id	sid	tid	token	lemma	pos
admet-2766	1	1	crispr	crispr	ADJ
admet-2766	1	2	-	-	PUNCT
admet-2766	1	3	cas9	cas9	NOUN
admet-2766	1	4	based	base	VERB
admet-2766	1	5	electrochemical	electrochemical	ADJ
admet-2766	1	6	biosensor	biosensor	NOUN
admet-2766	1	7	for	for	ADP
admet-2766	1	8	the	the	DET
admet-2766	1	9	detection	detection	NOUN
admet-2766	1	10	of	of	ADP
admet-2766	1	11	katg	katg	PROPN
admet-2766	1	12	gene	gene	NOUN
admet-2766	1	13	mutations	mutation	NOUN
admet-2766	1	14	in	in	ADP
admet-2766	1	15	isoniazid	isoniazid	NOUN
admet-2766	1	16	-	-	PUNCT
admet-2766	1	17	resistant	resistant	ADJ
admet-2766	1	18	tuberculosis	tuberculosis	NOUN
admet-2766	1	19	doi	doi	NOUN
admet-2766	1	20	:	:	PUNCT
admet-2766	1	21	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	1	22	1	1	NUM
admet-2766	1	23	admet	admet	X
admet-2766	1	24	&	&	CCONJ
admet-2766	1	25	dmpk	dmpk	PROPN
admet-2766	1	26	13(3	13(3	NUM
admet-2766	1	27	)	)	PUNCT
admet-2766	1	28	(	(	PUNCT
admet-2766	1	29	2025	2025	NUM
admet-2766	1	30	)	)	PUNCT
admet-2766	1	31	2766	2766	NUM
admet-2766	1	32	;	;	PUNCT
admet-2766	1	33	doi	doi	NOUN
admet-2766	1	34	:	:	PUNCT
admet-2766	1	35	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	1	36	open	open	ADJ
admet-2766	1	37	access	access	NOUN
admet-2766	1	38	:	:	PUNCT
admet-2766	1	39	issn	issn	PROPN
admet-2766	1	40	:	:	PUNCT
admet-2766	1	41	1848	1848	NUM
admet-2766	1	42	-	-	SYM
admet-2766	1	43	7718	7718	NUM
admet-2766	1	44	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-2766	1	45	original	original	ADJ
admet-2766	1	46	scientific	scientific	ADJ
admet-2766	1	47	paper	paper	NOUN
admet-2766	1	48	crispr	crispr	NOUN
admet-2766	1	49	-	-	PUNCT
admet-2766	1	50	cas9	cas9	NOUN
admet-2766	1	51	-	-	PUNCT
admet-2766	1	52	based	base	VERB
admet-2766	1	53	electrochemical	electrochemical	ADJ
admet-2766	1	54	biosensor	biosensor	NOUN
admet-2766	1	55	for	for	ADP
admet-2766	1	56	the	the	DET
admet-2766	1	57	detection	detection	NOUN
admet-2766	1	58	of	of	ADP
admet-2766	1	59	katg	katg	PROPN
admet-2766	1	60	gene	gene	NOUN
admet-2766	1	61	mutations	mutation	NOUN
admet-2766	1	62	in	in	ADP
admet-2766	1	63	isoniazid	isoniazid	NOUN
admet-2766	1	64	-	-	PUNCT
admet-2766	1	65	resistant	resistant	ADJ
admet-2766	1	66	tuberculosis	tuberculosis	NOUN
admet-2766	1	67	dika	dika	NOUN
admet-2766	1	68	apriliana	apriliana	VERB
admet-2766	1	69	wulandari1	wulandari1	PROPN
admet-2766	1	70	,	,	PUNCT
admet-2766	1	71	muhammad	muhammad	PROPN
admet-2766	1	72	ihda	ihda	PROPN
admet-2766	1	73	hamlu	hamlu	PROPN
admet-2766	1	74	liwaissunati	liwaissunati	PROPN
admet-2766	1	75	zein2	zein2	PROPN
admet-2766	1	76	,	,	PUNCT
admet-2766	1	77	salma	salma	PROPN
admet-2766	1	78	nur	nur	PROPN
admet-2766	1	79	zakiyyah1	zakiyyah1	PROPN
admet-2766	1	80	,	,	PUNCT
admet-2766	1	81	safri	safri	PROPN
admet-2766	1	82	ishmayana1	ishmayana1	PROPN
admet-2766	1	83	,	,	PUNCT
admet-2766	1	84	mehmet	mehmet	PROPN
admet-2766	1	85	ozsoz1,3	ozsoz1,3	PROPN
admet-2766	1	86	,	,	PUNCT
admet-2766	1	87	yeni	yeni	PROPN
admet-2766	1	88	wahyuni	wahyuni	PROPN
admet-2766	1	89	hartati1,4	hartati1,4	PROPN
admet-2766	1	90	,	,	PUNCT
admet-2766	1	91	*	*	PUNCT
admet-2766	1	92	and	and	CCONJ
admet-2766	1	93	irkham1,4,	irkham1,4,	VERB
admet-2766	1	94	1department	1department	NUM
admet-2766	1	95	of	of	ADP
admet-2766	1	96	chemistry	chemistry	NOUN
admet-2766	1	97	,	,	PUNCT
admet-2766	1	98	faculty	faculty	NOUN
admet-2766	1	99	of	of	ADP
admet-2766	1	100	mathematics	mathematic	NOUN
admet-2766	1	101	and	and	CCONJ
admet-2766	1	102	natural	natural	ADJ
admet-2766	1	103	science	science	NOUN
admet-2766	1	104	,	,	PUNCT
admet-2766	1	105	universitas	universita	NOUN
admet-2766	1	106	padjadjaran	padjadjaran	NOUN
admet-2766	1	107	,	,	PUNCT
admet-2766	1	108	sumedang	sumedang	PROPN
admet-2766	1	109	45363	45363	NUM
admet-2766	1	110	,	,	PUNCT
admet-2766	1	111	indonesia	indonesia	PROPN
admet-2766	1	112	2department	2department	NUM
admet-2766	1	113	of	of	ADP
admet-2766	1	114	chemistry	chemistry	NOUN
admet-2766	1	115	“	"	PUNCT
admet-2766	1	116	giacomo	giacomo	NOUN
admet-2766	1	117	ciamician	ciamician	NOUN
admet-2766	1	118	”	"	PUNCT
admet-2766	1	119	,	,	PUNCT
admet-2766	1	120	alma	alma	NOUN
admet-2766	1	121	mater	mater	PROPN
admet-2766	1	122	studiorum	studiorum	PROPN
admet-2766	1	123	university	university	PROPN
admet-2766	1	124	of	of	ADP
admet-2766	1	125	bologna	bologna	PROPN
admet-2766	1	126	,	,	PUNCT
admet-2766	1	127	bologna	bologna	PROPN
admet-2766	1	128	40126	40126	NUM
admet-2766	1	129	,	,	PUNCT
admet-2766	1	130	italy	italy	PROPN
admet-2766	2	1	3department	3department	NUM
admet-2766	2	2	of	of	ADP
admet-2766	2	3	biomedical	biomedical	ADJ
admet-2766	2	4	engineering	engineering	NOUN
admet-2766	2	5	,	,	PUNCT
admet-2766	2	6	near	near	ADP
admet-2766	2	7	east	east	PROPN
admet-2766	2	8	university	university	PROPN
admet-2766	2	9	,	,	PUNCT
admet-2766	2	10	mersin	mersin	PROPN
admet-2766	2	11	99138	99138	NUM
admet-2766	2	12	,	,	PUNCT
admet-2766	2	13	turkey	turkey	PROPN
admet-2766	2	14	4study	4study	NUM
admet-2766	2	15	center	center	NOUN
admet-2766	2	16	of	of	ADP
admet-2766	2	17	sensor	sensor	NOUN
admet-2766	2	18	and	and	CCONJ
admet-2766	2	19	green	green	ADJ
admet-2766	2	20	chemistry	chemistry	NOUN
admet-2766	2	21	,	,	PUNCT
admet-2766	2	22	faculty	faculty	NOUN
admet-2766	2	23	of	of	ADP
admet-2766	2	24	mathematics	mathematic	NOUN
admet-2766	2	25	and	and	CCONJ
admet-2766	2	26	natural	natural	ADJ
admet-2766	2	27	science	science	NOUN
admet-2766	2	28	,	,	PUNCT
admet-2766	2	29	universitas	universita	NOUN
admet-2766	2	30	padjadjaran	padjadjaran	NOUN
admet-2766	2	31	,	,	PUNCT
admet-2766	2	32	bandung	bandung	PROPN
admet-2766	2	33	40132	40132	NUM
admet-2766	2	34	,	,	PUNCT
admet-2766	2	35	indonesia	indonesia	PROPN
admet-2766	2	36	corresponding	correspond	VERB
admet-2766	2	37	authors	author	NOUN
admet-2766	2	38	:	:	PUNCT
admet-2766	2	39	e	e	X
admet-2766	2	40	-	-	NOUN
admet-2766	2	41	mail	mail	NOUN
admet-2766	2	42	:	:	PUNCT
admet-2766	2	43	*	*	PUNCT
admet-2766	2	44	yeni.w.hartati@unpad.ac.id	yeni.w.hartati@unpad.ac.id	PROPN
admet-2766	2	45	;	;	PUNCT
admet-2766	2	46	irkham@unpad.ac.id	irkham@unpad.ac.id	PUNCT
admet-2766	2	47	received	receive	VERB
admet-2766	2	48	:	:	PUNCT
admet-2766	2	49	april	april	PROPN
admet-2766	2	50	12	12	NUM
admet-2766	2	51	,	,	PUNCT
admet-2766	2	52	2025	2025	NUM
admet-2766	2	53	;	;	PUNCT
admet-2766	2	54	revised	revise	VERB
admet-2766	2	55	:	:	PUNCT
admet-2766	2	56	june	june	PROPN
admet-2766	2	57	5	5	NUM
admet-2766	2	58	,	,	PUNCT
admet-2766	2	59	2025	2025	NUM
admet-2766	2	60	;	;	PUNCT
admet-2766	2	61	published	publish	VERB
admet-2766	2	62	:	:	PUNCT
admet-2766	2	63	june	june	PROPN
admet-2766	2	64	17	17	NUM
admet-2766	2	65	,	,	PUNCT
admet-2766	2	66	2025	2025	NUM
admet-2766	2	67	abstract	abstract	ADJ
admet-2766	2	68	background	background	NOUN
admet-2766	2	69	and	and	CCONJ
admet-2766	2	70	purpose	purpose	NOUN
admet-2766	2	71	:	:	PUNCT
admet-2766	2	72	multidrug	multidrug	NOUN
admet-2766	2	73	-	-	PUNCT
admet-2766	2	74	resistant	resistant	ADJ
admet-2766	2	75	tuberculosis	tuberculosis	NOUN
admet-2766	2	76	(	(	PUNCT
admet-2766	2	77	mdr	mdr	PROPN
admet-2766	2	78	-	-	NOUN
admet-2766	2	79	tb	tb	NOUN
admet-2766	2	80	)	)	PUNCT
admet-2766	2	81	remains	remain	VERB
admet-2766	2	82	a	a	DET
admet-2766	2	83	significant	significant	ADJ
admet-2766	2	84	challenge	challenge	NOUN
admet-2766	2	85	in	in	ADP
admet-2766	2	86	tuberculosis	tuberculosis	NOUN
admet-2766	2	87	(	(	PUNCT
admet-2766	2	88	tb	tb	NOUN
admet-2766	2	89	)	)	PUNCT
admet-2766	2	90	treatment	treatment	NOUN
admet-2766	2	91	,	,	PUNCT
admet-2766	2	92	driven	drive	VERB
admet-2766	2	93	by	by	ADP
admet-2766	2	94	simultaneous	simultaneous	ADJ
admet-2766	2	95	mutations	mutation	NOUN
admet-2766	2	96	in	in	ADP
admet-2766	2	97	the	the	DET
admet-2766	2	98	rpob	rpob	PROPN
admet-2766	2	99	and	and	CCONJ
admet-2766	2	100	katg	katg	PROPN
admet-2766	2	101	genes	gene	NOUN
admet-2766	2	102	that	that	PRON
admet-2766	2	103	confer	confer	VERB
admet-2766	2	104	resistance	resistance	NOUN
admet-2766	2	105	to	to	ADP
admet-2766	2	106	rifampicin	rifampicin	NOUN
admet-2766	2	107	and	and	CCONJ
admet-2766	2	108	isoniazid	isoniazid	NOUN
admet-2766	2	109	.	.	PUNCT
admet-2766	3	1	while	while	SCONJ
admet-2766	3	2	many	many	ADJ
admet-2766	3	3	molecular	molecular	ADJ
admet-2766	3	4	diagnostic	diagnostic	ADJ
admet-2766	3	5	tools	tool	NOUN
admet-2766	3	6	focus	focus	VERB
admet-2766	3	7	on	on	ADP
admet-2766	3	8	rpob	rpob	PROPN
admet-2766	3	9	,	,	PUNCT
admet-2766	3	10	the	the	DET
admet-2766	3	11	katg	katg	PROPN
admet-2766	3	12	gene	gene	NOUN
admet-2766	3	13	is	be	AUX
admet-2766	3	14	often	often	ADV
admet-2766	3	15	overlooked	overlook	VERB
admet-2766	3	16	despite	despite	SCONJ
admet-2766	3	17	its	its	PRON
admet-2766	3	18	critical	critical	ADJ
admet-2766	3	19	role	role	NOUN
admet-2766	3	20	in	in	ADP
admet-2766	3	21	confirming	confirm	VERB
admet-2766	3	22	mdr	mdr	PROPN
admet-2766	3	23	-	-	PROPN
admet-2766	3	24	tb	tb	PROPN
admet-2766	3	25	.	.	PUNCT
admet-2766	4	1	this	this	DET
admet-2766	4	2	study	study	NOUN
admet-2766	4	3	aims	aim	VERB
admet-2766	4	4	to	to	PART
admet-2766	4	5	develop	develop	VERB
admet-2766	4	6	a	a	DET
admet-2766	4	7	crispr	crispr	NOUN
admet-2766	4	8	/	/	SYM
admet-2766	4	9	cas9based	cas9base	VERB
admet-2766	4	10	electrochemical	electrochemical	ADJ
admet-2766	4	11	biosensor	biosensor	NOUN
admet-2766	4	12	for	for	ADP
admet-2766	4	13	the	the	DET
admet-2766	4	14	rapid	rapid	ADJ
admet-2766	4	15	and	and	CCONJ
admet-2766	4	16	selective	selective	ADJ
admet-2766	4	17	detection	detection	NOUN
admet-2766	4	18	of	of	ADP
admet-2766	4	19	katg	katg	PROPN
admet-2766	4	20	mutation	mutation	NOUN
admet-2766	4	21	.	.	PUNCT
admet-2766	5	1	experimental	experimental	ADJ
admet-2766	5	2	approach	approach	NOUN
admet-2766	5	3	:	:	PUNCT
admet-2766	5	4	a	a	DET
admet-2766	5	5	guide	guide	NOUN
admet-2766	5	6	rna	rna	NOUN
admet-2766	5	7	(	(	PUNCT
admet-2766	5	8	grna	grna	NOUN
admet-2766	5	9	)	)	PUNCT
admet-2766	5	10	specific	specific	ADJ
admet-2766	5	11	to	to	ADP
admet-2766	5	12	the	the	DET
admet-2766	5	13	mutation	mutation	NOUN
admet-2766	5	14	site	site	NOUN
admet-2766	5	15	on	on	ADP
admet-2766	5	16	katg	katg	PROPN
admet-2766	5	17	gene	gene	NOUN
admet-2766	5	18	was	be	AUX
admet-2766	5	19	designed	design	VERB
admet-2766	5	20	using	use	VERB
admet-2766	5	21	the	the	DET
admet-2766	5	22	benchling	benchle	VERB
admet-2766	5	23	crispr	crispr	ADJ
admet-2766	5	24	tool	tool	NOUN
admet-2766	5	25	,	,	PUNCT
admet-2766	5	26	considering	consider	VERB
admet-2766	5	27	on	on	ADP
admet-2766	5	28	-	-	PUNCT
admet-2766	5	29	target	target	NOUN
admet-2766	5	30	and	and	CCONJ
admet-2766	5	31	off	off	ADP
admet-2766	5	32	-	-	PUNCT
admet-2766	5	33	target	target	NOUN
admet-2766	5	34	scores	score	NOUN
admet-2766	5	35	,	,	PUNCT
admet-2766	5	36	specificity	specificity	NOUN
admet-2766	5	37	,	,	PUNCT
admet-2766	5	38	and	and	CCONJ
admet-2766	5	39	cleavage	cleavage	NOUN
admet-2766	5	40	sites	site	NOUN
admet-2766	5	41	within	within	ADP
admet-2766	5	42	the	the	DET
admet-2766	5	43	mycobacterium	mycobacterium	NOUN
admet-2766	5	44	tuberculosis	tuberculosis	NOUN
admet-2766	5	45	genome	genome	NOUN
admet-2766	5	46	.	.	PUNCT
admet-2766	6	1	the	the	DET
admet-2766	6	2	selected	select	VERB
admet-2766	6	3	grna	grna	NOUN
admet-2766	6	4	achieved	achieve	VERB
admet-2766	6	5	the	the	DET
admet-2766	6	6	highest	high	ADJ
admet-2766	6	7	on	on	ADP
admet-2766	6	8	-	-	PUNCT
admet-2766	6	9	target	target	NOUN
admet-2766	6	10	score	score	NOUN
admet-2766	6	11	of	of	ADP
admet-2766	6	12	61.2	61.2	NUM
admet-2766	6	13	and	and	CCONJ
admet-2766	6	14	an	an	DET
admet-2766	6	15	off	off	ADJ
admet-2766	6	16	-	-	PUNCT
admet-2766	6	17	target	target	NOUN
admet-2766	6	18	score	score	NOUN
admet-2766	6	19	of	of	ADP
admet-2766	6	20	49.0	49.0	NUM
admet-2766	6	21	at	at	ADP
admet-2766	6	22	cut	cut	VERB
admet-2766	6	23	position	position	NOUN
admet-2766	6	24	2928	2928	NUM
admet-2766	6	25	,	,	PUNCT
admet-2766	6	26	with	with	ADP
admet-2766	6	27	a	a	DET
admet-2766	6	28	pam	pam	NOUN
admet-2766	6	29	sequence	sequence	NOUN
admet-2766	6	30	of	of	ADP
admet-2766	6	31	agg	agg	PROPN
admet-2766	6	32	.	.	PUNCT
admet-2766	7	1	its	its	PRON
admet-2766	7	2	cleavage	cleavage	NOUN
admet-2766	7	3	efficiency	efficiency	NOUN
admet-2766	7	4	was	be	AUX
admet-2766	7	5	validated	validate	VERB
admet-2766	7	6	experimentally	experimentally	ADV
admet-2766	7	7	using	use	VERB
admet-2766	7	8	an	an	DET
admet-2766	7	9	electrochemical	electrochemical	ADJ
admet-2766	7	10	biosensing	biosensing	NOUN
admet-2766	7	11	platform	platform	NOUN
admet-2766	7	12	incorporating	incorporate	VERB
admet-2766	7	13	a	a	DET
admet-2766	7	14	gold	gold	NOUN
admet-2766	7	15	-	-	PUNCT
admet-2766	7	16	modified	modify	VERB
admet-2766	7	17	screen	screen	NOUN
admet-2766	7	18	-	-	PUNCT
admet-2766	7	19	printed	print	VERB
admet-2766	7	20	carbon	carbon	NOUN
admet-2766	7	21	electrode	electrode	NOUN
admet-2766	7	22	(	(	PUNCT
admet-2766	7	23	spce	spce	PROPN
admet-2766	7	24	/	/	SYM
admet-2766	7	25	au	au	PROPN
admet-2766	7	26	)	)	PUNCT
admet-2766	7	27	.	.	PUNCT
admet-2766	8	1	redox	redox	ADJ
admet-2766	8	2	response	response	NOUN
admet-2766	8	3	enhancement	enhancement	NOUN
admet-2766	8	4	by	by	ADP
admet-2766	8	5	[	[	PUNCT
admet-2766	8	6	fe(cn6)]3-/4confirmed	fe(cn6)]3-/4confirmed	ADJ
admet-2766	8	7	the	the	DET
admet-2766	8	8	improved	improved	ADJ
admet-2766	8	9	performance	performance	NOUN
admet-2766	8	10	of	of	ADP
admet-2766	8	11	the	the	DET
admet-2766	8	12	electrode	electrode	NOUN
admet-2766	8	13	.	.	PUNCT
admet-2766	9	1	key	key	ADJ
admet-2766	9	2	results	result	NOUN
admet-2766	9	3	:	:	PUNCT
admet-2766	9	4	the	the	DET
admet-2766	9	5	biosensor	biosensor	NOUN
admet-2766	9	6	system	system	NOUN
admet-2766	9	7	detects	detect	VERB
admet-2766	9	8	the	the	DET
admet-2766	9	9	target	target	NOUN
admet-2766	9	10	dna	dna	NOUN
admet-2766	9	11	through	through	ADP
admet-2766	9	12	hybridization	hybridization	NOUN
admet-2766	9	13	with	with	ADP
admet-2766	9	14	dna	dna	PROPN
admet-2766	9	15	probe	probe	PROPN
admet-2766	9	16	-	-	PUNCT
admet-2766	9	17	fc	fc	PROPN
admet-2766	9	18	,	,	PUNCT
admet-2766	9	19	forming	form	VERB
admet-2766	9	20	double	double	ADJ
admet-2766	9	21	-	-	PUNCT
admet-2766	9	22	stranded	strand	VERB
admet-2766	9	23	dna	dna	NOUN
admet-2766	9	24	(	(	PUNCT
admet-2766	9	25	dsdna	dsdna	NOUN
admet-2766	9	26	)	)	PUNCT
admet-2766	9	27	that	that	PRON
admet-2766	9	28	is	be	AUX
admet-2766	9	29	recognized	recognize	VERB
admet-2766	9	30	and	and	CCONJ
admet-2766	9	31	cleaved	cleave	VERB
admet-2766	9	32	by	by	ADP
admet-2766	9	33	the	the	DET
admet-2766	9	34	cas9	cas9	NOUN
admet-2766	9	35	/	/	SYM
admet-2766	9	36	grna	grna	NOUN
admet-2766	9	37	complex	complex	NOUN
admet-2766	9	38	.	.	PUNCT
admet-2766	10	1	this	this	DET
admet-2766	10	2	cleavage	cleavage	NOUN
admet-2766	10	3	significantly	significantly	ADV
admet-2766	10	4	reduces	reduce	VERB
admet-2766	10	5	the	the	DET
admet-2766	10	6	ferrocene	ferrocene	NOUN
admet-2766	10	7	oxidation	oxidation	NOUN
admet-2766	10	8	signal	signal	NOUN
admet-2766	10	9	,	,	PUNCT
admet-2766	10	10	indicating	indicate	VERB
admet-2766	10	11	the	the	DET
admet-2766	10	12	presence	presence	NOUN
admet-2766	10	13	of	of	ADP
admet-2766	10	14	a	a	DET
admet-2766	10	15	katg	katg	NOUN
admet-2766	10	16	mutation	mutation	NOUN
admet-2766	10	17	.	.	PUNCT
admet-2766	11	1	non	non	ADJ
admet-2766	11	2	-	-	ADJ
admet-2766	11	3	mutated	mutated	ADJ
admet-2766	11	4	target	target	NOUN
admet-2766	11	5	dna	dna	PROPN
admet-2766	11	6	produces	produce	VERB
admet-2766	11	7	a	a	DET
admet-2766	11	8	nondetectable	nondetectable	ADJ
admet-2766	11	9	ferrocene	ferrocene	NOUN
admet-2766	11	10	signal	signal	NOUN
admet-2766	11	11	,	,	PUNCT
admet-2766	11	12	suggesting	suggest	VERB
admet-2766	11	13	that	that	SCONJ
admet-2766	11	14	the	the	DET
admet-2766	11	15	cas9	cas9	NOUN
admet-2766	11	16	enzyme	enzyme	NOUN
admet-2766	11	17	may	may	AUX
admet-2766	11	18	remain	remain	VERB
admet-2766	11	19	bound	bound	ADJ
admet-2766	11	20	to	to	ADP
admet-2766	11	21	the	the	DET
admet-2766	11	22	electrode	electrode	NOUN
admet-2766	11	23	without	without	ADP
admet-2766	11	24	cleavage	cleavage	NOUN
admet-2766	11	25	.	.	PUNCT
admet-2766	12	1	the	the	DET
admet-2766	12	2	crispr	crispr	ADJ
admet-2766	12	3	/	/	SYM
admet-2766	12	4	cas9	cas9	NOUN
admet-2766	12	5	electrochemical	electrochemical	ADJ
admet-2766	12	6	biosensor	biosensor	NOUN
admet-2766	12	7	demonstrated	demonstrate	VERB
admet-2766	12	8	a	a	DET
admet-2766	12	9	low	low	ADJ
admet-2766	12	10	detection	detection	NOUN
admet-2766	12	11	limit	limit	NOUN
admet-2766	12	12	of	of	ADP
admet-2766	12	13	7.5530	7.5530	NUM
admet-2766	12	14	am	am	NOUN
admet-2766	12	15	and	and	CCONJ
admet-2766	12	16	a	a	DET
admet-2766	12	17	detection	detection	NOUN
admet-2766	12	18	range	range	NOUN
admet-2766	12	19	of	of	ADP
admet-2766	12	20	101	101	NUM
admet-2766	12	21	to	to	PART
admet-2766	12	22	106	106	NUM
admet-2766	12	23	am	am	NOUN
admet-2766	12	24	.	.	PUNCT
admet-2766	13	1	conclusion	conclusion	NOUN
admet-2766	13	2	:	:	PUNCT
admet-2766	13	3	the	the	DET
admet-2766	13	4	crispr	crispr	ADJ
admet-2766	13	5	/	/	SYM
admet-2766	13	6	cas9	cas9	NOUN
admet-2766	13	7	-	-	PUNCT
admet-2766	13	8	based	base	VERB
admet-2766	13	9	electrochemical	electrochemical	ADJ
admet-2766	13	10	biosensor	biosensor	NOUN
admet-2766	13	11	exhibits	exhibit	VERB
admet-2766	13	12	high	high	ADJ
admet-2766	13	13	sensitivity	sensitivity	NOUN
admet-2766	13	14	and	and	CCONJ
admet-2766	13	15	specificity	specificity	NOUN
admet-2766	13	16	for	for	ADP
admet-2766	13	17	the	the	DET
admet-2766	13	18	detection	detection	NOUN
admet-2766	13	19	katg	katg	PROPN
admet-2766	13	20	mutation	mutation	NOUN
admet-2766	13	21	,	,	PUNCT
admet-2766	13	22	offering	offer	VERB
admet-2766	13	23	a	a	DET
admet-2766	13	24	promising	promising	ADJ
admet-2766	13	25	platform	platform	NOUN
admet-2766	13	26	for	for	ADP
admet-2766	13	27	rapid	rapid	ADJ
admet-2766	13	28	mdr	mdr	PROPN
admet-2766	13	29	-	-	NOUN
admet-2766	13	30	tb	tb	ADP
admet-2766	13	31	diagnostics	diagnostic	NOUN
admet-2766	13	32	.	.	PUNCT
admet-2766	14	1	©	©	PROPN
admet-2766	14	2	2025	2025	NUM
admet-2766	14	3	by	by	ADP
admet-2766	14	4	the	the	DET
admet-2766	14	5	authors	author	NOUN
admet-2766	14	6	.	.	PUNCT
admet-2766	15	1	this	this	DET
admet-2766	15	2	article	article	NOUN
admet-2766	15	3	is	be	AUX
admet-2766	15	4	an	an	DET
admet-2766	15	5	open	open	ADJ
admet-2766	15	6	-	-	PUNCT
admet-2766	15	7	access	access	NOUN
admet-2766	15	8	article	article	NOUN
admet-2766	15	9	distributed	distribute	VERB
admet-2766	15	10	under	under	ADP
admet-2766	15	11	the	the	DET
admet-2766	15	12	terms	term	NOUN
admet-2766	15	13	and	and	CCONJ
admet-2766	15	14	conditions	condition	NOUN
admet-2766	15	15	of	of	ADP
admet-2766	15	16	the	the	DET
admet-2766	15	17	creative	creative	ADJ
admet-2766	15	18	commons	common	NOUN
admet-2766	15	19	attribution	attribution	NOUN
admet-2766	15	20	license	license	NOUN
admet-2766	15	21	(	(	PUNCT
admet-2766	15	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2766	15	23	)	)	PUNCT
admet-2766	15	24	.	.	PUNCT
admet-2766	16	1	keywords	keyword	NOUN
admet-2766	16	2	electrochemistry	electrochemistry	NOUN
admet-2766	16	3	;	;	PUNCT
admet-2766	16	4	guide	guide	VERB
admet-2766	16	5	rna	rna	PROPN
admet-2766	16	6	;	;	PUNCT
admet-2766	16	7	ferrocene	ferrocene	NOUN
admet-2766	16	8	signal	signal	NOUN
admet-2766	16	9	;	;	PUNCT
admet-2766	16	10	drug	drug	NOUN
admet-2766	16	11	-	-	PUNCT
admet-2766	16	12	resistant	resistant	ADJ
admet-2766	16	13	tuberculosis	tuberculosis	NOUN
admet-2766	16	14	introduction	introduction	NOUN
admet-2766	16	15	tuberculosis	tuberculosis	NOUN
admet-2766	16	16	(	(	PUNCT
admet-2766	16	17	tb	tb	NOUN
admet-2766	16	18	)	)	PUNCT
admet-2766	16	19	remains	remain	VERB
admet-2766	16	20	the	the	DET
admet-2766	16	21	second	second	ADJ
admet-2766	16	22	leading	leading	ADJ
admet-2766	16	23	cause	cause	NOUN
admet-2766	16	24	of	of	ADP
admet-2766	16	25	infectious	infectious	ADJ
admet-2766	16	26	disease	disease	NOUN
admet-2766	16	27	-	-	PUNCT
admet-2766	16	28	related	relate	VERB
admet-2766	16	29	mortality	mortality	NOUN
admet-2766	16	30	worldwide	worldwide	ADV
admet-2766	16	31	,	,	PUNCT
admet-2766	16	32	responsible	responsible	ADJ
admet-2766	16	33	for	for	ADP
admet-2766	16	34	nearly	nearly	ADV
admet-2766	16	35	twice	twice	DET
admet-2766	16	36	as	as	ADV
admet-2766	16	37	many	many	ADJ
admet-2766	16	38	deaths	death	NOUN
admet-2766	16	39	as	as	ADP
admet-2766	16	40	hiv	hiv	PROPN
admet-2766	16	41	/	/	SYM
admet-2766	16	42	aids	aids	PROPN
admet-2766	16	43	.	.	PUNCT
admet-2766	17	1	over	over	ADP
admet-2766	17	2	10	10	NUM
admet-2766	17	3	million	million	NUM
admet-2766	17	4	people	people	NOUN
admet-2766	17	5	are	be	AUX
admet-2766	17	6	affected	affect	VERB
admet-2766	17	7	annually	annually	ADV
admet-2766	17	8	,	,	PUNCT
admet-2766	17	9	and	and	CCONJ
admet-2766	17	10	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	17	11	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	17	12	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-2766	17	13	mailto:yeni.w.hartati@unpad.ac.id	mailto:yeni.w.hartati@unpad.ac.id	PROPN
admet-2766	17	14	mailto:irkham@unpad.ac.id	mailto:irkham@unpad.ac.id	PROPN
admet-2766	17	15	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2766	17	16	d.	d.	PROPN
admet-2766	17	17	a.	a.	PROPN
admet-2766	17	18	wulandari	wulandari	PROPN
admet-2766	17	19	et	et	PROPN
admet-2766	17	20	al	al	PROPN
admet-2766	17	21	.	.	PROPN
admet-2766	17	22	admet	admet	PROPN
admet-2766	17	23	&	&	CCONJ
admet-2766	17	24	dmpk	dmpk	PROPN
admet-2766	17	25	13(3	13(3	NUM
admet-2766	17	26	)	)	PUNCT
admet-2766	17	27	(	(	PUNCT
admet-2766	17	28	2025	2025	NUM
admet-2766	17	29	)	)	PUNCT
admet-2766	17	30	2766	2766	NUM
admet-2766	17	31	2	2	NUM
admet-2766	17	32	since	since	SCONJ
admet-2766	17	33	2021	2021	NUM
admet-2766	17	34	,	,	PUNCT
admet-2766	17	35	tb	tb	ADP
admet-2766	17	36	incidence	incidence	NOUN
admet-2766	17	37	has	have	AUX
admet-2766	17	38	continued	continue	VERB
admet-2766	17	39	to	to	PART
admet-2766	17	40	rise	rise	VERB
admet-2766	17	41	[	[	X
admet-2766	17	42	1	1	NUM
admet-2766	17	43	]	]	PUNCT
admet-2766	17	44	.	.	PUNCT
admet-2766	18	1	tb	tb	X
admet-2766	18	2	is	be	AUX
admet-2766	18	3	caused	cause	VERB
admet-2766	18	4	by	by	ADP
admet-2766	18	5	the	the	DET
admet-2766	18	6	aerobic	aerobic	ADJ
admet-2766	18	7	bacterium	bacterium	NOUN
admet-2766	18	8	mycobacterium	mycobacterium	NOUN
admet-2766	18	9	tuberculosis	tuberculosis	NOUN
admet-2766	18	10	(	(	PUNCT
admet-2766	18	11	mtb	mtb	NOUN
admet-2766	18	12	)	)	PUNCT
admet-2766	18	13	,	,	PUNCT
admet-2766	18	14	which	which	PRON
admet-2766	18	15	commonly	commonly	ADV
admet-2766	18	16	infects	infect	VERB
admet-2766	18	17	oxygen	oxygen	NOUN
admet-2766	18	18	-	-	PUNCT
admet-2766	18	19	rich	rich	ADJ
admet-2766	18	20	tissues	tissue	NOUN
admet-2766	18	21	[	[	X
admet-2766	18	22	2,3	2,3	NUM
admet-2766	18	23	]	]	PUNCT
admet-2766	18	24	.	.	PUNCT
admet-2766	19	1	the	the	DET
admet-2766	19	2	emergence	emergence	NOUN
admet-2766	19	3	of	of	ADP
admet-2766	19	4	drug	drug	NOUN
admet-2766	19	5	-	-	PUNCT
admet-2766	19	6	resistant	resistant	ADJ
admet-2766	19	7	tb	tb	ADP
admet-2766	19	8	strains	strain	NOUN
admet-2766	19	9	,	,	PUNCT
admet-2766	19	10	particularly	particularly	ADV
admet-2766	19	11	multidrug	multidrug	NOUN
admet-2766	19	12	-	-	PUNCT
admet-2766	19	13	resistant	resistant	ADJ
admet-2766	19	14	tb	tb	X
admet-2766	19	15	(	(	PUNCT
admet-2766	19	16	mdr	mdr	PROPN
admet-2766	19	17	-	-	PROPN
admet-2766	19	18	tb	tb	NOUN
admet-2766	19	19	)	)	PUNCT
admet-2766	19	20	,	,	PUNCT
admet-2766	19	21	poses	pose	VERB
admet-2766	19	22	a	a	DET
admet-2766	19	23	significant	significant	ADJ
admet-2766	19	24	challenge	challenge	NOUN
admet-2766	19	25	to	to	ADP
admet-2766	19	26	global	global	ADJ
admet-2766	19	27	tb	tb	ADP
admet-2766	19	28	control	control	NOUN
admet-2766	19	29	efforts	effort	NOUN
admet-2766	19	30	[	[	X
admet-2766	19	31	4	4	NUM
admet-2766	19	32	-	-	SYM
admet-2766	19	33	6	6	NUM
admet-2766	19	34	]	]	PUNCT
admet-2766	19	35	.	.	PUNCT
admet-2766	20	1	these	these	DET
admet-2766	20	2	strains	strain	NOUN
admet-2766	20	3	often	often	ADV
admet-2766	20	4	harbour	harbour	VERB
admet-2766	20	5	genetic	genetic	ADJ
admet-2766	20	6	mutations	mutation	NOUN
admet-2766	20	7	that	that	PRON
admet-2766	20	8	allow	allow	VERB
admet-2766	20	9	them	they	PRON
admet-2766	20	10	to	to	PART
admet-2766	20	11	evade	evade	VERB
admet-2766	20	12	the	the	DET
admet-2766	20	13	effects	effect	NOUN
admet-2766	20	14	of	of	ADP
admet-2766	20	15	commonly	commonly	ADV
admet-2766	20	16	used	use	VERB
admet-2766	20	17	drugs	drug	NOUN
admet-2766	20	18	[	[	X
admet-2766	20	19	7	7	NUM
admet-2766	20	20	]	]	PUNCT
admet-2766	20	21	.	.	PUNCT
admet-2766	21	1	one	one	NUM
admet-2766	21	2	of	of	ADP
admet-2766	21	3	the	the	DET
admet-2766	21	4	most	most	ADV
admet-2766	21	5	critical	critical	ADJ
admet-2766	21	6	drugs	drug	NOUN
admet-2766	21	7	in	in	ADP
admet-2766	21	8	tb	tb	ADP
admet-2766	21	9	treatment	treatment	NOUN
admet-2766	21	10	is	be	AUX
admet-2766	21	11	isoniazid	isoniazid	NOUN
admet-2766	21	12	(	(	PUNCT
admet-2766	21	13	inh	inh	PROPN
admet-2766	21	14	)	)	PUNCT
admet-2766	21	15	.	.	PUNCT
admet-2766	22	1	resistance	resistance	NOUN
admet-2766	22	2	to	to	ADP
admet-2766	22	3	inh	inh	PROPN
admet-2766	22	4	,	,	PUNCT
admet-2766	22	5	often	often	ADV
admet-2766	22	6	due	due	ADP
admet-2766	22	7	to	to	ADP
admet-2766	22	8	mutations	mutation	NOUN
admet-2766	22	9	in	in	ADP
admet-2766	22	10	the	the	DET
admet-2766	22	11	katg	katg	PROPN
admet-2766	22	12	gene	gene	NOUN
admet-2766	22	13	,	,	PUNCT
admet-2766	22	14	is	be	AUX
admet-2766	22	15	a	a	DET
admet-2766	22	16	major	major	ADJ
admet-2766	22	17	contributor	contributor	NOUN
admet-2766	22	18	to	to	ADP
admet-2766	22	19	treatment	treatment	NOUN
admet-2766	22	20	failure	failure	NOUN
admet-2766	22	21	[	[	X
admet-2766	22	22	8	8	NUM
admet-2766	22	23	-	-	SYM
admet-2766	22	24	11	11	NUM
admet-2766	22	25	]	]	PUNCT
admet-2766	22	26	.	.	PUNCT
admet-2766	23	1	traditional	traditional	ADJ
admet-2766	23	2	diagnostic	diagnostic	ADJ
admet-2766	23	3	methods	method	NOUN
admet-2766	23	4	,	,	PUNCT
admet-2766	23	5	such	such	ADJ
admet-2766	23	6	as	as	ADP
admet-2766	23	7	bacterial	bacterial	ADJ
admet-2766	23	8	culture	culture	NOUN
admet-2766	23	9	,	,	PUNCT
admet-2766	23	10	are	be	AUX
admet-2766	23	11	time	time	NOUN
admet-2766	23	12	-	-	PUNCT
admet-2766	23	13	consuming	consume	VERB
admet-2766	23	14	and	and	CCONJ
admet-2766	23	15	lack	lack	NOUN
admet-2766	23	16	sensitivity	sensitivity	NOUN
admet-2766	23	17	and	and	CCONJ
admet-2766	23	18	specificity	specificity	NOUN
admet-2766	23	19	[	[	X
admet-2766	23	20	12,13	12,13	NUM
admet-2766	23	21	]	]	PUNCT
admet-2766	23	22	.	.	PUNCT
admet-2766	24	1	in	in	ADP
admet-2766	24	2	2010	2010	NUM
admet-2766	24	3	,	,	PUNCT
admet-2766	24	4	the	the	DET
admet-2766	24	5	world	world	PROPN
admet-2766	24	6	health	health	NOUN
admet-2766	24	7	organization	organization	NOUN
admet-2766	24	8	(	(	PUNCT
admet-2766	24	9	who	who	PRON
admet-2766	24	10	)	)	PUNCT
admet-2766	24	11	recommended	recommend	VERB
admet-2766	24	12	the	the	DET
admet-2766	24	13	use	use	NOUN
admet-2766	24	14	of	of	ADP
admet-2766	24	15	genexpert	genexpert	ADJ
admet-2766	24	16	as	as	ADP
admet-2766	24	17	a	a	DET
admet-2766	24	18	diagnostic	diagnostic	ADJ
admet-2766	24	19	tool	tool	NOUN
admet-2766	24	20	for	for	ADP
admet-2766	24	21	early	early	ADJ
admet-2766	24	22	detection	detection	NOUN
admet-2766	24	23	of	of	ADP
admet-2766	24	24	mdr	mdr	PROPN
admet-2766	24	25	-	-	PROPN
admet-2766	24	26	tb	tb	PROPN
admet-2766	24	27	,	,	PUNCT
admet-2766	24	28	replacing	replace	VERB
admet-2766	24	29	traditional	traditional	ADJ
admet-2766	24	30	smear	smear	NOUN
admet-2766	24	31	microscopy	microscopy	NOUN
admet-2766	24	32	[	[	X
admet-2766	24	33	8	8	NUM
admet-2766	24	34	]	]	PUNCT
admet-2766	24	35	.	.	PUNCT
admet-2766	25	1	while	while	SCONJ
admet-2766	25	2	genexpert	genexpert	PROPN
admet-2766	25	3	is	be	AUX
admet-2766	25	4	effective	effective	ADJ
admet-2766	25	5	in	in	ADP
admet-2766	25	6	detecting	detect	VERB
admet-2766	25	7	rifampicin	rifampicin	VERB
admet-2766	25	8	resistance	resistance	NOUN
admet-2766	25	9	(	(	PUNCT
admet-2766	25	10	rif	rif	NOUN
admet-2766	25	11	-	-	PUNCT
admet-2766	25	12	r	r	NOUN
admet-2766	25	13	)	)	PUNCT
admet-2766	25	14	,	,	PUNCT
admet-2766	25	15	it	it	PRON
admet-2766	25	16	can	can	AUX
admet-2766	25	17	not	not	PART
admet-2766	25	18	identify	identify	VERB
admet-2766	25	19	resistance	resistance	NOUN
admet-2766	25	20	to	to	ADP
admet-2766	25	21	isoniazid	isoniazid	PROPN
admet-2766	25	22	(	(	PUNCT
admet-2766	25	23	inh	inh	PROPN
admet-2766	25	24	)	)	PUNCT
admet-2766	25	25	,	,	PUNCT
admet-2766	25	26	a	a	DET
admet-2766	25	27	key	key	ADJ
admet-2766	25	28	drug	drug	NOUN
admet-2766	25	29	in	in	ADP
admet-2766	25	30	tb	tb	ADP
admet-2766	25	31	treatment	treatment	NOUN
admet-2766	25	32	[	[	X
admet-2766	25	33	14	14	NUM
admet-2766	25	34	]	]	PUNCT
admet-2766	25	35	.	.	PUNCT
admet-2766	26	1	therefore	therefore	ADV
admet-2766	26	2	,	,	PUNCT
admet-2766	26	3	there	there	PRON
admet-2766	26	4	is	be	VERB
admet-2766	26	5	a	a	DET
admet-2766	26	6	pressing	press	VERB
admet-2766	26	7	need	need	NOUN
admet-2766	26	8	for	for	ADP
admet-2766	26	9	rapid	rapid	ADJ
admet-2766	26	10	,	,	PUNCT
admet-2766	26	11	sensitive	sensitive	ADJ
admet-2766	26	12	,	,	PUNCT
admet-2766	26	13	and	and	CCONJ
admet-2766	26	14	specific	specific	ADJ
admet-2766	26	15	diagnostic	diagnostic	ADJ
admet-2766	26	16	tools	tool	NOUN
admet-2766	26	17	to	to	PART
admet-2766	26	18	detect	detect	VERB
admet-2766	26	19	katg	katg	NOUN
admet-2766	26	20	mutations	mutation	NOUN
admet-2766	26	21	associated	associate	VERB
admet-2766	26	22	with	with	ADP
admet-2766	26	23	inh	inh	PROPN
admet-2766	26	24	resistance	resistance	NOUN
admet-2766	26	25	,	,	PUNCT
admet-2766	26	26	enabling	enable	VERB
admet-2766	26	27	more	more	ADV
admet-2766	26	28	accurate	accurate	ADJ
admet-2766	26	29	mdr	mdr	NOUN
admet-2766	26	30	-	-	NOUN
admet-2766	26	31	tb	tb	ADP
admet-2766	26	32	diagnosis	diagnosis	NOUN
admet-2766	26	33	and	and	CCONJ
admet-2766	26	34	effective	effective	ADJ
admet-2766	26	35	patient	patient	ADJ
admet-2766	26	36	management	management	NOUN
admet-2766	26	37	.	.	PUNCT
admet-2766	27	1	crispr	crispr	PROPN
admet-2766	27	2	/	/	SYM
admet-2766	27	3	cas9	cas9	NOUN
admet-2766	27	4	-	-	PUNCT
admet-2766	27	5	based	base	VERB
admet-2766	27	6	molecular	molecular	ADJ
admet-2766	27	7	diagnostics	diagnostic	NOUN
admet-2766	27	8	have	have	AUX
admet-2766	27	9	emerged	emerge	VERB
admet-2766	27	10	as	as	ADP
admet-2766	27	11	promising	promising	ADJ
admet-2766	27	12	tools	tool	NOUN
admet-2766	27	13	for	for	ADP
admet-2766	27	14	rapid	rapid	ADJ
admet-2766	27	15	and	and	CCONJ
admet-2766	27	16	precise	precise	ADJ
admet-2766	27	17	detection	detection	NOUN
admet-2766	27	18	of	of	ADP
admet-2766	27	19	nucleic	nucleic	ADJ
admet-2766	27	20	acid	acid	NOUN
admet-2766	27	21	mutations	mutation	NOUN
admet-2766	27	22	and	and	CCONJ
admet-2766	27	23	for	for	ADP
admet-2766	27	24	point	point	NOUN
admet-2766	27	25	-	-	PUNCT
admet-2766	27	26	of	of	ADP
admet-2766	27	27	-	-	PUNCT
admet-2766	27	28	care	care	NOUN
admet-2766	27	29	(	(	PUNCT
admet-2766	27	30	poc	poc	NOUN
admet-2766	27	31	)	)	PUNCT
admet-2766	27	32	applications	application	NOUN
admet-2766	27	33	[	[	PUNCT
admet-2766	27	34	15	15	NUM
admet-2766	27	35	-	-	SYM
admet-2766	27	36	18	18	NUM
admet-2766	27	37	]	]	PUNCT
admet-2766	27	38	.	.	PUNCT
admet-2766	28	1	the	the	DET
admet-2766	28	2	technology	technology	NOUN
admet-2766	28	3	is	be	AUX
admet-2766	28	4	also	also	ADV
admet-2766	28	5	highly	highly	ADV
admet-2766	28	6	sensitive	sensitive	ADJ
admet-2766	28	7	,	,	PUNCT
admet-2766	28	8	enabling	enable	VERB
admet-2766	28	9	the	the	DET
admet-2766	28	10	detection	detection	NOUN
admet-2766	28	11	of	of	ADP
admet-2766	28	12	low	low	ADJ
admet-2766	28	13	levels	level	NOUN
admet-2766	28	14	of	of	ADP
admet-2766	28	15	nucleic	nucleic	ADJ
admet-2766	28	16	acids	acid	NOUN
admet-2766	28	17	,	,	PUNCT
admet-2766	28	18	and	and	CCONJ
admet-2766	28	19	provides	provide	VERB
admet-2766	28	20	rapid	rapid	ADJ
admet-2766	28	21	results	result	NOUN
admet-2766	28	22	,	,	PUNCT
admet-2766	28	23	allowing	allow	VERB
admet-2766	28	24	for	for	ADP
admet-2766	28	25	timely	timely	ADJ
admet-2766	28	26	diagnosis	diagnosis	NOUN
admet-2766	28	27	of	of	ADP
admet-2766	28	28	infectious	infectious	ADJ
admet-2766	28	29	diseases	disease	NOUN
admet-2766	28	30	or	or	CCONJ
admet-2766	28	31	genetic	genetic	ADJ
admet-2766	28	32	disorders	disorder	NOUN
admet-2766	28	33	[	[	X
admet-2766	28	34	19	19	NUM
admet-2766	28	35	-	-	SYM
admet-2766	28	36	21	21	NUM
admet-2766	28	37	]	]	PUNCT
admet-2766	28	38	.	.	PUNCT
admet-2766	29	1	the	the	DET
admet-2766	29	2	crispr	crispr	ADJ
admet-2766	29	3	system	system	NOUN
admet-2766	29	4	consists	consist	VERB
admet-2766	29	5	of	of	ADP
admet-2766	29	6	two	two	NUM
admet-2766	29	7	main	main	ADJ
admet-2766	29	8	components	component	NOUN
admet-2766	29	9	:	:	PUNCT
admet-2766	29	10	the	the	DET
admet-2766	29	11	cas	cas	PROPN
admet-2766	29	12	protein	protein	NOUN
admet-2766	29	13	,	,	PUNCT
admet-2766	29	14	which	which	PRON
admet-2766	29	15	acts	act	VERB
admet-2766	29	16	as	as	ADP
admet-2766	29	17	an	an	DET
admet-2766	29	18	endonuclease	endonuclease	NOUN
admet-2766	29	19	,	,	PUNCT
admet-2766	29	20	and	and	CCONJ
admet-2766	29	21	the	the	DET
admet-2766	29	22	guide	guide	NOUN
admet-2766	29	23	rna	rna	NOUN
admet-2766	29	24	(	(	PUNCT
admet-2766	29	25	grna	grna	NOUN
admet-2766	29	26	)	)	PUNCT
admet-2766	29	27	,	,	PUNCT
admet-2766	29	28	which	which	PRON
admet-2766	29	29	directs	direct	VERB
admet-2766	29	30	cas	cas	PROPN
admet-2766	29	31	to	to	ADP
admet-2766	29	32	the	the	DET
admet-2766	29	33	specific	specific	ADJ
admet-2766	29	34	sequence	sequence	NOUN
admet-2766	29	35	.	.	PUNCT
admet-2766	30	1	the	the	DET
admet-2766	30	2	cas	cas	PROPN
admet-2766	30	3	protein	protein	NOUN
admet-2766	30	4	and	and	CCONJ
admet-2766	30	5	grna	grna	NOUN
admet-2766	30	6	combine	combine	NOUN
admet-2766	30	7	to	to	PART
admet-2766	30	8	form	form	VERB
admet-2766	30	9	a	a	DET
admet-2766	30	10	ribonucleoprotein	ribonucleoprotein	NOUN
admet-2766	30	11	(	(	PUNCT
admet-2766	30	12	rnp	rnp	PROPN
admet-2766	30	13	)	)	PUNCT
admet-2766	30	14	complex	complex	NOUN
admet-2766	30	15	,	,	PUNCT
admet-2766	30	16	which	which	PRON
admet-2766	30	17	becomes	become	VERB
admet-2766	30	18	active	active	ADJ
admet-2766	30	19	when	when	SCONJ
admet-2766	30	20	it	it	PRON
admet-2766	30	21	encounters	encounter	VERB
admet-2766	30	22	target	target	VERB
admet-2766	30	23	dna	dna	PROPN
admet-2766	30	24	complementary	complementary	ADJ
admet-2766	30	25	to	to	ADP
admet-2766	30	26	the	the	DET
admet-2766	30	27	grna	grna	NOUN
admet-2766	30	28	and	and	CCONJ
admet-2766	30	29	recognized	recognize	VERB
admet-2766	30	30	by	by	ADP
admet-2766	30	31	the	the	DET
admet-2766	30	32	protospacer	protospacer	NOUN
admet-2766	30	33	adjacent	adjacent	ADJ
admet-2766	30	34	motif	motif	NOUN
admet-2766	30	35	(	(	PUNCT
admet-2766	30	36	pam	pam	NOUN
admet-2766	30	37	)	)	PUNCT
admet-2766	30	38	sequence	sequence	NOUN
admet-2766	30	39	.	.	PUNCT
admet-2766	31	1	the	the	DET
admet-2766	31	2	cutting	cut	VERB
admet-2766	31	3	efficiency	efficiency	NOUN
admet-2766	31	4	of	of	ADP
admet-2766	31	5	the	the	DET
admet-2766	31	6	crispr	crispr	ADJ
admet-2766	31	7	/	/	SYM
admet-2766	31	8	cas	cas	NOUN
admet-2766	31	9	system	system	NOUN
admet-2766	31	10	is	be	AUX
admet-2766	31	11	influenced	influence	VERB
admet-2766	31	12	by	by	ADP
admet-2766	31	13	factors	factor	NOUN
admet-2766	31	14	including	include	VERB
admet-2766	31	15	the	the	DET
admet-2766	31	16	design	design	NOUN
admet-2766	31	17	of	of	ADP
admet-2766	31	18	the	the	DET
admet-2766	31	19	grna	grna	NOUN
admet-2766	31	20	specific	specific	ADJ
admet-2766	31	21	to	to	ADP
admet-2766	31	22	the	the	DET
admet-2766	31	23	target	target	NOUN
admet-2766	31	24	dna	dna	NOUN
admet-2766	31	25	sequence	sequence	NOUN
admet-2766	31	26	[	[	X
admet-2766	31	27	22	22	NUM
admet-2766	31	28	]	]	PUNCT
admet-2766	31	29	.	.	PUNCT
admet-2766	32	1	the	the	DET
admet-2766	32	2	single	single	ADJ
admet-2766	32	3	-	-	PUNCT
admet-2766	32	4	guide	guide	NOUN
admet-2766	32	5	rna	rna	NOUN
admet-2766	32	6	(	(	PUNCT
admet-2766	32	7	sgrna	sgrna	PROPN
admet-2766	32	8	)	)	PUNCT
admet-2766	32	9	is	be	AUX
admet-2766	32	10	a	a	DET
admet-2766	32	11	modified	modify	VERB
admet-2766	32	12	version	version	NOUN
admet-2766	32	13	of	of	ADP
admet-2766	32	14	the	the	DET
admet-2766	32	15	naturally	naturally	ADV
admet-2766	32	16	occurring	occur	VERB
admet-2766	32	17	two	two	NUM
admet-2766	32	18	-	-	PUNCT
admet-2766	32	19	part	part	NOUN
admet-2766	32	20	grna	grna	NOUN
admet-2766	32	21	complex	complex	NOUN
admet-2766	32	22	,	,	PUNCT
admet-2766	32	23	combined	combine	VERB
admet-2766	32	24	into	into	ADP
admet-2766	32	25	an	an	DET
admet-2766	32	26	rna	rna	NOUN
admet-2766	32	27	sequence	sequence	NOUN
admet-2766	32	28	.	.	PUNCT
admet-2766	33	1	it	it	PRON
admet-2766	33	2	contains	contain	VERB
admet-2766	33	3	the	the	DET
admet-2766	33	4	crrna	crrna	NOUN
admet-2766	33	5	,	,	PUNCT
admet-2766	33	6	which	which	PRON
admet-2766	33	7	directs	direct	VERB
admet-2766	33	8	cas9	cas9	NOUN
admet-2766	33	9	to	to	ADP
admet-2766	33	10	the	the	DET
admet-2766	33	11	target	target	NOUN
admet-2766	33	12	site	site	NOUN
admet-2766	33	13	,	,	PUNCT
admet-2766	33	14	and	and	CCONJ
admet-2766	33	15	the	the	DET
admet-2766	33	16	tracrrna	tracrrna	NOUN
admet-2766	33	17	,	,	PUNCT
admet-2766	33	18	which	which	PRON
admet-2766	33	19	forms	form	VERB
admet-2766	33	20	a	a	DET
admet-2766	33	21	scaffold	scaffold	NOUN
admet-2766	33	22	for	for	ADP
admet-2766	33	23	cas9	cas9	NOUN
admet-2766	33	24	binding	bind	VERB
admet-2766	33	25	.	.	PUNCT
admet-2766	34	1	precise	precise	ADJ
admet-2766	34	2	targeting	targeting	NOUN
admet-2766	34	3	is	be	AUX
admet-2766	34	4	achieved	achieve	VERB
admet-2766	34	5	by	by	ADP
admet-2766	34	6	synthesizing	synthesize	VERB
admet-2766	34	7	an	an	DET
admet-2766	34	8	rna	rna	NOUN
admet-2766	34	9	molecule	molecule	NOUN
admet-2766	34	10	that	that	PRON
admet-2766	34	11	consists	consist	VERB
admet-2766	34	12	of	of	ADP
admet-2766	34	13	a	a	DET
admet-2766	34	14	grna	grna	NOUN
admet-2766	34	15	complementary	complementary	ADJ
admet-2766	34	16	to	to	ADP
admet-2766	34	17	the	the	DET
admet-2766	34	18	target	target	NOUN
admet-2766	34	19	strand	strand	NOUN
admet-2766	34	20	,	,	PUNCT
admet-2766	34	21	along	along	ADP
admet-2766	34	22	with	with	ADP
admet-2766	34	23	a	a	DET
admet-2766	34	24	constant	constant	ADJ
admet-2766	34	25	tracrrna	tracrrna	NOUN
admet-2766	35	1	[	[	X
admet-2766	35	2	23,24	23,24	ADP
admet-2766	35	3	]	]	PUNCT
admet-2766	35	4	.	.	PUNCT
admet-2766	36	1	an	an	DET
admet-2766	36	2	essential	essential	ADJ
admet-2766	36	3	characteristic	characteristic	NOUN
admet-2766	36	4	of	of	ADP
admet-2766	36	5	the	the	DET
admet-2766	36	6	crispr	crispr	ADJ
admet-2766	36	7	/	/	SYM
admet-2766	36	8	cas	cas	NOUN
admet-2766	36	9	system	system	NOUN
admet-2766	36	10	is	be	AUX
admet-2766	36	11	the	the	DET
admet-2766	36	12	pam	pam	NOUN
admet-2766	36	13	,	,	PUNCT
admet-2766	36	14	a	a	DET
admet-2766	36	15	conserved	conserve	VERB
admet-2766	36	16	dna	dna	NOUN
admet-2766	36	17	sequence	sequence	NOUN
admet-2766	36	18	adjacent	adjacent	ADJ
admet-2766	36	19	to	to	ADP
admet-2766	36	20	the	the	DET
admet-2766	36	21	target	target	NOUN
admet-2766	36	22	site	site	NOUN
admet-2766	36	23	that	that	PRON
admet-2766	36	24	is	be	AUX
admet-2766	36	25	crispr	crispr	NOUN
admet-2766	36	26	-	-	PUNCT
admet-2766	36	27	dependent	dependent	ADJ
admet-2766	36	28	[	[	X
admet-2766	36	29	25	25	NUM
admet-2766	36	30	]	]	PUNCT
admet-2766	36	31	.	.	PUNCT
admet-2766	37	1	recent	recent	ADJ
admet-2766	37	2	advancements	advancement	NOUN
admet-2766	37	3	have	have	AUX
admet-2766	37	4	integrated	integrate	VERB
admet-2766	37	5	crispr	crispr	ADJ
admet-2766	37	6	/	/	SYM
admet-2766	37	7	cas9	cas9	NOUN
admet-2766	37	8	with	with	ADP
admet-2766	37	9	electrochemical	electrochemical	ADJ
admet-2766	37	10	biosensors	biosensor	NOUN
admet-2766	37	11	to	to	PART
admet-2766	37	12	create	create	VERB
admet-2766	37	13	sensitive	sensitive	ADJ
admet-2766	37	14	,	,	PUNCT
admet-2766	37	15	specific	specific	ADJ
admet-2766	37	16	,	,	PUNCT
admet-2766	37	17	and	and	CCONJ
admet-2766	37	18	rapid	rapid	ADJ
admet-2766	37	19	platforms	platform	NOUN
admet-2766	37	20	for	for	ADP
admet-2766	37	21	diagnostics	diagnostic	NOUN
admet-2766	37	22	.	.	PUNCT
admet-2766	38	1	when	when	SCONJ
admet-2766	38	2	combined	combine	VERB
admet-2766	38	3	with	with	ADP
admet-2766	38	4	the	the	DET
admet-2766	38	5	precision	precision	NOUN
admet-2766	38	6	targeting	target	VERB
admet-2766	38	7	capability	capability	NOUN
admet-2766	38	8	of	of	ADP
admet-2766	38	9	crispr	crispr	ADJ
admet-2766	38	10	/	/	SYM
admet-2766	38	11	cas9	cas9	NOUN
admet-2766	38	12	,	,	PUNCT
admet-2766	38	13	electrochemical	electrochemical	ADJ
admet-2766	38	14	biosensors	biosensor	NOUN
admet-2766	38	15	can	can	AUX
admet-2766	38	16	be	be	AUX
admet-2766	38	17	transformed	transform	VERB
admet-2766	38	18	into	into	ADP
admet-2766	38	19	programmable	programmable	ADJ
admet-2766	38	20	platforms	platform	NOUN
admet-2766	38	21	capable	capable	ADJ
admet-2766	38	22	of	of	ADP
admet-2766	38	23	detecting	detect	VERB
admet-2766	38	24	specific	specific	ADJ
admet-2766	38	25	genetic	genetic	ADJ
admet-2766	38	26	mutations	mutation	NOUN
admet-2766	38	27	.	.	PUNCT
admet-2766	39	1	the	the	DET
admet-2766	39	2	crispr	crispr	ADJ
admet-2766	39	3	/	/	SYM
admet-2766	39	4	cas9	cas9	NOUN
admet-2766	39	5	system	system	NOUN
admet-2766	39	6	can	can	AUX
admet-2766	39	7	be	be	AUX
admet-2766	39	8	programmed	program	VERB
admet-2766	39	9	with	with	ADP
admet-2766	39	10	a	a	DET
admet-2766	39	11	guide	guide	NOUN
admet-2766	39	12	rna	rna	NOUN
admet-2766	39	13	(	(	PUNCT
admet-2766	39	14	grna	grna	NOUN
admet-2766	39	15	)	)	PUNCT
admet-2766	39	16	to	to	PART
admet-2766	39	17	recognize	recognize	VERB
admet-2766	39	18	a	a	DET
admet-2766	39	19	precise	precise	ADJ
admet-2766	39	20	dna	dna	NOUN
admet-2766	39	21	sequence	sequence	NOUN
admet-2766	39	22	adjacent	adjacent	ADJ
admet-2766	39	23	to	to	ADP
admet-2766	39	24	a	a	DET
admet-2766	39	25	protospacer	protospacer	NOUN
admet-2766	39	26	adjacent	adjacent	ADJ
admet-2766	39	27	motif	motif	NOUN
admet-2766	39	28	(	(	PUNCT
admet-2766	39	29	pam	pam	NOUN
admet-2766	39	30	)	)	PUNCT
admet-2766	39	31	,	,	PUNCT
admet-2766	39	32	resulting	result	VERB
admet-2766	39	33	in	in	ADP
admet-2766	39	34	a	a	DET
admet-2766	39	35	site	site	NOUN
admet-2766	39	36	-	-	PUNCT
admet-2766	39	37	specific	specific	ADJ
admet-2766	39	38	cleavage	cleavage	NOUN
admet-2766	39	39	event	event	NOUN
admet-2766	39	40	.	.	PUNCT
admet-2766	40	1	in	in	ADP
admet-2766	40	2	a	a	DET
admet-2766	40	3	biosensor	biosensor	NOUN
admet-2766	40	4	context	context	NOUN
admet-2766	40	5	,	,	PUNCT
admet-2766	40	6	this	this	DET
admet-2766	40	7	cleavage	cleavage	NOUN
admet-2766	40	8	can	can	AUX
admet-2766	40	9	be	be	AUX
admet-2766	40	10	transduced	transduce	VERB
admet-2766	40	11	into	into	ADP
admet-2766	40	12	an	an	DET
admet-2766	40	13	electrochemical	electrochemical	ADJ
admet-2766	40	14	signal	signal	NOUN
admet-2766	40	15	via	via	ADP
admet-2766	40	16	redoxactive	redoxactive	ADJ
admet-2766	40	17	labels	label	NOUN
admet-2766	40	18	(	(	PUNCT
admet-2766	40	19	e.g.	e.g.	ADV
admet-2766	40	20	ferrocene	ferrocene	NOUN
admet-2766	40	21	,	,	PUNCT
admet-2766	40	22	methylene	methylene	NOUN
admet-2766	40	23	blue	blue	NOUN
admet-2766	40	24	)	)	PUNCT
admet-2766	40	25	or	or	CCONJ
admet-2766	40	26	changes	change	NOUN
admet-2766	40	27	in	in	ADP
admet-2766	40	28	conductivity	conductivity	NOUN
admet-2766	40	29	at	at	ADP
admet-2766	40	30	the	the	DET
admet-2766	40	31	electrode	electrode	NOUN
admet-2766	40	32	interface	interface	NOUN
admet-2766	40	33	[	[	X
admet-2766	40	34	26	26	NUM
admet-2766	40	35	-	-	SYM
admet-2766	40	36	28	28	NUM
admet-2766	40	37	]	]	PUNCT
admet-2766	40	38	.	.	PUNCT
admet-2766	41	1	in	in	ADP
admet-2766	41	2	this	this	DET
admet-2766	41	3	study	study	NOUN
admet-2766	41	4	,	,	PUNCT
admet-2766	41	5	we	we	PRON
admet-2766	41	6	developed	develop	VERB
admet-2766	41	7	a	a	DET
admet-2766	41	8	crispr	crispr	ADJ
admet-2766	41	9	/	/	SYM
admet-2766	41	10	cas9	cas9	NOUN
admet-2766	41	11	-	-	PUNCT
admet-2766	41	12	based	base	VERB
admet-2766	41	13	electrochemical	electrochemical	ADJ
admet-2766	41	14	biosensor	biosensor	NOUN
admet-2766	41	15	for	for	ADP
admet-2766	41	16	the	the	DET
admet-2766	41	17	specific	specific	ADJ
admet-2766	41	18	detection	detection	NOUN
admet-2766	41	19	of	of	ADP
admet-2766	41	20	katg	katg	PROPN
admet-2766	41	21	gene	gene	NOUN
admet-2766	41	22	mutations	mutation	NOUN
admet-2766	41	23	associated	associate	VERB
admet-2766	41	24	with	with	ADP
admet-2766	41	25	inh	inh	PROPN
admet-2766	41	26	resistance	resistance	NOUN
admet-2766	41	27	.	.	PUNCT
admet-2766	42	1	a	a	DET
admet-2766	42	2	mutation	mutation	NOUN
admet-2766	42	3	-	-	PUNCT
admet-2766	42	4	specific	specific	ADJ
admet-2766	42	5	grna	grna	NOUN
admet-2766	42	6	was	be	AUX
admet-2766	42	7	designed	design	VERB
admet-2766	42	8	using	use	VERB
admet-2766	42	9	the	the	DET
admet-2766	42	10	benchling	benchle	VERB
admet-2766	42	11	crispr	crispr	ADJ
admet-2766	42	12	tool	tool	NOUN
admet-2766	42	13	and	and	CCONJ
admet-2766	42	14	applied	apply	VERB
admet-2766	42	15	in	in	ADP
admet-2766	42	16	a	a	DET
admet-2766	42	17	biosensor	biosensor	NOUN
admet-2766	42	18	platform	platform	NOUN
admet-2766	42	19	incorporating	incorporate	VERB
admet-2766	42	20	a	a	DET
admet-2766	42	21	ferrocene	ferrocene	NOUN
admet-2766	42	22	-	-	PUNCT
admet-2766	42	23	labelled	label	VERB
admet-2766	42	24	mutant	mutant	ADJ
admet-2766	42	25	dna	dna	PROPN
admet-2766	42	26	probe	probe	NOUN
admet-2766	42	27	.	.	PUNCT
admet-2766	43	1	the	the	DET
admet-2766	43	2	biosensor	biosensor	NOUN
admet-2766	43	3	employed	employ	VERB
admet-2766	43	4	a	a	DET
admet-2766	43	5	two	two	NUM
admet-2766	43	6	-	-	PUNCT
admet-2766	43	7	step	step	NOUN
admet-2766	43	8	mechanism	mechanism	NOUN
admet-2766	43	9	(	(	PUNCT
admet-2766	43	10	figure	figure	NOUN
admet-2766	43	11	1	1	NUM
admet-2766	43	12	)	)	PUNCT
admet-2766	43	13	,	,	PUNCT
admet-2766	43	14	screen	screen	NOUN
admet-2766	43	15	-	-	PUNCT
admet-2766	43	16	printed	print	VERB
admet-2766	43	17	carbon	carbon	NOUN
admet-2766	43	18	electrodes	electrode	NOUN
admet-2766	43	19	(	(	PUNCT
admet-2766	43	20	spce	spce	NOUN
admet-2766	43	21	)	)	PUNCT
admet-2766	43	22	were	be	AUX
admet-2766	43	23	modified	modify	VERB
admet-2766	43	24	with	with	ADP
admet-2766	43	25	gold	gold	ADJ
admet-2766	43	26	nanoparticles	nanoparticle	NOUN
admet-2766	43	27	(	(	PUNCT
admet-2766	43	28	aunps	aunps	ADJ
admet-2766	43	29	)	)	PUNCT
admet-2766	43	30	and	and	CCONJ
admet-2766	43	31	functionalized	functionalize	VERB
admet-2766	43	32	via	via	ADP
admet-2766	43	33	streptavidin	streptavidin	NOUN
admet-2766	43	34	-	-	PUNCT
admet-2766	43	35	biotin	biotin	NOUN
admet-2766	43	36	interaction	interaction	NOUN
admet-2766	43	37	to	to	PART
admet-2766	43	38	immobilize	immobilize	VERB
admet-2766	43	39	the	the	DET
admet-2766	43	40	ferrocene	ferrocene	NOUN
admet-2766	43	41	-	-	PUNCT
admet-2766	43	42	labelled	label	VERB
admet-2766	43	43	probe	probe	NOUN
admet-2766	43	44	.	.	PUNCT
admet-2766	44	1	the	the	DET
admet-2766	44	2	complementary	complementary	ADJ
admet-2766	44	3	mutant	mutant	NOUN
admet-2766	44	4	dna	dna	PROPN
admet-2766	44	5	target	target	NOUN
admet-2766	44	6	hybridized	hybridize	VERB
admet-2766	44	7	with	with	ADP
admet-2766	44	8	the	the	DET
admet-2766	44	9	probe	probe	NOUN
admet-2766	44	10	and	and	CCONJ
admet-2766	44	11	was	be	AUX
admet-2766	44	12	cleaved	cleave	VERB
admet-2766	44	13	explicitly	explicitly	ADV
admet-2766	44	14	by	by	ADP
admet-2766	44	15	the	the	DET
admet-2766	44	16	cas9	cas9	NOUN
admet-2766	44	17	/	/	SYM
admet-2766	44	18	grna	grna	NOUN
admet-2766	44	19	complex	complex	NOUN
admet-2766	44	20	.	.	PUNCT
admet-2766	45	1	the	the	DET
admet-2766	45	2	cleavage	cleavage	NOUN
admet-2766	45	3	event	event	NOUN
admet-2766	45	4	disrupted	disrupt	VERB
admet-2766	45	5	the	the	DET
admet-2766	45	6	ferrocene	ferrocene	NOUN
admet-2766	45	7	signal	signal	NOUN
admet-2766	45	8	,	,	PUNCT
admet-2766	45	9	generating	generate	VERB
admet-2766	45	10	a	a	DET
admet-2766	45	11	measurable	measurable	ADJ
admet-2766	45	12	change	change	NOUN
admet-2766	45	13	in	in	ADP
admet-2766	45	14	current	current	ADJ
admet-2766	45	15	.	.	PUNCT
admet-2766	46	1	this	this	DET
admet-2766	46	2	system	system	NOUN
admet-2766	46	3	offers	offer	VERB
admet-2766	46	4	a	a	DET
admet-2766	46	5	promising	promising	ADJ
admet-2766	46	6	approach	approach	NOUN
admet-2766	46	7	for	for	ADP
admet-2766	46	8	rapid	rapid	ADJ
admet-2766	46	9	,	,	PUNCT
admet-2766	46	10	accurate	accurate	ADJ
admet-2766	46	11	,	,	PUNCT
admet-2766	46	12	and	and	CCONJ
admet-2766	46	13	field	field	NOUN
admet-2766	46	14	-	-	PUNCT
admet-2766	46	15	deployable	deployable	NOUN
admet-2766	46	16	tb	tb	ADP
admet-2766	46	17	diagnostics	diagnostic	NOUN
admet-2766	46	18	.	.	PUNCT
admet-2766	47	1	admet	admet	PROPN
admet-2766	47	2	&	&	CCONJ
admet-2766	47	3	dmpk	dmpk	PROPN
admet-2766	47	4	13(3	13(3	NUM
admet-2766	47	5	)	)	PUNCT
admet-2766	47	6	(	(	PUNCT
admet-2766	47	7	2025	2025	NUM
admet-2766	47	8	)	)	PUNCT
admet-2766	47	9	2766	2766	NUM
admet-2766	47	10	crispr	crispr	ADJ
admet-2766	47	11	/	/	SYM
admet-2766	47	12	cas9	cas9	NOUN
admet-2766	47	13	biosensor	biosensor	NOUN
admet-2766	47	14	for	for	ADP
admet-2766	47	15	the	the	DET
admet-2766	47	16	detection	detection	NOUN
admet-2766	47	17	of	of	ADP
admet-2766	47	18	katg	katg	PROPN
admet-2766	47	19	gene	gene	NOUN
admet-2766	47	20	mutations	mutation	NOUN
admet-2766	47	21	doi	doi	NOUN
admet-2766	47	22	:	:	PUNCT
admet-2766	47	23	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	ADJ
admet-2766	47	24	3	3	NUM
admet-2766	47	25	figure	figure	NOUN
admet-2766	47	26	1	1	NUM
admet-2766	47	27	.	.	PUNCT
admet-2766	47	28	biosensor	biosensor	NOUN
admet-2766	47	29	mechanism	mechanism	NOUN
admet-2766	47	30	of	of	ADP
admet-2766	47	31	(	(	PUNCT
admet-2766	47	32	a	a	X
admet-2766	47	33	)	)	PUNCT
admet-2766	47	34	spce	spce	NOUN
admet-2766	47	35	modification	modification	NOUN
admet-2766	47	36	,	,	PUNCT
admet-2766	47	37	(	(	PUNCT
admet-2766	47	38	b	b	NOUN
admet-2766	47	39	)	)	PUNCT
admet-2766	47	40	target	target	NOUN
admet-2766	47	41	recognition	recognition	NOUN
admet-2766	47	42	of	of	ADP
admet-2766	47	43	crispr	crispr	ADJ
admet-2766	47	44	/	/	SYM
admet-2766	47	45	cas9	cas9	NOUN
admet-2766	47	46	-	-	PUNCT
admet-2766	47	47	based	base	VERB
admet-2766	47	48	electrochemical	electrochemical	ADJ
admet-2766	47	49	biosensor	biosensor	NOUN
admet-2766	47	50	for	for	ADP
admet-2766	47	51	the	the	DET
admet-2766	47	52	detection	detection	NOUN
admet-2766	47	53	of	of	ADP
admet-2766	47	54	katg	katg	PROPN
admet-2766	47	55	gene	gene	NOUN
admet-2766	47	56	mutations	mutation	NOUN
admet-2766	47	57	experimental	experimental	ADJ
admet-2766	47	58	materials	material	NOUN
admet-2766	47	59	and	and	CCONJ
admet-2766	47	60	reagents	reagent	NOUN
admet-2766	47	61	the	the	DET
admet-2766	47	62	materials	material	NOUN
admet-2766	47	63	used	use	VERB
admet-2766	47	64	in	in	ADP
admet-2766	47	65	this	this	DET
admet-2766	47	66	research	research	NOUN
admet-2766	47	67	were	be	AUX
admet-2766	47	68	aqua	aqua	NOUN
admet-2766	47	69	pro	pro	ADJ
admet-2766	47	70	injection	injection	NOUN
admet-2766	47	71	(	(	PUNCT
admet-2766	47	72	pt	pt	PROPN
admet-2766	47	73	ikapharmindo	ikapharmindo	PROPN
admet-2766	47	74	putramas	putrama	NOUN
admet-2766	47	75	)	)	PUNCT
admet-2766	47	76	,	,	PUNCT
admet-2766	47	77	bovine	bovine	NOUN
admet-2766	47	78	serum	serum	NOUN
admet-2766	47	79	albumin	albumin	PROPN
admet-2766	47	80	(	(	PUNCT
admet-2766	47	81	bsa	bsa	PROPN
admet-2766	47	82	;	;	PUNCT
admet-2766	47	83	sigma	sigma	PROPN
admet-2766	47	84	aldrich	aldrich	PROPN
admet-2766	47	85	)	)	PUNCT
admet-2766	47	86	,	,	PUNCT
admet-2766	47	87	chloroauric	chloroauric	NOUN
admet-2766	47	88	acid	acid	NOUN
admet-2766	47	89	(	(	PUNCT
admet-2766	47	90	haucl4	haucl4	PROPN
admet-2766	47	91	.3h2o	.3h2o	PROPN
admet-2766	47	92	;	;	PUNCT
admet-2766	47	93	sigma	sigma	PROPN
admet-2766	47	94	aldrich	aldrich	PROPN
admet-2766	47	95	)	)	PUNCT
admet-2766	47	96	,	,	PUNCT
admet-2766	47	97	depc	depc	PROPN
admet-2766	47	98	treated	treat	VERB
admet-2766	47	99	water	water	NOUN
admet-2766	47	100	(	(	PUNCT
admet-2766	47	101	nippon	nippon	PROPN
admet-2766	47	102	gene	gene	NOUN
admet-2766	47	103	,	,	PUNCT
admet-2766	47	104	japan	japan	PROPN
admet-2766	47	105	)	)	PUNCT
admet-2766	47	106	,	,	PUNCT
admet-2766	47	107	dna	dna	PROPN
admet-2766	47	108	probe	probe	NOUN
admet-2766	47	109	-	-	PUNCT
admet-2766	47	110	ferrocene	ferrocene	NOUN
admet-2766	47	111	(	(	PUNCT
admet-2766	47	112	5’biotin	5’biotin	NUM
admet-2766	47	113	-	-	PUNCT
admet-2766	47	114	ttcctgcgctagtggtggccgtagctccagcat	ttcctgcgctagtggtggccgtagctccagcat	NOUN
admet-2766	47	115	-	-	PUNCT
admet-2766	47	116	fc3	fc3	NOUN
admet-2766	47	117	’	'	PUNCT
admet-2766	47	118	;	;	PUNCT
admet-2766	47	119	genescript	genescript	PROPN
admet-2766	47	120	,	,	PUNCT
admet-2766	47	121	singapore	singapore	PROPN
admet-2766	47	122	)	)	PUNCT
admet-2766	47	123	,	,	PUNCT
admet-2766	47	124	dna	dna	PROPN
admet-2766	47	125	target	target	NOUN
admet-2766	47	126	mutant	mutant	NOUN
admet-2766	47	127	(	(	PUNCT
admet-2766	47	128	5’cggaaccggtaaggacgcgatcaccaccggcatcgaggtcgtatggacg3	5’cggaaccggtaaggacgcgatcaccaccggcatcgaggtcgtatggacg3	NUM
admet-2766	47	129	’	'	PUNCT
admet-2766	47	130	;	;	PUNCT
admet-2766	47	131	facmac	facmac	PROPN
admet-2766	47	132	,	,	PUNCT
admet-2766	47	133	japan	japan	PROPN
admet-2766	47	134	)	)	PUNCT
admet-2766	47	135	,	,	PUNCT
admet-2766	47	136	dna	dna	PROPN
admet-2766	47	137	target	target	VERB
admet-2766	47	138	wild	wild	ADJ
admet-2766	47	139	type	type	NOUN
admet-2766	47	140	(	(	PUNCT
admet-2766	47	141	5’cggaaccggtaaggacgcgatcaccagcggcatcgaggtcgtatggacg3	5’cggaaccggtaaggacgcgatcaccagcggcatcgaggtcgtatggacg3	NUM
admet-2766	47	142	’	'	PUNCT
admet-2766	47	143	;	;	PUNCT
admet-2766	47	144	facmac	facmac	PROPN
admet-2766	47	145	,	,	PUNCT
admet-2766	47	146	japan	japan	PROPN
admet-2766	47	147	)	)	PUNCT
admet-2766	47	148	,	,	PUNCT
admet-2766	47	149	sgrna	sgrna	NOUN
admet-2766	47	150	(	(	PUNCT
admet-2766	47	151	5’cgcgaucaccaccggcaucg	5’cgcgaucaccaccggcaucg	NUM
admet-2766	47	152	;	;	PUNCT
admet-2766	47	153	genescript	genescript	ADJ
admet-2766	47	154	,	,	PUNCT
admet-2766	47	155	singapore	singapore	PROPN
admet-2766	47	156	)	)	PUNCT
admet-2766	47	157	,	,	PUNCT
admet-2766	47	158	ethanol	ethanol	NOUN
admet-2766	47	159	absolute	absolute	NOUN
admet-2766	47	160	(	(	PUNCT
admet-2766	47	161	c2h6o	c2h6o	NUM
admet-2766	47	162	;	;	PUNCT
admet-2766	47	163	merck	merck	PROPN
admet-2766	47	164	)	)	PUNCT
admet-2766	47	165	,	,	PUNCT
admet-2766	47	166	1-(3	1-(3	PROPN
admet-2766	47	167	-	-	PUNCT
admet-2766	47	168	dimethylaminopropyl)-3	dimethylaminopropyl)-3	PROPN
admet-2766	47	169	-	-	PUNCT
admet-2766	47	170	ethyl	ethyl	PROPN
admet-2766	47	171	carbodiimide	carbodiimide	NOUN
admet-2766	47	172	hydrochloride	hydrochloride	NOUN
admet-2766	47	173	(	(	PUNCT
admet-2766	47	174	edc	edc	PROPN
admet-2766	47	175	;	;	PUNCT
admet-2766	47	176	sigma	sigma	PROPN
admet-2766	47	177	aldrich	aldrich	PROPN
admet-2766	47	178	)	)	PUNCT
admet-2766	47	179	,	,	PUNCT
admet-2766	47	180	3	3	NUM
admet-2766	47	181	-	-	PUNCT
admet-2766	47	182	mercaptopropionic	mercaptopropionic	ADJ
admet-2766	47	183	acid	acid	NOUN
admet-2766	47	184	(	(	PUNCT
admet-2766	47	185	mpa	mpa	PROPN
admet-2766	47	186	;	;	PUNCT
admet-2766	47	187	sigma	sigma	PROPN
admet-2766	47	188	aldrich	aldrich	PROPN
admet-2766	47	189	)	)	PUNCT
admet-2766	47	190	,	,	PUNCT
admet-2766	47	191	n	n	CCONJ
admet-2766	47	192	-	-	PUNCT
admet-2766	47	193	hydroxysuccinimide	hydroxysuccinimide	NOUN
admet-2766	47	194	(	(	PUNCT
admet-2766	47	195	nhs	nhs	NOUN
admet-2766	47	196	;	;	PUNCT
admet-2766	47	197	sigma	sigma	PROPN
admet-2766	47	198	aldrich	aldrich	PROPN
admet-2766	47	199	)	)	PUNCT
admet-2766	47	200	,	,	PUNCT
admet-2766	47	201	potassium	potassium	NOUN
admet-2766	47	202	chloride	chloride	NOUN
admet-2766	47	203	(	(	PUNCT
admet-2766	47	204	kcl	kcl	NOUN
admet-2766	47	205	;	;	PUNCT
admet-2766	47	206	merck	merck	PROPN
admet-2766	47	207	)	)	PUNCT
admet-2766	47	208	,	,	PUNCT
admet-2766	47	209	potassium	potassium	NOUN
admet-2766	47	210	ferricyanide	ferricyanide	NOUN
admet-2766	47	211	(	(	PUNCT
admet-2766	47	212	[	[	X
admet-2766	47	213	k3[fe(cn)6	k3[fe(cn)6	PROPN
admet-2766	47	214	]	]	PUNCT
admet-2766	47	215	;	;	PUNCT
admet-2766	47	216	sigma	sigma	PROPN
admet-2766	47	217	aldrich	aldrich	PROPN
admet-2766	47	218	)	)	PUNCT
admet-2766	47	219	,	,	PUNCT
admet-2766	47	220	phosphate	phosphate	NOUN
admet-2766	47	221	buffer	buffer	NOUN
admet-2766	47	222	saline	saline	NOUN
admet-2766	47	223	10x	10x	NOUN
admet-2766	47	224	(	(	PUNCT
admet-2766	47	225	pbs	pbs	PROPN
admet-2766	47	226	;	;	PUNCT
admet-2766	47	227	himedia	himedia	PROPN
admet-2766	47	228	,	,	PUNCT
admet-2766	47	229	india	india	PROPN
admet-2766	47	230	)	)	PUNCT
admet-2766	47	231	,	,	PUNCT
admet-2766	47	232	streptavidin	streptavidin	PROPN
admet-2766	47	233	(	(	PUNCT
admet-2766	47	234	promega	promega	NOUN
admet-2766	47	235	)	)	PUNCT
admet-2766	47	236	,	,	PUNCT
admet-2766	47	237	sulfuric	sulfuric	NOUN
admet-2766	47	238	acid	acid	NOUN
admet-2766	47	239	(	(	PUNCT
admet-2766	47	240	h2so4	h2so4	PROPN
admet-2766	47	241	;	;	PUNCT
admet-2766	47	242	merck	merck	PROPN
admet-2766	47	243	)	)	PUNCT
admet-2766	47	244	,	,	PUNCT
admet-2766	47	245	and	and	CCONJ
admet-2766	47	246	screen	screen	NOUN
admet-2766	47	247	-	-	PUNCT
admet-2766	47	248	printed	print	VERB
admet-2766	47	249	carbon	carbon	NOUN
admet-2766	47	250	electrode	electrode	NOUN
admet-2766	47	251	consists	consist	VERB
admet-2766	47	252	of	of	ADP
admet-2766	47	253	carbon	carbon	NOUN
admet-2766	47	254	-	-	PUNCT
admet-2766	47	255	based	base	VERB
admet-2766	47	256	working	working	NOUN
admet-2766	47	257	(	(	PUNCT
admet-2766	47	258	diameter	diameter	NOUN
admet-2766	47	259	of	of	ADP
admet-2766	47	260	0.40	0.40	NUM
admet-2766	47	261	cm	cm	NOUN
admet-2766	47	262	)	)	PUNCT
admet-2766	47	263	,	,	PUNCT
admet-2766	47	264	carbon	carbon	NOUN
admet-2766	47	265	auxiliary	auxiliary	ADJ
admet-2766	47	266	electrodes	electrode	NOUN
admet-2766	47	267	,	,	PUNCT
admet-2766	47	268	and	and	CCONJ
admet-2766	47	269	silver	silver	NOUN
admet-2766	47	270	as	as	ADP
admet-2766	47	271	a	a	DET
admet-2766	47	272	reference	reference	NOUN
admet-2766	47	273	electrode	electrode	NOUN
admet-2766	47	274	(	(	PUNCT
admet-2766	47	275	metrohm	metrohm	PRON
admet-2766	47	276	dropsens	dropsen	NOUN
admet-2766	47	277	,	,	PUNCT
admet-2766	47	278	spain	spain	PROPN
admet-2766	47	279	)	)	PUNCT
admet-2766	47	280	.	.	PUNCT
admet-2766	48	1	instrumentation	instrumentation	NOUN
admet-2766	48	2	the	the	DET
admet-2766	48	3	instrument	instrument	NOUN
admet-2766	48	4	used	use	VERB
admet-2766	48	5	was	be	AUX
admet-2766	48	6	zp	zp	NOUN
admet-2766	48	7	potentiostat	potentiostat	NOUN
admet-2766	48	8	,	,	PUNCT
admet-2766	48	9	which	which	PRON
admet-2766	48	10	was	be	AUX
admet-2766	48	11	connected	connect	VERB
admet-2766	48	12	to	to	ADP
admet-2766	48	13	a	a	DET
admet-2766	48	14	computer	computer	NOUN
admet-2766	48	15	using	use	VERB
admet-2766	48	16	pstrace	pstrace	NOUN
admet-2766	48	17	5.11	5.11	NUM
admet-2766	48	18	software	software	NOUN
admet-2766	48	19	(	(	PUNCT
admet-2766	48	20	zimmer	zimmer	PROPN
admet-2766	48	21	&	&	CCONJ
admet-2766	48	22	peacock	peacock	PROPN
admet-2766	48	23	,	,	PUNCT
admet-2766	48	24	uk	uk	PROPN
admet-2766	48	25	)	)	PUNCT
admet-2766	48	26	,	,	PUNCT
admet-2766	48	27	a	a	DET
admet-2766	48	28	scanning	scanning	NOUN
admet-2766	48	29	electron	electron	NOUN
admet-2766	48	30	microscope	microscope	NOUN
admet-2766	48	31	(	(	PUNCT
admet-2766	48	32	sem	sem	PROPN
admet-2766	48	33	,	,	PUNCT
admet-2766	48	34	jeol	jeol	PROPN
admet-2766	48	35	jcm-6000	jcm-6000	PROPN
admet-2766	48	36	)	)	PUNCT
admet-2766	48	37	,	,	PUNCT
admet-2766	48	38	an	an	DET
admet-2766	48	39	incubator	incubator	NOUN
admet-2766	48	40	(	(	PUNCT
admet-2766	48	41	joanlab	joanlab	PROPN
admet-2766	48	42	)	)	PUNCT
admet-2766	48	43	,	,	PUNCT
admet-2766	48	44	a	a	DET
admet-2766	48	45	micropipette	micropipette	NOUN
admet-2766	48	46	(	(	PUNCT
admet-2766	48	47	dragonlab	dragonlab	PROPN
admet-2766	48	48	)	)	PUNCT
admet-2766	48	49	,	,	PUNCT
admet-2766	48	50	a	a	DET
admet-2766	48	51	microtube	microtube	NOUN
admet-2766	48	52	(	(	PUNCT
admet-2766	48	53	labselect	labselect	NOUN
admet-2766	48	54	)	)	PUNCT
admet-2766	48	55	,	,	PUNCT
admet-2766	48	56	and	and	CCONJ
admet-2766	48	57	a	a	DET
admet-2766	48	58	micropipette	micropipette	NOUN
admet-2766	48	59	tip	tip	NOUN
admet-2766	48	60	.	.	PUNCT
admet-2766	49	1	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	49	2	d.	d.	PROPN
admet-2766	49	3	a.	a.	PROPN
admet-2766	49	4	wulandari	wulandari	PROPN
admet-2766	49	5	et	et	PROPN
admet-2766	49	6	al	al	PROPN
admet-2766	49	7	.	.	PROPN
admet-2766	49	8	admet	admet	PROPN
admet-2766	49	9	&	&	CCONJ
admet-2766	49	10	dmpk	dmpk	PROPN
admet-2766	49	11	13(3	13(3	NUM
admet-2766	49	12	)	)	PUNCT
admet-2766	49	13	(	(	PUNCT
admet-2766	49	14	2025	2025	NUM
admet-2766	49	15	)	)	PUNCT
admet-2766	49	16	2766	2766	NUM
admet-2766	49	17	4	4	NUM
admet-2766	49	18	dna	dna	PROPN
admet-2766	49	19	sequence	sequence	NOUN
admet-2766	49	20	database	database	NOUN
admet-2766	49	21	of	of	ADP
admet-2766	49	22	mtb	mtb	NOUN
admet-2766	49	23	the	the	DET
admet-2766	49	24	grna	grna	NOUN
admet-2766	49	25	sequence	sequence	NOUN
admet-2766	49	26	was	be	AUX
admet-2766	49	27	determined	determine	VERB
admet-2766	49	28	from	from	ADP
admet-2766	49	29	the	the	DET
admet-2766	49	30	whole	whole	ADJ
admet-2766	49	31	genome	genome	NOUN
admet-2766	49	32	sequence	sequence	NOUN
admet-2766	49	33	of	of	ADP
admet-2766	49	34	mtb	mtb	NOUN
admet-2766	49	35	(	(	PUNCT
admet-2766	49	36	h37rv	h37rv	ADJ
admet-2766	49	37	)	)	PUNCT
admet-2766	49	38	that	that	PRON
admet-2766	49	39	is	be	AUX
admet-2766	49	40	available	available	ADJ
admet-2766	49	41	at	at	ADP
admet-2766	49	42	the	the	DET
admet-2766	49	43	genbank	genbank	PROPN
admet-2766	49	44	national	national	PROPN
admet-2766	49	45	center	center	PROPN
admet-2766	49	46	of	of	ADP
admet-2766	49	47	biotechnology	biotechnology	NOUN
admet-2766	49	48	information	information	NOUN
admet-2766	49	49	(	(	PUNCT
admet-2766	49	50	ncbi	ncbi	NOUN
admet-2766	49	51	)	)	PUNCT
admet-2766	50	1	[	[	X
admet-2766	50	2	29	29	NUM
admet-2766	50	3	]	]	PUNCT
admet-2766	50	4	,	,	PUNCT
admet-2766	50	5	with	with	ADP
admet-2766	50	6	the	the	DET
admet-2766	50	7	sequences	sequence	NOUN
admet-2766	50	8	of	of	ADP
admet-2766	50	9	the	the	DET
admet-2766	50	10	rpob	rpob	ADJ
admet-2766	50	11	gene	gene	NOUN
admet-2766	50	12	[	[	X
admet-2766	50	13	30	30	NUM
admet-2766	50	14	]	]	PUNCT
admet-2766	50	15	and	and	CCONJ
admet-2766	50	16	katg	katg	PROPN
admet-2766	50	17	gene	gene	NOUN
admet-2766	50	18	[	[	X
admet-2766	50	19	31	31	NUM
admet-2766	50	20	]	]	PUNCT
admet-2766	50	21	.	.	PUNCT
admet-2766	51	1	prediction	prediction	NOUN
admet-2766	51	2	of	of	ADP
admet-2766	51	3	crispr	crispr	ADJ
admet-2766	51	4	/	/	SYM
admet-2766	51	5	cas9	cas9	NOUN
admet-2766	51	6	grna	grna	NOUN
admet-2766	51	7	sequences	sequence	VERB
admet-2766	51	8	the	the	DET
admet-2766	51	9	selection	selection	NOUN
admet-2766	51	10	of	of	ADP
admet-2766	51	11	grna	grna	NOUN
admet-2766	51	12	for	for	ADP
admet-2766	51	13	detecting	detect	VERB
admet-2766	51	14	mutations	mutation	NOUN
admet-2766	51	15	in	in	ADP
admet-2766	51	16	inh	inh	PROPN
admet-2766	51	17	-	-	PUNCT
admet-2766	51	18	r	r	NOUN
admet-2766	51	19	involves	involve	VERB
admet-2766	51	20	identifying	identify	VERB
admet-2766	51	21	the	the	DET
admet-2766	51	22	mutation	mutation	NOUN
admet-2766	51	23	points	point	NOUN
admet-2766	51	24	at	at	ADP
admet-2766	51	25	specific	specific	ADJ
admet-2766	51	26	amino	amino	NOUN
admet-2766	51	27	acid	acid	NOUN
admet-2766	51	28	positions	position	NOUN
admet-2766	51	29	,	,	PUNCT
admet-2766	51	30	as	as	SCONJ
admet-2766	51	31	determined	determine	VERB
admet-2766	51	32	from	from	ADP
admet-2766	51	33	studies	study	NOUN
admet-2766	51	34	analysing	analyse	VERB
admet-2766	51	35	the	the	DET
admet-2766	51	36	distribution	distribution	NOUN
admet-2766	51	37	of	of	ADP
admet-2766	51	38	mutations	mutation	NOUN
admet-2766	51	39	across	across	ADP
admet-2766	51	40	various	various	ADJ
admet-2766	51	41	regions	region	NOUN
admet-2766	51	42	.	.	PUNCT
admet-2766	52	1	based	base	VERB
admet-2766	52	2	on	on	ADP
admet-2766	52	3	mutation	mutation	NOUN
admet-2766	52	4	distribution	distribution	NOUN
admet-2766	52	5	data	datum	NOUN
admet-2766	52	6	for	for	ADP
admet-2766	52	7	the	the	DET
admet-2766	52	8	katg	katg	NOUN
admet-2766	52	9	genes	gene	NOUN
admet-2766	52	10	isolates	isolate	NOUN
admet-2766	52	11	from	from	ADP
admet-2766	52	12	various	various	ADJ
admet-2766	52	13	geographic	geographic	ADJ
admet-2766	52	14	regions	region	NOUN
admet-2766	52	15	(	(	PUNCT
admet-2766	52	16	supplementary	supplementary	ADJ
admet-2766	52	17	table	table	NOUN
admet-2766	52	18	s1	s1	NOUN
admet-2766	52	19	and	and	CCONJ
admet-2766	52	20	supplementary	supplementary	ADJ
admet-2766	52	21	table	table	NOUN
admet-2766	52	22	s2	s2	PROPN
admet-2766	52	23	)	)	PUNCT
admet-2766	52	24	,	,	PUNCT
admet-2766	52	25	it	it	PRON
admet-2766	52	26	can	can	AUX
admet-2766	52	27	be	be	AUX
admet-2766	52	28	concluded	conclude	VERB
admet-2766	52	29	that	that	SCONJ
admet-2766	52	30	the	the	DET
admet-2766	52	31	most	most	ADV
admet-2766	52	32	frequent	frequent	ADJ
admet-2766	52	33	mutations	mutation	NOUN
admet-2766	52	34	in	in	ADP
admet-2766	52	35	the	the	DET
admet-2766	52	36	katg	katg	PROPN
admet-2766	52	37	gene	gene	NOUN
admet-2766	52	38	are	be	AUX
admet-2766	52	39	predominantly	predominantly	ADV
admet-2766	52	40	located	locate	VERB
admet-2766	52	41	at	at	ADP
admet-2766	52	42	amino	amino	NOUN
admet-2766	52	43	acid	acid	NOUN
admet-2766	52	44	position	position	NOUN
admet-2766	52	45	315	315	NUM
admet-2766	52	46	.	.	PUNCT
admet-2766	53	1	therefore	therefore	ADV
admet-2766	53	2	,	,	PUNCT
admet-2766	53	3	the	the	DET
admet-2766	53	4	selection	selection	NOUN
admet-2766	53	5	of	of	ADP
admet-2766	53	6	grna	grna	NOUN
admet-2766	53	7	candidates	candidate	NOUN
admet-2766	53	8	can	can	AUX
admet-2766	53	9	be	be	AUX
admet-2766	53	10	guided	guide	VERB
admet-2766	53	11	by	by	ADP
admet-2766	53	12	the	the	DET
admet-2766	53	13	mutation	mutation	NOUN
admet-2766	53	14	patterns	pattern	NOUN
admet-2766	53	15	in	in	ADP
admet-2766	53	16	the	the	DET
admet-2766	53	17	katg	katg	NOUN
admet-2766	53	18	genes	gene	NOUN
admet-2766	53	19	across	across	ADP
admet-2766	53	20	these	these	DET
admet-2766	53	21	regions	region	NOUN
admet-2766	53	22	.	.	PUNCT
admet-2766	54	1	candidate	candidate	NOUN
admet-2766	54	2	grnas	grna	NOUN
admet-2766	54	3	were	be	AUX
admet-2766	54	4	identified	identify	VERB
admet-2766	54	5	using	use	VERB
admet-2766	54	6	the	the	DET
admet-2766	54	7	benchling	benchle	VERB
admet-2766	54	8	platform	platform	NOUN
admet-2766	54	9	by	by	ADP
admet-2766	54	10	examining	examine	VERB
admet-2766	54	11	the	the	DET
admet-2766	54	12	highest	high	ADJ
admet-2766	54	13	on	on	ADP
admet-2766	54	14	-	-	PUNCT
admet-2766	54	15	target	target	NOUN
admet-2766	54	16	and	and	CCONJ
admet-2766	54	17	off	off	ADP
admet-2766	54	18	-	-	PUNCT
admet-2766	54	19	target	target	NOUN
admet-2766	54	20	scores	score	NOUN
admet-2766	54	21	.	.	PUNCT
admet-2766	55	1	additionally	additionally	ADV
admet-2766	55	2	,	,	PUNCT
admet-2766	55	3	the	the	DET
admet-2766	55	4	determination	determination	NOUN
admet-2766	55	5	of	of	ADP
admet-2766	55	6	grna	grna	NOUN
admet-2766	55	7	candidates	candidate	NOUN
admet-2766	55	8	for	for	ADP
admet-2766	55	9	mutated	mutate	VERB
admet-2766	55	10	dna	dna	NOUN
admet-2766	55	11	by	by	ADP
admet-2766	55	12	modifying	modify	VERB
admet-2766	55	13	the	the	DET
admet-2766	55	14	side	side	NOUN
admet-2766	55	15	of	of	ADP
admet-2766	55	16	the	the	DET
admet-2766	55	17	mutations	mutation	NOUN
admet-2766	55	18	in	in	ADP
admet-2766	55	19	wild	wild	ADJ
admet-2766	55	20	-	-	PUNCT
admet-2766	55	21	type	type	NOUN
admet-2766	55	22	grna	grna	NOUN
admet-2766	55	23	.	.	PUNCT
admet-2766	56	1	modification	modification	NOUN
admet-2766	56	2	of	of	ADP
admet-2766	56	3	spce	spce	NOUN
admet-2766	56	4	with	with	ADP
admet-2766	56	5	gold	gold	ADJ
admet-2766	56	6	nanoparticles	nanoparticle	NOUN
admet-2766	56	7	spce	spce	NOUN
admet-2766	56	8	was	be	AUX
admet-2766	56	9	modified	modify	VERB
admet-2766	56	10	with	with	ADP
admet-2766	56	11	aunps	aunps	NOUN
admet-2766	56	12	using	use	VERB
admet-2766	56	13	the	the	DET
admet-2766	56	14	electrodeposition	electrodeposition	NOUN
admet-2766	56	15	method	method	NOUN
admet-2766	56	16	.	.	PUNCT
admet-2766	57	1	the	the	DET
admet-2766	57	2	electrode	electrode	NOUN
admet-2766	57	3	was	be	AUX
admet-2766	57	4	first	first	ADV
admet-2766	57	5	treated	treat	VERB
admet-2766	57	6	with	with	ADP
admet-2766	57	7	deionized	deionize	VERB
admet-2766	57	8	water	water	NOUN
admet-2766	57	9	and	and	CCONJ
admet-2766	57	10	dried	dry	VERB
admet-2766	57	11	at	at	ADP
admet-2766	57	12	room	room	NOUN
admet-2766	57	13	temperature	temperature	NOUN
admet-2766	57	14	.	.	PUNCT
admet-2766	58	1	pre	pre	ADJ
admet-2766	58	2	-	-	NOUN
admet-2766	58	3	treatment	treatment	NOUN
admet-2766	58	4	was	be	AUX
admet-2766	58	5	carried	carry	VERB
admet-2766	58	6	out	out	ADP
admet-2766	58	7	in	in	ADP
admet-2766	58	8	0.1	0.1	NUM
admet-2766	58	9	m	m	NOUN
admet-2766	58	10	h2so4	h2so4	NOUN
admet-2766	58	11	using	use	VERB
admet-2766	58	12	cyclic	cyclic	ADJ
admet-2766	58	13	voltammetry	voltammetry	NOUN
admet-2766	58	14	for	for	ADP
admet-2766	58	15	10	10	NUM
admet-2766	58	16	cycles	cycle	NOUN
admet-2766	58	17	.	.	PUNCT
admet-2766	59	1	then	then	ADV
admet-2766	59	2	,	,	PUNCT
admet-2766	59	3	50	50	NUM
admet-2766	59	4	μl	μl	ADP
admet-2766	59	5	of	of	ADP
admet-2766	59	6	1.0	1.0	NUM
admet-2766	59	7	mm	mm	NOUN
admet-2766	59	8	haucl4	haucl4	NOUN
admet-2766	59	9	in	in	ADP
admet-2766	59	10	0.1	0.1	NUM
admet-2766	59	11	m	m	NOUN
admet-2766	59	12	kcl	kcl	PROPN
admet-2766	59	13	was	be	AUX
admet-2766	59	14	dropped	drop	VERB
admet-2766	59	15	onto	onto	ADP
admet-2766	59	16	the	the	DET
admet-2766	59	17	electrode	electrode	NOUN
admet-2766	59	18	surface	surface	NOUN
admet-2766	59	19	and	and	CCONJ
admet-2766	59	20	electrodeposited	electrodeposite	VERB
admet-2766	59	21	using	use	VERB
admet-2766	59	22	chronoamperometry	chronoamperometry	NOUN
admet-2766	59	23	.	.	PUNCT
admet-2766	60	1	after	after	ADP
admet-2766	60	2	modification	modification	NOUN
admet-2766	60	3	,	,	PUNCT
admet-2766	60	4	the	the	DET
admet-2766	60	5	spce	spce	NOUN
admet-2766	60	6	was	be	AUX
admet-2766	60	7	rinsed	rinse	VERB
admet-2766	60	8	with	with	ADP
admet-2766	60	9	distilled	distil	VERB
admet-2766	60	10	water	water	NOUN
admet-2766	60	11	and	and	CCONJ
admet-2766	60	12	dried	dry	VERB
admet-2766	60	13	.	.	PUNCT
admet-2766	61	1	the	the	DET
admet-2766	61	2	modified	modified	ADJ
admet-2766	61	3	electrode	electrode	NOUN
admet-2766	61	4	was	be	AUX
admet-2766	61	5	characterized	characterize	VERB
admet-2766	61	6	using	use	VERB
admet-2766	61	7	differential	differential	ADJ
admet-2766	61	8	pulse	pulse	NOUN
admet-2766	61	9	voltammetry	voltammetry	NOUN
admet-2766	61	10	(	(	PUNCT
admet-2766	61	11	dpv	dpv	PROPN
admet-2766	61	12	)	)	PUNCT
admet-2766	61	13	in	in	ADP
admet-2766	61	14	10	10	NUM
admet-2766	61	15	mm	mm	PROPN
admet-2766	61	16	k3[fe(cn)6	k3[fe(cn)6	PROPN
admet-2766	61	17	]	]	PUNCT
admet-2766	61	18	with	with	ADP
admet-2766	61	19	0.1	0.1	NUM
admet-2766	61	20	m	m	NOUN
admet-2766	61	21	kcl	kcl	NOUN
admet-2766	61	22	(	(	PUNCT
admet-2766	61	23	conditions	condition	NOUN
admet-2766	61	24	:	:	PUNCT
admet-2766	61	25	pretreatment	pretreatment	NOUN
admet-2766	61	26	settings	setting	NOUN
admet-2766	61	27	:	:	PUNCT
admet-2766	61	28	e	e	X
admet-2766	61	29	condition	condition	NOUN
admet-2766	61	30	:	:	PUNCT
admet-2766	61	31	-0.2	-0.2	NUM
admet-2766	61	32	v	v	NOUN
admet-2766	61	33	;	;	PUNCT
admet-2766	61	34	t	t	X
admet-2766	61	35	condition	condition	NOUN
admet-2766	61	36	:	:	PUNCT
admet-2766	61	37	10	10	NUM
admet-2766	61	38	s	s	X
admet-2766	61	39	;	;	PUNCT
admet-2766	61	40	dpv	dpv	PROPN
admet-2766	61	41	settings	setting	NOUN
admet-2766	61	42	:	:	PUNCT
admet-2766	61	43	tequilibration	tequilibration	NOUN
admet-2766	61	44	:	:	PUNCT
admet-2766	61	45	0	0	NUM
admet-2766	61	46	s	s	X
admet-2766	61	47	,	,	PUNCT
admet-2766	61	48	ebegin	ebegin	NOUN
admet-2766	61	49	:	:	PUNCT
admet-2766	61	50	-0.2	-0.2	NUM
admet-2766	61	51	v	v	NOUN
admet-2766	61	52	,	,	PUNCT
admet-2766	61	53	eend	eend	VERB
admet-2766	61	54	:	:	PUNCT
admet-2766	61	55	0.5	0.5	NUM
admet-2766	61	56	v	v	NOUN
admet-2766	61	57	;	;	PUNCT
admet-2766	61	58	estep	estep	NOUN
admet-2766	61	59	:	:	PUNCT
admet-2766	61	60	0.004	0.004	NUM
admet-2766	61	61	v	v	NOUN
admet-2766	61	62	;	;	PUNCT
admet-2766	61	63	epulse	epulse	NOUN
admet-2766	61	64	:	:	PUNCT
admet-2766	61	65	0.025	0.025	NUM
admet-2766	61	66	v	v	NOUN
admet-2766	61	67	;	;	PUNCT
admet-2766	61	68	tpulse	tpulse	ADV
admet-2766	61	69	:	:	PUNCT
admet-2766	61	70	0.05	0.05	NUM
admet-2766	61	71	s	s	NOUN
admet-2766	61	72	,	,	PUNCT
admet-2766	61	73	scan	scan	ADJ
admet-2766	61	74	rate	rate	NOUN
admet-2766	61	75	0.008	0.008	NUM
admet-2766	61	76	v	v	NOUN
admet-2766	61	77	s1	s1	NOUN
admet-2766	61	78	)	)	PUNCT
admet-2766	61	79	to	to	PART
admet-2766	61	80	observe	observe	VERB
admet-2766	61	81	the	the	DET
admet-2766	61	82	redox	redox	ADJ
admet-2766	61	83	response	response	NOUN
admet-2766	61	84	of	of	ADP
admet-2766	61	85	the	the	DET
admet-2766	61	86	modified	modify	VERB
admet-2766	61	87	surface	surface	NOUN
admet-2766	61	88	.	.	PUNCT
admet-2766	62	1	immobilization	immobilization	NOUN
admet-2766	62	2	of	of	ADP
admet-2766	62	3	ferrocene	ferrocene	NOUN
admet-2766	62	4	-	-	PUNCT
admet-2766	62	5	labelled	label	VERB
admet-2766	62	6	dna	dna	NOUN
admet-2766	62	7	probe	probe	NOUN
admet-2766	62	8	(	(	PUNCT
admet-2766	62	9	dna	dna	PROPN
admet-2766	62	10	probe	probe	NOUN
admet-2766	62	11	-	-	PUNCT
admet-2766	62	12	fc	fc	PROPN
admet-2766	62	13	)	)	PUNCT
admet-2766	62	14	the	the	DET
admet-2766	62	15	spce	spce	PROPN
admet-2766	62	16	/	/	SYM
admet-2766	62	17	aunps	aunps	PROPN
admet-2766	62	18	electrode	electrode	NOUN
admet-2766	62	19	was	be	AUX
admet-2766	62	20	functionalized	functionalize	VERB
admet-2766	62	21	with	with	ADP
admet-2766	62	22	0.01	0.01	NUM
admet-2766	62	23	m	m	NOUN
admet-2766	62	24	mpa	mpa	NOUN
admet-2766	62	25	and	and	CCONJ
admet-2766	62	26	incubated	incubate	VERB
admet-2766	62	27	at	at	ADP
admet-2766	62	28	25	25	NUM
admet-2766	62	29	°	°	NOUN
admet-2766	62	30	c	c	NOUN
admet-2766	62	31	for	for	ADP
admet-2766	62	32	20	20	NUM
admet-2766	62	33	minutes	minute	NOUN
admet-2766	62	34	,	,	PUNCT
admet-2766	62	35	followed	follow	VERB
admet-2766	62	36	by	by	ADP
admet-2766	62	37	washing	wash	VERB
admet-2766	62	38	with	with	ADP
admet-2766	62	39	an	an	DET
admet-2766	62	40	ethanol	ethanol	NOUN
admet-2766	62	41	-	-	PUNCT
admet-2766	62	42	water	water	NOUN
admet-2766	62	43	mixture	mixture	NOUN
admet-2766	62	44	(	(	PUNCT
admet-2766	62	45	1:3	1:3	NUM
admet-2766	62	46	)	)	PUNCT
admet-2766	62	47	.	.	PUNCT
admet-2766	63	1	activation	activation	NOUN
admet-2766	63	2	was	be	AUX
admet-2766	63	3	performed	perform	VERB
admet-2766	63	4	by	by	ADP
admet-2766	63	5	adding	add	VERB
admet-2766	63	6	0.1	0.1	NUM
admet-2766	63	7	m	m	NOUN
admet-2766	63	8	edc	edc	PROPN
admet-2766	63	9	/	/	SYM
admet-2766	63	10	nhs	nhs	PROPN
admet-2766	63	11	(	(	PUNCT
admet-2766	63	12	1:1	1:1	NUM
admet-2766	63	13	)	)	PUNCT
admet-2766	63	14	,	,	PUNCT
admet-2766	63	15	incubating	incubate	VERB
admet-2766	63	16	at	at	ADP
admet-2766	63	17	25	25	NUM
admet-2766	63	18	°	°	NOUN
admet-2766	63	19	c	c	NOUN
admet-2766	63	20	for	for	ADP
admet-2766	63	21	60	60	NUM
admet-2766	63	22	minutes	minute	NOUN
admet-2766	63	23	,	,	PUNCT
admet-2766	63	24	and	and	CCONJ
admet-2766	63	25	rinsing	rinse	VERB
admet-2766	63	26	with	with	ADP
admet-2766	63	27	distilled	distil	VERB
admet-2766	63	28	water	water	NOUN
admet-2766	63	29	.	.	PUNCT
admet-2766	64	1	then	then	ADV
admet-2766	64	2	,	,	PUNCT
admet-2766	64	3	3	3	NUM
admet-2766	64	4	μl	μl	NOUN
admet-2766	64	5	of	of	ADP
admet-2766	64	6	streptavidin	streptavidin	PROPN
admet-2766	64	7	(	(	PUNCT
admet-2766	64	8	50	50	NUM
admet-2766	64	9	ppm	ppm	NOUN
admet-2766	64	10	)	)	PUNCT
admet-2766	64	11	was	be	AUX
admet-2766	64	12	added	add	VERB
admet-2766	64	13	to	to	ADP
admet-2766	64	14	the	the	DET
admet-2766	64	15	surface	surface	NOUN
admet-2766	64	16	and	and	CCONJ
admet-2766	64	17	incubated	incubate	VERB
admet-2766	64	18	at	at	ADP
admet-2766	64	19	4	4	NUM
admet-2766	64	20	°	°	ADP
admet-2766	64	21	c	c	NOUN
admet-2766	64	22	for	for	ADP
admet-2766	64	23	90	90	NUM
admet-2766	64	24	minutes	minute	NOUN
admet-2766	64	25	,	,	PUNCT
admet-2766	64	26	followed	follow	VERB
admet-2766	64	27	by	by	ADP
admet-2766	64	28	washing	wash	VERB
admet-2766	64	29	with	with	ADP
admet-2766	64	30	1×	1×	NUM
admet-2766	64	31	pbs	pbs	PROPN
admet-2766	64	32	.	.	PUNCT
admet-2766	65	1	subsequently	subsequently	ADV
admet-2766	65	2	,	,	PUNCT
admet-2766	65	3	3	3	NUM
admet-2766	65	4	μl	μl	NOUN
admet-2766	65	5	of	of	ADP
admet-2766	65	6	dna	dna	PROPN
admet-2766	65	7	probe	probe	PROPN
admet-2766	65	8	-	-	PUNCT
admet-2766	65	9	fc	fc	PROPN
admet-2766	65	10	(	(	PUNCT
admet-2766	65	11	2	2	NUM
admet-2766	65	12	μm	μm	NUM
admet-2766	65	13	)	)	PUNCT
admet-2766	65	14	was	be	AUX
admet-2766	65	15	immobilized	immobilize	VERB
admet-2766	65	16	onto	onto	ADP
admet-2766	65	17	the	the	DET
admet-2766	65	18	surface	surface	NOUN
admet-2766	65	19	and	and	CCONJ
admet-2766	65	20	incubated	incubate	VERB
admet-2766	65	21	at	at	ADP
admet-2766	65	22	25	25	NUM
admet-2766	65	23	°	°	NOUN
admet-2766	65	24	c	c	NOUN
admet-2766	65	25	for	for	ADP
admet-2766	65	26	60	60	NUM
admet-2766	65	27	minutes	minute	NOUN
admet-2766	65	28	.	.	PUNCT
admet-2766	66	1	after	after	ADP
admet-2766	66	2	washing	wash	VERB
admet-2766	66	3	with	with	ADP
admet-2766	66	4	1×	1×	NUM
admet-2766	66	5	pbs	pbs	PROPN
admet-2766	66	6	,	,	PUNCT
admet-2766	66	7	3	3	NUM
admet-2766	66	8	μl	μl	ADP
admet-2766	66	9	of	of	ADP
admet-2766	66	10	0.01	0.01	NUM
admet-2766	66	11	%	%	NOUN
admet-2766	66	12	bsa	bsa	PROPN
admet-2766	66	13	was	be	AUX
admet-2766	66	14	added	add	VERB
admet-2766	66	15	and	and	CCONJ
admet-2766	66	16	incubated	incubate	VERB
admet-2766	66	17	at	at	ADP
admet-2766	66	18	25	25	NUM
admet-2766	66	19	°	°	NOUN
admet-2766	66	20	c	c	NOUN
admet-2766	66	21	for	for	ADP
admet-2766	66	22	10	10	NUM
admet-2766	66	23	minutes	minute	NOUN
admet-2766	66	24	to	to	PART
admet-2766	66	25	block	block	VERB
admet-2766	66	26	non	non	ADJ
admet-2766	66	27	-	-	ADJ
admet-2766	66	28	specific	specific	ADJ
admet-2766	66	29	sites	site	NOUN
admet-2766	66	30	.	.	PUNCT
admet-2766	67	1	the	the	DET
admet-2766	67	2	final	final	ADJ
admet-2766	67	3	electrode	electrode	NOUN
admet-2766	67	4	was	be	AUX
admet-2766	67	5	rinsed	rinse	VERB
admet-2766	67	6	again	again	ADV
admet-2766	67	7	with	with	ADP
admet-2766	67	8	1×	1×	NUM
admet-2766	67	9	pbs	pbs	PROPN
admet-2766	67	10	.	.	PUNCT
admet-2766	68	1	electrochemical	electrochemical	ADJ
admet-2766	68	2	characterization	characterization	NOUN
admet-2766	68	3	was	be	AUX
admet-2766	68	4	performed	perform	VERB
admet-2766	68	5	using	use	VERB
admet-2766	68	6	square	square	ADJ
admet-2766	68	7	wave	wave	NOUN
admet-2766	68	8	voltammetry	voltammetry	NOUN
admet-2766	68	9	(	(	PUNCT
admet-2766	68	10	swv	swv	PROPN
admet-2766	68	11	)	)	PUNCT
admet-2766	68	12	in	in	ADP
admet-2766	68	13	1×	1×	NUM
admet-2766	68	14	pbs	pbs	PROPN
admet-2766	68	15	(	(	PUNCT
admet-2766	68	16	conditions	condition	NOUN
admet-2766	68	17	:	:	PUNCT
admet-2766	68	18	equilibration	equilibration	NOUN
admet-2766	68	19	time	time	NOUN
admet-2766	68	20	0	0	NUM
admet-2766	68	21	s	s	NOUN
admet-2766	68	22	,	,	PUNCT
admet-2766	68	23	potential	potential	ADJ
admet-2766	68	24	range	range	NOUN
admet-2766	68	25	-0.1	-0.1	PROPN
admet-2766	68	26	to	to	ADP
admet-2766	68	27	0.5	0.5	NUM
admet-2766	68	28	v	v	NOUN
admet-2766	68	29	,	,	PUNCT
admet-2766	68	30	step	step	VERB
admet-2766	68	31	potential	potential	ADJ
admet-2766	68	32	0.004	0.004	NUM
admet-2766	68	33	v	v	NOUN
admet-2766	68	34	,	,	PUNCT
admet-2766	68	35	amplitude	amplitude	NOUN
admet-2766	68	36	0.025	0.025	NUM
admet-2766	68	37	v	v	NOUN
admet-2766	68	38	,	,	PUNCT
admet-2766	68	39	and	and	CCONJ
admet-2766	68	40	frequency	frequency	NOUN
admet-2766	68	41	25	25	NUM
admet-2766	68	42	hz	hz	NOUN
admet-2766	68	43	)	)	PUNCT
admet-2766	68	44	to	to	PART
admet-2766	68	45	measure	measure	VERB
admet-2766	68	46	the	the	DET
admet-2766	68	47	redox	redox	ADJ
admet-2766	68	48	signal	signal	NOUN
admet-2766	68	49	of	of	ADP
admet-2766	68	50	the	the	DET
admet-2766	68	51	ferrocene	ferrocene	NOUN
admet-2766	68	52	label	label	NOUN
admet-2766	68	53	.	.	PUNCT
admet-2766	69	1	target	target	NOUN
admet-2766	69	2	recognition	recognition	NOUN
admet-2766	69	3	and	and	CCONJ
admet-2766	69	4	cleavage	cleavage	NOUN
admet-2766	69	5	by	by	ADP
admet-2766	69	6	the	the	DET
admet-2766	69	7	cas9	cas9	NOUN
admet-2766	69	8	-	-	PUNCT
admet-2766	69	9	grna	grna	NOUN
admet-2766	69	10	complex	complex	NOUN
admet-2766	69	11	a	a	DET
admet-2766	69	12	mixture	mixture	NOUN
admet-2766	69	13	of	of	ADP
admet-2766	69	14	grna	grna	NOUN
admet-2766	69	15	(	(	PUNCT
admet-2766	69	16	100	100	NUM
admet-2766	69	17	nm	nm	NOUN
admet-2766	69	18	)	)	PUNCT
admet-2766	69	19	,	,	PUNCT
admet-2766	69	20	cas9	cas9	NOUN
admet-2766	69	21	(	(	PUNCT
admet-2766	69	22	100	100	NUM
admet-2766	69	23	nm	nm	NOUN
admet-2766	69	24	)	)	PUNCT
admet-2766	69	25	,	,	PUNCT
admet-2766	69	26	rnase	rnase	PROPN
admet-2766	69	27	inhibitor	inhibitor	NOUN
admet-2766	69	28	,	,	PUNCT
admet-2766	69	29	10×	10×	NUM
admet-2766	69	30	cas9	cas9	NOUN
admet-2766	69	31	reaction	reaction	NOUN
admet-2766	69	32	buffer	buffer	NOUN
admet-2766	69	33	,	,	PUNCT
admet-2766	69	34	and	and	CCONJ
admet-2766	69	35	1×	1×	NUM
admet-2766	69	36	pbs	pbs	PROPN
admet-2766	69	37	was	be	AUX
admet-2766	69	38	prepared	prepare	VERB
admet-2766	69	39	in	in	ADP
admet-2766	69	40	a	a	DET
admet-2766	69	41	microtube	microtube	NOUN
admet-2766	69	42	and	and	CCONJ
admet-2766	69	43	incubated	incubate	VERB
admet-2766	69	44	at	at	ADP
admet-2766	69	45	37	37	NUM
admet-2766	69	46	°	°	ADP
admet-2766	69	47	c	c	NOUN
admet-2766	69	48	for	for	ADP
admet-2766	69	49	10	10	NUM
admet-2766	69	50	minutes	minute	NOUN
admet-2766	69	51	to	to	PART
admet-2766	69	52	form	form	VERB
admet-2766	69	53	the	the	DET
admet-2766	69	54	cas9	cas9	NOUN
admet-2766	69	55	-	-	PUNCT
admet-2766	69	56	sgrna	sgrna	NOUN
admet-2766	69	57	complex	complex	NOUN
admet-2766	69	58	.	.	PUNCT
admet-2766	70	1	separately	separately	ADV
admet-2766	70	2	,	,	PUNCT
admet-2766	70	3	the	the	DET
admet-2766	70	4	target	target	NOUN
admet-2766	70	5	single	single	ADV
admet-2766	70	6	-	-	PUNCT
admet-2766	70	7	stranded	strand	VERB
admet-2766	70	8	dna	dna	NOUN
admet-2766	70	9	(	(	PUNCT
admet-2766	70	10	ssdna	ssdna	ADV
admet-2766	70	11	)	)	PUNCT
admet-2766	70	12	was	be	AUX
admet-2766	70	13	applied	apply	VERB
admet-2766	70	14	onto	onto	ADP
admet-2766	70	15	the	the	DET
admet-2766	70	16	spce	spce	PROPN
admet-2766	70	17	/	/	SYM
admet-2766	70	18	aunps	aunps	PROPN
admet-2766	70	19	/	/	SYM
admet-2766	70	20	mpa	mpa	PROPN
admet-2766	70	21	-	-	PUNCT
admet-2766	70	22	edc	edc	PROPN
admet-2766	70	23	-	-	PUNCT
admet-2766	70	24	nhs	nhs	PROPN
admet-2766	70	25	/	/	SYM
admet-2766	70	26	stv	stv	PROPN
admet-2766	70	27	/	/	SYM
admet-2766	70	28	dna	dna	PROPN
admet-2766	70	29	probe	probe	NOUN
admet-2766	70	30	-	-	PUNCT
admet-2766	70	31	fcmodified	fcmodifie	VERB
admet-2766	70	32	electrode	electrode	NOUN
admet-2766	70	33	and	and	CCONJ
admet-2766	70	34	incubated	incubate	VERB
admet-2766	70	35	at	at	ADP
admet-2766	70	36	37	37	NUM
admet-2766	70	37	°	°	ADP
admet-2766	70	38	c	c	NOUN
admet-2766	70	39	for	for	ADP
admet-2766	70	40	10	10	NUM
admet-2766	70	41	minutes	minute	NOUN
admet-2766	70	42	,	,	PUNCT
admet-2766	70	43	followed	follow	VERB
admet-2766	70	44	by	by	ADP
admet-2766	70	45	washing	wash	VERB
admet-2766	70	46	with	with	ADP
admet-2766	70	47	1×	1×	NUM
admet-2766	70	48	pbs	pbs	PROPN
admet-2766	70	49	.	.	PUNCT
admet-2766	71	1	the	the	DET
admet-2766	71	2	cas9	cas9	NOUN
admet-2766	71	3	-	-	PUNCT
admet-2766	71	4	sgrna	sgrna	NOUN
admet-2766	71	5	complex	complex	NOUN
admet-2766	71	6	was	be	AUX
admet-2766	71	7	added	add	VERB
admet-2766	71	8	to	to	ADP
admet-2766	71	9	the	the	DET
admet-2766	71	10	electrode	electrode	NOUN
admet-2766	71	11	surface	surface	NOUN
admet-2766	71	12	and	and	CCONJ
admet-2766	71	13	incubated	incubate	VERB
admet-2766	71	14	at	at	ADP
admet-2766	71	15	37	37	NUM
admet-2766	71	16	°	°	NOUN
admet-2766	71	17	c	c	NOUN
admet-2766	71	18	for	for	ADP
admet-2766	71	19	120	120	NUM
admet-2766	71	20	minutes	minute	NOUN
admet-2766	71	21	.	.	PUNCT
admet-2766	72	1	after	after	ADP
admet-2766	72	2	incubation	incubation	NOUN
admet-2766	72	3	,	,	PUNCT
admet-2766	72	4	the	the	DET
admet-2766	72	5	electrode	electrode	NOUN
admet-2766	72	6	was	be	AUX
admet-2766	72	7	rinsed	rinse	VERB
admet-2766	72	8	with	with	ADP
admet-2766	72	9	1×	1×	NUM
admet-2766	72	10	pbs	pbs	PROPN
admet-2766	72	11	.	.	PUNCT
admet-2766	73	1	electrochemical	electrochemical	ADJ
admet-2766	73	2	characterization	characterization	NOUN
admet-2766	73	3	was	be	AUX
admet-2766	73	4	performed	perform	VERB
admet-2766	73	5	using	use	VERB
admet-2766	73	6	swv	swv	NOUN
admet-2766	73	7	in	in	ADP
admet-2766	73	8	1×	1×	NUM
admet-2766	73	9	pbs	pbs	PROPN
admet-2766	73	10	(	(	PUNCT
admet-2766	73	11	conditions	condition	NOUN
admet-2766	73	12	:	:	PUNCT
admet-2766	73	13	equilibration	equilibration	NOUN
admet-2766	73	14	time	time	NOUN
admet-2766	73	15	0	0	NUM
admet-2766	73	16	s	s	NOUN
admet-2766	73	17	,	,	PUNCT
admet-2766	73	18	potential	potential	ADJ
admet-2766	73	19	range	range	NOUN
admet-2766	73	20	-0.1	-0.1	PROPN
admet-2766	73	21	to	to	ADP
admet-2766	73	22	0.5	0.5	NUM
admet-2766	73	23	v	v	NOUN
admet-2766	73	24	,	,	PUNCT
admet-2766	73	25	step	step	VERB
admet-2766	73	26	potential	potential	ADJ
admet-2766	73	27	0.004	0.004	NUM
admet-2766	73	28	v	v	NOUN
admet-2766	73	29	,	,	PUNCT
admet-2766	73	30	amplitude	amplitude	NOUN
admet-2766	73	31	0.025	0.025	NUM
admet-2766	73	32	v	v	NOUN
admet-2766	73	33	,	,	PUNCT
admet-2766	73	34	and	and	CCONJ
admet-2766	73	35	admet	admet	PROPN
admet-2766	73	36	&	&	CCONJ
admet-2766	73	37	dmpk	dmpk	PROPN
admet-2766	73	38	13(3	13(3	NUM
admet-2766	73	39	)	)	PUNCT
admet-2766	73	40	(	(	PUNCT
admet-2766	73	41	2025	2025	NUM
admet-2766	73	42	)	)	PUNCT
admet-2766	73	43	2766	2766	NUM
admet-2766	73	44	crispr	crispr	ADJ
admet-2766	73	45	/	/	SYM
admet-2766	73	46	cas9	cas9	NOUN
admet-2766	73	47	biosensor	biosensor	NOUN
admet-2766	73	48	for	for	ADP
admet-2766	73	49	the	the	DET
admet-2766	73	50	detection	detection	NOUN
admet-2766	73	51	of	of	ADP
admet-2766	73	52	katg	katg	PROPN
admet-2766	73	53	gene	gene	NOUN
admet-2766	73	54	mutations	mutation	NOUN
admet-2766	73	55	doi	doi	NOUN
admet-2766	73	56	:	:	PUNCT
admet-2766	73	57	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	73	58	5	5	NUM
admet-2766	73	59	frequency	frequency	NOUN
admet-2766	73	60	25	25	NUM
admet-2766	73	61	hz	hz	NOUN
admet-2766	73	62	)	)	PUNCT
admet-2766	73	63	.	.	PUNCT
admet-2766	74	1	the	the	DET
admet-2766	74	2	resulting	result	VERB
admet-2766	74	3	ferrocene	ferrocene	ADJ
admet-2766	74	4	redox	redox	NOUN
admet-2766	74	5	current	current	NOUN
admet-2766	74	6	indicated	indicate	VERB
admet-2766	74	7	dna	dna	NOUN
admet-2766	74	8	cleavage	cleavage	NOUN
admet-2766	74	9	activity	activity	NOUN
admet-2766	74	10	,	,	PUNCT
admet-2766	74	11	with	with	ADP
admet-2766	74	12	lower	low	ADJ
admet-2766	74	13	current	current	ADJ
admet-2766	74	14	responses	response	NOUN
admet-2766	74	15	observed	observe	VERB
admet-2766	74	16	in	in	ADP
admet-2766	74	17	the	the	DET
admet-2766	74	18	presence	presence	NOUN
admet-2766	74	19	of	of	ADP
admet-2766	74	20	target	target	NOUN
admet-2766	74	21	mutations	mutation	NOUN
admet-2766	74	22	compared	compare	VERB
admet-2766	74	23	to	to	ADP
admet-2766	74	24	wild	wild	ADJ
admet-2766	74	25	-	-	PUNCT
admet-2766	74	26	type	type	NOUN
admet-2766	74	27	or	or	CCONJ
admet-2766	74	28	non	non	ADJ
admet-2766	74	29	-	-	ADJ
admet-2766	74	30	target	target	ADJ
admet-2766	74	31	sequences	sequence	NOUN
admet-2766	74	32	.	.	PUNCT
admet-2766	75	1	results	result	NOUN
admet-2766	75	2	and	and	CCONJ
admet-2766	75	3	discussion	discussion	NOUN
admet-2766	75	4	grna	grna	NOUN
admet-2766	75	5	design	design	NOUN
admet-2766	75	6	for	for	ADP
admet-2766	75	7	crispr	crispr	ADJ
admet-2766	75	8	/	/	SYM
admet-2766	75	9	cas9	cas9	NOUN
admet-2766	75	10	target	target	NOUN
admet-2766	75	11	prediction	prediction	NOUN
admet-2766	75	12	the	the	DET
admet-2766	75	13	on	on	ADP
admet-2766	75	14	-	-	PUNCT
admet-2766	75	15	target	target	NOUN
admet-2766	75	16	and	and	CCONJ
admet-2766	75	17	off	off	ADP
admet-2766	75	18	-	-	PUNCT
admet-2766	75	19	target	target	NOUN
admet-2766	75	20	scores	score	NOUN
admet-2766	75	21	are	be	AUX
admet-2766	75	22	critical	critical	ADJ
admet-2766	75	23	metrics	metric	NOUN
admet-2766	75	24	for	for	ADP
admet-2766	75	25	identifying	identify	VERB
admet-2766	75	26	optimal	optimal	ADJ
admet-2766	75	27	crispr	crispr	ADJ
admet-2766	75	28	/	/	SYM
admet-2766	75	29	cas9	cas9	NOUN
admet-2766	75	30	grna	grna	NOUN
admet-2766	75	31	candidates	candidate	NOUN
admet-2766	75	32	.	.	PUNCT
admet-2766	76	1	the	the	DET
admet-2766	76	2	on	on	ADP
admet-2766	76	3	-	-	PUNCT
admet-2766	76	4	target	target	NOUN
admet-2766	76	5	score	score	NOUN
admet-2766	76	6	measures	measure	NOUN
admet-2766	76	7	the	the	DET
admet-2766	76	8	binding	bind	VERB
admet-2766	76	9	efficiency	efficiency	NOUN
admet-2766	76	10	of	of	ADP
admet-2766	76	11	the	the	DET
admet-2766	76	12	grna	grna	NOUN
admet-2766	76	13	to	to	ADP
admet-2766	76	14	the	the	DET
admet-2766	76	15	target	target	NOUN
admet-2766	76	16	dna	dna	NOUN
admet-2766	76	17	,	,	PUNCT
admet-2766	76	18	ensuring	ensure	VERB
admet-2766	76	19	accurate	accurate	ADJ
admet-2766	76	20	cleavage	cleavage	NOUN
admet-2766	76	21	by	by	ADP
admet-2766	76	22	the	the	DET
admet-2766	76	23	cas	cas	PROPN
admet-2766	76	24	enzyme	enzyme	NOUN
admet-2766	76	25	.	.	PUNCT
admet-2766	77	1	a	a	DET
admet-2766	77	2	higher	high	ADJ
admet-2766	77	3	on	on	ADP
admet-2766	77	4	-	-	PUNCT
admet-2766	77	5	target	target	NOUN
admet-2766	77	6	score	score	NOUN
admet-2766	77	7	indicates	indicate	VERB
admet-2766	77	8	greater	great	ADJ
admet-2766	77	9	precision	precision	NOUN
admet-2766	77	10	and	and	CCONJ
admet-2766	77	11	effectiveness	effectiveness	NOUN
admet-2766	77	12	of	of	ADP
admet-2766	77	13	the	the	DET
admet-2766	77	14	grna	grna	NOUN
admet-2766	77	15	in	in	ADP
admet-2766	77	16	directing	direct	VERB
admet-2766	77	17	cas9	cas9	NOUN
admet-2766	77	18	to	to	ADP
admet-2766	77	19	the	the	DET
admet-2766	77	20	intended	intend	VERB
admet-2766	77	21	target	target	NOUN
admet-2766	77	22	.	.	PUNCT
admet-2766	78	1	in	in	ADP
admet-2766	78	2	contrast	contrast	NOUN
admet-2766	78	3	,	,	PUNCT
admet-2766	78	4	the	the	DET
admet-2766	78	5	off	off	ADP
admet-2766	78	6	-	-	PUNCT
admet-2766	78	7	target	target	NOUN
admet-2766	78	8	score	score	NOUN
admet-2766	78	9	quantifies	quantifie	NOUN
admet-2766	78	10	the	the	DET
admet-2766	78	11	likelihood	likelihood	NOUN
admet-2766	78	12	of	of	ADP
admet-2766	78	13	the	the	DET
admet-2766	78	14	grna	grna	NOUN
admet-2766	78	15	binding	bind	VERB
admet-2766	78	16	to	to	ADP
admet-2766	78	17	and	and	CCONJ
admet-2766	78	18	facilitating	facilitate	VERB
admet-2766	78	19	cleavage	cleavage	NOUN
admet-2766	78	20	of	of	ADP
admet-2766	78	21	non	non	ADJ
admet-2766	78	22	-	-	ADJ
admet-2766	78	23	target	target	ADJ
admet-2766	78	24	dna	dna	NOUN
admet-2766	78	25	.	.	PUNCT
admet-2766	79	1	a	a	DET
admet-2766	79	2	higher	high	ADJ
admet-2766	79	3	off	off	ADP
admet-2766	79	4	-	-	PUNCT
admet-2766	79	5	target	target	NOUN
admet-2766	79	6	score	score	NOUN
admet-2766	79	7	reflects	reflect	VERB
admet-2766	79	8	a	a	DET
admet-2766	79	9	reduced	reduced	ADJ
admet-2766	79	10	probability	probability	NOUN
admet-2766	79	11	of	of	ADP
admet-2766	79	12	unintended	unintended	ADJ
admet-2766	79	13	interactions	interaction	NOUN
admet-2766	79	14	,	,	PUNCT
admet-2766	79	15	minimizing	minimize	VERB
admet-2766	79	16	off	off	ADP
admet-2766	79	17	-	-	PUNCT
admet-2766	79	18	target	target	NOUN
admet-2766	79	19	effects	effect	NOUN
admet-2766	79	20	[	[	X
admet-2766	79	21	32	32	NUM
admet-2766	79	22	]	]	PUNCT
admet-2766	79	23	.	.	PUNCT
admet-2766	80	1	the	the	DET
admet-2766	80	2	algorithms	algorithm	NOUN
admet-2766	80	3	developed	develop	VERB
admet-2766	80	4	by	by	ADP
admet-2766	80	5	doench	doench	NOUN
admet-2766	80	6	et	et	PROPN
admet-2766	80	7	al	al	PROPN
admet-2766	80	8	.	.	PUNCT
admet-2766	81	1	[	[	X
admet-2766	81	2	33	33	NUM
admet-2766	81	3	]	]	PUNCT
admet-2766	81	4	and	and	CCONJ
admet-2766	81	5	hsu	hsu	PROPN
admet-2766	81	6	et	et	PROPN
admet-2766	81	7	al	al	PROPN
admet-2766	81	8	.	.	PUNCT
admet-2766	82	1	[	[	X
admet-2766	82	2	34	34	NUM
admet-2766	82	3	]	]	PUNCT
admet-2766	82	4	were	be	AUX
admet-2766	82	5	employed	employ	VERB
admet-2766	82	6	to	to	PART
admet-2766	82	7	calculate	calculate	VERB
admet-2766	82	8	the	the	DET
admet-2766	82	9	ontarget	ontarget	NOUN
admet-2766	82	10	and	and	CCONJ
admet-2766	82	11	off	off	ADP
admet-2766	82	12	-	-	PUNCT
admet-2766	82	13	target	target	NOUN
admet-2766	82	14	scores	score	NOUN
admet-2766	82	15	.	.	PUNCT
admet-2766	83	1	for	for	ADP
admet-2766	83	2	on	on	ADP
admet-2766	83	3	-	-	PUNCT
admet-2766	83	4	target	target	NOUN
admet-2766	83	5	score	score	NOUN
admet-2766	83	6	calculation	calculation	NOUN
admet-2766	83	7	,	,	PUNCT
admet-2766	83	8	factors	factor	NOUN
admet-2766	83	9	such	such	ADJ
admet-2766	83	10	as	as	ADP
admet-2766	83	11	the	the	DET
admet-2766	83	12	position	position	NOUN
admet-2766	83	13	and	and	CCONJ
admet-2766	83	14	length	length	NOUN
admet-2766	83	15	of	of	ADP
admet-2766	83	16	the	the	DET
admet-2766	83	17	grna	grna	NOUN
admet-2766	83	18	sequence	sequence	NOUN
admet-2766	83	19	,	,	PUNCT
admet-2766	83	20	the	the	DET
admet-2766	83	21	pam	pam	NOUN
admet-2766	83	22	sequence	sequence	NOUN
admet-2766	83	23	specific	specific	ADJ
admet-2766	83	24	to	to	ADP
admet-2766	83	25	the	the	DET
admet-2766	83	26	cas9	cas9	NOUN
admet-2766	83	27	enzyme	enzyme	NOUN
admet-2766	83	28	(	(	PUNCT
admet-2766	83	29	ngg	ngg	NOUN
admet-2766	83	30	for	for	ADP
admet-2766	83	31	spcas9	spcas9	NOUN
admet-2766	83	32	,	,	PUNCT
admet-2766	83	33	n	n	PRON
admet-2766	83	34	represents	represent	VERB
admet-2766	83	35	any	any	PRON
admet-2766	83	36	of	of	ADP
admet-2766	83	37	the	the	DET
admet-2766	83	38	four	four	NUM
admet-2766	83	39	nucleotide	nucleotide	ADJ
admet-2766	83	40	bases	basis	NOUN
admet-2766	83	41	)	)	PUNCT
admet-2766	83	42	,	,	PUNCT
admet-2766	83	43	and	and	CCONJ
admet-2766	83	44	the	the	DET
admet-2766	83	45	secondary	secondary	ADJ
admet-2766	83	46	structure	structure	NOUN
admet-2766	83	47	formation	formation	NOUN
admet-2766	83	48	energy	energy	NOUN
admet-2766	83	49	(	(	PUNCT
admet-2766	83	50	e.g.	e.g.	ADV
admet-2766	83	51	hairpins	hairpin	NOUN
admet-2766	83	52	)	)	PUNCT
admet-2766	83	53	in	in	ADP
admet-2766	83	54	the	the	DET
admet-2766	83	55	grna	grna	NOUN
admet-2766	83	56	that	that	PRON
admet-2766	83	57	can	can	AUX
admet-2766	83	58	affect	affect	VERB
admet-2766	83	59	cas9	cas9	NOUN
admet-2766	83	60	binding	bind	VERB
admet-2766	83	61	and	and	CCONJ
admet-2766	83	62	cleavage	cleavage	NOUN
admet-2766	83	63	efficiency	efficiency	NOUN
admet-2766	83	64	are	be	AUX
admet-2766	83	65	considered	consider	VERB
admet-2766	83	66	[	[	PUNCT
admet-2766	83	67	33	33	NUM
admet-2766	83	68	]	]	PUNCT
admet-2766	83	69	.	.	PUNCT
admet-2766	84	1	conversely	conversely	ADV
admet-2766	84	2	,	,	PUNCT
admet-2766	84	3	the	the	DET
admet-2766	84	4	off	off	ADP
admet-2766	84	5	-	-	PUNCT
admet-2766	84	6	target	target	NOUN
admet-2766	84	7	score	score	NOUN
admet-2766	84	8	is	be	AUX
admet-2766	84	9	determined	determine	VERB
admet-2766	84	10	by	by	ADP
admet-2766	84	11	factors	factor	NOUN
admet-2766	84	12	including	include	VERB
admet-2766	84	13	the	the	DET
admet-2766	84	14	presence	presence	NOUN
admet-2766	84	15	of	of	ADP
admet-2766	84	16	dna	dna	PROPN
admet-2766	84	17	sequences	sequence	NOUN
admet-2766	84	18	in	in	ADP
admet-2766	84	19	the	the	DET
admet-2766	84	20	genome	genome	NOUN
admet-2766	84	21	similar	similar	ADJ
admet-2766	84	22	to	to	ADP
admet-2766	84	23	the	the	DET
admet-2766	84	24	target	target	NOUN
admet-2766	84	25	sequence	sequence	NOUN
admet-2766	84	26	particularly	particularly	ADV
admet-2766	84	27	those	those	PRON
admet-2766	84	28	near	near	ADP
admet-2766	84	29	the	the	DET
admet-2766	84	30	pam	pam	NOUN
admet-2766	84	31	the	the	DET
admet-2766	84	32	position	position	NOUN
admet-2766	84	33	and	and	CCONJ
admet-2766	84	34	number	number	NOUN
admet-2766	84	35	of	of	ADP
admet-2766	84	36	mismatches	mismatch	NOUN
admet-2766	84	37	between	between	ADP
admet-2766	84	38	the	the	DET
admet-2766	84	39	grna	grna	NOUN
admet-2766	84	40	and	and	CCONJ
admet-2766	84	41	target	target	NOUN
admet-2766	84	42	dna	dna	NOUN
admet-2766	84	43	,	,	PUNCT
admet-2766	84	44	and	and	CCONJ
admet-2766	84	45	the	the	DET
admet-2766	84	46	location	location	NOUN
admet-2766	84	47	of	of	ADP
admet-2766	84	48	the	the	DET
admet-2766	84	49	pam	pam	NOUN
admet-2766	84	50	,	,	PUNCT
admet-2766	84	51	as	as	SCONJ
admet-2766	84	52	sequences	sequence	NOUN
admet-2766	84	53	proximal	proximal	ADJ
admet-2766	84	54	to	to	ADP
admet-2766	84	55	the	the	DET
admet-2766	84	56	pam	pam	NOUN
admet-2766	84	57	are	be	AUX
admet-2766	84	58	more	more	ADV
admet-2766	84	59	prone	prone	ADJ
admet-2766	84	60	to	to	ADP
admet-2766	84	61	off	off	ADP
admet-2766	84	62	-	-	PUNCT
admet-2766	84	63	target	target	NOUN
admet-2766	84	64	cleavage	cleavage	NOUN
admet-2766	85	1	[	[	X
admet-2766	85	2	34	34	NUM
admet-2766	85	3	]	]	PUNCT
admet-2766	85	4	.	.	PUNCT
admet-2766	86	1	the	the	DET
admet-2766	86	2	grna	grna	NOUN
admet-2766	86	3	designs	design	NOUN
admet-2766	86	4	targeting	target	VERB
admet-2766	86	5	the	the	DET
admet-2766	86	6	katg	katg	PROPN
admet-2766	86	7	gene	gene	NOUN
admet-2766	86	8	at	at	ADP
admet-2766	86	9	amino	amino	NOUN
admet-2766	86	10	acid	acid	NOUN
admet-2766	86	11	codons	codon	NOUN
admet-2766	86	12	315	315	NUM
admet-2766	86	13	are	be	AUX
admet-2766	86	14	presented	present	VERB
admet-2766	86	15	in	in	ADP
admet-2766	86	16	table	table	NOUN
admet-2766	86	17	1	1	NUM
admet-2766	86	18	.	.	PUNCT
admet-2766	87	1	this	this	DET
admet-2766	87	2	table	table	NOUN
admet-2766	87	3	illustrates	illustrate	VERB
admet-2766	87	4	that	that	SCONJ
admet-2766	87	5	codon	codon	PROPN
admet-2766	87	6	315	315	NUM
admet-2766	87	7	is	be	AUX
admet-2766	87	8	associated	associate	VERB
admet-2766	87	9	with	with	ADP
admet-2766	87	10	a	a	DET
admet-2766	87	11	specific	specific	ADJ
admet-2766	87	12	grna	grna	NOUN
admet-2766	87	13	design	design	NOUN
admet-2766	87	14	,	,	PUNCT
admet-2766	87	15	exhibiting	exhibit	VERB
admet-2766	87	16	various	various	ADJ
admet-2766	87	17	values	value	NOUN
admet-2766	87	18	for	for	ADP
admet-2766	87	19	on	on	ADP
admet-2766	87	20	-	-	PUNCT
admet-2766	87	21	target	target	NOUN
admet-2766	87	22	and	and	CCONJ
admet-2766	87	23	off	off	ADP
admet-2766	87	24	-	-	PUNCT
admet-2766	87	25	target	target	NOUN
admet-2766	87	26	scores	score	NOUN
admet-2766	87	27	.	.	PUNCT
admet-2766	88	1	table	table	NOUN
admet-2766	88	2	1	1	NUM
admet-2766	88	3	.	.	PUNCT
admet-2766	88	4	grna	grna	NOUN
admet-2766	88	5	design	design	NOUN
admet-2766	88	6	targeting	target	VERB
admet-2766	88	7	katg	katg	PROPN
admet-2766	88	8	gene	gene	NOUN
admet-2766	88	9	at	at	ADP
admet-2766	88	10	amino	amino	NOUN
admet-2766	88	11	acid	acid	NOUN
admet-2766	88	12	codon	codon	NOUN
admet-2766	88	13	position	position	NOUN
admet-2766	88	14	315	315	NUM
admet-2766	88	15	(	(	PUNCT
admet-2766	88	16	wild	wild	ADJ
admet-2766	88	17	-	-	PUNCT
admet-2766	88	18	type	type	NOUN
admet-2766	88	19	)	)	PUNCT
admet-2766	88	20	cut	cut	VERB
admet-2766	88	21	position	position	NOUN
admet-2766	88	22	strand	strand	NOUN
admet-2766	88	23	guide	guide	NOUN
admet-2766	88	24	sequence	sequence	NOUN
admet-2766	88	25	(	(	PUNCT
admet-2766	88	26	5	5	NUM
admet-2766	88	27	’	'	PUNCT
admet-2766	88	28	3	3	NUM
admet-2766	88	29	’	'	PUNCT
admet-2766	88	30	)	)	PUNCT
admet-2766	88	31	pam	pam	NOUN
admet-2766	88	32	on	on	ADP
admet-2766	88	33	-	-	PUNCT
admet-2766	88	34	target	target	NOUN
admet-2766	88	35	score	score	NOUN
admet-2766	88	36	off	off	ADP
admet-2766	88	37	-	-	PUNCT
admet-2766	88	38	target	target	NOUN
admet-2766	88	39	score	score	NOUN
admet-2766	88	40	2920	2920	NUM
admet-2766	88	41	+	+	CCONJ
admet-2766	88	42	ggtaaggacgcgatcaccag	ggtaaggacgcgatcaccag	NOUN
admet-2766	88	43	cgg	cgg	NOUN
admet-2766	88	44	68.9	68.9	NUM
admet-2766	88	45	49.4	49.4	NUM
admet-2766	88	46	2928	2928	NUM
admet-2766	88	47	+	+	CCONJ
admet-2766	88	48	cgcgatcaccagcggcatcg	cgcgatcaccagcggcatcg	VERB
admet-2766	88	49	agg	agg	PROPN
admet-2766	88	50	61.2	61.2	NUM
admet-2766	88	51	49.0	49.0	NUM
admet-2766	88	52	2925	2925	NUM
admet-2766	88	53	ccatacgacctcgatgccgc	ccatacgacctcgatgccgc	NOUN
admet-2766	88	54	tgg	tgg	NOUN
admet-2766	88	55	57.9	57.9	NUM
admet-2766	88	56	50.0	50.0	NUM
admet-2766	88	57	2936	2936	NUM
admet-2766	88	58	+	+	CCONJ
admet-2766	88	59	ccagcggcatcgaggtcgta	ccagcggcatcgaggtcgta	ADJ
admet-2766	88	60	tgg	tgg	PROPN
admet-2766	88	61	50.3	50.3	NUM
admet-2766	88	62	49.9	49.9	NUM
admet-2766	88	63	2907	2907	NUM
admet-2766	88	64	gctggtgatcgcgtccttac	gctggtgatcgcgtccttac	ADJ
admet-2766	88	65	cgg	cgg	NOUN
admet-2766	88	66	36.6	36.6	NUM
admet-2766	88	67	49.9	49.9	NUM
admet-2766	88	68	in	in	ADP
admet-2766	88	69	designing	design	VERB
admet-2766	88	70	grna	grna	NOUN
admet-2766	88	71	for	for	ADP
admet-2766	88	72	the	the	DET
admet-2766	88	73	crispr	crispr	ADJ
admet-2766	88	74	/	/	SYM
admet-2766	88	75	cas	cas	NOUN
admet-2766	88	76	system	system	NOUN
admet-2766	88	77	,	,	PUNCT
admet-2766	88	78	the	the	DET
admet-2766	88	79	relationship	relationship	NOUN
admet-2766	88	80	between	between	ADP
admet-2766	88	81	the	the	DET
admet-2766	88	82	location	location	NOUN
admet-2766	88	83	of	of	ADP
admet-2766	88	84	the	the	DET
admet-2766	88	85	mutation	mutation	NOUN
admet-2766	88	86	points	point	NOUN
admet-2766	88	87	and	and	CCONJ
admet-2766	88	88	the	the	DET
admet-2766	88	89	pam	pam	NOUN
admet-2766	88	90	sequence	sequence	NOUN
admet-2766	88	91	is	be	AUX
admet-2766	88	92	critical	critical	ADJ
admet-2766	88	93	because	because	SCONJ
admet-2766	88	94	the	the	DET
admet-2766	88	95	pam	pam	NOUN
admet-2766	88	96	is	be	AUX
admet-2766	88	97	essential	essential	ADJ
admet-2766	88	98	for	for	ADP
admet-2766	88	99	target	target	NOUN
admet-2766	88	100	recognition	recognition	NOUN
admet-2766	88	101	by	by	ADP
admet-2766	88	102	the	the	DET
admet-2766	88	103	cas	cas	PROPN
admet-2766	88	104	enzyme	enzyme	NOUN
admet-2766	88	105	.	.	PUNCT
admet-2766	89	1	if	if	SCONJ
admet-2766	89	2	the	the	DET
admet-2766	89	3	mutation	mutation	NOUN
admet-2766	89	4	point	point	NOUN
admet-2766	89	5	is	be	AUX
admet-2766	89	6	located	locate	VERB
admet-2766	89	7	too	too	ADV
admet-2766	89	8	far	far	ADV
admet-2766	89	9	from	from	ADP
admet-2766	89	10	the	the	DET
admet-2766	89	11	pam	pam	NOUN
admet-2766	89	12	(	(	PUNCT
admet-2766	89	13	e.g.	e.g.	ADV
admet-2766	89	14	more	more	ADJ
admet-2766	89	15	than	than	ADP
admet-2766	89	16	20	20	NUM
admet-2766	89	17	-	-	SYM
admet-2766	89	18	25	25	NUM
admet-2766	89	19	base	base	NOUN
admet-2766	89	20	pairs	pair	NOUN
admet-2766	89	21	)	)	PUNCT
admet-2766	89	22	,	,	PUNCT
admet-2766	89	23	the	the	DET
admet-2766	89	24	grna	grna	NOUN
admet-2766	89	25	may	may	AUX
admet-2766	89	26	not	not	PART
admet-2766	89	27	effectively	effectively	ADV
admet-2766	89	28	direct	direct	VERB
admet-2766	89	29	the	the	DET
admet-2766	89	30	cas	cas	NOUN
admet-2766	89	31	enzyme	enzyme	NOUN
admet-2766	89	32	to	to	ADP
admet-2766	89	33	the	the	DET
admet-2766	89	34	target	target	NOUN
admet-2766	89	35	because	because	SCONJ
admet-2766	89	36	the	the	DET
admet-2766	89	37	target	target	NOUN
admet-2766	89	38	sequence	sequence	NOUN
admet-2766	89	39	must	must	AUX
admet-2766	89	40	be	be	AUX
admet-2766	89	41	within	within	ADP
admet-2766	89	42	the	the	DET
admet-2766	89	43	20	20	NUM
admet-2766	89	44	nucleotides	nucleotide	NOUN
admet-2766	89	45	preceding	precede	VERB
admet-2766	89	46	the	the	DET
admet-2766	89	47	pam	pam	NOUN
admet-2766	89	48	.	.	PUNCT
admet-2766	90	1	mutations	mutation	NOUN
admet-2766	90	2	located	locate	VERB
admet-2766	90	3	close	close	ADV
admet-2766	90	4	to	to	ADP
admet-2766	90	5	the	the	DET
admet-2766	90	6	pam	pam	NOUN
admet-2766	90	7	sequence	sequence	NOUN
admet-2766	90	8	can	can	AUX
admet-2766	90	9	still	still	ADV
admet-2766	90	10	be	be	AUX
admet-2766	90	11	targeted	target	VERB
admet-2766	90	12	by	by	ADP
admet-2766	90	13	crispr	crispr	PROPN
admet-2766	90	14	/	/	SYM
admet-2766	90	15	cas	cas	PROPN
admet-2766	90	16	,	,	PUNCT
admet-2766	90	17	provided	provide	VERB
admet-2766	90	18	the	the	DET
admet-2766	90	19	pam	pam	NOUN
admet-2766	90	20	remains	remain	VERB
admet-2766	90	21	intact	intact	ADJ
admet-2766	90	22	and	and	CCONJ
admet-2766	90	23	the	the	DET
admet-2766	90	24	grna	grna	NOUN
admet-2766	90	25	is	be	AUX
admet-2766	90	26	designed	design	VERB
admet-2766	90	27	to	to	PART
admet-2766	90	28	account	account	VERB
admet-2766	90	29	for	for	ADP
admet-2766	90	30	the	the	DET
admet-2766	90	31	changes	change	NOUN
admet-2766	90	32	in	in	ADP
admet-2766	90	33	the	the	DET
admet-2766	90	34	target	target	NOUN
admet-2766	90	35	sequence	sequence	NOUN
admet-2766	90	36	[	[	X
admet-2766	90	37	35,36	35,36	NUM
admet-2766	90	38	]	]	PUNCT
admet-2766	90	39	.	.	PUNCT
admet-2766	91	1	in	in	ADP
admet-2766	91	2	crispr	crispr	NOUN
admet-2766	91	3	-	-	PUNCT
admet-2766	91	4	based	base	VERB
admet-2766	91	5	mutation	mutation	NOUN
admet-2766	91	6	detection	detection	NOUN
admet-2766	91	7	,	,	PUNCT
admet-2766	91	8	the	the	DET
admet-2766	91	9	grna	grna	NOUN
admet-2766	91	10	design	design	NOUN
admet-2766	91	11	should	should	AUX
admet-2766	91	12	utilize	utilize	VERB
admet-2766	91	13	specific	specific	ADJ
admet-2766	91	14	differences	difference	NOUN
admet-2766	91	15	between	between	ADP
admet-2766	91	16	normal	normal	ADJ
admet-2766	91	17	and	and	CCONJ
admet-2766	91	18	mutant	mutant	ADJ
admet-2766	91	19	targets	target	NOUN
admet-2766	91	20	.	.	PUNCT
admet-2766	92	1	the	the	DET
admet-2766	92	2	mutation	mutation	NOUN
admet-2766	92	3	should	should	AUX
admet-2766	92	4	be	be	AUX
admet-2766	92	5	located	locate	VERB
admet-2766	92	6	near	near	ADP
admet-2766	92	7	the	the	DET
admet-2766	92	8	3	3	NUM
admet-2766	92	9	'	'	PART
admet-2766	92	10	end	end	NOUN
admet-2766	92	11	of	of	ADP
admet-2766	92	12	the	the	DET
admet-2766	92	13	grna	grna	NOUN
admet-2766	92	14	target	target	NOUN
admet-2766	92	15	sequence	sequence	NOUN
admet-2766	92	16	(	(	PUNCT
admet-2766	92	17	before	before	ADP
admet-2766	92	18	the	the	DET
admet-2766	92	19	pam	pam	NOUN
admet-2766	92	20	)	)	PUNCT
admet-2766	92	21	,	,	PUNCT
admet-2766	92	22	as	as	SCONJ
admet-2766	92	23	this	this	DET
admet-2766	92	24	region	region	NOUN
admet-2766	92	25	is	be	AUX
admet-2766	92	26	more	more	ADV
admet-2766	92	27	sensitive	sensitive	ADJ
admet-2766	92	28	to	to	ADP
admet-2766	92	29	the	the	DET
admet-2766	92	30	recognition	recognition	NOUN
admet-2766	92	31	of	of	ADP
admet-2766	92	32	mismatched	mismatched	ADJ
admet-2766	92	33	base	base	NOUN
admet-2766	92	34	pairs	pair	NOUN
admet-2766	92	35	,	,	PUNCT
admet-2766	92	36	allowing	allow	VERB
admet-2766	92	37	crispr	crispr	NOUN
admet-2766	92	38	to	to	PART
admet-2766	92	39	more	more	ADV
admet-2766	92	40	effectively	effectively	ADV
admet-2766	92	41	distinguish	distinguish	VERB
admet-2766	92	42	between	between	ADP
admet-2766	92	43	normal	normal	ADJ
admet-2766	92	44	and	and	CCONJ
admet-2766	92	45	mutated	mutate	VERB
admet-2766	92	46	targets	target	NOUN
admet-2766	92	47	.	.	PUNCT
admet-2766	93	1	if	if	SCONJ
admet-2766	93	2	the	the	DET
admet-2766	93	3	mutation	mutation	NOUN
admet-2766	93	4	is	be	AUX
admet-2766	93	5	too	too	ADV
admet-2766	93	6	far	far	ADV
admet-2766	93	7	from	from	ADP
admet-2766	93	8	the	the	DET
admet-2766	93	9	pam	pam	NOUN
admet-2766	93	10	or	or	CCONJ
admet-2766	93	11	located	locate	VERB
admet-2766	93	12	at	at	ADP
admet-2766	93	13	the	the	DET
admet-2766	93	14	5	5	NUM
admet-2766	93	15	'	'	PART
admet-2766	93	16	end	end	NOUN
admet-2766	93	17	of	of	ADP
admet-2766	93	18	the	the	DET
admet-2766	93	19	target	target	NOUN
admet-2766	93	20	sequence	sequence	NOUN
admet-2766	93	21	,	,	PUNCT
admet-2766	93	22	the	the	DET
admet-2766	93	23	sensitivity	sensitivity	NOUN
admet-2766	93	24	to	to	ADP
admet-2766	93	25	mismatches	mismatch	NOUN
admet-2766	93	26	tends	tend	VERB
admet-2766	93	27	to	to	PART
admet-2766	93	28	decrease	decrease	VERB
admet-2766	93	29	,	,	PUNCT
admet-2766	93	30	which	which	PRON
admet-2766	93	31	may	may	AUX
admet-2766	93	32	compromise	compromise	VERB
admet-2766	93	33	the	the	DET
admet-2766	93	34	specificity	specificity	NOUN
admet-2766	93	35	of	of	ADP
admet-2766	93	36	detection	detection	NOUN
admet-2766	93	37	[	[	X
admet-2766	93	38	36	36	NUM
admet-2766	93	39	]	]	PUNCT
admet-2766	93	40	.	.	PUNCT
admet-2766	94	1	the	the	DET
admet-2766	94	2	relationship	relationship	NOUN
admet-2766	94	3	between	between	ADP
admet-2766	94	4	mutation	mutation	NOUN
admet-2766	94	5	distance	distance	NOUN
admet-2766	94	6	and	and	CCONJ
admet-2766	94	7	pam	pam	NOUN
admet-2766	94	8	sequence	sequence	NOUN
admet-2766	94	9	in	in	ADP
admet-2766	94	10	crispr	crispr	NOUN
admet-2766	94	11	/	/	SYM
admet-2766	94	12	cas9	cas9	NOUN
admet-2766	94	13	-	-	PUNCT
admet-2766	94	14	based	base	VERB
admet-2766	94	15	sensors	sensor	NOUN
admet-2766	94	16	has	have	AUX
admet-2766	94	17	been	be	AUX
admet-2766	94	18	studied	study	VERB
admet-2766	94	19	in	in	ADP
admet-2766	94	20	previous	previous	ADJ
admet-2766	94	21	research	research	NOUN
admet-2766	94	22	,	,	PUNCT
admet-2766	94	23	where	where	SCONJ
admet-2766	94	24	it	it	PRON
admet-2766	94	25	was	be	AUX
admet-2766	94	26	explained	explain	VERB
admet-2766	94	27	that	that	SCONJ
admet-2766	94	28	the	the	PRON
admet-2766	94	29	closer	close	ADJ
admet-2766	94	30	the	the	DET
admet-2766	94	31	distance	distance	NOUN
admet-2766	94	32	of	of	ADP
admet-2766	94	33	the	the	DET
admet-2766	94	34	mutation	mutation	NOUN
admet-2766	94	35	point	point	NOUN
admet-2766	94	36	to	to	ADP
admet-2766	94	37	the	the	DET
admet-2766	94	38	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	94	39	d.	d.	PROPN
admet-2766	94	40	a.	a.	PROPN
admet-2766	94	41	wulandari	wulandari	PROPN
admet-2766	94	42	et	et	PROPN
admet-2766	94	43	al	al	PROPN
admet-2766	94	44	.	.	PROPN
admet-2766	94	45	admet	admet	PROPN
admet-2766	94	46	&	&	CCONJ
admet-2766	94	47	dmpk	dmpk	PROPN
admet-2766	94	48	13(3	13(3	NUM
admet-2766	94	49	)	)	PUNCT
admet-2766	94	50	(	(	PUNCT
admet-2766	94	51	2025	2025	NUM
admet-2766	94	52	)	)	PUNCT
admet-2766	94	53	2766	2766	NUM
admet-2766	94	54	6	6	NUM
admet-2766	94	55	pam	pam	NOUN
admet-2766	94	56	,	,	PUNCT
admet-2766	94	57	the	the	PRON
admet-2766	94	58	lower	low	ADJ
admet-2766	94	59	the	the	DET
admet-2766	94	60	sensor	sensor	NOUN
admet-2766	94	61	signal	signal	NOUN
admet-2766	94	62	and	and	CCONJ
admet-2766	94	63	almost	almost	ADV
admet-2766	94	64	the	the	DET
admet-2766	94	65	same	same	ADJ
admet-2766	94	66	as	as	ADP
admet-2766	94	67	the	the	DET
admet-2766	94	68	signal	signal	NOUN
admet-2766	94	69	without	without	ADP
admet-2766	94	70	the	the	DET
admet-2766	94	71	target	target	NOUN
admet-2766	94	72	.	.	PUNCT
admet-2766	95	1	on	on	ADP
admet-2766	95	2	the	the	DET
admet-2766	95	3	other	other	ADJ
admet-2766	95	4	hand	hand	NOUN
admet-2766	95	5	,	,	PUNCT
admet-2766	95	6	the	the	DET
admet-2766	95	7	response	response	NOUN
admet-2766	95	8	will	will	AUX
admet-2766	95	9	be	be	AUX
admet-2766	95	10	nearly	nearly	ADV
admet-2766	95	11	identical	identical	ADJ
admet-2766	95	12	to	to	ADP
admet-2766	95	13	the	the	DET
admet-2766	95	14	full	full	ADJ
admet-2766	95	15	match	match	NOUN
admet-2766	95	16	target	target	NOUN
admet-2766	95	17	signal	signal	VERB
admet-2766	95	18	the	the	PRON
admet-2766	95	19	farther	far	ADV
admet-2766	95	20	the	the	DET
admet-2766	95	21	mutation	mutation	NOUN
admet-2766	95	22	site	site	NOUN
admet-2766	95	23	is	be	AUX
admet-2766	95	24	from	from	ADP
admet-2766	95	25	the	the	DET
admet-2766	95	26	sensor	sensor	NOUN
admet-2766	95	27	.	.	PUNCT
admet-2766	96	1	the	the	DET
admet-2766	96	2	optimal	optimal	ADJ
admet-2766	96	3	mutation	mutation	NOUN
admet-2766	96	4	and	and	CCONJ
admet-2766	96	5	pam	pam	NOUN
admet-2766	96	6	distance	distance	NOUN
admet-2766	96	7	that	that	PRON
admet-2766	96	8	results	result	VERB
admet-2766	96	9	in	in	ADP
admet-2766	96	10	a	a	DET
admet-2766	96	11	distinct	distinct	ADJ
admet-2766	96	12	difference	difference	NOUN
admet-2766	96	13	between	between	ADP
admet-2766	96	14	the	the	DET
admet-2766	96	15	no	no	DET
admet-2766	96	16	-	-	PUNCT
admet-2766	96	17	target	target	NOUN
admet-2766	96	18	and	and	CCONJ
admet-2766	96	19	target	target	NOUN
admet-2766	96	20	-	-	PUNCT
admet-2766	96	21	present	present	ADJ
admet-2766	96	22	signals	signal	NOUN
admet-2766	96	23	is	be	AUX
admet-2766	96	24	at	at	ADP
admet-2766	96	25	a	a	DET
admet-2766	96	26	distance	distance	NOUN
admet-2766	96	27	of	of	ADP
admet-2766	96	28	10	10	NUM
admet-2766	96	29	bases	basis	NOUN
admet-2766	96	30	[	[	X
admet-2766	96	31	37,38	37,38	NOUN
admet-2766	96	32	]	]	PUNCT
admet-2766	96	33	.	.	PUNCT
admet-2766	97	1	mutations	mutation	NOUN
admet-2766	97	2	in	in	ADP
admet-2766	97	3	the	the	DET
admet-2766	97	4	katg	katg	PROPN
admet-2766	97	5	gene	gene	NOUN
admet-2766	97	6	can	can	AUX
admet-2766	97	7	be	be	AUX
admet-2766	97	8	identified	identify	VERB
admet-2766	97	9	by	by	ADP
admet-2766	97	10	designing	design	VERB
admet-2766	97	11	grna	grna	NOUN
admet-2766	97	12	specifically	specifically	ADV
admet-2766	97	13	targeting	target	VERB
admet-2766	97	14	the	the	DET
admet-2766	97	15	mutation	mutation	NOUN
admet-2766	97	16	site	site	NOUN
admet-2766	97	17	.	.	PUNCT
admet-2766	98	1	the	the	DET
admet-2766	98	2	mutation	mutation	NOUN
admet-2766	98	3	-	-	PUNCT
admet-2766	98	4	specific	specific	ADJ
admet-2766	98	5	adjusted	adjust	VERB
admet-2766	98	6	grna	grna	NOUN
admet-2766	98	7	designs	design	NOUN
admet-2766	98	8	for	for	ADP
admet-2766	98	9	the	the	DET
admet-2766	98	10	katg	katg	PROPN
admet-2766	98	11	gene	gene	NOUN
admet-2766	98	12	are	be	AUX
admet-2766	98	13	provided	provide	VERB
admet-2766	98	14	in	in	ADP
admet-2766	98	15	table	table	NOUN
admet-2766	98	16	2	2	NUM
admet-2766	98	17	.	.	PUNCT
admet-2766	99	1	in	in	ADP
admet-2766	99	2	biosensor	biosensor	NOUN
admet-2766	99	3	applications	application	NOUN
admet-2766	99	4	,	,	PUNCT
admet-2766	99	5	the	the	DET
admet-2766	99	6	distance	distance	NOUN
admet-2766	99	7	between	between	ADP
admet-2766	99	8	the	the	DET
admet-2766	99	9	mutation	mutation	NOUN
admet-2766	99	10	site	site	NOUN
admet-2766	99	11	and	and	CCONJ
admet-2766	99	12	the	the	DET
admet-2766	99	13	protospacer	protospacer	NOUN
admet-2766	99	14	adjacent	adjacent	ADJ
admet-2766	99	15	motif	motif	NOUN
admet-2766	99	16	(	(	PUNCT
admet-2766	99	17	pam	pam	NOUN
admet-2766	99	18	)	)	PUNCT
admet-2766	99	19	sequence	sequence	NOUN
admet-2766	99	20	is	be	AUX
admet-2766	99	21	a	a	DET
admet-2766	99	22	critical	critical	ADJ
admet-2766	99	23	factor	factor	NOUN
admet-2766	99	24	in	in	ADP
admet-2766	99	25	grna	grna	NOUN
admet-2766	99	26	design	design	NOUN
admet-2766	99	27	.	.	PUNCT
admet-2766	100	1	accordingly	accordingly	ADV
admet-2766	100	2	,	,	PUNCT
admet-2766	100	3	the	the	DET
admet-2766	100	4	selected	select	VERB
admet-2766	100	5	grna	grna	NOUN
admet-2766	100	6	targets	target	NOUN
admet-2766	100	7	codon	codon	VERB
admet-2766	100	8	315	315	NUM
admet-2766	100	9	of	of	ADP
admet-2766	100	10	the	the	DET
admet-2766	100	11	katg	katg	PROPN
admet-2766	100	12	gene	gene	NOUN
admet-2766	100	13	,	,	PUNCT
admet-2766	100	14	which	which	PRON
admet-2766	100	15	exhibits	exhibit	VERB
admet-2766	100	16	high	high	ADJ
admet-2766	100	17	on	on	ADP
admet-2766	100	18	-	-	PUNCT
admet-2766	100	19	target	target	NOUN
admet-2766	100	20	and	and	CCONJ
admet-2766	100	21	off	off	ADP
admet-2766	100	22	-	-	PUNCT
admet-2766	100	23	target	target	NOUN
admet-2766	100	24	scores	score	NOUN
admet-2766	100	25	of	of	ADP
admet-2766	100	26	61.2	61.2	NUM
admet-2766	100	27	and	and	CCONJ
admet-2766	100	28	49.0	49.0	NUM
admet-2766	100	29	,	,	PUNCT
admet-2766	100	30	respectively	respectively	ADV
admet-2766	100	31	.	.	PUNCT
admet-2766	101	1	the	the	DET
admet-2766	101	2	most	most	ADV
admet-2766	101	3	common	common	ADJ
admet-2766	101	4	mutation	mutation	NOUN
admet-2766	101	5	at	at	ADP
admet-2766	101	6	this	this	DET
admet-2766	101	7	codon	codon	NOUN
admet-2766	101	8	involves	involve	VERB
admet-2766	101	9	a	a	DET
admet-2766	101	10	nucleotide	nucleotide	NOUN
admet-2766	101	11	substitution	substitution	NOUN
admet-2766	101	12	from	from	ADP
admet-2766	101	13	agc	agc	PROPN
admet-2766	101	14	to	to	ADP
admet-2766	101	15	acc	acc	PROPN
admet-2766	101	16	,	,	PUNCT
admet-2766	101	17	located	locate	VERB
admet-2766	101	18	7	7	NUM
admet-2766	101	19	bases	basis	NOUN
admet-2766	101	20	from	from	ADP
admet-2766	101	21	the	the	DET
admet-2766	101	22	pam	pam	NOUN
admet-2766	101	23	site	site	PROPN
admet-2766	101	24	.	.	PUNCT
admet-2766	102	1	figure	figure	VERB
admet-2766	102	2	2	2	NUM
admet-2766	102	3	presents	present	VERB
admet-2766	102	4	the	the	DET
admet-2766	102	5	grna	grna	NOUN
admet-2766	102	6	candidate	candidate	NOUN
admet-2766	102	7	mechanism	mechanism	NOUN
admet-2766	102	8	for	for	ADP
admet-2766	102	9	the	the	DET
admet-2766	102	10	katg	katg	PROPN
admet-2766	102	11	gene	gene	NOUN
admet-2766	102	12	,	,	PUNCT
admet-2766	102	13	targeting	target	VERB
admet-2766	102	14	the	the	DET
admet-2766	102	15	cleavage	cleavage	NOUN
admet-2766	102	16	site	site	NOUN
admet-2766	102	17	at	at	ADP
admet-2766	102	18	position	position	NOUN
admet-2766	102	19	2928	2928	NUM
admet-2766	102	20	with	with	ADP
admet-2766	102	21	an	an	DET
admet-2766	102	22	agg	agg	PROPN
admet-2766	102	23	recognition	recognition	NOUN
admet-2766	102	24	sequence	sequence	NOUN
admet-2766	102	25	.	.	PUNCT
admet-2766	103	1	table	table	NOUN
admet-2766	103	2	2	2	NUM
admet-2766	103	3	.	.	PUNCT
admet-2766	103	4	grna	grna	NOUN
admet-2766	103	5	design	design	NOUN
admet-2766	103	6	targeting	target	VERB
admet-2766	103	7	katg	katg	PROPN
admet-2766	103	8	gene	gene	NOUN
admet-2766	103	9	frequent	frequent	ADJ
admet-2766	103	10	mutation	mutation	NOUN
admet-2766	103	11	at	at	ADP
admet-2766	103	12	amino	amino	NOUN
admet-2766	103	13	acid	acid	NOUN
admet-2766	103	14	codon	codon	NOUN
admet-2766	103	15	position	position	NOUN
admet-2766	103	16	315	315	NUM
admet-2766	103	17	nucleotide	nucleotide	NOUN
admet-2766	103	18	change	change	NOUN
admet-2766	103	19	amino	amino	NOUN
admet-2766	103	20	acid	acid	NOUN
admet-2766	103	21	change	change	NOUN
admet-2766	103	22	cut	cut	VERB
admet-2766	103	23	position	position	NOUN
admet-2766	103	24	strand	strand	NOUN
admet-2766	103	25	guide	guide	NOUN
admet-2766	103	26	sequence	sequence	NOUN
admet-2766	103	27	mutation	mutation	NOUN
admet-2766	103	28	(	(	PUNCT
admet-2766	103	29	5	5	NUM
admet-2766	103	30	’	’	SYM
admet-2766	103	31	3	3	NUM
admet-2766	103	32	’	'	PUNCT
admet-2766	103	33	)	)	PUNCT
admet-2766	103	34	pam	pam	NOUN
admet-2766	103	35	on	on	ADP
admet-2766	103	36	-	-	PUNCT
admet-2766	103	37	target	target	NOUN
admet-2766	103	38	score	score	NOUN
admet-2766	103	39	off	off	ADP
admet-2766	103	40	-	-	PUNCT
admet-2766	103	41	target	target	NOUN
admet-2766	103	42	score	score	NOUN
admet-2766	103	43	mutation	mutation	NOUN
admet-2766	103	44	distance	distance	NOUN
admet-2766	103	45	with	with	ADP
admet-2766	103	46	pam	pam	PROPN
admet-2766	103	47	agc	agc	PROPN
admet-2766	103	48	→	→	SYM
admet-2766	103	49	acc	acc	PROPN
admet-2766	103	50	ser	ser	NOUN
admet-2766	103	51	→	→	SYM
admet-2766	103	52	thr	thr	PROPN
admet-2766	103	53	2920	2920	NUM
admet-2766	103	54	+	+	CCONJ
admet-2766	103	55	ggtaaggacgcgatcaccac	ggtaaggacgcgatcaccac	PROPN
admet-2766	103	56	cgg	cgg	NOUN
admet-2766	103	57	68.9	68.9	NUM
admet-2766	103	58	49.4	49.4	NUM
admet-2766	103	59	1	1	NUM
admet-2766	103	60	base	base	NOUN
admet-2766	103	61	agc	agc	PROPN
admet-2766	103	62	→	→	SYM
admet-2766	103	63	aac	aac	NOUN
admet-2766	103	64	ser	ser	NOUN
admet-2766	103	65	→	→	SYM
admet-2766	103	66	asn	asn	PROPN
admet-2766	103	67	ggtaaggacgcgatcaccaa	ggtaaggacgcgatcaccaa	NOUN
admet-2766	103	68	1	1	NUM
admet-2766	103	69	base	base	NOUN
admet-2766	103	70	agc	agc	PROPN
admet-2766	103	71	→	→	SYM
admet-2766	103	72	atc	atc	NOUN
admet-2766	103	73	ser	ser	NOUN
admet-2766	103	74	→	→	PUNCT
admet-2766	103	75	ile	ile	PROPN
admet-2766	103	76	ggtaaggacgcgatcaccat	ggtaaggacgcgatcaccat	NOUN
admet-2766	103	77	1base	1base	NUM
admet-2766	103	78	agc	agc	PROPN
admet-2766	103	79	→	→	SYM
admet-2766	103	80	aga	aga	NOUN
admet-2766	103	81	ser	ser	NOUN
admet-2766	103	82	→	→	SYM
admet-2766	103	83	arg	arg	NOUN
admet-2766	103	84	agc	agc	PROPN
admet-2766	103	85	→	→	SYM
admet-2766	103	86	acc	acc	PROPN
admet-2766	103	87	ser	ser	NOUN
admet-2766	103	88	→	→	SYM
admet-2766	103	89	thr	thr	PROPN
admet-2766	103	90	2928	2928	NUM
admet-2766	103	91	+	+	CCONJ
admet-2766	103	92	cgcgatcaccaccggcatcg	cgcgatcaccaccggcatcg	PROPN
admet-2766	103	93	agg	agg	PROPN
admet-2766	103	94	61.2	61.2	NUM
admet-2766	103	95	49.0	49.0	NUM
admet-2766	103	96	8	8	NUM
admet-2766	103	97	bases	basis	NOUN
admet-2766	103	98	agc	agc	PROPN
admet-2766	103	99	→	→	SYM
admet-2766	103	100	aac	aac	NOUN
admet-2766	103	101	ser	ser	NOUN
admet-2766	103	102	→	→	PUNCT
admet-2766	103	103	asn	asn	PROPN
admet-2766	103	104	cgcgatcaccaacggcatcg	cgcgatcaccaacggcatcg	VERB
admet-2766	103	105	8	8	NUM
admet-2766	103	106	bases	basis	NOUN
admet-2766	103	107	agc	agc	PROPN
admet-2766	103	108	→	→	SYM
admet-2766	103	109	atc	atc	NOUN
admet-2766	103	110	ser	ser	NOUN
admet-2766	103	111	→	→	PUNCT
admet-2766	103	112	ile	ile	PROPN
admet-2766	103	113	cgcgatcaccatcggcatcg	cgcgatcaccatcggcatcg	NOUN
admet-2766	103	114	8	8	NUM
admet-2766	103	115	bases	basis	NOUN
admet-2766	103	116	agc	agc	PROPN
admet-2766	103	117	→	→	SYM
admet-2766	103	118	aga	aga	NOUN
admet-2766	103	119	ser	ser	NOUN
admet-2766	103	120	→	→	SYM
admet-2766	103	121	arg	arg	NOUN
admet-2766	103	122	cgcgatcaccagaggcatcg	cgcgatcaccagaggcatcg	NOUN
admet-2766	103	123	7	7	NUM
admet-2766	103	124	bases	basis	NOUN
admet-2766	103	125	agc	agc	PROPN
admet-2766	103	126	→	→	SYM
admet-2766	103	127	acc	acc	PROPN
admet-2766	103	128	ser	ser	NOUN
admet-2766	103	129	→	→	SYM
admet-2766	103	130	thr	thr	PROPN
admet-2766	103	131	2925	2925	NUM
admet-2766	103	132	ccatacgacctcgatgccgg	ccatacgacctcgatgccgg	NOUN
admet-2766	103	133	tgg	tgg	NOUN
admet-2766	103	134	57.9	57.9	NUM
admet-2766	103	135	50.0	50.0	NUM
admet-2766	103	136	16	16	NUM
admet-2766	103	137	bases	basis	NOUN
admet-2766	103	138	agc	agc	PROPN
admet-2766	103	139	→	→	SYM
admet-2766	103	140	aac	aac	NOUN
admet-2766	103	141	ser	ser	NOUN
admet-2766	103	142	→	→	SYM
admet-2766	103	143	asn	asn	PROPN
admet-2766	103	144	ccatacgacctcgatgccgt	ccatacgacctcgatgccgt	PROPN
admet-2766	103	145	16	16	NUM
admet-2766	103	146	bases	basis	NOUN
admet-2766	103	147	agc	agc	PROPN
admet-2766	103	148	→	→	SYM
admet-2766	103	149	atc	atc	NOUN
admet-2766	103	150	ser	ser	NOUN
admet-2766	103	151	→	→	SYM
admet-2766	103	152	ile	ile	PROPN
admet-2766	103	153	ccatacgacctcgatgccga	ccatacgacctcgatgccga	VERB
admet-2766	103	154	16	16	NUM
admet-2766	103	155	bases	basis	NOUN
admet-2766	103	156	agc	agc	PROPN
admet-2766	103	157	→	→	SYM
admet-2766	103	158	aga	aga	PROPN
admet-2766	103	159	ser	ser	NOUN
admet-2766	103	160	→	→	SYM
admet-2766	103	161	arg	arg	NOUN
admet-2766	103	162	ccatacgacctcgatgcctc	ccatacgacctcgatgcctc	NOUN
admet-2766	103	163	15	15	NUM
admet-2766	103	164	bases	basis	NOUN
admet-2766	103	165	agc	agc	PROPN
admet-2766	103	166	→	→	SYM
admet-2766	103	167	acc	acc	PROPN
admet-2766	103	168	ser	ser	NOUN
admet-2766	103	169	→	→	SYM
admet-2766	103	170	thr	thr	PROPN
admet-2766	103	171	2936	2936	NUM
admet-2766	103	172	+	+	CCONJ
admet-2766	103	173	ccaccggcatcgaggtcgta	ccaccggcatcgaggtcgta	ADJ
admet-2766	103	174	tgg	tgg	PROPN
admet-2766	103	175	50.3	50.3	NUM
admet-2766	103	176	49.9	49.9	NUM
admet-2766	103	177	16	16	NUM
admet-2766	103	178	bases	basis	NOUN
admet-2766	103	179	agc	agc	PROPN
admet-2766	103	180	→	→	SYM
admet-2766	103	181	aac	aac	NOUN
admet-2766	103	182	ser	ser	NOUN
admet-2766	103	183	→	→	PUNCT
admet-2766	103	184	asn	asn	PROPN
admet-2766	103	185	ccaacggcatcgaggtcgta	ccaacggcatcgaggtcgta	VERB
admet-2766	103	186	16	16	NUM
admet-2766	103	187	bases	basis	NOUN
admet-2766	103	188	agc	agc	PROPN
admet-2766	103	189	→	→	SYM
admet-2766	103	190	atc	atc	NOUN
admet-2766	103	191	ser	ser	NOUN
admet-2766	103	192	→	→	PUNCT
admet-2766	103	193	ile	ile	PROPN
admet-2766	103	194	ccatcggcatcgaggtcgta	ccatcggcatcgaggtcgta	PROPN
admet-2766	103	195	16	16	NUM
admet-2766	103	196	bases	basis	NOUN
admet-2766	103	197	agc	agc	PROPN
admet-2766	103	198	→	→	SYM
admet-2766	103	199	aga	aga	PROPN
admet-2766	103	200	ser	ser	NOUN
admet-2766	103	201	→	→	PROPN
admet-2766	103	202	arg	arg	NOUN
admet-2766	103	203	ccagaggcatcgaggtcgta	ccagaggcatcgaggtcgta	ADJ
admet-2766	103	204	15	15	NUM
admet-2766	103	205	bases	basis	NOUN
admet-2766	103	206	agc	agc	PROPN
admet-2766	103	207	→	→	SYM
admet-2766	103	208	acc	acc	PROPN
admet-2766	103	209	ser	ser	NOUN
admet-2766	103	210	→	→	SYM
admet-2766	103	211	thr	thr	PROPN
admet-2766	103	212	2907	2907	NUM
admet-2766	103	213	ggtggtgatcgcgtccttac	ggtggtgatcgcgtccttac	NOUN
admet-2766	103	214	cgg	cgg	NOUN
admet-2766	103	215	36.6	36.6	NUM
admet-2766	103	216	49.9	49.9	NUM
admet-2766	103	217	1	1	NUM
admet-2766	103	218	base	base	NOUN
admet-2766	103	219	agc	agc	PROPN
admet-2766	103	220	→	→	SYM
admet-2766	103	221	aac	aac	NOUN
admet-2766	103	222	ser	ser	NOUN
admet-2766	103	223	→	→	PUNCT
admet-2766	103	224	asn	asn	PROPN
admet-2766	103	225	gttggtgatcgcgtccttac	gttggtgatcgcgtccttac	PROPN
admet-2766	103	226	1	1	NUM
admet-2766	103	227	base	base	NOUN
admet-2766	103	228	agc	agc	PROPN
admet-2766	103	229	→	→	SYM
admet-2766	103	230	atc	atc	NOUN
admet-2766	103	231	ser	ser	NOUN
admet-2766	103	232	→	→	SYM
admet-2766	103	233	ile	ile	PROPN
admet-2766	103	234	gatggtgatcgcgtccttac	gatggtgatcgcgtccttac	NOUN
admet-2766	103	235	1	1	NUM
admet-2766	103	236	base	base	NOUN
admet-2766	103	237	agc	agc	PROPN
admet-2766	103	238	→	→	SYM
admet-2766	103	239	aga	aga	NOUN
admet-2766	103	240	ser	ser	NOUN
admet-2766	103	241	→	→	PROPN
admet-2766	103	242	arg	arg	VERB
admet-2766	103	243	tctggtgatcgcgtccttac	tctggtgatcgcgtccttac	PROPN
admet-2766	103	244	0	0	NUM
admet-2766	103	245	bases	basis	NOUN
admet-2766	103	246	figure	figure	VERB
admet-2766	103	247	2	2	NUM
admet-2766	103	248	.	.	PUNCT
admet-2766	104	1	the	the	DET
admet-2766	104	2	illustration	illustration	NOUN
admet-2766	104	3	of	of	ADP
admet-2766	104	4	grna	grna	NOUN
admet-2766	104	5	targeting	target	VERB
admet-2766	104	6	katg	katg	PROPN
admet-2766	104	7	gene	gene	NOUN
admet-2766	104	8	at	at	ADP
admet-2766	104	9	codon	codon	PROPN
admet-2766	104	10	315	315	NUM
admet-2766	104	11	with	with	ADP
admet-2766	104	12	the	the	DET
admet-2766	104	13	pam	pam	NOUN
admet-2766	104	14	sequence	sequence	PROPN
admet-2766	104	15	agg	agg	PROPN
admet-2766	104	16	to	to	PART
admet-2766	104	17	verify	verify	VERB
admet-2766	104	18	the	the	DET
admet-2766	104	19	specificity	specificity	NOUN
admet-2766	104	20	and	and	CCONJ
admet-2766	104	21	effectiveness	effectiveness	NOUN
admet-2766	104	22	of	of	ADP
admet-2766	104	23	the	the	DET
admet-2766	104	24	selected	select	VERB
admet-2766	104	25	grna	grna	NOUN
admet-2766	104	26	against	against	ADP
admet-2766	104	27	the	the	DET
admet-2766	104	28	mutant	mutant	ADJ
admet-2766	104	29	target	target	NOUN
admet-2766	104	30	dna	dna	PROPN
admet-2766	104	31	,	,	PUNCT
admet-2766	104	32	an	an	DET
admet-2766	104	33	electrochemical	electrochemical	ADJ
admet-2766	104	34	biosensor	biosensor	NOUN
admet-2766	104	35	assay	assay	NOUN
admet-2766	104	36	was	be	AUX
admet-2766	104	37	conducted	conduct	VERB
admet-2766	104	38	.	.	PUNCT
admet-2766	105	1	this	this	DET
admet-2766	105	2	test	test	NOUN
admet-2766	105	3	aimed	aim	VERB
admet-2766	105	4	to	to	PART
admet-2766	105	5	confirm	confirm	VERB
admet-2766	105	6	that	that	SCONJ
admet-2766	105	7	the	the	DET
admet-2766	105	8	grna	grna	NOUN
admet-2766	105	9	can	can	AUX
admet-2766	105	10	selectively	selectively	ADV
admet-2766	105	11	admet	admet	PROPN
admet-2766	105	12	&	&	CCONJ
admet-2766	105	13	dmpk	dmpk	PROPN
admet-2766	105	14	13(3	13(3	NUM
admet-2766	105	15	)	)	PUNCT
admet-2766	105	16	(	(	PUNCT
admet-2766	105	17	2025	2025	NUM
admet-2766	105	18	)	)	PUNCT
admet-2766	105	19	2766	2766	NUM
admet-2766	105	20	crispr	crispr	ADJ
admet-2766	105	21	/	/	SYM
admet-2766	105	22	cas9	cas9	NOUN
admet-2766	105	23	biosensor	biosensor	NOUN
admet-2766	105	24	for	for	ADP
admet-2766	105	25	the	the	DET
admet-2766	105	26	detection	detection	NOUN
admet-2766	105	27	of	of	ADP
admet-2766	105	28	katg	katg	PROPN
admet-2766	105	29	gene	gene	NOUN
admet-2766	105	30	mutations	mutation	NOUN
admet-2766	105	31	doi	doi	NOUN
admet-2766	105	32	:	:	PUNCT
admet-2766	105	33	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	X
admet-2766	105	34	7	7	NUM
admet-2766	105	35	bind	bind	VERB
admet-2766	105	36	and	and	CCONJ
admet-2766	105	37	induce	induce	VERB
admet-2766	105	38	cleavage	cleavage	NOUN
admet-2766	105	39	at	at	ADP
admet-2766	105	40	the	the	DET
admet-2766	105	41	mutated	mutate	VERB
admet-2766	105	42	dna	dna	PROPN
admet-2766	105	43	site	site	NOUN
admet-2766	105	44	,	,	PUNCT
admet-2766	105	45	and	and	CCONJ
admet-2766	105	46	to	to	PART
admet-2766	105	47	prove	prove	VERB
admet-2766	105	48	that	that	SCONJ
admet-2766	105	49	this	this	DET
admet-2766	105	50	concept	concept	NOUN
admet-2766	105	51	,	,	PUNCT
admet-2766	105	52	combined	combine	VERB
admet-2766	105	53	with	with	ADP
admet-2766	105	54	an	an	DET
admet-2766	105	55	electrochemical	electrochemical	ADJ
admet-2766	105	56	biosensor	biosensor	NOUN
admet-2766	105	57	system	system	NOUN
admet-2766	105	58	,	,	PUNCT
admet-2766	105	59	could	could	AUX
admet-2766	105	60	detect	detect	VERB
admet-2766	105	61	mdr	mdr	PROPN
admet-2766	105	62	-	-	NOUN
admet-2766	105	63	tb	tb	NOUN
admet-2766	105	64	quantitatively	quantitatively	ADV
admet-2766	105	65	and	and	CCONJ
admet-2766	105	66	could	could	AUX
admet-2766	105	67	differentiate	differentiate	VERB
admet-2766	105	68	the	the	DET
admet-2766	105	69	signal	signal	NOUN
admet-2766	105	70	from	from	ADP
admet-2766	105	71	the	the	DET
admet-2766	105	72	non	non	ADJ
admet-2766	105	73	-	-	ADJ
admet-2766	105	74	mutated	mutated	ADJ
admet-2766	105	75	tb	tb	NOUN
admet-2766	105	76	.	.	PUNCT
admet-2766	106	1	additionally	additionally	ADV
admet-2766	106	2	,	,	PUNCT
admet-2766	106	3	the	the	DET
admet-2766	106	4	electrochemical	electrochemical	ADJ
admet-2766	106	5	biosensor	biosensor	NOUN
admet-2766	106	6	enabled	enable	VERB
admet-2766	106	7	real	real	ADJ
admet-2766	106	8	-	-	PUNCT
admet-2766	106	9	time	time	NOUN
admet-2766	106	10	monitoring	monitoring	NOUN
admet-2766	106	11	of	of	ADP
admet-2766	106	12	the	the	DET
admet-2766	106	13	grna	grna	NOUN
admet-2766	106	14	-	-	PUNCT
admet-2766	106	15	target	target	NOUN
admet-2766	106	16	interaction	interaction	NOUN
admet-2766	106	17	,	,	PUNCT
admet-2766	106	18	providing	provide	VERB
admet-2766	106	19	valuable	valuable	ADJ
admet-2766	106	20	insights	insight	NOUN
admet-2766	106	21	into	into	ADP
admet-2766	106	22	the	the	DET
admet-2766	106	23	efficiency	efficiency	NOUN
admet-2766	106	24	of	of	ADP
admet-2766	106	25	the	the	DET
admet-2766	106	26	cas9	cas9	NOUN
admet-2766	106	27	-	-	PUNCT
admet-2766	106	28	mediated	mediate	VERB
admet-2766	106	29	dna	dna	NOUN
admet-2766	106	30	cutting	cut	VERB
admet-2766	106	31	process	process	NOUN
admet-2766	106	32	.	.	PUNCT
admet-2766	107	1	the	the	DET
admet-2766	107	2	integration	integration	NOUN
admet-2766	107	3	of	of	ADP
admet-2766	107	4	this	this	DET
admet-2766	107	5	approach	approach	NOUN
admet-2766	107	6	offers	offer	VERB
admet-2766	107	7	a	a	DET
admet-2766	107	8	rapid	rapid	ADJ
admet-2766	107	9	,	,	PUNCT
admet-2766	107	10	sensitive	sensitive	ADJ
admet-2766	107	11	,	,	PUNCT
admet-2766	107	12	and	and	CCONJ
admet-2766	107	13	reliable	reliable	ADJ
admet-2766	107	14	method	method	NOUN
admet-2766	107	15	for	for	ADP
admet-2766	107	16	assessing	assess	VERB
admet-2766	107	17	grna	grna	NOUN
admet-2766	107	18	performance	performance	NOUN
admet-2766	107	19	,	,	PUNCT
admet-2766	107	20	which	which	PRON
admet-2766	107	21	could	could	AUX
admet-2766	107	22	have	have	VERB
admet-2766	107	23	significant	significant	ADJ
admet-2766	107	24	implications	implication	NOUN
admet-2766	107	25	for	for	ADP
admet-2766	107	26	diagnostic	diagnostic	ADJ
admet-2766	107	27	applications	application	NOUN
admet-2766	107	28	.	.	PUNCT
admet-2766	108	1	spce	spce	PROPN
admet-2766	108	2	modification	modification	NOUN
admet-2766	108	3	with	with	ADP
admet-2766	108	4	aunps	aunps	PROPN
admet-2766	108	5	spce	spce	PROPN
admet-2766	108	6	were	be	AUX
admet-2766	108	7	pretreated	pretreate	VERB
admet-2766	108	8	with	with	ADP
admet-2766	108	9	sulfuric	sulfuric	ADJ
admet-2766	108	10	acid	acid	NOUN
admet-2766	108	11	(	(	PUNCT
admet-2766	108	12	h2so4	h2so4	PROPN
admet-2766	108	13	)	)	PUNCT
admet-2766	108	14	using	use	VERB
admet-2766	108	15	cyclic	cyclic	ADJ
admet-2766	108	16	voltammetry	voltammetry	NOUN
admet-2766	108	17	(	(	PUNCT
admet-2766	108	18	cv	cv	PROPN
admet-2766	108	19	)	)	PUNCT
admet-2766	108	20	to	to	PART
admet-2766	108	21	remove	remove	VERB
admet-2766	108	22	organic	organic	ADJ
admet-2766	108	23	binders	binder	NOUN
admet-2766	108	24	and	and	CCONJ
admet-2766	108	25	surface	surface	NOUN
admet-2766	108	26	contaminants	contaminant	NOUN
admet-2766	108	27	,	,	PUNCT
admet-2766	108	28	introduce	introduce	VERB
admet-2766	108	29	oxygen	oxygen	NOUN
admet-2766	108	30	-	-	PUNCT
admet-2766	108	31	containing	contain	VERB
admet-2766	108	32	functional	functional	ADJ
admet-2766	108	33	groups	group	NOUN
admet-2766	108	34	(	(	PUNCT
admet-2766	108	35	e.g.	e.g.	ADV
admet-2766	108	36	hydroxyl	hydroxyl	NOUN
admet-2766	108	37	and	and	CCONJ
admet-2766	108	38	carbonyl	carbonyl	NOUN
admet-2766	108	39	)	)	PUNCT
admet-2766	108	40	,	,	PUNCT
admet-2766	108	41	and	and	CCONJ
admet-2766	108	42	increase	increase	VERB
admet-2766	108	43	the	the	DET
admet-2766	108	44	electroactive	electroactive	ADJ
admet-2766	108	45	surface	surface	NOUN
admet-2766	108	46	area	area	NOUN
admet-2766	108	47	to	to	PART
admet-2766	108	48	improve	improve	VERB
admet-2766	108	49	the	the	DET
admet-2766	108	50	electrochemical	electrochemical	ADJ
admet-2766	108	51	performance	performance	NOUN
admet-2766	108	52	of	of	ADP
admet-2766	108	53	the	the	DET
admet-2766	108	54	electrode	electrode	NOUN
admet-2766	108	55	[	[	X
admet-2766	108	56	39	39	NUM
admet-2766	108	57	]	]	PUNCT
admet-2766	108	58	.	.	PUNCT
admet-2766	109	1	following	follow	VERB
admet-2766	109	2	the	the	DET
admet-2766	109	3	pretreatment	pretreatment	NOUN
admet-2766	109	4	process	process	NOUN
admet-2766	109	5	,	,	PUNCT
admet-2766	109	6	the	the	DET
admet-2766	109	7	spce	spce	NOUN
admet-2766	109	8	were	be	AUX
admet-2766	109	9	modified	modify	VERB
admet-2766	109	10	with	with	ADP
admet-2766	109	11	aunps	aunps	PROPN
admet-2766	109	12	via	via	ADP
admet-2766	109	13	electrochemical	electrochemical	ADJ
admet-2766	109	14	deposition	deposition	NOUN
admet-2766	109	15	.	.	PUNCT
admet-2766	110	1	his	his	PRON
admet-2766	110	2	method	method	NOUN
admet-2766	110	3	offers	offer	VERB
admet-2766	110	4	precise	precise	ADJ
admet-2766	110	5	control	control	NOUN
admet-2766	110	6	over	over	ADP
admet-2766	110	7	key	key	ADJ
admet-2766	110	8	parameters	parameter	NOUN
admet-2766	110	9	,	,	PUNCT
admet-2766	110	10	including	include	VERB
admet-2766	110	11	deposition	deposition	NOUN
admet-2766	110	12	time	time	NOUN
admet-2766	110	13	,	,	PUNCT
admet-2766	110	14	applied	apply	VERB
admet-2766	110	15	potential	potential	NOUN
admet-2766	110	16	,	,	PUNCT
admet-2766	110	17	and	and	CCONJ
admet-2766	110	18	metal	metal	NOUN
admet-2766	110	19	ion	ion	NOUN
admet-2766	110	20	concentration	concentration	NOUN
admet-2766	110	21	.	.	PUNCT
admet-2766	111	1	in	in	ADP
admet-2766	111	2	this	this	DET
admet-2766	111	3	study	study	NOUN
admet-2766	111	4	,	,	PUNCT
admet-2766	111	5	electrodeposition	electrodeposition	NOUN
admet-2766	111	6	was	be	AUX
admet-2766	111	7	performed	perform	VERB
admet-2766	111	8	using	use	VERB
admet-2766	111	9	the	the	DET
admet-2766	111	10	chronoamperometry	chronoamperometry	NOUN
admet-2766	111	11	(	(	PUNCT
admet-2766	111	12	ca	ca	NOUN
admet-2766	111	13	)	)	PUNCT
admet-2766	111	14	technique	technique	NOUN
admet-2766	111	15	,	,	PUNCT
admet-2766	111	16	which	which	PRON
admet-2766	111	17	applies	apply	VERB
admet-2766	111	18	a	a	DET
admet-2766	111	19	constant	constant	ADJ
admet-2766	111	20	potential	potential	NOUN
admet-2766	111	21	for	for	ADP
admet-2766	111	22	a	a	DET
admet-2766	111	23	set	set	ADJ
admet-2766	111	24	duration	duration	NOUN
admet-2766	111	25	while	while	SCONJ
admet-2766	111	26	measuring	measure	VERB
admet-2766	111	27	the	the	DET
admet-2766	111	28	associated	associated	ADJ
admet-2766	111	29	current	current	ADJ
admet-2766	111	30	response	response	NOUN
admet-2766	112	1	[	[	X
admet-2766	112	2	40	40	NUM
admet-2766	112	3	]	]	PUNCT
admet-2766	112	4	.	.	PUNCT
admet-2766	113	1	during	during	ADP
admet-2766	113	2	this	this	DET
admet-2766	113	3	process	process	NOUN
admet-2766	113	4	,	,	PUNCT
admet-2766	113	5	tetrachloroaurate	tetrachloroaurate	NOUN
admet-2766	113	6	ions	ion	NOUN
admet-2766	113	7	(	(	PUNCT
admet-2766	113	8	aucl4⁻	aucl4⁻	NOUN
admet-2766	113	9	)	)	PUNCT
admet-2766	113	10	undergo	undergo	VERB
admet-2766	113	11	electrochemical	electrochemical	ADJ
admet-2766	113	12	reduction	reduction	NOUN
admet-2766	113	13	to	to	ADP
admet-2766	113	14	solid	solid	ADJ
admet-2766	113	15	gold	gold	NOUN
admet-2766	113	16	(	(	PUNCT
admet-2766	113	17	au0	au0	PROPN
admet-2766	113	18	)	)	PUNCT
admet-2766	113	19	,	,	PUNCT
admet-2766	113	20	which	which	PRON
admet-2766	113	21	deposits	deposit	VERB
admet-2766	113	22	onto	onto	ADP
admet-2766	113	23	the	the	DET
admet-2766	113	24	electrode	electrode	NOUN
admet-2766	113	25	surface	surface	NOUN
admet-2766	113	26	.	.	PUNCT
admet-2766	114	1	a	a	DET
admet-2766	114	2	potential	potential	NOUN
admet-2766	114	3	of	of	ADP
admet-2766	114	4	-0.1	-0.1	PROPN
admet-2766	114	5	v	v	NOUN
admet-2766	114	6	was	be	AUX
admet-2766	114	7	applied	apply	VERB
admet-2766	114	8	to	to	PART
admet-2766	114	9	facilitate	facilitate	VERB
admet-2766	114	10	the	the	DET
admet-2766	114	11	formation	formation	NOUN
admet-2766	114	12	of	of	ADP
admet-2766	114	13	aunps	aunps	PROPN
admet-2766	114	14	,	,	PUNCT
admet-2766	114	15	selected	select	VERB
admet-2766	114	16	based	base	VERB
admet-2766	114	17	on	on	ADP
admet-2766	114	18	the	the	DET
admet-2766	114	19	reduction	reduction	NOUN
admet-2766	114	20	peak	peak	NOUN
admet-2766	114	21	of	of	ADP
admet-2766	114	22	haucl4	haucl4	NOUN
admet-2766	114	23	to	to	PART
admet-2766	114	24	au0	au0	VERB
admet-2766	115	1	[	[	X
admet-2766	115	2	41	41	NUM
admet-2766	115	3	]	]	PUNCT
admet-2766	115	4	.	.	PUNCT
admet-2766	116	1	potential	potential	ADJ
admet-2766	116	2	,	,	PUNCT
admet-2766	116	3	v	v	NOUN
admet-2766	116	4	vs.	vs.	X
admet-2766	116	5	ag	ag	PROPN
admet-2766	116	6	potential	potential	NOUN
admet-2766	116	7	,	,	PUNCT
admet-2766	116	8	v	v	NOUN
admet-2766	116	9	vs.	vs.	X
admet-2766	116	10	ag	ag	PROPN
admet-2766	116	11	figure	figure	NOUN
admet-2766	116	12	3	3	NUM
admet-2766	116	13	.	.	PUNCT
admet-2766	117	1	(	(	PUNCT
admet-2766	117	2	a	a	X
admet-2766	117	3	)	)	PUNCT
admet-2766	117	4	cyclic	cyclic	ADJ
admet-2766	117	5	voltammogram	voltammogram	NOUN
admet-2766	117	6	(	(	PUNCT
admet-2766	117	7	b	b	NOUN
admet-2766	117	8	)	)	PUNCT
admet-2766	117	9	differential	differential	ADJ
admet-2766	117	10	pulse	pulse	NOUN
admet-2766	117	11	voltammogram	voltammogram	NOUN
admet-2766	117	12	,	,	PUNCT
admet-2766	117	13	of	of	ADP
admet-2766	117	14	spce	spce	PROPN
admet-2766	117	15	bare	bare	PROPN
admet-2766	117	16	and	and	CCONJ
admet-2766	117	17	spce	spce	PROPN
admet-2766	117	18	/	/	SYM
admet-2766	117	19	aunps	aunps	PROPN
admet-2766	117	20	using	use	VERB
admet-2766	117	21	a	a	DET
admet-2766	117	22	redox	redox	ADJ
admet-2766	117	23	system	system	NOUN
admet-2766	117	24	of	of	ADP
admet-2766	117	25	10	10	NUM
admet-2766	117	26	mm	mm	NOUN
admet-2766	117	27	k4[fe(cn)6	k4[fe(cn)6	NOUN
admet-2766	117	28	]	]	PUNCT
admet-2766	117	29	in	in	ADP
admet-2766	117	30	a	a	DET
admet-2766	117	31	100	100	NUM
admet-2766	117	32	mm	mm	NOUN
admet-2766	117	33	kcl	kcl	PROPN
admet-2766	117	34	solution	solution	NOUN
admet-2766	117	35	the	the	DET
admet-2766	117	36	electrochemical	electrochemical	ADJ
admet-2766	117	37	performance	performance	NOUN
admet-2766	117	38	of	of	ADP
admet-2766	117	39	the	the	DET
admet-2766	117	40	spce	spce	NOUN
admet-2766	117	41	modified	modify	VERB
admet-2766	117	42	aunps	aunps	PROPN
admet-2766	117	43	was	be	AUX
admet-2766	117	44	evaluated	evaluate	VERB
admet-2766	117	45	using	use	VERB
admet-2766	117	46	cv	cv	PROPN
admet-2766	117	47	and	and	CCONJ
admet-2766	117	48	dpv	dpv	PROPN
admet-2766	117	49	in	in	ADP
admet-2766	117	50	the	the	DET
admet-2766	117	51	presence	presence	NOUN
admet-2766	117	52	of	of	ADP
admet-2766	117	53	the	the	DET
admet-2766	117	54	standard	standard	ADJ
admet-2766	117	55	redox	redox	ADJ
admet-2766	117	56	probe	probe	NOUN
admet-2766	118	1	[	[	X
admet-2766	118	2	fe(cn)6]3-/4-	fe(cn)6]3-/4-	X
admet-2766	118	3	.	.	PUNCT
admet-2766	119	1	the	the	DET
admet-2766	119	2	cv	cv	PROPN
admet-2766	119	3	results	result	NOUN
admet-2766	119	4	showed	show	VERB
admet-2766	119	5	a	a	DET
admet-2766	119	6	decrease	decrease	NOUN
admet-2766	119	7	in	in	ADP
admet-2766	119	8	δe	δe	NOUN
admet-2766	119	9	from	from	ADP
admet-2766	119	10	0.2449	0.2449	NUM
admet-2766	119	11	v	v	NOUN
admet-2766	119	12	for	for	ADP
admet-2766	119	13	the	the	DET
admet-2766	119	14	bare	bare	ADJ
admet-2766	119	15	spce	spce	NOUN
admet-2766	119	16	to	to	ADP
admet-2766	119	17	0.2023	0.2023	NUM
admet-2766	119	18	v	v	NOUN
admet-2766	119	19	for	for	ADP
admet-2766	119	20	spce	spce	PROPN
admet-2766	119	21	/	/	SYM
admet-2766	119	22	au	au	PROPN
admet-2766	119	23	,	,	PUNCT
admet-2766	119	24	indicating	indicate	VERB
admet-2766	119	25	improved	improved	ADJ
admet-2766	119	26	electron	electron	NOUN
admet-2766	119	27	transfer	transfer	NOUN
admet-2766	119	28	kinetics	kinetic	NOUN
admet-2766	119	29	after	after	ADP
admet-2766	119	30	aunps	aunps	PROPN
admet-2766	119	31	modification	modification	NOUN
admet-2766	119	32	(	(	PUNCT
admet-2766	119	33	figure	figure	NOUN
admet-2766	119	34	3a	3a	NUM
admet-2766	119	35	)	)	PUNCT
admet-2766	119	36	.	.	PUNCT
admet-2766	120	1	this	this	DET
admet-2766	120	2	enhancement	enhancement	NOUN
admet-2766	120	3	is	be	AUX
admet-2766	120	4	further	far	ADV
admet-2766	120	5	supported	support	VERB
admet-2766	120	6	by	by	ADP
admet-2766	120	7	dpv	dpv	PROPN
admet-2766	120	8	measurements	measurement	NOUN
admet-2766	120	9	,	,	PUNCT
admet-2766	120	10	which	which	PRON
admet-2766	120	11	revealed	reveal	VERB
admet-2766	120	12	a	a	DET
admet-2766	120	13	1.5	1.5	NUM
admet-2766	120	14	-	-	ADJ
admet-2766	120	15	fold	fold	ADJ
admet-2766	120	16	increase	increase	NOUN
admet-2766	120	17	in	in	ADP
admet-2766	120	18	peak	peak	NOUN
admet-2766	120	19	current	current	NOUN
admet-2766	120	20	compared	compare	VERB
admet-2766	120	21	to	to	ADP
admet-2766	120	22	the	the	DET
admet-2766	120	23	bare	bare	ADJ
admet-2766	120	24	spce	spce	PROPN
admet-2766	120	25	,	,	PUNCT
admet-2766	120	26	confirming	confirm	VERB
admet-2766	120	27	that	that	SCONJ
admet-2766	120	28	aunps	aunps	PROPN
admet-2766	120	29	significantly	significantly	ADV
admet-2766	120	30	facilitate	facilitate	VERB
admet-2766	120	31	electron	electron	NOUN
admet-2766	120	32	transfer	transfer	NOUN
admet-2766	120	33	at	at	ADP
admet-2766	120	34	the	the	DET
admet-2766	120	35	electrode	electrode	NOUN
admet-2766	120	36	surface	surface	NOUN
admet-2766	120	37	(	(	PUNCT
admet-2766	120	38	figure	figure	NOUN
admet-2766	120	39	3b	3b	NUM
admet-2766	120	40	)	)	PUNCT
admet-2766	120	41	.	.	PUNCT
admet-2766	121	1	the	the	DET
admet-2766	121	2	increased	increase	VERB
admet-2766	121	3	peak	peak	NOUN
admet-2766	121	4	current	current	NOUN
admet-2766	121	5	can	can	AUX
admet-2766	121	6	be	be	AUX
admet-2766	121	7	attributed	attribute	VERB
admet-2766	121	8	to	to	ADP
admet-2766	121	9	the	the	DET
admet-2766	121	10	high	high	ADJ
admet-2766	121	11	surface	surface	NOUN
admet-2766	121	12	area	area	NOUN
admet-2766	121	13	and	and	CCONJ
admet-2766	121	14	higher	high	ADJ
admet-2766	121	15	conductivity	conductivity	NOUN
admet-2766	121	16	of	of	ADP
admet-2766	121	17	aunps	aunps	PROPN
admet-2766	121	18	,	,	PUNCT
admet-2766	121	19	which	which	PRON
admet-2766	121	20	provide	provide	VERB
admet-2766	121	21	more	more	ADV
admet-2766	121	22	active	active	ADJ
admet-2766	121	23	sites	site	NOUN
admet-2766	121	24	and	and	CCONJ
admet-2766	121	25	promote	promote	VERB
admet-2766	121	26	faster	fast	ADJ
admet-2766	121	27	electron	electron	NOUN
admet-2766	121	28	exchange	exchange	NOUN
admet-2766	121	29	between	between	ADP
admet-2766	121	30	the	the	DET
admet-2766	121	31	redox	redox	NOUN
admet-2766	121	32	probe	probe	NOUN
admet-2766	121	33	and	and	CCONJ
admet-2766	121	34	the	the	DET
admet-2766	121	35	electrode	electrode	NOUN
admet-2766	121	36	.	.	PUNCT
admet-2766	122	1	overall	overall	ADV
admet-2766	122	2	,	,	PUNCT
admet-2766	122	3	these	these	DET
admet-2766	122	4	results	result	NOUN
admet-2766	122	5	demonstrate	demonstrate	VERB
admet-2766	122	6	that	that	SCONJ
admet-2766	122	7	the	the	DET
admet-2766	122	8	modification	modification	NOUN
admet-2766	122	9	with	with	ADP
admet-2766	122	10	aunps	aunps	PROPN
admet-2766	122	11	effectively	effectively	ADV
admet-2766	122	12	improves	improve	VERB
admet-2766	122	13	the	the	DET
admet-2766	122	14	electrochemical	electrochemical	ADJ
admet-2766	122	15	properties	property	NOUN
admet-2766	122	16	of	of	ADP
admet-2766	122	17	the	the	DET
admet-2766	122	18	electrode	electrode	NOUN
admet-2766	122	19	.	.	PUNCT
admet-2766	123	1	dna	dna	PROPN
admet-2766	123	2	probe	probe	NOUN
admet-2766	123	3	immobilization	immobilization	NOUN
admet-2766	123	4	via	via	ADP
admet-2766	123	5	the	the	DET
admet-2766	123	6	streptavidin	streptavidin	NOUN
admet-2766	123	7	-	-	PUNCT
admet-2766	123	8	biotin	biotin	NOUN
admet-2766	123	9	system	system	NOUN
admet-2766	123	10	the	the	DET
admet-2766	123	11	designed	design	VERB
admet-2766	123	12	dna	dna	PROPN
admet-2766	123	13	probe	probe	NOUN
admet-2766	123	14	incorporates	incorporate	VERB
admet-2766	123	15	a	a	DET
admet-2766	123	16	biotin	biotin	NOUN
admet-2766	123	17	group	group	NOUN
admet-2766	123	18	at	at	ADP
admet-2766	123	19	the	the	DET
admet-2766	123	20	3′	3′	NUM
admet-2766	123	21	end	end	NOUN
admet-2766	123	22	and	and	CCONJ
admet-2766	123	23	a	a	DET
admet-2766	123	24	ferrocene	ferrocene	NOUN
admet-2766	123	25	label	label	NOUN
admet-2766	123	26	at	at	ADP
admet-2766	123	27	the	the	DET
admet-2766	123	28	5′	5′	NUM
admet-2766	123	29	end	end	NOUN
admet-2766	123	30	.	.	PUNCT
admet-2766	124	1	the	the	DET
admet-2766	124	2	biotin	biotin	NOUN
admet-2766	124	3	-	-	PUNCT
admet-2766	124	4	end	end	NOUN
admet-2766	124	5	facilitates	facilitate	VERB
admet-2766	124	6	immobilization	immobilization	NOUN
admet-2766	124	7	onto	onto	ADP
admet-2766	124	8	sensor	sensor	NOUN
admet-2766	124	9	surfaces	surface	NOUN
admet-2766	124	10	via	via	ADP
admet-2766	124	11	the	the	DET
admet-2766	124	12	streptavidin	streptavidin	NOUN
admet-2766	124	13	-	-	PUNCT
admet-2766	124	14	biotin	biotin	NOUN
admet-2766	124	15	interaction	interaction	NOUN
admet-2766	124	16	.	.	PUNCT
admet-2766	125	1	the	the	DET
admet-2766	125	2	streptavidin	streptavidin	PROPN
admet-2766	125	3	-	-	PUNCT
admet-2766	125	4	biotin	biotin	NOUN
admet-2766	125	5	system	system	NOUN
admet-2766	125	6	is	be	AUX
admet-2766	125	7	extensively	extensively	ADV
admet-2766	125	8	employed	employ	VERB
admet-2766	125	9	in	in	ADP
admet-2766	125	10	biosensor	biosensor	NOUN
admet-2766	125	11	applications	application	NOUN
admet-2766	125	12	due	due	ADP
admet-2766	125	13	to	to	ADP
admet-2766	125	14	its	its	PRON
admet-2766	125	15	exceptionally	exceptionally	ADV
admet-2766	125	16	strong	strong	ADJ
admet-2766	125	17	c	c	PROPN
admet-2766	125	18	u	u	NOUN
admet-2766	125	19	rr	rr	PROPN
admet-2766	125	20	en	en	PROPN
admet-2766	125	21	t	t	PROPN
admet-2766	125	22	,	,	PUNCT
admet-2766	125	23			NOUN
admet-2766	125	24	a	a	PRON
admet-2766	125	25	c	c	NOUN
admet-2766	125	26	u	u	NOUN
admet-2766	125	27	rr	rr	PROPN
admet-2766	125	28	en	en	PROPN
admet-2766	125	29	t	t	PROPN
admet-2766	125	30	,	,	PUNCT
admet-2766	125	31			NOUN
admet-2766	125	32	a	a	DET
admet-2766	125	33	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	126	1	d.	d.	PROPN
admet-2766	126	2	a.	a.	PROPN
admet-2766	126	3	wulandari	wulandari	PROPN
admet-2766	126	4	et	et	PROPN
admet-2766	126	5	al	al	PROPN
admet-2766	126	6	.	.	PROPN
admet-2766	126	7	admet	admet	PROPN
admet-2766	126	8	&	&	CCONJ
admet-2766	126	9	dmpk	dmpk	PROPN
admet-2766	126	10	13(3	13(3	NUM
admet-2766	126	11	)	)	PUNCT
admet-2766	126	12	(	(	PUNCT
admet-2766	126	13	2025	2025	NUM
admet-2766	126	14	)	)	PUNCT
admet-2766	126	15	2766	2766	NUM
admet-2766	126	16	8	8	NUM
admet-2766	126	17	and	and	CCONJ
admet-2766	126	18	specific	specific	ADJ
admet-2766	126	19	non	non	ADJ
admet-2766	126	20	-	-	ADJ
admet-2766	126	21	covalent	covalent	ADJ
admet-2766	126	22	interaction	interaction	NOUN
admet-2766	126	23	,	,	PUNCT
admet-2766	126	24	characterized	characterize	VERB
admet-2766	126	25	by	by	ADP
admet-2766	126	26	a	a	DET
admet-2766	126	27	dissociation	dissociation	NOUN
admet-2766	126	28	constant	constant	ADJ
admet-2766	126	29	(	(	PUNCT
admet-2766	126	30	kd	kd	PROPN
admet-2766	126	31	≈	≈	PROPN
admet-2766	126	32	10	10	NUM
admet-2766	126	33	-	-	SYM
admet-2766	126	34	14	14	NUM
admet-2766	126	35	m	m	NOUN
admet-2766	126	36	)	)	PUNCT
admet-2766	126	37	.	.	PUNCT
admet-2766	127	1	this	this	DET
admet-2766	127	2	high	high	ADJ
admet-2766	127	3	-	-	PUNCT
admet-2766	127	4	affinity	affinity	NOUN
admet-2766	127	5	binding	binding	NOUN
admet-2766	127	6	facilitates	facilitate	VERB
admet-2766	127	7	the	the	DET
admet-2766	127	8	stable	stable	ADJ
admet-2766	127	9	and	and	CCONJ
admet-2766	127	10	efficient	efficient	ADJ
admet-2766	127	11	immobilization	immobilization	NOUN
admet-2766	127	12	of	of	ADP
admet-2766	127	13	biotinylated	biotinylated	ADJ
admet-2766	127	14	biomolecules	biomolecule	NOUN
admet-2766	127	15	,	,	PUNCT
admet-2766	127	16	enhancing	enhance	VERB
admet-2766	127	17	the	the	DET
admet-2766	127	18	sensitivity	sensitivity	NOUN
admet-2766	127	19	and	and	CCONJ
admet-2766	127	20	reliability	reliability	NOUN
admet-2766	127	21	of	of	ADP
admet-2766	127	22	biosensors	biosensor	NOUN
admet-2766	127	23	[	[	X
admet-2766	127	24	42	42	NUM
admet-2766	127	25	-	-	SYM
admet-2766	127	26	44	44	NUM
admet-2766	127	27	]	]	PUNCT
admet-2766	127	28	.	.	PUNCT
admet-2766	128	1	the	the	DET
admet-2766	128	2	integration	integration	NOUN
admet-2766	128	3	of	of	ADP
admet-2766	128	4	3	3	NUM
admet-2766	128	5	-	-	PUNCT
admet-2766	128	6	mercaptopropionic	mercaptopropionic	ADJ
admet-2766	128	7	acid	acid	NOUN
admet-2766	128	8	(	(	PUNCT
admet-2766	128	9	mpa	mpa	PROPN
admet-2766	128	10	)	)	PUNCT
admet-2766	128	11	with	with	ADP
admet-2766	128	12	edc	edc	PROPN
admet-2766	128	13	/	/	SYM
admet-2766	128	14	nhs	nhs	PROPN
admet-2766	128	15	chemistry	chemistry	NOUN
admet-2766	128	16	is	be	AUX
admet-2766	128	17	a	a	DET
admet-2766	128	18	prevalent	prevalent	ADJ
admet-2766	128	19	method	method	NOUN
admet-2766	128	20	for	for	ADP
admet-2766	128	21	the	the	DET
admet-2766	128	22	covalent	covalent	ADJ
admet-2766	128	23	immobilization	immobilization	NOUN
admet-2766	128	24	of	of	ADP
admet-2766	128	25	biomolecules	biomolecule	NOUN
admet-2766	128	26	on	on	ADP
admet-2766	128	27	biosensor	biosensor	NOUN
admet-2766	128	28	surfaces	surface	NOUN
admet-2766	128	29	,	,	PUNCT
admet-2766	128	30	particularly	particularly	ADV
admet-2766	128	31	gold	gold	NOUN
admet-2766	128	32	electrodes	electrode	NOUN
admet-2766	128	33	.	.	PUNCT
admet-2766	129	1	mpa	mpa	PROPN
admet-2766	129	2	forms	form	VERB
admet-2766	129	3	a	a	DET
admet-2766	129	4	self	self	NOUN
admet-2766	129	5	-	-	PUNCT
admet-2766	129	6	assembled	assemble	VERB
admet-2766	129	7	monolayer	monolayer	NOUN
admet-2766	129	8	(	(	PUNCT
admet-2766	129	9	sam	sam	PROPN
admet-2766	129	10	)	)	PUNCT
admet-2766	129	11	on	on	ADP
admet-2766	129	12	gold	gold	NOUN
admet-2766	129	13	,	,	PUNCT
admet-2766	129	14	exposing	expose	VERB
admet-2766	129	15	carboxyl	carboxyl	NOUN
admet-2766	129	16	groups	group	NOUN
admet-2766	129	17	that	that	PRON
admet-2766	129	18	can	can	AUX
admet-2766	129	19	be	be	AUX
admet-2766	129	20	activated	activate	VERB
admet-2766	129	21	by	by	ADP
admet-2766	129	22	edc	edc	PROPN
admet-2766	129	23	(	(	PUNCT
admet-2766	129	24	1	1	NUM
admet-2766	129	25	-	-	PUNCT
admet-2766	129	26	ethyl-3-(3	ethyl-3-(3	ADV
admet-2766	129	27	-	-	PUNCT
admet-2766	129	28	dimethylaminopropyl)carbodiimide	dimethylaminopropyl)carbodiimide	NOUN
admet-2766	129	29	)	)	PUNCT
admet-2766	129	30	and	and	CCONJ
admet-2766	129	31	nhs	nhs	PROPN
admet-2766	129	32	(	(	PUNCT
admet-2766	129	33	nhydroxysuccinimide	nhydroxysuccinimide	ADV
admet-2766	129	34	)	)	PUNCT
admet-2766	129	35	to	to	PART
admet-2766	129	36	generate	generate	VERB
admet-2766	129	37	reactive	reactive	ADJ
admet-2766	129	38	esters	ester	NOUN
admet-2766	129	39	.	.	PUNCT
admet-2766	130	1	in	in	ADP
admet-2766	130	2	this	this	DET
admet-2766	130	3	experiment	experiment	NOUN
admet-2766	130	4	,	,	PUNCT
admet-2766	130	5	these	these	DET
admet-2766	130	6	esters	ester	NOUN
admet-2766	130	7	readily	readily	ADV
admet-2766	130	8	react	react	VERB
admet-2766	130	9	with	with	ADP
admet-2766	130	10	primary	primary	ADJ
admet-2766	130	11	amine	amine	ADJ
admet-2766	130	12	groups	group	NOUN
admet-2766	130	13	of	of	ADP
admet-2766	130	14	biomolecules	biomolecule	NOUN
admet-2766	130	15	,	,	PUNCT
admet-2766	130	16	such	such	ADJ
admet-2766	130	17	as	as	ADP
admet-2766	130	18	streptavidin	streptavidin	VERB
admet-2766	130	19	,	,	PUNCT
admet-2766	130	20	forming	form	VERB
admet-2766	130	21	a	a	DET
admet-2766	130	22	stable	stable	ADJ
admet-2766	130	23	amide	amide	NOUN
admet-2766	130	24	bond	bond	NOUN
admet-2766	130	25	that	that	PRON
admet-2766	130	26	attaches	attach	VERB
admet-2766	130	27	the	the	DET
admet-2766	130	28	biomolecules	biomolecule	NOUN
admet-2766	130	29	onto	onto	ADP
admet-2766	130	30	the	the	DET
admet-2766	130	31	sensor	sensor	NOUN
admet-2766	130	32	surface	surface	NOUN
admet-2766	130	33	[	[	X
admet-2766	130	34	45	45	NUM
admet-2766	130	35	]	]	PUNCT
admet-2766	130	36	.	.	PUNCT
admet-2766	131	1	after	after	SCONJ
admet-2766	131	2	the	the	DET
admet-2766	131	3	biotinylated	biotinylated	ADJ
admet-2766	131	4	dna	dna	PROPN
admet-2766	131	5	probe	probe	NOUN
admet-2766	131	6	-	-	PUNCT
admet-2766	131	7	fc	fc	PROPN
admet-2766	131	8	is	be	AUX
admet-2766	131	9	immobilized	immobilize	VERB
admet-2766	131	10	onto	onto	ADP
admet-2766	131	11	the	the	DET
admet-2766	131	12	spce	spce	PROPN
admet-2766	131	13	surface	surface	NOUN
admet-2766	131	14	via	via	ADP
admet-2766	131	15	streptavidin	streptavidin	NOUN
admet-2766	131	16	-	-	PUNCT
admet-2766	131	17	biotin	biotin	NOUN
admet-2766	131	18	binding	binding	NOUN
admet-2766	131	19	,	,	PUNCT
admet-2766	131	20	bsa	bsa	PROPN
admet-2766	131	21	is	be	AUX
admet-2766	131	22	immobilized	immobilize	VERB
admet-2766	131	23	as	as	ADP
admet-2766	131	24	a	a	DET
admet-2766	131	25	blocking	block	VERB
admet-2766	131	26	agent	agent	NOUN
admet-2766	131	27	.	.	PUNCT
admet-2766	132	1	bsa	bsa	PROPN
admet-2766	132	2	effectively	effectively	ADV
admet-2766	132	3	occupies	occupy	VERB
admet-2766	132	4	unbound	unbound	NOUN
admet-2766	132	5	sites	site	NOUN
admet-2766	132	6	on	on	ADP
admet-2766	132	7	the	the	DET
admet-2766	132	8	sensor	sensor	NOUN
admet-2766	132	9	surface	surface	NOUN
admet-2766	132	10	,	,	PUNCT
admet-2766	132	11	thereby	thereby	ADV
admet-2766	132	12	minimizing	minimize	VERB
admet-2766	132	13	nonspecific	nonspecific	ADJ
admet-2766	132	14	adsorption	adsorption	NOUN
admet-2766	132	15	of	of	ADP
admet-2766	132	16	biomolecules	biomolecule	NOUN
admet-2766	132	17	.	.	PUNCT
admet-2766	133	1	this	this	DET
admet-2766	133	2	reduction	reduction	NOUN
admet-2766	133	3	in	in	ADP
admet-2766	133	4	nonspecific	nonspecific	ADJ
admet-2766	133	5	binding	bind	VERB
admet-2766	133	6	decreases	decrease	NOUN
admet-2766	133	7	background	background	NOUN
admet-2766	133	8	noise	noise	NOUN
admet-2766	133	9	and	and	CCONJ
admet-2766	133	10	enhances	enhance	VERB
admet-2766	133	11	the	the	DET
admet-2766	133	12	sensitivity	sensitivity	NOUN
admet-2766	133	13	of	of	ADP
admet-2766	133	14	the	the	DET
admet-2766	133	15	biosensor	biosensor	NOUN
admet-2766	133	16	assay	assay	VERB
admet-2766	133	17	[	[	X
admet-2766	133	18	46	46	NUM
admet-2766	133	19	]	]	PUNCT
admet-2766	133	20	.	.	PUNCT
admet-2766	134	1	potential	potential	ADJ
admet-2766	134	2	,	,	PUNCT
admet-2766	134	3	v	v	NOUN
admet-2766	134	4	vs.	vs.	X
admet-2766	134	5	ag	ag	PROPN
admet-2766	134	6	potential	potential	NOUN
admet-2766	134	7	,	,	PUNCT
admet-2766	134	8	v	v	NOUN
admet-2766	134	9	vs.	vs.	ADP
admet-2766	134	10	ag	ag	PROPN
admet-2766	134	11	figure	figure	NOUN
admet-2766	134	12	4	4	NUM
admet-2766	134	13	.	.	PUNCT
admet-2766	134	14	square	square	PROPN
admet-2766	134	15	wave	wave	PROPN
admet-2766	134	16	voltammogram	voltammogram	NOUN
admet-2766	134	17	characterization	characterization	NOUN
admet-2766	134	18	of	of	ADP
admet-2766	134	19	ferrocene	ferrocene	ADJ
admet-2766	134	20	redox	redox	NOUN
admet-2766	134	21	system	system	NOUN
admet-2766	134	22	(	(	PUNCT
admet-2766	134	23	a	a	X
admet-2766	134	24	)	)	PUNCT
admet-2766	134	25	at	at	ADP
admet-2766	134	26	spce	spce	PROPN
admet-2766	134	27	bare	bare	PROPN
admet-2766	134	28	,	,	PUNCT
admet-2766	134	29	spce	spce	PROPN
admet-2766	134	30	/	/	SYM
admet-2766	134	31	aunps	aunps	PROPN
admet-2766	134	32	,	,	PUNCT
admet-2766	134	33	spce	spce	PROPN
admet-2766	134	34	/	/	SYM
admet-2766	134	35	aunps	aunps	PROPN
admet-2766	134	36	/	/	SYM
admet-2766	134	37	stv	stv	PROPN
admet-2766	134	38	/	/	SYM
admet-2766	134	39	dna	dna	PROPN
admet-2766	134	40	probe	probe	NOUN
admet-2766	134	41	-	-	PUNCT
admet-2766	134	42	fc	fc	PROPN
admet-2766	134	43	(	(	PUNCT
admet-2766	134	44	b	b	NOUN
admet-2766	134	45	)	)	PUNCT
admet-2766	134	46	for	for	ADP
admet-2766	134	47	target	target	NOUN
admet-2766	134	48	recognition	recognition	NOUN
admet-2766	134	49	using	use	VERB
admet-2766	134	50	crispr	crispr	ADJ
admet-2766	134	51	/	/	SYM
admet-2766	134	52	cas9	cas9	NOUN
admet-2766	134	53	system	system	NOUN
admet-2766	134	54	,	,	PUNCT
admet-2766	134	55	in	in	ADP
admet-2766	134	56	1x	1x	PROPN
admet-2766	134	57	pbs	pbs	PROPN
admet-2766	134	58	solution	solution	NOUN
admet-2766	134	59	the	the	DET
admet-2766	134	60	modification	modification	NOUN
admet-2766	134	61	of	of	ADP
admet-2766	134	62	the	the	DET
admet-2766	134	63	dna	dna	PROPN
admet-2766	134	64	probe	probe	NOUN
admet-2766	134	65	on	on	ADP
admet-2766	134	66	the	the	DET
admet-2766	134	67	spce	spce	NOUN
admet-2766	134	68	and	and	CCONJ
admet-2766	134	69	the	the	DET
admet-2766	134	70	application	application	NOUN
admet-2766	134	71	of	of	ADP
admet-2766	134	72	the	the	DET
admet-2766	134	73	crispr	crispr	ADJ
admet-2766	134	74	/	/	SYM
admet-2766	134	75	cas9	cas9	NOUN
admet-2766	134	76	system	system	NOUN
admet-2766	134	77	for	for	ADP
admet-2766	134	78	target	target	NOUN
admet-2766	134	79	dna	dna	PROPN
admet-2766	134	80	mutation	mutation	NOUN
admet-2766	134	81	recognition	recognition	NOUN
admet-2766	134	82	were	be	AUX
admet-2766	134	83	characterized	characterize	VERB
admet-2766	134	84	using	use	VERB
admet-2766	134	85	swv	swv	PROPN
admet-2766	134	86	(	(	PUNCT
admet-2766	134	87	figure	figure	NOUN
admet-2766	134	88	4	4	NUM
admet-2766	134	89	)	)	PUNCT
admet-2766	134	90	.	.	PUNCT
admet-2766	135	1	a	a	DET
admet-2766	135	2	ferrocene	ferrocene	NOUN
admet-2766	135	3	peak	peak	NOUN
admet-2766	135	4	was	be	AUX
admet-2766	135	5	observed	observe	VERB
admet-2766	135	6	on	on	ADP
admet-2766	135	7	spce	spce	PROPN
admet-2766	135	8	/	/	SYM
admet-2766	135	9	aunps	aunps	PROPN
admet-2766	135	10	/	/	SYM
admet-2766	135	11	stv	stv	PROPN
admet-2766	135	12	/	/	SYM
admet-2766	135	13	dna	dna	PROPN
admet-2766	135	14	probe	probe	NOUN
admet-2766	135	15	-	-	PUNCT
admet-2766	135	16	fc	fc	PROPN
admet-2766	135	17	(	(	PUNCT
admet-2766	135	18	figure	figure	NOUN
admet-2766	135	19	4a	4a	NUM
admet-2766	135	20	)	)	PUNCT
admet-2766	135	21	.	.	PUNCT
admet-2766	136	1	ferrocene	ferrocene	NOUN
admet-2766	136	2	is	be	AUX
admet-2766	136	3	an	an	DET
admet-2766	136	4	electroactive	electroactive	ADJ
admet-2766	136	5	molecule	molecule	NOUN
admet-2766	136	6	that	that	PRON
admet-2766	136	7	undergoes	undergo	VERB
admet-2766	136	8	a	a	DET
admet-2766	136	9	reversible	reversible	ADJ
admet-2766	136	10	electron	electron	NOUN
admet-2766	136	11	oxidation	oxidation	NOUN
admet-2766	136	12	to	to	PART
admet-2766	136	13	form	form	VERB
admet-2766	136	14	ferrocenium	ferrocenium	NOUN
admet-2766	136	15	at	at	ADP
admet-2766	136	16	a	a	DET
admet-2766	136	17	potential	potential	NOUN
admet-2766	136	18	of	of	ADP
admet-2766	136	19	approximately	approximately	ADV
admet-2766	136	20	+0.2	+0.2	NOUN
admet-2766	136	21	v	v	NOUN
admet-2766	136	22	,	,	PUNCT
admet-2766	136	23	as	as	SCONJ
admet-2766	136	24	represented	represent	VERB
admet-2766	136	25	by	by	ADP
admet-2766	136	26	the	the	DET
admet-2766	136	27	redox	redox	ADJ
admet-2766	136	28	reaction	reaction	NOUN
admet-2766	136	29	in	in	ADP
admet-2766	136	30	figure	figure	NOUN
admet-2766	136	31	5	5	NUM
admet-2766	136	32	.	.	PUNCT
admet-2766	137	1	this	this	DET
admet-2766	137	2	peak	peak	NOUN
admet-2766	137	3	and	and	CCONJ
admet-2766	137	4	redox	redox	NOUN
admet-2766	137	5	behaviour	behaviour	NOUN
admet-2766	137	6	confirms	confirm	VERB
admet-2766	137	7	the	the	DET
admet-2766	137	8	successful	successful	ADJ
admet-2766	137	9	immobilization	immobilization	NOUN
admet-2766	137	10	of	of	ADP
admet-2766	137	11	the	the	DET
admet-2766	137	12	ferrocene	ferrocene	NOUN
admet-2766	137	13	-	-	PUNCT
admet-2766	137	14	labelled	label	VERB
admet-2766	137	15	dna	dna	NOUN
admet-2766	137	16	probe	probe	NOUN
admet-2766	137	17	on	on	ADP
admet-2766	137	18	the	the	DET
admet-2766	137	19	electrode	electrode	NOUN
admet-2766	137	20	surface	surface	NOUN
admet-2766	137	21	and	and	CCONJ
admet-2766	137	22	its	its	PRON
admet-2766	137	23	electrochemical	electrochemical	ADJ
admet-2766	137	24	activity	activity	NOUN
admet-2766	137	25	.	.	PUNCT
admet-2766	138	1	figure	figure	NOUN
admet-2766	138	2	5	5	NUM
admet-2766	138	3	.	.	PUNCT
admet-2766	138	4	ferrocene	ferrocene	NOUN
admet-2766	138	5	/	/	SYM
admet-2766	138	6	ferrocene+	ferrocene+	VERB
admet-2766	138	7	redox	redox	ADJ
admet-2766	138	8	reaction	reaction	NOUN
admet-2766	138	9	,	,	PUNCT
admet-2766	138	10	created	create	VERB
admet-2766	138	11	by	by	ADP
admet-2766	138	12	the	the	DET
admet-2766	138	13	author	author	NOUN
admet-2766	138	14	based	base	VERB
admet-2766	138	15	on	on	ADP
admet-2766	138	16	information	information	NOUN
admet-2766	138	17	from	from	ADP
admet-2766	138	18	[	[	X
admet-2766	138	19	47	47	NUM
admet-2766	138	20	]	]	PUNCT
admet-2766	138	21	the	the	DET
admet-2766	138	22	hybridization	hybridization	NOUN
admet-2766	138	23	of	of	ADP
admet-2766	138	24	the	the	DET
admet-2766	138	25	complementary	complementary	ADJ
admet-2766	138	26	target	target	NOUN
admet-2766	138	27	dna	dna	NOUN
admet-2766	138	28	with	with	ADP
admet-2766	138	29	the	the	DET
admet-2766	138	30	ferrocene	ferrocene	NOUN
admet-2766	138	31	-	-	PUNCT
admet-2766	138	32	labelled	label	VERB
admet-2766	138	33	probe	probe	NOUN
admet-2766	138	34	dna	dna	NOUN
admet-2766	138	35	on	on	ADP
admet-2766	138	36	the	the	DET
admet-2766	138	37	surface	surface	NOUN
admet-2766	138	38	of	of	ADP
admet-2766	138	39	the	the	DET
admet-2766	138	40	spce	spce	NOUN
admet-2766	138	41	facilitates	facilitate	VERB
admet-2766	138	42	the	the	DET
admet-2766	138	43	formation	formation	NOUN
admet-2766	138	44	of	of	ADP
admet-2766	138	45	double	double	ADJ
admet-2766	138	46	-	-	PUNCT
admet-2766	138	47	stranded	strand	VERB
admet-2766	138	48	dna	dna	NOUN
admet-2766	138	49	(	(	PUNCT
admet-2766	138	50	dsdna	dsdna	NOUN
admet-2766	138	51	)	)	PUNCT
admet-2766	138	52	,	,	PUNCT
admet-2766	138	53	which	which	PRON
admet-2766	138	54	is	be	AUX
admet-2766	138	55	crucial	crucial	ADJ
admet-2766	138	56	for	for	ADP
admet-2766	138	57	recognition	recognition	NOUN
admet-2766	138	58	and	and	CCONJ
admet-2766	138	59	cleavage	cleavage	NOUN
admet-2766	138	60	by	by	ADP
admet-2766	138	61	the	the	DET
admet-2766	138	62	cas9	cas9	NOUN
admet-2766	138	63	/	/	SYM
admet-2766	138	64	grna	grna	NOUN
admet-2766	138	65	complex	complex	NOUN
admet-2766	138	66	.	.	PUNCT
admet-2766	139	1	cas9	cas9	NOUN
admet-2766	139	2	,	,	PUNCT
admet-2766	139	3	guided	guide	VERB
admet-2766	139	4	by	by	ADP
admet-2766	139	5	the	the	DET
admet-2766	139	6	sgrna	sgrna	NOUN
admet-2766	139	7	,	,	PUNCT
admet-2766	139	8	specifically	specifically	ADV
admet-2766	139	9	binds	bind	VERB
admet-2766	139	10	to	to	ADP
admet-2766	139	11	the	the	DET
admet-2766	139	12	protospacer	protospacer	NOUN
admet-2766	139	13	adjacent	adjacent	ADJ
admet-2766	139	14	motif	motif	NOUN
admet-2766	139	15	(	(	PUNCT
admet-2766	139	16	pam	pam	NOUN
admet-2766	139	17	)	)	PUNCT
admet-2766	139	18	sequence	sequence	NOUN
admet-2766	139	19	and	and	CCONJ
admet-2766	139	20	induces	induce	VERB
admet-2766	139	21	local	local	ADJ
admet-2766	139	22	dna	dna	NOUN
admet-2766	139	23	strand	strand	NOUN
admet-2766	139	24	separation	separation	NOUN
admet-2766	139	25	,	,	PUNCT
admet-2766	139	26	enabling	enable	VERB
admet-2766	139	27	the	the	DET
admet-2766	139	28	formation	formation	NOUN
admet-2766	139	29	of	of	ADP
admet-2766	139	30	an	an	DET
admet-2766	139	31	rc	rc	PROPN
admet-2766	139	32	u	u	PROPN
admet-2766	139	33	rr	rr	PROPN
admet-2766	139	34	en	en	PROPN
admet-2766	139	35	t	t	PROPN
admet-2766	139	36	,	,	PUNCT
admet-2766	139	37			NOUN
admet-2766	139	38	a	a	PRON
admet-2766	139	39	c	c	NOUN
admet-2766	139	40	u	u	NOUN
admet-2766	139	41	rr	rr	PROPN
admet-2766	139	42	en	en	PROPN
admet-2766	139	43	t	t	PROPN
admet-2766	139	44	,	,	PUNCT
admet-2766	139	45			NOUN
admet-2766	139	46	a	a	DET
admet-2766	139	47	admet	admet	PROPN
admet-2766	139	48	&	&	CCONJ
admet-2766	139	49	dmpk	dmpk	PROPN
admet-2766	139	50	13(3	13(3	NUM
admet-2766	139	51	)	)	PUNCT
admet-2766	139	52	(	(	PUNCT
admet-2766	139	53	2025	2025	NUM
admet-2766	139	54	)	)	PUNCT
admet-2766	139	55	2766	2766	NUM
admet-2766	139	56	crispr	crispr	ADJ
admet-2766	139	57	/	/	SYM
admet-2766	139	58	cas9	cas9	NOUN
admet-2766	139	59	biosensor	biosensor	NOUN
admet-2766	139	60	for	for	ADP
admet-2766	139	61	the	the	DET
admet-2766	139	62	detection	detection	NOUN
admet-2766	139	63	of	of	ADP
admet-2766	139	64	katg	katg	PROPN
admet-2766	139	65	gene	gene	NOUN
admet-2766	139	66	mutations	mutation	NOUN
admet-2766	139	67	doi	doi	NOUN
admet-2766	139	68	:	:	PUNCT
admet-2766	139	69	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	139	70	9	9	NUM
admet-2766	139	71	loop	loop	NOUN
admet-2766	139	72	structure	structure	NOUN
admet-2766	139	73	necessary	necessary	ADJ
admet-2766	139	74	for	for	ADP
admet-2766	139	75	targeted	target	VERB
admet-2766	139	76	dsdna	dsdna	ADJ
admet-2766	139	77	cleavage	cleavage	NOUN
admet-2766	139	78	[	[	X
admet-2766	139	79	48	48	NUM
admet-2766	139	80	]	]	PUNCT
admet-2766	139	81	.	.	PUNCT
admet-2766	140	1	electrochemical	electrochemical	ADJ
admet-2766	140	2	characterization	characterization	NOUN
admet-2766	140	3	using	use	VERB
admet-2766	140	4	swv	swv	PROPN
admet-2766	140	5	revealed	reveal	VERB
admet-2766	140	6	a	a	DET
admet-2766	140	7	significant	significant	ADJ
admet-2766	140	8	decrease	decrease	NOUN
admet-2766	140	9	in	in	ADP
admet-2766	140	10	the	the	DET
admet-2766	140	11	ferrocene	ferrocene	NOUN
admet-2766	140	12	oxidation	oxidation	NOUN
admet-2766	140	13	current	current	NOUN
admet-2766	140	14	in	in	ADP
admet-2766	140	15	the	the	DET
admet-2766	140	16	presence	presence	NOUN
admet-2766	140	17	of	of	ADP
admet-2766	140	18	the	the	DET
admet-2766	140	19	target	target	NOUN
admet-2766	140	20	dna	dna	NOUN
admet-2766	140	21	compared	compare	VERB
admet-2766	140	22	to	to	ADP
admet-2766	140	23	the	the	DET
admet-2766	140	24	blank	blank	NOUN
admet-2766	140	25	(	(	PUNCT
admet-2766	140	26	without	without	ADP
admet-2766	140	27	target	target	NOUN
admet-2766	140	28	)	)	PUNCT
admet-2766	140	29	,	,	PUNCT
admet-2766	140	30	as	as	SCONJ
admet-2766	140	31	shown	show	VERB
admet-2766	140	32	in	in	ADP
admet-2766	140	33	figure	figure	NOUN
admet-2766	140	34	4b	4b	PROPN
admet-2766	140	35	.	.	PUNCT
admet-2766	141	1	this	this	DET
admet-2766	141	2	reduction	reduction	NOUN
admet-2766	141	3	in	in	ADP
admet-2766	141	4	current	current	ADJ
admet-2766	141	5	indicates	indicate	VERB
admet-2766	141	6	successful	successful	ADJ
admet-2766	141	7	cleavage	cleavage	NOUN
admet-2766	141	8	of	of	ADP
admet-2766	141	9	the	the	DET
admet-2766	141	10	dsdna	dsdna	NOUN
admet-2766	141	11	by	by	ADP
admet-2766	141	12	the	the	DET
admet-2766	141	13	cas9	cas9	NOUN
admet-2766	141	14	/	/	SYM
admet-2766	141	15	grna	grna	NOUN
admet-2766	141	16	complex	complex	NOUN
admet-2766	141	17	,	,	PUNCT
admet-2766	141	18	resulting	result	VERB
admet-2766	141	19	in	in	ADP
admet-2766	141	20	the	the	DET
admet-2766	141	21	release	release	NOUN
admet-2766	141	22	of	of	ADP
admet-2766	141	23	ferrocene	ferrocene	NOUN
admet-2766	141	24	-	-	PUNCT
admet-2766	141	25	labelled	label	VERB
admet-2766	141	26	dna	dna	NOUN
admet-2766	141	27	fragments	fragment	NOUN
admet-2766	141	28	from	from	ADP
admet-2766	141	29	the	the	DET
admet-2766	141	30	electrode	electrode	NOUN
admet-2766	141	31	surface	surface	NOUN
admet-2766	141	32	,	,	PUNCT
admet-2766	141	33	which	which	PRON
admet-2766	141	34	decreases	decrease	VERB
admet-2766	141	35	the	the	DET
admet-2766	141	36	electrochemical	electrochemical	ADJ
admet-2766	141	37	signal	signal	NOUN
admet-2766	141	38	.	.	PUNCT
admet-2766	142	1	electrochemical	electrochemical	ADJ
admet-2766	142	2	performance	performance	NOUN
admet-2766	142	3	of	of	ADP
admet-2766	142	4	the	the	DET
admet-2766	142	5	crispr	crispr	NOUN
admet-2766	142	6	/	/	SYM
admet-2766	142	7	cas9	cas9	NOUN
admet-2766	142	8	-	-	PUNCT
admet-2766	142	9	based	base	VERB
admet-2766	142	10	biosensor	biosensor	NOUN
admet-2766	142	11	in	in	ADP
admet-2766	142	12	this	this	DET
admet-2766	142	13	study	study	NOUN
admet-2766	142	14	,	,	PUNCT
admet-2766	142	15	different	different	ADJ
admet-2766	142	16	concentrations	concentration	NOUN
admet-2766	142	17	of	of	ADP
admet-2766	142	18	mutant	mutant	ADJ
admet-2766	142	19	target	target	NOUN
admet-2766	142	20	dna	dna	NOUN
admet-2766	142	21	(	(	PUNCT
admet-2766	142	22	from	from	ADP
admet-2766	142	23	101	101	NUM
admet-2766	142	24	to	to	PART
admet-2766	142	25	106	106	NUM
admet-2766	142	26	am	am	NOUN
admet-2766	142	27	)	)	PUNCT
admet-2766	142	28	were	be	AUX
admet-2766	142	29	tested	test	VERB
admet-2766	142	30	to	to	PART
admet-2766	142	31	evaluate	evaluate	VERB
admet-2766	142	32	the	the	DET
admet-2766	142	33	response	response	NOUN
admet-2766	142	34	trend	trend	NOUN
admet-2766	142	35	of	of	ADP
admet-2766	142	36	the	the	DET
admet-2766	142	37	crispr	crispr	NOUN
admet-2766	142	38	-	-	PUNCT
admet-2766	142	39	based	base	VERB
admet-2766	142	40	electrochemical	electrochemical	ADJ
admet-2766	142	41	biosensor	biosensor	NOUN
admet-2766	142	42	(	(	PUNCT
admet-2766	142	43	figures	figure	VERB
admet-2766	142	44	6a	6a	NOUN
admet-2766	142	45	and	and	CCONJ
admet-2766	142	46	6b	6b	NUM
admet-2766	142	47	)	)	PUNCT
admet-2766	142	48	.	.	PUNCT
admet-2766	143	1	the	the	DET
admet-2766	143	2	voltammogram	voltammogram	NOUN
admet-2766	143	3	showed	show	VERB
admet-2766	143	4	a	a	DET
admet-2766	143	5	decrease	decrease	NOUN
admet-2766	143	6	in	in	ADP
admet-2766	143	7	ferrocene	ferrocene	NOUN
admet-2766	143	8	signal	signal	NOUN
admet-2766	143	9	as	as	SCONJ
admet-2766	143	10	dna	dna	PROPN
admet-2766	143	11	concentration	concentration	NOUN
admet-2766	143	12	increased	increase	VERB
admet-2766	143	13	,	,	PUNCT
admet-2766	143	14	indicating	indicate	VERB
admet-2766	143	15	more	more	ADJ
admet-2766	143	16	dna	dna	PROPN
admet-2766	143	17	cleavage	cleavage	NOUN
admet-2766	143	18	by	by	ADP
admet-2766	143	19	the	the	DET
admet-2766	143	20	cas9	cas9	NOUN
admet-2766	143	21	enzyme	enzyme	NOUN
admet-2766	143	22	.	.	PUNCT
admet-2766	144	1	the	the	DET
admet-2766	144	2	current	current	ADJ
admet-2766	144	3	difference	difference	NOUN
admet-2766	144	4	(	(	PUNCT
admet-2766	144	5	δi	δi	NOUN
admet-2766	144	6	)	)	PUNCT
admet-2766	144	7	between	between	ADP
admet-2766	144	8	each	each	DET
admet-2766	144	9	sample	sample	NOUN
admet-2766	144	10	and	and	CCONJ
admet-2766	144	11	the	the	DET
admet-2766	144	12	blank	blank	NOUN
admet-2766	144	13	was	be	AUX
admet-2766	144	14	used	use	VERB
admet-2766	144	15	to	to	PART
admet-2766	144	16	construct	construct	VERB
admet-2766	144	17	a	a	DET
admet-2766	144	18	calibration	calibration	NOUN
admet-2766	144	19	curve	curve	NOUN
admet-2766	144	20	,	,	PUNCT
admet-2766	144	21	yielding	yield	VERB
admet-2766	144	22	a	a	DET
admet-2766	144	23	regression	regression	NOUN
admet-2766	144	24	equation	equation	NOUN
admet-2766	144	25	of	of	ADP
admet-2766	144	26	y	y	PROPN
admet-2766	144	27	=	=	PUNCT
admet-2766	144	28	0.0972x	0.0972x	PROPN
admet-2766	145	1	+	+	CCONJ
admet-2766	145	2	0.2116	0.2116	NUM
admet-2766	145	3	with	with	ADP
admet-2766	145	4	a	a	DET
admet-2766	145	5	strong	strong	ADJ
admet-2766	145	6	correlation	correlation	NOUN
admet-2766	145	7	(	(	PUNCT
admet-2766	145	8	r2	r2	NOUN
admet-2766	145	9	=	=	SYM
admet-2766	145	10	0.9812	0.9812	NUM
admet-2766	145	11	)	)	PUNCT
admet-2766	145	12	.	.	PUNCT
admet-2766	146	1	the	the	DET
admet-2766	146	2	detection	detection	NOUN
admet-2766	146	3	limit	limit	NOUN
admet-2766	146	4	was	be	AUX
admet-2766	146	5	calculated	calculate	VERB
admet-2766	146	6	to	to	PART
admet-2766	146	7	be	be	AUX
admet-2766	146	8	7.5530	7.5530	NUM
admet-2766	146	9	am	am	NOUN
admet-2766	146	10	,	,	PUNCT
admet-2766	146	11	with	with	ADP
admet-2766	146	12	a	a	DET
admet-2766	146	13	linear	linear	ADJ
admet-2766	146	14	response	response	NOUN
admet-2766	146	15	range	range	VERB
admet-2766	146	16	from	from	ADP
admet-2766	146	17	101	101	NUM
admet-2766	146	18	to	to	PART
admet-2766	146	19	106	106	NUM
admet-2766	146	20	am	am	NOUN
admet-2766	146	21	.	.	PUNCT
admet-2766	147	1	the	the	DET
admet-2766	147	2	results	result	NOUN
admet-2766	147	3	in	in	ADP
admet-2766	147	4	figure	figure	NOUN
admet-2766	147	5	6a	6a	NOUN
admet-2766	147	6	were	be	AUX
admet-2766	147	7	obtained	obtain	VERB
admet-2766	147	8	using	use	VERB
admet-2766	147	9	different	different	ADJ
admet-2766	147	10	electrodes	electrode	NOUN
admet-2766	147	11	for	for	ADP
admet-2766	147	12	each	each	DET
admet-2766	147	13	concentration	concentration	NOUN
admet-2766	147	14	to	to	PART
admet-2766	147	15	assess	assess	VERB
admet-2766	147	16	inter	inter	ADJ
admet-2766	147	17	-	-	ADJ
admet-2766	147	18	electrode	electrode	ADJ
admet-2766	147	19	reproducibility	reproducibility	NOUN
admet-2766	147	20	.	.	PUNCT
admet-2766	148	1	relative	relative	ADJ
admet-2766	148	2	standard	standard	ADJ
admet-2766	148	3	deviation	deviation	NOUN
admet-2766	148	4	(	(	PUNCT
admet-2766	148	5	rsd	rsd	NOUN
admet-2766	148	6	)	)	PUNCT
admet-2766	148	7	values	value	NOUN
admet-2766	148	8	varied	varied	ADJ
admet-2766	148	9	depending	depend	VERB
admet-2766	148	10	on	on	ADP
admet-2766	148	11	the	the	DET
admet-2766	148	12	concentration	concentration	NOUN
admet-2766	148	13	,	,	PUNCT
admet-2766	148	14	ranging	range	VERB
admet-2766	148	15	from	from	ADP
admet-2766	148	16	a	a	DET
admet-2766	148	17	maximum	maximum	NOUN
admet-2766	148	18	of	of	ADP
admet-2766	148	19	5.27	5.27	NUM
admet-2766	148	20	%	%	NOUN
admet-2766	148	21	at	at	ADP
admet-2766	148	22	101	101	NUM
admet-2766	148	23	am	be	AUX
admet-2766	148	24	to	to	ADP
admet-2766	148	25	a	a	DET
admet-2766	148	26	minimum	minimum	NOUN
admet-2766	148	27	of	of	ADP
admet-2766	148	28	0.05	0.05	NUM
admet-2766	148	29	%	%	NOUN
admet-2766	148	30	at	at	ADP
admet-2766	148	31	106	106	NUM
admet-2766	148	32	am	am	NOUN
admet-2766	148	33	,	,	PUNCT
admet-2766	148	34	indicating	indicate	VERB
admet-2766	148	35	high	high	ADJ
admet-2766	148	36	precision	precision	NOUN
admet-2766	148	37	and	and	CCONJ
admet-2766	148	38	consistent	consistent	ADJ
admet-2766	148	39	sensor	sensor	NOUN
admet-2766	148	40	performance	performance	NOUN
admet-2766	148	41	across	across	ADP
admet-2766	148	42	the	the	DET
admet-2766	148	43	tested	test	VERB
admet-2766	148	44	range	range	NOUN
admet-2766	148	45	.	.	PUNCT
admet-2766	149	1	these	these	DET
admet-2766	149	2	findings	finding	NOUN
admet-2766	149	3	confirm	confirm	VERB
admet-2766	149	4	the	the	DET
admet-2766	149	5	biosensor	biosensor	NOUN
admet-2766	149	6	’s	’s	PART
admet-2766	149	7	capability	capability	NOUN
admet-2766	149	8	to	to	PART
admet-2766	149	9	detect	detect	VERB
admet-2766	149	10	very	very	ADV
admet-2766	149	11	low	low	ADJ
admet-2766	149	12	levels	level	NOUN
admet-2766	149	13	of	of	ADP
admet-2766	149	14	mutated	mutate	VERB
admet-2766	149	15	dna	dna	PROPN
admet-2766	149	16	,	,	PUNCT
admet-2766	149	17	which	which	PRON
admet-2766	149	18	is	be	AUX
admet-2766	149	19	crucial	crucial	ADJ
admet-2766	149	20	for	for	ADP
admet-2766	149	21	the	the	DET
admet-2766	149	22	early	early	ADJ
admet-2766	149	23	detection	detection	NOUN
admet-2766	149	24	of	of	ADP
admet-2766	149	25	drug	drug	NOUN
admet-2766	149	26	-	-	PUNCT
admet-2766	149	27	resistant	resistant	ADJ
admet-2766	149	28	tuberculosis	tuberculosis	NOUN
admet-2766	149	29	.	.	PUNCT
admet-2766	150	1	z	z	X
admet-2766	150	2	’	'	PUNCT
admet-2766	150	3	/	/	SYM
admet-2766	150	4			PROPN
admet-2766	150	5	figure	figure	NOUN
admet-2766	150	6	6	6	NUM
admet-2766	150	7	.	.	PUNCT
admet-2766	151	1	(	(	PUNCT
admet-2766	151	2	a	a	X
admet-2766	151	3	)	)	PUNCT
admet-2766	151	4	square	square	ADJ
admet-2766	151	5	wave	wave	NOUN
admet-2766	151	6	voltammogram	voltammogram	NOUN
admet-2766	151	7	characterization	characterization	NOUN
admet-2766	151	8	of	of	ADP
admet-2766	151	9	ferrocene	ferrocene	ADJ
admet-2766	151	10	redox	redox	NOUN
admet-2766	151	11	system	system	NOUN
admet-2766	151	12	at	at	ADP
admet-2766	151	13	various	various	ADJ
admet-2766	151	14	concentrations	concentration	NOUN
admet-2766	151	15	(	(	PUNCT
admet-2766	151	16	101	101	NUM
admet-2766	151	17	,	,	PUNCT
admet-2766	151	18	102	102	NUM
admet-2766	151	19	,	,	PUNCT
admet-2766	151	20	103	103	NUM
admet-2766	151	21	,	,	PUNCT
admet-2766	151	22	104	104	NUM
admet-2766	151	23	,	,	PUNCT
admet-2766	151	24	105	105	NUM
admet-2766	151	25	,	,	PUNCT
admet-2766	151	26	106	106	NUM
admet-2766	151	27	am	am	NOUN
admet-2766	151	28	)	)	PUNCT
admet-2766	151	29	of	of	ADP
admet-2766	151	30	target	target	VERB
admet-2766	151	31	dna	dna	NOUN
admet-2766	151	32	mutant	mutant	NOUN
admet-2766	151	33	in	in	ADP
admet-2766	151	34	in	in	ADP
admet-2766	151	35	1x	1x	PROPN
admet-2766	151	36	pbs	pbs	PROPN
admet-2766	151	37	solution	solution	NOUN
admet-2766	151	38	.	.	PUNCT
admet-2766	152	1	(	(	PUNCT
admet-2766	152	2	b	b	X
admet-2766	152	3	)	)	PUNCT
admet-2766	152	4	plot	plot	NOUN
admet-2766	152	5	of	of	ADP
admet-2766	152	6	δi	δi	PRON
admet-2766	152	7	vs.	vs.	ADP
admet-2766	152	8	log	log	NOUN
admet-2766	152	9	concentration	concentration	NOUN
admet-2766	152	10	of	of	ADP
admet-2766	152	11	target	target	NOUN
admet-2766	152	12	dna	dna	NOUN
admet-2766	152	13	mutant	mutant	NOUN
admet-2766	152	14	in	in	ADP
admet-2766	152	15	figure	figure	NOUN
admet-2766	152	16	5a	5a	NUM
admet-2766	152	17	.	.	PUNCT
admet-2766	153	1	the	the	DET
admet-2766	153	2	error	error	NOUN
admet-2766	153	3	bar	bar	NOUN
admet-2766	153	4	represents	represent	VERB
admet-2766	153	5	the	the	DET
admet-2766	153	6	measurement	measurement	NOUN
admet-2766	153	7	precision	precision	NOUN
admet-2766	153	8	with	with	ADP
admet-2766	153	9	n	n	NOUN
admet-2766	153	10	=	=	SYM
admet-2766	153	11	2	2	NUM
admet-2766	153	12	.	.	PUNCT
admet-2766	153	13	(	(	PUNCT
admet-2766	153	14	c	c	X
admet-2766	153	15	)	)	PUNCT
admet-2766	153	16	histogram	histogram	NOUN
admet-2766	153	17	comparing	compare	VERB
admet-2766	153	18	current	current	ADJ
admet-2766	153	19	responses	response	NOUN
admet-2766	153	20	of	of	ADP
admet-2766	153	21	the	the	DET
admet-2766	153	22	crispr	crispr	ADJ
admet-2766	153	23	/	/	SYM
admet-2766	153	24	cas9	cas9	NOUN
admet-2766	153	25	-	-	PUNCT
admet-2766	153	26	based	base	VERB
admet-2766	153	27	biosensor	biosensor	NOUN
admet-2766	153	28	for	for	ADP
admet-2766	153	29	without	without	ADP
admet-2766	153	30	,	,	PUNCT
admet-2766	153	31	wild	wild	ADJ
admet-2766	153	32	-	-	PUNCT
admet-2766	153	33	type	type	NOUN
admet-2766	153	34	,	,	PUNCT
admet-2766	153	35	and	and	CCONJ
admet-2766	153	36	mutant	mutant	ADJ
admet-2766	153	37	dna	dna	PROPN
admet-2766	153	38	target	target	NOUN
admet-2766	153	39	.	.	PUNCT
admet-2766	154	1	(	(	PUNCT
admet-2766	154	2	d	d	X
admet-2766	154	3	)	)	PUNCT
admet-2766	154	4	nyquist	nyquist	NOUN
admet-2766	154	5	plots	plot	NOUN
admet-2766	154	6	of	of	ADP
admet-2766	154	7	electrochemical	electrochemical	ADJ
admet-2766	154	8	impedance	impedance	NOUN
admet-2766	154	9	spectroscopy	spectroscopy	NOUN
admet-2766	154	10	for	for	ADP
admet-2766	154	11	spce	spce	PROPN
admet-2766	154	12	/	/	SYM
admet-2766	154	13	au	au	PROPN
admet-2766	154	14	(	(	PUNCT
admet-2766	154	15	black	black	NOUN
admet-2766	154	16	)	)	PUNCT
admet-2766	154	17	,	,	PUNCT
admet-2766	154	18	wild	wild	ADJ
admet-2766	154	19	-	-	PUNCT
admet-2766	154	20	type	type	NOUN
admet-2766	154	21	(	(	PUNCT
admet-2766	154	22	blue	blue	NOUN
admet-2766	154	23	)	)	PUNCT
admet-2766	154	24	,	,	PUNCT
admet-2766	154	25	and	and	CCONJ
admet-2766	154	26	mutant	mutant	NOUN
admet-2766	154	27	(	(	PUNCT
admet-2766	154	28	red	red	ADJ
admet-2766	154	29	)	)	PUNCT
admet-2766	154	30	dna	dna	PROPN
admet-2766	154	31	target	target	NOUN
admet-2766	154	32	c	c	NOUN
admet-2766	154	33	u	u	NOUN
admet-2766	154	34	rr	rr	PROPN
admet-2766	154	35	en	en	PROPN
admet-2766	154	36	t	t	PROPN
admet-2766	154	37	,	,	PUNCT
admet-2766	154	38			NOUN
admet-2766	154	39	a	a	PRON
admet-2766	154	40	c	c	NOUN
admet-2766	154	41	u	u	NOUN
admet-2766	154	42	rr	rr	PROPN
admet-2766	154	43	en	en	PROPN
admet-2766	154	44	t	t	PROPN
admet-2766	154	45	,	,	PUNCT
admet-2766	154	46			NOUN
admet-2766	154	47	a	a	DET
admet-2766	154	48			NOUN
admet-2766	155	1	i	i	PRON
admet-2766	155	2	/	/	SYM
admet-2766	155	3			NOUN
admet-2766	155	4	a	a	DET
admet-2766	155	5	−	−	PROPN
admet-2766	155	6	z	z	NOUN
admet-2766	155	7	”	"	PUNCT
admet-2766	155	8	/	/	SYM
admet-2766	155	9			PROPN
admet-2766	155	10	potential	potential	NOUN
admet-2766	155	11	,	,	PUNCT
admet-2766	155	12	v	v	NOUN
admet-2766	155	13	vs.	vs.	ADP
admet-2766	155	14	ag	ag	PROPN
admet-2766	155	15	log	log	NOUN
admet-2766	155	16	(	(	PUNCT
admet-2766	155	17	ctarget	ctarget	VERB
admet-2766	155	18	dna	dna	PROPN
admet-2766	155	19	/	/	SYM
admet-2766	155	20	am	be	AUX
admet-2766	155	21	)	)	PUNCT
admet-2766	156	1	−	−	PROPN
admet-2766	156	2	z	z	X
admet-2766	156	3	”	"	PUNCT
admet-2766	156	4	/	/	SYM
admet-2766	156	5			PROPN
admet-2766	156	6	z	z	NOUN
admet-2766	156	7	’	'	PUNCT
admet-2766	156	8	/	/	SYM
admet-2766	156	9			PROPN
admet-2766	156	10	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	156	11	d.	d.	PROPN
admet-2766	156	12	a.	a.	PROPN
admet-2766	156	13	wulandari	wulandari	PROPN
admet-2766	156	14	et	et	PROPN
admet-2766	156	15	al	al	PROPN
admet-2766	156	16	.	.	PROPN
admet-2766	156	17	admet	admet	PROPN
admet-2766	156	18	&	&	CCONJ
admet-2766	156	19	dmpk	dmpk	PROPN
admet-2766	156	20	13(3	13(3	NUM
admet-2766	156	21	)	)	PUNCT
admet-2766	156	22	(	(	PUNCT
admet-2766	156	23	2025	2025	NUM
admet-2766	156	24	)	)	PUNCT
admet-2766	156	25	2766	2766	NUM
admet-2766	156	26	10	10	NUM
admet-2766	156	27	furthermore	furthermore	ADV
admet-2766	156	28	,	,	PUNCT
admet-2766	156	29	the	the	DET
admet-2766	156	30	crispr	crispr	NOUN
admet-2766	156	31	/	/	SYM
admet-2766	156	32	cas9	cas9	NOUN
admet-2766	156	33	-	-	PUNCT
admet-2766	156	34	based	base	VERB
admet-2766	156	35	electrochemical	electrochemical	ADJ
admet-2766	156	36	biosensor	biosensor	NOUN
admet-2766	156	37	developed	develop	VERB
admet-2766	156	38	in	in	ADP
admet-2766	156	39	this	this	DET
admet-2766	156	40	study	study	NOUN
admet-2766	156	41	was	be	AUX
admet-2766	156	42	tested	test	VERB
admet-2766	156	43	towards	towards	ADP
admet-2766	156	44	non	non	ADJ
admet-2766	156	45	-	-	ADJ
admet-2766	156	46	mutated	mutated	ADJ
admet-2766	156	47	,	,	PUNCT
admet-2766	156	48	wild	wild	ADJ
admet-2766	156	49	-	-	PUNCT
admet-2766	156	50	type	type	NOUN
admet-2766	156	51	tb	tb	ADP
admet-2766	156	52	dna	dna	NOUN
admet-2766	156	53	targets	target	NOUN
admet-2766	156	54	,	,	PUNCT
admet-2766	156	55	which	which	PRON
admet-2766	156	56	contained	contain	VERB
admet-2766	156	57	a	a	DET
admet-2766	156	58	single	single	ADJ
admet-2766	156	59	mismatch	mismatch	NOUN
admet-2766	156	60	at	at	ADP
admet-2766	156	61	position	position	NOUN
admet-2766	156	62	8	8	NUM
admet-2766	156	63	from	from	ADP
admet-2766	156	64	the	the	DET
admet-2766	156	65	pam	pam	NOUN
admet-2766	156	66	site	site	NOUN
admet-2766	156	67	(	(	PUNCT
admet-2766	156	68	figure	figure	NOUN
admet-2766	156	69	6c	6c	PROPN
admet-2766	156	70	)	)	PUNCT
admet-2766	156	71	.	.	PUNCT
admet-2766	157	1	the	the	DET
admet-2766	157	2	mutant	mutant	ADJ
admet-2766	157	3	target	target	NOUN
admet-2766	157	4	(	(	PUNCT
admet-2766	157	5	fully	fully	ADV
admet-2766	157	6	complementary	complementary	ADJ
admet-2766	157	7	to	to	ADP
admet-2766	157	8	the	the	DET
admet-2766	157	9	grna	grna	NOUN
admet-2766	157	10	)	)	PUNCT
admet-2766	157	11	was	be	AUX
admet-2766	157	12	cleaved	cleave	VERB
admet-2766	157	13	by	by	ADP
admet-2766	157	14	cas9	cas9	NOUN
admet-2766	157	15	,	,	PUNCT
admet-2766	157	16	resulting	result	VERB
admet-2766	157	17	in	in	ADP
admet-2766	157	18	a	a	DET
admet-2766	157	19	decreased	decrease	VERB
admet-2766	157	20	ferrocene	ferrocene	NOUN
admet-2766	157	21	current	current	NOUN
admet-2766	157	22	due	due	ADP
admet-2766	157	23	to	to	ADP
admet-2766	157	24	the	the	DET
admet-2766	157	25	disruption	disruption	NOUN
admet-2766	157	26	of	of	ADP
admet-2766	157	27	probe	probe	NOUN
admet-2766	157	28	conformation	conformation	NOUN
admet-2766	157	29	and	and	CCONJ
admet-2766	157	30	electron	electron	NOUN
admet-2766	157	31	transfer	transfer	NOUN
admet-2766	157	32	.	.	PUNCT
admet-2766	158	1	however	however	ADV
admet-2766	158	2	,	,	PUNCT
admet-2766	158	3	the	the	DET
admet-2766	158	4	wild	wild	ADJ
admet-2766	158	5	-	-	PUNCT
admet-2766	158	6	type	type	NOUN
admet-2766	158	7	target	target	NOUN
admet-2766	158	8	shows	show	VERB
admet-2766	158	9	a	a	DET
admet-2766	158	10	complete	complete	ADJ
admet-2766	158	11	loss	loss	NOUN
admet-2766	158	12	of	of	ADP
admet-2766	158	13	ferrocene	ferrocene	NOUN
admet-2766	158	14	current	current	NOUN
admet-2766	158	15	.	.	PUNCT
admet-2766	159	1	this	this	DET
admet-2766	159	2	phenomenon	phenomenon	NOUN
admet-2766	159	3	is	be	AUX
admet-2766	159	4	likely	likely	ADJ
admet-2766	159	5	due	due	ADP
admet-2766	159	6	to	to	ADP
admet-2766	159	7	the	the	DET
admet-2766	159	8	fact	fact	NOUN
admet-2766	159	9	that	that	SCONJ
admet-2766	159	10	cas9	cas9	NOUN
admet-2766	159	11	can	can	AUX
admet-2766	159	12	still	still	ADV
admet-2766	159	13	bind	bind	VERB
admet-2766	159	14	stably	stably	ADV
admet-2766	159	15	to	to	ADP
admet-2766	159	16	dna	dna	PROPN
admet-2766	159	17	targets	target	NOUN
admet-2766	159	18	containing	contain	VERB
admet-2766	159	19	single	single	ADJ
admet-2766	159	20	mismatches	mismatch	NOUN
admet-2766	159	21	in	in	ADP
admet-2766	159	22	the	the	DET
admet-2766	159	23	seed	seed	NOUN
admet-2766	159	24	region	region	NOUN
admet-2766	159	25	(	(	PUNCT
admet-2766	159	26	positions	position	NOUN
admet-2766	159	27	1	1	NUM
admet-2766	159	28	-	-	SYM
admet-2766	159	29	8	8	NUM
admet-2766	159	30	from	from	ADP
admet-2766	159	31	the	the	DET
admet-2766	159	32	pam	pam	NOUN
admet-2766	159	33	site	site	PROPN
admet-2766	159	34	)	)	PUNCT
admet-2766	159	35	,	,	PUNCT
admet-2766	159	36	without	without	ADP
admet-2766	159	37	inducing	induce	VERB
admet-2766	159	38	cleavage	cleavage	NOUN
admet-2766	159	39	.	.	PUNCT
admet-2766	160	1	a	a	DET
admet-2766	160	2	previous	previous	ADJ
admet-2766	160	3	study	study	NOUN
admet-2766	160	4	utilized	utilize	VERB
admet-2766	160	5	förster	förster	NOUN
admet-2766	160	6	resonance	resonance	NOUN
admet-2766	160	7	energy	energy	NOUN
admet-2766	160	8	transfer	transfer	NOUN
admet-2766	160	9	(	(	PUNCT
admet-2766	160	10	fret	fret	NOUN
admet-2766	160	11	)	)	PUNCT
admet-2766	160	12	to	to	PART
admet-2766	160	13	show	show	VERB
admet-2766	160	14	that	that	SCONJ
admet-2766	160	15	such	such	ADJ
admet-2766	160	16	mismatches	mismatch	NOUN
admet-2766	160	17	prevent	prevent	VERB
admet-2766	160	18	the	the	DET
admet-2766	160	19	hnh	hnh	NOUN
admet-2766	160	20	nuclease	nuclease	NOUN
admet-2766	160	21	domain	domain	NOUN
admet-2766	160	22	from	from	ADP
admet-2766	160	23	adopting	adopt	VERB
admet-2766	160	24	the	the	DET
admet-2766	160	25	active	active	ADJ
admet-2766	160	26	conformation	conformation	NOUN
admet-2766	160	27	necessary	necessary	ADJ
admet-2766	160	28	for	for	ADP
admet-2766	160	29	dna	dna	PROPN
admet-2766	160	30	cleavage	cleavage	NOUN
admet-2766	160	31	,	,	PUNCT
admet-2766	160	32	yet	yet	CCONJ
admet-2766	160	33	the	the	DET
admet-2766	160	34	cas9	cas9	NOUN
admet-2766	160	35	/	/	SYM
admet-2766	160	36	grna	grna	NOUN
admet-2766	160	37	complex	complex	NOUN
admet-2766	160	38	remains	remain	VERB
admet-2766	160	39	bound	bind	VERB
admet-2766	160	40	to	to	ADP
admet-2766	160	41	the	the	DET
admet-2766	160	42	dna	dna	PROPN
admet-2766	161	1	[	[	X
admet-2766	161	2	49,50	49,50	X
admet-2766	161	3	]	]	X
admet-2766	161	4	.	.	PUNCT
admet-2766	162	1	this	this	DET
admet-2766	162	2	persistent	persistent	ADJ
admet-2766	162	3	binding	bind	VERB
admet-2766	162	4	forms	form	NOUN
admet-2766	162	5	a	a	DET
admet-2766	162	6	substantial	substantial	ADJ
admet-2766	162	7	complex	complex	NOUN
admet-2766	162	8	on	on	ADP
admet-2766	162	9	the	the	DET
admet-2766	162	10	electrode	electrode	NOUN
admet-2766	162	11	surface	surface	NOUN
admet-2766	162	12	,	,	PUNCT
admet-2766	162	13	potentially	potentially	ADV
admet-2766	162	14	blocking	block	VERB
admet-2766	162	15	the	the	DET
admet-2766	162	16	ferrocene	ferrocene	NOUN
admet-2766	162	17	oxidation	oxidation	NOUN
admet-2766	162	18	completely	completely	ADV
admet-2766	162	19	,	,	PUNCT
admet-2766	162	20	obstructing	obstruct	VERB
admet-2766	162	21	electron	electron	NOUN
admet-2766	162	22	transfer	transfer	NOUN
admet-2766	162	23	from	from	ADP
admet-2766	162	24	the	the	DET
admet-2766	162	25	ferrocene	ferrocene	NOUN
admet-2766	162	26	label	label	NOUN
admet-2766	162	27	to	to	ADP
admet-2766	162	28	the	the	DET
admet-2766	162	29	electrode	electrode	NOUN
admet-2766	162	30	,	,	PUNCT
admet-2766	162	31	resulting	result	VERB
admet-2766	162	32	in	in	ADP
admet-2766	162	33	the	the	DET
admet-2766	162	34	observed	observe	VERB
admet-2766	162	35	loss	loss	NOUN
admet-2766	162	36	of	of	ADP
admet-2766	162	37	redox	redox	ADJ
admet-2766	162	38	current	current	NOUN
admet-2766	162	39	.	.	PUNCT
admet-2766	163	1	although	although	SCONJ
admet-2766	163	2	cleavage	cleavage	NOUN
admet-2766	163	3	is	be	AUX
admet-2766	163	4	inhibited	inhibit	VERB
admet-2766	163	5	,	,	PUNCT
admet-2766	163	6	the	the	DET
admet-2766	163	7	cas9	cas9	NOUN
admet-2766	163	8	/	/	SYM
admet-2766	163	9	grna	grna	NOUN
admet-2766	163	10	/	/	SYM
admet-2766	163	11	dna	dna	PROPN
admet-2766	163	12	complex	complex	NOUN
admet-2766	163	13	remains	remain	VERB
admet-2766	163	14	intact	intact	ADJ
admet-2766	163	15	.	.	PUNCT
admet-2766	164	1	this	this	DET
admet-2766	164	2	large	large	ADJ
admet-2766	164	3	complex	complex	NOUN
admet-2766	164	4	(	(	PUNCT
admet-2766	164	5	160	160	X
admet-2766	164	6	kda	kda	PROPN
admet-2766	164	7	)	)	PUNCT
admet-2766	164	8	,	,	PUNCT
admet-2766	164	9	when	when	SCONJ
admet-2766	164	10	formed	form	VERB
admet-2766	164	11	on	on	ADP
admet-2766	164	12	the	the	DET
admet-2766	164	13	sensor	sensor	NOUN
admet-2766	164	14	surface	surface	NOUN
admet-2766	164	15	,	,	PUNCT
admet-2766	164	16	likely	likely	ADV
admet-2766	164	17	introduces	introduce	VERB
admet-2766	164	18	significant	significant	ADJ
admet-2766	164	19	steric	steric	ADJ
admet-2766	164	20	hindrance	hindrance	NOUN
admet-2766	164	21	that	that	PRON
admet-2766	164	22	physically	physically	ADV
admet-2766	164	23	blocks	block	VERB
admet-2766	164	24	electron	electron	NOUN
admet-2766	164	25	transfer	transfer	NOUN
admet-2766	164	26	between	between	ADP
admet-2766	164	27	the	the	DET
admet-2766	164	28	ferrocene	ferrocene	NOUN
admet-2766	164	29	moiety	moiety	NOUN
admet-2766	164	30	and	and	CCONJ
admet-2766	164	31	the	the	DET
admet-2766	164	32	electrode	electrode	NOUN
admet-2766	164	33	.	.	PUNCT
admet-2766	165	1	to	to	PART
admet-2766	165	2	further	far	ADV
admet-2766	165	3	investigate	investigate	VERB
admet-2766	165	4	this	this	DET
admet-2766	165	5	phenomenon	phenomenon	NOUN
admet-2766	165	6	,	,	PUNCT
admet-2766	165	7	electrochemical	electrochemical	ADJ
admet-2766	165	8	impedance	impedance	NOUN
admet-2766	165	9	spectroscopy	spectroscopy	NOUN
admet-2766	165	10	(	(	PUNCT
admet-2766	165	11	eis	eis	NOUN
admet-2766	165	12	)	)	PUNCT
admet-2766	165	13	was	be	AUX
admet-2766	165	14	employed	employ	VERB
admet-2766	165	15	to	to	PART
admet-2766	165	16	characterize	characterize	VERB
admet-2766	165	17	changes	change	NOUN
admet-2766	165	18	in	in	ADP
admet-2766	165	19	interfacial	interfacial	ADJ
admet-2766	165	20	charge	charge	NOUN
admet-2766	165	21	transfer	transfer	NOUN
admet-2766	165	22	resistance	resistance	NOUN
admet-2766	165	23	(	(	PUNCT
admet-2766	165	24	rct	rct	PROPN
admet-2766	165	25	)	)	PUNCT
admet-2766	165	26	at	at	ADP
admet-2766	165	27	the	the	DET
admet-2766	165	28	modified	modify	VERB
admet-2766	165	29	electrode	electrode	NOUN
admet-2766	165	30	surface	surface	NOUN
admet-2766	165	31	(	(	PUNCT
admet-2766	165	32	figure	figure	NOUN
admet-2766	165	33	6d	6d	NUM
admet-2766	165	34	)	)	PUNCT
admet-2766	165	35	.	.	PUNCT
admet-2766	166	1	the	the	DET
admet-2766	166	2	results	result	NOUN
admet-2766	166	3	revealed	reveal	VERB
admet-2766	166	4	a	a	DET
admet-2766	166	5	significantly	significantly	ADV
admet-2766	166	6	higher	high	ADJ
admet-2766	166	7	rct	rct	PROPN
admet-2766	166	8	value	value	NOUN
admet-2766	166	9	(	(	PUNCT
admet-2766	166	10	355.1	355.1	NUM
admet-2766	166	11			NUM
admet-2766	166	12	)	)	PUNCT
admet-2766	166	13	in	in	ADP
admet-2766	166	14	the	the	DET
admet-2766	166	15	wild	wild	ADJ
admet-2766	166	16	-	-	PUNCT
admet-2766	166	17	type	type	NOUN
admet-2766	166	18	target	target	NOUN
admet-2766	166	19	compared	compare	VERB
admet-2766	166	20	to	to	ADP
admet-2766	166	21	the	the	DET
admet-2766	166	22	mutant	mutant	ADJ
admet-2766	166	23	target	target	NOUN
admet-2766	166	24	.	.	PUNCT
admet-2766	167	1	this	this	DET
admet-2766	167	2	increase	increase	NOUN
admet-2766	167	3	in	in	ADP
admet-2766	167	4	rct	rct	PROPN
admet-2766	167	5	confirms	confirm	VERB
admet-2766	167	6	that	that	SCONJ
admet-2766	167	7	the	the	DET
admet-2766	167	8	surface	surface	NOUN
admet-2766	167	9	becomes	become	VERB
admet-2766	167	10	more	more	ADV
admet-2766	167	11	resistive	resistive	ADJ
admet-2766	167	12	upon	upon	SCONJ
admet-2766	167	13	wild	wild	ADJ
admet-2766	167	14	-	-	PUNCT
admet-2766	167	15	type	type	NOUN
admet-2766	167	16	dna	dna	NOUN
admet-2766	167	17	binding	bind	VERB
admet-2766	167	18	,	,	PUNCT
admet-2766	167	19	consistent	consistent	ADJ
admet-2766	167	20	with	with	ADP
admet-2766	167	21	the	the	DET
admet-2766	167	22	formation	formation	NOUN
admet-2766	167	23	of	of	ADP
admet-2766	167	24	a	a	DET
admet-2766	167	25	large	large	ADJ
admet-2766	167	26	,	,	PUNCT
admet-2766	167	27	non	non	ADJ
admet-2766	167	28	-	-	ADJ
admet-2766	167	29	cleaved	cleaved	ADJ
admet-2766	167	30	cas9	cas9	NOUN
admet-2766	167	31	/	/	SYM
admet-2766	167	32	grna	grna	NOUN
admet-2766	167	33	/	/	SYM
admet-2766	167	34	dna	dna	NOUN
admet-2766	167	35	complex	complex	NOUN
admet-2766	167	36	that	that	SCONJ
admet-2766	167	37	physically	physically	ADV
admet-2766	167	38	blocks	block	VERB
admet-2766	167	39	access	access	NOUN
admet-2766	167	40	of	of	ADP
admet-2766	167	41	the	the	DET
admet-2766	167	42	ferrocene	ferrocene	NOUN
admet-2766	167	43	moiety	moiety	NOUN
admet-2766	167	44	to	to	ADP
admet-2766	167	45	the	the	DET
admet-2766	167	46	electrode	electrode	NOUN
admet-2766	167	47	surface	surface	NOUN
admet-2766	167	48	.	.	PUNCT
admet-2766	168	1	in	in	ADP
admet-2766	168	2	contrast	contrast	NOUN
admet-2766	168	3	,	,	PUNCT
admet-2766	168	4	the	the	DET
admet-2766	168	5	mutant	mutant	ADJ
admet-2766	168	6	target	target	NOUN
admet-2766	168	7	,	,	PUNCT
admet-2766	168	8	which	which	PRON
admet-2766	168	9	undergoes	undergo	VERB
admet-2766	168	10	cleavage	cleavage	NOUN
admet-2766	168	11	,	,	PUNCT
admet-2766	168	12	showed	show	VERB
admet-2766	168	13	lower	low	ADJ
admet-2766	168	14	rct	rct	NOUN
admet-2766	168	15	values	value	NOUN
admet-2766	168	16	(	(	PUNCT
admet-2766	168	17	123.7	123.7	NUM
admet-2766	168	18	ω	ω	NOUN
admet-2766	168	19	)	)	PUNCT
admet-2766	168	20	due	due	ADP
admet-2766	168	21	to	to	ADP
admet-2766	168	22	the	the	DET
admet-2766	168	23	release	release	NOUN
admet-2766	168	24	of	of	ADP
admet-2766	168	25	the	the	DET
admet-2766	168	26	ferrocene	ferrocene	NOUN
admet-2766	168	27	-	-	PUNCT
admet-2766	168	28	labelled	label	VERB
admet-2766	168	29	dna	dna	NOUN
admet-2766	168	30	fragment	fragment	NOUN
admet-2766	168	31	,	,	PUNCT
admet-2766	168	32	which	which	PRON
admet-2766	168	33	restores	restore	VERB
admet-2766	168	34	electron	electron	NOUN
admet-2766	168	35	transfer	transfer	NOUN
admet-2766	168	36	for	for	ADP
admet-2766	168	37	the	the	DET
admet-2766	168	38	[	[	X
admet-2766	168	39	fe(cn)6]3-/4and	fe(cn)6]3-/4and	X
admet-2766	168	40	allows	allow	VERB
admet-2766	168	41	partial	partial	ADJ
admet-2766	168	42	redox	redox	NOUN
admet-2766	168	43	current	current	NOUN
admet-2766	168	44	to	to	PART
admet-2766	168	45	be	be	AUX
admet-2766	168	46	detected	detect	VERB
admet-2766	168	47	.	.	PUNCT
admet-2766	169	1	this	this	DET
admet-2766	169	2	result	result	NOUN
admet-2766	169	3	confirms	confirm	VERB
admet-2766	169	4	that	that	SCONJ
admet-2766	169	5	ferrocene	ferrocene	NOUN
admet-2766	169	6	signal	signal	NOUN
admet-2766	169	7	attenuation	attenuation	NOUN
admet-2766	169	8	in	in	ADP
admet-2766	169	9	the	the	DET
admet-2766	169	10	wild	wild	ADJ
admet-2766	169	11	type	type	NOUN
admet-2766	169	12	is	be	AUX
admet-2766	169	13	not	not	PART
admet-2766	169	14	due	due	ADJ
admet-2766	169	15	to	to	ADP
admet-2766	169	16	cleavage	cleavage	NOUN
admet-2766	169	17	,	,	PUNCT
admet-2766	169	18	but	but	CCONJ
admet-2766	169	19	due	due	ADP
admet-2766	169	20	to	to	ADP
admet-2766	169	21	steric	steric	ADJ
admet-2766	169	22	blockade	blockade	NOUN
admet-2766	169	23	by	by	ADP
admet-2766	169	24	the	the	DET
admet-2766	169	25	cas9	cas9	NOUN
admet-2766	169	26	complex	complex	NOUN
admet-2766	169	27	,	,	PUNCT
admet-2766	169	28	which	which	PRON
admet-2766	169	29	remains	remain	VERB
admet-2766	169	30	bound	bind	VERB
admet-2766	169	31	to	to	ADP
admet-2766	169	32	the	the	DET
admet-2766	169	33	dna	dna	NOUN
admet-2766	169	34	.	.	PUNCT
admet-2766	170	1	this	this	PRON
admet-2766	170	2	is	be	AUX
admet-2766	170	3	further	far	ADV
admet-2766	170	4	supported	support	VERB
admet-2766	170	5	by	by	ADP
admet-2766	170	6	the	the	DET
admet-2766	170	7	observation	observation	NOUN
admet-2766	170	8	that	that	SCONJ
admet-2766	170	9	the	the	DET
admet-2766	170	10	wild	wild	ADJ
admet-2766	170	11	-	-	PUNCT
admet-2766	170	12	type	type	NOUN
admet-2766	170	13	target	target	NOUN
admet-2766	170	14	exhibited	exhibit	VERB
admet-2766	170	15	the	the	DET
admet-2766	170	16	highest	high	ADJ
admet-2766	170	17	rct	rct	PROPN
admet-2766	170	18	,	,	PUNCT
admet-2766	170	19	indicating	indicate	VERB
admet-2766	170	20	the	the	DET
admet-2766	170	21	greatest	great	ADJ
admet-2766	170	22	obstruction	obstruction	NOUN
admet-2766	170	23	to	to	PART
admet-2766	170	24	electron	electron	NOUN
admet-2766	170	25	transfer	transfer	NOUN
admet-2766	170	26	,	,	PUNCT
admet-2766	170	27	whereas	whereas	SCONJ
admet-2766	170	28	the	the	DET
admet-2766	170	29	mutant	mutant	ADJ
admet-2766	170	30	target	target	NOUN
admet-2766	170	31	showed	show	VERB
admet-2766	170	32	a	a	DET
admet-2766	170	33	lower	low	ADJ
admet-2766	170	34	rct	rct	NOUN
admet-2766	170	35	,	,	PUNCT
admet-2766	170	36	suggesting	suggest	VERB
admet-2766	170	37	reduced	reduce	VERB
admet-2766	170	38	hindrance	hindrance	NOUN
admet-2766	170	39	due	due	ADP
admet-2766	170	40	to	to	ADP
admet-2766	170	41	dna	dna	PROPN
admet-2766	170	42	cleavage	cleavage	NOUN
admet-2766	170	43	and	and	CCONJ
admet-2766	170	44	subsequent	subsequent	ADJ
admet-2766	170	45	dissociation	dissociation	NOUN
admet-2766	170	46	of	of	ADP
admet-2766	170	47	the	the	DET
admet-2766	170	48	complex	complex	NOUN
admet-2766	170	49	.	.	PUNCT
admet-2766	171	1	despite	despite	SCONJ
admet-2766	171	2	that	that	PRON
admet-2766	171	3	,	,	PUNCT
admet-2766	171	4	these	these	DET
admet-2766	171	5	findings	finding	NOUN
admet-2766	171	6	indicate	indicate	VERB
admet-2766	171	7	that	that	SCONJ
admet-2766	171	8	crispr	crispr	ADJ
admet-2766	171	9	/	/	SYM
admet-2766	171	10	cas9	cas9	NOUN
admet-2766	171	11	systems	system	NOUN
admet-2766	171	12	can	can	AUX
admet-2766	171	13	discriminate	discriminate	VERB
admet-2766	171	14	single	single	ADJ
admet-2766	171	15	-	-	PUNCT
admet-2766	171	16	base	base	NOUN
admet-2766	171	17	mismatches	mismatch	NOUN
admet-2766	171	18	not	not	PART
admet-2766	171	19	only	only	ADV
admet-2766	171	20	via	via	ADP
admet-2766	171	21	cleavage	cleavage	NOUN
admet-2766	171	22	activity	activity	NOUN
admet-2766	171	23	but	but	CCONJ
admet-2766	171	24	also	also	ADV
admet-2766	171	25	through	through	ADP
admet-2766	171	26	non	non	ADJ
admet-2766	171	27	-	-	ADJ
admet-2766	171	28	catalytic	catalytic	ADJ
admet-2766	171	29	interactions	interaction	NOUN
admet-2766	171	30	that	that	PRON
admet-2766	171	31	influence	influence	VERB
admet-2766	171	32	electrochemical	electrochemical	ADJ
admet-2766	171	33	readout	readout	NOUN
admet-2766	171	34	.	.	PUNCT
admet-2766	172	1	this	this	PRON
admet-2766	172	2	highlights	highlight	VERB
admet-2766	172	3	the	the	DET
admet-2766	172	4	potential	potential	NOUN
admet-2766	172	5	of	of	ADP
admet-2766	172	6	leveraging	leverage	VERB
admet-2766	172	7	steric	steric	ADJ
admet-2766	172	8	hindrance	hindrance	NOUN
admet-2766	172	9	mechanisms	mechanism	NOUN
admet-2766	172	10	in	in	ADP
admet-2766	172	11	crispr	crispr	NOUN
admet-2766	172	12	-	-	PUNCT
admet-2766	172	13	based	base	VERB
admet-2766	172	14	biosensors	biosensor	NOUN
admet-2766	172	15	for	for	ADP
admet-2766	172	16	highly	highly	ADV
admet-2766	172	17	specific	specific	ADJ
admet-2766	172	18	detection	detection	NOUN
admet-2766	172	19	of	of	ADP
admet-2766	172	20	point	point	NOUN
admet-2766	172	21	mutations	mutation	NOUN
admet-2766	172	22	.	.	PUNCT
admet-2766	173	1	conclusions	conclusion	NOUN
admet-2766	173	2	in	in	ADP
admet-2766	173	3	this	this	DET
admet-2766	173	4	study	study	NOUN
admet-2766	173	5	,	,	PUNCT
admet-2766	173	6	we	we	PRON
admet-2766	173	7	successfully	successfully	ADV
admet-2766	173	8	developed	develop	VERB
admet-2766	173	9	a	a	DET
admet-2766	173	10	crispr	crispr	ADJ
admet-2766	173	11	/	/	SYM
admet-2766	173	12	cas9	cas9	NOUN
admet-2766	173	13	-	-	PUNCT
admet-2766	173	14	based	base	VERB
admet-2766	173	15	electrochemical	electrochemical	ADJ
admet-2766	173	16	biosensor	biosensor	NOUN
admet-2766	173	17	capable	capable	ADJ
admet-2766	173	18	of	of	ADP
admet-2766	173	19	detecting	detect	VERB
admet-2766	173	20	katg	katg	PROPN
admet-2766	173	21	gene	gene	NOUN
admet-2766	173	22	mutations	mutation	NOUN
admet-2766	173	23	associated	associate	VERB
admet-2766	173	24	with	with	ADP
admet-2766	173	25	isoniazid	isoniazid	NOUN
admet-2766	173	26	resistance	resistance	NOUN
admet-2766	173	27	in	in	ADP
admet-2766	173	28	multidrug	multidrug	NOUN
admet-2766	173	29	-	-	PUNCT
admet-2766	173	30	resistant	resistant	ADJ
admet-2766	173	31	mycobacterium	mycobacterium	NOUN
admet-2766	173	32	tuberculosis	tuberculosis	NOUN
admet-2766	173	33	(	(	PUNCT
admet-2766	173	34	mdr	mdr	NOUN
admet-2766	173	35	-	-	NOUN
admet-2766	173	36	tb	tb	NOUN
admet-2766	173	37	)	)	PUNCT
admet-2766	173	38	.	.	PUNCT
admet-2766	174	1	by	by	ADP
admet-2766	174	2	designing	design	VERB
admet-2766	174	3	a	a	DET
admet-2766	174	4	guide	guide	NOUN
admet-2766	174	5	rna	rna	NOUN
admet-2766	174	6	with	with	ADP
admet-2766	174	7	high	high	ADJ
admet-2766	174	8	specificity	specificity	NOUN
admet-2766	174	9	(	(	PUNCT
admet-2766	174	10	on	on	ADP
admet-2766	174	11	-	-	PUNCT
admet-2766	174	12	target	target	NOUN
admet-2766	174	13	score	score	NOUN
admet-2766	174	14	of	of	ADP
admet-2766	174	15	61.2	61.2	NUM
admet-2766	174	16	and	and	CCONJ
admet-2766	174	17	off	off	ADP
admet-2766	174	18	-	-	PUNCT
admet-2766	174	19	target	target	NOUN
admet-2766	174	20	score	score	NOUN
admet-2766	174	21	of	of	ADP
admet-2766	174	22	49.0	49.0	NUM
admet-2766	174	23	)	)	PUNCT
admet-2766	174	24	targeting	target	VERB
admet-2766	174	25	the	the	DET
admet-2766	174	26	frequently	frequently	ADV
admet-2766	174	27	mutated	mutate	VERB
admet-2766	174	28	codon	codon	NOUN
admet-2766	174	29	315	315	NUM
admet-2766	174	30	,	,	PUNCT
admet-2766	174	31	we	we	PRON
admet-2766	174	32	ensured	ensure	VERB
admet-2766	174	33	effective	effective	ADJ
admet-2766	174	34	recognition	recognition	NOUN
admet-2766	174	35	and	and	CCONJ
admet-2766	174	36	cleavage	cleavage	NOUN
admet-2766	174	37	of	of	ADP
admet-2766	174	38	the	the	DET
admet-2766	174	39	mutant	mutant	ADJ
admet-2766	174	40	dna	dna	NOUN
admet-2766	174	41	sequence	sequence	NOUN
admet-2766	174	42	in	in	ADP
admet-2766	174	43	proximity	proximity	NOUN
admet-2766	174	44	to	to	ADP
admet-2766	174	45	the	the	DET
admet-2766	174	46	pam	pam	NOUN
admet-2766	174	47	(	(	PUNCT
admet-2766	174	48	agg	agg	PROPN
admet-2766	174	49	)	)	PUNCT
admet-2766	174	50	,	,	PUNCT
admet-2766	174	51	a	a	DET
admet-2766	174	52	key	key	ADJ
admet-2766	174	53	factor	factor	NOUN
admet-2766	174	54	for	for	ADP
admet-2766	174	55	cas9	cas9	NOUN
admet-2766	174	56	activity	activity	NOUN
admet-2766	174	57	.	.	PUNCT
admet-2766	175	1	the	the	DET
admet-2766	175	2	biosensor	biosensor	NOUN
admet-2766	175	3	employed	employ	VERB
admet-2766	175	4	a	a	DET
admet-2766	175	5	gold	gold	NOUN
admet-2766	175	6	-	-	PUNCT
admet-2766	175	7	modified	modify	VERB
admet-2766	175	8	screen	screen	NOUN
admet-2766	175	9	-	-	PUNCT
admet-2766	175	10	printed	print	VERB
admet-2766	175	11	carbon	carbon	NOUN
admet-2766	175	12	electrode	electrode	NOUN
admet-2766	175	13	(	(	PUNCT
admet-2766	175	14	spce	spce	PROPN
admet-2766	175	15	/	/	SYM
admet-2766	175	16	au	au	PROPN
admet-2766	175	17	)	)	PUNCT
admet-2766	175	18	,	,	PUNCT
admet-2766	175	19	functionalized	functionalize	VERB
admet-2766	175	20	via	via	ADP
admet-2766	175	21	streptavidin	streptavidin	NOUN
admet-2766	175	22	-	-	PUNCT
admet-2766	175	23	biotin	biotin	NOUN
admet-2766	175	24	interactions	interaction	NOUN
admet-2766	175	25	to	to	PART
admet-2766	175	26	immobilize	immobilize	VERB
admet-2766	175	27	a	a	DET
admet-2766	175	28	ferrocene	ferrocene	NOUN
admet-2766	175	29	-	-	PUNCT
admet-2766	175	30	labelled	label	VERB
admet-2766	175	31	dna	dna	PROPN
admet-2766	175	32	probe	probe	NOUN
admet-2766	175	33	.	.	PUNCT
admet-2766	176	1	upon	upon	SCONJ
admet-2766	176	2	hybridization	hybridization	NOUN
admet-2766	176	3	with	with	ADP
admet-2766	176	4	the	the	DET
admet-2766	176	5	target	target	NOUN
admet-2766	176	6	mutant	mutant	NOUN
admet-2766	176	7	dna	dna	NOUN
admet-2766	176	8	,	,	PUNCT
admet-2766	176	9	the	the	DET
admet-2766	176	10	cas9	cas9	NOUN
admet-2766	176	11	/	/	SYM
admet-2766	176	12	grna	grna	NOUN
admet-2766	176	13	complex	complex	NOUN
admet-2766	176	14	cleaved	cleave	VERB
admet-2766	176	15	the	the	DET
admet-2766	176	16	resulting	result	VERB
admet-2766	176	17	double	double	ADV
admet-2766	176	18	-	-	PUNCT
admet-2766	176	19	stranded	strand	VERB
admet-2766	176	20	dna	dna	NOUN
admet-2766	176	21	,	,	PUNCT
admet-2766	176	22	leading	lead	VERB
admet-2766	176	23	to	to	ADP
admet-2766	176	24	a	a	DET
admet-2766	176	25	significant	significant	ADJ
admet-2766	176	26	reduction	reduction	NOUN
admet-2766	176	27	in	in	ADP
admet-2766	176	28	ferrocene	ferrocene	NOUN
admet-2766	176	29	oxidation	oxidation	NOUN
admet-2766	176	30	signal	signal	NOUN
admet-2766	176	31	,	,	PUNCT
admet-2766	176	32	which	which	PRON
admet-2766	176	33	was	be	AUX
admet-2766	176	34	measured	measure	VERB
admet-2766	176	35	electrochemically	electrochemically	ADV
admet-2766	176	36	using	use	VERB
admet-2766	176	37	swv	swv	PROPN
admet-2766	176	38	.	.	PUNCT
admet-2766	177	1	this	this	DET
admet-2766	177	2	sensor	sensor	NOUN
admet-2766	177	3	demonstrated	demonstrate	VERB
admet-2766	177	4	exceptional	exceptional	ADJ
admet-2766	177	5	analytical	analytical	ADJ
admet-2766	177	6	performance	performance	NOUN
admet-2766	177	7	,	,	PUNCT
admet-2766	177	8	with	with	ADP
admet-2766	177	9	a	a	DET
admet-2766	177	10	detection	detection	NOUN
admet-2766	177	11	limit	limit	NOUN
admet-2766	177	12	as	as	ADV
admet-2766	177	13	low	low	ADJ
admet-2766	177	14	as	as	ADP
admet-2766	177	15	7.5530	7.5530	NUM
admet-2766	177	16	am	am	NOUN
admet-2766	177	17	and	and	CCONJ
admet-2766	177	18	a	a	DET
admet-2766	177	19	linear	linear	ADJ
admet-2766	177	20	dynamic	dynamic	ADJ
admet-2766	177	21	range	range	NOUN
admet-2766	177	22	spanning	span	VERB
admet-2766	177	23	six	six	NUM
admet-2766	177	24	orders	order	NOUN
admet-2766	177	25	of	of	ADP
admet-2766	177	26	magnitude	magnitude	NOUN
admet-2766	177	27	(	(	PUNCT
admet-2766	177	28	101	101	NUM
admet-2766	177	29	to	to	PART
admet-2766	177	30	106	106	NUM
admet-2766	177	31	am	am	NOUN
admet-2766	177	32	)	)	PUNCT
admet-2766	177	33	.	.	PUNCT
admet-2766	178	1	the	the	DET
admet-2766	178	2	system	system	NOUN
admet-2766	178	3	effectively	effectively	ADV
admet-2766	178	4	discriminated	discriminate	VERB
admet-2766	178	5	mutant	mutant	NOUN
admet-2766	178	6	from	from	ADP
admet-2766	178	7	wildtype	wildtype	NOUN
admet-2766	178	8	sequences	sequence	NOUN
admet-2766	178	9	;	;	PUNCT
admet-2766	178	10	only	only	ADV
admet-2766	178	11	the	the	DET
admet-2766	178	12	mutant	mutant	ADJ
admet-2766	178	13	target	target	NOUN
admet-2766	178	14	induced	induce	VERB
admet-2766	178	15	cas9	cas9	NOUN
admet-2766	178	16	-	-	PUNCT
admet-2766	178	17	mediated	mediate	VERB
admet-2766	178	18	cleavage	cleavage	NOUN
admet-2766	178	19	and	and	CCONJ
admet-2766	178	20	signal	signal	ADJ
admet-2766	178	21	reduction	reduction	NOUN
admet-2766	178	22	.	.	PUNCT
admet-2766	179	1	in	in	ADP
admet-2766	179	2	contrast	contrast	NOUN
admet-2766	179	3	,	,	PUNCT
admet-2766	179	4	admet	admet	PROPN
admet-2766	179	5	&	&	CCONJ
admet-2766	179	6	dmpk	dmpk	PROPN
admet-2766	179	7	13(3	13(3	NUM
admet-2766	179	8	)	)	PUNCT
admet-2766	179	9	(	(	PUNCT
admet-2766	179	10	2025	2025	NUM
admet-2766	179	11	)	)	PUNCT
admet-2766	179	12	2766	2766	NUM
admet-2766	179	13	crispr	crispr	ADJ
admet-2766	179	14	/	/	SYM
admet-2766	179	15	cas9	cas9	NOUN
admet-2766	179	16	biosensor	biosensor	NOUN
admet-2766	179	17	for	for	ADP
admet-2766	179	18	the	the	DET
admet-2766	179	19	detection	detection	NOUN
admet-2766	179	20	of	of	ADP
admet-2766	179	21	katg	katg	PROPN
admet-2766	179	22	gene	gene	NOUN
admet-2766	179	23	mutations	mutation	NOUN
admet-2766	179	24	doi	doi	NOUN
admet-2766	179	25	:	:	PUNCT
admet-2766	179	26	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	NOUN
admet-2766	179	27	11	11	NUM
admet-2766	179	28	despite	despite	SCONJ
admet-2766	179	29	not	not	PART
admet-2766	179	30	being	be	AUX
admet-2766	179	31	cleaved	cleave	VERB
admet-2766	179	32	,	,	PUNCT
admet-2766	179	33	the	the	DET
admet-2766	179	34	wild	wild	ADJ
admet-2766	179	35	-	-	PUNCT
admet-2766	179	36	type	type	NOUN
admet-2766	179	37	target	target	NOUN
admet-2766	179	38	also	also	ADV
admet-2766	179	39	led	lead	VERB
admet-2766	179	40	to	to	PART
admet-2766	179	41	signal	signal	VERB
admet-2766	179	42	suppression	suppression	NOUN
admet-2766	179	43	,	,	PUNCT
admet-2766	179	44	likely	likely	ADJ
admet-2766	179	45	due	due	ADP
admet-2766	179	46	to	to	ADP
admet-2766	179	47	stable	stable	ADJ
admet-2766	179	48	binding	binding	NOUN
admet-2766	179	49	of	of	ADP
admet-2766	179	50	the	the	DET
admet-2766	179	51	cas9	cas9	NOUN
admet-2766	179	52	/	/	SYM
admet-2766	179	53	grna	grna	NOUN
admet-2766	179	54	complex	complex	NOUN
admet-2766	179	55	and	and	CCONJ
admet-2766	179	56	resulting	result	VERB
admet-2766	179	57	steric	steric	ADJ
admet-2766	179	58	hindrance	hindrance	NOUN
admet-2766	179	59	that	that	PRON
admet-2766	179	60	impeded	impede	VERB
admet-2766	179	61	electron	electron	NOUN
admet-2766	179	62	transfer	transfer	NOUN
admet-2766	179	63	.	.	PUNCT
admet-2766	180	1	this	this	DET
admet-2766	180	2	observation	observation	NOUN
admet-2766	180	3	was	be	AUX
admet-2766	180	4	supported	support	VERB
admet-2766	180	5	by	by	ADP
admet-2766	180	6	eis	eis	PROPN
admet-2766	180	7	data	data	PROPN
admet-2766	180	8	,	,	PUNCT
admet-2766	180	9	which	which	PRON
admet-2766	180	10	showed	show	VERB
admet-2766	180	11	a	a	DET
admet-2766	180	12	significantly	significantly	ADV
admet-2766	180	13	higher	high	ADJ
admet-2766	180	14	rct	rct	PROPN
admet-2766	180	15	for	for	ADP
admet-2766	180	16	the	the	DET
admet-2766	180	17	wild	wild	ADJ
admet-2766	180	18	-	-	PUNCT
admet-2766	180	19	type	type	NOUN
admet-2766	180	20	target	target	NOUN
admet-2766	180	21	compared	compare	VERB
admet-2766	180	22	to	to	ADP
admet-2766	180	23	the	the	DET
admet-2766	180	24	mutant	mutant	ADJ
admet-2766	180	25	target	target	NOUN
admet-2766	180	26	,	,	PUNCT
admet-2766	180	27	confirming	confirm	VERB
admet-2766	180	28	greater	great	ADJ
admet-2766	180	29	electron	electron	NOUN
admet-2766	180	30	transfer	transfer	NOUN
admet-2766	180	31	obstruction	obstruction	NOUN
admet-2766	180	32	by	by	ADP
admet-2766	180	33	the	the	DET
admet-2766	180	34	non	non	ADJ
admet-2766	180	35	-	-	ADJ
admet-2766	180	36	cleaved	cleaved	ADJ
admet-2766	180	37	cas9	cas9	NOUN
admet-2766	180	38	/	/	SYM
admet-2766	180	39	grna	grna	NOUN
admet-2766	180	40	/	/	SYM
admet-2766	180	41	dna	dna	NOUN
admet-2766	180	42	complex	complex	NOUN
admet-2766	180	43	.	.	PUNCT
admet-2766	181	1	this	this	DET
admet-2766	181	2	outcome	outcome	NOUN
admet-2766	181	3	underscores	underscore	VERB
admet-2766	181	4	the	the	DET
admet-2766	181	5	sensor	sensor	NOUN
admet-2766	181	6	’s	’s	PART
admet-2766	181	7	high	high	ADJ
admet-2766	181	8	specificity	specificity	NOUN
admet-2766	181	9	and	and	CCONJ
admet-2766	181	10	capacity	capacity	NOUN
admet-2766	181	11	to	to	PART
admet-2766	181	12	detect	detect	VERB
admet-2766	181	13	single	single	ADJ
admet-2766	181	14	-	-	PUNCT
admet-2766	181	15	nucleotide	nucleotide	NOUN
admet-2766	181	16	variations	variation	NOUN
admet-2766	181	17	based	base	VERB
admet-2766	181	18	on	on	ADP
admet-2766	181	19	catalytic	catalytic	ADJ
admet-2766	181	20	and	and	CCONJ
admet-2766	181	21	non	non	ADJ
admet-2766	181	22	-	-	ADJ
admet-2766	181	23	catalytic	catalytic	ADJ
admet-2766	181	24	interactions	interaction	NOUN
admet-2766	181	25	.	.	PUNCT
admet-2766	182	1	these	these	DET
admet-2766	182	2	findings	finding	NOUN
admet-2766	182	3	highlight	highlight	VERB
admet-2766	182	4	the	the	DET
admet-2766	182	5	potential	potential	NOUN
admet-2766	182	6	of	of	ADP
admet-2766	182	7	integrating	integrate	VERB
admet-2766	182	8	crispr	crispr	ADJ
admet-2766	182	9	/	/	SYM
admet-2766	182	10	cas9	cas9	NOUN
admet-2766	182	11	-	-	PUNCT
admet-2766	182	12	based	base	VERB
admet-2766	182	13	molecular	molecular	ADJ
admet-2766	182	14	recognition	recognition	NOUN
admet-2766	182	15	with	with	ADP
admet-2766	182	16	electrochemical	electrochemical	ADJ
admet-2766	182	17	transduction	transduction	NOUN
admet-2766	182	18	to	to	PART
admet-2766	182	19	develop	develop	VERB
admet-2766	182	20	a	a	DET
admet-2766	182	21	diagnostic	diagnostic	ADJ
admet-2766	182	22	platform	platform	NOUN
admet-2766	182	23	for	for	ADP
admet-2766	182	24	drug	drug	NOUN
admet-2766	182	25	-	-	PUNCT
admet-2766	182	26	resistant	resistant	ADJ
admet-2766	182	27	tb	tb	NOUN
admet-2766	182	28	,	,	PUNCT
admet-2766	182	29	while	while	SCONJ
admet-2766	182	30	also	also	ADV
admet-2766	182	31	addressing	address	VERB
admet-2766	182	32	a	a	DET
admet-2766	182	33	critical	critical	ADJ
admet-2766	182	34	diagnostic	diagnostic	ADJ
admet-2766	182	35	gap	gap	NOUN
admet-2766	182	36	by	by	ADP
admet-2766	182	37	enabling	enable	VERB
admet-2766	182	38	differentiation	differentiation	NOUN
admet-2766	182	39	between	between	ADP
admet-2766	182	40	tb	tb	NOUN
admet-2766	182	41	and	and	CCONJ
admet-2766	182	42	mdr	mdr	PROPN
admet-2766	182	43	-	-	PROPN
admet-2766	182	44	tb	tb	X
admet-2766	182	45	with	with	ADP
admet-2766	182	46	isoniazid	isoniazid	NOUN
admet-2766	182	47	resistance	resistance	NOUN
admet-2766	182	48	,	,	PUNCT
admet-2766	182	49	offering	offer	VERB
admet-2766	182	50	significant	significant	ADJ
admet-2766	182	51	implications	implication	NOUN
admet-2766	182	52	for	for	ADP
admet-2766	182	53	improving	improve	VERB
admet-2766	182	54	treatment	treatment	NOUN
admet-2766	182	55	decisions	decision	NOUN
admet-2766	182	56	,	,	PUNCT
admet-2766	182	57	particularly	particularly	ADV
admet-2766	182	58	in	in	ADP
admet-2766	182	59	clinical	clinical	ADJ
admet-2766	182	60	and	and	CCONJ
admet-2766	182	61	resource	resource	NOUN
admet-2766	182	62	-	-	PUNCT
admet-2766	182	63	limited	limit	VERB
admet-2766	182	64	settings	setting	NOUN
admet-2766	182	65	.	.	PUNCT
admet-2766	183	1	the	the	DET
admet-2766	183	2	approach	approach	NOUN
admet-2766	183	3	offers	offer	VERB
admet-2766	183	4	advantages	advantage	NOUN
admet-2766	183	5	in	in	ADP
admet-2766	183	6	speed	speed	NOUN
admet-2766	183	7	,	,	PUNCT
admet-2766	183	8	portability	portability	NOUN
admet-2766	183	9	,	,	PUNCT
admet-2766	183	10	and	and	CCONJ
admet-2766	183	11	cost	cost	NOUN
admet-2766	183	12	-	-	PUNCT
admet-2766	183	13	effectiveness	effectiveness	NOUN
admet-2766	183	14	compared	compare	VERB
admet-2766	183	15	to	to	ADP
admet-2766	183	16	conventional	conventional	ADJ
admet-2766	183	17	molecular	molecular	ADJ
admet-2766	183	18	assays	assay	NOUN
admet-2766	183	19	.	.	PUNCT
admet-2766	184	1	with	with	ADP
admet-2766	184	2	further	further	ADJ
admet-2766	184	3	validation	validation	NOUN
admet-2766	184	4	using	use	VERB
admet-2766	184	5	clinical	clinical	ADJ
admet-2766	184	6	samples	sample	NOUN
admet-2766	184	7	and	and	CCONJ
admet-2766	184	8	potential	potential	ADJ
admet-2766	184	9	integration	integration	NOUN
admet-2766	184	10	into	into	ADP
admet-2766	184	11	point	point	NOUN
admet-2766	184	12	-	-	PUNCT
admet-2766	184	13	of	of	ADP
admet-2766	184	14	-	-	PUNCT
admet-2766	184	15	care	care	NOUN
admet-2766	184	16	devices	device	NOUN
admet-2766	184	17	,	,	PUNCT
admet-2766	184	18	this	this	DET
admet-2766	184	19	biosensor	biosensor	NOUN
admet-2766	184	20	could	could	AUX
admet-2766	184	21	significantly	significantly	ADV
admet-2766	184	22	contribute	contribute	VERB
admet-2766	184	23	to	to	ADP
admet-2766	184	24	the	the	DET
admet-2766	184	25	early	early	ADJ
admet-2766	184	26	detection	detection	NOUN
admet-2766	184	27	and	and	CCONJ
admet-2766	184	28	management	management	NOUN
admet-2766	184	29	of	of	ADP
admet-2766	184	30	mdr	mdr	PROPN
admet-2766	184	31	-	-	PROPN
admet-2766	184	32	tb	tb	PROPN
admet-2766	184	33	.	.	PUNCT
admet-2766	184	34	supplementary	supplementary	ADJ
admet-2766	184	35	material	material	NOUN
admet-2766	184	36	additional	additional	ADJ
admet-2766	184	37	data	datum	NOUN
admet-2766	184	38	are	be	AUX
admet-2766	184	39	available	available	ADJ
admet-2766	184	40	at	at	ADP
admet-2766	184	41	https://pub.iapchem.org/ojs/index.php/admet/article/view/2766	https://pub.iapchem.org/ojs/index.php/admet/article/view/2766	ADJ
admet-2766	184	42	,	,	PUNCT
admet-2766	184	43	or	or	CCONJ
admet-2766	184	44	from	from	ADP
admet-2766	184	45	the	the	DET
admet-2766	184	46	corresponding	corresponding	ADJ
admet-2766	184	47	author	author	NOUN
admet-2766	184	48	on	on	ADP
admet-2766	184	49	request	request	NOUN
admet-2766	184	50	.	.	PUNCT
admet-2766	185	1	acknowledgements	acknowledgement	NOUN
admet-2766	185	2	:	:	PUNCT
admet-2766	185	3	irkham	irkham	NOUN
admet-2766	185	4	thank	thank	NOUN
admet-2766	185	5	to	to	PART
admet-2766	185	6	direktorat	direktorat	PROPN
admet-2766	185	7	penelitian	penelitian	PROPN
admet-2766	185	8	dan	dan	PROPN
admet-2766	185	9	pengabdian	pengabdian	PROPN
admet-2766	185	10	masyarakat	masyarakat	PROPN
admet-2766	185	11	direktorat	direktorat	PROPN
admet-2766	185	12	jenderal	jenderal	PROPN
admet-2766	185	13	riset	riset	PROPN
admet-2766	185	14	dan	dan	PROPN
admet-2766	185	15	pengembangan	pengembangan	PROPN
admet-2766	185	16	with	with	ADP
admet-2766	185	17	the	the	DET
admet-2766	185	18	scheme	scheme	NOUN
admet-2766	185	19	penelitian	penelitian	PROPN
admet-2766	185	20	fundametal	fundametal	PROPN
admet-2766	185	21	reguler	reguler	NOUN
admet-2766	185	22	(	(	PUNCT
admet-2766	185	23	pfr	pfr	PROPN
admet-2766	185	24	,	,	PUNCT
admet-2766	185	25	no	no	INTJ
admet-2766	185	26	.	.	NOUN
admet-2766	185	27	093	093	NUM
admet-2766	185	28	/	/	SYM
admet-2766	185	29	c3	c3	PROPN
admet-2766	185	30	/	/	SYM
admet-2766	185	31	dt.05.00	dt.05.00	PROPN
admet-2766	185	32	/	/	SYM
admet-2766	185	33	pl/2025	pl/2025	ADJ
admet-2766	185	34	;	;	PUNCT
admet-2766	185	35	1580	1580	NUM
admet-2766	185	36	/	/	SYM
admet-2766	185	37	un6.3.1	un6.3.1	PROPN
admet-2766	185	38	/	/	SYM
admet-2766	185	39	pt.00/2025	pt.00/2025	NOUN
admet-2766	185	40	)	)	PUNCT
admet-2766	185	41	for	for	SCONJ
admet-2766	185	42	the	the	DET
admet-2766	185	43	funding	funding	NOUN
admet-2766	185	44	to	to	PART
admet-2766	185	45	support	support	VERB
admet-2766	185	46	this	this	DET
admet-2766	185	47	article	article	NOUN
admet-2766	185	48	preparation	preparation	NOUN
admet-2766	185	49	.	.	PUNCT
admet-2766	186	1	yeni	yeni	PROPN
admet-2766	186	2	wahyuni	wahyuni	PROPN
admet-2766	186	3	hartati	hartati	PROPN
admet-2766	186	4	would	would	AUX
admet-2766	186	5	also	also	ADV
admet-2766	186	6	thank	thank	VERB
admet-2766	186	7	universitas	universita	NOUN
admet-2766	186	8	padjadjaran	padjadjaran	VERB
admet-2766	186	9	with	with	ADP
admet-2766	186	10	the	the	DET
admet-2766	186	11	scheme	scheme	NOUN
admet-2766	186	12	academic	academic	ADJ
admet-2766	186	13	leadership	leadership	NOUN
admet-2766	186	14	grant	grant	NOUN
admet-2766	186	15	of	of	ADP
admet-2766	186	16	padjadjaran	padjadjaran	PROPN
admet-2766	186	17	university	university	PROPN
admet-2766	186	18	(	(	PUNCT
admet-2766	186	19	no	no	INTJ
admet-2766	186	20	.	.	NOUN
admet-2766	186	21	1655	1655	NUM
admet-2766	186	22	/	/	SYM
admet-2766	186	23	un6.3.1	un6.3.1	ADJ
admet-2766	186	24	/	/	SYM
admet-2766	186	25	pt.00/2024	pt.00/2024	NUM
admet-2766	186	26	)	)	PUNCT
admet-2766	186	27	.	.	PUNCT
admet-2766	187	1	conflict	conflict	NOUN
admet-2766	187	2	of	of	ADP
admet-2766	187	3	interest	interest	NOUN
admet-2766	187	4	:	:	PUNCT
admet-2766	187	5	authors	author	NOUN
admet-2766	187	6	declare	declare	VERB
admet-2766	187	7	that	that	SCONJ
admet-2766	187	8	there	there	PRON
admet-2766	187	9	is	be	VERB
admet-2766	187	10	no	no	DET
admet-2766	187	11	conflict	conflict	NOUN
admet-2766	187	12	of	of	ADP
admet-2766	187	13	interest	interest	NOUN
admet-2766	187	14	.	.	PUNCT
admet-2766	188	1	author	author	NOUN
admet-2766	188	2	contribution	contribution	PROPN
admet-2766	188	3	:	:	PUNCT
admet-2766	188	4	all	all	DET
admet-2766	188	5	authors	author	NOUN
admet-2766	188	6	contributed	contribute	VERB
admet-2766	188	7	to	to	ADP
admet-2766	188	8	the	the	DET
admet-2766	188	9	study	study	NOUN
admet-2766	188	10	conception	conception	NOUN
admet-2766	188	11	and	and	CCONJ
admet-2766	188	12	design	design	NOUN
admet-2766	188	13	.	.	PUNCT
admet-2766	189	1	dika	dika	PROPN
admet-2766	189	2	apriliana	apriliana	PROPN
admet-2766	189	3	wulandari	wulandari	PROPN
admet-2766	189	4	:	:	PUNCT
admet-2766	189	5	writing	write	VERB
admet-2766	189	6	original	original	ADJ
admet-2766	189	7	draft	draft	NOUN
admet-2766	189	8	,	,	PUNCT
admet-2766	189	9	data	data	NOUN
admet-2766	189	10	curation	curation	NOUN
admet-2766	189	11	,	,	PUNCT
admet-2766	189	12	formal	formal	ADJ
admet-2766	189	13	analysis	analysis	NOUN
admet-2766	189	14	,	,	PUNCT
admet-2766	189	15	investigation	investigation	NOUN
admet-2766	189	16	,	,	PUNCT
admet-2766	189	17	visualization	visualization	NOUN
admet-2766	189	18	.	.	PUNCT
admet-2766	190	1	muhammad	muhammad	PROPN
admet-2766	190	2	ihda	ihda	PROPN
admet-2766	190	3	hamlu	hamlu	PROPN
admet-2766	190	4	liwaissunati	liwaissunati	PROPN
admet-2766	190	5	zein	zein	PROPN
admet-2766	190	6	:	:	PUNCT
admet-2766	190	7	writing	write	VERB
admet-2766	190	8	review	review	NOUN
admet-2766	190	9	and	and	CCONJ
admet-2766	190	10	editing	editing	NOUN
admet-2766	190	11	,	,	PUNCT
admet-2766	190	12	methodology	methodology	NOUN
admet-2766	190	13	,	,	PUNCT
admet-2766	190	14	visualization	visualization	NOUN
admet-2766	190	15	.	.	PUNCT
admet-2766	191	1	salma	salma	PROPN
admet-2766	191	2	nur	nur	PROPN
admet-2766	191	3	zakiyyah	zakiyyah	PROPN
admet-2766	191	4	:	:	PUNCT
admet-2766	191	5	writing	write	VERB
admet-2766	191	6	review	review	NOUN
admet-2766	191	7	and	and	CCONJ
admet-2766	191	8	editing	edit	VERB
admet-2766	191	9	,	,	PUNCT
admet-2766	191	10	formal	formal	ADJ
admet-2766	191	11	analysis	analysis	NOUN
admet-2766	191	12	,	,	PUNCT
admet-2766	191	13	software	software	NOUN
admet-2766	191	14	.	.	PUNCT
admet-2766	192	1	safri	safri	PROPN
admet-2766	192	2	ishmayana	ishmayana	PROPN
admet-2766	192	3	:	:	PUNCT
admet-2766	192	4	writing	write	VERB
admet-2766	192	5	review	review	NOUN
admet-2766	192	6	and	and	CCONJ
admet-2766	192	7	editing	editing	NOUN
admet-2766	192	8	,	,	PUNCT
admet-2766	192	9	validation	validation	NOUN
admet-2766	192	10	,	,	PUNCT
admet-2766	192	11	supervision	supervision	NOUN
admet-2766	192	12	.	.	PUNCT
admet-2766	193	1	mehmet	mehmet	PROPN
admet-2766	193	2	ozsoz	ozsoz	PROPN
admet-2766	193	3	:	:	PUNCT
admet-2766	193	4	writing	write	VERB
admet-2766	193	5	review	review	NOUN
admet-2766	193	6	and	and	CCONJ
admet-2766	193	7	editing	editing	NOUN
admet-2766	193	8	,	,	PUNCT
admet-2766	193	9	validation	validation	NOUN
admet-2766	193	10	,	,	PUNCT
admet-2766	193	11	supervision	supervision	NOUN
admet-2766	193	12	.	.	PUNCT
admet-2766	194	1	yeni	yeni	PROPN
admet-2766	194	2	wahyuni	wahyuni	PROPN
admet-2766	194	3	hartati	hartati	NOUN
admet-2766	194	4	:	:	PUNCT
admet-2766	194	5	writing	write	VERB
admet-2766	194	6	review	review	NOUN
admet-2766	194	7	and	and	CCONJ
admet-2766	194	8	editing	editing	NOUN
admet-2766	194	9	,	,	PUNCT
admet-2766	194	10	conceptualization	conceptualization	NOUN
admet-2766	194	11	,	,	PUNCT
admet-2766	194	12	funding	funding	NOUN
admet-2766	194	13	acquisition	acquisition	NOUN
admet-2766	194	14	,	,	PUNCT
admet-2766	194	15	resources	resource	NOUN
admet-2766	194	16	,	,	PUNCT
admet-2766	194	17	supervision	supervision	NOUN
admet-2766	194	18	.	.	PUNCT
admet-2766	195	1	irkham	irkham	NOUN
admet-2766	195	2	:	:	PUNCT
admet-2766	195	3	writing	write	VERB
admet-2766	195	4	review	review	NOUN
admet-2766	195	5	and	and	CCONJ
admet-2766	195	6	editing	editing	NOUN
admet-2766	195	7	,	,	PUNCT
admet-2766	195	8	conceptualization	conceptualization	NOUN
admet-2766	195	9	,	,	PUNCT
admet-2766	195	10	funding	funding	NOUN
admet-2766	195	11	acquisition	acquisition	NOUN
admet-2766	195	12	,	,	PUNCT
admet-2766	195	13	resources	resource	NOUN
admet-2766	195	14	,	,	PUNCT
admet-2766	195	15	supervision	supervision	NOUN
admet-2766	195	16	.	.	PUNCT
admet-2766	196	1	references	reference	NOUN
admet-2766	196	2	[	[	X
admet-2766	196	3	1	1	NUM
admet-2766	196	4	]	]	PUNCT
admet-2766	196	5	world	world	NOUN
admet-2766	196	6	health	health	NOUN
admet-2766	196	7	organization	organization	NOUN
admet-2766	196	8	.	.	PUNCT
admet-2766	197	1	global	global	ADJ
admet-2766	197	2	tuberculosis	tuberculosis	NOUN
admet-2766	197	3	report	report	NOUN
admet-2766	197	4	2024	2024	NUM
admet-2766	197	5	,	,	PUNCT
admet-2766	197	6	available	available	ADJ
admet-2766	197	7	at	at	ADP
admet-2766	197	8	https://doi.org/https://www.who.int/teams/global-tuberculosis-programme/tb-reports/globaltuberculosis-report-2024	https://doi.org/https://www.who.int/teams/global-tuberculosis-programme/tb-reports/globaltuberculosis-report-2024	PROPN
admet-2766	197	9	,	,	PUNCT
admet-2766	197	10	accessed	access	VERB
admet-2766	197	11	agustus	agustus	NOUN
admet-2766	197	12	2024	2024	NUM
admet-2766	197	13	[	[	X
admet-2766	197	14	2	2	NUM
admet-2766	197	15	]	]	X
admet-2766	197	16	d.a	d.a	PROPN
admet-2766	197	17	.	.	PROPN
admet-2766	197	18	wulandari	wulandari	PROPN
admet-2766	197	19	,	,	PUNCT
admet-2766	197	20	y.w	y.w	PROPN
admet-2766	197	21	.	.	PROPN
admet-2766	197	22	hartati	hartati	PROPN
admet-2766	197	23	,	,	PUNCT
admet-2766	197	24	a.u	a.u	PROPN
admet-2766	197	25	.	.	PROPN
admet-2766	197	26	ibrahim	ibrahim	PROPN
admet-2766	197	27	,	,	PUNCT
admet-2766	197	28	d.a.e	d.a.e	NOUN
admet-2766	197	29	pitaloka	pitaloka	NOUN
admet-2766	197	30	,	,	PUNCT
admet-2766	197	31	and	and	CCONJ
admet-2766	197	32	irkham	irkham	NOUN
admet-2766	197	33	.	.	PUNCT
admet-2766	198	1	multidrug	multidrug	NOUN
admet-2766	198	2	-	-	PUNCT
admet-2766	198	3	resistant	resistant	ADJ
admet-2766	198	4	tuberculosis	tuberculosis	NOUN
admet-2766	198	5	.	.	PUNCT
admet-2766	199	1	clinica	clinica	PROPN
admet-2766	199	2	chimica	chimica	PROPN
admet-2766	199	3	acta	acta	PROPN
admet-2766	199	4	559	559	NUM
admet-2766	199	5	(	(	PUNCT
admet-2766	199	6	2024	2024	NUM
admet-2766	199	7	)	)	PUNCT
admet-2766	199	8	119701	119701	NUM
admet-2766	199	9	.	.	PUNCT
admet-2766	200	1	https://doi.org/10.1016/j.cca.2024.119701	https://doi.org/10.1016/j.cca.2024.119701	PUNCT
admet-2766	201	1	[	[	X
admet-2766	201	2	3	3	NUM
admet-2766	201	3	]	]	X
admet-2766	201	4	m.	m.	NOUN
admet-2766	201	5	de	de	PROPN
admet-2766	201	6	rycker	rycker	PROPN
admet-2766	201	7	,	,	PUNCT
admet-2766	201	8	b.	b.	PROPN
admet-2766	201	9	baragaña	baragaña	PROPN
admet-2766	201	10	,	,	PUNCT
admet-2766	201	11	s.l	s.l	PROPN
admet-2766	201	12	.	.	PROPN
admet-2766	201	13	duce	duce	PROPN
admet-2766	201	14	,	,	PUNCT
admet-2766	201	15	and	and	CCONJ
admet-2766	201	16	i.h	i.h	PROPN
admet-2766	201	17	.	.	PROPN
admet-2766	201	18	gilbert	gilbert	PROPN
admet-2766	201	19	.	.	PUNCT
admet-2766	202	1	challenges	challenge	NOUN
admet-2766	202	2	and	and	CCONJ
admet-2766	202	3	recent	recent	ADJ
admet-2766	202	4	progress	progress	NOUN
admet-2766	202	5	in	in	ADP
admet-2766	202	6	drug	drug	NOUN
admet-2766	202	7	discovery	discovery	NOUN
admet-2766	202	8	for	for	ADP
admet-2766	202	9	tropical	tropical	ADJ
admet-2766	202	10	diseases	disease	NOUN
admet-2766	202	11	.	.	PUNCT
admet-2766	203	1	nature	nature	NOUN
admet-2766	203	2	559	559	NUM
admet-2766	203	3	(	(	PUNCT
admet-2766	203	4	2018	2018	NUM
admet-2766	203	5	)	)	PUNCT
admet-2766	203	6	498	498	NUM
admet-2766	203	7	-	-	SYM
admet-2766	203	8	506	506	NUM
admet-2766	203	9	.	.	PUNCT
admet-2766	204	1	https://doi.org/10.1038/s41586-018-0327-4	https://doi.org/10.1038/s41586-018-0327-4	VERB
admet-2766	205	1	[	[	X
admet-2766	205	2	4	4	X
admet-2766	205	3	]	]	X
admet-2766	205	4	v.	v.	CCONJ
admet-2766	205	5	singh	singh	PROPN
admet-2766	205	6	,	,	PUNCT
admet-2766	205	7	k.	k.	PROPN
admet-2766	205	8	chibale	chibale	PROPN
admet-2766	205	9	.	.	PUNCT
admet-2766	206	1	strategies	strategy	NOUN
admet-2766	206	2	to	to	PART
admet-2766	206	3	combat	combat	VERB
admet-2766	206	4	multi	multi	ADJ
admet-2766	206	5	-	-	ADJ
admet-2766	206	6	drug	drug	ADJ
admet-2766	206	7	resistance	resistance	NOUN
admet-2766	206	8	in	in	ADP
admet-2766	206	9	tuberculosis	tuberculosis	NOUN
admet-2766	206	10	.	.	PUNCT
admet-2766	207	1	accounts	account	NOUN
admet-2766	207	2	of	of	ADP
admet-2766	207	3	chemical	chemical	ADJ
admet-2766	207	4	research	research	NOUN
admet-2766	207	5	54	54	NUM
admet-2766	207	6	(	(	PUNCT
admet-2766	207	7	2021	2021	NUM
admet-2766	207	8	)	)	PUNCT
admet-2766	207	9	2361	2361	NUM
admet-2766	207	10	-	-	SYM
admet-2766	207	11	2376	2376	NUM
admet-2766	207	12	.	.	PUNCT
admet-2766	208	1	https://doi.org/10.1021/acs.accounts.0c00878	https://doi.org/10.1021/acs.accounts.0c00878	ADJ
admet-2766	208	2	[	[	X
admet-2766	208	3	5	5	NUM
admet-2766	208	4	]	]	PUNCT
admet-2766	208	5	l.	l.	PROPN
admet-2766	208	6	muthukrishnan	muthukrishnan	PROPN
admet-2766	208	7	.	.	PUNCT
admet-2766	209	1	multidrug	multidrug	VERB
admet-2766	209	2	resistant	resistant	ADJ
admet-2766	209	3	tuberculosis	tuberculosis	PRON
admet-2766	209	4	diagnostic	diagnostic	ADJ
admet-2766	209	5	challenges	challenge	NOUN
admet-2766	209	6	and	and	CCONJ
admet-2766	209	7	its	its	PRON
admet-2766	209	8	conquering	conquering	NOUN
admet-2766	209	9	by	by	ADP
admet-2766	209	10	nanotechnology	nanotechnology	NOUN
admet-2766	209	11	approach	approach	VERB
admet-2766	209	12	an	an	DET
admet-2766	209	13	overview	overview	NOUN
admet-2766	209	14	.	.	PUNCT
admet-2766	210	1	chemico	chemico	ADJ
admet-2766	210	2	-	-	ADJ
admet-2766	210	3	biological	biological	ADJ
admet-2766	210	4	interactions	interaction	NOUN
admet-2766	210	5	337	337	NUM
admet-2766	210	6	(	(	PUNCT
admet-2766	210	7	2021	2021	NUM
admet-2766	210	8	)	)	PUNCT
admet-2766	210	9	109397	109397	NUM
admet-2766	210	10	.	.	PUNCT
admet-2766	211	1	https://doi.org/10.1016/j.cbi.2021.109397	https://doi.org/10.1016/j.cbi.2021.109397	PUNCT
admet-2766	212	1	[	[	X
admet-2766	212	2	6	6	NUM
admet-2766	212	3	]	]	PUNCT
admet-2766	212	4	a.	a.	NOUN
admet-2766	212	5	jain	jain	PROPN
admet-2766	212	6	,	,	PUNCT
admet-2766	212	7	p	p	PROPN
admet-2766	212	8	dixit	dixit	PROPN
admet-2766	212	9	.	.	PUNCT
admet-2766	213	1	multidrug	multidrug	VERB
admet-2766	213	2	resistant	resistant	ADJ
admet-2766	213	3	to	to	ADP
admet-2766	213	4	extensively	extensively	ADV
admet-2766	213	5	drug	drug	VERB
admet-2766	213	6	resistant	resistant	ADJ
admet-2766	213	7	tuberculosis	tuberculosis	NOUN
admet-2766	213	8	:	:	PUNCT
admet-2766	213	9	what	what	PRON
admet-2766	213	10	is	be	AUX
admet-2766	213	11	next	next	ADJ
admet-2766	213	12	?	?	PUNCT
admet-2766	214	1	journal	journal	NOUN
admet-2766	214	2	of	of	ADP
admet-2766	214	3	biosciences	bioscience	NOUN
admet-2766	214	4	33	33	NUM
admet-2766	214	5	(	(	PUNCT
admet-2766	214	6	2008	2008	NUM
admet-2766	214	7	)	)	PUNCT
admet-2766	214	8	605	605	NUM
admet-2766	214	9	-	-	SYM
admet-2766	214	10	616	616	NUM
admet-2766	214	11	.	.	PUNCT
admet-2766	214	12	https://doi.org/10.1007/s12038-008-0078-8	https://doi.org/10.1007/s12038-008-0078-8	NUM
admet-2766	214	13	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	214	14	https://pub.iapchem.org/ojs/index.php/admet/article/view/2766	https://pub.iapchem.org/ojs/index.php/admet/article/view/2766	PROPN
admet-2766	214	15	https://doi.org/https:/www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2024	https://doi.org/https:/www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2024	PROPN
admet-2766	214	16	https://doi.org/https:/www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2024	https://doi.org/https:/www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2024	PROPN
admet-2766	214	17	https://doi.org/10.1016/j.cca.2024.119701	https://doi.org/10.1016/j.cca.2024.119701	PROPN
admet-2766	214	18	https://doi.org/10.1038/s41586-018-0327-4	https://doi.org/10.1038/s41586-018-0327-4	NOUN
admet-2766	215	1	https://doi.org/10.1021/acs.accounts.0c00878	https://doi.org/10.1021/acs.accounts.0c00878	NOUN
admet-2766	215	2	https://doi.org/10.1016/j.cbi.2021.109397	https://doi.org/10.1016/j.cbi.2021.109397	PROPN
admet-2766	215	3	https://doi.org/10.1007/s12038-008-0078-8	https://doi.org/10.1007/s12038-008-0078-8	NUM
admet-2766	215	4	d.	d.	PROPN
admet-2766	215	5	a.	a.	PROPN
admet-2766	215	6	wulandari	wulandari	PROPN
admet-2766	215	7	et	et	PROPN
admet-2766	215	8	al	al	PROPN
admet-2766	215	9	.	.	PROPN
admet-2766	215	10	admet	admet	PROPN
admet-2766	215	11	&	&	CCONJ
admet-2766	215	12	dmpk	dmpk	PROPN
admet-2766	215	13	13(3	13(3	NUM
admet-2766	215	14	)	)	PUNCT
admet-2766	215	15	(	(	PUNCT
admet-2766	215	16	2025	2025	NUM
admet-2766	215	17	)	)	PUNCT
admet-2766	215	18	2766	2766	NUM
admet-2766	215	19	12	12	NUM
admet-2766	216	1	[	[	X
admet-2766	216	2	7	7	X
admet-2766	216	3	]	]	X
admet-2766	216	4	j.l	j.l	PROPN
admet-2766	216	5	.	.	PROPN
admet-2766	216	6	khawbung	khawbung	PROPN
admet-2766	216	7	,	,	PUNCT
admet-2766	216	8	d.	d.	PROPN
admet-2766	216	9	nath	nath	PROPN
admet-2766	216	10	,	,	PUNCT
admet-2766	216	11	and	and	CCONJ
admet-2766	216	12	s.	s.	PROPN
admet-2766	216	13	chakraborty	chakraborty	PROPN
admet-2766	216	14	,	,	PUNCT
admet-2766	216	15	drug	drug	NOUN
admet-2766	216	16	resistant	resistant	ADJ
admet-2766	216	17	tuberculosis	tuberculosis	NOUN
admet-2766	216	18	:	:	PUNCT
admet-2766	216	19	a	a	DET
admet-2766	216	20	review	review	NOUN
admet-2766	216	21	.	.	PUNCT
admet-2766	217	1	comparative	comparative	ADJ
admet-2766	217	2	immunology	immunology	NOUN
admet-2766	217	3	,	,	PUNCT
admet-2766	217	4	microbiology	microbiology	NOUN
admet-2766	217	5	and	and	CCONJ
admet-2766	217	6	infectious	infectious	ADJ
admet-2766	217	7	diseases	disease	NOUN
admet-2766	217	8	74	74	NUM
admet-2766	217	9	(	(	PUNCT
admet-2766	217	10	2021	2021	NUM
admet-2766	217	11	)	)	PUNCT
admet-2766	217	12	101574	101574	NUM
admet-2766	217	13	.	.	PUNCT
admet-2766	218	1	https://doi.org/10.1016/j.cimid.2020.101574	https://doi.org/10.1016/j.cimid.2020.101574	NOUN
admet-2766	218	2	[	[	X
admet-2766	218	3	8	8	X
admet-2766	218	4	]	]	X
admet-2766	218	5	j.g	j.g	PROPN
admet-2766	218	6	.	.	PROPN
admet-2766	218	7	jang	jang	PROPN
admet-2766	218	8	,	,	PUNCT
admet-2766	218	9	j.h	j.h	PROPN
admet-2766	218	10	.	.	PROPN
admet-2766	218	11	chung	chung	PROPN
admet-2766	218	12	.	.	PUNCT
admet-2766	218	13	diagnosis	diagnosis	NOUN
admet-2766	218	14	and	and	CCONJ
admet-2766	218	15	treatment	treatment	NOUN
admet-2766	218	16	of	of	ADP
admet-2766	218	17	multidrug	multidrug	NOUN
admet-2766	218	18	-	-	PUNCT
admet-2766	218	19	resistant	resistant	ADJ
admet-2766	218	20	tuberculosis	tuberculosis	NOUN
admet-2766	218	21	.	.	PUNCT
admet-2766	219	1	yeungnam	yeungnam	PROPN
admet-2766	219	2	university	university	PROPN
admet-2766	219	3	journal	journal	NOUN
admet-2766	219	4	of	of	ADP
admet-2766	219	5	medicine	medicine	NOUN
admet-2766	219	6	34	34	NUM
admet-2766	219	7	(	(	PUNCT
admet-2766	219	8	2020	2020	NUM
admet-2766	219	9	)	)	PUNCT
admet-2766	219	10	277	277	NUM
admet-2766	219	11	-	-	SYM
admet-2766	219	12	285	285	NUM
admet-2766	219	13	.	.	PUNCT
admet-2766	220	1	https://doi.org/10.12701/yujm.2020.00626	https://doi.org/10.12701/yujm.2020.00626	PROPN
admet-2766	221	1	[	[	X
admet-2766	221	2	9	9	NUM
admet-2766	221	3	]	]	X
admet-2766	221	4	e.	e.	PROPN
admet-2766	221	5	rivière	rivière	PROPN
admet-2766	221	6	,	,	PUNCT
admet-2766	221	7	m.g	m.g	PROPN
admet-2766	221	8	.	.	PROPN
admet-2766	221	9	whitfield	whitfield	PROPN
admet-2766	221	10	,	,	PUNCT
admet-2766	221	11	j.	j.	PROPN
admet-2766	221	12	nelen	nelen	PROPN
admet-2766	221	13	,	,	PUNCT
admet-2766	221	14	t.h	t.h	PROPN
admet-2766	221	15	.	.	PROPN
admet-2766	221	16	heupink	heupink	PROPN
admet-2766	221	17	,	,	PUNCT
admet-2766	221	18	a.v	a.v	PROPN
admet-2766	221	19	.	.	PROPN
admet-2766	221	20	rie	rie	PROPN
admet-2766	221	21	.	.	PUNCT
admet-2766	221	22	identifying	identify	VERB
admet-2766	221	23	isoniazid	isoniazid	NOUN
admet-2766	221	24	resistance	resistance	NOUN
admet-2766	221	25	makers	maker	NOUN
admet-2766	221	26	to	to	PART
admet-2766	221	27	guide	guide	VERB
admet-2766	221	28	inclusion	inclusion	NOUN
admet-2766	221	29	of	of	ADP
admet-2766	221	30	high	high	ADJ
admet-2766	221	31	-	-	PUNCT
admet-2766	221	32	dose	dose	NOUN
admet-2766	221	33	isoniazid	isoniazid	NOUN
admet-2766	221	34	in	in	ADP
admet-2766	221	35	tuberculosis	tuberculosis	NOUN
admet-2766	221	36	treatment	treatment	NOUN
admet-2766	221	37	regimens	regimen	NOUN
admet-2766	221	38	.	.	PUNCT
admet-2766	222	1	clinical	clinical	ADJ
admet-2766	222	2	microbiology	microbiology	NOUN
admet-2766	222	3	and	and	CCONJ
admet-2766	222	4	infection	infection	NOUN
admet-2766	222	5	26	26	NUM
admet-2766	222	6	(	(	PUNCT
admet-2766	222	7	2020	2020	NUM
admet-2766	222	8	)	)	PUNCT
admet-2766	222	9	1332	1332	NUM
admet-2766	222	10	-	-	SYM
admet-2766	222	11	1337	1337	NUM
admet-2766	222	12	.	.	PUNCT
admet-2766	223	1	https://doi.org/10.1016/j.cmi.2020.07.004	https://doi.org/10.1016/j.cmi.2020.07.004	NOUN
admet-2766	224	1	[	[	X
admet-2766	224	2	10	10	NUM
admet-2766	224	3	]	]	X
admet-2766	224	4	c.	c.	PROPN
admet-2766	224	5	metcalfe	metcalfe	PROPN
admet-2766	224	6	,	,	PUNCT
admet-2766	224	7	i.k	i.k	PROPN
admet-2766	224	8	.	.	PROPN
admet-2766	224	9	macdonald	macdonald	PROPN
admet-2766	224	10	,	,	PUNCT
admet-2766	224	11	e.j	e.j	PROPN
admet-2766	224	12	.	.	PROPN
admet-2766	224	13	murphy	murphy	PROPN
admet-2766	224	14	,	,	PUNCT
admet-2766	224	15	k.a	k.a	PROPN
admet-2766	224	16	.	.	PROPN
admet-2766	224	17	brown	brown	PROPN
admet-2766	224	18	,	,	PUNCT
admet-2766	224	19	e.l	e.l	PROPN
admet-2766	224	20	.	.	PROPN
admet-2766	224	21	raven	raven	PROPN
admet-2766	224	22	,	,	PUNCT
admet-2766	224	23	p.c.e	p.c.e	NOUN
admet-2766	224	24	.	.	PROPN
admet-2766	224	25	moody	moody	PROPN
admet-2766	224	26	.	.	PUNCT
admet-2766	225	1	the	the	DET
admet-2766	225	2	tuberculosis	tuberculosis	NOUN
admet-2766	225	3	prodrug	prodrug	NOUN
admet-2766	225	4	isoniazid	isoniazid	NOUN
admet-2766	225	5	bound	bind	VERB
admet-2766	225	6	to	to	ADP
admet-2766	225	7	activating	activate	VERB
admet-2766	225	8	peroxidases	peroxidase	NOUN
admet-2766	225	9	.	.	PUNCT
admet-2766	226	1	journal	journal	NOUN
admet-2766	226	2	of	of	ADP
admet-2766	226	3	biological	biological	ADJ
admet-2766	226	4	chemistry	chemistry	NOUN
admet-2766	226	5	283	283	NUM
admet-2766	226	6	(	(	PUNCT
admet-2766	226	7	2008	2008	NUM
admet-2766	226	8	)	)	PUNCT
admet-2766	226	9	61936200	61936200	NUM
admet-2766	226	10	.	.	PUNCT
admet-2766	227	1	https://doi.org/10.1074/jbc.m707412200	https://doi.org/10.1074/jbc.m707412200	X
admet-2766	228	1	[	[	X
admet-2766	228	2	11	11	NUM
admet-2766	228	3	]	]	PUNCT
admet-2766	228	4	p.	p.	NOUN
admet-2766	228	5	purkan	purkan	PROPN
admet-2766	228	6	,	,	PUNCT
admet-2766	228	7	i.	i.	PROPN
admet-2766	228	8	ihsanawati	ihsanawati	PROPN
admet-2766	228	9	,	,	PUNCT
admet-2766	228	10	d.	d.	PROPN
admet-2766	228	11	natalia	natalia	PROPN
admet-2766	228	12	,	,	PUNCT
admet-2766	228	13	y.m	y.m	PROPN
admet-2766	228	14	.	.	PROPN
admet-2766	228	15	syah	syah	PROPN
admet-2766	228	16	,	,	PUNCT
admet-2766	228	17	d.s	d.s	PROPN
admet-2766	228	18	.	.	PROPN
admet-2766	228	19	retnoningrum	retnoningrum	PROPN
admet-2766	228	20	,	,	PUNCT
admet-2766	228	21	i.	i.	NOUN
admet-2766	228	22	siswanto	siswanto	PROPN
admet-2766	228	23	.	.	PUNCT
admet-2766	229	1	molecular	molecular	ADJ
admet-2766	229	2	analysis	analysis	NOUN
admet-2766	229	3	of	of	ADP
admet-2766	229	4	katg	katg	PROPN
admet-2766	229	5	encoding	encode	VERB
admet-2766	229	6	catalase	catalase	NOUN
admet-2766	229	7	-	-	PUNCT
admet-2766	229	8	peroxidase	peroxidase	NOUN
admet-2766	229	9	from	from	ADP
admet-2766	229	10	clinical	clinical	ADJ
admet-2766	229	11	isolate	isolate	NOUN
admet-2766	229	12	of	of	ADP
admet-2766	229	13	isoniazid	isoniazid	NOUN
admet-2766	229	14	-	-	PUNCT
admet-2766	229	15	resistant	resistant	ADJ
admet-2766	229	16	mycobacterium	mycobacterium	NOUN
admet-2766	229	17	tuberculosis	tuberculosis	NOUN
admet-2766	229	18	.	.	PUNCT
admet-2766	230	1	journal	journal	NOUN
admet-2766	230	2	of	of	ADP
admet-2766	230	3	medicine	medicine	NOUN
admet-2766	230	4	and	and	CCONJ
admet-2766	230	5	life	life	NOUN
admet-2766	230	6	11	11	NUM
admet-2766	230	7	(	(	PUNCT
admet-2766	230	8	2018	2018	NUM
admet-2766	230	9	)	)	PUNCT
admet-2766	230	10	160	160	NUM
admet-2766	230	11	-	-	SYM
admet-2766	230	12	167	167	NUM
admet-2766	230	13	.	.	PUNCT
admet-2766	231	1	https://pmc.ncbi.nlm.nih.gov/articles/pmc6101688/	https://pmc.ncbi.nlm.nih.gov/articles/pmc6101688/	PRON
admet-2766	232	1	[	[	X
admet-2766	232	2	12	12	NUM
admet-2766	232	3	]	]	X
admet-2766	232	4	w.j	w.j	PROPN
admet-2766	232	5	.	.	PROPN
admet-2766	232	6	koh	koh	PROPN
admet-2766	232	7	,	,	PUNCT
admet-2766	232	8	y.	y.	PROPN
admet-2766	232	9	ko	ko	PROPN
admet-2766	232	10	,	,	PUNCT
admet-2766	232	11	c.k	c.k	PROPN
admet-2766	232	12	.	.	PUNCT
admet-2766	232	13	kim	kim	PROPN
admet-2766	232	14	,	,	PUNCT
admet-2766	232	15	k.s	k.s	PROPN
admet-2766	232	16	.	.	PROPN
admet-2766	232	17	park	park	PROPN
admet-2766	232	18	,	,	PUNCT
admet-2766	232	19	n.y	n.y	PROPN
admet-2766	232	20	.	.	PROPN
admet-2766	232	21	lee	lee	PROPN
admet-2766	232	22	.	.	PROPN
admet-2766	233	1	rapid	rapid	ADJ
admet-2766	233	2	diagnosis	diagnosis	NOUN
admet-2766	233	3	of	of	ADP
admet-2766	233	4	tuberculosis	tuberculosis	NOUN
admet-2766	233	5	and	and	CCONJ
admet-2766	233	6	multidrug	multidrug	VERB
admet-2766	233	7	resistantce	resistantce	NOUN
admet-2766	233	8	using	use	VERB
admet-2766	233	9	a	a	DET
admet-2766	233	10	mgit	mgit	ADJ
admet-2766	233	11	960	960	NUM
admet-2766	233	12	system	system	NOUN
admet-2766	233	13	.	.	PUNCT
admet-2766	234	1	annals	annal	NOUN
admet-2766	234	2	of	of	ADP
admet-2766	234	3	laboratory	laboratory	NOUN
admet-2766	234	4	medicine	medicine	NOUN
admet-2766	234	5	32	32	NUM
admet-2766	234	6	(	(	PUNCT
admet-2766	234	7	2012	2012	NUM
admet-2766	234	8	)	)	PUNCT
admet-2766	234	9	264	264	NUM
admet-2766	234	10	-	-	SYM
admet-2766	234	11	269	269	NUM
admet-2766	234	12	.	.	PUNCT
admet-2766	235	1	http://dx.doi.org/10.3343/alm.2012.32.4.264	http://dx.doi.org/10.3343/alm.2012.32.4.264	PROPN
admet-2766	236	1	[	[	X
admet-2766	236	2	13	13	NUM
admet-2766	236	3	]	]	X
admet-2766	236	4	a.h	a.h	PROPN
admet-2766	236	5	.	.	PROPN
admet-2766	236	6	salim	salim	PROPN
admet-2766	236	7	,	,	PUNCT
admet-2766	236	8	k.j.m	k.j.m	ADJ
admet-2766	236	9	aung	aung	PROPN
admet-2766	236	10	,	,	PUNCT
admet-2766	236	11	m.a	m.a	PROPN
admet-2766	236	12	hossain	hossain	PROPN
admet-2766	236	13	,	,	PUNCT
admet-2766	236	14	a.v	a.v	PROPN
admet-2766	236	15	.	.	PROPN
admet-2766	236	16	deun	deun	NOUN
admet-2766	236	17	.	.	PUNCT
admet-2766	237	1	early	early	ADJ
admet-2766	237	2	and	and	CCONJ
admet-2766	237	3	rapid	rapid	ADJ
admet-2766	237	4	microscopy	microscopy	NOUN
admet-2766	237	5	-	-	PUNCT
admet-2766	237	6	based	base	VERB
admet-2766	237	7	diagnosis	diagnosis	NOUN
admet-2766	237	8	of	of	ADP
admet-2766	237	9	true	true	ADJ
admet-2766	237	10	treatment	treatment	NOUN
admet-2766	237	11	failure	failure	NOUN
admet-2766	237	12	and	and	CCONJ
admet-2766	237	13	mdr	mdr	PROPN
admet-2766	237	14	-	-	PROPN
admet-2766	237	15	tb	tb	PROPN
admet-2766	237	16	.	.	PUNCT
admet-2766	238	1	the	the	DET
admet-2766	238	2	international	international	ADJ
admet-2766	238	3	journal	journal	NOUN
admet-2766	238	4	of	of	ADP
admet-2766	238	5	tuberculosis	tuberculosis	NOUN
admet-2766	238	6	and	and	CCONJ
admet-2766	238	7	lung	lung	NOUN
admet-2766	238	8	disease	disease	NOUN
admet-2766	238	9	10	10	NUM
admet-2766	238	10	(	(	PUNCT
admet-2766	238	11	2006	2006	NUM
admet-2766	238	12	)	)	PUNCT
admet-2766	238	13	1248	1248	NUM
admet-2766	238	14	-	-	SYM
admet-2766	238	15	1254	1254	NUM
admet-2766	238	16	.	.	PUNCT
admet-2766	239	1	https://pubmed.ncbi.nlm.nih.gov/17131784/	https://pubmed.ncbi.nlm.nih.gov/17131784/	PROPN
admet-2766	239	2	[	[	X
admet-2766	239	3	14	14	NUM
admet-2766	239	4	]	]	X
admet-2766	239	5	c.c	c.c	PROPN
admet-2766	239	6	.	.	PROPN
admet-2766	239	7	boehme	boehme	PROPN
admet-2766	239	8	,	,	PUNCT
admet-2766	239	9	p.	p.	PROPN
admet-2766	239	10	nabeta	nabeta	PROPN
admet-2766	239	11	,	,	PUNCT
admet-2766	239	12	d.	d.	PROPN
admet-2766	239	13	hillemann	hillemann	PROPN
admet-2766	239	14	,	,	PUNCT
admet-2766	239	15	m.p	m.p	PROPN
admet-2766	239	16	.	.	PROPN
admet-2766	239	17	nicol	nicol	PROPN
admet-2766	239	18	,	,	PUNCT
admet-2766	239	19	s.	s.	PROPN
admet-2766	239	20	shenai	shenai	PROPN
admet-2766	239	21	,	,	PUNCT
admet-2766	239	22	f	f	PROPN
admet-2766	239	23	,	,	PUNCT
admet-2766	239	24	krapp	krapp	PROPN
admet-2766	239	25	,	,	PUNCT
admet-2766	239	26	j.	j.	PROPN
admet-2766	239	27	allen	allen	PROPN
admet-2766	239	28	,	,	PUNCT
admet-2766	239	29	r.	r.	PROPN
admet-2766	239	30	tahirli	tahirli	PROPN
admet-2766	239	31	,	,	PUNCT
admet-2766	239	32	r.	r.	PROPN
admet-2766	239	33	blakemore	blakemore	PROPN
admet-2766	239	34	,	,	PUNCT
admet-2766	239	35	r.	r.	PROPN
admet-2766	239	36	rustomjee	rustomjee	PROPN
admet-2766	239	37	,	,	PUNCT
admet-2766	239	38	a.	a.	NOUN
admet-2766	239	39	milovic	milovic	PROPN
admet-2766	239	40	,	,	PUNCT
admet-2766	239	41	m.	m.	NOUN
admet-2766	239	42	jones	jones	PROPN
admet-2766	239	43	,	,	PUNCT
admet-2766	239	44	s.	s.	PROPN
admet-2766	239	45	m.	m.	PROPN
admet-2766	239	46	o’brien	o’brien	PROPN
admet-2766	239	47	,	,	PUNCT
admet-2766	239	48	d.h	d.h	PROPN
admet-2766	239	49	.	.	PROPN
admet-2766	239	50	persing	persing	PROPN
admet-2766	239	51	,	,	PUNCT
admet-2766	239	52	s.	s.	PROPN
admet-2766	239	53	ruesch	ruesch	PROPN
admet-2766	239	54	-	-	PUNCT
admet-2766	239	55	gerdes	gerdes	PROPN
admet-2766	239	56	,	,	PUNCT
admet-2766	239	57	e.	e.	PROPN
admet-2766	239	58	gotuzzo	gotuzzo	PROPN
admet-2766	239	59	,	,	PUNCT
admet-2766	239	60	c.	c.	PROPN
admet-2766	239	61	rodrigues	rodrigues	PROPN
admet-2766	239	62	,	,	PUNCT
admet-2766	239	63	d.	d.	PROPN
admet-2766	239	64	alland	alland	PROPN
admet-2766	239	65	,	,	PUNCT
admet-2766	239	66	m.d	m.d	PROPN
admet-2766	239	67	.	.	PROPN
admet-2766	239	68	perkins	perkins	PROPN
admet-2766	239	69	.	.	PUNCT
admet-2766	240	1	rapid	rapid	ADJ
admet-2766	240	2	molecular	molecular	ADJ
admet-2766	240	3	detection	detection	NOUN
admet-2766	240	4	of	of	ADP
admet-2766	240	5	tuberculosis	tuberculosis	NOUN
admet-2766	240	6	and	and	CCONJ
admet-2766	240	7	rifampicin	rifampicin	VERB
admet-2766	240	8	resistant	resistant	ADJ
admet-2766	240	9	.	.	PUNCT
admet-2766	241	1	the	the	DET
admet-2766	241	2	new	new	PROPN
admet-2766	241	3	england	england	PROPN
admet-2766	241	4	journal	journal	PROPN
admet-2766	241	5	of	of	ADP
admet-2766	241	6	medicine	medicine	NOUN
admet-2766	241	7	363	363	NUM
admet-2766	241	8	(	(	PUNCT
admet-2766	241	9	2010	2010	NUM
admet-2766	241	10	)	)	PUNCT
admet-2766	241	11	1005	1005	NUM
admet-2766	241	12	-	-	SYM
admet-2766	241	13	1015	1015	NUM
admet-2766	241	14	.	.	PUNCT
admet-2766	242	1	https://doi.org/10.1056/nejmoa0907847	https://doi.org/10.1056/nejmoa0907847	PROPN
admet-2766	243	1	[	[	X
admet-2766	243	2	15	15	NUM
admet-2766	243	3	]	]	X
admet-2766	243	4	j.e	j.e	PROPN
admet-2766	243	5	.	.	PROPN
admet-2766	243	6	van	van	PROPN
admet-2766	243	7	dongen	dongen	PROPN
admet-2766	243	8	,	,	PUNCT
admet-2766	243	9	j.t.w	j.t.w	PROPN
admet-2766	243	10	.	.	PROPN
admet-2766	243	11	berendsen	berendsen	PROPN
admet-2766	243	12	,	,	PUNCT
admet-2766	243	13	r.d.m	r.d.m	PROPN
admet-2766	243	14	.	.	PUNCT
admet-2766	243	15	steenbergen	steenbergen	PROPN
admet-2766	243	16	,	,	PUNCT
admet-2766	243	17	r.m.f	r.m.f	ADJ
admet-2766	243	18	.	.	PUNCT
admet-2766	243	19	wolthuis	wolthuis	PROPN
admet-2766	243	20	,	,	PUNCT
admet-2766	243	21	j.c.t	j.c.t	PROPN
admet-2766	243	22	.	.	PUNCT
admet-2766	243	23	eijkel	eijkel	PROPN
admet-2766	243	24	,	,	PUNCT
admet-2766	243	25	l.i	l.i	PROPN
admet-2766	243	26	.	.	PROPN
admet-2766	243	27	segerink	segerink	PROPN
admet-2766	243	28	.	.	PUNCT
admet-2766	244	1	point	point	NOUN
admet-2766	244	2	-	-	PUNCT
admet-2766	244	3	of	of	ADP
admet-2766	244	4	-	-	PUNCT
admet-2766	244	5	care	care	NOUN
admet-2766	244	6	crispr	crispr	PROPN
admet-2766	244	7	/	/	SYM
admet-2766	244	8	cas	cas	PROPN
admet-2766	244	9	nucleic	nucleic	ADJ
admet-2766	244	10	acid	acid	PROPN
admet-2766	244	11	detection	detection	NOUN
admet-2766	244	12	:	:	PUNCT
admet-2766	244	13	recent	recent	ADJ
admet-2766	244	14	advances	advance	NOUN
admet-2766	244	15	,	,	PUNCT
admet-2766	244	16	challenges	challenge	NOUN
admet-2766	244	17	and	and	CCONJ
admet-2766	244	18	opportunities	opportunity	NOUN
admet-2766	244	19	.	.	PUNCT
admet-2766	245	1	biosensors	biosensor	NOUN
admet-2766	245	2	and	and	CCONJ
admet-2766	245	3	bioelectronics	bioelectronic	NOUN
admet-2766	245	4	166	166	NUM
admet-2766	245	5	(	(	PUNCT
admet-2766	245	6	2020	2020	NUM
admet-2766	245	7	)	)	PUNCT
admet-2766	245	8	112445	112445	NUM
admet-2766	245	9	.	.	PUNCT
admet-2766	246	1	https://doi.org/10.1016/j.bios.2020.112445	https://doi.org/10.1016/j.bios.2020.112445	NOUN
admet-2766	247	1	[	[	X
admet-2766	247	2	16	16	NUM
admet-2766	247	3	]	]	PUNCT
admet-2766	247	4	m.	m.	NOUN
admet-2766	247	5	wang	wang	PROPN
admet-2766	247	6	,	,	PUNCT
admet-2766	247	7	r.	r.	PROPN
admet-2766	247	8	zhang	zhang	PROPN
admet-2766	247	9	,	,	PUNCT
admet-2766	247	10	j.	j.	PROPN
admet-2766	247	11	li	li	PROPN
admet-2766	247	12	.	.	PROPN
admet-2766	247	13	crispr	crispr	PROPN
admet-2766	247	14	/	/	SYM
admet-2766	247	15	cas	cas	NOUN
admet-2766	247	16	system	system	NOUN
admet-2766	247	17	redefine	redefine	VERB
admet-2766	247	18	nucleic	nucleic	ADJ
admet-2766	247	19	acid	acid	NOUN
admet-2766	247	20	detection	detection	NOUN
admet-2766	247	21	:	:	PUNCT
admet-2766	247	22	principles	principle	NOUN
admet-2766	247	23	and	and	CCONJ
admet-2766	247	24	methods	method	NOUN
admet-2766	247	25	.	.	PUNCT
admet-2766	248	1	biosensors	biosensor	NOUN
admet-2766	248	2	and	and	CCONJ
admet-2766	248	3	bioelectronics	bioelectronic	NOUN
admet-2766	248	4	165	165	NUM
admet-2766	248	5	(	(	PUNCT
admet-2766	248	6	2020	2020	NUM
admet-2766	248	7	)	)	PUNCT
admet-2766	248	8	112430	112430	NUM
admet-2766	248	9	.	.	PUNCT
admet-2766	249	1	https://doi.org/10.1016/j.bios.2020.112430	https://doi.org/10.1016/j.bios.2020.112430	PROPN
admet-2766	249	2	[	[	X
admet-2766	249	3	17	17	NUM
admet-2766	249	4	]	]	X
admet-2766	249	5	m.i.h.l	m.i.h.l	PROPN
admet-2766	249	6	.	.	PROPN
admet-2766	249	7	zein	zein	PROPN
admet-2766	249	8	,	,	PUNCT
admet-2766	249	9	a.	a.	PROPN
admet-2766	249	10	hardianto	hardianto	PROPN
admet-2766	249	11	,	,	PUNCT
admet-2766	249	12	irkham	irkham	PROPN
admet-2766	249	13	,	,	PUNCT
admet-2766	249	14	y.w	y.w	PROPN
admet-2766	249	15	.	.	PROPN
admet-2766	249	16	hartati	hartati	PROPN
admet-2766	249	17	,	,	PUNCT
admet-2766	249	18	identification	identification	NOUN
admet-2766	249	19	of	of	ADP
admet-2766	249	20	crispr	crispr	ADJ
admet-2766	249	21	/	/	SYM
admet-2766	249	22	cas12a	cas12a	ADJ
admet-2766	249	23	(	(	PUNCT
admet-2766	249	24	cpf1	cpf1	NOUN
admet-2766	249	25	)	)	PUNCT
admet-2766	249	26	guiderna	guiderna	NOUN
admet-2766	249	27	sequence	sequence	NOUN
admet-2766	249	28	targeting	target	VERB
admet-2766	249	29	the	the	DET
admet-2766	249	30	mitochondrial	mitochondrial	ADJ
admet-2766	249	31	dna	dna	NOUN
admet-2766	249	32	d	d	NOUN
admet-2766	249	33	-	-	PUNCT
admet-2766	249	34	loop	loop	NOUN
admet-2766	249	35	region	region	NOUN
admet-2766	249	36	in	in	ADP
admet-2766	249	37	wild	wild	ADJ
admet-2766	249	38	pig	pig	NOUN
admet-2766	249	39	(	(	PUNCT
admet-2766	249	40	sus	sus	PROPN
admet-2766	249	41	scrofa	scrofa	NOUN
admet-2766	249	42	)	)	PUNCT
admet-2766	249	43	through	through	ADP
admet-2766	249	44	homology	homology	NOUN
admet-2766	249	45	difference	difference	NOUN
admet-2766	249	46	and	and	CCONJ
admet-2766	249	47	mismatch	mismatch	ADJ
admet-2766	249	48	analysis	analysis	NOUN
admet-2766	249	49	.	.	PUNCT
admet-2766	250	1	trends	trend	NOUN
admet-2766	250	2	in	in	ADP
admet-2766	250	3	sciences	science	NOUN
admet-2766	250	4	21	21	NUM
admet-2766	250	5	(	(	PUNCT
admet-2766	250	6	2024	2024	NUM
admet-2766	250	7	)	)	PUNCT
admet-2766	250	8	7603	7603	NUM
admet-2766	250	9	.	.	PUNCT
admet-2766	251	1	https://doi.org/10.48048/tis.2024.7603	https://doi.org/10.48048/tis.2024.7603	NOUN
admet-2766	252	1	[	[	X
admet-2766	252	2	18	18	NUM
admet-2766	252	3	]	]	X
admet-2766	252	4	v.	v.	PROPN
admet-2766	252	5	konstantakos	konstantakos	PROPN
admet-2766	252	6	,	,	PUNCT
admet-2766	252	7	a.	a.	PROPN
admet-2766	252	8	nentidis	nentidis	PROPN
admet-2766	252	9	,	,	PUNCT
admet-2766	252	10	a.	a.	NOUN
admet-2766	252	11	krithara	krithara	PROPN
admet-2766	252	12	,	,	PUNCT
admet-2766	252	13	g.	g.	PROPN
admet-2766	252	14	paliouras	paliouras	PROPN
admet-2766	252	15	,	,	PUNCT
admet-2766	252	16	crispr	crispr	ADJ
admet-2766	252	17	-	-	PUNCT
admet-2766	252	18	cas9	cas9	NOUN
admet-2766	252	19	grna	grna	NOUN
admet-2766	252	20	efficiency	efficiency	NOUN
admet-2766	252	21	prediction	prediction	NOUN
admet-2766	252	22	:	:	PUNCT
admet-2766	252	23	an	an	DET
admet-2766	252	24	overview	overview	NOUN
admet-2766	252	25	of	of	ADP
admet-2766	252	26	predictive	predictive	ADJ
admet-2766	252	27	tools	tool	NOUN
admet-2766	252	28	and	and	CCONJ
admet-2766	252	29	the	the	DET
admet-2766	252	30	role	role	NOUN
admet-2766	252	31	of	of	ADP
admet-2766	252	32	deep	deep	ADJ
admet-2766	252	33	learning	learning	NOUN
admet-2766	252	34	,	,	PUNCT
admet-2766	252	35	nucleic	nucleic	ADJ
admet-2766	252	36	acids	acid	NOUN
admet-2766	252	37	research	research	NOUN
admet-2766	252	38	50	50	NUM
admet-2766	252	39	(	(	PUNCT
admet-2766	252	40	2022	2022	NUM
admet-2766	252	41	)	)	PUNCT
admet-2766	252	42	36163637	36163637	NUM
admet-2766	252	43	.	.	PUNCT
admet-2766	253	1	https://doi.org/10.1093/nar/gkac192	https://doi.org/10.1093/nar/gkac192	PRON
admet-2766	254	1	[	[	X
admet-2766	254	2	19	19	NUM
admet-2766	254	3	]	]	X
admet-2766	254	4	s.n	s.n	PROPN
admet-2766	254	5	.	.	PROPN
admet-2766	254	6	zakiyyah	zakiyyah	PROPN
admet-2766	254	7	,	,	PUNCT
admet-2766	254	8	a.u	a.u	PROPN
admet-2766	254	9	.	.	PROPN
admet-2766	254	10	ibrahim	ibrahim	PROPN
admet-2766	254	11	,	,	PUNCT
admet-2766	254	12	m.s	m.s	PROPN
admet-2766	254	13	.	.	PROPN
admet-2766	254	14	babiker	babiker	PROPN
admet-2766	254	15	,	,	PUNCT
admet-2766	254	16	s.	s.	PROPN
admet-2766	254	17	gaffer	gaffer	PROPN
admet-2766	254	18	,	,	PUNCT
admet-2766	254	19	m.	m.	NOUN
admet-2766	254	20	ozsoz	ozsoz	PROPN
admet-2766	254	21	,	,	PUNCT
admet-2766	254	22	m.i.h.l	m.i.h.l	PROPN
admet-2766	254	23	.	.	PROPN
admet-2766	254	24	zein	zein	PROPN
admet-2766	254	25	,	,	PUNCT
admet-2766	254	26	y.w	y.w	PROPN
admet-2766	254	27	.	.	PROPN
admet-2766	254	28	hartati	hartati	PROPN
admet-2766	254	29	.	.	PUNCT
admet-2766	255	1	detection	detection	NOUN
admet-2766	255	2	of	of	ADP
admet-2766	255	3	tropical	tropical	ADJ
admet-2766	255	4	diseases	disease	NOUN
admet-2766	255	5	caused	cause	VERB
admet-2766	255	6	by	by	ADP
admet-2766	255	7	mosquitoes	mosquito	NOUN
admet-2766	255	8	using	use	VERB
admet-2766	255	9	crispr	crispr	NOUN
admet-2766	255	10	-	-	PUNCT
admet-2766	255	11	based	base	VERB
admet-2766	255	12	biosensors	biosensor	NOUN
admet-2766	255	13	.	.	PUNCT
admet-2766	256	1	tropical	tropical	ADJ
admet-2766	256	2	medicine	medicine	NOUN
admet-2766	256	3	and	and	CCONJ
admet-2766	256	4	infectious	infectious	ADJ
admet-2766	256	5	disease	disease	NOUN
admet-2766	256	6	7	7	NUM
admet-2766	256	7	(	(	PUNCT
admet-2766	256	8	2022	2022	NUM
admet-2766	256	9	)	)	PUNCT
admet-2766	256	10	309	309	NUM
admet-2766	256	11	.	.	PUNCT
admet-2766	257	1	https://doi.org/10.3390/tropicalmed7100309	https://doi.org/10.3390/tropicalmed7100309	PROPN
admet-2766	258	1	[	[	X
admet-2766	258	2	20	20	NUM
admet-2766	258	3	]	]	SYM
admet-2766	258	4	irkham	irkham	NOUN
admet-2766	258	5	,	,	PUNCT
admet-2766	258	6	a.u	a.u	PROPN
admet-2766	258	7	.	.	PROPN
admet-2766	258	8	ibrahim	ibrahim	PROPN
admet-2766	258	9	,	,	PUNCT
admet-2766	258	10	p.c	p.c	PROPN
admet-2766	258	11	.	.	PROPN
admet-2766	258	12	pwavodi	pwavodi	PROPN
admet-2766	258	13	,	,	PUNCT
admet-2766	258	14	c.w	c.w	PROPN
admet-2766	258	15	.	.	PROPN
admet-2766	258	16	nwekwo	nwekwo	PROPN
admet-2766	258	17	,	,	PUNCT
admet-2766	258	18	y.w	y.w	PROPN
admet-2766	258	19	.	.	PROPN
admet-2766	258	20	hartati	hartati	PROPN
admet-2766	258	21	.	.	PUNCT
admet-2766	259	1	crispr	crispr	NOUN
admet-2766	259	2	-	-	PUNCT
admet-2766	259	3	based	base	VERB
admet-2766	259	4	biosensor	biosensor	NOUN
admet-2766	259	5	for	for	ADP
admet-2766	259	6	the	the	DET
admet-2766	259	7	detection	detection	NOUN
admet-2766	259	8	of	of	ADP
admet-2766	259	9	marburg	marburg	PROPN
admet-2766	259	10	and	and	CCONJ
admet-2766	259	11	ebola	ebola	PROPN
admet-2766	259	12	virus	virus	NOUN
admet-2766	259	13	.	.	PUNCT
admet-2766	260	1	sensing	sense	VERB
admet-2766	260	2	and	and	CCONJ
admet-2766	260	3	bio	bio	ADV
admet-2766	260	4	-	-	ADJ
admet-2766	260	5	sensing	sensing	ADJ
admet-2766	260	6	research	research	NOUN
admet-2766	260	7	43	43	NUM
admet-2766	260	8	(	(	PUNCT
admet-2766	260	9	2024	2024	NUM
admet-2766	260	10	)	)	PUNCT
admet-2766	260	11	100641	100641	NUM
admet-2766	260	12	.	.	PUNCT
admet-2766	261	1	https://doi.org/10.1016/j.sbsr.2023.100601	https://doi.org/10.1016/j.sbsr.2023.100601	PROPN
admet-2766	261	2	[	[	X
admet-2766	261	3	21	21	NUM
admet-2766	261	4	]	]	X
admet-2766	261	5	irkham	irkham	NOUN
admet-2766	261	6	,	,	PUNCT
admet-2766	261	7	a.u	a.u	PROPN
admet-2766	261	8	.	.	PROPN
admet-2766	261	9	ibrahim	ibrahim	PROPN
admet-2766	261	10	,	,	PUNCT
admet-2766	261	11	c.w	c.w	PROPN
admet-2766	261	12	.	.	PROPN
admet-2766	261	13	nwekwo	nwekwo	PROPN
admet-2766	261	14	,	,	PUNCT
admet-2766	261	15	p.c	p.c	PROPN
admet-2766	261	16	.	.	PROPN
admet-2766	261	17	pwavodi	pwavodi	PROPN
admet-2766	261	18	,	,	PUNCT
admet-2766	261	19	s.n	s.n	PROPN
admet-2766	261	20	.	.	PROPN
admet-2766	261	21	zakiyyah	zakiyyah	PROPN
admet-2766	261	22	,	,	PUNCT
admet-2766	261	23	m.	m.	NOUN
admet-2766	261	24	ozsoz	ozsoz	PROPN
admet-2766	261	25	,	,	PUNCT
admet-2766	261	26	y.w	y.w	PROPN
admet-2766	261	27	.	.	PROPN
admet-2766	261	28	hartati	hartati	PROPN
admet-2766	261	29	.	.	PUNCT
admet-2766	262	1	from	from	ADP
admet-2766	262	2	nanotechnology	nanotechnology	PROPN
admet-2766	262	3	to	to	PART
admet-2766	262	4	ai	ai	VERB
admet-2766	262	5	:	:	PUNCT
admet-2766	262	6	the	the	DET
admet-2766	262	7	next	next	ADJ
admet-2766	262	8	generation	generation	NOUN
admet-2766	262	9	of	of	ADP
admet-2766	262	10	crispr	crispr	NOUN
admet-2766	262	11	-	-	PUNCT
admet-2766	262	12	based	base	VERB
admet-2766	262	13	smart	smart	ADJ
admet-2766	262	14	biosensors	biosensor	NOUN
admet-2766	262	15	for	for	ADP
admet-2766	262	16	infectious	infectious	ADJ
admet-2766	262	17	disease	disease	NOUN
admet-2766	262	18	detection	detection	NOUN
admet-2766	262	19	.	.	PUNCT
admet-2766	263	1	microchemical	microchemical	ADJ
admet-2766	263	2	journal	journal	PROPN
admet-2766	263	3	208	208	NUM
admet-2766	263	4	(	(	PUNCT
admet-2766	263	5	2025	2025	NUM
admet-2766	263	6	)	)	PUNCT
admet-2766	263	7	112577	112577	NUM
admet-2766	263	8	.	.	PUNCT
admet-2766	264	1	https://doi.org/10.1016/j.microc.2024.112577	https://doi.org/10.1016/j.microc.2024.112577	PROPN
admet-2766	264	2	[	[	X
admet-2766	264	3	22	22	NUM
admet-2766	264	4	]	]	X
admet-2766	264	5	g.i	g.i	PROPN
admet-2766	264	6	.	.	PROPN
admet-2766	264	7	corsi	corsi	PROPN
admet-2766	264	8	,	,	PUNCT
admet-2766	264	9	k.	k.	PROPN
admet-2766	264	10	qu	qu	PROPN
admet-2766	264	11	,	,	PUNCT
admet-2766	264	12	f.	f.	PROPN
admet-2766	264	13	alkan	alkan	PROPN
admet-2766	264	14	,	,	PUNCT
admet-2766	264	15	x.	x.	PROPN
admet-2766	264	16	pan	pan	PROPN
admet-2766	264	17	,	,	PUNCT
admet-2766	264	18	y.	y.	PROPN
admet-2766	264	19	luo	luo	PROPN
admet-2766	264	20	,	,	PUNCT
admet-2766	265	1	j.	j.	PROPN
admet-2766	265	2	gorodkin	gorodkin	PROPN
admet-2766	265	3	.	.	PUNCT
admet-2766	265	4	crispr	crispr	PROPN
admet-2766	265	5	/	/	SYM
admet-2766	265	6	cas9	cas9	NOUN
admet-2766	265	7	grna	grna	NOUN
admet-2766	265	8	activity	activity	NOUN
admet-2766	265	9	depends	depend	VERB
admet-2766	265	10	on	on	ADP
admet-2766	265	11	free	free	ADJ
admet-2766	265	12	energy	energy	NOUN
admet-2766	265	13	changes	change	NOUN
admet-2766	265	14	and	and	CCONJ
admet-2766	265	15	on	on	ADP
admet-2766	265	16	the	the	DET
admet-2766	265	17	target	target	NOUN
admet-2766	265	18	pam	pam	NOUN
admet-2766	265	19	context	context	NOUN
admet-2766	265	20	.	.	PUNCT
admet-2766	266	1	nature	nature	NOUN
admet-2766	266	2	communication	communication	NOUN
admet-2766	266	3	13	13	NUM
admet-2766	266	4	(	(	PUNCT
admet-2766	266	5	2022	2022	NUM
admet-2766	266	6	)	)	PUNCT
admet-2766	266	7	3006	3006	NUM
admet-2766	266	8	.	.	PUNCT
admet-2766	267	1	https://doi.org/10.1038/s41467-022-30515-0	https://doi.org/10.1038/s41467-022-30515-0	PUNCT
admet-2766	268	1	https://doi.org/10.1016/j.cimid.2020.101574	https://doi.org/10.1016/j.cimid.2020.101574	NOUN
admet-2766	268	2	https://doi.org/10.12701/yujm.2020.00626	https://doi.org/10.12701/yujm.2020.00626	PROPN
admet-2766	268	3	https://doi.org/10.1016/j.cmi.2020.07.004	https://doi.org/10.1016/j.cmi.2020.07.004	NOUN
admet-2766	268	4	https://doi.org/10.1074/jbc.m707412200	https://doi.org/10.1074/jbc.m707412200	X
admet-2766	269	1	https://pmc.ncbi.nlm.nih.gov/articles/pmc6101688/	https://pmc.ncbi.nlm.nih.gov/articles/pmc6101688/	PROPN
admet-2766	269	2	http://dx.doi.org/10.3343/alm.2012.32.4.264	http://dx.doi.org/10.3343/alm.2012.32.4.264	PROPN
admet-2766	269	3	https://pubmed.ncbi.nlm.nih.gov/17131784/	https://pubmed.ncbi.nlm.nih.gov/17131784/	PROPN
admet-2766	269	4	https://doi.org/10.1056/nejmoa0907847	https://doi.org/10.1056/nejmoa0907847	PROPN
admet-2766	269	5	https://doi.org/10.1016/j.bios.2020.112445	https://doi.org/10.1016/j.bios.2020.112445	PROPN
admet-2766	269	6	https://doi.org/10.1016/j.bios.2020.112430	https://doi.org/10.1016/j.bios.2020.112430	PROPN
admet-2766	269	7	https://doi.org/10.48048/tis.2024.7603	https://doi.org/10.48048/tis.2024.7603	NOUN
admet-2766	269	8	https://doi.org/10.1093/nar/gkac192	https://doi.org/10.1093/nar/gkac192	NOUN
admet-2766	269	9	https://doi.org/10.3390/tropicalmed7100309	https://doi.org/10.3390/tropicalmed7100309	NOUN
admet-2766	269	10	https://doi.org/10.1016/j.sbsr.2023.100601	https://doi.org/10.1016/j.sbsr.2023.100601	PROPN
admet-2766	269	11	https://doi.org/10.1016/j.microc.2024.112577	https://doi.org/10.1016/j.microc.2024.112577	PROPN
admet-2766	269	12	https://doi.org/10.1038/s41467-022-30515-0	https://doi.org/10.1038/s41467-022-30515-0	NUM
admet-2766	269	13	admet	admet	PROPN
admet-2766	269	14	&	&	CCONJ
admet-2766	269	15	dmpk	dmpk	PROPN
admet-2766	269	16	13(3	13(3	NUM
admet-2766	269	17	)	)	PUNCT
admet-2766	269	18	(	(	PUNCT
admet-2766	269	19	2025	2025	NUM
admet-2766	269	20	)	)	PUNCT
admet-2766	269	21	2766	2766	NUM
admet-2766	269	22	crispr	crispr	ADJ
admet-2766	269	23	/	/	SYM
admet-2766	269	24	cas9	cas9	NOUN
admet-2766	269	25	biosensor	biosensor	NOUN
admet-2766	269	26	for	for	ADP
admet-2766	269	27	the	the	DET
admet-2766	269	28	detection	detection	NOUN
admet-2766	269	29	of	of	ADP
admet-2766	269	30	katg	katg	PROPN
admet-2766	269	31	gene	gene	NOUN
admet-2766	269	32	mutations	mutation	NOUN
admet-2766	269	33	doi	doi	NOUN
admet-2766	269	34	:	:	PUNCT
admet-2766	269	35	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	269	36	13	13	NUM
admet-2766	269	37	[	[	X
admet-2766	269	38	23	23	NUM
admet-2766	269	39	]	]	PUNCT
admet-2766	269	40	f.j.m	f.j.m	NOUN
admet-2766	269	41	.	.	PUNCT
admet-2766	269	42	mojica	mojica	PROPN
admet-2766	269	43	,	,	PUNCT
admet-2766	269	44	c.	c.	PROPN
admet-2766	269	45	díez	díez	PROPN
admet-2766	269	46	-	-	PUNCT
admet-2766	269	47	villaseñor	villaseñor	PROPN
admet-2766	269	48	,	,	PUNCT
admet-2766	269	49	j.	j.	PROPN
admet-2766	269	50	garcía	garcía	PROPN
admet-2766	269	51	-	-	PUNCT
admet-2766	269	52	martínez	martínez	NOUN
admet-2766	269	53	,	,	PUNCT
admet-2766	269	54	c.	c.	PROPN
admet-2766	269	55	almendros	almendros	PROPN
admet-2766	269	56	.	.	PUNCT
admet-2766	270	1	short	short	ADJ
admet-2766	270	2	motif	motif	NOUN
admet-2766	270	3	sequences	sequence	NOUN
admet-2766	270	4	determine	determine	VERB
admet-2766	270	5	the	the	DET
admet-2766	270	6	targets	target	NOUN
admet-2766	270	7	of	of	ADP
admet-2766	270	8	the	the	DET
admet-2766	270	9	prokaryotic	prokaryotic	ADJ
admet-2766	270	10	crispr	crispr	ADJ
admet-2766	270	11	defence	defence	NOUN
admet-2766	270	12	system	system	NOUN
admet-2766	270	13	.	.	PUNCT
admet-2766	271	1	microbiology	microbiology	NOUN
admet-2766	271	2	155	155	NUM
admet-2766	271	3	(	(	PUNCT
admet-2766	271	4	2009	2009	NUM
admet-2766	271	5	)	)	PUNCT
admet-2766	271	6	733	733	NUM
admet-2766	271	7	-	-	SYM
admet-2766	271	8	740	740	NUM
admet-2766	271	9	.	.	PUNCT
admet-2766	272	1	https://doi.org/10.1099/mic.0.023960-0	https://doi.org/10.1099/mic.0.023960-0	NOUN
admet-2766	272	2	[	[	X
admet-2766	272	3	24	24	NUM
admet-2766	272	4	]	]	X
admet-2766	272	5	n.	n.	PROPN
admet-2766	272	6	wong	wong	PROPN
admet-2766	272	7	,	,	PUNCT
admet-2766	272	8	w.	w.	PROPN
admet-2766	272	9	liu	liu	PROPN
admet-2766	272	10	,	,	PUNCT
admet-2766	272	11	x.	x.	PROPN
admet-2766	272	12	wang	wang	PROPN
admet-2766	272	13	.	.	PUNCT
admet-2766	273	1	wu	wu	PROPN
admet-2766	273	2	-	-	PUNCT
admet-2766	273	3	crispr	crispr	NOUN
admet-2766	273	4	:	:	PUNCT
admet-2766	273	5	characteristics	characteristic	NOUN
admet-2766	273	6	of	of	ADP
admet-2766	273	7	functional	functional	ADJ
admet-2766	273	8	guide	guide	NOUN
admet-2766	273	9	rnas	rna	NOUN
admet-2766	273	10	for	for	ADP
admet-2766	273	11	the	the	DET
admet-2766	273	12	crispr	crispr	ADJ
admet-2766	273	13	/	/	SYM
admet-2766	273	14	cas9	cas9	NOUN
admet-2766	273	15	system	system	NOUN
admet-2766	273	16	.	.	PUNCT
admet-2766	274	1	genome	genome	NOUN
admet-2766	274	2	biology	biology	NOUN
admet-2766	274	3	16	16	NUM
admet-2766	274	4	(	(	PUNCT
admet-2766	274	5	2015	2015	NUM
admet-2766	274	6	)	)	PUNCT
admet-2766	274	7	218	218	NUM
admet-2766	274	8	.	.	PUNCT
admet-2766	275	1	https://doi.org/10.1186/s13059-015-0784-0	https://doi.org/10.1186/s13059-015-0784-0	NUM
admet-2766	276	1	[	[	X
admet-2766	276	2	25	25	NUM
admet-2766	276	3	]	]	PUNCT
admet-2766	276	4	l.	l.	PROPN
admet-2766	276	5	augustin	augustin	PROPN
admet-2766	276	6	,	,	PUNCT
admet-2766	276	7	n.	n.	PROPN
admet-2766	276	8	agarwal	agarwal	PROPN
admet-2766	276	9	.	.	PUNCT
admet-2766	277	1	designing	design	VERB
admet-2766	277	2	a	a	DET
admet-2766	277	3	cas9	cas9	NOUN
admet-2766	277	4	/	/	SYM
admet-2766	277	5	grna	grna	NOUN
admet-2766	277	6	-	-	PUNCT
admet-2766	277	7	assisted	assist	VERB
admet-2766	277	8	quantitative	quantitative	ADJ
admet-2766	277	9	real	real	ADJ
admet-2766	277	10	-	-	PUNCT
admet-2766	277	11	time	time	NOUN
admet-2766	277	12	pcr	pcr	NOUN
admet-2766	277	13	(	(	PUNCT
admet-2766	277	14	carp	carp	NOUN
admet-2766	277	15	)	)	PUNCT
admet-2766	277	16	assay	assay	VERB
admet-2766	277	17	for	for	ADP
admet-2766	277	18	identification	identification	NOUN
admet-2766	277	19	of	of	ADP
admet-2766	277	20	point	point	NOUN
admet-2766	277	21	mutations	mutation	NOUN
admet-2766	277	22	leading	lead	VERB
admet-2766	277	23	to	to	ADP
admet-2766	277	24	rifampicin	rifampicin	VERB
admet-2766	277	25	resistance	resistance	NOUN
admet-2766	277	26	in	in	ADP
admet-2766	277	27	the	the	DET
admet-2766	277	28	human	human	ADJ
admet-2766	277	29	pathogen	pathogen	NOUN
admet-2766	277	30	mycobacterium	mycobacterium	NOUN
admet-2766	277	31	tuberculosis	tuberculosis	NOUN
admet-2766	277	32	.	.	PUNCT
admet-2766	278	1	gene	gene	NOUN
admet-2766	278	2	857	857	NUM
admet-2766	278	3	(	(	PUNCT
admet-2766	278	4	2023	2023	NUM
admet-2766	278	5	)	)	PUNCT
admet-2766	278	6	147173	147173	NUM
admet-2766	278	7	.	.	PUNCT
admet-2766	279	1	https://doi.org/10.1016/j.gene.2023.147173	https://doi.org/10.1016/j.gene.2023.147173	NOUN
admet-2766	279	2	[	[	X
admet-2766	279	3	26	26	NUM
admet-2766	279	4	]	]	X
admet-2766	279	5	e.	e.	PROPN
admet-2766	279	6	kivrak	kivrak	PROPN
admet-2766	279	7	,	,	PUNCT
admet-2766	279	8	t.	t.	PROPN
admet-2766	279	9	pauzaite	pauzaite	PROPN
admet-2766	279	10	,	,	PUNCT
admet-2766	279	11	m.a	m.a	PROPN
admet-2766	279	12	.	.	PROPN
admet-2766	279	13	copeland	copeland	PROPN
admet-2766	279	14	,	,	PUNCT
admet-2766	279	15	j.g	j.g	PROPN
admet-2766	279	16	.	.	NOUN
admet-2766	279	17	hardy	hardy	ADJ
admet-2766	279	18	,	,	PUNCT
admet-2766	279	19	p.	p.	NOUN
admet-2766	279	20	kara	kara	PROPN
admet-2766	279	21	,	,	PUNCT
admet-2766	279	22	m.	m.	NOUN
admet-2766	279	23	firlak	firlak	PROPN
admet-2766	279	24	,	,	PUNCT
admet-2766	279	25	a.i	a.i	PROPN
admet-2766	279	26	.	.	PROPN
admet-2766	279	27	yardimci	yardimci	PROPN
admet-2766	279	28	,	,	PUNCT
admet-2766	279	29	s.	s.	PROPN
admet-2766	279	30	yilmaz	yilmaz	PROPN
admet-2766	279	31	,	,	PUNCT
admet-2766	279	32	f.	f.	PROPN
admet-2766	279	33	palaz	palaz	PROPN
admet-2766	279	34	,	,	PUNCT
admet-2766	279	35	m.	m.	NOUN
admet-2766	279	36	ozsoz	ozsoz	PROPN
admet-2766	279	37	.	.	PUNCT
admet-2766	280	1	detection	detection	NOUN
admet-2766	280	2	of	of	ADP
admet-2766	280	3	crispr	crispr	ADJ
admet-2766	280	4	-	-	PUNCT
admet-2766	280	5	cas9	cas9	NOUN
admet-2766	280	6	-	-	PUNCT
admet-2766	280	7	mediated	mediate	VERB
admet-2766	280	8	mutations	mutation	NOUN
admet-2766	280	9	using	use	VERB
admet-2766	280	10	a	a	DET
admet-2766	280	11	carbon	carbon	NOUN
admet-2766	280	12	nanotube	nanotube	NOUN
admet-2766	280	13	-	-	PUNCT
admet-2766	280	14	modified	modify	VERB
admet-2766	280	15	electrochemical	electrochemical	ADJ
admet-2766	280	16	genosensor	genosensor	NOUN
admet-2766	280	17	.	.	PUNCT
admet-2766	281	1	biosensors	biosensor	NOUN
admet-2766	281	2	11/1	11/1	NUM
admet-2766	281	3	)	)	PUNCT
admet-2766	281	4	(	(	PUNCT
admet-2766	281	5	2021	2021	NUM
admet-2766	281	6	)	)	PUNCT
admet-2766	281	7	17	17	NUM
admet-2766	281	8	.	.	PUNCT
admet-2766	282	1	https://doi.org/10.3390/bios11010017	https://doi.org/10.3390/bios11010017	X
admet-2766	282	2	.	.	PUNCT
admet-2766	283	1	[	[	X
admet-2766	283	2	27	27	NUM
admet-2766	283	3	]	]	X
admet-2766	283	4	m.i.h.l	m.i.h.l	PROPN
admet-2766	283	5	.	.	PROPN
admet-2766	283	6	zein	zein	PROPN
admet-2766	283	7	,	,	PUNCT
admet-2766	283	8	c.y	c.y	PROPN
admet-2766	283	9	.	.	PROPN
admet-2766	283	10	kharismasari	kharismasari	PROPN
admet-2766	283	11	,	,	PUNCT
admet-2766	283	12	a.	a.	PROPN
admet-2766	283	13	hardianto	hardianto	PROPN
admet-2766	283	14	,	,	PUNCT
admet-2766	283	15	s.n	s.n	PROPN
admet-2766	283	16	.	.	PROPN
admet-2766	283	17	zakiyyah	zakiyyah	PROPN
admet-2766	283	18	,	,	PUNCT
admet-2766	283	19	r.	r.	PROPN
admet-2766	283	20	amalia	amalia	PROPN
admet-2766	283	21	,	,	PUNCT
admet-2766	283	22	m.	m.	NOUN
admet-2766	283	23	ozsoz	ozsoz	PROPN
admet-2766	283	24	,	,	PUNCT
admet-2766	283	25	m.	m.	NOUN
admet-2766	283	26	mirasoli	mirasoli	ADJ
admet-2766	283	27	,	,	PUNCT
admet-2766	283	28	irkham	irkham	NOUN
admet-2766	283	29	,	,	PUNCT
admet-2766	283	30	y.w	y.w	PROPN
admet-2766	283	31	.	.	PROPN
admet-2766	283	32	hartati	hartati	PROPN
admet-2766	283	33	.	.	PUNCT
admet-2766	284	1	a	a	DET
admet-2766	284	2	crispr	crispr	ADJ
admet-2766	284	3	/	/	SYM
admet-2766	284	4	cas12a	cas12a	ADJ
admet-2766	284	5	electrochemical	electrochemical	ADJ
admet-2766	284	6	biosensing	biosensing	NOUN
admet-2766	284	7	to	to	PART
admet-2766	284	8	detect	detect	VERB
admet-2766	284	9	pig	pig	NOUN
admet-2766	284	10	mtdna	mtdna	NOUN
admet-2766	284	11	d	d	NOUN
admet-2766	284	12	-	-	PUNCT
admet-2766	284	13	loop	loop	NOUN
admet-2766	284	14	for	for	ADP
admet-2766	284	15	ensuring	ensure	VERB
admet-2766	284	16	food	food	NOUN
admet-2766	284	17	authenticity	authenticity	NOUN
admet-2766	284	18	.	.	PUNCT
admet-2766	285	1	sensing	sense	VERB
admet-2766	285	2	and	and	CCONJ
admet-2766	285	3	bio	bio	ADV
admet-2766	285	4	-	-	ADJ
admet-2766	285	5	sensing	sense	VERB
admet-2766	285	6	research	research	NOUN
admet-2766	285	7	47	47	NUM
admet-2766	285	8	(	(	PUNCT
admet-2766	285	9	2025	2025	NUM
admet-2766	285	10	)	)	PUNCT
admet-2766	285	11	100755	100755	NUM
admet-2766	285	12	.	.	PUNCT
admet-2766	286	1	https://doi.org/10.1016/j.sbsr.2025.100755	https://doi.org/10.1016/j.sbsr.2025.100755	ADJ
admet-2766	286	2	[	[	X
admet-2766	286	3	28	28	NUM
admet-2766	286	4	]	]	X
admet-2766	286	5	h.n	h.n	PROPN
admet-2766	286	6	.	.	PROPN
admet-2766	286	7	nguyen	nguyen	PROPN
admet-2766	286	8	,	,	PUNCT
admet-2766	286	9	,	,	PUNCT
admet-2766	286	10	s.	s.	PROPN
admet-2766	286	11	hwang	hwang	PROPN
admet-2766	286	12	,	,	PUNCT
admet-2766	286	13	s.w	s.w	PROPN
admet-2766	286	14	.	.	PROPN
admet-2766	286	15	lee	lee	PROPN
admet-2766	286	16	,	,	PUNCT
admet-2766	286	17	e.	e.	PROPN
admet-2766	286	18	jin	jin	PROPN
admet-2766	286	19	,	,	PUNCT
admet-2766	286	20	m.	m.	PROPN
admet-2766	286	21	lee	lee	PROPN
admet-2766	286	22	.	.	PROPN
admet-2766	287	1	detection	detection	NOUN
admet-2766	287	2	of	of	ADP
admet-2766	287	3	hpv	hpv	NOUN
admet-2766	287	4	16	16	NUM
admet-2766	287	5	and	and	CCONJ
admet-2766	287	6	18	18	NUM
admet-2766	287	7	l1	l1	PROPN
admet-2766	287	8	genes	gene	NOUN
admet-2766	287	9	by	by	ADP
admet-2766	287	10	a	a	DET
admet-2766	287	11	nucleic	nucleic	ADJ
admet-2766	287	12	acid	acid	NOUN
admet-2766	287	13	amplification	amplification	NOUN
admet-2766	287	14	-	-	PUNCT
admet-2766	287	15	free	free	ADJ
admet-2766	287	16	electrochemical	electrochemical	ADJ
admet-2766	287	17	biosensor	biosensor	NOUN
admet-2766	287	18	powered	power	VERB
admet-2766	287	19	by	by	ADP
admet-2766	287	20	crispr	crispr	PROPN
admet-2766	287	21	/	/	SYM
admet-2766	287	22	cas9	cas9	NOUN
admet-2766	287	23	.	.	PUNCT
admet-2766	288	1	bioelectrochemistry	bioelectrochemistry	NOUN
admet-2766	288	2	162	162	NUM
admet-2766	288	3	(	(	PUNCT
admet-2766	288	4	2025	2025	NUM
admet-2766	288	5	)	)	PUNCT
admet-2766	288	6	108861	108861	NUM
admet-2766	288	7	.	.	PUNCT
admet-2766	289	1	https://doi.org/10.1016/j.bioelechem.2024.108861	https://doi.org/10.1016/j.bioelechem.2024.108861	NOUN
admet-2766	289	2	[	[	X
admet-2766	289	3	29	29	NUM
admet-2766	289	4	]	]	X
admet-2766	289	5	national	national	ADJ
admet-2766	289	6	center	center	NOUN
admet-2766	289	7	for	for	ADP
admet-2766	289	8	biotechnology	biotechnology	NOUN
admet-2766	289	9	information	information	NOUN
admet-2766	289	10	(	(	PUNCT
admet-2766	289	11	ncbi	ncbi	NOUN
admet-2766	289	12	)	)	PUNCT
admet-2766	289	13	.	.	PUNCT
admet-2766	290	1	ncbi	ncbi	PROPN
admet-2766	290	2	nucleotide	nucleotide	PROPN
admet-2766	290	3	:	:	PUNCT
admet-2766	290	4	al123456.3	al123456.3	X
admet-2766	290	5	mycobacterium	mycobacterium	NOUN
admet-2766	290	6	tuberculosis	tuberculosis	NOUN
admet-2766	290	7	h37rv	h37rv	ADP
admet-2766	290	8	complete	complete	ADJ
admet-2766	290	9	genome	genome	NOUN
admet-2766	290	10	.	.	PUNCT
admet-2766	291	1	https://www.ncbi.nlm.nih.gov/nuccore/al123456.3	https://www.ncbi.nlm.nih.gov/nuccore/al123456.3	PROPN
admet-2766	291	2	(	(	PUNCT
admet-2766	291	3	accessed	access	VERB
admet-2766	291	4	november	november	PROPN
admet-2766	291	5	2	2	NUM
admet-2766	291	6	,	,	PUNCT
admet-2766	291	7	2023	2023	NUM
admet-2766	291	8	)	)	PUNCT
admet-2766	292	1	[	[	X
admet-2766	292	2	30	30	NUM
admet-2766	292	3	]	]	X
admet-2766	292	4	national	national	ADJ
admet-2766	292	5	center	center	NOUN
admet-2766	292	6	for	for	ADP
admet-2766	292	7	biotechnology	biotechnology	NOUN
admet-2766	292	8	information	information	NOUN
admet-2766	292	9	(	(	PUNCT
admet-2766	292	10	ncbi	ncbi	NOUN
admet-2766	292	11	)	)	PUNCT
admet-2766	292	12	.	.	PUNCT
admet-2766	293	1	ncbi	ncbi	PROPN
admet-2766	293	2	nucleotide	nucleotide	PROPN
admet-2766	293	3	:	:	PUNCT
admet-2766	293	4	al123456.3	al123456.3	X
admet-2766	293	5	mycobacterium	mycobacterium	NOUN
admet-2766	293	6	tuberculosis	tuberculosis	NOUN
admet-2766	293	7	h37rv	h37rv	ADP
admet-2766	293	8	complete	complete	ADJ
admet-2766	293	9	genome	genome	NOUN
admet-2766	293	10	(	(	PUNCT
admet-2766	293	11	rpob	rpob	ADJ
admet-2766	293	12	gene	gene	NOUN
admet-2766	293	13	)	)	PUNCT
admet-2766	293	14	.	.	PUNCT
admet-2766	294	1	https://www.ncbi.nlm.nih.gov/nuccore/al123456.3?from=759807&to=76332%205	https://www.ncbi.nlm.nih.gov/nuccore/al123456.3?from=759807&to=76332%205	X
admet-2766	294	2	(	(	PUNCT
admet-2766	294	3	accessed	access	VERB
admet-2766	294	4	november	november	PROPN
admet-2766	294	5	2	2	NUM
admet-2766	294	6	,	,	PUNCT
admet-2766	294	7	2023	2023	NUM
admet-2766	294	8	)	)	PUNCT
admet-2766	295	1	[	[	X
admet-2766	295	2	31	31	NUM
admet-2766	295	3	]	]	X
admet-2766	295	4	national	national	ADJ
admet-2766	295	5	center	center	NOUN
admet-2766	295	6	for	for	ADP
admet-2766	295	7	biotechnology	biotechnology	NOUN
admet-2766	295	8	information	information	NOUN
admet-2766	295	9	(	(	PUNCT
admet-2766	295	10	ncbi	ncbi	NOUN
admet-2766	295	11	)	)	PUNCT
admet-2766	295	12	.	.	PUNCT
admet-2766	296	1	ncbi	ncbi	PROPN
admet-2766	296	2	nucleotide	nucleotide	PROPN
admet-2766	296	3	:	:	PUNCT
admet-2766	296	4	x68081.1	x68081.1	X
admet-2766	297	1	mycobacterium	mycobacterium	NOUN
admet-2766	297	2	tuberculosis	tuberculosis	NOUN
admet-2766	297	3	gene	gene	NOUN
admet-2766	297	4	for	for	ADP
admet-2766	297	5	catalase	catalase	NOUN
admet-2766	297	6	-	-	PUNCT
admet-2766	297	7	peroxidase	peroxidase	NOUN
admet-2766	297	8	(	(	PUNCT
admet-2766	297	9	katg	katg	PROPN
admet-2766	297	10	)	)	PUNCT
admet-2766	297	11	.	.	PUNCT
admet-2766	298	1	https://www.ncbi.nlm.nih.gov/nuccore/x68081.1	https://www.ncbi.nlm.nih.gov/nuccore/x68081.1	NOUN
admet-2766	298	2	(	(	PUNCT
admet-2766	298	3	accessed	access	VERB
admet-2766	298	4	november	november	PROPN
admet-2766	298	5	2	2	NUM
admet-2766	298	6	,	,	PUNCT
admet-2766	298	7	2023	2023	NUM
admet-2766	298	8	)	)	PUNCT
admet-2766	298	9	.	.	PUNCT
admet-2766	299	1	[	[	X
admet-2766	299	2	32	32	NUM
admet-2766	299	3	]	]	PUNCT
admet-2766	299	4	m.	m.	NOUN
admet-2766	299	5	haeussler	haeussler	NOUN
admet-2766	299	6	,	,	PUNCT
admet-2766	299	7	k.	k.	PROPN
admet-2766	299	8	schönig	schönig	PROPN
admet-2766	299	9	,	,	PUNCT
admet-2766	299	10	h.	h.	PROPN
admet-2766	299	11	eckert	eckert	PROPN
admet-2766	299	12	,	,	PUNCT
admet-2766	299	13	a.	a.	PROPN
admet-2766	299	14	eschstruth	eschstruth	PROPN
admet-2766	299	15	,	,	PUNCT
admet-2766	299	16	j.	j.	PROPN
admet-2766	299	17	mianné	mianné	PROPN
admet-2766	299	18	,	,	PUNCT
admet-2766	299	19	j.b	j.b	PROPN
admet-2766	299	20	.	.	PROPN
admet-2766	299	21	renaud	renaud	PROPN
admet-2766	299	22	,	,	PUNCT
admet-2766	299	23	s.	s.	PROPN
admet-2766	299	24	schneider	schneider	PROPN
admet-2766	299	25	-	-	PUNCT
admet-2766	299	26	maunoury	maunoury	PROPN
admet-2766	299	27	,	,	PUNCT
admet-2766	299	28	a.	a.	PROPN
admet-2766	299	29	shkumatava	shkumatava	PROPN
admet-2766	299	30	,	,	PUNCT
admet-2766	299	31	l.	l.	PROPN
admet-2766	299	32	teboul	teboul	PROPN
admet-2766	299	33	,	,	PUNCT
admet-2766	299	34	j.	j.	PROPN
admet-2766	299	35	kent	kent	PROPN
admet-2766	299	36	,	,	PUNCT
admet-2766	299	37	j.s	j.s	PROPN
admet-2766	299	38	.	.	PROPN
admet-2766	299	39	joly	joly	PROPN
admet-2766	299	40	,	,	PUNCT
admet-2766	299	41	j.p	j.p	PROPN
admet-2766	299	42	.	.	PROPN
admet-2766	299	43	concordet	concordet	PROPN
admet-2766	299	44	.	.	PUNCT
admet-2766	300	1	evaluation	evaluation	NOUN
admet-2766	300	2	of	of	ADP
admet-2766	300	3	off	off	ADP
admet-2766	300	4	-	-	PUNCT
admet-2766	300	5	target	target	NOUN
admet-2766	300	6	and	and	CCONJ
admet-2766	300	7	on	on	ADP
admet-2766	300	8	-	-	PUNCT
admet-2766	300	9	target	target	NOUN
admet-2766	300	10	scoring	scoring	NOUN
admet-2766	300	11	algorithms	algorithm	NOUN
admet-2766	300	12	and	and	CCONJ
admet-2766	300	13	integration	integration	NOUN
admet-2766	300	14	into	into	ADP
admet-2766	300	15	the	the	DET
admet-2766	300	16	guide	guide	NOUN
admet-2766	300	17	rna	rna	NOUN
admet-2766	300	18	selection	selection	NOUN
admet-2766	300	19	tool	tool	NOUN
admet-2766	300	20	crispor	crispor	NOUN
admet-2766	300	21	.	.	PUNCT
admet-2766	301	1	genome	genome	NOUN
admet-2766	301	2	biology	biology	NOUN
admet-2766	301	3	17	17	NUM
admet-2766	301	4	(	(	PUNCT
admet-2766	301	5	2016	2016	NUM
admet-2766	301	6	)	)	PUNCT
admet-2766	301	7	148	148	NUM
admet-2766	301	8	.	.	PUNCT
admet-2766	302	1	https://doi.org/10.1186/s13059-016-1012-2	https://doi.org/10.1186/s13059-016-1012-2	X
admet-2766	303	1	[	[	X
admet-2766	303	2	33	33	NUM
admet-2766	303	3	]	]	X
admet-2766	303	4	j.g	j.g	PROPN
admet-2766	303	5	.	.	PROPN
admet-2766	303	6	doench	doench	PROPN
admet-2766	303	7	,	,	PUNCT
admet-2766	303	8	n.	n.	NOUN
admet-2766	303	9	fusi	fusi	PROPN
admet-2766	303	10	,	,	PUNCT
admet-2766	303	11	m.	m.	NOUN
admet-2766	303	12	sullender	sullender	PROPN
admet-2766	303	13	,	,	PUNCT
admet-2766	303	14	m.	m.	NOUN
admet-2766	303	15	hedge	hedge	PROPN
admet-2766	303	16	,	,	PUNCT
admet-2766	303	17	e.w	e.w	PROPN
admet-2766	303	18	.	.	PROPN
admet-2766	303	19	vaimberg	vaimberg	PROPN
admet-2766	303	20	,	,	PUNCT
admet-2766	303	21	k.f	k.f	PROPN
admet-2766	303	22	.	.	PROPN
admet-2766	303	23	donovan	donovan	PROPN
admet-2766	303	24	,	,	PUNCT
admet-2766	303	25	i.	i.	PROPN
admet-2766	303	26	smith	smith	PROPN
admet-2766	303	27	,	,	PUNCT
admet-2766	303	28	z.	z.	PROPN
admet-2766	303	29	tothova	tothova	PROPN
admet-2766	303	30	,	,	PUNCT
admet-2766	303	31	c.	c.	PROPN
admet-2766	303	32	wilen	wilen	PROPN
admet-2766	303	33	,	,	PUNCT
admet-2766	303	34	r.	r.	NOUN
admet-2766	303	35	orchard	orchard	PROPN
admet-2766	303	36	,	,	PUNCT
admet-2766	303	37	h.w	h.w	PROPN
admet-2766	303	38	.	.	PROPN
admet-2766	303	39	virgin	virgin	PROPN
admet-2766	303	40	,	,	PUNCT
admet-2766	303	41	j.	j.	PROPN
admet-2766	303	42	listgarten	listgarten	PROPN
admet-2766	303	43	,	,	PUNCT
admet-2766	303	44	d.e	d.e	PROPN
admet-2766	303	45	.	.	PROPN
admet-2766	303	46	root	root	PROPN
admet-2766	303	47	.	.	PUNCT
admet-2766	304	1	optimized	optimize	VERB
admet-2766	304	2	sgrna	sgrna	NOUN
admet-2766	304	3	design	design	NOUN
admet-2766	304	4	to	to	PART
admet-2766	304	5	maximize	maximize	VERB
admet-2766	304	6	activity	activity	NOUN
admet-2766	304	7	and	and	CCONJ
admet-2766	304	8	minimize	minimize	VERB
admet-2766	304	9	off	off	ADP
admet-2766	304	10	-	-	PUNCT
admet-2766	304	11	target	target	NOUN
admet-2766	304	12	effects	effect	NOUN
admet-2766	304	13	of	of	ADP
admet-2766	304	14	crispr	crispr	NOUN
admet-2766	304	15	-	-	PUNCT
admet-2766	304	16	cas9	cas9	NOUN
admet-2766	304	17	.	.	PUNCT
admet-2766	305	1	nature	nature	NOUN
admet-2766	305	2	biotechnology	biotechnology	NOUN
admet-2766	305	3	34	34	NUM
admet-2766	305	4	(	(	PUNCT
admet-2766	305	5	2016	2016	NUM
admet-2766	305	6	)	)	PUNCT
admet-2766	305	7	184	184	NUM
admet-2766	305	8	-	-	SYM
admet-2766	305	9	191	191	NUM
admet-2766	305	10	.	.	PUNCT
admet-2766	306	1	https://doi.org/10.1038/nbt.3437	https://doi.org/10.1038/nbt.3437	PROPN
admet-2766	306	2	[	[	X
admet-2766	306	3	34	34	NUM
admet-2766	306	4	]	]	X
admet-2766	306	5	p.d	p.d	PROPN
admet-2766	306	6	.	.	PROPN
admet-2766	306	7	hsu	hsu	PROPN
admet-2766	306	8	,	,	PUNCT
admet-2766	306	9	d.a	d.a	PROPN
admet-2766	306	10	.	.	PROPN
admet-2766	306	11	scott	scott	PROPN
admet-2766	306	12	,	,	PUNCT
admet-2766	306	13	j.a	j.a	PROPN
admet-2766	306	14	.	.	PROPN
admet-2766	306	15	weinstein	weinstein	PROPN
admet-2766	306	16	,	,	PUNCT
admet-2766	306	17	f.a	f.a	PROPN
admet-2766	306	18	.	.	PROPN
admet-2766	306	19	ran	run	VERB
admet-2766	306	20	,	,	PUNCT
admet-2766	306	21	s.	s.	PROPN
admet-2766	306	22	konermann	konermann	PROPN
admet-2766	306	23	,	,	PUNCT
admet-2766	306	24	v.	v.	ADP
admet-2766	306	25	agarwala	agarwala	NOUN
admet-2766	306	26	,	,	PUNCT
admet-2766	306	27	y.	y.	PROPN
admet-2766	306	28	li	li	PROPN
admet-2766	306	29	,	,	PUNCT
admet-2766	306	30	e.j	e.j	PROPN
admet-2766	306	31	.	.	PROPN
admet-2766	306	32	fine	fine	PROPN
admet-2766	306	33	,	,	PUNCT
admet-2766	306	34	x.	x.	PROPN
admet-2766	306	35	wu	wu	PROPN
admet-2766	306	36	,	,	PUNCT
admet-2766	306	37	o.	o.	PROPN
admet-2766	306	38	shalem	shalem	PROPN
admet-2766	306	39	,	,	PUNCT
admet-2766	306	40	t.j	t.j	PROPN
admet-2766	306	41	.	.	PROPN
admet-2766	306	42	cradick	cradick	PROPN
admet-2766	306	43	,	,	PUNCT
admet-2766	306	44	l.a	l.a	PROPN
admet-2766	306	45	.	.	PROPN
admet-2766	306	46	marraffini	marraffini	PROPN
admet-2766	306	47	,	,	PUNCT
admet-2766	306	48	g.	g.	PROPN
admet-2766	306	49	bao	bao	PROPN
admet-2766	306	50	,	,	PUNCT
admet-2766	306	51	f.	f.	PROPN
admet-2766	306	52	zhang	zhang	PROPN
admet-2766	306	53	.	.	PUNCT
admet-2766	307	1	dna	dna	PROPN
admet-2766	307	2	targeting	target	VERB
admet-2766	307	3	specificity	specificity	NOUN
admet-2766	307	4	of	of	ADP
admet-2766	307	5	rna	rna	NOUN
admet-2766	307	6	-	-	PUNCT
admet-2766	307	7	guided	guide	VERB
admet-2766	307	8	cas9	cas9	NOUN
admet-2766	307	9	nucleases	nuclease	NOUN
admet-2766	307	10	.	.	PUNCT
admet-2766	308	1	nature	nature	NOUN
admet-2766	308	2	biotechnology	biotechnology	NOUN
admet-2766	308	3	31	31	NUM
admet-2766	308	4	(	(	PUNCT
admet-2766	308	5	2013	2013	NUM
admet-2766	308	6	)	)	PUNCT
admet-2766	308	7	827	827	NUM
admet-2766	308	8	-	-	SYM
admet-2766	308	9	832	832	NUM
admet-2766	308	10	.	.	PUNCT
admet-2766	309	1	https://doi.org/10.1038/nbt.2647	https://doi.org/10.1038/nbt.2647	PROPN
admet-2766	310	1	[	[	X
admet-2766	310	2	35	35	NUM
admet-2766	310	3	]	]	PUNCT
admet-2766	310	4	t.	t.	PROPN
admet-2766	310	5	zheng	zheng	PROPN
admet-2766	310	6	,	,	PUNCT
admet-2766	310	7	y.	y.	PROPN
admet-2766	310	8	hou	hou	PROPN
admet-2766	310	9	,	,	PUNCT
admet-2766	310	10	p.	p.	PROPN
admet-2766	310	11	zhang	zhang	PROPN
admet-2766	310	12	,	,	PUNCT
admet-2766	310	13	z.	z.	PROPN
admet-2766	310	14	zhang	zhang	PROPN
admet-2766	310	15	,	,	PUNCT
admet-2766	310	16	y.	y.	PROPN
admet-2766	310	17	xu	xu	PROPN
admet-2766	310	18	,	,	PUNCT
admet-2766	310	19	l.	l.	PROPN
admet-2766	310	20	zhang	zhang	PROPN
admet-2766	310	21	,	,	PUNCT
admet-2766	310	22	l.	l.	PROPN
admet-2766	310	23	niu	niu	PROPN
admet-2766	310	24	,	,	PUNCT
admet-2766	310	25	y.	y.	PROPN
admet-2766	310	26	yang	yang	PROPN
admet-2766	310	27	,	,	PUNCT
admet-2766	310	28	d.	d.	PROPN
admet-2766	310	29	liang	liang	PROPN
admet-2766	310	30	,	,	PUNCT
admet-2766	310	31	f.	f.	PROPN
admet-2766	310	32	yi	yi	PROPN
admet-2766	310	33	,	,	PUNCT
admet-2766	310	34	w.	w.	PROPN
admet-2766	310	35	peng	peng	PROPN
admet-2766	310	36	,	,	PUNCT
admet-2766	310	37	w.	w.	PROPN
admet-2766	310	38	feng	feng	PROPN
admet-2766	310	39	,	,	PUNCT
admet-2766	310	40	y.	y.	PROPN
admet-2766	310	41	yang	yang	PROPN
admet-2766	310	42	,	,	PUNCT
admet-2766	310	43	j.	j.	PROPN
admet-2766	310	44	chen	chen	PROPN
admet-2766	310	45	,	,	PUNCT
admet-2766	310	46	y.y	y.y	PROPN
admet-2766	310	47	.	.	PROPN
admet-2766	310	48	zhu	zhu	PROPN
admet-2766	310	49	,	,	PUNCT
admet-2766	310	50	l.h	l.h	PROPN
admet-2766	310	51	.	.	PROPN
admet-2766	310	52	zhang	zhang	PROPN
admet-2766	310	53	,	,	PUNCT
admet-2766	310	54	q.	q.	PROPN
admet-2766	310	55	du	du	PROPN
admet-2766	310	56	.	.	PUNCT
admet-2766	310	57	profiling	profile	VERB
admet-2766	310	58	single	single	ADJ
admet-2766	310	59	-	-	PUNCT
admet-2766	310	60	guide	guide	NOUN
admet-2766	310	61	rna	rna	NOUN
admet-2766	310	62	specificity	specificity	NOUN
admet-2766	310	63	reveals	reveal	VERB
admet-2766	310	64	a	a	DET
admet-2766	310	65	mismatch	mismatch	ADJ
admet-2766	310	66	sensitive	sensitive	ADJ
admet-2766	310	67	core	core	NOUN
admet-2766	310	68	sequence	sequence	NOUN
admet-2766	310	69	.	.	PUNCT
admet-2766	311	1	scientific	scientific	ADJ
admet-2766	311	2	reports	report	NOUN
admet-2766	311	3	8	8	NUM
admet-2766	311	4	(	(	PUNCT
admet-2766	311	5	2017	2017	NUM
admet-2766	311	6	)	)	PUNCT
admet-2766	311	7	40638	40638	NUM
admet-2766	311	8	.	.	PUNCT
admet-2766	312	1	https://doi.org/10.1038/srep40638	https://doi.org/10.1038/srep40638	PROPN
admet-2766	312	2	[	[	X
admet-2766	312	3	36	36	NUM
admet-2766	312	4	]	]	X
admet-2766	312	5	s.c	s.c	PROPN
admet-2766	312	6	.	.	PROPN
admet-2766	312	7	strutt	strutt	PROPN
admet-2766	312	8	,	,	PUNCT
admet-2766	312	9	r.m	r.m	PROPN
admet-2766	312	10	.	.	PROPN
admet-2766	312	11	torrez	torrez	PROPN
admet-2766	312	12	,	,	PUNCT
admet-2766	312	13	e.	e.	PROPN
admet-2766	312	14	kaya	kaya	PROPN
admet-2766	312	15	,	,	PUNCT
admet-2766	312	16	o.a	o.a	PROPN
admet-2766	312	17	.	.	PROPN
admet-2766	312	18	negrete	negrete	PROPN
admet-2766	312	19	,	,	PUNCT
admet-2766	312	20	doudna	doudna	PROPN
admet-2766	312	21	.	.	PUNCT
admet-2766	313	1	jennifer	jennifer	PROPN
admet-2766	313	2	a.	a.	PROPN
admet-2766	313	3	rna	rna	PROPN
admet-2766	313	4	-	-	PUNCT
admet-2766	313	5	dependent	dependent	ADJ
admet-2766	313	6	rna	rna	NOUN
admet-2766	313	7	targeting	target	VERB
admet-2766	313	8	by	by	ADP
admet-2766	313	9	crispr	crispr	NOUN
admet-2766	313	10	-	-	PUNCT
admet-2766	313	11	cas9	cas9	NOUN
admet-2766	313	12	.	.	PUNCT
admet-2766	314	1	elife	elife	NOUN
admet-2766	314	2	7	7	NUM
admet-2766	314	3	(	(	PUNCT
admet-2766	314	4	2018	2018	NUM
admet-2766	314	5	)	)	PUNCT
admet-2766	314	6	e32724	e32724	NOUN
admet-2766	314	7	.	.	PUNCT
admet-2766	315	1	https://doi.org/10.7554/elife.32724	https://doi.org/10.7554/elife.32724	X
admet-2766	315	2	[	[	X
admet-2766	315	3	37	37	NUM
admet-2766	315	4	]	]	PUNCT
admet-2766	315	5	m.	m.	NOUN
admet-2766	315	6	zhou	zhou	PROPN
admet-2766	315	7	,	,	PUNCT
admet-2766	315	8	x.	x.	PROPN
admet-2766	315	9	li	li	PROPN
admet-2766	315	10	,	,	PUNCT
admet-2766	315	11	h.	h.	PROPN
admet-2766	315	12	wen	wen	PROPN
admet-2766	315	13	,	,	PUNCT
admet-2766	315	14	b.	b.	PROPN
admet-2766	315	15	huang	huang	PROPN
admet-2766	315	16	,	,	PUNCT
admet-2766	315	17	j.	j.	PROPN
admet-2766	315	18	ren	ren	PROPN
admet-2766	315	19	,	,	PUNCT
admet-2766	315	20	j.	j.	PROPN
admet-2766	315	21	zhang	zhang	PROPN
admet-2766	315	22	.	.	PUNCT
admet-2766	316	1	the	the	DET
admet-2766	316	2	construction	construction	NOUN
admet-2766	316	3	of	of	ADP
admet-2766	316	4	crispr	crispr	ADJ
admet-2766	316	5	/	/	SYM
admet-2766	316	6	cas9	cas9	NOUN
admet-2766	316	7	-	-	PUNCT
admet-2766	316	8	mediated	mediate	VERB
admet-2766	316	9	fret	fret	NOUN
admet-2766	316	10	16s	16s	PROPN
admet-2766	316	11	rdna	rdna	PROPN
admet-2766	316	12	sensor	sensor	NOUN
admet-2766	316	13	for	for	ADP
admet-2766	316	14	detection	detection	NOUN
admet-2766	316	15	of	of	ADP
admet-2766	316	16	mycobacterium	mycobacterium	NOUN
admet-2766	316	17	tuberculosis	tuberculosis	NOUN
admet-2766	316	18	.	.	PUNCT
admet-2766	317	1	analyst	analyst	NOUN
admet-2766	317	2	148	148	NUM
admet-2766	317	3	(	(	PUNCT
admet-2766	317	4	2023	2023	NUM
admet-2766	317	5	)	)	PUNCT
admet-2766	317	6	2308	2308	NUM
admet-2766	317	7	-	-	SYM
admet-2766	317	8	2315	2315	NUM
admet-2766	317	9	.	.	PUNCT
admet-2766	318	1	https://doi.org/10.1039/d3an00462	https://doi.org/10.1039/d3an00462	NOUN
admet-2766	318	2	g	g	PROPN
admet-2766	318	3	[	[	X
admet-2766	318	4	38	38	NUM
admet-2766	318	5	]	]	PUNCT
admet-2766	318	6	j.	j.	PROPN
admet-2766	318	7	huang	huang	PROPN
admet-2766	318	8	,	,	PUNCT
admet-2766	318	9	z.	z.	PROPN
admet-2766	318	10	liang	liang	PROPN
admet-2766	318	11	,	,	PUNCT
admet-2766	318	12	y.	y.	PROPN
admet-2766	318	13	liu	liu	PROPN
admet-2766	318	14	,	,	PUNCT
admet-2766	318	15	j.	j.	PROPN
admet-2766	318	16	zhou	zhou	PROPN
admet-2766	318	17	,	,	PUNCT
admet-2766	318	18	f.	f.	PROPN
admet-2766	318	19	he	he	PRON
admet-2766	318	20	.	.	PUNCT
admet-2766	319	1	development	development	NOUN
admet-2766	319	2	of	of	ADP
admet-2766	319	3	an	an	DET
admet-2766	319	4	mspqc	mspqc	ADJ
admet-2766	319	5	nucleic	nucleic	ADJ
admet-2766	319	6	acid	acid	NOUN
admet-2766	319	7	sensor	sensor	NOUN
admet-2766	319	8	based	base	VERB
admet-2766	319	9	on	on	ADP
admet-2766	319	10	crispr	crispr	PROPN
admet-2766	319	11	/	/	SYM
admet-2766	319	12	cas9	cas9	NOUN
admet-2766	319	13	for	for	ADP
admet-2766	319	14	the	the	DET
admet-2766	319	15	detection	detection	NOUN
admet-2766	319	16	of	of	ADP
admet-2766	319	17	mycobacterium	mycobacterium	NOUN
admet-2766	319	18	tuberculosis	tuberculosis	NOUN
admet-2766	319	19	.	.	PUNCT
admet-2766	320	1	analytical	analytical	ADJ
admet-2766	320	2	chemistry	chemistry	NOUN
admet-2766	320	3	94	94	NUM
admet-2766	320	4	(	(	PUNCT
admet-2766	320	5	2022	2022	NUM
admet-2766	320	6	)	)	PUNCT
admet-2766	320	7	1140911415	1140911415	NUM
admet-2766	320	8	.	.	PUNCT
admet-2766	321	1	https://doi.org/10.1021/acs.analchem.2c02538	https://doi.org/10.1021/acs.analchem.2c02538	NOUN
admet-2766	321	2	https://doi.org/10.5599/admet.2766	https://doi.org/10.5599/admet.2766	PROPN
admet-2766	321	3	https://doi.org/10.1099/mic.0.023960-0	https://doi.org/10.1099/mic.0.023960-0	NOUN
admet-2766	321	4	https://doi.org/10.1186/s13059-015-0784-0	https://doi.org/10.1186/s13059-015-0784-0	NUM
admet-2766	321	5	https://doi.org/10.1016/j.gene.2023.147173	https://doi.org/10.1016/j.gene.2023.147173	NOUN
admet-2766	321	6	https://doi.org/10.3390/bios11010017	https://doi.org/10.3390/bios11010017	VERB
admet-2766	321	7	https://doi.org/10.1016/j.sbsr.2025.100755	https://doi.org/10.1016/j.sbsr.2025.100755	ADJ
admet-2766	321	8	https://doi.org/10.1016/j.bioelechem.2024.108861	https://doi.org/10.1016/j.bioelechem.2024.108861	NOUN
admet-2766	321	9	https://www.ncbi.nlm.nih.gov/nuccore/al123456.3	https://www.ncbi.nlm.nih.gov/nuccore/al123456.3	PROPN
admet-2766	321	10	https://www.ncbi.nlm.nih.gov/nuccore/al123456.3?from=759807&to=76332%205	https://www.ncbi.nlm.nih.gov/nuccore/al123456.3?from=759807&to=76332%205	VERB
admet-2766	321	11	https://www.ncbi.nlm.nih.gov/nuccore/x68081.1	https://www.ncbi.nlm.nih.gov/nuccore/x68081.1	NOUN
admet-2766	321	12	https://doi.org/10.1186/s13059-016-1012-2	https://doi.org/10.1186/s13059-016-1012-2	PROPN
admet-2766	321	13	https://doi.org/10.1038/nbt.3437	https://doi.org/10.1038/nbt.3437	PROPN
admet-2766	321	14	https://doi.org/10.1038/nbt.2647	https://doi.org/10.1038/nbt.2647	ADJ
admet-2766	321	15	https://doi.org/10.1038/srep40638	https://doi.org/10.1038/srep40638	NOUN
admet-2766	321	16	https://doi.org/10.7554/elife.32724	https://doi.org/10.7554/elife.32724	NOUN
admet-2766	321	17	https://doi.org/10.1039/d3an00462	https://doi.org/10.1039/d3an00462	NOUN
admet-2766	321	18	g	g	PROPN
admet-2766	321	19	https://doi.org/10.1021/acs.analchem.2c02538	https://doi.org/10.1021/acs.analchem.2c02538	NUM
admet-2766	321	20	d.	d.	PROPN
admet-2766	321	21	a.	a.	NOUN
admet-2766	322	1	wulandari	wulandari	PROPN
admet-2766	322	2	et	et	PROPN
admet-2766	322	3	al	al	PROPN
admet-2766	322	4	.	.	PROPN
admet-2766	322	5	admet	admet	PROPN
admet-2766	322	6	&	&	CCONJ
admet-2766	322	7	dmpk	dmpk	PROPN
admet-2766	322	8	13(3	13(3	NUM
admet-2766	322	9	)	)	PUNCT
admet-2766	322	10	(	(	PUNCT
admet-2766	322	11	2025	2025	NUM
admet-2766	322	12	)	)	PUNCT
admet-2766	322	13	2766	2766	NUM
admet-2766	322	14	14	14	NUM
admet-2766	323	1	[	[	X
admet-2766	323	2	39	39	NUM
admet-2766	323	3	]	]	X
admet-2766	323	4	s.n	s.n	PROPN
admet-2766	323	5	.	.	PROPN
admet-2766	323	6	zakiyyah	zakiyyah	PROPN
admet-2766	323	7	,	,	PUNCT
admet-2766	323	8	n.p	n.p	PROPN
admet-2766	323	9	.	.	PROPN
admet-2766	323	10	satriana	satriana	PROPN
admet-2766	323	11	,	,	PUNCT
admet-2766	323	12	n.	n.	NOUN
admet-2766	323	13	fransisca	fransisca	PROPN
admet-2766	323	14	,	,	PUNCT
admet-2766	323	15	s.	s.	PROPN
admet-2766	323	16	gaffar	gaffar	PROPN
admet-2766	323	17	,	,	PUNCT
admet-2766	323	18	n.	n.	NOUN
admet-2766	323	19	syakir	syakir	NOUN
admet-2766	323	20	,	,	PUNCT
admet-2766	323	21	irkham	irkham	NOUN
admet-2766	323	22	,	,	PUNCT
admet-2766	323	23	y.w	y.w	PROPN
admet-2766	323	24	.	.	PROPN
admet-2766	323	25	hartati	hartati	PROPN
admet-2766	323	26	.	.	PUNCT
admet-2766	324	1	gold	gold	NOUN
admet-2766	324	2	nanoparticlemodified	nanoparticlemodifie	VERB
admet-2766	324	3	screen	screen	NOUN
admet-2766	324	4	-	-	PUNCT
admet-2766	324	5	printed	print	VERB
admet-2766	324	6	carbon	carbon	NOUN
admet-2766	324	7	electrodes	electrode	VERB
admet-2766	324	8	for	for	ADP
admet-2766	324	9	label	label	NOUN
admet-2766	324	10	-	-	PUNCT
admet-2766	324	11	free	free	ADJ
admet-2766	324	12	detection	detection	NOUN
admet-2766	324	13	of	of	ADP
admet-2766	324	14	sars	sar	NOUN
admet-2766	324	15	-	-	PUNCT
admet-2766	324	16	cov-2	cov-2	NOUN
admet-2766	324	17	rna	rna	NOUN
admet-2766	324	18	using	use	VERB
admet-2766	324	19	drop	drop	NOUN
admet-2766	324	20	casting	cast	VERB
admet-2766	324	21	and	and	CCONJ
admet-2766	324	22	spray	spray	VERB
admet-2766	324	23	coating	coating	NOUN
admet-2766	324	24	methods	method	NOUN
admet-2766	324	25	.	.	PUNCT
admet-2766	325	1	admet	admet	PROPN
admet-2766	325	2	&	&	CCONJ
admet-2766	325	3	dmpk	dmpk	PROPN
admet-2766	325	4	13	13	NUM
admet-2766	325	5	(	(	PUNCT
admet-2766	325	6	2025	2025	NUM
admet-2766	325	7	)	)	PUNCT
admet-2766	325	8	2577	2577	NUM
admet-2766	325	9	.	.	PUNCT
admet-2766	325	10	https://doi.org/10.5599/admet.2577	https://doi.org/10.5599/admet.2577	X
admet-2766	326	1	[	[	X
admet-2766	326	2	40	40	NUM
admet-2766	326	3	]	]	X
admet-2766	326	4	c.j	c.j	PROPN
admet-2766	326	5	.	.	PROPN
admet-2766	326	6	weber	weber	PROPN
admet-2766	326	7	,	,	PUNCT
admet-2766	326	8	n.e	n.e	PROPN
admet-2766	326	9	.	.	PROPN
admet-2766	326	10	strom	strom	PROPN
admet-2766	326	11	,	,	PUNCT
admet-2766	326	12	o.	o.	PROPN
admet-2766	326	13	simoska	simoska	PROPN
admet-2766	326	14	.	.	PUNCT
admet-2766	327	1	electrochemical	electrochemical	ADJ
admet-2766	327	2	deposition	deposition	NOUN
admet-2766	327	3	of	of	ADP
admet-2766	327	4	gold	gold	ADJ
admet-2766	327	5	nanoparticles	nanoparticle	NOUN
admet-2766	327	6	on	on	ADP
admet-2766	327	7	carbon	carbon	NOUN
admet-2766	327	8	ultramicroelectrode	ultramicroelectrode	NOUN
admet-2766	327	9	arrays	array	VERB
admet-2766	327	10	.	.	PUNCT
admet-2766	328	1	nanoscale	nanoscale	NOUN
admet-2766	328	2	16	16	NUM
admet-2766	328	3	(	(	PUNCT
admet-2766	328	4	2024	2024	NUM
admet-2766	328	5	)	)	PUNCT
admet-2766	328	6	16204	16204	NUM
admet-2766	328	7	-	-	SYM
admet-2766	328	8	16217	16217	NUM
admet-2766	328	9	.	.	PUNCT
admet-2766	329	1	https://doi.org/10.1039/d4nr02326a	https://doi.org/10.1039/d4nr02326a	PUNCT
admet-2766	329	2	[	[	X
admet-2766	329	3	41	41	NUM
admet-2766	329	4	]	]	PUNCT
admet-2766	329	5	s.	s.	PROPN
admet-2766	329	6	zuliska	zuliska	PROPN
admet-2766	329	7	,	,	PUNCT
admet-2766	329	8	irkham	irkham	NOUN
admet-2766	329	9	,	,	PUNCT
admet-2766	329	10	s.n	s.n	PROPN
admet-2766	329	11	.	.	PROPN
admet-2766	329	12	zakiyyah	zakiyyah	PROPN
admet-2766	329	13	,	,	PUNCT
admet-2766	329	14	y.w	y.w	PROPN
admet-2766	329	15	.	.	PROPN
admet-2766	329	16	hartati	hartati	PROPN
admet-2766	329	17	,	,	PUNCT
admet-2766	329	18	y.einaga	y.einaga	NOUN
admet-2766	329	19	,	,	PUNCT
admet-2766	329	20	i.p.maksum	i.p.maksum	NOUN
admet-2766	329	21	.	.	PUNCT
admet-2766	330	1	electrochemical	electrochemical	ADJ
admet-2766	330	2	aptasensor	aptasensor	NOUN
admet-2766	330	3	for	for	ADP
admet-2766	330	4	ultrasensitive	ultrasensitive	ADJ
admet-2766	330	5	detection	detection	NOUN
admet-2766	330	6	of	of	ADP
admet-2766	330	7	glycated	glycate	VERB
admet-2766	330	8	hemoglobin	hemoglobin	NOUN
admet-2766	330	9	(	(	PUNCT
admet-2766	330	10	hba1c	hba1c	PROPN
admet-2766	330	11	)	)	PUNCT
admet-2766	330	12	using	use	VERB
admet-2766	330	13	gold	gold	NOUN
admet-2766	330	14	-	-	PUNCT
admet-2766	330	15	modified	modify	VERB
admet-2766	330	16	spce	spce	NOUN
admet-2766	330	17	.	.	PUNCT
admet-2766	331	1	sensing	sense	VERB
admet-2766	331	2	and	and	CCONJ
admet-2766	331	3	biosensing	biosense	VERB
admet-2766	331	4	research	research	NOUN
admet-2766	331	5	47	47	NUM
admet-2766	331	6	(	(	PUNCT
admet-2766	331	7	2025	2025	NUM
admet-2766	331	8	)	)	PUNCT
admet-2766	331	9	100765	100765	NUM
admet-2766	331	10	.	.	PUNCT
admet-2766	332	1	https://doi.org/10.1016/j.sbsr.2025.100765	https://doi.org/10.1016/j.sbsr.2025.100765	PROPN
admet-2766	333	1	[	[	X
admet-2766	333	2	42	42	NUM
admet-2766	333	3	]	]	X
admet-2766	333	4	c.m	c.m	PROPN
admet-2766	333	5	.	.	PUNCT
admet-2766	334	1	dundas	dundas	PROPN
admet-2766	334	2	,	,	PUNCT
admet-2766	334	3	d.	d.	PROPN
admet-2766	334	4	demonte	demonte	PROPN
admet-2766	334	5	,	,	PUNCT
admet-2766	334	6	s.	s.	PROPN
admet-2766	334	7	park	park	PROPN
admet-2766	334	8	.	.	PUNCT
admet-2766	335	1	streptavidin	streptavidin	PROPN
admet-2766	335	2	-	-	PUNCT
admet-2766	335	3	biotin	biotin	NOUN
admet-2766	335	4	technology	technology	NOUN
admet-2766	335	5	:	:	PUNCT
admet-2766	335	6	improvements	improvement	NOUN
admet-2766	335	7	and	and	CCONJ
admet-2766	335	8	innovations	innovation	NOUN
admet-2766	335	9	in	in	ADP
admet-2766	335	10	chemical	chemical	ADJ
admet-2766	335	11	and	and	CCONJ
admet-2766	335	12	biological	biological	ADJ
admet-2766	335	13	applications	application	NOUN
admet-2766	335	14	.	.	PUNCT
admet-2766	336	1	applied	apply	VERB
admet-2766	336	2	microbiology	microbiology	NOUN
admet-2766	336	3	and	and	CCONJ
admet-2766	336	4	biotechnology	biotechnology	NOUN
admet-2766	336	5	97	97	NUM
admet-2766	336	6	(	(	PUNCT
admet-2766	336	7	2013	2013	NUM
admet-2766	336	8	)	)	PUNCT
admet-2766	336	9	.	.	PUNCT
admet-2766	337	1	9343	9343	NUM
admet-2766	337	2	-	-	SYM
admet-2766	337	3	9353	9353	NUM
admet-2766	337	4	.	.	PUNCT
admet-2766	338	1	https://doi.org/10.1007/s00253-013-5232-z	https://doi.org/10.1007/s00253-013-5232-z	NOUN
admet-2766	339	1	[	[	X
admet-2766	339	2	43	43	NUM
admet-2766	339	3	]	]	PUNCT
admet-2766	339	4	m.	m.	PROPN
admet-2766	339	5	drozd	drozd	PROPN
admet-2766	339	6	,	,	PUNCT
admet-2766	339	7	s.	s.	PROPN
admet-2766	339	8	karoń	karoń	PROPN
admet-2766	339	9	,	,	PUNCT
admet-2766	339	10	e.	e.	PROPN
admet-2766	339	11	malinowska	malinowska	PROPN
admet-2766	339	12	.	.	PUNCT
admet-2766	340	1	recent	recent	ADJ
admet-2766	340	2	advancements	advancement	NOUN
admet-2766	340	3	in	in	ADP
admet-2766	340	4	receptor	receptor	NOUN
admet-2766	340	5	layer	layer	NOUN
admet-2766	340	6	engineering	engineering	NOUN
admet-2766	340	7	for	for	ADP
admet-2766	340	8	applications	application	NOUN
admet-2766	340	9	in	in	ADP
admet-2766	340	10	spr	spr	ADV
admet-2766	340	11	-	-	PUNCT
admet-2766	340	12	based	base	VERB
admet-2766	340	13	immunodiagnostics	immunodiagnostic	NOUN
admet-2766	340	14	.	.	PUNCT
admet-2766	341	1	sensors	sensor	NOUN
admet-2766	341	2	21(11	21(11	NUM
admet-2766	341	3	)	)	PUNCT
admet-2766	341	4	(	(	PUNCT
admet-2766	341	5	2021	2021	NUM
admet-2766	341	6	)	)	PUNCT
admet-2766	341	7	3781	3781	NUM
admet-2766	341	8	.	.	PUNCT
admet-2766	342	1	https://doi.org/10.3390/s21113781	https://doi.org/10.3390/s21113781	NUM
admet-2766	343	1	[	[	X
admet-2766	343	2	44	44	NUM
admet-2766	343	3	]	]	PUNCT
admet-2766	343	4	f.	f.	PROPN
admet-2766	343	5	gao	gao	PROPN
admet-2766	343	6	,	,	PUNCT
admet-2766	343	7	g.	g.	PROPN
admet-2766	343	8	liu	liu	PROPN
admet-2766	343	9	,	,	PUNCT
admet-2766	343	10	y.	y.	PROPN
admet-2766	343	11	qiao	qiao	PROPN
admet-2766	343	12	,	,	PUNCT
admet-2766	343	13	x.	x.	PROPN
admet-2766	343	14	dong	dong	PROPN
admet-2766	343	15	,	,	PUNCT
admet-2766	343	16	l.	l.	PROPN
admet-2766	343	17	liu	liu	PROPN
admet-2766	343	18	.	.	PUNCT
admet-2766	344	1	streptavidin	streptavidin	PROPN
admet-2766	344	2	-	-	VERB
admet-2766	344	3	conjugated	conjugate	VERB
admet-2766	344	4	dna	dna	NOUN
admet-2766	344	5	for	for	ADP
admet-2766	344	6	the	the	DET
admet-2766	344	7	boronate	boronate	NOUN
admet-2766	344	8	affinity	affinity	NOUN
admet-2766	344	9	-	-	PUNCT
admet-2766	344	10	based	base	VERB
admet-2766	344	11	detection	detection	NOUN
admet-2766	344	12	of	of	ADP
admet-2766	344	13	poly(adp	poly(adp	NOUN
admet-2766	344	14	-	-	PUNCT
admet-2766	344	15	ribose	ribose	NOUN
admet-2766	344	16	)	)	PUNCT
admet-2766	344	17	polymerase-1	polymerase-1	NOUN
admet-2766	344	18	with	with	ADP
admet-2766	344	19	improved	improved	ADJ
admet-2766	344	20	sensitivity	sensitivity	NOUN
admet-2766	344	21	.	.	PUNCT
admet-2766	345	1	biosensors	biosensor	NOUN
admet-2766	345	2	13	13	NUM
admet-2766	345	3	(	(	PUNCT
admet-2766	345	4	2023	2023	NUM
admet-2766	345	5	)	)	PUNCT
admet-2766	345	6	723	723	NUM
admet-2766	345	7	.	.	PUNCT
admet-2766	346	1	https://doi.org/10.3390/bios13070723	https://doi.org/10.3390/bios13070723	PROPN
admet-2766	346	2	[	[	X
admet-2766	346	3	45	45	NUM
admet-2766	346	4	]	]	X
admet-2766	346	5	f.v	f.v	PROPN
admet-2766	346	6	.	.	PROPN
admet-2766	346	7	oberhaus	oberhaus	PROPN
admet-2766	346	8	,	,	PUNCT
admet-2766	346	9	d.	d.	PROPN
admet-2766	346	10	frense	frense	PROPN
admet-2766	346	11	,	,	PUNCT
admet-2766	346	12	d.	d.	PROPN
admet-2766	346	13	beckmann	beckmann	PROPN
admet-2766	346	14	.	.	PUNCT
admet-2766	347	1	immobilization	immobilization	NOUN
admet-2766	347	2	techniques	technique	NOUN
admet-2766	347	3	for	for	ADP
admet-2766	347	4	aptamers	aptamer	NOUN
admet-2766	347	5	on	on	ADP
admet-2766	347	6	gold	gold	NOUN
admet-2766	347	7	electrodes	electrode	NOUN
admet-2766	347	8	for	for	ADP
admet-2766	347	9	the	the	DET
admet-2766	347	10	electrochemical	electrochemical	ADJ
admet-2766	347	11	detection	detection	NOUN
admet-2766	347	12	of	of	ADP
admet-2766	347	13	proteins	protein	NOUN
admet-2766	347	14	:	:	PUNCT
admet-2766	347	15	a	a	DET
admet-2766	347	16	review	review	NOUN
admet-2766	347	17	.	.	PUNCT
admet-2766	348	1	biosensors	biosensor	NOUN
admet-2766	348	2	10	10	NUM
admet-2766	348	3	(	(	PUNCT
admet-2766	348	4	2020	2020	NUM
admet-2766	348	5	)	)	PUNCT
admet-2766	348	6	45	45	NUM
admet-2766	348	7	.	.	PUNCT
admet-2766	349	1	http://dx.doi.org/10.3390/bios10050045	http://dx.doi.org/10.3390/bios10050045	ADV
admet-2766	349	2	[	[	X
admet-2766	349	3	46	46	NUM
admet-2766	349	4	]	]	X
admet-2766	349	5	g.	g.	PROPN
admet-2766	349	6	ströhle	ströhle	PROPN
admet-2766	349	7	,	,	PUNCT
admet-2766	349	8	h.	h.	PROPN
admet-2766	349	9	li	li	PROPN
admet-2766	349	10	.	.	PROPN
admet-2766	349	11	comparison	comparison	NOUN
admet-2766	349	12	of	of	ADP
admet-2766	349	13	blocking	block	VERB
admet-2766	349	14	reagents	reagent	NOUN
admet-2766	349	15	for	for	ADP
admet-2766	349	16	antibody	antibody	NOUN
admet-2766	349	17	microarray‑based	microarray‑base	VERB
admet-2766	349	18	immunoassays	immunoassay	NOUN
admet-2766	349	19	on	on	ADP
admet-2766	349	20	glass	glass	NOUN
admet-2766	349	21	and	and	CCONJ
admet-2766	349	22	paper	paper	NOUN
admet-2766	349	23	membrane	membrane	NOUN
admet-2766	349	24	substrates	substrate	NOUN
admet-2766	349	25	.	.	PUNCT
admet-2766	350	1	analytical	analytical	ADJ
admet-2766	350	2	and	and	CCONJ
admet-2766	350	3	bioanalytical	bioanalytical	ADJ
admet-2766	350	4	chemistry	chemistry	NOUN
admet-2766	350	5	415	415	NUM
admet-2766	350	6	(	(	PUNCT
admet-2766	350	7	2023	2023	NUM
admet-2766	350	8	)	)	PUNCT
admet-2766	350	9	.	.	PUNCT
admet-2766	351	1	19671977	19671977	NUM
admet-2766	351	2	.	.	PUNCT
admet-2766	352	1	https://doi.org/10.1007/s00216-023-04614-w	https://doi.org/10.1007/s00216-023-04614-w	X
admet-2766	353	1	[	[	X
admet-2766	353	2	47	47	NUM
admet-2766	353	3	]	]	X
admet-2766	353	4	n.	n.	PROPN
admet-2766	353	5	chen	chen	PROPN
admet-2766	353	6	,	,	PUNCT
admet-2766	353	7	z.j	z.j	PROPN
admet-2766	353	8	.	.	PROPN
admet-2766	353	9	wu	wu	PROPN
admet-2766	353	10	,	,	PUNCT
admet-2766	353	11	h.c	h.c	PROPN
admet-2766	353	12	.	.	PUNCT
admet-2766	353	13	xu	xu	PROPN
admet-2766	353	14	.	.	PUNCT
admet-2766	353	15	ferrocene	ferrocene	NOUN
admet-2766	353	16	as	as	ADP
admet-2766	353	17	a	a	DET
admet-2766	353	18	redox	redox	ADJ
admet-2766	353	19	catalyst	catalyst	NOUN
admet-2766	353	20	for	for	ADP
admet-2766	353	21	organic	organic	ADJ
admet-2766	353	22	electrosynthesis	electrosynthesis	NOUN
admet-2766	353	23	.	.	PUNCT
admet-2766	354	1	israel	israel	PROPN
admet-2766	354	2	journal	journal	PROPN
admet-2766	354	3	of	of	ADP
admet-2766	354	4	chemistry	chemistry	NOUN
admet-2766	354	5	64	64	NUM
admet-2766	354	6	(	(	PUNCT
admet-2766	354	7	2023	2023	NUM
admet-2766	354	8	)	)	PUNCT
admet-2766	354	9	.	.	PUNCT
admet-2766	355	1	https://doi.org/10.1002/ijch.202300097	https://doi.org/10.1002/ijch.202300097	X
admet-2766	356	1	[	[	X
admet-2766	356	2	48	48	NUM
admet-2766	356	3	]	]	PUNCT
admet-2766	356	4	v.	v.	PRON
admet-2766	356	5	mekler	mekler	NOUN
admet-2766	356	6	,	,	PUNCT
admet-2766	356	7	l.	l.	PROPN
admet-2766	356	8	minakhin	minakhin	PROPN
admet-2766	356	9	,	,	PUNCT
admet-2766	356	10	k.	k.	PROPN
admet-2766	356	11	severinov	severinov	PROPN
admet-2766	356	12	.	.	PUNCT
admet-2766	357	1	mechanism	mechanism	NOUN
admet-2766	357	2	of	of	ADP
admet-2766	357	3	duplex	duplex	NOUN
admet-2766	357	4	dna	dna	NOUN
admet-2766	357	5	destabilization	destabilization	NOUN
admet-2766	357	6	by	by	ADP
admet-2766	357	7	rna	rna	NOUN
admet-2766	357	8	-	-	PUNCT
admet-2766	357	9	guided	guide	VERB
admet-2766	357	10	cas9	cas9	NOUN
admet-2766	357	11	nuclease	nuclease	NOUN
admet-2766	357	12	during	during	ADP
admet-2766	357	13	target	target	NOUN
admet-2766	357	14	interrogation	interrogation	NOUN
admet-2766	357	15	.	.	PUNCT
admet-2766	358	1	the	the	DET
admet-2766	358	2	proceedings	proceeding	NOUN
admet-2766	358	3	of	of	ADP
admet-2766	358	4	the	the	DET
admet-2766	358	5	national	national	PROPN
admet-2766	358	6	academy	academy	PROPN
admet-2766	358	7	of	of	ADP
admet-2766	358	8	sciences	sciences	PROPN
admet-2766	358	9	(	(	PUNCT
admet-2766	358	10	pnas	pnas	PROPN
admet-2766	358	11	)	)	PUNCT
admet-2766	358	12	114	114	NUM
admet-2766	358	13	(	(	PUNCT
admet-2766	358	14	2017	2017	NUM
admet-2766	358	15	)	)	PUNCT
admet-2766	358	16	5443	5443	NUM
admet-2766	358	17	-	-	SYM
admet-2766	358	18	5448	5448	NUM
admet-2766	358	19	.	.	PUNCT
admet-2766	358	20	https://doi.org/10.1073/pnas.1619926114	https://doi.org/10.1073/pnas.1619926114	X
admet-2766	359	1	[	[	X
admet-2766	359	2	49	49	NUM
admet-2766	359	3	]	]	PUNCT
admet-2766	359	4	s.	s.	PROPN
admet-2766	359	5	h.	h.	PROPN
admet-2766	359	6	sternberg	sternberg	PROPN
admet-2766	359	7	,	,	PUNCT
admet-2766	359	8	b.	b.	PROPN
admet-2766	359	9	lafrance	lafrance	PROPN
admet-2766	359	10	,	,	PUNCT
admet-2766	359	11	m.	m.	NOUN
admet-2766	359	12	kaplan	kaplan	PROPN
admet-2766	359	13	,	,	PUNCT
admet-2766	359	14	j.	j.	PROPN
admet-2766	359	15	a.	a.	PROPN
admet-2766	359	16	doudna	doudna	PROPN
admet-2766	359	17	.	.	PUNCT
admet-2766	360	1	conformational	conformational	ADJ
admet-2766	360	2	control	control	NOUN
admet-2766	360	3	of	of	ADP
admet-2766	360	4	dna	dna	PROPN
admet-2766	360	5	target	target	NOUN
admet-2766	360	6	cleavage	cleavage	NOUN
admet-2766	360	7	by	by	ADP
admet-2766	360	8	crispr	crispr	NOUN
admet-2766	360	9	-	-	PUNCT
admet-2766	360	10	cas9	cas9	NOUN
admet-2766	360	11	.	.	PUNCT
admet-2766	361	1	nature	nature	NOUN
admet-2766	361	2	527(2015	527(2015	NUM
admet-2766	361	3	)	)	PUNCT
admet-2766	361	4	110	110	NUM
admet-2766	361	5	113	113	NUM
admet-2766	361	6	.	.	PUNCT
admet-2766	362	1	https://doi.org/10.1038/nature15544	https://doi.org/10.1038/nature15544	PROPN
admet-2766	363	1	[	[	X
admet-2766	363	2	50	50	NUM
admet-2766	363	3	]	]	X
admet-2766	363	4	f.	f.	PROPN
admet-2766	363	5	jiang	jiang	PROPN
admet-2766	363	6	,	,	PUNCT
admet-2766	363	7	d.	d.	PROPN
admet-2766	363	8	w.	w.	PROPN
admet-2766	363	9	taylor	taylor	PROPN
admet-2766	363	10	,	,	PUNCT
admet-2766	363	11	j.	j.	PROPN
admet-2766	363	12	s.	s.	PROPN
admet-2766	363	13	chen	chen	PROPN
admet-2766	363	14	,	,	PUNCT
admet-2766	363	15	j.	j.	PROPN
admet-2766	363	16	e.	e.	PROPN
admet-2766	363	17	kornfeld	kornfeld	PROPN
admet-2766	363	18	,	,	PUNCT
admet-2766	363	19	k.	k.	PROPN
admet-2766	363	20	zhou	zhou	PROPN
admet-2766	363	21	,	,	PUNCT
admet-2766	363	22	a.	a.	PROPN
admet-2766	363	23	j.	j.	PROPN
admet-2766	363	24	thompson	thompson	PROPN
admet-2766	363	25	,	,	PUNCT
admet-2766	363	26	e.	e.	PROPN
admet-2766	363	27	nogales	nogales	PROPN
admet-2766	363	28	,	,	PUNCT
admet-2766	363	29	j.	j.	PROPN
admet-2766	363	30	a.	a.	PROPN
admet-2766	363	31	doudna	doudna	PROPN
admet-2766	363	32	.	.	PUNCT
admet-2766	364	1	structures	structure	NOUN
admet-2766	364	2	of	of	ADP
admet-2766	364	3	a	a	DET
admet-2766	364	4	crispr	crispr	ADJ
admet-2766	364	5	-	-	PUNCT
admet-2766	364	6	cas9	cas9	NOUN
admet-2766	364	7	r	r	NOUN
admet-2766	364	8	-	-	PUNCT
admet-2766	364	9	loop	loop	NOUN
admet-2766	364	10	complex	complex	NOUN
admet-2766	364	11	primed	prime	VERB
admet-2766	364	12	for	for	ADP
admet-2766	364	13	dna	dna	PROPN
admet-2766	364	14	cleavage	cleavage	NOUN
admet-2766	364	15	.	.	PUNCT
admet-2766	365	1	science	science	NOUN
admet-2766	365	2	351	351	NUM
admet-2766	365	3	(	(	PUNCT
admet-2766	365	4	2016	2016	NUM
admet-2766	365	5	)	)	PUNCT
admet-2766	365	6	867	867	NUM
admet-2766	365	7	-	-	SYM
admet-2766	365	8	871	871	NUM
admet-2766	365	9	.	.	PUNCT
admet-2766	366	1	https://doi.org/10.1126/science.aad8282	https://doi.org/10.1126/science.aad8282	PROPN
admet-2766	367	1	©	©	PROPN
admet-2766	367	2	2025	2025	NUM
admet-2766	367	3	by	by	ADP
admet-2766	367	4	the	the	DET
admet-2766	367	5	authors	author	NOUN
admet-2766	367	6	;	;	PUNCT
admet-2766	367	7	licensee	licensee	PROPN
admet-2766	367	8	iapc	iapc	PROPN
admet-2766	367	9	,	,	PUNCT
admet-2766	367	10	zagreb	zagreb	PROPN
admet-2766	367	11	,	,	PUNCT
admet-2766	367	12	croatia	croatia	PROPN
admet-2766	367	13	.	.	PUNCT
admet-2766	368	1	this	this	DET
admet-2766	368	2	article	article	NOUN
admet-2766	368	3	is	be	AUX
admet-2766	368	4	an	an	DET
admet-2766	368	5	open	open	ADJ
admet-2766	368	6	-	-	PUNCT
admet-2766	368	7	access	access	NOUN
admet-2766	368	8	article	article	NOUN
admet-2766	368	9	distributed	distribute	VERB
admet-2766	368	10	under	under	ADP
admet-2766	368	11	the	the	DET
admet-2766	368	12	terms	term	NOUN
admet-2766	368	13	and	and	CCONJ
admet-2766	368	14	conditions	condition	NOUN
admet-2766	368	15	of	of	ADP
admet-2766	368	16	the	the	DET
admet-2766	368	17	creative	creative	ADJ
admet-2766	368	18	commons	common	NOUN
admet-2766	368	19	attribution	attribution	NOUN
admet-2766	368	20	license	license	NOUN
admet-2766	368	21	(	(	PUNCT
admet-2766	368	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-2766	368	23	)	)	PUNCT
admet-2766	368	24	https://doi.org/10.5599/admet.2577	https://doi.org/10.5599/admet.2577	PART
admet-2766	368	25	https://doi.org/10.1039/d4nr02326a	https://doi.org/10.1039/d4nr02326a	PROPN
admet-2766	368	26	https://doi.org/10.1016/j.sbsr.2025.100765	https://doi.org/10.1016/j.sbsr.2025.100765	PROPN
admet-2766	368	27	https://doi.org/10.1007/s00253-013-5232-z	https://doi.org/10.1007/s00253-013-5232-z	NOUN
admet-2766	368	28	https://doi.org/10.3390/s21113781	https://doi.org/10.3390/s21113781	NUM
admet-2766	368	29	https://doi.org/10.3390/bios13070723	https://doi.org/10.3390/bios13070723	ADJ
admet-2766	368	30	http://dx.doi.org/10.3390/bios10050045	http://dx.doi.org/10.3390/bios10050045	ADJ
admet-2766	368	31	https://doi.org/10.1007/s00216-023-04614-w	https://doi.org/10.1007/s00216-023-04614-w	PROPN
admet-2766	368	32	https://doi.org/10.1002/ijch.202300097	https://doi.org/10.1002/ijch.202300097	PROPN
admet-2766	368	33	https://doi.org/10.1073/pnas.1619926114	https://doi.org/10.1073/pnas.1619926114	PROPN
admet-2766	368	34	https://doi.org/10.1038/nature15544	https://doi.org/10.1038/nature15544	PROPN
admet-2766	368	35	https://doi.org/10.1126/science.aad8282	https://doi.org/10.1126/science.aad8282	PROPN
admet-2766	368	36	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN