id	sid	tid	token	lemma	pos
admet-2684	1	1	insight	insight	NOUN
admet-2684	1	2	into	into	ADP
admet-2684	1	3	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	1	4	effect	effect	NOUN
admet-2684	1	5	of	of	ADP
admet-2684	1	6	chlorinated	chlorinate	VERB
admet-2684	1	7	1	1	NUM
admet-2684	1	8	-	-	PUNCT
admet-2684	1	9	hydroxy	hydroxy	VERB
admet-2684	1	10	-	-	PUNCT
admet-2684	1	11	naphthalene-2	naphthalene-2	NUM
admet-2684	1	12	-	-	PUNCT
admet-2684	1	13	carboxanilides	carboxanilide	NOUN
admet-2684	1	14	doi	doi	NOUN
admet-2684	1	15	:	:	PUNCT
admet-2684	1	16	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	1	17	1	1	NUM
admet-2684	1	18	admet	admet	X
admet-2684	1	19	&	&	CCONJ
admet-2684	1	20	dmpk	dmpk	PROPN
admet-2684	1	21	13(2	13(2	PROPN
admet-2684	1	22	)	)	PUNCT
admet-2684	1	23	(	(	PUNCT
admet-2684	1	24	2025	2025	NUM
admet-2684	1	25	)	)	PUNCT
admet-2684	1	26	2684	2684	NUM
admet-2684	1	27	;	;	PUNCT
admet-2684	1	28	doi	doi	NOUN
admet-2684	1	29	:	:	PUNCT
admet-2684	1	30	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	1	31	open	open	ADJ
admet-2684	1	32	access	access	NOUN
admet-2684	1	33	:	:	PUNCT
admet-2684	1	34	issn	issn	PROPN
admet-2684	1	35	:	:	PUNCT
admet-2684	1	36	1848	1848	NUM
admet-2684	1	37	-	-	SYM
admet-2684	1	38	7718	7718	NUM
admet-2684	1	39	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-2684	1	40	original	original	ADJ
admet-2684	1	41	scientific	scientific	ADJ
admet-2684	1	42	paper	paper	NOUN
admet-2684	1	43	insight	insight	NOUN
admet-2684	1	44	into	into	ADP
admet-2684	1	45	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	1	46	effect	effect	NOUN
admet-2684	1	47	of	of	ADP
admet-2684	1	48	chlorinated	chlorinate	VERB
admet-2684	1	49	1	1	NUM
admet-2684	1	50	-	-	PUNCT
admet-2684	1	51	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	1	52	-	-	PUNCT
admet-2684	1	53	carboxanilides	carboxanilide	NOUN
admet-2684	1	54	lucia	lucia	PROPN
admet-2684	1	55	vrablova1	vrablova1	PROPN
admet-2684	1	56	,	,	PUNCT
admet-2684	1	57	tomas	tomas	PROPN
admet-2684	1	58	gonec2	gonec2	PROPN
admet-2684	1	59	,	,	PUNCT
admet-2684	1	60	petra	petra	PROPN
admet-2684	1	61	majerova3	majerova3	PROPN
admet-2684	1	62	,	,	PUNCT
admet-2684	1	63	andrej	andrej	PROPN
admet-2684	1	64	kovac3	kovac3	PROPN
admet-2684	1	65	,	,	PUNCT
admet-2684	1	66	dominika	dominika	PROPN
admet-2684	1	67	kos4	kos4	PROPN
admet-2684	1	68	,	,	PUNCT
admet-2684	1	69	peter	peter	PROPN
admet-2684	1	70	kollar5	kollar5	PROPN
admet-2684	1	71	,	,	PUNCT
admet-2684	1	72	jiri	jiri	PROPN
admet-2684	1	73	kos6	kos6	PROPN
admet-2684	1	74	,	,	PUNCT
admet-2684	1	75	alois	alois	PROPN
admet-2684	1	76	cizek7	cizek7	PROPN
admet-2684	1	77	,	,	PUNCT
admet-2684	1	78	tereza	tereza	PROPN
admet-2684	1	79	kauerova5	kauerova5	PROPN
admet-2684	1	80	,	,	PUNCT
admet-2684	1	81	*	*	PUNCT
admet-2684	1	82	and	and	CCONJ
admet-2684	1	83	josef	josef	PROPN
admet-2684	1	84	jampilek1,8,	jampilek1,8,	PROPN
admet-2684	1	85	1department	1department	NUM
admet-2684	1	86	of	of	ADP
admet-2684	1	87	analytical	analytical	ADJ
admet-2684	1	88	chemistry	chemistry	NOUN
admet-2684	1	89	,	,	PUNCT
admet-2684	1	90	faculty	faculty	NOUN
admet-2684	1	91	of	of	ADP
admet-2684	1	92	natural	natural	ADJ
admet-2684	1	93	sciences	science	NOUN
admet-2684	1	94	,	,	PUNCT
admet-2684	1	95	comenius	comenius	NOUN
admet-2684	1	96	university	university	NOUN
admet-2684	1	97	,	,	PUNCT
admet-2684	1	98	ilkovicova	ilkovicova	X
admet-2684	1	99	6	6	NUM
admet-2684	1	100	,	,	PUNCT
admet-2684	1	101	842	842	NUM
admet-2684	1	102	15	15	NUM
admet-2684	1	103	bratislava	bratislava	NOUN
admet-2684	1	104	,	,	PUNCT
admet-2684	1	105	slovakia	slovakia	PROPN
admet-2684	1	106	2department	2department	NUM
admet-2684	1	107	of	of	ADP
admet-2684	1	108	chemical	chemical	ADJ
admet-2684	1	109	drugs	drug	NOUN
admet-2684	1	110	,	,	PUNCT
admet-2684	1	111	faculty	faculty	NOUN
admet-2684	1	112	of	of	ADP
admet-2684	1	113	pharmacy	pharmacy	NOUN
admet-2684	1	114	,	,	PUNCT
admet-2684	1	115	masaryk	masaryk	PROPN
admet-2684	1	116	university	university	NOUN
admet-2684	1	117	,	,	PUNCT
admet-2684	1	118	palackeho	palackeho	VERB
admet-2684	1	119	tr	tr	VERB
admet-2684	1	120	.	.	NOUN
admet-2684	1	121	1946/1	1946/1	NUM
admet-2684	1	122	,	,	PUNCT
admet-2684	1	123	612	612	NUM
admet-2684	1	124	00	00	NUM
admet-2684	1	125	brno	brno	NOUN
admet-2684	1	126	,	,	PUNCT
admet-2684	1	127	czech	czech	PROPN
admet-2684	1	128	republic	republic	NOUN
admet-2684	1	129	3institute	3institute	NUM
admet-2684	1	130	of	of	ADP
admet-2684	1	131	neuroimmunology	neuroimmunology	NOUN
admet-2684	1	132	,	,	PUNCT
admet-2684	1	133	slovak	slovak	ADJ
admet-2684	1	134	academy	academy	NOUN
admet-2684	1	135	of	of	ADP
admet-2684	1	136	sciences	sciences	PROPN
admet-2684	1	137	,	,	PUNCT
admet-2684	1	138	dubravska	dubravska	NOUN
admet-2684	1	139	cesta	cesta	PROPN
admet-2684	1	140	9	9	NUM
admet-2684	1	141	,	,	PUNCT
admet-2684	1	142	845	845	NUM
admet-2684	1	143	10	10	NUM
admet-2684	1	144	bratislava	bratislava	NOUN
admet-2684	1	145	,	,	PUNCT
admet-2684	1	146	slovakia	slovakia	PROPN
admet-2684	1	147	4department	4department	NUM
admet-2684	1	148	of	of	ADP
admet-2684	1	149	molecular	molecular	ADJ
admet-2684	1	150	pharmacy	pharmacy	NOUN
admet-2684	1	151	,	,	PUNCT
admet-2684	1	152	faculty	faculty	NOUN
admet-2684	1	153	of	of	ADP
admet-2684	1	154	pharmacy	pharmacy	NOUN
admet-2684	1	155	,	,	PUNCT
admet-2684	1	156	masaryk	masaryk	PROPN
admet-2684	1	157	university	university	NOUN
admet-2684	1	158	,	,	PUNCT
admet-2684	1	159	palackeho	palackeho	VERB
admet-2684	1	160	tr	tr	VERB
admet-2684	1	161	.	.	NOUN
admet-2684	1	162	1946/1	1946/1	NUM
admet-2684	1	163	,	,	PUNCT
admet-2684	1	164	612	612	NUM
admet-2684	1	165	00	00	NUM
admet-2684	1	166	brno	brno	NOUN
admet-2684	1	167	,	,	PUNCT
admet-2684	1	168	czech	czech	PROPN
admet-2684	1	169	republic	republic	NOUN
admet-2684	1	170	5department	5department	NUM
admet-2684	1	171	of	of	ADP
admet-2684	1	172	pharmacology	pharmacology	NOUN
admet-2684	1	173	and	and	CCONJ
admet-2684	1	174	toxicology	toxicology	NOUN
admet-2684	1	175	,	,	PUNCT
admet-2684	1	176	faculty	faculty	NOUN
admet-2684	1	177	of	of	ADP
admet-2684	1	178	pharmacy	pharmacy	NOUN
admet-2684	1	179	,	,	PUNCT
admet-2684	1	180	masaryk	masaryk	PROPN
admet-2684	1	181	university	university	NOUN
admet-2684	1	182	,	,	PUNCT
admet-2684	1	183	palackeho	palackeho	VERB
admet-2684	1	184	tr	tr	VERB
admet-2684	1	185	.	.	NOUN
admet-2684	1	186	1946/1	1946/1	NUM
admet-2684	1	187	,	,	PUNCT
admet-2684	1	188	612	612	NUM
admet-2684	1	189	00	00	NUM
admet-2684	1	190	brno	brno	NOUN
admet-2684	1	191	,	,	PUNCT
admet-2684	1	192	czech	czech	PROPN
admet-2684	1	193	republic	republic	NOUN
admet-2684	1	194	6department	6department	NUM
admet-2684	1	195	of	of	ADP
admet-2684	1	196	biochemistry	biochemistry	NOUN
admet-2684	1	197	,	,	PUNCT
admet-2684	1	198	faculty	faculty	NOUN
admet-2684	1	199	of	of	ADP
admet-2684	1	200	medicine	medicine	NOUN
admet-2684	1	201	,	,	PUNCT
admet-2684	1	202	masaryk	masaryk	PROPN
admet-2684	1	203	university	university	NOUN
admet-2684	1	204	,	,	PUNCT
admet-2684	1	205	kamenice	kamenice	NOUN
admet-2684	1	206	5	5	NUM
admet-2684	1	207	,	,	PUNCT
admet-2684	1	208	brno	brno	NOUN
admet-2684	1	209	625	625	NUM
admet-2684	1	210	00	00	NUM
admet-2684	1	211	,	,	PUNCT
admet-2684	1	212	czech	czech	PROPN
admet-2684	1	213	republic	republic	NOUN
admet-2684	1	214	7department	7department	NUM
admet-2684	1	215	of	of	ADP
admet-2684	1	216	infectious	infectious	ADJ
admet-2684	1	217	diseases	disease	NOUN
admet-2684	1	218	and	and	CCONJ
admet-2684	1	219	microbiology	microbiology	NOUN
admet-2684	1	220	,	,	PUNCT
admet-2684	1	221	faculty	faculty	NOUN
admet-2684	1	222	of	of	ADP
admet-2684	1	223	veterinary	veterinary	ADJ
admet-2684	1	224	medicine	medicine	NOUN
admet-2684	1	225	,	,	PUNCT
admet-2684	1	226	university	university	NOUN
admet-2684	1	227	of	of	ADP
admet-2684	1	228	veterinary	veterinary	ADJ
admet-2684	1	229	sciences	science	NOUN
admet-2684	1	230	brno	brno	NOUN
admet-2684	1	231	,	,	PUNCT
admet-2684	1	232	palackeho	palackeho	VERB
admet-2684	1	233	tr	tr	VERB
admet-2684	1	234	.	.	NOUN
admet-2684	1	235	1946/1	1946/1	NUM
admet-2684	1	236	,	,	PUNCT
admet-2684	1	237	612	612	NUM
admet-2684	1	238	42	42	NUM
admet-2684	1	239	brno	brno	NOUN
admet-2684	1	240	,	,	PUNCT
admet-2684	1	241	czech	czech	PROPN
admet-2684	1	242	republic	republic	NOUN
admet-2684	1	243	8institute	8institute	NUM
admet-2684	1	244	of	of	ADP
admet-2684	1	245	chemistry	chemistry	NOUN
admet-2684	1	246	,	,	PUNCT
admet-2684	1	247	university	university	PROPN
admet-2684	1	248	of	of	ADP
admet-2684	1	249	silesia	silesia	PROPN
admet-2684	1	250	,	,	PUNCT
admet-2684	1	251	szkolna	szkolna	PROPN
admet-2684	1	252	9	9	NUM
admet-2684	1	253	,	,	PUNCT
admet-2684	1	254	40	40	NUM
admet-2684	1	255	-	-	SYM
admet-2684	1	256	006	006	NUM
admet-2684	1	257	katowice	katowice	NOUN
admet-2684	1	258	,	,	PUNCT
admet-2684	1	259	poland	poland	PROPN
admet-2684	1	260	corresponding	correspond	VERB
admet-2684	1	261	authors	author	NOUN
admet-2684	1	262	:	:	PUNCT
admet-2684	1	263	e	e	X
admet-2684	1	264	-	-	NOUN
admet-2684	1	265	mails	mail	NOUN
admet-2684	1	266	:	:	PUNCT
admet-2684	1	267	*	*	PUNCT
admet-2684	1	268	kauerovat@pharm.muni.cz	kauerovat@pharm.muni.cz	NOUN
admet-2684	1	269	;	;	PUNCT
admet-2684	1	270	josef.jampilek@gmail.com	josef.jampilek@gmail.com	X
admet-2684	1	271	received	receive	VERB
admet-2684	1	272	:	:	PUNCT
admet-2684	1	273	january	january	PROPN
admet-2684	1	274	18	18	NUM
admet-2684	1	275	,	,	PUNCT
admet-2684	1	276	2025	2025	NUM
admet-2684	1	277	;	;	PUNCT
admet-2684	1	278	revised	revise	VERB
admet-2684	1	279	:	:	PUNCT
admet-2684	1	280	march	march	PROPN
admet-2684	1	281	19	19	NUM
admet-2684	1	282	,	,	PUNCT
admet-2684	1	283	2025	2025	NUM
admet-2684	1	284	;	;	PUNCT
admet-2684	1	285	published	publish	VERB
admet-2684	1	286	:	:	PUNCT
admet-2684	1	287	march	march	PROPN
admet-2684	1	288	26	26	NUM
admet-2684	1	289	2025	2025	NUM
admet-2684	1	290	abstract	abstract	ADJ
admet-2684	1	291	background	background	NOUN
admet-2684	1	292	and	and	CCONJ
admet-2684	1	293	purpose	purpose	NOUN
admet-2684	1	294	:	:	PUNCT
admet-2684	1	295	new	new	ADJ
admet-2684	1	296	compounds	compound	NOUN
admet-2684	1	297	and	and	CCONJ
admet-2684	1	298	innovative	innovative	ADJ
admet-2684	1	299	therapeutic	therapeutic	ADJ
admet-2684	1	300	approaches	approach	NOUN
admet-2684	1	301	are	be	AUX
admet-2684	1	302	trying	try	VERB
admet-2684	1	303	to	to	PART
admet-2684	1	304	prevent	prevent	VERB
admet-2684	1	305	antimicrobial	antimicrobial	ADJ
admet-2684	1	306	resistance	resistance	NOUN
admet-2684	1	307	,	,	PUNCT
admet-2684	1	308	which	which	PRON
admet-2684	1	309	has	have	AUX
admet-2684	1	310	become	become	VERB
admet-2684	1	311	a	a	DET
admet-2684	1	312	global	global	ADJ
admet-2684	1	313	health	health	NOUN
admet-2684	1	314	challenge	challenge	NOUN
admet-2684	1	315	.	.	PUNCT
admet-2684	2	1	experimental	experimental	ADJ
admet-2684	2	2	approach	approach	NOUN
admet-2684	2	3	:	:	PUNCT
admet-2684	2	4	this	this	DET
admet-2684	2	5	study	study	NOUN
admet-2684	2	6	includes	include	VERB
admet-2684	2	7	a	a	DET
admet-2684	2	8	series	series	NOUN
admet-2684	2	9	of	of	ADP
admet-2684	2	10	twelve	twelve	NUM
admet-2684	2	11	mono-	mono-	NUM
admet-2684	2	12	,	,	PUNCT
admet-2684	2	13	diand	diand	NOUN
admet-2684	2	14	trichlorinated	trichlorinate	VERB
admet-2684	2	15	1	1	NUM
admet-2684	2	16	-	-	PUNCT
admet-2684	2	17	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	2	18	-	-	PUNCT
admet-2684	2	19	carboxanilides	carboxanilide	NOUN
admet-2684	2	20	designed	design	VERB
admet-2684	2	21	as	as	ADP
admet-2684	2	22	multitarget	multitarget	PROPN
admet-2684	2	23	agents	agent	NOUN
admet-2684	2	24	.	.	PUNCT
admet-2684	3	1	all	all	DET
admet-2684	3	2	compounds	compound	NOUN
admet-2684	3	3	were	be	AUX
admet-2684	3	4	evaluated	evaluate	VERB
admet-2684	3	5	for	for	ADP
admet-2684	3	6	their	their	PRON
admet-2684	3	7	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	3	8	activity	activity	NOUN
admet-2684	3	9	.	.	PUNCT
admet-2684	4	1	furthermore	furthermore	ADV
admet-2684	4	2	,	,	PUNCT
admet-2684	4	3	mtt	mtt	NOUN
admet-2684	4	4	assay	assay	VERB
admet-2684	4	5	and	and	CCONJ
admet-2684	4	6	chemoproteomic	chemoproteomic	ADJ
admet-2684	4	7	analysis	analysis	NOUN
admet-2684	4	8	of	of	ADP
admet-2684	4	9	selected	select	VERB
admet-2684	4	10	compounds	compound	NOUN
admet-2684	4	11	were	be	AUX
admet-2684	4	12	performed	perform	VERB
admet-2684	4	13	.	.	PUNCT
admet-2684	5	1	cytotoxicity	cytotoxicity	NOUN
admet-2684	5	2	in	in	ADP
admet-2684	5	3	human	human	ADJ
admet-2684	5	4	cells	cell	NOUN
admet-2684	5	5	was	be	AUX
admet-2684	5	6	also	also	ADV
admet-2684	5	7	tested	test	VERB
admet-2684	5	8	.	.	PUNCT
admet-2684	6	1	key	key	ADJ
admet-2684	6	2	results	result	NOUN
admet-2684	6	3	:	:	PUNCT
admet-2684	6	4	n-(3,5	n-(3,5	NOUN
admet-2684	6	5	-	-	PUNCT
admet-2684	6	6	dichlorophenyl)-1	dichlorophenyl)-1	PROPN
admet-2684	6	7	-	-	PUNCT
admet-2684	6	8	hydroxynaphthalene-2	hydroxynaphthalene-2	NOUN
admet-2684	6	9	-	-	PUNCT
admet-2684	6	10	carboxamide	carboxamide	NOUN
admet-2684	6	11	(	(	PUNCT
admet-2684	6	12	10	10	NUM
admet-2684	6	13	)	)	PUNCT
admet-2684	6	14	demonstrated	demonstrate	VERB
admet-2684	6	15	activity	activity	NOUN
admet-2684	6	16	comparable	comparable	ADJ
admet-2684	6	17	to	to	ADP
admet-2684	6	18	or	or	CCONJ
admet-2684	6	19	higher	high	ADJ
admet-2684	6	20	than	than	ADP
admet-2684	6	21	clinically	clinically	ADV
admet-2684	6	22	used	use	VERB
admet-2684	6	23	drugs	drug	NOUN
admet-2684	6	24	,	,	PUNCT
admet-2684	6	25	with	with	ADP
admet-2684	6	26	minimum	minimum	ADJ
admet-2684	6	27	inhibitory	inhibitory	ADJ
admet-2684	6	28	concentrations	concentration	NOUN
admet-2684	6	29	(	(	PUNCT
admet-2684	6	30	mics	mic	NOUN
admet-2684	6	31	)	)	PUNCT
admet-2684	6	32	of	of	ADP
admet-2684	6	33	0.37	0.37	NUM
admet-2684	6	34	μm	μm	NOUN
admet-2684	6	35	.	.	PUNCT
admet-2684	7	1	the	the	DET
admet-2684	7	2	compound	compound	NOUN
admet-2684	7	3	was	be	AUX
admet-2684	7	4	equally	equally	ADV
admet-2684	7	5	effective	effective	ADJ
admet-2684	7	6	against	against	ADP
admet-2684	7	7	clinical	clinical	ADJ
admet-2684	7	8	isolates	isolate	NOUN
admet-2684	7	9	of	of	ADP
admet-2684	7	10	methicillin	methicillin	NOUN
admet-2684	7	11	-	-	PUNCT
admet-2684	7	12	resistant	resistant	ADJ
admet-2684	7	13	s.	s.	PROPN
admet-2684	7	14	aureus	aureus	PROPN
admet-2684	7	15	.	.	PUNCT
admet-2684	8	1	on	on	ADP
admet-2684	8	2	the	the	DET
admet-2684	8	3	other	other	ADJ
admet-2684	8	4	hand	hand	NOUN
admet-2684	8	5	,	,	PUNCT
admet-2684	8	6	compound	compound	NOUN
admet-2684	8	7	10	10	NUM
admet-2684	8	8	showed	show	VERB
admet-2684	8	9	96	96	NUM
admet-2684	8	10	%	%	NOUN
admet-2684	8	11	inhibition	inhibition	NOUN
admet-2684	8	12	of	of	ADP
admet-2684	8	13	s.	s.	PROPN
admet-2684	8	14	aureus	aureus	PROPN
admet-2684	8	15	respiration	respiration	NOUN
admet-2684	8	16	only	only	ADV
admet-2684	8	17	at	at	ADP
admet-2684	8	18	a	a	DET
admet-2684	8	19	concentration	concentration	NOUN
admet-2684	8	20	of	of	ADP
admet-2684	8	21	16×	16×	NUM
admet-2684	8	22	mic	mic	ADJ
admet-2684	8	23	.	.	PUNCT
admet-2684	9	1	chemoproteomic	chemoproteomic	ADJ
admet-2684	9	2	analysis	analysis	NOUN
admet-2684	9	3	revealed	reveal	VERB
admet-2684	9	4	that	that	SCONJ
admet-2684	9	5	the	the	DET
admet-2684	9	6	effect	effect	NOUN
admet-2684	9	7	of	of	ADP
admet-2684	9	8	agent	agent	NOUN
admet-2684	9	9	10	10	NUM
admet-2684	9	10	on	on	ADP
admet-2684	9	11	staphylococci	staphylococci	PROPN
admet-2684	9	12	resulted	result	VERB
admet-2684	9	13	in	in	ADP
admet-2684	9	14	the	the	DET
admet-2684	9	15	downregulation	downregulation	NOUN
admet-2684	9	16	of	of	ADP
admet-2684	9	17	four	four	NUM
admet-2684	9	18	proteins	protein	NOUN
admet-2684	9	19	.	.	PUNCT
admet-2684	10	1	this	this	DET
admet-2684	10	2	compound	compound	NOUN
admet-2684	10	3	expressed	express	VERB
admet-2684	10	4	no	no	ADV
admet-2684	10	5	in	in	ADV
admet-2684	10	6	vitro	vitro	X
admet-2684	10	7	cytotoxicity	cytotoxicity	NOUN
admet-2684	10	8	up	up	ADP
admet-2684	10	9	to	to	ADP
admet-2684	10	10	a	a	DET
admet-2684	10	11	concentration	concentration	NOUN
admet-2684	10	12	of	of	ADP
admet-2684	10	13	30	30	NUM
admet-2684	10	14	μm	μm	NOUN
admet-2684	10	15	.	.	PUNCT
admet-2684	11	1	conclusion	conclusion	NOUN
admet-2684	11	2	:	:	PUNCT
admet-2684	11	3	from	from	ADP
admet-2684	11	4	the	the	DET
admet-2684	11	5	set	set	NOUN
admet-2684	11	6	of	of	ADP
admet-2684	11	7	tested	test	VERB
admet-2684	11	8	mono-	mono-	NUM
admet-2684	11	9	,	,	PUNCT
admet-2684	11	10	diand	diand	NOUN
admet-2684	11	11	trisubstituted	trisubstitute	VERB
admet-2684	11	12	derivatives	derivative	NOUN
admet-2684	11	13	,	,	PUNCT
admet-2684	11	14	it	it	PRON
admet-2684	11	15	is	be	AUX
admet-2684	11	16	evident	evident	ADJ
admet-2684	11	17	that	that	SCONJ
admet-2684	11	18	the	the	DET
admet-2684	11	19	position	position	NOUN
admet-2684	11	20	of	of	ADP
admet-2684	11	21	chlorine	chlorine	NOUN
admet-2684	11	22	atoms	atom	NOUN
admet-2684	11	23	is	be	AUX
admet-2684	11	24	decisive	decisive	ADJ
admet-2684	11	25	for	for	ADP
admet-2684	11	26	significant	significant	ADJ
admet-2684	11	27	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	11	28	activity	activity	NOUN
admet-2684	11	29	.	.	PUNCT
admet-2684	12	1	inhibition	inhibition	NOUN
admet-2684	12	2	of	of	ADP
admet-2684	12	3	energy	energy	NOUN
admet-2684	12	4	metabolism	metabolism	NOUN
admet-2684	12	5	does	do	AUX
admet-2684	12	6	not	not	PART
admet-2684	12	7	appear	appear	VERB
admet-2684	12	8	to	to	PART
admet-2684	12	9	be	be	AUX
admet-2684	12	10	one	one	NUM
admet-2684	12	11	of	of	ADP
admet-2684	12	12	the	the	DET
admet-2684	12	13	main	main	ADJ
admet-2684	12	14	mechanisms	mechanism	NOUN
admet-2684	12	15	of	of	ADP
admet-2684	12	16	action	action	NOUN
admet-2684	12	17	of	of	ADP
admet-2684	12	18	compound	compound	NOUN
admet-2684	12	19	10	10	NUM
admet-2684	12	20	;	;	PUNCT
admet-2684	12	21	on	on	ADP
admet-2684	12	22	the	the	DET
admet-2684	12	23	contrary	contrary	NOUN
admet-2684	12	24	,	,	PUNCT
admet-2684	12	25	the	the	DET
admet-2684	12	26	antibacterial	antibacterial	ADJ
admet-2684	12	27	effect	effect	NOUN
admet-2684	12	28	may	may	AUX
admet-2684	12	29	likely	likely	ADV
admet-2684	12	30	be	be	AUX
admet-2684	12	31	contributed	contribute	VERB
admet-2684	12	32	by	by	ADP
admet-2684	12	33	downregulation	downregulation	NOUN
admet-2684	12	34	of	of	ADP
admet-2684	12	35	proteins	protein	NOUN
admet-2684	12	36	(	(	PUNCT
admet-2684	12	37	especially	especially	ADV
admet-2684	12	38	atpdependent	atpdependent	ADJ
admet-2684	12	39	protease	protease	NOUN
admet-2684	12	40	atpase	atpase	PROPN
admet-2684	12	41	subunit	subunit	NOUN
admet-2684	12	42	hslu	hslu	PROPN
admet-2684	12	43	)	)	PUNCT
admet-2684	12	44	involved	involve	VERB
admet-2684	12	45	in	in	ADP
admet-2684	12	46	processes	process	NOUN
admet-2684	12	47	essential	essential	ADJ
admet-2684	12	48	for	for	ADP
admet-2684	12	49	bacterial	bacterial	ADJ
admet-2684	12	50	survival	survival	NOUN
admet-2684	12	51	and	and	CCONJ
admet-2684	12	52	growth	growth	NOUN
admet-2684	12	53	,	,	PUNCT
admet-2684	12	54	such	such	ADJ
admet-2684	12	55	as	as	ADP
admet-2684	12	56	protein	protein	NOUN
admet-2684	12	57	,	,	PUNCT
admet-2684	12	58	nucleotide	nucleotide	NOUN
admet-2684	12	59	/	/	SYM
admet-2684	12	60	nucleic	nucleic	ADJ
admet-2684	12	61	acid	acid	NOUN
admet-2684	12	62	synthesis	synthesis	NOUN
admet-2684	12	63	and	and	CCONJ
admet-2684	12	64	efficient	efficient	ADJ
admet-2684	12	65	protein	protein	NOUN
admet-2684	12	66	repair	repair	NOUN
admet-2684	12	67	/	/	SYM
admet-2684	12	68	degradation	degradation	NOUN
admet-2684	12	69	.	.	PUNCT
admet-2684	13	1	©	©	PROPN
admet-2684	13	2	2025	2025	NUM
admet-2684	13	3	by	by	ADP
admet-2684	13	4	the	the	DET
admet-2684	13	5	authors	author	NOUN
admet-2684	13	6	.	.	PUNCT
admet-2684	14	1	this	this	DET
admet-2684	14	2	article	article	NOUN
admet-2684	14	3	is	be	AUX
admet-2684	14	4	an	an	DET
admet-2684	14	5	open	open	ADJ
admet-2684	14	6	-	-	PUNCT
admet-2684	14	7	access	access	NOUN
admet-2684	14	8	article	article	NOUN
admet-2684	14	9	distributed	distribute	VERB
admet-2684	14	10	under	under	ADP
admet-2684	14	11	the	the	DET
admet-2684	14	12	terms	term	NOUN
admet-2684	14	13	and	and	CCONJ
admet-2684	14	14	conditions	condition	NOUN
admet-2684	14	15	of	of	ADP
admet-2684	14	16	the	the	DET
admet-2684	14	17	creative	creative	ADJ
admet-2684	14	18	commons	common	NOUN
admet-2684	14	19	attribution	attribution	NOUN
admet-2684	14	20	license	license	NOUN
admet-2684	14	21	(	(	PUNCT
admet-2684	14	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2684	14	23	)	)	PUNCT
admet-2684	14	24	.	.	PUNCT
admet-2684	15	1	keywords	keyword	VERB
admet-2684	15	2	lipophilicity	lipophilicity	NOUN
admet-2684	15	3	;	;	PUNCT
admet-2684	15	4	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	15	5	activity	activity	NOUN
admet-2684	15	6	;	;	PUNCT
admet-2684	15	7	cytotoxicity	cytotoxicity	NOUN
admet-2684	15	8	;	;	PUNCT
admet-2684	15	9	mtt	mtt	NOUN
admet-2684	15	10	assay	assay	VERB
admet-2684	15	11	;	;	PUNCT
admet-2684	15	12	chemoproteomic	chemoproteomic	ADJ
admet-2684	15	13	analysis	analysis	NOUN
admet-2684	15	14	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	PRON
admet-2684	15	15	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	PROPN
admet-2684	15	16	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-2684	15	17	mailto:kauerovat@pharm.muni.cz	mailto:kauerovat@pharm.muni.cz	PROPN
admet-2684	15	18	mailto:josef.jampilek@gmail.com	mailto:josef.jampilek@gmail.com	PROPN
admet-2684	15	19	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2684	15	20	l.	l.	PROPN
admet-2684	15	21	vrablova	vrablova	PROPN
admet-2684	16	1	et	et	PROPN
admet-2684	16	2	al	al	PROPN
admet-2684	16	3	.	.	PROPN
admet-2684	16	4	admet	admet	PROPN
admet-2684	16	5	&	&	CCONJ
admet-2684	16	6	dmpk	dmpk	PROPN
admet-2684	16	7	13(2	13(2	PROPN
admet-2684	16	8	)	)	PUNCT
admet-2684	16	9	(	(	PUNCT
admet-2684	16	10	2025	2025	NUM
admet-2684	16	11	)	)	PUNCT
admet-2684	16	12	2684	2684	NUM
admet-2684	16	13	2	2	NUM
admet-2684	16	14	introduction	introduction	NOUN
admet-2684	16	15	antimicrobial	antimicrobial	ADJ
admet-2684	16	16	resistance	resistance	NOUN
admet-2684	16	17	(	(	PUNCT
admet-2684	16	18	amr	amr	NOUN
admet-2684	16	19	)	)	PUNCT
admet-2684	16	20	is	be	AUX
admet-2684	16	21	a	a	DET
admet-2684	16	22	major	major	ADJ
admet-2684	16	23	global	global	ADJ
admet-2684	16	24	health	health	NOUN
admet-2684	16	25	challenge	challenge	NOUN
admet-2684	16	26	of	of	ADP
admet-2684	16	27	the	the	DET
admet-2684	16	28	21st	21st	ADJ
admet-2684	16	29	century	century	NOUN
admet-2684	16	30	.	.	PUNCT
admet-2684	17	1	dangerous	dangerous	ADJ
admet-2684	17	2	drugresistant	drugresistant	NOUN
admet-2684	17	3	bacteria	bacteria	NOUN
admet-2684	17	4	include	include	VERB
admet-2684	17	5	third	third	ADJ
admet-2684	17	6	-	-	PUNCT
admet-2684	17	7	generation	generation	NOUN
admet-2684	17	8	cephalosporin	cephalosporin	NOUN
admet-2684	17	9	-	-	PUNCT
admet-2684	17	10	resistant	resistant	ADJ
admet-2684	17	11	escherichia	escherichia	NOUN
admet-2684	17	12	coli	coli	NOUN
admet-2684	17	13	and	and	CCONJ
admet-2684	17	14	methicillin	methicillin	NOUN
admet-2684	17	15	-	-	PUNCT
admet-2684	17	16	resistant	resistant	ADJ
admet-2684	17	17	staphylococcus	staphylococcus	NOUN
admet-2684	17	18	aureus	aureus	NOUN
admet-2684	17	19	,	,	PUNCT
admet-2684	17	20	as	as	ADV
admet-2684	17	21	well	well	ADV
admet-2684	17	22	as	as	ADP
admet-2684	17	23	klebsiella	klebsiella	NOUN
admet-2684	17	24	pneumoniae	pneumoniae	NOUN
admet-2684	17	25	,	,	PUNCT
admet-2684	17	26	pseudomonas	pseudomona	NOUN
admet-2684	17	27	aeruginosa	aeruginosa	NOUN
admet-2684	17	28	,	,	PUNCT
admet-2684	17	29	and	and	CCONJ
admet-2684	17	30	vancomycinresistant	vancomycinresistant	ADJ
admet-2684	17	31	enterococcus	enterococcus	NOUN
admet-2684	17	32	faecalis	faecalis	NOUN
admet-2684	17	33	/	/	SYM
admet-2684	17	34	enterococcus	enterococcus	NOUN
admet-2684	17	35	faecium	faecium	NOUN
admet-2684	18	1	[	[	X
admet-2684	18	2	1	1	NUM
admet-2684	18	3	-	-	SYM
admet-2684	18	4	5	5	NUM
admet-2684	18	5	]	]	PUNCT
admet-2684	18	6	.	.	PUNCT
admet-2684	19	1	studies	study	NOUN
admet-2684	19	2	published	publish	VERB
admet-2684	19	3	in	in	ADP
admet-2684	19	4	the	the	DET
admet-2684	19	5	lancet	lancet	NOUN
admet-2684	19	6	highlight	highlight	VERB
admet-2684	19	7	a	a	DET
admet-2684	19	8	worrying	worrying	ADJ
admet-2684	19	9	trend	trend	NOUN
admet-2684	19	10	in	in	ADP
admet-2684	19	11	the	the	DET
admet-2684	19	12	burden	burden	NOUN
admet-2684	19	13	of	of	ADP
admet-2684	19	14	amr	amr	NOUN
admet-2684	19	15	among	among	ADP
admet-2684	19	16	people	people	NOUN
admet-2684	19	17	over	over	ADP
admet-2684	19	18	70	70	NUM
admet-2684	19	19	years	year	NOUN
admet-2684	19	20	of	of	ADP
admet-2684	19	21	age	age	NOUN
admet-2684	19	22	,	,	PUNCT
admet-2684	19	23	which	which	PRON
admet-2684	19	24	is	be	AUX
admet-2684	19	25	critical	critical	ADJ
admet-2684	19	26	given	give	VERB
admet-2684	19	27	the	the	DET
admet-2684	19	28	rapidly	rapidly	ADV
admet-2684	19	29	ageing	age	VERB
admet-2684	19	30	‘	'	PUNCT
admet-2684	19	31	western	western	ADJ
admet-2684	19	32	’	'	PUNCT
admet-2684	19	33	global	global	ADJ
admet-2684	19	34	community	community	NOUN
admet-2684	19	35	.	.	PUNCT
admet-2684	20	1	given	give	VERB
admet-2684	20	2	the	the	DET
admet-2684	20	3	high	high	ADJ
admet-2684	20	4	variability	variability	NOUN
admet-2684	20	5	in	in	ADP
admet-2684	20	6	the	the	DET
admet-2684	20	7	burden	burden	NOUN
admet-2684	20	8	of	of	ADP
admet-2684	20	9	amr	amr	NOUN
admet-2684	20	10	by	by	ADP
admet-2684	20	11	location	location	NOUN
admet-2684	20	12	and	and	CCONJ
admet-2684	20	13	age	age	NOUN
admet-2684	20	14	,	,	PUNCT
admet-2684	20	15	it	it	PRON
admet-2684	20	16	is	be	AUX
admet-2684	20	17	important	important	ADJ
admet-2684	20	18	that	that	SCONJ
admet-2684	20	19	interventions	intervention	NOUN
admet-2684	20	20	to	to	PART
admet-2684	20	21	prevent	prevent	VERB
admet-2684	20	22	/	/	SYM
admet-2684	20	23	reduce	reduce	VERB
admet-2684	20	24	amr	amr	NOUN
admet-2684	20	25	,	,	PUNCT
admet-2684	20	26	leading	lead	VERB
admet-2684	20	27	to	to	ADP
admet-2684	20	28	a	a	DET
admet-2684	20	29	reduction	reduction	NOUN
admet-2684	20	30	in	in	ADP
admet-2684	20	31	deaths	death	NOUN
admet-2684	20	32	,	,	PUNCT
admet-2684	20	33	combine	combine	VERB
admet-2684	20	34	infection	infection	NOUN
admet-2684	20	35	prevention	prevention	NOUN
admet-2684	20	36	,	,	PUNCT
admet-2684	20	37	vaccination	vaccination	NOUN
admet-2684	20	38	,	,	PUNCT
admet-2684	20	39	minimization	minimization	NOUN
admet-2684	20	40	of	of	ADP
admet-2684	20	41	inappropriate	inappropriate	ADJ
admet-2684	20	42	antibiotic	antibiotic	ADJ
admet-2684	20	43	use	use	NOUN
admet-2684	20	44	in	in	ADP
admet-2684	20	45	agriculture	agriculture	NOUN
admet-2684	20	46	and	and	CCONJ
admet-2684	20	47	humans	human	NOUN
admet-2684	20	48	,	,	PUNCT
admet-2684	20	49	and	and	CCONJ
admet-2684	20	50	research	research	NOUN
admet-2684	20	51	into	into	ADP
admet-2684	20	52	new	new	ADJ
admet-2684	20	53	antibiotics	antibiotic	NOUN
admet-2684	20	54	[	[	X
admet-2684	20	55	5	5	NUM
admet-2684	20	56	-	-	SYM
admet-2684	20	57	7	7	NUM
admet-2684	20	58	]	]	PUNCT
admet-2684	20	59	.	.	PUNCT
admet-2684	21	1	there	there	PRON
admet-2684	21	2	are	be	VERB
admet-2684	21	3	many	many	ADJ
admet-2684	21	4	innovative	innovative	ADJ
admet-2684	21	5	approaches	approach	NOUN
admet-2684	21	6	to	to	ADP
admet-2684	21	7	the	the	DET
admet-2684	21	8	discovery	discovery	NOUN
admet-2684	21	9	,	,	PUNCT
admet-2684	21	10	design	design	NOUN
admet-2684	21	11	and	and	CCONJ
admet-2684	21	12	development	development	NOUN
admet-2684	21	13	of	of	ADP
admet-2684	21	14	new	new	ADJ
admet-2684	21	15	antimicrobial	antimicrobial	ADJ
admet-2684	21	16	drugs	drug	NOUN
admet-2684	21	17	[	[	X
admet-2684	21	18	8	8	NUM
admet-2684	21	19	-	-	SYM
admet-2684	21	20	12	12	NUM
admet-2684	21	21	]	]	PUNCT
admet-2684	21	22	;	;	PUNCT
admet-2684	21	23	one	one	NUM
admet-2684	21	24	of	of	ADP
admet-2684	21	25	them	they	PRON
admet-2684	21	26	is	be	AUX
admet-2684	21	27	the	the	DET
admet-2684	21	28	design	design	NOUN
admet-2684	21	29	of	of	ADP
admet-2684	21	30	multitargeted	multitargeted	ADJ
admet-2684	21	31	agents	agent	NOUN
admet-2684	21	32	,	,	PUNCT
admet-2684	21	33	i.e.	i.e.	X
admet-2684	21	34	compounds	compound	NOUN
admet-2684	21	35	capable	capable	ADJ
admet-2684	21	36	of	of	ADP
admet-2684	21	37	interfering	interfere	VERB
admet-2684	21	38	with	with	ADP
admet-2684	21	39	microorganisms	microorganism	NOUN
admet-2684	21	40	at	at	ADP
admet-2684	21	41	multiple	multiple	ADJ
admet-2684	21	42	sites	site	NOUN
admet-2684	21	43	and	and	CCONJ
admet-2684	21	44	preventing	prevent	VERB
admet-2684	21	45	them	they	PRON
admet-2684	21	46	from	from	ADP
admet-2684	21	47	developing	develop	VERB
admet-2684	21	48	resistance	resistance	NOUN
admet-2684	21	49	through	through	ADP
admet-2684	21	50	multiple	multiple	ADJ
admet-2684	21	51	interventions	intervention	NOUN
admet-2684	21	52	,	,	PUNCT
admet-2684	21	53	whether	whether	SCONJ
admet-2684	21	54	in	in	ADP
admet-2684	21	55	serial	serial	ADJ
admet-2684	21	56	or	or	CCONJ
admet-2684	21	57	parallel	parallel	ADJ
admet-2684	21	58	action	action	NOUN
admet-2684	21	59	on	on	ADP
admet-2684	21	60	metabolic	metabolic	NOUN
admet-2684	21	61	pathways	pathway	NOUN
admet-2684	21	62	,	,	PUNCT
admet-2684	21	63	reproduction	reproduction	NOUN
admet-2684	21	64	or	or	CCONJ
admet-2684	21	65	action	action	NOUN
admet-2684	21	66	on	on	ADP
admet-2684	21	67	membrane	membrane	NOUN
admet-2684	21	68	systems	system	NOUN
admet-2684	21	69	[	[	X
admet-2684	21	70	13	13	NUM
admet-2684	21	71	-	-	SYM
admet-2684	21	72	17	17	NUM
admet-2684	21	73	]	]	PUNCT
admet-2684	21	74	.	.	PUNCT
admet-2684	22	1	salicylamides	salicylamide	NOUN
admet-2684	22	2	are	be	AUX
admet-2684	22	3	a	a	DET
admet-2684	22	4	typical	typical	ADJ
admet-2684	22	5	example	example	NOUN
admet-2684	22	6	of	of	ADP
admet-2684	22	7	such	such	ADJ
admet-2684	22	8	multitarget	multitarget	PROPN
admet-2684	22	9	agents	agent	NOUN
admet-2684	22	10	,	,	PUNCT
admet-2684	22	11	which	which	PRON
admet-2684	22	12	are	be	AUX
admet-2684	22	13	characterized	characterize	VERB
admet-2684	22	14	by	by	ADP
admet-2684	22	15	a	a	DET
admet-2684	22	16	complex	complex	ADJ
admet-2684	22	17	antiinvasive	antiinvasive	ADJ
admet-2684	22	18	effect	effect	NOUN
admet-2684	22	19	against	against	ADP
admet-2684	22	20	parasites	parasite	NOUN
admet-2684	22	21	,	,	PUNCT
admet-2684	22	22	microorganisms	microorganism	NOUN
admet-2684	22	23	and	and	CCONJ
admet-2684	22	24	cancer	cancer	NOUN
admet-2684	22	25	cells	cell	NOUN
admet-2684	22	26	[	[	X
admet-2684	22	27	16,18	16,18	NUM
admet-2684	22	28	-	-	SYM
admet-2684	22	29	20,21	20,21	NUM
admet-2684	22	30	and	and	CCONJ
admet-2684	22	31	refs	ref	NOUN
admet-2684	22	32	.	.	PUNCT
admet-2684	23	1	therein	therein	ADV
admet-2684	23	2	,	,	PUNCT
admet-2684	23	3	22	22	NUM
admet-2684	23	4	-	-	SYM
admet-2684	23	5	26	26	NUM
admet-2684	23	6	]	]	PUNCT
admet-2684	23	7	,	,	PUNCT
admet-2684	23	8	they	they	PRON
admet-2684	23	9	even	even	ADV
admet-2684	23	10	have	have	VERB
admet-2684	23	11	herbicidal	herbicidal	NOUN
admet-2684	23	12	effects	effect	NOUN
admet-2684	23	13	[	[	X
admet-2684	23	14	27,28	27,28	X
admet-2684	23	15	]	]	X
admet-2684	23	16	.	.	PUNCT
admet-2684	24	1	hydroxynaphthalenecarboxanilides	hydroxynaphthalenecarboxanilide	NOUN
admet-2684	24	2	,	,	PUNCT
admet-2684	24	3	cyclic	cyclic	ADJ
admet-2684	24	4	analogues	analogue	NOUN
admet-2684	24	5	of	of	ADP
admet-2684	24	6	the	the	DET
admet-2684	24	7	parent	parent	NOUN
admet-2684	24	8	salicylanilides	salicylanilide	NOUN
admet-2684	24	9	prepared	prepare	VERB
admet-2684	24	10	by	by	ADP
admet-2684	24	11	our	our	PRON
admet-2684	24	12	team	team	NOUN
admet-2684	24	13	,	,	PUNCT
admet-2684	24	14	can	can	AUX
admet-2684	24	15	also	also	ADV
admet-2684	24	16	be	be	AUX
admet-2684	24	17	considered	consider	VERB
admet-2684	24	18	multitarget	multitarget	NOUN
admet-2684	24	19	compounds	compound	NOUN
admet-2684	24	20	.	.	PUNCT
admet-2684	25	1	1	1	NUM
admet-2684	25	2	-	-	NUM
admet-2684	25	3	hydroxynaphthalene	hydroxynaphthalene	ADJ
admet-2684	25	4	-2	-2	NOUN
admet-2684	25	5	-	-	PUNCT
admet-2684	25	6	carboxanilides	carboxanilide	NOUN
admet-2684	25	7	have	have	AUX
admet-2684	25	8	been	be	AUX
admet-2684	25	9	investigated	investigate	VERB
admet-2684	25	10	primarily	primarily	ADV
admet-2684	25	11	as	as	ADP
admet-2684	25	12	potential	potential	ADJ
admet-2684	25	13	anti	anti	ADJ
admet-2684	25	14	-	-	ADJ
admet-2684	25	15	infective	infective	ADJ
admet-2684	25	16	[	[	X
admet-2684	25	17	29	29	NUM
admet-2684	25	18	-	-	SYM
admet-2684	25	19	31	31	NUM
admet-2684	25	20	]	]	PUNCT
admet-2684	25	21	and	and	CCONJ
admet-2684	25	22	anti	anti	ADJ
admet-2684	25	23	-	-	ADJ
admet-2684	25	24	cancer	cancer	ADJ
admet-2684	26	1	[	[	X
admet-2684	26	2	32,33	32,33	NUM
admet-2684	26	3	]	]	X
admet-2684	26	4	agents	agent	NOUN
admet-2684	26	5	.	.	PUNCT
admet-2684	27	1	although	although	SCONJ
admet-2684	27	2	it	it	PRON
admet-2684	27	3	is	be	AUX
admet-2684	27	4	believed	believe	VERB
admet-2684	27	5	that	that	SCONJ
admet-2684	27	6	these	these	DET
admet-2684	27	7	molecules	molecule	NOUN
admet-2684	27	8	may	may	AUX
admet-2684	27	9	act	act	VERB
admet-2684	27	10	as	as	ADP
admet-2684	27	11	proton	proton	NOUN
admet-2684	27	12	shuttle	shuttle	NOUN
admet-2684	27	13	inhibitors	inhibitor	NOUN
admet-2684	27	14	,	,	PUNCT
admet-2684	27	15	i.e.	i.e.	X
admet-2684	27	16	these	these	DET
admet-2684	27	17	compounds	compound	NOUN
admet-2684	27	18	may	may	AUX
admet-2684	27	19	destroy	destroy	VERB
admet-2684	27	20	the	the	DET
admet-2684	27	21	cellular	cellular	ADJ
admet-2684	27	22	proton	proton	NOUN
admet-2684	27	23	gradient	gradient	NOUN
admet-2684	28	1	[	[	X
admet-2684	28	2	34,35	34,35	NOUN
admet-2684	28	3	]	]	X
admet-2684	28	4	,	,	PUNCT
admet-2684	28	5	salicylamides	salicylamide	NOUN
admet-2684	28	6	'	'	PART
admet-2684	28	7	main	main	ADJ
admet-2684	28	8	mechanisms	mechanism	NOUN
admet-2684	28	9	of	of	ADP
admet-2684	28	10	action	action	NOUN
admet-2684	28	11	appear	appear	VERB
admet-2684	28	12	to	to	PART
admet-2684	28	13	be	be	AUX
admet-2684	28	14	inhibition	inhibition	NOUN
admet-2684	28	15	of	of	ADP
admet-2684	28	16	many	many	ADJ
admet-2684	28	17	enzymes	enzyme	NOUN
admet-2684	28	18	[	[	PUNCT
admet-2684	28	19	19	19	NUM
admet-2684	28	20	-	-	SYM
admet-2684	28	21	27	27	NUM
admet-2684	28	22	,	,	PUNCT
admet-2684	28	23	28	28	NUM
admet-2684	28	24	and	and	CCONJ
admet-2684	28	25	refs	ref	NOUN
admet-2684	28	26	.	.	PUNCT
admet-2684	29	1	therein	therein	ADV
admet-2684	29	2	]	]	PUNCT
admet-2684	29	3	,	,	PUNCT
admet-2684	29	4	including	include	VERB
admet-2684	29	5	inhibition	inhibition	NOUN
admet-2684	29	6	of	of	ADP
admet-2684	29	7	the	the	DET
admet-2684	29	8	twocomponent	twocomponent	NOUN
admet-2684	29	9	regulatory	regulatory	ADJ
admet-2684	29	10	system	system	NOUN
admet-2684	29	11	of	of	ADP
admet-2684	29	12	bacteria	bacteria	NOUN
admet-2684	30	1	[	[	X
admet-2684	30	2	36,37	36,37	X
admet-2684	30	3	]	]	X
admet-2684	30	4	.	.	PUNCT
admet-2684	31	1	a	a	DET
admet-2684	31	2	disadvantage	disadvantage	NOUN
admet-2684	31	3	of	of	ADP
admet-2684	31	4	multitargeted	multitargete	VERB
admet-2684	31	5	agents	agent	NOUN
admet-2684	31	6	is	be	AUX
admet-2684	31	7	that	that	SCONJ
admet-2684	31	8	it	it	PRON
admet-2684	31	9	is	be	AUX
admet-2684	31	10	difficult	difficult	ADJ
admet-2684	31	11	to	to	PART
admet-2684	31	12	precisely	precisely	ADV
admet-2684	31	13	determine	determine	VERB
admet-2684	31	14	/	/	SYM
admet-2684	31	15	identify	identify	VERB
admet-2684	31	16	their	their	PRON
admet-2684	31	17	mechanisms	mechanism	NOUN
admet-2684	31	18	of	of	ADP
admet-2684	31	19	action	action	NOUN
admet-2684	31	20	.	.	PUNCT
admet-2684	32	1	one	one	NUM
admet-2684	32	2	option	option	NOUN
admet-2684	32	3	that	that	PRON
admet-2684	32	4	could	could	AUX
admet-2684	32	5	help	help	VERB
admet-2684	32	6	uncover	uncover	VERB
admet-2684	32	7	the	the	DET
admet-2684	32	8	mechanism	mechanism	NOUN
admet-2684	32	9	of	of	ADP
admet-2684	32	10	action	action	NOUN
admet-2684	32	11	of	of	ADP
admet-2684	32	12	these	these	DET
admet-2684	32	13	compounds	compound	NOUN
admet-2684	32	14	is	be	AUX
admet-2684	32	15	the	the	DET
admet-2684	32	16	use	use	NOUN
admet-2684	32	17	of	of	ADP
admet-2684	32	18	chemoproteomics	chemoproteomic	NOUN
admet-2684	32	19	,	,	PUNCT
admet-2684	32	20	which	which	PRON
admet-2684	32	21	has	have	AUX
admet-2684	32	22	become	become	VERB
admet-2684	32	23	a	a	DET
admet-2684	32	24	useful	useful	ADJ
admet-2684	32	25	tool	tool	NOUN
admet-2684	32	26	in	in	ADP
admet-2684	32	27	modern	modern	ADJ
admet-2684	32	28	drug	drug	NOUN
admet-2684	32	29	discovery	discovery	NOUN
admet-2684	32	30	and	and	CCONJ
admet-2684	32	31	preclinical	preclinical	ADJ
admet-2684	32	32	research	research	NOUN
admet-2684	32	33	[	[	X
admet-2684	32	34	38	38	NUM
admet-2684	32	35	]	]	PUNCT
admet-2684	32	36	,	,	PUNCT
admet-2684	32	37	providing	provide	VERB
admet-2684	32	38	critical	critical	ADJ
admet-2684	32	39	insight	insight	NOUN
admet-2684	32	40	into	into	ADP
admet-2684	32	41	the	the	DET
admet-2684	32	42	interactions	interaction	NOUN
admet-2684	32	43	between	between	ADP
admet-2684	32	44	bioactive	bioactive	ADJ
admet-2684	32	45	compounds	compound	NOUN
admet-2684	32	46	and	and	CCONJ
admet-2684	32	47	protein	protein	NOUN
admet-2684	32	48	targets	target	NOUN
admet-2684	32	49	within	within	ADP
admet-2684	32	50	complex	complex	ADJ
admet-2684	32	51	biological	biological	ADJ
admet-2684	32	52	systems	system	NOUN
admet-2684	32	53	[	[	X
admet-2684	32	54	39	39	NUM
admet-2684	32	55	]	]	PUNCT
admet-2684	32	56	.	.	PUNCT
admet-2684	33	1	by	by	ADP
admet-2684	33	2	identifying	identify	VERB
admet-2684	33	3	the	the	DET
admet-2684	33	4	proteins	protein	NOUN
admet-2684	33	5	to	to	PART
admet-2684	33	6	which	which	PRON
admet-2684	33	7	small	small	ADJ
admet-2684	33	8	molecules	molecule	NOUN
admet-2684	33	9	bind	bind	VERB
admet-2684	33	10	,	,	PUNCT
admet-2684	33	11	chemoproteomics	chemoproteomic	NOUN
admet-2684	33	12	allows	allow	VERB
admet-2684	33	13	for	for	ADP
admet-2684	33	14	mapping	map	VERB
admet-2684	33	15	the	the	DET
admet-2684	33	16	mechanisms	mechanism	NOUN
admet-2684	33	17	of	of	ADP
admet-2684	33	18	action	action	NOUN
admet-2684	33	19	of	of	ADP
admet-2684	33	20	potential	potential	ADJ
admet-2684	33	21	therapeutics	therapeutic	NOUN
admet-2684	33	22	as	as	ADV
admet-2684	33	23	well	well	ADV
admet-2684	33	24	as	as	ADP
admet-2684	33	25	identifying	identify	VERB
admet-2684	33	26	unintended	unintended	ADJ
admet-2684	33	27	off	off	ADP
admet-2684	33	28	-	-	PUNCT
admet-2684	33	29	target	target	NOUN
admet-2684	33	30	effects	effect	NOUN
admet-2684	33	31	that	that	PRON
admet-2684	33	32	could	could	AUX
admet-2684	33	33	lead	lead	VERB
admet-2684	33	34	to	to	ADP
admet-2684	33	35	toxicity	toxicity	NOUN
admet-2684	33	36	[	[	X
admet-2684	33	37	40	40	NUM
admet-2684	33	38	]	]	PUNCT
admet-2684	33	39	.	.	PUNCT
admet-2684	34	1	the	the	DET
admet-2684	34	2	primary	primary	ADJ
admet-2684	34	3	goal	goal	NOUN
admet-2684	34	4	of	of	ADP
admet-2684	34	5	chemoproteomics	chemoproteomic	NOUN
admet-2684	34	6	is	be	AUX
admet-2684	34	7	to	to	PART
admet-2684	34	8	investigate	investigate	VERB
admet-2684	34	9	how	how	SCONJ
admet-2684	34	10	small	small	ADJ
admet-2684	34	11	bioactive	bioactive	ADJ
admet-2684	34	12	molecules	molecule	NOUN
admet-2684	34	13	interact	interact	VERB
admet-2684	34	14	with	with	ADP
admet-2684	34	15	proteins	protein	NOUN
admet-2684	34	16	in	in	ADP
admet-2684	34	17	their	their	PRON
admet-2684	34	18	native	native	ADJ
admet-2684	34	19	cellular	cellular	ADJ
admet-2684	34	20	environment	environment	NOUN
admet-2684	34	21	[	[	X
admet-2684	34	22	41	41	NUM
admet-2684	34	23	]	]	PUNCT
admet-2684	34	24	.	.	PUNCT
admet-2684	35	1	this	this	PRON
admet-2684	35	2	is	be	AUX
admet-2684	35	3	typically	typically	ADV
admet-2684	35	4	achieved	achieve	VERB
admet-2684	35	5	using	use	VERB
admet-2684	35	6	activity	activity	NOUN
admet-2684	35	7	-	-	PUNCT
admet-2684	35	8	based	base	VERB
admet-2684	35	9	protein	protein	NOUN
admet-2684	35	10	profiling	profiling	NOUN
admet-2684	35	11	(	(	PUNCT
admet-2684	35	12	abpp	abpp	PROPN
admet-2684	35	13	)	)	PUNCT
admet-2684	35	14	,	,	PUNCT
admet-2684	35	15	a	a	DET
admet-2684	35	16	powerful	powerful	ADJ
admet-2684	35	17	chemoproteomics	chemoproteomic	NOUN
admet-2684	35	18	technique	technique	NOUN
admet-2684	35	19	that	that	PRON
admet-2684	35	20	uses	use	VERB
admet-2684	35	21	small	small	ADJ
admet-2684	35	22	molecular	molecular	ADJ
admet-2684	35	23	probes	probe	NOUN
admet-2684	35	24	to	to	PART
admet-2684	35	25	label	label	VERB
admet-2684	35	26	and	and	CCONJ
admet-2684	35	27	capture	capture	VERB
admet-2684	35	28	proteins	protein	NOUN
admet-2684	35	29	in	in	ADP
admet-2684	35	30	a	a	DET
admet-2684	35	31	functional	functional	ADJ
admet-2684	35	32	state	state	NOUN
admet-2684	36	1	[	[	X
admet-2684	36	2	42	42	NUM
admet-2684	36	3	]	]	PUNCT
admet-2684	36	4	.	.	PUNCT
admet-2684	37	1	the	the	DET
admet-2684	37	2	resulting	result	VERB
admet-2684	37	3	labeled	label	VERB
admet-2684	37	4	proteins	protein	NOUN
admet-2684	37	5	can	can	AUX
admet-2684	37	6	then	then	ADV
admet-2684	37	7	be	be	AUX
admet-2684	37	8	analyzed	analyze	VERB
admet-2684	37	9	using	use	VERB
admet-2684	37	10	liquid	liquid	ADJ
admet-2684	37	11	chromatography	chromatography	NOUN
admet-2684	37	12	-	-	PUNCT
admet-2684	37	13	tandem	tandem	NOUN
admet-2684	37	14	mass	mass	ADJ
admet-2684	37	15	spectrometry	spectrometry	NOUN
admet-2684	37	16	(	(	PUNCT
admet-2684	37	17	lc	lc	PROPN
admet-2684	37	18	-	-	PUNCT
admet-2684	37	19	ms	ms	PROPN
admet-2684	37	20	/	/	SYM
admet-2684	37	21	ms	ms	PROPN
admet-2684	37	22	)	)	PUNCT
admet-2684	37	23	,	,	PUNCT
admet-2684	37	24	which	which	PRON
admet-2684	37	25	provides	provide	VERB
admet-2684	37	26	a	a	DET
admet-2684	37	27	detailed	detailed	ADJ
admet-2684	37	28	proteomic	proteomic	ADJ
admet-2684	37	29	profile	profile	NOUN
admet-2684	37	30	of	of	ADP
admet-2684	37	31	the	the	DET
admet-2684	37	32	cellular	cellular	ADJ
admet-2684	37	33	response	response	NOUN
admet-2684	37	34	to	to	ADP
admet-2684	37	35	the	the	DET
admet-2684	37	36	compound	compound	NOUN
admet-2684	38	1	[	[	X
admet-2684	38	2	38,43	38,43	NOUN
admet-2684	38	3	]	]	PUNCT
admet-2684	38	4	.	.	PUNCT
admet-2684	39	1	given	give	VERB
admet-2684	39	2	the	the	DET
admet-2684	39	3	demonstrated	demonstrate	VERB
admet-2684	39	4	improvement	improvement	NOUN
admet-2684	39	5	of	of	ADP
admet-2684	39	6	anti	anti	ADJ
admet-2684	39	7	-	-	ADJ
admet-2684	39	8	infective	infective	ADJ
admet-2684	39	9	properties	property	NOUN
admet-2684	39	10	through	through	ADP
admet-2684	39	11	chlorination	chlorination	NOUN
admet-2684	39	12	[	[	X
admet-2684	39	13	22,44	22,44	NUM
admet-2684	39	14	-	-	SYM
admet-2684	39	15	50	50	NUM
admet-2684	39	16	]	]	PUNCT
admet-2684	39	17	,	,	PUNCT
admet-2684	39	18	this	this	DET
admet-2684	39	19	study	study	NOUN
admet-2684	39	20	aims	aim	VERB
admet-2684	39	21	to	to	PART
admet-2684	39	22	elucidate	elucidate	VERB
admet-2684	39	23	the	the	DET
admet-2684	39	24	previously	previously	ADV
admet-2684	39	25	unreported	unreported	ADJ
admet-2684	39	26	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	39	27	activity	activity	NOUN
admet-2684	39	28	of	of	ADP
admet-2684	39	29	chlorinated	chlorinate	VERB
admet-2684	39	30	1	1	NUM
admet-2684	39	31	-	-	PUNCT
admet-2684	39	32	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	39	33	-	-	PUNCT
admet-2684	39	34	carboxanilides	carboxanilide	NOUN
admet-2684	39	35	.	.	PUNCT
admet-2684	40	1	specifically	specifically	ADV
admet-2684	40	2	,	,	PUNCT
admet-2684	40	3	the	the	DET
admet-2684	40	4	collection	collection	NOUN
admet-2684	40	5	of	of	ADP
admet-2684	40	6	susceptible	susceptible	ADJ
admet-2684	40	7	s.	s.	PROPN
admet-2684	40	8	aureus	aureus	PROPN
admet-2684	40	9	and	and	CCONJ
admet-2684	40	10	its	its	PRON
admet-2684	40	11	mrsa	mrsa	NOUN
admet-2684	40	12	isolates	isolate	NOUN
admet-2684	40	13	were	be	AUX
admet-2684	40	14	deliberately	deliberately	ADV
admet-2684	40	15	selected	select	VERB
admet-2684	40	16	as	as	SCONJ
admet-2684	40	17	they	they	PRON
admet-2684	40	18	represent	represent	VERB
admet-2684	40	19	the	the	DET
admet-2684	40	20	most	most	ADV
admet-2684	40	21	prevalent	prevalent	ADJ
admet-2684	40	22	and	and	CCONJ
admet-2684	40	23	clinically	clinically	ADV
admet-2684	40	24	significant	significant	ADJ
admet-2684	40	25	gram	gram	NOUN
admet-2684	40	26	-	-	PUNCT
admet-2684	40	27	positive	positive	ADJ
admet-2684	40	28	pathogens	pathogen	NOUN
admet-2684	40	29	responsible	responsible	ADJ
admet-2684	40	30	for	for	ADP
admet-2684	40	31	a	a	DET
admet-2684	40	32	spectrum	spectrum	NOUN
admet-2684	40	33	of	of	ADP
admet-2684	40	34	infections	infection	NOUN
admet-2684	40	35	ranging	range	VERB
admet-2684	40	36	from	from	ADP
admet-2684	40	37	superficial	superficial	ADJ
admet-2684	40	38	skin	skin	NOUN
admet-2684	40	39	lesions	lesion	NOUN
admet-2684	40	40	to	to	ADP
admet-2684	40	41	severe	severe	ADJ
admet-2684	40	42	conditions	condition	NOUN
admet-2684	40	43	like	like	ADP
admet-2684	40	44	pneumonia	pneumonia	NOUN
admet-2684	40	45	and	and	CCONJ
admet-2684	40	46	sepsis	sepsis	NOUN
admet-2684	41	1	[	[	X
admet-2684	41	2	51	51	NUM
admet-2684	41	3	]	]	PUNCT
admet-2684	41	4	.	.	PUNCT
admet-2684	42	1	to	to	PART
admet-2684	42	2	investigate	investigate	VERB
admet-2684	42	3	the	the	DET
admet-2684	42	4	mechanism	mechanism	NOUN
admet-2684	42	5	of	of	ADP
admet-2684	42	6	action	action	NOUN
admet-2684	42	7	,	,	PUNCT
admet-2684	42	8	not	not	PART
admet-2684	42	9	only	only	ADV
admet-2684	42	10	the	the	DET
admet-2684	42	11	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	42	12	efficacy	efficacy	NOUN
admet-2684	42	13	was	be	AUX
admet-2684	42	14	evaluated	evaluate	VERB
admet-2684	42	15	,	,	PUNCT
admet-2684	42	16	but	but	CCONJ
admet-2684	42	17	also	also	ADV
admet-2684	42	18	the	the	DET
admet-2684	42	19	impact	impact	NOUN
admet-2684	42	20	of	of	ADP
admet-2684	42	21	active	active	ADJ
admet-2684	42	22	derivatives	derivative	NOUN
admet-2684	42	23	on	on	ADP
admet-2684	42	24	bacterial	bacterial	ADJ
admet-2684	42	25	respiration	respiration	NOUN
admet-2684	42	26	(	(	PUNCT
admet-2684	42	27	energy	energy	NOUN
admet-2684	42	28	metabolism	metabolism	NOUN
admet-2684	42	29	)	)	PUNCT
admet-2684	42	30	and	and	CCONJ
admet-2684	42	31	intracellular	intracellular	ADJ
admet-2684	42	32	admet	admet	NOUN
admet-2684	42	33	&	&	CCONJ
admet-2684	42	34	dmpk	dmpk	PROPN
admet-2684	42	35	13(2	13(2	PROPN
admet-2684	42	36	)	)	PUNCT
admet-2684	42	37	(	(	PUNCT
admet-2684	42	38	2025	2025	NUM
admet-2684	42	39	)	)	PUNCT
admet-2684	42	40	2684	2684	NUM
admet-2684	42	41	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	42	42	effect	effect	NOUN
admet-2684	42	43	of	of	ADP
admet-2684	42	44	chlorinated	chlorinate	VERB
admet-2684	42	45	1	1	NUM
admet-2684	42	46	-	-	PUNCT
admet-2684	42	47	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	42	48	-	-	PUNCT
admet-2684	42	49	carboxanilides	carboxanilide	NOUN
admet-2684	42	50	doi	doi	NOUN
admet-2684	42	51	:	:	PUNCT
admet-2684	42	52	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	42	53	3	3	NUM
admet-2684	42	54	processes	process	NOUN
admet-2684	42	55	.	.	PUNCT
admet-2684	43	1	the	the	DET
admet-2684	43	2	application	application	NOUN
admet-2684	43	3	of	of	ADP
admet-2684	43	4	a	a	DET
admet-2684	43	5	contemporary	contemporary	ADJ
admet-2684	43	6	chemoproteomic	chemoproteomic	ADJ
admet-2684	43	7	approach	approach	NOUN
admet-2684	43	8	,	,	PUNCT
admet-2684	43	9	including	include	VERB
admet-2684	43	10	the	the	DET
admet-2684	43	11	comparative	comparative	ADJ
admet-2684	43	12	abpp	abpp	ADJ
admet-2684	43	13	technique	technique	NOUN
admet-2684	43	14	,	,	PUNCT
admet-2684	43	15	supported	support	VERB
admet-2684	43	16	the	the	DET
admet-2684	43	17	effort	effort	NOUN
admet-2684	43	18	to	to	PART
admet-2684	43	19	determine	determine	VERB
admet-2684	43	20	the	the	DET
admet-2684	43	21	protein	protein	NOUN
admet-2684	43	22	profile	profile	NOUN
admet-2684	43	23	alterations	alteration	NOUN
admet-2684	43	24	induced	induce	VERB
admet-2684	43	25	in	in	ADP
admet-2684	43	26	both	both	DET
admet-2684	43	27	reference	reference	NOUN
admet-2684	43	28	s.	s.	PROPN
admet-2684	43	29	aureus	aureus	PROPN
admet-2684	43	30	and	and	CCONJ
admet-2684	43	31	mrsa	mrsa	NOUN
admet-2684	43	32	strains	strain	VERB
admet-2684	43	33	following	follow	VERB
admet-2684	43	34	treatment	treatment	NOUN
admet-2684	43	35	with	with	ADP
admet-2684	43	36	selected	select	VERB
admet-2684	43	37	ring	ring	NOUN
admet-2684	43	38	-	-	PUNCT
admet-2684	43	39	substituted	substitute	VERB
admet-2684	43	40	1	1	NUM
admet-2684	43	41	-	-	PUNCT
admet-2684	43	42	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	43	43	-	-	PUNCT
admet-2684	43	44	carboxanilides	carboxanilide	NOUN
admet-2684	43	45	.	.	PUNCT
admet-2684	44	1	this	this	DET
admet-2684	44	2	comprehensive	comprehensive	ADJ
admet-2684	44	3	study	study	NOUN
admet-2684	44	4	,	,	PUNCT
admet-2684	44	5	including	include	VERB
admet-2684	44	6	proteomic	proteomic	ADJ
admet-2684	44	7	analysis	analysis	NOUN
admet-2684	44	8	,	,	PUNCT
admet-2684	44	9	is	be	AUX
admet-2684	44	10	expected	expect	VERB
admet-2684	44	11	to	to	PART
admet-2684	44	12	provide	provide	VERB
admet-2684	44	13	valuable	valuable	ADJ
admet-2684	44	14	insights	insight	NOUN
admet-2684	44	15	into	into	ADP
admet-2684	44	16	the	the	DET
admet-2684	44	17	molecular	molecular	ADJ
admet-2684	44	18	mechanisms	mechanism	NOUN
admet-2684	44	19	underlying	underlie	VERB
admet-2684	44	20	the	the	DET
admet-2684	44	21	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	44	22	effects	effect	NOUN
admet-2684	44	23	of	of	ADP
admet-2684	44	24	these	these	DET
admet-2684	44	25	novel	novel	ADJ
admet-2684	44	26	chlorinated	chlorinate	VERB
admet-2684	44	27	compounds	compound	NOUN
admet-2684	44	28	.	.	PUNCT
admet-2684	45	1	experimental	experimental	ADJ
admet-2684	45	2	synthesis	synthesis	NOUN
admet-2684	45	3	the	the	DET
admet-2684	45	4	synthetic	synthetic	ADJ
admet-2684	45	5	pathway	pathway	NOUN
admet-2684	45	6	and	and	CCONJ
admet-2684	45	7	characterization	characterization	NOUN
admet-2684	45	8	of	of	ADP
admet-2684	45	9	compounds	compound	NOUN
admet-2684	45	10	1	1	NUM
admet-2684	45	11	-	-	SYM
admet-2684	45	12	4	4	NUM
admet-2684	45	13	were	be	AUX
admet-2684	45	14	described	describe	VERB
admet-2684	45	15	by	by	ADP
admet-2684	45	16	gonec	gonec	PROPN
admet-2684	45	17	et	et	PROPN
admet-2684	45	18	al	al	PROPN
admet-2684	45	19	.	.	PUNCT
admet-2684	46	1	[	[	X
admet-2684	46	2	29	29	NUM
admet-2684	46	3	]	]	PUNCT
admet-2684	46	4	,	,	PUNCT
admet-2684	46	5	while	while	SCONJ
admet-2684	46	6	compounds	compound	NOUN
admet-2684	46	7	5	5	NUM
admet-2684	46	8	-	-	SYM
admet-2684	46	9	13	13	NUM
admet-2684	46	10	were	be	AUX
admet-2684	46	11	described	describe	VERB
admet-2684	46	12	in	in	ADP
admet-2684	46	13	[	[	X
admet-2684	46	14	52	52	NUM
admet-2684	46	15	]	]	PUNCT
admet-2684	46	16	.	.	PUNCT
admet-2684	47	1	lipophilicity	lipophilicity	NOUN
admet-2684	47	2	determination	determination	NOUN
admet-2684	47	3	by	by	ADP
admet-2684	47	4	hplc	hplc	PROPN
admet-2684	47	5	an	an	DET
admet-2684	47	6	hplc	hplc	NOUN
admet-2684	47	7	system	system	NOUN
admet-2684	47	8	agilent	agilent	PROPN
admet-2684	47	9	1200	1200	NUM
admet-2684	47	10	equipped	equip	VERB
admet-2684	47	11	with	with	ADP
admet-2684	47	12	a	a	DET
admet-2684	47	13	dad	dad	NOUN
admet-2684	47	14	detector	detector	NOUN
admet-2684	47	15	(	(	PUNCT
admet-2684	47	16	agilent	agilent	PROPN
admet-2684	47	17	,	,	PUNCT
admet-2684	47	18	santa	santa	PROPN
admet-2684	47	19	clara	clara	PROPN
admet-2684	47	20	,	,	PUNCT
admet-2684	47	21	ca	ca	PROPN
admet-2684	47	22	,	,	PUNCT
admet-2684	47	23	usa	usa	PROPN
admet-2684	47	24	)	)	PUNCT
admet-2684	47	25	was	be	AUX
admet-2684	47	26	used	use	VERB
admet-2684	47	27	.	.	PUNCT
admet-2684	48	1	a	a	DET
admet-2684	48	2	chromatographic	chromatographic	ADJ
admet-2684	48	3	column	column	NOUN
admet-2684	48	4	symmetry	symmetry	NOUN
admet-2684	48	5	®	®	NOUN
admet-2684	48	6	c18	c18	NOUN
admet-2684	48	7	5	5	NUM
admet-2684	48	8	μm	μm	NOUN
admet-2684	48	9	,	,	PUNCT
admet-2684	48	10	4.6×250	4.6×250	PROPN
admet-2684	48	11	mm	mm	PROPN
admet-2684	48	12	,	,	PUNCT
admet-2684	48	13	part	part	NOUN
admet-2684	48	14	no	no	INTJ
admet-2684	48	15	.	.	PUNCT
admet-2684	48	16	wat054275	wat054275	PROPN
admet-2684	48	17	(	(	PUNCT
admet-2684	48	18	waters	waters	PROPN
admet-2684	48	19	corp	corp	PROPN
admet-2684	48	20	.	.	PROPN
admet-2684	48	21	,	,	PUNCT
admet-2684	48	22	milford	milford	PROPN
admet-2684	48	23	,	,	PUNCT
admet-2684	48	24	ma	ma	PROPN
admet-2684	48	25	,	,	PUNCT
admet-2684	48	26	usa	usa	PROPN
admet-2684	48	27	)	)	PUNCT
admet-2684	48	28	was	be	AUX
admet-2684	48	29	used	use	VERB
admet-2684	48	30	.	.	PUNCT
admet-2684	49	1	the	the	DET
admet-2684	49	2	hplc	hplc	NOUN
admet-2684	49	3	separation	separation	NOUN
admet-2684	49	4	process	process	NOUN
admet-2684	49	5	was	be	AUX
admet-2684	49	6	monitored	monitor	VERB
admet-2684	49	7	and	and	CCONJ
admet-2684	49	8	evaluated	evaluate	VERB
admet-2684	49	9	with	with	ADP
admet-2684	49	10	ezchrom	ezchrom	NOUN
admet-2684	49	11	elite	elite	ADJ
admet-2684	49	12	software	software	NOUN
admet-2684	49	13	ver	ver	NOUN
admet-2684	49	14	.	.	PUNCT
admet-2684	50	1	3.3.2	3.3.2	NUM
admet-2684	50	2	[	[	X
admet-2684	50	3	53	53	NUM
admet-2684	50	4	]	]	PUNCT
admet-2684	50	5	(	(	PUNCT
admet-2684	50	6	agilent	agilent	PROPN
admet-2684	50	7	)	)	PUNCT
admet-2684	50	8	.	.	PUNCT
admet-2684	51	1	isocratic	isocratic	ADJ
admet-2684	51	2	elution	elution	NOUN
admet-2684	51	3	by	by	ADP
admet-2684	51	4	a	a	DET
admet-2684	51	5	mixture	mixture	NOUN
admet-2684	51	6	of	of	ADP
admet-2684	51	7	meoh	meoh	PROPN
admet-2684	51	8	p.a	p.a	PROPN
admet-2684	51	9	.	.	PUNCT
admet-2684	52	1	(	(	PUNCT
admet-2684	52	2	72	72	NUM
admet-2684	52	3	%	%	NOUN
admet-2684	52	4	)	)	PUNCT
admet-2684	52	5	and	and	CCONJ
admet-2684	52	6	h2o	h2o	NOUN
admet-2684	52	7	-	-	PUNCT
admet-2684	52	8	hplc	hplc	NOUN
admet-2684	52	9	mili	mili	NOUN
admet-2684	52	10	-	-	PUNCT
admet-2684	52	11	q	q	NOUN
admet-2684	52	12	grade	grade	NOUN
admet-2684	52	13	(	(	PUNCT
admet-2684	52	14	28	28	NUM
admet-2684	52	15	%	%	NOUN
admet-2684	52	16	)	)	PUNCT
admet-2684	52	17	as	as	ADP
admet-2684	52	18	a	a	DET
admet-2684	52	19	mobile	mobile	ADJ
admet-2684	52	20	phase	phase	NOUN
admet-2684	52	21	was	be	AUX
admet-2684	52	22	used	use	VERB
admet-2684	52	23	for	for	ADP
admet-2684	52	24	the	the	DET
admet-2684	52	25	determination	determination	NOUN
admet-2684	52	26	of	of	ADP
admet-2684	52	27	capacity	capacity	NOUN
admet-2684	52	28	factor	factor	NOUN
admet-2684	52	29	k.	k.	PROPN
admet-2684	53	1	isocratic	isocratic	PROPN
admet-2684	53	2	elution	elution	NOUN
admet-2684	53	3	by	by	ADP
admet-2684	53	4	a	a	DET
admet-2684	53	5	mixture	mixture	NOUN
admet-2684	53	6	of	of	ADP
admet-2684	53	7	meoh	meoh	PROPN
admet-2684	53	8	p.a	p.a	PROPN
admet-2684	53	9	.	.	PUNCT
admet-2684	54	1	(	(	PUNCT
admet-2684	54	2	72	72	NUM
admet-2684	54	3	%	%	NOUN
admet-2684	54	4	)	)	PUNCT
admet-2684	54	5	and	and	CCONJ
admet-2684	54	6	acetate	acetate	NOUN
admet-2684	54	7	-	-	PUNCT
admet-2684	54	8	buffered	buffer	VERB
admet-2684	54	9	saline	saline	NOUN
admet-2684	54	10	(	(	PUNCT
admet-2684	54	11	ph	ph	NOUN
admet-2684	54	12	7.4	7.4	NUM
admet-2684	54	13	and	and	CCONJ
admet-2684	54	14	ph	ph	ADJ
admet-2684	54	15	6.5	6.5	NUM
admet-2684	54	16	)	)	PUNCT
admet-2684	54	17	(	(	PUNCT
admet-2684	54	18	28	28	NUM
admet-2684	54	19	%	%	NOUN
admet-2684	54	20	)	)	PUNCT
admet-2684	54	21	as	as	ADP
admet-2684	54	22	a	a	DET
admet-2684	54	23	mobile	mobile	ADJ
admet-2684	54	24	phase	phase	NOUN
admet-2684	54	25	was	be	AUX
admet-2684	54	26	used	use	VERB
admet-2684	54	27	for	for	ADP
admet-2684	54	28	the	the	DET
admet-2684	54	29	determination	determination	NOUN
admet-2684	54	30	of	of	ADP
admet-2684	54	31	distribution	distribution	NOUN
admet-2684	54	32	coefficients	coefficient	NOUN
admet-2684	54	33	expressed	express	VERB
admet-2684	54	34	as	as	ADP
admet-2684	54	35	d7.4	d7.4	NUM
admet-2684	54	36	and	and	CCONJ
admet-2684	54	37	d6.5	d6.5	PROPN
admet-2684	54	38	.	.	PUNCT
admet-2684	55	1	the	the	DET
admet-2684	55	2	total	total	ADJ
admet-2684	55	3	flow	flow	NOUN
admet-2684	55	4	of	of	ADP
admet-2684	55	5	the	the	DET
admet-2684	55	6	column	column	NOUN
admet-2684	55	7	was	be	AUX
admet-2684	55	8	1.0	1.0	NUM
admet-2684	55	9	ml	ml	NOUN
admet-2684	55	10	/	/	SYM
admet-2684	55	11	min	min	NOUN
admet-2684	55	12	,	,	PUNCT
admet-2684	55	13	the	the	DET
admet-2684	55	14	injection	injection	NOUN
admet-2684	55	15	volume	volume	NOUN
admet-2684	55	16	was	be	AUX
admet-2684	55	17	20	20	NUM
admet-2684	55	18	μl	μl	ADP
admet-2684	55	19	,	,	PUNCT
admet-2684	55	20	the	the	DET
admet-2684	55	21	column	column	NOUN
admet-2684	55	22	temperature	temperature	NOUN
admet-2684	55	23	was	be	AUX
admet-2684	55	24	40	40	NUM
admet-2684	55	25	°	°	NOUN
admet-2684	55	26	c	c	NOUN
admet-2684	55	27	,	,	PUNCT
admet-2684	55	28	and	and	CCONJ
admet-2684	55	29	the	the	DET
admet-2684	55	30	sample	sample	NOUN
admet-2684	55	31	temperature	temperature	NOUN
admet-2684	55	32	was	be	AUX
admet-2684	55	33	10	10	NUM
admet-2684	55	34	°	°	NOUN
admet-2684	55	35	c	c	NOUN
admet-2684	55	36	.	.	PUNCT
admet-2684	56	1	the	the	DET
admet-2684	56	2	detection	detection	NOUN
admet-2684	56	3	wavelength	wavelength	NOUN
admet-2684	56	4	of	of	ADP
admet-2684	56	5	210	210	NUM
admet-2684	56	6	nm	nm	NOUN
admet-2684	56	7	was	be	AUX
admet-2684	56	8	chosen	choose	VERB
admet-2684	56	9	.	.	PUNCT
admet-2684	57	1	a	a	DET
admet-2684	57	2	ki	ki	PROPN
admet-2684	57	3	methanolic	methanolic	NOUN
admet-2684	57	4	solution	solution	NOUN
admet-2684	57	5	was	be	AUX
admet-2684	57	6	used	use	VERB
admet-2684	57	7	for	for	ADP
admet-2684	57	8	the	the	DET
admet-2684	57	9	determination	determination	NOUN
admet-2684	57	10	of	of	ADP
admet-2684	57	11	the	the	DET
admet-2684	57	12	dead	dead	ADJ
admet-2684	57	13	times	time	NOUN
admet-2684	57	14	(	(	PUNCT
admet-2684	57	15	td	td	NOUN
admet-2684	57	16	)	)	PUNCT
admet-2684	57	17	.	.	PUNCT
admet-2684	58	1	retention	retention	NOUN
admet-2684	58	2	times	time	NOUN
admet-2684	58	3	(	(	PUNCT
admet-2684	58	4	tr	tr	VERB
admet-2684	58	5	)	)	PUNCT
admet-2684	58	6	were	be	AUX
admet-2684	58	7	measured	measure	VERB
admet-2684	58	8	in	in	ADP
admet-2684	58	9	minutes	minute	NOUN
admet-2684	58	10	.	.	PUNCT
admet-2684	59	1	the	the	DET
admet-2684	59	2	capacity	capacity	NOUN
admet-2684	59	3	factors	factor	NOUN
admet-2684	59	4	k	k	PROPN
admet-2684	59	5	were	be	AUX
admet-2684	59	6	calculated	calculate	VERB
admet-2684	59	7	according	accord	VERB
admet-2684	59	8	to	to	ADP
admet-2684	59	9	the	the	DET
admet-2684	59	10	formula	formula	NOUN
admet-2684	59	11	k	k	NOUN
admet-2684	60	1	=	=	PUNCT
admet-2684	60	2	(	(	PUNCT
admet-2684	60	3	tr−td)/td	tr−td)/td	NOUN
admet-2684	60	4	,	,	PUNCT
admet-2684	60	5	where	where	SCONJ
admet-2684	60	6	tr	tr	PRON
admet-2684	60	7	is	be	AUX
admet-2684	60	8	the	the	DET
admet-2684	60	9	retention	retention	NOUN
admet-2684	60	10	time	time	NOUN
admet-2684	60	11	of	of	ADP
admet-2684	60	12	the	the	DET
admet-2684	60	13	solute	solute	NOUN
admet-2684	60	14	,	,	PUNCT
admet-2684	60	15	and	and	CCONJ
admet-2684	60	16	td	td	NOUN
admet-2684	60	17	is	be	AUX
admet-2684	60	18	the	the	DET
admet-2684	60	19	dead	dead	ADJ
admet-2684	60	20	time	time	NOUN
admet-2684	60	21	obtained	obtain	VERB
admet-2684	60	22	using	use	VERB
admet-2684	60	23	an	an	DET
admet-2684	60	24	unretained	unretained	ADJ
admet-2684	60	25	analyte	analyte	NOUN
admet-2684	60	26	.	.	PUNCT
admet-2684	61	1	the	the	DET
admet-2684	61	2	distribution	distribution	NOUN
admet-2684	61	3	coefficients	coefficient	NOUN
admet-2684	61	4	dph	dph	PROPN
admet-2684	61	5	were	be	AUX
admet-2684	61	6	calculated	calculate	VERB
admet-2684	61	7	according	accord	VERB
admet-2684	61	8	to	to	ADP
admet-2684	61	9	the	the	DET
admet-2684	61	10	formula	formula	NOUN
admet-2684	61	11	dph	dph	NOUN
admet-2684	61	12	=	=	PUNCT
admet-2684	61	13	(	(	PUNCT
admet-2684	61	14	tr−td)/td	tr−td)/td	NOUN
admet-2684	61	15	.	.	PUNCT
admet-2684	62	1	each	each	DET
admet-2684	62	2	experiment	experiment	NOUN
admet-2684	62	3	was	be	AUX
admet-2684	62	4	repeated	repeat	VERB
admet-2684	62	5	three	three	NUM
admet-2684	62	6	times	time	NOUN
admet-2684	62	7	.	.	PUNCT
admet-2684	63	1	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	63	2	screening	screening	NOUN
admet-2684	63	3	in	in	ADP
admet-2684	63	4	vitro	vitro	X
admet-2684	63	5	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	63	6	activity	activity	NOUN
admet-2684	63	7	of	of	ADP
admet-2684	63	8	the	the	DET
admet-2684	63	9	synthesized	synthesize	VERB
admet-2684	63	10	compounds	compound	NOUN
admet-2684	63	11	was	be	AUX
admet-2684	63	12	evaluated	evaluate	VERB
admet-2684	63	13	against	against	ADP
admet-2684	63	14	three	three	NUM
admet-2684	63	15	clinical	clinical	ADJ
admet-2684	63	16	isolates	isolate	NOUN
admet-2684	63	17	of	of	ADP
admet-2684	63	18	methicillin	methicillin	NOUN
admet-2684	63	19	-	-	PUNCT
admet-2684	63	20	resistant	resistant	ADJ
admet-2684	63	21	s.	s.	PROPN
admet-2684	63	22	aureus	aureus	PROPN
admet-2684	63	23	:	:	PUNCT
admet-2684	63	24	clinical	clinical	ADJ
admet-2684	63	25	isolate	isolate	NOUN
admet-2684	63	26	of	of	ADP
admet-2684	63	27	animal	animal	NOUN
admet-2684	63	28	origin	origin	NOUN
admet-2684	63	29	,	,	PUNCT
admet-2684	63	30	mrsa	mrsa	NOUN
admet-2684	63	31	63718	63718	NUM
admet-2684	63	32	(	(	PUNCT
admet-2684	63	33	department	department	NOUN
admet-2684	63	34	of	of	ADP
admet-2684	63	35	infectious	infectious	ADJ
admet-2684	63	36	diseases	disease	NOUN
admet-2684	63	37	and	and	CCONJ
admet-2684	63	38	microbiology	microbiology	NOUN
admet-2684	63	39	,	,	PUNCT
admet-2684	63	40	faculty	faculty	NOUN
admet-2684	63	41	of	of	ADP
admet-2684	63	42	veterinary	veterinary	ADJ
admet-2684	63	43	medicine	medicine	NOUN
admet-2684	63	44	,	,	PUNCT
admet-2684	63	45	university	university	NOUN
admet-2684	63	46	of	of	ADP
admet-2684	63	47	veterinary	veterinary	ADJ
admet-2684	63	48	sciences	science	NOUN
admet-2684	63	49	brno	brno	NOUN
admet-2684	63	50	,	,	PUNCT
admet-2684	63	51	czech	czech	PROPN
admet-2684	63	52	republic	republic	NOUN
admet-2684	63	53	)	)	PUNCT
admet-2684	64	1	[	[	X
admet-2684	64	2	54	54	NUM
admet-2684	64	3	]	]	PUNCT
admet-2684	64	4	,	,	PUNCT
admet-2684	64	5	carrying	carry	VERB
admet-2684	64	6	the	the	DET
admet-2684	64	7	meca	meca	NOUN
admet-2684	64	8	gene	gene	NOUN
admet-2684	64	9	[	[	X
admet-2684	64	10	55	55	NUM
admet-2684	64	11	]	]	PUNCT
admet-2684	64	12	;	;	PUNCT
admet-2684	64	13	and	and	CCONJ
admet-2684	64	14	mrsa	mrsa	NOUN
admet-2684	64	15	sa	sa	NOUN
admet-2684	64	16	630	630	NUM
admet-2684	64	17	and	and	CCONJ
admet-2684	64	18	mrsa	mrsa	NOUN
admet-2684	64	19	sa	sa	PROPN
admet-2684	64	20	3202	3202	PROPN
admet-2684	65	1	[	[	X
admet-2684	65	2	54	54	NUM
admet-2684	65	3	]	]	X
admet-2684	65	4	(	(	PUNCT
admet-2684	65	5	national	national	PROPN
admet-2684	65	6	institute	institute	PROPN
admet-2684	65	7	of	of	ADP
admet-2684	65	8	public	public	PROPN
admet-2684	65	9	health	health	NOUN
admet-2684	65	10	,	,	PUNCT
admet-2684	65	11	prague	prague	NOUN
admet-2684	65	12	,	,	PUNCT
admet-2684	65	13	czech	czech	PROPN
admet-2684	65	14	republic	republic	NOUN
admet-2684	65	15	)	)	PUNCT
admet-2684	65	16	,	,	PUNCT
admet-2684	65	17	both	both	PRON
admet-2684	65	18	of	of	ADP
admet-2684	65	19	human	human	ADJ
admet-2684	65	20	origin	origin	NOUN
admet-2684	65	21	.	.	PUNCT
admet-2684	66	1	suspected	suspect	VERB
admet-2684	66	2	colonies	colony	NOUN
admet-2684	66	3	were	be	AUX
admet-2684	66	4	confirmed	confirm	VERB
admet-2684	66	5	by	by	ADP
admet-2684	66	6	pcr	pcr	PROPN
admet-2684	66	7	;	;	PUNCT
admet-2684	66	8	a	a	DET
admet-2684	66	9	108bp	108bp	ADJ
admet-2684	66	10	fragment	fragment	NOUN
admet-2684	66	11	specific	specific	NOUN
admet-2684	66	12	to	to	ADP
admet-2684	66	13	s.	s.	PROPN
admet-2684	66	14	aureus	aureus	PROPN
admet-2684	66	15	was	be	AUX
admet-2684	66	16	detected	detect	VERB
admet-2684	66	17	[	[	X
admet-2684	66	18	56	56	NUM
admet-2684	66	19	]	]	PUNCT
admet-2684	66	20	.	.	PUNCT
admet-2684	67	1	all	all	DET
admet-2684	67	2	isolates	isolate	NOUN
admet-2684	67	3	were	be	AUX
admet-2684	67	4	tested	test	VERB
admet-2684	67	5	for	for	ADP
admet-2684	67	6	the	the	DET
admet-2684	67	7	presence	presence	NOUN
admet-2684	67	8	of	of	ADP
admet-2684	67	9	the	the	DET
admet-2684	67	10	meca	meca	PROPN
admet-2684	67	11	gene	gene	NOUN
admet-2684	67	12	encoding	encode	VERB
admet-2684	67	13	methicillin	methicillin	NOUN
admet-2684	67	14	resistance	resistance	NOUN
admet-2684	67	15	[	[	X
admet-2684	67	16	57	57	NUM
admet-2684	67	17	]	]	PUNCT
admet-2684	67	18	.	.	PUNCT
admet-2684	68	1	these	these	DET
admet-2684	68	2	three	three	NUM
admet-2684	68	3	clinical	clinical	ADJ
admet-2684	68	4	isolates	isolate	NOUN
admet-2684	68	5	were	be	AUX
admet-2684	68	6	classified	classify	VERB
admet-2684	68	7	as	as	ADP
admet-2684	68	8	vancomycin	vancomycin	NOUN
admet-2684	68	9	-	-	PUNCT
admet-2684	68	10	susceptible	susceptible	ADJ
admet-2684	68	11	(	(	PUNCT
admet-2684	68	12	but	but	CCONJ
admet-2684	68	13	with	with	ADP
admet-2684	68	14	higher	high	ADJ
admet-2684	68	15	mic	mic	NOUN
admet-2684	68	16	of	of	ADP
admet-2684	68	17	vancomycin	vancomycin	PROPN
admet-2684	68	18	equal	equal	ADJ
admet-2684	68	19	to	to	ADP
admet-2684	68	20	2	2	NUM
admet-2684	68	21	μg	μg	NOUN
admet-2684	68	22	/	/	SYM
admet-2684	68	23	ml	ml	PROPN
admet-2684	68	24	(	(	PUNCT
admet-2684	68	25	va2	va2	NOUN
admet-2684	68	26	-	-	PUNCT
admet-2684	68	27	mrsa	mrsa	NOUN
admet-2684	68	28	)	)	PUNCT
admet-2684	68	29	within	within	ADP
admet-2684	68	30	the	the	DET
admet-2684	68	31	susceptible	susceptible	ADJ
admet-2684	68	32	range	range	NOUN
admet-2684	68	33	for	for	ADP
admet-2684	68	34	mrsa	mrsa	NOUN
admet-2684	68	35	63718	63718	NUM
admet-2684	68	36	)	)	PUNCT
admet-2684	68	37	methicillin	methicillin	NOUN
admet-2684	68	38	-	-	PUNCT
admet-2684	68	39	resistant	resistant	ADJ
admet-2684	68	40	s.	s.	PROPN
admet-2684	68	41	aureus	aureus	PROPN
admet-2684	68	42	(	(	PUNCT
admet-2684	68	43	vs	vs	NOUN
admet-2684	68	44	-	-	PUNCT
admet-2684	68	45	mrsa	mrsa	NOUN
admet-2684	68	46	)	)	PUNCT
admet-2684	69	1	[	[	X
admet-2684	69	2	54	54	NUM
admet-2684	69	3	]	]	PUNCT
admet-2684	69	4	.	.	PUNCT
admet-2684	70	1	vancomycin	vancomycin	PROPN
admet-2684	70	2	-	-	PUNCT
admet-2684	70	3	susceptible	susceptible	ADJ
admet-2684	70	4	methicillin	methicillin	NOUN
admet-2684	70	5	-	-	PUNCT
admet-2684	70	6	susceptible	susceptible	ADJ
admet-2684	70	7	s.	s.	PROPN
admet-2684	70	8	aureus	aureus	PROPN
admet-2684	70	9	(	(	PUNCT
admet-2684	70	10	vs	vs	NOUN
admet-2684	70	11	-	-	PUNCT
admet-2684	70	12	mssa	mssa	ADJ
admet-2684	70	13	)	)	PUNCT
admet-2684	70	14	atcc	atcc	PROPN
admet-2684	70	15	29213	29213	NUM
admet-2684	70	16	,	,	PUNCT
admet-2684	70	17	obtained	obtain	VERB
admet-2684	70	18	from	from	ADP
admet-2684	70	19	the	the	DET
admet-2684	70	20	american	american	ADJ
admet-2684	70	21	type	type	NOUN
admet-2684	70	22	culture	culture	NOUN
admet-2684	70	23	collection	collection	NOUN
admet-2684	70	24	,	,	PUNCT
admet-2684	70	25	was	be	AUX
admet-2684	70	26	used	use	VERB
admet-2684	70	27	as	as	ADP
admet-2684	70	28	the	the	DET
admet-2684	70	29	reference	reference	NOUN
admet-2684	70	30	and	and	CCONJ
admet-2684	70	31	quality	quality	NOUN
admet-2684	70	32	control	control	NOUN
admet-2684	70	33	strain	strain	NOUN
admet-2684	70	34	.	.	PUNCT
admet-2684	71	1	the	the	DET
admet-2684	71	2	minimum	minimum	ADJ
admet-2684	71	3	inhibitory	inhibitory	ADJ
admet-2684	71	4	concentrations	concentration	NOUN
admet-2684	71	5	(	(	PUNCT
admet-2684	71	6	mics	mic	NOUN
admet-2684	71	7	)	)	PUNCT
admet-2684	71	8	were	be	AUX
admet-2684	71	9	evaluated	evaluate	VERB
admet-2684	71	10	by	by	ADP
admet-2684	71	11	the	the	DET
admet-2684	71	12	microtitration	microtitration	NOUN
admet-2684	71	13	broth	broth	NOUN
admet-2684	71	14	method	method	NOUN
admet-2684	71	15	according	accord	VERB
admet-2684	71	16	to	to	ADP
admet-2684	71	17	the	the	DET
admet-2684	71	18	clsi	clsi	NOUN
admet-2684	72	1	[	[	X
admet-2684	72	2	58,59	58,59	X
admet-2684	72	3	]	]	PUNCT
admet-2684	72	4	with	with	ADP
admet-2684	72	5	some	some	DET
admet-2684	72	6	modifications	modification	NOUN
admet-2684	72	7	.	.	PUNCT
admet-2684	73	1	the	the	DET
admet-2684	73	2	compounds	compound	NOUN
admet-2684	73	3	were	be	AUX
admet-2684	73	4	dissolved	dissolve	VERB
admet-2684	73	5	in	in	ADP
admet-2684	73	6	dmso	dmso	NOUN
admet-2684	73	7	(	(	PUNCT
admet-2684	73	8	sigma	sigma	PROPN
admet-2684	73	9	,	,	PUNCT
admet-2684	73	10	st	st	PROPN
admet-2684	73	11	.	.	PROPN
admet-2684	73	12	louis	louis	PROPN
admet-2684	73	13	,	,	PUNCT
admet-2684	73	14	mo	mo	PROPN
admet-2684	73	15	,	,	PUNCT
admet-2684	73	16	usa	usa	PROPN
admet-2684	73	17	)	)	PUNCT
admet-2684	73	18	to	to	PART
admet-2684	73	19	get	get	VERB
admet-2684	73	20	a	a	DET
admet-2684	73	21	concentration	concentration	NOUN
admet-2684	73	22	10	10	NUM
admet-2684	73	23	µg	µg	NOUN
admet-2684	73	24	/	/	SYM
admet-2684	73	25	ml	ml	NOUN
admet-2684	73	26	and	and	CCONJ
admet-2684	73	27	diluted	dilute	VERB
admet-2684	73	28	in	in	ADP
admet-2684	73	29	a	a	DET
admet-2684	73	30	microtitration	microtitration	NOUN
admet-2684	73	31	plate	plate	NOUN
admet-2684	73	32	in	in	ADP
admet-2684	73	33	a	a	DET
admet-2684	73	34	medium	medium	ADJ
admet-2684	73	35	cation	cation	NOUN
admet-2684	73	36	adjusted	adjust	VERB
admet-2684	73	37	mueller	mueller	PROPN
admet-2684	73	38	-	-	PUNCT
admet-2684	73	39	hinton	hinton	PROPN
admet-2684	73	40	(	(	PUNCT
admet-2684	73	41	camh	camh	ADJ
admet-2684	73	42	,	,	PUNCT
admet-2684	73	43	oxoid	oxoid	PROPN
admet-2684	73	44	,	,	PUNCT
admet-2684	73	45	basingstoke	basingstoke	PROPN
admet-2684	73	46	,	,	PUNCT
admet-2684	73	47	uk	uk	PROPN
admet-2684	73	48	)	)	PUNCT
admet-2684	73	49	to	to	PART
admet-2684	73	50	reach	reach	VERB
admet-2684	73	51	the	the	DET
admet-2684	73	52	final	final	ADJ
admet-2684	73	53	concentration	concentration	NOUN
admet-2684	73	54	of	of	ADP
admet-2684	73	55	256	256	NUM
admet-2684	73	56	-	-	SYM
admet-2684	73	57	0.0625	0.0625	NUM
admet-2684	73	58	µg	µg	NOUN
admet-2684	73	59	/	/	SYM
admet-2684	73	60	ml	ml	NOUN
admet-2684	73	61	.	.	PUNCT
admet-2684	74	1	the	the	DET
admet-2684	74	2	plate	plate	NOUN
admet-2684	74	3	was	be	AUX
admet-2684	74	4	inoculated	inoculate	VERB
admet-2684	74	5	by	by	ADP
admet-2684	74	6	the	the	DET
admet-2684	74	7	tested	test	VERB
admet-2684	74	8	microorganisms	microorganism	NOUN
admet-2684	74	9	.	.	PUNCT
admet-2684	75	1	the	the	DET
admet-2684	75	2	final	final	ADJ
admet-2684	75	3	concentration	concentration	NOUN
admet-2684	75	4	of	of	ADP
admet-2684	75	5	bacterial	bacterial	ADJ
admet-2684	75	6	cells	cell	NOUN
admet-2684	75	7	was	be	AUX
admet-2684	75	8	105	105	NUM
admet-2684	75	9	for	for	ADP
admet-2684	75	10	bacteria	bacteria	NOUN
admet-2684	75	11	.	.	PUNCT
admet-2684	76	1	ampicillin	ampicillin	PROPN
admet-2684	76	2	and	and	CCONJ
admet-2684	76	3	ciprofloxacin	ciprofloxacin	PROPN
admet-2684	76	4	(	(	PUNCT
admet-2684	76	5	sigma	sigma	PROPN
admet-2684	76	6	)	)	PUNCT
admet-2684	76	7	were	be	AUX
admet-2684	76	8	used	use	VERB
admet-2684	76	9	as	as	ADP
admet-2684	76	10	reference	reference	NOUN
admet-2684	76	11	drugs	drug	NOUN
admet-2684	76	12	.	.	PUNCT
admet-2684	77	1	a	a	DET
admet-2684	77	2	drug	drug	NOUN
admet-2684	77	3	-	-	PUNCT
admet-2684	77	4	free	free	ADJ
admet-2684	77	5	control	control	NOUN
admet-2684	77	6	and	and	CCONJ
admet-2684	77	7	a	a	DET
admet-2684	77	8	sterility	sterility	NOUN
admet-2684	77	9	control	control	NOUN
admet-2684	77	10	were	be	AUX
admet-2684	77	11	included	include	VERB
admet-2684	77	12	.	.	PUNCT
admet-2684	78	1	the	the	DET
admet-2684	78	2	plates	plate	NOUN
admet-2684	78	3	were	be	AUX
admet-2684	78	4	incubated	incubate	VERB
admet-2684	78	5	for	for	ADP
admet-2684	78	6	24	24	NUM
admet-2684	78	7	h	h	NOUN
admet-2684	78	8	at	at	ADP
admet-2684	78	9	37	37	NUM
admet-2684	78	10	°	°	NOUN
admet-2684	78	11	c	c	NOUN
admet-2684	78	12	.	.	PUNCT
admet-2684	79	1	after	after	ADP
admet-2684	79	2	static	static	ADJ
admet-2684	79	3	incubation	incubation	NOUN
admet-2684	79	4	in	in	ADP
admet-2684	79	5	the	the	DET
admet-2684	79	6	darkness	darkness	NOUN
admet-2684	79	7	in	in	ADP
admet-2684	79	8	an	an	DET
admet-2684	79	9	aerobic	aerobic	ADJ
admet-2684	79	10	atmosphere	atmosphere	NOUN
admet-2684	79	11	,	,	PUNCT
admet-2684	79	12	the	the	DET
admet-2684	79	13	mic	mic	NOUN
admet-2684	79	14	was	be	AUX
admet-2684	79	15	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	PROPN
admet-2684	79	16	l.	l.	PROPN
admet-2684	79	17	vrablova	vrablova	PROPN
admet-2684	79	18	et	et	PROPN
admet-2684	79	19	al	al	PROPN
admet-2684	79	20	.	.	PROPN
admet-2684	79	21	admet	admet	PROPN
admet-2684	79	22	&	&	CCONJ
admet-2684	79	23	dmpk	dmpk	PROPN
admet-2684	79	24	13(2	13(2	PROPN
admet-2684	79	25	)	)	PUNCT
admet-2684	79	26	(	(	PUNCT
admet-2684	79	27	2025	2025	NUM
admet-2684	79	28	)	)	PUNCT
admet-2684	79	29	2684	2684	NUM
admet-2684	79	30	4	4	NUM
admet-2684	79	31	visually	visually	ADV
admet-2684	79	32	evaluated	evaluate	VERB
admet-2684	79	33	as	as	ADP
admet-2684	79	34	the	the	DET
admet-2684	79	35	lowest	low	ADJ
admet-2684	79	36	concentration	concentration	NOUN
admet-2684	79	37	of	of	ADP
admet-2684	79	38	the	the	DET
admet-2684	79	39	tested	test	VERB
admet-2684	79	40	compound	compound	NOUN
admet-2684	79	41	,	,	PUNCT
admet-2684	79	42	which	which	PRON
admet-2684	79	43	completely	completely	ADV
admet-2684	79	44	inhibited	inhibit	VERB
admet-2684	79	45	the	the	DET
admet-2684	79	46	growth	growth	NOUN
admet-2684	79	47	of	of	ADP
admet-2684	79	48	the	the	DET
admet-2684	79	49	microorganism	microorganism	NOUN
admet-2684	79	50	.	.	PUNCT
admet-2684	80	1	the	the	DET
admet-2684	80	2	experiments	experiment	NOUN
admet-2684	80	3	were	be	AUX
admet-2684	80	4	repeated	repeat	VERB
admet-2684	80	5	three	three	NUM
admet-2684	80	6	times	time	NOUN
admet-2684	80	7	.	.	PUNCT
admet-2684	81	1	mtt	mtt	PROPN
admet-2684	81	2	assay	assay	PROPN
admet-2684	81	3	compounds	compound	NOUN
admet-2684	81	4	were	be	AUX
admet-2684	81	5	prepared	prepare	VERB
admet-2684	81	6	as	as	SCONJ
admet-2684	81	7	previously	previously	ADV
admet-2684	81	8	stated	state	VERB
admet-2684	81	9	and	and	CCONJ
admet-2684	81	10	diluted	dilute	VERB
admet-2684	81	11	in	in	ADP
admet-2684	81	12	camh	camh	ADJ
admet-2684	81	13	broth	broth	NOUN
admet-2684	81	14	for	for	ADP
admet-2684	81	15	s.	s.	PROPN
admet-2684	81	16	aureus	aureus	PROPN
admet-2684	81	17	to	to	PART
admet-2684	81	18	achieve	achieve	VERB
admet-2684	81	19	the	the	DET
admet-2684	81	20	desired	desire	VERB
admet-2684	81	21	final	final	ADJ
admet-2684	81	22	concentrations	concentration	NOUN
admet-2684	81	23	.	.	PUNCT
admet-2684	82	1	s.	s.	PROPN
admet-2684	82	2	aureus	aureus	PROPN
admet-2684	82	3	bacterial	bacterial	ADJ
admet-2684	82	4	suspension	suspension	NOUN
admet-2684	82	5	in	in	ADP
admet-2684	82	6	sterile	sterile	ADJ
admet-2684	82	7	distilled	distil	VERB
admet-2684	82	8	water	water	NOUN
admet-2684	82	9	at	at	ADP
admet-2684	82	10	0.5	0.5	NUM
admet-2684	82	11	mcfarland	mcfarland	PROPN
admet-2684	82	12	was	be	AUX
admet-2684	82	13	diluted	dilute	VERB
admet-2684	82	14	1:3	1:3	NUM
admet-2684	82	15	.	.	PUNCT
admet-2684	83	1	inocula	inocula	PROPN
admet-2684	83	2	were	be	AUX
admet-2684	83	3	added	add	VERB
admet-2684	83	4	to	to	ADP
admet-2684	83	5	each	each	DET
admet-2684	83	6	well	well	NOUN
admet-2684	83	7	by	by	ADP
admet-2684	83	8	multi	multi	ADJ
admet-2684	83	9	-	-	NOUN
admet-2684	83	10	inoculator	inoculator	ADJ
admet-2684	83	11	.	.	PUNCT
admet-2684	84	1	diluted	dilute	VERB
admet-2684	84	2	mycobacteria	mycobacterium	NOUN
admet-2684	84	3	in	in	ADP
admet-2684	84	4	broth	broth	NOUN
admet-2684	84	5	free	free	ADJ
admet-2684	84	6	from	from	ADP
admet-2684	84	7	inhibiting	inhibit	VERB
admet-2684	84	8	compounds	compound	NOUN
admet-2684	84	9	were	be	AUX
admet-2684	84	10	used	use	VERB
admet-2684	84	11	as	as	ADP
admet-2684	84	12	the	the	DET
admet-2684	84	13	growth	growth	NOUN
admet-2684	84	14	control	control	NOUN
admet-2684	84	15	.	.	PUNCT
admet-2684	85	1	all	all	DET
admet-2684	85	2	compounds	compound	NOUN
admet-2684	85	3	were	be	AUX
admet-2684	85	4	prepared	prepare	VERB
admet-2684	85	5	in	in	ADP
admet-2684	85	6	duplicate	duplicate	NOUN
admet-2684	85	7	.	.	PUNCT
admet-2684	86	1	plates	plate	NOUN
admet-2684	86	2	were	be	AUX
admet-2684	86	3	incubated	incubate	VERB
admet-2684	86	4	at	at	ADP
admet-2684	86	5	37	37	NUM
admet-2684	86	6	°	°	NOUN
admet-2684	86	7	c	c	NOUN
admet-2684	86	8	for	for	ADP
admet-2684	86	9	24	24	NUM
admet-2684	86	10	h	h	NOUN
admet-2684	86	11	for	for	ADP
admet-2684	86	12	s.	s.	PROPN
admet-2684	86	13	aureus	aureus	PROPN
admet-2684	86	14	.	.	PUNCT
admet-2684	87	1	after	after	ADP
admet-2684	87	2	the	the	DET
admet-2684	87	3	incubation	incubation	NOUN
admet-2684	87	4	period	period	NOUN
admet-2684	87	5	,	,	PUNCT
admet-2684	87	6	10	10	NUM
admet-2684	87	7	%	%	NOUN
admet-2684	87	8	well	well	INTJ
admet-2684	87	9	volume	volume	NOUN
admet-2684	87	10	of	of	ADP
admet-2684	87	11	mtt	mtt	NOUN
admet-2684	87	12	(	(	PUNCT
admet-2684	87	13	3-(4,5	3-(4,5	PROPN
admet-2684	87	14	-	-	PUNCT
admet-2684	87	15	dimethylthiazol-2	dimethylthiazol-2	NUM
admet-2684	87	16	-	-	PUNCT
admet-2684	87	17	yl)-2,5	yl)-2,5	NOUN
admet-2684	87	18	-	-	PUNCT
admet-2684	87	19	diphenyltetrazolium	diphenyltetrazolium	NOUN
admet-2684	87	20	bromide	bromide	NOUN
admet-2684	87	21	)	)	PUNCT
admet-2684	87	22	reagent	reagent	NOUN
admet-2684	87	23	(	(	PUNCT
admet-2684	87	24	sigma	sigma	PROPN
admet-2684	87	25	)	)	PUNCT
admet-2684	87	26	was	be	AUX
admet-2684	87	27	mixed	mix	VERB
admet-2684	87	28	into	into	ADP
admet-2684	87	29	each	each	DET
admet-2684	87	30	well	well	NOUN
admet-2684	87	31	and	and	CCONJ
admet-2684	87	32	incubated	incubate	VERB
admet-2684	87	33	at	at	ADP
admet-2684	87	34	37	37	NUM
admet-2684	87	35	°	°	NOUN
admet-2684	87	36	c	c	NOUN
admet-2684	87	37	for	for	ADP
admet-2684	87	38	1	1	NUM
admet-2684	87	39	h	h	NOUN
admet-2684	87	40	for	for	ADP
admet-2684	87	41	s.	s.	PROPN
admet-2684	87	42	aureus	aureus	PROPN
admet-2684	87	43	.	.	PUNCT
admet-2684	88	1	then	then	ADV
admet-2684	88	2	100	100	NUM
admet-2684	88	3	µl	µl	NOUN
admet-2684	88	4	of	of	ADP
admet-2684	88	5	17	17	NUM
admet-2684	88	6	%	%	NOUN
admet-2684	88	7	sodium	sodium	NOUN
admet-2684	88	8	dodecyl	dodecyl	NOUN
admet-2684	88	9	sulphate	sulphate	VERB
admet-2684	88	10	in	in	ADP
admet-2684	88	11	40	40	NUM
admet-2684	88	12	%	%	NOUN
admet-2684	88	13	dimethylformamide	dimethylformamide	NOUN
admet-2684	88	14	was	be	AUX
admet-2684	88	15	added	add	VERB
admet-2684	88	16	to	to	ADP
admet-2684	88	17	each	each	DET
admet-2684	88	18	well	well	ADV
admet-2684	88	19	.	.	PUNCT
admet-2684	89	1	the	the	DET
admet-2684	89	2	plates	plate	NOUN
admet-2684	89	3	were	be	AUX
admet-2684	89	4	read	read	VERB
admet-2684	89	5	at	at	ADP
admet-2684	89	6	570	570	NUM
admet-2684	89	7	nm	nm	NOUN
admet-2684	89	8	.	.	PUNCT
admet-2684	90	1	the	the	DET
admet-2684	90	2	absorbance	absorbance	NOUN
admet-2684	90	3	readings	reading	VERB
admet-2684	90	4	from	from	ADP
admet-2684	90	5	the	the	DET
admet-2684	90	6	cells	cell	NOUN
admet-2684	90	7	grown	grow	VERB
admet-2684	90	8	in	in	ADP
admet-2684	90	9	the	the	DET
admet-2684	90	10	presence	presence	NOUN
admet-2684	90	11	of	of	ADP
admet-2684	90	12	the	the	DET
admet-2684	90	13	tested	test	VERB
admet-2684	90	14	compounds	compound	NOUN
admet-2684	90	15	were	be	AUX
admet-2684	90	16	compared	compare	VERB
admet-2684	90	17	with	with	ADP
admet-2684	90	18	uninhibited	uninhibited	ADJ
admet-2684	90	19	cell	cell	NOUN
admet-2684	90	20	growth	growth	NOUN
admet-2684	90	21	to	to	PART
admet-2684	90	22	determine	determine	VERB
admet-2684	90	23	the	the	DET
admet-2684	90	24	relative	relative	ADJ
admet-2684	90	25	percent	percent	NOUN
admet-2684	90	26	inhibition	inhibition	NOUN
admet-2684	90	27	.	.	PUNCT
admet-2684	91	1	the	the	DET
admet-2684	91	2	percent	percent	NOUN
admet-2684	91	3	inhibition	inhibition	NOUN
admet-2684	91	4	was	be	AUX
admet-2684	91	5	determined	determine	VERB
admet-2684	91	6	through	through	ADP
admet-2684	91	7	the	the	DET
admet-2684	91	8	mtt	mtt	NOUN
admet-2684	91	9	assay	assay	VERB
admet-2684	91	10	.	.	PUNCT
admet-2684	92	1	the	the	DET
admet-2684	92	2	percent	percent	NOUN
admet-2684	92	3	viability	viability	NOUN
admet-2684	92	4	is	be	AUX
admet-2684	92	5	calculated	calculate	VERB
admet-2684	92	6	through	through	ADP
admet-2684	92	7	the	the	DET
admet-2684	92	8	comparison	comparison	NOUN
admet-2684	92	9	of	of	ADP
admet-2684	92	10	a	a	DET
admet-2684	92	11	measured	measured	ADJ
admet-2684	92	12	value	value	NOUN
admet-2684	92	13	and	and	CCONJ
admet-2684	92	14	that	that	PRON
admet-2684	92	15	of	of	ADP
admet-2684	92	16	the	the	DET
admet-2684	92	17	uninhibited	uninhibited	ADJ
admet-2684	92	18	control	control	NOUN
admet-2684	92	19	:	:	PUNCT
admet-2684	92	20	viability	viability	NOUN
admet-2684	92	21	=	=	SYM
admet-2684	92	22	(	(	PUNCT
admet-2684	92	23	od570e	od570e	VERB
admet-2684	92	24	/	/	SYM
admet-2684	92	25	od570p)×100	od570p)×100	NOUN
admet-2684	92	26	,	,	PUNCT
admet-2684	92	27	where	where	SCONJ
admet-2684	92	28	od570e	od570e	VERB
admet-2684	92	29	is	be	AUX
admet-2684	92	30	the	the	DET
admet-2684	92	31	reading	reading	NOUN
admet-2684	92	32	from	from	ADP
admet-2684	92	33	the	the	DET
admet-2684	92	34	compound	compound	NOUN
admet-2684	92	35	-	-	PUNCT
admet-2684	92	36	exposed	expose	VERB
admet-2684	92	37	cells	cell	NOUN
admet-2684	92	38	,	,	PUNCT
admet-2684	92	39	while	while	SCONJ
admet-2684	92	40	od570p	od570p	PROPN
admet-2684	92	41	is	be	AUX
admet-2684	92	42	the	the	DET
admet-2684	92	43	reading	reading	NOUN
admet-2684	92	44	from	from	ADP
admet-2684	92	45	the	the	DET
admet-2684	92	46	uninhibited	uninhibited	ADJ
admet-2684	92	47	cells	cell	NOUN
admet-2684	92	48	(	(	PUNCT
admet-2684	92	49	positive	positive	ADJ
admet-2684	92	50	control	control	NOUN
admet-2684	92	51	)	)	PUNCT
admet-2684	92	52	.	.	PUNCT
admet-2684	93	1	cytotoxic	cytotoxic	ADJ
admet-2684	93	2	potential	potential	NOUN
admet-2684	93	3	is	be	AUX
admet-2684	93	4	determined	determine	VERB
admet-2684	93	5	by	by	ADP
admet-2684	93	6	a	a	DET
admet-2684	93	7	percent	percent	NOUN
admet-2684	93	8	viability	viability	NOUN
admet-2684	93	9	of	of	ADP
admet-2684	93	10	<	<	X
admet-2684	93	11	70	70	NUM
admet-2684	93	12	%	%	NOUN
admet-2684	94	1	[	[	X
admet-2684	94	2	60,61	60,61	NOUN
admet-2684	94	3	]	]	PUNCT
admet-2684	94	4	.	.	PUNCT
admet-2684	95	1	cytotoxicity	cytotoxicity	NOUN
admet-2684	95	2	assay	assay	VERB
admet-2684	95	3	cytotoxicity	cytotoxicity	NOUN
admet-2684	95	4	of	of	ADP
admet-2684	95	5	the	the	DET
admet-2684	95	6	compounds	compound	NOUN
admet-2684	95	7	was	be	AUX
admet-2684	95	8	determined	determine	VERB
admet-2684	95	9	using	use	VERB
admet-2684	95	10	an	an	DET
admet-2684	95	11	ldh	ldh	NOUN
admet-2684	95	12	assay	assay	NOUN
admet-2684	95	13	kit	kit	NOUN
admet-2684	95	14	(	(	PUNCT
admet-2684	95	15	roche	roche	PROPN
admet-2684	95	16	,	,	PUNCT
admet-2684	95	17	mannheim	mannheim	PROPN
admet-2684	95	18	,	,	PUNCT
admet-2684	95	19	germany	germany	PROPN
admet-2684	95	20	)	)	PUNCT
admet-2684	95	21	as	as	SCONJ
admet-2684	95	22	described	describe	VERB
admet-2684	95	23	previously	previously	ADV
admet-2684	95	24	[	[	X
admet-2684	95	25	31	31	NUM
admet-2684	95	26	]	]	PUNCT
admet-2684	95	27	.	.	PUNCT
admet-2684	96	1	human	human	ADJ
admet-2684	96	2	monocytic	monocytic	ADJ
admet-2684	96	3	leukemia	leukemia	NOUN
admet-2684	96	4	thp-1	thp-1	ADP
admet-2684	96	5	cells	cell	NOUN
admet-2684	96	6	(	(	PUNCT
admet-2684	96	7	european	european	ADJ
admet-2684	96	8	collection	collection	NOUN
admet-2684	96	9	of	of	ADP
admet-2684	96	10	cell	cell	NOUN
admet-2684	96	11	cultures	culture	NOUN
admet-2684	96	12	,	,	PUNCT
admet-2684	96	13	salisbury	salisbury	PROPN
admet-2684	96	14	,	,	PUNCT
admet-2684	96	15	uk	uk	PROPN
admet-2684	96	16	)	)	PUNCT
admet-2684	96	17	were	be	AUX
admet-2684	96	18	exposed	expose	VERB
admet-2684	96	19	for	for	ADP
admet-2684	96	20	24	24	NUM
admet-2684	96	21	h	h	NOUN
admet-2684	96	22	at	at	ADP
admet-2684	96	23	37	37	NUM
admet-2684	96	24	°	°	ADP
admet-2684	96	25	c	c	NOUN
admet-2684	96	26	to	to	ADP
admet-2684	96	27	various	various	ADJ
admet-2684	96	28	compound	compound	NOUN
admet-2684	96	29	concentrations	concentration	NOUN
admet-2684	96	30	ranging	range	VERB
admet-2684	96	31	from	from	ADP
admet-2684	96	32	0.37	0.37	NUM
admet-2684	96	33	to	to	ADP
admet-2684	96	34	30	30	NUM
admet-2684	96	35	μm	μm	NOUN
admet-2684	96	36	in	in	ADP
admet-2684	96	37	rpmi	rpmi	NOUN
admet-2684	96	38	1640	1640	NUM
admet-2684	96	39	medium	medium	NOUN
admet-2684	96	40	.	.	PUNCT
admet-2684	97	1	for	for	ADP
admet-2684	97	2	ldh	ldh	ADJ
admet-2684	97	3	assays	assay	NOUN
admet-2684	97	4	,	,	PUNCT
admet-2684	97	5	cells	cell	NOUN
admet-2684	97	6	were	be	AUX
admet-2684	97	7	seeded	seed	VERB
admet-2684	97	8	into	into	ADP
admet-2684	97	9	96	96	NUM
admet-2684	97	10	-	-	PUNCT
admet-2684	97	11	well	well	NOUN
admet-2684	97	12	plates	plate	NOUN
admet-2684	97	13	(	(	PUNCT
admet-2684	97	14	5×104	5×104	NUM
admet-2684	97	15	cells	cell	NOUN
admet-2684	97	16	/	/	SYM
admet-2684	97	17	well	well	ADV
admet-2684	97	18	in	in	ADP
admet-2684	97	19	100	100	NUM
admet-2684	97	20	μl	μl	ADP
admet-2684	97	21	of	of	ADP
admet-2684	97	22	culture	culture	NOUN
admet-2684	97	23	medium	medium	NOUN
admet-2684	97	24	)	)	PUNCT
admet-2684	97	25	in	in	ADP
admet-2684	97	26	triplicate	triplicate	NOUN
admet-2684	97	27	in	in	ADP
admet-2684	97	28	serum	serum	NOUN
admet-2684	97	29	-	-	PUNCT
admet-2684	97	30	free	free	ADJ
admet-2684	97	31	rpmi	rpmi	NOUN
admet-2684	97	32	1640	1640	NUM
admet-2684	97	33	medium	medium	NOUN
admet-2684	97	34	and	and	CCONJ
admet-2684	97	35	measurements	measurement	NOUN
admet-2684	97	36	were	be	AUX
admet-2684	97	37	taken	take	VERB
admet-2684	97	38	24	24	NUM
admet-2684	97	39	h	h	NOUN
admet-2684	97	40	after	after	ADP
admet-2684	97	41	the	the	DET
admet-2684	97	42	treatment	treatment	NOUN
admet-2684	97	43	with	with	ADP
admet-2684	97	44	the	the	DET
admet-2684	97	45	compounds	compound	NOUN
admet-2684	97	46	.	.	PUNCT
admet-2684	98	1	the	the	DET
admet-2684	98	2	maximum	maximum	ADJ
admet-2684	98	3	concentration	concentration	NOUN
admet-2684	98	4	of	of	ADP
admet-2684	98	5	dmso	dmso	NOUN
admet-2684	98	6	(	(	PUNCT
admet-2684	98	7	sigma	sigma	PROPN
admet-2684	98	8	)	)	PUNCT
admet-2684	98	9	in	in	ADP
admet-2684	98	10	the	the	DET
admet-2684	98	11	assays	assay	NOUN
admet-2684	98	12	never	never	ADV
admet-2684	98	13	exceeded	exceed	VERB
admet-2684	98	14	0.1	0.1	NUM
admet-2684	98	15	%	%	NOUN
admet-2684	98	16	.	.	PUNCT
admet-2684	99	1	oxaliplatin	oxaliplatin	PROPN
admet-2684	99	2	and	and	CCONJ
admet-2684	99	3	camptothecin	camptothecin	PROPN
admet-2684	99	4	(	(	PUNCT
admet-2684	99	5	sigma	sigma	PROPN
admet-2684	99	6	)	)	PUNCT
admet-2684	99	7	were	be	AUX
admet-2684	99	8	used	use	VERB
admet-2684	99	9	as	as	ADP
admet-2684	99	10	reference	reference	NOUN
admet-2684	99	11	drugs	drug	NOUN
admet-2684	99	12	.	.	PUNCT
admet-2684	100	1	the	the	DET
admet-2684	100	2	median	median	ADJ
admet-2684	100	3	lethal	lethal	ADJ
admet-2684	100	4	dose	dose	NOUN
admet-2684	100	5	values	value	NOUN
admet-2684	100	6	,	,	PUNCT
admet-2684	100	7	lc50	lc50	PROPN
admet-2684	100	8	,	,	PUNCT
admet-2684	100	9	were	be	AUX
admet-2684	100	10	deduced	deduce	VERB
admet-2684	100	11	through	through	ADP
admet-2684	100	12	the	the	DET
admet-2684	100	13	production	production	NOUN
admet-2684	100	14	of	of	ADP
admet-2684	100	15	a	a	DET
admet-2684	100	16	dose	dose	NOUN
admet-2684	100	17	-	-	PUNCT
admet-2684	100	18	response	response	NOUN
admet-2684	100	19	curve	curve	NOUN
admet-2684	100	20	.	.	PUNCT
admet-2684	101	1	all	all	DET
admet-2684	101	2	data	datum	NOUN
admet-2684	101	3	from	from	ADP
admet-2684	101	4	three	three	NUM
admet-2684	101	5	independent	independent	ADJ
admet-2684	101	6	experiments	experiment	NOUN
admet-2684	101	7	were	be	AUX
admet-2684	101	8	evaluated	evaluate	VERB
admet-2684	101	9	using	use	VERB
admet-2684	101	10	graphpad	graphpad	NOUN
admet-2684	101	11	prism	prism	NOUN
admet-2684	101	12	5.00	5.00	NUM
admet-2684	101	13	software	software	NOUN
admet-2684	101	14	[	[	X
admet-2684	101	15	62	62	NUM
admet-2684	101	16	]	]	PUNCT
admet-2684	101	17	.	.	PUNCT
admet-2684	102	1	proteomic	proteomic	ADJ
admet-2684	102	2	study	study	NOUN
admet-2684	102	3	this	this	DET
admet-2684	102	4	study	study	NOUN
admet-2684	102	5	utilized	utilize	VERB
admet-2684	102	6	activity	activity	NOUN
admet-2684	102	7	-	-	PUNCT
admet-2684	102	8	based	base	VERB
admet-2684	102	9	protein	protein	NOUN
admet-2684	102	10	profiling	profiling	NOUN
admet-2684	102	11	(	(	PUNCT
admet-2684	102	12	abpp	abpp	ADJ
admet-2684	102	13	)	)	PUNCT
admet-2684	102	14	,	,	PUNCT
admet-2684	102	15	specifically	specifically	ADV
admet-2684	102	16	its	its	PRON
admet-2684	102	17	comparative	comparative	ADJ
admet-2684	102	18	technique	technique	NOUN
admet-2684	102	19	,	,	PUNCT
admet-2684	102	20	to	to	PART
admet-2684	102	21	identify	identify	VERB
admet-2684	102	22	protein	protein	NOUN
admet-2684	102	23	targets	target	NOUN
admet-2684	102	24	within	within	ADP
admet-2684	102	25	the	the	DET
admet-2684	102	26	proteome	proteome	NOUN
admet-2684	102	27	of	of	ADP
admet-2684	102	28	cell	cell	NOUN
admet-2684	102	29	lysates	lysate	NOUN
admet-2684	102	30	.	.	PUNCT
admet-2684	103	1	the	the	DET
admet-2684	103	2	experiments	experiment	NOUN
admet-2684	103	3	were	be	AUX
admet-2684	103	4	conducted	conduct	VERB
admet-2684	103	5	on	on	ADP
admet-2684	103	6	the	the	DET
admet-2684	103	7	universally	universally	ADV
admet-2684	103	8	sensitive	sensitive	ADJ
admet-2684	103	9	collection	collection	NOUN
admet-2684	103	10	strain	strain	NOUN
admet-2684	103	11	staphylococcus	staphylococcus	NOUN
admet-2684	103	12	aureus	aureus	PROPN
admet-2684	103	13	atcc	atcc	PROPN
admet-2684	103	14	29213	29213	NUM
admet-2684	103	15	and	and	CCONJ
admet-2684	103	16	mrsa	mrsa	NOUN
admet-2684	103	17	sa	sa	NOUN
admet-2684	103	18	630	630	NUM
admet-2684	103	19	isolate	isolate	VERB
admet-2684	103	20	[	[	X
admet-2684	103	21	54	54	NUM
admet-2684	103	22	]	]	PUNCT
admet-2684	103	23	.	.	PUNCT
admet-2684	104	1	both	both	DET
admet-2684	104	2	strains	strain	NOUN
admet-2684	104	3	were	be	AUX
admet-2684	104	4	treated	treat	VERB
admet-2684	104	5	as	as	ADP
admet-2684	104	6	described	describe	VERB
admet-2684	104	7	above	above	ADV
admet-2684	104	8	.	.	PUNCT
admet-2684	105	1	prior	prior	ADV
admet-2684	105	2	to	to	ADP
admet-2684	105	3	ms	ms	PROPN
admet-2684	105	4	detection	detection	NOUN
admet-2684	105	5	,	,	PUNCT
admet-2684	105	6	proteins	protein	NOUN
admet-2684	105	7	underwent	undergo	VERB
admet-2684	105	8	tryptic	tryptic	ADJ
admet-2684	105	9	digestion	digestion	NOUN
admet-2684	105	10	.	.	PUNCT
admet-2684	106	1	the	the	DET
admet-2684	106	2	bacterial	bacterial	ADJ
admet-2684	106	3	pellet	pellet	NOUN
admet-2684	106	4	was	be	AUX
admet-2684	106	5	homogenized	homogenize	VERB
admet-2684	106	6	in	in	ADP
admet-2684	106	7	a	a	DET
admet-2684	106	8	lysis	lysis	NOUN
admet-2684	106	9	buffer	buffer	NOUN
admet-2684	106	10	containing	contain	VERB
admet-2684	106	11	200	200	NUM
admet-2684	106	12	mm	mm	NOUN
admet-2684	106	13	tris	tris	NOUN
admet-2684	106	14	,	,	PUNCT
admet-2684	106	15	150	150	NUM
admet-2684	106	16	mm	mm	NOUN
admet-2684	106	17	nacl	nacl	NOUN
admet-2684	106	18	,	,	PUNCT
admet-2684	106	19	1	1	NUM
admet-2684	106	20	mm	mm	NOUN
admet-2684	106	21	ethylenediaminetetraacetic	ethylenediaminetetraacetic	ADJ
admet-2684	106	22	acid	acid	NOUN
admet-2684	106	23	(	(	PUNCT
admet-2684	106	24	edta	edta	NOUN
admet-2684	106	25	)	)	PUNCT
admet-2684	106	26	,	,	PUNCT
admet-2684	106	27	1	1	NUM
admet-2684	106	28	mm	mm	NUM
admet-2684	106	29	sodium	sodium	NOUN
admet-2684	106	30	orthovanadate	orthovanadate	ADJ
admet-2684	106	31	(	(	PUNCT
admet-2684	106	32	na₃vo₄	na₃vo₄	PROPN
admet-2684	106	33	)	)	PUNCT
admet-2684	106	34	,	,	PUNCT
admet-2684	106	35	20	20	NUM
admet-2684	106	36	mm	mm	NUM
admet-2684	106	37	sodium	sodium	NOUN
admet-2684	106	38	fluoride	fluoride	NOUN
admet-2684	106	39	(	(	PUNCT
admet-2684	106	40	naf	naf	PROPN
admet-2684	106	41	)	)	PUNCT
admet-2684	106	42	,	,	PUNCT
admet-2684	106	43	0.5	0.5	NUM
admet-2684	106	44	%	%	NOUN
admet-2684	106	45	triton	triton	PROPN
admet-2684	106	46	x-100	x-100	PROPN
admet-2684	107	1	(	(	PUNCT
admet-2684	107	2	ph	ph	NOUN
admet-2684	107	3	7.4	7.4	NUM
admet-2684	107	4	)	)	PUNCT
admet-2684	107	5	(	(	PUNCT
admet-2684	107	6	sigma	sigma	PROPN
admet-2684	107	7	)	)	PUNCT
admet-2684	107	8	,	,	PUNCT
admet-2684	107	9	and	and	CCONJ
admet-2684	107	10	a	a	DET
admet-2684	107	11	complete	complete	ADJ
admet-2684	107	12	protease	protease	NOUN
admet-2684	107	13	inhibitor	inhibitor	NOUN
admet-2684	107	14	cocktail	cocktail	NOUN
admet-2684	107	15	(	(	PUNCT
admet-2684	107	16	roche	roche	NOUN
admet-2684	107	17	)	)	PUNCT
admet-2684	107	18	.	.	PUNCT
admet-2684	108	1	protein	protein	NOUN
admet-2684	108	2	precipitation	precipitation	NOUN
admet-2684	108	3	was	be	AUX
admet-2684	108	4	carried	carry	VERB
admet-2684	108	5	out	out	ADP
admet-2684	108	6	overnight	overnight	ADV
admet-2684	108	7	using	use	VERB
admet-2684	108	8	80	80	NUM
admet-2684	108	9	%	%	NOUN
admet-2684	108	10	ice	ice	NOUN
admet-2684	108	11	-	-	PUNCT
admet-2684	108	12	cold	cold	ADJ
admet-2684	108	13	acetone	acetone	NOUN
admet-2684	108	14	(	(	PUNCT
admet-2684	108	15	sigma	sigma	PROPN
admet-2684	108	16	)	)	PUNCT
admet-2684	108	17	.	.	PUNCT
admet-2684	109	1	after	after	ADP
admet-2684	109	2	centrifugation	centrifugation	NOUN
admet-2684	109	3	,	,	PUNCT
admet-2684	109	4	the	the	DET
admet-2684	109	5	pellets	pellet	NOUN
admet-2684	109	6	were	be	AUX
admet-2684	109	7	solubilized	solubilize	VERB
admet-2684	109	8	in	in	ADP
admet-2684	109	9	8	8	NUM
admet-2684	109	10	m	m	NOUN
admet-2684	109	11	urea	urea	NOUN
admet-2684	109	12	(	(	PUNCT
admet-2684	109	13	sigma	sigma	PROPN
admet-2684	109	14	)	)	PUNCT
admet-2684	109	15	,	,	PUNCT
admet-2684	109	16	and	and	CCONJ
admet-2684	109	17	protein	protein	NOUN
admet-2684	109	18	concentrations	concentration	NOUN
admet-2684	109	19	were	be	AUX
admet-2684	109	20	determined	determine	VERB
admet-2684	109	21	using	use	VERB
admet-2684	109	22	the	the	DET
admet-2684	109	23	bio	bio	NOUN
admet-2684	109	24	-	-	ADJ
admet-2684	109	25	rad	rad	ADJ
admet-2684	109	26	protein	protein	NOUN
admet-2684	109	27	assay	assay	NOUN
admet-2684	109	28	(	(	PUNCT
admet-2684	109	29	bio	bio	NOUN
admet-2684	109	30	-	-	ADJ
admet-2684	109	31	rad	rad	PROPN
admet-2684	109	32	laboratories	laboratory	NOUN
admet-2684	109	33	,	,	PUNCT
admet-2684	109	34	colbe	colbe	NOUN
admet-2684	109	35	,	,	PUNCT
admet-2684	109	36	germany	germany	PROPN
admet-2684	109	37	)	)	PUNCT
admet-2684	109	38	.	.	PUNCT
admet-2684	110	1	a	a	DET
admet-2684	110	2	total	total	NOUN
admet-2684	110	3	of	of	ADP
admet-2684	110	4	100	100	NUM
admet-2684	110	5	μg	μg	NOUN
admet-2684	110	6	of	of	ADP
admet-2684	110	7	protein	protein	NOUN
admet-2684	110	8	was	be	AUX
admet-2684	110	9	reduced	reduce	VERB
admet-2684	110	10	with	with	ADP
admet-2684	110	11	10	10	NUM
admet-2684	110	12	mm	mm	PROPN
admet-2684	110	13	dithiothreitol	dithiothreitol	NOUN
admet-2684	110	14	(	(	PUNCT
admet-2684	110	15	sigma	sigma	PROPN
admet-2684	110	16	)	)	PUNCT
admet-2684	110	17	in	in	ADP
admet-2684	110	18	100	100	NUM
admet-2684	110	19	mm	mm	NOUN
admet-2684	110	20	ammonium	ammonium	NOUN
admet-2684	110	21	bicarbonate	bicarbonate	NOUN
admet-2684	110	22	at	at	ADP
admet-2684	110	23	37	37	NUM
admet-2684	110	24	°	°	ADP
admet-2684	110	25	c	c	NOUN
admet-2684	110	26	for	for	ADP
admet-2684	110	27	one	one	NUM
admet-2684	110	28	hour	hour	NOUN
admet-2684	110	29	.	.	PUNCT
admet-2684	111	1	alkylation	alkylation	NOUN
admet-2684	111	2	was	be	AUX
admet-2684	111	3	performed	perform	VERB
admet-2684	111	4	with	with	ADP
admet-2684	111	5	15	15	NUM
admet-2684	111	6	mm	mm	NOUN
admet-2684	111	7	iodoacetamide	iodoacetamide	NOUN
admet-2684	111	8	(	(	PUNCT
admet-2684	111	9	sigma	sigma	PROPN
admet-2684	111	10	)	)	PUNCT
admet-2684	111	11	in	in	ADP
admet-2684	111	12	100	100	NUM
admet-2684	111	13	mm	mm	NOUN
admet-2684	111	14	ammonium	ammonium	NOUN
admet-2684	111	15	bicarbonate	bicarbonate	NOUN
admet-2684	111	16	,	,	PUNCT
admet-2684	111	17	protected	protect	VERB
admet-2684	111	18	from	from	ADP
admet-2684	111	19	light	light	NOUN
admet-2684	111	20	for	for	ADP
admet-2684	111	21	30	30	NUM
admet-2684	111	22	min	min	NOUN
admet-2684	111	23	.	.	PROPN
admet-2684	111	24	trypsin	trypsin	NOUN
admet-2684	111	25	digestion	digestion	NOUN
admet-2684	111	26	(	(	PUNCT
admet-2684	111	27	promega	promega	PROPN
admet-2684	111	28	,	,	PUNCT
admet-2684	111	29	madison	madison	PROPN
admet-2684	111	30	,	,	PUNCT
admet-2684	111	31	wi	wi	PROPN
admet-2684	111	32	,	,	PUNCT
admet-2684	111	33	usa	usa	PROPN
admet-2684	111	34	)	)	PUNCT
admet-2684	111	35	was	be	AUX
admet-2684	111	36	performed	perform	VERB
admet-2684	111	37	at	at	ADP
admet-2684	111	38	an	an	DET
admet-2684	111	39	enzyme	enzyme	NOUN
admet-2684	111	40	-	-	PUNCT
admet-2684	111	41	to	to	ADP
admet-2684	111	42	-	-	PUNCT
admet-2684	111	43	substrate	substrate	NOUN
admet-2684	111	44	ratio	ratio	NOUN
admet-2684	111	45	of	of	ADP
admet-2684	111	46	1:100	1:100	NUM
admet-2684	111	47	,	,	PUNCT
admet-2684	111	48	with	with	ADP
admet-2684	111	49	overnight	overnight	ADJ
admet-2684	111	50	incubation	incubation	NOUN
admet-2684	111	51	at	at	ADP
admet-2684	111	52	37	37	NUM
admet-2684	111	53	°	°	NOUN
admet-2684	111	54	c	c	NOUN
admet-2684	111	55	.	.	PUNCT
admet-2684	112	1	admet	admet	PROPN
admet-2684	112	2	&	&	CCONJ
admet-2684	112	3	dmpk	dmpk	PROPN
admet-2684	112	4	13(2	13(2	PROPN
admet-2684	112	5	)	)	PUNCT
admet-2684	112	6	(	(	PUNCT
admet-2684	112	7	2025	2025	NUM
admet-2684	112	8	)	)	PUNCT
admet-2684	112	9	2684	2684	NUM
admet-2684	112	10	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	112	11	effect	effect	NOUN
admet-2684	112	12	of	of	ADP
admet-2684	112	13	chlorinated	chlorinate	VERB
admet-2684	112	14	1	1	NUM
admet-2684	112	15	-	-	PUNCT
admet-2684	112	16	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	112	17	-	-	PUNCT
admet-2684	112	18	carboxanilides	carboxanilide	NOUN
admet-2684	112	19	doi	doi	NOUN
admet-2684	112	20	:	:	PUNCT
admet-2684	112	21	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	112	22	5	5	NUM
admet-2684	112	23	aliquots	aliquot	NOUN
admet-2684	112	24	of	of	ADP
admet-2684	112	25	purified	purified	ADJ
admet-2684	112	26	complex	complex	ADJ
admet-2684	112	27	peptide	peptide	NOUN
admet-2684	112	28	mixtures	mixture	NOUN
admet-2684	112	29	of	of	ADP
admet-2684	112	30	100	100	NUM
admet-2684	112	31	ng	ng	NOUN
admet-2684	112	32	were	be	AUX
admet-2684	112	33	separated	separate	VERB
admet-2684	112	34	using	use	VERB
admet-2684	112	35	acquity	acquity	NOUN
admet-2684	112	36	m	m	PROPN
admet-2684	112	37	-	-	PUNCT
admet-2684	112	38	class	class	NOUN
admet-2684	112	39	uhplc	uhplc	PROPN
admet-2684	112	40	(	(	PUNCT
admet-2684	112	41	waters	water	NOUN
admet-2684	112	42	)	)	PUNCT
admet-2684	112	43	.	.	PUNCT
admet-2684	113	1	samples	sample	NOUN
admet-2684	113	2	were	be	AUX
admet-2684	113	3	loaded	load	VERB
admet-2684	113	4	onto	onto	ADP
admet-2684	113	5	the	the	DET
admet-2684	113	6	nanoease	nanoease	ADJ
admet-2684	113	7	symmetry	symmetry	NOUN
admet-2684	113	8	c18	c18	PROPN
admet-2684	113	9	trap	trap	NOUN
admet-2684	113	10	column	column	NOUN
admet-2684	113	11	(	(	PUNCT
admet-2684	113	12	25	25	NUM
admet-2684	113	13	mm	mm	NOUN
admet-2684	113	14	length	length	NOUN
admet-2684	113	15	,	,	PUNCT
admet-2684	113	16	180	180	NUM
admet-2684	113	17	μm	μm	NUM
admet-2684	113	18	diameter	diameter	NOUN
admet-2684	113	19	,	,	PUNCT
admet-2684	113	20	and	and	CCONJ
admet-2684	113	21	5	5	NUM
admet-2684	113	22	μm	μm	NOUN
admet-2684	113	23	particle	particle	NOUN
admet-2684	113	24	size	size	NOUN
admet-2684	113	25	)	)	PUNCT
admet-2684	113	26	.	.	PUNCT
admet-2684	114	1	after	after	ADP
admet-2684	114	2	2	2	NUM
admet-2684	114	3	min	min	NOUN
admet-2684	114	4	of	of	ADP
admet-2684	114	5	desalting	desalting	NOUN
admet-2684	114	6	/	/	SYM
admet-2684	114	7	concentration	concentration	NOUN
admet-2684	114	8	by	by	ADP
admet-2684	114	9	1	1	NUM
admet-2684	114	10	%	%	NOUN
admet-2684	114	11	acetonitrile	acetonitrile	NOUN
admet-2684	114	12	containing	contain	VERB
admet-2684	114	13	0.1	0.1	NUM
admet-2684	114	14	%	%	NOUN
admet-2684	114	15	formic	formic	ADJ
admet-2684	114	16	acid	acid	NOUN
admet-2684	114	17	at	at	ADP
admet-2684	114	18	a	a	DET
admet-2684	114	19	flow	flow	NOUN
admet-2684	114	20	rate	rate	NOUN
admet-2684	114	21	of	of	ADP
admet-2684	114	22	8	8	NUM
admet-2684	114	23	μl	μl	PRON
admet-2684	114	24	/	/	SYM
admet-2684	114	25	min	min	NOUN
admet-2684	114	26	,	,	PUNCT
admet-2684	114	27	peptides	peptide	NOUN
admet-2684	114	28	were	be	AUX
admet-2684	114	29	introduced	introduce	VERB
admet-2684	114	30	to	to	ADP
admet-2684	114	31	the	the	DET
admet-2684	114	32	nanoease	nanoease	ADJ
admet-2684	114	33	hss	hss	NOUN
admet-2684	114	34	t3	t3	PROPN
admet-2684	114	35	c18	c18	PROPN
admet-2684	114	36	analytical	analytical	ADJ
admet-2684	114	37	column	column	NOUN
admet-2684	114	38	(	(	PUNCT
admet-2684	114	39	100	100	NUM
admet-2684	114	40	mm	mm	NOUN
admet-2684	114	41	length	length	NOUN
admet-2684	114	42	,	,	PUNCT
admet-2684	114	43	75	75	NUM
admet-2684	114	44	μm	μm	NUM
admet-2684	114	45	diameter	diameter	NOUN
admet-2684	114	46	,	,	PUNCT
admet-2684	114	47	and	and	CCONJ
admet-2684	114	48	1.8	1.8	NUM
admet-2684	114	49	μm	μm	NOUN
admet-2684	114	50	particle	particle	NOUN
admet-2684	114	51	size	size	NOUN
admet-2684	114	52	)	)	PUNCT
admet-2684	114	53	.	.	PUNCT
admet-2684	115	1	for	for	ADP
admet-2684	115	2	the	the	DET
admet-2684	115	3	thorough	thorough	ADJ
admet-2684	115	4	separation	separation	NOUN
admet-2684	115	5	,	,	PUNCT
admet-2684	115	6	a	a	DET
admet-2684	115	7	90	90	NUM
admet-2684	115	8	min	min	NOUN
admet-2684	115	9	gradient	gradient	NOUN
admet-2684	115	10	of	of	ADP
admet-2684	115	11	5	5	NUM
admet-2684	115	12	to	to	PART
admet-2684	115	13	35	35	NUM
admet-2684	115	14	%	%	NOUN
admet-2684	115	15	acetonitrile	acetonitrile	NOUN
admet-2684	115	16	with	with	ADP
admet-2684	115	17	0.1	0.1	NUM
admet-2684	115	18	%	%	NOUN
admet-2684	115	19	formic	formic	ADJ
admet-2684	115	20	acid	acid	NOUN
admet-2684	115	21	was	be	AUX
admet-2684	115	22	applied	apply	VERB
admet-2684	115	23	at	at	ADP
admet-2684	115	24	a	a	DET
admet-2684	115	25	flow	flow	NOUN
admet-2684	115	26	rate	rate	NOUN
admet-2684	115	27	of	of	ADP
admet-2684	115	28	300	300	NUM
admet-2684	115	29	nl	nl	PROPN
admet-2684	115	30	/	/	SYM
admet-2684	115	31	min	min	PROPN
admet-2684	115	32	.	.	PUNCT
admet-2684	116	1	the	the	DET
admet-2684	116	2	samples	sample	NOUN
admet-2684	116	3	were	be	AUX
admet-2684	116	4	sprayed	spray	VERB
admet-2684	116	5	(	(	PUNCT
admet-2684	116	6	3.1	3.1	NUM
admet-2684	116	7	kv	kv	PROPN
admet-2684	116	8	capillary	capillary	ADJ
admet-2684	116	9	voltage	voltage	NOUN
admet-2684	116	10	)	)	PUNCT
admet-2684	116	11	to	to	ADP
admet-2684	116	12	the	the	DET
admet-2684	116	13	quadrupole	quadrupole	NOUN
admet-2684	116	14	time	time	NOUN
admet-2684	116	15	-	-	PUNCT
admet-2684	116	16	of	of	ADP
admet-2684	116	17	-	-	PUNCT
admet-2684	116	18	flight	flight	NOUN
admet-2684	116	19	mass	mass	NOUN
admet-2684	116	20	spectrometer	spectrometer	NOUN
admet-2684	116	21	synapt	synapt	NOUN
admet-2684	116	22	g2	g2	PROPN
admet-2684	116	23	-	-	PUNCT
admet-2684	116	24	si	si	PROPN
admet-2684	116	25	(	(	PUNCT
admet-2684	116	26	waters	water	NOUN
admet-2684	116	27	)	)	PUNCT
admet-2684	116	28	with	with	ADP
admet-2684	116	29	an	an	DET
admet-2684	116	30	ion	ion	NOUN
admet-2684	116	31	mobility	mobility	NOUN
admet-2684	116	32	option	option	NOUN
admet-2684	116	33	.	.	PUNCT
admet-2684	117	1	spectra	spectra	PROPN
admet-2684	117	2	were	be	AUX
admet-2684	117	3	recorded	record	VERB
admet-2684	117	4	in	in	ADP
admet-2684	117	5	a	a	DET
admet-2684	117	6	data	data	NOUN
admet-2684	117	7	-	-	PUNCT
admet-2684	117	8	independent	independent	ADJ
admet-2684	117	9	manner	manner	NOUN
admet-2684	117	10	in	in	ADP
admet-2684	117	11	high	high	ADJ
admet-2684	117	12	-	-	PUNCT
admet-2684	117	13	definition	definition	NOUN
admet-2684	117	14	mse	mse	NOUN
admet-2684	117	15	mode	mode	PROPN
admet-2684	117	16	.	.	PUNCT
admet-2684	118	1	ions	ion	NOUN
admet-2684	118	2	with	with	ADP
admet-2684	118	3	50	50	NUM
admet-2684	118	4	to	to	PART
admet-2684	118	5	2000	2000	NUM
admet-2684	118	6	m	m	NOUN
admet-2684	118	7	/	/	SYM
admet-2684	118	8	z	z	PROPN
admet-2684	118	9	were	be	AUX
admet-2684	118	10	detected	detect	VERB
admet-2684	118	11	in	in	ADP
admet-2684	118	12	both	both	DET
admet-2684	118	13	channels	channel	NOUN
admet-2684	118	14	,	,	PUNCT
admet-2684	118	15	with	with	ADP
admet-2684	118	16	a	a	DET
admet-2684	118	17	1	1	NUM
admet-2684	118	18	s	s	NOUN
admet-2684	118	19	spectral	spectral	ADJ
admet-2684	118	20	acquisition	acquisition	NOUN
admet-2684	118	21	scan	scan	NOUN
admet-2684	118	22	rate	rate	NOUN
admet-2684	118	23	.	.	PUNCT
admet-2684	119	1	peak	peak	NOUN
admet-2684	119	2	detection	detection	NOUN
admet-2684	119	3	and	and	CCONJ
admet-2684	119	4	processing	processing	NOUN
admet-2684	119	5	were	be	AUX
admet-2684	119	6	executed	execute	VERB
admet-2684	119	7	using	use	VERB
admet-2684	119	8	progenesis	progenesis	NOUN
admet-2684	119	9	qi	qi	PROPN
admet-2684	119	10	4.0	4.0	NUM
admet-2684	119	11	software	software	NOUN
admet-2684	119	12	[	[	X
admet-2684	119	13	63	63	NUM
admet-2684	119	14	]	]	PUNCT
admet-2684	119	15	(	(	PUNCT
admet-2684	119	16	waters	water	NOUN
admet-2684	119	17	)	)	PUNCT
admet-2684	119	18	.	.	PUNCT
admet-2684	120	1	for	for	ADP
admet-2684	120	2	peak	peak	NOUN
admet-2684	120	3	picking	picking	NOUN
admet-2684	120	4	,	,	PUNCT
admet-2684	120	5	the	the	DET
admet-2684	120	6	following	follow	VERB
admet-2684	120	7	thresholds	threshold	NOUN
admet-2684	120	8	were	be	AUX
admet-2684	120	9	applied	apply	VERB
admet-2684	120	10	:	:	PUNCT
admet-2684	120	11	low	low	ADJ
admet-2684	120	12	-	-	PUNCT
admet-2684	120	13	energy	energy	NOUN
admet-2684	120	14	320	320	NUM
admet-2684	120	15	counts	count	NOUN
admet-2684	120	16	and	and	CCONJ
admet-2684	120	17	high	high	ADJ
admet-2684	120	18	-	-	PUNCT
admet-2684	120	19	energy	energy	NOUN
admet-2684	120	20	40	40	NUM
admet-2684	120	21	counts	count	NOUN
admet-2684	120	22	.	.	PUNCT
admet-2684	121	1	precursors	precursor	NOUN
admet-2684	121	2	and	and	CCONJ
admet-2684	121	3	fragment	fragment	ADJ
admet-2684	121	4	ions	ion	NOUN
admet-2684	121	5	were	be	AUX
admet-2684	121	6	coupled	couple	VERB
admet-2684	121	7	using	use	VERB
admet-2684	121	8	correlations	correlation	NOUN
admet-2684	121	9	of	of	ADP
admet-2684	121	10	chromatographic	chromatographic	ADJ
admet-2684	121	11	elution	elution	NOUN
admet-2684	121	12	profiles	profile	NOUN
admet-2684	121	13	in	in	ADP
admet-2684	121	14	low	low	ADJ
admet-2684	121	15	/	/	SYM
admet-2684	121	16	high	high	ADJ
admet-2684	121	17	-	-	PUNCT
admet-2684	121	18	energy	energy	NOUN
admet-2684	121	19	traces	trace	NOUN
admet-2684	121	20	.	.	PUNCT
admet-2684	122	1	then	then	ADV
admet-2684	122	2	,	,	PUNCT
admet-2684	122	3	peak	peak	NOUN
admet-2684	122	4	retention	retention	NOUN
admet-2684	122	5	times	time	NOUN
admet-2684	122	6	were	be	AUX
admet-2684	122	7	aligned	align	VERB
admet-2684	122	8	across	across	ADP
admet-2684	122	9	all	all	DET
admet-2684	122	10	chromatograms	chromatogram	NOUN
admet-2684	122	11	.	.	PUNCT
admet-2684	123	1	peak	peak	NOUN
admet-2684	123	2	intensities	intensity	NOUN
admet-2684	123	3	were	be	AUX
admet-2684	123	4	normalized	normalize	VERB
admet-2684	123	5	to	to	ADP
admet-2684	123	6	the	the	DET
admet-2684	123	7	median	median	ADJ
admet-2684	123	8	distribution	distribution	NOUN
admet-2684	123	9	of	of	ADP
admet-2684	123	10	all	all	DET
admet-2684	123	11	ions	ion	NOUN
admet-2684	123	12	,	,	PUNCT
admet-2684	123	13	assuming	assume	VERB
admet-2684	123	14	that	that	SCONJ
admet-2684	123	15	most	most	ADJ
admet-2684	123	16	signals	signal	NOUN
admet-2684	123	17	were	be	AUX
admet-2684	123	18	unaffected	unaffected	ADJ
admet-2684	123	19	by	by	ADP
admet-2684	123	20	the	the	DET
admet-2684	123	21	experimental	experimental	ADJ
admet-2684	123	22	conditions	condition	NOUN
admet-2684	123	23	.	.	PUNCT
admet-2684	124	1	protein	protein	NOUN
admet-2684	124	2	identification	identification	NOUN
admet-2684	124	3	was	be	AUX
admet-2684	124	4	performed	perform	VERB
admet-2684	124	5	in	in	ADP
admet-2684	124	6	progenesis	progenesis	NOUN
admet-2684	124	7	qi	qi	PROPN
admet-2684	124	8	4.0	4.0	NUM
admet-2684	124	9	[	[	SYM
admet-2684	124	10	63	63	NUM
admet-2684	124	11	]	]	PUNCT
admet-2684	124	12	utilizing	utilize	VERB
admet-2684	124	13	the	the	DET
admet-2684	124	14	staphylococcus	staphylococcus	NOUN
admet-2684	124	15	aureus	aureus	PROPN
admet-2684	124	16	uniprot	uniprot	PROPN
admet-2684	124	17	database	database	NOUN
admet-2684	125	1	[	[	X
admet-2684	125	2	64	64	NUM
admet-2684	125	3	]	]	PUNCT
admet-2684	125	4	.	.	PUNCT
admet-2684	126	1	results	result	NOUN
admet-2684	126	2	and	and	CCONJ
admet-2684	126	3	discussion	discussion	NOUN
admet-2684	126	4	chemistry	chemistry	NOUN
admet-2684	126	5	and	and	CCONJ
admet-2684	126	6	computational	computational	ADJ
admet-2684	126	7	adme	adme	NOUN
admet-2684	126	8	properties	property	NOUN
admet-2684	126	9	the	the	DET
admet-2684	126	10	synthesis	synthesis	NOUN
admet-2684	126	11	of	of	ADP
admet-2684	126	12	the	the	DET
admet-2684	126	13	target	target	NOUN
admet-2684	126	14	anilides	anilide	NOUN
admet-2684	126	15	(	(	PUNCT
admet-2684	126	16	see	see	VERB
admet-2684	126	17	scheme	scheme	NOUN
admet-2684	126	18	1	1	NUM
admet-2684	126	19	)	)	PUNCT
admet-2684	126	20	was	be	AUX
admet-2684	126	21	performed	perform	VERB
admet-2684	126	22	by	by	ADP
admet-2684	126	23	click	click	VERB
admet-2684	126	24	chemistry	chemistry	NOUN
admet-2684	126	25	realized	realize	VERB
admet-2684	126	26	in	in	ADP
admet-2684	126	27	a	a	DET
admet-2684	126	28	microwave	microwave	NOUN
admet-2684	126	29	reactor	reactor	NOUN
admet-2684	126	30	using	use	VERB
admet-2684	126	31	phosphorus	phosphorus	NOUN
admet-2684	126	32	chloride	chloride	NOUN
admet-2684	126	33	in	in	ADP
admet-2684	126	34	dry	dry	ADJ
admet-2684	126	35	chlorobenzene	chlorobenzene	NOUN
admet-2684	126	36	from	from	ADP
admet-2684	126	37	starting	start	VERB
admet-2684	126	38	materials	material	NOUN
admet-2684	126	39	.	.	PUNCT
admet-2684	127	1	1	1	NUM
admet-2684	127	2	-	-	PUNCT
admet-2684	127	3	hydroxynaphthalene-2carboxylic	hydroxynaphthalene-2carboxylic	NOUN
admet-2684	127	4	acid	acid	NOUN
admet-2684	127	5	and	and	CCONJ
admet-2684	127	6	a	a	DET
admet-2684	127	7	suitable	suitable	ADJ
admet-2684	127	8	aniline	aniline	NOUN
admet-2684	127	9	as	as	SCONJ
admet-2684	127	10	described	describe	VERB
admet-2684	127	11	in	in	ADP
admet-2684	127	12	gonec	gonec	PROPN
admet-2684	127	13	et	et	PROPN
admet-2684	127	14	al	al	PROPN
admet-2684	127	15	.	.	PUNCT
admet-2684	128	1	[	[	X
admet-2684	128	2	29	29	NUM
admet-2684	128	3	]	]	PUNCT
admet-2684	128	4	for	for	ADP
admet-2684	128	5	1	1	NUM
admet-2684	128	6	-	-	SYM
admet-2684	128	7	4	4	NUM
admet-2684	128	8	or	or	CCONJ
admet-2684	128	9	gonec	gonec	PROPN
admet-2684	128	10	et	et	PROPN
admet-2684	128	11	al	al	PROPN
admet-2684	128	12	.	.	PUNCT
admet-2684	129	1	[	[	X
admet-2684	129	2	52	52	NUM
admet-2684	129	3	]	]	PUNCT
admet-2684	129	4	for	for	ADP
admet-2684	129	5	5	5	NUM
admet-2684	129	6	-	-	SYM
admet-2684	129	7	13	13	NUM
admet-2684	129	8	.	.	PUNCT
admet-2684	130	1	scheme	scheme	NOUN
admet-2684	130	2	1	1	NUM
admet-2684	130	3	.	.	PUNCT
admet-2684	130	4	synthesis	synthesis	NOUN
admet-2684	130	5	of	of	ADP
admet-2684	130	6	ring	ring	NOUN
admet-2684	130	7	-	-	PUNCT
admet-2684	130	8	substituted	substitute	VERB
admet-2684	130	9	1	1	NUM
admet-2684	130	10	-	-	PUNCT
admet-2684	130	11	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	130	12	-	-	PUNCT
admet-2684	130	13	carboxanilides	carboxanilide	NOUN
admet-2684	130	14	1	1	NUM
admet-2684	130	15	-	-	SYM
admet-2684	130	16	13	13	NUM
admet-2684	130	17	.	.	PUNCT
admet-2684	130	18	reagents	reagent	NOUN
admet-2684	130	19	and	and	CCONJ
admet-2684	130	20	conditions	condition	NOUN
admet-2684	130	21	:	:	PUNCT
admet-2684	130	22	(	(	PUNCT
admet-2684	130	23	a	a	X
admet-2684	130	24	)	)	PUNCT
admet-2684	130	25	pcl3	pcl3	NOUN
admet-2684	130	26	,	,	PUNCT
admet-2684	130	27	chlorobenzene	chlorobenzene	NOUN
admet-2684	130	28	,	,	PUNCT
admet-2684	130	29	microwave	microwave	NOUN
admet-2684	130	30	synthesis	synthesis	NOUN
admet-2684	130	31	(	(	PUNCT
admet-2684	130	32	500	500	NUM
admet-2684	130	33	w	w	NOUN
admet-2684	130	34	,	,	PUNCT
admet-2684	130	35	130	130	NUM
admet-2684	130	36	°	°	NOUN
admet-2684	130	37	c	c	NOUN
admet-2684	130	38	,	,	PUNCT
admet-2684	130	39	15	15	NUM
admet-2684	130	40	min	min	NOUN
admet-2684	130	41	)	)	PUNCT
admet-2684	130	42	.	.	PUNCT
admet-2684	131	1	all	all	DET
admet-2684	131	2	the	the	DET
admet-2684	131	3	compounds	compound	NOUN
admet-2684	131	4	are	be	AUX
admet-2684	131	5	mentioned	mention	VERB
admet-2684	131	6	in	in	ADP
admet-2684	131	7	table	table	NOUN
admet-2684	131	8	1	1	NUM
admet-2684	131	9	,	,	PUNCT
admet-2684	131	10	where	where	SCONJ
admet-2684	131	11	their	their	PRON
admet-2684	131	12	physicochemical	physicochemical	ADJ
admet-2684	131	13	properties	property	NOUN
admet-2684	131	14	are	be	AUX
admet-2684	131	15	also	also	ADV
admet-2684	131	16	listed	list	VERB
admet-2684	131	17	as	as	ADP
admet-2684	131	18	key	key	ADJ
admet-2684	131	19	parameters	parameter	NOUN
admet-2684	131	20	for	for	ADP
admet-2684	131	21	their	their	PRON
admet-2684	131	22	drug	drug	NOUN
admet-2684	131	23	-	-	PUNCT
admet-2684	131	24	likeness	likeness	NOUN
admet-2684	131	25	[	[	X
admet-2684	131	26	65	65	NUM
admet-2684	131	27	]	]	PUNCT
admet-2684	131	28	.	.	PUNCT
admet-2684	132	1	their	their	PRON
admet-2684	132	2	lipophilicity	lipophilicity	NOUN
admet-2684	132	3	was	be	AUX
admet-2684	132	4	measured	measure	VERB
admet-2684	132	5	experimentally	experimentally	ADV
admet-2684	132	6	(	(	PUNCT
admet-2684	132	7	expressed	express	VERB
admet-2684	132	8	as	as	ADP
admet-2684	132	9	the	the	DET
admet-2684	132	10	logarithm	logarithm	NOUN
admet-2684	132	11	of	of	ADP
admet-2684	132	12	the	the	DET
admet-2684	132	13	capacity	capacity	NOUN
admet-2684	132	14	factor	factor	NOUN
admet-2684	132	15	k	k	PROPN
admet-2684	132	16	and	and	CCONJ
admet-2684	132	17	the	the	DET
admet-2684	132	18	logarithms	logarithm	NOUN
admet-2684	132	19	of	of	ADP
admet-2684	132	20	the	the	DET
admet-2684	132	21	distribution	distribution	NOUN
admet-2684	132	22	coefficients	coefficient	NOUN
admet-2684	132	23	dph	dph	X
admet-2684	132	24	at	at	ADP
admet-2684	132	25	ph	ph	PROPN
admet-2684	132	26	6.5	6.5	NUM
admet-2684	132	27	and	and	CCONJ
admet-2684	132	28	7.4	7.4	NUM
admet-2684	132	29	)	)	PUNCT
admet-2684	132	30	,	,	PUNCT
admet-2684	132	31	and	and	CCONJ
admet-2684	132	32	log	log	VERB
admet-2684	132	33	p	p	NOUN
admet-2684	132	34	was	be	AUX
admet-2684	132	35	predicted	predict	VERB
admet-2684	132	36	using	use	VERB
admet-2684	132	37	the	the	DET
admet-2684	132	38	commercially	commercially	ADV
admet-2684	132	39	available	available	ADJ
admet-2684	132	40	acd	acd	PROPN
admet-2684	132	41	/	/	SYM
admet-2684	132	42	percepta	percepta	PROPN
admet-2684	132	43	ver	ver	NOUN
admet-2684	132	44	.	.	PUNCT
admet-2684	133	1	2012	2012	NUM
admet-2684	133	2	program	program	NOUN
admet-2684	133	3	[	[	X
admet-2684	133	4	66	66	NUM
admet-2684	133	5	]	]	PUNCT
admet-2684	133	6	.	.	PUNCT
admet-2684	134	1	lipinski	lipinski	PROPN
admet-2684	134	2	's	's	PART
admet-2684	134	3	rule	rule	NOUN
admet-2684	134	4	of	of	ADP
admet-2684	134	5	five	five	NUM
admet-2684	134	6	(	(	PUNCT
admet-2684	134	7	ro5	ro5	ADJ
admet-2684	134	8	)	)	PUNCT
admet-2684	134	9	parameters	parameter	NOUN
admet-2684	134	10	[	[	X
admet-2684	134	11	67,68	67,68	NUM
admet-2684	134	12	]	]	PUNCT
admet-2684	134	13	were	be	AUX
admet-2684	134	14	also	also	ADV
admet-2684	134	15	calculated	calculate	VERB
admet-2684	134	16	using	use	VERB
admet-2684	134	17	this	this	DET
admet-2684	134	18	software	software	NOUN
admet-2684	134	19	,	,	PUNCT
admet-2684	134	20	and	and	CCONJ
admet-2684	134	21	information	information	NOUN
admet-2684	134	22	about	about	ADP
admet-2684	134	23	compounds	compound	NOUN
admet-2684	134	24	related	relate	VERB
admet-2684	134	25	to	to	ADP
admet-2684	134	26	the	the	DET
admet-2684	134	27	veber	veber	PROPN
admet-2684	134	28	rule	rule	NOUN
admet-2684	134	29	was	be	AUX
admet-2684	134	30	also	also	ADV
admet-2684	134	31	added	add	VERB
admet-2684	134	32	to	to	PART
admet-2684	134	33	clarify	clarify	VERB
admet-2684	134	34	whether	whether	SCONJ
admet-2684	134	35	the	the	DET
admet-2684	134	36	compounds	compound	NOUN
admet-2684	134	37	should	should	AUX
admet-2684	134	38	have	have	VERB
admet-2684	134	39	good	good	ADJ
admet-2684	134	40	oral	oral	ADJ
admet-2684	134	41	bioavailability	bioavailability	NOUN
admet-2684	134	42	[	[	X
admet-2684	134	43	68,69	68,69	NOUN
admet-2684	134	44	]	]	PUNCT
admet-2684	134	45	.	.	PUNCT
admet-2684	135	1	in	in	ADP
admet-2684	135	2	addition	addition	NOUN
admet-2684	135	3	to	to	ADP
admet-2684	135	4	the	the	DET
admet-2684	135	5	parameters	parameter	NOUN
admet-2684	135	6	characterizing	characterize	VERB
admet-2684	135	7	adme	adme	NOUN
admet-2684	135	8	,	,	PUNCT
admet-2684	135	9	table	table	NOUN
admet-2684	135	10	1	1	NUM
admet-2684	135	11	includes	include	VERB
admet-2684	135	12	the	the	DET
admet-2684	135	13	electronic	electronic	ADJ
admet-2684	135	14	σ(ar	σ(ar	NOUN
admet-2684	135	15	)	)	PUNCT
admet-2684	135	16	parameters	parameter	NOUN
admet-2684	135	17	of	of	ADP
admet-2684	135	18	the	the	DET
admet-2684	135	19	entire	entire	ADJ
admet-2684	135	20	substituted	substitute	VERB
admet-2684	135	21	anilide	anilide	NOUN
admet-2684	135	22	ring	ring	NOUN
admet-2684	135	23	,	,	PUNCT
admet-2684	135	24	characterizing	characterize	VERB
admet-2684	135	25	the	the	DET
admet-2684	135	26	ability	ability	NOUN
admet-2684	135	27	to	to	PART
admet-2684	135	28	withdraw	withdraw	VERB
admet-2684	135	29	or	or	CCONJ
admet-2684	135	30	donate	donate	VERB
admet-2684	135	31	electrons	electron	NOUN
admet-2684	135	32	to	to	ADP
admet-2684	135	33	the	the	DET
admet-2684	135	34	molecular	molecular	ADJ
admet-2684	135	35	system	system	NOUN
admet-2684	135	36	.	.	PUNCT
admet-2684	136	1	the	the	DET
admet-2684	136	2	values	value	NOUN
admet-2684	136	3	of	of	ADP
admet-2684	136	4	σ(ar	σ(ar	NOUN
admet-2684	136	5	)	)	PUNCT
admet-2684	136	6	are	be	AUX
admet-2684	136	7	found	find	VERB
admet-2684	136	8	in	in	ADP
admet-2684	136	9	a	a	DET
admet-2684	136	10	wide	wide	ADJ
admet-2684	136	11	range	range	NOUN
admet-2684	136	12	from	from	ADP
admet-2684	136	13	0.60	0.60	NUM
admet-2684	136	14	(	(	PUNCT
admet-2684	136	15	unsubstituted	unsubstituted	ADJ
admet-2684	136	16	derivative	derivative	ADJ
admet-2684	136	17	1	1	NUM
admet-2684	136	18	)	)	PUNCT
admet-2684	136	19	to	to	ADP
admet-2684	136	20	1.56	1.56	NUM
admet-2684	136	21	(	(	PUNCT
admet-2684	136	22	compound	compound	NOUN
admet-2684	136	23	11	11	NUM
admet-2684	136	24	,	,	PUNCT
admet-2684	136	25	r	r	NOUN
admet-2684	136	26	=	=	SYM
admet-2684	136	27	2,4,5	2,4,5	NUM
admet-2684	136	28	-	-	PUNCT
admet-2684	136	29	cl	cl	NOUN
admet-2684	136	30	)	)	PUNCT
admet-2684	136	31	.	.	PUNCT
admet-2684	137	1	although	although	SCONJ
admet-2684	137	2	this	this	PRON
admet-2684	137	3	is	be	AUX
admet-2684	137	4	a	a	DET
admet-2684	137	5	small	small	ADJ
admet-2684	137	6	series	series	NOUN
admet-2684	137	7	of	of	ADP
admet-2684	137	8	compounds	compound	NOUN
admet-2684	137	9	,	,	PUNCT
admet-2684	137	10	it	it	PRON
admet-2684	137	11	is	be	AUX
admet-2684	137	12	a	a	DET
admet-2684	137	13	compact	compact	ADJ
admet-2684	137	14	and	and	CCONJ
admet-2684	137	15	coherent	coherent	ADJ
admet-2684	137	16	series	series	NOUN
admet-2684	137	17	,	,	PUNCT
admet-2684	137	18	and	and	CCONJ
admet-2684	137	19	interesting	interesting	ADJ
admet-2684	137	20	observations	observation	NOUN
admet-2684	137	21	can	can	AUX
admet-2684	137	22	be	be	AUX
admet-2684	137	23	made	make	VERB
admet-2684	137	24	due	due	ADJ
admet-2684	137	25	to	to	ADP
admet-2684	137	26	the	the	DET
admet-2684	137	27	variability	variability	NOUN
admet-2684	137	28	of	of	ADP
admet-2684	137	29	the	the	DET
admet-2684	137	30	substitution	substitution	NOUN
admet-2684	137	31	positions	position	NOUN
admet-2684	137	32	in	in	ADP
admet-2684	137	33	the	the	DET
admet-2684	137	34	anilide	anilide	ADJ
admet-2684	137	35	part	part	NOUN
admet-2684	137	36	of	of	ADP
admet-2684	137	37	the	the	DET
admet-2684	137	38	molecule	molecule	NOUN
admet-2684	137	39	.	.	PUNCT
admet-2684	138	1	the	the	DET
admet-2684	138	2	graphs	graph	NOUN
admet-2684	138	3	in	in	ADP
admet-2684	138	4	figure	figure	NOUN
admet-2684	138	5	1	1	NUM
admet-2684	138	6	show	show	VERB
admet-2684	138	7	the	the	DET
admet-2684	138	8	correlation	correlation	NOUN
admet-2684	138	9	between	between	ADP
admet-2684	138	10	the	the	DET
admet-2684	138	11	experimental	experimental	ADJ
admet-2684	138	12	and	and	CCONJ
admet-2684	138	13	calculated	calculate	VERB
admet-2684	138	14	lipophilicity	lipophilicity	NOUN
admet-2684	138	15	values	value	NOUN
admet-2684	138	16	.	.	PUNCT
admet-2684	139	1	as	as	SCONJ
admet-2684	139	2	can	can	AUX
admet-2684	139	3	be	be	AUX
admet-2684	139	4	seen	see	VERB
admet-2684	139	5	from	from	ADP
admet-2684	139	6	the	the	DET
admet-2684	139	7	values	value	NOUN
admet-2684	139	8	of	of	ADP
admet-2684	139	9	the	the	DET
admet-2684	139	10	correlation	correlation	NOUN
admet-2684	139	11	coefficients	coefficient	VERB
admet-2684	139	12	r	r	NOUN
admet-2684	139	13	,	,	PUNCT
admet-2684	139	14	which	which	PRON
admet-2684	139	15	are	be	AUX
admet-2684	139	16	in	in	ADP
admet-2684	139	17	the	the	DET
admet-2684	139	18	interval	interval	NOUN
admet-2684	139	19	0.26	0.26	NUM
admet-2684	139	20	-	-	SYM
admet-2684	139	21	0.46	0.46	NUM
admet-2684	139	22	(	(	PUNCT
admet-2684	139	23	n	n	NOUN
admet-2684	139	24	=	=	SYM
admet-2684	139	25	13	13	NUM
admet-2684	139	26	)	)	PUNCT
admet-2684	139	27	,	,	PUNCT
admet-2684	139	28	these	these	PRON
admet-2684	139	29	are	be	AUX
admet-2684	139	30	very	very	ADV
admet-2684	139	31	poor	poor	ADJ
admet-2684	139	32	agreements	agreement	NOUN
admet-2684	139	33	.	.	PUNCT
admet-2684	140	1	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	PROPN
admet-2684	141	1	l.	l.	PROPN
admet-2684	141	2	vrablova	vrablova	PROPN
admet-2684	141	3	et	et	PROPN
admet-2684	141	4	al	al	PROPN
admet-2684	141	5	.	.	PROPN
admet-2684	141	6	admet	admet	PROPN
admet-2684	141	7	&	&	CCONJ
admet-2684	141	8	dmpk	dmpk	PROPN
admet-2684	141	9	13(2	13(2	PROPN
admet-2684	141	10	)	)	PUNCT
admet-2684	141	11	(	(	PUNCT
admet-2684	141	12	2025	2025	NUM
admet-2684	141	13	)	)	PUNCT
admet-2684	141	14	2684	2684	NUM
admet-2684	141	15	6	6	NUM
admet-2684	141	16	table	table	NOUN
admet-2684	141	17	1	1	NUM
admet-2684	141	18	.	.	PUNCT
admet-2684	141	19	structure	structure	NOUN
admet-2684	141	20	of	of	ADP
admet-2684	141	21	1	1	NUM
admet-2684	141	22	-	-	PUNCT
admet-2684	141	23	hydroxynaphthalene-1	hydroxynaphthalene-1	NOUN
admet-2684	141	24	-	-	PUNCT
admet-2684	141	25	carboxanilides	carboxanilide	NOUN
admet-2684	141	26	1	1	NUM
admet-2684	141	27	-	-	SYM
admet-2684	141	28	13	13	NUM
admet-2684	141	29	;	;	PUNCT
admet-2684	141	30	experimentally	experimentally	ADV
admet-2684	141	31	determined	determine	VERB
admet-2684	141	32	log	log	NOUN
admet-2684	141	33	k	k	NOUN
admet-2684	141	34	,	,	PUNCT
admet-2684	141	35	log	log	PROPN
admet-2684	141	36	d6.5	d6.5	PROPN
admet-2684	141	37	,	,	PUNCT
admet-2684	141	38	log	log	VERB
admet-2684	141	39	d7.4	d7.4	NOUN
admet-2684	141	40	values	value	NOUN
admet-2684	141	41	and	and	CCONJ
admet-2684	141	42	predicted	predict	VERB
admet-2684	141	43	lipophilicity	lipophilicity	NOUN
admet-2684	141	44	(	(	PUNCT
admet-2684	141	45	log	log	VERB
admet-2684	141	46	p	p	NOUN
admet-2684	141	47	)	)	PUNCT
admet-2684	141	48	values	value	NOUN
admet-2684	141	49	,	,	PUNCT
admet-2684	141	50	their	their	PRON
admet-2684	141	51	molecular	molecular	ADJ
admet-2684	141	52	weight	weight	NOUN
admet-2684	141	53	(	(	PUNCT
admet-2684	141	54	mw	mw	NOUN
admet-2684	141	55	)	)	PUNCT
admet-2684	141	56	,	,	PUNCT
admet-2684	141	57	number	number	NOUN
admet-2684	141	58	of	of	ADP
admet-2684	141	59	h	h	NOUN
admet-2684	141	60	-	-	PUNCT
admet-2684	141	61	bond	bond	NOUN
admet-2684	141	62	donors	donor	NOUN
admet-2684	141	63	(	(	PUNCT
admet-2684	141	64	hbd	hbd	PROPN
admet-2684	141	65	)	)	PUNCT
admet-2684	141	66	,	,	PUNCT
admet-2684	141	67	number	number	NOUN
admet-2684	141	68	of	of	ADP
admet-2684	141	69	h	h	NOUN
admet-2684	141	70	-	-	PUNCT
admet-2684	141	71	bond	bond	NOUN
admet-2684	141	72	acceptors	acceptor	NOUN
admet-2684	141	73	(	(	PUNCT
admet-2684	141	74	hba	hba	NOUN
admet-2684	141	75	)	)	PUNCT
admet-2684	141	76	,	,	PUNCT
admet-2684	141	77	number	number	NOUN
admet-2684	141	78	of	of	ADP
admet-2684	141	79	rotatable	rotatable	ADJ
admet-2684	141	80	bonds	bond	NOUN
admet-2684	141	81	(	(	PUNCT
admet-2684	141	82	rb	rb	NOUN
admet-2684	141	83	)	)	PUNCT
admet-2684	141	84	,	,	PUNCT
admet-2684	141	85	topological	topological	ADJ
admet-2684	141	86	polar	polar	ADJ
admet-2684	141	87	surface	surface	NOUN
admet-2684	141	88	area	area	NOUN
admet-2684	141	89	(	(	PUNCT
admet-2684	141	90	tpsa	tpsa	PROPN
admet-2684	141	91	)	)	PUNCT
admet-2684	141	92	,	,	PUNCT
admet-2684	141	93	and	and	CCONJ
admet-2684	141	94	electronic	electronic	ADJ
admet-2684	141	95	σ(ar	σ(ar	NOUN
admet-2684	141	96	)	)	PUNCT
admet-2684	141	97	parameters	parameter	NOUN
admet-2684	141	98	of	of	ADP
admet-2684	141	99	anilide	anilide	NOUN
admet-2684	141	100	ring	ring	NOUN
admet-2684	141	101	of	of	ADP
admet-2684	141	102	investigated	investigate	VERB
admet-2684	141	103	compounds	compound	NOUN
admet-2684	141	104	comp	comp	NOUN
admet-2684	141	105	.	.	PUNCT
admet-2684	142	1	r	r	NOUN
admet-2684	142	2	log	log	NOUN
admet-2684	142	3	k	k	PROPN
admet-2684	142	4	log	log	PROPN
admet-2684	142	5	d6.5	d6.5	VERB
admet-2684	142	6	log	log	NOUN
admet-2684	142	7	d7.4	d7.4	NOUN
admet-2684	142	8	log	log	NOUN
admet-2684	142	9	pa	pa	PROPN
admet-2684	142	10	mwa	mwa	PROPN
admet-2684	142	11	hbda	hbda	VERB
admet-2684	142	12	hbaa	hbaa	PROPN
admet-2684	142	13	rba	rba	PROPN
admet-2684	142	14	tpsaa	tpsaa	PROPN
admet-2684	142	15	,	,	PUNCT
admet-2684	142	16	nm2	nm2	NOUN
admet-2684	142	17	σ(ar	σ(ar	NOUN
admet-2684	142	18	)	)	PUNCT
admet-2684	142	19	a	a	DET
admet-2684	142	20	1	1	NUM
admet-2684	142	21	h	h	NOUN
admet-2684	142	22	0.6084	0.6084	NUM
admet-2684	142	23	0.5139	0.5139	NUM
admet-2684	142	24	0.5487	0.5487	NUM
admet-2684	142	25	4.52	4.52	NUM
admet-2684	142	26	263.29	263.29	NUM
admet-2684	142	27	2	2	NUM
admet-2684	142	28	3	3	NUM
admet-2684	142	29	2	2	NUM
admet-2684	142	30	0.49	0.49	NUM
admet-2684	142	31	0.60	0.60	NUM
admet-2684	142	32	2	2	NUM
admet-2684	142	33	2	2	NUM
admet-2684	142	34	-	-	PUNCT
admet-2684	142	35	cl	cl	NOUN
admet-2684	142	36	0.6900	0.6900	NUM
admet-2684	142	37	0.5828	0.5828	NUM
admet-2684	142	38	0.5836	0.5836	NUM
admet-2684	142	39	5.02	5.02	NUM
admet-2684	142	40	297.74	297.74	NUM
admet-2684	142	41	2	2	NUM
admet-2684	142	42	3	3	NUM
admet-2684	142	43	2	2	NUM
admet-2684	142	44	0.49	0.49	NUM
admet-2684	142	45	1.05	1.05	NUM
admet-2684	142	46	3	3	NUM
admet-2684	142	47	3	3	NUM
admet-2684	142	48	-	-	PUNCT
admet-2684	142	49	cl	cl	NOUN
admet-2684	142	50	0.8556	0.8556	NUM
admet-2684	142	51	0.7362	0.7362	NUM
admet-2684	142	52	0.7227	0.7227	NUM
admet-2684	142	53	5.25	5.25	NUM
admet-2684	142	54	297.74	297.74	NUM
admet-2684	142	55	2	2	NUM
admet-2684	142	56	3	3	NUM
admet-2684	142	57	2	2	NUM
admet-2684	142	58	0.49	0.49	NUM
admet-2684	142	59	0.85	0.85	NUM
admet-2684	142	60	4	4	NUM
admet-2684	142	61	4	4	NUM
admet-2684	142	62	-	-	PUNCT
admet-2684	142	63	cl	cl	NOUN
admet-2684	142	64	0.8880	0.8880	NUM
admet-2684	142	65	0.7640	0.7640	NUM
admet-2684	142	66	0.7501	0.7501	NUM
admet-2684	142	67	5.24	5.24	NUM
admet-2684	142	68	297.74	297.74	NUM
admet-2684	142	69	2	2	NUM
admet-2684	142	70	3	3	NUM
admet-2684	142	71	2	2	NUM
admet-2684	142	72	0.49	0.49	NUM
admet-2684	142	73	0.75	0.75	NUM
admet-2684	142	74	5	5	NUM
admet-2684	142	75	2,3	2,3	NUM
admet-2684	142	76	-	-	NOUN
admet-2684	142	77	cl	cl	NOUN
admet-2684	142	78	0.6838	0.6838	NUM
admet-2684	142	79	0.4371	0.4371	NUM
admet-2684	142	80	0.3870	0.3870	NUM
admet-2684	142	81	5.76	5.76	NUM
admet-2684	142	82	332.18	332.18	NUM
admet-2684	142	83	2	2	NUM
admet-2684	142	84	3	3	NUM
admet-2684	142	85	2	2	NUM
admet-2684	142	86	0.49	0.49	NUM
admet-2684	142	87	1.22	1.22	NUM
admet-2684	142	88	6	6	NUM
admet-2684	142	89	2,4	2,4	NUM
admet-2684	142	90	-	-	PUNCT
admet-2684	142	91	cl	cl	NOUN
admet-2684	142	92	0.7387	0.7387	NUM
admet-2684	142	93	0.5168	0.5168	NUM
admet-2684	142	94	0.4680	0.4680	NUM
admet-2684	142	95	5.78	5.78	NUM
admet-2684	142	96	332.18	332.18	NUM
admet-2684	142	97	2	2	NUM
admet-2684	142	98	3	3	NUM
admet-2684	142	99	2	2	NUM
admet-2684	142	100	0.49	0.49	NUM
admet-2684	142	101	1.12	1.12	NUM
admet-2684	142	102	7	7	NUM
admet-2684	142	103	2,5	2,5	NUM
admet-2684	142	104	-	-	PUNCT
admet-2684	142	105	cl	cl	NOUN
admet-2684	142	106	0.6717	0.6717	NUM
admet-2684	142	107	0.3949	0.3949	NUM
admet-2684	142	108	0.3938	0.3938	NUM
admet-2684	142	109	5.82	5.82	NUM
admet-2684	142	110	332.18	332.18	NUM
admet-2684	142	111	2	2	NUM
admet-2684	142	112	3	3	NUM
admet-2684	142	113	2	2	NUM
admet-2684	142	114	0.49	0.49	NUM
admet-2684	142	115	1.22	1.22	NUM
admet-2684	142	116	8	8	NUM
admet-2684	142	117	2,6	2,6	NUM
admet-2684	142	118	-	-	NOUN
admet-2684	142	119	cl	cl	NOUN
admet-2684	142	120	0.5729	0.5729	NUM
admet-2684	142	121	0.4516	0.4516	NUM
admet-2684	142	122	0.4594	0.4594	NUM
admet-2684	142	123	5.52	5.52	NUM
admet-2684	142	124	332.18	332.18	NUM
admet-2684	142	125	2	2	NUM
admet-2684	142	126	3	3	NUM
admet-2684	142	127	2	2	NUM
admet-2684	142	128	0.49	0.49	NUM
admet-2684	142	129	1.33	1.33	NUM
admet-2684	142	130	9	9	NUM
admet-2684	142	131	3,4	3,4	NUM
admet-2684	142	132	-	-	PUNCT
admet-2684	142	133	cl	cl	NOUN
admet-2684	142	134	0.9304	0.9304	NUM
admet-2684	142	135	0.9048	0.9048	NUM
admet-2684	142	136	0.8909	0.8909	NUM
admet-2684	142	137	5.99	5.99	NUM
admet-2684	142	138	332.18	332.18	NUM
admet-2684	142	139	2	2	NUM
admet-2684	142	140	3	3	NUM
admet-2684	142	141	2	2	NUM
admet-2684	142	142	0.49	0.49	NUM
admet-2684	142	143	1.19	1.19	NUM
admet-2684	142	144	10	10	NUM
admet-2684	142	145	3,5	3,5	NUM
admet-2684	142	146	-	-	PUNCT
admet-2684	142	147	cl	cl	NOUN
admet-2684	142	148	0.9704	0.9704	NUM
admet-2684	142	149	0.9531	0.9531	NUM
admet-2684	143	1	0.9306	0.9306	NUM
admet-2684	143	2	6.01	6.01	NUM
admet-2684	143	3	332.18	332.18	NUM
admet-2684	143	4	2	2	NUM
admet-2684	143	5	3	3	NUM
admet-2684	143	6	2	2	NUM
admet-2684	143	7	0.49	0.49	NUM
admet-2684	143	8	1.11	1.11	NUM
admet-2684	143	9	11	11	NUM
admet-2684	143	10	2,4,5	2,4,5	NUM
admet-2684	143	11	-	-	PUNCT
admet-2684	143	12	cl	cl	NOUN
admet-2684	143	13	0.6894	0.6894	NUM
admet-2684	143	14	0.5314	0.5314	NUM
admet-2684	143	15	0.4864	0.4864	NUM
admet-2684	144	1	6.31	6.31	NUM
admet-2684	144	2	366.62	366.62	NUM
admet-2684	144	3	2	2	NUM
admet-2684	144	4	3	3	NUM
admet-2684	144	5	2	2	NUM
admet-2684	144	6	0.49	0.49	NUM
admet-2684	144	7	1.56	1.56	NUM
admet-2684	144	8	12	12	NUM
admet-2684	144	9	2,4,6	2,4,6	NUM
admet-2684	144	10	-	-	PUNCT
admet-2684	144	11	cl	cl	NOUN
admet-2684	144	12	0.8398	0.8398	NUM
admet-2684	144	13	0.7254	0.7254	NUM
admet-2684	144	14	0.6825	0.6825	NUM
admet-2684	144	15	6.15	6.15	NUM
admet-2684	144	16	366.62	366.62	NUM
admet-2684	144	17	2	2	NUM
admet-2684	144	18	3	3	NUM
admet-2684	144	19	2	2	NUM
admet-2684	144	20	0.49	0.49	NUM
admet-2684	144	21	1.48	1.48	NUM
admet-2684	144	22	13	13	NUM
admet-2684	144	23	3,4,5	3,4,5	NUM
admet-2684	144	24	-	-	NOUN
admet-2684	144	25	cl	cl	NOUN
admet-2684	144	26	1.2387	1.2387	NUM
admet-2684	144	27	1.0960	1.0960	NUM
admet-2684	144	28	1.0561	1.0561	NUM
admet-2684	144	29	6.28	6.28	NUM
admet-2684	144	30	366.62	366.62	NUM
admet-2684	144	31	2	2	NUM
admet-2684	144	32	3	3	NUM
admet-2684	144	33	2	2	NUM
admet-2684	144	34	0.49	0.49	NUM
admet-2684	144	35	1.46	1.46	NUM
admet-2684	144	36	ro5	ro5	ADJ
admet-2684	144	37	<	<	X
admet-2684	144	38	5	5	NUM
admet-2684	144	39	<	<	X
admet-2684	144	40	500	500	NUM
admet-2684	144	41	<	<	X
admet-2684	144	42	5	5	NUM
admet-2684	144	43	<	<	SYM
admet-2684	144	44	10	10	NUM
admet-2684	144	45	veber	veber	PROPN
admet-2684	144	46	rule	rule	NOUN
admet-2684	144	47	<	<	X
admet-2684	144	48	10	10	NUM
admet-2684	144	49	<	<	NOUN
admet-2684	144	50	1.40	1.40	NUM
admet-2684	144	51	aacd	aacd	NOUN
admet-2684	144	52	/	/	SYM
admet-2684	144	53	percepta	percepta	PROPN
admet-2684	144	54	ver	ver	NOUN
admet-2684	144	55	.	.	PUNCT
admet-2684	144	56	2012	2012	NUM
admet-2684	144	57	(	(	PUNCT
admet-2684	144	58	advanced	advanced	ADJ
admet-2684	144	59	chemistry	chemistry	NOUN
admet-2684	144	60	development	development	NOUN
admet-2684	144	61	.	.	PUNCT
admet-2684	144	62	inc	inc	PROPN
admet-2684	144	63	.	.	PROPN
admet-2684	144	64	,	,	PUNCT
admet-2684	144	65	toronto	toronto	PROPN
admet-2684	144	66	,	,	PUNCT
admet-2684	144	67	on	on	ADP
admet-2684	144	68	,	,	PUNCT
admet-2684	144	69	canada	canada	PROPN
admet-2684	144	70	,	,	PUNCT
admet-2684	144	71	2012	2012	NUM
admet-2684	144	72	)	)	PUNCT
admet-2684	145	1	[	[	X
admet-2684	145	2	66	66	NUM
admet-2684	145	3	]	]	PUNCT
admet-2684	145	4	;	;	PUNCT
admet-2684	145	5	ro5	ro5	PROPN
admet-2684	145	6	=	=	SYM
admet-2684	145	7	lipinski	lipinski	PROPN
admet-2684	145	8	’s	’s	PART
admet-2684	145	9	rule	rule	NOUN
admet-2684	145	10	of	of	ADP
admet-2684	145	11	five	five	NUM
admet-2684	145	12	.	.	PUNCT
admet-2684	146	1	the	the	DET
admet-2684	146	2	highest	high	ADJ
admet-2684	146	3	correlation	correlation	NOUN
admet-2684	146	4	was	be	AUX
admet-2684	146	5	achieved	achieve	VERB
admet-2684	146	6	for	for	ADP
admet-2684	146	7	the	the	DET
admet-2684	146	8	comparison	comparison	NOUN
admet-2684	146	9	of	of	ADP
admet-2684	146	10	log	log	PROPN
admet-2684	146	11	k	k	PROPN
admet-2684	146	12	versus	versus	ADP
admet-2684	146	13	log	log	PROPN
admet-2684	146	14	p	p	X
admet-2684	146	15	,	,	PUNCT
admet-2684	146	16	i.e.	i.e.	X
admet-2684	146	17	for	for	ADP
admet-2684	146	18	measurements	measurement	NOUN
admet-2684	146	19	in	in	ADP
admet-2684	146	20	water	water	NOUN
admet-2684	146	21	.	.	PUNCT
admet-2684	147	1	at	at	ADP
admet-2684	147	2	physiological	physiological	ADJ
admet-2684	147	3	ph	ph	NOUN
admet-2684	147	4	7.4	7.4	NUM
admet-2684	147	5	(	(	PUNCT
admet-2684	147	6	i.e.	i.e.	X
admet-2684	147	7	slightly	slightly	ADV
admet-2684	147	8	basic	basic	ADJ
admet-2684	147	9	)	)	PUNCT
admet-2684	147	10	,	,	PUNCT
admet-2684	147	11	the	the	DET
admet-2684	147	12	correlation	correlation	NOUN
admet-2684	147	13	is	be	AUX
admet-2684	147	14	extremely	extremely	ADV
admet-2684	147	15	low	low	ADJ
admet-2684	147	16	,	,	PUNCT
admet-2684	147	17	indicating	indicate	VERB
admet-2684	147	18	the	the	DET
admet-2684	147	19	probable	probable	ADJ
admet-2684	147	20	role	role	NOUN
admet-2684	147	21	of	of	ADP
admet-2684	147	22	the	the	DET
admet-2684	147	23	free	free	ADJ
admet-2684	147	24	phenol	phenol	NOUN
admet-2684	147	25	group	group	NOUN
admet-2684	147	26	in	in	ADP
admet-2684	147	27	position	position	NOUN
admet-2684	147	28	1	1	NUM
admet-2684	147	29	of	of	ADP
admet-2684	147	30	the	the	DET
admet-2684	147	31	naphthalene	naphthalene	NOUN
admet-2684	147	32	scaffold	scaffold	NOUN
admet-2684	147	33	and	and	CCONJ
admet-2684	147	34	strong	strong	ADJ
admet-2684	147	35	interand	interand	VERB
admet-2684	147	36	intramolecular	intramolecular	ADJ
admet-2684	147	37	interactions	interaction	NOUN
admet-2684	147	38	in	in	ADP
admet-2684	147	39	the	the	DET
admet-2684	147	40	aqueous	aqueous	ADJ
admet-2684	147	41	environment	environment	NOUN
admet-2684	147	42	,	,	PUNCT
admet-2684	147	43	which	which	PRON
admet-2684	147	44	are	be	AUX
admet-2684	147	45	imperceptible	imperceptible	ADJ
admet-2684	147	46	using	use	VERB
admet-2684	147	47	the	the	DET
admet-2684	147	48	software	software	NOUN
admet-2684	147	49	but	but	CCONJ
admet-2684	147	50	are	be	AUX
admet-2684	147	51	essential	essential	ADJ
admet-2684	147	52	for	for	ADP
admet-2684	147	53	the	the	DET
admet-2684	147	54	behavior	behavior	NOUN
admet-2684	147	55	of	of	ADP
admet-2684	147	56	this	this	DET
admet-2684	147	57	type	type	NOUN
admet-2684	147	58	of	of	ADP
admet-2684	147	59	compounds	compound	NOUN
admet-2684	147	60	in	in	ADP
admet-2684	147	61	a	a	DET
admet-2684	147	62	biological	biological	ADJ
admet-2684	147	63	system	system	NOUN
admet-2684	147	64	.	.	PUNCT
admet-2684	148	1	comparison	comparison	NOUN
admet-2684	148	2	of	of	ADP
admet-2684	148	3	experimental	experimental	ADJ
admet-2684	148	4	log	log	PROPN
admet-2684	148	5	k	k	PROPN
admet-2684	148	6	versus	versus	ADP
admet-2684	148	7	log	log	PROPN
admet-2684	148	8	d	d	NOUN
admet-2684	148	9	values	value	NOUN
admet-2684	148	10	(	(	PUNCT
admet-2684	148	11	figure	figure	NOUN
admet-2684	148	12	2	2	NUM
admet-2684	148	13	)	)	PUNCT
admet-2684	148	14	yielded	yield	VERB
admet-2684	148	15	good	good	ADJ
admet-2684	148	16	correlations	correlation	NOUN
admet-2684	148	17	(	(	PUNCT
admet-2684	148	18	r	r	NOUN
admet-2684	148	19	ranging	range	VERB
admet-2684	148	20	from	from	ADP
admet-2684	148	21	0.91	0.91	NUM
admet-2684	148	22	to	to	ADP
admet-2684	148	23	0.99	0.99	NUM
admet-2684	148	24	,	,	PUNCT
admet-2684	148	25	n	n	NOUN
admet-2684	148	26	=	=	NOUN
admet-2684	148	27	13	13	NUM
admet-2684	148	28	)	)	PUNCT
admet-2684	148	29	.	.	PUNCT
admet-2684	149	1	figure	figure	NOUN
admet-2684	149	2	1	1	NUM
admet-2684	149	3	.	.	PUNCT
admet-2684	149	4	comparison	comparison	NOUN
admet-2684	149	5	of	of	ADP
admet-2684	149	6	experimentally	experimentally	ADV
admet-2684	149	7	determined	determine	VERB
admet-2684	149	8	values	value	NOUN
admet-2684	149	9	of	of	ADP
admet-2684	149	10	log	log	NOUN
admet-2684	150	1	k	k	PROPN
admet-2684	150	2	(	(	PUNCT
admet-2684	150	3	a	a	NOUN
admet-2684	150	4	)	)	PUNCT
admet-2684	150	5	,	,	PUNCT
admet-2684	150	6	log	log	VERB
admet-2684	150	7	d6.5	d6.5	PROPN
admet-2684	150	8	(	(	PUNCT
admet-2684	150	9	b	b	NOUN
admet-2684	150	10	)	)	PUNCT
admet-2684	150	11	,	,	PUNCT
admet-2684	150	12	and	and	CCONJ
admet-2684	150	13	log	log	VERB
admet-2684	150	14	d7.4	d7.4	PROPN
admet-2684	150	15	(	(	PUNCT
admet-2684	150	16	c	c	NOUN
admet-2684	150	17	)	)	PUNCT
admet-2684	150	18	with	with	ADP
admet-2684	150	19	calculated	calculate	VERB
admet-2684	150	20	log	log	PROPN
admet-2684	150	21	p	p	PROPN
admet-2684	150	22	(	(	PUNCT
admet-2684	150	23	acd	acd	NOUN
admet-2684	150	24	/	/	SYM
admet-2684	150	25	percepta	percepta	NOUN
admet-2684	151	1	[	[	X
admet-2684	151	2	66	66	NUM
admet-2684	151	3	]	]	PUNCT
admet-2684	151	4	)	)	PUNCT
admet-2684	151	5	of	of	ADP
admet-2684	151	6	carboxanilides	carboxanilide	NOUN
admet-2684	151	7	1	1	NUM
admet-2684	151	8	-	-	SYM
admet-2684	151	9	13	13	NUM
admet-2684	151	10	figure	figure	NOUN
admet-2684	151	11	3	3	NUM
admet-2684	151	12	shows	show	VERB
admet-2684	151	13	the	the	DET
admet-2684	151	14	order	order	NOUN
admet-2684	151	15	of	of	ADP
admet-2684	151	16	compounds	compound	NOUN
admet-2684	151	17	according	accord	VERB
admet-2684	151	18	to	to	ADP
admet-2684	151	19	increasing	increase	VERB
admet-2684	151	20	log	log	NOUN
admet-2684	151	21	k	k	PROPN
admet-2684	151	22	values	value	NOUN
admet-2684	151	23	.	.	PUNCT
admet-2684	152	1	the	the	DET
admet-2684	152	2	height	height	NOUN
admet-2684	152	3	of	of	ADP
admet-2684	152	4	the	the	DET
admet-2684	152	5	bars	bar	NOUN
admet-2684	152	6	indicates	indicate	VERB
admet-2684	152	7	that	that	SCONJ
admet-2684	152	8	log	log	NOUN
admet-2684	152	9	k	k	PROPN
admet-2684	152	10	values	value	NOUN
admet-2684	152	11	are	be	AUX
admet-2684	152	12	the	the	DET
admet-2684	152	13	highest	high	ADJ
admet-2684	152	14	compared	compare	VERB
admet-2684	152	15	to	to	PART
admet-2684	152	16	log	log	VERB
admet-2684	152	17	d	d	NOUN
admet-2684	152	18	values	value	NOUN
admet-2684	152	19	,	,	PUNCT
admet-2684	152	20	with	with	ADP
admet-2684	152	21	the	the	DET
admet-2684	152	22	lowest	low	ADJ
admet-2684	152	23	lipophilicity	lipophilicity	NOUN
admet-2684	152	24	values	value	NOUN
admet-2684	152	25	being	be	AUX
admet-2684	152	26	achieved	achieve	VERB
admet-2684	152	27	when	when	SCONJ
admet-2684	152	28	measured	measure	VERB
admet-2684	152	29	at	at	ADP
admet-2684	152	30	ph	ph	PROPN
admet-2684	152	31	7.4	7.4	NUM
admet-2684	152	32	.	.	PUNCT
admet-2684	152	33	0.2	0.2	NUM
admet-2684	152	34	0.4	0.4	NUM
admet-2684	152	35	0.6	0.6	NUM
admet-2684	152	36	0.8	0.8	NUM
admet-2684	152	37	1.0	1.0	NUM
admet-2684	152	38	1.2	1.2	NUM
admet-2684	152	39	1.4	1.4	NUM
admet-2684	152	40	4.0	4.0	NUM
admet-2684	152	41	4.5	4.5	NUM
admet-2684	152	42	5.0	5.0	NUM
admet-2684	152	43	5.5	5.5	NUM
admet-2684	152	44	6.0	6.0	NUM
admet-2684	152	45	6.5	6.5	NUM
admet-2684	152	46	lo	lo	NOUN
admet-2684	152	47	g	g	PROPN
admet-2684	152	48	k	k	PROPN
admet-2684	152	49	log	log	VERB
admet-2684	152	50	p	p	NOUN
admet-2684	152	51	r	r	NOUN
admet-2684	152	52	=	=	PUNCT
admet-2684	152	53	0.4678	0.4678	NUM
admet-2684	152	54	a	a	DET
admet-2684	152	55	0.2	0.2	NUM
admet-2684	152	56	0.4	0.4	NUM
admet-2684	152	57	0.6	0.6	NUM
admet-2684	152	58	0.8	0.8	NUM
admet-2684	152	59	1.0	1.0	NUM
admet-2684	152	60	1.2	1.2	NUM
admet-2684	152	61	1.4	1.4	NUM
admet-2684	152	62	4.0	4.0	NUM
admet-2684	152	63	4.5	4.5	NUM
admet-2684	152	64	5.0	5.0	NUM
admet-2684	152	65	5.5	5.5	NUM
admet-2684	152	66	6.0	6.0	NUM
admet-2684	152	67	6.5	6.5	NUM
admet-2684	152	68	lo	lo	NOUN
admet-2684	152	69	g	g	PROPN
admet-2684	152	70	d	d	PROPN
admet-2684	152	71	6	6	NUM
admet-2684	152	72	.	.	SYM
admet-2684	152	73	5	5	NUM
admet-2684	152	74	log	log	NOUN
admet-2684	152	75	p	p	NOUN
admet-2684	152	76	r	r	NOUN
admet-2684	152	77	=	=	SYM
admet-2684	152	78	0.3477	0.3477	NUM
admet-2684	152	79	b	b	NOUN
admet-2684	152	80	0.2	0.2	NUM
admet-2684	152	81	0.4	0.4	NUM
admet-2684	152	82	0.6	0.6	NUM
admet-2684	152	83	0.8	0.8	NUM
admet-2684	152	84	1.0	1.0	NUM
admet-2684	152	85	1.2	1.2	NUM
admet-2684	152	86	1.4	1.4	NUM
admet-2684	152	87	4.0	4.0	NUM
admet-2684	152	88	4.5	4.5	NUM
admet-2684	152	89	5.0	5.0	NUM
admet-2684	152	90	5.5	5.5	NUM
admet-2684	152	91	6.0	6.0	NUM
admet-2684	152	92	6.5	6.5	NUM
admet-2684	152	93	lo	lo	NOUN
admet-2684	152	94	g	g	PROPN
admet-2684	152	95	d	d	PROPN
admet-2684	152	96	7	7	NUM
admet-2684	152	97	.	.	SYM
admet-2684	152	98	4	4	NUM
admet-2684	152	99	log	log	NOUN
admet-2684	152	100	p	p	NOUN
admet-2684	152	101	r	r	NOUN
admet-2684	152	102	=	=	NOUN
admet-2684	152	103	0.2625	0.2625	NUM
admet-2684	152	104	c	c	X
admet-2684	152	105	admet	admet	PROPN
admet-2684	152	106	&	&	CCONJ
admet-2684	152	107	dmpk	dmpk	PROPN
admet-2684	152	108	13(2	13(2	PROPN
admet-2684	152	109	)	)	PUNCT
admet-2684	152	110	(	(	PUNCT
admet-2684	152	111	2025	2025	NUM
admet-2684	152	112	)	)	PUNCT
admet-2684	152	113	2684	2684	NUM
admet-2684	152	114	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	152	115	effect	effect	NOUN
admet-2684	152	116	of	of	ADP
admet-2684	152	117	chlorinated	chlorinate	VERB
admet-2684	152	118	1	1	NUM
admet-2684	152	119	-	-	PUNCT
admet-2684	152	120	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	152	121	-	-	PUNCT
admet-2684	152	122	carboxanilides	carboxanilide	NOUN
admet-2684	152	123	doi	doi	NOUN
admet-2684	152	124	:	:	PUNCT
admet-2684	152	125	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	152	126	7	7	NUM
admet-2684	152	127	figure	figure	NOUN
admet-2684	152	128	2	2	NUM
admet-2684	152	129	.	.	PUNCT
admet-2684	152	130	cross	cros	NOUN
admet-2684	152	131	-	-	NOUN
admet-2684	152	132	correlations	correlation	NOUN
admet-2684	152	133	of	of	ADP
admet-2684	152	134	experimentally	experimentally	ADV
admet-2684	152	135	determined	determine	VERB
admet-2684	152	136	values	value	NOUN
admet-2684	152	137	of	of	ADP
admet-2684	152	138	log	log	PROPN
admet-2684	152	139	k	k	PROPN
admet-2684	152	140	versus	versus	X
admet-2684	152	141	log	log	PROPN
admet-2684	152	142	d6.5	d6.5	PROPN
admet-2684	152	143	(	(	PUNCT
admet-2684	152	144	a	a	NOUN
admet-2684	152	145	)	)	PUNCT
admet-2684	152	146	,	,	PUNCT
admet-2684	152	147	log	log	PROPN
admet-2684	152	148	k	k	PROPN
admet-2684	152	149	versus	versus	X
admet-2684	152	150	log	log	PROPN
admet-2684	152	151	d7.4	d7.4	PROPN
admet-2684	152	152	(	(	PUNCT
admet-2684	152	153	b	b	NOUN
admet-2684	152	154	)	)	PUNCT
admet-2684	152	155	and	and	CCONJ
admet-2684	152	156	log	log	VERB
admet-2684	152	157	d6.5	d6.5	PROPN
admet-2684	152	158	versus	versus	ADP
admet-2684	152	159	log	log	NOUN
admet-2684	152	160	d7.4	d7.4	PROPN
admet-2684	152	161	(	(	PUNCT
admet-2684	152	162	c	c	NOUN
admet-2684	152	163	)	)	PUNCT
admet-2684	152	164	of	of	ADP
admet-2684	152	165	carboxanilides	carboxanilide	NOUN
admet-2684	152	166	1	1	NUM
admet-2684	152	167	-	-	SYM
admet-2684	152	168	13	13	NUM
admet-2684	152	169	however	however	ADV
admet-2684	152	170	,	,	PUNCT
admet-2684	152	171	measurements	measurement	NOUN
admet-2684	152	172	in	in	ADP
admet-2684	152	173	all	all	DET
admet-2684	152	174	three	three	NUM
admet-2684	152	175	types	type	NOUN
admet-2684	152	176	of	of	ADP
admet-2684	152	177	media	medium	NOUN
admet-2684	152	178	confirm	confirm	VERB
admet-2684	152	179	that	that	SCONJ
admet-2684	152	180	,	,	PUNCT
admet-2684	152	181	surprisingly	surprisingly	ADV
admet-2684	152	182	,	,	PUNCT
admet-2684	152	183	the	the	DET
admet-2684	152	184	unsubstituted	unsubstituted	ADJ
admet-2684	152	185	derivative	derivative	ADJ
admet-2684	152	186	1	1	NUM
admet-2684	152	187	is	be	AUX
admet-2684	152	188	not	not	PART
admet-2684	152	189	the	the	PRON
admet-2684	152	190	least	least	ADJ
admet-2684	152	191	lipophilic	lipophilic	ADJ
admet-2684	152	192	compound	compound	NOUN
admet-2684	152	193	of	of	ADP
admet-2684	152	194	the	the	DET
admet-2684	152	195	discussed	discuss	VERB
admet-2684	152	196	series	series	NOUN
admet-2684	152	197	,	,	PUNCT
admet-2684	152	198	but	but	CCONJ
admet-2684	152	199	n-(2,6	n-(2,6	PROPN
admet-2684	152	200	-	-	PUNCT
admet-2684	152	201	dichlorophenyl)-1	dichlorophenyl)-1	PROPN
admet-2684	152	202	-	-	PUNCT
admet-2684	152	203	hydroxynaphthalene-2	hydroxynaphthalene-2	NOUN
admet-2684	152	204	-	-	PUNCT
admet-2684	152	205	carboxamide	carboxamide	NOUN
admet-2684	152	206	(	(	PUNCT
admet-2684	152	207	8)	8)	NUM
admet-2684	152	208	.	.	PUNCT
admet-2684	153	1	the	the	DET
admet-2684	153	2	most	most	ADV
admet-2684	153	3	lipophilic	lipophilic	NOUN
admet-2684	153	4	is	be	AUX
admet-2684	153	5	n-(3,4,5	n-(3,4,5	NOUN
admet-2684	153	6	-	-	PUNCT
admet-2684	153	7	trichlorophenyl)-1	trichlorophenyl)-1	NUM
admet-2684	153	8	-	-	PUNCT
admet-2684	153	9	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	153	10	-carboxamide	-carboxamide	NOUN
admet-2684	153	11	(	(	PUNCT
admet-2684	153	12	13	13	NUM
admet-2684	153	13	)	)	PUNCT
admet-2684	153	14	,	,	PUNCT
admet-2684	153	15	with	with	ADP
admet-2684	153	16	a	a	DET
admet-2684	153	17	large	large	ADJ
admet-2684	153	18	jump	jump	NOUN
admet-2684	153	19	from	from	ADP
admet-2684	153	20	all	all	DET
admet-2684	153	21	other	other	ADJ
admet-2684	153	22	derivatives	derivative	NOUN
admet-2684	153	23	.	.	PUNCT
admet-2684	154	1	it	it	PRON
admet-2684	154	2	is	be	AUX
admet-2684	154	3	clear	clear	ADJ
admet-2684	154	4	from	from	ADP
admet-2684	154	5	the	the	DET
admet-2684	154	6	graph	graph	NOUN
admet-2684	154	7	that	that	DET
admet-2684	154	8	substitution	substitution	NOUN
admet-2684	154	9	in	in	ADP
admet-2684	154	10	ortho	ortho	PROPN
admet-2684	154	11	positions	position	NOUN
admet-2684	154	12	significantly	significantly	ADV
admet-2684	154	13	reduces	reduce	VERB
admet-2684	154	14	lipophilicity	lipophilicity	NOUN
admet-2684	154	15	,	,	PUNCT
admet-2684	154	16	while	while	SCONJ
admet-2684	154	17	substitution	substitution	NOUN
admet-2684	154	18	mainly	mainly	ADV
admet-2684	154	19	in	in	ADP
admet-2684	154	20	meta	meta	ADJ
admet-2684	154	21	positions	position	NOUN
admet-2684	154	22	increases	increase	VERB
admet-2684	154	23	it	it	PRON
admet-2684	154	24	.	.	PUNCT
admet-2684	155	1	compound	compound	VERB
admet-2684	155	2	◼	◼	NUM
admet-2684	155	3	log	log	NOUN
admet-2684	155	4	k	k	PROPN
admet-2684	155	5	◼	◼	NUM
admet-2684	155	6	log	log	PROPN
admet-2684	155	7	d6.5	d6.5	PROPN
admet-2684	155	8	◼	◼	NUM
admet-2684	155	9	log	log	NOUN
admet-2684	155	10	d7.4	d7.4	NOUN
admet-2684	155	11	figure	figure	NOUN
admet-2684	155	12	3	3	NUM
admet-2684	155	13	.	.	PUNCT
admet-2684	156	1	order	order	NOUN
admet-2684	156	2	of	of	ADP
admet-2684	156	3	individual	individual	ADJ
admet-2684	156	4	derivatives	derivative	NOUN
admet-2684	156	5	arranged	arrange	VERB
admet-2684	156	6	according	accord	VERB
admet-2684	156	7	to	to	ADP
admet-2684	156	8	increasing	increase	VERB
admet-2684	156	9	log	log	NOUN
admet-2684	156	10	k	k	PROPN
admet-2684	156	11	values	value	NOUN
admet-2684	156	12	regarding	regard	VERB
admet-2684	156	13	the	the	DET
admet-2684	156	14	calculated	calculate	VERB
admet-2684	156	15	adme	adme	NOUN
admet-2684	156	16	parameters	parameter	NOUN
admet-2684	156	17	listed	list	VERB
admet-2684	156	18	in	in	ADP
admet-2684	156	19	table	table	NOUN
admet-2684	156	20	1	1	NUM
admet-2684	156	21	,	,	PUNCT
admet-2684	156	22	lipinski	lipinski	PROPN
admet-2684	156	23	's	's	PART
admet-2684	156	24	recommendation	recommendation	NOUN
admet-2684	156	25	of	of	ADP
admet-2684	156	26	molecular	molecular	ADJ
admet-2684	156	27	weight	weight	NOUN
admet-2684	156	28	<	<	X
admet-2684	156	29	500	500	NUM
admet-2684	156	30	is	be	AUX
admet-2684	156	31	met	meet	VERB
admet-2684	156	32	by	by	ADP
admet-2684	156	33	all	all	DET
admet-2684	156	34	compounds	compound	NOUN
admet-2684	156	35	.	.	PUNCT
admet-2684	157	1	on	on	ADP
admet-2684	157	2	the	the	DET
admet-2684	157	3	contrary	contrary	NOUN
admet-2684	157	4	,	,	PUNCT
admet-2684	157	5	their	their	PRON
admet-2684	157	6	lipophilicity	lipophilicity	NOUN
admet-2684	157	7	,	,	PUNCT
admet-2684	157	8	which	which	PRON
admet-2684	157	9	is	be	AUX
admet-2684	157	10	higher	high	ADJ
admet-2684	157	11	than	than	ADP
admet-2684	157	12	the	the	DET
admet-2684	157	13	recommended	recommend	VERB
admet-2684	157	14	log	log	NOUN
admet-2684	157	15	p	p	NOUN
admet-2684	157	16	<	<	X
admet-2684	157	17	5	5	NUM
admet-2684	157	18	for	for	ADP
admet-2684	157	19	all	all	DET
admet-2684	157	20	molecules	molecule	NOUN
admet-2684	157	21	,	,	PUNCT
admet-2684	157	22	is	be	AUX
admet-2684	157	23	contradictory	contradictory	ADJ
admet-2684	157	24	.	.	PUNCT
admet-2684	158	1	all	all	DET
admet-2684	158	2	other	other	ADJ
admet-2684	158	3	parameters	parameter	NOUN
admet-2684	158	4	from	from	ADP
admet-2684	158	5	ro5	ro5	ADJ
admet-2684	158	6	and	and	CCONJ
admet-2684	158	7	the	the	DET
admet-2684	158	8	veber	veber	PROPN
admet-2684	158	9	rule	rule	NOUN
admet-2684	158	10	are	be	AUX
admet-2684	158	11	met	meet	VERB
admet-2684	158	12	by	by	ADP
admet-2684	158	13	the	the	DET
admet-2684	158	14	discussed	discuss	VERB
admet-2684	158	15	molecules	molecule	NOUN
admet-2684	158	16	.	.	PUNCT
admet-2684	159	1	therefore	therefore	ADV
admet-2684	159	2	,	,	PUNCT
admet-2684	159	3	it	it	PRON
admet-2684	159	4	is	be	AUX
admet-2684	159	5	possible	possible	ADJ
admet-2684	159	6	to	to	PART
admet-2684	159	7	assume	assume	VERB
admet-2684	159	8	that	that	SCONJ
admet-2684	159	9	the	the	DET
admet-2684	159	10	compounds	compound	NOUN
admet-2684	159	11	should	should	AUX
admet-2684	159	12	not	not	PART
admet-2684	159	13	have	have	VERB
admet-2684	159	14	serious	serious	ADJ
admet-2684	159	15	absorption	absorption	NOUN
admet-2684	159	16	problems	problem	NOUN
admet-2684	159	17	after	after	ADP
admet-2684	159	18	oral	oral	ADJ
admet-2684	159	19	administration	administration	NOUN
admet-2684	159	20	.	.	PUNCT
admet-2684	160	1	much	much	ADV
admet-2684	160	2	more	more	ADV
admet-2684	160	3	informative	informative	ADJ
admet-2684	160	4	results	result	NOUN
admet-2684	160	5	could	could	AUX
admet-2684	160	6	be	be	AUX
admet-2684	160	7	obtained	obtain	VERB
admet-2684	160	8	using	use	VERB
admet-2684	160	9	in	in	ADP
admet-2684	160	10	vitro	vitro	NOUN
admet-2684	160	11	or	or	CCONJ
admet-2684	160	12	in	in	ADP
admet-2684	160	13	vivo	vivo	ADJ
admet-2684	160	14	experiments	experiment	NOUN
admet-2684	160	15	,	,	PUNCT
admet-2684	160	16	which	which	PRON
admet-2684	160	17	are	be	AUX
admet-2684	160	18	more	more	ADJ
admet-2684	160	19	time	time	NOUN
admet-2684	160	20	-	-	PUNCT
admet-2684	160	21	consuming	consume	VERB
admet-2684	160	22	and	and	CCONJ
admet-2684	160	23	expensive	expensive	ADJ
admet-2684	160	24	[	[	X
admet-2684	160	25	70	70	NUM
admet-2684	160	26	]	]	PUNCT
admet-2684	160	27	.	.	PUNCT
admet-2684	161	1	in	in	ADP
admet-2684	161	2	vitro	vitro	X
admet-2684	161	3	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	161	4	activities	activity	NOUN
admet-2684	161	5	all	all	DET
admet-2684	161	6	the	the	DET
admet-2684	161	7	investigated	investigate	VERB
admet-2684	161	8	compounds	compound	NOUN
admet-2684	161	9	were	be	AUX
admet-2684	161	10	screened	screen	VERB
admet-2684	161	11	for	for	ADP
admet-2684	161	12	their	their	PRON
admet-2684	161	13	effect	effect	NOUN
admet-2684	161	14	against	against	ADP
admet-2684	161	15	s.	s.	PROPN
admet-2684	161	16	aureus	aureus	PROPN
admet-2684	161	17	,	,	PUNCT
admet-2684	161	18	as	as	ADP
admet-2684	161	19	an	an	DET
admet-2684	161	20	important	important	ADJ
admet-2684	161	21	cause	cause	NOUN
admet-2684	161	22	of	of	ADP
admet-2684	161	23	various	various	ADJ
admet-2684	161	24	bacterial	bacterial	ADJ
admet-2684	161	25	infections	infection	NOUN
admet-2684	161	26	[	[	X
admet-2684	161	27	51	51	NUM
admet-2684	161	28	]	]	PUNCT
admet-2684	161	29	.	.	PUNCT
admet-2684	162	1	s.	s.	PROPN
admet-2684	162	2	aureus	aureus	PROPN
admet-2684	162	3	atcc	atcc	PROPN
admet-2684	162	4	29213	29213	NUM
admet-2684	162	5	was	be	AUX
admet-2684	162	6	used	use	VERB
admet-2684	162	7	as	as	ADP
admet-2684	162	8	the	the	DET
admet-2684	162	9	reference	reference	NOUN
admet-2684	162	10	and	and	CCONJ
admet-2684	162	11	quality	quality	NOUN
admet-2684	162	12	control	control	NOUN
admet-2684	162	13	strain	strain	NOUN
admet-2684	162	14	,	,	PUNCT
admet-2684	162	15	and	and	CCONJ
admet-2684	162	16	in	in	ADP
admet-2684	162	17	addition	addition	NOUN
admet-2684	162	18	,	,	PUNCT
admet-2684	162	19	clinical	clinical	ADJ
admet-2684	162	20	isolates	isolate	NOUN
admet-2684	162	21	of	of	ADP
admet-2684	162	22	methicillin	methicillin	NOUN
admet-2684	162	23	-	-	PUNCT
admet-2684	162	24	resistant	resistant	ADJ
admet-2684	162	25	s.	s.	PROPN
admet-2684	162	26	aureus	aureus	PROPN
admet-2684	162	27	(	(	PUNCT
admet-2684	162	28	mrsa	mrsa	NOUN
admet-2684	162	29	)	)	PUNCT
admet-2684	162	30	63718	63718	NUM
admet-2684	162	31	,	,	PUNCT
admet-2684	162	32	sa	sa	NOUN
admet-2684	162	33	630	630	NUM
admet-2684	162	34	,	,	PUNCT
admet-2684	162	35	and	and	CCONJ
admet-2684	162	36	sa	sa	X
admet-2684	162	37	3202	3202	NUM
admet-2684	163	1	[	[	X
admet-2684	163	2	54	54	NUM
admet-2684	163	3	]	]	PUNCT
admet-2684	163	4	were	be	AUX
admet-2684	163	5	tested	test	VERB
admet-2684	163	6	.	.	PUNCT
admet-2684	164	1	these	these	DET
admet-2684	164	2	three	three	NUM
admet-2684	164	3	clinical	clinical	ADJ
admet-2684	164	4	mrsa	mrsa	NOUN
admet-2684	164	5	isolates	isolate	NOUN
admet-2684	164	6	of	of	ADP
admet-2684	164	7	human	human	ADJ
admet-2684	164	8	and	and	CCONJ
admet-2684	164	9	veterinary	veterinary	ADJ
admet-2684	164	10	origin	origin	NOUN
admet-2684	164	11	carry	carry	VERB
admet-2684	164	12	the	the	DET
admet-2684	164	13	meca	meca	NOUN
admet-2684	164	14	gene	gene	NOUN
admet-2684	164	15	,	,	PUNCT
admet-2684	164	16	which	which	PRON
admet-2684	164	17	causes	cause	VERB
admet-2684	164	18	their	their	PRON
admet-2684	164	19	resistance	resistance	NOUN
admet-2684	164	20	[	[	X
admet-2684	164	21	54	54	NUM
admet-2684	164	22	-	-	SYM
admet-2684	164	23	57	57	NUM
admet-2684	164	24	]	]	PUNCT
admet-2684	164	25	.	.	PUNCT
admet-2684	165	1	activities	activity	NOUN
admet-2684	165	2	are	be	AUX
admet-2684	165	3	expressed	express	VERB
admet-2684	165	4	as	as	ADP
admet-2684	165	5	the	the	DET
admet-2684	165	6	minimum	minimum	ADJ
admet-2684	165	7	inhibitory	inhibitory	ADJ
admet-2684	165	8	concentrations	concentration	NOUN
admet-2684	165	9	(	(	PUNCT
admet-2684	165	10	mics	mic	NOUN
admet-2684	165	11	)	)	PUNCT
admet-2684	165	12	,	,	PUNCT
admet-2684	165	13	see	see	VERB
admet-2684	165	14	table	table	NOUN
admet-2684	165	15	2	2	NUM
admet-2684	165	16	.	.	NOUN
admet-2684	165	17	0.2	0.2	NUM
admet-2684	165	18	0.4	0.4	NUM
admet-2684	165	19	0.6	0.6	NUM
admet-2684	165	20	0.8	0.8	NUM
admet-2684	165	21	1.0	1.0	NUM
admet-2684	165	22	1.2	1.2	NUM
admet-2684	165	23	1.4	1.4	NUM
admet-2684	165	24	0.2	0.2	NUM
admet-2684	165	25	0.4	0.4	NUM
admet-2684	165	26	0.6	0.6	NUM
admet-2684	165	27	0.8	0.8	NUM
admet-2684	165	28	1.0	1.0	NUM
admet-2684	165	29	1.2	1.2	NUM
admet-2684	165	30	lo	lo	NOUN
admet-2684	165	31	g	g	PROPN
admet-2684	165	32	k	k	PROPN
admet-2684	165	33	log	log	NOUN
admet-2684	166	1	d6.5	d6.5	X
admet-2684	166	2	r	r	NOUN
admet-2684	166	3	=	=	PUNCT
admet-2684	166	4	0.9462	0.9462	NUM
admet-2684	166	5	a	a	DET
admet-2684	166	6	0.2	0.2	NUM
admet-2684	166	7	0.4	0.4	NUM
admet-2684	166	8	0.6	0.6	NUM
admet-2684	166	9	0.8	0.8	NUM
admet-2684	166	10	1.0	1.0	NUM
admet-2684	166	11	1.2	1.2	NUM
admet-2684	166	12	1.4	1.4	NUM
admet-2684	166	13	0.2	0.2	NUM
admet-2684	166	14	0.4	0.4	NUM
admet-2684	166	15	0.6	0.6	NUM
admet-2684	166	16	0.8	0.8	NUM
admet-2684	166	17	1.0	1.0	NUM
admet-2684	166	18	1.2	1.2	NUM
admet-2684	166	19	lo	lo	NOUN
admet-2684	166	20	g	g	PROPN
admet-2684	166	21	k	k	PROPN
admet-2684	166	22	log	log	PROPN
admet-2684	167	1	d7.4	d7.4	NOUN
admet-2684	167	2	r	r	NOUN
admet-2684	167	3	=	=	SYM
admet-2684	167	4	0.9182	0.9182	NUM
admet-2684	167	5	b	b	NOUN
admet-2684	167	6	0.2	0.2	NUM
admet-2684	167	7	0.4	0.4	NUM
admet-2684	167	8	0.6	0.6	NUM
admet-2684	167	9	0.8	0.8	NUM
admet-2684	167	10	1.0	1.0	NUM
admet-2684	167	11	1.2	1.2	NUM
admet-2684	167	12	0.2	0.2	NUM
admet-2684	167	13	0.4	0.4	NUM
admet-2684	167	14	0.6	0.6	NUM
admet-2684	167	15	0.8	0.8	NUM
admet-2684	167	16	1.0	1.0	NUM
admet-2684	167	17	1.2	1.2	NUM
admet-2684	167	18	lo	lo	NOUN
admet-2684	167	19	g	g	PROPN
admet-2684	167	20	d	d	PROPN
admet-2684	167	21	6	6	NUM
admet-2684	167	22	.5	.5	NUM
admet-2684	167	23	log	log	NOUN
admet-2684	167	24	d7.4	d7.4	NOUN
admet-2684	167	25	r	r	NOUN
admet-2684	167	26	=	=	SYM
admet-2684	167	27	0.9982	0.9982	NUM
admet-2684	167	28	c	c	NOUN
admet-2684	167	29	0.0	0.0	NUM
admet-2684	167	30	0.2	0.2	NUM
admet-2684	167	31	0.4	0.4	NUM
admet-2684	167	32	0.6	0.6	NUM
admet-2684	167	33	0.8	0.8	NUM
admet-2684	167	34	1.0	1.0	NUM
admet-2684	167	35	1.2	1.2	NUM
admet-2684	167	36	1.4	1.4	NUM
admet-2684	167	37	2,6	2,6	NUM
admet-2684	167	38	-	-	NOUN
admet-2684	167	39	cl	cl	ADJ
admet-2684	167	40	h	h	NOUN
admet-2684	167	41	2,5	2,5	NUM
admet-2684	167	42	-	-	PUNCT
admet-2684	167	43	cl	cl	NOUN
admet-2684	167	44	2,3	2,3	NUM
admet-2684	167	45	-	-	NOUN
admet-2684	167	46	cl	cl	NOUN
admet-2684	167	47	2,4,5	2,4,5	NUM
admet-2684	167	48	-	-	PUNCT
admet-2684	167	49	cl	cl	NOUN
admet-2684	167	50	2	2	NUM
admet-2684	167	51	-	-	PUNCT
admet-2684	167	52	cl	cl	NOUN
admet-2684	167	53	2,4	2,4	NUM
admet-2684	167	54	-	-	PUNCT
admet-2684	167	55	cl	cl	NOUN
admet-2684	167	56	2,4,6	2,4,6	NUM
admet-2684	167	57	-	-	PUNCT
admet-2684	167	58	cl	cl	NOUN
admet-2684	167	59	3	3	NUM
admet-2684	167	60	-	-	PUNCT
admet-2684	167	61	cl	cl	NOUN
admet-2684	167	62	4	4	NUM
admet-2684	167	63	-	-	PUNCT
admet-2684	167	64	cl	cl	NOUN
admet-2684	167	65	3,4	3,4	NUM
admet-2684	167	66	-	-	PUNCT
admet-2684	167	67	cl	cl	NOUN
admet-2684	167	68	3,5	3,5	NUM
admet-2684	167	69	-	-	PUNCT
admet-2684	167	70	cl	cl	NOUN
admet-2684	167	71	3,4,5	3,4,5	NUM
admet-2684	167	72	-	-	PUNCT
admet-2684	167	73	cl	cl	NOUN
admet-2684	167	74	lo	lo	NOUN
admet-2684	167	75	g	g	PROPN
admet-2684	167	76	k	k	PROPN
admet-2684	167	77	compounds	compound	VERB
admet-2684	167	78	log	log	VERB
admet-2684	168	1	k	k	PROPN
admet-2684	168	2	log	log	PROPN
admet-2684	168	3	d6.5	d6.5	PROPN
admet-2684	168	4	log	log	NOUN
admet-2684	168	5	d7.4	d7.4	PROPN
admet-2684	168	6	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	168	7	l.	l.	PROPN
admet-2684	168	8	vrablova	vrablova	PROPN
admet-2684	168	9	et	et	PROPN
admet-2684	168	10	al	al	PROPN
admet-2684	168	11	.	.	PROPN
admet-2684	168	12	admet	admet	PROPN
admet-2684	168	13	&	&	CCONJ
admet-2684	168	14	dmpk	dmpk	PROPN
admet-2684	168	15	13(2	13(2	PROPN
admet-2684	168	16	)	)	PUNCT
admet-2684	168	17	(	(	PUNCT
admet-2684	168	18	2025	2025	NUM
admet-2684	168	19	)	)	PUNCT
admet-2684	168	20	2684	2684	NUM
admet-2684	168	21	8	8	NUM
admet-2684	168	22	table	table	NOUN
admet-2684	168	23	2	2	NUM
admet-2684	168	24	.	.	PUNCT
admet-2684	168	25	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	168	26	activity	activity	NOUN
admet-2684	168	27	(	(	PUNCT
admet-2684	168	28	mic	mic	NOUN
admet-2684	168	29	)	)	PUNCT
admet-2684	168	30	of	of	ADP
admet-2684	168	31	carboxanilides	carboxanilide	NOUN
admet-2684	168	32	1	1	NUM
admet-2684	168	33	-	-	SYM
admet-2684	168	34	13	13	NUM
admet-2684	168	35	compared	compare	VERB
admet-2684	168	36	to	to	ADP
admet-2684	168	37	ampicillin	ampicillin	PROPN
admet-2684	168	38	(	(	PUNCT
admet-2684	168	39	apc	apc	PROPN
admet-2684	168	40	)	)	PUNCT
admet-2684	168	41	and	and	CCONJ
admet-2684	168	42	ciprofloxacin	ciprofloxacin	PROPN
admet-2684	168	43	(	(	PUNCT
admet-2684	168	44	cpx	cpx	PROPN
admet-2684	168	45	)	)	PUNCT
admet-2684	168	46	,	,	PUNCT
admet-2684	168	47	and	and	CCONJ
admet-2684	168	48	cytotoxicity	cytotoxicity	NOUN
admet-2684	168	49	(	(	PUNCT
admet-2684	168	50	lc50	lc50	PROPN
admet-2684	168	51	)	)	PUNCT
admet-2684	168	52	in	in	ADP
admet-2684	168	53	the	the	DET
admet-2684	168	54	human	human	ADJ
admet-2684	168	55	monocytic	monocytic	ADJ
admet-2684	168	56	leukemia	leukemia	NOUN
admet-2684	168	57	cell	cell	NOUN
admet-2684	168	58	line	line	NOUN
admet-2684	168	59	(	(	PUNCT
admet-2684	168	60	thp-1	thp-1	ADP
admet-2684	168	61	)	)	PUNCT
admet-2684	168	62	compared	compare	VERB
admet-2684	168	63	to	to	ADP
admet-2684	168	64	oxaliplatin	oxaliplatin	PROPN
admet-2684	168	65	(	(	PUNCT
admet-2684	168	66	oxp	oxp	PROPN
admet-2684	168	67	)	)	PUNCT
admet-2684	168	68	and	and	CCONJ
admet-2684	168	69	camptothecin	camptothecin	PROPN
admet-2684	168	70	(	(	PUNCT
admet-2684	168	71	cmt	cmt	PROPN
admet-2684	168	72	)	)	PUNCT
admet-2684	168	73	comp	comp	NOUN
admet-2684	168	74	.	.	PUNCT
admet-2684	169	1	r	r	NOUN
admet-2684	169	2	mic	mic	NOUN
admet-2684	169	3	,	,	PUNCT
admet-2684	169	4	µm	µm	ADP
admet-2684	169	5	lc50	lc50	PROPN
admet-2684	169	6	,	,	PUNCT
admet-2684	169	7	µm	µm	ADP
admet-2684	169	8	thp-1	thp-1	ADP
admet-2684	169	9	s.	s.	PROPN
admet-2684	169	10	aureus	aureus	PROPN
admet-2684	169	11	mrsa	mrsa	NOUN
admet-2684	169	12	63718	63718	NUM
admet-2684	169	13	mrsa	mrsa	NOUN
admet-2684	169	14	sa	sa	NOUN
admet-2684	169	15	630	630	NUM
admet-2684	169	16	mrsa	mrsa	NOUN
admet-2684	169	17	sa	sa	NOUN
admet-2684	169	18	3202	3202	NUM
admet-2684	169	19	1	1	NUM
admet-2684	169	20	h	h	NOUN
admet-2684	169	21	>	>	X
admet-2684	169	22	972	972	NUM
admet-2684	169	23	>	>	SYM
admet-2684	169	24	972	972	NUM
admet-2684	170	1	243	243	NUM
admet-2684	170	2	121	121	NUM
admet-2684	170	3	>	>	SYM
admet-2684	170	4	20	20	NUM
admet-2684	171	1	[	[	SYM
admet-2684	171	2	29	29	NUM
admet-2684	171	3	]	]	SYM
admet-2684	171	4	2	2	NUM
admet-2684	171	5	2	2	NUM
admet-2684	171	6	-	-	PUNCT
admet-2684	171	7	cl	cl	NOUN
admet-2684	171	8	>	>	NOUN
admet-2684	171	9	859	859	NUM
admet-2684	171	10	>	>	SYM
admet-2684	171	11	859	859	NUM
admet-2684	171	12	>	>	SYM
admet-2684	171	13	859	859	NUM
admet-2684	171	14	>	>	SYM
admet-2684	171	15	859	859	NUM
admet-2684	171	16	3	3	NUM
admet-2684	171	17	3	3	NUM
admet-2684	171	18	-	-	PUNCT
admet-2684	171	19	cl	cl	NOUN
admet-2684	171	20	>	>	NOUN
admet-2684	171	21	859	859	NUM
admet-2684	171	22	>	>	SYM
admet-2684	171	23	859	859	NUM
admet-2684	171	24	429	429	NUM
admet-2684	171	25	107	107	NUM
admet-2684	171	26	>	>	SYM
admet-2684	171	27	20	20	NUM
admet-2684	172	1	[	[	SYM
admet-2684	172	2	29	29	NUM
admet-2684	172	3	]	]	SYM
admet-2684	172	4	4	4	NUM
admet-2684	172	5	4	4	NUM
admet-2684	172	6	-	-	PUNCT
admet-2684	172	7	cl	cl	NOUN
admet-2684	172	8	>	>	NOUN
admet-2684	172	9	859	859	NUM
admet-2684	172	10	>	>	SYM
admet-2684	172	11	859	859	NUM
admet-2684	172	12	429	429	NUM
admet-2684	172	13	107	107	NUM
admet-2684	172	14	>	>	SYM
admet-2684	172	15	20	20	NUM
admet-2684	172	16	[	[	SYM
admet-2684	172	17	29	29	NUM
admet-2684	172	18	]	]	SYM
admet-2684	172	19	5	5	NUM
admet-2684	172	20	2,3	2,3	NUM
admet-2684	172	21	-	-	NOUN
admet-2684	172	22	cl	cl	NOUN
admet-2684	172	23	770	770	NUM
admet-2684	172	24	770	770	NUM
admet-2684	172	25	770	770	NUM
admet-2684	172	26	770	770	NUM
admet-2684	172	27	6	6	NUM
admet-2684	172	28	2,4	2,4	NUM
admet-2684	172	29	-	-	PUNCT
admet-2684	172	30	cl	cl	NOUN
admet-2684	172	31	770	770	NUM
admet-2684	172	32	770	770	NUM
admet-2684	172	33	770	770	NUM
admet-2684	172	34	770	770	NUM
admet-2684	172	35	7	7	NUM
admet-2684	172	36	2,5	2,5	NUM
admet-2684	172	37	-	-	PUNCT
admet-2684	172	38	cl	cl	NOUN
admet-2684	172	39	770	770	NUM
admet-2684	172	40	770	770	NUM
admet-2684	172	41	770	770	NUM
admet-2684	172	42	770	770	NUM
admet-2684	172	43	8	8	NUM
admet-2684	172	44	2,6	2,6	NUM
admet-2684	172	45	-	-	NOUN
admet-2684	172	46	cl	cl	NOUN
admet-2684	172	47	48.2	48.2	NUM
admet-2684	172	48	48.2	48.2	NUM
admet-2684	172	49	48.2	48.2	NUM
admet-2684	172	50	48.2	48.2	NUM
admet-2684	172	51	>	>	SYM
admet-2684	172	52	30	30	NUM
admet-2684	172	53	9	9	NUM
admet-2684	172	54	3,4	3,4	NUM
admet-2684	172	55	-	-	PUNCT
admet-2684	172	56	cl	cl	NOUN
admet-2684	172	57	770	770	NUM
admet-2684	172	58	770	770	NUM
admet-2684	172	59	96.3	96.3	NUM
admet-2684	172	60	385	385	NUM
admet-2684	172	61	10	10	NUM
admet-2684	172	62	3,5	3,5	NUM
admet-2684	172	63	-	-	PUNCT
admet-2684	172	64	cl	cl	NOUN
admet-2684	172	65	0.37	0.37	NUM
admet-2684	172	66	0.37	0.37	NUM
admet-2684	172	67	0.37	0.37	NUM
admet-2684	172	68	0.37	0.37	NUM
admet-2684	172	69	>	>	PUNCT
admet-2684	172	70	30	30	NUM
admet-2684	172	71	11	11	NUM
admet-2684	172	72	2,4,5	2,4,5	NUM
admet-2684	172	73	-	-	PUNCT
admet-2684	172	74	cl	cl	NOUN
admet-2684	172	75	698	698	NUM
admet-2684	172	76	698	698	NUM
admet-2684	172	77	698	698	NUM
admet-2684	172	78	698	698	NUM
admet-2684	172	79	12	12	NUM
admet-2684	172	80	2,4,6	2,4,6	NUM
admet-2684	172	81	-	-	PUNCT
admet-2684	172	82	cl	cl	NOUN
admet-2684	172	83	698	698	NUM
admet-2684	172	84	698	698	NUM
admet-2684	172	85	698	698	NUM
admet-2684	172	86	698	698	NUM
admet-2684	172	87	13	13	NUM
admet-2684	172	88	3,4,5	3,4,5	NUM
admet-2684	172	89	-	-	PUNCT
admet-2684	172	90	cl	cl	NOUN
admet-2684	172	91	698	698	NUM
admet-2684	172	92	698	698	NUM
admet-2684	172	93	698	698	NUM
admet-2684	172	94	698	698	NUM
admet-2684	172	95	apc	apc	PROPN
admet-2684	172	96	5.72	5.72	NUM
admet-2684	172	97	45.8	45.8	NUM
admet-2684	172	98	45.8	45.8	NUM
admet-2684	172	99	45.8	45.8	NUM
admet-2684	172	100	0.8±0.1	0.8±0.1	NUM
admet-2684	173	1	cpx	cpx	NOUN
admet-2684	173	2	0.75	0.75	NUM
admet-2684	173	3	24.2	24.2	NUM
admet-2684	173	4	24.2	24.2	NUM
admet-2684	173	5	24.2	24.2	NUM
admet-2684	173	6	0.7±0.09	0.7±0.09	NUM
admet-2684	174	1	oxp	oxp	PRON
admet-2684	174	2	1.7±0.6	1.7±0.6	NUM
admet-2684	174	3	cmp	cmp	NOUN
admet-2684	174	4	0.16±0.07	0.16±0.07	NOUN
admet-2684	174	5	only	only	ADV
admet-2684	174	6	n-(3,5	n-(3,5	NOUN
admet-2684	174	7	-	-	PUNCT
admet-2684	174	8	dichlorophenyl)-1	dichlorophenyl)-1	NOUN
admet-2684	174	9	-	-	PUNCT
admet-2684	174	10	hydroxynaphthalene-2	hydroxynaphthalene-2	NOUN
admet-2684	174	11	-	-	PUNCT
admet-2684	174	12	carboxamide	carboxamide	NOUN
admet-2684	174	13	(	(	PUNCT
admet-2684	174	14	10	10	NUM
admet-2684	174	15	)	)	PUNCT
admet-2684	174	16	showed	show	VERB
admet-2684	174	17	significant	significant	ADJ
admet-2684	174	18	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	174	19	activity	activity	NOUN
admet-2684	174	20	against	against	ADP
admet-2684	174	21	the	the	DET
admet-2684	174	22	susceptible	susceptible	ADJ
admet-2684	174	23	strain	strain	NOUN
admet-2684	174	24	and	and	CCONJ
admet-2684	174	25	resistant	resistant	ADJ
admet-2684	174	26	isolates	isolate	NOUN
admet-2684	174	27	.	.	PUNCT
admet-2684	175	1	partial	partial	ADJ
admet-2684	175	2	activity	activity	NOUN
admet-2684	175	3	was	be	AUX
admet-2684	175	4	also	also	ADV
admet-2684	175	5	observed	observe	VERB
admet-2684	175	6	for	for	ADP
admet-2684	175	7	carboxamide	carboxamide	NOUN
admet-2684	175	8	8	8	NUM
admet-2684	175	9	.	.	PUNCT
admet-2684	176	1	the	the	DET
admet-2684	176	2	other	other	ADJ
admet-2684	176	3	tested	test	VERB
admet-2684	176	4	compounds	compound	NOUN
admet-2684	176	5	were	be	AUX
admet-2684	176	6	completely	completely	ADV
admet-2684	176	7	inactive	inactive	ADJ
admet-2684	176	8	.	.	PUNCT
admet-2684	177	1	therefore	therefore	ADV
admet-2684	177	2	,	,	PUNCT
admet-2684	177	3	no	no	DET
admet-2684	177	4	structure	structure	NOUN
admet-2684	177	5	-	-	PUNCT
admet-2684	177	6	activity	activity	NOUN
admet-2684	177	7	relationships	relationship	NOUN
admet-2684	177	8	can	can	AUX
admet-2684	177	9	be	be	AUX
admet-2684	177	10	discussed	discuss	VERB
admet-2684	177	11	from	from	ADP
admet-2684	177	12	this	this	DET
admet-2684	177	13	set	set	NOUN
admet-2684	177	14	;	;	PUNCT
admet-2684	177	15	it	it	PRON
admet-2684	177	16	can	can	AUX
admet-2684	177	17	only	only	ADV
admet-2684	177	18	be	be	AUX
admet-2684	177	19	stated	state	VERB
admet-2684	177	20	that	that	SCONJ
admet-2684	177	21	the	the	DET
admet-2684	177	22	introduction	introduction	NOUN
admet-2684	177	23	of	of	ADP
admet-2684	177	24	the	the	DET
admet-2684	177	25	second	second	ADJ
admet-2684	177	26	chlorine	chlorine	NOUN
admet-2684	177	27	substituent	substituent	NOUN
admet-2684	177	28	improves	improve	VERB
admet-2684	177	29	the	the	DET
admet-2684	177	30	biological	biological	ADJ
admet-2684	177	31	activity	activity	NOUN
admet-2684	177	32	compared	compare	VERB
admet-2684	177	33	to	to	ADP
admet-2684	177	34	the	the	DET
admet-2684	177	35	unsubstituted	unsubstituted	ADJ
admet-2684	177	36	derivative	derivative	ADJ
admet-2684	177	37	1	1	NUM
admet-2684	177	38	and	and	CCONJ
admet-2684	177	39	the	the	DET
admet-2684	177	40	monosubstituted	monosubstitute	VERB
admet-2684	177	41	compounds	compound	VERB
admet-2684	177	42	2	2	NUM
admet-2684	177	43	-	-	SYM
admet-2684	177	44	4	4	NUM
admet-2684	177	45	.	.	PUNCT
admet-2684	178	1	on	on	ADP
admet-2684	178	2	the	the	DET
admet-2684	178	3	contrary	contrary	NOUN
admet-2684	178	4	,	,	PUNCT
admet-2684	178	5	the	the	DET
admet-2684	178	6	third	third	ADJ
admet-2684	178	7	chlorine	chlorine	NOUN
admet-2684	178	8	atom	atom	NOUN
admet-2684	178	9	(	(	PUNCT
admet-2684	178	10	derivatives	derivative	NOUN
admet-2684	178	11	11	11	NUM
admet-2684	178	12	-	-	SYM
admet-2684	178	13	13	13	NUM
admet-2684	178	14	)	)	PUNCT
admet-2684	178	15	again	again	ADV
admet-2684	178	16	leads	lead	VERB
admet-2684	178	17	to	to	ADP
admet-2684	178	18	a	a	DET
admet-2684	178	19	loss	loss	NOUN
admet-2684	178	20	of	of	ADP
admet-2684	178	21	activity	activity	NOUN
admet-2684	178	22	.	.	PUNCT
admet-2684	179	1	given	give	VERB
admet-2684	179	2	that	that	SCONJ
admet-2684	179	3	both	both	CCONJ
admet-2684	179	4	active	active	ADJ
admet-2684	179	5	compounds	compound	NOUN
admet-2684	179	6	have	have	AUX
admet-2684	179	7	diametrically	diametrically	ADV
admet-2684	179	8	different	different	ADJ
admet-2684	179	9	lipophilicities	lipophilicitie	NOUN
admet-2684	179	10	(	(	PUNCT
admet-2684	179	11	log	log	NOUN
admet-2684	179	12	k	k	PROPN
admet-2684	179	13	0.9704	0.9704	NUM
admet-2684	179	14	vs.	vs.	ADP
admet-2684	179	15	0.5729	0.5729	NUM
admet-2684	179	16	)	)	PUNCT
admet-2684	179	17	and	and	CCONJ
admet-2684	179	18	also	also	ADV
admet-2684	179	19	distant	distant	ADJ
admet-2684	179	20	electron	electron	NOUN
admet-2684	179	21	-	-	PUNCT
admet-2684	179	22	withdrawing	withdraw	VERB
admet-2684	179	23	values	value	NOUN
admet-2684	179	24	(	(	PUNCT
admet-2684	179	25	σ(ar	σ(ar	NOUN
admet-2684	179	26	)	)	PUNCT
admet-2684	179	27	1.11	1.11	NUM
admet-2684	179	28	vs.	vs.	ADP
admet-2684	179	29	1.33	1.33	NUM
admet-2684	179	30	)	)	PUNCT
admet-2684	179	31	,	,	PUNCT
admet-2684	179	32	it	it	PRON
admet-2684	179	33	can	can	AUX
admet-2684	179	34	be	be	AUX
admet-2684	179	35	summarized	summarize	VERB
admet-2684	179	36	that	that	SCONJ
admet-2684	179	37	only	only	ADV
admet-2684	179	38	the	the	DET
admet-2684	179	39	position	position	NOUN
admet-2684	179	40	of	of	ADP
admet-2684	179	41	both	both	DET
admet-2684	179	42	chlorine	chlorine	NOUN
admet-2684	179	43	substituents	substituent	NOUN
admet-2684	179	44	significantly	significantly	ADV
admet-2684	179	45	affects	affect	VERB
admet-2684	179	46	biological	biological	ADJ
admet-2684	179	47	activity	activity	NOUN
admet-2684	179	48	,	,	PUNCT
admet-2684	179	49	as	as	SCONJ
admet-2684	179	50	discussed	discuss	VERB
admet-2684	179	51	,	,	PUNCT
admet-2684	179	52	e.g.	e.g.	ADV
admet-2684	179	53	in	in	ADP
admet-2684	179	54	[	[	PUNCT
admet-2684	179	55	45,47,71	45,47,71	NUM
admet-2684	179	56	-	-	SYM
admet-2684	179	57	73	73	NUM
admet-2684	179	58	]	]	PUNCT
admet-2684	179	59	.	.	PUNCT
admet-2684	180	1	however	however	ADV
admet-2684	180	2	,	,	PUNCT
admet-2684	180	3	it	it	PRON
admet-2684	180	4	should	should	AUX
admet-2684	180	5	be	be	AUX
admet-2684	180	6	noted	note	VERB
admet-2684	180	7	that	that	SCONJ
admet-2684	180	8	the	the	DET
admet-2684	180	9	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	180	10	activities	activity	NOUN
admet-2684	180	11	of	of	ADP
admet-2684	180	12	both	both	DET
admet-2684	180	13	compounds	compound	NOUN
admet-2684	180	14	against	against	ADP
admet-2684	180	15	all	all	DET
admet-2684	180	16	the	the	DET
admet-2684	180	17	tested	test	VERB
admet-2684	180	18	strains	strain	NOUN
admet-2684	180	19	are	be	AUX
admet-2684	180	20	similar	similar	ADJ
admet-2684	180	21	,	,	PUNCT
admet-2684	180	22	so	so	ADV
admet-2684	180	23	a	a	DET
admet-2684	180	24	specific	specific	ADJ
admet-2684	180	25	activity	activity	NOUN
admet-2684	180	26	against	against	ADP
admet-2684	180	27	staphylococcus	staphylococcus	NOUN
admet-2684	180	28	spp	spp	NOUN
admet-2684	180	29	.	.	PUNCT
admet-2684	181	1	can	can	AUX
admet-2684	181	2	be	be	AUX
admet-2684	181	3	speculated	speculate	VERB
admet-2684	181	4	.	.	PUNCT
admet-2684	182	1	a	a	DET
admet-2684	182	2	similar	similar	ADJ
admet-2684	182	3	type	type	NOUN
admet-2684	182	4	of	of	ADP
admet-2684	182	5	compounds	compound	NOUN
admet-2684	182	6	3	3	NUM
admet-2684	182	7	-	-	PUNCT
admet-2684	182	8	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	182	9	-	-	PUNCT
admet-2684	182	10	carboxanilides	carboxanilide	NOUN
admet-2684	182	11	was	be	AUX
admet-2684	182	12	evaluated	evaluate	VERB
admet-2684	182	13	for	for	ADP
admet-2684	182	14	their	their	PRON
admet-2684	182	15	combined	combine	VERB
admet-2684	182	16	effect	effect	NOUN
admet-2684	182	17	with	with	ADP
admet-2684	182	18	ciprofloxacin	ciprofloxacin	PROPN
admet-2684	182	19	and	and	CCONJ
admet-2684	182	20	oxacillin	oxacillin	NOUN
admet-2684	182	21	and	and	CCONJ
admet-2684	182	22	synergism	synergism	NOUN
admet-2684	182	23	was	be	AUX
admet-2684	182	24	found	find	VERB
admet-2684	182	25	in	in	ADP
admet-2684	182	26	combinations	combination	NOUN
admet-2684	182	27	with	with	ADP
admet-2684	182	28	ciprofloxacin	ciprofloxacin	NOUN
admet-2684	182	29	and	and	CCONJ
admet-2684	182	30	indifference	indifference	NOUN
admet-2684	182	31	in	in	ADP
admet-2684	182	32	combinations	combination	NOUN
admet-2684	182	33	with	with	ADP
admet-2684	182	34	oxacillin	oxacillin	PROPN
admet-2684	182	35	.	.	PUNCT
admet-2684	183	1	from	from	ADP
admet-2684	183	2	these	these	DET
admet-2684	183	3	facts	fact	NOUN
admet-2684	183	4	,	,	PUNCT
admet-2684	183	5	it	it	PRON
admet-2684	183	6	can	can	AUX
admet-2684	183	7	be	be	AUX
admet-2684	183	8	concluded	conclude	VERB
admet-2684	183	9	that	that	SCONJ
admet-2684	183	10	the	the	DET
admet-2684	183	11	compounds	compound	NOUN
admet-2684	183	12	have	have	VERB
admet-2684	183	13	their	their	PRON
admet-2684	183	14	specific	specific	ADJ
admet-2684	183	15	mechanism	mechanism	NOUN
admet-2684	183	16	of	of	ADP
admet-2684	183	17	action	action	NOUN
admet-2684	183	18	against	against	ADP
admet-2684	183	19	s.	s.	PROPN
admet-2684	183	20	aureus	aureus	PROPN
admet-2684	183	21	/	/	SYM
admet-2684	183	22	mrsa	mrsa	NOUN
admet-2684	183	23	without	without	ADP
admet-2684	183	24	any	any	DET
admet-2684	183	25	interference	interference	NOUN
admet-2684	183	26	with	with	ADP
admet-2684	183	27	the	the	DET
admet-2684	183	28	meca	meca	NOUN
admet-2684	183	29	gene	gene	NOUN
admet-2684	183	30	and	and	CCONJ
admet-2684	183	31	without	without	ADP
admet-2684	183	32	any	any	DET
admet-2684	183	33	interaction	interaction	NOUN
admet-2684	183	34	with	with	ADP
admet-2684	183	35	the	the	DET
admet-2684	183	36	cell	cell	NOUN
admet-2684	183	37	wall	wall	NOUN
admet-2684	183	38	.	.	PUNCT
admet-2684	184	1	on	on	ADP
admet-2684	184	2	the	the	DET
admet-2684	184	3	other	other	ADJ
admet-2684	184	4	hand	hand	NOUN
admet-2684	184	5	,	,	PUNCT
admet-2684	184	6	due	due	ADP
admet-2684	184	7	to	to	ADP
admet-2684	184	8	the	the	DET
admet-2684	184	9	synergism	synergism	NOUN
admet-2684	184	10	with	with	ADP
admet-2684	184	11	ciprofloxacin	ciprofloxacin	PROPN
admet-2684	184	12	,	,	PUNCT
admet-2684	184	13	a	a	DET
admet-2684	184	14	possible	possible	ADJ
admet-2684	184	15	inhibition	inhibition	NOUN
admet-2684	184	16	of	of	ADP
admet-2684	184	17	efflux	efflux	NOUN
admet-2684	184	18	pumps	pump	NOUN
admet-2684	184	19	could	could	AUX
admet-2684	184	20	be	be	AUX
admet-2684	184	21	hypothesized	hypothesize	VERB
admet-2684	184	22	[	[	PUNCT
admet-2684	184	23	74	74	NUM
admet-2684	184	24	]	]	PUNCT
admet-2684	184	25	.	.	PUNCT
admet-2684	185	1	mtt	mtt	PROPN
admet-2684	185	2	assay	assay	VERB
admet-2684	185	3	to	to	PART
admet-2684	185	4	contribute	contribute	VERB
admet-2684	185	5	to	to	ADP
admet-2684	185	6	the	the	DET
admet-2684	185	7	discovery	discovery	NOUN
admet-2684	185	8	of	of	ADP
admet-2684	185	9	one	one	NUM
admet-2684	185	10	of	of	ADP
admet-2684	185	11	the	the	DET
admet-2684	185	12	possible	possible	ADJ
admet-2684	185	13	mechanisms	mechanism	NOUN
admet-2684	185	14	of	of	ADP
admet-2684	185	15	action	action	NOUN
admet-2684	185	16	,	,	PUNCT
admet-2684	185	17	a	a	DET
admet-2684	185	18	standard	standard	ADJ
admet-2684	185	19	mtt	mtt	NOUN
admet-2684	185	20	assay	assay	NOUN
admet-2684	185	21	was	be	AUX
admet-2684	185	22	performed	perform	VERB
admet-2684	185	23	with	with	ADP
admet-2684	185	24	active	active	ADJ
admet-2684	185	25	compound	compound	NOUN
admet-2684	185	26	10	10	NUM
admet-2684	185	27	in	in	ADP
admet-2684	185	28	comparison	comparison	NOUN
admet-2684	185	29	with	with	ADP
admet-2684	185	30	the	the	DET
admet-2684	185	31	drugs	drug	NOUN
admet-2684	185	32	ampicillin	ampicillin	PROPN
admet-2684	185	33	and	and	CCONJ
admet-2684	185	34	ciprofloxacin	ciprofloxacin	NOUN
admet-2684	185	35	used	use	VERB
admet-2684	185	36	as	as	ADP
admet-2684	185	37	standards	standard	NOUN
admet-2684	185	38	.	.	PUNCT
admet-2684	186	1	the	the	DET
admet-2684	186	2	lowest	low	ADJ
admet-2684	186	3	multiples	multiple	NOUN
admet-2684	186	4	of	of	ADP
admet-2684	186	5	mic	mic	ADJ
admet-2684	186	6	values	value	NOUN
admet-2684	186	7	that	that	PRON
admet-2684	186	8	achieved	achieve	VERB
admet-2684	186	9	inhibition	inhibition	NOUN
admet-2684	186	10	of	of	ADP
admet-2684	186	11	s.	s.	PROPN
admet-2684	186	12	aureus	aureus	PROPN
admet-2684	186	13	atcc	atcc	PROPN
admet-2684	186	14	29213	29213	NUM
admet-2684	186	15	viability	viability	NOUN
admet-2684	186	16	greater	great	ADJ
admet-2684	186	17	than	than	ADP
admet-2684	186	18	70	70	NUM
admet-2684	186	19	%	%	NOUN
admet-2684	186	20	are	be	AUX
admet-2684	186	21	shown	show	VERB
admet-2684	186	22	in	in	ADP
admet-2684	186	23	table	table	NOUN
admet-2684	186	24	3	3	NUM
admet-2684	186	25	.	.	PUNCT
admet-2684	187	1	the	the	DET
admet-2684	187	2	mtt	mtt	NOUN
admet-2684	187	3	assay	assay	VERB
admet-2684	187	4	can	can	AUX
admet-2684	187	5	be	be	AUX
admet-2684	187	6	used	use	VERB
admet-2684	187	7	to	to	PART
admet-2684	187	8	assess	assess	VERB
admet-2684	187	9	cell	cell	NOUN
admet-2684	187	10	growth	growth	NOUN
admet-2684	187	11	by	by	ADP
admet-2684	187	12	measuring	measure	VERB
admet-2684	187	13	respiration	respiration	NOUN
admet-2684	187	14	.	.	PUNCT
admet-2684	188	1	the	the	DET
admet-2684	188	2	mtt	mtt	NOUN
admet-2684	188	3	-	-	PUNCT
admet-2684	188	4	measured	measure	VERB
admet-2684	188	5	viability	viability	NOUN
admet-2684	188	6	of	of	ADP
admet-2684	188	7	bacterial	bacterial	ADJ
admet-2684	188	8	cells	cell	NOUN
admet-2684	188	9	is	be	AUX
admet-2684	188	10	less	less	ADJ
admet-2684	188	11	than	than	ADP
admet-2684	188	12	70	70	NUM
admet-2684	188	13	%	%	NOUN
admet-2684	188	14	after	after	ADP
admet-2684	188	15	exposure	exposure	NOUN
admet-2684	188	16	to	to	ADP
admet-2684	188	17	the	the	DET
admet-2684	188	18	mic	mic	ADJ
admet-2684	188	19	values	value	NOUN
admet-2684	188	20	for	for	ADP
admet-2684	188	21	each	each	DET
admet-2684	188	22	tested	test	VERB
admet-2684	188	23	compound	compound	NOUN
admet-2684	188	24	,	,	PUNCT
admet-2684	188	25	which	which	PRON
admet-2684	188	26	is	be	AUX
admet-2684	188	27	considered	consider	VERB
admet-2684	188	28	a	a	DET
admet-2684	188	29	positive	positive	ADJ
admet-2684	188	30	result	result	NOUN
admet-2684	188	31	of	of	ADP
admet-2684	188	32	this	this	DET
admet-2684	188	33	assay	assay	NOUN
admet-2684	188	34	.	.	PUNCT
admet-2684	189	1	this	this	DET
admet-2684	189	2	low	low	ADJ
admet-2684	189	3	level	level	NOUN
admet-2684	189	4	of	of	ADP
admet-2684	189	5	cell	cell	NOUN
admet-2684	189	6	viability	viability	NOUN
admet-2684	189	7	indicates	indicate	VERB
admet-2684	189	8	inhibition	inhibition	NOUN
admet-2684	189	9	of	of	ADP
admet-2684	189	10	cell	cell	NOUN
admet-2684	189	11	growth	growth	NOUN
admet-2684	189	12	by	by	ADP
admet-2684	189	13	inhibition	inhibition	NOUN
admet-2684	189	14	of	of	ADP
admet-2684	189	15	respiration	respiration	NOUN
admet-2684	189	16	[	[	X
admet-2684	189	17	31,60,61	31,60,61	NUM
admet-2684	189	18	]	]	PUNCT
admet-2684	189	19	.	.	PUNCT
admet-2684	190	1	although	although	SCONJ
admet-2684	190	2	the	the	DET
admet-2684	190	3	tested	test	VERB
admet-2684	190	4	compound	compound	NOUN
admet-2684	190	5	showed	show	VERB
admet-2684	190	6	96	96	NUM
admet-2684	190	7	%	%	NOUN
admet-2684	190	8	inhibition	inhibition	NOUN
admet-2684	190	9	of	of	ADP
admet-2684	190	10	respiration	respiration	NOUN
admet-2684	190	11	,	,	PUNCT
admet-2684	190	12	this	this	DET
admet-2684	190	13	effect	effect	NOUN
admet-2684	190	14	occurred	occur	VERB
admet-2684	190	15	only	only	ADV
admet-2684	190	16	at	at	ADP
admet-2684	190	17	16×	16×	NUM
admet-2684	190	18	mic	mic	ADJ
admet-2684	190	19	,	,	PUNCT
admet-2684	190	20	i.e.	i.e.	X
admet-2684	190	21	at	at	ADP
admet-2684	190	22	a	a	DET
admet-2684	190	23	high	high	ADJ
admet-2684	190	24	concentration	concentration	NOUN
admet-2684	190	25	compared	compare	VERB
admet-2684	190	26	to	to	ADP
admet-2684	190	27	the	the	DET
admet-2684	190	28	inhibitory	inhibitory	ADJ
admet-2684	190	29	effect	effect	NOUN
admet-2684	190	30	on	on	ADP
admet-2684	190	31	growth	growth	NOUN
admet-2684	190	32	.	.	PUNCT
admet-2684	191	1	therefore	therefore	ADV
admet-2684	191	2	,	,	PUNCT
admet-2684	191	3	it	it	PRON
admet-2684	191	4	can	can	AUX
admet-2684	191	5	be	be	AUX
admet-2684	191	6	assumed	assume	VERB
admet-2684	191	7	that	that	SCONJ
admet-2684	191	8	the	the	DET
admet-2684	191	9	main	main	ADJ
admet-2684	191	10	mechanism	mechanism	NOUN
admet-2684	191	11	of	of	ADP
admet-2684	191	12	action	action	NOUN
admet-2684	191	13	is	be	AUX
admet-2684	191	14	not	not	PART
admet-2684	191	15	inhibition	inhibition	NOUN
admet-2684	191	16	of	of	ADP
admet-2684	191	17	the	the	DET
admet-2684	191	18	respiratory	respiratory	ADJ
admet-2684	191	19	chain	chain	NOUN
admet-2684	191	20	.	.	PUNCT
admet-2684	192	1	admet	admet	PROPN
admet-2684	192	2	&	&	CCONJ
admet-2684	192	3	dmpk	dmpk	PROPN
admet-2684	192	4	13(2	13(2	PROPN
admet-2684	192	5	)	)	PUNCT
admet-2684	192	6	(	(	PUNCT
admet-2684	192	7	2025	2025	NUM
admet-2684	192	8	)	)	PUNCT
admet-2684	192	9	2684	2684	NUM
admet-2684	192	10	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	192	11	effect	effect	NOUN
admet-2684	192	12	of	of	ADP
admet-2684	192	13	chlorinated	chlorinate	VERB
admet-2684	192	14	1	1	NUM
admet-2684	192	15	-	-	PUNCT
admet-2684	192	16	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	192	17	-	-	PUNCT
admet-2684	192	18	carboxanilides	carboxanilide	NOUN
admet-2684	192	19	doi	doi	NOUN
admet-2684	192	20	:	:	PUNCT
admet-2684	192	21	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	192	22	9	9	NUM
admet-2684	192	23	table	table	NOUN
admet-2684	192	24	3	3	NUM
admet-2684	192	25	.	.	PUNCT
admet-2684	192	26	lowest	low	ADJ
admet-2684	192	27	mic	mic	ADJ
admet-2684	192	28	values	value	NOUN
admet-2684	192	29	with	with	ADP
admet-2684	192	30	at	at	ADV
admet-2684	192	31	least	least	ADV
admet-2684	192	32	70	70	NUM
admet-2684	192	33	%	%	NOUN
admet-2684	192	34	inhibition	inhibition	NOUN
admet-2684	192	35	of	of	ADP
admet-2684	192	36	s.	s.	PROPN
admet-2684	192	37	aureus	aureus	PROPN
admet-2684	192	38	atcc	atcc	PROPN
admet-2684	192	39	29213	29213	NUM
admet-2684	192	40	viability	viability	NOUN
admet-2684	192	41	(	(	PUNCT
admet-2684	192	42	respiratory	respiratory	ADJ
admet-2684	192	43	activity	activity	NOUN
admet-2684	192	44	)	)	PUNCT
admet-2684	192	45	compounds	compound	VERB
admet-2684	192	46	concentration	concentration	NOUN
admet-2684	192	47	s.	s.	PROPN
admet-2684	192	48	aureus	aureus	PROPN
admet-2684	192	49	viability	viability	NOUN
admet-2684	192	50	inhibition	inhibition	NOUN
admet-2684	192	51	,	,	PUNCT
admet-2684	192	52	%	%	NOUN
admet-2684	193	1	10	10	NUM
admet-2684	193	2	16×	16×	NUM
admet-2684	193	3	mic	mic	ADJ
admet-2684	193	4	96.5	96.5	NUM
admet-2684	193	5	apc	apc	PROPN
admet-2684	193	6	8×	8×	NOUN
admet-2684	193	7	mic	mic	NOUN
admet-2684	193	8	90.0	90.0	NUM
admet-2684	193	9	cpx	cpx	NOUN
admet-2684	193	10	32×	32×	NUM
admet-2684	193	11	mic	mic	ADJ
admet-2684	193	12	92.8	92.8	NUM
admet-2684	193	13	cytotoxicity	cytotoxicity	NOUN
admet-2684	193	14	preliminary	preliminary	ADJ
admet-2684	193	15	in	in	ADP
admet-2684	193	16	vitro	vitro	X
admet-2684	193	17	cytotoxicity	cytotoxicity	NOUN
admet-2684	193	18	screening	screening	NOUN
admet-2684	193	19	of	of	ADP
admet-2684	193	20	selected	select	VERB
admet-2684	193	21	compounds	compound	NOUN
admet-2684	193	22	8	8	NUM
admet-2684	193	23	and	and	CCONJ
admet-2684	193	24	10	10	NUM
admet-2684	193	25	was	be	AUX
admet-2684	193	26	performed	perform	VERB
admet-2684	193	27	using	use	VERB
admet-2684	193	28	the	the	DET
admet-2684	193	29	human	human	ADJ
admet-2684	193	30	monocytic	monocytic	ADJ
admet-2684	193	31	leukemia	leukemia	NOUN
admet-2684	193	32	cell	cell	NOUN
admet-2684	193	33	line	line	NOUN
admet-2684	193	34	(	(	PUNCT
admet-2684	193	35	thp-1	thp-1	NOUN
admet-2684	193	36	)	)	PUNCT
admet-2684	193	37	.	.	PUNCT
admet-2684	194	1	cytotoxicity	cytotoxicity	NOUN
admet-2684	194	2	was	be	AUX
admet-2684	194	3	expressed	express	VERB
admet-2684	194	4	as	as	ADP
admet-2684	194	5	lc50	lc50	PROPN
admet-2684	194	6	value	value	NOUN
admet-2684	194	7	(	(	PUNCT
admet-2684	194	8	lethal	lethal	ADJ
admet-2684	194	9	concentration	concentration	NOUN
admet-2684	194	10	for	for	ADP
admet-2684	194	11	50	50	NUM
admet-2684	194	12	%	%	NOUN
admet-2684	194	13	of	of	ADP
admet-2684	194	14	the	the	DET
admet-2684	194	15	cell	cell	NOUN
admet-2684	194	16	population	population	NOUN
admet-2684	194	17	)	)	PUNCT
admet-2684	194	18	,	,	PUNCT
admet-2684	194	19	see	see	VERB
admet-2684	194	20	table	table	NOUN
admet-2684	194	21	2	2	NUM
admet-2684	194	22	.	.	PUNCT
admet-2684	194	23	treatment	treatment	NOUN
admet-2684	194	24	with	with	ADP
admet-2684	194	25	30	30	NUM
admet-2684	194	26	μm	μm	NOUN
admet-2684	194	27	did	do	AUX
admet-2684	194	28	not	not	PART
admet-2684	194	29	lead	lead	VERB
admet-2684	194	30	to	to	ADP
admet-2684	194	31	a	a	DET
admet-2684	194	32	significant	significant	ADJ
admet-2684	194	33	lethal	lethal	ADJ
admet-2684	194	34	effect	effect	NOUN
admet-2684	194	35	on	on	ADP
admet-2684	194	36	thp-1	thp-1	ADP
admet-2684	194	37	cells	cell	NOUN
admet-2684	194	38	(	(	PUNCT
admet-2684	194	39	e.g.	e.g.	ADV
admet-2684	194	40	the	the	DET
admet-2684	194	41	lc50	lc50	PROPN
admet-2684	194	42	values	value	NOUN
admet-2684	194	43	of	of	ADP
admet-2684	194	44	oxaliplatin	oxaliplatin	NOUN
admet-2684	194	45	and	and	CCONJ
admet-2684	194	46	camptothecin	camptothecin	NOUN
admet-2684	194	47	were	be	AUX
admet-2684	194	48	1.7±0.6	1.7±0.6	NUM
admet-2684	194	49	and	and	CCONJ
admet-2684	194	50	0.16±0.07	0.16±0.07	ADJ
admet-2684	194	51	μm	μm	NUM
admet-2684	194	52	,	,	PUNCT
admet-2684	194	53	respectively	respectively	ADV
admet-2684	194	54	)	)	PUNCT
admet-2684	194	55	.	.	PUNCT
admet-2684	195	1	for	for	ADP
admet-2684	195	2	comparison	comparison	NOUN
admet-2684	195	3	,	,	PUNCT
admet-2684	195	4	the	the	DET
admet-2684	195	5	lc50	lc50	PROPN
admet-2684	195	6	values	value	NOUN
admet-2684	195	7	of	of	ADP
admet-2684	195	8	ampicillin	ampicillin	NOUN
admet-2684	195	9	and	and	CCONJ
admet-2684	195	10	ciprofloxacin	ciprofloxacin	PROPN
admet-2684	195	11	were	be	AUX
admet-2684	195	12	0.8±0.1	0.8±0.1	NUM
admet-2684	195	13	and	and	CCONJ
admet-2684	195	14	0.7±0.1	0.7±0.1	NUM
admet-2684	195	15	μm	μm	NOUN
admet-2684	195	16	,	,	PUNCT
admet-2684	195	17	respectively	respectively	ADV
admet-2684	195	18	.	.	PUNCT
admet-2684	196	1	based	base	VERB
admet-2684	196	2	on	on	ADP
admet-2684	196	3	these	these	DET
admet-2684	196	4	observations	observation	NOUN
admet-2684	196	5	,	,	PUNCT
admet-2684	196	6	it	it	PRON
admet-2684	196	7	can	can	AUX
admet-2684	196	8	be	be	AUX
admet-2684	196	9	concluded	conclude	VERB
admet-2684	196	10	that	that	SCONJ
admet-2684	196	11	both	both	DET
admet-2684	196	12	tested	test	VERB
admet-2684	196	13	agents	agent	NOUN
admet-2684	196	14	can	can	AUX
admet-2684	196	15	be	be	AUX
admet-2684	196	16	considered	consider	VERB
admet-2684	196	17	non	non	ADJ
admet-2684	196	18	-	-	ADJ
admet-2684	196	19	toxic	toxic	ADJ
admet-2684	196	20	compounds	compound	NOUN
admet-2684	196	21	.	.	PUNCT
admet-2684	197	1	previously	previously	ADV
admet-2684	197	2	,	,	PUNCT
admet-2684	197	3	compounds	compound	VERB
admet-2684	197	4	1	1	NUM
admet-2684	197	5	,	,	PUNCT
admet-2684	197	6	3	3	NUM
admet-2684	197	7	and	and	CCONJ
admet-2684	197	8	4	4	NUM
admet-2684	197	9	were	be	AUX
admet-2684	197	10	also	also	ADV
admet-2684	197	11	tested	test	VERB
admet-2684	197	12	for	for	ADP
admet-2684	197	13	their	their	PRON
admet-2684	197	14	potential	potential	ADJ
admet-2684	197	15	cytotoxic	cytotoxic	ADJ
admet-2684	197	16	activity	activity	NOUN
admet-2684	197	17	in	in	ADP
admet-2684	197	18	thp-1	thp-1	ADP
admet-2684	197	19	cells	cell	NOUN
admet-2684	197	20	.	.	PUNCT
admet-2684	198	1	none	none	NOUN
admet-2684	198	2	of	of	ADP
admet-2684	198	3	them	they	PRON
admet-2684	198	4	induced	induce	VERB
admet-2684	198	5	significant	significant	ADJ
admet-2684	198	6	lethal	lethal	ADJ
admet-2684	198	7	effects	effect	NOUN
admet-2684	198	8	by	by	ADP
admet-2684	198	9	any	any	DET
admet-2684	198	10	tested	test	VERB
admet-2684	198	11	concentrations	concentration	NOUN
admet-2684	198	12	up	up	ADP
admet-2684	198	13	to	to	PART
admet-2684	198	14	20	20	NUM
admet-2684	198	15	μm	μm	NOUN
admet-2684	199	1	[	[	X
admet-2684	199	2	29	29	NUM
admet-2684	199	3	]	]	PUNCT
admet-2684	199	4	.	.	PUNCT
admet-2684	200	1	thus	thus	ADV
admet-2684	200	2	,	,	PUNCT
admet-2684	200	3	compounds	compound	VERB
admet-2684	200	4	1	1	NUM
admet-2684	200	5	,	,	PUNCT
admet-2684	200	6	3	3	NUM
admet-2684	200	7	and	and	CCONJ
admet-2684	200	8	4	4	NUM
admet-2684	200	9	could	could	AUX
admet-2684	200	10	also	also	ADV
admet-2684	200	11	be	be	AUX
admet-2684	200	12	considered	consider	VERB
admet-2684	200	13	non	non	ADJ
admet-2684	200	14	-	-	ADJ
admet-2684	200	15	toxic	toxic	ADJ
admet-2684	200	16	substances	substance	NOUN
admet-2684	200	17	.	.	PUNCT
admet-2684	201	1	chemoproteomic	chemoproteomic	ADJ
admet-2684	201	2	analysis	analysis	NOUN
admet-2684	201	3	in	in	ADP
admet-2684	201	4	order	order	NOUN
admet-2684	201	5	to	to	PART
admet-2684	201	6	gain	gain	VERB
admet-2684	201	7	a	a	DET
admet-2684	201	8	deeper	deep	ADJ
admet-2684	201	9	understanding	understanding	NOUN
admet-2684	201	10	of	of	ADP
admet-2684	201	11	what	what	PRON
admet-2684	201	12	happens	happen	VERB
admet-2684	201	13	in	in	ADP
admet-2684	201	14	the	the	DET
admet-2684	201	15	staphylococcal	staphylococcal	ADJ
admet-2684	201	16	cell	cell	NOUN
admet-2684	201	17	after	after	ADP
admet-2684	201	18	exposure	exposure	NOUN
admet-2684	201	19	to	to	ADP
admet-2684	201	20	these	these	DET
admet-2684	201	21	chlorinated	chlorinate	VERB
admet-2684	201	22	derivatives	derivative	NOUN
admet-2684	201	23	,	,	PUNCT
admet-2684	201	24	a	a	DET
admet-2684	201	25	primary	primary	ADJ
admet-2684	201	26	chemoproteomic	chemoproteomic	ADJ
admet-2684	201	27	study	study	NOUN
admet-2684	201	28	was	be	AUX
admet-2684	201	29	performed	perform	VERB
admet-2684	201	30	using	use	VERB
admet-2684	201	31	the	the	DET
admet-2684	201	32	abpp	abpp	NOUN
admet-2684	201	33	approach	approach	NOUN
admet-2684	201	34	with	with	ADP
admet-2684	201	35	lcms	lcms	PROPN
admet-2684	201	36	/	/	SYM
admet-2684	201	37	ms	ms	PROPN
admet-2684	201	38	detection	detection	NOUN
admet-2684	201	39	.	.	PUNCT
admet-2684	202	1	the	the	DET
admet-2684	202	2	discussed	discuss	VERB
admet-2684	202	3	dichlorinated	dichlorinated	ADJ
admet-2684	202	4	derivatives	derivative	NOUN
admet-2684	202	5	were	be	AUX
admet-2684	202	6	tested	test	VERB
admet-2684	202	7	against	against	ADP
admet-2684	202	8	s.	s.	PROPN
admet-2684	202	9	aureus	aureus	PROPN
admet-2684	202	10	atcc	atcc	PROPN
admet-2684	202	11	29213	29213	NUM
admet-2684	202	12	strain	strain	NOUN
admet-2684	202	13	and	and	CCONJ
admet-2684	202	14	mrsa	mrsa	NOUN
admet-2684	202	15	sa	sa	NOUN
admet-2684	202	16	630	630	NUM
admet-2684	202	17	isolate	isolate	NOUN
admet-2684	202	18	:	:	PUNCT
admet-2684	202	19	compound	compound	NOUN
admet-2684	202	20	10	10	NUM
admet-2684	202	21	with	with	ADP
admet-2684	202	22	high	high	ADJ
admet-2684	202	23	antibacterial	antibacterial	ADJ
admet-2684	202	24	activity	activity	NOUN
admet-2684	202	25	and	and	CCONJ
admet-2684	202	26	compound	compound	NOUN
admet-2684	202	27	9	9	NUM
admet-2684	202	28	,	,	PUNCT
admet-2684	202	29	a	a	DET
admet-2684	202	30	molecule	molecule	NOUN
admet-2684	202	31	with	with	ADP
admet-2684	202	32	no	no	DET
admet-2684	202	33	antibacterial	antibacterial	ADJ
admet-2684	202	34	effect	effect	NOUN
admet-2684	202	35	for	for	ADP
admet-2684	202	36	comparison	comparison	NOUN
admet-2684	202	37	,	,	PUNCT
admet-2684	202	38	as	as	SCONJ
admet-2684	202	39	these	these	DET
admet-2684	202	40	xenobiotics	xenobiotic	NOUN
admet-2684	202	41	cause	cause	VERB
admet-2684	202	42	cell	cell	NOUN
admet-2684	202	43	stress	stress	NOUN
admet-2684	202	44	but	but	CCONJ
admet-2684	202	45	do	do	AUX
admet-2684	202	46	not	not	PART
admet-2684	202	47	lead	lead	VERB
admet-2684	202	48	to	to	ADP
admet-2684	202	49	bacterial	bacterial	ADJ
admet-2684	202	50	cell	cell	NOUN
admet-2684	202	51	death	death	NOUN
admet-2684	202	52	.	.	PUNCT
admet-2684	203	1	in	in	ADP
admet-2684	203	2	addition	addition	NOUN
admet-2684	203	3	,	,	PUNCT
admet-2684	203	4	the	the	DET
admet-2684	203	5	experiment	experiment	NOUN
admet-2684	203	6	was	be	AUX
admet-2684	203	7	performed	perform	VERB
admet-2684	203	8	by	by	ADP
admet-2684	203	9	culturing	culture	VERB
admet-2684	203	10	s.	s.	PROPN
admet-2684	203	11	aureus	aureus	PROPN
admet-2684	203	12	/	/	SYM
admet-2684	203	13	mrsa	mrsa	NOUN
admet-2684	203	14	without	without	ADP
admet-2684	203	15	the	the	DET
admet-2684	203	16	addition	addition	NOUN
admet-2684	203	17	of	of	ADP
admet-2684	203	18	the	the	DET
admet-2684	203	19	tested	test	VERB
admet-2684	203	20	molecules	molecule	NOUN
admet-2684	203	21	(	(	PUNCT
admet-2684	203	22	control	control	NOUN
admet-2684	203	23	sample	sample	NOUN
admet-2684	203	24	,	,	PUNCT
admet-2684	203	25	cn	cn	PROPN
admet-2684	203	26	)	)	PUNCT
admet-2684	203	27	.	.	PUNCT
admet-2684	204	1	in	in	ADP
admet-2684	204	2	this	this	DET
admet-2684	204	3	way	way	NOUN
admet-2684	204	4	,	,	PUNCT
admet-2684	204	5	the	the	DET
admet-2684	204	6	following	follow	VERB
admet-2684	204	7	information	information	NOUN
admet-2684	204	8	was	be	AUX
admet-2684	204	9	obtained	obtain	VERB
admet-2684	204	10	:	:	PUNCT
admet-2684	204	11	(	(	PUNCT
admet-2684	204	12	i	i	NOUN
admet-2684	204	13	)	)	PUNCT
admet-2684	204	14	about	about	ADP
admet-2684	204	15	the	the	DET
admet-2684	204	16	representation	representation	NOUN
admet-2684	204	17	of	of	ADP
admet-2684	204	18	proteins	protein	NOUN
admet-2684	204	19	in	in	ADP
admet-2684	204	20	native	native	ADJ
admet-2684	204	21	bacteria	bacteria	NOUN
admet-2684	204	22	(	(	PUNCT
admet-2684	204	23	cn	cn	PROPN
admet-2684	204	24	)	)	PUNCT
admet-2684	204	25	;	;	PUNCT
admet-2684	204	26	(	(	PUNCT
admet-2684	204	27	ii	ii	X
admet-2684	204	28	)	)	PUNCT
admet-2684	204	29	the	the	DET
admet-2684	204	30	change	change	NOUN
admet-2684	204	31	in	in	ADP
admet-2684	204	32	the	the	DET
admet-2684	204	33	protein	protein	NOUN
admet-2684	204	34	profile	profile	NOUN
admet-2684	204	35	after	after	ADP
admet-2684	204	36	exposure	exposure	NOUN
admet-2684	204	37	to	to	ADP
admet-2684	204	38	an	an	DET
admet-2684	204	39	inactive	inactive	ADJ
admet-2684	204	40	substance	substance	NOUN
admet-2684	204	41	(	(	PUNCT
admet-2684	204	42	cn	cn	X
admet-2684	204	43	vs.	vs.	ADP
admet-2684	204	44	9	9	NUM
admet-2684	204	45	)	)	PUNCT
admet-2684	204	46	;	;	PUNCT
admet-2684	204	47	and	and	CCONJ
admet-2684	204	48	(	(	PUNCT
admet-2684	204	49	iii	iii	X
admet-2684	204	50	)	)	PUNCT
admet-2684	204	51	changes	change	NOUN
admet-2684	204	52	in	in	ADP
admet-2684	204	53	the	the	DET
admet-2684	204	54	protein	protein	NOUN
admet-2684	204	55	profile	profile	NOUN
admet-2684	204	56	induced	induce	VERB
admet-2684	204	57	by	by	ADP
admet-2684	204	58	the	the	DET
admet-2684	204	59	active	active	ADJ
admet-2684	204	60	agent	agent	NOUN
admet-2684	204	61	(	(	PUNCT
admet-2684	204	62	cn	cn	PROPN
admet-2684	204	63	vs.	vs.	ADP
admet-2684	204	64	9	9	NUM
admet-2684	204	65	vs.	vs.	ADP
admet-2684	204	66	10	10	NUM
admet-2684	204	67	)	)	PUNCT
admet-2684	204	68	.	.	PUNCT
admet-2684	205	1	this	this	PRON
admet-2684	205	2	allows	allow	VERB
admet-2684	205	3	us	we	PRON
admet-2684	205	4	to	to	PART
admet-2684	205	5	filter	filter	VERB
admet-2684	205	6	out	out	ADP
admet-2684	205	7	misleading	mislead	VERB
admet-2684	205	8	information	information	NOUN
admet-2684	205	9	that	that	PRON
admet-2684	205	10	does	do	AUX
admet-2684	205	11	not	not	PART
admet-2684	205	12	lead	lead	VERB
admet-2684	205	13	to	to	ADP
admet-2684	205	14	a	a	DET
admet-2684	205	15	substantial	substantial	ADJ
admet-2684	205	16	effect	effect	NOUN
admet-2684	205	17	on	on	ADP
admet-2684	205	18	the	the	DET
admet-2684	205	19	viability	viability	NOUN
admet-2684	205	20	of	of	ADP
admet-2684	205	21	the	the	DET
admet-2684	205	22	studied	studied	ADJ
admet-2684	205	23	staphylococci	staphylococci	PROPN
admet-2684	205	24	.	.	PUNCT
admet-2684	206	1	the	the	DET
admet-2684	206	2	results	result	NOUN
admet-2684	206	3	of	of	ADP
admet-2684	206	4	the	the	DET
admet-2684	206	5	proteomic	proteomic	ADJ
admet-2684	206	6	analysis	analysis	NOUN
admet-2684	206	7	are	be	AUX
admet-2684	206	8	interpreted	interpret	VERB
admet-2684	206	9	graphically	graphically	ADV
admet-2684	206	10	as	as	ADP
admet-2684	206	11	heatmaps	heatmap	NOUN
admet-2684	206	12	and	and	CCONJ
admet-2684	206	13	volcano	volcano	NOUN
admet-2684	206	14	plots	plot	NOUN
admet-2684	206	15	,	,	PUNCT
admet-2684	206	16	where	where	SCONJ
admet-2684	206	17	differences	difference	NOUN
admet-2684	206	18	in	in	ADP
admet-2684	206	19	protein	protein	NOUN
admet-2684	206	20	levels	level	NOUN
admet-2684	206	21	between	between	ADP
admet-2684	206	22	samples	sample	NOUN
admet-2684	206	23	are	be	AUX
admet-2684	206	24	clearly	clearly	ADV
admet-2684	206	25	visible	visible	ADJ
admet-2684	206	26	.	.	PUNCT
admet-2684	207	1	both	both	DET
admet-2684	207	2	types	type	NOUN
admet-2684	207	3	of	of	ADP
admet-2684	207	4	plots	plot	NOUN
admet-2684	207	5	are	be	AUX
admet-2684	207	6	created	create	VERB
admet-2684	207	7	using	use	VERB
admet-2684	207	8	the	the	DET
admet-2684	207	9	web	web	NOUN
admet-2684	207	10	platform	platform	NOUN
admet-2684	207	11	metaboanalyst	metaboanalyst	NOUN
admet-2684	207	12	6.0	6.0	NUM
admet-2684	208	1	[	[	X
admet-2684	208	2	75	75	NUM
admet-2684	208	3	]	]	PUNCT
admet-2684	208	4	,	,	PUNCT
admet-2684	208	5	and	and	CCONJ
admet-2684	208	6	brief	brief	ADJ
admet-2684	208	7	information	information	NOUN
admet-2684	208	8	about	about	ADP
admet-2684	208	9	the	the	DET
admet-2684	208	10	function	function	NOUN
admet-2684	208	11	of	of	ADP
admet-2684	208	12	proteins	protein	NOUN
admet-2684	208	13	and	and	CCONJ
admet-2684	208	14	their	their	PRON
admet-2684	208	15	assignment	assignment	NOUN
admet-2684	208	16	to	to	ADP
admet-2684	208	17	specific	specific	ADJ
admet-2684	208	18	biochemical	biochemical	ADJ
admet-2684	208	19	pathways	pathway	NOUN
admet-2684	208	20	was	be	AUX
admet-2684	208	21	obtained	obtain	VERB
admet-2684	208	22	from	from	ADP
admet-2684	208	23	the	the	DET
admet-2684	208	24	freely	freely	ADV
admet-2684	208	25	available	available	ADJ
admet-2684	208	26	uniprot	uniprot	ADJ
admet-2684	208	27	database	database	NOUN
admet-2684	209	1	[	[	X
admet-2684	209	2	64	64	NUM
admet-2684	209	3	]	]	PUNCT
admet-2684	209	4	.	.	PUNCT
admet-2684	210	1	from	from	ADP
admet-2684	210	2	each	each	DET
admet-2684	210	3	protein	protein	NOUN
admet-2684	210	4	set	set	VERB
admet-2684	210	5	of	of	ADP
admet-2684	210	6	approximately	approximately	ADV
admet-2684	210	7	100	100	NUM
admet-2684	210	8	proteins	protein	NOUN
admet-2684	210	9	,	,	PUNCT
admet-2684	210	10	the	the	DET
admet-2684	210	11	50	50	NUM
admet-2684	210	12	proteins	protein	NOUN
admet-2684	210	13	exhibiting	exhibit	VERB
admet-2684	210	14	the	the	DET
admet-2684	210	15	most	most	ADV
admet-2684	210	16	significant	significant	ADJ
admet-2684	210	17	changes	change	NOUN
admet-2684	210	18	were	be	AUX
admet-2684	210	19	selected	select	VERB
admet-2684	210	20	for	for	ADP
admet-2684	210	21	the	the	DET
admet-2684	210	22	heatmaps	heatmap	NOUN
admet-2684	210	23	.	.	PUNCT
admet-2684	211	1	each	each	DET
admet-2684	211	2	colored	colored	ADJ
admet-2684	211	3	cell	cell	NOUN
admet-2684	211	4	on	on	ADP
admet-2684	211	5	the	the	DET
admet-2684	211	6	map	map	NOUN
admet-2684	211	7	corresponds	correspond	VERB
admet-2684	211	8	to	to	ADP
admet-2684	211	9	the	the	DET
admet-2684	211	10	value	value	NOUN
admet-2684	211	11	of	of	ADP
admet-2684	211	12	the	the	DET
admet-2684	211	13	protein	protein	NOUN
admet-2684	211	14	peak	peak	NOUN
admet-2684	211	15	area	area	NOUN
admet-2684	211	16	in	in	ADP
admet-2684	211	17	the	the	DET
admet-2684	211	18	data	datum	NOUN
admet-2684	211	19	table	table	NOUN
admet-2684	211	20	,	,	PUNCT
admet-2684	211	21	with	with	ADP
admet-2684	211	22	samples	sample	NOUN
admet-2684	211	23	in	in	ADP
admet-2684	211	24	rows	row	NOUN
admet-2684	211	25	and	and	CCONJ
admet-2684	211	26	proteins	protein	NOUN
admet-2684	211	27	in	in	ADP
admet-2684	211	28	columns	column	NOUN
admet-2684	211	29	.	.	PUNCT
admet-2684	212	1	the	the	DET
admet-2684	212	2	heatmap	heatmap	NOUN
admet-2684	212	3	in	in	ADP
admet-2684	212	4	figure	figure	NOUN
admet-2684	212	5	4a	4a	NOUN
admet-2684	212	6	shows	show	VERB
admet-2684	212	7	the	the	DET
admet-2684	212	8	differences	difference	NOUN
admet-2684	212	9	in	in	ADP
admet-2684	212	10	protein	protein	NOUN
admet-2684	212	11	expression	expression	NOUN
admet-2684	212	12	between	between	ADP
admet-2684	212	13	the	the	DET
admet-2684	212	14	control	control	NOUN
admet-2684	212	15	s.	s.	PROPN
admet-2684	212	16	aureus	aureus	PROPN
admet-2684	212	17	sample	sample	NOUN
admet-2684	212	18	(	(	PUNCT
admet-2684	212	19	i.e.	i.e.	X
admet-2684	212	20	without	without	ADP
admet-2684	212	21	treatment	treatment	NOUN
admet-2684	212	22	with	with	ADP
admet-2684	212	23	any	any	DET
admet-2684	212	24	compound	compound	NOUN
admet-2684	212	25	,	,	PUNCT
admet-2684	212	26	cn	cn	PROPN
admet-2684	212	27	)	)	PUNCT
admet-2684	212	28	and	and	CCONJ
admet-2684	212	29	s.	s.	PROPN
admet-2684	212	30	aureus	aureus	PROPN
admet-2684	212	31	treated	treat	VERB
admet-2684	212	32	with	with	ADP
admet-2684	212	33	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	212	34	inactive	inactive	ADJ
admet-2684	212	35	compound	compound	NOUN
admet-2684	212	36	9	9	NUM
admet-2684	212	37	and	and	CCONJ
admet-2684	212	38	active	active	ADJ
admet-2684	212	39	agent	agent	NOUN
admet-2684	212	40	10	10	NUM
admet-2684	212	41	.	.	PUNCT
admet-2684	213	1	it	it	PRON
admet-2684	213	2	is	be	AUX
admet-2684	213	3	clear	clear	ADJ
admet-2684	213	4	from	from	ADP
admet-2684	213	5	the	the	DET
admet-2684	213	6	heatmap	heatmap	NOUN
admet-2684	213	7	(	(	PUNCT
admet-2684	213	8	figure	figure	NOUN
admet-2684	213	9	4a	4a	NUM
admet-2684	213	10	)	)	PUNCT
admet-2684	213	11	that	that	PRON
admet-2684	213	12	inactive	inactive	ADJ
admet-2684	213	13	9	9	NUM
admet-2684	213	14	caused	cause	VERB
admet-2684	213	15	changes	change	NOUN
admet-2684	213	16	in	in	ADP
admet-2684	213	17	the	the	DET
admet-2684	213	18	proteome	proteome	NOUN
admet-2684	213	19	more	more	ADV
admet-2684	213	20	significantly	significantly	ADV
admet-2684	213	21	compared	compare	VERB
admet-2684	213	22	to	to	ADP
admet-2684	213	23	active	active	ADJ
admet-2684	213	24	10	10	NUM
admet-2684	213	25	.	.	PUNCT
admet-2684	214	1	the	the	DET
admet-2684	214	2	active	active	ADJ
admet-2684	214	3	agent	agent	NOUN
admet-2684	214	4	specifically	specifically	ADV
admet-2684	214	5	caused	cause	VERB
admet-2684	214	6	downregulation	downregulation	NOUN
admet-2684	214	7	of	of	ADP
admet-2684	214	8	the	the	DET
admet-2684	214	9	following	follow	VERB
admet-2684	214	10	proteins	protein	NOUN
admet-2684	214	11	(	(	PUNCT
admet-2684	214	12	their	their	PRON
admet-2684	214	13	function	function	NOUN
admet-2684	214	14	is	be	AUX
admet-2684	214	15	listed	list	VERB
admet-2684	214	16	in	in	ADP
admet-2684	214	17	table	table	NOUN
admet-2684	214	18	4	4	NUM
admet-2684	214	19	):	):	PUNCT
admet-2684	214	20	probable	probable	ADJ
admet-2684	214	21	tautomerase	tautomerase	NOUN
admet-2684	214	22	sav1363	sav1363	NOUN
admet-2684	214	23	(	(	PUNCT
admet-2684	214	24	p67526	p67526	NOUN
admet-2684	214	25	)	)	PUNCT
admet-2684	214	26	,	,	PUNCT
admet-2684	214	27	ribonuclease	ribonuclease	NOUN
admet-2684	214	28	j2	j2	NOUN
admet-2684	214	29	(	(	PUNCT
admet-2684	214	30	q5hpr6	q5hpr6	NOUN
admet-2684	214	31	)	)	PUNCT
admet-2684	214	32	,	,	PUNCT
admet-2684	214	33	atp	atp	NOUN
admet-2684	214	34	-	-	PUNCT
admet-2684	214	35	dependent	dependent	ADJ
admet-2684	214	36	protease	protease	NOUN
admet-2684	214	37	atpase	atpase	NOUN
admet-2684	214	38	subunit	subunit	NOUN
admet-2684	214	39	hslu	hslu	NOUN
admet-2684	214	40	(	(	PUNCT
admet-2684	214	41	q5hpt8	q5hpt8	X
admet-2684	214	42	)	)	PUNCT
admet-2684	214	43	,	,	PUNCT
admet-2684	214	44	adenylosuccinate	adenylosuccinate	ADJ
admet-2684	214	45	synthetase	synthetase	NOUN
admet-2684	214	46	(	(	PUNCT
admet-2684	214	47	p65884	p65884	PROPN
admet-2684	214	48	)	)	PUNCT
admet-2684	214	49	.	.	PUNCT
admet-2684	215	1	arsenate	arsenate	ADJ
admet-2684	215	2	reductase	reductase	NOUN
admet-2684	215	3	(	(	PUNCT
admet-2684	215	4	p0a005	p0a005	PROPN
admet-2684	215	5	)	)	PUNCT
admet-2684	215	6	was	be	AUX
admet-2684	215	7	reduced	reduce	VERB
admet-2684	215	8	by	by	ADP
admet-2684	215	9	both	both	DET
admet-2684	215	10	derivatives	derivative	NOUN
admet-2684	215	11	to	to	ADP
admet-2684	215	12	a	a	DET
admet-2684	215	13	similar	similar	ADJ
admet-2684	215	14	level	level	NOUN
admet-2684	215	15	.	.	PUNCT
admet-2684	216	1	the	the	DET
admet-2684	216	2	heatmap	heatmap	NOUN
admet-2684	216	3	in	in	ADP
admet-2684	216	4	figure	figure	NOUN
admet-2684	216	5	4b	4b	PROPN
admet-2684	216	6	comparing	compare	VERB
admet-2684	216	7	the	the	DET
admet-2684	216	8	mrsa	mrsa	NOUN
admet-2684	216	9	control	control	NOUN
admet-2684	216	10	sample	sample	NOUN
admet-2684	216	11	with	with	ADP
admet-2684	216	12	samples	sample	NOUN
admet-2684	216	13	9	9	NUM
admet-2684	216	14	and	and	CCONJ
admet-2684	216	15	10	10	NUM
admet-2684	216	16	shows	show	VERB
admet-2684	216	17	smaller	small	ADJ
admet-2684	216	18	protein	protein	NOUN
admet-2684	216	19	sets	set	NOUN
admet-2684	216	20	compared	compare	VERB
admet-2684	216	21	to	to	PART
admet-2684	216	22	figure	figure	VERB
admet-2684	216	23	4a	4a	NUM
admet-2684	216	24	.	.	PUNCT
admet-2684	217	1	compared	compare	VERB
admet-2684	217	2	to	to	ADP
admet-2684	217	3	the	the	DET
admet-2684	217	4	control	control	NOUN
admet-2684	217	5	sample	sample	NOUN
admet-2684	217	6	,	,	PUNCT
admet-2684	217	7	agent	agent	NOUN
admet-2684	217	8	10	10	NUM
admet-2684	217	9	caused	cause	VERB
admet-2684	217	10	downregulation	downregulation	NOUN
admet-2684	217	11	of	of	ADP
admet-2684	217	12	only	only	ADV
admet-2684	217	13	one	one	NUM
admet-2684	217	14	protein	protein	NOUN
admet-2684	217	15	–	–	PUNCT
admet-2684	217	16	uncharacterized	uncharacterized	ADJ
admet-2684	217	17	oxidoreductase	oxidoreductase	NOUN
admet-2684	217	18	sausa300_2422	sausa300_2422	NOUN
admet-2684	217	19	(	(	PUNCT
admet-2684	217	20	q2fe2	q2fe2	NOUN
admet-2684	217	21	)	)	PUNCT
admet-2684	217	22	,	,	PUNCT
admet-2684	217	23	which	which	PRON
admet-2684	217	24	was	be	AUX
admet-2684	217	25	also	also	ADV
admet-2684	217	26	more	more	ADV
admet-2684	217	27	significantly	significantly	ADV
admet-2684	217	28	downregulated	downregulate	VERB
admet-2684	217	29	by	by	ADP
admet-2684	217	30	inactive	inactive	ADJ
admet-2684	217	31	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	PROPN
admet-2684	217	32	l.	l.	PROPN
admet-2684	217	33	vrablova	vrablova	PROPN
admet-2684	217	34	et	et	PROPN
admet-2684	217	35	al	al	PROPN
admet-2684	217	36	.	.	PROPN
admet-2684	217	37	admet	admet	PROPN
admet-2684	217	38	&	&	CCONJ
admet-2684	217	39	dmpk	dmpk	PROPN
admet-2684	217	40	13(2	13(2	PROPN
admet-2684	217	41	)	)	PUNCT
admet-2684	217	42	(	(	PUNCT
admet-2684	217	43	2025	2025	NUM
admet-2684	217	44	)	)	PUNCT
admet-2684	217	45	2684	2684	NUM
admet-2684	217	46	10	10	NUM
admet-2684	217	47	compound	compound	NOUN
admet-2684	217	48	9	9	NUM
admet-2684	217	49	.	.	PUNCT
admet-2684	218	1	in	in	ADP
admet-2684	218	2	addition	addition	NOUN
admet-2684	218	3	,	,	PUNCT
admet-2684	218	4	compound	compound	NOUN
admet-2684	218	5	9	9	NUM
admet-2684	218	6	caused	cause	VERB
admet-2684	218	7	a	a	DET
admet-2684	218	8	decrease	decrease	NOUN
admet-2684	218	9	in	in	ADP
admet-2684	218	10	the	the	DET
admet-2684	218	11	expression	expression	NOUN
admet-2684	218	12	of	of	ADP
admet-2684	218	13	four	four	NUM
admet-2684	218	14	other	other	ADJ
admet-2684	218	15	proteins	protein	NOUN
admet-2684	218	16	(	(	PUNCT
admet-2684	218	17	bottom	bottom	NOUN
admet-2684	218	18	of	of	ADP
admet-2684	218	19	the	the	DET
admet-2684	218	20	heatmap	heatmap	NOUN
admet-2684	218	21	):	):	PUNCT
admet-2684	218	22	large	large	ADJ
admet-2684	218	23	ribosomal	ribosomal	NOUN
admet-2684	218	24	subunit	subunit	NOUN
admet-2684	218	25	protein	protein	NOUN
admet-2684	218	26	ul2	ul2	VERB
admet-2684	218	27	(	(	PUNCT
admet-2684	218	28	a5iv31	a5iv31	ADJ
admet-2684	218	29	)	)	PUNCT
admet-2684	218	30	,	,	PUNCT
admet-2684	218	31	uncharacterized	uncharacterized	ADJ
admet-2684	218	32	lipoprotein	lipoprotein	ADJ
admet-2684	218	33	sas2259	sas2259	NOUN
admet-2684	218	34	(	(	PUNCT
admet-2684	218	35	q6g6v2	q6g6v2	PROPN
admet-2684	218	36	)	)	PUNCT
admet-2684	218	37	,	,	PUNCT
admet-2684	218	38	dihydroneopterin	dihydroneopterin	NOUN
admet-2684	218	39	aldolase	aldolase	NOUN
admet-2684	218	40	(	(	PUNCT
admet-2684	218	41	q5hrn9	q5hrn9	ADJ
admet-2684	218	42	)	)	PUNCT
admet-2684	218	43	,	,	PUNCT
admet-2684	218	44	and	and	CCONJ
admet-2684	218	45	aminoacyltransferase	aminoacyltransferase	PROPN
admet-2684	218	46	femb	femb	PROPN
admet-2684	218	47	(	(	PUNCT
admet-2684	218	48	q5hpg5	q5hpg5	NOUN
admet-2684	218	49	)	)	PUNCT
admet-2684	218	50	.	.	PUNCT
admet-2684	219	1	figure	figure	VERB
admet-2684	219	2	4	4	NUM
admet-2684	219	3	.	.	PUNCT
admet-2684	219	4	s.	s.	PROPN
admet-2684	219	5	aureus	aureus	PROPN
admet-2684	219	6	heatmap	heatmap	NOUN
admet-2684	219	7	comparing	compare	VERB
admet-2684	219	8	proteomic	proteomic	ADJ
admet-2684	219	9	profiles	profile	NOUN
admet-2684	219	10	in	in	ADP
admet-2684	219	11	control	control	NOUN
admet-2684	219	12	sample	sample	NOUN
admet-2684	219	13	(	(	PUNCT
admet-2684	219	14	cn	cn	PROPN
admet-2684	219	15	)	)	PUNCT
admet-2684	219	16	,	,	PUNCT
admet-2684	219	17	sample	sample	NOUN
admet-2684	219	18	with	with	ADP
admet-2684	219	19	antibacterially	antibacterially	ADV
admet-2684	219	20	inactive	inactive	ADJ
admet-2684	219	21	compound	compound	NOUN
admet-2684	219	22	9	9	NUM
admet-2684	219	23	and	and	CCONJ
admet-2684	219	24	sample	sample	NOUN
admet-2684	219	25	with	with	ADP
admet-2684	219	26	antibacterially	antibacterially	ADV
admet-2684	219	27	active	active	ADJ
admet-2684	219	28	agent	agent	NOUN
admet-2684	219	29	10	10	NUM
admet-2684	219	30	(	(	PUNCT
admet-2684	219	31	a	a	NOUN
admet-2684	219	32	)	)	PUNCT
admet-2684	219	33	,	,	PUNCT
admet-2684	219	34	and	and	CCONJ
admet-2684	219	35	mrsa	mrsa	NOUN
admet-2684	219	36	heatmap	heatmap	NOUN
admet-2684	219	37	comparing	compare	VERB
admet-2684	219	38	protein	protein	NOUN
admet-2684	219	39	expression	expression	NOUN
admet-2684	219	40	in	in	ADP
admet-2684	219	41	control	control	NOUN
admet-2684	219	42	sample	sample	NOUN
admet-2684	219	43	(	(	PUNCT
admet-2684	219	44	cn	cn	PROPN
admet-2684	219	45	)	)	PUNCT
admet-2684	219	46	,	,	PUNCT
admet-2684	219	47	sample	sample	NOUN
admet-2684	219	48	with	with	ADP
admet-2684	219	49	inactive	inactive	ADJ
admet-2684	219	50	compound	compound	NOUN
admet-2684	219	51	9	9	NUM
admet-2684	219	52	and	and	CCONJ
admet-2684	219	53	sample	sample	NOUN
admet-2684	219	54	with	with	ADP
admet-2684	219	55	active	active	ADJ
admet-2684	219	56	agent	agent	NOUN
admet-2684	219	57	10	10	NUM
admet-2684	219	58	(	(	PUNCT
admet-2684	219	59	b	b	NOUN
admet-2684	219	60	)	)	PUNCT
admet-2684	219	61	the	the	DET
admet-2684	219	62	volcano	volcano	NOUN
admet-2684	219	63	plot	plot	NOUN
admet-2684	219	64	of	of	ADP
admet-2684	219	65	expression	expression	NOUN
admet-2684	219	66	changes	change	NOUN
admet-2684	219	67	between	between	ADP
admet-2684	219	68	samples	sample	NOUN
admet-2684	219	69	shows	show	VERB
admet-2684	219	70	several	several	ADJ
admet-2684	219	71	of	of	ADP
admet-2684	219	72	the	the	DET
admet-2684	219	73	most	most	ADV
admet-2684	219	74	significant	significant	ADJ
admet-2684	219	75	differences	difference	NOUN
admet-2684	219	76	between	between	ADP
admet-2684	219	77	the	the	DET
admet-2684	219	78	control	control	NOUN
admet-2684	219	79	and	and	CCONJ
admet-2684	219	80	samples	sample	NOUN
admet-2684	219	81	9	9	NUM
admet-2684	219	82	and	and	CCONJ
admet-2684	219	83	10	10	NUM
admet-2684	219	84	.	.	PUNCT
admet-2684	219	85	inactive	inactive	ADJ
admet-2684	219	86	compound	compound	NOUN
admet-2684	219	87	9	9	NUM
admet-2684	219	88	caused	cause	VERB
admet-2684	219	89	downregulation	downregulation	NOUN
admet-2684	219	90	of	of	ADP
admet-2684	219	91	significantly	significantly	ADV
admet-2684	219	92	more	more	ADJ
admet-2684	219	93	proteins	protein	NOUN
admet-2684	219	94	(	(	PUNCT
admet-2684	219	95	figure	figure	NOUN
admet-2684	219	96	5a	5a	NUM
admet-2684	219	97	)	)	PUNCT
admet-2684	219	98	compared	compare	VERB
admet-2684	219	99	to	to	ADP
admet-2684	219	100	active	active	ADJ
admet-2684	219	101	agent	agent	NOUN
admet-2684	219	102	10	10	NUM
admet-2684	219	103	(	(	PUNCT
admet-2684	219	104	figure	figure	NOUN
admet-2684	219	105	5c	5c	NUM
admet-2684	219	106	)	)	PUNCT
admet-2684	219	107	.	.	PUNCT
admet-2684	220	1	when	when	SCONJ
admet-2684	220	2	comparing	compare	VERB
admet-2684	220	3	the	the	DET
admet-2684	220	4	scales	scale	NOUN
admet-2684	220	5	on	on	ADP
admet-2684	220	6	the	the	DET
admet-2684	220	7	x	x	NOUN
admet-2684	220	8	-	-	NOUN
admet-2684	220	9	axis	axis	ADJ
admet-2684	220	10	,	,	PUNCT
admet-2684	220	11	it	it	PRON
admet-2684	220	12	is	be	AUX
admet-2684	220	13	clear	clear	ADJ
admet-2684	220	14	that	that	SCONJ
admet-2684	220	15	the	the	DET
admet-2684	220	16	proteins	protein	NOUN
admet-2684	220	17	in	in	ADP
admet-2684	220	18	figure	figure	NOUN
admet-2684	220	19	5a	5a	NUM
admet-2684	220	20	show	show	NOUN
admet-2684	220	21	several	several	ADJ
admet-2684	220	22	times	time	NOUN
admet-2684	220	23	greater	great	ADJ
admet-2684	220	24	changes	change	NOUN
admet-2684	220	25	in	in	ADP
admet-2684	220	26	expression	expression	NOUN
admet-2684	220	27	or	or	CCONJ
admet-2684	220	28	inhibition	inhibition	NOUN
admet-2684	220	29	,	,	PUNCT
admet-2684	220	30	respectively	respectively	ADV
admet-2684	220	31	,	,	PUNCT
admet-2684	220	32	than	than	ADP
admet-2684	220	33	those	those	PRON
admet-2684	220	34	in	in	ADP
admet-2684	220	35	figure	figure	NOUN
admet-2684	220	36	5c	5c	NOUN
admet-2684	220	37	.	.	PUNCT
admet-2684	221	1	most	most	ADJ
admet-2684	221	2	of	of	ADP
admet-2684	221	3	the	the	DET
admet-2684	221	4	proteins	protein	NOUN
admet-2684	221	5	that	that	PRON
admet-2684	221	6	were	be	AUX
admet-2684	221	7	affected	affect	VERB
admet-2684	221	8	by	by	ADP
admet-2684	221	9	compound	compound	NOUN
admet-2684	221	10	9	9	NUM
admet-2684	221	11	are	be	AUX
admet-2684	221	12	located	locate	VERB
admet-2684	221	13	in	in	ADP
admet-2684	221	14	the	the	DET
admet-2684	221	15	region	region	NOUN
admet-2684	221	16	of	of	ADP
admet-2684	221	17	the	the	DET
admet-2684	221	18	graph	graph	NOUN
admet-2684	221	19	,	,	PUNCT
admet-2684	221	20	showing	show	VERB
admet-2684	221	21	high	high	ADJ
admet-2684	221	22	statistical	statistical	ADJ
admet-2684	221	23	significance	significance	NOUN
admet-2684	221	24	,	,	PUNCT
admet-2684	221	25	while	while	SCONJ
admet-2684	221	26	the	the	DET
admet-2684	221	27	proteins	protein	NOUN
admet-2684	221	28	affected	affect	VERB
admet-2684	221	29	by	by	ADP
admet-2684	221	30	the	the	DET
admet-2684	221	31	effect	effect	NOUN
admet-2684	221	32	of	of	ADP
admet-2684	221	33	compound	compound	NOUN
admet-2684	221	34	10	10	NUM
admet-2684	221	35	are	be	AUX
admet-2684	221	36	seen	see	VERB
admet-2684	221	37	in	in	ADP
admet-2684	221	38	the	the	DET
admet-2684	221	39	bottom	bottom	ADJ
admet-2684	221	40	parts	part	NOUN
admet-2684	221	41	of	of	ADP
admet-2684	221	42	the	the	DET
admet-2684	221	43	graph	graph	NOUN
admet-2684	221	44	.	.	PUNCT
admet-2684	222	1	it	it	PRON
admet-2684	222	2	is	be	AUX
admet-2684	222	3	important	important	ADJ
admet-2684	222	4	to	to	PART
admet-2684	222	5	note	note	VERB
admet-2684	222	6	that	that	SCONJ
admet-2684	222	7	when	when	SCONJ
admet-2684	222	8	compared	compare	VERB
admet-2684	222	9	to	to	ADP
admet-2684	222	10	the	the	DET
admet-2684	222	11	heatmap	heatmap	NOUN
admet-2684	222	12	(	(	PUNCT
admet-2684	222	13	figure	figure	NOUN
admet-2684	222	14	4a	4a	NOUN
admet-2684	222	15	)	)	PUNCT
admet-2684	222	16	showing	show	VERB
admet-2684	222	17	the	the	DET
admet-2684	222	18	same	same	ADJ
admet-2684	222	19	compounds	compound	NOUN
admet-2684	222	20	,	,	PUNCT
admet-2684	222	21	four	four	NUM
admet-2684	222	22	significant	significant	ADJ
admet-2684	222	23	proteins	protein	NOUN
admet-2684	222	24	were	be	AUX
admet-2684	222	25	identified	identify	VERB
admet-2684	222	26	.	.	PUNCT
admet-2684	223	1	the	the	DET
admet-2684	223	2	volcano	volcano	NOUN
admet-2684	223	3	plot	plot	NOUN
admet-2684	223	4	shows	show	VERB
admet-2684	223	5	that	that	SCONJ
admet-2684	223	6	of	of	ADP
admet-2684	223	7	these	these	DET
admet-2684	223	8	proteins	protein	NOUN
admet-2684	223	9	,	,	PUNCT
admet-2684	223	10	only	only	ADV
admet-2684	223	11	the	the	DET
admet-2684	223	12	atp	atp	NOUN
admet-2684	223	13	-	-	PUNCT
admet-2684	223	14	dependent	dependent	ADJ
admet-2684	223	15	protease	protease	NOUN
admet-2684	223	16	atpase	atpase	NOUN
admet-2684	223	17	subunit	subunit	NOUN
admet-2684	223	18	hslu	hslu	NOUN
admet-2684	223	19	(	(	PUNCT
admet-2684	223	20	q5hpt8	q5hpt8	X
admet-2684	223	21	)	)	PUNCT
admet-2684	223	22	shows	show	VERB
admet-2684	223	23	the	the	DET
admet-2684	223	24	most	most	ADV
admet-2684	223	25	significant	significant	ADJ
admet-2684	223	26	change	change	NOUN
admet-2684	223	27	.	.	PUNCT
admet-2684	224	1	the	the	DET
admet-2684	224	2	others	other	NOUN
admet-2684	224	3	were	be	AUX
admet-2684	224	4	downregulated	downregulate	VERB
admet-2684	224	5	but	but	CCONJ
admet-2684	224	6	not	not	PART
admet-2684	224	7	significantly	significantly	ADV
admet-2684	224	8	compared	compare	VERB
admet-2684	224	9	to	to	ADP
admet-2684	224	10	the	the	DET
admet-2684	224	11	native	native	ADJ
admet-2684	224	12	state	state	NOUN
admet-2684	224	13	of	of	ADP
admet-2684	224	14	the	the	DET
admet-2684	224	15	proteins	protein	NOUN
admet-2684	224	16	in	in	ADP
admet-2684	224	17	the	the	DET
admet-2684	224	18	control	control	NOUN
admet-2684	224	19	sample	sample	NOUN
admet-2684	224	20	of	of	ADP
admet-2684	224	21	s.	s.	PROPN
admet-2684	224	22	aureus	aureus	PROPN
admet-2684	224	23	.	.	PUNCT
admet-2684	225	1	the	the	DET
admet-2684	225	2	mrsa	mrsa	NOUN
admet-2684	225	3	samples	sample	NOUN
admet-2684	225	4	shown	show	VERB
admet-2684	225	5	in	in	ADP
admet-2684	225	6	figure	figure	NOUN
admet-2684	225	7	5b	5b	NUM
admet-2684	225	8	(	(	PUNCT
admet-2684	225	9	control	control	NOUN
admet-2684	225	10	vs.	vs.	ADP
admet-2684	225	11	9	9	NUM
admet-2684	225	12	)	)	PUNCT
admet-2684	225	13	and	and	CCONJ
admet-2684	225	14	figure	figure	VERB
admet-2684	225	15	5d	5d	PROPN
admet-2684	225	16	(	(	PUNCT
admet-2684	225	17	control	control	NOUN
admet-2684	225	18	vs.	vs.	ADP
admet-2684	225	19	10	10	NUM
admet-2684	225	20	)	)	PUNCT
admet-2684	225	21	show	show	VERB
admet-2684	225	22	a	a	DET
admet-2684	225	23	smaller	small	ADJ
admet-2684	225	24	difference	difference	NOUN
admet-2684	225	25	in	in	ADP
admet-2684	225	26	the	the	DET
admet-2684	225	27	extent	extent	NOUN
admet-2684	225	28	of	of	ADP
admet-2684	225	29	changes	change	NOUN
admet-2684	225	30	compared	compare	VERB
admet-2684	225	31	to	to	ADP
admet-2684	225	32	the	the	DET
admet-2684	225	33	volcano	volcano	NOUN
admet-2684	225	34	plots	plot	VERB
admet-2684	225	35	in	in	ADP
admet-2684	225	36	figures	figure	NOUN
admet-2684	225	37	5a	5a	NUM
admet-2684	225	38	and	and	CCONJ
admet-2684	225	39	5c	5c	NUM
admet-2684	225	40	.	.	PUNCT
admet-2684	226	1	at	at	ADP
admet-2684	226	2	the	the	DET
admet-2684	226	3	same	same	ADJ
admet-2684	226	4	time	time	NOUN
admet-2684	226	5	,	,	PUNCT
admet-2684	226	6	the	the	DET
admet-2684	226	7	mrsa	mrsa	NOUN
admet-2684	226	8	proteome	proteome	PROPN
admet-2684	226	9	was	be	AUX
admet-2684	226	10	significantly	significantly	ADV
admet-2684	226	11	more	more	ADV
admet-2684	226	12	affected	affect	VERB
admet-2684	226	13	by	by	ADP
admet-2684	226	14	compound	compound	NOUN
admet-2684	226	15	9	9	NUM
admet-2684	226	16	than	than	ADP
admet-2684	226	17	by	by	ADP
admet-2684	226	18	agent	agent	NOUN
admet-2684	226	19	10	10	NUM
admet-2684	226	20	.	.	PUNCT
admet-2684	227	1	from	from	ADP
admet-2684	227	2	the	the	DET
admet-2684	227	3	heatmap	heatmap	NOUN
admet-2684	227	4	(	(	PUNCT
admet-2684	227	5	figure	figure	NOUN
admet-2684	227	6	4b	4b	PROPN
admet-2684	227	7	)	)	PUNCT
admet-2684	227	8	correlated	correlate	VERB
admet-2684	227	9	with	with	ADP
admet-2684	227	10	the	the	DET
admet-2684	227	11	given	give	VERB
admet-2684	227	12	compounds	compound	NOUN
admet-2684	227	13	,	,	PUNCT
admet-2684	227	14	only	only	ADV
admet-2684	227	15	the	the	DET
admet-2684	227	16	admet	admet	PROPN
admet-2684	227	17	&	&	CCONJ
admet-2684	227	18	dmpk	dmpk	PROPN
admet-2684	227	19	13(2	13(2	PROPN
admet-2684	227	20	)	)	PUNCT
admet-2684	227	21	(	(	PUNCT
admet-2684	227	22	2025	2025	NUM
admet-2684	227	23	)	)	PUNCT
admet-2684	227	24	2684	2684	NUM
admet-2684	227	25	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	227	26	effect	effect	NOUN
admet-2684	227	27	of	of	ADP
admet-2684	227	28	chlorinated	chlorinate	VERB
admet-2684	227	29	1	1	NUM
admet-2684	227	30	-	-	PUNCT
admet-2684	227	31	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	227	32	-	-	PUNCT
admet-2684	227	33	carboxanilides	carboxanilide	NOUN
admet-2684	227	34	doi	doi	NOUN
admet-2684	227	35	:	:	PUNCT
admet-2684	227	36	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	227	37	11	11	NUM
admet-2684	227	38	protein	protein	NOUN
admet-2684	227	39	uncharacterized	uncharacterized	ADJ
admet-2684	227	40	oxidoreductase	oxidoreductase	NOUN
admet-2684	227	41	sausa300_2422	sausa300_2422	NOUN
admet-2684	227	42	(	(	PUNCT
admet-2684	227	43	q2fe2	q2fe2	NOUN
admet-2684	227	44	)	)	PUNCT
admet-2684	227	45	was	be	AUX
admet-2684	227	46	identified	identify	VERB
admet-2684	227	47	as	as	ADP
admet-2684	227	48	downregulated	downregulate	VERB
admet-2684	227	49	,	,	PUNCT
admet-2684	227	50	but	but	CCONJ
admet-2684	227	51	its	its	PRON
admet-2684	227	52	change	change	NOUN
admet-2684	227	53	was	be	AUX
admet-2684	227	54	assessed	assess	VERB
admet-2684	227	55	as	as	ADP
admet-2684	227	56	insufficiently	insufficiently	ADV
admet-2684	227	57	significant	significant	ADJ
admet-2684	227	58	(	(	PUNCT
admet-2684	227	59	figure	figure	NOUN
admet-2684	227	60	5d	5d	NUM
admet-2684	227	61	)	)	PUNCT
admet-2684	227	62	.	.	PUNCT
admet-2684	228	1	figure	figure	VERB
admet-2684	228	2	5	5	NUM
admet-2684	228	3	.	.	X
admet-2684	228	4	volcano	volcano	NOUN
admet-2684	228	5	plot	plot	NOUN
admet-2684	228	6	of	of	ADP
admet-2684	228	7	fold	fold	ADJ
admet-2684	228	8	changes	change	NOUN
admet-2684	228	9	(	(	PUNCT
admet-2684	228	10	fc	fc	INTJ
admet-2684	228	11	)	)	PUNCT
admet-2684	228	12	in	in	ADP
admet-2684	228	13	protein	protein	NOUN
admet-2684	228	14	expression	expression	NOUN
admet-2684	228	15	in	in	ADP
admet-2684	228	16	s.	s.	PROPN
admet-2684	228	17	aureus	aureus	PROPN
admet-2684	228	18	between	between	ADP
admet-2684	228	19	control	control	NOUN
admet-2684	228	20	sample	sample	NOUN
admet-2684	228	21	and	and	CCONJ
admet-2684	228	22	compound	compound	VERB
admet-2684	228	23	9	9	NUM
admet-2684	228	24	(	(	PUNCT
admet-2684	228	25	a	a	NOUN
admet-2684	228	26	)	)	PUNCT
admet-2684	228	27	,	,	PUNCT
admet-2684	228	28	between	between	ADP
admet-2684	228	29	control	control	NOUN
admet-2684	228	30	and	and	CCONJ
admet-2684	228	31	agent	agent	NOUN
admet-2684	228	32	10	10	NUM
admet-2684	228	33	(	(	PUNCT
admet-2684	228	34	c	c	NOUN
admet-2684	228	35	)	)	PUNCT
admet-2684	228	36	,	,	PUNCT
admet-2684	228	37	changes	change	NOUN
admet-2684	228	38	in	in	ADP
admet-2684	228	39	expression	expression	NOUN
admet-2684	228	40	in	in	ADP
admet-2684	228	41	mrsa	mrsa	NOUN
admet-2684	228	42	between	between	ADP
admet-2684	228	43	control	control	NOUN
admet-2684	228	44	and	and	CCONJ
admet-2684	228	45	compound	compound	NOUN
admet-2684	228	46	9	9	NUM
admet-2684	228	47	(	(	PUNCT
admet-2684	228	48	b	b	NOUN
admet-2684	228	49	)	)	PUNCT
admet-2684	228	50	,	,	PUNCT
admet-2684	228	51	between	between	ADP
admet-2684	228	52	control	control	NOUN
admet-2684	228	53	and	and	CCONJ
admet-2684	228	54	agent	agent	NOUN
admet-2684	228	55	10	10	NUM
admet-2684	228	56	(	(	PUNCT
admet-2684	228	57	d	d	X
admet-2684	228	58	)	)	PUNCT
admet-2684	228	59	the	the	DET
admet-2684	228	60	proteins	protein	NOUN
admet-2684	228	61	that	that	PRON
admet-2684	228	62	were	be	AUX
admet-2684	228	63	found	find	VERB
admet-2684	228	64	to	to	PART
admet-2684	228	65	be	be	AUX
admet-2684	228	66	downregulated	downregulate	VERB
admet-2684	228	67	after	after	ADP
admet-2684	228	68	exposure	exposure	NOUN
admet-2684	228	69	to	to	ADP
admet-2684	228	70	active	active	ADJ
admet-2684	228	71	agent	agent	NOUN
admet-2684	228	72	10	10	NUM
admet-2684	228	73	and	and	CCONJ
admet-2684	228	74	their	their	PRON
admet-2684	228	75	significance	significance	NOUN
admet-2684	228	76	/	/	SYM
admet-2684	228	77	function	function	NOUN
admet-2684	228	78	for	for	ADP
admet-2684	228	79	bacterial	bacterial	ADJ
admet-2684	228	80	viability	viability	NOUN
admet-2684	228	81	are	be	AUX
admet-2684	228	82	listed	list	VERB
admet-2684	228	83	in	in	ADP
admet-2684	228	84	table	table	NOUN
admet-2684	228	85	4	4	NUM
admet-2684	228	86	.	.	PUNCT
admet-2684	228	87	table	table	NOUN
admet-2684	228	88	4	4	NUM
admet-2684	228	89	.	.	PUNCT
admet-2684	228	90	downregulated	downregulate	VERB
admet-2684	228	91	proteins	protein	NOUN
admet-2684	228	92	detected	detect	VERB
admet-2684	228	93	after	after	ADP
admet-2684	228	94	treatment	treatment	NOUN
admet-2684	228	95	with	with	ADP
admet-2684	228	96	active	active	ADJ
admet-2684	228	97	agent	agent	NOUN
admet-2684	228	98	10	10	NUM
admet-2684	228	99	and	and	CCONJ
admet-2684	228	100	their	their	PRON
admet-2684	228	101	functions	function	NOUN
admet-2684	228	102	in	in	ADP
admet-2684	228	103	bacteria	bacteria	NOUN
admet-2684	228	104	.	.	PUNCT
admet-2684	229	1	protein	protein	NOUN
admet-2684	229	2	function	function	VERB
admet-2684	229	3	probable	probable	ADJ
admet-2684	229	4	tautomerase	tautomerase	NOUN
admet-2684	229	5	sav1363	sav1363	NOUN
admet-2684	229	6	(	(	PUNCT
admet-2684	229	7	p67526	p67526	NOUN
admet-2684	229	8	)	)	PUNCT
admet-2684	229	9	protein	protein	NOUN
admet-2684	229	10	involved	involve	VERB
admet-2684	229	11	in	in	ADP
admet-2684	229	12	processes	process	NOUN
admet-2684	229	13	mediating	mediate	VERB
admet-2684	229	14	tautomerization	tautomerization	NOUN
admet-2684	229	15	,	,	PUNCT
admet-2684	229	16	microbial	microbial	ADJ
admet-2684	229	17	metabolism	metabolism	NOUN
admet-2684	229	18	in	in	ADP
admet-2684	229	19	various	various	ADJ
admet-2684	229	20	environments	environment	NOUN
admet-2684	229	21	,	,	PUNCT
admet-2684	229	22	and	and	CCONJ
admet-2684	229	23	degradation	degradation	NOUN
admet-2684	229	24	/	/	SYM
admet-2684	229	25	detoxification	detoxification	NOUN
admet-2684	229	26	of	of	ADP
admet-2684	229	27	aromatic	aromatic	ADJ
admet-2684	229	28	compounds	compound	NOUN
admet-2684	229	29	(	(	PUNCT
admet-2684	229	30	xenobiotics	xenobiotic	NOUN
admet-2684	229	31	)	)	PUNCT
admet-2684	230	1	[	[	X
admet-2684	230	2	64,76	64,76	NUM
admet-2684	230	3	]	]	PUNCT
admet-2684	230	4	.	.	PUNCT
admet-2684	231	1	ribonuclease	ribonuclease	NOUN
admet-2684	231	2	j2	j2	NOUN
admet-2684	231	3	(	(	PUNCT
admet-2684	231	4	q5hpr6	q5hpr6	NOUN
admet-2684	231	5	)	)	PUNCT
admet-2684	231	6	metalloprotein	metalloprotein	NOUN
admet-2684	231	7	(	(	PUNCT
admet-2684	231	8	cofactor	cofactor	NOUN
admet-2684	231	9	two	two	NUM
admet-2684	231	10	zn2⁺	zn2⁺	PROPN
admet-2684	231	11	ions	ion	NOUN
admet-2684	231	12	)	)	PUNCT
admet-2684	231	13	exhibiting	exhibit	VERB
admet-2684	231	14	5'-3	5'-3	NOUN
admet-2684	231	15	'	'	PART
admet-2684	231	16	exonuclease	exonuclease	NOUN
admet-2684	231	17	and	and	CCONJ
admet-2684	231	18	endonuclease	endonuclease	NOUN
admet-2684	231	19	activity	activity	NOUN
admet-2684	231	20	,	,	PUNCT
admet-2684	231	21	respectively	respectively	ADV
admet-2684	231	22	,	,	PUNCT
admet-2684	231	23	which	which	PRON
admet-2684	231	24	plays	play	VERB
admet-2684	231	25	a	a	DET
admet-2684	231	26	role	role	NOUN
admet-2684	231	27	in	in	ADP
admet-2684	231	28	rrna	rrna	NOUN
admet-2684	231	29	maturation	maturation	NOUN
admet-2684	231	30	.	.	PUNCT
admet-2684	232	1	it	it	PRON
admet-2684	232	2	is	be	AUX
admet-2684	232	3	also	also	ADV
admet-2684	232	4	involved	involve	VERB
admet-2684	232	5	in	in	ADP
admet-2684	232	6	mrna	mrna	PROPN
admet-2684	232	7	synthesis	synthesis	NOUN
admet-2684	232	8	and/or	and/or	CCONJ
admet-2684	232	9	degradation	degradation	NOUN
admet-2684	232	10	.	.	PUNCT
admet-2684	233	1	it	it	PRON
admet-2684	233	2	affects	affect	VERB
admet-2684	233	3	bacterial	bacterial	ADJ
admet-2684	233	4	viability	viability	NOUN
admet-2684	233	5	through	through	ADP
admet-2684	233	6	the	the	DET
admet-2684	233	7	regulation	regulation	NOUN
admet-2684	233	8	of	of	ADP
admet-2684	233	9	gene	gene	NOUN
admet-2684	233	10	expression	expression	NOUN
admet-2684	233	11	at	at	ADP
admet-2684	233	12	the	the	DET
admet-2684	233	13	rna	rna	NOUN
admet-2684	233	14	level	level	NOUN
admet-2684	233	15	[	[	X
admet-2684	233	16	64	64	NUM
admet-2684	233	17	]	]	PUNCT
admet-2684	233	18	.	.	PUNCT
admet-2684	234	1	atp	atp	PROPN
admet-2684	234	2	-	-	PUNCT
admet-2684	234	3	dependent	dependent	ADJ
admet-2684	234	4	protease	protease	NOUN
admet-2684	234	5	atpase	atpase	NOUN
admet-2684	234	6	subunit	subunit	NOUN
admet-2684	234	7	hslu	hslu	NOUN
admet-2684	234	8	(	(	PUNCT
admet-2684	234	9	q5hpt8	q5hpt8	X
admet-2684	234	10	)	)	PUNCT
admet-2684	234	11	atpase	atpase	NOUN
admet-2684	234	12	subunit	subunit	NOUN
admet-2684	234	13	of	of	ADP
admet-2684	234	14	the	the	DET
admet-2684	234	15	proteasome	proteasome	NOUN
admet-2684	234	16	-	-	PUNCT
admet-2684	234	17	like	like	ADJ
admet-2684	234	18	degradation	degradation	NOUN
admet-2684	234	19	complex	complex	NOUN
admet-2684	234	20	with	with	ADP
admet-2684	234	21	chaperone	chaperone	NOUN
admet-2684	234	22	activity	activity	NOUN
admet-2684	234	23	.	.	PUNCT
admet-2684	235	1	it	it	PRON
admet-2684	235	2	is	be	AUX
admet-2684	235	3	involved	involve	VERB
admet-2684	235	4	in	in	ADP
admet-2684	235	5	the	the	DET
admet-2684	235	6	vital	vital	ADJ
admet-2684	235	7	function	function	NOUN
admet-2684	235	8	of	of	ADP
admet-2684	235	9	ridding	rid	VERB
admet-2684	235	10	the	the	DET
admet-2684	235	11	cell	cell	NOUN
admet-2684	235	12	of	of	ADP
admet-2684	235	13	damaged	damage	VERB
admet-2684	235	14	,	,	PUNCT
admet-2684	235	15	misfolded	misfolded	ADJ
admet-2684	235	16	or	or	CCONJ
admet-2684	235	17	abnormal	abnormal	ADJ
admet-2684	235	18	proteins	protein	NOUN
admet-2684	235	19	(	(	PUNCT
admet-2684	235	20	e.g.	e.g.	ADV
admet-2684	235	21	due	due	ADJ
admet-2684	235	22	to	to	ADP
admet-2684	235	23	stress	stress	NOUN
admet-2684	235	24	induced	induce	VERB
admet-2684	235	25	by	by	ADP
admet-2684	235	26	antibiotic	antibiotic	ADJ
admet-2684	235	27	treatment	treatment	NOUN
admet-2684	235	28	)	)	PUNCT
admet-2684	235	29	as	as	ADV
admet-2684	235	30	well	well	ADV
admet-2684	235	31	as	as	ADP
admet-2684	235	32	controlling	control	VERB
admet-2684	235	33	the	the	DET
admet-2684	235	34	levels	level	NOUN
admet-2684	235	35	of	of	ADP
admet-2684	235	36	regulatory	regulatory	ADJ
admet-2684	235	37	proteins	protein	NOUN
admet-2684	235	38	[	[	X
admet-2684	235	39	64,77	64,77	NOUN
admet-2684	235	40	]	]	PUNCT
admet-2684	235	41	.	.	PUNCT
admet-2684	236	1	adenylosuccinate	adenylosuccinate	ADJ
admet-2684	236	2	synthetase	synthetase	NOUN
admet-2684	236	3	(	(	PUNCT
admet-2684	236	4	p65884	p65884	NOUN
admet-2684	236	5	)	)	PUNCT
admet-2684	236	6	key	key	ADJ
admet-2684	236	7	role	role	NOUN
admet-2684	236	8	in	in	ADP
admet-2684	236	9	the	the	DET
admet-2684	236	10	de	de	X
admet-2684	236	11	novo	novo	NOUN
admet-2684	236	12	biosynthetic	biosynthetic	ADJ
admet-2684	236	13	pathway	pathway	NOUN
admet-2684	236	14	of	of	ADP
admet-2684	236	15	purine	purine	NOUN
admet-2684	236	16	nucleotides	nucleotide	NOUN
admet-2684	236	17	essential	essential	ADJ
admet-2684	236	18	for	for	ADP
admet-2684	236	19	bacteria	bacteria	NOUN
admet-2684	236	20	(	(	PUNCT
admet-2684	236	21	basic	basic	ADJ
admet-2684	236	22	cellular	cellular	ADJ
admet-2684	236	23	processes	process	NOUN
admet-2684	236	24	,	,	PUNCT
admet-2684	236	25	dna	dna	PROPN
admet-2684	236	26	/	/	SYM
admet-2684	236	27	rna	rna	NOUN
admet-2684	236	28	synthesis	synthesis	NOUN
admet-2684	236	29	and	and	CCONJ
admet-2684	236	30	energy	energy	NOUN
admet-2684	236	31	metabolism	metabolism	NOUN
admet-2684	236	32	)	)	PUNCT
admet-2684	236	33	.	.	PUNCT
admet-2684	237	1	it	it	PRON
admet-2684	237	2	catalyzes	catalyze	VERB
admet-2684	237	3	the	the	DET
admet-2684	237	4	first	first	ADJ
admet-2684	237	5	key	key	ADJ
admet-2684	237	6	step	step	NOUN
admet-2684	237	7	in	in	ADP
admet-2684	237	8	the	the	DET
admet-2684	237	9	synthesis	synthesis	NOUN
admet-2684	237	10	of	of	ADP
admet-2684	237	11	adenosine	adenosine	ADJ
admet-2684	237	12	monophosphate	monophosphate	NOUN
admet-2684	237	13	(	(	PUNCT
admet-2684	237	14	amp	amp	PROPN
admet-2684	237	15	)	)	PUNCT
admet-2684	237	16	from	from	ADP
admet-2684	237	17	inosine	inosine	NOUN
admet-2684	237	18	monophosphate	monophosphate	NOUN
admet-2684	237	19	(	(	PUNCT
admet-2684	237	20	imp	imp	PROPN
admet-2684	237	21	)	)	PUNCT
admet-2684	237	22	.	.	PUNCT
admet-2684	238	1	it	it	PRON
admet-2684	238	2	requires	require	VERB
admet-2684	238	3	the	the	DET
admet-2684	238	4	presence	presence	NOUN
admet-2684	238	5	of	of	ADP
admet-2684	238	6	mg2⁺	mg2⁺	PROPN
admet-2684	238	7	ions	ion	NOUN
admet-2684	238	8	for	for	ADP
admet-2684	238	9	its	its	PRON
admet-2684	238	10	function	function	NOUN
admet-2684	238	11	[	[	X
admet-2684	238	12	64	64	NUM
admet-2684	238	13	]	]	PUNCT
admet-2684	238	14	.	.	PUNCT
admet-2684	239	1	if	if	SCONJ
admet-2684	239	2	certain	certain	ADJ
admet-2684	239	3	proteins	protein	NOUN
admet-2684	239	4	are	be	AUX
admet-2684	239	5	downregulated	downregulate	VERB
admet-2684	239	6	in	in	ADP
admet-2684	239	7	bacteria	bacteria	NOUN
admet-2684	239	8	even	even	ADV
admet-2684	239	9	after	after	ADP
admet-2684	239	10	treatment	treatment	NOUN
admet-2684	239	11	with	with	ADP
admet-2684	239	12	an	an	DET
admet-2684	239	13	antibacterially	antibacterially	ADV
admet-2684	239	14	inactive	inactive	ADJ
admet-2684	239	15	compound	compound	NOUN
admet-2684	239	16	(	(	PUNCT
admet-2684	239	17	high	high	ADJ
admet-2684	239	18	mic	mic	ADJ
admet-2684	239	19	value	value	NOUN
admet-2684	239	20	)	)	PUNCT
admet-2684	239	21	,	,	PUNCT
admet-2684	239	22	as	as	SCONJ
admet-2684	239	23	observed	observe	VERB
admet-2684	239	24	with	with	ADP
admet-2684	239	25	compound	compound	NOUN
admet-2684	239	26	9	9	NUM
admet-2684	239	27	(	(	PUNCT
admet-2684	239	28	compare	compare	VERB
admet-2684	239	29	770	770	NUM
admet-2684	239	30	µm	µm	ADP
admet-2684	239	31	vs.	vs.	ADP
admet-2684	239	32	0.37	0.37	NUM
admet-2684	239	33	µm	µm	NOUN
admet-2684	239	34	for	for	ADP
admet-2684	239	35	agent	agent	NOUN
admet-2684	239	36	10	10	NUM
admet-2684	239	37	)	)	PUNCT
admet-2684	239	38	,	,	PUNCT
admet-2684	239	39	this	this	PRON
admet-2684	239	40	suggests	suggest	VERB
admet-2684	239	41	that	that	SCONJ
admet-2684	239	42	decreased	decrease	VERB
admet-2684	239	43	expression	expression	NOUN
admet-2684	239	44	of	of	ADP
admet-2684	239	45	these	these	DET
admet-2684	239	46	proteins	protein	NOUN
admet-2684	239	47	does	do	AUX
admet-2684	239	48	not	not	PART
admet-2684	239	49	significantly	significantly	ADV
admet-2684	239	50	impact	impact	VERB
admet-2684	239	51	bacterial	bacterial	ADJ
admet-2684	239	52	growth	growth	NOUN
admet-2684	239	53	.	.	PUNCT
admet-2684	240	1	while	while	SCONJ
admet-2684	240	2	treatment	treatment	NOUN
admet-2684	240	3	with	with	ADP
admet-2684	240	4	antibacterially	antibacterially	ADV
admet-2684	240	5	inactive	inactive	ADJ
admet-2684	240	6	compounds	compound	NOUN
admet-2684	240	7	induces	induce	VERB
admet-2684	240	8	stress	stress	NOUN
admet-2684	240	9	[	[	X
admet-2684	240	10	78	78	NUM
admet-2684	240	11	-	-	SYM
admet-2684	240	12	80	80	NUM
admet-2684	240	13	]	]	PUNCT
admet-2684	240	14	,	,	PUNCT
admet-2684	240	15	it	it	PRON
admet-2684	240	16	also	also	ADV
admet-2684	240	17	triggers	trigger	VERB
admet-2684	240	18	the	the	DET
admet-2684	240	19	expression	expression	NOUN
admet-2684	240	20	(	(	PUNCT
admet-2684	240	21	upregulation	upregulation	NOUN
admet-2684	240	22	)	)	PUNCT
admet-2684	240	23	of	of	ADP
admet-2684	240	24	alternative	alternative	ADJ
admet-2684	240	25	proteins	protein	NOUN
admet-2684	240	26	that	that	PRON
admet-2684	240	27	help	help	VERB
admet-2684	240	28	maintain	maintain	VERB
admet-2684	240	29	bacterial	bacterial	ADJ
admet-2684	240	30	viability	viability	NOUN
admet-2684	240	31	.	.	PUNCT
admet-2684	241	1	consequently	consequently	ADV
admet-2684	241	2	,	,	PUNCT
admet-2684	241	3	inactive	inactive	ADJ
admet-2684	241	4	compound	compound	NOUN
admet-2684	241	5	9	9	NUM
admet-2684	241	6	had	have	VERB
admet-2684	241	7	a	a	DET
admet-2684	241	8	much	much	ADV
admet-2684	241	9	greater	great	ADJ
admet-2684	241	10	impact	impact	NOUN
admet-2684	241	11	on	on	ADP
admet-2684	241	12	the	the	DET
admet-2684	241	13	bacterial	bacterial	ADJ
admet-2684	241	14	proteome	proteome	NOUN
admet-2684	241	15	than	than	ADP
admet-2684	241	16	active	active	ADJ
admet-2684	241	17	agent	agent	NOUN
admet-2684	241	18	10	10	NUM
admet-2684	241	19	.	.	PUNCT
admet-2684	242	1	in	in	ADP
admet-2684	242	2	contrast	contrast	NOUN
admet-2684	242	3	,	,	PUNCT
admet-2684	242	4	the	the	DET
admet-2684	242	5	active	active	ADJ
admet-2684	242	6	agent	agent	NOUN
admet-2684	242	7	10	10	NUM
admet-2684	242	8	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	242	9	l.	l.	PROPN
admet-2684	242	10	vrablova	vrablova	PROPN
admet-2684	242	11	et	et	PROPN
admet-2684	242	12	al	al	PROPN
admet-2684	242	13	.	.	PROPN
admet-2684	242	14	admet	admet	PROPN
admet-2684	242	15	&	&	CCONJ
admet-2684	242	16	dmpk	dmpk	PROPN
admet-2684	242	17	13(2	13(2	PROPN
admet-2684	242	18	)	)	PUNCT
admet-2684	242	19	(	(	PUNCT
admet-2684	242	20	2025	2025	NUM
admet-2684	242	21	)	)	PUNCT
admet-2684	242	22	2684	2684	NUM
admet-2684	242	23	12	12	NUM
admet-2684	242	24	induces	induce	VERB
admet-2684	242	25	fewer	few	ADJ
admet-2684	242	26	proteomic	proteomic	ADJ
admet-2684	242	27	changes	change	NOUN
admet-2684	242	28	(	(	PUNCT
admet-2684	242	29	downregulation	downregulation	NOUN
admet-2684	242	30	)	)	PUNCT
admet-2684	242	31	but	but	CCONJ
admet-2684	242	32	selectively	selectively	ADV
admet-2684	242	33	eliminates	eliminate	VERB
admet-2684	242	34	proteins	protein	NOUN
admet-2684	242	35	essential	essential	ADJ
admet-2684	242	36	for	for	ADP
admet-2684	242	37	bacterial	bacterial	ADJ
admet-2684	242	38	survival	survival	NOUN
admet-2684	242	39	.	.	PUNCT
admet-2684	243	1	conclusions	conclusion	NOUN
admet-2684	243	2	twelve	twelve	NUM
admet-2684	243	3	chlorinated	chlorinate	VERB
admet-2684	243	4	1	1	NUM
admet-2684	243	5	-	-	PUNCT
admet-2684	243	6	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	243	7	-	-	PUNCT
admet-2684	243	8	carboxanilides	carboxanilide	NOUN
admet-2684	243	9	were	be	AUX
admet-2684	243	10	synthesized	synthesize	VERB
admet-2684	243	11	by	by	ADP
admet-2684	243	12	microwave	microwave	NOUN
admet-2684	243	13	synthesis	synthesis	NOUN
admet-2684	243	14	and	and	CCONJ
admet-2684	243	15	tested	test	VERB
admet-2684	243	16	for	for	ADP
admet-2684	243	17	their	their	PRON
admet-2684	243	18	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	243	19	activity	activity	NOUN
admet-2684	243	20	against	against	ADP
admet-2684	243	21	reference	reference	NOUN
admet-2684	243	22	s.	s.	PROPN
admet-2684	243	23	aureus	aureus	PROPN
admet-2684	243	24	atcc	atcc	PROPN
admet-2684	243	25	29213	29213	NUM
admet-2684	243	26	and	and	CCONJ
admet-2684	243	27	three	three	NUM
admet-2684	243	28	clinical	clinical	ADJ
admet-2684	243	29	mrsa	mrsa	NOUN
admet-2684	243	30	isolates	isolate	NOUN
admet-2684	243	31	carrying	carry	VERB
admet-2684	243	32	the	the	DET
admet-2684	243	33	meca	meca	NOUN
admet-2684	243	34	gene	gene	NOUN
admet-2684	243	35	.	.	PUNCT
admet-2684	244	1	only	only	ADV
admet-2684	244	2	one	one	NUM
admet-2684	244	3	compound	compound	NOUN
admet-2684	244	4	,	,	PUNCT
admet-2684	244	5	n-(3,5	n-(3,5	NOUN
admet-2684	244	6	-	-	PUNCT
admet-2684	244	7	dichlorophenyl)-1	dichlorophenyl)-1	PROPN
admet-2684	244	8	-	-	PUNCT
admet-2684	244	9	hydroxynaphthalene2	hydroxynaphthalene2	NOUN
admet-2684	244	10	-	-	PUNCT
admet-2684	244	11	carboxamide	carboxamide	NOUN
admet-2684	244	12	(	(	PUNCT
admet-2684	244	13	10	10	NUM
admet-2684	244	14	)	)	PUNCT
admet-2684	244	15	,	,	PUNCT
admet-2684	244	16	was	be	AUX
admet-2684	244	17	significantly	significantly	ADV
admet-2684	244	18	active	active	ADJ
admet-2684	244	19	against	against	ADP
admet-2684	244	20	all	all	DET
admet-2684	244	21	staphylococcus	staphylococcus	NOUN
admet-2684	244	22	sp	sp	NOUN
admet-2684	244	23	.	.	PUNCT
admet-2684	245	1	the	the	DET
admet-2684	245	2	mics	mic	NOUN
admet-2684	245	3	were	be	AUX
admet-2684	245	4	the	the	DET
admet-2684	245	5	same	same	ADJ
admet-2684	245	6	against	against	ADP
admet-2684	245	7	all	all	DET
admet-2684	245	8	strains	strain	NOUN
admet-2684	245	9	(	(	PUNCT
admet-2684	245	10	0.37	0.37	NUM
admet-2684	245	11	μm	μm	NUM
admet-2684	245	12	)	)	PUNCT
admet-2684	245	13	.	.	PUNCT
admet-2684	246	1	from	from	ADP
admet-2684	246	2	the	the	DET
admet-2684	246	3	set	set	NOUN
admet-2684	246	4	of	of	ADP
admet-2684	246	5	tested	test	VERB
admet-2684	246	6	mono-	mono-	NUM
admet-2684	246	7	,	,	PUNCT
admet-2684	246	8	diand	diand	NOUN
admet-2684	246	9	trisubstituted	trisubstitute	VERB
admet-2684	246	10	derivatives	derivative	NOUN
admet-2684	246	11	,	,	PUNCT
admet-2684	246	12	it	it	PRON
admet-2684	246	13	is	be	AUX
admet-2684	246	14	evident	evident	ADJ
admet-2684	246	15	that	that	SCONJ
admet-2684	246	16	the	the	DET
admet-2684	246	17	position	position	NOUN
admet-2684	246	18	of	of	ADP
admet-2684	246	19	the	the	DET
admet-2684	246	20	chlorine	chlorine	NOUN
admet-2684	246	21	atoms	atom	NOUN
admet-2684	246	22	is	be	AUX
admet-2684	246	23	crucial	crucial	ADJ
admet-2684	246	24	for	for	ADP
admet-2684	246	25	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	246	26	activity	activity	NOUN
admet-2684	246	27	.	.	PUNCT
admet-2684	247	1	this	this	DET
admet-2684	247	2	compound	compound	NOUN
admet-2684	247	3	showed	show	VERB
admet-2684	247	4	no	no	DET
admet-2684	247	5	lethal	lethal	ADJ
admet-2684	247	6	activity	activity	NOUN
admet-2684	247	7	(	(	PUNCT
admet-2684	247	8	lc50	lc50	PROPN
admet-2684	247	9	)	)	PUNCT
admet-2684	247	10	against	against	ADP
admet-2684	247	11	the	the	DET
admet-2684	247	12	human	human	ADJ
admet-2684	247	13	monocytic	monocytic	ADJ
admet-2684	247	14	leukemia	leukemia	NOUN
admet-2684	247	15	cell	cell	NOUN
admet-2684	247	16	line	line	NOUN
admet-2684	247	17	(	(	PUNCT
admet-2684	247	18	thp-1	thp-1	ADP
admet-2684	247	19	)	)	PUNCT
admet-2684	247	20	up	up	ADP
admet-2684	247	21	to	to	ADP
admet-2684	247	22	a	a	DET
admet-2684	247	23	concentration	concentration	NOUN
admet-2684	247	24	of	of	ADP
admet-2684	247	25	30	30	NUM
admet-2684	247	26	μm	μm	NOUN
admet-2684	247	27	.	.	PUNCT
admet-2684	248	1	compound	compound	NOUN
admet-2684	248	2	10	10	NUM
admet-2684	248	3	showed	show	VERB
admet-2684	248	4	96	96	NUM
admet-2684	248	5	%	%	NOUN
admet-2684	248	6	inhibition	inhibition	NOUN
admet-2684	248	7	of	of	ADP
admet-2684	248	8	s.	s.	PROPN
admet-2684	248	9	aureus	aureus	PROPN
admet-2684	248	10	respiration	respiration	NOUN
admet-2684	248	11	at	at	ADP
admet-2684	248	12	a	a	DET
admet-2684	248	13	concentration	concentration	NOUN
admet-2684	248	14	of	of	ADP
admet-2684	248	15	16×	16×	NUM
admet-2684	248	16	mic	mic	NOUN
admet-2684	248	17	.	.	PUNCT
admet-2684	249	1	thus	thus	ADV
admet-2684	249	2	,	,	PUNCT
admet-2684	249	3	it	it	PRON
admet-2684	249	4	has	have	VERB
admet-2684	249	5	a	a	DET
admet-2684	249	6	significant	significant	ADJ
admet-2684	249	7	effect	effect	NOUN
admet-2684	249	8	,	,	PUNCT
admet-2684	249	9	but	but	CCONJ
admet-2684	249	10	at	at	ADP
admet-2684	249	11	high	high	ADJ
admet-2684	249	12	concentrations	concentration	NOUN
admet-2684	249	13	,	,	PUNCT
admet-2684	249	14	suggesting	suggest	VERB
admet-2684	249	15	that	that	DET
admet-2684	249	16	interference	interference	NOUN
admet-2684	249	17	with	with	ADP
admet-2684	249	18	energy	energy	NOUN
admet-2684	249	19	metabolism	metabolism	NOUN
admet-2684	249	20	is	be	AUX
admet-2684	249	21	not	not	PART
admet-2684	249	22	the	the	DET
admet-2684	249	23	primary	primary	ADJ
admet-2684	249	24	mechanism	mechanism	NOUN
admet-2684	249	25	of	of	ADP
admet-2684	249	26	action	action	NOUN
admet-2684	249	27	.	.	PUNCT
admet-2684	250	1	proteomic	proteomic	ADJ
admet-2684	250	2	analysis	analysis	NOUN
admet-2684	250	3	performed	perform	VERB
admet-2684	250	4	with	with	ADP
admet-2684	250	5	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	250	6	effective	effective	ADJ
admet-2684	250	7	agent	agent	NOUN
admet-2684	250	8	10	10	NUM
admet-2684	250	9	and	and	CCONJ
admet-2684	250	10	inactive	inactive	ADJ
admet-2684	250	11	isomer	isomer	NOUN
admet-2684	250	12	9	9	NUM
admet-2684	250	13	revealed	reveal	VERB
admet-2684	250	14	that	that	SCONJ
admet-2684	250	15	inactive	inactive	ADJ
admet-2684	250	16	derivative	derivative	ADJ
admet-2684	250	17	9	9	NUM
admet-2684	250	18	alters	alter	VERB
admet-2684	250	19	the	the	DET
admet-2684	250	20	proteome	proteome	NOUN
admet-2684	250	21	of	of	ADP
admet-2684	250	22	staphylococci	staphylococci	PROPN
admet-2684	250	23	more	more	ADV
admet-2684	250	24	significantly	significantly	ADV
admet-2684	250	25	than	than	ADP
admet-2684	250	26	active	active	ADJ
admet-2684	250	27	compound	compound	NOUN
admet-2684	250	28	10	10	NUM
admet-2684	250	29	.	.	PUNCT
admet-2684	251	1	the	the	DET
admet-2684	251	2	effect	effect	NOUN
admet-2684	251	3	of	of	ADP
admet-2684	251	4	agent	agent	NOUN
admet-2684	251	5	10	10	NUM
admet-2684	251	6	on	on	ADP
admet-2684	251	7	s.	s.	PROPN
admet-2684	251	8	aureus	aureus	PROPN
admet-2684	251	9	resulted	result	VERB
admet-2684	251	10	in	in	ADP
admet-2684	251	11	the	the	DET
admet-2684	251	12	downregulation	downregulation	NOUN
admet-2684	251	13	of	of	ADP
admet-2684	251	14	four	four	NUM
admet-2684	251	15	proteins	protein	NOUN
admet-2684	251	16	:	:	PUNCT
admet-2684	251	17	probable	probable	ADJ
admet-2684	251	18	tautomerase	tautomerase	NOUN
admet-2684	251	19	sav1363	sav1363	NOUN
admet-2684	251	20	,	,	PUNCT
admet-2684	251	21	ribonuclease	ribonuclease	NOUN
admet-2684	251	22	j2	j2	PROPN
admet-2684	251	23	,	,	PUNCT
admet-2684	251	24	adenylosuccinate	adenylosuccinate	ADJ
admet-2684	251	25	synthetase	synthetase	NOUN
admet-2684	251	26	,	,	PUNCT
admet-2684	251	27	and	and	CCONJ
admet-2684	251	28	especially	especially	ADV
admet-2684	251	29	atpdependent	atpdependent	ADJ
admet-2684	251	30	protease	protease	NOUN
admet-2684	251	31	atpase	atpase	PROPN
admet-2684	251	32	subunit	subunit	NOUN
admet-2684	251	33	hslu	hslu	PROPN
admet-2684	251	34	,	,	PUNCT
admet-2684	251	35	involved	involve	VERB
admet-2684	251	36	in	in	ADP
admet-2684	251	37	essential	essential	ADJ
admet-2684	251	38	processes	process	NOUN
admet-2684	251	39	for	for	ADP
admet-2684	251	40	bacterial	bacterial	ADJ
admet-2684	251	41	survival	survival	NOUN
admet-2684	251	42	and	and	CCONJ
admet-2684	251	43	growth	growth	NOUN
admet-2684	251	44	,	,	PUNCT
admet-2684	251	45	such	such	ADJ
admet-2684	251	46	as	as	ADP
admet-2684	251	47	syntheses	synthesis	NOUN
admet-2684	251	48	of	of	ADP
admet-2684	251	49	proteins	protein	NOUN
admet-2684	251	50	,	,	PUNCT
admet-2684	251	51	nucleotides	nucleotide	NOUN
admet-2684	251	52	/	/	SYM
admet-2684	251	53	nucleic	nucleic	ADJ
admet-2684	251	54	acids	acid	NOUN
admet-2684	251	55	,	,	PUNCT
admet-2684	251	56	and	and	CCONJ
admet-2684	251	57	efficient	efficient	ADJ
admet-2684	251	58	protein	protein	NOUN
admet-2684	251	59	repair	repair	NOUN
admet-2684	251	60	/	/	SYM
admet-2684	251	61	degradation	degradation	NOUN
admet-2684	251	62	.	.	PUNCT
admet-2684	252	1	it	it	PRON
admet-2684	252	2	can	can	AUX
admet-2684	252	3	be	be	AUX
admet-2684	252	4	assumed	assume	VERB
admet-2684	252	5	that	that	SCONJ
admet-2684	252	6	this	this	DET
admet-2684	252	7	downregulation	downregulation	NOUN
admet-2684	252	8	probably	probably	ADV
admet-2684	252	9	contributes	contribute	VERB
admet-2684	252	10	to	to	ADP
admet-2684	252	11	the	the	DET
admet-2684	252	12	antibacterial	antibacterial	ADJ
admet-2684	252	13	effect	effect	NOUN
admet-2684	252	14	.	.	PUNCT
admet-2684	253	1	the	the	DET
admet-2684	253	2	effect	effect	NOUN
admet-2684	253	3	of	of	ADP
admet-2684	253	4	compound	compound	NOUN
admet-2684	253	5	10	10	NUM
admet-2684	253	6	on	on	ADP
admet-2684	253	7	the	the	DET
admet-2684	253	8	proteome	proteome	NOUN
admet-2684	253	9	in	in	ADP
admet-2684	253	10	a	a	DET
admet-2684	253	11	clinical	clinical	ADJ
admet-2684	253	12	mrsa	mrsa	NOUN
admet-2684	253	13	isolate	isolate	NOUN
admet-2684	253	14	remains	remain	VERB
admet-2684	253	15	unclear	unclear	ADJ
admet-2684	253	16	despite	despite	SCONJ
admet-2684	253	17	several	several	ADJ
admet-2684	253	18	different	different	ADJ
admet-2684	253	19	experiments	experiment	NOUN
admet-2684	253	20	/	/	SYM
admet-2684	253	21	measurements	measurement	NOUN
admet-2684	253	22	and	and	CCONJ
admet-2684	253	23	will	will	AUX
admet-2684	253	24	require	require	VERB
admet-2684	253	25	further	further	ADJ
admet-2684	253	26	investigation	investigation	NOUN
admet-2684	253	27	.	.	PUNCT
admet-2684	254	1	acknowledgements	acknowledgement	NOUN
admet-2684	254	2	:	:	PUNCT
admet-2684	254	3	this	this	DET
admet-2684	254	4	work	work	NOUN
admet-2684	254	5	was	be	AUX
admet-2684	254	6	supported	support	VERB
admet-2684	254	7	by	by	ADP
admet-2684	254	8	the	the	DET
admet-2684	254	9	slovak	slovak	ADJ
admet-2684	254	10	research	research	NOUN
admet-2684	254	11	and	and	CCONJ
admet-2684	254	12	development	development	NOUN
admet-2684	254	13	agency	agency	PROPN
admet-2684	254	14	(	(	PUNCT
admet-2684	254	15	projects	project	NOUN
admet-2684	254	16	apvv-22	apvv-22	NOUN
admet-2684	254	17	-	-	PUNCT
admet-2684	254	18	0133	0133	NUM
admet-2684	254	19	,	,	PUNCT
admet-2684	254	20	apvv-21	apvv-21	PROPN
admet-2684	254	21	-	-	PUNCT
admet-2684	254	22	0321	0321	NUM
admet-2684	254	23	)	)	PUNCT
admet-2684	254	24	and	and	CCONJ
admet-2684	254	25	by	by	ADP
admet-2684	254	26	international	international	ADJ
admet-2684	254	27	centre	centre	NOUN
admet-2684	254	28	for	for	ADP
admet-2684	254	29	genetic	genetic	ADJ
admet-2684	254	30	engineering	engineering	NOUN
admet-2684	254	31	and	and	CCONJ
admet-2684	254	32	biotechnology	biotechnology	NOUN
admet-2684	254	33	(	(	PUNCT
admet-2684	254	34	project	project	NOUN
admet-2684	254	35	crp/24/017	crp/24/017	NOUN
admet-2684	254	36	)	)	PUNCT
admet-2684	254	37	.	.	PUNCT
admet-2684	255	1	special	special	ADJ
admet-2684	255	2	thanks	thank	NOUN
admet-2684	255	3	to	to	ADP
admet-2684	255	4	milos	milos	PROPN
admet-2684	255	5	makovsky	makovsky	PROPN
admet-2684	255	6	(	(	PUNCT
admet-2684	255	7	department	department	NOUN
admet-2684	255	8	of	of	ADP
admet-2684	255	9	art	art	NOUN
admet-2684	255	10	and	and	CCONJ
admet-2684	255	11	education	education	NOUN
admet-2684	255	12	,	,	PUNCT
admet-2684	255	13	faculty	faculty	NOUN
admet-2684	255	14	of	of	ADP
admet-2684	255	15	education	education	NOUN
admet-2684	255	16	,	,	PUNCT
admet-2684	255	17	j.	j.	PROPN
admet-2684	255	18	e.	e.	PROPN
admet-2684	255	19	purkyne	purkyne	PROPN
admet-2684	255	20	university	university	PROPN
admet-2684	255	21	in	in	ADP
admet-2684	255	22	usti	usti	PROPN
admet-2684	255	23	nad	nad	PROPN
admet-2684	255	24	labem	labem	PROPN
admet-2684	255	25	,	,	PUNCT
admet-2684	255	26	czech	czech	PROPN
admet-2684	255	27	republic	republic	NOUN
admet-2684	255	28	)	)	PUNCT
admet-2684	255	29	,	,	PUNCT
admet-2684	255	30	the	the	DET
admet-2684	255	31	author	author	NOUN
admet-2684	255	32	of	of	ADP
admet-2684	255	33	the	the	DET
admet-2684	255	34	illustrations	illustration	NOUN
admet-2684	255	35	in	in	ADP
admet-2684	255	36	the	the	DET
admet-2684	255	37	graphic	graphic	ADJ
admet-2684	255	38	abstract	abstract	NOUN
admet-2684	255	39	.	.	PUNCT
admet-2684	256	1	conflict	conflict	NOUN
admet-2684	256	2	of	of	ADP
admet-2684	256	3	interest	interest	NOUN
admet-2684	256	4	:	:	PUNCT
admet-2684	256	5	the	the	DET
admet-2684	256	6	authors	author	NOUN
admet-2684	256	7	declare	declare	VERB
admet-2684	256	8	no	no	DET
admet-2684	256	9	conflicts	conflict	NOUN
admet-2684	256	10	of	of	ADP
admet-2684	256	11	interest	interest	NOUN
admet-2684	256	12	.	.	PUNCT
admet-2684	257	1	references	reference	NOUN
admet-2684	257	2	[	[	X
admet-2684	257	3	1	1	X
admet-2684	257	4	]	]	PUNCT
admet-2684	257	5	who	who	PRON
admet-2684	257	6	bacterial	bacterial	ADJ
admet-2684	257	7	priority	priority	NOUN
admet-2684	257	8	pathogens	pathogen	NOUN
admet-2684	257	9	list	list	NOUN
admet-2684	257	10	,	,	PUNCT
admet-2684	257	11	2024	2024	NUM
admet-2684	257	12	.	.	PUNCT
admet-2684	258	1	https://www.who.int/news-room/factsheets/detail/antimicrobial-resistance	https://www.who.int/news-room/factsheets/detail/antimicrobial-resistance	NOUN
admet-2684	258	2	(	(	PUNCT
admet-2684	258	3	accessed	access	VERB
admet-2684	258	4	on	on	ADP
admet-2684	258	5	10	10	NUM
admet-2684	258	6	february	february	NOUN
admet-2684	258	7	2025	2025	NUM
admet-2684	258	8	)	)	PUNCT
admet-2684	258	9	.	.	PUNCT
admet-2684	259	1	[	[	X
admet-2684	259	2	2	2	X
admet-2684	259	3	]	]	PUNCT
admet-2684	259	4	who	who	PRON
admet-2684	259	5	global	global	ADJ
admet-2684	259	6	antimicrobial	antimicrobial	ADJ
admet-2684	259	7	resistance	resistance	NOUN
admet-2684	259	8	and	and	CCONJ
admet-2684	259	9	use	use	VERB
admet-2684	259	10	surveillance	surveillance	NOUN
admet-2684	259	11	system	system	NOUN
admet-2684	259	12	(	(	PUNCT
admet-2684	259	13	glass	glass	NOUN
admet-2684	259	14	)	)	PUNCT
admet-2684	259	15	report	report	NOUN
admet-2684	259	16	:	:	PUNCT
admet-2684	259	17	2022	2022	NUM
admet-2684	259	18	.	.	PUNCT
admet-2684	259	19	https://www.who.int/publications/i/item/9789240062702	https://www.who.int/publications/i/item/9789240062702	PROPN
admet-2684	259	20	(	(	PUNCT
admet-2684	259	21	accessed	access	VERB
admet-2684	259	22	on	on	ADP
admet-2684	259	23	10	10	NUM
admet-2684	259	24	february	february	NOUN
admet-2684	259	25	2025	2025	NUM
admet-2684	259	26	)	)	PUNCT
admet-2684	259	27	.	.	PUNCT
admet-2684	260	1	[	[	X
admet-2684	260	2	3	3	X
admet-2684	260	3	]	]	PUNCT
admet-2684	260	4	assessing	assess	VERB
admet-2684	260	5	the	the	DET
admet-2684	260	6	health	health	NOUN
admet-2684	260	7	burden	burden	NOUN
admet-2684	260	8	of	of	ADP
admet-2684	260	9	infections	infection	NOUN
admet-2684	260	10	with	with	ADP
admet-2684	260	11	antibiotic	antibiotic	ADJ
admet-2684	260	12	-	-	PUNCT
admet-2684	260	13	resistant	resistant	ADJ
admet-2684	260	14	bacteria	bacteria	NOUN
admet-2684	260	15	in	in	ADP
admet-2684	260	16	the	the	DET
admet-2684	260	17	eu	eu	PROPN
admet-2684	260	18	/	/	SYM
admet-2684	260	19	eea	eea	PROPN
admet-2684	260	20	,	,	PUNCT
admet-2684	260	21	2016	2016	NUM
admet-2684	260	22	-	-	SYM
admet-2684	260	23	2020	2020	NUM
admet-2684	260	24	.	.	PUNCT
admet-2684	261	1	european	european	ADJ
admet-2684	261	2	centre	centre	PROPN
admet-2684	261	3	for	for	ADP
admet-2684	261	4	disease	disease	NOUN
admet-2684	261	5	prevention	prevention	NOUN
admet-2684	261	6	and	and	CCONJ
admet-2684	261	7	control	control	NOUN
admet-2684	261	8	(	(	PUNCT
admet-2684	261	9	ecdc	ecdc	PROPN
admet-2684	261	10	):	):	PUNCT
admet-2684	261	11	stockholm	stockholm	PROPN
admet-2684	261	12	,	,	PUNCT
admet-2684	261	13	sweden	sweden	PROPN
admet-2684	261	14	,	,	PUNCT
admet-2684	261	15	2022	2022	NUM
admet-2684	261	16	.	.	PUNCT
admet-2684	262	1	https://www.ecdc.europa.eu/en/publications-data/health-burden-infections-antibiotic-resistantbacteria-2016-2020	https://www.ecdc.europa.eu/en/publications-data/health-burden-infections-antibiotic-resistantbacteria-2016-2020	PROPN
admet-2684	262	2	(	(	PUNCT
admet-2684	262	3	accessed	access	VERB
admet-2684	262	4	on	on	ADP
admet-2684	262	5	10	10	NUM
admet-2684	262	6	february	february	NOUN
admet-2684	262	7	2025	2025	NUM
admet-2684	262	8	)	)	PUNCT
admet-2684	262	9	.	.	PUNCT
admet-2684	263	1	[	[	X
admet-2684	263	2	4	4	X
admet-2684	263	3	]	]	X
admet-2684	263	4	h.	h.	PROPN
admet-2684	263	5	fongang	fongang	PROPN
admet-2684	263	6	,	,	PUNCT
admet-2684	263	7	a.t	a.t	PROPN
admet-2684	263	8	.	.	PROPN
admet-2684	263	9	mbaveng	mbaveng	PROPN
admet-2684	263	10	,	,	PUNCT
admet-2684	263	11	v.	v.	ADP
admet-2684	263	12	kuete	kuete	ADJ
admet-2684	263	13	.	.	PUNCT
admet-2684	264	1	global	global	ADJ
admet-2684	264	2	burden	burden	NOUN
admet-2684	264	3	of	of	ADP
admet-2684	264	4	bacterial	bacterial	ADJ
admet-2684	264	5	infections	infection	NOUN
admet-2684	264	6	and	and	CCONJ
admet-2684	264	7	drug	drug	NOUN
admet-2684	264	8	resistance	resistance	NOUN
admet-2684	264	9	.	.	PUNCT
admet-2684	265	1	in	in	ADP
admet-2684	265	2	advances	advance	NOUN
admet-2684	265	3	in	in	ADP
admet-2684	265	4	botanical	botanical	ADJ
admet-2684	265	5	research	research	NOUN
admet-2684	265	6	,	,	PUNCT
admet-2684	265	7	v.	v.	ADP
admet-2684	265	8	kuete	kuete	ADJ
admet-2684	265	9	(	(	PUNCT
admet-2684	265	10	ed	ed	NOUN
admet-2684	265	11	.	.	PUNCT
admet-2684	265	12	)	)	PUNCT
admet-2684	265	13	,	,	PUNCT
admet-2684	265	14	academic	academic	ADJ
admet-2684	265	15	press	press	PROPN
admet-2684	265	16	&	&	CCONJ
admet-2684	265	17	elsevier	elsevier	PROPN
admet-2684	265	18	,	,	PUNCT
admet-2684	265	19	amsterdam	amsterdam	PROPN
admet-2684	265	20	,	,	PUNCT
admet-2684	265	21	netherlands	netherlands	PROPN
admet-2684	265	22	,	,	PUNCT
admet-2684	265	23	2023	2023	NUM
admet-2684	265	24	,	,	PUNCT
admet-2684	265	25	pp.1	pp.1	NOUN
admet-2684	265	26	-	-	PUNCT
admet-2684	265	27	20	20	NUM
admet-2684	265	28	.	.	PUNCT
admet-2684	266	1	https://doi.org/10.1016/bs.abr.2022.08.001	https://doi.org/10.1016/bs.abr.2022.08.001	X
admet-2684	267	1	[	[	X
admet-2684	267	2	5	5	NUM
admet-2684	267	3	]	]	X
admet-2684	267	4	national	national	ADJ
admet-2684	267	5	academies	academy	NOUN
admet-2684	267	6	of	of	ADP
admet-2684	267	7	sciences	science	NOUN
admet-2684	267	8	,	,	PUNCT
admet-2684	267	9	engineering	engineering	NOUN
admet-2684	267	10	,	,	PUNCT
admet-2684	267	11	and	and	CCONJ
admet-2684	267	12	medicine	medicine	NOUN
admet-2684	267	13	;	;	PUNCT
admet-2684	267	14	health	health	NOUN
admet-2684	267	15	and	and	CCONJ
admet-2684	267	16	medicine	medicine	NOUN
admet-2684	267	17	division	division	NOUN
admet-2684	267	18	;	;	PUNCT
admet-2684	267	19	board	board	NOUN
admet-2684	267	20	on	on	ADP
admet-2684	267	21	population	population	NOUN
admet-2684	267	22	health	health	NOUN
admet-2684	267	23	and	and	CCONJ
admet-2684	267	24	public	public	ADJ
admet-2684	267	25	health	health	NOUN
admet-2684	267	26	practice	practice	NOUN
admet-2684	267	27	;	;	PUNCT
admet-2684	267	28	committee	committee	NOUN
admet-2684	267	29	on	on	ADP
admet-2684	267	30	the	the	DET
admet-2684	267	31	long	long	ADJ
admet-2684	267	32	-	-	PUNCT
admet-2684	267	33	term	term	NOUN
admet-2684	267	34	health	health	NOUN
admet-2684	267	35	and	and	CCONJ
admet-2684	267	36	economic	economic	ADJ
admet-2684	267	37	effects	effect	NOUN
admet-2684	267	38	of	of	ADP
admet-2684	267	39	antimicrobial	antimicrobial	ADJ
admet-2684	267	40	resistance	resistance	NOUN
admet-2684	267	41	in	in	ADP
admet-2684	267	42	the	the	DET
admet-2684	267	43	united	united	PROPN
admet-2684	267	44	states	states	PROPN
admet-2684	267	45	.	.	PUNCT
admet-2684	268	1	in	in	ADP
admet-2684	268	2	combating	combat	VERB
admet-2684	268	3	antimicrobial	antimicrobial	ADJ
admet-2684	268	4	resistance	resistance	NOUN
admet-2684	268	5	and	and	CCONJ
admet-2684	268	6	protecting	protect	VERB
admet-2684	268	7	the	the	DET
admet-2684	268	8	miracle	miracle	NOUN
admet-2684	268	9	of	of	ADP
admet-2684	268	10	modern	modern	ADJ
admet-2684	268	11	medicine	medicine	NOUN
admet-2684	268	12	,	,	PUNCT
admet-2684	268	13	g.h	g.h	PROPN
admet-2684	268	14	.	.	PROPN
admet-2684	268	15	palmer	palmer	PROPN
admet-2684	268	16	,	,	PUNCT
admet-2684	268	17	g.j	g.j	PROPN
admet-2684	268	18	.	.	PROPN
admet-2684	268	19	buckley	buckley	PROPN
admet-2684	268	20	(	(	PUNCT
admet-2684	268	21	eds	eds	PROPN
admet-2684	268	22	.	.	PUNCT
admet-2684	268	23	)	)	PUNCT
admet-2684	268	24	,	,	PUNCT
admet-2684	268	25	national	national	PROPN
admet-2684	268	26	academies	academies	PROPN
admet-2684	268	27	press	press	PROPN
admet-2684	268	28	,	,	PUNCT
admet-2684	268	29	washington	washington	PROPN
admet-2684	268	30	d.c	d.c	PROPN
admet-2684	268	31	.	.	PROPN
admet-2684	268	32	,	,	PUNCT
admet-2684	268	33	usa	usa	PROPN
admet-2684	268	34	,	,	PUNCT
admet-2684	268	35	2022	2022	NUM
admet-2684	268	36	.	.	PUNCT
admet-2684	269	1	https://nap.nationalacademies.org/catalog/26350/combatinghttps://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance	https://nap.nationalacademies.org/catalog/26350/combatinghttps://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance	PROPN
admet-2684	269	2	https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance	https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance	PROPN
admet-2684	269	3	https://www.who.int/publications/i/item/9789240062702	https://www.who.int/publications/i/item/9789240062702	PROPN
admet-2684	269	4	https://www.ecdc.europa.eu/en/publications-data/health-burden-infections-antibiotic-resistant-bacteria-2016-2020	https://www.ecdc.europa.eu/en/publications-data/health-burden-infections-antibiotic-resistant-bacteria-2016-2020	NOUN
admet-2684	269	5	https://www.ecdc.europa.eu/en/publications-data/health-burden-infections-antibiotic-resistant-bacteria-2016-2020	https://www.ecdc.europa.eu/en/publications-data/health-burden-infections-antibiotic-resistant-bacteria-2016-2020	NOUN
admet-2684	269	6	https://doi.org/10.1016/bs.abr.2022.08.001	https://doi.org/10.1016/bs.abr.2022.08.001	PROPN
admet-2684	269	7	https://nap.nationalacademies.org/catalog/26350/combating-antimicrobial-resistance-and-protecting-the-miracle-of-modern-medicine	https://nap.nationalacademies.org/catalog/26350/combating-antimicrobial-resistance-and-protecting-the-miracle-of-modern-medicine	PROPN
admet-2684	269	8	admet	admet	PROPN
admet-2684	269	9	&	&	CCONJ
admet-2684	269	10	dmpk	dmpk	PROPN
admet-2684	269	11	13(2	13(2	PROPN
admet-2684	269	12	)	)	PUNCT
admet-2684	269	13	(	(	PUNCT
admet-2684	269	14	2025	2025	NUM
admet-2684	269	15	)	)	PUNCT
admet-2684	269	16	2684	2684	NUM
admet-2684	269	17	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	269	18	effect	effect	NOUN
admet-2684	269	19	of	of	ADP
admet-2684	269	20	chlorinated	chlorinate	VERB
admet-2684	269	21	1	1	NUM
admet-2684	269	22	-	-	PUNCT
admet-2684	269	23	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	269	24	-	-	PUNCT
admet-2684	269	25	carboxanilides	carboxanilide	NOUN
admet-2684	269	26	doi	doi	NOUN
admet-2684	269	27	:	:	PUNCT
admet-2684	269	28	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	269	29	13	13	NUM
admet-2684	269	30	antimicrobial	antimicrobial	ADJ
admet-2684	269	31	-	-	PUNCT
admet-2684	269	32	resistance	resistance	NOUN
admet-2684	269	33	-	-	PUNCT
admet-2684	269	34	and	and	CCONJ
admet-2684	269	35	-	-	PUNCT
admet-2684	269	36	protecting	protect	VERB
admet-2684	269	37	-	-	PUNCT
admet-2684	269	38	the	the	DET
admet-2684	269	39	-	-	PUNCT
admet-2684	269	40	miracle	miracle	NOUN
admet-2684	269	41	-	-	PUNCT
admet-2684	269	42	of	of	ADP
admet-2684	269	43	-	-	PUNCT
admet-2684	269	44	modern	modern	ADJ
admet-2684	269	45	-	-	PUNCT
admet-2684	269	46	medicine	medicine	NOUN
admet-2684	269	47	(	(	PUNCT
admet-2684	269	48	accessed	access	VERB
admet-2684	269	49	on	on	ADP
admet-2684	269	50	10	10	NUM
admet-2684	269	51	february	february	NOUN
admet-2684	269	52	2025	2025	NUM
admet-2684	269	53	)	)	PUNCT
admet-2684	269	54	.	.	PUNCT
admet-2684	270	1	[	[	X
admet-2684	270	2	6	6	NUM
admet-2684	270	3	]	]	SYM
admet-2684	270	4	gbd	gbd	NOUN
admet-2684	270	5	2021	2021	NUM
admet-2684	270	6	antimicrobial	antimicrobial	ADJ
admet-2684	270	7	resistance	resistance	NOUN
admet-2684	270	8	collaborators	collaborator	NOUN
admet-2684	270	9	.	.	PUNCT
admet-2684	271	1	global	global	ADJ
admet-2684	271	2	burden	burden	NOUN
admet-2684	271	3	of	of	ADP
admet-2684	271	4	bacterial	bacterial	ADJ
admet-2684	271	5	antimicrobial	antimicrobial	ADJ
admet-2684	271	6	resistance	resistance	NOUN
admet-2684	271	7	1990	1990	NUM
admet-2684	271	8	-	-	SYM
admet-2684	271	9	2021	2021	NUM
admet-2684	271	10	:	:	PUNCT
admet-2684	271	11	a	a	DET
admet-2684	271	12	systematic	systematic	ADJ
admet-2684	271	13	analysis	analysis	NOUN
admet-2684	271	14	with	with	ADP
admet-2684	271	15	forecasts	forecast	NOUN
admet-2684	271	16	to	to	ADP
admet-2684	271	17	2050	2050	NUM
admet-2684	271	18	.	.	PUNCT
admet-2684	272	1	lancet	lancet	NOUN
admet-2684	272	2	404	404	NUM
admet-2684	272	3	(	(	PUNCT
admet-2684	272	4	2024	2024	NUM
admet-2684	272	5	)	)	PUNCT
admet-2684	272	6	1199	1199	NUM
admet-2684	272	7	-	-	SYM
admet-2684	272	8	1226	1226	NUM
admet-2684	272	9	.	.	PUNCT
admet-2684	273	1	https://doi.org/10.1016/s0140-6736(24)01867-1	https://doi.org/10.1016/s0140-6736(24)01867-1	VERB
admet-2684	274	1	[	[	X
admet-2684	274	2	7	7	NUM
admet-2684	274	3	]	]	SYM
admet-2684	274	4	gbd	gbd	NOUN
admet-2684	274	5	2019	2019	NUM
admet-2684	274	6	antimicrobial	antimicrobial	ADJ
admet-2684	274	7	resistance	resistance	NOUN
admet-2684	274	8	collaborators	collaborator	NOUN
admet-2684	274	9	.	.	PUNCT
admet-2684	275	1	global	global	ADJ
admet-2684	275	2	mortality	mortality	NOUN
admet-2684	275	3	associated	associate	VERB
admet-2684	275	4	with	with	ADP
admet-2684	275	5	33	33	NUM
admet-2684	275	6	bacterial	bacterial	ADJ
admet-2684	275	7	pathogens	pathogen	NOUN
admet-2684	275	8	in	in	ADP
admet-2684	275	9	2019	2019	NUM
admet-2684	275	10	:	:	PUNCT
admet-2684	275	11	a	a	DET
admet-2684	275	12	systematic	systematic	ADJ
admet-2684	275	13	analysis	analysis	NOUN
admet-2684	275	14	for	for	ADP
admet-2684	275	15	the	the	DET
admet-2684	275	16	global	global	ADJ
admet-2684	275	17	burden	burden	NOUN
admet-2684	275	18	of	of	ADP
admet-2684	275	19	disease	disease	NOUN
admet-2684	275	20	study	study	NOUN
admet-2684	275	21	2019	2019	NUM
admet-2684	275	22	.	.	PUNCT
admet-2684	276	1	lancet	lancet	NOUN
admet-2684	276	2	400	400	NUM
admet-2684	276	3	(	(	PUNCT
admet-2684	276	4	2022	2022	NUM
admet-2684	276	5	)	)	PUNCT
admet-2684	276	6	2221	2221	NUM
admet-2684	276	7	-	-	SYM
admet-2684	276	8	2248	2248	NUM
admet-2684	276	9	.	.	PUNCT
admet-2684	277	1	https://doi.org/10.1016/s0140-6736(22)02185-7	https://doi.org/10.1016/s0140-6736(22)02185-7	X
admet-2684	278	1	[	[	X
admet-2684	278	2	8	8	X
admet-2684	278	3	]	]	PUNCT
admet-2684	278	4	j.	j.	PROPN
admet-2684	278	5	jampilek	jampilek	PROPN
admet-2684	278	6	.	.	PUNCT
admet-2684	279	1	design	design	NOUN
admet-2684	279	2	and	and	CCONJ
admet-2684	279	3	discovery	discovery	NOUN
admet-2684	279	4	of	of	ADP
admet-2684	279	5	new	new	ADJ
admet-2684	279	6	antibacterial	antibacterial	ADJ
admet-2684	279	7	agents	agent	NOUN
admet-2684	279	8	:	:	PUNCT
admet-2684	279	9	advances	advance	NOUN
admet-2684	279	10	,	,	PUNCT
admet-2684	279	11	perspectives	perspective	NOUN
admet-2684	279	12	,	,	PUNCT
admet-2684	279	13	challenges	challenge	NOUN
admet-2684	279	14	.	.	PUNCT
admet-2684	280	1	current	current	ADJ
admet-2684	280	2	medicinal	medicinal	ADJ
admet-2684	280	3	chemistry	chemistry	NOUN
admet-2684	280	4	25	25	NUM
admet-2684	280	5	(	(	PUNCT
admet-2684	280	6	2018	2018	NUM
admet-2684	280	7	)	)	PUNCT
admet-2684	280	8	4972	4972	NUM
admet-2684	280	9	-	-	SYM
admet-2684	280	10	5006	5006	NUM
admet-2684	280	11	.	.	PUNCT
admet-2684	280	12	https://doi.org/10.2174/0929867324666170918122633	https://doi.org/10.2174/0929867324666170918122633	NOUN
admet-2684	281	1	[	[	X
admet-2684	281	2	9	9	NUM
admet-2684	281	3	]	]	PUNCT
admet-2684	281	4	m.	m.	NOUN
admet-2684	281	5	miethke	miethke	PROPN
admet-2684	281	6	,	,	PUNCT
admet-2684	281	7	m.	m.	NOUN
admet-2684	281	8	pieroni	pieroni	PROPN
admet-2684	281	9	,	,	PUNCT
admet-2684	281	10	t.	t.	PROPN
admet-2684	281	11	weber	weber	PROPN
admet-2684	281	12	,	,	PUNCT
admet-2684	281	13	m.	m.	NOUN
admet-2684	281	14	brönstrup	brönstrup	PROPN
admet-2684	281	15	,	,	PUNCT
admet-2684	281	16	p.	p.	PROPN
admet-2684	281	17	hammann	hammann	PROPN
admet-2684	281	18	,	,	PUNCT
admet-2684	281	19	l.	l.	PROPN
admet-2684	281	20	halby	halby	PROPN
admet-2684	281	21	,	,	PUNCT
admet-2684	281	22	p.b	p.b	PROPN
admet-2684	281	23	.	.	PROPN
admet-2684	281	24	arimondo	arimondo	NOUN
admet-2684	281	25	,	,	PUNCT
admet-2684	281	26	p.	p.	PROPN
admet-2684	281	27	glaser	glaser	PROPN
admet-2684	281	28	,	,	PUNCT
admet-2684	281	29	b.	b.	PROPN
admet-2684	281	30	aigle	aigle	PROPN
admet-2684	281	31	,	,	PUNCT
admet-2684	281	32	h.b	h.b	PROPN
admet-2684	281	33	.	.	PROPN
admet-2684	281	34	bode	bode	PROPN
admet-2684	281	35	,	,	PUNCT
admet-2684	281	36	r.	r.	PROPN
admet-2684	281	37	moreira	moreira	PROPN
admet-2684	281	38	,	,	PUNCT
admet-2684	281	39	y.	y.	PROPN
admet-2684	281	40	li	li	PROPN
admet-2684	281	41	,	,	PUNCT
admet-2684	281	42	a.	a.	PROPN
admet-2684	281	43	luzhetskyy	luzhetskyy	PROPN
admet-2684	281	44	,	,	PUNCT
admet-2684	281	45	m.h	m.h	PROPN
admet-2684	281	46	.	.	PROPN
admet-2684	281	47	medema	medema	PROPN
admet-2684	281	48	,	,	PUNCT
admet-2684	281	49	j.l	j.l	PROPN
admet-2684	281	50	.	.	PROPN
admet-2684	281	51	pernodet	pernodet	PROPN
admet-2684	281	52	,	,	PUNCT
admet-2684	281	53	m.	m.	NOUN
admet-2684	281	54	stadler	stadler	NOUN
admet-2684	281	55	,	,	PUNCT
admet-2684	281	56	j.r	j.r	PROPN
admet-2684	281	57	.	.	PROPN
admet-2684	281	58	tormo	tormo	PROPN
admet-2684	281	59	,	,	PUNCT
admet-2684	281	60	o.	o.	PROPN
admet-2684	281	61	genilloud	genilloud	PROPN
admet-2684	281	62	,	,	PUNCT
admet-2684	281	63	a.w	a.w	PROPN
admet-2684	281	64	.	.	PROPN
admet-2684	281	65	truman	truman	PROPN
admet-2684	281	66	,	,	PUNCT
admet-2684	281	67	k.j	k.j	PROPN
admet-2684	281	68	.	.	PROPN
admet-2684	281	69	weissman	weissman	PROPN
admet-2684	281	70	,	,	PUNCT
admet-2684	281	71	e.	e.	PROPN
admet-2684	281	72	takano	takano	PROPN
admet-2684	281	73	,	,	PUNCT
admet-2684	281	74	s.	s.	PROPN
admet-2684	281	75	sabatini	sabatini	PROPN
admet-2684	281	76	,	,	PUNCT
admet-2684	281	77	e.	e.	PROPN
admet-2684	281	78	stegmann	stegmann	PROPN
admet-2684	281	79	,	,	PUNCT
admet-2684	281	80	h.	h.	PROPN
admet-2684	281	81	brötz	brötz	ADV
admet-2684	281	82	-	-	PUNCT
admet-2684	281	83	oesterhelt	oesterhelt	PROPN
admet-2684	281	84	,	,	PUNCT
admet-2684	281	85	w.	w.	PROPN
admet-2684	281	86	wohlleben	wohlleben	PROPN
admet-2684	281	87	,	,	PUNCT
admet-2684	281	88	m.	m.	NOUN
admet-2684	281	89	seemann	seemann	PROPN
admet-2684	281	90	,	,	PUNCT
admet-2684	281	91	m.	m.	NOUN
admet-2684	281	92	empting	empting	PROPN
admet-2684	281	93	,	,	PUNCT
admet-2684	281	94	a.k.h	a.k.h	PROPN
admet-2684	281	95	.	.	PROPN
admet-2684	281	96	hirsch	hirsch	PROPN
admet-2684	281	97	,	,	PUNCT
admet-2684	281	98	b.	b.	PROPN
admet-2684	281	99	loretz	loretz	PROPN
admet-2684	281	100	,	,	PUNCT
admet-2684	281	101	c.m	c.m	PROPN
admet-2684	281	102	.	.	PROPN
admet-2684	281	103	lehr	lehr	PROPN
admet-2684	281	104	,	,	PUNCT
admet-2684	281	105	a.	a.	NOUN
admet-2684	281	106	titz	titz	PROPN
admet-2684	281	107	,	,	PUNCT
admet-2684	281	108	j.	j.	PROPN
admet-2684	281	109	herrmann	herrmann	PROPN
admet-2684	281	110	,	,	PUNCT
admet-2684	281	111	t.	t.	NOUN
admet-2684	281	112	jaeger	jaeger	PROPN
admet-2684	281	113	,	,	PUNCT
admet-2684	281	114	s.	s.	PROPN
admet-2684	281	115	alt	alt	PROPN
admet-2684	281	116	,	,	PUNCT
admet-2684	281	117	t.	t.	PROPN
admet-2684	281	118	hesterkamp	hesterkamp	PROPN
admet-2684	281	119	,	,	PUNCT
admet-2684	281	120	m.	m.	NOUN
admet-2684	281	121	winterhalter	winterhalter	PROPN
admet-2684	281	122	,	,	PUNCT
admet-2684	281	123	a.	a.	NOUN
admet-2684	281	124	schiefer	schiefer	NOUN
admet-2684	281	125	,	,	PUNCT
admet-2684	281	126	k.	k.	PROPN
admet-2684	281	127	pfarr	pfarr	PROPN
admet-2684	281	128	,	,	PUNCT
admet-2684	281	129	a.	a.	PROPN
admet-2684	281	130	hoerauf	hoerauf	PROPN
admet-2684	281	131	,	,	PUNCT
admet-2684	281	132	h.	h.	PROPN
admet-2684	281	133	graz	graz	PROPN
admet-2684	281	134	,	,	PUNCT
admet-2684	281	135	m.	m.	PROPN
admet-2684	281	136	graz	graz	PROPN
admet-2684	281	137	,	,	PUNCT
admet-2684	281	138	m.	m.	NOUN
admet-2684	281	139	lindvall	lindvall	PROPN
admet-2684	281	140	,	,	PUNCT
admet-2684	281	141	s.	s.	PROPN
admet-2684	281	142	ramurthy	ramurthy	PROPN
admet-2684	281	143	,	,	PUNCT
admet-2684	281	144	a.	a.	NOUN
admet-2684	281	145	karlén	karlén	PROPN
admet-2684	281	146	,	,	PUNCT
admet-2684	281	147	m.	m.	NOUN
admet-2684	281	148	van	van	PROPN
admet-2684	281	149	dongen	dongen	PROPN
admet-2684	281	150	,	,	PUNCT
admet-2684	281	151	h.	h.	PROPN
admet-2684	281	152	petkovic	petkovic	PROPN
admet-2684	281	153	,	,	PUNCT
admet-2684	281	154	a.	a.	PROPN
admet-2684	281	155	keller	keller	PROPN
admet-2684	281	156	,	,	PUNCT
admet-2684	281	157	f.	f.	PROPN
admet-2684	281	158	peyrane	peyrane	PROPN
admet-2684	281	159	,	,	PUNCT
admet-2684	281	160	s.	s.	PROPN
admet-2684	281	161	donadio	donadio	PROPN
admet-2684	281	162	,	,	PUNCT
admet-2684	281	163	l.	l.	PROPN
admet-2684	281	164	fraisse	fraisse	PROPN
admet-2684	281	165	,	,	PUNCT
admet-2684	281	166	l.j.v	l.j.v	PROPN
admet-2684	281	167	.	.	PUNCT
admet-2684	281	168	piddock	piddock	PROPN
admet-2684	281	169	,	,	PUNCT
admet-2684	281	170	i.h	i.h	PROPN
admet-2684	281	171	.	.	PROPN
admet-2684	281	172	gilbert	gilbert	PROPN
admet-2684	281	173	,	,	PUNCT
admet-2684	281	174	h.e	h.e	PROPN
admet-2684	281	175	.	.	PROPN
admet-2684	281	176	moser	moser	PROPN
admet-2684	281	177	,	,	PUNCT
admet-2684	281	178	r.	r.	PROPN
admet-2684	281	179	müller	müller	PROPN
admet-2684	281	180	.	.	PUNCT
admet-2684	282	1	towards	towards	ADP
admet-2684	282	2	the	the	DET
admet-2684	282	3	sustainable	sustainable	ADJ
admet-2684	282	4	discovery	discovery	NOUN
admet-2684	282	5	and	and	CCONJ
admet-2684	282	6	development	development	NOUN
admet-2684	282	7	of	of	ADP
admet-2684	282	8	new	new	ADJ
admet-2684	282	9	antibiotics	antibiotic	NOUN
admet-2684	282	10	.	.	PUNCT
admet-2684	283	1	nature	nature	NOUN
admet-2684	283	2	reviews	review	VERB
admet-2684	283	3	chemistry	chemistry	NOUN
admet-2684	283	4	5	5	NUM
admet-2684	283	5	(	(	PUNCT
admet-2684	283	6	2021	2021	NUM
admet-2684	283	7	)	)	PUNCT
admet-2684	283	8	726	726	NUM
admet-2684	283	9	-	-	SYM
admet-2684	283	10	749	749	NUM
admet-2684	283	11	.	.	PUNCT
admet-2684	283	12	https://doi.org/10.1038/s41570-021-00313-1	https://doi.org/10.1038/s41570-021-00313-1	NOUN
admet-2684	284	1	[	[	X
admet-2684	284	2	10	10	NUM
admet-2684	284	3	]	]	X
admet-2684	284	4	n.j	n.j	PROPN
admet-2684	284	5	.	.	PROPN
admet-2684	284	6	ayon	ayon	PROPN
admet-2684	284	7	.	.	PUNCT
admet-2684	285	1	high	high	ADJ
admet-2684	285	2	-	-	PUNCT
admet-2684	285	3	throughput	throughput	NOUN
admet-2684	285	4	screening	screening	NOUN
admet-2684	285	5	of	of	ADP
admet-2684	285	6	natural	natural	ADJ
admet-2684	285	7	product	product	NOUN
admet-2684	285	8	and	and	CCONJ
admet-2684	285	9	synthetic	synthetic	ADJ
admet-2684	285	10	molecule	molecule	NOUN
admet-2684	285	11	libraries	library	NOUN
admet-2684	285	12	for	for	ADP
admet-2684	285	13	antibacterial	antibacterial	ADJ
admet-2684	285	14	drug	drug	NOUN
admet-2684	285	15	discovery	discovery	NOUN
admet-2684	285	16	.	.	PUNCT
admet-2684	286	1	metabolites	metabolite	NOUN
admet-2684	286	2	13	13	NUM
admet-2684	286	3	(	(	PUNCT
admet-2684	286	4	2023	2023	NUM
admet-2684	286	5	)	)	PUNCT
admet-2684	286	6	625	625	NUM
admet-2684	286	7	.	.	PUNCT
admet-2684	287	1	https://doi.org/10.3390/metabo13050625	https://doi.org/10.3390/metabo13050625	NOUN
admet-2684	288	1	[	[	X
admet-2684	288	2	11	11	NUM
admet-2684	288	3	]	]	X
admet-2684	288	4	n.k	n.k	PROPN
admet-2684	288	5	.	.	PROPN
admet-2684	288	6	boyd	boyd	PROPN
admet-2684	288	7	,	,	PUNCT
admet-2684	288	8	c.	c.	PROPN
admet-2684	288	9	teng	teng	PROPN
admet-2684	288	10	,	,	PUNCT
admet-2684	288	11	c.r	c.r	PROPN
admet-2684	288	12	.	.	PROPN
admet-2684	288	13	frei	frei	PROPN
admet-2684	288	14	.	.	PUNCT
admet-2684	289	1	brief	brief	ADJ
admet-2684	289	2	overview	overview	NOUN
admet-2684	289	3	of	of	ADP
admet-2684	289	4	approaches	approach	NOUN
admet-2684	289	5	and	and	CCONJ
admet-2684	289	6	challenges	challenge	NOUN
admet-2684	289	7	in	in	ADP
admet-2684	289	8	new	new	ADJ
admet-2684	289	9	antibiotic	antibiotic	ADJ
admet-2684	289	10	development	development	NOUN
admet-2684	289	11	:	:	PUNCT
admet-2684	289	12	a	a	DET
admet-2684	289	13	focus	focus	NOUN
admet-2684	289	14	on	on	ADP
admet-2684	289	15	drug	drug	NOUN
admet-2684	289	16	repurposing	repurposing	NOUN
admet-2684	289	17	.	.	PUNCT
admet-2684	290	1	frontiers	frontier	NOUN
admet-2684	290	2	in	in	ADP
admet-2684	290	3	cellular	cellular	ADJ
admet-2684	290	4	and	and	CCONJ
admet-2684	290	5	infection	infection	NOUN
admet-2684	290	6	microbiology	microbiology	NOUN
admet-2684	290	7	11	11	NUM
admet-2684	290	8	(	(	PUNCT
admet-2684	290	9	2021	2021	NUM
admet-2684	290	10	)	)	PUNCT
admet-2684	290	11	684515	684515	NUM
admet-2684	290	12	.	.	PUNCT
admet-2684	291	1	https://doi.org/10.3389/fcimb.2021.684515	https://doi.org/10.3389/fcimb.2021.684515	PROPN
admet-2684	291	2	[	[	X
admet-2684	291	3	12	12	NUM
admet-2684	291	4	]	]	X
admet-2684	291	5	s.k	s.k	PROPN
admet-2684	291	6	.	.	PUNCT
admet-2684	291	7	mondal	mondal	PROPN
admet-2684	291	8	,	,	PUNCT
admet-2684	291	9	s.	s.	PROPN
admet-2684	291	10	chakraborty	chakraborty	PROPN
admet-2684	291	11	,	,	PUNCT
admet-2684	291	12	s.	s.	PROPN
admet-2684	291	13	manna	manna	PROPN
admet-2684	291	14	,	,	PUNCT
admet-2684	291	15	s.m	s.m	PROPN
admet-2684	291	16	.	.	PROPN
admet-2684	291	17	mandal	mandal	PROPN
admet-2684	291	18	.	.	PUNCT
admet-2684	292	1	antimicrobial	antimicrobial	ADJ
admet-2684	292	2	nanoparticles	nanoparticle	NOUN
admet-2684	292	3	:	:	PUNCT
admet-2684	292	4	current	current	ADJ
admet-2684	292	5	landscape	landscape	NOUN
admet-2684	292	6	and	and	CCONJ
admet-2684	292	7	future	future	ADJ
admet-2684	292	8	challenges	challenge	NOUN
admet-2684	292	9	.	.	PUNCT
admet-2684	293	1	rsc	rsc	PROPN
admet-2684	293	2	pharmaceutics	pharmaceutic	NOUN
admet-2684	293	3	1	1	NUM
admet-2684	293	4	(	(	PUNCT
admet-2684	293	5	2024	2024	NUM
admet-2684	293	6	)	)	PUNCT
admet-2684	293	7	388	388	NUM
admet-2684	293	8	-	-	SYM
admet-2684	293	9	402	402	NUM
admet-2684	293	10	.	.	PUNCT
admet-2684	293	11	https://doi.org/10.1039/d4pm00032c	https://doi.org/10.1039/d4pm00032c	X
admet-2684	294	1	[	[	X
admet-2684	294	2	13	13	NUM
admet-2684	294	3	]	]	X
admet-2684	294	4	d.a	d.a	PROPN
admet-2684	294	5	.	.	PROPN
admet-2684	294	6	gray	gray	PROPN
admet-2684	294	7	,	,	PUNCT
admet-2684	294	8	m.	m.	NOUN
admet-2684	294	9	wenzel	wenzel	PROPN
admet-2684	294	10	.	.	PUNCT
admet-2684	295	1	multitarget	multitarget	PROPN
admet-2684	295	2	approaches	approach	NOUN
admet-2684	295	3	against	against	ADP
admet-2684	295	4	multiresistant	multiresistant	ADJ
admet-2684	295	5	superbugs	superbug	NOUN
admet-2684	295	6	.	.	PUNCT
admet-2684	296	1	acs	acs	PROPN
admet-2684	296	2	infectious	infectious	ADJ
admet-2684	296	3	diseases	disease	NOUN
admet-2684	296	4	6	6	NUM
admet-2684	296	5	(	(	PUNCT
admet-2684	296	6	2020	2020	NUM
admet-2684	296	7	)	)	PUNCT
admet-2684	296	8	1346	1346	NUM
admet-2684	296	9	-	-	SYM
admet-2684	296	10	1365	1365	NUM
admet-2684	296	11	.	.	PUNCT
admet-2684	297	1	https://doi.org/10.1021/acsinfecdis.0c00001	https://doi.org/10.1021/acsinfecdis.0c00001	ADJ
admet-2684	298	1	[	[	X
admet-2684	298	2	14	14	NUM
admet-2684	298	3	]	]	X
admet-2684	298	4	c.j	c.j	PROPN
admet-2684	298	5	.	.	PROPN
admet-2684	298	6	suckling	suckling	PROPN
admet-2684	298	7	,	,	PUNCT
admet-2684	298	8	i.s	i.s	PROPN
admet-2684	298	9	.	.	PROPN
admet-2684	298	10	hunter	hunter	PROPN
admet-2684	298	11	,	,	PUNCT
admet-2684	298	12	f.j	f.j	PROPN
admet-2684	298	13	.	.	PROPN
admet-2684	298	14	scott	scott	PROPN
admet-2684	298	15	.	.	PROPN
admet-2684	298	16	multitargeted	multitargete	VERB
admet-2684	298	17	anti	anti	ADJ
admet-2684	298	18	-	-	ADJ
admet-2684	298	19	infective	infective	ADJ
admet-2684	298	20	drugs	drug	NOUN
admet-2684	298	21	:	:	PUNCT
admet-2684	298	22	resilience	resilience	NOUN
admet-2684	298	23	to	to	ADP
admet-2684	298	24	resistance	resistance	NOUN
admet-2684	298	25	in	in	ADP
admet-2684	298	26	the	the	DET
admet-2684	298	27	antimicrobial	antimicrobial	ADJ
admet-2684	298	28	resistance	resistance	NOUN
admet-2684	298	29	era	era	NOUN
admet-2684	298	30	.	.	PUNCT
admet-2684	299	1	future	future	ADJ
admet-2684	299	2	drug	drug	NOUN
admet-2684	299	3	discovery	discovery	NOUN
admet-2684	299	4	4	4	NUM
admet-2684	299	5	(	(	PUNCT
admet-2684	299	6	2022	2022	NUM
admet-2684	299	7	)	)	PUNCT
admet-2684	299	8	fdd73	fdd73	NOUN
admet-2684	299	9	.	.	PUNCT
admet-2684	299	10	https://doi.org/10.4155/fdd2022-0001	https://doi.org/10.4155/fdd2022-0001	PROPN
admet-2684	300	1	[	[	X
admet-2684	300	2	15	15	NUM
admet-2684	300	3	]	]	X
admet-2684	300	4	j.	j.	PROPN
admet-2684	300	5	feng	feng	PROPN
admet-2684	300	6	,	,	PUNCT
admet-2684	300	7	y.	y.	PROPN
admet-2684	300	8	zheng	zheng	PROPN
admet-2684	300	9	,	,	PUNCT
admet-2684	300	10	w.	w.	PROPN
admet-2684	300	11	ma	ma	PROPN
admet-2684	300	12	,	,	PUNCT
admet-2684	300	13	a.	a.	PROPN
admet-2684	300	14	ihsan	ihsan	PROPN
admet-2684	300	15	,	,	PUNCT
admet-2684	300	16	h.	h.	PROPN
admet-2684	300	17	hao	hao	PROPN
admet-2684	300	18	,	,	PUNCT
admet-2684	300	19	g.	g.	PROPN
admet-2684	300	20	cheng	cheng	PROPN
admet-2684	300	21	,	,	PUNCT
admet-2684	300	22	x.	x.	PROPN
admet-2684	300	23	wang	wang	PROPN
admet-2684	300	24	.	.	PUNCT
admet-2684	301	1	multitarget	multitarget	PROPN
admet-2684	301	2	antibacterial	antibacterial	ADJ
admet-2684	301	3	drugs	drug	NOUN
admet-2684	301	4	:	:	PUNCT
admet-2684	301	5	an	an	DET
admet-2684	301	6	effective	effective	ADJ
admet-2684	301	7	strategy	strategy	NOUN
admet-2684	301	8	to	to	PART
admet-2684	301	9	combat	combat	VERB
admet-2684	301	10	bacterial	bacterial	ADJ
admet-2684	301	11	resistance	resistance	NOUN
admet-2684	301	12	.	.	PUNCT
admet-2684	302	1	pharmacology	pharmacology	NOUN
admet-2684	302	2	&	&	CCONJ
admet-2684	302	3	therapeutics	therapeutic	NOUN
admet-2684	302	4	252	252	NUM
admet-2684	302	5	(	(	PUNCT
admet-2684	302	6	2023	2023	NUM
admet-2684	302	7	)	)	PUNCT
admet-2684	302	8	108550	108550	NUM
admet-2684	302	9	.	.	PUNCT
admet-2684	303	1	https://doi.org/10.1016/j.pharmthera.2023.108550	https://doi.org/10.1016/j.pharmthera.2023.108550	PROPN
admet-2684	304	1	[	[	X
admet-2684	304	2	16	16	NUM
admet-2684	304	3	]	]	X
admet-2684	304	4	j.b	j.b	PROPN
admet-2684	304	5	.	.	PUNCT
admet-2684	304	6	bremner	bremner	PROPN
admet-2684	304	7	.	.	PUNCT
admet-2684	305	1	an	an	DET
admet-2684	305	2	update	update	NOUN
admet-2684	305	3	review	review	NOUN
admet-2684	305	4	of	of	ADP
admet-2684	305	5	approaches	approach	NOUN
admet-2684	305	6	to	to	ADP
admet-2684	305	7	multiple	multiple	ADJ
admet-2684	305	8	action	action	NOUN
admet-2684	305	9	-	-	PUNCT
admet-2684	305	10	based	base	VERB
admet-2684	305	11	antibacterials	antibacterial	NOUN
admet-2684	305	12	.	.	PUNCT
admet-2684	306	1	antibiotics	antibiotic	NOUN
admet-2684	306	2	12	12	NUM
admet-2684	306	3	(	(	PUNCT
admet-2684	306	4	2023	2023	NUM
admet-2684	306	5	)	)	PUNCT
admet-2684	306	6	865	865	NUM
admet-2684	306	7	.	.	PUNCT
admet-2684	306	8	https://doi.org/10.3390/antibiotics12050865	https://doi.org/10.3390/antibiotics12050865	VERB
admet-2684	306	9	[	[	X
admet-2684	306	10	17	17	NUM
admet-2684	306	11	]	]	X
admet-2684	306	12	g.	g.	PROPN
admet-2684	306	13	stelitano	stelitano	PROPN
admet-2684	306	14	,	,	PUNCT
admet-2684	306	15	j.c	j.c	PROPN
admet-2684	306	16	.	.	PROPN
admet-2684	306	17	sammartino	sammartino	PROPN
admet-2684	306	18	,	,	PUNCT
admet-2684	306	19	l.r	l.r	PROPN
admet-2684	306	20	.	.	PROPN
admet-2684	306	21	chiarelli	chiarelli	PROPN
admet-2684	306	22	.	.	PUNCT
admet-2684	307	1	multitargeting	multitargete	VERB
admet-2684	307	2	compounds	compound	VERB
admet-2684	307	3	:	:	PUNCT
admet-2684	307	4	a	a	DET
admet-2684	307	5	promising	promising	ADJ
admet-2684	307	6	strategy	strategy	NOUN
admet-2684	307	7	to	to	PART
admet-2684	307	8	overcome	overcome	VERB
admet-2684	307	9	multi	multi	ADJ
admet-2684	307	10	-	-	ADJ
admet-2684	307	11	drug	drug	ADJ
admet-2684	307	12	resistant	resistant	ADJ
admet-2684	307	13	tuberculosis	tuberculosis	NOUN
admet-2684	307	14	.	.	PUNCT
admet-2684	308	1	molecules	molecule	NOUN
admet-2684	308	2	25	25	NUM
admet-2684	308	3	(	(	PUNCT
admet-2684	308	4	2020	2020	NUM
admet-2684	308	5	)	)	PUNCT
admet-2684	308	6	1239	1239	NUM
admet-2684	308	7	.	.	PUNCT
admet-2684	309	1	https://doi.org/10.3390/molecules25051239	https://doi.org/10.3390/molecules25051239	PROPN
admet-2684	309	2	[	[	X
admet-2684	309	3	18	18	NUM
admet-2684	309	4	]	]	PUNCT
admet-2684	309	5	m.	m.	NOUN
admet-2684	309	6	lagadinou	lagadinou	NOUN
admet-2684	309	7	,	,	PUNCT
admet-2684	309	8	m.o	m.o	PROPN
admet-2684	309	9	.	.	PROPN
admet-2684	309	10	onisor	onisor	PROPN
admet-2684	309	11	,	,	PUNCT
admet-2684	309	12	a.	a.	NOUN
admet-2684	309	13	rigas	rigas	PROPN
admet-2684	309	14	,	,	PUNCT
admet-2684	309	15	d.v	d.v	PROPN
admet-2684	309	16	.	.	PROPN
admet-2684	309	17	musetescu	musetescu	PROPN
admet-2684	309	18	,	,	PUNCT
admet-2684	309	19	d.	d.	PROPN
admet-2684	309	20	gkentzi	gkentzi	PROPN
admet-2684	309	21	,	,	PUNCT
admet-2684	309	22	s.f	s.f	PROPN
admet-2684	309	23	.	.	PROPN
admet-2684	309	24	assimakopoulos	assimakopoulos	PROPN
admet-2684	309	25	,	,	PUNCT
admet-2684	309	26	g.	g.	PROPN
admet-2684	309	27	panos	panos	PROPN
admet-2684	309	28	,	,	PUNCT
admet-2684	309	29	m.	m.	NOUN
admet-2684	309	30	marangos	marango	NOUN
admet-2684	309	31	.	.	PUNCT
admet-2684	310	1	antimicrobial	antimicrobial	ADJ
admet-2684	310	2	properties	property	NOUN
admet-2684	310	3	on	on	ADP
admet-2684	310	4	non	non	ADJ
admet-2684	310	5	-	-	ADJ
admet-2684	310	6	antibiotic	antibiotic	ADJ
admet-2684	310	7	drugs	drug	NOUN
admet-2684	310	8	in	in	ADP
admet-2684	310	9	the	the	DET
admet-2684	310	10	era	era	NOUN
admet-2684	310	11	of	of	ADP
admet-2684	310	12	increased	increase	VERB
admet-2684	310	13	bacterial	bacterial	ADJ
admet-2684	310	14	resistance	resistance	NOUN
admet-2684	310	15	.	.	PUNCT
admet-2684	311	1	antibiotics	antibiotic	NOUN
admet-2684	311	2	9	9	NUM
admet-2684	311	3	(	(	PUNCT
admet-2684	311	4	2020	2020	NUM
admet-2684	311	5	)	)	PUNCT
admet-2684	311	6	107	107	NUM
admet-2684	311	7	.	.	PUNCT
admet-2684	312	1	https://doi.org/10.3390/antibiotics9030107	https://doi.org/10.3390/antibiotics9030107	PROPN
admet-2684	312	2	[	[	X
admet-2684	312	3	19	19	NUM
admet-2684	312	4	]	]	PUNCT
admet-2684	312	5	a.	a.	NOUN
admet-2684	312	6	imramovsky	imramovsky	NOUN
admet-2684	312	7	,	,	PUNCT
admet-2684	312	8	m.	m.	NOUN
admet-2684	312	9	pesko	pesko	ADV
admet-2684	312	10	,	,	PUNCT
admet-2684	312	11	k.	k.	PROPN
admet-2684	312	12	kralova	kralova	PROPN
admet-2684	312	13	,	,	PUNCT
admet-2684	312	14	m.	m.	PROPN
admet-2684	312	15	vejsova	vejsova	PROPN
admet-2684	312	16	,	,	PUNCT
admet-2684	312	17	j.	j.	PROPN
admet-2684	312	18	stolarikova	stolarikova	PROPN
admet-2684	312	19	,	,	PUNCT
admet-2684	312	20	j.	j.	PROPN
admet-2684	312	21	vinsova	vinsova	PROPN
admet-2684	312	22	,	,	PUNCT
admet-2684	312	23	j.	j.	PROPN
admet-2684	312	24	jampilek	jampilek	PROPN
admet-2684	312	25	.	.	PUNCT
admet-2684	313	1	investigating	investigate	VERB
admet-2684	313	2	spectrum	spectrum	NOUN
admet-2684	313	3	of	of	ADP
admet-2684	313	4	biological	biological	ADJ
admet-2684	313	5	activity	activity	NOUN
admet-2684	313	6	of	of	ADP
admet-2684	313	7	4and	4and	NOUN
admet-2684	313	8	5	5	NUM
admet-2684	313	9	-	-	PUNCT
admet-2684	313	10	chloro-2	chloro-2	VERB
admet-2684	313	11	-	-	PUNCT
admet-2684	313	12	hydroxy	hydroxy	VERB
admet-2684	313	13	-	-	PUNCT
admet-2684	313	14	n-[2-(arylamino)-1	n-[2-(arylamino)-1	NOUN
admet-2684	313	15	-	-	PUNCT
admet-2684	313	16	alkyl-2oxoethyl]benzamides	alkyl-2oxoethyl]benzamides	PROPN
admet-2684	313	17	.	.	PUNCT
admet-2684	313	18	molecules	molecule	NOUN
admet-2684	313	19	16	16	NUM
admet-2684	313	20	(	(	PUNCT
admet-2684	313	21	2011	2011	NUM
admet-2684	313	22	)	)	PUNCT
admet-2684	313	23	2414	2414	NUM
admet-2684	313	24	-	-	SYM
admet-2684	313	25	2430	2430	NUM
admet-2684	313	26	.	.	PUNCT
admet-2684	314	1	https://doi.org/10.3390/molecules16032414	https://doi.org/10.3390/molecules16032414	PRON
admet-2684	315	1	[	[	X
admet-2684	315	2	20	20	NUM
admet-2684	315	3	]	]	PUNCT
admet-2684	315	4	i.	i.	NOUN
admet-2684	315	5	kushkevych	kushkevych	PROPN
admet-2684	315	6	,	,	PUNCT
admet-2684	315	7	p.	p.	NOUN
admet-2684	315	8	kollar	kollar	PROPN
admet-2684	315	9	,	,	PUNCT
admet-2684	315	10	a.l	a.l	PROPN
admet-2684	315	11	.	.	PROPN
admet-2684	315	12	ferreira	ferreira	PROPN
admet-2684	315	13	,	,	PUNCT
admet-2684	315	14	d.	d.	PROPN
admet-2684	315	15	palma	palma	PROPN
admet-2684	315	16	,	,	PUNCT
admet-2684	315	17	a.	a.	PROPN
admet-2684	315	18	duarte	duarte	PROPN
admet-2684	315	19	,	,	PUNCT
admet-2684	315	20	m.m	m.m	PROPN
admet-2684	315	21	.	.	PROPN
admet-2684	315	22	lopes	lopes	PROPN
admet-2684	315	23	,	,	PUNCT
admet-2684	315	24	m.	m.	NOUN
admet-2684	315	25	bartos	bartos	PROPN
admet-2684	315	26	,	,	PUNCT
admet-2684	315	27	k.	k.	PROPN
admet-2684	315	28	pauk	pauk	PROPN
admet-2684	315	29	,	,	PUNCT
admet-2684	315	30	a.	a.	NOUN
admet-2684	315	31	imramovsky	imramovsky	PROPN
admet-2684	315	32	,	,	PUNCT
admet-2684	315	33	j.	j.	PROPN
admet-2684	315	34	jampilek	jampilek	PROPN
admet-2684	315	35	.	.	PUNCT
admet-2684	316	1	antimicrobial	antimicrobial	ADJ
admet-2684	316	2	effect	effect	NOUN
admet-2684	316	3	of	of	ADP
admet-2684	316	4	salicylamide	salicylamide	VERB
admet-2684	316	5	derivatives	derivative	NOUN
admet-2684	316	6	against	against	ADP
admet-2684	316	7	intestinal	intestinal	ADJ
admet-2684	316	8	sulfate	sulfate	NOUN
admet-2684	316	9	-	-	PUNCT
admet-2684	316	10	reducing	reduce	VERB
admet-2684	316	11	bacteria	bacteria	NOUN
admet-2684	316	12	.	.	PUNCT
admet-2684	317	1	journal	journal	NOUN
admet-2684	317	2	of	of	ADP
admet-2684	317	3	applied	apply	VERB
admet-2684	317	4	biomedicine	biomedicine	NOUN
admet-2684	317	5	14	14	NUM
admet-2684	317	6	(	(	PUNCT
admet-2684	317	7	2016	2016	NUM
admet-2684	317	8	)	)	PUNCT
admet-2684	317	9	125	125	NUM
admet-2684	317	10	-	-	SYM
admet-2684	317	11	130	130	NUM
admet-2684	317	12	.	.	PUNCT
admet-2684	318	1	https://doi.org/10.1016/j.jab.2016.01.005	https://doi.org/10.1016/j.jab.2016.01.005	PROPN
admet-2684	319	1	[	[	X
admet-2684	319	2	21	21	NUM
admet-2684	319	3	]	]	X
admet-2684	319	4	l.	l.	PROPN
admet-2684	319	5	borbala	borbala	PROPN
admet-2684	319	6	-	-	PUNCT
admet-2684	319	7	horvath	horvath	PROPN
admet-2684	319	8	,	,	PUNCT
admet-2684	319	9	m.	m.	NOUN
admet-2684	319	10	kratky	kratky	PROPN
admet-2684	319	11	,	,	PUNCT
admet-2684	319	12	v.	v.	ADP
admet-2684	319	13	pflegr	pflegr	NOUN
admet-2684	319	14	,	,	PUNCT
admet-2684	319	15	e.	e.	PROPN
admet-2684	319	16	mahes	mahes	PROPN
admet-2684	319	17	,	,	PUNCT
admet-2684	319	18	g.	g.	PROPN
admet-2684	319	19	gyulai	gyulai	PROPN
admet-2684	319	20	,	,	PUNCT
admet-2684	319	21	g.	g.	PROPN
admet-2684	319	22	kohut	kohut	PROPN
admet-2684	319	23	,	,	PUNCT
admet-2684	319	24	a.	a.	NOUN
admet-2684	319	25	babiczky	babiczky	NOUN
admet-2684	319	26	,	,	PUNCT
admet-2684	319	27	b.	b.	PROPN
admet-2684	319	28	biri	biri	PROPN
admet-2684	319	29	-	-	PUNCT
admet-2684	319	30	kovacs	kovacs	PROPN
admet-2684	319	31	,	,	PUNCT
admet-2684	319	32	z.	z.	PROPN
admet-2684	319	33	baranyai	baranyai	PROPN
admet-2684	319	34	,	,	PUNCT
admet-2684	319	35	j.	j.	PROPN
admet-2684	319	36	vinsova	vinsova	PROPN
admet-2684	319	37	,	,	PUNCT
admet-2684	319	38	s	s	PART
admet-2684	319	39	bosze	bosze	NOUN
admet-2684	319	40	.	.	PUNCT
admet-2684	320	1	host	host	NOUN
admet-2684	320	2	cell	cell	NOUN
admet-2684	320	3	targeting	target	VERB
admet-2684	320	4	of	of	ADP
admet-2684	320	5	novel	novel	ADJ
admet-2684	320	6	antimycobacterial	antimycobacterial	ADJ
admet-2684	320	7	4	4	NUM
admet-2684	320	8	-	-	PUNCT
admet-2684	320	9	aminosalicylic	aminosalicylic	NOUN
admet-2684	320	10	acid	acid	PROPN
admet-2684	320	11	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	320	12	https://nap.nationalacademies.org/catalog/26350/combating-antimicrobial-resistance-and-protecting-the-miracle-of-modern-medicine	https://nap.nationalacademies.org/catalog/26350/combating-antimicrobial-resistance-and-protecting-the-miracle-of-modern-medicine	X
admet-2684	321	1	https://doi.org/10.1016/s0140-6736(24)01867-1	https://doi.org/10.1016/s0140-6736(24)01867-1	VERB
admet-2684	321	2	https://doi.org/10.1016/s0140-6736(22)02185-7	https://doi.org/10.1016/s0140-6736(22)02185-7	ADJ
admet-2684	321	3	https://doi.org/10.2174/0929867324666170918122633	https://doi.org/10.2174/0929867324666170918122633	NOUN
admet-2684	321	4	https://doi.org/10.1038/s41570-021-00313-1	https://doi.org/10.1038/s41570-021-00313-1	NOUN
admet-2684	321	5	https://doi.org/10.3390/metabo13050625	https://doi.org/10.3390/metabo13050625	PROPN
admet-2684	321	6	https://doi.org/10.3389/fcimb.2021.684515	https://doi.org/10.3389/fcimb.2021.684515	PROPN
admet-2684	321	7	https://doi.org/10.1039/d4pm00032c	https://doi.org/10.1039/d4pm00032c	PROPN
admet-2684	321	8	https://doi.org/10.1021/acsinfecdis.0c00001	https://doi.org/10.1021/acsinfecdis.0c00001	ADJ
admet-2684	321	9	https://doi.org/10.4155/fdd-2022-0001	https://doi.org/10.4155/fdd-2022-0001	NOUN
admet-2684	321	10	https://doi.org/10.4155/fdd-2022-0001	https://doi.org/10.4155/fdd-2022-0001	ADJ
admet-2684	321	11	https://doi.org/10.1016/j.pharmthera.2023.108550	https://doi.org/10.1016/j.pharmthera.2023.108550	PROPN
admet-2684	321	12	https://doi.org/10.3390/antibiotics12050865	https://doi.org/10.3390/antibiotics12050865	VERB
admet-2684	321	13	https://doi.org/10.3390/molecules25051239	https://doi.org/10.3390/molecules25051239	PROPN
admet-2684	321	14	https://doi.org/10.3390/antibiotics9030107	https://doi.org/10.3390/antibiotics9030107	PROPN
admet-2684	321	15	https://doi.org/10.3390/molecules16032414	https://doi.org/10.3390/molecules16032414	PROPN
admet-2684	321	16	https://doi.org/10.1016/j.jab.2016.01.005	https://doi.org/10.1016/j.jab.2016.01.005	PROPN
admet-2684	321	17	l.	l.	PROPN
admet-2684	321	18	vrablova	vrablova	PROPN
admet-2684	321	19	et	et	PROPN
admet-2684	321	20	al	al	PROPN
admet-2684	321	21	.	.	PROPN
admet-2684	321	22	admet	admet	PROPN
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admet-2684	321	24	dmpk	dmpk	PROPN
admet-2684	321	25	13(2	13(2	PROPN
admet-2684	321	26	)	)	PUNCT
admet-2684	321	27	(	(	PUNCT
admet-2684	321	28	2025	2025	NUM
admet-2684	321	29	)	)	PUNCT
admet-2684	321	30	2684	2684	NUM
admet-2684	321	31	14	14	NUM
admet-2684	321	32	derivatives	derivative	NOUN
admet-2684	321	33	with	with	ADP
admet-2684	321	34	tuftsin	tuftsin	NOUN
admet-2684	321	35	carrier	carrier	NOUN
admet-2684	321	36	peptides	peptide	NOUN
admet-2684	321	37	.	.	PUNCT
admet-2684	322	1	european	european	ADJ
admet-2684	322	2	journal	journal	PROPN
admet-2684	322	3	of	of	ADP
admet-2684	322	4	pharmaceutics	pharmaceutic	NOUN
admet-2684	322	5	and	and	CCONJ
admet-2684	322	6	biopharmaceutics	biopharmaceutic	NOUN
admet-2684	322	7	174	174	NUM
admet-2684	322	8	(	(	PUNCT
admet-2684	322	9	2022	2022	NUM
admet-2684	322	10	)	)	PUNCT
admet-2684	322	11	111	111	NUM
admet-2684	322	12	-	-	SYM
admet-2684	322	13	130	130	NUM
admet-2684	322	14	.	.	PUNCT
admet-2684	323	1	https://doi.org/10.1016/j.ejpb.2022.03.009	https://doi.org/10.1016/j.ejpb.2022.03.009	PROPN
admet-2684	324	1	[	[	X
admet-2684	324	2	22	22	NUM
admet-2684	324	3	]	]	X
admet-2684	324	4	g.	g.	PROPN
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admet-2684	324	6	,	,	PUNCT
admet-2684	324	7	s.	s.	PROPN
admet-2684	324	8	monteiro	monteiro	PROPN
admet-2684	324	9	,	,	PUNCT
admet-2684	324	10	r.	r.	PROPN
admet-2684	324	11	vosatka	vosatka	PROPN
admet-2684	324	12	,	,	PUNCT
admet-2684	324	13	m.	m.	NOUN
admet-2684	324	14	kratky	kratky	PROPN
admet-2684	324	15	,	,	PUNCT
admet-2684	324	16	l.	l.	PROPN
admet-2684	324	17	navratilova	navratilova	PROPN
admet-2684	324	18	,	,	PUNCT
admet-2684	324	19	f.	f.	PROPN
admet-2684	324	20	trejtnar	trejtnar	PROPN
admet-2684	324	21	,	,	PUNCT
admet-2684	324	22	j.	j.	PROPN
admet-2684	324	23	stolarikova	stolarikova	PROPN
admet-2684	324	24	,	,	PUNCT
admet-2684	324	25	j.	j.	PROPN
admet-2684	324	26	vinsova	vinsova	PROPN
admet-2684	324	27	.	.	PUNCT
admet-2684	325	1	novel	novel	ADJ
admet-2684	325	2	salicylanilides	salicylanilide	NOUN
admet-2684	325	3	from	from	ADP
admet-2684	325	4	4,5	4,5	NUM
admet-2684	325	5	-	-	PUNCT
admet-2684	325	6	dihalogenated	dihalogenate	VERB
admet-2684	325	7	salicylic	salicylic	ADJ
admet-2684	325	8	acids	acid	NOUN
admet-2684	325	9	:	:	PUNCT
admet-2684	325	10	synthesis	synthesis	NOUN
admet-2684	325	11	,	,	PUNCT
admet-2684	325	12	antimicrobial	antimicrobial	ADJ
admet-2684	325	13	activity	activity	NOUN
admet-2684	325	14	and	and	CCONJ
admet-2684	325	15	cytotoxicity	cytotoxicity	NOUN
admet-2684	325	16	.	.	PUNCT
admet-2684	326	1	bioorganic	bioorganic	ADJ
admet-2684	326	2	and	and	CCONJ
admet-2684	326	3	medicinal	medicinal	ADJ
admet-2684	326	4	chemistry	chemistry	NOUN
admet-2684	326	5	25	25	NUM
admet-2684	326	6	(	(	PUNCT
admet-2684	326	7	2017	2017	NUM
admet-2684	326	8	)	)	PUNCT
admet-2684	326	9	1524	1524	NUM
admet-2684	326	10	-	-	SYM
admet-2684	326	11	1532	1532	NUM
admet-2684	326	12	.	.	PUNCT
admet-2684	327	1	https://doi.org/10.1016/j.bmc.2017.01.016	https://doi.org/10.1016/j.bmc.2017.01.016	PROPN
admet-2684	328	1	[	[	X
admet-2684	328	2	23	23	NUM
admet-2684	328	3	]	]	PUNCT
admet-2684	328	4	m.	m.	NOUN
admet-2684	328	5	alhashimi	alhashimi	PROPN
admet-2684	328	6	,	,	PUNCT
admet-2684	328	7	a.	a.	PROPN
admet-2684	328	8	mayhoub	mayhoub	PROPN
admet-2684	328	9	,	,	PUNCT
admet-2684	328	10	m.n	m.n	PROPN
admet-2684	328	11	.	.	PROPN
admet-2684	328	12	seleem	seleem	PROPN
admet-2684	328	13	.	.	PUNCT
admet-2684	329	1	repurposing	repurpose	VERB
admet-2684	329	2	salicylamide	salicylamide	NOUN
admet-2684	329	3	for	for	ADP
admet-2684	329	4	combating	combat	VERB
admet-2684	329	5	multidrug	multidrug	NOUN
admet-2684	329	6	-	-	PUNCT
admet-2684	329	7	resistant	resistant	ADJ
admet-2684	329	8	neisseria	neisseria	NOUN
admet-2684	329	9	gonorrhoeae	gonorrhoeae	PROPN
admet-2684	329	10	.	.	PUNCT
admet-2684	330	1	antimicrobial	antimicrobial	ADJ
admet-2684	330	2	agents	agent	NOUN
admet-2684	330	3	and	and	CCONJ
admet-2684	330	4	chemotherapy	chemotherapy	NOUN
admet-2684	330	5	63	63	NUM
admet-2684	330	6	(	(	PUNCT
admet-2684	330	7	2019	2019	NUM
admet-2684	330	8	)	)	PUNCT
admet-2684	330	9	e01225	e01225	NOUN
admet-2684	330	10	-	-	PUNCT
admet-2684	330	11	19	19	NUM
admet-2684	330	12	.	.	PUNCT
admet-2684	331	1	https://doi.org/10.1128/aac.01225-19	https://doi.org/10.1128/aac.01225-19	PROPN
admet-2684	332	1	[	[	X
admet-2684	332	2	24	24	NUM
admet-2684	332	3	]	]	X
admet-2684	332	4	h.	h.	PROPN
admet-2684	332	5	almolhim	almolhim	PROPN
admet-2684	332	6	,	,	PUNCT
admet-2684	332	7	a.e.m	a.e.m	PROPN
admet-2684	332	8	.	.	PUNCT
admet-2684	333	1	elhassanny	elhassanny	PROPN
admet-2684	333	2	,	,	PUNCT
admet-2684	333	3	n.s	n.s	PROPN
admet-2684	333	4	.	.	PROPN
admet-2684	333	5	abutaleb	abutaleb	PROPN
admet-2684	333	6	,	,	PUNCT
admet-2684	333	7	a.s	a.s	PROPN
admet-2684	333	8	.	.	PROPN
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admet-2684	333	10	,	,	PUNCT
admet-2684	333	11	m.n	m.n	PROPN
admet-2684	333	12	.	.	PROPN
admet-2684	333	13	seleem	seleem	PROPN
admet-2684	333	14	,	,	PUNCT
admet-2684	333	15	p.r	p.r	PROPN
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admet-2684	333	18	.	.	PUNCT
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admet-2684	334	2	salicylic	salicylic	NOUN
admet-2684	334	3	acid	acid	NOUN
admet-2684	334	4	analogs	analog	NOUN
admet-2684	334	5	offer	offer	VERB
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admet-2684	334	7	potency	potency	NOUN
admet-2684	334	8	against	against	ADP
admet-2684	334	9	multidrug	multidrug	NOUN
admet-2684	334	10	-	-	PUNCT
admet-2684	334	11	resistant	resistant	ADJ
admet-2684	334	12	neisseria	neisseria	NOUN
admet-2684	334	13	gonorrhoeae	gonorrhoeae	PROPN
admet-2684	334	14	and	and	CCONJ
admet-2684	334	15	good	good	ADJ
admet-2684	334	16	selectivity	selectivity	NOUN
admet-2684	334	17	against	against	ADP
admet-2684	334	18	commensal	commensal	ADJ
admet-2684	334	19	vaginal	vaginal	ADJ
admet-2684	334	20	bacteria	bacteria	NOUN
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admet-2684	335	5	2023	2023	NUM
admet-2684	335	6	)	)	PUNCT
admet-2684	335	7	14468	14468	NUM
admet-2684	335	8	.	.	PUNCT
admet-2684	336	1	https://doi.org/10.1038/s41598-023-41442-5	https://doi.org/10.1038/s41598-023-41442-5	NOUN
admet-2684	336	2	[	[	X
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admet-2684	336	4	]	]	PUNCT
admet-2684	336	5	t.	t.	PROPN
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admet-2684	336	12	nabeshima	nabeshima	PROPN
admet-2684	336	13	,	,	PUNCT
admet-2684	336	14	y.	y.	PROPN
admet-2684	336	15	nakagawa	nakagawa	PROPN
admet-2684	336	16	,	,	PUNCT
admet-2684	336	17	t.	t.	PROPN
admet-2684	336	18	okada	okada	PROPN
admet-2684	336	19	,	,	PUNCT
admet-2684	336	20	n.	n.	PROPN
admet-2684	336	21	toyooka	toyooka	PROPN
admet-2684	336	22	,	,	PUNCT
admet-2684	336	23	k.	k.	PROPN
admet-2684	336	24	kusaka	kusaka	PROPN
admet-2684	336	25	.	.	PUNCT
admet-2684	337	1	rafoxanide	rafoxanide	PROPN
admet-2684	337	2	,	,	PUNCT
admet-2684	337	3	a	a	DET
admet-2684	337	4	salicylanilide	salicylanilide	ADJ
admet-2684	337	5	anthelmintic	anthelmintic	NOUN
admet-2684	337	6	,	,	PUNCT
admet-2684	337	7	interacts	interact	VERB
admet-2684	337	8	with	with	ADP
admet-2684	337	9	human	human	ADJ
admet-2684	337	10	plasma	plasma	NOUN
admet-2684	337	11	protein	protein	NOUN
admet-2684	337	12	transthyretin	transthyretin	PROPN
admet-2684	337	13	.	.	PUNCT
admet-2684	338	1	the	the	DET
admet-2684	338	2	febs	febs	NOUN
admet-2684	338	3	journal	journal	PROPN
admet-2684	338	4	290	290	NUM
admet-2684	338	5	(	(	PUNCT
admet-2684	338	6	2023	2023	NUM
admet-2684	338	7	)	)	PUNCT
admet-2684	338	8	5158	5158	NUM
admet-2684	338	9	-	-	SYM
admet-2684	338	10	5170	5170	NUM
admet-2684	338	11	.	.	PUNCT
admet-2684	339	1	https://doi.org/10.1111/febs.16915	https://doi.org/10.1111/febs.16915	NOUN
admet-2684	340	1	[	[	X
admet-2684	340	2	26	26	NUM
admet-2684	340	3	]	]	PUNCT
admet-2684	340	4	t.	t.	PROPN
admet-2684	340	5	kauerova	kauerova	PROPN
admet-2684	340	6	,	,	PUNCT
admet-2684	340	7	m.j	m.j	PROPN
admet-2684	340	8	.	.	PROPN
admet-2684	340	9	perez	perez	PROPN
admet-2684	340	10	-	-	PUNCT
admet-2684	340	11	perez	perez	PROPN
admet-2684	340	12	,	,	PUNCT
admet-2684	340	13	p.	p.	NOUN
admet-2684	340	14	kollar	kollar	PROPN
admet-2684	340	15	.	.	PUNCT
admet-2684	341	1	salicylanilides	salicylanilide	NOUN
admet-2684	341	2	and	and	CCONJ
admet-2684	341	3	their	their	PRON
admet-2684	341	4	anti	anti	ADJ
admet-2684	341	5	-	-	ADJ
admet-2684	341	6	cancer	cancer	ADJ
admet-2684	341	7	properties	property	NOUN
admet-2684	341	8	.	.	PUNCT
admet-2684	342	1	international	international	ADJ
admet-2684	342	2	journal	journal	NOUN
admet-2684	342	3	of	of	ADP
admet-2684	342	4	molecular	molecular	ADJ
admet-2684	342	5	sciences	science	NOUN
admet-2684	342	6	24	24	NUM
admet-2684	342	7	(	(	PUNCT
admet-2684	342	8	2023	2023	NUM
admet-2684	342	9	)	)	PUNCT
admet-2684	342	10	1728	1728	NUM
admet-2684	342	11	.	.	PUNCT
admet-2684	343	1	https://doi.org/10.3390/ijms24021728	https://doi.org/10.3390/ijms24021728	PROPN
admet-2684	344	1	[	[	X
admet-2684	344	2	27	27	NUM
admet-2684	344	3	]	]	PUNCT
admet-2684	344	4	j.	j.	PROPN
admet-2684	344	5	otevrel	otevrel	PROPN
admet-2684	344	6	,	,	PUNCT
admet-2684	344	7	z.	z.	PROPN
admet-2684	344	8	mandelova	mandelova	PROPN
admet-2684	344	9	,	,	PUNCT
admet-2684	344	10	m.	m.	NOUN
admet-2684	344	11	pesko	pesko	ADV
admet-2684	344	12	,	,	PUNCT
admet-2684	344	13	j.	j.	PROPN
admet-2684	344	14	guo	guo	PROPN
admet-2684	344	15	,	,	PUNCT
admet-2684	344	16	k.	k.	PROPN
admet-2684	344	17	kralova	kralova	PROPN
admet-2684	344	18	,	,	PUNCT
admet-2684	344	19	f.	f.	PROPN
admet-2684	344	20	sersen	sersen	PROPN
admet-2684	344	21	,	,	PUNCT
admet-2684	344	22	m.	m.	PROPN
admet-2684	344	23	vejsova	vejsova	PROPN
admet-2684	344	24	,	,	PUNCT
admet-2684	344	25	d.s	d.s	PROPN
admet-2684	344	26	.	.	PROPN
admet-2684	344	27	kalinowski	kalinowski	PROPN
admet-2684	344	28	,	,	PUNCT
admet-2684	344	29	z.	z.	PROPN
admet-2684	344	30	kovacevic	kovacevic	PROPN
admet-2684	344	31	,	,	PUNCT
admet-2684	344	32	a.	a.	NOUN
admet-2684	344	33	coffey	coffey	PROPN
admet-2684	344	34	,	,	PUNCT
admet-2684	344	35	j.	j.	PROPN
admet-2684	344	36	csollei	csollei	PROPN
admet-2684	344	37	,	,	PUNCT
admet-2684	344	38	d.r	d.r	PROPN
admet-2684	344	39	.	.	PROPN
admet-2684	344	40	richardson	richardson	PROPN
admet-2684	344	41	,	,	PUNCT
admet-2684	344	42	j.	j.	PROPN
admet-2684	344	43	jampilek	jampilek	PROPN
admet-2684	344	44	.	.	PUNCT
admet-2684	345	1	investigating	investigate	VERB
admet-2684	345	2	the	the	DET
admet-2684	345	3	spectrum	spectrum	NOUN
admet-2684	345	4	of	of	ADP
admet-2684	345	5	biological	biological	ADJ
admet-2684	345	6	activity	activity	NOUN
admet-2684	345	7	of	of	ADP
admet-2684	345	8	ring	ring	NOUN
admet-2684	345	9	-	-	PUNCT
admet-2684	345	10	substituted	substitute	VERB
admet-2684	345	11	salicylanilides	salicylanilide	NOUN
admet-2684	345	12	and	and	CCONJ
admet-2684	345	13	carbamoylphenylcarbamates	carbamoylphenylcarbamate	NOUN
admet-2684	345	14	.	.	PUNCT
admet-2684	346	1	molecules	molecule	NOUN
admet-2684	346	2	15	15	NUM
admet-2684	346	3	(	(	PUNCT
admet-2684	346	4	2010	2010	NUM
admet-2684	346	5	)	)	PUNCT
admet-2684	346	6	8122	8122	NUM
admet-2684	346	7	-	-	SYM
admet-2684	346	8	8142	8142	NUM
admet-2684	346	9	.	.	PUNCT
admet-2684	347	1	https://doi.org/10.3390/molecules15118122	https://doi.org/10.3390/molecules15118122	PROPN
admet-2684	348	1	[	[	X
admet-2684	348	2	28	28	NUM
admet-2684	348	3	]	]	X
admet-2684	348	4	a.	a.	NOUN
admet-2684	348	5	imramovsky	imramovsky	NOUN
admet-2684	348	6	,	,	PUNCT
admet-2684	348	7	m.	m.	NOUN
admet-2684	348	8	pesko	pesko	ADV
admet-2684	348	9	,	,	PUNCT
admet-2684	348	10	j.m	j.m	PROPN
admet-2684	348	11	.	.	PROPN
admet-2684	348	12	ferriz	ferriz	PROPN
admet-2684	348	13	,	,	PUNCT
admet-2684	348	14	k.	k.	PROPN
admet-2684	348	15	kralova	kralova	PROPN
admet-2684	348	16	,	,	PUNCT
admet-2684	348	17	j.	j.	PROPN
admet-2684	348	18	vinsova	vinsova	PROPN
admet-2684	348	19	,	,	PUNCT
admet-2684	348	20	j	j	PROPN
admet-2684	348	21	jampilek	jampilek	PROPN
admet-2684	348	22	.	.	PUNCT
admet-2684	349	1	photosynthesis	photosynthesis	NOUN
admet-2684	349	2	-	-	PUNCT
admet-2684	349	3	inhibiting	inhibit	VERB
admet-2684	349	4	efficiency	efficiency	NOUN
admet-2684	349	5	of	of	ADP
admet-2684	349	6	4	4	NUM
admet-2684	349	7	-	-	PUNCT
admet-2684	349	8	chloro-2-(chlorophenylcarbamoyl)phenyl	chloro-2-(chlorophenylcarbamoyl)phenyl	NOUN
admet-2684	349	9	alkylcarbamates	alkylcarbamate	NOUN
admet-2684	349	10	.	.	PUNCT
admet-2684	350	1	bioorganic	bioorganic	PROPN
admet-2684	350	2	&	&	CCONJ
admet-2684	350	3	medicinal	medicinal	ADJ
admet-2684	350	4	chemistry	chemistry	NOUN
admet-2684	350	5	letters	letter	NOUN
admet-2684	350	6	21	21	NUM
admet-2684	350	7	(	(	PUNCT
admet-2684	350	8	2011	2011	NUM
admet-2684	350	9	)	)	PUNCT
admet-2684	350	10	4564	4564	NUM
admet-2684	350	11	-	-	SYM
admet-2684	350	12	4567	4567	NUM
admet-2684	350	13	.	.	PUNCT
admet-2684	351	1	https://doi.org/10.1016/j.bmcl.2011.05.118	https://doi.org/10.1016/j.bmcl.2011.05.118	X
admet-2684	352	1	[	[	X
admet-2684	352	2	29	29	NUM
admet-2684	352	3	]	]	PUNCT
admet-2684	352	4	t.	t.	PROPN
admet-2684	352	5	gonec	gonec	PROPN
admet-2684	352	6	,	,	PUNCT
admet-2684	352	7	j.	j.	PROPN
admet-2684	352	8	kos	kos	PROPN
admet-2684	352	9	,	,	PUNCT
admet-2684	352	10	i.	i.	PROPN
admet-2684	352	11	zadrazilova	zadrazilova	PROPN
admet-2684	352	12	,	,	PUNCT
admet-2684	352	13	m.	m.	NOUN
admet-2684	352	14	pesko	pesko	ADV
admet-2684	352	15	,	,	PUNCT
admet-2684	352	16	s.	s.	PROPN
admet-2684	352	17	keltosova	keltosova	PROPN
admet-2684	352	18	,	,	PUNCT
admet-2684	352	19	j.	j.	PROPN
admet-2684	352	20	tengler	tengler	PROPN
admet-2684	352	21	,	,	PUNCT
admet-2684	352	22	p.	p.	PROPN
admet-2684	352	23	bobal	bobal	PROPN
admet-2684	352	24	,	,	PUNCT
admet-2684	352	25	p.	p.	PROPN
admet-2684	352	26	kollar	kollar	PROPN
admet-2684	352	27	,	,	PUNCT
admet-2684	352	28	a.	a.	NOUN
admet-2684	352	29	cizek	cizek	PROPN
admet-2684	352	30	,	,	PUNCT
admet-2684	352	31	k.	k.	PROPN
admet-2684	352	32	kralova	kralova	PROPN
admet-2684	352	33	,	,	PUNCT
admet-2684	352	34	j.	j.	PROPN
admet-2684	352	35	jampilek	jampilek	PROPN
admet-2684	352	36	.	.	PUNCT
admet-2684	353	1	antimycobacterial	antimycobacterial	ADJ
admet-2684	353	2	and	and	CCONJ
admet-2684	353	3	herbicidal	herbicidal	ADJ
admet-2684	353	4	activity	activity	NOUN
admet-2684	353	5	of	of	ADP
admet-2684	353	6	ring	ring	NOUN
admet-2684	353	7	-	-	PUNCT
admet-2684	353	8	substituted	substitute	VERB
admet-2684	353	9	1hydroxynaphthalene-2	1hydroxynaphthalene-2	NUM
admet-2684	353	10	-	-	PUNCT
admet-2684	353	11	carboxanilides	carboxanilide	NOUN
admet-2684	353	12	.	.	PUNCT
admet-2684	354	1	bioorganic	bioorganic	ADJ
admet-2684	354	2	and	and	CCONJ
admet-2684	354	3	medicinal	medicinal	ADJ
admet-2684	354	4	chemistry	chemistry	NOUN
admet-2684	354	5	21	21	NUM
admet-2684	354	6	(	(	PUNCT
admet-2684	354	7	2013	2013	NUM
admet-2684	354	8	)	)	PUNCT
admet-2684	354	9	6531	6531	NUM
admet-2684	354	10	-	-	SYM
admet-2684	354	11	6541	6541	NUM
admet-2684	354	12	.	.	PUNCT
admet-2684	355	1	https://doi.org/10.1016/j.bmc.2013.08.030	https://doi.org/10.1016/j.bmc.2013.08.030	NOUN
admet-2684	356	1	[	[	X
admet-2684	356	2	30	30	NUM
admet-2684	356	3	]	]	PUNCT
admet-2684	356	4	t.	t.	PROPN
admet-2684	356	5	gonec	gonec	PROPN
admet-2684	356	6	,	,	PUNCT
admet-2684	356	7	s.	s.	PROPN
admet-2684	356	8	pospisilova	pospisilova	PROPN
admet-2684	356	9	,	,	PUNCT
admet-2684	356	10	t.	t.	PROPN
admet-2684	356	11	kauerova	kauerova	PROPN
admet-2684	356	12	,	,	PUNCT
admet-2684	356	13	j.	j.	PROPN
admet-2684	356	14	kos	kos	PROPN
admet-2684	356	15	,	,	PUNCT
admet-2684	356	16	j.	j.	PROPN
admet-2684	356	17	dohanosova	dohanosova	PROPN
admet-2684	356	18	,	,	PUNCT
admet-2684	356	19	m.	m.	NOUN
admet-2684	356	20	oravec	oravec	PROPN
admet-2684	356	21	,	,	PUNCT
admet-2684	356	22	p.	p.	NOUN
admet-2684	356	23	kollar	kollar	PROPN
admet-2684	356	24	,	,	PUNCT
admet-2684	356	25	a.	a.	NOUN
admet-2684	356	26	coffey	coffey	PROPN
admet-2684	356	27	,	,	PUNCT
admet-2684	356	28	t.	t.	PROPN
admet-2684	356	29	liptaj	liptaj	PROPN
admet-2684	356	30	,	,	PUNCT
admet-2684	356	31	a.	a.	NOUN
admet-2684	356	32	cizek	cizek	PROPN
admet-2684	356	33	,	,	PUNCT
admet-2684	356	34	j.	j.	PROPN
admet-2684	356	35	jampilek	jampilek	PROPN
admet-2684	356	36	.	.	PUNCT
admet-2684	357	1	n	n	X
admet-2684	357	2	-	-	PUNCT
admet-2684	357	3	alkoxyphenylhydroxynaphthalenecarboxamides	alkoxyphenylhydroxynaphthalenecarboxamide	NOUN
admet-2684	357	4	and	and	CCONJ
admet-2684	357	5	their	their	PRON
admet-2684	357	6	antimycobacterial	antimycobacterial	ADJ
admet-2684	357	7	activity	activity	NOUN
admet-2684	357	8	.	.	PUNCT
admet-2684	358	1	molecules	molecule	NOUN
admet-2684	358	2	21	21	NUM
admet-2684	358	3	(	(	PUNCT
admet-2684	358	4	2016	2016	NUM
admet-2684	358	5	)	)	PUNCT
admet-2684	358	6	1068	1068	NUM
admet-2684	358	7	.	.	PUNCT
admet-2684	359	1	https://doi.org/10.3390/molecules21081068	https://doi.org/10.3390/molecules21081068	VERB
admet-2684	359	2	[	[	X
admet-2684	359	3	31	31	NUM
admet-2684	359	4	]	]	PUNCT
admet-2684	359	5	h.	h.	PROPN
admet-2684	359	6	michnova	michnova	PROPN
admet-2684	359	7	,	,	PUNCT
admet-2684	359	8	s.	s.	PROPN
admet-2684	359	9	pospisilova	pospisilova	AUX
admet-2684	359	10	,	,	PUNCT
admet-2684	359	11	t.	t.	PROPN
admet-2684	359	12	gonec	gonec	PROPN
admet-2684	359	13	,	,	PUNCT
admet-2684	359	14	i.	i.	PROPN
admet-2684	359	15	kapustikova	kapustikova	PROPN
admet-2684	359	16	,	,	PUNCT
admet-2684	359	17	p.	p.	PROPN
admet-2684	359	18	kollar	kollar	PROPN
admet-2684	359	19	,	,	PUNCT
admet-2684	359	20	v.	v.	ADP
admet-2684	359	21	kozik	kozik	PROPN
admet-2684	359	22	,	,	PUNCT
admet-2684	359	23	r.	r.	PROPN
admet-2684	359	24	musiol	musiol	PROPN
admet-2684	359	25	,	,	PUNCT
admet-2684	359	26	i.	i.	PROPN
admet-2684	359	27	jendrzejewska	jendrzejewska	PROPN
admet-2684	359	28	,	,	PUNCT
admet-2684	359	29	j.	j.	PROPN
admet-2684	359	30	vanco	vanco	PROPN
admet-2684	359	31	,	,	PUNCT
admet-2684	359	32	z.	z.	PROPN
admet-2684	359	33	travnicek	travnicek	PROPN
admet-2684	359	34	,	,	PUNCT
admet-2684	359	35	a.	a.	NOUN
admet-2684	359	36	cizek	cizek	PROPN
admet-2684	359	37	,	,	PUNCT
admet-2684	359	38	a.	a.	NOUN
admet-2684	359	39	bak	bak	PROPN
admet-2684	359	40	,	,	PUNCT
admet-2684	359	41	j.	j.	PROPN
admet-2684	359	42	jampilek	jampilek	PROPN
admet-2684	359	43	.	.	PUNCT
admet-2684	360	1	bioactivity	bioactivity	NOUN
admet-2684	360	2	of	of	ADP
admet-2684	360	3	methoxylated	methoxylate	VERB
admet-2684	360	4	and	and	CCONJ
admet-2684	360	5	methylated	methylate	VERB
admet-2684	360	6	1hydroxynaphthalene-2	1hydroxynaphthalene-2	NUM
admet-2684	360	7	-	-	PUNCT
admet-2684	360	8	carboxanilides	carboxanilide	NOUN
admet-2684	360	9	:	:	PUNCT
admet-2684	360	10	comparative	comparative	ADJ
admet-2684	360	11	molecular	molecular	ADJ
admet-2684	360	12	surface	surface	NOUN
admet-2684	360	13	analysis	analysis	NOUN
admet-2684	360	14	.	.	PUNCT
admet-2684	361	1	molecules	molecule	NOUN
admet-2684	361	2	24	24	NUM
admet-2684	361	3	(	(	PUNCT
admet-2684	361	4	2019	2019	NUM
admet-2684	361	5	)	)	PUNCT
admet-2684	361	6	2991	2991	NUM
admet-2684	361	7	.	.	PUNCT
admet-2684	362	1	https://doi.org/10.3390/molecules24162991	https://doi.org/10.3390/molecules24162991	PROPN
admet-2684	362	2	[	[	X
admet-2684	362	3	32	32	NUM
admet-2684	362	4	]	]	PUNCT
admet-2684	362	5	e.	e.	PROPN
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admet-2684	362	7	,	,	PUNCT
admet-2684	362	8	a.	a.	NOUN
admet-2684	362	9	mrozek	mrozek	NOUN
admet-2684	362	10	-	-	PUNCT
admet-2684	362	11	wilczkiewicz	wilczkiewicz	NOUN
admet-2684	362	12	,	,	PUNCT
admet-2684	362	13	k.	k.	PROPN
admet-2684	362	14	malarz	malarz	PROPN
admet-2684	362	15	,	,	PUNCT
admet-2684	362	16	j.	j.	PROPN
admet-2684	362	17	kos	kos	PROPN
admet-2684	362	18	,	,	PUNCT
admet-2684	362	19	t.	t.	PROPN
admet-2684	362	20	gonec	gonec	PROPN
admet-2684	362	21	,	,	PUNCT
admet-2684	362	22	m.	m.	NOUN
admet-2684	362	23	oravec	oravec	PROPN
admet-2684	362	24	,	,	PUNCT
admet-2684	362	25	r.	r.	PROPN
admet-2684	362	26	gawecki	gawecki	PROPN
admet-2684	362	27	,	,	PUNCT
admet-2684	362	28	a.	a.	NOUN
admet-2684	362	29	bak	bak	PROPN
admet-2684	362	30	,	,	PUNCT
admet-2684	362	31	j.	j.	PROPN
admet-2684	362	32	dohanosova	dohanosova	PROPN
admet-2684	362	33	,	,	PUNCT
admet-2684	362	34	i.	i.	PROPN
admet-2684	362	35	kapustikova	kapustikova	PROPN
admet-2684	362	36	,	,	PUNCT
admet-2684	362	37	t.	t.	PROPN
admet-2684	362	38	liptaj	liptaj	PROPN
admet-2684	362	39	,	,	PUNCT
admet-2684	362	40	j.	j.	PROPN
admet-2684	362	41	jampilek	jampilek	PROPN
admet-2684	362	42	,	,	PUNCT
admet-2684	362	43	r.	r.	PROPN
admet-2684	362	44	musiol	musiol	PROPN
admet-2684	362	45	.	.	PUNCT
admet-2684	363	1	design	design	NOUN
admet-2684	363	2	and	and	CCONJ
admet-2684	363	3	synthesis	synthesis	NOUN
admet-2684	363	4	of	of	ADP
admet-2684	363	5	anti	anti	ADJ
admet-2684	363	6	-	-	ADJ
admet-2684	363	7	cancer	cancer	ADJ
admet-2684	363	8	1hydroxynaphthalene-2	1hydroxynaphthalene-2	NUM
admet-2684	363	9	-	-	PUNCT
admet-2684	363	10	carboxanilides	carboxanilide	NOUN
admet-2684	363	11	with	with	ADP
admet-2684	363	12	a	a	DET
admet-2684	363	13	p53	p53	NOUN
admet-2684	363	14	independent	independent	ADJ
admet-2684	363	15	mechanism	mechanism	NOUN
admet-2684	363	16	of	of	ADP
admet-2684	363	17	action	action	NOUN
admet-2684	363	18	.	.	PUNCT
admet-2684	364	1	scientific	scientific	ADJ
admet-2684	364	2	reports	report	NOUN
admet-2684	364	3	9	9	NUM
admet-2684	364	4	(	(	PUNCT
admet-2684	364	5	2019	2019	NUM
admet-2684	364	6	)	)	PUNCT
admet-2684	364	7	6387	6387	NUM
admet-2684	364	8	.	.	PUNCT
admet-2684	365	1	https://doi.org/10.1038/s41598-019-42595-y	https://doi.org/10.1038/s41598-019-42595-y	PROPN
admet-2684	366	1	[	[	X
admet-2684	366	2	33	33	NUM
admet-2684	366	3	]	]	PUNCT
admet-2684	366	4	t.	t.	PROPN
admet-2684	366	5	kauerova	kauerova	PROPN
admet-2684	366	6	,	,	PUNCT
admet-2684	366	7	t.	t.	PROPN
admet-2684	366	8	gonec	gonec	PROPN
admet-2684	366	9	,	,	PUNCT
admet-2684	366	10	j.	j.	PROPN
admet-2684	366	11	jampilek	jampilek	PROPN
admet-2684	366	12	,	,	PUNCT
admet-2684	366	13	s.	s.	PROPN
admet-2684	366	14	hafner	hafner	PROPN
admet-2684	366	15	,	,	PUNCT
admet-2684	366	16	a.k	a.k	PROPN
admet-2684	366	17	.	.	PROPN
admet-2684	366	18	gaiser	gaiser	PROPN
admet-2684	366	19	,	,	PUNCT
admet-2684	366	20	t.	t.	PROPN
admet-2684	366	21	syrovets	syrovets	PROPN
admet-2684	366	22	,	,	PUNCT
admet-2684	366	23	r.	r.	PROPN
admet-2684	366	24	fedr	fedr	PROPN
admet-2684	366	25	,	,	PUNCT
admet-2684	366	26	k.	k.	PROPN
admet-2684	366	27	soucek	soucek	PROPN
admet-2684	366	28	,	,	PUNCT
admet-2684	366	29	p.	p.	NOUN
admet-2684	366	30	kollar	kollar	PROPN
admet-2684	366	31	.	.	PUNCT
admet-2684	367	1	ring	ring	NOUN
admet-2684	367	2	-	-	PUNCT
admet-2684	367	3	substituted	substitute	VERB
admet-2684	367	4	1	1	NUM
admet-2684	367	5	-	-	PUNCT
admet-2684	367	6	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	367	7	-	-	PUNCT
admet-2684	367	8	carboxanilides	carboxanilide	NOUN
admet-2684	367	9	inhibit	inhibit	VERB
admet-2684	367	10	proliferation	proliferation	NOUN
admet-2684	367	11	and	and	CCONJ
admet-2684	367	12	trigger	trigger	NOUN
admet-2684	367	13	mitochondria	mitochondria	NOUN
admet-2684	367	14	-	-	PUNCT
admet-2684	367	15	mediated	mediate	VERB
admet-2684	367	16	apoptosis	apoptosis	NOUN
admet-2684	367	17	.	.	PUNCT
admet-2684	368	1	international	international	ADJ
admet-2684	368	2	journal	journal	NOUN
admet-2684	368	3	of	of	ADP
admet-2684	368	4	molecular	molecular	ADJ
admet-2684	368	5	sciences	science	NOUN
admet-2684	368	6	21	21	NUM
admet-2684	368	7	(	(	PUNCT
admet-2684	368	8	2020	2020	NUM
admet-2684	368	9	)	)	PUNCT
admet-2684	368	10	3416	3416	NUM
admet-2684	368	11	.	.	PUNCT
admet-2684	369	1	https://doi.org/10.3390/ijms21103416	https://doi.org/10.3390/ijms21103416	VERB
admet-2684	370	1	[	[	X
admet-2684	370	2	34	34	NUM
admet-2684	370	3	]	]	X
admet-2684	370	4	h.	h.	PROPN
admet-2684	370	5	terada	terada	PROPN
admet-2684	370	6	,	,	PUNCT
admet-2684	370	7	s.	s.	PROPN
admet-2684	370	8	goto	goto	PROPN
admet-2684	370	9	,	,	PUNCT
admet-2684	370	10	k.	k.	PROPN
admet-2684	370	11	yamamoto	yamamoto	PROPN
admet-2684	370	12	,	,	PUNCT
admet-2684	370	13	i.	i.	PROPN
admet-2684	370	14	takeuchi	takeuchi	PROPN
admet-2684	370	15	,	,	PUNCT
admet-2684	370	16	y.	y.	PROPN
admet-2684	370	17	hamada	hamada	PROPN
admet-2684	370	18	,	,	PUNCT
admet-2684	370	19	k.	k.	PROPN
admet-2684	370	20	miyake	miyake	PROPN
admet-2684	370	21	.	.	PUNCT
admet-2684	371	1	structural	structural	ADJ
admet-2684	371	2	requirements	requirement	NOUN
admet-2684	371	3	of	of	ADP
admet-2684	371	4	salicylanilides	salicylanilide	NOUN
admet-2684	371	5	for	for	ADP
admet-2684	371	6	uncoupling	uncouple	VERB
admet-2684	371	7	activity	activity	NOUN
admet-2684	371	8	in	in	ADP
admet-2684	371	9	mitochondria	mitochondria	NOUN
admet-2684	371	10	:	:	PUNCT
admet-2684	371	11	quantitative	quantitative	ADJ
admet-2684	371	12	analysis	analysis	NOUN
admet-2684	371	13	of	of	ADP
admet-2684	371	14	structure	structure	NOUN
admet-2684	371	15	-	-	PUNCT
admet-2684	371	16	uncoupling	uncouple	VERB
admet-2684	371	17	relationships	relationship	NOUN
admet-2684	371	18	.	.	PUNCT
admet-2684	372	1	biochimica	biochimica	PROPN
admet-2684	372	2	et	et	PROPN
admet-2684	372	3	biophysica	biophysica	PROPN
admet-2684	372	4	acta	acta	PROPN
admet-2684	372	5	936	936	NUM
admet-2684	372	6	(	(	PUNCT
admet-2684	372	7	1988	1988	NUM
admet-2684	372	8	)	)	PUNCT
admet-2684	372	9	504	504	NUM
admet-2684	372	10	-	-	SYM
admet-2684	372	11	512	512	NUM
admet-2684	372	12	.	.	PUNCT
admet-2684	373	1	https://doi.org/10.1016/00052728(88)90027-8	https://doi.org/10.1016/00052728(88)90027-8	ADJ
admet-2684	373	2	[	[	X
admet-2684	373	3	35	35	NUM
admet-2684	373	4	]	]	X
admet-2684	373	5	i.y	i.y	PROPN
admet-2684	373	6	.	.	PROPN
admet-2684	373	7	lee	lee	PROPN
admet-2684	373	8	,	,	PUNCT
admet-2684	373	9	t.d	t.d	PROPN
admet-2684	373	10	.	.	PROPN
admet-2684	373	11	gruber	gruber	PROPN
admet-2684	373	12	,	,	PUNCT
admet-2684	373	13	a.	a.	PROPN
admet-2684	373	14	samuels	samuels	PROPN
admet-2684	373	15	,	,	PUNCT
admet-2684	373	16	m.	m.	NOUN
admet-2684	373	17	yun	yun	PROPN
admet-2684	373	18	,	,	PUNCT
admet-2684	373	19	b.	b.	PROPN
admet-2684	373	20	nam	nam	PROPN
admet-2684	373	21	,	,	PUNCT
admet-2684	373	22	m.	m.	PROPN
admet-2684	373	23	kang	kang	PROPN
admet-2684	373	24	,	,	PUNCT
admet-2684	373	25	k.	k.	PROPN
admet-2684	373	26	crowley	crowley	PROPN
admet-2684	373	27	,	,	PUNCT
admet-2684	373	28	b.	b.	PROPN
admet-2684	373	29	winterroth	winterroth	PROPN
admet-2684	373	30	,	,	PUNCT
admet-2684	373	31	h.i	h.i	PROPN
admet-2684	373	32	.	.	PROPN
admet-2684	373	33	boshoff	boshoff	PROPN
admet-2684	373	34	,	,	PUNCT
admet-2684	373	35	c.e	c.e	PROPN
admet-2684	373	36	.	.	PROPN
admet-2684	373	37	barry	barry	PROPN
admet-2684	373	38	.	.	PUNCT
admet-2684	373	39	structure	structure	NOUN
admet-2684	373	40	-	-	PUNCT
admet-2684	373	41	activity	activity	NOUN
admet-2684	373	42	relationships	relationship	NOUN
admet-2684	373	43	of	of	ADP
admet-2684	373	44	antitubercular	antitubercular	ADJ
admet-2684	373	45	salicylanilides	salicylanilide	NOUN
admet-2684	373	46	consistent	consistent	ADJ
admet-2684	373	47	with	with	ADP
admet-2684	373	48	disruption	disruption	NOUN
admet-2684	373	49	https://doi.org/10.1016/j.ejpb.2022.03.009	https://doi.org/10.1016/j.ejpb.2022.03.009	PROPN
admet-2684	373	50	https://doi.org/10.1016/j.bmc.2017.01.016	https://doi.org/10.1016/j.bmc.2017.01.016	PROPN
admet-2684	373	51	https://doi.org/10.1128/aac.01225-19	https://doi.org/10.1128/aac.01225-19	PROPN
admet-2684	373	52	https://doi.org/10.1038/s41598-023-41442-5	https://doi.org/10.1038/s41598-023-41442-5	PART
admet-2684	373	53	https://doi.org/10.1111/febs.16915	https://doi.org/10.1111/febs.16915	NOUN
admet-2684	373	54	https://doi.org/10.3390/ijms24021728	https://doi.org/10.3390/ijms24021728	NOUN
admet-2684	373	55	https://doi.org/10.3390/molecules15118122	https://doi.org/10.3390/molecules15118122	PROPN
admet-2684	373	56	https://doi.org/10.1016/j.bmcl.2011.05.118	https://doi.org/10.1016/j.bmcl.2011.05.118	PROPN
admet-2684	373	57	https://doi.org/10.1016/j.bmc.2013.08.030	https://doi.org/10.1016/j.bmc.2013.08.030	PROPN
admet-2684	373	58	https://doi.org/10.3390/molecules21081068	https://doi.org/10.3390/molecules21081068	VERB
admet-2684	373	59	https://doi.org/10.3390/molecules24162991	https://doi.org/10.3390/molecules24162991	PROPN
admet-2684	373	60	https://doi.org/10.1038/s41598-019-42595-y	https://doi.org/10.1038/s41598-019-42595-y	PROPN
admet-2684	373	61	https://doi.org/10.3390/ijms21103416	https://doi.org/10.3390/ijms21103416	PROPN
admet-2684	373	62	https://doi.org/10.1016/0005-2728(88)90027-8	https://doi.org/10.1016/0005-2728(88)90027-8	PROPN
admet-2684	373	63	https://doi.org/10.1016/0005-2728(88)90027-8	https://doi.org/10.1016/0005-2728(88)90027-8	PROPN
admet-2684	373	64	admet	admet	PROPN
admet-2684	373	65	&	&	CCONJ
admet-2684	373	66	dmpk	dmpk	PROPN
admet-2684	373	67	13(2	13(2	PROPN
admet-2684	373	68	)	)	PUNCT
admet-2684	373	69	(	(	PUNCT
admet-2684	373	70	2025	2025	NUM
admet-2684	373	71	)	)	PUNCT
admet-2684	373	72	2684	2684	NUM
admet-2684	373	73	antistaphylococcal	antistaphylococcal	ADJ
admet-2684	373	74	effect	effect	NOUN
admet-2684	373	75	of	of	ADP
admet-2684	373	76	chlorinated	chlorinate	VERB
admet-2684	373	77	1	1	NUM
admet-2684	373	78	-	-	PUNCT
admet-2684	373	79	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	373	80	-	-	PUNCT
admet-2684	373	81	carboxanilides	carboxanilide	NOUN
admet-2684	373	82	doi	doi	NOUN
admet-2684	373	83	:	:	PUNCT
admet-2684	373	84	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	373	85	15	15	NUM
admet-2684	373	86	of	of	ADP
admet-2684	373	87	the	the	DET
admet-2684	373	88	proton	proton	NOUN
admet-2684	373	89	gradient	gradient	NOUN
admet-2684	373	90	via	via	ADP
admet-2684	373	91	proton	proton	NOUN
admet-2684	373	92	shuttling	shuttling	NOUN
admet-2684	373	93	.	.	PUNCT
admet-2684	374	1	bioorganic	bioorganic	ADJ
admet-2684	374	2	and	and	CCONJ
admet-2684	374	3	medicinal	medicinal	ADJ
admet-2684	374	4	chemistry	chemistry	NOUN
admet-2684	374	5	21	21	NUM
admet-2684	374	6	(	(	PUNCT
admet-2684	374	7	2013	2013	NUM
admet-2684	374	8	)	)	PUNCT
admet-2684	374	9	114	114	NUM
admet-2684	374	10	-	-	SYM
admet-2684	374	11	126	126	NUM
admet-2684	374	12	.	.	PUNCT
admet-2684	374	13	https://doi.org/10.1016/j.bmc.2012.10.056	https://doi.org/10.1016/j.bmc.2012.10.056	PROPN
admet-2684	375	1	[	[	X
admet-2684	375	2	36	36	NUM
admet-2684	375	3	]	]	X
admet-2684	375	4	m.j	m.j	PROPN
admet-2684	375	5	.	.	PROPN
admet-2684	375	6	macielag	macielag	PROPN
admet-2684	375	7	,	,	PUNCT
admet-2684	375	8	j.p	j.p	PROPN
admet-2684	375	9	.	.	PROPN
admet-2684	375	10	demers	demers	PROPN
admet-2684	375	11	,	,	PUNCT
admet-2684	375	12	s.a	s.a	PROPN
admet-2684	375	13	.	.	PROPN
admet-2684	375	14	fraga	fraga	PROPN
admet-2684	375	15	-	-	PUNCT
admet-2684	375	16	spano	spano	PROPN
admet-2684	375	17	,	,	PUNCT
admet-2684	375	18	d.j	d.j	PROPN
admet-2684	375	19	.	.	PROPN
admet-2684	375	20	hlasta	hlasta	PROPN
admet-2684	375	21	,	,	PUNCT
admet-2684	375	22	s.g	s.g	PROPN
admet-2684	375	23	.	.	PROPN
admet-2684	375	24	johnson	johnson	PROPN
admet-2684	375	25	,	,	PUNCT
admet-2684	375	26	r.m	r.m	PROPN
admet-2684	375	27	.	.	PROPN
admet-2684	375	28	kanojia	kanojia	PROPN
admet-2684	375	29	,	,	PUNCT
admet-2684	375	30	r.k	r.k	PROPN
admet-2684	375	31	.	.	PROPN
admet-2684	375	32	russell	russell	PROPN
admet-2684	375	33	,	,	PUNCT
admet-2684	375	34	z.	z.	PROPN
admet-2684	375	35	sui	sui	PROPN
admet-2684	375	36	,	,	PUNCT
admet-2684	375	37	m.a	m.a	PROPN
admet-2684	375	38	.	.	PROPN
admet-2684	375	39	weidner	weidner	PROPN
admet-2684	375	40	-	-	PUNCT
admet-2684	375	41	wells	wells	PROPN
admet-2684	375	42	,	,	PUNCT
admet-2684	375	43	h.	h.	PROPN
admet-2684	375	44	werblood	werblood	PROPN
admet-2684	375	45	,	,	PUNCT
admet-2684	375	46	b.d	b.d	PROPN
admet-2684	375	47	.	.	PROPN
admet-2684	375	48	foleno	foleno	PROPN
admet-2684	375	49	,	,	PUNCT
admet-2684	375	50	r.m	r.m	PROPN
admet-2684	375	51	.	.	PROPN
admet-2684	375	52	goldschmidt	goldschmidt	PROPN
admet-2684	375	53	,	,	PUNCT
admet-2684	375	54	m.j	m.j	PROPN
admet-2684	375	55	.	.	PROPN
admet-2684	375	56	loeloff	loeloff	PROPN
admet-2684	375	57	,	,	PUNCT
admet-2684	375	58	g.c	g.c	PROPN
admet-2684	375	59	.	.	PROPN
admet-2684	375	60	webb	webb	PROPN
admet-2684	375	61	,	,	PUNCT
admet-2684	375	62	j.f	j.f	PROPN
admet-2684	375	63	.	.	PROPN
admet-2684	375	64	barrett	barrett	PROPN
admet-2684	375	65	.	.	PROPN
admet-2684	375	66	substituted	substitute	VERB
admet-2684	375	67	salicylanilides	salicylanilide	NOUN
admet-2684	375	68	as	as	ADP
admet-2684	375	69	inhibitors	inhibitor	NOUN
admet-2684	375	70	of	of	ADP
admet-2684	375	71	two	two	NUM
admet-2684	375	72	-	-	PUNCT
admet-2684	375	73	component	component	NOUN
admet-2684	375	74	regulatory	regulatory	ADJ
admet-2684	375	75	systems	system	NOUN
admet-2684	375	76	in	in	ADP
admet-2684	375	77	bacteria	bacteria	NOUN
admet-2684	375	78	.	.	PUNCT
admet-2684	376	1	journal	journal	PROPN
admet-2684	376	2	of	of	ADP
admet-2684	376	3	medicinal	medicinal	ADJ
admet-2684	376	4	chemistry	chemistry	NOUN
admet-2684	376	5	41	41	NUM
admet-2684	376	6	(	(	PUNCT
admet-2684	376	7	1998	1998	NUM
admet-2684	376	8	)	)	PUNCT
admet-2684	376	9	2939	2939	NUM
admet-2684	376	10	-	-	SYM
admet-2684	376	11	2945	2945	NUM
admet-2684	376	12	.	.	PUNCT
admet-2684	377	1	https://doi.org/10.1021/jm9803572	https://doi.org/10.1021/jm9803572	PRON
admet-2684	377	2	[	[	X
admet-2684	377	3	37	37	NUM
admet-2684	377	4	]	]	X
admet-2684	377	5	n.	n.	PROPN
admet-2684	377	6	dasgupta	dasgupta	PROPN
admet-2684	377	7	,	,	PUNCT
admet-2684	377	8	v.	v.	PROPN
admet-2684	377	9	kapur	kapur	PROPN
admet-2684	377	10	,	,	PUNCT
admet-2684	377	11	k.k	k.k	PROPN
admet-2684	377	12	.	.	PROPN
admet-2684	377	13	singh	singh	PROPN
admet-2684	377	14	,	,	PUNCT
admet-2684	377	15	t.k	t.k	PROPN
admet-2684	377	16	.	.	PROPN
admet-2684	377	17	das	das	PROPN
admet-2684	377	18	,	,	PUNCT
admet-2684	377	19	s.	s.	PROPN
admet-2684	377	20	sachdeva	sachdeva	PROPN
admet-2684	377	21	,	,	PUNCT
admet-2684	377	22	k.	k.	PROPN
admet-2684	377	23	jyothisri	jyothisri	PROPN
admet-2684	377	24	,	,	PUNCT
admet-2684	377	25	j.s	j.s	PROPN
admet-2684	377	26	.	.	PROPN
admet-2684	377	27	tyagi	tyagi	PROPN
admet-2684	377	28	.	.	PUNCT
admet-2684	378	1	characterization	characterization	NOUN
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admet-2684	378	3	a	a	DET
admet-2684	378	4	two	two	NUM
admet-2684	378	5	-	-	PUNCT
admet-2684	378	6	component	component	NOUN
admet-2684	378	7	system	system	NOUN
admet-2684	378	8	,	,	PUNCT
admet-2684	378	9	devr	devr	NOUN
admet-2684	378	10	-	-	PUNCT
admet-2684	378	11	devs	devs	NOUN
admet-2684	378	12	,	,	PUNCT
admet-2684	378	13	of	of	ADP
admet-2684	378	14	mycobacterium	mycobacterium	NOUN
admet-2684	378	15	tuberculosis	tuberculosis	NOUN
admet-2684	378	16	.	.	PUNCT
admet-2684	379	1	tubercle	tubercle	NOUN
admet-2684	379	2	and	and	CCONJ
admet-2684	379	3	lung	lung	NOUN
admet-2684	379	4	disease	disease	NOUN
admet-2684	379	5	80	80	NUM
admet-2684	379	6	(	(	PUNCT
admet-2684	379	7	2000	2000	NUM
admet-2684	379	8	)	)	PUNCT
admet-2684	379	9	141	141	NUM
admet-2684	379	10	-	-	SYM
admet-2684	379	11	159	159	NUM
admet-2684	379	12	.	.	PUNCT
admet-2684	380	1	https://doi.org/10.1054/tuld.2000.0240	https://doi.org/10.1054/tuld.2000.0240	PROPN
admet-2684	380	2	[	[	X
admet-2684	380	3	38	38	NUM
admet-2684	380	4	]	]	X
admet-2684	380	5	r.e	r.e	PROPN
admet-2684	380	6	.	.	PROPN
admet-2684	380	7	moellering	moellering	PROPN
admet-2684	380	8	,	,	PUNCT
admet-2684	380	9	b.f	b.f	PROPN
admet-2684	380	10	.	.	PROPN
admet-2684	380	11	cravatt	cravatt	PROPN
admet-2684	380	12	.	.	PUNCT
admet-2684	381	1	how	how	SCONJ
admet-2684	381	2	chemoproteomics	chemoproteomic	NOUN
admet-2684	381	3	can	can	AUX
admet-2684	381	4	enable	enable	VERB
admet-2684	381	5	drug	drug	NOUN
admet-2684	381	6	discovery	discovery	NOUN
admet-2684	381	7	and	and	CCONJ
admet-2684	381	8	development	development	NOUN
admet-2684	381	9	.	.	PUNCT
admet-2684	382	1	chemical	chemical	ADJ
admet-2684	382	2	biology	biology	NOUN
admet-2684	382	3	19	19	NUM
admet-2684	382	4	(	(	PUNCT
admet-2684	382	5	2012	2012	NUM
admet-2684	382	6	)	)	PUNCT
admet-2684	382	7	11	11	NUM
admet-2684	382	8	-	-	SYM
admet-2684	382	9	22	22	NUM
admet-2684	382	10	.	.	PUNCT
admet-2684	383	1	https://doi.org/10.1016/j.chembiol.2012.01.001	https://doi.org/10.1016/j.chembiol.2012.01.001	PROPN
admet-2684	383	2	[	[	X
admet-2684	383	3	39	39	NUM
admet-2684	383	4	]	]	X
admet-2684	383	5	k.p	k.p	PROPN
admet-2684	383	6	.	.	PROPN
admet-2684	383	7	malarney	malarney	PROPN
admet-2684	383	8	,	,	PUNCT
admet-2684	383	9	p.v	p.v	PROPN
admet-2684	383	10	.	.	PROPN
admet-2684	383	11	chang	chang	PROPN
admet-2684	383	12	.	.	PUNCT
admet-2684	384	1	chemoproteomic	chemoproteomic	ADJ
admet-2684	384	2	approaches	approach	NOUN
admet-2684	384	3	for	for	ADP
admet-2684	384	4	unraveling	unravel	VERB
admet-2684	384	5	prokaryotic	prokaryotic	ADJ
admet-2684	384	6	biology	biology	NOUN
admet-2684	384	7	.	.	PUNCT
admet-2684	385	1	israel	israel	PROPN
admet-2684	385	2	journal	journal	PROPN
admet-2684	385	3	of	of	ADP
admet-2684	385	4	chemistry	chemistry	PROPN
admet-2684	385	5	63	63	NUM
admet-2684	385	6	(	(	PUNCT
admet-2684	385	7	2023	2023	NUM
admet-2684	385	8	)	)	PUNCT
admet-2684	385	9	e202200076	e202200076	NOUN
admet-2684	385	10	.	.	PUNCT
admet-2684	386	1	https://doi.org/10.1002/ijch.202200076	https://doi.org/10.1002/ijch.202200076	PROPN
admet-2684	387	1	[	[	X
admet-2684	387	2	40	40	NUM
admet-2684	387	3	]	]	PUNCT
admet-2684	387	4	g.	g.	PROPN
admet-2684	387	5	drewes	drewes	PROPN
admet-2684	387	6	,	,	PUNCT
admet-2684	387	7	s.	s.	PROPN
admet-2684	387	8	knapp	knapp	PROPN
admet-2684	387	9	.	.	PUNCT
admet-2684	388	1	chemoproteomics	chemoproteomic	NOUN
admet-2684	388	2	and	and	CCONJ
admet-2684	388	3	chemical	chemical	NOUN
admet-2684	388	4	probes	probe	NOUN
admet-2684	388	5	for	for	ADP
admet-2684	388	6	target	target	NOUN
admet-2684	388	7	discovery	discovery	NOUN
admet-2684	388	8	.	.	PUNCT
admet-2684	389	1	trends	trend	NOUN
admet-2684	389	2	in	in	ADP
admet-2684	389	3	biotechnology	biotechnology	NOUN
admet-2684	389	4	36	36	NUM
admet-2684	389	5	(	(	PUNCT
admet-2684	389	6	2018	2018	NUM
admet-2684	389	7	)	)	PUNCT
admet-2684	389	8	1275	1275	NUM
admet-2684	389	9	-	-	SYM
admet-2684	389	10	1286	1286	NUM
admet-2684	389	11	.	.	PUNCT
admet-2684	390	1	https://doi.org/10.1016/j.tibtech.2018.06.008	https://doi.org/10.1016/j.tibtech.2018.06.008	NOUN
admet-2684	391	1	[	[	X
admet-2684	391	2	41	41	NUM
admet-2684	391	3	]	]	X
admet-2684	391	4	l.h	l.h	PROPN
admet-2684	391	5	.	.	PROPN
admet-2684	391	6	jones	jones	PROPN
admet-2684	391	7	,	,	PUNCT
admet-2684	391	8	h.	h.	PROPN
admet-2684	391	9	neubert	neubert	PROPN
admet-2684	391	10	.	.	PUNCT
admet-2684	392	1	clinical	clinical	ADJ
admet-2684	392	2	chemoproteomics	chemoproteomic	NOUN
admet-2684	392	3	—	—	PUNCT
admet-2684	392	4	opportunities	opportunity	NOUN
admet-2684	392	5	and	and	CCONJ
admet-2684	392	6	obstacles	obstacle	NOUN
admet-2684	392	7	.	.	PUNCT
admet-2684	393	1	science	science	NOUN
admet-2684	393	2	translational	translational	ADJ
admet-2684	393	3	medicine	medicine	NOUN
admet-2684	393	4	9	9	NUM
admet-2684	393	5	(	(	PUNCT
admet-2684	393	6	2017	2017	NUM
admet-2684	393	7	)	)	PUNCT
admet-2684	393	8	7951	7951	NUM
admet-2684	393	9	.	.	PUNCT
admet-2684	394	1	https://doi.org/10.1126/scitranslmed.aaf7951	https://doi.org/10.1126/scitranslmed.aaf7951	NOUN
admet-2684	394	2	[	[	X
admet-2684	394	3	42	42	NUM
admet-2684	394	4	]	]	PUNCT
admet-2684	394	5	x.	x.	PROPN
admet-2684	394	6	chen	chen	PROPN
admet-2684	394	7	,	,	PUNCT
admet-2684	394	8	y.k	y.k	PROPN
admet-2684	394	9	.	.	PROPN
admet-2684	394	10	wong	wong	PROPN
admet-2684	394	11	,	,	PUNCT
admet-2684	394	12	j.	j.	PROPN
admet-2684	394	13	wang	wang	PROPN
admet-2684	394	14	,	,	PUNCT
admet-2684	394	15	j.	j.	PROPN
admet-2684	394	16	zhang	zhang	PROPN
admet-2684	394	17	,	,	PUNCT
admet-2684	394	18	y.	y.	PROPN
admet-2684	394	19	lee	lee	PROPN
admet-2684	394	20	,	,	PUNCT
admet-2684	394	21	h.	h.	PROPN
admet-2684	394	22	shen	shen	PROPN
admet-2684	394	23	,	,	PUNCT
admet-2684	394	24	q.	q.	PROPN
admet-2684	394	25	lin	lin	PROPN
admet-2684	394	26	,	,	PUNCT
admet-2684	394	27	z.c	z.c	PROPN
admet-2684	394	28	.	.	PROPN
admet-2684	394	29	hua	hua	PROPN
admet-2684	394	30	.	.	PROPN
admet-2684	395	1	target	target	NOUN
admet-2684	395	2	identification	identification	NOUN
admet-2684	395	3	with	with	ADP
admet-2684	395	4	quantitative	quantitative	ADJ
admet-2684	395	5	activity	activity	NOUN
admet-2684	395	6	based	base	VERB
admet-2684	395	7	protein	protein	NOUN
admet-2684	395	8	profiling	profiling	NOUN
admet-2684	395	9	(	(	PUNCT
admet-2684	395	10	abpp	abpp	ADJ
admet-2684	395	11	)	)	PUNCT
admet-2684	395	12	.	.	PUNCT
admet-2684	396	1	proteomics	proteomic	NOUN
admet-2684	396	2	17	17	NUM
admet-2684	396	3	(	(	PUNCT
admet-2684	396	4	2017	2017	NUM
admet-2684	396	5	)	)	PUNCT
admet-2684	396	6	1600212	1600212	NUM
admet-2684	396	7	.	.	PUNCT
admet-2684	397	1	https://doi.org/10.1002/pmic.201600212	https://doi.org/10.1002/pmic.201600212	PROPN
admet-2684	398	1	[	[	X
admet-2684	398	2	43	43	NUM
admet-2684	398	3	]	]	X
admet-2684	398	4	s.	s.	PROPN
admet-2684	398	5	wang	wang	PROPN
admet-2684	398	6	,	,	PUNCT
admet-2684	398	7	y.	y.	PROPN
admet-2684	398	8	tian	tian	PROPN
admet-2684	398	9	,	,	PUNCT
admet-2684	398	10	m.	m.	PROPN
admet-2684	398	11	wang	wang	PROPN
admet-2684	398	12	,	,	PUNCT
admet-2684	398	13	m.	m.	PROPN
admet-2684	398	14	wang	wang	PROPN
admet-2684	398	15	,	,	PUNCT
admet-2684	398	16	g.	g.	PROPN
admet-2684	398	17	sun	sun	PROPN
admet-2684	398	18	,	,	PUNCT
admet-2684	398	19	x.	x.	PROPN
admet-2684	398	20	sun	sun	PROPN
admet-2684	398	21	.	.	PUNCT
admet-2684	399	1	advanced	advanced	ADJ
admet-2684	399	2	activity	activity	NOUN
admet-2684	399	3	-	-	PUNCT
admet-2684	399	4	based	base	VERB
admet-2684	399	5	protein	protein	NOUN
admet-2684	399	6	profiling	profiling	NOUN
admet-2684	399	7	application	application	NOUN
admet-2684	399	8	strategies	strategy	NOUN
admet-2684	399	9	for	for	ADP
admet-2684	399	10	drug	drug	NOUN
admet-2684	399	11	development	development	NOUN
admet-2684	399	12	.	.	PUNCT
admet-2684	400	1	frontiers	frontier	NOUN
admet-2684	400	2	in	in	ADP
admet-2684	400	3	pharmacology	pharmacology	NOUN
admet-2684	400	4	9	9	NUM
admet-2684	400	5	(	(	PUNCT
admet-2684	400	6	2018	2018	NUM
admet-2684	400	7	)	)	PUNCT
admet-2684	400	8	353	353	NUM
admet-2684	400	9	.	.	PUNCT
admet-2684	401	1	https://doi.org/10.3389/fphar.2018.00353	https://doi.org/10.3389/fphar.2018.00353	PROPN
admet-2684	401	2	[	[	X
admet-2684	401	3	44	44	NUM
admet-2684	401	4	]	]	PUNCT
admet-2684	401	5	k.	k.	PROPN
admet-2684	401	6	naumann	naumann	PROPN
admet-2684	401	7	.	.	PUNCT
admet-2684	402	1	influence	influence	NOUN
admet-2684	402	2	of	of	ADP
admet-2684	402	3	chlorine	chlorine	NOUN
admet-2684	402	4	substituents	substituent	NOUN
admet-2684	402	5	on	on	ADP
admet-2684	402	6	biological	biological	ADJ
admet-2684	402	7	activity	activity	NOUN
admet-2684	402	8	of	of	ADP
admet-2684	402	9	chemicals	chemical	NOUN
admet-2684	402	10	:	:	PUNCT
admet-2684	402	11	a	a	DET
admet-2684	402	12	review	review	NOUN
admet-2684	402	13	.	.	PUNCT
admet-2684	403	1	pest	pest	NOUN
admet-2684	403	2	management	management	NOUN
admet-2684	403	3	science	science	NOUN
admet-2684	403	4	56	56	NUM
admet-2684	403	5	(	(	PUNCT
admet-2684	403	6	2000	2000	NUM
admet-2684	403	7	)	)	PUNCT
admet-2684	403	8	3	3	NUM
admet-2684	403	9	-	-	SYM
admet-2684	403	10	21	21	NUM
admet-2684	403	11	.	.	PUNCT
admet-2684	404	1	https://doi.org/10.1002/(sici)15264998(200001)56:1%3c3::aid-ps107%3e3.0.co;2-p	https://doi.org/10.1002/(sici)15264998(200001)56:1%3c3::aid-ps107%3e3.0.co;2-p	PRON
admet-2684	405	1	[	[	X
admet-2684	405	2	45	45	NUM
admet-2684	405	3	]	]	X
admet-2684	405	4	w.y	w.y	PROPN
admet-2684	405	5	.	.	PROPN
admet-2684	405	6	fang	fang	PROPN
admet-2684	405	7	,	,	PUNCT
admet-2684	405	8	l.	l.	PROPN
admet-2684	405	9	ravindar	ravindar	PROPN
admet-2684	405	10	,	,	PUNCT
admet-2684	405	11	k.p	k.p	PROPN
admet-2684	405	12	.	.	PROPN
admet-2684	405	13	rakesh	rakesh	PROPN
admet-2684	405	14	,	,	PUNCT
admet-2684	405	15	h.m	h.m	PROPN
admet-2684	405	16	.	.	PROPN
admet-2684	405	17	manukumar	manukumar	PROPN
admet-2684	405	18	,	,	PUNCT
admet-2684	405	19	c.s	c.s	PROPN
admet-2684	405	20	.	.	PROPN
admet-2684	405	21	shantharam	shantharam	PROPN
admet-2684	405	22	,	,	PUNCT
admet-2684	405	23	n.s	n.s	PROPN
admet-2684	405	24	.	.	PROPN
admet-2684	405	25	alharbi	alharbi	PROPN
admet-2684	405	26	,	,	PUNCT
admet-2684	405	27	h.l	h.l	PROPN
admet-2684	405	28	.	.	PROPN
admet-2684	405	29	qin	qin	PROPN
admet-2684	405	30	.	.	PUNCT
admet-2684	406	1	synthetic	synthetic	ADJ
admet-2684	406	2	approaches	approach	NOUN
admet-2684	406	3	and	and	CCONJ
admet-2684	406	4	pharmaceutical	pharmaceutical	NOUN
admet-2684	406	5	applications	application	NOUN
admet-2684	406	6	of	of	ADP
admet-2684	406	7	chloro	chloro	NOUN
admet-2684	406	8	-	-	PUNCT
admet-2684	406	9	containing	contain	VERB
admet-2684	406	10	molecules	molecule	NOUN
admet-2684	406	11	for	for	ADP
admet-2684	406	12	drug	drug	NOUN
admet-2684	406	13	discovery	discovery	NOUN
admet-2684	406	14	:	:	PUNCT
admet-2684	406	15	a	a	DET
admet-2684	406	16	critical	critical	ADJ
admet-2684	406	17	review	review	NOUN
admet-2684	406	18	.	.	PUNCT
admet-2684	407	1	european	european	PROPN
admet-2684	407	2	journal	journal	PROPN
admet-2684	407	3	of	of	ADP
admet-2684	407	4	medicinal	medicinal	ADJ
admet-2684	407	5	chemistry	chemistry	NOUN
admet-2684	407	6	173	173	NUM
admet-2684	407	7	(	(	PUNCT
admet-2684	407	8	2019	2019	NUM
admet-2684	407	9	)	)	PUNCT
admet-2684	407	10	117	117	NUM
admet-2684	407	11	-	-	SYM
admet-2684	407	12	153	153	NUM
admet-2684	407	13	.	.	PUNCT
admet-2684	408	1	https://doi.org/10.1016/j.ejmech.2019.03.063	https://doi.org/10.1016/j.ejmech.2019.03.063	PROPN
admet-2684	408	2	[	[	X
admet-2684	408	3	46	46	NUM
admet-2684	408	4	]	]	PUNCT
admet-2684	408	5	m.	m.	NOUN
admet-2684	408	6	dolezal	dolezal	PROPN
admet-2684	408	7	,	,	PUNCT
admet-2684	408	8	j.	j.	PROPN
admet-2684	408	9	zitko	zitko	PROPN
admet-2684	408	10	,	,	PUNCT
admet-2684	408	11	z.	z.	PROPN
admet-2684	408	12	osicka	osicka	PROPN
admet-2684	408	13	,	,	PUNCT
admet-2684	408	14	j.	j.	PROPN
admet-2684	408	15	kunes	kunes	PROPN
admet-2684	408	16	,	,	PUNCT
admet-2684	408	17	m.	m.	NOUN
admet-2684	408	18	vejsova	vejsova	PROPN
admet-2684	408	19	,	,	PUNCT
admet-2684	408	20	v.	v.	ADP
admet-2684	408	21	buchta	buchta	PROPN
admet-2684	408	22	,	,	PUNCT
admet-2684	408	23	j.	j.	PROPN
admet-2684	408	24	dohnal	dohnal	PROPN
admet-2684	408	25	,	,	PUNCT
admet-2684	408	26	j.	j.	PROPN
admet-2684	408	27	jampilek	jampilek	PROPN
admet-2684	408	28	,	,	PUNCT
admet-2684	408	29	k.	k.	PROPN
admet-2684	408	30	kralova	kralova	PROPN
admet-2684	408	31	.	.	PUNCT
admet-2684	409	1	synthesis	synthesis	NOUN
admet-2684	409	2	,	,	PUNCT
admet-2684	409	3	antimycobacterial	antimycobacterial	ADJ
admet-2684	409	4	,	,	PUNCT
admet-2684	409	5	antifungal	antifungal	ADJ
admet-2684	409	6	and	and	CCONJ
admet-2684	409	7	photosynthesis	photosynthesis	NOUN
admet-2684	409	8	-	-	PUNCT
admet-2684	409	9	inhibiting	inhibit	VERB
admet-2684	409	10	activity	activity	NOUN
admet-2684	409	11	of	of	ADP
admet-2684	409	12	chlorinated	chlorinate	VERB
admet-2684	409	13	nphenylpyrazine-2	nphenylpyrazine-2	NOUN
admet-2684	409	14	-	-	PUNCT
admet-2684	409	15	carboxamides	carboxamide	NOUN
admet-2684	409	16	.	.	PUNCT
admet-2684	410	1	molecules	molecule	NOUN
admet-2684	410	2	15	15	NUM
admet-2684	410	3	(	(	PUNCT
admet-2684	410	4	2010	2010	NUM
admet-2684	410	5	)	)	PUNCT
admet-2684	410	6	8567	8567	NUM
admet-2684	410	7	-	-	SYM
admet-2684	410	8	8581	8581	NUM
admet-2684	410	9	.	.	PUNCT
admet-2684	411	1	https://doi.org/10.3390/molecules15128567	https://doi.org/10.3390/molecules15128567	NOUN
admet-2684	412	1	[	[	X
admet-2684	412	2	47	47	NUM
admet-2684	412	3	]	]	X
admet-2684	412	4	o.s	o.s	PROPN
admet-2684	412	5	.	.	PROPN
admet-2684	412	6	faleye	faleye	PROPN
admet-2684	412	7	,	,	PUNCT
admet-2684	412	8	b.r	b.r	PROPN
admet-2684	412	9	.	.	PROPN
admet-2684	412	10	boya	boya	PROPN
admet-2684	412	11	,	,	PUNCT
admet-2684	412	12	j.h	j.h	PROPN
admet-2684	412	13	.	.	PROPN
admet-2684	412	14	lee	lee	PROPN
admet-2684	412	15	,	,	PUNCT
admet-2684	412	16	i.	i.	PROPN
admet-2684	412	17	choi	choi	PROPN
admet-2684	412	18	,	,	PUNCT
admet-2684	412	19	j.	j.	PROPN
admet-2684	412	20	lee	lee	PROPN
admet-2684	412	21	.	.	PROPN
admet-2684	413	1	halogenated	halogenated	ADJ
admet-2684	413	2	antimicrobial	antimicrobial	ADJ
admet-2684	413	3	agents	agent	NOUN
admet-2684	413	4	to	to	PART
admet-2684	413	5	combat	combat	VERB
admet-2684	413	6	drugresistant	drugresistant	NOUN
admet-2684	413	7	pathogens	pathogen	NOUN
admet-2684	413	8	.	.	PUNCT
admet-2684	414	1	pharmacological	pharmacological	ADJ
admet-2684	414	2	reviews	review	NOUN
admet-2684	414	3	76	76	NUM
admet-2684	414	4	(	(	PUNCT
admet-2684	414	5	2023	2023	NUM
admet-2684	414	6	)	)	PUNCT
admet-2684	414	7	90	90	NUM
admet-2684	414	8	-	-	SYM
admet-2684	414	9	141	141	NUM
admet-2684	414	10	.	.	PUNCT
admet-2684	415	1	https://doi.org/10.1124/pharmrev.123.000863	https://doi.org/10.1124/pharmrev.123.000863	PROPN
admet-2684	415	2	[	[	X
admet-2684	415	3	48	48	NUM
admet-2684	415	4	]	]	PUNCT
admet-2684	415	5	r.	r.	PROPN
admet-2684	415	6	huber	huber	PROPN
admet-2684	415	7	,	,	PUNCT
admet-2684	415	8	l.	l.	PROPN
admet-2684	415	9	marcourt	marcourt	PROPN
admet-2684	415	10	,	,	PUNCT
admet-2684	415	11	m.	m.	NOUN
admet-2684	415	12	heritier	heritier	NOUN
admet-2684	415	13	,	,	PUNCT
admet-2684	415	14	a.	a.	NOUN
admet-2684	415	15	luscher	luscher	PROPN
admet-2684	415	16	,	,	PUNCT
admet-2684	415	17	l.	l.	PROPN
admet-2684	415	18	guebey	guebey	PROPN
admet-2684	415	19	,	,	PUNCT
admet-2684	415	20	s.	s.	PROPN
admet-2684	415	21	schnee	schnee	PROPN
admet-2684	415	22	,	,	PUNCT
admet-2684	415	23	e.	e.	PROPN
admet-2684	415	24	michellod	michellod	PROPN
admet-2684	415	25	,	,	PUNCT
admet-2684	415	26	s.	s.	PROPN
admet-2684	415	27	guerrier	guerrier	PROPN
admet-2684	415	28	,	,	PUNCT
admet-2684	415	29	j.l	j.l	PROPN
admet-2684	415	30	.	.	PROPN
admet-2684	415	31	wolfender	wolfender	PROPN
admet-2684	415	32	,	,	PUNCT
admet-2684	415	33	l.	l.	PROPN
admet-2684	415	34	scapozza	scapozza	PROPN
admet-2684	415	35	,	,	PUNCT
admet-2684	415	36	t.	t.	NOUN
admet-2684	415	37	kohler	kohler	PROPN
admet-2684	415	38	,	,	PUNCT
admet-2684	415	39	k.	k.	PROPN
admet-2684	415	40	gindro	gindro	PROPN
admet-2684	415	41	,	,	PUNCT
admet-2684	415	42	e.f	e.f	PROPN
admet-2684	415	43	.	.	NOUN
admet-2684	415	44	queiroz.generation	queiroz.generation	NOUN
admet-2684	415	45	of	of	ADP
admet-2684	415	46	potent	potent	ADJ
admet-2684	415	47	antibacterial	antibacterial	ADJ
admet-2684	415	48	compounds	compound	NOUN
admet-2684	415	49	through	through	ADP
admet-2684	415	50	enzymatic	enzymatic	ADJ
admet-2684	415	51	and	and	CCONJ
admet-2684	415	52	chemical	chemical	ADJ
admet-2684	415	53	modifications	modification	NOUN
admet-2684	415	54	of	of	ADP
admet-2684	415	55	the	the	DET
admet-2684	415	56	trans	trans	PROPN
admet-2684	415	57	-	-	PROPN
admet-2684	415	58	δ	δ	NOUN
admet-2684	415	59	-	-	PUNCT
admet-2684	415	60	viniferin	viniferin	NOUN
admet-2684	415	61	scaffold	scaffold	NOUN
admet-2684	415	62	.	.	PUNCT
admet-2684	416	1	scientific	scientific	ADJ
admet-2684	416	2	reports	report	NOUN
admet-2684	416	3	13	13	NUM
admet-2684	416	4	(	(	PUNCT
admet-2684	416	5	2023	2023	NUM
admet-2684	416	6	)	)	PUNCT
admet-2684	416	7	15986	15986	NUM
admet-2684	416	8	.	.	PUNCT
admet-2684	416	9	https://doi.org/10.1038/s41598-023-43000-5	https://doi.org/10.1038/s41598-023-43000-5	X
admet-2684	417	1	[	[	X
admet-2684	417	2	49	49	NUM
admet-2684	417	3	]	]	PUNCT
admet-2684	417	4	a.	a.	PROPN
admet-2684	417	5	krawczyk	krawczyk	PROPN
admet-2684	417	6	-	-	PUNCT
admet-2684	417	7	lebek	lebek	PROPN
admet-2684	417	8	,	,	PUNCT
admet-2684	417	9	b.	b.	PROPN
admet-2684	417	10	zarowska	zarowska	PROPN
admet-2684	417	11	,	,	PUNCT
admet-2684	417	12	t.	t.	PROPN
admet-2684	417	13	janeczko	janeczko	PROPN
admet-2684	417	14	,	,	PUNCT
admet-2684	417	15	e.	e.	PROPN
admet-2684	417	16	kostrzewa	kostrzewa	PROPN
admet-2684	417	17	-	-	PUNCT
admet-2684	417	18	suslow	suslow	ADJ
admet-2684	417	19	.	.	PUNCT
admet-2684	418	1	antimicrobial	antimicrobial	ADJ
admet-2684	418	2	activity	activity	NOUN
admet-2684	418	3	of	of	ADP
admet-2684	418	4	chalcones	chalcone	NOUN
admet-2684	418	5	with	with	ADP
admet-2684	418	6	a	a	DET
admet-2684	418	7	chlorine	chlorine	NOUN
admet-2684	418	8	atom	atom	NOUN
admet-2684	418	9	and	and	CCONJ
admet-2684	418	10	their	their	PRON
admet-2684	418	11	glycosides	glycoside	NOUN
admet-2684	418	12	.	.	PUNCT
admet-2684	419	1	international	international	ADJ
admet-2684	419	2	journal	journal	NOUN
admet-2684	419	3	of	of	ADP
admet-2684	419	4	molecular	molecular	ADJ
admet-2684	419	5	sciences	science	NOUN
admet-2684	419	6	25	25	NUM
admet-2684	419	7	(	(	PUNCT
admet-2684	419	8	2024	2024	NUM
admet-2684	419	9	)	)	PUNCT
admet-2684	419	10	9718	9718	NUM
admet-2684	419	11	.	.	PUNCT
admet-2684	420	1	https://doi.org/10.3390/ijms25179718	https://doi.org/10.3390/ijms25179718	PROPN
admet-2684	420	2	[	[	X
admet-2684	420	3	50	50	NUM
admet-2684	420	4	]	]	PUNCT
admet-2684	420	5	m.	m.	NOUN
admet-2684	420	6	perz	perz	PROPN
admet-2684	420	7	,	,	PUNCT
admet-2684	420	8	d.	d.	PROPN
admet-2684	420	9	szymanowska	szymanowska	PROPN
admet-2684	420	10	,	,	PUNCT
admet-2684	420	11	t.	t.	PROPN
admet-2684	420	12	janeczko	janeczko	PROPN
admet-2684	420	13	,	,	PUNCT
admet-2684	420	14	e.	e.	PROPN
admet-2684	420	15	kostrzewa	kostrzewa	PROPN
admet-2684	420	16	-	-	PUNCT
admet-2684	420	17	suslow	suslow	ADJ
admet-2684	420	18	.	.	PUNCT
admet-2684	421	1	antimicrobial	antimicrobial	ADJ
admet-2684	421	2	properties	property	NOUN
admet-2684	421	3	of	of	ADP
admet-2684	421	4	flavonoid	flavonoid	NOUN
admet-2684	421	5	derivatives	derivative	NOUN
admet-2684	421	6	with	with	ADP
admet-2684	421	7	bromine	bromine	NOUN
admet-2684	421	8	,	,	PUNCT
admet-2684	421	9	chlorine	chlorine	NOUN
admet-2684	421	10	,	,	PUNCT
admet-2684	421	11	and	and	CCONJ
admet-2684	421	12	nitro	nitro	NOUN
admet-2684	421	13	group	group	NOUN
admet-2684	421	14	obtained	obtain	VERB
admet-2684	421	15	by	by	ADP
admet-2684	421	16	chemical	chemical	ADJ
admet-2684	421	17	synthesis	synthesis	NOUN
admet-2684	421	18	and	and	CCONJ
admet-2684	421	19	biotransformation	biotransformation	NOUN
admet-2684	421	20	studies	study	NOUN
admet-2684	421	21	.	.	PUNCT
admet-2684	422	1	international	international	ADJ
admet-2684	422	2	journal	journal	NOUN
admet-2684	422	3	of	of	ADP
admet-2684	422	4	molecular	molecular	ADJ
admet-2684	422	5	sciences	science	NOUN
admet-2684	422	6	25	25	NUM
admet-2684	422	7	(	(	PUNCT
admet-2684	422	8	2024	2024	NUM
admet-2684	422	9	)	)	PUNCT
admet-2684	422	10	5540	5540	NUM
admet-2684	422	11	.	.	PUNCT
admet-2684	423	1	https://doi.org/10.3390/ijms25105540	https://doi.org/10.3390/ijms25105540	PROPN
admet-2684	424	1	[	[	X
admet-2684	424	2	51	51	NUM
admet-2684	424	3	]	]	X
admet-2684	424	4	t.a	t.a	PROPN
admet-2684	424	5	.	.	PROPN
admet-2684	424	6	taylor	taylor	PROPN
admet-2684	424	7	,	,	PUNCT
admet-2684	424	8	c.g	c.g	PROPN
admet-2684	424	9	.	.	PROPN
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admet-2684	424	11	.	.	PUNCT
admet-2684	424	12	staphylococcus	staphylococcus	NOUN
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admet-2684	424	14	infection	infection	NOUN
admet-2684	424	15	;	;	PUNCT
admet-2684	424	16	statpearls	statpearl	NOUN
admet-2684	424	17	publishing	publishing	NOUN
admet-2684	424	18	,	,	PUNCT
admet-2684	424	19	treasure	treasure	NOUN
admet-2684	424	20	island	island	NOUN
admet-2684	424	21	,	,	PUNCT
admet-2684	424	22	fl	fl	PROPN
admet-2684	424	23	,	,	PUNCT
admet-2684	424	24	usa	usa	PROPN
admet-2684	424	25	,	,	PUNCT
admet-2684	424	26	2024	2024	NUM
admet-2684	424	27	.	.	PUNCT
admet-2684	424	28	https://www.ncbi.nlm.nih.gov/books/nbk441868	https://www.ncbi.nlm.nih.gov/books/nbk441868	PROPN
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admet-2684	424	30	accessed	access	VERB
admet-2684	424	31	on	on	ADP
admet-2684	424	32	10	10	NUM
admet-2684	424	33	february	february	NOUN
admet-2684	424	34	2025	2025	NUM
admet-2684	424	35	)	)	PUNCT
admet-2684	424	36	.	.	PUNCT
admet-2684	425	1	https://doi.org/10.5599/admet.2684	https://doi.org/10.5599/admet.2684	NOUN
admet-2684	426	1	https://doi.org/10.1016/j.bmc.2012.10.056	https://doi.org/10.1016/j.bmc.2012.10.056	PROPN
admet-2684	427	1	https://doi.org/10.1021/jm9803572	https://doi.org/10.1021/jm9803572	PRON
admet-2684	428	1	https://doi.org/10.1054/tuld.2000.0240	https://doi.org/10.1054/tuld.2000.0240	PROPN
admet-2684	428	2	https://doi.org/10.1016/j.chembiol.2012.01.001	https://doi.org/10.1016/j.chembiol.2012.01.001	PROPN
admet-2684	428	3	https://doi.org/10.1002/ijch.202200076	https://doi.org/10.1002/ijch.202200076	PROPN
admet-2684	428	4	https://doi.org/10.1016/j.tibtech.2018.06.008	https://doi.org/10.1016/j.tibtech.2018.06.008	PROPN
admet-2684	428	5	https://doi.org/10.1126/scitranslmed.aaf7951	https://doi.org/10.1126/scitranslmed.aaf7951	PROPN
admet-2684	428	6	https://doi.org/10.1002/pmic.201600212	https://doi.org/10.1002/pmic.201600212	NOUN
admet-2684	428	7	https://doi.org/10.3389/fphar.2018.00353	https://doi.org/10.3389/fphar.2018.00353	PROPN
admet-2684	428	8	https://doi.org/10.1002/(sici)1526-4998(200001)56:1%3c3::aid-ps107%3e3.0.co;2-p	https://doi.org/10.1002/(sici)1526-4998(200001)56:1%3c3::aid-ps107%3e3.0.co;2-p	PROPN
admet-2684	428	9	https://doi.org/10.1002/(sici)1526-4998(200001)56:1%3c3::aid-ps107%3e3.0.co;2-p	https://doi.org/10.1002/(sici)1526-4998(200001)56:1%3c3::aid-ps107%3e3.0.co;2-p	PROPN
admet-2684	428	10	https://doi.org/10.1016/j.ejmech.2019.03.063	https://doi.org/10.1016/j.ejmech.2019.03.063	ADJ
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admet-2684	428	12	https://doi.org/10.1124/pharmrev.123.000863	https://doi.org/10.1124/pharmrev.123.000863	PROPN
admet-2684	428	13	https://doi.org/10.1038/s41598-023-43000-5	https://doi.org/10.1038/s41598-023-43000-5	NUM
admet-2684	428	14	https://doi.org/10.3390/ijms25179718	https://doi.org/10.3390/ijms25179718	PROPN
admet-2684	428	15	https://doi.org/10.3390/ijms25105540	https://doi.org/10.3390/ijms25105540	PROPN
admet-2684	428	16	https://www.ncbi.nlm.nih.gov/books/nbk441868	https://www.ncbi.nlm.nih.gov/books/nbk441868	PROPN
admet-2684	428	17	l.	l.	PROPN
admet-2684	428	18	vrablova	vrablova	PROPN
admet-2684	428	19	et	et	PROPN
admet-2684	428	20	al	al	PROPN
admet-2684	428	21	.	.	PROPN
admet-2684	428	22	admet	admet	PROPN
admet-2684	428	23	&	&	CCONJ
admet-2684	428	24	dmpk	dmpk	PROPN
admet-2684	428	25	13(2	13(2	PROPN
admet-2684	428	26	)	)	PUNCT
admet-2684	428	27	(	(	PUNCT
admet-2684	428	28	2025	2025	NUM
admet-2684	428	29	)	)	PUNCT
admet-2684	428	30	2684	2684	NUM
admet-2684	428	31	16	16	NUM
admet-2684	429	1	[	[	X
admet-2684	429	2	52	52	NUM
admet-2684	429	3	]	]	PUNCT
admet-2684	429	4	t.	t.	PROPN
admet-2684	429	5	gonec	gonec	PROPN
admet-2684	429	6	,	,	PUNCT
admet-2684	429	7	j.	j.	PROPN
admet-2684	429	8	kos	kos	PROPN
admet-2684	429	9	,	,	PUNCT
admet-2684	429	10	m.	m.	NOUN
admet-2684	429	11	pesko	pesko	ADV
admet-2684	429	12	,	,	PUNCT
admet-2684	429	13	j.	j.	PROPN
admet-2684	429	14	dohanosova	dohanosova	PROPN
admet-2684	429	15	,	,	PUNCT
admet-2684	429	16	m.	m.	NOUN
admet-2684	429	17	oravec	oravec	PROPN
admet-2684	429	18	,	,	PUNCT
admet-2684	429	19	t.	t.	PROPN
admet-2684	429	20	liptaj	liptaj	PROPN
admet-2684	429	21	,	,	PUNCT
admet-2684	429	22	k.	k.	PROPN
admet-2684	429	23	kralova	kralova	PROPN
admet-2684	429	24	,	,	PUNCT
admet-2684	429	25	j.	j.	PROPN
admet-2684	429	26	jampilek	jampilek	PROPN
admet-2684	429	27	.	.	PUNCT
admet-2684	430	1	halogenated	halogenated	ADJ
admet-2684	430	2	1hydroxynaphthalene-2	1hydroxynaphthalene-2	NUM
admet-2684	430	3	-	-	PUNCT
admet-2684	430	4	carboxanilides	carboxanilide	NOUN
admet-2684	430	5	affecting	affect	VERB
admet-2684	430	6	photosynthetic	photosynthetic	ADJ
admet-2684	430	7	electron	electron	NOUN
admet-2684	430	8	transport	transport	NOUN
admet-2684	430	9	in	in	ADP
admet-2684	430	10	photosystem	photosystem	PROPN
admet-2684	430	11	ii	ii	PROPN
admet-2684	430	12	.	.	PUNCT
admet-2684	430	13	molecules	molecule	NOUN
admet-2684	430	14	22	22	NUM
admet-2684	430	15	(	(	PUNCT
admet-2684	430	16	2017	2017	NUM
admet-2684	430	17	)	)	PUNCT
admet-2684	430	18	1709	1709	NUM
admet-2684	430	19	.	.	PUNCT
admet-2684	431	1	https://doi.org/10.3390/molecules22101709	https://doi.org/10.3390/molecules22101709	NOUN
admet-2684	432	1	[	[	X
admet-2684	432	2	53	53	NUM
admet-2684	432	3	]	]	PUNCT
admet-2684	432	4	ezchrom	ezchrom	ADP
admet-2684	432	5	elite	elite	ADJ
admet-2684	432	6	software	software	PROPN
admet-2684	432	7	ver	ver	NOUN
admet-2684	432	8	.	.	PUNCT
admet-2684	433	1	3.3.2	3.3.2	NUM
admet-2684	433	2	.	.	X
admet-2684	434	1	agilent	agilent	PROPN
admet-2684	434	2	,	,	PUNCT
admet-2684	434	3	santa	santa	PROPN
admet-2684	434	4	clara	clara	PROPN
admet-2684	434	5	,	,	PUNCT
admet-2684	434	6	ca	ca	PROPN
admet-2684	434	7	,	,	PUNCT
admet-2684	434	8	usa	usa	PROPN
admet-2684	434	9	.	.	PROPN
admet-2684	434	10	https://ezchromelite.software.informer.com/3.3/	https://ezchromelite.software.informer.com/3.3/	PROPN
admet-2684	435	1	[	[	X
admet-2684	435	2	54	54	NUM
admet-2684	435	3	]	]	PUNCT
admet-2684	435	4	i.	i.	PROPN
admet-2684	435	5	zadrazilova	zadrazilova	PROPN
admet-2684	435	6	,	,	PUNCT
admet-2684	435	7	s.	s.	PROPN
admet-2684	435	8	pospisilova	pospisilova	PROPN
admet-2684	435	9	,	,	PUNCT
admet-2684	435	10	k.	k.	PROPN
admet-2684	435	11	pauk	pauk	PROPN
admet-2684	435	12	,	,	PUNCT
admet-2684	435	13	a.	a.	NOUN
admet-2684	435	14	imramovsky	imramovsky	PROPN
admet-2684	435	15	,	,	PUNCT
admet-2684	435	16	j.	j.	PROPN
admet-2684	435	17	vinsova	vinsova	PROPN
admet-2684	435	18	,	,	PUNCT
admet-2684	435	19	a.	a.	NOUN
admet-2684	435	20	cizek	cizek	PROPN
admet-2684	435	21	,	,	PUNCT
admet-2684	435	22	j.	j.	PROPN
admet-2684	435	23	jampilek	jampilek	PROPN
admet-2684	435	24	.	.	PUNCT
admet-2684	436	1	in	in	ADP
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admet-2684	436	8	-	-	PUNCT
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admet-2684	436	14	-	-	PUNCT
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admet-2684	436	16	-	-	PUNCT
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admet-2684	436	25	(	(	PUNCT
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admet-2684	436	27	)	)	PUNCT
admet-2684	436	28	349534	349534	NUM
admet-2684	436	29	.	.	PUNCT
admet-2684	437	1	https://doi.org/10.1155/2015/349534	https://doi.org/10.1155/2015/349534	PROPN
admet-2684	438	1	[	[	X
admet-2684	438	2	55	55	NUM
admet-2684	438	3	]	]	X
admet-2684	438	4	u.	u.	NOUN
admet-2684	438	5	nubel	nubel	PROPN
admet-2684	438	6	,	,	PUNCT
admet-2684	438	7	j.	j.	PROPN
admet-2684	438	8	dordel	dordel	PROPN
admet-2684	438	9	,	,	PUNCT
admet-2684	438	10	k.	k.	PROPN
admet-2684	438	11	kurt	kurt	PROPN
admet-2684	438	12	,	,	PUNCT
admet-2684	438	13	b.	b.	PROPN
admet-2684	438	14	strommenger	strommenger	PROPN
admet-2684	438	15	,	,	PUNCT
admet-2684	438	16	h.	h.	PROPN
admet-2684	438	17	westh	westh	PROPN
admet-2684	438	18	,	,	PUNCT
admet-2684	438	19	s.k	s.k	PROPN
admet-2684	438	20	.	.	PROPN
admet-2684	438	21	shukla	shukla	PROPN
admet-2684	438	22	,	,	PUNCT
admet-2684	438	23	h.	h.	PROPN
admet-2684	438	24	zemlickova	zemlickova	PROPN
admet-2684	438	25	,	,	PUNCT
admet-2684	438	26	r.	r.	PROPN
admet-2684	438	27	leblois	leblois	PROPN
admet-2684	438	28	,	,	PUNCT
admet-2684	438	29	t.	t.	PROPN
admet-2684	438	30	wirth	wirth	PROPN
admet-2684	438	31	,	,	PUNCT
admet-2684	438	32	t.	t.	PROPN
admet-2684	438	33	jombart	jombart	PROPN
admet-2684	438	34	,	,	PUNCT
admet-2684	438	35	f.	f.	PROPN
admet-2684	438	36	balloux	balloux	PROPN
admet-2684	438	37	,	,	PUNCT
admet-2684	438	38	w.	w.	PROPN
admet-2684	438	39	witte	witte	PROPN
admet-2684	438	40	.	.	PUNCT
admet-2684	439	1	a	a	DET
admet-2684	439	2	timescale	timescale	NOUN
admet-2684	439	3	for	for	ADP
admet-2684	439	4	evolution	evolution	NOUN
admet-2684	439	5	,	,	PUNCT
admet-2684	439	6	population	population	NOUN
admet-2684	439	7	expansion	expansion	NOUN
admet-2684	439	8	,	,	PUNCT
admet-2684	439	9	and	and	CCONJ
admet-2684	439	10	spatial	spatial	ADJ
admet-2684	439	11	spread	spread	NOUN
admet-2684	439	12	of	of	ADP
admet-2684	439	13	an	an	DET
admet-2684	439	14	emerging	emerge	VERB
admet-2684	439	15	clone	clone	NOUN
admet-2684	439	16	of	of	ADP
admet-2684	439	17	methicillin	methicillin	NOUN
admet-2684	439	18	-	-	PUNCT
admet-2684	439	19	resistant	resistant	ADJ
admet-2684	439	20	staphylococcus	staphylococcus	NOUN
admet-2684	439	21	aureus	aureus	NOUN
admet-2684	439	22	.	.	PUNCT
admet-2684	440	1	plos	plos	PROPN
admet-2684	440	2	pathogens	pathogen	NOUN
admet-2684	440	3	6	6	NUM
admet-2684	440	4	(	(	PUNCT
admet-2684	440	5	2010	2010	NUM
admet-2684	440	6	)	)	PUNCT
admet-2684	440	7	e1000855	e1000855	PROPN
admet-2684	440	8	.	.	PUNCT
admet-2684	441	1	https://doi.org/10.1371/journal.ppat.1000855	https://doi.org/10.1371/journal.ppat.1000855	PROPN
admet-2684	442	1	[	[	X
admet-2684	442	2	56	56	NUM
admet-2684	442	3	]	]	X
admet-2684	442	4	g.	g.	PROPN
admet-2684	442	5	bosgelmez	bosgelmez	PROPN
admet-2684	442	6	-	-	PUNCT
admet-2684	442	7	tinaz	tinaz	PROPN
admet-2684	442	8	,	,	PUNCT
admet-2684	442	9	s.	s.	PROPN
admet-2684	442	10	ulusoy	ulusoy	PROPN
admet-2684	442	11	,	,	PUNCT
admet-2684	442	12	b.	b.	PROPN
admet-2684	442	13	aridogan	aridogan	PROPN
admet-2684	442	14	,	,	PUNCT
admet-2684	442	15	f.	f.	PROPN
admet-2684	442	16	coskun	coskun	PROPN
admet-2684	442	17	-	-	PUNCT
admet-2684	442	18	ari	ari	PROPN
admet-2684	442	19	.	.	PUNCT
admet-2684	442	20	evaluation	evaluation	NOUN
admet-2684	442	21	of	of	ADP
admet-2684	442	22	different	different	ADJ
admet-2684	442	23	methods	method	NOUN
admet-2684	442	24	to	to	PART
admet-2684	442	25	detect	detect	VERB
admet-2684	442	26	oxacillin	oxacillin	ADJ
admet-2684	442	27	resistance	resistance	NOUN
admet-2684	442	28	in	in	ADP
admet-2684	442	29	staphylococcus	staphylococcus	NOUN
admet-2684	442	30	aureus	aureus	NOUN
admet-2684	442	31	and	and	CCONJ
admet-2684	442	32	their	their	PRON
admet-2684	442	33	clinical	clinical	ADJ
admet-2684	442	34	laboratory	laboratory	NOUN
admet-2684	442	35	utility	utility	NOUN
admet-2684	442	36	.	.	PUNCT
admet-2684	443	1	european	european	ADJ
admet-2684	443	2	journal	journal	PROPN
admet-2684	443	3	of	of	ADP
admet-2684	443	4	clinical	clinical	ADJ
admet-2684	443	5	microbiology	microbiology	NOUN
admet-2684	443	6	&	&	CCONJ
admet-2684	443	7	infectious	infectious	ADJ
admet-2684	443	8	diseases	disease	NOUN
admet-2684	443	9	25	25	NUM
admet-2684	443	10	(	(	PUNCT
admet-2684	443	11	2006	2006	NUM
admet-2684	443	12	)	)	PUNCT
admet-2684	443	13	410	410	NUM
admet-2684	443	14	-	-	SYM
admet-2684	443	15	412	412	NUM
admet-2684	443	16	.	.	PUNCT
admet-2684	444	1	https://doi.org/10.1007/s10096-0060153-8	https://doi.org/10.1007/s10096-0060153-8	NOUN
admet-2684	444	2	[	[	X
admet-2684	444	3	57	57	NUM
admet-2684	444	4	]	]	PUNCT
admet-2684	444	5	f.	f.	PROPN
admet-2684	444	6	martineau	martineau	PROPN
admet-2684	444	7	,	,	PUNCT
admet-2684	444	8	f.j	f.j	PROPN
admet-2684	444	9	.	.	PROPN
admet-2684	444	10	picard	picard	PROPN
admet-2684	444	11	,	,	PUNCT
admet-2684	444	12	p.h	p.h	PROPN
admet-2684	444	13	.	.	PROPN
admet-2684	444	14	roy	roy	PROPN
admet-2684	444	15	,	,	PUNCT
admet-2684	444	16	m.	m.	NOUN
admet-2684	444	17	ouellette	ouellette	PROPN
admet-2684	444	18	,	,	PUNCT
admet-2684	444	19	m.g	m.g	PROPN
admet-2684	444	20	.	.	PROPN
admet-2684	444	21	bergeron	bergeron	PROPN
admet-2684	444	22	.	.	PUNCT
admet-2684	445	1	species	species	NOUN
admet-2684	445	2	-	-	PUNCT
admet-2684	445	3	specific	specific	ADJ
admet-2684	445	4	and	and	CCONJ
admet-2684	445	5	ubiquitousdna	ubiquitousdna	ADV
admet-2684	445	6	-	-	PUNCT
admet-2684	445	7	based	base	VERB
admet-2684	445	8	assays	assay	NOUN
admet-2684	445	9	for	for	ADP
admet-2684	445	10	rapid	rapid	ADJ
admet-2684	445	11	identification	identification	NOUN
admet-2684	445	12	of	of	ADP
admet-2684	445	13	staphylococcus	staphylococcus	NOUN
admet-2684	445	14	aureus	aureus	NOUN
admet-2684	445	15	.	.	PUNCT
admet-2684	446	1	journal	journal	PROPN
admet-2684	446	2	of	of	ADP
admet-2684	446	3	clinical	clinical	ADJ
admet-2684	446	4	microbiology	microbiology	NOUN
admet-2684	446	5	36	36	NUM
admet-2684	446	6	(	(	PUNCT
admet-2684	446	7	1998	1998	NUM
admet-2684	446	8	)	)	PUNCT
admet-2684	446	9	618	618	NUM
admet-2684	446	10	-	-	SYM
admet-2684	446	11	623	623	NUM
admet-2684	446	12	.	.	PUNCT
admet-2684	447	1	https://doi.org/10.1128/jcm.36.3.618-623.1998	https://doi.org/10.1128/jcm.36.3.618-623.1998	PRON
admet-2684	448	1	[	[	X
admet-2684	448	2	58	58	NUM
admet-2684	448	3	]	]	X
admet-2684	448	4	m.p	m.p	PROPN
admet-2684	448	5	.	.	PROPN
admet-2684	448	6	weinstein	weinstein	PROPN
admet-2684	448	7	,	,	PUNCT
admet-2684	448	8	j.b	j.b	PROPN
admet-2684	448	9	.	.	PROPN
admet-2684	448	10	patel	patel	PROPN
admet-2684	448	11	.	.	PUNCT
admet-2684	449	1	methods	method	NOUN
admet-2684	449	2	for	for	ADP
admet-2684	449	3	dilution	dilution	NOUN
admet-2684	449	4	antimicrobial	antimicrobial	ADJ
admet-2684	449	5	susceptibility	susceptibility	NOUN
admet-2684	449	6	tests	test	VERB
admet-2684	449	7	for	for	ADP
admet-2684	449	8	bacteria	bacteria	NOUN
admet-2684	449	9	that	that	PRON
admet-2684	449	10	grow	grow	VERB
admet-2684	449	11	aerobically	aerobically	ADV
admet-2684	449	12	:	:	PUNCT
admet-2684	449	13	m07	m07	NUM
admet-2684	449	14	-	-	PUNCT
admet-2684	449	15	a11	a11	PROPN
admet-2684	449	16	,	,	PUNCT
admet-2684	449	17	11th	11th	ADJ
admet-2684	449	18	edition	edition	NOUN
admet-2684	449	19	,	,	PUNCT
admet-2684	449	20	committee	committee	NOUN
admet-2684	449	21	for	for	ADP
admet-2684	449	22	clinical	clinical	ADJ
admet-2684	449	23	laboratory	laboratory	NOUN
admet-2684	449	24	standards	standard	NOUN
admet-2684	449	25	,	,	PUNCT
admet-2684	449	26	wayne	wayne	PROPN
admet-2684	449	27	,	,	PUNCT
admet-2684	449	28	pa	pa	PROPN
admet-2684	449	29	,	,	PUNCT
admet-2684	449	30	2018	2018	NUM
admet-2684	449	31	.	.	PUNCT
admet-2684	450	1	https://clsi.org/media/1928/m07ed11_sample.pdf	https://clsi.org/media/1928/m07ed11_sample.pdf	ADJ
admet-2684	450	2	[	[	X
admet-2684	450	3	59	59	NUM
admet-2684	450	4	]	]	PUNCT
admet-2684	450	5	r.	r.	PROPN
admet-2684	450	6	schwalbe	schwalbe	PROPN
admet-2684	450	7	,	,	PUNCT
admet-2684	450	8	l.	l.	PROPN
admet-2684	450	9	steele	steele	PROPN
admet-2684	450	10	-	-	PUNCT
admet-2684	450	11	moore	moore	PROPN
admet-2684	450	12	,	,	PUNCT
admet-2684	450	13	a.c	a.c	PROPN
admet-2684	450	14	.	.	PROPN
admet-2684	450	15	goodwin	goodwin	PROPN
admet-2684	450	16	.	.	PUNCT
admet-2684	451	1	antimicrobial	antimicrobial	ADJ
admet-2684	451	2	susceptibility	susceptibility	NOUN
admet-2684	451	3	testing	testing	NOUN
admet-2684	451	4	protocols	protocol	NOUN
admet-2684	451	5	,	,	PUNCT
admet-2684	451	6	crc	crc	NOUN
admet-2684	451	7	press	press	PROPN
admet-2684	451	8	,	,	PUNCT
admet-2684	451	9	boca	boca	PROPN
admet-2684	451	10	raton	raton	PROPN
admet-2684	451	11	,	,	PUNCT
admet-2684	451	12	fl	fl	PROPN
admet-2684	451	13	,	,	PUNCT
admet-2684	451	14	usa	usa	PROPN
admet-2684	451	15	,	,	PUNCT
admet-2684	451	16	2007	2007	NUM
admet-2684	451	17	.	.	PUNCT
admet-2684	452	1	https://doi.org/10.1201/9781420014495	https://doi.org/10.1201/9781420014495	PROPN
admet-2684	453	1	[	[	X
admet-2684	453	2	60	60	NUM
admet-2684	453	3	]	]	PUNCT
admet-2684	453	4	measuring	measure	VERB
admet-2684	453	5	cell	cell	NOUN
admet-2684	453	6	viability	viability	NOUN
admet-2684	453	7	/	/	SYM
admet-2684	453	8	cytotoxicity	cytotoxicity	NOUN
admet-2684	453	9	.	.	PUNCT
admet-2684	454	1	dojindo	dojindo	PROPN
admet-2684	454	2	eu	eu	PROPN
admet-2684	454	3	gmbh	gmbh	PROPN
admet-2684	454	4	,	,	PUNCT
admet-2684	454	5	munich	munich	PROPN
admet-2684	454	6	,	,	PUNCT
admet-2684	454	7	germany	germany	PROPN
admet-2684	454	8	.	.	PUNCT
admet-2684	455	1	https://www.dojindo.eu.com/protocol/dojindo-cell-proliferation-protocol.pdf	https://www.dojindo.eu.com/protocol/dojindo-cell-proliferation-protocol.pdf	PROPN
admet-2684	456	1	[	[	X
admet-2684	456	2	61	61	NUM
admet-2684	456	3	]	]	X
admet-2684	456	4	e.	e.	PROPN
admet-2684	456	5	grela	grela	PROPN
admet-2684	456	6	,	,	PUNCT
admet-2684	456	7	j.	j.	PROPN
admet-2684	456	8	kozłowska	kozłowska	PROPN
admet-2684	456	9	,	,	PUNCT
admet-2684	456	10	a.	a.	NOUN
admet-2684	456	11	grabowiecka	grabowiecka	PROPN
admet-2684	456	12	.	.	PUNCT
admet-2684	457	1	current	current	ADJ
admet-2684	457	2	methodology	methodology	NOUN
admet-2684	457	3	of	of	ADP
admet-2684	457	4	mtt	mtt	NOUN
admet-2684	457	5	assay	assay	VERB
admet-2684	457	6	in	in	ADP
admet-2684	457	7	bacteria	bacteria	NOUN
admet-2684	457	8	—	—	PUNCT
admet-2684	457	9	a	a	DET
admet-2684	457	10	review	review	NOUN
admet-2684	457	11	.	.	PUNCT
admet-2684	458	1	acta	acta	PROPN
admet-2684	458	2	histochemica	histochemica	ADP
admet-2684	458	3	120	120	NUM
admet-2684	458	4	(	(	PUNCT
admet-2684	458	5	2018	2018	NUM
admet-2684	458	6	)	)	PUNCT
admet-2684	458	7	303	303	NUM
admet-2684	458	8	-	-	SYM
admet-2684	458	9	311	311	NUM
admet-2684	458	10	.	.	PUNCT
admet-2684	459	1	https://doi.org/10.1016/j.acthis.2018.03.007	https://doi.org/10.1016/j.acthis.2018.03.007	NUM
admet-2684	459	2	[	[	X
admet-2684	459	3	62	62	NUM
admet-2684	459	4	]	]	PUNCT
admet-2684	459	5	graphpad	graphpad	NOUN
admet-2684	459	6	prism	prism	NOUN
admet-2684	459	7	5.00	5.00	NUM
admet-2684	459	8	software	software	NOUN
admet-2684	459	9	.	.	PUNCT
admet-2684	460	1	graphpadsoftware	graphpadsoftware	PROPN
admet-2684	460	2	,	,	PUNCT
admet-2684	460	3	san	san	PROPN
admet-2684	460	4	diego	diego	PROPN
admet-2684	460	5	,	,	PUNCT
admet-2684	460	6	ca	ca	PROPN
admet-2684	460	7	,	,	PUNCT
admet-2684	460	8	usa	usa	PROPN
admet-2684	460	9	.	.	PROPN
admet-2684	460	10	http://www.graphpad.com	http://www.graphpad.com	X
admet-2684	461	1	[	[	X
admet-2684	461	2	63	63	NUM
admet-2684	461	3	]	]	PUNCT
admet-2684	461	4	progenesis	progenesis	NOUN
admet-2684	461	5	qi	qi	NOUN
admet-2684	461	6	4.0	4.0	NUM
admet-2684	461	7	.	.	PUNCT
admet-2684	462	1	waters	water	NOUN
admet-2684	462	2	,	,	PUNCT
admet-2684	462	3	milford	milford	PROPN
admet-2684	462	4	,	,	PUNCT
admet-2684	462	5	usa	usa	PROPN
admet-2684	462	6	,	,	PUNCT
admet-2684	462	7	https://www.waters.com/nextgen/us/en/products/informaticsand-software/mass-spectrometry-software/progenesis-qi-software.html	https://www.waters.com/nextgen/us/en/products/informaticsand-software/mass-spectrometry-software/progenesis-qi-software.html	VERB
admet-2684	463	1	[	[	X
admet-2684	463	2	64	64	NUM
admet-2684	463	3	]	]	PUNCT
admet-2684	463	4	uniprot	uniprot	ADJ
admet-2684	463	5	:	:	PUNCT
admet-2684	463	6	the	the	DET
admet-2684	463	7	universal	universal	ADJ
admet-2684	463	8	protein	protein	NOUN
admet-2684	463	9	knowledgebase	knowledgebase	NOUN
admet-2684	463	10	in	in	ADP
admet-2684	463	11	2023	2023	NUM
admet-2684	463	12	.	.	PUNCT
admet-2684	464	1	https://www.uniprot.org/	https://www.uniprot.org/	X
admet-2684	465	1	[	[	X
admet-2684	465	2	65	65	NUM
admet-2684	465	3	]	]	PUNCT
admet-2684	465	4	k.	k.	PROPN
admet-2684	465	5	wu	wu	PROPN
admet-2684	465	6	,	,	PUNCT
admet-2684	465	7	s.h	s.h	PROPN
admet-2684	465	8	.	.	PROPN
admet-2684	465	9	kwon	kwon	PROPN
admet-2684	465	10	,	,	PUNCT
admet-2684	465	11	x.	x.	PROPN
admet-2684	465	12	zhou	zhou	PROPN
admet-2684	465	13	,	,	PUNCT
admet-2684	465	14	c.	c.	PROPN
admet-2684	465	15	fuller	fuller	NOUN
admet-2684	465	16	,	,	PUNCT
admet-2684	465	17	x.	x.	PROPN
admet-2684	465	18	wang	wang	PROPN
admet-2684	465	19	,	,	PUNCT
admet-2684	465	20	j.	j.	PROPN
admet-2684	465	21	vadgama	vadgama	PROPN
admet-2684	465	22	,	,	PUNCT
admet-2684	465	23	y.	y.	PROPN
admet-2684	465	24	wu	wu	PROPN
admet-2684	465	25	.	.	PUNCT
admet-2684	466	1	overcoming	overcome	VERB
admet-2684	466	2	challenges	challenge	NOUN
admet-2684	466	3	in	in	ADP
admet-2684	466	4	smallmolecule	smallmolecule	ADJ
admet-2684	466	5	drug	drug	NOUN
admet-2684	466	6	bioavailability	bioavailability	NOUN
admet-2684	466	7	:	:	PUNCT
admet-2684	466	8	a	a	DET
admet-2684	466	9	review	review	NOUN
admet-2684	466	10	of	of	ADP
admet-2684	466	11	key	key	ADJ
admet-2684	466	12	factors	factor	NOUN
admet-2684	466	13	and	and	CCONJ
admet-2684	466	14	approaches	approach	NOUN
admet-2684	466	15	.	.	PUNCT
admet-2684	467	1	international	international	ADJ
admet-2684	467	2	journal	journal	NOUN
admet-2684	467	3	of	of	ADP
admet-2684	467	4	molecular	molecular	ADJ
admet-2684	467	5	sciences	science	NOUN
admet-2684	467	6	25	25	NUM
admet-2684	467	7	(	(	PUNCT
admet-2684	467	8	2024	2024	NUM
admet-2684	467	9	)	)	PUNCT
admet-2684	467	10	13121	13121	NUM
admet-2684	467	11	.	.	PUNCT
admet-2684	468	1	https://doi.org/10.3390/ijms252313121	https://doi.org/10.3390/ijms252313121	VERB
admet-2684	468	2	[	[	X
admet-2684	468	3	66	66	NUM
admet-2684	468	4	]	]	PUNCT
admet-2684	468	5	acd	acd	PROPN
admet-2684	468	6	/	/	SYM
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admet-2684	468	9	.	.	PROPN
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admet-2684	468	11	.	.	PUNCT
admet-2684	469	1	advanced	advanced	ADJ
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admet-2684	469	3	development	development	PROPN
admet-2684	469	4	,	,	PUNCT
admet-2684	469	5	inc	inc	PROPN
admet-2684	469	6	.	.	PROPN
admet-2684	469	7	,	,	PUNCT
admet-2684	469	8	toronto	toronto	PROPN
admet-2684	469	9	,	,	PUNCT
admet-2684	469	10	on	on	ADP
admet-2684	469	11	,	,	PUNCT
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admet-2684	469	13	,	,	PUNCT
admet-2684	469	14	2012	2012	NUM
admet-2684	469	15	.	.	PUNCT
admet-2684	470	1	https://www.acdlabs.com/products/percepta-platform/	https://www.acdlabs.com/products/percepta-platform/	X
admet-2684	470	2	[	[	X
admet-2684	470	3	67	67	NUM
admet-2684	470	4	]	]	X
admet-2684	470	5	c.a	c.a	PROPN
admet-2684	470	6	.	.	PROPN
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admet-2684	470	8	,	,	PUNCT
admet-2684	470	9	f.	f.	PROPN
admet-2684	470	10	lombardo	lombardo	PROPN
admet-2684	470	11	,	,	PUNCT
admet-2684	470	12	b.w	b.w	PROPN
admet-2684	470	13	.	.	PROPN
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admet-2684	470	15	,	,	PUNCT
admet-2684	470	16	p.j	p.j	PROPN
admet-2684	470	17	.	.	PROPN
admet-2684	470	18	feeney	feeney	PROPN
admet-2684	470	19	.	.	PUNCT
admet-2684	471	1	experimental	experimental	ADJ
admet-2684	471	2	and	and	CCONJ
admet-2684	471	3	computational	computational	ADJ
admet-2684	471	4	approaches	approach	NOUN
admet-2684	471	5	to	to	PART
admet-2684	471	6	estimate	estimate	VERB
admet-2684	471	7	solubility	solubility	NOUN
admet-2684	471	8	and	and	CCONJ
admet-2684	471	9	permeability	permeability	NOUN
admet-2684	471	10	in	in	ADP
admet-2684	471	11	drug	drug	NOUN
admet-2684	471	12	discovery	discovery	NOUN
admet-2684	471	13	and	and	CCONJ
admet-2684	471	14	development	development	NOUN
admet-2684	471	15	settings	setting	NOUN
admet-2684	471	16	.	.	PUNCT
admet-2684	472	1	advanced	advanced	ADJ
admet-2684	472	2	drug	drug	NOUN
admet-2684	472	3	delivery	delivery	NOUN
admet-2684	472	4	reviews	review	VERB
admet-2684	472	5	46	46	NUM
admet-2684	472	6	(	(	PUNCT
admet-2684	472	7	2001	2001	NUM
admet-2684	472	8	)	)	PUNCT
admet-2684	472	9	3	3	NUM
admet-2684	472	10	-	-	SYM
admet-2684	472	11	26	26	NUM
admet-2684	472	12	.	.	PUNCT
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admet-2684	473	4	]	]	X
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admet-2684	473	10	di	di	PROPN
admet-2684	473	11	.	.	PROPN
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admet-2684	473	13	-	-	PUNCT
admet-2684	473	14	like	like	ADJ
admet-2684	473	15	properties	property	NOUN
admet-2684	473	16	:	:	PUNCT
admet-2684	473	17	concepts	concept	NOUN
admet-2684	473	18	.	.	PUNCT
admet-2684	474	1	structure	structure	NOUN
admet-2684	474	2	design	design	NOUN
admet-2684	474	3	and	and	CCONJ
admet-2684	474	4	methods	method	NOUN
admet-2684	474	5	:	:	PUNCT
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admet-2684	474	7	adme	adme	NOUN
admet-2684	474	8	to	to	ADP
admet-2684	474	9	toxicity	toxicity	NOUN
admet-2684	474	10	optimization	optimization	NOUN
admet-2684	474	11	;	;	PUNCT
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admet-2684	474	13	press	press	NOUN
admet-2684	474	14	,	,	PUNCT
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admet-2684	474	16	diego	diego	PROPN
admet-2684	474	17	,	,	PUNCT
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admet-2684	474	19	,	,	PUNCT
admet-2684	474	20	usa	usa	PROPN
admet-2684	474	21	,	,	PUNCT
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admet-2684	474	23	.	.	PUNCT
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admet-2684	475	2	978	978	NUM
admet-2684	475	3	-	-	SYM
admet-2684	475	4	0	0	NUM
admet-2684	475	5	-	-	PUNCT
admet-2684	475	6	12	12	NUM
admet-2684	475	7	-	-	PUNCT
admet-2684	475	8	369520	369520	NUM
admet-2684	475	9	-	-	SYM
admet-2684	475	10	8	8	NUM
admet-2684	475	11	[	[	X
admet-2684	475	12	69	69	NUM
admet-2684	475	13	]	]	X
admet-2684	475	14	d.f	d.f	PROPN
admet-2684	475	15	.	.	PROPN
admet-2684	475	16	veber	veber	PROPN
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admet-2684	475	19	.	.	PROPN
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admet-2684	475	35	.	.	PROPN
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admet-2684	475	37	.	.	PUNCT
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admet-2684	476	11	.	.	PUNCT
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admet-2684	477	4	chemistry	chemistry	NOUN
admet-2684	477	5	45	45	NUM
admet-2684	477	6	(	(	PUNCT
admet-2684	477	7	2002	2002	NUM
admet-2684	477	8	)	)	PUNCT
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admet-2684	477	10	.	.	PUNCT
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admet-2684	479	9	.	.	PROPN
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admet-2684	480	5	vivo	vivo	ADJ
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admet-2684	480	8	adme	adme	NOUN
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admet-2684	480	14	selection	selection	NOUN
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admet-2684	480	18	guidelines	guideline	NOUN
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admet-2684	480	21	and	and	CCONJ
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admet-2684	481	18	center	center	NOUN
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admet-2684	481	26	https://doi.org/10.1007/s10096-006-0153-8	https://doi.org/10.1007/s10096-006-0153-8	NUM
admet-2684	481	27	https://doi.org/10.1007/s10096-006-0153-8	https://doi.org/10.1007/s10096-006-0153-8	NUM
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admet-2684	481	32	https://doi.org/10.1016/j.acthis.2018.03.007	https://doi.org/10.1016/j.acthis.2018.03.007	PROPN
admet-2684	481	33	http://www.graphpad.com/	http://www.graphpad.com/	PROPN
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admet-2684	481	35	https://www.waters.com/nextgen/us/en/products/informatics-and-software/mass-spectrometry-software/progenesis-qi-software.html?srsltid=afmbooreps6r4vmhqzywmfprcrmg4xw3yx3sabxg8z0mxtgocdlayf-q	https://www.waters.com/nextgen/us/en/products/informatics-and-software/mass-spectrometry-software/progenesis-qi-software.html?srsltid=afmbooreps6r4vmhqzywmfprcrmg4xw3yx3sabxg8z0mxtgocdlayf-q	PROPN
admet-2684	481	36	https://www.uniprot.org/	https://www.uniprot.org/	X
admet-2684	481	37	https://doi.org/10.3390/ijms252313121	https://doi.org/10.3390/ijms252313121	VERB
admet-2684	481	38	https://www.acdlabs.com/products/percepta-platform/	https://www.acdlabs.com/products/percepta-platform/	PUNCT
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admet-2684	481	40	https://doi.org/10.1021/jm020017n	https://doi.org/10.1021/jm020017n	X
admet-2684	481	41	admet	admet	NOUN
admet-2684	481	42	&	&	CCONJ
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admet-2684	481	44	13(2	13(2	PROPN
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admet-2684	481	47	2025	2025	NUM
admet-2684	481	48	)	)	PUNCT
admet-2684	481	49	2684	2684	NUM
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admet-2684	481	51	effect	effect	NOUN
admet-2684	481	52	of	of	ADP
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admet-2684	481	55	-	-	PUNCT
admet-2684	481	56	hydroxynaphthalene-2	hydroxynaphthalene-2	NUM
admet-2684	481	57	-	-	PUNCT
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admet-2684	481	60	:	:	PUNCT
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admet-2684	485	1	intra	intra	ADJ
admet-2684	485	2	-	-	ADJ
admet-2684	485	3	science	science	ADJ
admet-2684	485	4	chemistry	chemistry	NOUN
admet-2684	485	5	reports	report	VERB
admet-2684	485	6	8	8	NUM
admet-2684	485	7	(	(	PUNCT
admet-2684	485	8	1974	1974	NUM
admet-2684	485	9	)	)	PUNCT
admet-2684	485	10	17	17	NUM
admet-2684	485	11	-	-	SYM
admet-2684	485	12	25	25	NUM
admet-2684	485	13	.	.	PUNCT
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admet-2684	486	11	,	,	PUNCT
admet-2684	486	12	w.	w.	PROPN
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admet-2684	487	13	activities	activity	NOUN
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admet-2684	488	9	(	(	PUNCT
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admet-2684	488	11	)	)	PUNCT
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admet-2684	488	13	-	-	SYM
admet-2684	488	14	658	658	NUM
admet-2684	488	15	.	.	PUNCT
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admet-2684	492	3	(	(	PUNCT
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admet-2684	492	5	)	)	PUNCT
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admet-2684	495	7	(	(	PUNCT
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admet-2684	495	12	.	.	PUNCT
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admet-2684	497	6	.	.	PUNCT
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admet-2684	499	3	]	]	PUNCT
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admet-2684	504	10	.	.	PUNCT
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admet-2684	505	6	(	(	PUNCT
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admet-2684	505	8	)	)	PUNCT
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admet-2684	505	10	-	-	SYM
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admet-2684	507	10	.	.	PUNCT
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admet-2684	508	3	(	(	PUNCT
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admet-2684	508	7	.	.	PUNCT
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admet-2684	511	8	)	)	PUNCT
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