id	sid	tid	token	lemma	pos
admet-261	1	1	manuscript	manuscript	PROPN
admet-261	1	2	doi	doi	PROPN
admet-261	1	3	:	:	PUNCT
admet-261	1	4	10.5599	10.5599	NUM
admet-261	1	5	/	/	SYM
admet-261	1	6	admet.3.4.261	admet.3.4.261	PROPN
admet-261	1	7	296	296	NUM
admet-261	1	8	admet	admet	X
admet-261	1	9	&	&	CCONJ
admet-261	1	10	dmpk	dmpk	PROPN
admet-261	1	11	3(4	3(4	NUM
admet-261	1	12	)	)	PUNCT
admet-261	1	13	(	(	PUNCT
admet-261	1	14	2015	2015	NUM
admet-261	1	15	)	)	PUNCT
admet-261	1	16	296	296	NUM
admet-261	1	17	-	-	SYM
admet-261	1	18	297	297	NUM
admet-261	1	19	;	;	PUNCT
admet-261	1	20	doi	doi	NOUN
admet-261	1	21	:	:	PUNCT
admet-261	1	22	10.5599	10.5599	NUM
admet-261	1	23	/	/	SYM
admet-261	1	24	admet.3.4.261	admet.3.4.261	NOUN
admet-261	1	25	open	open	ADJ
admet-261	1	26	access	access	NOUN
admet-261	1	27	:	:	PUNCT
admet-261	1	28	issn	issn	PROPN
admet-261	1	29	:	:	PUNCT
admet-261	1	30	1848	1848	NUM
admet-261	1	31	-	-	SYM
admet-261	1	32	7718	7718	NUM
admet-261	1	33	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-261	1	34	editorial	editorial	NOUN
admet-261	1	35	pka	pka	PROPN
admet-261	1	36	values	value	NOUN
admet-261	1	37	in	in	ADP
admet-261	1	38	solubility	solubility	NOUN
admet-261	1	39	determination	determination	NOUN
admet-261	1	40	using	use	VERB
admet-261	1	41	the	the	DET
admet-261	1	42	hendersonhasselbalch	hendersonhasselbalch	PROPN
admet-261	1	43	equation	equation	NOUN
admet-261	1	44	derek	derek	PROPN
admet-261	1	45	reynolds	reynolds	PROPN
admet-261	1	46	and	and	CCONJ
admet-261	1	47	kin	kin	PROPN
admet-261	1	48	tam	tam	PROPN
admet-261	1	49	admet	admet	PROPN
admet-261	1	50	&	&	CCONJ
admet-261	1	51	dmpk	dmpk	PROPN
admet-261	1	52	editorial	editorial	PROPN
admet-261	1	53	board	board	NOUN
admet-261	1	54	,	,	PUNCT
admet-261	1	55	email	email	NOUN
admet-261	1	56	:	:	PUNCT
admet-261	1	57	admet_dmpk@iapchem.org	admet_dmpk@iapchem.org	PROPN
admet-261	1	58	.	.	PUNCT
admet-261	2	1	published	publish	VERB
admet-261	2	2	:	:	PUNCT
admet-261	2	3	december	december	PROPN
admet-261	2	4	30	30	NUM
admet-261	2	5	,	,	PUNCT
admet-261	2	6	2015	2015	NUM
admet-261	2	7	in	in	ADP
admet-261	2	8	this	this	DET
admet-261	2	9	journal	journal	NOUN
admet-261	2	10	we	we	PRON
admet-261	2	11	publish	publish	VERB
admet-261	2	12	only	only	ADV
admet-261	2	13	high	high	ADJ
admet-261	2	14	quality	quality	NOUN
admet-261	2	15	peer	peer	NOUN
admet-261	2	16	reviewed	review	VERB
admet-261	2	17	scientific	scientific	ADJ
admet-261	2	18	papers	paper	NOUN
admet-261	2	19	but	but	CCONJ
admet-261	2	20	sometimes	sometimes	ADV
admet-261	2	21	not	not	PART
admet-261	2	22	all	all	DET
admet-261	2	23	scientists	scientist	NOUN
admet-261	2	24	can	can	AUX
admet-261	2	25	agree	agree	VERB
admet-261	2	26	with	with	ADP
admet-261	2	27	all	all	DET
admet-261	2	28	aspects	aspect	NOUN
admet-261	2	29	of	of	ADP
admet-261	2	30	a	a	DET
admet-261	2	31	particular	particular	ADJ
admet-261	2	32	paper	paper	NOUN
admet-261	2	33	.	.	PUNCT
admet-261	3	1	we	we	PRON
admet-261	3	2	wish	wish	VERB
admet-261	3	3	to	to	PART
admet-261	3	4	encourage	encourage	VERB
admet-261	3	5	healthy	healthy	ADJ
admet-261	3	6	scientific	scientific	ADJ
admet-261	3	7	debate	debate	NOUN
admet-261	3	8	and	and	CCONJ
admet-261	3	9	when	when	SCONJ
admet-261	3	10	appropriate	appropriate	ADJ
admet-261	3	11	it	it	PRON
admet-261	3	12	is	be	AUX
admet-261	3	13	right	right	ADJ
admet-261	3	14	to	to	PART
admet-261	3	15	publish	publish	VERB
admet-261	3	16	alternative	alternative	ADJ
admet-261	3	17	interpretations	interpretation	NOUN
admet-261	3	18	of	of	ADP
admet-261	3	19	reported	report	VERB
admet-261	3	20	experiments	experiment	NOUN
admet-261	3	21	.	.	PUNCT
admet-261	4	1	alex	alex	PROPN
admet-261	4	2	avdeef	avdeef	PROPN
admet-261	5	1	[	[	X
admet-261	5	2	1	1	X
admet-261	5	3	]	]	PUNCT
admet-261	5	4	and	and	CCONJ
admet-261	5	5	samuel	samuel	PROPN
admet-261	5	6	yalkowsky	yalkowsky	PROPN
admet-261	5	7	[	[	X
admet-261	5	8	2	2	NUM
admet-261	5	9	]	]	PUNCT
admet-261	5	10	have	have	AUX
admet-261	5	11	independently	independently	ADV
admet-261	5	12	studied	study	VERB
admet-261	5	13	the	the	DET
admet-261	5	14	solubility	solubility	NOUN
admet-261	5	15	and	and	CCONJ
admet-261	5	16	ionization	ionization	NOUN
admet-261	5	17	properties	property	NOUN
admet-261	5	18	of	of	ADP
admet-261	5	19	an	an	DET
admet-261	5	20	investigational	investigational	ADJ
admet-261	5	21	drug	drug	NOUN
admet-261	5	22	(	(	PUNCT
admet-261	5	23	nsc-639829	nsc-639829	NOUN
admet-261	5	24	)	)	PUNCT
admet-261	5	25	.	.	PUNCT
admet-261	6	1	in	in	ADP
admet-261	6	2	the	the	DET
admet-261	6	3	study	study	NOUN
admet-261	6	4	conducted	conduct	VERB
admet-261	6	5	by	by	ADP
admet-261	6	6	avdeef	avdeef	NOUN
admet-261	6	7	and	and	CCONJ
admet-261	6	8	coworkers	coworker	NOUN
admet-261	6	9	,	,	PUNCT
admet-261	6	10	the	the	DET
admet-261	6	11	pka	pka	PROPN
admet-261	6	12	value	value	NOUN
admet-261	6	13	derived	derive	VERB
admet-261	6	14	from	from	ADP
admet-261	6	15	henderson	henderson	PROPN
admet-261	6	16	-	-	PUNCT
admet-261	6	17	hasselbalch	hasselbalch	PROPN
admet-261	6	18	(	(	PUNCT
admet-261	6	19	hh	hh	NOUN
admet-261	6	20	)	)	PUNCT
admet-261	6	21	equation	equation	NOUN
admet-261	6	22	was	be	AUX
admet-261	6	23	4.70	4.70	NUM
admet-261	6	24	,	,	PUNCT
admet-261	6	25	which	which	PRON
admet-261	6	26	was	be	AUX
admet-261	6	27	different	different	ADJ
admet-261	6	28	from	from	ADP
admet-261	6	29	the	the	DET
admet-261	6	30	value	value	NOUN
admet-261	6	31	of	of	ADP
admet-261	6	32	3.76	3.76	NUM
admet-261	6	33	as	as	SCONJ
admet-261	6	34	determined	determine	VERB
admet-261	6	35	experimentally	experimentally	ADV
admet-261	6	36	by	by	ADP
admet-261	6	37	the	the	DET
admet-261	6	38	yasuda	yasuda	NOUN
admet-261	6	39	-	-	PUNCT
admet-261	6	40	shedlovsky	shedlovsky	ADJ
admet-261	6	41	plot	plot	NOUN
admet-261	6	42	using	use	VERB
admet-261	6	43	the	the	DET
admet-261	6	44	pka	pka	PROPN
admet-261	6	45	values	value	NOUN
admet-261	6	46	obtained	obtain	VERB
admet-261	6	47	from	from	ADP
admet-261	6	48	co	co	ADJ
admet-261	6	49	-	-	ADJ
admet-261	6	50	solvent	solvent	ADJ
admet-261	6	51	uv	uv	NOUN
admet-261	6	52	titrations	titration	NOUN
admet-261	6	53	.	.	PUNCT
admet-261	7	1	the	the	DET
admet-261	7	2	authors	author	NOUN
admet-261	7	3	then	then	ADV
admet-261	7	4	invoked	invoke	VERB
admet-261	7	5	an	an	DET
admet-261	7	6	ionization	ionization	NOUN
admet-261	7	7	-	-	PUNCT
admet-261	7	8	precipitation	precipitation	NOUN
admet-261	7	9	-	-	PUNCT
admet-261	7	10	aggregation	aggregation	NOUN
admet-261	7	11	model	model	NOUN
admet-261	7	12	by	by	ADP
admet-261	7	13	assuming	assume	VERB
admet-261	7	14	the	the	DET
admet-261	7	15	formation	formation	NOUN
admet-261	7	16	of	of	ADP
admet-261	7	17	a	a	DET
admet-261	7	18	positively	positively	ADV
admet-261	7	19	charged	charge	VERB
admet-261	7	20	dimer	dimer	NOUN
admet-261	7	21	to	to	PART
admet-261	7	22	generate	generate	VERB
admet-261	7	23	the	the	DET
admet-261	7	24	theoretical	theoretical	ADJ
admet-261	7	25	solubility	solubility	NOUN
admet-261	7	26	-	-	PUNCT
admet-261	7	27	ph	ph	ADJ
admet-261	7	28	profile	profile	NOUN
admet-261	7	29	.	.	PUNCT
admet-261	8	1	in	in	ADP
admet-261	8	2	their	their	PRON
admet-261	8	3	implementation	implementation	NOUN
admet-261	8	4	,	,	PUNCT
admet-261	8	5	the	the	DET
admet-261	8	6	pka	pka	PROPN
admet-261	8	7	was	be	AUX
admet-261	8	8	fixed	fix	VERB
admet-261	8	9	at	at	ADP
admet-261	8	10	3.76	3.76	NUM
admet-261	8	11	,	,	PUNCT
admet-261	8	12	while	while	SCONJ
admet-261	8	13	the	the	DET
admet-261	8	14	s0	s0	PROPN
admet-261	8	15	,	,	PUNCT
admet-261	8	16	and	and	CCONJ
admet-261	8	17	the	the	DET
admet-261	8	18	aggregation	aggregation	NOUN
admet-261	8	19	equilibrium	equilibrium	NOUN
admet-261	8	20	constant	constant	ADJ
admet-261	8	21	were	be	AUX
admet-261	8	22	treated	treat	VERB
admet-261	8	23	as	as	ADP
admet-261	8	24	adjustable	adjustable	ADJ
admet-261	8	25	parameters	parameter	NOUN
admet-261	8	26	.	.	PUNCT
admet-261	9	1	to	to	ADP
admet-261	9	2	this	this	DET
admet-261	9	3	end	end	NOUN
admet-261	9	4	,	,	PUNCT
admet-261	9	5	the	the	DET
admet-261	9	6	authors	author	NOUN
admet-261	9	7	obtained	obtain	VERB
admet-261	9	8	a	a	DET
admet-261	9	9	reasonably	reasonably	ADV
admet-261	9	10	good	good	ADJ
admet-261	9	11	fit	fit	NOUN
admet-261	9	12	between	between	ADP
admet-261	9	13	the	the	DET
admet-261	9	14	model	model	NOUN
admet-261	9	15	and	and	CCONJ
admet-261	9	16	the	the	DET
admet-261	9	17	experiment	experiment	NOUN
admet-261	9	18	.	.	PUNCT
admet-261	10	1	the	the	DET
admet-261	10	2	s0	s0	PROPN
admet-261	10	3	value	value	NOUN
admet-261	10	4	as	as	SCONJ
admet-261	10	5	determined	determine	VERB
admet-261	10	6	using	use	VERB
admet-261	10	7	this	this	DET
admet-261	10	8	approach	approach	NOUN
admet-261	10	9	appeared	appear	VERB
admet-261	10	10	to	to	PART
admet-261	10	11	be	be	AUX
admet-261	10	12	in	in	ADP
admet-261	10	13	line	line	NOUN
admet-261	10	14	with	with	ADP
admet-261	10	15	the	the	DET
admet-261	10	16	previously	previously	ADV
admet-261	10	17	reported	report	VERB
admet-261	10	18	value	value	NOUN
admet-261	10	19	[	[	X
admet-261	10	20	2	2	NUM
admet-261	10	21	]	]	PUNCT
admet-261	10	22	.	.	PUNCT
admet-261	11	1	in	in	ADP
admet-261	11	2	this	this	DET
admet-261	11	3	issue	issue	NOUN
admet-261	11	4	,	,	PUNCT
admet-261	11	5	yalkowsky	yalkowsky	PROPN
admet-261	11	6	et	et	PROPN
admet-261	11	7	al	al	PROPN
admet-261	11	8	.	.	PUNCT
admet-261	12	1	[	[	X
admet-261	12	2	3	3	X
admet-261	12	3	]	]	PUNCT
admet-261	12	4	published	publish	VERB
admet-261	12	5	a	a	DET
admet-261	12	6	note	note	NOUN
admet-261	12	7	to	to	PART
admet-261	12	8	comment	comment	VERB
admet-261	12	9	on	on	ADP
admet-261	12	10	the	the	DET
admet-261	12	11	approach	approach	NOUN
admet-261	12	12	that	that	PRON
admet-261	12	13	avdeef	avdeef	VERB
admet-261	12	14	et	et	PROPN
admet-261	12	15	al	al	PROPN
admet-261	12	16	.	.	PUNCT
admet-261	13	1	[	[	X
admet-261	13	2	1	1	X
admet-261	13	3	]	]	PUNCT
admet-261	13	4	developed	develop	VERB
admet-261	13	5	in	in	ADP
admet-261	13	6	the	the	DET
admet-261	13	7	study	study	NOUN
admet-261	13	8	of	of	ADP
admet-261	13	9	nsc-639829	nsc-639829	NOUN
admet-261	13	10	.	.	PUNCT
admet-261	14	1	in	in	ADP
admet-261	14	2	particular	particular	ADJ
admet-261	14	3	,	,	PUNCT
admet-261	14	4	they	they	PRON
admet-261	14	5	have	have	AUX
admet-261	14	6	pointed	point	VERB
admet-261	14	7	out	out	ADP
admet-261	14	8	that	that	SCONJ
admet-261	14	9	the	the	DET
admet-261	14	10	pka	pka	NOUN
admet-261	14	11	of	of	ADP
admet-261	14	12	4.70	4.70	NUM
admet-261	14	13	for	for	ADP
admet-261	14	14	nsc639829	nsc639829	NOUN
admet-261	14	15	was	be	AUX
admet-261	14	16	the	the	DET
admet-261	14	17	correct	correct	ADJ
admet-261	14	18	value	value	NOUN
admet-261	14	19	in	in	ADP
admet-261	14	20	the	the	DET
admet-261	14	21	solubility	solubility	NOUN
admet-261	14	22	determination	determination	NOUN
admet-261	14	23	study	study	NOUN
admet-261	14	24	,	,	PUNCT
admet-261	14	25	and	and	CCONJ
admet-261	14	26	the	the	DET
admet-261	14	27	analysis	analysis	NOUN
admet-261	14	28	carried	carry	VERB
admet-261	14	29	out	out	ADP
admet-261	14	30	by	by	ADP
admet-261	14	31	avdeef	avdeef	PROPN
admet-261	14	32	et	et	PROPN
admet-261	14	33	al	al	PROPN
admet-261	14	34	.	.	PUNCT
admet-261	15	1	[	[	X
admet-261	15	2	1	1	X
admet-261	15	3	]	]	PUNCT
admet-261	15	4	was	be	AUX
admet-261	15	5	problematical	problematical	ADJ
admet-261	15	6	.	.	PUNCT
admet-261	16	1	yalkowsky	yalkowsky	ADJ
admet-261	16	2	et	et	PROPN
admet-261	16	3	al	al	PROPN
admet-261	16	4	.	.	PROPN
admet-261	16	5	have	have	AUX
admet-261	16	6	highlighted	highlight	VERB
admet-261	16	7	that	that	SCONJ
admet-261	16	8	pka	pka	PROPN
admet-261	16	9	is	be	AUX
admet-261	16	10	a	a	DET
admet-261	16	11	concentration	concentration	NOUN
admet-261	16	12	dependent	dependent	ADJ
admet-261	16	13	parameter	parameter	NOUN
admet-261	16	14	,	,	PUNCT
admet-261	16	15	which	which	PRON
admet-261	16	16	was	be	AUX
admet-261	16	17	supported	support	VERB
admet-261	16	18	by	by	ADP
admet-261	16	19	several	several	ADJ
admet-261	16	20	literature	literature	NOUN
admet-261	16	21	examples	example	NOUN
admet-261	16	22	[	[	X
admet-261	16	23	3	3	NUM
admet-261	16	24	]	]	PUNCT
admet-261	16	25	.	.	PUNCT
admet-261	17	1	apparently	apparently	ADV
admet-261	17	2	,	,	PUNCT
admet-261	17	3	yalkowsky	yalkowsky	AUX
admet-261	17	4	et	et	PROPN
admet-261	17	5	al	al	PROPN
admet-261	17	6	.	.	PROPN
admet-261	17	7	have	have	AUX
admet-261	17	8	put	put	VERB
admet-261	17	9	forward	forward	ADV
admet-261	17	10	some	some	DET
admet-261	17	11	compelling	compelling	ADJ
admet-261	17	12	arguments	argument	NOUN
admet-261	17	13	to	to	PART
admet-261	17	14	justify	justify	VERB
admet-261	17	15	their	their	PRON
admet-261	17	16	points	point	NOUN
admet-261	17	17	of	of	ADP
admet-261	17	18	view	view	NOUN
admet-261	17	19	in	in	ADP
admet-261	17	20	case	case	NOUN
admet-261	17	21	of	of	ADP
admet-261	17	22	nsc-639829	nsc-639829	NOUN
admet-261	17	23	.	.	PUNCT
admet-261	18	1	generally	generally	ADV
admet-261	18	2	speaking	speak	VERB
admet-261	18	3	,	,	PUNCT
admet-261	18	4	pka	pka	PROPN
admet-261	18	5	is	be	AUX
admet-261	18	6	not	not	PART
admet-261	18	7	an	an	DET
admet-261	18	8	absolute	absolute	ADJ
admet-261	18	9	molecular	molecular	ADJ
admet-261	18	10	constant	constant	ADJ
admet-261	18	11	because	because	SCONJ
admet-261	18	12	it	it	PRON
admet-261	18	13	depends	depend	VERB
admet-261	18	14	very	very	ADV
admet-261	18	15	much	much	ADV
admet-261	18	16	on	on	ADP
admet-261	18	17	the	the	DET
admet-261	18	18	medium	medium	ADJ
admet-261	18	19	,	,	PUNCT
admet-261	18	20	conditions	condition	NOUN
admet-261	18	21	and	and	CCONJ
admet-261	18	22	ionic	ionic	ADJ
admet-261	18	23	strength	strength	NOUN
admet-261	18	24	of	of	ADP
admet-261	18	25	determination	determination	NOUN
admet-261	18	26	.	.	PUNCT
admet-261	19	1	for	for	ADP
admet-261	19	2	low	low	ADJ
admet-261	19	3	sample	sample	NOUN
admet-261	19	4	concentration	concentration	NOUN
admet-261	19	5	and/or	and/or	CCONJ
admet-261	19	6	in	in	ADP
admet-261	19	7	the	the	DET
admet-261	19	8	presence	presence	NOUN
admet-261	19	9	of	of	ADP
admet-261	19	10	cosolvent	cosolvent	NOUN
admet-261	19	11	,	,	PUNCT
admet-261	19	12	the	the	DET
admet-261	19	13	formation	formation	NOUN
admet-261	19	14	of	of	ADP
admet-261	19	15	aggregate	aggregate	NOUN
admet-261	19	16	in	in	ADP
admet-261	19	17	pka	pka	PROPN
admet-261	19	18	determination	determination	NOUN
admet-261	19	19	is	be	AUX
admet-261	19	20	less	less	ADV
admet-261	19	21	favorable	favorable	ADJ
admet-261	19	22	.	.	PUNCT
admet-261	20	1	in	in	ADP
admet-261	20	2	case	case	NOUN
admet-261	20	3	of	of	ADP
admet-261	20	4	nsc-639829	nsc-639829	NOUN
admet-261	20	5	,	,	PUNCT
admet-261	20	6	the	the	DET
admet-261	20	7	pka	pka	PROPN
admet-261	20	8	determination	determination	NOUN
admet-261	20	9	was	be	AUX
admet-261	20	10	accomplished	accomplish	VERB
admet-261	20	11	by	by	ADP
admet-261	20	12	long	long	ADJ
admet-261	20	13	range	range	NOUN
admet-261	20	14	extrapolation	extrapolation	NOUN
admet-261	20	15	from	from	ADP
admet-261	20	16	co	co	ADJ
admet-261	20	17	-	-	ADJ
admet-261	20	18	solvent	solvent	ADJ
admet-261	20	19	pka	pka	PROPN
admet-261	20	20	data	datum	NOUN
admet-261	20	21	(	(	PUNCT
admet-261	20	22	22	22	NUM
admet-261	20	23	-	-	SYM
admet-261	20	24	41	41	NUM
admet-261	20	25	%	%	NOUN
admet-261	20	26	methanolwater	methanolwater	NOUN
admet-261	20	27	mixtures	mixture	NOUN
admet-261	20	28	)	)	PUNCT
admet-261	21	1	[	[	X
admet-261	21	2	1	1	NUM
admet-261	21	3	]	]	PUNCT
admet-261	21	4	.	.	PUNCT
admet-261	22	1	again	again	ADV
admet-261	22	2	,	,	PUNCT
admet-261	22	3	this	this	PRON
admet-261	22	4	may	may	AUX
admet-261	22	5	introduce	introduce	VERB
admet-261	22	6	some	some	DET
admet-261	22	7	uncertainty	uncertainty	NOUN
admet-261	22	8	to	to	ADP
admet-261	22	9	the	the	DET
admet-261	22	10	extrapolated	extrapolated	ADJ
admet-261	22	11	pka	pka	PROPN
admet-261	22	12	value	value	NOUN
admet-261	22	13	.	.	PUNCT
admet-261	23	1	it	it	PRON
admet-261	23	2	may	may	AUX
admet-261	23	3	be	be	AUX
admet-261	23	4	difficult	difficult	ADJ
admet-261	23	5	to	to	PART
admet-261	23	6	make	make	VERB
admet-261	23	7	direct	direct	ADJ
admet-261	23	8	comparison	comparison	NOUN
admet-261	23	9	between	between	ADP
admet-261	23	10	the	the	DET
admet-261	23	11	pka	pka	PROPN
admet-261	23	12	determined	determine	VERB
admet-261	23	13	independently	independently	ADV
admet-261	23	14	and	and	CCONJ
admet-261	23	15	the	the	DET
admet-261	23	16	pka	pka	PROPN
admet-261	23	17	derived	derive	VERB
admet-261	23	18	from	from	ADP
admet-261	23	19	the	the	DET
admet-261	23	20	hh	hh	PROPN
admet-261	23	21	equation	equation	NOUN
admet-261	23	22	since	since	SCONJ
admet-261	23	23	the	the	DET
admet-261	23	24	chemical	chemical	PROPN
admet-261	23	25	/	/	SYM
admet-261	23	26	physical	physical	ADJ
admet-261	23	27	environments	environment	NOUN
admet-261	23	28	are	be	AUX
admet-261	23	29	unlikely	unlikely	ADJ
admet-261	23	30	to	to	PART
admet-261	23	31	be	be	AUX
admet-261	23	32	the	the	DET
admet-261	23	33	same	same	ADJ
admet-261	23	34	in	in	ADP
admet-261	23	35	these	these	DET
admet-261	23	36	two	two	NUM
admet-261	23	37	experiments	experiment	NOUN
admet-261	23	38	.	.	PUNCT
admet-261	24	1	in	in	ADP
admet-261	24	2	our	our	PRON
admet-261	24	3	opinion	opinion	NOUN
admet-261	24	4	,	,	PUNCT
admet-261	24	5	avdeef	avdeef	PROPN
admet-261	24	6	et	et	PROPN
admet-261	24	7	al	al	PROPN
admet-261	24	8	.	.	PUNCT
admet-261	25	1	[	[	X
admet-261	25	2	1	1	X
admet-261	25	3	]	]	PUNCT
admet-261	25	4	have	have	AUX
admet-261	25	5	developed	develop	VERB
admet-261	25	6	very	very	ADV
admet-261	25	7	powerful	powerful	ADJ
admet-261	25	8	software	software	NOUN
admet-261	25	9	to	to	PART
admet-261	25	10	analyze	analyze	VERB
admet-261	25	11	complex	complex	ADJ
admet-261	25	12	ionizationprecipitation	ionizationprecipitation	NOUN
admet-261	25	13	-	-	PUNCT
admet-261	25	14	aggregation	aggregation	NOUN
admet-261	25	15	system	system	NOUN
admet-261	25	16	,	,	PUNCT
admet-261	25	17	which	which	PRON
admet-261	25	18	we	we	PRON
admet-261	25	19	should	should	AUX
admet-261	25	20	applaud	applaud	VERB
admet-261	25	21	.	.	PUNCT
admet-261	26	1	on	on	ADP
admet-261	26	2	the	the	DET
admet-261	26	3	other	other	ADJ
admet-261	26	4	hand	hand	NOUN
admet-261	26	5	,	,	PUNCT
admet-261	26	6	yalkowsky	yalkowsky	ADJ
admet-261	26	7	et	et	PROPN
admet-261	26	8	al	al	PROPN
admet-261	26	9	.	.	PROPN
admet-261	26	10	pointed	point	VERB
admet-261	26	11	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-261	26	12	mailto:admet_dmpk@iapchem.org	mailto:admet_dmpk@iapchem.org	PROPN
admet-261	26	13	admet	admet	PROPN
admet-261	26	14	&	&	CCONJ
admet-261	26	15	dmpk	dmpk	PROPN
admet-261	26	16	3(4	3(4	NUM
admet-261	26	17	)	)	PUNCT
admet-261	26	18	(	(	PUNCT
admet-261	26	19	2015	2015	NUM
admet-261	26	20	)	)	PUNCT
admet-261	26	21	296	296	NUM
admet-261	26	22	-	-	SYM
admet-261	26	23	297	297	NUM
admet-261	26	24	editorial	editorial	NOUN
admet-261	26	25	on	on	ADP
admet-261	26	26	henderson	henderson	PROPN
admet-261	26	27	-	-	PUNCT
admet-261	26	28	hasselbalh	hasselbalh	PROPN
admet-261	26	29	equation	equation	NOUN
admet-261	26	30	doi	doi	NOUN
admet-261	26	31	:	:	PUNCT
admet-261	26	32	10.5599	10.5599	NUM
admet-261	26	33	/	/	SYM
admet-261	26	34	admet.3.4.261	admet.3.4.261	PROPN
admet-261	26	35	297	297	NUM
admet-261	26	36	out	out	ADP
admet-261	26	37	that	that	SCONJ
admet-261	26	38	effectively	effectively	ADV
admet-261	26	39	what	what	PRON
admet-261	26	40	the	the	DET
admet-261	26	41	software	software	NOUN
admet-261	26	42	does	do	AUX
admet-261	26	43	in	in	ADP
admet-261	26	44	the	the	DET
admet-261	26	45	case	case	NOUN
admet-261	26	46	of	of	ADP
admet-261	26	47	nsc-639829	nsc-639829	NOUN
admet-261	26	48	was	be	AUX
admet-261	26	49	adding	add	VERB
admet-261	26	50	an	an	DET
admet-261	26	51	arbitrary	arbitrary	ADJ
admet-261	26	52	factor	factor	NOUN
admet-261	26	53	of	of	ADP
admet-261	26	54	0.94	0.94	NUM
admet-261	26	55	to	to	PART
admet-261	26	56	bring	bring	VERB
admet-261	26	57	the	the	DET
admet-261	26	58	pka	pka	NOUN
admet-261	26	59	to	to	ADP
admet-261	26	60	4.70	4.70	NUM
admet-261	26	61	.	.	PUNCT
admet-261	27	1	we	we	PRON
admet-261	27	2	see	see	VERB
admet-261	27	3	that	that	SCONJ
admet-261	27	4	these	these	PRON
admet-261	27	5	are	be	AUX
admet-261	27	6	just	just	ADV
admet-261	27	7	two	two	NUM
admet-261	27	8	different	different	ADJ
admet-261	27	9	approaches	approach	NOUN
admet-261	27	10	to	to	PART
admet-261	27	11	interpret	interpret	VERB
admet-261	27	12	the	the	DET
admet-261	27	13	same	same	ADJ
admet-261	27	14	dataset	dataset	NOUN
admet-261	27	15	.	.	PUNCT
admet-261	28	1	perhaps	perhaps	ADV
admet-261	28	2	the	the	DET
admet-261	28	3	aggregate	aggregate	ADJ
admet-261	28	4	formation	formation	NOUN
admet-261	28	5	may	may	AUX
admet-261	28	6	well	well	ADV
admet-261	28	7	be	be	AUX
admet-261	28	8	true	true	ADJ
admet-261	28	9	as	as	SCONJ
admet-261	28	10	proposed	propose	VERB
admet-261	28	11	by	by	ADP
admet-261	28	12	avdeef	avdeef	PROPN
admet-261	28	13	et	et	PROPN
admet-261	28	14	al	al	PROPN
admet-261	28	15	.	.	PUNCT
admet-261	29	1	[	[	X
admet-261	29	2	1	1	NUM
admet-261	29	3	]	]	PUNCT
admet-261	29	4	.	.	PUNCT
admet-261	30	1	however	however	ADV
admet-261	30	2	,	,	PUNCT
admet-261	30	3	it	it	PRON
admet-261	30	4	is	be	AUX
admet-261	30	5	always	always	ADV
admet-261	30	6	difficult	difficult	ADJ
admet-261	30	7	to	to	PART
admet-261	30	8	prove	prove	VERB
admet-261	30	9	the	the	DET
admet-261	30	10	formation	formation	NOUN
admet-261	30	11	of	of	ADP
admet-261	30	12	the	the	DET
admet-261	30	13	positively	positively	ADV
admet-261	30	14	charged	charge	VERB
admet-261	30	15	dimer	dimer	NOUN
admet-261	30	16	in	in	ADP
admet-261	30	17	the	the	DET
admet-261	30	18	equilibrium	equilibrium	NOUN
admet-261	30	19	model	model	NOUN
admet-261	30	20	solely	solely	ADV
admet-261	30	21	based	base	VERB
admet-261	30	22	on	on	ADP
admet-261	30	23	mass	mass	NOUN
admet-261	30	24	balance	balance	NOUN
admet-261	30	25	calculation	calculation	NOUN
admet-261	30	26	.	.	PUNCT
admet-261	31	1	to	to	PART
admet-261	31	2	confirm	confirm	VERB
admet-261	31	3	the	the	DET
admet-261	31	4	validity	validity	NOUN
admet-261	31	5	of	of	ADP
admet-261	31	6	the	the	DET
admet-261	31	7	model	model	NOUN
admet-261	31	8	,	,	PUNCT
admet-261	31	9	it	it	PRON
admet-261	31	10	is	be	AUX
admet-261	31	11	necessary	necessary	ADJ
admet-261	31	12	to	to	PART
admet-261	31	13	obtain	obtain	VERB
admet-261	31	14	independent	independent	ADJ
admet-261	31	15	structural	structural	ADJ
admet-261	31	16	or	or	CCONJ
admet-261	31	17	spectroscopic	spectroscopic	ADJ
admet-261	31	18	evidence	evidence	NOUN
admet-261	31	19	.	.	PUNCT
admet-261	32	1	although	although	SCONJ
admet-261	32	2	this	this	DET
admet-261	32	3	discussion	discussion	NOUN
admet-261	32	4	centers	center	VERB
admet-261	32	5	around	around	ADP
admet-261	32	6	just	just	ADV
admet-261	32	7	one	one	NUM
admet-261	32	8	compound	compound	NOUN
admet-261	32	9	it	it	PRON
admet-261	32	10	is	be	AUX
admet-261	32	11	part	part	NOUN
admet-261	32	12	of	of	ADP
admet-261	32	13	a	a	DET
admet-261	32	14	wider	wide	ADJ
admet-261	32	15	debate	debate	NOUN
admet-261	32	16	regarding	regard	VERB
admet-261	32	17	the	the	DET
admet-261	32	18	applicability	applicability	NOUN
admet-261	32	19	of	of	ADP
admet-261	32	20	the	the	DET
admet-261	32	21	hh	hh	PROPN
admet-261	32	22	equation	equation	NOUN
admet-261	32	23	to	to	ADP
admet-261	32	24	the	the	DET
admet-261	32	25	study	study	NOUN
admet-261	32	26	of	of	ADP
admet-261	32	27	solubility	solubility	NOUN
admet-261	32	28	where	where	SCONJ
admet-261	32	29	complications	complication	NOUN
admet-261	32	30	are	be	AUX
admet-261	32	31	likely	likely	ADJ
admet-261	32	32	to	to	PART
admet-261	32	33	arise	arise	VERB
admet-261	32	34	due	due	ADP
admet-261	32	35	to	to	ADP
admet-261	32	36	presence	presence	NOUN
admet-261	32	37	of	of	ADP
admet-261	32	38	aggregate	aggregate	ADJ
admet-261	32	39	species	specie	NOUN
admet-261	32	40	in	in	ADP
admet-261	32	41	solution	solution	NOUN
admet-261	32	42	.	.	PUNCT
admet-261	33	1	all	all	DET
admet-261	33	2	the	the	DET
admet-261	33	3	authors	author	NOUN
admet-261	33	4	of	of	ADP
admet-261	33	5	these	these	DET
admet-261	33	6	papers	paper	NOUN
admet-261	33	7	have	have	AUX
admet-261	33	8	made	make	VERB
admet-261	33	9	significant	significant	ADJ
admet-261	33	10	contributions	contribution	NOUN
admet-261	33	11	to	to	ADP
admet-261	33	12	the	the	DET
admet-261	33	13	field	field	NOUN
admet-261	33	14	.	.	PUNCT
admet-261	34	1	we	we	PRON
admet-261	34	2	hope	hope	VERB
admet-261	34	3	that	that	SCONJ
admet-261	34	4	many	many	ADJ
admet-261	34	5	scientists	scientist	NOUN
admet-261	34	6	with	with	ADP
admet-261	34	7	an	an	DET
admet-261	34	8	interest	interest	NOUN
admet-261	34	9	in	in	ADP
admet-261	34	10	solubility	solubility	NOUN
admet-261	34	11	and	and	CCONJ
admet-261	34	12	ionization	ionization	NOUN
admet-261	34	13	will	will	AUX
admet-261	34	14	read	read	VERB
admet-261	34	15	both	both	DET
admet-261	34	16	papers	paper	NOUN
admet-261	34	17	and	and	CCONJ
admet-261	34	18	learn	learn	VERB
admet-261	34	19	from	from	ADP
admet-261	34	20	the	the	DET
admet-261	34	21	differing	differ	VERB
admet-261	34	22	views	view	NOUN
admet-261	34	23	of	of	ADP
admet-261	34	24	these	these	DET
admet-261	34	25	eminent	eminent	ADJ
admet-261	34	26	researchers	researcher	NOUN
admet-261	34	27	.	.	PUNCT
admet-261	35	1	references	reference	NOUN
admet-261	35	2	[	[	X
admet-261	35	3	1	1	NUM
admet-261	35	4	]	]	PUNCT
admet-261	35	5	g.	g.	NOUN
admet-261	35	6	butcher	butcher	PROPN
admet-261	35	7	,	,	PUNCT
admet-261	35	8	j.	j.	PROPN
admet-261	35	9	comer	comer	PROPN
admet-261	35	10	,	,	PUNCT
admet-261	35	11	a.	a.	NOUN
admet-261	35	12	avdeef	avdeef	PROPN
admet-261	35	13	,	,	PUNCT
admet-261	35	14	admet	admet	PROPN
admet-261	35	15	&	&	CCONJ
admet-261	35	16	dmpk	dmpk	PROPN
admet-261	35	17	3(2	3(2	NUM
admet-261	35	18	)	)	PUNCT
admet-261	35	19	(	(	PUNCT
admet-261	35	20	2015	2015	NUM
admet-261	35	21	)	)	PUNCT
admet-261	35	22	131	131	NUM
admet-261	35	23	-	-	SYM
admet-261	35	24	140	140	NUM
admet-261	35	25	.	.	PUNCT
admet-261	36	1	[	[	X
admet-261	36	2	2	2	NUM
admet-261	36	3	]	]	X
admet-261	36	4	n.	n.	PROPN
admet-261	36	5	jain	jain	PROPN
admet-261	36	6	,	,	PUNCT
admet-261	36	7	g.	g.	PROPN
admet-261	36	8	yang	yang	PROPN
admet-261	36	9	,	,	PUNCT
admet-261	36	10	s.e	s.e	PROPN
admet-261	36	11	.	.	PROPN
admet-261	36	12	tabibi	tabibi	NOUN
admet-261	36	13	,	,	PUNCT
admet-261	36	14	s.h	s.h	PROPN
admet-261	36	15	.	.	NOUN
admet-261	36	16	yalkowsky	yalkowsky	ADJ
admet-261	36	17	,	,	PUNCT
admet-261	36	18	int	int	NOUN
admet-261	36	19	.	.	PUNCT
admet-261	37	1	j.	j.	PROPN
admet-261	37	2	pharm	pharm	PROPN
admet-261	37	3	.	.	PUNCT
admet-261	38	1	225	225	NUM
admet-261	38	2	(	(	PUNCT
admet-261	38	3	2001	2001	NUM
admet-261	38	4	)	)	PUNCT
admet-261	38	5	41	41	NUM
admet-261	38	6	-	-	SYM
admet-261	38	7	47	47	NUM
admet-261	38	8	.	.	PUNCT
admet-261	39	1	[	[	X
admet-261	39	2	3	3	X
admet-261	39	3	]	]	PUNCT
admet-261	39	4	s.	s.	PROPN
admet-261	39	5	yalkowsky	yalkowsky	PROPN
admet-261	39	6	,	,	PUNCT
admet-261	39	7	r.	r.	PROPN
admet-261	39	8	patel	patel	PROPN
admet-261	39	9	,	,	PUNCT
admet-261	39	10	d.	d.	PROPN
admet-261	39	11	al	al	PROPN
admet-261	39	12	-	-	PUNCT
admet-261	39	13	antary	antary	ADJ
admet-261	39	14	,	,	PUNCT
admet-261	39	15	admet	admet	PROPN
admet-261	39	16	&	&	CCONJ
admet-261	39	17	dmpk	dmpk	PROPN
admet-261	39	18	3(4	3(4	NUM
admet-261	39	19	)	)	PUNCT
admet-261	39	20	(	(	PUNCT
admet-261	39	21	2015	2015	NUM
admet-261	39	22	)	)	PUNCT
admet-261	39	23	358	358	NUM
admet-261	39	24	-	-	SYM
admet-261	39	25	361	361	NUM
admet-261	39	26	.	.	PUNCT
admet-261	40	1	©	©	PROPN
admet-261	40	2	2015	2015	NUM
admet-261	40	3	by	by	ADP
admet-261	40	4	the	the	DET
admet-261	40	5	authors	author	NOUN
admet-261	40	6	;	;	PUNCT
admet-261	40	7	licensee	licensee	PROPN
admet-261	40	8	iapc	iapc	PROPN
admet-261	40	9	,	,	PUNCT
admet-261	40	10	zagreb	zagreb	PROPN
admet-261	40	11	,	,	PUNCT
admet-261	40	12	croatia	croatia	PROPN
admet-261	40	13	.	.	PUNCT
admet-261	41	1	this	this	DET
admet-261	41	2	article	article	NOUN
admet-261	41	3	is	be	AUX
admet-261	41	4	an	an	DET
admet-261	41	5	open	open	ADJ
admet-261	41	6	-	-	PUNCT
admet-261	41	7	access	access	NOUN
admet-261	41	8	article	article	NOUN
admet-261	41	9	distributed	distribute	VERB
admet-261	41	10	under	under	ADP
admet-261	41	11	the	the	DET
admet-261	41	12	terms	term	NOUN
admet-261	41	13	and	and	CCONJ
admet-261	41	14	conditions	condition	NOUN
admet-261	41	15	of	of	ADP
admet-261	41	16	the	the	DET
admet-261	41	17	creative	creative	ADJ
admet-261	41	18	commons	common	NOUN
admet-261	41	19	attribution	attribution	NOUN
admet-261	41	20	license	license	NOUN
admet-261	41	21	(	(	PUNCT
admet-261	41	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-261	41	23	)	)	PUNCT
admet-261	41	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN