
admet-2366	1	180	,	,	PUNCT
admet-2366	1	181	bukit	bukit	PROPN
admet-2366	1	182	jalil	jalil	PROPN
admet-2366	1	183	,	,	PUNCT
admet-2366	1	184	kuala	kuala	PROPN
admet-2366	1	185	lumpur	lumpur	PROPN
admet-2366	1	186	,	,	PUNCT
admet-2366	1	187	malaysia	malaysia	PROPN
admet-2366	1	188	6discipline	6discipline	NUM
admet-2366	1	189	of	of	ADP
admet-2366	1	190	pharmacy	pharmacy	NOUN
admet-2366	1	191	,	,	PUNCT
admet-2366	1	192	graduate	graduate	NOUN
admet-2366	1	193	school	school	NOUN
admet-2366	1	194	of	of	ADP
admet-2366	1	195	health	health	NOUN
admet-2366	1	196	,	,	PUNCT
admet-2366	1	197	university	university	NOUN
admet-2366	1	198	of	of	ADP
admet-2366	1	199	technology	technology	PROPN
admet-2366	1	200	sydney	sydney	PROPN
admet-2366	1	201	,	,	PUNCT
admet-2366	1	202	nsw	nsw	PROPN
admet-2366	1	203	,	,	PUNCT
admet-2366	1	204	australia	australia	PROPN
admet-2366	1	205	7faculty	7faculty	NUM
admet-2366	1	206	of	of	ADP
admet-2366	1	207	health	health	NOUN
admet-2366	1	208	,	,	PUNCT
admet-2366	1	209	australian	australian	ADJ
admet-2366	1	210	research	research	NOUN
admet-2366	1	211	centre	centre	NOUN
admet-2366	1	212	in	in	ADP
admet-2366	1	213	complementary	complementary	ADJ
admet-2366	1	214	and	and	CCONJ
admet-2366	1	215	integrative	integrative	ADJ
admet-2366	1	216	medicine	medicine	NOUN
admet-2366	1	217	,	,	PUNCT
admet-2366	1	218	university	university	NOUN
admet-2366	1	219	of	of	ADP
admet-2366	1	220	technology	technology	PROPN
admet-2366	1	221	sydney	sydney	PROPN
admet-2366	1	222	,	,	PUNCT
admet-2366	1	223	ultimo	ultimo	PROPN
admet-2366	1	224	,	,	PUNCT
admet-2366	1	225	australia	australia	PROPN
admet-2366	1	226	8centre	8centre	NUM
admet-2366	1	227	for	for	ADP
admet-2366	1	228	research	research	NOUN
admet-2366	1	229	impact	impact	NOUN
admet-2366	1	230	&	&	CCONJ
admet-2366	1	231	outcome	outcome	PROPN
admet-2366	1	232	,	,	PUNCT
admet-2366	1	233	chitkara	chitkara	PROPN
admet-2366	1	234	college	college	NOUN
admet-2366	1	235	of	of	ADP
admet-2366	1	236	pharmacy	pharmacy	NOUN
admet-2366	1	237	,	,	PUNCT
admet-2366	1	238	chitkara	chitkara	ADJ
admet-2366	1	239	university	university	NOUN
admet-2366	1	240	,	,	PUNCT
admet-2366	1	241	rajpura	rajpura	NOUN
admet-2366	1	242	,	,	PUNCT
admet-2366	1	243	140401	140401	NUM
admet-2366	1	244	,	,	PUNCT
admet-2366	1	245	punjab	punjab	PROPN
admet-2366	1	246	,	,	PUNCT
admet-2366	1	247	india	india	PROPN
admet-2366	1	248	9department	9department	NUM
admet-2366	1	249	of	of	ADP
admet-2366	1	250	pharmaceutical	pharmaceutical	ADJ
admet-2366	1	251	sciences	science	NOUN
admet-2366	1	252	,	,	PUNCT
admet-2366	1	253	maharshi	maharshi	PROPN
admet-2366	1	254	dayanand	dayanand	PROPN
admet-2366	1	255	university	university	PROPN
admet-2366	1	256	,	,	PUNCT
admet-2366	1	257	rohtak	rohtak	PROPN
admet-2366	1	258	,	,	PUNCT
admet-2366	1	259	india	india	PROPN
admet-2366	1	260	*	*	PUNCT
admet-2366	1	261	corresponding	correspond	VERB
admet-2366	1	262	author	author	NOUN
admet-2366	1	263	:	:	PUNCT
admet-2366	1	264	e	e	NOUN
admet-2366	1	265	-	-	NOUN
admet-2366	1	266	mail	mail	NOUN
admet-2366	1	267	:	:	PUNCT
admet-2366	1	268	harishdureja@mdu.ac.in	harishdureja@mdu.ac.in	NOUN
admet-2366	1	269	;	;	PUNCT
admet-2366	1	270	tel	tel	PROPN
admet-2366	1	271	.	.	PUNCT
admet-2366	1	272	:	:	PUNCT
admet-2366	2	1	+91	+91	PROPN
admet-2366	2	2	-	-	PUNCT
admet-2366	2	3	9416357995	9416357995	NUM
admet-2366	2	4	received	receive	VERB
admet-2366	2	5	:	:	PUNCT
admet-2366	2	6	april	april	PROPN
admet-2366	2	7	25	25	NUM
admet-2366	2	8	,	,	PUNCT
admet-2366	2	9	2024	2024	NUM
admet-2366	2	10	;	;	PUNCT
admet-2366	2	11	revised	revise	VERB
admet-2366	2	12	:	:	PUNCT
admet-2366	2	13	july	july	PROPN
admet-2366	2	14	21	21	NUM
admet-2366	2	15	,	,	PUNCT
admet-2366	2	16	2024	2024	NUM
admet-2366	2	17	;	;	PUNCT
admet-2366	2	18	published	publish	VERB
admet-2366	2	19	:	:	PUNCT
admet-2366	2	20	july	july	PROPN
admet-2366	2	21	31	31	NUM
admet-2366	2	22	,	,	PUNCT
admet-2366	2	23	2024	2024	NUM
admet-2366	2	24	abstract	abstract	ADJ
admet-2366	2	25	background	background	NOUN
admet-2366	2	26	and	and	CCONJ
admet-2366	2	27	purpose	purpose	NOUN
admet-2366	2	28	:	:	PUNCT
admet-2366	2	29	this	this	DET
admet-2366	2	30	study	study	NOUN
admet-2366	2	31	aimed	aim	VERB
admet-2366	2	32	to	to	PART
admet-2366	2	33	improve	improve	VERB
admet-2366	2	34	the	the	DET
admet-2366	2	35	stability	stability	NOUN
admet-2366	2	36	and	and	CCONJ
admet-2366	2	37	prolonged	prolonged	ADJ
admet-2366	2	38	gefitinib	gefitinib	NOUN
admet-2366	2	39	release	release	NOUN
admet-2366	2	40	from	from	ADP
admet-2366	2	41	the	the	DET
admet-2366	2	42	nanoliposomes	nanoliposome	NOUN
admet-2366	2	43	.	.	PUNCT
admet-2366	3	1	experimental	experimental	ADJ
admet-2366	3	2	approach	approach	NOUN
admet-2366	3	3	:	:	PUNCT
admet-2366	3	4	nanoliposomes	nanoliposome	NOUN
admet-2366	3	5	were	be	AUX
admet-2366	3	6	prepared	prepare	VERB
admet-2366	3	7	by	by	ADP
admet-2366	3	8	reverse	reverse	NOUN
admet-2366	3	9	-	-	PUNCT
admet-2366	3	10	phase	phase	NOUN
admet-2366	3	11	evaporation	evaporation	NOUN
admet-2366	3	12	and	and	CCONJ
admet-2366	3	13	optimized	optimize	VERB
admet-2366	3	14	using	use	VERB
admet-2366	3	15	box	box	NOUN
admet-2366	3	16	-	-	PUNCT
admet-2366	3	17	behnken	behnken	VERB
admet-2366	3	18	design	design	NOUN
admet-2366	3	19	to	to	PART
admet-2366	3	20	investigate	investigate	VERB
admet-2366	3	21	the	the	DET
admet-2366	3	22	influence	influence	NOUN
admet-2366	3	23	of	of	ADP
admet-2366	3	24	sonication	sonication	NOUN
admet-2366	3	25	time	time	NOUN
admet-2366	3	26	(	(	PUNCT
admet-2366	3	27	x1	x1	PROPN
admet-2366	3	28	)	)	PUNCT
admet-2366	3	29	,	,	PUNCT
admet-2366	3	30	tween	tween	NOUN
admet-2366	3	31	80	80	NUM
admet-2366	3	32	/	/	SYM
admet-2366	3	33	soya	soya	NOUN
admet-2366	3	34	phosphatidylcholine	phosphatidylcholine	NOUN
admet-2366	3	35	ratio	ratio	NOUN
admet-2366	3	36	(	(	PUNCT
admet-2366	3	37	x2	x2	PROPN
admet-2366	3	38	)	)	PUNCT
admet-2366	3	39	,	,	PUNCT
admet-2366	3	40	and	and	CCONJ
admet-2366	3	41	cholesterol	cholesterol	NOUN
admet-2366	3	42	/	/	SYM
admet-2366	3	43	soya	soya	NOUN
admet-2366	3	44	phosphatidylcholine	phosphatidylcholine	NOUN
admet-2366	3	45	ratio	ratio	NOUN
admet-2366	3	46	(	(	PUNCT
admet-2366	3	47	x3	x3	ADJ
admet-2366	3	48	)	)	PUNCT
admet-2366	3	49	on	on	ADP
admet-2366	3	50	nanoliposomes	nanoliposome	NOUN
admet-2366	3	51	.	.	PUNCT
admet-2366	4	1	key	key	ADJ
admet-2366	4	2	results	result	NOUN
admet-2366	4	3	:	:	PUNCT
admet-2366	4	4	optimized	optimize	VERB
admet-2366	4	5	nanoliposomes	nanoliposome	NOUN
admet-2366	4	6	were	be	AUX
admet-2366	4	7	quasi	quasi	ADJ
admet-2366	4	8	-	-	ADJ
admet-2366	4	9	spherical	spherical	ADJ
admet-2366	4	10	shaped	shape	VERB
admet-2366	4	11	,	,	PUNCT
admet-2366	4	12	with	with	ADP
admet-2366	4	13	a	a	DET
admet-2366	4	14	mean	mean	ADJ
admet-2366	4	15	dimension	dimension	NOUN
admet-2366	4	16	of	of	ADP
admet-2366	4	17	93.2	93.2	NUM
admet-2366	4	18	nm	nm	NOUN
admet-2366	4	19	and	and	CCONJ
admet-2366	4	20	an	an	DET
admet-2366	4	21	encapsulation	encapsulation	NOUN
admet-2366	4	22	efficiency	efficiency	NOUN
admet-2366	4	23	of	of	ADP
admet-2366	4	24	87.56±0.17	87.56±0.17	NUM
admet-2366	4	25	%	%	NOUN
admet-2366	4	26	.	.	PUNCT
admet-2366	5	1	surface	surface	NOUN
admet-2366	5	2	decoration	decoration	NOUN
admet-2366	5	3	of	of	ADP
admet-2366	5	4	the	the	DET
admet-2366	5	5	optimized	optimize	VERB
admet-2366	5	6	batch	batch	NOUN
admet-2366	5	7	was	be	AUX
admet-2366	5	8	done	do	VERB
admet-2366	5	9	using	use	VERB
admet-2366	5	10	different	different	ADJ
admet-2366	5	11	concentrations	concentration	NOUN
admet-2366	5	12	of	of	ADP
admet-2366	5	13	chitosan	chitosan	NOUN
admet-2366	5	14	.	.	PUNCT
admet-2366	6	1	the	the	DET
admet-2366	6	2	optimal	optimal	ADJ
admet-2366	6	3	chitosan	chitosan	ADJ
admet-2366	6	4	concentration	concentration	NOUN
admet-2366	6	5	required	require	VERB
admet-2366	6	6	to	to	PART
admet-2366	6	7	adorn	adorn	VERB
admet-2366	6	8	the	the	DET
admet-2366	6	9	nanoliposome	nanoliposome	NOUN
admet-2366	6	10	surface	surface	NOUN
admet-2366	6	11	was	be	AUX
admet-2366	6	12	0.01	0.01	NUM
admet-2366	6	13	%	%	NOUN
admet-2366	6	14	.	.	PUNCT
admet-2366	7	1	in	in	ADP
admet-2366	7	2	comparison	comparison	NOUN
admet-2366	7	3	to	to	ADP
admet-2366	7	4	unadorned	unadorned	ADJ
admet-2366	7	5	nanoliposomes	nanoliposome	NOUN
admet-2366	7	6	(	(	PUNCT
admet-2366	7	7	82.16±0.65	82.16±0.65	NUM
admet-2366	7	8	%	%	NOUN
admet-2366	7	9	)	)	PUNCT
admet-2366	7	10	,	,	PUNCT
admet-2366	7	11	adorned	adorn	VERB
admet-2366	7	12	nanoliposomes	nanoliposomes	ADV
admet-2366	7	13	(	(	PUNCT
admet-2366	7	14	78.04±0.35	78.04±0.35	NUM
admet-2366	7	15	%	%	NOUN
admet-2366	7	16	)	)	PUNCT
admet-2366	7	17	released	release	VERB
admet-2366	7	18	the	the	DET
admet-2366	7	19	drug	drug	NOUN
admet-2366	7	20	consistently	consistently	ADV
admet-2366	7	21	over	over	ADP
admet-2366	7	22	24	24	NUM
admet-2366	7	23	h	h	NOUN
admet-2366	7	24	via	via	ADP
admet-2366	7	25	fickian	fickian	ADJ
admet-2366	7	26	diffusion	diffusion	NOUN
admet-2366	7	27	.	.	PUNCT
admet-2366	8	1	the	the	DET
admet-2366	8	2	ic50	ic50	PROPN
admet-2366	8	3	values	value	NOUN
admet-2366	8	4	for	for	ADP
admet-2366	8	5	surface	surface	NOUN
admet-2366	8	6	-	-	PUNCT
admet-2366	8	7	adorned	adorn	VERB
admet-2366	8	8	nanoliposomes	nanoliposome	NOUN
admet-2366	8	9	in	in	ADP
admet-2366	8	10	a549	a549	PROPN
admet-2366	8	11	and	and	CCONJ
admet-2366	8	12	h1299	h1299	NUM
admet-2366	8	13	cells	cell	NOUN
admet-2366	8	14	were	be	AUX
admet-2366	8	15	6.53±0.75	6.53±0.75	NOUN
admet-2366	8	16	and	and	CCONJ
admet-2366	8	17	4.73±0.46	4.73±0.46	NUM
admet-2366	8	18	µm	µm	NOUN
admet-2366	8	19	,	,	PUNCT
admet-2366	8	20	respectively	respectively	ADV
admet-2366	8	21	.	.	PUNCT
admet-2366	9	1	cytotoxicity	cytotoxicity	NOUN
admet-2366	9	2	of	of	ADP
admet-2366	9	3	the	the	DET
admet-2366	9	4	surface	surface	NOUN
admet-2366	9	5	-	-	PUNCT
admet-2366	9	6	decorated	decorate	VERB
admet-2366	9	7	nanoliposomes	nanoliposome	NOUN
admet-2366	9	8	may	may	AUX
admet-2366	9	9	be	be	AUX
admet-2366	9	10	due	due	ADJ
admet-2366	9	11	to	to	ADP
admet-2366	9	12	their	their	PRON
admet-2366	9	13	higher	high	ADJ
admet-2366	9	14	zeta	zeta	NOUN
admet-2366	9	15	potential	potential	ADJ
admet-2366	9	16	and	and	CCONJ
admet-2366	9	17	prolonged	prolonged	ADJ
admet-2366	9	18	drug	drug	NOUN
admet-2366	9	19	release	release	NOUN
admet-2366	9	20	.	.	PUNCT
admet-2366	10	1	at	at	ADP
admet-2366	10	2	the	the	DET
admet-2366	10	3	end	end	NOUN
admet-2366	10	4	of	of	ADP
admet-2366	10	5	the	the	DET
admet-2366	10	6	sixth	sixth	ADJ
admet-2366	10	7	month	month	NOUN
admet-2366	10	8	,	,	PUNCT
admet-2366	10	9	the	the	DET
admet-2366	10	10	samples	sample	NOUN
admet-2366	10	11	stored	store	VERB
admet-2366	10	12	at	at	ADP
admet-2366	10	13	4	4	NUM
admet-2366	10	14	°	°	NOUN
admet-2366	10	15	c	c	NOUN
admet-2366	10	16	were	be	AUX
admet-2366	10	17	more	more	ADV
admet-2366	10	18	stable	stable	ADJ
admet-2366	10	19	than	than	ADP
admet-2366	10	20	those	those	PRON
admet-2366	10	21	stored	store	VERB
admet-2366	10	22	at	at	ADP
admet-2366	10	23	25	25	NUM
admet-2366	10	24	°	°	NOUN
admet-2366	10	25	c	c	NOUN
admet-2366	10	26	and	and	CCONJ
admet-2366	10	27	45	45	NUM
admet-2366	10	28	°	°	NOUN
admet-2366	10	29	c	c	NOUN
admet-2366	10	30	.	.	PUNCT
admet-2366	11	1	the	the	DET
admet-2366	11	2	stability	stability	NOUN
admet-2366	11	3	of	of	ADP
admet-2366	11	4	plain	plain	ADJ
admet-2366	11	5	nanoliposomes	nanoliposome	NOUN
admet-2366	11	6	has	have	AUX
admet-2366	11	7	increased	increase	VERB
admet-2366	11	8	after	after	ADP
admet-2366	11	9	chitosan	chitosan	NOUN
admet-2366	11	10	coating	coating	NOUN
admet-2366	11	11	.	.	PUNCT
admet-2366	12	1	thus	thus	ADV
admet-2366	12	2	,	,	PUNCT
admet-2366	12	3	by	by	ADP
admet-2366	12	4	using	use	VERB
admet-2366	12	5	different	different	ADJ
admet-2366	12	6	concentrations	concentration	NOUN
admet-2366	12	7	of	of	ADP
admet-2366	12	8	chitosan	chitosan	ADJ
admet-2366	12	9	solution	solution	NOUN
admet-2366	12	10	as	as	ADP
admet-2366	12	11	coating	coating	NOUN
admet-2366	12	12	material	material	NOUN
admet-2366	12	13	,	,	PUNCT
admet-2366	12	14	we	we	PRON
admet-2366	12	15	can	can	AUX
admet-2366	12	16	develop	develop	VERB
admet-2366	12	17	a	a	DET
admet-2366	12	18	suitable	suitable	ADJ
admet-2366	12	19	sustained	sustained	ADJ
admet-2366	12	20	drug	drug	NOUN
admet-2366	12	21	-	-	PUNCT
admet-2366	12	22	release	release	NOUN
admet-2366	12	23	surface	surface	NOUN
admet-2366	12	24	-	-	PUNCT
admet-2366	12	25	adorned	adorn	VERB
admet-2366	12	26	nanoliposomal	nanoliposomal	ADJ
admet-2366	12	27	formulation	formulation	NOUN
admet-2366	12	28	.	.	PUNCT
admet-2366	13	1	conclusion	conclusion	NOUN
admet-2366	13	2	:	:	PUNCT
admet-2366	13	3	the	the	DET
admet-2366	13	4	developed	develop	VERB
admet-2366	13	5	nanoliposomes	nanoliposome	NOUN
admet-2366	13	6	may	may	AUX
admet-2366	13	7	offer	offer	VERB
admet-2366	13	8	a	a	DET
admet-2366	13	9	new	new	ADJ
admet-2366	13	10	path	path	NOUN
admet-2366	13	11	for	for	ADP
admet-2366	13	12	melanoma	melanoma	NOUN
admet-2366	13	13	clinics	clinic	NOUN
admet-2366	13	14	.	.	PUNCT
admet-2366	14	1	©	©	ADP
admet-2366	14	2	2024	2024	NUM
admet-2366	14	3	by	by	ADP
admet-2366	14	4	the	the	DET
admet-2366	14	5	authors	author	NOUN
admet-2366	14	6	.	.	PUNCT
admet-2366	15	1	this	this	DET
admet-2366	15	2	article	article	NOUN
admet-2366	15	3	is	be	AUX
admet-2366	15	4	an	an	DET
admet-2366	15	5	open	open	ADJ
admet-2366	15	6	-	-	PUNCT
admet-2366	15	7	access	access	NOUN
admet-2366	15	8	article	article	NOUN
admet-2366	15	9	distributed	distribute	VERB
admet-2366	15	10	under	under	ADP
admet-2366	15	11	the	the	DET
admet-2366	15	12	terms	term	NOUN
admet-2366	15	13	and	and	CCONJ
admet-2366	15	14	conditions	condition	NOUN
admet-2366	15	15	of	of	ADP
admet-2366	15	16	the	the	DET
admet-2366	15	17	creative	creative	ADJ
admet-2366	15	18	commons	common	NOUN
admet-2366	15	19	attribution	attribution	NOUN
admet-2366	15	20	license	license	NOUN
admet-2366	15	21	(	(	PUNCT
admet-2366	15	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2366	15	23	)	)	PUNCT
admet-2366	15	24	.	.	PUNCT
admet-2366	16	1	keywords	keyword	NOUN
admet-2366	16	2	liposomes	liposome	NOUN
admet-2366	16	3	;	;	PUNCT
admet-2366	16	4	response	response	NOUN
admet-2366	16	5	surface	surface	NOUN
admet-2366	16	6	methodology	methodology	NOUN
admet-2366	16	7	;	;	PUNCT
admet-2366	16	8	pulmonary	pulmonary	ADJ
admet-2366	16	9	cancer	cancer	NOUN
admet-2366	16	10	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	VERB
admet-2366	17	1	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	DET
admet-2366	17	2	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-2366	17	3	mailto:harishdureja@mdu.ac.in	mailto:harishdureja@mdu.ac.in	ADV
admet-2366	17	4	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2366	17	5	s.	s.	PROPN
admet-2366	17	6	rohilla	rohilla	PROPN
admet-2366	17	7	et	et	PROPN
admet-2366	17	8	al	al	PROPN
admet-2366	17	9	.	.	PROPN
admet-2366	17	10	admet	admet	PROPN
admet-2366	17	11	&	&	CCONJ
admet-2366	17	12	dmpk	dmpk	PROPN
admet-2366	17	13	12(4	12(4	PROPN
admet-2366	17	14	)	)	PUNCT
admet-2366	17	15	(	(	PUNCT
admet-2366	17	16	2024	2024	NUM
admet-2366	17	17	)	)	PUNCT
admet-2366	17	18	657	657	NUM
admet-2366	17	19	-	-	SYM
admet-2366	17	20	677	677	NUM
admet-2366	17	21	658	658	NUM
admet-2366	17	22	introduction	introduction	NOUN
admet-2366	17	23	cancer	cancer	NOUN
admet-2366	17	24	is	be	AUX
admet-2366	17	25	a	a	DET
admet-2366	17	26	group	group	NOUN
admet-2366	17	27	of	of	ADP
admet-2366	17	28	diseases	disease	NOUN
admet-2366	17	29	defined	define	VERB
admet-2366	17	30	by	by	ADP
admet-2366	17	31	the	the	DET
admet-2366	17	32	uncontrolled	uncontrolled	ADJ
admet-2366	17	33	proliferation	proliferation	NOUN
admet-2366	17	34	and	and	CCONJ
admet-2366	17	35	metastasis	metastasis	NOUN
admet-2366	17	36	of	of	ADP
admet-2366	17	37	abnormal	abnormal	ADJ
admet-2366	17	38	cells	cell	NOUN
admet-2366	17	39	.	.	PUNCT
admet-2366	18	1	it	it	PRON
admet-2366	18	2	is	be	AUX
admet-2366	18	3	difficult	difficult	ADJ
admet-2366	18	4	to	to	PART
admet-2366	18	5	understand	understand	VERB
admet-2366	18	6	the	the	DET
admet-2366	18	7	molecular	molecular	ADJ
admet-2366	18	8	causes	cause	NOUN
admet-2366	18	9	of	of	ADP
admet-2366	18	10	drug	drug	NOUN
admet-2366	18	11	resistance	resistance	NOUN
admet-2366	18	12	,	,	PUNCT
admet-2366	18	13	early	early	ADJ
admet-2366	18	14	diagnosis	diagnosis	NOUN
admet-2366	18	15	,	,	PUNCT
admet-2366	18	16	multimodal	multimodal	NOUN
admet-2366	18	17	psychoanalysis	psychoanalysis	NOUN
admet-2366	18	18	,	,	PUNCT
admet-2366	18	19	and	and	CCONJ
admet-2366	18	20	the	the	DET
admet-2366	18	21	reasons	reason	NOUN
admet-2366	18	22	why	why	SCONJ
admet-2366	18	23	most	most	ADJ
admet-2366	18	24	treatments	treatment	NOUN
admet-2366	18	25	for	for	ADP
admet-2366	18	26	metastatic	metastatic	ADJ
admet-2366	18	27	disease	disease	NOUN
admet-2366	18	28	do	do	AUX
admet-2366	18	29	not	not	PART
admet-2366	18	30	work	work	VERB
admet-2366	18	31	[	[	X
admet-2366	18	32	1	1	NUM
admet-2366	18	33	]	]	PUNCT
admet-2366	18	34	.	.	PUNCT
admet-2366	19	1	pulmonary	pulmonary	ADJ
admet-2366	19	2	cancer	cancer	NOUN
admet-2366	19	3	is	be	AUX
admet-2366	19	4	the	the	DET
admet-2366	19	5	second	second	ADJ
admet-2366	19	6	most	most	ADV
admet-2366	19	7	tumours	tumours	ADJ
admet-2366	19	8	,	,	PUNCT
admet-2366	19	9	responsible	responsible	ADJ
admet-2366	19	10	for	for	ADP
admet-2366	19	11	the	the	DET
admet-2366	19	12	deaths	death	NOUN
admet-2366	19	13	of	of	ADP
admet-2366	19	14	both	both	DET
admet-2366	19	15	men	man	NOUN
admet-2366	19	16	and	and	CCONJ
admet-2366	19	17	women	woman	NOUN
admet-2366	19	18	.	.	PUNCT
admet-2366	20	1	imaging	imaging	NOUN
admet-2366	20	2	techniques	technique	NOUN
admet-2366	20	3	such	such	ADJ
admet-2366	20	4	as	as	ADP
admet-2366	20	5	magnetic	magnetic	ADJ
admet-2366	20	6	resonance	resonance	NOUN
admet-2366	20	7	imaging	imaging	NOUN
admet-2366	20	8	(	(	PUNCT
admet-2366	20	9	mri	mri	NOUN
admet-2366	20	10	)	)	PUNCT
admet-2366	20	11	,	,	PUNCT
admet-2366	20	12	bone	bone	NOUN
admet-2366	20	13	scan	scan	NOUN
admet-2366	20	14	,	,	PUNCT
admet-2366	20	15	computed	compute	VERB
admet-2366	20	16	tomography	tomography	NOUN
admet-2366	20	17	(	(	PUNCT
admet-2366	20	18	ct	ct	PROPN
admet-2366	20	19	)	)	PUNCT
admet-2366	20	20	,	,	PUNCT
admet-2366	20	21	x	x	X
admet-2366	20	22	-	-	PUNCT
admet-2366	20	23	ray	ray	NOUN
admet-2366	20	24	,	,	PUNCT
admet-2366	20	25	positron	positron	NOUN
admet-2366	20	26	emission	emission	NOUN
admet-2366	20	27	tomography	tomography	NOUN
admet-2366	20	28	(	(	PUNCT
admet-2366	20	29	pet	pet	NOUN
admet-2366	20	30	)	)	PUNCT
admet-2366	20	31	,	,	PUNCT
admet-2366	20	32	and	and	CCONJ
admet-2366	20	33	combined	combine	VERB
admet-2366	20	34	pet	pet	NOUN
admet-2366	20	35	-	-	PUNCT
admet-2366	20	36	ct	ct	NOUN
admet-2366	20	37	scan	scan	NOUN
admet-2366	20	38	are	be	AUX
admet-2366	20	39	used	use	VERB
admet-2366	20	40	to	to	PART
admet-2366	20	41	diagnose	diagnose	VERB
admet-2366	20	42	lung	lung	NOUN
admet-2366	20	43	cancer	cancer	NOUN
admet-2366	20	44	[	[	X
admet-2366	20	45	2	2	NUM
admet-2366	20	46	]	]	PUNCT
admet-2366	20	47	.	.	PUNCT
admet-2366	21	1	a	a	DET
admet-2366	21	2	combined	combine	VERB
admet-2366	21	3	pet	pet	NOUN
admet-2366	21	4	-	-	PUNCT
admet-2366	21	5	ct	ct	NOUN
admet-2366	21	6	scan	scan	NOUN
admet-2366	21	7	is	be	AUX
admet-2366	21	8	the	the	DET
admet-2366	21	9	standard	standard	ADJ
admet-2366	21	10	procedure	procedure	NOUN
admet-2366	21	11	among	among	ADP
admet-2366	21	12	all	all	DET
admet-2366	21	13	imaging	imaging	NOUN
admet-2366	21	14	tools	tool	NOUN
admet-2366	21	15	for	for	ADP
admet-2366	21	16	assessing	assess	VERB
admet-2366	21	17	the	the	DET
admet-2366	21	18	size	size	NOUN
admet-2366	21	19	and	and	CCONJ
admet-2366	21	20	location	location	NOUN
admet-2366	21	21	of	of	ADP
admet-2366	21	22	lung	lung	NOUN
admet-2366	21	23	tumors	tumor	NOUN
admet-2366	21	24	,	,	PUNCT
admet-2366	21	25	estimating	estimate	VERB
admet-2366	21	26	an	an	DET
admet-2366	21	27	accurate	accurate	ADJ
admet-2366	21	28	level	level	NOUN
admet-2366	21	29	of	of	ADP
admet-2366	21	30	illness	illness	NOUN
admet-2366	21	31	,	,	PUNCT
admet-2366	21	32	and	and	CCONJ
admet-2366	21	33	identifying	identify	VERB
admet-2366	21	34	indeterminate	indeterminate	ADJ
admet-2366	21	35	lung	lung	NOUN
admet-2366	21	36	nodules	nodule	NOUN
admet-2366	21	37	[	[	X
admet-2366	21	38	3,4	3,4	NUM
admet-2366	21	39	]	]	PUNCT
admet-2366	21	40	.	.	PUNCT
admet-2366	22	1	in	in	ADP
admet-2366	22	2	addition	addition	NOUN
admet-2366	22	3	to	to	ADP
admet-2366	22	4	early	early	ADJ
admet-2366	22	5	detection	detection	NOUN
admet-2366	22	6	of	of	ADP
admet-2366	22	7	lung	lung	NOUN
admet-2366	22	8	cancers	cancer	NOUN
admet-2366	22	9	,	,	PUNCT
admet-2366	22	10	appropriate	appropriate	ADJ
admet-2366	22	11	therapeutic	therapeutic	ADJ
admet-2366	22	12	treatment	treatment	NOUN
admet-2366	22	13	is	be	AUX
admet-2366	22	14	required	require	VERB
admet-2366	22	15	to	to	PART
admet-2366	22	16	cure	cure	VERB
admet-2366	22	17	them	they	PRON
admet-2366	22	18	.	.	PUNCT
admet-2366	23	1	treatment	treatment	NOUN
admet-2366	23	2	options	option	NOUN
admet-2366	23	3	for	for	ADP
admet-2366	23	4	lung	lung	NOUN
admet-2366	23	5	cancer	cancer	NOUN
admet-2366	23	6	include	include	VERB
admet-2366	23	7	surgery	surgery	NOUN
admet-2366	23	8	,	,	PUNCT
admet-2366	23	9	radiosurgery	radiosurgery	NOUN
admet-2366	23	10	,	,	PUNCT
admet-2366	23	11	radiotherapy	radiotherapy	NOUN
admet-2366	23	12	,	,	PUNCT
admet-2366	23	13	chemotherapy	chemotherapy	NOUN
admet-2366	23	14	,	,	PUNCT
admet-2366	23	15	and	and	CCONJ
admet-2366	23	16	immunotherapy	immunotherapy	NOUN
admet-2366	23	17	,	,	PUNCT
admet-2366	23	18	depending	depend	VERB
admet-2366	23	19	on	on	ADP
admet-2366	23	20	the	the	DET
admet-2366	23	21	stage	stage	NOUN
admet-2366	23	22	,	,	PUNCT
admet-2366	23	23	histological	histological	ADJ
admet-2366	23	24	type	type	NOUN
admet-2366	23	25	,	,	PUNCT
admet-2366	23	26	and	and	CCONJ
admet-2366	23	27	patient	patient	NOUN
admet-2366	23	28	's	's	PART
admet-2366	23	29	function	function	NOUN
admet-2366	23	30	.	.	PUNCT
admet-2366	24	1	radiation	radiation	NOUN
admet-2366	24	2	and	and	CCONJ
admet-2366	24	3	chemotherapy	chemotherapy	NOUN
admet-2366	24	4	can	can	AUX
admet-2366	24	5	replace	replace	VERB
admet-2366	24	6	surgery	surgery	NOUN
admet-2366	24	7	[	[	X
admet-2366	24	8	5	5	NUM
admet-2366	24	9	]	]	PUNCT
admet-2366	24	10	.	.	PUNCT
admet-2366	25	1	antagonism	antagonism	NOUN
admet-2366	25	2	of	of	ADP
admet-2366	25	3	the	the	DET
admet-2366	25	4	epidermal	epidermal	ADJ
admet-2366	25	5	growth	growth	NOUN
admet-2366	25	6	factor	factor	NOUN
admet-2366	25	7	receptor	receptor	NOUN
admet-2366	25	8	(	(	PUNCT
admet-2366	25	9	egfr	egfr	X
admet-2366	25	10	)	)	PUNCT
admet-2366	25	11	in	in	ADP
admet-2366	25	12	cancer	cancer	NOUN
admet-2366	25	13	cells	cell	NOUN
admet-2366	25	14	disrupts	disrupt	VERB
admet-2366	25	15	normal	normal	ADJ
admet-2366	25	16	epithelial	epithelial	ADJ
admet-2366	25	17	endorsement	endorsement	NOUN
admet-2366	25	18	and	and	CCONJ
admet-2366	25	19	succession	succession	NOUN
admet-2366	25	20	,	,	PUNCT
admet-2366	25	21	limiting	limit	VERB
admet-2366	25	22	normal	normal	ADJ
admet-2366	25	23	cell	cell	NOUN
admet-2366	25	24	transformation	transformation	NOUN
admet-2366	25	25	into	into	ADP
admet-2366	25	26	persistent	persistent	ADJ
admet-2366	25	27	and	and	CCONJ
admet-2366	25	28	metastatic	metastatic	ADJ
admet-2366	25	29	cancer	cancer	NOUN
admet-2366	25	30	cells	cell	NOUN
admet-2366	25	31	via	via	ADP
admet-2366	25	32	dysplasia	dysplasia	NOUN
admet-2366	25	33	to	to	ADP
admet-2366	25	34	high	high	ADJ
admet-2366	25	35	-	-	PUNCT
admet-2366	25	36	grade	grade	NOUN
admet-2366	25	37	prostatic	prostatic	ADJ
admet-2366	25	38	intraepithelial	intraepithelial	ADJ
admet-2366	25	39	neoplasia	neoplasia	NOUN
admet-2366	25	40	(	(	PUNCT
admet-2366	25	41	hgpin	hgpin	NOUN
admet-2366	25	42	)	)	PUNCT
admet-2366	26	1	[	[	X
admet-2366	26	2	6	6	NUM
admet-2366	26	3	-	-	SYM
admet-2366	26	4	8	8	NUM
admet-2366	26	5	]	]	PUNCT
admet-2366	26	6	.	.	PUNCT
admet-2366	27	1	gefitinib	gefitinib	NOUN
admet-2366	27	2	is	be	AUX
admet-2366	27	3	a	a	DET
admet-2366	27	4	low	low	ADJ
admet-2366	27	5	-	-	PUNCT
admet-2366	27	6	molecular	molecular	ADJ
admet-2366	27	7	-	-	PUNCT
admet-2366	27	8	weight	weight	NOUN
admet-2366	27	9	anilinoquinazoline	anilinoquinazoline	NOUN
admet-2366	27	10	derivative	derivative	NOUN
admet-2366	27	11	that	that	PRON
admet-2366	27	12	treats	treat	VERB
admet-2366	27	13	pulmonary	pulmonary	ADJ
admet-2366	27	14	cancer	cancer	NOUN
admet-2366	27	15	[	[	X
admet-2366	27	16	8,9	8,9	NUM
admet-2366	27	17	]	]	PUNCT
admet-2366	27	18	.	.	PUNCT
admet-2366	28	1	gefitinib	gefitinib	NOUN
admet-2366	28	2	binds	bind	VERB
admet-2366	28	3	to	to	PART
admet-2366	28	4	egfrs	egfrs	VERB
admet-2366	28	5	to	to	PART
admet-2366	28	6	inhibit	inhibit	VERB
admet-2366	28	7	tyrosine	tyrosine	PROPN
admet-2366	28	8	kinase	kinase	PROPN
admet-2366	28	9	activation	activation	NOUN
admet-2366	28	10	[	[	X
admet-2366	28	11	10,11	10,11	NOUN
admet-2366	28	12	]	]	X
admet-2366	28	13	.	.	PUNCT
admet-2366	29	1	due	due	ADP
admet-2366	29	2	to	to	ADP
admet-2366	29	3	its	its	PRON
admet-2366	29	4	poor	poor	ADJ
admet-2366	29	5	aqueous	aqueous	ADJ
admet-2366	29	6	solubility	solubility	NOUN
admet-2366	29	7	and	and	CCONJ
admet-2366	29	8	high	high	ADJ
admet-2366	29	9	permeability	permeability	NOUN
admet-2366	29	10	,	,	PUNCT
admet-2366	29	11	it	it	PRON
admet-2366	29	12	falls	fall	VERB
admet-2366	29	13	under	under	ADP
admet-2366	29	14	class	class	PROPN
admet-2366	29	15	ii	ii	PROPN
admet-2366	29	16	of	of	ADP
admet-2366	29	17	the	the	DET
admet-2366	29	18	biopharmaceutical	biopharmaceutical	ADJ
admet-2366	29	19	classification	classification	NOUN
admet-2366	29	20	system	system	NOUN
admet-2366	29	21	(	(	PUNCT
admet-2366	29	22	bcs	bcs	NOUN
admet-2366	29	23	)	)	PUNCT
admet-2366	30	1	[	[	X
admet-2366	30	2	12	12	NUM
admet-2366	30	3	]	]	PUNCT
admet-2366	30	4	.	.	PUNCT
admet-2366	31	1	low	low	ADJ
admet-2366	31	2	aqueous	aqueous	ADJ
admet-2366	31	3	solubility	solubility	NOUN
admet-2366	31	4	limits	limit	VERB
admet-2366	31	5	gefitinib	gefitinib	NOUN
admet-2366	31	6	's	's	PART
admet-2366	31	7	oral	oral	ADJ
admet-2366	31	8	absorption	absorption	NOUN
admet-2366	31	9	.	.	PUNCT
admet-2366	32	1	increasing	increase	VERB
admet-2366	32	2	solubility	solubility	NOUN
admet-2366	32	3	and	and	CCONJ
admet-2366	32	4	dissolution	dissolution	NOUN
admet-2366	32	5	could	could	AUX
admet-2366	32	6	boost	boost	VERB
admet-2366	32	7	bioavailability	bioavailability	NOUN
admet-2366	32	8	[	[	PUNCT
admet-2366	32	9	13	13	NUM
admet-2366	32	10	-	-	SYM
admet-2366	32	11	16	16	NUM
admet-2366	32	12	]	]	PUNCT
admet-2366	32	13	.	.	PUNCT
admet-2366	33	1	to	to	PART
admet-2366	33	2	improve	improve	VERB
admet-2366	33	3	the	the	DET
admet-2366	33	4	solubility	solubility	NOUN
admet-2366	33	5	and	and	CCONJ
admet-2366	33	6	oral	oral	ADJ
admet-2366	33	7	bioavailability	bioavailability	NOUN
admet-2366	33	8	of	of	ADP
admet-2366	33	9	poorly	poorly	ADV
admet-2366	33	10	water	water	NOUN
admet-2366	33	11	-	-	PUNCT
admet-2366	33	12	soluble	soluble	ADJ
admet-2366	33	13	drugs	drug	NOUN
admet-2366	33	14	,	,	PUNCT
admet-2366	33	15	different	different	ADJ
admet-2366	33	16	approaches	approach	NOUN
admet-2366	33	17	were	be	AUX
admet-2366	33	18	used	use	VERB
admet-2366	33	19	[	[	PUNCT
admet-2366	33	20	6,7,17	6,7,17	NUM
admet-2366	33	21	]	]	PUNCT
admet-2366	33	22	.	.	PUNCT
admet-2366	34	1	the	the	DET
admet-2366	34	2	amphiphilic	amphiphilic	ADJ
admet-2366	34	3	nature	nature	NOUN
admet-2366	34	4	of	of	ADP
admet-2366	34	5	liposomes	liposome	NOUN
admet-2366	34	6	(	(	PUNCT
admet-2366	34	7	having	have	VERB
admet-2366	34	8	both	both	CCONJ
admet-2366	34	9	hydrophilic	hydrophilic	ADJ
admet-2366	34	10	and	and	CCONJ
admet-2366	34	11	hydrophobic	hydrophobic	NOUN
admet-2366	34	12	parts	part	NOUN
admet-2366	34	13	)	)	PUNCT
admet-2366	34	14	allows	allow	VERB
admet-2366	34	15	them	they	PRON
admet-2366	34	16	to	to	PART
admet-2366	34	17	interact	interact	VERB
admet-2366	34	18	with	with	ADP
admet-2366	34	19	poorly	poorly	ADV
admet-2366	34	20	soluble	soluble	ADJ
admet-2366	34	21	drugs	drug	NOUN
admet-2366	34	22	and	and	CCONJ
admet-2366	34	23	water	water	NOUN
admet-2366	34	24	,	,	PUNCT
admet-2366	34	25	creating	create	VERB
admet-2366	34	26	a	a	DET
admet-2366	34	27	microenvironment	microenvironment	NOUN
admet-2366	34	28	that	that	PRON
admet-2366	34	29	enhances	enhance	VERB
admet-2366	34	30	the	the	DET
admet-2366	34	31	solubility	solubility	NOUN
admet-2366	34	32	of	of	ADP
admet-2366	34	33	hydrophobic	hydrophobic	NOUN
admet-2366	34	34	drugs	drug	NOUN
admet-2366	34	35	.	.	PUNCT
admet-2366	35	1	the	the	DET
admet-2366	35	2	lipid	lipid	NOUN
admet-2366	35	3	environment	environment	NOUN
admet-2366	35	4	within	within	ADP
admet-2366	35	5	the	the	DET
admet-2366	35	6	hydrocarbon	hydrocarbon	NOUN
admet-2366	35	7	chain	chain	NOUN
admet-2366	35	8	region	region	NOUN
admet-2366	35	9	of	of	ADP
admet-2366	35	10	the	the	DET
admet-2366	35	11	lipid	lipid	ADJ
admet-2366	35	12	bilayer	bilayer	NOUN
admet-2366	35	13	of	of	ADP
admet-2366	35	14	nanoliposomes	nanoliposome	NOUN
admet-2366	35	15	can	can	AUX
admet-2366	35	16	solubilize	solubilize	VERB
admet-2366	35	17	hydrophobic	hydrophobic	NOUN
admet-2366	35	18	drugs	drug	NOUN
admet-2366	35	19	like	like	ADP
admet-2366	35	20	gefitinib	gefitinib	NOUN
admet-2366	35	21	,	,	PUNCT
admet-2366	35	22	effectively	effectively	ADV
admet-2366	35	23	increasing	increase	VERB
admet-2366	35	24	its	its	PRON
admet-2366	35	25	aqueous	aqueous	ADJ
admet-2366	35	26	solubility	solubility	NOUN
admet-2366	35	27	.	.	PUNCT
admet-2366	36	1	thus	thus	ADV
admet-2366	36	2	,	,	PUNCT
admet-2366	36	3	nanoliposomes	nanoliposome	NOUN
admet-2366	36	4	improve	improve	VERB
admet-2366	36	5	the	the	DET
admet-2366	36	6	solubility	solubility	NOUN
admet-2366	36	7	of	of	ADP
admet-2366	36	8	poorly	poorly	ADV
admet-2366	36	9	soluble	soluble	ADJ
admet-2366	36	10	drugs	drug	NOUN
admet-2366	36	11	like	like	ADP
admet-2366	36	12	gefitinib	gefitinib	NOUN
admet-2366	36	13	by	by	ADP
admet-2366	36	14	encapsulating	encapsulate	VERB
admet-2366	36	15	them	they	PRON
admet-2366	36	16	in	in	ADP
admet-2366	36	17	lipid	lipid	ADJ
admet-2366	36	18	bilayers	bilayer	NOUN
admet-2366	36	19	,	,	PUNCT
admet-2366	36	20	providing	provide	VERB
admet-2366	36	21	a	a	DET
admet-2366	36	22	suitable	suitable	ADJ
admet-2366	36	23	environment	environment	NOUN
admet-2366	36	24	for	for	SCONJ
admet-2366	36	25	the	the	DET
admet-2366	36	26	drug	drug	NOUN
admet-2366	36	27	to	to	PART
admet-2366	36	28	remain	remain	VERB
admet-2366	36	29	dissolved	dissolved	ADJ
admet-2366	36	30	and	and	CCONJ
admet-2366	36	31	preventing	prevent	VERB
admet-2366	36	32	aggregation	aggregation	NOUN
admet-2366	36	33	and	and	CCONJ
admet-2366	36	34	precipitation	precipitation	NOUN
admet-2366	36	35	.	.	PUNCT
admet-2366	37	1	new	new	ADJ
admet-2366	37	2	drug	drug	NOUN
admet-2366	37	3	delivery	delivery	NOUN
admet-2366	37	4	systems	system	NOUN
admet-2366	37	5	aim	aim	VERB
admet-2366	37	6	to	to	PART
admet-2366	37	7	improve	improve	VERB
admet-2366	37	8	the	the	DET
admet-2366	37	9	curative	curative	ADJ
admet-2366	37	10	value	value	NOUN
admet-2366	37	11	and	and	CCONJ
admet-2366	37	12	safety	safety	NOUN
admet-2366	37	13	profile	profile	NOUN
admet-2366	37	14	of	of	ADP
admet-2366	37	15	available	available	ADJ
admet-2366	37	16	drugs	drug	NOUN
admet-2366	37	17	by	by	ADP
admet-2366	37	18	modifying	modify	VERB
admet-2366	37	19	their	their	PRON
admet-2366	37	20	dose	dose	NOUN
admet-2366	37	21	frequency	frequency	NOUN
admet-2366	37	22	,	,	PUNCT
admet-2366	37	23	bio	bio	ADJ
admet-2366	37	24	-	-	PUNCT
admet-2366	37	25	distribution	distribution	NOUN
admet-2366	37	26	pattern	pattern	NOUN
admet-2366	37	27	,	,	PUNCT
admet-2366	37	28	and	and	CCONJ
admet-2366	37	29	amount	amount	NOUN
admet-2366	37	30	[	[	X
admet-2366	37	31	18,19	18,19	NUM
admet-2366	37	32	]	]	PUNCT
admet-2366	37	33	.	.	PUNCT
admet-2366	38	1	due	due	ADP
admet-2366	38	2	to	to	ADP
admet-2366	38	3	their	their	PRON
admet-2366	38	4	small	small	ADJ
admet-2366	38	5	size	size	NOUN
admet-2366	38	6	and	and	CCONJ
admet-2366	38	7	lipoidal	lipoidal	ADJ
admet-2366	38	8	nature	nature	NOUN
admet-2366	38	9	,	,	PUNCT
admet-2366	38	10	nanoliposomes	nanoliposome	VERB
admet-2366	38	11	improve	improve	VERB
admet-2366	38	12	permeability	permeability	NOUN
admet-2366	38	13	and	and	CCONJ
admet-2366	38	14	accumulate	accumulate	VERB
admet-2366	38	15	in	in	ADP
admet-2366	38	16	tumour	tumour	ADJ
admet-2366	38	17	tissue	tissue	NOUN
admet-2366	39	1	[	[	X
admet-2366	39	2	10,20	10,20	NUM
admet-2366	39	3	]	]	PUNCT
admet-2366	39	4	.	.	PUNCT
admet-2366	40	1	liposomes	liposome	NOUN
admet-2366	40	2	can	can	AUX
admet-2366	40	3	encapsulate	encapsulate	VERB
admet-2366	40	4	both	both	DET
admet-2366	40	5	water	water	NOUN
admet-2366	40	6	-	-	PUNCT
admet-2366	40	7	soluble	soluble	ADJ
admet-2366	40	8	and	and	CCONJ
admet-2366	40	9	water	water	NOUN
admet-2366	40	10	-	-	PUNCT
admet-2366	40	11	insoluble	insoluble	ADJ
admet-2366	40	12	drugs	drug	NOUN
admet-2366	40	13	and	and	CCONJ
admet-2366	40	14	release	release	VERB
admet-2366	40	15	them	they	PRON
admet-2366	40	16	persistently	persistently	ADV
admet-2366	40	17	[	[	X
admet-2366	40	18	13	13	NUM
admet-2366	40	19	]	]	PUNCT
admet-2366	40	20	.	.	PUNCT
admet-2366	41	1	nanoliposomes	nanoliposome	NOUN
admet-2366	41	2	encapsulate	encapsulate	VERB
admet-2366	41	3	anticancer	anticancer	NOUN
admet-2366	41	4	drugs	drug	NOUN
admet-2366	41	5	to	to	PART
admet-2366	41	6	increase	increase	VERB
admet-2366	41	7	systemic	systemic	ADJ
admet-2366	41	8	circulation	circulation	NOUN
admet-2366	41	9	and	and	CCONJ
admet-2366	41	10	reduce	reduce	VERB
admet-2366	41	11	side	side	NOUN
admet-2366	41	12	effects	effect	NOUN
admet-2366	41	13	[	[	X
admet-2366	41	14	14	14	NUM
admet-2366	41	15	]	]	PUNCT
admet-2366	41	16	.	.	PUNCT
admet-2366	42	1	nanoliposomes	nanoliposome	NOUN
admet-2366	42	2	deliver	deliver	VERB
admet-2366	42	3	the	the	DET
admet-2366	42	4	optimum	optimum	ADJ
admet-2366	42	5	drug	drug	NOUN
admet-2366	42	6	to	to	ADP
admet-2366	42	7	the	the	DET
admet-2366	42	8	targeted	target	VERB
admet-2366	42	9	cells	cell	NOUN
admet-2366	42	10	within	within	ADP
admet-2366	42	11	a	a	DET
admet-2366	42	12	sufficient	sufficient	ADJ
admet-2366	42	13	time	time	NOUN
admet-2366	42	14	to	to	PART
admet-2366	42	15	augment	augment	VERB
admet-2366	42	16	the	the	DET
admet-2366	42	17	time	time	NOUN
admet-2366	42	18	of	of	ADP
admet-2366	42	19	curative	curative	ADJ
admet-2366	42	20	action	action	NOUN
admet-2366	42	21	of	of	ADP
admet-2366	42	22	the	the	DET
admet-2366	42	23	exposed	expose	VERB
admet-2366	42	24	drug	drug	NOUN
admet-2366	42	25	[	[	X
admet-2366	42	26	21	21	NUM
admet-2366	42	27	]	]	PUNCT
admet-2366	42	28	.	.	PUNCT
admet-2366	43	1	this	this	DET
admet-2366	43	2	approach	approach	NOUN
admet-2366	43	3	improved	improve	VERB
admet-2366	43	4	medication	medication	NOUN
admet-2366	43	5	stability	stability	NOUN
admet-2366	43	6	and	and	CCONJ
admet-2366	43	7	bioavailability	bioavailability	NOUN
admet-2366	43	8	[	[	X
admet-2366	43	9	22	22	NUM
admet-2366	43	10	]	]	PUNCT
admet-2366	43	11	.	.	PUNCT
admet-2366	44	1	regulatory	regulatory	ADJ
admet-2366	44	2	agencies	agency	NOUN
admet-2366	44	3	have	have	AUX
admet-2366	44	4	recommended	recommend	VERB
admet-2366	44	5	the	the	DET
admet-2366	44	6	use	use	NOUN
admet-2366	44	7	of	of	ADP
admet-2366	44	8	process	process	NOUN
admet-2366	44	9	optimization	optimization	NOUN
admet-2366	44	10	and	and	CCONJ
admet-2366	44	11	quality	quality	NOUN
admet-2366	44	12	by	by	ADP
admet-2366	44	13	design	design	NOUN
admet-2366	44	14	in	in	ADP
admet-2366	44	15	the	the	DET
admet-2366	44	16	design	design	NOUN
admet-2366	44	17	of	of	ADP
admet-2366	44	18	pharmaceutical	pharmaceutical	NOUN
admet-2366	44	19	products	product	NOUN
admet-2366	44	20	.	.	PUNCT
admet-2366	45	1	these	these	DET
admet-2366	45	2	methods	method	NOUN
admet-2366	45	3	will	will	AUX
admet-2366	45	4	help	help	VERB
admet-2366	45	5	create	create	VERB
admet-2366	45	6	nanoparticles	nanoparticle	NOUN
admet-2366	45	7	with	with	ADP
admet-2366	45	8	desired	desire	VERB
admet-2366	45	9	properties	property	NOUN
admet-2366	45	10	and	and	CCONJ
admet-2366	45	11	introduce	introduce	VERB
admet-2366	45	12	a	a	DET
admet-2366	45	13	reproducible	reproducible	ADJ
admet-2366	45	14	,	,	PUNCT
admet-2366	45	15	robust	robust	ADJ
admet-2366	45	16	scale	scale	NOUN
admet-2366	45	17	-	-	PUNCT
admet-2366	45	18	up	up	ADP
admet-2366	45	19	method	method	NOUN
admet-2366	45	20	.	.	PUNCT
admet-2366	46	1	nanoliposomes	nanoliposome	NOUN
admet-2366	46	2	protect	protect	VERB
admet-2366	46	3	the	the	DET
admet-2366	46	4	active	active	ADJ
admet-2366	46	5	therapeutic	therapeutic	ADJ
admet-2366	46	6	molecule	molecule	NOUN
admet-2366	46	7	against	against	ADP
admet-2366	46	8	chemical	chemical	NOUN
admet-2366	46	9	degradation	degradation	NOUN
admet-2366	46	10	and	and	CCONJ
admet-2366	46	11	increase	increase	VERB
admet-2366	46	12	the	the	DET
admet-2366	46	13	rate	rate	NOUN
admet-2366	46	14	of	of	ADP
admet-2366	46	15	component	component	NOUN
admet-2366	46	16	release	release	NOUN
admet-2366	46	17	[	[	X
admet-2366	46	18	23	23	NUM
admet-2366	46	19	]	]	PUNCT
admet-2366	46	20	.	.	PUNCT
admet-2366	47	1	encapsulating	encapsulate	VERB
admet-2366	47	2	gefitinib	gefitinib	NOUN
admet-2366	47	3	in	in	ADP
admet-2366	47	4	liposomes	liposomes	PROPN
admet-2366	47	5	addresses	address	NOUN
admet-2366	47	6	critical	critical	ADJ
admet-2366	47	7	issues	issue	NOUN
admet-2366	47	8	related	relate	VERB
admet-2366	47	9	to	to	ADP
admet-2366	47	10	its	its	PRON
admet-2366	47	11	poor	poor	ADJ
admet-2366	47	12	solubility	solubility	NOUN
admet-2366	47	13	,	,	PUNCT
admet-2366	47	14	bioavailability	bioavailability	NOUN
admet-2366	47	15	,	,	PUNCT
admet-2366	47	16	and	and	CCONJ
admet-2366	47	17	stability	stability	NOUN
admet-2366	47	18	.	.	PUNCT
admet-2366	48	1	this	this	DET
admet-2366	48	2	approach	approach	NOUN
admet-2366	48	3	enhances	enhance	VERB
admet-2366	48	4	the	the	DET
admet-2366	48	5	therapeutic	therapeutic	ADJ
admet-2366	48	6	efficacy	efficacy	NOUN
admet-2366	48	7	of	of	ADP
admet-2366	48	8	gefitinib	gefitinib	NOUN
admet-2366	48	9	,	,	PUNCT
admet-2366	48	10	reduces	reduce	VERB
admet-2366	48	11	side	side	NOUN
admet-2366	48	12	effects	effect	NOUN
admet-2366	48	13	,	,	PUNCT
admet-2366	48	14	enables	enable	VERB
admet-2366	48	15	targeted	target	VERB
admet-2366	48	16	and	and	CCONJ
admet-2366	48	17	controlled	control	VERB
admet-2366	48	18	drug	drug	NOUN
admet-2366	48	19	delivery	delivery	NOUN
admet-2366	48	20	,	,	PUNCT
admet-2366	48	21	and	and	CCONJ
admet-2366	48	22	potentially	potentially	ADV
admet-2366	48	23	overcomes	overcome	VERB
admet-2366	48	24	drug	drug	NOUN
admet-2366	48	25	resistance	resistance	NOUN
admet-2366	48	26	,	,	PUNCT
admet-2366	48	27	making	make	VERB
admet-2366	48	28	it	it	PRON
admet-2366	48	29	a	a	DET
admet-2366	48	30	valuable	valuable	ADJ
admet-2366	48	31	strategy	strategy	NOUN
admet-2366	48	32	in	in	ADP
admet-2366	48	33	cancer	cancer	NOUN
admet-2366	48	34	treatment	treatment	NOUN
admet-2366	48	35	.	.	PUNCT
admet-2366	49	1	the	the	DET
admet-2366	49	2	formulation	formulation	NOUN
admet-2366	49	3	protocol	protocol	NOUN
admet-2366	49	4	is	be	AUX
admet-2366	49	5	optimized	optimize	VERB
admet-2366	49	6	by	by	ADP
admet-2366	49	7	using	use	VERB
admet-2366	49	8	different	different	ADJ
admet-2366	49	9	designs	design	NOUN
admet-2366	49	10	such	such	ADJ
admet-2366	49	11	as	as	ADP
admet-2366	49	12	box	box	NOUN
admet-2366	49	13	-	-	PUNCT
admet-2366	49	14	behnken	behnken	VERB
admet-2366	49	15	design	design	NOUN
admet-2366	49	16	(	(	PUNCT
admet-2366	49	17	bbd	bbd	PROPN
admet-2366	49	18	)	)	PUNCT
admet-2366	49	19	,	,	PUNCT
admet-2366	49	20	and	and	CCONJ
admet-2366	49	21	d	d	X
admet-2366	49	22	-	-	ADJ
admet-2366	49	23	optimal	optimal	ADJ
admet-2366	49	24	design	design	NOUN
admet-2366	49	25	of	of	ADP
admet-2366	49	26	response	response	NOUN
admet-2366	49	27	surface	surface	NOUN
admet-2366	49	28	methodology	methodology	NOUN
admet-2366	49	29	(	(	PUNCT
admet-2366	49	30	rsm	rsm	NOUN
admet-2366	49	31	)	)	PUNCT
admet-2366	49	32	.	.	PUNCT
admet-2366	50	1	in	in	ADP
admet-2366	50	2	the	the	DET
admet-2366	50	3	present	present	ADJ
admet-2366	50	4	study	study	NOUN
admet-2366	50	5	,	,	PUNCT
admet-2366	50	6	the	the	DET
admet-2366	50	7	bbd	bbd	PROPN
admet-2366	50	8	was	be	AUX
admet-2366	50	9	used	use	VERB
admet-2366	50	10	to	to	PART
admet-2366	50	11	optimize	optimize	VERB
admet-2366	50	12	the	the	DET
admet-2366	50	13	process	process	NOUN
admet-2366	50	14	,	,	PUNCT
admet-2366	50	15	as	as	SCONJ
admet-2366	50	16	it	it	PRON
admet-2366	50	17	produced	produce	VERB
admet-2366	50	18	fewer	few	ADJ
admet-2366	50	19	runs	run	NOUN
admet-2366	50	20	than	than	ADP
admet-2366	50	21	the	the	DET
admet-2366	50	22	central	central	ADJ
admet-2366	50	23	composite	composite	ADJ
admet-2366	50	24	design	design	NOUN
admet-2366	50	25	with	with	ADP
admet-2366	50	26	three	three	NUM
admet-2366	50	27	variables	variable	NOUN
admet-2366	51	1	[	[	X
admet-2366	51	2	24	24	NUM
admet-2366	51	3	-	-	SYM
admet-2366	51	4	26	26	NUM
admet-2366	51	5	]	]	PUNCT
admet-2366	51	6	.	.	PUNCT
admet-2366	52	1	the	the	DET
admet-2366	52	2	admet	admet	PROPN
admet-2366	52	3	&	&	CCONJ
admet-2366	52	4	dmpk	dmpk	PROPN
admet-2366	52	5	12(4	12(4	PROPN
admet-2366	52	6	)	)	PUNCT
admet-2366	52	7	(	(	PUNCT
admet-2366	52	8	2024	2024	NUM
admet-2366	52	9	)	)	PUNCT
admet-2366	52	10	657	657	NUM
admet-2366	52	11	-	-	SYM
admet-2366	52	12	677	677	NUM
admet-2366	52	13	optimizing	optimizing	NOUN
admet-2366	52	14	gefitinib	gefitinib	NOUN
admet-2366	52	15	nanoliposomes	nanoliposomes	ADV
admet-2366	52	16	doi	doi	ADV
admet-2366	52	17	:	:	PUNCT
admet-2366	52	18	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PROPN
admet-2366	52	19	659	659	NUM
admet-2366	52	20	bbd	bbd	PROPN
admet-2366	52	21	has	have	VERB
admet-2366	52	22	many	many	ADJ
admet-2366	52	23	advantages	advantage	NOUN
admet-2366	52	24	over	over	ADP
admet-2366	52	25	other	other	ADJ
admet-2366	52	26	experimental	experimental	ADJ
admet-2366	52	27	designs	design	NOUN
admet-2366	52	28	.	.	PUNCT
admet-2366	53	1	in	in	ADP
admet-2366	53	2	this	this	PRON
admet-2366	53	3	,	,	PUNCT
admet-2366	53	4	a	a	DET
admet-2366	53	5	minimum	minimum	NOUN
admet-2366	53	6	of	of	ADP
admet-2366	53	7	three	three	NUM
admet-2366	53	8	levels	level	NOUN
admet-2366	53	9	of	of	ADP
admet-2366	53	10	independent	independent	ADJ
admet-2366	53	11	variables	variable	NOUN
admet-2366	53	12	must	must	AUX
admet-2366	53	13	be	be	AUX
admet-2366	53	14	required	require	VERB
admet-2366	53	15	to	to	PART
admet-2366	53	16	run	run	VERB
admet-2366	53	17	,	,	PUNCT
admet-2366	53	18	and	and	CCONJ
admet-2366	53	19	the	the	DET
admet-2366	53	20	divergence	divergence	NOUN
admet-2366	53	21	from	from	ADP
admet-2366	53	22	the	the	DET
admet-2366	53	23	predictable	predictable	ADJ
admet-2366	53	24	outcomes	outcome	NOUN
admet-2366	53	25	at	at	ADP
admet-2366	53	26	any	any	DET
admet-2366	53	27	point	point	NOUN
admet-2366	53	28	is	be	AUX
admet-2366	53	29	identified	identify	VERB
admet-2366	53	30	exclusively	exclusively	ADV
admet-2366	53	31	by	by	ADP
admet-2366	53	32	its	its	PRON
admet-2366	53	33	expanse	expanse	NOUN
admet-2366	53	34	from	from	ADP
admet-2366	53	35	the	the	DET
admet-2366	53	36	design	design	NOUN
admet-2366	53	37	centre	centre	NOUN
admet-2366	53	38	point	point	NOUN
admet-2366	53	39	[	[	X
admet-2366	53	40	27	27	NUM
admet-2366	53	41	]	]	PUNCT
admet-2366	53	42	.	.	PUNCT
admet-2366	54	1	thus	thus	ADV
admet-2366	54	2	,	,	PUNCT
admet-2366	54	3	it	it	PRON
admet-2366	54	4	reduces	reduce	VERB
admet-2366	54	5	the	the	DET
admet-2366	54	6	cost	cost	NOUN
admet-2366	54	7	associated	associate	VERB
admet-2366	54	8	with	with	ADP
admet-2366	54	9	the	the	DET
admet-2366	54	10	expensive	expensive	ADJ
admet-2366	54	11	critical	critical	ADJ
admet-2366	54	12	methods	method	NOUN
admet-2366	54	13	by	by	ADP
admet-2366	54	14	reducing	reduce	VERB
admet-2366	54	15	their	their	PRON
admet-2366	54	16	computational	computational	ADJ
admet-2366	54	17	noise	noise	NOUN
admet-2366	54	18	.	.	PUNCT
admet-2366	55	1	the	the	DET
admet-2366	55	2	bbd	bbd	PROPN
admet-2366	55	3	used	use	VERB
admet-2366	55	4	the	the	DET
admet-2366	55	5	response	response	NOUN
admet-2366	55	6	surface	surface	NOUN
admet-2366	55	7	methodology	methodology	NOUN
admet-2366	55	8	to	to	PART
admet-2366	55	9	select	select	VERB
admet-2366	55	10	the	the	DET
admet-2366	55	11	optimal	optimal	ADJ
admet-2366	55	12	responses	response	NOUN
admet-2366	55	13	for	for	ADP
admet-2366	55	14	a	a	DET
admet-2366	55	15	precise	precise	ADJ
admet-2366	55	16	reaction	reaction	NOUN
admet-2366	55	17	[	[	X
admet-2366	55	18	28	28	NUM
admet-2366	55	19	]	]	PUNCT
admet-2366	55	20	.	.	PUNCT
admet-2366	56	1	chitosan	chitosan	PROPN
admet-2366	56	2	is	be	AUX
admet-2366	56	3	an	an	DET
admet-2366	56	4	n	n	ADV
admet-2366	56	5	-	-	PUNCT
admet-2366	56	6	deacetylated	deacetylate	VERB
admet-2366	56	7	derivative	derivative	NOUN
admet-2366	56	8	of	of	ADP
admet-2366	56	9	chitin	chitin	NOUN
admet-2366	56	10	and	and	CCONJ
admet-2366	56	11	contains	contain	VERB
admet-2366	56	12	chiefly	chiefly	ADV
admet-2366	56	13	glucosamine	glucosamine	NOUN
admet-2366	56	14	units	unit	NOUN
admet-2366	56	15	.	.	PUNCT
admet-2366	57	1	it	it	PRON
admet-2366	57	2	acts	act	VERB
admet-2366	57	3	like	like	ADP
admet-2366	57	4	a	a	DET
admet-2366	57	5	polycationic	polycationic	ADJ
admet-2366	57	6	polymer	polymer	NOUN
admet-2366	57	7	due	due	ADP
admet-2366	57	8	to	to	ADP
admet-2366	57	9	the	the	DET
admet-2366	57	10	presence	presence	NOUN
admet-2366	57	11	of	of	ADP
admet-2366	57	12	amino	amino	NOUN
admet-2366	57	13	groups	group	NOUN
admet-2366	57	14	.	.	PUNCT
admet-2366	58	1	it	it	PRON
admet-2366	58	2	has	have	VERB
admet-2366	58	3	anti	anti	ADJ
admet-2366	58	4	-	-	ADJ
admet-2366	58	5	inflammatory	inflammatory	ADJ
admet-2366	58	6	and	and	CCONJ
admet-2366	58	7	antioxidant	antioxidant	ADJ
admet-2366	58	8	properties	property	NOUN
admet-2366	58	9	[	[	X
admet-2366	58	10	29,30	29,30	NUM
admet-2366	58	11	]	]	PUNCT
admet-2366	58	12	.	.	PUNCT
admet-2366	59	1	the	the	DET
admet-2366	59	2	destructive	destructive	ADJ
admet-2366	59	3	effects	effect	NOUN
admet-2366	59	4	of	of	ADP
admet-2366	59	5	gastrointestinal	gastrointestinal	ADJ
admet-2366	59	6	tract	tract	NOUN
admet-2366	59	7	ph	ph	VERB
admet-2366	59	8	,	,	PUNCT
admet-2366	59	9	bile	bile	NOUN
admet-2366	59	10	salts	salt	NOUN
admet-2366	59	11	,	,	PUNCT
admet-2366	59	12	and	and	CCONJ
admet-2366	59	13	pancreatic	pancreatic	ADJ
admet-2366	59	14	lipase	lipase	NOUN
admet-2366	59	15	offered	offer	VERB
admet-2366	59	16	a	a	DET
admet-2366	59	17	great	great	ADJ
admet-2366	59	18	challenge	challenge	NOUN
admet-2366	59	19	for	for	ADP
admet-2366	59	20	liposomal	liposomal	ADJ
admet-2366	59	21	delivery	delivery	NOUN
admet-2366	59	22	systems	system	NOUN
admet-2366	59	23	.	.	PUNCT
admet-2366	60	1	chitosan	chitosan	ADJ
admet-2366	60	2	or	or	CCONJ
admet-2366	60	3	related	relate	VERB
admet-2366	60	4	polymers	polymer	NOUN
admet-2366	60	5	are	be	AUX
admet-2366	60	6	used	use	VERB
admet-2366	60	7	as	as	ADP
admet-2366	60	8	coating	coat	VERB
admet-2366	60	9	materials	material	NOUN
admet-2366	60	10	to	to	PART
admet-2366	60	11	improve	improve	VERB
admet-2366	60	12	the	the	DET
admet-2366	60	13	stability	stability	NOUN
admet-2366	60	14	of	of	ADP
admet-2366	60	15	nano	nano	NOUN
admet-2366	60	16	-	-	PUNCT
admet-2366	60	17	formulations	formulation	NOUN
admet-2366	60	18	and	and	CCONJ
admet-2366	60	19	achieve	achieve	VERB
admet-2366	60	20	targeted	target	VERB
admet-2366	60	21	payload	payload	NOUN
admet-2366	60	22	delivery	delivery	NOUN
admet-2366	60	23	[	[	X
admet-2366	60	24	31	31	NUM
admet-2366	60	25	]	]	PUNCT
admet-2366	60	26	.	.	PUNCT
admet-2366	61	1	literature	literature	NOUN
admet-2366	61	2	demonstrated	demonstrate	VERB
admet-2366	61	3	that	that	SCONJ
admet-2366	61	4	an	an	DET
admet-2366	61	5	amendment	amendment	NOUN
admet-2366	61	6	in	in	ADP
admet-2366	61	7	the	the	DET
admet-2366	61	8	ratio	ratio	NOUN
admet-2366	61	9	of	of	ADP
admet-2366	61	10	the	the	DET
admet-2366	61	11	lipid	lipid	NOUN
admet-2366	61	12	-	-	PUNCT
admet-2366	61	13	based	base	VERB
admet-2366	61	14	and	and	CCONJ
admet-2366	61	15	polymer	polymer	NOUN
admet-2366	61	16	-	-	PUNCT
admet-2366	61	17	based	base	VERB
admet-2366	61	18	systems	system	NOUN
admet-2366	61	19	led	lead	VERB
admet-2366	61	20	to	to	ADP
admet-2366	61	21	the	the	DET
admet-2366	61	22	development	development	NOUN
admet-2366	61	23	of	of	ADP
admet-2366	61	24	a	a	DET
admet-2366	61	25	new	new	ADJ
admet-2366	61	26	system	system	NOUN
admet-2366	61	27	[	[	X
admet-2366	61	28	32	32	NUM
admet-2366	61	29	]	]	PUNCT
admet-2366	61	30	.	.	PUNCT
admet-2366	62	1	positively	positively	ADV
admet-2366	62	2	charged	charge	VERB
admet-2366	62	3	chitosan	chitosan	NOUN
admet-2366	62	4	forms	form	NOUN
admet-2366	62	5	an	an	DET
admet-2366	62	6	ionic	ionic	ADJ
admet-2366	62	7	bond	bond	NOUN
admet-2366	62	8	with	with	ADP
admet-2366	62	9	the	the	DET
admet-2366	62	10	negatively	negatively	ADV
admet-2366	62	11	charged	charge	VERB
admet-2366	62	12	nanoliposomes	nanoliposome	NOUN
admet-2366	62	13	to	to	PART
admet-2366	62	14	produce	produce	VERB
admet-2366	62	15	a	a	DET
admet-2366	62	16	uniform	uniform	ADJ
admet-2366	62	17	coating	coating	NOUN
admet-2366	62	18	on	on	ADP
admet-2366	62	19	the	the	DET
admet-2366	62	20	nanoliposome	nanoliposome	NOUN
admet-2366	62	21	surface	surface	NOUN
admet-2366	63	1	[	[	X
admet-2366	63	2	33,34	33,34	NOUN
admet-2366	63	3	]	]	PUNCT
admet-2366	63	4	.	.	PUNCT
admet-2366	64	1	this	this	DET
admet-2366	64	2	coating	coating	NOUN
admet-2366	64	3	rendered	render	VERB
admet-2366	64	4	them	they	PRON
admet-2366	64	5	mucoadhesive	mucoadhesive	ADJ
admet-2366	64	6	and	and	CCONJ
admet-2366	64	7	augmented	augment	VERB
admet-2366	64	8	their	their	PRON
admet-2366	64	9	stability	stability	NOUN
admet-2366	64	10	profile	profile	NOUN
admet-2366	64	11	[	[	X
admet-2366	64	12	30,34	30,34	NOUN
admet-2366	64	13	]	]	PUNCT
admet-2366	64	14	.	.	PUNCT
admet-2366	65	1	coating	coat	VERB
admet-2366	65	2	with	with	ADP
admet-2366	65	3	polymers	polymer	NOUN
admet-2366	65	4	of	of	ADP
admet-2366	65	5	desired	desire	VERB
admet-2366	65	6	characteristics	characteristic	NOUN
admet-2366	65	7	is	be	AUX
admet-2366	65	8	a	a	DET
admet-2366	65	9	confirmed	confirm	VERB
admet-2366	65	10	method	method	NOUN
admet-2366	65	11	to	to	PART
admet-2366	65	12	modify	modify	VERB
admet-2366	65	13	the	the	DET
admet-2366	65	14	surface	surface	NOUN
admet-2366	65	15	properties	property	NOUN
admet-2366	65	16	of	of	ADP
admet-2366	65	17	nanocarriers	nanocarrier	NOUN
admet-2366	65	18	.	.	PUNCT
admet-2366	66	1	to	to	PART
admet-2366	66	2	coat	coat	VERB
admet-2366	66	3	,	,	PUNCT
admet-2366	66	4	nanoliposomes	nanoliposome	NOUN
admet-2366	66	5	are	be	AUX
admet-2366	66	6	simply	simply	ADV
admet-2366	66	7	mixed	mix	VERB
admet-2366	66	8	with	with	ADP
admet-2366	66	9	a	a	DET
admet-2366	66	10	polymer	polymer	NOUN
admet-2366	66	11	solution	solution	NOUN
admet-2366	66	12	.	.	PUNCT
admet-2366	67	1	this	this	PRON
admet-2366	67	2	improves	improve	VERB
admet-2366	67	3	the	the	DET
admet-2366	67	4	mutual	mutual	ADJ
admet-2366	67	5	repulsion	repulsion	NOUN
admet-2366	67	6	among	among	ADP
admet-2366	67	7	the	the	DET
admet-2366	67	8	adjacent	adjacent	ADJ
admet-2366	67	9	bilayers	bilayer	NOUN
admet-2366	67	10	during	during	ADP
admet-2366	67	11	storage	storage	NOUN
admet-2366	67	12	and	and	CCONJ
admet-2366	67	13	thus	thus	ADV
admet-2366	67	14	improves	improve	VERB
admet-2366	67	15	the	the	DET
admet-2366	67	16	stability	stability	NOUN
admet-2366	67	17	of	of	ADP
admet-2366	67	18	nanoliposomes	nanoliposome	NOUN
admet-2366	67	19	.	.	PUNCT
admet-2366	68	1	different	different	ADJ
admet-2366	68	2	synthetic	synthetic	ADJ
admet-2366	68	3	and	and	CCONJ
admet-2366	68	4	natural	natural	ADJ
admet-2366	68	5	polymers	polymer	NOUN
admet-2366	68	6	have	have	AUX
admet-2366	68	7	been	be	AUX
admet-2366	68	8	used	use	VERB
admet-2366	68	9	to	to	PART
admet-2366	68	10	modify	modify	VERB
admet-2366	68	11	the	the	DET
admet-2366	68	12	exterior	exterior	ADJ
admet-2366	68	13	character	character	NOUN
admet-2366	68	14	of	of	ADP
admet-2366	68	15	nanoliposomes	nanoliposome	NOUN
admet-2366	68	16	.	.	PUNCT
admet-2366	69	1	we	we	PRON
admet-2366	69	2	find	find	VERB
admet-2366	69	3	chitosan	chitosan	NOUN
admet-2366	69	4	to	to	PART
admet-2366	69	5	be	be	AUX
admet-2366	69	6	the	the	DET
admet-2366	69	7	most	most	ADV
admet-2366	69	8	suitable	suitable	ADJ
admet-2366	69	9	in	in	ADP
admet-2366	69	10	this	this	DET
admet-2366	69	11	context	context	NOUN
admet-2366	69	12	because	because	SCONJ
admet-2366	69	13	of	of	ADP
admet-2366	69	14	its	its	PRON
admet-2366	69	15	positive	positive	ADJ
admet-2366	69	16	charge	charge	NOUN
admet-2366	69	17	,	,	PUNCT
admet-2366	69	18	and	and	CCONJ
admet-2366	69	19	we	we	PRON
admet-2366	69	20	assume	assume	VERB
admet-2366	69	21	it	it	PRON
admet-2366	69	22	has	have	VERB
admet-2366	69	23	an	an	DET
admet-2366	69	24	optimistic	optimistic	ADJ
admet-2366	69	25	future	future	NOUN
admet-2366	69	26	in	in	ADP
admet-2366	69	27	the	the	DET
admet-2366	69	28	pharmaceutical	pharmaceutical	ADJ
admet-2366	69	29	field	field	NOUN
admet-2366	69	30	.	.	PUNCT
admet-2366	70	1	in	in	ADP
admet-2366	70	2	the	the	DET
admet-2366	70	3	present	present	ADJ
admet-2366	70	4	study	study	NOUN
admet-2366	70	5	,	,	PUNCT
admet-2366	70	6	gefitinib	gefitinib	NOUN
admet-2366	70	7	-	-	PUNCT
admet-2366	70	8	loaded	load	VERB
admet-2366	70	9	nanoliposomes	nanoliposome	NOUN
admet-2366	70	10	were	be	AUX
admet-2366	70	11	prepared	prepare	VERB
admet-2366	70	12	by	by	ADP
admet-2366	70	13	the	the	DET
admet-2366	70	14	reverse	reverse	ADJ
admet-2366	70	15	phase	phase	NOUN
admet-2366	70	16	evaporation	evaporation	NOUN
admet-2366	70	17	method	method	NOUN
admet-2366	70	18	and	and	CCONJ
admet-2366	70	19	optimized	optimize	VERB
admet-2366	70	20	using	use	VERB
admet-2366	70	21	bbd	bbd	PROPN
admet-2366	70	22	.	.	PUNCT
admet-2366	71	1	the	the	DET
admet-2366	71	2	potential	potential	ADJ
admet-2366	71	3	rationale	rationale	NOUN
admet-2366	71	4	for	for	ADP
admet-2366	71	5	conducting	conduct	VERB
admet-2366	71	6	this	this	DET
admet-2366	71	7	study	study	NOUN
admet-2366	71	8	was	be	AUX
admet-2366	71	9	to	to	PART
admet-2366	71	10	scrutinize	scrutinize	VERB
admet-2366	71	11	the	the	DET
admet-2366	71	12	consequences	consequence	NOUN
admet-2366	71	13	of	of	ADP
admet-2366	71	14	sonication	sonication	NOUN
admet-2366	71	15	time	time	NOUN
admet-2366	71	16	(	(	PUNCT
admet-2366	71	17	x1	x1	PROPN
admet-2366	71	18	)	)	PUNCT
admet-2366	71	19	,	,	PUNCT
admet-2366	71	20	the	the	DET
admet-2366	71	21	ratio	ratio	NOUN
admet-2366	71	22	of	of	ADP
admet-2366	71	23	tween	tween	NOUN
admet-2366	71	24	80	80	NUM
admet-2366	71	25	to	to	ADP
admet-2366	71	26	soya	soya	PROPN
admet-2366	71	27	phosphatidylcholine	phosphatidylcholine	NOUN
admet-2366	71	28	(	(	PUNCT
admet-2366	71	29	x2	x2	PROPN
admet-2366	71	30	)	)	PUNCT
admet-2366	71	31	,	,	PUNCT
admet-2366	71	32	and	and	CCONJ
admet-2366	71	33	the	the	DET
admet-2366	71	34	ratio	ratio	NOUN
admet-2366	71	35	of	of	ADP
admet-2366	71	36	cholesterol	cholesterol	NOUN
admet-2366	71	37	to	to	ADP
admet-2366	71	38	soya	soya	NOUN
admet-2366	71	39	phosphatidylcholine	phosphatidylcholine	NOUN
admet-2366	71	40	(	(	PUNCT
admet-2366	71	41	x3	x3	ADJ
admet-2366	71	42	)	)	PUNCT
admet-2366	71	43	on	on	ADP
admet-2366	71	44	particle	particle	NOUN
admet-2366	71	45	size	size	NOUN
admet-2366	71	46	and	and	CCONJ
admet-2366	71	47	entrapment	entrapment	ADJ
admet-2366	71	48	efficiency	efficiency	NOUN
admet-2366	71	49	of	of	ADP
admet-2366	71	50	gefitinib	gefitinib	NOUN
admet-2366	71	51	-	-	PUNCT
admet-2366	71	52	loaded	load	VERB
admet-2366	71	53	nanoliposomes	nanoliposome	NOUN
admet-2366	71	54	.	.	PUNCT
admet-2366	72	1	the	the	DET
admet-2366	72	2	optimum	optimum	ADJ
admet-2366	72	3	batches	batch	NOUN
admet-2366	72	4	were	be	AUX
admet-2366	72	5	then	then	ADV
admet-2366	72	6	encrusted	encrust	VERB
admet-2366	72	7	by	by	ADP
admet-2366	72	8	using	use	VERB
admet-2366	72	9	varying	vary	VERB
admet-2366	72	10	concentrations	concentration	NOUN
admet-2366	72	11	of	of	ADP
admet-2366	72	12	chitosan	chitosan	ADJ
admet-2366	72	13	solutions	solution	NOUN
admet-2366	72	14	.	.	PUNCT
admet-2366	73	1	the	the	DET
admet-2366	73	2	optimum	optimum	ADJ
admet-2366	73	3	concentration	concentration	NOUN
admet-2366	73	4	for	for	ADP
admet-2366	73	5	the	the	DET
admet-2366	73	6	coating	coating	NOUN
admet-2366	73	7	of	of	ADP
admet-2366	73	8	nanoliposomes	nanoliposome	NOUN
admet-2366	73	9	was	be	AUX
admet-2366	73	10	found	find	VERB
admet-2366	73	11	to	to	PART
admet-2366	73	12	be	be	AUX
admet-2366	73	13	0.01	0.01	NUM
admet-2366	73	14	%	%	NOUN
admet-2366	73	15	as	as	SCONJ
admet-2366	73	16	reported	report	VERB
admet-2366	73	17	in	in	ADP
admet-2366	73	18	our	our	PRON
admet-2366	73	19	previous	previous	ADJ
admet-2366	73	20	communication	communication	NOUN
admet-2366	73	21	[	[	X
admet-2366	73	22	30	30	NUM
admet-2366	73	23	]	]	PUNCT
admet-2366	73	24	.	.	PUNCT
admet-2366	74	1	different	different	ADJ
admet-2366	74	2	techniques	technique	NOUN
admet-2366	74	3	like	like	ADP
admet-2366	74	4	ftir	ftir	PROPN
admet-2366	74	5	studies	studies	PROPN
admet-2366	74	6	,	,	PUNCT
admet-2366	74	7	dsc	dsc	NOUN
admet-2366	74	8	analysis	analysis	NOUN
admet-2366	74	9	,	,	PUNCT
admet-2366	74	10	zeta	zeta	NOUN
admet-2366	74	11	potential	potential	ADJ
admet-2366	74	12	studies	study	NOUN
admet-2366	74	13	,	,	PUNCT
admet-2366	74	14	transmission	transmission	NOUN
admet-2366	74	15	electron	electron	NOUN
admet-2366	74	16	microscopy	microscopy	NOUN
admet-2366	74	17	,	,	PUNCT
admet-2366	74	18	and	and	CCONJ
admet-2366	74	19	particle	particle	NOUN
admet-2366	74	20	size	size	NOUN
admet-2366	74	21	analysis	analysis	NOUN
admet-2366	74	22	were	be	AUX
admet-2366	74	23	used	use	VERB
admet-2366	74	24	to	to	PART
admet-2366	74	25	confirm	confirm	VERB
admet-2366	74	26	the	the	DET
admet-2366	74	27	presence	presence	NOUN
admet-2366	74	28	of	of	ADP
admet-2366	74	29	chitosan	chitosan	NOUN
admet-2366	74	30	coating	coating	NOUN
admet-2366	74	31	on	on	ADP
admet-2366	74	32	nanoliposomes	nanoliposome	NOUN
admet-2366	74	33	.	.	PUNCT
admet-2366	75	1	further	further	ADJ
admet-2366	75	2	optimization	optimization	NOUN
admet-2366	75	3	of	of	ADP
admet-2366	75	4	nanoliposomes	nanoliposome	NOUN
admet-2366	75	5	was	be	AUX
admet-2366	75	6	done	do	VERB
admet-2366	75	7	for	for	ADP
admet-2366	75	8	their	their	PRON
admet-2366	75	9	systemic	systemic	ADJ
admet-2366	75	10	therapeutic	therapeutic	ADJ
admet-2366	75	11	purposes	purpose	NOUN
admet-2366	75	12	by	by	ADP
admet-2366	75	13	characterizing	characterize	VERB
admet-2366	75	14	the	the	DET
admet-2366	75	15	uncoated	uncoated	ADJ
admet-2366	75	16	and	and	CCONJ
admet-2366	75	17	surface	surface	NOUN
admet-2366	75	18	-	-	PUNCT
admet-2366	75	19	adorned	adorn	VERB
admet-2366	75	20	nanoliposomes	nanoliposome	NOUN
admet-2366	75	21	.	.	PUNCT
admet-2366	76	1	the	the	DET
admet-2366	76	2	mtt	mtt	NOUN
admet-2366	76	3	assay	assay	VERB
admet-2366	76	4	was	be	AUX
admet-2366	76	5	used	use	VERB
admet-2366	76	6	to	to	PART
admet-2366	76	7	test	test	VERB
admet-2366	76	8	the	the	DET
admet-2366	76	9	cytotoxicity	cytotoxicity	NOUN
admet-2366	76	10	of	of	ADP
admet-2366	76	11	gefitinib	gefitinib	NOUN
admet-2366	76	12	-	-	PUNCT
admet-2366	76	13	loaded	load	VERB
admet-2366	76	14	nanoliposomes	nanoliposome	NOUN
admet-2366	76	15	and	and	CCONJ
admet-2366	76	16	chitosan	chitosan	NOUN
admet-2366	76	17	-	-	PUNCT
admet-2366	76	18	coated	coat	VERB
admet-2366	76	19	gefitinib	gefitinib	NOUN
admet-2366	76	20	nanoliposomes	nanoliposome	VERB
admet-2366	76	21	on	on	ADP
admet-2366	76	22	a	a	DET
admet-2366	76	23	human	human	ADJ
admet-2366	76	24	non	non	ADJ
admet-2366	76	25	-	-	ADJ
admet-2366	76	26	small	small	ADJ
admet-2366	76	27	cell	cell	NOUN
admet-2366	76	28	lung	lung	NOUN
admet-2366	76	29	carcinoma	carcinoma	NOUN
admet-2366	76	30	cell	cell	NOUN
admet-2366	76	31	line	line	NOUN
admet-2366	76	32	(	(	PUNCT
admet-2366	76	33	h1299	h1299	NOUN
admet-2366	76	34	)	)	PUNCT
admet-2366	76	35	and	and	CCONJ
admet-2366	76	36	human	human	ADJ
admet-2366	76	37	adenocarcinomic	adenocarcinomic	ADJ
admet-2366	76	38	alveolar	alveolar	ADJ
admet-2366	76	39	basal	basal	ADJ
admet-2366	76	40	epithelial	epithelial	ADJ
admet-2366	76	41	cells	cell	NOUN
admet-2366	76	42	(	(	PUNCT
admet-2366	76	43	a549	a549	PROPN
admet-2366	76	44	)	)	PUNCT
admet-2366	76	45	.	.	PUNCT
admet-2366	77	1	ich	ich	NOUN
admet-2366	77	2	guidelines	guideline	NOUN
admet-2366	77	3	were	be	AUX
admet-2366	77	4	followed	follow	VERB
admet-2366	77	5	to	to	PART
admet-2366	77	6	perform	perform	VERB
admet-2366	77	7	the	the	DET
admet-2366	77	8	stability	stability	NOUN
admet-2366	77	9	studies	study	NOUN
admet-2366	77	10	on	on	ADP
admet-2366	77	11	optimized	optimize	VERB
admet-2366	77	12	batches	batch	NOUN
admet-2366	77	13	.	.	PUNCT
admet-2366	78	1	experimental	experimental	ADJ
admet-2366	78	2	materials	material	NOUN
admet-2366	78	3	mac	mac	PROPN
admet-2366	78	4	chem	chem	NOUN
admet-2366	78	5	products	product	NOUN
admet-2366	78	6	india	india	PROPN
admet-2366	78	7	pvt	pvt	PROPN
admet-2366	78	8	.	.	PROPN
admet-2366	78	9	ltd	ltd	PROPN
admet-2366	78	10	.	.	PROPN
admet-2366	78	11	,	,	PUNCT
admet-2366	78	12	mumbai	mumbai	PROPN
admet-2366	78	13	,	,	PUNCT
admet-2366	78	14	india	india	PROPN
admet-2366	78	15	,	,	PUNCT
admet-2366	78	16	gifted	gifted	ADJ
admet-2366	78	17	gefitinib	gefitinib	NOUN
admet-2366	78	18	sample	sample	NOUN
admet-2366	78	19	.	.	PUNCT
admet-2366	79	1	dimethyl	dimethyl	NOUN
admet-2366	79	2	sulfoxide	sulfoxide	NOUN
admet-2366	79	3	,	,	PUNCT
admet-2366	79	4	tween	tween	NOUN
admet-2366	79	5	80	80	NUM
admet-2366	79	6	,	,	PUNCT
admet-2366	79	7	potassium	potassium	NOUN
admet-2366	79	8	dihydrogen	dihydrogen	NOUN
admet-2366	79	9	orthophosphate	orthophosphate	NOUN
admet-2366	79	10	,	,	PUNCT
admet-2366	79	11	and	and	CCONJ
admet-2366	79	12	diethyl	diethyl	NOUN
admet-2366	79	13	ether	ether	NOUN
admet-2366	79	14	were	be	AUX
admet-2366	79	15	obtained	obtain	VERB
admet-2366	79	16	from	from	ADP
admet-2366	79	17	loba	loba	PROPN
admet-2366	79	18	chemie	chemie	PROPN
admet-2366	79	19	,	,	PUNCT
admet-2366	79	20	india	india	PROPN
admet-2366	79	21	.	.	PUNCT
admet-2366	80	1	cholesterol	cholesterol	PROPN
admet-2366	80	2	was	be	AUX
admet-2366	80	3	purchased	purchase	VERB
admet-2366	80	4	from	from	ADP
admet-2366	80	5	sigma	sigma	PROPN
admet-2366	80	6	aldrich	aldrich	PROPN
admet-2366	80	7	,	,	PUNCT
admet-2366	80	8	mo	mo	PROPN
admet-2366	80	9	,	,	PUNCT
admet-2366	80	10	usa	usa	PROPN
admet-2366	80	11	.	.	PROPN
admet-2366	80	12	soya	soya	PROPN
admet-2366	80	13	phosphatidylcholine	phosphatidylcholine	PROPN
admet-2366	80	14	was	be	AUX
admet-2366	80	15	purchased	purchase	VERB
admet-2366	80	16	from	from	ADP
admet-2366	80	17	central	central	ADJ
admet-2366	80	18	drug	drug	NOUN
admet-2366	80	19	house	house	NOUN
admet-2366	80	20	(	(	PUNCT
admet-2366	80	21	p	p	PROPN
admet-2366	80	22	)	)	PUNCT
admet-2366	80	23	ltd	ltd	PROPN
admet-2366	80	24	.	.	PROPN
admet-2366	80	25	,	,	PUNCT
admet-2366	80	26	new	new	PROPN
admet-2366	80	27	delhi	delhi	PROPN
admet-2366	80	28	,	,	PUNCT
admet-2366	80	29	india	india	PROPN
admet-2366	80	30	.	.	PUNCT
admet-2366	81	1	chitosan	chitosan	PROPN
admet-2366	81	2	was	be	AUX
admet-2366	81	3	purchased	purchase	VERB
admet-2366	81	4	from	from	ADP
admet-2366	81	5	fluka	fluka	PROPN
admet-2366	81	6	chemie	chemie	PROPN
admet-2366	81	7	,	,	PUNCT
admet-2366	81	8	germany	germany	PROPN
admet-2366	81	9	.	.	PUNCT
admet-2366	82	1	ammonium	ammonium	NOUN
admet-2366	82	2	acetate	acetate	NOUN
admet-2366	82	3	and	and	CCONJ
admet-2366	82	4	acetonitrile	acetonitrile	NOUN
admet-2366	82	5	(	(	PUNCT
admet-2366	82	6	hplc	hplc	NOUN
admet-2366	82	7	-	-	PUNCT
admet-2366	82	8	grade	grade	NOUN
admet-2366	82	9	)	)	PUNCT
admet-2366	82	10	were	be	AUX
admet-2366	82	11	procured	procure	VERB
admet-2366	82	12	from	from	ADP
admet-2366	82	13	rankem	rankem	PROPN
admet-2366	82	14	,	,	PUNCT
admet-2366	82	15	india	india	PROPN
admet-2366	82	16	,	,	PUNCT
admet-2366	82	17	and	and	CCONJ
admet-2366	82	18	fisher	fisher	PROPN
admet-2366	82	19	scientific	scientific	PROPN
admet-2366	82	20	,	,	PUNCT
admet-2366	82	21	mumbai	mumbai	PROPN
admet-2366	82	22	,	,	PUNCT
admet-2366	82	23	respectively	respectively	ADV
admet-2366	82	24	.	.	PUNCT
admet-2366	83	1	human	human	ADJ
admet-2366	83	2	lung	lung	NOUN
admet-2366	83	3	carcinoma	carcinoma	NOUN
admet-2366	83	4	cells	cell	NOUN
admet-2366	83	5	(	(	PUNCT
admet-2366	83	6	a549	a549	PROPN
admet-2366	83	7	and	and	CCONJ
admet-2366	83	8	h1299	h1299	NUM
admet-2366	83	9	)	)	PUNCT
admet-2366	83	10	were	be	AUX
admet-2366	83	11	provided	provide	VERB
admet-2366	83	12	by	by	ADP
admet-2366	83	13	the	the	DET
admet-2366	83	14	national	national	ADJ
admet-2366	83	15	cell	cell	NOUN
admet-2366	83	16	repository	repository	NOUN
admet-2366	83	17	,	,	PUNCT
admet-2366	83	18	pune	pune	NOUN
admet-2366	83	19	,	,	PUNCT
admet-2366	83	20	india	india	PROPN
admet-2366	83	21	.	.	PUNCT
admet-2366	84	1	each	each	DET
admet-2366	84	2	ingredient	ingredient	NOUN
admet-2366	84	3	used	use	VERB
admet-2366	84	4	in	in	ADP
admet-2366	84	5	the	the	DET
admet-2366	84	6	research	research	NOUN
admet-2366	84	7	was	be	AUX
admet-2366	84	8	of	of	ADP
admet-2366	84	9	analytical	analytical	ADJ
admet-2366	84	10	grade	grade	NOUN
admet-2366	84	11	.	.	PUNCT
admet-2366	85	1	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PROPN
admet-2366	85	2	s.	s.	PROPN
admet-2366	85	3	rohilla	rohilla	PROPN
admet-2366	85	4	et	et	PROPN
admet-2366	85	5	al	al	PROPN
admet-2366	85	6	.	.	PROPN
admet-2366	85	7	admet	admet	PROPN
admet-2366	85	8	&	&	CCONJ
admet-2366	85	9	dmpk	dmpk	PROPN
admet-2366	85	10	12(4	12(4	PROPN
admet-2366	85	11	)	)	PUNCT
admet-2366	85	12	(	(	PUNCT
admet-2366	85	13	2024	2024	NUM
admet-2366	85	14	)	)	PUNCT
admet-2366	85	15	657	657	NUM
admet-2366	85	16	-	-	SYM
admet-2366	85	17	677	677	NUM
admet-2366	85	18	660	660	NUM
admet-2366	85	19	preparation	preparation	NOUN
admet-2366	85	20	of	of	ADP
admet-2366	85	21	gefitinib	gefitinib	NOUN
admet-2366	85	22	-	-	PUNCT
admet-2366	85	23	loaded	load	VERB
admet-2366	85	24	nanoliposomes	nanoliposome	NOUN
admet-2366	85	25	and	and	CCONJ
admet-2366	85	26	coating	coat	VERB
admet-2366	85	27	gefitinib	gefitinib	NOUN
admet-2366	85	28	-	-	PUNCT
admet-2366	85	29	loaded	load	VERB
admet-2366	85	30	nanoliposomes	nanoliposome	NOUN
admet-2366	85	31	were	be	AUX
admet-2366	85	32	formulated	formulate	VERB
admet-2366	85	33	by	by	ADP
admet-2366	85	34	the	the	DET
admet-2366	85	35	reverse	reverse	NOUN
admet-2366	85	36	-	-	PUNCT
admet-2366	85	37	phase	phase	NOUN
admet-2366	85	38	evaporation	evaporation	NOUN
admet-2366	85	39	technique	technique	NOUN
admet-2366	85	40	using	use	VERB
admet-2366	85	41	bbd	bbd	PROPN
admet-2366	85	42	.	.	PUNCT
admet-2366	86	1	soya	soya	PROPN
admet-2366	86	2	phosphatidylcholine	phosphatidylcholine	PROPN
admet-2366	86	3	and	and	CCONJ
admet-2366	86	4	cholesterol	cholesterol	NOUN
admet-2366	86	5	were	be	AUX
admet-2366	86	6	liquefied	liquefy	VERB
admet-2366	86	7	in	in	ADP
admet-2366	86	8	diethyl	diethyl	NOUN
admet-2366	86	9	ether	ether	NOUN
admet-2366	86	10	.	.	PUNCT
admet-2366	87	1	gefitinib	gefitinib	NOUN
admet-2366	87	2	was	be	AUX
admet-2366	87	3	dissolved	dissolve	VERB
admet-2366	87	4	in	in	ADP
admet-2366	87	5	distilled	distil	VERB
admet-2366	87	6	water	water	NOUN
admet-2366	87	7	using	use	VERB
admet-2366	87	8	ethanol	ethanol	NOUN
admet-2366	87	9	as	as	ADP
admet-2366	87	10	a	a	DET
admet-2366	87	11	cosolvent	cosolvent	NOUN
admet-2366	87	12	.	.	PUNCT
admet-2366	88	1	the	the	DET
admet-2366	88	2	aqueous	aqueous	ADJ
admet-2366	88	3	and	and	CCONJ
admet-2366	88	4	organic	organic	ADJ
admet-2366	88	5	parts	part	NOUN
admet-2366	88	6	were	be	AUX
admet-2366	88	7	mixed	mix	VERB
admet-2366	88	8	,	,	PUNCT
admet-2366	88	9	followed	follow	VERB
admet-2366	88	10	by	by	ADP
admet-2366	88	11	ultrasonication	ultrasonication	NOUN
admet-2366	88	12	with	with	ADP
admet-2366	88	13	a	a	DET
admet-2366	88	14	probe	probe	NOUN
admet-2366	88	15	sonicator	sonicator	NOUN
admet-2366	88	16	(	(	PUNCT
admet-2366	88	17	sonics	sonics	NOUN
admet-2366	88	18	vibra	vibra	NOUN
admet-2366	88	19	cell	cell	PROPN
admet-2366	88	20	,	,	PUNCT
admet-2366	88	21	usa	usa	PROPN
admet-2366	88	22	,	,	PUNCT
admet-2366	88	23	vcx750w	vcx750w	PRON
admet-2366	88	24	)	)	PUNCT
admet-2366	88	25	on	on	ADP
admet-2366	88	26	an	an	DET
admet-2366	88	27	ice	ice	NOUN
admet-2366	88	28	bath	bath	NOUN
admet-2366	88	29	for	for	ADP
admet-2366	88	30	5	5	NUM
admet-2366	88	31	min	min	NOUN
admet-2366	88	32	with	with	ADP
admet-2366	88	33	1	1	NUM
admet-2366	88	34	s	s	PART
admet-2366	88	35	on	on	ADP
admet-2366	88	36	and	and	CCONJ
admet-2366	88	37	1	1	NUM
admet-2366	88	38	s	s	PART
admet-2366	88	39	off	off	ADP
admet-2366	88	40	intermission	intermission	NOUN
admet-2366	88	41	.	.	PUNCT
admet-2366	89	1	the	the	DET
admet-2366	89	2	round	round	ADJ
admet-2366	89	3	-	-	PUNCT
admet-2366	89	4	bottom	bottom	NOUN
admet-2366	89	5	flask	flask	NOUN
admet-2366	89	6	in	in	ADP
admet-2366	89	7	the	the	DET
admet-2366	89	8	rotary	rotary	ADJ
admet-2366	89	9	evaporator	evaporator	NOUN
admet-2366	89	10	was	be	AUX
admet-2366	89	11	used	use	VERB
admet-2366	89	12	to	to	PART
admet-2366	89	13	transfer	transfer	VERB
admet-2366	89	14	the	the	DET
admet-2366	89	15	consequential	consequential	ADJ
admet-2366	89	16	emulsion	emulsion	NOUN
admet-2366	89	17	and	and	CCONJ
admet-2366	89	18	to	to	PART
admet-2366	89	19	convert	convert	VERB
admet-2366	89	20	it	it	PRON
admet-2366	89	21	into	into	ADP
admet-2366	89	22	gel	gel	NOUN
admet-2366	89	23	under	under	ADP
admet-2366	89	24	reduced	reduce	VERB
admet-2366	89	25	pressure	pressure	NOUN
admet-2366	89	26	at	at	ADP
admet-2366	89	27	40	40	NUM
admet-2366	89	28	°	°	NOUN
admet-2366	89	29	c	c	NOUN
admet-2366	89	30	.	.	NOUN
admet-2366	89	31	ten	ten	NUM
admet-2366	89	32	millilitres	millilitre	NOUN
admet-2366	89	33	of	of	ADP
admet-2366	89	34	phosphate	phosphate	ADJ
admet-2366	89	35	buffer	buffer	NOUN
admet-2366	89	36	(	(	PUNCT
admet-2366	89	37	0.10	0.10	NUM
admet-2366	89	38	m	m	NOUN
admet-2366	89	39	,	,	PUNCT
admet-2366	89	40	ph	ph	NOUN
admet-2366	89	41	7.0	7.0	NUM
admet-2366	89	42	)	)	PUNCT
admet-2366	89	43	containing	contain	VERB
admet-2366	89	44	tween	tween	NOUN
admet-2366	89	45	80	80	NUM
admet-2366	89	46	was	be	AUX
admet-2366	89	47	poured	pour	VERB
admet-2366	89	48	into	into	ADP
admet-2366	89	49	a	a	DET
admet-2366	89	50	round	round	ADJ
admet-2366	89	51	-	-	PUNCT
admet-2366	89	52	bottom	bottom	NOUN
admet-2366	89	53	flask	flask	NOUN
admet-2366	89	54	with	with	ADP
admet-2366	89	55	moderate	moderate	ADJ
admet-2366	89	56	vortexing	vortexing	NOUN
admet-2366	89	57	to	to	PART
admet-2366	89	58	break	break	VERB
admet-2366	89	59	the	the	DET
admet-2366	89	60	gel	gel	NOUN
admet-2366	89	61	into	into	ADP
admet-2366	89	62	liposomes	liposome	NOUN
admet-2366	89	63	under	under	ADP
admet-2366	89	64	the	the	DET
admet-2366	89	65	atmosphere	atmosphere	NOUN
admet-2366	89	66	of	of	ADP
admet-2366	89	67	nitrogen	nitrogen	NOUN
admet-2366	89	68	gas	gas	NOUN
admet-2366	89	69	at	at	ADP
admet-2366	89	70	room	room	NOUN
admet-2366	89	71	temperature	temperature	NOUN
admet-2366	89	72	to	to	PART
admet-2366	89	73	relinquish	relinquish	VERB
admet-2366	89	74	the	the	DET
admet-2366	89	75	resting	rest	VERB
admet-2366	89	76	fumes	fume	NOUN
admet-2366	89	77	of	of	ADP
admet-2366	89	78	diethyl	diethyl	NOUN
admet-2366	89	79	ether	ether	NOUN
admet-2366	89	80	.	.	PUNCT
admet-2366	90	1	the	the	DET
admet-2366	90	2	liposomes	liposome	NOUN
admet-2366	90	3	were	be	AUX
admet-2366	90	4	then	then	ADV
admet-2366	90	5	reduced	reduce	VERB
admet-2366	90	6	to	to	PART
admet-2366	90	7	nanosize	nanosize	VERB
admet-2366	90	8	by	by	ADP
admet-2366	90	9	ultrasonication	ultrasonication	NOUN
admet-2366	90	10	on	on	ADP
admet-2366	90	11	an	an	DET
admet-2366	90	12	ice	ice	NOUN
admet-2366	90	13	bath	bath	NOUN
admet-2366	90	14	with	with	ADP
admet-2366	90	15	a	a	DET
admet-2366	90	16	probe	probe	NOUN
admet-2366	90	17	sonicator	sonicator	NOUN
admet-2366	90	18	for	for	ADP
admet-2366	90	19	10	10	NUM
admet-2366	90	20	minutes	minute	NOUN
admet-2366	90	21	with	with	ADP
admet-2366	90	22	1	1	NUM
admet-2366	90	23	s	s	NOUN
admet-2366	90	24	on	on	ADP
admet-2366	90	25	and	and	CCONJ
admet-2366	90	26	1	1	NUM
admet-2366	90	27	s	s	PART
admet-2366	90	28	off	off	ADP
admet-2366	90	29	intermission	intermission	NOUN
admet-2366	90	30	.	.	PUNCT
admet-2366	91	1	the	the	DET
admet-2366	91	2	product	product	NOUN
admet-2366	91	3	was	be	AUX
admet-2366	91	4	centrifuged	centrifuge	VERB
admet-2366	91	5	at	at	ADP
admet-2366	91	6	3500	3500	NUM
admet-2366	91	7	rpm	rpm	NOUN
admet-2366	91	8	for	for	ADP
admet-2366	91	9	20	20	NUM
admet-2366	91	10	min	min	NOUN
admet-2366	91	11	,	,	PUNCT
admet-2366	91	12	following	follow	VERB
admet-2366	91	13	an	an	DET
admet-2366	91	14	incubation	incubation	NOUN
admet-2366	91	15	period	period	NOUN
admet-2366	91	16	of	of	ADP
admet-2366	91	17	12	12	NUM
admet-2366	91	18	h	h	NOUN
admet-2366	91	19	at	at	ADP
admet-2366	91	20	room	room	NOUN
admet-2366	91	21	temperature	temperature	NOUN
admet-2366	92	1	[	[	X
admet-2366	92	2	35,36	35,36	NUM
admet-2366	92	3	]	]	PUNCT
admet-2366	92	4	.	.	PUNCT
admet-2366	93	1	the	the	DET
admet-2366	93	2	sterile	sterile	ADJ
admet-2366	93	3	,	,	PUNCT
admet-2366	93	4	double	double	ADJ
admet-2366	93	5	-	-	PUNCT
admet-2366	93	6	distilled	distil	VERB
admet-2366	93	7	,	,	PUNCT
admet-2366	93	8	deionized	deionize	VERB
admet-2366	93	9	water	water	NOUN
admet-2366	93	10	is	be	AUX
admet-2366	93	11	used	use	VERB
admet-2366	93	12	to	to	PART
admet-2366	93	13	wash	wash	VERB
admet-2366	93	14	the	the	DET
admet-2366	93	15	pellets	pellet	NOUN
admet-2366	93	16	and	and	CCONJ
admet-2366	93	17	then	then	ADV
admet-2366	93	18	centrifuged	centrifuge	VERB
admet-2366	93	19	.	.	PUNCT
admet-2366	94	1	after	after	ADP
admet-2366	94	2	subsequent	subsequent	ADJ
admet-2366	94	3	washing	washing	NOUN
admet-2366	94	4	and	and	CCONJ
admet-2366	94	5	centrifugation	centrifugation	NOUN
admet-2366	94	6	,	,	PUNCT
admet-2366	94	7	the	the	DET
admet-2366	94	8	resulting	result	VERB
admet-2366	94	9	product	product	NOUN
admet-2366	94	10	was	be	AUX
admet-2366	94	11	re	re	VERB
admet-2366	94	12	-	-	VERB
admet-2366	94	13	suspended	suspend	VERB
admet-2366	94	14	in	in	ADP
admet-2366	94	15	sterilized	sterilize	VERB
admet-2366	94	16	,	,	PUNCT
admet-2366	94	17	double	double	ADJ
admet-2366	94	18	-	-	PUNCT
admet-2366	94	19	distilled	distil	VERB
admet-2366	94	20	,	,	PUNCT
admet-2366	94	21	deionized	deionize	VERB
admet-2366	94	22	water	water	NOUN
admet-2366	94	23	.	.	PUNCT
admet-2366	95	1	the	the	DET
admet-2366	95	2	best	well	ADV
admet-2366	95	3	-	-	PUNCT
admet-2366	95	4	selected	select	VERB
admet-2366	95	5	nanoliposomes	nanoliposome	NOUN
admet-2366	95	6	were	be	AUX
admet-2366	95	7	surface	surface	NOUN
admet-2366	95	8	adorned	adorn	VERB
admet-2366	95	9	(	(	PUNCT
admet-2366	95	10	coated	coat	VERB
admet-2366	95	11	)	)	PUNCT
admet-2366	95	12	by	by	ADP
admet-2366	95	13	magnetically	magnetically	ADV
admet-2366	95	14	stirring	stir	VERB
admet-2366	95	15	a	a	DET
admet-2366	95	16	suitable	suitable	ADJ
admet-2366	95	17	amount	amount	NOUN
admet-2366	95	18	of	of	ADP
admet-2366	95	19	chitosan	chitosan	ADJ
admet-2366	95	20	solution	solution	NOUN
admet-2366	95	21	(	(	PUNCT
admet-2366	95	22	0.01	0.01	NUM
admet-2366	95	23	%	%	NOUN
admet-2366	95	24	w	w	NOUN
admet-2366	95	25	/	/	SYM
admet-2366	95	26	v	v	NOUN
admet-2366	95	27	)	)	PUNCT
admet-2366	95	28	into	into	ADP
admet-2366	95	29	the	the	DET
admet-2366	95	30	nanoliposomal	nanoliposomal	ADJ
admet-2366	95	31	suspension	suspension	NOUN
admet-2366	95	32	.	.	PUNCT
admet-2366	96	1	after	after	ADP
admet-2366	96	2	1	1	NUM
admet-2366	96	3	hour	hour	NOUN
admet-2366	96	4	of	of	ADP
admet-2366	96	5	stirring	stirring	NOUN
admet-2366	96	6	,	,	PUNCT
admet-2366	96	7	the	the	DET
admet-2366	96	8	product	product	NOUN
admet-2366	96	9	was	be	AUX
admet-2366	96	10	incubated	incubate	VERB
admet-2366	96	11	overnight	overnight	ADV
admet-2366	96	12	at	at	ADP
admet-2366	96	13	4	4	NUM
admet-2366	96	14	°	°	NOUN
admet-2366	96	15	c	c	NOUN
admet-2366	96	16	[	[	X
admet-2366	96	17	37,38	37,38	NOUN
admet-2366	96	18	]	]	PUNCT
admet-2366	96	19	.	.	PUNCT
admet-2366	97	1	box	box	NOUN
admet-2366	97	2	-	-	PUNCT
admet-2366	97	3	behnken	behnken	VERB
admet-2366	97	4	design	design	NOUN
admet-2366	97	5	the	the	DET
admet-2366	97	6	bbd	bbd	PROPN
admet-2366	97	7	was	be	AUX
admet-2366	97	8	used	use	VERB
admet-2366	97	9	to	to	PART
admet-2366	97	10	study	study	VERB
admet-2366	97	11	the	the	DET
admet-2366	97	12	effect	effect	NOUN
admet-2366	97	13	of	of	ADP
admet-2366	97	14	three	three	NUM
admet-2366	97	15	independent	independent	ADJ
admet-2366	97	16	variables	variable	NOUN
admet-2366	97	17	:	:	PUNCT
admet-2366	97	18	x1	x1	NUM
admet-2366	97	19	sonication	sonication	NOUN
admet-2366	97	20	time	time	NOUN
admet-2366	97	21	,	,	PUNCT
admet-2366	97	22	min	min	PROPN
admet-2366	97	23	,	,	PUNCT
admet-2366	97	24	x2	x2	PROPN
admet-2366	97	25	tween	tween	NOUN
admet-2366	97	26	80	80	NUM
admet-2366	97	27	/	/	SYM
admet-2366	97	28	soya	soya	NOUN
admet-2366	97	29	lecithin	lecithin	NOUN
admet-2366	97	30	weight	weight	NOUN
admet-2366	97	31	ratio	ratio	NOUN
admet-2366	97	32	,	,	PUNCT
admet-2366	97	33	w	w	PROPN
admet-2366	97	34	/	/	SYM
admet-2366	97	35	w	w	PROPN
admet-2366	97	36	,	,	PUNCT
admet-2366	97	37	and	and	CCONJ
admet-2366	97	38	x3	x3	ADJ
admet-2366	97	39	–	–	PUNCT
admet-2366	97	40	cholesterol	cholesterol	NOUN
admet-2366	97	41	/	/	SYM
admet-2366	97	42	soya	soya	NOUN
admet-2366	97	43	lecithin	lecithin	NOUN
admet-2366	97	44	weight	weight	NOUN
admet-2366	97	45	ratio	ratio	NOUN
admet-2366	97	46	,	,	PUNCT
admet-2366	97	47	on	on	ADP
admet-2366	97	48	two	two	NUM
admet-2366	97	49	dependent	dependent	ADJ
admet-2366	97	50	variables	variable	NOUN
admet-2366	97	51	:	:	PUNCT
admet-2366	97	52	y1	y1	NOUN
admet-2366	97	53	particle	particle	NOUN
admet-2366	97	54	size	size	NOUN
admet-2366	97	55	and	and	CCONJ
admet-2366	97	56	y2	y2	NOUN
admet-2366	97	57	encapsulation	encapsulation	NOUN
admet-2366	97	58	efficiency	efficiency	NOUN
admet-2366	97	59	.	.	PUNCT
admet-2366	98	1	mathematical	mathematical	ADJ
admet-2366	98	2	model	model	NOUN
admet-2366	98	3	bbd	bbd	PROPN
admet-2366	98	4	is	be	AUX
admet-2366	98	5	a	a	DET
admet-2366	98	6	specially	specially	ADV
admet-2366	98	7	designed	design	VERB
admet-2366	98	8	model	model	NOUN
admet-2366	98	9	for	for	ADP
admet-2366	98	10	the	the	DET
admet-2366	98	11	response	response	NOUN
admet-2366	98	12	surface	surface	NOUN
admet-2366	98	13	methodology	methodology	NOUN
admet-2366	98	14	.	.	PUNCT
admet-2366	99	1	every	every	DET
admet-2366	99	2	factor	factor	NOUN
admet-2366	99	3	requires	require	VERB
admet-2366	99	4	only	only	ADV
admet-2366	99	5	three	three	NUM
admet-2366	99	6	levels	level	NOUN
admet-2366	99	7	to	to	PART
admet-2366	99	8	fit	fit	VERB
admet-2366	99	9	in	in	ADP
admet-2366	99	10	a	a	DET
admet-2366	99	11	second	second	ADJ
admet-2366	99	12	-	-	PUNCT
admet-2366	99	13	order	order	NOUN
admet-2366	99	14	regression	regression	NOUN
admet-2366	99	15	(	(	PUNCT
admet-2366	99	16	quadratic	quadratic	ADJ
admet-2366	99	17	)	)	PUNCT
admet-2366	99	18	model	model	NOUN
admet-2366	99	19	.	.	PUNCT
admet-2366	100	1	the	the	DET
admet-2366	100	2	bbd	bbd	PROPN
admet-2366	100	3	sets	set	VERB
admet-2366	100	4	an	an	DET
admet-2366	100	5	intermediate	intermediate	ADJ
admet-2366	100	6	level	level	NOUN
admet-2366	100	7	of	of	ADP
admet-2366	100	8	factors	factor	NOUN
admet-2366	100	9	,	,	PUNCT
admet-2366	100	10	avoiding	avoid	VERB
admet-2366	100	11	the	the	DET
admet-2366	100	12	extreme	extreme	ADJ
admet-2366	100	13	axial	axial	ADJ
admet-2366	100	14	(	(	PUNCT
admet-2366	100	15	star	star	NOUN
admet-2366	100	16	)	)	PUNCT
admet-2366	100	17	points	point	NOUN
admet-2366	100	18	as	as	ADP
admet-2366	100	19	in	in	ADP
admet-2366	100	20	the	the	DET
admet-2366	100	21	central	central	ADJ
admet-2366	100	22	composite	composite	ADJ
admet-2366	100	23	design	design	NOUN
admet-2366	100	24	(	(	PUNCT
admet-2366	100	25	ccd	ccd	NOUN
admet-2366	100	26	)	)	PUNCT
admet-2366	100	27	.	.	PUNCT
admet-2366	101	1	furthermore	furthermore	ADV
admet-2366	101	2	,	,	PUNCT
admet-2366	101	3	the	the	DET
admet-2366	101	4	bbd	bbd	PROPN
admet-2366	101	5	uses	use	VERB
admet-2366	101	6	facade	facade	NOUN
admet-2366	101	7	points	point	NOUN
admet-2366	101	8	that	that	PRON
admet-2366	101	9	are	be	AUX
admet-2366	101	10	more	more	ADV
admet-2366	101	11	realistic	realistic	ADJ
admet-2366	101	12	than	than	SCONJ
admet-2366	101	13	the	the	DET
admet-2366	101	14	corner	corner	NOUN
admet-2366	101	15	points	point	NOUN
admet-2366	101	16	in	in	ADP
admet-2366	101	17	the	the	DET
admet-2366	101	18	ccd	ccd	NOUN
admet-2366	101	19	.	.	PUNCT
admet-2366	102	1	the	the	DET
admet-2366	102	2	number	number	NOUN
admet-2366	102	3	of	of	ADP
admet-2366	102	4	experimental	experimental	ADJ
admet-2366	102	5	runs	run	NOUN
admet-2366	102	6	is	be	AUX
admet-2366	102	7	small	small	ADJ
admet-2366	102	8	.	.	PUNCT
admet-2366	103	1	for	for	ADP
admet-2366	103	2	analysis	analysis	NOUN
admet-2366	103	3	,	,	PUNCT
admet-2366	103	4	the	the	DET
admet-2366	103	5	bbd	bbd	PROPN
admet-2366	103	6	required	require	VERB
admet-2366	103	7	three	three	NUM
admet-2366	103	8	factors	factor	NOUN
admet-2366	103	9	at	at	ADP
admet-2366	103	10	three	three	NUM
admet-2366	103	11	levels	level	NOUN
admet-2366	103	12	.	.	PUNCT
admet-2366	104	1	it	it	PRON
admet-2366	104	2	is	be	AUX
admet-2366	104	3	critical	critical	ADJ
admet-2366	104	4	to	to	PART
admet-2366	104	5	identify	identify	VERB
admet-2366	104	6	appropriate	appropriate	ADJ
admet-2366	104	7	estimation	estimation	NOUN
admet-2366	104	8	methods	method	NOUN
admet-2366	104	9	to	to	PART
admet-2366	104	10	compute	compute	VERB
admet-2366	104	11	the	the	DET
admet-2366	104	12	useful	useful	ADJ
admet-2366	104	13	relationship	relationship	NOUN
admet-2366	104	14	between	between	ADP
admet-2366	104	15	the	the	DET
admet-2366	104	16	response	response	NOUN
admet-2366	104	17	surface	surface	NOUN
admet-2366	104	18	and	and	CCONJ
admet-2366	104	19	independent	independent	ADJ
admet-2366	104	20	variables	variable	NOUN
admet-2366	104	21	.	.	PUNCT
admet-2366	105	1	generally	generally	ADV
admet-2366	105	2	,	,	PUNCT
admet-2366	105	3	a	a	DET
admet-2366	105	4	second	second	ADJ
admet-2366	105	5	-	-	PUNCT
admet-2366	105	6	order	order	NOUN
admet-2366	105	7	polynomial	polynomial	ADJ
admet-2366	105	8	equation	equation	NOUN
admet-2366	105	9	is	be	AUX
admet-2366	105	10	used	use	VERB
admet-2366	105	11	in	in	ADP
admet-2366	105	12	response	response	NOUN
admet-2366	105	13	surface	surface	NOUN
admet-2366	105	14	methodology	methodology	NOUN
admet-2366	105	15	and	and	CCONJ
admet-2366	105	16	is	be	AUX
admet-2366	105	17	expressed	express	VERB
admet-2366	105	18	as	as	ADP
admet-2366	105	19	equation	equation	NOUN
admet-2366	105	20	1	1	NUM
admet-2366	106	1	[	[	SYM
admet-2366	106	2	26	26	NUM
admet-2366	106	3	-	-	SYM
admet-2366	106	4	28	28	NUM
admet-2366	106	5	]	]	PUNCT
admet-2366	106	6	:	:	PUNCT
admet-2366	106	7	y	y	PROPN
admet-2366	106	8	=	=	SYM
admet-2366	106	9	b0	b0	PROPN
admet-2366	106	10	+	+	CCONJ
admet-2366	106	11	b1x1	b1x1	NOUN
admet-2366	106	12	+	+	SYM
admet-2366	106	13	b2x2	b2x2	NOUN
admet-2366	106	14	+	+	NUM
admet-2366	106	15	b3x3	b3x3	X
admet-2366	106	16	+	+	X
admet-2366	106	17	b4x1	b4x1	PROPN
admet-2366	106	18	2	2	NUM
admet-2366	106	19	+	+	CCONJ
admet-2366	106	20	b5x2	b5x2	X
admet-2366	106	21	2	2	NUM
admet-2366	106	22	+	+	CCONJ
admet-2366	106	23	b6x3	b6x3	X
admet-2366	106	24	2	2	NUM
admet-2366	106	25	+	+	NUM
admet-2366	106	26	b7x1x2	b7x1x2	X
admet-2366	106	27	+	+	CCONJ
admet-2366	106	28	b8x1x3	b8x1x3	NOUN
admet-2366	106	29	+	+	CCONJ
admet-2366	106	30	b9x2x3	b9x2x3	X
admet-2366	106	31	(	(	PUNCT
admet-2366	106	32	1	1	NUM
admet-2366	106	33	)	)	PUNCT
admet-2366	106	34	where	where	SCONJ
admet-2366	106	35	y	y	PROPN
admet-2366	106	36	is	be	AUX
admet-2366	106	37	the	the	DET
admet-2366	106	38	level	level	NOUN
admet-2366	106	39	of	of	ADP
admet-2366	106	40	the	the	DET
admet-2366	106	41	response	response	NOUN
admet-2366	106	42	variable	variable	NOUN
admet-2366	106	43	.	.	PUNCT
admet-2366	107	1	b0	b0	NOUN
admet-2366	107	2	is	be	AUX
admet-2366	107	3	the	the	DET
admet-2366	107	4	value	value	NOUN
admet-2366	107	5	of	of	ADP
admet-2366	107	6	the	the	DET
admet-2366	107	7	desired	desire	VERB
admet-2366	107	8	response	response	NOUN
admet-2366	107	9	at	at	ADP
admet-2366	107	10	the	the	DET
admet-2366	107	11	center	center	ADJ
admet-2366	107	12	point	point	NOUN
admet-2366	107	13	of	of	ADP
admet-2366	107	14	the	the	DET
admet-2366	107	15	design	design	NOUN
admet-2366	107	16	.	.	PUNCT
admet-2366	108	1	b1	b1	PROPN
admet-2366	108	2	,	,	PUNCT
admet-2366	108	3	b2	b2	NOUN
admet-2366	108	4	,	,	PUNCT
admet-2366	108	5	and	and	CCONJ
admet-2366	108	6	b3	b3	PROPN
admet-2366	108	7	,	,	PUNCT
admet-2366	108	8	are	be	AUX
admet-2366	108	9	regression	regression	NOUN
admet-2366	108	10	coefficients	coefficient	NOUN
admet-2366	108	11	of	of	ADP
admet-2366	108	12	linear	linear	ADJ
admet-2366	108	13	terms	term	NOUN
admet-2366	108	14	.	.	PUNCT
admet-2366	109	1	b4	b4	NOUN
admet-2366	109	2	,	,	PUNCT
admet-2366	109	3	b5	b5	PROPN
admet-2366	109	4	,	,	PUNCT
admet-2366	109	5	and	and	CCONJ
admet-2366	109	6	b6	b6	NOUN
admet-2366	109	7	are	be	AUX
admet-2366	109	8	regression	regression	NOUN
admet-2366	109	9	coefficients	coefficient	NOUN
admet-2366	109	10	of	of	ADP
admet-2366	109	11	quadratic	quadratic	ADJ
admet-2366	109	12	terms	term	NOUN
admet-2366	109	13	.	.	PUNCT
admet-2366	110	1	b7	b7	PROPN
admet-2366	110	2	,	,	PUNCT
admet-2366	110	3	b8	b8	PROPN
admet-2366	110	4	,	,	PUNCT
admet-2366	110	5	and	and	CCONJ
admet-2366	110	6	b9	b9	PROPN
admet-2366	110	7	are	be	AUX
admet-2366	110	8	the	the	DET
admet-2366	110	9	regression	regression	NOUN
admet-2366	110	10	coefficients	coefficient	NOUN
admet-2366	110	11	of	of	ADP
admet-2366	110	12	interaction	interaction	NOUN
admet-2366	110	13	terms	term	NOUN
admet-2366	110	14	.	.	PUNCT
admet-2366	111	1	x1	x1	NUM
admet-2366	111	2	,	,	PUNCT
admet-2366	111	3	x2	x2	PROPN
admet-2366	111	4	,	,	PUNCT
admet-2366	111	5	and	and	CCONJ
admet-2366	111	6	x3	x3	PROPN
admet-2366	111	7	are	be	AUX
admet-2366	111	8	the	the	DET
admet-2366	111	9	dimensionless	dimensionless	NOUN
admet-2366	111	10	coded	code	VERB
admet-2366	111	11	variables	variable	NOUN
admet-2366	111	12	.	.	PUNCT
admet-2366	112	1	the	the	DET
admet-2366	112	2	second	second	ADJ
admet-2366	112	3	-	-	PUNCT
admet-2366	112	4	order	order	NOUN
admet-2366	112	5	model	model	NOUN
admet-2366	112	6	includes	include	VERB
admet-2366	112	7	all	all	DET
admet-2366	112	8	terms	term	NOUN
admet-2366	112	9	of	of	ADP
admet-2366	112	10	the	the	DET
admet-2366	112	11	first	first	ADJ
admet-2366	112	12	-	-	PUNCT
admet-2366	112	13	order	order	NOUN
admet-2366	112	14	model	model	NOUN
admet-2366	112	15	,	,	PUNCT
admet-2366	112	16	along	along	ADP
admet-2366	112	17	with	with	ADP
admet-2366	112	18	all	all	DET
admet-2366	112	19	quadratic	quadratic	ADJ
admet-2366	112	20	terms	term	NOUN
admet-2366	112	21	like	like	ADP
admet-2366	112	22	b4x1	b4x1	ADP
admet-2366	112	23	2	2	NUM
admet-2366	112	24	and	and	CCONJ
admet-2366	112	25	all	all	DET
admet-2366	112	26	cross	cross	ADJ
admet-2366	112	27	-	-	ADJ
admet-2366	112	28	product	product	ADJ
admet-2366	112	29	terms	term	NOUN
admet-2366	112	30	like	like	ADP
admet-2366	112	31	b8x1x3	b8x1x3	NOUN
admet-2366	112	32	.	.	PUNCT
admet-2366	113	1	characterization	characterization	NOUN
admet-2366	113	2	of	of	ADP
admet-2366	113	3	nanoliposomes	nanoliposome	NOUN
admet-2366	113	4	encapsulation	encapsulation	NOUN
admet-2366	113	5	efficiency	efficiency	NOUN
admet-2366	113	6	and	and	CCONJ
admet-2366	113	7	loading	loading	NOUN
admet-2366	113	8	efficiency	efficiency	NOUN
admet-2366	113	9	to	to	PART
admet-2366	113	10	determine	determine	VERB
admet-2366	113	11	the	the	DET
admet-2366	113	12	percentage	percentage	NOUN
admet-2366	113	13	of	of	ADP
admet-2366	113	14	encapsulated	encapsulate	VERB
admet-2366	113	15	drug	drug	NOUN
admet-2366	113	16	,	,	PUNCT
admet-2366	113	17	nanoliposomes	nanoliposome	NOUN
admet-2366	113	18	were	be	AUX
admet-2366	113	19	mixed	mix	VERB
admet-2366	113	20	with	with	ADP
admet-2366	113	21	alcohol	alcohol	NOUN
admet-2366	113	22	and	and	CCONJ
admet-2366	113	23	sonicated	sonicate	VERB
admet-2366	113	24	.	.	PUNCT
admet-2366	114	1	after	after	ADP
admet-2366	114	2	dilution	dilution	NOUN
admet-2366	114	3	with	with	ADP
admet-2366	114	4	the	the	DET
admet-2366	114	5	mobile	mobile	ADJ
admet-2366	114	6	phase	phase	NOUN
admet-2366	114	7	in	in	ADP
admet-2366	114	8	1:1	1:1	NUM
admet-2366	114	9	fraction	fraction	NOUN
admet-2366	114	10	,	,	PUNCT
admet-2366	114	11	the	the	DET
admet-2366	114	12	samples	sample	NOUN
admet-2366	114	13	were	be	AUX
admet-2366	114	14	centrifuged	centrifuge	VERB
admet-2366	114	15	at	at	ADP
admet-2366	114	16	10,000	10,000	NUM
admet-2366	114	17	rpm	rpm	NOUN
admet-2366	114	18	for	for	ADP
admet-2366	114	19	5	5	NUM
admet-2366	114	20	minutes	minute	NOUN
admet-2366	114	21	.	.	PUNCT
admet-2366	115	1	the	the	DET
admet-2366	115	2	quantity	quantity	NOUN
admet-2366	115	3	of	of	ADP
admet-2366	115	4	drug	drug	NOUN
admet-2366	115	5	was	be	AUX
admet-2366	115	6	analysed	analyse	VERB
admet-2366	115	7	using	use	VERB
admet-2366	115	8	high	high	ADJ
admet-2366	115	9	-	-	PUNCT
admet-2366	115	10	performance	performance	NOUN
admet-2366	115	11	liquid	liquid	ADJ
admet-2366	115	12	chromatography	chromatography	NOUN
admet-2366	115	13	(	(	PUNCT
admet-2366	115	14	hplc	hplc	PROPN
admet-2366	115	15	)	)	PUNCT
admet-2366	115	16	admet	admet	PROPN
admet-2366	115	17	&	&	CCONJ
admet-2366	115	18	dmpk	dmpk	PROPN
admet-2366	115	19	12(4	12(4	PROPN
admet-2366	115	20	)	)	PUNCT
admet-2366	115	21	(	(	PUNCT
admet-2366	115	22	2024	2024	NUM
admet-2366	115	23	)	)	PUNCT
admet-2366	115	24	657	657	NUM
admet-2366	115	25	-	-	SYM
admet-2366	115	26	677	677	NUM
admet-2366	115	27	optimizing	optimizing	NOUN
admet-2366	115	28	gefitinib	gefitinib	NOUN
admet-2366	115	29	nanoliposomes	nanoliposomes	ADV
admet-2366	115	30	doi	doi	ADV
admet-2366	115	31	:	:	PUNCT
admet-2366	115	32	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PRON
admet-2366	115	33	661	661	NUM
admet-2366	115	34	(	(	PUNCT
admet-2366	115	35	agilent	agilent	PROPN
admet-2366	115	36	technologies	technology	NOUN
admet-2366	115	37	1200	1200	NUM
admet-2366	115	38	series	series	NOUN
admet-2366	115	39	,	,	PUNCT
admet-2366	115	40	germany	germany	PROPN
admet-2366	115	41	;	;	PUNCT
admet-2366	115	42	quaternary	quaternary	ADJ
admet-2366	115	43	pump	pump	NOUN
admet-2366	115	44	;	;	PUNCT
admet-2366	115	45	eclipse	eclipse	NOUN
admet-2366	115	46	xdb	xdb	VERB
admet-2366	115	47	-	-	PUNCT
admet-2366	115	48	c18	c18	NOUN
admet-2366	115	49	column	column	NOUN
admet-2366	115	50	(	(	PUNCT
admet-2366	115	51	4.6×150	4.6×150	NOUN
admet-2366	115	52	mm	mm	X
admet-2366	115	53	)	)	PUNCT
admet-2366	115	54	packed	pack	VERB
admet-2366	115	55	with	with	ADP
admet-2366	115	56	octadecylsilane	octadecylsilane	NOUN
admet-2366	115	57	and	and	CCONJ
admet-2366	115	58	porous	porous	ADJ
admet-2366	115	59	silica	silica	NOUN
admet-2366	115	60	(	(	PUNCT
admet-2366	115	61	3	3	NUM
admet-2366	115	62	μm	μm	NUM
admet-2366	115	63	)	)	PUNCT
admet-2366	115	64	at	at	ADP
admet-2366	115	65	254	254	NUM
admet-2366	115	66	nm	nm	NOUN
admet-2366	115	67	.	.	PUNCT
admet-2366	116	1	the	the	DET
admet-2366	116	2	mobile	mobile	ADJ
admet-2366	116	3	phase	phase	NOUN
admet-2366	116	4	consisting	consist	VERB
admet-2366	116	5	of	of	ADP
admet-2366	116	6	1	1	NUM
admet-2366	116	7	%	%	NOUN
admet-2366	116	8	ammonium	ammonium	NOUN
admet-2366	116	9	acetate	acetate	NOUN
admet-2366	116	10	and	and	CCONJ
admet-2366	116	11	acetonitrile	acetonitrile	NOUN
admet-2366	116	12	at	at	ADP
admet-2366	116	13	2:3	2:3	NUM
admet-2366	116	14	ratio	ratio	NOUN
admet-2366	116	15	was	be	AUX
admet-2366	116	16	analyzed	analyze	VERB
admet-2366	116	17	at	at	ADP
admet-2366	116	18	a	a	DET
admet-2366	116	19	1	1	NUM
admet-2366	116	20	ml	ml	NOUN
admet-2366	116	21	/	/	SYM
admet-2366	116	22	min	min	NOUN
admet-2366	116	23	flow	flow	NOUN
admet-2366	116	24	rate	rate	NOUN
admet-2366	116	25	.	.	PUNCT
admet-2366	117	1	the	the	DET
admet-2366	117	2	temperature	temperature	NOUN
admet-2366	117	3	was	be	AUX
admet-2366	117	4	maintained	maintain	VERB
admet-2366	117	5	at	at	ADP
admet-2366	117	6	25	25	NUM
admet-2366	117	7	°	°	NOUN
admet-2366	117	8	c	c	NOUN
admet-2366	117	9	[	[	X
admet-2366	117	10	39,40	39,40	NUM
admet-2366	117	11	]	]	PUNCT
admet-2366	117	12	.	.	PUNCT
admet-2366	118	1	the	the	DET
admet-2366	118	2	test	test	NOUN
admet-2366	118	3	sample	sample	NOUN
admet-2366	118	4	was	be	AUX
admet-2366	118	5	introduced	introduce	VERB
admet-2366	118	6	via	via	ADP
admet-2366	118	7	a	a	DET
admet-2366	118	8	microsyringe	microsyringe	NOUN
admet-2366	118	9	and	and	CCONJ
admet-2366	118	10	examined	examine	VERB
admet-2366	118	11	at	at	ADP
admet-2366	118	12	254	254	NUM
admet-2366	118	13	nm	nm	NOUN
admet-2366	118	14	.	.	PUNCT
admet-2366	119	1	equations	equation	NOUN
admet-2366	119	2	2	2	NUM
admet-2366	119	3	and	and	CCONJ
admet-2366	119	4	3	3	NUM
admet-2366	119	5	were	be	AUX
admet-2366	119	6	used	use	VERB
admet-2366	119	7	to	to	PART
admet-2366	119	8	calculate	calculate	VERB
admet-2366	119	9	the	the	DET
admet-2366	119	10	percentage	percentage	NOUN
admet-2366	119	11	encapsulation	encapsulation	NOUN
admet-2366	119	12	efficiency	efficiency	NOUN
admet-2366	119	13	and	and	CCONJ
admet-2366	119	14	percentage	percentage	NOUN
admet-2366	119	15	loading	loading	NOUN
admet-2366	119	16	,	,	PUNCT
admet-2366	119	17	respectively	respectively	ADV
admet-2366	119	18	:	:	PUNCT
admet-2366	119	19	encapsulation	encapsulation	NOUN
admet-2366	119	20	efficiency	efficiency	NOUN
admet-2366	119	21	,	,	PUNCT
admet-2366	119	22	%	%	NOUN
admet-2366	119	23	=	=	SYM
admet-2366	119	24	(	(	PUNCT
admet-2366	119	25	amount	amount	NOUN
admet-2366	119	26	of	of	ADP
admet-2366	119	27	total	total	ADJ
admet-2366	119	28	drugamount	drugamount	NOUN
admet-2366	119	29	of	of	ADP
admet-2366	119	30	free	free	ADJ
admet-2366	119	31	drug	drug	NOUN
admet-2366	119	32	/	/	SYM
admet-2366	119	33	amount	amount	NOUN
admet-2366	119	34	of	of	ADP
admet-2366	119	35	total	total	ADJ
admet-2366	119	36	drug	drug	NOUN
admet-2366	119	37	)	)	PUNCT
admet-2366	119	38	×	×	NOUN
admet-2366	119	39	100	100	NUM
admet-2366	119	40	(	(	PUNCT
admet-2366	119	41	2	2	NUM
admet-2366	119	42	)	)	PUNCT
admet-2366	119	43	loading	loading	NOUN
admet-2366	119	44	efficiency	efficiency	NOUN
admet-2366	119	45	,	,	PUNCT
admet-2366	119	46	%	%	NOUN
admet-2366	119	47	=	=	SYM
admet-2366	119	48	(	(	PUNCT
admet-2366	119	49	amount	amount	NOUN
admet-2366	119	50	of	of	ADP
admet-2366	119	51	total	total	ADJ
admet-2366	119	52	drugamount	drugamount	NOUN
admet-2366	119	53	of	of	ADP
admet-2366	119	54	free	free	ADJ
admet-2366	119	55	drug/	drug/	NUM
admet-2366	119	56	lipid	lipid	NOUN
admet-2366	119	57	content	content	NOUN
admet-2366	119	58	)	)	PUNCT
admet-2366	119	59	×	×	NOUN
admet-2366	119	60	100	100	NUM
admet-2366	119	61	(	(	PUNCT
admet-2366	119	62	3	3	NUM
admet-2366	119	63	)	)	PUNCT
admet-2366	119	64	determination	determination	NOUN
admet-2366	119	65	of	of	ADP
admet-2366	119	66	particle	particle	NOUN
admet-2366	119	67	size	size	NOUN
admet-2366	119	68	,	,	PUNCT
admet-2366	119	69	polydispersity	polydispersity	NOUN
admet-2366	119	70	index	index	NOUN
admet-2366	119	71	and	and	CCONJ
admet-2366	119	72	zeta	zeta	NOUN
admet-2366	119	73	potential	potential	ADJ
admet-2366	119	74	zeta	zeta	NOUN
admet-2366	119	75	potential	potential	NOUN
admet-2366	119	76	,	,	PUNCT
admet-2366	119	77	mean	mean	ADJ
admet-2366	119	78	particle	particle	NOUN
admet-2366	119	79	size	size	NOUN
admet-2366	119	80	,	,	PUNCT
admet-2366	119	81	and	and	CCONJ
admet-2366	119	82	size	size	NOUN
admet-2366	119	83	distribution	distribution	NOUN
admet-2366	119	84	were	be	AUX
admet-2366	119	85	analysed	analyse	VERB
admet-2366	119	86	by	by	ADP
admet-2366	119	87	quasielastic	quasielastic	ADJ
admet-2366	119	88	laser	laser	NOUN
admet-2366	119	89	light	light	NOUN
admet-2366	119	90	scattering	scattering	NOUN
admet-2366	119	91	using	use	VERB
admet-2366	119	92	a	a	DET
admet-2366	119	93	malvern	malvern	ADJ
admet-2366	119	94	zetasizer	zetasizer	NOUN
admet-2366	119	95	®	®	NOUN
admet-2366	119	96	(	(	PUNCT
admet-2366	119	97	zeta	zeta	PROPN
admet-2366	119	98	sizer	sizer	PROPN
admet-2366	119	99	,	,	PUNCT
admet-2366	119	100	nano	nano	PROPN
admet-2366	119	101	zs90	zs90	PROPN
admet-2366	119	102	,	,	PUNCT
admet-2366	119	103	malvern	malvern	PROPN
admet-2366	119	104	instruments	instrument	NOUN
admet-2366	119	105	,	,	PUNCT
admet-2366	119	106	uk	uk	PROPN
admet-2366	119	107	)	)	PUNCT
admet-2366	119	108	.	.	PUNCT
admet-2366	120	1	the	the	DET
admet-2366	120	2	sample	sample	NOUN
admet-2366	120	3	was	be	AUX
admet-2366	120	4	scanned	scan	VERB
admet-2366	120	5	at	at	ADP
admet-2366	120	6	64	64	NUM
admet-2366	120	7	runs	run	NOUN
admet-2366	120	8	in	in	ADP
admet-2366	120	9	a	a	DET
admet-2366	120	10	polystyrene	polystyrene	NOUN
admet-2366	120	11	cuvette	cuvette	NOUN
admet-2366	120	12	of	of	ADP
admet-2366	120	13	the	the	DET
admet-2366	120	14	hydro	hydro	NOUN
admet-2366	120	15	-	-	PUNCT
admet-2366	120	16	dispersing	disperse	VERB
admet-2366	120	17	unit	unit	NOUN
admet-2366	120	18	of	of	ADP
admet-2366	120	19	zetasizer	zetasizer	NOUN
admet-2366	120	20	to	to	PART
admet-2366	120	21	determine	determine	VERB
admet-2366	120	22	the	the	DET
admet-2366	120	23	particle	particle	NOUN
admet-2366	120	24	dimension	dimension	NOUN
admet-2366	120	25	and	and	CCONJ
admet-2366	120	26	polydispersity	polydispersity	NOUN
admet-2366	120	27	index	index	NOUN
admet-2366	120	28	.	.	PUNCT
admet-2366	121	1	the	the	DET
admet-2366	121	2	particle	particle	NOUN
admet-2366	121	3	size	size	NOUN
admet-2366	121	4	distribution	distribution	NOUN
admet-2366	121	5	was	be	AUX
admet-2366	121	6	estimated	estimate	VERB
admet-2366	121	7	by	by	ADP
admet-2366	121	8	the	the	DET
admet-2366	121	9	polydispersity	polydispersity	NOUN
admet-2366	121	10	index	index	NOUN
admet-2366	121	11	(	(	PUNCT
admet-2366	121	12	pdi	pdi	NOUN
admet-2366	121	13	)	)	PUNCT
admet-2366	121	14	value	value	NOUN
admet-2366	122	1	[	[	X
admet-2366	122	2	41,42	41,42	NOUN
admet-2366	122	3	]	]	PUNCT
admet-2366	122	4	.	.	PUNCT
admet-2366	123	1	differential	differential	PROPN
admet-2366	123	2	scanning	scan	VERB
admet-2366	123	3	calorimetry	calorimetry	NOUN
admet-2366	123	4	a	a	DET
admet-2366	123	5	differential	differential	NOUN
admet-2366	123	6	scanning	scan	VERB
admet-2366	123	7	calorimeter	calorimeter	NOUN
admet-2366	123	8	(	(	PUNCT
admet-2366	123	9	dsc	dsc	NOUN
admet-2366	123	10	)	)	PUNCT
admet-2366	123	11	(	(	PUNCT
admet-2366	123	12	q	q	PROPN
admet-2366	123	13	10	10	NUM
admet-2366	123	14	,	,	PUNCT
admet-2366	123	15	ta	ta	ADP
admet-2366	123	16	instruments	instrument	NOUN
admet-2366	123	17	,	,	PUNCT
admet-2366	123	18	new	new	ADJ
admet-2366	123	19	castle	castle	NOUN
admet-2366	123	20	,	,	PUNCT
admet-2366	123	21	united	united	PROPN
admet-2366	123	22	states	states	PROPN
admet-2366	123	23	)	)	PUNCT
admet-2366	123	24	was	be	AUX
admet-2366	123	25	used	use	VERB
admet-2366	123	26	for	for	ADP
admet-2366	123	27	thermal	thermal	ADJ
admet-2366	123	28	analysis	analysis	NOUN
admet-2366	123	29	to	to	PART
admet-2366	123	30	determine	determine	VERB
admet-2366	123	31	the	the	DET
admet-2366	123	32	melting	melting	NOUN
admet-2366	123	33	point	point	NOUN
admet-2366	123	34	,	,	PUNCT
admet-2366	123	35	purity	purity	NOUN
admet-2366	123	36	,	,	PUNCT
admet-2366	123	37	and	and	CCONJ
admet-2366	123	38	encapsulation	encapsulation	NOUN
admet-2366	123	39	of	of	ADP
admet-2366	123	40	the	the	DET
admet-2366	123	41	drug	drug	NOUN
admet-2366	123	42	in	in	ADP
admet-2366	123	43	nanoliposomes	nanoliposome	NOUN
admet-2366	123	44	before	before	ADV
admet-2366	123	45	and	and	CCONJ
admet-2366	123	46	after	after	ADP
admet-2366	123	47	coating	coating	NOUN
admet-2366	123	48	.	.	PUNCT
admet-2366	124	1	the	the	DET
admet-2366	124	2	apparatus	apparatus	NOUN
admet-2366	124	3	was	be	AUX
admet-2366	124	4	standardized	standardize	VERB
admet-2366	124	5	with	with	ADP
admet-2366	124	6	indium	indium	NOUN
admet-2366	124	7	.	.	PUNCT
admet-2366	125	1	the	the	DET
admet-2366	125	2	aluminium	aluminium	NOUN
admet-2366	125	3	pans	pan	NOUN
admet-2366	125	4	were	be	AUX
admet-2366	125	5	used	use	VERB
admet-2366	125	6	to	to	PART
admet-2366	125	7	load	load	VERB
admet-2366	125	8	the	the	DET
admet-2366	125	9	trial	trial	NOUN
admet-2366	125	10	formulation	formulation	NOUN
admet-2366	125	11	.	.	PUNCT
admet-2366	126	1	the	the	DET
admet-2366	126	2	temperature	temperature	NOUN
admet-2366	126	3	was	be	AUX
admet-2366	126	4	altered	alter	VERB
admet-2366	126	5	progressively	progressively	ADV
admet-2366	126	6	from	from	ADP
admet-2366	126	7	25	25	NUM
admet-2366	126	8	to	to	PART
admet-2366	126	9	300	300	NUM
admet-2366	126	10	°	°	NOUN
admet-2366	126	11	c	c	NOUN
admet-2366	126	12	at	at	ADP
admet-2366	126	13	a	a	DET
admet-2366	126	14	rate	rate	NOUN
admet-2366	126	15	of	of	ADP
admet-2366	126	16	10	10	NUM
admet-2366	126	17	°	°	NOUN
admet-2366	126	18	c	c	NOUN
admet-2366	126	19	/	/	SYM
admet-2366	126	20	min	min	NOUN
admet-2366	126	21	in	in	ADP
admet-2366	126	22	an	an	DET
admet-2366	126	23	atmosphere	atmosphere	NOUN
admet-2366	126	24	of	of	ADP
admet-2366	126	25	nitrogen	nitrogen	NOUN
admet-2366	126	26	(	(	PUNCT
admet-2366	126	27	60	60	NUM
admet-2366	126	28	ml/	ml/	PROPN
admet-2366	126	29	min	min	PROPN
admet-2366	126	30	)	)	PUNCT
admet-2366	126	31	.	.	PUNCT
admet-2366	127	1	an	an	DET
admet-2366	127	2	empty	empty	ADJ
admet-2366	127	3	pan	pan	NOUN
admet-2366	127	4	was	be	AUX
admet-2366	127	5	used	use	VERB
admet-2366	127	6	as	as	ADP
admet-2366	127	7	a	a	DET
admet-2366	127	8	reference	reference	NOUN
admet-2366	127	9	under	under	ADP
admet-2366	127	10	the	the	DET
admet-2366	127	11	same	same	ADJ
admet-2366	127	12	conditions	condition	NOUN
admet-2366	127	13	[	[	X
admet-2366	127	14	42	42	NUM
admet-2366	127	15	]	]	PUNCT
admet-2366	127	16	.	.	PUNCT
admet-2366	128	1	fourier	fourier	PROPN
admet-2366	128	2	transforms	transform	VERB
admet-2366	128	3	infrared	infrared	ADJ
admet-2366	128	4	spectroscopy	spectroscopy	NOUN
admet-2366	128	5	fourier	fourier	NOUN
admet-2366	128	6	transforms	transform	VERB
admet-2366	128	7	infrared	infrared	ADJ
admet-2366	128	8	(	(	PUNCT
admet-2366	128	9	ft	ft	NOUN
admet-2366	128	10	-	-	PUNCT
admet-2366	128	11	ir	ir	NOUN
admet-2366	128	12	)	)	PUNCT
admet-2366	128	13	spectra	spectra	NOUN
admet-2366	128	14	of	of	ADP
admet-2366	128	15	pure	pure	ADJ
admet-2366	128	16	gefitinib	gefitinib	NOUN
admet-2366	128	17	,	,	PUNCT
admet-2366	128	18	gefitinib	gefitinib	NOUN
admet-2366	128	19	-	-	PUNCT
admet-2366	128	20	loaded	load	VERB
admet-2366	128	21	unadorned	unadorned	ADJ
admet-2366	128	22	nanoliposomes	nanoliposome	NOUN
admet-2366	128	23	,	,	PUNCT
admet-2366	128	24	and	and	CCONJ
admet-2366	128	25	surface	surface	NOUN
admet-2366	128	26	-	-	PUNCT
admet-2366	128	27	adorned	adorn	VERB
admet-2366	128	28	nanoliposomes	nanoliposome	NOUN
admet-2366	128	29	were	be	AUX
admet-2366	128	30	recorded	record	VERB
admet-2366	128	31	using	use	VERB
admet-2366	128	32	an	an	DET
admet-2366	128	33	ft	ft	NOUN
admet-2366	128	34	-	-	PUNCT
admet-2366	128	35	ir	ir	NOUN
admet-2366	128	36	-	-	ADJ
admet-2366	128	37	alpha	alpha	ADJ
admet-2366	128	38	bruker	bruker	NOUN
admet-2366	128	39	1206	1206	NUM
admet-2366	128	40	0280	0280	NUM
admet-2366	128	41	.	.	PUNCT
admet-2366	129	1	the	the	DET
admet-2366	129	2	sample	sample	NOUN
admet-2366	129	3	holder	holder	NOUN
admet-2366	129	4	was	be	AUX
admet-2366	129	5	cleaned	clean	VERB
admet-2366	129	6	,	,	PUNCT
admet-2366	129	7	and	and	CCONJ
admet-2366	129	8	background	background	NOUN
admet-2366	129	9	measurements	measurement	NOUN
admet-2366	129	10	were	be	AUX
admet-2366	129	11	done	do	VERB
admet-2366	129	12	to	to	PART
admet-2366	129	13	nullify	nullify	VERB
admet-2366	129	14	the	the	DET
admet-2366	129	15	effect	effect	NOUN
admet-2366	129	16	of	of	ADP
admet-2366	129	17	environmental	environmental	ADJ
admet-2366	129	18	impurities	impurity	NOUN
admet-2366	129	19	.	.	PUNCT
admet-2366	130	1	the	the	DET
admet-2366	130	2	samples	sample	NOUN
admet-2366	130	3	were	be	AUX
admet-2366	130	4	positioned	position	VERB
admet-2366	130	5	on	on	ADP
admet-2366	130	6	a	a	DET
admet-2366	130	7	holder	holder	NOUN
admet-2366	130	8	for	for	ADP
admet-2366	130	9	analysis	analysis	NOUN
admet-2366	130	10	and	and	CCONJ
admet-2366	130	11	scanned	scan	VERB
admet-2366	130	12	from	from	ADP
admet-2366	130	13	400	400	NUM
admet-2366	130	14	to	to	ADP
admet-2366	130	15	4000	4000	NUM
admet-2366	130	16	cm-1	cm-1	VERB
admet-2366	130	17	at	at	ADP
admet-2366	130	18	a	a	DET
admet-2366	130	19	resolution	resolution	NOUN
admet-2366	130	20	of	of	ADP
admet-2366	130	21	4	4	NUM
admet-2366	130	22	cm-1	cm-1	NOUN
admet-2366	131	1	[	[	X
admet-2366	131	2	43	43	NUM
admet-2366	131	3	]	]	PUNCT
admet-2366	131	4	.	.	PUNCT
admet-2366	132	1	morphological	morphological	ADJ
admet-2366	132	2	characterization	characterization	NOUN
admet-2366	132	3	morphological	morphological	ADJ
admet-2366	132	4	characterization	characterization	NOUN
admet-2366	132	5	of	of	ADP
admet-2366	132	6	the	the	DET
admet-2366	132	7	sample	sample	NOUN
admet-2366	132	8	suspension	suspension	NOUN
admet-2366	132	9	was	be	AUX
admet-2366	132	10	done	do	VERB
admet-2366	132	11	using	use	VERB
admet-2366	132	12	a	a	DET
admet-2366	132	13	transmission	transmission	NOUN
admet-2366	132	14	electron	electron	NOUN
admet-2366	132	15	microscope	microscope	NOUN
admet-2366	132	16	(	(	PUNCT
admet-2366	132	17	h-600	h-600	PROPN
admet-2366	132	18	tem	tem	PROPN
admet-2366	132	19	,	,	PUNCT
admet-2366	132	20	hitachi	hitachi	PROPN
admet-2366	132	21	ltd	ltd	PROPN
admet-2366	132	22	.	.	PROPN
admet-2366	132	23	,	,	PUNCT
admet-2366	132	24	tokyo	tokyo	PROPN
admet-2366	132	25	,	,	PUNCT
admet-2366	132	26	japan	japan	PROPN
admet-2366	132	27	)	)	PUNCT
admet-2366	132	28	at	at	ADP
admet-2366	132	29	200	200	NUM
admet-2366	132	30	kv	kv	NOUN
admet-2366	132	31	.	.	PUNCT
admet-2366	133	1	a	a	DET
admet-2366	133	2	drop	drop	NOUN
admet-2366	133	3	of	of	ADP
admet-2366	133	4	the	the	DET
admet-2366	133	5	diluted	diluted	ADJ
admet-2366	133	6	sample	sample	NOUN
admet-2366	133	7	was	be	AUX
admet-2366	133	8	placed	place	VERB
admet-2366	133	9	on	on	ADP
admet-2366	133	10	a	a	DET
admet-2366	133	11	carbon	carbon	NOUN
admet-2366	133	12	-	-	PUNCT
admet-2366	133	13	coated	coat	VERB
admet-2366	133	14	copper	copper	NOUN
admet-2366	133	15	grid	grid	NOUN
admet-2366	133	16	and	and	CCONJ
admet-2366	133	17	dried	dry	VERB
admet-2366	133	18	properly	properly	ADV
admet-2366	133	19	[	[	X
admet-2366	133	20	44	44	NUM
admet-2366	133	21	]	]	PUNCT
admet-2366	133	22	.	.	PUNCT
admet-2366	134	1	determination	determination	NOUN
admet-2366	134	2	of	of	ADP
admet-2366	134	3	gefitinib	gefitinib	NOUN
admet-2366	134	4	release	release	NOUN
admet-2366	134	5	and	and	CCONJ
admet-2366	134	6	release	release	VERB
admet-2366	134	7	kinetics	kinetic	NOUN
admet-2366	134	8	from	from	ADP
admet-2366	134	9	nanoliposomes	nanoliposome	NOUN
admet-2366	134	10	drug	drug	NOUN
admet-2366	134	11	release	release	NOUN
admet-2366	134	12	studies	study	NOUN
admet-2366	134	13	were	be	AUX
admet-2366	134	14	carried	carry	VERB
admet-2366	134	15	out	out	ADP
admet-2366	134	16	using	use	VERB
admet-2366	134	17	a	a	DET
admet-2366	134	18	dialysis	dialysis	NOUN
admet-2366	134	19	bag	bag	NOUN
admet-2366	134	20	method	method	NOUN
admet-2366	134	21	in	in	ADP
admet-2366	134	22	simulated	simulated	ADJ
admet-2366	134	23	intestinal	intestinal	ADJ
admet-2366	134	24	fluid	fluid	NOUN
admet-2366	134	25	(	(	PUNCT
admet-2366	134	26	ph	ph	NOUN
admet-2366	134	27	6.8	6.8	NUM
admet-2366	134	28	)	)	PUNCT
admet-2366	134	29	,	,	PUNCT
admet-2366	134	30	acetate	acetate	NOUN
admet-2366	134	31	buffer	buffer	NOUN
admet-2366	134	32	(	(	PUNCT
admet-2366	134	33	ph	ph	NOUN
admet-2366	134	34	4.0	4.0	NUM
admet-2366	134	35	)	)	PUNCT
admet-2366	134	36	,	,	PUNCT
admet-2366	134	37	and	and	CCONJ
admet-2366	134	38	0.1	0.1	NUM
admet-2366	134	39	n	n	PRON
admet-2366	134	40	hcl	hcl	PROPN
admet-2366	134	41	(	(	PUNCT
admet-2366	134	42	ph	ph	NOUN
admet-2366	134	43	1.2	1.2	NUM
admet-2366	134	44	)	)	PUNCT
admet-2366	135	1	[	[	X
admet-2366	135	2	45	45	NUM
admet-2366	135	3	]	]	PUNCT
admet-2366	135	4	.	.	PUNCT
admet-2366	136	1	gefitinib	gefitinib	NOUN
admet-2366	136	2	-	-	PUNCT
admet-2366	136	3	loaded	load	VERB
admet-2366	136	4	nanoliposomes	nanoliposome	NOUN
admet-2366	136	5	and	and	CCONJ
admet-2366	136	6	surface	surface	NOUN
admet-2366	136	7	-	-	PUNCT
admet-2366	136	8	adorned	adorn	VERB
admet-2366	136	9	nanoliposomes	nanoliposome	NOUN
admet-2366	136	10	(	(	PUNCT
admet-2366	136	11	each	each	PRON
admet-2366	136	12	containing	contain	VERB
admet-2366	136	13	250	250	NUM
admet-2366	136	14	mg	mg	ADP
admet-2366	136	15	of	of	ADP
admet-2366	136	16	the	the	DET
admet-2366	136	17	drug	drug	NOUN
admet-2366	136	18	)	)	PUNCT
admet-2366	136	19	were	be	AUX
admet-2366	136	20	sealed	seal	VERB
admet-2366	136	21	in	in	ADP
admet-2366	136	22	the	the	DET
admet-2366	136	23	preactivated	preactivate	VERB
admet-2366	136	24	dialysis	dialysis	NOUN
admet-2366	136	25	bag	bag	NOUN
admet-2366	136	26	(	(	PUNCT
admet-2366	136	27	molecular	molecular	ADJ
admet-2366	136	28	weight	weight	NOUN
admet-2366	136	29	cutoff	cutoff	NOUN
admet-2366	136	30	,	,	PUNCT
admet-2366	136	31	12,000	12,000	NUM
admet-2366	136	32	da	da	X
admet-2366	136	33	,	,	PUNCT
admet-2366	136	34	himedia	himedia	NOUN
admet-2366	136	35	,	,	PUNCT
admet-2366	136	36	mumbai	mumbai	PROPN
admet-2366	136	37	,	,	PUNCT
admet-2366	136	38	india	india	PROPN
admet-2366	136	39	)	)	PUNCT
admet-2366	136	40	.	.	PUNCT
admet-2366	137	1	a	a	DET
admet-2366	137	2	sample	sample	NOUN
admet-2366	137	3	containing	contain	VERB
admet-2366	137	4	a	a	DET
admet-2366	137	5	dialysis	dialysis	NOUN
admet-2366	137	6	bag	bag	NOUN
admet-2366	137	7	was	be	AUX
admet-2366	137	8	immersed	immerse	VERB
admet-2366	137	9	in	in	ADP
admet-2366	137	10	the	the	DET
admet-2366	137	11	usp	usp	PROPN
admet-2366	137	12	dissolution	dissolution	PROPN
admet-2366	137	13	apparatus	apparatus	PROPN
admet-2366	137	14	ii	ii	PROPN
admet-2366	137	15	(	(	PUNCT
admet-2366	137	16	ds	ds	PROPN
admet-2366	137	17	8000	8000	NUM
admet-2366	137	18	,	,	PUNCT
admet-2366	137	19	lab	lab	PROPN
admet-2366	137	20	india	india	PROPN
admet-2366	137	21	,	,	PUNCT
admet-2366	137	22	mumbai	mumbai	PROPN
admet-2366	137	23	,	,	PUNCT
admet-2366	137	24	india	india	PROPN
admet-2366	137	25	)	)	PUNCT
admet-2366	137	26	containing	contain	VERB
admet-2366	137	27	200	200	NUM
admet-2366	137	28	ml	ml	NOUN
admet-2366	137	29	of	of	ADP
admet-2366	137	30	dissolution	dissolution	ADJ
admet-2366	137	31	medium	medium	NOUN
admet-2366	137	32	.	.	PUNCT
admet-2366	138	1	the	the	DET
admet-2366	138	2	temperature	temperature	NOUN
admet-2366	138	3	was	be	AUX
admet-2366	138	4	kept	keep	VERB
admet-2366	138	5	constant	constant	ADJ
admet-2366	138	6	at	at	ADP
admet-2366	138	7	37±0.5	37±0.5	NUM
admet-2366	138	8	°	°	ADP
admet-2366	138	9	c	c	NOUN
admet-2366	138	10	and	and	CCONJ
admet-2366	138	11	the	the	DET
admet-2366	138	12	paddle	paddle	NOUN
admet-2366	138	13	was	be	AUX
admet-2366	138	14	rotated	rotate	VERB
admet-2366	138	15	at	at	ADP
admet-2366	138	16	100	100	NUM
admet-2366	138	17	rpm	rpm	NOUN
admet-2366	138	18	.	.	PUNCT
admet-2366	139	1	at	at	ADP
admet-2366	139	2	predetermined	predetermine	VERB
admet-2366	139	3	intervals	interval	NOUN
admet-2366	139	4	(	(	PUNCT
admet-2366	139	5	0.5	0.5	NUM
admet-2366	139	6	,	,	PUNCT
admet-2366	139	7	1	1	NUM
admet-2366	139	8	,	,	PUNCT
admet-2366	139	9	2	2	NUM
admet-2366	139	10	,	,	PUNCT
admet-2366	139	11	4	4	NUM
admet-2366	139	12	,	,	PUNCT
admet-2366	139	13	6	6	NUM
admet-2366	139	14	,	,	PUNCT
admet-2366	139	15	8	8	NUM
admet-2366	139	16	,	,	PUNCT
admet-2366	139	17	12	12	NUM
admet-2366	139	18	,	,	PUNCT
admet-2366	139	19	18	18	NUM
admet-2366	139	20	and	and	CCONJ
admet-2366	139	21	24	24	NUM
admet-2366	139	22	h	h	NOUN
admet-2366	139	23	)	)	PUNCT
admet-2366	139	24	,	,	PUNCT
admet-2366	139	25	2	2	NUM
admet-2366	139	26	ml	ml	NOUN
admet-2366	139	27	of	of	ADP
admet-2366	139	28	the	the	DET
admet-2366	139	29	samples	sample	NOUN
admet-2366	139	30	were	be	AUX
admet-2366	139	31	collected	collect	VERB
admet-2366	139	32	.	.	PUNCT
admet-2366	140	1	the	the	DET
admet-2366	140	2	fresh	fresh	ADJ
admet-2366	140	3	preheated	preheated	ADJ
admet-2366	140	4	medium	medium	NOUN
admet-2366	140	5	was	be	AUX
admet-2366	140	6	used	use	VERB
admet-2366	140	7	to	to	PART
admet-2366	140	8	maintain	maintain	VERB
admet-2366	140	9	the	the	DET
admet-2366	140	10	sink	sink	NOUN
admet-2366	140	11	condition	condition	NOUN
admet-2366	140	12	.	.	PUNCT
admet-2366	141	1	following	follow	VERB
admet-2366	141	2	filtration	filtration	NOUN
admet-2366	141	3	via	via	ADP
admet-2366	141	4	a	a	DET
admet-2366	141	5	0.45	0.45	NUM
admet-2366	141	6	µm	µm	ADP
admet-2366	141	7	filter	filter	NOUN
admet-2366	141	8	,	,	PUNCT
admet-2366	141	9	the	the	DET
admet-2366	141	10	samples	sample	NOUN
admet-2366	141	11	were	be	AUX
admet-2366	141	12	analysed	analyse	VERB
admet-2366	141	13	using	use	VERB
admet-2366	141	14	hplc	hplc	NOUN
admet-2366	141	15	(	(	PUNCT
admet-2366	141	16	1200	1200	NUM
admet-2366	141	17	series	series	NOUN
admet-2366	141	18	,	,	PUNCT
admet-2366	141	19	agilent	agilent	PROPN
admet-2366	141	20	technologies	technologies	PROPN
admet-2366	141	21	,	,	PUNCT
admet-2366	141	22	germany	germany	PROPN
admet-2366	141	23	)	)	PUNCT
admet-2366	141	24	at	at	ADP
admet-2366	141	25	254	254	NUM
admet-2366	141	26	nm	nm	NOUN
admet-2366	141	27	.	.	PUNCT
admet-2366	142	1	the	the	DET
admet-2366	142	2	sample	sample	NOUN
admet-2366	142	3	analysis	analysis	NOUN
admet-2366	142	4	was	be	AUX
admet-2366	142	5	done	do	VERB
admet-2366	142	6	in	in	ADP
admet-2366	142	7	triplicate	triplicate	NOUN
admet-2366	142	8	,	,	PUNCT
admet-2366	142	9	and	and	CCONJ
admet-2366	142	10	mean	mean	ADJ
admet-2366	142	11	values	value	NOUN
admet-2366	142	12	were	be	AUX
admet-2366	142	13	used	use	VERB
admet-2366	142	14	for	for	ADP
admet-2366	142	15	estimation	estimation	NOUN
admet-2366	142	16	[	[	X
admet-2366	142	17	46	46	NUM
admet-2366	142	18	]	]	PUNCT
admet-2366	142	19	.	.	PUNCT
admet-2366	143	1	in	in	ADP
admet-2366	143	2	vitro	vitro	X
admet-2366	143	3	drug	drug	NOUN
admet-2366	143	4	release	release	NOUN
admet-2366	143	5	data	datum	NOUN
admet-2366	143	6	was	be	AUX
admet-2366	143	7	fitted	fit	VERB
admet-2366	143	8	into	into	ADP
admet-2366	143	9	zero	zero	NUM
admet-2366	143	10	-	-	PUNCT
admet-2366	143	11	order	order	NOUN
admet-2366	143	12	,	,	PUNCT
admet-2366	143	13	first	first	ADJ
admet-2366	143	14	-	-	PUNCT
admet-2366	143	15	order	order	NOUN
admet-2366	143	16	,	,	PUNCT
admet-2366	143	17	higuchi	higuchi	PROPN
admet-2366	143	18	's	's	PART
admet-2366	143	19	,	,	PUNCT
admet-2366	143	20	and	and	CCONJ
admet-2366	143	21	korsmeyer	korsmeyer	NOUN
admet-2366	143	22	-	-	PUNCT
admet-2366	143	23	peppas	peppas	NOUN
admet-2366	143	24	’	'	PUNCT
admet-2366	143	25	models	model	NOUN
admet-2366	143	26	to	to	PART
admet-2366	143	27	determine	determine	VERB
admet-2366	143	28	drug	drug	NOUN
admet-2366	143	29	release	release	NOUN
admet-2366	143	30	kinetics	kinetic	NOUN
admet-2366	143	31	and	and	CCONJ
admet-2366	143	32	mechanism	mechanism	NOUN
admet-2366	143	33	from	from	ADP
admet-2366	143	34	the	the	DET
admet-2366	143	35	nanovesicles	nanovesicle	NOUN
admet-2366	143	36	[	[	X
admet-2366	143	37	47	47	NUM
admet-2366	143	38	]	]	PUNCT
admet-2366	143	39	.	.	PUNCT
admet-2366	144	1	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PROPN
admet-2366	144	2	s.	s.	PROPN
admet-2366	144	3	rohilla	rohilla	PROPN
admet-2366	144	4	et	et	PROPN
admet-2366	144	5	al	al	PROPN
admet-2366	144	6	.	.	PROPN
admet-2366	144	7	admet	admet	PROPN
admet-2366	144	8	&	&	CCONJ
admet-2366	144	9	dmpk	dmpk	PROPN
admet-2366	144	10	12(4	12(4	PROPN
admet-2366	144	11	)	)	PUNCT
admet-2366	144	12	(	(	PUNCT
admet-2366	144	13	2024	2024	NUM
admet-2366	144	14	)	)	PUNCT
admet-2366	144	15	657	657	NUM
admet-2366	144	16	-	-	SYM
admet-2366	144	17	677	677	NUM
admet-2366	144	18	662	662	NUM
admet-2366	144	19	cytotoxicity	cytotoxicity	NOUN
admet-2366	144	20	study	study	NOUN
admet-2366	144	21	cell	cell	NOUN
admet-2366	144	22	culture	culture	NOUN
admet-2366	144	23	and	and	CCONJ
admet-2366	144	24	treatment	treatment	NOUN
admet-2366	144	25	dulbecco	dulbecco	NOUN
admet-2366	144	26	's	's	PART
admet-2366	144	27	modified	modify	VERB
admet-2366	144	28	eagle	eagle	NOUN
admet-2366	144	29	's	's	PART
admet-2366	144	30	medium	medium	NOUN
admet-2366	144	31	with	with	ADP
admet-2366	144	32	2	2	NUM
admet-2366	144	33	%	%	NOUN
admet-2366	144	34	antibiotics	antibiotic	NOUN
admet-2366	144	35	and	and	CCONJ
admet-2366	144	36	10	10	NUM
admet-2366	144	37	%	%	NOUN
admet-2366	144	38	fetal	fetal	ADJ
admet-2366	144	39	bovine	bovine	NOUN
admet-2366	144	40	serum	serum	NOUN
admet-2366	144	41	was	be	AUX
admet-2366	144	42	used	use	VERB
admet-2366	144	43	to	to	PART
admet-2366	144	44	culture	culture	VERB
admet-2366	144	45	a549	a549	PROPN
admet-2366	144	46	and	and	CCONJ
admet-2366	144	47	h1299	h1299	CCONJ
admet-2366	144	48	human	human	ADJ
admet-2366	144	49	lung	lung	NOUN
admet-2366	144	50	cancer	cancer	NOUN
admet-2366	144	51	cells	cell	NOUN
admet-2366	144	52	.	.	PUNCT
admet-2366	145	1	the	the	DET
admet-2366	145	2	cells	cell	NOUN
admet-2366	145	3	were	be	AUX
admet-2366	145	4	grown	grow	VERB
admet-2366	145	5	at	at	ADP
admet-2366	145	6	37	37	NUM
admet-2366	145	7	°	°	NOUN
admet-2366	145	8	c	c	NOUN
admet-2366	145	9	in	in	ADP
admet-2366	145	10	5	5	NUM
admet-2366	145	11	%	%	NOUN
admet-2366	145	12	co2	co2	NOUN
admet-2366	145	13	and	and	CCONJ
admet-2366	145	14	95	95	NUM
admet-2366	145	15	%	%	NOUN
admet-2366	145	16	humidity	humidity	NOUN
admet-2366	145	17	for	for	ADP
admet-2366	145	18	24	24	NUM
admet-2366	145	19	h.	h.	PROPN
admet-2366	145	20	cells	cell	NOUN
admet-2366	145	21	were	be	AUX
admet-2366	145	22	spread	spread	VERB
admet-2366	145	23	uniformly	uniformly	ADV
admet-2366	145	24	(	(	PUNCT
admet-2366	145	25	8,000	8,000	NUM
admet-2366	145	26	to	to	PART
admet-2366	145	27	10,000	10,000	NUM
admet-2366	145	28	per	per	ADP
admet-2366	145	29	96	96	NUM
admet-2366	145	30	-	-	PUNCT
admet-2366	145	31	well	well	NOUN
admet-2366	145	32	plate	plate	NOUN
admet-2366	145	33	)	)	PUNCT
admet-2366	145	34	.	.	PUNCT
admet-2366	146	1	after	after	ADP
admet-2366	146	2	washing	wash	VERB
admet-2366	146	3	with	with	ADP
admet-2366	146	4	phosphate	phosphate	NOUN
admet-2366	146	5	-	-	PUNCT
admet-2366	146	6	buffered	buffer	VERB
admet-2366	146	7	saline	saline	NOUN
admet-2366	146	8	,	,	PUNCT
admet-2366	146	9	cells	cell	NOUN
admet-2366	146	10	were	be	AUX
admet-2366	146	11	cultured	cultured	ADJ
admet-2366	146	12	in	in	ADP
admet-2366	146	13	a	a	DET
admet-2366	146	14	serum	serum	NOUN
admet-2366	146	15	-	-	PUNCT
admet-2366	146	16	free	free	ADJ
admet-2366	146	17	medium	medium	NOUN
admet-2366	146	18	for	for	ADP
admet-2366	146	19	2	2	NUM
admet-2366	146	20	days	day	NOUN
admet-2366	146	21	.	.	PUNCT
admet-2366	147	1	different	different	ADJ
admet-2366	147	2	concentrations	concentration	NOUN
admet-2366	147	3	(	(	PUNCT
admet-2366	147	4	1	1	NUM
admet-2366	147	5	,	,	PUNCT
admet-2366	147	6	5	5	NUM
admet-2366	147	7	,	,	PUNCT
admet-2366	147	8	and	and	CCONJ
admet-2366	147	9	20	20	NUM
admet-2366	147	10	µm	µm	NOUN
admet-2366	147	11	)	)	PUNCT
admet-2366	147	12	of	of	ADP
admet-2366	147	13	the	the	DET
admet-2366	147	14	samples	sample	NOUN
admet-2366	147	15	were	be	AUX
admet-2366	147	16	mixed	mix	VERB
admet-2366	147	17	with	with	ADP
admet-2366	147	18	dimethyl	dimethyl	NOUN
admet-2366	147	19	sulfoxide	sulfoxide	NOUN
admet-2366	147	20	and	and	CCONJ
admet-2366	147	21	tested	test	VERB
admet-2366	147	22	against	against	ADP
admet-2366	147	23	cancer	cancer	NOUN
admet-2366	147	24	cells	cell	NOUN
admet-2366	147	25	.	.	PUNCT
admet-2366	148	1	pure	pure	ADJ
admet-2366	148	2	drug	drug	NOUN
admet-2366	148	3	was	be	AUX
admet-2366	148	4	used	use	VERB
admet-2366	148	5	as	as	ADP
admet-2366	148	6	a	a	DET
admet-2366	148	7	control	control	NOUN
admet-2366	148	8	.	.	PUNCT
admet-2366	149	1	the	the	DET
admet-2366	149	2	experiment	experiment	NOUN
admet-2366	149	3	was	be	AUX
admet-2366	149	4	conducted	conduct	VERB
admet-2366	149	5	in	in	ADP
admet-2366	149	6	triplicate	triplicate	NOUN
admet-2366	149	7	[	[	X
admet-2366	149	8	48	48	NUM
admet-2366	149	9	]	]	PUNCT
admet-2366	149	10	.	.	PUNCT
admet-2366	150	1	mtt	mtt	PROPN
admet-2366	150	2	assay	assay	VERB
admet-2366	150	3	the	the	DET
admet-2366	150	4	mtt	mtt	NOUN
admet-2366	150	5	(	(	PUNCT
admet-2366	150	6	3-(4	3-(4	NUM
admet-2366	150	7	,	,	PUNCT
admet-2366	150	8	5	5	NUM
admet-2366	150	9	-	-	PUNCT
admet-2366	150	10	dimethylthiazol-2	dimethylthiazol-2	NUM
admet-2366	150	11	-	-	PUNCT
admet-2366	150	12	yl)-2	yl)-2	NOUN
admet-2366	150	13	,	,	PUNCT
admet-2366	150	14	5	5	NUM
admet-2366	150	15	-	-	PUNCT
admet-2366	150	16	diphenyl	diphenyl	NOUN
admet-2366	150	17	tetrazolium	tetrazolium	NOUN
admet-2366	150	18	bromide	bromide	NOUN
admet-2366	150	19	)	)	PUNCT
admet-2366	150	20	assay	assay	NOUN
admet-2366	150	21	was	be	AUX
admet-2366	150	22	carried	carry	VERB
admet-2366	150	23	out	out	ADP
admet-2366	150	24	using	use	VERB
admet-2366	150	25	a	a	DET
admet-2366	150	26	96	96	NUM
admet-2366	150	27	-	-	PUNCT
admet-2366	150	28	well	well	NOUN
admet-2366	150	29	plate	plate	NOUN
admet-2366	150	30	technique	technique	NOUN
admet-2366	151	1	[	[	X
admet-2366	151	2	40,41	40,41	NOUN
admet-2366	151	3	]	]	PUNCT
admet-2366	151	4	.	.	PUNCT
admet-2366	152	1	a549	a549	PROPN
admet-2366	152	2	and	and	CCONJ
admet-2366	152	3	h1299	h1299	NUM
admet-2366	152	4	cells	cell	NOUN
admet-2366	152	5	were	be	AUX
admet-2366	152	6	counted	count	VERB
admet-2366	152	7	using	use	VERB
admet-2366	152	8	an	an	DET
admet-2366	152	9	automated	automate	VERB
admet-2366	152	10	cell	cell	NOUN
admet-2366	152	11	counter	counter	NOUN
admet-2366	152	12	.	.	PUNCT
admet-2366	153	1	the	the	DET
admet-2366	153	2	cells	cell	NOUN
admet-2366	153	3	were	be	AUX
admet-2366	153	4	exposed	expose	VERB
admet-2366	153	5	to	to	ADP
admet-2366	153	6	synthetic	synthetic	ADJ
admet-2366	153	7	chemicals	chemical	NOUN
admet-2366	153	8	for	for	ADP
admet-2366	153	9	two	two	NUM
admet-2366	153	10	days	day	NOUN
admet-2366	153	11	after	after	ADP
admet-2366	153	12	being	be	AUX
admet-2366	153	13	seeded	seed	VERB
admet-2366	153	14	with	with	ADP
admet-2366	153	15	approximately	approximately	ADV
admet-2366	153	16	8,000	8,000	NUM
admet-2366	153	17	to	to	PART
admet-2366	153	18	10,000	10,000	NUM
admet-2366	153	19	cells	cell	NOUN
admet-2366	153	20	in	in	ADP
admet-2366	153	21	each	each	DET
admet-2366	153	22	well	well	NOUN
admet-2366	153	23	of	of	ADP
admet-2366	153	24	the	the	DET
admet-2366	153	25	96	96	NUM
admet-2366	153	26	-	-	PUNCT
admet-2366	153	27	well	well	NOUN
admet-2366	153	28	plates	plate	NOUN
admet-2366	153	29	and	and	CCONJ
admet-2366	153	30	100	100	NUM
admet-2366	153	31	µl	µl	NOUN
admet-2366	153	32	of	of	ADP
admet-2366	153	33	media	medium	NOUN
admet-2366	153	34	in	in	ADP
admet-2366	153	35	each	each	DET
admet-2366	153	36	space	space	NOUN
admet-2366	153	37	.	.	PUNCT
admet-2366	154	1	after	after	ADP
admet-2366	154	2	two	two	NUM
admet-2366	154	3	days	day	NOUN
admet-2366	154	4	,	,	PUNCT
admet-2366	154	5	the	the	DET
admet-2366	154	6	media	medium	NOUN
admet-2366	154	7	was	be	AUX
admet-2366	154	8	removed	remove	VERB
admet-2366	154	9	and	and	CCONJ
admet-2366	154	10	washed	wash	VERB
admet-2366	154	11	with	with	ADP
admet-2366	154	12	phosphate	phosphate	NOUN
admet-2366	154	13	-	-	PUNCT
admet-2366	154	14	buffered	buffer	VERB
admet-2366	154	15	saline	saline	NOUN
admet-2366	154	16	.	.	PUNCT
admet-2366	155	1	the	the	DET
admet-2366	155	2	cells	cell	NOUN
admet-2366	155	3	were	be	AUX
admet-2366	155	4	treated	treat	VERB
admet-2366	155	5	with	with	ADP
admet-2366	155	6	doses	dose	NOUN
admet-2366	155	7	of	of	ADP
admet-2366	155	8	1	1	NUM
admet-2366	155	9	µm	µm	NOUN
admet-2366	155	10	,	,	PUNCT
admet-2366	155	11	5	5	NUM
admet-2366	155	12	µm	µm	NOUN
admet-2366	155	13	,	,	PUNCT
admet-2366	155	14	and	and	CCONJ
admet-2366	155	15	25	25	NUM
admet-2366	155	16	µm	µm	NOUN
admet-2366	155	17	and	and	CCONJ
admet-2366	155	18	after	after	ADP
admet-2366	155	19	1	1	NUM
admet-2366	155	20	day	day	NOUN
admet-2366	155	21	,	,	PUNCT
admet-2366	155	22	and	and	CCONJ
admet-2366	155	23	they	they	PRON
admet-2366	155	24	were	be	AUX
admet-2366	155	25	incubated	incubate	VERB
admet-2366	155	26	for	for	ADP
admet-2366	155	27	48	48	NUM
admet-2366	155	28	h.	h.	PROPN
admet-2366	155	29	media	medium	NOUN
admet-2366	155	30	was	be	AUX
admet-2366	155	31	replaced	replace	VERB
admet-2366	155	32	with	with	ADP
admet-2366	155	33	10	10	NUM
admet-2366	155	34	µl	µl	NOUN
admet-2366	155	35	of	of	ADP
admet-2366	155	36	mtt	mtt	NOUN
admet-2366	155	37	solution	solution	NOUN
admet-2366	155	38	(	(	PUNCT
admet-2366	155	39	5	5	NUM
admet-2366	155	40	mg/	mg/	NOUN
admet-2366	155	41	10	10	NUM
admet-2366	155	42	ml	ml	NOUN
admet-2366	155	43	of	of	ADP
admet-2366	155	44	phosphate	phosphate	NOUN
admet-2366	155	45	-	-	PUNCT
admet-2366	155	46	buffered	buffer	VERB
admet-2366	155	47	saline	saline	NOUN
admet-2366	155	48	)	)	PUNCT
admet-2366	155	49	and	and	CCONJ
admet-2366	155	50	then	then	ADV
admet-2366	155	51	left	leave	VERB
admet-2366	155	52	to	to	PART
admet-2366	155	53	incubate	incubate	VERB
admet-2366	155	54	for	for	ADP
admet-2366	155	55	4	4	NUM
admet-2366	155	56	hours	hour	NOUN
admet-2366	155	57	in	in	ADP
admet-2366	155	58	the	the	DET
admet-2366	155	59	dark	dark	NOUN
admet-2366	155	60	.	.	PUNCT
admet-2366	156	1	the	the	DET
admet-2366	156	2	mtt	mtt	NOUN
admet-2366	156	3	solution	solution	NOUN
admet-2366	156	4	was	be	AUX
admet-2366	156	5	then	then	ADV
admet-2366	156	6	removed	remove	VERB
admet-2366	156	7	from	from	ADP
admet-2366	156	8	each	each	PRON
admet-2366	156	9	well	well	NOUN
admet-2366	156	10	,	,	PUNCT
admet-2366	156	11	100	100	NUM
admet-2366	156	12	µl	µl	ADP
admet-2366	156	13	of	of	ADP
admet-2366	156	14	dimethyl	dimethyl	NOUN
admet-2366	156	15	sulfoxide	sulfoxide	NOUN
admet-2366	156	16	solution	solution	NOUN
admet-2366	156	17	was	be	AUX
admet-2366	156	18	added	add	VERB
admet-2366	156	19	to	to	ADP
admet-2366	156	20	the	the	DET
admet-2366	156	21	intracellular	intracellular	ADJ
admet-2366	156	22	precipitates	precipitate	NOUN
admet-2366	156	23	,	,	PUNCT
admet-2366	156	24	and	and	CCONJ
admet-2366	156	25	the	the	DET
admet-2366	156	26	absorbance	absorbance	NOUN
admet-2366	156	27	of	of	ADP
admet-2366	156	28	the	the	DET
admet-2366	156	29	violet	violet	ADJ
admet-2366	156	30	hue	hue	NOUN
admet-2366	156	31	created	create	VERB
admet-2366	156	32	by	by	ADP
admet-2366	156	33	the	the	DET
admet-2366	156	34	addition	addition	NOUN
admet-2366	156	35	of	of	ADP
admet-2366	156	36	dimethyl	dimethyl	NOUN
admet-2366	156	37	sulfoxide	sulfoxide	NOUN
admet-2366	156	38	was	be	AUX
admet-2366	156	39	measured	measure	VERB
admet-2366	156	40	spectrophotometrically	spectrophotometrically	ADV
admet-2366	156	41	at	at	ADP
admet-2366	156	42	570	570	NUM
admet-2366	156	43	nm	nm	NOUN
admet-2366	156	44	.	.	PUNCT
admet-2366	157	1	half	half	NOUN
admet-2366	157	2	of	of	ADP
admet-2366	157	3	the	the	DET
admet-2366	157	4	inhibitory	inhibitory	ADJ
admet-2366	157	5	concentration	concentration	NOUN
admet-2366	157	6	(	(	PUNCT
admet-2366	157	7	ic50	ic50	PROPN
admet-2366	157	8	)	)	PUNCT
admet-2366	157	9	,	,	PUNCT
admet-2366	157	10	at	at	ADP
admet-2366	157	11	which	which	PRON
admet-2366	157	12	50	50	NUM
admet-2366	157	13	%	%	NOUN
admet-2366	157	14	of	of	ADP
admet-2366	157	15	the	the	DET
admet-2366	157	16	cells	cell	NOUN
admet-2366	157	17	were	be	AUX
admet-2366	157	18	confirmed	confirm	VERB
admet-2366	157	19	to	to	PART
admet-2366	157	20	be	be	AUX
admet-2366	157	21	viable	viable	ADJ
admet-2366	157	22	,	,	PUNCT
admet-2366	157	23	was	be	AUX
admet-2366	157	24	used	use	VERB
admet-2366	157	25	to	to	PART
admet-2366	157	26	represent	represent	VERB
admet-2366	157	27	the	the	DET
admet-2366	157	28	study	study	NOUN
admet-2366	157	29	results	result	NOUN
admet-2366	157	30	.	.	PUNCT
admet-2366	158	1	the	the	DET
admet-2366	158	2	proportion	proportion	NOUN
admet-2366	158	3	of	of	ADP
admet-2366	158	4	viable	viable	ADJ
admet-2366	158	5	cells	cell	NOUN
admet-2366	158	6	was	be	AUX
admet-2366	158	7	calculated	calculate	VERB
admet-2366	158	8	using	use	VERB
admet-2366	158	9	equation	equation	NOUN
admet-2366	158	10	4	4	NUM
admet-2366	159	1	[	[	X
admet-2366	159	2	49	49	NUM
admet-2366	159	3	]	]	PUNCT
admet-2366	159	4	.	.	PUNCT
admet-2366	160	1	cell	cell	NOUN
admet-2366	160	2	viability	viability	NOUN
admet-2366	160	3	=	=	PUNCT
admet-2366	160	4	(	(	PUNCT
admet-2366	160	5	average	average	ADJ
admet-2366	160	6	optical	optical	ADJ
admet-2366	160	7	density	density	NOUN
admet-2366	160	8	of	of	ADP
admet-2366	160	9	individual	individual	ADJ
admet-2366	160	10	test	test	NOUN
admet-2366	160	11	group	group	NOUN
admet-2366	160	12	/	/	SYM
admet-2366	160	13	average	average	ADJ
admet-2366	160	14	optical	optical	ADJ
admet-2366	160	15	density	density	NOUN
admet-2366	160	16	of	of	ADP
admet-2366	160	17	control	control	NOUN
admet-2366	160	18	group	group	PROPN
admet-2366	160	19	)	)	PUNCT
admet-2366	160	20	×	×	NOUN
admet-2366	160	21	100	100	NUM
admet-2366	160	22	(	(	PUNCT
admet-2366	160	23	4	4	X
admet-2366	160	24	)	)	PUNCT
admet-2366	160	25	stability	stability	NOUN
admet-2366	160	26	studies	study	NOUN
admet-2366	160	27	of	of	ADP
admet-2366	160	28	nanoliposomal	nanoliposomal	ADJ
admet-2366	160	29	system	system	NOUN
admet-2366	160	30	the	the	DET
admet-2366	160	31	samples	sample	NOUN
admet-2366	160	32	were	be	AUX
admet-2366	160	33	stored	store	VERB
admet-2366	160	34	at	at	ADP
admet-2366	160	35	different	different	ADJ
admet-2366	160	36	temperatures	temperature	NOUN
admet-2366	160	37	according	accord	VERB
admet-2366	160	38	to	to	ADP
admet-2366	160	39	ich	ich	NOUN
admet-2366	160	40	guidelines	guideline	NOUN
admet-2366	160	41	for	for	ADP
admet-2366	160	42	six	six	NUM
admet-2366	160	43	months	month	NOUN
admet-2366	160	44	to	to	PART
admet-2366	160	45	determine	determine	VERB
admet-2366	160	46	the	the	DET
admet-2366	160	47	stability	stability	NOUN
admet-2366	160	48	of	of	ADP
admet-2366	160	49	the	the	DET
admet-2366	160	50	unadorned	unadorned	ADJ
admet-2366	160	51	and	and	CCONJ
admet-2366	160	52	surface	surface	NOUN
admet-2366	160	53	-	-	PUNCT
admet-2366	160	54	adorned	adorn	VERB
admet-2366	160	55	nanoliposomal	nanoliposomal	ADJ
admet-2366	160	56	preparations	preparation	NOUN
admet-2366	160	57	,	,	PUNCT
admet-2366	160	58	including	include	VERB
admet-2366	160	59	freeze	freeze	VERB
admet-2366	160	60	temperature	temperature	NOUN
admet-2366	160	61	(	(	PUNCT
admet-2366	160	62	4±1	4±1	NOUN
admet-2366	160	63	°	°	NOUN
admet-2366	160	64	c	c	NOUN
admet-2366	160	65	)	)	PUNCT
admet-2366	160	66	,	,	PUNCT
admet-2366	160	67	room	room	NOUN
admet-2366	160	68	temperature	temperature	NOUN
admet-2366	160	69	(	(	PUNCT
admet-2366	160	70	25±2	25±2	NOUN
admet-2366	160	71	°	°	ADP
admet-2366	160	72	c	c	NOUN
admet-2366	160	73	/	/	SYM
admet-2366	160	74	60±5	60±5	NOUN
admet-2366	160	75	%	%	NOUN
admet-2366	160	76	of	of	ADP
admet-2366	160	77	relative	relative	ADJ
admet-2366	160	78	humidity	humidity	NOUN
admet-2366	160	79	(	(	PUNCT
admet-2366	160	80	rh	rh	PROPN
admet-2366	160	81	)	)	PUNCT
admet-2366	160	82	,	,	PUNCT
admet-2366	160	83	and	and	CCONJ
admet-2366	160	84	higher	high	ADJ
admet-2366	160	85	temperature	temperature	NOUN
admet-2366	160	86	(	(	PUNCT
admet-2366	160	87	45±2	45±2	PROPN
admet-2366	160	88	°	°	PROPN
admet-2366	160	89	c/	c/	NOUN
admet-2366	160	90	75±5	75±5	NUM
admet-2366	160	91	%	%	NOUN
admet-2366	160	92	rh	rh	NOUN
admet-2366	160	93	)	)	PUNCT
admet-2366	160	94	.	.	PUNCT
admet-2366	161	1	the	the	DET
admet-2366	161	2	storage	storage	NOUN
admet-2366	161	3	stability	stability	NOUN
admet-2366	161	4	was	be	AUX
admet-2366	161	5	assessed	assess	VERB
admet-2366	161	6	by	by	ADP
admet-2366	161	7	monitoring	monitor	VERB
admet-2366	161	8	changes	change	NOUN
admet-2366	161	9	in	in	ADP
admet-2366	161	10	the	the	DET
admet-2366	161	11	percentage	percentage	NOUN
admet-2366	161	12	of	of	ADP
admet-2366	161	13	encapsulation	encapsulation	NOUN
admet-2366	161	14	,	,	PUNCT
admet-2366	161	15	particle	particle	NOUN
admet-2366	161	16	size	size	NOUN
admet-2366	161	17	,	,	PUNCT
admet-2366	161	18	and	and	CCONJ
admet-2366	161	19	physical	physical	ADJ
admet-2366	161	20	appearance	appearance	NOUN
admet-2366	161	21	[	[	X
admet-2366	161	22	36,39	36,39	ADJ
admet-2366	161	23	]	]	PUNCT
admet-2366	161	24	.	.	PUNCT
admet-2366	162	1	results	result	NOUN
admet-2366	162	2	loading	loading	NOUN
admet-2366	162	3	efficiency	efficiency	NOUN
admet-2366	162	4	,	,	PUNCT
admet-2366	162	5	entrapment	entrapment	ADJ
admet-2366	162	6	efficiency	efficiency	NOUN
admet-2366	162	7	,	,	PUNCT
admet-2366	162	8	and	and	CCONJ
admet-2366	162	9	drug	drug	NOUN
admet-2366	162	10	content	content	NOUN
admet-2366	162	11	loading	loading	NOUN
admet-2366	162	12	efficiency	efficiency	NOUN
admet-2366	162	13	,	,	PUNCT
admet-2366	162	14	encapsulation	encapsulation	NOUN
admet-2366	162	15	efficiency	efficiency	NOUN
admet-2366	162	16	,	,	PUNCT
admet-2366	162	17	and	and	CCONJ
admet-2366	162	18	drug	drug	NOUN
admet-2366	162	19	content	content	NOUN
admet-2366	162	20	ranged	range	VERB
admet-2366	162	21	from	from	ADP
admet-2366	162	22	24.50±0.33	24.50±0.33	NUM
admet-2366	162	23	to	to	ADP
admet-2366	162	24	34.91±0.32	34.91±0.32	NUM
admet-2366	162	25	%	%	NOUN
admet-2366	162	26	,	,	PUNCT
admet-2366	162	27	47.00±0.13	47.00±0.13	NUM
admet-2366	162	28	to	to	ADP
admet-2366	162	29	87.56±0.17	87.56±0.17	NUM
admet-2366	162	30	%	%	NOUN
admet-2366	162	31	,	,	PUNCT
admet-2366	162	32	and	and	CCONJ
admet-2366	162	33	50.23±0.38	50.23±0.38	NUM
admet-2366	162	34	to	to	ADP
admet-2366	162	35	89.76±0.51	89.76±0.51	NUM
admet-2366	162	36	%	%	NOUN
admet-2366	162	37	,	,	PUNCT
admet-2366	162	38	respectively	respectively	ADV
admet-2366	162	39	(	(	PUNCT
admet-2366	162	40	table	table	NOUN
admet-2366	162	41	1	1	NUM
admet-2366	162	42	)	)	PUNCT
admet-2366	162	43	.	.	PUNCT
admet-2366	163	1	formulation	formulation	NOUN
admet-2366	163	2	ng13	ng13	PROPN
admet-2366	163	3	had	have	VERB
admet-2366	163	4	the	the	DET
admet-2366	163	5	maximum	maximum	ADJ
admet-2366	163	6	loading	loading	NOUN
admet-2366	163	7	and	and	CCONJ
admet-2366	163	8	encapsulation	encapsulation	NOUN
admet-2366	163	9	efficiencies	efficiency	NOUN
admet-2366	163	10	(	(	PUNCT
admet-2366	163	11	34.91±0.32	34.91±0.32	NUM
admet-2366	163	12	and	and	CCONJ
admet-2366	163	13	87.56±0.17	87.56±0.17	NUM
admet-2366	163	14	%	%	NOUN
admet-2366	163	15	,	,	PUNCT
admet-2366	163	16	respectively	respectively	ADV
admet-2366	163	17	)	)	PUNCT
admet-2366	163	18	.	.	PUNCT
admet-2366	164	1	figures	figure	NOUN
admet-2366	164	2	1	1	NUM
admet-2366	164	3	and	and	CCONJ
admet-2366	164	4	2	2	NUM
admet-2366	164	5	display	display	VERB
admet-2366	164	6	the	the	DET
admet-2366	164	7	pareto	pareto	ADJ
admet-2366	164	8	chart	chart	NOUN
admet-2366	164	9	,	,	PUNCT
admet-2366	164	10	3d	3d	ADJ
admet-2366	164	11	-	-	PUNCT
admet-2366	164	12	response	response	NOUN
admet-2366	164	13	surface	surface	NOUN
admet-2366	164	14	plots	plot	NOUN
admet-2366	164	15	,	,	PUNCT
admet-2366	164	16	and	and	CCONJ
admet-2366	164	17	corresponding	correspond	VERB
admet-2366	164	18	contour	contour	NOUN
admet-2366	164	19	plots	plot	NOUN
admet-2366	164	20	illustrating	illustrate	VERB
admet-2366	164	21	the	the	DET
admet-2366	164	22	efficiency	efficiency	NOUN
admet-2366	164	23	of	of	ADP
admet-2366	164	24	nanoliposome	nanoliposome	ADJ
admet-2366	164	25	encapsulation	encapsulation	NOUN
admet-2366	164	26	.	.	PUNCT
admet-2366	165	1	quadratic	quadratic	ADJ
admet-2366	165	2	equations	equation	NOUN
admet-2366	165	3	were	be	AUX
admet-2366	165	4	developed	develop	VERB
admet-2366	165	5	to	to	PART
admet-2366	165	6	represent	represent	VERB
admet-2366	165	7	the	the	DET
admet-2366	165	8	relationship	relationship	NOUN
admet-2366	165	9	between	between	ADP
admet-2366	165	10	the	the	DET
admet-2366	165	11	dependent	dependent	ADJ
admet-2366	165	12	and	and	CCONJ
admet-2366	165	13	independent	independent	ADJ
admet-2366	165	14	variables	variable	NOUN
admet-2366	165	15	(	(	PUNCT
admet-2366	165	16	equation	equation	NOUN
admet-2366	165	17	5	5	NUM
admet-2366	165	18	and	and	CCONJ
admet-2366	165	19	6	6	NUM
admet-2366	165	20	)	)	PUNCT
admet-2366	165	21	.	.	PUNCT
admet-2366	166	1	entrapment	entrapment	ADJ
admet-2366	166	2	efficiency	efficiency	NOUN
admet-2366	166	3	=	=	NOUN
admet-2366	166	4	80.43	80.43	NUM
admet-2366	166	5	+	+	CCONJ
admet-2366	166	6	2.52x1	2.52x1	NUM
admet-2366	166	7	–	–	PUNCT
admet-2366	166	8	6.82x2	6.82x2	NUM
admet-2366	167	1	+	+	PUNCT
admet-2366	167	2	3.57x3	3.57x3	NUM
admet-2366	167	3	+	+	CCONJ
admet-2366	167	4	0.3375x1x2	0.3375x1x2	NUM
admet-2366	168	1	+	+	CCONJ
admet-2366	168	2	4.59x1x3	4.59x1x3	NUM
admet-2366	168	3	+	+	PUNCT
admet-2366	169	1	+	+	NUM
admet-2366	169	2	3.75x2x3	3.75x2x3	NUM
admet-2366	169	3	–	–	PUNCT
admet-2366	169	4	20.42x1	20.42x1	NUM
admet-2366	169	5	2	2	NUM
admet-2366	169	6	–	–	PUNCT
admet-2366	169	7	3.50x2	3.50x2	NUM
admet-2366	169	8	2	2	NUM
admet-2366	169	9	–	–	PUNCT
admet-2366	169	10	1.63x3	1.63x3	NUM
admet-2366	169	11	2	2	NUM
admet-2366	169	12	(	(	PUNCT
admet-2366	169	13	5	5	NUM
admet-2366	169	14	)	)	PUNCT
admet-2366	169	15	where	where	SCONJ
admet-2366	169	16	x1	x1	PROPN
admet-2366	169	17	,	,	PUNCT
admet-2366	169	18	x2	x2	PROPN
admet-2366	169	19	,	,	PUNCT
admet-2366	169	20	and	and	CCONJ
admet-2366	169	21	x3	x3	PROPN
admet-2366	169	22	are	be	AUX
admet-2366	169	23	the	the	DET
admet-2366	169	24	main	main	ADJ
admet-2366	169	25	effects	effect	NOUN
admet-2366	169	26	;	;	PUNCT
admet-2366	169	27	x1x2	x1x2	X
admet-2366	169	28	,	,	PUNCT
admet-2366	169	29	x2x3	x2x3	PROPN
admet-2366	169	30	,	,	PUNCT
admet-2366	169	31	and	and	CCONJ
admet-2366	169	32	x1x3	x1x3	PRON
admet-2366	169	33	are	be	AUX
admet-2366	169	34	the	the	DET
admet-2366	169	35	interaction	interaction	NOUN
admet-2366	169	36	terms	term	NOUN
admet-2366	169	37	;	;	PUNCT
admet-2366	169	38	and	and	CCONJ
admet-2366	169	39	x1	x1	DET
admet-2366	169	40	2	2	NUM
admet-2366	169	41	,	,	PUNCT
admet-2366	169	42	x2	x2	NOUN
admet-2366	169	43	2	2	NUM
admet-2366	169	44	,	,	PUNCT
admet-2366	169	45	x3	x3	NOUN
admet-2366	169	46	2	2	NUM
admet-2366	169	47	are	be	AUX
admet-2366	169	48	square	square	ADJ
admet-2366	169	49	terms	term	NOUN
admet-2366	169	50	.	.	PUNCT
admet-2366	170	1	the	the	DET
admet-2366	170	2	percentage	percentage	NOUN
admet-2366	170	3	encapsulation	encapsulation	NOUN
admet-2366	170	4	efficiency	efficiency	NOUN
admet-2366	170	5	's	's	PART
admet-2366	170	6	f	f	NOUN
admet-2366	170	7	-	-	PUNCT
admet-2366	170	8	value	value	NOUN
admet-2366	170	9	(	(	PUNCT
admet-2366	170	10	4.62	4.62	NUM
admet-2366	170	11	)	)	PUNCT
admet-2366	170	12	and	and	CCONJ
admet-2366	170	13	p	p	NOUN
admet-2366	170	14	-	-	PUNCT
admet-2366	170	15	value	value	NOUN
admet-2366	170	16	(	(	PUNCT
admet-2366	170	17	0.0281	0.0281	NUM
admet-2366	170	18	)	)	PUNCT
admet-2366	170	19	indicated	indicate	VERB
admet-2366	170	20	that	that	SCONJ
admet-2366	170	21	the	the	DET
admet-2366	170	22	model	model	NOUN
admet-2366	170	23	is	be	AUX
admet-2366	170	24	significant	significant	ADJ
admet-2366	170	25	.	.	PUNCT
admet-2366	171	1	admet	admet	PROPN
admet-2366	171	2	&	&	CCONJ
admet-2366	171	3	dmpk	dmpk	PROPN
admet-2366	171	4	12(4	12(4	PROPN
admet-2366	171	5	)	)	PUNCT
admet-2366	171	6	(	(	PUNCT
admet-2366	171	7	2024	2024	NUM
admet-2366	171	8	)	)	PUNCT
admet-2366	171	9	657	657	NUM
admet-2366	171	10	-	-	SYM
admet-2366	171	11	677	677	NUM
admet-2366	171	12	optimizing	optimizing	NOUN
admet-2366	171	13	gefitinib	gefitinib	NOUN
admet-2366	171	14	nanoliposomes	nanoliposomes	ADV
admet-2366	171	15	doi	doi	ADV
admet-2366	171	16	:	:	PUNCT
admet-2366	171	17	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	ADJ
admet-2366	171	18	663	663	NUM
admet-2366	171	19	table	table	NOUN
admet-2366	171	20	1	1	NUM
admet-2366	171	21	.	.	PUNCT
admet-2366	172	1	levels	level	NOUN
admet-2366	172	2	of	of	ADP
admet-2366	172	3	independent	independent	ADJ
admet-2366	172	4	parameters	parameter	NOUN
admet-2366	172	5	used	use	VERB
admet-2366	172	6	in	in	ADP
admet-2366	172	7	box	box	NOUN
admet-2366	172	8	-	-	PUNCT
admet-2366	172	9	behnken	behnken	VERB
admet-2366	172	10	design	design	NOUN
admet-2366	172	11	and	and	CCONJ
admet-2366	172	12	results	result	NOUN
admet-2366	172	13	of	of	ADP
admet-2366	172	14	in	in	ADP
admet-2366	172	15	vitro	vitro	X
admet-2366	172	16	characterization	characterization	NOUN
admet-2366	172	17	of	of	ADP
admet-2366	172	18	gefitinib	gefitinib	NOUN
admet-2366	172	19	-	-	PUNCT
admet-2366	172	20	loaded	load	VERB
admet-2366	172	21	nanoliposomes	nanoliposome	NOUN
admet-2366	172	22	.	.	PUNCT
admet-2366	173	1	formulation	formulation	NOUN
admet-2366	173	2	code	code	NOUN
admet-2366	174	1	x1	x1	PROPN
admet-2366	174	2	(	(	PUNCT
admet-2366	174	3	min	min	NOUN
admet-2366	174	4	)	)	PUNCT
admet-2366	174	5	*	*	PUNCT
admet-2366	175	1	x2	x2	PROPN
admet-2366	175	2	*	*	PUNCT
admet-2366	175	3	x3	x3	PROPN
admet-2366	175	4	*	*	PUNCT
admet-2366	175	5	encapsulation	encapsulation	NOUN
admet-2366	175	6	efficiency	efficiency	NOUN
admet-2366	175	7	,	,	PUNCT
admet-2366	175	8	%	%	NOUN
admet-2366	175	9	loading	loading	NOUN
admet-2366	175	10	efficiency	efficiency	NOUN
admet-2366	175	11	,	,	PUNCT
admet-2366	175	12	%	%	NOUN
admet-2366	175	13	particle	particle	NOUN
admet-2366	175	14	size	size	NOUN
admet-2366	175	15	,	,	PUNCT
admet-2366	175	16	nm	nm	ADJ
admet-2366	175	17	pdi	pdi	PROPN
admet-2366	175	18	drug	drug	NOUN
admet-2366	175	19	content	content	NOUN
admet-2366	175	20	,	,	PUNCT
admet-2366	175	21	%	%	INTJ
admet-2366	175	22	zeta	zeta	NOUN
admet-2366	175	23	potential	potential	NOUN
admet-2366	175	24	,	,	PUNCT
admet-2366	175	25	mv	mv	PROPN
admet-2366	175	26	ng1	ng1	NOUN
admet-2366	175	27	-1	-1	PUNCT
admet-2366	175	28	(	(	PUNCT
admet-2366	175	29	5	5	NUM
admet-2366	175	30	)	)	PUNCT
admet-2366	175	31	-1	-1	X
admet-2366	175	32	(	(	PUNCT
admet-2366	175	33	0.6	0.6	NUM
admet-2366	175	34	)	)	PUNCT
admet-2366	175	35	0	0	NUM
admet-2366	176	1	(	(	PUNCT
admet-2366	176	2	0.2	0.2	NUM
admet-2366	176	3	)	)	PUNCT
admet-2366	176	4	66.70±0.14	66.70±0.14	NUM
admet-2366	177	1	31.09±0.21	31.09±0.21	NUM
admet-2366	177	2	195.00	195.00	NUM
admet-2366	177	3	0.288	0.288	NUM
admet-2366	177	4	70.97±0.73	70.97±0.73	NUM
admet-2366	177	5	-8.37	-8.37	NUM
admet-2366	177	6	ng2	ng2	NOUN
admet-2366	177	7	+1	+1	INTJ
admet-2366	177	8	(	(	PUNCT
admet-2366	177	9	15	15	NUM
admet-2366	177	10	)	)	PUNCT
admet-2366	177	11	-1	-1	CCONJ
admet-2366	177	12	(	(	PUNCT
admet-2366	177	13	0.6	0.6	NUM
admet-2366	177	14	)	)	PUNCT
admet-2366	177	15	0	0	NUM
admet-2366	178	1	(	(	PUNCT
admet-2366	178	2	0.2	0.2	NUM
admet-2366	178	3	)	)	PUNCT
admet-2366	178	4	61.20±0.07	61.20±0.07	NUM
admet-2366	178	5	29.81±0.22	29.81±0.22	ADP
admet-2366	178	6	294.80	294.80	NUM
admet-2366	178	7	0.297	0.297	NUM
admet-2366	178	8	64.29±0.42	64.29±0.42	NUM
admet-2366	179	1	-7.98	-7.98	PRON
admet-2366	179	2	ng3	ng3	NOUN
admet-2366	179	3	-1	-1	VERB
admet-2366	179	4	(	(	PUNCT
admet-2366	179	5	5	5	X
admet-2366	179	6	)	)	PUNCT
admet-2366	179	7	+1	+1	NOUN
admet-2366	179	8	(	(	PUNCT
admet-2366	179	9	1.0	1.0	NUM
admet-2366	179	10	)	)	PUNCT
admet-2366	179	11	0	0	NUM
admet-2366	180	1	(	(	PUNCT
admet-2366	180	2	0.2	0.2	NUM
admet-2366	180	3	)	)	PUNCT
admet-2366	180	4	51.15±0.12	51.15±0.12	NUM
admet-2366	180	5	25.58±0.32	25.58±0.32	NUM
admet-2366	180	6	275.60	275.60	NUM
admet-2366	180	7	0.287	0.287	NUM
admet-2366	180	8	54.76±0.62	54.76±0.62	NUM
admet-2366	180	9	-7.43	-7.43	NUM
admet-2366	180	10	ng4	ng4	INTJ
admet-2366	180	11	+1	+1	INTJ
admet-2366	180	12	(	(	PUNCT
admet-2366	180	13	15	15	NUM
admet-2366	180	14	)	)	PUNCT
admet-2366	180	15	+1	+1	NOUN
admet-2366	180	16	(	(	PUNCT
admet-2366	180	17	1.0	1.0	NUM
admet-2366	180	18	)	)	PUNCT
admet-2366	180	19	0	0	NUM
admet-2366	181	1	(	(	PUNCT
admet-2366	181	2	0.2	0.2	NUM
admet-2366	181	3	)	)	PUNCT
admet-2366	181	4	47.00±0.13	47.00±0.13	NUM
admet-2366	181	5	24.50±0.33	24.50±0.33	NUM
admet-2366	181	6	247.80	247.80	NUM
admet-2366	181	7	0.256	0.256	NUM
admet-2366	181	8	50.23±0.38	50.23±0.38	NUM
admet-2366	181	9	-9.75	-9.75	NOUN
admet-2366	181	10	ng5	ng5	PROPN
admet-2366	181	11	-1	-1	PUNCT
admet-2366	181	12	(	(	PUNCT
admet-2366	181	13	5	5	NUM
admet-2366	181	14	)	)	PUNCT
admet-2366	181	15	0	0	NUM
admet-2366	182	1	(	(	PUNCT
admet-2366	182	2	0.8	0.8	NUM
admet-2366	182	3	)	)	PUNCT
admet-2366	182	4	-1	-1	X
admet-2366	183	1	(	(	PUNCT
admet-2366	183	2	0.1	0.1	NUM
admet-2366	183	3	)	)	PUNCT
admet-2366	183	4	50.48±0.13	50.48±0.13	NUM
admet-2366	183	5	24.69±0.24	24.69±0.24	NUM
admet-2366	183	6	160.48	160.48	NUM
admet-2366	183	7	0.376	0.376	NUM
admet-2366	183	8	53.76±0.44	53.76±0.44	NUM
admet-2366	183	9	-9.12	-9.12	NUM
admet-2366	183	10	ng6	ng6	NOUN
admet-2366	183	11	+1	+1	PROPN
admet-2366	183	12	(	(	PUNCT
admet-2366	183	13	15	15	NUM
admet-2366	183	14	)	)	PUNCT
admet-2366	183	15	0	0	NUM
admet-2366	183	16	(	(	PUNCT
admet-2366	183	17	0.8	0.8	NUM
admet-2366	183	18	)	)	PUNCT
admet-2366	183	19	-1	-1	X
admet-2366	183	20	(	(	PUNCT
admet-2366	183	21	0.1	0.1	NUM
admet-2366	183	22	)	)	PUNCT
admet-2366	183	23	56.20±0.15	56.20±0.15	NUM
admet-2366	183	24	28.95±0.21	28.95±0.21	NUM
admet-2366	183	25	380.48	380.48	NUM
admet-2366	183	26	0.425	0.425	NUM
admet-2366	183	27	59.96±0.51	59.96±0.51	NUM
admet-2366	183	28	-7.72	-7.72	NOUN
admet-2366	183	29	ng7	ng7	NOUN
admet-2366	183	30	-1	-1	PROPN
admet-2366	183	31	(	(	PUNCT
admet-2366	183	32	5	5	NUM
admet-2366	183	33	)	)	PUNCT
admet-2366	183	34	0	0	NUM
admet-2366	184	1	(	(	PUNCT
admet-2366	184	2	0.8	0.8	NUM
admet-2366	184	3	)	)	PUNCT
admet-2366	184	4	+1	+1	NOUN
admet-2366	184	5	(	(	PUNCT
admet-2366	184	6	0.3	0.3	NUM
admet-2366	184	7	)	)	PUNCT
admet-2366	185	1	51.37±0.17	51.37±0.17	NUM
admet-2366	185	2	26.67±0.16	26.67±0.16	NUM
admet-2366	186	1	351.37	351.37	NUM
admet-2366	186	2	0.427	0.427	NUM
admet-2366	186	3	54.28±0.78	54.28±0.78	NUM
admet-2366	186	4	-7.34	-7.34	ADJ
admet-2366	186	5	ng8	ng8	NOUN
admet-2366	186	6	+1	+1	PROPN
admet-2366	186	7	(	(	PUNCT
admet-2366	186	8	15	15	NUM
admet-2366	186	9	)	)	PUNCT
admet-2366	186	10	0	0	NUM
admet-2366	186	11	(	(	PUNCT
admet-2366	186	12	0.8	0.8	NUM
admet-2366	186	13	)	)	PUNCT
admet-2366	186	14	+1	+1	NOUN
admet-2366	186	15	(	(	PUNCT
admet-2366	186	16	0.3	0.3	NUM
admet-2366	186	17	)	)	PUNCT
admet-2366	186	18	75.46±0.11	75.46±0.11	NUM
admet-2366	186	19	32.23±0.17	32.23±0.17	NUM
admet-2366	186	20	278.96	278.96	NUM
admet-2366	186	21	0.428	0.428	NUM
admet-2366	186	22	78.54±0.87	78.54±0.87	NUM
admet-2366	186	23	-6.97	-6.97	VERB
admet-2366	186	24	ng9	ng9	NUM
admet-2366	186	25	0	0	NUM
admet-2366	186	26	(	(	PUNCT
admet-2366	186	27	10	10	NUM
admet-2366	186	28	)	)	PUNCT
admet-2366	186	29	+1	+1	NOUN
admet-2366	186	30	(	(	PUNCT
admet-2366	186	31	1.0	1.0	NUM
admet-2366	186	32	)	)	PUNCT
admet-2366	186	33	+1	+1	NOUN
admet-2366	186	34	(	(	PUNCT
admet-2366	186	35	0.3	0.3	NUM
admet-2366	186	36	)	)	PUNCT
admet-2366	187	1	83.14±0.13	83.14±0.13	PROPN
admet-2366	187	2	34.36±0.15	34.36±0.15	NUM
admet-2366	187	3	383.14	383.14	NUM
admet-2366	187	4	0.422	0.422	NUM
admet-2366	187	5	85.67±0.95	85.67±0.95	NUM
admet-2366	187	6	-6.78	-6.78	VERB
admet-2366	187	7	ng10	ng10	PROPN
admet-2366	187	8	0	0	NUM
admet-2366	187	9	(	(	PUNCT
admet-2366	187	10	10	10	NUM
admet-2366	187	11	)	)	PUNCT
admet-2366	187	12	+1	+1	NOUN
admet-2366	187	13	(	(	PUNCT
admet-2366	187	14	1.0	1.0	NUM
admet-2366	187	15	)	)	PUNCT
admet-2366	187	16	-1	-1	X
admet-2366	187	17	(	(	PUNCT
admet-2366	187	18	0.1	0.1	NUM
admet-2366	187	19	)	)	PUNCT
admet-2366	187	20	63.25±0.10	63.25±0.10	NUM
admet-2366	187	21	30.90±0.14	30.90±0.14	NUM
admet-2366	187	22	363.25	363.25	NUM
admet-2366	187	23	0.422	0.422	NUM
admet-2366	187	24	67.49±0.54	67.49±0.54	NUM
admet-2366	187	25	-7.65	-7.65	PRON
admet-2366	187	26	ng11	ng11	PROPN
admet-2366	187	27	0	0	NUM
admet-2366	187	28	(	(	PUNCT
admet-2366	187	29	10	10	NUM
admet-2366	187	30	)	)	PUNCT
admet-2366	187	31	-1	-1	CCONJ
admet-2366	187	32	(	(	PUNCT
admet-2366	187	33	0.6	0.6	X
admet-2366	187	34	)	)	PUNCT
admet-2366	187	35	+1	+1	NOUN
admet-2366	187	36	(	(	PUNCT
admet-2366	187	37	0.3	0.3	NUM
admet-2366	187	38	)	)	PUNCT
admet-2366	187	39	79.85±0.12	79.85±0.12	PROPN
admet-2366	188	1	33.13±0.18	33.13±0.18	NUM
admet-2366	189	1	296.50	296.50	NUM
admet-2366	189	2	0.410	0.410	NUM
admet-2366	189	3	81.76±0.78	81.76±0.78	NUM
admet-2366	189	4	-7.32	-7.32	NUM
admet-2366	189	5	ng12	ng12	PROPN
admet-2366	189	6	0	0	NUM
admet-2366	189	7	(	(	PUNCT
admet-2366	189	8	10	10	NUM
admet-2366	189	9	)	)	PUNCT
admet-2366	189	10	-1	-1	CCONJ
admet-2366	189	11	(	(	PUNCT
admet-2366	189	12	0.6	0.6	NUM
admet-2366	189	13	)	)	PUNCT
admet-2366	189	14	-1	-1	X
admet-2366	189	15	(	(	PUNCT
admet-2366	189	16	0.1	0.1	NUM
admet-2366	189	17	)	)	PUNCT
admet-2366	189	18	74.96±0.15	74.96±0.15	NOUN
admet-2366	189	19	31.73±0.32	31.73±0.32	NUM
admet-2366	189	20	186.70	186.70	NUM
admet-2366	189	21	0.242	0.242	NUM
admet-2366	189	22	77.43±0.42	77.43±0.42	NUM
admet-2366	189	23	-7.02	-7.02	PROPN
admet-2366	189	24	ng13	ng13	PROPN
admet-2366	189	25	0	0	NUM
admet-2366	189	26	(	(	PUNCT
admet-2366	189	27	10	10	NUM
admet-2366	189	28	)	)	PUNCT
admet-2366	189	29	0	0	NUM
admet-2366	189	30	(	(	PUNCT
admet-2366	189	31	0.8	0.8	NUM
admet-2366	189	32	)	)	PUNCT
admet-2366	189	33	0	0	NUM
admet-2366	189	34	(	(	PUNCT
admet-2366	189	35	0.2	0.2	NUM
admet-2366	189	36	)	)	PUNCT
admet-2366	189	37	87.56±0.17	87.56±0.17	NUM
admet-2366	189	38	35.16±0.31	35.16±0.31	NUM
admet-2366	189	39	93.20	93.20	NUM
admet-2366	189	40	0.233	0.233	NUM
admet-2366	189	41	89.76±0.51	89.76±0.51	NUM
admet-2366	189	42	-6.46	-6.46	NUM
admet-2366	189	43	ng14	ng14	PROPN
admet-2366	189	44	0	0	NUM
admet-2366	189	45	(	(	PUNCT
admet-2366	189	46	10	10	NUM
admet-2366	189	47	)	)	PUNCT
admet-2366	189	48	0	0	NUM
admet-2366	189	49	(	(	PUNCT
admet-2366	189	50	0.8	0.8	NUM
admet-2366	189	51	)	)	PUNCT
admet-2366	189	52	0	0	NUM
admet-2366	189	53	(	(	PUNCT
admet-2366	189	54	0.2	0.2	NUM
admet-2366	189	55	)	)	PUNCT
admet-2366	189	56	85.96±0.15	85.96±0.15	NUM
admet-2366	189	57	34.89±0.33	34.89±0.33	NUM
admet-2366	189	58	179.60	179.60	NUM
admet-2366	189	59	0.236	0.236	NUM
admet-2366	189	60	88.56±0.63	88.56±0.63	NUM
admet-2366	189	61	-6.76	-6.76	PUNCT
admet-2366	189	62	ng15	ng15	PROPN
admet-2366	189	63	0	0	NUM
admet-2366	189	64	(	(	PUNCT
admet-2366	189	65	10	10	NUM
admet-2366	189	66	)	)	PUNCT
admet-2366	189	67	0	0	NUM
admet-2366	189	68	(	(	PUNCT
admet-2366	189	69	0.8	0.8	NUM
admet-2366	189	70	)	)	PUNCT
admet-2366	189	71	0	0	NUM
admet-2366	189	72	(	(	PUNCT
admet-2366	189	73	0.2	0.2	NUM
admet-2366	189	74	)	)	PUNCT
admet-2366	189	75	74.46±0.14	74.46±0.14	NUM
admet-2366	189	76	33.62±0.31	33.62±0.31	NUM
admet-2366	190	1	160.90	160.90	NUM
admet-2366	190	2	0.245	0.245	NUM
admet-2366	190	3	87.32±0.51	87.32±0.51	NUM
admet-2366	190	4	-6.67	-6.67	NOUN
admet-2366	190	5	ng16	ng16	PROPN
admet-2366	190	6	0	0	NUM
admet-2366	190	7	(	(	PUNCT
admet-2366	190	8	10	10	NUM
admet-2366	190	9	)	)	PUNCT
admet-2366	190	10	0	0	NUM
admet-2366	190	11	(	(	PUNCT
admet-2366	190	12	0.8	0.8	NUM
admet-2366	190	13	)	)	PUNCT
admet-2366	190	14	0	0	NUM
admet-2366	190	15	(	(	PUNCT
admet-2366	190	16	0.2	0.2	NUM
admet-2366	190	17	)	)	PUNCT
admet-2366	190	18	70.97±0.18	70.97±0.18	NUM
admet-2366	190	19	31.89±0.34	31.89±0.34	NUM
admet-2366	190	20	101.60	101.60	NUM
admet-2366	190	21	0.235	0.235	NUM
admet-2366	190	22	79.56±0.64	79.56±0.64	PROPN
admet-2366	190	23	-6.47	-6.47	NOUN
admet-2366	190	24	ng17	ng17	PROPN
admet-2366	190	25	0	0	NUM
admet-2366	190	26	(	(	PUNCT
admet-2366	190	27	10	10	NUM
admet-2366	190	28	)	)	PUNCT
admet-2366	190	29	0	0	NUM
admet-2366	190	30	(	(	PUNCT
admet-2366	190	31	0.8	0.8	NUM
admet-2366	190	32	)	)	PUNCT
admet-2366	190	33	0	0	NUM
admet-2366	190	34	(	(	PUNCT
admet-2366	190	35	0.2	0.2	NUM
admet-2366	190	36	)	)	PUNCT
admet-2366	190	37	83.18±0.16	83.18±0.16	PROPN
admet-2366	190	38	34.91±0.32	34.91±0.32	NUM
admet-2366	190	39	101.90	101.90	NUM
admet-2366	190	40	0.237	0.237	NUM
admet-2366	190	41	81.57±0.72	81.57±0.72	NUM
admet-2366	190	42	-6.48	-6.48	NOUN
admet-2366	190	43	*	*	PUNCT
admet-2366	190	44	actual	actual	ADJ
admet-2366	190	45	values	value	NOUN
admet-2366	190	46	are	be	AUX
admet-2366	190	47	given	give	VERB
admet-2366	190	48	in	in	ADP
admet-2366	190	49	brackets	bracket	NOUN
admet-2366	190	50	particle	particle	NOUN
admet-2366	190	51	size	size	NOUN
admet-2366	190	52	,	,	PUNCT
admet-2366	190	53	polydispersity	polydispersity	NOUN
admet-2366	190	54	index	index	NOUN
admet-2366	190	55	and	and	CCONJ
admet-2366	190	56	zeta	zeta	NOUN
admet-2366	190	57	potential	potential	NOUN
admet-2366	190	58	the	the	DET
admet-2366	190	59	particle	particle	NOUN
admet-2366	190	60	size	size	NOUN
admet-2366	190	61	ranged	range	VERB
admet-2366	190	62	between	between	ADP
admet-2366	190	63	93.2	93.2	NUM
admet-2366	190	64	and	and	CCONJ
admet-2366	190	65	490.0	490.0	NUM
admet-2366	190	66	nm	nm	NOUN
admet-2366	190	67	,	,	PUNCT
admet-2366	190	68	whereas	whereas	SCONJ
admet-2366	190	69	the	the	DET
admet-2366	190	70	polydispersity	polydispersity	NOUN
admet-2366	190	71	index	index	NOUN
admet-2366	190	72	values	value	NOUN
admet-2366	190	73	varied	varied	ADJ
admet-2366	190	74	from	from	ADP
admet-2366	190	75	0.233	0.233	NUM
admet-2366	190	76	to	to	ADP
admet-2366	190	77	0.428	0.428	NUM
admet-2366	190	78	for	for	ADP
admet-2366	190	79	all	all	DET
admet-2366	190	80	formulations	formulation	NOUN
admet-2366	190	81	.	.	PUNCT
admet-2366	191	1	batch	batch	NOUN
admet-2366	191	2	ng13	ng13	PROPN
admet-2366	191	3	had	have	VERB
admet-2366	191	4	a	a	DET
admet-2366	191	5	minimum	minimum	ADJ
admet-2366	191	6	particle	particle	NOUN
admet-2366	191	7	size	size	NOUN
admet-2366	191	8	of	of	ADP
admet-2366	191	9	93.2	93.2	NUM
admet-2366	191	10	nm	nm	NOUN
admet-2366	191	11	with	with	ADP
admet-2366	191	12	a	a	DET
admet-2366	191	13	pdi	pdi	NOUN
admet-2366	191	14	of	of	ADP
admet-2366	191	15	0.233	0.233	NUM
admet-2366	191	16	(	(	PUNCT
admet-2366	191	17	table	table	NOUN
admet-2366	191	18	1	1	NUM
admet-2366	191	19	)	)	PUNCT
admet-2366	191	20	.	.	PUNCT
admet-2366	192	1	the	the	DET
admet-2366	192	2	zeta	zeta	PROPN
admet-2366	192	3	potential	potential	NOUN
admet-2366	192	4	of	of	ADP
admet-2366	192	5	the	the	DET
admet-2366	192	6	optimized	optimize	VERB
admet-2366	192	7	batch	batch	NOUN
admet-2366	192	8	was	be	AUX
admet-2366	192	9	found	find	VERB
admet-2366	192	10	to	to	PART
admet-2366	192	11	be	be	AUX
admet-2366	192	12	6.51±0.03	6.51±0.03	ADJ
admet-2366	192	13	mv	mv	NOUN
admet-2366	192	14	.	.	PUNCT
admet-2366	193	1	however	however	ADV
admet-2366	193	2	,	,	PUNCT
admet-2366	193	3	after	after	ADP
admet-2366	193	4	coating	coat	VERB
admet-2366	193	5	,	,	PUNCT
admet-2366	193	6	the	the	DET
admet-2366	193	7	value	value	NOUN
admet-2366	193	8	of	of	ADP
admet-2366	193	9	zeta	zeta	PROPN
admet-2366	193	10	potential	potential	NOUN
admet-2366	193	11	was	be	AUX
admet-2366	193	12	found	find	VERB
admet-2366	193	13	to	to	PART
admet-2366	193	14	be	be	AUX
admet-2366	193	15	23.7±0.03	23.7±0.03	NUM
admet-2366	193	16	mv	mv	NOUN
admet-2366	193	17	.	.	PUNCT
admet-2366	194	1	a	a	DET
admet-2366	194	2	pareto	pareto	ADJ
admet-2366	194	3	chart	chart	NOUN
admet-2366	194	4	was	be	AUX
admet-2366	194	5	prepared	prepared	ADJ
admet-2366	194	6	to	to	PART
admet-2366	194	7	analyse	analyse	VERB
admet-2366	194	8	the	the	DET
admet-2366	194	9	effect	effect	NOUN
admet-2366	194	10	of	of	ADP
admet-2366	194	11	coefficients	coefficient	NOUN
admet-2366	194	12	on	on	ADP
admet-2366	194	13	particle	particle	NOUN
admet-2366	194	14	size	size	NOUN
admet-2366	194	15	(	(	PUNCT
admet-2366	194	16	figure	figure	NOUN
admet-2366	194	17	1	1	NUM
admet-2366	194	18	)	)	PUNCT
admet-2366	194	19	.	.	PUNCT
admet-2366	195	1	the	the	DET
admet-2366	195	2	3d	3d	PROPN
admet-2366	195	3	response	response	NOUN
admet-2366	195	4	surface	surface	NOUN
admet-2366	195	5	plots	plot	NOUN
admet-2366	195	6	are	be	AUX
admet-2366	195	7	depicted	depict	VERB
admet-2366	195	8	in	in	ADP
admet-2366	195	9	figure	figure	NOUN
admet-2366	195	10	2	2	NUM
admet-2366	195	11	.	.	PUNCT
admet-2366	196	1	the	the	DET
admet-2366	196	2	polynomial	polynomial	ADJ
admet-2366	196	3	equation	equation	NOUN
admet-2366	196	4	was	be	AUX
admet-2366	196	5	generated	generate	VERB
admet-2366	196	6	using	use	VERB
admet-2366	196	7	design	design	NOUN
admet-2366	196	8	expert	expert	NOUN
admet-2366	196	9	®	®	NOUN
admet-2366	196	10	software	software	NOUN
admet-2366	196	11	.	.	PUNCT
admet-2366	197	1	the	the	DET
admet-2366	197	2	particle	particle	NOUN
admet-2366	197	3	size	size	NOUN
admet-2366	197	4	f	f	NOUN
admet-2366	197	5	-	-	PUNCT
admet-2366	197	6	value	value	NOUN
admet-2366	197	7	(	(	PUNCT
admet-2366	197	8	3.95	3.95	NUM
admet-2366	197	9	)	)	PUNCT
admet-2366	197	10	and	and	CCONJ
admet-2366	197	11	pvalue	pvalue	NOUN
admet-2366	197	12	(	(	PUNCT
admet-2366	197	13	0.0418	0.0418	NUM
admet-2366	197	14	)	)	PUNCT
admet-2366	197	15	indicated	indicate	VERB
admet-2366	197	16	that	that	SCONJ
admet-2366	197	17	the	the	DET
admet-2366	197	18	model	model	NOUN
admet-2366	197	19	is	be	AUX
admet-2366	197	20	significant	significant	ADJ
admet-2366	197	21	.	.	PUNCT
admet-2366	198	1	an	an	DET
admet-2366	198	2	excellent	excellent	ADJ
admet-2366	198	3	agreement	agreement	NOUN
admet-2366	198	4	was	be	AUX
admet-2366	198	5	found	find	VERB
admet-2366	198	6	between	between	ADP
admet-2366	198	7	the	the	DET
admet-2366	198	8	actual	actual	ADJ
admet-2366	198	9	value	value	NOUN
admet-2366	198	10	and	and	CCONJ
admet-2366	198	11	the	the	DET
admet-2366	198	12	predicted	predict	VERB
admet-2366	198	13	value	value	NOUN
admet-2366	198	14	,	,	PUNCT
admet-2366	198	15	which	which	PRON
admet-2366	198	16	indicates	indicate	VERB
admet-2366	198	17	the	the	DET
admet-2366	198	18	validity	validity	NOUN
admet-2366	198	19	of	of	ADP
admet-2366	198	20	the	the	DET
admet-2366	198	21	developed	develop	VERB
admet-2366	198	22	model	model	NOUN
admet-2366	198	23	(	(	PUNCT
admet-2366	198	24	table	table	NOUN
admet-2366	198	25	2	2	NUM
admet-2366	198	26	)	)	PUNCT
admet-2366	198	27	.	.	PUNCT
admet-2366	199	1	particle	particle	NOUN
admet-2366	199	2	size	size	NOUN
admet-2366	199	3	=	=	NOUN
admet-2366	199	4	127.44	127.44	NUM
admet-2366	199	5	+	+	NUM
admet-2366	199	6	27.45x1	27.45x1	NUM
admet-2366	199	7	12.01x2	12.01x2	NUM
admet-2366	199	8	21.73x3	21.73x3	NUM
admet-2366	199	9	31.90	31.90	NUM
admet-2366	199	10	x1x2	x1x2	X
admet-2366	199	11	73.10	73.10	NUM
admet-2366	199	12	x1x3	x1x3	X
admet-2366	199	13	22.48	22.48	NUM
admet-2366	199	14	x2x3	x2x3	PUNCT
admet-2366	200	1	+	+	NUM
admet-2366	200	2	55.64	55.64	NUM
admet-2366	200	3	x1	x1	NOUN
admet-2366	200	4	2	2	NUM
admet-2366	200	5	+	+	SYM
admet-2366	200	6	70.22	70.22	NUM
admet-2366	200	7	x2	x2	SYM
admet-2366	200	8	2	2	NUM
admet-2366	200	9	+	+	NUM
admet-2366	200	10	109.74	109.74	NUM
admet-2366	200	11	x3	x3	ADJ
admet-2366	200	12	2	2	NUM
admet-2366	200	13	(	(	PUNCT
admet-2366	200	14	6	6	NUM
admet-2366	200	15	)	)	PUNCT
admet-2366	200	16	figure	figure	NOUN
admet-2366	200	17	1	1	NUM
admet-2366	200	18	.	.	PUNCT
admet-2366	200	19	(	(	PUNCT
admet-2366	200	20	i	i	NOUN
admet-2366	200	21	)	)	PUNCT
admet-2366	200	22	upshot	upshot	ADJ
admet-2366	200	23	plot	plot	NOUN
admet-2366	200	24	of	of	ADP
admet-2366	200	25	coefficients	coefficient	NOUN
admet-2366	200	26	on	on	ADP
admet-2366	200	27	encapsulation	encapsulation	NOUN
admet-2366	200	28	efficiency	efficiency	NOUN
admet-2366	200	29	[	[	X
admet-2366	200	30	a1	a1	NOUN
admet-2366	200	31	,	,	PUNCT
admet-2366	200	32	a2	a2	PROPN
admet-2366	200	33	,	,	PUNCT
admet-2366	200	34	and	and	CCONJ
admet-2366	200	35	a3	a3	NOUN
admet-2366	200	36	are	be	AUX
admet-2366	200	37	coefficients	coefficient	NOUN
admet-2366	200	38	of	of	ADP
admet-2366	200	39	main	main	ADJ
admet-2366	200	40	effects	effect	NOUN
admet-2366	200	41	(	(	PUNCT
admet-2366	200	42	x1	x1	PROPN
admet-2366	200	43	,	,	PUNCT
admet-2366	200	44	x2	x2	PROPN
admet-2366	200	45	,	,	PUNCT
admet-2366	200	46	and	and	CCONJ
admet-2366	200	47	x3	x3	ADJ
admet-2366	200	48	)	)	PUNCT
admet-2366	200	49	;	;	PUNCT
admet-2366	200	50	a4	a4	NOUN
admet-2366	200	51	,	,	PUNCT
admet-2366	200	52	a5	a5	NOUN
admet-2366	200	53	,	,	PUNCT
admet-2366	200	54	and	and	CCONJ
admet-2366	200	55	a6	a6	NOUN
admet-2366	200	56	are	be	AUX
admet-2366	200	57	coefficients	coefficient	NOUN
admet-2366	200	58	of	of	ADP
admet-2366	200	59	interaction	interaction	NOUN
admet-2366	200	60	terms	term	NOUN
admet-2366	200	61	(	(	PUNCT
admet-2366	200	62	x1x2	x1x2	X
admet-2366	200	63	,	,	PUNCT
admet-2366	200	64	x2x3	x2x3	PROPN
admet-2366	200	65	,	,	PUNCT
admet-2366	200	66	and	and	CCONJ
admet-2366	200	67	x1x3	x1x3	X
admet-2366	200	68	)	)	PUNCT
admet-2366	200	69	;	;	PUNCT
admet-2366	200	70	and	and	CCONJ
admet-2366	200	71	a7	a7	PROPN
admet-2366	200	72	,	,	PUNCT
admet-2366	200	73	a8	a8	PROPN
admet-2366	200	74	,	,	PUNCT
admet-2366	200	75	and	and	CCONJ
admet-2366	200	76	a9	a9	NOUN
admet-2366	200	77	are	be	AUX
admet-2366	200	78	coefficients	coefficient	NOUN
admet-2366	200	79	of	of	ADP
admet-2366	200	80	square	square	ADJ
admet-2366	200	81	terms	term	NOUN
admet-2366	200	82	(	(	PUNCT
admet-2366	200	83	x1	x1	PROPN
admet-2366	200	84	2	2	NUM
admet-2366	200	85	,	,	PUNCT
admet-2366	200	86	x2	x2	NOUN
admet-2366	200	87	2	2	NUM
admet-2366	200	88	,	,	PUNCT
admet-2366	200	89	x3	x3	NOUN
admet-2366	200	90	2	2	NUM
admet-2366	200	91	)	)	PUNCT
admet-2366	200	92	]	]	PUNCT
admet-2366	200	93	.	.	PUNCT
admet-2366	201	1	(	(	PUNCT
admet-2366	201	2	ii	ii	NOUN
admet-2366	201	3	)	)	PUNCT
admet-2366	201	4	upshot	upshot	ADJ
admet-2366	201	5	plot	plot	NOUN
admet-2366	201	6	of	of	ADP
admet-2366	201	7	particle	particle	NOUN
admet-2366	201	8	size	size	NOUN
admet-2366	201	9	[	[	X
admet-2366	201	10	(	(	PUNCT
admet-2366	201	11	b1	b1	NOUN
admet-2366	201	12	,	,	PUNCT
admet-2366	201	13	b2	b2	NOUN
admet-2366	201	14	,	,	PUNCT
admet-2366	201	15	and	and	CCONJ
admet-2366	201	16	b3	b3	PROPN
admet-2366	201	17	are	be	AUX
admet-2366	201	18	coefficients	coefficient	NOUN
admet-2366	201	19	of	of	ADP
admet-2366	201	20	main	main	ADJ
admet-2366	201	21	effects	effect	NOUN
admet-2366	201	22	(	(	PUNCT
admet-2366	201	23	x1	x1	PROPN
admet-2366	201	24	,	,	PUNCT
admet-2366	201	25	x2	x2	PROPN
admet-2366	201	26	,	,	PUNCT
admet-2366	201	27	and	and	CCONJ
admet-2366	201	28	x3	x3	ADJ
admet-2366	201	29	)	)	PUNCT
admet-2366	201	30	;	;	PUNCT
admet-2366	201	31	b4	b4	NOUN
admet-2366	201	32	,	,	PUNCT
admet-2366	201	33	b5	b5	PROPN
admet-2366	201	34	,	,	PUNCT
admet-2366	201	35	and	and	CCONJ
admet-2366	201	36	b6	b6	NOUN
admet-2366	201	37	are	be	AUX
admet-2366	201	38	coefficients	coefficient	NOUN
admet-2366	201	39	of	of	ADP
admet-2366	201	40	interaction	interaction	NOUN
admet-2366	201	41	terms	term	NOUN
admet-2366	201	42	(	(	PUNCT
admet-2366	201	43	x1x2	x1x2	X
admet-2366	201	44	,	,	PUNCT
admet-2366	201	45	x2x3	x2x3	PROPN
admet-2366	201	46	,	,	PUNCT
admet-2366	201	47	and	and	CCONJ
admet-2366	201	48	x1x3	x1x3	X
admet-2366	201	49	)	)	PUNCT
admet-2366	201	50	;	;	PUNCT
admet-2366	201	51	and	and	CCONJ
admet-2366	201	52	b7	b7	PROPN
admet-2366	201	53	,	,	PUNCT
admet-2366	201	54	b8	b8	PROPN
admet-2366	201	55	,	,	PUNCT
admet-2366	201	56	and	and	CCONJ
admet-2366	201	57	b9	b9	PROPN
admet-2366	201	58	are	be	AUX
admet-2366	201	59	coefficients	coefficient	NOUN
admet-2366	201	60	of	of	ADP
admet-2366	201	61	square	square	ADJ
admet-2366	201	62	terms	term	NOUN
admet-2366	201	63	(	(	PUNCT
admet-2366	201	64	x1	x1	PROPN
admet-2366	201	65	2	2	NUM
admet-2366	201	66	,	,	PUNCT
admet-2366	201	67	x2	x2	NOUN
admet-2366	201	68	2	2	NUM
admet-2366	201	69	,	,	PUNCT
admet-2366	201	70	x3	x3	NOUN
admet-2366	201	71	2	2	NUM
admet-2366	201	72	)	)	PUNCT
admet-2366	201	73	]	]	PUNCT
admet-2366	201	74	.	.	PUNCT
admet-2366	202	1	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PROPN
admet-2366	202	2	s.	s.	PROPN
admet-2366	202	3	rohilla	rohilla	PROPN
admet-2366	202	4	et	et	PROPN
admet-2366	202	5	al	al	PROPN
admet-2366	202	6	.	.	PROPN
admet-2366	202	7	admet	admet	PROPN
admet-2366	202	8	&	&	CCONJ
admet-2366	202	9	dmpk	dmpk	PROPN
admet-2366	202	10	12(4	12(4	PROPN
admet-2366	202	11	)	)	PUNCT
admet-2366	202	12	(	(	PUNCT
admet-2366	202	13	2024	2024	NUM
admet-2366	202	14	)	)	PUNCT
admet-2366	202	15	657	657	NUM
admet-2366	202	16	-	-	SYM
admet-2366	202	17	677	677	NUM
admet-2366	202	18	664	664	NUM
admet-2366	202	19	figure	figure	NOUN
admet-2366	202	20	2	2	NUM
admet-2366	202	21	.	.	PUNCT
admet-2366	202	22	response	response	NOUN
admet-2366	202	23	surface	surface	NOUN
admet-2366	202	24	plots	plot	NOUN
admet-2366	202	25	and	and	CCONJ
admet-2366	202	26	contour	contour	NOUN
admet-2366	202	27	plots	plot	NOUN
admet-2366	202	28	showing	show	VERB
admet-2366	202	29	the	the	DET
admet-2366	202	30	influence	influence	NOUN
admet-2366	202	31	of	of	ADP
admet-2366	202	32	level	level	NOUN
admet-2366	202	33	of	of	ADP
admet-2366	202	34	sonication	sonication	NOUN
admet-2366	202	35	time	time	NOUN
admet-2366	202	36	,	,	PUNCT
admet-2366	202	37	tween	tween	NOUN
admet-2366	202	38	80	80	NUM
admet-2366	202	39	/	/	SYM
admet-2366	202	40	soya	soya	NOUN
admet-2366	202	41	lecithin	lecithin	NOUN
admet-2366	202	42	ratio	ratio	NOUN
admet-2366	202	43	,	,	PUNCT
admet-2366	202	44	and	and	CCONJ
admet-2366	202	45	cholesterol	cholesterol	NOUN
admet-2366	202	46	/	/	SYM
admet-2366	202	47	soya	soya	NOUN
admet-2366	202	48	lecithin	lecithin	NOUN
admet-2366	202	49	ratio	ratio	NOUN
admet-2366	202	50	on	on	ADP
admet-2366	202	51	mean	mean	ADJ
admet-2366	202	52	particle	particle	NOUN
admet-2366	202	53	size	size	NOUN
admet-2366	202	54	(	(	PUNCT
admet-2366	202	55	i	i	PROPN
admet-2366	202	56	,	,	PUNCT
admet-2366	202	57	ii	ii	PROPN
admet-2366	202	58	)	)	PUNCT
admet-2366	202	59	and	and	CCONJ
admet-2366	202	60	encapsulation	encapsulation	NOUN
admet-2366	202	61	efficiency	efficiency	NOUN
admet-2366	202	62	(	(	PUNCT
admet-2366	202	63	iii	iii	NOUN
admet-2366	202	64	,	,	PUNCT
admet-2366	202	65	iv	iv	NUM
admet-2366	202	66	)	)	PUNCT
admet-2366	202	67	.	.	PUNCT
admet-2366	203	1	table	table	NOUN
admet-2366	203	2	2	2	NUM
admet-2366	203	3	.	.	PUNCT
admet-2366	203	4	actual	actual	ADJ
admet-2366	203	5	and	and	CCONJ
admet-2366	203	6	predicted	predict	VERB
admet-2366	203	7	values	value	NOUN
admet-2366	203	8	for	for	ADP
admet-2366	203	9	all	all	DET
admet-2366	203	10	response	response	NOUN
admet-2366	203	11	variables	variable	NOUN
admet-2366	203	12	for	for	ADP
admet-2366	203	13	different	different	ADJ
admet-2366	203	14	batches	batch	NOUN
admet-2366	203	15	.	.	PUNCT
admet-2366	204	1	formulation	formulation	NOUN
admet-2366	204	2	code	code	NOUN
admet-2366	204	3	mean	mean	NOUN
admet-2366	204	4	particle	particle	NOUN
admet-2366	204	5	size	size	NOUN
admet-2366	204	6	,	,	PUNCT
admet-2366	204	7	nm	nm	PRON
admet-2366	204	8	encapsulation	encapsulation	NOUN
admet-2366	204	9	efficiency	efficiency	NOUN
admet-2366	204	10	,	,	PUNCT
admet-2366	204	11	%	%	NOUN
admet-2366	204	12	cumulative	cumulative	ADJ
admet-2366	204	13	drug	drug	NOUN
admet-2366	204	14	release	release	NOUN
admet-2366	204	15	,	,	PUNCT
admet-2366	204	16	%	%	NOUN
admet-2366	204	17	actual	actual	ADJ
admet-2366	204	18	predicted	predict	VERB
admet-2366	204	19	actual	actual	ADJ
admet-2366	204	20	predicted	predict	VERB
admet-2366	204	21	actual	actual	ADJ
admet-2366	204	22	predicted	predict	VERB
admet-2366	204	23	ng1	ng1	NOUN
admet-2366	204	24	179.60	179.60	NUM
admet-2366	204	25	127.44	127.44	NUM
admet-2366	204	26	85.96	85.96	NUM
admet-2366	204	27	80.43	80.43	NUM
admet-2366	204	28	81.96	81.96	NUM
admet-2366	204	29	79.72	79.72	NUM
admet-2366	204	30	ng2	ng2	NOUN
admet-2366	204	31	195.00	195.00	NUM
admet-2366	204	32	217.20	217.20	NUM
admet-2366	204	33	66.70	66.70	NUM
admet-2366	204	34	61.15	61.15	NUM
admet-2366	204	35	68.88	68.88	NUM
admet-2366	204	36	68.83	68.83	NUM
admet-2366	204	37	ng3	ng3	NOUN
admet-2366	204	38	101.60	101.60	NUM
admet-2366	204	39	127.44	127.44	NUM
admet-2366	204	40	70.97	70.97	NUM
admet-2366	204	41	80.43	80.43	NUM
admet-2366	204	42	75.69	75.69	NUM
admet-2366	204	43	79.72	79.72	NUM
admet-2366	204	44	ng4	ng4	NOUN
admet-2366	204	45	93.20	93.20	NUM
admet-2366	204	46	127.44	127.44	NUM
admet-2366	204	47	87.56	87.56	NUM
admet-2366	204	48	80.43	80.43	NUM
admet-2366	204	49	82.16	82.16	NUM
admet-2366	204	50	79.72	79.72	NUM
admet-2366	204	51	ng5	ng5	NOUN
admet-2366	204	52	351.37	351.37	NUM
admet-2366	204	53	318.29	318.29	NUM
admet-2366	204	54	51.37	51.37	NUM
admet-2366	204	55	54.84	54.84	NUM
admet-2366	204	56	76.90	76.90	NUM
admet-2366	204	57	76.82	76.82	NUM
admet-2366	204	58	ng6	ng6	NOUN
admet-2366	204	59	101.90	101.90	NUM
admet-2366	204	60	127.44	127.44	NUM
admet-2366	204	61	83.18	83.18	NUM
admet-2366	204	62	80.43	80.43	NUM
admet-2366	204	63	81.43	81.43	NUM
admet-2366	204	64	79.72	79.72	NUM
admet-2366	204	65	ng7	ng7	NOUN
admet-2366	205	1	363.25	363.25	NUM
admet-2366	205	2	352.37	352.37	NUM
admet-2366	205	3	63.25	63.25	NUM
admet-2366	205	4	61.16	61.16	NUM
admet-2366	205	5	79.80	79.80	NUM
admet-2366	205	6	79.67	79.67	NUM
admet-2366	205	7	ng8	ng8	NOUN
admet-2366	205	8	160.90	160.90	NUM
admet-2366	205	9	127.44	127.44	NUM
admet-2366	205	10	74.46	74.46	NUM
admet-2366	205	11	80.43	80.43	NUM
admet-2366	205	12	77.34	77.34	NUM
admet-2366	205	13	79.72	79.72	NUM
admet-2366	205	14	ng9	ng9	NOUN
admet-2366	205	15	247.80	247.80	NUM
admet-2366	205	16	225.60	225.60	NUM
admet-2366	205	17	47.00	47.00	NUM
admet-2366	205	18	52.55	52.55	NUM
admet-2366	205	19	73.92	73.92	NUM
admet-2366	205	20	73.97	73.97	NUM
admet-2366	205	21	ng10	ng10	PROPN
admet-2366	205	22	278.96	278.96	NUM
admet-2366	205	23	246.38	246.38	NUM
admet-2366	205	24	75.46	75.46	NUM
admet-2366	205	25	69.06	69.06	NUM
admet-2366	205	26	76.90	76.90	NUM
admet-2366	205	27	76.69	76.69	NUM
admet-2366	206	1	ng11	ng11	PROPN
admet-2366	206	2	186.70	186.70	NUM
admet-2366	206	3	241.48	241.48	NUM
admet-2366	206	4	74.96	74.96	NUM
admet-2366	206	5	75.81	75.81	NUM
admet-2366	206	6	81.57	81.57	NUM
admet-2366	206	7	81.73	81.73	NUM
admet-2366	207	1	ng12	ng12	PROPN
admet-2366	207	2	287.90	287.90	NUM
admet-2366	207	3	266.20	266.20	NUM
admet-2366	207	4	51.15	51.15	NUM
admet-2366	207	5	46.84	46.84	NUM
admet-2366	207	6	71.63	71.63	NUM
admet-2366	207	7	71.56	71.56	NUM
admet-2366	207	8	ng13	ng13	PROPN
admet-2366	207	9	294.80	294.80	NUM
admet-2366	207	10	316.50	316.50	NUM
admet-2366	207	11	61.20	61.20	NUM
admet-2366	207	12	65.51	65.51	NUM
admet-2366	207	13	69.59	69.59	NUM
admet-2366	207	14	69.67	69.67	NUM
admet-2366	208	1	ng14	ng14	PROPN
admet-2366	208	2	250.40	250.40	NUM
admet-2366	208	3	282.98	282.98	NUM
admet-2366	208	4	50.48	50.48	NUM
admet-2366	208	5	56.88	56.88	NUM
admet-2366	208	6	73.39	73.39	NUM
admet-2366	208	7	73.60	73.60	NUM
admet-2366	208	8	ng15	ng15	PROPN
admet-2366	208	9	383.14	383.14	NUM
admet-2366	208	10	328.36	328.36	NUM
admet-2366	208	11	83.14	83.14	NUM
admet-2366	208	12	82.30	82.30	NUM
admet-2366	208	13	76.90	76.90	NUM
admet-2366	208	14	76.74	76.74	NUM
admet-2366	208	15	ng16	ng16	PROPN
admet-2366	208	16	296.50	296.50	NUM
admet-2366	208	17	307.38	307.38	NUM
admet-2366	208	18	79.85	79.85	NUM
admet-2366	208	19	81.94	81.94	NUM
admet-2366	208	20	77.48	77.48	NUM
admet-2366	208	21	77.61	77.61	NUM
admet-2366	208	22	ng17	ng17	PROPN
admet-2366	208	23	380.48	380.48	NUM
admet-2366	208	24	413.56	413.56	NUM
admet-2366	208	25	56.20	56.20	NUM
admet-2366	208	26	52.73	52.73	NUM
admet-2366	208	27	76.90	76.90	NUM
admet-2366	208	28	76.98	76.98	NUM
admet-2366	208	29	the	the	DET
admet-2366	208	30	p	p	NOUN
admet-2366	208	31	-	-	PUNCT
admet-2366	208	32	values	value	NOUN
admet-2366	208	33	less	less	ADJ
admet-2366	208	34	than	than	ADP
admet-2366	208	35	0.0500	0.0500	NUM
admet-2366	208	36	indicate	indicate	VERB
admet-2366	208	37	that	that	SCONJ
admet-2366	208	38	the	the	DET
admet-2366	208	39	model	model	NOUN
admet-2366	208	40	terms	term	NOUN
admet-2366	208	41	are	be	AUX
admet-2366	208	42	significant	significant	ADJ
admet-2366	208	43	.	.	PUNCT
admet-2366	209	1	values	value	NOUN
admet-2366	209	2	greater	great	ADJ
admet-2366	209	3	than	than	ADP
admet-2366	209	4	0.1000	0.1000	NUM
admet-2366	209	5	indicate	indicate	VERB
admet-2366	209	6	the	the	DET
admet-2366	209	7	model	model	NOUN
admet-2366	209	8	terms	term	NOUN
admet-2366	209	9	are	be	AUX
admet-2366	209	10	insignificant	insignificant	ADJ
admet-2366	209	11	(	(	PUNCT
admet-2366	209	12	table	table	NOUN
admet-2366	209	13	3	3	NUM
admet-2366	209	14	)	)	PUNCT
admet-2366	209	15	.	.	PUNCT
admet-2366	210	1	the	the	DET
admet-2366	210	2	anova	anova	PROPN
admet-2366	210	3	data	datum	NOUN
admet-2366	210	4	of	of	ADP
admet-2366	210	5	the	the	DET
admet-2366	210	6	quadratic	quadratic	ADJ
admet-2366	210	7	model	model	NOUN
admet-2366	210	8	for	for	ADP
admet-2366	210	9	encapsulation	encapsulation	NOUN
admet-2366	210	10	efficiency	efficiency	NOUN
admet-2366	210	11	(	(	PUNCT
admet-2366	210	12	%	%	INTJ
admet-2366	210	13	)	)	PUNCT
admet-2366	210	14	implies	imply	VERB
admet-2366	210	15	the	the	DET
admet-2366	210	16	model	model	NOUN
admet-2366	210	17	is	be	AUX
admet-2366	210	18	significant	significant	ADJ
admet-2366	210	19	with	with	ADP
admet-2366	210	20	a	a	DET
admet-2366	210	21	model	model	NOUN
admet-2366	210	22	f	f	NOUN
admet-2366	210	23	-	-	PUNCT
admet-2366	210	24	value	value	NOUN
admet-2366	210	25	of	of	ADP
admet-2366	210	26	4.62	4.62	NUM
admet-2366	210	27	.	.	PUNCT
admet-2366	211	1	in	in	ADP
admet-2366	211	2	this	this	DET
admet-2366	211	3	case	case	NOUN
admet-2366	211	4	,	,	PUNCT
admet-2366	211	5	x2	x2	PROPN
admet-2366	211	6	and	and	CCONJ
admet-2366	211	7	x1²	x1²	NOUN
admet-2366	211	8	are	be	AUX
admet-2366	211	9	significant	significant	ADJ
admet-2366	211	10	model	model	NOUN
admet-2366	211	11	terms	term	NOUN
admet-2366	211	12	.	.	PUNCT
admet-2366	212	1	the	the	DET
admet-2366	212	2	lack	lack	NOUN
admet-2366	212	3	of	of	ADP
admet-2366	212	4	fit	fit	ADJ
admet-2366	212	5	f	f	NOUN
admet-2366	212	6	-	-	PUNCT
admet-2366	212	7	value	value	NOUN
admet-2366	212	8	of	of	ADP
admet-2366	212	9	1.34	1.34	NUM
admet-2366	212	10	implies	imply	VERB
admet-2366	212	11	the	the	DET
admet-2366	212	12	lack	lack	NOUN
admet-2366	212	13	of	of	ADP
admet-2366	212	14	fit	fit	NOUN
admet-2366	212	15	is	be	AUX
admet-2366	212	16	insignificant	insignificant	ADJ
admet-2366	212	17	relative	relative	ADJ
admet-2366	212	18	to	to	ADP
admet-2366	212	19	the	the	DET
admet-2366	212	20	pure	pure	ADJ
admet-2366	212	21	error	error	NOUN
admet-2366	212	22	.	.	PUNCT
admet-2366	213	1	there	there	PRON
admet-2366	213	2	is	be	VERB
admet-2366	213	3	a	a	DET
admet-2366	213	4	38.00	38.00	NUM
admet-2366	213	5	%	%	NOUN
admet-2366	213	6	chance	chance	NOUN
admet-2366	213	7	that	that	SCONJ
admet-2366	213	8	a	a	DET
admet-2366	213	9	large	large	ADJ
admet-2366	213	10	lack	lack	NOUN
admet-2366	213	11	of	of	ADP
admet-2366	213	12	fit	fit	ADJ
admet-2366	213	13	f	f	NOUN
admet-2366	213	14	-	-	PUNCT
admet-2366	213	15	value	value	NOUN
admet-2366	213	16	could	could	AUX
admet-2366	213	17	occur	occur	VERB
admet-2366	213	18	due	due	ADJ
admet-2366	213	19	to	to	ADP
admet-2366	213	20	noise	noise	NOUN
admet-2366	213	21	.	.	PUNCT
admet-2366	214	1	the	the	DET
admet-2366	214	2	r²	r²	NOUN
admet-2366	214	3	,	,	PUNCT
admet-2366	214	4	adjusted	adjusted	ADJ
admet-2366	214	5	r²	r²	NOUN
admet-2366	214	6	,	,	PUNCT
admet-2366	214	7	and	and	CCONJ
admet-2366	214	8	predicted	predict	VERB
admet-2366	214	9	r²	r²	NOUN
admet-2366	214	10	values	value	NOUN
admet-2366	214	11	for	for	ADP
admet-2366	214	12	the	the	DET
admet-2366	214	13	anova	anova	PROPN
admet-2366	214	14	data	data	PROPN
admet-2366	214	15	of	of	ADP
admet-2366	214	16	encapsulation	encapsulation	NOUN
admet-2366	214	17	efficiency	efficiency	NOUN
admet-2366	214	18	were	be	AUX
admet-2366	214	19	0.8558	0.8558	NUM
admet-2366	214	20	,	,	PUNCT
admet-2366	214	21	0.6704	0.6704	NUM
admet-2366	214	22	and	and	CCONJ
admet-2366	214	23	-0.2682	-0.2682	NOUN
admet-2366	214	24	%	%	INTJ
admet-2366	214	25	,	,	PUNCT
admet-2366	214	26	respectively	respectively	ADV
admet-2366	214	27	.	.	PUNCT
admet-2366	215	1	adequate	adequate	ADJ
admet-2366	215	2	precision	precision	NOUN
admet-2366	215	3	(	(	PUNCT
admet-2366	215	4	signal	signal	NOUN
admet-2366	215	5	-	-	PUNCT
admet-2366	215	6	to	to	ADP
admet-2366	215	7	-	-	PUNCT
admet-2366	215	8	noise	noise	NOUN
admet-2366	215	9	ratio	ratio	NOUN
admet-2366	215	10	)	)	PUNCT
admet-2366	215	11	greater	great	ADJ
admet-2366	215	12	than	than	ADP
admet-2366	215	13	4	4	NUM
admet-2366	215	14	is	be	AUX
admet-2366	215	15	desirable	desirable	ADJ
admet-2366	215	16	.	.	PUNCT
admet-2366	216	1	a	a	DET
admet-2366	216	2	ratio	ratio	NOUN
admet-2366	216	3	of	of	ADP
admet-2366	216	4	5.905	5.905	NUM
admet-2366	216	5	indicates	indicate	VERB
admet-2366	216	6	an	an	DET
admet-2366	216	7	adequate	adequate	ADJ
admet-2366	216	8	signal	signal	NOUN
admet-2366	216	9	.	.	PUNCT
admet-2366	217	1	in	in	ADP
admet-2366	217	2	the	the	DET
admet-2366	217	3	case	case	NOUN
admet-2366	217	4	of	of	ADP
admet-2366	217	5	particle	particle	NOUN
admet-2366	217	6	size	size	NOUN
admet-2366	217	7	,	,	PUNCT
admet-2366	217	8	the	the	DET
admet-2366	217	9	model	model	NOUN
admet-2366	217	10	f	f	NOUN
admet-2366	217	11	-	-	PUNCT
admet-2366	217	12	value	value	NOUN
admet-2366	217	13	of	of	ADP
admet-2366	217	14	3.95	3.95	NUM
admet-2366	217	15	implies	imply	VERB
admet-2366	217	16	the	the	DET
admet-2366	217	17	model	model	NOUN
admet-2366	217	18	is	be	AUX
admet-2366	217	19	admet	admet	PROPN
admet-2366	217	20	&	&	CCONJ
admet-2366	217	21	dmpk	dmpk	PROPN
admet-2366	217	22	12(4	12(4	PROPN
admet-2366	217	23	)	)	PUNCT
admet-2366	217	24	(	(	PUNCT
admet-2366	217	25	2024	2024	NUM
admet-2366	217	26	)	)	PUNCT
admet-2366	217	27	657	657	NUM
admet-2366	217	28	-	-	SYM
admet-2366	217	29	677	677	NUM
admet-2366	217	30	optimizing	optimizing	NOUN
admet-2366	217	31	gefitinib	gefitinib	NOUN
admet-2366	217	32	nanoliposomes	nanoliposomes	ADV
admet-2366	217	33	doi	doi	ADV
admet-2366	217	34	:	:	PUNCT
admet-2366	217	35	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PROPN
admet-2366	217	36	665	665	NUM
admet-2366	217	37	significant	significant	ADJ
admet-2366	217	38	.	.	PUNCT
admet-2366	218	1	in	in	ADP
admet-2366	218	2	this	this	DET
admet-2366	218	3	case	case	NOUN
admet-2366	218	4	,	,	PUNCT
admet-2366	218	5	x1x3	x1x3	X
admet-2366	218	6	,	,	PUNCT
admet-2366	218	7	x2²	x2²	PROPN
admet-2366	218	8	,	,	PUNCT
admet-2366	218	9	and	and	CCONJ
admet-2366	218	10	x3²	x3²	PROPN
admet-2366	218	11	are	be	AUX
admet-2366	218	12	significant	significant	ADJ
admet-2366	218	13	model	model	NOUN
admet-2366	218	14	terms	term	NOUN
admet-2366	218	15	.	.	PUNCT
admet-2366	219	1	the	the	DET
admet-2366	219	2	lack	lack	NOUN
admet-2366	219	3	of	of	ADP
admet-2366	219	4	fit	fit	ADJ
admet-2366	219	5	f	f	NOUN
admet-2366	219	6	-	-	PUNCT
admet-2366	219	7	value	value	NOUN
admet-2366	219	8	of	of	ADP
admet-2366	219	9	4.12	4.12	NUM
admet-2366	219	10	implies	imply	VERB
admet-2366	219	11	that	that	SCONJ
admet-2366	219	12	it	it	PRON
admet-2366	219	13	is	be	AUX
admet-2366	219	14	not	not	PART
admet-2366	219	15	significant	significant	ADJ
admet-2366	219	16	relative	relative	ADJ
admet-2366	219	17	to	to	ADP
admet-2366	219	18	the	the	DET
admet-2366	219	19	pure	pure	ADJ
admet-2366	219	20	error	error	NOUN
admet-2366	219	21	.	.	PUNCT
admet-2366	220	1	there	there	PRON
admet-2366	220	2	is	be	VERB
admet-2366	220	3	a	a	DET
admet-2366	220	4	10.24	10.24	NUM
admet-2366	220	5	%	%	NOUN
admet-2366	220	6	chance	chance	NOUN
admet-2366	220	7	that	that	SCONJ
admet-2366	220	8	a	a	DET
admet-2366	220	9	large	large	ADJ
admet-2366	220	10	lack	lack	NOUN
admet-2366	220	11	of	of	ADP
admet-2366	220	12	fit	fit	ADJ
admet-2366	220	13	f	f	NOUN
admet-2366	220	14	-	-	PUNCT
admet-2366	220	15	value	value	NOUN
admet-2366	220	16	could	could	AUX
admet-2366	220	17	occur	occur	VERB
admet-2366	220	18	due	due	ADJ
admet-2366	220	19	to	to	ADP
admet-2366	220	20	noise	noise	NOUN
admet-2366	220	21	.	.	PUNCT
admet-2366	221	1	the	the	DET
admet-2366	221	2	r²	r²	NOUN
admet-2366	221	3	,	,	PUNCT
admet-2366	221	4	adjusted	adjusted	ADJ
admet-2366	221	5	r²	r²	NOUN
admet-2366	221	6	,	,	PUNCT
admet-2366	221	7	and	and	CCONJ
admet-2366	221	8	predicted	predict	VERB
admet-2366	221	9	r²	r²	NOUN
admet-2366	221	10	values	value	NOUN
admet-2366	221	11	for	for	ADP
admet-2366	221	12	the	the	DET
admet-2366	221	13	anova	anova	PROPN
admet-2366	221	14	data	data	PROPN
admet-2366	221	15	of	of	ADP
admet-2366	221	16	encapsulation	encapsulation	NOUN
admet-2366	221	17	efficiency	efficiency	NOUN
admet-2366	221	18	were	be	AUX
admet-2366	221	19	0.8356	0.8356	NUM
admet-2366	221	20	,	,	PUNCT
admet-2366	221	21	0.6243	0.6243	NUM
admet-2366	221	22	,	,	PUNCT
admet-2366	221	23	and	and	CCONJ
admet-2366	221	24	-1.0500	-1.0500	NOUN
admet-2366	221	25	%	%	INTJ
admet-2366	221	26	,	,	PUNCT
admet-2366	221	27	respectively	respectively	ADV
admet-2366	221	28	.	.	PUNCT
admet-2366	222	1	the	the	DET
admet-2366	222	2	ratio	ratio	NOUN
admet-2366	222	3	of	of	ADP
admet-2366	222	4	adequate	adequate	ADJ
admet-2366	222	5	precision	precision	NOUN
admet-2366	222	6	(	(	PUNCT
admet-2366	222	7	6.1640	6.1640	NUM
admet-2366	222	8	)	)	PUNCT
admet-2366	222	9	indicates	indicate	VERB
admet-2366	222	10	an	an	DET
admet-2366	222	11	adequate	adequate	ADJ
admet-2366	222	12	signal	signal	NOUN
admet-2366	222	13	.	.	PUNCT
admet-2366	223	1	table	table	NOUN
admet-2366	223	2	3	3	NUM
admet-2366	223	3	.	.	PUNCT
admet-2366	224	1	anova	anova	PROPN
admet-2366	224	2	results	result	VERB
admet-2366	224	3	for	for	ADP
admet-2366	224	4	quadratic	quadratic	ADJ
admet-2366	224	5	model	model	NOUN
admet-2366	224	6	of	of	ADP
admet-2366	224	7	particle	particle	NOUN
admet-2366	224	8	size	size	NOUN
admet-2366	224	9	,	,	PUNCT
admet-2366	224	10	encapsulation	encapsulation	NOUN
admet-2366	224	11	efficiency	efficiency	NOUN
admet-2366	224	12	and	and	CCONJ
admet-2366	224	13	cumulative	cumulative	ADJ
admet-2366	224	14	drug	drug	NOUN
admet-2366	224	15	release	release	NOUN
admet-2366	224	16	.	.	PUNCT
admet-2366	225	1	source	source	NOUN
admet-2366	225	2	sum	sum	NOUN
admet-2366	225	3	of	of	ADP
admet-2366	225	4	squares	square	NOUN
admet-2366	225	5	df	df	PROPN
admet-2366	225	6	mean	mean	VERB
admet-2366	225	7	square	square	ADJ
admet-2366	226	1	f	f	NOUN
admet-2366	226	2	-	-	PUNCT
admet-2366	226	3	value	value	NOUN
admet-2366	226	4	p	p	NOUN
admet-2366	226	5	-	-	PUNCT
admet-2366	226	6	value	value	NOUN
admet-2366	226	7	remark	remark	NOUN
admet-2366	226	8	encapsulation	encapsulation	NOUN
admet-2366	226	9	efficiency	efficiency	NOUN
admet-2366	226	10	,	,	PUNCT
admet-2366	226	11	%	%	NOUN
admet-2366	226	12	model	model	NOUN
admet-2366	226	13	2546.21	2546.21	NUM
admet-2366	226	14	9	9	NUM
admet-2366	226	15	282.91	282.91	NUM
admet-2366	226	16	4.62	4.62	NUM
admet-2366	226	17	0.0281	0.0281	NUM
admet-2366	226	18	significant	significant	ADJ
admet-2366	226	19	x1	x1	PROPN
admet-2366	226	20	50.80	50.80	NUM
admet-2366	226	21	1	1	NUM
admet-2366	226	22	50.80	50.80	NUM
admet-2366	227	1	0.8289	0.8289	NUM
admet-2366	227	2	0.3929	0.3929	NUM
admet-2366	227	3	x2	x2	NOUN
admet-2366	227	4	371.69	371.69	NUM
admet-2366	227	5	1	1	NUM
admet-2366	227	6	371.69	371.69	NUM
admet-2366	227	7	6.06	6.06	NUM
admet-2366	227	8	0.0433	0.0433	NUM
admet-2366	227	9	x3	x3	PROPN
admet-2366	227	10	102.03	102.03	NUM
admet-2366	227	11	1	1	NUM
admet-2366	227	12	102.03	102.03	NUM
admet-2366	227	13	1.66	1.66	NUM
admet-2366	227	14	0.2380	0.2380	NUM
admet-2366	227	15	x1x2	x1x2	PUNCT
admet-2366	227	16	0.4556	0.4556	NUM
admet-2366	227	17	1	1	NUM
admet-2366	227	18	0.4556	0.4556	NUM
admet-2366	227	19	0.0074	0.0074	NUM
admet-2366	227	20	0.9337	0.9337	NUM
admet-2366	227	21	x1x3	x1x3	SYM
admet-2366	227	22	84.36	84.36	NUM
admet-2366	227	23	1	1	NUM
admet-2366	227	24	84.36	84.36	NUM
admet-2366	227	25	1.38	1.38	NUM
admet-2366	227	26	0.2791	0.2791	NUM
admet-2366	227	27	x2x3	x2x3	PUNCT
admet-2366	228	1	56.25	56.25	NUM
admet-2366	228	2	1	1	NUM
admet-2366	228	3	56.25	56.25	NUM
admet-2366	228	4	0.9178	0.9178	NUM
admet-2366	228	5	0.3700	0.3700	NUM
admet-2366	228	6	x1²	x1²	NOUN
admet-2366	228	7	1755.35	1755.35	NUM
admet-2366	228	8	1	1	NUM
admet-2366	228	9	1755.35	1755.35	NUM
admet-2366	228	10	28.64	28.64	NUM
admet-2366	228	11	0.0011	0.0011	NUM
admet-2366	228	12	x2²	x2²	PROPN
admet-2366	228	13	51.45	51.45	NUM
admet-2366	228	14	1	1	NUM
admet-2366	228	15	51.45	51.45	NUM
admet-2366	228	16	0.8394	0.8394	NUM
admet-2366	228	17	0.3900	0.3900	NUM
admet-2366	228	18	x3²	x3²	PROPN
admet-2366	228	19	11.19	11.19	NUM
admet-2366	228	20	1	1	NUM
admet-2366	228	21	11.19	11.19	NUM
admet-2366	228	22	0.1826	0.1826	NUM
admet-2366	228	23	0.6820	0.6820	NUM
admet-2366	228	24	residual	residual	ADJ
admet-2366	228	25	429.04	429.04	NUM
admet-2366	228	26	7	7	NUM
admet-2366	228	27	61.29	61.29	NUM
admet-2366	228	28	lack	lack	NOUN
admet-2366	228	29	of	of	ADP
admet-2366	228	30	fit	fit	ADJ
admet-2366	228	31	214.92	214.92	NUM
admet-2366	228	32	3	3	NUM
admet-2366	228	33	71.64	71.64	NUM
admet-2366	228	34	1.34	1.34	NUM
admet-2366	228	35	0.3800	0.3800	NUM
admet-2366	228	36	not	not	PART
admet-2366	228	37	significant	significant	ADJ
admet-2366	228	38	pure	pure	ADJ
admet-2366	228	39	error	error	NOUN
admet-2366	228	40	214.11	214.11	NUM
admet-2366	228	41	4	4	NUM
admet-2366	228	42	53.53	53.53	NUM
admet-2366	228	43	cor	cor	X
admet-2366	228	44	total	total	PROPN
admet-2366	228	45	2975.25	2975.25	NUM
admet-2366	228	46	16	16	NUM
admet-2366	228	47	particle	particle	NOUN
admet-2366	228	48	size	size	NOUN
admet-2366	228	49	,	,	PUNCT
admet-2366	228	50	nm	nm	NOUN
admet-2366	228	51	model	model	NOUN
admet-2366	228	52	131800.00	131800.00	NUM
admet-2366	228	53	9	9	NUM
admet-2366	228	54	14640.44	14640.44	NUM
admet-2366	228	55	3.95	3.95	NUM
admet-2366	228	56	0.0418	0.0418	NUM
admet-2366	228	57	significant	significant	ADJ
admet-2366	228	58	x1	x1	PROPN
admet-2366	228	59	6027.47	6027.47	NUM
admet-2366	228	60	1	1	NUM
admet-2366	228	61	6027.47	6027.47	NUM
admet-2366	228	62	1.63	1.63	NUM
admet-2366	228	63	0.2427	0.2427	NUM
admet-2366	228	64	x2	x2	NOUN
admet-2366	228	65	1154.16	1154.16	NUM
admet-2366	228	66	1	1	NUM
admet-2366	228	67	1154.16	1154.16	NUM
admet-2366	228	68	0.3117	0.3117	NUM
admet-2366	228	69	0.5940	0.5940	NUM
admet-2366	228	70	x3	x3	NOUN
admet-2366	228	71	3776.67	3776.67	NUM
admet-2366	228	72	1	1	NUM
admet-2366	228	73	3776.67	3776.67	NUM
admet-2366	228	74	1.02	1.02	NUM
admet-2366	228	75	0.3461	0.3461	NUM
admet-2366	228	76	x1x2	x1x2	PUNCT
admet-2366	228	77	4070.44	4070.44	NUM
admet-2366	228	78	1	1	NUM
admet-2366	228	79	4070.44	4070.44	NUM
admet-2366	228	80	1.10	1.10	NUM
admet-2366	228	81	0.3292	0.3292	NUM
admet-2366	228	82	x1x3	x1x3	NUM
admet-2366	228	83	21375.90	21375.90	NUM
admet-2366	228	84	1	1	NUM
admet-2366	228	85	21375.90	21375.90	NUM
admet-2366	228	86	5.77	5.77	NUM
admet-2366	228	87	0.0473	0.0473	NUM
admet-2366	228	88	x2x3	x2x3	X
admet-2366	228	89	2020.95	2020.95	NUM
admet-2366	228	90	1	1	NUM
admet-2366	228	91	2020.95	2020.95	NUM
admet-2366	228	92	0.5458	0.5458	NUM
admet-2366	228	93	0.4841	0.4841	NUM
admet-2366	228	94	x1²	x1²	NOUN
admet-2366	228	95	13036.16	13036.16	NUM
admet-2366	228	96	1	1	NUM
admet-2366	228	97	13036.16	13036.16	NUM
admet-2366	228	98	3.52	3.52	NUM
admet-2366	228	99	0.1027	0.1027	NUM
admet-2366	228	100	x2²	x2²	PROPN
admet-2366	228	101	20759.99	20759.99	NUM
admet-2366	228	102	1	1	NUM
admet-2366	228	103	20759.99	20759.99	NUM
admet-2366	228	104	5.61	5.61	NUM
admet-2366	228	105	0.0498	0.0498	NUM
admet-2366	228	106	x3²	x3²	NUM
admet-2366	229	1	50706.81	50706.81	NUM
admet-2366	229	2	1	1	NUM
admet-2366	229	3	50706.81	50706.81	NUM
admet-2366	229	4	13.70	13.70	NUM
admet-2366	229	5	0.0076	0.0076	NUM
admet-2366	229	6	residual	residual	ADJ
admet-2366	229	7	25917.12	25917.12	NUM
admet-2366	229	8	7	7	NUM
admet-2366	229	9	3702.45	3702.45	NUM
admet-2366	229	10	lack	lack	NOUN
admet-2366	229	11	of	of	ADP
admet-2366	229	12	fit	fit	ADJ
admet-2366	229	13	19584.50	19584.50	NUM
admet-2366	229	14	3	3	NUM
admet-2366	229	15	6528.17	6528.17	NUM
admet-2366	229	16	4.12	4.12	NUM
admet-2366	229	17	0.1024	0.1024	NUM
admet-2366	229	18	not	not	PART
admet-2366	229	19	significant	significant	ADJ
admet-2366	229	20	pure	pure	ADJ
admet-2366	229	21	error	error	NOUN
admet-2366	229	22	6332.61	6332.61	NUM
admet-2366	229	23	4	4	NUM
admet-2366	229	24	1583.15	1583.15	NUM
admet-2366	229	25	cor	cor	PROPN
admet-2366	229	26	total	total	VERB
admet-2366	229	27	157700.00	157700.00	NUM
admet-2366	229	28	16	16	NUM
admet-2366	229	29	cumulative	cumulative	ADJ
admet-2366	229	30	drug	drug	NOUN
admet-2366	229	31	release	release	NOUN
admet-2366	229	32	,	,	PUNCT
admet-2366	229	33	%	%	NOUN
admet-2366	229	34	model	model	NOUN
admet-2366	229	35	235.34	235.34	NUM
admet-2366	229	36	9	9	NUM
admet-2366	229	37	26.15	26.15	NUM
admet-2366	229	38	5.08	5.08	NUM
admet-2366	229	39	0.0217	0.0217	NUM
admet-2366	229	40	significant	significant	ADJ
admet-2366	229	41	x1	x1	ADJ
admet-2366	229	42	5.30	5.30	NUM
admet-2366	229	43	1	1	NUM
admet-2366	229	44	5.30	5.30	NUM
admet-2366	229	45	1.03	1.03	NUM
admet-2366	229	46	0.3439	0.3439	NUM
admet-2366	230	1	x2	x2	NOUN
admet-2366	230	2	24.75	24.75	NUM
admet-2366	230	3	1	1	NUM
admet-2366	230	4	24.75	24.75	NUM
admet-2366	230	5	4.81	4.81	NUM
admet-2366	230	6	0.0643	0.0643	NUM
admet-2366	230	7	x3	x3	ADJ
admet-2366	230	8	4.29	4.29	NUM
admet-2366	230	9	1	1	NUM
admet-2366	230	10	4.29	4.29	NUM
admet-2366	230	11	0.8346	0.8346	NUM
admet-2366	230	12	0.3913	0.3913	NUM
admet-2366	230	13	x1x2	x1x2	PUNCT
admet-2366	230	14	0.6241	0.6241	NUM
admet-2366	230	15	1	1	NUM
admet-2366	230	16	0.6241	0.6241	NUM
admet-2366	230	17	0.1213	0.1213	NUM
admet-2366	230	18	0.7378	0.7378	NUM
admet-2366	230	19	x1x3	x1x3	NUM
admet-2366	230	20	3.08	3.08	NUM
admet-2366	230	21	1	1	NUM
admet-2366	230	22	3.08	3.08	NUM
admet-2366	230	23	0.5989	0.5989	NUM
admet-2366	230	24	0.4643	0.4643	NUM
admet-2366	230	25	x2x3	x2x3	PUNCT
admet-2366	231	1	0.3540	0.3540	NUM
admet-2366	231	2	1	1	NUM
admet-2366	231	3	0.3540	0.3540	NUM
admet-2366	231	4	0.0688	0.0688	NUM
admet-2366	231	5	0.8006	0.8006	NUM
admet-2366	231	6	x1²	x1²	NOUN
admet-2366	231	7	142.28	142.28	NUM
admet-2366	231	8	1	1	NUM
admet-2366	231	9	142.28	142.28	NUM
admet-2366	231	10	27.66	27.66	NUM
admet-2366	231	11	0.0012	0.0012	NUM
admet-2366	231	12	x2²	x2²	PROPN
admet-2366	231	13	35.36	35.36	NUM
admet-2366	231	14	1	1	NUM
admet-2366	231	15	35.36	35.36	NUM
admet-2366	231	16	6.88	6.88	NUM
admet-2366	231	17	0.0343	0.0343	NUM
admet-2366	231	18	x3²	x3²	PROPN
admet-2366	231	19	18.91	18.91	NUM
admet-2366	231	20	1	1	NUM
admet-2366	231	21	18.91	18.91	NUM
admet-2366	231	22	3.68	3.68	NUM
admet-2366	231	23	0.0967	0.0967	NUM
admet-2366	231	24	residual	residual	ADJ
admet-2366	231	25	36.00	36.00	NUM
admet-2366	231	26	7	7	NUM
admet-2366	231	27	5.14	5.14	NUM
admet-2366	231	28	lack	lack	NOUN
admet-2366	231	29	of	of	ADP
admet-2366	231	30	fit	fit	ADJ
admet-2366	231	31	0.2017	0.2017	NUM
admet-2366	231	32	3	3	NUM
admet-2366	231	33	0.0672	0.0672	NUM
admet-2366	232	1	0.0075	0.0075	NUM
admet-2366	232	2	0.9990	0.9990	NUM
admet-2366	232	3	not	not	PART
admet-2366	232	4	significant	significant	ADJ
admet-2366	232	5	pure	pure	ADJ
admet-2366	232	6	error	error	NOUN
admet-2366	232	7	35.80	35.80	NUM
admet-2366	232	8	4	4	NUM
admet-2366	232	9	8.95	8.95	NUM
admet-2366	232	10	cor	cor	NOUN
admet-2366	232	11	total	total	NOUN
admet-2366	232	12	271.35	271.35	NUM
admet-2366	232	13	16	16	NUM
admet-2366	232	14	the	the	DET
admet-2366	232	15	model	model	NOUN
admet-2366	232	16	f	f	NOUN
admet-2366	232	17	-	-	PUNCT
admet-2366	232	18	value	value	NOUN
admet-2366	232	19	of	of	ADP
admet-2366	232	20	5.08	5.08	NUM
admet-2366	232	21	implies	imply	VERB
admet-2366	232	22	that	that	SCONJ
admet-2366	232	23	the	the	DET
admet-2366	232	24	developed	developed	ADJ
admet-2366	232	25	model	model	NOUN
admet-2366	232	26	for	for	ADP
admet-2366	232	27	cumulative	cumulative	ADJ
admet-2366	232	28	drug	drug	NOUN
admet-2366	232	29	release	release	NOUN
admet-2366	232	30	is	be	AUX
admet-2366	232	31	significant	significant	ADJ
admet-2366	232	32	.	.	PUNCT
admet-2366	233	1	in	in	ADP
admet-2366	233	2	this	this	DET
admet-2366	233	3	case	case	NOUN
admet-2366	233	4	,	,	PUNCT
admet-2366	233	5	x1²	x1²	NOUN
admet-2366	233	6	and	and	CCONJ
admet-2366	233	7	x2²	x2²	PROPN
admet-2366	233	8	are	be	AUX
admet-2366	233	9	significant	significant	ADJ
admet-2366	233	10	model	model	NOUN
admet-2366	233	11	terms	term	NOUN
admet-2366	233	12	.	.	PUNCT
admet-2366	234	1	the	the	DET
admet-2366	234	2	lack	lack	NOUN
admet-2366	234	3	of	of	ADP
admet-2366	234	4	fit	fit	ADJ
admet-2366	234	5	f	f	NOUN
admet-2366	234	6	-	-	PUNCT
admet-2366	234	7	value	value	NOUN
admet-2366	234	8	of	of	ADP
admet-2366	234	9	0.01	0.01	NUM
admet-2366	234	10	implies	imply	VERB
admet-2366	234	11	the	the	DET
admet-2366	234	12	lack	lack	NOUN
admet-2366	234	13	of	of	ADP
admet-2366	234	14	fit	fit	NOUN
admet-2366	234	15	is	be	AUX
admet-2366	234	16	not	not	PART
admet-2366	234	17	significant	significant	ADJ
admet-2366	234	18	relative	relative	ADJ
admet-2366	234	19	to	to	ADP
admet-2366	234	20	the	the	DET
admet-2366	234	21	pure	pure	ADJ
admet-2366	234	22	error	error	NOUN
admet-2366	234	23	.	.	PUNCT
admet-2366	235	1	there	there	PRON
admet-2366	235	2	is	be	VERB
admet-2366	235	3	a	a	DET
admet-2366	235	4	99.90	99.90	NUM
admet-2366	235	5	%	%	NOUN
admet-2366	235	6	chance	chance	NOUN
admet-2366	235	7	that	that	SCONJ
admet-2366	235	8	a	a	DET
admet-2366	235	9	large	large	ADJ
admet-2366	235	10	lack	lack	NOUN
admet-2366	235	11	of	of	ADP
admet-2366	235	12	fit	fit	ADJ
admet-2366	235	13	f	f	NOUN
admet-2366	235	14	-	-	PUNCT
admet-2366	235	15	value	value	NOUN
admet-2366	235	16	could	could	AUX
admet-2366	235	17	occur	occur	VERB
admet-2366	235	18	due	due	ADJ
admet-2366	235	19	to	to	ADP
admet-2366	235	20	noise	noise	NOUN
admet-2366	235	21	.	.	PUNCT
admet-2366	236	1	the	the	DET
admet-2366	236	2	r²	r²	NOUN
admet-2366	236	3	,	,	PUNCT
admet-2366	236	4	adjusted	adjusted	ADJ
admet-2366	236	5	r²	r²	NOUN
admet-2366	236	6	,	,	PUNCT
admet-2366	236	7	and	and	CCONJ
admet-2366	236	8	predicted	predict	VERB
admet-2366	236	9	r²	r²	NOUN
admet-2366	236	10	values	value	NOUN
admet-2366	236	11	for	for	ADP
admet-2366	236	12	the	the	DET
admet-2366	236	13	anova	anova	PROPN
admet-2366	236	14	data	data	PROPN
admet-2366	236	15	of	of	ADP
admet-2366	236	16	encapsulation	encapsulation	NOUN
admet-2366	236	17	efficiency	efficiency	NOUN
admet-2366	236	18	(	(	PUNCT
admet-2366	236	19	%	%	INTJ
admet-2366	236	20	)	)	PUNCT
admet-2366	236	21	were	be	AUX
admet-2366	236	22	0.8673	0.8673	NUM
admet-2366	236	23	,	,	PUNCT
admet-2366	236	24	0.6967	0.6967	NUM
admet-2366	236	25	,	,	PUNCT
admet-2366	236	26	and	and	CCONJ
admet-2366	236	27	0.7820	0.7820	NUM
admet-2366	236	28	,	,	PUNCT
admet-2366	236	29	respectively	respectively	ADV
admet-2366	236	30	.	.	PUNCT
admet-2366	237	1	the	the	DET
admet-2366	237	2	predicted	predict	VERB
admet-2366	237	3	r²	r²	NOUN
admet-2366	237	4	of	of	ADP
admet-2366	237	5	0.7820	0.7820	NUM
admet-2366	237	6	is	be	AUX
admet-2366	237	7	in	in	ADP
admet-2366	237	8	reasonable	reasonable	ADJ
admet-2366	237	9	agreement	agreement	NOUN
admet-2366	237	10	with	with	ADP
admet-2366	237	11	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PROPN
admet-2366	237	12	s.	s.	PROPN
admet-2366	237	13	rohilla	rohilla	PROPN
admet-2366	237	14	et	et	PROPN
admet-2366	237	15	al	al	PROPN
admet-2366	237	16	.	.	PROPN
admet-2366	237	17	admet	admet	PROPN
admet-2366	237	18	&	&	CCONJ
admet-2366	237	19	dmpk	dmpk	PROPN
admet-2366	237	20	12(4	12(4	PROPN
admet-2366	237	21	)	)	PUNCT
admet-2366	237	22	(	(	PUNCT
admet-2366	237	23	2024	2024	NUM
admet-2366	237	24	)	)	PUNCT
admet-2366	237	25	657	657	NUM
admet-2366	237	26	-	-	SYM
admet-2366	237	27	677	677	NUM
admet-2366	237	28	666	666	NUM
admet-2366	237	29	the	the	DET
admet-2366	237	30	adjusted	adjust	VERB
admet-2366	237	31	r²	r²	NOUN
admet-2366	237	32	of	of	ADP
admet-2366	237	33	0.6967	0.6967	NUM
admet-2366	237	34	;	;	PUNCT
admet-2366	237	35	i.e.	i.e.	X
admet-2366	237	36	,	,	PUNCT
admet-2366	237	37	the	the	DET
admet-2366	237	38	difference	difference	NOUN
admet-2366	237	39	is	be	AUX
admet-2366	237	40	less	less	ADJ
admet-2366	237	41	than	than	ADP
admet-2366	237	42	0.2	0.2	NUM
admet-2366	237	43	.	.	PUNCT
admet-2366	238	1	the	the	DET
admet-2366	238	2	ratio	ratio	NOUN
admet-2366	238	3	of	of	ADP
admet-2366	238	4	7.4158	7.4158	NUM
admet-2366	238	5	indicates	indicate	VERB
admet-2366	238	6	an	an	DET
admet-2366	238	7	adequate	adequate	ADJ
admet-2366	238	8	signal	signal	NOUN
admet-2366	238	9	.	.	PUNCT
admet-2366	239	1	the	the	DET
admet-2366	239	2	results	result	NOUN
admet-2366	239	3	suggested	suggest	VERB
admet-2366	239	4	that	that	SCONJ
admet-2366	239	5	the	the	DET
admet-2366	239	6	developed	develop	VERB
admet-2366	239	7	models	model	NOUN
admet-2366	239	8	can	can	AUX
admet-2366	239	9	be	be	AUX
admet-2366	239	10	used	use	VERB
admet-2366	239	11	to	to	PART
admet-2366	239	12	navigate	navigate	VERB
admet-2366	239	13	the	the	DET
admet-2366	239	14	design	design	NOUN
admet-2366	239	15	space	space	NOUN
admet-2366	239	16	.	.	PUNCT
admet-2366	240	1	thermal	thermal	ADJ
admet-2366	240	2	analysis	analysis	NOUN
admet-2366	240	3	thermal	thermal	ADJ
admet-2366	240	4	analysis	analysis	NOUN
admet-2366	240	5	was	be	AUX
admet-2366	240	6	performed	perform	VERB
admet-2366	240	7	to	to	PART
admet-2366	240	8	verify	verify	VERB
admet-2366	240	9	the	the	DET
admet-2366	240	10	amorphous	amorphous	ADJ
admet-2366	240	11	or	or	CCONJ
admet-2366	240	12	crystalline	crystalline	ADJ
admet-2366	240	13	performance	performance	NOUN
admet-2366	240	14	of	of	ADP
admet-2366	240	15	gefitinib	gefitinib	NOUN
admet-2366	240	16	(	(	PUNCT
admet-2366	240	17	before	before	ADP
admet-2366	240	18	and	and	CCONJ
admet-2366	240	19	after	after	ADP
admet-2366	240	20	entrapment	entrapment	NOUN
admet-2366	240	21	in	in	ADP
admet-2366	240	22	nanoliposomes	nanoliposome	NOUN
admet-2366	240	23	)	)	PUNCT
admet-2366	240	24	.	.	PUNCT
admet-2366	241	1	in	in	ADP
admet-2366	241	2	the	the	DET
admet-2366	241	3	dsc	dsc	PROPN
admet-2366	241	4	thermogram	thermogram	NOUN
admet-2366	241	5	,	,	PUNCT
admet-2366	241	6	a	a	DET
admet-2366	241	7	spiky	spiky	NOUN
admet-2366	241	8	endothermic	endothermic	NOUN
admet-2366	241	9	peak	peak	NOUN
admet-2366	241	10	was	be	AUX
admet-2366	241	11	shown	show	VERB
admet-2366	241	12	at	at	ADP
admet-2366	241	13	197.51	197.51	NUM
admet-2366	241	14	°	°	ADP
admet-2366	241	15	c	c	NOUN
admet-2366	241	16	,	,	PUNCT
admet-2366	241	17	within	within	ADP
admet-2366	241	18	the	the	DET
admet-2366	241	19	gefitinib	gefitinib	NOUN
admet-2366	241	20	melting	melt	VERB
admet-2366	241	21	range	range	NOUN
admet-2366	241	22	of	of	ADP
admet-2366	241	23	193	193	NUM
admet-2366	241	24	-	-	SYM
admet-2366	241	25	198	198	NUM
admet-2366	241	26	°	°	NOUN
admet-2366	241	27	c	c	NOUN
admet-2366	241	28	,	,	PUNCT
admet-2366	241	29	with	with	ADP
admet-2366	241	30	a	a	DET
admet-2366	241	31	purity	purity	NOUN
admet-2366	241	32	level	level	NOUN
admet-2366	241	33	of	of	ADP
admet-2366	241	34	99.42	99.42	NUM
admet-2366	241	35	mol	mol	ADP
admet-2366	241	36	%	%	NOUN
admet-2366	241	37	(	(	PUNCT
admet-2366	241	38	figure	figure	NOUN
admet-2366	241	39	3i	3i	NUM
admet-2366	241	40	)	)	PUNCT
admet-2366	241	41	.	.	PUNCT
admet-2366	242	1	the	the	DET
admet-2366	242	2	endothermic	endothermic	PROPN
admet-2366	242	3	peak	peak	NOUN
admet-2366	242	4	of	of	ADP
admet-2366	242	5	the	the	DET
admet-2366	242	6	drug	drug	NOUN
admet-2366	242	7	disappeared	disappear	VERB
admet-2366	242	8	in	in	ADP
admet-2366	242	9	the	the	DET
admet-2366	242	10	thermogram	thermogram	NOUN
admet-2366	242	11	of	of	ADP
admet-2366	242	12	batch	batch	NOUN
admet-2366	242	13	ng13	ng13	PROPN
admet-2366	242	14	(	(	PUNCT
admet-2366	242	15	figure	figure	NOUN
admet-2366	242	16	3ii	3ii	NOUN
admet-2366	242	17	)	)	PUNCT
admet-2366	242	18	.	.	PUNCT
admet-2366	243	1	at	at	ADP
admet-2366	243	2	153.87	153.87	NUM
admet-2366	243	3	°	°	ADP
admet-2366	243	4	c	c	NOUN
admet-2366	243	5	,	,	PUNCT
admet-2366	243	6	a	a	DET
admet-2366	243	7	sharp	sharp	ADJ
admet-2366	243	8	endothermic	endothermic	NOUN
admet-2366	243	9	peak	peak	NOUN
admet-2366	243	10	almost	almost	ADV
admet-2366	243	11	exactly	exactly	ADV
admet-2366	243	12	matches	match	VERB
admet-2366	243	13	the	the	DET
admet-2366	243	14	liquefaction	liquefaction	NOUN
admet-2366	243	15	point	point	NOUN
admet-2366	243	16	of	of	ADP
admet-2366	243	17	cholesterol	cholesterol	NOUN
admet-2366	243	18	.	.	PUNCT
admet-2366	244	1	a	a	DET
admet-2366	244	2	prominent	prominent	ADJ
admet-2366	244	3	endothermic	endothermic	NOUN
admet-2366	244	4	peak	peak	NOUN
admet-2366	244	5	appeared	appear	VERB
admet-2366	244	6	in	in	ADP
admet-2366	244	7	the	the	DET
admet-2366	244	8	case	case	NOUN
admet-2366	244	9	of	of	ADP
admet-2366	244	10	surface	surface	NOUN
admet-2366	244	11	-	-	PUNCT
admet-2366	244	12	adorned	adorn	VERB
admet-2366	244	13	nanoliposomes	nanoliposome	NOUN
admet-2366	244	14	.	.	PUNCT
admet-2366	245	1	the	the	DET
admet-2366	245	2	disappearance	disappearance	NOUN
admet-2366	245	3	of	of	ADP
admet-2366	245	4	the	the	DET
admet-2366	245	5	endothermic	endothermic	ADJ
admet-2366	245	6	peak	peak	NOUN
admet-2366	245	7	of	of	ADP
admet-2366	245	8	the	the	DET
admet-2366	245	9	drug	drug	NOUN
admet-2366	245	10	in	in	ADP
admet-2366	245	11	the	the	DET
admet-2366	245	12	case	case	NOUN
admet-2366	245	13	of	of	ADP
admet-2366	245	14	an	an	DET
admet-2366	245	15	optimized	optimize	VERB
admet-2366	245	16	batch	batch	NOUN
admet-2366	245	17	signifies	signify	VERB
admet-2366	245	18	that	that	SCONJ
admet-2366	245	19	during	during	ADP
admet-2366	245	20	the	the	DET
admet-2366	245	21	preparation	preparation	NOUN
admet-2366	245	22	of	of	ADP
admet-2366	245	23	nanoliposomes	nanoliposome	NOUN
admet-2366	245	24	,	,	PUNCT
admet-2366	245	25	the	the	DET
admet-2366	245	26	drug	drug	NOUN
admet-2366	245	27	may	may	AUX
admet-2366	245	28	disperse	disperse	VERB
admet-2366	245	29	as	as	ADP
admet-2366	245	30	an	an	DET
admet-2366	245	31	amorphous	amorphous	ADJ
admet-2366	245	32	form	form	NOUN
admet-2366	245	33	in	in	ADP
admet-2366	245	34	the	the	DET
admet-2366	245	35	polymeric	polymeric	ADJ
admet-2366	245	36	medium	medium	NOUN
admet-2366	245	37	.	.	PUNCT
admet-2366	246	1	figure	figure	NOUN
admet-2366	246	2	3	3	NUM
admet-2366	246	3	.	.	PUNCT
admet-2366	247	1	overlay	overlay	NOUN
admet-2366	247	2	of	of	ADP
admet-2366	247	3	dsc	dsc	NOUN
admet-2366	247	4	analysis	analysis	NOUN
admet-2366	247	5	of	of	ADP
admet-2366	247	6	gefitinib	gefitinib	NOUN
admet-2366	247	7	,	,	PUNCT
admet-2366	247	8	chitosan	chitosan	NOUN
admet-2366	247	9	,	,	PUNCT
admet-2366	247	10	cholesterol	cholesterol	NOUN
admet-2366	247	11	,	,	PUNCT
admet-2366	247	12	soya	soya	NOUN
admet-2366	247	13	lecithin	lecithin	NOUN
admet-2366	247	14	,	,	PUNCT
admet-2366	247	15	and	and	CCONJ
admet-2366	247	16	uncoated	uncoated	ADJ
admet-2366	247	17	nanoliposomal	nanoliposomal	ADJ
admet-2366	247	18	formulation	formulation	NOUN
admet-2366	247	19	(	(	PUNCT
admet-2366	247	20	i	i	NOUN
admet-2366	247	21	)	)	PUNCT
admet-2366	247	22	,	,	PUNCT
admet-2366	247	23	and	and	CCONJ
admet-2366	247	24	chitosan	chitosan	NOUN
admet-2366	247	25	-	-	PUNCT
admet-2366	247	26	coated	coat	VERB
admet-2366	247	27	optimized	optimize	VERB
admet-2366	247	28	nanoliposomes	nanoliposome	NOUN
admet-2366	247	29	(	(	PUNCT
admet-2366	247	30	formulation	formulation	NOUN
admet-2366	247	31	ng13	ng13	PROPN
admet-2366	247	32	)	)	PUNCT
admet-2366	247	33	(	(	PUNCT
admet-2366	247	34	ii	ii	NOUN
admet-2366	247	35	)	)	PUNCT
admet-2366	247	36	.	.	PUNCT
admet-2366	248	1	fourier	fourier	PROPN
admet-2366	248	2	transforms	transform	VERB
admet-2366	248	3	infrared	infrared	ADJ
admet-2366	248	4	spectrophotometry	spectrophotometry	PROPN
admet-2366	248	5	ftir	ftir	PROPN
admet-2366	248	6	data	data	PROPN
admet-2366	248	7	can	can	AUX
admet-2366	248	8	provide	provide	VERB
admet-2366	248	9	comprehensive	comprehensive	ADJ
admet-2366	248	10	information	information	NOUN
admet-2366	248	11	about	about	ADP
admet-2366	248	12	the	the	DET
admet-2366	248	13	chemical	chemical	NOUN
admet-2366	248	14	identity	identity	NOUN
admet-2366	248	15	,	,	PUNCT
admet-2366	248	16	structure	structure	NOUN
admet-2366	248	17	,	,	PUNCT
admet-2366	248	18	purity	purity	NOUN
admet-2366	248	19	,	,	PUNCT
admet-2366	248	20	and	and	CCONJ
admet-2366	248	21	interactions	interaction	NOUN
admet-2366	248	22	of	of	ADP
admet-2366	248	23	the	the	DET
admet-2366	248	24	sample	sample	NOUN
admet-2366	248	25	being	be	AUX
admet-2366	248	26	analyzed	analyze	VERB
admet-2366	248	27	.	.	PUNCT
admet-2366	249	1	figure	figure	NOUN
admet-2366	249	2	4	4	NUM
admet-2366	249	3	shows	show	VERB
admet-2366	249	4	ftir	ftir	PROPN
admet-2366	249	5	spectra	spectra	PROPN
admet-2366	249	6	of	of	ADP
admet-2366	249	7	cholesterol	cholesterol	NOUN
admet-2366	249	8	(	(	PUNCT
admet-2366	249	9	i	i	NOUN
admet-2366	249	10	)	)	PUNCT
admet-2366	249	11	,	,	PUNCT
admet-2366	249	12	chitosan	chitosan	PROPN
admet-2366	249	13	(	(	PUNCT
admet-2366	249	14	ii	ii	NOUN
admet-2366	249	15	)	)	PUNCT
admet-2366	249	16	,	,	PUNCT
admet-2366	249	17	soya	soya	PROPN
admet-2366	249	18	admet	admet	PROPN
admet-2366	249	19	&	&	CCONJ
admet-2366	249	20	dmpk	dmpk	PROPN
admet-2366	249	21	12(4	12(4	PROPN
admet-2366	249	22	)	)	PUNCT
admet-2366	249	23	(	(	PUNCT
admet-2366	249	24	2024	2024	NUM
admet-2366	249	25	)	)	PUNCT
admet-2366	249	26	657	657	NUM
admet-2366	249	27	-	-	SYM
admet-2366	249	28	677	677	NUM
admet-2366	249	29	optimizing	optimizing	NOUN
admet-2366	249	30	gefitinib	gefitinib	NOUN
admet-2366	249	31	nanoliposomes	nanoliposomes	ADV
admet-2366	249	32	doi	doi	ADV
admet-2366	249	33	:	:	PUNCT
admet-2366	249	34	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	NOUN
admet-2366	249	35	667	667	NUM
admet-2366	249	36	lecithin	lecithin	NOUN
admet-2366	249	37	(	(	PUNCT
admet-2366	249	38	iii	iii	NOUN
admet-2366	249	39	)	)	PUNCT
admet-2366	249	40	,	,	PUNCT
admet-2366	249	41	and	and	CCONJ
admet-2366	249	42	(	(	PUNCT
admet-2366	249	43	iv	iv	X
admet-2366	249	44	)	)	PUNCT
admet-2366	249	45	gefitinib	gefitinib	NOUN
admet-2366	249	46	.	.	PUNCT
admet-2366	250	1	the	the	DET
admet-2366	250	2	overlay	overlay	NOUN
admet-2366	250	3	spectra	spectra	NOUN
admet-2366	250	4	of	of	ADP
admet-2366	250	5	gefitinib	gefitinib	NOUN
admet-2366	250	6	-	-	PUNCT
admet-2366	250	7	loaded	load	VERB
admet-2366	250	8	nanoliposomes	nanoliposome	NOUN
admet-2366	250	9	and	and	CCONJ
admet-2366	250	10	surface	surface	NOUN
admet-2366	250	11	-	-	PUNCT
admet-2366	250	12	adorned	adorn	VERB
admet-2366	250	13	nanoliposomes	nanoliposome	NOUN
admet-2366	250	14	are	be	AUX
admet-2366	250	15	shown	show	VERB
admet-2366	250	16	in	in	ADP
admet-2366	250	17	figure	figure	NOUN
admet-2366	250	18	5	5	NUM
admet-2366	250	19	.	.	PUNCT
admet-2366	251	1	the	the	DET
admet-2366	251	2	ft	ft	PROPN
admet-2366	251	3	-	-	PUNCT
admet-2366	251	4	ir	ir	NOUN
admet-2366	251	5	spectrum	spectrum	NOUN
admet-2366	251	6	of	of	ADP
admet-2366	251	7	gefitinib	gefitinib	NOUN
admet-2366	251	8	illustrated	illustrate	VERB
admet-2366	251	9	the	the	DET
admet-2366	251	10	characteristic	characteristic	ADJ
admet-2366	251	11	peaks	peak	NOUN
admet-2366	251	12	at	at	ADP
admet-2366	251	13	1398.46	1398.46	NUM
admet-2366	251	14	cm-1	cm-1	NOUN
admet-2366	252	1	(	(	PUNCT
admet-2366	252	2	c	c	NOUN
admet-2366	252	3	=	=	NOUN
admet-2366	252	4	n	n	X
admet-2366	252	5	stretching	stretching	NOUN
admet-2366	252	6	)	)	PUNCT
admet-2366	252	7	,	,	PUNCT
admet-2366	252	8	1470.88	1470.88	NUM
admet-2366	252	9	cm-1	cm-1	X
admet-2366	252	10	(	(	PUNCT
admet-2366	252	11	c	c	NOUN
admet-2366	252	12	-	-	PUNCT
admet-2366	252	13	h	h	NOUN
admet-2366	252	14	deformation	deformation	NOUN
admet-2366	252	15	)	)	PUNCT
admet-2366	252	16	,	,	PUNCT
admet-2366	252	17	1623.93	1623.93	NUM
admet-2366	252	18	cm-1	cm-1	X
admet-2366	252	19	(	(	PUNCT
admet-2366	252	20	c	c	X
admet-2366	252	21	=	=	NOUN
admet-2366	252	22	o	o	NOUN
admet-2366	252	23	stretching	stretching	NOUN
admet-2366	252	24	)	)	PUNCT
admet-2366	252	25	,	,	PUNCT
admet-2366	252	26	2852	2852	NUM
admet-2366	252	27	cm-1	cm-1	PART
admet-2366	252	28	(=	(=	PROPN
admet-2366	252	29	ch2	ch2	PROPN
admet-2366	252	30	stretching	stretching	PROPN
admet-2366	252	31	)	)	PUNCT
admet-2366	252	32	,	,	PUNCT
admet-2366	252	33	2941.83	2941.83	NUM
admet-2366	252	34	cm-1	cm-1	X
admet-2366	252	35	(	(	PUNCT
admet-2366	252	36	n	n	CCONJ
admet-2366	252	37	-	-	PUNCT
admet-2366	252	38	ch3	ch3	NOUN
admet-2366	252	39	stretching	stretching	NOUN
admet-2366	252	40	)	)	PUNCT
admet-2366	252	41	,	,	PUNCT
admet-2366	252	42	and	and	CCONJ
admet-2366	252	43	3397.08	3397.08	NUM
admet-2366	252	44	cm-1	cm-1	X
admet-2366	252	45	(	(	PUNCT
admet-2366	252	46	n	n	CCONJ
admet-2366	252	47	-	-	PUNCT
admet-2366	252	48	h	h	NOUN
admet-2366	252	49	stretching	stretching	NOUN
admet-2366	252	50	)	)	PUNCT
admet-2366	252	51	.	.	PUNCT
admet-2366	253	1	the	the	DET
admet-2366	253	2	strong	strong	ADJ
admet-2366	253	3	and	and	CCONJ
admet-2366	253	4	wide	wide	ADJ
admet-2366	253	5	peak	peak	NOUN
admet-2366	253	6	in	in	ADP
admet-2366	253	7	the	the	DET
admet-2366	253	8	range	range	NOUN
admet-2366	253	9	of	of	ADP
admet-2366	253	10	3500	3500	NUM
admet-2366	253	11	-	-	SYM
admet-2366	253	12	3300	3300	NUM
admet-2366	253	13	cm-1	cm-1	NOUN
admet-2366	253	14	corresponds	correspond	NOUN
admet-2366	253	15	to	to	ADP
admet-2366	253	16	n	n	CCONJ
admet-2366	253	17	-	-	PUNCT
admet-2366	253	18	h	h	NOUN
admet-2366	253	19	stretching	stretching	NOUN
admet-2366	253	20	and	and	CCONJ
admet-2366	253	21	hydrogen	hydrogen	NOUN
admet-2366	253	22	-	-	PUNCT
admet-2366	253	23	bonded	bond	VERB
admet-2366	253	24	stretching	stretching	NOUN
admet-2366	253	25	vibrations	vibration	NOUN
admet-2366	253	26	from	from	ADP
admet-2366	253	27	primary	primary	ADJ
admet-2366	253	28	amine	amine	NOUN
admet-2366	253	29	.	.	PUNCT
admet-2366	254	1	the	the	DET
admet-2366	254	2	-ch	-ch	ADV
admet-2366	254	3	stretching	stretching	NOUN
admet-2366	254	4	was	be	AUX
admet-2366	254	5	depicted	depict	VERB
admet-2366	254	6	by	by	ADP
admet-2366	254	7	the	the	DET
admet-2366	254	8	peak	peak	NOUN
admet-2366	254	9	in	in	ADP
admet-2366	254	10	the	the	DET
admet-2366	254	11	range	range	NOUN
admet-2366	254	12	of	of	ADP
admet-2366	254	13	2923.28	2923.28	NUM
admet-2366	254	14	-	-	SYM
admet-2366	254	15	2850.91	2850.91	NUM
admet-2366	254	16	cm-1	cm-1	NOUN
admet-2366	254	17	.	.	PUNCT
admet-2366	255	1	in	in	ADP
admet-2366	255	2	the	the	DET
admet-2366	255	3	chitosan	chitosan	ADJ
admet-2366	255	4	spectra	spectra	NOUN
admet-2366	255	5	(	(	PUNCT
admet-2366	255	6	fig	fig	NOUN
admet-2366	255	7	.	.	PUNCT
admet-2366	255	8	4ii	4ii	ADJ
admet-2366	255	9	)	)	PUNCT
admet-2366	255	10	,	,	PUNCT
admet-2366	255	11	the	the	DET
admet-2366	255	12	broad	broad	ADJ
admet-2366	255	13	peak	peak	NOUN
admet-2366	255	14	in	in	ADP
admet-2366	255	15	the	the	DET
admet-2366	255	16	range	range	NOUN
admet-2366	255	17	of	of	ADP
admet-2366	255	18	1637.39	1637.39	NUM
admet-2366	255	19	1419.23	1419.23	NUM
admet-2366	255	20	cm-1	cm-1	PART
admet-2366	255	21	corresponded	correspond	VERB
admet-2366	255	22	to	to	ADP
admet-2366	255	23	carbonyl	carbonyl	NOUN
admet-2366	255	24	amide	amide	NOUN
admet-2366	255	25	(	(	PUNCT
admet-2366	255	26	amide	amide	NOUN
admet-2366	255	27	i	i	PROPN
admet-2366	255	28	)	)	PUNCT
admet-2366	255	29	.	.	PUNCT
admet-2366	256	1	a	a	DET
admet-2366	256	2	broad	broad	ADJ
admet-2366	256	3	peak	peak	NOUN
admet-2366	256	4	in	in	ADP
admet-2366	256	5	the	the	DET
admet-2366	256	6	1063.51	1063.51	NUM
admet-2366	256	7	-	-	SYM
admet-2366	256	8	1027.67	1027.67	NUM
admet-2366	256	9	cm-1	cm-1	NOUN
admet-2366	256	10	range	range	NOUN
admet-2366	256	11	almost	almost	ADV
admet-2366	256	12	corresponds	correspond	VERB
admet-2366	256	13	to	to	ADP
admet-2366	256	14	the	the	DET
admet-2366	256	15	coc	coc	ADJ
admet-2366	256	16	groups	group	NOUN
admet-2366	256	17	symmetric	symmetric	ADJ
admet-2366	256	18	stretching	stretching	NOUN
admet-2366	256	19	of	of	ADP
admet-2366	256	20	the	the	DET
admet-2366	256	21	chitosan	chitosan	ADJ
admet-2366	256	22	molecule	molecule	NOUN
admet-2366	256	23	,	,	PUNCT
admet-2366	256	24	which	which	PRON
admet-2366	256	25	is	be	AUX
admet-2366	256	26	depicted	depict	VERB
admet-2366	256	27	in	in	ADP
admet-2366	256	28	the	the	DET
admet-2366	256	29	ft	ft	PROPN
admet-2366	256	30	-	-	PUNCT
admet-2366	256	31	ir	ir	NOUN
admet-2366	256	32	spectra	spectra	NOUN
admet-2366	256	33	of	of	ADP
admet-2366	256	34	chitosan	chitosan	NOUN
admet-2366	256	35	-	-	PUNCT
admet-2366	256	36	coated	coat	VERB
admet-2366	256	37	nanoliposomes	nanoliposome	NOUN
admet-2366	256	38	(	(	PUNCT
admet-2366	256	39	fig	fig	NOUN
admet-2366	256	40	.	.	PUNCT
admet-2366	257	1	5ii	5ii	NOUN
admet-2366	257	2	)	)	PUNCT
admet-2366	258	1	but	but	CCONJ
admet-2366	258	2	not	not	PART
admet-2366	258	3	in	in	ADP
admet-2366	258	4	the	the	DET
admet-2366	258	5	spectrum	spectrum	NOUN
admet-2366	258	6	of	of	ADP
admet-2366	258	7	unadorned	unadorned	ADJ
admet-2366	258	8	nanoliposomes	nanoliposome	NOUN
admet-2366	258	9	(	(	PUNCT
admet-2366	258	10	i	i	NOUN
admet-2366	258	11	)	)	PUNCT
admet-2366	258	12	.	.	PUNCT
admet-2366	259	1	figure	figure	NOUN
admet-2366	259	2	5	5	NUM
admet-2366	259	3	demonstrated	demonstrate	VERB
admet-2366	259	4	that	that	SCONJ
admet-2366	259	5	neither	neither	CCONJ
admet-2366	259	6	new	new	ADJ
admet-2366	259	7	peaks	peak	NOUN
admet-2366	259	8	nor	nor	CCONJ
admet-2366	259	9	considerable	considerable	ADJ
admet-2366	259	10	alteration	alteration	NOUN
admet-2366	259	11	of	of	ADP
admet-2366	259	12	functional	functional	ADJ
admet-2366	259	13	peaks	peak	NOUN
admet-2366	259	14	nor	nor	CCONJ
admet-2366	259	15	overlaps	overlap	NOUN
admet-2366	259	16	of	of	ADP
admet-2366	259	17	attribute	attribute	NOUN
admet-2366	259	18	peaks	peak	NOUN
admet-2366	259	19	were	be	AUX
admet-2366	259	20	observed	observe	VERB
admet-2366	259	21	in	in	ADP
admet-2366	259	22	the	the	DET
admet-2366	259	23	optimized	optimize	VERB
admet-2366	259	24	batch	batch	NOUN
admet-2366	259	25	and	and	CCONJ
admet-2366	259	26	surface	surface	NOUN
admet-2366	259	27	-	-	PUNCT
admet-2366	259	28	adorned	adorn	VERB
admet-2366	259	29	nanoliposomes	nanoliposome	NOUN
admet-2366	259	30	compared	compare	VERB
admet-2366	259	31	to	to	ADP
admet-2366	259	32	the	the	DET
admet-2366	259	33	pure	pure	ADJ
admet-2366	259	34	drug	drug	NOUN
admet-2366	259	35	spectrum	spectrum	NOUN
admet-2366	259	36	.	.	PUNCT
admet-2366	260	1	figure	figure	NOUN
admet-2366	260	2	4	4	NUM
admet-2366	260	3	.	.	PUNCT
admet-2366	261	1	overlay	overlay	NOUN
admet-2366	261	2	of	of	ADP
admet-2366	261	3	ftir	ftir	PROPN
admet-2366	261	4	spectra	spectra	PROPN
admet-2366	261	5	of	of	ADP
admet-2366	261	6	cholesterol	cholesterol	NOUN
admet-2366	261	7	(	(	PUNCT
admet-2366	261	8	i	i	NOUN
admet-2366	261	9	)	)	PUNCT
admet-2366	261	10	,	,	PUNCT
admet-2366	261	11	chitosan	chitosan	PROPN
admet-2366	261	12	(	(	PUNCT
admet-2366	261	13	ii	ii	NOUN
admet-2366	261	14	)	)	PUNCT
admet-2366	261	15	,	,	PUNCT
admet-2366	261	16	soya	soya	NOUN
admet-2366	261	17	lecithin	lecithin	PROPN
admet-2366	261	18	(	(	PUNCT
admet-2366	261	19	iii	iii	NOUN
admet-2366	261	20	)	)	PUNCT
admet-2366	261	21	,	,	PUNCT
admet-2366	261	22	and	and	CCONJ
admet-2366	261	23	(	(	PUNCT
admet-2366	261	24	iv	iv	X
admet-2366	261	25	)	)	PUNCT
admet-2366	261	26	gefitinib	gefitinib	NOUN
admet-2366	261	27	.	.	PUNCT
admet-2366	262	1	figure	figure	NOUN
admet-2366	262	2	5	5	NUM
admet-2366	262	3	.	.	PUNCT
admet-2366	263	1	overlay	overlay	NOUN
admet-2366	263	2	of	of	ADP
admet-2366	263	3	ftir	ftir	PROPN
admet-2366	263	4	spectra	spectra	PROPN
admet-2366	263	5	of	of	ADP
admet-2366	263	6	unadorned	unadorned	ADJ
admet-2366	263	7	nanoliposomal	nanoliposomal	ADJ
admet-2366	263	8	formulation	formulation	NOUN
admet-2366	263	9	(	(	PUNCT
admet-2366	263	10	i	i	NOUN
admet-2366	263	11	)	)	PUNCT
admet-2366	263	12	;	;	PUNCT
admet-2366	263	13	coated	coat	VERB
admet-2366	263	14	nanoliposomal	nanoliposomal	ADJ
admet-2366	263	15	formulation	formulation	NOUN
admet-2366	263	16	(	(	PUNCT
admet-2366	263	17	ii	ii	NOUN
admet-2366	263	18	)	)	PUNCT
admet-2366	263	19	.	.	PUNCT
admet-2366	264	1	morphology	morphology	NOUN
admet-2366	264	2	transmission	transmission	NOUN
admet-2366	264	3	electron	electron	NOUN
admet-2366	264	4	micrographs	micrograph	NOUN
admet-2366	264	5	of	of	ADP
admet-2366	264	6	unadorned	unadorned	ADJ
admet-2366	264	7	nanoliposomes	nanoliposome	NOUN
admet-2366	264	8	and	and	CCONJ
admet-2366	264	9	surface	surface	NOUN
admet-2366	264	10	-	-	PUNCT
admet-2366	264	11	adorned	adorn	VERB
admet-2366	264	12	nanoliposomes	nanoliposome	NOUN
admet-2366	264	13	are	be	AUX
admet-2366	264	14	presented	present	VERB
admet-2366	264	15	in	in	ADP
admet-2366	264	16	figure	figure	NOUN
admet-2366	264	17	6	6	NUM
admet-2366	264	18	.	.	PUNCT
admet-2366	265	1	the	the	DET
admet-2366	265	2	results	result	NOUN
admet-2366	265	3	for	for	ADP
admet-2366	265	4	batch	batch	NOUN
admet-2366	265	5	ng13	ng13	PROPN
admet-2366	265	6	showed	show	VERB
admet-2366	265	7	that	that	SCONJ
admet-2366	265	8	the	the	DET
admet-2366	265	9	particles	particle	NOUN
admet-2366	265	10	are	be	AUX
admet-2366	265	11	ellipsoidal	ellipsoidal	ADJ
admet-2366	265	12	or	or	CCONJ
admet-2366	265	13	quasi	quasi	ADJ
admet-2366	265	14	-	-	ADJ
admet-2366	265	15	spherical	spherical	ADJ
admet-2366	266	1	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	ADJ
admet-2366	266	2	s.	s.	PROPN
admet-2366	266	3	rohilla	rohilla	PROPN
admet-2366	266	4	et	et	PROPN
admet-2366	266	5	al	al	PROPN
admet-2366	266	6	.	.	PROPN
admet-2366	266	7	admet	admet	PROPN
admet-2366	266	8	&	&	CCONJ
admet-2366	266	9	dmpk	dmpk	PROPN
admet-2366	266	10	12(4	12(4	PROPN
admet-2366	266	11	)	)	PUNCT
admet-2366	266	12	(	(	PUNCT
admet-2366	266	13	2024	2024	NUM
admet-2366	266	14	)	)	PUNCT
admet-2366	266	15	657	657	NUM
admet-2366	266	16	-	-	SYM
admet-2366	266	17	677	677	NUM
admet-2366	266	18	668	668	NUM
admet-2366	266	19	unilamellar	unilamellar	ADJ
admet-2366	266	20	nanoliposomes	nanoliposome	NOUN
admet-2366	266	21	.	.	PUNCT
admet-2366	267	1	the	the	DET
admet-2366	267	2	coating	coating	NOUN
admet-2366	267	3	of	of	ADP
admet-2366	267	4	chitosan	chitosan	NOUN
admet-2366	267	5	was	be	AUX
admet-2366	267	6	clearly	clearly	ADV
admet-2366	267	7	visible	visible	ADJ
admet-2366	267	8	on	on	ADP
admet-2366	267	9	the	the	DET
admet-2366	267	10	surface	surface	NOUN
admet-2366	267	11	of	of	ADP
admet-2366	267	12	surface	surface	NOUN
admet-2366	267	13	-	-	PUNCT
admet-2366	267	14	adorned	adorn	VERB
admet-2366	267	15	nanoliposomes	nanoliposome	NOUN
admet-2366	267	16	in	in	ADP
admet-2366	267	17	tem	tem	PROPN
admet-2366	267	18	images	image	NOUN
admet-2366	267	19	.	.	PUNCT
admet-2366	268	1	tem	tem	NOUN
admet-2366	268	2	images	image	NOUN
admet-2366	268	3	did	do	AUX
admet-2366	268	4	not	not	PART
admet-2366	268	5	show	show	VERB
admet-2366	268	6	any	any	DET
admet-2366	268	7	physical	physical	ADJ
admet-2366	268	8	aggregation	aggregation	NOUN
admet-2366	268	9	of	of	ADP
admet-2366	268	10	particles	particle	NOUN
admet-2366	268	11	.	.	PUNCT
admet-2366	269	1	figure	figure	VERB
admet-2366	269	2	6	6	NUM
admet-2366	269	3	.	.	PUNCT
admet-2366	269	4	transmission	transmission	NOUN
admet-2366	269	5	electron	electron	NOUN
admet-2366	269	6	micrographs	micrograph	NOUN
admet-2366	269	7	of	of	ADP
admet-2366	269	8	unadorned	unadorned	ADJ
admet-2366	269	9	nanoliposomes	nanoliposome	NOUN
admet-2366	269	10	(	(	PUNCT
admet-2366	269	11	i	i	NOUN
admet-2366	269	12	)	)	PUNCT
admet-2366	269	13	,	,	PUNCT
admet-2366	269	14	surface	surface	NOUN
admet-2366	269	15	adorned	adorn	VERB
admet-2366	269	16	nanoliposomes	nanoliposome	NOUN
admet-2366	269	17	(	(	PUNCT
admet-2366	269	18	ii	ii	NOUN
admet-2366	269	19	)	)	PUNCT
admet-2366	269	20	.	.	PUNCT
admet-2366	270	1	cumulative	cumulative	ADJ
admet-2366	270	2	drug	drug	NOUN
admet-2366	270	3	release	release	NOUN
admet-2366	270	4	and	and	CCONJ
admet-2366	270	5	release	release	VERB
admet-2366	270	6	kinetics	kinetic	NOUN
admet-2366	270	7	after	after	ADP
admet-2366	270	8	24	24	NUM
admet-2366	270	9	h	h	NOUN
admet-2366	270	10	of	of	ADP
admet-2366	270	11	dissolution	dissolution	NOUN
admet-2366	270	12	study	study	NOUN
admet-2366	270	13	,	,	PUNCT
admet-2366	270	14	the	the	DET
admet-2366	270	15	percentage	percentage	NOUN
admet-2366	270	16	cumulative	cumulative	ADJ
admet-2366	270	17	drug	drug	NOUN
admet-2366	270	18	release	release	NOUN
admet-2366	270	19	in	in	ADP
admet-2366	270	20	simulated	simulated	ADJ
admet-2366	270	21	gastrointestinal	gastrointestinal	ADJ
admet-2366	270	22	fluid	fluid	NOUN
admet-2366	270	23	(	(	PUNCT
admet-2366	270	24	ph	ph	NOUN
admet-2366	270	25	1.2	1.2	NUM
admet-2366	270	26	)	)	PUNCT
admet-2366	270	27	,	,	PUNCT
admet-2366	270	28	acetate	acetate	NOUN
admet-2366	270	29	buffer	buffer	NOUN
admet-2366	270	30	(	(	PUNCT
admet-2366	270	31	ph	ph	NOUN
admet-2366	270	32	4.0	4.0	NUM
admet-2366	270	33	)	)	PUNCT
admet-2366	270	34	,	,	PUNCT
admet-2366	270	35	and	and	CCONJ
admet-2366	270	36	simulated	simulate	VERB
admet-2366	270	37	intestinal	intestinal	ADJ
admet-2366	270	38	fluid	fluid	NOUN
admet-2366	270	39	(	(	PUNCT
admet-2366	270	40	ph	ph	NOUN
admet-2366	270	41	6.8	6.8	NUM
admet-2366	270	42	)	)	PUNCT
admet-2366	270	43	was	be	AUX
admet-2366	270	44	82.16±0.65	82.16±0.65	NUM
admet-2366	270	45	,	,	PUNCT
admet-2366	270	46	58.25±0.39	58.25±0.39	NUM
admet-2366	270	47	and	and	CCONJ
admet-2366	270	48	48.72±0.55	48.72±0.55	NUM
admet-2366	270	49	%	%	NOUN
admet-2366	270	50	;	;	PUNCT
admet-2366	270	51	and	and	CCONJ
admet-2366	270	52	78.04±0.3499	78.04±0.3499	NOUN
admet-2366	270	53	,	,	PUNCT
admet-2366	270	54	53.54±0.5916	53.54±0.5916	NUM
admet-2366	270	55	and	and	CCONJ
admet-2366	270	56	45.31±0.9376	45.31±0.9376	NOUN
admet-2366	270	57	%	%	INTJ
admet-2366	270	58	,	,	PUNCT
admet-2366	270	59	respectively	respectively	ADV
admet-2366	270	60	,	,	PUNCT
admet-2366	270	61	from	from	ADP
admet-2366	270	62	uncoated	uncoated	ADJ
admet-2366	270	63	nanoliposomes	nanoliposome	NOUN
admet-2366	270	64	and	and	CCONJ
admet-2366	270	65	chitosan	chitosan	NOUN
admet-2366	270	66	-	-	PUNCT
admet-2366	270	67	coated	coat	VERB
admet-2366	270	68	nanoliposomes	nanoliposome	NOUN
admet-2366	270	69	.	.	PUNCT
admet-2366	271	1	this	this	PRON
admet-2366	271	2	may	may	AUX
admet-2366	271	3	be	be	AUX
admet-2366	271	4	attributed	attribute	VERB
admet-2366	271	5	to	to	ADP
admet-2366	271	6	the	the	DET
admet-2366	271	7	small	small	ADJ
admet-2366	271	8	particle	particle	NOUN
admet-2366	271	9	size	size	NOUN
admet-2366	271	10	of	of	ADP
admet-2366	271	11	prepared	prepared	ADJ
admet-2366	271	12	nanoliposomes	nanoliposome	NOUN
admet-2366	271	13	(	(	PUNCT
admet-2366	271	14	93.2	93.2	NUM
admet-2366	271	15	nm	nm	NOUN
admet-2366	271	16	)	)	PUNCT
admet-2366	271	17	,	,	PUNCT
admet-2366	271	18	which	which	PRON
admet-2366	271	19	provides	provide	VERB
admet-2366	271	20	a	a	DET
admet-2366	271	21	larger	large	ADJ
admet-2366	271	22	effective	effective	ADJ
admet-2366	271	23	surface	surface	NOUN
admet-2366	271	24	area	area	NOUN
admet-2366	271	25	for	for	ADP
admet-2366	271	26	drug	drug	NOUN
admet-2366	271	27	release	release	NOUN
admet-2366	271	28	and	and	CCONJ
admet-2366	271	29	a	a	DET
admet-2366	271	30	short	short	ADJ
admet-2366	271	31	diffusion	diffusion	NOUN
admet-2366	271	32	distance	distance	NOUN
admet-2366	271	33	for	for	ADP
admet-2366	271	34	the	the	DET
admet-2366	271	35	rapid	rapid	ADJ
admet-2366	271	36	release	release	NOUN
admet-2366	271	37	of	of	ADP
admet-2366	271	38	the	the	DET
admet-2366	271	39	entrapped	entrapped	ADJ
admet-2366	271	40	drug	drug	NOUN
admet-2366	271	41	.	.	PUNCT
admet-2366	272	1	ph	ph	PROPN
admet-2366	272	2	influenced	influence	VERB
admet-2366	272	3	the	the	DET
admet-2366	272	4	release	release	NOUN
admet-2366	272	5	behaviour	behaviour	NOUN
admet-2366	272	6	of	of	ADP
admet-2366	272	7	nanoliposomal	nanoliposomal	ADJ
admet-2366	272	8	formulations	formulation	NOUN
admet-2366	272	9	.	.	PUNCT
admet-2366	273	1	the	the	DET
admet-2366	273	2	pure	pure	ADJ
admet-2366	273	3	drug	drug	NOUN
admet-2366	273	4	dispersion	dispersion	NOUN
admet-2366	273	5	showed	show	VERB
admet-2366	273	6	a	a	DET
admet-2366	273	7	maximum	maximum	ADJ
admet-2366	273	8	drug	drug	NOUN
admet-2366	273	9	release	release	NOUN
admet-2366	273	10	of	of	ADP
admet-2366	273	11	25.82±29	25.82±29	NUM
admet-2366	273	12	%	%	NOUN
admet-2366	273	13	in	in	ADP
admet-2366	273	14	acetate	acetate	NOUN
admet-2366	273	15	buffer	buffer	NOUN
admet-2366	273	16	(	(	PUNCT
admet-2366	273	17	ph	ph	NOUN
admet-2366	273	18	4.0	4.0	NUM
admet-2366	273	19	)	)	PUNCT
admet-2366	273	20	after	after	ADP
admet-2366	273	21	24	24	NUM
admet-2366	273	22	h.	h.	NOUN
admet-2366	273	23	the	the	DET
admet-2366	273	24	comparison	comparison	NOUN
admet-2366	273	25	of	of	ADP
admet-2366	273	26	cumulative	cumulative	ADJ
admet-2366	273	27	drug	drug	NOUN
admet-2366	273	28	release	release	NOUN
admet-2366	273	29	between	between	ADP
admet-2366	273	30	pure	pure	ADJ
admet-2366	273	31	drug	drug	NOUN
admet-2366	273	32	solution	solution	NOUN
admet-2366	273	33	,	,	PUNCT
admet-2366	273	34	optimised	optimise	VERB
admet-2366	273	35	uncoated	uncoated	ADJ
admet-2366	273	36	and	and	CCONJ
admet-2366	273	37	surface	surface	NOUN
admet-2366	273	38	-	-	PUNCT
admet-2366	273	39	adorned	adorn	VERB
admet-2366	273	40	nanoliposomal	nanoliposomal	ADJ
admet-2366	273	41	formulations	formulation	NOUN
admet-2366	273	42	is	be	AUX
admet-2366	273	43	shown	show	VERB
admet-2366	273	44	in	in	ADP
admet-2366	273	45	figure	figure	NOUN
admet-2366	273	46	7	7	NUM
admet-2366	273	47	.	.	PUNCT
admet-2366	273	48	figure	figure	VERB
admet-2366	273	49	7	7	NUM
admet-2366	273	50	.	.	PUNCT
admet-2366	273	51	comparison	comparison	NOUN
admet-2366	273	52	of	of	ADP
admet-2366	273	53	in	in	ADP
admet-2366	273	54	vitro	vitro	X
admet-2366	273	55	release	release	NOUN
admet-2366	273	56	of	of	ADP
admet-2366	273	57	drug	drug	NOUN
admet-2366	273	58	from	from	ADP
admet-2366	273	59	pure	pure	ADJ
admet-2366	273	60	drug	drug	NOUN
admet-2366	273	61	dispersion	dispersion	NOUN
admet-2366	273	62	,	,	PUNCT
admet-2366	273	63	optimized	optimize	VERB
admet-2366	273	64	uncoated	uncoated	ADJ
admet-2366	273	65	nanoliposomes	nanoliposome	NOUN
admet-2366	273	66	and	and	CCONJ
admet-2366	273	67	chitosan	chitosan	NOUN
admet-2366	273	68	-	-	PUNCT
admet-2366	273	69	coated	coat	VERB
admet-2366	273	70	nanoliposomes	nanoliposome	NOUN
admet-2366	273	71	(	(	PUNCT
admet-2366	273	72	i	i	NOUN
admet-2366	273	73	)	)	PUNCT
admet-2366	273	74	in	in	ADP
admet-2366	273	75	simulated	simulate	VERB
admet-2366	273	76	gastrointestinal	gastrointestinal	ADJ
admet-2366	273	77	fluid	fluid	NOUN
admet-2366	273	78	,	,	PUNCT
admet-2366	273	79	(	(	PUNCT
admet-2366	273	80	ii	ii	NOUN
admet-2366	273	81	)	)	PUNCT
admet-2366	273	82	in	in	ADP
admet-2366	273	83	acetate	acetate	NOUN
admet-2366	273	84	buffer	buffer	NOUN
admet-2366	273	85	ph	ph	VERB
admet-2366	273	86	4.0	4.0	NUM
admet-2366	273	87	,	,	PUNCT
admet-2366	273	88	and	and	CCONJ
admet-2366	273	89	(	(	PUNCT
admet-2366	273	90	iii	iii	NOUN
admet-2366	273	91	)	)	PUNCT
admet-2366	273	92	in	in	ADP
admet-2366	273	93	simulated	simulated	ADJ
admet-2366	273	94	intestinal	intestinal	ADJ
admet-2366	273	95	fluid	fluid	NOUN
admet-2366	273	96	ph	ph	NOUN
admet-2366	273	97	6.8	6.8	NUM
admet-2366	273	98	.	.	PUNCT
admet-2366	274	1	data	datum	NOUN
admet-2366	274	2	presents	present	NOUN
admet-2366	274	3	mean	mean	VERB
admet-2366	274	4	±	±	NUM
admet-2366	274	5	sd	sd	NOUN
admet-2366	274	6	,	,	PUNCT
admet-2366	274	7	n	n	NOUN
admet-2366	274	8	=	=	SYM
admet-2366	274	9	3	3	X
admet-2366	274	10	.	.	X
admet-2366	274	11	admet	admet	PROPN
admet-2366	274	12	&	&	CCONJ
admet-2366	274	13	dmpk	dmpk	PROPN
admet-2366	274	14	12(4	12(4	PROPN
admet-2366	274	15	)	)	PUNCT
admet-2366	274	16	(	(	PUNCT
admet-2366	274	17	2024	2024	NUM
admet-2366	274	18	)	)	PUNCT
admet-2366	274	19	657	657	NUM
admet-2366	274	20	-	-	SYM
admet-2366	274	21	677	677	NUM
admet-2366	274	22	optimizing	optimizing	NOUN
admet-2366	274	23	gefitinib	gefitinib	NOUN
admet-2366	274	24	nanoliposomes	nanoliposomes	ADV
admet-2366	274	25	doi	doi	ADV
admet-2366	274	26	:	:	PUNCT
admet-2366	274	27	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PROPN
admet-2366	274	28	669	669	NUM
admet-2366	274	29	slow	slow	ADJ
admet-2366	274	30	drug	drug	NOUN
admet-2366	274	31	release	release	NOUN
admet-2366	274	32	was	be	AUX
admet-2366	274	33	recorded	record	VERB
admet-2366	274	34	for	for	ADP
admet-2366	274	35	up	up	ADP
admet-2366	274	36	to	to	PART
admet-2366	274	37	5	5	NUM
admet-2366	274	38	hours	hour	NOUN
admet-2366	274	39	in	in	ADP
admet-2366	274	40	the	the	DET
admet-2366	274	41	dissolution	dissolution	NOUN
admet-2366	274	42	study	study	NOUN
admet-2366	274	43	.	.	PUNCT
admet-2366	275	1	after	after	ADP
admet-2366	275	2	hydrating	hydrate	VERB
admet-2366	275	3	the	the	DET
admet-2366	275	4	polymer	polymer	NOUN
admet-2366	275	5	,	,	PUNCT
admet-2366	275	6	nanoliposomes	nanoliposome	NOUN
admet-2366	275	7	released	release	VERB
admet-2366	275	8	the	the	DET
admet-2366	275	9	drug	drug	NOUN
admet-2366	275	10	following	follow	VERB
admet-2366	275	11	a	a	DET
admet-2366	275	12	first	first	ADJ
admet-2366	275	13	-	-	PUNCT
admet-2366	275	14	order	order	NOUN
admet-2366	275	15	drug	drug	NOUN
admet-2366	275	16	release	release	NOUN
admet-2366	275	17	pattern	pattern	NOUN
admet-2366	275	18	.	.	PUNCT
admet-2366	276	1	the	the	DET
admet-2366	276	2	drug	drug	NOUN
admet-2366	276	3	was	be	AUX
admet-2366	276	4	released	release	VERB
admet-2366	276	5	more	more	ADV
admet-2366	276	6	consistently	consistently	ADV
admet-2366	276	7	from	from	ADP
admet-2366	276	8	the	the	DET
admet-2366	276	9	surface	surface	NOUN
admet-2366	276	10	-	-	PUNCT
admet-2366	276	11	adorned	adorn	VERB
admet-2366	276	12	formulations	formulation	NOUN
admet-2366	276	13	than	than	ADP
admet-2366	276	14	optimised	optimise	VERB
admet-2366	276	15	uncoated	uncoated	ADJ
admet-2366	276	16	nanoliposomal	nanoliposomal	ADJ
admet-2366	276	17	formulations	formulation	NOUN
admet-2366	276	18	.	.	PUNCT
admet-2366	277	1	the	the	DET
admet-2366	277	2	values	value	NOUN
admet-2366	277	3	of	of	ADP
admet-2366	277	4	correlation	correlation	NOUN
admet-2366	277	5	coefficient	coefficient	NOUN
admet-2366	277	6	obtained	obtain	VERB
admet-2366	277	7	for	for	ADP
admet-2366	277	8	zero	zero	NUM
admet-2366	277	9	order	order	NOUN
admet-2366	277	10	,	,	PUNCT
admet-2366	277	11	first	first	ADJ
admet-2366	277	12	order	order	NOUN
admet-2366	277	13	,	,	PUNCT
admet-2366	277	14	higuchi	higuchi	PROPN
admet-2366	277	15	’s	’s	PART
admet-2366	277	16	release	release	NOUN
admet-2366	277	17	model	model	NOUN
admet-2366	277	18	,	,	PUNCT
admet-2366	277	19	and	and	CCONJ
admet-2366	277	20	korsemeyer	korsemeyer	PROPN
admet-2366	277	21	peppas	peppas	PROPN
admet-2366	277	22	’s	’s	PART
admet-2366	277	23	model	model	NOUN
admet-2366	277	24	were	be	AUX
admet-2366	277	25	found	find	VERB
admet-2366	277	26	to	to	PART
admet-2366	277	27	be	be	AUX
admet-2366	277	28	0.924	0.924	NUM
admet-2366	277	29	,	,	PUNCT
admet-2366	277	30	0.981	0.981	NUM
admet-2366	277	31	,	,	PUNCT
admet-2366	277	32	0.980	0.980	NUM
admet-2366	277	33	,	,	PUNCT
admet-2366	277	34	and	and	CCONJ
admet-2366	277	35	0.968	0.968	NUM
admet-2366	277	36	,	,	PUNCT
admet-2366	277	37	respectively	respectively	ADV
admet-2366	277	38	,	,	PUNCT
admet-2366	277	39	in	in	ADP
admet-2366	277	40	uncoated	uncoated	ADJ
admet-2366	277	41	nanoliposomes	nanoliposome	NOUN
admet-2366	277	42	,	,	PUNCT
admet-2366	277	43	whereas	whereas	SCONJ
admet-2366	277	44	in	in	ADP
admet-2366	277	45	surface	surface	NOUN
admet-2366	277	46	-	-	PUNCT
admet-2366	277	47	adorned	adorn	VERB
admet-2366	277	48	nanoliposomes	nanoliposome	NOUN
admet-2366	277	49	,	,	PUNCT
admet-2366	277	50	the	the	DET
admet-2366	277	51	values	value	NOUN
admet-2366	277	52	of	of	ADP
admet-2366	277	53	correlation	correlation	NOUN
admet-2366	277	54	coefficient	coefficient	NOUN
admet-2366	277	55	were	be	AUX
admet-2366	277	56	found	find	VERB
admet-2366	277	57	to	to	PART
admet-2366	277	58	be	be	AUX
admet-2366	277	59	0.974	0.974	NUM
admet-2366	277	60	,	,	PUNCT
admet-2366	277	61	0.993	0.993	NUM
admet-2366	277	62	,	,	PUNCT
admet-2366	277	63	0.978	0.978	NUM
admet-2366	277	64	,	,	PUNCT
admet-2366	277	65	and	and	CCONJ
admet-2366	277	66	0.953	0.953	NUM
admet-2366	277	67	,	,	PUNCT
admet-2366	277	68	respectively	respectively	ADV
admet-2366	277	69	,	,	PUNCT
admet-2366	277	70	for	for	ADP
admet-2366	277	71	zero	zero	NUM
admet-2366	277	72	order	order	NOUN
admet-2366	277	73	,	,	PUNCT
admet-2366	277	74	first	first	ADJ
admet-2366	277	75	order	order	NOUN
admet-2366	277	76	,	,	PUNCT
admet-2366	277	77	higuchi	higuchi	PROPN
admet-2366	277	78	’s	’s	PART
admet-2366	277	79	release	release	NOUN
admet-2366	277	80	model	model	NOUN
admet-2366	277	81	,	,	PUNCT
admet-2366	277	82	and	and	CCONJ
admet-2366	277	83	korsemeyer	korsemeyer	PROPN
admet-2366	277	84	peppas	peppas	PROPN
admet-2366	277	85	’s	’s	PART
admet-2366	277	86	model	model	NOUN
admet-2366	277	87	.	.	PUNCT
admet-2366	278	1	the	the	DET
admet-2366	278	2	elevated	elevated	ADJ
admet-2366	278	3	correlation	correlation	NOUN
admet-2366	278	4	coefficients	coefficient	NOUN
admet-2366	278	5	in	in	ADP
admet-2366	278	6	first	first	ADJ
admet-2366	278	7	-	-	PUNCT
admet-2366	278	8	order	order	NOUN
admet-2366	278	9	release	release	NOUN
admet-2366	278	10	kinetics	kinetic	NOUN
admet-2366	278	11	for	for	ADP
admet-2366	278	12	both	both	CCONJ
admet-2366	278	13	uncoated	uncoated	ADJ
admet-2366	278	14	and	and	CCONJ
admet-2366	278	15	surface	surface	NOUN
admet-2366	278	16	-	-	PUNCT
admet-2366	278	17	adorned	adorn	VERB
admet-2366	278	18	nanoliposomes	nanoliposome	NOUN
admet-2366	278	19	,	,	PUNCT
admet-2366	278	20	such	such	ADJ
admet-2366	278	21	as	as	ADP
admet-2366	278	22	0.981	0.981	NUM
admet-2366	278	23	and	and	CCONJ
admet-2366	278	24	0.993	0.993	NUM
admet-2366	278	25	;	;	PUNCT
admet-2366	278	26	0.905	0.905	NUM
admet-2366	278	27	and	and	CCONJ
admet-2366	278	28	0.965	0.965	NUM
admet-2366	278	29	;	;	PUNCT
admet-2366	278	30	and	and	CCONJ
admet-2366	278	31	0.958	0.958	NUM
admet-2366	278	32	and	and	CCONJ
admet-2366	278	33	0.959	0.959	NUM
admet-2366	278	34	in	in	ADP
admet-2366	278	35	simulated	simulated	ADJ
admet-2366	278	36	gastrointestinal	gastrointestinal	ADJ
admet-2366	278	37	fluid	fluid	NOUN
admet-2366	278	38	(	(	PUNCT
admet-2366	278	39	acetate	acetate	NOUN
admet-2366	278	40	buffer	buffer	NOUN
admet-2366	278	41	ph	ph	VERB
admet-2366	278	42	4.0	4.0	NUM
admet-2366	278	43	)	)	PUNCT
admet-2366	278	44	and	and	CCONJ
admet-2366	278	45	simulated	simulate	VERB
admet-2366	278	46	intestinal	intestinal	ADJ
admet-2366	278	47	ph	ph	ADJ
admet-2366	278	48	6.8	6.8	NUM
admet-2366	278	49	,	,	PUNCT
admet-2366	278	50	demonstrated	demonstrate	VERB
admet-2366	278	51	that	that	SCONJ
admet-2366	278	52	drug	drug	NOUN
admet-2366	278	53	release	release	NOUN
admet-2366	278	54	followed	follow	VERB
admet-2366	278	55	first	first	ADJ
admet-2366	278	56	-	-	PUNCT
admet-2366	278	57	order	order	NOUN
admet-2366	278	58	release	release	NOUN
admet-2366	278	59	kinetics	kinetic	NOUN
admet-2366	278	60	.	.	PUNCT
admet-2366	279	1	for	for	ADP
admet-2366	279	2	korsmeyer	korsmeyer	NOUN
admet-2366	279	3	-	-	PUNCT
admet-2366	279	4	peppas	peppas	PROPN
admet-2366	279	5	’	'	PUNCT
admet-2366	279	6	model	model	NOUN
admet-2366	279	7	,	,	PUNCT
admet-2366	279	8	the	the	DET
admet-2366	279	9	n	n	PRON
admet-2366	279	10	values	value	NOUN
admet-2366	279	11	were	be	AUX
admet-2366	279	12	found	find	VERB
admet-2366	279	13	to	to	PART
admet-2366	279	14	be	be	AUX
admet-2366	279	15	0.395	0.395	NUM
admet-2366	279	16	,	,	PUNCT
admet-2366	279	17	0.327	0.327	NUM
admet-2366	279	18	and	and	CCONJ
admet-2366	279	19	0.292	0.292	NUM
admet-2366	279	20	in	in	ADP
admet-2366	279	21	simulated	simulated	ADJ
admet-2366	279	22	gastrointestinal	gastrointestinal	ADJ
admet-2366	279	23	fluid	fluid	NOUN
admet-2366	279	24	,	,	PUNCT
admet-2366	279	25	in	in	ADP
admet-2366	279	26	acetate	acetate	NOUN
admet-2366	279	27	buffer	buffer	NOUN
admet-2366	279	28	(	(	PUNCT
admet-2366	279	29	ph	ph	NOUN
admet-2366	279	30	4.0	4.0	NUM
admet-2366	279	31	)	)	PUNCT
admet-2366	279	32	,	,	PUNCT
admet-2366	279	33	and	and	CCONJ
admet-2366	279	34	simulated	simulate	VERB
admet-2366	279	35	intestinal	intestinal	ADJ
admet-2366	279	36	fluid	fluid	NOUN
admet-2366	279	37	(	(	PUNCT
admet-2366	279	38	ph	ph	NOUN
admet-2366	279	39	6.8	6.8	NUM
admet-2366	279	40	)	)	PUNCT
admet-2366	279	41	,	,	PUNCT
admet-2366	279	42	respectively	respectively	ADV
admet-2366	279	43	,	,	PUNCT
admet-2366	279	44	for	for	ADP
admet-2366	279	45	uncoated	uncoated	ADJ
admet-2366	279	46	nanoliposomes	nanoliposome	NOUN
admet-2366	279	47	.	.	PUNCT
admet-2366	280	1	the	the	DET
admet-2366	280	2	n	n	PRON
admet-2366	280	3	values	value	NOUN
admet-2366	280	4	were	be	AUX
admet-2366	280	5	0.435	0.435	NUM
admet-2366	280	6	,	,	PUNCT
admet-2366	280	7	0.419	0.419	NUM
admet-2366	280	8	,	,	PUNCT
admet-2366	280	9	and	and	CCONJ
admet-2366	280	10	0.426	0.426	NUM
admet-2366	280	11	in	in	ADP
admet-2366	280	12	simulated	simulated	ADJ
admet-2366	280	13	gastrointestinal	gastrointestinal	ADJ
admet-2366	280	14	fluid	fluid	NOUN
admet-2366	280	15	,	,	PUNCT
admet-2366	280	16	acetate	acetate	NOUN
admet-2366	280	17	buffer	buffer	NOUN
admet-2366	280	18	ph	ph	VERB
admet-2366	280	19	4.0	4.0	NUM
admet-2366	280	20	,	,	PUNCT
admet-2366	280	21	and	and	CCONJ
admet-2366	280	22	simulated	simulate	VERB
admet-2366	280	23	intestinal	intestinal	ADJ
admet-2366	280	24	fluid	fluid	NOUN
admet-2366	280	25	ph	ph	NOUN
admet-2366	280	26	6.8	6.8	NUM
admet-2366	280	27	for	for	ADP
admet-2366	280	28	surface	surface	NOUN
admet-2366	280	29	-	-	PUNCT
admet-2366	280	30	adorned	adorn	VERB
admet-2366	280	31	nanoliposomes	nanoliposome	NOUN
admet-2366	280	32	,	,	PUNCT
admet-2366	280	33	respectively	respectively	ADV
admet-2366	280	34	.	.	PUNCT
admet-2366	281	1	cytotoxicity	cytotoxicity	NOUN
admet-2366	281	2	studies	study	NOUN
admet-2366	281	3	figure	figure	VERB
admet-2366	281	4	8	8	NUM
admet-2366	281	5	depicts	depict	VERB
admet-2366	281	6	the	the	DET
admet-2366	281	7	half	half	ADJ
admet-2366	281	8	-	-	PUNCT
admet-2366	281	9	inhibitory	inhibitory	ADJ
admet-2366	281	10	concentrations	concentration	NOUN
admet-2366	281	11	of	of	ADP
admet-2366	281	12	free	free	ADJ
admet-2366	281	13	gefitinib	gefitinib	NOUN
admet-2366	281	14	and	and	CCONJ
admet-2366	281	15	uncoated	uncoated	ADJ
admet-2366	281	16	and	and	CCONJ
admet-2366	281	17	surface	surface	NOUN
admet-2366	281	18	-	-	PUNCT
admet-2366	281	19	adorned	adorn	VERB
admet-2366	281	20	nanoliposomes	nanoliposome	NOUN
admet-2366	281	21	in	in	ADP
admet-2366	281	22	h1299	h1299	NOUN
admet-2366	281	23	and	and	CCONJ
admet-2366	281	24	a549	a549	PROPN
admet-2366	281	25	cells	cell	NOUN
admet-2366	281	26	.	.	PUNCT
admet-2366	282	1	after	after	ADP
admet-2366	282	2	incubation	incubation	NOUN
admet-2366	282	3	,	,	PUNCT
admet-2366	282	4	the	the	DET
admet-2366	282	5	values	value	NOUN
admet-2366	282	6	of	of	ADP
admet-2366	282	7	half	half	NOUN
admet-2366	282	8	inhibitory	inhibitory	ADJ
admet-2366	282	9	concentration	concentration	NOUN
admet-2366	282	10	for	for	ADP
admet-2366	282	11	free	free	ADJ
admet-2366	282	12	gefitinib	gefitinib	NOUN
admet-2366	282	13	were	be	AUX
admet-2366	282	14	1.17±0.8	1.17±0.8	NUM
admet-2366	282	15	and	and	CCONJ
admet-2366	282	16	1.96±0.76	1.96±0.76	NUM
admet-2366	282	17	μm	μm	NUM
admet-2366	282	18	,	,	PUNCT
admet-2366	282	19	respectively	respectively	ADV
admet-2366	282	20	,	,	PUNCT
admet-2366	282	21	in	in	ADP
admet-2366	282	22	a549	a549	PROPN
admet-2366	282	23	and	and	CCONJ
admet-2366	283	1	h1299	h1299	NOUN
admet-2366	283	2	cells	cell	NOUN
admet-2366	283	3	.	.	PUNCT
admet-2366	284	1	in	in	ADP
admet-2366	284	2	contrast	contrast	NOUN
admet-2366	284	3	,	,	PUNCT
admet-2366	284	4	for	for	ADP
admet-2366	284	5	uncoated	uncoated	ADJ
admet-2366	284	6	and	and	CCONJ
admet-2366	284	7	surface	surface	NOUN
admet-2366	284	8	adorned	adorn	VERB
admet-2366	284	9	nanoliposomes	nanoliposome	NOUN
admet-2366	284	10	in	in	ADP
admet-2366	284	11	a549	a549	PROPN
admet-2366	284	12	and	and	CCONJ
admet-2366	285	1	h1299	h1299	NUM
admet-2366	285	2	cells	cell	NOUN
admet-2366	285	3	,	,	PUNCT
admet-2366	285	4	the	the	DET
admet-2366	285	5	values	value	NOUN
admet-2366	285	6	were	be	AUX
admet-2366	285	7	found	find	VERB
admet-2366	285	8	to	to	PART
admet-2366	285	9	be	be	AUX
admet-2366	285	10	7.03±0.85	7.03±0.85	NUM
admet-2366	285	11	,	,	PUNCT
admet-2366	285	12	7.74±0.75	7.74±0.75	PROPN
admet-2366	285	13	and	and	CCONJ
admet-2366	285	14	7.31±0.98	7.31±0.98	NUM
admet-2366	285	15	,	,	PUNCT
admet-2366	285	16	8.89±0.97	8.89±0.97	NOUN
admet-2366	285	17	μm	μm	NUM
admet-2366	285	18	,	,	PUNCT
admet-2366	285	19	respectively	respectively	ADV
admet-2366	285	20	.	.	PUNCT
admet-2366	286	1	chitosan	chitosan	NOUN
admet-2366	286	2	-	-	PUNCT
admet-2366	286	3	coated	coat	VERB
admet-2366	286	4	nanoliposomes	nanoliposome	NOUN
admet-2366	286	5	,	,	PUNCT
admet-2366	286	6	on	on	ADP
admet-2366	286	7	the	the	DET
admet-2366	286	8	other	other	ADJ
admet-2366	286	9	hand	hand	NOUN
admet-2366	286	10	,	,	PUNCT
admet-2366	286	11	had	have	VERB
admet-2366	286	12	a	a	DET
admet-2366	286	13	slightly	slightly	ADV
admet-2366	286	14	higher	high	ADJ
admet-2366	286	15	inhibitory	inhibitory	ADJ
admet-2366	286	16	potential	potential	NOUN
admet-2366	286	17	than	than	ADP
admet-2366	286	18	uncoated	uncoated	ADJ
admet-2366	286	19	formulations	formulation	NOUN
admet-2366	286	20	.	.	PUNCT
admet-2366	287	1	the	the	DET
admet-2366	287	2	values	value	NOUN
admet-2366	287	3	of	of	ADP
admet-2366	287	4	half	half	NOUN
admet-2366	287	5	inhibitory	inhibitory	ADJ
admet-2366	287	6	concentration	concentration	NOUN
admet-2366	287	7	for	for	ADP
admet-2366	287	8	chitosan	chitosan	NOUN
admet-2366	287	9	-	-	PUNCT
admet-2366	287	10	coated	coat	VERB
admet-2366	287	11	nanoliposomes	nanoliposome	NOUN
admet-2366	287	12	in	in	ADP
admet-2366	287	13	a549	a549	PROPN
admet-2366	287	14	and	and	CCONJ
admet-2366	287	15	h1299	h1299	NUM
admet-2366	287	16	cells	cell	NOUN
admet-2366	287	17	were	be	AUX
admet-2366	287	18	found	find	VERB
admet-2366	287	19	to	to	PART
admet-2366	287	20	be	be	AUX
admet-2366	287	21	7.74±0.75	7.74±0.75	PROPN
admet-2366	287	22	,	,	PUNCT
admet-2366	287	23	8.89±0.97	8.89±0.97	NOUN
admet-2366	287	24	μm	μm	NUM
admet-2366	287	25	,	,	PUNCT
admet-2366	287	26	respectively	respectively	ADV
admet-2366	287	27	.	.	PUNCT
admet-2366	288	1	in	in	ADP
admet-2366	288	2	the	the	DET
admet-2366	288	3	current	current	ADJ
admet-2366	288	4	study	study	NOUN
admet-2366	288	5	,	,	PUNCT
admet-2366	288	6	the	the	DET
admet-2366	288	7	results	result	NOUN
admet-2366	288	8	showed	show	VERB
admet-2366	288	9	that	that	SCONJ
admet-2366	288	10	coated	coated	ADJ
admet-2366	288	11	formulations	formulation	NOUN
admet-2366	288	12	(	(	PUNCT
admet-2366	288	13	23.7±0.03	23.7±0.03	NUM
admet-2366	288	14	mv	mv	NOUN
admet-2366	288	15	)	)	PUNCT
admet-2366	288	16	had	have	VERB
admet-2366	288	17	a	a	DET
admet-2366	288	18	higher	high	ADJ
admet-2366	288	19	zeta	zeta	NOUN
admet-2366	288	20	potential	potential	NOUN
admet-2366	288	21	than	than	ADP
admet-2366	288	22	unadorned	unadorned	ADJ
admet-2366	288	23	formulations	formulation	NOUN
admet-2366	288	24	(	(	PUNCT
admet-2366	288	25	-6.51±0.03	-6.51±0.03	NOUN
admet-2366	288	26	mv	mv	NOUN
admet-2366	288	27	)	)	PUNCT
admet-2366	288	28	.	.	PUNCT
admet-2366	289	1	figure	figure	VERB
admet-2366	289	2	8	8	NUM
admet-2366	289	3	.	.	PUNCT
admet-2366	290	1	ic50	ic50	PROPN
admet-2366	290	2	value	value	NOUN
admet-2366	290	3	of	of	ADP
admet-2366	290	4	pure	pure	ADJ
admet-2366	290	5	gefitinib	gefitinib	NOUN
admet-2366	290	6	,	,	PUNCT
admet-2366	290	7	simple	simple	ADJ
admet-2366	290	8	nanoliposomes	nanoliposome	NOUN
admet-2366	290	9	(	(	PUNCT
admet-2366	290	10	uncoated	uncoated	ADJ
admet-2366	290	11	)	)	PUNCT
admet-2366	290	12	,	,	PUNCT
admet-2366	290	13	and	and	CCONJ
admet-2366	290	14	surface	surface	NOUN
admet-2366	290	15	-	-	PUNCT
admet-2366	290	16	adorned	adorn	VERB
admet-2366	290	17	nanoliposomes	nanoliposome	NOUN
admet-2366	290	18	.	.	PUNCT
admet-2366	291	1	stability	stability	NOUN
admet-2366	291	2	studies	study	VERB
admet-2366	291	3	the	the	DET
admet-2366	291	4	results	result	NOUN
admet-2366	291	5	of	of	ADP
admet-2366	291	6	the	the	DET
admet-2366	291	7	stability	stability	NOUN
admet-2366	291	8	study	study	NOUN
admet-2366	291	9	demonstrated	demonstrate	VERB
admet-2366	291	10	that	that	SCONJ
admet-2366	291	11	4	4	NUM
admet-2366	291	12	°	°	SYM
admet-2366	291	13	c	c	NOUN
admet-2366	291	14	was	be	AUX
admet-2366	291	15	the	the	DET
admet-2366	291	16	optimum	optimum	ADJ
admet-2366	291	17	temperature	temperature	NOUN
admet-2366	291	18	to	to	PART
admet-2366	291	19	retain	retain	VERB
admet-2366	291	20	the	the	DET
admet-2366	291	21	chemical	chemical	NOUN
admet-2366	291	22	and	and	CCONJ
admet-2366	291	23	physical	physical	ADJ
admet-2366	291	24	stability	stability	NOUN
admet-2366	291	25	of	of	ADP
admet-2366	291	26	formulated	formulated	ADJ
admet-2366	291	27	vesicles	vesicle	NOUN
admet-2366	291	28	for	for	ADP
admet-2366	291	29	6	6	NUM
admet-2366	291	30	months	month	NOUN
admet-2366	291	31	.	.	PUNCT
admet-2366	292	1	while	while	SCONJ
admet-2366	292	2	conducting	conduct	VERB
admet-2366	292	3	the	the	DET
admet-2366	292	4	stability	stability	NOUN
admet-2366	292	5	study	study	NOUN
admet-2366	292	6	,	,	PUNCT
admet-2366	292	7	the	the	DET
admet-2366	292	8	samples	sample	NOUN
admet-2366	292	9	kept	keep	VERB
admet-2366	292	10	at	at	ADP
admet-2366	292	11	25	25	NUM
admet-2366	292	12	and	and	CCONJ
admet-2366	292	13	45	45	NUM
admet-2366	292	14	°	°	NOUN
admet-2366	292	15	c	c	NOUN
admet-2366	292	16	showed	show	VERB
admet-2366	292	17	many	many	ADJ
admet-2366	292	18	alterations	alteration	NOUN
admet-2366	292	19	in	in	ADP
admet-2366	292	20	encapsulation	encapsulation	NOUN
admet-2366	292	21	efficiency	efficiency	NOUN
admet-2366	292	22	,	,	PUNCT
admet-2366	292	23	particle	particle	NOUN
admet-2366	292	24	size	size	NOUN
admet-2366	292	25	,	,	PUNCT
admet-2366	292	26	and	and	CCONJ
admet-2366	292	27	physical	physical	ADJ
admet-2366	292	28	appearance	appearance	NOUN
admet-2366	292	29	,	,	PUNCT
admet-2366	292	30	but	but	CCONJ
admet-2366	292	31	the	the	DET
admet-2366	292	32	samples	sample	NOUN
admet-2366	292	33	kept	keep	VERB
admet-2366	292	34	at	at	ADP
admet-2366	292	35	4	4	NUM
admet-2366	292	36	°	°	NOUN
admet-2366	292	37	c	c	NOUN
admet-2366	292	38	remained	remain	VERB
admet-2366	292	39	stable	stable	ADJ
admet-2366	292	40	.	.	PUNCT
admet-2366	293	1	a	a	DET
admet-2366	293	2	noteworthy	noteworthy	ADJ
admet-2366	293	3	decline	decline	NOUN
admet-2366	293	4	in	in	ADP
admet-2366	293	5	the	the	DET
admet-2366	293	6	entrapment	entrapment	ADJ
admet-2366	293	7	efficacy	efficacy	NOUN
admet-2366	293	8	was	be	AUX
admet-2366	293	9	estimated	estimate	VERB
admet-2366	293	10	,	,	PUNCT
admet-2366	293	11	which	which	PRON
admet-2366	293	12	depicts	depict	VERB
admet-2366	293	13	a	a	DET
admet-2366	293	14	considerable	considerable	ADJ
admet-2366	293	15	escape	escape	NOUN
admet-2366	293	16	of	of	ADP
admet-2366	293	17	the	the	DET
admet-2366	293	18	drug	drug	NOUN
admet-2366	293	19	from	from	ADP
admet-2366	293	20	the	the	DET
admet-2366	293	21	preparations	preparation	NOUN
admet-2366	293	22	over	over	ADP
admet-2366	293	23	time	time	NOUN
admet-2366	293	24	.	.	PUNCT
admet-2366	294	1	the	the	DET
admet-2366	294	2	mean	mean	ADJ
admet-2366	294	3	particle	particle	NOUN
admet-2366	294	4	size	size	NOUN
admet-2366	294	5	of	of	ADP
admet-2366	294	6	preparations	preparation	NOUN
admet-2366	294	7	was	be	AUX
admet-2366	294	8	also	also	ADV
admet-2366	294	9	estimated	estimate	VERB
admet-2366	294	10	as	as	ADP
admet-2366	294	11	a	a	DET
admet-2366	294	12	function	function	NOUN
admet-2366	294	13	of	of	ADP
admet-2366	294	14	time	time	NOUN
admet-2366	294	15	and	and	CCONJ
admet-2366	294	16	temperature	temperature	NOUN
admet-2366	294	17	.	.	PUNCT
admet-2366	295	1	entrapment	entrapment	ADJ
admet-2366	295	2	efficacy	efficacy	NOUN
admet-2366	295	3	ic	ic	PROPN
admet-2366	295	4	50	50	NUM
admet-2366	295	5	/	/	SYM
admet-2366	295	6			NOUN
admet-2366	295	7	m	m	VERB
admet-2366	295	8	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	ADJ
admet-2366	295	9	s.	s.	PROPN
admet-2366	295	10	rohilla	rohilla	PROPN
admet-2366	295	11	et	et	PROPN
admet-2366	295	12	al	al	PROPN
admet-2366	295	13	.	.	PROPN
admet-2366	295	14	admet	admet	PROPN
admet-2366	295	15	&	&	CCONJ
admet-2366	295	16	dmpk	dmpk	PROPN
admet-2366	295	17	12(4	12(4	PROPN
admet-2366	295	18	)	)	PUNCT
admet-2366	295	19	(	(	PUNCT
admet-2366	295	20	2024	2024	NUM
admet-2366	295	21	)	)	PUNCT
admet-2366	295	22	657	657	NUM
admet-2366	295	23	-	-	SYM
admet-2366	295	24	677	677	NUM
admet-2366	295	25	670	670	NUM
admet-2366	295	26	of	of	ADP
admet-2366	295	27	the	the	DET
admet-2366	295	28	nanovesicles	nanovesicle	NOUN
admet-2366	295	29	kept	keep	VERB
admet-2366	295	30	at	at	ADP
admet-2366	295	31	4	4	NUM
admet-2366	295	32	°	°	NOUN
admet-2366	295	33	c	c	NOUN
admet-2366	295	34	decreased	decrease	VERB
admet-2366	295	35	by	by	ADP
admet-2366	295	36	9	9	NUM
admet-2366	295	37	,	,	PUNCT
admet-2366	295	38	19	19	NUM
admet-2366	295	39	,	,	PUNCT
admet-2366	295	40	32	32	NUM
admet-2366	295	41	,	,	PUNCT
admet-2366	295	42	and	and	CCONJ
admet-2366	295	43	40	40	NUM
admet-2366	295	44	%	%	NOUN
admet-2366	295	45	,	,	PUNCT
admet-2366	295	46	whereas	whereas	SCONJ
admet-2366	295	47	those	those	PRON
admet-2366	295	48	kept	keep	VERB
admet-2366	295	49	at	at	ADP
admet-2366	295	50	25	25	NUM
admet-2366	295	51	°	°	NOUN
admet-2366	295	52	c	c	NOUN
admet-2366	295	53	decreased	decrease	VERB
admet-2366	295	54	by	by	ADP
admet-2366	295	55	16	16	NUM
admet-2366	295	56	,	,	PUNCT
admet-2366	295	57	34	34	NUM
admet-2366	295	58	,	,	PUNCT
admet-2366	295	59	60	60	NUM
admet-2366	295	60	,	,	PUNCT
admet-2366	295	61	and	and	CCONJ
admet-2366	295	62	87	87	NUM
admet-2366	295	63	%	%	NOUN
admet-2366	295	64	,	,	PUNCT
admet-2366	295	65	while	while	SCONJ
admet-2366	295	66	those	those	PRON
admet-2366	295	67	kept	keep	VERB
admet-2366	295	68	at	at	ADP
admet-2366	295	69	45	45	NUM
admet-2366	295	70	°	°	NOUN
admet-2366	295	71	c	c	NOUN
admet-2366	295	72	decreased	decrease	VERB
admet-2366	295	73	by	by	ADP
admet-2366	295	74	43	43	NUM
admet-2366	295	75	,	,	PUNCT
admet-2366	295	76	66	66	NUM
admet-2366	295	77	,	,	PUNCT
admet-2366	295	78	81	81	NUM
admet-2366	295	79	,	,	PUNCT
admet-2366	295	80	and	and	CCONJ
admet-2366	295	81	94	94	NUM
admet-2366	295	82	%	%	NOUN
admet-2366	295	83	at	at	ADP
admet-2366	295	84	the	the	DET
admet-2366	295	85	end	end	NOUN
admet-2366	295	86	of	of	ADP
admet-2366	295	87	1	1	NUM
admet-2366	295	88	,	,	PUNCT
admet-2366	295	89	2	2	NUM
admet-2366	295	90	,	,	PUNCT
admet-2366	295	91	3	3	NUM
admet-2366	295	92	,	,	PUNCT
admet-2366	295	93	and	and	CCONJ
admet-2366	295	94	6	6	NUM
admet-2366	295	95	months	month	NOUN
admet-2366	295	96	,	,	PUNCT
admet-2366	295	97	respectively	respectively	ADV
admet-2366	295	98	.	.	PUNCT
admet-2366	296	1	table	table	NOUN
admet-2366	296	2	4	4	NUM
admet-2366	296	3	.	.	PUNCT
admet-2366	296	4	results	result	NOUN
admet-2366	296	5	of	of	ADP
admet-2366	296	6	stability	stability	NOUN
admet-2366	296	7	studies	study	NOUN
admet-2366	296	8	of	of	ADP
admet-2366	296	9	unadorned	unadorned	ADJ
admet-2366	296	10	and	and	CCONJ
admet-2366	296	11	surface	surface	NOUN
admet-2366	296	12	-	-	PUNCT
admet-2366	296	13	adorned	adorn	VERB
admet-2366	296	14	nanoliposomal	nanoliposomal	ADJ
admet-2366	296	15	formulations	formulation	NOUN
admet-2366	296	16	.	.	PUNCT
admet-2366	297	1	time	time	NOUN
admet-2366	297	2	initial	initial	ADJ
admet-2366	297	3	1	1	NUM
admet-2366	297	4	month	month	NOUN
admet-2366	297	5	2	2	NUM
admet-2366	297	6	months	month	NOUN
admet-2366	297	7	3	3	NUM
admet-2366	297	8	months	month	NOUN
admet-2366	297	9	6	6	NUM
admet-2366	297	10	months	month	NOUN
admet-2366	297	11	parameters	parameter	NOUN
admet-2366	297	12	4	4	NUM
admet-2366	297	13	°	°	SYM
admet-2366	297	14	c	c	NOUN
admet-2366	297	15	25	25	NUM
admet-2366	297	16	°	°	NOUN
admet-2366	297	17	c	c	PROPN
admet-2366	297	18	45	45	NUM
admet-2366	297	19	°	°	NOUN
admet-2366	297	20	c	c	NOUN
admet-2366	297	21	4	4	NUM
admet-2366	297	22	°	°	NOUN
admet-2366	297	23	c	c	NOUN
admet-2366	297	24	25	25	NUM
admet-2366	297	25	°	°	NOUN
admet-2366	297	26	c	c	PROPN
admet-2366	297	27	45	45	NUM
admet-2366	297	28	°	°	NOUN
admet-2366	297	29	c	c	NOUN
admet-2366	297	30	4	4	NUM
admet-2366	297	31	°	°	NOUN
admet-2366	297	32	c	c	NOUN
admet-2366	297	33	25	25	NUM
admet-2366	297	34	°	°	NOUN
admet-2366	297	35	c	c	PROPN
admet-2366	297	36	45	45	NUM
admet-2366	297	37	°	°	NOUN
admet-2366	297	38	c	c	NOUN
admet-2366	297	39	4	4	NUM
admet-2366	297	40	°	°	NOUN
admet-2366	297	41	c	c	NOUN
admet-2366	297	42	25	25	NUM
admet-2366	297	43	°	°	NOUN
admet-2366	297	44	c	c	PROPN
admet-2366	297	45	45	45	NUM
admet-2366	297	46	°	°	NOUN
admet-2366	297	47	c	c	NOUN
admet-2366	297	48	4	4	NUM
admet-2366	297	49	°	°	NOUN
admet-2366	297	50	c	c	NOUN
admet-2366	297	51	25	25	NUM
admet-2366	297	52	°	°	NOUN
admet-2366	297	53	c	c	PROPN
admet-2366	297	54	45	45	NUM
admet-2366	297	55	°	°	NOUN
admet-2366	297	56	c	c	NOUN
admet-2366	297	57	unadorned	unadorned	ADJ
admet-2366	297	58	gefitinib	gefitinib	NOUN
admet-2366	297	59	nanoliposomes	nanoliposome	VERB
admet-2366	297	60	encapsulatio	encapsulatio	NOUN
admet-2366	297	61	n	n	PRON
admet-2366	297	62	efficiency	efficiency	NOUN
admet-2366	297	63	,	,	PUNCT
admet-2366	297	64	%	%	NOUN
admet-2366	297	65	87.56	87.56	NUM
admet-2366	297	66	±0.17	±0.17	PROPN
admet-2366	297	67	87.56±	87.56±	NUM
admet-2366	297	68	0.17	0.17	NUM
admet-2366	297	69	87.56±0	87.56±0	PROPN
admet-2366	297	70	.17	.17	NUM
admet-2366	297	71	78.75	78.75	NUM
admet-2366	297	72	±0.56	±0.56	PROPN
admet-2366	297	73	73.46±	73.46±	NUM
admet-2366	297	74	1.23	1.23	NUM
admet-2366	297	75	48.27±	48.27±	NUM
admet-2366	297	76	4.34	4.34	NUM
admet-2366	297	77	70.36	70.36	NUM
admet-2366	297	78	±2.98	±2.98	PROPN
admet-2366	297	79	55.46±	55.46±	NUM
admet-2366	297	80	2.45	2.45	NUM
admet-2366	297	81	30.02±	30.02±	NUM
admet-2366	297	82	2.15	2.15	NUM
admet-2366	297	83	61.75	61.75	NUM
admet-2366	297	84	±4.67	±4.67	PROPN
admet-2366	297	85	31.27±	31.27±	NUM
admet-2366	297	86	3.45	3.45	NUM
admet-2366	297	87	15.36±	15.36±	NUM
admet-2366	297	88	2.78	2.78	NUM
admet-2366	297	89	61.75	61.75	NUM
admet-2366	297	90	±4.67	±4.67	PROPN
admet-2366	297	91	29.27±	29.27±	NUM
admet-2366	297	92	3.45	3.45	NUM
admet-2366	297	93	5.36	5.36	NUM
admet-2366	297	94	±2.78	±2.78	NOUN
admet-2366	297	95	particle	particle	NOUN
admet-2366	297	96	size	size	NOUN
admet-2366	297	97	,	,	PUNCT
admet-2366	297	98	nm	nm	PROPN
admet-2366	297	99	93.20	93.20	NUM
admet-2366	297	100	±3.25	±3.25	NOUN
admet-2366	297	101	93.20±	93.20±	NUM
admet-2366	297	102	3.25	3.25	NUM
admet-2366	297	103	93.20±3	93.20±3	NUM
admet-2366	297	104	.25	.25	NUM
admet-2366	297	105	128.7	128.7	NUM
admet-2366	297	106	±3.06	±3.06	PROPN
admet-2366	297	107	279.5±	279.5±	NUM
admet-2366	297	108	3.09	3.09	NUM
admet-2366	297	109	528.3±	528.3±	NUM
admet-2366	297	110	5.45	5.45	NUM
admet-2366	297	111	148.2	148.2	NUM
admet-2366	297	112	±4.89	±4.89	NOUN
admet-2366	297	113	345.5±	345.5±	NUM
admet-2366	297	114	3.89	3.89	NUM
admet-2366	297	115	8898±	8898±	NUM
admet-2366	297	116	4.45	4.45	NUM
admet-2366	297	117	220.8	220.8	NUM
admet-2366	297	118	±4.89	±4.89	PROPN
admet-2366	297	119	1772±	1772±	NUM
admet-2366	297	120	10.23	10.23	NUM
admet-2366	297	121	420.8	420.8	NUM
admet-2366	297	122	±4.89	±4.89	PROPN
admet-2366	297	123	appearance	appearance	NOUN
admet-2366	297	124	clear	clear	ADJ
admet-2366	297	125	translucent	translucent	ADJ
admet-2366	297	126	milky	milky	ADJ
admet-2366	297	127	*	*	PUNCT
admet-2366	297	128	milky	milky	ADJ
admet-2366	297	129	*	*	PUNCT
admet-2366	298	1	*	*	PUNCT
admet-2366	298	2	*	*	PUNCT
admet-2366	298	3	milky	milky	ADJ
admet-2366	298	4	*	*	PUNCT
admet-2366	298	5	*	*	PUNCT
admet-2366	298	6	*	*	PUNCT
admet-2366	298	7	surface	surface	NOUN
admet-2366	298	8	adorned	adorn	VERB
admet-2366	298	9	gefitinib	gefitinib	NOUN
admet-2366	298	10	nanoliposomes	nanoliposome	VERB
admet-2366	298	11	encapsulatio	encapsulatio	NOUN
admet-2366	298	12	n	n	PRON
admet-2366	298	13	efficiency	efficiency	NOUN
admet-2366	298	14	,	,	PUNCT
admet-2366	298	15	%	%	NOUN
admet-2366	298	16	88.46	88.46	NUM
admet-2366	298	17	±0.97	±0.97	NOUN
admet-2366	298	18	88.46±	88.46±	NUM
admet-2366	298	19	0.97	0.97	NUM
admet-2366	298	20	88.46±	88.46±	NUM
admet-2366	298	21	0.97	0.97	NUM
admet-2366	298	22	83.69	83.69	NUM
admet-2366	298	23	±0.65	±0.65	PROPN
admet-2366	298	24	76.96±	76.96±	NUM
admet-2366	298	25	2.39	2.39	NUM
admet-2366	298	26	50.79±	50.79±	NUM
admet-2366	298	27	4.35	4.35	NUM
admet-2366	298	28	81.23	81.23	NUM
admet-2366	298	29	±1.64	±1.64	NOUN
admet-2366	298	30	61.76±	61.76±	NUM
admet-2366	298	31	2.09	2.09	NUM
admet-2366	298	32	32.46	32.46	NUM
admet-2366	298	33	1.98	1.98	NUM
admet-2366	298	34	70.56	70.56	NUM
admet-2366	298	35	±5.23	±5.23	PROPN
admet-2366	298	36	32.36±	32.36±	NUM
admet-2366	298	37	2.34	2.34	NUM
admet-2366	298	38	16.79±	16.79±	NUM
admet-2366	298	39	3.89	3.89	NUM
admet-2366	298	40	68.56	68.56	NUM
admet-2366	298	41	±5.23	±5.23	ADP
admet-2366	298	42	30.36	30.36	NUM
admet-2366	298	43	±2.34	±2.34	PROPN
admet-2366	298	44	6.79	6.79	NUM
admet-2366	298	45	±3.89	±3.89	PROPN
admet-2366	298	46	particle	particle	NOUN
admet-2366	298	47	size	size	NOUN
admet-2366	298	48	,	,	PUNCT
admet-2366	298	49	nm	nm	ADJ
admet-2366	298	50	132.7	132.7	NUM
admet-2366	298	51	±4.56	±4.56	NOUN
admet-2366	298	52	132.7±	132.7±	NUM
admet-2366	298	53	4.56	4.56	NUM
admet-2366	298	54	132.7±	132.7±	NUM
admet-2366	298	55	4.56	4.56	NUM
admet-2366	298	56	139.5	139.5	NUM
admet-2366	298	57	±4.65	±4.65	NOUN
admet-2366	298	58	212.2±	212.2±	NUM
admet-2366	298	59	4.89	4.89	NUM
admet-2366	298	60	440.8±	440.8±	NUM
admet-2366	298	61	7.23	7.23	NUM
admet-2366	298	62	153.5	153.5	NUM
admet-2366	298	63	±5.67	±5.67	PROPN
admet-2366	298	64	309.5±	309.5±	NUM
admet-2366	298	65	4.96	4.96	NUM
admet-2366	298	66	7366±	7366±	NUM
admet-2366	298	67	4.12	4.12	NUM
admet-2366	298	68	172.6	172.6	NUM
admet-2366	298	69	±5.02	±5.02	PROPN
admet-2366	298	70	1211±	1211±	NUM
admet-2366	298	71	12.23	12.23	NUM
admet-2366	298	72	372.6	372.6	NUM
admet-2366	298	73	±5.02	±5.02	PROPN
admet-2366	298	74	*	*	PUNCT
admet-2366	298	75	yellowish	yellowish	ADJ
admet-2366	298	76	suspension	suspension	NOUN
admet-2366	298	77	with	with	ADP
admet-2366	298	78	minute	minute	ADJ
admet-2366	298	79	bunches	bunche	NOUN
admet-2366	298	80	of	of	ADP
admet-2366	298	81	particles	particle	NOUN
admet-2366	298	82	discrete	discrete	ADJ
admet-2366	298	83	on	on	ADP
admet-2366	298	84	shaking	shake	VERB
admet-2366	298	85	.	.	PUNCT
admet-2366	299	1	*	*	PUNCT
admet-2366	299	2	*	*	PUNCT
admet-2366	299	3	murky	murky	ADJ
admet-2366	299	4	suspension	suspension	NOUN
admet-2366	299	5	with	with	ADP
admet-2366	299	6	fungus	fungus	NOUN
admet-2366	299	7	clusters	cluster	NOUN
admet-2366	299	8	does	do	AUX
admet-2366	299	9	not	not	PART
admet-2366	299	10	discrete	discrete	VERB
admet-2366	299	11	on	on	ADP
admet-2366	299	12	shaking	shake	VERB
admet-2366	299	13	.	.	PUNCT
admet-2366	300	1	the	the	DET
admet-2366	300	2	physical	physical	ADJ
admet-2366	300	3	appearance	appearance	NOUN
admet-2366	300	4	of	of	ADP
admet-2366	300	5	nanoliposomal	nanoliposomal	ADJ
admet-2366	300	6	preparations	preparation	NOUN
admet-2366	300	7	was	be	AUX
admet-2366	300	8	observed	observe	VERB
admet-2366	300	9	at	at	ADP
admet-2366	300	10	4	4	NUM
admet-2366	300	11	,	,	PUNCT
admet-2366	300	12	25	25	NUM
admet-2366	300	13	and	and	CCONJ
admet-2366	300	14	45	45	NUM
admet-2366	300	15	°	°	NOUN
admet-2366	300	16	c	c	NOUN
admet-2366	300	17	for	for	ADP
admet-2366	300	18	the	the	DET
admet-2366	300	19	first	first	ADJ
admet-2366	300	20	,	,	PUNCT
admet-2366	300	21	second	second	ADJ
admet-2366	300	22	,	,	PUNCT
admet-2366	300	23	third	third	ADJ
admet-2366	300	24	,	,	PUNCT
admet-2366	300	25	and	and	CCONJ
admet-2366	300	26	sixth	sixth	ADJ
admet-2366	300	27	months	month	NOUN
admet-2366	300	28	.	.	PUNCT
admet-2366	301	1	following	follow	VERB
admet-2366	301	2	the	the	DET
admet-2366	301	3	first	first	ADJ
admet-2366	301	4	month	month	NOUN
admet-2366	301	5	,	,	PUNCT
admet-2366	301	6	the	the	DET
admet-2366	301	7	sample	sample	NOUN
admet-2366	301	8	at	at	ADP
admet-2366	301	9	45	45	NUM
admet-2366	301	10	°	°	NOUN
admet-2366	301	11	c	c	NOUN
admet-2366	301	12	showed	show	VERB
admet-2366	301	13	an	an	DET
admet-2366	301	14	alteration	alteration	NOUN
admet-2366	301	15	in	in	ADP
admet-2366	301	16	the	the	DET
admet-2366	301	17	colour	colour	NOUN
admet-2366	301	18	and	and	CCONJ
admet-2366	301	19	viscosity	viscosity	NOUN
admet-2366	301	20	of	of	ADP
admet-2366	301	21	the	the	DET
admet-2366	301	22	preparations	preparation	NOUN
admet-2366	301	23	with	with	ADP
admet-2366	301	24	a	a	DET
admet-2366	301	25	small	small	ADJ
admet-2366	301	26	accretion	accretion	NOUN
admet-2366	301	27	of	of	ADP
admet-2366	301	28	particles	particle	NOUN
admet-2366	301	29	,	,	PUNCT
admet-2366	301	30	but	but	CCONJ
admet-2366	301	31	they	they	PRON
admet-2366	301	32	were	be	AUX
admet-2366	301	33	dispersed	disperse	VERB
admet-2366	301	34	on	on	ADP
admet-2366	301	35	quaking	quake	VERB
admet-2366	301	36	.	.	PUNCT
admet-2366	302	1	however	however	ADV
admet-2366	302	2	,	,	PUNCT
admet-2366	302	3	the	the	DET
admet-2366	302	4	samples	sample	NOUN
admet-2366	302	5	kept	keep	VERB
admet-2366	302	6	at	at	ADP
admet-2366	302	7	4	4	NUM
admet-2366	302	8	and	and	CCONJ
admet-2366	302	9	25	25	NUM
admet-2366	303	1	°	°	NOUN
admet-2366	303	2	c	c	NOUN
admet-2366	303	3	were	be	AUX
admet-2366	303	4	found	find	VERB
admet-2366	303	5	to	to	PART
admet-2366	303	6	be	be	AUX
admet-2366	303	7	acceptable	acceptable	ADJ
admet-2366	303	8	.	.	PUNCT
admet-2366	304	1	traces	trace	NOUN
admet-2366	304	2	of	of	ADP
admet-2366	304	3	fungal	fungal	ADJ
admet-2366	304	4	growth	growth	NOUN
admet-2366	304	5	were	be	AUX
admet-2366	304	6	observed	observe	VERB
admet-2366	304	7	above	above	ADP
admet-2366	304	8	the	the	DET
admet-2366	304	9	formulation	formulation	NOUN
admet-2366	304	10	horde	horde	NOUN
admet-2366	304	11	at	at	ADP
admet-2366	304	12	45	45	NUM
admet-2366	304	13	°	°	NOUN
admet-2366	304	14	c	c	NOUN
admet-2366	304	15	in	in	ADP
admet-2366	304	16	the	the	DET
admet-2366	304	17	latter	latter	ADJ
admet-2366	304	18	part	part	NOUN
admet-2366	304	19	of	of	ADP
admet-2366	304	20	the	the	DET
admet-2366	304	21	second	second	ADJ
admet-2366	304	22	month	month	NOUN
admet-2366	304	23	,	,	PUNCT
admet-2366	304	24	prompting	prompt	VERB
admet-2366	304	25	the	the	DET
admet-2366	304	26	decision	decision	NOUN
admet-2366	304	27	to	to	PART
admet-2366	304	28	end	end	VERB
admet-2366	304	29	the	the	DET
admet-2366	304	30	batch	batch	NOUN
admet-2366	304	31	's	's	PART
admet-2366	304	32	studies	study	NOUN
admet-2366	304	33	after	after	ADP
admet-2366	304	34	two	two	NUM
admet-2366	304	35	months	month	NOUN
admet-2366	304	36	.	.	PUNCT
admet-2366	305	1	nanoliposomes	nanoliposome	NOUN
admet-2366	305	2	stored	store	VERB
admet-2366	305	3	at	at	ADP
admet-2366	305	4	4	4	NUM
admet-2366	305	5	and	and	CCONJ
admet-2366	305	6	25	25	NUM
admet-2366	305	7	°	°	NOUN
admet-2366	305	8	c	c	NOUN
admet-2366	305	9	showed	show	VERB
admet-2366	305	10	no	no	DET
admet-2366	305	11	discernible	discernible	ADJ
admet-2366	305	12	changes	change	NOUN
admet-2366	305	13	in	in	ADP
admet-2366	305	14	particle	particle	NOUN
admet-2366	305	15	dimension	dimension	NOUN
admet-2366	305	16	when	when	SCONJ
admet-2366	305	17	compared	compare	VERB
admet-2366	305	18	to	to	ADP
admet-2366	305	19	nanoliposomes	nanoliposomes	ADV
admet-2366	305	20	stored	store	VERB
admet-2366	305	21	at	at	ADP
admet-2366	305	22	45	45	NUM
admet-2366	305	23	°	°	NOUN
admet-2366	305	24	c	c	NOUN
admet-2366	305	25	.	.	PUNCT
admet-2366	306	1	the	the	DET
admet-2366	306	2	sample	sample	NOUN
admet-2366	306	3	stored	store	VERB
admet-2366	306	4	at	at	ADP
admet-2366	306	5	25	25	NUM
admet-2366	306	6	°	°	NOUN
admet-2366	306	7	c	c	NOUN
admet-2366	306	8	had	have	VERB
admet-2366	306	9	traces	trace	NOUN
admet-2366	306	10	of	of	ADP
admet-2366	306	11	fungal	fungal	ADJ
admet-2366	306	12	growth	growth	NOUN
admet-2366	306	13	as	as	ADP
admet-2366	306	14	of	of	ADP
admet-2366	306	15	the	the	DET
admet-2366	306	16	end	end	NOUN
admet-2366	306	17	of	of	ADP
admet-2366	306	18	the	the	DET
admet-2366	306	19	third	third	ADJ
admet-2366	306	20	month	month	NOUN
admet-2366	306	21	,	,	PUNCT
admet-2366	306	22	while	while	SCONJ
admet-2366	306	23	batches	batch	NOUN
admet-2366	306	24	at	at	ADP
admet-2366	306	25	4	4	NUM
admet-2366	306	26	°	°	NOUN
admet-2366	306	27	c	c	NOUN
admet-2366	306	28	were	be	AUX
admet-2366	306	29	found	find	VERB
admet-2366	306	30	to	to	PART
admet-2366	306	31	be	be	AUX
admet-2366	306	32	stable	stable	ADJ
admet-2366	306	33	.	.	PUNCT
admet-2366	307	1	at	at	ADP
admet-2366	307	2	the	the	DET
admet-2366	307	3	closing	closing	NOUN
admet-2366	307	4	stages	stage	NOUN
admet-2366	307	5	of	of	ADP
admet-2366	307	6	the	the	DET
admet-2366	307	7	sixth	sixth	ADJ
admet-2366	307	8	month	month	NOUN
admet-2366	307	9	,	,	PUNCT
admet-2366	307	10	the	the	DET
admet-2366	307	11	samples	sample	NOUN
admet-2366	307	12	stored	store	VERB
admet-2366	307	13	at	at	ADP
admet-2366	307	14	4	4	NUM
admet-2366	307	15	°	°	NOUN
admet-2366	307	16	c	c	NOUN
admet-2366	307	17	were	be	AUX
admet-2366	307	18	found	find	VERB
admet-2366	307	19	to	to	PART
admet-2366	307	20	be	be	AUX
admet-2366	307	21	more	more	ADV
admet-2366	307	22	stable	stable	ADJ
admet-2366	307	23	than	than	ADP
admet-2366	307	24	the	the	DET
admet-2366	307	25	samples	sample	NOUN
admet-2366	307	26	stored	store	VERB
admet-2366	307	27	at	at	ADP
admet-2366	307	28	25	25	NUM
admet-2366	307	29	and	and	CCONJ
admet-2366	307	30	45	45	NUM
admet-2366	308	1	°	°	NOUN
admet-2366	308	2	c	c	NOUN
admet-2366	308	3	.	.	PUNCT
admet-2366	309	1	table	table	NOUN
admet-2366	309	2	4	4	NUM
admet-2366	309	3	shows	show	VERB
admet-2366	309	4	the	the	DET
admet-2366	309	5	results	result	NOUN
admet-2366	309	6	of	of	ADP
admet-2366	309	7	the	the	DET
admet-2366	309	8	percentage	percentage	NOUN
admet-2366	309	9	encapsulation	encapsulation	NOUN
admet-2366	309	10	efficiency	efficiency	NOUN
admet-2366	309	11	,	,	PUNCT
admet-2366	309	12	particle	particle	NOUN
admet-2366	309	13	size	size	NOUN
admet-2366	309	14	,	,	PUNCT
admet-2366	309	15	and	and	CCONJ
admet-2366	309	16	physical	physical	ADJ
admet-2366	309	17	appearance	appearance	NOUN
admet-2366	309	18	of	of	ADP
admet-2366	309	19	the	the	DET
admet-2366	309	20	preparations	preparation	NOUN
admet-2366	309	21	after	after	ADP
admet-2366	309	22	6	6	NUM
admet-2366	309	23	months	month	NOUN
admet-2366	309	24	.	.	PUNCT
admet-2366	310	1	discussion	discussion	NOUN
admet-2366	310	2	in	in	ADP
admet-2366	310	3	comparison	comparison	NOUN
admet-2366	310	4	to	to	ADP
admet-2366	310	5	other	other	ADJ
admet-2366	310	6	targeted	target	VERB
admet-2366	310	7	drug	drug	NOUN
admet-2366	310	8	delivery	delivery	NOUN
admet-2366	310	9	systems	system	NOUN
admet-2366	310	10	,	,	PUNCT
admet-2366	310	11	nanoliposomes	nanoliposome	NOUN
admet-2366	310	12	have	have	AUX
admet-2366	310	13	received	receive	VERB
admet-2366	310	14	the	the	DET
admet-2366	310	15	most	most	ADJ
admet-2366	310	16	attention	attention	NOUN
admet-2366	310	17	because	because	SCONJ
admet-2366	310	18	of	of	ADP
admet-2366	310	19	their	their	PRON
admet-2366	310	20	ability	ability	NOUN
admet-2366	310	21	to	to	PART
admet-2366	310	22	encapsulate	encapsulate	VERB
admet-2366	310	23	a	a	DET
admet-2366	310	24	variety	variety	NOUN
admet-2366	310	25	of	of	ADP
admet-2366	310	26	drugs	drug	NOUN
admet-2366	310	27	,	,	PUNCT
admet-2366	310	28	their	their	PRON
admet-2366	310	29	low	low	ADJ
admet-2366	310	30	toxicity	toxicity	NOUN
admet-2366	310	31	,	,	PUNCT
admet-2366	310	32	good	good	ADJ
admet-2366	310	33	biocompatibility	biocompatibility	NOUN
admet-2366	310	34	,	,	PUNCT
admet-2366	310	35	and	and	CCONJ
admet-2366	310	36	lack	lack	NOUN
admet-2366	310	37	of	of	ADP
admet-2366	310	38	immune	immune	ADJ
admet-2366	310	39	system	system	NOUN
admet-2366	310	40	activation	activation	NOUN
admet-2366	310	41	or	or	CCONJ
admet-2366	310	42	suppression	suppression	NOUN
admet-2366	310	43	[	[	X
admet-2366	310	44	50	50	NUM
admet-2366	310	45	]	]	PUNCT
admet-2366	310	46	.	.	PUNCT
admet-2366	311	1	nanoliposomes	nanoliposome	NOUN
admet-2366	311	2	may	may	AUX
admet-2366	311	3	control	control	VERB
admet-2366	311	4	the	the	DET
admet-2366	311	5	rate	rate	NOUN
admet-2366	311	6	at	at	ADP
admet-2366	311	7	which	which	PRON
admet-2366	311	8	the	the	DET
admet-2366	311	9	component	component	NOUN
admet-2366	311	10	they	they	PRON
admet-2366	311	11	encase	encase	VERB
admet-2366	311	12	is	be	AUX
admet-2366	311	13	released	release	VERB
admet-2366	311	14	while	while	SCONJ
admet-2366	311	15	shielding	shield	VERB
admet-2366	311	16	the	the	DET
admet-2366	311	17	compound	compound	NOUN
admet-2366	311	18	from	from	ADP
admet-2366	311	19	any	any	DET
admet-2366	311	20	chemical	chemical	ADJ
admet-2366	311	21	disturbances	disturbance	NOUN
admet-2366	311	22	in	in	ADP
admet-2366	311	23	the	the	DET
admet-2366	311	24	nearby	nearby	ADJ
admet-2366	311	25	dispersal	dispersal	NOUN
admet-2366	311	26	medium	medium	NOUN
admet-2366	311	27	.	.	PUNCT
admet-2366	311	28	hydrophobic	hydrophobic	NOUN
admet-2366	311	29	tail	tail	NOUN
admet-2366	311	30	and	and	CCONJ
admet-2366	311	31	hydrophilic	hydrophilic	ADJ
admet-2366	311	32	head	head	NOUN
admet-2366	311	33	domains	domain	NOUN
admet-2366	311	34	are	be	AUX
admet-2366	311	35	present	present	ADJ
admet-2366	311	36	in	in	ADP
admet-2366	311	37	amphiphilic	amphiphilic	ADJ
admet-2366	311	38	phospholipids	phospholipid	NOUN
admet-2366	311	39	.	.	PUNCT
admet-2366	312	1	in	in	ADP
admet-2366	312	2	aqueous	aqueous	ADJ
admet-2366	312	3	media	medium	NOUN
admet-2366	312	4	,	,	PUNCT
admet-2366	312	5	it	it	PRON
admet-2366	312	6	created	create	VERB
admet-2366	312	7	nanoliposomes	nanoliposome	NOUN
admet-2366	312	8	with	with	ADP
admet-2366	312	9	a	a	DET
admet-2366	312	10	hydrophobic	hydrophobic	NOUN
admet-2366	312	11	inside	inside	ADV
admet-2366	312	12	and	and	CCONJ
admet-2366	312	13	a	a	DET
admet-2366	312	14	water	water	NOUN
admet-2366	312	15	-	-	PUNCT
admet-2366	312	16	soluble	soluble	ADJ
admet-2366	312	17	outside	outside	NOUN
admet-2366	312	18	.	.	PUNCT
admet-2366	313	1	to	to	PART
admet-2366	313	2	optimise	optimise	VERB
admet-2366	313	3	parameters	parameter	NOUN
admet-2366	313	4	including	include	VERB
admet-2366	313	5	x1	x1	PROPN
admet-2366	313	6	,	,	PUNCT
admet-2366	313	7	x2	x2	PROPN
admet-2366	313	8	,	,	PUNCT
admet-2366	313	9	and	and	CCONJ
admet-2366	313	10	x3	x3	ADJ
admet-2366	313	11	,	,	PUNCT
admet-2366	313	12	a	a	DET
admet-2366	313	13	total	total	NOUN
admet-2366	313	14	of	of	ADP
admet-2366	313	15	17	17	NUM
admet-2366	313	16	gefitinib	gefitinib	NOUN
admet-2366	313	17	-	-	PUNCT
admet-2366	313	18	loaded	load	VERB
admet-2366	313	19	nanoliposomal	nanoliposomal	ADJ
admet-2366	313	20	formulations	formulation	NOUN
admet-2366	313	21	were	be	AUX
admet-2366	313	22	formulated	formulate	VERB
admet-2366	313	23	in	in	ADP
admet-2366	313	24	the	the	DET
admet-2366	313	25	current	current	ADJ
admet-2366	313	26	investigation	investigation	NOUN
admet-2366	313	27	.	.	PUNCT
admet-2366	314	1	the	the	DET
admet-2366	314	2	centre	centre	NOUN
admet-2366	314	3	points	point	NOUN
admet-2366	314	4	,	,	PUNCT
admet-2366	314	5	which	which	PRON
admet-2366	314	6	represent	represent	VERB
admet-2366	314	7	the	the	DET
admet-2366	314	8	core	core	ADJ
admet-2366	314	9	values	value	NOUN
admet-2366	314	10	of	of	ADP
admet-2366	314	11	all	all	DET
admet-2366	314	12	components	component	NOUN
admet-2366	314	13	,	,	PUNCT
admet-2366	314	14	are	be	AUX
admet-2366	314	15	also	also	ADV
admet-2366	314	16	presented	present	VERB
admet-2366	314	17	.	.	PUNCT
admet-2366	315	1	multiple	multiple	ADJ
admet-2366	315	2	linear	linear	PROPN
admet-2366	315	3	regression	regression	NOUN
admet-2366	315	4	analysis	analysis	NOUN
admet-2366	315	5	was	be	AUX
admet-2366	315	6	carried	carry	VERB
admet-2366	315	7	out	out	ADP
admet-2366	315	8	using	use	VERB
admet-2366	315	9	design	design	NOUN
admet-2366	315	10	expert	expert	NOUN
admet-2366	315	11	software	software	NOUN
admet-2366	315	12	(	(	PUNCT
admet-2366	315	13	version	version	NOUN
admet-2366	315	14	11.0	11.0	NUM
admet-2366	315	15	,	,	PUNCT
admet-2366	315	16	stat	stat	NOUN
admet-2366	315	17	-	-	PUNCT
admet-2366	315	18	ease	ease	NOUN
admet-2366	315	19	,	,	PUNCT
admet-2366	315	20	inc	inc	PROPN
admet-2366	315	21	.	.	PROPN
admet-2366	315	22	,	,	PUNCT
admet-2366	315	23	minneapolis	minneapolis	PROPN
admet-2366	315	24	,	,	PUNCT
admet-2366	315	25	mn	mn	PROPN
admet-2366	315	26	)	)	PUNCT
admet-2366	315	27	to	to	PART
admet-2366	315	28	determine	determine	VERB
admet-2366	315	29	the	the	DET
admet-2366	315	30	contribution	contribution	NOUN
admet-2366	315	31	of	of	ADP
admet-2366	315	32	different	different	ADJ
admet-2366	315	33	parameters	parameter	NOUN
admet-2366	315	34	for	for	ADP
admet-2366	315	35	particle	particle	NOUN
admet-2366	315	36	size	size	NOUN
admet-2366	315	37	and	and	CCONJ
admet-2366	315	38	encapsulation	encapsulation	NOUN
admet-2366	315	39	effectiveness	effectiveness	NOUN
admet-2366	315	40	.	.	PUNCT
admet-2366	316	1	the	the	DET
admet-2366	316	2	model	model	NOUN
admet-2366	316	3	was	be	AUX
admet-2366	316	4	considered	consider	VERB
admet-2366	316	5	significant	significant	ADJ
admet-2366	316	6	at	at	ADP
admet-2366	316	7	p	p	X
admet-2366	316	8	<	<	X
admet-2366	316	9	0.05	0.05	NUM
admet-2366	316	10	.	.	PUNCT
admet-2366	317	1	utilizing	utilize	VERB
admet-2366	317	2	design	design	NOUN
admet-2366	317	3	expect	expect	VERB
admet-2366	317	4	software	software	NOUN
admet-2366	317	5	version	version	NOUN
admet-2366	317	6	11	11	NUM
admet-2366	317	7	,	,	PUNCT
admet-2366	317	8	multiple	multiple	ADJ
admet-2366	317	9	linear	linear	ADJ
admet-2366	317	10	regression	regression	NOUN
admet-2366	317	11	analysis	analysis	NOUN
admet-2366	317	12	was	be	AUX
admet-2366	317	13	carried	carry	VERB
admet-2366	317	14	out	out	ADP
admet-2366	317	15	to	to	PART
admet-2366	317	16	ascertain	ascertain	VERB
admet-2366	317	17	how	how	SCONJ
admet-2366	317	18	different	different	ADJ
admet-2366	317	19	factors	factor	NOUN
admet-2366	317	20	affected	affect	VERB
admet-2366	317	21	particle	particle	NOUN
admet-2366	317	22	size	size	NOUN
admet-2366	317	23	and	and	CCONJ
admet-2366	317	24	entrapment	entrapment	NOUN
admet-2366	317	25	effectiveness	effectiveness	NOUN
admet-2366	317	26	.	.	PUNCT
admet-2366	318	1	the	the	DET
admet-2366	318	2	data	datum	NOUN
admet-2366	318	3	showed	show	VERB
admet-2366	318	4	that	that	SCONJ
admet-2366	318	5	admet	admet	PROPN
admet-2366	318	6	&	&	CCONJ
admet-2366	318	7	dmpk	dmpk	PROPN
admet-2366	318	8	12(4	12(4	PROPN
admet-2366	318	9	)	)	PUNCT
admet-2366	318	10	(	(	PUNCT
admet-2366	318	11	2024	2024	NUM
admet-2366	318	12	)	)	PUNCT
admet-2366	318	13	657	657	NUM
admet-2366	318	14	-	-	SYM
admet-2366	318	15	677	677	NUM
admet-2366	318	16	optimizing	optimizing	NOUN
admet-2366	318	17	gefitinib	gefitinib	NOUN
admet-2366	318	18	nanoliposomes	nanoliposomes	ADV
admet-2366	318	19	doi	doi	ADV
admet-2366	318	20	:	:	PUNCT
admet-2366	318	21	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	DET
admet-2366	318	22	671	671	NUM
admet-2366	318	23	encapsulation	encapsulation	NOUN
admet-2366	318	24	efficiency	efficiency	NOUN
admet-2366	318	25	was	be	AUX
admet-2366	318	26	enhanced	enhance	VERB
admet-2366	318	27	at	at	ADP
admet-2366	318	28	lower	low	ADJ
admet-2366	318	29	x2	x2	PROPN
admet-2366	318	30	,	,	PUNCT
admet-2366	318	31	higher	high	ADJ
admet-2366	318	32	x3	x3	ADJ
admet-2366	318	33	and	and	CCONJ
admet-2366	318	34	x1	x1	PROPN
admet-2366	318	35	.	.	PUNCT
admet-2366	319	1	the	the	DET
admet-2366	319	2	results	result	NOUN
admet-2366	319	3	from	from	ADP
admet-2366	319	4	counterplots	counterplot	NOUN
admet-2366	319	5	for	for	ADP
admet-2366	319	6	entrapment	entrapment	ADJ
admet-2366	319	7	efficiency	efficiency	NOUN
admet-2366	319	8	agreed	agree	VERB
admet-2366	319	9	with	with	ADP
admet-2366	319	10	the	the	DET
admet-2366	319	11	pareto	pareto	ADJ
admet-2366	319	12	chart	chart	NOUN
admet-2366	319	13	's	's	PART
admet-2366	319	14	conclusions	conclusion	NOUN
admet-2366	319	15	.	.	PUNCT
admet-2366	320	1	the	the	DET
admet-2366	320	2	positive	positive	ADJ
admet-2366	320	3	value	value	NOUN
admet-2366	320	4	of	of	ADP
admet-2366	320	5	the	the	DET
admet-2366	320	6	estimated	estimate	VERB
admet-2366	320	7	coefficients	coefficient	NOUN
admet-2366	320	8	x1	x1	PROPN
admet-2366	320	9	and	and	CCONJ
admet-2366	320	10	x3	x3	PROPN
admet-2366	320	11	demonstrated	demonstrate	VERB
admet-2366	320	12	the	the	DET
admet-2366	320	13	improvement	improvement	NOUN
admet-2366	320	14	of	of	ADP
admet-2366	320	15	encapsulation	encapsulation	NOUN
admet-2366	320	16	efficiency	efficiency	NOUN
admet-2366	320	17	with	with	ADP
admet-2366	320	18	the	the	DET
admet-2366	320	19	addition	addition	NOUN
admet-2366	320	20	of	of	ADP
admet-2366	320	21	corresponding	correspond	VERB
admet-2366	320	22	particulars	particular	NOUN
admet-2366	320	23	.	.	PUNCT
admet-2366	321	1	the	the	DET
admet-2366	321	2	negative	negative	ADJ
admet-2366	321	3	values	value	NOUN
admet-2366	321	4	of	of	ADP
admet-2366	321	5	x2	x2	PROPN
admet-2366	321	6	demonstrated	demonstrate	VERB
admet-2366	321	7	the	the	DET
admet-2366	321	8	augmented	augment	VERB
admet-2366	321	9	entrapment	entrapment	ADJ
admet-2366	321	10	efficiency	efficiency	NOUN
admet-2366	321	11	with	with	ADP
admet-2366	321	12	the	the	DET
admet-2366	321	13	decline	decline	NOUN
admet-2366	321	14	in	in	ADP
admet-2366	321	15	the	the	DET
admet-2366	321	16	consequent	consequent	ADJ
admet-2366	321	17	variable	variable	NOUN
admet-2366	321	18	.	.	PUNCT
admet-2366	322	1	all	all	DET
admet-2366	322	2	preparations	preparation	NOUN
admet-2366	322	3	were	be	AUX
admet-2366	322	4	analysed	analyse	VERB
admet-2366	322	5	to	to	PART
admet-2366	322	6	estimate	estimate	VERB
admet-2366	322	7	their	their	PRON
admet-2366	322	8	particle	particle	NOUN
admet-2366	322	9	dimensions	dimension	NOUN
admet-2366	322	10	and	and	CCONJ
admet-2366	322	11	their	their	PRON
admet-2366	322	12	particle	particle	NOUN
admet-2366	322	13	distribution	distribution	NOUN
admet-2366	322	14	.	.	PUNCT
admet-2366	323	1	in	in	ADP
admet-2366	323	2	a	a	DET
admet-2366	323	3	congealed	congealed	ADJ
admet-2366	323	4	system	system	NOUN
admet-2366	323	5	,	,	PUNCT
admet-2366	323	6	the	the	DET
admet-2366	323	7	pdi	pdi	NOUN
admet-2366	323	8	is	be	AUX
admet-2366	323	9	generally	generally	ADV
admet-2366	323	10	expressed	express	VERB
admet-2366	323	11	as	as	ADP
admet-2366	323	12	a	a	DET
admet-2366	323	13	pointer	pointer	NOUN
admet-2366	323	14	for	for	ADP
admet-2366	323	15	particle	particle	NOUN
admet-2366	323	16	size	size	NOUN
admet-2366	323	17	distribution	distribution	NOUN
admet-2366	323	18	.	.	PUNCT
admet-2366	324	1	the	the	DET
admet-2366	324	2	value	value	NOUN
admet-2366	324	3	of	of	ADP
admet-2366	324	4	pdi	pdi	PROPN
admet-2366	324	5	recommends	recommend	VERB
admet-2366	324	6	a	a	DET
admet-2366	324	7	narrow	narrow	ADJ
admet-2366	324	8	or	or	CCONJ
admet-2366	324	9	wide	wide	ADJ
admet-2366	324	10	particle	particle	NOUN
admet-2366	324	11	size	size	NOUN
admet-2366	324	12	distribution	distribution	NOUN
admet-2366	324	13	pattern	pattern	NOUN
admet-2366	324	14	.	.	PUNCT
admet-2366	325	1	in	in	ADP
admet-2366	325	2	the	the	DET
admet-2366	325	3	current	current	ADJ
admet-2366	325	4	study	study	NOUN
admet-2366	325	5	,	,	PUNCT
admet-2366	325	6	the	the	DET
admet-2366	325	7	lower	low	ADJ
admet-2366	325	8	value	value	NOUN
admet-2366	325	9	of	of	ADP
admet-2366	325	10	pdi	pdi	NOUN
admet-2366	325	11	demonstrated	demonstrate	VERB
admet-2366	325	12	better	well	ADJ
admet-2366	325	13	consistency	consistency	NOUN
admet-2366	325	14	and	and	CCONJ
admet-2366	325	15	a	a	DET
admet-2366	325	16	narrower	narrow	ADJ
admet-2366	325	17	particle	particle	NOUN
admet-2366	325	18	size	size	NOUN
admet-2366	325	19	distribution	distribution	NOUN
admet-2366	325	20	.	.	PUNCT
admet-2366	326	1	the	the	DET
admet-2366	326	2	zeta	zeta	PROPN
admet-2366	326	3	potential	potential	ADJ
admet-2366	326	4	values	value	NOUN
admet-2366	326	5	indicated	indicate	VERB
admet-2366	326	6	the	the	DET
admet-2366	326	7	extent	extent	NOUN
admet-2366	326	8	of	of	ADP
admet-2366	326	9	repellence	repellence	NOUN
admet-2366	326	10	between	between	ADP
admet-2366	326	11	similarly	similarly	ADV
admet-2366	326	12	charged	charge	VERB
admet-2366	326	13	particles	particle	NOUN
admet-2366	326	14	and	and	CCONJ
admet-2366	326	15	the	the	DET
admet-2366	326	16	stability	stability	NOUN
admet-2366	326	17	of	of	ADP
admet-2366	326	18	vesicular	vesicular	ADJ
admet-2366	326	19	nanoformulations	nanoformulation	NOUN
admet-2366	326	20	.	.	PUNCT
admet-2366	327	1	as	as	SCONJ
admet-2366	327	2	the	the	DET
admet-2366	327	3	value	value	NOUN
admet-2366	327	4	of	of	ADP
admet-2366	327	5	zeta	zeta	PROPN
admet-2366	327	6	potential	potential	NOUN
admet-2366	327	7	increased	increase	VERB
admet-2366	327	8	,	,	PUNCT
admet-2366	327	9	the	the	DET
admet-2366	327	10	charged	charge	VERB
admet-2366	327	11	particles	particle	NOUN
admet-2366	327	12	in	in	ADP
admet-2366	327	13	a	a	DET
admet-2366	327	14	dispersal	dispersal	NOUN
admet-2366	327	15	system	system	NOUN
admet-2366	327	16	fended	fend	VERB
admet-2366	327	17	off	off	ADP
admet-2366	327	18	each	each	DET
admet-2366	327	19	other	other	ADJ
admet-2366	327	20	and	and	CCONJ
admet-2366	327	21	provided	provide	VERB
admet-2366	327	22	stability	stability	NOUN
admet-2366	327	23	against	against	ADP
admet-2366	327	24	accumulation	accumulation	NOUN
admet-2366	327	25	.	.	PUNCT
admet-2366	328	1	uncharged	uncharged	ADJ
admet-2366	328	2	vesicles	vesicle	NOUN
admet-2366	328	3	can	can	AUX
admet-2366	328	4	be	be	AUX
admet-2366	328	5	amassed	amass	VERB
admet-2366	328	6	easily	easily	ADV
admet-2366	328	7	.	.	PUNCT
admet-2366	329	1	in	in	ADP
admet-2366	329	2	the	the	DET
admet-2366	329	3	case	case	NOUN
admet-2366	329	4	of	of	ADP
admet-2366	329	5	nanodispersions	nanodispersion	NOUN
admet-2366	329	6	,	,	PUNCT
admet-2366	329	7	a	a	DET
admet-2366	329	8	zeta	zeta	NOUN
admet-2366	329	9	potential	potential	NOUN
admet-2366	329	10	of	of	ADP
admet-2366	329	11	±30	±30	PROPN
admet-2366	329	12	is	be	AUX
admet-2366	329	13	considered	consider	VERB
admet-2366	329	14	optimal	optimal	ADJ
admet-2366	329	15	for	for	ADP
admet-2366	329	16	stable	stable	ADJ
admet-2366	329	17	formulation	formulation	NOUN
admet-2366	329	18	.	.	PUNCT
admet-2366	330	1	beyond	beyond	ADP
admet-2366	330	2	and	and	CCONJ
admet-2366	330	3	beneath	beneath	ADP
admet-2366	330	4	this	this	PRON
admet-2366	330	5	,	,	PUNCT
admet-2366	330	6	a	a	DET
admet-2366	330	7	caking	caking	NOUN
admet-2366	330	8	zone	zone	NOUN
admet-2366	330	9	begins	begin	VERB
admet-2366	330	10	that	that	PRON
admet-2366	330	11	leads	lead	VERB
admet-2366	330	12	to	to	ADP
admet-2366	330	13	the	the	DET
admet-2366	330	14	accumulation	accumulation	NOUN
admet-2366	330	15	of	of	ADP
admet-2366	330	16	particles	particle	NOUN
admet-2366	330	17	[	[	X
admet-2366	330	18	51	51	NUM
admet-2366	330	19	]	]	PUNCT
admet-2366	330	20	.	.	PUNCT
admet-2366	331	1	the	the	DET
admet-2366	331	2	carboxyl	carboxyl	NOUN
admet-2366	331	3	groups	group	NOUN
admet-2366	331	4	on	on	ADP
admet-2366	331	5	fatty	fatty	NOUN
admet-2366	331	6	acid	acid	NOUN
admet-2366	331	7	moieties	moiety	NOUN
admet-2366	331	8	and	and	CCONJ
admet-2366	331	9	soya	soya	NOUN
admet-2366	331	10	lecithins	lecithin	NOUN
admet-2366	331	11	were	be	AUX
admet-2366	331	12	ionized	ionize	VERB
admet-2366	331	13	,	,	PUNCT
admet-2366	331	14	leading	lead	VERB
admet-2366	331	15	to	to	ADP
admet-2366	331	16	a	a	DET
admet-2366	331	17	negative	negative	ADJ
admet-2366	331	18	charge	charge	NOUN
admet-2366	331	19	on	on	ADP
admet-2366	331	20	particles	particle	NOUN
admet-2366	331	21	.	.	PUNCT
admet-2366	332	1	because	because	SCONJ
admet-2366	332	2	of	of	ADP
admet-2366	332	3	the	the	DET
admet-2366	332	4	ion	ion	NOUN
admet-2366	332	5	-	-	PUNCT
admet-2366	332	6	ion	ion	NOUN
admet-2366	332	7	interaction	interaction	NOUN
admet-2366	332	8	between	between	ADP
admet-2366	332	9	the	the	DET
admet-2366	332	10	negatively	negatively	ADV
admet-2366	332	11	charged	charge	VERB
admet-2366	332	12	surface	surface	NOUN
admet-2366	332	13	of	of	ADP
admet-2366	332	14	nanoliposomes	nanoliposome	NOUN
admet-2366	332	15	and	and	CCONJ
admet-2366	332	16	the	the	DET
admet-2366	332	17	free	free	ADJ
admet-2366	332	18	amino	amino	NOUN
admet-2366	332	19	groups	group	NOUN
admet-2366	332	20	of	of	ADP
admet-2366	332	21	chitosan	chitosan	NOUN
admet-2366	332	22	,	,	PUNCT
admet-2366	332	23	the	the	DET
admet-2366	332	24	negative	negative	ADJ
admet-2366	332	25	charge	charge	NOUN
admet-2366	332	26	was	be	AUX
admet-2366	332	27	transformed	transform	VERB
admet-2366	332	28	into	into	ADP
admet-2366	332	29	a	a	DET
admet-2366	332	30	positive	positive	ADJ
admet-2366	332	31	charge	charge	NOUN
admet-2366	332	32	[	[	X
admet-2366	332	33	52	52	NUM
admet-2366	332	34	]	]	PUNCT
admet-2366	332	35	.	.	PUNCT
admet-2366	333	1	the	the	DET
admet-2366	333	2	free	free	ADJ
admet-2366	333	3	amino	amino	NOUN
admet-2366	333	4	group	group	NOUN
admet-2366	333	5	of	of	ADP
admet-2366	333	6	chitosan	chitosan	NOUN
admet-2366	333	7	is	be	AUX
admet-2366	333	8	responsible	responsible	ADJ
admet-2366	333	9	for	for	ADP
admet-2366	333	10	its	its	PRON
admet-2366	333	11	positive	positive	ADJ
admet-2366	333	12	charge	charge	NOUN
admet-2366	333	13	in	in	ADP
admet-2366	333	14	acidic	acidic	ADJ
admet-2366	333	15	media	medium	NOUN
admet-2366	333	16	.	.	PUNCT
admet-2366	334	1	the	the	DET
admet-2366	334	2	low	low	ADJ
admet-2366	334	3	zeta	zeta	NOUN
admet-2366	334	4	potential	potential	ADJ
admet-2366	334	5	value	value	NOUN
admet-2366	334	6	of	of	ADP
admet-2366	334	7	the	the	DET
admet-2366	334	8	uncoated	uncoated	ADJ
admet-2366	334	9	nanoliposomes	nanoliposome	NOUN
admet-2366	334	10	may	may	AUX
admet-2366	334	11	lead	lead	VERB
admet-2366	334	12	to	to	ADP
admet-2366	334	13	stability	stability	NOUN
admet-2366	334	14	problems	problem	NOUN
admet-2366	334	15	due	due	ADJ
admet-2366	334	16	to	to	ADP
admet-2366	334	17	the	the	DET
admet-2366	334	18	aggregation	aggregation	NOUN
admet-2366	334	19	of	of	ADP
admet-2366	334	20	particles	particle	NOUN
admet-2366	334	21	.	.	PUNCT
admet-2366	335	1	on	on	ADP
admet-2366	335	2	the	the	DET
admet-2366	335	3	other	other	ADJ
admet-2366	335	4	hand	hand	NOUN
admet-2366	335	5	,	,	PUNCT
admet-2366	335	6	the	the	DET
admet-2366	335	7	coated	coated	ADJ
admet-2366	335	8	formulation	formulation	NOUN
admet-2366	335	9	was	be	AUX
admet-2366	335	10	found	find	VERB
admet-2366	335	11	to	to	PART
admet-2366	335	12	be	be	AUX
admet-2366	335	13	stable	stable	ADJ
admet-2366	335	14	with	with	ADP
admet-2366	335	15	a	a	DET
admet-2366	335	16	high	high	ADJ
admet-2366	335	17	zeta	zeta	NOUN
admet-2366	335	18	potential	potential	ADJ
admet-2366	335	19	value	value	NOUN
admet-2366	335	20	.	.	PUNCT
admet-2366	336	1	the	the	DET
admet-2366	336	2	results	result	NOUN
admet-2366	336	3	showed	show	VERB
admet-2366	336	4	that	that	SCONJ
admet-2366	336	5	sonication	sonication	NOUN
admet-2366	336	6	duration	duration	NOUN
admet-2366	336	7	had	have	VERB
admet-2366	336	8	a	a	DET
admet-2366	336	9	favourable	favourable	ADJ
admet-2366	336	10	impact	impact	NOUN
admet-2366	336	11	on	on	ADP
admet-2366	336	12	particle	particle	NOUN
admet-2366	336	13	dimension	dimension	NOUN
admet-2366	336	14	,	,	PUNCT
admet-2366	336	15	whereas	whereas	SCONJ
admet-2366	336	16	the	the	DET
admet-2366	336	17	cholesterol	cholesterol	NOUN
admet-2366	336	18	/	/	SYM
admet-2366	336	19	soya	soya	NOUN
admet-2366	336	20	lecithin	lecithin	NOUN
admet-2366	336	21	and	and	CCONJ
admet-2366	336	22	tween	tween	NOUN
admet-2366	336	23	80	80	NUM
admet-2366	336	24	/	/	SYM
admet-2366	336	25	soya	soya	NOUN
admet-2366	336	26	lecithin	lecithin	NOUN
admet-2366	336	27	ratios	ratio	NOUN
admet-2366	336	28	had	have	VERB
admet-2366	336	29	a	a	DET
admet-2366	336	30	negative	negative	ADJ
admet-2366	336	31	impact	impact	NOUN
admet-2366	336	32	.	.	PUNCT
admet-2366	337	1	to	to	PART
admet-2366	337	2	determine	determine	VERB
admet-2366	337	3	the	the	DET
admet-2366	337	4	melting	melting	NOUN
admet-2366	337	5	point	point	NOUN
admet-2366	337	6	and	and	CCONJ
admet-2366	337	7	confirm	confirm	VERB
admet-2366	337	8	drug	drug	NOUN
admet-2366	337	9	encapsulation	encapsulation	NOUN
admet-2366	337	10	in	in	ADP
admet-2366	337	11	the	the	DET
admet-2366	337	12	nanoliposomal	nanoliposomal	ADJ
admet-2366	337	13	formulation	formulation	NOUN
admet-2366	337	14	before	before	ADV
admet-2366	337	15	and	and	CCONJ
admet-2366	337	16	after	after	ADP
admet-2366	337	17	coating	coating	NOUN
admet-2366	337	18	,	,	PUNCT
admet-2366	337	19	thermal	thermal	ADJ
admet-2366	337	20	analysis	analysis	NOUN
admet-2366	337	21	of	of	ADP
admet-2366	337	22	gefitinib	gefitinib	NOUN
admet-2366	337	23	,	,	PUNCT
admet-2366	337	24	chitosan	chitosan	NOUN
admet-2366	337	25	,	,	PUNCT
admet-2366	337	26	cholesterol	cholesterol	NOUN
admet-2366	337	27	,	,	PUNCT
admet-2366	337	28	soya	soya	NOUN
admet-2366	337	29	lecithin	lecithin	NOUN
admet-2366	337	30	,	,	PUNCT
admet-2366	337	31	uncoated	uncoated	ADJ
admet-2366	337	32	nanoliposomal	nanoliposomal	NOUN
admet-2366	337	33	,	,	PUNCT
admet-2366	337	34	and	and	CCONJ
admet-2366	337	35	coated	coated	ADJ
admet-2366	337	36	nanoliposomal	nanoliposomal	NOUN
admet-2366	337	37	was	be	AUX
admet-2366	337	38	carried	carry	VERB
admet-2366	337	39	out	out	ADP
admet-2366	337	40	using	use	VERB
admet-2366	337	41	a	a	DET
admet-2366	337	42	dsc	dsc	NOUN
admet-2366	337	43	instrument	instrument	NOUN
admet-2366	337	44	(	(	PUNCT
admet-2366	337	45	q	q	PROPN
admet-2366	337	46	10	10	NUM
admet-2366	337	47	,	,	PUNCT
admet-2366	337	48	ta	ta	ADP
admet-2366	337	49	instruments	instrument	NOUN
admet-2366	337	50	,	,	PUNCT
admet-2366	337	51	new	new	ADJ
admet-2366	337	52	castle	castle	NOUN
admet-2366	337	53	,	,	PUNCT
admet-2366	337	54	united	united	PROPN
admet-2366	337	55	states	states	PROPN
admet-2366	337	56	)	)	PUNCT
admet-2366	337	57	.	.	PUNCT
admet-2366	338	1	the	the	DET
admet-2366	338	2	lack	lack	NOUN
admet-2366	338	3	of	of	ADP
admet-2366	338	4	an	an	DET
admet-2366	338	5	endothermic	endothermic	ADJ
admet-2366	338	6	peak	peak	NOUN
admet-2366	338	7	of	of	ADP
admet-2366	338	8	the	the	DET
admet-2366	338	9	drug	drug	NOUN
admet-2366	338	10	in	in	ADP
admet-2366	338	11	the	the	DET
admet-2366	338	12	thermogram	thermogram	NOUN
admet-2366	338	13	of	of	ADP
admet-2366	338	14	formulation	formulation	NOUN
admet-2366	338	15	indicated	indicate	VERB
admet-2366	338	16	that	that	SCONJ
admet-2366	338	17	the	the	DET
admet-2366	338	18	drug	drug	NOUN
admet-2366	338	19	might	might	AUX
admet-2366	338	20	form	form	VERB
admet-2366	338	21	an	an	DET
admet-2366	338	22	amorphous	amorphous	ADJ
admet-2366	338	23	form	form	NOUN
admet-2366	338	24	,	,	PUNCT
admet-2366	338	25	disperse	disperse	NOUN
admet-2366	338	26	,	,	PUNCT
admet-2366	338	27	or	or	CCONJ
admet-2366	338	28	liquefy	liquefy	VERB
admet-2366	338	29	in	in	ADP
admet-2366	338	30	the	the	DET
admet-2366	338	31	polymer	polymer	NOUN
admet-2366	338	32	medium	medium	NOUN
admet-2366	338	33	during	during	ADP
admet-2366	338	34	the	the	DET
admet-2366	338	35	production	production	NOUN
admet-2366	338	36	of	of	ADP
admet-2366	338	37	nanoliposomes	nanoliposome	NOUN
admet-2366	338	38	.	.	PUNCT
admet-2366	339	1	it	it	PRON
admet-2366	339	2	confirmed	confirm	VERB
admet-2366	339	3	the	the	DET
admet-2366	339	4	incorporation	incorporation	NOUN
admet-2366	339	5	of	of	ADP
admet-2366	339	6	the	the	DET
admet-2366	339	7	drug	drug	NOUN
admet-2366	339	8	as	as	ADP
admet-2366	339	9	a	a	DET
admet-2366	339	10	molecular	molecular	ADJ
admet-2366	339	11	dispersal	dispersal	NOUN
admet-2366	339	12	within	within	ADP
admet-2366	339	13	the	the	DET
admet-2366	339	14	nanoliposomes	nanoliposome	NOUN
admet-2366	339	15	.	.	PUNCT
admet-2366	340	1	the	the	DET
admet-2366	340	2	endothermic	endothermic	PROPN
admet-2366	340	3	peak	peak	NOUN
admet-2366	340	4	in	in	ADP
admet-2366	340	5	the	the	DET
admet-2366	340	6	case	case	NOUN
admet-2366	340	7	of	of	ADP
admet-2366	340	8	surface	surface	NOUN
admet-2366	340	9	-	-	PUNCT
admet-2366	340	10	adorned	adorn	VERB
admet-2366	340	11	nanoliposomes	nanoliposome	NOUN
admet-2366	340	12	close	close	ADV
admet-2366	340	13	to	to	ADP
admet-2366	340	14	the	the	DET
admet-2366	340	15	chitosan	chitosan	ADJ
admet-2366	340	16	liquefaction	liquefaction	NOUN
admet-2366	340	17	range	range	NOUN
admet-2366	340	18	confirmed	confirm	VERB
admet-2366	340	19	the	the	DET
admet-2366	340	20	coating	coating	NOUN
admet-2366	340	21	of	of	ADP
admet-2366	340	22	nanoliposomes	nanoliposome	NOUN
admet-2366	340	23	by	by	ADP
admet-2366	340	24	the	the	DET
admet-2366	340	25	chitosan	chitosan	NOUN
admet-2366	340	26	.	.	PUNCT
admet-2366	341	1	ft	ft	X
admet-2366	341	2	-	-	PUNCT
admet-2366	341	3	ir	ir	PROPN
admet-2366	341	4	spectroscopy	spectroscopy	NOUN
admet-2366	341	5	was	be	AUX
admet-2366	341	6	used	use	VERB
admet-2366	341	7	to	to	PART
admet-2366	341	8	investigate	investigate	VERB
admet-2366	341	9	drug	drug	NOUN
admet-2366	341	10	excipient	excipient	ADJ
admet-2366	341	11	compatibility	compatibility	NOUN
admet-2366	341	12	.	.	PUNCT
admet-2366	342	1	the	the	DET
admet-2366	342	2	frequency	frequency	NOUN
admet-2366	342	3	and	and	CCONJ
admet-2366	342	4	bandwidth	bandwidth	NOUN
admet-2366	342	5	of	of	ADP
admet-2366	342	6	various	various	ADJ
admet-2366	342	7	functional	functional	ADJ
admet-2366	342	8	groups	group	NOUN
admet-2366	342	9	were	be	AUX
admet-2366	342	10	investigated	investigate	VERB
admet-2366	342	11	using	use	VERB
admet-2366	342	12	ft	ft	PROPN
admet-2366	342	13	-	-	PUNCT
admet-2366	342	14	ir	ir	NOUN
admet-2366	342	15	spectroscopy	spectroscopy	NOUN
admet-2366	342	16	to	to	PART
admet-2366	342	17	investigate	investigate	VERB
admet-2366	342	18	even	even	ADV
admet-2366	342	19	minor	minor	ADJ
admet-2366	342	20	changes	change	NOUN
admet-2366	342	21	in	in	ADP
admet-2366	342	22	the	the	DET
admet-2366	342	23	structural	structural	ADJ
admet-2366	342	24	configurations	configuration	NOUN
admet-2366	342	25	of	of	ADP
admet-2366	342	26	the	the	DET
admet-2366	342	27	lipid	lipid	NOUN
admet-2366	342	28	assemblies	assembly	NOUN
admet-2366	342	29	.	.	PUNCT
admet-2366	343	1	the	the	DET
admet-2366	343	2	functional	functional	ADJ
admet-2366	343	3	moieties	moiety	NOUN
admet-2366	343	4	on	on	ADP
admet-2366	343	5	acyl	acyl	NOUN
admet-2366	343	6	chains	chain	NOUN
admet-2366	343	7	and	and	CCONJ
admet-2366	343	8	lipid	lipid	NOUN
admet-2366	343	9	molecules	molecule	NOUN
admet-2366	343	10	were	be	AUX
admet-2366	343	11	studied	study	VERB
admet-2366	343	12	to	to	PART
admet-2366	343	13	investigate	investigate	VERB
admet-2366	343	14	the	the	DET
admet-2366	343	15	arrangement	arrangement	NOUN
admet-2366	343	16	aspect	aspect	NOUN
admet-2366	343	17	of	of	ADP
admet-2366	343	18	the	the	DET
admet-2366	343	19	lipid	lipid	NOUN
admet-2366	343	20	molecules	molecule	NOUN
admet-2366	343	21	in	in	ADP
admet-2366	343	22	the	the	DET
admet-2366	343	23	presence	presence	NOUN
admet-2366	343	24	or	or	CCONJ
admet-2366	343	25	absence	absence	NOUN
admet-2366	343	26	of	of	ADP
admet-2366	343	27	the	the	DET
admet-2366	343	28	chitosan	chitosan	ADJ
admet-2366	343	29	moiety	moiety	NOUN
admet-2366	343	30	.	.	PUNCT
admet-2366	344	1	the	the	DET
admet-2366	344	2	results	result	NOUN
admet-2366	344	3	suggested	suggest	VERB
admet-2366	344	4	that	that	SCONJ
admet-2366	344	5	the	the	DET
admet-2366	344	6	drug	drug	NOUN
admet-2366	344	7	be	be	AUX
admet-2366	344	8	stable	stable	ADJ
admet-2366	344	9	throughout	throughout	ADP
admet-2366	344	10	the	the	DET
admet-2366	344	11	encapsulation	encapsulation	NOUN
admet-2366	344	12	process	process	NOUN
admet-2366	344	13	[	[	X
admet-2366	344	14	53	53	NUM
admet-2366	344	15	]	]	PUNCT
admet-2366	344	16	.	.	PUNCT
admet-2366	345	1	tem	tem	PROPN
admet-2366	345	2	image	image	NOUN
admet-2366	345	3	at	at	ADP
admet-2366	345	4	a	a	DET
admet-2366	345	5	scale	scale	NOUN
admet-2366	345	6	bar	bar	NOUN
admet-2366	345	7	of	of	ADP
admet-2366	345	8	50	50	NUM
admet-2366	345	9	nm	nm	NOUN
admet-2366	345	10	and	and	CCONJ
admet-2366	345	11	a	a	DET
admet-2366	345	12	magnification	magnification	NOUN
admet-2366	345	13	of	of	ADP
admet-2366	345	14	200	200	NUM
admet-2366	345	15	kv	kv	NOUN
admet-2366	345	16	confirmed	confirm	VERB
admet-2366	345	17	the	the	DET
admet-2366	345	18	coating	coating	NOUN
admet-2366	345	19	of	of	ADP
admet-2366	345	20	chitosan	chitosan	NOUN
admet-2366	345	21	on	on	ADP
admet-2366	345	22	the	the	DET
admet-2366	345	23	surface	surface	NOUN
admet-2366	345	24	of	of	ADP
admet-2366	345	25	nanoliposomes	nanoliposome	NOUN
admet-2366	345	26	.	.	PUNCT
admet-2366	346	1	percentage	percentage	NOUN
admet-2366	346	2	cumulative	cumulative	ADJ
admet-2366	346	3	drug	drug	NOUN
admet-2366	346	4	release	release	NOUN
admet-2366	346	5	studies	study	NOUN
admet-2366	346	6	of	of	ADP
admet-2366	346	7	optimised	optimise	VERB
admet-2366	346	8	uncoated	uncoated	ADJ
admet-2366	346	9	(	(	PUNCT
admet-2366	346	10	ng13	ng13	PROPN
admet-2366	346	11	)	)	PUNCT
admet-2366	346	12	and	and	CCONJ
admet-2366	346	13	surface	surface	NOUN
admet-2366	346	14	-	-	PUNCT
admet-2366	346	15	adorned	adorn	VERB
admet-2366	346	16	nanoliposomal	nanoliposomal	ADJ
admet-2366	346	17	formulations	formulation	NOUN
admet-2366	346	18	were	be	AUX
admet-2366	346	19	conducted	conduct	VERB
admet-2366	346	20	in	in	ADP
admet-2366	346	21	three	three	NUM
admet-2366	346	22	different	different	ADJ
admet-2366	346	23	mediums	medium	NOUN
admet-2366	346	24	for	for	ADP
admet-2366	346	25	24	24	NUM
admet-2366	346	26	h	h	NOUN
admet-2366	346	27	in	in	ADP
admet-2366	346	28	simulated	simulated	ADJ
admet-2366	346	29	gastrointestinal	gastrointestinal	ADJ
admet-2366	346	30	fluid	fluid	NOUN
admet-2366	346	31	(	(	PUNCT
admet-2366	346	32	ph	ph	NOUN
admet-2366	346	33	1.2	1.2	NUM
admet-2366	346	34	)	)	PUNCT
admet-2366	346	35	,	,	PUNCT
admet-2366	346	36	acetate	acetate	NOUN
admet-2366	346	37	buffer	buffer	NOUN
admet-2366	346	38	(	(	PUNCT
admet-2366	346	39	ph	ph	NOUN
admet-2366	346	40	4.0	4.0	NUM
admet-2366	346	41	)	)	PUNCT
admet-2366	346	42	,	,	PUNCT
admet-2366	346	43	and	and	CCONJ
admet-2366	346	44	simulated	simulate	VERB
admet-2366	346	45	intestinal	intestinal	ADJ
admet-2366	346	46	fluid	fluid	NOUN
admet-2366	346	47	(	(	PUNCT
admet-2366	346	48	ph	ph	NOUN
admet-2366	346	49	6.8	6.8	NUM
admet-2366	346	50	)	)	PUNCT
admet-2366	346	51	.	.	PUNCT
admet-2366	347	1	slow	slow	ADJ
admet-2366	347	2	drug	drug	NOUN
admet-2366	347	3	release	release	NOUN
admet-2366	347	4	up	up	ADP
admet-2366	347	5	to	to	PART
admet-2366	347	6	5	5	NUM
admet-2366	347	7	h	h	NOUN
admet-2366	347	8	may	may	AUX
admet-2366	347	9	be	be	AUX
admet-2366	347	10	due	due	ADJ
admet-2366	347	11	to	to	ADP
admet-2366	347	12	a	a	DET
admet-2366	347	13	delay	delay	NOUN
admet-2366	347	14	in	in	ADP
admet-2366	347	15	the	the	DET
admet-2366	347	16	formation	formation	NOUN
admet-2366	347	17	of	of	ADP
admet-2366	347	18	the	the	DET
admet-2366	347	19	hydrated	hydrated	ADJ
admet-2366	347	20	dormant	dormant	ADJ
admet-2366	347	21	layer	layer	NOUN
admet-2366	347	22	by	by	ADP
admet-2366	347	23	the	the	DET
admet-2366	347	24	external	external	ADJ
admet-2366	347	25	shield	shield	NOUN
admet-2366	347	26	polymer	polymer	NOUN
admet-2366	347	27	or	or	CCONJ
admet-2366	347	28	to	to	PART
admet-2366	347	29	slow	slow	VERB
admet-2366	347	30	drug	drug	NOUN
admet-2366	347	31	diffusion	diffusion	NOUN
admet-2366	347	32	from	from	ADP
admet-2366	347	33	the	the	DET
admet-2366	347	34	stagnant	stagnant	ADJ
admet-2366	347	35	layer	layer	NOUN
admet-2366	347	36	of	of	ADP
admet-2366	347	37	the	the	DET
admet-2366	347	38	external	external	ADJ
admet-2366	347	39	shell	shell	NOUN
admet-2366	347	40	polymer	polymer	NOUN
admet-2366	347	41	.	.	PUNCT
admet-2366	348	1	it	it	PRON
admet-2366	348	2	is	be	AUX
admet-2366	348	3	confirmed	confirm	VERB
admet-2366	348	4	that	that	SCONJ
admet-2366	348	5	the	the	DET
admet-2366	348	6	drug	drug	NOUN
admet-2366	348	7	is	be	AUX
admet-2366	348	8	entrapped	entrap	VERB
admet-2366	348	9	in	in	ADP
admet-2366	348	10	the	the	DET
admet-2366	348	11	core	core	NOUN
admet-2366	348	12	nanoliposomes	nanoliposome	NOUN
admet-2366	348	13	.	.	PUNCT
admet-2366	349	1	it	it	PRON
admet-2366	349	2	confirmed	confirm	VERB
admet-2366	349	3	the	the	DET
admet-2366	349	4	stable	stable	ADJ
admet-2366	349	5	incorporation	incorporation	NOUN
admet-2366	349	6	of	of	ADP
admet-2366	349	7	drugs	drug	NOUN
admet-2366	349	8	in	in	ADP
admet-2366	349	9	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PROPN
admet-2366	349	10	s.	s.	PROPN
admet-2366	349	11	rohilla	rohilla	PROPN
admet-2366	349	12	et	et	PROPN
admet-2366	349	13	al	al	PROPN
admet-2366	349	14	.	.	PROPN
admet-2366	349	15	admet	admet	PROPN
admet-2366	349	16	&	&	CCONJ
admet-2366	349	17	dmpk	dmpk	PROPN
admet-2366	349	18	12(4	12(4	PROPN
admet-2366	349	19	)	)	PUNCT
admet-2366	349	20	(	(	PUNCT
admet-2366	349	21	2024	2024	NUM
admet-2366	349	22	)	)	PUNCT
admet-2366	349	23	657	657	NUM
admet-2366	349	24	-	-	SYM
admet-2366	349	25	677	677	NUM
admet-2366	349	26	672	672	NUM
admet-2366	349	27	formulations	formulation	NOUN
admet-2366	349	28	,	,	PUNCT
admet-2366	349	29	which	which	PRON
admet-2366	349	30	might	might	AUX
admet-2366	349	31	help	help	VERB
admet-2366	349	32	minimize	minimize	VERB
admet-2366	349	33	the	the	DET
admet-2366	349	34	side	side	NOUN
admet-2366	349	35	effects	effect	NOUN
admet-2366	349	36	of	of	ADP
admet-2366	349	37	drugs	drug	NOUN
admet-2366	349	38	and	and	CCONJ
admet-2366	349	39	improve	improve	VERB
admet-2366	349	40	the	the	DET
admet-2366	349	41	therapeutic	therapeutic	ADJ
admet-2366	349	42	index	index	NOUN
admet-2366	349	43	of	of	ADP
admet-2366	349	44	drugs	drug	NOUN
admet-2366	349	45	.	.	PUNCT
admet-2366	350	1	it	it	PRON
admet-2366	350	2	is	be	AUX
admet-2366	350	3	clear	clear	ADJ
admet-2366	350	4	from	from	ADP
admet-2366	350	5	the	the	DET
admet-2366	350	6	results	result	NOUN
admet-2366	350	7	that	that	SCONJ
admet-2366	350	8	the	the	DET
admet-2366	350	9	release	release	NOUN
admet-2366	350	10	of	of	ADP
admet-2366	350	11	drug	drug	NOUN
admet-2366	350	12	from	from	ADP
admet-2366	350	13	nanoliposomes	nanoliposome	NOUN
admet-2366	350	14	was	be	AUX
admet-2366	350	15	reduced	reduce	VERB
admet-2366	350	16	after	after	ADP
admet-2366	350	17	coating	coat	VERB
admet-2366	350	18	with	with	ADP
admet-2366	350	19	chitosan	chitosan	NOUN
admet-2366	350	20	at	at	ADP
admet-2366	350	21	all	all	DET
admet-2366	350	22	examined	examine	VERB
admet-2366	350	23	intervals	interval	NOUN
admet-2366	350	24	in	in	ADP
admet-2366	350	25	all	all	DET
admet-2366	350	26	three	three	NUM
admet-2366	350	27	media	medium	NOUN
admet-2366	350	28	.	.	PUNCT
admet-2366	351	1	gefitinib	gefitinib	NOUN
admet-2366	351	2	release	release	NOUN
admet-2366	351	3	was	be	AUX
admet-2366	351	4	found	find	VERB
admet-2366	351	5	to	to	PART
admet-2366	351	6	be	be	AUX
admet-2366	351	7	highest	high	ADJ
admet-2366	351	8	in	in	ADP
admet-2366	351	9	simulated	simulated	ADJ
admet-2366	351	10	gastrointestinal	gastrointestinal	ADJ
admet-2366	351	11	fluid	fluid	NOUN
admet-2366	351	12	because	because	SCONJ
admet-2366	351	13	its	its	PRON
admet-2366	351	14	basic	basic	ADJ
admet-2366	351	15	nature	nature	NOUN
admet-2366	351	16	makes	make	VERB
admet-2366	351	17	it	it	PRON
admet-2366	351	18	more	more	ADV
admet-2366	351	19	likely	likely	ADJ
admet-2366	351	20	to	to	PART
admet-2366	351	21	dissolve	dissolve	VERB
admet-2366	351	22	in	in	ADP
admet-2366	351	23	an	an	DET
admet-2366	351	24	acidic	acidic	ADJ
admet-2366	351	25	medium	medium	NOUN
admet-2366	351	26	.	.	PUNCT
admet-2366	352	1	the	the	DET
admet-2366	352	2	controlled	control	VERB
admet-2366	352	3	release	release	NOUN
admet-2366	352	4	of	of	ADP
admet-2366	352	5	the	the	DET
admet-2366	352	6	drug	drug	NOUN
admet-2366	352	7	from	from	ADP
admet-2366	352	8	nanoliposomes	nanoliposome	NOUN
admet-2366	352	9	in	in	ADP
admet-2366	352	10	the	the	DET
admet-2366	352	11	simulated	simulate	VERB
admet-2366	352	12	gastrointestinal	gastrointestinal	ADJ
admet-2366	352	13	fluid	fluid	NOUN
admet-2366	352	14	may	may	AUX
admet-2366	352	15	extend	extend	VERB
admet-2366	352	16	its	its	PRON
admet-2366	352	17	absorption	absorption	NOUN
admet-2366	352	18	time	time	NOUN
admet-2366	352	19	,	,	PUNCT
admet-2366	352	20	which	which	PRON
admet-2366	352	21	might	might	AUX
admet-2366	352	22	be	be	AUX
admet-2366	352	23	beneficial	beneficial	ADJ
admet-2366	352	24	in	in	ADP
admet-2366	352	25	enhancing	enhance	VERB
admet-2366	352	26	the	the	DET
admet-2366	352	27	therapeutic	therapeutic	ADJ
admet-2366	352	28	index	index	NOUN
admet-2366	352	29	of	of	ADP
admet-2366	352	30	the	the	DET
admet-2366	352	31	drug	drug	NOUN
admet-2366	352	32	and	and	CCONJ
admet-2366	352	33	reducing	reduce	VERB
admet-2366	352	34	its	its	PRON
admet-2366	352	35	associated	associated	ADJ
admet-2366	352	36	side	side	NOUN
admet-2366	352	37	effects	effect	NOUN
admet-2366	352	38	.	.	PUNCT
admet-2366	353	1	to	to	PART
admet-2366	353	2	recognize	recognize	VERB
admet-2366	353	3	the	the	DET
admet-2366	353	4	kinetics	kinetic	NOUN
admet-2366	353	5	and	and	CCONJ
admet-2366	353	6	mode	mode	NOUN
admet-2366	353	7	of	of	ADP
admet-2366	353	8	drug	drug	NOUN
admet-2366	353	9	liberation	liberation	NOUN
admet-2366	353	10	from	from	ADP
admet-2366	353	11	nanovesicles	nanovesicle	NOUN
admet-2366	353	12	,	,	PUNCT
admet-2366	353	13	the	the	DET
admet-2366	353	14	data	datum	NOUN
admet-2366	353	15	obtained	obtain	VERB
admet-2366	353	16	from	from	ADP
admet-2366	353	17	the	the	DET
admet-2366	353	18	study	study	NOUN
admet-2366	353	19	of	of	ADP
admet-2366	353	20	in	in	ADP
admet-2366	353	21	vitro	vitro	X
admet-2366	353	22	release	release	NOUN
admet-2366	353	23	was	be	AUX
admet-2366	353	24	integrated	integrate	VERB
admet-2366	353	25	into	into	ADP
admet-2366	353	26	different	different	ADJ
admet-2366	353	27	kinetic	kinetic	ADJ
admet-2366	353	28	equations	equation	NOUN
admet-2366	353	29	.	.	PUNCT
admet-2366	354	1	a	a	DET
admet-2366	354	2	kinetic	kinetic	ADJ
admet-2366	354	3	study	study	NOUN
admet-2366	354	4	of	of	ADP
admet-2366	354	5	in	in	ADP
admet-2366	354	6	vitro	vitro	X
admet-2366	354	7	drug	drug	NOUN
admet-2366	354	8	release	release	NOUN
admet-2366	354	9	data	datum	NOUN
admet-2366	354	10	demonstrated	demonstrate	VERB
admet-2366	354	11	that	that	SCONJ
admet-2366	354	12	the	the	DET
admet-2366	354	13	drug	drug	NOUN
admet-2366	354	14	acted	act	VERB
admet-2366	354	15	in	in	ADP
admet-2366	354	16	accordance	accordance	NOUN
admet-2366	354	17	with	with	ADP
admet-2366	354	18	fickian	fickian	ADJ
admet-2366	354	19	-	-	PUNCT
admet-2366	354	20	type	type	NOUN
admet-2366	354	21	diffusion	diffusion	NOUN
admet-2366	354	22	(	(	PUNCT
admet-2366	354	23	n	n	CCONJ
admet-2366	354	24	<	<	X
admet-2366	354	25	0.5	0.5	NUM
admet-2366	354	26	)	)	PUNCT
admet-2366	354	27	in	in	ADP
admet-2366	354	28	both	both	DET
admet-2366	354	29	cases	case	NOUN
admet-2366	354	30	.	.	PUNCT
admet-2366	355	1	based	base	VERB
admet-2366	355	2	on	on	ADP
admet-2366	355	3	the	the	DET
admet-2366	355	4	value	value	NOUN
admet-2366	355	5	of	of	ADP
admet-2366	355	6	"	"	PUNCT
admet-2366	355	7	n	n	CCONJ
admet-2366	355	8	"	"	PUNCT
admet-2366	355	9	,	,	PUNCT
admet-2366	355	10	it	it	PRON
admet-2366	355	11	was	be	AUX
admet-2366	355	12	found	find	VERB
admet-2366	355	13	that	that	SCONJ
admet-2366	355	14	in	in	ADP
admet-2366	355	15	both	both	DET
admet-2366	355	16	cases	case	NOUN
admet-2366	355	17	,	,	PUNCT
admet-2366	355	18	the	the	DET
admet-2366	355	19	drug	drug	NOUN
admet-2366	355	20	follows	follow	VERB
admet-2366	355	21	the	the	DET
admet-2366	355	22	fickian	fickian	ADJ
admet-2366	355	23	law	law	NOUN
admet-2366	355	24	of	of	ADP
admet-2366	355	25	diffusion	diffusion	NOUN
admet-2366	355	26	and	and	CCONJ
admet-2366	355	27	diffuses	diffuse	NOUN
admet-2366	355	28	from	from	ADP
admet-2366	355	29	higher	high	ADJ
admet-2366	355	30	concentrations	concentration	NOUN
admet-2366	355	31	to	to	PART
admet-2366	355	32	lower	low	ADJ
admet-2366	355	33	concentrations	concentration	NOUN
admet-2366	355	34	.	.	PUNCT
admet-2366	356	1	it	it	PRON
admet-2366	356	2	means	mean	VERB
admet-2366	356	3	that	that	SCONJ
admet-2366	356	4	gefitinib	gefitinib	NOUN
admet-2366	356	5	was	be	AUX
admet-2366	356	6	liberated	liberate	VERB
admet-2366	356	7	from	from	ADP
admet-2366	356	8	the	the	DET
admet-2366	356	9	nanoliposomes	nanoliposome	NOUN
admet-2366	356	10	by	by	ADP
admet-2366	356	11	diffusion	diffusion	NOUN
admet-2366	356	12	mechanism	mechanism	NOUN
admet-2366	356	13	,	,	PUNCT
admet-2366	356	14	i.e.	i.e.	X
admet-2366	356	15	,	,	PUNCT
admet-2366	356	16	the	the	DET
admet-2366	356	17	solvent	solvent	NOUN
admet-2366	356	18	penetrated	penetrate	VERB
admet-2366	356	19	the	the	DET
admet-2366	356	20	polymer	polymer	NOUN
admet-2366	356	21	matrix	matrix	NOUN
admet-2366	356	22	and	and	CCONJ
admet-2366	356	23	caused	cause	VERB
admet-2366	356	24	swelling	swelling	NOUN
admet-2366	356	25	,	,	PUNCT
admet-2366	356	26	ultimately	ultimately	ADV
admet-2366	356	27	leading	lead	VERB
admet-2366	356	28	to	to	ADP
admet-2366	356	29	polymer	polymer	NOUN
admet-2366	356	30	chain	chain	NOUN
admet-2366	356	31	disentanglement	disentanglement	NOUN
admet-2366	356	32	that	that	PRON
admet-2366	356	33	relaxed	relax	VERB
admet-2366	356	34	the	the	DET
admet-2366	356	35	polymer	polymer	NOUN
admet-2366	356	36	matrix	matrix	NOUN
admet-2366	356	37	and	and	CCONJ
admet-2366	356	38	liberated	liberate	VERB
admet-2366	356	39	the	the	DET
admet-2366	356	40	drug	drug	NOUN
admet-2366	356	41	by	by	ADP
admet-2366	356	42	diffusion	diffusion	NOUN
admet-2366	356	43	mechanism	mechanism	NOUN
admet-2366	356	44	.	.	PUNCT
admet-2366	357	1	thus	thus	ADV
admet-2366	357	2	,	,	PUNCT
admet-2366	357	3	the	the	DET
admet-2366	357	4	polymer	polymer	NOUN
admet-2366	357	5	chain	chain	NOUN
admet-2366	357	6	relaxation	relaxation	NOUN
admet-2366	357	7	and	and	CCONJ
admet-2366	357	8	extrication	extrication	NOUN
admet-2366	357	9	regulated	regulate	VERB
admet-2366	357	10	the	the	DET
admet-2366	357	11	release	release	NOUN
admet-2366	357	12	of	of	ADP
admet-2366	357	13	drugs	drug	NOUN
admet-2366	357	14	from	from	ADP
admet-2366	357	15	nanovesicles	nanovesicle	NOUN
admet-2366	357	16	;	;	PUNCT
admet-2366	357	17	it	it	PRON
admet-2366	357	18	confirmed	confirm	VERB
admet-2366	357	19	that	that	SCONJ
admet-2366	357	20	both	both	DET
admet-2366	357	21	processes	process	NOUN
admet-2366	357	22	,	,	PUNCT
admet-2366	357	23	like	like	ADP
admet-2366	357	24	swelling	swelling	NOUN
admet-2366	357	25	and	and	CCONJ
admet-2366	357	26	solvent	solvent	ADJ
admet-2366	357	27	penetration	penetration	NOUN
admet-2366	357	28	,	,	PUNCT
admet-2366	357	29	run	run	VERB
admet-2366	357	30	concurrently	concurrently	ADV
admet-2366	357	31	at	at	ADP
admet-2366	357	32	the	the	DET
admet-2366	357	33	same	same	ADJ
admet-2366	357	34	rates	rate	NOUN
admet-2366	357	35	.	.	PUNCT
admet-2366	358	1	the	the	DET
admet-2366	358	2	mtt	mtt	NOUN
admet-2366	358	3	assay	assay	VERB
admet-2366	358	4	was	be	AUX
admet-2366	358	5	used	use	VERB
admet-2366	358	6	to	to	PART
admet-2366	358	7	conduct	conduct	VERB
admet-2366	358	8	cytostatic	cytostatic	ADJ
admet-2366	358	9	studies	study	NOUN
admet-2366	358	10	of	of	ADP
admet-2366	358	11	gefitinib	gefitinib	NOUN
admet-2366	358	12	and	and	CCONJ
admet-2366	358	13	uncoated	uncoated	ADJ
admet-2366	358	14	and	and	CCONJ
admet-2366	358	15	surface	surface	NOUN
admet-2366	358	16	-	-	PUNCT
admet-2366	358	17	adorned	adorn	VERB
admet-2366	358	18	nanoliposomes	nanoliposome	NOUN
admet-2366	358	19	on	on	ADP
admet-2366	358	20	a549	a549	PROPN
admet-2366	358	21	and	and	CCONJ
admet-2366	358	22	h1299	h1299	NOUN
admet-2366	358	23	cells	cell	NOUN
admet-2366	358	24	.	.	PUNCT
admet-2366	359	1	mtt	mtt	PROPN
admet-2366	359	2	assay	assay	PROPN
admet-2366	359	3	findings	finding	NOUN
admet-2366	359	4	showed	show	VERB
admet-2366	359	5	that	that	SCONJ
admet-2366	359	6	a	a	DET
admet-2366	359	7	pure	pure	ADJ
admet-2366	359	8	free	free	ADJ
admet-2366	359	9	drug	drug	NOUN
admet-2366	359	10	was	be	AUX
admet-2366	359	11	more	more	ADV
admet-2366	359	12	effective	effective	ADJ
admet-2366	359	13	against	against	ADP
admet-2366	359	14	cells	cell	NOUN
admet-2366	359	15	than	than	ADP
admet-2366	359	16	an	an	DET
admet-2366	359	17	uncoated	uncoated	ADJ
admet-2366	359	18	or	or	CCONJ
admet-2366	359	19	chitosan	chitosan	NOUN
admet-2366	359	20	-	-	PUNCT
admet-2366	359	21	encrusted	encrust	VERB
admet-2366	359	22	formulation	formulation	NOUN
admet-2366	359	23	.	.	PUNCT
admet-2366	360	1	the	the	DET
admet-2366	360	2	pure	pure	ADJ
admet-2366	360	3	-	-	PUNCT
admet-2366	360	4	free	free	ADJ
admet-2366	360	5	drug	drug	NOUN
admet-2366	360	6	is	be	AUX
admet-2366	360	7	more	more	ADV
admet-2366	360	8	toxic	toxic	ADJ
admet-2366	360	9	than	than	SCONJ
admet-2366	360	10	drugloaded	drugloade	VERB
admet-2366	360	11	nanoliposomes	nanoliposome	NOUN
admet-2366	360	12	in	in	ADP
admet-2366	360	13	h1299	h1299	NOUN
admet-2366	360	14	and	and	CCONJ
admet-2366	360	15	a549	a549	PROPN
admet-2366	360	16	cells	cell	NOUN
admet-2366	360	17	.	.	PUNCT
admet-2366	361	1	free	free	ADJ
admet-2366	361	2	gefitinib	gefitinib	NOUN
admet-2366	361	3	has	have	AUX
admet-2366	361	4	shown	show	VERB
admet-2366	361	5	more	more	ADJ
admet-2366	361	6	cytotoxicity	cytotoxicity	NOUN
admet-2366	361	7	than	than	SCONJ
admet-2366	361	8	gefitinibloaded	gefitinibloade	VERB
admet-2366	361	9	nanoliposomes	nanoliposome	NOUN
admet-2366	361	10	,	,	PUNCT
admet-2366	361	11	demonstrating	demonstrate	VERB
admet-2366	361	12	stable	stable	ADJ
admet-2366	361	13	encapsulation	encapsulation	NOUN
admet-2366	361	14	of	of	ADP
admet-2366	361	15	gefitinib	gefitinib	NOUN
admet-2366	361	16	by	by	ADP
admet-2366	361	17	nanoliposomes	nanoliposome	NOUN
admet-2366	361	18	.	.	PUNCT
admet-2366	362	1	the	the	DET
admet-2366	362	2	low	low	ADJ
admet-2366	362	3	cytotoxicity	cytotoxicity	NOUN
admet-2366	362	4	of	of	ADP
admet-2366	362	5	gefitinib	gefitinib	NOUN
admet-2366	362	6	-	-	PUNCT
admet-2366	362	7	loaded	load	VERB
admet-2366	362	8	nanoliposomes	nanoliposome	NOUN
admet-2366	362	9	might	might	AUX
admet-2366	362	10	be	be	AUX
admet-2366	362	11	due	due	ADJ
admet-2366	362	12	to	to	ADP
admet-2366	362	13	the	the	DET
admet-2366	362	14	sluggish	sluggish	ADJ
admet-2366	362	15	delivery	delivery	NOUN
admet-2366	362	16	of	of	ADP
admet-2366	362	17	the	the	DET
admet-2366	362	18	drug	drug	NOUN
admet-2366	362	19	from	from	ADP
admet-2366	362	20	the	the	DET
admet-2366	362	21	nanovesicles	nanovesicle	NOUN
admet-2366	362	22	,	,	PUNCT
admet-2366	362	23	which	which	PRON
admet-2366	362	24	might	might	AUX
admet-2366	362	25	be	be	AUX
admet-2366	362	26	beneficial	beneficial	ADJ
admet-2366	362	27	in	in	ADP
admet-2366	362	28	enhancing	enhance	VERB
admet-2366	362	29	the	the	DET
admet-2366	362	30	therapeutic	therapeutic	ADJ
admet-2366	362	31	index	index	NOUN
admet-2366	362	32	of	of	ADP
admet-2366	362	33	the	the	DET
admet-2366	362	34	drug	drug	NOUN
admet-2366	362	35	by	by	ADP
admet-2366	362	36	avoiding	avoid	VERB
admet-2366	362	37	the	the	DET
admet-2366	362	38	exposure	exposure	NOUN
admet-2366	362	39	of	of	ADP
admet-2366	362	40	a	a	DET
admet-2366	362	41	large	large	ADJ
admet-2366	362	42	quantity	quantity	NOUN
admet-2366	362	43	of	of	ADP
admet-2366	362	44	the	the	DET
admet-2366	362	45	drug	drug	NOUN
admet-2366	362	46	.	.	PUNCT
admet-2366	363	1	analogous	analogous	ADJ
admet-2366	363	2	interpretations	interpretation	NOUN
admet-2366	363	3	were	be	AUX
admet-2366	363	4	reported	report	VERB
admet-2366	363	5	by	by	ADP
admet-2366	363	6	cheng	cheng	PROPN
admet-2366	363	7	et	et	PROPN
admet-2366	363	8	al	al	PROPN
admet-2366	363	9	.	.	PUNCT
admet-2366	364	1	[	[	X
admet-2366	364	2	54	54	NUM
admet-2366	364	3	]	]	PUNCT
admet-2366	364	4	.	.	PUNCT
admet-2366	365	1	they	they	PRON
admet-2366	365	2	reported	report	VERB
admet-2366	365	3	that	that	SCONJ
admet-2366	365	4	the	the	DET
admet-2366	365	5	ic50	ic50	PROPN
admet-2366	365	6	value	value	NOUN
admet-2366	365	7	of	of	ADP
admet-2366	365	8	free	free	ADJ
admet-2366	365	9	cisplatin	cisplatin	NOUN
admet-2366	365	10	was	be	AUX
admet-2366	365	11	less	less	ADJ
admet-2366	365	12	than	than	ADP
admet-2366	365	13	that	that	PRON
admet-2366	365	14	of	of	ADP
admet-2366	365	15	cisplatin	cisplatin	NOUN
admet-2366	365	16	-	-	PUNCT
admet-2366	365	17	loaded	load	VERB
admet-2366	365	18	nanoparticles	nanoparticle	NOUN
admet-2366	365	19	.	.	PUNCT
admet-2366	366	1	zhou	zhou	PROPN
admet-2366	366	2	et	et	PROPN
admet-2366	366	3	al	al	PROPN
admet-2366	366	4	.	.	PROPN
admet-2366	366	5	demonstrated	demonstrate	VERB
admet-2366	366	6	the	the	DET
admet-2366	366	7	stable	stable	ADJ
admet-2366	366	8	sequestration	sequestration	NOUN
admet-2366	366	9	of	of	ADP
admet-2366	366	10	the	the	DET
admet-2366	366	11	drug	drug	NOUN
admet-2366	366	12	by	by	ADP
admet-2366	366	13	liposomal	liposomal	ADJ
admet-2366	366	14	formulation	formulation	NOUN
admet-2366	366	15	,	,	PUNCT
admet-2366	366	16	as	as	SCONJ
admet-2366	366	17	lgef	lgef	NOUN
admet-2366	366	18	-	-	PUNCT
admet-2366	366	19	hspc-2	hspc-2	NOUN
admet-2366	366	20	displayed	display	VERB
admet-2366	366	21	minimum	minimum	ADJ
admet-2366	366	22	cytotoxicity	cytotoxicity	NOUN
admet-2366	366	23	compared	compare	VERB
admet-2366	366	24	to	to	ADP
admet-2366	366	25	the	the	DET
admet-2366	366	26	free	free	ADJ
admet-2366	366	27	drug	drug	NOUN
admet-2366	366	28	[	[	X
admet-2366	366	29	55	55	NUM
admet-2366	366	30	]	]	PUNCT
admet-2366	366	31	.	.	PUNCT
admet-2366	367	1	these	these	DET
admet-2366	367	2	findings	finding	NOUN
admet-2366	367	3	could	could	AUX
admet-2366	367	4	help	help	VERB
admet-2366	367	5	protect	protect	VERB
admet-2366	367	6	cells	cell	NOUN
admet-2366	367	7	from	from	ADP
admet-2366	367	8	all	all	DET
admet-2366	367	9	drug	drug	NOUN
admet-2366	367	10	exposure	exposure	NOUN
admet-2366	367	11	and	and	CCONJ
admet-2366	367	12	improve	improve	VERB
admet-2366	367	13	the	the	DET
admet-2366	367	14	therapeutic	therapeutic	ADJ
admet-2366	367	15	index	index	NOUN
admet-2366	367	16	.	.	PUNCT
admet-2366	368	1	a	a	DET
admet-2366	368	2	higher	high	ADJ
admet-2366	368	3	zeta	zeta	NOUN
admet-2366	368	4	potential	potential	ADJ
admet-2366	368	5	value	value	NOUN
admet-2366	368	6	of	of	ADP
admet-2366	368	7	coated	coated	ADJ
admet-2366	368	8	formulations	formulation	NOUN
admet-2366	368	9	than	than	ADP
admet-2366	368	10	unadorned	unadorned	ADJ
admet-2366	368	11	formulations	formulation	NOUN
admet-2366	368	12	indicates	indicate	VERB
admet-2366	368	13	their	their	PRON
admet-2366	368	14	more	more	ADV
admet-2366	368	15	anti	anti	ADJ
admet-2366	368	16	-	-	ADJ
admet-2366	368	17	leukemic	leukemic	ADJ
admet-2366	368	18	effect	effect	NOUN
admet-2366	368	19	.	.	PUNCT
admet-2366	369	1	a	a	DET
admet-2366	369	2	higher	high	ADJ
admet-2366	369	3	value	value	NOUN
admet-2366	369	4	of	of	ADP
admet-2366	369	5	positive	positive	ADJ
admet-2366	369	6	zeta	zeta	NOUN
admet-2366	369	7	potential	potential	NOUN
admet-2366	369	8	facilitates	facilitate	VERB
admet-2366	369	9	stronger	strong	ADJ
admet-2366	369	10	interactions	interaction	NOUN
admet-2366	369	11	of	of	ADP
admet-2366	369	12	nanovesicles	nanovesicle	NOUN
admet-2366	369	13	with	with	ADP
admet-2366	369	14	tumour	tumour	ADJ
admet-2366	369	15	cell	cell	NOUN
admet-2366	369	16	membranes	membrane	NOUN
admet-2366	369	17	,	,	PUNCT
admet-2366	369	18	resulting	result	VERB
admet-2366	369	19	in	in	ADP
admet-2366	369	20	enhanced	enhanced	ADJ
admet-2366	369	21	cytotoxicity	cytotoxicity	NOUN
admet-2366	369	22	of	of	ADP
admet-2366	369	23	cancer	cancer	NOUN
admet-2366	369	24	cells	cell	NOUN
admet-2366	369	25	[	[	X
admet-2366	369	26	56	56	NUM
admet-2366	369	27	]	]	PUNCT
admet-2366	369	28	.	.	PUNCT
admet-2366	370	1	he	he	PRON
admet-2366	370	2	et	et	PROPN
admet-2366	370	3	al	al	PROPN
admet-2366	370	4	.	.	PUNCT
admet-2366	371	1	[	[	X
admet-2366	371	2	57	57	NUM
admet-2366	371	3	]	]	PUNCT
admet-2366	371	4	observed	observe	VERB
admet-2366	371	5	that	that	SCONJ
admet-2366	371	6	increased	increase	VERB
admet-2366	371	7	zeta	zeta	NOUN
admet-2366	371	8	-	-	PUNCT
admet-2366	371	9	potential	potential	ADJ
admet-2366	371	10	values	value	NOUN
admet-2366	371	11	of	of	ADP
admet-2366	371	12	carboxymethyl	carboxymethyl	NOUN
admet-2366	371	13	chitosan	chitosan	NOUN
admet-2366	371	14	-	-	PUNCT
admet-2366	371	15	attached	attach	VERB
admet-2366	371	16	methyl	methyl	NOUN
admet-2366	371	17	methacrylate	methacrylate	NOUN
admet-2366	371	18	nanoparticles	nanoparticle	NOUN
admet-2366	371	19	produced	produce	VERB
admet-2366	371	20	a	a	DET
admet-2366	371	21	considerable	considerable	ADJ
admet-2366	371	22	enhancement	enhancement	NOUN
admet-2366	371	23	in	in	ADP
admet-2366	371	24	the	the	DET
admet-2366	371	25	cellular	cellular	ADJ
admet-2366	371	26	uptake	uptake	NOUN
admet-2366	371	27	of	of	ADP
admet-2366	371	28	nanoparticles	nanoparticle	NOUN
admet-2366	371	29	in	in	ADP
admet-2366	371	30	murine	murine	ADJ
admet-2366	371	31	macrophage	macrophage	ADJ
admet-2366	371	32	cells	cell	NOUN
admet-2366	371	33	.	.	PUNCT
admet-2366	372	1	the	the	DET
admet-2366	372	2	stability	stability	NOUN
admet-2366	372	3	of	of	ADP
admet-2366	372	4	nanoliposomes	nanoliposome	NOUN
admet-2366	372	5	was	be	AUX
admet-2366	372	6	studied	study	VERB
admet-2366	372	7	at	at	ADP
admet-2366	372	8	different	different	ADJ
admet-2366	372	9	temperatures	temperature	NOUN
admet-2366	372	10	as	as	ADP
admet-2366	372	11	per	per	ADP
admet-2366	372	12	ich	ich	NOUN
admet-2366	372	13	guidelines	guideline	NOUN
admet-2366	372	14	to	to	PART
admet-2366	372	15	emulate	emulate	VERB
admet-2366	372	16	physiological	physiological	ADJ
admet-2366	372	17	surroundings	surrounding	NOUN
admet-2366	372	18	.	.	PUNCT
admet-2366	373	1	during	during	ADP
admet-2366	373	2	the	the	DET
admet-2366	373	3	first	first	ADJ
admet-2366	373	4	month	month	NOUN
admet-2366	373	5	,	,	PUNCT
admet-2366	373	6	batches	batch	VERB
admet-2366	373	7	with	with	ADP
admet-2366	373	8	surface	surface	NOUN
admet-2366	373	9	-	-	PUNCT
admet-2366	373	10	adorned	adorn	VERB
admet-2366	373	11	nanoliposomes	nanoliposome	NOUN
admet-2366	373	12	did	do	AUX
admet-2366	373	13	not	not	PART
admet-2366	373	14	illustrate	illustrate	VERB
admet-2366	373	15	any	any	DET
admet-2366	373	16	significant	significant	ADJ
admet-2366	373	17	variations	variation	NOUN
admet-2366	373	18	in	in	ADP
admet-2366	373	19	particle	particle	NOUN
admet-2366	373	20	dimension	dimension	NOUN
admet-2366	373	21	,	,	PUNCT
admet-2366	373	22	entrapment	entrapment	ADJ
admet-2366	373	23	efficiency	efficiency	NOUN
admet-2366	373	24	,	,	PUNCT
admet-2366	373	25	or	or	CCONJ
admet-2366	373	26	appearance	appearance	NOUN
admet-2366	373	27	.	.	PUNCT
admet-2366	374	1	after	after	ADP
admet-2366	374	2	2	2	NUM
admet-2366	374	3	months	month	NOUN
admet-2366	374	4	,	,	PUNCT
admet-2366	374	5	there	there	PRON
admet-2366	374	6	was	be	VERB
admet-2366	374	7	a	a	DET
admet-2366	374	8	significant	significant	ADJ
admet-2366	374	9	change	change	NOUN
admet-2366	374	10	in	in	ADP
admet-2366	374	11	particle	particle	NOUN
admet-2366	374	12	dimensions	dimension	NOUN
admet-2366	374	13	,	,	PUNCT
admet-2366	374	14	either	either	CCONJ
admet-2366	374	15	due	due	ADP
admet-2366	374	16	to	to	ADP
admet-2366	374	17	enlargement	enlargement	NOUN
admet-2366	374	18	of	of	ADP
admet-2366	374	19	the	the	DET
admet-2366	374	20	outer	outer	ADJ
admet-2366	374	21	layer	layer	NOUN
admet-2366	374	22	or	or	CCONJ
admet-2366	374	23	adaptation	adaptation	NOUN
admet-2366	374	24	in	in	ADP
admet-2366	374	25	their	their	PRON
admet-2366	374	26	morphological	morphological	ADJ
admet-2366	374	27	characteristics	characteristic	NOUN
admet-2366	374	28	.	.	PUNCT
admet-2366	375	1	on	on	ADP
admet-2366	375	2	the	the	DET
admet-2366	375	3	other	other	ADJ
admet-2366	375	4	hand	hand	NOUN
admet-2366	375	5	,	,	PUNCT
admet-2366	375	6	unadorned	unadorned	ADJ
admet-2366	375	7	nanoliposomes	nanoliposome	NOUN
admet-2366	375	8	induced	induce	VERB
admet-2366	375	9	significant	significant	ADJ
admet-2366	375	10	changes	change	NOUN
admet-2366	375	11	in	in	ADP
admet-2366	375	12	size	size	NOUN
admet-2366	375	13	immediately	immediately	ADV
admet-2366	375	14	after	after	ADP
admet-2366	375	15	the	the	DET
admet-2366	375	16	first	first	ADJ
admet-2366	375	17	month	month	NOUN
admet-2366	375	18	.	.	PUNCT
admet-2366	376	1	the	the	DET
admet-2366	376	2	coating	coating	NOUN
admet-2366	376	3	of	of	ADP
admet-2366	376	4	chitosan	chitosan	NOUN
admet-2366	376	5	on	on	ADP
admet-2366	376	6	nanoliposomes	nanoliposome	NOUN
admet-2366	376	7	was	be	AUX
admet-2366	376	8	responsible	responsible	ADJ
admet-2366	376	9	for	for	ADP
admet-2366	376	10	this	this	DET
admet-2366	376	11	assortment	assortment	NOUN
admet-2366	376	12	in	in	ADP
admet-2366	376	13	stability	stability	NOUN
admet-2366	376	14	among	among	ADP
admet-2366	376	15	the	the	DET
admet-2366	376	16	unadorned	unadorned	ADJ
admet-2366	376	17	and	and	CCONJ
admet-2366	376	18	surface	surface	NOUN
admet-2366	376	19	-	-	PUNCT
admet-2366	376	20	adorned	adorn	VERB
admet-2366	376	21	nanoliposomes	nanoliposome	NOUN
admet-2366	376	22	;	;	PUNCT
admet-2366	376	23	its	its	PRON
admet-2366	376	24	multilayer	multilayer	ADJ
admet-2366	376	25	barrier	barrier	NOUN
admet-2366	376	26	can	can	AUX
admet-2366	376	27	obstruct	obstruct	VERB
admet-2366	376	28	the	the	DET
admet-2366	376	29	expansion	expansion	NOUN
admet-2366	376	30	and	and	CCONJ
admet-2366	376	31	discharge	discharge	NOUN
admet-2366	376	32	of	of	ADP
admet-2366	376	33	encapsulated	encapsulate	VERB
admet-2366	376	34	content	content	NOUN
admet-2366	376	35	.	.	PUNCT
admet-2366	377	1	the	the	DET
admet-2366	377	2	stability	stability	NOUN
admet-2366	377	3	of	of	ADP
admet-2366	377	4	plain	plain	ADJ
admet-2366	377	5	nanoliposomes	nanoliposome	NOUN
admet-2366	377	6	has	have	AUX
admet-2366	377	7	increased	increase	VERB
admet-2366	377	8	after	after	ADP
admet-2366	377	9	chitosan	chitosan	NOUN
admet-2366	377	10	coating	coating	NOUN
admet-2366	377	11	.	.	PUNCT
admet-2366	378	1	thus	thus	ADV
admet-2366	378	2	,	,	PUNCT
admet-2366	378	3	by	by	ADP
admet-2366	378	4	using	use	VERB
admet-2366	378	5	different	different	ADJ
admet-2366	378	6	concentrations	concentration	NOUN
admet-2366	378	7	of	of	ADP
admet-2366	378	8	chitosan	chitosan	ADJ
admet-2366	378	9	solution	solution	NOUN
admet-2366	378	10	as	as	ADP
admet-2366	378	11	coating	coating	NOUN
admet-2366	378	12	material	material	NOUN
admet-2366	378	13	,	,	PUNCT
admet-2366	378	14	we	we	PRON
admet-2366	378	15	can	can	AUX
admet-2366	378	16	develop	develop	VERB
admet-2366	378	17	a	a	DET
admet-2366	378	18	suitable	suitable	ADJ
admet-2366	378	19	sustained	sustained	ADJ
admet-2366	378	20	drug	drug	NOUN
admet-2366	378	21	-	-	PUNCT
admet-2366	378	22	release	release	NOUN
admet-2366	378	23	surface	surface	NOUN
admet-2366	378	24	-	-	PUNCT
admet-2366	378	25	adorned	adorn	VERB
admet-2366	378	26	nanoliposomal	nanoliposomal	ADJ
admet-2366	378	27	formulation	formulation	NOUN
admet-2366	378	28	[	[	X
admet-2366	378	29	58,59	58,59	NUM
admet-2366	378	30	]	]	PUNCT
admet-2366	378	31	.	.	PUNCT
admet-2366	379	1	admet	admet	PROPN
admet-2366	379	2	&	&	CCONJ
admet-2366	379	3	dmpk	dmpk	PROPN
admet-2366	379	4	12(4	12(4	PROPN
admet-2366	379	5	)	)	PUNCT
admet-2366	379	6	(	(	PUNCT
admet-2366	379	7	2024	2024	NUM
admet-2366	379	8	)	)	PUNCT
admet-2366	379	9	657	657	NUM
admet-2366	379	10	-	-	SYM
admet-2366	379	11	677	677	NUM
admet-2366	379	12	optimizing	optimizing	NOUN
admet-2366	379	13	gefitinib	gefitinib	NOUN
admet-2366	379	14	nanoliposomes	nanoliposomes	ADV
admet-2366	379	15	doi	doi	ADV
admet-2366	379	16	:	:	PUNCT
admet-2366	379	17	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PRON
admet-2366	379	18	673	673	NUM
admet-2366	379	19	conclusions	conclusion	NOUN
admet-2366	379	20	using	use	VERB
admet-2366	379	21	the	the	DET
admet-2366	379	22	box	box	NOUN
admet-2366	379	23	-	-	PUNCT
admet-2366	379	24	behnken	behnken	VERB
admet-2366	379	25	design	design	NOUN
admet-2366	379	26	,	,	PUNCT
admet-2366	379	27	the	the	DET
admet-2366	379	28	gefitinib	gefitinib	NOUN
admet-2366	379	29	-	-	PUNCT
admet-2366	379	30	loaded	load	VERB
admet-2366	379	31	nanoliposomes	nanoliposome	NOUN
admet-2366	379	32	have	have	AUX
admet-2366	379	33	been	be	AUX
admet-2366	379	34	successfully	successfully	ADV
admet-2366	379	35	formulated	formulate	VERB
admet-2366	379	36	using	use	VERB
admet-2366	379	37	a	a	DET
admet-2366	379	38	reverse	reverse	ADJ
admet-2366	379	39	-	-	PUNCT
admet-2366	379	40	phase	phase	NOUN
admet-2366	379	41	evaporation	evaporation	NOUN
admet-2366	379	42	method	method	NOUN
admet-2366	379	43	.	.	PUNCT
admet-2366	380	1	it	it	PRON
admet-2366	380	2	started	start	VERB
admet-2366	380	3	with	with	ADP
admet-2366	380	4	the	the	DET
admet-2366	380	5	aim	aim	NOUN
admet-2366	380	6	of	of	ADP
admet-2366	380	7	evaluating	evaluate	VERB
admet-2366	380	8	the	the	DET
admet-2366	380	9	effects	effect	NOUN
admet-2366	380	10	of	of	ADP
admet-2366	380	11	three	three	NUM
admet-2366	380	12	independent	independent	ADJ
admet-2366	380	13	variables	variable	NOUN
admet-2366	380	14	on	on	ADP
admet-2366	380	15	the	the	DET
admet-2366	380	16	dependent	dependent	ADJ
admet-2366	380	17	variables	variable	NOUN
admet-2366	380	18	of	of	ADP
admet-2366	380	19	gefitinib	gefitinib	NOUN
admet-2366	380	20	-	-	PUNCT
admet-2366	380	21	loaded	load	VERB
admet-2366	380	22	nanoliposomes	nanoliposome	NOUN
admet-2366	380	23	.	.	PUNCT
admet-2366	381	1	in	in	ADP
admet-2366	381	2	this	this	DET
admet-2366	381	3	regard	regard	NOUN
admet-2366	381	4	,	,	PUNCT
admet-2366	381	5	a	a	DET
admet-2366	381	6	boxbehnken	boxbehnken	VERB
admet-2366	381	7	experimental	experimental	ADJ
admet-2366	381	8	design	design	NOUN
admet-2366	381	9	was	be	AUX
admet-2366	381	10	used	use	VERB
admet-2366	381	11	to	to	PART
admet-2366	381	12	investigate	investigate	VERB
admet-2366	381	13	the	the	DET
admet-2366	381	14	consequences	consequence	NOUN
admet-2366	381	15	of	of	ADP
admet-2366	381	16	independent	independent	ADJ
admet-2366	381	17	variables	variable	NOUN
admet-2366	381	18	and	and	CCONJ
admet-2366	381	19	to	to	PART
admet-2366	381	20	validate	validate	VERB
admet-2366	381	21	the	the	DET
admet-2366	381	22	process	process	NOUN
admet-2366	381	23	circumstances	circumstance	NOUN
admet-2366	381	24	during	during	ADP
admet-2366	381	25	manufacturing	manufacturing	NOUN
admet-2366	381	26	.	.	PUNCT
admet-2366	382	1	then	then	ADV
admet-2366	382	2	,	,	PUNCT
admet-2366	382	3	the	the	DET
admet-2366	382	4	optimum	optimum	ADJ
admet-2366	382	5	batch	batch	NOUN
admet-2366	382	6	was	be	AUX
admet-2366	382	7	coated	coat	VERB
admet-2366	382	8	with	with	ADP
admet-2366	382	9	chitosan	chitosan	NOUN
admet-2366	382	10	.	.	PUNCT
admet-2366	383	1	the	the	DET
admet-2366	383	2	surface	surface	NOUN
admet-2366	383	3	-	-	PUNCT
admet-2366	383	4	adorned	adorn	VERB
admet-2366	383	5	nanoliposomal	nanoliposomal	ADJ
admet-2366	383	6	formulations	formulation	NOUN
admet-2366	383	7	have	have	AUX
admet-2366	383	8	shown	show	VERB
admet-2366	383	9	a	a	DET
admet-2366	383	10	sustained	sustained	ADJ
admet-2366	383	11	release	release	NOUN
admet-2366	383	12	profile	profile	NOUN
admet-2366	383	13	compared	compare	VERB
admet-2366	383	14	to	to	ADP
admet-2366	383	15	the	the	DET
admet-2366	383	16	unadorned	unadorned	ADJ
admet-2366	383	17	optimised	optimise	VERB
admet-2366	383	18	nanoliposomal	nanoliposomal	ADJ
admet-2366	383	19	formulation	formulation	NOUN
admet-2366	383	20	.	.	PUNCT
admet-2366	384	1	reducing	reduce	VERB
admet-2366	384	2	the	the	DET
admet-2366	384	3	associated	associated	ADJ
admet-2366	384	4	side	side	NOUN
admet-2366	384	5	effects	effect	NOUN
admet-2366	384	6	could	could	AUX
admet-2366	384	7	help	help	VERB
admet-2366	384	8	increase	increase	VERB
admet-2366	384	9	patient	patient	ADJ
admet-2366	384	10	compliance	compliance	NOUN
admet-2366	384	11	and	and	CCONJ
admet-2366	384	12	the	the	DET
admet-2366	384	13	therapeutic	therapeutic	ADJ
admet-2366	384	14	index	index	NOUN
admet-2366	384	15	of	of	ADP
admet-2366	384	16	the	the	DET
admet-2366	384	17	drug	drug	NOUN
admet-2366	384	18	.	.	PUNCT
admet-2366	385	1	gefitinib	gefitinib	NOUN
admet-2366	385	2	nanoliposomes	nanoliposomes	AUX
admet-2366	385	3	had	have	AUX
admet-2366	385	4	shown	show	VERB
admet-2366	385	5	less	less	ADJ
admet-2366	385	6	cytotoxicity	cytotoxicity	NOUN
admet-2366	385	7	than	than	ADP
admet-2366	385	8	the	the	DET
admet-2366	385	9	free	free	ADJ
admet-2366	385	10	drug	drug	NOUN
admet-2366	385	11	against	against	ADP
admet-2366	385	12	the	the	DET
admet-2366	385	13	a549	a549	PROPN
admet-2366	385	14	and	and	CCONJ
admet-2366	385	15	h1299	h1299	NUM
admet-2366	385	16	cell	cell	NOUN
admet-2366	385	17	lines	line	NOUN
admet-2366	385	18	.	.	PUNCT
admet-2366	386	1	this	this	PRON
admet-2366	386	2	might	might	AUX
admet-2366	386	3	be	be	AUX
admet-2366	386	4	due	due	ADJ
admet-2366	386	5	to	to	ADP
admet-2366	386	6	the	the	DET
admet-2366	386	7	sluggish	sluggish	ADJ
admet-2366	386	8	discharge	discharge	NOUN
admet-2366	386	9	of	of	ADP
admet-2366	386	10	drugs	drug	NOUN
admet-2366	386	11	from	from	ADP
admet-2366	386	12	nanoliposomes	nanoliposome	NOUN
admet-2366	386	13	.	.	PUNCT
admet-2366	387	1	because	because	SCONJ
admet-2366	387	2	of	of	ADP
admet-2366	387	3	their	their	PRON
admet-2366	387	4	higher	high	ADJ
admet-2366	387	5	zeta	zeta	NOUN
admet-2366	387	6	potential	potential	NOUN
admet-2366	387	7	,	,	PUNCT
admet-2366	387	8	chitosan	chitosan	NOUN
admet-2366	387	9	-	-	PUNCT
admet-2366	387	10	coated	coat	VERB
admet-2366	387	11	nanoliposomes	nanoliposome	NOUN
admet-2366	387	12	had	have	VERB
admet-2366	387	13	a	a	DET
admet-2366	387	14	slightly	slightly	ADV
admet-2366	387	15	higher	high	ADJ
admet-2366	387	16	inhibitory	inhibitory	ADJ
admet-2366	387	17	potential	potential	NOUN
admet-2366	387	18	than	than	ADP
admet-2366	387	19	uncoated	uncoated	ADJ
admet-2366	387	20	formulations	formulation	NOUN
admet-2366	387	21	.	.	PUNCT
admet-2366	388	1	nanoliposomes	nanoliposome	NOUN
admet-2366	388	2	shielded	shield	VERB
admet-2366	388	3	the	the	DET
admet-2366	388	4	encapsulated	encapsulate	VERB
admet-2366	388	5	materials	material	NOUN
admet-2366	388	6	from	from	ADP
admet-2366	388	7	damage	damage	NOUN
admet-2366	388	8	caused	cause	VERB
admet-2366	388	9	by	by	ADP
admet-2366	388	10	the	the	DET
admet-2366	388	11	outside	outside	ADJ
admet-2366	388	12	environment	environment	NOUN
admet-2366	388	13	.	.	PUNCT
admet-2366	389	1	at	at	ADP
admet-2366	389	2	4	4	NUM
admet-2366	389	3	°	°	NOUN
admet-2366	389	4	c	c	NOUN
admet-2366	389	5	,	,	PUNCT
admet-2366	389	6	the	the	DET
admet-2366	389	7	content	content	NOUN
admet-2366	389	8	of	of	ADP
admet-2366	389	9	surface	surface	NOUN
admet-2366	389	10	-	-	PUNCT
admet-2366	389	11	adorned	adorn	VERB
admet-2366	389	12	formulations	formulation	NOUN
admet-2366	389	13	was	be	AUX
admet-2366	389	14	found	find	VERB
admet-2366	389	15	to	to	PART
admet-2366	389	16	be	be	AUX
admet-2366	389	17	more	more	ADV
admet-2366	389	18	durable	durable	ADJ
admet-2366	389	19	than	than	ADP
admet-2366	389	20	uncoated	uncoated	ADJ
admet-2366	389	21	formulations	formulation	NOUN
admet-2366	389	22	.	.	PUNCT
admet-2366	390	1	it	it	PRON
admet-2366	390	2	is	be	AUX
admet-2366	390	3	eminent	eminent	ADJ
admet-2366	390	4	and	and	CCONJ
admet-2366	390	5	acknowledged	acknowledge	VERB
admet-2366	390	6	that	that	SCONJ
admet-2366	390	7	the	the	DET
admet-2366	390	8	biodistribution	biodistribution	NOUN
admet-2366	390	9	of	of	ADP
admet-2366	390	10	coated	coat	VERB
admet-2366	390	11	nanoliposomes	nanoliposome	NOUN
admet-2366	390	12	was	be	AUX
admet-2366	390	13	extensively	extensively	ADV
admet-2366	390	14	exaggerated	exaggerated	ADJ
admet-2366	390	15	by	by	ADP
admet-2366	390	16	their	their	PRON
admet-2366	390	17	surface	surface	NOUN
admet-2366	390	18	properties	property	NOUN
admet-2366	390	19	,	,	PUNCT
admet-2366	390	20	size	size	NOUN
admet-2366	390	21	,	,	PUNCT
admet-2366	390	22	and	and	CCONJ
admet-2366	390	23	stability	stability	NOUN
admet-2366	390	24	.	.	PUNCT
admet-2366	391	1	therefore	therefore	ADV
admet-2366	391	2	,	,	PUNCT
admet-2366	391	3	targeting	target	VERB
admet-2366	391	4	the	the	DET
admet-2366	391	5	entrapped	entrap	VERB
admet-2366	391	6	gefitinib	gefitinib	NOUN
admet-2366	391	7	to	to	ADP
admet-2366	391	8	particular	particular	ADJ
admet-2366	391	9	tissues	tissue	NOUN
admet-2366	391	10	will	will	AUX
admet-2366	391	11	be	be	AUX
admet-2366	391	12	highly	highly	ADV
admet-2366	391	13	favourable	favourable	ADJ
admet-2366	391	14	.	.	PUNCT
admet-2366	392	1	thus	thus	ADV
admet-2366	392	2	,	,	PUNCT
admet-2366	392	3	due	due	ADP
admet-2366	392	4	to	to	ADP
admet-2366	392	5	high	high	ADJ
admet-2366	392	6	permeability	permeability	NOUN
admet-2366	392	7	and	and	CCONJ
admet-2366	392	8	increased	increase	VERB
admet-2366	392	9	drug	drug	NOUN
admet-2366	392	10	accumulation	accumulation	NOUN
admet-2366	392	11	in	in	ADP
admet-2366	392	12	cancer	cancer	NOUN
admet-2366	392	13	cells	cell	NOUN
admet-2366	392	14	,	,	PUNCT
admet-2366	392	15	chitosancoated	chitosancoate	VERB
admet-2366	392	16	nanoliposomes	nanoliposome	NOUN
admet-2366	392	17	can	can	AUX
admet-2366	392	18	be	be	AUX
admet-2366	392	19	suggested	suggest	VERB
admet-2366	392	20	as	as	ADP
admet-2366	392	21	an	an	DET
admet-2366	392	22	appropriate	appropriate	ADJ
admet-2366	392	23	nanocarrier	nanocarrier	NOUN
admet-2366	392	24	to	to	PART
admet-2366	392	25	regulate	regulate	VERB
admet-2366	392	26	the	the	DET
admet-2366	392	27	cancer	cancer	NOUN
admet-2366	392	28	cells	cell	NOUN
admet-2366	392	29	'	'	PART
admet-2366	392	30	expansion	expansion	NOUN
admet-2366	392	31	.	.	PUNCT
admet-2366	393	1	acknowledgements	acknowledgement	NOUN
admet-2366	393	2	:	:	PUNCT
admet-2366	393	3	the	the	DET
admet-2366	393	4	authors	author	NOUN
admet-2366	393	5	show	show	VERB
admet-2366	393	6	gratitude	gratitude	NOUN
admet-2366	393	7	to	to	ADP
admet-2366	393	8	ugc	ugc	PROPN
admet-2366	393	9	,	,	PUNCT
admet-2366	393	10	india	india	PROPN
admet-2366	393	11	for	for	ADP
admet-2366	393	12	granting	grant	VERB
admet-2366	393	13	financial	financial	ADJ
admet-2366	393	14	support	support	NOUN
admet-2366	393	15	.	.	PUNCT
admet-2366	394	1	conflict	conflict	NOUN
admet-2366	394	2	of	of	ADP
admet-2366	394	3	interest	interest	NOUN
admet-2366	394	4	:	:	PUNCT
admet-2366	394	5	the	the	DET
admet-2366	394	6	authors	author	NOUN
admet-2366	394	7	declared	declare	VERB
admet-2366	394	8	that	that	SCONJ
admet-2366	394	9	there	there	PRON
admet-2366	394	10	are	be	VERB
admet-2366	394	11	no	no	DET
admet-2366	394	12	conflicts	conflict	NOUN
admet-2366	394	13	of	of	ADP
admet-2366	394	14	interest	interest	NOUN
admet-2366	394	15	.	.	PUNCT
admet-2366	395	1	funding	funding	NOUN
admet-2366	395	2	:	:	PUNCT
admet-2366	395	3	this	this	DET
admet-2366	395	4	work	work	NOUN
admet-2366	395	5	was	be	AUX
admet-2366	395	6	supported	support	VERB
admet-2366	395	7	by	by	ADP
admet-2366	395	8	the	the	DET
admet-2366	395	9	grant	grant	NOUN
admet-2366	395	10	-	-	PUNCT
admet-2366	395	11	in	in	ADP
admet-2366	395	12	-	-	PUNCT
admet-2366	395	13	aid	aid	NOUN
admet-2366	395	14	to	to	ADP
admet-2366	395	15	department	department	NOUN
admet-2366	395	16	of	of	ADP
admet-2366	395	17	pharmaceutical	pharmaceutical	NOUN
admet-2366	395	18	sciences	sciences	PROPN
admet-2366	395	19	,	,	PUNCT
admet-2366	395	20	maharishi	maharishi	PROPN
admet-2366	395	21	dayanand	dayanand	PROPN
admet-2366	395	22	university	university	PROPN
admet-2366	395	23	,	,	PUNCT
admet-2366	395	24	rohtak	rohtak	PROPN
admet-2366	395	25	,	,	PUNCT
admet-2366	395	26	under	under	ADP
admet-2366	395	27	the	the	DET
admet-2366	395	28	plan	plan	NOUN
admet-2366	395	29	of	of	ADP
admet-2366	395	30	major	major	ADJ
admet-2366	395	31	research	research	NOUN
admet-2366	395	32	project	project	NOUN
admet-2366	395	33	(	(	PUNCT
admet-2366	395	34	f.no.-43	f.no.-43	PROPN
admet-2366	395	35	-	-	X
admet-2366	395	36	485/2014	485/2014	PROPN
admet-2366	395	37	(	(	PUNCT
admet-2366	395	38	sr	sr	PROPN
admet-2366	395	39	)	)	PUNCT
admet-2366	395	40	)	)	PUNCT
admet-2366	395	41	by	by	ADP
admet-2366	395	42	university	university	NOUN
admet-2366	395	43	grants	grant	NOUN
admet-2366	395	44	commission	commission	PROPN
admet-2366	395	45	,	,	PUNCT
admet-2366	395	46	india	india	PROPN
admet-2366	395	47	.	.	PUNCT
admet-2366	396	1	references	reference	NOUN
admet-2366	396	2	[	[	X
admet-2366	396	3	1	1	NUM
admet-2366	396	4	]	]	PUNCT
admet-2366	396	5	a.m.	a.m.	NOUN
admet-2366	397	1	cryer	cryer	PROPN
admet-2366	397	2	,	,	PUNCT
admet-2366	397	3	a.j	a.j	PROPN
admet-2366	397	4	.	.	PROPN
admet-2366	397	5	thorley	thorley	PROPN
admet-2366	397	6	.	.	PUNCT
admet-2366	398	1	nanotechnology	nanotechnology	PROPN
admet-2366	398	2	in	in	ADP
admet-2366	398	3	the	the	DET
admet-2366	398	4	diagnosis	diagnosis	NOUN
admet-2366	398	5	and	and	CCONJ
admet-2366	398	6	treatment	treatment	NOUN
admet-2366	398	7	of	of	ADP
admet-2366	398	8	lung	lung	NOUN
admet-2366	398	9	cancer	cancer	NOUN
admet-2366	398	10	.	.	PUNCT
admet-2366	399	1	pharmacology	pharmacology	NOUN
admet-2366	399	2	&	&	CCONJ
admet-2366	399	3	therapeutics	therapeutic	NOUN
admet-2366	399	4	198	198	NUM
admet-2366	399	5	(	(	PUNCT
admet-2366	399	6	2019	2019	NUM
admet-2366	399	7	)	)	PUNCT
admet-2366	399	8	189	189	NUM
admet-2366	399	9	-	-	SYM
admet-2366	399	10	205	205	NUM
admet-2366	399	11	.	.	PUNCT
admet-2366	400	1	https://doi.org/10.1016/j.pharmthera.2019.02.010	https://doi.org/10.1016/j.pharmthera.2019.02.010	NOUN
admet-2366	400	2	.	.	PUNCT
admet-2366	401	1	[	[	X
admet-2366	401	2	2	2	NUM
admet-2366	401	3	]	]	X
admet-2366	401	4	m.p	m.p	PROPN
admet-2366	401	5	.	.	PROPN
admet-2366	401	6	rivera	rivera	PROPN
admet-2366	401	7	,	,	PUNCT
admet-2366	401	8	a.c	a.c	PROPN
admet-2366	401	9	.	.	PROPN
admet-2366	401	10	mehta	mehta	PROPN
admet-2366	401	11	,	,	PUNCT
admet-2366	401	12	m.m	m.m	PROPN
admet-2366	401	13	.	.	PROPN
admet-2366	401	14	wahidi	wahidi	PROPN
admet-2366	401	15	.	.	PUNCT
admet-2366	402	1	establishing	establish	VERB
admet-2366	402	2	the	the	DET
admet-2366	402	3	diagnosis	diagnosis	NOUN
admet-2366	402	4	of	of	ADP
admet-2366	402	5	lung	lung	NOUN
admet-2366	402	6	cancer	cancer	NOUN
admet-2366	402	7	:	:	PUNCT
admet-2366	402	8	diagnosis	diagnosis	NOUN
admet-2366	402	9	and	and	CCONJ
admet-2366	402	10	management	management	NOUN
admet-2366	402	11	of	of	ADP
admet-2366	402	12	lung	lung	NOUN
admet-2366	402	13	cancer	cancer	NOUN
admet-2366	402	14	.	.	PUNCT
admet-2366	403	1	chest	chest	NOUN
admet-2366	403	2	143	143	NUM
admet-2366	403	3	(	(	PUNCT
admet-2366	403	4	2013	2013	NUM
admet-2366	403	5	)	)	PUNCT
admet-2366	403	6	e142s	e142s	PROPN
admet-2366	403	7	-	-	PUNCT
admet-2366	403	8	e165s	e165s	PROPN
admet-2366	403	9	.	.	PUNCT
admet-2366	404	1	https://doi.org/10.1378/chest.12-2353	https://doi.org/10.1378/chest.12-2353	PROPN
admet-2366	404	2	.	.	PUNCT
admet-2366	405	1	[	[	X
admet-2366	405	2	3	3	NUM
admet-2366	405	3	]	]	X
admet-2366	405	4	b.	b.	PROPN
admet-2366	405	5	hochhegger	hochhegger	PROPN
admet-2366	405	6	,	,	PUNCT
admet-2366	405	7	g.r	g.r	PROPN
admet-2366	405	8	.	.	PROPN
admet-2366	405	9	alves	alves	PROPN
admet-2366	405	10	,	,	PUNCT
admet-2366	405	11	k.l	k.l	PROPN
admet-2366	405	12	.	.	PROPN
admet-2366	405	13	irion	irion	PROPN
admet-2366	405	14	,	,	PUNCT
admet-2366	405	15	c.c	c.c	PROPN
admet-2366	405	16	.	.	PROPN
admet-2366	405	17	fritscher	fritscher	PROPN
admet-2366	405	18	,	,	PUNCT
admet-2366	405	19	l.g	l.g	PROPN
admet-2366	405	20	.	.	PROPN
admet-2366	405	21	fritscher	fritscher	PROPN
admet-2366	405	22	,	,	PUNCT
admet-2366	405	23	n.h	n.h	PROPN
admet-2366	405	24	.	.	PROPN
admet-2366	405	25	concatto	concatto	PROPN
admet-2366	405	26	,	,	PUNCT
admet-2366	405	27	e.	e.	PROPN
admet-2366	405	28	marchiori	marchiori	PROPN
admet-2366	405	29	.	.	PUNCT
admet-2366	406	1	pet	pet	PROPN
admet-2366	406	2	/	/	SYM
admet-2366	406	3	ct	ct	PROPN
admet-2366	406	4	imaging	imaging	NOUN
admet-2366	406	5	in	in	ADP
admet-2366	406	6	lung	lung	NOUN
admet-2366	406	7	cancer	cancer	NOUN
admet-2366	406	8	:	:	PUNCT
admet-2366	406	9	indications	indication	NOUN
admet-2366	406	10	and	and	CCONJ
admet-2366	406	11	findings	finding	NOUN
admet-2366	406	12	.	.	PUNCT
admet-2366	407	1	jornal	jornal	ADJ
admet-2366	407	2	brasileiro	brasileiro	PROPN
admet-2366	407	3	de	de	PROPN
admet-2366	407	4	pneumologia	pneumologia	PROPN
admet-2366	407	5	41	41	NUM
admet-2366	407	6	(	(	PUNCT
admet-2366	407	7	2015	2015	NUM
admet-2366	407	8	)	)	PUNCT
admet-2366	407	9	264	264	NUM
admet-2366	407	10	-	-	SYM
admet-2366	407	11	274	274	NUM
admet-2366	407	12	.	.	PUNCT
admet-2366	408	1	https://doi.org/10.1590/s1806-37132015000004479	https://doi.org/10.1590/s1806-37132015000004479	PROPN
admet-2366	408	2	.	.	PUNCT
admet-2366	409	1	[	[	X
admet-2366	409	2	4	4	X
admet-2366	409	3	]	]	X
admet-2366	409	4	e.	e.	PROPN
admet-2366	409	5	carrasco	carrasco	PROPN
admet-2366	409	6	-	-	PUNCT
admet-2366	409	7	esteban	esteban	PROPN
admet-2366	409	8	,	,	PUNCT
admet-2366	409	9	j.a	j.a	PROPN
admet-2366	409	10	.	.	PROPN
admet-2366	409	11	dominguez	dominguez	PROPN
admet-2366	409	12	-	-	PUNCT
admet-2366	409	13	rullan	rullan	NOUN
admet-2366	409	14	,	,	PUNCT
admet-2366	409	15	p.	p.	PROPN
admet-2366	409	16	barrionuevo	barrionuevo	PROPN
admet-2366	409	17	-	-	PUNCT
admet-2366	409	18	castillo	castillo	PROPN
admet-2366	409	19	,	,	PUNCT
admet-2366	409	20	l.	l.	PROPN
admet-2366	409	21	pelari	pelari	PROPN
admet-2366	409	22	-	-	PUNCT
admet-2366	409	23	mici	mici	ADJ
admet-2366	409	24	,	,	PUNCT
admet-2366	409	25	o.	o.	PROPN
admet-2366	409	26	leaman	leaman	NOUN
admet-2366	409	27	,	,	PUNCT
admet-2366	409	28	s.	s.	PROPN
admet-2366	409	29	sastre	sastre	NOUN
admet-2366	409	30	-	-	PUNCT
admet-2366	409	31	gallego	gallego	NOUN
admet-2366	409	32	,	,	PUNCT
admet-2366	409	33	f.	f.	PROPN
admet-2366	409	34	lópez	lópez	PROPN
admet-2366	409	35	-	-	PUNCT
admet-2366	409	36	campos	campos	PROPN
admet-2366	409	37	.	.	PUNCT
admet-2366	410	1	current	current	ADJ
admet-2366	410	2	role	role	NOUN
admet-2366	410	3	of	of	ADP
admet-2366	410	4	nanoparticles	nanoparticle	NOUN
admet-2366	410	5	in	in	ADP
admet-2366	410	6	the	the	DET
admet-2366	410	7	treatment	treatment	NOUN
admet-2366	410	8	of	of	ADP
admet-2366	410	9	lung	lung	NOUN
admet-2366	410	10	cancer	cancer	NOUN
admet-2366	410	11	.	.	PUNCT
admet-2366	411	1	journal	journal	NOUN
admet-2366	411	2	of	of	ADP
admet-2366	411	3	clinical	clinical	ADJ
admet-2366	411	4	and	and	CCONJ
admet-2366	411	5	translational	translational	ADJ
admet-2366	411	6	research	research	NOUN
admet-2366	411	7	7	7	NUM
admet-2366	411	8	(	(	PUNCT
admet-2366	411	9	2021	2021	NUM
admet-2366	411	10	)	)	PUNCT
admet-2366	411	11	140	140	NUM
admet-2366	411	12	-	-	SYM
admet-2366	411	13	155	155	NUM
admet-2366	411	14	.	.	PUNCT
admet-2366	412	1	https://doi.org/10.18053/jctres.07.202102.005	https://doi.org/10.18053/jctres.07.202102.005	NOUN
admet-2366	412	2	.	.	PUNCT
admet-2366	413	1	[	[	X
admet-2366	413	2	5	5	X
admet-2366	413	3	]	]	X
admet-2366	413	4	y.e	y.e	PROPN
admet-2366	413	5	.	.	PROPN
admet-2366	413	6	miller	miller	PROPN
admet-2366	413	7	.	.	PUNCT
admet-2366	414	1	pathogenesis	pathogenesis	NOUN
admet-2366	414	2	of	of	ADP
admet-2366	414	3	lung	lung	NOUN
admet-2366	414	4	cancer	cancer	NOUN
admet-2366	414	5	.	.	PUNCT
admet-2366	415	1	american	american	ADJ
admet-2366	415	2	journal	journal	PROPN
admet-2366	415	3	of	of	ADP
admet-2366	415	4	respiratory	respiratory	ADJ
admet-2366	415	5	cell	cell	NOUN
admet-2366	415	6	and	and	CCONJ
admet-2366	415	7	molecular	molecular	ADJ
admet-2366	415	8	biology	biology	NOUN
admet-2366	415	9	33	33	NUM
admet-2366	415	10	(	(	PUNCT
admet-2366	415	11	2005	2005	NUM
admet-2366	415	12	)	)	PUNCT
admet-2366	415	13	216	216	NUM
admet-2366	415	14	-	-	SYM
admet-2366	415	15	223	223	NUM
admet-2366	415	16	.	.	PUNCT
admet-2366	416	1	https://doi.org/10.1165/rcmb.2005-0158oe	https://doi.org/10.1165/rcmb.2005-0158oe	PROPN
admet-2366	416	2	.	.	PUNCT
admet-2366	417	1	[	[	X
admet-2366	417	2	6	6	NUM
admet-2366	417	3	]	]	X
admet-2366	417	4	a.v	a.v	PROPN
admet-2366	417	5	.	.	PROPN
admet-2366	417	6	tonder	tonder	PROPN
admet-2366	417	7	,	,	PUNCT
admet-2366	417	8	a.m.	a.m.	PROPN
admet-2366	417	9	joubert	joubert	PROPN
admet-2366	417	10	,	,	PUNCT
admet-2366	417	11	a.d	a.d	PROPN
admet-2366	417	12	.	.	PROPN
admet-2366	417	13	cromarty	cromarty	PROPN
admet-2366	417	14	.	.	PUNCT
admet-2366	418	1	limitations	limitation	NOUN
admet-2366	418	2	of	of	ADP
admet-2366	418	3	the	the	DET
admet-2366	418	4	3-(4,5	3-(4,5	PROPN
admet-2366	418	5	-	-	PUNCT
admet-2366	418	6	dimethylthiazol-2	dimethylthiazol-2	NUM
admet-2366	418	7	-	-	PUNCT
admet-2366	418	8	yl)-2,5diphenyl-2h	yl)-2,5diphenyl-2h	NOUN
admet-2366	418	9	-	-	PUNCT
admet-2366	418	10	tetrazolium	tetrazolium	NOUN
admet-2366	418	11	bromide	bromide	NOUN
admet-2366	418	12	(	(	PUNCT
admet-2366	418	13	mtt	mtt	NOUN
admet-2366	418	14	)	)	PUNCT
admet-2366	418	15	assay	assay	VERB
admet-2366	418	16	when	when	SCONJ
admet-2366	418	17	compared	compare	VERB
admet-2366	418	18	to	to	ADP
admet-2366	418	19	three	three	NUM
admet-2366	418	20	commonly	commonly	ADV
admet-2366	418	21	used	use	VERB
admet-2366	418	22	cell	cell	NOUN
admet-2366	418	23	enumeration	enumeration	NOUN
admet-2366	418	24	assays	assay	NOUN
admet-2366	418	25	.	.	PUNCT
admet-2366	419	1	bmc	bmc	ADJ
admet-2366	419	2	research	research	NOUN
admet-2366	419	3	notes	note	VERB
admet-2366	419	4	8	8	NUM
admet-2366	419	5	(	(	PUNCT
admet-2366	419	6	2015	2015	NUM
admet-2366	419	7	)	)	PUNCT
admet-2366	419	8	47	47	NUM
admet-2366	419	9	.	.	PUNCT
admet-2366	420	1	https://doi.org/10.1186/s13104-015-1000-8	https://doi.org/10.1186/s13104-015-1000-8	NUM
admet-2366	420	2	.	.	PUNCT
admet-2366	421	1	[	[	X
admet-2366	421	2	7	7	X
admet-2366	421	3	]	]	X
admet-2366	421	4	m.	m.	NOUN
admet-2366	421	5	ginouves	ginouves	PROPN
admet-2366	421	6	,	,	PUNCT
admet-2366	421	7	b.	b.	PROPN
admet-2366	421	8	carme	carme	PROPN
admet-2366	421	9	,	,	PUNCT
admet-2366	421	10	p.	p.	PROPN
admet-2366	421	11	couppie	couppie	PROPN
admet-2366	421	12	,	,	PUNCT
admet-2366	421	13	g.	g.	PROPN
admet-2366	421	14	prevot	prevot	PROPN
admet-2366	421	15	.	.	PUNCT
admet-2366	422	1	comparison	comparison	NOUN
admet-2366	422	2	of	of	ADP
admet-2366	422	3	tetrazolium	tetrazolium	NOUN
admet-2366	422	4	salt	salt	NOUN
admet-2366	422	5	assays	assay	NOUN
admet-2366	422	6	for	for	ADP
admet-2366	422	7	evaluation	evaluation	NOUN
admet-2366	422	8	of	of	ADP
admet-2366	422	9	drug	drug	NOUN
admet-2366	422	10	activity	activity	NOUN
admet-2366	422	11	against	against	ADP
admet-2366	422	12	leishmania	leishmania	NOUN
admet-2366	422	13	spp	spp	PROPN
admet-2366	422	14	.	.	PROPN
admet-2366	422	15	journal	journal	PROPN
admet-2366	422	16	of	of	ADP
admet-2366	422	17	clinical	clinical	ADJ
admet-2366	422	18	microbiology	microbiology	NOUN
admet-2366	422	19	52	52	NUM
admet-2366	422	20	(	(	PUNCT
admet-2366	422	21	2014	2014	NUM
admet-2366	422	22	)	)	PUNCT
admet-2366	422	23	2131	2131	NUM
admet-2366	422	24	-	-	SYM
admet-2366	422	25	2138	2138	NUM
admet-2366	422	26	.	.	PUNCT
admet-2366	423	1	https://doi.org/10.1128/jcm.00201-14	https://doi.org/10.1128/jcm.00201-14	PROPN
admet-2366	423	2	.	.	PUNCT
admet-2366	424	1	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PROPN
admet-2366	424	2	https://doi.org/10.1016/j.pharmthera.2019.02.010	https://doi.org/10.1016/j.pharmthera.2019.02.010	NOUN
admet-2366	424	3	https://doi.org/10.1378/chest.12-2353	https://doi.org/10.1378/chest.12-2353	PROPN
admet-2366	424	4	https://doi.org/10.1590/s1806-37132015000004479	https://doi.org/10.1590/s1806-37132015000004479	PROPN
admet-2366	424	5	https://doi.org/10.18053/jctres.07.202102.005	https://doi.org/10.18053/jctres.07.202102.005	PROPN
admet-2366	424	6	https://doi.org/10.1165/rcmb.2005-0158oe	https://doi.org/10.1165/rcmb.2005-0158oe	VERB
admet-2366	424	7	https://doi.org/10.1186/s13104-015-1000-8	https://doi.org/10.1186/s13104-015-1000-8	NUM
admet-2366	425	1	https://doi.org/10.1128/jcm.00201-14	https://doi.org/10.1128/jcm.00201-14	PROPN
admet-2366	425	2	s.	s.	PROPN
admet-2366	425	3	rohilla	rohilla	PROPN
admet-2366	425	4	et	et	PROPN
admet-2366	425	5	al	al	PROPN
admet-2366	425	6	.	.	PROPN
admet-2366	425	7	admet	admet	PROPN
admet-2366	425	8	&	&	CCONJ
admet-2366	425	9	dmpk	dmpk	PROPN
admet-2366	425	10	12(4	12(4	PROPN
admet-2366	425	11	)	)	PUNCT
admet-2366	425	12	(	(	PUNCT
admet-2366	425	13	2024	2024	NUM
admet-2366	425	14	)	)	PUNCT
admet-2366	425	15	657	657	NUM
admet-2366	425	16	-	-	SYM
admet-2366	425	17	677	677	NUM
admet-2366	425	18	674	674	NUM
admet-2366	425	19	[	[	NOUN
admet-2366	425	20	8	8	NUM
admet-2366	425	21	]	]	X
admet-2366	425	22	y.	y.	PROPN
admet-2366	425	23	shi	shi	PROPN
admet-2366	425	24	,	,	PUNCT
admet-2366	425	25	c.	c.	PROPN
admet-2366	425	26	su	su	PROPN
admet-2366	425	27	,	,	PUNCT
admet-2366	425	28	w.	w.	PROPN
admet-2366	425	29	cui	cui	PROPN
admet-2366	425	30	,	,	PUNCT
admet-2366	425	31	h.	h.	PROPN
admet-2366	425	32	li	li	PROPN
admet-2366	425	33	,	,	PUNCT
admet-2366	425	34	l.	l.	PROPN
admet-2366	425	35	liu	liu	PROPN
admet-2366	425	36	,	,	PUNCT
admet-2366	425	37	b.	b.	PROPN
admet-2366	425	38	feng	feng	PROPN
admet-2366	425	39	,	,	PUNCT
admet-2366	425	40	m.	m.	PROPN
admet-2366	425	41	liu	liu	PROPN
admet-2366	425	42	,	,	PUNCT
admet-2366	425	43	r.	r.	PROPN
admet-2366	425	44	su	su	PROPN
admet-2366	425	45	,	,	PUNCT
admet-2366	425	46	l.	l.	PROPN
admet-2366	425	47	zhao	zhao	PROPN
admet-2366	425	48	.	.	PUNCT
admet-2366	426	1	gefitinib	gefitinib	NOUN
admet-2366	426	2	loaded	load	VERB
admet-2366	426	3	folate	folate	NOUN
admet-2366	426	4	decorated	decorate	VERB
admet-2366	426	5	bovine	bovine	NOUN
admet-2366	426	6	serum	serum	NOUN
admet-2366	426	7	albumin	albumin	PROPN
admet-2366	426	8	conjugated	conjugate	VERB
admet-2366	426	9	carboxymethyl	carboxymethyl	NOUN
admet-2366	426	10	-	-	PUNCT
admet-2366	426	11	beta	beta	NOUN
admet-2366	426	12	-	-	PUNCT
admet-2366	426	13	cyclodextrin	cyclodextrin	NOUN
admet-2366	426	14	nanoparticles	nanoparticle	NOUN
admet-2366	426	15	enhance	enhance	VERB
admet-2366	426	16	drug	drug	NOUN
admet-2366	426	17	delivery	delivery	NOUN
admet-2366	426	18	and	and	CCONJ
admet-2366	426	19	attenuate	attenuate	VERB
admet-2366	426	20	autophagy	autophagy	ADV
admet-2366	426	21	in	in	ADP
admet-2366	426	22	folate	folate	NOUN
admet-2366	426	23	receptor	receptor	NOUN
admet-2366	426	24	-	-	PUNCT
admet-2366	426	25	positive	positive	ADJ
admet-2366	426	26	cancer	cancer	NOUN
admet-2366	426	27	cells	cell	NOUN
admet-2366	426	28	.	.	PUNCT
admet-2366	427	1	journal	journal	NOUN
admet-2366	427	2	of	of	ADP
admet-2366	427	3	nanobiotechnology	nanobiotechnology	NOUN
admet-2366	427	4	12	12	NUM
admet-2366	427	5	(	(	PUNCT
admet-2366	427	6	2014	2014	NUM
admet-2366	427	7	)	)	PUNCT
admet-2366	427	8	43	43	NUM
admet-2366	427	9	.	.	PUNCT
admet-2366	428	1	https://doi.org/10.1186/s12951-014-0043-7	https://doi.org/10.1186/s12951-014-0043-7	PROPN
admet-2366	428	2	.	.	PUNCT
admet-2366	429	1	[	[	X
admet-2366	429	2	9	9	NUM
admet-2366	429	3	]	]	PUNCT
admet-2366	429	4	m.	m.	NOUN
admet-2366	429	5	chougule	chougule	NOUN
admet-2366	429	6	,	,	PUNCT
admet-2366	429	7	b.	b.	PROPN
admet-2366	429	8	padhi	padhi	PROPN
admet-2366	429	9	,	,	PUNCT
admet-2366	429	10	a.	a.	NOUN
admet-2366	429	11	misra	misra	PROPN
admet-2366	429	12	.	.	PUNCT
admet-2366	430	1	nano	nano	NOUN
admet-2366	430	2	-	-	PUNCT
admet-2366	430	3	liposomal	liposomal	ADJ
admet-2366	430	4	dry	dry	ADJ
admet-2366	430	5	powder	powder	NOUN
admet-2366	430	6	inhaler	inhaler	NOUN
admet-2366	430	7	of	of	ADP
admet-2366	430	8	tacrolimus	tacrolimus	NOUN
admet-2366	430	9	:	:	PUNCT
admet-2366	430	10	preparation	preparation	NOUN
admet-2366	430	11	,	,	PUNCT
admet-2366	430	12	characterization	characterization	NOUN
admet-2366	430	13	,	,	PUNCT
admet-2366	430	14	and	and	CCONJ
admet-2366	430	15	pulmonary	pulmonary	ADJ
admet-2366	430	16	pharmacokinetics	pharmacokinetic	NOUN
admet-2366	430	17	.	.	PUNCT
admet-2366	431	1	international	international	ADJ
admet-2366	431	2	journal	journal	NOUN
admet-2366	431	3	of	of	ADP
admet-2366	431	4	nanomedicine	nanomedicine	ADJ
admet-2366	431	5	2	2	NUM
admet-2366	431	6	(	(	PUNCT
admet-2366	431	7	2007	2007	NUM
admet-2366	431	8	)	)	PUNCT
admet-2366	431	9	675	675	NUM
admet-2366	431	10	-	-	SYM
admet-2366	431	11	688	688	NUM
admet-2366	431	12	.	.	PUNCT
admet-2366	432	1	https://doi.org/10.2147/ijn.s2.4.675	https://doi.org/10.2147/ijn.s2.4.675	NOUN
admet-2366	432	2	.	.	PUNCT
admet-2366	433	1	[	[	X
admet-2366	433	2	10	10	NUM
admet-2366	433	3	]	]	X
admet-2366	433	4	c.	c.	PROPN
admet-2366	433	5	zappa	zappa	PROPN
admet-2366	433	6	,	,	PUNCT
admet-2366	433	7	s.a	s.a	PROPN
admet-2366	433	8	.	.	PROPN
admet-2366	433	9	mousa	mousa	PROPN
admet-2366	433	10	.	.	PUNCT
admet-2366	434	1	non	non	ADJ
admet-2366	434	2	-	-	ADJ
admet-2366	434	3	small	small	ADJ
admet-2366	434	4	cell	cell	NOUN
admet-2366	434	5	lung	lung	NOUN
admet-2366	434	6	cancer	cancer	NOUN
admet-2366	434	7	:	:	PUNCT
admet-2366	434	8	current	current	ADJ
admet-2366	434	9	treatment	treatment	NOUN
admet-2366	434	10	and	and	CCONJ
admet-2366	434	11	future	future	ADJ
admet-2366	434	12	advances	advance	NOUN
admet-2366	434	13	.	.	PUNCT
admet-2366	435	1	translational	translational	ADJ
admet-2366	435	2	lung	lung	NOUN
admet-2366	435	3	cancer	cancer	NOUN
admet-2366	435	4	research	research	NOUN
admet-2366	435	5	5	5	NUM
admet-2366	435	6	(	(	PUNCT
admet-2366	435	7	2016	2016	NUM
admet-2366	435	8	)	)	PUNCT
admet-2366	435	9	288	288	NUM
admet-2366	435	10	-	-	SYM
admet-2366	435	11	300	300	NUM
admet-2366	435	12	.	.	PUNCT
admet-2366	436	1	https://doi.org/10.21037/tlcr.2016.06.07	https://doi.org/10.21037/tlcr.2016.06.07	X
admet-2366	436	2	.	.	PUNCT
admet-2366	437	1	[	[	X
admet-2366	437	2	11	11	NUM
admet-2366	437	3	]	]	PUNCT
admet-2366	437	4	m.	m.	NOUN
admet-2366	437	5	tiseo	tiseo	NOUN
admet-2366	437	6	,	,	PUNCT
admet-2366	437	7	m.	m.	NOUN
admet-2366	437	8	bartolotti	bartolotti	PROPN
admet-2366	437	9	,	,	PUNCT
admet-2366	437	10	f.	f.	PROPN
admet-2366	437	11	gelsomino	gelsomino	PROPN
admet-2366	437	12	,	,	PUNCT
admet-2366	437	13	p.	p.	NOUN
admet-2366	437	14	bordi	bordi	NOUN
admet-2366	437	15	.	.	PUNCT
admet-2366	438	1	emerging	emerge	VERB
admet-2366	438	2	role	role	NOUN
admet-2366	438	3	of	of	ADP
admet-2366	438	4	gefitinib	gefitinib	NOUN
admet-2366	438	5	in	in	ADP
admet-2366	438	6	the	the	DET
admet-2366	438	7	treatment	treatment	NOUN
admet-2366	438	8	of	of	ADP
admet-2366	438	9	nonsmall	nonsmall	ADJ
admet-2366	438	10	-	-	PUNCT
admet-2366	438	11	cell	cell	NOUN
admet-2366	438	12	lung	lung	NOUN
admet-2366	438	13	cancer	cancer	NOUN
admet-2366	438	14	(	(	PUNCT
admet-2366	438	15	nsclc	nsclc	NOUN
admet-2366	438	16	)	)	PUNCT
admet-2366	438	17	.	.	PUNCT
admet-2366	439	1	drug	drug	NOUN
admet-2366	439	2	design	design	NOUN
admet-2366	439	3	,	,	PUNCT
admet-2366	439	4	development	development	NOUN
admet-2366	439	5	and	and	CCONJ
admet-2366	439	6	therapy	therapy	NOUN
admet-2366	439	7	4	4	NUM
admet-2366	439	8	(	(	PUNCT
admet-2366	439	9	2010	2010	NUM
admet-2366	439	10	)	)	PUNCT
admet-2366	439	11	81	81	NUM
admet-2366	439	12	-	-	SYM
admet-2366	439	13	98	98	NUM
admet-2366	439	14	.	.	PUNCT
admet-2366	440	1	https://doi.org/10.2147/dddt.s6594	https://doi.org/10.2147/dddt.s6594	NOUN
admet-2366	440	2	.	.	PUNCT
admet-2366	441	1	[	[	X
admet-2366	441	2	12	12	NUM
admet-2366	441	3	]	]	X
admet-2366	441	4	c.	c.	NOUN
admet-2366	441	5	godugu	godugu	NOUN
admet-2366	441	6	,	,	PUNCT
admet-2366	441	7	r.	r.	PROPN
admet-2366	441	8	doddapaneni	doddapaneni	PROPN
admet-2366	441	9	,	,	PUNCT
admet-2366	441	10	a.r	a.r	PROPN
admet-2366	441	11	.	.	PROPN
admet-2366	441	12	patel	patel	PROPN
admet-2366	441	13	,	,	PUNCT
admet-2366	441	14	r.	r.	PROPN
admet-2366	441	15	singh	singh	PROPN
admet-2366	441	16	,	,	PUNCT
admet-2366	441	17	r.	r.	PROPN
admet-2366	441	18	mercer	mercer	PROPN
admet-2366	441	19	,	,	PUNCT
admet-2366	441	20	m.	m.	NOUN
admet-2366	441	21	singh	singh	PROPN
admet-2366	441	22	.	.	PUNCT
admet-2366	442	1	novel	novel	ADJ
admet-2366	442	2	gefitinib	gefitinib	NOUN
admet-2366	442	3	formulation	formulation	NOUN
admet-2366	442	4	with	with	ADP
admet-2366	442	5	improved	improved	ADJ
admet-2366	442	6	oral	oral	ADJ
admet-2366	442	7	bioavailability	bioavailability	NOUN
admet-2366	442	8	in	in	ADP
admet-2366	442	9	treatment	treatment	NOUN
admet-2366	442	10	of	of	ADP
admet-2366	442	11	a431	a431	PROPN
admet-2366	442	12	skin	skin	NOUN
admet-2366	442	13	carcinoma	carcinoma	NOUN
admet-2366	442	14	.	.	PUNCT
admet-2366	443	1	pharmaceutical	pharmaceutical	ADJ
admet-2366	443	2	research	research	NOUN
admet-2366	443	3	33	33	NUM
admet-2366	443	4	(	(	PUNCT
admet-2366	443	5	2016	2016	NUM
admet-2366	443	6	)	)	PUNCT
admet-2366	443	7	137	137	NUM
admet-2366	443	8	-	-	SYM
admet-2366	443	9	154	154	NUM
admet-2366	443	10	.	.	PUNCT
admet-2366	444	1	https://doi.org/10.1007/s11095-015-1771-6	https://doi.org/10.1007/s11095-015-1771-6	NUM
admet-2366	444	2	.	.	PUNCT
admet-2366	445	1	[	[	X
admet-2366	445	2	13	13	NUM
admet-2366	445	3	]	]	X
admet-2366	445	4	i.n	i.n	PROPN
admet-2366	445	5	.	.	PROPN
admet-2366	445	6	maruyama	maruyama	PROPN
admet-2366	445	7	.	.	PUNCT
admet-2366	446	1	mechanisms	mechanism	NOUN
admet-2366	446	2	of	of	ADP
admet-2366	446	3	activation	activation	NOUN
admet-2366	446	4	of	of	ADP
admet-2366	446	5	receptor	receptor	NOUN
admet-2366	446	6	tyrosine	tyrosine	NOUN
admet-2366	446	7	kinases	kinase	NOUN
admet-2366	446	8	:	:	PUNCT
admet-2366	446	9	monomers	monomer	NOUN
admet-2366	446	10	or	or	CCONJ
admet-2366	446	11	dimers	dimer	NOUN
admet-2366	446	12	.	.	PUNCT
admet-2366	447	1	cells	cell	NOUN
admet-2366	447	2	3	3	NUM
admet-2366	447	3	(	(	PUNCT
admet-2366	447	4	2014	2014	NUM
admet-2366	447	5	)	)	PUNCT
admet-2366	447	6	304	304	NUM
admet-2366	447	7	-	-	SYM
admet-2366	447	8	330	330	NUM
admet-2366	447	9	.	.	PUNCT
admet-2366	448	1	https://doi.org/10.3390/cells3020304	https://doi.org/10.3390/cells3020304	PROPN
admet-2366	448	2	.	.	PUNCT
admet-2366	449	1	[	[	X
admet-2366	449	2	14	14	NUM
admet-2366	449	3	]	]	X
admet-2366	449	4	p.p	p.p	PROPN
admet-2366	449	5	.	.	PROPN
admet-2366	449	6	deshpande	deshpande	PROPN
admet-2366	449	7	,	,	PUNCT
admet-2366	449	8	s.	s.	PROPN
admet-2366	449	9	biswas	biswas	PROPN
admet-2366	449	10	,	,	PUNCT
admet-2366	449	11	v.p	v.p	PROPN
admet-2366	449	12	.	.	PROPN
admet-2366	449	13	torchilin	torchilin	PROPN
admet-2366	449	14	.	.	PUNCT
admet-2366	450	1	current	current	ADJ
admet-2366	450	2	trends	trend	NOUN
admet-2366	450	3	in	in	ADP
admet-2366	450	4	the	the	DET
admet-2366	450	5	use	use	NOUN
admet-2366	450	6	of	of	ADP
admet-2366	450	7	liposomes	liposome	NOUN
admet-2366	450	8	for	for	ADP
admet-2366	450	9	tumor	tumor	NOUN
admet-2366	450	10	targeting	target	VERB
admet-2366	450	11	.	.	PUNCT
admet-2366	451	1	nanomedicine	nanomedicine	NOUN
admet-2366	451	2	8	8	NUM
admet-2366	451	3	(	(	PUNCT
admet-2366	451	4	2013	2013	NUM
admet-2366	451	5	)	)	PUNCT
admet-2366	451	6	1509	1509	NUM
admet-2366	451	7	-	-	SYM
admet-2366	451	8	1528	1528	NUM
admet-2366	451	9	.	.	PUNCT
admet-2366	452	1	https://doi.org/10.2217/nnm.13.118	https://doi.org/10.2217/nnm.13.118	X
admet-2366	452	2	.	.	PUNCT
admet-2366	453	1	[	[	X
admet-2366	453	2	15	15	NUM
admet-2366	453	3	]	]	X
admet-2366	453	4	g.	g.	PROPN
admet-2366	453	5	bozzuto	bozzuto	PROPN
admet-2366	453	6	,	,	PUNCT
admet-2366	453	7	a.	a.	PROPN
admet-2366	453	8	molinari	molinari	PROPN
admet-2366	453	9	.	.	PUNCT
admet-2366	454	1	liposomes	liposome	NOUN
admet-2366	454	2	as	as	ADP
admet-2366	454	3	nanomedical	nanomedical	ADJ
admet-2366	454	4	devices	device	NOUN
admet-2366	454	5	.	.	PUNCT
admet-2366	455	1	international	international	ADJ
admet-2366	455	2	journal	journal	PROPN
admet-2366	455	3	of	of	ADP
admet-2366	455	4	nanomedicine	nanomedicine	NOUN
admet-2366	455	5	10	10	NUM
admet-2366	455	6	(	(	PUNCT
admet-2366	455	7	2015	2015	NUM
admet-2366	455	8	)	)	PUNCT
admet-2366	455	9	975	975	NUM
admet-2366	455	10	-	-	SYM
admet-2366	455	11	999	999	NUM
admet-2366	455	12	.	.	PUNCT
admet-2366	455	13	https://doi.org/10.2147/ijn.s68861	https://doi.org/10.2147/ijn.s68861	NUM
admet-2366	455	14	.	.	PUNCT
admet-2366	456	1	[	[	X
admet-2366	456	2	16	16	NUM
admet-2366	456	3	]	]	X
admet-2366	456	4	j.	j.	PROPN
admet-2366	456	5	ni	ni	PROPN
admet-2366	456	6	,	,	PUNCT
admet-2366	456	7	l.	l.	PROPN
admet-2366	456	8	zhang	zhang	PROPN
admet-2366	456	9	.	.	PUNCT
admet-2366	456	10	evaluation	evaluation	NOUN
admet-2366	456	11	of	of	ADP
admet-2366	456	12	three	three	NUM
admet-2366	456	13	small	small	ADJ
admet-2366	456	14	molecular	molecular	ADJ
admet-2366	456	15	drugs	drug	NOUN
admet-2366	456	16	for	for	ADP
admet-2366	456	17	targeted	target	VERB
admet-2366	456	18	therapy	therapy	NOUN
admet-2366	456	19	to	to	PART
admet-2366	456	20	treat	treat	VERB
admet-2366	456	21	nonsmall	nonsmall	NOUN
admet-2366	456	22	cell	cell	NOUN
admet-2366	456	23	lung	lung	NOUN
admet-2366	456	24	cancer	cancer	NOUN
admet-2366	456	25	.	.	PUNCT
admet-2366	457	1	chinese	chinese	ADJ
admet-2366	457	2	medical	medical	ADJ
admet-2366	457	3	journal	journal	PROPN
admet-2366	457	4	129	129	NUM
admet-2366	457	5	(	(	PUNCT
admet-2366	457	6	2016	2016	NUM
admet-2366	457	7	)	)	PUNCT
admet-2366	457	8	332	332	NUM
admet-2366	457	9	-	-	SYM
admet-2366	457	10	340	340	NUM
admet-2366	457	11	.	.	PUNCT
admet-2366	458	1	https://doi.org/10.4103/03666999.174484	https://doi.org/10.4103/03666999.174484	NOUN
admet-2366	458	2	.	.	PUNCT
admet-2366	459	1	[	[	X
admet-2366	459	2	17	17	NUM
admet-2366	459	3	]	]	X
admet-2366	459	4	j.h	j.h	PROPN
admet-2366	459	5	.	.	PROPN
admet-2366	459	6	nam	nam	PROPN
admet-2366	459	7	,	,	PUNCT
admet-2366	459	8	s.y	s.y	PROPN
admet-2366	459	9	.	.	PROPN
admet-2366	459	10	kim	kim	PROPN
admet-2366	459	11	,	,	PUNCT
admet-2366	459	12	h.	h.	PROPN
admet-2366	459	13	seong	seong	PROPN
admet-2366	459	14	.	.	PUNCT
admet-2366	460	1	investigation	investigation	NOUN
admet-2366	460	2	on	on	ADP
admet-2366	460	3	physicochemical	physicochemical	ADJ
admet-2366	460	4	characteristics	characteristic	NOUN
admet-2366	460	5	of	of	ADP
admet-2366	460	6	a	a	DET
admet-2366	460	7	nanoliposomebased	nanoliposomebased	ADJ
admet-2366	460	8	system	system	NOUN
admet-2366	460	9	for	for	ADP
admet-2366	460	10	dual	dual	ADJ
admet-2366	460	11	drug	drug	NOUN
admet-2366	460	12	delivery	delivery	NOUN
admet-2366	460	13	.	.	PUNCT
admet-2366	461	1	nanoscale	nanoscale	NOUN
admet-2366	461	2	research	research	NOUN
admet-2366	461	3	letters	letter	NOUN
admet-2366	461	4	13	13	NUM
admet-2366	461	5	(	(	PUNCT
admet-2366	461	6	2018	2018	NUM
admet-2366	461	7	)	)	PUNCT
admet-2366	461	8	101	101	NUM
admet-2366	461	9	.	.	PUNCT
admet-2366	462	1	https://doi.org/10.1186/s11671-018-2519-0	https://doi.org/10.1186/s11671-018-2519-0	NUM
admet-2366	462	2	.	.	PUNCT
admet-2366	463	1	[	[	X
admet-2366	463	2	18	18	NUM
admet-2366	463	3	]	]	X
admet-2366	463	4	s.	s.	PROPN
admet-2366	463	5	onoue	onoue	PROPN
admet-2366	463	6	,	,	PUNCT
admet-2366	463	7	s.	s.	PROPN
admet-2366	463	8	yamada	yamada	PROPN
admet-2366	463	9	,	,	PUNCT
admet-2366	463	10	h.k	h.k	PROPN
admet-2366	463	11	.	.	PROPN
admet-2366	463	12	chan	chan	PROPN
admet-2366	463	13	.	.	PUNCT
admet-2366	463	14	nanodrugs	nanodrug	NOUN
admet-2366	463	15	:	:	PUNCT
admet-2366	463	16	pharmacokinetics	pharmacokinetic	NOUN
admet-2366	463	17	and	and	CCONJ
admet-2366	463	18	safety	safety	NOUN
admet-2366	463	19	.	.	PUNCT
admet-2366	464	1	international	international	ADJ
admet-2366	464	2	journal	journal	NOUN
admet-2366	464	3	of	of	ADP
admet-2366	464	4	nanomedicine	nanomedicine	NOUN
admet-2366	464	5	9	9	NUM
admet-2366	464	6	(	(	PUNCT
admet-2366	464	7	2014	2014	NUM
admet-2366	464	8	)	)	PUNCT
admet-2366	464	9	1025	1025	NUM
admet-2366	464	10	-	-	SYM
admet-2366	464	11	1037	1037	NUM
admet-2366	464	12	.	.	PUNCT
admet-2366	465	1	https://doi.org/10.1186/s11671-018-2519-0	https://doi.org/10.1186/s11671-018-2519-0	NUM
admet-2366	465	2	.	.	PUNCT
admet-2366	466	1	[	[	X
admet-2366	466	2	19	19	NUM
admet-2366	466	3	]	]	X
admet-2366	466	4	s.	s.	PROPN
admet-2366	466	5	wang	wang	PROPN
admet-2366	466	6	,	,	PUNCT
admet-2366	466	7	r.	r.	PROPN
admet-2366	466	8	su	su	PROPN
admet-2366	466	9	,	,	PUNCT
admet-2366	466	10	s.	s.	PROPN
admet-2366	466	11	nie	nie	PROPN
admet-2366	466	12	,	,	PUNCT
admet-2366	466	13	m.	m.	NOUN
admet-2366	466	14	sun	sun	PROPN
admet-2366	466	15	,	,	PUNCT
admet-2366	466	16	j.	j.	PROPN
admet-2366	466	17	zhang	zhang	PROPN
admet-2366	466	18	,	,	PUNCT
admet-2366	466	19	d.	d.	PROPN
admet-2366	466	20	wu	wu	PROPN
admet-2366	466	21	,	,	PUNCT
admet-2366	466	22	n.	n.	PROPN
admet-2366	466	23	moustaid	moustaid	PROPN
admet-2366	466	24	-	-	PUNCT
admet-2366	466	25	moussa	moussa	PROPN
admet-2366	466	26	.	.	PUNCT
admet-2366	467	1	application	application	NOUN
admet-2366	467	2	of	of	ADP
admet-2366	467	3	nanotechnology	nanotechnology	NOUN
admet-2366	467	4	in	in	ADP
admet-2366	467	5	improving	improve	VERB
admet-2366	467	6	bioavailability	bioavailability	NOUN
admet-2366	467	7	and	and	CCONJ
admet-2366	467	8	bioactivity	bioactivity	NOUN
admet-2366	467	9	of	of	ADP
admet-2366	467	10	diet	diet	NOUN
admet-2366	467	11	-	-	PUNCT
admet-2366	467	12	derived	derive	VERB
admet-2366	467	13	phytochemicals	phytochemical	NOUN
admet-2366	467	14	.	.	PUNCT
admet-2366	468	1	the	the	DET
admet-2366	468	2	journal	journal	NOUN
admet-2366	468	3	of	of	ADP
admet-2366	468	4	nutritional	nutritional	ADJ
admet-2366	468	5	biochemistry	biochemistry	NOUN
admet-2366	468	6	25	25	NUM
admet-2366	468	7	(	(	PUNCT
admet-2366	468	8	2014	2014	NUM
admet-2366	468	9	)	)	PUNCT
admet-2366	468	10	363	363	NUM
admet-2366	468	11	-	-	SYM
admet-2366	468	12	376	376	NUM
admet-2366	468	13	.	.	PUNCT
admet-2366	469	1	https://doi.org/10.1016/j.jnutbio.2013.10.002	https://doi.org/10.1016/j.jnutbio.2013.10.002	NOUN
admet-2366	469	2	.	.	PUNCT
admet-2366	470	1	[	[	X
admet-2366	470	2	20	20	NUM
admet-2366	470	3	]	]	X
admet-2366	470	4	ba	ba	PROPN
admet-2366	470	5	.	.	PUNCT
admet-2366	471	1	chan	chan	PROPN
admet-2366	471	2	,	,	PUNCT
admet-2366	471	3	b.g.m	b.g.m	NOUN
admet-2366	471	4	.	.	PUNCT
admet-2366	472	1	hughes	hughe	NOUN
admet-2366	472	2	.	.	PUNCT
admet-2366	473	1	targeted	target	VERB
admet-2366	473	2	therapy	therapy	NOUN
admet-2366	473	3	for	for	ADP
admet-2366	473	4	non	non	ADJ
admet-2366	473	5	-	-	ADJ
admet-2366	473	6	small	small	ADJ
admet-2366	473	7	cell	cell	NOUN
admet-2366	473	8	lung	lung	NOUN
admet-2366	473	9	cancer	cancer	NOUN
admet-2366	473	10	:	:	PUNCT
admet-2366	473	11	current	current	ADJ
admet-2366	473	12	standards	standard	NOUN
admet-2366	473	13	and	and	CCONJ
admet-2366	473	14	the	the	DET
admet-2366	473	15	promise	promise	NOUN
admet-2366	473	16	of	of	ADP
admet-2366	473	17	the	the	DET
admet-2366	473	18	future	future	NOUN
admet-2366	473	19	.	.	PUNCT
admet-2366	474	1	translational	translational	ADJ
admet-2366	474	2	lung	lung	NOUN
admet-2366	474	3	cancer	cancer	NOUN
admet-2366	474	4	research	research	NOUN
admet-2366	474	5	4	4	NUM
admet-2366	474	6	(	(	PUNCT
admet-2366	474	7	2015	2015	NUM
admet-2366	474	8	)	)	PUNCT
admet-2366	474	9	36	36	NUM
admet-2366	474	10	-	-	SYM
admet-2366	474	11	54	54	NUM
admet-2366	474	12	.	.	PUNCT
admet-2366	474	13	https://doi.org/10.3978/j.issn.2218-6751.2014.05.01	https://doi.org/10.3978/j.issn.2218-6751.2014.05.01	PROPN
admet-2366	474	14	.	.	PUNCT
admet-2366	475	1	[	[	X
admet-2366	475	2	21	21	NUM
admet-2366	475	3	]	]	X
admet-2366	475	4	a.r	a.r	PROPN
admet-2366	475	5	.	.	PROPN
admet-2366	475	6	patel	patel	PROPN
admet-2366	475	7	,	,	PUNCT
admet-2366	475	8	m.b	m.b	PROPN
admet-2366	475	9	.	.	PROPN
admet-2366	475	10	chougule	chougule	PROPN
admet-2366	475	11	,	,	PUNCT
admet-2366	475	12	i.	i.	NOUN
admet-2366	475	13	townley	townley	PROPN
admet-2366	475	14	,	,	PUNCT
admet-2366	475	15	p.	p.	NOUN
admet-2366	475	16	ram	ram	PROPN
admet-2366	475	17	,	,	PUNCT
admet-2366	475	18	g.	g.	PROPN
admet-2366	475	19	wang	wang	PROPN
admet-2366	475	20	,	,	PUNCT
admet-2366	475	21	s.	s.	PROPN
admet-2366	475	22	mandip	mandip	PROPN
admet-2366	475	23	.	.	PUNCT
admet-2366	476	1	efficacy	efficacy	NOUN
admet-2366	476	2	of	of	ADP
admet-2366	476	3	aerosolized	aerosolize	VERB
admet-2366	476	4	celecoxib	celecoxib	PROPN
admet-2366	476	5	encapsulated	encapsulate	VERB
admet-2366	476	6	nanostructured	nanostructure	VERB
admet-2366	476	7	lipid	lipid	NOUN
admet-2366	476	8	carrier	carrier	NOUN
admet-2366	476	9	in	in	ADP
admet-2366	476	10	non	non	ADJ
admet-2366	476	11	-	-	ADJ
admet-2366	476	12	small	small	ADJ
admet-2366	476	13	cell	cell	NOUN
admet-2366	476	14	lung	lung	NOUN
admet-2366	476	15	cancer	cancer	NOUN
admet-2366	476	16	in	in	ADP
admet-2366	476	17	combination	combination	NOUN
admet-2366	476	18	with	with	ADP
admet-2366	476	19	docetaxel	docetaxel	PROPN
admet-2366	476	20	.	.	PUNCT
admet-2366	477	1	pharmaceutical	pharmaceutical	PROPN
admet-2366	477	2	research	research	NOUN
admet-2366	477	3	30	30	NUM
admet-2366	477	4	(	(	PUNCT
admet-2366	477	5	2013	2013	NUM
admet-2366	477	6	)	)	PUNCT
admet-2366	477	7	1435	1435	NUM
admet-2366	477	8	-	-	SYM
admet-2366	477	9	1446	1446	NUM
admet-2366	477	10	.	.	PUNCT
admet-2366	478	1	https://doi.org/10.1007/s11095-0130984-9	https://doi.org/10.1007/s11095-0130984-9	ADJ
admet-2366	478	2	.	.	PUNCT
admet-2366	479	1	[	[	X
admet-2366	479	2	22	22	NUM
admet-2366	479	3	]	]	X
admet-2366	479	4	a.r	a.r	PROPN
admet-2366	479	5	.	.	PROPN
admet-2366	479	6	patel	patel	PROPN
admet-2366	479	7	,	,	PUNCT
admet-2366	479	8	m.b	m.b	PROPN
admet-2366	479	9	.	.	PROPN
admet-2366	479	10	chougule	chougule	PROPN
admet-2366	479	11	,	,	PUNCT
admet-2366	479	12	e.	e.	PROPN
admet-2366	479	13	lim	lim	PROPN
admet-2366	479	14	,	,	PUNCT
admet-2366	479	15	k.p	k.p	PROPN
admet-2366	479	16	.	.	PROPN
admet-2366	479	17	francis	francis	PROPN
admet-2366	479	18	,	,	PUNCT
admet-2366	479	19	s.	s.	PROPN
admet-2366	479	20	safe	safe	PROPN
admet-2366	479	21	,	,	PUNCT
admet-2366	479	22	s.	s.	PROPN
admet-2366	479	23	mandip	mandip	PROPN
admet-2366	479	24	.	.	PUNCT
admet-2366	480	1	theranostic	theranostic	ADJ
admet-2366	480	2	tumor	tumor	NOUN
admet-2366	480	3	homing	home	VERB
admet-2366	480	4	nanocarriers	nanocarrier	NOUN
admet-2366	480	5	for	for	ADP
admet-2366	480	6	the	the	DET
admet-2366	480	7	treatment	treatment	NOUN
admet-2366	480	8	of	of	ADP
admet-2366	480	9	lung	lung	NOUN
admet-2366	480	10	cancer	cancer	NOUN
admet-2366	480	11	.	.	PUNCT
admet-2366	481	1	nanomedicine	nanomedicine	PROPN
admet-2366	481	2	:	:	PUNCT
admet-2366	481	3	nanotechnology	nanotechnology	NOUN
admet-2366	481	4	,	,	PUNCT
admet-2366	481	5	biology	biology	NOUN
admet-2366	481	6	and	and	CCONJ
admet-2366	481	7	medicine	medicine	NOUN
admet-2366	481	8	10	10	NUM
admet-2366	481	9	(	(	PUNCT
admet-2366	481	10	2014	2014	NUM
admet-2366	481	11	)	)	PUNCT
admet-2366	481	12	1053	1053	NUM
admet-2366	481	13	-	-	SYM
admet-2366	481	14	1063	1063	NUM
admet-2366	481	15	.	.	PUNCT
admet-2366	482	1	https://doi.org/10.1016/j.nano.2013.12.002	https://doi.org/10.1016/j.nano.2013.12.002	NOUN
admet-2366	482	2	.	.	PUNCT
admet-2366	483	1	[	[	X
admet-2366	483	2	23	23	NUM
admet-2366	483	3	]	]	PUNCT
admet-2366	483	4	t.	t.	PROPN
admet-2366	483	5	yamaguchi	yamaguchi	PROPN
admet-2366	483	6	,	,	PUNCT
admet-2366	483	7	s.	s.	PROPN
admet-2366	483	8	isogai	isogai	PROPN
admet-2366	483	9	,	,	PUNCT
admet-2366	483	10	t.	t.	PROPN
admet-2366	483	11	okamura	okamura	PROPN
admet-2366	483	12	,	,	PUNCT
admet-2366	483	13	s.	s.	PROPN
admet-2366	483	14	uozu	uozu	PROPN
admet-2366	483	15	,	,	PUNCT
admet-2366	483	16	y.	y.	PROPN
admet-2366	483	17	mieno	mieno	PROPN
admet-2366	483	18	,	,	PUNCT
admet-2366	483	19	t.	t.	PROPN
admet-2366	483	20	hoshino	hoshino	PROPN
admet-2366	483	21	,	,	PUNCT
admet-2366	483	22	y.	y.	PROPN
admet-2366	483	23	goto	goto	PROPN
admet-2366	483	24	,	,	PUNCT
admet-2366	483	25	m.	m.	PROPN
admet-2366	483	26	hayashi	hayashi	PROPN
admet-2366	483	27	,	,	PUNCT
admet-2366	483	28	t.	t.	PROPN
admet-2366	483	29	nakanishi	nakanishi	PROPN
admet-2366	483	30	,	,	PUNCT
admet-2366	483	31	k.	k.	PROPN
admet-2366	483	32	imaizumi	imaizumi	PROPN
admet-2366	483	33	.	.	PUNCT
admet-2366	484	1	pharmacokinetics	pharmacokinetic	NOUN
admet-2366	484	2	of	of	ADP
admet-2366	484	3	gefitinib	gefitinib	NOUN
admet-2366	484	4	in	in	ADP
admet-2366	484	5	a	a	DET
admet-2366	484	6	patient	patient	NOUN
admet-2366	484	7	with	with	ADP
admet-2366	484	8	non	non	ADJ
admet-2366	484	9	-	-	ADJ
admet-2366	484	10	small	small	ADJ
admet-2366	484	11	cell	cell	NOUN
admet-2366	484	12	lung	lung	NOUN
admet-2366	484	13	cancer	cancer	NOUN
admet-2366	484	14	undergoing	undergo	VERB
admet-2366	484	15	continuous	continuous	ADJ
admet-2366	484	16	ambulatory	ambulatory	ADJ
admet-2366	484	17	peritoneal	peritoneal	ADJ
admet-2366	484	18	dialysis	dialysis	NOUN
admet-2366	484	19	.	.	PUNCT
admet-2366	485	1	case	case	NOUN
admet-2366	485	2	reports	report	VERB
admet-2366	485	3	in	in	ADP
admet-2366	485	4	oncology	oncology	NOUN
admet-2366	485	5	8	8	NUM
admet-2366	485	6	(	(	PUNCT
admet-2366	485	7	2015	2015	NUM
admet-2366	485	8	)	)	PUNCT
admet-2366	485	9	78	78	NUM
admet-2366	485	10	-	-	SYM
admet-2366	485	11	82	82	NUM
admet-2366	485	12	.	.	PUNCT
admet-2366	486	1	https://doi.org/10.1159/000375485	https://doi.org/10.1159/000375485	NOUN
admet-2366	486	2	.	.	PUNCT
admet-2366	487	1	[	[	X
admet-2366	487	2	24	24	NUM
admet-2366	487	3	]	]	PUNCT
admet-2366	487	4	a.	a.	NOUN
admet-2366	487	5	verma	verma	PROPN
admet-2366	487	6	,	,	PUNCT
admet-2366	487	7	g.	g.	PROPN
admet-2366	487	8	sharma	sharma	PROPN
admet-2366	487	9	,	,	PUNCT
admet-2366	487	10	a.	a.	NOUN
admet-2366	487	11	jain	jain	PROPN
admet-2366	487	12	,	,	PUNCT
admet-2366	487	13	a.	a.	PROPN
admet-2366	487	14	tiwari	tiwari	PROPN
admet-2366	487	15	,	,	PUNCT
admet-2366	487	16	s.	s.	PROPN
admet-2366	487	17	saraf	saraf	PROPN
admet-2366	487	18	,	,	PUNCT
admet-2366	487	19	p.k	p.k	PROPN
admet-2366	487	20	.	.	PROPN
admet-2366	487	21	panda	panda	NOUN
admet-2366	487	22	,	,	PUNCT
admet-2366	487	23	o.p	o.p	PROPN
admet-2366	487	24	.	.	PROPN
admet-2366	487	25	katare	katare	PROPN
admet-2366	487	26	,	,	PUNCT
admet-2366	487	27	s.k	s.k	PROPN
admet-2366	487	28	.	.	PROPN
admet-2366	487	29	jain	jain	PROPN
admet-2366	487	30	.	.	PUNCT
admet-2366	488	1	systematic	systematic	ADJ
admet-2366	488	2	optimization	optimization	NOUN
admet-2366	488	3	of	of	ADP
admet-2366	488	4	cationic	cationic	ADJ
admet-2366	488	5	surface	surface	NOUN
admet-2366	488	6	engineered	engineer	VERB
admet-2366	488	7	mucoadhesive	mucoadhesive	ADJ
admet-2366	488	8	vesicles	vesicle	NOUN
admet-2366	488	9	employing	employ	VERB
admet-2366	488	10	design	design	NOUN
admet-2366	488	11	of	of	ADP
admet-2366	488	12	experiment	experiment	NOUN
admet-2366	488	13	(	(	PUNCT
admet-2366	488	14	doe	doe	NOUN
admet-2366	488	15	):	):	PUNCT
admet-2366	488	16	a	a	DET
admet-2366	488	17	preclinical	preclinical	ADJ
admet-2366	488	18	investigation	investigation	NOUN
admet-2366	488	19	.	.	PUNCT
admet-2366	489	1	international	international	ADJ
admet-2366	489	2	journal	journal	NOUN
admet-2366	489	3	of	of	ADP
admet-2366	489	4	biological	biological	ADJ
admet-2366	489	5	macromolecules	macromolecule	NOUN
admet-2366	489	6	133	133	NUM
admet-2366	489	7	(	(	PUNCT
admet-2366	489	8	2019	2019	NUM
admet-2366	489	9	)	)	PUNCT
admet-2366	489	10	1142	1142	NUM
admet-2366	489	11	-	-	SYM
admet-2366	489	12	1155	1155	NUM
admet-2366	489	13	.	.	PUNCT
admet-2366	490	1	https://doi.org/10.1016/j.ijbiomac.2019.04.118	https://doi.org/10.1016/j.ijbiomac.2019.04.118	VERB
admet-2366	490	2	.	.	PUNCT
admet-2366	491	1	https://doi.org/10.1186/s12951-014-0043-7	https://doi.org/10.1186/s12951-014-0043-7	VERB
admet-2366	491	2	https://doi.org/10.2147/ijn.s2.4.675	https://doi.org/10.2147/ijn.s2.4.675	PROPN
admet-2366	491	3	https://doi.org/10.21037/tlcr.2016.06.07	https://doi.org/10.21037/tlcr.2016.06.07	PUNCT
admet-2366	491	4	https://doi.org/10.2147/dddt.s6594	https://doi.org/10.2147/dddt.s6594	NOUN
admet-2366	491	5	https://doi.org/10.1007/s11095-015-1771-6	https://doi.org/10.1007/s11095-015-1771-6	NUM
admet-2366	491	6	https://doi.org/10.3390/cells3020304	https://doi.org/10.3390/cells3020304	PROPN
admet-2366	491	7	https://doi.org/10.2217/nnm.13.118	https://doi.org/10.2217/nnm.13.118	AUX
admet-2366	491	8	https://doi.org/10.2147/ijn.s68861	https://doi.org/10.2147/ijn.s68861	NUM
admet-2366	491	9	https://doi.org/10.4103/0366-6999.174484	https://doi.org/10.4103/0366-6999.174484	PROPN
admet-2366	491	10	https://doi.org/10.4103/0366-6999.174484	https://doi.org/10.4103/0366-6999.174484	VERB
admet-2366	491	11	https://doi.org/10.1186/s11671-018-2519-0	https://doi.org/10.1186/s11671-018-2519-0	PROPN
admet-2366	492	1	https://doi.org/10.1186/s11671-018-2519-0	https://doi.org/10.1186/s11671-018-2519-0	NUM
admet-2366	493	1	https://doi.org/10.1016/j.jnutbio.2013.10.002	https://doi.org/10.1016/j.jnutbio.2013.10.002	PRON
admet-2366	493	2	https://doi.org/10.3978/j.issn.2218-6751.2014.05.01	https://doi.org/10.3978/j.issn.2218-6751.2014.05.01	NOUN
admet-2366	493	3	https://doi.org/10.1007/s11095-013-0984-9	https://doi.org/10.1007/s11095-013-0984-9	NUM
admet-2366	493	4	https://doi.org/10.1007/s11095-013-0984-9	https://doi.org/10.1007/s11095-013-0984-9	NUM
admet-2366	493	5	https://doi.org/10.1016/j.nano.2013.12.002	https://doi.org/10.1016/j.nano.2013.12.002	NOUN
admet-2366	493	6	https://doi.org/10.1159/000375485	https://doi.org/10.1159/000375485	NOUN
admet-2366	493	7	https://doi.org/10.1016/j.ijbiomac.2019.04.118	https://doi.org/10.1016/j.ijbiomac.2019.04.118	VERB
admet-2366	493	8	admet	admet	PROPN
admet-2366	493	9	&	&	CCONJ
admet-2366	493	10	dmpk	dmpk	PROPN
admet-2366	493	11	12(4	12(4	PROPN
admet-2366	493	12	)	)	PUNCT
admet-2366	493	13	(	(	PUNCT
admet-2366	493	14	2024	2024	NUM
admet-2366	493	15	)	)	PUNCT
admet-2366	493	16	657	657	NUM
admet-2366	493	17	-	-	SYM
admet-2366	493	18	677	677	NUM
admet-2366	493	19	optimizing	optimizing	NOUN
admet-2366	493	20	gefitinib	gefitinib	NOUN
admet-2366	493	21	nanoliposomes	nanoliposomes	ADV
admet-2366	493	22	doi	doi	ADV
admet-2366	493	23	:	:	PUNCT
admet-2366	493	24	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	NOUN
admet-2366	493	25	675	675	NUM
admet-2366	494	1	[	[	X
admet-2366	494	2	25	25	NUM
admet-2366	494	3	]	]	X
admet-2366	494	4	ferreira	ferreira	PROPN
admet-2366	494	5	slc	slc	PROPN
admet-2366	494	6	,	,	PUNCT
admet-2366	494	7	bruns	bruns	PROPN
admet-2366	494	8	re	re	PROPN
admet-2366	494	9	,	,	PUNCT
admet-2366	494	10	ferreira	ferreira	PROPN
admet-2366	494	11	hs	hs	PROPN
admet-2366	494	12	,	,	PUNCT
admet-2366	494	13	g.d	g.d	PROPN
admet-2366	494	14	.	.	PROPN
admet-2366	495	1	matos	matos	PROPN
admet-2366	495	2	,	,	PUNCT
admet-2366	495	3	j.m	j.m	PROPN
admet-2366	495	4	.	.	PROPN
admet-2366	495	5	david	david	PROPN
admet-2366	495	6	,	,	PUNCT
admet-2366	495	7	g.c	g.c	PROPN
admet-2366	495	8	.	.	PROPN
admet-2366	495	9	brandão	brandão	PROPN
admet-2366	495	10	,	,	PUNCT
admet-2366	495	11	e.p	e.p	PROPN
admet-2366	495	12	.	.	PROPN
admet-2366	495	13	da	da	PROPN
admet-2366	495	14	silva	silva	PROPN
admet-2366	495	15	,	,	PUNCT
admet-2366	495	16	l.a	l.a	PROPN
admet-2366	495	17	.	.	PROPN
admet-2366	495	18	portugal	portugal	PROPN
admet-2366	495	19	,	,	PUNCT
admet-2366	495	20	p.s	p.s	PROPN
admet-2366	495	21	.	.	PROPN
admet-2366	495	22	dos	do	NOUN
admet-2366	495	23	reis	reis	NOUN
admet-2366	495	24	,	,	PUNCT
admet-2366	495	25	a.s	a.s	PROPN
admet-2366	495	26	.	.	PROPN
admet-2366	495	27	souza	souza	PROPN
admet-2366	495	28	,	,	PUNCT
admet-2366	495	29	w.n	w.n	PROPN
admet-2366	495	30	.	.	PROPN
admet-2366	495	31	dos	dos	PROPN
admet-2366	495	32	santos	santos	PROPN
admet-2366	495	33	.	.	PUNCT
admet-2366	496	1	box	box	NOUN
admet-2366	496	2	-	-	PUNCT
admet-2366	496	3	behnken	behnken	VERB
admet-2366	496	4	design	design	NOUN
admet-2366	496	5	:	:	PUNCT
admet-2366	496	6	an	an	DET
admet-2366	496	7	alternative	alternative	NOUN
admet-2366	496	8	for	for	ADP
admet-2366	496	9	the	the	DET
admet-2366	496	10	optimization	optimization	NOUN
admet-2366	496	11	of	of	ADP
admet-2366	496	12	analytical	analytical	ADJ
admet-2366	496	13	methods	method	NOUN
admet-2366	496	14	.	.	PUNCT
admet-2366	497	1	analytica	analytica	PROPN
admet-2366	497	2	chimica	chimica	PROPN
admet-2366	497	3	acta	acta	PROPN
admet-2366	497	4	597	597	NUM
admet-2366	497	5	(	(	PUNCT
admet-2366	497	6	2007	2007	NUM
admet-2366	497	7	)	)	PUNCT
admet-2366	497	8	179	179	NUM
admet-2366	497	9	-	-	SYM
admet-2366	497	10	186	186	NUM
admet-2366	497	11	.	.	PUNCT
admet-2366	498	1	https://doi.org/10.1016/j.aca.2007.07.011	https://doi.org/10.1016/j.aca.2007.07.011	PROPN
admet-2366	498	2	.	.	PUNCT
admet-2366	499	1	[	[	X
admet-2366	499	2	26	26	NUM
admet-2366	499	3	]	]	PUNCT
admet-2366	499	4	s.	s.	PROPN
admet-2366	499	5	nandhakumar	nandhakumar	PROPN
admet-2366	499	6	,	,	PUNCT
admet-2366	499	7	m.	m.	NOUN
admet-2366	499	8	dhanaraju	dhanaraju	PROPN
admet-2366	499	9	,	,	PUNCT
admet-2366	499	10	c.	c.	PROPN
admet-2366	499	11	pavankumar	pavankumar	PROPN
admet-2366	499	12	,	,	PUNCT
admet-2366	499	13	v.	v.	PROPN
admet-2366	499	14	sundar	sundar	NOUN
admet-2366	499	15	.	.	PUNCT
admet-2366	500	1	optimization	optimization	NOUN
admet-2366	500	2	of	of	ADP
admet-2366	500	3	paclitaxel	paclitaxel	PROPN
admet-2366	500	4	loaded	load	VERB
admet-2366	500	5	poly	poly	ADJ
admet-2366	500	6	(	(	PUNCT
admet-2366	500	7	caprolactone	caprolactone	NOUN
admet-2366	500	8	)	)	PUNCT
admet-2366	500	9	nanoparticles	nanoparticle	NOUN
admet-2366	500	10	using	use	VERB
admet-2366	500	11	box	box	NOUN
admet-2366	500	12	behnken	behnken	NOUN
admet-2366	500	13	design	design	NOUN
admet-2366	500	14	design	design	NOUN
admet-2366	500	15	.	.	PUNCT
admet-2366	501	1	beni	beni	ADJ
admet-2366	501	2	-	-	ADJ
admet-2366	501	3	suef	suef	ADJ
admet-2366	501	4	university	university	NOUN
admet-2366	501	5	journal	journal	NOUN
admet-2366	501	6	of	of	ADP
admet-2366	501	7	basic	basic	ADJ
admet-2366	501	8	and	and	CCONJ
admet-2366	501	9	applied	apply	VERB
admet-2366	501	10	sciences	science	NOUN
admet-2366	501	11	6	6	NUM
admet-2366	501	12	(	(	PUNCT
admet-2366	501	13	2017	2017	NUM
admet-2366	501	14	)	)	PUNCT
admet-2366	501	15	362	362	NUM
admet-2366	501	16	-	-	SYM
admet-2366	501	17	373	373	NUM
admet-2366	501	18	.	.	PUNCT
admet-2366	501	19	https://doi.org/10.1016/j.bjbas.2017.06.002	https://doi.org/10.1016/j.bjbas.2017.06.002	NOUN
admet-2366	501	20	.	.	PUNCT
admet-2366	502	1	[	[	X
admet-2366	502	2	27	27	NUM
admet-2366	502	3	]	]	X
admet-2366	502	4	g.e	g.e	PROPN
admet-2366	502	5	.	.	PROPN
admet-2366	502	6	box	box	PROPN
admet-2366	502	7	,	,	PUNCT
admet-2366	502	8	d.w	d.w	PROPN
admet-2366	502	9	.	.	PROPN
admet-2366	502	10	behnken	behnken	PROPN
admet-2366	502	11	.	.	PUNCT
admet-2366	503	1	some	some	DET
admet-2366	503	2	new	new	ADJ
admet-2366	503	3	three	three	NUM
admet-2366	503	4	level	level	NOUN
admet-2366	503	5	designs	design	NOUN
admet-2366	503	6	for	for	ADP
admet-2366	503	7	the	the	DET
admet-2366	503	8	study	study	NOUN
admet-2366	503	9	of	of	ADP
admet-2366	503	10	quantitative	quantitative	ADJ
admet-2366	503	11	variables	variable	NOUN
admet-2366	503	12	.	.	PUNCT
admet-2366	504	1	technometrics	technometric	NOUN
admet-2366	504	2	2	2	NUM
admet-2366	504	3	(	(	PUNCT
admet-2366	504	4	1960	1960	NUM
admet-2366	504	5	)	)	PUNCT
admet-2366	504	6	455	455	NUM
admet-2366	504	7	-	-	SYM
admet-2366	504	8	475	475	NUM
admet-2366	504	9	.	.	PUNCT
admet-2366	505	1	https://doi.org/10.1080/00401706.1960.10489912	https://doi.org/10.1080/00401706.1960.10489912	PROPN
admet-2366	505	2	.	.	PUNCT
admet-2366	506	1	[	[	X
admet-2366	506	2	28	28	NUM
admet-2366	506	3	]	]	X
admet-2366	506	4	s.n	s.n	PROPN
admet-2366	506	5	.	.	PROPN
admet-2366	506	6	azizi	azizi	PROPN
admet-2366	506	7	,	,	PUNCT
admet-2366	506	8	n.	n.	PROPN
admet-2366	506	9	asemi	asemi	PROPN
admet-2366	506	10	.	.	PUNCT
admet-2366	507	1	a	a	DET
admet-2366	507	2	box	box	NOUN
admet-2366	507	3	-	-	PUNCT
admet-2366	507	4	behnken	behnken	VERB
admet-2366	507	5	design	design	NOUN
admet-2366	507	6	for	for	ADP
admet-2366	507	7	determining	determine	VERB
admet-2366	507	8	the	the	DET
admet-2366	507	9	optimum	optimum	ADJ
admet-2366	507	10	experimental	experimental	ADJ
admet-2366	507	11	condition	condition	NOUN
admet-2366	507	12	of	of	ADP
admet-2366	507	13	the	the	DET
admet-2366	507	14	fungicide	fungicide	NOUN
admet-2366	507	15	(	(	PUNCT
admet-2366	507	16	vapam	vapam	NOUN
admet-2366	507	17	)	)	PUNCT
admet-2366	507	18	sorption	sorption	NOUN
admet-2366	507	19	onto	onto	ADP
admet-2366	507	20	soil	soil	NOUN
admet-2366	507	21	modified	modify	VERB
admet-2366	507	22	with	with	ADP
admet-2366	507	23	perlite	perlite	NOUN
admet-2366	507	24	.	.	PUNCT
admet-2366	508	1	journal	journal	PROPN
admet-2366	508	2	of	of	ADP
admet-2366	508	3	environmental	environmental	ADJ
admet-2366	508	4	science	science	NOUN
admet-2366	508	5	and	and	CCONJ
admet-2366	508	6	health	health	NOUN
admet-2366	508	7	,	,	PUNCT
admet-2366	508	8	part	part	NOUN
admet-2366	508	9	b	b	PROPN
admet-2366	508	10	47	47	NUM
admet-2366	508	11	(	(	PUNCT
admet-2366	508	12	2012	2012	NUM
admet-2366	508	13	)	)	PUNCT
admet-2366	508	14	692	692	NUM
admet-2366	508	15	-	-	SYM
admet-2366	508	16	699	699	NUM
admet-2366	508	17	.	.	PUNCT
admet-2366	509	1	https://doi.org/10.1080/03601234.2012.669260	https://doi.org/10.1080/03601234.2012.669260	NOUN
admet-2366	509	2	.	.	PUNCT
admet-2366	510	1	[	[	X
admet-2366	510	2	29	29	NUM
admet-2366	510	3	]	]	PUNCT
admet-2366	510	4	x.	x.	PROPN
admet-2366	510	5	cao	cao	PROPN
admet-2366	510	6	,	,	PUNCT
admet-2366	510	7	d.	d.	PROPN
admet-2366	510	8	hou	hou	PROPN
admet-2366	510	9	,	,	PUNCT
admet-2366	510	10	l.	l.	PROPN
admet-2366	510	11	wang	wang	PROPN
admet-2366	510	12	,	,	PUNCT
admet-2366	510	13	s.	s.	PROPN
admet-2366	510	14	li	li	PROPN
admet-2366	510	15	,	,	PUNCT
admet-2366	510	16	s.	s.	PROPN
admet-2366	510	17	sun	sun	PROPN
admet-2366	510	18	,	,	PUNCT
admet-2366	510	19	q.	q.	PROPN
admet-2366	510	20	ping	ping	PROPN
admet-2366	510	21	,	,	PUNCT
admet-2366	510	22	y.	y.	PROPN
admet-2366	510	23	xu	xu	PROPN
admet-2366	510	24	.	.	PUNCT
admet-2366	511	1	effects	effect	NOUN
admet-2366	511	2	and	and	CCONJ
admet-2366	511	3	molecular	molecular	ADJ
admet-2366	511	4	mechanism	mechanism	NOUN
admet-2366	511	5	of	of	ADP
admet-2366	511	6	chitosancoated	chitosancoate	VERB
admet-2366	511	7	levodopa	levodopa	NOUN
admet-2366	511	8	nanoliposomes	nanoliposome	NOUN
admet-2366	511	9	on	on	ADP
admet-2366	511	10	behavior	behavior	NOUN
admet-2366	511	11	of	of	ADP
admet-2366	511	12	dyskinesia	dyskinesia	NOUN
admet-2366	511	13	rats	rat	NOUN
admet-2366	511	14	.	.	PUNCT
admet-2366	512	1	biological	biological	ADJ
admet-2366	512	2	research	research	NOUN
admet-2366	512	3	49	49	NUM
admet-2366	512	4	(	(	PUNCT
admet-2366	512	5	2016	2016	NUM
admet-2366	512	6	)	)	PUNCT
admet-2366	512	7	32	32	NUM
admet-2366	512	8	-	-	SYM
admet-2366	512	9	41	41	NUM
admet-2366	512	10	.	.	PUNCT
admet-2366	513	1	https://doi.org/10.1186/s40659-016-0093-4	https://doi.org/10.1186/s40659-016-0093-4	PROPN
admet-2366	513	2	.	.	PUNCT
admet-2366	514	1	[	[	X
admet-2366	514	2	30	30	NUM
admet-2366	514	3	]	]	X
admet-2366	514	4	s.	s.	PROPN
admet-2366	514	5	rohilla	rohilla	PROPN
admet-2366	514	6	,	,	PUNCT
admet-2366	514	7	h.	h.	PROPN
admet-2366	514	8	dureja	dureja	PROPN
admet-2366	514	9	.	.	PUNCT
admet-2366	515	1	effect	effect	NOUN
admet-2366	515	2	of	of	ADP
admet-2366	515	3	chitosan	chitosan	NOUN
admet-2366	515	4	coating	coating	NOUN
admet-2366	515	5	on	on	ADP
admet-2366	515	6	the	the	DET
admet-2366	515	7	physiochemical	physiochemical	ADJ
admet-2366	515	8	characteristics	characteristic	NOUN
admet-2366	515	9	of	of	ADP
admet-2366	515	10	gefitinib	gefitinib	NOUN
admet-2366	515	11	loaded	load	VERB
admet-2366	515	12	nanoliposomes	nanoliposome	NOUN
admet-2366	515	13	.	.	PUNCT
admet-2366	516	1	international	international	ADJ
admet-2366	516	2	journal	journal	PROPN
admet-2366	516	3	of	of	ADP
admet-2366	516	4	pharmaceutical	pharmaceutical	NOUN
admet-2366	516	5	sciences	science	NOUN
admet-2366	516	6	and	and	CCONJ
admet-2366	516	7	research	research	NOUN
admet-2366	516	8	9	9	NUM
admet-2366	516	9	(	(	PUNCT
admet-2366	516	10	2018	2018	NUM
admet-2366	516	11	)	)	PUNCT
admet-2366	516	12	10001013	10001013	NUM
admet-2366	516	13	.	.	PUNCT
admet-2366	517	1	https://doi.org/10.13040/ijpsr.0975-8232.9(12).5098-10	https://doi.org/10.13040/ijpsr.0975-8232.9(12).5098-10	X
admet-2366	517	2	.	.	PUNCT
admet-2366	518	1	[	[	X
admet-2366	518	2	31	31	NUM
admet-2366	518	3	]	]	PUNCT
admet-2366	518	4	c.	c.	PROPN
admet-2366	518	5	dong	dong	PROPN
admet-2366	518	6	,	,	PUNCT
admet-2366	518	7	j.a	j.a	PROPN
admet-2366	518	8	.	.	PROPN
admet-2366	518	9	rogers	rogers	PROPN
admet-2366	518	10	.	.	PUNCT
admet-2366	518	11	polymer	polymer	NOUN
admet-2366	518	12	-	-	PUNCT
admet-2366	518	13	coated	coat	VERB
admet-2366	518	14	liposomes	liposome	NOUN
admet-2366	518	15	:	:	PUNCT
admet-2366	518	16	stability	stability	NOUN
admet-2366	518	17	and	and	CCONJ
admet-2366	518	18	release	release	NOUN
admet-2366	518	19	of	of	ADP
admet-2366	518	20	asa	asa	PROPN
admet-2366	518	21	from	from	ADP
admet-2366	518	22	carboxymethyl	carboxymethyl	ADJ
admet-2366	518	23	chitin	chitin	NOUN
admet-2366	518	24	-	-	PUNCT
admet-2366	518	25	coated	coat	VERB
admet-2366	518	26	liposomes	liposome	NOUN
admet-2366	518	27	.	.	PUNCT
admet-2366	519	1	journal	journal	PROPN
admet-2366	519	2	of	of	ADP
admet-2366	519	3	controlled	control	VERB
admet-2366	519	4	release	release	NOUN
admet-2366	519	5	17	17	NUM
admet-2366	519	6	(	(	PUNCT
admet-2366	519	7	1991	1991	NUM
admet-2366	519	8	)	)	PUNCT
admet-2366	519	9	217	217	NUM
admet-2366	519	10	-	-	SYM
admet-2366	519	11	224	224	NUM
admet-2366	519	12	.	.	PUNCT
admet-2366	520	1	https://doi.org/10.1016/0168-3659(91)90140-9	https://doi.org/10.1016/0168-3659(91)90140-9	NOUN
admet-2366	520	2	.	.	PUNCT
admet-2366	521	1	[	[	X
admet-2366	521	2	32	32	NUM
admet-2366	521	3	]	]	PUNCT
admet-2366	521	4	c.	c.	PROPN
admet-2366	521	5	dai	dai	PROPN
admet-2366	521	6	,	,	PUNCT
admet-2366	521	7	b.	b.	PROPN
admet-2366	521	8	wang	wang	PROPN
admet-2366	521	9	,	,	PUNCT
admet-2366	521	10	h.	h.	PROPN
admet-2366	521	11	zhao	zhao	PROPN
admet-2366	521	12	,	,	PUNCT
admet-2366	521	13	b.	b.	PROPN
admet-2366	521	14	li	li	PROPN
admet-2366	521	15	,	,	PUNCT
admet-2366	521	16	j.	j.	PROPN
admet-2366	521	17	wang	wang	PROPN
admet-2366	521	18	.	.	PUNCT
admet-2366	521	19	preparation	preparation	NOUN
admet-2366	521	20	and	and	CCONJ
admet-2366	521	21	characterization	characterization	NOUN
admet-2366	521	22	of	of	ADP
admet-2366	521	23	liposomes	liposome	NOUN
admet-2366	521	24	-	-	PUNCT
admet-2366	521	25	in	in	ADP
admet-2366	521	26	-	-	PUNCT
admet-2366	521	27	alginate	alginate	NOUN
admet-2366	521	28	(	(	PUNCT
admet-2366	521	29	lia	lia	PROPN
admet-2366	521	30	)	)	PUNCT
admet-2366	521	31	for	for	ADP
admet-2366	521	32	protein	protein	NOUN
admet-2366	521	33	delivery	delivery	NOUN
admet-2366	521	34	system	system	NOUN
admet-2366	521	35	.	.	PUNCT
admet-2366	522	1	colloids	colloid	NOUN
admet-2366	522	2	and	and	CCONJ
admet-2366	522	3	surfaces	surface	NOUN
admet-2366	522	4	b	b	NUM
admet-2366	522	5	:	:	PUNCT
admet-2366	522	6	biointerfaces	biointerface	NOUN
admet-2366	522	7	47	47	NUM
admet-2366	522	8	(	(	PUNCT
admet-2366	522	9	2006	2006	NUM
admet-2366	522	10	)	)	PUNCT
admet-2366	522	11	205	205	NUM
admet-2366	522	12	-	-	SYM
admet-2366	522	13	210	210	NUM
admet-2366	522	14	.	.	PUNCT
admet-2366	523	1	https://doi.org/10.1016/j.colsurfb.2005.07.013	https://doi.org/10.1016/j.colsurfb.2005.07.013	X
admet-2366	523	2	.	.	PUNCT
admet-2366	524	1	[	[	X
admet-2366	524	2	33	33	NUM
admet-2366	524	3	]	]	PUNCT
admet-2366	524	4	m.	m.	PROPN
admet-2366	524	5	hasan	hasan	PROPN
admet-2366	524	6	,	,	PUNCT
admet-2366	524	7	k.	k.	PROPN
admet-2366	524	8	elkhoury	elkhoury	PROPN
admet-2366	524	9	,	,	PUNCT
admet-2366	524	10	c.j.f	c.j.f	NOUN
admet-2366	524	11	.	.	PUNCT
admet-2366	525	1	kahn	kahn	PROPN
admet-2366	525	2	,	,	PUNCT
admet-2366	525	3	e.	e.	PROPN
admet-2366	525	4	arab	arab	PROPN
admet-2366	525	5	-	-	PUNCT
admet-2366	525	6	tehrany	tehrany	NOUN
admet-2366	525	7	,	,	PUNCT
admet-2366	525	8	m.	m.	NOUN
admet-2366	525	9	linder	linder	PROPN
admet-2366	525	10	.	.	PUNCT
admet-2366	525	11	preparation	preparation	NOUN
admet-2366	525	12	,	,	PUNCT
admet-2366	525	13	characterization	characterization	NOUN
admet-2366	525	14	,	,	PUNCT
admet-2366	525	15	and	and	CCONJ
admet-2366	525	16	release	release	VERB
admet-2366	525	17	kinetics	kinetic	NOUN
admet-2366	525	18	of	of	ADP
admet-2366	525	19	chitosan	chitosan	NOUN
admet-2366	525	20	-	-	PUNCT
admet-2366	525	21	coated	coat	VERB
admet-2366	525	22	nanoliposomes	nanoliposome	NOUN
admet-2366	525	23	encapsulating	encapsulate	VERB
admet-2366	525	24	curcumin	curcumin	NOUN
admet-2366	525	25	in	in	ADP
admet-2366	525	26	simulated	simulated	ADJ
admet-2366	525	27	environments	environment	NOUN
admet-2366	525	28	.	.	PUNCT
admet-2366	526	1	molecules	molecule	NOUN
admet-2366	526	2	24	24	NUM
admet-2366	526	3	(	(	PUNCT
admet-2366	526	4	2019	2019	NUM
admet-2366	526	5	)	)	PUNCT
admet-2366	526	6	2023	2023	NUM
admet-2366	526	7	.	.	PUNCT
admet-2366	527	1	https://doi.org/10.3390/molecules24102023	https://doi.org/10.3390/molecules24102023	NOUN
admet-2366	527	2	.	.	PUNCT
admet-2366	528	1	[	[	X
admet-2366	528	2	34	34	NUM
admet-2366	528	3	]	]	X
admet-2366	528	4	m.	m.	PROPN
admet-2366	528	5	hasan	hasan	PROPN
admet-2366	528	6	,	,	PUNCT
admet-2366	528	7	k.	k.	PROPN
admet-2366	528	8	elkhoury	elkhoury	PROPN
admet-2366	528	9	,	,	PUNCT
admet-2366	528	10	n.	n.	PROPN
admet-2366	528	11	belhaj	belhaj	PROPN
admet-2366	528	12	,	,	PUNCT
admet-2366	528	13	c.	c.	PROPN
admet-2366	528	14	kahn	kahn	PROPN
admet-2366	528	15	,	,	PUNCT
admet-2366	528	16	a.	a.	NOUN
admet-2366	528	17	tamayol	tamayol	PROPN
admet-2366	528	18	,	,	PUNCT
admet-2366	528	19	m.	m.	NOUN
admet-2366	528	20	barberi	barberi	NOUN
admet-2366	528	21	-	-	PUNCT
admet-2366	528	22	heyob	heyob	PROPN
admet-2366	528	23	,	,	PUNCT
admet-2366	528	24	e.	e.	PROPN
admet-2366	528	25	arab	arab	PROPN
admet-2366	528	26	-	-	PUNCT
admet-2366	528	27	tehrany	tehrany	NOUN
admet-2366	528	28	,	,	PUNCT
admet-2366	528	29	m.	m.	NOUN
admet-2366	528	30	linder	linder	PROPN
admet-2366	528	31	.	.	PUNCT
admet-2366	529	1	growth	growth	NOUN
admet-2366	529	2	-	-	PUNCT
admet-2366	529	3	inhibitory	inhibitory	ADJ
admet-2366	529	4	effect	effect	NOUN
admet-2366	529	5	of	of	ADP
admet-2366	529	6	chitosan	chitosan	NOUN
admet-2366	529	7	-	-	PUNCT
admet-2366	529	8	coated	coat	VERB
admet-2366	529	9	liposomes	liposome	NOUN
admet-2366	529	10	encapsulating	encapsulate	VERB
admet-2366	529	11	curcumin	curcumin	NOUN
admet-2366	529	12	on	on	ADP
admet-2366	529	13	mcf-7	mcf-7	PUNCT
admet-2366	529	14	breast	breast	NOUN
admet-2366	529	15	cancer	cancer	NOUN
admet-2366	529	16	cells	cell	NOUN
admet-2366	529	17	.	.	PUNCT
admet-2366	530	1	marine	marine	ADJ
admet-2366	530	2	drugs	drug	NOUN
admet-2366	530	3	18	18	NUM
admet-2366	530	4	(	(	PUNCT
admet-2366	530	5	2020	2020	NUM
admet-2366	530	6	)	)	PUNCT
admet-2366	530	7	217	217	NUM
admet-2366	530	8	.	.	PUNCT
admet-2366	531	1	https://doi.org/10.3390/md18040217	https://doi.org/10.3390/md18040217	X
admet-2366	531	2	.	.	PUNCT
admet-2366	532	1	[	[	X
admet-2366	532	2	35	35	NUM
admet-2366	532	3	]	]	X
admet-2366	532	4	s.	s.	PROPN
admet-2366	532	5	rohilla	rohilla	PROPN
admet-2366	532	6	,	,	PUNCT
admet-2366	532	7	h.	h.	PROPN
admet-2366	532	8	dureja	dureja	PROPN
admet-2366	532	9	.	.	PUNCT
admet-2366	533	1	recent	recent	ADJ
admet-2366	533	2	patents	patent	NOUN
admet-2366	533	3	,	,	PUNCT
admet-2366	533	4	formulation	formulation	NOUN
admet-2366	533	5	and	and	CCONJ
admet-2366	533	6	characterization	characterization	NOUN
admet-2366	533	7	of	of	ADP
admet-2366	533	8	nanoliposomes	nanoliposome	NOUN
admet-2366	533	9	.	.	PUNCT
admet-2366	534	1	recent	recent	ADJ
admet-2366	534	2	patents	patent	NOUN
admet-2366	534	3	in	in	ADP
admet-2366	534	4	drug	drug	NOUN
admet-2366	534	5	delivery	delivery	NOUN
admet-2366	534	6	and	and	CCONJ
admet-2366	534	7	formulations	formulation	NOUN
admet-2366	534	8	9	9	NUM
admet-2366	534	9	(	(	PUNCT
admet-2366	534	10	2015	2015	NUM
admet-2366	534	11	)	)	PUNCT
admet-2366	534	12	213	213	NUM
admet-2366	534	13	-	-	SYM
admet-2366	534	14	224	224	NUM
admet-2366	534	15	.	.	PUNCT
admet-2366	535	1	https://doi.org/10.2174/1872211309666150629105900	https://doi.org/10.2174/1872211309666150629105900	X
admet-2366	535	2	.	.	PUNCT
admet-2366	536	1	[	[	X
admet-2366	536	2	36	36	NUM
admet-2366	536	3	]	]	X
admet-2366	536	4	b.	b.	PROPN
admet-2366	536	5	ding	ding	PROPN
admet-2366	536	6	,	,	PUNCT
admet-2366	536	7	x.	x.	PROPN
admet-2366	536	8	zhang	zhang	PROPN
admet-2366	536	9	,	,	PUNCT
admet-2366	536	10	k.	k.	PROPN
admet-2366	536	11	hayat	hayat	PROPN
admet-2366	536	12	,	,	PUNCT
admet-2366	536	13	s.	s.	PROPN
admet-2366	536	14	xia	xia	PROPN
admet-2366	536	15	,	,	PUNCT
admet-2366	536	16	c.	c.	PROPN
admet-2366	536	17	jia	jia	PROPN
admet-2366	536	18	,	,	PUNCT
admet-2366	536	19	m.	m.	PROPN
admet-2366	536	20	xie	xie	PROPN
admet-2366	536	21	,	,	PUNCT
admet-2366	536	22	c.	c.	PROPN
admet-2366	536	23	liu	liu	PROPN
admet-2366	536	24	.	.	PUNCT
admet-2366	537	1	preparation	preparation	NOUN
admet-2366	537	2	,	,	PUNCT
admet-2366	537	3	characterization	characterization	NOUN
admet-2366	537	4	and	and	CCONJ
admet-2366	537	5	the	the	DET
admet-2366	537	6	stability	stability	NOUN
admet-2366	537	7	of	of	ADP
admet-2366	537	8	ferrous	ferrous	ADJ
admet-2366	537	9	glycinate	glycinate	NOUN
admet-2366	537	10	nanoliposomes	nanoliposome	NOUN
admet-2366	537	11	.	.	PUNCT
admet-2366	538	1	journal	journal	PROPN
admet-2366	538	2	of	of	ADP
admet-2366	538	3	food	food	NOUN
admet-2366	538	4	engineering	engineering	NOUN
admet-2366	538	5	102	102	NUM
admet-2366	538	6	(	(	PUNCT
admet-2366	538	7	2011	2011	NUM
admet-2366	538	8	)	)	PUNCT
admet-2366	538	9	202	202	NUM
admet-2366	538	10	-	-	SYM
admet-2366	538	11	208	208	NUM
admet-2366	538	12	.	.	PUNCT
admet-2366	539	1	https://doi.org/10.1016/j.jfoodeng.2010.08.022	https://doi.org/10.1016/j.jfoodeng.2010.08.022	NOUN
admet-2366	539	2	.	.	PUNCT
admet-2366	540	1	[	[	X
admet-2366	540	2	37	37	NUM
admet-2366	540	3	]	]	X
admet-2366	540	4	m.m	m.m	PROPN
admet-2366	540	5	.	.	PROPN
admet-2366	540	6	mady	mady	PROPN
admet-2366	540	7	,	,	PUNCT
admet-2366	540	8	m.m	m.m	PROPN
admet-2366	540	9	.	.	PROPN
admet-2366	540	10	darwish	darwish	PROPN
admet-2366	540	11	.	.	PUNCT
admet-2366	540	12	effect	effect	NOUN
admet-2366	540	13	of	of	ADP
admet-2366	540	14	chitosan	chitosan	NOUN
admet-2366	540	15	coating	coating	NOUN
admet-2366	540	16	on	on	ADP
admet-2366	540	17	the	the	DET
admet-2366	540	18	characteristics	characteristic	NOUN
admet-2366	540	19	of	of	ADP
admet-2366	540	20	dppc	dppc	ADJ
admet-2366	540	21	liposomes	liposome	NOUN
admet-2366	540	22	.	.	PUNCT
admet-2366	541	1	journal	journal	NOUN
admet-2366	541	2	of	of	ADP
admet-2366	541	3	advanced	advanced	ADJ
admet-2366	541	4	research	research	NOUN
admet-2366	541	5	1	1	NUM
admet-2366	541	6	(	(	PUNCT
admet-2366	541	7	2010	2010	NUM
admet-2366	541	8	)	)	PUNCT
admet-2366	541	9	187	187	NUM
admet-2366	541	10	-	-	SYM
admet-2366	541	11	191	191	NUM
admet-2366	541	12	.	.	PUNCT
admet-2366	542	1	https://doi.org/10.1016/j.jare.2010.05.008	https://doi.org/10.1016/j.jare.2010.05.008	NOUN
admet-2366	542	2	.	.	PUNCT
admet-2366	543	1	[	[	X
admet-2366	543	2	38	38	NUM
admet-2366	543	3	]	]	X
admet-2366	543	4	g.h	g.h	PROPN
admet-2366	543	5	.	.	PROPN
admet-2366	543	6	shin	shin	PROPN
admet-2366	543	7	,	,	PUNCT
admet-2366	543	8	s.k	s.k	PROPN
admet-2366	543	9	.	.	PROPN
admet-2366	543	10	chung	chung	PROPN
admet-2366	543	11	,	,	PUNCT
admet-2366	543	12	j.t	j.t	PROPN
admet-2366	543	13	.	.	PROPN
admet-2366	543	14	kim	kim	PROPN
admet-2366	543	15	,	,	PUNCT
admet-2366	543	16	h.j	h.j	PROPN
admet-2366	543	17	joung	joung	PROPN
admet-2366	543	18	,	,	PUNCT
admet-2366	543	19	h.j	h.j	PROPN
admet-2366	543	20	.	.	PROPN
admet-2366	543	21	park	park	PROPN
admet-2366	543	22	.	.	PUNCT
admet-2366	544	1	preparation	preparation	NOUN
admet-2366	544	2	of	of	ADP
admet-2366	544	3	chitosan	chitosan	NOUN
admet-2366	544	4	-	-	PUNCT
admet-2366	544	5	coated	coat	VERB
admet-2366	544	6	nanoliposomes	nanoliposome	NOUN
admet-2366	544	7	for	for	ADP
admet-2366	544	8	improving	improve	VERB
admet-2366	544	9	the	the	DET
admet-2366	544	10	mucoadhesive	mucoadhesive	ADJ
admet-2366	544	11	property	property	NOUN
admet-2366	544	12	of	of	ADP
admet-2366	544	13	curcumin	curcumin	NOUN
admet-2366	544	14	using	use	VERB
admet-2366	544	15	the	the	DET
admet-2366	544	16	ethanol	ethanol	NOUN
admet-2366	544	17	injection	injection	NOUN
admet-2366	544	18	method	method	NOUN
admet-2366	544	19	.	.	PUNCT
admet-2366	545	1	ournal	ournal	ADJ
admet-2366	545	2	of	of	ADP
admet-2366	545	3	agricultural	agricultural	ADJ
admet-2366	545	4	and	and	CCONJ
admet-2366	545	5	food	food	NOUN
admet-2366	545	6	chemistry	chemistry	NOUN
admet-2366	545	7	61	61	NUM
admet-2366	545	8	(	(	PUNCT
admet-2366	545	9	2013	2013	NUM
admet-2366	545	10	)	)	PUNCT
admet-2366	545	11	11119	11119	NUM
admet-2366	545	12	-	-	SYM
admet-2366	545	13	11126	11126	NUM
admet-2366	545	14	.	.	PUNCT
admet-2366	546	1	https://doi.org/10.1021/jf4035404	https://doi.org/10.1021/jf4035404	NOUN
admet-2366	546	2	.	.	PUNCT
admet-2366	547	1	[	[	X
admet-2366	547	2	39	39	NUM
admet-2366	547	3	]	]	PUNCT
admet-2366	547	4	s.	s.	PROPN
admet-2366	547	5	rohilla	rohilla	PROPN
admet-2366	547	6	,	,	PUNCT
admet-2366	547	7	r.	r.	PROPN
admet-2366	547	8	awasthi	awasthi	PROPN
admet-2366	547	9	,	,	PUNCT
admet-2366	547	10	m.	m.	NOUN
admet-2366	547	11	mehta	mehta	PROPN
admet-2366	547	12	,	,	PUNCT
admet-2366	547	13	d.k	d.k	PROPN
admet-2366	547	14	.	.	PROPN
admet-2366	547	15	chellappan	chellappan	PROPN
admet-2366	547	16	,	,	PUNCT
admet-2366	547	17	g.	g.	PROPN
admet-2366	547	18	gupta	gupta	PROPN
admet-2366	547	19	,	,	PUNCT
admet-2366	547	20	m.	m.	NOUN
admet-2366	547	21	gulati	gulati	PROPN
admet-2366	547	22	,	,	PUNCT
admet-2366	547	23	s.k	s.k	PROPN
admet-2366	547	24	.	.	PROPN
admet-2366	547	25	singh	singh	PROPN
admet-2366	547	26	,	,	PUNCT
admet-2366	547	27	k.	k.	PROPN
admet-2366	547	28	anand	anand	PROPN
admet-2366	547	29	,	,	PUNCT
admet-2366	547	30	b.g	b.g	PROPN
admet-2366	547	31	.	.	PROPN
admet-2366	547	32	oliver	oliver	PROPN
admet-2366	547	33	,	,	PUNCT
admet-2366	547	34	k.	k.	PROPN
admet-2366	547	35	dua	dua	PROPN
admet-2366	547	36	,	,	PUNCT
admet-2366	547	37	h.	h.	PROPN
admet-2366	547	38	dureja	dureja	PROPN
admet-2366	547	39	.	.	PUNCT
admet-2366	548	1	preparation	preparation	NOUN
admet-2366	548	2	and	and	CCONJ
admet-2366	548	3	evaluation	evaluation	NOUN
admet-2366	548	4	of	of	ADP
admet-2366	548	5	gefitinib	gefitinib	NOUN
admet-2366	548	6	containing	contain	VERB
admet-2366	548	7	nanoliposomal	nanoliposomal	ADJ
admet-2366	548	8	formulation	formulation	NOUN
admet-2366	548	9	for	for	ADP
admet-2366	548	10	lung	lung	NOUN
admet-2366	548	11	cancer	cancer	NOUN
admet-2366	548	12	therapy	therapy	NOUN
admet-2366	548	13	.	.	PUNCT
admet-2366	549	1	bionanoscience	bionanoscience	NOUN
admet-2366	549	2	12	12	NUM
admet-2366	549	3	(	(	PUNCT
admet-2366	549	4	2022	2022	NUM
admet-2366	549	5	)	)	PUNCT
admet-2366	549	6	241	241	NUM
admet-2366	549	7	-	-	SYM
admet-2366	549	8	255	255	NUM
admet-2366	549	9	.	.	PUNCT
admet-2366	550	1	https://doi.org/10.1007/s12668-022-00938-6	https://doi.org/10.1007/s12668-022-00938-6	X
admet-2366	550	2	.	.	PUNCT
admet-2366	551	1	[	[	X
admet-2366	551	2	40	40	NUM
admet-2366	551	3	]	]	PUNCT
admet-2366	551	4	a.	a.	NOUN
admet-2366	551	5	haeri	haeri	PROPN
admet-2366	551	6	,	,	PUNCT
admet-2366	551	7	b.	b.	PROPN
admet-2366	551	8	alinaghian	alinaghian	PROPN
admet-2366	551	9	,	,	PUNCT
admet-2366	551	10	m.	m.	NOUN
admet-2366	551	11	daeihamed	daeihamed	PROPN
admet-2366	551	12	,	,	PUNCT
admet-2366	551	13	s.	s.	PROPN
admet-2366	551	14	dadashzadeh	dadashzadeh	PROPN
admet-2366	551	15	.	.	PUNCT
admet-2366	552	1	preparation	preparation	NOUN
admet-2366	552	2	and	and	CCONJ
admet-2366	552	3	characterization	characterization	NOUN
admet-2366	552	4	of	of	ADP
admet-2366	552	5	stable	stable	ADJ
admet-2366	552	6	nano	nano	NOUN
admet-2366	552	7	-	-	PUNCT
admet-2366	552	8	liposomal	liposomal	ADJ
admet-2366	552	9	formulation	formulation	NOUN
admet-2366	552	10	of	of	ADP
admet-2366	552	11	fluoxetine	fluoxetine	NOUN
admet-2366	552	12	as	as	ADP
admet-2366	552	13	a	a	DET
admet-2366	552	14	potential	potential	ADJ
admet-2366	552	15	adjuvant	adjuvant	NOUN
admet-2366	552	16	therapy	therapy	NOUN
admet-2366	552	17	for	for	ADP
admet-2366	552	18	drug	drug	NOUN
admet-2366	552	19	-	-	PUNCT
admet-2366	552	20	resistant	resistant	ADJ
admet-2366	552	21	tumors	tumor	NOUN
admet-2366	552	22	.	.	PUNCT
admet-2366	553	1	iranian	iranian	ADJ
admet-2366	553	2	journal	journal	PROPN
admet-2366	553	3	of	of	ADP
admet-2366	553	4	pharmaceutical	pharmaceutical	ADJ
admet-2366	553	5	research	research	NOUN
admet-2366	553	6	13	13	NUM
admet-2366	553	7	(	(	PUNCT
admet-2366	553	8	2014	2014	NUM
admet-2366	553	9	)	)	PUNCT
admet-2366	553	10	3	3	NUM
admet-2366	553	11	-	-	SYM
admet-2366	553	12	14	14	NUM
admet-2366	553	13	.	.	PUNCT
admet-2366	554	1	[	[	X
admet-2366	554	2	41	41	NUM
admet-2366	554	3	]	]	X
admet-2366	554	4	s.	s.	PROPN
admet-2366	554	5	khatak	khatak	PROPN
admet-2366	554	6	,	,	PUNCT
admet-2366	554	7	m.	m.	PROPN
admet-2366	554	8	mehta	mehta	PROPN
admet-2366	554	9	,	,	PUNCT
admet-2366	554	10	r.	r.	PROPN
admet-2366	554	11	awasthi	awasthi	PROPN
admet-2366	554	12	,	,	PUNCT
admet-2366	554	13	k.r	k.r	PROPN
admet-2366	554	14	.	.	PROPN
admet-2366	554	15	paudel	paudel	PROPN
admet-2366	554	16	,	,	PUNCT
admet-2366	554	17	s.k	s.k	PROPN
admet-2366	554	18	.	.	PROPN
admet-2366	554	19	singh	singh	PROPN
admet-2366	554	20	,	,	PUNCT
admet-2366	554	21	m.	m.	NOUN
admet-2366	554	22	gulati	gulati	PROPN
admet-2366	554	23	,	,	PUNCT
admet-2366	554	24	n.g	n.g	PROPN
admet-2366	554	25	.	.	PROPN
admet-2366	554	26	hansbro	hansbro	PROPN
admet-2366	554	27	,	,	PUNCT
admet-2366	554	28	p.m.	p.m.	NOUN
admet-2366	554	29	hansbro	hansbro	PROPN
admet-2366	554	30	,	,	PUNCT
admet-2366	554	31	k.	k.	PROPN
admet-2366	554	32	dua	dua	PROPN
admet-2366	554	33	,	,	PUNCT
admet-2366	554	34	h.	h.	PROPN
admet-2366	554	35	dureja	dureja	PROPN
admet-2366	554	36	.	.	PUNCT
admet-2366	555	1	solid	solid	ADJ
admet-2366	555	2	lipid	lipid	ADJ
admet-2366	555	3	nanoparticles	nanoparticle	NOUN
admet-2366	555	4	containing	contain	VERB
admet-2366	555	5	anti	anti	ADJ
admet-2366	555	6	-	-	ADJ
admet-2366	555	7	tubercular	tubercular	ADJ
admet-2366	555	8	drugs	drug	NOUN
admet-2366	555	9	attenuate	attenuate	VERB
admet-2366	555	10	the	the	DET
admet-2366	555	11	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	ADJ
admet-2366	555	12	https://doi.org/10.1016/j.aca.2007.07.011	https://doi.org/10.1016/j.aca.2007.07.011	PROPN
admet-2366	555	13	https://doi.org/10.1016/j.bjbas.2017.06.002	https://doi.org/10.1016/j.bjbas.2017.06.002	PROPN
admet-2366	555	14	https://doi.org/10.1080/00401706.1960.10489912	https://doi.org/10.1080/00401706.1960.10489912	PUNCT
admet-2366	555	15	https://doi.org/10.1080/03601234.2012.669260	https://doi.org/10.1080/03601234.2012.669260	NOUN
admet-2366	556	1	https://doi.org/10.1186/s40659-016-0093-4	https://doi.org/10.1186/s40659-016-0093-4	NUM
admet-2366	556	2	https://doi.org/10.13040/ijpsr.0975-8232.9(12).5098-10	https://doi.org/10.13040/ijpsr.0975-8232.9(12).5098-10	DET
admet-2366	556	3	https://doi.org/10.1016/0168-3659(91)90140-9	https://doi.org/10.1016/0168-3659(91)90140-9	PROPN
admet-2366	556	4	https://doi.org/10.1016/j.colsurfb.2005.07.013	https://doi.org/10.1016/j.colsurfb.2005.07.013	PROPN
admet-2366	556	5	https://doi.org/10.3390/molecules24102023	https://doi.org/10.3390/molecules24102023	NOUN
admet-2366	556	6	https://doi.org/10.3390/md18040217	https://doi.org/10.3390/md18040217	X
admet-2366	556	7	https://doi.org/10.2174/1872211309666150629105900	https://doi.org/10.2174/1872211309666150629105900	X
admet-2366	556	8	https://doi.org/10.1016/j.jfoodeng.2010.08.022	https://doi.org/10.1016/j.jfoodeng.2010.08.022	NOUN
admet-2366	556	9	https://doi.org/10.1016/j.jare.2010.05.008	https://doi.org/10.1016/j.jare.2010.05.008	PROPN
admet-2366	556	10	https://doi.org/10.1021/jf4035404	https://doi.org/10.1021/jf4035404	NOUN
admet-2366	556	11	https://doi.org/10.1007/s12668-022-00938-6	https://doi.org/10.1007/s12668-022-00938-6	NUM
admet-2366	557	1	s.	s.	PROPN
admet-2366	557	2	rohilla	rohilla	PROPN
admet-2366	557	3	et	et	PROPN
admet-2366	557	4	al	al	PROPN
admet-2366	557	5	.	.	PROPN
admet-2366	557	6	admet	admet	PROPN
admet-2366	557	7	&	&	CCONJ
admet-2366	557	8	dmpk	dmpk	PROPN
admet-2366	557	9	12(4	12(4	PROPN
admet-2366	557	10	)	)	PUNCT
admet-2366	557	11	(	(	PUNCT
admet-2366	557	12	2024	2024	NUM
admet-2366	557	13	)	)	PUNCT
admet-2366	557	14	657	657	NUM
admet-2366	557	15	-	-	SYM
admet-2366	557	16	677	677	NUM
admet-2366	557	17	676	676	NUM
admet-2366	557	18	mycobacterium	mycobacterium	NOUN
admet-2366	557	19	marinum	marinum	ADJ
admet-2366	557	20	infection	infection	NOUN
admet-2366	557	21	.	.	PUNCT
admet-2366	558	1	tuberculosis	tuberculosis	NOUN
admet-2366	558	2	125	125	NUM
admet-2366	558	3	(	(	PUNCT
admet-2366	558	4	2020	2020	NUM
admet-2366	558	5	)	)	PUNCT
admet-2366	558	6	102008	102008	NUM
admet-2366	558	7	.	.	PUNCT
admet-2366	559	1	https://doi.org/10.1016/j.tube.2020.102008	https://doi.org/10.1016/j.tube.2020.102008	NOUN
admet-2366	559	2	.	.	PUNCT
admet-2366	560	1	[	[	X
admet-2366	560	2	42	42	NUM
admet-2366	560	3	]	]	PUNCT
admet-2366	560	4	z.	z.	PROPN
admet-2366	560	5	hadian	hadian	PROPN
admet-2366	560	6	,	,	PUNCT
admet-2366	560	7	m.a	m.a	PROPN
admet-2366	560	8	.	.	PROPN
admet-2366	560	9	sahari	sahari	PROPN
admet-2366	560	10	,	,	PUNCT
admet-2366	560	11	h.r	h.r	PROPN
admet-2366	560	12	.	.	PROPN
admet-2366	560	13	moghimi	moghimi	PROPN
admet-2366	560	14	,	,	PUNCT
admet-2366	560	15	m.	m.	NOUN
admet-2366	560	16	barzegar	barzegar	NOUN
admet-2366	560	17	.	.	PUNCT
admet-2366	561	1	formulation	formulation	NOUN
admet-2366	561	2	,	,	PUNCT
admet-2366	561	3	characterization	characterization	NOUN
admet-2366	561	4	and	and	CCONJ
admet-2366	561	5	optimization	optimization	NOUN
admet-2366	561	6	of	of	ADP
admet-2366	561	7	liposomes	liposome	NOUN
admet-2366	561	8	containing	contain	VERB
admet-2366	561	9	eicosapentaenoic	eicosapentaenoic	ADJ
admet-2366	561	10	and	and	CCONJ
admet-2366	561	11	docosahexaenoic	docosahexaenoic	ADJ
admet-2366	561	12	acids	acid	NOUN
admet-2366	561	13	;	;	PUNCT
admet-2366	561	14	a	a	DET
admet-2366	561	15	methodology	methodology	NOUN
admet-2366	561	16	approach	approach	NOUN
admet-2366	561	17	.	.	PUNCT
admet-2366	562	1	iranian	iranian	ADJ
admet-2366	562	2	journal	journal	PROPN
admet-2366	562	3	of	of	ADP
admet-2366	562	4	pharmaceutical	pharmaceutical	ADJ
admet-2366	562	5	research	research	NOUN
admet-2366	562	6	13	13	NUM
admet-2366	562	7	(	(	PUNCT
admet-2366	562	8	2014	2014	NUM
admet-2366	562	9	)	)	PUNCT
admet-2366	562	10	393	393	NUM
admet-2366	562	11	-	-	SYM
admet-2366	562	12	404	404	NUM
admet-2366	562	13	.	.	PUNCT
admet-2366	563	1	[	[	X
admet-2366	563	2	43	43	NUM
admet-2366	563	3	]	]	X
admet-2366	563	4	y.	y.	PROPN
admet-2366	563	5	chan	chan	PROPN
admet-2366	563	6	,	,	PUNCT
admet-2366	563	7	s.w	s.w	PROPN
admet-2366	563	8	.	.	PROPN
admet-2366	563	9	ng	ng	PROPN
admet-2366	563	10	,	,	PUNCT
admet-2366	563	11	d.k	d.k	PROPN
admet-2366	563	12	.	.	PROPN
admet-2366	563	13	chellappan	chellappan	PROPN
admet-2366	563	14	,	,	PUNCT
admet-2366	563	15	t.	t.	PROPN
admet-2366	563	16	madheswaran	madheswaran	PROPN
admet-2366	563	17	,	,	PUNCT
admet-2366	563	18	f.	f.	PROPN
admet-2366	563	19	zeeshan	zeeshan	PROPN
admet-2366	563	20	,	,	PUNCT
admet-2366	563	21	p.	p.	PROPN
admet-2366	563	22	kumar	kumar	PROPN
admet-2366	563	23	,	,	PUNCT
admet-2366	563	24	v.	v.	PROPN
admet-2366	563	25	pillay	pillay	PROPN
admet-2366	563	26	,	,	PUNCT
admet-2366	563	27	g.	g.	PROPN
admet-2366	563	28	gupta	gupta	PROPN
admet-2366	563	29	,	,	PUNCT
admet-2366	563	30	r.	r.	PROPN
admet-2366	563	31	wadhwa	wadhwa	PROPN
admet-2366	563	32	,	,	PUNCT
admet-2366	563	33	m.	m.	NOUN
admet-2366	563	34	mehta	mehta	PROPN
admet-2366	563	35	,	,	PUNCT
admet-2366	563	36	p.	p.	NOUN
admet-2366	563	37	wark	wark	PROPN
admet-2366	563	38	.	.	PUNCT
admet-2366	564	1	celastrol	celastrol	NOUN
admet-2366	564	2	-	-	PUNCT
admet-2366	564	3	loaded	load	VERB
admet-2366	564	4	liquid	liquid	ADJ
admet-2366	564	5	crystalline	crystalline	NOUN
admet-2366	564	6	nanoparticles	nanoparticle	NOUN
admet-2366	564	7	as	as	ADP
admet-2366	564	8	an	an	DET
admet-2366	564	9	antiinflammatory	antiinflammatory	NOUN
admet-2366	564	10	intervention	intervention	NOUN
admet-2366	564	11	for	for	ADP
admet-2366	564	12	the	the	DET
admet-2366	564	13	treatment	treatment	NOUN
admet-2366	564	14	of	of	ADP
admet-2366	564	15	asthma	asthma	NOUN
admet-2366	564	16	.	.	PUNCT
admet-2366	565	1	international	international	ADJ
admet-2366	565	2	journal	journal	NOUN
admet-2366	565	3	of	of	ADP
admet-2366	565	4	polymeric	polymeric	ADJ
admet-2366	565	5	materials	material	NOUN
admet-2366	565	6	and	and	CCONJ
admet-2366	565	7	polymeric	polymeric	ADJ
admet-2366	565	8	biomaterials	biomaterial	NOUN
admet-2366	565	9	70	70	NUM
admet-2366	565	10	(	(	PUNCT
admet-2366	565	11	2021	2021	NUM
admet-2366	565	12	)	)	PUNCT
admet-2366	565	13	754	754	NUM
admet-2366	565	14	-	-	SYM
admet-2366	565	15	763	763	NUM
admet-2366	565	16	.	.	PUNCT
admet-2366	566	1	https://doi.org/10.1080/00914037.2020.1765350	https://doi.org/10.1080/00914037.2020.1765350	PROPN
admet-2366	566	2	.	.	PUNCT
admet-2366	567	1	[	[	X
admet-2366	567	2	44	44	NUM
admet-2366	567	3	]	]	PUNCT
admet-2366	567	4	m.	m.	NOUN
admet-2366	567	5	mehta	mehta	PROPN
admet-2366	567	6	,	,	PUNCT
admet-2366	567	7	h.	h.	PROPN
admet-2366	567	8	dureja	dureja	PROPN
admet-2366	567	9	,	,	PUNCT
admet-2366	567	10	m.	m.	NOUN
admet-2366	567	11	garg	garg	PROPN
admet-2366	567	12	.	.	PUNCT
admet-2366	568	1	development	development	NOUN
admet-2366	568	2	and	and	CCONJ
admet-2366	568	3	optimization	optimization	NOUN
admet-2366	568	4	of	of	ADP
admet-2366	568	5	boswellic	boswellic	ADJ
admet-2366	568	6	acid	acid	NOUN
admet-2366	568	7	-	-	PUNCT
admet-2366	568	8	loaded	load	VERB
admet-2366	568	9	proniosomal	proniosomal	ADJ
admet-2366	568	10	gel	gel	NOUN
admet-2366	568	11	.	.	PUNCT
admet-2366	569	1	drug	drug	NOUN
admet-2366	569	2	delivery	delivery	NOUN
admet-2366	569	3	23	23	NUM
admet-2366	569	4	(	(	PUNCT
admet-2366	569	5	2016	2016	NUM
admet-2366	569	6	)	)	PUNCT
admet-2366	569	7	3072	3072	NUM
admet-2366	569	8	-	-	SYM
admet-2366	569	9	3081	3081	NUM
admet-2366	569	10	.	.	PUNCT
admet-2366	570	1	https://doi.org/10.3109/10717544.2016.1149744	https://doi.org/10.3109/10717544.2016.1149744	PROPN
admet-2366	570	2	.	.	PUNCT
admet-2366	571	1	[	[	X
admet-2366	571	2	45	45	NUM
admet-2366	571	3	]	]	PUNCT
admet-2366	571	4	a.	a.	NOUN
admet-2366	571	5	grover	grover	PROPN
admet-2366	571	6	,	,	PUNCT
admet-2366	571	7	l.z	l.z	PROPN
admet-2366	571	8	.	.	PROPN
admet-2366	571	9	benet	benet	PROPN
admet-2366	571	10	.	.	PUNCT
admet-2366	572	1	intermittent	intermittent	ADJ
admet-2366	572	2	drug	drug	NOUN
admet-2366	572	3	dosing	dose	VERB
admet-2366	572	4	intervals	interval	NOUN
admet-2366	572	5	guided	guide	VERB
admet-2366	572	6	by	by	ADP
admet-2366	572	7	the	the	DET
admet-2366	572	8	operational	operational	ADJ
admet-2366	572	9	multiple	multiple	ADJ
admet-2366	572	10	dosing	dose	VERB
admet-2366	572	11	half	half	NOUN
admet-2366	572	12	lives	life	NOUN
admet-2366	572	13	for	for	ADP
admet-2366	572	14	predictable	predictable	ADJ
admet-2366	572	15	plasma	plasma	NOUN
admet-2366	572	16	accumulation	accumulation	NOUN
admet-2366	572	17	and	and	CCONJ
admet-2366	572	18	fluctuation	fluctuation	NOUN
admet-2366	572	19	.	.	PUNCT
admet-2366	573	1	journal	journal	NOUN
admet-2366	573	2	of	of	ADP
admet-2366	573	3	pharmacokinetics	pharmacokinetic	NOUN
admet-2366	573	4	and	and	CCONJ
admet-2366	573	5	pharmacodynamics	pharmacodynamic	NOUN
admet-2366	573	6	38	38	NUM
admet-2366	573	7	(	(	PUNCT
admet-2366	573	8	2011	2011	NUM
admet-2366	573	9	)	)	PUNCT
admet-2366	573	10	369	369	NUM
admet-2366	573	11	-	-	SYM
admet-2366	573	12	383	383	NUM
admet-2366	573	13	.	.	PUNCT
admet-2366	574	1	https://doi.org/10.1007/s10928-011-9198-0	https://doi.org/10.1007/s10928-011-9198-0	NUM
admet-2366	574	2	.	.	PUNCT
admet-2366	575	1	[	[	X
admet-2366	575	2	46	46	NUM
admet-2366	575	3	]	]	X
admet-2366	575	4	indian	indian	ADJ
admet-2366	575	5	pharmacopoeia	pharmacopoeia	NOUN
admet-2366	575	6	.	.	PUNCT
admet-2366	576	1	government	government	NOUN
admet-2366	576	2	of	of	ADP
admet-2366	576	3	india	india	PROPN
admet-2366	576	4	,	,	PUNCT
admet-2366	576	5	ministry	ministry	PROPN
admet-2366	576	6	of	of	ADP
admet-2366	576	7	health	health	PROPN
admet-2366	576	8	and	and	CCONJ
admet-2366	576	9	family	family	NOUN
admet-2366	576	10	welfare	welfare	NOUN
admet-2366	576	11	.	.	PUNCT
admet-2366	577	1	2	2	NUM
admet-2366	577	2	(	(	PUNCT
admet-2366	577	3	1996	1996	NUM
admet-2366	577	4	)	)	PUNCT
admet-2366	577	5	448	448	NUM
admet-2366	577	6	.	.	PUNCT
admet-2366	578	1	[	[	X
admet-2366	578	2	47	47	NUM
admet-2366	578	3	]	]	X
admet-2366	578	4	x.l	x.l	PROPN
admet-2366	578	5	.	.	PUNCT
admet-2366	578	6	ni	ni	PROPN
admet-2366	578	7	,	,	PUNCT
admet-2366	578	8	l.x	l.x	PROPN
admet-2366	578	9	.	.	PUNCT
admet-2366	578	10	chen	chen	PROPN
admet-2366	578	11	,	,	PUNCT
admet-2366	578	12	h.	h.	PROPN
admet-2366	578	13	zhang	zhang	PROPN
admet-2366	578	14	,	,	PUNCT
admet-2366	578	15	b.	b.	PROPN
admet-2366	578	16	yang	yang	PROPN
admet-2366	578	17	,	,	PUNCT
admet-2366	578	18	s.	s.	PROPN
admet-2366	578	19	xu	xu	PROPN
admet-2366	578	20	,	,	PUNCT
admet-2366	578	21	m.	m.	PROPN
admet-2366	578	22	wu	wu	PROPN
admet-2366	578	23	.	.	PUNCT
admet-2366	579	1	in	in	ADP
admet-2366	579	2	vitro	vitro	X
admet-2366	579	3	and	and	CCONJ
admet-2366	579	4	in	in	ADP
admet-2366	579	5	vivo	vivo	ADJ
admet-2366	579	6	antitumor	antitumor	PROPN
admet-2366	579	7	effect	effect	NOUN
admet-2366	579	8	of	of	ADP
admet-2366	579	9	gefitinib	gefitinib	NOUN
admet-2366	579	10	nanoparticles	nanoparticle	NOUN
admet-2366	579	11	on	on	ADP
admet-2366	579	12	human	human	ADJ
admet-2366	579	13	lung	lung	NOUN
admet-2366	579	14	cancer	cancer	NOUN
admet-2366	579	15	.	.	PUNCT
admet-2366	580	1	drug	drug	NOUN
admet-2366	580	2	delivery	delivery	NOUN
admet-2366	580	3	24	24	NUM
admet-2366	580	4	(	(	PUNCT
admet-2366	580	5	2017	2017	NUM
admet-2366	580	6	)	)	PUNCT
admet-2366	580	7	1501	1501	NUM
admet-2366	580	8	-	-	SYM
admet-2366	580	9	1512	1512	NUM
admet-2366	580	10	.	.	PUNCT
admet-2366	581	1	https://doi.org/10.1080/10717544.2017.1384862	https://doi.org/10.1080/10717544.2017.1384862	NOUN
admet-2366	581	2	.	.	PUNCT
admet-2366	582	1	[	[	X
admet-2366	582	2	48	48	NUM
admet-2366	582	3	]	]	PUNCT
admet-2366	582	4	r.	r.	NOUN
admet-2366	582	5	mirzayans	mirzayans	PROPN
admet-2366	582	6	,	,	PUNCT
admet-2366	582	7	b.	b.	PROPN
admet-2366	582	8	andrais	andrais	PROPN
admet-2366	582	9	,	,	PUNCT
admet-2366	582	10	a.	a.	PROPN
admet-2366	582	11	scott	scott	PROPN
admet-2366	582	12	,	,	PUNCT
admet-2366	582	13	a.	a.	NOUN
admet-2366	582	14	tessier	tessier	PROPN
admet-2366	582	15	,	,	PUNCT
admet-2366	582	16	d.	d.	PROPN
admet-2366	582	17	murray	murray	PROPN
admet-2366	582	18	.	.	PUNCT
admet-2366	583	1	a	a	DET
admet-2366	583	2	sensitive	sensitive	ADJ
admet-2366	583	3	assay	assay	NOUN
admet-2366	583	4	for	for	ADP
admet-2366	583	5	the	the	DET
admet-2366	583	6	evaluation	evaluation	NOUN
admet-2366	583	7	of	of	ADP
admet-2366	583	8	cytotoxicity	cytotoxicity	NOUN
admet-2366	583	9	and	and	CCONJ
admet-2366	583	10	its	its	PRON
admet-2366	583	11	pharmacologic	pharmacologic	ADJ
admet-2366	583	12	modulation	modulation	NOUN
admet-2366	583	13	in	in	ADP
admet-2366	583	14	human	human	ADJ
admet-2366	583	15	solid	solid	ADJ
admet-2366	583	16	tumor	tumor	NOUN
admet-2366	583	17	-	-	PUNCT
admet-2366	583	18	derived	derive	VERB
admet-2366	583	19	cell	cell	NOUN
admet-2366	583	20	lines	line	NOUN
admet-2366	583	21	exposed	expose	VERB
admet-2366	583	22	to	to	ADP
admet-2366	583	23	cancer	cancer	NOUN
admet-2366	583	24	-	-	PUNCT
admet-2366	583	25	therapeutic	therapeutic	ADJ
admet-2366	583	26	agents	agent	NOUN
admet-2366	583	27	.	.	PUNCT
admet-2366	584	1	journal	journal	NOUN
admet-2366	584	2	of	of	ADP
admet-2366	584	3	pharmacy	pharmacy	PROPN
admet-2366	584	4	&	&	CCONJ
admet-2366	584	5	pharmaceutical	pharmaceutical	NOUN
admet-2366	584	6	sciences	science	NOUN
admet-2366	584	7	10	10	NUM
admet-2366	584	8	(	(	PUNCT
admet-2366	584	9	2007	2007	NUM
admet-2366	584	10	)	)	PUNCT
admet-2366	584	11	298s-311s	298s-311s	NOUN
admet-2366	584	12	.	.	PUNCT
admet-2366	585	1	[	[	X
admet-2366	585	2	49	49	NUM
admet-2366	585	3	]	]	PUNCT
admet-2366	585	4	p.	p.	NOUN
admet-2366	585	5	skupin	skupin	PROPN
admet-2366	585	6	-	-	PUNCT
admet-2366	585	7	mrugalska	mrugalska	PROPN
admet-2366	585	8	,	,	PUNCT
admet-2366	585	9	t.j	t.j	PROPN
admet-2366	585	10	.	.	PROPN
admet-2366	585	11	minko	minko	PROPN
admet-2366	585	12	.	.	PUNCT
admet-2366	586	1	development	development	NOUN
admet-2366	586	2	of	of	ADP
admet-2366	586	3	liposomal	liposomal	ADJ
admet-2366	586	4	vesicles	vesicle	NOUN
admet-2366	586	5	for	for	ADP
admet-2366	586	6	osimertinib	osimertinib	NOUN
admet-2366	586	7	delivery	delivery	NOUN
admet-2366	586	8	to	to	PART
admet-2366	586	9	egfr	egfr	VERB
admet-2366	586	10	mutation	mutation	NOUN
admet-2366	586	11	-	-	PUNCT
admet-2366	586	12	positive	positive	ADJ
admet-2366	586	13	lung	lung	NOUN
admet-2366	586	14	cancer	cancer	NOUN
admet-2366	586	15	cells	cell	NOUN
admet-2366	586	16	.	.	PUNCT
admet-2366	587	1	pharmaceutics	pharmaceutic	NOUN
admet-2366	587	2	12	12	NUM
admet-2366	587	3	(	(	PUNCT
admet-2366	587	4	2020	2020	NUM
admet-2366	587	5	)	)	PUNCT
admet-2366	587	6	939	939	NUM
admet-2366	587	7	.	.	PUNCT
admet-2366	588	1	https://doi.org/10.3390/pharmaceutics12100939	https://doi.org/10.3390/pharmaceutics12100939	NOUN
admet-2366	588	2	.	.	PUNCT
admet-2366	589	1	[	[	X
admet-2366	589	2	50	50	NUM
admet-2366	589	3	]	]	X
admet-2366	589	4	r.	r.	PROPN
admet-2366	589	5	talens	talens	PROPN
admet-2366	589	6	-	-	PUNCT
admet-2366	589	7	visconti	visconti	PROPN
admet-2366	589	8	,	,	PUNCT
admet-2366	589	9	o.	o.	PROPN
admet-2366	589	10	diez	diez	PROPN
admet-2366	589	11	-	-	PUNCT
admet-2366	589	12	sales	sale	NOUN
admet-2366	589	13	,	,	PUNCT
admet-2366	589	14	j.v	j.v	PROPN
admet-2366	589	15	.	.	PROPN
admet-2366	589	16	de	de	PROPN
admet-2366	589	17	julian	julian	PROPN
admet-2366	589	18	-	-	PUNCT
admet-2366	589	19	ortiz	ortiz	PROPN
admet-2366	589	20	,	,	PUNCT
admet-2366	589	21	a.	a.	NOUN
admet-2366	589	22	nacher	nacher	NOUN
admet-2366	589	23	.	.	PUNCT
admet-2366	590	1	nanoliposomes	nanoliposome	NOUN
admet-2366	590	2	in	in	ADP
admet-2366	590	3	cancer	cancer	NOUN
admet-2366	590	4	therapy	therapy	NOUN
admet-2366	590	5	:	:	PUNCT
admet-2366	590	6	marketed	market	VERB
admet-2366	590	7	products	product	NOUN
admet-2366	590	8	and	and	CCONJ
admet-2366	590	9	current	current	ADJ
admet-2366	590	10	clinical	clinical	ADJ
admet-2366	590	11	trials	trial	NOUN
admet-2366	590	12	.	.	PUNCT
admet-2366	591	1	international	international	ADJ
admet-2366	591	2	journal	journal	NOUN
admet-2366	591	3	of	of	ADP
admet-2366	591	4	molecular	molecular	ADJ
admet-2366	591	5	sciences	science	NOUN
admet-2366	591	6	23	23	NUM
admet-2366	591	7	(	(	PUNCT
admet-2366	591	8	2022	2022	NUM
admet-2366	591	9	)	)	PUNCT
admet-2366	591	10	4249	4249	NUM
admet-2366	591	11	.	.	PUNCT
admet-2366	592	1	https://doi.org/10.3390/ijms23084249	https://doi.org/10.3390/ijms23084249	PROPN
admet-2366	592	2	.	.	PUNCT
admet-2366	593	1	[	[	X
admet-2366	593	2	51	51	NUM
admet-2366	593	3	]	]	PUNCT
admet-2366	593	4	m.	m.	NOUN
admet-2366	593	5	chiani	chiani	PROPN
admet-2366	593	6	,	,	PUNCT
admet-2366	593	7	d.	d.	PROPN
admet-2366	593	8	norouzian	norouzian	PROPN
admet-2366	593	9	,	,	PUNCT
admet-2366	593	10	m.a	m.a	PROPN
admet-2366	593	11	.	.	PROPN
admet-2366	593	12	shokrgozar	shokrgozar	PROPN
admet-2366	593	13	,	,	PUNCT
admet-2366	593	14	k.	k.	PROPN
admet-2366	593	15	azadmanesh	azadmanesh	PROPN
admet-2366	593	16	,	,	PUNCT
admet-2366	593	17	a.	a.	NOUN
admet-2366	593	18	najmafshar	najmafshar	PROPN
admet-2366	593	19	,	,	PUNCT
admet-2366	593	20	m.r	m.r	PROPN
admet-2366	593	21	.	.	PROPN
admet-2366	593	22	mehrabi	mehrabi	PROPN
admet-2366	593	23	,	,	PUNCT
admet-2366	593	24	a.	a.	NOUN
admet-2366	593	25	akbarzadeh	akbarzadeh	PROPN
admet-2366	593	26	.	.	PUNCT
admet-2366	594	1	folic	folic	ADJ
admet-2366	594	2	acid	acid	NOUN
admet-2366	594	3	conjugated	conjugate	VERB
admet-2366	594	4	nanoliposomes	nanoliposome	NOUN
admet-2366	594	5	as	as	ADP
admet-2366	594	6	promising	promise	VERB
admet-2366	594	7	carriers	carrier	NOUN
admet-2366	594	8	for	for	ADP
admet-2366	594	9	targeted	target	VERB
admet-2366	594	10	delivery	delivery	NOUN
admet-2366	594	11	of	of	ADP
admet-2366	594	12	bleomycin	bleomycin	PROPN
admet-2366	594	13	.	.	PUNCT
admet-2366	595	1	artificial	artificial	ADJ
admet-2366	595	2	cells	cell	NOUN
admet-2366	595	3	nanomedicine	nanomedicine	NOUN
admet-2366	595	4	and	and	CCONJ
admet-2366	595	5	biotechnology	biotechnology	NOUN
admet-2366	595	6	46	46	NUM
admet-2366	595	7	(	(	PUNCT
admet-2366	595	8	2018	2018	NUM
admet-2366	595	9	)	)	PUNCT
admet-2366	595	10	757	757	PROPN
admet-2366	595	11	-	-	SYM
admet-2366	595	12	763	763	NUM
admet-2366	595	13	.	.	PUNCT
admet-2366	596	1	https://doi.org/10.1080/21691401.2017.1337029	https://doi.org/10.1080/21691401.2017.1337029	PROPN
admet-2366	596	2	.	.	PUNCT
admet-2366	597	1	[	[	X
admet-2366	597	2	52	52	NUM
admet-2366	597	3	]	]	PUNCT
admet-2366	597	4	m.	m.	NOUN
admet-2366	597	5	mozafari	mozafari	NOUN
admet-2366	597	6	.	.	PUNCT
admet-2366	598	1	in	in	ADP
admet-2366	598	2	:	:	PUNCT
admet-2366	598	3	liposomes	liposome	NOUN
admet-2366	598	4	.	.	PUNCT
admet-2366	599	1	methods	method	NOUN
admet-2366	599	2	in	in	ADP
admet-2366	599	3	molecular	molecular	ADJ
admet-2366	599	4	biology	biology	NOUN
admet-2366	599	5	,	,	PUNCT
admet-2366	599	6	v.	v.	CCONJ
admet-2366	599	7	weissig	weissig	X
admet-2366	599	8	,	,	PUNCT
admet-2366	599	9	(	(	PUNCT
admet-2366	599	10	ed	ed	NOUN
admet-2366	599	11	)	)	PUNCT
admet-2366	599	12	.	.	PUNCT
admet-2366	599	13	,	,	PUNCT
admet-2366	599	14	humana	humana	PROPN
admet-2366	599	15	press	press	PROPN
admet-2366	599	16	,	,	PUNCT
admet-2366	599	17	new	new	PROPN
admet-2366	599	18	jersey	jersey	PROPN
admet-2366	599	19	,	,	PUNCT
admet-2366	599	20	united	united	PROPN
admet-2366	599	21	states	states	PROPN
admet-2366	599	22	,	,	PUNCT
admet-2366	599	23	2010	2010	NUM
admet-2366	599	24	p.	p.	NOUN
admet-2366	599	25	29	29	NUM
admet-2366	599	26	-	-	SYM
admet-2366	599	27	50	50	NUM
admet-2366	599	28	.	.	PUNCT
admet-2366	600	1	https://doi.org/10.1007/978-1-60327-360-2_2	https://doi.org/10.1007/978-1-60327-360-2_2	X
admet-2366	600	2	.	.	PUNCT
admet-2366	601	1	[	[	X
admet-2366	601	2	53	53	NUM
admet-2366	601	3	]	]	X
admet-2366	601	4	y.	y.	PROPN
admet-2366	601	5	chan	chan	PROPN
admet-2366	601	6	,	,	PUNCT
admet-2366	601	7	s.w	s.w	PROPN
admet-2366	601	8	.	.	PROPN
admet-2366	601	9	ng	ng	PROPN
admet-2366	601	10	,	,	PUNCT
admet-2366	601	11	d.k	d.k	PROPN
admet-2366	601	12	.	.	PROPN
admet-2366	601	13	chellappan	chellappan	PROPN
admet-2366	601	14	,	,	PUNCT
admet-2366	601	15	t.	t.	PROPN
admet-2366	601	16	madheswaran	madheswaran	PROPN
admet-2366	601	17	,	,	PUNCT
admet-2366	601	18	f.	f.	PROPN
admet-2366	601	19	zeeshan	zeeshan	PROPN
admet-2366	601	20	,	,	PUNCT
admet-2366	601	21	p.	p.	PROPN
admet-2366	601	22	kumar	kumar	PROPN
admet-2366	601	23	,	,	PUNCT
admet-2366	601	24	v.	v.	PROPN
admet-2366	601	25	pillay	pillay	PROPN
admet-2366	601	26	,	,	PUNCT
admet-2366	601	27	g.	g.	PROPN
admet-2366	601	28	gupta	gupta	PROPN
admet-2366	601	29	,	,	PUNCT
admet-2366	601	30	r.	r.	PROPN
admet-2366	601	31	wadhwa	wadhwa	PROPN
admet-2366	601	32	,	,	PUNCT
admet-2366	601	33	m.	m.	NOUN
admet-2366	601	34	mehta	mehta	PROPN
admet-2366	601	35	,	,	PUNCT
admet-2366	601	36	p.	p.	NOUN
admet-2366	601	37	wark	wark	PROPN
admet-2366	601	38	.	.	PUNCT
admet-2366	602	1	celastrol	celastrol	NOUN
admet-2366	602	2	-	-	PUNCT
admet-2366	602	3	loaded	load	VERB
admet-2366	602	4	liquid	liquid	ADJ
admet-2366	602	5	crystalline	crystalline	NOUN
admet-2366	602	6	nanoparticles	nanoparticle	NOUN
admet-2366	602	7	as	as	ADP
admet-2366	602	8	an	an	DET
admet-2366	602	9	antiinflammatory	antiinflammatory	NOUN
admet-2366	602	10	intervention	intervention	NOUN
admet-2366	602	11	for	for	ADP
admet-2366	602	12	the	the	DET
admet-2366	602	13	treatment	treatment	NOUN
admet-2366	602	14	of	of	ADP
admet-2366	602	15	asthma	asthma	NOUN
admet-2366	602	16	.	.	PUNCT
admet-2366	603	1	international	international	ADJ
admet-2366	603	2	journal	journal	NOUN
admet-2366	603	3	of	of	ADP
admet-2366	603	4	polymeric	polymeric	ADJ
admet-2366	603	5	materials	material	NOUN
admet-2366	603	6	and	and	CCONJ
admet-2366	603	7	polymeric	polymeric	ADJ
admet-2366	603	8	biomaterials	biomaterial	NOUN
admet-2366	603	9	70	70	NUM
admet-2366	603	10	(	(	PUNCT
admet-2366	603	11	2021	2021	NUM
admet-2366	603	12	)	)	PUNCT
admet-2366	603	13	754	754	NUM
admet-2366	603	14	-	-	SYM
admet-2366	603	15	763	763	NUM
admet-2366	603	16	.	.	PUNCT
admet-2366	604	1	https://doi.org/10.1080/00914037.2020.1765350	https://doi.org/10.1080/00914037.2020.1765350	PROPN
admet-2366	604	2	.	.	PUNCT
admet-2366	605	1	[	[	X
admet-2366	605	2	54	54	NUM
admet-2366	605	3	]	]	PUNCT
admet-2366	605	4	l.	l.	PROPN
admet-2366	605	5	cheng	cheng	PROPN
admet-2366	605	6	,	,	PUNCT
admet-2366	605	7	c.	c.	PROPN
admet-2366	605	8	jin	jin	PROPN
admet-2366	605	9	,	,	PUNCT
admet-2366	605	10	w.	w.	PROPN
admet-2366	605	11	lv	lv	PROPN
admet-2366	605	12	,	,	PUNCT
admet-2366	605	13	q.	q.	PROPN
admet-2366	605	14	ding	ding	PROPN
admet-2366	605	15	,	,	PUNCT
admet-2366	605	16	x.	x.	PROPN
admet-2366	605	17	han	han	PROPN
admet-2366	605	18	.	.	PUNCT
admet-2366	605	19	developing	develop	VERB
admet-2366	605	20	a	a	DET
admet-2366	605	21	highly	highly	ADV
admet-2366	605	22	stable	stable	ADJ
admet-2366	605	23	plga	plga	NOUN
admet-2366	605	24	-	-	PUNCT
admet-2366	605	25	mpeg	mpeg	NOUN
admet-2366	605	26	nanoparticle	nanoparticle	NOUN
admet-2366	605	27	loaded	load	VERB
admet-2366	605	28	with	with	ADP
admet-2366	605	29	cisplatin	cisplatin	NOUN
admet-2366	605	30	for	for	ADP
admet-2366	605	31	chemotherapy	chemotherapy	NOUN
admet-2366	605	32	of	of	ADP
admet-2366	605	33	ovarian	ovarian	ADJ
admet-2366	605	34	cancer	cancer	NOUN
admet-2366	605	35	.	.	PUNCT
admet-2366	606	1	plos	plos	PROPN
admet-2366	606	2	one	one	NUM
admet-2366	606	3	6	6	NUM
admet-2366	606	4	(	(	PUNCT
admet-2366	606	5	2011	2011	NUM
admet-2366	606	6	)	)	PUNCT
admet-2366	606	7	e25433	e25433	NOUN
admet-2366	606	8	.	.	PUNCT
admet-2366	607	1	https://doi.org/10.1371/journal.pone.0025433	https://doi.org/10.1371/journal.pone.0025433	NOUN
admet-2366	607	2	.	.	PUNCT
admet-2366	608	1	[	[	X
admet-2366	608	2	55	55	NUM
admet-2366	608	3	]	]	PUNCT
admet-2366	608	4	x.	x.	NOUN
admet-2366	608	5	zhou	zhou	PROPN
admet-2366	608	6	,	,	PUNCT
admet-2366	608	7	b.	b.	PROPN
admet-2366	608	8	yung	yung	PROPN
admet-2366	608	9	,	,	PUNCT
admet-2366	608	10	y.	y.	PROPN
admet-2366	608	11	huang	huang	PROPN
admet-2366	608	12	,	,	PUNCT
admet-2366	608	13	h.	h.	PROPN
admet-2366	608	14	li	li	PROPN
admet-2366	608	15	,	,	PUNCT
admet-2366	608	16	x.	x.	PROPN
admet-2366	608	17	hu	hu	PROPN
admet-2366	608	18	,	,	PUNCT
admet-2366	608	19	g.	g.	PROPN
admet-2366	608	20	xiang	xiang	PROPN
admet-2366	608	21	,	,	PUNCT
admet-2366	608	22	r.j	r.j	PROPN
admet-2366	608	23	.	.	PROPN
admet-2366	608	24	lee	lee	PROPN
admet-2366	608	25	.	.	PROPN
admet-2366	608	26	novel	novel	PROPN
admet-2366	608	27	liposomal	liposomal	ADJ
admet-2366	608	28	gefitinib	gefitinib	NOUN
admet-2366	608	29	(	(	PUNCT
admet-2366	608	30	l	l	NOUN
admet-2366	608	31	-	-	ADJ
admet-2366	608	32	gef	gef	ADJ
admet-2366	608	33	)	)	PUNCT
admet-2366	608	34	formulations	formulation	NOUN
admet-2366	608	35	.	.	PUNCT
admet-2366	609	1	anticancer	anticancer	NOUN
admet-2366	609	2	research	research	NOUN
admet-2366	609	3	32	32	NUM
admet-2366	609	4	(	(	PUNCT
admet-2366	609	5	2012	2012	NUM
admet-2366	609	6	)	)	PUNCT
admet-2366	609	7	2919	2919	NUM
admet-2366	609	8	-	-	SYM
admet-2366	609	9	2923	2923	NUM
admet-2366	609	10	.	.	PUNCT
admet-2366	610	1	[	[	X
admet-2366	610	2	56	56	NUM
admet-2366	610	3	]	]	X
admet-2366	610	4	h.k	h.k	PROPN
admet-2366	610	5	.	.	PROPN
admet-2366	610	6	ha	ha	INTJ
admet-2366	610	7	,	,	PUNCT
admet-2366	610	8	j.w	j.w	PROPN
admet-2366	610	9	.	.	PUNCT
admet-2366	610	10	kim	kim	PROPN
admet-2366	610	11	,	,	PUNCT
admet-2366	610	12	m.r	m.r	PROPN
admet-2366	610	13	.	.	PROPN
admet-2366	610	14	lee	lee	PROPN
admet-2366	610	15	,	,	PUNCT
admet-2366	610	16	w.	w.	PROPN
admet-2366	610	17	jun	jun	PROPN
admet-2366	610	18	,	,	PUNCT
admet-2366	610	19	w.j	w.j	PROPN
admet-2366	610	20	.	.	PROPN
admet-2366	610	21	lee	lee	PROPN
admet-2366	610	22	.	.	PUNCT
admet-2366	611	1	cellular	cellular	ADJ
admet-2366	611	2	uptake	uptake	NOUN
admet-2366	611	3	and	and	CCONJ
admet-2366	611	4	cytotoxicity	cytotoxicity	NOUN
admet-2366	611	5	of	of	ADP
admet-2366	611	6	β	β	NOUN
admet-2366	611	7	-	-	PUNCT
admet-2366	611	8	lactoglobulin	lactoglobulin	NOUN
admet-2366	611	9	nanoparticles	nanoparticle	NOUN
admet-2366	611	10	:	:	PUNCT
admet-2366	611	11	the	the	DET
admet-2366	611	12	effects	effect	NOUN
admet-2366	611	13	of	of	ADP
admet-2366	611	14	particle	particle	NOUN
admet-2366	611	15	size	size	NOUN
admet-2366	611	16	and	and	CCONJ
admet-2366	611	17	surface	surface	NOUN
admet-2366	611	18	charge	charge	NOUN
admet-2366	611	19	.	.	PUNCT
admet-2366	612	1	asian	asian	ADJ
admet-2366	612	2	-	-	PUNCT
admet-2366	612	3	australasian	australasian	ADJ
admet-2366	612	4	journal	journal	NOUN
admet-2366	612	5	of	of	ADP
admet-2366	612	6	animal	animal	NOUN
admet-2366	612	7	sciences	science	NOUN
admet-2366	612	8	28	28	NUM
admet-2366	612	9	(	(	PUNCT
admet-2366	612	10	2015	2015	NUM
admet-2366	612	11	)	)	PUNCT
admet-2366	612	12	420	420	NUM
admet-2366	612	13	-	-	SYM
admet-2366	612	14	427	427	NUM
admet-2366	612	15	.	.	PUNCT
admet-2366	613	1	https://doi.org/10.5713/ajas.14.0761	https://doi.org/10.5713/ajas.14.0761	VERB
admet-2366	613	2	.	.	PUNCT
admet-2366	614	1	[	[	X
admet-2366	614	2	57	57	NUM
admet-2366	614	3	]	]	PUNCT
admet-2366	614	4	c.	c.	NOUN
admet-2366	614	5	he	he	PRON
admet-2366	614	6	,	,	PUNCT
admet-2366	614	7	y.	y.	PROPN
admet-2366	614	8	hu	hu	PROPN
admet-2366	614	9	,	,	PUNCT
admet-2366	614	10	l.	l.	PROPN
admet-2366	614	11	yin	yin	PROPN
admet-2366	614	12	,	,	PUNCT
admet-2366	614	13	c.	c.	PROPN
admet-2366	614	14	tang	tang	PROPN
admet-2366	614	15	,	,	PUNCT
admet-2366	614	16	c.	c.	PROPN
admet-2366	614	17	yin	yin	PROPN
admet-2366	614	18	.	.	PUNCT
admet-2366	615	1	effects	effect	NOUN
admet-2366	615	2	of	of	ADP
admet-2366	615	3	particle	particle	NOUN
admet-2366	615	4	size	size	NOUN
admet-2366	615	5	and	and	CCONJ
admet-2366	615	6	surface	surface	NOUN
admet-2366	615	7	charge	charge	NOUN
admet-2366	615	8	on	on	ADP
admet-2366	615	9	cellular	cellular	ADJ
admet-2366	615	10	uptake	uptake	NOUN
admet-2366	615	11	and	and	CCONJ
admet-2366	615	12	biodistribution	biodistribution	NOUN
admet-2366	615	13	of	of	ADP
admet-2366	615	14	polymeric	polymeric	ADJ
admet-2366	615	15	nanoparticles	nanoparticle	NOUN
admet-2366	615	16	.	.	PUNCT
admet-2366	616	1	biomaterials	biomaterial	NOUN
admet-2366	616	2	31	31	NUM
admet-2366	616	3	(	(	PUNCT
admet-2366	616	4	2010	2010	NUM
admet-2366	616	5	)	)	PUNCT
admet-2366	616	6	3657	3657	NUM
admet-2366	616	7	-	-	SYM
admet-2366	616	8	3666	3666	NUM
admet-2366	616	9	.	.	PUNCT
admet-2366	617	1	https://doi.org/10.1016/j.biomaterials.2010.01.065	https://doi.org/10.1016/j.biomaterials.2010.01.065	NOUN
admet-2366	617	2	.	.	PUNCT
admet-2366	618	1	https://doi.org/10.1016/j.tube.2020.102008	https://doi.org/10.1016/j.tube.2020.102008	VERB
admet-2366	618	2	https://doi.org/10.1080/00914037.2020.1765350	https://doi.org/10.1080/00914037.2020.1765350	PROPN
admet-2366	618	3	https://doi.org/10.3109/10717544.2016.1149744	https://doi.org/10.3109/10717544.2016.1149744	VERB
admet-2366	618	4	https://doi.org/10.1007/s10928-011-9198-0	https://doi.org/10.1007/s10928-011-9198-0	NUM
admet-2366	618	5	https://doi.org/10.1080/10717544.2017.1384862	https://doi.org/10.1080/10717544.2017.1384862	NOUN
admet-2366	618	6	https://doi.org/10.3390/pharmaceutics12100939	https://doi.org/10.3390/pharmaceutics12100939	NOUN
admet-2366	618	7	https://doi.org/10.3390/ijms23084249	https://doi.org/10.3390/ijms23084249	PROPN
admet-2366	618	8	https://doi.org/10.1080/21691401.2017.1337029	https://doi.org/10.1080/21691401.2017.1337029	PROPN
admet-2366	618	9	https://doi.org/10.1007/978-1-60327-360-2_2	https://doi.org/10.1007/978-1-60327-360-2_2	PROPN
admet-2366	618	10	https://doi.org/10.1080/00914037.2020.1765350	https://doi.org/10.1080/00914037.2020.1765350	PROPN
admet-2366	618	11	https://doi.org/10.1371/journal.pone.0025433	https://doi.org/10.1371/journal.pone.0025433	PRON
admet-2366	618	12	https://doi.org/10.5713/ajas.14.0761	https://doi.org/10.5713/ajas.14.0761	VERB
admet-2366	618	13	https://doi.org/10.1016/j.biomaterials.2010.01.065	https://doi.org/10.1016/j.biomaterials.2010.01.065	PRON
admet-2366	618	14	admet	admet	PROPN
admet-2366	618	15	&	&	CCONJ
admet-2366	618	16	dmpk	dmpk	PROPN
admet-2366	618	17	12(4	12(4	PROPN
admet-2366	618	18	)	)	PUNCT
admet-2366	618	19	(	(	PUNCT
admet-2366	618	20	2024	2024	NUM
admet-2366	618	21	)	)	PUNCT
admet-2366	618	22	657	657	NUM
admet-2366	618	23	-	-	SYM
admet-2366	618	24	677	677	NUM
admet-2366	618	25	optimizing	optimizing	NOUN
admet-2366	618	26	gefitinib	gefitinib	NOUN
admet-2366	618	27	nanoliposomes	nanoliposomes	ADV
admet-2366	618	28	doi	doi	ADV
admet-2366	618	29	:	:	PUNCT
admet-2366	618	30	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	PROPN
admet-2366	618	31	677	677	NUM
admet-2366	619	1	[	[	X
admet-2366	619	2	58	58	NUM
admet-2366	619	3	]	]	PUNCT
admet-2366	619	4	s.	s.	PROPN
admet-2366	619	5	gulzar	gulzar	PROPN
admet-2366	619	6	,	,	PUNCT
admet-2366	619	7	s.	s.	PROPN
admet-2366	619	8	benjakul	benjakul	PROPN
admet-2366	619	9	.	.	PUNCT
admet-2366	620	1	characteristics	characteristic	NOUN
admet-2366	620	2	and	and	CCONJ
admet-2366	620	3	storage	storage	NOUN
admet-2366	620	4	stability	stability	NOUN
admet-2366	620	5	of	of	ADP
admet-2366	620	6	nanoliposomes	nanoliposome	NOUN
admet-2366	620	7	loaded	load	VERB
admet-2366	620	8	with	with	ADP
admet-2366	620	9	shrimp	shrimp	NOUN
admet-2366	620	10	oil	oil	NOUN
admet-2366	620	11	as	as	SCONJ
admet-2366	620	12	affected	affect	VERB
admet-2366	620	13	by	by	ADP
admet-2366	620	14	ultrasonication	ultrasonication	NOUN
admet-2366	620	15	and	and	CCONJ
admet-2366	620	16	microfluidization	microfluidization	NOUN
admet-2366	620	17	.	.	PUNCT
admet-2366	621	1	food	food	NOUN
admet-2366	621	2	chemistry	chemistry	NOUN
admet-2366	621	3	310	310	NUM
admet-2366	621	4	(	(	PUNCT
admet-2366	621	5	2020	2020	NUM
admet-2366	621	6	)	)	PUNCT
admet-2366	621	7	125916	125916	NUM
admet-2366	621	8	.	.	PUNCT
admet-2366	622	1	https://doi.org/10.1016/j.foodchem.2019.125916	https://doi.org/10.1016/j.foodchem.2019.125916	PROPN
admet-2366	622	2	.	.	PUNCT
admet-2366	623	1	[	[	X
admet-2366	623	2	59	59	NUM
admet-2366	623	3	]	]	PUNCT
admet-2366	623	4	x.	x.	PROPN
admet-2366	623	5	chen	chen	PROPN
admet-2366	623	6	,	,	PUNCT
admet-2366	623	7	l.q	l.q	PROPN
admet-2366	623	8	.	.	PROPN
admet-2366	623	9	zou	zou	PROPN
admet-2366	623	10	,	,	PUNCT
admet-2366	623	11	j.	j.	PROPN
admet-2366	623	12	niu	niu	PROPN
admet-2366	623	13	,	,	PUNCT
admet-2366	623	14	w.	w.	PROPN
admet-2366	623	15	liu	liu	PROPN
admet-2366	623	16	,	,	PUNCT
admet-2366	623	17	s.f	s.f	PROPN
admet-2366	623	18	.	.	PROPN
admet-2366	623	19	peng	peng	PROPN
admet-2366	623	20	,	,	PUNCT
admet-2366	623	21	c.m	c.m	PROPN
admet-2366	623	22	.	.	PROPN
admet-2366	623	23	liu	liu	PROPN
admet-2366	623	24	.	.	PUNCT
admet-2366	624	1	the	the	DET
admet-2366	624	2	stability	stability	NOUN
admet-2366	624	3	,	,	PUNCT
admet-2366	624	4	sustained	sustain	VERB
admet-2366	624	5	release	release	NOUN
admet-2366	624	6	and	and	CCONJ
admet-2366	624	7	cellular	cellular	ADJ
admet-2366	624	8	antioxidant	antioxidant	ADJ
admet-2366	624	9	activity	activity	NOUN
admet-2366	624	10	of	of	ADP
admet-2366	624	11	curcumin	curcumin	NOUN
admet-2366	624	12	nanoliposomes	nanoliposome	NOUN
admet-2366	624	13	.	.	PUNCT
admet-2366	625	1	molecules	molecule	NOUN
admet-2366	625	2	20	20	NUM
admet-2366	625	3	(	(	PUNCT
admet-2366	625	4	2015	2015	NUM
admet-2366	625	5	)	)	PUNCT
admet-2366	625	6	14293	14293	NUM
admet-2366	625	7	-	-	SYM
admet-2366	625	8	14311	14311	NUM
admet-2366	625	9	.	.	PUNCT
admet-2366	626	1	https://doi.org/10.3390/molecules200814293	https://doi.org/10.3390/molecules200814293	NOUN
admet-2366	626	2	.	.	PUNCT
admet-2366	627	1	©	©	PROPN
admet-2366	627	2	2024	2024	NUM
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admet-2366	627	4	the	the	DET
admet-2366	627	5	authors	author	NOUN
admet-2366	627	6	;	;	PUNCT
admet-2366	627	7	licensee	licensee	PROPN
admet-2366	627	8	iapc	iapc	PROPN
admet-2366	627	9	,	,	PUNCT
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admet-2366	627	11	,	,	PUNCT
admet-2366	627	12	croatia	croatia	PROPN
admet-2366	627	13	.	.	PUNCT
admet-2366	628	1	this	this	DET
admet-2366	628	2	article	article	NOUN
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admet-2366	628	4	an	an	DET
admet-2366	628	5	open	open	ADJ
admet-2366	628	6	-	-	PUNCT
admet-2366	628	7	access	access	NOUN
admet-2366	628	8	article	article	NOUN
admet-2366	628	9	distributed	distribute	VERB
admet-2366	628	10	under	under	ADP
admet-2366	628	11	the	the	DET
admet-2366	628	12	terms	term	NOUN
admet-2366	628	13	and	and	CCONJ
admet-2366	628	14	conditions	condition	NOUN
admet-2366	628	15	of	of	ADP
admet-2366	628	16	the	the	DET
admet-2366	628	17	creative	creative	ADJ
admet-2366	628	18	commons	common	NOUN
admet-2366	628	19	attribution	attribution	NOUN
admet-2366	628	20	license	license	NOUN
admet-2366	628	21	(	(	PUNCT
admet-2366	628	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-2366	628	23	)	)	PUNCT
admet-2366	629	1	https://doi.org/10.5599/admet.2366	https://doi.org/10.5599/admet.2366	VERB
admet-2366	629	2	https://doi.org/10.1016/j.foodchem.2019.125916	https://doi.org/10.1016/j.foodchem.2019.125916	PROPN
admet-2366	629	3	https://doi.org/10.3390/molecules200814293	https://doi.org/10.3390/molecules200814293	NOUN
admet-2366	629	4	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN