id	sid	tid	token	lemma	pos
admet-24	1	1	manuscript	manuscript	PROPN
admet-24	1	2	doi	doi	PROPN
admet-24	1	3	:	:	PUNCT
admet-24	1	4	10.5599	10.5599	NUM
admet-24	1	5	/	/	SYM
admet-24	1	6	admet.1.4.24	admet.1.4.24	PROPN
admet-24	1	7	48	48	NUM
admet-24	1	8	admet	admet	X
admet-24	1	9	&	&	CCONJ
admet-24	1	10	dmpk	dmpk	PROPN
admet-24	1	11	1(4	1(4	NUM
admet-24	1	12	)	)	PUNCT
admet-24	1	13	(	(	PUNCT
admet-24	1	14	2013	2013	NUM
admet-24	1	15	)	)	PUNCT
admet-24	1	16	48	48	NUM
admet-24	1	17	-	-	SYM
admet-24	1	18	62	62	NUM
admet-24	1	19	;	;	PUNCT
admet-24	1	20	doi	doi	NOUN
admet-24	1	21	:	:	PUNCT
admet-24	1	22	10.5599	10.5599	NUM
admet-24	1	23	/	/	SYM
admet-24	1	24	admet.1.4.24	admet.1.4.24	NOUN
admet-24	1	25	open	open	ADJ
admet-24	1	26	access	access	NOUN
admet-24	1	27	:	:	PUNCT
admet-24	1	28	issn	issn	PROPN
admet-24	1	29	:	:	PUNCT
admet-24	1	30	1848	1848	NUM
admet-24	1	31	-	-	SYM
admet-24	1	32	7718	7718	NUM
admet-24	1	33	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-24	1	34	original	original	ADJ
admet-24	1	35	scientific	scientific	ADJ
admet-24	1	36	paper	paper	NOUN
admet-24	1	37	salt	salt	NOUN
admet-24	1	38	solubility	solubility	NOUN
admet-24	1	39	products	product	NOUN
admet-24	1	40	of	of	ADP
admet-24	1	41	diprenorphine	diprenorphine	NOUN
admet-24	1	42	hydrochloride	hydrochloride	NOUN
admet-24	1	43	,	,	PUNCT
admet-24	1	44	codeine	codeine	NOUN
admet-24	1	45	and	and	CCONJ
admet-24	1	46	lidocaine	lidocaine	NOUN
admet-24	1	47	hydrochlorides	hydrochloride	NOUN
admet-24	1	48	and	and	CCONJ
admet-24	1	49	phosphates	phosphate	NOUN
admet-24	1	50	–	–	PUNCT
admet-24	1	51	novel	novel	NOUN
admet-24	1	52	method	method	NOUN
admet-24	1	53	of	of	ADP
admet-24	1	54	data	datum	NOUN
admet-24	1	55	analysis	analysis	NOUN
admet-24	1	56	not	not	PART
admet-24	1	57	dependent	dependent	ADJ
admet-24	1	58	on	on	ADP
admet-24	1	59	explicit	explicit	ADJ
admet-24	1	60	solubility	solubility	NOUN
admet-24	1	61	equations	equation	NOUN
admet-24	1	62	gergely	gergely	ADV
admet-24	1	63	völgyi1	völgyi1	ADJ
admet-24	1	64	,	,	PUNCT
admet-24	1	65	attila	attila	PROPN
admet-24	1	66	marosi1	marosi1	PROPN
admet-24	1	67	,	,	PUNCT
admet-24	1	68	krisztina	krisztina	PROPN
admet-24	1	69	takács	takács	PROPN
admet-24	1	70	-	-	PUNCT
admet-24	1	71	novák1	novák1	PROPN
admet-24	1	72	,	,	PUNCT
admet-24	1	73	alex	alex	PROPN
admet-24	1	74	avdeef2	avdeef2	PROPN
admet-24	1	75	*	*	PROPN
admet-24	1	76	1	1	NUM
admet-24	1	77	semmelweis	semmelweis	NOUN
admet-24	1	78	university	university	NOUN
admet-24	1	79	,	,	PUNCT
admet-24	1	80	department	department	NOUN
admet-24	1	81	of	of	ADP
admet-24	1	82	pharmaceutical	pharmaceutical	ADJ
admet-24	1	83	chemistry	chemistry	NOUN
admet-24	1	84	h-1092	h-1092	PROPN
admet-24	1	85	hőgyes	hőgyes	ADV
admet-24	1	86	endre	endre	PROPN
admet-24	1	87	street	street	PROPN
admet-24	1	88	9	9	NUM
admet-24	1	89	.	.	PUNCT
admet-24	2	1	budapest	budapest	PROPN
admet-24	2	2	,	,	PUNCT
admet-24	2	3	hungary	hungary	NOUN
admet-24	2	4	2	2	NUM
admet-24	2	5	in	in	ADP
admet-24	2	6	-	-	PUNCT
admet-24	2	7	adme	adme	NOUN
admet-24	2	8	research	research	NOUN
admet-24	2	9	,	,	PUNCT
admet-24	2	10	1732	1732	NUM
admet-24	2	11	first	first	ADJ
admet-24	2	12	avenue	avenue	PROPN
admet-24	2	13	,	,	PUNCT
admet-24	2	14	#	#	SYM
admet-24	2	15	102	102	NUM
admet-24	2	16	,	,	PUNCT
admet-24	2	17	new	new	PROPN
admet-24	2	18	york	york	PROPN
admet-24	2	19	,	,	PUNCT
admet-24	2	20	ny	ny	PROPN
admet-24	2	21	10128	10128	NUM
admet-24	2	22	,	,	PUNCT
admet-24	2	23	usa	usa	PROPN
admet-24	2	24	*	*	PUNCT
admet-24	2	25	corresponding	correspond	VERB
admet-24	2	26	author	author	NOUN
admet-24	2	27	:	:	PUNCT
admet-24	2	28	alex	alex	PROPN
admet-24	2	29	avdeef	avdeef	PROPN
admet-24	2	30	;	;	PUNCT
admet-24	2	31	e	e	X
admet-24	2	32	-	-	NOUN
admet-24	2	33	mail	mail	NOUN
admet-24	2	34	:	:	PUNCT
admet-24	2	35	alex@in-adme.com	alex@in-adme.com	NOUN
admet-24	2	36	;	;	PUNCT
admet-24	2	37	tel	tel	PROPN
admet-24	2	38	.	.	PUNCT
admet-24	2	39	:	:	PUNCT
admet-24	3	1	+1	+1	PROPN
admet-24	3	2	647	647	NUM
admet-24	3	3	678	678	NUM
admet-24	3	4	5713	5713	NUM
admet-24	3	5	;	;	PUNCT
admet-24	3	6	received	receive	VERB
admet-24	3	7	:	:	PUNCT
admet-24	3	8	december	december	PROPN
admet-24	3	9	6	6	NUM
admet-24	3	10	,	,	PUNCT
admet-24	3	11	2013	2013	NUM
admet-24	3	12	;	;	PUNCT
admet-24	3	13	revised	revise	VERB
admet-24	3	14	:	:	PUNCT
admet-24	3	15	december	december	PROPN
admet-24	3	16	11	11	NUM
admet-24	3	17	,	,	PUNCT
admet-24	3	18	2013	2013	NUM
admet-24	3	19	;	;	PUNCT
admet-24	3	20	published	publish	VERB
admet-24	3	21	:	:	PUNCT
admet-24	3	22	december	december	PROPN
admet-24	3	23	16	16	NUM
admet-24	3	24	,	,	PUNCT
admet-24	3	25	2013	2013	NUM
admet-24	3	26	abstract	abstract	NOUN
admet-24	3	27	a	a	DET
admet-24	3	28	novel	novel	ADJ
admet-24	3	29	general	general	ADJ
admet-24	3	30	approach	approach	NOUN
admet-24	3	31	was	be	AUX
admet-24	3	32	described	describe	VERB
admet-24	3	33	to	to	PART
admet-24	3	34	address	address	VERB
admet-24	3	35	many	many	ADJ
admet-24	3	36	of	of	ADP
admet-24	3	37	the	the	DET
admet-24	3	38	challenges	challenge	NOUN
admet-24	3	39	of	of	ADP
admet-24	3	40	salt	salt	NOUN
admet-24	3	41	solubility	solubility	NOUN
admet-24	3	42	determination	determination	NOUN
admet-24	3	43	of	of	ADP
admet-24	3	44	drug	drug	NOUN
admet-24	3	45	substances	substance	NOUN
admet-24	3	46	,	,	PUNCT
admet-24	3	47	with	with	ADP
admet-24	3	48	data	datum	NOUN
admet-24	3	49	processing	processing	NOUN
admet-24	3	50	and	and	CCONJ
admet-24	3	51	refinement	refinement	NOUN
admet-24	3	52	of	of	ADP
admet-24	3	53	equilibrium	equilibrium	NOUN
admet-24	3	54	constants	constant	NOUN
admet-24	3	55	encoded	encode	VERB
admet-24	3	56	in	in	ADP
admet-24	3	57	the	the	DET
admet-24	3	58	computer	computer	NOUN
admet-24	3	59	program	program	NOUN
admet-24	3	60	pdisolx	pdisolx	PROPN
admet-24	3	61	tm	tm	PROPN
admet-24	3	62	.	.	PUNCT
admet-24	4	1	the	the	DET
admet-24	4	2	new	new	ADJ
admet-24	4	3	approach	approach	NOUN
admet-24	4	4	was	be	AUX
admet-24	4	5	illustrated	illustrate	VERB
admet-24	4	6	by	by	ADP
admet-24	4	7	the	the	DET
admet-24	4	8	determinations	determination	NOUN
admet-24	4	9	of	of	ADP
admet-24	4	10	the	the	DET
admet-24	4	11	solubility	solubility	NOUN
admet-24	4	12	products	product	NOUN
admet-24	4	13	of	of	ADP
admet-24	4	14	diprenorphine	diprenorphine	NOUN
admet-24	4	15	hydrochloride	hydrochloride	NOUN
admet-24	4	16	,	,	PUNCT
admet-24	4	17	codeine	codeine	NOUN
admet-24	4	18	hydrochloride	hydrochloride	NOUN
admet-24	4	19	and	and	CCONJ
admet-24	4	20	phosphate	phosphate	VERB
admet-24	4	21	,	,	PUNCT
admet-24	4	22	lidocaine	lidocaine	NOUN
admet-24	4	23	hydrochloride	hydrochloride	NOUN
admet-24	4	24	and	and	CCONJ
admet-24	4	25	phosphate	phosphate	VERB
admet-24	4	26	at	at	ADP
admet-24	4	27	25	25	NUM
admet-24	4	28	o	o	NOUN
admet-24	4	29	c	c	NOUN
admet-24	4	30	,	,	PUNCT
admet-24	4	31	using	use	VERB
admet-24	4	32	a	a	DET
admet-24	4	33	recently	recently	ADV
admet-24	4	34	-	-	PUNCT
admet-24	4	35	optimized	optimize	VERB
admet-24	4	36	saturation	saturation	NOUN
admet-24	4	37	shake	shake	NOUN
admet-24	4	38	-	-	PUNCT
admet-24	4	39	flask	flask	NOUN
admet-24	4	40	protocol	protocol	NOUN
admet-24	4	41	.	.	PUNCT
admet-24	5	1	the	the	DET
admet-24	5	2	effects	effect	NOUN
admet-24	5	3	of	of	ADP
admet-24	5	4	different	different	ADJ
admet-24	5	5	buffers	buffer	NOUN
admet-24	5	6	(	(	PUNCT
admet-24	5	7	britton	britton	PROPN
admet-24	5	8	-	-	PUNCT
admet-24	5	9	robinson	robinson	PROPN
admet-24	5	10	universal	universal	ADJ
admet-24	5	11	and	and	CCONJ
admet-24	5	12	sörensen	sörensen	ADJ
admet-24	5	13	phosphate	phosphate	NOUN
admet-24	5	14	)	)	PUNCT
admet-24	5	15	were	be	AUX
admet-24	5	16	compared	compare	VERB
admet-24	5	17	.	.	PUNCT
admet-24	6	1	lidocaine	lidocaine	NOUN
admet-24	6	2	precipitates	precipitate	NOUN
admet-24	6	3	were	be	AUX
admet-24	6	4	characterized	characterize	VERB
admet-24	6	5	by	by	ADP
admet-24	6	6	x	x	NOUN
admet-24	6	7	-	-	NOUN
admet-24	6	8	ray	ray	NOUN
admet-24	6	9	powder	powder	NOUN
admet-24	6	10	diffraction	diffraction	NOUN
admet-24	6	11	(	(	PUNCT
admet-24	6	12	xrpd	xrpd	ADJ
admet-24	6	13	)	)	PUNCT
admet-24	6	14	and	and	CCONJ
admet-24	6	15	polarization	polarization	NOUN
admet-24	6	16	light	light	NOUN
admet-24	6	17	microscopy	microscopy	NOUN
admet-24	6	18	.	.	PUNCT
admet-24	7	1	the	the	DET
admet-24	7	2	ionic	ionic	ADJ
admet-24	7	3	strength	strength	NOUN
admet-24	7	4	in	in	ADP
admet-24	7	5	the	the	DET
admet-24	7	6	studied	study	VERB
admet-24	7	7	systems	system	NOUN
admet-24	7	8	ranged	range	VERB
admet-24	7	9	from	from	ADP
admet-24	7	10	0.25	0.25	NUM
admet-24	7	11	to	to	ADP
admet-24	7	12	4.3	4.3	NUM
admet-24	7	13	m.	m.	NOUN
admet-24	7	14	codeine	codeine	NOUN
admet-24	7	15	(	(	PUNCT
admet-24	7	16	and	and	CCONJ
admet-24	7	17	possibly	possibly	ADV
admet-24	7	18	diprenorphine	diprenorphine	NOUN
admet-24	7	19	)	)	PUNCT
admet-24	7	20	chloride	chloride	NOUN
admet-24	7	21	were	be	AUX
admet-24	7	22	less	less	ADV
admet-24	7	23	soluble	soluble	ADJ
admet-24	7	24	than	than	ADP
admet-24	7	25	the	the	DET
admet-24	7	26	phosphates	phosphate	NOUN
admet-24	7	27	for	for	ADP
admet-24	7	28	ph	ph	PROPN
admet-24	7	29	>	>	X
admet-24	7	30	2	2	NUM
admet-24	7	31	.	.	PUNCT
admet-24	8	1	the	the	DET
admet-24	8	2	reverse	reverse	ADJ
admet-24	8	3	trend	trend	NOUN
admet-24	8	4	was	be	AUX
admet-24	8	5	evident	evident	ADJ
admet-24	8	6	with	with	ADP
admet-24	8	7	lidocaine	lidocaine	NOUN
admet-24	8	8	.	.	PUNCT
admet-24	9	1	diprenorphine	diprenorphine	NOUN
admet-24	9	2	saturated	saturate	VERB
admet-24	9	3	solutions	solution	NOUN
admet-24	9	4	showed	show	VERB
admet-24	9	5	departure	departure	NOUN
admet-24	9	6	from	from	ADP
admet-24	9	7	the	the	DET
admet-24	9	8	predictions	prediction	NOUN
admet-24	9	9	of	of	ADP
admet-24	9	10	the	the	DET
admet-24	9	11	henderson	henderson	PROPN
admet-24	9	12	-	-	PUNCT
admet-24	9	13	hasselbalch	hasselbalch	PROPN
admet-24	9	14	equation	equation	NOUN
admet-24	9	15	in	in	ADP
admet-24	9	16	alkaline	alkaline	NOUN
admet-24	9	17	(	(	PUNCT
admet-24	9	18	ph	ph	X
admet-24	9	19	>	>	SYM
admet-24	9	20	9	9	NUM
admet-24	9	21	)	)	PUNCT
admet-24	9	22	solutions	solution	NOUN
admet-24	9	23	,	,	PUNCT
admet-24	9	24	consistent	consistent	ADJ
admet-24	9	25	with	with	ADP
admet-24	9	26	the	the	DET
admet-24	9	27	formation	formation	NOUN
admet-24	9	28	of	of	ADP
admet-24	9	29	a	a	DET
admet-24	9	30	mixed	mixed	ADJ
admet-24	9	31	-	-	PUNCT
admet-24	9	32	charge	charge	NOUN
admet-24	9	33	anionic	anionic	ADJ
admet-24	9	34	dimer	dimer	NOUN
admet-24	9	35	.	.	PUNCT
admet-24	10	1	keywords	keyword	NOUN
admet-24	10	2	sparingly	sparingly	ADV
admet-24	10	3	-	-	PUNCT
admet-24	10	4	soluble	soluble	ADJ
admet-24	10	5	drugs	drug	NOUN
admet-24	10	6	;	;	PUNCT
admet-24	10	7	ph	ph	ADJ
admet-24	10	8	-	-	PUNCT
admet-24	10	9	dependent	dependent	ADJ
admet-24	10	10	solubility	solubility	NOUN
admet-24	10	11	;	;	PUNCT
admet-24	10	12	salt	salt	NOUN
admet-24	10	13	solubility	solubility	NOUN
admet-24	10	14	products	product	NOUN
admet-24	10	15	,	,	PUNCT
admet-24	10	16	solubility	solubility	NOUN
admet-24	10	17	equations	equation	NOUN
admet-24	10	18	;	;	PUNCT
admet-24	10	19	aggregation	aggregation	NOUN
admet-24	10	20	;	;	PUNCT
admet-24	10	21	shake	shake	NOUN
admet-24	10	22	-	-	PUNCT
admet-24	10	23	flask	flask	NOUN
admet-24	10	24	method	method	NOUN
admet-24	10	25	.	.	PUNCT
admet-24	11	1	introduction	introduction	NOUN
admet-24	11	2	salt	salt	NOUN
admet-24	11	3	selection	selection	NOUN
admet-24	11	4	in	in	ADP
admet-24	11	5	preformulation	preformulation	NOUN
admet-24	11	6	is	be	AUX
admet-24	11	7	an	an	DET
admet-24	11	8	important	important	ADJ
admet-24	11	9	step	step	NOUN
admet-24	11	10	in	in	ADP
admet-24	11	11	the	the	DET
admet-24	11	12	preparation	preparation	NOUN
admet-24	11	13	of	of	ADP
admet-24	11	14	effective	effective	ADJ
admet-24	11	15	oral	oral	ADJ
admet-24	11	16	drug	drug	NOUN
admet-24	11	17	formulations	formulation	NOUN
admet-24	11	18	[	[	X
admet-24	11	19	1	1	NUM
admet-24	11	20	-	-	SYM
admet-24	11	21	8	8	NUM
admet-24	11	22	]	]	PUNCT
admet-24	11	23	.	.	PUNCT
admet-24	12	1	salt	salt	NOUN
admet-24	12	2	solubility	solubility	PROPN
admet-24	12	3	,	,	PUNCT
admet-24	12	4	being	be	AUX
admet-24	12	5	a	a	DET
admet-24	12	6	conditional	conditional	ADJ
admet-24	12	7	constant	constant	ADJ
admet-24	12	8	,	,	PUNCT
admet-24	12	9	takes	take	VERB
admet-24	12	10	on	on	ADP
admet-24	12	11	different	different	ADJ
admet-24	12	12	values	value	NOUN
admet-24	12	13	according	accord	VERB
admet-24	12	14	to	to	ADP
admet-24	12	15	the	the	DET
admet-24	12	16	concentrations	concentration	NOUN
admet-24	12	17	and	and	CCONJ
admet-24	12	18	types	type	NOUN
admet-24	12	19	of	of	ADP
admet-24	12	20	reactants	reactant	NOUN
admet-24	12	21	used	use	VERB
admet-24	12	22	in	in	ADP
admet-24	12	23	a	a	DET
admet-24	12	24	particular	particular	ADJ
admet-24	12	25	study	study	NOUN
admet-24	12	26	.	.	PUNCT
admet-24	13	1	for	for	ADP
admet-24	13	2	this	this	DET
admet-24	13	3	reason	reason	NOUN
admet-24	13	4	,	,	PUNCT
admet-24	13	5	laboratory	laboratory	NOUN
admet-24	13	6	-	-	PUNCT
admet-24	13	7	to	to	ADP
admet-24	13	8	-	-	PUNCT
admet-24	13	9	laboratory	laboratory	NOUN
admet-24	13	10	comparisons	comparison	NOUN
admet-24	13	11	can	can	AUX
admet-24	13	12	be	be	AUX
admet-24	13	13	complicated	complicate	VERB
admet-24	13	14	,	,	PUNCT
admet-24	13	15	possibly	possibly	ADV
admet-24	13	16	leading	lead	VERB
admet-24	13	17	to	to	ADP
admet-24	13	18	conflicting	conflicting	ADJ
admet-24	13	19	interpretations	interpretation	NOUN
admet-24	13	20	of	of	ADP
admet-24	13	21	in	in	ADP
admet-24	13	22	vitro	vitro	X
admet-24	13	23	dissolution	dissolution	NOUN
admet-24	13	24	studies	study	NOUN
admet-24	13	25	in	in	ADP
admet-24	13	26	formulation	formulation	NOUN
admet-24	13	27	development	development	NOUN
admet-24	13	28	.	.	PUNCT
admet-24	14	1	on	on	ADP
admet-24	14	2	the	the	DET
admet-24	14	3	other	other	ADJ
admet-24	14	4	hand	hand	NOUN
admet-24	14	5	,	,	PUNCT
admet-24	14	6	salt	salt	NOUN
admet-24	14	7	solubility	solubility	NOUN
admet-24	14	8	products	product	NOUN
admet-24	14	9	are	be	AUX
admet-24	14	10	true	true	ADJ
admet-24	14	11	equilibrium	equilibrium	NOUN
admet-24	14	12	constants	constant	NOUN
admet-24	14	13	.	.	PUNCT
admet-24	15	1	but	but	CCONJ
admet-24	15	2	these	these	PRON
admet-24	15	3	are	be	AUX
admet-24	15	4	not	not	PART
admet-24	15	5	often	often	ADV
admet-24	15	6	reported	report	VERB
admet-24	15	7	in	in	ADP
admet-24	15	8	published	publish	VERB
admet-24	15	9	salt	salt	NOUN
admet-24	15	10	solubility	solubility	NOUN
admet-24	15	11	studies	study	NOUN
admet-24	15	12	.	.	PUNCT
admet-24	16	1	interpretation	interpretation	NOUN
admet-24	16	2	and	and	CCONJ
admet-24	16	3	scaling	scaling	NOUN
admet-24	16	4	of	of	ADP
admet-24	16	5	salt	salt	NOUN
admet-24	16	6	solubility	solubility	NOUN
admet-24	16	7	measurements	measurement	NOUN
admet-24	16	8	can	can	AUX
admet-24	16	9	be	be	AUX
admet-24	16	10	very	very	ADV
admet-24	16	11	challenging	challenging	ADJ
admet-24	16	12	for	for	ADP
admet-24	16	13	a	a	DET
admet-24	16	14	number	number	NOUN
admet-24	16	15	of	of	ADP
admet-24	16	16	reasons	reason	NOUN
admet-24	16	17	.	.	PUNCT
admet-24	17	1	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-24	17	2	mailto:alex@in-adme.com	mailto:alex@in-adme.com	PROPN
admet-24	17	3	admet	admet	PROPN
admet-24	17	4	&	&	CCONJ
admet-24	17	5	dmpk	dmpk	PROPN
admet-24	17	6	1(4	1(4	NUM
admet-24	17	7	)	)	PUNCT
admet-24	17	8	(	(	PUNCT
admet-24	17	9	2013	2013	NUM
admet-24	17	10	)	)	PUNCT
admet-24	17	11	48	48	NUM
admet-24	17	12	-	-	SYM
admet-24	17	13	62	62	NUM
admet-24	17	14	novel	novel	NOUN
admet-24	17	15	method	method	NOUN
admet-24	17	16	of	of	ADP
admet-24	17	17	salt	salt	NOUN
admet-24	17	18	solubility	solubility	NOUN
admet-24	17	19	analysis	analysis	NOUN
admet-24	17	20	doi	doi	NOUN
admet-24	17	21	:	:	PUNCT
admet-24	17	22	10.5599	10.5599	NUM
admet-24	17	23	/	/	SYM
admet-24	17	24	admet.1.4.24	admet.1.4.24	PROPN
admet-24	17	25	49	49	NUM
admet-24	17	26			NOUN
admet-24	17	27	since	since	SCONJ
admet-24	17	28	drug	drug	NOUN
admet-24	17	29	salts	salt	NOUN
admet-24	17	30	are	be	AUX
admet-24	17	31	often	often	ADV
admet-24	17	32	much	much	ADV
admet-24	17	33	more	more	ADV
admet-24	17	34	soluble	soluble	ADJ
admet-24	17	35	than	than	ADP
admet-24	17	36	the	the	DET
admet-24	17	37	corresponding	corresponding	ADJ
admet-24	17	38	uncharged	uncharged	ADJ
admet-24	17	39	forms	form	NOUN
admet-24	17	40	,	,	PUNCT
admet-24	17	41	salt	salt	NOUN
admet-24	17	42	solubility	solubility	NOUN
admet-24	17	43	measurement	measurement	NOUN
admet-24	17	44	is	be	AUX
admet-24	17	45	usually	usually	ADV
admet-24	17	46	carried	carry	VERB
admet-24	17	47	out	out	ADP
admet-24	17	48	in	in	ADP
admet-24	17	49	relatively	relatively	ADV
admet-24	17	50	concentrated	concentrated	ADJ
admet-24	17	51	solutions	solution	NOUN
admet-24	17	52	,	,	PUNCT
admet-24	17	53	with	with	ADP
admet-24	17	54	ionic	ionic	ADJ
admet-24	17	55	strengths	strength	NOUN
admet-24	17	56	,	,	PUNCT
admet-24	17	57	i	i	PRON
admet-24	17	58	,	,	PUNCT
admet-24	17	59	often	often	ADV
admet-24	17	60	exceeding	exceed	VERB
admet-24	17	61	1	1	NUM
admet-24	17	62	m.	m.	NOUN
admet-24	17	63			NOUN
admet-24	17	64	at	at	ADP
admet-24	17	65	these	these	DET
admet-24	17	66	high	high	ADJ
admet-24	17	67	levels	level	NOUN
admet-24	17	68	,	,	PUNCT
admet-24	17	69	activity	activity	NOUN
admet-24	17	70	coefficients	coefficient	NOUN
admet-24	17	71	of	of	ADP
admet-24	17	72	ions	ion	NOUN
admet-24	17	73	are	be	AUX
admet-24	17	74	poorly	poorly	ADV
admet-24	17	75	controlled	control	VERB
admet-24	17	76	and	and	CCONJ
admet-24	17	77	can	can	AUX
admet-24	17	78	not	not	PART
admet-24	17	79	be	be	AUX
admet-24	17	80	accurately	accurately	ADV
admet-24	17	81	predicted	predict	VERB
admet-24	17	82	by	by	ADP
admet-24	17	83	the	the	DET
admet-24	17	84	traditional	traditional	ADJ
admet-24	17	85	debye	debye	ADJ
admet-24	17	86	-	-	PUNCT
admet-24	17	87	hückel	hückel	NOUN
admet-24	17	88	equation	equation	NOUN
admet-24	17	89	.	.	PUNCT
admet-24	18	1			PROPN
admet-24	18	2	also	also	ADV
admet-24	18	3	,	,	PUNCT
admet-24	18	4	ph	ph	ADJ
admet-24	18	5	electrodes	electrode	NOUN
admet-24	18	6	calibrated	calibrate	VERB
admet-24	18	7	in	in	ADP
admet-24	18	8	buffers	buffer	NOUN
admet-24	18	9	with	with	ADP
admet-24	18	10	i	i	PROPN
admet-24	18	11	=	=	PUNCT
admet-24	18	12	0.15	0.15	NUM
admet-24	18	13	m	m	VERB
admet-24	18	14	(	(	PUNCT
admet-24	18	15	“	"	PUNCT
admet-24	18	16	physiological	physiological	ADJ
admet-24	18	17	”	"	PUNCT
admet-24	18	18	level	level	NOUN
admet-24	18	19	)	)	PUNCT
admet-24	18	20	may	may	AUX
admet-24	18	21	not	not	PART
admet-24	18	22	be	be	AUX
admet-24	18	23	accurate	accurate	ADJ
admet-24	18	24	at	at	ADP
admet-24	18	25	much	much	ADV
admet-24	18	26	higher	high	ADJ
admet-24	18	27	ionic	ionic	ADJ
admet-24	18	28	strengths	strength	NOUN
admet-24	18	29	,	,	PUNCT
admet-24	18	30	especially	especially	ADV
admet-24	18	31	in	in	ADP
admet-24	18	32	the	the	DET
admet-24	18	33	extreme	extreme	ADJ
admet-24	18	34	regions	region	NOUN
admet-24	18	35	of	of	ADP
admet-24	18	36	ph	ph	NOUN
admet-24	18	37	(	(	PUNCT
admet-24	18	38	<	<	X
admet-24	18	39	1	1	NUM
admet-24	18	40	or	or	CCONJ
admet-24	18	41	>	>	ADJ
admet-24	18	42	12	12	NUM
admet-24	18	43	)	)	PUNCT
admet-24	18	44	where	where	SCONJ
admet-24	18	45	electrode	electrode	NOUN
admet-24	18	46	junction	junction	NOUN
admet-24	18	47	potentials	potential	VERB
admet-24	18	48	may	may	AUX
admet-24	18	49	be	be	AUX
admet-24	18	50	very	very	ADV
admet-24	18	51	different	different	ADJ
admet-24	18	52	from	from	ADP
admet-24	18	53	those	those	DET
admet-24	18	54	characteristic	characteristic	NOUN
admet-24	18	55	of	of	ADP
admet-24	18	56	the	the	DET
admet-24	18	57	physiological	physiological	ADJ
admet-24	18	58	level	level	NOUN
admet-24	18	59	.	.	PUNCT
admet-24	19	1			X
admet-24	20	1	the	the	DET
admet-24	20	2	salt	salt	NOUN
admet-24	20	3	solubility	solubility	NOUN
admet-24	20	4	is	be	AUX
admet-24	20	5	a	a	DET
admet-24	20	6	conditional	conditional	ADJ
admet-24	20	7	constant	constant	NOUN
admet-24	20	8	,	,	PUNCT
admet-24	20	9	which	which	PRON
admet-24	20	10	depends	depend	VERB
admet-24	20	11	not	not	PART
admet-24	20	12	only	only	ADV
admet-24	20	13	on	on	ADP
admet-24	20	14	the	the	DET
admet-24	20	15	concentration	concentration	NOUN
admet-24	20	16	of	of	ADP
admet-24	20	17	the	the	DET
admet-24	20	18	drug	drug	NOUN
admet-24	20	19	but	but	CCONJ
admet-24	20	20	also	also	ADV
admet-24	20	21	on	on	ADP
admet-24	20	22	that	that	PRON
admet-24	20	23	of	of	ADP
admet-24	20	24	the	the	DET
admet-24	20	25	counterion	counterion	NOUN
admet-24	20	26	with	with	ADP
admet-24	20	27	which	which	PRON
admet-24	20	28	the	the	DET
admet-24	20	29	charged	charge	VERB
admet-24	20	30	drug	drug	NOUN
admet-24	20	31	precipitates	precipitate	NOUN
admet-24	20	32	.	.	PUNCT
admet-24	21	1	the	the	DET
admet-24	21	2	counterion	counterion	NOUN
admet-24	21	3	may	may	AUX
admet-24	21	4	originate	originate	VERB
admet-24	21	5	from	from	ADP
admet-24	21	6	the	the	DET
admet-24	21	7	buffer	buffer	NOUN
admet-24	21	8	used	use	VERB
admet-24	21	9	or	or	CCONJ
admet-24	21	10	other	other	ADJ
admet-24	21	11	unsuspecting	unsuspecting	ADJ
admet-24	21	12	solution	solution	NOUN
admet-24	21	13	additives	additive	NOUN
admet-24	21	14	.	.	PUNCT
admet-24	22	1			X
admet-24	22	2	under	under	ADP
admet-24	22	3	such	such	ADJ
admet-24	22	4	high	high	ADJ
admet-24	22	5	sample	sample	NOUN
admet-24	22	6	concentrations	concentration	NOUN
admet-24	22	7	,	,	PUNCT
admet-24	22	8	many	many	ADJ
admet-24	22	9	drugs	drug	NOUN
admet-24	22	10	,	,	PUNCT
admet-24	22	11	especially	especially	ADV
admet-24	22	12	those	those	PRON
admet-24	22	13	likely	likely	ADJ
admet-24	22	14	to	to	PART
admet-24	22	15	be	be	AUX
admet-24	22	16	surface	surface	NOUN
admet-24	22	17	-	-	PUNCT
admet-24	22	18	active	active	ADJ
admet-24	22	19	,	,	PUNCT
admet-24	22	20	can	can	AUX
admet-24	22	21	form	form	VERB
admet-24	22	22	micelles	micelle	NOUN
admet-24	22	23	,	,	PUNCT
admet-24	22	24	self	self	NOUN
admet-24	22	25	-	-	PUNCT
admet-24	22	26	associated	associate	VERB
admet-24	22	27	aggregates	aggregate	NOUN
admet-24	22	28	(	(	PUNCT
admet-24	22	29	dimers	dimer	NOUN
admet-24	22	30	,	,	PUNCT
admet-24	22	31	trimers	trimer	NOUN
admet-24	22	32	,	,	PUNCT
admet-24	22	33	or	or	CCONJ
admet-24	22	34	higher	high	ADJ
admet-24	22	35	-	-	PUNCT
admet-24	22	36	order	order	NOUN
admet-24	22	37	oligomers	oligomer	NOUN
admet-24	22	38	)	)	PUNCT
admet-24	22	39	,	,	PUNCT
admet-24	22	40	or	or	CCONJ
admet-24	22	41	complexes	complexe	VERB
admet-24	22	42	with	with	ADP
admet-24	22	43	buffer	buffer	NOUN
admet-24	22	44	species	specie	NOUN
admet-24	22	45	or	or	CCONJ
admet-24	22	46	other	other	ADJ
admet-24	22	47	solution	solution	NOUN
admet-24	22	48	additives	additive	NOUN
admet-24	22	49	.	.	PUNCT
admet-24	23	1	all	all	DET
admet-24	23	2	these	these	DET
admet-24	23	3	effects	effect	NOUN
admet-24	23	4	can	can	AUX
admet-24	23	5	complicate	complicate	VERB
admet-24	23	6	the	the	DET
admet-24	23	7	interpretation	interpretation	NOUN
admet-24	23	8	of	of	ADP
admet-24	23	9	the	the	DET
admet-24	23	10	solubility	solubility	NOUN
admet-24	23	11	data	datum	NOUN
admet-24	23	12	[	[	X
admet-24	23	13	9	9	NUM
admet-24	23	14	-	-	SYM
admet-24	23	15	18	18	NUM
admet-24	23	16	]	]	PUNCT
admet-24	23	17	.	.	PUNCT
admet-24	24	1	such	such	ADJ
admet-24	24	2	complexity	complexity	NOUN
admet-24	24	3	may	may	AUX
admet-24	24	4	not	not	PART
admet-24	24	5	be	be	AUX
admet-24	24	6	evident	evident	ADJ
admet-24	24	7	unless	unless	SCONJ
admet-24	24	8	a	a	DET
admet-24	24	9	full	full	ADJ
admet-24	24	10	solubility	solubility	NOUN
admet-24	24	11	–	–	PUNCT
admet-24	24	12	ph	ph	ADJ
admet-24	24	13	profile	profile	NOUN
admet-24	24	14	is	be	AUX
admet-24	24	15	measured	measure	VERB
admet-24	24	16	,	,	PUNCT
admet-24	24	17	over	over	ADP
admet-24	24	18	a	a	DET
admet-24	24	19	ph	ph	ADJ
admet-24	24	20	range	range	NOUN
admet-24	24	21	containing	contain	VERB
admet-24	24	22	the	the	DET
admet-24	24	23	uncharged	uncharged	ADJ
admet-24	24	24	and	and	CCONJ
admet-24	24	25	charged	charge	VERB
admet-24	24	26	forms	form	NOUN
admet-24	24	27	of	of	ADP
admet-24	24	28	the	the	DET
admet-24	24	29	drug	drug	NOUN
admet-24	24	30	,	,	PUNCT
admet-24	24	31	preferably	preferably	ADV
admet-24	24	32	at	at	ADP
admet-24	24	33	more	more	ADJ
admet-24	24	34	than	than	ADP
admet-24	24	35	one	one	NUM
admet-24	24	36	solid	solid	ADJ
admet-24	24	37	-	-	PUNCT
admet-24	24	38	sample	sample	NOUN
admet-24	24	39	excess	excess	NOUN
admet-24	24	40	.	.	PUNCT
admet-24	25	1	carefully	carefully	ADV
admet-24	25	2	planned	plan	VERB
admet-24	25	3	experimental	experimental	ADJ
admet-24	25	4	designs	design	NOUN
admet-24	25	5	and	and	CCONJ
admet-24	25	6	complicated	complicated	ADJ
admet-24	25	7	computations	computation	NOUN
admet-24	25	8	are	be	AUX
admet-24	25	9	often	often	ADV
admet-24	25	10	needed	need	VERB
admet-24	25	11	to	to	PART
admet-24	25	12	correctly	correctly	ADV
admet-24	25	13	interpret	interpret	VERB
admet-24	25	14	the	the	DET
admet-24	25	15	measured	measured	ADJ
admet-24	25	16	salt	salt	NOUN
admet-24	25	17	solubility	solubility	NOUN
admet-24	25	18	.	.	PUNCT
admet-24	26	1	although	although	SCONJ
admet-24	26	2	explicit	explicit	ADJ
admet-24	26	3	solubility	solubility	NOUN
admet-24	26	4	equations	equation	NOUN
admet-24	26	5	(	(	PUNCT
admet-24	26	6	cf	cf	NOUN
admet-24	26	7	.	.	PUNCT
admet-24	26	8	,	,	PUNCT
admet-24	26	9	appendix	appendix	VERB
admet-24	26	10	a	a	PRON
admet-24	26	11	)	)	PUNCT
admet-24	26	12	have	have	AUX
admet-24	26	13	been	be	AUX
admet-24	26	14	derived	derive	VERB
admet-24	26	15	for	for	ADP
admet-24	26	16	many	many	ADJ
admet-24	26	17	different	different	ADJ
admet-24	26	18	cases	case	NOUN
admet-24	26	19	of	of	ADP
admet-24	26	20	salt	salt	NOUN
admet-24	26	21	solubility	solubility	NOUN
admet-24	26	22	and	and	CCONJ
admet-24	26	23	aggregation	aggregation	NOUN
admet-24	26	24	[	[	X
admet-24	26	25	19	19	NUM
admet-24	26	26	]	]	PUNCT
admet-24	26	27	,	,	PUNCT
admet-24	26	28	it	it	PRON
admet-24	26	29	is	be	AUX
admet-24	26	30	hardly	hardly	ADV
admet-24	26	31	practical	practical	ADJ
admet-24	26	32	to	to	PART
admet-24	26	33	derive	derive	VERB
admet-24	26	34	such	such	ADJ
admet-24	26	35	equations	equation	NOUN
admet-24	26	36	for	for	ADP
admet-24	26	37	the	the	DET
admet-24	26	38	vast	vast	ADJ
admet-24	26	39	number	number	NOUN
admet-24	26	40	of	of	ADP
admet-24	26	41	possible	possible	ADJ
admet-24	26	42	forms	form	NOUN
admet-24	26	43	of	of	ADP
admet-24	26	44	salt	salt	NOUN
admet-24	26	45	and	and	CCONJ
admet-24	26	46	aggregation	aggregation	NOUN
admet-24	26	47	stoichiometry	stoichiometry	NOUN
admet-24	26	48	that	that	PRON
admet-24	26	49	can	can	AUX
admet-24	26	50	be	be	AUX
admet-24	26	51	encountered	encounter	VERB
admet-24	26	52	.	.	PUNCT
admet-24	27	1	for	for	ADP
admet-24	27	2	this	this	DET
admet-24	27	3	reason	reason	NOUN
admet-24	27	4	,	,	PUNCT
admet-24	27	5	salt	salt	NOUN
admet-24	27	6	solubility	solubility	NOUN
admet-24	27	7	analysis	analysis	NOUN
admet-24	27	8	of	of	ADP
admet-24	27	9	data	datum	NOUN
admet-24	27	10	in	in	ADP
admet-24	27	11	the	the	DET
admet-24	27	12	past	past	NOUN
admet-24	27	13	had	have	AUX
admet-24	27	14	been	be	AUX
admet-24	27	15	done	do	VERB
admet-24	27	16	on	on	ADP
admet-24	27	17	a	a	DET
admet-24	27	18	case	case	NOUN
admet-24	27	19	by	by	ADP
admet-24	27	20	case	case	NOUN
admet-24	27	21	basis	basis	NOUN
admet-24	27	22	,	,	PUNCT
admet-24	27	23	sometimes	sometimes	ADV
admet-24	27	24	using	use	VERB
admet-24	27	25	incomplete	incomplete	ADJ
admet-24	27	26	explicit	explicit	ADJ
admet-24	27	27	solubility	solubility	NOUN
admet-24	27	28	equations	equation	NOUN
admet-24	27	29	.	.	PUNCT
admet-24	28	1	at	at	ADP
admet-24	28	2	times	time	NOUN
admet-24	28	3	the	the	DET
admet-24	28	4	impact	impact	NOUN
admet-24	28	5	of	of	ADP
admet-24	28	6	aggregation	aggregation	NOUN
admet-24	28	7	reactions	reaction	NOUN
admet-24	28	8	had	have	AUX
admet-24	28	9	been	be	AUX
admet-24	28	10	recognized	recognize	VERB
admet-24	28	11	but	but	CCONJ
admet-24	28	12	not	not	PART
admet-24	28	13	dealt	deal	VERB
admet-24	28	14	with	with	ADP
admet-24	28	15	quantitatively	quantitatively	ADV
admet-24	28	16	,	,	PUNCT
admet-24	28	17	presumably	presumably	ADV
admet-24	28	18	because	because	SCONJ
admet-24	28	19	computational	computational	ADJ
admet-24	28	20	methods	method	NOUN
admet-24	28	21	were	be	AUX
admet-24	28	22	not	not	PART
admet-24	28	23	available	available	ADJ
admet-24	28	24	at	at	ADP
admet-24	28	25	the	the	DET
admet-24	28	26	time	time	NOUN
admet-24	28	27	[	[	X
admet-24	28	28	9,10,16	9,10,16	NUM
admet-24	28	29	]	]	PUNCT
admet-24	28	30	.	.	PUNCT
admet-24	29	1	in	in	ADP
admet-24	29	2	this	this	DET
admet-24	29	3	study	study	NOUN
admet-24	29	4	we	we	PRON
admet-24	29	5	describe	describe	VERB
admet-24	29	6	a	a	DET
admet-24	29	7	novel	novel	ADJ
admet-24	29	8	general	general	ADJ
admet-24	29	9	approach	approach	NOUN
admet-24	29	10	to	to	PART
admet-24	29	11	address	address	VERB
admet-24	29	12	many	many	ADJ
admet-24	29	13	of	of	ADP
admet-24	29	14	the	the	DET
admet-24	29	15	challenges	challenge	NOUN
admet-24	29	16	of	of	ADP
admet-24	29	17	salt	salt	NOUN
admet-24	29	18	solubility	solubility	NOUN
admet-24	29	19	determination	determination	NOUN
admet-24	29	20	,	,	PUNCT
admet-24	29	21	with	with	ADP
admet-24	29	22	data	datum	NOUN
admet-24	29	23	processing	processing	NOUN
admet-24	29	24	and	and	CCONJ
admet-24	29	25	refinement	refinement	NOUN
admet-24	29	26	of	of	ADP
admet-24	29	27	equilibrium	equilibrium	NOUN
admet-24	29	28	constants	constant	NOUN
admet-24	29	29	encoded	encode	VERB
admet-24	29	30	in	in	ADP
admet-24	29	31	the	the	DET
admet-24	29	32	computer	computer	NOUN
admet-24	29	33	program	program	NOUN
admet-24	29	34	pdisol	pdisol	ADV
admet-24	29	35	-	-	PUNCT
admet-24	29	36	xtm	xtm	PROPN
admet-24	29	37	(	(	PUNCT
admet-24	29	38	in	in	ADP
admet-24	29	39	-	-	PUNCT
admet-24	29	40	adme	adme	NOUN
admet-24	29	41	research	research	NOUN
admet-24	29	42	)	)	PUNCT
admet-24	29	43	.	.	PUNCT
admet-24	30	1	the	the	DET
admet-24	30	2	new	new	ADJ
admet-24	30	3	approach	approach	NOUN
admet-24	30	4	was	be	AUX
admet-24	30	5	illustrated	illustrate	VERB
admet-24	30	6	by	by	ADP
admet-24	30	7	the	the	DET
admet-24	30	8	determinations	determination	NOUN
admet-24	30	9	of	of	ADP
admet-24	30	10	the	the	DET
admet-24	30	11	solubility	solubility	NOUN
admet-24	30	12	products	product	NOUN
admet-24	30	13	of	of	ADP
admet-24	30	14	three	three	NUM
admet-24	30	15	model	model	NOUN
admet-24	30	16	drugs	drug	NOUN
admet-24	30	17	:	:	PUNCT
admet-24	30	18	diprenorphine	diprenorphine	NOUN
admet-24	30	19	hydrochloride	hydrochloride	NOUN
admet-24	30	20	,	,	PUNCT
admet-24	30	21	codeine	codeine	NOUN
admet-24	30	22	hydrochloride	hydrochloride	NOUN
admet-24	30	23	and	and	CCONJ
admet-24	30	24	phosphate	phosphate	VERB
admet-24	30	25	,	,	PUNCT
admet-24	30	26	lidocaine	lidocaine	NOUN
admet-24	30	27	hydrochloride	hydrochloride	NOUN
admet-24	30	28	and	and	CCONJ
admet-24	30	29	phosphate	phosphate	NOUN
admet-24	30	30	.	.	PUNCT
admet-24	31	1	diprenorphine	diprenorphine	NOUN
admet-24	31	2	,	,	PUNCT
admet-24	31	3	whose	whose	DET
admet-24	31	4	solubility	solubility	NOUN
admet-24	31	5	-	-	PUNCT
admet-24	31	6	ph	ph	NOUN
admet-24	31	7	profile	profile	NOUN
admet-24	31	8	had	have	AUX
admet-24	31	9	not	not	PART
admet-24	31	10	been	be	AUX
admet-24	31	11	reported	report	VERB
admet-24	31	12	,	,	PUNCT
admet-24	31	13	is	be	AUX
admet-24	31	14	primarily	primarily	ADV
admet-24	31	15	used	use	VERB
admet-24	31	16	as	as	ADP
admet-24	31	17	an	an	DET
admet-24	31	18	opioid	opioid	ADJ
admet-24	31	19	antagonist	antagonist	NOUN
admet-24	31	20	to	to	PART
admet-24	31	21	reverse	reverse	VERB
admet-24	31	22	the	the	DET
admet-24	31	23	effects	effect	NOUN
admet-24	31	24	of	of	ADP
admet-24	31	25	etorphine	etorphine	NOUN
admet-24	31	26	and	and	CCONJ
admet-24	31	27	carfentanyl	carfentanyl	PROPN
admet-24	31	28	.	.	PUNCT
admet-24	32	1	codeine	codeine	PROPN
admet-24	32	2	is	be	AUX
admet-24	32	3	a	a	DET
admet-24	32	4	naturally	naturally	ADV
admet-24	32	5	-	-	PUNCT
admet-24	32	6	occurring	occur	VERB
admet-24	32	7	analgesic	analgesic	ADJ
admet-24	32	8	opiate	opiate	ADJ
admet-24	32	9	.	.	PUNCT
admet-24	33	1	lidocaine	lidocaine	NOUN
admet-24	33	2	is	be	AUX
admet-24	33	3	a	a	DET
admet-24	33	4	local	local	ADJ
admet-24	33	5	anesthetic	anesthetic	NOUN
admet-24	33	6	.	.	PUNCT
admet-24	34	1	the	the	DET
admet-24	34	2	effects	effect	NOUN
admet-24	34	3	of	of	ADP
admet-24	34	4	different	different	ADJ
admet-24	34	5	buffers	buffer	NOUN
admet-24	34	6	(	(	PUNCT
admet-24	34	7	britton	britton	PROPN
admet-24	34	8	-	-	PUNCT
admet-24	34	9	robinson	robinson	PROPN
admet-24	34	10	universal	universal	ADJ
admet-24	34	11	and	and	CCONJ
admet-24	34	12	sörensen	sörensen	ADJ
admet-24	34	13	phosphate	phosphate	NOUN
admet-24	34	14	)	)	PUNCT
admet-24	34	15	were	be	AUX
admet-24	34	16	compared	compare	VERB
admet-24	34	17	.	.	PUNCT
admet-24	35	1	lidocaine	lidocaine	NOUN
admet-24	35	2	precipitates	precipitate	NOUN
admet-24	35	3	were	be	AUX
admet-24	35	4	characterized	characterize	VERB
admet-24	35	5	by	by	ADP
admet-24	35	6	x	x	NOUN
admet-24	35	7	-	-	NOUN
admet-24	35	8	ray	ray	NOUN
admet-24	35	9	powder	powder	NOUN
admet-24	35	10	diffraction	diffraction	NOUN
admet-24	35	11	and	and	CCONJ
admet-24	35	12	polarization	polarization	NOUN
admet-24	35	13	light	light	NOUN
admet-24	35	14	microscopy	microscopy	NOUN
admet-24	35	15	.	.	PUNCT
admet-24	36	1	the	the	DET
admet-24	36	2	ionic	ionic	ADJ
admet-24	36	3	strength	strength	NOUN
admet-24	36	4	in	in	ADP
admet-24	36	5	the	the	DET
admet-24	36	6	studied	study	VERB
admet-24	36	7	systems	system	NOUN
admet-24	36	8	ranged	range	VERB
admet-24	36	9	from	from	ADP
admet-24	36	10	0.25	0.25	NUM
admet-24	36	11	to	to	ADP
admet-24	36	12	4.3	4.3	NUM
admet-24	36	13	m.	m.	NOUN
admet-24	36	14	experimental	experimental	ADJ
admet-24	36	15	chemicals	chemical	NOUN
admet-24	36	16	codeine	codeine	PROPN
admet-24	36	17	hydrochloride	hydrochloride	NOUN
admet-24	36	18	,	,	PUNCT
admet-24	36	19	codeine	codeine	NOUN
admet-24	36	20	phosphate	phosphate	NOUN
admet-24	36	21	,	,	PUNCT
admet-24	36	22	lidocaine	lidocaine	NOUN
admet-24	36	23	free	free	ADJ
admet-24	36	24	base	base	NOUN
admet-24	36	25	and	and	CCONJ
admet-24	36	26	lidocaine	lidocaine	NOUN
admet-24	36	27	hydrochloride	hydrochloride	NOUN
admet-24	36	28	were	be	AUX
admet-24	36	29	purchased	purchase	VERB
admet-24	36	30	from	from	ADP
admet-24	36	31	sigma	sigma	NOUN
admet-24	36	32	and	and	CCONJ
admet-24	36	33	used	use	VERB
admet-24	36	34	without	without	ADP
admet-24	36	35	further	further	ADJ
admet-24	36	36	purification	purification	NOUN
admet-24	36	37	.	.	PUNCT
admet-24	37	1	diprenorphine	diprenorphine	NOUN
admet-24	37	2	hydrochloride	hydrochloride	NOUN
admet-24	37	3	was	be	AUX
admet-24	37	4	an	an	DET
admet-24	37	5	in	in	ADP
admet-24	37	6	-	-	PUNCT
admet-24	37	7	house	house	NOUN
admet-24	37	8	synthesized	synthesize	VERB
admet-24	37	9	compound	compound	NOUN
admet-24	37	10	and	and	CCONJ
admet-24	37	11	was	be	AUX
admet-24	37	12	of	of	ADP
admet-24	37	13	analytical	analytical	ADJ
admet-24	37	14	grade	grade	NOUN
admet-24	37	15	.	.	PUNCT
admet-24	38	1	gergely	gergely	ADV
admet-24	38	2	völgyi	völgyi	VERB
admet-24	38	3	et	et	PROPN
admet-24	38	4	al	al	PROPN
admet-24	38	5	.	.	PROPN
admet-24	38	6	admet	admet	PROPN
admet-24	38	7	&	&	CCONJ
admet-24	38	8	dmpk	dmpk	PROPN
admet-24	38	9	1(4	1(4	NUM
admet-24	38	10	)	)	PUNCT
admet-24	38	11	(	(	PUNCT
admet-24	38	12	2013	2013	NUM
admet-24	38	13	)	)	PUNCT
admet-24	38	14	48	48	NUM
admet-24	38	15	-	-	SYM
admet-24	38	16	62	62	NUM
admet-24	38	17	50	50	NUM
admet-24	38	18	potassium	potassium	NOUN
admet-24	38	19	hydroxide	hydroxide	NOUN
admet-24	38	20	and	and	CCONJ
admet-24	38	21	hydrochloric	hydrochloric	ADJ
admet-24	38	22	acid	acid	NOUN
admet-24	38	23	used	use	VERB
admet-24	38	24	for	for	ADP
admet-24	38	25	pka	pka	PROPN
admet-24	38	26	determination	determination	NOUN
admet-24	38	27	were	be	AUX
admet-24	38	28	from	from	ADP
admet-24	38	29	sigma	sigma	PROPN
admet-24	38	30	.	.	PUNCT
admet-24	39	1	the	the	DET
admet-24	39	2	koh	koh	PROPN
admet-24	39	3	titrant	titrant	NOUN
admet-24	39	4	solution	solution	NOUN
admet-24	39	5	was	be	AUX
admet-24	39	6	standardized	standardize	VERB
admet-24	39	7	by	by	ADP
admet-24	39	8	titration	titration	NOUN
admet-24	39	9	against	against	ADP
admet-24	39	10	primary	primary	ADJ
admet-24	39	11	standards	standard	NOUN
admet-24	39	12	potassium	potassium	NOUN
admet-24	39	13	hydrogen	hydrogen	NOUN
admet-24	39	14	phthalate	phthalate	NOUN
admet-24	39	15	dissolved	dissolve	VERB
admet-24	39	16	in	in	ADP
admet-24	39	17	15	15	NUM
admet-24	39	18	ml	ml	NOUN
admet-24	39	19	of	of	ADP
admet-24	39	20	0.15	0.15	NUM
admet-24	39	21	m	m	NOUN
admet-24	39	22	potassium	potassium	NOUN
admet-24	39	23	chloride	chloride	NOUN
admet-24	39	24	.	.	PUNCT
admet-24	40	1	potassium	potassium	NOUN
admet-24	40	2	hydrogen	hydrogen	NOUN
admet-24	40	3	phthalate	phthalate	NOUN
admet-24	40	4	and	and	CCONJ
admet-24	40	5	potassium	potassium	NOUN
admet-24	40	6	chloride	chloride	NOUN
admet-24	40	7	were	be	AUX
admet-24	40	8	of	of	ADP
admet-24	40	9	analytical	analytical	ADJ
admet-24	40	10	grade	grade	NOUN
admet-24	40	11	and	and	CCONJ
admet-24	40	12	were	be	AUX
admet-24	40	13	purchased	purchase	VERB
admet-24	40	14	from	from	ADP
admet-24	40	15	sigma	sigma	PROPN
admet-24	40	16	.	.	PUNCT
admet-24	41	1	the	the	DET
admet-24	41	2	hcl	hcl	PROPN
admet-24	41	3	titrant	titrant	NOUN
admet-24	41	4	solution	solution	NOUN
admet-24	41	5	was	be	AUX
admet-24	41	6	standardized	standardize	VERB
admet-24	41	7	by	by	ADP
admet-24	41	8	titrating	titrate	VERB
admet-24	41	9	a	a	DET
admet-24	41	10	measured	measured	ADJ
admet-24	41	11	volume	volume	NOUN
admet-24	41	12	against	against	ADP
admet-24	41	13	the	the	DET
admet-24	41	14	standardized	standardized	ADJ
admet-24	41	15	koh	koh	PROPN
admet-24	41	16	.	.	PUNCT
admet-24	42	1	two	two	NUM
admet-24	42	2	buffer	buffer	NOUN
admet-24	42	3	solutions	solution	NOUN
admet-24	42	4	(	(	PUNCT
admet-24	42	5	britton	britton	PROPN
admet-24	42	6	–	–	PUNCT
admet-24	42	7	robinson	robinson	PROPN
admet-24	42	8	universal	universal	ADJ
admet-24	42	9	and	and	CCONJ
admet-24	42	10	sörensen	sörensen	ADJ
admet-24	42	11	phosphate	phosphate	NOUN
admet-24	42	12	)	)	PUNCT
admet-24	42	13	were	be	AUX
admet-24	42	14	used	use	VERB
admet-24	42	15	at	at	ADP
admet-24	42	16	ph	ph	PROPN
admet-24	42	17	5	5	NUM
admet-24	42	18	in	in	ADP
admet-24	42	19	the	the	DET
admet-24	42	20	shake	shake	NOUN
admet-24	42	21	-	-	PUNCT
admet-24	42	22	flask	flask	NOUN
admet-24	42	23	experiments	experiment	NOUN
admet-24	42	24	of	of	ADP
admet-24	42	25	codeine	codeine	NOUN
admet-24	42	26	and	and	CCONJ
admet-24	42	27	lidocaine	lidocaine	NOUN
admet-24	42	28	.	.	PUNCT
admet-24	43	1	britton	britton	PROPN
admet-24	43	2	-	-	PUNCT
admet-24	43	3	robinson	robinson	PROPN
admet-24	43	4	buffer	buffer	NOUN
admet-24	43	5	solution	solution	NOUN
admet-24	43	6	(	(	PUNCT
admet-24	43	7	mixture	mixture	NOUN
admet-24	43	8	of	of	ADP
admet-24	43	9	acetic	acetic	ADJ
admet-24	43	10	,	,	PUNCT
admet-24	43	11	phosphoric	phosphoric	NOUN
admet-24	43	12	and	and	CCONJ
admet-24	43	13	boric	boric	ADJ
admet-24	43	14	acids	acid	NOUN
admet-24	43	15	,	,	PUNCT
admet-24	43	16	each	each	PRON
admet-24	43	17	at	at	ADP
admet-24	43	18	0.04	0.04	NUM
admet-24	43	19	m	m	NOUN
admet-24	43	20	)	)	PUNCT
admet-24	43	21	was	be	AUX
admet-24	43	22	treated	treat	VERB
admet-24	43	23	with	with	ADP
admet-24	43	24	0.2	0.2	NUM
admet-24	43	25	m	m	PROPN
admet-24	43	26	naoh	naoh	NOUN
admet-24	43	27	to	to	PART
admet-24	43	28	give	give	VERB
admet-24	43	29	the	the	DET
admet-24	43	30	required	require	VERB
admet-24	43	31	ph	ph	NOUN
admet-24	43	32	.	.	PUNCT
admet-24	44	1	the	the	DET
admet-24	44	2	sörensen	sörensen	NOUN
admet-24	44	3	phosphate	phosphate	NOUN
admet-24	44	4	buffer	buffer	NOUN
admet-24	44	5	solutions	solution	NOUN
admet-24	44	6	were	be	AUX
admet-24	44	7	prepared	prepare	VERB
admet-24	44	8	by	by	ADP
admet-24	44	9	mixing	mix	VERB
admet-24	44	10	0.067	0.067	NUM
admet-24	44	11	m	m	NOUN
admet-24	44	12	na2hpo4	na2hpo4	PROPN
admet-24	44	13	and	and	CCONJ
admet-24	44	14	0.067	0.067	NUM
admet-24	44	15	m	m	PROPN
admet-24	44	16	kh2po4	kh2po4	NOUN
admet-24	44	17	solutions	solution	NOUN
admet-24	44	18	to	to	PART
admet-24	44	19	reach	reach	VERB
admet-24	44	20	the	the	DET
admet-24	44	21	required	require	VERB
admet-24	44	22	ph	ph	NOUN
admet-24	44	23	(	(	PUNCT
admet-24	44	24	4.8	4.8	NUM
admet-24	44	25	–	–	SYM
admet-24	44	26	8.5	8.5	NUM
admet-24	44	27	)	)	PUNCT
admet-24	44	28	.	.	PUNCT
admet-24	45	1	phosphate	phosphate	NOUN
admet-24	45	2	-	-	PUNCT
admet-24	45	3	containing	contain	VERB
admet-24	45	4	solutions	solution	NOUN
admet-24	45	5	between	between	ADP
admet-24	45	6	ph	ph	PROPN
admet-24	45	7	1	1	NUM
admet-24	45	8	and	and	CCONJ
admet-24	45	9	12.5	12.5	NUM
admet-24	45	10	were	be	AUX
admet-24	45	11	used	use	VERB
admet-24	45	12	for	for	ADP
admet-24	45	13	the	the	DET
admet-24	45	14	equilibrium	equilibrium	NOUN
admet-24	45	15	solubility	solubility	NOUN
admet-24	45	16	measurements	measurement	NOUN
admet-24	45	17	of	of	ADP
admet-24	45	18	diprenorphine	diprenorphine	NOUN
admet-24	45	19	,	,	PUNCT
admet-24	45	20	where	where	SCONJ
admet-24	45	21	0.5	0.5	NUM
admet-24	45	22	m	m	NOUN
admet-24	45	23	koh	koh	PROPN
admet-24	45	24	,	,	PUNCT
admet-24	45	25	0.5	0.5	NUM
admet-24	45	26	m	m	NOUN
admet-24	45	27	or	or	CCONJ
admet-24	45	28	14.85	14.85	NUM
admet-24	45	29	m	m	NOUN
admet-24	45	30	h3po4	h3po4	NOUN
admet-24	45	31	(	(	PUNCT
admet-24	45	32	standardized	standardized	ADJ
admet-24	45	33	85	85	NUM
admet-24	45	34	%	%	NOUN
admet-24	45	35	)	)	PUNCT
admet-24	45	36	solutions	solution	NOUN
admet-24	45	37	were	be	AUX
admet-24	45	38	used	use	VERB
admet-24	45	39	to	to	PART
admet-24	45	40	reach	reach	VERB
admet-24	45	41	the	the	DET
admet-24	45	42	desired	desire	VERB
admet-24	45	43	ph	ph	ADJ
admet-24	45	44	values	value	NOUN
admet-24	45	45	.	.	PUNCT
admet-24	46	1	distilled	distil	VERB
admet-24	46	2	water	water	NOUN
admet-24	46	3	of	of	ADP
admet-24	46	4	ph	ph	PROPN
admet-24	46	5	.	.	PROPN
admet-24	46	6	eur	eur	PROPN
admet-24	46	7	.	.	PUNCT
admet-24	47	1	grade	grade	NOUN
admet-24	47	2	was	be	AUX
admet-24	47	3	used	use	VERB
admet-24	47	4	.	.	PUNCT
admet-24	48	1	all	all	DET
admet-24	48	2	other	other	ADJ
admet-24	48	3	reagents	reagent	NOUN
admet-24	48	4	were	be	AUX
admet-24	48	5	of	of	ADP
admet-24	48	6	analytical	analytical	ADJ
admet-24	48	7	grade	grade	NOUN
admet-24	48	8	.	.	PUNCT
admet-24	49	1	ph	ph	ADJ
admet-24	49	2	electrode	electrode	NOUN
admet-24	49	3	standardization	standardization	NOUN
admet-24	49	4	and	and	CCONJ
admet-24	49	5	compensation	compensation	NOUN
admet-24	49	6	for	for	ADP
admet-24	49	7	large	large	ADJ
admet-24	49	8	changes	change	NOUN
admet-24	49	9	in	in	ADP
admet-24	49	10	ionic	ionic	ADJ
admet-24	49	11	strength	strength	NOUN
admet-24	49	12	all	all	PRON
admet-24	49	13	of	of	ADP
admet-24	49	14	the	the	DET
admet-24	49	15	equilibrium	equilibrium	NOUN
admet-24	49	16	constants	constant	NOUN
admet-24	49	17	reported	report	VERB
admet-24	49	18	here	here	ADV
admet-24	49	19	are	be	AUX
admet-24	49	20	based	base	VERB
admet-24	49	21	on	on	ADP
admet-24	49	22	the	the	DET
admet-24	49	23	concentration	concentration	NOUN
admet-24	49	24	scale	scale	NOUN
admet-24	49	25	,	,	PUNCT
admet-24	49	26	i.e.	i.e.	X
admet-24	49	27	,	,	PUNCT
admet-24	49	28	the	the	DET
admet-24	49	29	“	"	PUNCT
admet-24	49	30	constant	constant	ADJ
admet-24	49	31	ionic	ionic	ADJ
admet-24	49	32	medium	medium	ADJ
admet-24	49	33	”	"	PUNCT
admet-24	49	34	thermodynamic	thermodynamic	ADJ
admet-24	49	35	standard	standard	ADJ
admet-24	49	36	state	state	NOUN
admet-24	49	37	[	[	X
admet-24	49	38	19	19	NUM
admet-24	49	39	]	]	PUNCT
admet-24	49	40	.	.	PUNCT
admet-24	50	1	since	since	SCONJ
admet-24	50	2	the	the	DET
admet-24	50	3	measured	measured	ADJ
admet-24	50	4	ph	ph	NOUN
admet-24	50	5	is	be	AUX
admet-24	50	6	based	base	VERB
admet-24	50	7	on	on	ADP
admet-24	50	8	the	the	DET
admet-24	50	9	operational	operational	ADJ
admet-24	50	10	activity	activity	NOUN
admet-24	50	11	scale	scale	NOUN
admet-24	50	12	,	,	PUNCT
admet-24	50	13	these	these	DET
admet-24	50	14	values	value	NOUN
admet-24	50	15	need	need	VERB
admet-24	50	16	to	to	PART
admet-24	50	17	be	be	AUX
admet-24	50	18	converted	convert	VERB
admet-24	50	19	to	to	ADP
admet-24	50	20	the	the	DET
admet-24	50	21	concentration	concentration	NOUN
admet-24	50	22	scale	scale	NOUN
admet-24	50	23	,	,	PUNCT
admet-24	50	24	pch	pch	ADJ
admet-24	50	25	(=	(=	X
admet-24	50	26	-log[h+	-log[h+	PROPN
admet-24	50	27	]	]	X
admet-24	50	28	)	)	PUNCT
admet-24	50	29	.	.	PUNCT
admet-24	51	1	the	the	DET
admet-24	51	2	procedure	procedure	NOUN
admet-24	51	3	to	to	PART
admet-24	51	4	calibrate	calibrate	VERB
admet-24	51	5	and	and	CCONJ
admet-24	51	6	standardize	standardize	VERB
admet-24	51	7	the	the	DET
admet-24	51	8	ph	ph	ADJ
admet-24	51	9	electrode	electrode	NOUN
admet-24	51	10	is	be	AUX
admet-24	51	11	described	describe	VERB
admet-24	51	12	in	in	ADP
admet-24	51	13	detail	detail	NOUN
admet-24	51	14	elsewhere	elsewhere	ADV
admet-24	51	15	[	[	X
admet-24	51	16	19	19	NUM
admet-24	51	17	]	]	PUNCT
admet-24	51	18	.	.	PUNCT
admet-24	52	1	briefly	briefly	NOUN
admet-24	52	2	,	,	PUNCT
admet-24	52	3	the	the	DET
admet-24	52	4	electrode	electrode	NOUN
admet-24	52	5	is	be	AUX
admet-24	52	6	standardized	standardize	VERB
admet-24	52	7	by	by	ADP
admet-24	52	8	the	the	DET
admet-24	52	9	blank	blank	ADJ
admet-24	52	10	titration	titration	NOUN
admet-24	52	11	method	method	NOUN
admet-24	52	12	:	:	PUNCT
admet-24	52	13	to	to	ADP
admet-24	52	14	a	a	DET
admet-24	52	15	0.15	0.15	NUM
admet-24	52	16	m	m	NOUN
admet-24	52	17	kcl	kcl	NOUN
admet-24	52	18	solution	solution	NOUN
admet-24	52	19	,	,	PUNCT
admet-24	52	20	enough	enough	ADJ
admet-24	52	21	standardized	standardized	ADJ
admet-24	52	22	0.5	0.5	NUM
admet-24	52	23	m	m	NOUN
admet-24	52	24	hcl	hcl	PROPN
admet-24	52	25	is	be	AUX
admet-24	52	26	added	add	VERB
admet-24	52	27	to	to	PART
admet-24	52	28	lower	lower	VERB
admet-24	52	29	the	the	DET
admet-24	52	30	ph	ph	NOUN
admet-24	52	31	to	to	ADP
admet-24	52	32	1.8	1.8	NUM
admet-24	52	33	(	(	PUNCT
admet-24	52	34	0.87	0.87	NUM
admet-24	52	35	±	±	NUM
admet-24	52	36	0.03	0.03	NUM
admet-24	52	37	ml	ml	NOUN
admet-24	52	38	when	when	SCONJ
admet-24	52	39	using	use	VERB
admet-24	52	40	a	a	DET
admet-24	52	41	20	20	NUM
admet-24	52	42	ml	ml	NOUN
admet-24	52	43	solution	solution	NOUN
admet-24	52	44	)	)	PUNCT
admet-24	52	45	;	;	PUNCT
admet-24	52	46	then	then	ADV
admet-24	52	47	the	the	DET
admet-24	52	48	acidified	acidify	VERB
admet-24	52	49	solution	solution	NOUN
admet-24	52	50	is	be	AUX
admet-24	52	51	precisely	precisely	ADV
admet-24	52	52	titrated	titrate	VERB
admet-24	52	53	with	with	ADP
admet-24	52	54	standardized	standardized	ADJ
admet-24	52	55	0.5	0.5	NUM
admet-24	52	56	m	m	NOUN
admet-24	52	57	koh	koh	NOUN
admet-24	52	58	up	up	ADP
admet-24	52	59	to	to	ADP
admet-24	52	60	about	about	ADP
admet-24	52	61	ph	ph	NOUN
admet-24	52	62	12.2	12.2	NUM
admet-24	52	63	(	(	PUNCT
admet-24	52	64	which	which	PRON
admet-24	52	65	consumes	consume	VERB
admet-24	52	66	about	about	ADP
admet-24	52	67	2	2	NUM
admet-24	52	68	ml	ml	ADP
admet-24	52	69	0.5	0.5	NUM
admet-24	52	70	m	m	NOUN
admet-24	52	71	koh	koh	PROPN
admet-24	52	72	)	)	PUNCT
admet-24	52	73	.	.	PUNCT
admet-24	53	1	the	the	DET
admet-24	53	2	blank	blank	PROPN
admet-24	53	3	titration	titration	NOUN
admet-24	53	4	ph	ph	PROPN
admet-24	53	5	data	datum	NOUN
admet-24	53	6	are	be	AUX
admet-24	53	7	fit	fit	ADJ
admet-24	53	8	to	to	ADP
admet-24	53	9	a	a	DET
admet-24	53	10	four	four	NUM
admet-24	53	11	-	-	PUNCT
admet-24	53	12	parameter	parameter	NOUN
admet-24	53	13	equation	equation	NOUN
admet-24	53	14	[	[	X
admet-24	53	15	20	20	NUM
admet-24	53	16	]	]	SYM
admet-24	53	17	:	:	PUNCT
admet-24	53	18	ph	ph	PROPN
admet-24	53	19	=	=	PUNCT
admet-24	53	20	α	α	PROPN
admet-24	54	1	+	+	PROPN
admet-24	54	2	ks	ks	PROPN
admet-24	54	3	pch	pch	PROPN
admet-24	54	4	+	+	CCONJ
admet-24	54	5	jh	jh	PROPN
admet-24	55	1	[	[	X
admet-24	55	2	h	h	NOUN
admet-24	55	3	+	+	X
admet-24	55	4	]	]	PUNCT
admet-24	56	1	+	+	CCONJ
admet-24	56	2	joh	joh	PROPN
admet-24	56	3	kw/[h	kw/[h	PROPN
admet-24	56	4	+	+	CCONJ
admet-24	56	5	]	]	PUNCT
admet-24	56	6	(	(	PUNCT
admet-24	56	7	1	1	X
admet-24	56	8	)	)	PUNCT
admet-24	56	9	where	where	SCONJ
admet-24	56	10	kw	kw	PROPN
admet-24	56	11	is	be	AUX
admet-24	56	12	the	the	DET
admet-24	56	13	ionization	ionization	NOUN
admet-24	56	14	constant	constant	ADJ
admet-24	56	15	of	of	ADP
admet-24	56	16	water	water	NOUN
admet-24	56	17	.	.	PUNCT
admet-24	57	1	the	the	DET
admet-24	57	2	jh	jh	PROPN
admet-24	57	3	term	term	NOUN
admet-24	57	4	corrects	correct	VERB
admet-24	57	5	ph	ph	ADJ
admet-24	57	6	readings	reading	NOUN
admet-24	57	7	for	for	ADP
admet-24	57	8	the	the	DET
admet-24	57	9	nonlinear	nonlinear	ADJ
admet-24	57	10	ph	ph	ADJ
admet-24	57	11	response	response	NOUN
admet-24	57	12	due	due	ADP
admet-24	57	13	to	to	ADP
admet-24	57	14	liquid	liquid	ADJ
admet-24	57	15	junction	junction	NOUN
admet-24	57	16	and	and	CCONJ
admet-24	57	17	asymmetry	asymmetry	NOUN
admet-24	57	18	potentials	potential	NOUN
admet-24	57	19	in	in	ADP
admet-24	57	20	highly	highly	ADV
admet-24	57	21	acidic	acidic	ADJ
admet-24	57	22	solutions	solution	NOUN
admet-24	57	23	(	(	PUNCT
admet-24	57	24	ph	ph	X
admet-24	57	25	<	<	X
admet-24	57	26	2	2	NUM
admet-24	57	27	)	)	PUNCT
admet-24	57	28	,	,	PUNCT
admet-24	57	29	while	while	SCONJ
admet-24	57	30	the	the	DET
admet-24	57	31	joh	joh	PROPN
admet-24	57	32	term	term	NOUN
admet-24	57	33	corrects	correct	NOUN
admet-24	57	34	for	for	ADP
admet-24	57	35	high	high	ADJ
admet-24	57	36	-	-	PUNCT
admet-24	57	37	ph	ph	NOUN
admet-24	57	38	nonlinear	nonlinear	ADJ
admet-24	57	39	effects	effect	NOUN
admet-24	57	40	[	[	X
admet-24	57	41	19	19	NUM
admet-24	57	42	]	]	PUNCT
admet-24	57	43	.	.	PUNCT
admet-24	58	1	typical	typical	ADJ
admet-24	58	2	values	value	NOUN
admet-24	58	3	of	of	ADP
admet-24	58	4	the	the	DET
admet-24	58	5	adjustable	adjustable	ADJ
admet-24	58	6	parameters	parameter	NOUN
admet-24	58	7	at	at	ADP
admet-24	58	8	25c	25c	NUM
admet-24	58	9	and	and	CCONJ
admet-24	58	10	0.15	0.15	NUM
admet-24	58	11	m	m	PROPN
admet-24	58	12	ionic	ionic	ADJ
admet-24	58	13	strength	strength	NOUN
admet-24	58	14	are	be	AUX
admet-24	58	15	α	α	NOUN
admet-24	58	16	=	=	SYM
admet-24	58	17	0.09	0.09	NUM
admet-24	58	18	,	,	PUNCT
admet-24	58	19	ks	ks	NOUN
admet-24	58	20	=	=	NOUN
admet-24	58	21	1.002	1.002	NUM
admet-24	58	22	,	,	PUNCT
admet-24	58	23	jh	jh	PROPN
admet-24	58	24	=	=	SYM
admet-24	58	25	0.5	0.5	NUM
admet-24	58	26	and	and	CCONJ
admet-24	58	27	joh	joh	PROPN
admet-24	58	28	=	=	PROPN
admet-24	58	29	-0.5	-0.5	PROPN
admet-24	58	30	.	.	PUNCT
admet-24	59	1	however	however	ADV
admet-24	59	2	,	,	PUNCT
admet-24	59	3	each	each	DET
admet-24	59	4	electrode	electrode	NOUN
admet-24	59	5	indicates	indicate	VERB
admet-24	59	6	its	its	PRON
admet-24	59	7	own	own	ADJ
admet-24	59	8	characteristic	characteristic	ADJ
admet-24	59	9	set	set	NOUN
admet-24	59	10	.	.	PUNCT
admet-24	60	1	since	since	SCONJ
admet-24	60	2	salt	salt	NOUN
admet-24	60	3	solubility	solubility	NOUN
admet-24	60	4	measurements	measurement	NOUN
admet-24	60	5	can	can	AUX
admet-24	60	6	be	be	AUX
admet-24	60	7	under	under	ADP
admet-24	60	8	conditions	condition	NOUN
admet-24	60	9	where	where	SCONJ
admet-24	60	10	ionic	ionic	ADJ
admet-24	60	11	strength	strength	NOUN
admet-24	60	12	may	may	AUX
admet-24	60	13	reach	reach	VERB
admet-24	60	14	values	value	NOUN
admet-24	60	15	as	as	ADV
admet-24	60	16	high	high	ADJ
admet-24	60	17	as	as	ADP
admet-24	60	18	1	1	NUM
admet-24	60	19	m	m	NOUN
admet-24	60	20	,	,	PUNCT
admet-24	60	21	the	the	DET
admet-24	60	22	experimentally	experimentally	ADV
admet-24	60	23	-	-	PUNCT
admet-24	60	24	determined	determine	VERB
admet-24	60	25	parameters	parameter	NOUN
admet-24	60	26	in	in	ADP
admet-24	60	27	eq	eq	ADP
admet-24	60	28	.	.	PUNCT
admet-24	61	1	(	(	PUNCT
admet-24	61	2	1	1	NUM
admet-24	61	3	)	)	PUNCT
admet-24	61	4	,	,	PUNCT
admet-24	61	5	based	base	VERB
admet-24	61	6	on	on	ADP
admet-24	61	7	the	the	DET
admet-24	61	8	“	"	PUNCT
admet-24	61	9	reference	reference	NOUN
admet-24	61	10	”	"	PUNCT
admet-24	61	11	ionic	ionic	ADJ
admet-24	61	12	strength	strength	NOUN
admet-24	61	13	0.15	0.15	NUM
admet-24	61	14	m	m	NOUN
admet-24	61	15	,	,	PUNCT
admet-24	61	16	are	be	AUX
admet-24	61	17	automatically	automatically	ADV
admet-24	61	18	compensated	compensate	VERB
admet-24	61	19	by	by	ADP
admet-24	61	20	the	the	DET
admet-24	61	21	computational	computational	ADJ
admet-24	61	22	procedure	procedure	NOUN
admet-24	61	23	in	in	ADP
admet-24	61	24	pdisol	pdisol	ADJ
admet-24	61	25	-	-	PUNCT
admet-24	61	26	x	x	NOUN
admet-24	61	27	,	,	PUNCT
admet-24	61	28	for	for	SCONJ
admet-24	61	29	changes	change	NOUN
admet-24	61	30	in	in	ADP
admet-24	61	31	ionic	ionic	ADJ
admet-24	61	32	strength	strength	NOUN
admet-24	61	33	from	from	ADP
admet-24	61	34	the	the	DET
admet-24	61	35	reference	reference	NOUN
admet-24	61	36	value	value	NOUN
admet-24	61	37	0.15	0.15	NUM
admet-24	61	38	m	m	NOUN
admet-24	61	39	to	to	ADP
admet-24	61	40	the	the	DET
admet-24	61	41	actual	actual	ADJ
admet-24	61	42	values	value	NOUN
admet-24	61	43	in	in	ADP
admet-24	61	44	a	a	DET
admet-24	61	45	particular	particular	ADJ
admet-24	61	46	solubility	solubility	NOUN
admet-24	61	47	assay	assay	VERB
admet-24	61	48	,	,	PUNCT
admet-24	61	49	according	accord	VERB
admet-24	61	50	to	to	ADP
admet-24	61	51	the	the	DET
admet-24	61	52	empirically	empirically	ADV
admet-24	61	53	-	-	PUNCT
admet-24	61	54	determined	determine	VERB
admet-24	61	55	relationships	relationship	NOUN
admet-24	61	56	defined	define	VERB
admet-24	61	57	elsewhere	elsewhere	ADV
admet-24	61	58	[	[	X
admet-24	61	59	19	19	NUM
admet-24	61	60	]	]	PUNCT
admet-24	61	61	.	.	PUNCT
admet-24	62	1	pka	pka	PROPN
admet-24	62	2	determination	determination	NOUN
admet-24	62	3	the	the	DET
admet-24	62	4	pka	pka	PROPN
admet-24	62	5	values	value	NOUN
admet-24	62	6	of	of	ADP
admet-24	62	7	diprenorphine	diprenorphine	NOUN
admet-24	62	8	were	be	AUX
admet-24	62	9	determined	determine	VERB
admet-24	62	10	by	by	ADP
admet-24	62	11	potentiometry	potentiometry	NOUN
admet-24	62	12	using	use	VERB
admet-24	62	13	a	a	DET
admet-24	62	14	glpka	glpka	NOUN
admet-24	62	15	instrument	instrument	NOUN
admet-24	62	16	(	(	PUNCT
admet-24	62	17	sirius	sirius	PROPN
admet-24	62	18	,	,	PUNCT
admet-24	62	19	forest	forest	NOUN
admet-24	62	20	row	row	NOUN
admet-24	62	21	,	,	PUNCT
admet-24	62	22	uk	uk	PROPN
admet-24	62	23	)	)	PUNCT
admet-24	62	24	equipped	equip	VERB
admet-24	62	25	with	with	ADP
admet-24	62	26	a	a	DET
admet-24	62	27	combination	combination	NOUN
admet-24	62	28	ag	ag	NOUN
admet-24	62	29	/	/	SYM
admet-24	62	30	agcl	agcl	ADJ
admet-24	62	31	ph	ph	NOUN
admet-24	62	32	electrode	electrode	NOUN
admet-24	62	33	.	.	PUNCT
admet-24	63	1	the	the	DET
admet-24	63	2	titrations	titration	NOUN
admet-24	63	3	were	be	AUX
admet-24	63	4	carried	carry	VERB
admet-24	63	5	out	out	ADP
admet-24	63	6	at	at	ADP
admet-24	63	7	constant	constant	ADJ
admet-24	63	8	ionic	ionic	ADJ
admet-24	63	9	strength	strength	NOUN
admet-24	63	10	(	(	PUNCT
admet-24	63	11	i	i	NOUN
admet-24	63	12	=	=	NOUN
admet-24	63	13	0.15	0.15	NUM
admet-24	63	14	m	m	NOUN
admet-24	63	15	kcl	kcl	NOUN
admet-24	63	16	)	)	PUNCT
admet-24	63	17	and	and	CCONJ
admet-24	63	18	temperature	temperature	NOUN
admet-24	63	19	(	(	PUNCT
admet-24	63	20	t	t	NOUN
admet-24	63	21	=	=	SYM
admet-24	63	22	25.0	25.0	NUM
admet-24	63	23	±	±	NUM
admet-24	63	24	0.5	0.5	NUM
admet-24	63	25	°	°	ADP
admet-24	63	26	c	c	NOUN
admet-24	63	27	)	)	PUNCT
admet-24	63	28	,	,	PUNCT
admet-24	63	29	and	and	CCONJ
admet-24	63	30	under	under	ADP
admet-24	63	31	nitrogen	nitrogen	NOUN
admet-24	63	32	atmosphere	atmosphere	NOUN
admet-24	63	33	.	.	PUNCT
admet-24	64	1	aqueous	aqueous	ADJ
admet-24	64	2	solutions	solution	NOUN
admet-24	64	3	of	of	ADP
admet-24	64	4	diprenorphine	diprenorphine	NOUN
admet-24	64	5	hydrochloride	hydrochloride	NOUN
admet-24	64	6	(	(	PUNCT
admet-24	64	7	10	10	NUM
admet-24	64	8	ml	ml	NOUN
admet-24	64	9	,	,	PUNCT
admet-24	64	10	0.7	0.7	NUM
admet-24	64	11	-	-	SYM
admet-24	64	12	0.8	0.8	NUM
admet-24	64	13	mm	mm	NOUN
admet-24	64	14	)	)	PUNCT
admet-24	64	15	were	be	AUX
admet-24	64	16	pre	pre	ADJ
admet-24	64	17	-	-	ADJ
admet-24	64	18	acidified	acidified	ADJ
admet-24	64	19	to	to	ADP
admet-24	64	20	admet	admet	PROPN
admet-24	64	21	&	&	CCONJ
admet-24	64	22	dmpk	dmpk	PROPN
admet-24	64	23	1(4	1(4	NUM
admet-24	64	24	)	)	PUNCT
admet-24	64	25	(	(	PUNCT
admet-24	64	26	2013	2013	NUM
admet-24	64	27	)	)	PUNCT
admet-24	64	28	48	48	NUM
admet-24	64	29	-	-	SYM
admet-24	64	30	62	62	NUM
admet-24	64	31	novel	novel	NOUN
admet-24	64	32	method	method	NOUN
admet-24	64	33	of	of	ADP
admet-24	64	34	salt	salt	NOUN
admet-24	64	35	solubility	solubility	NOUN
admet-24	64	36	analysis	analysis	NOUN
admet-24	64	37	doi	doi	NOUN
admet-24	64	38	:	:	PUNCT
admet-24	64	39	10.5599	10.5599	NUM
admet-24	64	40	/	/	SYM
admet-24	64	41	admet.1.4.24	admet.1.4.24	PROPN
admet-24	64	42	51	51	NUM
admet-24	64	43	ph	ph	NOUN
admet-24	64	44	2	2	NUM
admet-24	64	45	with	with	ADP
admet-24	64	46	0.5	0.5	NUM
admet-24	64	47	m	m	NOUN
admet-24	64	48	hcl	hcl	PROPN
admet-24	64	49	,	,	PUNCT
admet-24	64	50	and	and	CCONJ
admet-24	64	51	then	then	ADV
admet-24	64	52	titrated	titrate	VERB
admet-24	64	53	with	with	ADP
admet-24	64	54	0.5	0.5	NUM
admet-24	64	55	m	m	NOUN
admet-24	64	56	koh	koh	NOUN
admet-24	64	57	to	to	ADP
admet-24	64	58	ph	ph	PROPN
admet-24	64	59	12	12	NUM
admet-24	64	60	.	.	PUNCT
admet-24	65	1	three	three	NUM
admet-24	65	2	parallel	parallel	ADJ
admet-24	65	3	measurements	measurement	NOUN
admet-24	65	4	were	be	AUX
admet-24	65	5	carried	carry	VERB
admet-24	65	6	out	out	ADP
admet-24	65	7	.	.	PUNCT
admet-24	66	1	the	the	DET
admet-24	66	2	pka	pka	PROPN
admet-24	66	3	values	value	NOUN
admet-24	66	4	were	be	AUX
admet-24	66	5	calculated	calculate	VERB
admet-24	66	6	by	by	ADP
admet-24	66	7	the	the	DET
admet-24	66	8	refinementpro	refinementpro	ADJ
admet-24	66	9	tm	tm	PROPN
admet-24	66	10	software	software	PROPN
admet-24	66	11	(	(	PUNCT
admet-24	66	12	sirius	sirius	PROPN
admet-24	66	13	,	,	PUNCT
admet-24	66	14	forest	forest	NOUN
admet-24	66	15	row	row	NOUN
admet-24	66	16	,	,	PUNCT
admet-24	66	17	uk	uk	PROPN
admet-24	66	18	)	)	PUNCT
admet-24	66	19	.	.	PUNCT
admet-24	67	1	solubility	solubility	NOUN
admet-24	67	2	measurements	measurement	NOUN
admet-24	67	3	by	by	ADP
admet-24	67	4	saturation	saturation	NOUN
admet-24	67	5	shake	shake	NOUN
admet-24	67	6	-	-	PUNCT
admet-24	67	7	flask	flask	NOUN
admet-24	67	8	method	method	NOUN
admet-24	67	9	in	in	ADP
admet-24	67	10	the	the	DET
admet-24	67	11	shake	shake	NOUN
admet-24	67	12	-	-	PUNCT
admet-24	67	13	flask	flask	NOUN
admet-24	67	14	experiments	experiment	NOUN
admet-24	67	15	,	,	PUNCT
admet-24	67	16	the	the	DET
admet-24	67	17	ph	ph	NOUN
admet-24	67	18	of	of	ADP
admet-24	67	19	the	the	DET
admet-24	67	20	solutions	solution	NOUN
admet-24	67	21	was	be	AUX
admet-24	67	22	measured	measure	VERB
admet-24	67	23	by	by	ADP
admet-24	67	24	a	a	DET
admet-24	67	25	radiometer	radiometer	NOUN
admet-24	67	26	phm	phm	NOUN
admet-24	67	27	220	220	NUM
admet-24	67	28	ph	ph	NOUN
admet-24	67	29	meter	meter	NOUN
admet-24	67	30	with	with	ADP
admet-24	67	31	combined	combined	ADJ
admet-24	67	32	ag	ag	PROPN
admet-24	67	33	/	/	SYM
admet-24	67	34	agcl	agcl	NOUN
admet-24	67	35	glass	glass	NOUN
admet-24	67	36	electrode	electrode	NOUN
admet-24	67	37	.	.	PUNCT
admet-24	68	1	the	the	DET
admet-24	68	2	temperature	temperature	NOUN
admet-24	68	3	of	of	ADP
admet-24	68	4	the	the	DET
admet-24	68	5	samples	sample	NOUN
admet-24	68	6	was	be	AUX
admet-24	68	7	maintained	maintain	VERB
admet-24	68	8	at	at	ADP
admet-24	68	9	25.0	25.0	NUM
admet-24	68	10	±	±	NUM
admet-24	68	11	0.5	0.5	NUM
admet-24	68	12	°	°	ADP
admet-24	68	13	c	c	NOUN
admet-24	68	14	during	during	ADP
admet-24	68	15	the	the	DET
admet-24	68	16	solubility	solubility	NOUN
admet-24	68	17	measurements	measurement	NOUN
admet-24	68	18	using	use	VERB
admet-24	68	19	a	a	DET
admet-24	68	20	lauda	lauda	NOUN
admet-24	68	21	thermostat	thermostat	NOUN
admet-24	68	22	.	.	PUNCT
admet-24	69	1	a	a	DET
admet-24	69	2	heidolph	heidolph	NOUN
admet-24	69	3	mr	mr	PROPN
admet-24	69	4	1000	1000	NUM
admet-24	69	5	magnetic	magnetic	ADJ
admet-24	69	6	stirrer	stirrer	NOUN
admet-24	69	7	was	be	AUX
admet-24	69	8	used	use	VERB
admet-24	69	9	to	to	PART
admet-24	69	10	mix	mix	VERB
admet-24	69	11	the	the	DET
admet-24	69	12	two	two	NUM
admet-24	69	13	phases	phase	NOUN
admet-24	69	14	.	.	PUNCT
admet-24	70	1	the	the	DET
admet-24	70	2	concentration	concentration	NOUN
admet-24	70	3	in	in	ADP
admet-24	70	4	the	the	DET
admet-24	70	5	supernatant	supernatant	NOUN
admet-24	70	6	was	be	AUX
admet-24	70	7	measured	measure	VERB
admet-24	70	8	by	by	ADP
admet-24	70	9	spectroscopy	spectroscopy	NOUN
admet-24	70	10	using	use	VERB
admet-24	70	11	a	a	DET
admet-24	70	12	jasco	jasco	PROPN
admet-24	70	13	v-550	v-550	PROPN
admet-24	70	14	uv	uv	NOUN
admet-24	70	15	/	/	SYM
admet-24	70	16	vis	vis	X
admet-24	70	17	spectrophotometer	spectrophotometer	NOUN
admet-24	70	18	.	.	PUNCT
admet-24	71	1	to	to	PART
admet-24	71	2	facilitate	facilitate	VERB
admet-24	71	3	the	the	DET
admet-24	71	4	measure	measure	NOUN
admet-24	71	5	of	of	ADP
admet-24	71	6	concentration	concentration	NOUN
admet-24	71	7	by	by	ADP
admet-24	71	8	uv	uv	NOUN
admet-24	71	9	spectrophotometry	spectrophotometry	NOUN
admet-24	71	10	,	,	PUNCT
admet-24	71	11	the	the	DET
admet-24	71	12	specific	specific	ADJ
admet-24	71	13	absorbance	absorbance	NOUN
admet-24	71	14	(	(	PUNCT
admet-24	71	15	a1	a1	NOUN
admet-24	71	16	cm	cm	NOUN
admet-24	71	17	1	1	NUM
admet-24	71	18	%	%	NOUN
admet-24	71	19	,	,	PUNCT
admet-24	71	20	the	the	DET
admet-24	71	21	absorbance	absorbance	NOUN
admet-24	71	22	of	of	ADP
admet-24	71	23	1	1	NUM
admet-24	71	24	g/100	g/100	NOUN
admet-24	71	25	ml	ml	NOUN
admet-24	71	26	solution	solution	NOUN
admet-24	71	27	over	over	ADP
admet-24	71	28	a	a	DET
admet-24	71	29	1	1	NUM
admet-24	71	30	cm	cm	NOUN
admet-24	71	31	optical	optical	ADJ
admet-24	71	32	path	path	NOUN
admet-24	71	33	length	length	NOUN
admet-24	71	34	at	at	ADP
admet-24	71	35	a	a	DET
admet-24	71	36	given	give	VERB
admet-24	71	37	wavelength	wavelength	NOUN
admet-24	71	38	)	)	PUNCT
admet-24	71	39	of	of	ADP
admet-24	71	40	each	each	DET
admet-24	71	41	sample	sample	NOUN
admet-24	71	42	at	at	ADP
admet-24	71	43	the	the	DET
admet-24	71	44	given	give	VERB
admet-24	71	45	ph	ph	ADJ
admet-24	71	46	values	value	NOUN
admet-24	71	47	was	be	AUX
admet-24	71	48	determined	determine	VERB
admet-24	71	49	separately	separately	ADV
admet-24	71	50	at	at	ADP
admet-24	71	51	a	a	DET
admet-24	71	52	selected	select	VERB
admet-24	71	53	wavelength	wavelength	NOUN
admet-24	71	54	using	use	VERB
admet-24	71	55	12	12	NUM
admet-24	71	56	-	-	SYM
admet-24	71	57	18	18	NUM
admet-24	71	58	points	point	NOUN
admet-24	71	59	of	of	ADP
admet-24	71	60	a	a	DET
admet-24	71	61	minimum	minimum	NOUN
admet-24	71	62	of	of	ADP
admet-24	71	63	two	two	NUM
admet-24	71	64	parallel	parallel	ADJ
admet-24	71	65	dilution	dilution	NOUN
admet-24	71	66	series	series	NOUN
admet-24	71	67	,	,	PUNCT
admet-24	71	68	from	from	ADP
admet-24	71	69	the	the	DET
admet-24	71	70	linear	linear	ADJ
admet-24	71	71	regression	regression	NOUN
admet-24	71	72	equation	equation	NOUN
admet-24	71	73	(	(	PUNCT
admet-24	71	74	lambert	lambert	NOUN
admet-24	71	75	-	-	PUNCT
admet-24	71	76	beer	beer	NOUN
admet-24	71	77	law	law	NOUN
admet-24	71	78	)	)	PUNCT
admet-24	71	79	.	.	PUNCT
admet-24	72	1	the	the	DET
admet-24	72	2	equilibrium	equilibrium	NOUN
admet-24	72	3	solubility	solubility	NOUN
admet-24	72	4	of	of	ADP
admet-24	72	5	the	the	DET
admet-24	72	6	samples	sample	NOUN
admet-24	72	7	at	at	ADP
admet-24	72	8	different	different	ADJ
admet-24	72	9	ph	ph	ADJ
admet-24	72	10	values	value	NOUN
admet-24	72	11	was	be	AUX
admet-24	72	12	determined	determine	VERB
admet-24	72	13	by	by	ADP
admet-24	72	14	the	the	DET
admet-24	72	15	new	new	ADJ
admet-24	72	16	protocol	protocol	NOUN
admet-24	72	17	of	of	ADP
admet-24	72	18	saturation	saturation	NOUN
admet-24	72	19	shake	shake	NOUN
admet-24	72	20	-	-	PUNCT
admet-24	72	21	flask	flask	NOUN
admet-24	72	22	method	method	NOUN
admet-24	72	23	[	[	X
admet-24	72	24	21	21	NUM
admet-24	72	25	]	]	PUNCT
admet-24	72	26	.	.	PUNCT
admet-24	73	1	the	the	DET
admet-24	73	2	sample	sample	NOUN
admet-24	73	3	was	be	AUX
admet-24	73	4	added	add	VERB
admet-24	73	5	to	to	ADP
admet-24	73	6	the	the	DET
admet-24	73	7	aqueous	aqueous	ADJ
admet-24	73	8	britton	britton	PROPN
admet-24	73	9	-	-	PUNCT
admet-24	73	10	robinson	robinson	PROPN
admet-24	73	11	universal	universal	ADJ
admet-24	73	12	and	and	CCONJ
admet-24	73	13	sörensen	sörensen	ADJ
admet-24	73	14	phosphate	phosphate	NOUN
admet-24	73	15	buffers	buffer	NOUN
admet-24	73	16	(	(	PUNCT
admet-24	73	17	codeine	codeine	NOUN
admet-24	73	18	and	and	CCONJ
admet-24	73	19	lidocaine	lidocaine	NOUN
admet-24	73	20	)	)	PUNCT
admet-24	73	21	or	or	CCONJ
admet-24	73	22	phosphate	phosphate	NOUN
admet-24	73	23	-	-	PUNCT
admet-24	73	24	containing	contain	VERB
admet-24	73	25	solution	solution	NOUN
admet-24	73	26	(	(	PUNCT
admet-24	73	27	diprenorphine	diprenorphine	NOUN
admet-24	73	28	)	)	PUNCT
admet-24	73	29	until	until	SCONJ
admet-24	73	30	a	a	DET
admet-24	73	31	heterogeneous	heterogeneous	ADJ
admet-24	73	32	system	system	NOUN
admet-24	73	33	(	(	PUNCT
admet-24	73	34	solid	solid	ADJ
admet-24	73	35	sample	sample	NOUN
admet-24	73	36	and	and	CCONJ
admet-24	73	37	liquid	liquid	NOUN
admet-24	73	38	)	)	PUNCT
admet-24	73	39	was	be	AUX
admet-24	73	40	obtained	obtain	VERB
admet-24	73	41	.	.	PUNCT
admet-24	74	1	the	the	DET
admet-24	74	2	solution	solution	NOUN
admet-24	74	3	containing	contain	VERB
admet-24	74	4	solid	solid	ADJ
admet-24	74	5	excess	excess	NOUN
admet-24	74	6	of	of	ADP
admet-24	74	7	the	the	DET
admet-24	74	8	sample	sample	NOUN
admet-24	74	9	was	be	AUX
admet-24	74	10	stirred	stir	VERB
admet-24	74	11	for	for	ADP
admet-24	74	12	a	a	DET
admet-24	74	13	period	period	NOUN
admet-24	74	14	of	of	ADP
admet-24	74	15	6	6	NUM
admet-24	74	16	hours	hour	NOUN
admet-24	74	17	(	(	PUNCT
admet-24	74	18	saturation	saturation	NOUN
admet-24	74	19	time	time	NOUN
admet-24	74	20	)	)	PUNCT
admet-24	74	21	at	at	ADP
admet-24	74	22	controlled	control	VERB
admet-24	74	23	temperature	temperature	NOUN
admet-24	74	24	allowing	allow	VERB
admet-24	74	25	it	it	PRON
admet-24	74	26	to	to	PART
admet-24	74	27	achieve	achieve	VERB
admet-24	74	28	thermodynamic	thermodynamic	ADJ
admet-24	74	29	equilibrium	equilibrium	NOUN
admet-24	74	30	.	.	PUNCT
admet-24	75	1	after	after	ADP
admet-24	75	2	a	a	DET
admet-24	75	3	further	further	ADJ
admet-24	75	4	18	18	NUM
admet-24	75	5	hours	hour	NOUN
admet-24	75	6	of	of	ADP
admet-24	75	7	sedimentation	sedimentation	NOUN
admet-24	75	8	,	,	PUNCT
admet-24	75	9	the	the	DET
admet-24	75	10	concentration	concentration	NOUN
admet-24	75	11	of	of	ADP
admet-24	75	12	the	the	DET
admet-24	75	13	saturated	saturate	VERB
admet-24	75	14	solution	solution	NOUN
admet-24	75	15	was	be	AUX
admet-24	75	16	measured	measure	VERB
admet-24	75	17	by	by	ADP
admet-24	75	18	uv	uv	NOUN
admet-24	75	19	spectroscopy	spectroscopy	NOUN
admet-24	75	20	.	.	PUNCT
admet-24	76	1	three	three	NUM
admet-24	76	2	aliquots	aliquot	NOUN
admet-24	76	3	were	be	AUX
admet-24	76	4	taken	take	VERB
admet-24	76	5	out	out	ADP
admet-24	76	6	with	with	ADP
admet-24	76	7	a	a	DET
admet-24	76	8	fine	fine	ADJ
admet-24	76	9	pipette	pipette	NOUN
admet-24	76	10	(	(	PUNCT
admet-24	76	11	5500	5500	NUM
admet-24	76	12	μl	μl	NOUN
admet-24	76	13	)	)	PUNCT
admet-24	76	14	from	from	ADP
admet-24	76	15	the	the	DET
admet-24	76	16	liquid	liquid	NOUN
admet-24	76	17	and	and	CCONJ
admet-24	76	18	diluted	dilute	VERB
admet-24	76	19	with	with	ADP
admet-24	76	20	the	the	DET
admet-24	76	21	solvent	solvent	NOUN
admet-24	76	22	if	if	SCONJ
admet-24	76	23	necessary	necessary	ADJ
admet-24	76	24	.	.	PUNCT
admet-24	77	1	at	at	ADV
admet-24	77	2	least	least	ADV
admet-24	77	3	three	three	NUM
admet-24	77	4	parallel	parallel	ADJ
admet-24	77	5	concentration	concentration	NOUN
admet-24	77	6	measurements	measurement	NOUN
admet-24	77	7	were	be	AUX
admet-24	77	8	carried	carry	VERB
admet-24	77	9	out	out	ADP
admet-24	77	10	and	and	CCONJ
admet-24	77	11	the	the	DET
admet-24	77	12	result	result	NOUN
admet-24	77	13	was	be	AUX
admet-24	77	14	calculated	calculate	VERB
admet-24	77	15	using	use	VERB
admet-24	77	16	9	9	NUM
admet-24	77	17	-	-	SYM
admet-24	77	18	12	12	NUM
admet-24	77	19	data	datum	NOUN
admet-24	77	20	points	point	NOUN
admet-24	77	21	.	.	PUNCT
admet-24	78	1	the	the	DET
admet-24	78	2	standard	standard	ADJ
admet-24	78	3	deviation	deviation	NOUN
admet-24	78	4	varied	varied	ADJ
admet-24	78	5	from	from	ADP
admet-24	78	6	1	1	NUM
admet-24	78	7	-	-	SYM
admet-24	78	8	13	13	NUM
admet-24	78	9	%	%	NOUN
admet-24	78	10	.	.	PUNCT
admet-24	79	1	refinement	refinement	NOUN
admet-24	79	2	of	of	ADP
admet-24	79	3	intrinsic	intrinsic	ADJ
admet-24	79	4	and	and	CCONJ
admet-24	79	5	salt	salt	NOUN
admet-24	79	6	solubility	solubility	NOUN
admet-24	79	7	and	and	CCONJ
admet-24	79	8	aggregation	aggregation	NOUN
admet-24	79	9	constants	constant	NOUN
admet-24	79	10	the	the	DET
admet-24	79	11	new	new	ADJ
admet-24	79	12	data	datum	NOUN
admet-24	79	13	analysis	analysis	NOUN
admet-24	79	14	method	method	NOUN
admet-24	79	15	uses	use	VERB
admet-24	79	16	logs	log	NOUN
admet-24	79	17	ph	ph	NOUN
admet-24	79	18	as	as	ADP
admet-24	79	19	measured	measure	VERB
admet-24	79	20	input	input	NOUN
admet-24	79	21	data	datum	NOUN
admet-24	79	22	(	(	PUNCT
admet-24	79	23	along	along	ADP
admet-24	79	24	with	with	ADP
admet-24	79	25	the	the	DET
admet-24	79	26	standard	standard	ADJ
admet-24	79	27	deviations	deviation	NOUN
admet-24	79	28	in	in	ADP
admet-24	79	29	logs	log	NOUN
admet-24	79	30	)	)	PUNCT
admet-24	79	31	into	into	ADP
admet-24	79	32	the	the	DET
admet-24	79	33	computer	computer	NOUN
admet-24	79	34	program	program	NOUN
admet-24	79	35	.	.	PUNCT
admet-24	80	1	the	the	DET
admet-24	80	2	data	datum	NOUN
admet-24	80	3	can	can	AUX
admet-24	80	4	be	be	AUX
admet-24	80	5	uv	uv	NOUN
admet-24	80	6	-	-	PUNCT
admet-24	80	7	derived	derive	VERB
admet-24	80	8	,	,	PUNCT
admet-24	80	9	potentiometric	potentiometric	NOUN
admet-24	80	10	-	-	PUNCT
admet-24	80	11	derived	derive	VERB
admet-24	80	12	,	,	PUNCT
admet-24	80	13	etc	etc	X
admet-24	80	14	.	.	X
admet-24	81	1	an	an	DET
admet-24	81	2	algorithm	algorithm	NOUN
admet-24	81	3	was	be	AUX
admet-24	81	4	developed	develop	VERB
admet-24	81	5	which	which	PRON
admet-24	81	6	considers	consider	VERB
admet-24	81	7	the	the	DET
admet-24	81	8	contributions	contribution	NOUN
admet-24	81	9	of	of	ADP
admet-24	81	10	all	all	DET
admet-24	81	11	species	specie	NOUN
admet-24	81	12	present	present	ADJ
admet-24	81	13	in	in	ADP
admet-24	81	14	solution	solution	NOUN
admet-24	81	15	,	,	PUNCT
admet-24	81	16	including	include	VERB
admet-24	81	17	universal	universal	ADJ
admet-24	81	18	buffer	buffer	NOUN
admet-24	81	19	components	component	NOUN
admet-24	81	20	(	(	PUNCT
admet-24	81	21	e.g.	e.g.	ADV
admet-24	81	22	,	,	PUNCT
admet-24	81	23	britton	britton	PROPN
admet-24	81	24	-	-	PUNCT
admet-24	81	25	robinson	robinson	PROPN
admet-24	81	26	,	,	PUNCT
admet-24	81	27	sörensen	sörensen	NOUN
admet-24	81	28	,	,	PUNCT
admet-24	81	29	prideaux	prideaux	NOUN
admet-24	81	30	-	-	PUNCT
admet-24	81	31	ward	ward	NOUN
admet-24	81	32	,	,	PUNCT
admet-24	81	33	etc	etc	X
admet-24	81	34	.	.	X
admet-24	81	35	)	)	PUNCT
admet-24	81	36	.	.	PUNCT
admet-24	82	1	the	the	DET
admet-24	82	2	approach	approach	NOUN
admet-24	82	3	does	do	AUX
admet-24	82	4	not	not	PART
admet-24	82	5	depend	depend	VERB
admet-24	82	6	on	on	ADP
admet-24	82	7	any	any	DET
admet-24	82	8	explicitly	explicitly	ADV
admet-24	82	9	derived	derive	VERB
admet-24	82	10	extensions	extension	NOUN
admet-24	82	11	of	of	ADP
admet-24	82	12	the	the	DET
admet-24	82	13	henderson	henderson	PROPN
admet-24	82	14	-	-	PUNCT
admet-24	82	15	hasselbalch	hasselbalch	PROPN
admet-24	82	16	equations	equation	NOUN
admet-24	82	17	.	.	PUNCT
admet-24	83	1	the	the	DET
admet-24	83	2	computational	computational	ADJ
admet-24	83	3	algorithm	algorithm	NOUN
admet-24	83	4	derives	derive	VERB
admet-24	83	5	its	its	PRON
admet-24	83	6	own	own	ADJ
admet-24	83	7	implicit	implicit	ADJ
admet-24	83	8	equations	equation	NOUN
admet-24	83	9	internally	internally	ADV
admet-24	83	10	,	,	PUNCT
admet-24	83	11	given	give	VERB
admet-24	83	12	any	any	DET
admet-24	83	13	practical	practical	ADJ
admet-24	83	14	number	number	NOUN
admet-24	83	15	of	of	ADP
admet-24	83	16	equilibria	equilibrium	NOUN
admet-24	83	17	and	and	CCONJ
admet-24	83	18	estimated	estimated	ADJ
admet-24	83	19	constants	constant	NOUN
admet-24	83	20	,	,	PUNCT
admet-24	83	21	which	which	PRON
admet-24	83	22	are	be	AUX
admet-24	83	23	subsequently	subsequently	ADV
admet-24	83	24	refined	refine	VERB
admet-24	83	25	by	by	ADP
admet-24	83	26	weighted	weight	VERB
admet-24	83	27	nonlinear	nonlinear	PROPN
admet-24	83	28	leastsquares	leastsquare	NOUN
admet-24	83	29	regression	regression	PROPN
admet-24	83	30	.	.	PUNCT
admet-24	84	1	so	so	ADV
admet-24	84	2	,	,	PUNCT
admet-24	84	3	in	in	ADP
admet-24	84	4	principal	principal	NOUN
admet-24	84	5	,	,	PUNCT
admet-24	84	6	drug	drug	NOUN
admet-24	84	7	-	-	PUNCT
admet-24	84	8	salt	salt	NOUN
admet-24	84	9	precipitates	precipitate	NOUN
admet-24	84	10	,	,	PUNCT
admet-24	84	11	-aggregates	-aggregate	NOUN
admet-24	84	12	,	,	PUNCT
admet-24	84	13	-complexes	-complexe	NOUN
admet-24	84	14	,	,	PUNCT
admet-24	84	15	bile	bile	NOUN
admet-24	84	16	salts	salt	NOUN
admet-24	84	17	,	,	PUNCT
admet-24	84	18	-surfactant	-surfactant	PROPN
admet-24	84	19	can	can	AUX
admet-24	84	20	be	be	AUX
admet-24	84	21	accommodated	accommodate	VERB
admet-24	84	22	[	[	X
admet-24	84	23	19	19	NUM
admet-24	84	24	]	]	PUNCT
admet-24	84	25	.	.	PUNCT
admet-24	85	1	specific	specific	ADJ
admet-24	85	2	buffer	buffer	NOUN
admet-24	85	3	-	-	PUNCT
admet-24	85	4	drug	drug	NOUN
admet-24	85	5	formed	form	VERB
admet-24	85	6	species	specie	NOUN
admet-24	85	7	can	can	AUX
admet-24	85	8	be	be	AUX
admet-24	85	9	tested	test	VERB
admet-24	85	10	,	,	PUNCT
admet-24	85	11	as	as	SCONJ
admet-24	85	12	is	be	AUX
admet-24	85	13	often	often	ADV
admet-24	85	14	necessary	necessary	ADJ
admet-24	85	15	with	with	ADP
admet-24	85	16	phosphate-	phosphate-	X
admet-24	85	17	,	,	PUNCT
admet-24	85	18	and	and	CCONJ
admet-24	85	19	sometimes	sometimes	ADV
admet-24	85	20	,	,	PUNCT
admet-24	85	21	citrate	citrate	NOUN
admet-24	85	22	-	-	PUNCT
admet-24	85	23	containing	contain	VERB
admet-24	85	24	buffers	buffer	NOUN
admet-24	85	25	.	.	PUNCT
admet-24	86	1	the	the	DET
admet-24	86	2	program	program	NOUN
admet-24	86	3	assumes	assume	VERB
admet-24	86	4	an	an	DET
admet-24	86	5	initial	initial	ADJ
admet-24	86	6	condition	condition	NOUN
admet-24	86	7	of	of	ADP
admet-24	86	8	a	a	DET
admet-24	86	9	suspension	suspension	NOUN
admet-24	86	10	of	of	ADP
admet-24	86	11	the	the	DET
admet-24	86	12	solid	solid	ADJ
admet-24	86	13	drug	drug	NOUN
admet-24	86	14	in	in	ADP
admet-24	86	15	a	a	DET
admet-24	86	16	solution	solution	NOUN
admet-24	86	17	often	often	ADV
admet-24	86	18	containing	contain	VERB
admet-24	86	19	a	a	DET
admet-24	86	20	background	background	NOUN
admet-24	86	21	electrolyte	electrolyte	NOUN
admet-24	86	22	,	,	PUNCT
admet-24	86	23	e.g.	e.g.	ADV
admet-24	86	24	,	,	PUNCT
admet-24	86	25	0.15	0.15	NUM
admet-24	86	26	m	m	NOUN
admet-24	86	27	nacl	nacl	ADJ
admet-24	86	28	,	,	PUNCT
admet-24	86	29	ideally	ideally	ADV
admet-24	86	30	with	with	ADP
admet-24	86	31	the	the	DET
admet-24	86	32	suspension	suspension	NOUN
admet-24	86	33	saturated	saturate	VERB
admet-24	86	34	over	over	ADP
admet-24	86	35	a	a	DET
admet-24	86	36	wide	wide	ADJ
admet-24	86	37	range	range	NOUN
admet-24	86	38	of	of	ADP
admet-24	86	39	ph	ph	PROPN
admet-24	86	40	.	.	PUNCT
admet-24	87	1	the	the	DET
admet-24	87	2	computer	computer	NOUN
admet-24	87	3	program	program	NOUN
admet-24	87	4	calculates	calculate	VERB
admet-24	87	5	the	the	DET
admet-24	87	6	distribution	distribution	NOUN
admet-24	87	7	of	of	ADP
admet-24	87	8	species	specie	NOUN
admet-24	87	9	corresponding	correspond	VERB
admet-24	87	10	to	to	ADP
admet-24	87	11	a	a	DET
admet-24	87	12	sequence	sequence	NOUN
admet-24	87	13	of	of	ADP
admet-24	87	14	additions	addition	NOUN
admet-24	87	15	of	of	ADP
admet-24	87	16	standardized	standardized	ADJ
admet-24	87	17	strong	strong	ADJ
admet-24	87	18	-	-	PUNCT
admet-24	87	19	acid	acid	NOUN
admet-24	87	20	titrant	titrant	NOUN
admet-24	87	21	hcl	hcl	PROPN
admet-24	87	22	(	(	PUNCT
admet-24	87	23	or	or	CCONJ
admet-24	87	24	weak	weak	ADJ
admet-24	87	25	-	-	PUNCT
admet-24	87	26	acid	acid	ADJ
admet-24	87	27	titrants	titrant	NOUN
admet-24	87	28	h3po4	h3po4	NOUN
admet-24	87	29	,	,	PUNCT
admet-24	87	30	h2so4	h2so4	PROPN
admet-24	87	31	,	,	PUNCT
admet-24	87	32	acetic	acetic	ADJ
admet-24	87	33	acid	acid	NOUN
admet-24	87	34	,	,	PUNCT
admet-24	87	35	maleic	maleic	VERB
admet-24	87	36	acid	acid	NOUN
admet-24	87	37	,	,	PUNCT
admet-24	87	38	lactic	lactic	ADJ
admet-24	87	39	acid	acid	NOUN
admet-24	87	40	)	)	PUNCT
admet-24	87	41	to	to	PART
admet-24	87	42	simulate	simulate	VERB
admet-24	87	43	the	the	DET
admet-24	87	44	suspension	suspension	NOUN
admet-24	87	45	speciation	speciation	NOUN
admet-24	87	46	down	down	ADP
admet-24	87	47	to	to	ADP
admet-24	87	48	ph	ph	PROPN
admet-24	87	49	~	~	PUNCT
admet-24	87	50	0	0	NUM
admet-24	87	51	,	,	PUNCT
admet-24	87	52	the	the	DET
admet-24	87	53	staging	staging	NOUN
admet-24	87	54	point	point	NOUN
admet-24	87	55	for	for	ADP
admet-24	87	56	the	the	DET
admet-24	87	57	next	next	ADJ
admet-24	87	58	operation	operation	NOUN
admet-24	87	59	.	.	PUNCT
admet-24	88	1	a	a	DET
admet-24	88	2	sequence	sequence	NOUN
admet-24	88	3	of	of	ADP
admet-24	88	4	perturbations	perturbation	NOUN
admet-24	88	5	with	with	ADP
admet-24	88	6	standardized	standardized	ADJ
admet-24	88	7	naoh	naoh	NOUN
admet-24	88	8	(	(	PUNCT
admet-24	88	9	or	or	CCONJ
admet-24	88	10	koh	koh	PROPN
admet-24	88	11	)	)	PUNCT
admet-24	88	12	is	be	AUX
admet-24	88	13	simulated	simulate	VERB
admet-24	88	14	,	,	PUNCT
admet-24	88	15	and	and	CCONJ
admet-24	88	16	solubility	solubility	NOUN
admet-24	88	17	calculated	calculate	VERB
admet-24	88	18	at	at	ADP
admet-24	88	19	each	each	DET
admet-24	88	20	point	point	NOUN
admet-24	88	21	(	(	PUNCT
admet-24	88	22	in	in	ADP
admet-24	88	23	ph	ph	ADJ
admet-24	88	24	steps	step	NOUN
admet-24	88	25	of	of	ADP
admet-24	88	26	0.005	0.005	NUM
admet-24	88	27	-	-	PUNCT
admet-24	88	28	0.2	0.2	NUM
admet-24	88	29	)	)	PUNCT
admet-24	88	30	,	,	PUNCT
admet-24	88	31	until	until	SCONJ
admet-24	88	32	ph	ph	NOUN
admet-24	88	33	~	~	PUNCT
admet-24	88	34	13	13	NUM
admet-24	88	35	is	be	AUX
admet-24	88	36	reached	reach	VERB
admet-24	88	37	.	.	PUNCT
admet-24	89	1	the	the	DET
admet-24	89	2	ionic	ionic	ADJ
admet-24	89	3	strength	strength	NOUN
admet-24	89	4	is	be	AUX
admet-24	89	5	rigorously	rigorously	ADV
admet-24	89	6	calculated	calculate	VERB
admet-24	89	7	at	at	ADP
admet-24	89	8	each	each	DET
admet-24	89	9	step	step	NOUN
admet-24	89	10	(	(	PUNCT
admet-24	89	11	cf	cf	NOUN
admet-24	89	12	,	,	PUNCT
admet-24	89	13	appendix	appendix	NOUN
admet-24	89	14	b	b	NOUN
admet-24	89	15	)	)	PUNCT
admet-24	89	16	,	,	PUNCT
admet-24	89	17	and	and	CCONJ
admet-24	89	18	pka	pka	PROPN
admet-24	89	19	values	value	NOUN
admet-24	89	20	(	(	PUNCT
admet-24	89	21	as	as	ADV
admet-24	89	22	well	well	ADV
admet-24	89	23	as	as	ADP
admet-24	89	24	solubility	solubility	NOUN
admet-24	89	25	products	product	NOUN
admet-24	89	26	,	,	PUNCT
admet-24	89	27	aggregation	aggregation	NOUN
admet-24	89	28	and	and	CCONJ
admet-24	89	29	complexation	complexation	NOUN
admet-24	89	30	constants	constant	NOUN
admet-24	89	31	)	)	PUNCT
admet-24	89	32	are	be	AUX
admet-24	89	33	accordingly	accordingly	ADV
admet-24	89	34	adjusted	adjust	VERB
admet-24	89	35	(	(	PUNCT
admet-24	89	36	cf	cf	NOUN
admet-24	89	37	.	.	NOUN
admet-24	89	38	,	,	PUNCT
admet-24	89	39	appendix	appendix	VERB
admet-24	89	40	gergely	gergely	ADV
admet-24	89	41	völgyi	völgyi	PROPN
admet-24	89	42	et	et	PROPN
admet-24	89	43	al	al	PROPN
admet-24	89	44	.	.	PROPN
admet-24	89	45	admet	admet	PROPN
admet-24	89	46	&	&	CCONJ
admet-24	89	47	dmpk	dmpk	PROPN
admet-24	89	48	1(4	1(4	NUM
admet-24	89	49	)	)	PUNCT
admet-24	89	50	(	(	PUNCT
admet-24	89	51	2013	2013	NUM
admet-24	89	52	)	)	PUNCT
admet-24	89	53	48	48	NUM
admet-24	89	54	-	-	SYM
admet-24	89	55	62	62	NUM
admet-24	89	56	52	52	NUM
admet-24	89	57	b	b	NOUN
admet-24	89	58	)	)	PUNCT
admet-24	89	59	.	.	PUNCT
admet-24	90	1	nonlinear	nonlinear	ADJ
admet-24	90	2	ph	ph	ADJ
admet-24	90	3	electrode	electrode	NOUN
admet-24	90	4	standardization	standardization	NOUN
admet-24	90	5	parameters	parameter	NOUN
admet-24	90	6	(	(	PUNCT
admet-24	90	7	eq	eq	NOUN
admet-24	90	8	.	.	NOUN
admet-24	90	9	1	1	NUM
admet-24	90	10	)	)	PUNCT
admet-24	90	11	are	be	AUX
admet-24	90	12	included	include	VERB
admet-24	90	13	in	in	ADP
admet-24	90	14	the	the	DET
admet-24	90	15	calculation	calculation	NOUN
admet-24	90	16	[	[	X
admet-24	90	17	20	20	NUM
admet-24	90	18	]	]	PUNCT
admet-24	90	19	,	,	PUNCT
admet-24	90	20	a	a	DET
admet-24	90	21	feature	feature	NOUN
admet-24	90	22	that	that	PRON
admet-24	90	23	is	be	AUX
admet-24	90	24	especially	especially	ADV
admet-24	90	25	important	important	ADJ
admet-24	90	26	for	for	ADP
admet-24	90	27	measurement	measurement	NOUN
admet-24	90	28	of	of	ADP
admet-24	90	29	accurate	accurate	ADJ
admet-24	90	30	ph	ph	NOUN
admet-24	90	31	in	in	ADP
admet-24	90	32	the	the	DET
admet-24	90	33	extreme	extreme	ADJ
admet-24	90	34	ph	ph	NOUN
admet-24	90	35	(	(	PUNCT
admet-24	90	36	<	<	X
admet-24	90	37	1	1	NUM
admet-24	90	38	or	or	CCONJ
admet-24	90	39	>	>	ADP
admet-24	90	40	12	12	NUM
admet-24	90	41	)	)	PUNCT
admet-24	90	42	regions	region	NOUN
admet-24	90	43	.	.	PUNCT
admet-24	91	1	at	at	ADP
admet-24	91	2	the	the	DET
admet-24	91	3	end	end	NOUN
admet-24	91	4	of	of	ADP
admet-24	91	5	the	the	DET
admet-24	91	6	speciation	speciation	NOUN
admet-24	91	7	simulation	simulation	NOUN
admet-24	91	8	,	,	PUNCT
admet-24	91	9	the	the	DET
admet-24	91	10	calculated	calculate	VERB
admet-24	91	11	logs	log	NOUN
admet-24	91	12	vs.	vs.	ADP
admet-24	91	13	ph	ph	ADJ
admet-24	91	14	curve	curve	NOUN
admet-24	91	15	is	be	AUX
admet-24	91	16	compared	compare	VERB
admet-24	91	17	to	to	ADP
admet-24	91	18	actual	actual	ADJ
admet-24	91	19	measured	measure	VERB
admet-24	91	20	logs	log	NOUN
admet-24	91	21	vs.	vs.	ADP
admet-24	91	22	ph	ph	PROPN
admet-24	91	23	.	.	PUNCT
admet-24	92	1	a	a	DET
admet-24	92	2	logs	log	NOUN
admet-24	92	3	-	-	PUNCT
admet-24	92	4	weighted	weight	VERB
admet-24	92	5	nonlinear	nonlinear	ADJ
admet-24	92	6	least	least	ADJ
admet-24	92	7	squares	square	NOUN
admet-24	92	8	refinement	refinement	NOUN
admet-24	92	9	commences	commence	NOUN
admet-24	92	10	to	to	PART
admet-24	92	11	refine	refine	VERB
admet-24	92	12	the	the	DET
admet-24	92	13	proposed	propose	VERB
admet-24	92	14	equilibrium	equilibrium	NOUN
admet-24	92	15	model	model	NOUN
admet-24	92	16	,	,	PUNCT
admet-24	92	17	using	use	VERB
admet-24	92	18	analytical	analytical	ADJ
admet-24	92	19	expressions	expression	NOUN
admet-24	92	20	for	for	ADP
admet-24	92	21	the	the	DET
admet-24	92	22	differential	differential	ADJ
admet-24	92	23	equations	equation	NOUN
admet-24	92	24	.	.	PUNCT
admet-24	93	1	the	the	DET
admet-24	93	2	process	process	NOUN
admet-24	93	3	is	be	AUX
admet-24	93	4	repeated	repeat	VERB
admet-24	93	5	until	until	SCONJ
admet-24	93	6	the	the	DET
admet-24	93	7	differences	difference	NOUN
admet-24	93	8	between	between	ADP
admet-24	93	9	calculated	calculate	VERB
admet-24	93	10	and	and	CCONJ
admet-24	93	11	measured	measured	ADJ
admet-24	93	12	logs	log	NOUN
admet-24	93	13	values	value	NOUN
admet-24	93	14	reach	reach	VERB
admet-24	93	15	a	a	DET
admet-24	93	16	minimum	minimum	NOUN
admet-24	93	17	.	.	PUNCT
admet-24	94	1	specifically	specifically	ADV
admet-24	94	2	,	,	PUNCT
admet-24	94	3	the	the	DET
admet-24	94	4	logs	log	NOUN
admet-24	94	5	ph	ph	NOUN
admet-24	94	6	data	datum	NOUN
admet-24	94	7	are	be	AUX
admet-24	94	8	refined	refine	VERB
admet-24	94	9	to	to	PART
admet-24	94	10	minimize	minimize	VERB
admet-24	94	11	the	the	DET
admet-24	94	12	weighted	weighted	ADJ
admet-24	94	13	residual	residual	ADJ
admet-24	94	14	function	function	NOUN
admet-24	94	15	,	,	PUNCT
admet-24	94	16			X
admet-24	94	17			VERB
admet-24	94	18			PRON
admet-24	95	1	n	n	CCONJ
admet-24	95	2	i	i	PRON
admet-24	96	1	i	i	PRON
admet-24	96	2	calc	calc	VERB
admet-24	96	3	i	i	PRON
admet-24	96	4	obs	obs	VERB
admet-24	96	5	i	i	PRON
admet-24	97	1	w	w	PROPN
admet-24	97	2	s	s	PROPN
admet-24	97	3	ss	ss	NOUN
admet-24	97	4	r	r	NOUN
admet-24	97	5	)	)	PUNCT
admet-24	97	6	(	(	PUNCT
admet-24	97	7	log	log	NOUN
admet-24	97	8	)	)	PUNCT
admet-24	97	9	log(log	log(log	NOUN
admet-24	97	10	2	2	NUM
admet-24	97	11	2	2	NUM
admet-24	97	12			X
admet-24	97	13	(	(	PUNCT
admet-24	97	14	2	2	NUM
admet-24	97	15	)	)	PUNCT
admet-24	97	16	where	where	SCONJ
admet-24	97	17	n	n	PRON
admet-24	97	18	is	be	AUX
admet-24	97	19	the	the	DET
admet-24	97	20	measured	measured	ADJ
admet-24	97	21	number	number	NOUN
admet-24	97	22	of	of	ADP
admet-24	97	23	solubility	solubility	NOUN
admet-24	97	24	values	value	NOUN
admet-24	97	25	used	use	VERB
admet-24	97	26	to	to	PART
admet-24	97	27	test	test	VERB
admet-24	97	28	the	the	DET
admet-24	97	29	model	model	NOUN
admet-24	97	30	,	,	PUNCT
admet-24	97	31	and	and	CCONJ
admet-24	97	32	logsi	logsi	PROPN
admet-24	97	33	calc	calc	NOUN
admet-24	97	34	is	be	AUX
admet-24	97	35	the	the	DET
admet-24	97	36	calculated	calculate	VERB
admet-24	97	37	log	log	NOUN
admet-24	97	38	solubility	solubility	NOUN
admet-24	97	39	values	value	NOUN
admet-24	97	40	.	.	PUNCT
admet-24	98	1	the	the	DET
admet-24	98	2	estimated	estimate	VERB
admet-24	98	3	standard	standard	ADJ
admet-24	98	4	deviation	deviation	NOUN
admet-24	98	5	in	in	ADP
admet-24	98	6	the	the	DET
admet-24	98	7	observed	observe	VERB
admet-24	98	8	logs	log	NOUN
admet-24	98	9	,	,	PUNCT
admet-24	98	10	i	i	PROPN
admet-24	98	11	,	,	PUNCT
admet-24	98	12	is	be	AUX
admet-24	98	13	estimated	estimate	VERB
admet-24	98	14	as	as	ADP
admet-24	98	15	0.10	0.10	NUM
admet-24	98	16	(	(	PUNCT
admet-24	98	17	log	log	NOUN
admet-24	98	18	units	unit	NOUN
admet-24	98	19	)	)	PUNCT
admet-24	98	20	,	,	PUNCT
admet-24	98	21	or	or	CCONJ
admet-24	98	22	is	be	AUX
admet-24	98	23	set	set	VERB
admet-24	98	24	equal	equal	ADJ
admet-24	98	25	to	to	ADP
admet-24	98	26	the	the	DET
admet-24	98	27	values	value	NOUN
admet-24	98	28	reported	report	VERB
admet-24	98	29	in	in	ADP
admet-24	98	30	the	the	DET
admet-24	98	31	measurement	measurement	NOUN
admet-24	98	32	.	.	PUNCT
admet-24	99	1	the	the	DET
admet-24	99	2	overall	overall	ADJ
admet-24	99	3	quality	quality	NOUN
admet-24	99	4	of	of	ADP
admet-24	99	5	the	the	DET
admet-24	99	6	refinement	refinement	NOUN
admet-24	99	7	is	be	AUX
admet-24	99	8	assessed	assess	VERB
admet-24	99	9	by	by	ADP
admet-24	99	10	the	the	DET
admet-24	99	11	"	"	PUNCT
admet-24	99	12	goodness	goodness	NOUN
admet-24	99	13	-	-	PUNCT
admet-24	99	14	of	of	ADP
admet-24	99	15	-	-	PUNCT
admet-24	99	16	fit	fit	NOUN
admet-24	99	17	"	"	PUNCT
admet-24	99	18	(	(	PUNCT
admet-24	99	19	gof	gof	NOUN
admet-24	99	20	)	)	PUNCT
admet-24	99	21	,	,	PUNCT
admet-24	99	22	p	p	PROPN
admet-24	99	23	w	w	PROPN
admet-24	99	24	nn	nn	PROPN
admet-24	99	25	r	r	NOUN
admet-24	99	26	gof	gof	PROPN
admet-24	99	27			PROPN
admet-24	99	28			PROPN
admet-24	99	29	(	(	PUNCT
admet-24	99	30	3	3	NUM
admet-24	99	31	)	)	PUNCT
admet-24	99	32	where	where	SCONJ
admet-24	99	33	np	np	PRON
admet-24	99	34	is	be	AUX
admet-24	99	35	the	the	DET
admet-24	99	36	number	number	NOUN
admet-24	99	37	of	of	ADP
admet-24	99	38	refined	refined	ADJ
admet-24	99	39	parameters	parameter	NOUN
admet-24	99	40	.	.	PUNCT
admet-24	100	1	if	if	SCONJ
admet-24	100	2	a	a	DET
admet-24	100	3	proposed	propose	VERB
admet-24	100	4	model	model	NOUN
admet-24	100	5	fits	fit	VERB
admet-24	100	6	the	the	DET
admet-24	100	7	data	datum	NOUN
admet-24	100	8	well	well	ADV
admet-24	100	9	,	,	PUNCT
admet-24	100	10	and	and	CCONJ
admet-24	100	11	accurate	accurate	ADJ
admet-24	100	12	weighting	weighting	NOUN
admet-24	100	13	factors	factor	NOUN
admet-24	100	14	are	be	AUX
admet-24	100	15	used	use	VERB
admet-24	100	16	,	,	PUNCT
admet-24	100	17	then	then	ADV
admet-24	100	18	gof	gof	NOUN
admet-24	100	19	=	=	SYM
admet-24	100	20	1	1	NUM
admet-24	100	21	is	be	AUX
admet-24	100	22	the	the	DET
admet-24	100	23	statistically	statistically	ADV
admet-24	100	24	expected	expect	VERB
admet-24	100	25	value	value	NOUN
admet-24	100	26	.	.	PUNCT
admet-24	101	1	results	result	NOUN
admet-24	101	2	and	and	CCONJ
admet-24	101	3	discussion	discussion	NOUN
admet-24	101	4	table	table	NOUN
admet-24	101	5	1	1	NUM
admet-24	101	6	summarizes	summarize	NOUN
admet-24	101	7	some	some	PRON
admet-24	101	8	of	of	ADP
admet-24	101	9	the	the	DET
admet-24	101	10	physicochemical	physicochemical	ADJ
admet-24	101	11	properties	property	NOUN
admet-24	101	12	of	of	ADP
admet-24	101	13	the	the	DET
admet-24	101	14	three	three	NUM
admet-24	101	15	model	model	NOUN
admet-24	101	16	compounds	compound	NOUN
admet-24	101	17	,	,	PUNCT
admet-24	101	18	including	include	VERB
admet-24	101	19	the	the	DET
admet-24	101	20	pka	pka	PROPN
admet-24	101	21	constants	constant	NOUN
admet-24	101	22	of	of	ADP
admet-24	101	23	diprenorphine	diprenorphine	NOUN
admet-24	101	24	determined	determine	VERB
admet-24	101	25	in	in	ADP
admet-24	101	26	this	this	DET
admet-24	101	27	work	work	NOUN
admet-24	101	28	.	.	PUNCT
admet-24	102	1	table	table	NOUN
admet-24	102	2	2	2	NUM
admet-24	102	3	lists	list	VERB
admet-24	102	4	the	the	DET
admet-24	102	5	shake	shake	NOUN
admet-24	102	6	-	-	PUNCT
admet-24	102	7	flask	flask	NOUN
admet-24	102	8	solubility	solubility	NOUN
admet-24	102	9	measurement	measurement	NOUN
admet-24	102	10	details	detail	NOUN
admet-24	102	11	,	,	PUNCT
admet-24	102	12	including	include	VERB
admet-24	102	13	the	the	DET
admet-24	102	14	actual	actual	ADJ
admet-24	102	15	weights	weight	NOUN
admet-24	102	16	of	of	ADP
admet-24	102	17	compounds	compound	NOUN
admet-24	102	18	added	add	VERB
admet-24	102	19	to	to	PART
admet-24	102	20	form	form	VERB
admet-24	102	21	the	the	DET
admet-24	102	22	saturated	saturate	VERB
admet-24	102	23	solutions	solution	NOUN
admet-24	102	24	.	.	PUNCT
admet-24	103	1	in	in	ADP
admet-24	103	2	critical	critical	ADJ
admet-24	103	3	salt	salt	NOUN
admet-24	103	4	solubility	solubility	NOUN
admet-24	103	5	studies	study	NOUN
admet-24	103	6	,	,	PUNCT
admet-24	103	7	it	it	PRON
admet-24	103	8	is	be	AUX
admet-24	103	9	often	often	ADV
admet-24	103	10	necessary	necessary	ADJ
admet-24	103	11	to	to	PART
admet-24	103	12	state	state	VERB
admet-24	103	13	the	the	DET
admet-24	103	14	actual	actual	ADJ
admet-24	103	15	weight	weight	NOUN
admet-24	103	16	of	of	ADP
admet-24	103	17	compound	compound	NOUN
admet-24	103	18	added	add	VERB
admet-24	103	19	,	,	PUNCT
admet-24	103	20	and	and	CCONJ
admet-24	103	21	not	not	PART
admet-24	103	22	just	just	ADV
admet-24	103	23	state	state	NOUN
admet-24	103	24	that	that	SCONJ
admet-24	103	25	“	"	PUNCT
admet-24	103	26	excess	excess	ADJ
admet-24	103	27	solid	solid	NOUN
admet-24	103	28	was	be	AUX
admet-24	103	29	added	add	VERB
admet-24	103	30	.	.	PUNCT
admet-24	103	31	”	"	PUNCT
admet-24	104	1	this	this	PRON
admet-24	104	2	is	be	AUX
admet-24	104	3	because	because	SCONJ
admet-24	104	4	salt	salt	NOUN
admet-24	104	5	solubility	solubility	NOUN
admet-24	104	6	constants	constant	NOUN
admet-24	104	7	are	be	AUX
admet-24	104	8	conditional	conditional	ADJ
admet-24	104	9	,	,	PUNCT
admet-24	104	10	and	and	CCONJ
admet-24	104	11	in	in	ADP
admet-24	104	12	some	some	DET
admet-24	104	13	cases	case	NOUN
admet-24	104	14	require	require	VERB
admet-24	104	15	the	the	DET
admet-24	104	16	actual	actual	ADJ
admet-24	104	17	weights	weight	NOUN
admet-24	104	18	to	to	PART
admet-24	104	19	determine	determine	VERB
admet-24	104	20	solubility	solubility	NOUN
admet-24	104	21	products	product	NOUN
admet-24	104	22	,	,	PUNCT
admet-24	104	23	especially	especially	ADV
admet-24	104	24	when	when	SCONJ
admet-24	104	25	aggregates	aggregate	NOUN
admet-24	104	26	form	form	VERB
admet-24	104	27	in	in	ADP
admet-24	104	28	saturated	saturate	VERB
admet-24	104	29	solutions	solution	NOUN
admet-24	104	30	or	or	CCONJ
admet-24	104	31	when	when	SCONJ
admet-24	104	32	salt	salt	NOUN
admet-24	104	33	stoichiometries	stoichiometry	NOUN
admet-24	104	34	are	be	AUX
admet-24	104	35	complex	complex	ADJ
admet-24	104	36	.	.	PUNCT
admet-24	105	1	in	in	ADP
admet-24	105	2	table	table	NOUN
admet-24	105	3	2	2	NUM
admet-24	105	4	,	,	PUNCT
admet-24	105	5	the	the	DET
admet-24	105	6	calculated	calculate	VERB
admet-24	105	7	volumes	volume	NOUN
admet-24	105	8	of	of	ADP
admet-24	105	9	14.85	14.85	NUM
admet-24	105	10	m	m	NOUN
admet-24	105	11	h3po4	h3po4	NOUN
admet-24	105	12	or	or	CCONJ
admet-24	105	13	0.5	0.5	NUM
admet-24	105	14	m	m	NOUN
admet-24	105	15	koh	koh	PROPN
admet-24	105	16	titrants	titrant	NOUN
admet-24	105	17	used	use	VERB
admet-24	105	18	to	to	PART
admet-24	105	19	adjust	adjust	VERB
admet-24	105	20	the	the	DET
admet-24	105	21	ph	ph	NOUN
admet-24	105	22	are	be	AUX
admet-24	105	23	normalized	normalize	VERB
admet-24	105	24	to	to	ADP
admet-24	105	25	1	1	NUM
admet-24	105	26	ml	ml	NOUN
admet-24	105	27	total	total	ADJ
admet-24	105	28	solution	solution	NOUN
admet-24	105	29	volumes	volume	NOUN
admet-24	105	30	(	(	PUNCT
admet-24	105	31	actual	actual	ADJ
admet-24	105	32	volumes	volume	NOUN
admet-24	105	33	ranged	range	VERB
admet-24	105	34	from	from	ADP
admet-24	105	35	0.5	0.5	NUM
admet-24	105	36	to	to	PART
admet-24	105	37	15	15	NUM
admet-24	105	38	ml	ml	NOUN
admet-24	105	39	)	)	PUNCT
admet-24	105	40	.	.	PUNCT
admet-24	106	1	table	table	NOUN
admet-24	106	2	3	3	NUM
admet-24	106	3	lists	list	VERB
admet-24	106	4	the	the	DET
admet-24	106	5	equilibrium	equilibrium	NOUN
admet-24	106	6	constants	constant	NOUN
admet-24	106	7	determined	determine	VERB
admet-24	106	8	and	and	CCONJ
admet-24	106	9	critical	critical	ADJ
admet-24	106	10	concentrations	concentration	NOUN
admet-24	106	11	(	(	PUNCT
admet-24	106	12	including	include	VERB
admet-24	106	13	ionic	ionic	ADJ
admet-24	106	14	strength	strength	NOUN
admet-24	106	15	and	and	CCONJ
admet-24	106	16	buffer	buffer	NOUN
admet-24	106	17	capacity	capacity	NOUN
admet-24	106	18	)	)	PUNCT
admet-24	106	19	calculated	calculate	VERB
admet-24	106	20	in	in	ADP
admet-24	106	21	the	the	DET
admet-24	106	22	various	various	ADJ
admet-24	106	23	assays	assay	NOUN
admet-24	106	24	.	.	PUNCT
admet-24	107	1	the	the	DET
admet-24	107	2	pka	pka	PROPN
admet-24	107	3	values	value	NOUN
admet-24	107	4	of	of	ADP
admet-24	107	5	the	the	DET
admet-24	107	6	model	model	NOUN
admet-24	107	7	compounds	compound	NOUN
admet-24	107	8	are	be	AUX
admet-24	107	9	listed	list	VERB
admet-24	107	10	in	in	ADP
admet-24	107	11	table	table	NOUN
admet-24	107	12	1	1	NUM
admet-24	107	13	at	at	ADP
admet-24	107	14	standard	standard	ADJ
admet-24	107	15	state	state	NOUN
admet-24	107	16	conditions	condition	NOUN
admet-24	107	17	(	(	PUNCT
admet-24	107	18	iref	iref	NOUN
admet-24	107	19	=	=	PUNCT
admet-24	107	20	0.15	0.15	NUM
admet-24	107	21	m	m	NOUN
admet-24	107	22	,	,	PUNCT
admet-24	107	23	25	25	NUM
admet-24	107	24	oc	oc	NOUN
admet-24	107	25	)	)	PUNCT
admet-24	107	26	,	,	PUNCT
admet-24	107	27	but	but	CCONJ
admet-24	107	28	the	the	DET
admet-24	107	29	primed	prime	VERB
admet-24	107	30	constants	constant	NOUN
admet-24	107	31	in	in	ADP
admet-24	107	32	table	table	NOUN
admet-24	107	33	3	3	NUM
admet-24	107	34	are	be	AUX
admet-24	107	35	those	those	PRON
admet-24	107	36	that	that	PRON
admet-24	107	37	were	be	AUX
admet-24	107	38	actually	actually	ADV
admet-24	107	39	applied	apply	VERB
admet-24	107	40	at	at	ADP
admet-24	107	41	the	the	DET
admet-24	107	42	specific	specific	ADJ
admet-24	107	43	ionic	ionic	ADJ
admet-24	107	44	strength	strength	NOUN
admet-24	107	45	(	(	PUNCT
admet-24	107	46	0.25	0.25	NUM
admet-24	107	47	–	–	PUNCT
admet-24	107	48	4.34	4.34	NUM
admet-24	107	49	m	m	NOUN
admet-24	107	50	)	)	PUNCT
admet-24	107	51	,	,	PUNCT
admet-24	107	52	calculated	calculate	VERB
admet-24	107	53	as	as	SCONJ
admet-24	107	54	described	describe	VERB
admet-24	107	55	in	in	ADP
admet-24	107	56	appendix	appendix	PROPN
admet-24	107	57	b.	b.	PROPN
admet-24	108	1	those	those	PRON
admet-24	108	2	of	of	ADP
admet-24	108	3	diprenorphine	diprenorphine	NOUN
admet-24	108	4	changed	change	VERB
admet-24	108	5	slightly	slightly	ADV
admet-24	108	6	by	by	ADP
admet-24	108	7	0.0	0.0	NUM
admet-24	108	8	to	to	PART
admet-24	108	9	+0.05	+0.05	PROPN
admet-24	108	10	(	(	PUNCT
admet-24	108	11	pka1	pka1	PROPN
admet-24	108	12	)	)	PUNCT
admet-24	108	13	and	and	CCONJ
admet-24	108	14	0.0	0.0	NUM
admet-24	108	15	to	to	PART
admet-24	108	16	-0.04	-0.04	NUM
admet-24	108	17	(	(	PUNCT
admet-24	108	18	pka2	pka2	PROPN
admet-24	108	19	)	)	PUNCT
admet-24	108	20	;	;	PUNCT
admet-24	109	1	that	that	PRON
admet-24	109	2	of	of	ADP
admet-24	109	3	codeine	codeine	NOUN
admet-24	109	4	+0.02	+0.02	PROPN
admet-24	109	5	to	to	ADP
admet-24	109	6	+0.14	+0.14	PROPN
admet-24	109	7	;	;	PUNCT
admet-24	109	8	that	that	PRON
admet-24	109	9	of	of	ADP
admet-24	109	10	lidocaine	lidocaine	NOUN
admet-24	109	11	+0.15	+0.15	PROPN
admet-24	109	12	to	to	ADP
admet-24	109	13	+0.51	+0.51	PROPN
admet-24	109	14	.	.	PUNCT
admet-24	110	1	according	accord	VERB
admet-24	110	2	to	to	ADP
admet-24	110	3	the	the	DET
admet-24	110	4	simple	simple	ADJ
admet-24	110	5	debye	debye	ADJ
admet-24	110	6	-	-	PUNCT
admet-24	110	7	hückel	hückel	NOUN
admet-24	110	8	theory	theory	NOUN
admet-24	110	9	,	,	PUNCT
admet-24	110	10	those	those	PRON
admet-24	110	11	of	of	ADP
admet-24	110	12	monoprotic	monoprotic	ADJ
admet-24	110	13	bases	basis	NOUN
admet-24	110	14	are	be	AUX
admet-24	110	15	expected	expect	VERB
admet-24	110	16	not	not	PART
admet-24	110	17	to	to	PART
admet-24	110	18	change	change	VERB
admet-24	110	19	,	,	PUNCT
admet-24	110	20	but	but	CCONJ
admet-24	110	21	eq	eq	NOUN
admet-24	110	22	.	.	PUNCT
admet-24	111	1	b5	b5	PROPN
admet-24	111	2	predicts	predict	VERB
admet-24	111	3	otherwise	otherwise	ADV
admet-24	111	4	.	.	PUNCT
admet-24	112	1	also	also	ADV
admet-24	112	2	listed	list	VERB
admet-24	112	3	in	in	ADP
admet-24	112	4	table	table	NOUN
admet-24	112	5	3	3	NUM
admet-24	112	6	are	be	AUX
admet-24	112	7	the	the	DET
admet-24	112	8	actual	actual	ADJ
admet-24	112	9	pksp	pksp	ADJ
admet-24	112	10	values	value	NOUN
admet-24	112	11	used	use	VERB
admet-24	112	12	at	at	ADP
admet-24	112	13	the	the	DET
admet-24	112	14	particular	particular	ADJ
admet-24	112	15	ionic	ionic	ADJ
admet-24	112	16	strengths	strength	NOUN
admet-24	112	17	,	,	PUNCT
admet-24	112	18	compared	compare	VERB
admet-24	112	19	to	to	ADP
admet-24	112	20	those	those	PRON
admet-24	112	21	at	at	ADP
admet-24	112	22	iref	iref	NOUN
admet-24	112	23	.	.	PUNCT
admet-24	113	1	admet	admet	PROPN
admet-24	113	2	&	&	CCONJ
admet-24	113	3	dmpk	dmpk	PROPN
admet-24	113	4	1(4	1(4	NUM
admet-24	113	5	)	)	PUNCT
admet-24	113	6	(	(	PUNCT
admet-24	113	7	2013	2013	NUM
admet-24	113	8	)	)	PUNCT
admet-24	113	9	48	48	NUM
admet-24	113	10	-	-	SYM
admet-24	113	11	62	62	NUM
admet-24	113	12	novel	novel	NOUN
admet-24	113	13	method	method	NOUN
admet-24	113	14	of	of	ADP
admet-24	113	15	salt	salt	NOUN
admet-24	113	16	solubility	solubility	NOUN
admet-24	113	17	analysis	analysis	NOUN
admet-24	113	18	doi	doi	NOUN
admet-24	113	19	:	:	PUNCT
admet-24	113	20	10.5599	10.5599	NUM
admet-24	113	21	/	/	SYM
admet-24	113	22	admet.1.4.24	admet.1.4.24	PROPN
admet-24	113	23	53	53	NUM
admet-24	113	24	table	table	NOUN
admet-24	113	25	1	1	NUM
admet-24	113	26	.	.	PUNCT
admet-24	113	27	physicochemical	physicochemical	ADJ
admet-24	113	28	properties	property	NOUN
admet-24	113	29	,	,	PUNCT
admet-24	113	30	25	25	NUM
admet-24	113	31	°	°	NOUN
admet-24	113	32	c	c	X
admet-24	113	33	.	.	PUNCT
admet-24	114	1	compound	compound	NOUN
admet-24	114	2	mw	mw	PROPN
admet-24	114	3	log	log	PROPN
admet-24	115	1	p	p	PROPN
admet-24	115	2	pka	pka	PROPN
admet-24	115	3	literature	literature	PROPN
admet-24	115	4	-log	-log	PROPN
admet-24	115	5	s0	s0	PROPN
admet-24	115	6	=	=	PUNCT
admet-24	115	7	ps0	ps0	PROPN
admet-24	116	1	[	[	X
admet-24	116	2	m	m	X
admet-24	116	3	]	]	X
admet-24	116	4	diprenorphine	diprenorphine	NOUN
admet-24	116	5	425.56	425.56	NUM
admet-24	116	6	3.81	3.81	NUM
admet-24	116	7	a	a	DET
admet-24	116	8	9.68	9.68	NUM
admet-24	116	9	±	±	NUM
admet-24	116	10	0.01	0.01	NUM
admet-24	116	11	d	d	NOUN
admet-24	116	12	,	,	PUNCT
admet-24	116	13	8.52	8.52	NUM
admet-24	116	14	±	±	NOUN
admet-24	116	15	0.01	0.01	NUM
admet-24	116	16	d	d	NOUN
admet-24	116	17	-	-	PUNCT
admet-24	116	18	codeine	codeine	PROPN
admet-24	116	19	299.36	299.36	NUM
admet-24	116	20	1.19	1.19	NUM
admet-24	116	21	b	b	NUM
admet-24	116	22	8.24	8.24	NUM
admet-24	116	23	b	b	SYM
admet-24	116	24	1.52	1.52	NUM
admet-24	116	25	e	e	NOUN
admet-24	116	26	lidocaine	lidocaine	NOUN
admet-24	116	27	234.34	234.34	NUM
admet-24	116	28	2.44c	2.44c	NUM
admet-24	116	29	7.95c	7.95c	NUM
admet-24	116	30	2.04f	2.04f	NUM
admet-24	116	31	,	,	PUNCT
admet-24	116	32	1.88	1.88	NUM
admet-24	116	33	g	g	NOUN
admet-24	116	34	,	,	PUNCT
admet-24	116	35	1.75h	1.75h	NUM
admet-24	116	36	,	,	PUNCT
admet-24	116	37	1.71i	1.71i	NUM
admet-24	116	38	a	a	DET
admet-24	116	39	calculated	calculate	VERB
admet-24	116	40	using	use	VERB
admet-24	116	41	adme	adme	NOUN
admet-24	116	42	boxes	box	NOUN
admet-24	116	43	4.9	4.9	NUM
admet-24	116	44	(	(	PUNCT
admet-24	116	45	acd	acd	NOUN
admet-24	116	46	labs	lab	NOUN
admet-24	116	47	,	,	PUNCT
admet-24	116	48	toronto	toronto	PROPN
admet-24	116	49	)	)	PUNCT
admet-24	116	50	.	.	PUNCT
admet-24	117	1	b	b	X
admet-24	118	1	[	[	X
admet-24	118	2	22	22	NUM
admet-24	118	3	]	]	X
admet-24	118	4	c	c	NOUN
admet-24	119	1	[	[	X
admet-24	119	2	23	23	NUM
admet-24	119	3	]	]	X
admet-24	119	4	d	d	X
admet-24	119	5	this	this	DET
admet-24	119	6	work	work	NOUN
admet-24	119	7	.	.	PUNCT
admet-24	120	1	e	e	X
admet-24	121	1	[	[	X
admet-24	121	2	24	24	NUM
admet-24	121	3	]	]	X
admet-24	121	4	f	f	PROPN
admet-24	122	1	[	[	X
admet-24	122	2	16	16	NUM
admet-24	122	3	]	]	PUNCT
admet-24	122	4	.	.	PUNCT
admet-24	123	1	g	g	PROPN
admet-24	124	1	[	[	X
admet-24	124	2	25	25	NUM
admet-24	124	3	]	]	PUNCT
admet-24	124	4	h	h	NOUN
admet-24	125	1	[	[	X
admet-24	125	2	26	26	NUM
admet-24	125	3	]	]	PUNCT
admet-24	125	4	i	i	PRON
admet-24	126	1	[	[	X
admet-24	126	2	27	27	NUM
admet-24	126	3	]	]	PUNCT
admet-24	126	4	the	the	DET
admet-24	126	5	solubility	solubility	NOUN
admet-24	126	6	products	product	NOUN
admet-24	126	7	are	be	AUX
admet-24	126	8	also	also	ADV
admet-24	126	9	affected	affect	VERB
admet-24	126	10	significantly	significantly	ADV
admet-24	126	11	when	when	SCONJ
admet-24	126	12	i	i	PRON
admet-24	126	13	>	>	X
admet-24	126	14	>	>	X
admet-24	126	15	iref	iref	NOUN
admet-24	126	16	.	.	PUNCT
admet-24	127	1	for	for	ADP
admet-24	127	2	example	example	NOUN
admet-24	127	3	,	,	PUNCT
admet-24	127	4	the	the	DET
admet-24	127	5	phosphate	phosphate	ADJ
admet-24	127	6	pksp	pksp	NOUN
admet-24	127	7	of	of	ADP
admet-24	127	8	codeine	codeine	PROPN
admet-24	127	9	phosphate	phosphate	NOUN
admet-24	127	10	decreased	decrease	VERB
admet-24	127	11	from	from	ADP
admet-24	127	12	1.00	1.00	NUM
admet-24	127	13	{	{	PUNCT
admet-24	127	14	1.11	1.11	NUM
admet-24	127	15	}	}	PUNCT
admet-24	127	16	at	at	ADP
admet-24	127	17	iref	iref	NOUN
admet-24	127	18	to	to	ADP
admet-24	127	19	-0.07	-0.07	NUM
admet-24	127	20	{	{	PUNCT
admet-24	127	21	0.02	0.02	NUM
admet-24	127	22	}	}	PUNCT
admet-24	127	23	at	at	ADP
admet-24	127	24	i	i	PROPN
admet-24	127	25	=	=	PROPN
admet-24	127	26	1.21	1.21	NUM
admet-24	127	27	{	{	PUNCT
admet-24	127	28	1.07	1.07	NUM
admet-24	127	29	}	}	PUNCT
admet-24	127	30	m	m	PROPN
admet-24	127	31	,	,	PUNCT
admet-24	127	32	where	where	SCONJ
admet-24	127	33	the	the	DET
admet-24	127	34	braced	braced	ADJ
admet-24	127	35	value	value	NOUN
admet-24	127	36	refers	refer	VERB
admet-24	127	37	to	to	ADP
admet-24	127	38	britton	britton	PROPN
admet-24	127	39	-	-	PUNCT
admet-24	127	40	robinson	robinson	PROPN
admet-24	127	41	universal	universal	NOUN
admet-24	127	42	and	and	CCONJ
admet-24	127	43	the	the	DET
admet-24	127	44	unbraced	unbraced	ADJ
admet-24	127	45	value	value	NOUN
admet-24	127	46	refers	refer	VERB
admet-24	127	47	to	to	PART
admet-24	127	48	sörensen	sörensen	VERB
admet-24	127	49	buffer	buffer	NOUN
admet-24	127	50	measurements	measurement	NOUN
admet-24	127	51	(	(	PUNCT
admet-24	127	52	table	table	NOUN
admet-24	127	53	3	3	NUM
admet-24	127	54	)	)	PUNCT
admet-24	127	55	.	.	PUNCT
admet-24	128	1	lidocaine	lidocaine	PROPN
admet-24	128	2	showed	show	VERB
admet-24	128	3	similar	similar	ADJ
admet-24	128	4	large	large	ADJ
admet-24	128	5	shifts	shift	NOUN
admet-24	128	6	due	due	ADP
admet-24	128	7	to	to	ADP
admet-24	128	8	the	the	DET
admet-24	128	9	large	large	ADJ
admet-24	128	10	i	i	NOUN
admet-24	128	11	=	=	SYM
admet-24	128	12	4.34	4.34	NUM
admet-24	128	13	{	{	PUNCT
admet-24	128	14	3.81	3.81	NUM
admet-24	128	15	}	}	PUNCT
admet-24	128	16	m.	m.	NOUN
admet-24	128	17	the	the	DET
admet-24	128	18	changes	change	NOUN
admet-24	128	19	were	be	AUX
admet-24	128	20	much	much	ADV
admet-24	128	21	smaller	small	ADJ
admet-24	128	22	for	for	ADP
admet-24	128	23	the	the	DET
admet-24	128	24	codeine	codeine	PROPN
admet-24	128	25	chloride	chloride	PROPN
admet-24	128	26	pksp	pksp	PROPN
admet-24	128	27	,	,	PUNCT
admet-24	128	28	since	since	SCONJ
admet-24	128	29	i	i	X
admet-24	128	30	=	=	NOUN
admet-24	128	31	0.33	0.33	NUM
admet-24	128	32	{	{	PUNCT
admet-24	128	33	0.24	0.24	NUM
admet-24	128	34	}	}	PUNCT
admet-24	128	35	m.	m.	NOUN
admet-24	128	36	table	table	NOUN
admet-24	128	37	2	2	NUM
admet-24	128	38	.	.	PUNCT
admet-24	128	39	shake	shake	NOUN
admet-24	128	40	-	-	PUNCT
admet-24	128	41	flask	flask	NOUN
admet-24	128	42	solubility	solubility	NOUN
admet-24	128	43	data	datum	NOUN
admet-24	128	44	,	,	PUNCT
admet-24	128	45	25	25	NUM
admet-24	128	46	°	°	ADP
admet-24	128	47	c	c	NOUN
admet-24	128	48	a	a	DET
admet-24	128	49	ph	ph	ADJ
admet-24	128	50	buffer	buffer	NOUN
admet-24	128	51	v	v	NOUN
admet-24	128	52	(	(	PUNCT
admet-24	128	53	14.85	14.85	NUM
admet-24	128	54	m	m	NOUN
admet-24	128	55	h3po4	h3po4	NOUN
admet-24	128	56	)	)	PUNCT
admet-24	128	57	/ml	/ml	PUNCT
admet-24	129	1	b	b	NUM
admet-24	129	2	v	v	X
admet-24	129	3	(	(	PUNCT
admet-24	129	4	0.5	0.5	NUM
admet-24	129	5	m	m	PROPN
admet-24	129	6	koh	koh	PROPN
admet-24	129	7	)	)	PUNCT
admet-24	129	8	/ml	/ml	PUNCT
admet-24	130	1	b	b	X
admet-24	130	2	s	s	X
admet-24	130	3	(	(	PUNCT
admet-24	130	4	mg	mg	PROPN
admet-24	130	5	ml	ml	PROPN
admet-24	130	6	-1	-1	PUNCT
admet-24	130	7	)	)	PUNCT
admet-24	130	8	sample	sample	NOUN
admet-24	130	9	wt	wt	PROPN
admet-24	130	10	.	.	PUNCT
admet-24	131	1	(	(	PUNCT
admet-24	131	2	g	g	PROPN
admet-24	131	3	ml	ml	PROPN
admet-24	131	4	-1	-1	PUNCT
admet-24	131	5	)	)	PUNCT
admet-24	131	6	expected	expect	VERB
admet-24	131	7	precipitate	precipitate	NOUN
admet-24	131	8	0.83	0.83	NUM
admet-24	131	9	sör	sör	NOUN
admet-24	131	10	0.4998	0.4998	NUM
admet-24	131	11	0.0000	0.0000	NUM
admet-24	131	12	4.98	4.98	NUM
admet-24	131	13	±	±	NUM
admet-24	131	14	0.04	0.04	NUM
admet-24	131	15	0.0307	0.0307	NUM
admet-24	131	16	xh2	xh2	NOUN
admet-24	131	17	+	+	CCONJ
admet-24	132	1	h2po4	h2po4	ADJ
admet-24	132	2	(	(	PUNCT
admet-24	132	3	s	s	NOUN
admet-24	132	4	)	)	PUNCT
admet-24	132	5	1.94	1.94	NUM
admet-24	132	6	sör	sör	NOUN
admet-24	132	7	0.0111	0.0111	NUM
admet-24	132	8	0.0000	0.0000	NUM
admet-24	132	9	54.1	54.1	NUM
admet-24	132	10	±	±	NUM
admet-24	132	11	1.1	1.1	NUM
admet-24	132	12	0.0601	0.0601	NUM
admet-24	132	13	xh2	xh2	NOUN
admet-24	132	14	+	+	CCONJ
admet-24	132	15	cl	cl	NOUN
admet-24	132	16	(	(	PUNCT
admet-24	132	17	s	s	X
admet-24	132	18	)	)	PUNCT
admet-24	132	19	3.53	3.53	NUM
admet-24	132	20	sör	sör	NOUN
admet-24	132	21	0.0003	0.0003	NUM
admet-24	132	22	0.0000	0.0000	NUM
admet-24	132	23	45.2	45.2	NUM
admet-24	132	24	±	±	NUM
admet-24	132	25	0.9	0.9	NUM
admet-24	132	26	0.0634	0.0634	NUM
admet-24	132	27	xh2	xh2	PROPN
admet-24	132	28	+	+	CCONJ
admet-24	132	29	cl	cl	NOUN
admet-24	132	30	(	(	PUNCT
admet-24	132	31	s	s	X
admet-24	132	32	)	)	PUNCT
admet-24	132	33	5.06	5.06	NUM
admet-24	132	34	sör	sör	VERB
admet-24	132	35	0.0000	0.0000	NUM
admet-24	132	36	0.0082	0.0082	NUM
admet-24	132	37	45.1	45.1	NUM
admet-24	132	38	±	±	NUM
admet-24	132	39	1.2	1.2	NUM
admet-24	132	40	0.0637	0.0637	NUM
admet-24	132	41	xh2	xh2	NOUN
admet-24	133	1	+	+	CCONJ
admet-24	133	2	cl	cl	NOUN
admet-24	133	3	(	(	PUNCT
admet-24	133	4	s	s	NOUN
admet-24	133	5	)	)	PUNCT
admet-24	133	6	+	+	NUM
admet-24	133	7	xh(s	xh(s	NUM
admet-24	133	8	)	)	PUNCT
admet-24	133	9	7.22	7.22	NUM
admet-24	133	10	sör	sör	VERB
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admet-24	133	12	0.4969	0.4969	NUM
admet-24	133	13	0.249	0.249	NUM
admet-24	133	14	±	±	NUM
admet-24	133	15	0.014	0.014	NUM
admet-24	133	16	0.0050	0.0050	NUM
admet-24	133	17	xh(s	xh(s	NUM
admet-24	133	18	)	)	PUNCT
admet-24	133	19	8.34	8.34	NUM
admet-24	133	20	sör	sör	VERB
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admet-24	133	22	0.5702	0.5702	NUM
admet-24	133	23	0.088	0.088	NUM
admet-24	133	24	±	±	NUM
admet-24	133	25	0.021	0.021	NUM
admet-24	133	26	0.0114	0.0114	NUM
admet-24	133	27	xh(s	xh(s	NUM
admet-24	133	28	)	)	PUNCT
admet-24	133	29	8.83	8.83	NUM
admet-24	133	30	sör	sör	VERB
admet-24	133	31	0.0000	0.0000	NUM
admet-24	133	32	0.5759	0.5759	NUM
admet-24	133	33	0.032	0.032	NUM
admet-24	133	34	±	±	NUM
admet-24	133	35	0.001	0.001	NUM
admet-24	133	36	0.0007	0.0007	NUM
admet-24	133	37	xh(s	xh(s	NUM
admet-24	133	38	)	)	PUNCT
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admet-24	133	40	sör	sör	NOUN
admet-24	133	41	0.0000	0.0000	NUM
admet-24	133	42	0.6251	0.6251	NUM
admet-24	133	43	0.667	0.667	NUM
admet-24	133	44	±	±	NUM
admet-24	133	45	0.008	0.008	NUM
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admet-24	133	48	)	)	PUNCT
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admet-24	133	50	sör	sör	NOUN
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admet-24	133	52	0.8274	0.8274	NUM
admet-24	133	53	4.79	4.79	NUM
admet-24	133	54	±	±	NUM
admet-24	133	55	0.11	0.11	NUM
admet-24	133	56	0.0051	0.0051	NUM
admet-24	133	57	xh(s	xh(s	NUM
admet-24	133	58	)	)	PUNCT
admet-24	133	59	5.00	5.00	NUM
admet-24	133	60	br	br	NOUN
admet-24	133	61	0.0000	0.0000	NUM
admet-24	133	62	0.1376	0.1376	NUM
admet-24	133	63	52.0	52.0	NUM
admet-24	133	64	±	±	NUM
admet-24	133	65	0.1	0.1	NUM
admet-24	133	66	0.1050	0.1050	NUM
admet-24	133	67	bh	bh	NOUN
admet-24	133	68	+	+	CCONJ
admet-24	133	69	cl	cl	NOUN
admet-24	133	70	(	(	PUNCT
admet-24	133	71	s	s	X
admet-24	133	72	)	)	PUNCT
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admet-24	133	74	sör	sör	NOUN
admet-24	133	75	0.0000	0.0000	NUM
admet-24	133	76	0.0044	0.0044	NUM
admet-24	133	77	53.0	53.0	NUM
admet-24	133	78	±	±	NUM
admet-24	133	79	0.1	0.1	NUM
admet-24	133	80	0.1535	0.1535	NUM
admet-24	133	81	bh	bh	NOUN
admet-24	133	82	+	+	CCONJ
admet-24	133	83	cl	cl	NOUN
admet-24	133	84	(	(	PUNCT
admet-24	133	85	s	s	NOUN
admet-24	133	86	)	)	PUNCT
admet-24	133	87	5.00	5.00	NUM
admet-24	133	88	br	br	NOUN
admet-24	133	89	0.0000	0.0000	NUM
admet-24	133	90	0.1716	0.1716	NUM
admet-24	133	91	290	290	NUM
admet-24	133	92	±	±	NUM
admet-24	133	93	38	38	NUM
admet-24	133	94	0.4950	0.4950	NUM
admet-24	133	95	bh	bh	NOUN
admet-24	133	96	+	+	CCONJ
admet-24	133	97	h2po4	h2po4	ADJ
admet-24	133	98	(	(	PUNCT
admet-24	133	99	s	s	NOUN
admet-24	133	100	)	)	PUNCT
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admet-24	133	102	sör	sör	VERB
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admet-24	133	109	bh	bh	NOUN
admet-24	133	110	+	+	CCONJ
admet-24	133	111	h2po4	h2po4	ADJ
admet-24	133	112	(	(	PUNCT
admet-24	133	113	s	s	NOUN
admet-24	133	114	)	)	PUNCT
admet-24	133	115	5.00	5.00	NUM
admet-24	133	116	br	br	NOUN
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admet-24	133	118	0.0000	0.0000	NUM
admet-24	133	119	310	310	NUM
admet-24	133	120	±	±	NUM
admet-24	133	121	15	15	NUM
admet-24	133	122	0.7700	0.7700	NUM
admet-24	133	123	bh	bh	NOUN
admet-24	133	124	+	+	CCONJ
admet-24	133	125	h2po4	h2po4	ADJ
admet-24	133	126	(	(	PUNCT
admet-24	133	127	s	s	NOUN
admet-24	133	128	)	)	PUNCT
admet-24	133	129	5.00	5.00	NUM
admet-24	133	130	sör	sör	NOUN
admet-24	133	131	0.2940	0.2940	NUM
admet-24	133	132	0.0000	0.0000	NUM
admet-24	133	133	294	294	NUM
admet-24	133	134	±	±	NUM
admet-24	133	135	10	10	NUM
admet-24	133	136	1.0300	1.0300	NUM
admet-24	133	137	bh	bh	NOUN
admet-24	133	138	+	+	CCONJ
admet-24	133	139	h2po4	h2po4	ADJ
admet-24	133	140	(	(	PUNCT
admet-24	133	141	s	s	NOUN
admet-24	133	142	)	)	PUNCT
admet-24	133	143	5.00	5.00	NUM
admet-24	133	144	br	br	NOUN
admet-24	133	145	0.0000	0.0000	NUM
admet-24	133	146	0.0064	0.0064	NUM
admet-24	133	147	>	>	PUNCT
admet-24	133	148	1000	1000	NUM
admet-24	133	149	1.0300	1.0300	NUM
admet-24	133	150	bh	bh	NOUN
admet-24	133	151	+	+	X
admet-24	133	152	cl	cl	NOUN
admet-24	133	153	(	(	PUNCT
admet-24	133	154	s	s	X
admet-24	133	155	)	)	PUNCT
admet-24	133	156	5.00	5.00	NUM
admet-24	133	157	sör	sör	NOUN
admet-24	133	158	0.0000	0.0000	NUM
admet-24	133	159	0.0042	0.0042	NUM
admet-24	133	160	>	>	PUNCT
admet-24	133	161	1000	1000	NUM
admet-24	133	162	1.1354	1.1354	NUM
admet-24	133	163	bh	bh	NOUN
admet-24	133	164	+	+	X
admet-24	133	165	cl	cl	NOUN
admet-24	133	166	(	(	PUNCT
admet-24	133	167	s	s	X
admet-24	133	168	)	)	PUNCT
admet-24	133	169	a	a	DET
admet-24	133	170	sör	sör	NOUN
admet-24	133	171	=	=	SYM
admet-24	133	172	sörensen	sörensen	NOUN
admet-24	133	173	buffer	buffer	NOUN
admet-24	133	174	(	(	PUNCT
admet-24	133	175	0.15	0.15	NUM
admet-24	133	176	m	m	NOUN
admet-24	133	177	phosphate	phosphate	ADJ
admet-24	133	178	,	,	PUNCT
admet-24	133	179	adjusted	adjust	VERB
admet-24	133	180	with	with	ADP
admet-24	133	181	naoh	naoh	NOUN
admet-24	133	182	)	)	PUNCT
admet-24	133	183	.	.	PUNCT
admet-24	134	1	br	br	NOUN
admet-24	135	1	=	=	PUNCT
admet-24	135	2	britton	britton	PROPN
admet-24	135	3	-	-	PUNCT
admet-24	135	4	robinson	robinson	PROPN
admet-24	135	5	universal	universal	ADJ
admet-24	135	6	buffer	buffer	NOUN
admet-24	135	7	(	(	PUNCT
admet-24	135	8	acetic	acetic	ADJ
admet-24	135	9	,	,	PUNCT
admet-24	135	10	phosphoric	phosphoric	NOUN
admet-24	135	11	,	,	PUNCT
admet-24	135	12	and	and	CCONJ
admet-24	135	13	boric	boric	ADJ
admet-24	135	14	acids	acid	NOUN
admet-24	135	15	,	,	PUNCT
admet-24	135	16	each	each	PRON
admet-24	135	17	at	at	ADP
admet-24	135	18	0.04	0.04	NUM
admet-24	135	19	m	m	NOUN
admet-24	135	20	,	,	PUNCT
admet-24	135	21	adjusted	adjust	VERB
admet-24	135	22	with	with	ADP
admet-24	135	23	naoh	naoh	NOUN
admet-24	135	24	to	to	ADP
admet-24	135	25	ph	ph	PROPN
admet-24	135	26	5	5	NUM
admet-24	135	27	)	)	PUNCT
admet-24	135	28	.	.	PUNCT
admet-24	136	1	b	b	NOUN
admet-24	136	2	calculated	calculate	VERB
admet-24	136	3	by	by	ADP
admet-24	136	4	pdisol	pdisol	NOUN
admet-24	136	5	-	-	PUNCT
admet-24	136	6	x.	x.	NOUN
admet-24	136	7	the	the	DET
admet-24	136	8	pka	pka	PROPN
admet-24	136	9	values	value	NOUN
admet-24	136	10	of	of	ADP
admet-24	136	11	the	the	DET
admet-24	136	12	acetate	acetate	NOUN
admet-24	136	13	,	,	PUNCT
admet-24	136	14	phosphate	phosphate	ADJ
admet-24	136	15	,	,	PUNCT
admet-24	136	16	and	and	CCONJ
admet-24	136	17	borate	borate	NOUN
admet-24	136	18	buffer	buffer	NOUN
admet-24	136	19	components	component	NOUN
admet-24	136	20	used	use	VERB
admet-24	136	21	were	be	AUX
admet-24	136	22	taken	take	VERB
admet-24	136	23	from	from	ADP
admet-24	136	24	wiki	wiki	PROPN
admet-24	136	25	-	-	PUNCT
admet-24	136	26	pka	pka	PROPN
admet-24	136	27	website	website	NOUN
admet-24	136	28	(	(	PUNCT
admet-24	136	29	<	<	X
admet-24	136	30	http://www.in-adme.com/wiki_pka.php/	http://www.in-adme.com/wiki_pka.php/	PROPN
admet-24	136	31	>	>	X
admet-24	136	32	)	)	PUNCT
admet-24	136	33	.	.	PUNCT
admet-24	137	1	these	these	PRON
admet-24	137	2	were	be	AUX
admet-24	137	3	automatically	automatically	ADV
admet-24	137	4	adjusted	adjust	VERB
admet-24	137	5	for	for	ADP
admet-24	137	6	changes	change	NOUN
admet-24	137	7	in	in	ADP
admet-24	137	8	the	the	DET
admet-24	137	9	ionic	ionic	ADJ
admet-24	137	10	strength	strength	NOUN
admet-24	137	11	by	by	ADP
admet-24	137	12	pdisol	pdisol	NOUN
admet-24	137	13	-	-	PUNCT
admet-24	137	14	x.	x.	NOUN
admet-24	137	15	the	the	DET
admet-24	137	16	changes	change	NOUN
admet-24	137	17	were	be	AUX
admet-24	137	18	most	most	ADV
admet-24	137	19	pronounced	pronounce	VERB
admet-24	137	20	with	with	ADP
admet-24	137	21	phosphoric	phosphoric	NOUN
admet-24	137	22	acid	acid	NOUN
admet-24	137	23	(	(	PUNCT
admet-24	137	24	0.17	0.17	NUM
admet-24	137	25	–	–	PUNCT
admet-24	137	26	0.62	0.62	NUM
admet-24	137	27	)	)	PUNCT
admet-24	137	28	,	,	PUNCT
admet-24	137	29	and	and	CCONJ
admet-24	137	30	were	be	AUX
admet-24	137	31	minimal	minimal	ADJ
admet-24	137	32	with	with	ADP
admet-24	137	33	acetic	acetic	ADJ
admet-24	137	34	and	and	CCONJ
admet-24	137	35	boric	boric	ADJ
admet-24	137	36	acids	acid	NOUN
admet-24	137	37	(	(	PUNCT
admet-24	137	38	0.01	0.01	NUM
admet-24	137	39	-	-	PUNCT
admet-24	137	40	0.06	0.06	NUM
admet-24	137	41	)	)	PUNCT
admet-24	137	42	.	.	PUNCT
admet-24	138	1	http://www.in-adme.com/	http://www.in-adme.com/	PROPN
admet-24	138	2	gergely	gergely	ADV
admet-24	138	3	völgyi	völgyi	PROPN
admet-24	138	4	et	et	PROPN
admet-24	138	5	al	al	PROPN
admet-24	138	6	.	.	PROPN
admet-24	138	7	admet	admet	PROPN
admet-24	138	8	&	&	CCONJ
admet-24	138	9	dmpk	dmpk	PROPN
admet-24	138	10	1(4	1(4	NUM
admet-24	138	11	)	)	PUNCT
admet-24	138	12	(	(	PUNCT
admet-24	138	13	2013	2013	NUM
admet-24	138	14	)	)	PUNCT
admet-24	138	15	48	48	NUM
admet-24	138	16	-	-	SYM
admet-24	138	17	62	62	NUM
admet-24	138	18	54	54	NUM
admet-24	138	19	diprenorphine	diprenorphine	NOUN
admet-24	138	20	hydrochloride	hydrochloride	NOUN
admet-24	138	21	figure	figure	NOUN
admet-24	138	22	1a	1a	PROPN
admet-24	138	23	shows	show	VERB
admet-24	138	24	the	the	DET
admet-24	138	25	logs	log	NOUN
admet-24	138	26	vs.	vs.	ADP
admet-24	138	27	ph	ph	NOUN
admet-24	138	28	profile	profile	NOUN
admet-24	138	29	of	of	ADP
admet-24	138	30	diprenorphine	diprenorphine	NOUN
admet-24	138	31	hydrochloride	hydrochloride	NOUN
admet-24	138	32	(	(	PUNCT
admet-24	138	33	xh2	xh2	PROPN
admet-24	138	34	+	+	NOUN
admet-24	138	35	cl-	cl-	NUM
admet-24	138	36	)	)	PUNCT
admet-24	138	37	.	.	PUNCT
admet-24	139	1	the	the	DET
admet-24	139	2	dashed	dash	VERB
admet-24	139	3	line	line	NOUN
admet-24	139	4	is	be	AUX
admet-24	139	5	calculated	calculate	VERB
admet-24	139	6	with	with	ADP
admet-24	139	7	the	the	DET
admet-24	139	8	henderson	henderson	PROPN
admet-24	139	9	-	-	PUNCT
admet-24	139	10	hasselbalch	hasselbalch	PROPN
admet-24	139	11	equation	equation	NOUN
admet-24	139	12	(	(	PUNCT
admet-24	139	13	eq	eq	NOUN
admet-24	139	14	.	.	PUNCT
admet-24	139	15	a5	a5	PROPN
admet-24	139	16	)	)	PUNCT
admet-24	139	17	,	,	PUNCT
admet-24	139	18	using	use	VERB
admet-24	139	19	the	the	DET
admet-24	139	20	two	two	NUM
admet-24	139	21	pka	pka	NOUN
admet-24	139	22	of	of	ADP
admet-24	139	23	diprenorphine	diprenorphine	NOUN
admet-24	139	24	.	.	PUNCT
admet-24	140	1	the	the	DET
admet-24	140	2	solid	solid	ADJ
admet-24	140	3	curve	curve	NOUN
admet-24	140	4	was	be	AUX
admet-24	140	5	calculated	calculate	VERB
admet-24	140	6	based	base	VERB
admet-24	140	7	on	on	ADP
admet-24	140	8	the	the	DET
admet-24	140	9	equilibrium	equilibrium	NOUN
admet-24	140	10	model	model	NOUN
admet-24	140	11	most	most	ADV
admet-24	140	12	consistent	consistent	ADJ
admet-24	140	13	with	with	ADP
admet-24	140	14	the	the	DET
admet-24	140	15	actual	actual	ADJ
admet-24	140	16	logs	log	NOUN
admet-24	140	17	measurements	measurement	NOUN
admet-24	140	18	at	at	ADP
admet-24	140	19	the	the	DET
admet-24	140	20	various	various	ADJ
admet-24	140	21	ph	ph	NOUN
admet-24	140	22	.	.	PROPN
admet-24	140	23	for	for	ADP
admet-24	140	24	ph	ph	PROPN
admet-24	140	25	>	>	X
admet-24	140	26	pka	pka	PROPN
admet-24	140	27	gibbs	gibbs	PROPN
admet-24	140	28	(	(	PUNCT
admet-24	140	29	5.07	5.07	NUM
admet-24	140	30	;	;	PUNCT
admet-24	140	31	cf	cf	NOUN
admet-24	140	32	.	.	PUNCT
admet-24	140	33	,	,	PUNCT
admet-24	140	34	appendix	appendix	VERB
admet-24	140	35	a	a	PRON
admet-24	140	36	)	)	PUNCT
admet-24	140	37	,	,	PUNCT
admet-24	140	38	the	the	DET
admet-24	140	39	precipitate	precipitate	NOUN
admet-24	140	40	is	be	AUX
admet-24	140	41	the	the	DET
admet-24	140	42	uncharged	uncharged	ADJ
admet-24	140	43	ordinary	ordinary	ADJ
admet-24	140	44	ampholyte	ampholyte	NOUN
admet-24	140	45	,	,	PUNCT
admet-24	140	46	showing	show	VERB
admet-24	140	47	the	the	DET
admet-24	140	48	characteristic	characteristic	ADJ
admet-24	140	49	parabolic	parabolic	NOUN
admet-24	140	50	shape	shape	NOUN
admet-24	140	51	.	.	PUNCT
admet-24	141	1	the	the	DET
admet-24	141	2	intrinsic	intrinsic	ADJ
admet-24	141	3	solubility	solubility	NOUN
admet-24	141	4	(	(	PUNCT
admet-24	141	5	molar	molar	ADJ
admet-24	141	6	units	unit	NOUN
admet-24	141	7	)	)	PUNCT
admet-24	141	8	was	be	AUX
admet-24	141	9	refined	refine	VERB
admet-24	141	10	as	as	ADP
admet-24	141	11	ps0	ps0	ADJ
admet-24	141	12	=	=	PUNCT
admet-24	141	13	4.60	4.60	NUM
admet-24	141	14	±	±	NUM
admet-24	141	15	0.08	0.08	NUM
admet-24	141	16	(	(	PUNCT
admet-24	141	17	s0	s0	NOUN
admet-24	141	18	=	=	SYM
admet-24	141	19	11.5	11.5	NUM
admet-24	141	20	±	±	NUM
admet-24	141	21	0.4	0.4	NUM
admet-24	141	22	µg	µg	ADP
admet-24	141	23	ml-1	ml-1	X
admet-24	141	24	)	)	PUNCT
admet-24	141	25	.	.	PUNCT
admet-24	142	1	at	at	ADP
admet-24	142	2	ph	ph	NOUN
admet-24	142	3	below	below	ADP
admet-24	142	4	the	the	DET
admet-24	142	5	gibbs	gibbs	PROPN
admet-24	142	6	pka	pka	PROPN
admet-24	142	7	,	,	PUNCT
admet-24	142	8	either	either	CCONJ
admet-24	142	9	the	the	DET
admet-24	142	10	chloride	chloride	NOUN
admet-24	142	11	or	or	CCONJ
admet-24	142	12	the	the	DET
admet-24	142	13	phosphate	phosphate	ADJ
admet-24	142	14	salt	salt	NOUN
admet-24	142	15	precipitates	precipitate	NOUN
admet-24	142	16	(	(	PUNCT
admet-24	142	17	or	or	CCONJ
admet-24	142	18	possibly	possibly	ADV
admet-24	142	19	both	both	PRON
admet-24	142	20	)	)	PUNCT
admet-24	142	21	.	.	PUNCT
admet-24	143	1	it	it	PRON
admet-24	143	2	is	be	AUX
admet-24	143	3	not	not	PART
admet-24	143	4	easy	easy	ADJ
admet-24	143	5	to	to	PART
admet-24	143	6	be	be	AUX
admet-24	143	7	certain	certain	ADJ
admet-24	143	8	which	which	DET
admet-24	143	9	form	form	NOUN
admet-24	143	10	precipitates	precipitate	NOUN
admet-24	143	11	unless	unless	SCONJ
admet-24	143	12	several	several	ADJ
admet-24	143	13	measurements	measurement	NOUN
admet-24	143	14	are	be	AUX
admet-24	143	15	made	make	VERB
admet-24	143	16	at	at	ADP
admet-24	143	17	ph	ph	NOUN
admet-24	143	18	<	<	X
admet-24	143	19	2	2	NUM
admet-24	143	20	,	,	PUNCT
admet-24	143	21	in	in	ADP
admet-24	143	22	order	order	NOUN
admet-24	143	23	to	to	PART
admet-24	143	24	exploit	exploit	VERB
admet-24	143	25	the	the	DET
admet-24	143	26	common	common	ADJ
admet-24	143	27	ion	ion	NOUN
admet-24	143	28	effect	effect	NOUN
admet-24	143	29	which	which	PRON
admet-24	143	30	would	would	AUX
admet-24	143	31	be	be	AUX
admet-24	143	32	evident	evident	ADJ
admet-24	143	33	for	for	ADP
admet-24	143	34	phosphate	phosphate	ADJ
admet-24	143	35	salt	salt	NOUN
admet-24	143	36	,	,	PUNCT
admet-24	143	37	since	since	SCONJ
admet-24	143	38	phosphoric	phosphoric	NOUN
admet-24	143	39	acid	acid	NOUN
admet-24	143	40	was	be	AUX
admet-24	143	41	used	use	VERB
admet-24	143	42	to	to	PART
admet-24	143	43	lower	lower	VERB
admet-24	143	44	the	the	DET
admet-24	143	45	ph	ph	NOUN
admet-24	143	46	.	.	PUNCT
admet-24	144	1	the	the	DET
admet-24	144	2	solubility	solubility	NOUN
admet-24	144	3	at	at	ADP
admet-24	144	4	ph	ph	PROPN
admet-24	144	5	0.83	0.83	NUM
admet-24	144	6	suggests	suggest	VERB
admet-24	144	7	that	that	SCONJ
admet-24	144	8	a	a	DET
admet-24	144	9	phosphate	phosphate	ADJ
admet-24	144	10	precipitate	precipitate	NOUN
admet-24	144	11	may	may	AUX
admet-24	144	12	form	form	VERB
admet-24	144	13	at	at	ADP
admet-24	144	14	the	the	DET
admet-24	144	15	very	very	ADV
admet-24	144	16	low	low	ADJ
admet-24	144	17	ph	ph	NOUN
admet-24	144	18	.	.	PUNCT
admet-24	145	1	in	in	ADP
admet-24	145	2	contrast	contrast	NOUN
admet-24	145	3	,	,	PUNCT
admet-24	145	4	the	the	DET
admet-24	145	5	chloride	chloride	NOUN
admet-24	145	6	model	model	NOUN
admet-24	145	7	predicts	predict	VERB
admet-24	145	8	that	that	SCONJ
admet-24	145	9	all	all	DET
admet-24	145	10	solid	solid	ADJ
admet-24	145	11	dissolves	dissolve	VERB
admet-24	145	12	at	at	ADP
admet-24	145	13	ph	ph	ADJ
admet-24	145	14	0.83	0.83	NUM
admet-24	145	15	(	(	PUNCT
admet-24	145	16	given	give	VERB
admet-24	145	17	the	the	DET
admet-24	145	18	amount	amount	NOUN
admet-24	145	19	of	of	ADP
admet-24	145	20	sample	sample	NOUN
admet-24	145	21	added	add	VERB
admet-24	145	22	)	)	PUNCT
admet-24	145	23	.	.	PUNCT
admet-24	146	1	the	the	DET
admet-24	146	2	flat	flat	ADJ
admet-24	146	3	shape	shape	NOUN
admet-24	146	4	of	of	ADP
admet-24	146	5	the	the	DET
admet-24	146	6	curve	curve	NOUN
admet-24	146	7	ph	ph	PROPN
admet-24	146	8	2–5	2–5	PROPN
admet-24	146	9	is	be	AUX
admet-24	146	10	most	most	ADV
admet-24	146	11	consistent	consistent	ADJ
admet-24	146	12	with	with	ADP
admet-24	146	13	chloride	chloride	NOUN
admet-24	146	14	precipitate	precipitate	NOUN
admet-24	146	15	.	.	PUNCT
admet-24	147	1	a	a	DET
admet-24	147	2	phosphate	phosphate	ADJ
admet-24	147	3	precipitate	precipitate	NOUN
admet-24	147	4	would	would	AUX
admet-24	147	5	be	be	AUX
admet-24	147	6	expected	expect	VERB
admet-24	147	7	to	to	PART
admet-24	147	8	show	show	VERB
admet-24	147	9	an	an	DET
admet-24	147	10	upward	upward	ADJ
admet-24	147	11	curvature	curvature	NOUN
admet-24	147	12	near	near	ADP
admet-24	147	13	the	the	DET
admet-24	147	14	gibbs	gibbs	PROPN
admet-24	147	15	pka	pka	PROPN
admet-24	147	16	.	.	PUNCT
admet-24	148	1	the	the	DET
admet-24	148	2	constant	constant	ADJ
admet-24	148	3	based	base	VERB
admet-24	148	4	on	on	ADP
admet-24	148	5	the	the	DET
admet-24	148	6	assumed	assume	VERB
admet-24	148	7	chloride	chloride	NOUN
admet-24	148	8	precipitate	precipitate	NOUN
admet-24	148	9	is	be	AUX
admet-24	148	10	pksp	pksp	NOUN
admet-24	148	11	=	=	PUNCT
admet-24	148	12	2.06	2.06	NUM
admet-24	148	13	±	±	NUM
admet-24	148	14	0.07	0.07	NUM
admet-24	148	15	(	(	PUNCT
admet-24	148	16	sxh	sxh	X
admet-24	148	17	=	=	PROPN
admet-24	148	18	44.6	44.6	NUM
admet-24	148	19	±	±	NUM
admet-24	148	20	1.5	1.5	NUM
admet-24	148	21	mg	mg	NOUN
admet-24	148	22	ml-1	ml-1	X
admet-24	148	23	,	,	PUNCT
admet-24	148	24	in	in	ADP
admet-24	148	25	hydrochloride	hydrochloride	NOUN
admet-24	148	26	equivalents	equivalent	NOUN
admet-24	148	27	)	)	PUNCT
admet-24	148	28	.	.	PUNCT
admet-24	149	1	at	at	ADP
admet-24	149	2	ph	ph	PROPN
admet-24	149	3	>	>	X
admet-24	149	4	9	9	NUM
admet-24	149	5	,	,	PUNCT
admet-24	149	6	the	the	DET
admet-24	149	7	logs	log	NOUN
admet-24	149	8	–	–	PUNCT
admet-24	149	9	ph	ph	ADJ
admet-24	149	10	curve	curve	NOUN
admet-24	149	11	shows	show	VERB
admet-24	149	12	a	a	DET
admet-24	149	13	shift	shift	NOUN
admet-24	149	14	to	to	ADP
admet-24	149	15	lower	low	ADJ
admet-24	149	16	ph	ph	VERB
admet-24	149	17	,	,	PUNCT
admet-24	149	18	compared	compare	VERB
admet-24	149	19	that	that	SCONJ
admet-24	149	20	what	what	PRON
admet-24	149	21	would	would	AUX
admet-24	149	22	be	be	AUX
admet-24	149	23	predicted	predict	VERB
admet-24	149	24	from	from	ADP
admet-24	149	25	the	the	DET
admet-24	149	26	henderson	henderson	PROPN
admet-24	149	27	-	-	PUNCT
admet-24	149	28	hasselbalch	hasselbalch	PROPN
admet-24	149	29	equation	equation	NOUN
admet-24	149	30	.	.	PUNCT
admet-24	150	1	the	the	DET
admet-24	150	2	consistent	consistent	ADJ
admet-24	150	3	interpretation	interpretation	NOUN
admet-24	150	4	of	of	ADP
admet-24	150	5	the	the	DET
admet-24	150	6	shift	shift	NOUN
admet-24	150	7	is	be	AUX
admet-24	150	8	that	that	SCONJ
admet-24	150	9	a	a	DET
admet-24	150	10	water	water	NOUN
admet-24	150	11	-	-	PUNCT
admet-24	150	12	soluble	soluble	ADJ
admet-24	150	13	mixed	mix	VERB
admet-24	150	14	-	-	PUNCT
admet-24	150	15	charge	charge	NOUN
admet-24	150	16	anionic	anionic	ADJ
admet-24	150	17	dimer	dimer	NOUN
admet-24	150	18	forms	form	NOUN
admet-24	150	19	,	,	PUNCT
admet-24	150	20	with	with	ADP
admet-24	150	21	the	the	DET
admet-24	150	22	stoichiometry	stoichiometry	NOUN
admet-24	150	23	xhx[19	xhx[19	ADV
admet-24	150	24	]	]	PUNCT
admet-24	150	25	.	.	PUNCT
admet-24	151	1	similar	similar	ADJ
admet-24	151	2	species	specie	NOUN
admet-24	151	3	have	have	AUX
admet-24	151	4	been	be	AUX
admet-24	151	5	observed	observe	VERB
admet-24	151	6	in	in	ADP
admet-24	151	7	numerous	numerous	ADJ
admet-24	151	8	studies	study	NOUN
admet-24	151	9	,	,	PUNCT
admet-24	151	10	and	and	CCONJ
admet-24	151	11	in	in	ADP
admet-24	151	12	some	some	DET
admet-24	151	13	cases	case	NOUN
admet-24	151	14	,	,	PUNCT
admet-24	151	15	lc	lc	PROPN
admet-24	151	16	/	/	SYM
admet-24	151	17	ms	ms	NOUN
admet-24	151	18	was	be	AUX
admet-24	151	19	able	able	ADJ
admet-24	151	20	to	to	PART
admet-24	151	21	corroborate	corroborate	VERB
admet-24	151	22	the	the	DET
admet-24	151	23	hypothesized	hypothesized	ADJ
admet-24	151	24	aggregate	aggregate	ADJ
admet-24	151	25	formations	formation	NOUN
admet-24	151	26	[	[	X
admet-24	151	27	18	18	NUM
admet-24	151	28	]	]	PUNCT
admet-24	151	29	.	.	PUNCT
admet-24	152	1	the	the	DET
admet-24	152	2	equilibrium	equilibrium	NOUN
admet-24	152	3	constant	constant	ADJ
admet-24	152	4	for	for	ADP
admet-24	152	5	the	the	DET
admet-24	152	6	reaction	reaction	NOUN
admet-24	152	7	xh	xh	PROPN
admet-24	152	8	+	+	SYM
admet-24	152	9	x=	x=	PROPN
admet-24	152	10	xhxis	xhxis	PROPN
admet-24	152	11	log	log	VERB
admet-24	152	12	kxhx	kxhx	PROPN
admet-24	152	13	=	=	PROPN
admet-24	153	1	5.21	5.21	NUM
admet-24	153	2	±	±	NUM
admet-24	153	3	0.18	0.18	NUM
admet-24	153	4	m-1	m-1	NOUN
admet-24	153	5	.	.	PUNCT
admet-24	154	1	admet	admet	PROPN
admet-24	154	2	&	&	CCONJ
admet-24	154	3	dmpk	dmpk	PROPN
admet-24	154	4	1(4	1(4	NUM
admet-24	154	5	)	)	PUNCT
admet-24	154	6	(	(	PUNCT
admet-24	154	7	2013	2013	NUM
admet-24	154	8	)	)	PUNCT
admet-24	154	9	48	48	NUM
admet-24	154	10	-	-	SYM
admet-24	154	11	62	62	NUM
admet-24	154	12	novel	novel	NOUN
admet-24	154	13	method	method	NOUN
admet-24	154	14	of	of	ADP
admet-24	154	15	salt	salt	NOUN
admet-24	154	16	solubility	solubility	NOUN
admet-24	154	17	analysis	analysis	NOUN
admet-24	154	18	doi	doi	NOUN
admet-24	154	19	:	:	PUNCT
admet-24	154	20	10.5599	10.5599	NUM
admet-24	154	21	/	/	SYM
admet-24	154	22	admet.1.4.24	admet.1.4.24	PROPN
admet-24	154	23	55	55	NUM
admet-24	154	24	figure	figure	NOUN
admet-24	154	25	1	1	NUM
admet-24	154	26	.	.	PUNCT
admet-24	155	1	solubility	solubility	NOUN
admet-24	155	2	-	-	PUNCT
admet-24	155	3	ph	ph	ADJ
admet-24	155	4	profiles	profile	NOUN
admet-24	155	5	of	of	ADP
admet-24	155	6	the	the	DET
admet-24	155	7	three	three	NUM
admet-24	155	8	model	model	NOUN
admet-24	155	9	drugs	drug	NOUN
admet-24	155	10	studied	study	VERB
admet-24	155	11	.	.	PUNCT
admet-24	156	1	(	(	PUNCT
admet-24	156	2	see	see	VERB
admet-24	156	3	text	text	NOUN
admet-24	156	4	)	)	PUNCT
admet-24	156	5	gergely	gergely	ADV
admet-24	156	6	völgyi	völgyi	VERB
admet-24	156	7	et	et	PROPN
admet-24	156	8	al	al	PROPN
admet-24	156	9	.	.	PROPN
admet-24	156	10	admet	admet	PROPN
admet-24	156	11	&	&	CCONJ
admet-24	156	12	dmpk	dmpk	PROPN
admet-24	156	13	1(4	1(4	NUM
admet-24	156	14	)	)	PUNCT
admet-24	156	15	(	(	PUNCT
admet-24	156	16	2013	2013	NUM
admet-24	156	17	)	)	PUNCT
admet-24	156	18	48	48	NUM
admet-24	156	19	-	-	SYM
admet-24	156	20	62	62	NUM
admet-24	156	21	56	56	NUM
admet-24	156	22	codeine	codeine	NOUN
admet-24	156	23	hydrochloride	hydrochloride	NOUN
admet-24	156	24	and	and	CCONJ
admet-24	156	25	dihydrogenphosphate	dihydrogenphosphate	ADJ
admet-24	156	26	figure	figure	NOUN
admet-24	156	27	1b	1b	NUM
admet-24	156	28	shows	show	VERB
admet-24	156	29	the	the	DET
admet-24	156	30	codeine	codeine	NOUN
admet-24	156	31	hydrochloride	hydrochloride	NOUN
admet-24	156	32	(	(	PUNCT
admet-24	156	33	bh	bh	NOUN
admet-24	156	34	+	+	CCONJ
admet-24	156	35	cl	cl	NOUN
admet-24	156	36	)	)	PUNCT
admet-24	156	37	and	and	CCONJ
admet-24	156	38	phosphate	phosphate	ADJ
admet-24	156	39	(	(	PUNCT
admet-24	156	40	bh	bh	NOUN
admet-24	156	41	+	+	CCONJ
admet-24	156	42	h2po4	h2po4	NOUN
admet-24	156	43	)	)	PUNCT
admet-24	156	44	logs	log	NOUN
admet-24	156	45	–	–	PUNCT
admet-24	156	46	ph	ph	ADJ
admet-24	156	47	profiles	profile	NOUN
admet-24	156	48	.	.	PUNCT
admet-24	157	1	the	the	DET
admet-24	157	2	curve	curve	NOUN
admet-24	157	3	was	be	AUX
admet-24	157	4	calculated	calculate	VERB
admet-24	157	5	assuming	assume	VERB
admet-24	157	6	the	the	DET
admet-24	157	7	intrinsic	intrinsic	ADJ
admet-24	157	8	solubility	solubility	NOUN
admet-24	157	9	,	,	PUNCT
admet-24	157	10	ps0	ps0	ADJ
admet-24	157	11	=	=	SYM
admet-24	157	12	1.52	1.52	NUM
admet-24	157	13	(	(	PUNCT
admet-24	157	14	s0	s0	PROPN
admet-24	157	15	=	=	PROPN
admet-24	157	16	12	12	NUM
admet-24	157	17	mg	mg	NOUN
admet-24	157	18	ml	ml	ADP
admet-24	157	19	-1	-1	INTJ
admet-24	157	20	,	,	PUNCT
admet-24	157	21	assuming	assume	VERB
admet-24	157	22	phosphate	phosphate	ADJ
admet-24	157	23	salt	salt	NOUN
admet-24	157	24	molecular	molecular	ADJ
admet-24	157	25	weight	weight	NOUN
admet-24	157	26	)	)	PUNCT
admet-24	157	27	,	,	PUNCT
admet-24	157	28	reported	report	VERB
admet-24	157	29	by	by	ADP
admet-24	157	30	kuhne	kuhne	PROPN
admet-24	157	31	et	et	PROPN
admet-24	157	32	al	al	PROPN
admet-24	157	33	.	.	PUNCT
admet-24	158	1	[	[	X
admet-24	158	2	24	24	NUM
admet-24	158	3	]	]	PUNCT
admet-24	158	4	.	.	PUNCT
admet-24	159	1	although	although	SCONJ
admet-24	159	2	single	single	ADJ
admet-24	159	3	ph	ph	ADJ
admet-24	159	4	measurements	measurement	NOUN
admet-24	159	5	were	be	AUX
admet-24	159	6	made	make	VERB
admet-24	159	7	,	,	PUNCT
admet-24	159	8	the	the	DET
admet-24	159	9	whole	whole	ADJ
admet-24	159	10	curve	curve	NOUN
admet-24	159	11	adds	add	VERB
admet-24	159	12	useful	useful	ADJ
admet-24	159	13	perspective	perspective	NOUN
admet-24	159	14	to	to	ADP
admet-24	159	15	the	the	DET
admet-24	159	16	expected	expect	VERB
admet-24	159	17	solubility	solubility	NOUN
admet-24	159	18	–	–	PUNCT
admet-24	159	19	ph	ph	NOUN
admet-24	159	20	relationship	relationship	NOUN
admet-24	159	21	.	.	PUNCT
admet-24	160	1	the	the	DET
admet-24	160	2	assignment	assignment	NOUN
admet-24	160	3	of	of	ADP
admet-24	160	4	the	the	DET
admet-24	160	5	types	type	NOUN
admet-24	160	6	of	of	ADP
admet-24	160	7	salts	salt	NOUN
admet-24	160	8	formed	form	VERB
admet-24	160	9	is	be	AUX
admet-24	160	10	possible	possible	ADJ
admet-24	160	11	in	in	ADP
admet-24	160	12	the	the	DET
admet-24	160	13	way	way	NOUN
admet-24	160	14	the	the	DET
admet-24	160	15	assays	assay	NOUN
admet-24	160	16	were	be	AUX
admet-24	160	17	designed	design	VERB
admet-24	160	18	.	.	PUNCT
admet-24	161	1	the	the	DET
admet-24	161	2	codeine	codeine	NOUN
admet-24	161	3	phosphate	phosphate	NOUN
admet-24	161	4	assay	assay	NOUN
admet-24	161	5	had	have	VERB
admet-24	161	6	no	no	DET
admet-24	161	7	source	source	NOUN
admet-24	161	8	of	of	ADP
admet-24	161	9	chloride	chloride	NOUN
admet-24	161	10	,	,	PUNCT
admet-24	161	11	and	and	CCONJ
admet-24	161	12	thus	thus	ADV
admet-24	161	13	revealed	reveal	VERB
admet-24	161	14	the	the	DET
admet-24	161	15	phosphate	phosphate	ADJ
admet-24	161	16	pksp	pksp	NOUN
admet-24	161	17	=	=	PUNCT
admet-24	161	18	1.00	1.00	NUM
admet-24	161	19	{	{	PUNCT
admet-24	161	20	1.11	1.11	NUM
admet-24	161	21	}	}	PUNCT
admet-24	161	22	.	.	PUNCT
admet-24	162	1	the	the	DET
admet-24	162	2	codeine	codeine	PROPN
admet-24	162	3	chloride	chloride	PROPN
admet-24	162	4	assay	assay	PROPN
admet-24	162	5	indicated	indicate	VERB
admet-24	162	6	a	a	DET
admet-24	162	7	significantly	significantly	ADV
admet-24	162	8	higher	high	ADJ
admet-24	162	9	pksp	pksp	NOUN
admet-24	162	10	=	=	PROPN
admet-24	162	11	1.59	1.59	NUM
admet-24	162	12	{	{	PUNCT
admet-24	162	13	1.57	1.57	NUM
admet-24	162	14	}	}	PUNCT
admet-24	162	15	,	,	PUNCT
admet-24	162	16	suggesting	suggest	VERB
admet-24	162	17	that	that	SCONJ
admet-24	162	18	the	the	DET
admet-24	162	19	salt	salt	NOUN
admet-24	162	20	precipitate	precipitate	NOUN
admet-24	162	21	was	be	AUX
admet-24	162	22	that	that	PRON
admet-24	162	23	of	of	ADP
admet-24	162	24	the	the	DET
admet-24	162	25	chloride	chloride	NOUN
admet-24	162	26	.	.	PUNCT
admet-24	163	1	furthermore	furthermore	ADV
admet-24	163	2	,	,	PUNCT
admet-24	163	3	the	the	DET
admet-24	163	4	solubility	solubility	NOUN
admet-24	163	5	product	product	NOUN
admet-24	163	6	for	for	ADP
admet-24	163	7	the	the	DET
admet-24	163	8	phosphate	phosphate	ADJ
admet-24	163	9	salt	salt	NOUN
admet-24	163	10	in	in	ADP
admet-24	163	11	the	the	DET
admet-24	163	12	case	case	NOUN
admet-24	163	13	of	of	ADP
admet-24	163	14	the	the	DET
admet-24	163	15	chloride	chloride	NOUN
admet-24	163	16	was	be	AUX
admet-24	163	17	not	not	PART
admet-24	163	18	exceeded	exceed	VERB
admet-24	163	19	(	(	PUNCT
admet-24	163	20	table	table	NOUN
admet-24	163	21	3	3	NUM
admet-24	163	22	)	)	PUNCT
admet-24	163	23	,	,	PUNCT
admet-24	163	24	suggesting	suggest	VERB
admet-24	163	25	the	the	DET
admet-24	163	26	absence	absence	NOUN
admet-24	163	27	of	of	ADP
admet-24	163	28	phosphate	phosphate	ADJ
admet-24	163	29	salt	salt	NOUN
admet-24	163	30	in	in	ADP
admet-24	163	31	the	the	DET
admet-24	163	32	chloride	chloride	NOUN
admet-24	163	33	assay	assay	NOUN
admet-24	163	34	.	.	PUNCT
admet-24	164	1	lidocaine	lidocaine	PROPN
admet-24	164	2	free	free	ADJ
admet-24	164	3	base	base	NOUN
admet-24	164	4	and	and	CCONJ
admet-24	164	5	hydrochloride	hydrochloride	NOUN
admet-24	164	6	figure	figure	NOUN
admet-24	164	7	1c	1c	NUM
admet-24	164	8	shows	show	VERB
admet-24	164	9	the	the	DET
admet-24	164	10	lidocaine	lidocaine	ADJ
admet-24	164	11	phosphate	phosphate	NOUN
admet-24	164	12	(	(	PUNCT
admet-24	164	13	bh	bh	NOUN
admet-24	164	14	+	+	CCONJ
admet-24	164	15	h2po4	h2po4	NOUN
admet-24	164	16	)	)	PUNCT
admet-24	164	17	logs	log	NOUN
admet-24	164	18	–	–	PUNCT
admet-24	164	19	ph	ph	NOUN
admet-24	164	20	profile	profile	NOUN
admet-24	164	21	.	.	PUNCT
admet-24	165	1	the	the	DET
admet-24	165	2	chloride	chloride	NOUN
admet-24	165	3	was	be	AUX
admet-24	165	4	very	very	ADV
admet-24	165	5	soluble	soluble	ADJ
admet-24	165	6	with	with	ADP
admet-24	165	7	sbh>1	sbh>1	PROPN
admet-24	165	8	g	g	PROPN
admet-24	165	9	ml-1	ml-1	PRON
admet-24	165	10	.	.	PUNCT
admet-24	166	1	the	the	DET
admet-24	166	2	chloride	chloride	PROPN
admet-24	166	3	pksp	pksp	NOUN
admet-24	166	4	in	in	ADP
admet-24	166	5	table	table	NOUN
admet-24	166	6	3	3	NUM
admet-24	166	7	refer	refer	NOUN
admet-24	166	8	to	to	ADP
admet-24	166	9	the	the	DET
admet-24	166	10	minimum	minimum	ADJ
admet-24	166	11	possible	possible	ADJ
admet-24	166	12	values	value	NOUN
admet-24	166	13	:	:	PUNCT
admet-24	166	14	pksp	pksp	PROPN
admet-24	166	15	bhcl	bhcl	NOUN
admet-24	167	1	=	=	X
admet-24	167	2	-0.99	-0.99	INTJ
admet-24	167	3	{	{	PUNCT
admet-24	167	4	-0.85	-0.85	NOUN
admet-24	167	5	}	}	PUNCT
admet-24	167	6	,	,	PUNCT
admet-24	167	7	suggesting	suggest	VERB
admet-24	167	8	that	that	SCONJ
admet-24	167	9	the	the	DET
admet-24	167	10	chloride	chloride	NOUN
admet-24	167	11	salt	salt	NOUN
admet-24	167	12	is	be	AUX
admet-24	167	13	at	at	ADP
admet-24	167	14	least	least	ADV
admet-24	167	15	50	50	NUM
admet-24	167	16	times	time	NOUN
admet-24	167	17	more	more	ADV
admet-24	167	18	soluble	soluble	ADJ
admet-24	167	19	than	than	ADP
admet-24	167	20	the	the	DET
admet-24	167	21	phosphate	phosphate	ADJ
admet-24	167	22	salt	salt	NOUN
admet-24	167	23	.	.	PUNCT
admet-24	168	1	the	the	DET
admet-24	168	2	solid	solid	ADJ
admet-24	168	3	curve	curve	NOUN
admet-24	168	4	was	be	AUX
admet-24	168	5	calculated	calculate	VERB
admet-24	168	6	assuming	assume	VERB
admet-24	168	7	the	the	DET
admet-24	168	8	intrinsic	intrinsic	ADJ
admet-24	168	9	solubility	solubility	NOUN
admet-24	168	10	,	,	PUNCT
admet-24	168	11	ps0	ps0	ADJ
admet-24	168	12	=	=	NOUN
admet-24	168	13	2.04	2.04	NUM
admet-24	168	14	(	(	PUNCT
admet-24	168	15	s0	s0	NOUN
admet-24	168	16	=	=	SYM
admet-24	168	17	2.5	2.5	NUM
admet-24	168	18	mg	mg	NOUN
admet-24	168	19	ml-1	ml-1	ADV
admet-24	168	20	,	,	PUNCT
admet-24	168	21	assuming	assume	VERB
admet-24	168	22	bh+clmolecular	bh+clmolecular	PROPN
admet-24	168	23	weight	weight	PROPN
admet-24	168	24	)	)	PUNCT
admet-24	168	25	,	,	PUNCT
admet-24	168	26	reported	report	VERB
admet-24	168	27	by	by	ADP
admet-24	168	28	bergström	bergström	NOUN
admet-24	168	29	et	et	PROPN
admet-24	168	30	al	al	PROPN
admet-24	168	31	.	.	PUNCT
admet-24	169	1	[	[	X
admet-24	169	2	16	16	NUM
admet-24	169	3	]	]	PUNCT
admet-24	169	4	.	.	PUNCT
admet-24	170	1	as	as	ADP
admet-24	170	2	in	in	ADP
admet-24	170	3	the	the	DET
admet-24	170	4	case	case	NOUN
admet-24	170	5	of	of	ADP
admet-24	170	6	the	the	DET
admet-24	170	7	codeine	codeine	NOUN
admet-24	170	8	assays	assay	NOUN
admet-24	170	9	,	,	PUNCT
admet-24	170	10	the	the	DET
admet-24	170	11	assignment	assignment	NOUN
admet-24	170	12	of	of	ADP
admet-24	170	13	the	the	DET
admet-24	170	14	types	type	NOUN
admet-24	170	15	of	of	ADP
admet-24	170	16	salts	salt	NOUN
admet-24	170	17	formed	form	VERB
admet-24	170	18	with	with	ADP
admet-24	170	19	lidocaine	lidocaine	NOUN
admet-24	170	20	is	be	AUX
admet-24	170	21	possible	possible	ADJ
admet-24	170	22	in	in	ADP
admet-24	170	23	the	the	DET
admet-24	170	24	way	way	NOUN
admet-24	170	25	the	the	DET
admet-24	170	26	assays	assay	NOUN
admet-24	170	27	were	be	AUX
admet-24	170	28	designed	design	VERB
admet-24	170	29	.	.	PUNCT
admet-24	171	1	the	the	DET
admet-24	171	2	lidocaine	lidocaine	NOUN
admet-24	171	3	free	free	ADJ
admet-24	171	4	base	base	NOUN
admet-24	171	5	assay	assay	NOUN
admet-24	171	6	had	have	VERB
admet-24	171	7	no	no	DET
admet-24	171	8	source	source	NOUN
admet-24	171	9	of	of	ADP
admet-24	171	10	chloride	chloride	NOUN
admet-24	171	11	,	,	PUNCT
admet-24	171	12	and	and	CCONJ
admet-24	171	13	thus	thus	ADV
admet-24	171	14	revealed	reveal	VERB
admet-24	171	15	the	the	DET
admet-24	171	16	phosphate	phosphate	ADJ
admet-24	171	17	pksp	pksp	NOUN
admet-24	171	18	=	=	PUNCT
admet-24	171	19	0.85	0.85	NUM
admet-24	171	20	{	{	PUNCT
admet-24	171	21	0.88	0.88	NUM
admet-24	171	22	}	}	PUNCT
admet-24	171	23	.	.	PUNCT
admet-24	172	1	the	the	DET
admet-24	172	2	solubility	solubility	NOUN
admet-24	172	3	product	product	NOUN
admet-24	172	4	for	for	ADP
admet-24	172	5	the	the	DET
admet-24	172	6	phosphate	phosphate	ADJ
admet-24	172	7	salt	salt	NOUN
admet-24	172	8	in	in	ADP
admet-24	172	9	the	the	DET
admet-24	172	10	case	case	NOUN
admet-24	172	11	of	of	ADP
admet-24	172	12	the	the	DET
admet-24	172	13	chloride	chloride	NOUN
admet-24	172	14	was	be	AUX
admet-24	172	15	not	not	PART
admet-24	172	16	exceeded	exceed	VERB
admet-24	172	17	(	(	PUNCT
admet-24	172	18	table	table	NOUN
admet-24	172	19	3	3	NUM
admet-24	172	20	)	)	PUNCT
admet-24	172	21	,	,	PUNCT
admet-24	172	22	suggesting	suggest	VERB
admet-24	172	23	the	the	DET
admet-24	172	24	absence	absence	NOUN
admet-24	172	25	of	of	ADP
admet-24	172	26	phosphate	phosphate	ADJ
admet-24	172	27	salt	salt	NOUN
admet-24	172	28	in	in	ADP
admet-24	172	29	the	the	DET
admet-24	172	30	chloride	chloride	NOUN
admet-24	172	31	assay	assay	NOUN
admet-24	172	32	.	.	PUNCT
admet-24	173	1	the	the	DET
admet-24	173	2	unfilled	unfilled	ADJ
admet-24	173	3	circle	circle	NOUN
admet-24	173	4	symbols	symbol	NOUN
admet-24	173	5	in	in	ADP
admet-24	173	6	figure	figure	NOUN
admet-24	173	7	1c	1c	NUM
admet-24	173	8	are	be	AUX
admet-24	173	9	the	the	DET
admet-24	173	10	solubility	solubility	NOUN
admet-24	173	11	values	value	NOUN
admet-24	173	12	reported	report	VERB
admet-24	173	13	by	by	ADP
admet-24	173	14	bergström	bergström	NOUN
admet-24	173	15	et	et	PROPN
admet-24	173	16	al	al	PROPN
admet-24	173	17	.	.	PUNCT
admet-24	174	1	[	[	X
admet-24	174	2	16	16	NUM
admet-24	174	3	]	]	PUNCT
admet-24	174	4	,	,	PUNCT
admet-24	174	5	using	use	VERB
admet-24	174	6	the	the	DET
admet-24	174	7	miniaturized	miniaturize	VERB
admet-24	174	8	shake	shake	NOUN
admet-24	174	9	-	-	PUNCT
admet-24	174	10	flask	flask	NOUN
admet-24	174	11	method	method	NOUN
admet-24	174	12	(	(	PUNCT
admet-24	174	13	25	25	NUM
admet-24	174	14	o	o	NOUN
admet-24	174	15	c	c	NOUN
admet-24	174	16	,	,	PUNCT
admet-24	174	17	0.15	0.15	NUM
admet-24	174	18	m	m	NOUN
admet-24	174	19	phosphate	phosphate	ADJ
admet-24	174	20	buffer	buffer	NOUN
admet-24	174	21	,	,	PUNCT
admet-24	174	22	24	24	NUM
admet-24	174	23	h	h	NOUN
admet-24	174	24	incubation	incubation	NOUN
admet-24	174	25	)	)	PUNCT
admet-24	174	26	.	.	PUNCT
admet-24	175	1	even	even	ADV
admet-24	175	2	though	though	SCONJ
admet-24	175	3	the	the	DET
admet-24	175	4	pksp	pksp	ADJ
admet-24	175	5	values	value	NOUN
admet-24	175	6	of	of	ADP
admet-24	175	7	phosphate	phosphate	ADJ
admet-24	175	8	precipitate	precipitate	NOUN
admet-24	175	9	in	in	ADP
admet-24	175	10	the	the	DET
admet-24	175	11	free	free	ADJ
admet-24	175	12	base	base	NOUN
admet-24	175	13	case	case	NOUN
admet-24	175	14	were	be	AUX
admet-24	175	15	nearly	nearly	ADV
admet-24	175	16	identical	identical	ADJ
admet-24	175	17	for	for	ADP
admet-24	175	18	the	the	DET
admet-24	175	19	two	two	NUM
admet-24	175	20	buffer	buffer	NOUN
admet-24	175	21	systems	system	NOUN
admet-24	175	22	used	use	VERB
admet-24	175	23	,	,	PUNCT
admet-24	175	24	the	the	DET
admet-24	175	25	morphology	morphology	NOUN
admet-24	175	26	of	of	ADP
admet-24	175	27	the	the	DET
admet-24	175	28	crystals	crystal	NOUN
admet-24	175	29	isolated	isolate	VERB
admet-24	175	30	was	be	AUX
admet-24	175	31	quite	quite	ADV
admet-24	175	32	different	different	ADJ
admet-24	175	33	,	,	PUNCT
admet-24	175	34	as	as	SCONJ
admet-24	175	35	shown	show	VERB
admet-24	175	36	in	in	ADP
admet-24	175	37	figure	figure	NOUN
admet-24	175	38	2	2	NUM
admet-24	175	39	,	,	PUNCT
admet-24	175	40	with	with	ADP
admet-24	175	41	the	the	DET
admet-24	175	42	sörensen	sörensen	NOUN
admet-24	175	43	buffer	buffer	NOUN
admet-24	175	44	producing	produce	VERB
admet-24	175	45	much	much	ADV
admet-24	175	46	larger	large	ADJ
admet-24	175	47	and	and	CCONJ
admet-24	175	48	better	well	ADV
admet-24	175	49	-	-	PUNCT
admet-24	175	50	formed	form	VERB
admet-24	175	51	crystals	crystal	NOUN
admet-24	175	52	,	,	PUNCT
admet-24	175	53	compared	compare	VERB
admet-24	175	54	to	to	ADP
admet-24	175	55	the	the	DET
admet-24	175	56	brittonrobinson	brittonrobinson	NOUN
admet-24	175	57	buffer	buffer	NOUN
admet-24	175	58	(	(	PUNCT
admet-24	175	59	approx	approx	PROPN
admet-24	175	60	.	.	PUNCT
admet-24	175	61	800	800	NUM
admet-24	175	62	vs.	vs.	ADP
admet-24	175	63	60	60	NUM
admet-24	175	64	µm	µm	NOUN
admet-24	175	65	,	,	PUNCT
admet-24	175	66	respectively	respectively	ADV
admet-24	175	67	)	)	PUNCT
admet-24	175	68	.	.	PUNCT
admet-24	176	1	the	the	DET
admet-24	176	2	x	x	NOUN
admet-24	176	3	-	-	NOUN
admet-24	176	4	ray	ray	NOUN
admet-24	176	5	powder	powder	NOUN
admet-24	176	6	diffractograms	diffractogram	NOUN
admet-24	176	7	in	in	ADP
admet-24	176	8	figure	figure	NOUN
admet-24	176	9	3	3	NUM
admet-24	176	10	confirmed	confirm	VERB
admet-24	176	11	that	that	SCONJ
admet-24	176	12	the	the	DET
admet-24	176	13	crystals	crystal	NOUN
admet-24	176	14	formed	form	VERB
admet-24	176	15	in	in	ADP
admet-24	176	16	the	the	DET
admet-24	176	17	free	free	ADJ
admet-24	176	18	base	base	NOUN
admet-24	176	19	assay	assay	NOUN
admet-24	176	20	were	be	AUX
admet-24	176	21	those	those	PRON
admet-24	176	22	of	of	ADP
admet-24	176	23	the	the	DET
admet-24	176	24	same	same	ADJ
admet-24	176	25	phosphate	phosphate	ADJ
admet-24	176	26	salt	salt	NOUN
admet-24	176	27	polymorph	polymorph	NOUN
admet-24	176	28	.	.	PUNCT
admet-24	177	1	admet	admet	PROPN
admet-24	177	2	&	&	CCONJ
admet-24	177	3	dmpk	dmpk	PROPN
admet-24	177	4	1(4	1(4	NUM
admet-24	177	5	)	)	PUNCT
admet-24	177	6	(	(	PUNCT
admet-24	177	7	2013	2013	NUM
admet-24	177	8	)	)	PUNCT
admet-24	177	9	48	48	NUM
admet-24	177	10	-	-	SYM
admet-24	177	11	62	62	NUM
admet-24	177	12	novel	novel	NOUN
admet-24	177	13	method	method	NOUN
admet-24	177	14	of	of	ADP
admet-24	177	15	salt	salt	NOUN
admet-24	177	16	solubility	solubility	NOUN
admet-24	177	17	analysis	analysis	NOUN
admet-24	177	18	doi	doi	NOUN
admet-24	177	19	:	:	PUNCT
admet-24	177	20	10.5599	10.5599	NUM
admet-24	177	21	/	/	SYM
admet-24	177	22	admet.1.4.24	admet.1.4.24	PROPN
admet-24	177	23	57	57	NUM
admet-24	177	24	figure	figure	NOUN
admet-24	177	25	2	2	NUM
admet-24	177	26	.	.	NOUN
admet-24	177	27	microphotographs	microphotograph	NOUN
admet-24	177	28	of	of	ADP
admet-24	177	29	lidocaine	lidocaine	ADJ
admet-24	177	30	phosphate	phosphate	NOUN
admet-24	177	31	solids	solid	NOUN
admet-24	177	32	obtained	obtain	VERB
admet-24	177	33	from	from	ADP
admet-24	177	34	solubility	solubility	NOUN
admet-24	177	35	experiments	experiment	NOUN
admet-24	177	36	:	:	PUNCT
admet-24	177	37	(	(	PUNCT
admet-24	177	38	a	a	X
admet-24	177	39	)	)	PUNCT
admet-24	177	40	britton	britton	PROPN
admet-24	177	41	-	-	PUNCT
admet-24	177	42	robinson	robinson	PROPN
admet-24	177	43	buffer	buffer	NOUN
admet-24	177	44	,	,	PUNCT
admet-24	177	45	(	(	PUNCT
admet-24	177	46	b	b	X
admet-24	177	47	)	)	PUNCT
admet-24	177	48	sörensen	sörensen	NOUN
admet-24	177	49	buffer	buffer	NOUN
admet-24	177	50	.	.	PUNCT
admet-24	178	1	5	5	NUM
admet-24	178	2	10	10	NUM
admet-24	178	3	15	15	NUM
admet-24	178	4	20	20	NUM
admet-24	178	5	25	25	NUM
admet-24	178	6	30	30	NUM
admet-24	178	7	35	35	NUM
admet-24	178	8	2theta	2theta	NUM
admet-24	178	9	(	(	PUNCT
admet-24	178	10	°	°	PROPN
admet-24	178	11	)	)	PUNCT
admet-24	178	12	0	0	NUM
admet-24	178	13	500	500	NUM
admet-24	178	14	1000	1000	NUM
admet-24	178	15	1500	1500	NUM
admet-24	178	16	2000	2000	NUM
admet-24	178	17	in	in	ADP
admet-24	178	18	te	te	PROPN
admet-24	178	19	n	n	PROPN
admet-24	178	20	s	s	PRON
admet-24	178	21	it	it	PRON
admet-24	178	22	y	y	PROPN
admet-24	178	23	(	(	PUNCT
admet-24	178	24	c	c	PROPN
admet-24	178	25	p	p	X
admet-24	178	26	s	s	PART
admet-24	178	27	)	)	PUNCT
admet-24	178	28	figure	figure	NOUN
admet-24	178	29	3	3	NUM
admet-24	178	30	.	.	PUNCT
admet-24	178	31	x	x	X
admet-24	178	32	-	-	NOUN
admet-24	178	33	ray	ray	NOUN
admet-24	178	34	powder	powder	NOUN
admet-24	178	35	diffractograms	diffractogram	NOUN
admet-24	178	36	of	of	ADP
admet-24	178	37	reference	reference	NOUN
admet-24	178	38	lidocaine	lidocaine	NOUN
admet-24	178	39	base	base	NOUN
admet-24	178	40	(	(	PUNCT
admet-24	178	41	blue	blue	ADJ
admet-24	178	42	)	)	PUNCT
admet-24	178	43	,	,	PUNCT
admet-24	178	44	lidocaine	lidocaine	NOUN
admet-24	178	45	phosphate	phosphate	NOUN
admet-24	178	46	from	from	ADP
admet-24	178	47	solubility	solubility	NOUN
admet-24	178	48	measurement	measurement	NOUN
admet-24	178	49	in	in	ADP
admet-24	178	50	britton	britton	PROPN
admet-24	178	51	-	-	PUNCT
admet-24	178	52	robinson	robinson	PROPN
admet-24	178	53	buffer	buffer	NOUN
admet-24	178	54	(	(	PUNCT
admet-24	178	55	brown	brown	NOUN
admet-24	178	56	)	)	PUNCT
admet-24	178	57	and	and	CCONJ
admet-24	178	58	in	in	ADP
admet-24	178	59	sörensen	sörensen	NOUN
admet-24	178	60	buffer	buffer	NOUN
admet-24	178	61	(	(	PUNCT
admet-24	178	62	orange	orange	ADJ
admet-24	178	63	)	)	PUNCT
admet-24	178	64	.	.	PUNCT
admet-24	179	1	gergely	gergely	ADV
admet-24	179	2	völgyi	völgyi	VERB
admet-24	179	3	et	et	PROPN
admet-24	179	4	al	al	PROPN
admet-24	179	5	.	.	PROPN
admet-24	179	6	admet	admet	PROPN
admet-24	179	7	&	&	CCONJ
admet-24	179	8	dmpk	dmpk	PROPN
admet-24	179	9	1(4	1(4	NUM
admet-24	179	10	)	)	PUNCT
admet-24	179	11	(	(	PUNCT
admet-24	179	12	2013	2013	NUM
admet-24	179	13	)	)	PUNCT
admet-24	179	14	48	48	NUM
admet-24	179	15	-	-	SYM
admet-24	179	16	62	62	NUM
admet-24	179	17	58	58	NUM
admet-24	179	18	conclusion	conclusion	NOUN
admet-24	179	19	the	the	DET
admet-24	179	20	design	design	NOUN
admet-24	179	21	of	of	ADP
admet-24	179	22	salt	salt	NOUN
admet-24	179	23	solubility	solubility	NOUN
admet-24	179	24	assays	assay	NOUN
admet-24	179	25	here	here	ADV
admet-24	179	26	and	and	CCONJ
admet-24	179	27	the	the	DET
admet-24	179	28	data	datum	NOUN
admet-24	179	29	analysis	analysis	NOUN
admet-24	179	30	capability	capability	NOUN
admet-24	179	31	of	of	ADP
admet-24	179	32	the	the	DET
admet-24	179	33	new	new	ADJ
admet-24	179	34	program	program	NOUN
admet-24	179	35	,	,	PUNCT
admet-24	179	36	pdisol	pdisol	NOUN
admet-24	179	37	-	-	PUNCT
admet-24	179	38	x	x	PRON
admet-24	179	39	offered	offer	VERB
admet-24	179	40	an	an	DET
admet-24	179	41	opportunity	opportunity	NOUN
admet-24	179	42	to	to	PART
admet-24	179	43	critically	critically	ADV
admet-24	179	44	investigate	investigate	VERB
admet-24	179	45	issues	issue	NOUN
admet-24	179	46	related	relate	VERB
admet-24	179	47	to	to	ADP
admet-24	179	48	the	the	DET
admet-24	179	49	challenges	challenge	NOUN
admet-24	179	50	of	of	ADP
admet-24	179	51	characterizing	characterize	VERB
admet-24	179	52	salt	salt	NOUN
admet-24	179	53	solubility	solubility	NOUN
admet-24	179	54	products	product	NOUN
admet-24	179	55	,	,	PUNCT
admet-24	179	56	such	such	ADJ
admet-24	179	57	as	as	ADP
admet-24	179	58	the	the	DET
admet-24	179	59	high	high	ADJ
admet-24	179	60	ionic	ionic	ADJ
admet-24	179	61	strengths	strength	NOUN
admet-24	179	62	,	,	PUNCT
admet-24	179	63	which	which	PRON
admet-24	179	64	can	can	AUX
admet-24	179	65	affect	affect	VERB
admet-24	179	66	values	value	NOUN
admet-24	179	67	of	of	ADP
admet-24	179	68	equilibrium	equilibrium	NOUN
admet-24	179	69	constants	constant	NOUN
admet-24	179	70	and	and	CCONJ
admet-24	179	71	the	the	DET
admet-24	179	72	calibration	calibration	NOUN
admet-24	179	73	of	of	ADP
admet-24	179	74	ph	ph	ADJ
admet-24	179	75	electrodes	electrode	NOUN
admet-24	179	76	.	.	PUNCT
admet-24	180	1	the	the	DET
admet-24	180	2	“	"	PUNCT
admet-24	180	3	anomalies	anomaly	NOUN
admet-24	180	4	”	"	PUNCT
admet-24	180	5	in	in	ADP
admet-24	180	6	the	the	DET
admet-24	180	7	shapes	shape	NOUN
admet-24	180	8	of	of	ADP
admet-24	180	9	logs	log	NOUN
admet-24	180	10	–	–	PUNCT
admet-24	180	11	ph	ph	ADJ
admet-24	180	12	profiles	profile	NOUN
admet-24	180	13	that	that	PRON
admet-24	180	14	can	can	AUX
admet-24	180	15	not	not	PART
admet-24	180	16	accurately	accurately	ADV
admet-24	180	17	be	be	AUX
admet-24	180	18	predicted	predict	VERB
admet-24	180	19	by	by	ADP
admet-24	180	20	the	the	DET
admet-24	180	21	henderson	henderson	PROPN
admet-24	180	22	-	-	PUNCT
admet-24	180	23	hasselbalch	hasselbalch	PROPN
admet-24	180	24	may	may	AUX
admet-24	180	25	be	be	AUX
admet-24	180	26	common	common	ADJ
admet-24	180	27	with	with	ADP
admet-24	180	28	sparingly	sparingly	ADV
admet-24	180	29	-	-	PUNCT
admet-24	180	30	soluble	soluble	ADJ
admet-24	180	31	or	or	CCONJ
admet-24	180	32	practically	practically	ADV
admet-24	180	33	-	-	PUNCT
admet-24	180	34	insoluble	insoluble	ADJ
admet-24	180	35	drugs	drug	NOUN
admet-24	180	36	,	,	PUNCT
admet-24	180	37	such	such	ADJ
admet-24	180	38	as	as	ADP
admet-24	180	39	diprenorphine	diprenorphine	NOUN
admet-24	180	40	,	,	PUNCT
admet-24	180	41	but	but	CCONJ
admet-24	180	42	are	be	AUX
admet-24	180	43	not	not	PART
admet-24	180	44	always	always	ADV
admet-24	180	45	easy	easy	ADJ
admet-24	180	46	to	to	PART
admet-24	180	47	recognize	recognize	VERB
admet-24	180	48	unless	unless	SCONJ
admet-24	180	49	accurately	accurately	ADV
admet-24	180	50	-	-	PUNCT
admet-24	180	51	determined	determine	VERB
admet-24	180	52	pka	pka	PROPN
admet-24	180	53	values	value	NOUN
admet-24	180	54	are	be	AUX
admet-24	180	55	available	available	ADJ
admet-24	180	56	[	[	X
admet-24	180	57	28	28	NUM
admet-24	180	58	]	]	PUNCT
admet-24	180	59	.	.	PUNCT
admet-24	181	1	phosphate	phosphate	ADJ
admet-24	181	2	buffers	buffer	NOUN
admet-24	181	3	can	can	AUX
admet-24	181	4	dramatically	dramatically	ADV
admet-24	181	5	influence	influence	VERB
admet-24	181	6	the	the	DET
admet-24	181	7	solubility	solubility	NOUN
admet-24	181	8	profiles	profile	NOUN
admet-24	181	9	of	of	ADP
admet-24	181	10	ionizable	ionizable	ADJ
admet-24	181	11	drugs	drug	NOUN
admet-24	181	12	,	,	PUNCT
admet-24	181	13	as	as	SCONJ
admet-24	181	14	shown	show	VERB
admet-24	181	15	here	here	ADV
admet-24	181	16	and	and	CCONJ
admet-24	181	17	elsewhere	elsewhere	ADV
admet-24	181	18	[	[	X
admet-24	181	19	16,29	16,29	NUM
admet-24	181	20	]	]	PUNCT
admet-24	181	21	.	.	PUNCT
admet-24	182	1	these	these	PRON
admet-24	182	2	and	and	CCONJ
admet-24	182	3	other	other	ADJ
admet-24	182	4	similar	similar	ADJ
admet-24	182	5	complications	complication	NOUN
admet-24	182	6	may	may	AUX
admet-24	182	7	be	be	AUX
admet-24	182	8	common	common	ADJ
admet-24	182	9	,	,	PUNCT
admet-24	182	10	but	but	CCONJ
admet-24	182	11	are	be	AUX
admet-24	182	12	not	not	PART
admet-24	182	13	always	always	ADV
admet-24	182	14	easy	easy	ADJ
admet-24	182	15	to	to	PART
admet-24	182	16	interpret	interpret	VERB
admet-24	182	17	quantitatively	quantitatively	ADV
admet-24	182	18	.	.	PUNCT
admet-24	183	1	in	in	ADP
admet-24	183	2	such	such	ADJ
admet-24	183	3	instances	instance	NOUN
admet-24	183	4	,	,	PUNCT
admet-24	183	5	pdisol	pdisol	NOUN
admet-24	183	6	-	-	PUNCT
admet-24	183	7	x	x	PRON
admet-24	183	8	may	may	AUX
admet-24	183	9	be	be	AUX
admet-24	183	10	a	a	DET
admet-24	183	11	helpful	helpful	ADJ
admet-24	183	12	data	data	NOUN
admet-24	183	13	analysis	analysis	NOUN
admet-24	183	14	and	and	CCONJ
admet-24	183	15	simulation	simulation	NOUN
admet-24	183	16	tool	tool	NOUN
admet-24	183	17	.	.	PUNCT
admet-24	184	1	it	it	PRON
admet-24	184	2	can	can	AUX
admet-24	184	3	further	far	ADV
admet-24	184	4	aid	aid	VERB
admet-24	184	5	in	in	ADP
admet-24	184	6	the	the	DET
admet-24	184	7	analysis	analysis	NOUN
admet-24	184	8	of	of	ADP
admet-24	184	9	dissolution	dissolution	ADJ
admet-24	184	10	mechanisms	mechanism	NOUN
admet-24	184	11	which	which	PRON
admet-24	184	12	depend	depend	VERB
admet-24	184	13	on	on	ADP
admet-24	184	14	the	the	DET
admet-24	184	15	salt	salt	NOUN
admet-24	184	16	solubility	solubility	NOUN
admet-24	184	17	of	of	ADP
admet-24	184	18	drugs	drug	NOUN
admet-24	184	19	.	.	PUNCT
admet-24	185	1	appendices	appendix	NOUN
admet-24	185	2	a	a	DET
admet-24	185	3	)	)	PUNCT
admet-24	185	4	explicit	explicit	ADJ
admet-24	185	5	solubility	solubility	NOUN
admet-24	185	6	ph	ph	NOUN
admet-24	185	7	equations	equation	NOUN
admet-24	185	8	the	the	DET
admet-24	185	9	idealized	idealized	ADJ
admet-24	185	10	relationship	relationship	NOUN
admet-24	185	11	between	between	ADP
admet-24	185	12	solubility	solubility	NOUN
admet-24	185	13	and	and	CCONJ
admet-24	185	14	ph	ph	NOUN
admet-24	185	15	can	can	AUX
admet-24	185	16	be	be	AUX
admet-24	185	17	readily	readily	ADV
admet-24	185	18	derived	derive	VERB
admet-24	185	19	for	for	ADP
admet-24	185	20	simple	simple	ADJ
admet-24	185	21	equilibrium	equilibrium	NOUN
admet-24	185	22	models	model	NOUN
admet-24	185	23	.	.	PUNCT
admet-24	186	1	the	the	DET
admet-24	186	2	"	"	PUNCT
admet-24	186	3	model	model	NOUN
admet-24	186	4	"	"	PUNCT
admet-24	186	5	refers	refer	VERB
admet-24	186	6	to	to	ADP
admet-24	186	7	a	a	DET
admet-24	186	8	set	set	NOUN
admet-24	186	9	of	of	ADP
admet-24	186	10	equilibrium	equilibrium	NOUN
admet-24	186	11	equations	equation	NOUN
admet-24	186	12	and	and	CCONJ
admet-24	186	13	the	the	DET
admet-24	186	14	associated	associated	ADJ
admet-24	186	15	equilibrium	equilibrium	NOUN
admet-24	186	16	constants	constant	NOUN
admet-24	186	17	.	.	PUNCT
admet-24	187	1	the	the	DET
admet-24	187	2	following	follow	VERB
admet-24	187	3	are	be	AUX
admet-24	187	4	examples	example	NOUN
admet-24	187	5	of	of	ADP
admet-24	187	6	such	such	ADJ
admet-24	187	7	derivations	derivation	NOUN
admet-24	187	8	correspond	correspond	VERB
admet-24	187	9	to	to	ADP
admet-24	187	10	a	a	DET
admet-24	187	11	diprotic	diprotic	ADJ
admet-24	187	12	ampholyte	ampholyte	NOUN
admet-24	187	13	.	.	PUNCT
admet-24	188	1	precipitation	precipitation	NOUN
admet-24	188	2	of	of	ADP
admet-24	188	3	diprotic	diprotic	ADJ
admet-24	188	4	amphoteric	amphoteric	ADJ
admet-24	188	5	drug	drug	NOUN
admet-24	188	6	,	,	PUNCT
admet-24	188	7	xh	xh	PROPN
admet-24	188	8	(	(	PUNCT
admet-24	188	9	henderson	henderson	PROPN
admet-24	188	10	-	-	PUNCT
admet-24	188	11	hasselbalch	hasselbalch	PROPN
admet-24	188	12	equation	equation	NOUN
admet-24	188	13	)	)	PUNCT
admet-24	188	14	in	in	ADP
admet-24	188	15	the	the	DET
admet-24	188	16	case	case	NOUN
admet-24	188	17	of	of	ADP
admet-24	188	18	a	a	DET
admet-24	188	19	diprotic	diprotic	ADJ
admet-24	188	20	amphoteric	amphoteric	ADJ
admet-24	188	21	drug	drug	NOUN
admet-24	188	22	,	,	PUNCT
admet-24	188	23	a	a	DET
admet-24	188	24	saturated	saturate	VERB
admet-24	188	25	solution	solution	NOUN
admet-24	188	26	can	can	AUX
admet-24	188	27	be	be	AUX
admet-24	188	28	defined	define	VERB
admet-24	188	29	by	by	ADP
admet-24	188	30	the	the	DET
admet-24	188	31	equations	equation	NOUN
admet-24	188	32	and	and	CCONJ
admet-24	188	33	the	the	DET
admet-24	188	34	corresponding	corresponding	ADJ
admet-24	188	35	constants	constant	NOUN
admet-24	188	36	xh2	xh2	PROPN
admet-24	188	37	+	+	CCONJ
admet-24	188	38			CCONJ
admet-24	188	39	h+	h+	PUNCT
admet-24	189	1	+	+	CCONJ
admet-24	189	2	xh	xh	PROPN
admet-24	189	3	ka1	ka1	NOUN
admet-24	189	4	=	=	PUNCT
admet-24	190	1	[	[	X
admet-24	190	2	h+][xh	h+][xh	X
admet-24	190	3	]	]	X
admet-24	190	4	/	/	PUNCT
admet-24	191	1	[	[	X
admet-24	191	2	xh2	xh2	X
admet-24	191	3	+	+	X
admet-24	191	4	]	]	X
admet-24	191	5	(	(	PUNCT
admet-24	191	6	a1	a1	PROPN
admet-24	191	7	)	)	PUNCT
admet-24	191	8	xh	xh	PROPN
admet-24	191	9			X
admet-24	191	10	h+	h+	X
admet-24	192	1	+	+	CCONJ
admet-24	192	2	x	x	X
admet-24	192	3	–	–	PUNCT
admet-24	192	4	ka2	ka2	X
admet-24	192	5	=	=	PUNCT
admet-24	193	1	[	[	X
admet-24	193	2	h+][x	h+][x	NOUN
admet-24	193	3	–	–	PUNCT
admet-24	193	4	]	]	PUNCT
admet-24	193	5	/	/	PUNCT
admet-24	194	1	[	[	X
admet-24	194	2	xh	xh	X
admet-24	194	3	]	]	X
admet-24	194	4	(	(	PUNCT
admet-24	194	5	a2	a2	PROPN
admet-24	194	6	)	)	PUNCT
admet-24	194	7	hx(s	hx(s	NOUN
admet-24	194	8	)	)	PUNCT
admet-24	194	9			NOUN
admet-24	195	1	xh	xh	PROPN
admet-24	195	2	s0	s0	PROPN
admet-24	195	3	=	=	PUNCT
admet-24	196	1	[	[	X
admet-24	196	2	xh	xh	X
admet-24	196	3	]	]	X
admet-24	196	4	(	(	PUNCT
admet-24	196	5	a3	a3	NOUN
admet-24	196	6	)	)	PUNCT
admet-24	196	7	solubility	solubility	NOUN
admet-24	196	8	,	,	PUNCT
admet-24	196	9	s	s	AUX
admet-24	196	10	,	,	PUNCT
admet-24	196	11	at	at	ADP
admet-24	196	12	a	a	DET
admet-24	196	13	particular	particular	ADJ
admet-24	196	14	ph	ph	NOUN
admet-24	196	15	is	be	AUX
admet-24	196	16	defined	define	VERB
admet-24	196	17	as	as	ADP
admet-24	196	18	the	the	DET
admet-24	196	19	mass	mass	NOUN
admet-24	196	20	balance	balance	NOUN
admet-24	196	21	sum	sum	NOUN
admet-24	196	22	of	of	ADP
admet-24	196	23	the	the	DET
admet-24	196	24	concentrations	concentration	NOUN
admet-24	196	25	of	of	ADP
admet-24	196	26	all	all	PRON
admet-24	196	27	of	of	ADP
admet-24	196	28	the	the	DET
admet-24	196	29	species	specie	NOUN
admet-24	196	30	dissolved	dissolve	VERB
admet-24	196	31	in	in	ADP
admet-24	196	32	the	the	DET
admet-24	196	33	aqueous	aqueous	ADJ
admet-24	196	34	phase	phase	NOUN
admet-24	196	35	:	:	PUNCT
admet-24	196	36	s	s	VERB
admet-24	196	37	=	=	PUNCT
admet-24	197	1	[	[	X
admet-24	197	2	x	x	X
admet-24	197	3	–	–	PUNCT
admet-24	197	4	]	]	PUNCT
admet-24	197	5	+	+	CCONJ
admet-24	198	1	[	[	X
admet-24	198	2	xh	xh	X
admet-24	198	3	]	]	X
admet-24	198	4	+	+	CCONJ
admet-24	198	5	[	[	X
admet-24	198	6	xh2	xh2	X
admet-24	198	7	+	+	X
admet-24	198	8	]	]	X
admet-24	198	9	(	(	PUNCT
admet-24	198	10	a4	a4	NOUN
admet-24	198	11	)	)	PUNCT
admet-24	198	12	where	where	SCONJ
admet-24	198	13	the	the	DET
admet-24	198	14	square	square	ADJ
admet-24	198	15	brackets	bracket	NOUN
admet-24	198	16	denote	denote	VERB
admet-24	198	17	molar	molar	ADJ
admet-24	198	18	concentration	concentration	NOUN
admet-24	198	19	of	of	ADP
admet-24	198	20	species	specie	NOUN
admet-24	198	21	.	.	PUNCT
admet-24	199	1	the	the	DET
admet-24	199	2	above	above	ADJ
admet-24	199	3	equation	equation	NOUN
admet-24	199	4	can	can	AUX
admet-24	199	5	be	be	AUX
admet-24	199	6	transformed	transform	VERB
admet-24	199	7	into	into	ADP
admet-24	199	8	an	an	DET
admet-24	199	9	expression	expression	NOUN
admet-24	199	10	containing	contain	VERB
admet-24	199	11	only	only	ADJ
admet-24	199	12	constants	constant	NOUN
admet-24	199	13	and	and	CCONJ
admet-24	200	1	[	[	X
admet-24	200	2	h+	h+	X
admet-24	200	3	]	]	X
admet-24	200	4	(	(	PUNCT
admet-24	200	5	as	as	ADP
admet-24	200	6	the	the	DET
admet-24	200	7	only	only	ADJ
admet-24	200	8	variable	variable	NOUN
admet-24	200	9	)	)	PUNCT
admet-24	200	10	,	,	PUNCT
admet-24	200	11	by	by	ADP
admet-24	200	12	substituting	substitute	VERB
admet-24	200	13	the	the	DET
admet-24	200	14	ionization	ionization	NOUN
admet-24	200	15	and	and	CCONJ
admet-24	200	16	solubility	solubility	NOUN
admet-24	200	17	eqs	eqs	PROPN
admet-24	200	18	.	.	PUNCT
admet-24	200	19	a1	a1	NOUN
admet-24	200	20	-	-	PUNCT
admet-24	200	21	a3	a3	NOUN
admet-24	200	22	into	into	ADP
admet-24	200	23	eq	eq	NOUN
admet-24	200	24	.	.	PROPN
admet-24	200	25	a4	a4	NOUN
admet-24	200	26	.	.	PUNCT
admet-24	201	1	logs	log	NOUN
admet-24	201	2	=	=	SYM
admet-24	202	1	log(ka1/([xh][h+	log(ka1/([xh][h+	PROPN
admet-24	202	2	]	]	PUNCT
admet-24	202	3	)	)	PUNCT
admet-24	203	1	[	[	X
admet-24	203	2	xh	xh	X
admet-24	203	3	]	]	X
admet-24	204	1	[	[	X
admet-24	204	2	h+	h+	X
admet-24	204	3	]	]	X
admet-24	204	4	/ka1	/ka1	PUNCT
admet-24	205	1	+	+	PUNCT
admet-24	206	1	[	[	X
admet-24	206	2	xh	xh	X
admet-24	206	3	]	]	X
admet-24	206	4	+	+	CCONJ
admet-24	206	5	[	[	X
admet-24	206	6	xh][h+	xh][h+	X
admet-24	206	7	]	]	X
admet-24	206	8	/	/	SYM
admet-24	206	9	ka1	ka1	ADJ
admet-24	206	10	)	)	PUNCT
admet-24	206	11	=	=	SYM
admet-24	206	12	log[xh	log[xh	NOUN
admet-24	206	13	]	]	X
admet-24	206	14	+	+	PUNCT
admet-24	206	15	log(ka2	log(ka2	NOUN
admet-24	206	16	/	/	PUNCT
admet-24	207	1	[	[	X
admet-24	207	2	h+	h+	X
admet-24	207	3	]	]	X
admet-24	207	4	+	+	CCONJ
admet-24	207	5	1	1	NUM
admet-24	207	6	+	+	CCONJ
admet-24	207	7	[	[	X
admet-24	207	8	h+	h+	X
admet-24	207	9	]	]	X
admet-24	207	10	/	/	SYM
admet-24	207	11	ka1	ka1	NOUN
admet-24	207	12	)	)	PUNCT
admet-24	207	13	=	=	PUNCT
admet-24	207	14	logs0	logs0	NOUN
admet-24	208	1	+	+	PUNCT
admet-24	208	2	log(1	log(1	NOUN
admet-24	208	3	+	+	CCONJ
admet-24	208	4	10	10	NUM
admet-24	208	5	–	–	PUNCT
admet-24	208	6	pka2+ph	pka2+ph	PROPN
admet-24	208	7	+10+pka1	+10+pka1	PROPN
admet-24	208	8	–	–	PUNCT
admet-24	208	9	ph	ph	NOUN
admet-24	208	10	)	)	PUNCT
admet-24	208	11	(	(	PUNCT
admet-24	208	12	a5	a5	PROPN
admet-24	208	13	)	)	PUNCT
admet-24	208	14	eq	eq	NOUN
admet-24	208	15	.	.	PUNCT
admet-24	209	1	a5	a5	PROPN
admet-24	209	2	is	be	AUX
admet-24	209	3	often	often	ADV
admet-24	209	4	called	call	VERB
admet-24	209	5	the	the	DET
admet-24	209	6	henderson	henderson	PROPN
admet-24	209	7	-	-	PUNCT
admet-24	209	8	hasselbalch	hasselbalch	PROPN
admet-24	209	9	(	(	PUNCT
admet-24	209	10	hh	hh	NOUN
admet-24	209	11	)	)	PUNCT
admet-24	209	12	equation	equation	NOUN
admet-24	209	13	for	for	ADP
admet-24	209	14	a	a	DET
admet-24	209	15	diprotic	diprotic	ADJ
admet-24	209	16	ampholyte	ampholyte	NOUN
admet-24	209	17	,	,	PUNCT
admet-24	209	18	and	and	CCONJ
admet-24	209	19	describes	describe	VERB
admet-24	209	20	a	a	DET
admet-24	209	21	u	u	NOUN
admet-24	209	22	-	-	ADJ
admet-24	209	23	shaped	shape	VERB
admet-24	209	24	logs	log	NOUN
admet-24	209	25	–	–	PUNCT
admet-24	209	26	ph	ph	NOUN
admet-24	209	27	curve	curve	NOUN
admet-24	209	28	.	.	PUNCT
admet-24	210	1	at	at	ADP
admet-24	210	2	the	the	DET
admet-24	210	3	low	low	ADJ
admet-24	210	4	-	-	PUNCT
admet-24	210	5	ph	ph	NOUN
admet-24	210	6	bend	bend	NOUN
admet-24	210	7	in	in	ADP
admet-24	210	8	the	the	DET
admet-24	210	9	logs	log	NOUN
admet-24	210	10	–	–	PUNCT
admet-24	210	11	ph	ph	NOUN
admet-24	210	12	curve	curve	NOUN
admet-24	210	13	,	,	PUNCT
admet-24	210	14	the	the	DET
admet-24	210	15	ph	ph	NOUN
admet-24	210	16	equals	equal	VERB
admet-24	210	17	the	the	DET
admet-24	210	18	pka1	pka1	NOUN
admet-24	210	19	;	;	PUNCT
admet-24	210	20	at	at	ADP
admet-24	210	21	the	the	DET
admet-24	210	22	other	other	ADJ
admet-24	210	23	bend	bend	NOUN
admet-24	210	24	,	,	PUNCT
admet-24	210	25	ph	ph	NOUN
admet-24	210	26	equals	equal	VERB
admet-24	210	27	the	the	DET
admet-24	210	28	pka2	pka2	PROPN
admet-24	210	29	.	.	PUNCT
admet-24	211	1	salt	salt	NOUN
admet-24	211	2	precipitation	precipitation	NOUN
admet-24	211	3	of	of	ADP
admet-24	211	4	diprotic	diprotic	ADJ
admet-24	211	5	amphoteric	amphoteric	ADJ
admet-24	211	6	drug	drug	NOUN
admet-24	211	7	,	,	PUNCT
admet-24	211	8	xh	xh	PROPN
admet-24	211	9	admet	admet	PROPN
admet-24	211	10	&	&	CCONJ
admet-24	211	11	dmpk	dmpk	PROPN
admet-24	211	12	1(4	1(4	NUM
admet-24	211	13	)	)	PUNCT
admet-24	211	14	(	(	PUNCT
admet-24	211	15	2013	2013	NUM
admet-24	211	16	)	)	PUNCT
admet-24	211	17	48	48	NUM
admet-24	211	18	-	-	SYM
admet-24	211	19	62	62	NUM
admet-24	211	20	novel	novel	NOUN
admet-24	211	21	method	method	NOUN
admet-24	211	22	of	of	ADP
admet-24	211	23	salt	salt	NOUN
admet-24	211	24	solubility	solubility	NOUN
admet-24	211	25	analysis	analysis	NOUN
admet-24	211	26	doi	doi	NOUN
admet-24	211	27	:	:	PUNCT
admet-24	211	28	10.5599	10.5599	NUM
admet-24	211	29	/	/	SYM
admet-24	211	30	admet.1.4.24	admet.1.4.24	NOUN
admet-24	211	31	59	59	NUM
admet-24	211	32	eq	eq	NOUN
admet-24	211	33	.	.	PUNCT
admet-24	212	1	a5	a5	PROPN
admet-24	212	2	considers	consider	VERB
admet-24	212	3	only	only	ADV
admet-24	212	4	one	one	NUM
admet-24	212	5	precipitate	precipitate	NOUN
admet-24	212	6	,	,	PUNCT
admet-24	212	7	that	that	PRON
admet-24	212	8	of	of	ADP
admet-24	212	9	the	the	DET
admet-24	212	10	uncharged	uncharged	ADJ
admet-24	212	11	species	specie	NOUN
admet-24	212	12	xh	xh	PROPN
admet-24	212	13	,	,	PUNCT
admet-24	212	14	defining	define	VERB
admet-24	212	15	the	the	DET
admet-24	212	16	“	"	PUNCT
admet-24	212	17	intrinsic	intrinsic	ADJ
admet-24	212	18	solubility	solubility	NOUN
admet-24	212	19	”	"	PUNCT
admet-24	212	20	concentration	concentration	NOUN
admet-24	212	21	,	,	PUNCT
admet-24	212	22	s0	s0	PROPN
admet-24	212	23	.	.	PUNCT
admet-24	213	1	if	if	SCONJ
admet-24	213	2	the	the	DET
admet-24	213	3	solubility	solubility	NOUN
admet-24	213	4	experiment	experiment	NOUN
admet-24	213	5	were	be	AUX
admet-24	213	6	carried	carry	VERB
admet-24	213	7	out	out	ADP
admet-24	213	8	as	as	ADP
admet-24	213	9	an	an	DET
admet-24	213	10	acid	acid	NOUN
admet-24	213	11	-	-	PUNCT
admet-24	213	12	base	base	NOUN
admet-24	213	13	(	(	PUNCT
admet-24	213	14	hcl	hcl	PROPN
admet-24	213	15	/	/	SYM
admet-24	213	16	naoh	naoh	NOUN
admet-24	213	17	)	)	PUNCT
admet-24	213	18	titration	titration	NOUN
admet-24	213	19	,	,	PUNCT
admet-24	213	20	over	over	ADP
admet-24	213	21	a	a	DET
admet-24	213	22	wide	wide	ADJ
admet-24	213	23	range	range	NOUN
admet-24	213	24	ph	ph	VERB
admet-24	213	25	<	<	X
admet-24	213	26	<	<	X
admet-24	213	27	pka1	pka1	PROPN
admet-24	213	28	to	to	PART
admet-24	213	29	ph	ph	VERB
admet-24	213	30	>	>	PUNCT
admet-24	213	31	>	>	X
admet-24	213	32	pka2	pka2	PROPN
admet-24	213	33	,	,	PUNCT
admet-24	213	34	with	with	SCONJ
admet-24	213	35	enough	enough	ADJ
admet-24	213	36	excess	excess	ADJ
admet-24	213	37	compound	compound	NOUN
admet-24	213	38	added	add	VERB
admet-24	213	39	that	that	SCONJ
admet-24	213	40	the	the	DET
admet-24	213	41	solubility	solubility	NOUN
admet-24	213	42	products	product	NOUN
admet-24	213	43	of	of	ADP
admet-24	213	44	the	the	DET
admet-24	213	45	salts	salt	NOUN
admet-24	213	46	xh2	xh2	NOUN
admet-24	213	47	+	+	CCONJ
admet-24	213	48	cl	cl	INTJ
admet-24	213	49	–	–	PUNCT
admet-24	213	50	(	(	PUNCT
admet-24	213	51	s	s	X
admet-24	213	52	)	)	PUNCT
admet-24	213	53	and	and	CCONJ
admet-24	213	54	na	na	ADP
admet-24	213	55	+	+	NOUN
admet-24	213	56	x	x	X
admet-24	213	57	–	–	PUNCT
admet-24	213	58	(	(	PUNCT
admet-24	213	59	s	s	X
admet-24	213	60	)	)	PUNCT
admet-24	213	61	are	be	AUX
admet-24	213	62	exceeded	exceed	VERB
admet-24	213	63	,	,	PUNCT
admet-24	213	64	then	then	ADV
admet-24	213	65	the	the	DET
admet-24	213	66	curve	curve	NOUN
admet-24	213	67	would	would	AUX
admet-24	213	68	have	have	VERB
admet-24	213	69	regions	region	NOUN
admet-24	213	70	at	at	ADP
admet-24	213	71	low	low	ADJ
admet-24	213	72	ph	ph	ADJ
admet-24	213	73	and	and	CCONJ
admet-24	213	74	high	high	ADJ
admet-24	213	75	ph	ph	NOUN
admet-24	213	76	that	that	PRON
admet-24	213	77	would	would	AUX
admet-24	213	78	not	not	PART
admet-24	213	79	behave	behave	VERB
admet-24	213	80	as	as	SCONJ
admet-24	213	81	indicated	indicate	VERB
admet-24	213	82	by	by	ADP
admet-24	213	83	the	the	DET
admet-24	213	84	hh	hh	PROPN
admet-24	213	85	equation	equation	NOUN
admet-24	213	86	.	.	PUNCT
admet-24	214	1	to	to	PART
admet-24	214	2	describe	describe	VERB
admet-24	214	3	these	these	DET
admet-24	214	4	processes	process	NOUN
admet-24	214	5	,	,	PUNCT
admet-24	214	6	two	two	NUM
admet-24	214	7	additional	additional	ADJ
admet-24	214	8	solubility	solubility	NOUN
admet-24	214	9	equations	equation	NOUN
admet-24	214	10	need	need	VERB
admet-24	214	11	to	to	PART
admet-24	214	12	be	be	AUX
admet-24	214	13	added	add	VERB
admet-24	214	14	to	to	ADP
admet-24	214	15	eqs	eqs	PROPN
admet-24	214	16	.	.	PUNCT
admet-24	214	17	a1	a1	PROPN
admet-24	214	18	-	-	PUNCT
admet-24	214	19	a3	a3	NOUN
admet-24	214	20	:	:	PUNCT
admet-24	214	21	xh2	xh2	NOUN
admet-24	214	22	+	+	CCONJ
admet-24	214	23	cl	cl	INTJ
admet-24	214	24	–	–	PUNCT
admet-24	214	25	(	(	PUNCT
admet-24	214	26	s	s	NOUN
admet-24	214	27	)	)	PUNCT
admet-24	214	28			NOUN
admet-24	215	1	xh2	xh2	NOUN
admet-24	215	2	+	+	CCONJ
admet-24	215	3	+	+	CCONJ
admet-24	215	4	cl	cl	NOUN
admet-24	215	5	–	–	PUNCT
admet-24	215	6	ksp1	ksp1	NOUN
admet-24	215	7	=	=	PUNCT
admet-24	216	1	[	[	X
admet-24	216	2	xh2	xh2	X
admet-24	216	3	+	+	X
admet-24	216	4	]	]	PUNCT
admet-24	216	5	[	[	X
admet-24	216	6	cl	cl	NOUN
admet-24	216	7	–	–	PUNCT
admet-24	216	8	]	]	PUNCT
admet-24	216	9	(	(	PUNCT
admet-24	216	10	a6	a6	NOUN
admet-24	216	11	)	)	PUNCT
admet-24	216	12	na	na	PART
admet-24	217	1	+	+	NOUN
admet-24	217	2	x	x	X
admet-24	217	3	–	–	PUNCT
admet-24	217	4	(	(	PUNCT
admet-24	217	5	s	s	NOUN
admet-24	217	6	)	)	PUNCT
admet-24	217	7			NOUN
admet-24	217	8	na	na	ADP
admet-24	217	9	+	+	CCONJ
admet-24	217	10	+	+	CCONJ
admet-24	217	11	x	x	X
admet-24	217	12	–	–	PUNCT
admet-24	217	13	ksp2	ksp2	NOUN
admet-24	218	1	=	=	PUNCT
admet-24	219	1	[	[	X
admet-24	219	2	na	na	X
admet-24	219	3	+	+	NOUN
admet-24	219	4	]	]	PUNCT
admet-24	219	5	[	[	X
admet-24	219	6	x	x	X
admet-24	219	7	–	–	PUNCT
admet-24	219	8	]	]	PUNCT
admet-24	219	9	(	(	PUNCT
admet-24	219	10	a7	a7	ADJ
admet-24	219	11	)	)	PUNCT
admet-24	219	12	hydrochloride	hydrochloride	NOUN
admet-24	219	13	salt	salt	NOUN
admet-24	219	14	of	of	ADP
admet-24	219	15	the	the	DET
admet-24	219	16	drug	drug	NOUN
admet-24	219	17	,	,	PUNCT
admet-24	219	18	xh2	xh2	PROPN
admet-24	219	19	+	+	PROPN
admet-24	219	20	cl–(s	cl–(s	NOUN
admet-24	219	21	)	)	PUNCT
admet-24	219	22	if	if	SCONJ
admet-24	219	23	enough	enough	ADJ
admet-24	219	24	compound	compound	NOUN
admet-24	219	25	is	be	AUX
admet-24	219	26	added	add	VERB
admet-24	219	27	to	to	ADP
admet-24	219	28	the	the	DET
admet-24	219	29	suspension	suspension	NOUN
admet-24	219	30	and	and	CCONJ
admet-24	219	31	the	the	DET
admet-24	219	32	ph	ph	NOUN
admet-24	219	33	is	be	AUX
admet-24	219	34	gradually	gradually	ADV
admet-24	219	35	lowered	lower	VERB
admet-24	219	36	,	,	PUNCT
admet-24	219	37	well	well	ADV
admet-24	219	38	below	below	ADP
admet-24	219	39	pka1	pka1	PROPN
admet-24	219	40	,	,	PUNCT
admet-24	219	41	at	at	ADP
admet-24	219	42	a	a	DET
admet-24	219	43	critical	critical	ADJ
admet-24	219	44	ph	ph	NOUN
admet-24	219	45	point	point	NOUN
admet-24	219	46	,	,	PUNCT
admet-24	219	47	called	call	VERB
admet-24	219	48	pka1	pka1	PROPN
admet-24	219	49	gibbs	gibbs	PROPN
admet-24	220	1	[	[	X
admet-24	220	2	30,31	30,31	PROPN
admet-24	220	3	]	]	PUNCT
admet-24	220	4	,	,	PUNCT
admet-24	220	5	the	the	DET
admet-24	220	6	hh	hh	PROPN
admet-24	220	7	equation	equation	NOUN
admet-24	220	8	is	be	AUX
admet-24	220	9	replaced	replace	VERB
admet-24	220	10	by	by	ADP
admet-24	220	11	an	an	DET
admet-24	220	12	approximately	approximately	ADV
admet-24	220	13	horizontal	horizontal	ADJ
admet-24	220	14	line	line	NOUN
admet-24	220	15	.	.	PUNCT
admet-24	221	1	in	in	ADP
admet-24	221	2	the	the	DET
admet-24	221	3	salt	salt	NOUN
admet-24	221	4	solubility	solubility	NOUN
admet-24	221	5	region	region	NOUN
admet-24	221	6	,	,	PUNCT
admet-24	221	7	ph	ph	X
admet-24	221	8	<	<	X
admet-24	221	9	pka1	pka1	PROPN
admet-24	221	10	gibbs	gibbs	PROPN
admet-24	221	11	,	,	PUNCT
admet-24	221	12	eq	eq	NOUN
admet-24	221	13	.	.	NOUN
admet-24	221	14	a4	a4	NOUN
admet-24	221	15	still	still	ADV
admet-24	221	16	holds	hold	VERB
admet-24	221	17	,	,	PUNCT
admet-24	221	18	but	but	CCONJ
admet-24	221	19	[	[	X
admet-24	221	20	xh2	xh2	X
admet-24	221	21	+	+	CCONJ
admet-24	221	22	]	]	PUNCT
admet-24	221	23	becomes	become	VERB
admet-24	221	24	constant	constant	ADJ
admet-24	221	25	,	,	PUNCT
admet-24	221	26	instead	instead	ADV
admet-24	221	27	of	of	ADP
admet-24	221	28	[	[	X
admet-24	221	29	xh	xh	X
admet-24	221	30	]	]	X
admet-24	221	31	.	.	PUNCT
admet-24	222	1	eq	eq	NOUN
admet-24	222	2	.	.	PUNCT
admet-24	223	1	a5	a5	PROPN
admet-24	223	2	can	can	AUX
admet-24	223	3	be	be	AUX
admet-24	223	4	modified	modify	VERB
admet-24	223	5	(	(	PUNCT
admet-24	223	6	using	use	VERB
admet-24	223	7	eqs	eqs	PROPN
admet-24	223	8	.	.	PUNCT
admet-24	223	9	a1	a1	PROPN
admet-24	223	10	,	,	PUNCT
admet-24	223	11	a2	a2	PROPN
admet-24	223	12	and	and	CCONJ
admet-24	223	13	a6	a6	NOUN
admet-24	223	14	)	)	PUNCT
admet-24	223	15	to	to	PART
admet-24	223	16	reflect	reflect	VERB
admet-24	223	17	this	this	PRON
admet-24	223	18	.	.	PUNCT
admet-24	224	1	logs	log	NOUN
admet-24	224	2	=	=	SYM
admet-24	225	1	log(ka2	log(ka2	PROPN
admet-24	225	2	ka1	ka1	VERB
admet-24	226	1	[	[	X
admet-24	226	2	xh2	xh2	X
admet-24	227	1	+	+	X
admet-24	227	2	]	]	X
admet-24	227	3	/	/	PUNCT
admet-24	228	1	[	[	X
admet-24	228	2	h+]2	h+]2	X
admet-24	228	3	+	+	CCONJ
admet-24	228	4	ka1	ka1	VERB
admet-24	229	1	[	[	X
admet-24	229	2	xh2	xh2	X
admet-24	229	3	+	+	X
admet-24	229	4	]	]	X
admet-24	229	5	/	/	SYM
admet-24	230	1	[	[	X
admet-24	230	2	h+	h+	X
admet-24	230	3	]	]	X
admet-24	230	4	+	+	CCONJ
admet-24	231	1	[	[	X
admet-24	231	2	xh2	xh2	X
admet-24	231	3	+	+	X
admet-24	231	4	]	]	X
admet-24	231	5	)	)	PUNCT
admet-24	232	1	=	=	PUNCT
admet-24	232	2	log[xh2	log[xh2	X
admet-24	233	1	+	+	X
admet-24	233	2	]	]	PUNCT
admet-24	233	3	+	+	PUNCT
admet-24	233	4	log(1	log(1	NOUN
admet-24	233	5	+	+	CCONJ
admet-24	233	6	10	10	NUM
admet-24	233	7	–	–	PUNCT
admet-24	233	8	pka1	pka1	PROPN
admet-24	233	9	–	–	PUNCT
admet-24	233	10	pka2	pka2	PROPN
admet-24	233	11	+	+	ADJ
admet-24	233	12	2ph	2ph	ADJ
admet-24	233	13	+10	+10	NOUN
admet-24	233	14	–	–	PUNCT
admet-24	233	15	pka1+ph	pka1+ph	NOUN
admet-24	233	16	)	)	PUNCT
admet-24	234	1	=	=	SYM
admet-24	234	2	logksp1	logksp1	NOUN
admet-24	234	3	–	–	PUNCT
admet-24	234	4	log[cl	log[cl	PROPN
admet-24	234	5	–	–	PUNCT
admet-24	234	6	]	]	PUNCT
admet-24	235	1	+	+	PUNCT
admet-24	235	2	log(1	log(1	NOUN
admet-24	235	3	+	+	CCONJ
admet-24	235	4	10	10	NUM
admet-24	235	5	–	–	PUNCT
admet-24	235	6	pka1	pka1	PROPN
admet-24	235	7	–	–	PUNCT
admet-24	235	8	pka2	pka2	PROPN
admet-24	235	9	+	+	ADJ
admet-24	235	10	2ph	2ph	ADJ
admet-24	235	11	+10	+10	NOUN
admet-24	235	12	–	–	PUNCT
admet-24	235	13	pka1+ph	pka1+ph	NOUN
admet-24	235	14	)	)	PUNCT
admet-24	235	15	(	(	PUNCT
admet-24	235	16	a8	a8	PROPN
admet-24	235	17	)	)	PUNCT
admet-24	235	18	for	for	ADP
admet-24	235	19	ph	ph	NOUN
admet-24	235	20	<	<	X
admet-24	235	21	<	<	X
admet-24	235	22	pka1	pka1	PROPN
admet-24	235	23	,	,	PUNCT
admet-24	235	24	the	the	DET
admet-24	235	25	right	right	ADV
admet-24	235	26	-	-	PUNCT
admet-24	235	27	most	most	ADV
admet-24	235	28	logarithmic	logarithmic	ADJ
admet-24	235	29	term	term	NOUN
admet-24	235	30	in	in	ADP
admet-24	235	31	eq	eq	NOUN
admet-24	235	32	.	.	PUNCT
admet-24	236	1	a8	a8	PROPN
admet-24	236	2	becomes	become	VERB
admet-24	236	3	vanishingly	vanishingly	ADV
admet-24	236	4	small	small	ADJ
admet-24	236	5	,	,	PUNCT
admet-24	236	6	and	and	CCONJ
admet-24	236	7	cationic	cationic	ADJ
admet-24	236	8	-	-	PUNCT
admet-24	236	9	drug	drug	NOUN
admet-24	236	10	conditional	conditional	ADJ
admet-24	236	11	solubility	solubility	NOUN
admet-24	236	12	is	be	AUX
admet-24	236	13	described	describe	VERB
admet-24	236	14	by	by	ADP
admet-24	236	15	s(+	s(+	PROPN
admet-24	236	16	)	)	PUNCT
admet-24	237	1	=	=	PUNCT
admet-24	238	1	[	[	X
admet-24	238	2	xh2	xh2	X
admet-24	238	3	+	+	X
admet-24	238	4	]	]	PUNCT
admet-24	238	5	=	=	PUNCT
admet-24	238	6	ksp1	ksp1	PROPN
admet-24	238	7	/[cl	/[cl	PUNCT
admet-24	238	8	–	–	PUNCT
admet-24	238	9	]	]	PUNCT
admet-24	238	10	.	.	PUNCT
admet-24	239	1	eq	eq	X
admet-24	239	2	.	.	PUNCT
admet-24	239	3	a8	a8	PROPN
admet-24	239	4	largely	largely	ADV
admet-24	239	5	describes	describe	VERB
admet-24	239	6	a	a	DET
admet-24	239	7	horizontal	horizontal	ADJ
admet-24	239	8	line	line	NOUN
admet-24	239	9	.	.	PUNCT
admet-24	240	1	however	however	ADV
admet-24	240	2	,	,	PUNCT
admet-24	240	3	since	since	SCONJ
admet-24	240	4	the	the	DET
admet-24	240	5	hcl	hcl	PROPN
admet-24	240	6	titrant	titrant	NOUN
admet-24	240	7	both	both	PRON
admet-24	240	8	dilutes	dilute	VERB
admet-24	240	9	the	the	DET
admet-24	240	10	solution	solution	NOUN
admet-24	240	11	and	and	CCONJ
admet-24	240	12	elevates	elevate	VERB
admet-24	240	13	the	the	DET
admet-24	240	14	cl	cl	NOUN
admet-24	240	15	–	–	PUNCT
admet-24	240	16	,	,	PUNCT
admet-24	240	17	the	the	DET
admet-24	240	18	horizontal	horizontal	ADJ
admet-24	240	19	line	line	NOUN
admet-24	240	20	curves	curve	VERB
admet-24	240	21	downward	downward	ADV
admet-24	240	22	for	for	ADP
admet-24	240	23	ph	ph	NOUN
admet-24	240	24	<	<	X
admet-24	240	25	2	2	NUM
admet-24	240	26	,	,	PUNCT
admet-24	240	27	noted	note	VERB
admet-24	240	28	as	as	ADP
admet-24	240	29	the	the	DET
admet-24	240	30	chloride	chloride	NOUN
admet-24	240	31	“	"	PUNCT
admet-24	240	32	common	common	ADJ
admet-24	240	33	-	-	PUNCT
admet-24	240	34	ion	ion	NOUN
admet-24	240	35	”	"	PUNCT
admet-24	240	36	effect	effect	NOUN
admet-24	240	37	,	,	PUNCT
admet-24	240	38	according	accord	VERB
admet-24	240	39	to	to	ADP
admet-24	240	40	eq	eq	PROPN
admet-24	240	41	.	.	PUNCT
admet-24	241	1	a8	a8	PROPN
admet-24	241	2	.	.	PUNCT
admet-24	242	1	sodium	sodium	NOUN
admet-24	242	2	salt	salt	NOUN
admet-24	242	3	of	of	ADP
admet-24	242	4	the	the	DET
admet-24	242	5	drug	drug	NOUN
admet-24	242	6	,	,	PUNCT
admet-24	242	7	na	na	ADP
admet-24	242	8	+	+	NOUN
admet-24	242	9	x	x	X
admet-24	242	10	–	–	PUNCT
admet-24	242	11	(	(	PUNCT
admet-24	242	12	s	s	NOUN
admet-24	242	13	)	)	PUNCT
admet-24	242	14	in	in	ADP
admet-24	242	15	the	the	DET
admet-24	242	16	presence	presence	NOUN
admet-24	242	17	of	of	ADP
admet-24	242	18	a	a	DET
admet-24	242	19	large	large	ADJ
admet-24	242	20	excess	excess	NOUN
admet-24	242	21	of	of	ADP
admet-24	242	22	compound	compound	NOUN
admet-24	242	23	in	in	ADP
admet-24	242	24	alkaline	alkaline	NOUN
admet-24	242	25	ph	ph	PROPN
admet-24	242	26	>	>	PUNCT
admet-24	242	27	>	>	X
admet-24	242	28	pka2	pka2	PROPN
admet-24	242	29	,	,	PUNCT
admet-24	242	30	at	at	ADP
admet-24	242	31	the	the	DET
admet-24	242	32	second	second	ADJ
admet-24	242	33	critical	critical	ADJ
admet-24	242	34	ph	ph	NOUN
admet-24	242	35	point	point	NOUN
admet-24	242	36	,	,	PUNCT
admet-24	242	37	pka2	pka2	PROPN
admet-24	242	38	gibbs	gibbs	PROPN
admet-24	242	39	,	,	PUNCT
admet-24	242	40	the	the	DET
admet-24	242	41	hh	hh	PROPN
admet-24	242	42	equation	equation	NOUN
admet-24	242	43	is	be	AUX
admet-24	242	44	replaced	replace	VERB
admet-24	242	45	by	by	ADP
admet-24	242	46	another	another	DET
admet-24	242	47	approximately	approximately	ADV
admet-24	242	48	horizontal	horizontal	ADJ
admet-24	242	49	line	line	NOUN
admet-24	242	50	.	.	PUNCT
admet-24	243	1	in	in	ADP
admet-24	243	2	the	the	DET
admet-24	243	3	salt	salt	NOUN
admet-24	243	4	solubility	solubility	NOUN
admet-24	243	5	region	region	NOUN
admet-24	243	6	,	,	PUNCT
admet-24	243	7	ph	ph	PROPN
admet-24	243	8	>	>	X
admet-24	243	9	pka2	pka2	PROPN
admet-24	243	10	gibbs	gibbs	PROPN
admet-24	243	11	,	,	PUNCT
admet-24	243	12	eq	eq	NOUN
admet-24	243	13	.	.	NOUN
admet-24	243	14	a4	a4	NOUN
admet-24	243	15	still	still	ADV
admet-24	243	16	holds	hold	VERB
admet-24	243	17	,	,	PUNCT
admet-24	243	18	but	but	CCONJ
admet-24	243	19	[	[	X
admet-24	243	20	x	x	X
admet-24	243	21	–	–	PUNCT
admet-24	243	22	]	]	PUNCT
admet-24	243	23	becomes	become	VERB
admet-24	243	24	constant	constant	ADJ
admet-24	243	25	,	,	PUNCT
admet-24	243	26	while	while	SCONJ
admet-24	243	27	[	[	X
admet-24	243	28	xh	xh	X
admet-24	243	29	]	]	PUNCT
admet-24	243	30	and	and	CCONJ
admet-24	243	31	[	[	X
admet-24	243	32	xh2	xh2	X
admet-24	243	33	+	+	X
admet-24	243	34	]	]	X
admet-24	243	35	are	be	AUX
admet-24	243	36	variable	variable	ADJ
admet-24	243	37	.	.	PUNCT
admet-24	244	1	eq	eq	X
admet-24	244	2	.	.	PUNCT
admet-24	245	1	a5	a5	PROPN
admet-24	245	2	can	can	AUX
admet-24	245	3	be	be	AUX
admet-24	245	4	further	far	ADV
admet-24	245	5	modified	modify	VERB
admet-24	245	6	(	(	PUNCT
admet-24	245	7	using	use	VERB
admet-24	245	8	eqs	eqs	PROPN
admet-24	245	9	.	.	PUNCT
admet-24	245	10	a1	a1	PROPN
admet-24	245	11	,	,	PUNCT
admet-24	245	12	a2	a2	PROPN
admet-24	245	13	and	and	CCONJ
admet-24	245	14	a7	a7	PROPN
admet-24	245	15	)	)	PUNCT
admet-24	245	16	as	as	ADP
admet-24	245	17	logs	log	NOUN
admet-24	245	18	=	=	SYM
admet-24	245	19	log	log	NOUN
admet-24	245	20	(	(	PUNCT
admet-24	245	21	[	[	X
admet-24	245	22	x	x	X
admet-24	245	23	–	–	PUNCT
admet-24	245	24	]	]	PUNCT
admet-24	245	25	+	+	CCONJ
admet-24	246	1	[	[	X
admet-24	246	2	x–][h+	x–][h+	X
admet-24	246	3	]	]	X
admet-24	246	4	/	/	SYM
admet-24	246	5	ka2	ka2	NOUN
admet-24	247	1	+	+	CCONJ
admet-24	248	1	[	[	X
admet-24	248	2	x	x	X
admet-24	248	3	–	–	PUNCT
admet-24	248	4	]	]	PUNCT
admet-24	248	5	[	[	X
admet-24	248	6	h+]2	h+]2	NOUN
admet-24	248	7	/	/	SYM
admet-24	248	8	(	(	PUNCT
admet-24	248	9	ka1ka2	ka1ka2	NOUN
admet-24	248	10	)	)	PUNCT
admet-24	248	11	)	)	PUNCT
admet-24	249	1	=	=	PUNCT
admet-24	249	2	log[x-	log[x-	X
admet-24	249	3	]	]	X
admet-24	249	4	+	+	PUNCT
admet-24	249	5	log(1	log(1	NOUN
admet-24	249	6	+	+	CCONJ
admet-24	249	7	10	10	NUM
admet-24	249	8	+	+	NUM
admet-24	249	9	pka1+pka2–2ph	pka1+pka2–2ph	NOUN
admet-24	249	10	+10	+10	NOUN
admet-24	249	11	–	–	PUNCT
admet-24	249	12	pka2+ph	pka2+ph	X
admet-24	249	13	)	)	PUNCT
admet-24	249	14	=	=	SYM
admet-24	249	15	logksp2	logksp2	NOUN
admet-24	249	16	–	–	PUNCT
admet-24	249	17	log[na+	log[na+	X
admet-24	249	18	]	]	PUNCT
admet-24	249	19	+	+	NUM
admet-24	249	20	log(1	log(1	NOUN
admet-24	249	21	+	+	CCONJ
admet-24	249	22	10	10	NUM
admet-24	249	23	+	+	NUM
admet-24	249	24	pka1+pka2–2ph	pka1+pka2–2ph	NOUN
admet-24	249	25	+10	+10	NOUN
admet-24	249	26	–	–	PUNCT
admet-24	249	27	pka2+ph	pka2+ph	X
admet-24	249	28	)	)	PUNCT
admet-24	249	29	(	(	PUNCT
admet-24	249	30	a9	a9	PROPN
admet-24	249	31	)	)	PUNCT
admet-24	249	32	for	for	ADP
admet-24	249	33	ph	ph	NOUN
admet-24	249	34	>	>	PUNCT
admet-24	249	35	>	>	X
admet-24	249	36	pka2	pka2	PROPN
admet-24	249	37	,	,	PUNCT
admet-24	249	38	the	the	DET
admet-24	249	39	right	right	ADV
admet-24	249	40	-	-	PUNCT
admet-24	249	41	most	most	ADV
admet-24	249	42	logarithmic	logarithmic	ADJ
admet-24	249	43	term	term	NOUN
admet-24	249	44	in	in	ADP
admet-24	249	45	eq	eq	ADP
admet-24	249	46	.	.	PUNCT
admet-24	249	47	a9	a9	PROPN
admet-24	249	48	becomes	become	VERB
admet-24	249	49	vanishingly	vanishingly	ADV
admet-24	249	50	small	small	ADJ
admet-24	249	51	,	,	PUNCT
admet-24	249	52	and	and	CCONJ
admet-24	249	53	conditional	conditional	ADJ
admet-24	249	54	anionic	anionic	ADJ
admet-24	249	55	-	-	PUNCT
admet-24	249	56	drug	drug	NOUN
admet-24	249	57	solubility	solubility	NOUN
admet-24	249	58	is	be	AUX
admet-24	249	59	described	describe	VERB
admet-24	249	60	by	by	ADP
admet-24	249	61	s	s	PROPN
admet-24	249	62	(	(	PUNCT
admet-24	249	63	–	–	PUNCT
admet-24	249	64	)	)	PUNCT
admet-24	249	65	=	=	PUNCT
admet-24	250	1	[	[	X
admet-24	250	2	x	x	X
admet-24	250	3	–	–	PUNCT
admet-24	250	4	]	]	PUNCT
admet-24	250	5	=	=	SYM
admet-24	250	6	ksp2	ksp2	NOUN
admet-24	250	7	/	/	PUNCT
admet-24	251	1	[	[	X
admet-24	251	2	na+	na+	X
admet-24	251	3	]	]	X
admet-24	251	4	.	.	PUNCT
admet-24	252	1	since	since	SCONJ
admet-24	252	2	the	the	DET
admet-24	252	3	naoh	naoh	NOUN
admet-24	252	4	titrant	titrant	NOUN
admet-24	252	5	both	both	PRON
admet-24	252	6	dilutes	dilute	VERB
admet-24	252	7	the	the	DET
admet-24	252	8	solution	solution	NOUN
admet-24	252	9	and	and	CCONJ
admet-24	252	10	raises	raise	VERB
admet-24	252	11	the	the	DET
admet-24	252	12	sodium	sodium	NOUN
admet-24	252	13	concentration	concentration	NOUN
admet-24	252	14	in	in	ADP
admet-24	252	15	solution	solution	NOUN
admet-24	252	16	,	,	PUNCT
admet-24	252	17	the	the	DET
admet-24	252	18	horizontal	horizontal	ADJ
admet-24	252	19	line	line	NOUN
admet-24	252	20	curves	curve	VERB
admet-24	252	21	downward	downward	ADV
admet-24	252	22	for	for	ADP
admet-24	252	23	ph	ph	PROPN
admet-24	252	24	>	>	X
admet-24	252	25	12	12	NUM
admet-24	252	26	,	,	PUNCT
admet-24	252	27	as	as	ADP
admet-24	252	28	a	a	DET
admet-24	252	29	result	result	NOUN
admet-24	252	30	of	of	ADP
admet-24	252	31	the	the	DET
admet-24	252	32	sodium	sodium	NOUN
admet-24	252	33	“	"	PUNCT
admet-24	252	34	common	common	ADJ
admet-24	252	35	-	-	PUNCT
admet-24	252	36	ion	ion	NOUN
admet-24	252	37	”	"	PUNCT
admet-24	252	38	effect	effect	NOUN
admet-24	252	39	,	,	PUNCT
admet-24	252	40	according	accord	VERB
admet-24	252	41	to	to	ADP
admet-24	252	42	eq	eq	PROPN
admet-24	252	43	.	.	PROPN
admet-24	252	44	a9	a9	PROPN
admet-24	252	45	.	.	PUNCT
admet-24	253	1	the	the	DET
admet-24	253	2	complete	complete	ADJ
admet-24	253	3	solubility	solubility	NOUN
admet-24	253	4	equation	equation	NOUN
admet-24	253	5	across	across	ADP
admet-24	253	6	the	the	DET
admet-24	253	7	whole	whole	ADJ
admet-24	253	8	ph	ph	ADJ
admet-24	253	9	range	range	NOUN
admet-24	253	10	,	,	PUNCT
admet-24	253	11	given	give	VERB
admet-24	253	12	enough	enough	ADJ
admet-24	253	13	compound	compound	NOUN
admet-24	253	14	excess	excess	NOUN
admet-24	253	15	,	,	PUNCT
admet-24	253	16	the	the	DET
admet-24	253	17	complete	complete	ADJ
admet-24	253	18	solubility	solubility	NOUN
admet-24	253	19	equation	equation	NOUN
admet-24	253	20	consists	consist	VERB
admet-24	253	21	of	of	ADP
admet-24	253	22	three	three	NUM
admet-24	253	23	segments	segment	NOUN
admet-24	253	24	:	:	PUNCT
admet-24	253	25	(	(	PUNCT
admet-24	253	26	a	a	X
admet-24	253	27	)	)	PUNCT
admet-24	253	28	conditional	conditional	ADJ
admet-24	253	29	hydrochloride	hydrochloride	NOUN
admet-24	253	30	salt	salt	NOUN
admet-24	253	31	region	region	NOUN
admet-24	253	32	,	,	PUNCT
admet-24	253	33	ph	ph	X
admet-24	253	34	<	<	X
admet-24	253	35	pka1	pka1	PROPN
admet-24	253	36	gibbs	gibbs	PROPN
admet-24	253	37	(	(	PUNCT
admet-24	253	38	eq	eq	NOUN
admet-24	253	39	.	.	PROPN
admet-24	253	40	a8	a8	PROPN
admet-24	253	41	)	)	PUNCT
admet-24	253	42	,	,	PUNCT
admet-24	253	43	(	(	PUNCT
admet-24	253	44	b	b	X
admet-24	253	45	)	)	PUNCT
admet-24	253	46	drug	drug	NOUN
admet-24	253	47	concentrationindependent	concentrationindependent	NOUN
admet-24	253	48	“	"	PUNCT
admet-24	253	49	hh	hh	PROPN
admet-24	253	50	”	"	PUNCT
admet-24	253	51	region	region	NOUN
admet-24	253	52	,	,	PUNCT
admet-24	253	53	pka2	pka2	PROPN
admet-24	253	54	gibbs	gibbs	PROPN
admet-24	253	55	>	>	X
admet-24	253	56	ph	ph	PROPN
admet-24	253	57	>	>	X
admet-24	253	58	pka1	pka1	PROPN
admet-24	253	59	gibbs	gibbs	PROPN
admet-24	253	60	(	(	PUNCT
admet-24	253	61	eq	eq	NOUN
admet-24	253	62	.	.	PUNCT
admet-24	253	63	a5	a5	PROPN
admet-24	253	64	)	)	PUNCT
admet-24	253	65	,	,	PUNCT
admet-24	253	66	and	and	CCONJ
admet-24	253	67	(	(	PUNCT
admet-24	253	68	c	c	X
admet-24	253	69	)	)	PUNCT
admet-24	253	70	conditional	conditional	ADJ
admet-24	253	71	sodium	sodium	NOUN
admet-24	253	72	salt	salt	NOUN
admet-24	253	73	region	region	NOUN
admet-24	253	74	,	,	PUNCT
admet-24	253	75	ph	ph	PROPN
admet-24	253	76	>	>	X
admet-24	253	77	pka2	pka2	PROPN
admet-24	253	78	gibbs	gibbs	PROPN
admet-24	253	79	(	(	PUNCT
admet-24	253	80	eq	eq	NOUN
admet-24	253	81	.	.	PUNCT
admet-24	253	82	(	(	PUNCT
admet-24	253	83	a9	a9	NOUN
admet-24	253	84	)	)	PUNCT
admet-24	253	85	)	)	PUNCT
admet-24	253	86	.	.	PUNCT
admet-24	254	1	gergely	gergely	ADV
admet-24	254	2	völgyi	völgyi	VERB
admet-24	254	3	et	et	PROPN
admet-24	254	4	al	al	PROPN
admet-24	254	5	.	.	PROPN
admet-24	254	6	admet	admet	PROPN
admet-24	254	7	&	&	CCONJ
admet-24	254	8	dmpk	dmpk	PROPN
admet-24	254	9	1(4	1(4	NUM
admet-24	254	10	)	)	PUNCT
admet-24	254	11	(	(	PUNCT
admet-24	254	12	2013	2013	NUM
admet-24	254	13	)	)	PUNCT
admet-24	254	14	48	48	NUM
admet-24	254	15	-	-	SYM
admet-24	254	16	62	62	NUM
admet-24	254	17	60	60	NUM
admet-24	254	18	gibbs	gibbs	PROPN
admet-24	254	19	pka	pka	PROPN
admet-24	254	20	values	value	NOUN
admet-24	254	21	at	at	ADP
admet-24	254	22	the	the	DET
admet-24	254	23	lower	low	ADJ
admet-24	254	24	ph	ph	NOUN
admet-24	254	25	=	=	NOUN
admet-24	254	26	pka1	pka1	PROPN
admet-24	254	27	gibbs	gibbs	PROPN
admet-24	254	28	,	,	PUNCT
admet-24	254	29	two	two	NUM
admet-24	254	30	solids	solid	NOUN
admet-24	254	31	co	co	NOUN
admet-24	254	32	-	-	NOUN
admet-24	254	33	precipitate	precipitate	ADJ
admet-24	254	34	:	:	PUNCT
admet-24	254	35	xh2	xh2	NOUN
admet-24	254	36	+	+	CCONJ
admet-24	254	37	cl	cl	INTJ
admet-24	254	38	–	–	PUNCT
admet-24	254	39	(	(	PUNCT
admet-24	254	40	s	s	NOUN
admet-24	254	41	)	)	PUNCT
admet-24	254	42	and	and	CCONJ
admet-24	254	43	xh(s	xh(s	NUM
admet-24	254	44	)	)	PUNCT
admet-24	254	45	.	.	PUNCT
admet-24	255	1	at	at	ADP
admet-24	255	2	the	the	DET
admet-24	255	3	higher	high	ADJ
admet-24	255	4	ph	ph	NOUN
admet-24	255	5	=	=	SYM
admet-24	255	6	pka2	pka2	PROPN
admet-24	255	7	gibbs	gibbs	PROPN
admet-24	255	8	,	,	PUNCT
admet-24	255	9	two	two	NUM
admet-24	255	10	different	different	ADJ
admet-24	255	11	solids	solid	NOUN
admet-24	255	12	co	co	NOUN
admet-24	255	13	-	-	NOUN
admet-24	255	14	precipitate	precipitate	ADJ
admet-24	255	15	:	:	PUNCT
admet-24	255	16	na+x–(s	na+x–(s	NUM
admet-24	255	17	)	)	PUNCT
admet-24	255	18	and	and	CCONJ
admet-24	255	19	xh(s	xh(s	NUM
admet-24	255	20	)	)	PUNCT
admet-24	255	21	.	.	PUNCT
admet-24	256	1	more	more	ADJ
admet-24	256	2	discussion	discussion	NOUN
admet-24	256	3	of	of	ADP
admet-24	256	4	the	the	DET
admet-24	256	5	topic	topic	NOUN
admet-24	256	6	may	may	AUX
admet-24	256	7	be	be	AUX
admet-24	256	8	found	find	VERB
admet-24	256	9	in	in	ADP
admet-24	256	10	the	the	DET
admet-24	256	11	literature	literature	NOUN
admet-24	257	1	[	[	X
admet-24	257	2	19,30,31	19,30,31	NUM
admet-24	257	3	]	]	PUNCT
admet-24	257	4	.	.	PUNCT
admet-24	258	1	cationic	cationic	ADJ
admet-24	258	2	,	,	PUNCT
admet-24	258	3	anionic	anionic	ADJ
admet-24	258	4	and	and	CCONJ
admet-24	258	5	neutral	neutral	ADJ
admet-24	258	6	self	self	NOUN
admet-24	258	7	-	-	PUNCT
admet-24	258	8	aggregate	aggregate	NOUN
admet-24	258	9	formations	formation	NOUN
admet-24	258	10	in	in	ADP
admet-24	258	11	concentrated	concentrated	ADJ
admet-24	258	12	drug	drug	NOUN
admet-24	258	13	solutions	solution	NOUN
admet-24	258	14	or	or	CCONJ
admet-24	258	15	in	in	ADP
admet-24	258	16	solutions	solution	NOUN
admet-24	258	17	containing	contain	VERB
admet-24	258	18	practically	practically	ADV
admet-24	258	19	insoluble	insoluble	ADJ
admet-24	258	20	drugs	drug	NOUN
admet-24	258	21	,	,	PUNCT
admet-24	258	22	oligomeric	oligomeric	ADJ
admet-24	258	23	species	specie	NOUN
admet-24	258	24	,	,	PUNCT
admet-24	258	25	xn	xn	PROPN
admet-24	258	26	n	n	CCONJ
admet-24	258	27	–	–	PUNCT
admet-24	258	28	,	,	PUNCT
admet-24	258	29	(	(	PUNCT
admet-24	258	30	xh2	xh2	NOUN
admet-24	258	31	+	+	CCONJ
admet-24	258	32	)	)	PUNCT
admet-24	259	1	n	n	X
admet-24	259	2	n+	n+	X
admet-24	259	3	,	,	PUNCT
admet-24	259	4	(	(	PUNCT
admet-24	259	5	xh)n	xh)n	PROPN
admet-24	259	6	,	,	PUNCT
admet-24	259	7	(	(	PUNCT
admet-24	259	8	xh.x	xh.x	NOUN
admet-24	259	9	–	–	PUNCT
admet-24	259	10	)	)	PUNCT
admet-24	259	11	n	n	CCONJ
admet-24	259	12	n	n	CCONJ
admet-24	259	13	,	,	PUNCT
admet-24	259	14	(	(	PUNCT
admet-24	259	15	xh.xh2	xh.xh2	PROPN
admet-24	260	1	+	+	CCONJ
admet-24	260	2	)	)	PUNCT
admet-24	261	1	n	n	PRON
admet-24	261	2	n+	n+	NUM
admet-24	261	3	,	,	PUNCT
admet-24	261	4	…	…	PUNCT
admet-24	261	5	,	,	PUNCT
admet-24	261	6	can	can	AUX
admet-24	261	7	form	form	VERB
admet-24	261	8	.	.	PUNCT
admet-24	262	1	these	these	PRON
admet-24	262	2	can	can	AUX
admet-24	262	3	characteristically	characteristically	ADV
admet-24	262	4	alter	alter	VERB
admet-24	262	5	the	the	DET
admet-24	262	6	shape	shape	NOUN
admet-24	262	7	of	of	ADP
admet-24	262	8	the	the	DET
admet-24	262	9	solubility	solubility	NOUN
admet-24	262	10	–	–	PUNCT
admet-24	262	11	ph	ph	NOUN
admet-24	262	12	profile	profile	NOUN
admet-24	262	13	.	.	PUNCT
admet-24	263	1	consequently	consequently	ADV
admet-24	263	2	,	,	PUNCT
admet-24	263	3	most	most	ADJ
admet-24	263	4	of	of	ADP
admet-24	263	5	eqs	eqs	PROPN
admet-24	263	6	.	.	PUNCT
admet-24	263	7	a1	a1	NOUN
admet-24	263	8	-	-	PUNCT
admet-24	263	9	a9	a9	NOUN
admet-24	263	10	would	would	AUX
admet-24	263	11	need	need	VERB
admet-24	263	12	to	to	PART
admet-24	263	13	be	be	AUX
admet-24	263	14	modified	modify	VERB
admet-24	263	15	to	to	PART
admet-24	263	16	accommodate	accommodate	VERB
admet-24	263	17	aggregation	aggregation	NOUN
admet-24	263	18	equilibria	equilibrium	NOUN
admet-24	263	19	.	.	PUNCT
admet-24	264	1	the	the	DET
admet-24	264	2	resultant	resultant	NOUN
admet-24	264	3	solubility	solubility	NOUN
admet-24	264	4	equations	equation	NOUN
admet-24	264	5	often	often	ADV
admet-24	264	6	become	become	VERB
admet-24	264	7	very	very	ADV
admet-24	264	8	complex	complex	ADJ
admet-24	264	9	,	,	PUNCT
admet-24	264	10	and	and	CCONJ
admet-24	264	11	not	not	PART
admet-24	264	12	all	all	DET
admet-24	264	13	combinations	combination	NOUN
admet-24	264	14	of	of	ADP
admet-24	264	15	possible	possible	ADJ
admet-24	264	16	species	specie	NOUN
admet-24	264	17	have	have	AUX
admet-24	264	18	had	have	VERB
admet-24	264	19	the	the	DET
admet-24	264	20	corresponding	corresponding	ADJ
admet-24	264	21	equations	equation	NOUN
admet-24	264	22	derived	derive	VERB
admet-24	264	23	.	.	PUNCT
admet-24	265	1	examples	example	NOUN
admet-24	265	2	of	of	ADP
admet-24	265	3	such	such	ADJ
admet-24	265	4	derivations	derivation	NOUN
admet-24	265	5	of	of	ADP
admet-24	265	6	aggregation	aggregation	NOUN
admet-24	265	7	-	-	PUNCT
admet-24	265	8	solubility	solubility	NOUN
admet-24	265	9	equations	equation	NOUN
admet-24	265	10	may	may	AUX
admet-24	265	11	be	be	AUX
admet-24	265	12	found	find	VERB
admet-24	265	13	in	in	ADP
admet-24	265	14	the	the	DET
admet-24	265	15	literature	literature	NOUN
admet-24	265	16	[	[	X
admet-24	265	17	19	19	NUM
admet-24	265	18	]	]	PUNCT
admet-24	265	19	.	.	PUNCT
admet-24	266	1	b	b	X
admet-24	266	2	)	)	PUNCT
admet-24	266	3	automatic	automatic	ADJ
admet-24	266	4	ionic	ionic	ADJ
admet-24	266	5	strength	strength	NOUN
admet-24	266	6	compensation	compensation	NOUN
admet-24	266	7	generally	generally	ADV
admet-24	266	8	,	,	PUNCT
admet-24	266	9	the	the	DET
admet-24	266	10	ionic	ionic	ADJ
admet-24	266	11	strength	strength	NOUN
admet-24	266	12	,	,	PUNCT
admet-24	266	13	i	i	PRON
admet-24	266	14	,	,	PUNCT
admet-24	266	15	changes	change	NOUN
admet-24	266	16	in	in	ADP
admet-24	266	17	the	the	DET
admet-24	266	18	course	course	NOUN
admet-24	266	19	of	of	ADP
admet-24	266	20	an	an	DET
admet-24	266	21	acid	acid	NOUN
admet-24	266	22	-	-	PUNCT
admet-24	266	23	base	base	NOUN
admet-24	266	24	titration	titration	NOUN
admet-24	266	25	due	due	ADP
admet-24	266	26	to	to	ADP
admet-24	266	27	ionizations	ionization	NOUN
admet-24	266	28	,	,	PUNCT
admet-24	266	29	additions	addition	NOUN
admet-24	266	30	of	of	ADP
admet-24	266	31	titrant	titrant	NOUN
admet-24	266	32	,	,	PUNCT
admet-24	266	33	and	and	CCONJ
admet-24	266	34	dilution	dilution	NOUN
admet-24	266	35	of	of	ADP
admet-24	266	36	concentrations	concentration	NOUN
admet-24	266	37	.	.	PUNCT
admet-24	267	1	this	this	DET
admet-24	267	2	change	change	NOUN
admet-24	267	3	affects	affect	VERB
admet-24	267	4	acid	acid	NOUN
admet-24	267	5	-	-	PUNCT
admet-24	267	6	base	base	NOUN
admet-24	267	7	equilibrium	equilibrium	NOUN
admet-24	267	8	constants	constant	NOUN
admet-24	267	9	.	.	PUNCT
admet-24	268	1	in	in	ADP
admet-24	268	2	solubility	solubility	NOUN
admet-24	268	3	experiments	experiment	NOUN
admet-24	268	4	designed	design	VERB
admet-24	268	5	to	to	PART
admet-24	268	6	determine	determine	VERB
admet-24	268	7	salt	salt	NOUN
admet-24	268	8	solubility	solubility	NOUN
admet-24	268	9	products	product	NOUN
admet-24	268	10	,	,	PUNCT
admet-24	268	11	ksp	ksp	PROPN
admet-24	268	12	,	,	PUNCT
admet-24	268	13	the	the	DET
admet-24	268	14	ionic	ionic	ADJ
admet-24	268	15	strength	strength	NOUN
admet-24	268	16	can	can	AUX
admet-24	268	17	vary	vary	VERB
admet-24	268	18	substantially	substantially	ADV
admet-24	268	19	during	during	ADP
admet-24	268	20	a	a	DET
admet-24	268	21	titration	titration	NOUN
admet-24	268	22	,	,	PUNCT
admet-24	268	23	and	and	CCONJ
admet-24	268	24	sometimes	sometimes	ADV
admet-24	268	25	reaches	reach	VERB
admet-24	268	26	values	value	NOUN
admet-24	268	27	as	as	ADV
admet-24	268	28	high	high	ADJ
admet-24	268	29	as	as	ADP
admet-24	268	30	1	1	NUM
admet-24	268	31	m	m	NOUN
admet-24	268	32	,	,	PUNCT
admet-24	268	33	or	or	CCONJ
admet-24	268	34	even	even	ADV
admet-24	268	35	higher	high	ADJ
admet-24	268	36	.	.	PUNCT
admet-24	269	1	in	in	ADP
admet-24	269	2	contrast	contrast	NOUN
admet-24	269	3	,	,	PUNCT
admet-24	269	4	ionization	ionization	NOUN
admet-24	269	5	constants	constant	NOUN
admet-24	269	6	,	,	PUNCT
admet-24	269	7	pka	pka	PROPN
admet-24	269	8	,	,	PUNCT
admet-24	269	9	are	be	AUX
admet-24	269	10	determined	determine	VERB
admet-24	269	11	at	at	ADP
admet-24	269	12	a	a	DET
admet-24	269	13	nearly	nearly	ADV
admet-24	269	14	constant	constant	ADJ
admet-24	269	15	i	i	NOUN
admet-24	269	16	=	=	PUNCT
admet-24	269	17	0.15	0.15	NUM
admet-24	269	18	m	m	PROPN
admet-24	269	19	,	,	PUNCT
admet-24	269	20	under	under	ADP
admet-24	269	21	conditions	condition	NOUN
admet-24	269	22	where	where	SCONJ
admet-24	269	23	low	low	ADJ
admet-24	269	24	sample	sample	NOUN
admet-24	269	25	concentrations	concentration	NOUN
admet-24	269	26	(	(	PUNCT
admet-24	269	27	e.g.	e.g.	ADV
admet-24	269	28	,	,	PUNCT
admet-24	269	29	10	10	NUM
admet-24	269	30	-	-	SYM
admet-24	269	31	3	3	NUM
admet-24	269	32	to	to	PART
admet-24	269	33	10	10	NUM
admet-24	269	34	-	-	SYM
admet-24	269	35	6	6	NUM
admet-24	269	36	m	m	NOUN
admet-24	269	37	)	)	PUNCT
admet-24	269	38	are	be	AUX
admet-24	269	39	“	"	PUNCT
admet-24	269	40	swamped	swamp	VERB
admet-24	269	41	”	"	PUNCT
admet-24	269	42	by	by	ADP
admet-24	269	43	the	the	DET
admet-24	269	44	added	add	VERB
admet-24	269	45	inert	inert	ADJ
admet-24	269	46	salt	salt	NOUN
admet-24	269	47	(	(	PUNCT
admet-24	269	48	e.g.	e.g.	ADV
admet-24	269	49	,	,	PUNCT
admet-24	269	50	0.15	0.15	NUM
admet-24	269	51	m	m	NOUN
admet-24	269	52	nacl	nacl	NOUN
admet-24	269	53	or	or	CCONJ
admet-24	269	54	kcl	kcl	NOUN
admet-24	269	55	)	)	PUNCT
admet-24	269	56	.	.	PUNCT
admet-24	270	1	the	the	DET
admet-24	270	2	independently	independently	ADV
admet-24	270	3	-	-	PUNCT
admet-24	270	4	determined	determine	VERB
admet-24	270	5	pka	pka	PROPN
admet-24	270	6	constants	constant	NOUN
admet-24	270	7	are	be	AUX
admet-24	270	8	critical	critical	ADJ
admet-24	270	9	to	to	ADP
admet-24	270	10	the	the	DET
admet-24	270	11	analysis	analysis	NOUN
admet-24	270	12	of	of	ADP
admet-24	270	13	solubility	solubility	NOUN
admet-24	270	14	data	datum	NOUN
admet-24	270	15	,	,	PUNCT
admet-24	270	16	and	and	CCONJ
admet-24	270	17	thus	thus	ADV
admet-24	270	18	the	the	DET
admet-24	270	19	above	above	ADJ
admet-24	270	20	large	large	ADJ
admet-24	270	21	differences	difference	NOUN
admet-24	270	22	in	in	ADP
admet-24	270	23	ionic	ionic	ADJ
admet-24	270	24	strength	strength	NOUN
admet-24	270	25	need	need	VERB
admet-24	270	26	to	to	PART
admet-24	270	27	be	be	AUX
admet-24	270	28	factored	factor	VERB
admet-24	270	29	in	in	ADP
admet-24	270	30	,	,	PUNCT
admet-24	270	31	as	as	SCONJ
admet-24	270	32	described	describe	VERB
admet-24	270	33	here	here	ADV
admet-24	270	34	.	.	PUNCT
admet-24	271	1	it	it	PRON
admet-24	271	2	is	be	AUX
admet-24	271	3	a	a	DET
admet-24	271	4	reasonable	reasonable	ADJ
admet-24	271	5	practice	practice	NOUN
admet-24	271	6	to	to	PART
admet-24	271	7	designate	designate	VERB
admet-24	271	8	0.15	0.15	NUM
admet-24	271	9	m	m	NOUN
admet-24	271	10	as	as	SCONJ
admet-24	271	11	the	the	DET
admet-24	271	12	“	"	PUNCT
admet-24	271	13	reference	reference	NOUN
admet-24	271	14	”	"	PUNCT
admet-24	271	15	ionic	ionic	ADJ
admet-24	271	16	strength	strength	NOUN
admet-24	271	17	,	,	PUNCT
admet-24	271	18	iref	iref	NOUN
admet-24	271	19	,	,	PUNCT
admet-24	271	20	(	(	PUNCT
admet-24	271	21	“	"	PUNCT
admet-24	271	22	physiological	physiological	ADJ
admet-24	271	23	”	"	PUNCT
admet-24	271	24	level	level	NOUN
admet-24	271	25	)	)	PUNCT
admet-24	271	26	to	to	PART
admet-24	271	27	which	which	PRON
admet-24	271	28	all	all	DET
admet-24	271	29	equilibrium	equilibrium	NOUN
admet-24	271	30	constants	constant	NOUN
admet-24	271	31	are	be	AUX
admet-24	271	32	scaled	scale	VERB
admet-24	271	33	in	in	ADP
admet-24	271	34	the	the	DET
admet-24	271	35	solubility	solubility	NOUN
admet-24	271	36	assay	assay	VERB
admet-24	271	37	.	.	PUNCT
admet-24	272	1	in	in	ADP
admet-24	272	2	the	the	DET
admet-24	272	3	older	old	ADJ
admet-24	272	4	literature	literature	NOUN
admet-24	272	5	,	,	PUNCT
admet-24	272	6	the	the	DET
admet-24	272	7	reference	reference	NOUN
admet-24	272	8	state	state	NOUN
admet-24	272	9	was	be	AUX
admet-24	272	10	often	often	ADV
admet-24	272	11	chosen	choose	VERB
admet-24	272	12	as	as	ADP
admet-24	272	13	zero	zero	NUM
admet-24	272	14	,	,	PUNCT
admet-24	272	15	but	but	CCONJ
admet-24	272	16	in	in	ADP
admet-24	272	17	current	current	ADJ
admet-24	272	18	pharmaceutical	pharmaceutical	ADJ
admet-24	272	19	applications	application	NOUN
admet-24	272	20	,	,	PUNCT
admet-24	272	21	0.15	0.15	NUM
admet-24	272	22	m	m	NOUN
admet-24	272	23	is	be	AUX
admet-24	272	24	usually	usually	ADV
admet-24	272	25	chosen	choose	VERB
admet-24	272	26	,	,	PUNCT
admet-24	272	27	with	with	ADP
admet-24	272	28	no	no	DET
admet-24	272	29	loss	loss	NOUN
admet-24	272	30	of	of	ADP
admet-24	272	31	thermodynamic	thermodynamic	ADJ
admet-24	272	32	rigor	rigor	NOUN
admet-24	273	1	[	[	X
admet-24	273	2	19	19	NUM
admet-24	273	3	]	]	PUNCT
admet-24	273	4	.	.	PUNCT
admet-24	274	1	since	since	SCONJ
admet-24	274	2	the	the	DET
admet-24	274	3	ionic	ionic	ADJ
admet-24	274	4	strength	strength	NOUN
admet-24	274	5	at	at	ADP
admet-24	274	6	any	any	DET
admet-24	274	7	given	give	VERB
admet-24	274	8	ph	ph	ADJ
admet-24	274	9	point	point	NOUN
admet-24	274	10	in	in	ADP
admet-24	274	11	a	a	DET
admet-24	274	12	titration	titration	NOUN
admet-24	274	13	is	be	AUX
admet-24	274	14	likely	likely	ADV
admet-24	274	15	different	different	ADJ
admet-24	274	16	from	from	ADP
admet-24	274	17	iref	iref	NOUN
admet-24	274	18	,	,	PUNCT
admet-24	274	19	all	all	DET
admet-24	274	20	ionization	ionization	NOUN
admet-24	274	21	constants	constant	NOUN
admet-24	274	22	need	need	VERB
admet-24	274	23	to	to	PART
admet-24	274	24	be	be	AUX
admet-24	274	25	locally	locally	ADV
admet-24	274	26	transformed	transform	VERB
admet-24	274	27	(	(	PUNCT
admet-24	274	28	from	from	ADP
admet-24	274	29	reference	reference	NOUN
admet-24	274	30	iref	iref	NOUN
admet-24	274	31	to	to	ADP
admet-24	274	32	local	local	ADJ
admet-24	274	33	i	i	PROPN
admet-24	274	34	)	)	PUNCT
admet-24	274	35	for	for	ADP
admet-24	274	36	the	the	DET
admet-24	274	37	calculation	calculation	NOUN
admet-24	274	38	of	of	ADP
admet-24	274	39	local	local	ADJ
admet-24	274	40	point	point	NOUN
admet-24	274	41	concentrations	concentration	NOUN
admet-24	274	42	.	.	PUNCT
admet-24	275	1	the	the	DET
admet-24	275	2	procedure	procedure	NOUN
admet-24	275	3	below	below	ADV
admet-24	275	4	describes	describe	VERB
admet-24	275	5	such	such	DET
admet-24	275	6	an	an	DET
admet-24	275	7	adjustment	adjustment	NOUN
admet-24	275	8	of	of	ADP
admet-24	275	9	activity	activity	NOUN
admet-24	275	10	coefficients	coefficient	NOUN
admet-24	275	11	.	.	PUNCT
admet-24	276	1	consider	consider	VERB
admet-24	276	2	a	a	DET
admet-24	276	3	three	three	NUM
admet-24	276	4	-	-	PUNCT
admet-24	276	5	reactant	reactant	NOUN
admet-24	276	6	system	system	NOUN
admet-24	276	7	,	,	PUNCT
admet-24	276	8	based	base	VERB
admet-24	276	9	on	on	ADP
admet-24	276	10	reactants	reactant	NOUN
admet-24	276	11	x	x	X
admet-24	276	12	,	,	PUNCT
admet-24	276	13	y	y	PROPN
admet-24	276	14	and	and	CCONJ
admet-24	276	15	h	h	PROPN
admet-24	276	16	(	(	PUNCT
admet-24	276	17	proton	proton	NOUN
admet-24	276	18	)	)	PUNCT
admet-24	276	19	,	,	PUNCT
admet-24	276	20	whose	whose	DET
admet-24	276	21	charges	charge	NOUN
admet-24	276	22	are	be	AUX
admet-24	276	23	qx	qx	PROPN
admet-24	276	24	,	,	PUNCT
admet-24	276	25	qy	qy	PROPN
admet-24	276	26	,	,	PUNCT
admet-24	276	27	and	and	CCONJ
admet-24	276	28	+1	+1	PROPN
admet-24	276	29	.	.	PUNCT
admet-24	277	1	the	the	DET
admet-24	277	2	concentration	concentration	NOUN
admet-24	277	3	of	of	ADP
admet-24	277	4	the	the	DET
admet-24	277	5	jth	jth	PROPN
admet-24	277	6	particular	particular	ADJ
admet-24	277	7	species	species	PROPN
admet-24	277	8	,	,	PUNCT
admet-24	277	9	cj	cj	X
admet-24	277	10	,	,	PUNCT
admet-24	277	11	is	be	AUX
admet-24	277	12	defined	define	VERB
admet-24	277	13	in	in	ADP
admet-24	277	14	terms	term	NOUN
admet-24	277	15	of	of	ADP
admet-24	277	16	these	these	DET
admet-24	277	17	reactants	reactant	NOUN
admet-24	277	18	cj	cj	NOUN
admet-24	277	19	=	=	PUNCT
admet-24	278	1	[	[	X
admet-24	278	2	xqx]exj	xqx]exj	X
admet-24	278	3	[	[	X
admet-24	278	4	yqy]eyj	yqy]eyj	X
admet-24	278	5	[	[	X
admet-24	278	6	h+]ehj	h+]ehj	NOUN
admet-24	278	7	βj	βj	X
admet-24	278	8	(	(	PUNCT
admet-24	278	9	b1	b1	PROPN
admet-24	278	10	)	)	PUNCT
admet-24	278	11	associated	associate	VERB
admet-24	278	12	with	with	ADP
admet-24	278	13	the	the	DET
admet-24	278	14	general	general	ADJ
admet-24	278	15	equilibrium	equilibrium	NOUN
admet-24	278	16	expression	expression	NOUN
admet-24	278	17	exj	exj	NOUN
admet-24	278	18	x	x	PUNCT
admet-24	279	1	+	+	CCONJ
admet-24	279	2	eyj	eyj	PROPN
admet-24	279	3	y	y	PROPN
admet-24	279	4	+	+	PROPN
admet-24	279	5	ehj	ehj	PROPN
admet-24	279	6	h	h	PROPN
admet-24	279	7			PROPN
admet-24	279	8	xexjyeyjhehj	xexjyeyjhehj	PROPN
admet-24	279	9	(	(	PUNCT
admet-24	279	10	b2	b2	PROPN
admet-24	279	11	)	)	PUNCT
admet-24	279	12	where	where	SCONJ
admet-24	279	13	βj	βj	PRON
admet-24	279	14	is	be	AUX
admet-24	279	15	the	the	DET
admet-24	279	16	cumulative	cumulative	ADJ
admet-24	279	17	formation	formation	NOUN
admet-24	279	18	constant	constant	ADJ
admet-24	279	19	[	[	X
admet-24	279	20	19	19	NUM
admet-24	279	21	]	]	PUNCT
admet-24	279	22	,	,	PUNCT
admet-24	279	23	and	and	CCONJ
admet-24	279	24	exj	exj	NOUN
admet-24	279	25	,	,	PUNCT
admet-24	279	26	eyj	eyj	NOUN
admet-24	279	27	,	,	PUNCT
admet-24	279	28	and	and	CCONJ
admet-24	279	29	ehj	ehj	NOUN
admet-24	279	30	are	be	AUX
admet-24	279	31	the	the	DET
admet-24	279	32	x	x	PROPN
admet-24	279	33	,	,	PUNCT
admet-24	279	34	y	y	PROPN
admet-24	279	35	,	,	PUNCT
admet-24	279	36	and	and	CCONJ
admet-24	279	37	h	h	NOUN
admet-24	279	38	stoichiometric	stoichiometric	ADJ
admet-24	279	39	coefficients	coefficient	NOUN
admet-24	279	40	,	,	PUNCT
admet-24	279	41	respectively	respectively	ADV
admet-24	279	42	,	,	PUNCT
admet-24	279	43	of	of	ADP
admet-24	279	44	the	the	DET
admet-24	279	45	jth	jth	PROPN
admet-24	279	46	species	species	PROPN
admet-24	279	47	.	.	PUNCT
admet-24	280	1	at	at	ADP
admet-24	280	2	each	each	DET
admet-24	280	3	ph	ph	ADJ
admet-24	280	4	point	point	NOUN
admet-24	280	5	in	in	ADP
admet-24	280	6	a	a	DET
admet-24	280	7	solubility	solubility	NOUN
admet-24	280	8	assay	assay	VERB
admet-24	280	9	,	,	PUNCT
admet-24	280	10	i	i	PRON
admet-24	280	11	is	be	AUX
admet-24	280	12	calculated	calculate	VERB
admet-24	280	13	precisely	precisely	ADV
admet-24	280	14	,	,	PUNCT
admet-24	280	15	according	accord	VERB
admet-24	280	16	to	to	ADP
admet-24	280	17	the	the	DET
admet-24	280	18	general	general	ADJ
admet-24	280	19	formula	formula	NOUN
admet-24	280	20	[	[	X
admet-24	280	21	32	32	NUM
admet-24	280	22	]	]	PUNCT
admet-24	280	23	:	:	PUNCT
admet-24	281	1	i	i	PRON
admet-24	281	2	=	=	PUNCT
admet-24	282	1	[	[	X
admet-24	282	2	nacl	nacl	NOUN
admet-24	282	3	]	]	X
admet-24	282	4	+	+	CCONJ
admet-24	283	1	[	[	X
admet-24	283	2	naoh	naoh	NOUN
admet-24	283	3	]	]	X
admet-24	283	4	+	+	CCONJ
admet-24	283	5	[	[	X
admet-24	283	6	h+	h+	X
admet-24	283	7	]	]	X
admet-24	283	8	+	+	NUM
admet-24	283	9	½{qx(1+qx	½{qx(1+qx	NOUN
admet-24	283	10	)	)	PUNCT
admet-24	283	11	x	x	PUNCT
admet-24	284	1	+	+	NUM
admet-24	284	2	qy(1+qx	qy(1+qx	X
admet-24	284	3	)	)	PUNCT
admet-24	284	4	y	y	PROPN
admet-24	284	5	+	+	CCONJ
admet-24	284	6	σ	σ	NUM
admet-24	284	7	qj(1+qj	qj(1+qj	NOUN
admet-24	284	8	)	)	PUNCT
admet-24	284	9	cj	cj	NOUN
admet-24	284	10	}	}	PUNCT
admet-24	285	1	+	+	NUM
admet-24	285	2	½	½	NOUN
admet-24	285	3	{	{	PUNCT
admet-24	285	4	│	│	NOUN
admet-24	285	5	qx	qx	PROPN
admet-24	285	6	+	+	NUM
admet-24	285	7	nx	nx	PROPN
admet-24	285	8	│	│	NUM
admet-24	285	9	qx	qx	PROPN
admet-24	285	10	–	–	PUNCT
admet-24	285	11	nx	nx	NOUN
admet-24	285	12	}	}	PUNCT
admet-24	285	13	x	x	PROPN
admet-24	286	1	+	+	NUM
admet-24	286	2	½	½	NOUN
admet-24	286	3	{	{	PUNCT
admet-24	286	4	│	│	NOUN
admet-24	286	5	qy	qy	NOUN
admet-24	286	6	+	+	PROPN
admet-24	286	7	ny	ny	PROPN
admet-24	286	8	│	│	PROPN
admet-24	286	9	qy	qy	PROPN
admet-24	286	10	–	–	PUNCT
admet-24	286	11	ny	ny	PROPN
admet-24	286	12	)	)	PUNCT
admet-24	286	13	}	}	PUNCT
admet-24	286	14	y	y	PROPN
admet-24	286	15	(	(	PUNCT
admet-24	286	16	b3	b3	PROPN
admet-24	286	17	)	)	PUNCT
admet-24	286	18	admet	admet	PROPN
admet-24	286	19	&	&	CCONJ
admet-24	286	20	dmpk	dmpk	PROPN
admet-24	286	21	1(4	1(4	NUM
admet-24	286	22	)	)	PUNCT
admet-24	286	23	(	(	PUNCT
admet-24	286	24	2013	2013	NUM
admet-24	286	25	)	)	PUNCT
admet-24	286	26	48	48	NUM
admet-24	286	27	-	-	SYM
admet-24	286	28	62	62	NUM
admet-24	286	29	novel	novel	NOUN
admet-24	286	30	method	method	NOUN
admet-24	286	31	of	of	ADP
admet-24	286	32	salt	salt	NOUN
admet-24	286	33	solubility	solubility	NOUN
admet-24	286	34	analysis	analysis	NOUN
admet-24	286	35	doi	doi	NOUN
admet-24	286	36	:	:	PUNCT
admet-24	286	37	10.5599	10.5599	NUM
admet-24	286	38	/	/	SYM
admet-24	286	39	admet.1.4.24	admet.1.4.24	PROPN
admet-24	286	40	61	61	NUM
admet-24	286	41	the	the	DET
admet-24	286	42	last	last	ADJ
admet-24	286	43	two	two	NUM
admet-24	286	44	terms	term	NOUN
admet-24	286	45	in	in	ADP
admet-24	286	46	braces	brace	NOUN
admet-24	286	47	in	in	ADP
admet-24	286	48	eq	eq	ADP
admet-24	286	49	.	.	PUNCT
admet-24	286	50	b3	b3	PROPN
admet-24	286	51	take	take	VERB
admet-24	286	52	into	into	ADP
admet-24	286	53	account	account	NOUN
admet-24	286	54	any	any	DET
admet-24	286	55	nx	nx	NOUN
admet-24	286	56	or	or	CCONJ
admet-24	286	57	ny	ny	NOUN
admet-24	286	58	number	number	NOUN
admet-24	286	59	of	of	ADP
admet-24	286	60	counter	counter	ADJ
admet-24	286	61	ions	ion	NOUN
admet-24	286	62	introduced	introduce	VERB
admet-24	286	63	to	to	ADP
admet-24	286	64	the	the	DET
admet-24	286	65	solution	solution	NOUN
admet-24	286	66	by	by	ADP
admet-24	286	67	drug	drug	NOUN
admet-24	286	68	substances	substance	NOUN
admet-24	286	69	in	in	ADP
admet-24	286	70	salt	salt	NOUN
admet-24	286	71	form	form	NOUN
admet-24	286	72	(	(	PUNCT
admet-24	286	73	per	per	ADP
admet-24	286	74	xor	xor	PROPN
admet-24	286	75	y	y	PROPN
admet-24	286	76	-	-	PUNCT
admet-24	286	77	compound	compound	NOUN
admet-24	286	78	,	,	PUNCT
admet-24	286	79	respectively	respectively	ADV
admet-24	286	80	)	)	PUNCT
admet-24	286	81	.	.	PUNCT
admet-24	287	1	the	the	DET
admet-24	287	2	reference	reference	NOUN
admet-24	287	3	set	set	NOUN
admet-24	287	4	of	of	ADP
admet-24	287	5	β(iref	β(iref	NOUN
admet-24	287	6	)	)	PUNCT
admet-24	287	7	formation	formation	NOUN
admet-24	287	8	constants	constant	NOUN
admet-24	287	9	are	be	AUX
admet-24	287	10	locally	locally	ADV
admet-24	287	11	transformed	transform	VERB
admet-24	287	12	to	to	ADP
admet-24	287	13	the	the	DET
admet-24	287	14	set	set	NOUN
admet-24	287	15	β(i	β(i	PRON
admet-24	287	16	)	)	PUNCT
admet-24	287	17	according	accord	VERB
admet-24	287	18	to	to	ADP
admet-24	287	19	the	the	DET
admet-24	287	20	general	general	ADJ
admet-24	287	21	expression	expression	NOUN
admet-24	287	22	:	:	PUNCT
admet-24	287	23			ADJ
admet-24	287	24			PROPN
admet-24	287	25			PROPN
admet-24	287	26			X
admet-24	287	27			NOUN
admet-24	287	28			NOUN
admet-24	287	29			VERB
admet-24	287	30			PROPN
admet-24	287	31			NOUN
admet-24	287	32			PROPN
admet-24	287	33			PROPN
admet-24	287	34			PROPN
admet-24	287	35			X
admet-24	287	36			NOUN
admet-24	287	37			X
admet-24	287	38			VERB
admet-24	287	39			PROPN
admet-24	287	40			ADJ
admet-24	287	41			PROPN
admet-24	287	42			PROPN
admet-24	287	43			PROPN
admet-24	287	44			X
admet-24	287	45			NOUN
admet-24	287	46			X
admet-24	287	47			VERB
admet-24	287	48			PROPN
admet-24	287	49			ADJ
admet-24	287	50			PROPN
admet-24	287	51			PROPN
admet-24	287	52			PROPN
admet-24	287	53			X
admet-24	287	54			NOUN
admet-24	287	55			X
admet-24	287	56			VERB
admet-24	287	57			PROPN
admet-24	287	58			ADJ
admet-24	287	59	)	)	PUNCT
admet-24	287	60	(	(	PUNCT
admet-24	287	61	)	)	PUNCT
admet-24	287	62	(	(	PUNCT
admet-24	287	63	log	log	NOUN
admet-24	287	64	)	)	PUNCT
admet-24	287	65	(	(	PUNCT
admet-24	287	66	)	)	PUNCT
admet-24	287	67	(	(	PUNCT
admet-24	287	68	log	log	NOUN
admet-24	287	69	)	)	PUNCT
admet-24	287	70	(	(	PUNCT
admet-24	287	71	)	)	PUNCT
admet-24	287	72	(	(	PUNCT
admet-24	287	73	log	log	NOUN
admet-24	287	74	)	)	PUNCT
admet-24	287	75	(	(	PUNCT
admet-24	287	76	)	)	PUNCT
admet-24	287	77	(	(	PUNCT
admet-24	287	78	log)(log)(log	log)(log)(log	PROPN
admet-24	287	79	refj	refj	PROPN
admet-24	287	80	j	j	PROPN
admet-24	287	81	refh	refh	PROPN
admet-24	287	82	h	h	PROPN
admet-24	287	83	hj	hj	AUX
admet-24	287	84	refy	refy	PROPN
admet-24	287	85	y	y	PROPN
admet-24	287	86	yj	yj	PROPN
admet-24	287	87	refx	refx	PROPN
admet-24	287	88	x	x	PROPN
admet-24	287	89	xjrefjj	xjrefjj	NOUN
admet-24	287	90	if	if	SCONJ
admet-24	287	91	if	if	SCONJ
admet-24	287	92	if	if	SCONJ
admet-24	287	93	if	if	SCONJ
admet-24	287	94	e	e	NOUN
admet-24	287	95	if	if	SCONJ
admet-24	287	96	if	if	SCONJ
admet-24	287	97	e	e	NOUN
admet-24	287	98	if	if	SCONJ
admet-24	287	99	if	if	SCONJ
admet-24	287	100	eii	eii	PROPN
admet-24	287	101			NOUN
admet-24	287	102	(	(	PUNCT
admet-24	287	103	b4	b4	PROPN
admet-24	287	104	)	)	PUNCT
admet-24	287	105	where	where	SCONJ
admet-24	287	106	β(i	β(i	PRON
admet-24	287	107	)	)	PUNCT
admet-24	287	108	refers	refer	VERB
admet-24	287	109	to	to	ADP
admet-24	287	110	the	the	DET
admet-24	287	111	ionic	ionic	ADJ
admet-24	287	112	strength	strength	NOUN
admet-24	287	113	i	i	PRON
admet-24	287	114	,	,	PUNCT
admet-24	287	115	while	while	SCONJ
admet-24	287	116	β(iref	β(iref	PROPN
admet-24	287	117	)	)	PUNCT
admet-24	287	118	refers	refer	VERB
admet-24	287	119	to	to	AUX
admet-24	287	120	iref	iref	VERB
admet-24	287	121	.	.	PUNCT
admet-24	288	1	the	the	DET
admet-24	288	2	ionic	ionic	ADJ
admet-24	288	3	-	-	PUNCT
admet-24	288	4	strength	strength	NOUN
admet-24	288	5	-	-	PUNCT
admet-24	288	6	dependent	dependent	ADJ
admet-24	288	7	activity	activity	NOUN
admet-24	288	8	coefficients	coefficient	NOUN
admet-24	288	9	of	of	ADP
admet-24	288	10	x	x	NOUN
admet-24	288	11	,	,	PUNCT
admet-24	288	12	y	y	PROPN
admet-24	288	13	,	,	PUNCT
admet-24	288	14	h	h	NOUN
admet-24	288	15	,	,	PUNCT
admet-24	288	16	and	and	CCONJ
admet-24	288	17	j	j	PROPN
admet-24	288	18	th	th	X
admet-24	288	19	species	specie	NOUN
admet-24	288	20	(	(	PUNCT
admet-24	288	21	cf	cf	NOUN
admet-24	288	22	.	.	NOUN
admet-24	288	23	,	,	PUNCT
admet-24	288	24	eq	eq	NOUN
admet-24	288	25	.	.	PROPN
admet-24	288	26	b2	b2	PROPN
admet-24	288	27	)	)	PUNCT
admet-24	288	28	are	be	AUX
admet-24	288	29	denoted	denote	VERB
admet-24	288	30	fx	fx	PROPN
admet-24	288	31	,	,	PUNCT
admet-24	288	32	fy	fy	PROPN
admet-24	288	33	,	,	PUNCT
admet-24	288	34	fh	fh	PROPN
admet-24	288	35	,	,	PUNCT
admet-24	288	36	and	and	CCONJ
admet-24	288	37	fj	fj	INTJ
admet-24	288	38	,	,	PUNCT
admet-24	288	39	respectively	respectively	ADV
admet-24	288	40	.	.	PUNCT
admet-24	289	1	a	a	DET
admet-24	289	2	similar	similar	ADJ
admet-24	289	3	equation	equation	NOUN
admet-24	289	4	was	be	AUX
admet-24	289	5	introduced	introduce	VERB
admet-24	289	6	by	by	ADP
admet-24	289	7	avdeef	avdeef	NOUN
admet-24	289	8	[	[	X
admet-24	289	9	32	32	NUM
admet-24	289	10	]	]	PUNCT
admet-24	289	11	,	,	PUNCT
admet-24	289	12	based	base	VERB
admet-24	289	13	on	on	ADP
admet-24	289	14	the	the	DET
admet-24	289	15	davies	davy	NOUN
admet-24	289	16	-	-	PUNCT
admet-24	289	17	modified	modify	VERB
admet-24	289	18	debye	debye	ADJ
admet-24	289	19	-	-	PUNCT
admet-24	289	20	hückel	hückel	NOUN
admet-24	289	21	equation	equation	NOUN
admet-24	289	22	,	,	PUNCT
admet-24	289	23	which	which	PRON
admet-24	289	24	is	be	AUX
admet-24	289	25	reasonably	reasonably	ADV
admet-24	289	26	useful	useful	ADJ
admet-24	289	27	up	up	ADP
admet-24	289	28	to	to	ADP
admet-24	289	29	i	i	NOUN
admet-24	289	30	=	=	NOUN
admet-24	289	31	0.3	0.3	NUM
admet-24	289	32	m.	m.	NOUN
admet-24	289	33	since	since	SCONJ
admet-24	289	34	much	much	ADV
admet-24	289	35	higher	high	ADJ
admet-24	289	36	ionic	ionic	ADJ
admet-24	289	37	strengths	strength	NOUN
admet-24	289	38	are	be	AUX
admet-24	289	39	reached	reach	VERB
admet-24	289	40	in	in	ADP
admet-24	289	41	salt	salt	NOUN
admet-24	289	42	solubility	solubility	NOUN
admet-24	289	43	experiments	experiment	NOUN
admet-24	289	44	,	,	PUNCT
admet-24	290	1	eq	eq	NOUN
admet-24	290	2	.	.	PROPN
admet-24	290	3	b4	b4	NOUN
admet-24	290	4	in	in	ADP
admet-24	290	5	the	the	DET
admet-24	290	6	current	current	ADJ
admet-24	290	7	study	study	NOUN
admet-24	290	8	is	be	AUX
admet-24	290	9	cast	cast	VERB
admet-24	290	10	in	in	ADP
admet-24	290	11	an	an	DET
admet-24	290	12	expanded	expand	VERB
admet-24	290	13	activity	activity	NOUN
admet-24	290	14	coefficient	coefficient	NOUN
admet-24	290	15	equation	equation	NOUN
admet-24	290	16	based	base	VERB
admet-24	290	17	on	on	ADP
admet-24	290	18	the	the	DET
admet-24	290	19	hydration	hydration	NOUN
admet-24	290	20	theory	theory	NOUN
admet-24	290	21	proposed	propose	VERB
admet-24	290	22	by	by	ADP
admet-24	290	23	stokes	stoke	NOUN
admet-24	290	24	and	and	CCONJ
admet-24	290	25	robinson	robinson	PROPN
admet-24	291	1	[	[	X
admet-24	291	2	32,33	32,33	NUM
admet-24	291	3	]	]	PUNCT
admet-24	291	4	,	,	PUNCT
admet-24	291	5	further	far	ADV
admet-24	291	6	elaborated	elaborate	VERB
admet-24	291	7	by	by	ADP
admet-24	291	8	bates	bate	NOUN
admet-24	291	9	et	et	PROPN
admet-24	291	10	al	al	PROPN
admet-24	291	11	.	.	PUNCT
admet-24	292	1	[	[	X
admet-24	292	2	34	34	NUM
admet-24	292	3	]	]	PUNCT
admet-24	292	4	and	and	CCONJ
admet-24	292	5	robinson	robinson	PROPN
admet-24	292	6	and	and	CCONJ
admet-24	292	7	bates	bate	NOUN
admet-24	292	8	[	[	X
admet-24	292	9	35	35	NUM
admet-24	292	10	]	]	PUNCT
admet-24	292	11	to	to	PART
admet-24	292	12	include	include	VERB
admet-24	292	13	single	single	ADJ
admet-24	292	14	-	-	PUNCT
admet-24	292	15	ion	ion	NOUN
admet-24	292	16	activities	activity	NOUN
admet-24	292	17	,	,	PUNCT
admet-24	292	18	then	then	ADV
admet-24	292	19	slightly	slightly	ADV
admet-24	292	20	modified	modify	VERB
admet-24	292	21	by	by	ADP
admet-24	292	22	bockris	bockris	NOUN
admet-24	292	23	and	and	CCONJ
admet-24	292	24	reddy	reddy	PROPN
admet-24	293	1	[	[	X
admet-24	293	2	36	36	NUM
admet-24	293	3	]	]	PUNCT
admet-24	293	4	,	,	PUNCT
admet-24	293	5	and	and	CCONJ
admet-24	293	6	recently	recently	ADV
admet-24	293	7	applied	apply	VERB
admet-24	293	8	to	to	ADP
admet-24	293	9	solubility	solubility	NOUN
admet-24	293	10	data	datum	NOUN
admet-24	293	11	of	of	ADP
admet-24	293	12	a	a	DET
admet-24	293	13	drug	drug	NOUN
admet-24	293	14	-	-	PUNCT
admet-24	293	15	like	like	ADJ
admet-24	293	16	molecule	molecule	NOUN
admet-24	293	17	by	by	ADP
admet-24	293	18	wang	wang	PROPN
admet-24	293	19	et	et	PROPN
admet-24	293	20	al	al	PROPN
admet-24	293	21	.	.	PUNCT
admet-24	294	1	[	[	X
admet-24	294	2	7	7	NUM
admet-24	294	3	]	]	PUNCT
admet-24	294	4	:	:	PUNCT
admet-24	294	5			PROPN
admet-24	294	6			PROPN
admet-24	294	7			PROPN
admet-24	295	1			PROPN
admet-24	295	2			NOUN
admet-24	296	1			PROPN
admet-24	297	1			PROPN
admet-24	298	1			PROPN
admet-24	299	1			PROPN
admet-24	299	2			PROPN
admet-24	300	1			PROPN
admet-24	300	2			NOUN
admet-24	300	3			PUNCT
admet-24	300	4			ADV
admet-24	300	5			PROPN
admet-24	300	6			PUNCT
admet-24	300	7			X
admet-24	300	8			X
admet-24	300	9			X
admet-24	301	1	j	j	PROPN
admet-24	301	2	jj	jj	PROPN
admet-24	301	3	j	j	PROPN
admet-24	301	4	j	j	PROPN
admet-24	301	5	iii	iii	PROPN
admet-24	301	6	chc	chc	PROPN
admet-24	301	7	cc	cc	PROPN
admet-24	301	8	ah	ah	INTJ
admet-24	301	9	ib	ib	PROPN
admet-24	301	10	ia	ia	PROPN
admet-24	301	11	qif	qif	PROPN
admet-24	302	1	oh	oh	INTJ
admet-24	302	2	oh	oh	INTJ
admet-24	302	3	oh	oh	INTJ
admet-24	302	4	)	)	PUNCT
admet-24	302	5	1	1	NUM
admet-24	302	6	(	(	PUNCT
admet-24	302	7	loglog	loglog	NOUN
admet-24	302	8	å1	å1	PROPN
admet-24	302	9	)	)	PUNCT
admet-24	302	10	(	(	PUNCT
admet-24	302	11	log	log	NOUN
admet-24	302	12	2	2	NUM
admet-24	302	13	2	2	NUM
admet-24	302	14	2	2	NUM
admet-24	302	15	i	i	NOUN
admet-24	302	16	2	2	NUM
admet-24	302	17	(	(	PUNCT
admet-24	302	18	b5	b5	PROPN
admet-24	302	19	)	)	PUNCT
admet-24	302	20	the	the	DET
admet-24	302	21	first	first	ADJ
admet-24	302	22	term	term	NOUN
admet-24	302	23	on	on	ADP
admet-24	302	24	the	the	DET
admet-24	302	25	right	right	ADJ
admet-24	302	26	side	side	NOUN
admet-24	302	27	of	of	ADP
admet-24	302	28	eq	eq	PROPN
admet-24	302	29	.	.	PUNCT
admet-24	303	1	b5	b5	PROPN
admet-24	303	2	is	be	AUX
admet-24	303	3	the	the	DET
admet-24	303	4	debye	debye	ADJ
admet-24	303	5	-	-	PUNCT
admet-24	303	6	hückel	hückel	NOUN
admet-24	303	7	equation	equation	NOUN
admet-24	303	8	accounting	account	VERB
admet-24	303	9	for	for	ADP
admet-24	303	10	the	the	DET
admet-24	303	11	ion	ion	NOUN
admet-24	303	12	-	-	PUNCT
admet-24	303	13	ion	ion	NOUN
admet-24	303	14	electrostatic	electrostatic	ADJ
admet-24	303	15	interactions	interaction	NOUN
admet-24	303	16	;	;	PUNCT
admet-24	303	17	the	the	DET
admet-24	303	18	second	second	ADJ
admet-24	303	19	term	term	NOUN
admet-24	303	20	is	be	AUX
admet-24	303	21	related	relate	VERB
admet-24	303	22	to	to	ADP
admet-24	303	23	the	the	DET
admet-24	303	24	decrease	decrease	NOUN
admet-24	303	25	in	in	ADP
admet-24	303	26	the	the	DET
admet-24	303	27	activity	activity	NOUN
admet-24	303	28	of	of	ADP
admet-24	303	29	water	water	NOUN
admet-24	303	30	due	due	ADP
admet-24	303	31	to	to	ADP
admet-24	303	32	the	the	DET
admet-24	303	33	work	work	NOUN
admet-24	303	34	done	do	VERB
admet-24	303	35	in	in	ADP
admet-24	303	36	immobilizing	immobilize	VERB
admet-24	303	37	some	some	PRON
admet-24	303	38	of	of	ADP
admet-24	303	39	the	the	DET
admet-24	303	40	bulk	bulk	ADJ
admet-24	303	41	water	water	NOUN
admet-24	303	42	to	to	PART
admet-24	303	43	hydrate	hydrate	VERB
admet-24	303	44	ions	ion	NOUN
admet-24	303	45	;	;	PUNCT
admet-24	303	46	the	the	DET
admet-24	303	47	third	third	ADJ
admet-24	303	48	term	term	NOUN
admet-24	303	49	is	be	AUX
admet-24	303	50	related	relate	VERB
admet-24	303	51	to	to	ADP
admet-24	303	52	free	free	ADJ
admet-24	303	53	energy	energy	NOUN
admet-24	303	54	change	change	NOUN
admet-24	303	55	of	of	ADP
admet-24	303	56	the	the	DET
admet-24	303	57	ions	ion	NOUN
admet-24	303	58	,	,	PUNCT
admet-24	303	59	as	as	SCONJ
admet-24	303	60	their	their	PRON
admet-24	303	61	concentrations	concentration	NOUN
admet-24	303	62	effectively	effectively	ADV
admet-24	303	63	increase	increase	VERB
admet-24	303	64	when	when	SCONJ
admet-24	303	65	the	the	DET
admet-24	303	66	volume	volume	NOUN
admet-24	303	67	of	of	ADP
admet-24	303	68	bulk	bulk	ADJ
admet-24	303	69	water	water	NOUN
admet-24	303	70	decreases	decrease	VERB
admet-24	303	71	upon	upon	SCONJ
admet-24	303	72	hydration	hydration	NOUN
admet-24	303	73	of	of	ADP
admet-24	303	74	the	the	DET
admet-24	303	75	ions	ion	NOUN
admet-24	303	76	.	.	PUNCT
admet-24	304	1	the	the	DET
admet-24	304	2	parameters	parameter	NOUN
admet-24	304	3	at	at	ADP
admet-24	304	4	25c	25c	PROPN
admet-24	304	5	(	(	PUNCT
admet-24	304	6	molar	molar	ADJ
admet-24	304	7	scale	scale	NOUN
admet-24	304	8	):	):	PUNCT
admet-24	304	9	dielectric	dielectric	ADJ
admet-24	304	10	constant	constant	ADJ
admet-24	304	11	of	of	ADP
admet-24	304	12	water	water	NOUN
admet-24	304	13	,	,	PUNCT
admet-24	304	14	ε	ε	PROPN
admet-24	304	15	=	=	PUNCT
admet-24	304	16	78.3	78.3	NUM
admet-24	304	17	,	,	PUNCT
admet-24	304	18	76.8	76.8	NUM
admet-24	304	19	,	,	PUNCT
admet-24	304	20	67.3	67.3	NUM
admet-24	304	21	at	at	ADP
admet-24	304	22	i	i	PROPN
admet-24	304	23	=	=	NOUN
admet-24	304	24	0	0	NUM
admet-24	304	25	,	,	PUNCT
admet-24	304	26	0.15	0.15	NUM
admet-24	304	27	,	,	PUNCT
admet-24	304	28	and	and	CCONJ
admet-24	304	29	1	1	NUM
admet-24	304	30	m	m	NOUN
admet-24	304	31	(	(	PUNCT
admet-24	304	32	nacl	nacl	NOUN
admet-24	304	33	)	)	PUNCT
admet-24	304	34	,	,	PUNCT
admet-24	304	35	respectively	respectively	ADV
admet-24	304	36	[	[	X
admet-24	304	37	37	37	NUM
admet-24	304	38	]	]	PUNCT
admet-24	304	39	;	;	PUNCT
admet-24	304	40	the	the	DET
admet-24	304	41	debye	debye	ADJ
admet-24	304	42	-	-	PUNCT
admet-24	304	43	hückel	hückel	NOUN
admet-24	304	44	slope	slope	NOUN
admet-24	304	45	,	,	PUNCT
admet-24	304	46	a	a	DET
admet-24	304	47	=	=	SYM
admet-24	304	48	1.825x106	1.825x106	NUM
admet-24	304	49	(	(	PUNCT
admet-24	304	50	εt)-3/2	εt)-3/2	PROPN
admet-24	304	51	=	=	PUNCT
admet-24	304	52	0.512	0.512	NUM
admet-24	304	53	,	,	PUNCT
admet-24	304	54	0.528	0.528	NUM
admet-24	304	55	,	,	PUNCT
admet-24	304	56	0.642	0.642	NUM
admet-24	304	57	at	at	ADP
admet-24	304	58	i	i	PROPN
admet-24	304	59	=	=	NOUN
admet-24	304	60	0	0	NUM
admet-24	304	61	,	,	PUNCT
admet-24	304	62	0.15	0.15	NUM
admet-24	304	63	,	,	PUNCT
admet-24	304	64	and	and	CCONJ
admet-24	304	65	1	1	NUM
admet-24	304	66	m	m	NOUN
admet-24	304	67	,	,	PUNCT
admet-24	304	68	resp	resp	NOUN
admet-24	304	69	.	.	PUNCT
admet-24	304	70	;	;	PUNCT
admet-24	304	71	b	b	X
admet-24	304	72	=	=	SYM
admet-24	304	73	50.29	50.29	NUM
admet-24	304	74	(	(	PUNCT
admet-24	304	75	εt)-1/2	εt)-1/2	NOUN
admet-24	304	76	=	=	PUNCT
admet-24	304	77	0.329	0.329	NUM
admet-24	304	78	,	,	PUNCT
admet-24	304	79	0.333	0.333	NUM
admet-24	304	80	,	,	PUNCT
admet-24	304	81	0.355	0.355	NUM
admet-24	304	82	at	at	ADP
admet-24	304	83	i	i	PROPN
admet-24	304	84	=	=	NOUN
admet-24	304	85	0	0	NUM
admet-24	304	86	,	,	PUNCT
admet-24	304	87	0.15	0.15	NUM
admet-24	304	88	,	,	PUNCT
admet-24	304	89	1	1	NUM
admet-24	304	90	m	m	NOUN
admet-24	304	91	,	,	PUNCT
admet-24	304	92	resp	resp	NOUN
admet-24	304	93	.	.	PUNCT
admet-24	304	94	;	;	PUNCT
admet-24	304	95	t	t	PROPN
admet-24	304	96	is	be	AUX
admet-24	304	97	the	the	DET
admet-24	304	98	absolute	absolute	ADJ
admet-24	304	99	temperature	temperature	NOUN
admet-24	304	100	(	(	PUNCT
admet-24	304	101	k	k	NOUN
admet-24	304	102	)	)	PUNCT
admet-24	304	103	.	.	PUNCT
admet-24	305	1	the	the	DET
admet-24	305	2	two	two	NUM
admet-24	305	3	adjustable	adjustable	ADJ
admet-24	305	4	parameters	parameter	NOUN
admet-24	305	5	are	be	AUX
admet-24	305	6	åi	åi	NOUN
admet-24	305	7	,	,	PUNCT
admet-24	305	8	corresponding	correspond	VERB
admet-24	305	9	to	to	ADP
admet-24	305	10	the	the	DET
admet-24	305	11	mean	mean	ADJ
admet-24	305	12	diameter	diameter	NOUN
admet-24	305	13	of	of	ADP
admet-24	305	14	the	the	DET
admet-24	305	15	ith	ith	PROPN
admet-24	305	16	hydrated	hydrated	ADJ
admet-24	305	17	ion	ion	NOUN
admet-24	305	18	[	[	X
admet-24	305	19	38	38	NUM
admet-24	305	20	]	]	PUNCT
admet-24	305	21	,	,	PUNCT
admet-24	305	22	and	and	CCONJ
admet-24	305	23	hi	hi	INTJ
admet-24	305	24	,	,	PUNCT
admet-24	305	25	the	the	DET
admet-24	305	26	hydration	hydration	NOUN
admet-24	305	27	number	number	NOUN
admet-24	305	28	of	of	ADP
admet-24	305	29	the	the	DET
admet-24	305	30	ith	ith	PROPN
admet-24	305	31	ion	ion	NOUN
admet-24	305	32	[	[	X
admet-24	305	33	37	37	NUM
admet-24	305	34	]	]	PUNCT
admet-24	305	35	.	.	PUNCT
admet-24	306	1	the	the	DET
admet-24	306	2	activity	activity	NOUN
admet-24	306	3	of	of	ADP
admet-24	306	4	water	water	NOUN
admet-24	306	5	,	,	PUNCT
admet-24	306	6	ah2o	ah2o	VERB
admet-24	306	7	=	=	PUNCT
admet-24	306	8	1.000	1.000	NUM
admet-24	306	9	,	,	PUNCT
admet-24	306	10	0.995	0.995	NUM
admet-24	306	11	,	,	PUNCT
admet-24	306	12	0.967	0.967	NUM
admet-24	306	13	at	at	ADP
admet-24	306	14	i	i	PROPN
admet-24	306	15	=	=	NOUN
admet-24	306	16	0	0	NUM
admet-24	306	17	,	,	PUNCT
admet-24	306	18	0.15	0.15	NUM
admet-24	306	19	,	,	PUNCT
admet-24	306	20	1	1	NUM
admet-24	306	21	m	m	NOUN
admet-24	306	22	,	,	PUNCT
admet-24	306	23	respectively	respectively	ADV
admet-24	306	24	[	[	X
admet-24	306	25	36	36	NUM
admet-24	306	26	]	]	PUNCT
admet-24	306	27	.	.	PUNCT
admet-24	307	1	ch2o	ch2o	NOUN
admet-24	307	2	=	=	PUNCT
admet-24	307	3	55.51	55.51	NUM
admet-24	307	4	m	m	NOUN
admet-24	307	5	(	(	PUNCT
admet-24	307	6	concentration	concentration	NOUN
admet-24	307	7	of	of	ADP
admet-24	307	8	water	water	NOUN
admet-24	307	9	in	in	ADP
admet-24	307	10	pure	pure	ADJ
admet-24	307	11	solvent	solvent	NOUN
admet-24	307	12	form	form	NOUN
admet-24	307	13	,	,	PUNCT
admet-24	307	14	i	i	PRON
admet-24	307	15	=	=	NOUN
admet-24	307	16	0	0	NUM
admet-24	307	17	)	)	PUNCT
admet-24	307	18	.	.	PUNCT
admet-24	308	1	the	the	DET
admet-24	308	2	summation	summation	NOUN
admet-24	308	3	symbols	symbol	NOUN
admet-24	308	4	in	in	ADP
admet-24	308	5	eq	eq	ADP
admet-24	308	6	.	.	PUNCT
admet-24	309	1	b5	b5	PROPN
admet-24	309	2	are	be	AUX
admet-24	309	3	over	over	ADP
admet-24	309	4	all	all	DET
admet-24	309	5	charged	charge	VERB
admet-24	309	6	species	specie	NOUN
admet-24	309	7	(	(	PUNCT
admet-24	309	8	including	include	VERB
admet-24	309	9	the	the	DET
admet-24	309	10	reactants	reactant	NOUN
admet-24	309	11	)	)	PUNCT
admet-24	309	12	in	in	ADP
admet-24	309	13	the	the	DET
admet-24	309	14	system	system	NOUN
admet-24	309	15	.	.	PUNCT
admet-24	310	1	acknowledgements	acknowledgement	NOUN
admet-24	310	2	we	we	PRON
admet-24	310	3	thank	thank	VERB
admet-24	310	4	sándor	sándor	PROPN
admet-24	310	5	hosztafi	hosztafi	PROPN
admet-24	310	6	(	(	PUNCT
admet-24	310	7	semmelweis	semmelweis	PROPN
admet-24	310	8	university	university	PROPN
admet-24	310	9	,	,	PUNCT
admet-24	310	10	dept	dept	NOUN
admet-24	310	11	.	.	PROPN
admet-24	310	12	of	of	ADP
admet-24	310	13	pharmaceutical	pharmaceutical	ADJ
admet-24	310	14	chemistry	chemistry	NOUN
admet-24	310	15	)	)	PUNCT
admet-24	310	16	for	for	ADP
admet-24	310	17	the	the	DET
admet-24	310	18	synthesis	synthesis	NOUN
admet-24	310	19	of	of	ADP
admet-24	310	20	diprenoprhine	diprenoprhine	NOUN
admet-24	310	21	hydrochloride	hydrochloride	NOUN
admet-24	310	22	sample	sample	NOUN
admet-24	310	23	.	.	PUNCT
admet-24	311	1	we	we	PRON
admet-24	311	2	also	also	ADV
admet-24	311	3	thank	thank	VERB
admet-24	311	4	dénes	déne	NOUN
admet-24	311	5	janke	janke	VERB
admet-24	311	6	for	for	ADP
admet-24	311	7	the	the	DET
admet-24	311	8	xrpd	xrpd	PROPN
admet-24	311	9	measurements	measurement	NOUN
admet-24	311	10	.	.	PUNCT
admet-24	312	1	references	reference	NOUN
admet-24	312	2	[	[	X
admet-24	312	3	1	1	X
admet-24	312	4	]	]	PUNCT
admet-24	312	5	s.	s.	PROPN
admet-24	312	6	miyazaki	miyazaki	PROPN
admet-24	312	7	,	,	PUNCT
admet-24	312	8	h.	h.	PROPN
admet-24	312	9	inouie	inouie	PROPN
admet-24	312	10	,	,	PUNCT
admet-24	312	11	t.	t.	PROPN
admet-24	312	12	nadai	nadai	PROPN
admet-24	312	13	,	,	PUNCT
admet-24	312	14	t.	t.	NOUN
admet-24	312	15	arita	arita	PROPN
admet-24	312	16	,	,	PUNCT
admet-24	312	17	m.	m.	NOUN
admet-24	312	18	nakano	nakano	PROPN
admet-24	312	19	,	,	PUNCT
admet-24	312	20	chem	chem	NOUN
admet-24	312	21	.	.	PUNCT
admet-24	313	1	pharm	pharm	NOUN
admet-24	313	2	.	.	PUNCT
admet-24	314	1	bull	bull	NOUN
admet-24	314	2	.	.	PUNCT
admet-24	315	1	27	27	NUM
admet-24	315	2	(	(	PUNCT
admet-24	315	3	1979	1979	NUM
admet-24	315	4	)	)	PUNCT
admet-24	315	5	1441	1441	NUM
admet-24	315	6	-	-	SYM
admet-24	315	7	1447	1447	NUM
admet-24	315	8	.	.	PUNCT
admet-24	316	1	[	[	X
admet-24	316	2	2	2	X
admet-24	316	3	]	]	PUNCT
admet-24	316	4	s.	s.	PROPN
admet-24	316	5	miyazaki	miyazaki	PROPN
admet-24	316	6	,	,	PUNCT
admet-24	316	7	m.	m.	NOUN
admet-24	316	8	oshiba	oshiba	PROPN
admet-24	316	9	,	,	PUNCT
admet-24	316	10	t.	t.	PROPN
admet-24	316	11	nadai	nadai	PROPN
admet-24	316	12	,	,	PUNCT
admet-24	316	13	j.	j.	PROPN
admet-24	316	14	pharm	pharm	PROPN
admet-24	316	15	.	.	PUNCT
admet-24	317	1	sci	sci	PROPN
admet-24	317	2	.	.	PROPN
admet-24	318	1	70	70	NUM
admet-24	318	2	(	(	PUNCT
admet-24	318	3	1981	1981	NUM
admet-24	318	4	)	)	PUNCT
admet-24	318	5	594	594	NUM
admet-24	318	6	-	-	SYM
admet-24	318	7	596	596	NUM
admet-24	318	8	.	.	PUNCT
admet-24	319	1	[	[	X
admet-24	319	2	3	3	X
admet-24	319	3	]	]	X
admet-24	319	4	b.d	b.d	PROPN
admet-24	319	5	.	.	PROPN
admet-24	319	6	anderson	anderson	PROPN
admet-24	319	7	,	,	PUNCT
admet-24	319	8	r.a	r.a	PROPN
admet-24	319	9	.	.	PROPN
admet-24	319	10	conradi	conradi	PROPN
admet-24	319	11	,	,	PUNCT
admet-24	319	12	j.	j.	PROPN
admet-24	319	13	pharm	pharm	PROPN
admet-24	319	14	.	.	PUNCT
admet-24	320	1	sci	sci	PROPN
admet-24	320	2	.	.	PROPN
admet-24	321	1	74	74	NUM
admet-24	321	2	(	(	PUNCT
admet-24	321	3	1985	1985	NUM
admet-24	321	4	)	)	PUNCT
admet-24	321	5	815	815	NUM
admet-24	321	6	-	-	SYM
admet-24	321	7	820	820	NUM
admet-24	321	8	.	.	PUNCT
admet-24	322	1	[	[	X
admet-24	322	2	4	4	X
admet-24	322	3	]	]	X
admet-24	322	4	b.d	b.d	PROPN
admet-24	322	5	.	.	PROPN
admet-24	322	6	anderson	anderson	PROPN
admet-24	322	7	,	,	PUNCT
admet-24	322	8	k.p	k.p	PROPN
admet-24	322	9	.	.	PROPN
admet-24	322	10	flora	flora	PROPN
admet-24	322	11	,	,	PUNCT
admet-24	322	12	preparation	preparation	NOUN
admet-24	322	13	of	of	ADP
admet-24	322	14	water	water	NOUN
admet-24	322	15	-	-	PUNCT
admet-24	322	16	soluble	soluble	ADJ
admet-24	322	17	compounds	compound	NOUN
admet-24	322	18	through	through	ADP
admet-24	322	19	salt	salt	NOUN
admet-24	322	20	formation	formation	NOUN
admet-24	322	21	.	.	PUNCT
admet-24	323	1	in	in	ADP
admet-24	323	2	:	:	PUNCT
admet-24	323	3	c.g	c.g	PROPN
admet-24	323	4	.	.	PROPN
admet-24	323	5	wermuth	wermuth	PROPN
admet-24	323	6	(	(	PUNCT
admet-24	323	7	ed	ed	NOUN
admet-24	323	8	.	.	PUNCT
admet-24	323	9	)	)	PUNCT
admet-24	323	10	.	.	PUNCT
admet-24	324	1	the	the	DET
admet-24	324	2	practice	practice	NOUN
admet-24	324	3	of	of	ADP
admet-24	324	4	medicinal	medicinal	ADJ
admet-24	324	5	chemistry	chemistry	NOUN
admet-24	324	6	.	.	PUNCT
admet-24	325	1	academic	academic	ADJ
admet-24	325	2	press	press	PROPN
admet-24	325	3	,	,	PUNCT
admet-24	325	4	london	london	PROPN
admet-24	325	5	,	,	PUNCT
admet-24	325	6	1996	1996	NUM
admet-24	325	7	,	,	PUNCT
admet-24	325	8	pp	pp	ADV
admet-24	325	9	.	.	PUNCT
admet-24	326	1	739	739	NUM
admet-24	326	2	-	-	SYM
admet-24	326	3	754	754	NUM
admet-24	326	4	.	.	PUNCT
admet-24	327	1	[	[	X
admet-24	327	2	5	5	NUM
admet-24	327	3	]	]	X
admet-24	327	4	m.t	m.t	PROPN
admet-24	327	5	.	.	PROPN
admet-24	327	6	ledwidge	ledwidge	PROPN
admet-24	327	7	,	,	PUNCT
admet-24	327	8	o.i	o.i	PROPN
admet-24	327	9	.	.	PROPN
admet-24	327	10	corrigan	corrigan	PROPN
admet-24	327	11	,	,	PUNCT
admet-24	327	12	int	int	PROPN
admet-24	327	13	.	.	PUNCT
admet-24	328	1	j.	j.	PROPN
admet-24	328	2	pharm	pharm	PROPN
admet-24	328	3	.	.	PUNCT
admet-24	329	1	174	174	NUM
admet-24	329	2	(	(	PUNCT
admet-24	329	3	1998	1998	NUM
admet-24	329	4	)	)	PUNCT
admet-24	329	5	187	187	NUM
admet-24	329	6	-	-	SYM
admet-24	329	7	200	200	NUM
admet-24	329	8	.	.	PUNCT
admet-24	330	1	gergely	gergely	ADV
admet-24	330	2	völgyi	völgyi	VERB
admet-24	330	3	et	et	PROPN
admet-24	330	4	al	al	PROPN
admet-24	330	5	.	.	PROPN
admet-24	330	6	admet	admet	PROPN
admet-24	330	7	&	&	CCONJ
admet-24	330	8	dmpk	dmpk	PROPN
admet-24	330	9	1(4	1(4	NUM
admet-24	330	10	)	)	PUNCT
admet-24	330	11	(	(	PUNCT
admet-24	330	12	2013	2013	NUM
admet-24	330	13	)	)	PUNCT
admet-24	330	14	48	48	NUM
admet-24	330	15	-	-	SYM
admet-24	330	16	62	62	NUM
admet-24	330	17	62	62	NUM
admet-24	330	18	[	[	X
admet-24	330	19	6	6	NUM
admet-24	330	20	]	]	X
admet-24	330	21	a.t.m	a.t.m	X
admet-24	330	22	.	.	PUNCT
admet-24	331	1	serajuddin	serajuddin	PROPN
admet-24	331	2	,	,	PUNCT
admet-24	331	3	m.	m.	NOUN
admet-24	331	4	pudipeddi	pudipeddi	NOUN
admet-24	331	5	,	,	PUNCT
admet-24	331	6	salt	salt	NOUN
admet-24	331	7	selection	selection	NOUN
admet-24	331	8	strategies	strategy	NOUN
admet-24	331	9	,	,	PUNCT
admet-24	331	10	in	in	ADP
admet-24	331	11	:	:	PUNCT
admet-24	331	12	stahl	stahl	PROPN
admet-24	331	13	ph	ph	PROPN
admet-24	331	14	,	,	PUNCT
admet-24	331	15	wermuth	wermuth	NOUN
admet-24	331	16	cg	cg	NOUN
admet-24	331	17	(	(	PUNCT
admet-24	331	18	eds	ed	NOUN
admet-24	331	19	.	.	PUNCT
admet-24	331	20	)	)	PUNCT
admet-24	331	21	,	,	PUNCT
admet-24	331	22	handbook	handbook	NOUN
admet-24	331	23	of	of	ADP
admet-24	331	24	pharmaceutical	pharmaceutical	ADJ
admet-24	331	25	salts	salt	NOUN
admet-24	331	26	:	:	PUNCT
admet-24	331	27	properties	property	NOUN
admet-24	331	28	,	,	PUNCT
admet-24	331	29	selection	selection	NOUN
admet-24	331	30	,	,	PUNCT
admet-24	331	31	and	and	CCONJ
admet-24	331	32	use	use	NOUN
admet-24	331	33	,	,	PUNCT
admet-24	331	34	wiley	wiley	PROPN
admet-24	331	35	-	-	PUNCT
admet-24	331	36	vch	vch	PROPN
admet-24	331	37	,	,	PUNCT
admet-24	331	38	weinheim	weinheim	PROPN
admet-24	331	39	,	,	PUNCT
admet-24	331	40	2002	2002	NUM
admet-24	331	41	,	,	PUNCT
admet-24	331	42	pp	pp	ADJ
admet-24	331	43	.	.	PUNCT
admet-24	332	1	135	135	NUM
admet-24	332	2	-	-	SYM
admet-24	332	3	160	160	NUM
admet-24	332	4	.	.	PUNCT
admet-24	333	1	[	[	X
admet-24	333	2	7	7	X
admet-24	333	3	]	]	PUNCT
admet-24	333	4	z.	z.	PROPN
admet-24	333	5	wang	wang	PROPN
admet-24	333	6	,	,	PUNCT
admet-24	333	7	l.s	l.s	PROPN
admet-24	333	8	.	.	PROPN
admet-24	333	9	burrell	burrell	PROPN
admet-24	333	10	,	,	PUNCT
admet-24	333	11	w.j	w.j	PROPN
admet-24	333	12	.	.	PROPN
admet-24	333	13	lambert	lambert	PROPN
admet-24	333	14	,	,	PUNCT
admet-24	333	15	j.	j.	PROPN
admet-24	333	16	pharm	pharm	PROPN
admet-24	333	17	.	.	PUNCT
admet-24	334	1	sci	sci	PROPN
admet-24	334	2	.	.	PROPN
admet-24	335	1	91	91	NUM
admet-24	335	2	(	(	PUNCT
admet-24	335	3	2002	2002	NUM
admet-24	335	4	)	)	PUNCT
admet-24	335	5	1445	1445	NUM
admet-24	335	6	-	-	SYM
admet-24	335	7	1455	1455	NUM
admet-24	335	8	.	.	PUNCT
admet-24	336	1	[	[	X
admet-24	336	2	8	8	NUM
admet-24	336	3	]	]	X
admet-24	336	4	p.h	p.h	PROPN
admet-24	336	5	.	.	PROPN
admet-24	336	6	stahl	stahl	PROPN
admet-24	336	7	,	,	PUNCT
admet-24	336	8	salt	salt	NOUN
admet-24	336	9	selection	selection	NOUN
admet-24	336	10	,	,	PUNCT
admet-24	336	11	in	in	ADP
admet-24	336	12	:	:	PUNCT
admet-24	336	13	r.	r.	PROPN
admet-24	336	14	hilfiker	hilfiker	PROPN
admet-24	336	15	(	(	PUNCT
admet-24	336	16	ed	ed	NOUN
admet-24	336	17	.	.	PUNCT
admet-24	336	18	)	)	PUNCT
admet-24	336	19	,	,	PUNCT
admet-24	336	20	polymorphism	polymorphism	NOUN
admet-24	336	21	in	in	ADP
admet-24	336	22	pharmaceutical	pharmaceutical	NOUN
admet-24	336	23	industry	industry	NOUN
admet-24	336	24	,	,	PUNCT
admet-24	336	25	wiley	wiley	PROPN
admet-24	336	26	-	-	PUNCT
admet-24	336	27	vch	vch	PROPN
admet-24	336	28	,	,	PUNCT
admet-24	336	29	weinheim	weinheim	PROPN
admet-24	336	30	,	,	PUNCT
admet-24	336	31	2006	2006	NUM
admet-24	336	32	,	,	PUNCT
admet-24	336	33	pp	pp	ADV
admet-24	336	34	.	.	PUNCT
admet-24	337	1	309	309	NUM
admet-24	337	2	-	-	SYM
admet-24	337	3	322	322	NUM
admet-24	337	4	.	.	PUNCT
admet-24	338	1	[	[	X
admet-24	338	2	9	9	NUM
admet-24	338	3	]	]	PUNCT
admet-24	338	4	t.	t.	PROPN
admet-24	338	5	higuchi	higuchi	PROPN
admet-24	338	6	,	,	PUNCT
admet-24	338	7	m.	m.	NOUN
admet-24	338	8	gupta	gupta	PROPN
admet-24	338	9	,	,	PUNCT
admet-24	338	10	l.w	l.w	PROPN
admet-24	338	11	.	.	PROPN
admet-24	338	12	busse	busse	PROPN
admet-24	338	13	,	,	PUNCT
admet-24	338	14	j.	j.	PROPN
admet-24	338	15	amer	amer	PROPN
admet-24	338	16	.	.	PUNCT
admet-24	338	17	pharm	pharm	PROPN
admet-24	338	18	.	.	PUNCT
admet-24	339	1	assoc	assoc	PROPN
admet-24	339	2	.	.	PUNCT
admet-24	340	1	(	(	PUNCT
admet-24	340	2	sci	sci	PROPN
admet-24	340	3	.	.	PUNCT
admet-24	341	1	ed	ed	PROPN
admet-24	341	2	.	.	PUNCT
admet-24	341	3	)	)	PUNCT
admet-24	342	1	42	42	NUM
admet-24	342	2	(	(	PUNCT
admet-24	342	3	1953	1953	NUM
admet-24	342	4	)	)	PUNCT
admet-24	342	5	157	157	NUM
admet-24	342	6	-	-	SYM
admet-24	342	7	161	161	NUM
admet-24	342	8	.	.	PUNCT
admet-24	343	1	[	[	X
admet-24	343	2	10	10	NUM
admet-24	343	3	]	]	X
admet-24	343	4	t.j	t.j	PROPN
admet-24	343	5	.	.	PROPN
admet-24	343	6	roseman	roseman	PROPN
admet-24	343	7	,	,	PUNCT
admet-24	343	8	s.h	s.h	PROPN
admet-24	343	9	.	.	PROPN
admet-24	343	10	yalkowsky	yalkowsky	PROPN
admet-24	343	11	,	,	PUNCT
admet-24	343	12	j.	j.	PROPN
admet-24	343	13	pharm	pharm	PROPN
admet-24	343	14	.	.	PUNCT
admet-24	344	1	sci	sci	PROPN
admet-24	344	2	.	.	PROPN
admet-24	345	1	62	62	NUM
admet-24	345	2	(	(	PUNCT
admet-24	345	3	1973	1973	NUM
admet-24	345	4	)	)	PUNCT
admet-24	345	5	1680	1680	NUM
admet-24	345	6	-	-	SYM
admet-24	345	7	1685	1685	NUM
admet-24	345	8	.	.	PUNCT
admet-24	346	1	[	[	X
admet-24	346	2	11	11	NUM
admet-24	346	3	]	]	X
admet-24	346	4	d.j	d.j	PROPN
admet-24	346	5	.	.	PROPN
admet-24	346	6	attwood	attwood	PROPN
admet-24	346	7	,	,	PUNCT
admet-24	346	8	j.	j.	PROPN
admet-24	346	9	gibson	gibson	PROPN
admet-24	346	10	,	,	PUNCT
admet-24	346	11	j.	j.	PROPN
admet-24	346	12	pharm	pharm	PROPN
admet-24	346	13	.	.	PUNCT
admet-24	347	1	pharmacol	pharmacol	PROPN
admet-24	347	2	.	.	PROPN
admet-24	348	1	30	30	NUM
admet-24	348	2	(	(	PUNCT
admet-24	348	3	1978	1978	NUM
admet-24	348	4	)	)	PUNCT
admet-24	348	5	176	176	NUM
admet-24	348	6	-	-	SYM
admet-24	348	7	180	180	NUM
admet-24	348	8	.	.	PUNCT
admet-24	349	1	[	[	X
admet-24	349	2	12	12	NUM
admet-24	349	3	]	]	PUNCT
admet-24	349	4	a.	a.	NOUN
admet-24	349	5	fini	fini	PROPN
admet-24	349	6	,	,	PUNCT
admet-24	349	7	g.	g.	PROPN
admet-24	349	8	fazio	fazio	PROPN
admet-24	349	9	,	,	PUNCT
admet-24	349	10	g.	g.	PROPN
admet-24	349	11	feroci	feroci	PROPN
admet-24	349	12	,	,	PUNCT
admet-24	349	13	int	int	PROPN
admet-24	349	14	.	.	PUNCT
admet-24	350	1	j.	j.	PROPN
admet-24	350	2	pharm	pharm	PROPN
admet-24	350	3	.	.	PUNCT
admet-24	351	1	126	126	NUM
admet-24	351	2	(	(	PUNCT
admet-24	351	3	1995	1995	NUM
admet-24	351	4	)	)	PUNCT
admet-24	351	5	95	95	NUM
admet-24	351	6	-	-	SYM
admet-24	351	7	102	102	NUM
admet-24	351	8	.	.	PUNCT
admet-24	352	1	[	[	X
admet-24	352	2	13	13	NUM
admet-24	352	3	]	]	PUNCT
admet-24	352	4	z.	z.	PROPN
admet-24	352	5	wang	wang	PROPN
admet-24	352	6	,	,	PUNCT
admet-24	352	7	k.r	k.r	PROPN
admet-24	352	8	.	.	PROPN
admet-24	352	9	morris	morris	PROPN
admet-24	352	10	,	,	PUNCT
admet-24	352	11	b.	b.	PROPN
admet-24	352	12	chu	chu	PROPN
admet-24	352	13	,	,	PUNCT
admet-24	352	14	j.	j.	PROPN
admet-24	352	15	pharm	pharm	PROPN
admet-24	352	16	.	.	PUNCT
admet-24	353	1	sci	sci	PROPN
admet-24	353	2	.	.	PROPN
admet-24	354	1	84	84	NUM
admet-24	354	2	(	(	PUNCT
admet-24	354	3	1995	1995	NUM
admet-24	354	4	)	)	PUNCT
admet-24	354	5	609	609	NUM
admet-24	354	6	-	-	SYM
admet-24	354	7	613	613	NUM
admet-24	354	8	.	.	PUNCT
admet-24	355	1	[	[	X
admet-24	355	2	14	14	NUM
admet-24	355	3	]	]	X
admet-24	355	4	y.	y.	NOUN
admet-24	355	5	surakitbanharn	surakitbanharn	PROPN
admet-24	355	6	,	,	PUNCT
admet-24	355	7	r.	r.	PROPN
admet-24	355	8	mccandless	mccandless	PROPN
admet-24	355	9	,	,	PUNCT
admet-24	355	10	j.f	j.f	PROPN
admet-24	355	11	.	.	PROPN
admet-24	355	12	krzyzaniak	krzyzaniak	PROPN
admet-24	355	13	,	,	PUNCT
admet-24	355	14	r.-m	r.-m	PROPN
admet-24	355	15	.	.	PUNCT
admet-24	356	1	dannenfelser	dannenfelser	PROPN
admet-24	356	2	,	,	PUNCT
admet-24	356	3	s.h	s.h	PROPN
admet-24	356	4	.	.	PROPN
admet-24	356	5	yalkowsky	yalkowsky	PROPN
admet-24	356	6	,	,	PUNCT
admet-24	356	7	j.	j.	PROPN
admet-24	356	8	pharm	pharm	PROPN
admet-24	356	9	.	.	PUNCT
admet-24	357	1	sci	sci	PROPN
admet-24	357	2	.	.	PROPN
admet-24	358	1	84	84	NUM
admet-24	358	2	(	(	PUNCT
admet-24	358	3	1995	1995	NUM
admet-24	358	4	)	)	PUNCT
admet-24	358	5	720	720	NUM
admet-24	358	6	-	-	SYM
admet-24	358	7	723	723	NUM
admet-24	358	8	.	.	PUNCT
admet-24	359	1	[	[	X
admet-24	359	2	15	15	NUM
admet-24	359	3	]	]	X
admet-24	359	4	w.h	w.h	PROPN
admet-24	359	5	.	.	PROPN
admet-24	359	6	streng	streng	PROPN
admet-24	359	7	,	,	PUNCT
admet-24	359	8	d.h.-s	d.h.-s	PROPN
admet-24	359	9	.	.	NOUN
admet-24	359	10	yu	yu	PROPN
admet-24	359	11	,	,	PUNCT
admet-24	359	12	c.	c.	PROPN
admet-24	359	13	zhu	zhu	PROPN
admet-24	359	14	,	,	PUNCT
admet-24	359	15	int	int	NOUN
admet-24	359	16	.	.	PUNCT
admet-24	360	1	j.	j.	PROPN
admet-24	360	2	pharm	pharm	PROPN
admet-24	360	3	.	.	PUNCT
admet-24	361	1	135	135	NUM
admet-24	361	2	(	(	PUNCT
admet-24	361	3	1996	1996	NUM
admet-24	361	4	)	)	PUNCT
admet-24	361	5	43	43	NUM
admet-24	361	6	-	-	SYM
admet-24	361	7	52	52	NUM
admet-24	361	8	.	.	PUNCT
admet-24	362	1	[	[	X
admet-24	362	2	16	16	NUM
admet-24	362	3	]	]	PUNCT
admet-24	362	4	c.a.s	c.a.s	PROPN
admet-24	362	5	.	.	PROPN
admet-24	362	6	bergström	bergström	PROPN
admet-24	362	7	,	,	PUNCT
admet-24	362	8	k.	k.	PROPN
admet-24	362	9	luthman	luthman	PROPN
admet-24	362	10	,	,	PUNCT
admet-24	362	11	p.	p.	PROPN
admet-24	362	12	artursson	artursson	PROPN
admet-24	362	13	,	,	PUNCT
admet-24	362	14	eur	eur	PROPN
admet-24	362	15	.	.	PUNCT
admet-24	363	1	j.	j.	PROPN
admet-24	363	2	pharm	pharm	PROPN
admet-24	363	3	.	.	PUNCT
admet-24	364	1	sci	sci	PROPN
admet-24	364	2	.	.	PROPN
admet-24	365	1	22	22	NUM
admet-24	365	2	(	(	PUNCT
admet-24	365	3	2004	2004	NUM
admet-24	365	4	)	)	PUNCT
admet-24	365	5	387	387	NUM
admet-24	365	6	-	-	SYM
admet-24	365	7	398	398	NUM
admet-24	365	8	.	.	PUNCT
admet-24	366	1	[	[	X
admet-24	366	2	17	17	NUM
admet-24	366	3	]	]	PUNCT
admet-24	366	4	a.	a.	NOUN
admet-24	366	5	avdeef	avdeef	PROPN
admet-24	366	6	,	,	PUNCT
admet-24	366	7	adv	adv	PROPN
admet-24	366	8	.	.	PUNCT
admet-24	366	9	drug	drug	PROPN
admet-24	366	10	deliv	deliv	PROPN
admet-24	366	11	.	.	PUNCT
admet-24	367	1	rev	rev	PROPN
admet-24	367	2	.	.	PROPN
admet-24	367	3	59	59	NUM
admet-24	367	4	(	(	PUNCT
admet-24	367	5	2007	2007	NUM
admet-24	367	6	)	)	PUNCT
admet-24	367	7	568	568	NUM
admet-24	367	8	-	-	SYM
admet-24	367	9	590	590	NUM
admet-24	367	10	.	.	PUNCT
admet-24	368	1	[	[	X
admet-24	368	2	18	18	NUM
admet-24	368	3	]	]	X
admet-24	368	4	e.	e.	PROPN
admet-24	368	5	shoghi	shoghi	PROPN
admet-24	368	6	,	,	PUNCT
admet-24	368	7	e.	e.	PROPN
admet-24	368	8	fuguet	fuguet	PROPN
admet-24	368	9	,	,	PUNCT
admet-24	368	10	e.	e.	PROPN
admet-24	368	11	bosch	bosch	PROPN
admet-24	368	12	,	,	PUNCT
admet-24	368	13	c.	c.	PROPN
admet-24	368	14	ràfols	ràfols	PROPN
admet-24	368	15	,	,	PUNCT
admet-24	368	16	eur	eur	PROPN
admet-24	368	17	.	.	PUNCT
admet-24	369	1	j.	j.	PROPN
admet-24	369	2	pharm	pharm	PROPN
admet-24	369	3	.	.	PUNCT
admet-24	370	1	sci	sci	PROPN
admet-24	370	2	.	.	PROPN
admet-24	371	1	48	48	NUM
admet-24	371	2	(	(	PUNCT
admet-24	371	3	2013	2013	NUM
admet-24	371	4	)	)	PUNCT
admet-24	371	5	291	291	NUM
admet-24	371	6	-	-	SYM
admet-24	371	7	300	300	NUM
admet-24	371	8	.	.	PUNCT
admet-24	372	1	[	[	X
admet-24	372	2	19	19	NUM
admet-24	372	3	]	]	PUNCT
admet-24	372	4	a.	a.	NOUN
admet-24	372	5	avdeef	avdeef	PROPN
admet-24	372	6	,	,	PUNCT
admet-24	372	7	absorption	absorption	NOUN
admet-24	372	8	and	and	CCONJ
admet-24	372	9	drug	drug	NOUN
admet-24	372	10	development	development	NOUN
admet-24	372	11	,	,	PUNCT
admet-24	372	12	second	second	ADJ
admet-24	372	13	edition	edition	NOUN
admet-24	372	14	.	.	PUNCT
admet-24	373	1	wiley	wiley	PROPN
admet-24	373	2	-	-	PUNCT
admet-24	373	3	interscience	interscience	PROPN
admet-24	373	4	,	,	PUNCT
admet-24	373	5	hoboken	hoboken	PROPN
admet-24	373	6	,	,	PUNCT
admet-24	373	7	nj	nj	PROPN
admet-24	373	8	,	,	PUNCT
admet-24	373	9	2012	2012	NUM
admet-24	373	10	.	.	PUNCT
admet-24	374	1	[	[	X
admet-24	374	2	20	20	NUM
admet-24	374	3	]	]	PUNCT
admet-24	374	4	a.	a.	NOUN
admet-24	374	5	avdeef	avdeef	PROPN
admet-24	374	6	,	,	PUNCT
admet-24	374	7	j.j	j.j	PROPN
admet-24	374	8	.	.	PROPN
admet-24	374	9	bucher	bucher	PROPN
admet-24	374	10	,	,	PUNCT
admet-24	374	11	anal	anal	PROPN
admet-24	374	12	.	.	PUNCT
admet-24	375	1	chem	chem	PROPN
admet-24	375	2	.	.	PUNCT
admet-24	376	1	50	50	NUM
admet-24	376	2	(	(	PUNCT
admet-24	376	3	1978	1978	NUM
admet-24	376	4	)	)	PUNCT
admet-24	376	5	2137	2137	NUM
admet-24	376	6	-	-	SYM
admet-24	376	7	2142	2142	NUM
admet-24	376	8	.	.	PUNCT
admet-24	377	1	[	[	X
admet-24	377	2	21	21	NUM
admet-24	377	3	]	]	X
admet-24	377	4	e.	e.	PROPN
admet-24	377	5	baka	baka	PROPN
admet-24	377	6	,	,	PUNCT
admet-24	377	7	j.	j.	PROPN
admet-24	377	8	comer	comer	PROPN
admet-24	377	9	,	,	PUNCT
admet-24	377	10	k.	k.	PROPN
admet-24	377	11	takács	takács	PROPN
admet-24	377	12	-	-	PUNCT
admet-24	377	13	novák	novák	PROPN
admet-24	377	14	,	,	PUNCT
admet-24	377	15	j.	j.	PROPN
admet-24	377	16	pharm	pharm	PROPN
admet-24	377	17	.	.	PUNCT
admet-24	377	18	biomed	biome	VERB
admet-24	377	19	.	.	PUNCT
admet-24	378	1	anal	anal	ADJ
admet-24	378	2	.	.	PUNCT
admet-24	379	1	46	46	NUM
admet-24	379	2	(	(	PUNCT
admet-24	379	3	2008	2008	NUM
admet-24	379	4	)	)	PUNCT
admet-24	379	5	335	335	NUM
admet-24	379	6	-	-	SYM
admet-24	379	7	341	341	NUM
admet-24	379	8	.	.	PUNCT
admet-24	380	1	[	[	X
admet-24	380	2	22	22	NUM
admet-24	380	3	]	]	PUNCT
admet-24	380	4	a.	a.	NOUN
admet-24	380	5	avdeef	avdeef	PROPN
admet-24	380	6	,	,	PUNCT
admet-24	380	7	d.a	d.a	PROPN
admet-24	380	8	.	.	PROPN
admet-24	380	9	barrett	barrett	PROPN
admet-24	380	10	,	,	PUNCT
admet-24	380	11	p.n	p.n	PROPN
admet-24	380	12	.	.	PROPN
admet-24	380	13	shaw	shaw	PROPN
admet-24	380	14	,	,	PUNCT
admet-24	380	15	r.d	r.d	PROPN
admet-24	380	16	.	.	PROPN
admet-24	380	17	knaggs	knaggs	PROPN
admet-24	380	18	,	,	PUNCT
admet-24	380	19	s.s	s.s	PROPN
admet-24	380	20	.	.	PROPN
admet-24	380	21	davis	davis	PROPN
admet-24	380	22	,	,	PUNCT
admet-24	380	23	j.	j.	PROPN
admet-24	380	24	med	med	PROPN
admet-24	380	25	.	.	PROPN
admet-24	380	26	chem	chem	PROPN
admet-24	380	27	.	.	PUNCT
admet-24	381	1	39	39	NUM
admet-24	381	2	(	(	PUNCT
admet-24	381	3	1996	1996	NUM
admet-24	381	4	)	)	PUNCT
admet-24	381	5	4377	4377	NUM
admet-24	381	6	-	-	SYM
admet-24	381	7	4381	4381	NUM
admet-24	381	8	.	.	PUNCT
admet-24	382	1	[	[	X
admet-24	382	2	23	23	NUM
admet-24	382	3	]	]	PUNCT
admet-24	382	4	a.	a.	NOUN
admet-24	382	5	avdeef	avdeef	PROPN
admet-24	382	6	,	,	PUNCT
admet-24	382	7	k.j	k.j	PROPN
admet-24	382	8	.	.	PROPN
admet-24	382	9	box	box	PROPN
admet-24	382	10	,	,	PUNCT
admet-24	382	11	j.e.a	j.e.a	PROPN
admet-24	382	12	.	.	PUNCT
admet-24	382	13	comer	comer	PROPN
admet-24	382	14	,	,	PUNCT
admet-24	382	15	c.	c.	PROPN
admet-24	382	16	hibbert	hibbert	PROPN
admet-24	382	17	,	,	PUNCT
admet-24	382	18	k.y	k.y	PROPN
admet-24	382	19	.	.	PROPN
admet-24	382	20	tam	tam	PROPN
admet-24	382	21	,	,	PUNCT
admet-24	382	22	pharm	pharm	PROPN
admet-24	382	23	.	.	PUNCT
admet-24	383	1	res	re	NOUN
admet-24	383	2	.	.	PROPN
admet-24	384	1	15	15	NUM
admet-24	384	2	(	(	PUNCT
admet-24	384	3	1997	1997	NUM
admet-24	384	4	)	)	PUNCT
admet-24	384	5	208	208	NUM
admet-24	384	6	-	-	SYM
admet-24	384	7	214	214	NUM
admet-24	384	8	.	.	PUNCT
admet-24	385	1	[	[	X
admet-24	385	2	24	24	NUM
admet-24	385	3	]	]	X
admet-24	385	4	r.	r.	PROPN
admet-24	385	5	kuhne	kuhne	PROPN
admet-24	385	6	,	,	PUNCT
admet-24	385	7	r	r	PROPN
admet-24	385	8	-	-	PUNCT
admet-24	385	9	u.	u.	PROPN
admet-24	385	10	ebert	ebert	PROPN
admet-24	385	11	,	,	PUNCT
admet-24	385	12	f.	f.	PROPN
admet-24	385	13	kleint	kleint	PROPN
admet-24	385	14	,	,	PUNCT
admet-24	385	15	g.	g.	PROPN
admet-24	385	16	schmidt	schmidt	PROPN
admet-24	385	17	,	,	PUNCT
admet-24	385	18	g.	g.	PROPN
admet-24	385	19	schuurmann	schuurmann	PROPN
admet-24	385	20	,	,	PUNCT
admet-24	385	21	chemosphere	chemosphere	VERB
admet-24	385	22	30	30	NUM
admet-24	385	23	(	(	PUNCT
admet-24	385	24	1995	1995	NUM
admet-24	385	25	)	)	PUNCT
admet-24	385	26	2061	2061	NUM
admet-24	385	27	-	-	SYM
admet-24	385	28	2077	2077	NUM
admet-24	385	29	.	.	PUNCT
admet-24	386	1	[	[	X
admet-24	386	2	25	25	NUM
admet-24	386	3	]	]	X
admet-24	386	4	e.	e.	PROPN
admet-24	386	5	shoghi	shoghi	PROPN
admet-24	386	6	,	,	PUNCT
admet-24	386	7	e.	e.	PROPN
admet-24	386	8	fuguet	fuguet	PROPN
admet-24	386	9	,	,	PUNCT
admet-24	386	10	c.	c.	PROPN
admet-24	386	11	ràfols	ràfols	PROPN
admet-24	386	12	,	,	PUNCT
admet-24	386	13	e.	e.	PROPN
admet-24	386	14	bosch	bosch	PROPN
admet-24	386	15	,	,	PUNCT
admet-24	386	16	chem	chem	NOUN
admet-24	386	17	.	.	PUNCT
admet-24	387	1	biodivers	biodiver	NOUN
admet-24	387	2	.	.	PUNCT
admet-24	388	1	6	6	NUM
admet-24	388	2	(	(	PUNCT
admet-24	388	3	2009	2009	NUM
admet-24	388	4	)	)	PUNCT
admet-24	388	5	1789	1789	NUM
admet-24	388	6	-	-	SYM
admet-24	388	7	1795	1795	NUM
admet-24	388	8	.	.	PUNCT
admet-24	389	1	[	[	X
admet-24	389	2	26	26	NUM
admet-24	389	3	]	]	X
admet-24	389	4	c.m	c.m	PROPN
admet-24	389	5	.	.	PROPN
admet-24	389	6	wassvik	wassvik	PROPN
admet-24	389	7	,	,	PUNCT
admet-24	389	8	a.g	a.g	PROPN
admet-24	389	9	.	.	PROPN
admet-24	389	10	holmén	holmén	PROPN
admet-24	389	11	,	,	PUNCT
admet-24	389	12	r.	r.	PROPN
admet-24	389	13	draheim	draheim	PROPN
admet-24	389	14	,	,	PUNCT
admet-24	389	15	p.	p.	PROPN
admet-24	389	16	artursson	artursson	PROPN
admet-24	389	17	.	.	PUNCT
admet-24	390	1	logp	logp	NOUN
admet-24	390	2	-	-	PUNCT
admet-24	390	3	independent	independent	ADJ
admet-24	390	4	solubility	solubility	NOUN
admet-24	390	5	of	of	ADP
admet-24	390	6	drugs	drug	NOUN
admet-24	390	7	molecular	molecular	ADJ
admet-24	390	8	descriptors	descriptor	NOUN
admet-24	390	9	for	for	ADP
admet-24	390	10	solid	solid	ADJ
admet-24	390	11	-	-	PUNCT
admet-24	390	12	state	state	NOUN
admet-24	390	13	limited	limited	ADJ
admet-24	390	14	solubility	solubility	NOUN
admet-24	390	15	.	.	PUNCT
admet-24	391	1	in	in	ADP
admet-24	391	2	:	:	PUNCT
admet-24	391	3	c.m	c.m	NOUN
admet-24	391	4	.	.	PROPN
admet-24	391	5	wassvik	wassvik	NOUN
admet-24	391	6	.	.	PUNCT
admet-24	392	1	phd	phd	NOUN
admet-24	392	2	thesis	thesis	PROPN
admet-24	392	3	,	,	PUNCT
admet-24	392	4	univ	univ	PROPN
admet-24	392	5	.	.	PUNCT
admet-24	393	1	uppsala	uppsala	PROPN
admet-24	393	2	,	,	PUNCT
admet-24	393	3	2006	2006	NUM
admet-24	393	4	.	.	PUNCT
admet-24	394	1	[	[	X
admet-24	394	2	27	27	NUM
admet-24	394	3	]	]	X
admet-24	394	4	s.	s.	PROPN
admet-24	394	5	pinsuwan	pinsuwan	PROPN
admet-24	394	6	,	,	PUNCT
admet-24	394	7	p.b	p.b	PROPN
admet-24	394	8	.	.	PROPN
admet-24	394	9	myrdal	myrdal	PROPN
admet-24	394	10	,	,	PUNCT
admet-24	394	11	y.-c	y.-c	PROPN
admet-24	394	12	.	.	PUNCT
admet-24	395	1	lee	lee	PROPN
admet-24	395	2	,	,	PUNCT
admet-24	395	3	s.h	s.h	PROPN
admet-24	395	4	.	.	PROPN
admet-24	395	5	yalkowsky	yalkowsky	PROPN
admet-24	395	6	,	,	PUNCT
admet-24	395	7	chemosphere	chemosphere	VERB
admet-24	395	8	35	35	NUM
admet-24	395	9	(	(	PUNCT
admet-24	395	10	1997	1997	NUM
admet-24	395	11	)	)	PUNCT
admet-24	395	12	2503	2503	NUM
admet-24	395	13	-	-	SYM
admet-24	395	14	2513	2513	NUM
admet-24	395	15	.	.	PUNCT
admet-24	396	1	[	[	X
admet-24	396	2	28	28	NUM
admet-24	396	3	]	]	X
admet-24	396	4	g.	g.	PROPN
admet-24	396	5	völgyi	völgyi	PROPN
admet-24	396	6	,	,	PUNCT
admet-24	396	7	e.	e.	PROPN
admet-24	396	8	baka	baka	PROPN
admet-24	396	9	,	,	PUNCT
admet-24	396	10	k.	k.	PROPN
admet-24	396	11	box	box	PROPN
admet-24	396	12	,	,	PUNCT
admet-24	396	13	j.	j.	PROPN
admet-24	396	14	comer	comer	PROPN
admet-24	396	15	,	,	PUNCT
admet-24	396	16	k.	k.	PROPN
admet-24	396	17	takács	takács	PROPN
admet-24	396	18	-	-	PUNCT
admet-24	396	19	novák	novák	PROPN
admet-24	396	20	,	,	PUNCT
admet-24	396	21	anal	anal	NOUN
admet-24	396	22	.	.	PUNCT
admet-24	397	1	chim	chim	PROPN
admet-24	397	2	.	.	PUNCT
admet-24	398	1	acta	acta	PROPN
admet-24	398	2	673	673	NUM
admet-24	398	3	(	(	PUNCT
admet-24	398	4	2010	2010	NUM
admet-24	398	5	)	)	PUNCT
admet-24	398	6	40	40	NUM
admet-24	398	7	-	-	SYM
admet-24	398	8	46	46	NUM
admet-24	398	9	.	.	PUNCT
admet-24	399	1	[	[	X
admet-24	399	2	29	29	NUM
admet-24	399	3	]	]	X
admet-24	399	4	w.h	w.h	PROPN
admet-24	399	5	.	.	PROPN
admet-24	399	6	streng	streng	PROPN
admet-24	399	7	,	,	PUNCT
admet-24	399	8	s.k	s.k	PROPN
admet-24	399	9	.	.	PROPN
admet-24	399	10	hsi	hsi	PROPN
admet-24	399	11	,	,	PUNCT
admet-24	399	12	p.e	p.e	PROPN
admet-24	399	13	.	.	PROPN
admet-24	399	14	helms	helm	NOUN
admet-24	399	15	,	,	PUNCT
admet-24	399	16	h.g.h	h.g.h	NOUN
admet-24	399	17	.	.	PUNCT
admet-24	400	1	tan	tan	PROPN
admet-24	400	2	,	,	PUNCT
admet-24	400	3	j.	j.	PROPN
admet-24	400	4	pharm	pharm	PROPN
admet-24	400	5	.	.	PUNCT
admet-24	401	1	sci	sci	PROPN
admet-24	401	2	.	.	PROPN
admet-24	402	1	73	73	NUM
admet-24	402	2	(	(	PUNCT
admet-24	402	3	1984	1984	NUM
admet-24	402	4	)	)	PUNCT
admet-24	402	5	1679	1679	NUM
admet-24	402	6	-	-	SYM
admet-24	402	7	1684	1684	NUM
admet-24	402	8	.	.	PUNCT
admet-24	403	1	[	[	X
admet-24	403	2	30	30	NUM
admet-24	403	3	]	]	PUNCT
admet-24	403	4	a.	a.	NOUN
admet-24	403	5	avdeef	avdeef	PROPN
admet-24	403	6	,	,	PUNCT
admet-24	403	7	pharm	pharm	PROPN
admet-24	403	8	.	.	PUNCT
admet-24	404	1	pharmacol	pharmacol	PROPN
admet-24	404	2	.	.	PUNCT
admet-24	405	1	commun	commun	PROPN
admet-24	405	2	.	.	PUNCT
admet-24	406	1	4	4	NUM
admet-24	406	2	(	(	PUNCT
admet-24	406	3	1998	1998	NUM
admet-24	406	4	)	)	PUNCT
admet-24	406	5	165	165	NUM
admet-24	406	6	-	-	SYM
admet-24	406	7	178	178	NUM
admet-24	406	8	.	.	PUNCT
admet-24	407	1	[	[	X
admet-24	407	2	31	31	NUM
admet-24	407	3	]	]	X
admet-24	407	4	w.h	w.h	PROPN
admet-24	407	5	.	.	PROPN
admet-24	407	6	streng	streng	PROPN
admet-24	407	7	,	,	PUNCT
admet-24	407	8	int	int	PROPN
admet-24	407	9	.	.	PUNCT
admet-24	408	1	j.	j.	PROPN
admet-24	408	2	pharm	pharm	PROPN
admet-24	408	3	.	.	PUNCT
admet-24	409	1	186	186	NUM
admet-24	409	2	(	(	PUNCT
admet-24	409	3	1999	1999	NUM
admet-24	409	4	)	)	PUNCT
admet-24	409	5	137–140	137–140	NUM
admet-24	409	6	.	.	PUNCT
admet-24	410	1	[	[	X
admet-24	410	2	32	32	NUM
admet-24	410	3	]	]	PUNCT
admet-24	410	4	a.	a.	NOUN
admet-24	410	5	avdeef	avdeef	PROPN
admet-24	410	6	,	,	PUNCT
admet-24	410	7	j.	j.	PROPN
admet-24	410	8	pharm	pharm	PROPN
admet-24	410	9	.	.	PUNCT
admet-24	411	1	sci	sci	PROPN
admet-24	411	2	.	.	PROPN
admet-24	412	1	82	82	NUM
admet-24	412	2	(	(	PUNCT
admet-24	412	3	1993	1993	NUM
admet-24	412	4	)	)	PUNCT
admet-24	412	5	183	183	NUM
admet-24	412	6	-	-	SYM
admet-24	412	7	190	190	NUM
admet-24	412	8	.	.	PUNCT
admet-24	413	1	[	[	X
admet-24	413	2	33	33	NUM
admet-24	413	3	]	]	X
admet-24	413	4	r.h	r.h	PROPN
admet-24	413	5	.	.	PROPN
admet-24	413	6	stokes	stokes	PROPN
admet-24	413	7	,	,	PUNCT
admet-24	413	8	r.a	r.a	PROPN
admet-24	413	9	.	.	PROPN
admet-24	413	10	robinson	robinson	PROPN
admet-24	413	11	,	,	PUNCT
admet-24	413	12	j.	j.	PROPN
admet-24	413	13	amer	amer	PROPN
admet-24	413	14	.	.	PROPN
admet-24	413	15	chem	chem	PROPN
admet-24	413	16	.	.	PUNCT
admet-24	414	1	soc	soc	PROPN
admet-24	414	2	.	.	PUNCT
admet-24	415	1	70	70	NUM
admet-24	415	2	(	(	PUNCT
admet-24	415	3	1948	1948	NUM
admet-24	415	4	)	)	PUNCT
admet-24	415	5	1870	1870	NUM
admet-24	415	6	-	-	SYM
admet-24	415	7	1878	1878	NUM
admet-24	415	8	.	.	PUNCT
admet-24	416	1	[	[	X
admet-24	416	2	34	34	NUM
admet-24	416	3	]	]	SYM
admet-24	416	4	r.g	r.g	PROPN
admet-24	416	5	.	.	PROPN
admet-24	416	6	bates	bates	PROPN
admet-24	416	7	,	,	PUNCT
admet-24	416	8	b.r	b.r	PROPN
admet-24	416	9	.	.	PROPN
admet-24	416	10	staples	staple	NOUN
admet-24	416	11	,	,	PUNCT
admet-24	416	12	r.a	r.a	PROPN
admet-24	416	13	.	.	PROPN
admet-24	416	14	robinson	robinson	PROPN
admet-24	416	15	,	,	PUNCT
admet-24	416	16	anal	anal	PROPN
admet-24	416	17	.	.	PUNCT
admet-24	416	18	chem	chem	PROPN
admet-24	416	19	.	.	PUNCT
admet-24	417	1	42	42	NUM
admet-24	417	2	(	(	PUNCT
admet-24	417	3	1970	1970	NUM
admet-24	417	4	)	)	PUNCT
admet-24	417	5	867	867	NUM
admet-24	417	6	-	-	SYM
admet-24	417	7	871	871	NUM
admet-24	417	8	.	.	PUNCT
admet-24	418	1	[	[	X
admet-24	418	2	35	35	NUM
admet-24	418	3	]	]	X
admet-24	418	4	r.a	r.a	PROPN
admet-24	418	5	.	.	PROPN
admet-24	418	6	robinson	robinson	PROPN
admet-24	418	7	,	,	PUNCT
admet-24	418	8	r.g	r.g	PROPN
admet-24	418	9	.	.	PROPN
admet-24	418	10	bates	bate	NOUN
admet-24	418	11	,	,	PUNCT
admet-24	418	12	marine	marine	ADJ
admet-24	418	13	chem	chem	NOUN
admet-24	418	14	.	.	PUNCT
admet-24	419	1	6	6	NUM
admet-24	419	2	(	(	PUNCT
admet-24	419	3	1978	1978	NUM
admet-24	419	4	)	)	PUNCT
admet-24	419	5	327	327	NUM
admet-24	419	6	-	-	SYM
admet-24	419	7	333	333	NUM
admet-24	419	8	.	.	PUNCT
admet-24	420	1	[	[	X
admet-24	420	2	36	36	NUM
admet-24	420	3	]	]	X
admet-24	420	4	j.o’m	j.o’m	PROPN
admet-24	420	5	.	.	PUNCT
admet-24	420	6	bockris	bockris	PROPN
admet-24	420	7	,	,	PUNCT
admet-24	420	8	a.k.n	a.k.n	PROPN
admet-24	420	9	.	.	PUNCT
admet-24	420	10	reddy	reddy	PROPN
admet-24	420	11	,	,	PUNCT
admet-24	420	12	modern	modern	ADJ
admet-24	420	13	electrochemistry	electrochemistry	NOUN
admet-24	420	14	,	,	PUNCT
admet-24	420	15	vol	vol	NOUN
admet-24	420	16	.	.	NOUN
admet-24	420	17	1	1	NUM
admet-24	420	18	.	.	PUNCT
admet-24	420	19	plenum	plenum	PROPN
admet-24	420	20	publishing	publishing	PROPN
admet-24	420	21	corp	corp	PROPN
admet-24	420	22	.	.	PROPN
admet-24	420	23	,	,	PUNCT
admet-24	420	24	new	new	PROPN
admet-24	420	25	york	york	PROPN
admet-24	420	26	,	,	PUNCT
admet-24	420	27	ny	ny	PROPN
admet-24	420	28	,	,	PUNCT
admet-24	420	29	1973	1973	NUM
admet-24	420	30	.	.	PUNCT
admet-24	421	1	[	[	X
admet-24	421	2	37	37	NUM
admet-24	421	3	]	]	X
admet-24	421	4	r.a	r.a	PROPN
admet-24	421	5	.	.	PROPN
admet-24	421	6	robinson	robinson	PROPN
admet-24	421	7	,	,	PUNCT
admet-24	421	8	r.h	r.h	PROPN
admet-24	421	9	.	.	PROPN
admet-24	421	10	stokes	stokes	PROPN
admet-24	421	11	,	,	PUNCT
admet-24	421	12	electrolytic	electrolytic	ADJ
admet-24	421	13	solutions	solution	NOUN
admet-24	421	14	.	.	PUNCT
admet-24	422	1	2nd	2nd	ADJ
admet-24	422	2	revised	revise	VERB
admet-24	422	3	ed	ed	NOUN
admet-24	422	4	.	.	PUNCT
admet-24	422	5	dover	dover	PROPN
admet-24	422	6	publications	publications	PROPN
admet-24	422	7	,	,	PUNCT
admet-24	422	8	inc	inc	PROPN
admet-24	422	9	.	.	PROPN
admet-24	422	10	,	,	PUNCT
admet-24	422	11	mineola	mineola	PROPN
admet-24	422	12	,	,	PUNCT
admet-24	422	13	ny	ny	PROPN
admet-24	422	14	,	,	PUNCT
admet-24	422	15	2002	2002	NUM
admet-24	422	16	.	.	PUNCT
admet-24	423	1	[	[	X
admet-24	423	2	38	38	NUM
admet-24	423	3	]	]	PUNCT
admet-24	423	4	j.	j.	PROPN
admet-24	423	5	kielland	kielland	PROPN
admet-24	423	6	,	,	PUNCT
admet-24	423	7	j.	j.	PROPN
admet-24	423	8	amer	amer	PROPN
admet-24	423	9	.	.	PROPN
admet-24	423	10	chem	chem	PROPN
admet-24	423	11	.	.	PUNCT
admet-24	424	1	soc	soc	PROPN
admet-24	424	2	.	.	PUNCT
admet-24	425	1	59	59	NUM
admet-24	425	2	(	(	PUNCT
admet-24	425	3	1937)1675	1937)1675	NUM
admet-24	425	4	-	-	PUNCT
admet-24	425	5	1678	1678	NUM
admet-24	425	6	.	.	PUNCT
admet-24	426	1	©	©	PROPN
admet-24	426	2	2013	2013	NUM
admet-24	426	3	by	by	ADP
admet-24	426	4	the	the	DET
admet-24	426	5	authors	author	NOUN
admet-24	426	6	;	;	PUNCT
admet-24	426	7	licensee	licensee	PROPN
admet-24	426	8	iapc	iapc	PROPN
admet-24	426	9	,	,	PUNCT
admet-24	426	10	zagreb	zagreb	PROPN
admet-24	426	11	,	,	PUNCT
admet-24	426	12	croatia	croatia	PROPN
admet-24	426	13	.	.	PUNCT
admet-24	427	1	this	this	DET
admet-24	427	2	article	article	NOUN
admet-24	427	3	is	be	AUX
admet-24	427	4	an	an	DET
admet-24	427	5	open	open	ADJ
admet-24	427	6	-	-	PUNCT
admet-24	427	7	access	access	NOUN
admet-24	427	8	article	article	NOUN
admet-24	427	9	distributed	distribute	VERB
admet-24	427	10	under	under	ADP
admet-24	427	11	the	the	DET
admet-24	427	12	terms	term	NOUN
admet-24	427	13	and	and	CCONJ
admet-24	427	14	conditions	condition	NOUN
admet-24	427	15	of	of	ADP
admet-24	427	16	the	the	DET
admet-24	427	17	creative	creative	ADJ
admet-24	427	18	commons	common	NOUN
admet-24	427	19	attribution	attribution	NOUN
admet-24	427	20	license	license	NOUN
admet-24	427	21	(	(	PUNCT
admet-24	427	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-24	427	23	)	)	PUNCT
admet-24	427	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN