id	sid	tid	token	lemma	pos
admet-2859	1	1	comparison	comparison	NOUN
admet-2859	1	2	of	of	ADP
admet-2859	1	3	lipophilic	lipophilic	ADJ
admet-2859	1	4	and	and	CCONJ
admet-2859	1	5	size	size	NOUN
admet-2859	1	6	-	-	PUNCT
admet-2859	1	7	exclusion	exclusion	NOUN
admet-2859	1	8	membranes	membrane	NOUN
admet-2859	1	9	:	:	PUNCT
admet-2859	1	10	creating	create	VERB
admet-2859	1	11	sink	sink	NOUN
admet-2859	1	12	conditions	condition	NOUN
admet-2859	1	13	with	with	ADP
admet-2859	1	14	cyclodextrin	cyclodextrin	NOUN
admet-2859	1	15	doi	doi	NOUN
admet-2859	1	16	:	:	PUNCT
admet-2859	1	17	http://dx.doi.org/10.5599/admet.2859	http://dx.doi.org/10.5599/admet.2859	X
admet-2859	1	18	1	1	NUM
admet-2859	1	19	admet	admet	X
admet-2859	1	20	&	&	CCONJ
admet-2859	1	21	dmpk	dmpk	PROPN
admet-2859	1	22	13(5	13(5	NUM
admet-2859	1	23	)	)	PUNCT
admet-2859	1	24	(	(	PUNCT
admet-2859	1	25	2025	2025	NUM
admet-2859	1	26	)	)	PUNCT
admet-2859	1	27	2859	2859	NUM
admet-2859	1	28	;	;	PUNCT
admet-2859	1	29	doi	doi	NOUN
admet-2859	1	30	:	:	PUNCT
admet-2859	1	31	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	X
admet-2859	1	32	open	open	ADJ
admet-2859	1	33	access	access	NOUN
admet-2859	1	34	:	:	PUNCT
admet-2859	1	35	issn	issn	PROPN
admet-2859	1	36	:	:	PUNCT
admet-2859	1	37	1848	1848	NUM
admet-2859	1	38	-	-	SYM
admet-2859	1	39	7718	7718	NUM
admet-2859	1	40	http://www.pub.iapchem.org/ojs/index.ph-p/admet/index	http://www.pub.iapchem.org/ojs/index.ph-p/admet/index	PROPN
admet-2859	1	41	original	original	ADJ
admet-2859	1	42	scientific	scientific	ADJ
admet-2859	1	43	paper	paper	NOUN
admet-2859	1	44	comparison	comparison	NOUN
admet-2859	1	45	of	of	ADP
admet-2859	1	46	lipophilic	lipophilic	ADJ
admet-2859	1	47	and	and	CCONJ
admet-2859	1	48	size	size	NOUN
admet-2859	1	49	-	-	PUNCT
admet-2859	1	50	exclusion	exclusion	NOUN
admet-2859	1	51	membranes	membrane	NOUN
admet-2859	1	52	:	:	PUNCT
admet-2859	1	53	creating	create	VERB
admet-2859	1	54	sink	sink	NOUN
admet-2859	1	55	conditions	condition	NOUN
admet-2859	1	56	with	with	ADP
admet-2859	1	57	cyclodextrin	cyclodextrin	NOUN
admet-2859	1	58	petra	petra	PROPN
admet-2859	1	59	tőzsér1	tőzsér1	PROPN
admet-2859	1	60	,	,	PUNCT
admet-2859	1	61	szabina	szabina	PROPN
admet-2859	1	62	kádár1	kádár1	PROPN
admet-2859	1	63	,	,	PUNCT
admet-2859	1	64	edina	edina	PROPN
admet-2859	1	65	szabó1	szabó1	PROPN
admet-2859	1	66	,	,	PUNCT
admet-2859	1	67	hajnalka	hajnalka	PROPN
admet-2859	1	68	pataki1	pataki1	NOUN
admet-2859	1	69	,	,	PUNCT
admet-2859	1	70	péter	péter	NOUN
admet-2859	1	71	sóti2	sóti2	NOUN
admet-2859	1	72	,	,	PUNCT
admet-2859	1	73	péter	péter	NOUN
admet-2859	1	74	laczay2	laczay2	NOUN
admet-2859	1	75	,	,	PUNCT
admet-2859	1	76	györgy	györgy	PROPN
admet-2859	1	77	t.	t.	PROPN
admet-2859	1	78	balogh3,4,5	balogh3,4,5	NOUN
admet-2859	1	79	,	,	PUNCT
admet-2859	1	80	bálint	bálint	NOUN
admet-2859	1	81	sinkó6	sinkó6	PROPN
admet-2859	1	82	and	and	CCONJ
admet-2859	1	83	enikő	enikő	PROPN
admet-2859	1	84	borbás1	borbás1	PROPN
admet-2859	1	85	,	,	PUNCT
admet-2859	1	86	*	*	PROPN
admet-2859	1	87	1department	1department	NUM
admet-2859	1	88	of	of	ADP
admet-2859	1	89	organic	organic	ADJ
admet-2859	1	90	chemistry	chemistry	NOUN
admet-2859	1	91	and	and	CCONJ
admet-2859	1	92	technology	technology	NOUN
admet-2859	1	93	,	,	PUNCT
admet-2859	1	94	faculty	faculty	NOUN
admet-2859	1	95	of	of	ADP
admet-2859	1	96	chemical	chemical	ADJ
admet-2859	1	97	technology	technology	NOUN
admet-2859	1	98	and	and	CCONJ
admet-2859	1	99	biotechnology	biotechnology	NOUN
admet-2859	1	100	,	,	PUNCT
admet-2859	1	101	budapest	budapest	PROPN
admet-2859	1	102	university	university	PROPN
admet-2859	1	103	of	of	ADP
admet-2859	1	104	technology	technology	NOUN
admet-2859	1	105	and	and	CCONJ
admet-2859	1	106	economics	economic	NOUN
admet-2859	1	107	,	,	PUNCT
admet-2859	1	108	3	3	NUM
admet-2859	1	109	műegyetem	műegyetem	NOUN
admet-2859	1	110	quay	quay	NOUN
admet-2859	1	111	,	,	PUNCT
admet-2859	1	112	h-1111	h-1111	PROPN
admet-2859	1	113	,	,	PUNCT
admet-2859	1	114	budapest	budapest	NOUN
admet-2859	1	115	,	,	PUNCT
admet-2859	1	116	hungary	hungary	PROPN
admet-2859	1	117	2lavet	2lavet	NUM
admet-2859	1	118	pharmaceutical	pharmaceutical	PROPN
admet-2859	1	119	ltd	ltd	PROPN
admet-2859	1	120	.	.	PROPN
admet-2859	1	121	,	,	PUNCT
admet-2859	1	122	6	6	NUM
admet-2859	1	123	batthyány	batthyány	PROPN
admet-2859	1	124	street	street	PROPN
admet-2859	1	125	.	.	PUNCT
admet-2859	1	126	,	,	PUNCT
admet-2859	1	127	h-2143	h-2143	PROPN
admet-2859	1	128	,	,	PUNCT
admet-2859	1	129	kistarcsa	kistarcsa	NOUN
admet-2859	1	130	,	,	PUNCT
admet-2859	1	131	hungary	hungary	PROPN
admet-2859	1	132	3department	3department	NUM
admet-2859	1	133	of	of	ADP
admet-2859	1	134	pharmaceutical	pharmaceutical	ADJ
admet-2859	1	135	chemistry	chemistry	NOUN
admet-2859	1	136	,	,	PUNCT
admet-2859	1	137	faculty	faculty	NOUN
admet-2859	1	138	of	of	ADP
admet-2859	1	139	pharmaceutical	pharmaceutical	NOUN
admet-2859	1	140	sciences	science	NOUN
admet-2859	1	141	,	,	PUNCT
admet-2859	1	142	semmelweis	semmelweis	NOUN
admet-2859	1	143	university	university	NOUN
admet-2859	1	144	,	,	PUNCT
admet-2859	1	145	9	9	NUM
admet-2859	1	146	hőgyes	hőgyes	PROPN
admet-2859	1	147	endre	endre	PROPN
admet-2859	1	148	street	street	PROPN
admet-2859	1	149	.	.	PUNCT
admet-2859	1	150	,	,	PUNCT
admet-2859	1	151	h-1092	h-1092	PROPN
admet-2859	1	152	,	,	PUNCT
admet-2859	1	153	budapest	budapest	NOUN
admet-2859	1	154	,	,	PUNCT
admet-2859	1	155	hungary	hungary	PROPN
admet-2859	1	156	4center	4center	PROPN
admet-2859	1	157	for	for	ADP
admet-2859	1	158	pharmacology	pharmacology	NOUN
admet-2859	1	159	and	and	CCONJ
admet-2859	1	160	drug	drug	NOUN
admet-2859	1	161	research	research	PROPN
admet-2859	1	162	&	&	CCONJ
admet-2859	1	163	development	development	PROPN
admet-2859	1	164	,	,	PUNCT
admet-2859	1	165	semmelweis	semmelweis	NOUN
admet-2859	1	166	university	university	NOUN
admet-2859	1	167	,	,	PUNCT
admet-2859	1	168	26	26	NUM
admet-2859	1	169	üllői	üllői	PROPN
admet-2859	1	170	street	street	NOUN
admet-2859	1	171	.	.	PUNCT
admet-2859	1	172	,	,	PUNCT
admet-2859	2	1	h-1085	h-1085	PROPN
admet-2859	2	2	,	,	PUNCT
admet-2859	2	3	budapest	budapest	NOUN
admet-2859	2	4	,	,	PUNCT
admet-2859	2	5	hungary	hungary	PROPN
admet-2859	2	6	5department	5department	NUM
admet-2859	2	7	of	of	ADP
admet-2859	2	8	chemical	chemical	NOUN
admet-2859	2	9	and	and	CCONJ
admet-2859	2	10	environmental	environmental	ADJ
admet-2859	2	11	process	process	NOUN
admet-2859	2	12	engineering	engineering	NOUN
admet-2859	2	13	,	,	PUNCT
admet-2859	2	14	faculty	faculty	NOUN
admet-2859	2	15	of	of	ADP
admet-2859	2	16	chemical	chemical	ADJ
admet-2859	2	17	technology	technology	NOUN
admet-2859	2	18	and	and	CCONJ
admet-2859	2	19	biotechnology	biotechnology	NOUN
admet-2859	2	20	,	,	PUNCT
admet-2859	2	21	budapest	budapest	PROPN
admet-2859	2	22	university	university	PROPN
admet-2859	2	23	of	of	ADP
admet-2859	2	24	technology	technology	NOUN
admet-2859	2	25	and	and	CCONJ
admet-2859	2	26	economics	economic	NOUN
admet-2859	2	27	,	,	PUNCT
admet-2859	2	28	3	3	NUM
admet-2859	2	29	műegyetem	műegyetem	NOUN
admet-2859	2	30	quay	quay	NOUN
admet-2859	2	31	.	.	PUNCT
admet-2859	2	32	,	,	PUNCT
admet-2859	2	33	h-1111	h-1111	PROPN
admet-2859	2	34	,	,	PUNCT
admet-2859	2	35	budapest	budapest	PROPN
admet-2859	2	36	,	,	PUNCT
admet-2859	2	37	hungary	hungary	PROPN
admet-2859	2	38	6pion	6pion	NUM
admet-2859	2	39	inc	inc	PROPN
admet-2859	2	40	.	.	PROPN
admet-2859	2	41	,	,	PUNCT
admet-2859	2	42	billerica	billerica	PROPN
admet-2859	2	43	,	,	PUNCT
admet-2859	2	44	10	10	NUM
admet-2859	2	45	cook	cook	PROPN
admet-2859	2	46	street	street	PROPN
admet-2859	2	47	,	,	PUNCT
admet-2859	2	48	massachusetts	massachusetts	PROPN
admet-2859	2	49	01821	01821	NUM
admet-2859	2	50	,	,	PUNCT
admet-2859	2	51	usa	usa	PROPN
admet-2859	2	52	*	*	PUNCT
admet-2859	2	53	corresponding	correspond	VERB
admet-2859	2	54	author	author	NOUN
admet-2859	2	55	:	:	PUNCT
admet-2859	2	56	e	e	NOUN
admet-2859	2	57	-	-	NOUN
admet-2859	2	58	mail	mail	NOUN
admet-2859	2	59	:	:	PUNCT
admet-2859	2	60	eniko.jaksaneborbas@edu.bme.hu	eniko.jaksaneborbas@edu.bme.hu	ADJ
admet-2859	2	61	;	;	PUNCT
admet-2859	2	62	tel	tel	PROPN
admet-2859	2	63	.	.	PUNCT
admet-2859	2	64	:	:	PUNCT
admet-2859	2	65	+36	+36	NUM
admet-2859	2	66	-	-	SYM
admet-2859	2	67	307273966	307273966	NUM
admet-2859	2	68	;	;	PUNCT
admet-2859	2	69	fax	fax	NOUN
admet-2859	2	70	:	:	PUNCT
admet-2859	2	71	+36	+36	NUM
admet-2859	2	72	-	-	SYM
admet-2859	2	73	307273966	307273966	NUM
admet-2859	2	74	received	receive	VERB
admet-2859	2	75	:	:	PUNCT
admet-2859	2	76	june	june	PROPN
admet-2859	2	77	16	16	NUM
admet-2859	2	78	,	,	PUNCT
admet-2859	2	79	2025	2025	NUM
admet-2859	2	80	;	;	PUNCT
admet-2859	2	81	revised	revise	VERB
admet-2859	2	82	:	:	PUNCT
admet-2859	2	83	august	august	PROPN
admet-2859	2	84	15	15	NUM
admet-2859	2	85	,	,	PUNCT
admet-2859	2	86	2025	2025	NUM
admet-2859	2	87	;	;	PUNCT
admet-2859	2	88	published	publish	VERB
admet-2859	2	89	:	:	PUNCT
admet-2859	2	90	august	august	PROPN
admet-2859	2	91	27	27	NUM
admet-2859	2	92	,	,	PUNCT
admet-2859	2	93	2025	2025	NUM
admet-2859	2	94	abstract	abstract	ADJ
admet-2859	2	95	background	background	NOUN
admet-2859	2	96	and	and	CCONJ
admet-2859	2	97	purpose	purpose	NOUN
admet-2859	2	98	:	:	PUNCT
admet-2859	2	99	the	the	DET
admet-2859	2	100	effective	effective	ADJ
admet-2859	2	101	transport	transport	NOUN
admet-2859	2	102	of	of	ADP
admet-2859	2	103	an	an	DET
admet-2859	2	104	active	active	ADJ
admet-2859	2	105	pharmaceutical	pharmaceutical	ADJ
admet-2859	2	106	ingredient	ingredient	NOUN
admet-2859	2	107	across	across	ADP
admet-2859	2	108	various	various	ADJ
admet-2859	2	109	membrane	membrane	NOUN
admet-2859	2	110	systems	system	NOUN
admet-2859	2	111	is	be	AUX
admet-2859	2	112	critical	critical	ADJ
admet-2859	2	113	for	for	ADP
admet-2859	2	114	enhancing	enhance	VERB
admet-2859	2	115	its	its	PRON
admet-2859	2	116	bioavailability	bioavailability	NOUN
admet-2859	2	117	,	,	PUNCT
admet-2859	2	118	especially	especially	ADV
admet-2859	2	119	in	in	ADP
admet-2859	2	120	formulations	formulation	NOUN
admet-2859	2	121	involving	involve	VERB
admet-2859	2	122	solubilizing	solubilize	VERB
admet-2859	2	123	agents	agent	NOUN
admet-2859	2	124	.	.	PUNCT
admet-2859	3	1	this	this	DET
admet-2859	3	2	study	study	NOUN
admet-2859	3	3	aims	aim	VERB
admet-2859	3	4	to	to	PART
admet-2859	3	5	investigate	investigate	VERB
admet-2859	3	6	the	the	DET
admet-2859	3	7	permeability	permeability	NOUN
admet-2859	3	8	differences	difference	NOUN
admet-2859	3	9	of	of	ADP
admet-2859	3	10	carvedilol	carvedilol	NOUN
admet-2859	3	11	between	between	ADP
admet-2859	3	12	lipophilic	lipophilic	NOUN
admet-2859	3	13	(	(	PUNCT
admet-2859	3	14	organic	organic	ADJ
admet-2859	3	15	solvent	solvent	NOUN
admet-2859	3	16	)	)	PUNCT
admet-2859	3	17	and	and	CCONJ
admet-2859	3	18	size	size	NOUN
admet-2859	3	19	-	-	PUNCT
admet-2859	3	20	exclusion	exclusion	NOUN
admet-2859	3	21	membranes	membrane	NOUN
admet-2859	3	22	in	in	ADP
admet-2859	3	23	the	the	DET
admet-2859	3	24	presence	presence	NOUN
admet-2859	3	25	of	of	ADP
admet-2859	3	26	2	2	NUM
admet-2859	3	27	-	-	PUNCT
admet-2859	3	28	hydroxypropyl	hydroxypropyl	NOUN
admet-2859	3	29	-	-	PUNCT
admet-2859	3	30	beta	beta	NOUN
admet-2859	3	31	-	-	PUNCT
admet-2859	3	32	cyclodextrin	cyclodextrin	NOUN
admet-2859	3	33	in	in	ADP
admet-2859	3	34	just	just	ADV
admet-2859	3	35	the	the	DET
admet-2859	3	36	acceptor	acceptor	NOUN
admet-2859	3	37	compartment	compartment	NOUN
admet-2859	3	38	or	or	CCONJ
admet-2859	3	39	both	both	DET
admet-2859	3	40	sides	side	NOUN
admet-2859	3	41	of	of	ADP
admet-2859	3	42	the	the	DET
admet-2859	3	43	membrane	membrane	NOUN
admet-2859	3	44	using	use	VERB
admet-2859	3	45	in	in	ADP
admet-2859	3	46	vitro	vitro	X
admet-2859	3	47	side	side	NOUN
admet-2859	3	48	-	-	PUNCT
admet-2859	3	49	by	by	ADP
admet-2859	3	50	-	-	PUNCT
admet-2859	3	51	side	side	NOUN
admet-2859	3	52	diffusion	diffusion	NOUN
admet-2859	3	53	cell	cell	NOUN
admet-2859	3	54	assays	assay	NOUN
admet-2859	3	55	.	.	PUNCT
admet-2859	4	1	experimental	experimental	ADJ
admet-2859	4	2	approach	approach	NOUN
admet-2859	4	3	:	:	PUNCT
admet-2859	4	4	cyclodextrins	cyclodextrin	NOUN
admet-2859	4	5	(	(	PUNCT
admet-2859	4	6	cds	cds	PROPN
admet-2859	4	7	)	)	PUNCT
admet-2859	4	8	on	on	ADP
admet-2859	4	9	the	the	DET
admet-2859	4	10	acceptor	acceptor	NOUN
admet-2859	4	11	side	side	NOUN
admet-2859	4	12	significantly	significantly	ADV
admet-2859	4	13	improved	improve	VERB
admet-2859	4	14	flux	flux	NOUN
admet-2859	4	15	and	and	CCONJ
admet-2859	4	16	permeability	permeability	NOUN
admet-2859	4	17	for	for	ADP
admet-2859	4	18	the	the	DET
admet-2859	4	19	lipophilic	lipophilic	ADJ
admet-2859	4	20	membrane	membrane	NOUN
admet-2859	4	21	.	.	PUNCT
admet-2859	5	1	in	in	ADP
admet-2859	5	2	contrast	contrast	NOUN
admet-2859	5	3	,	,	PUNCT
admet-2859	5	4	with	with	ADP
admet-2859	5	5	size	size	NOUN
admet-2859	5	6	-	-	PUNCT
admet-2859	5	7	exclusion	exclusion	NOUN
admet-2859	5	8	membranes	membrane	NOUN
admet-2859	5	9	that	that	PRON
admet-2859	5	10	allow	allow	VERB
admet-2859	5	11	the	the	DET
admet-2859	5	12	permeation	permeation	NOUN
admet-2859	5	13	of	of	ADP
admet-2859	5	14	cds	cd	NOUN
admet-2859	5	15	and	and	CCONJ
admet-2859	5	16	their	their	PRON
admet-2859	5	17	complexes	complex	NOUN
admet-2859	5	18	,	,	PUNCT
admet-2859	5	19	the	the	DET
admet-2859	5	20	benefits	benefit	NOUN
admet-2859	5	21	of	of	ADP
admet-2859	5	22	sink	sink	NOUN
admet-2859	5	23	conditions	condition	NOUN
admet-2859	5	24	were	be	AUX
admet-2859	5	25	completely	completely	ADV
admet-2859	5	26	diminished	diminish	VERB
admet-2859	5	27	.	.	PUNCT
admet-2859	6	1	when	when	SCONJ
admet-2859	6	2	the	the	DET
admet-2859	6	3	same	same	ADJ
admet-2859	6	4	amount	amount	NOUN
admet-2859	6	5	of	of	ADP
admet-2859	6	6	cd	cd	PROPN
admet-2859	6	7	was	be	AUX
admet-2859	6	8	introduced	introduce	VERB
admet-2859	6	9	on	on	ADP
admet-2859	6	10	both	both	DET
admet-2859	6	11	sides	side	NOUN
admet-2859	6	12	,	,	PUNCT
admet-2859	6	13	the	the	DET
admet-2859	6	14	negative	negative	ADJ
admet-2859	6	15	effect	effect	NOUN
admet-2859	6	16	of	of	ADP
admet-2859	6	17	cd	cd	PROPN
admet-2859	6	18	on	on	ADP
admet-2859	6	19	the	the	DET
admet-2859	6	20	donor	donor	NOUN
admet-2859	6	21	side	side	NOUN
admet-2859	6	22	surpassed	surpass	VERB
admet-2859	6	23	the	the	DET
admet-2859	6	24	positive	positive	ADJ
admet-2859	6	25	sink	sink	NOUN
admet-2859	6	26	effects	effect	NOUN
admet-2859	6	27	on	on	ADP
admet-2859	6	28	the	the	DET
admet-2859	6	29	acceptor	acceptor	NOUN
admet-2859	6	30	side	side	NOUN
admet-2859	6	31	,	,	PUNCT
admet-2859	6	32	resulting	result	VERB
admet-2859	6	33	in	in	ADP
admet-2859	6	34	reduced	reduce	VERB
admet-2859	6	35	flux	flux	NOUN
admet-2859	6	36	and	and	CCONJ
admet-2859	6	37	permeability	permeability	NOUN
admet-2859	6	38	across	across	ADP
admet-2859	6	39	all	all	DET
admet-2859	6	40	membrane	membrane	NOUN
admet-2859	6	41	types	type	NOUN
admet-2859	6	42	.	.	PUNCT
admet-2859	7	1	key	key	ADJ
admet-2859	7	2	results	result	NOUN
admet-2859	7	3	:	:	PUNCT
admet-2859	7	4	a	a	DET
admet-2859	7	5	novel	novel	ADJ
admet-2859	7	6	aspect	aspect	NOUN
admet-2859	7	7	of	of	ADP
admet-2859	7	8	this	this	DET
admet-2859	7	9	work	work	NOUN
admet-2859	7	10	is	be	AUX
admet-2859	7	11	the	the	DET
admet-2859	7	12	assessment	assessment	NOUN
admet-2859	7	13	of	of	ADP
admet-2859	7	14	the	the	DET
admet-2859	7	15	applicability	applicability	NOUN
admet-2859	7	16	of	of	ADP
admet-2859	7	17	a	a	DET
admet-2859	7	18	previously	previously	ADV
admet-2859	7	19	described	describe	VERB
admet-2859	7	20	general	general	ADJ
admet-2859	7	21	mathematical	mathematical	ADJ
admet-2859	7	22	equation	equation	NOUN
admet-2859	7	23	for	for	ADP
admet-2859	7	24	sink	sink	NOUN
admet-2859	7	25	conditions	condition	NOUN
admet-2859	7	26	.	.	PUNCT
admet-2859	8	1	findings	finding	NOUN
admet-2859	8	2	indicated	indicate	VERB
admet-2859	8	3	that	that	SCONJ
admet-2859	8	4	the	the	DET
admet-2859	8	5	supersaturation	supersaturation	NOUN
admet-2859	8	6	ratio	ratio	NOUN
admet-2859	8	7	between	between	ADP
admet-2859	8	8	donor	donor	NOUN
admet-2859	8	9	and	and	CCONJ
admet-2859	8	10	acceptor	acceptor	NOUN
admet-2859	8	11	compartments	compartment	NOUN
admet-2859	8	12	serves	serve	VERB
admet-2859	8	13	as	as	ADP
admet-2859	8	14	the	the	DET
admet-2859	8	15	primary	primary	ADJ
admet-2859	8	16	driving	driving	NOUN
admet-2859	8	17	force	force	NOUN
admet-2859	8	18	of	of	ADP
admet-2859	8	19	the	the	DET
admet-2859	8	20	membrane	membrane	NOUN
admet-2859	8	21	transport	transport	NOUN
admet-2859	8	22	.	.	PUNCT
admet-2859	9	1	for	for	ADP
admet-2859	9	2	the	the	DET
admet-2859	9	3	lipophilic	lipophilic	ADJ
admet-2859	9	4	membrane	membrane	NOUN
admet-2859	9	5	,	,	PUNCT
admet-2859	9	6	cds	cd	NOUN
admet-2859	9	7	on	on	ADP
admet-2859	9	8	the	the	DET
admet-2859	9	9	acceptor	acceptor	NOUN
admet-2859	9	10	side	side	NOUN
admet-2859	9	11	not	not	PART
admet-2859	9	12	only	only	ADV
admet-2859	9	13	influenced	influence	VERB
admet-2859	9	14	the	the	DET
admet-2859	9	15	driving	drive	VERB
admet-2859	9	16	force	force	NOUN
admet-2859	9	17	of	of	ADP
admet-2859	9	18	the	the	DET
admet-2859	9	19	transport	transport	NOUN
admet-2859	9	20	by	by	ADP
admet-2859	9	21	enhancing	enhance	VERB
admet-2859	9	22	the	the	DET
admet-2859	9	23	solubility	solubility	NOUN
admet-2859	9	24	of	of	ADP
admet-2859	9	25	carvedilol	carvedilol	NOUN
admet-2859	9	26	in	in	ADP
admet-2859	9	27	the	the	DET
admet-2859	9	28	acceptor	acceptor	NOUN
admet-2859	9	29	compartment	compartment	NOUN
admet-2859	9	30	but	but	CCONJ
admet-2859	9	31	also	also	ADV
admet-2859	9	32	altered	alter	VERB
admet-2859	9	33	the	the	DET
admet-2859	9	34	proportionality	proportionality	NOUN
admet-2859	9	35	coefficient	coefficient	NOUN
admet-2859	9	36	,	,	PUNCT
admet-2859	9	37	hence	hence	ADV
admet-2859	9	38	modifying	modify	VERB
admet-2859	9	39	the	the	DET
admet-2859	9	40	apparent	apparent	ADJ
admet-2859	9	41	thickness	thickness	NOUN
admet-2859	9	42	of	of	ADP
admet-2859	9	43	the	the	DET
admet-2859	9	44	unstirred	unstirred	ADJ
admet-2859	9	45	water	water	NOUN
admet-2859	9	46	layer	layer	NOUN
admet-2859	9	47	.	.	PUNCT
admet-2859	10	1	the	the	DET
admet-2859	10	2	impact	impact	NOUN
admet-2859	10	3	was	be	AUX
admet-2859	10	4	not	not	PART
admet-2859	10	5	observed	observe	VERB
admet-2859	10	6	with	with	ADP
admet-2859	10	7	size	size	NOUN
admet-2859	10	8	-	-	PUNCT
admet-2859	10	9	exclusion	exclusion	NOUN
admet-2859	10	10	membranes	membrane	NOUN
admet-2859	10	11	.	.	PUNCT
admet-2859	11	1	the	the	DET
admet-2859	11	2	applicability	applicability	NOUN
admet-2859	11	3	of	of	ADP
admet-2859	11	4	the	the	DET
admet-2859	11	5	mathematical	mathematical	ADJ
admet-2859	11	6	model	model	NOUN
admet-2859	11	7	was	be	AUX
admet-2859	11	8	additionally	additionally	ADV
admet-2859	11	9	evaluated	evaluate	VERB
admet-2859	11	10	for	for	ADP
admet-2859	11	11	cd	cd	PROPN
admet-2859	11	12	placed	place	VERB
admet-2859	11	13	on	on	ADP
admet-2859	11	14	both	both	DET
admet-2859	11	15	sides	side	NOUN
admet-2859	11	16	of	of	ADP
admet-2859	11	17	the	the	DET
admet-2859	11	18	membrane	membrane	NOUN
admet-2859	11	19	.	.	PUNCT
admet-2859	12	1	conclusion	conclusion	NOUN
admet-2859	12	2	:	:	PUNCT
admet-2859	12	3	the	the	DET
admet-2859	12	4	model	model	NOUN
admet-2859	12	5	effectively	effectively	ADV
admet-2859	12	6	describes	describe	VERB
admet-2859	12	7	the	the	DET
admet-2859	12	8	impact	impact	NOUN
admet-2859	12	9	of	of	ADP
admet-2859	12	10	cd	cd	PROPN
admet-2859	12	11	placed	place	VERB
admet-2859	12	12	on	on	ADP
admet-2859	12	13	the	the	DET
admet-2859	12	14	donor	donor	NOUN
admet-2859	12	15	side	side	NOUN
admet-2859	12	16	when	when	SCONJ
admet-2859	12	17	the	the	DET
admet-2859	12	18	solid	solid	ADJ
admet-2859	12	19	membrane	membrane	NOUN
admet-2859	12	20	permits	permit	VERB
admet-2859	12	21	only	only	ADV
admet-2859	12	22	the	the	DET
admet-2859	12	23	drug	drug	NOUN
admet-2859	12	24	’s	’s	PART
admet-2859	12	25	permeation	permeation	NOUN
admet-2859	12	26	,	,	PUNCT
admet-2859	12	27	as	as	ADP
admet-2859	12	28	in	in	ADP
admet-2859	12	29	the	the	DET
admet-2859	12	30	case	case	NOUN
admet-2859	12	31	of	of	ADP
admet-2859	12	32	a	a	DET
admet-2859	12	33	lipophilic	lipophilic	ADJ
admet-2859	12	34	membrane	membrane	NOUN
admet-2859	12	35	,	,	PUNCT
admet-2859	12	36	where	where	SCONJ
admet-2859	12	37	the	the	DET
admet-2859	12	38	solubilizing	solubilizing	NOUN
admet-2859	12	39	additive	additive	NOUN
admet-2859	12	40	can	can	AUX
admet-2859	12	41	not	not	PART
admet-2859	12	42	pass	pass	VERB
admet-2859	12	43	through	through	ADV
admet-2859	12	44	.	.	PUNCT
admet-2859	13	1	it	it	PRON
admet-2859	13	2	is	be	AUX
admet-2859	13	3	also	also	ADV
admet-2859	13	4	applicable	applicable	ADJ
admet-2859	13	5	when	when	SCONJ
admet-2859	13	6	the	the	DET
admet-2859	13	7	solubilizing	solubilize	VERB
admet-2859	13	8	additive	additive	NOUN
admet-2859	13	9	permeates	permeate	VERB
admet-2859	13	10	slowly	slowly	ADV
admet-2859	13	11	and	and	CCONJ
admet-2859	13	12	has	have	VERB
admet-2859	13	13	minimal	minimal	ADJ
admet-2859	13	14	influence	influence	NOUN
admet-2859	13	15	on	on	ADP
admet-2859	13	16	transport	transport	NOUN
admet-2859	13	17	,	,	PUNCT
admet-2859	13	18	such	such	ADJ
admet-2859	13	19	as	as	ADP
admet-2859	13	20	with	with	ADP
admet-2859	13	21	a	a	DET
admet-2859	13	22	sizeexclusion	sizeexclusion	NOUN
admet-2859	13	23	membrane	membrane	NOUN
admet-2859	13	24	with	with	ADP
admet-2859	13	25	a	a	DET
admet-2859	13	26	1	1	NUM
admet-2859	13	27	kda	kda	NOUN
admet-2859	13	28	molecular	molecular	ADJ
admet-2859	13	29	weight	weight	NOUN
admet-2859	13	30	cut	cut	NOUN
admet-2859	13	31	-	-	PUNCT
admet-2859	13	32	off	off	NOUN
admet-2859	13	33	.	.	PUNCT
admet-2859	14	1	the	the	DET
admet-2859	14	2	model	model	NOUN
admet-2859	14	3	remains	remain	VERB
admet-2859	14	4	suitable	suitable	ADJ
admet-2859	14	5	if	if	SCONJ
admet-2859	14	6	the	the	DET
admet-2859	14	7	additive	additive	NOUN
admet-2859	14	8	is	be	AUX
admet-2859	14	9	small	small	ADJ
admet-2859	14	10	enough	enough	ADV
admet-2859	14	11	in	in	ADP
admet-2859	14	12	hydrodynamic	hydrodynamic	ADJ
admet-2859	14	13	size	size	NOUN
admet-2859	14	14	to	to	PART
admet-2859	14	15	permeate	permeate	VERB
admet-2859	14	16	the	the	DET
admet-2859	14	17	membrane	membrane	NOUN
admet-2859	14	18	,	,	PUNCT
admet-2859	14	19	but	but	CCONJ
admet-2859	14	20	no	no	DET
admet-2859	14	21	concentration	concentration	NOUN
admet-2859	14	22	gradient	gradient	NOUN
admet-2859	14	23	exists	exist	VERB
admet-2859	14	24	to	to	PART
admet-2859	14	25	drive	drive	VERB
admet-2859	14	26	its	its	PRON
admet-2859	14	27	transport	transport	NOUN
admet-2859	14	28	,	,	PUNCT
admet-2859	14	29	for	for	ADP
admet-2859	14	30	example	example	NOUN
admet-2859	14	31	,	,	PUNCT
admet-2859	14	32	with	with	ADP
admet-2859	14	33	a	a	DET
admet-2859	14	34	6	6	NUM
admet-2859	14	35	kda	kda	NOUN
admet-2859	14	36	size	size	NOUN
admet-2859	14	37	-	-	PUNCT
admet-2859	14	38	exclusion	exclusion	NOUN
admet-2859	14	39	membrane	membrane	NOUN
admet-2859	14	40	containing	contain	VERB
admet-2859	14	41	the	the	DET
admet-2859	14	42	same	same	ADJ
admet-2859	14	43	cd	cd	NOUN
admet-2859	14	44	concentration	concentration	NOUN
admet-2859	14	45	on	on	ADP
admet-2859	14	46	both	both	DET
admet-2859	14	47	sides	side	NOUN
admet-2859	14	48	of	of	ADP
admet-2859	14	49	the	the	DET
admet-2859	14	50	membrane	membrane	NOUN
admet-2859	14	51	.	.	PUNCT
admet-2859	15	1	©	©	PROPN
admet-2859	15	2	2025	2025	NUM
admet-2859	15	3	by	by	ADP
admet-2859	15	4	the	the	DET
admet-2859	15	5	authors	author	NOUN
admet-2859	15	6	.	.	PUNCT
admet-2859	16	1	this	this	DET
admet-2859	16	2	article	article	NOUN
admet-2859	16	3	is	be	AUX
admet-2859	16	4	an	an	DET
admet-2859	16	5	open	open	ADJ
admet-2859	16	6	-	-	PUNCT
admet-2859	16	7	access	access	NOUN
admet-2859	16	8	article	article	NOUN
admet-2859	16	9	distributed	distribute	VERB
admet-2859	16	10	under	under	ADP
admet-2859	16	11	the	the	DET
admet-2859	16	12	terms	term	NOUN
admet-2859	16	13	and	and	CCONJ
admet-2859	16	14	conditions	condition	NOUN
admet-2859	16	15	of	of	ADP
admet-2859	16	16	the	the	DET
admet-2859	16	17	creative	creative	ADJ
admet-2859	16	18	commons	common	NOUN
admet-2859	16	19	attribution	attribution	NOUN
admet-2859	16	20	license	license	NOUN
admet-2859	16	21	(	(	PUNCT
admet-2859	16	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2859	16	23	)	)	PUNCT
admet-2859	16	24	.	.	PUNCT
admet-2859	17	1	http://dx.doi.org/10.5599/admet.2859	http://dx.doi.org/10.5599/admet.2859	X
admet-2859	18	1	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	PROPN
admet-2859	18	2	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-2859	18	3	mailto:eniko.jaksaneborbas@edu.bme.hu	mailto:eniko.jaksaneborbas@edu.bme.hu	PROPN
admet-2859	18	4	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-2859	18	5	p.	p.	PROPN
admet-2859	18	6	tőzsér	tőzsér	PROPN
admet-2859	19	1	et	et	PROPN
admet-2859	19	2	al	al	PROPN
admet-2859	19	3	.	.	PROPN
admet-2859	19	4	admet	admet	PROPN
admet-2859	19	5	&	&	CCONJ
admet-2859	19	6	dmpk	dmpk	PROPN
admet-2859	19	7	13(5	13(5	NUM
admet-2859	19	8	)	)	PUNCT
admet-2859	19	9	(	(	PUNCT
admet-2859	19	10	2025	2025	NUM
admet-2859	19	11	)	)	PUNCT
admet-2859	19	12	2859	2859	NUM
admet-2859	19	13	2	2	NUM
admet-2859	19	14	keywords	keyword	NOUN
admet-2859	19	15	unstirred	unstirred	ADJ
admet-2859	19	16	water	water	NOUN
admet-2859	19	17	layer	layer	NOUN
admet-2859	19	18	;	;	PUNCT
admet-2859	19	19	flux	flux	NOUN
admet-2859	19	20	;	;	PUNCT
admet-2859	19	21	solubility	solubility	NOUN
admet-2859	19	22	;	;	PUNCT
admet-2859	19	23	supersaturation	supersaturation	NOUN
admet-2859	19	24	ratio	ratio	NOUN
admet-2859	19	25	;	;	PUNCT
admet-2859	19	26	carvedilol	carvedilol	NOUN
admet-2859	19	27	introduction	introduction	NOUN
admet-2859	19	28	this	this	DET
admet-2859	19	29	study	study	NOUN
admet-2859	19	30	builds	build	VERB
admet-2859	19	31	upon	upon	SCONJ
admet-2859	19	32	our	our	PRON
admet-2859	19	33	previous	previous	ADJ
admet-2859	19	34	research	research	NOUN
admet-2859	19	35	[	[	X
admet-2859	19	36	1	1	NUM
admet-2859	19	37	]	]	PUNCT
admet-2859	19	38	,	,	PUNCT
admet-2859	19	39	which	which	PRON
admet-2859	19	40	investigated	investigate	VERB
admet-2859	19	41	the	the	DET
admet-2859	19	42	flux	flux	NOUN
admet-2859	19	43	differences	difference	NOUN
admet-2859	19	44	between	between	ADP
admet-2859	19	45	lipophilic	lipophilic	NOUN
admet-2859	19	46	and	and	CCONJ
admet-2859	19	47	size	size	NOUN
admet-2859	19	48	-	-	PUNCT
admet-2859	19	49	exclusion	exclusion	NOUN
admet-2859	19	50	membranes	membrane	NOUN
admet-2859	19	51	in	in	ADP
admet-2859	19	52	the	the	DET
admet-2859	19	53	presence	presence	NOUN
admet-2859	19	54	of	of	ADP
admet-2859	19	55	2	2	NUM
admet-2859	19	56	-	-	PUNCT
admet-2859	19	57	hydroxypropyl	hydroxypropyl	NOUN
admet-2859	19	58	-	-	PUNCT
admet-2859	19	59	beta	beta	NOUN
admet-2859	19	60	-	-	PUNCT
admet-2859	19	61	cyclodextrin	cyclodextrin	NOUN
admet-2859	19	62	(	(	PUNCT
admet-2859	19	63	hp	hp	PROPN
admet-2859	19	64	-	-	PUNCT
admet-2859	19	65	β	β	NOUN
admet-2859	19	66	-	-	NOUN
admet-2859	19	67	cd	cd	NOUN
admet-2859	19	68	)	)	PUNCT
admet-2859	19	69	,	,	PUNCT
admet-2859	19	70	focusing	focus	VERB
admet-2859	19	71	on	on	ADP
admet-2859	19	72	the	the	DET
admet-2859	19	73	impact	impact	NOUN
admet-2859	19	74	of	of	ADP
admet-2859	19	75	stirring	stirring	NOUN
admet-2859	19	76	and	and	CCONJ
admet-2859	19	77	the	the	DET
admet-2859	19	78	addition	addition	NOUN
admet-2859	19	79	of	of	ADP
admet-2859	19	80	solubilizing	solubilize	VERB
admet-2859	19	81	agents	agent	NOUN
admet-2859	19	82	in	in	ADP
admet-2859	19	83	the	the	DET
admet-2859	19	84	donor	donor	NOUN
admet-2859	19	85	compartment	compartment	NOUN
admet-2859	19	86	.	.	PUNCT
admet-2859	20	1	however	however	ADV
admet-2859	20	2	,	,	PUNCT
admet-2859	20	3	it	it	PRON
admet-2859	20	4	primarily	primarily	ADV
admet-2859	20	5	examined	examine	VERB
admet-2859	20	6	cases	case	NOUN
admet-2859	20	7	where	where	SCONJ
admet-2859	20	8	hp	hp	NOUN
admet-2859	20	9	-	-	PUNCT
admet-2859	20	10	β	β	NOUN
admet-2859	20	11	-	-	NOUN
admet-2859	20	12	cd	cd	PROPN
admet-2859	20	13	was	be	AUX
admet-2859	20	14	added	add	VERB
admet-2859	20	15	to	to	ADP
admet-2859	20	16	the	the	DET
admet-2859	20	17	donor	donor	NOUN
admet-2859	20	18	side	side	NOUN
admet-2859	20	19	,	,	PUNCT
admet-2859	20	20	leaving	leave	VERB
admet-2859	20	21	open	open	ADJ
admet-2859	20	22	the	the	DET
admet-2859	20	23	question	question	NOUN
admet-2859	20	24	of	of	ADP
admet-2859	20	25	how	how	SCONJ
admet-2859	20	26	permeability	permeability	NOUN
admet-2859	20	27	and	and	CCONJ
admet-2859	20	28	the	the	DET
admet-2859	20	29	driving	drive	VERB
admet-2859	20	30	force	force	NOUN
admet-2859	20	31	of	of	ADP
admet-2859	20	32	membrane	membrane	NOUN
admet-2859	20	33	transport	transport	NOUN
admet-2859	20	34	change	change	NOUN
admet-2859	20	35	when	when	SCONJ
admet-2859	20	36	hp	hp	ADJ
admet-2859	20	37	-	-	PUNCT
admet-2859	20	38	β	β	NOUN
admet-2859	20	39	-	-	NOUN
admet-2859	20	40	cd	cd	PROPN
admet-2859	20	41	is	be	AUX
admet-2859	20	42	placed	place	VERB
admet-2859	20	43	in	in	ADP
admet-2859	20	44	the	the	DET
admet-2859	20	45	acceptor	acceptor	NOUN
admet-2859	20	46	compartment	compartment	NOUN
admet-2859	20	47	or	or	CCONJ
admet-2859	20	48	in	in	ADP
admet-2859	20	49	both	both	DET
admet-2859	20	50	compartments	compartment	NOUN
admet-2859	20	51	simultaneously	simultaneously	ADV
admet-2859	20	52	.	.	PUNCT
admet-2859	21	1	hp	hp	PROPN
admet-2859	21	2	-	-	PUNCT
admet-2859	21	3	β	β	NOUN
admet-2859	21	4	-	-	NOUN
admet-2859	21	5	cd	cd	NOUN
admet-2859	21	6	is	be	AUX
admet-2859	21	7	frequently	frequently	ADV
admet-2859	21	8	used	use	VERB
admet-2859	21	9	not	not	PART
admet-2859	21	10	only	only	ADV
admet-2859	21	11	as	as	ADP
admet-2859	21	12	a	a	DET
admet-2859	21	13	formulation	formulation	NOUN
admet-2859	21	14	additive	additive	NOUN
admet-2859	21	15	but	but	CCONJ
admet-2859	21	16	also	also	ADV
admet-2859	21	17	in	in	ADP
admet-2859	21	18	the	the	DET
admet-2859	21	19	acceptor	acceptor	NOUN
admet-2859	21	20	medium	medium	NOUN
admet-2859	21	21	to	to	PART
admet-2859	21	22	provide	provide	VERB
admet-2859	21	23	sink	sink	NOUN
admet-2859	21	24	conditions	condition	NOUN
admet-2859	22	1	[	[	X
admet-2859	22	2	2	2	NUM
admet-2859	22	3	-	-	SYM
admet-2859	22	4	6	6	NUM
admet-2859	22	5	]	]	PUNCT
admet-2859	22	6	in	in	ADP
admet-2859	22	7	dissolution	dissolution	NOUN
admet-2859	22	8	-	-	PUNCT
admet-2859	22	9	permeation	permeation	NOUN
admet-2859	22	10	testing	testing	NOUN
admet-2859	22	11	.	.	PUNCT
admet-2859	23	1	even	even	ADV
admet-2859	23	2	in	in	ADP
admet-2859	23	3	this	this	DET
admet-2859	23	4	case	case	NOUN
admet-2859	23	5	,	,	PUNCT
admet-2859	23	6	hp	hp	PROPN
admet-2859	23	7	-	-	PUNCT
admet-2859	23	8	β	β	NOUN
admet-2859	23	9	-	-	ADJ
admet-2859	23	10	cd	cd	ADJ
admet-2859	23	11	functions	function	NOUN
admet-2859	23	12	by	by	ADP
admet-2859	23	13	forming	form	VERB
admet-2859	23	14	inclusion	inclusion	NOUN
admet-2859	23	15	complexes	complex	NOUN
admet-2859	23	16	with	with	ADP
admet-2859	23	17	the	the	DET
admet-2859	23	18	drug	drug	NOUN
admet-2859	23	19	,	,	PUNCT
admet-2859	23	20	thus	thus	ADV
admet-2859	23	21	increasing	increase	VERB
admet-2859	23	22	the	the	DET
admet-2859	23	23	aqueous	aqueous	ADJ
admet-2859	23	24	solubility	solubility	NOUN
admet-2859	23	25	and	and	CCONJ
admet-2859	23	26	preserving	preserve	VERB
admet-2859	23	27	a	a	DET
admet-2859	23	28	consistent	consistent	ADJ
admet-2859	23	29	concentration	concentration	NOUN
admet-2859	23	30	gradient	gradient	NOUN
admet-2859	23	31	between	between	ADP
admet-2859	23	32	the	the	DET
admet-2859	23	33	donor	donor	NOUN
admet-2859	23	34	and	and	CCONJ
admet-2859	23	35	acceptor	acceptor	NOUN
admet-2859	23	36	sides	side	NOUN
admet-2859	23	37	.	.	PUNCT
admet-2859	24	1	the	the	DET
admet-2859	24	2	concept	concept	NOUN
admet-2859	24	3	of	of	ADP
admet-2859	24	4	sink	sink	NOUN
admet-2859	24	5	condition	condition	NOUN
admet-2859	24	6	is	be	AUX
admet-2859	24	7	fundamental	fundamental	ADJ
admet-2859	24	8	in	in	ADP
admet-2859	24	9	the	the	DET
admet-2859	24	10	field	field	NOUN
admet-2859	24	11	of	of	ADP
admet-2859	24	12	drug	drug	NOUN
admet-2859	24	13	dissolution	dissolution	NOUN
admet-2859	24	14	and	and	CCONJ
admet-2859	24	15	permeation	permeation	NOUN
admet-2859	24	16	studies	study	NOUN
admet-2859	24	17	.	.	PUNCT
admet-2859	25	1	sink	sink	PROPN
admet-2859	25	2	conditions	condition	NOUN
admet-2859	25	3	denote	denote	VERB
admet-2859	25	4	a	a	DET
admet-2859	25	5	state	state	NOUN
admet-2859	25	6	in	in	ADP
admet-2859	25	7	which	which	PRON
admet-2859	25	8	the	the	DET
admet-2859	25	9	concentration	concentration	NOUN
admet-2859	25	10	of	of	ADP
admet-2859	25	11	a	a	DET
admet-2859	25	12	dissolved	dissolve	VERB
admet-2859	25	13	drug	drug	NOUN
admet-2859	25	14	in	in	ADP
admet-2859	25	15	the	the	DET
admet-2859	25	16	acceptor	acceptor	NOUN
admet-2859	25	17	compartment	compartment	NOUN
admet-2859	25	18	remains	remain	VERB
admet-2859	25	19	significantly	significantly	ADV
admet-2859	25	20	lower	low	ADJ
admet-2859	25	21	than	than	ADP
admet-2859	25	22	the	the	DET
admet-2859	25	23	saturation	saturation	NOUN
admet-2859	25	24	solubility	solubility	NOUN
admet-2859	25	25	,	,	PUNCT
admet-2859	25	26	hence	hence	ADV
admet-2859	25	27	preserving	preserve	VERB
admet-2859	25	28	a	a	DET
admet-2859	25	29	constant	constant	ADJ
admet-2859	25	30	driving	driving	NOUN
admet-2859	25	31	force	force	NOUN
admet-2859	25	32	for	for	ADP
admet-2859	25	33	drug	drug	NOUN
admet-2859	25	34	diffusion	diffusion	NOUN
admet-2859	25	35	and	and	CCONJ
admet-2859	25	36	ensuring	ensure	VERB
admet-2859	25	37	that	that	SCONJ
admet-2859	25	38	the	the	DET
admet-2859	25	39	absorption	absorption	NOUN
admet-2859	25	40	rate	rate	NOUN
admet-2859	25	41	is	be	AUX
admet-2859	25	42	unaffected	unaffected	ADJ
admet-2859	25	43	by	by	ADP
admet-2859	25	44	the	the	DET
admet-2859	25	45	concentration	concentration	NOUN
admet-2859	25	46	gradient	gradient	NOUN
admet-2859	25	47	[	[	X
admet-2859	25	48	7,8	7,8	NUM
admet-2859	25	49	]	]	PUNCT
admet-2859	25	50	.	.	PUNCT
admet-2859	26	1	this	this	DET
admet-2859	26	2	concept	concept	NOUN
admet-2859	26	3	originates	originate	NOUN
admet-2859	26	4	from	from	ADP
admet-2859	26	5	walter	walter	PROPN
admet-2859	26	6	nernst	nernst	PROPN
admet-2859	27	1	[	[	X
admet-2859	27	2	9	9	NUM
admet-2859	27	3	]	]	PUNCT
admet-2859	27	4	,	,	PUNCT
admet-2859	27	5	who	who	PRON
admet-2859	27	6	described	describe	VERB
admet-2859	27	7	the	the	DET
admet-2859	27	8	impact	impact	NOUN
admet-2859	27	9	of	of	ADP
admet-2859	27	10	concentration	concentration	NOUN
admet-2859	27	11	gradients	gradient	NOUN
admet-2859	27	12	on	on	ADP
admet-2859	27	13	the	the	DET
admet-2859	27	14	diffusion	diffusion	NOUN
admet-2859	27	15	rate	rate	NOUN
admet-2859	27	16	in	in	ADP
admet-2859	27	17	his	his	PRON
admet-2859	27	18	work	work	NOUN
admet-2859	27	19	on	on	ADP
admet-2859	27	20	diffusion	diffusion	NOUN
admet-2859	27	21	laws	law	NOUN
admet-2859	27	22	.	.	PUNCT
admet-2859	28	1	although	although	SCONJ
admet-2859	28	2	nernst	nernst	PROPN
admet-2859	28	3	did	do	AUX
admet-2859	28	4	not	not	PART
admet-2859	28	5	explicitly	explicitly	ADV
admet-2859	28	6	employ	employ	VERB
admet-2859	28	7	the	the	DET
admet-2859	28	8	phrase	phrase	NOUN
admet-2859	28	9	sink	sink	NOUN
admet-2859	28	10	condition	condition	NOUN
admet-2859	28	11	,	,	PUNCT
admet-2859	28	12	his	his	PRON
admet-2859	28	13	equations	equation	NOUN
admet-2859	28	14	established	establish	VERB
admet-2859	28	15	an	an	DET
admet-2859	28	16	initial	initial	ADJ
admet-2859	28	17	basis	basis	NOUN
admet-2859	28	18	for	for	ADP
admet-2859	28	19	comprehending	comprehend	VERB
admet-2859	28	20	how	how	SCONJ
admet-2859	28	21	maintaining	maintain	VERB
admet-2859	28	22	low	low	ADJ
admet-2859	28	23	concentrations	concentration	NOUN
admet-2859	28	24	in	in	ADP
admet-2859	28	25	the	the	DET
admet-2859	28	26	receiving	receive	VERB
admet-2859	28	27	phase	phase	NOUN
admet-2859	28	28	aids	aid	VERB
admet-2859	28	29	continuous	continuous	ADJ
admet-2859	28	30	diffusion	diffusion	NOUN
admet-2859	28	31	.	.	PUNCT
admet-2859	29	1	the	the	DET
admet-2859	29	2	term	term	NOUN
admet-2859	29	3	and	and	CCONJ
admet-2859	29	4	its	its	PRON
admet-2859	29	5	specific	specific	ADJ
admet-2859	29	6	application	application	NOUN
admet-2859	29	7	to	to	ADP
admet-2859	29	8	drug	drug	NOUN
admet-2859	29	9	dissolution	dissolution	NOUN
admet-2859	29	10	became	became	AUX
admet-2859	29	11	more	more	ADV
admet-2859	29	12	widely	widely	ADV
admet-2859	29	13	recognized	recognize	VERB
admet-2859	29	14	through	through	ADP
admet-2859	29	15	the	the	DET
admet-2859	29	16	work	work	NOUN
admet-2859	29	17	of	of	ADP
admet-2859	29	18	higuchi	higuchi	PROPN
admet-2859	29	19	in	in	ADP
admet-2859	29	20	the	the	DET
admet-2859	29	21	1960s	1960s	NUM
admet-2859	29	22	.	.	PUNCT
admet-2859	30	1	higuchi	higuchi	PROPN
admet-2859	30	2	highlighted	highlight	VERB
admet-2859	30	3	the	the	DET
admet-2859	30	4	importance	importance	NOUN
admet-2859	30	5	of	of	ADP
admet-2859	30	6	maintaining	maintain	VERB
admet-2859	30	7	sink	sink	NOUN
admet-2859	30	8	conditions	condition	NOUN
admet-2859	30	9	to	to	PART
admet-2859	30	10	ensure	ensure	VERB
admet-2859	30	11	accurate	accurate	ADJ
admet-2859	30	12	measurement	measurement	NOUN
admet-2859	30	13	of	of	ADP
admet-2859	30	14	drug	drug	NOUN
admet-2859	30	15	dissolution	dissolution	NOUN
admet-2859	30	16	rates	rate	NOUN
admet-2859	30	17	,	,	PUNCT
admet-2859	30	18	emphasizing	emphasize	VERB
admet-2859	30	19	that	that	SCONJ
admet-2859	30	20	without	without	ADP
admet-2859	30	21	sink	sink	NOUN
admet-2859	30	22	conditions	condition	NOUN
admet-2859	30	23	,	,	PUNCT
admet-2859	30	24	the	the	DET
admet-2859	30	25	release	release	NOUN
admet-2859	30	26	rate	rate	NOUN
admet-2859	30	27	of	of	ADP
admet-2859	30	28	drugs	drug	NOUN
admet-2859	30	29	could	could	AUX
admet-2859	30	30	be	be	AUX
admet-2859	30	31	significantly	significantly	ADV
admet-2859	30	32	underestimated	underestimate	VERB
admet-2859	30	33	.	.	PUNCT
admet-2859	31	1	his	his	PRON
admet-2859	31	2	research	research	NOUN
admet-2859	31	3	was	be	AUX
admet-2859	31	4	pivotal	pivotal	ADJ
admet-2859	31	5	in	in	ADP
admet-2859	31	6	adapting	adapt	VERB
admet-2859	31	7	the	the	DET
admet-2859	31	8	concept	concept	NOUN
admet-2859	31	9	for	for	ADP
admet-2859	31	10	use	use	NOUN
admet-2859	31	11	in	in	ADP
admet-2859	31	12	pharmaceutical	pharmaceutical	ADJ
admet-2859	31	13	sciences	science	NOUN
admet-2859	31	14	,	,	PUNCT
admet-2859	31	15	providing	provide	VERB
admet-2859	31	16	a	a	DET
admet-2859	31	17	clear	clear	ADJ
admet-2859	31	18	methodology	methodology	NOUN
admet-2859	31	19	for	for	ADP
admet-2859	31	20	studying	study	VERB
admet-2859	31	21	the	the	DET
admet-2859	31	22	release	release	NOUN
admet-2859	31	23	of	of	ADP
admet-2859	31	24	drugs	drug	NOUN
admet-2859	31	25	from	from	ADP
admet-2859	31	26	formulations	formulation	NOUN
admet-2859	31	27	[	[	PUNCT
admet-2859	31	28	10	10	NUM
admet-2859	31	29	-	-	SYM
admet-2859	31	30	12	12	NUM
admet-2859	31	31	]	]	PUNCT
admet-2859	31	32	.	.	PUNCT
admet-2859	32	1	alex	alex	PROPN
admet-2859	32	2	avdeef	avdeef	PROPN
admet-2859	32	3	expanded	expand	VERB
admet-2859	32	4	the	the	DET
admet-2859	32	5	comprehension	comprehension	NOUN
admet-2859	32	6	of	of	ADP
admet-2859	32	7	sink	sink	NOUN
admet-2859	32	8	conditions	condition	NOUN
admet-2859	32	9	within	within	ADP
admet-2859	32	10	permeability	permeability	NOUN
admet-2859	32	11	studies	study	NOUN
admet-2859	32	12	.	.	PUNCT
admet-2859	33	1	in	in	ADP
admet-2859	33	2	his	his	PRON
admet-2859	33	3	2003	2003	NUM
admet-2859	33	4	book	book	NOUN
admet-2859	33	5	,	,	PUNCT
admet-2859	33	6	avdeef	avdeef	VERB
admet-2859	33	7	[	[	X
admet-2859	33	8	13	13	NUM
admet-2859	33	9	]	]	PUNCT
admet-2859	33	10	revealed	reveal	VERB
admet-2859	33	11	the	the	DET
admet-2859	33	12	essential	essential	ADJ
admet-2859	33	13	function	function	NOUN
admet-2859	33	14	of	of	ADP
admet-2859	33	15	sink	sink	NOUN
admet-2859	33	16	conditions	condition	NOUN
admet-2859	33	17	in	in	ADV
admet-2859	33	18	in	in	ADP
admet-2859	33	19	vitro	vitro	X
admet-2859	33	20	permeability	permeability	NOUN
admet-2859	33	21	assays	assay	NOUN
admet-2859	33	22	,	,	PUNCT
admet-2859	33	23	such	such	ADJ
admet-2859	33	24	as	as	ADP
admet-2859	33	25	caco-2	caco-2	NUM
admet-2859	33	26	and	and	CCONJ
admet-2859	33	27	pampa	pampa	NOUN
admet-2859	33	28	models	model	NOUN
admet-2859	33	29	.	.	PUNCT
admet-2859	34	1	he	he	PRON
admet-2859	34	2	argued	argue	VERB
admet-2859	34	3	that	that	SCONJ
admet-2859	34	4	maintaining	maintain	VERB
admet-2859	34	5	sink	sink	NOUN
admet-2859	34	6	conditions	condition	NOUN
admet-2859	34	7	is	be	AUX
admet-2859	34	8	crucial	crucial	ADJ
admet-2859	34	9	for	for	ADP
admet-2859	34	10	accurately	accurately	ADV
admet-2859	34	11	representing	represent	VERB
admet-2859	34	12	physiological	physiological	ADJ
admet-2859	34	13	conditions	condition	NOUN
admet-2859	34	14	,	,	PUNCT
admet-2859	34	15	as	as	SCONJ
admet-2859	34	16	it	it	PRON
admet-2859	34	17	prevents	prevent	VERB
admet-2859	34	18	the	the	DET
admet-2859	34	19	dissolution	dissolution	NOUN
admet-2859	34	20	rate	rate	NOUN
admet-2859	34	21	from	from	ADP
admet-2859	34	22	being	be	AUX
admet-2859	34	23	limited	limit	VERB
admet-2859	34	24	by	by	ADP
admet-2859	34	25	the	the	DET
admet-2859	34	26	accumulation	accumulation	NOUN
admet-2859	34	27	of	of	ADP
admet-2859	34	28	drugs	drug	NOUN
admet-2859	34	29	in	in	ADP
admet-2859	34	30	the	the	DET
admet-2859	34	31	receiver	receiver	ADJ
admet-2859	34	32	solution	solution	NOUN
admet-2859	34	33	.	.	PUNCT
admet-2859	35	1	avdeef	avdeef	PROPN
admet-2859	35	2	also	also	ADV
admet-2859	35	3	noticed	notice	VERB
admet-2859	35	4	that	that	SCONJ
admet-2859	35	5	in	in	ADP
admet-2859	35	6	the	the	DET
admet-2859	35	7	absence	absence	NOUN
admet-2859	35	8	of	of	ADP
admet-2859	35	9	sink	sink	NOUN
admet-2859	35	10	conditions	condition	NOUN
admet-2859	35	11	,	,	PUNCT
admet-2859	35	12	the	the	DET
admet-2859	35	13	observed	observed	ADJ
admet-2859	35	14	permeability	permeability	NOUN
admet-2859	35	15	may	may	AUX
admet-2859	35	16	underrepresent	underrepresent	VERB
admet-2859	35	17	a	a	DET
admet-2859	35	18	drug	drug	NOUN
admet-2859	35	19	's	's	PART
admet-2859	35	20	real	real	ADJ
admet-2859	35	21	absorption	absorption	NOUN
admet-2859	35	22	capacity	capacity	NOUN
admet-2859	35	23	,	,	PUNCT
admet-2859	35	24	particularly	particularly	ADV
admet-2859	35	25	for	for	ADP
admet-2859	35	26	poorly	poorly	ADV
admet-2859	35	27	soluble	soluble	ADJ
admet-2859	35	28	molecules	molecule	NOUN
admet-2859	35	29	.	.	PUNCT
admet-2859	36	1	solubilizing	solubilize	VERB
admet-2859	36	2	agents	agent	NOUN
admet-2859	36	3	like	like	ADP
admet-2859	36	4	sodium	sodium	NOUN
admet-2859	36	5	lauryl	lauryl	NOUN
admet-2859	36	6	sulphate	sulphate	NOUN
admet-2859	36	7	(	(	PUNCT
admet-2859	36	8	sls	sls	PROPN
admet-2859	36	9	)	)	PUNCT
admet-2859	36	10	and	and	CCONJ
admet-2859	36	11	complexing	complexe	VERB
admet-2859	36	12	agents	agent	NOUN
admet-2859	36	13	like	like	ADP
admet-2859	36	14	hpβ	hpβ	NOUN
admet-2859	36	15	-	-	PUNCT
admet-2859	36	16	cd	cd	NOUN
admet-2859	36	17	are	be	AUX
admet-2859	36	18	often	often	ADV
admet-2859	36	19	used	use	VERB
admet-2859	36	20	in	in	ADP
admet-2859	36	21	acceptor	acceptor	NOUN
admet-2859	36	22	media	medium	NOUN
admet-2859	36	23	to	to	PART
admet-2859	36	24	create	create	VERB
admet-2859	36	25	sink	sink	NOUN
admet-2859	36	26	conditions	condition	NOUN
admet-2859	36	27	[	[	X
admet-2859	36	28	3,13	3,13	NUM
admet-2859	36	29	-	-	SYM
admet-2859	36	30	18	18	NUM
admet-2859	36	31	]	]	PUNCT
admet-2859	36	32	.	.	PUNCT
admet-2859	37	1	while	while	SCONJ
admet-2859	37	2	micelle	micelle	NOUN
admet-2859	37	3	-	-	PUNCT
admet-2859	37	4	forming	form	VERB
admet-2859	37	5	agents	agent	NOUN
admet-2859	37	6	generally	generally	ADV
admet-2859	37	7	enhance	enhance	VERB
admet-2859	37	8	the	the	DET
admet-2859	37	9	solubility	solubility	NOUN
admet-2859	37	10	of	of	ADP
admet-2859	37	11	poorly	poorly	ADV
admet-2859	37	12	water	water	NOUN
admet-2859	37	13	-	-	PUNCT
admet-2859	37	14	soluble	soluble	ADJ
admet-2859	37	15	drugs	drug	NOUN
admet-2859	37	16	,	,	PUNCT
admet-2859	37	17	for	for	ADP
admet-2859	37	18	complexing	complexe	VERB
admet-2859	37	19	agents	agent	NOUN
admet-2859	37	20	to	to	PART
admet-2859	37	21	be	be	AUX
admet-2859	37	22	effective	effective	ADJ
admet-2859	37	23	solubilizers	solubilizer	NOUN
admet-2859	37	24	,	,	PUNCT
admet-2859	37	25	they	they	PRON
admet-2859	37	26	need	need	VERB
admet-2859	37	27	to	to	PART
admet-2859	37	28	have	have	VERB
admet-2859	37	29	molecular	molecular	ADJ
admet-2859	37	30	interaction	interaction	NOUN
admet-2859	37	31	,	,	PUNCT
admet-2859	37	32	which	which	PRON
admet-2859	37	33	depends	depend	VERB
admet-2859	37	34	on	on	ADP
admet-2859	37	35	the	the	DET
admet-2859	37	36	size	size	NOUN
admet-2859	37	37	of	of	ADP
admet-2859	37	38	the	the	DET
admet-2859	37	39	molecule	molecule	NOUN
admet-2859	37	40	;	;	PUNCT
admet-2859	37	41	therefore	therefore	ADV
admet-2859	37	42	,	,	PUNCT
admet-2859	37	43	their	their	PRON
admet-2859	37	44	effectiveness	effectiveness	NOUN
admet-2859	37	45	is	be	AUX
admet-2859	37	46	highly	highly	ADV
admet-2859	37	47	selective	selective	ADJ
admet-2859	37	48	.	.	PUNCT
admet-2859	38	1	carvedilol	carvedilol	NOUN
admet-2859	38	2	(	(	PUNCT
admet-2859	38	3	car	car	NOUN
admet-2859	38	4	)	)	PUNCT
admet-2859	38	5	,	,	PUNCT
admet-2859	38	6	a	a	DET
admet-2859	38	7	non	non	ADJ
admet-2859	38	8	-	-	ADJ
admet-2859	38	9	selective	selective	ADJ
admet-2859	38	10	β	β	NOUN
admet-2859	38	11	-	-	NOUN
admet-2859	38	12	receptor	receptor	NOUN
admet-2859	38	13	blocker	blocker	NOUN
admet-2859	38	14	,	,	PUNCT
admet-2859	38	15	was	be	AUX
admet-2859	38	16	chosen	choose	VERB
admet-2859	38	17	as	as	ADP
admet-2859	38	18	the	the	DET
admet-2859	38	19	model	model	NOUN
admet-2859	38	20	active	active	ADJ
admet-2859	38	21	pharmaceutical	pharmaceutical	ADJ
admet-2859	38	22	ingredient	ingredient	NOUN
admet-2859	38	23	(	(	PUNCT
admet-2859	38	24	api	api	NOUN
admet-2859	38	25	)	)	PUNCT
admet-2859	38	26	,	,	PUNCT
admet-2859	38	27	while	while	SCONJ
admet-2859	38	28	as	as	SCONJ
admet-2859	38	29	the	the	DET
admet-2859	38	30	model	model	NOUN
admet-2859	38	31	solubilizing	solubilize	VERB
admet-2859	38	32	additive	additive	NOUN
admet-2859	38	33	with	with	ADP
admet-2859	38	34	known	know	VERB
admet-2859	38	35	size	size	NOUN
admet-2859	38	36	and	and	CCONJ
admet-2859	38	37	attributes	attribute	NOUN
admet-2859	38	38	,	,	PUNCT
admet-2859	38	39	hp	hp	PROPN
admet-2859	38	40	-	-	PUNCT
admet-2859	38	41	β	β	NOUN
admet-2859	38	42	-	-	NOUN
admet-2859	38	43	cd	cd	PROPN
admet-2859	38	44	was	be	AUX
admet-2859	38	45	chosen	choose	VERB
admet-2859	38	46	,	,	PUNCT
admet-2859	38	47	which	which	PRON
admet-2859	38	48	shows	show	VERB
admet-2859	38	49	the	the	DET
admet-2859	38	50	highest	high	ADJ
admet-2859	38	51	complexation	complexation	NOUN
admet-2859	38	52	efficiency	efficiency	NOUN
admet-2859	38	53	(	(	PUNCT
admet-2859	38	54	ce	ce	PROPN
admet-2859	38	55	)	)	PUNCT
admet-2859	38	56	with	with	ADP
admet-2859	38	57	car	car	NOUN
admet-2859	38	58	among	among	ADP
admet-2859	38	59	the	the	DET
admet-2859	38	60	cds	cd	NOUN
admet-2859	39	1	[	[	X
admet-2859	39	2	19	19	NUM
admet-2859	39	3	-	-	SYM
admet-2859	39	4	21	21	NUM
admet-2859	39	5	]	]	PUNCT
admet-2859	39	6	.	.	PUNCT
admet-2859	40	1	lipophilic	lipophilic	ADJ
admet-2859	40	2	membranes	membrane	NOUN
admet-2859	40	3	,	,	PUNCT
admet-2859	40	4	typically	typically	ADV
admet-2859	40	5	phospholipid	phospholipid	NOUN
admet-2859	40	6	-	-	PUNCT
admet-2859	40	7	coated	coat	VERB
admet-2859	40	8	filters	filter	NOUN
admet-2859	40	9	[	[	PUNCT
admet-2859	40	10	22	22	NUM
admet-2859	40	11	-	-	SYM
admet-2859	40	12	30	30	NUM
admet-2859	40	13	]	]	PUNCT
admet-2859	40	14	,	,	PUNCT
admet-2859	40	15	are	be	AUX
admet-2859	40	16	widely	widely	ADV
admet-2859	40	17	used	use	VERB
admet-2859	40	18	to	to	PART
admet-2859	40	19	mimic	mimic	VERB
admet-2859	40	20	passive	passive	ADJ
admet-2859	40	21	transcellular	transcellular	NOUN
admet-2859	40	22	diffusion	diffusion	NOUN
admet-2859	40	23	across	across	ADP
admet-2859	40	24	the	the	DET
admet-2859	40	25	epithelial	epithelial	ADJ
admet-2859	40	26	layer	layer	NOUN
admet-2859	40	27	of	of	ADP
admet-2859	40	28	the	the	DET
admet-2859	40	29	gastrointestinal	gastrointestinal	ADJ
admet-2859	40	30	(	(	PUNCT
admet-2859	40	31	gi	gi	INTJ
admet-2859	40	32	)	)	PUNCT
admet-2859	40	33	tract	tract	NOUN
admet-2859	40	34	.	.	PUNCT
admet-2859	41	1	these	these	DET
admet-2859	41	2	membranes	membrane	NOUN
admet-2859	41	3	simulate	simulate	VERB
admet-2859	41	4	the	the	DET
admet-2859	41	5	lipid	lipid	ADJ
admet-2859	41	6	bilayer	bilayer	NOUN
admet-2859	41	7	of	of	ADP
admet-2859	41	8	cell	cell	NOUN
admet-2859	41	9	membranes	membrane	NOUN
admet-2859	41	10	,	,	PUNCT
admet-2859	41	11	requiring	require	VERB
admet-2859	41	12	drugs	drug	NOUN
admet-2859	41	13	to	to	PART
admet-2859	41	14	partition	partition	VERB
admet-2859	41	15	into	into	ADP
admet-2859	41	16	a	a	DET
admet-2859	41	17	lipophilic	lipophilic	ADJ
admet-2859	41	18	phase	phase	NOUN
admet-2859	41	19	before	before	ADP
admet-2859	41	20	diffusing	diffuse	VERB
admet-2859	41	21	into	into	ADP
admet-2859	41	22	the	the	DET
admet-2859	41	23	acceptor	acceptor	NOUN
admet-2859	41	24	side	side	NOUN
admet-2859	41	25	.	.	PUNCT
admet-2859	42	1	conversely	conversely	ADV
admet-2859	42	2	,	,	PUNCT
admet-2859	42	3	size	size	NOUN
admet-2859	42	4	-	-	PUNCT
admet-2859	42	5	exclusion	exclusion	NOUN
admet-2859	42	6	membranes	membrane	NOUN
admet-2859	42	7	[	[	X
admet-2859	42	8	31	31	NUM
admet-2859	42	9	-	-	SYM
admet-2859	42	10	41	41	NUM
admet-2859	42	11	]	]	PUNCT
admet-2859	42	12	function	function	NOUN
admet-2859	42	13	based	base	VERB
admet-2859	42	14	on	on	ADP
admet-2859	42	15	molecular	molecular	ADJ
admet-2859	42	16	size	size	NOUN
admet-2859	42	17	,	,	PUNCT
admet-2859	42	18	allowing	allow	VERB
admet-2859	42	19	admet	admet	PROPN
admet-2859	42	20	&	&	CCONJ
admet-2859	42	21	dmpk	dmpk	PROPN
admet-2859	42	22	13(5	13(5	NOUN
admet-2859	42	23	)	)	PUNCT
admet-2859	42	24	(	(	PUNCT
admet-2859	42	25	2025	2025	NUM
admet-2859	42	26	)	)	PUNCT
admet-2859	42	27	2859	2859	NUM
admet-2859	42	28	comparison	comparison	NOUN
admet-2859	42	29	of	of	ADP
admet-2859	42	30	lipophilic	lipophilic	ADJ
admet-2859	42	31	and	and	CCONJ
admet-2859	42	32	size	size	NOUN
admet-2859	42	33	-	-	PUNCT
admet-2859	42	34	exclusion	exclusion	NOUN
admet-2859	42	35	membranes	membrane	NOUN
admet-2859	42	36	doi	doi	NOUN
admet-2859	42	37	:	:	PUNCT
admet-2859	42	38	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	X
admet-2859	42	39	3	3	NUM
admet-2859	42	40	only	only	ADV
admet-2859	42	41	small	small	ADJ
admet-2859	42	42	molecules	molecule	NOUN
admet-2859	42	43	to	to	PART
admet-2859	42	44	diffuse	diffuse	VERB
admet-2859	42	45	through	through	ADP
admet-2859	42	46	their	their	PRON
admet-2859	42	47	water	water	NOUN
admet-2859	42	48	-	-	PUNCT
admet-2859	42	49	filled	fill	VERB
admet-2859	42	50	pores	pore	NOUN
admet-2859	42	51	.	.	PUNCT
admet-2859	43	1	since	since	SCONJ
admet-2859	43	2	these	these	DET
admet-2859	43	3	membranes	membrane	NOUN
admet-2859	43	4	can	can	AUX
admet-2859	43	5	not	not	PART
admet-2859	43	6	differentiate	differentiate	VERB
admet-2859	43	7	between	between	ADP
admet-2859	43	8	ionized	ionized	ADJ
admet-2859	43	9	and	and	CCONJ
admet-2859	43	10	neutral	neutral	ADJ
admet-2859	43	11	molecules	molecule	NOUN
admet-2859	43	12	,	,	PUNCT
admet-2859	43	13	due	due	ADP
admet-2859	43	14	to	to	ADP
admet-2859	43	15	the	the	DET
admet-2859	43	16	absence	absence	NOUN
admet-2859	43	17	of	of	ADP
admet-2859	43	18	a	a	DET
admet-2859	43	19	lipophilic	lipophilic	ADJ
admet-2859	43	20	domain	domain	NOUN
admet-2859	43	21	,	,	PUNCT
admet-2859	43	22	the	the	DET
admet-2859	43	23	permeability	permeability	NOUN
admet-2859	43	24	shows	show	VERB
admet-2859	43	25	no	no	DET
admet-2859	43	26	ph	ph	ADJ
admet-2859	43	27	dependence	dependence	NOUN
admet-2859	43	28	[	[	X
admet-2859	43	29	1	1	NUM
admet-2859	43	30	]	]	PUNCT
admet-2859	43	31	.	.	PUNCT
admet-2859	44	1	this	this	DET
admet-2859	44	2	fundamental	fundamental	ADJ
admet-2859	44	3	difference	difference	NOUN
admet-2859	44	4	in	in	ADP
admet-2859	44	5	transport	transport	NOUN
admet-2859	44	6	mechanisms	mechanism	NOUN
admet-2859	44	7	raises	raise	VERB
admet-2859	44	8	the	the	DET
admet-2859	44	9	question	question	NOUN
admet-2859	44	10	of	of	ADP
admet-2859	44	11	whether	whether	SCONJ
admet-2859	44	12	size	size	NOUN
admet-2859	44	13	-	-	PUNCT
admet-2859	44	14	exclusion	exclusion	NOUN
admet-2859	44	15	membranes	membrane	NOUN
admet-2859	44	16	can	can	AUX
admet-2859	44	17	serve	serve	VERB
admet-2859	44	18	as	as	ADP
admet-2859	44	19	possible	possible	ADJ
admet-2859	44	20	alternatives	alternative	NOUN
admet-2859	44	21	to	to	ADP
admet-2859	44	22	lipophilic	lipophilic	ADJ
admet-2859	44	23	membranes	membrane	NOUN
admet-2859	44	24	for	for	ADP
admet-2859	44	25	permeability	permeability	NOUN
admet-2859	44	26	assessments	assessment	NOUN
admet-2859	44	27	,	,	PUNCT
admet-2859	44	28	particularly	particularly	ADV
admet-2859	44	29	in	in	ADP
admet-2859	44	30	cases	case	NOUN
admet-2859	44	31	involving	involve	VERB
admet-2859	44	32	solubilizing	solubilize	VERB
admet-2859	44	33	agents	agent	NOUN
admet-2859	44	34	.	.	PUNCT
admet-2859	45	1	transport	transport	NOUN
admet-2859	45	2	across	across	ADP
admet-2859	45	3	both	both	DET
admet-2859	45	4	membrane	membrane	NOUN
admet-2859	45	5	types	type	NOUN
admet-2859	45	6	can	can	AUX
admet-2859	45	7	be	be	AUX
admet-2859	45	8	membrane	membrane	NOUN
admet-2859	45	9	-	-	PUNCT
admet-2859	45	10	limited	limit	VERB
admet-2859	45	11	but	but	CCONJ
admet-2859	45	12	also	also	ADV
admet-2859	45	13	can	can	AUX
admet-2859	45	14	be	be	AUX
admet-2859	45	15	influenced	influence	VERB
admet-2859	45	16	by	by	ADP
admet-2859	45	17	the	the	DET
admet-2859	45	18	unstirred	unstirred	ADJ
admet-2859	45	19	water	water	NOUN
admet-2859	45	20	layer	layer	NOUN
admet-2859	45	21	(	(	PUNCT
admet-2859	45	22	uwl	uwl	NOUN
admet-2859	45	23	)	)	PUNCT
admet-2859	45	24	,	,	PUNCT
admet-2859	45	25	which	which	PRON
admet-2859	45	26	creates	create	VERB
admet-2859	45	27	an	an	DET
admet-2859	45	28	additional	additional	ADJ
admet-2859	45	29	diffusional	diffusional	ADJ
admet-2859	45	30	barrier	barrier	NOUN
admet-2859	45	31	at	at	ADP
admet-2859	45	32	the	the	DET
admet-2859	45	33	membrane	membrane	NOUN
admet-2859	45	34	interface	interface	NOUN
admet-2859	45	35	.	.	PUNCT
admet-2859	46	1	in	in	ADP
admet-2859	46	2	lipophilic	lipophilic	ADJ
admet-2859	46	3	membranes	membrane	NOUN
admet-2859	46	4	,	,	PUNCT
admet-2859	46	5	drug	drug	NOUN
admet-2859	46	6	molecules	molecule	NOUN
admet-2859	46	7	must	must	AUX
admet-2859	46	8	overcome	overcome	VERB
admet-2859	46	9	the	the	DET
admet-2859	46	10	uwl	uwl	NOUN
admet-2859	46	11	before	before	ADP
admet-2859	46	12	partitioning	partition	VERB
admet-2859	46	13	into	into	ADP
admet-2859	46	14	the	the	DET
admet-2859	46	15	lipophilic	lipophilic	ADJ
admet-2859	46	16	phase	phase	NOUN
admet-2859	46	17	,	,	PUNCT
admet-2859	46	18	while	while	SCONJ
admet-2859	46	19	in	in	ADP
admet-2859	46	20	size	size	NOUN
admet-2859	46	21	-	-	PUNCT
admet-2859	46	22	exclusion	exclusion	NOUN
admet-2859	46	23	membranes	membrane	NOUN
admet-2859	46	24	,	,	PUNCT
admet-2859	46	25	the	the	DET
admet-2859	46	26	transport	transport	NOUN
admet-2859	46	27	occurs	occur	VERB
admet-2859	46	28	entirely	entirely	ADV
admet-2859	46	29	in	in	ADP
admet-2859	46	30	an	an	DET
admet-2859	46	31	aqueous	aqueous	ADJ
admet-2859	46	32	environment	environment	NOUN
admet-2859	46	33	.	.	PUNCT
admet-2859	47	1	however	however	ADV
admet-2859	47	2	,	,	PUNCT
admet-2859	47	3	these	these	DET
admet-2859	47	4	two	two	NUM
admet-2859	47	5	aqueous	aqueous	ADJ
admet-2859	47	6	environments	environment	NOUN
admet-2859	47	7	may	may	AUX
admet-2859	47	8	differ	differ	VERB
admet-2859	47	9	significantly	significantly	ADV
admet-2859	47	10	because	because	SCONJ
admet-2859	47	11	of	of	ADP
admet-2859	47	12	the	the	DET
admet-2859	47	13	drug	drug	NOUN
admet-2859	47	14	's	's	PART
admet-2859	47	15	molecular	molecular	ADJ
admet-2859	47	16	hydration	hydration	NOUN
admet-2859	47	17	and	and	CCONJ
admet-2859	47	18	possible	possible	ADJ
admet-2859	47	19	interaction	interaction	NOUN
admet-2859	47	20	of	of	ADP
admet-2859	47	21	the	the	DET
admet-2859	47	22	drug	drug	NOUN
admet-2859	47	23	and	and	CCONJ
admet-2859	47	24	filter	filter	NOUN
admet-2859	47	25	material	material	NOUN
admet-2859	47	26	.	.	PUNCT
admet-2859	48	1	consequently	consequently	ADV
admet-2859	48	2	,	,	PUNCT
admet-2859	48	3	for	for	ADP
admet-2859	48	4	size	size	NOUN
admet-2859	48	5	-	-	PUNCT
admet-2859	48	6	exclusion	exclusion	NOUN
admet-2859	48	7	membranes	membrane	NOUN
admet-2859	48	8	,	,	PUNCT
admet-2859	48	9	both	both	CCONJ
admet-2859	48	10	the	the	DET
admet-2859	48	11	uwl	uwl	NOUN
admet-2859	48	12	and	and	CCONJ
admet-2859	48	13	the	the	DET
admet-2859	48	14	membrane	membrane	NOUN
admet-2859	48	15	permeation	permeation	NOUN
admet-2859	48	16	means	mean	VERB
admet-2859	48	17	aqueous	aqueous	ADJ
admet-2859	48	18	diffusion	diffusion	NOUN
admet-2859	48	19	and	and	CCONJ
admet-2859	48	20	no	no	DET
admet-2859	48	21	diffusion	diffusion	NOUN
admet-2859	48	22	through	through	SCONJ
admet-2859	48	23	a	a	DET
admet-2859	48	24	lipophilic	lipophilic	ADJ
admet-2859	48	25	phase	phase	NOUN
admet-2859	48	26	is	be	AUX
admet-2859	48	27	involved	involve	VERB
admet-2859	48	28	.	.	PUNCT
admet-2859	49	1	when	when	SCONJ
admet-2859	49	2	using	use	VERB
admet-2859	49	3	the	the	DET
admet-2859	49	4	same	same	ADJ
admet-2859	49	5	apparatus	apparatus	NOUN
admet-2859	49	6	(	(	PUNCT
admet-2859	49	7	side	side	NOUN
admet-2859	49	8	-	-	PUNCT
admet-2859	49	9	by	by	ADP
admet-2859	49	10	-	-	PUNCT
admet-2859	49	11	side	side	NOUN
admet-2859	49	12	diffusion	diffusion	NOUN
admet-2859	49	13	cell	cell	NOUN
admet-2859	49	14	)	)	PUNCT
admet-2859	49	15	,	,	PUNCT
admet-2859	49	16	it	it	PRON
admet-2859	49	17	can	can	AUX
admet-2859	49	18	be	be	AUX
admet-2859	49	19	assumed	assume	VERB
admet-2859	49	20	that	that	SCONJ
admet-2859	49	21	the	the	DET
admet-2859	49	22	uwl	uwl	NOUN
admet-2859	49	23	permeabilities	permeability	NOUN
admet-2859	49	24	and	and	CCONJ
admet-2859	49	25	the	the	DET
admet-2859	49	26	thickness	thickness	NOUN
admet-2859	49	27	of	of	ADP
admet-2859	49	28	the	the	DET
admet-2859	49	29	uwl	uwl	NOUN
admet-2859	49	30	are	be	AUX
admet-2859	49	31	the	the	DET
admet-2859	49	32	same	same	ADJ
admet-2859	49	33	for	for	ADP
admet-2859	49	34	lipophilic	lipophilic	ADJ
admet-2859	49	35	and	and	CCONJ
admet-2859	49	36	size	size	NOUN
admet-2859	49	37	-	-	PUNCT
admet-2859	49	38	exclusion	exclusion	NOUN
admet-2859	49	39	membranes	membrane	NOUN
admet-2859	49	40	when	when	SCONJ
admet-2859	49	41	the	the	DET
admet-2859	49	42	same	same	ADJ
admet-2859	49	43	donor	donor	NOUN
admet-2859	49	44	,	,	PUNCT
admet-2859	49	45	acceptor	acceptor	NOUN
admet-2859	49	46	media	medium	NOUN
admet-2859	49	47	and	and	CCONJ
admet-2859	49	48	stirring	stirring	NOUN
admet-2859	49	49	speed	speed	NOUN
admet-2859	49	50	are	be	AUX
admet-2859	49	51	applied	apply	VERB
admet-2859	49	52	[	[	PUNCT
admet-2859	49	53	1	1	NUM
admet-2859	49	54	]	]	PUNCT
admet-2859	49	55	.	.	PUNCT
admet-2859	50	1	in	in	ADP
admet-2859	50	2	the	the	DET
admet-2859	50	3	previous	previous	ADJ
admet-2859	50	4	publication	publication	NOUN
admet-2859	50	5	,	,	PUNCT
admet-2859	50	6	it	it	PRON
admet-2859	50	7	was	be	AUX
admet-2859	50	8	found	find	VERB
admet-2859	50	9	that	that	SCONJ
admet-2859	50	10	regardless	regardless	ADV
admet-2859	50	11	of	of	ADP
admet-2859	50	12	the	the	DET
admet-2859	50	13	limitation	limitation	NOUN
admet-2859	50	14	of	of	ADP
admet-2859	50	15	the	the	DET
admet-2859	50	16	transport	transport	NOUN
admet-2859	50	17	,	,	PUNCT
admet-2859	50	18	the	the	DET
admet-2859	50	19	supersaturation	supersaturation	NOUN
admet-2859	50	20	ratio	ratio	NOUN
admet-2859	50	21	(	(	PUNCT
admet-2859	50	22	ssr	ssr	PROPN
admet-2859	50	23	,	,	PUNCT
admet-2859	50	24	defined	define	VERB
admet-2859	50	25	as	as	ADP
admet-2859	50	26	the	the	DET
admet-2859	50	27	ratio	ratio	NOUN
admet-2859	50	28	of	of	ADP
admet-2859	50	29	the	the	DET
admet-2859	50	30	drug	drug	NOUN
admet-2859	50	31	concentration	concentration	NOUN
admet-2859	50	32	present	present	ADJ
admet-2859	50	33	in	in	ADP
admet-2859	50	34	solution	solution	NOUN
admet-2859	50	35	to	to	ADP
admet-2859	50	36	its	its	PRON
admet-2859	50	37	thermodynamic	thermodynamic	ADJ
admet-2859	50	38	solubility	solubility	NOUN
admet-2859	50	39	measured	measure	VERB
admet-2859	50	40	in	in	ADP
admet-2859	50	41	exactly	exactly	ADV
admet-2859	50	42	the	the	DET
admet-2859	50	43	same	same	ADJ
admet-2859	50	44	media	medium	NOUN
admet-2859	50	45	)	)	PUNCT
admet-2859	50	46	is	be	AUX
admet-2859	50	47	the	the	DET
admet-2859	50	48	driving	drive	VERB
admet-2859	50	49	force	force	NOUN
admet-2859	50	50	of	of	ADP
admet-2859	50	51	membrane	membrane	NOUN
admet-2859	50	52	transport	transport	NOUN
admet-2859	50	53	.	.	PUNCT
admet-2859	51	1	this	this	DET
admet-2859	51	2	statement	statement	NOUN
admet-2859	51	3	was	be	AUX
admet-2859	51	4	supported	support	VERB
admet-2859	51	5	with	with	ADP
admet-2859	51	6	a	a	DET
admet-2859	51	7	concentration	concentration	NOUN
admet-2859	51	8	-	-	PUNCT
admet-2859	51	9	based	base	VERB
admet-2859	51	10	mathematical	mathematical	ADJ
admet-2859	51	11	description	description	NOUN
admet-2859	51	12	and	and	CCONJ
admet-2859	51	13	experimental	experimental	ADJ
admet-2859	51	14	data	datum	NOUN
admet-2859	51	15	for	for	ADP
admet-2859	51	16	pure	pure	ADJ
admet-2859	51	17	api	api	NOUN
admet-2859	51	18	in	in	ADP
admet-2859	51	19	both	both	DET
admet-2859	51	20	compartments	compartment	NOUN
admet-2859	51	21	of	of	ADP
admet-2859	51	22	the	the	DET
admet-2859	51	23	side	side	NOUN
admet-2859	51	24	-	-	PUNCT
admet-2859	51	25	by	by	ADP
admet-2859	51	26	-	-	PUNCT
admet-2859	51	27	side	side	NOUN
admet-2859	51	28	diffusion	diffusion	NOUN
admet-2859	51	29	cell	cell	NOUN
admet-2859	51	30	and	and	CCONJ
admet-2859	51	31	for	for	ADP
admet-2859	51	32	complexing	complexe	VERB
admet-2859	51	33	agent	agent	NOUN
admet-2859	51	34	placed	place	VERB
admet-2859	51	35	in	in	ADP
admet-2859	51	36	the	the	DET
admet-2859	51	37	donor	donor	NOUN
admet-2859	51	38	compartment	compartment	NOUN
admet-2859	51	39	with	with	ADP
admet-2859	51	40	lipophilic	lipophilic	ADJ
admet-2859	51	41	membrane	membrane	NOUN
admet-2859	51	42	,	,	PUNCT
admet-2859	51	43	where	where	SCONJ
admet-2859	51	44	only	only	ADV
admet-2859	51	45	the	the	DET
admet-2859	51	46	drug	drug	NOUN
admet-2859	51	47	molecules	molecule	NOUN
admet-2859	51	48	could	could	AUX
admet-2859	51	49	go	go	VERB
admet-2859	51	50	through	through	ADP
admet-2859	51	51	the	the	DET
admet-2859	51	52	membrane	membrane	NOUN
admet-2859	51	53	,	,	PUNCT
admet-2859	51	54	and	and	CCONJ
admet-2859	51	55	also	also	ADV
admet-2859	51	56	with	with	ADP
admet-2859	51	57	1	1	NUM
admet-2859	51	58	kda	kda	NOUN
admet-2859	51	59	molecular	molecular	ADJ
admet-2859	51	60	weight	weight	NOUN
admet-2859	51	61	cut	cut	NOUN
admet-2859	51	62	-	-	PUNCT
admet-2859	51	63	off	off	NOUN
admet-2859	51	64	(	(	PUNCT
admet-2859	51	65	mwco	mwco	NOUN
admet-2859	51	66	)	)	PUNCT
admet-2859	51	67	size	size	NOUN
admet-2859	51	68	-	-	PUNCT
admet-2859	51	69	exclusion	exclusion	NOUN
admet-2859	51	70	membrane	membrane	NOUN
admet-2859	51	71	,	,	PUNCT
admet-2859	51	72	where	where	SCONJ
admet-2859	51	73	the	the	DET
admet-2859	51	74	permeation	permeation	NOUN
admet-2859	51	75	of	of	ADP
admet-2859	51	76	the	the	DET
admet-2859	51	77	complexing	complexe	VERB
admet-2859	51	78	agent	agent	NOUN
admet-2859	51	79	is	be	AUX
admet-2859	51	80	quite	quite	ADV
admet-2859	51	81	slow	slow	ADJ
admet-2859	51	82	,	,	PUNCT
admet-2859	51	83	so	so	CCONJ
admet-2859	51	84	it	it	PRON
admet-2859	51	85	does	do	AUX
admet-2859	51	86	not	not	PART
admet-2859	51	87	affect	affect	VERB
admet-2859	51	88	the	the	DET
admet-2859	51	89	transport	transport	NOUN
admet-2859	51	90	of	of	ADP
admet-2859	51	91	the	the	DET
admet-2859	51	92	api	api	NOUN
admet-2859	51	93	substantially	substantially	ADV
admet-2859	51	94	.	.	PUNCT
admet-2859	52	1	in	in	ADP
admet-2859	52	2	the	the	DET
admet-2859	52	3	case	case	NOUN
admet-2859	52	4	the	the	DET
admet-2859	52	5	complexing	complexe	VERB
admet-2859	52	6	agent	agent	NOUN
admet-2859	52	7	(	(	PUNCT
admet-2859	52	8	hp	hp	PROPN
admet-2859	52	9	-	-	PUNCT
admet-2859	52	10	β	β	NOUN
admet-2859	52	11	-	-	NOUN
admet-2859	52	12	cd	cd	NOUN
admet-2859	52	13	)	)	PUNCT
admet-2859	52	14	is	be	AUX
admet-2859	52	15	transported	transport	VERB
admet-2859	52	16	through	through	ADP
admet-2859	52	17	the	the	DET
admet-2859	52	18	membrane	membrane	NOUN
admet-2859	52	19	in	in	ADP
admet-2859	52	20	a	a	DET
admet-2859	52	21	significant	significant	ADJ
admet-2859	52	22	amount	amount	NOUN
admet-2859	52	23	(	(	PUNCT
admet-2859	52	24	using	use	VERB
admet-2859	52	25	a	a	DET
admet-2859	52	26	size	size	NOUN
admet-2859	52	27	-	-	PUNCT
admet-2859	52	28	exclusion	exclusion	NOUN
admet-2859	52	29	membrane	membrane	NOUN
admet-2859	52	30	with	with	ADP
admet-2859	52	31	6	6	NUM
admet-2859	52	32	kda	kda	NOUN
admet-2859	52	33	mwco	mwco	PROPN
admet-2859	52	34	)	)	PUNCT
admet-2859	52	35	,	,	PUNCT
admet-2859	52	36	which	which	PRON
admet-2859	52	37	causes	cause	VERB
admet-2859	52	38	a	a	DET
admet-2859	52	39	significant	significant	ADJ
admet-2859	52	40	deviation	deviation	NOUN
admet-2859	52	41	from	from	ADP
admet-2859	52	42	the	the	DET
admet-2859	52	43	general	general	ADJ
admet-2859	52	44	mathematical	mathematical	ADJ
admet-2859	52	45	model	model	NOUN
admet-2859	52	46	.	.	PUNCT
admet-2859	53	1	in	in	ADP
admet-2859	53	2	conclusion	conclusion	NOUN
admet-2859	53	3	,	,	PUNCT
admet-2859	53	4	hence	hence	ADV
admet-2859	53	5	the	the	DET
admet-2859	53	6	fundamental	fundamental	ADJ
admet-2859	53	7	difference	difference	NOUN
admet-2859	53	8	in	in	ADP
admet-2859	53	9	transport	transport	NOUN
admet-2859	53	10	mechanisms	mechanism	NOUN
admet-2859	53	11	between	between	ADP
admet-2859	53	12	lipophilic	lipophilic	NOUN
admet-2859	53	13	and	and	CCONJ
admet-2859	53	14	size	size	NOUN
admet-2859	53	15	-	-	PUNCT
admet-2859	53	16	exclusion	exclusion	NOUN
admet-2859	53	17	membranes	membrane	NOUN
admet-2859	53	18	,	,	PUNCT
admet-2859	53	19	a	a	DET
admet-2859	53	20	1	1	NUM
admet-2859	53	21	kda	kda	NOUN
admet-2859	53	22	mwco	mwco	NOUN
admet-2859	53	23	membrane	membrane	NOUN
admet-2859	53	24	could	could	AUX
admet-2859	53	25	serve	serve	VERB
admet-2859	53	26	as	as	ADP
admet-2859	53	27	a	a	DET
admet-2859	53	28	possible	possible	ADJ
admet-2859	53	29	alternative	alternative	NOUN
admet-2859	53	30	to	to	ADP
admet-2859	53	31	lipophilic	lipophilic	ADJ
admet-2859	53	32	membranes	membrane	NOUN
admet-2859	53	33	for	for	ADP
admet-2859	53	34	permeability	permeability	NOUN
admet-2859	53	35	assessments	assessment	NOUN
admet-2859	53	36	in	in	ADP
admet-2859	53	37	cases	case	NOUN
admet-2859	53	38	involving	involve	VERB
admet-2859	53	39	hp	hp	NOUN
admet-2859	53	40	-	-	PUNCT
admet-2859	53	41	β	β	NOUN
admet-2859	53	42	-	-	NOUN
admet-2859	53	43	cd	cd	NOUN
admet-2859	53	44	in	in	ADP
admet-2859	53	45	the	the	DET
admet-2859	53	46	donor	donor	NOUN
admet-2859	53	47	compartment	compartment	NOUN
admet-2859	53	48	[	[	X
admet-2859	53	49	1	1	NUM
admet-2859	53	50	]	]	PUNCT
admet-2859	53	51	.	.	PUNCT
admet-2859	54	1	while	while	SCONJ
admet-2859	54	2	the	the	DET
admet-2859	54	3	effect	effect	NOUN
admet-2859	54	4	of	of	ADP
admet-2859	54	5	hp	hp	NOUN
admet-2859	54	6	-	-	PUNCT
admet-2859	54	7	β	β	NOUN
admet-2859	54	8	-	-	NOUN
admet-2859	54	9	cd	cd	NOUN
admet-2859	54	10	in	in	ADP
admet-2859	54	11	the	the	DET
admet-2859	54	12	donor	donor	NOUN
admet-2859	54	13	compartment	compartment	NOUN
admet-2859	54	14	was	be	AUX
admet-2859	54	15	previously	previously	ADV
admet-2859	54	16	published	publish	VERB
admet-2859	54	17	,	,	PUNCT
admet-2859	54	18	this	this	DET
admet-2859	54	19	study	study	NOUN
admet-2859	54	20	aims	aim	VERB
admet-2859	54	21	to	to	PART
admet-2859	54	22	investigate	investigate	VERB
admet-2859	54	23	the	the	DET
admet-2859	54	24	differences	difference	NOUN
admet-2859	54	25	in	in	ADP
admet-2859	54	26	supersaturation	supersaturation	NOUN
admet-2859	54	27	ratio	ratio	NOUN
admet-2859	54	28	and	and	CCONJ
admet-2859	54	29	permeability	permeability	NOUN
admet-2859	54	30	of	of	ADP
admet-2859	54	31	the	the	DET
admet-2859	54	32	model	model	NOUN
admet-2859	54	33	api	api	NOUN
admet-2859	54	34	,	,	PUNCT
admet-2859	54	35	car	car	NOUN
admet-2859	54	36	,	,	PUNCT
admet-2859	54	37	between	between	ADP
admet-2859	54	38	lipophilic	lipophilic	ADJ
admet-2859	54	39	(	(	PUNCT
admet-2859	54	40	n	n	CCONJ
admet-2859	54	41	-	-	PUNCT
admet-2859	54	42	dodecane	dodecane	NOUN
admet-2859	54	43	)	)	PUNCT
admet-2859	54	44	and	and	CCONJ
admet-2859	54	45	size	size	NOUN
admet-2859	54	46	-	-	PUNCT
admet-2859	54	47	exclusion	exclusion	NOUN
admet-2859	54	48	membranes	membrane	NOUN
admet-2859	54	49	,	,	PUNCT
admet-2859	54	50	with	with	ADP
admet-2859	54	51	hp	hp	PROPN
admet-2859	54	52	-	-	PUNCT
admet-2859	54	53	β	β	NOUN
admet-2859	54	54	-	-	NOUN
admet-2859	54	55	cd	cd	NOUN
admet-2859	54	56	present	present	NOUN
admet-2859	54	57	in	in	ADP
admet-2859	54	58	either	either	CCONJ
admet-2859	54	59	the	the	DET
admet-2859	54	60	acceptor	acceptor	NOUN
admet-2859	54	61	compartment	compartment	NOUN
admet-2859	54	62	or	or	CCONJ
admet-2859	54	63	both	both	DET
admet-2859	54	64	sides	side	NOUN
admet-2859	54	65	of	of	ADP
admet-2859	54	66	the	the	DET
admet-2859	54	67	membrane	membrane	NOUN
admet-2859	54	68	,	,	PUNCT
admet-2859	54	69	using	use	VERB
admet-2859	54	70	in	in	ADP
admet-2859	54	71	vitro	vitro	X
admet-2859	54	72	side	side	NOUN
admet-2859	54	73	-	-	PUNCT
admet-2859	54	74	by	by	ADP
admet-2859	54	75	-	-	PUNCT
admet-2859	54	76	side	side	NOUN
admet-2859	54	77	diffusion	diffusion	NOUN
admet-2859	54	78	cell	cell	NOUN
admet-2859	54	79	assays	assay	NOUN
admet-2859	54	80	.	.	PUNCT
admet-2859	55	1	the	the	DET
admet-2859	55	2	additional	additional	ADJ
admet-2859	55	3	objective	objective	NOUN
admet-2859	55	4	of	of	ADP
admet-2859	55	5	this	this	DET
admet-2859	55	6	research	research	NOUN
admet-2859	55	7	is	be	AUX
admet-2859	55	8	to	to	PART
admet-2859	55	9	assess	assess	VERB
admet-2859	55	10	the	the	DET
admet-2859	55	11	applicability	applicability	NOUN
admet-2859	55	12	of	of	ADP
admet-2859	55	13	a	a	DET
admet-2859	55	14	previously	previously	ADV
admet-2859	55	15	described	describe	VERB
admet-2859	55	16	general	general	ADJ
admet-2859	55	17	mathematical	mathematical	ADJ
admet-2859	55	18	equation	equation	NOUN
admet-2859	55	19	and	and	CCONJ
admet-2859	55	20	determine	determine	VERB
admet-2859	55	21	the	the	DET
admet-2859	55	22	driving	drive	VERB
admet-2859	55	23	force	force	NOUN
admet-2859	55	24	of	of	ADP
admet-2859	55	25	membrane	membrane	NOUN
admet-2859	55	26	transport	transport	NOUN
admet-2859	55	27	under	under	ADP
admet-2859	55	28	sink	sink	NOUN
admet-2859	55	29	conditions	condition	NOUN
admet-2859	55	30	.	.	PUNCT
admet-2859	56	1	experimental	experimental	ADJ
admet-2859	56	2	materials	material	NOUN
admet-2859	56	3	carvedilol	carvedilol	NOUN
admet-2859	56	4	(	(	PUNCT
admet-2859	56	5	car	car	NOUN
admet-2859	56	6	)	)	PUNCT
admet-2859	57	1	[	[	X
admet-2859	57	2	43	43	NUM
admet-2859	57	3	]	]	X
admet-2859	57	4	,	,	PUNCT
admet-2859	57	5	a	a	DET
admet-2859	57	6	poorly	poorly	ADV
admet-2859	57	7	water	water	NOUN
admet-2859	57	8	-	-	PUNCT
admet-2859	57	9	soluble	soluble	ADJ
admet-2859	57	10	but	but	CCONJ
admet-2859	57	11	well	well	ADV
admet-2859	57	12	-	-	PUNCT
admet-2859	57	13	permeable	permeable	ADJ
admet-2859	57	14	(	(	PUNCT
admet-2859	57	15	bcs	bcs	NOUN
admet-2859	57	16	class	class	PROPN
admet-2859	57	17	ii	ii	PROPN
admet-2859	57	18	)	)	PUNCT
admet-2859	57	19	,	,	PUNCT
admet-2859	57	20	monovalent	monovalent	VERB
admet-2859	57	21	weak	weak	ADJ
admet-2859	57	22	base	base	NOUN
admet-2859	57	23	with	with	ADP
admet-2859	57	24	a	a	DET
admet-2859	57	25	pka	pka	NOUN
admet-2859	57	26	of	of	ADP
admet-2859	57	27	7.97	7.97	NUM
admet-2859	57	28	(	(	PUNCT
admet-2859	57	29	25	25	NUM
admet-2859	57	30	°	°	NOUN
admet-2859	57	31	c	c	NOUN
admet-2859	57	32	,	,	PUNCT
admet-2859	57	33	0.15	0.15	NUM
admet-2859	57	34	m	m	NOUN
admet-2859	57	35	ionic	ionic	ADJ
admet-2859	57	36	strength	strength	NOUN
admet-2859	57	37	)	)	PUNCT
admet-2859	58	1	[	[	X
admet-2859	58	2	42	42	NUM
admet-2859	58	3	]	]	PUNCT
admet-2859	58	4	,	,	PUNCT
admet-2859	58	5	(	(	PUNCT
admet-2859	58	6	406.482	406.482	NUM
admet-2859	58	7	g	g	NOUN
admet-2859	58	8	mol-1	mol-1	NOUN
admet-2859	58	9	,	,	PUNCT
admet-2859	58	10	structure	structure	NOUN
admet-2859	58	11	shown	show	VERB
admet-2859	58	12	in	in	ADP
admet-2859	58	13	figure	figure	NOUN
admet-2859	58	14	1	1	NUM
admet-2859	58	15	.	.	PUNCT
admet-2859	58	16	)	)	PUNCT
admet-2859	58	17	,	,	PUNCT
admet-2859	58	18	was	be	AUX
admet-2859	58	19	obtained	obtain	VERB
admet-2859	58	20	from	from	ADP
admet-2859	58	21	sigma	sigma	PROPN
admet-2859	58	22	-	-	PUNCT
admet-2859	58	23	aldrich	aldrich	PROPN
admet-2859	58	24	co.	co.	PROPN
admet-2859	58	25	llc	llc	PROPN
admet-2859	58	26	.	.	PUNCT
admet-2859	59	1	(	(	PUNCT
admet-2859	59	2	st	st	PROPN
admet-2859	59	3	.	.	PROPN
admet-2859	59	4	louis	louis	PROPN
admet-2859	59	5	,	,	PUNCT
admet-2859	59	6	mo	mo	PROPN
admet-2859	59	7	,	,	PUNCT
admet-2859	59	8	usa	usa	PROPN
admet-2859	59	9	)	)	PUNCT
admet-2859	59	10	.	.	PUNCT
admet-2859	60	1	hp	hp	PROPN
admet-2859	60	2	-	-	PUNCT
admet-2859	60	3	β	β	NOUN
admet-2859	60	4	-	-	NOUN
admet-2859	60	5	cd	cd	NOUN
admet-2859	60	6	,	,	PUNCT
admet-2859	60	7	known	know	VERB
admet-2859	60	8	as	as	ADP
admet-2859	60	9	a	a	DET
admet-2859	60	10	solubilizing	solubilize	VERB
admet-2859	60	11	agent	agent	NOUN
admet-2859	60	12	,	,	PUNCT
admet-2859	60	13	is	be	AUX
admet-2859	60	14	a	a	DET
admet-2859	60	15	doughnut	doughnut	NOUN
admet-2859	60	16	-	-	PUNCT
admet-2859	60	17	shaped	shape	VERB
admet-2859	60	18	molecule	molecule	NOUN
admet-2859	60	19	composed	compose	VERB
admet-2859	60	20	of	of	ADP
admet-2859	60	21	seven	seven	NUM
admet-2859	60	22	alpha	alpha	NOUN
admet-2859	60	23	-	-	PUNCT
admet-2859	60	24	d	d	NOUN
admet-2859	60	25	-	-	PUNCT
admet-2859	60	26	glucopyranose	glucopyranose	NOUN
admet-2859	60	27	units[44	units[44	X
admet-2859	60	28	]	]	PUNCT
admet-2859	60	29	,	,	PUNCT
admet-2859	60	30	including	include	VERB
admet-2859	60	31	an	an	DET
admet-2859	60	32	internal	internal	ADJ
admet-2859	60	33	cavity	cavity	NOUN
admet-2859	60	34	(	(	PUNCT
admet-2859	60	35	ds	ds	ADJ
admet-2859	60	36	:	:	PUNCT
admet-2859	60	37	4.34	4.34	NUM
admet-2859	60	38	,	,	PUNCT
admet-2859	60	39	structure	structure	NOUN
admet-2859	60	40	shown	show	VERB
admet-2859	60	41	in	in	ADP
admet-2859	60	42	figure	figure	NOUN
admet-2859	60	43	1	1	NUM
admet-2859	60	44	)	)	PUNCT
admet-2859	60	45	,	,	PUNCT
admet-2859	60	46	was	be	AUX
admet-2859	60	47	obtained	obtain	VERB
admet-2859	60	48	from	from	ADP
admet-2859	60	49	roquette	roquette	NOUN
admet-2859	60	50	fréres	frére	NOUN
admet-2859	60	51	(	(	PUNCT
admet-2859	60	52	lestrem	lestrem	PROPN
admet-2859	60	53	,	,	PUNCT
admet-2859	60	54	france	france	PROPN
admet-2859	60	55	)	)	PUNCT
admet-2859	60	56	.	.	PUNCT
admet-2859	61	1	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	PROPN
admet-2859	62	1	p.	p.	NOUN
admet-2859	62	2	tőzsér	tőzsér	PROPN
admet-2859	62	3	et	et	PROPN
admet-2859	62	4	al	al	PROPN
admet-2859	62	5	.	.	PROPN
admet-2859	62	6	admet	admet	PROPN
admet-2859	62	7	&	&	CCONJ
admet-2859	62	8	dmpk	dmpk	PROPN
admet-2859	62	9	13(5	13(5	NUM
admet-2859	62	10	)	)	PUNCT
admet-2859	62	11	(	(	PUNCT
admet-2859	62	12	2025	2025	NUM
admet-2859	62	13	)	)	PUNCT
admet-2859	62	14	2859	2859	NUM
admet-2859	62	15	4	4	NUM
admet-2859	62	16	figure	figure	NOUN
admet-2859	62	17	1	1	NUM
admet-2859	62	18	.	.	PUNCT
admet-2859	63	1	the	the	DET
admet-2859	63	2	structural	structural	ADJ
admet-2859	63	3	formula	formula	NOUN
admet-2859	63	4	of	of	ADP
admet-2859	63	5	car	car	NOUN
admet-2859	63	6	and	and	CCONJ
admet-2859	63	7	hp	hp	PROPN
admet-2859	63	8	-	-	PUNCT
admet-2859	63	9	β	β	NOUN
admet-2859	63	10	-	-	ADJ
admet-2859	63	11	cd	cd	ADJ
admet-2859	63	12	prismaht	prismaht	NOUN
admet-2859	63	13	buffer	buffer	NOUN
admet-2859	63	14	and	and	CCONJ
admet-2859	63	15	polyvinylidene	polyvinylidene	NOUN
admet-2859	63	16	fluoride	fluoride	NOUN
admet-2859	63	17	(	(	PUNCT
admet-2859	63	18	pvdf	pvdf	PROPN
admet-2859	63	19	)	)	PUNCT
admet-2859	63	20	sheet	sheet	NOUN
admet-2859	63	21	with	with	ADP
admet-2859	63	22	0.45	0.45	NUM
admet-2859	63	23	µm	µm	ADP
admet-2859	63	24	pore	pore	ADJ
admet-2859	63	25	size	size	NOUN
admet-2859	63	26	were	be	AUX
admet-2859	63	27	purchased	purchase	VERB
admet-2859	63	28	from	from	ADP
admet-2859	63	29	pion	pion	PROPN
admet-2859	63	30	inc	inc	PROPN
admet-2859	63	31	.	.	PROPN
admet-2859	64	1	(	(	PUNCT
admet-2859	64	2	billerica	billerica	PROPN
admet-2859	64	3	,	,	PUNCT
admet-2859	64	4	ma	ma	PROPN
admet-2859	64	5	,	,	PUNCT
admet-2859	64	6	usa	usa	PROPN
admet-2859	64	7	)	)	PUNCT
admet-2859	64	8	,	,	PUNCT
admet-2859	64	9	n	n	CCONJ
admet-2859	64	10	-	-	PUNCT
admet-2859	64	11	dodecane	dodecane	NOUN
admet-2859	64	12	from	from	ADP
admet-2859	64	13	sigma	sigma	PROPN
admet-2859	64	14	-	-	PUNCT
admet-2859	64	15	aldrich	aldrich	PROPN
admet-2859	64	16	(	(	PUNCT
admet-2859	64	17	st	st	PROPN
admet-2859	64	18	.	.	PROPN
admet-2859	64	19	louis	louis	PROPN
admet-2859	64	20	,	,	PUNCT
admet-2859	64	21	missouri	missouri	PROPN
admet-2859	64	22	,	,	PUNCT
admet-2859	64	23	usa	usa	PROPN
admet-2859	64	24	)	)	PUNCT
admet-2859	64	25	and	and	CCONJ
admet-2859	64	26	methanol	methanol	NOUN
admet-2859	64	27	from	from	ADP
admet-2859	64	28	thomasker	thomasker	NOUN
admet-2859	64	29	(	(	PUNCT
admet-2859	64	30	budapest	budapest	ADJ
admet-2859	64	31	,	,	PUNCT
admet-2859	64	32	hungary	hungary	PROPN
admet-2859	64	33	)	)	PUNCT
admet-2859	64	34	.	.	PUNCT
admet-2859	65	1	1	1	NUM
admet-2859	65	2	kda	kda	NOUN
admet-2859	65	3	and	and	CCONJ
admet-2859	65	4	6	6	NUM
admet-2859	65	5	to	to	PART
admet-2859	65	6	8	8	NUM
admet-2859	65	7	kda	kda	NOUN
admet-2859	65	8	regenerated	regenerate	VERB
admet-2859	65	9	cellulose	cellulose	NOUN
admet-2859	65	10	size	size	NOUN
admet-2859	65	11	-	-	PUNCT
admet-2859	65	12	exclusion	exclusion	NOUN
admet-2859	65	13	membranes	membrane	NOUN
admet-2859	65	14	were	be	AUX
admet-2859	65	15	purchased	purchase	VERB
admet-2859	65	16	from	from	ADP
admet-2859	65	17	repligen	repligen	PROPN
admet-2859	65	18	(	(	PUNCT
admet-2859	65	19	boston	boston	PROPN
admet-2859	65	20	,	,	PUNCT
admet-2859	65	21	ma	ma	PROPN
admet-2859	65	22	,	,	PUNCT
admet-2859	65	23	usa	usa	PROPN
admet-2859	65	24	)	)	PUNCT
admet-2859	65	25	.	.	PUNCT
admet-2859	66	1	in	in	ADP
admet-2859	66	2	vitro	vitro	X
admet-2859	66	3	side	side	NOUN
admet-2859	66	4	-	-	PUNCT
admet-2859	66	5	by	by	ADP
admet-2859	66	6	-	-	PUNCT
admet-2859	66	7	side	side	NOUN
admet-2859	66	8	diffusion	diffusion	NOUN
admet-2859	66	9	cell	cell	NOUN
admet-2859	66	10	assays	assay	NOUN
admet-2859	66	11	in	in	ADP
admet-2859	66	12	vitro	vitro	X
admet-2859	66	13	side	side	NOUN
admet-2859	66	14	-	-	PUNCT
admet-2859	66	15	by	by	ADP
admet-2859	66	16	-	-	PUNCT
admet-2859	66	17	side	side	NOUN
admet-2859	66	18	diffusion	diffusion	NOUN
admet-2859	66	19	cell	cell	NOUN
admet-2859	66	20	assays	assay	NOUN
admet-2859	66	21	were	be	AUX
admet-2859	66	22	performed	perform	VERB
admet-2859	66	23	with	with	ADP
admet-2859	66	24	μflux	μflux	NOUN
admet-2859	66	25	(	(	PUNCT
admet-2859	66	26	pion	pion	PROPN
admet-2859	66	27	inc	inc	PROPN
admet-2859	66	28	.	.	PROPN
admet-2859	66	29	,	,	PUNCT
admet-2859	66	30	billerica	billerica	PROPN
admet-2859	66	31	ma	ma	PROPN
admet-2859	66	32	,	,	PUNCT
admet-2859	66	33	usa	usa	PROPN
admet-2859	66	34	)	)	PUNCT
admet-2859	66	35	apparatus	apparatus	NOUN
admet-2859	66	36	.	.	PUNCT
admet-2859	67	1	it	it	PRON
admet-2859	67	2	is	be	AUX
admet-2859	67	3	composed	compose	VERB
admet-2859	67	4	of	of	ADP
admet-2859	67	5	a	a	DET
admet-2859	67	6	donor	donor	NOUN
admet-2859	67	7	and	and	CCONJ
admet-2859	67	8	an	an	DET
admet-2859	67	9	acceptor	acceptor	NOUN
admet-2859	67	10	chamber	chamber	NOUN
admet-2859	67	11	(	(	PUNCT
admet-2859	67	12	20	20	NUM
admet-2859	67	13	ml	ml	PROPN
admet-2859	67	14	volumes	volume	NOUN
admet-2859	67	15	)	)	PUNCT
admet-2859	67	16	separated	separate	VERB
admet-2859	67	17	by	by	ADP
admet-2859	67	18	an	an	DET
admet-2859	67	19	artificial	artificial	ADJ
admet-2859	67	20	membrane	membrane	NOUN
admet-2859	67	21	selected	select	VERB
admet-2859	67	22	to	to	PART
admet-2859	67	23	be	be	AUX
admet-2859	67	24	a	a	DET
admet-2859	67	25	size	size	NOUN
admet-2859	67	26	-	-	PUNCT
admet-2859	67	27	exclusion	exclusion	NOUN
admet-2859	67	28	regenerated	regenerate	VERB
admet-2859	67	29	cellulose	cellulose	NOUN
admet-2859	67	30	membrane	membrane	NOUN
admet-2859	67	31	(	(	PUNCT
admet-2859	67	32	mwco	mwco	NOUN
admet-2859	67	33	6	6	NUM
admet-2859	67	34	kda	kda	NOUN
admet-2859	67	35	and	and	CCONJ
admet-2859	67	36	1	1	NUM
admet-2859	67	37	kda	kda	NOUN
admet-2859	67	38	,	,	PUNCT
admet-2859	67	39	1.54	1.54	NUM
admet-2859	67	40	cm2	cm2	NOUN
admet-2859	67	41	,	,	PUNCT
admet-2859	67	42	)	)	PUNCT
admet-2859	67	43	pre	pre	ADJ
admet-2859	67	44	-	-	VERB
admet-2859	67	45	soaked	soaked	ADJ
admet-2859	67	46	in	in	ADP
admet-2859	67	47	distilled	distil	VERB
admet-2859	67	48	water	water	NOUN
admet-2859	67	49	overnight	overnight	ADV
admet-2859	67	50	prior	prior	ADV
admet-2859	67	51	to	to	ADP
admet-2859	67	52	measurement	measurement	NOUN
admet-2859	67	53	,	,	PUNCT
admet-2859	67	54	and	and	CCONJ
admet-2859	67	55	a	a	DET
admet-2859	67	56	lipophilic	lipophilic	ADJ
admet-2859	67	57	membrane	membrane	NOUN
admet-2859	67	58	(	(	PUNCT
admet-2859	67	59	0.45	0.45	NUM
admet-2859	67	60	µm	µm	ADP
admet-2859	67	61	pore	pore	ADJ
admet-2859	67	62	size	size	NOUN
admet-2859	67	63	pvdf	pvdf	PROPN
admet-2859	67	64	sheet	sheet	NOUN
admet-2859	67	65	,	,	PUNCT
admet-2859	67	66	1.54	1.54	NUM
admet-2859	67	67	cm2	cm2	NOUN
admet-2859	67	68	)	)	PUNCT
admet-2859	67	69	impregnated	impregnate	VERB
admet-2859	67	70	with	with	ADP
admet-2859	67	71	25	25	NUM
admet-2859	67	72	μl	μl	ADJ
admet-2859	67	73	n	n	CCONJ
admet-2859	67	74	-	-	PUNCT
admet-2859	67	75	dodecane	dodecane	NOUN
admet-2859	67	76	.	.	PUNCT
admet-2859	68	1	the	the	DET
admet-2859	68	2	measurements	measurement	NOUN
admet-2859	68	3	were	be	AUX
admet-2859	68	4	performed	perform	VERB
admet-2859	68	5	in	in	ADP
admet-2859	68	6	four	four	NUM
admet-2859	68	7	different	different	ADJ
admet-2859	68	8	arrangements	arrangement	NOUN
admet-2859	68	9	for	for	ADP
admet-2859	68	10	each	each	DET
admet-2859	68	11	membrane	membrane	NOUN
admet-2859	68	12	type	type	NOUN
admet-2859	68	13	,	,	PUNCT
admet-2859	68	14	which	which	PRON
admet-2859	68	15	are	be	AUX
admet-2859	68	16	listed	list	VERB
admet-2859	68	17	in	in	ADP
admet-2859	68	18	table	table	NOUN
admet-2859	68	19	1	1	NUM
admet-2859	68	20	.	.	PUNCT
admet-2859	68	21	table	table	NOUN
admet-2859	68	22	1	1	NUM
admet-2859	68	23	.	.	PUNCT
admet-2859	69	1	in	in	ADP
admet-2859	69	2	vitro	vitro	X
admet-2859	69	3	side	side	NOUN
admet-2859	69	4	-	-	PUNCT
admet-2859	69	5	by	by	ADP
admet-2859	69	6	-	-	PUNCT
admet-2859	69	7	side	side	NOUN
admet-2859	69	8	diffusion	diffusion	NOUN
admet-2859	69	9	cell	cell	NOUN
admet-2859	69	10	assay	assay	PROPN
admet-2859	69	11	measurement	measurement	NOUN
admet-2859	69	12	settings	setting	NOUN
admet-2859	69	13	settings	setting	VERB
admet-2859	69	14	no	no	INTJ
admet-2859	69	15	.	.	PUNCT
admet-2859	70	1	donor	donor	NOUN
admet-2859	70	2	side	side	NOUN
admet-2859	70	3	acceptor	acceptor	NOUN
admet-2859	70	4	side	side	NOUN
admet-2859	70	5	1	1	NUM
admet-2859	70	6	.	.	NOUN
admet-2859	70	7	18	18	NUM
admet-2859	70	8	ml	ml	NOUN
admet-2859	70	9	ph	ph	ADJ
admet-2859	70	10	10	10	NUM
admet-2859	70	11	prisma	prisma	NOUN
admet-2859	70	12	buffer	buffer	NOUN
admet-2859	70	13	18	18	NUM
admet-2859	70	14	ml	ml	ADV
admet-2859	70	15	ph	ph	ADJ
admet-2859	70	16	10	10	NUM
admet-2859	70	17	prisma	prisma	NOUN
admet-2859	70	18	buffer	buffer	NOUN
admet-2859	70	19	2	2	NUM
admet-2859	70	20	.	.	NOUN
admet-2859	70	21	18	18	NUM
admet-2859	70	22	ml	ml	NOUN
admet-2859	70	23	ph	ph	ADJ
admet-2859	70	24	10	10	NUM
admet-2859	70	25	prisma	prisma	NOUN
admet-2859	70	26	buffer	buffer	NOUN
admet-2859	70	27	+	+	CCONJ
admet-2859	70	28	15	15	NUM
admet-2859	70	29	mg	mg	NOUN
admet-2859	70	30	ml-1	ml-1	PRON
admet-2859	70	31	hp	hp	PROPN
admet-2859	70	32	-	-	PUNCT
admet-2859	70	33	β	β	NOUN
admet-2859	70	34	-	-	NOUN
admet-2859	70	35	cd	cd	ADJ
admet-2859	70	36	18	18	NUM
admet-2859	70	37	ml	ml	NOUN
admet-2859	70	38	ph	ph	ADJ
admet-2859	70	39	10	10	NUM
admet-2859	70	40	prisma	prisma	NOUN
admet-2859	70	41	buffer	buffer	NOUN
admet-2859	70	42	3	3	NUM
admet-2859	70	43	.	.	NOUN
admet-2859	70	44	18	18	NUM
admet-2859	70	45	ml	ml	NOUN
admet-2859	70	46	ph	ph	ADJ
admet-2859	70	47	10	10	NUM
admet-2859	70	48	prisma	prisma	NOUN
admet-2859	70	49	buffer	buffer	NOUN
admet-2859	70	50	18	18	NUM
admet-2859	70	51	ml	ml	ADV
admet-2859	70	52	ph	ph	ADJ
admet-2859	70	53	10	10	NUM
admet-2859	70	54	prisma	prisma	NOUN
admet-2859	70	55	buffer	buffer	NOUN
admet-2859	70	56	+	+	CCONJ
admet-2859	70	57	15	15	NUM
admet-2859	70	58	mg	mg	NOUN
admet-2859	70	59	ml-1	ml-1	PRON
admet-2859	70	60	hp	hp	PROPN
admet-2859	70	61	-	-	PUNCT
admet-2859	70	62	β	β	NOUN
admet-2859	70	63	-	-	NOUN
admet-2859	70	64	cd	cd	ADJ
admet-2859	70	65	4	4	NUM
admet-2859	70	66	.	.	NOUN
admet-2859	70	67	18	18	NUM
admet-2859	70	68	ml	ml	NOUN
admet-2859	70	69	ph	ph	ADJ
admet-2859	70	70	10	10	NUM
admet-2859	70	71	prisma	prisma	NOUN
admet-2859	70	72	buffer	buffer	NOUN
admet-2859	70	73	+	+	CCONJ
admet-2859	70	74	15	15	NUM
admet-2859	70	75	mg	mg	NOUN
admet-2859	70	76	ml-1	ml-1	PRON
admet-2859	70	77	hp	hp	PROPN
admet-2859	70	78	-	-	PUNCT
admet-2859	70	79	β	β	NOUN
admet-2859	70	80	-	-	NOUN
admet-2859	70	81	cd	cd	ADJ
admet-2859	70	82	18	18	NUM
admet-2859	70	83	ml	ml	NOUN
admet-2859	70	84	ph	ph	ADJ
admet-2859	70	85	10	10	NUM
admet-2859	70	86	prisma	prisma	NOUN
admet-2859	70	87	buffer	buffer	NOUN
admet-2859	70	88	+	+	CCONJ
admet-2859	70	89	15	15	NUM
admet-2859	70	90	mg	mg	NOUN
admet-2859	70	91	ml-1	ml-1	PRON
admet-2859	70	92	hp	hp	PROPN
admet-2859	70	93	-	-	PUNCT
admet-2859	70	94	β	β	NOUN
admet-2859	70	95	-	-	NOUN
admet-2859	70	96	cd	cd	VERB
admet-2859	70	97	the	the	DET
admet-2859	70	98	appropriate	appropriate	ADJ
admet-2859	70	99	amount	amount	NOUN
admet-2859	70	100	of	of	ADP
admet-2859	70	101	3	3	NUM
admet-2859	70	102	mg	mg	NOUN
admet-2859	70	103	ml-1	ml-1	CCONJ
admet-2859	70	104	methanol	methanol	NOUN
admet-2859	70	105	stock	stock	NOUN
admet-2859	70	106	solution	solution	NOUN
admet-2859	70	107	of	of	ADP
admet-2859	70	108	the	the	DET
admet-2859	70	109	drug	drug	NOUN
admet-2859	70	110	was	be	AUX
admet-2859	70	111	pipetted	pipette	VERB
admet-2859	70	112	to	to	ADP
admet-2859	70	113	the	the	DET
admet-2859	70	114	donor	donor	NOUN
admet-2859	70	115	side	side	NOUN
admet-2859	70	116	.	.	PUNCT
admet-2859	71	1	both	both	DET
admet-2859	71	2	cells	cell	NOUN
admet-2859	71	3	were	be	AUX
admet-2859	71	4	thermostated	thermostat	VERB
admet-2859	71	5	and	and	CCONJ
admet-2859	71	6	stirred	stir	VERB
admet-2859	71	7	at	at	ADP
admet-2859	71	8	250	250	NUM
admet-2859	71	9	rpm	rpm	NOUN
admet-2859	71	10	based	base	VERB
admet-2859	71	11	on	on	ADP
admet-2859	71	12	the	the	DET
admet-2859	71	13	results	result	NOUN
admet-2859	71	14	of	of	ADP
admet-2859	71	15	our	our	PRON
admet-2859	71	16	previous	previous	ADJ
admet-2859	71	17	study	study	NOUN
admet-2859	71	18	,	,	PUNCT
admet-2859	71	19	which	which	PRON
admet-2859	71	20	showed	show	VERB
admet-2859	71	21	that	that	SCONJ
admet-2859	71	22	stirring	stirring	NOUN
admet-2859	71	23	is	be	AUX
admet-2859	71	24	essential	essential	ADJ
admet-2859	71	25	to	to	PART
admet-2859	71	26	investigate	investigate	VERB
admet-2859	71	27	the	the	DET
admet-2859	71	28	effect	effect	NOUN
admet-2859	71	29	of	of	ADP
admet-2859	71	30	excipients	excipient	NOUN
admet-2859	71	31	[	[	X
admet-2859	71	32	1	1	NUM
admet-2859	71	33	]	]	PUNCT
admet-2859	71	34	.	.	PUNCT
admet-2859	72	1	drug	drug	NOUN
admet-2859	72	2	concentrations	concentration	NOUN
admet-2859	72	3	at	at	ADP
admet-2859	72	4	the	the	DET
admet-2859	72	5	donor	donor	NOUN
admet-2859	72	6	and	and	CCONJ
admet-2859	72	7	acceptor	acceptor	NOUN
admet-2859	72	8	sides	side	NOUN
admet-2859	72	9	were	be	AUX
admet-2859	72	10	monitored	monitor	VERB
admet-2859	72	11	in	in	ADP
admet-2859	72	12	real	real	ADJ
admet-2859	72	13	-	-	PUNCT
admet-2859	72	14	time	time	NOUN
admet-2859	72	15	using	use	VERB
admet-2859	72	16	uv	uv	NOUN
admet-2859	72	17	probes	probe	NOUN
admet-2859	72	18	with	with	ADP
admet-2859	72	19	the	the	DET
admet-2859	72	20	rainbow	rainbow	NOUN
admet-2859	72	21	(	(	PUNCT
admet-2859	72	22	pion	pion	PROPN
admet-2859	72	23	inc	inc	PROPN
admet-2859	72	24	.	.	PROPN
admet-2859	72	25	,	,	PUNCT
admet-2859	72	26	billerica	billerica	PROPN
admet-2859	72	27	,	,	PUNCT
admet-2859	72	28	ma	ma	PROPN
admet-2859	72	29	,	,	PUNCT
admet-2859	72	30	usa	usa	PROPN
admet-2859	72	31	)	)	PUNCT
admet-2859	72	32	apparatus	apparatus	NOUN
admet-2859	72	33	.	.	PUNCT
admet-2859	73	1	a	a	DET
admet-2859	73	2	second	second	ADJ
admet-2859	73	3	derivative	derivative	ADJ
admet-2859	73	4	method	method	NOUN
admet-2859	73	5	between	between	ADP
admet-2859	73	6	292	292	NUM
admet-2859	73	7	and	and	CCONJ
admet-2859	73	8	300	300	NUM
admet-2859	73	9	nm	nm	NOUN
admet-2859	73	10	was	be	AUX
admet-2859	73	11	used	use	VERB
admet-2859	73	12	to	to	PART
admet-2859	73	13	evaluate	evaluate	VERB
admet-2859	73	14	the	the	DET
admet-2859	73	15	spectra	spectra	NOUN
admet-2859	73	16	,	,	PUNCT
admet-2859	73	17	and	and	CCONJ
admet-2859	73	18	the	the	DET
admet-2859	73	19	flux	flux	NOUN
admet-2859	73	20	(	(	PUNCT
admet-2859	73	21	j	j	NOUN
admet-2859	73	22	)	)	PUNCT
admet-2859	73	23	and	and	CCONJ
admet-2859	73	24	apparent	apparent	ADJ
admet-2859	73	25	permeability	permeability	NOUN
admet-2859	73	26	(	(	PUNCT
admet-2859	73	27	papp	papp	NOUN
admet-2859	73	28	/	/	SYM
admet-2859	73	29	cm	cm	NOUN
admet-2859	73	30	s-1	s-1	NOUN
admet-2859	73	31	)	)	PUNCT
admet-2859	73	32	were	be	AUX
admet-2859	73	33	calculated	calculate	VERB
admet-2859	73	34	[	[	X
admet-2859	73	35	13	13	NUM
admet-2859	73	36	]	]	PUNCT
admet-2859	73	37	according	accord	VERB
admet-2859	73	38	to	to	ADP
admet-2859	73	39	equation	equation	NOUN
admet-2859	73	40	1	1	NUM
admet-2859	73	41	:	:	PUNCT
admet-2859	73	42	app	app	PROPN
admet-2859	73	43	  	  	SPACE
admet-2859	73	44	d	d	PROPN
admet-2859	74	1	d	d	NOUN
admet-2859	74	2	       	       	SPACE
admet-2859	74	3	n	n	PRON
admet-2859	74	4	j	j	PROPN
admet-2859	74	5	a	a	X
admet-2859	74	6	tp	tp	NOUN
admet-2859	74	7	c	c	PROPN
admet-2859	74	8	c	c	NOUN
admet-2859	74	9			NOUN
admet-2859	74	10	=	=	PROPN
admet-2859	74	11	=	=	SYM
admet-2859	74	12	(	(	PUNCT
admet-2859	74	13	1	1	NUM
admet-2859	74	14	)	)	PUNCT
admet-2859	74	15	where	where	SCONJ
admet-2859	74	16	apparent	apparent	ADJ
admet-2859	74	17	permeability	permeability	NOUN
admet-2859	74	18	(	(	PUNCT
admet-2859	74	19	papp	papp	NOUN
admet-2859	74	20	)	)	PUNCT
admet-2859	74	21	is	be	AUX
admet-2859	74	22	the	the	DET
admet-2859	74	23	quotient	quotient	NOUN
admet-2859	74	24	of	of	ADP
admet-2859	74	25	flux	flux	NOUN
admet-2859	74	26	(	(	PUNCT
admet-2859	74	27	j	j	PROPN
admet-2859	74	28	/	/	SYM
admet-2859	74	29	mol	mol	ADP
admet-2859	74	30	s-1	s-1	PROPN
admet-2859	74	31	cm2	cm2	NOUN
admet-2859	74	32	)	)	PUNCT
admet-2859	74	33	and	and	CCONJ
admet-2859	74	34	donor	donor	NOUN
admet-2859	74	35	-	-	PUNCT
admet-2859	74	36	side	side	NOUN
admet-2859	74	37	concentration	concentration	NOUN
admet-2859	74	38	(	(	PUNCT
admet-2859	74	39	cd	cd	PROPN
admet-2859	74	40	/	/	SYM
admet-2859	74	41	mol	mol	PROPN
admet-2859	74	42	cm-3	cm-3	NOUN
admet-2859	74	43	)	)	PUNCT
admet-2859	74	44	,	,	PUNCT
admet-2859	74	45	flux	flux	NOUN
admet-2859	74	46	(	(	PUNCT
admet-2859	74	47	j	j	NOUN
admet-2859	74	48	)	)	PUNCT
admet-2859	74	49	of	of	ADP
admet-2859	74	50	a	a	DET
admet-2859	74	51	drug	drug	NOUN
admet-2859	74	52	across	across	ADP
admet-2859	74	53	the	the	DET
admet-2859	74	54	membrane	membrane	NOUN
admet-2859	74	55	is	be	AUX
admet-2859	74	56	defined	define	VERB
admet-2859	74	57	as	as	ADP
admet-2859	74	58	the	the	DET
admet-2859	74	59	molar	molar	ADJ
admet-2859	74	60	amount	amount	NOUN
admet-2859	74	61	of	of	ADP
admet-2859	74	62	substance	substance	NOUN
admet-2859	74	63	diffused	diffuse	VERB
admet-2859	74	64	from	from	ADP
admet-2859	74	65	the	the	DET
admet-2859	74	66	donor	donor	NOUN
admet-2859	74	67	to	to	ADP
admet-2859	74	68	the	the	DET
admet-2859	74	69	acceptor	acceptor	NOUN
admet-2859	74	70	compartment	compartment	NOUN
admet-2859	74	71	(	(	PUNCT
admet-2859	74	72	n	n	NOUN
admet-2859	74	73	/	/	SYM
admet-2859	74	74	mol	mol	NOUN
admet-2859	74	75	)	)	PUNCT
admet-2859	74	76	crossing	cross	VERB
admet-2859	74	77	a	a	DET
admet-2859	74	78	unit	unit	NOUN
admet-2859	74	79	area	area	NOUN
admet-2859	74	80	(	(	PUNCT
admet-2859	74	81	a	a	DET
admet-2859	74	82	/	/	SYM
admet-2859	74	83	cm2	cm2	NOUN
admet-2859	74	84	)	)	PUNCT
admet-2859	74	85	perpendicular	perpendicular	NOUN
admet-2859	74	86	to	to	ADP
admet-2859	74	87	its	its	PRON
admet-2859	74	88	flow	flow	NOUN
admet-2859	74	89	admet	admet	NOUN
admet-2859	74	90	&	&	CCONJ
admet-2859	74	91	dmpk	dmpk	PROPN
admet-2859	74	92	13(5	13(5	NOUN
admet-2859	74	93	)	)	PUNCT
admet-2859	74	94	(	(	PUNCT
admet-2859	74	95	2025	2025	NUM
admet-2859	74	96	)	)	PUNCT
admet-2859	74	97	2859	2859	NUM
admet-2859	74	98	comparison	comparison	NOUN
admet-2859	74	99	of	of	ADP
admet-2859	74	100	lipophilic	lipophilic	ADJ
admet-2859	74	101	and	and	CCONJ
admet-2859	74	102	size	size	NOUN
admet-2859	74	103	-	-	PUNCT
admet-2859	74	104	exclusion	exclusion	NOUN
admet-2859	74	105	membranes	membrane	NOUN
admet-2859	74	106	doi	doi	NOUN
admet-2859	74	107	:	:	PUNCT
admet-2859	74	108	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	X
admet-2859	74	109	5	5	NUM
admet-2859	74	110	per	per	ADP
admet-2859	74	111	unit	unit	NOUN
admet-2859	74	112	time	time	NOUN
admet-2859	74	113	(	(	PUNCT
admet-2859	74	114	t	t	PROPN
admet-2859	74	115	/	/	SYM
admet-2859	74	116	s	s	PROPN
admet-2859	74	117	)	)	PUNCT
admet-2859	74	118	.	.	PUNCT
admet-2859	75	1	results	result	NOUN
admet-2859	75	2	and	and	CCONJ
admet-2859	75	3	discussion	discussion	NOUN
admet-2859	75	4	this	this	DET
admet-2859	75	5	work	work	NOUN
admet-2859	75	6	investigates	investigate	VERB
admet-2859	75	7	the	the	DET
admet-2859	75	8	effect	effect	NOUN
admet-2859	75	9	of	of	ADP
admet-2859	75	10	sink	sink	NOUN
admet-2859	75	11	condition	condition	NOUN
admet-2859	75	12	across	across	ADP
admet-2859	75	13	three	three	NUM
admet-2859	75	14	distinct	distinct	ADJ
admet-2859	75	15	membrane	membrane	NOUN
admet-2859	75	16	types	type	NOUN
admet-2859	75	17	(	(	PUNCT
admet-2859	75	18	pvdf	pvdf	NOUN
admet-2859	75	19	filter	filter	NOUN
admet-2859	75	20	impregnated	impregnate	VERB
admet-2859	75	21	with	with	ADP
admet-2859	75	22	n	n	NOUN
admet-2859	75	23	-	-	PUNCT
admet-2859	75	24	dodecane	dodecane	NOUN
admet-2859	75	25	and	and	CCONJ
admet-2859	75	26	two	two	NUM
admet-2859	75	27	size	size	NOUN
admet-2859	75	28	-	-	PUNCT
admet-2859	75	29	exclusion	exclusion	NOUN
admet-2859	75	30	membranes	membrane	NOUN
admet-2859	75	31	mwco	mwco	NOUN
admet-2859	75	32	=	=	SYM
admet-2859	75	33	1	1	NUM
admet-2859	75	34	and	and	CCONJ
admet-2859	75	35	6	6	NUM
admet-2859	75	36	kda	kda	NOUN
admet-2859	75	37	)	)	PUNCT
admet-2859	75	38	.	.	PUNCT
admet-2859	76	1	for	for	ADP
admet-2859	76	2	that	that	PRON
admet-2859	76	3	,	,	PUNCT
admet-2859	76	4	solubility	solubility	NOUN
admet-2859	76	5	measurements	measurement	NOUN
admet-2859	76	6	were	be	AUX
admet-2859	76	7	carried	carry	VERB
admet-2859	76	8	out	out	ADP
admet-2859	76	9	to	to	PART
admet-2859	76	10	see	see	VERB
admet-2859	76	11	if	if	SCONJ
admet-2859	76	12	hp	hp	ADJ
admet-2859	76	13	-	-	PUNCT
admet-2859	76	14	β	β	NOUN
admet-2859	76	15	-	-	NOUN
admet-2859	76	16	cd	cd	NOUN
admet-2859	76	17	can	can	AUX
admet-2859	76	18	truly	truly	ADV
admet-2859	76	19	create	create	VERB
admet-2859	76	20	a	a	DET
admet-2859	76	21	sink	sink	NOUN
admet-2859	76	22	condition	condition	NOUN
admet-2859	76	23	for	for	ADP
admet-2859	76	24	the	the	DET
admet-2859	76	25	model	model	NOUN
admet-2859	76	26	drug	drug	NOUN
admet-2859	76	27	car	car	NOUN
admet-2859	76	28	(	(	PUNCT
admet-2859	76	29	see	see	VERB
admet-2859	76	30	detailed	detailed	ADJ
admet-2859	76	31	results	result	NOUN
admet-2859	76	32	in	in	ADP
admet-2859	76	33	the	the	DET
admet-2859	76	34	previous	previous	ADJ
admet-2859	76	35	publication	publication	NOUN
admet-2859	76	36	[	[	X
admet-2859	76	37	1	1	NUM
admet-2859	76	38	]	]	NUM
admet-2859	76	39	)	)	PUNCT
admet-2859	76	40	.	.	PUNCT
admet-2859	77	1	the	the	DET
admet-2859	77	2	concentration	concentration	NOUN
admet-2859	77	3	of	of	ADP
admet-2859	77	4	the	the	DET
admet-2859	77	5	solubilizing	solubilize	VERB
admet-2859	77	6	additive	additive	NOUN
admet-2859	77	7	was	be	AUX
admet-2859	77	8	chosen	choose	VERB
admet-2859	77	9	based	base	VERB
admet-2859	77	10	on	on	ADP
admet-2859	77	11	a	a	DET
admet-2859	77	12	known	know	VERB
admet-2859	77	13	hp	hp	NOUN
admet-2859	77	14	-	-	PUNCT
admet-2859	77	15	β	β	NOUN
admet-2859	77	16	-	-	NOUN
admet-2859	77	17	cd	cd	NOUN
admet-2859	77	18	containing	contain	VERB
admet-2859	77	19	marketed	market	VERB
admet-2859	77	20	solution	solution	NOUN
admet-2859	77	21	[	[	X
admet-2859	77	22	45	45	NUM
admet-2859	77	23	]	]	PUNCT
admet-2859	77	24	and	and	CCONJ
admet-2859	77	25	the	the	DET
admet-2859	77	26	recommendation	recommendation	NOUN
admet-2859	77	27	to	to	PART
admet-2859	77	28	take	take	VERB
admet-2859	77	29	the	the	DET
admet-2859	77	30	solution	solution	NOUN
admet-2859	77	31	with	with	ADP
admet-2859	77	32	a	a	DET
admet-2859	77	33	glass	glass	NOUN
admet-2859	77	34	of	of	ADP
admet-2859	77	35	water	water	NOUN
admet-2859	77	36	.	.	PUNCT
admet-2859	78	1	the	the	DET
admet-2859	78	2	thermodynamic	thermodynamic	ADJ
admet-2859	78	3	solubility	solubility	NOUN
admet-2859	78	4	results	result	VERB
admet-2859	78	5	with	with	ADP
admet-2859	78	6	the	the	DET
admet-2859	78	7	chosen	choose	VERB
admet-2859	78	8	15	15	NUM
admet-2859	78	9	mg	mg	PROPN
admet-2859	78	10	ml-1	ml-1	PRON
admet-2859	78	11	hp	hp	PROPN
admet-2859	78	12	-	-	PUNCT
admet-2859	78	13	β	β	NOUN
admet-2859	78	14	-	-	ADJ
admet-2859	78	15	cd	cd	ADJ
admet-2859	78	16	concentration	concentration	NOUN
admet-2859	78	17	showed	show	VERB
admet-2859	78	18	three	three	NUM
admet-2859	78	19	times	time	NOUN
admet-2859	78	20	higher	high	ADJ
admet-2859	78	21	value	value	NOUN
admet-2859	78	22	than	than	ADP
admet-2859	78	23	the	the	DET
admet-2859	78	24	solubility	solubility	NOUN
admet-2859	78	25	of	of	ADP
admet-2859	78	26	the	the	DET
admet-2859	78	27	pure	pure	ADJ
admet-2859	78	28	api	api	NOUN
admet-2859	78	29	in	in	ADP
admet-2859	78	30	plain	plain	ADJ
admet-2859	78	31	ph	ph	ADJ
admet-2859	78	32	10	10	NUM
admet-2859	78	33	buffer	buffer	NOUN
admet-2859	79	1	[	[	X
admet-2859	79	2	1	1	NUM
admet-2859	79	3	]	]	PUNCT
admet-2859	79	4	.	.	PUNCT
admet-2859	80	1	the	the	DET
admet-2859	80	2	fundamental	fundamental	ADJ
admet-2859	80	3	difference	difference	NOUN
admet-2859	80	4	between	between	ADP
admet-2859	80	5	the	the	DET
admet-2859	80	6	membrane	membrane	NOUN
admet-2859	80	7	types	type	NOUN
admet-2859	80	8	is	be	AUX
admet-2859	80	9	that	that	SCONJ
admet-2859	80	10	in	in	ADP
admet-2859	80	11	the	the	DET
admet-2859	80	12	case	case	NOUN
admet-2859	80	13	of	of	ADP
admet-2859	80	14	the	the	DET
admet-2859	80	15	lipophilic	lipophilic	ADJ
admet-2859	80	16	membrane	membrane	NOUN
admet-2859	80	17	,	,	PUNCT
admet-2859	80	18	only	only	ADV
admet-2859	80	19	the	the	DET
admet-2859	80	20	drug	drug	NOUN
admet-2859	80	21	can	can	AUX
admet-2859	80	22	permeate	permeate	VERB
admet-2859	80	23	the	the	DET
admet-2859	80	24	membrane	membrane	NOUN
admet-2859	80	25	[	[	X
admet-2859	80	26	1	1	NUM
admet-2859	80	27	]	]	PUNCT
admet-2859	80	28	,	,	PUNCT
admet-2859	80	29	while	while	SCONJ
admet-2859	80	30	the	the	DET
admet-2859	80	31	solubilizing	solubilize	VERB
admet-2859	80	32	agent	agent	NOUN
admet-2859	80	33	and	and	CCONJ
admet-2859	80	34	the	the	DET
admet-2859	80	35	drug	drug	NOUN
admet-2859	80	36	-	-	PUNCT
admet-2859	80	37	cd	cd	NOUN
admet-2859	80	38	complex	complex	NOUN
admet-2859	80	39	can	can	AUX
admet-2859	80	40	not	not	PART
admet-2859	80	41	.	.	PUNCT
admet-2859	81	1	in	in	ADP
admet-2859	81	2	contrast	contrast	NOUN
admet-2859	81	3	,	,	PUNCT
admet-2859	81	4	when	when	SCONJ
admet-2859	81	5	using	use	VERB
admet-2859	81	6	size	size	NOUN
admet-2859	81	7	-	-	PUNCT
admet-2859	81	8	exclusion	exclusion	NOUN
admet-2859	81	9	membranes	membrane	NOUN
admet-2859	81	10	,	,	PUNCT
admet-2859	81	11	both	both	CCONJ
admet-2859	81	12	the	the	DET
admet-2859	81	13	drug	drug	NOUN
admet-2859	81	14	and	and	CCONJ
admet-2859	81	15	the	the	DET
admet-2859	81	16	hp	hp	PROPN
admet-2859	81	17	-	-	PUNCT
admet-2859	81	18	β	β	NOUN
admet-2859	81	19	-	-	NOUN
admet-2859	81	20	cd	cd	NOUN
admet-2859	81	21	,	,	PUNCT
admet-2859	81	22	as	as	ADV
admet-2859	81	23	well	well	ADV
admet-2859	81	24	as	as	ADP
admet-2859	81	25	their	their	PRON
admet-2859	81	26	complex	complex	NOUN
admet-2859	81	27	,	,	PUNCT
admet-2859	81	28	can	can	AUX
admet-2859	81	29	permeate	permeate	VERB
admet-2859	81	30	.	.	PUNCT
admet-2859	82	1	the	the	DET
admet-2859	82	2	transport	transport	NOUN
admet-2859	82	3	was	be	AUX
admet-2859	82	4	found	find	VERB
admet-2859	82	5	1.4	1.4	NUM
admet-2859	82	6	times	time	NOUN
admet-2859	82	7	faster	fast	ADV
admet-2859	82	8	in	in	ADP
admet-2859	82	9	the	the	DET
admet-2859	82	10	case	case	NOUN
admet-2859	82	11	of	of	ADP
admet-2859	82	12	the	the	DET
admet-2859	82	13	6	6	NUM
admet-2859	82	14	kda	kda	NOUN
admet-2859	82	15	than	than	ADP
admet-2859	82	16	in	in	ADP
admet-2859	82	17	the	the	DET
admet-2859	82	18	case	case	NOUN
admet-2859	82	19	of	of	ADP
admet-2859	82	20	the	the	DET
admet-2859	82	21	1	1	NUM
admet-2859	82	22	kda	kda	NOUN
admet-2859	82	23	mwco	mwco	NOUN
admet-2859	82	24	membrane	membrane	NOUN
admet-2859	82	25	[	[	X
admet-2859	82	26	1	1	NUM
admet-2859	82	27	]	]	PUNCT
admet-2859	82	28	.	.	PUNCT
admet-2859	83	1	in	in	ADP
admet-2859	83	2	vitro	vitro	X
admet-2859	83	3	side	side	NOUN
admet-2859	83	4	-	-	PUNCT
admet-2859	83	5	by	by	ADP
admet-2859	83	6	-	-	PUNCT
admet-2859	83	7	side	side	NOUN
admet-2859	83	8	diffusion	diffusion	NOUN
admet-2859	83	9	cell	cell	NOUN
admet-2859	83	10	assay	assay	VERB
admet-2859	83	11	considering	consider	VERB
admet-2859	83	12	the	the	DET
admet-2859	83	13	apparent	apparent	ADJ
admet-2859	83	14	permeability	permeability	NOUN
admet-2859	83	15	-	-	PUNCT
admet-2859	83	16	ph	ph	NOUN
admet-2859	83	17	profile	profile	NOUN
admet-2859	83	18	of	of	ADP
admet-2859	83	19	car	car	NOUN
admet-2859	84	1	[	[	X
admet-2859	84	2	1	1	NUM
admet-2859	84	3	]	]	PUNCT
admet-2859	84	4	,	,	PUNCT
admet-2859	84	5	ph	ph	X
admet-2859	84	6	10	10	NUM
admet-2859	84	7	media	medium	NOUN
admet-2859	84	8	was	be	AUX
admet-2859	84	9	chosen	choose	VERB
admet-2859	84	10	for	for	ADP
admet-2859	84	11	the	the	DET
admet-2859	84	12	in	in	NOUN
admet-2859	84	13	vitro	vitro	X
admet-2859	84	14	sideby	sideby	ADJ
admet-2859	84	15	-	-	PUNCT
admet-2859	84	16	side	side	NOUN
admet-2859	84	17	diffusion	diffusion	NOUN
admet-2859	84	18	cell	cell	NOUN
admet-2859	84	19	assays	assay	NOUN
admet-2859	84	20	to	to	PART
admet-2859	84	21	create	create	VERB
admet-2859	84	22	uwl	uwl	ADV
admet-2859	84	23	-	-	PUNCT
admet-2859	84	24	limited	limit	VERB
admet-2859	84	25	transport	transport	NOUN
admet-2859	84	26	conditions	condition	NOUN
admet-2859	84	27	when	when	SCONJ
admet-2859	84	28	a	a	DET
admet-2859	84	29	lipophilic	lipophilic	ADJ
admet-2859	84	30	membrane	membrane	NOUN
admet-2859	84	31	is	be	AUX
admet-2859	84	32	used	use	VERB
admet-2859	84	33	in	in	ADP
admet-2859	84	34	the	the	DET
admet-2859	84	35	absence	absence	NOUN
admet-2859	84	36	of	of	ADP
admet-2859	84	37	hp	hp	PROPN
admet-2859	84	38	-	-	PUNCT
admet-2859	84	39	β	β	NOUN
admet-2859	84	40	-	-	NOUN
admet-2859	84	41	cd	cd	NOUN
admet-2859	84	42	.	.	PUNCT
admet-2859	85	1	the	the	DET
admet-2859	85	2	previous	previous	ADJ
admet-2859	85	3	study	study	NOUN
admet-2859	85	4	also	also	ADV
admet-2859	85	5	revealed	reveal	VERB
admet-2859	85	6	that	that	SCONJ
admet-2859	85	7	the	the	DET
admet-2859	85	8	effect	effect	NOUN
admet-2859	85	9	of	of	ADP
admet-2859	85	10	complexing	complexe	VERB
admet-2859	85	11	agents	agent	NOUN
admet-2859	85	12	can	can	AUX
admet-2859	85	13	be	be	AUX
admet-2859	85	14	better	well	ADV
admet-2859	85	15	characterized	characterize	VERB
admet-2859	85	16	at	at	ADP
admet-2859	85	17	stirred	stir	VERB
admet-2859	85	18	conditions	condition	NOUN
admet-2859	85	19	compared	compare	VERB
admet-2859	85	20	to	to	ADP
admet-2859	85	21	a	a	DET
admet-2859	85	22	non	non	ADJ
admet-2859	85	23	-	-	ADJ
admet-2859	85	24	stirred	stirred	ADJ
admet-2859	85	25	environment	environment	NOUN
admet-2859	85	26	;	;	PUNCT
admet-2859	85	27	therefore	therefore	ADV
admet-2859	85	28	,	,	PUNCT
admet-2859	85	29	250	250	NUM
admet-2859	85	30	rpm	rpm	NOUN
admet-2859	85	31	stirring	stirring	NOUN
admet-2859	85	32	was	be	AUX
admet-2859	85	33	chosen	choose	VERB
admet-2859	85	34	for	for	ADP
admet-2859	85	35	the	the	DET
admet-2859	85	36	following	follow	VERB
admet-2859	85	37	diffusion	diffusion	NOUN
admet-2859	85	38	cell	cell	NOUN
admet-2859	85	39	assays	assay	NOUN
admet-2859	86	1	[	[	X
admet-2859	86	2	1	1	NUM
admet-2859	86	3	]	]	PUNCT
admet-2859	86	4	.	.	PUNCT
admet-2859	87	1	figure	figure	NOUN
admet-2859	87	2	2	2	NUM
admet-2859	87	3	shows	show	VERB
admet-2859	87	4	examples	example	NOUN
admet-2859	87	5	of	of	ADP
admet-2859	87	6	concentration	concentration	NOUN
admet-2859	87	7	-	-	PUNCT
admet-2859	87	8	time	time	NOUN
admet-2859	87	9	profiles	profile	NOUN
admet-2859	87	10	to	to	PART
admet-2859	87	11	present	present	VERB
admet-2859	87	12	the	the	DET
admet-2859	87	13	measurement	measurement	NOUN
admet-2859	87	14	results	result	VERB
admet-2859	87	15	for	for	ADP
admet-2859	87	16	three	three	NUM
admet-2859	87	17	different	different	ADJ
admet-2859	87	18	targeted	target	VERB
admet-2859	87	19	donor	donor	NOUN
admet-2859	87	20	concentrations	concentration	NOUN
admet-2859	87	21	in	in	ADP
admet-2859	87	22	the	the	DET
admet-2859	87	23	donor	donor	NOUN
admet-2859	87	24	and	and	CCONJ
admet-2859	87	25	acceptor	acceptor	NOUN
admet-2859	87	26	compartments	compartment	NOUN
admet-2859	87	27	for	for	ADP
admet-2859	87	28	lipophilic	lipophilic	ADJ
admet-2859	87	29	membrane	membrane	NOUN
admet-2859	87	30	,	,	PUNCT
admet-2859	87	31	1	1	NUM
admet-2859	87	32	and	and	CCONJ
admet-2859	87	33	6	6	NUM
admet-2859	87	34	kda	kda	NOUN
admet-2859	87	35	membranes	membrane	NOUN
admet-2859	87	36	.	.	PUNCT
admet-2859	88	1	donor	donor	NOUN
admet-2859	88	2	concentration	concentration	NOUN
admet-2859	88	3	curves	curve	NOUN
admet-2859	88	4	exhibit	exhibit	VERB
admet-2859	88	5	a	a	DET
admet-2859	88	6	linear	linear	ADJ
admet-2859	88	7	decline	decline	NOUN
admet-2859	88	8	as	as	SCONJ
admet-2859	88	9	the	the	DET
admet-2859	88	10	api	api	NOUN
admet-2859	88	11	is	be	AUX
admet-2859	88	12	transported	transport	VERB
admet-2859	88	13	to	to	ADP
admet-2859	88	14	the	the	DET
admet-2859	88	15	acceptor	acceptor	NOUN
admet-2859	88	16	side	side	NOUN
admet-2859	88	17	.	.	PUNCT
admet-2859	89	1	thermodynamic	thermodynamic	ADJ
admet-2859	89	2	solubility	solubility	NOUN
admet-2859	89	3	of	of	ADP
admet-2859	89	4	car	car	NOUN
admet-2859	89	5	form	form	NOUN
admet-2859	89	6	i	i	PRON
admet-2859	89	7	is	be	AUX
admet-2859	89	8	2.15	2.15	NUM
admet-2859	89	9	µg	µg	NOUN
admet-2859	89	10	ml-1	ml-1	ADV
admet-2859	89	11	in	in	ADP
admet-2859	89	12	plain	plain	ADJ
admet-2859	89	13	ph	ph	ADJ
admet-2859	89	14	10	10	NUM
admet-2859	89	15	buffer	buffer	NOUN
admet-2859	89	16	,	,	PUNCT
admet-2859	89	17	6.69	6.69	NUM
admet-2859	89	18	µg	µg	NOUN
admet-2859	89	19	ml-1	ml-1	ADV
admet-2859	89	20	in	in	ADP
admet-2859	89	21	hp	hp	PROPN
admet-2859	89	22	-	-	PUNCT
admet-2859	89	23	β	β	NOUN
admet-2859	89	24	-	-	ADJ
admet-2859	89	25	cd	cd	ADJ
admet-2859	89	26	containing	contain	VERB
admet-2859	89	27	buffer	buffer	NOUN
admet-2859	89	28	[	[	X
admet-2859	89	29	1	1	NUM
admet-2859	89	30	]	]	PUNCT
admet-2859	89	31	.	.	PUNCT
admet-2859	90	1	the	the	DET
admet-2859	90	2	api	api	NOUN
admet-2859	90	3	was	be	AUX
admet-2859	90	4	introduced	introduce	VERB
admet-2859	90	5	to	to	ADP
admet-2859	90	6	the	the	DET
admet-2859	90	7	donor	donor	NOUN
admet-2859	90	8	side	side	NOUN
admet-2859	90	9	from	from	ADP
admet-2859	90	10	a	a	DET
admet-2859	90	11	methanol	methanol	NOUN
admet-2859	90	12	stock	stock	NOUN
admet-2859	90	13	solution	solution	NOUN
admet-2859	90	14	and	and	CCONJ
admet-2859	90	15	given	give	VERB
admet-2859	90	16	that	that	SCONJ
admet-2859	90	17	the	the	DET
admet-2859	90	18	concentration	concentration	NOUN
admet-2859	90	19	of	of	ADP
admet-2859	90	20	the	the	DET
admet-2859	90	21	api	api	NOUN
admet-2859	90	22	varies	vary	VERB
admet-2859	90	23	from	from	ADP
admet-2859	90	24	0	0	NUM
admet-2859	90	25	to	to	ADP
admet-2859	90	26	25	25	NUM
admet-2859	90	27	µg	µg	ADV
admet-2859	90	28	ml-1	ml-1	X
admet-2859	90	29	,	,	PUNCT
admet-2859	90	30	in	in	ADP
admet-2859	90	31	most	most	ADJ
admet-2859	90	32	experiments	experiment	NOUN
admet-2859	90	33	,	,	PUNCT
admet-2859	90	34	the	the	DET
admet-2859	90	35	donor	donor	NOUN
admet-2859	90	36	concentration	concentration	NOUN
admet-2859	90	37	exceeded	exceed	VERB
admet-2859	90	38	the	the	DET
admet-2859	90	39	thermodynamic	thermodynamic	ADJ
admet-2859	90	40	solubility	solubility	NOUN
admet-2859	90	41	;	;	PUNCT
admet-2859	90	42	therefore	therefore	ADV
admet-2859	90	43	,	,	PUNCT
admet-2859	90	44	supersaturated	supersaturated	ADJ
admet-2859	90	45	solutions	solution	NOUN
admet-2859	90	46	of	of	ADP
admet-2859	90	47	car	car	NOUN
admet-2859	90	48	were	be	AUX
admet-2859	90	49	created	create	VERB
admet-2859	90	50	in	in	ADP
admet-2859	90	51	the	the	DET
admet-2859	90	52	donor	donor	NOUN
admet-2859	90	53	compartment	compartment	NOUN
admet-2859	90	54	.	.	PUNCT
admet-2859	91	1	in	in	ADP
admet-2859	91	2	certain	certain	ADJ
admet-2859	91	3	cases	case	NOUN
admet-2859	91	4	(	(	PUNCT
admet-2859	91	5	figure	figure	NOUN
admet-2859	91	6	2a	2a	NUM
admet-2859	91	7	)	)	PUNCT
admet-2859	91	8	,	,	PUNCT
admet-2859	91	9	the	the	DET
admet-2859	91	10	api	api	NOUN
admet-2859	91	11	precipitated	precipitate	VERB
admet-2859	91	12	from	from	ADP
admet-2859	91	13	these	these	DET
admet-2859	91	14	supersaturated	supersaturated	ADJ
admet-2859	91	15	solutions	solution	NOUN
admet-2859	91	16	(	(	PUNCT
admet-2859	91	17	figure	figure	NOUN
admet-2859	91	18	2	2	NUM
admet-2859	91	19	)	)	PUNCT
admet-2859	91	20	,	,	PUNCT
admet-2859	91	21	resulting	result	VERB
admet-2859	91	22	in	in	ADP
admet-2859	91	23	a	a	DET
admet-2859	91	24	rapid	rapid	ADJ
admet-2859	91	25	decline	decline	NOUN
admet-2859	91	26	in	in	ADP
admet-2859	91	27	both	both	CCONJ
admet-2859	91	28	the	the	DET
admet-2859	91	29	donor	donor	NOUN
admet-2859	91	30	concentration	concentration	NOUN
admet-2859	91	31	and	and	CCONJ
admet-2859	91	32	the	the	DET
admet-2859	91	33	slope	slope	NOUN
admet-2859	91	34	of	of	ADP
admet-2859	91	35	the	the	DET
admet-2859	91	36	acceptor	acceptor	NOUN
admet-2859	91	37	concentration	concentration	NOUN
admet-2859	91	38	-	-	PUNCT
admet-2859	91	39	time	time	NOUN
admet-2859	91	40	curve	curve	NOUN
admet-2859	91	41	.	.	PUNCT
admet-2859	92	1	the	the	DET
admet-2859	92	2	curves	curve	NOUN
admet-2859	92	3	on	on	ADP
admet-2859	92	4	the	the	DET
admet-2859	92	5	acceptor	acceptor	NOUN
admet-2859	92	6	side	side	NOUN
admet-2859	92	7	predominantly	predominantly	ADV
admet-2859	92	8	exhibit	exhibit	VERB
admet-2859	92	9	linearity	linearity	NOUN
admet-2859	92	10	,	,	PUNCT
admet-2859	92	11	with	with	ADP
admet-2859	92	12	a	a	DET
admet-2859	92	13	substantial	substantial	ADJ
admet-2859	92	14	reduction	reduction	NOUN
admet-2859	92	15	in	in	ADP
admet-2859	92	16	the	the	DET
admet-2859	92	17	slope	slope	NOUN
admet-2859	92	18	observable	observable	ADJ
admet-2859	92	19	solely	solely	ADV
admet-2859	92	20	during	during	ADP
admet-2859	92	21	precipitation	precipitation	NOUN
admet-2859	92	22	on	on	ADP
admet-2859	92	23	the	the	DET
admet-2859	92	24	donor	donor	NOUN
admet-2859	92	25	side	side	NOUN
admet-2859	92	26	.	.	PUNCT
admet-2859	93	1	flux	flux	PROPN
admet-2859	93	2	was	be	AUX
admet-2859	93	3	calculated	calculate	VERB
admet-2859	93	4	from	from	ADP
admet-2859	93	5	the	the	DET
admet-2859	93	6	slopes	slope	NOUN
admet-2859	93	7	of	of	ADP
admet-2859	93	8	the	the	DET
admet-2859	93	9	lines	line	NOUN
admet-2859	93	10	fitted	fit	VERB
admet-2859	93	11	to	to	ADP
admet-2859	93	12	their	their	PRON
admet-2859	93	13	initial	initial	ADJ
admet-2859	93	14	linear	linear	ADJ
admet-2859	93	15	phases	phase	NOUN
admet-2859	93	16	.	.	PUNCT
admet-2859	94	1	the	the	DET
admet-2859	94	2	flux	flux	NOUN
admet-2859	94	3	values	value	NOUN
admet-2859	94	4	obtained	obtain	VERB
admet-2859	94	5	from	from	ADP
admet-2859	94	6	in	in	ADP
admet-2859	94	7	vitro	vitro	X
admet-2859	94	8	side	side	NOUN
admet-2859	94	9	-	-	PUNCT
admet-2859	94	10	by	by	ADP
admet-2859	94	11	-	-	PUNCT
admet-2859	94	12	side	side	NOUN
admet-2859	94	13	diffusion	diffusion	NOUN
admet-2859	94	14	cell	cell	NOUN
admet-2859	94	15	assays	assay	NOUN
admet-2859	94	16	measurements	measurement	NOUN
admet-2859	94	17	were	be	AUX
admet-2859	94	18	plotted	plot	VERB
admet-2859	94	19	as	as	ADP
admet-2859	94	20	a	a	DET
admet-2859	94	21	function	function	NOUN
admet-2859	94	22	of	of	ADP
admet-2859	94	23	car	car	NOUN
admet-2859	94	24	concentration	concentration	NOUN
admet-2859	94	25	in	in	ADP
admet-2859	94	26	the	the	DET
admet-2859	94	27	donor	donor	NOUN
admet-2859	94	28	compartment	compartment	NOUN
admet-2859	94	29	(	(	PUNCT
admet-2859	94	30	figure	figure	NOUN
admet-2859	94	31	3	3	NUM
admet-2859	94	32	)	)	PUNCT
admet-2859	94	33	.	.	PUNCT
admet-2859	95	1	figure	figure	VERB
admet-2859	95	2	3	3	NUM
admet-2859	95	3	shows	show	VERB
admet-2859	95	4	that	that	SCONJ
admet-2859	95	5	the	the	DET
admet-2859	95	6	addition	addition	NOUN
admet-2859	95	7	of	of	ADP
admet-2859	95	8	cd	cd	PROPN
admet-2859	95	9	to	to	ADP
admet-2859	95	10	the	the	DET
admet-2859	95	11	acceptor	acceptor	NOUN
admet-2859	95	12	solution	solution	NOUN
admet-2859	95	13	results	result	VERB
admet-2859	95	14	in	in	ADP
admet-2859	95	15	a	a	DET
admet-2859	95	16	modest	modest	ADJ
admet-2859	95	17	increase	increase	NOUN
admet-2859	95	18	in	in	ADP
admet-2859	95	19	the	the	DET
admet-2859	95	20	slope	slope	NOUN
admet-2859	95	21	of	of	ADP
admet-2859	95	22	the	the	DET
admet-2859	95	23	flux	flux	NOUN
admet-2859	95	24	curve	curve	NOUN
admet-2859	95	25	when	when	SCONJ
admet-2859	95	26	comparing	compare	VERB
admet-2859	95	27	the	the	DET
admet-2859	95	28	‘	'	PUNCT
admet-2859	95	29	cdacceptor	cdacceptor	NOUN
admet-2859	95	30	’	'	PUNCT
admet-2859	95	31	curve	curve	NOUN
admet-2859	95	32	to	to	ADP
admet-2859	95	33	the	the	DET
admet-2859	95	34	‘	'	PUNCT
admet-2859	95	35	cd	cd	NOUN
admet-2859	95	36	-	-	PUNCT
admet-2859	95	37	none	none	NOUN
admet-2859	95	38	’	'	PUNCT
admet-2859	95	39	curve	curve	NOUN
admet-2859	95	40	,	,	PUNCT
admet-2859	95	41	and	and	CCONJ
admet-2859	95	42	the	the	DET
admet-2859	95	43	‘	'	PUNCT
admet-2859	95	44	cd	cd	NOUN
admet-2859	95	45	-	-	PUNCT
admet-2859	95	46	both	both	PRON
admet-2859	95	47	’	'	PUNCT
admet-2859	95	48	curve	curve	NOUN
admet-2859	95	49	to	to	ADP
admet-2859	95	50	the	the	DET
admet-2859	95	51	‘	'	PUNCT
admet-2859	95	52	cd	cd	NOUN
admet-2859	95	53	-	-	PUNCT
admet-2859	95	54	donor	donor	NOUN
admet-2859	95	55	’	'	PUNCT
admet-2859	95	56	curve	curve	NOUN
admet-2859	95	57	across	across	ADP
admet-2859	95	58	all	all	DET
admet-2859	95	59	three	three	NUM
admet-2859	95	60	membrane	membrane	ADJ
admet-2859	95	61	types	type	NOUN
admet-2859	95	62	,	,	PUNCT
admet-2859	95	63	attributable	attributable	ADJ
admet-2859	95	64	to	to	PART
admet-2859	95	65	sink	sink	VERB
admet-2859	95	66	condition	condition	NOUN
admet-2859	95	67	.	.	PUNCT
admet-2859	96	1	the	the	DET
admet-2859	96	2	slope	slope	NOUN
admet-2859	96	3	of	of	ADP
admet-2859	96	4	the	the	DET
admet-2859	96	5	flux	flux	NOUN
admet-2859	96	6	-	-	PUNCT
admet-2859	96	7	donor	donor	NOUN
admet-2859	96	8	concentration	concentration	NOUN
admet-2859	96	9	line	line	NOUN
admet-2859	96	10	is	be	AUX
admet-2859	96	11	directly	directly	ADV
admet-2859	96	12	proportional	proportional	ADJ
admet-2859	96	13	to	to	ADP
admet-2859	96	14	the	the	DET
admet-2859	96	15	permeability	permeability	NOUN
admet-2859	96	16	value	value	NOUN
admet-2859	96	17	,	,	PUNCT
admet-2859	96	18	which	which	PRON
admet-2859	96	19	was	be	AUX
admet-2859	96	20	calculated	calculate	VERB
admet-2859	96	21	and	and	CCONJ
admet-2859	96	22	plotted	plot	VERB
admet-2859	96	23	in	in	ADP
admet-2859	96	24	figure	figure	NOUN
admet-2859	96	25	4	4	NUM
admet-2859	96	26	.	.	PUNCT
admet-2859	97	1	the	the	DET
admet-2859	97	2	sink	sink	NOUN
admet-2859	97	3	effect	effect	NOUN
admet-2859	97	4	is	be	AUX
admet-2859	97	5	significant	significant	ADJ
admet-2859	97	6	using	use	VERB
admet-2859	97	7	a	a	DET
admet-2859	97	8	lipophilic	lipophilic	ADJ
admet-2859	97	9	membrane	membrane	NOUN
admet-2859	97	10	(	(	PUNCT
admet-2859	97	11	see	see	VERB
admet-2859	97	12	table	table	NOUN
admet-2859	97	13	2	2	NUM
admet-2859	97	14	for	for	ADP
admet-2859	97	15	the	the	DET
admet-2859	97	16	homogeneity	homogeneity	NOUN
admet-2859	97	17	of	of	ADP
admet-2859	97	18	slopes	slope	NOUN
admet-2859	97	19	test	test	NOUN
admet-2859	97	20	p	p	NOUN
admet-2859	97	21	-	-	PUNCT
admet-2859	97	22	value	value	NOUN
admet-2859	97	23	for	for	ADP
admet-2859	97	24	‘	'	PUNCT
admet-2859	97	25	cd	cd	NOUN
admet-2859	97	26	-	-	PUNCT
admet-2859	97	27	none	none	NOUN
admet-2859	97	28	’	'	PUNCT
admet-2859	97	29	and	and	CCONJ
admet-2859	97	30	‘	'	PUNCT
admet-2859	97	31	cdacceptor	cdacceptor	NOUN
admet-2859	97	32	’	'	PUNCT
admet-2859	97	33	p	p	NOUN
admet-2859	97	34	<	<	X
admet-2859	97	35	0.05	0.05	NUM
admet-2859	97	36	)	)	PUNCT
admet-2859	97	37	.	.	PUNCT
admet-2859	98	1	however	however	ADV
admet-2859	98	2	,	,	PUNCT
admet-2859	98	3	for	for	ADP
admet-2859	98	4	both	both	DET
admet-2859	98	5	size	size	NOUN
admet-2859	98	6	-	-	PUNCT
admet-2859	98	7	exclusion	exclusion	NOUN
admet-2859	98	8	membranes	membrane	NOUN
admet-2859	98	9	,	,	PUNCT
admet-2859	98	10	the	the	DET
admet-2859	98	11	sink	sink	NOUN
admet-2859	98	12	effect	effect	NOUN
admet-2859	98	13	is	be	AUX
admet-2859	98	14	negligible	negligible	ADJ
admet-2859	98	15	,	,	PUNCT
admet-2859	98	16	most	most	ADV
admet-2859	98	17	probably	probably	ADV
admet-2859	98	18	due	due	ADJ
admet-2859	98	19	to	to	ADP
admet-2859	98	20	cd	cd	PROPN
admet-2859	98	21	’s	’s	PART
admet-2859	98	22	ability	ability	NOUN
admet-2859	98	23	to	to	PART
admet-2859	98	24	pass	pass	VERB
admet-2859	98	25	through	through	ADP
admet-2859	98	26	the	the	DET
admet-2859	98	27	membrane	membrane	NOUN
admet-2859	98	28	from	from	ADP
admet-2859	98	29	the	the	DET
admet-2859	98	30	acceptor	acceptor	NOUN
admet-2859	98	31	side	side	NOUN
admet-2859	98	32	to	to	ADP
admet-2859	98	33	the	the	DET
admet-2859	98	34	donor	donor	NOUN
admet-2859	98	35	side	side	NOUN
admet-2859	98	36	.	.	PUNCT
admet-2859	99	1	a	a	DET
admet-2859	99	2	similar	similar	ADJ
admet-2859	99	3	situation	situation	NOUN
admet-2859	99	4	arises	arise	VERB
admet-2859	99	5	when	when	SCONJ
admet-2859	99	6	cd	cd	PROPN
admet-2859	99	7	in	in	ADP
admet-2859	99	8	the	the	DET
admet-2859	99	9	donor	donor	NOUN
admet-2859	99	10	compartment	compartment	NOUN
admet-2859	99	11	is	be	AUX
admet-2859	99	12	compared	compare	VERB
admet-2859	99	13	with	with	ADP
admet-2859	99	14	the	the	DET
admet-2859	99	15	scenario	scenario	NOUN
admet-2859	99	16	where	where	SCONJ
admet-2859	99	17	both	both	DET
admet-2859	99	18	chambers	chamber	NOUN
admet-2859	99	19	contain	contain	VERB
admet-2859	99	20	cd	cd	NOUN
admet-2859	99	21	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	PROPN
admet-2859	99	22	p.	p.	PROPN
admet-2859	99	23	tőzsér	tőzsér	PROPN
admet-2859	100	1	et	et	PROPN
admet-2859	100	2	al	al	PROPN
admet-2859	100	3	.	.	PROPN
admet-2859	100	4	admet	admet	PROPN
admet-2859	100	5	&	&	CCONJ
admet-2859	100	6	dmpk	dmpk	PROPN
admet-2859	100	7	13(5	13(5	NUM
admet-2859	100	8	)	)	PUNCT
admet-2859	100	9	(	(	PUNCT
admet-2859	100	10	2025	2025	NUM
admet-2859	100	11	)	)	PUNCT
admet-2859	100	12	2859	2859	NUM
admet-2859	100	13	6	6	NUM
admet-2859	100	14	(	(	PUNCT
admet-2859	100	15	table	table	NOUN
admet-2859	100	16	2	2	NUM
admet-2859	100	17	,	,	PUNCT
admet-2859	100	18	p	p	NOUN
admet-2859	100	19	-	-	PUNCT
admet-2859	100	20	value	value	NOUN
admet-2859	100	21	for	for	ADP
admet-2859	100	22	‘	'	PUNCT
admet-2859	100	23	cd	cd	NOUN
admet-2859	100	24	-	-	PUNCT
admet-2859	100	25	donor	donor	NOUN
admet-2859	100	26	’	'	PUNCT
admet-2859	100	27	and	and	CCONJ
admet-2859	100	28	‘	'	PUNCT
admet-2859	100	29	cd	cd	NOUN
admet-2859	100	30	-	-	PUNCT
admet-2859	100	31	both	both	PRON
admet-2859	100	32	’	'	PUNCT
admet-2859	100	33	):	):	PUNCT
admet-2859	100	34	in	in	ADP
admet-2859	100	35	case	case	NOUN
admet-2859	100	36	of	of	ADP
admet-2859	100	37	the	the	DET
admet-2859	100	38	lipophilic	lipophilic	ADJ
admet-2859	100	39	membrane	membrane	NOUN
admet-2859	100	40	,	,	PUNCT
admet-2859	100	41	the	the	DET
admet-2859	100	42	sink	sink	NOUN
admet-2859	100	43	effect	effect	NOUN
admet-2859	100	44	is	be	AUX
admet-2859	100	45	significant	significant	ADJ
admet-2859	100	46	;	;	PUNCT
admet-2859	100	47	however	however	ADV
admet-2859	100	48	,	,	PUNCT
admet-2859	100	49	it	it	PRON
admet-2859	100	50	is	be	AUX
admet-2859	100	51	negligible	negligible	ADJ
admet-2859	100	52	for	for	ADP
admet-2859	100	53	size	size	NOUN
admet-2859	100	54	-	-	PUNCT
admet-2859	100	55	exclusion	exclusion	NOUN
admet-2859	100	56	membranes	membrane	NOUN
admet-2859	100	57	.	.	PUNCT
admet-2859	101	1	figure	figure	NOUN
admet-2859	101	2	2	2	NUM
admet-2859	101	3	.	.	PUNCT
admet-2859	101	4	examples	example	NOUN
admet-2859	101	5	of	of	ADP
admet-2859	101	6	donor	donor	NOUN
admet-2859	101	7	and	and	CCONJ
admet-2859	101	8	acceptor	acceptor	NOUN
admet-2859	101	9	concentration	concentration	NOUN
admet-2859	101	10	–	–	PUNCT
admet-2859	101	11	time	time	NOUN
admet-2859	101	12	profiles	profile	NOUN
admet-2859	101	13	of	of	ADP
admet-2859	101	14	car	car	NOUN
admet-2859	101	15	in	in	ADP
admet-2859	101	16	ph	ph	ADJ
admet-2859	101	17	10	10	NUM
admet-2859	101	18	prisma	prisma	NOUN
admet-2859	101	19	buffer	buffer	NOUN
admet-2859	101	20	:	:	PUNCT
admet-2859	101	21	a	a	X
admet-2859	101	22	)	)	PUNCT
admet-2859	101	23	hpβ	hpβ	NOUN
admet-2859	101	24	-	-	PUNCT
admet-2859	101	25	cd	cd	NOUN
admet-2859	101	26	present	present	NOUN
admet-2859	101	27	on	on	ADP
admet-2859	101	28	the	the	DET
admet-2859	101	29	acceptor	acceptor	NOUN
admet-2859	101	30	side	side	NOUN
admet-2859	101	31	of	of	ADP
admet-2859	101	32	the	the	DET
admet-2859	101	33	membrane	membrane	NOUN
admet-2859	101	34	b	b	NOUN
admet-2859	101	35	)	)	PUNCT
admet-2859	101	36	hp	hp	PROPN
admet-2859	101	37	-	-	PUNCT
admet-2859	101	38	β	β	NOUN
admet-2859	101	39	-	-	NOUN
admet-2859	101	40	cd	cd	ADJ
admet-2859	101	41	present	present	NOUN
admet-2859	101	42	on	on	ADP
admet-2859	101	43	both	both	DET
admet-2859	101	44	sides	side	NOUN
admet-2859	101	45	of	of	ADP
admet-2859	101	46	the	the	DET
admet-2859	101	47	membrane	membrane	NOUN
admet-2859	101	48	for	for	ADP
admet-2859	101	49	the	the	DET
admet-2859	101	50	lipophilic	lipophilic	ADJ
admet-2859	101	51	membrane	membrane	NOUN
admet-2859	101	52	,	,	PUNCT
admet-2859	101	53	1	1	NUM
admet-2859	101	54	kda	kda	NOUN
admet-2859	101	55	size	size	NOUN
admet-2859	101	56	-	-	PUNCT
admet-2859	101	57	exclusion	exclusion	NOUN
admet-2859	101	58	membrane	membrane	NOUN
admet-2859	101	59	,	,	PUNCT
admet-2859	101	60	and	and	CCONJ
admet-2859	101	61	6	6	NUM
admet-2859	101	62	kda	kda	NOUN
admet-2859	101	63	size	size	NOUN
admet-2859	101	64	-	-	PUNCT
admet-2859	101	65	exclusion	exclusion	NOUN
admet-2859	101	66	membrane	membrane	NOUN
admet-2859	101	67	data	datum	NOUN
admet-2859	101	68	coming	come	VERB
admet-2859	101	69	from	from	ADP
admet-2859	101	70	the	the	DET
admet-2859	101	71	same	same	ADJ
admet-2859	101	72	diffusion	diffusion	NOUN
admet-2859	101	73	cell	cell	NOUN
admet-2859	101	74	assay	assay	NOUN
admet-2859	101	75	is	be	AUX
admet-2859	101	76	marked	mark	VERB
admet-2859	101	77	with	with	ADP
admet-2859	101	78	the	the	DET
admet-2859	101	79	same	same	ADJ
admet-2859	101	80	colours	colour	NOUN
admet-2859	101	81	)	)	PUNCT
admet-2859	101	82	donor	donor	NOUN
admet-2859	101	83	concentration	concentration	NOUN
admet-2859	101	84	,	,	PUNCT
admet-2859	101	85	g	g	VERB
admet-2859	101	86	ml-1	ml-1	PRON
admet-2859	101	87	donor	donor	NOUN
admet-2859	101	88	concentration	concentration	NOUN
admet-2859	101	89	,	,	PUNCT
admet-2859	101	90	g	g	VERB
admet-2859	101	91	ml-1	ml-1	PRON
admet-2859	101	92	donor	donor	NOUN
admet-2859	101	93	concentration	concentration	NOUN
admet-2859	101	94	,	,	PUNCT
admet-2859	101	95	g	g	PROPN
admet-2859	101	96	ml-1	ml-1	PUNCT
admet-2859	101	97	figure	figure	NOUN
admet-2859	101	98	3	3	NUM
admet-2859	101	99	.	.	PUNCT
admet-2859	101	100	flux	flux	NOUN
admet-2859	101	101	–	–	PUNCT
admet-2859	101	102	donor	donor	NOUN
admet-2859	101	103	concentration	concentration	NOUN
admet-2859	101	104	curves	curve	NOUN
admet-2859	101	105	in	in	ADP
admet-2859	101	106	ph	ph	ADJ
admet-2859	101	107	10	10	NUM
admet-2859	101	108	buffer	buffer	NOUN
admet-2859	101	109	with	with	ADP
admet-2859	101	110	250	250	NUM
admet-2859	101	111	rpm	rpm	ADJ
admet-2859	101	112	stirring	stirring	NOUN
admet-2859	101	113	rate	rate	NOUN
admet-2859	101	114	for	for	ADP
admet-2859	101	115	lipophilic	lipophilic	ADJ
admet-2859	101	116	membrane	membrane	NOUN
admet-2859	101	117	,	,	PUNCT
admet-2859	101	118	1	1	NUM
admet-2859	101	119	and	and	CCONJ
admet-2859	101	120	6	6	NUM
admet-2859	101	121	kda	kda	NOUN
admet-2859	101	122	size	size	NOUN
admet-2859	101	123	-	-	PUNCT
admet-2859	101	124	exclusion	exclusion	NOUN
admet-2859	101	125	membranes	membrane	NOUN
admet-2859	101	126	.	.	PUNCT
admet-2859	102	1	no	no	DET
admet-2859	102	2	hp	hp	PROPN
admet-2859	102	3	-	-	PUNCT
admet-2859	102	4	β	β	NOUN
admet-2859	102	5	-	-	NOUN
admet-2859	102	6	cd	cd	NOUN
admet-2859	102	7	present	present	NOUN
admet-2859	102	8	on	on	ADP
admet-2859	102	9	either	either	DET
admet-2859	102	10	side	side	NOUN
admet-2859	102	11	of	of	ADP
admet-2859	102	12	the	the	DET
admet-2859	102	13	membrane	membrane	NOUN
admet-2859	102	14	with	with	ADP
admet-2859	102	15	red	red	ADJ
admet-2859	102	16	dotted	dot	VERB
admet-2859	102	17	line	line	NOUN
admet-2859	102	18	called	call	VERB
admet-2859	102	19	‘	'	PUNCT
admet-2859	102	20	cd	cd	NOUN
admet-2859	102	21	-	-	PUNCT
admet-2859	102	22	none	none	NOUN
admet-2859	102	23	’	'	PUNCT
admet-2859	102	24	,	,	PUNCT
admet-2859	102	25	addition	addition	NOUN
admet-2859	102	26	of	of	ADP
admet-2859	102	27	hp	hp	NOUN
admet-2859	102	28	-	-	PUNCT
admet-2859	102	29	β	β	NOUN
admet-2859	102	30	-	-	NOUN
admet-2859	102	31	cd	cd	NOUN
admet-2859	102	32	to	to	PART
admet-2859	102	33	acceptor	acceptor	NOUN
admet-2859	102	34	side	side	NOUN
admet-2859	102	35	with	with	ADP
admet-2859	102	36	purple	purple	ADJ
admet-2859	102	37	dots	dot	NOUN
admet-2859	102	38	called	call	VERB
admet-2859	102	39	‘	'	PUNCT
admet-2859	102	40	cd	cd	NOUN
admet-2859	102	41	-	-	PUNCT
admet-2859	102	42	acceptor	acceptor	NOUN
admet-2859	102	43	’	'	PUNCT
admet-2859	102	44	,	,	PUNCT
admet-2859	102	45	addition	addition	NOUN
admet-2859	102	46	of	of	ADP
admet-2859	102	47	hp	hp	NOUN
admet-2859	102	48	-	-	PUNCT
admet-2859	102	49	β	β	NOUN
admet-2859	102	50	-	-	NOUN
admet-2859	102	51	cd	cd	NOUN
admet-2859	102	52	to	to	PART
admet-2859	102	53	donor	donor	VERB
admet-2859	102	54	side	side	NOUN
admet-2859	102	55	with	with	ADP
admet-2859	102	56	green	green	PROPN
admet-2859	102	57	dashed	dash	VERB
admet-2859	102	58	line	line	NOUN
admet-2859	102	59	called	call	VERB
admet-2859	102	60	‘	'	PUNCT
admet-2859	102	61	cd	cd	NOUN
admet-2859	102	62	-	-	PUNCT
admet-2859	102	63	donor	donor	NOUN
admet-2859	102	64	’	'	PUNCT
admet-2859	102	65	and	and	CCONJ
admet-2859	102	66	addition	addition	NOUN
admet-2859	102	67	of	of	ADP
admet-2859	102	68	hp	hp	NOUN
admet-2859	102	69	-	-	PUNCT
admet-2859	102	70	β	β	NOUN
admet-2859	102	71	-	-	NOUN
admet-2859	102	72	cd	cd	NOUN
admet-2859	102	73	to	to	ADP
admet-2859	102	74	both	both	DET
admet-2859	102	75	sides	side	NOUN
admet-2859	102	76	with	with	ADP
admet-2859	102	77	blue	blue	ADJ
admet-2859	102	78	triangles	triangle	NOUN
admet-2859	102	79	called	call	VERB
admet-2859	102	80	‘	'	PUNCT
admet-2859	102	81	cd	cd	NOUN
admet-2859	102	82	-	-	PUNCT
admet-2859	102	83	both	both	PRON
admet-2859	102	84	’	'	PUNCT
admet-2859	102	85	notably	notably	ADV
admet-2859	102	86	,	,	PUNCT
admet-2859	102	87	despite	despite	SCONJ
admet-2859	102	88	the	the	DET
admet-2859	102	89	same	same	ADJ
admet-2859	102	90	amount	amount	NOUN
admet-2859	102	91	of	of	ADP
admet-2859	102	92	cd	cd	PROPN
admet-2859	102	93	applied	apply	VERB
admet-2859	102	94	to	to	ADP
admet-2859	102	95	both	both	DET
admet-2859	102	96	the	the	DET
admet-2859	102	97	donor	donor	NOUN
admet-2859	102	98	and	and	CCONJ
admet-2859	102	99	acceptor	acceptor	NOUN
admet-2859	102	100	side	side	NOUN
admet-2859	102	101	,	,	PUNCT
admet-2859	102	102	the	the	DET
admet-2859	102	103	cd	cd	PROPN
admet-2859	102	104	on	on	ADP
admet-2859	102	105	the	the	DET
admet-2859	102	106	donor	donor	NOUN
admet-2859	102	107	side	side	NOUN
admet-2859	102	108	exerts	exert	VERB
admet-2859	102	109	a	a	DET
admet-2859	102	110	significantly	significantly	ADV
admet-2859	102	111	greater	great	ADJ
admet-2859	102	112	negative	negative	ADJ
admet-2859	102	113	effect	effect	NOUN
admet-2859	102	114	on	on	ADP
admet-2859	102	115	flux	flux	NOUN
admet-2859	102	116	and	and	CCONJ
admet-2859	102	117	therefore	therefore	ADV
admet-2859	102	118	permeability	permeability	NOUN
admet-2859	102	119	(	(	PUNCT
admet-2859	102	120	figures	figure	NOUN
admet-2859	102	121	3	3	NUM
admet-2859	102	122	and	and	CCONJ
admet-2859	102	123	4	4	NUM
admet-2859	102	124	)	)	PUNCT
admet-2859	102	125	than	than	ADP
admet-2859	102	126	the	the	DET
admet-2859	102	127	positive	positive	ADJ
admet-2859	102	128	effect	effect	NOUN
admet-2859	102	129	of	of	ADP
admet-2859	102	130	cd	cd	PROPN
admet-2859	102	131	used	use	VERB
admet-2859	102	132	to	to	PART
admet-2859	102	133	create	create	VERB
admet-2859	102	134	sink	sink	NOUN
admet-2859	102	135	conditions	condition	NOUN
admet-2859	102	136	in	in	ADP
admet-2859	102	137	all	all	DET
admet-2859	102	138	3	3	NUM
admet-2859	102	139	membrane	membrane	NOUN
admet-2859	102	140	types	type	NOUN
admet-2859	102	141	.	.	PUNCT
admet-2859	103	1	therefore	therefore	ADV
admet-2859	103	2	,	,	PUNCT
admet-2859	103	3	in	in	ADP
admet-2859	103	4	the	the	DET
admet-2859	103	5	scenario	scenario	NOUN
admet-2859	103	6	f	f	PROPN
admet-2859	103	7	lu	lu	PROPN
admet-2859	103	8	x	x	NOUN
admet-2859	103	9	,	,	PUNCT
admet-2859	103	10			NOUN
admet-2859	103	11	g	g	NOUN
admet-2859	103	12	m	m	NOUN
admet-2859	103	13	in	in	ADP
admet-2859	103	14	-1	-1	PROPN
admet-2859	103	15	c	c	NOUN
admet-2859	103	16	m	m	VERB
admet-2859	103	17	-2	-2	INTJ
admet-2859	103	18	f	f	X
admet-2859	103	19	lu	lu	PROPN
admet-2859	103	20	x	x	NOUN
admet-2859	103	21	,	,	PUNCT
admet-2859	103	22			NOUN
admet-2859	103	23	g	g	NOUN
admet-2859	103	24	m	m	NOUN
admet-2859	103	25	in	in	ADP
admet-2859	103	26	-1	-1	PROPN
admet-2859	103	27	c	c	NOUN
admet-2859	103	28	m	m	VERB
admet-2859	103	29	-2	-2	INTJ
admet-2859	103	30	f	f	X
admet-2859	103	31	lu	lu	PROPN
admet-2859	103	32	x	x	NOUN
admet-2859	103	33	,	,	PUNCT
admet-2859	103	34			NOUN
admet-2859	103	35	g	g	NOUN
admet-2859	103	36	m	m	NOUN
admet-2859	103	37	in	in	ADP
admet-2859	103	38	-1	-1	PROPN
admet-2859	103	39	c	c	NOUN
admet-2859	103	40	m	m	VERB
admet-2859	103	41	-2	-2	NOUN
admet-2859	103	42	admet	admet	PROPN
admet-2859	103	43	&	&	CCONJ
admet-2859	103	44	dmpk	dmpk	PROPN
admet-2859	103	45	13(5	13(5	NUM
admet-2859	103	46	)	)	PUNCT
admet-2859	103	47	(	(	PUNCT
admet-2859	103	48	2025	2025	NUM
admet-2859	103	49	)	)	PUNCT
admet-2859	103	50	2859	2859	NUM
admet-2859	103	51	comparison	comparison	NOUN
admet-2859	103	52	of	of	ADP
admet-2859	103	53	lipophilic	lipophilic	ADJ
admet-2859	103	54	and	and	CCONJ
admet-2859	103	55	size	size	NOUN
admet-2859	103	56	-	-	PUNCT
admet-2859	103	57	exclusion	exclusion	NOUN
admet-2859	103	58	membranes	membrane	NOUN
admet-2859	103	59	doi	doi	NOUN
admet-2859	103	60	:	:	PUNCT
admet-2859	103	61	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	X
admet-2859	103	62	7	7	NUM
admet-2859	103	63	where	where	SCONJ
admet-2859	103	64	both	both	DET
admet-2859	103	65	sides	side	NOUN
admet-2859	103	66	contain	contain	VERB
admet-2859	103	67	cd	cd	PROPN
admet-2859	103	68	,	,	PUNCT
admet-2859	103	69	the	the	DET
admet-2859	103	70	transport	transport	NOUN
admet-2859	103	71	of	of	ADP
admet-2859	103	72	the	the	DET
admet-2859	103	73	api	api	NOUN
admet-2859	103	74	is	be	AUX
admet-2859	103	75	much	much	ADV
admet-2859	103	76	slower	slow	ADJ
admet-2859	103	77	than	than	ADP
admet-2859	103	78	in	in	ADP
admet-2859	103	79	the	the	DET
admet-2859	103	80	case	case	NOUN
admet-2859	103	81	where	where	SCONJ
admet-2859	103	82	no	no	DET
admet-2859	103	83	cd	cd	NOUN
admet-2859	103	84	is	be	AUX
admet-2859	103	85	added	add	VERB
admet-2859	103	86	to	to	ADP
admet-2859	103	87	either	either	DET
admet-2859	103	88	side	side	NOUN
admet-2859	103	89	of	of	ADP
admet-2859	103	90	the	the	DET
admet-2859	103	91	membrane	membrane	NOUN
admet-2859	103	92	(	(	PUNCT
admet-2859	103	93	see	see	VERB
admet-2859	103	94	figures	figure	NOUN
admet-2859	103	95	3	3	NUM
admet-2859	103	96	and	and	CCONJ
admet-2859	103	97	4	4	NUM
admet-2859	103	98	,	,	PUNCT
admet-2859	103	99	cd	cd	NOUN
admet-2859	103	100	-	-	PUNCT
admet-2859	103	101	none	none	NOUN
admet-2859	103	102	case	case	NOUN
admet-2859	103	103	)	)	PUNCT
admet-2859	103	104	,	,	PUNCT
admet-2859	103	105	regardless	regardless	ADV
admet-2859	103	106	of	of	ADP
admet-2859	103	107	the	the	DET
admet-2859	103	108	type	type	NOUN
admet-2859	103	109	of	of	ADP
admet-2859	103	110	membrane	membrane	NOUN
admet-2859	103	111	.	.	PUNCT
admet-2859	104	1	for	for	ADP
admet-2859	104	2	a	a	DET
admet-2859	104	3	detailed	detailed	ADJ
admet-2859	104	4	description	description	NOUN
admet-2859	104	5	of	of	ADP
admet-2859	104	6	the	the	DET
admet-2859	104	7	effect	effect	NOUN
admet-2859	104	8	of	of	ADP
admet-2859	104	9	cd	cd	PROPN
admet-2859	104	10	used	use	VERB
admet-2859	104	11	in	in	ADP
admet-2859	104	12	the	the	DET
admet-2859	104	13	donor	donor	NOUN
admet-2859	104	14	compartment	compartment	NOUN
admet-2859	104	15	,	,	PUNCT
admet-2859	104	16	see	see	VERB
admet-2859	104	17	the	the	DET
admet-2859	104	18	previous	previous	ADJ
admet-2859	104	19	publication	publication	NOUN
admet-2859	105	1	[	[	X
admet-2859	105	2	1	1	NUM
admet-2859	105	3	]	]	PUNCT
admet-2859	105	4	.	.	PUNCT
admet-2859	106	1	table	table	NOUN
admet-2859	106	2	2	2	NUM
admet-2859	106	3	.	.	X
admet-2859	106	4	homogeneity	homogeneity	NOUN
admet-2859	106	5	of	of	ADP
admet-2859	106	6	slopes	slope	NOUN
admet-2859	106	7	test	test	NOUN
admet-2859	106	8	results	result	NOUN
admet-2859	106	9	for	for	ADP
admet-2859	106	10	flux	flux	NOUN
admet-2859	106	11	-	-	PUNCT
admet-2859	106	12	donor	donor	NOUN
admet-2859	106	13	concentration	concentration	NOUN
admet-2859	106	14	curves	curve	NOUN
admet-2859	106	15	in	in	ADP
admet-2859	106	16	ph	ph	ADJ
admet-2859	106	17	10	10	NUM
admet-2859	106	18	buffer	buffer	NOUN
admet-2859	106	19	with	with	ADP
admet-2859	106	20	250	250	NUM
admet-2859	106	21	rpm	rpm	ADJ
admet-2859	106	22	stirring	stirring	NOUN
admet-2859	106	23	rate	rate	NOUN
admet-2859	106	24	for	for	ADP
admet-2859	106	25	lipophilic	lipophilic	ADJ
admet-2859	106	26	membrane	membrane	NOUN
admet-2859	106	27	,	,	PUNCT
admet-2859	106	28	1	1	NUM
admet-2859	106	29	and	and	CCONJ
admet-2859	106	30	6	6	NUM
admet-2859	106	31	kda	kda	NOUN
admet-2859	106	32	size	size	NOUN
admet-2859	106	33	-	-	PUNCT
admet-2859	106	34	exclusion	exclusion	NOUN
admet-2859	106	35	membranes	membrane	NOUN
admet-2859	106	36	,	,	PUNCT
admet-2859	106	37	significance	significance	NOUN
admet-2859	106	38	:	:	PUNCT
admet-2859	106	39	p	p	X
admet-2859	106	40	<	<	X
admet-2859	106	41	0.05	0.05	NUM
admet-2859	106	42	is	be	AUX
admet-2859	106	43	highlighted	highlight	VERB
admet-2859	106	44	in	in	ADP
admet-2859	106	45	red	red	ADJ
admet-2859	106	46	p	p	NOUN
admet-2859	106	47	-	-	PUNCT
admet-2859	106	48	value	value	NOUN
admet-2859	106	49	for	for	ADP
admet-2859	106	50	cd	cd	NOUN
admet-2859	106	51	-	-	PUNCT
admet-2859	106	52	none	none	NOUN
admet-2859	106	53	and	and	CCONJ
admet-2859	106	54	cd	cd	NOUN
admet-2859	106	55	-	-	PUNCT
admet-2859	106	56	acceptor	acceptor	NOUN
admet-2859	106	57	p	p	NOUN
admet-2859	106	58	-	-	PUNCT
admet-2859	106	59	value	value	NOUN
admet-2859	106	60	for	for	ADP
admet-2859	106	61	cd	cd	NOUN
admet-2859	106	62	-	-	PUNCT
admet-2859	106	63	donor	donor	NOUN
admet-2859	106	64	and	and	CCONJ
admet-2859	106	65	cd	cd	PROPN
admet-2859	106	66	-	-	PUNCT
admet-2859	106	67	both	both	CCONJ
admet-2859	106	68	lipophilic	lipophilic	ADJ
admet-2859	106	69	0.001748	0.001748	NUM
admet-2859	106	70	0.000562	0.000562	NUM
admet-2859	106	71	1	1	NUM
admet-2859	106	72	kda	kda	NOUN
admet-2859	106	73	0.689878	0.689878	NUM
admet-2859	106	74	0.594536	0.594536	NUM
admet-2859	106	75	6	6	NUM
admet-2859	106	76	kda	kda	NOUN
admet-2859	106	77	0.176109	0.176109	NUM
admet-2859	106	78	0.127748	0.127748	NUM
admet-2859	106	79	figure	figure	NOUN
admet-2859	106	80	4	4	NUM
admet-2859	106	81	.	.	PUNCT
admet-2859	106	82	apparent	apparent	ADJ
admet-2859	106	83	permeability	permeability	NOUN
admet-2859	106	84	values	value	NOUN
admet-2859	106	85	in	in	ADP
admet-2859	106	86	a	a	DET
admet-2859	106	87	ph	ph	ADJ
admet-2859	106	88	10	10	NUM
admet-2859	106	89	buffer	buffer	NOUN
admet-2859	106	90	with	with	ADP
admet-2859	106	91	a	a	DET
admet-2859	106	92	250	250	NUM
admet-2859	106	93	rpm	rpm	ADJ
admet-2859	106	94	stirring	stirring	NOUN
admet-2859	106	95	rate	rate	NOUN
admet-2859	106	96	in	in	ADP
admet-2859	106	97	the	the	DET
admet-2859	106	98	case	case	NOUN
admet-2859	106	99	of	of	ADP
admet-2859	106	100	lipophilic	lipophilic	ADJ
admet-2859	106	101	membrane	membrane	NOUN
admet-2859	106	102	,	,	PUNCT
admet-2859	106	103	1	1	NUM
admet-2859	106	104	and	and	CCONJ
admet-2859	106	105	6	6	NUM
admet-2859	106	106	kda	kda	NOUN
admet-2859	106	107	size	size	NOUN
admet-2859	106	108	-	-	PUNCT
admet-2859	106	109	exclusion	exclusion	NOUN
admet-2859	106	110	membranes	membrane	NOUN
admet-2859	106	111	.	.	PUNCT
admet-2859	107	1	no	no	DET
admet-2859	107	2	hp	hp	PROPN
admet-2859	107	3	-	-	PUNCT
admet-2859	107	4	β	β	NOUN
admet-2859	107	5	-	-	NOUN
admet-2859	107	6	cd	cd	NOUN
admet-2859	107	7	present	present	NOUN
admet-2859	107	8	on	on	ADP
admet-2859	107	9	either	either	DET
admet-2859	107	10	side	side	NOUN
admet-2859	107	11	of	of	ADP
admet-2859	107	12	the	the	DET
admet-2859	107	13	membrane	membrane	NOUN
admet-2859	107	14	with	with	ADP
admet-2859	107	15	red	red	ADJ
admet-2859	107	16	,	,	PUNCT
admet-2859	107	17	addition	addition	NOUN
admet-2859	107	18	of	of	ADP
admet-2859	107	19	hp	hp	NOUN
admet-2859	107	20	-	-	PUNCT
admet-2859	107	21	β	β	NOUN
admet-2859	107	22	-	-	NOUN
admet-2859	107	23	cd	cd	NOUN
admet-2859	107	24	to	to	PART
admet-2859	107	25	acceptor	acceptor	NOUN
admet-2859	107	26	side	side	NOUN
admet-2859	107	27	with	with	ADP
admet-2859	107	28	purple	purple	ADJ
admet-2859	107	29	,	,	PUNCT
admet-2859	107	30	addition	addition	NOUN
admet-2859	107	31	of	of	ADP
admet-2859	107	32	hp	hp	NOUN
admet-2859	107	33	-	-	PUNCT
admet-2859	107	34	β	β	NOUN
admet-2859	107	35	-	-	NOUN
admet-2859	107	36	cd	cd	NOUN
admet-2859	107	37	to	to	PART
admet-2859	107	38	donor	donor	VERB
admet-2859	107	39	side	side	NOUN
admet-2859	107	40	with	with	ADP
admet-2859	107	41	green	green	ADJ
admet-2859	107	42	and	and	CCONJ
admet-2859	107	43	addition	addition	NOUN
admet-2859	107	44	of	of	ADP
admet-2859	107	45	hp	hp	NOUN
admet-2859	107	46	-	-	PUNCT
admet-2859	107	47	β	β	NOUN
admet-2859	107	48	-	-	NOUN
admet-2859	107	49	cd	cd	NOUN
admet-2859	107	50	to	to	ADP
admet-2859	107	51	both	both	DET
admet-2859	107	52	sides	side	NOUN
admet-2859	107	53	with	with	ADP
admet-2859	107	54	blue	blue	ADJ
admet-2859	107	55	from	from	ADP
admet-2859	107	56	the	the	DET
admet-2859	107	57	apparent	apparent	ADJ
admet-2859	107	58	permeability	permeability	NOUN
admet-2859	107	59	values	value	NOUN
admet-2859	107	60	depicted	depict	VERB
admet-2859	107	61	in	in	ADP
admet-2859	107	62	figure	figure	NOUN
admet-2859	107	63	4	4	NUM
admet-2859	107	64	and	and	CCONJ
admet-2859	107	65	the	the	DET
admet-2859	107	66	results	result	NOUN
admet-2859	107	67	of	of	ADP
admet-2859	107	68	ph	ph	ADJ
admet-2859	107	69	-	-	PUNCT
admet-2859	107	70	permeability	permeability	NOUN
admet-2859	107	71	profiling	profiling	NOUN
admet-2859	107	72	in	in	ADP
admet-2859	107	73	previous	previous	ADJ
admet-2859	107	74	publication	publication	NOUN
admet-2859	107	75	[	[	X
admet-2859	107	76	1	1	NUM
admet-2859	107	77	]	]	PUNCT
admet-2859	107	78	,	,	PUNCT
admet-2859	107	79	the	the	DET
admet-2859	107	80	puwl	puwl	NOUN
admet-2859	107	81	,	,	PUNCT
admet-2859	107	82	pm	pm	NOUN
admet-2859	107	83	values	value	NOUN
admet-2859	107	84	were	be	AUX
admet-2859	107	85	calculated	calculate	VERB
admet-2859	107	86	(	(	PUNCT
admet-2859	107	87	table	table	NOUN
admet-2859	107	88	3	3	NUM
admet-2859	107	89	)	)	PUNCT
admet-2859	107	90	assuming	assume	VERB
admet-2859	107	91	that	that	SCONJ
admet-2859	107	92	:	:	PUNCT
admet-2859	107	93	a	a	X
admet-2859	107	94	)	)	PUNCT
admet-2859	107	95	the	the	DET
admet-2859	107	96	uwl	uwl	NOUN
admet-2859	107	97	exist	exist	VERB
admet-2859	107	98	symmetrically	symmetrically	ADV
admet-2859	107	99	on	on	ADP
admet-2859	107	100	both	both	DET
admet-2859	107	101	sides	side	NOUN
admet-2859	107	102	of	of	ADP
admet-2859	107	103	the	the	DET
admet-2859	107	104	membrane	membrane	NOUN
admet-2859	107	105	,	,	PUNCT
admet-2859	107	106	b	b	X
admet-2859	107	107	)	)	PUNCT
admet-2859	107	108	the	the	DET
admet-2859	107	109	thickness	thickness	NOUN
admet-2859	107	110	of	of	ADP
admet-2859	107	111	the	the	DET
admet-2859	107	112	uwl	uwl	NOUN
admet-2859	107	113	is	be	AUX
admet-2859	107	114	the	the	DET
admet-2859	107	115	same	same	ADJ
admet-2859	107	116	for	for	ADP
admet-2859	107	117	different	different	ADJ
admet-2859	107	118	membranes	membrane	NOUN
admet-2859	107	119	when	when	SCONJ
admet-2859	107	120	using	use	VERB
admet-2859	107	121	the	the	DET
admet-2859	107	122	same	same	ADJ
admet-2859	107	123	side	side	NOUN
admet-2859	107	124	-	-	PUNCT
admet-2859	107	125	by	by	ADP
admet-2859	107	126	-	-	PUNCT
admet-2859	107	127	side	side	NOUN
admet-2859	107	128	diffusion	diffusion	NOUN
admet-2859	107	129	cell	cell	NOUN
admet-2859	107	130	with	with	ADP
admet-2859	107	131	the	the	DET
admet-2859	107	132	same	same	ADJ
admet-2859	107	133	experimental	experimental	ADJ
admet-2859	107	134	conditions	condition	NOUN
admet-2859	107	135	(	(	PUNCT
admet-2859	107	136	ph	ph	NOUN
admet-2859	107	137	of	of	ADP
admet-2859	107	138	media	medium	NOUN
admet-2859	107	139	,	,	PUNCT
admet-2859	107	140	hp	hp	PROPN
admet-2859	107	141	-	-	PUNCT
admet-2859	107	142	β	β	NOUN
admet-2859	107	143	-	-	NOUN
admet-2859	107	144	cd	cd	NOUN
admet-2859	107	145	in	in	ADP
admet-2859	107	146	media	medium	NOUN
admet-2859	107	147	,	,	PUNCT
admet-2859	107	148	stirring	stir	VERB
admet-2859	107	149	speed	speed	NOUN
admet-2859	107	150	)	)	PUNCT
admet-2859	107	151	.	.	PUNCT
admet-2859	108	1	table	table	NOUN
admet-2859	108	2	3	3	NUM
admet-2859	108	3	.	.	PUNCT
admet-2859	108	4	summary	summary	NOUN
admet-2859	108	5	table	table	NOUN
admet-2859	108	6	of	of	ADP
admet-2859	108	7	papp	papp	NOUN
admet-2859	108	8	,	,	PUNCT
admet-2859	108	9	puwl	puwl	NOUN
admet-2859	108	10	,	,	PUNCT
admet-2859	108	11	pm	pm	VERB
admet-2859	108	12	values	value	NOUN
admet-2859	108	13	from	from	ADP
admet-2859	108	14	the	the	DET
admet-2859	108	15	in	in	ADV
admet-2859	108	16	vitro	vitro	X
admet-2859	108	17	side	side	NOUN
admet-2859	108	18	-	-	PUNCT
admet-2859	108	19	by	by	ADP
admet-2859	108	20	-	-	PUNCT
admet-2859	108	21	side	side	NOUN
admet-2859	108	22	diffusion	diffusion	NOUN
admet-2859	108	23	cell	cell	NOUN
admet-2859	108	24	assay	assay	VERB
admet-2859	108	25	,	,	PUNCT
admet-2859	108	26	250	250	NUM
admet-2859	108	27	rpm	rpm	ADJ
admet-2859	108	28	lipophilic	lipophilic	ADJ
admet-2859	108	29	membrane	membrane	NOUN
admet-2859	108	30	1	1	NUM
admet-2859	108	31	kda	kda	NOUN
admet-2859	108	32	size	size	NOUN
admet-2859	108	33	-	-	PUNCT
admet-2859	108	34	exclusion	exclusion	NOUN
admet-2859	108	35	membrane	membrane	NOUN
admet-2859	108	36	6	6	NUM
admet-2859	108	37	kda	kda	NOUN
admet-2859	108	38	size	size	NOUN
admet-2859	108	39	-	-	PUNCT
admet-2859	108	40	exclusion	exclusion	NOUN
admet-2859	108	41	membrane	membrane	NOUN
admet-2859	108	42	cdnone	cdnone	NOUN
admet-2859	108	43	cddonor	cddonor	PROPN
admet-2859	108	44	cdacceptor	cdacceptor	NOUN
admet-2859	108	45	cdboth	cdboth	PROPN
admet-2859	108	46	cd	cd	VERB
admet-2859	108	47	none	none	NOUN
admet-2859	108	48	cddonor	cddonor	PROPN
admet-2859	108	49	cdacceptor	cdacceptor	NOUN
admet-2859	109	1	cdboth	cdboth	PROPN
admet-2859	109	2	cd	cd	VERB
admet-2859	109	3	none	none	NOUN
admet-2859	109	4	cddonor	cddonor	PROPN
admet-2859	109	5	cdacceptor	cdacceptor	PROPN
admet-2859	109	6	cd	cd	PROPN
admet-2859	109	7	both	both	CCONJ
admet-2859	109	8	papp	papp	PROPN
admet-2859	109	9	/	/	SYM
admet-2859	109	10	10	10	NUM
admet-2859	109	11	-	-	SYM
admet-2859	109	12	5	5	NUM
admet-2859	109	13	cm	cm	NOUN
admet-2859	109	14	s-1	s-1	NOUN
admet-2859	109	15	10.99	10.99	NUM
admet-2859	109	16	3.66	3.66	NUM
admet-2859	109	17	14.02	14.02	NUM
admet-2859	109	18	5.00	5.00	NUM
admet-2859	109	19	4.94	4.94	NUM
admet-2859	109	20	2.09	2.09	NUM
admet-2859	109	21	5.83	5.83	NUM
admet-2859	109	22	2.68	2.68	NUM
admet-2859	109	23	5.26	5.26	NUM
admet-2859	109	24	2.54	2.54	NUM
admet-2859	109	25	6.60	6.60	NUM
admet-2859	109	26	2.15	2.15	NUM
admet-2859	109	27	pe	pe	PROPN
admet-2859	109	28	/	/	SYM
admet-2859	109	29	10	10	NUM
admet-2859	109	30	-	-	SYM
admet-2859	109	31	5	5	NUM
admet-2859	109	32	cm	cm	NOUN
admet-2859	109	33	s-1	s-1	NOUN
admet-2859	109	34	n.a	n.a	PROPN
admet-2859	109	35	.	.	PROPN
admet-2859	110	1	7.03	7.03	NUM
admet-2859	110	2	14.54	14.54	NUM
admet-2859	110	3	8.33	8.33	NUM
admet-2859	110	4	n.a	n.a	PROPN
admet-2859	110	5	.	.	PROPN
admet-2859	111	1	n.a	n.a	PROPN
admet-2859	111	2	.	.	PROPN
admet-2859	112	1	n.a	n.a	PROPN
admet-2859	112	2	.	.	PROPN
admet-2859	113	1	n.a	n.a	PROPN
admet-2859	113	2	.	.	PROPN
admet-2859	114	1	n.a	n.a	PROPN
admet-2859	114	2	.	.	PROPN
admet-2859	115	1	n.a	n.a	PROPN
admet-2859	115	2	.	.	PROPN
admet-2859	116	1	n.a	n.a	PROPN
admet-2859	116	2	.	.	PROPN
admet-2859	116	3	n.a	n.a	PROPN
admet-2859	116	4	.	.	PROPN
admet-2859	116	5	pm	pm	PROPN
admet-2859	116	6	/	/	SYM
admet-2859	116	7	10	10	NUM
admet-2859	116	8	-	-	SYM
admet-2859	116	9	5	5	NUM
admet-2859	116	10	cm	cm	NOUN
admet-2859	116	11	s-1	s-1	NOUN
admet-2859	116	12	28.73	28.73	NUM
admet-2859	116	13	9.23	9.23	NUM
admet-2859	116	14	*	*	PUNCT
admet-2859	117	1	28.73	28.73	NUM
admet-2859	117	2	*	*	SYM
admet-2859	117	3	9.23	9.23	NUM
admet-2859	117	4	*	*	PUNCT
admet-2859	117	5	6.84	6.84	NUM
admet-2859	117	6	*	*	NUM
admet-2859	117	7	2.25	2.25	NUM
admet-2859	117	8	*	*	PUNCT
admet-2859	117	9	7.27	7.27	NUM
admet-2859	117	10	*	*	NUM
admet-2859	117	11	2.77	2.77	NUM
admet-2859	117	12	*	*	NUM
admet-2859	117	13	7.47	7.47	NUM
admet-2859	117	14	*	*	PUNCT
admet-2859	117	15	2.78	2.78	NUM
admet-2859	117	16	*	*	SYM
admet-2859	117	17	8.51	8.51	NUM
admet-2859	117	18	*	*	SYM
admet-2859	117	19	2.21	2.21	NUM
admet-2859	117	20	*	*	NOUN
admet-2859	117	21	puwl	puwl	NOUN
admet-2859	117	22	/	/	SYM
admet-2859	117	23	10	10	NUM
admet-2859	117	24	-	-	SYM
admet-2859	117	25	5	5	NUM
admet-2859	117	26	cm	cm	NOUN
admet-2859	117	27	s-1	s-1	NOUN
admet-2859	117	28	17.80	17.80	NUM
admet-2859	117	29	*	*	SYM
admet-2859	117	30	29.44	29.44	NUM
admet-2859	117	31	29.44	29.44	NUM
admet-2859	117	32	*	*	NUM
admet-2859	117	33	85.14	85.14	NUM
admet-2859	117	34	17.80	17.80	NUM
admet-2859	117	35	29.44	29.44	NUM
admet-2859	117	36	29.44	29.44	NUM
admet-2859	117	37	85.14	85.14	NUM
admet-2859	117	38	17.80	17.80	NUM
admet-2859	117	39	29.44	29.44	NUM
admet-2859	117	40	29.44	29.44	NUM
admet-2859	117	41	85.14	85.14	NUM
admet-2859	117	42	puwl	puwl	ADJ
admet-2859	117	43	donor	donor	NOUN
admet-2859	117	44	/	/	SYM
admet-2859	117	45	10	10	NUM
admet-2859	117	46	-	-	SYM
admet-2859	117	47	5	5	NUM
admet-2859	117	48	cm	cm	NOUN
admet-2859	117	49	s-1	s-1	NOUN
admet-2859	117	50	35.60	35.60	NUM
admet-2859	117	51	170.29	170.29	NUM
admet-2859	117	52	35.60	35.60	NUM
admet-2859	117	53	170.29	170.29	NUM
admet-2859	117	54	35.60	35.60	NUM
admet-2859	117	55	170.29	170.29	NUM
admet-2859	117	56	35.60	35.60	NUM
admet-2859	117	57	170.29	170.29	NUM
admet-2859	117	58	35.60	35.60	NUM
admet-2859	117	59	170.29	170.29	NUM
admet-2859	117	60	35.60	35.60	NUM
admet-2859	117	61	170.29	170.29	NUM
admet-2859	117	62	puwl	puwl	NOUN
admet-2859	117	63	acceptor	acceptor	NOUN
admet-2859	117	64	/	/	SYM
admet-2859	117	65	10	10	NUM
admet-2859	117	66	-	-	SYM
admet-2859	117	67	5	5	NUM
admet-2859	117	68	cm	cm	NOUN
admet-2859	117	69	s-1	s-1	NOUN
admet-2859	117	70	35.60	35.60	NUM
admet-2859	117	71	35.60	35.60	NUM
admet-2859	117	72	170.29	170.29	NUM
admet-2859	117	73	170.29	170.29	NUM
admet-2859	117	74	35.60	35.60	NUM
admet-2859	117	75	35.60	35.60	NUM
admet-2859	117	76	170.29	170.29	NUM
admet-2859	117	77	170.29	170.29	NUM
admet-2859	117	78	35.60	35.60	NUM
admet-2859	117	79	35.60	35.60	NUM
admet-2859	117	80	170.29	170.29	NUM
admet-2859	117	81	170.29	170.29	NUM
admet-2859	117	82	duwl	duwl	NOUN
admet-2859	117	83	donor	donor	NOUN
admet-2859	117	84	/	/	SYM
admet-2859	117	85	10	10	NUM
admet-2859	117	86	-	-	SYM
admet-2859	117	87	5	5	NUM
admet-2859	117	88	cm	cm	NOUN
admet-2859	117	89	s-1	s-1	NOUN
admet-2859	117	90	0.65	0.65	NUM
admet-2859	117	91	0.44	0.44	NUM
admet-2859	117	92	0.65	0.65	NUM
admet-2859	117	93	0.44	0.44	NUM
admet-2859	117	94	0.65	0.65	NUM
admet-2859	117	95	0.44	0.44	NUM
admet-2859	117	96	0.65	0.65	NUM
admet-2859	117	97	0.44	0.44	NUM
admet-2859	117	98	0.65	0.65	NUM
admet-2859	117	99	0.44	0.44	NUM
admet-2859	117	100	0.65	0.65	NUM
admet-2859	117	101	0.44	0.44	NUM
admet-2859	117	102	duwl	duwl	NOUN
admet-2859	117	103	acceptor	acceptor	NOUN
admet-2859	117	104	/	/	SYM
admet-2859	117	105	10	10	NUM
admet-2859	117	106	-	-	SYM
admet-2859	117	107	5	5	NUM
admet-2859	117	108	cm	cm	NOUN
admet-2859	117	109	s-1	s-1	NOUN
admet-2859	117	110	0.65	0.65	NUM
admet-2859	117	111	0.65	0.65	NUM
admet-2859	117	112	0.44	0.44	NUM
admet-2859	117	113	0.44	0.44	NUM
admet-2859	117	114	0.65	0.65	NUM
admet-2859	117	115	0.65	0.65	NUM
admet-2859	117	116	0.44	0.44	NUM
admet-2859	117	117	0.44	0.44	NUM
admet-2859	117	118	0.65	0.65	NUM
admet-2859	117	119	0.65	0.65	NUM
admet-2859	117	120	0.44	0.44	NUM
admet-2859	117	121	0.44	0.44	NUM
admet-2859	117	122	huwl	huwl	NOUN
admet-2859	117	123	donor	donor	NOUN
admet-2859	117	124	/	/	SYM
admet-2859	117	125	µm	µm	ADP
admet-2859	117	126	183	183	NUM
admet-2859	117	127	26	26	NUM
admet-2859	117	128	183	183	NUM
admet-2859	117	129	26	26	NUM
admet-2859	117	130	183	183	NUM
admet-2859	117	131	26	26	NUM
admet-2859	117	132	183	183	NUM
admet-2859	117	133	26	26	NUM
admet-2859	117	134	183	183	NUM
admet-2859	117	135	26	26	NUM
admet-2859	117	136	183	183	NUM
admet-2859	117	137	26	26	NUM
admet-2859	117	138	huwl	huwl	NOUN
admet-2859	117	139	acceptor	acceptor	NOUN
admet-2859	117	140	/	/	SYM
admet-2859	117	141	µm	µm	NOUN
admet-2859	117	142	183	183	NUM
admet-2859	117	143	183	183	NUM
admet-2859	117	144	26	26	NUM
admet-2859	117	145	26	26	NUM
admet-2859	117	146	183	183	NUM
admet-2859	117	147	183	183	NUM
admet-2859	117	148	26	26	NUM
admet-2859	117	149	26	26	NUM
admet-2859	117	150	183	183	NUM
admet-2859	117	151	183	183	NUM
admet-2859	117	152	26	26	NUM
admet-2859	117	153	26	26	NUM
admet-2859	117	154	*	*	PUNCT
admet-2859	117	155	if	if	SCONJ
admet-2859	117	156	puwl	puwl	X
admet-2859	117	157	<	<	X
admet-2859	117	158	pm	pm	NOUN
admet-2859	117	159	then	then	ADV
admet-2859	117	160	the	the	DET
admet-2859	117	161	system	system	NOUN
admet-2859	117	162	tends	tend	VERB
admet-2859	117	163	towards	towards	ADP
admet-2859	117	164	uwl	uwl	NOUN
admet-2859	117	165	limitation	limitation	NOUN
admet-2859	117	166	,	,	PUNCT
admet-2859	117	167	these	these	DET
admet-2859	117	168	cases	case	NOUN
admet-2859	117	169	have	have	VERB
admet-2859	117	170	blue	blue	ADJ
admet-2859	117	171	background	background	NOUN
admet-2859	117	172	;	;	PUNCT
admet-2859	117	173	if	if	SCONJ
admet-2859	117	174	puwl	puwl	X
admet-2859	117	175	>	>	PUNCT
admet-2859	117	176	pm	pm	NOUN
admet-2859	117	177	then	then	ADV
admet-2859	117	178	the	the	DET
admet-2859	117	179	system	system	NOUN
admet-2859	117	180	tends	tend	VERB
admet-2859	117	181	towards	towards	ADP
admet-2859	117	182	membrane	membrane	NOUN
admet-2859	117	183	limitation	limitation	NOUN
admet-2859	117	184	,	,	PUNCT
admet-2859	117	185	these	these	DET
admet-2859	117	186	cases	case	NOUN
admet-2859	117	187	have	have	VERB
admet-2859	117	188	green	green	ADJ
admet-2859	117	189	background	background	NOUN
admet-2859	117	190	;	;	PUNCT
admet-2859	117	191	if	if	SCONJ
admet-2859	117	192	there	there	PRON
admet-2859	117	193	was	be	VERB
admet-2859	117	194	no	no	DET
admet-2859	117	195	significant	significant	ADJ
admet-2859	117	196	difference	difference	NOUN
admet-2859	117	197	found	find	VERB
admet-2859	117	198	between	between	ADP
admet-2859	117	199	the	the	DET
admet-2859	117	200	pm	pm	NOUN
admet-2859	117	201	and	and	CCONJ
admet-2859	117	202	puwl	puwl	ADJ
admet-2859	117	203	values	value	NOUN
admet-2859	117	204	then	then	ADV
admet-2859	117	205	beige	beige	ADJ
admet-2859	117	206	background	background	NOUN
admet-2859	117	207	was	be	AUX
admet-2859	117	208	used	use	VERB
admet-2859	117	209	.	.	PUNCT
admet-2859	118	1	from	from	ADP
admet-2859	118	2	the	the	DET
admet-2859	118	3	results	result	NOUN
admet-2859	118	4	in	in	ADP
admet-2859	118	5	table	table	NOUN
admet-2859	118	6	3	3	NUM
admet-2859	118	7	it	it	PRON
admet-2859	118	8	can	can	AUX
admet-2859	118	9	be	be	AUX
admet-2859	118	10	concluded	conclude	VERB
admet-2859	118	11	that	that	SCONJ
admet-2859	118	12	,	,	PUNCT
admet-2859	118	13	when	when	SCONJ
admet-2859	118	14	only	only	ADV
admet-2859	118	15	plain	plain	ADJ
admet-2859	118	16	ph	ph	ADJ
admet-2859	118	17	10	10	NUM
admet-2859	118	18	media	medium	NOUN
admet-2859	118	19	is	be	AUX
admet-2859	118	20	used	use	VERB
admet-2859	118	21	on	on	ADP
admet-2859	118	22	both	both	DET
admet-2859	118	23	sides	side	NOUN
admet-2859	118	24	of	of	ADP
admet-2859	118	25	the	the	DET
admet-2859	118	26	lipophilic	lipophilic	ADJ
admet-2859	118	27	membrane	membrane	NOUN
admet-2859	118	28	,	,	PUNCT
admet-2859	118	29	then	then	ADV
admet-2859	118	30	the	the	DET
admet-2859	118	31	membrane	membrane	NOUN
admet-2859	118	32	transport	transport	NOUN
admet-2859	118	33	is	be	AUX
admet-2859	118	34	uwl	uwl	ADV
admet-2859	118	35	limited	limit	VERB
admet-2859	118	36	.	.	PUNCT
admet-2859	119	1	when	when	SCONJ
admet-2859	119	2	hp	hp	PROPN
admet-2859	119	3	-	-	PUNCT
admet-2859	119	4	β	β	NOUN
admet-2859	119	5	-	-	NOUN
admet-2859	119	6	cd	cd	PROPN
admet-2859	119	7	is	be	AUX
admet-2859	119	8	placed	place	VERB
admet-2859	119	9	on	on	ADP
admet-2859	119	10	the	the	DET
admet-2859	119	11	acceptor	acceptor	NOUN
admet-2859	119	12	a	a	DET
admet-2859	119	13	p	p	X
admet-2859	119	14	p	p	X
admet-2859	119	15	a	a	DET
admet-2859	119	16	r	r	NOUN
admet-2859	119	17	e	e	NOUN
admet-2859	119	18	n	n	NOUN
admet-2859	119	19	t	t	NOUN
admet-2859	119	20	p	p	X
admet-2859	120	1	e	e	PROPN
admet-2859	120	2	r	r	NOUN
admet-2859	120	3	m	m	PROPN
admet-2859	120	4	e	e	NOUN
admet-2859	120	5	a	a	PRON
admet-2859	120	6	b	b	X
admet-2859	120	7	il	il	INTJ
admet-2859	120	8	it	it	PRON
admet-2859	120	9	y	y	PROPN
admet-2859	120	10	,	,	PUNCT
admet-2859	120	11	cm	cm	PROPN
admet-2859	120	12	s	s	PART
admet-2859	120	13	-1	-1	NOUN
admet-2859	120	14	a	a	DET
admet-2859	120	15	p	p	X
admet-2859	120	16	p	p	X
admet-2859	120	17	a	a	DET
admet-2859	120	18	r	r	NOUN
admet-2859	120	19	e	e	NOUN
admet-2859	120	20	n	n	NOUN
admet-2859	120	21	t	t	NOUN
admet-2859	120	22	p	p	X
admet-2859	121	1	e	e	PROPN
admet-2859	121	2	r	r	NOUN
admet-2859	121	3	m	m	PROPN
admet-2859	121	4	e	e	NOUN
admet-2859	121	5	a	a	PRON
admet-2859	121	6	b	b	X
admet-2859	121	7	il	il	INTJ
admet-2859	121	8	it	it	PRON
admet-2859	121	9	y	y	PROPN
admet-2859	121	10	,	,	PUNCT
admet-2859	121	11	cm	cm	PROPN
admet-2859	121	12	s	s	PART
admet-2859	121	13	-1	-1	NOUN
admet-2859	121	14	a	a	DET
admet-2859	121	15	p	p	X
admet-2859	121	16	p	p	X
admet-2859	121	17	a	a	DET
admet-2859	121	18	r	r	NOUN
admet-2859	121	19	e	e	NOUN
admet-2859	121	20	n	n	NOUN
admet-2859	121	21	t	t	NOUN
admet-2859	121	22	p	p	X
admet-2859	122	1	e	e	PROPN
admet-2859	122	2	r	r	NOUN
admet-2859	122	3	m	m	PROPN
admet-2859	122	4	e	e	NOUN
admet-2859	122	5	a	a	PRON
admet-2859	122	6	b	b	X
admet-2859	122	7	il	il	INTJ
admet-2859	122	8	it	it	PRON
admet-2859	122	9	y	y	PROPN
admet-2859	122	10	,	,	PUNCT
admet-2859	122	11	cm	cm	PROPN
admet-2859	122	12	s	s	PART
admet-2859	122	13	-1	-1	NOUN
admet-2859	122	14	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	PROPN
admet-2859	122	15	p.	p.	NOUN
admet-2859	122	16	tőzsér	tőzsér	PROPN
admet-2859	122	17	et	et	PROPN
admet-2859	122	18	al	al	PROPN
admet-2859	122	19	.	.	PROPN
admet-2859	122	20	admet	admet	PROPN
admet-2859	122	21	&	&	CCONJ
admet-2859	122	22	dmpk	dmpk	PROPN
admet-2859	122	23	13(5	13(5	NUM
admet-2859	122	24	)	)	PUNCT
admet-2859	122	25	(	(	PUNCT
admet-2859	122	26	2025	2025	NUM
admet-2859	122	27	)	)	PUNCT
admet-2859	122	28	2859	2859	NUM
admet-2859	122	29	8	8	NUM
admet-2859	122	30	side	side	NOUN
admet-2859	122	31	,	,	PUNCT
admet-2859	122	32	then	then	ADV
admet-2859	122	33	the	the	DET
admet-2859	122	34	diffusion	diffusion	NOUN
admet-2859	122	35	through	through	ADP
admet-2859	122	36	the	the	DET
admet-2859	122	37	membrane	membrane	NOUN
admet-2859	122	38	and	and	CCONJ
admet-2859	122	39	the	the	DET
admet-2859	122	40	uwl	uwl	NOUN
admet-2859	122	41	have	have	VERB
admet-2859	122	42	similar	similar	ADJ
admet-2859	122	43	speed	speed	NOUN
admet-2859	122	44	,	,	PUNCT
admet-2859	122	45	and	and	CCONJ
admet-2859	122	46	when	when	SCONJ
admet-2859	122	47	both	both	DET
admet-2859	122	48	compartments	compartment	NOUN
admet-2859	122	49	contain	contain	VERB
admet-2859	122	50	the	the	DET
admet-2859	122	51	complexing	complexe	VERB
admet-2859	122	52	agent	agent	NOUN
admet-2859	122	53	,	,	PUNCT
admet-2859	122	54	then	then	ADV
admet-2859	122	55	the	the	DET
admet-2859	122	56	transport	transport	NOUN
admet-2859	122	57	becomes	become	VERB
admet-2859	122	58	membrane	membrane	NOUN
admet-2859	122	59	-	-	PUNCT
admet-2859	122	60	limited	limit	VERB
admet-2859	122	61	.	.	PUNCT
admet-2859	123	1	in	in	ADP
admet-2859	123	2	case	case	NOUN
admet-2859	123	3	of	of	ADP
admet-2859	123	4	size	size	NOUN
admet-2859	123	5	-	-	PUNCT
admet-2859	123	6	exclusion	exclusion	NOUN
admet-2859	123	7	membranes	membrane	NOUN
admet-2859	123	8	,	,	PUNCT
admet-2859	123	9	regardless	regardless	ADV
admet-2859	123	10	of	of	ADP
admet-2859	123	11	the	the	DET
admet-2859	123	12	mwco	mwco	NOUN
admet-2859	123	13	,	,	PUNCT
admet-2859	123	14	the	the	DET
admet-2859	123	15	limiting	limit	VERB
admet-2859	123	16	step	step	NOUN
admet-2859	123	17	of	of	ADP
admet-2859	123	18	transport	transport	NOUN
admet-2859	123	19	is	be	AUX
admet-2859	123	20	the	the	DET
admet-2859	123	21	diffusion	diffusion	NOUN
admet-2859	123	22	through	through	ADP
admet-2859	123	23	the	the	DET
admet-2859	123	24	water	water	NOUN
admet-2859	123	25	-	-	PUNCT
admet-2859	123	26	filled	fill	VERB
admet-2859	123	27	membrane	membrane	NOUN
admet-2859	123	28	.	.	PUNCT
admet-2859	124	1	this	this	PRON
admet-2859	124	2	holds	hold	VERB
admet-2859	124	3	for	for	ADP
admet-2859	124	4	all	all	DET
admet-2859	124	5	experimental	experimental	ADJ
admet-2859	124	6	scenarios	scenario	NOUN
admet-2859	124	7	:	:	PUNCT
admet-2859	124	8	when	when	SCONJ
admet-2859	124	9	no	no	DET
admet-2859	124	10	hp	hp	NOUN
admet-2859	124	11	-	-	PUNCT
admet-2859	124	12	β	β	NOUN
admet-2859	124	13	-	-	NOUN
admet-2859	124	14	cd	cd	NOUN
admet-2859	124	15	is	be	AUX
admet-2859	124	16	present	present	ADJ
admet-2859	124	17	on	on	ADP
admet-2859	124	18	either	either	DET
admet-2859	124	19	side	side	NOUN
admet-2859	124	20	(	(	PUNCT
admet-2859	124	21	table	table	NOUN
admet-2859	124	22	3	3	NUM
admet-2859	124	23	cdnone	cdnone	NOUN
admet-2859	124	24	)	)	PUNCT
admet-2859	124	25	,	,	PUNCT
admet-2859	124	26	when	when	SCONJ
admet-2859	124	27	hp	hp	VERB
admet-2859	124	28	-	-	PUNCT
admet-2859	124	29	β	β	NOUN
admet-2859	124	30	-	-	NOUN
admet-2859	124	31	cd	cd	NOUN
admet-2859	124	32	is	be	AUX
admet-2859	124	33	present	present	ADJ
admet-2859	124	34	on	on	ADP
admet-2859	124	35	the	the	DET
admet-2859	124	36	donor	donor	NOUN
admet-2859	124	37	side	side	NOUN
admet-2859	124	38	(	(	PUNCT
admet-2859	124	39	table	table	NOUN
admet-2859	124	40	3	3	NUM
admet-2859	124	41	cd	cd	NOUN
admet-2859	124	42	-	-	PUNCT
admet-2859	124	43	donor	donor	NOUN
admet-2859	124	44	)	)	PUNCT
admet-2859	124	45	,	,	PUNCT
admet-2859	124	46	when	when	SCONJ
admet-2859	124	47	hp	hp	VERB
admet-2859	124	48	-	-	PUNCT
admet-2859	124	49	β	β	NOUN
admet-2859	124	50	-	-	NOUN
admet-2859	124	51	cd	cd	NOUN
admet-2859	124	52	is	be	AUX
admet-2859	124	53	present	present	ADJ
admet-2859	124	54	on	on	ADP
admet-2859	124	55	the	the	DET
admet-2859	124	56	acceptor	acceptor	NOUN
admet-2859	124	57	side	side	NOUN
admet-2859	124	58	(	(	PUNCT
admet-2859	124	59	table	table	NOUN
admet-2859	124	60	3	3	NUM
admet-2859	124	61	cd	cd	NOUN
admet-2859	124	62	-	-	PUNCT
admet-2859	124	63	acceptor	acceptor	NOUN
admet-2859	124	64	)	)	PUNCT
admet-2859	124	65	,	,	PUNCT
admet-2859	124	66	and	and	CCONJ
admet-2859	124	67	when	when	SCONJ
admet-2859	124	68	hp	hp	VERB
admet-2859	124	69	-	-	PUNCT
admet-2859	124	70	β	β	NOUN
admet-2859	124	71	-	-	NOUN
admet-2859	124	72	cd	cd	NOUN
admet-2859	124	73	is	be	AUX
admet-2859	124	74	present	present	ADJ
admet-2859	124	75	on	on	ADP
admet-2859	124	76	both	both	DET
admet-2859	124	77	sides	side	NOUN
admet-2859	124	78	of	of	ADP
admet-2859	124	79	the	the	DET
admet-2859	124	80	membrane	membrane	NOUN
admet-2859	124	81	(	(	PUNCT
admet-2859	124	82	table	table	NOUN
admet-2859	124	83	3	3	NUM
admet-2859	124	84	cd	cd	NOUN
admet-2859	124	85	-	-	PUNCT
admet-2859	124	86	both	both	PRON
admet-2859	124	87	)	)	PUNCT
admet-2859	124	88	.	.	PUNCT
admet-2859	125	1	discussion	discussion	NOUN
admet-2859	125	2	of	of	ADP
admet-2859	125	3	the	the	DET
admet-2859	125	4	driving	drive	VERB
admet-2859	125	5	force	force	NOUN
admet-2859	125	6	of	of	ADP
admet-2859	125	7	membrane	membrane	NOUN
admet-2859	125	8	transport	transport	NOUN
admet-2859	125	9	in	in	ADP
admet-2859	125	10	case	case	NOUN
admet-2859	125	11	of	of	ADP
admet-2859	125	12	sink	sink	NOUN
admet-2859	125	13	condition	condition	NOUN
admet-2859	125	14	in	in	ADP
admet-2859	125	15	this	this	DET
admet-2859	125	16	section	section	NOUN
admet-2859	125	17	,	,	PUNCT
admet-2859	125	18	the	the	DET
admet-2859	125	19	aim	aim	NOUN
admet-2859	125	20	was	be	AUX
admet-2859	125	21	to	to	PART
admet-2859	125	22	assess	assess	VERB
admet-2859	125	23	the	the	DET
admet-2859	125	24	applicability	applicability	NOUN
admet-2859	125	25	of	of	ADP
admet-2859	125	26	a	a	DET
admet-2859	125	27	previously	previously	ADV
admet-2859	125	28	described	describe	VERB
admet-2859	125	29	general	general	ADJ
admet-2859	125	30	mathematical	mathematical	ADJ
admet-2859	125	31	equation	equation	NOUN
admet-2859	125	32	(	(	PUNCT
admet-2859	125	33	1	1	NUM
admet-2859	125	34	)	)	PUNCT
admet-2859	125	35	under	under	ADP
admet-2859	125	36	sink	sink	NOUN
admet-2859	125	37	conditions	condition	NOUN
admet-2859	125	38	.	.	PUNCT
admet-2859	126	1	this	this	DET
admet-2859	126	2	equation	equation	NOUN
admet-2859	126	3	was	be	AUX
admet-2859	126	4	formulated	formulate	VERB
admet-2859	126	5	to	to	PART
admet-2859	126	6	describe	describe	VERB
admet-2859	126	7	the	the	DET
admet-2859	126	8	transport	transport	NOUN
admet-2859	126	9	across	across	ADP
admet-2859	126	10	the	the	DET
admet-2859	126	11	uwlmembrane	uwlmembrane	NOUN
admet-2859	126	12	-	-	PUNCT
admet-2859	126	13	uwl	uwl	NOUN
admet-2859	126	14	system	system	NOUN
admet-2859	126	15	in	in	ADP
admet-2859	126	16	a	a	DET
admet-2859	126	17	general	general	ADJ
admet-2859	126	18	way	way	NOUN
admet-2859	126	19	(	(	PUNCT
admet-2859	126	20	equation	equation	NOUN
admet-2859	126	21	(	(	PUNCT
admet-2859	126	22	2	2	NUM
admet-2859	126	23	)	)	PUNCT
admet-2859	126	24	)	)	PUNCT
admet-2859	126	25	,	,	PUNCT
admet-2859	126	26	without	without	ADP
admet-2859	126	27	defining	define	VERB
admet-2859	126	28	the	the	DET
admet-2859	126	29	specific	specific	ADJ
admet-2859	126	30	type	type	NOUN
admet-2859	126	31	of	of	ADP
admet-2859	126	32	membrane	membrane	NOUN
admet-2859	126	33	located	locate	VERB
admet-2859	126	34	between	between	ADP
admet-2859	126	35	the	the	DET
admet-2859	126	36	two	two	NUM
admet-2859	126	37	uwl	uwl	NOUN
admet-2859	126	38	layers	layer	NOUN
admet-2859	126	39	or	or	CCONJ
admet-2859	126	40	specifying	specify	VERB
admet-2859	126	41	the	the	DET
admet-2859	126	42	limiting	limit	VERB
admet-2859	126	43	step	step	NOUN
admet-2859	126	44	of	of	ADP
admet-2859	126	45	transport	transport	NOUN
admet-2859	126	46	.	.	PUNCT
admet-2859	127	1	experimental	experimental	ADJ
admet-2859	127	2	results	result	NOUN
admet-2859	127	3	confirmed	confirm	VERB
admet-2859	127	4	the	the	DET
admet-2859	127	5	applicability	applicability	NOUN
admet-2859	127	6	of	of	ADP
admet-2859	127	7	the	the	DET
admet-2859	127	8	model	model	NOUN
admet-2859	127	9	when	when	SCONJ
admet-2859	127	10	the	the	DET
admet-2859	127	11	membrane	membrane	NOUN
admet-2859	127	12	is	be	AUX
admet-2859	127	13	selectively	selectively	ADV
admet-2859	127	14	permeable	permeable	ADJ
admet-2859	127	15	for	for	ADP
admet-2859	127	16	the	the	DET
admet-2859	127	17	drug	drug	NOUN
admet-2859	127	18	(	(	PUNCT
admet-2859	127	19	lipophilic	lipophilic	ADJ
admet-2859	127	20	membrane	membrane	NOUN
admet-2859	127	21	)	)	PUNCT
admet-2859	127	22	or	or	CCONJ
admet-2859	127	23	when	when	SCONJ
admet-2859	127	24	the	the	DET
admet-2859	127	25	permeation	permeation	NOUN
admet-2859	127	26	of	of	ADP
admet-2859	127	27	the	the	DET
admet-2859	127	28	solubilizing	solubilizing	NOUN
admet-2859	127	29	additive	additive	NOUN
admet-2859	127	30	is	be	AUX
admet-2859	127	31	negligibly	negligibly	ADV
admet-2859	127	32	slow	slow	ADJ
admet-2859	127	33	(	(	PUNCT
admet-2859	127	34	1	1	NUM
admet-2859	127	35	kda	kda	NOUN
admet-2859	127	36	mwco	mwco	NOUN
admet-2859	127	37	)	)	PUNCT
admet-2859	128	1	[	[	X
admet-2859	128	2	1	1	NUM
admet-2859	128	3	]	]	PUNCT
admet-2859	128	4	.	.	PUNCT
admet-2859	129	1	the	the	DET
admet-2859	129	2	mathematical	mathematical	ADJ
admet-2859	129	3	model	model	NOUN
admet-2859	129	4	is	be	AUX
admet-2859	129	5	now	now	ADV
admet-2859	129	6	applied	apply	VERB
admet-2859	129	7	in	in	ADP
admet-2859	129	8	cases	case	NOUN
admet-2859	129	9	where	where	SCONJ
admet-2859	129	10	the	the	DET
admet-2859	129	11	solubilizing	solubilizing	NOUN
admet-2859	129	12	additive	additive	NOUN
admet-2859	129	13	is	be	AUX
admet-2859	129	14	placed	place	VERB
admet-2859	129	15	on	on	ADP
admet-2859	129	16	the	the	DET
admet-2859	129	17	acceptor	acceptor	NOUN
admet-2859	129	18	side	side	NOUN
admet-2859	129	19	to	to	PART
admet-2859	129	20	create	create	VERB
admet-2859	129	21	sink	sink	NOUN
admet-2859	129	22	conditions	condition	NOUN
admet-2859	129	23	,	,	PUNCT
admet-2859	129	24	or	or	CCONJ
admet-2859	129	25	where	where	SCONJ
admet-2859	129	26	the	the	DET
admet-2859	129	27	cd	cd	PROPN
admet-2859	129	28	is	be	AUX
admet-2859	129	29	added	add	VERB
admet-2859	129	30	to	to	ADP
admet-2859	129	31	both	both	DET
admet-2859	129	32	sides	side	NOUN
admet-2859	129	33	of	of	ADP
admet-2859	129	34	the	the	DET
admet-2859	129	35	lipophilic	lipophilic	ADJ
admet-2859	129	36	and	and	CCONJ
admet-2859	129	37	size	size	NOUN
admet-2859	129	38	-	-	PUNCT
admet-2859	129	39	exclusion	exclusion	NOUN
admet-2859	129	40	membranes	membrane	NOUN
admet-2859	129	41	.	.	PUNCT
admet-2859	130	1	d	d	X
admet-2859	130	2	a	a	DET
admet-2859	130	3	e	e	X
admet-2859	130	4	d	d	X
admet-2859	130	5	a	a	PRON
admet-2859	130	6	  	  	SPACE
admet-2859	130	7	*	*	PUNCT
admet-2859	131	1	*	*	PUNCT
admet-2859	131	2	c	c	NOUN
admet-2859	131	3	c	c	PROPN
admet-2859	131	4	j	j	PROPN
admet-2859	132	1	b	b	PROPN
admet-2859	132	2	c	c	PROPN
admet-2859	132	3	c	c	PROPN
admet-2859	132	4			NOUN
admet-2859	132	5			NOUN
admet-2859	132	6	=	=	PUNCT
admet-2859	133	1	−	−	PROPN
admet-2859	133	2			PROPN
admet-2859	134	1			PROPN
admet-2859	134	2			NOUN
admet-2859	134	3	(	(	PUNCT
admet-2859	134	4	2	2	NUM
admet-2859	134	5	)	)	PUNCT
admet-2859	134	6	where	where	SCONJ
admet-2859	134	7	j	j	PROPN
admet-2859	134	8	is	be	AUX
admet-2859	134	9	the	the	DET
admet-2859	134	10	flux	flux	NOUN
admet-2859	134	11	,	,	PUNCT
admet-2859	134	12	be	be	AUX
admet-2859	134	13	is	be	AUX
admet-2859	134	14	the	the	DET
admet-2859	134	15	effective	effective	ADJ
admet-2859	134	16	coefficient	coefficient	NOUN
admet-2859	134	17	of	of	ADP
admet-2859	134	18	proportionality	proportionality	NOUN
admet-2859	134	19	,	,	PUNCT
admet-2859	134	20	cd	cd	PROPN
admet-2859	134	21	and	and	CCONJ
admet-2859	134	22	ca	can	AUX
admet-2859	134	23	are	be	AUX
admet-2859	134	24	the	the	DET
admet-2859	134	25	concentrations	concentration	NOUN
admet-2859	134	26	,	,	PUNCT
admet-2859	134	27	and	and	CCONJ
admet-2859	134	28	cd	cd	PROPN
admet-2859	134	29	*	*	PROPN
admet-2859	134	30	and	and	CCONJ
admet-2859	134	31	ca	can	AUX
admet-2859	134	32	*	*	NOUN
admet-2859	134	33	are	be	AUX
admet-2859	134	34	the	the	DET
admet-2859	134	35	solubility	solubility	NOUN
admet-2859	134	36	values	value	NOUN
admet-2859	134	37	in	in	ADP
admet-2859	134	38	the	the	DET
admet-2859	134	39	donor	donor	NOUN
admet-2859	134	40	and	and	CCONJ
admet-2859	134	41	acceptor	acceptor	NOUN
admet-2859	134	42	media	medium	NOUN
admet-2859	135	1	[	[	X
admet-2859	135	2	1	1	NUM
admet-2859	135	3	]	]	PUNCT
admet-2859	135	4	.	.	PUNCT
admet-2859	136	1	equation	equation	NOUN
admet-2859	136	2	(	(	PUNCT
admet-2859	136	3	2	2	X
admet-2859	136	4	)	)	PUNCT
admet-2859	136	5	indicates	indicate	VERB
admet-2859	136	6	that	that	SCONJ
admet-2859	136	7	the	the	DET
admet-2859	136	8	driving	drive	VERB
admet-2859	136	9	force	force	NOUN
admet-2859	136	10	of	of	ADP
admet-2859	136	11	membrane	membrane	NOUN
admet-2859	136	12	transport	transport	NOUN
admet-2859	136	13	is	be	AUX
admet-2859	136	14	a	a	DET
admet-2859	136	15	difference	difference	NOUN
admet-2859	136	16	in	in	ADP
admet-2859	136	17	the	the	DET
admet-2859	136	18	supersaturation	supersaturation	NOUN
admet-2859	136	19	ratio	ratio	NOUN
admet-2859	136	20	(	(	PUNCT
admet-2859	136	21	ssr	ssr	PROPN
admet-2859	136	22	)	)	PUNCT
admet-2859	136	23	between	between	ADP
admet-2859	136	24	the	the	DET
admet-2859	136	25	donor	donor	NOUN
admet-2859	136	26	and	and	CCONJ
admet-2859	136	27	acceptor	acceptor	NOUN
admet-2859	136	28	compartments	compartment	NOUN
admet-2859	136	29	.	.	PUNCT
admet-2859	137	1	this	this	DET
admet-2859	137	2	difference	difference	NOUN
admet-2859	137	3	is	be	AUX
admet-2859	137	4	directly	directly	ADV
admet-2859	137	5	proportional	proportional	ADJ
admet-2859	137	6	to	to	ADP
admet-2859	137	7	the	the	DET
admet-2859	137	8	flux	flux	NOUN
admet-2859	137	9	and	and	CCONJ
admet-2859	137	10	the	the	DET
admet-2859	137	11	coefficient	coefficient	NOUN
admet-2859	137	12	of	of	ADP
admet-2859	137	13	proportionality	proportionality	NOUN
admet-2859	137	14	,	,	PUNCT
admet-2859	137	15	be	be	AUX
admet-2859	137	16	.	.	PUNCT
admet-2859	138	1	equation	equation	NOUN
admet-2859	138	2	(	(	PUNCT
admet-2859	138	3	3	3	X
admet-2859	138	4	)	)	PUNCT
admet-2859	138	5	describes	describe	VERB
admet-2859	138	6	the	the	DET
admet-2859	138	7	reciprocal	reciprocal	ADJ
admet-2859	138	8	relationship	relationship	NOUN
admet-2859	138	9	between	between	ADP
admet-2859	138	10	the	the	DET
admet-2859	138	11	coefficients	coefficient	NOUN
admet-2859	138	12	of	of	ADP
admet-2859	138	13	proportionality	proportionality	NOUN
admet-2859	139	1	[	[	X
admet-2859	139	2	1	1	NUM
admet-2859	139	3	]	]	X
admet-2859	139	4	:	:	PUNCT
admet-2859	139	5	uwl	uwl	X
admet-2859	139	6	,	,	PUNCT
admet-2859	139	7	eff	eff	PROPN
admet-2859	139	8	uwl	uwl	AUX
admet-2859	139	9	m	m	VERB
admet-2859	139	10	me	i	PRON
admet-2859	139	11	uwl	uwl	AUX
admet-2859	139	12	m	m	VERB
admet-2859	139	13	muwl	muwl	PROPN
admet-2859	139	14	,	,	PUNCT
admet-2859	139	15	eff	eff	PROPN
admet-2859	139	16	1	1	NUM
admet-2859	139	17	1	1	NUM
admet-2859	139	18	1	1	NUM
admet-2859	139	19	1	1	NUM
admet-2859	139	20	1	1	NUM
admet-2859	139	21	*	*	PUNCT
admet-2859	139	22	*	*	PUNCT
admet-2859	139	23	d	d	X
admet-2859	139	24	c	c	PROPN
admet-2859	139	25	d	d	X
admet-2859	139	26	cb	cb	PROPN
admet-2859	139	27	b	b	PROPN
admet-2859	139	28	b	b	NOUN
admet-2859	139	29	hh	hh	NOUN
admet-2859	140	1	=	=	PUNCT
admet-2859	140	2	+	+	PUNCT
admet-2859	140	3	=	=	SYM
admet-2859	140	4	+	+	CCONJ
admet-2859	140	5	(	(	PUNCT
admet-2859	140	6	3	3	NUM
admet-2859	140	7	)	)	PUNCT
admet-2859	140	8	where	where	SCONJ
admet-2859	140	9	buwl	buwl	NOUN
admet-2859	140	10	 	 	SPACE
admet-2859	140	11	is	be	AUX
admet-2859	140	12	the	the	DET
admet-2859	140	13	b	b	NOUN
admet-2859	140	14	factor	factor	NOUN
admet-2859	140	15	for	for	ADP
admet-2859	140	16	the	the	DET
admet-2859	140	17	uwl	uwl	NOUN
admet-2859	140	18	and	and	CCONJ
admet-2859	140	19	bm	bm	PROPN
admet-2859	140	20	is	be	AUX
admet-2859	140	21	the	the	DET
admet-2859	140	22	b	b	PROPN
admet-2859	140	23	factor	factor	NOUN
admet-2859	140	24	for	for	ADP
admet-2859	140	25	the	the	DET
admet-2859	140	26	membrane	membrane	NOUN
admet-2859	140	27	,	,	PUNCT
admet-2859	140	28	duwl	duwl	PROPN
admet-2859	140	29	,	,	PUNCT
admet-2859	140	30	eff	eff	PROPN
admet-2859	140	31	is	be	AUX
admet-2859	140	32	the	the	DET
admet-2859	140	33	effective	effective	ADJ
admet-2859	140	34	diffusion	diffusion	NOUN
admet-2859	140	35	coefficient	coefficient	NOUN
admet-2859	140	36	through	through	ADP
admet-2859	140	37	the	the	DET
admet-2859	140	38	uwl	uwl	NOUN
admet-2859	140	39	and	and	CCONJ
admet-2859	140	40	huwl	huwl	NOUN
admet-2859	140	41	,	,	PUNCT
admet-2859	140	42	eff	eff	PROPN
admet-2859	140	43	is	be	AUX
admet-2859	140	44	the	the	DET
admet-2859	140	45	effective	effective	ADJ
admet-2859	140	46	thickness	thickness	NOUN
admet-2859	140	47	of	of	ADP
admet-2859	140	48	the	the	DET
admet-2859	140	49	uwl	uwl	NOUN
admet-2859	140	50	in	in	ADP
admet-2859	140	51	the	the	DET
admet-2859	140	52	presence	presence	NOUN
admet-2859	140	53	of	of	ADP
admet-2859	140	54	hpβ	hpβ	NOUN
admet-2859	140	55	-	-	PUNCT
admet-2859	140	56	cd	cd	PROPN
admet-2859	140	57	and	and	CCONJ
admet-2859	140	58	cuwl	cuwl	NOUN
admet-2859	140	59	is	be	AUX
admet-2859	140	60	the	the	DET
admet-2859	140	61	concentration	concentration	NOUN
admet-2859	140	62	of	of	ADP
admet-2859	140	63	the	the	DET
admet-2859	140	64	api	api	NOUN
admet-2859	140	65	in	in	ADP
admet-2859	140	66	the	the	DET
admet-2859	140	67	uwl	uwl	NOUN
admet-2859	140	68	,	,	PUNCT
admet-2859	140	69	and	and	CCONJ
admet-2859	140	70	*	*	PUNCT
admet-2859	140	71	is	be	AUX
admet-2859	140	72	the	the	DET
admet-2859	140	73	property	property	NOUN
admet-2859	140	74	at	at	ADP
admet-2859	140	75	saturation	saturation	NOUN
admet-2859	140	76	,	,	PUNCT
admet-2859	140	77	dm	dm	PROPN
admet-2859	140	78	is	be	AUX
admet-2859	140	79	the	the	DET
admet-2859	140	80	diffusion	diffusion	NOUN
admet-2859	140	81	coefficient	coefficient	NOUN
admet-2859	140	82	through	through	ADP
admet-2859	140	83	the	the	DET
admet-2859	140	84	membrane	membrane	NOUN
admet-2859	140	85	,	,	PUNCT
admet-2859	140	86	cm	cm	PROPN
admet-2859	140	87	is	be	AUX
admet-2859	140	88	the	the	DET
admet-2859	140	89	concentration	concentration	NOUN
admet-2859	140	90	of	of	ADP
admet-2859	140	91	the	the	DET
admet-2859	140	92	drug	drug	NOUN
admet-2859	140	93	in	in	ADP
admet-2859	140	94	the	the	DET
admet-2859	140	95	membrane	membrane	NOUN
admet-2859	140	96	and	and	CCONJ
admet-2859	140	97	*	*	NOUN
admet-2859	140	98	is	be	AUX
admet-2859	140	99	the	the	DET
admet-2859	140	100	property	property	NOUN
admet-2859	140	101	at	at	ADP
admet-2859	140	102	saturation	saturation	NOUN
admet-2859	140	103	,	,	PUNCT
admet-2859	140	104	hm	hm	INTJ
admet-2859	140	105	is	be	AUX
admet-2859	140	106	the	the	DET
admet-2859	140	107	membrane	membrane	NOUN
admet-2859	140	108	thickness	thickness	NOUN
admet-2859	140	109	.	.	PUNCT
admet-2859	141	1	figure	figure	NOUN
admet-2859	141	2	5	5	NUM
admet-2859	141	3	shows	show	VERB
admet-2859	141	4	the	the	DET
admet-2859	141	5	flux	flux	NOUN
admet-2859	141	6	plotted	plot	VERB
admet-2859	141	7	as	as	ADP
admet-2859	141	8	a	a	DET
admet-2859	141	9	function	function	NOUN
admet-2859	141	10	of	of	ADP
admet-2859	141	11	the	the	DET
admet-2859	141	12	difference	difference	NOUN
admet-2859	141	13	in	in	ADP
admet-2859	141	14	ssr	ssr	PROPN
admet-2859	141	15	.	.	PUNCT
admet-2859	142	1	the	the	DET
admet-2859	142	2	slopes	slope	NOUN
admet-2859	142	3	of	of	ADP
admet-2859	142	4	the	the	DET
admet-2859	142	5	lines	line	NOUN
admet-2859	142	6	equal	equal	VERB
admet-2859	142	7	the	the	DET
admet-2859	142	8	coefficient	coefficient	NOUN
admet-2859	142	9	of	of	ADP
admet-2859	142	10	proportionality	proportionality	NOUN
admet-2859	142	11	.	.	PUNCT
admet-2859	143	1	homogeneity	homogeneity	NOUN
admet-2859	143	2	of	of	ADP
admet-2859	143	3	slopes	slope	NOUN
admet-2859	143	4	tests	test	NOUN
admet-2859	143	5	were	be	AUX
admet-2859	143	6	carried	carry	VERB
admet-2859	143	7	out	out	ADP
admet-2859	143	8	to	to	PART
admet-2859	143	9	see	see	VERB
admet-2859	143	10	if	if	SCONJ
admet-2859	143	11	the	the	DET
admet-2859	143	12	line	line	NOUN
admet-2859	143	13	of	of	ADP
admet-2859	143	14	the	the	DET
admet-2859	143	15	‘	'	PUNCT
admet-2859	143	16	cd	cd	NOUN
admet-2859	143	17	-	-	PUNCT
admet-2859	143	18	none	none	NOUN
admet-2859	143	19	’	'	PUNCT
admet-2859	143	20	buffer	buffer	NOUN
admet-2859	143	21	on	on	ADP
admet-2859	143	22	both	both	DET
admet-2859	143	23	sides	side	NOUN
admet-2859	143	24	(	(	PUNCT
admet-2859	143	25	red	red	ADJ
admet-2859	143	26	)	)	PUNCT
admet-2859	143	27	and	and	CCONJ
admet-2859	143	28	the	the	DET
admet-2859	143	29	hp	hp	PROPN
admet-2859	143	30	-	-	PUNCT
admet-2859	143	31	β	β	NOUN
admet-2859	143	32	-	-	ADJ
admet-2859	143	33	cd	cd	ADJ
admet-2859	143	34	containing	contain	VERB
admet-2859	143	35	buffer	buffer	NOUN
admet-2859	143	36	on	on	ADP
admet-2859	143	37	the	the	DET
admet-2859	143	38	acceptor	acceptor	NOUN
admet-2859	143	39	side	side	NOUN
admet-2859	143	40	(	(	PUNCT
admet-2859	143	41	purple	purple	ADJ
admet-2859	143	42	)	)	PUNCT
admet-2859	143	43	differ	differ	VERB
admet-2859	143	44	significantly	significantly	ADV
admet-2859	143	45	(	(	PUNCT
admet-2859	143	46	significance	significance	NOUN
admet-2859	143	47	:	:	PUNCT
admet-2859	143	48	p	p	X
admet-2859	143	49	<	<	X
admet-2859	143	50	0.05	0.05	NUM
admet-2859	143	51	)	)	PUNCT
admet-2859	143	52	.	.	PUNCT
admet-2859	144	1	the	the	DET
admet-2859	144	2	statistical	statistical	ADJ
admet-2859	144	3	analysis	analysis	NOUN
admet-2859	144	4	indicates	indicate	VERB
admet-2859	144	5	that	that	SCONJ
admet-2859	144	6	parallel	parallel	ADJ
admet-2859	144	7	lines	line	NOUN
admet-2859	144	8	are	be	AUX
admet-2859	144	9	obtained	obtain	VERB
admet-2859	144	10	by	by	ADP
admet-2859	144	11	size	size	NOUN
admet-2859	144	12	-	-	PUNCT
admet-2859	144	13	exclusion	exclusion	NOUN
admet-2859	144	14	membranes	membrane	NOUN
admet-2859	144	15	,	,	PUNCT
admet-2859	144	16	regardless	regardless	ADV
admet-2859	144	17	of	of	ADP
admet-2859	144	18	the	the	DET
admet-2859	144	19	mwco	mwco	NOUN
admet-2859	144	20	size	size	NOUN
admet-2859	144	21	of	of	ADP
admet-2859	144	22	the	the	DET
admet-2859	144	23	membrane	membrane	NOUN
admet-2859	144	24	(	(	PUNCT
admet-2859	144	25	refer	refer	VERB
admet-2859	144	26	to	to	ADP
admet-2859	144	27	p	p	NOUN
admet-2859	144	28	-	-	PUNCT
admet-2859	144	29	values	value	NOUN
admet-2859	144	30	for	for	ADP
admet-2859	144	31	cd	cd	NOUN
admet-2859	144	32	-	-	PUNCT
admet-2859	144	33	none	none	NOUN
admet-2859	144	34	and	and	CCONJ
admet-2859	144	35	cd	cd	NOUN
admet-2859	144	36	-	-	PUNCT
admet-2859	144	37	acceptor	acceptor	NOUN
admet-2859	144	38	in	in	ADP
admet-2859	144	39	table	table	NOUN
admet-2859	144	40	4	4	NUM
admet-2859	144	41	)	)	PUNCT
admet-2859	144	42	,	,	PUNCT
admet-2859	144	43	while	while	SCONJ
admet-2859	144	44	a	a	DET
admet-2859	144	45	significant	significant	ADJ
admet-2859	144	46	difference	difference	NOUN
admet-2859	144	47	is	be	AUX
admet-2859	144	48	seen	see	VERB
admet-2859	144	49	in	in	ADP
admet-2859	144	50	the	the	DET
admet-2859	144	51	case	case	NOUN
admet-2859	144	52	of	of	ADP
admet-2859	144	53	the	the	DET
admet-2859	144	54	lipophilic	lipophilic	ADJ
admet-2859	144	55	membrane	membrane	NOUN
admet-2859	144	56	.	.	PUNCT
admet-2859	145	1	in	in	ADP
admet-2859	145	2	a	a	DET
admet-2859	145	3	similar	similar	ADJ
admet-2859	145	4	situation	situation	NOUN
admet-2859	145	5	,	,	PUNCT
admet-2859	145	6	where	where	SCONJ
admet-2859	145	7	cd	cd	PROPN
admet-2859	145	8	in	in	ADP
admet-2859	145	9	the	the	DET
admet-2859	145	10	donor	donor	NOUN
admet-2859	145	11	compartment	compartment	NOUN
admet-2859	145	12	is	be	AUX
admet-2859	145	13	compared	compare	VERB
admet-2859	145	14	with	with	ADP
admet-2859	145	15	the	the	DET
admet-2859	145	16	scenario	scenario	NOUN
admet-2859	145	17	in	in	ADP
admet-2859	145	18	which	which	PRON
admet-2859	145	19	both	both	DET
admet-2859	145	20	sides	side	NOUN
admet-2859	145	21	contain	contain	VERB
admet-2859	145	22	cd	cd	NOUN
admet-2859	145	23	(	(	PUNCT
admet-2859	145	24	table	table	NOUN
admet-2859	145	25	4	4	NUM
admet-2859	145	26	,	,	PUNCT
admet-2859	145	27	p	p	NOUN
admet-2859	145	28	-	-	PUNCT
admet-2859	145	29	values	value	NOUN
admet-2859	145	30	for	for	ADP
admet-2859	145	31	donor	donor	NOUN
admet-2859	145	32	and	and	CCONJ
admet-2859	145	33	both	both	PRON
admet-2859	145	34	):	):	PUNCT
admet-2859	145	35	in	in	ADP
admet-2859	145	36	the	the	DET
admet-2859	145	37	case	case	NOUN
admet-2859	145	38	of	of	ADP
admet-2859	145	39	the	the	DET
admet-2859	145	40	lipophilic	lipophilic	ADJ
admet-2859	145	41	membrane	membrane	NOUN
admet-2859	145	42	,	,	PUNCT
admet-2859	145	43	the	the	DET
admet-2859	145	44	deviation	deviation	NOUN
admet-2859	145	45	from	from	ADP
admet-2859	145	46	the	the	DET
admet-2859	145	47	parallel	parallel	ADJ
admet-2859	145	48	lines	line	NOUN
admet-2859	145	49	is	be	AUX
admet-2859	145	50	significant	significant	ADJ
admet-2859	145	51	,	,	PUNCT
admet-2859	145	52	but	but	CCONJ
admet-2859	145	53	for	for	ADP
admet-2859	145	54	the	the	DET
admet-2859	145	55	size	size	NOUN
admet-2859	145	56	-	-	PUNCT
admet-2859	145	57	exclusion	exclusion	NOUN
admet-2859	145	58	membranes	membrane	NOUN
admet-2859	145	59	,	,	PUNCT
admet-2859	145	60	it	it	PRON
admet-2859	145	61	is	be	AUX
admet-2859	145	62	not	not	PART
admet-2859	145	63	.	.	PUNCT
admet-2859	146	1	in	in	ADP
admet-2859	146	2	conclusion	conclusion	NOUN
admet-2859	146	3	,	,	PUNCT
admet-2859	146	4	for	for	ADP
admet-2859	146	5	the	the	DET
admet-2859	146	6	lipophilic	lipophilic	ADJ
admet-2859	146	7	membrane	membrane	NOUN
admet-2859	146	8	,	,	PUNCT
admet-2859	146	9	where	where	SCONJ
admet-2859	146	10	the	the	DET
admet-2859	146	11	sink	sink	NOUN
admet-2859	146	12	effect	effect	NOUN
admet-2859	146	13	significantly	significantly	ADV
admet-2859	146	14	influenced	influence	VERB
admet-2859	146	15	permeability	permeability	NOUN
admet-2859	146	16	(	(	PUNCT
admet-2859	146	17	figure	figure	NOUN
admet-2859	146	18	4	4	NUM
admet-2859	146	19	)	)	PUNCT
admet-2859	146	20	,	,	PUNCT
admet-2859	146	21	a	a	DET
admet-2859	146	22	significantly	significantly	ADV
admet-2859	146	23	greater	great	ADJ
admet-2859	146	24	coefficient	coefficient	NOUN
admet-2859	146	25	of	of	ADP
admet-2859	146	26	proportionality	proportionality	NOUN
admet-2859	146	27	(	(	PUNCT
admet-2859	146	28	be	be	AUX
admet-2859	146	29	)	)	PUNCT
admet-2859	146	30	(	(	PUNCT
admet-2859	146	31	slope	slope	NOUN
admet-2859	146	32	of	of	ADP
admet-2859	146	33	the	the	DET
admet-2859	146	34	purple	purple	ADJ
admet-2859	146	35	cd	cd	PROPN
admet-2859	146	36	-	-	PUNCT
admet-2859	146	37	acceptor	acceptor	NOUN
admet-2859	146	38	curve	curve	NOUN
admet-2859	146	39	on	on	ADP
admet-2859	146	40	figure	figure	NOUN
admet-2859	146	41	5	5	NUM
admet-2859	146	42	)	)	PUNCT
admet-2859	146	43	is	be	AUX
admet-2859	146	44	observed	observe	VERB
admet-2859	146	45	compared	compare	VERB
admet-2859	146	46	to	to	ADP
admet-2859	146	47	the	the	DET
admet-2859	146	48	‘	'	PUNCT
admet-2859	146	49	cd	cd	NOUN
admet-2859	146	50	-	-	PUNCT
admet-2859	146	51	none	none	NOUN
admet-2859	146	52	’	'	PUNCT
admet-2859	146	53	buffer	buffer	NOUN
admet-2859	146	54	(	(	PUNCT
admet-2859	146	55	slope	slope	NOUN
admet-2859	146	56	of	of	ADP
admet-2859	146	57	the	the	DET
admet-2859	146	58	red	red	ADJ
admet-2859	146	59	curve	curve	NOUN
admet-2859	146	60	on	on	ADP
admet-2859	146	61	figure	figure	NOUN
admet-2859	146	62	5	5	NUM
admet-2859	146	63	)	)	PUNCT
admet-2859	146	64	.	.	PUNCT
admet-2859	147	1	admet	admet	PROPN
admet-2859	147	2	&	&	CCONJ
admet-2859	147	3	dmpk	dmpk	PROPN
admet-2859	147	4	13(5	13(5	NUM
admet-2859	147	5	)	)	PUNCT
admet-2859	147	6	(	(	PUNCT
admet-2859	147	7	2025	2025	NUM
admet-2859	147	8	)	)	PUNCT
admet-2859	147	9	2859	2859	NUM
admet-2859	147	10	comparison	comparison	NOUN
admet-2859	147	11	of	of	ADP
admet-2859	147	12	lipophilic	lipophilic	ADJ
admet-2859	147	13	and	and	CCONJ
admet-2859	147	14	size	size	NOUN
admet-2859	147	15	-	-	PUNCT
admet-2859	147	16	exclusion	exclusion	NOUN
admet-2859	147	17	membranes	membrane	NOUN
admet-2859	147	18	doi	doi	NOUN
admet-2859	147	19	:	:	PUNCT
admet-2859	147	20	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	NOUN
admet-2859	147	21	9	9	NUM
admet-2859	147	22	figure	figure	NOUN
admet-2859	147	23	5	5	NUM
admet-2859	147	24	.	.	PUNCT
admet-2859	147	25	flux	flux	PROPN
admet-2859	147	26	–	–	PUNCT
admet-2859	147	27	ssr	ssr	ADJ
admet-2859	147	28	curves	curve	NOUN
admet-2859	147	29	in	in	ADP
admet-2859	147	30	ph	ph	ADJ
admet-2859	147	31	10	10	NUM
admet-2859	147	32	buffer	buffer	NOUN
admet-2859	147	33	with	with	ADP
admet-2859	147	34	250	250	NUM
admet-2859	147	35	rpm	rpm	ADJ
admet-2859	147	36	stirring	stirring	NOUN
admet-2859	147	37	rate	rate	NOUN
admet-2859	147	38	for	for	ADP
admet-2859	147	39	lipophilic	lipophilic	ADJ
admet-2859	147	40	membrane	membrane	NOUN
admet-2859	147	41	,	,	PUNCT
admet-2859	147	42	1	1	NUM
admet-2859	147	43	and	and	CCONJ
admet-2859	147	44	6	6	NUM
admet-2859	147	45	kda	kda	NOUN
admet-2859	147	46	sizeexclusion	sizeexclusion	NOUN
admet-2859	147	47	membranes	membrane	NOUN
admet-2859	147	48	.	.	PUNCT
admet-2859	148	1	no	no	DET
admet-2859	148	2	hp	hp	PROPN
admet-2859	148	3	-	-	PUNCT
admet-2859	148	4	β	β	NOUN
admet-2859	148	5	-	-	NOUN
admet-2859	148	6	cd	cd	NOUN
admet-2859	148	7	present	present	NOUN
admet-2859	148	8	on	on	ADP
admet-2859	148	9	either	either	DET
admet-2859	148	10	side	side	NOUN
admet-2859	148	11	of	of	ADP
admet-2859	148	12	the	the	DET
admet-2859	148	13	membrane	membrane	NOUN
admet-2859	148	14	with	with	ADP
admet-2859	148	15	red	red	ADJ
admet-2859	148	16	dotted	dot	VERB
admet-2859	148	17	line	line	NOUN
admet-2859	148	18	called	call	VERB
admet-2859	148	19	‘	'	PUNCT
admet-2859	148	20	cd	cd	NOUN
admet-2859	148	21	-	-	PUNCT
admet-2859	148	22	none	none	NOUN
admet-2859	148	23	’	'	PUNCT
admet-2859	148	24	,	,	PUNCT
admet-2859	148	25	addition	addition	NOUN
admet-2859	148	26	of	of	ADP
admet-2859	148	27	hp	hp	NOUN
admet-2859	148	28	-	-	PUNCT
admet-2859	148	29	β	β	NOUN
admet-2859	148	30	-	-	NOUN
admet-2859	148	31	cd	cd	NOUN
admet-2859	148	32	to	to	PART
admet-2859	148	33	acceptor	acceptor	NOUN
admet-2859	148	34	side	side	NOUN
admet-2859	148	35	with	with	ADP
admet-2859	148	36	purple	purple	ADJ
admet-2859	148	37	dots	dot	NOUN
admet-2859	148	38	called	call	VERB
admet-2859	148	39	‘	'	PUNCT
admet-2859	148	40	cd	cd	NOUN
admet-2859	148	41	-	-	PUNCT
admet-2859	148	42	acceptor	acceptor	NOUN
admet-2859	148	43	’	'	PUNCT
admet-2859	148	44	,	,	PUNCT
admet-2859	148	45	addition	addition	NOUN
admet-2859	148	46	of	of	ADP
admet-2859	148	47	hp	hp	NOUN
admet-2859	148	48	-	-	PUNCT
admet-2859	148	49	β	β	NOUN
admet-2859	148	50	-	-	NOUN
admet-2859	148	51	cd	cd	NOUN
admet-2859	148	52	to	to	PART
admet-2859	148	53	donor	donor	VERB
admet-2859	148	54	side	side	NOUN
admet-2859	148	55	with	with	ADP
admet-2859	148	56	green	green	PROPN
admet-2859	148	57	dashed	dash	VERB
admet-2859	148	58	line	line	NOUN
admet-2859	148	59	called	call	VERB
admet-2859	148	60	‘	'	PUNCT
admet-2859	148	61	cd	cd	NOUN
admet-2859	148	62	-	-	PUNCT
admet-2859	148	63	donor	donor	NOUN
admet-2859	148	64	’	'	PUNCT
admet-2859	148	65	and	and	CCONJ
admet-2859	148	66	addition	addition	NOUN
admet-2859	148	67	of	of	ADP
admet-2859	148	68	hp	hp	NOUN
admet-2859	148	69	-	-	PUNCT
admet-2859	148	70	β	β	NOUN
admet-2859	148	71	-	-	NOUN
admet-2859	148	72	cd	cd	NOUN
admet-2859	148	73	to	to	ADP
admet-2859	148	74	both	both	DET
admet-2859	148	75	sides	side	NOUN
admet-2859	148	76	with	with	ADP
admet-2859	148	77	blue	blue	ADJ
admet-2859	148	78	triangles	triangle	NOUN
admet-2859	148	79	called	call	VERB
admet-2859	148	80	‘	'	PUNCT
admet-2859	148	81	cd	cd	NOUN
admet-2859	148	82	-	-	PUNCT
admet-2859	148	83	both	both	PRON
admet-2859	148	84	’	'	PUNCT
admet-2859	148	85	this	this	PRON
admet-2859	148	86	can	can	AUX
admet-2859	148	87	be	be	AUX
admet-2859	148	88	explained	explain	VERB
admet-2859	148	89	by	by	ADP
admet-2859	148	90	equation	equation	NOUN
admet-2859	148	91	(	(	PUNCT
admet-2859	148	92	3	3	NUM
admet-2859	148	93	):	):	PUNCT
admet-2859	148	94	specifically	specifically	ADV
admet-2859	148	95	,	,	PUNCT
admet-2859	148	96	when	when	SCONJ
admet-2859	148	97	a	a	DET
admet-2859	148	98	solubilizing	solubilize	VERB
admet-2859	148	99	agent	agent	NOUN
admet-2859	148	100	is	be	AUX
admet-2859	148	101	added	add	VERB
admet-2859	148	102	to	to	ADP
admet-2859	148	103	the	the	DET
admet-2859	148	104	acceptor	acceptor	NOUN
admet-2859	148	105	side	side	NOUN
admet-2859	148	106	,	,	PUNCT
admet-2859	148	107	the	the	DET
admet-2859	148	108	solubility	solubility	NOUN
admet-2859	148	109	in	in	ADP
admet-2859	148	110	the	the	DET
admet-2859	148	111	acceptor	acceptor	NOUN
admet-2859	148	112	compartment	compartment	NOUN
admet-2859	148	113	increases	increase	NOUN
admet-2859	148	114	ca	ca	NOUN
admet-2859	148	115	*	*	PUNCT
admet-2859	148	116	,	,	PUNCT
admet-2859	148	117	which	which	PRON
admet-2859	148	118	is	be	AUX
admet-2859	148	119	factored	factor	VERB
admet-2859	148	120	into	into	ADP
admet-2859	148	121	the	the	DET
admet-2859	148	122	calculation	calculation	NOUN
admet-2859	148	123	of	of	ADP
admet-2859	148	124	the	the	DET
admet-2859	148	125	difference	difference	NOUN
admet-2859	148	126	in	in	ADP
admet-2859	148	127	supersaturation	supersaturation	NOUN
admet-2859	148	128	ratio	ratio	NOUN
admet-2859	148	129	(	(	PUNCT
admet-2859	148	130	x	x	NOUN
admet-2859	148	131	-	-	NOUN
admet-2859	148	132	axis	axis	NOUN
admet-2859	148	133	on	on	ADP
admet-2859	148	134	figure	figure	NOUN
admet-2859	148	135	5	5	NUM
admet-2859	148	136	)	)	PUNCT
admet-2859	148	137	.	.	PUNCT
admet-2859	149	1	also	also	ADV
admet-2859	149	2	,	,	PUNCT
admet-2859	149	3	the	the	DET
admet-2859	149	4	solubility	solubility	NOUN
admet-2859	149	5	of	of	ADP
admet-2859	149	6	api	api	NOUN
admet-2859	149	7	in	in	ADP
admet-2859	149	8	the	the	DET
admet-2859	149	9	uwl	uwl	NOUN
admet-2859	149	10	cuwl	cuwl	NOUN
admet-2859	149	11	*	*	PUNCT
admet-2859	149	12	is	be	AUX
admet-2859	149	13	elevated	elevate	VERB
admet-2859	149	14	(	(	PUNCT
admet-2859	149	15	3	3	NUM
admet-2859	149	16	times	time	NOUN
admet-2859	149	17	higher	high	ADJ
admet-2859	149	18	)	)	PUNCT
admet-2859	149	19	compared	compare	VERB
admet-2859	149	20	to	to	ADP
admet-2859	149	21	the	the	DET
admet-2859	149	22	‘	'	PUNCT
admet-2859	149	23	cd	cd	NOUN
admet-2859	149	24	-	-	PUNCT
admet-2859	149	25	none	none	NOUN
admet-2859	149	26	’	'	PUNCT
admet-2859	149	27	buffer	buffer	NOUN
admet-2859	149	28	,	,	PUNCT
admet-2859	149	29	due	due	ADP
admet-2859	149	30	to	to	ADP
admet-2859	149	31	the	the	DET
admet-2859	149	32	presence	presence	NOUN
admet-2859	149	33	of	of	ADP
admet-2859	149	34	the	the	DET
admet-2859	149	35	cds	cd	NOUN
admet-2859	149	36	in	in	ADP
admet-2859	149	37	the	the	DET
admet-2859	149	38	aqueous	aqueous	ADJ
admet-2859	149	39	boundary	boundary	ADJ
admet-2859	149	40	layer	layer	NOUN
admet-2859	149	41	of	of	ADP
admet-2859	149	42	the	the	DET
admet-2859	149	43	acceptor	acceptor	NOUN
admet-2859	149	44	side	side	NOUN
admet-2859	149	45	.	.	PUNCT
admet-2859	150	1	when	when	SCONJ
admet-2859	150	2	the	the	DET
admet-2859	150	3	api	api	NOUN
admet-2859	150	4	is	be	AUX
admet-2859	150	5	diffusing	diffuse	VERB
admet-2859	150	6	through	through	ADP
admet-2859	150	7	the	the	DET
admet-2859	150	8	uwl	uwl	NOUN
admet-2859	150	9	as	as	ADP
admet-2859	150	10	a	a	DET
admet-2859	150	11	cd	cd	NOUN
admet-2859	150	12	complex	complex	NOUN
admet-2859	150	13	,	,	PUNCT
admet-2859	150	14	the	the	DET
admet-2859	150	15	molecular	molecular	ADJ
admet-2859	150	16	weight	weight	NOUN
admet-2859	150	17	is	be	AUX
admet-2859	150	18	increased	increase	VERB
admet-2859	150	19	,	,	PUNCT
admet-2859	150	20	resulting	result	VERB
admet-2859	150	21	in	in	ADP
admet-2859	150	22	slower	slow	ADJ
admet-2859	150	23	diffusion	diffusion	NOUN
admet-2859	150	24	and	and	CCONJ
admet-2859	150	25	a	a	DET
admet-2859	150	26	reduction	reduction	NOUN
admet-2859	150	27	in	in	ADP
admet-2859	150	28	puwl	puwl	ADJ
admet-2859	150	29	value	value	NOUN
admet-2859	150	30	.	.	PUNCT
admet-2859	151	1	however	however	ADV
admet-2859	151	2	,	,	PUNCT
admet-2859	151	3	the	the	DET
admet-2859	151	4	cd	cd	PROPN
admet-2859	151	5	complex	complex	NOUN
admet-2859	151	6	is	be	AUX
admet-2859	151	7	not	not	PART
admet-2859	151	8	only	only	ADV
admet-2859	151	9	bigger	big	ADJ
admet-2859	151	10	in	in	ADP
admet-2859	151	11	size	size	NOUN
admet-2859	151	12	,	,	PUNCT
admet-2859	151	13	but	but	CCONJ
admet-2859	151	14	also	also	ADV
admet-2859	151	15	much	much	ADV
admet-2859	151	16	more	more	ADV
admet-2859	151	17	hydrophilic	hydrophilic	ADJ
admet-2859	151	18	than	than	ADP
admet-2859	151	19	the	the	DET
admet-2859	151	20	api	api	NOUN
admet-2859	151	21	;	;	PUNCT
admet-2859	151	22	therefore	therefore	ADV
admet-2859	151	23	,	,	PUNCT
admet-2859	151	24	one	one	NUM
admet-2859	151	25	of	of	ADP
admet-2859	151	26	the	the	DET
admet-2859	151	27	main	main	ADJ
admet-2859	151	28	assumptions	assumption	NOUN
admet-2859	151	29	of	of	ADP
admet-2859	151	30	the	the	DET
admet-2859	151	31	calculations	calculation	NOUN
admet-2859	151	32	[	[	X
admet-2859	151	33	1,46	1,46	X
admet-2859	151	34	]	]	X
admet-2859	151	35	is	be	AUX
admet-2859	151	36	that	that	SCONJ
admet-2859	151	37	only	only	ADV
admet-2859	151	38	the	the	DET
admet-2859	151	39	free	free	ADJ
admet-2859	151	40	drug	drug	NOUN
admet-2859	151	41	encounters	encounter	VERB
admet-2859	151	42	a	a	DET
admet-2859	151	43	significant	significant	ADJ
admet-2859	151	44	unstirred	unstirred	ADJ
admet-2859	151	45	water	water	NOUN
admet-2859	151	46	layer	layer	NOUN
admet-2859	151	47	thickness	thickness	NOUN
admet-2859	151	48	,	,	PUNCT
admet-2859	151	49	but	but	CCONJ
admet-2859	151	50	the	the	DET
admet-2859	151	51	unstirred	unstirred	ADJ
admet-2859	151	52	water	water	NOUN
admet-2859	151	53	layer	layer	NOUN
admet-2859	151	54	thickness	thickness	NOUN
admet-2859	151	55	is	be	AUX
admet-2859	151	56	negligible	negligible	ADJ
admet-2859	151	57	for	for	ADP
admet-2859	151	58	the	the	DET
admet-2859	151	59	car	car	NOUN
admet-2859	151	60	/	/	SYM
admet-2859	151	61	hp	hp	PROPN
admet-2859	151	62	-	-	PUNCT
admet-2859	151	63	β	β	NOUN
admet-2859	151	64	-	-	ADJ
admet-2859	151	65	cd	cd	ADJ
admet-2859	151	66	complex	complex	NOUN
admet-2859	151	67	.	.	PUNCT
admet-2859	152	1	this	this	DET
admet-2859	152	2	assumption	assumption	NOUN
admet-2859	152	3	leads	lead	VERB
admet-2859	152	4	to	to	ADP
admet-2859	152	5	higher	high	ADJ
admet-2859	152	6	puwl	puwl	ADJ
admet-2859	152	7	values	value	NOUN
admet-2859	152	8	in	in	ADP
admet-2859	152	9	the	the	DET
admet-2859	152	10	presence	presence	NOUN
admet-2859	152	11	of	of	ADP
admet-2859	152	12	cd	cd	PROPN
admet-2859	152	13	and	and	CCONJ
admet-2859	152	14	also	also	ADV
admet-2859	152	15	causes	cause	VERB
admet-2859	152	16	the	the	DET
admet-2859	152	17	apparent	apparent	ADJ
admet-2859	152	18	duwl	duwl	NOUN
admet-2859	152	19	value	value	NOUN
admet-2859	152	20	to	to	PART
admet-2859	152	21	decrease	decrease	VERB
admet-2859	152	22	(	(	PUNCT
admet-2859	152	23	table	table	NOUN
admet-2859	152	24	3	3	NUM
admet-2859	152	25	)	)	PUNCT
admet-2859	152	26	.	.	PUNCT
admet-2859	153	1	these	these	PRON
admet-2859	153	2	cause	cause	VERB
admet-2859	153	3	an	an	DET
admet-2859	153	4	increase	increase	NOUN
admet-2859	153	5	in	in	ADP
admet-2859	153	6	the	the	DET
admet-2859	153	7	numerator	numerator	NOUN
admet-2859	153	8	of	of	ADP
admet-2859	153	9	the	the	DET
admet-2859	153	10	buwl	buwl	ADJ
admet-2859	153	11	value	value	NOUN
admet-2859	153	12	(	(	PUNCT
admet-2859	153	13	equation	equation	NOUN
admet-2859	153	14	(	(	PUNCT
admet-2859	153	15	3	3	NUM
admet-2859	153	16	)	)	PUNCT
admet-2859	153	17	)	)	PUNCT
admet-2859	153	18	.	.	PUNCT
admet-2859	154	1	in	in	ADP
admet-2859	154	2	literature	literature	NOUN
admet-2859	154	3	,	,	PUNCT
admet-2859	154	4	the	the	DET
admet-2859	154	5	addition	addition	NOUN
admet-2859	154	6	of	of	ADP
admet-2859	154	7	cd	cd	PROPN
admet-2859	154	8	has	have	AUX
admet-2859	154	9	been	be	AUX
admet-2859	154	10	previously	previously	ADV
admet-2859	154	11	noted	note	VERB
admet-2859	154	12	to	to	PART
admet-2859	154	13	cause	cause	VERB
admet-2859	154	14	a	a	DET
admet-2859	154	15	reduction	reduction	NOUN
admet-2859	154	16	of	of	ADP
admet-2859	154	17	the	the	DET
admet-2859	154	18	apparent	apparent	ADJ
admet-2859	154	19	uwl	uwl	NOUN
admet-2859	154	20	thickness	thickness	NOUN
admet-2859	154	21	,	,	PUNCT
admet-2859	154	22	which	which	PRON
admet-2859	154	23	may	may	AUX
admet-2859	154	24	also	also	ADV
admet-2859	154	25	be	be	AUX
admet-2859	154	26	interpreted	interpret	VERB
admet-2859	154	27	as	as	ADP
admet-2859	154	28	an	an	DET
admet-2859	154	29	elevation	elevation	NOUN
admet-2859	154	30	of	of	ADP
admet-2859	154	31	the	the	DET
admet-2859	154	32	proportionality	proportionality	NOUN
admet-2859	154	33	coefficient	coefficient	NOUN
admet-2859	154	34	(	(	PUNCT
admet-2859	154	35	buwl	buwl	NOUN
admet-2859	154	36	)	)	PUNCT
admet-2859	155	1	[	[	X
admet-2859	155	2	36	36	NUM
admet-2859	155	3	]	]	PUNCT
admet-2859	155	4	.	.	PUNCT
admet-2859	156	1	these	these	DET
admet-2859	156	2	effects	effect	NOUN
admet-2859	156	3	can	can	AUX
admet-2859	156	4	be	be	AUX
admet-2859	156	5	seen	see	VERB
admet-2859	156	6	in	in	ADP
admet-2859	156	7	figure	figure	NOUN
admet-2859	156	8	5	5	NUM
admet-2859	156	9	:	:	PUNCT
admet-2859	156	10	the	the	DET
admet-2859	156	11	purple	purple	ADJ
admet-2859	156	12	curve	curve	NOUN
admet-2859	156	13	becomes	become	VERB
admet-2859	156	14	steeper	steep	ADJ
admet-2859	156	15	than	than	ADP
admet-2859	156	16	the	the	DET
admet-2859	156	17	red	red	ADJ
admet-2859	156	18	curve	curve	NOUN
admet-2859	156	19	belonging	belong	VERB
admet-2859	156	20	to	to	ADP
admet-2859	156	21	the	the	DET
admet-2859	156	22	cd	cd	PROPN
admet-2859	156	23	-	-	PUNCT
admet-2859	156	24	none	none	NOUN
admet-2859	156	25	buffer	buffer	NOUN
admet-2859	156	26	.	.	PUNCT
admet-2859	157	1	in	in	ADP
admet-2859	157	2	a	a	DET
admet-2859	157	3	similar	similar	ADJ
admet-2859	157	4	situation	situation	NOUN
admet-2859	157	5	,	,	PUNCT
admet-2859	157	6	when	when	SCONJ
admet-2859	157	7	cd	cd	PROPN
admet-2859	157	8	is	be	AUX
admet-2859	157	9	present	present	ADJ
admet-2859	157	10	in	in	ADP
admet-2859	157	11	the	the	DET
admet-2859	157	12	donor	donor	NOUN
admet-2859	157	13	compartment	compartment	NOUN
admet-2859	157	14	versus	versus	ADP
admet-2859	157	15	a	a	DET
admet-2859	157	16	scenario	scenario	NOUN
admet-2859	157	17	where	where	SCONJ
admet-2859	157	18	both	both	DET
admet-2859	157	19	sides	side	NOUN
admet-2859	157	20	contain	contain	VERB
admet-2859	157	21	cd	cd	PROPN
admet-2859	157	22	,	,	PUNCT
admet-2859	157	23	the	the	DET
admet-2859	157	24	same	same	ADJ
admet-2859	157	25	explanation	explanation	NOUN
admet-2859	157	26	can	can	AUX
admet-2859	157	27	be	be	AUX
admet-2859	157	28	applied	apply	VERB
admet-2859	157	29	using	use	VERB
admet-2859	157	30	equation	equation	NOUN
admet-2859	157	31	(	(	PUNCT
admet-2859	157	32	3	3	NUM
admet-2859	157	33	)	)	PUNCT
admet-2859	157	34	.	.	PUNCT
admet-2859	158	1	lipophilic	lipophilic	ADJ
admet-2859	158	2	and	and	CCONJ
admet-2859	158	3	size	size	NOUN
admet-2859	158	4	-	-	PUNCT
admet-2859	158	5	exclusion	exclusion	NOUN
admet-2859	158	6	membranes	membrane	NOUN
admet-2859	158	7	are	be	AUX
admet-2859	158	8	mechanistically	mechanistically	ADV
admet-2859	158	9	different	different	ADJ
admet-2859	158	10	:	:	PUNCT
admet-2859	158	11	in	in	ADP
admet-2859	158	12	the	the	DET
admet-2859	158	13	case	case	NOUN
admet-2859	158	14	of	of	ADP
admet-2859	158	15	lipophilic	lipophilic	ADJ
admet-2859	158	16	membranes	membrane	NOUN
admet-2859	158	17	,	,	PUNCT
admet-2859	158	18	only	only	ADV
admet-2859	158	19	the	the	DET
admet-2859	158	20	drug	drug	NOUN
admet-2859	158	21	can	can	AUX
admet-2859	158	22	permeate	permeate	VERB
admet-2859	158	23	the	the	DET
admet-2859	158	24	membrane	membrane	NOUN
admet-2859	158	25	,	,	PUNCT
admet-2859	158	26	while	while	SCONJ
admet-2859	158	27	in	in	ADP
admet-2859	158	28	the	the	DET
admet-2859	158	29	case	case	NOUN
admet-2859	158	30	of	of	ADP
admet-2859	158	31	size	size	NOUN
admet-2859	158	32	-	-	PUNCT
admet-2859	158	33	exclusion	exclusion	NOUN
admet-2859	158	34	membranes	membrane	NOUN
admet-2859	158	35	,	,	PUNCT
admet-2859	158	36	also	also	ADV
admet-2859	158	37	the	the	DET
admet-2859	158	38	cd	cd	PROPN
admet-2859	158	39	and	and	CCONJ
admet-2859	158	40	the	the	DET
admet-2859	158	41	drug	drug	NOUN
admet-2859	158	42	-	-	PUNCT
admet-2859	158	43	cd	cd	NOUN
admet-2859	158	44	complex	complex	NOUN
admet-2859	158	45	are	be	AUX
admet-2859	158	46	able	able	ADJ
admet-2859	158	47	to	to	PART
admet-2859	158	48	go	go	VERB
admet-2859	158	49	through	through	ADV
admet-2859	158	50	.	.	PUNCT
admet-2859	159	1	a	a	DET
admet-2859	159	2	prior	prior	ADJ
admet-2859	159	3	study	study	NOUN
admet-2859	159	4	[	[	X
admet-2859	159	5	1	1	X
admet-2859	159	6	]	]	PUNCT
admet-2859	159	7	demonstrated	demonstrate	VERB
admet-2859	159	8	that	that	SCONJ
admet-2859	159	9	the	the	DET
admet-2859	159	10	transport	transport	NOUN
admet-2859	159	11	of	of	ADP
admet-2859	159	12	the	the	DET
admet-2859	159	13	hp	hp	PROPN
admet-2859	159	14	-	-	PUNCT
admet-2859	159	15	β	β	NOUN
admet-2859	159	16	-	-	NOUN
admet-2859	159	17	cd	cd	NOUN
admet-2859	159	18	across	across	ADP
admet-2859	159	19	a	a	DET
admet-2859	159	20	1kda	1kda	NUM
admet-2859	159	21	mwco	mwco	NOUN
admet-2859	159	22	membrane	membrane	NOUN
admet-2859	159	23	is	be	AUX
admet-2859	159	24	quite	quite	ADV
admet-2859	159	25	slow	slow	ADJ
admet-2859	159	26	,	,	PUNCT
admet-2859	159	27	becoming	become	VERB
admet-2859	159	28	detectable	detectable	ADJ
admet-2859	159	29	on	on	ADP
admet-2859	159	30	the	the	DET
admet-2859	159	31	opposite	opposite	ADJ
admet-2859	159	32	side	side	NOUN
admet-2859	159	33	after	after	ADP
admet-2859	159	34	4	4	NUM
admet-2859	159	35	hours	hour	NOUN
admet-2859	159	36	.	.	PUNCT
admet-2859	160	1	in	in	ADP
admet-2859	160	2	contrast	contrast	NOUN
admet-2859	160	3	,	,	PUNCT
admet-2859	160	4	the	the	DET
admet-2859	160	5	transport	transport	NOUN
admet-2859	160	6	across	across	ADP
admet-2859	160	7	a	a	DET
admet-2859	160	8	6	6	NUM
admet-2859	160	9	kda	kda	NOUN
admet-2859	160	10	mwco	mwco	NOUN
admet-2859	160	11	membrane	membrane	NOUN
admet-2859	160	12	was	be	AUX
admet-2859	160	13	found	find	VERB
admet-2859	160	14	to	to	PART
admet-2859	160	15	be	be	AUX
admet-2859	160	16	substantially	substantially	ADV
admet-2859	160	17	faster	fast	ADV
admet-2859	160	18	,	,	PUNCT
admet-2859	160	19	reaching	reach	VERB
admet-2859	160	20	the	the	DET
admet-2859	160	21	detection	detection	NOUN
admet-2859	160	22	threshold	threshold	NOUN
admet-2859	160	23	in	in	ADP
admet-2859	160	24	merely	merely	ADV
admet-2859	160	25	2	2	NUM
admet-2859	160	26	hours	hour	NOUN
admet-2859	160	27	.	.	PUNCT
admet-2859	161	1	when	when	SCONJ
admet-2859	161	2	the	the	DET
admet-2859	161	3	cd	cd	PROPN
admet-2859	161	4	is	be	AUX
admet-2859	161	5	placed	place	VERB
admet-2859	161	6	on	on	ADP
admet-2859	161	7	the	the	DET
admet-2859	161	8	acceptor	acceptor	NOUN
admet-2859	161	9	side	side	NOUN
admet-2859	161	10	to	to	PART
admet-2859	161	11	create	create	VERB
admet-2859	161	12	a	a	DET
admet-2859	161	13	sink	sink	NOUN
admet-2859	161	14	condition	condition	NOUN
admet-2859	161	15	and	and	CCONJ
admet-2859	161	16	a	a	DET
admet-2859	161	17	size	size	NOUN
admet-2859	161	18	-	-	PUNCT
admet-2859	161	19	exclusion	exclusion	NOUN
admet-2859	161	20	membrane	membrane	NOUN
admet-2859	161	21	is	be	AUX
admet-2859	161	22	used	use	VERB
admet-2859	161	23	,	,	PUNCT
admet-2859	161	24	the	the	DET
admet-2859	161	25	cd	cd	PROPN
admet-2859	161	26	can	can	AUX
admet-2859	161	27	cross	cross	VERB
admet-2859	161	28	the	the	DET
admet-2859	161	29	membrane	membrane	NOUN
admet-2859	161	30	and	and	CCONJ
admet-2859	161	31	appear	appear	VERB
admet-2859	161	32	on	on	ADP
admet-2859	161	33	the	the	DET
admet-2859	161	34	donor	donor	NOUN
admet-2859	161	35	side	side	NOUN
admet-2859	161	36	,	,	PUNCT
admet-2859	161	37	while	while	SCONJ
admet-2859	161	38	the	the	DET
admet-2859	161	39	api	api	NOUN
admet-2859	161	40	moves	move	VERB
admet-2859	161	41	in	in	ADP
admet-2859	161	42	the	the	DET
admet-2859	161	43	opposite	opposite	ADJ
admet-2859	161	44	direction	direction	NOUN
admet-2859	161	45	.	.	PUNCT
admet-2859	162	1	figure	figure	NOUN
admet-2859	162	2	5	5	NUM
admet-2859	162	3	,	,	PUNCT
admet-2859	162	4	along	along	ADP
admet-2859	162	5	with	with	ADP
admet-2859	162	6	the	the	DET
admet-2859	162	7	results	result	NOUN
admet-2859	162	8	of	of	ADP
admet-2859	162	9	table	table	NOUN
admet-2859	162	10	4	4	NUM
admet-2859	162	11	,	,	PUNCT
admet-2859	162	12	indicates	indicate	VERB
admet-2859	162	13	that	that	SCONJ
admet-2859	162	14	there	there	PRON
admet-2859	162	15	is	be	VERB
admet-2859	162	16	no	no	DET
admet-2859	162	17	significant	significant	ADJ
admet-2859	162	18	difference	difference	NOUN
admet-2859	162	19	in	in	ADP
admet-2859	162	20	the	the	DET
admet-2859	162	21	slopes	slope	NOUN
admet-2859	162	22	of	of	ADP
admet-2859	162	23	the	the	DET
admet-2859	162	24	cd	cd	PROPN
admet-2859	162	25	-	-	PUNCT
admet-2859	162	26	none	none	NOUN
admet-2859	162	27	buffer	buffer	NOUN
admet-2859	162	28	(	(	PUNCT
admet-2859	162	29	red	red	ADJ
admet-2859	162	30	)	)	PUNCT
admet-2859	162	31	and	and	CCONJ
admet-2859	162	32	cd	cd	PROPN
admet-2859	162	33	placed	place	VERB
admet-2859	162	34	on	on	ADP
admet-2859	162	35	the	the	DET
admet-2859	162	36	acceptor	acceptor	NOUN
admet-2859	162	37	side	side	NOUN
admet-2859	162	38	(	(	PUNCT
admet-2859	162	39	purple	purple	ADJ
admet-2859	162	40	)	)	PUNCT
admet-2859	162	41	.	.	PUNCT
admet-2859	163	1	similarly	similarly	ADV
admet-2859	163	2	,	,	PUNCT
admet-2859	163	3	the	the	DET
admet-2859	163	4	cd	cd	PROPN
admet-2859	163	5	on	on	ADP
admet-2859	163	6	the	the	DET
admet-2859	163	7	donor	donor	NOUN
admet-2859	163	8	side	side	NOUN
admet-2859	163	9	(	(	PUNCT
admet-2859	163	10	green	green	NOUN
admet-2859	163	11	)	)	PUNCT
admet-2859	163	12	and	and	CCONJ
admet-2859	163	13	the	the	DET
admet-2859	163	14	cd	cd	PROPN
admet-2859	163	15	on	on	ADP
admet-2859	163	16	both	both	DET
admet-2859	163	17	sides	side	NOUN
admet-2859	163	18	(	(	PUNCT
admet-2859	163	19	blue	blue	ADJ
admet-2859	163	20	)	)	PUNCT
admet-2859	163	21	also	also	ADV
admet-2859	163	22	exhibit	exhibit	VERB
admet-2859	163	23	perfectly	perfectly	ADV
admet-2859	163	24	parallel	parallel	ADJ
admet-2859	163	25	lines	line	NOUN
admet-2859	163	26	.	.	PUNCT
admet-2859	164	1	these	these	DET
admet-2859	164	2	results	result	NOUN
admet-2859	164	3	show	show	VERB
admet-2859	164	4	that	that	SCONJ
admet-2859	164	5	when	when	SCONJ
admet-2859	164	6	the	the	DET
admet-2859	164	7	solid	solid	ADJ
admet-2859	164	8	membrane	membrane	NOUN
admet-2859	164	9	dividing	divide	VERB
admet-2859	164	10	the	the	DET
admet-2859	164	11	two	two	NUM
admet-2859	164	12	aqueous	aqueous	ADJ
admet-2859	164	13	boundary	boundary	ADJ
admet-2859	164	14	layers	layer	NOUN
admet-2859	164	15	becomes	become	VERB
admet-2859	164	16	permeable	permeable	ADJ
admet-2859	164	17	to	to	ADP
admet-2859	164	18	the	the	DET
admet-2859	164	19	cd	cd	PROPN
admet-2859	164	20	,	,	PUNCT
admet-2859	164	21	the	the	DET
admet-2859	164	22	sink	sink	NOUN
admet-2859	164	23	effect	effect	NOUN
admet-2859	164	24	shown	show	VERB
admet-2859	164	25	with	with	ADP
admet-2859	164	26	the	the	DET
admet-2859	164	27	lipophilic	lipophilic	ADJ
admet-2859	164	28	membrane	membrane	NOUN
admet-2859	164	29	reduces	reduce	NOUN
admet-2859	164	30	,	,	PUNCT
admet-2859	164	31	and	and	CCONJ
admet-2859	164	32	no	no	DET
admet-2859	164	33	significant	significant	ADJ
admet-2859	164	34	deviation	deviation	NOUN
admet-2859	164	35	is	be	AUX
admet-2859	164	36	evident	evident	ADJ
admet-2859	164	37	in	in	ADP
admet-2859	164	38	the	the	DET
admet-2859	164	39	proportionality	proportionality	NOUN
admet-2859	164	40	coefficients	coefficient	NOUN
admet-2859	164	41	.	.	PUNCT
admet-2859	165	1	f	f	X
admet-2859	165	2	lu	lu	PROPN
admet-2859	165	3	x	x	NOUN
admet-2859	165	4	,	,	PUNCT
admet-2859	165	5			NOUN
admet-2859	165	6	g	g	NOUN
admet-2859	165	7	m	m	NOUN
admet-2859	165	8	in	in	ADP
admet-2859	165	9	-1	-1	PROPN
admet-2859	166	1	c	c	NOUN
admet-2859	166	2	m	m	VERB
admet-2859	167	1	-2	-2	INTJ
admet-2859	167	2	f	f	X
admet-2859	167	3	lu	lu	PROPN
admet-2859	167	4	x	x	NOUN
admet-2859	167	5	,	,	PUNCT
admet-2859	167	6			NOUN
admet-2859	167	7	g	g	NOUN
admet-2859	167	8	m	m	NOUN
admet-2859	167	9	in	in	ADP
admet-2859	167	10	-1	-1	PROPN
admet-2859	168	1	c	c	NOUN
admet-2859	168	2	m	m	VERB
admet-2859	169	1	-2	-2	INTJ
admet-2859	169	2	f	f	X
admet-2859	169	3	lu	lu	PROPN
admet-2859	169	4	x	x	NOUN
admet-2859	169	5	,	,	PUNCT
admet-2859	169	6			NOUN
admet-2859	169	7	g	g	NOUN
admet-2859	169	8	m	m	NOUN
admet-2859	169	9	in	in	ADP
admet-2859	169	10	-1	-1	PROPN
admet-2859	170	1	c	c	NOUN
admet-2859	170	2	m	m	VERB
admet-2859	171	1	-2	-2	NOUN
admet-2859	171	2	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	PROPN
admet-2859	172	1	p.	p.	NOUN
admet-2859	172	2	tőzsér	tőzsér	PROPN
admet-2859	172	3	et	et	PROPN
admet-2859	172	4	al	al	PROPN
admet-2859	172	5	.	.	PROPN
admet-2859	172	6	admet	admet	PROPN
admet-2859	172	7	&	&	CCONJ
admet-2859	172	8	dmpk	dmpk	PROPN
admet-2859	172	9	13(5	13(5	NUM
admet-2859	172	10	)	)	PUNCT
admet-2859	172	11	(	(	PUNCT
admet-2859	172	12	2025	2025	NUM
admet-2859	172	13	)	)	PUNCT
admet-2859	172	14	2859	2859	NUM
admet-2859	172	15	10	10	NUM
admet-2859	172	16	table	table	NOUN
admet-2859	172	17	4	4	NUM
admet-2859	172	18	.	.	PUNCT
admet-2859	172	19	homogeneity	homogeneity	NOUN
admet-2859	172	20	of	of	ADP
admet-2859	172	21	slopes	slope	NOUN
admet-2859	172	22	test	test	NOUN
admet-2859	172	23	results	result	NOUN
admet-2859	172	24	for	for	ADP
admet-2859	172	25	flux	flux	NOUN
admet-2859	172	26	-	-	PUNCT
admet-2859	172	27	ssr	ssr	ADJ
admet-2859	172	28	curves	curve	NOUN
admet-2859	172	29	in	in	ADP
admet-2859	172	30	ph	ph	ADJ
admet-2859	172	31	10	10	NUM
admet-2859	172	32	buffer	buffer	NOUN
admet-2859	172	33	with	with	ADP
admet-2859	172	34	250	250	NUM
admet-2859	172	35	rpm	rpm	ADJ
admet-2859	172	36	stirring	stirring	NOUN
admet-2859	172	37	rate	rate	NOUN
admet-2859	172	38	for	for	ADP
admet-2859	172	39	lipophilic	lipophilic	ADJ
admet-2859	172	40	membrane	membrane	NOUN
admet-2859	172	41	,	,	PUNCT
admet-2859	172	42	1	1	NUM
admet-2859	172	43	kd	kd	NOUN
admet-2859	172	44	and	and	CCONJ
admet-2859	172	45	6	6	NUM
admet-2859	172	46	kda	kda	NOUN
admet-2859	172	47	size	size	NOUN
admet-2859	172	48	-	-	PUNCT
admet-2859	172	49	exclusion	exclusion	NOUN
admet-2859	172	50	membranes	membrane	NOUN
admet-2859	172	51	p	p	NOUN
admet-2859	172	52	-	-	PUNCT
admet-2859	172	53	value	value	NOUN
admet-2859	172	54	for	for	ADP
admet-2859	172	55	cd	cd	NOUN
admet-2859	172	56	-	-	PUNCT
admet-2859	172	57	none	none	NOUN
admet-2859	172	58	and	and	CCONJ
admet-2859	172	59	cd	cd	NOUN
admet-2859	172	60	-	-	PUNCT
admet-2859	172	61	acceptor	acceptor	NOUN
admet-2859	172	62	p	p	NOUN
admet-2859	172	63	-	-	PUNCT
admet-2859	172	64	value	value	NOUN
admet-2859	172	65	for	for	ADP
admet-2859	172	66	cd	cd	NOUN
admet-2859	172	67	-	-	PUNCT
admet-2859	172	68	donor	donor	NOUN
admet-2859	172	69	and	and	CCONJ
admet-2859	172	70	cd	cd	PROPN
admet-2859	172	71	-	-	PUNCT
admet-2859	172	72	both	both	PRON
admet-2859	172	73	p	p	NOUN
admet-2859	172	74	-	-	PUNCT
admet-2859	172	75	value	value	NOUN
admet-2859	172	76	for	for	ADP
admet-2859	172	77	cd	cd	NOUN
admet-2859	172	78	-	-	PUNCT
admet-2859	172	79	acceptor	acceptor	NOUN
admet-2859	172	80	and	and	CCONJ
admet-2859	172	81	cd	cd	PROPN
admet-2859	172	82	-	-	PUNCT
admet-2859	172	83	both	both	CCONJ
admet-2859	172	84	lipophilic	lipophilic	ADJ
admet-2859	172	85	0.000787	0.000787	NUM
admet-2859	172	86	0.001689	0.001689	NUM
admet-2859	172	87	0.819284	0.819284	NUM
admet-2859	172	88	1	1	NUM
admet-2859	172	89	kda	kda	NOUN
admet-2859	172	90	0.923485	0.923485	NUM
admet-2859	172	91	0.853885	0.853885	NUM
admet-2859	172	92	0.155029	0.155029	NUM
admet-2859	172	93	6	6	NUM
admet-2859	172	94	kda	kda	NOUN
admet-2859	172	95	0.133241	0.133241	NUM
admet-2859	172	96	0.129204	0.129204	NUM
admet-2859	172	97	0.735795	0.735795	NUM
admet-2859	172	98	in	in	ADP
admet-2859	172	99	drug	drug	NOUN
admet-2859	172	100	formulation	formulation	NOUN
admet-2859	172	101	testing	testing	NOUN
admet-2859	172	102	,	,	PUNCT
admet-2859	172	103	the	the	DET
admet-2859	172	104	most	most	ADV
admet-2859	172	105	realistic	realistic	ADJ
admet-2859	172	106	scenario	scenario	NOUN
admet-2859	172	107	occurs	occur	VERB
admet-2859	172	108	when	when	SCONJ
admet-2859	172	109	the	the	DET
admet-2859	172	110	formulation	formulation	NOUN
admet-2859	172	111	releases	release	VERB
admet-2859	172	112	solubilizing	solubilize	VERB
admet-2859	172	113	agents	agent	NOUN
admet-2859	172	114	in	in	ADP
admet-2859	172	115	the	the	DET
admet-2859	172	116	donor	donor	NOUN
admet-2859	172	117	compartment	compartment	NOUN
admet-2859	172	118	,	,	PUNCT
admet-2859	172	119	while	while	SCONJ
admet-2859	172	120	surfactants	surfactant	NOUN
admet-2859	172	121	or	or	CCONJ
admet-2859	172	122	cds	cd	NOUN
admet-2859	172	123	are	be	AUX
admet-2859	172	124	employed	employ	VERB
admet-2859	172	125	in	in	ADP
admet-2859	172	126	the	the	DET
admet-2859	172	127	acceptor	acceptor	NOUN
admet-2859	172	128	compartment	compartment	NOUN
admet-2859	172	129	to	to	PART
admet-2859	172	130	establish	establish	VERB
admet-2859	172	131	sink	sink	NOUN
admet-2859	172	132	conditions	condition	NOUN
admet-2859	172	133	.	.	PUNCT
admet-2859	173	1	therefore	therefore	ADV
admet-2859	173	2	,	,	PUNCT
admet-2859	173	3	the	the	DET
admet-2859	173	4	effect	effect	NOUN
admet-2859	173	5	of	of	ADP
admet-2859	173	6	placing	place	VERB
admet-2859	173	7	a	a	DET
admet-2859	173	8	cd	cd	NOUN
admet-2859	173	9	on	on	ADP
admet-2859	173	10	the	the	DET
admet-2859	173	11	donor	donor	NOUN
admet-2859	173	12	side	side	NOUN
admet-2859	173	13	while	while	SCONJ
admet-2859	173	14	already	already	ADV
admet-2859	173	15	having	have	VERB
admet-2859	173	16	a	a	DET
admet-2859	173	17	cd	cd	NOUN
admet-2859	173	18	on	on	ADP
admet-2859	173	19	the	the	DET
admet-2859	173	20	acceptor	acceptor	NOUN
admet-2859	173	21	side	side	NOUN
admet-2859	173	22	was	be	AUX
admet-2859	173	23	evaluated	evaluate	VERB
admet-2859	173	24	in	in	ADP
admet-2859	173	25	figure	figure	NOUN
admet-2859	173	26	5	5	NUM
admet-2859	173	27	.	.	PUNCT
admet-2859	174	1	this	this	PRON
admet-2859	174	2	means	mean	VERB
admet-2859	174	3	the	the	DET
admet-2859	174	4	comparison	comparison	NOUN
admet-2859	174	5	of	of	ADP
admet-2859	174	6	the	the	DET
admet-2859	174	7	cases	case	NOUN
admet-2859	174	8	labelled	label	VERB
admet-2859	174	9	‘	'	PUNCT
admet-2859	174	10	cd	cd	NOUN
admet-2859	174	11	-	-	PUNCT
admet-2859	174	12	acceptor	acceptor	NOUN
admet-2859	174	13	’	'	PUNCT
admet-2859	174	14	in	in	ADP
admet-2859	174	15	purple	purple	ADJ
admet-2859	174	16	and	and	CCONJ
admet-2859	174	17	‘	'	PUNCT
admet-2859	174	18	cd	cd	NOUN
admet-2859	174	19	-	-	PUNCT
admet-2859	174	20	both	both	PRON
admet-2859	174	21	’	'	PUNCT
admet-2859	174	22	in	in	ADP
admet-2859	174	23	blue	blue	ADJ
admet-2859	174	24	in	in	ADP
admet-2859	174	25	figure	figure	NOUN
admet-2859	174	26	5	5	NUM
admet-2859	174	27	.	.	PUNCT
admet-2859	175	1	according	accord	VERB
admet-2859	175	2	to	to	ADP
admet-2859	175	3	the	the	DET
admet-2859	175	4	homogeneity	homogeneity	NOUN
admet-2859	175	5	of	of	ADP
admet-2859	175	6	slopes	slope	NOUN
admet-2859	175	7	tests	test	NOUN
admet-2859	175	8	in	in	ADP
admet-2859	175	9	the	the	DET
admet-2859	175	10	case	case	NOUN
admet-2859	175	11	of	of	ADP
admet-2859	175	12	all	all	DET
admet-2859	175	13	three	three	NUM
admet-2859	175	14	membrane	membrane	ADJ
admet-2859	175	15	types	type	NOUN
admet-2859	175	16	,	,	PUNCT
admet-2859	175	17	the	the	DET
admet-2859	175	18	purple	purple	ADJ
admet-2859	175	19	and	and	CCONJ
admet-2859	175	20	blue	blue	ADJ
admet-2859	175	21	lines	line	NOUN
admet-2859	175	22	are	be	AUX
admet-2859	175	23	found	find	VERB
admet-2859	175	24	to	to	PART
admet-2859	175	25	be	be	AUX
admet-2859	175	26	parallel	parallel	VERB
admet-2859	175	27	,	,	PUNCT
admet-2859	175	28	which	which	PRON
admet-2859	175	29	means	mean	VERB
admet-2859	175	30	that	that	SCONJ
admet-2859	175	31	the	the	DET
admet-2859	175	32	effect	effect	NOUN
admet-2859	175	33	of	of	ADP
admet-2859	175	34	cd	cd	PROPN
admet-2859	175	35	placed	place	VERB
admet-2859	175	36	in	in	ADP
admet-2859	175	37	the	the	DET
admet-2859	175	38	donor	donor	NOUN
admet-2859	175	39	compartment	compartment	NOUN
admet-2859	175	40	can	can	AUX
admet-2859	175	41	be	be	AUX
admet-2859	175	42	well	well	ADV
admet-2859	175	43	described	describe	VERB
admet-2859	175	44	by	by	ADP
admet-2859	175	45	equation	equation	NOUN
admet-2859	175	46	(	(	PUNCT
admet-2859	175	47	2	2	NUM
admet-2859	175	48	)	)	PUNCT
admet-2859	175	49	,	,	PUNCT
admet-2859	175	50	regardless	regardless	ADV
admet-2859	175	51	of	of	ADP
admet-2859	175	52	the	the	DET
admet-2859	175	53	type	type	NOUN
admet-2859	175	54	of	of	ADP
admet-2859	175	55	solid	solid	ADJ
admet-2859	175	56	membrane	membrane	NOUN
admet-2859	175	57	.	.	PUNCT
admet-2859	176	1	a	a	DET
admet-2859	176	2	similar	similar	ADJ
admet-2859	176	3	scenario	scenario	NOUN
admet-2859	176	4	was	be	AUX
admet-2859	176	5	previously	previously	ADV
admet-2859	176	6	described	describe	VERB
admet-2859	176	7	[	[	X
admet-2859	176	8	1	1	NUM
admet-2859	176	9	]	]	PUNCT
admet-2859	176	10	in	in	ADP
admet-2859	176	11	which	which	PRON
admet-2859	176	12	the	the	DET
admet-2859	176	13	applicability	applicability	NOUN
admet-2859	176	14	of	of	ADP
admet-2859	176	15	equation	equation	NOUN
admet-2859	176	16	(	(	PUNCT
admet-2859	176	17	2	2	X
admet-2859	176	18	)	)	PUNCT
admet-2859	176	19	was	be	AUX
admet-2859	176	20	evaluated	evaluate	VERB
admet-2859	176	21	with	with	ADP
admet-2859	176	22	cd	cd	PROPN
admet-2859	176	23	placed	place	VERB
admet-2859	176	24	in	in	ADP
admet-2859	176	25	the	the	DET
admet-2859	176	26	donor	donor	NOUN
admet-2859	176	27	compartment	compartment	NOUN
admet-2859	176	28	and	and	CCONJ
admet-2859	176	29	‘	'	PUNCT
admet-2859	176	30	cd	cd	NOUN
admet-2859	176	31	-	-	PUNCT
admet-2859	176	32	none	none	NOUN
admet-2859	176	33	’	'	PUNCT
admet-2859	176	34	buffer	buffer	NOUN
admet-2859	176	35	utilized	utilize	VERB
admet-2859	176	36	as	as	ADP
admet-2859	176	37	acceptor	acceptor	NOUN
admet-2859	176	38	media	medium	NOUN
admet-2859	176	39	.	.	PUNCT
admet-2859	177	1	it	it	PRON
admet-2859	177	2	was	be	AUX
admet-2859	177	3	determined	determine	VERB
admet-2859	177	4	that	that	SCONJ
admet-2859	177	5	equation	equation	NOUN
admet-2859	177	6	(	(	PUNCT
admet-2859	177	7	2	2	X
admet-2859	177	8	)	)	PUNCT
admet-2859	177	9	effectively	effectively	ADV
admet-2859	177	10	represented	represent	VERB
admet-2859	177	11	the	the	DET
admet-2859	177	12	results	result	NOUN
admet-2859	177	13	for	for	ADP
admet-2859	177	14	the	the	DET
admet-2859	177	15	lipophilic	lipophilic	ADJ
admet-2859	177	16	and	and	CCONJ
admet-2859	177	17	size	size	NOUN
admet-2859	177	18	-	-	PUNCT
admet-2859	177	19	exclusion	exclusion	NOUN
admet-2859	177	20	membrane	membrane	NOUN
admet-2859	177	21	with	with	ADP
admet-2859	177	22	1	1	NUM
admet-2859	177	23	kda	kda	NOUN
admet-2859	177	24	mwco	mwco	NOUN
admet-2859	177	25	;	;	PUNCT
admet-2859	177	26	however	however	ADV
admet-2859	177	27	,	,	PUNCT
admet-2859	177	28	for	for	ADP
admet-2859	177	29	the	the	DET
admet-2859	177	30	size	size	NOUN
admet-2859	177	31	-	-	PUNCT
admet-2859	177	32	exclusion	exclusion	NOUN
admet-2859	177	33	membrane	membrane	NOUN
admet-2859	177	34	with	with	ADP
admet-2859	177	35	6	6	NUM
admet-2859	177	36	kda	kda	NOUN
admet-2859	177	37	mwco	mwco	NOUN
admet-2859	177	38	,	,	PUNCT
admet-2859	177	39	the	the	DET
admet-2859	177	40	transport	transport	NOUN
admet-2859	177	41	of	of	ADP
admet-2859	177	42	the	the	DET
admet-2859	177	43	cd	cd	PROPN
admet-2859	177	44	through	through	ADP
admet-2859	177	45	the	the	DET
admet-2859	177	46	membrane	membrane	NOUN
admet-2859	177	47	resulted	result	VERB
admet-2859	177	48	in	in	ADP
admet-2859	177	49	a	a	DET
admet-2859	177	50	significant	significant	ADJ
admet-2859	177	51	deviation	deviation	NOUN
admet-2859	177	52	in	in	ADP
admet-2859	177	53	the	the	DET
admet-2859	177	54	proportionality	proportionality	NOUN
admet-2859	177	55	coefficient	coefficient	NOUN
admet-2859	177	56	.	.	PUNCT
admet-2859	178	1	however	however	ADV
admet-2859	178	2	,	,	PUNCT
admet-2859	178	3	when	when	SCONJ
admet-2859	178	4	the	the	DET
admet-2859	178	5	acceptor	acceptor	NOUN
admet-2859	178	6	side	side	NOUN
admet-2859	178	7	already	already	ADV
admet-2859	178	8	contains	contain	VERB
admet-2859	178	9	an	an	DET
admet-2859	178	10	equivalent	equivalent	ADJ
admet-2859	178	11	concentration	concentration	NOUN
admet-2859	178	12	of	of	ADP
admet-2859	178	13	cd	cd	PROPN
admet-2859	178	14	as	as	ADP
admet-2859	178	15	the	the	DET
admet-2859	178	16	donor	donor	NOUN
admet-2859	178	17	side	side	NOUN
admet-2859	178	18	,	,	PUNCT
admet-2859	178	19	a	a	DET
admet-2859	178	20	concentration	concentration	NOUN
admet-2859	178	21	gradient	gradient	NOUN
admet-2859	178	22	does	do	AUX
admet-2859	178	23	not	not	PART
admet-2859	178	24	exist	exist	VERB
admet-2859	178	25	to	to	PART
admet-2859	178	26	drive	drive	VERB
admet-2859	178	27	the	the	DET
admet-2859	178	28	transport	transport	NOUN
admet-2859	178	29	of	of	ADP
admet-2859	178	30	the	the	DET
admet-2859	178	31	solubilizing	solubilize	VERB
admet-2859	178	32	additive	additive	NOUN
admet-2859	178	33	,	,	PUNCT
admet-2859	178	34	even	even	ADV
admet-2859	178	35	though	though	SCONJ
admet-2859	178	36	the	the	DET
admet-2859	178	37	membrane	membrane	NOUN
admet-2859	178	38	is	be	AUX
admet-2859	178	39	permeable	permeable	ADJ
admet-2859	178	40	to	to	ADP
admet-2859	178	41	cds	cd	NOUN
admet-2859	178	42	.	.	PUNCT
admet-2859	179	1	consequently	consequently	ADV
admet-2859	179	2	,	,	PUNCT
admet-2859	179	3	no	no	DET
admet-2859	179	4	significant	significant	ADJ
admet-2859	179	5	difference	difference	NOUN
admet-2859	179	6	is	be	AUX
admet-2859	179	7	observed	observe	VERB
admet-2859	179	8	in	in	ADP
admet-2859	179	9	the	the	DET
admet-2859	179	10	coefficient	coefficient	NOUN
admet-2859	179	11	of	of	ADP
admet-2859	179	12	proportionalities	proportionality	NOUN
admet-2859	179	13	,	,	PUNCT
admet-2859	179	14	even	even	ADV
admet-2859	179	15	with	with	ADP
admet-2859	179	16	the	the	DET
admet-2859	179	17	size	size	NOUN
admet-2859	179	18	-	-	PUNCT
admet-2859	179	19	exclusion	exclusion	NOUN
admet-2859	179	20	membrane	membrane	NOUN
admet-2859	179	21	with	with	ADP
admet-2859	179	22	6	6	NUM
admet-2859	179	23	kda	kda	NOUN
admet-2859	179	24	mwco	mwco	NOUN
admet-2859	179	25	,	,	PUNCT
admet-2859	179	26	when	when	SCONJ
admet-2859	179	27	comparing	compare	VERB
admet-2859	179	28	the	the	DET
admet-2859	179	29	‘	'	PUNCT
admet-2859	179	30	cd	cd	NOUN
admet-2859	179	31	-	-	PUNCT
admet-2859	179	32	acceptor	acceptor	NOUN
admet-2859	179	33	’	'	PUNCT
admet-2859	179	34	setup	setup	NOUN
admet-2859	179	35	with	with	ADP
admet-2859	179	36	both	both	DET
admet-2859	179	37	instances	instance	NOUN
admet-2859	179	38	(	(	PUNCT
admet-2859	179	39	third	third	ADJ
admet-2859	179	40	column	column	NOUN
admet-2859	179	41	of	of	ADP
admet-2859	179	42	table	table	NOUN
admet-2859	179	43	4	4	NUM
admet-2859	179	44	)	)	PUNCT
admet-2859	179	45	.	.	PUNCT
admet-2859	180	1	conclusions	conclusion	NOUN
admet-2859	180	2	in	in	ADP
admet-2859	180	3	this	this	DET
admet-2859	180	4	study	study	NOUN
admet-2859	180	5	,	,	PUNCT
admet-2859	180	6	the	the	DET
admet-2859	180	7	complex	complex	ADJ
admet-2859	180	8	interplay	interplay	NOUN
admet-2859	180	9	between	between	ADP
admet-2859	180	10	solubility	solubility	NOUN
admet-2859	180	11	enhancement	enhancement	NOUN
admet-2859	180	12	and	and	CCONJ
admet-2859	180	13	membrane	membrane	NOUN
admet-2859	180	14	permeability	permeability	NOUN
admet-2859	180	15	in	in	ADP
admet-2859	180	16	sideby	sideby	ADJ
admet-2859	180	17	-	-	PUNCT
admet-2859	180	18	side	side	NOUN
admet-2859	180	19	diffusion	diffusion	NOUN
admet-2859	180	20	cell	cell	NOUN
admet-2859	180	21	assays	assay	NOUN
admet-2859	180	22	was	be	AUX
admet-2859	180	23	explored	explore	VERB
admet-2859	180	24	,	,	PUNCT
admet-2859	180	25	focusing	focus	VERB
admet-2859	180	26	on	on	ADP
admet-2859	180	27	the	the	DET
admet-2859	180	28	effects	effect	NOUN
admet-2859	180	29	of	of	ADP
admet-2859	180	30	hp	hp	NOUN
admet-2859	180	31	-	-	PUNCT
admet-2859	180	32	β	β	NOUN
admet-2859	180	33	-	-	NOUN
admet-2859	180	34	cd	cd	NOUN
admet-2859	180	35	,	,	PUNCT
admet-2859	180	36	creating	create	VERB
admet-2859	180	37	sink	sink	NOUN
admet-2859	180	38	conditions	condition	NOUN
admet-2859	180	39	.	.	PUNCT
admet-2859	181	1	for	for	ADP
admet-2859	181	2	the	the	DET
admet-2859	181	3	lipophilic	lipophilic	ADJ
admet-2859	181	4	membrane	membrane	NOUN
admet-2859	181	5	,	,	PUNCT
admet-2859	181	6	cds	cd	NOUN
admet-2859	181	7	on	on	ADP
admet-2859	181	8	the	the	DET
admet-2859	181	9	acceptor	acceptor	NOUN
admet-2859	181	10	side	side	NOUN
admet-2859	181	11	significantly	significantly	ADV
admet-2859	181	12	enhanced	enhance	VERB
admet-2859	181	13	flux	flux	NOUN
admet-2859	181	14	and	and	CCONJ
admet-2859	181	15	permeability	permeability	NOUN
admet-2859	181	16	.	.	PUNCT
admet-2859	182	1	conversely	conversely	ADV
admet-2859	182	2	,	,	PUNCT
admet-2859	182	3	with	with	ADP
admet-2859	182	4	size	size	NOUN
admet-2859	182	5	-	-	PUNCT
admet-2859	182	6	exclusion	exclusion	NOUN
admet-2859	182	7	membranes	membrane	NOUN
admet-2859	182	8	that	that	PRON
admet-2859	182	9	allow	allow	VERB
admet-2859	182	10	the	the	DET
admet-2859	182	11	permeation	permeation	NOUN
admet-2859	182	12	of	of	ADP
admet-2859	182	13	cds	cd	NOUN
admet-2859	182	14	and	and	CCONJ
admet-2859	182	15	their	their	PRON
admet-2859	182	16	complexes	complex	NOUN
admet-2859	182	17	,	,	PUNCT
admet-2859	182	18	the	the	DET
admet-2859	182	19	benefits	benefit	NOUN
admet-2859	182	20	of	of	ADP
admet-2859	182	21	sink	sink	NOUN
admet-2859	182	22	conditions	condition	NOUN
admet-2859	182	23	were	be	AUX
admet-2859	182	24	completely	completely	ADV
admet-2859	182	25	diminished	diminish	VERB
admet-2859	182	26	.	.	PUNCT
admet-2859	183	1	the	the	DET
admet-2859	183	2	introduction	introduction	NOUN
admet-2859	183	3	of	of	ADP
admet-2859	183	4	cds	cd	NOUN
admet-2859	183	5	on	on	ADP
admet-2859	183	6	both	both	DET
admet-2859	183	7	sides	side	NOUN
admet-2859	183	8	resulted	result	VERB
admet-2859	183	9	in	in	ADP
admet-2859	183	10	the	the	DET
admet-2859	183	11	negative	negative	ADJ
admet-2859	183	12	impacts	impact	NOUN
admet-2859	183	13	on	on	ADP
admet-2859	183	14	the	the	DET
admet-2859	183	15	donor	donor	NOUN
admet-2859	183	16	side	side	NOUN
admet-2859	183	17	surpassing	surpass	VERB
admet-2859	183	18	the	the	DET
admet-2859	183	19	beneficial	beneficial	ADJ
admet-2859	183	20	sink	sink	NOUN
admet-2859	183	21	effects	effect	NOUN
admet-2859	183	22	on	on	ADP
admet-2859	183	23	the	the	DET
admet-2859	183	24	acceptor	acceptor	NOUN
admet-2859	183	25	side	side	NOUN
admet-2859	183	26	,	,	PUNCT
admet-2859	183	27	hence	hence	ADV
admet-2859	183	28	reducing	reduce	VERB
admet-2859	183	29	flux	flux	NOUN
admet-2859	183	30	and	and	CCONJ
admet-2859	183	31	permeability	permeability	NOUN
admet-2859	183	32	for	for	ADP
admet-2859	183	33	all	all	DET
admet-2859	183	34	membrane	membrane	NOUN
admet-2859	183	35	types	type	NOUN
admet-2859	183	36	.	.	PUNCT
admet-2859	184	1	a	a	DET
admet-2859	184	2	novel	novel	ADJ
admet-2859	184	3	aspect	aspect	NOUN
admet-2859	184	4	of	of	ADP
admet-2859	184	5	this	this	DET
admet-2859	184	6	work	work	NOUN
admet-2859	184	7	is	be	AUX
admet-2859	184	8	the	the	DET
admet-2859	184	9	assessment	assessment	NOUN
admet-2859	184	10	of	of	ADP
admet-2859	184	11	the	the	DET
admet-2859	184	12	applicability	applicability	NOUN
admet-2859	184	13	of	of	ADP
admet-2859	184	14	a	a	DET
admet-2859	184	15	previously	previously	ADV
admet-2859	184	16	described	describe	VERB
admet-2859	184	17	general	general	ADJ
admet-2859	184	18	mathematical	mathematical	ADJ
admet-2859	184	19	equation	equation	NOUN
admet-2859	184	20	for	for	ADP
admet-2859	184	21	sink	sink	NOUN
admet-2859	184	22	conditions	condition	NOUN
admet-2859	184	23	.	.	PUNCT
admet-2859	185	1	this	this	DET
admet-2859	185	2	equation	equation	NOUN
admet-2859	185	3	was	be	AUX
admet-2859	185	4	developed	develop	VERB
admet-2859	185	5	to	to	PART
admet-2859	185	6	describe	describe	VERB
admet-2859	185	7	the	the	DET
admet-2859	185	8	transport	transport	NOUN
admet-2859	185	9	through	through	ADP
admet-2859	185	10	the	the	DET
admet-2859	185	11	uwl	uwl	NOUN
admet-2859	185	12	-	-	PUNCT
admet-2859	185	13	membrane	membrane	NOUN
admet-2859	185	14	-	-	PUNCT
admet-2859	185	15	uwl	uwl	NOUN
admet-2859	185	16	system	system	NOUN
admet-2859	185	17	in	in	ADP
admet-2859	185	18	a	a	DET
admet-2859	185	19	general	general	ADJ
admet-2859	185	20	way	way	NOUN
admet-2859	185	21	,	,	PUNCT
admet-2859	185	22	without	without	ADP
admet-2859	185	23	specifying	specify	VERB
admet-2859	185	24	what	what	DET
admet-2859	185	25	type	type	NOUN
admet-2859	185	26	of	of	ADP
admet-2859	185	27	membrane	membrane	NOUN
admet-2859	185	28	is	be	AUX
admet-2859	185	29	between	between	ADP
admet-2859	185	30	the	the	DET
admet-2859	185	31	two	two	NUM
admet-2859	185	32	uwl	uwl	NOUN
admet-2859	185	33	layers	layer	NOUN
admet-2859	185	34	.	.	PUNCT
admet-2859	186	1	this	this	DET
admet-2859	186	2	model	model	NOUN
admet-2859	186	3	was	be	AUX
admet-2859	186	4	used	use	VERB
admet-2859	186	5	to	to	PART
admet-2859	186	6	describe	describe	VERB
admet-2859	186	7	the	the	DET
admet-2859	186	8	effect	effect	NOUN
admet-2859	186	9	of	of	ADP
admet-2859	186	10	cd	cd	PROPN
admet-2859	186	11	in	in	ADP
admet-2859	186	12	the	the	DET
admet-2859	186	13	donor	donor	NOUN
admet-2859	186	14	compartment	compartment	NOUN
admet-2859	186	15	on	on	ADP
admet-2859	186	16	the	the	DET
admet-2859	186	17	api	api	NOUN
admet-2859	186	18	transport	transport	NOUN
admet-2859	186	19	for	for	ADP
admet-2859	186	20	lipophilic	lipophilic	ADJ
admet-2859	186	21	and	and	CCONJ
admet-2859	186	22	size	size	NOUN
admet-2859	186	23	-	-	PUNCT
admet-2859	186	24	exclusion	exclusion	NOUN
admet-2859	186	25	membranes	membrane	NOUN
admet-2859	186	26	with	with	ADP
admet-2859	186	27	mwcos	mwco	NOUN
admet-2859	186	28	1	1	NUM
admet-2859	186	29	and	and	CCONJ
admet-2859	186	30	6	6	NUM
admet-2859	186	31	kda	kda	NOUN
admet-2859	186	32	.	.	PUNCT
admet-2859	187	1	experimental	experimental	ADJ
admet-2859	187	2	results	result	NOUN
admet-2859	187	3	confirmed	confirm	VERB
admet-2859	187	4	the	the	DET
admet-2859	187	5	applicability	applicability	NOUN
admet-2859	187	6	of	of	ADP
admet-2859	187	7	the	the	DET
admet-2859	187	8	model	model	NOUN
admet-2859	187	9	when	when	SCONJ
admet-2859	187	10	the	the	DET
admet-2859	187	11	membrane	membrane	NOUN
admet-2859	187	12	is	be	AUX
admet-2859	187	13	selectively	selectively	ADV
admet-2859	187	14	permeable	permeable	ADJ
admet-2859	187	15	for	for	ADP
admet-2859	187	16	the	the	DET
admet-2859	187	17	drug	drug	NOUN
admet-2859	187	18	(	(	PUNCT
admet-2859	187	19	lipophilic	lipophilic	ADJ
admet-2859	187	20	membrane	membrane	NOUN
admet-2859	187	21	)	)	PUNCT
admet-2859	187	22	or	or	CCONJ
admet-2859	187	23	when	when	SCONJ
admet-2859	187	24	the	the	DET
admet-2859	187	25	permeation	permeation	NOUN
admet-2859	187	26	of	of	ADP
admet-2859	187	27	the	the	DET
admet-2859	187	28	solubilizing	solubilizing	NOUN
admet-2859	187	29	additive	additive	NOUN
admet-2859	187	30	is	be	AUX
admet-2859	187	31	negligibly	negligibly	ADV
admet-2859	187	32	slow	slow	ADJ
admet-2859	187	33	(	(	PUNCT
admet-2859	187	34	1	1	NUM
admet-2859	187	35	kda	kda	NOUN
admet-2859	187	36	mwco	mwco	NOUN
admet-2859	187	37	)	)	PUNCT
admet-2859	188	1	[	[	X
admet-2859	188	2	1	1	NUM
admet-2859	188	3	]	]	PUNCT
admet-2859	188	4	.	.	PUNCT
admet-2859	189	1	in	in	ADP
admet-2859	189	2	this	this	DET
admet-2859	189	3	paper	paper	NOUN
admet-2859	189	4	,	,	PUNCT
admet-2859	189	5	the	the	DET
admet-2859	189	6	applicability	applicability	NOUN
admet-2859	189	7	of	of	ADP
admet-2859	189	8	this	this	DET
admet-2859	189	9	model	model	NOUN
admet-2859	189	10	was	be	AUX
admet-2859	189	11	further	far	ADV
admet-2859	189	12	assessed	assess	VERB
admet-2859	189	13	in	in	ADP
admet-2859	189	14	sink	sink	NOUN
admet-2859	189	15	conditions	condition	NOUN
admet-2859	189	16	.	.	PUNCT
admet-2859	190	1	for	for	ADP
admet-2859	190	2	the	the	DET
admet-2859	190	3	lipophilic	lipophilic	ADJ
admet-2859	190	4	membrane	membrane	NOUN
admet-2859	190	5	,	,	PUNCT
admet-2859	190	6	where	where	SCONJ
admet-2859	190	7	the	the	DET
admet-2859	190	8	sink	sink	NOUN
admet-2859	190	9	effect	effect	NOUN
admet-2859	190	10	had	have	VERB
admet-2859	190	11	a	a	DET
admet-2859	190	12	significant	significant	ADJ
admet-2859	190	13	impact	impact	NOUN
admet-2859	190	14	on	on	ADP
admet-2859	190	15	the	the	DET
admet-2859	190	16	permeability	permeability	NOUN
admet-2859	190	17	,	,	PUNCT
admet-2859	190	18	a	a	DET
admet-2859	190	19	significantly	significantly	ADV
admet-2859	190	20	higher	high	ADJ
admet-2859	190	21	proportionality	proportionality	NOUN
admet-2859	190	22	coefficient	coefficient	NOUN
admet-2859	190	23	was	be	AUX
admet-2859	190	24	observed	observe	VERB
admet-2859	190	25	with	with	ADP
admet-2859	190	26	cd	cd	PROPN
admet-2859	190	27	placed	place	VERB
admet-2859	190	28	on	on	ADP
admet-2859	190	29	the	the	DET
admet-2859	190	30	acceptor	acceptor	NOUN
admet-2859	190	31	side	side	NOUN
admet-2859	190	32	compared	compare	VERB
admet-2859	190	33	to	to	ADP
admet-2859	190	34	the	the	DET
admet-2859	190	35	‘	'	PUNCT
admet-2859	190	36	cd	cd	NOUN
admet-2859	190	37	-	-	PUNCT
admet-2859	190	38	none	none	NOUN
admet-2859	190	39	’	'	PUNCT
admet-2859	190	40	buffer	buffer	NOUN
admet-2859	190	41	.	.	PUNCT
admet-2859	191	1	this	this	DET
admet-2859	191	2	phenomenon	phenomenon	NOUN
admet-2859	191	3	might	might	AUX
admet-2859	191	4	be	be	AUX
admet-2859	191	5	explained	explain	VERB
admet-2859	191	6	by	by	ADP
admet-2859	191	7	the	the	DET
admet-2859	191	8	fact	fact	NOUN
admet-2859	191	9	that	that	SCONJ
admet-2859	191	10	cd	cd	PROPN
admet-2859	191	11	not	not	PART
admet-2859	191	12	only	only	ADV
admet-2859	191	13	influences	influence	VERB
admet-2859	191	14	the	the	DET
admet-2859	191	15	solubility	solubility	NOUN
admet-2859	191	16	of	of	ADP
admet-2859	191	17	the	the	DET
admet-2859	191	18	api	api	NOUN
admet-2859	191	19	on	on	ADP
admet-2859	191	20	the	the	DET
admet-2859	191	21	acceptor	acceptor	NOUN
admet-2859	191	22	side	side	NOUN
admet-2859	191	23	,	,	PUNCT
admet-2859	191	24	but	but	CCONJ
admet-2859	191	25	also	also	ADV
admet-2859	191	26	the	the	DET
admet-2859	191	27	hydrophilicity	hydrophilicity	NOUN
admet-2859	191	28	of	of	ADP
admet-2859	191	29	the	the	DET
admet-2859	191	30	drug	drug	NOUN
admet-2859	191	31	-	-	PUNCT
admet-2859	191	32	cd	cd	NOUN
admet-2859	191	33	complex	complex	NOUN
admet-2859	191	34	is	be	AUX
admet-2859	191	35	much	much	ADV
admet-2859	191	36	higher	high	ADJ
admet-2859	191	37	than	than	ADP
admet-2859	191	38	that	that	PRON
admet-2859	191	39	of	of	ADP
admet-2859	191	40	the	the	DET
admet-2859	191	41	pure	pure	ADJ
admet-2859	191	42	api	api	NOUN
admet-2859	191	43	’s	’s	NOUN
admet-2859	191	44	;	;	PUNCT
admet-2859	191	45	therefore	therefore	ADV
admet-2859	191	46	,	,	PUNCT
admet-2859	191	47	the	the	DET
admet-2859	191	48	thickness	thickness	NOUN
admet-2859	191	49	of	of	ADP
admet-2859	191	50	the	the	DET
admet-2859	191	51	uwl	uwl	NOUN
admet-2859	191	52	becomes	become	VERB
admet-2859	191	53	negligible	negligible	ADJ
admet-2859	191	54	for	for	ADP
admet-2859	191	55	the	the	DET
admet-2859	191	56	complex	complex	NOUN
admet-2859	191	57	.	.	PUNCT
admet-2859	192	1	this	this	PRON
admet-2859	192	2	leads	lead	VERB
admet-2859	192	3	to	to	ADP
admet-2859	192	4	reduced	reduce	VERB
admet-2859	192	5	apparent	apparent	ADJ
admet-2859	192	6	uwl	uwl	NOUN
admet-2859	192	7	thickness	thickness	NOUN
admet-2859	192	8	(	(	PUNCT
admet-2859	192	9	h	h	NOUN
admet-2859	192	10	)	)	PUNCT
admet-2859	192	11	and	and	CCONJ
admet-2859	192	12	increased	increase	VERB
admet-2859	192	13	puwl	puwl	ADJ
admet-2859	192	14	values	value	NOUN
admet-2859	192	15	(	(	PUNCT
admet-2859	192	16	table	table	NOUN
admet-2859	192	17	3	3	NUM
admet-2859	192	18	)	)	PUNCT
admet-2859	193	1	[	[	X
admet-2859	193	2	46	46	NUM
admet-2859	193	3	]	]	PUNCT
admet-2859	193	4	.	.	PUNCT
admet-2859	194	1	in	in	ADP
admet-2859	194	2	contrast	contrast	NOUN
admet-2859	194	3	,	,	PUNCT
admet-2859	194	4	with	with	ADP
admet-2859	194	5	size	size	NOUN
admet-2859	194	6	-	-	PUNCT
admet-2859	194	7	exclusion	exclusion	NOUN
admet-2859	194	8	membranes	membrane	NOUN
admet-2859	194	9	,	,	PUNCT
admet-2859	194	10	where	where	SCONJ
admet-2859	194	11	the	the	DET
admet-2859	194	12	admet	admet	PROPN
admet-2859	194	13	&	&	CCONJ
admet-2859	194	14	dmpk	dmpk	PROPN
admet-2859	194	15	13(5	13(5	NOUN
admet-2859	194	16	)	)	PUNCT
admet-2859	194	17	(	(	PUNCT
admet-2859	194	18	2025	2025	NUM
admet-2859	194	19	)	)	PUNCT
admet-2859	194	20	2859	2859	NUM
admet-2859	194	21	comparison	comparison	NOUN
admet-2859	194	22	of	of	ADP
admet-2859	194	23	lipophilic	lipophilic	ADJ
admet-2859	194	24	and	and	CCONJ
admet-2859	194	25	size	size	NOUN
admet-2859	194	26	-	-	PUNCT
admet-2859	194	27	exclusion	exclusion	NOUN
admet-2859	194	28	membranes	membrane	NOUN
admet-2859	194	29	doi	doi	NOUN
admet-2859	194	30	:	:	PUNCT
admet-2859	194	31	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	X
admet-2859	194	32	11	11	NUM
admet-2859	194	33	cds	cd	NOUN
admet-2859	194	34	and	and	CCONJ
admet-2859	194	35	their	their	PRON
admet-2859	194	36	complexes	complex	NOUN
admet-2859	194	37	can	can	AUX
admet-2859	194	38	permeate	permeate	VERB
admet-2859	194	39	the	the	DET
admet-2859	194	40	membrane	membrane	NOUN
admet-2859	194	41	,	,	PUNCT
admet-2859	194	42	the	the	DET
admet-2859	194	43	effect	effect	NOUN
admet-2859	194	44	of	of	ADP
admet-2859	194	45	the	the	DET
admet-2859	194	46	sink	sink	NOUN
admet-2859	194	47	condition	condition	NOUN
admet-2859	194	48	was	be	AUX
admet-2859	194	49	negated	negate	VERB
admet-2859	194	50	,	,	PUNCT
admet-2859	194	51	resulting	result	VERB
admet-2859	194	52	in	in	ADP
admet-2859	194	53	no	no	DET
admet-2859	194	54	significant	significant	ADJ
admet-2859	194	55	difference	difference	NOUN
admet-2859	194	56	in	in	ADP
admet-2859	194	57	the	the	DET
admet-2859	194	58	coefficient	coefficient	NOUN
admet-2859	194	59	of	of	ADP
admet-2859	194	60	proportionality	proportionality	NOUN
admet-2859	194	61	.	.	PUNCT
admet-2859	195	1	in	in	ADP
admet-2859	195	2	formulation	formulation	NOUN
admet-2859	195	3	development	development	NOUN
admet-2859	195	4	,	,	PUNCT
admet-2859	195	5	the	the	DET
admet-2859	195	6	typical	typical	ADJ
admet-2859	195	7	scenario	scenario	NOUN
admet-2859	195	8	involves	involve	VERB
admet-2859	195	9	the	the	DET
admet-2859	195	10	formulation	formulation	NOUN
admet-2859	195	11	releasing	release	VERB
admet-2859	195	12	solubilizing	solubilize	VERB
admet-2859	195	13	additives	additive	NOUN
admet-2859	195	14	in	in	ADP
admet-2859	195	15	the	the	DET
admet-2859	195	16	donor	donor	NOUN
admet-2859	195	17	compartment	compartment	NOUN
admet-2859	195	18	while	while	SCONJ
admet-2859	195	19	surfactants	surfactant	NOUN
admet-2859	195	20	or	or	CCONJ
admet-2859	195	21	cds	cd	NOUN
admet-2859	195	22	are	be	AUX
admet-2859	195	23	used	use	VERB
admet-2859	195	24	in	in	ADP
admet-2859	195	25	the	the	DET
admet-2859	195	26	acceptor	acceptor	NOUN
admet-2859	195	27	compartment	compartment	NOUN
admet-2859	195	28	to	to	PART
admet-2859	195	29	create	create	VERB
admet-2859	195	30	a	a	DET
admet-2859	195	31	sink	sink	NOUN
admet-2859	195	32	condition	condition	NOUN
admet-2859	195	33	.	.	PUNCT
admet-2859	196	1	therefore	therefore	ADV
admet-2859	196	2	,	,	PUNCT
admet-2859	196	3	the	the	DET
admet-2859	196	4	effect	effect	NOUN
admet-2859	196	5	of	of	ADP
admet-2859	196	6	placing	place	VERB
admet-2859	196	7	the	the	DET
admet-2859	196	8	same	same	ADJ
admet-2859	196	9	amount	amount	NOUN
admet-2859	196	10	of	of	ADP
admet-2859	196	11	cd	cd	PROPN
admet-2859	196	12	on	on	ADP
admet-2859	196	13	the	the	DET
admet-2859	196	14	donor	donor	NOUN
admet-2859	196	15	side	side	NOUN
admet-2859	196	16	as	as	ADP
admet-2859	196	17	on	on	ADP
admet-2859	196	18	the	the	DET
admet-2859	196	19	acceptor	acceptor	NOUN
admet-2859	196	20	side	side	NOUN
admet-2859	196	21	was	be	AUX
admet-2859	196	22	also	also	ADV
admet-2859	196	23	evaluated	evaluate	VERB
admet-2859	196	24	.	.	PUNCT
admet-2859	197	1	the	the	DET
admet-2859	197	2	effect	effect	NOUN
admet-2859	197	3	of	of	ADP
admet-2859	197	4	the	the	DET
admet-2859	197	5	cd	cd	PROPN
admet-2859	197	6	placed	place	VERB
admet-2859	197	7	in	in	ADP
admet-2859	197	8	the	the	DET
admet-2859	197	9	donor	donor	NOUN
admet-2859	197	10	compartment	compartment	NOUN
admet-2859	197	11	can	can	AUX
admet-2859	197	12	be	be	AUX
admet-2859	197	13	accurately	accurately	ADV
admet-2859	197	14	described	describe	VERB
admet-2859	197	15	by	by	ADP
admet-2859	197	16	the	the	DET
admet-2859	197	17	general	general	ADJ
admet-2859	197	18	mathematical	mathematical	ADJ
admet-2859	197	19	equation	equation	NOUN
admet-2859	197	20	,	,	PUNCT
admet-2859	197	21	regardless	regardless	ADV
admet-2859	197	22	of	of	ADP
admet-2859	197	23	the	the	DET
admet-2859	197	24	solid	solid	ADJ
admet-2859	197	25	membrane	membrane	NOUN
admet-2859	197	26	type	type	NOUN
admet-2859	197	27	.	.	PUNCT
admet-2859	198	1	these	these	DET
admet-2859	198	2	results	result	NOUN
admet-2859	198	3	were	be	AUX
admet-2859	198	4	compared	compare	VERB
admet-2859	198	5	with	with	ADP
admet-2859	198	6	previously	previously	ADV
admet-2859	198	7	published	publish	VERB
admet-2859	198	8	data	datum	NOUN
admet-2859	198	9	,	,	PUNCT
admet-2859	198	10	concluding	conclude	VERB
admet-2859	198	11	that	that	SCONJ
admet-2859	198	12	this	this	DET
admet-2859	198	13	universal	universal	ADJ
admet-2859	198	14	equation	equation	NOUN
admet-2859	198	15	effectively	effectively	ADV
admet-2859	198	16	describes	describe	VERB
admet-2859	198	17	the	the	DET
admet-2859	198	18	impact	impact	NOUN
admet-2859	198	19	of	of	ADP
admet-2859	198	20	cd	cd	PROPN
admet-2859	198	21	placed	place	VERB
admet-2859	198	22	on	on	ADP
admet-2859	198	23	the	the	DET
admet-2859	198	24	donor	donor	NOUN
admet-2859	198	25	side	side	NOUN
admet-2859	198	26	.	.	PUNCT
admet-2859	199	1	this	this	PRON
admet-2859	199	2	occurs	occur	VERB
admet-2859	199	3	when	when	SCONJ
admet-2859	199	4	the	the	DET
admet-2859	199	5	solid	solid	ADJ
admet-2859	199	6	membrane	membrane	NOUN
admet-2859	199	7	permits	permit	VERB
admet-2859	199	8	only	only	ADV
admet-2859	199	9	the	the	DET
admet-2859	199	10	drug	drug	NOUN
admet-2859	199	11	’s	’s	PART
admet-2859	199	12	permeation	permeation	NOUN
admet-2859	199	13	,	,	PUNCT
admet-2859	199	14	as	as	ADP
admet-2859	199	15	in	in	ADP
admet-2859	199	16	a	a	DET
admet-2859	199	17	lipophilic	lipophilic	ADJ
admet-2859	199	18	membrane	membrane	NOUN
admet-2859	199	19	,	,	PUNCT
admet-2859	199	20	where	where	SCONJ
admet-2859	199	21	the	the	DET
admet-2859	199	22	solubilizing	solubilizing	NOUN
admet-2859	199	23	additive	additive	NOUN
admet-2859	199	24	is	be	AUX
admet-2859	199	25	unable	unable	ADJ
admet-2859	199	26	to	to	PART
admet-2859	199	27	go	go	VERB
admet-2859	199	28	through	through	ADP
admet-2859	199	29	due	due	ADP
admet-2859	199	30	to	to	ADP
admet-2859	199	31	its	its	PRON
admet-2859	199	32	size	size	NOUN
admet-2859	199	33	or	or	CCONJ
admet-2859	199	34	lipophilicity	lipophilicity	NOUN
admet-2859	199	35	.	.	PUNCT
admet-2859	200	1	it	it	PRON
admet-2859	200	2	also	also	ADV
admet-2859	200	3	applies	apply	VERB
admet-2859	200	4	when	when	SCONJ
admet-2859	200	5	the	the	DET
admet-2859	200	6	permeation	permeation	NOUN
admet-2859	200	7	of	of	ADP
admet-2859	200	8	the	the	DET
admet-2859	200	9	solubilizing	solubilizing	NOUN
admet-2859	200	10	additive	additive	NOUN
admet-2859	200	11	is	be	AUX
admet-2859	200	12	sufficiently	sufficiently	ADV
admet-2859	200	13	slow	slow	ADJ
admet-2859	200	14	,	,	PUNCT
admet-2859	200	15	thus	thus	ADV
admet-2859	200	16	not	not	PART
admet-2859	200	17	significantly	significantly	ADV
admet-2859	200	18	affecting	affect	VERB
admet-2859	200	19	the	the	DET
admet-2859	200	20	transport	transport	NOUN
admet-2859	200	21	,	,	PUNCT
admet-2859	200	22	as	as	SCONJ
admet-2859	200	23	observed	observe	VERB
admet-2859	200	24	with	with	ADP
admet-2859	200	25	a	a	DET
admet-2859	200	26	size	size	NOUN
admet-2859	200	27	-	-	PUNCT
admet-2859	200	28	exclusion	exclusion	NOUN
admet-2859	200	29	membrane	membrane	NOUN
admet-2859	200	30	with	with	ADP
admet-2859	200	31	1kda	1kda	PROPN
admet-2859	200	32	mwco	mwco	NOUN
admet-2859	200	33	.	.	PUNCT
admet-2859	201	1	furthermore	furthermore	ADV
admet-2859	201	2	,	,	PUNCT
admet-2859	201	3	the	the	DET
admet-2859	201	4	model	model	NOUN
admet-2859	201	5	remains	remain	VERB
admet-2859	201	6	suitable	suitable	ADJ
admet-2859	201	7	if	if	SCONJ
admet-2859	201	8	the	the	DET
admet-2859	201	9	additive	additive	NOUN
admet-2859	201	10	is	be	AUX
admet-2859	201	11	small	small	ADJ
admet-2859	201	12	enough	enough	ADV
admet-2859	201	13	in	in	ADP
admet-2859	201	14	hydrodynamic	hydrodynamic	ADJ
admet-2859	201	15	size	size	NOUN
admet-2859	201	16	to	to	PART
admet-2859	201	17	permeate	permeate	VERB
admet-2859	201	18	the	the	DET
admet-2859	201	19	membrane	membrane	NOUN
admet-2859	201	20	yet	yet	ADV
admet-2859	201	21	lacks	lack	VERB
admet-2859	201	22	a	a	DET
admet-2859	201	23	concentration	concentration	NOUN
admet-2859	201	24	gradient	gradient	NOUN
admet-2859	201	25	to	to	PART
admet-2859	201	26	drive	drive	VERB
admet-2859	201	27	the	the	DET
admet-2859	201	28	transport	transport	NOUN
admet-2859	201	29	of	of	ADP
admet-2859	201	30	the	the	DET
admet-2859	201	31	solubilizing	solubilize	VERB
admet-2859	201	32	agent	agent	NOUN
admet-2859	201	33	,	,	PUNCT
admet-2859	201	34	such	such	ADJ
admet-2859	201	35	as	as	ADP
admet-2859	201	36	with	with	ADP
admet-2859	201	37	6	6	NUM
admet-2859	201	38	kda	kda	NOUN
admet-2859	201	39	mwco	mwco	NOUN
admet-2859	201	40	sizeexclusion	sizeexclusion	PROPN
admet-2859	201	41	membrane	membrane	NOUN
admet-2859	201	42	with	with	ADP
admet-2859	201	43	the	the	DET
admet-2859	201	44	same	same	ADJ
admet-2859	201	45	cd	cd	NOUN
admet-2859	201	46	concentrations	concentration	NOUN
admet-2859	201	47	on	on	ADP
admet-2859	201	48	both	both	DET
admet-2859	201	49	sides	side	NOUN
admet-2859	201	50	of	of	ADP
admet-2859	201	51	the	the	DET
admet-2859	201	52	membrane	membrane	NOUN
admet-2859	201	53	.	.	PUNCT
admet-2859	202	1	‘	'	PUNCT
admet-2859	202	2	in	in	ADP
admet-2859	202	3	conclusion	conclusion	NOUN
admet-2859	202	4	,	,	PUNCT
admet-2859	202	5	this	this	DET
admet-2859	202	6	study	study	NOUN
admet-2859	202	7	elucidates	elucidate	VERB
admet-2859	202	8	a	a	DET
admet-2859	202	9	deeper	deep	ADJ
admet-2859	202	10	understanding	understanding	NOUN
admet-2859	202	11	of	of	ADP
admet-2859	202	12	the	the	DET
admet-2859	202	13	mechanistic	mechanistic	ADJ
admet-2859	202	14	effects	effect	NOUN
admet-2859	202	15	of	of	ADP
admet-2859	202	16	cds	cd	NOUN
admet-2859	202	17	in	in	ADP
admet-2859	202	18	side	side	NOUN
admet-2859	202	19	-	-	PUNCT
admet-2859	202	20	byside	byside	NOUN
admet-2859	202	21	diffusion	diffusion	NOUN
admet-2859	202	22	cell	cell	NOUN
admet-2859	202	23	assays	assay	NOUN
admet-2859	202	24	,	,	PUNCT
admet-2859	202	25	providing	provide	VERB
admet-2859	202	26	a	a	DET
admet-2859	202	27	valuable	valuable	ADJ
admet-2859	202	28	framework	framework	NOUN
admet-2859	202	29	for	for	ADP
admet-2859	202	30	optimization	optimization	NOUN
admet-2859	202	31	of	of	ADP
admet-2859	202	32	drug	drug	NOUN
admet-2859	202	33	formulations	formulation	NOUN
admet-2859	202	34	.	.	PUNCT
admet-2859	203	1	acknowledgements	acknowledgement	NOUN
admet-2859	203	2	:	:	PUNCT
admet-2859	203	3	this	this	DET
admet-2859	203	4	work	work	NOUN
admet-2859	203	5	was	be	AUX
admet-2859	203	6	supported	support	VERB
admet-2859	203	7	by	by	ADP
admet-2859	203	8	eköp-24	eköp-24	PROPN
admet-2859	203	9	-	-	PUNCT
admet-2859	203	10	4	4	NUM
admet-2859	203	11	-	-	PUNCT
admet-2859	203	12	i	i	PRON
admet-2859	203	13	-	-	PUNCT
admet-2859	203	14	bme-127	bme-127	PROPN
admet-2859	203	15	university	university	PROPN
admet-2859	203	16	research	research	NOUN
admet-2859	203	17	fellowship	fellowship	NOUN
admet-2859	203	18	programme	programme	NOUN
admet-2859	203	19	of	of	ADP
admet-2859	203	20	the	the	DET
admet-2859	203	21	ministry	ministry	PROPN
admet-2859	203	22	for	for	ADP
admet-2859	203	23	culture	culture	NOUN
admet-2859	203	24	and	and	CCONJ
admet-2859	203	25	innovation	innovation	NOUN
admet-2859	203	26	from	from	ADP
admet-2859	203	27	the	the	DET
admet-2859	203	28	source	source	NOUN
admet-2859	203	29	of	of	ADP
admet-2859	203	30	the	the	DET
admet-2859	203	31	national	national	ADJ
admet-2859	203	32	research	research	NOUN
admet-2859	203	33	.	.	PUNCT
admet-2859	204	1	this	this	DET
admet-2859	204	2	work	work	NOUN
admet-2859	204	3	was	be	AUX
admet-2859	204	4	financially	financially	ADV
admet-2859	204	5	supported	support	VERB
admet-2859	204	6	by	by	ADP
admet-2859	204	7	the	the	DET
admet-2859	204	8	janos	janos	PROPN
admet-2859	204	9	bolyai	bolyai	PROPN
admet-2859	204	10	research	research	NOUN
admet-2859	204	11	scholarship	scholarship	NOUN
admet-2859	204	12	of	of	ADP
admet-2859	204	13	the	the	DET
admet-2859	204	14	hungarian	hungarian	ADJ
admet-2859	204	15	academy	academy	PROPN
admet-2859	204	16	of	of	ADP
admet-2859	204	17	sciences	sciences	PROPN
admet-2859	204	18	.	.	PUNCT
admet-2859	205	1	project	project	PROPN
admet-2859	205	2	no	no	NOUN
admet-2859	205	3	.	.	NOUN
admet-2859	206	1	2024	2024	NUM
admet-2859	206	2	-	-	PUNCT
admet-2859	206	3	1.1.1	1.1.1	NUM
admet-2859	206	4	-	-	PUNCT
admet-2859	206	5	kkv_fókusz-2024	kkv_fókusz-2024	NOUN
admet-2859	206	6	-	-	PUNCT
admet-2859	206	7	00051	00051	NUM
admet-2859	206	8	has	have	AUX
admet-2859	206	9	been	be	AUX
admet-2859	206	10	implemented	implement	VERB
admet-2859	206	11	with	with	ADP
admet-2859	206	12	the	the	DET
admet-2859	206	13	support	support	NOUN
admet-2859	206	14	provided	provide	VERB
admet-2859	206	15	by	by	ADP
admet-2859	206	16	the	the	DET
admet-2859	206	17	ministry	ministry	PROPN
admet-2859	206	18	of	of	ADP
admet-2859	206	19	culture	culture	NOUN
admet-2859	206	20	and	and	CCONJ
admet-2859	206	21	innovation	innovation	NOUN
admet-2859	206	22	of	of	ADP
admet-2859	206	23	hungary	hungary	PROPN
admet-2859	206	24	from	from	ADP
admet-2859	206	25	the	the	DET
admet-2859	206	26	national	national	ADJ
admet-2859	206	27	research	research	NOUN
admet-2859	206	28	,	,	PUNCT
admet-2859	206	29	development	development	NOUN
admet-2859	206	30	and	and	CCONJ
admet-2859	206	31	innovation	innovation	NOUN
admet-2859	206	32	fund	fund	NOUN
admet-2859	206	33	,	,	PUNCT
admet-2859	206	34	financed	finance	VERB
admet-2859	206	35	under	under	ADP
admet-2859	206	36	the	the	DET
admet-2859	206	37	‘	'	PUNCT
admet-2859	206	38	kkv	kkv	VERB
admet-2859	206	39	fókuszterületi	fókuszterületi	ADJ
admet-2859	206	40	innovációs	innovációs	ADJ
admet-2859	206	41	program	program	NOUN
admet-2859	206	42	’	'	PUNCT
admet-2859	206	43	funding	funding	NOUN
admet-2859	206	44	scheme	scheme	NOUN
admet-2859	206	45	.	.	PUNCT
admet-2859	207	1	conflict	conflict	NOUN
admet-2859	207	2	of	of	ADP
admet-2859	207	3	interest	interest	NOUN
admet-2859	207	4	:	:	PUNCT
admet-2859	207	5	the	the	DET
admet-2859	207	6	authors	author	NOUN
admet-2859	207	7	declare	declare	VERB
admet-2859	207	8	no	no	DET
admet-2859	207	9	conflict	conflict	NOUN
admet-2859	207	10	of	of	ADP
admet-2859	207	11	interest	interest	NOUN
admet-2859	207	12	.	.	PUNCT
admet-2859	208	1	references	reference	NOUN
admet-2859	208	2	[	[	X
admet-2859	208	3	1	1	NUM
admet-2859	208	4	]	]	PUNCT
admet-2859	208	5	p.	p.	PROPN
admet-2859	208	6	tőzsér	tőzsér	PROPN
admet-2859	208	7	,	,	PUNCT
admet-2859	208	8	s.	s.	PROPN
admet-2859	208	9	kádár	kádár	PROPN
admet-2859	208	10	,	,	PUNCT
admet-2859	208	11	e.	e.	PROPN
admet-2859	208	12	szabó	szabó	PROPN
admet-2859	208	13	,	,	PUNCT
admet-2859	208	14	m.	m.	NOUN
admet-2859	208	15	dobó	dobó	PROPN
admet-2859	208	16	,	,	PUNCT
admet-2859	208	17	g.	g.	PROPN
admet-2859	208	18	tóth	tóth	PROPN
admet-2859	208	19	,	,	PUNCT
admet-2859	208	20	g.t	g.t	PROPN
admet-2859	208	21	.	.	PROPN
admet-2859	208	22	balogh	balogh	PROPN
admet-2859	208	23	,	,	PUNCT
admet-2859	208	24	p.	p.	PROPN
admet-2859	208	25	sóti	sóti	PROPN
admet-2859	208	26	,	,	PUNCT
admet-2859	208	27	b.	b.	PROPN
admet-2859	208	28	sinkó	sinkó	PROPN
admet-2859	208	29	,	,	PUNCT
admet-2859	208	30	e.	e.	PROPN
admet-2859	208	31	borbás	borbás	PROPN
admet-2859	208	32	.	.	PUNCT
admet-2859	209	1	comparison	comparison	NOUN
admet-2859	209	2	of	of	ADP
admet-2859	209	3	lipophilic	lipophilic	ADJ
admet-2859	209	4	and	and	CCONJ
admet-2859	209	5	size	size	NOUN
admet-2859	209	6	-	-	PUNCT
admet-2859	209	7	exclusion	exclusion	NOUN
admet-2859	209	8	membranes	membrane	NOUN
admet-2859	209	9	:	:	PUNCT
admet-2859	209	10	the	the	DET
admet-2859	209	11	effect	effect	NOUN
admet-2859	209	12	of	of	ADP
admet-2859	209	13	stirring	stirring	NOUN
admet-2859	209	14	and	and	CCONJ
admet-2859	209	15	cyclodextrin	cyclodextrin	NOUN
admet-2859	209	16	in	in	ADP
admet-2859	209	17	the	the	DET
admet-2859	209	18	donor	donor	NOUN
admet-2859	209	19	compartment	compartment	NOUN
admet-2859	209	20	.	.	PUNCT
admet-2859	210	1	admet	admet	PROPN
admet-2859	210	2	and	and	CCONJ
admet-2859	210	3	dmpk	dmpk	PROPN
admet-2859	210	4	13(4	13(4	NUM
admet-2859	210	5	)	)	PUNCT
admet-2859	210	6	(	(	PUNCT
admet-2859	210	7	2025	2025	NUM
admet-2859	210	8	)	)	PUNCT
admet-2859	210	9	2753	2753	NUM
admet-2859	210	10	.	.	PUNCT
admet-2859	211	1	https://doi.org/10.5599/admet.2753	https://doi.org/10.5599/admet.2753	PROPN
admet-2859	211	2	[	[	X
admet-2859	211	3	2	2	NUM
admet-2859	211	4	]	]	PUNCT
admet-2859	211	5	a.	a.	NOUN
admet-2859	211	6	sitovs	sitovs	PROPN
admet-2859	211	7	,	,	PUNCT
admet-2859	211	8	v.	v.	PROPN
admet-2859	211	9	mohylyuk	mohylyuk	NOUN
admet-2859	211	10	.	.	PUNCT
admet-2859	212	1	ex	ex	PRON
admet-2859	212	2	vivo	vivo	ADJ
admet-2859	212	3	permeability	permeability	NOUN
admet-2859	212	4	study	study	NOUN
admet-2859	212	5	of	of	ADP
admet-2859	212	6	poorly	poorly	ADV
admet-2859	212	7	soluble	soluble	ADJ
admet-2859	212	8	drugs	drug	NOUN
admet-2859	212	9	across	across	ADP
admet-2859	212	10	gastrointestinal	gastrointestinal	ADJ
admet-2859	212	11	membranes	membrane	NOUN
admet-2859	212	12	:	:	PUNCT
admet-2859	212	13	acceptor	acceptor	NOUN
admet-2859	212	14	compartment	compartment	NOUN
admet-2859	212	15	media	medium	NOUN
admet-2859	212	16	composition	composition	NOUN
admet-2859	212	17	.	.	PUNCT
admet-2859	213	1	drug	drug	NOUN
admet-2859	213	2	discovery	discovery	PROPN
admet-2859	213	3	today	today	NOUN
admet-2859	213	4	29	29	NUM
admet-2859	213	5	(	(	PUNCT
admet-2859	213	6	2024	2024	NUM
admet-2859	213	7	)	)	PUNCT
admet-2859	213	8	104214	104214	NUM
admet-2859	213	9	.	.	PUNCT
admet-2859	214	1	https://doi.org/https://doi.org/10.1016/j.drudis.2024.104214	https://doi.org/https://doi.org/10.1016/j.drudis.2024.104214	X
admet-2859	214	2	[	[	X
admet-2859	214	3	3	3	X
admet-2859	214	4	]	]	X
admet-2859	214	5	f.l	f.l	PROPN
admet-2859	214	6	.	.	PROPN
admet-2859	214	7	holzem	holzem	PROPN
admet-2859	214	8	,	,	PUNCT
admet-2859	214	9	i.h	i.h	PROPN
admet-2859	214	10	.	.	PROPN
admet-2859	214	11	jensen	jensen	PROPN
admet-2859	214	12	,	,	PUNCT
admet-2859	214	13	j.	j.	PROPN
admet-2859	214	14	petrig	petrig	PROPN
admet-2859	214	15	schaffland	schaffland	PROPN
admet-2859	214	16	,	,	PUNCT
admet-2859	214	17	c.	c.	PROPN
admet-2859	214	18	stillhart	stillhart	PROPN
admet-2859	214	19	,	,	PUNCT
admet-2859	214	20	m.	m.	PROPN
admet-2859	214	21	brandl	brandl	PROPN
admet-2859	214	22	,	,	PUNCT
admet-2859	214	23	a.	a.	PROPN
admet-2859	214	24	bauer	bauer	PROPN
admet-2859	214	25	-	-	PUNCT
admet-2859	214	26	brandl	brandl	PROPN
admet-2859	214	27	.	.	PUNCT
admet-2859	215	1	combining	combine	VERB
admet-2859	215	2	in	in	ADP
admet-2859	215	3	vitro	vitro	X
admet-2859	215	4	dissolution	dissolution	NOUN
admet-2859	215	5	/	/	SYM
admet-2859	215	6	permeation	permeation	NOUN
admet-2859	215	7	with	with	ADP
admet-2859	215	8	microdialysis	microdialysis	NOUN
admet-2859	215	9	sampling	sampling	NOUN
admet-2859	215	10	:	:	PUNCT
admet-2859	215	11	capabilities	capability	NOUN
admet-2859	215	12	and	and	CCONJ
admet-2859	215	13	limitations	limitation	NOUN
admet-2859	215	14	for	for	ADP
admet-2859	215	15	biopharmaceutical	biopharmaceutical	ADJ
admet-2859	215	16	assessments	assessment	NOUN
admet-2859	215	17	of	of	ADP
admet-2859	215	18	supersaturating	supersaturate	VERB
admet-2859	215	19	drug	drug	NOUN
admet-2859	215	20	formulations	formulation	NOUN
admet-2859	215	21	.	.	PUNCT
admet-2859	216	1	european	european	ADJ
admet-2859	216	2	journal	journal	PROPN
admet-2859	216	3	of	of	ADP
admet-2859	216	4	pharmaceutical	pharmaceutical	PROPN
admet-2859	216	5	sciences	science	NOUN
admet-2859	216	6	188	188	NUM
admet-2859	216	7	(	(	PUNCT
admet-2859	216	8	2023	2023	NUM
admet-2859	216	9	)	)	PUNCT
admet-2859	216	10	106533	106533	NUM
admet-2859	216	11	.	.	PUNCT
admet-2859	217	1	https://doi.org/https://doi.org/10.1016/j.ejps.2023.106533	https://doi.org/https://doi.org/10.1016/j.ejps.2023.106533	X
admet-2859	218	1	[	[	X
admet-2859	218	2	4	4	NUM
admet-2859	218	3	]	]	X
admet-2859	218	4	p.d	p.d	PROPN
admet-2859	218	5	.	.	PROPN
admet-2859	218	6	nunes	nunes	PROPN
admet-2859	218	7	,	,	PUNCT
admet-2859	218	8	a.f	a.f	PROPN
admet-2859	218	9	.	.	PROPN
admet-2859	218	10	ferreira	ferreira	PROPN
admet-2859	218	11	,	,	PUNCT
admet-2859	218	12	j.f	j.f	PROPN
admet-2859	218	13	.	.	PROPN
admet-2859	218	14	pinto	pinto	PROPN
admet-2859	218	15	,	,	PUNCT
admet-2859	218	16	a.	a.	PROPN
admet-2859	218	17	bauer	bauer	PROPN
admet-2859	218	18	-	-	PUNCT
admet-2859	218	19	brandl	brandl	PROPN
admet-2859	218	20	,	,	PUNCT
admet-2859	218	21	m.	m.	NOUN
admet-2859	218	22	brandl	brandl	PROPN
admet-2859	218	23	,	,	PUNCT
admet-2859	218	24	j.	j.	PROPN
admet-2859	218	25	henriques	henriques	PROPN
admet-2859	218	26	,	,	PUNCT
admet-2859	218	27	a.m.	a.m.	PROPN
admet-2859	218	28	paiva	paiva	PROPN
admet-2859	218	29	.	.	PUNCT
admet-2859	219	1	in	in	ADP
admet-2859	219	2	vitro	vitro	X
admet-2859	219	3	dissolution	dissolution	NOUN
admet-2859	219	4	/	/	SYM
admet-2859	219	5	permeation	permeation	NOUN
admet-2859	219	6	tools	tool	NOUN
admet-2859	219	7	for	for	ADP
admet-2859	219	8	amorphous	amorphous	ADJ
admet-2859	219	9	solid	solid	ADJ
admet-2859	219	10	dispersions	dispersion	NOUN
admet-2859	219	11	bioavailability	bioavailability	NOUN
admet-2859	219	12	forecasting	forecasting	NOUN
admet-2859	219	13	ii	ii	PROPN
admet-2859	219	14	:	:	PUNCT
admet-2859	219	15	comparison	comparison	NOUN
admet-2859	219	16	and	and	CCONJ
admet-2859	219	17	mechanistic	mechanistic	ADJ
admet-2859	219	18	insights	insight	NOUN
admet-2859	219	19	.	.	PUNCT
admet-2859	220	1	european	european	ADJ
admet-2859	220	2	journal	journal	PROPN
admet-2859	220	3	of	of	ADP
admet-2859	220	4	pharmaceutical	pharmaceutical	PROPN
admet-2859	220	5	sciences	science	NOUN
admet-2859	220	6	188	188	NUM
admet-2859	220	7	(	(	PUNCT
admet-2859	220	8	2023	2023	NUM
admet-2859	220	9	)	)	PUNCT
admet-2859	220	10	106513	106513	NUM
admet-2859	220	11	.	.	PUNCT
admet-2859	221	1	https://doi.org/https://doi.org/10.1016/j.ejps.2023.106513	https://doi.org/https://doi.org/10.1016/j.ejps.2023.106513	PROPN
admet-2859	222	1	[	[	X
admet-2859	222	2	5	5	NUM
admet-2859	222	3	]	]	PUNCT
admet-2859	222	4	a.	a.	NOUN
admet-2859	222	5	cuoco	cuoco	PROPN
admet-2859	222	6	,	,	PUNCT
admet-2859	222	7	j.b	j.b	PROPN
admet-2859	222	8	.	.	PROPN
admet-2859	222	9	eriksen	eriksen	PROPN
admet-2859	222	10	,	,	PUNCT
admet-2859	222	11	b.	b.	PROPN
admet-2859	222	12	luppi	luppi	PROPN
admet-2859	222	13	,	,	PUNCT
admet-2859	222	14	m.	m.	PROPN
admet-2859	222	15	brandl	brandl	PROPN
admet-2859	222	16	,	,	PUNCT
admet-2859	222	17	a.	a.	PROPN
admet-2859	222	18	bauer	bauer	PROPN
admet-2859	222	19	-	-	PUNCT
admet-2859	222	20	brandl	brandl	PROPN
admet-2859	222	21	.	.	PUNCT
admet-2859	223	1	when	when	SCONJ
admet-2859	223	2	interactions	interaction	NOUN
admet-2859	223	3	between	between	ADP
admet-2859	223	4	bile	bile	NOUN
admet-2859	223	5	salts	salt	NOUN
admet-2859	223	6	and	and	CCONJ
admet-2859	223	7	cyclodextrin	cyclodextrin	NOUN
admet-2859	223	8	cause	cause	VERB
admet-2859	223	9	a	a	DET
admet-2859	223	10	negative	negative	ADJ
admet-2859	223	11	food	food	NOUN
admet-2859	223	12	effect	effect	NOUN
admet-2859	223	13	:	:	PUNCT
admet-2859	223	14	dynamic	dynamic	ADJ
admet-2859	223	15	dissolution	dissolution	NOUN
admet-2859	223	16	/	/	SYM
admet-2859	223	17	permeation	permeation	NOUN
admet-2859	223	18	studies	study	NOUN
admet-2859	223	19	with	with	ADP
admet-2859	223	20	itraconazole	itraconazole	NOUN
admet-2859	223	21	(	(	PUNCT
admet-2859	223	22	sporanox	sporanox	PROPN
admet-2859	223	23	®	®	PROPN
admet-2859	223	24	)	)	PUNCT
admet-2859	223	25	and	and	CCONJ
admet-2859	223	26	biomimetic	biomimetic	ADJ
admet-2859	223	27	media	medium	NOUN
admet-2859	223	28	.	.	PUNCT
admet-2859	224	1	journal	journal	NOUN
admet-2859	224	2	of	of	ADP
admet-2859	224	3	pharmaceutical	pharmaceutical	PROPN
admet-2859	224	4	sciences	science	NOUN
admet-2859	224	5	112	112	NUM
admet-2859	224	6	(	(	PUNCT
admet-2859	224	7	2023	2023	NUM
admet-2859	224	8	)	)	PUNCT
admet-2859	224	9	1372	1372	NUM
admet-2859	224	10	-	-	SYM
admet-2859	224	11	1378	1378	NUM
admet-2859	224	12	.	.	PUNCT
admet-2859	225	1	https://doi.org/https://doi.org/10.1016/j.xphs.2022.12.010	https://doi.org/https://doi.org/10.1016/j.xphs.2022.12.010	ADJ
admet-2859	226	1	[	[	X
admet-2859	226	2	6	6	NUM
admet-2859	226	3	]	]	X
admet-2859	226	4	f.l	f.l	PROPN
admet-2859	226	5	.	.	PROPN
admet-2859	226	6	holzem	holzem	PROPN
admet-2859	226	7	,	,	PUNCT
admet-2859	226	8	a.	a.	PROPN
admet-2859	226	9	weck	weck	PROPN
admet-2859	226	10	,	,	PUNCT
admet-2859	226	11	j.p	j.p	PROPN
admet-2859	226	12	.	.	PROPN
admet-2859	226	13	schaffland	schaffland	PROPN
admet-2859	226	14	,	,	PUNCT
admet-2859	226	15	c.	c.	PROPN
admet-2859	226	16	stillhart	stillhart	PROPN
admet-2859	226	17	,	,	PUNCT
admet-2859	226	18	s.	s.	PROPN
admet-2859	226	19	klein	klein	PROPN
admet-2859	226	20	,	,	PUNCT
admet-2859	226	21	a.	a.	PROPN
admet-2859	226	22	bauer	bauer	PROPN
admet-2859	226	23	-	-	PUNCT
admet-2859	226	24	brandl	brandl	PROPN
admet-2859	226	25	,	,	PUNCT
admet-2859	226	26	m.	m.	NOUN
admet-2859	226	27	brandl	brandl	PROPN
admet-2859	226	28	.	.	PUNCT
admet-2859	227	1	biopredictive	biopredictive	ADJ
admet-2859	227	2	capability	capability	NOUN
admet-2859	227	3	assessment	assessment	NOUN
admet-2859	227	4	of	of	ADP
admet-2859	227	5	two	two	NUM
admet-2859	227	6	dissolution	dissolution	ADJ
admet-2859	227	7	/	/	SYM
admet-2859	227	8	permeation	permeation	NOUN
admet-2859	227	9	assays	assay	NOUN
admet-2859	227	10	,	,	PUNCT
admet-2859	227	11	µflux	µflux	VERB
admet-2859	227	12	™	™	ADJ
admet-2859	227	13	and	and	CCONJ
admet-2859	227	14	permealoop	permealoop	NOUN
admet-2859	227	15	™	™	NOUN
admet-2859	227	16	,	,	PUNCT
admet-2859	227	17	using	use	VERB
admet-2859	227	18	supersaturating	supersaturating	NOUN
admet-2859	227	19	formulations	formulation	NOUN
admet-2859	227	20	of	of	ADP
admet-2859	227	21	posaconazole	posaconazole	NOUN
admet-2859	227	22	.	.	PUNCT
admet-2859	228	1	european	european	ADJ
admet-2859	228	2	journal	journal	PROPN
admet-2859	228	3	of	of	ADP
admet-2859	228	4	pharmaceutical	pharmaceutical	PROPN
admet-2859	228	5	sciences	science	NOUN
admet-2859	228	6	176	176	NUM
admet-2859	228	7	(	(	PUNCT
admet-2859	228	8	2022	2022	NUM
admet-2859	228	9	)	)	PUNCT
admet-2859	228	10	106260	106260	NUM
admet-2859	228	11	.	.	PUNCT
admet-2859	229	1	https://doi.org/https://doi.org/10.1016/j.ejps.2022.106260	https://doi.org/https://doi.org/10.1016/j.ejps.2022.106260	X
admet-2859	229	2	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	X
admet-2859	229	3	https://doi.org/10.5599/admet.2753	https://doi.org/10.5599/admet.2753	X
admet-2859	229	4	https://doi.org/https:/doi.org/10.1016/j.drudis.2024.104214	https://doi.org/https:/doi.org/10.1016/j.drudis.2024.104214	ADV
admet-2859	229	5	https://doi.org/https:/doi.org/10.1016/j.ejps.2023.106533	https://doi.org/https:/doi.org/10.1016/j.ejps.2023.106533	PROPN
admet-2859	229	6	https://doi.org/https:/doi.org/10.1016/j.ejps.2023.106513	https://doi.org/https:/doi.org/10.1016/j.ejps.2023.106513	PROPN
admet-2859	229	7	https://doi.org/https:/doi.org/10.1016/j.xphs.2022.12.010	https://doi.org/https:/doi.org/10.1016/j.xphs.2022.12.010	PROPN
admet-2859	229	8	https://doi.org/https:/doi.org/10.1016/j.ejps.2022.106260	https://doi.org/https:/doi.org/10.1016/j.ejps.2022.106260	PROPN
admet-2859	230	1	p.	p.	PROPN
admet-2859	230	2	tőzsér	tőzsér	PROPN
admet-2859	230	3	et	et	PROPN
admet-2859	230	4	al	al	PROPN
admet-2859	230	5	.	.	PROPN
admet-2859	230	6	admet	admet	PROPN
admet-2859	230	7	&	&	CCONJ
admet-2859	230	8	dmpk	dmpk	PROPN
admet-2859	230	9	13(5	13(5	NUM
admet-2859	230	10	)	)	PUNCT
admet-2859	230	11	(	(	PUNCT
admet-2859	230	12	2025	2025	NUM
admet-2859	230	13	)	)	PUNCT
admet-2859	230	14	2859	2859	NUM
admet-2859	230	15	12	12	NUM
admet-2859	231	1	[	[	X
admet-2859	231	2	7	7	NUM
admet-2859	231	3	]	]	PUNCT
admet-2859	231	4	k.	k.	PROPN
admet-2859	231	5	sugano	sugano	PROPN
admet-2859	231	6	.	.	PUNCT
admet-2859	232	1	introduction	introduction	NOUN
admet-2859	232	2	to	to	ADP
admet-2859	232	3	computational	computational	ADJ
admet-2859	232	4	oral	oral	ADJ
admet-2859	232	5	absorption	absorption	NOUN
admet-2859	232	6	simulation	simulation	NOUN
admet-2859	232	7	.	.	PUNCT
admet-2859	233	1	expert	expert	NOUN
admet-2859	233	2	opin	opin	NOUN
admet-2859	233	3	drug	drug	NOUN
admet-2859	233	4	metab	metab	NOUN
admet-2859	233	5	toxicol	toxicol	NOUN
admet-2859	233	6	5	5	NUM
admet-2859	233	7	(	(	PUNCT
admet-2859	233	8	2009	2009	NUM
admet-2859	233	9	)	)	PUNCT
admet-2859	233	10	259	259	NUM
admet-2859	233	11	-	-	SYM
admet-2859	233	12	293	293	NUM
admet-2859	233	13	.	.	PUNCT
admet-2859	234	1	https://doi.org/10.1517/17425250902835506	https://doi.org/10.1517/17425250902835506	X
admet-2859	235	1	[	[	X
admet-2859	235	2	8	8	NUM
admet-2859	235	3	]	]	PUNCT
admet-2859	235	4	k.	k.	PROPN
admet-2859	235	5	sugano	sugano	PROPN
admet-2859	235	6	,	,	PUNCT
admet-2859	235	7	biopharmaceutics	biopharmaceutics	NOUN
admet-2859	235	8	modeling	modeling	NOUN
admet-2859	235	9	and	and	CCONJ
admet-2859	235	10	simulations	simulation	NOUN
admet-2859	235	11	:	:	PUNCT
admet-2859	235	12	theory	theory	NOUN
admet-2859	235	13	,	,	PUNCT
admet-2859	235	14	practice	practice	NOUN
admet-2859	235	15	,	,	PUNCT
admet-2859	235	16	methods	method	NOUN
admet-2859	235	17	,	,	PUNCT
admet-2859	235	18	and	and	CCONJ
admet-2859	235	19	applications	application	NOUN
admet-2859	235	20	,	,	PUNCT
admet-2859	235	21	john	john	PROPN
admet-2859	235	22	wiley	wiley	PROPN
admet-2859	235	23	&	&	CCONJ
admet-2859	235	24	sons	son	NOUN
admet-2859	235	25	,	,	PUNCT
admet-2859	235	26	2012	2012	NUM
admet-2859	235	27	.	.	PUNCT
admet-2859	236	1	https://doi.org/https://doi.org/10.1002/9781118354339.ch7	https://doi.org/https://doi.org/10.1002/9781118354339.ch7	X
admet-2859	237	1	[	[	X
admet-2859	237	2	9	9	NUM
admet-2859	237	3	]	]	PUNCT
admet-2859	237	4	w.	w.	PROPN
admet-2859	237	5	nernst	nernst	PROPN
admet-2859	237	6	,	,	PUNCT
admet-2859	237	7	theoretical	theoretical	ADJ
admet-2859	237	8	chemistry	chemistry	NOUN
admet-2859	237	9	from	from	ADP
admet-2859	237	10	the	the	DET
admet-2859	237	11	standpoint	standpoint	NOUN
admet-2859	237	12	of	of	ADP
admet-2859	237	13	avogadro	avogadro	PROPN
admet-2859	237	14	’s	’s	PART
admet-2859	237	15	rule	rule	NOUN
admet-2859	237	16	and	and	CCONJ
admet-2859	237	17	thermodynamics	thermodynamic	NOUN
admet-2859	237	18	,	,	PUNCT
admet-2859	237	19	macmillan	macmillan	PROPN
admet-2859	237	20	and	and	CCONJ
admet-2859	237	21	co.	co.	PROPN
admet-2859	237	22	,	,	PUNCT
admet-2859	237	23	limited	limited	ADJ
admet-2859	237	24	,	,	PUNCT
admet-2859	237	25	london	london	PROPN
admet-2859	237	26	,	,	PUNCT
admet-2859	237	27	uk	uk	PROPN
admet-2859	237	28	,	,	PUNCT
admet-2859	237	29	1911	1911	NUM
admet-2859	237	30	.	.	PUNCT
admet-2859	238	1	https://archive.org/details/chemistrytheo00nernrich/page/n5/mode/2up	https://archive.org/details/chemistrytheo00nernrich/page/n5/mode/2up	PROPN
admet-2859	239	1	[	[	X
admet-2859	239	2	10	10	NUM
admet-2859	239	3	]	]	PUNCT
admet-2859	239	4	t.	t.	PROPN
admet-2859	239	5	higuchi	higuchi	PROPN
admet-2859	239	6	.	.	PUNCT
admet-2859	240	1	rate	rate	NOUN
admet-2859	240	2	of	of	ADP
admet-2859	240	3	release	release	NOUN
admet-2859	240	4	of	of	ADP
admet-2859	240	5	medicaments	medicament	NOUN
admet-2859	240	6	from	from	ADP
admet-2859	240	7	ointment	ointment	NOUN
admet-2859	240	8	bases	basis	NOUN
admet-2859	240	9	containing	contain	VERB
admet-2859	240	10	drugs	drug	NOUN
admet-2859	240	11	in	in	ADP
admet-2859	240	12	suspension	suspension	NOUN
admet-2859	240	13	.	.	PUNCT
admet-2859	241	1	journal	journal	NOUN
admet-2859	241	2	of	of	ADP
admet-2859	241	3	pharmaceutical	pharmaceutical	PROPN
admet-2859	241	4	sciences	science	NOUN
admet-2859	241	5	50	50	NUM
admet-2859	241	6	(	(	PUNCT
admet-2859	241	7	1961	1961	NUM
admet-2859	241	8	)	)	PUNCT
admet-2859	241	9	874	874	NUM
admet-2859	241	10	-	-	SYM
admet-2859	241	11	875	875	NUM
admet-2859	241	12	.	.	PUNCT
admet-2859	241	13	https://doi.org/https://doi.org/10.1002/jps.2600501018	https://doi.org/https://doi.org/10.1002/jps.2600501018	NOUN
admet-2859	242	1	[	[	X
admet-2859	242	2	11	11	NUM
admet-2859	242	3	]	]	PUNCT
admet-2859	242	4	t.	t.	PROPN
admet-2859	242	5	higuchi	higuchi	PROPN
admet-2859	242	6	.	.	PUNCT
admet-2859	243	1	mechanisms	mechanism	NOUN
admet-2859	243	2	of	of	ADP
admet-2859	243	3	sustained	sustained	ADJ
admet-2859	243	4	action	action	NOUN
admet-2859	243	5	mediation	mediation	NOUN
admet-2859	243	6	.	.	PUNCT
admet-2859	244	1	theoretical	theoretical	ADJ
admet-2859	244	2	analysis	analysis	NOUN
admet-2859	244	3	of	of	ADP
admet-2859	244	4	rate	rate	NOUN
admet-2859	244	5	of	of	ADP
admet-2859	244	6	release	release	NOUN
admet-2859	244	7	of	of	ADP
admet-2859	244	8	solid	solid	ADJ
admet-2859	244	9	drugs	drug	NOUN
admet-2859	244	10	dispersed	disperse	VERB
admet-2859	244	11	in	in	ADP
admet-2859	244	12	solid	solid	ADJ
admet-2859	244	13	matrices	matrix	NOUN
admet-2859	244	14	.	.	PUNCT
admet-2859	245	1	journal	journal	NOUN
admet-2859	245	2	of	of	ADP
admet-2859	245	3	pharmaceutical	pharmaceutical	ADJ
admet-2859	245	4	sciences	science	NOUN
admet-2859	245	5	52	52	NUM
admet-2859	245	6	(	(	PUNCT
admet-2859	245	7	1963	1963	NUM
admet-2859	245	8	)	)	PUNCT
admet-2859	245	9	1145	1145	NUM
admet-2859	245	10	-	-	SYM
admet-2859	245	11	1149	1149	NUM
admet-2859	245	12	.	.	PUNCT
admet-2859	246	1	https://doi.org/10.1002/jps.2600521210	https://doi.org/10.1002/jps.2600521210	PROPN
admet-2859	246	2	[	[	X
admet-2859	246	3	12	12	NUM
admet-2859	246	4	]	]	PUNCT
admet-2859	246	5	j.	j.	PROPN
admet-2859	246	6	siepmann	siepmann	PROPN
admet-2859	246	7	,	,	PUNCT
admet-2859	246	8	n.a	n.a	PROPN
admet-2859	246	9	.	.	PROPN
admet-2859	246	10	peppas	peppas	PROPN
admet-2859	246	11	.	.	PUNCT
admet-2859	247	1	higuchi	higuchi	ADJ
admet-2859	247	2	equation	equation	NOUN
admet-2859	247	3	:	:	PUNCT
admet-2859	247	4	derivation	derivation	NOUN
admet-2859	247	5	,	,	PUNCT
admet-2859	247	6	applications	application	NOUN
admet-2859	247	7	,	,	PUNCT
admet-2859	247	8	use	use	NOUN
admet-2859	247	9	and	and	CCONJ
admet-2859	247	10	misuse	misuse	NOUN
admet-2859	247	11	.	.	PUNCT
admet-2859	248	1	int	int	NOUN
admet-2859	248	2	j	j	PROPN
admet-2859	248	3	pharm	pharm	PROPN
admet-2859	248	4	418	418	NUM
admet-2859	248	5	(	(	PUNCT
admet-2859	248	6	2011	2011	NUM
admet-2859	248	7	)	)	PUNCT
admet-2859	248	8	6	6	NUM
admet-2859	248	9	-	-	SYM
admet-2859	248	10	12	12	NUM
admet-2859	248	11	.	.	PUNCT
admet-2859	249	1	https://doi.org/10.1016/j.ijpharm.2011.03.051	https://doi.org/10.1016/j.ijpharm.2011.03.051	PROPN
admet-2859	250	1	[	[	X
admet-2859	250	2	13	13	NUM
admet-2859	250	3	]	]	PUNCT
admet-2859	250	4	a.	a.	NOUN
admet-2859	250	5	avdeef	avdeef	PROPN
admet-2859	250	6	,	,	PUNCT
admet-2859	250	7	absorption	absorption	NOUN
admet-2859	250	8	and	and	CCONJ
admet-2859	250	9	drug	drug	NOUN
admet-2859	250	10	development	development	NOUN
admet-2859	250	11	:	:	PUNCT
admet-2859	250	12	solubility	solubility	NOUN
admet-2859	250	13	,	,	PUNCT
admet-2859	250	14	permeability	permeability	NOUN
admet-2859	250	15	,	,	PUNCT
admet-2859	250	16	and	and	CCONJ
admet-2859	250	17	charge	charge	NOUN
admet-2859	250	18	state	state	NOUN
admet-2859	250	19	;	;	PUNCT
admet-2859	250	20	2nd	2nd	ADJ
admet-2859	250	21	ed	ed	NOUN
admet-2859	250	22	,	,	PUNCT
admet-2859	250	23	john	john	PROPN
admet-2859	250	24	wiley	wiley	PROPN
admet-2859	250	25	and	and	CCONJ
admet-2859	250	26	sons	son	NOUN
admet-2859	250	27	,	,	PUNCT
admet-2859	250	28	united	united	PROPN
admet-2859	250	29	states	states	PROPN
admet-2859	250	30	.	.	PUNCT
admet-2859	251	1	https://doi.org/10.1002/9781118286067	https://doi.org/10.1002/9781118286067	PRON
admet-2859	252	1	[	[	X
admet-2859	252	2	14	14	NUM
admet-2859	252	3	]	]	PUNCT
admet-2859	252	4	m.	m.	NOUN
admet-2859	252	5	czajkowski	czajkowski	NOUN
admet-2859	252	6	,	,	PUNCT
admet-2859	252	7	a.-c	a.-c	PROPN
admet-2859	252	8	.	.	PUNCT
admet-2859	253	1	jacobsen	jacobsen	PROPN
admet-2859	253	2	,	,	PUNCT
admet-2859	253	3	a.	a.	PROPN
admet-2859	253	4	bauer	bauer	PROPN
admet-2859	253	5	-	-	PUNCT
admet-2859	253	6	brandl	brandl	PROPN
admet-2859	253	7	,	,	PUNCT
admet-2859	253	8	m.	m.	NOUN
admet-2859	253	9	brandl	brandl	PROPN
admet-2859	253	10	,	,	PUNCT
admet-2859	253	11	p.	p.	PROPN
admet-2859	253	12	skupin	skupin	PROPN
admet-2859	253	13	-	-	PUNCT
admet-2859	253	14	mrugalska	mrugalska	PROPN
admet-2859	253	15	.	.	PUNCT
admet-2859	254	1	hydrogenated	hydrogenate	VERB
admet-2859	254	2	phospholipid	phospholipid	NOUN
admet-2859	254	3	,	,	PUNCT
admet-2859	254	4	a	a	DET
admet-2859	254	5	promising	promising	ADJ
admet-2859	254	6	excipient	excipient	NOUN
admet-2859	254	7	in	in	ADP
admet-2859	254	8	amorphous	amorphous	ADJ
admet-2859	254	9	solid	solid	ADJ
admet-2859	254	10	dispersions	dispersion	NOUN
admet-2859	254	11	of	of	ADP
admet-2859	254	12	fenofibrate	fenofibrate	NOUN
admet-2859	254	13	for	for	ADP
admet-2859	254	14	oral	oral	ADJ
admet-2859	254	15	delivery	delivery	NOUN
admet-2859	254	16	:	:	PUNCT
admet-2859	254	17	preparation	preparation	NOUN
admet-2859	254	18	and	and	CCONJ
admet-2859	254	19	in	in	ADP
admet-2859	254	20	-	-	PUNCT
admet-2859	254	21	vitro	vitro	X
admet-2859	254	22	biopharmaceutical	biopharmaceutical	ADJ
admet-2859	254	23	characterization	characterization	NOUN
admet-2859	254	24	.	.	PUNCT
admet-2859	255	1	international	international	ADJ
admet-2859	255	2	journal	journal	PROPN
admet-2859	255	3	of	of	ADP
admet-2859	255	4	pharmaceutics	pharmaceutic	NOUN
admet-2859	255	5	644	644	NUM
admet-2859	255	6	(	(	PUNCT
admet-2859	255	7	2023	2023	NUM
admet-2859	255	8	)	)	PUNCT
admet-2859	255	9	123294	123294	NUM
admet-2859	255	10	.	.	PUNCT
admet-2859	256	1	https://doi.org/https://doi.org/10.1016/j.ijpharm.2023.123294	https://doi.org/https://doi.org/10.1016/j.ijpharm.2023.123294	NOUN
admet-2859	256	2	[	[	X
admet-2859	256	3	15	15	NUM
admet-2859	256	4	]	]	PUNCT
admet-2859	256	5	a.-c	a.-c	PROPN
admet-2859	256	6	.	.	PUNCT
admet-2859	257	1	jacobsen	jacobsen	PROPN
admet-2859	257	2	,	,	PUNCT
admet-2859	257	3	p.a	p.a	PROPN
admet-2859	257	4	.	.	PROPN
admet-2859	257	5	elvang	elvang	PROPN
admet-2859	257	6	,	,	PUNCT
admet-2859	257	7	a.	a.	PROPN
admet-2859	257	8	bauer	bauer	PROPN
admet-2859	257	9	-	-	PUNCT
admet-2859	257	10	brandl	brandl	PROPN
admet-2859	257	11	,	,	PUNCT
admet-2859	257	12	m.	m.	NOUN
admet-2859	257	13	brandl	brandl	PROPN
admet-2859	257	14	.	.	PUNCT
admet-2859	258	1	a	a	DET
admet-2859	258	2	dynamic	dynamic	ADJ
admet-2859	258	3	in	in	ADP
admet-2859	258	4	vitro	vitro	X
admet-2859	258	5	permeation	permeation	NOUN
admet-2859	258	6	study	study	NOUN
admet-2859	258	7	on	on	ADP
admet-2859	258	8	solid	solid	ADJ
admet-2859	258	9	monoand	monoand	NOUN
admet-2859	258	10	diacyl	diacyl	NOUN
admet-2859	258	11	-	-	PUNCT
admet-2859	258	12	phospholipid	phospholipid	NOUN
admet-2859	258	13	dispersions	dispersion	NOUN
admet-2859	258	14	of	of	ADP
admet-2859	258	15	celecoxib	celecoxib	PROPN
admet-2859	258	16	.	.	PUNCT
admet-2859	259	1	european	european	PROPN
admet-2859	259	2	journal	journal	PROPN
admet-2859	259	3	of	of	ADP
admet-2859	259	4	pharmaceutical	pharmaceutical	PROPN
admet-2859	259	5	sciences	science	NOUN
admet-2859	259	6	127	127	NUM
admet-2859	259	7	(	(	PUNCT
admet-2859	259	8	2019	2019	NUM
admet-2859	259	9	)	)	PUNCT
admet-2859	259	10	199	199	NUM
admet-2859	259	11	-	-	SYM
admet-2859	259	12	207	207	NUM
admet-2859	259	13	.	.	PUNCT
admet-2859	260	1	https://doi.org/https://doi.org/10.1016/j.ejps.2018.11.003	https://doi.org/https://doi.org/10.1016/j.ejps.2018.11.003	NOUN
admet-2859	261	1	[	[	X
admet-2859	261	2	16	16	NUM
admet-2859	261	3	]	]	PUNCT
admet-2859	261	4	s.	s.	PROPN
admet-2859	261	5	koplin	koplin	PROPN
admet-2859	261	6	,	,	PUNCT
admet-2859	261	7	m.	m.	PROPN
admet-2859	261	8	kumpugdee	kumpugdee	PROPN
admet-2859	261	9	-	-	PUNCT
admet-2859	261	10	vollrath	vollrath	PROPN
admet-2859	261	11	,	,	PUNCT
admet-2859	261	12	a.	a.	PROPN
admet-2859	261	13	bauer	bauer	PROPN
admet-2859	261	14	-	-	PUNCT
admet-2859	261	15	brandl	brandl	PROPN
admet-2859	261	16	,	,	PUNCT
admet-2859	261	17	m.	m.	NOUN
admet-2859	261	18	brandl	brandl	PROPN
admet-2859	261	19	.	.	PUNCT
admet-2859	262	1	surfactants	surfactant	NOUN
admet-2859	262	2	enhance	enhance	VERB
admet-2859	262	3	recovery	recovery	NOUN
admet-2859	262	4	of	of	ADP
admet-2859	262	5	poorly	poorly	ADV
admet-2859	262	6	soluble	soluble	ADJ
admet-2859	262	7	drugs	drug	NOUN
admet-2859	262	8	during	during	ADP
admet-2859	262	9	microdialysis	microdialysis	NOUN
admet-2859	262	10	sampling	sampling	NOUN
admet-2859	262	11	:	:	PUNCT
admet-2859	262	12	implications	implication	NOUN
admet-2859	262	13	for	for	ADP
admet-2859	262	14	in	in	ADP
admet-2859	262	15	vitro	vitro	X
admet-2859	262	16	dissolution-/permeationstudies	dissolution-/permeationstudie	NOUN
admet-2859	262	17	.	.	PUNCT
admet-2859	263	1	journal	journal	NOUN
admet-2859	263	2	of	of	ADP
admet-2859	263	3	pharmaceutical	pharmaceutical	NOUN
admet-2859	263	4	and	and	CCONJ
admet-2859	263	5	biomedical	biomedical	ADJ
admet-2859	263	6	analysis	analysis	NOUN
admet-2859	263	7	145	145	NUM
admet-2859	263	8	(	(	PUNCT
admet-2859	263	9	2017	2017	NUM
admet-2859	263	10	)	)	PUNCT
admet-2859	263	11	586	586	NUM
admet-2859	263	12	-	-	SYM
admet-2859	263	13	592	592	NUM
admet-2859	263	14	.	.	PUNCT
admet-2859	264	1	https://doi.org/https://doi.org/10.1016/j.jpba.2017.07.022	https://doi.org/https://doi.org/10.1016/j.jpba.2017.07.022	NOUN
admet-2859	264	2	[	[	X
admet-2859	264	3	17	17	NUM
admet-2859	264	4	]	]	X
admet-2859	264	5	d.	d.	PROPN
admet-2859	264	6	sironi	sironi	PROPN
admet-2859	264	7	,	,	PUNCT
admet-2859	264	8	j.	j.	PROPN
admet-2859	264	9	rosenberg	rosenberg	PROPN
admet-2859	264	10	,	,	PUNCT
admet-2859	264	11	a.	a.	PROPN
admet-2859	264	12	bauer	bauer	PROPN
admet-2859	264	13	-	-	PUNCT
admet-2859	264	14	brandl	brandl	PROPN
admet-2859	264	15	,	,	PUNCT
admet-2859	264	16	m.	m.	NOUN
admet-2859	264	17	brandl	brandl	PROPN
admet-2859	264	18	.	.	PUNCT
admet-2859	265	1	dynamic	dynamic	ADJ
admet-2859	265	2	dissolution-/permeation	dissolution-/permeation	NOUN
admet-2859	265	3	-	-	PUNCT
admet-2859	265	4	testing	testing	NOUN
admet-2859	265	5	of	of	ADP
admet-2859	265	6	nano	nano	NOUN
admet-2859	265	7	and	and	CCONJ
admet-2859	265	8	microparticle	microparticle	NOUN
admet-2859	265	9	formulations	formulation	NOUN
admet-2859	265	10	of	of	ADP
admet-2859	265	11	fenofibrate	fenofibrate	NOUN
admet-2859	265	12	.	.	PUNCT
admet-2859	266	1	european	european	PROPN
admet-2859	266	2	journal	journal	PROPN
admet-2859	266	3	of	of	ADP
admet-2859	266	4	pharmaceutical	pharmaceutical	PROPN
admet-2859	266	5	sciences	science	NOUN
admet-2859	266	6	96	96	NUM
admet-2859	266	7	(	(	PUNCT
admet-2859	266	8	2017	2017	NUM
admet-2859	266	9	)	)	PUNCT
admet-2859	266	10	20	20	NUM
admet-2859	266	11	-	-	SYM
admet-2859	266	12	27	27	NUM
admet-2859	266	13	.	.	PUNCT
admet-2859	267	1	https://doi.org/https://doi.org/10.1016/j.ejps.2016.09.001	https://doi.org/https://doi.org/10.1016/j.ejps.2016.09.001	NOUN
admet-2859	267	2	[	[	X
admet-2859	267	3	18	18	NUM
admet-2859	267	4	]	]	X
admet-2859	267	5	j.r	j.r	PROPN
admet-2859	267	6	.	.	PROPN
admet-2859	267	7	jørgensen	jørgensen	PROPN
admet-2859	267	8	,	,	PUNCT
admet-2859	267	9	w.	w.	PROPN
admet-2859	267	10	mohr	mohr	PROPN
admet-2859	267	11	,	,	PUNCT
admet-2859	267	12	m.	m.	NOUN
admet-2859	267	13	rischer	rischer	NOUN
admet-2859	267	14	,	,	PUNCT
admet-2859	267	15	a.	a.	NOUN
admet-2859	267	16	sauer	sauer	PROPN
admet-2859	267	17	,	,	PUNCT
admet-2859	267	18	s.	s.	PROPN
admet-2859	267	19	mistry	mistry	PROPN
admet-2859	267	20	,	,	PUNCT
admet-2859	267	21	t.	t.	PROPN
admet-2859	267	22	rades	rades	PROPN
admet-2859	267	23	,	,	PUNCT
admet-2859	267	24	a.	a.	NOUN
admet-2859	267	25	müllertz	müllertz	NOUN
admet-2859	267	26	.	.	PUNCT
admet-2859	268	1	in	in	ADP
admet-2859	268	2	vitro	vitro	NOUN
admet-2859	268	3	-	-	PUNCT
admet-2859	268	4	in	in	ADP
admet-2859	268	5	vivo	vivo	NOUN
admet-2859	268	6	relationship	relationship	NOUN
admet-2859	268	7	for	for	ADP
admet-2859	268	8	amorphous	amorphous	ADJ
admet-2859	268	9	solid	solid	ADJ
admet-2859	268	10	dispersions	dispersion	NOUN
admet-2859	268	11	using	use	VERB
admet-2859	268	12	a	a	DET
admet-2859	268	13	double	double	ADJ
admet-2859	268	14	membrane	membrane	NOUN
admet-2859	268	15	dissolution	dissolution	NOUN
admet-2859	268	16	-	-	PUNCT
admet-2859	268	17	permeation	permeation	NOUN
admet-2859	268	18	setup	setup	NOUN
admet-2859	268	19	.	.	PUNCT
admet-2859	269	1	european	european	ADJ
admet-2859	269	2	journal	journal	PROPN
admet-2859	269	3	of	of	ADP
admet-2859	269	4	pharmaceutics	pharmaceutic	NOUN
admet-2859	269	5	and	and	CCONJ
admet-2859	269	6	biopharmaceutics	biopharmaceutic	NOUN
admet-2859	269	7	188	188	NUM
admet-2859	269	8	(	(	PUNCT
admet-2859	269	9	2023	2023	NUM
admet-2859	269	10	)	)	PUNCT
admet-2859	269	11	26	26	NUM
admet-2859	269	12	-	-	SYM
admet-2859	269	13	32	32	NUM
admet-2859	269	14	.	.	PUNCT
admet-2859	270	1	https://doi.org/https://doi.org/10.1016/j.ejpb.2023.04.026	https://doi.org/https://doi.org/10.1016/j.ejpb.2023.04.026	PROPN
admet-2859	271	1	[	[	X
admet-2859	271	2	19	19	NUM
admet-2859	271	3	]	]	PUNCT
admet-2859	271	4	t.	t.	PROPN
admet-2859	271	5	loftsson	loftsson	PROPN
admet-2859	271	6	,	,	PUNCT
admet-2859	271	7	s.b	s.b	PROPN
admet-2859	271	8	.	.	PROPN
admet-2859	271	9	vogensen	vogensen	PROPN
admet-2859	271	10	,	,	PUNCT
admet-2859	271	11	c.	c.	PROPN
admet-2859	271	12	desbos	desbos	PROPN
admet-2859	271	13	,	,	PUNCT
admet-2859	271	14	p.	p.	NOUN
admet-2859	271	15	jansook	jansook	PROPN
admet-2859	271	16	.	.	PUNCT
admet-2859	272	1	carvedilol	carvedilol	NOUN
admet-2859	272	2	:	:	PUNCT
admet-2859	272	3	solubilization	solubilization	NOUN
admet-2859	272	4	and	and	CCONJ
admet-2859	272	5	cyclodextrin	cyclodextrin	NOUN
admet-2859	272	6	complexation	complexation	NOUN
admet-2859	272	7	:	:	PUNCT
admet-2859	272	8	a	a	DET
admet-2859	272	9	technical	technical	ADJ
admet-2859	272	10	note	note	NOUN
admet-2859	272	11	.	.	PUNCT
admet-2859	273	1	aaps	aap	NOUN
admet-2859	273	2	pharmscitech	pharmscitech	VERB
admet-2859	273	3	9	9	NUM
admet-2859	273	4	(	(	PUNCT
admet-2859	273	5	2008	2008	NUM
admet-2859	273	6	)	)	PUNCT
admet-2859	273	7	425	425	NUM
admet-2859	273	8	-	-	SYM
admet-2859	273	9	430	430	NUM
admet-2859	273	10	.	.	PUNCT
admet-2859	274	1	https://doi.org/10.1208/s12249-008-9055-7	https://doi.org/10.1208/s12249-008-9055-7	NUM
admet-2859	275	1	[	[	X
admet-2859	275	2	20	20	NUM
admet-2859	275	3	]	]	PUNCT
admet-2859	275	4	t.	t.	PROPN
admet-2859	275	5	loftsson	loftsson	NOUN
admet-2859	275	6	.	.	PUNCT
admet-2859	276	1	cyclodextrins	cyclodextrin	NOUN
admet-2859	276	2	in	in	ADP
admet-2859	276	3	parenteral	parenteral	ADJ
admet-2859	276	4	formulations	formulation	NOUN
admet-2859	276	5	.	.	PUNCT
admet-2859	277	1	journal	journal	PROPN
admet-2859	277	2	of	of	ADP
admet-2859	277	3	pharmaceutical	pharmaceutical	PROPN
admet-2859	277	4	sciences	science	NOUN
admet-2859	277	5	110	110	NUM
admet-2859	277	6	(	(	PUNCT
admet-2859	277	7	2021	2021	NUM
admet-2859	277	8	)	)	PUNCT
admet-2859	277	9	654	654	NUM
admet-2859	277	10	-	-	PUNCT
admet-2859	277	11	664	664	NUM
admet-2859	277	12	.	.	PUNCT
admet-2859	278	1	https://doi.org/10.1016/j.xphs.2020.10.026	https://doi.org/10.1016/j.xphs.2020.10.026	PROPN
admet-2859	279	1	[	[	X
admet-2859	279	2	21	21	NUM
admet-2859	279	3	]	]	X
admet-2859	279	4	s.	s.	PROPN
admet-2859	279	5	sripetch	sripetch	PROPN
admet-2859	279	6	,	,	PUNCT
admet-2859	279	7	m.	m.	PROPN
admet-2859	279	8	prajapati	prajapati	PROPN
admet-2859	279	9	,	,	PUNCT
admet-2859	279	10	t.	t.	PROPN
admet-2859	279	11	loftsson	loftsson	NOUN
admet-2859	279	12	.	.	PUNCT
admet-2859	280	1	cyclodextrins	cyclodextrin	NOUN
admet-2859	280	2	and	and	CCONJ
admet-2859	280	3	drug	drug	NOUN
admet-2859	280	4	membrane	membrane	NOUN
admet-2859	280	5	permeation	permeation	NOUN
admet-2859	280	6	:	:	PUNCT
admet-2859	280	7	thermodynamic	thermodynamic	ADJ
admet-2859	280	8	considerations	consideration	NOUN
admet-2859	280	9	.	.	PUNCT
admet-2859	281	1	journal	journal	NOUN
admet-2859	281	2	of	of	ADP
admet-2859	281	3	pharmaceutical	pharmaceutical	PROPN
admet-2859	281	4	sciences	science	NOUN
admet-2859	281	5	111	111	NUM
admet-2859	281	6	(	(	PUNCT
admet-2859	281	7	2022	2022	NUM
admet-2859	281	8	)	)	PUNCT
admet-2859	281	9	2571	2571	NUM
admet-2859	281	10	-	-	SYM
admet-2859	281	11	2580	2580	NUM
admet-2859	281	12	.	.	PUNCT
admet-2859	282	1	https://doi.org/https://doi.org/10.1016/j.xphs.2022.04.015	https://doi.org/https://doi.org/10.1016/j.xphs.2022.04.015	NOUN
admet-2859	282	2	[	[	X
admet-2859	282	3	22	22	NUM
admet-2859	282	4	]	]	PUNCT
admet-2859	282	5	p.	p.	PROPN
admet-2859	282	6	berben	berben	PROPN
admet-2859	282	7	,	,	PUNCT
admet-2859	282	8	e.	e.	PROPN
admet-2859	282	9	borbás	borbás	PROPN
admet-2859	282	10	,	,	PUNCT
admet-2859	282	11	intestinal	intestinal	ADJ
admet-2859	282	12	drug	drug	NOUN
admet-2859	282	13	absorption	absorption	NOUN
admet-2859	282	14	:	:	PUNCT
admet-2859	282	15	cell	cell	NOUN
admet-2859	282	16	-	-	PUNCT
admet-2859	282	17	free	free	ADJ
admet-2859	282	18	permeation	permeation	NOUN
admet-2859	282	19	systems	system	NOUN
admet-2859	282	20	,	,	PUNCT
admet-2859	282	21	in	in	ADP
admet-2859	282	22	drug	drug	NOUN
admet-2859	282	23	discovery	discovery	NOUN
admet-2859	282	24	and	and	CCONJ
admet-2859	282	25	evaluation	evaluation	NOUN
admet-2859	282	26	:	:	PUNCT
admet-2859	282	27	safety	safety	NOUN
admet-2859	282	28	and	and	CCONJ
admet-2859	282	29	pharmacokinetic	pharmacokinetic	ADJ
admet-2859	282	30	assays	assay	NOUN
admet-2859	282	31	,	,	PUNCT
admet-2859	282	32	f.j	f.j	PROPN
admet-2859	282	33	.	.	PROPN
admet-2859	282	34	hock	hock	NOUN
admet-2859	282	35	,	,	PUNCT
admet-2859	282	36	m.r	m.r	PROPN
admet-2859	282	37	.	.	PROPN
admet-2859	282	38	gralinski	gralinski	PROPN
admet-2859	282	39	,	,	PUNCT
admet-2859	282	40	m.k	m.k	PROPN
admet-2859	282	41	.	.	PROPN
admet-2859	282	42	pugsley	pugsley	PROPN
admet-2859	282	43	(	(	PUNCT
admet-2859	282	44	eds	eds	PROPN
admet-2859	282	45	.	.	PUNCT
admet-2859	282	46	)	)	PUNCT
admet-2859	282	47	,	,	PUNCT
admet-2859	282	48	springer	springer	NOUN
admet-2859	282	49	international	international	ADJ
admet-2859	282	50	publishing	publishing	NOUN
admet-2859	282	51	,	,	PUNCT
admet-2859	282	52	cham	cham	NOUN
admet-2859	282	53	,	,	PUNCT
admet-2859	282	54	2022	2022	NUM
admet-2859	282	55	,	,	PUNCT
admet-2859	282	56	p.	p.	NOUN
admet-2859	282	57	1	1	NUM
admet-2859	282	58	-	-	SYM
admet-2859	282	59	29	29	NUM
admet-2859	282	60	.	.	PUNCT
admet-2859	283	1	https://doi.org/10.1007/978-3-030-73317-9_95-1	https://doi.org/10.1007/978-3-030-73317-9_95-1	PUNCT
admet-2859	284	1	[	[	X
admet-2859	284	2	23	23	NUM
admet-2859	284	3	]	]	X
admet-2859	284	4	e.	e.	PROPN
admet-2859	284	5	borbás	borbás	PROPN
admet-2859	284	6	,	,	PUNCT
admet-2859	284	7	a.	a.	PROPN
admet-2859	284	8	balogh	balogh	PROPN
admet-2859	284	9	,	,	PUNCT
admet-2859	284	10	k.	k.	PROPN
admet-2859	284	11	bocz	bocz	PROPN
admet-2859	284	12	,	,	PUNCT
admet-2859	284	13	j.	j.	PROPN
admet-2859	284	14	müller	müller	PROPN
admet-2859	284	15	,	,	PUNCT
admet-2859	284	16	é	é	PROPN
admet-2859	284	17	.	.	PUNCT
admet-2859	284	18	kiserdei	kiserdei	PROPN
admet-2859	284	19	,	,	PUNCT
admet-2859	284	20	t.	t.	PROPN
admet-2859	284	21	vigh	vigh	PROPN
admet-2859	284	22	,	,	PUNCT
admet-2859	284	23	b.	b.	PROPN
admet-2859	284	24	sinkó	sinkó	PROPN
admet-2859	284	25	,	,	PUNCT
admet-2859	284	26	a.	a.	NOUN
admet-2859	284	27	marosi	marosi	PROPN
admet-2859	284	28	,	,	PUNCT
admet-2859	284	29	a.	a.	NOUN
admet-2859	284	30	halász	halász	PROPN
admet-2859	284	31	,	,	PUNCT
admet-2859	284	32	z.	z.	PROPN
admet-2859	284	33	dohányos	dohányos	PROPN
admet-2859	284	34	,	,	PUNCT
admet-2859	284	35	l.	l.	NOUN
admet-2859	284	36	szente	szente	PROPN
admet-2859	284	37	,	,	PUNCT
admet-2859	284	38	g.t	g.t	PROPN
admet-2859	284	39	.	.	PROPN
admet-2859	284	40	balogh	balogh	PROPN
admet-2859	284	41	,	,	PUNCT
admet-2859	284	42	z.k	z.k	PROPN
admet-2859	284	43	.	.	PROPN
admet-2859	284	44	nagy	nagy	PROPN
admet-2859	284	45	.	.	PUNCT
admet-2859	285	1	in	in	ADP
admet-2859	285	2	vitro	vitro	X
admet-2859	285	3	dissolution	dissolution	NOUN
admet-2859	285	4	-	-	PUNCT
admet-2859	285	5	permeation	permeation	NOUN
admet-2859	285	6	evaluation	evaluation	NOUN
admet-2859	285	7	of	of	ADP
admet-2859	285	8	an	an	DET
admet-2859	285	9	electrospun	electrospun	NOUN
admet-2859	285	10	cyclodextrin	cyclodextrin	NOUN
admet-2859	285	11	-	-	PUNCT
admet-2859	285	12	based	base	VERB
admet-2859	285	13	formulation	formulation	NOUN
admet-2859	285	14	of	of	ADP
admet-2859	285	15	aripiprazole	aripiprazole	NOUN
admet-2859	285	16	using	use	VERB
admet-2859	285	17	μflux	μflux	NOUN
admet-2859	285	18	™	™	NOUN
admet-2859	285	19	.	.	PUNCT
admet-2859	286	1	international	international	ADJ
admet-2859	286	2	journal	journal	PROPN
admet-2859	286	3	of	of	ADP
admet-2859	286	4	pharmaceutics	pharmaceutic	NOUN
admet-2859	286	5	491	491	NUM
admet-2859	286	6	(	(	PUNCT
admet-2859	286	7	2015	2015	NUM
admet-2859	286	8	)	)	PUNCT
admet-2859	286	9	180	180	NUM
admet-2859	286	10	-	-	SYM
admet-2859	286	11	189	189	NUM
admet-2859	286	12	.	.	PUNCT
admet-2859	287	1	https://doi.org/10.1016/j.ijpharm.2015.06.019	https://doi.org/10.1016/j.ijpharm.2015.06.019	PROPN
admet-2859	287	2	[	[	X
admet-2859	287	3	24	24	NUM
admet-2859	287	4	]	]	X
admet-2859	287	5	[	[	X
admet-2859	287	6	24	24	NUM
admet-2859	287	7	]	]	PUNCT
admet-2859	287	8	a.	a.	NOUN
admet-2859	287	9	avdeef	avdeef	PROPN
admet-2859	287	10	,	,	PUNCT
admet-2859	287	11	m.	m.	PROPN
admet-2859	287	12	strafford	strafford	PROPN
admet-2859	287	13	,	,	PUNCT
admet-2859	287	14	e.	e.	PROPN
admet-2859	287	15	block	block	PROPN
admet-2859	287	16	,	,	PUNCT
admet-2859	287	17	m.p	m.p	PROPN
admet-2859	287	18	.	.	PROPN
admet-2859	287	19	balogh	balogh	PROPN
admet-2859	287	20	,	,	PUNCT
admet-2859	287	21	w.	w.	PROPN
admet-2859	287	22	chambliss	chambliss	PROPN
admet-2859	287	23	,	,	PUNCT
admet-2859	287	24	i.	i.	PROPN
admet-2859	287	25	khan	khan	PROPN
admet-2859	287	26	.	.	PUNCT
admet-2859	288	1	drug	drug	NOUN
admet-2859	288	2	absorption	absorption	NOUN
admet-2859	288	3	in	in	ADP
admet-2859	288	4	vitro	vitro	X
admet-2859	288	5	model	model	NOUN
admet-2859	288	6	:	:	PUNCT
admet-2859	288	7	filter	filter	NOUN
admet-2859	288	8	-	-	PUNCT
admet-2859	288	9	immobilized	immobilized	ADJ
admet-2859	288	10	artificial	artificial	ADJ
admet-2859	288	11	membranes	membrane	NOUN
admet-2859	288	12	.	.	PUNCT
admet-2859	289	1	2	2	X
admet-2859	289	2	.	.	X
admet-2859	289	3	studies	study	NOUN
admet-2859	289	4	of	of	ADP
admet-2859	289	5	the	the	DET
admet-2859	289	6	permeability	permeability	NOUN
admet-2859	289	7	properties	property	NOUN
admet-2859	289	8	of	of	ADP
admet-2859	289	9	lactones	lactone	NOUN
admet-2859	289	10	in	in	ADP
admet-2859	289	11	piper	piper	NOUN
admet-2859	289	12	methysticum	methysticum	PROPN
admet-2859	289	13	forst	forst	PROPN
admet-2859	289	14	.	.	PUNCT
admet-2859	290	1	eur	eur	PROPN
admet-2859	290	2	j	j	PROPN
admet-2859	290	3	pharm	pharm	PROPN
admet-2859	290	4	sci	sci	PROPN
admet-2859	290	5	14	14	NUM
admet-2859	290	6	(	(	PUNCT
admet-2859	290	7	2001	2001	NUM
admet-2859	290	8	)	)	PUNCT
admet-2859	290	9	271	271	NUM
admet-2859	290	10	-	-	SYM
admet-2859	290	11	280	280	NUM
admet-2859	290	12	.	.	PUNCT
admet-2859	290	13	https://doi.org/10.1016/s09280987(01)00191-9	https://doi.org/10.1016/s09280987(01)00191-9	VERB
admet-2859	290	14	https://doi.org/10.1517/17425250902835506	https://doi.org/10.1517/17425250902835506	NOUN
admet-2859	290	15	https://doi.org/https:/doi.org/10.1002/9781118354339.ch7	https://doi.org/https:/doi.org/10.1002/9781118354339.ch7	PROPN
admet-2859	290	16	https://archive.org/details/chemistrytheo00nernrich/page/n5/mode/2up	https://archive.org/details/chemistrytheo00nernrich/page/n5/mode/2up	PROPN
admet-2859	290	17	https://doi.org/https:/doi.org/10.1002/jps.2600501018	https://doi.org/https:/doi.org/10.1002/jps.2600501018	INTJ
admet-2859	290	18	https://doi.org/10.1002/jps.2600521210	https://doi.org/10.1002/jps.2600521210	PROPN
admet-2859	290	19	https://doi.org/10.1016/j.ijpharm.2011.03.051	https://doi.org/10.1016/j.ijpharm.2011.03.051	PROPN
admet-2859	291	1	https://doi.org/10.1002/9781118286067	https://doi.org/10.1002/9781118286067	NOUN
admet-2859	291	2	https://doi.org/https:/doi.org/10.1016/j.ijpharm.2023.123294	https://doi.org/https:/doi.org/10.1016/j.ijpharm.2023.123294	NOUN
admet-2859	291	3	https://doi.org/https:/doi.org/10.1016/j.ejps.2018.11.003	https://doi.org/https:/doi.org/10.1016/j.ejps.2018.11.003	PROPN
admet-2859	291	4	https://doi.org/https:/doi.org/10.1016/j.jpba.2017.07.022	https://doi.org/https:/doi.org/10.1016/j.jpba.2017.07.022	PROPN
admet-2859	291	5	https://doi.org/https:/doi.org/10.1016/j.ejps.2016.09.001	https://doi.org/https:/doi.org/10.1016/j.ejps.2016.09.001	PROPN
admet-2859	291	6	https://doi.org/https:/doi.org/10.1016/j.ejpb.2023.04.026	https://doi.org/https:/doi.org/10.1016/j.ejpb.2023.04.026	PROPN
admet-2859	291	7	https://doi.org/10.1208/s12249-008-9055-7	https://doi.org/10.1208/s12249-008-9055-7	NUM
admet-2859	291	8	https://doi.org/10.1016/j.xphs.2020.10.026	https://doi.org/10.1016/j.xphs.2020.10.026	PROPN
admet-2859	292	1	https://doi.org/https:/doi.org/10.1016/j.xphs.2022.04.015	https://doi.org/https:/doi.org/10.1016/j.xphs.2022.04.015	ADJ
admet-2859	292	2	https://doi.org/10.1007/978-3-030-73317-9_95-1	https://doi.org/10.1007/978-3-030-73317-9_95-1	PROPN
admet-2859	292	3	https://doi.org/10.1016/j.ijpharm.2015.06.019	https://doi.org/10.1016/j.ijpharm.2015.06.019	AUX
admet-2859	292	4	https://doi.org/10.1016/s0928-0987(01)00191-9	https://doi.org/10.1016/s0928-0987(01)00191-9	VERB
admet-2859	292	5	https://doi.org/10.1016/s0928-0987(01)00191-9	https://doi.org/10.1016/s0928-0987(01)00191-9	X
admet-2859	292	6	admet	admet	PROPN
admet-2859	292	7	&	&	CCONJ
admet-2859	292	8	dmpk	dmpk	PROPN
admet-2859	292	9	13(5	13(5	NOUN
admet-2859	292	10	)	)	PUNCT
admet-2859	292	11	(	(	PUNCT
admet-2859	292	12	2025	2025	NUM
admet-2859	292	13	)	)	PUNCT
admet-2859	292	14	2859	2859	NUM
admet-2859	292	15	comparison	comparison	NOUN
admet-2859	292	16	of	of	ADP
admet-2859	292	17	lipophilic	lipophilic	ADJ
admet-2859	292	18	and	and	CCONJ
admet-2859	292	19	size	size	NOUN
admet-2859	292	20	-	-	PUNCT
admet-2859	292	21	exclusion	exclusion	NOUN
admet-2859	292	22	membranes	membrane	NOUN
admet-2859	292	23	doi	doi	NOUN
admet-2859	292	24	:	:	PUNCT
admet-2859	292	25	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	X
admet-2859	292	26	13	13	NUM
admet-2859	293	1	[	[	X
admet-2859	293	2	25	25	NUM
admet-2859	293	3	]	]	X
admet-2859	293	4	[	[	X
admet-2859	293	5	25	25	NUM
admet-2859	293	6	]	]	PUNCT
admet-2859	293	7	b.	b.	PROPN
admet-2859	293	8	sinkó	sinkó	PROPN
admet-2859	293	9	,	,	PUNCT
admet-2859	293	10	t.m	t.m	PROPN
admet-2859	293	11	.	.	PROPN
admet-2859	293	12	garrigues	garrigues	PROPN
admet-2859	293	13	,	,	PUNCT
admet-2859	293	14	g.t	g.t	PROPN
admet-2859	293	15	.	.	PROPN
admet-2859	293	16	balogh	balogh	PROPN
admet-2859	293	17	,	,	PUNCT
admet-2859	293	18	z.k	z.k	PROPN
admet-2859	293	19	.	.	PROPN
admet-2859	293	20	nagy	nagy	PROPN
admet-2859	293	21	,	,	PUNCT
admet-2859	293	22	o.	o.	PROPN
admet-2859	293	23	tsinman	tsinman	NOUN
admet-2859	293	24	,	,	PUNCT
admet-2859	293	25	a.	a.	PROPN
admet-2859	293	26	avdeef	avdeef	PROPN
admet-2859	293	27	,	,	PUNCT
admet-2859	293	28	k.	k.	PROPN
admet-2859	293	29	takács	takács	PROPN
admet-2859	293	30	-	-	PUNCT
admet-2859	293	31	novák	novák	PROPN
admet-2859	293	32	.	.	PROPN
admet-2859	293	33	skinpampa	skinpampa	PROPN
admet-2859	293	34	:	:	PUNCT
admet-2859	293	35	a	a	DET
admet-2859	293	36	new	new	ADJ
admet-2859	293	37	method	method	NOUN
admet-2859	293	38	for	for	ADP
admet-2859	293	39	fast	fast	ADJ
admet-2859	293	40	prediction	prediction	NOUN
admet-2859	293	41	of	of	ADP
admet-2859	293	42	skin	skin	NOUN
admet-2859	293	43	penetration	penetration	NOUN
admet-2859	293	44	.	.	PUNCT
admet-2859	294	1	european	european	PROPN
admet-2859	294	2	journal	journal	PROPN
admet-2859	294	3	of	of	ADP
admet-2859	294	4	pharmaceutical	pharmaceutical	PROPN
admet-2859	294	5	sciences	science	NOUN
admet-2859	294	6	45	45	NUM
admet-2859	294	7	(	(	PUNCT
admet-2859	294	8	2012	2012	NUM
admet-2859	294	9	)	)	PUNCT
admet-2859	294	10	698	698	NUM
admet-2859	294	11	-	-	SYM
admet-2859	294	12	707	707	NUM
admet-2859	294	13	.	.	PUNCT
admet-2859	295	1	https://doi.org/10.1016/j.ejps.2012.01.011	https://doi.org/10.1016/j.ejps.2012.01.011	NOUN
admet-2859	295	2	[	[	X
admet-2859	295	3	26	26	NUM
admet-2859	295	4	]	]	X
admet-2859	295	5	g.e	g.e	PROPN
admet-2859	295	6	.	.	PROPN
admet-2859	295	7	flaten	flaten	PROPN
admet-2859	295	8	,	,	PUNCT
admet-2859	295	9	a.b	a.b	PROPN
admet-2859	295	10	.	.	NOUN
admet-2859	295	11	dhanikula	dhanikula	PROPN
admet-2859	295	12	,	,	PUNCT
admet-2859	295	13	k.	k.	PROPN
admet-2859	295	14	luthman	luthman	PROPN
admet-2859	295	15	,	,	PUNCT
admet-2859	295	16	m.	m.	NOUN
admet-2859	295	17	brandl	brandl	PROPN
admet-2859	295	18	.	.	PUNCT
admet-2859	296	1	drug	drug	NOUN
admet-2859	296	2	permeability	permeability	NOUN
admet-2859	296	3	across	across	ADP
admet-2859	296	4	a	a	DET
admet-2859	296	5	phospholipid	phospholipid	NOUN
admet-2859	296	6	vesicle	vesicle	NOUN
admet-2859	296	7	based	base	VERB
admet-2859	296	8	barrier	barrier	NOUN
admet-2859	296	9	:	:	PUNCT
admet-2859	296	10	a	a	DET
admet-2859	296	11	novel	novel	ADJ
admet-2859	296	12	approach	approach	NOUN
admet-2859	296	13	for	for	ADP
admet-2859	296	14	studying	study	VERB
admet-2859	296	15	passive	passive	ADJ
admet-2859	296	16	diffusion	diffusion	NOUN
admet-2859	296	17	.	.	PUNCT
admet-2859	297	1	european	european	PROPN
admet-2859	297	2	journal	journal	PROPN
admet-2859	297	3	of	of	ADP
admet-2859	297	4	pharmaceutical	pharmaceutical	PROPN
admet-2859	297	5	sciences	science	NOUN
admet-2859	297	6	27	27	NUM
admet-2859	297	7	(	(	PUNCT
admet-2859	297	8	2006	2006	NUM
admet-2859	297	9	)	)	PUNCT
admet-2859	297	10	80	80	NUM
admet-2859	297	11	-	-	SYM
admet-2859	297	12	90	90	NUM
admet-2859	297	13	.	.	PUNCT
admet-2859	298	1	https://doi.org/10.1016/j.ejps.2005.08.007	https://doi.org/10.1016/j.ejps.2005.08.007	NOUN
admet-2859	298	2	[	[	X
admet-2859	298	3	27	27	NUM
admet-2859	298	4	]	]	PUNCT
admet-2859	298	5	m.	m.	NOUN
admet-2859	298	6	di	di	X
admet-2859	298	7	cagno	cagno	PROPN
admet-2859	298	8	,	,	PUNCT
admet-2859	298	9	h.a	h.a	PROPN
admet-2859	298	10	.	.	PROPN
admet-2859	298	11	bibi	bibi	PROPN
admet-2859	298	12	,	,	PUNCT
admet-2859	298	13	a.	a.	PROPN
admet-2859	298	14	bauer	bauer	PROPN
admet-2859	298	15	-	-	PUNCT
admet-2859	298	16	brandl	brandl	PROPN
admet-2859	298	17	.	.	PUNCT
admet-2859	299	1	new	new	ADJ
admet-2859	299	2	biomimetic	biomimetic	ADJ
admet-2859	299	3	barrier	barrier	NOUN
admet-2859	299	4	permeapad	permeapad	NOUN
admet-2859	299	5	™	™	NOUN
admet-2859	299	6	for	for	ADP
admet-2859	299	7	efficient	efficient	ADJ
admet-2859	299	8	investigation	investigation	NOUN
admet-2859	299	9	of	of	ADP
admet-2859	299	10	passive	passive	ADJ
admet-2859	299	11	permeability	permeability	NOUN
admet-2859	299	12	of	of	ADP
admet-2859	299	13	drugs	drug	NOUN
admet-2859	299	14	.	.	PUNCT
admet-2859	300	1	european	european	ADJ
admet-2859	300	2	journal	journal	PROPN
admet-2859	300	3	of	of	ADP
admet-2859	300	4	pharmaceutical	pharmaceutical	PROPN
admet-2859	300	5	sciences	science	NOUN
admet-2859	300	6	73	73	NUM
admet-2859	300	7	(	(	PUNCT
admet-2859	300	8	2015	2015	NUM
admet-2859	300	9	)	)	PUNCT
admet-2859	300	10	29	29	NUM
admet-2859	300	11	-	-	SYM
admet-2859	300	12	34	34	NUM
admet-2859	300	13	.	.	PUNCT
admet-2859	301	1	https://doi.org/10.1016/j.ejps.2015.03.019	https://doi.org/10.1016/j.ejps.2015.03.019	PROPN
admet-2859	302	1	[	[	X
admet-2859	302	2	28	28	NUM
admet-2859	302	3	]	]	PUNCT
admet-2859	302	4	a.	a.	NOUN
admet-2859	302	5	avdeef	avdeef	PROPN
admet-2859	302	6	.	.	PUNCT
admet-2859	303	1	the	the	DET
admet-2859	303	2	rise	rise	NOUN
admet-2859	303	3	of	of	ADP
admet-2859	303	4	pampa	pampa	NOUN
admet-2859	303	5	.	.	PUNCT
admet-2859	304	1	expert	expert	NOUN
admet-2859	304	2	opin	opin	NOUN
admet-2859	304	3	drug	drug	NOUN
admet-2859	304	4	metab	metab	NOUN
admet-2859	304	5	toxicol	toxicol	NOUN
admet-2859	304	6	1	1	NUM
admet-2859	304	7	(	(	PUNCT
admet-2859	304	8	2005	2005	NUM
admet-2859	304	9	)	)	PUNCT
admet-2859	304	10	325	325	NUM
admet-2859	304	11	-	-	SYM
admet-2859	304	12	342	342	NUM
admet-2859	304	13	.	.	PUNCT
admet-2859	305	1	https://doi.org/10.1517/17425255.1.2.325	https://doi.org/10.1517/17425255.1.2.325	NOUN
admet-2859	306	1	[	[	X
admet-2859	306	2	29	29	NUM
admet-2859	306	3	]	]	X
admet-2859	306	4	b.	b.	PROPN
admet-2859	306	5	faller	faller	PROPN
admet-2859	306	6	.	.	PUNCT
admet-2859	307	1	artificial	artificial	ADJ
admet-2859	307	2	membrane	membrane	NOUN
admet-2859	307	3	assays	assay	NOUN
admet-2859	307	4	to	to	PART
admet-2859	307	5	assess	assess	VERB
admet-2859	307	6	permeability	permeability	NOUN
admet-2859	307	7	.	.	PUNCT
admet-2859	308	1	current	current	ADJ
admet-2859	308	2	drug	drug	NOUN
admet-2859	308	3	metabolism	metabolism	NOUN
admet-2859	308	4	9	9	NUM
admet-2859	308	5	(	(	PUNCT
admet-2859	308	6	2008	2008	NUM
admet-2859	308	7	)	)	PUNCT
admet-2859	308	8	886892	886892	NUM
admet-2859	308	9	.	.	PUNCT
admet-2859	309	1	https://doi.org/10.2174/138920008786485227	https://doi.org/10.2174/138920008786485227	X
admet-2859	310	1	[	[	X
admet-2859	310	2	30	30	NUM
admet-2859	310	3	]	]	X
admet-2859	310	4	m.	m.	NOUN
admet-2859	310	5	kansy	kansy	PROPN
admet-2859	310	6	,	,	PUNCT
admet-2859	310	7	f.	f.	PROPN
admet-2859	310	8	senner	senner	PROPN
admet-2859	310	9	,	,	PUNCT
admet-2859	310	10	k.	k.	PROPN
admet-2859	310	11	gubernator	gubernator	PROPN
admet-2859	310	12	.	.	PUNCT
admet-2859	311	1	physicochemical	physicochemical	ADJ
admet-2859	311	2	high	high	ADJ
admet-2859	311	3	throughput	throughput	NOUN
admet-2859	311	4	screening	screening	NOUN
admet-2859	311	5	:	:	PUNCT
admet-2859	311	6	parallel	parallel	ADJ
admet-2859	311	7	artificial	artificial	ADJ
admet-2859	311	8	membrane	membrane	NOUN
admet-2859	311	9	permeation	permeation	NOUN
admet-2859	311	10	assay	assay	VERB
admet-2859	311	11	in	in	ADP
admet-2859	311	12	the	the	DET
admet-2859	311	13	description	description	NOUN
admet-2859	311	14	of	of	ADP
admet-2859	311	15	passive	passive	ADJ
admet-2859	311	16	absorption	absorption	NOUN
admet-2859	311	17	processes	process	NOUN
admet-2859	311	18	.	.	PUNCT
admet-2859	312	1	journal	journal	NOUN
admet-2859	312	2	of	of	ADP
admet-2859	312	3	medicinal	medicinal	ADJ
admet-2859	312	4	chemistry	chemistry	NOUN
admet-2859	312	5	41	41	NUM
admet-2859	312	6	(	(	PUNCT
admet-2859	312	7	1998	1998	NUM
admet-2859	312	8	)	)	PUNCT
admet-2859	312	9	1007	1007	NUM
admet-2859	312	10	-	-	SYM
admet-2859	312	11	1010	1010	NUM
admet-2859	312	12	.	.	PUNCT
admet-2859	313	1	https://doi.org/10.1021/jm970530e	https://doi.org/10.1021/jm970530e	PROPN
admet-2859	314	1	[	[	X
admet-2859	314	2	31	31	NUM
admet-2859	314	3	]	]	PUNCT
admet-2859	314	4	p.	p.	PROPN
admet-2859	314	5	berben	berben	PROPN
admet-2859	314	6	,	,	PUNCT
admet-2859	314	7	a.	a.	PROPN
admet-2859	314	8	bauer	bauer	PROPN
admet-2859	314	9	-	-	PUNCT
admet-2859	314	10	brandl	brandl	PROPN
admet-2859	314	11	,	,	PUNCT
admet-2859	314	12	m.	m.	NOUN
admet-2859	314	13	brandl	brandl	PROPN
admet-2859	314	14	,	,	PUNCT
admet-2859	314	15	b.	b.	PROPN
admet-2859	314	16	faller	faller	PROPN
admet-2859	314	17	,	,	PUNCT
admet-2859	314	18	g.e	g.e	PROPN
admet-2859	314	19	.	.	PROPN
admet-2859	314	20	flaten	flaten	PROPN
admet-2859	314	21	,	,	PUNCT
admet-2859	314	22	a.-c	a.-c	PROPN
admet-2859	314	23	.	.	PUNCT
admet-2859	315	1	jacobsen	jacobsen	PROPN
admet-2859	315	2	,	,	PUNCT
admet-2859	315	3	j.	j.	PROPN
admet-2859	315	4	brouwers	brouwers	PROPN
admet-2859	315	5	,	,	PUNCT
admet-2859	315	6	p.	p.	NOUN
admet-2859	315	7	augustijns	augustijns	NOUN
admet-2859	315	8	.	.	PUNCT
admet-2859	316	1	drug	drug	NOUN
admet-2859	316	2	permeability	permeability	NOUN
admet-2859	316	3	profiling	profiling	NOUN
admet-2859	316	4	using	use	VERB
admet-2859	316	5	cell	cell	NOUN
admet-2859	316	6	-	-	PUNCT
admet-2859	316	7	free	free	ADJ
admet-2859	316	8	permeation	permeation	NOUN
admet-2859	316	9	tools	tool	NOUN
admet-2859	316	10	:	:	PUNCT
admet-2859	316	11	overview	overview	NOUN
admet-2859	316	12	and	and	CCONJ
admet-2859	316	13	applications	application	NOUN
admet-2859	316	14	.	.	PUNCT
admet-2859	317	1	european	european	ADJ
admet-2859	317	2	journal	journal	PROPN
admet-2859	317	3	of	of	ADP
admet-2859	317	4	pharmaceutical	pharmaceutical	PROPN
admet-2859	317	5	sciences	science	NOUN
admet-2859	317	6	119	119	NUM
admet-2859	317	7	(	(	PUNCT
admet-2859	317	8	2018	2018	NUM
admet-2859	317	9	)	)	PUNCT
admet-2859	317	10	219	219	NUM
admet-2859	317	11	-	-	SYM
admet-2859	317	12	233	233	NUM
admet-2859	317	13	.	.	PUNCT
admet-2859	318	1	https://doi.org/https://doi.org/10.1016/j.ejps.2018.04.016	https://doi.org/https://doi.org/10.1016/j.ejps.2018.04.016	PROPN
admet-2859	319	1	[	[	X
admet-2859	319	2	32	32	NUM
admet-2859	319	3	]	]	PUNCT
admet-2859	319	4	a.	a.	NOUN
admet-2859	319	5	adhikari	adhikari	PROPN
admet-2859	319	6	,	,	PUNCT
admet-2859	319	7	p.r	p.r	PROPN
admet-2859	319	8	.	.	PROPN
admet-2859	319	9	seo	seo	PROPN
admet-2859	319	10	,	,	PUNCT
admet-2859	319	11	j.e	j.e	PROPN
admet-2859	319	12	.	.	PROPN
admet-2859	319	13	polli	polli	PROPN
admet-2859	319	14	.	.	PUNCT
admet-2859	320	1	characterization	characterization	NOUN
admet-2859	320	2	of	of	ADP
admet-2859	320	3	dissolution	dissolution	NOUN
admet-2859	320	4	-	-	PUNCT
admet-2859	320	5	permeation	permeation	NOUN
admet-2859	320	6	system	system	NOUN
admet-2859	320	7	using	use	VERB
admet-2859	320	8	hollow	hollow	ADJ
admet-2859	320	9	fiber	fiber	NOUN
admet-2859	320	10	membrane	membrane	NOUN
admet-2859	320	11	module	module	NOUN
admet-2859	320	12	and	and	CCONJ
admet-2859	320	13	utility	utility	NOUN
admet-2859	320	14	to	to	PART
admet-2859	320	15	predict	predict	VERB
admet-2859	320	16	in	in	ADP
admet-2859	320	17	vivo	vivo	ADJ
admet-2859	320	18	drug	drug	NOUN
admet-2859	320	19	permeation	permeation	NOUN
admet-2859	320	20	across	across	ADP
admet-2859	320	21	bcs	bcs	NOUN
admet-2859	320	22	classes	class	NOUN
admet-2859	320	23	.	.	PUNCT
admet-2859	321	1	journal	journal	NOUN
admet-2859	321	2	of	of	ADP
admet-2859	321	3	pharmaceutical	pharmaceutical	PROPN
admet-2859	321	4	sciences	science	NOUN
admet-2859	321	5	111	111	NUM
admet-2859	321	6	(	(	PUNCT
admet-2859	321	7	2022	2022	NUM
admet-2859	321	8	)	)	PUNCT
admet-2859	321	9	3075	3075	NUM
admet-2859	321	10	-	-	SYM
admet-2859	321	11	3087	3087	NUM
admet-2859	321	12	.	.	PUNCT
admet-2859	322	1	https://doi.org/10.1016/j.xphs.2022.07.002	https://doi.org/10.1016/j.xphs.2022.07.002	NOUN
admet-2859	322	2	[	[	X
admet-2859	322	3	33	33	NUM
admet-2859	322	4	]	]	X
admet-2859	322	5	j.p	j.p	PROPN
admet-2859	322	6	.	.	PROPN
admet-2859	322	7	o'shea	o'shea	PROPN
admet-2859	322	8	,	,	PUNCT
admet-2859	322	9	p.	p.	NOUN
admet-2859	322	10	augustijns	augustijns	NOUN
admet-2859	322	11	,	,	PUNCT
admet-2859	322	12	m.	m.	NOUN
admet-2859	322	13	brandl	brandl	PROPN
admet-2859	322	14	,	,	PUNCT
admet-2859	322	15	d.j	d.j	PROPN
admet-2859	322	16	.	.	PROPN
admet-2859	322	17	brayden	brayden	PROPN
admet-2859	322	18	,	,	PUNCT
admet-2859	322	19	j.	j.	PROPN
admet-2859	322	20	brouwers	brouwers	PROPN
admet-2859	322	21	,	,	PUNCT
admet-2859	322	22	b.t	b.t	PROPN
admet-2859	322	23	.	.	PROPN
admet-2859	322	24	griffin	griffin	PROPN
admet-2859	322	25	,	,	PUNCT
admet-2859	322	26	r.	r.	PROPN
admet-2859	322	27	holm	holm	PROPN
admet-2859	322	28	,	,	PUNCT
admet-2859	322	29	a.c	a.c	PROPN
admet-2859	322	30	.	.	PROPN
admet-2859	322	31	jacobsen	jacobsen	PROPN
admet-2859	322	32	,	,	PUNCT
admet-2859	322	33	h.	h.	PROPN
admet-2859	322	34	lennernäs	lennernäs	PROPN
admet-2859	322	35	,	,	PUNCT
admet-2859	322	36	z.	z.	PROPN
admet-2859	322	37	vinarov	vinarov	PROPN
admet-2859	322	38	,	,	PUNCT
admet-2859	322	39	c.m	c.m	PROPN
admet-2859	322	40	.	.	PROPN
admet-2859	322	41	o'driscoll	o'driscoll	PROPN
admet-2859	322	42	.	.	PUNCT
admet-2859	323	1	best	good	ADJ
admet-2859	323	2	practices	practice	NOUN
admet-2859	323	3	in	in	ADP
admet-2859	323	4	current	current	ADJ
admet-2859	323	5	models	model	NOUN
admet-2859	323	6	mimicking	mimic	VERB
admet-2859	323	7	drug	drug	NOUN
admet-2859	323	8	permeability	permeability	NOUN
admet-2859	323	9	in	in	ADP
admet-2859	323	10	the	the	DET
admet-2859	323	11	gastrointestinal	gastrointestinal	ADJ
admet-2859	323	12	tract	tract	NOUN
admet-2859	323	13	an	an	DET
admet-2859	323	14	ungap	ungap	NOUN
admet-2859	323	15	review	review	NOUN
admet-2859	323	16	.	.	PUNCT
admet-2859	324	1	european	european	PROPN
admet-2859	324	2	journal	journal	PROPN
admet-2859	324	3	of	of	ADP
admet-2859	324	4	pharmaceutical	pharmaceutical	PROPN
admet-2859	324	5	sciences	science	NOUN
admet-2859	324	6	170	170	NUM
admet-2859	324	7	(	(	PUNCT
admet-2859	324	8	2022	2022	NUM
admet-2859	324	9	)	)	PUNCT
admet-2859	324	10	106098	106098	NUM
admet-2859	324	11	.	.	PUNCT
admet-2859	325	1	https://doi.org/10.1016/j.ejps.2021.106098	https://doi.org/10.1016/j.ejps.2021.106098	PROPN
admet-2859	325	2	[	[	X
admet-2859	325	3	34	34	NUM
admet-2859	325	4	]	]	X
admet-2859	325	5	e.	e.	PROPN
admet-2859	325	6	borbás	borbás	PROPN
admet-2859	325	7	,	,	PUNCT
admet-2859	325	8	p.	p.	PROPN
admet-2859	325	9	tőzsér	tőzsér	PROPN
admet-2859	325	10	,	,	PUNCT
admet-2859	325	11	k.	k.	PROPN
admet-2859	325	12	tsinman	tsinman	PROPN
admet-2859	325	13	,	,	PUNCT
admet-2859	325	14	o.	o.	PROPN
admet-2859	325	15	tsinman	tsinman	PROPN
admet-2859	325	16	,	,	PUNCT
admet-2859	325	17	k.	k.	PROPN
admet-2859	325	18	takács	takács	PROPN
admet-2859	325	19	-	-	PUNCT
admet-2859	325	20	novák	novák	PROPN
admet-2859	325	21	,	,	PUNCT
admet-2859	325	22	g.	g.	PROPN
admet-2859	325	23	völgyi	völgyi	PROPN
admet-2859	325	24	,	,	PUNCT
admet-2859	325	25	b.	b.	PROPN
admet-2859	325	26	sinkó	sinkó	PROPN
admet-2859	325	27	,	,	PUNCT
admet-2859	325	28	z.k	z.k	PROPN
admet-2859	325	29	.	.	PROPN
admet-2859	325	30	nagy	nagy	PROPN
admet-2859	325	31	.	.	PUNCT
admet-2859	326	1	effect	effect	NOUN
admet-2859	326	2	of	of	ADP
admet-2859	326	3	formulation	formulation	NOUN
admet-2859	326	4	additives	additive	NOUN
admet-2859	326	5	on	on	ADP
admet-2859	326	6	drug	drug	NOUN
admet-2859	326	7	transport	transport	NOUN
admet-2859	326	8	through	through	ADP
admet-2859	326	9	size	size	NOUN
admet-2859	326	10	-	-	PUNCT
admet-2859	326	11	exclusion	exclusion	NOUN
admet-2859	326	12	membranes	membrane	NOUN
admet-2859	326	13	.	.	PUNCT
admet-2859	327	1	molecular	molecular	ADJ
admet-2859	327	2	pharmaceutics	pharmaceutic	NOUN
admet-2859	327	3	15	15	NUM
admet-2859	327	4	(	(	PUNCT
admet-2859	327	5	2018	2018	NUM
admet-2859	327	6	)	)	PUNCT
admet-2859	327	7	3308	3308	NUM
admet-2859	327	8	-	-	SYM
admet-2859	327	9	3317	3317	NUM
admet-2859	327	10	.	.	PUNCT
admet-2859	328	1	https://doi.org/10.1021/acs.molpharmaceut.8b00343	https://doi.org/10.1021/acs.molpharmaceut.8b00343	NOUN
admet-2859	329	1	[	[	X
admet-2859	329	2	35	35	NUM
admet-2859	329	3	]	]	X
admet-2859	329	4	p.	p.	PROPN
admet-2859	329	5	berben	berben	PROPN
admet-2859	329	6	,	,	PUNCT
admet-2859	329	7	j.	j.	PROPN
admet-2859	329	8	brouwers	brouwers	PROPN
admet-2859	329	9	,	,	PUNCT
admet-2859	329	10	p.	p.	NOUN
admet-2859	329	11	augustijns	augustijns	NOUN
admet-2859	329	12	.	.	PUNCT
admet-2859	330	1	the	the	DET
admet-2859	330	2	artificial	artificial	ADJ
admet-2859	330	3	membrane	membrane	NOUN
admet-2859	330	4	insert	insert	NOUN
admet-2859	330	5	system	system	NOUN
admet-2859	330	6	as	as	ADP
admet-2859	330	7	predictive	predictive	ADJ
admet-2859	330	8	tool	tool	NOUN
admet-2859	330	9	for	for	ADP
admet-2859	330	10	formulation	formulation	NOUN
admet-2859	330	11	performance	performance	NOUN
admet-2859	330	12	evaluation	evaluation	NOUN
admet-2859	330	13	.	.	PUNCT
admet-2859	331	1	international	international	ADJ
admet-2859	331	2	journal	journal	PROPN
admet-2859	331	3	of	of	ADP
admet-2859	331	4	pharmaceutics	pharmaceutic	NOUN
admet-2859	331	5	537	537	NUM
admet-2859	331	6	(	(	PUNCT
admet-2859	331	7	2018	2018	NUM
admet-2859	331	8	)	)	PUNCT
admet-2859	331	9	22	22	NUM
admet-2859	331	10	-	-	SYM
admet-2859	331	11	29	29	NUM
admet-2859	331	12	.	.	PUNCT
admet-2859	332	1	https://doi.org/https://doi.org/10.1016/j.ijpharm.2017.12.025	https://doi.org/https://doi.org/10.1016/j.ijpharm.2017.12.025	NOUN
admet-2859	333	1	[	[	X
admet-2859	333	2	36	36	NUM
admet-2859	333	3	]	]	X
admet-2859	334	1	[	[	X
admet-2859	334	2	36	36	NUM
admet-2859	334	3	]	]	X
admet-2859	334	4	p.	p.	PROPN
admet-2859	334	5	berben	berben	PROPN
admet-2859	334	6	,	,	PUNCT
admet-2859	334	7	j.	j.	PROPN
admet-2859	334	8	brouwers	brouwers	PROPN
admet-2859	334	9	,	,	PUNCT
admet-2859	334	10	p.	p.	NOUN
admet-2859	334	11	augustijns	augustijns	NOUN
admet-2859	334	12	.	.	PUNCT
admet-2859	335	1	assessment	assessment	NOUN
admet-2859	335	2	of	of	ADP
admet-2859	335	3	passive	passive	ADJ
admet-2859	335	4	intestinal	intestinal	ADJ
admet-2859	335	5	permeability	permeability	NOUN
admet-2859	335	6	using	use	VERB
admet-2859	335	7	an	an	DET
admet-2859	335	8	artificial	artificial	ADJ
admet-2859	335	9	membrane	membrane	NOUN
admet-2859	335	10	insert	insert	NOUN
admet-2859	335	11	system	system	NOUN
admet-2859	335	12	.	.	PUNCT
admet-2859	336	1	journal	journal	PROPN
admet-2859	336	2	of	of	ADP
admet-2859	336	3	pharmaceutical	pharmaceutical	PROPN
admet-2859	336	4	sciences	science	NOUN
admet-2859	336	5	107	107	NUM
admet-2859	336	6	(	(	PUNCT
admet-2859	336	7	2018	2018	NUM
admet-2859	336	8	)	)	PUNCT
admet-2859	336	9	250	250	NUM
admet-2859	336	10	-	-	SYM
admet-2859	336	11	256	256	NUM
admet-2859	336	12	.	.	PUNCT
admet-2859	337	1	https://doi.org/10.1016/j.xphs.2017.08.002	https://doi.org/10.1016/j.xphs.2017.08.002	NOUN
admet-2859	338	1	[	[	X
admet-2859	338	2	37	37	NUM
admet-2859	338	3	]	]	X
admet-2859	338	4	c.	c.	PROPN
admet-2859	338	5	washington	washington	PROPN
admet-2859	338	6	.	.	PUNCT
admet-2859	339	1	drug	drug	NOUN
admet-2859	339	2	release	release	NOUN
admet-2859	339	3	from	from	ADP
admet-2859	339	4	microdisperse	microdisperse	ADJ
admet-2859	339	5	systems	system	NOUN
admet-2859	339	6	:	:	PUNCT
admet-2859	339	7	a	a	DET
admet-2859	339	8	critical	critical	ADJ
admet-2859	339	9	review	review	NOUN
admet-2859	339	10	.	.	PUNCT
admet-2859	340	1	international	international	ADJ
admet-2859	340	2	journal	journal	PROPN
admet-2859	340	3	of	of	ADP
admet-2859	340	4	pharmaceutics	pharmaceutic	NOUN
admet-2859	340	5	58	58	NUM
admet-2859	340	6	(	(	PUNCT
admet-2859	340	7	1990	1990	NUM
admet-2859	340	8	)	)	PUNCT
admet-2859	340	9	1	1	NUM
admet-2859	340	10	-	-	SYM
admet-2859	340	11	12	12	NUM
admet-2859	340	12	.	.	PUNCT
admet-2859	341	1	https://doi.org/10.1016/0378-5173(90)90280-h	https://doi.org/10.1016/0378-5173(90)90280-h	PROPN
admet-2859	342	1	[	[	X
admet-2859	342	2	38	38	NUM
admet-2859	342	3	]	]	PUNCT
admet-2859	342	4	p.	p.	NOUN
admet-2859	342	5	saokham	saokham	PROPN
admet-2859	342	6	,	,	PUNCT
admet-2859	342	7	a.	a.	PROPN
admet-2859	342	8	sá	sá	PROPN
admet-2859	342	9	couto	couto	PROPN
admet-2859	342	10	,	,	PUNCT
admet-2859	342	11	a.	a.	PROPN
admet-2859	342	12	ryzhakov	ryzhakov	PROPN
admet-2859	342	13	,	,	PUNCT
admet-2859	342	14	t.	t.	PROPN
admet-2859	342	15	loftsson	loftsson	NOUN
admet-2859	342	16	.	.	PUNCT
admet-2859	343	1	the	the	DET
admet-2859	343	2	self	self	NOUN
admet-2859	343	3	-	-	PUNCT
admet-2859	343	4	assemble	assemble	NOUN
admet-2859	343	5	of	of	ADP
admet-2859	343	6	natural	natural	ADJ
admet-2859	343	7	cyclodextrins	cyclodextrin	NOUN
admet-2859	343	8	in	in	ADP
admet-2859	343	9	aqueous	aqueous	ADJ
admet-2859	343	10	solutions	solution	NOUN
admet-2859	343	11	:	:	PUNCT
admet-2859	343	12	application	application	NOUN
admet-2859	343	13	of	of	ADP
admet-2859	343	14	miniature	miniature	ADJ
admet-2859	343	15	permeation	permeation	NOUN
admet-2859	343	16	studies	study	NOUN
admet-2859	343	17	for	for	ADP
admet-2859	343	18	critical	critical	ADJ
admet-2859	343	19	aggregation	aggregation	NOUN
admet-2859	343	20	concentration	concentration	NOUN
admet-2859	343	21	(	(	PUNCT
admet-2859	343	22	cac	cac	PROPN
admet-2859	343	23	)	)	PUNCT
admet-2859	343	24	determinations	determination	NOUN
admet-2859	343	25	.	.	PUNCT
admet-2859	344	1	international	international	ADJ
admet-2859	344	2	journal	journal	PROPN
admet-2859	344	3	of	of	ADP
admet-2859	344	4	pharmaceutics	pharmaceutic	NOUN
admet-2859	344	5	505	505	NUM
admet-2859	344	6	(	(	PUNCT
admet-2859	344	7	2016	2016	NUM
admet-2859	344	8	)	)	PUNCT
admet-2859	344	9	187	187	NUM
admet-2859	344	10	-	-	SYM
admet-2859	344	11	193	193	NUM
admet-2859	344	12	.	.	PUNCT
admet-2859	345	1	https://doi.org/10.1016/j.ijpharm.2016.03.049	https://doi.org/10.1016/j.ijpharm.2016.03.049	PROPN
admet-2859	345	2	[	[	X
admet-2859	345	3	39	39	NUM
admet-2859	345	4	]	]	PUNCT
admet-2859	345	5	j.	j.	PROPN
admet-2859	345	6	bouayed	bouaye	VERB
admet-2859	345	7	,	,	PUNCT
admet-2859	345	8	l.	l.	PROPN
admet-2859	345	9	hoffmann	hoffmann	PROPN
admet-2859	345	10	,	,	PUNCT
admet-2859	345	11	t.	t.	PROPN
admet-2859	345	12	bohn	bohn	PROPN
admet-2859	345	13	.	.	PUNCT
admet-2859	346	1	total	total	ADJ
admet-2859	346	2	phenolics	phenolic	NOUN
admet-2859	346	3	,	,	PUNCT
admet-2859	346	4	flavonoids	flavonoid	NOUN
admet-2859	346	5	,	,	PUNCT
admet-2859	346	6	anthocyanins	anthocyanin	NOUN
admet-2859	346	7	and	and	CCONJ
admet-2859	346	8	antioxidant	antioxidant	ADJ
admet-2859	346	9	activity	activity	NOUN
admet-2859	346	10	following	follow	VERB
admet-2859	346	11	simulated	simulate	VERB
admet-2859	346	12	gastro	gastro	NOUN
admet-2859	346	13	-	-	PUNCT
admet-2859	346	14	intestinal	intestinal	ADJ
admet-2859	346	15	digestion	digestion	NOUN
admet-2859	346	16	and	and	CCONJ
admet-2859	346	17	dialysis	dialysis	NOUN
admet-2859	346	18	of	of	ADP
admet-2859	346	19	apple	apple	NOUN
admet-2859	346	20	varieties	variety	NOUN
admet-2859	346	21	:	:	PUNCT
admet-2859	346	22	bioaccessibility	bioaccessibility	NOUN
admet-2859	346	23	and	and	CCONJ
admet-2859	346	24	potential	potential	ADJ
admet-2859	346	25	uptake	uptake	NOUN
admet-2859	346	26	.	.	PUNCT
admet-2859	347	1	food	food	NOUN
admet-2859	347	2	chemistry	chemistry	NOUN
admet-2859	347	3	128	128	NUM
admet-2859	347	4	(	(	PUNCT
admet-2859	347	5	2011	2011	NUM
admet-2859	347	6	)	)	PUNCT
admet-2859	347	7	14	14	NUM
admet-2859	347	8	-	-	SYM
admet-2859	347	9	21	21	NUM
admet-2859	347	10	.	.	PUNCT
admet-2859	348	1	https://doi.org/10.1016/j.foodchem.2011.02.052	https://doi.org/10.1016/j.foodchem.2011.02.052	PRON
admet-2859	349	1	[	[	X
admet-2859	349	2	40	40	NUM
admet-2859	349	3	]	]	X
admet-2859	349	4	s.a	s.a	PROPN
admet-2859	349	5	.	.	PROPN
admet-2859	349	6	raina	raina	PROPN
admet-2859	349	7	,	,	PUNCT
admet-2859	349	8	g.g	g.g	PROPN
admet-2859	349	9	.	.	PROPN
admet-2859	349	10	zhang	zhang	PROPN
admet-2859	349	11	,	,	PUNCT
admet-2859	349	12	d.e	d.e	PROPN
admet-2859	349	13	.	.	PROPN
admet-2859	349	14	alonzo	alonzo	PROPN
admet-2859	349	15	,	,	PUNCT
admet-2859	349	16	j.	j.	PROPN
admet-2859	349	17	wu	wu	PROPN
admet-2859	349	18	,	,	PUNCT
admet-2859	349	19	d.	d.	PROPN
admet-2859	349	20	zhu	zhu	PROPN
admet-2859	349	21	,	,	PUNCT
admet-2859	349	22	n.d	n.d	PROPN
admet-2859	349	23	.	.	PROPN
admet-2859	349	24	catron	catron	PROPN
admet-2859	349	25	,	,	PUNCT
admet-2859	349	26	y.	y.	PROPN
admet-2859	349	27	gao	gao	PROPN
admet-2859	349	28	,	,	PUNCT
admet-2859	349	29	l.s	l.s	PROPN
admet-2859	349	30	.	.	PROPN
admet-2859	349	31	taylor	taylor	PROPN
admet-2859	349	32	.	.	PUNCT
admet-2859	350	1	impact	impact	NOUN
admet-2859	350	2	of	of	ADP
admet-2859	350	3	solubilizing	solubilize	VERB
admet-2859	350	4	additives	additive	NOUN
admet-2859	350	5	on	on	ADP
admet-2859	350	6	supersaturation	supersaturation	NOUN
admet-2859	350	7	and	and	CCONJ
admet-2859	350	8	membrane	membrane	NOUN
admet-2859	350	9	transport	transport	NOUN
admet-2859	350	10	of	of	ADP
admet-2859	350	11	drugs	drug	NOUN
admet-2859	350	12	.	.	PUNCT
admet-2859	351	1	pharmaceutical	pharmaceutical	ADJ
admet-2859	351	2	research	research	NOUN
admet-2859	351	3	32	32	NUM
admet-2859	351	4	(	(	PUNCT
admet-2859	351	5	2015	2015	NUM
admet-2859	351	6	)	)	PUNCT
admet-2859	351	7	3350	3350	NUM
admet-2859	351	8	-	-	SYM
admet-2859	351	9	3364	3364	NUM
admet-2859	351	10	.	.	PUNCT
admet-2859	352	1	https://doi.org/10.1007/s11095-015-1712-4	https://doi.org/10.1007/s11095-015-1712-4	NUM
admet-2859	353	1	[	[	X
admet-2859	353	2	41	41	NUM
admet-2859	353	3	]	]	X
admet-2859	353	4	a.s	a.s	PROPN
admet-2859	353	5	.	.	PROPN
admet-2859	353	6	indulkar	indulkar	PROPN
admet-2859	353	7	,	,	PUNCT
admet-2859	353	8	y.	y.	PROPN
admet-2859	353	9	gao	gao	PROPN
admet-2859	353	10	,	,	PUNCT
admet-2859	353	11	s.a	s.a	PROPN
admet-2859	353	12	.	.	PROPN
admet-2859	353	13	raina	raina	PROPN
admet-2859	353	14	,	,	PUNCT
admet-2859	353	15	g.g	g.g	PROPN
admet-2859	353	16	.	.	PROPN
admet-2859	353	17	zhang	zhang	PROPN
admet-2859	353	18	,	,	PUNCT
admet-2859	353	19	l.s	l.s	PROPN
admet-2859	353	20	.	.	PROPN
admet-2859	353	21	taylor	taylor	PROPN
admet-2859	353	22	.	.	PUNCT
admet-2859	354	1	exploiting	exploit	VERB
admet-2859	354	2	the	the	DET
admet-2859	354	3	phenomenon	phenomenon	NOUN
admet-2859	354	4	of	of	ADP
admet-2859	354	5	liquid	liquid	NOUN
admet-2859	354	6	-	-	PUNCT
admet-2859	354	7	liquid	liquid	ADJ
admet-2859	354	8	phase	phase	NOUN
admet-2859	354	9	separation	separation	NOUN
admet-2859	354	10	for	for	ADP
admet-2859	354	11	enhanced	enhanced	ADJ
admet-2859	354	12	and	and	CCONJ
admet-2859	354	13	sustained	sustained	ADJ
admet-2859	354	14	membrane	membrane	NOUN
admet-2859	354	15	transport	transport	NOUN
admet-2859	354	16	of	of	ADP
admet-2859	354	17	a	a	DET
admet-2859	354	18	poorly	poorly	ADV
admet-2859	354	19	water	water	NOUN
admet-2859	354	20	-	-	PUNCT
admet-2859	354	21	soluble	soluble	ADJ
admet-2859	354	22	drug	drug	NOUN
admet-2859	354	23	.	.	PUNCT
admet-2859	355	1	molecular	molecular	ADJ
admet-2859	355	2	pharmaceutics	pharmaceutic	NOUN
admet-2859	355	3	13	13	NUM
admet-2859	355	4	(	(	PUNCT
admet-2859	355	5	2016	2016	NUM
admet-2859	355	6	)	)	PUNCT
admet-2859	355	7	2059	2059	NUM
admet-2859	355	8	-	-	SYM
admet-2859	355	9	2069	2069	NUM
admet-2859	355	10	.	.	PUNCT
admet-2859	356	1	https://doi.org/10.1021/acs.molpharmaceut.6b00202	https://doi.org/10.1021/acs.molpharmaceut.6b00202	PROPN
admet-2859	357	1	[	[	X
admet-2859	357	2	42	42	NUM
admet-2859	357	3	]	]	X
admet-2859	357	4	g.	g.	PROPN
admet-2859	357	5	caron	caron	PROPN
admet-2859	357	6	,	,	PUNCT
admet-2859	357	7	g.	g.	PROPN
admet-2859	357	8	steyaert	steyaert	PROPN
admet-2859	357	9	,	,	PUNCT
admet-2859	357	10	a.	a.	PROPN
admet-2859	357	11	pagliara	pagliara	PROPN
admet-2859	357	12	,	,	PUNCT
admet-2859	357	13	f.	f.	PROPN
admet-2859	357	14	reymond	reymond	PROPN
admet-2859	357	15	,	,	PUNCT
admet-2859	357	16	p.	p.	NOUN
admet-2859	357	17	crivori	crivori	NOUN
admet-2859	357	18	,	,	PUNCT
admet-2859	357	19	p.	p.	PROPN
admet-2859	357	20	gaillard	gaillard	PROPN
admet-2859	357	21	,	,	PUNCT
admet-2859	357	22	p.a	p.a	PROPN
admet-2859	357	23	.	.	PROPN
admet-2859	357	24	carrupt	carrupt	PROPN
admet-2859	357	25	,	,	PUNCT
admet-2859	357	26	a.	a.	PROPN
admet-2859	357	27	ardeef	ardeef	PROPN
admet-2859	357	28	,	,	PUNCT
admet-2859	357	29	j.	j.	PROPN
admet-2859	357	30	comer	comer	PROPN
admet-2859	357	31	,	,	PUNCT
admet-2859	357	32	k.j	k.j	PROPN
admet-2859	357	33	.	.	PROPN
admet-2859	357	34	box	box	PROPN
admet-2859	357	35	,	,	PUNCT
admet-2859	357	36	h.h	h.h	PROPN
admet-2859	357	37	.	.	PROPN
admet-2859	357	38	girault	girault	PROPN
admet-2859	357	39	,	,	PUNCT
admet-2859	357	40	b.	b.	PROPN
admet-2859	357	41	testa	testa	PROPN
admet-2859	357	42	.	.	PUNCT
admet-2859	358	1	structure	structure	NOUN
admet-2859	358	2	-	-	PUNCT
admet-2859	358	3	lipophilicity	lipophilicity	NOUN
admet-2859	358	4	relationships	relationship	NOUN
admet-2859	358	5	of	of	ADP
admet-2859	358	6	neutral	neutral	ADJ
admet-2859	358	7	and	and	CCONJ
admet-2859	358	8	protonated	protonated	ADJ
admet-2859	358	9	βblockers	βblocker	NOUN
admet-2859	358	10	,	,	PUNCT
admet-2859	358	11	part	part	NOUN
admet-2859	358	12	i	i	NOUN
admet-2859	358	13	,	,	PUNCT
admet-2859	358	14	intraand	intraand	X
admet-2859	358	15	intermolecular	intermolecular	ADJ
admet-2859	358	16	effects	effect	NOUN
admet-2859	358	17	in	in	ADP
admet-2859	358	18	isotropic	isotropic	ADJ
admet-2859	358	19	solvent	solvent	NOUN
admet-2859	358	20	systems	system	NOUN
admet-2859	358	21	.	.	PUNCT
admet-2859	359	1	wiley	wiley	PROPN
admet-2859	359	2	-	-	PUNCT
admet-2859	359	3	vhca	vhca	PROPN
admet-2859	359	4	ag	ag	PROPN
admet-2859	359	5	,	,	PUNCT
admet-2859	359	6	1999	1999	NUM
admet-2859	359	7	,	,	PUNCT
admet-2859	359	8	https://doi.org/10.5599/admet.2859	https://doi.org/10.5599/admet.2859	NOUN
admet-2859	360	1	https://doi.org/10.1016/j.ejps.2012.01.011	https://doi.org/10.1016/j.ejps.2012.01.011	NOUN
admet-2859	360	2	https://doi.org/10.1016/j.ejps.2005.08.007	https://doi.org/10.1016/j.ejps.2005.08.007	NOUN
admet-2859	360	3	https://doi.org/10.1016/j.ejps.2015.03.019	https://doi.org/10.1016/j.ejps.2015.03.019	VERB
admet-2859	360	4	https://doi.org/10.1517/17425255.1.2.325	https://doi.org/10.1517/17425255.1.2.325	NOUN
admet-2859	360	5	https://doi.org/10.2174/138920008786485227	https://doi.org/10.2174/138920008786485227	PROPN
admet-2859	360	6	https://doi.org/10.1021/jm970530e	https://doi.org/10.1021/jm970530e	ADJ
admet-2859	360	7	https://doi.org/https:/doi.org/10.1016/j.ejps.2018.04.016	https://doi.org/https:/doi.org/10.1016/j.ejps.2018.04.016	PROPN
admet-2859	360	8	https://doi.org/10.1016/j.xphs.2022.07.002	https://doi.org/10.1016/j.xphs.2022.07.002	PROPN
admet-2859	360	9	https://doi.org/10.1016/j.ejps.2021.106098	https://doi.org/10.1016/j.ejps.2021.106098	PROPN
admet-2859	360	10	https://doi.org/10.1021/acs.molpharmaceut.8b00343	https://doi.org/10.1021/acs.molpharmaceut.8b00343	NOUN
admet-2859	360	11	https://doi.org/https:/doi.org/10.1016/j.ijpharm.2017.12.025	https://doi.org/https:/doi.org/10.1016/j.ijpharm.2017.12.025	ADJ
admet-2859	360	12	https://doi.org/10.1016/j.xphs.2017.08.002	https://doi.org/10.1016/j.xphs.2017.08.002	NOUN
admet-2859	360	13	https://doi.org/10.1016/0378-5173(90)90280-h	https://doi.org/10.1016/0378-5173(90)90280-h	PROPN
admet-2859	360	14	https://doi.org/10.1016/j.ijpharm.2016.03.049	https://doi.org/10.1016/j.ijpharm.2016.03.049	PROPN
admet-2859	360	15	https://doi.org/10.1016/j.foodchem.2011.02.052	https://doi.org/10.1016/j.foodchem.2011.02.052	NUM
admet-2859	360	16	https://doi.org/10.1007/s11095-015-1712-4	https://doi.org/10.1007/s11095-015-1712-4	NUM
admet-2859	360	17	https://doi.org/10.1021/acs.molpharmaceut.6b00202	https://doi.org/10.1021/acs.molpharmaceut.6b00202	PROPN
admet-2859	360	18	p.	p.	PROPN
admet-2859	360	19	tőzsér	tőzsér	PROPN
admet-2859	360	20	et	et	PROPN
admet-2859	360	21	al	al	PROPN
admet-2859	360	22	.	.	PROPN
admet-2859	360	23	admet	admet	PROPN
admet-2859	360	24	&	&	CCONJ
admet-2859	360	25	dmpk	dmpk	PROPN
admet-2859	360	26	13(5	13(5	NUM
admet-2859	360	27	)	)	PUNCT
admet-2859	360	28	(	(	PUNCT
admet-2859	360	29	2025	2025	NUM
admet-2859	360	30	)	)	PUNCT
admet-2859	360	31	2859	2859	NUM
admet-2859	360	32	14	14	NUM
admet-2859	360	33	pp	pp	NOUN
admet-2859	360	34	.	.	PUNCT
admet-2859	361	1	1211	1211	NUM
admet-2859	361	2	-	-	SYM
admet-2859	361	3	1222	1222	NUM
admet-2859	361	4	.	.	PUNCT
admet-2859	362	1	https://doi.org/10.1002/(sici)1522-2675(19990804)82:8%3c1211::aidhlca1211%3e3.0.co;2-k	https://doi.org/10.1002/(sici)1522-2675(19990804)82:8%3c1211::aidhlca1211%3e3.0.co;2-k	NOUN
admet-2859	363	1	[	[	X
admet-2859	363	2	43	43	NUM
admet-2859	363	3	]	]	X
admet-2859	363	4	a.	a.	NOUN
admet-2859	363	5	singh	singh	PROPN
admet-2859	363	6	,	,	PUNCT
admet-2859	363	7	m.	m.	NOUN
admet-2859	363	8	pallastrelli	pallastrelli	PROPN
admet-2859	363	9	,	,	PUNCT
admet-2859	363	10	m.	m.	PROPN
admet-2859	363	11	santoro	santoro	PROPN
admet-2859	363	12	.	.	PUNCT
admet-2859	364	1	direct	direct	ADJ
admet-2859	364	2	chiral	chiral	ADJ
admet-2859	364	3	separations	separation	NOUN
admet-2859	364	4	of	of	ADP
admet-2859	364	5	third	third	ADJ
admet-2859	364	6	generation	generation	NOUN
admet-2859	364	7	b	b	NOUN
admet-2859	364	8	-	-	PUNCT
admet-2859	364	9	blockers	blocker	NOUN
admet-2859	364	10	through	through	ADP
admet-2859	364	11	high	high	ADJ
admet-2859	364	12	performance	performance	NOUN
admet-2859	364	13	liquid	liquid	NOUN
admet-2859	364	14	chromatography	chromatography	NOUN
admet-2859	364	15	.	.	PUNCT
admet-2859	365	1	scientia	scientia	PROPN
admet-2859	365	2	chromatographica	chromatographica	PROPN
admet-2859	365	3	7	7	NUM
admet-2859	365	4	(	(	PUNCT
admet-2859	365	5	2015	2015	NUM
admet-2859	365	6	)	)	PUNCT
admet-2859	365	7	65	65	NUM
admet-2859	365	8	-	-	SYM
admet-2859	365	9	84	84	NUM
admet-2859	365	10	.	.	PUNCT
admet-2859	366	1	https://doi.org/10.4322/sc.2015.017	https://doi.org/10.4322/sc.2015.017	PUNCT
admet-2859	367	1	[	[	X
admet-2859	367	2	44	44	NUM
admet-2859	367	3	]	]	X
admet-2859	367	4	n.a	n.a	PROPN
admet-2859	367	5	.	.	PROPN
admet-2859	367	6	al	al	PROPN
admet-2859	367	7	-	-	PUNCT
admet-2859	367	8	rawashdeh	rawashdeh	PROPN
admet-2859	367	9	,	,	PUNCT
admet-2859	367	10	k.s	k.s	PROPN
admet-2859	367	11	.	.	PUNCT
admet-2859	367	12	al	al	PROPN
admet-2859	367	13	-	-	PUNCT
admet-2859	367	14	sadeh	sadeh	PROPN
admet-2859	367	15	,	,	PUNCT
admet-2859	367	16	m.b	m.b	PROPN
admet-2859	367	17	.	.	PROPN
admet-2859	367	18	al	al	PROPN
admet-2859	367	19	-	-	PUNCT
admet-2859	367	20	bitar	bitar	PROPN
admet-2859	367	21	.	.	PUNCT
admet-2859	368	1	physicochemical	physicochemical	ADJ
admet-2859	368	2	study	study	NOUN
admet-2859	368	3	on	on	ADP
admet-2859	368	4	microencapsulation	microencapsulation	NOUN
admet-2859	368	5	of	of	ADP
admet-2859	368	6	hydroxypropyl	hydroxypropyl	NOUN
admet-2859	368	7	-	-	PUNCT
admet-2859	368	8	beta	beta	NOUN
admet-2859	368	9	-	-	PUNCT
admet-2859	368	10	cyclodextrin	cyclodextrin	NOUN
admet-2859	368	11	in	in	ADP
admet-2859	368	12	dermal	dermal	ADJ
admet-2859	368	13	preparations	preparation	NOUN
admet-2859	368	14	.	.	PUNCT
admet-2859	369	1	drug	drug	PROPN
admet-2859	369	2	dev	dev	PROPN
admet-2859	369	3	ind	ind	PROPN
admet-2859	369	4	pharm	pharm	PROPN
admet-2859	369	5	36	36	NUM
admet-2859	369	6	(	(	PUNCT
admet-2859	369	7	2010	2010	NUM
admet-2859	369	8	)	)	PUNCT
admet-2859	369	9	688	688	NUM
admet-2859	369	10	-	-	SYM
admet-2859	369	11	697	697	NUM
admet-2859	369	12	.	.	PUNCT
admet-2859	369	13	https://doi.org/10.3109/03639040903449738	https://doi.org/10.3109/03639040903449738	NOUN
admet-2859	370	1	[	[	X
admet-2859	370	2	45	45	NUM
admet-2859	370	3	]	]	PUNCT
admet-2859	370	4	patient	patient	ADJ
admet-2859	370	5	information	information	NOUN
admet-2859	370	6	of	of	ADP
admet-2859	370	7	sporanox	sporanox	NOUN
admet-2859	370	8	(	(	PUNCT
admet-2859	370	9	itraconazole	itraconazole	NOUN
admet-2859	370	10	)	)	PUNCT
admet-2859	370	11	capsules	capsule	NOUN
admet-2859	370	12	.	.	PUNCT
admet-2859	371	1	https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020083s062lbl.pdf	https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020083s062lbl.pdf	PUNCT
admet-2859	371	2	(	(	PUNCT
admet-2859	371	3	accessed	access	VERB
admet-2859	371	4	24	24	NUM
admet-2859	371	5	june	june	PROPN
admet-2859	371	6	2025	2025	NUM
admet-2859	371	7	)	)	PUNCT
admet-2859	372	1	[	[	X
admet-2859	372	2	46	46	NUM
admet-2859	372	3	]	]	PUNCT
admet-2859	372	4	a.	a.	PROPN
admet-2859	372	5	dahan	dahan	PROPN
admet-2859	372	6	,	,	PUNCT
admet-2859	372	7	j.m	j.m	PROPN
admet-2859	372	8	.	.	PROPN
admet-2859	372	9	miller	miller	PROPN
admet-2859	372	10	,	,	PUNCT
admet-2859	372	11	a.	a.	NOUN
admet-2859	372	12	hoffman	hoffman	PROPN
admet-2859	372	13	,	,	PUNCT
admet-2859	372	14	g.e	g.e	PROPN
admet-2859	372	15	.	.	PROPN
admet-2859	372	16	amidon	amidon	PROPN
admet-2859	372	17	,	,	PUNCT
admet-2859	372	18	g.l	g.l	PROPN
admet-2859	372	19	.	.	PROPN
admet-2859	372	20	amidon	amidon	PROPN
admet-2859	372	21	.	.	PUNCT
admet-2859	373	1	the	the	DET
admet-2859	373	2	solubility	solubility	NOUN
admet-2859	373	3	-	-	PUNCT
admet-2859	373	4	permeability	permeability	NOUN
admet-2859	373	5	interplay	interplay	NOUN
admet-2859	373	6	in	in	ADP
admet-2859	373	7	using	use	VERB
admet-2859	373	8	cyclodextrins	cyclodextrin	NOUN
admet-2859	373	9	as	as	ADP
admet-2859	373	10	pharmaceutical	pharmaceutical	ADJ
admet-2859	373	11	solubilizers	solubilizer	NOUN
admet-2859	373	12	:	:	PUNCT
admet-2859	373	13	mechanistic	mechanistic	ADJ
admet-2859	373	14	modeling	modeling	NOUN
admet-2859	373	15	and	and	CCONJ
admet-2859	373	16	application	application	NOUN
admet-2859	373	17	to	to	ADP
admet-2859	373	18	progesterone	progesterone	NOUN
admet-2859	373	19	.	.	PUNCT
admet-2859	374	1	journal	journal	PROPN
admet-2859	374	2	of	of	ADP
admet-2859	374	3	pharmaceutical	pharmaceutical	PROPN
admet-2859	374	4	sciences	science	NOUN
admet-2859	374	5	99	99	NUM
admet-2859	374	6	(	(	PUNCT
admet-2859	374	7	2010	2010	NUM
admet-2859	374	8	)	)	PUNCT
admet-2859	374	9	2739	2739	NUM
admet-2859	374	10	-	-	SYM
admet-2859	374	11	2749	2749	NUM
admet-2859	374	12	https://doi.org/10.1002/jps.22033	https://doi.org/10.1002/jps.22033	VERB
admet-2859	374	13	©	©	PROPN
admet-2859	374	14	2025	2025	NUM
admet-2859	374	15	by	by	ADP
admet-2859	374	16	the	the	DET
admet-2859	374	17	authors	author	NOUN
admet-2859	374	18	;	;	PUNCT
admet-2859	374	19	licensee	licensee	PROPN
admet-2859	374	20	iapc	iapc	PROPN
admet-2859	374	21	,	,	PUNCT
admet-2859	374	22	zagreb	zagreb	PROPN
admet-2859	374	23	,	,	PUNCT
admet-2859	374	24	croatia	croatia	PROPN
admet-2859	374	25	.	.	PUNCT
admet-2859	375	1	this	this	DET
admet-2859	375	2	article	article	NOUN
admet-2859	375	3	is	be	AUX
admet-2859	375	4	an	an	DET
admet-2859	375	5	open	open	ADJ
admet-2859	375	6	-	-	PUNCT
admet-2859	375	7	access	access	NOUN
admet-2859	375	8	article	article	NOUN
admet-2859	375	9	distributed	distribute	VERB
admet-2859	375	10	under	under	ADP
admet-2859	375	11	the	the	DET
admet-2859	375	12	terms	term	NOUN
admet-2859	375	13	and	and	CCONJ
admet-2859	375	14	conditions	condition	NOUN
admet-2859	375	15	of	of	ADP
admet-2859	375	16	the	the	DET
admet-2859	375	17	creative	creative	ADJ
admet-2859	375	18	commons	common	NOUN
admet-2859	375	19	attribution	attribution	NOUN
admet-2859	375	20	license	license	NOUN
admet-2859	375	21	(	(	PUNCT
admet-2859	375	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-2859	375	23	)	)	PUNCT
admet-2859	375	24	https://doi.org/10.1002/(sici)1522-2675(19990804)82:8%3c1211::aid-hlca1211%3e3.0.co;2-k	https://doi.org/10.1002/(sici)1522-2675(19990804)82:8%3c1211::aid-hlca1211%3e3.0.co;2-k	PROPN
admet-2859	375	25	https://doi.org/10.1002/(sici)1522-2675(19990804)82:8%3c1211::aid-hlca1211%3e3.0.co;2-k	https://doi.org/10.1002/(sici)1522-2675(19990804)82:8%3c1211::aid-hlca1211%3e3.0.co;2-k	PROPN
admet-2859	375	26	https://doi.org/10.4322/sc.2015.017	https://doi.org/10.4322/sc.2015.017	ADJ
admet-2859	375	27	https://doi.org/10.3109/03639040903449738	https://doi.org/10.3109/03639040903449738	NOUN
admet-2859	375	28	https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020083s062lbl.pdf	https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020083s062lbl.pdf	PROPN
admet-2859	375	29	https://doi.org/10.1002/jps.22033	https://doi.org/10.1002/jps.22033	PROPN
admet-2859	375	30	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN