id	sid	tid	token	lemma	pos
admet-3065	1	1	liposome	liposome	NOUN
admet-3065	1	2	-	-	PUNCT
admet-3065	1	3	mediated	mediate	VERB
admet-3065	1	4	gene	gene	NOUN
admet-3065	1	5	delivery	delivery	NOUN
admet-3065	1	6	:	:	PUNCT
admet-3065	1	7	a	a	DET
admet-3065	1	8	comprehensive	comprehensive	ADJ
admet-3065	1	9	review	review	NOUN
admet-3065	1	10	of	of	ADP
admet-3065	1	11	biophysical	biophysical	ADJ
admet-3065	1	12	parameters	parameter	NOUN
admet-3065	1	13	,	,	PUNCT
admet-3065	1	14	lipid	lipid	NOUN
admet-3065	1	15	composition	composition	NOUN
admet-3065	1	16	and	and	CCONJ
admet-3065	1	17	targeting	target	VERB
admet-3065	1	18	strategies	strategy	NOUN
admet-3065	1	19	doi	doi	NOUN
admet-3065	1	20	:	:	PUNCT
admet-3065	1	21	http://doi.org/10.5599/admet.3065	http://doi.org/10.5599/admet.3065	PROPN
admet-3065	1	22	1	1	NUM
admet-3065	1	23	admet	admet	X
admet-3065	1	24	&	&	CCONJ
admet-3065	1	25	dmpk	dmpk	PROPN
admet-3065	1	26	00(0	00(0	PROPN
admet-3065	1	27	)	)	PUNCT
admet-3065	1	28	(	(	PUNCT
admet-3065	1	29	2025	2025	NUM
admet-3065	1	30	)	)	PUNCT
admet-3065	1	31	3065	3065	NUM
admet-3065	1	32	;	;	PUNCT
admet-3065	1	33	doi	doi	NOUN
admet-3065	1	34	:	:	PUNCT
admet-3065	1	35	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PRON
admet-3065	1	36	open	open	VERB
admet-3065	1	37	access	access	NOUN
admet-3065	1	38	:	:	PUNCT
admet-3065	1	39	issn	issn	PROPN
admet-3065	1	40	:	:	PUNCT
admet-3065	1	41	1848	1848	NUM
admet-3065	1	42	-	-	SYM
admet-3065	1	43	7718	7718	NUM
admet-3065	1	44	https://pub.iapchem.org/ojs/index.php/admet	https://pub.iapchem.org/ojs/index.php/admet	NOUN
admet-3065	1	45	review	review	VERB
admet-3065	1	46	paper	paper	NOUN
admet-3065	1	47	liposome	liposome	NOUN
admet-3065	1	48	-	-	PUNCT
admet-3065	1	49	mediated	mediate	VERB
admet-3065	1	50	gene	gene	NOUN
admet-3065	1	51	delivery	delivery	NOUN
admet-3065	1	52	:	:	PUNCT
admet-3065	1	53	a	a	DET
admet-3065	1	54	comprehensive	comprehensive	ADJ
admet-3065	1	55	review	review	NOUN
admet-3065	1	56	of	of	ADP
admet-3065	1	57	biophysical	biophysical	ADJ
admet-3065	1	58	parameters	parameter	NOUN
admet-3065	1	59	,	,	PUNCT
admet-3065	1	60	lipid	lipid	NOUN
admet-3065	1	61	composition	composition	NOUN
admet-3065	1	62	and	and	CCONJ
admet-3065	1	63	targeting	targeting	NOUN
admet-3065	1	64	strategies	strategy	NOUN
admet-3065	1	65	erfan	erfan	NOUN
admet-3065	2	1	jafari	jafari	ADJ
admet-3065	2	2	saleh1	saleh1	PROPN
admet-3065	2	3	,	,	PUNCT
admet-3065	2	4	mohammad	mohammad	PROPN
admet-3065	2	5	satari1,2	satari1,2	PROPN
admet-3065	2	6	,	,	PUNCT
admet-3065	2	7	*	*	PUNCT
admet-3065	2	8	and	and	CCONJ
admet-3065	2	9	behnam	behnam	VERB
admet-3065	2	10	hajipour	hajipour	PROPN
admet-3065	2	11	-	-	PUNCT
admet-3065	2	12	verdom3,4	verdom3,4	PROPN
admet-3065	2	13	1department	1department	NUM
admet-3065	2	14	of	of	ADP
admet-3065	2	15	biology	biology	NOUN
admet-3065	2	16	,	,	PUNCT
admet-3065	2	17	faculty	faculty	NOUN
admet-3065	2	18	of	of	ADP
admet-3065	2	19	sciences	science	NOUN
admet-3065	2	20	,	,	PUNCT
admet-3065	2	21	university	university	NOUN
admet-3065	2	22	of	of	ADP
admet-3065	2	23	malayer	malayer	NOUN
admet-3065	2	24	,	,	PUNCT
admet-3065	2	25	malayer	malayer	PROPN
admet-3065	2	26	,	,	PUNCT
admet-3065	2	27	iran	iran	PROPN
admet-3065	2	28	2department	2department	NUM
admet-3065	2	29	of	of	ADP
admet-3065	2	30	biotechnology	biotechnology	NOUN
admet-3065	2	31	,	,	PUNCT
admet-3065	2	32	faculty	faculty	NOUN
admet-3065	2	33	of	of	ADP
admet-3065	2	34	interdisciplinary	interdisciplinary	ADJ
admet-3065	2	35	science	science	NOUN
admet-3065	2	36	and	and	CCONJ
admet-3065	2	37	technology	technology	NOUN
admet-3065	2	38	,	,	PUNCT
admet-3065	2	39	malayer	malayer	PROPN
admet-3065	2	40	university	university	PROPN
admet-3065	2	41	,	,	PUNCT
admet-3065	2	42	malayer	malayer	PROPN
admet-3065	2	43	,	,	PUNCT
admet-3065	2	44	iran	iran	PROPN
admet-3065	2	45	3integrative	3integrative	NUM
admet-3065	2	46	oncology	oncology	NOUN
admet-3065	2	47	department	department	NOUN
admet-3065	2	48	,	,	PUNCT
admet-3065	2	49	breast	breast	NOUN
admet-3065	2	50	cancer	cancer	NOUN
admet-3065	2	51	research	research	NOUN
admet-3065	2	52	center	center	NOUN
admet-3065	2	53	,	,	PUNCT
admet-3065	2	54	motamed	motamed	PROPN
admet-3065	2	55	cancer	cancer	PROPN
admet-3065	2	56	institute	institute	PROPN
admet-3065	2	57	,	,	PUNCT
admet-3065	2	58	academic	academic	ADJ
admet-3065	2	59	center	center	NOUN
admet-3065	2	60	for	for	ADP
admet-3065	2	61	education	education	NOUN
admet-3065	2	62	,	,	PUNCT
admet-3065	2	63	culture	culture	NOUN
admet-3065	2	64	and	and	CCONJ
admet-3065	2	65	research	research	NOUN
admet-3065	2	66	(	(	PUNCT
admet-3065	2	67	acecr	acecr	NOUN
admet-3065	2	68	)	)	PUNCT
admet-3065	2	69	,	,	PUNCT
admet-3065	2	70	tehran	tehran	NOUN
admet-3065	2	71	,	,	PUNCT
admet-3065	2	72	1517964311	1517964311	NUM
admet-3065	2	73	,	,	PUNCT
admet-3065	2	74	iran	iran	PROPN
admet-3065	2	75	4department	4department	NUM
admet-3065	2	76	of	of	ADP
admet-3065	2	77	biophysics	biophysic	NOUN
admet-3065	2	78	,	,	PUNCT
admet-3065	2	79	faculty	faculty	NOUN
admet-3065	2	80	of	of	ADP
admet-3065	2	81	biological	biological	ADJ
admet-3065	2	82	sciences	science	NOUN
admet-3065	2	83	,	,	PUNCT
admet-3065	2	84	tarbiat	tarbiat	PROPN
admet-3065	2	85	modares	modares	PROPN
admet-3065	2	86	university	university	PROPN
admet-3065	2	87	,	,	PUNCT
admet-3065	2	88	tehran	tehran	PROPN
admet-3065	2	89	,	,	PUNCT
admet-3065	2	90	14115	14115	NUM
admet-3065	2	91	-	-	SYM
admet-3065	2	92	154	154	NUM
admet-3065	2	93	,	,	PUNCT
admet-3065	2	94	iran	iran	PROPN
admet-3065	2	95	*	*	PUNCT
admet-3065	2	96	corresponding	correspond	VERB
admet-3065	2	97	author	author	NOUN
admet-3065	2	98	:	:	PUNCT
admet-3065	2	99	e	e	NOUN
admet-3065	2	100	-	-	NOUN
admet-3065	2	101	mail	mail	NOUN
admet-3065	2	102	:	:	PUNCT
admet-3065	2	103	m.satari@malayeru.ac.ir	m.satari@malayeru.ac.ir	NOUN
admet-3065	2	104	;	;	PUNCT
admet-3065	2	105	tel	tel	PROPN
admet-3065	2	106	.	.	PUNCT
admet-3065	2	107	:	:	PUNCT
admet-3065	2	108	+98	+98	NUM
admet-3065	2	109	-	-	PUNCT
admet-3065	2	110	81	81	NUM
admet-3065	2	111	-	-	PUNCT
admet-3065	2	112	3245	3245	NUM
admet-3065	2	113	-	-	SYM
admet-3065	2	114	7427	7427	NUM
admet-3065	2	115	;	;	PUNCT
admet-3065	2	116	fax	fax	NOUN
admet-3065	2	117	:	:	PUNCT
admet-3065	2	118	+98	+98	ADJ
admet-3065	2	119	-	-	PUNCT
admet-3065	2	120	81	81	NUM
admet-3065	2	121	-	-	PUNCT
admet-3065	2	122	3245	3245	NUM
admet-3065	2	123	-	-	PUNCT
admet-3065	2	124	7333	7333	NUM
admet-3065	2	125	received	receive	VERB
admet-3065	2	126	:	:	PUNCT
admet-3065	2	127	september	september	PROPN
admet-3065	2	128	22	22	NUM
admet-3065	2	129	,	,	PUNCT
admet-3065	2	130	2025	2025	NUM
admet-3065	2	131	;	;	PUNCT
admet-3065	2	132	revised	revise	VERB
admet-3065	2	133	:	:	PUNCT
admet-3065	2	134	november	november	PROPN
admet-3065	2	135	19	19	NUM
admet-3065	2	136	,	,	PUNCT
admet-3065	2	137	2025	2025	NUM
admet-3065	2	138	;	;	PUNCT
admet-3065	2	139	published	publish	VERB
admet-3065	2	140	:	:	PUNCT
admet-3065	2	141	december	december	PROPN
admet-3065	2	142	02	02	NUM
admet-3065	2	143	,	,	PUNCT
admet-3065	2	144	2025	2025	NUM
admet-3065	2	145	abstract	abstract	ADJ
admet-3065	2	146	background	background	NOUN
admet-3065	2	147	and	and	CCONJ
admet-3065	2	148	purpose	purpose	NOUN
admet-3065	2	149	:	:	PUNCT
admet-3065	2	150	gene	gene	NOUN
admet-3065	2	151	therapy	therapy	NOUN
admet-3065	2	152	has	have	AUX
admet-3065	2	153	emerged	emerge	VERB
admet-3065	2	154	as	as	ADP
admet-3065	2	155	a	a	DET
admet-3065	2	156	transformative	transformative	ADJ
admet-3065	2	157	strategy	strategy	NOUN
admet-3065	2	158	for	for	ADP
admet-3065	2	159	treating	treat	VERB
admet-3065	2	160	genetic	genetic	ADJ
admet-3065	2	161	and	and	CCONJ
admet-3065	2	162	acquired	acquire	VERB
admet-3065	2	163	disorders	disorder	NOUN
admet-3065	2	164	,	,	PUNCT
admet-3065	2	165	but	but	CCONJ
admet-3065	2	166	its	its	PRON
admet-3065	2	167	clinical	clinical	ADJ
admet-3065	2	168	success	success	NOUN
admet-3065	2	169	relies	rely	VERB
admet-3065	2	170	heavily	heavily	ADV
admet-3065	2	171	on	on	ADP
admet-3065	2	172	the	the	DET
admet-3065	2	173	development	development	NOUN
admet-3065	2	174	of	of	ADP
admet-3065	2	175	safe	safe	ADJ
admet-3065	2	176	,	,	PUNCT
admet-3065	2	177	efficient	efficient	ADJ
admet-3065	2	178	,	,	PUNCT
admet-3065	2	179	and	and	CCONJ
admet-3065	2	180	targetspecific	targetspecific	ADJ
admet-3065	2	181	delivery	delivery	NOUN
admet-3065	2	182	vectors	vector	NOUN
admet-3065	2	183	.	.	PUNCT
admet-3065	3	1	experimental	experimental	ADJ
admet-3065	3	2	approach	approach	NOUN
admet-3065	3	3	:	:	PUNCT
admet-3065	3	4	the	the	DET
admet-3065	3	5	paper	paper	NOUN
admet-3065	3	6	systematically	systematically	ADV
admet-3065	3	7	analysed	analyse	VERB
admet-3065	3	8	published	publish	VERB
admet-3065	3	9	evidence	evidence	NOUN
admet-3065	3	10	on	on	ADP
admet-3065	3	11	liposome	liposome	NOUN
admet-3065	3	12	composition	composition	NOUN
admet-3065	3	13	,	,	PUNCT
admet-3065	3	14	physicochemical	physicochemical	ADJ
admet-3065	3	15	behaviour	behaviour	NOUN
admet-3065	3	16	,	,	PUNCT
admet-3065	3	17	targeting	target	VERB
admet-3065	3	18	strategies	strategy	NOUN
admet-3065	3	19	,	,	PUNCT
admet-3065	3	20	and	and	CCONJ
admet-3065	3	21	their	their	PRON
admet-3065	3	22	applications	application	NOUN
admet-3065	3	23	in	in	ADP
admet-3065	3	24	delivering	deliver	VERB
admet-3065	3	25	diverse	diverse	ADJ
admet-3065	3	26	nucleic	nucleic	ADJ
admet-3065	3	27	acids	acid	NOUN
admet-3065	3	28	,	,	PUNCT
admet-3065	3	29	with	with	ADP
admet-3065	3	30	emphasis	emphasis	NOUN
admet-3065	3	31	on	on	ADP
admet-3065	3	32	the	the	DET
admet-3065	3	33	structure	structure	NOUN
admet-3065	3	34	-	-	PUNCT
admet-3065	3	35	function	function	NOUN
admet-3065	3	36	relationships	relationship	NOUN
admet-3065	3	37	of	of	ADP
admet-3065	3	38	lipid	lipid	ADJ
admet-3065	3	39	components	component	NOUN
admet-3065	3	40	and	and	CCONJ
admet-3065	3	41	the	the	DET
admet-3065	3	42	impact	impact	NOUN
admet-3065	3	43	of	of	ADP
admet-3065	3	44	biophysical	biophysical	ADJ
admet-3065	3	45	parameters	parameter	NOUN
admet-3065	3	46	on	on	ADP
admet-3065	3	47	transfection	transfection	NOUN
admet-3065	3	48	efficiency	efficiency	NOUN
admet-3065	3	49	.	.	PUNCT
admet-3065	4	1	key	key	ADJ
admet-3065	4	2	results	result	NOUN
admet-3065	4	3	:	:	PUNCT
admet-3065	4	4	current	current	ADJ
admet-3065	4	5	findings	finding	NOUN
admet-3065	4	6	demonstrate	demonstrate	VERB
admet-3065	4	7	that	that	SCONJ
admet-3065	4	8	the	the	DET
admet-3065	4	9	molecular	molecular	ADJ
admet-3065	4	10	architecture	architecture	NOUN
admet-3065	4	11	of	of	ADP
admet-3065	4	12	cationic	cationic	ADJ
admet-3065	4	13	,	,	PUNCT
admet-3065	4	14	neutral	neutral	ADJ
admet-3065	4	15	,	,	PUNCT
admet-3065	4	16	and	and	CCONJ
admet-3065	4	17	anionic	anionic	ADJ
admet-3065	4	18	lipids	lipid	NOUN
admet-3065	4	19	,	,	PUNCT
admet-3065	4	20	particularly	particularly	ADV
admet-3065	4	21	variations	variation	NOUN
admet-3065	4	22	in	in	ADP
admet-3065	4	23	head	head	NOUN
admet-3065	4	24	groups	group	NOUN
admet-3065	4	25	,	,	PUNCT
admet-3065	4	26	linkers	linker	NOUN
admet-3065	4	27	,	,	PUNCT
admet-3065	4	28	and	and	CCONJ
admet-3065	4	29	hydrophobic	hydrophobic	NOUN
admet-3065	4	30	tails	tail	NOUN
admet-3065	4	31	,	,	PUNCT
admet-3065	4	32	strongly	strongly	ADV
admet-3065	4	33	dictates	dictate	VERB
admet-3065	4	34	liposome	liposome	VERB
admet-3065	4	35	stability	stability	NOUN
admet-3065	4	36	,	,	PUNCT
admet-3065	4	37	cellular	cellular	ADJ
admet-3065	4	38	uptake	uptake	NOUN
admet-3065	4	39	,	,	PUNCT
admet-3065	4	40	and	and	CCONJ
admet-3065	4	41	cargo	cargo	NOUN
admet-3065	4	42	release	release	NOUN
admet-3065	4	43	.	.	PUNCT
admet-3065	5	1	biophysical	biophysical	ADJ
admet-3065	5	2	attributes	attribute	NOUN
admet-3065	5	3	such	such	ADJ
admet-3065	5	4	as	as	ADP
admet-3065	5	5	vesicle	vesicle	NOUN
admet-3065	5	6	size	size	NOUN
admet-3065	5	7	,	,	PUNCT
admet-3065	5	8	zeta	zeta	NOUN
admet-3065	5	9	potential	potential	NOUN
admet-3065	5	10	,	,	PUNCT
admet-3065	5	11	membrane	membrane	ADJ
admet-3065	5	12	fluidity	fluidity	NOUN
admet-3065	5	13	,	,	PUNCT
admet-3065	5	14	fusion	fusion	NOUN
admet-3065	5	15	capacity	capacity	NOUN
admet-3065	5	16	,	,	PUNCT
admet-3065	5	17	and	and	CCONJ
admet-3065	5	18	pegylation	pegylation	NOUN
admet-3065	5	19	were	be	AUX
admet-3065	5	20	identified	identify	VERB
admet-3065	5	21	as	as	ADP
admet-3065	5	22	major	major	ADJ
admet-3065	5	23	determinants	determinant	NOUN
admet-3065	5	24	of	of	ADP
admet-3065	5	25	in	in	ADP
admet-3065	5	26	vivo	vivo	NOUN
admet-3065	5	27	fate	fate	NOUN
admet-3065	5	28	.	.	PUNCT
admet-3065	6	1	active	active	ADJ
admet-3065	6	2	targeting	target	VERB
admet-3065	6	3	through	through	ADP
admet-3065	6	4	ligands	ligand	NOUN
admet-3065	6	5	,	,	PUNCT
admet-3065	6	6	including	include	VERB
admet-3065	6	7	antibodies	antibody	NOUN
admet-3065	6	8	,	,	PUNCT
admet-3065	6	9	peptides	peptide	NOUN
admet-3065	6	10	,	,	PUNCT
admet-3065	6	11	folate	folate	NOUN
admet-3065	6	12	,	,	PUNCT
admet-3065	6	13	and	and	CCONJ
admet-3065	6	14	aptamers	aptamer	NOUN
admet-3065	6	15	,	,	PUNCT
admet-3065	6	16	enhances	enhance	VERB
admet-3065	6	17	cell	cell	NOUN
admet-3065	6	18	-	-	PUNCT
admet-3065	6	19	specific	specific	ADJ
admet-3065	6	20	delivery	delivery	NOUN
admet-3065	6	21	,	,	PUNCT
admet-3065	6	22	while	while	SCONJ
admet-3065	6	23	combinatorial	combinatorial	ADJ
admet-3065	6	24	approaches	approach	NOUN
admet-3065	6	25	with	with	ADP
admet-3065	6	26	physical	physical	ADJ
admet-3065	6	27	enhancement	enhancement	NOUN
admet-3065	6	28	techniques	technique	NOUN
admet-3065	6	29	such	such	ADJ
admet-3065	6	30	as	as	ADP
admet-3065	6	31	sonoporation	sonoporation	NOUN
admet-3065	6	32	and	and	CCONJ
admet-3065	6	33	electroporation	electroporation	NOUN
admet-3065	6	34	further	far	ADV
admet-3065	6	35	improve	improve	VERB
admet-3065	6	36	nucleic	nucleic	ADJ
admet-3065	6	37	acid	acid	NOUN
admet-3065	6	38	transport	transport	NOUN
admet-3065	6	39	.	.	PUNCT
admet-3065	7	1	conclusion	conclusion	NOUN
admet-3065	7	2	:	:	PUNCT
admet-3065	7	3	by	by	ADP
admet-3065	7	4	integrating	integrate	VERB
admet-3065	7	5	structural	structural	ADJ
admet-3065	7	6	,	,	PUNCT
admet-3065	7	7	functional	functional	ADJ
admet-3065	7	8	,	,	PUNCT
admet-3065	7	9	and	and	CCONJ
admet-3065	7	10	application	application	NOUN
admet-3065	7	11	-	-	PUNCT
admet-3065	7	12	based	base	VERB
admet-3065	7	13	insights	insight	NOUN
admet-3065	7	14	,	,	PUNCT
admet-3065	7	15	this	this	DET
admet-3065	7	16	review	review	NOUN
admet-3065	7	17	highlights	highlight	VERB
admet-3065	7	18	key	key	ADJ
admet-3065	7	19	design	design	NOUN
admet-3065	7	20	principles	principle	NOUN
admet-3065	7	21	for	for	ADP
admet-3065	7	22	optimizing	optimize	VERB
admet-3065	7	23	next	next	ADJ
admet-3065	7	24	-	-	PUNCT
admet-3065	7	25	generation	generation	NOUN
admet-3065	7	26	liposomal	liposomal	ADJ
admet-3065	7	27	vectors	vector	NOUN
admet-3065	7	28	,	,	PUNCT
admet-3065	7	29	although	although	SCONJ
admet-3065	7	30	challenges	challenge	NOUN
admet-3065	7	31	remain	remain	VERB
admet-3065	7	32	in	in	ADP
admet-3065	7	33	achieving	achieve	VERB
admet-3065	7	34	consistent	consistent	ADJ
admet-3065	7	35	in	in	ADP
admet-3065	7	36	vivo	vivo	ADJ
admet-3065	7	37	performance	performance	NOUN
admet-3065	7	38	and	and	CCONJ
admet-3065	7	39	clinical	clinical	ADJ
admet-3065	7	40	translation	translation	NOUN
admet-3065	7	41	.	.	PUNCT
admet-3065	8	1	the	the	DET
admet-3065	8	2	work	work	NOUN
admet-3065	8	3	advances	advance	VERB
admet-3065	8	4	the	the	DET
admet-3065	8	5	field	field	NOUN
admet-3065	8	6	by	by	ADP
admet-3065	8	7	offering	offer	VERB
admet-3065	8	8	a	a	DET
admet-3065	8	9	unified	unified	ADJ
admet-3065	8	10	framework	framework	NOUN
admet-3065	8	11	to	to	PART
admet-3065	8	12	guide	guide	VERB
admet-3065	8	13	rational	rational	ADJ
admet-3065	8	14	engineering	engineering	NOUN
admet-3065	8	15	of	of	ADP
admet-3065	8	16	liposomal	liposomal	ADJ
admet-3065	8	17	platforms	platform	NOUN
admet-3065	8	18	for	for	ADP
admet-3065	8	19	gene	gene	NOUN
admet-3065	8	20	therapy	therapy	NOUN
admet-3065	8	21	.	.	PUNCT
admet-3065	9	1	©	©	PROPN
admet-3065	9	2	2025	2025	NUM
admet-3065	9	3	by	by	ADP
admet-3065	9	4	the	the	DET
admet-3065	9	5	authors	author	NOUN
admet-3065	9	6	.	.	PUNCT
admet-3065	10	1	this	this	DET
admet-3065	10	2	article	article	NOUN
admet-3065	10	3	is	be	AUX
admet-3065	10	4	an	an	DET
admet-3065	10	5	open	open	ADJ
admet-3065	10	6	-	-	PUNCT
admet-3065	10	7	access	access	NOUN
admet-3065	10	8	article	article	NOUN
admet-3065	10	9	distributed	distribute	VERB
admet-3065	10	10	under	under	ADP
admet-3065	10	11	the	the	DET
admet-3065	10	12	terms	term	NOUN
admet-3065	10	13	and	and	CCONJ
admet-3065	10	14	conditions	condition	NOUN
admet-3065	10	15	of	of	ADP
admet-3065	10	16	the	the	DET
admet-3065	10	17	creative	creative	ADJ
admet-3065	10	18	commons	common	NOUN
admet-3065	10	19	attribution	attribution	NOUN
admet-3065	10	20	license	license	NOUN
admet-3065	10	21	(	(	PUNCT
admet-3065	10	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-3065	10	23	)	)	PUNCT
admet-3065	10	24	.	.	PUNCT
admet-3065	11	1	keywords	keyword	VERB
admet-3065	11	2	cationic	cationic	ADJ
admet-3065	11	3	lipids	lipid	NOUN
admet-3065	11	4	;	;	PUNCT
admet-3065	11	5	non	non	ADJ
admet-3065	11	6	-	-	ADJ
admet-3065	11	7	viral	viral	ADJ
admet-3065	11	8	vector	vector	NOUN
admet-3065	11	9	;	;	PUNCT
admet-3065	11	10	gene	gene	NOUN
admet-3065	11	11	therapy	therapy	NOUN
admet-3065	11	12	;	;	PUNCT
admet-3065	11	13	active	active	ADJ
admet-3065	11	14	targeting	targeting	NOUN
admet-3065	11	15	;	;	PUNCT
admet-3065	11	16	transfection	transfection	NOUN
admet-3065	11	17	introduction	introduction	NOUN
admet-3065	11	18	the	the	DET
admet-3065	11	19	rising	rise	VERB
admet-3065	11	20	prevalence	prevalence	NOUN
admet-3065	11	21	of	of	ADP
admet-3065	11	22	genetic	genetic	ADJ
admet-3065	11	23	disorders	disorder	NOUN
admet-3065	11	24	and	and	CCONJ
admet-3065	11	25	cancers	cancer	NOUN
admet-3065	11	26	globally	globally	ADV
admet-3065	11	27	has	have	AUX
admet-3065	11	28	underscored	underscore	VERB
admet-3065	11	29	the	the	DET
admet-3065	11	30	need	need	NOUN
admet-3065	11	31	for	for	ADP
admet-3065	11	32	newer	new	ADJ
admet-3065	11	33	therapeutic	therapeutic	ADJ
admet-3065	11	34	approaches	approach	NOUN
admet-3065	11	35	7	7	NUM
admet-3065	11	36	.	.	PUNCT
admet-3065	12	1	gene	gene	NOUN
admet-3065	12	2	therapy	therapy	NOUN
admet-3065	12	3	holds	hold	VERB
admet-3065	12	4	great	great	ADJ
admet-3065	12	5	promise	promise	NOUN
admet-3065	12	6	due	due	ADP
admet-3065	12	7	to	to	ADP
admet-3065	12	8	its	its	PRON
admet-3065	12	9	ability	ability	NOUN
admet-3065	12	10	to	to	PART
admet-3065	12	11	target	target	VERB
admet-3065	12	12	and	and	CCONJ
admet-3065	12	13	modify	modify	VERB
admet-3065	12	14	genetic	genetic	ADJ
admet-3065	12	15	material	material	NOUN
admet-3065	12	16	at	at	ADP
admet-3065	12	17	the	the	DET
admet-3065	12	18	cellular	cellular	ADJ
admet-3065	12	19	level	level	NOUN
admet-3065	12	20	,	,	PUNCT
admet-3065	12	21	offering	offer	VERB
admet-3065	12	22	the	the	DET
admet-3065	12	23	prospect	prospect	NOUN
admet-3065	12	24	of	of	ADP
admet-3065	12	25	a	a	DET
admet-3065	12	26	cure	cure	NOUN
admet-3065	12	27	for	for	ADP
admet-3065	12	28	diseases	disease	NOUN
admet-3065	12	29	that	that	PRON
admet-3065	12	30	are	be	AUX
admet-3065	12	31	difficult	difficult	ADJ
admet-3065	12	32	or	or	CCONJ
admet-3065	12	33	impossible	impossible	ADJ
admet-3065	12	34	to	to	PART
admet-3065	12	35	treat	treat	VERB
admet-3065	12	36	with	with	ADP
admet-3065	12	37	conventional	conventional	ADJ
admet-3065	12	38	pharmacological	pharmacological	ADJ
admet-3065	12	39	therapies	therapy	NOUN
admet-3065	12	40	[	[	X
admet-3065	12	41	3,4	3,4	NUM
admet-3065	12	42	]	]	PUNCT
admet-3065	12	43	.	.	PUNCT
admet-3065	13	1	the	the	DET
admet-3065	13	2	majority	majority	NOUN
admet-3065	13	3	of	of	ADP
admet-3065	13	4	such	such	ADJ
admet-3065	13	5	diseases	disease	NOUN
admet-3065	13	6	are	be	AUX
admet-3065	13	7	caused	cause	VERB
admet-3065	13	8	by	by	ADP
admet-3065	13	9	genelevel	genelevel	NOUN
admet-3065	13	10	mutations	mutation	NOUN
admet-3065	13	11	,	,	PUNCT
admet-3065	13	12	either	either	CCONJ
admet-3065	13	13	congenital	congenital	ADJ
admet-3065	13	14	or	or	CCONJ
admet-3065	13	15	acquired	acquire	VERB
admet-3065	13	16	over	over	ADP
admet-3065	13	17	time	time	NOUN
admet-3065	13	18	,	,	PUNCT
admet-3065	13	19	that	that	PRON
admet-3065	13	20	remain	remain	VERB
admet-3065	13	21	incurable	incurable	ADJ
admet-3065	13	22	with	with	ADP
admet-3065	13	23	conventional	conventional	ADJ
admet-3065	13	24	drugs	drug	NOUN
admet-3065	13	25	[	[	X
admet-3065	13	26	5	5	NUM
admet-3065	13	27	]	]	PUNCT
admet-3065	13	28	.	.	PUNCT
admet-3065	14	1	therapeutic	therapeutic	ADJ
admet-3065	14	2	technology	technology	NOUN
admet-3065	14	3	advances	advance	NOUN
admet-3065	14	4	have	have	AUX
admet-3065	14	5	enabled	enable	VERB
admet-3065	14	6	the	the	DET
admet-3065	14	7	development	development	NOUN
admet-3065	14	8	of	of	ADP
admet-3065	14	9	strategies	strategy	NOUN
admet-3065	14	10	to	to	PART
admet-3065	14	11	edit	edit	VERB
admet-3065	14	12	,	,	PUNCT
admet-3065	14	13	insert	insert	ADJ
admet-3065	14	14	,	,	PUNCT
admet-3065	14	15	delete	delete	ADJ
admet-3065	14	16	,	,	PUNCT
admet-3065	14	17	replace	replace	NOUN
admet-3065	14	18	,	,	PUNCT
admet-3065	14	19	or	or	CCONJ
admet-3065	14	20	silence	silence	VERB
admet-3065	14	21	individual	individual	ADJ
admet-3065	14	22	genes	gene	NOUN
admet-3065	14	23	[	[	X
admet-3065	14	24	6	6	NUM
admet-3065	14	25	]	]	PUNCT
admet-3065	14	26	.	.	PUNCT
admet-3065	15	1	successful	successful	ADJ
admet-3065	15	2	delivery	delivery	NOUN
admet-3065	15	3	of	of	ADP
admet-3065	15	4	genetic	genetic	ADJ
admet-3065	15	5	material	material	NOUN
admet-3065	15	6	and	and	CCONJ
admet-3065	15	7	editing	edit	VERB
admet-3065	15	8	tools	tool	NOUN
admet-3065	15	9	into	into	ADP
admet-3065	15	10	primary	primary	ADJ
admet-3065	15	11	cells	cell	NOUN
admet-3065	15	12	,	,	PUNCT
admet-3065	15	13	http://doi.org/10.5599/admet.3065	http://doi.org/10.5599/admet.3065	NOUN
admet-3065	15	14	https://pub.iapchem.org/ojs/index.php/admet	https://pub.iapchem.org/ojs/index.php/admet	PROPN
admet-3065	16	1	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-3065	16	2	e.	e.	PROPN
admet-3065	16	3	j.	j.	PROPN
admet-3065	16	4	saleh	saleh	PROPN
admet-3065	16	5	et	et	PROPN
admet-3065	16	6	al	al	PROPN
admet-3065	16	7	.	.	PROPN
admet-3065	16	8	admet	admet	PROPN
admet-3065	16	9	&	&	CCONJ
admet-3065	16	10	dmpk	dmpk	PROPN
admet-3065	16	11	00(0	00(0	PROPN
admet-3065	16	12	)	)	PUNCT
admet-3065	16	13	(	(	PUNCT
admet-3065	16	14	2025	2025	NUM
admet-3065	16	15	)	)	PUNCT
admet-3065	16	16	3065	3065	NUM
admet-3065	16	17	2	2	NUM
admet-3065	16	18	which	which	PRON
admet-3065	16	19	are	be	AUX
admet-3065	16	20	then	then	ADV
admet-3065	16	21	delivered	deliver	VERB
admet-3065	16	22	into	into	ADP
admet-3065	16	23	target	target	NOUN
admet-3065	16	24	organs	organ	NOUN
admet-3065	16	25	,	,	PUNCT
admet-3065	16	26	is	be	AUX
admet-3065	16	27	what	what	PRON
admet-3065	16	28	successful	successful	ADJ
admet-3065	16	29	gene	gene	NOUN
admet-3065	16	30	therapy	therapy	NOUN
admet-3065	16	31	hinges	hinge	VERB
admet-3065	16	32	on	on	ADP
admet-3065	16	33	[	[	X
admet-3065	16	34	7	7	NUM
admet-3065	16	35	]	]	PUNCT
admet-3065	16	36	.	.	PUNCT
admet-3065	17	1	therefore	therefore	ADV
admet-3065	17	2	,	,	PUNCT
admet-3065	17	3	the	the	DET
admet-3065	17	4	selection	selection	NOUN
admet-3065	17	5	of	of	ADP
admet-3065	17	6	an	an	DET
admet-3065	17	7	efficient	efficient	ADJ
admet-3065	17	8	and	and	CCONJ
admet-3065	17	9	safe	safe	ADJ
admet-3065	17	10	method	method	NOUN
admet-3065	17	11	of	of	ADP
admet-3065	17	12	gene	gene	NOUN
admet-3065	17	13	transfer	transfer	NOUN
admet-3065	17	14	is	be	AUX
admet-3065	17	15	paramount	paramount	ADJ
admet-3065	17	16	[	[	X
admet-3065	17	17	8,9	8,9	NUM
admet-3065	17	18	]	]	PUNCT
admet-3065	17	19	.	.	PUNCT
admet-3065	18	1	liposomes	liposome	NOUN
admet-3065	18	2	are	be	AUX
admet-3065	18	3	neutral	neutral	ADJ
admet-3065	18	4	or	or	CCONJ
admet-3065	18	5	charged	charge	VERB
admet-3065	18	6	colloidal	colloidal	NOUN
admet-3065	18	7	drug	drug	NOUN
admet-3065	18	8	and	and	CCONJ
admet-3065	18	9	genetic	genetic	ADJ
admet-3065	18	10	material	material	NOUN
admet-3065	18	11	delivery	delivery	NOUN
admet-3065	18	12	vectors	vector	NOUN
admet-3065	18	13	,	,	PUNCT
admet-3065	18	14	which	which	PRON
admet-3065	18	15	are	be	AUX
admet-3065	18	16	prepared	prepare	VERB
admet-3065	18	17	as	as	ADP
admet-3065	18	18	unilamellar	unilamellar	ADJ
admet-3065	18	19	or	or	CCONJ
admet-3065	18	20	multilamellar	multilamellar	ADJ
admet-3065	18	21	vesicles	vesicle	NOUN
admet-3065	18	22	of	of	ADP
admet-3065	18	23	25	25	NUM
admet-3065	18	24	nm	nm	NOUN
admet-3065	18	25	to	to	ADP
admet-3065	18	26	50	50	NUM
admet-3065	18	27	µm	µm	NOUN
admet-3065	18	28	in	in	ADP
admet-3065	18	29	diameter	diameter	NOUN
admet-3065	18	30	.	.	PUNCT
admet-3065	19	1	they	they	PRON
admet-3065	19	2	primarily	primarily	ADV
admet-3065	19	3	consist	consist	VERB
admet-3065	19	4	of	of	ADP
admet-3065	19	5	phosphorlipids	phosphorlipid	NOUN
admet-3065	19	6	,	,	PUNCT
admet-3065	19	7	cholesterol	cholesterol	NOUN
admet-3065	19	8	,	,	PUNCT
admet-3065	19	9	and	and	CCONJ
admet-3065	19	10	an	an	DET
admet-3065	19	11	interior	interior	ADJ
admet-3065	19	12	aqueous	aqueous	ADJ
admet-3065	19	13	space	space	NOUN
admet-3065	19	14	[	[	X
admet-3065	19	15	10,11	10,11	NOUN
admet-3065	19	16	]	]	X
admet-3065	19	17	.	.	PUNCT
admet-3065	20	1	the	the	DET
admet-3065	20	2	effectiveness	effectiveness	NOUN
admet-3065	20	3	of	of	ADP
admet-3065	20	4	liposome	liposome	NOUN
admet-3065	20	5	-	-	PUNCT
admet-3065	20	6	mediated	mediate	VERB
admet-3065	20	7	transfection	transfection	NOUN
admet-3065	20	8	depends	depend	VERB
admet-3065	20	9	on	on	ADP
admet-3065	20	10	biophysical	biophysical	ADJ
admet-3065	20	11	parameters	parameter	NOUN
admet-3065	20	12	,	,	PUNCT
admet-3065	20	13	including	include	VERB
admet-3065	20	14	vesicle	vesicle	NOUN
admet-3065	20	15	size	size	NOUN
admet-3065	20	16	,	,	PUNCT
admet-3065	20	17	number	number	NOUN
admet-3065	20	18	of	of	ADP
admet-3065	20	19	lipid	lipid	ADJ
admet-3065	20	20	bilayers	bilayer	NOUN
admet-3065	20	21	,	,	PUNCT
admet-3065	20	22	liposome	liposome	VERB
admet-3065	20	23	fluidity	fluidity	NOUN
admet-3065	20	24	,	,	PUNCT
admet-3065	20	25	lipid	lipid	NOUN
admet-3065	20	26	phase	phase	NOUN
admet-3065	20	27	separation	separation	NOUN
admet-3065	20	28	,	,	PUNCT
admet-3065	20	29	and	and	CCONJ
admet-3065	20	30	surface	surface	NOUN
admet-3065	20	31	charge	charge	NOUN
admet-3065	20	32	[	[	X
admet-3065	20	33	12	12	NUM
admet-3065	20	34	]	]	PUNCT
admet-3065	20	35	.	.	PUNCT
admet-3065	21	1	furthermore	furthermore	ADV
admet-3065	21	2	,	,	PUNCT
admet-3065	21	3	every	every	DET
admet-3065	21	4	part	part	NOUN
admet-3065	21	5	of	of	ADP
admet-3065	21	6	the	the	DET
admet-3065	21	7	phospholipid	phospholipid	NOUN
admet-3065	21	8	,	,	PUNCT
admet-3065	21	9	such	such	ADJ
admet-3065	21	10	as	as	ADP
admet-3065	21	11	the	the	DET
admet-3065	21	12	head	head	NOUN
admet-3065	21	13	group	group	NOUN
admet-3065	21	14	,	,	PUNCT
admet-3065	21	15	tail	tail	NOUN
admet-3065	21	16	,	,	PUNCT
admet-3065	21	17	and	and	CCONJ
admet-3065	21	18	body	body	NOUN
admet-3065	21	19	,	,	PUNCT
admet-3065	21	20	plays	play	VERB
admet-3065	21	21	a	a	DET
admet-3065	21	22	significant	significant	ADJ
admet-3065	21	23	role	role	NOUN
admet-3065	21	24	in	in	ADP
admet-3065	21	25	these	these	DET
admet-3065	21	26	factors	factor	NOUN
admet-3065	21	27	[	[	X
admet-3065	21	28	13	13	NUM
admet-3065	21	29	]	]	PUNCT
admet-3065	21	30	.	.	PUNCT
admet-3065	22	1	although	although	SCONJ
admet-3065	22	2	various	various	ADJ
admet-3065	22	3	cationic	cationic	ADJ
admet-3065	22	4	polymers	polymer	NOUN
admet-3065	22	5	-	-	PUNCT
admet-3065	22	6	notably	notably	ADV
admet-3065	22	7	polyethyleneimine	polyethyleneimine	NOUN
admet-3065	22	8	(	(	PUNCT
admet-3065	22	9	pei	pei	PROPN
admet-3065	22	10	)	)	PUNCT
admet-3065	22	11	and	and	CCONJ
admet-3065	22	12	spermine	spermine	NOUN
admet-3065	22	13	demonstrate	demonstrate	VERB
admet-3065	22	14	specific	specific	ADJ
admet-3065	22	15	merits	merit	NOUN
admet-3065	22	16	for	for	ADP
admet-3065	22	17	gene	gene	NOUN
admet-3065	22	18	delivery	delivery	NOUN
admet-3065	22	19	,	,	PUNCT
admet-3065	22	20	cationic	cationic	ADJ
admet-3065	22	21	liposomes	liposome	NOUN
admet-3065	22	22	collectively	collectively	ADV
admet-3065	22	23	offer	offer	VERB
admet-3065	22	24	a	a	DET
admet-3065	22	25	more	more	ADV
admet-3065	22	26	advantageous	advantageous	ADJ
admet-3065	22	27	profile	profile	NOUN
admet-3065	22	28	for	for	ADP
admet-3065	22	29	clinical	clinical	ADJ
admet-3065	22	30	translation	translation	NOUN
admet-3065	22	31	.	.	PUNCT
admet-3065	23	1	pei	pei	PROPN
admet-3065	23	2	is	be	AUX
admet-3065	23	3	widely	widely	ADV
admet-3065	23	4	recognized	recognize	VERB
admet-3065	23	5	for	for	ADP
admet-3065	23	6	its	its	PRON
admet-3065	23	7	potent	potent	ADJ
admet-3065	23	8	"	"	PUNCT
admet-3065	23	9	proton	proton	NOUN
admet-3065	23	10	-	-	PUNCT
admet-3065	23	11	sponge	sponge	NOUN
admet-3065	23	12	"	"	PUNCT
admet-3065	23	13	effect	effect	NOUN
admet-3065	23	14	,	,	PUNCT
admet-3065	23	15	which	which	PRON
admet-3065	23	16	promotes	promote	VERB
admet-3065	23	17	efficient	efficient	ADJ
admet-3065	23	18	endosomal	endosomal	ADJ
admet-3065	23	19	escape	escape	NOUN
admet-3065	23	20	,	,	PUNCT
admet-3065	23	21	a	a	DET
admet-3065	23	22	characteristic	characteristic	NOUN
admet-3065	23	23	we	we	PRON
admet-3065	23	24	have	have	AUX
admet-3065	23	25	effectively	effectively	ADV
admet-3065	23	26	utilized	utilize	VERB
admet-3065	23	27	in	in	ADP
admet-3065	23	28	previous	previous	ADJ
admet-3065	23	29	studies	study	NOUN
admet-3065	23	30	for	for	ADP
admet-3065	23	31	targeted	target	VERB
admet-3065	23	32	drug	drug	NOUN
admet-3065	23	33	delivery	delivery	NOUN
admet-3065	23	34	[	[	X
admet-3065	23	35	14	14	NUM
admet-3065	23	36	]	]	PUNCT
admet-3065	23	37	and	and	CCONJ
admet-3065	23	38	nucleic	nucleic	ADJ
admet-3065	23	39	acid	acid	NOUN
admet-3065	23	40	delivery	delivery	NOUN
admet-3065	24	1	[	[	X
admet-3065	24	2	15	15	NUM
admet-3065	24	3	]	]	PUNCT
admet-3065	24	4	.	.	PUNCT
admet-3065	25	1	similarly	similarly	ADV
admet-3065	25	2	,	,	PUNCT
admet-3065	25	3	spermine	spermine	NOUN
admet-3065	25	4	is	be	AUX
admet-3065	25	5	effective	effective	ADJ
admet-3065	25	6	in	in	ADP
admet-3065	25	7	our	our	PRON
admet-3065	25	8	earlier	early	ADJ
admet-3065	25	9	work	work	NOUN
admet-3065	25	10	,	,	PUNCT
admet-3065	25	11	facilitating	facilitate	VERB
admet-3065	25	12	gene	gene	NOUN
admet-3065	25	13	transfer	transfer	NOUN
admet-3065	25	14	with	with	ADP
admet-3065	25	15	appreciable	appreciable	ADJ
admet-3065	25	16	efficiency	efficiency	NOUN
admet-3065	25	17	owing	owe	VERB
admet-3065	25	18	to	to	ADP
admet-3065	25	19	its	its	PRON
admet-3065	25	20	strong	strong	ADJ
admet-3065	25	21	nucleic	nucleic	ADJ
admet-3065	25	22	acid	acid	NOUN
admet-3065	25	23	condensation	condensation	NOUN
admet-3065	25	24	capacity	capacity	NOUN
admet-3065	25	25	[	[	X
admet-3065	25	26	16	16	NUM
admet-3065	25	27	]	]	PUNCT
admet-3065	25	28	.	.	PUNCT
admet-3065	26	1	in	in	ADP
admet-3065	26	2	contrast	contrast	NOUN
admet-3065	26	3	,	,	PUNCT
admet-3065	26	4	cationic	cationic	ADJ
admet-3065	26	5	liposomes	liposome	NOUN
admet-3065	26	6	are	be	AUX
admet-3065	26	7	generally	generally	ADV
admet-3065	26	8	favoured	favour	VERB
admet-3065	26	9	due	due	ADP
admet-3065	26	10	to	to	ADP
admet-3065	26	11	their	their	PRON
admet-3065	26	12	superior	superior	ADJ
admet-3065	26	13	biocompatibility	biocompatibility	NOUN
admet-3065	26	14	,	,	PUNCT
admet-3065	26	15	reduced	reduce	VERB
admet-3065	26	16	cytotoxicity	cytotoxicity	NOUN
admet-3065	26	17	,	,	PUNCT
admet-3065	26	18	formulation	formulation	NOUN
admet-3065	26	19	simplicity	simplicity	NOUN
admet-3065	26	20	,	,	PUNCT
admet-3065	26	21	and	and	CCONJ
admet-3065	26	22	consistently	consistently	ADV
admet-3065	26	23	higher	high	ADJ
admet-3065	26	24	transfection	transfection	NOUN
admet-3065	26	25	efficiency	efficiency	NOUN
admet-3065	26	26	-	-	PUNCT
admet-3065	26	27	attributes	attribute	NOUN
admet-3065	26	28	that	that	PRON
admet-3065	26	29	collectively	collectively	ADV
admet-3065	26	30	underscore	underscore	VERB
admet-3065	26	31	their	their	PRON
admet-3065	26	32	broader	broad	ADJ
admet-3065	26	33	utility	utility	NOUN
admet-3065	26	34	and	and	CCONJ
admet-3065	26	35	popularity	popularity	NOUN
admet-3065	26	36	in	in	ADP
admet-3065	26	37	gene	gene	NOUN
admet-3065	26	38	therapy	therapy	NOUN
admet-3065	26	39	applications	application	NOUN
admet-3065	26	40	[	[	X
admet-3065	26	41	17	17	NUM
admet-3065	26	42	]	]	PUNCT
admet-3065	26	43	.	.	PUNCT
admet-3065	27	1	on	on	ADP
admet-3065	27	2	the	the	DET
admet-3065	27	3	other	other	ADJ
admet-3065	27	4	hand	hand	NOUN
admet-3065	27	5	,	,	PUNCT
admet-3065	27	6	it	it	PRON
admet-3065	27	7	’s	’	VERB
admet-3065	27	8	still	still	ADV
admet-3065	27	9	less	less	ADV
admet-3065	27	10	effective	effective	ADJ
admet-3065	27	11	than	than	ADP
admet-3065	27	12	viral	viral	ADJ
admet-3065	27	13	vectors	vector	NOUN
admet-3065	27	14	[	[	X
admet-3065	27	15	18	18	NUM
admet-3065	27	16	]	]	PUNCT
admet-3065	27	17	.	.	PUNCT
admet-3065	28	1	liposomes	liposome	NOUN
admet-3065	28	2	are	be	AUX
admet-3065	28	3	more	more	ADV
admet-3065	28	4	effective	effective	ADJ
admet-3065	28	5	and	and	CCONJ
admet-3065	28	6	popular	popular	ADJ
admet-3065	28	7	than	than	ADP
admet-3065	28	8	other	other	ADJ
admet-3065	28	9	chemical	chemical	NOUN
admet-3065	28	10	-	-	PUNCT
admet-3065	28	11	based	base	VERB
admet-3065	28	12	vectors	vector	NOUN
admet-3065	28	13	for	for	ADP
admet-3065	28	14	effective	effective	ADJ
admet-3065	28	15	gene	gene	NOUN
admet-3065	28	16	delivery	delivery	NOUN
admet-3065	28	17	and	and	CCONJ
admet-3065	28	18	gene	gene	NOUN
admet-3065	28	19	therapy	therapy	NOUN
admet-3065	28	20	[	[	X
admet-3065	28	21	19	19	NUM
admet-3065	28	22	]	]	PUNCT
admet-3065	28	23	.	.	PUNCT
admet-3065	29	1	gene	gene	NOUN
admet-3065	29	2	delivery	delivery	NOUN
admet-3065	29	3	methods	method	NOUN
admet-3065	29	4	can	can	AUX
admet-3065	29	5	be	be	AUX
admet-3065	29	6	classified	classify	VERB
admet-3065	29	7	into	into	ADP
admet-3065	29	8	viral	viral	ADJ
admet-3065	29	9	,	,	PUNCT
admet-3065	29	10	physical	physical	ADJ
admet-3065	29	11	,	,	PUNCT
admet-3065	29	12	and	and	CCONJ
admet-3065	29	13	chemical	chemical	NOUN
admet-3065	29	14	strategies	strategy	NOUN
admet-3065	29	15	[	[	X
admet-3065	29	16	20	20	NUM
admet-3065	29	17	]	]	PUNCT
admet-3065	29	18	.	.	PUNCT
admet-3065	30	1	viral	viral	ADJ
admet-3065	30	2	vectors	vector	NOUN
admet-3065	30	3	,	,	PUNCT
admet-3065	30	4	developed	develop	VERB
admet-3065	30	5	by	by	ADP
admet-3065	30	6	replacing	replace	VERB
admet-3065	30	7	pathogenic	pathogenic	ADJ
admet-3065	30	8	genes	gene	NOUN
admet-3065	30	9	in	in	ADP
admet-3065	30	10	viruses	virus	NOUN
admet-3065	30	11	with	with	ADP
admet-3065	30	12	therapeutic	therapeutic	ADJ
admet-3065	30	13	genes	gene	NOUN
admet-3065	30	14	,	,	PUNCT
admet-3065	30	15	remain	remain	VERB
admet-3065	30	16	widely	widely	ADV
admet-3065	30	17	used	use	VERB
admet-3065	30	18	due	due	ADP
admet-3065	30	19	to	to	ADP
admet-3065	30	20	their	their	PRON
admet-3065	30	21	naturally	naturally	ADV
admet-3065	30	22	evolved	evolve	VERB
admet-3065	30	23	genome	genome	NOUN
admet-3065	30	24	-	-	PUNCT
admet-3065	30	25	delivery	delivery	NOUN
admet-3065	30	26	properties	property	NOUN
admet-3065	30	27	[	[	X
admet-3065	30	28	21	21	NUM
admet-3065	30	29	]	]	PUNCT
admet-3065	30	30	.	.	PUNCT
admet-3065	31	1	both	both	PRON
admet-3065	31	2	of	of	ADP
admet-3065	31	3	these	these	DET
admet-3065	31	4	vectors	vector	NOUN
admet-3065	31	5	,	,	PUNCT
admet-3065	31	6	chemical	chemical	NOUN
admet-3065	31	7	and	and	CCONJ
admet-3065	31	8	viral	viral	ADJ
admet-3065	31	9	,	,	PUNCT
admet-3065	31	10	can	can	AUX
admet-3065	31	11	be	be	AUX
admet-3065	31	12	combined	combine	VERB
admet-3065	31	13	with	with	ADP
admet-3065	31	14	various	various	ADJ
admet-3065	31	15	physical	physical	ADJ
admet-3065	31	16	methods	method	NOUN
admet-3065	31	17	,	,	PUNCT
admet-3065	31	18	such	such	ADJ
admet-3065	31	19	as	as	ADP
admet-3065	31	20	microinjection	microinjection	NOUN
admet-3065	31	21	,	,	PUNCT
admet-3065	31	22	magnetofection	magnetofection	NOUN
admet-3065	31	23	,	,	PUNCT
admet-3065	31	24	mechanical	mechanical	ADJ
admet-3065	31	25	massage	massage	NOUN
admet-3065	31	26	,	,	PUNCT
admet-3065	31	27	hydrodynamic	hydrodynamic	ADJ
admet-3065	31	28	injection	injection	NOUN
admet-3065	31	29	,	,	PUNCT
admet-3065	31	30	sonoporation	sonoporation	NOUN
admet-3065	31	31	,	,	PUNCT
admet-3065	31	32	laser	laser	NOUN
admet-3065	31	33	-	-	PUNCT
admet-3065	31	34	mediated	mediate	VERB
admet-3065	31	35	delivery	delivery	NOUN
admet-3065	31	36	,	,	PUNCT
admet-3065	31	37	biolistics	biolistic	NOUN
admet-3065	31	38	,	,	PUNCT
admet-3065	31	39	electroporation	electroporation	NOUN
admet-3065	31	40	,	,	PUNCT
admet-3065	31	41	thermal	thermal	ADJ
admet-3065	31	42	methods	method	NOUN
admet-3065	31	43	,	,	PUNCT
admet-3065	31	44	and	and	CCONJ
admet-3065	31	45	ultrasound	ultrasound	NOUN
admet-3065	31	46	-	-	PUNCT
admet-3065	31	47	assisted	assist	VERB
admet-3065	31	48	delivery	delivery	NOUN
admet-3065	31	49	,	,	PUNCT
admet-3065	31	50	which	which	PRON
admet-3065	31	51	we	we	PRON
admet-3065	31	52	will	will	AUX
admet-3065	31	53	discuss	discuss	VERB
admet-3065	31	54	in	in	ADP
admet-3065	31	55	the	the	DET
admet-3065	31	56	continuation	continuation	NOUN
admet-3065	31	57	of	of	ADP
admet-3065	31	58	this	this	DET
admet-3065	31	59	review	review	NOUN
admet-3065	32	1	[	[	X
admet-3065	32	2	22	22	NUM
admet-3065	32	3	]	]	PUNCT
admet-3065	32	4	.	.	PUNCT
admet-3065	33	1	gene	gene	NOUN
admet-3065	33	2	therapy	therapy	NOUN
admet-3065	33	3	gene	gene	NOUN
admet-3065	33	4	therapy	therapy	NOUN
admet-3065	33	5	is	be	AUX
admet-3065	33	6	a	a	DET
admet-3065	33	7	milestone	milestone	NOUN
admet-3065	33	8	in	in	ADP
admet-3065	33	9	the	the	DET
admet-3065	33	10	ongoing	ongoing	ADJ
admet-3065	33	11	quest	quest	NOUN
admet-3065	33	12	to	to	PART
admet-3065	33	13	cure	cure	VERB
admet-3065	33	14	,	,	PUNCT
admet-3065	33	15	and	and	CCONJ
admet-3065	33	16	even	even	ADV
admet-3065	33	17	eliminate	eliminate	VERB
admet-3065	33	18	,	,	PUNCT
admet-3065	33	19	many	many	ADJ
admet-3065	33	20	diseases	disease	NOUN
admet-3065	33	21	[	[	X
admet-3065	33	22	23,24	23,24	NUM
admet-3065	33	23	]	]	PUNCT
admet-3065	33	24	.	.	PUNCT
admet-3065	34	1	gene	gene	NOUN
admet-3065	34	2	therapy	therapy	NOUN
admet-3065	34	3	encompasses	encompass	VERB
admet-3065	34	4	some	some	DET
admet-3065	34	5	general	general	ADJ
admet-3065	34	6	strategies	strategy	NOUN
admet-3065	34	7	:	:	PUNCT
admet-3065	34	8	gene	gene	NOUN
admet-3065	34	9	silencing	silencing	NOUN
admet-3065	34	10	,	,	PUNCT
admet-3065	34	11	gene	gene	NOUN
admet-3065	34	12	replacement	replacement	NOUN
admet-3065	34	13	,	,	PUNCT
admet-3065	34	14	and	and	CCONJ
admet-3065	34	15	gene	gene	NOUN
admet-3065	34	16	editing	edit	VERB
admet-3065	34	17	[	[	X
admet-3065	34	18	24,25	24,25	NUM
admet-3065	34	19	]	]	PUNCT
admet-3065	34	20	.	.	PUNCT
admet-3065	35	1	gene	gene	NOUN
admet-3065	35	2	silencing	silence	VERB
admet-3065	35	3	uses	use	VERB
admet-3065	35	4	small	small	ADJ
admet-3065	35	5	interfering	interfere	VERB
admet-3065	35	6	rna	rna	NOUN
admet-3065	35	7	(	(	PUNCT
admet-3065	35	8	sirna	sirna	PROPN
admet-3065	35	9	)	)	PUNCT
admet-3065	35	10	,	,	PUNCT
admet-3065	35	11	short	short	ADJ
admet-3065	35	12	hairpin	hairpin	NOUN
admet-3065	35	13	rna	rna	NOUN
admet-3065	35	14	(	(	PUNCT
admet-3065	35	15	shrna	shrna	NOUN
admet-3065	35	16	)	)	PUNCT
admet-3065	35	17	,	,	PUNCT
admet-3065	35	18	and	and	CCONJ
admet-3065	35	19	microrna	microrna	PROPN
admet-3065	35	20	(	(	PUNCT
admet-3065	35	21	mirna	mirna	PROPN
admet-3065	35	22	)	)	PUNCT
admet-3065	35	23	to	to	PART
admet-3065	35	24	reduce	reduce	VERB
admet-3065	35	25	gene	gene	NOUN
admet-3065	35	26	expression	expression	NOUN
admet-3065	35	27	at	at	ADP
admet-3065	35	28	the	the	DET
admet-3065	35	29	mrna	mrna	NOUN
admet-3065	35	30	level	level	NOUN
admet-3065	36	1	[	[	X
admet-3065	36	2	24,26	24,26	NOUN
admet-3065	36	3	]	]	PUNCT
admet-3065	36	4	.	.	PUNCT
admet-3065	37	1	gene	gene	NOUN
admet-3065	37	2	replacement	replacement	NOUN
admet-3065	37	3	therapy	therapy	NOUN
admet-3065	37	4	delivers	deliver	VERB
admet-3065	37	5	functional	functional	ADJ
admet-3065	37	6	genes	gene	NOUN
admet-3065	37	7	,	,	PUNCT
admet-3065	37	8	typically	typically	ADV
admet-3065	37	9	via	via	ADP
admet-3065	37	10	plasmids	plasmid	NOUN
admet-3065	37	11	or	or	CCONJ
admet-3065	37	12	viral	viral	ADJ
admet-3065	37	13	vectors	vector	NOUN
admet-3065	37	14	,	,	PUNCT
admet-3065	37	15	to	to	PART
admet-3065	37	16	supplement	supplement	VERB
admet-3065	37	17	or	or	CCONJ
admet-3065	37	18	replace	replace	VERB
admet-3065	37	19	protein	protein	NOUN
admet-3065	37	20	expression	expression	NOUN
admet-3065	37	21	[	[	X
admet-3065	37	22	27	27	NUM
admet-3065	37	23	]	]	PUNCT
admet-3065	37	24	.	.	PUNCT
admet-3065	38	1	in	in	ADP
admet-3065	38	2	addition	addition	NOUN
admet-3065	38	3	,	,	PUNCT
admet-3065	38	4	gene	gene	NOUN
admet-3065	38	5	editing	edit	VERB
admet-3065	38	6	directly	directly	ADV
admet-3065	38	7	targets	target	VERB
admet-3065	38	8	specific	specific	ADJ
admet-3065	38	9	mutations	mutation	NOUN
admet-3065	38	10	using	use	VERB
admet-3065	38	11	engineered	engineer	VERB
admet-3065	38	12	nucleases	nuclease	NOUN
admet-3065	38	13	,	,	PUNCT
admet-3065	38	14	such	such	ADJ
admet-3065	38	15	as	as	ADP
admet-3065	38	16	zinc	zinc	NOUN
admet-3065	38	17	finger	finger	NOUN
admet-3065	38	18	nucleases	nuclease	NOUN
admet-3065	38	19	(	(	PUNCT
admet-3065	38	20	zfns	zfns	NOUN
admet-3065	38	21	)	)	PUNCT
admet-3065	38	22	,	,	PUNCT
admet-3065	38	23	transcription	transcription	NOUN
admet-3065	38	24	activator	activator	NOUN
admet-3065	38	25	-	-	PUNCT
admet-3065	38	26	like	like	ADJ
admet-3065	38	27	effector	effector	NOUN
admet-3065	38	28	nucleases	nuclease	NOUN
admet-3065	38	29	(	(	PUNCT
admet-3065	38	30	talens	talen	NOUN
admet-3065	38	31	)	)	PUNCT
admet-3065	38	32	,	,	PUNCT
admet-3065	38	33	and	and	CCONJ
admet-3065	38	34	the	the	DET
admet-3065	38	35	crispr	crispr	ADJ
admet-3065	38	36	/	/	SYM
admet-3065	38	37	cas	cas	NOUN
admet-3065	38	38	system	system	NOUN
admet-3065	38	39	[	[	X
admet-3065	38	40	28	28	NUM
admet-3065	38	41	]	]	PUNCT
admet-3065	38	42	.	.	PUNCT
admet-3065	39	1	in	in	ADP
admet-3065	39	2	continuation	continuation	NOUN
admet-3065	39	3	,	,	PUNCT
admet-3065	39	4	for	for	ADP
admet-3065	39	5	effective	effective	ADJ
admet-3065	39	6	delivery	delivery	NOUN
admet-3065	39	7	of	of	ADP
admet-3065	39	8	these	these	DET
admet-3065	39	9	proteins	protein	NOUN
admet-3065	39	10	into	into	ADP
admet-3065	39	11	target	target	NOUN
admet-3065	39	12	cells	cell	NOUN
admet-3065	39	13	,	,	PUNCT
admet-3065	39	14	vectors	vector	NOUN
admet-3065	39	15	are	be	AUX
admet-3065	39	16	required	require	VERB
admet-3065	39	17	to	to	PART
admet-3065	39	18	protect	protect	VERB
admet-3065	39	19	them	they	PRON
admet-3065	39	20	from	from	ADP
admet-3065	39	21	enzymatic	enzymatic	ADJ
admet-3065	39	22	degradation	degradation	NOUN
admet-3065	39	23	and	and	CCONJ
admet-3065	39	24	immune	immune	ADJ
admet-3065	39	25	cell	cell	NOUN
admet-3065	39	26	recognition	recognition	NOUN
admet-3065	40	1	[	[	X
admet-3065	40	2	29	29	NUM
admet-3065	40	3	]	]	PUNCT
admet-3065	40	4	.	.	PUNCT
admet-3065	41	1	gene	gene	NOUN
admet-3065	41	2	therapy	therapy	NOUN
admet-3065	41	3	has	have	AUX
admet-3065	41	4	been	be	AUX
admet-3065	41	5	explored	explore	VERB
admet-3065	41	6	for	for	ADP
admet-3065	41	7	a	a	DET
admet-3065	41	8	wide	wide	ADJ
admet-3065	41	9	variety	variety	NOUN
admet-3065	41	10	of	of	ADP
admet-3065	41	11	diseases	disease	NOUN
admet-3065	41	12	,	,	PUNCT
admet-3065	41	13	but	but	CCONJ
admet-3065	41	14	the	the	DET
admet-3065	41	15	safe	safe	ADJ
admet-3065	41	16	and	and	CCONJ
admet-3065	41	17	effective	effective	ADJ
admet-3065	41	18	delivery	delivery	NOUN
admet-3065	41	19	of	of	ADP
admet-3065	41	20	genetic	genetic	ADJ
admet-3065	41	21	material	material	NOUN
admet-3065	41	22	remains	remain	VERB
admet-3065	41	23	the	the	DET
admet-3065	41	24	central	central	ADJ
admet-3065	41	25	challenge	challenge	NOUN
admet-3065	42	1	[	[	X
admet-3065	42	2	25	25	NUM
admet-3065	42	3	]	]	PUNCT
admet-3065	42	4	.	.	PUNCT
admet-3065	43	1	to	to	PART
admet-3065	43	2	be	be	AUX
admet-3065	43	3	effective	effective	ADJ
admet-3065	43	4	in	in	ADP
admet-3065	43	5	gene	gene	NOUN
admet-3065	43	6	therapy	therapy	NOUN
admet-3065	43	7	,	,	PUNCT
admet-3065	43	8	the	the	DET
admet-3065	43	9	delivery	delivery	NOUN
admet-3065	43	10	vector	vector	NOUN
admet-3065	43	11	must	must	AUX
admet-3065	43	12	protect	protect	VERB
admet-3065	43	13	dna	dna	PROPN
admet-3065	43	14	molecules	molecule	NOUN
admet-3065	43	15	,	,	PUNCT
admet-3065	43	16	hydrophilic	hydrophilic	ADJ
admet-3065	43	17	and	and	CCONJ
admet-3065	43	18	physiologically	physiologically	ADV
admet-3065	43	19	large	large	ADJ
admet-3065	43	20	with	with	ADP
admet-3065	43	21	their	their	PRON
admet-3065	43	22	negatively	negatively	ADV
admet-3065	43	23	charged	charge	VERB
admet-3065	43	24	phosphate	phosphate	NOUN
admet-3065	43	25	backbone	backbone	NOUN
admet-3065	43	26	,	,	PUNCT
admet-3065	43	27	against	against	ADP
admet-3065	43	28	nucleases	nuclease	NOUN
admet-3065	43	29	for	for	ADP
admet-3065	43	30	degradation	degradation	NOUN
admet-3065	43	31	and	and	CCONJ
admet-3065	43	32	enhance	enhance	VERB
admet-3065	43	33	cellular	cellular	ADJ
admet-3065	43	34	uptake	uptake	NOUN
admet-3065	43	35	[	[	X
admet-3065	43	36	30	30	NUM
admet-3065	43	37	]	]	PUNCT
admet-3065	43	38	.	.	PUNCT
admet-3065	44	1	delivery	delivery	NOUN
admet-3065	44	2	systems	system	NOUN
admet-3065	44	3	,	,	PUNCT
admet-3065	44	4	particularly	particularly	ADV
admet-3065	44	5	vectors	vector	NOUN
admet-3065	44	6	,	,	PUNCT
admet-3065	44	7	are	be	AUX
admet-3065	44	8	required	require	VERB
admet-3065	44	9	because	because	SCONJ
admet-3065	44	10	naked	naked	ADJ
admet-3065	44	11	dna	dna	NOUN
admet-3065	44	12	can	can	AUX
admet-3065	44	13	not	not	PART
admet-3065	44	14	effectively	effectively	ADV
admet-3065	44	15	penetrate	penetrate	VERB
admet-3065	44	16	cell	cell	NOUN
admet-3065	44	17	membranes	membrane	NOUN
admet-3065	44	18	or	or	CCONJ
admet-3065	44	19	resist	resist	VERB
admet-3065	44	20	enzymatic	enzymatic	ADJ
admet-3065	44	21	degradation	degradation	NOUN
admet-3065	44	22	[	[	X
admet-3065	44	23	31	31	NUM
admet-3065	44	24	]	]	PUNCT
admet-3065	44	25	.	.	PUNCT
admet-3065	45	1	admet	admet	PROPN
admet-3065	45	2	&	&	CCONJ
admet-3065	45	3	dmpk	dmpk	PROPN
admet-3065	45	4	00(0	00(0	PROPN
admet-3065	45	5	)	)	PUNCT
admet-3065	45	6	(	(	PUNCT
admet-3065	45	7	2025	2025	NUM
admet-3065	45	8	)	)	PUNCT
admet-3065	45	9	3065	3065	NUM
admet-3065	45	10	liposome	liposome	NOUN
admet-3065	45	11	-	-	PUNCT
admet-3065	45	12	mediated	mediate	VERB
admet-3065	45	13	gene	gene	NOUN
admet-3065	45	14	delivery	delivery	NOUN
admet-3065	45	15	doi	doi	NOUN
admet-3065	45	16	:	:	PUNCT
admet-3065	45	17	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	45	18	3	3	NUM
admet-3065	45	19	gene	gene	NOUN
admet-3065	45	20	delivery	delivery	NOUN
admet-3065	45	21	barriers	barrier	VERB
admet-3065	45	22	one	one	NUM
admet-3065	45	23	of	of	ADP
admet-3065	45	24	the	the	DET
admet-3065	45	25	most	most	ADV
admet-3065	45	26	noticeable	noticeable	ADJ
admet-3065	45	27	aspects	aspect	NOUN
admet-3065	45	28	of	of	ADP
admet-3065	45	29	an	an	DET
admet-3065	45	30	effective	effective	ADJ
admet-3065	45	31	gene	gene	NOUN
admet-3065	45	32	therapy	therapy	NOUN
admet-3065	45	33	is	be	AUX
admet-3065	45	34	the	the	DET
admet-3065	45	35	bypassing	bypassing	NOUN
admet-3065	45	36	of	of	ADP
admet-3065	45	37	gene	gene	NOUN
admet-3065	45	38	delivery	delivery	NOUN
admet-3065	45	39	barriers	barrier	NOUN
admet-3065	45	40	,	,	PUNCT
admet-3065	45	41	which	which	PRON
admet-3065	45	42	can	can	AUX
admet-3065	45	43	be	be	AUX
admet-3065	45	44	categorized	categorize	VERB
admet-3065	45	45	into	into	ADP
admet-3065	45	46	intracellular	intracellular	ADJ
admet-3065	45	47	and	and	CCONJ
admet-3065	45	48	extracellular	extracellular	ADJ
admet-3065	45	49	barriers	barrier	NOUN
admet-3065	45	50	[	[	X
admet-3065	45	51	32	32	NUM
admet-3065	45	52	]	]	PUNCT
admet-3065	45	53	,	,	PUNCT
admet-3065	45	54	as	as	SCONJ
admet-3065	45	55	shown	show	VERB
admet-3065	45	56	in	in	ADP
admet-3065	45	57	table	table	NOUN
admet-3065	45	58	1	1	NUM
admet-3065	45	59	.	.	PUNCT
admet-3065	46	1	the	the	DET
admet-3065	46	2	cell	cell	NOUN
admet-3065	46	3	membrane	membrane	NOUN
admet-3065	46	4	is	be	AUX
admet-3065	46	5	a	a	DET
admet-3065	46	6	prominent	prominent	ADJ
admet-3065	46	7	intracellular	intracellular	ADJ
admet-3065	46	8	barrier	barrier	NOUN
admet-3065	46	9	.	.	PUNCT
admet-3065	47	1	it	it	PRON
admet-3065	47	2	consists	consist	VERB
admet-3065	47	3	of	of	ADP
admet-3065	47	4	different	different	ADJ
admet-3065	47	5	proteins	protein	NOUN
admet-3065	47	6	,	,	PUNCT
admet-3065	47	7	phospholipids	phospholipid	NOUN
admet-3065	47	8	,	,	PUNCT
admet-3065	47	9	cholesterol	cholesterol	NOUN
admet-3065	47	10	,	,	PUNCT
admet-3065	47	11	and	and	CCONJ
admet-3065	47	12	saccharides	saccharide	NOUN
admet-3065	47	13	that	that	PRON
admet-3065	47	14	play	play	VERB
admet-3065	47	15	a	a	DET
admet-3065	47	16	significant	significant	ADJ
admet-3065	47	17	role	role	NOUN
admet-3065	47	18	in	in	ADP
admet-3065	47	19	preventing	prevent	VERB
admet-3065	47	20	exogenous	exogenous	ADJ
admet-3065	47	21	nucleic	nucleic	ADJ
admet-3065	47	22	acids	acid	NOUN
admet-3065	47	23	from	from	ADP
admet-3065	47	24	entering	enter	VERB
admet-3065	47	25	the	the	DET
admet-3065	47	26	cell	cell	NOUN
admet-3065	47	27	membrane	membrane	NOUN
admet-3065	47	28	[	[	X
admet-3065	47	29	33	33	NUM
admet-3065	47	30	]	]	PUNCT
admet-3065	47	31	.	.	PUNCT
admet-3065	48	1	endocytosis	endocytosis	NOUN
admet-3065	48	2	is	be	AUX
admet-3065	48	3	one	one	NUM
admet-3065	48	4	of	of	ADP
admet-3065	48	5	the	the	DET
admet-3065	48	6	most	most	ADV
admet-3065	48	7	effective	effective	ADJ
admet-3065	48	8	mechanisms	mechanism	NOUN
admet-3065	48	9	for	for	ADP
admet-3065	48	10	cellular	cellular	ADJ
admet-3065	48	11	uptake	uptake	NOUN
admet-3065	48	12	[	[	X
admet-3065	48	13	34	34	NUM
admet-3065	48	14	]	]	PUNCT
admet-3065	48	15	.	.	PUNCT
admet-3065	49	1	however	however	ADV
admet-3065	49	2	,	,	PUNCT
admet-3065	49	3	following	follow	VERB
admet-3065	49	4	endocytosis	endocytosis	NOUN
admet-3065	49	5	,	,	PUNCT
admet-3065	49	6	lysosomes	lysosome	NOUN
admet-3065	49	7	,	,	PUNCT
admet-3065	49	8	which	which	PRON
admet-3065	49	9	are	be	AUX
admet-3065	49	10	charged	charge	VERB
admet-3065	49	11	with	with	ADP
admet-3065	49	12	hydrolytic	hydrolytic	ADJ
admet-3065	49	13	enzymes	enzyme	NOUN
admet-3065	49	14	,	,	PUNCT
admet-3065	49	15	pose	pose	VERB
admet-3065	49	16	another	another	DET
admet-3065	49	17	barrier	barrier	NOUN
admet-3065	49	18	by	by	ADP
admet-3065	49	19	degrading	degrade	VERB
admet-3065	49	20	the	the	DET
admet-3065	49	21	internalized	internalized	ADJ
admet-3065	49	22	genetic	genetic	ADJ
admet-3065	49	23	cargo	cargo	NOUN
admet-3065	49	24	[	[	X
admet-3065	49	25	35	35	NUM
admet-3065	49	26	]	]	PUNCT
admet-3065	49	27	.	.	PUNCT
admet-3065	50	1	table	table	NOUN
admet-3065	50	2	1	1	NUM
admet-3065	50	3	.	.	X
admet-3065	50	4	intracellular	intracellular	ADJ
admet-3065	50	5	and	and	CCONJ
admet-3065	50	6	extracellular	extracellular	ADJ
admet-3065	50	7	barriers	barrier	NOUN
admet-3065	50	8	affecting	affect	VERB
admet-3065	50	9	nucleic	nucleic	ADJ
admet-3065	50	10	acid	acid	NOUN
admet-3065	50	11	delivery	delivery	NOUN
admet-3065	50	12	.	.	PUNCT
admet-3065	51	1	type	type	NOUN
admet-3065	51	2	barrier	barrier	NOUN
admet-3065	51	3	description	description	NOUN
admet-3065	51	4	intracellular	intracellular	ADJ
admet-3065	51	5	cell	cell	NOUN
admet-3065	51	6	membrane	membrane	NOUN
admet-3065	51	7	prevents	prevent	VERB
admet-3065	51	8	entry	entry	NOUN
admet-3065	51	9	of	of	ADP
admet-3065	51	10	dna	dna	PROPN
admet-3065	51	11	due	due	ADJ
admet-3065	51	12	to	to	PART
admet-3065	51	13	charge	charge	VERB
admet-3065	51	14	and	and	CCONJ
admet-3065	51	15	size	size	NOUN
admet-3065	51	16	[	[	X
admet-3065	51	17	33	33	NUM
admet-3065	51	18	]	]	X
admet-3065	51	19	intracellular	intracellular	ADJ
admet-3065	51	20	nucleus	nucleus	ADJ
admet-3065	51	21	entry	entry	NOUN
admet-3065	51	22	cargo	cargo	NOUN
admet-3065	51	23	must	must	AUX
admet-3065	51	24	have	have	VERB
admet-3065	51	25	an	an	DET
admet-3065	51	26	importin	importin	NOUN
admet-3065	51	27	to	to	PART
admet-3065	51	28	be	be	AUX
admet-3065	51	29	able	able	ADJ
admet-3065	51	30	to	to	PART
admet-3065	51	31	enter	enter	VERB
admet-3065	51	32	the	the	DET
admet-3065	51	33	nucleus	nucleus	NOUN
admet-3065	52	1	[	[	X
admet-3065	52	2	36	36	NUM
admet-3065	52	3	]	]	X
admet-3065	52	4	intracellular	intracellular	ADJ
admet-3065	52	5	lysosomal	lysosomal	ADJ
admet-3065	52	6	degradation	degradation	NOUN
admet-3065	52	7	degrades	degrade	VERB
admet-3065	52	8	internalized	internalize	VERB
admet-3065	52	9	genetic	genetic	ADJ
admet-3065	52	10	material	material	NOUN
admet-3065	52	11	[	[	X
admet-3065	52	12	35	35	NUM
admet-3065	52	13	]	]	X
admet-3065	52	14	extracellular	extracellular	ADJ
admet-3065	52	15	circulating	circulate	VERB
admet-3065	52	16	stability	stability	NOUN
admet-3065	52	17	serum	serum	NOUN
admet-3065	52	18	nucleases	nuclease	NOUN
admet-3065	52	19	(	(	PUNCT
admet-3065	52	20	e.g.	e.g.	ADV
admet-3065	52	21	dnase	dnase	NOUN
admet-3065	52	22	i	i	PRON
admet-3065	52	23	)	)	PUNCT
admet-3065	52	24	degrade	degrade	VERB
admet-3065	52	25	naked	naked	ADJ
admet-3065	52	26	dna	dna	NOUN
admet-3065	52	27	.	.	PUNCT
admet-3065	53	1	stabilization	stabilization	NOUN
admet-3065	53	2	:	:	PUNCT
admet-3065	53	3	pegylation	pegylation	NOUN
admet-3065	53	4	,	,	PUNCT
admet-3065	53	5	nanoparticle	nanoparticle	NOUN
admet-3065	53	6	encapsulation	encapsulation	NOUN
admet-3065	54	1	[	[	X
admet-3065	54	2	37	37	NUM
admet-3065	54	3	]	]	X
admet-3065	54	4	extracellular	extracellular	ADJ
admet-3065	54	5	administration	administration	NOUN
admet-3065	54	6	route	route	NOUN
admet-3065	54	7	challenges	challenge	NOUN
admet-3065	54	8	vary	vary	VERB
admet-3065	54	9	by	by	ADP
admet-3065	54	10	route	route	NOUN
admet-3065	54	11	(	(	PUNCT
admet-3065	54	12	e.g.	e.g.	ADV
admet-3065	54	13	iv	iv	NUM
admet-3065	54	14	:	:	PUNCT
admet-3065	54	15	serum	serum	NOUN
admet-3065	54	16	clearance	clearance	NOUN
admet-3065	54	17	;	;	PUNCT
admet-3065	54	18	i	i	PRON
admet-3065	54	19	m	m	VERB
admet-3065	54	20	:	:	PUNCT
admet-3065	54	21	tissue	tissue	NOUN
admet-3065	54	22	diffusion	diffusion	NOUN
admet-3065	54	23	;	;	PUNCT
admet-3065	54	24	oral	oral	ADJ
admet-3065	54	25	:	:	PUNCT
admet-3065	54	26	gi	gi	NOUN
admet-3065	54	27	degradation	degradation	NOUN
admet-3065	54	28	)	)	PUNCT
admet-3065	55	1	[	[	X
admet-3065	55	2	30	30	NUM
admet-3065	55	3	]	]	X
admet-3065	55	4	extracellular	extracellular	ADJ
admet-3065	55	5	immune	immune	ADJ
admet-3065	55	6	system	system	NOUN
admet-3065	55	7	recognizes	recognize	VERB
admet-3065	55	8	and	and	CCONJ
admet-3065	55	9	eliminates	eliminate	VERB
admet-3065	55	10	foreign	foreign	ADJ
admet-3065	55	11	particles	particle	NOUN
admet-3065	55	12	[	[	X
admet-3065	55	13	6	6	NUM
admet-3065	55	14	]	]	PUNCT
admet-3065	55	15	extracellular	extracellular	ADJ
admet-3065	55	16	barriers	barrier	NOUN
admet-3065	55	17	also	also	ADV
admet-3065	55	18	significantly	significantly	ADV
admet-3065	55	19	contribute	contribute	VERB
admet-3065	55	20	to	to	ADP
admet-3065	55	21	in	in	ADP
admet-3065	55	22	vivo	vivo	ADJ
admet-3065	55	23	gene	gene	NOUN
admet-3065	55	24	delivery	delivery	NOUN
admet-3065	56	1	[	[	X
admet-3065	56	2	30	30	NUM
admet-3065	56	3	]	]	PUNCT
admet-3065	56	4	.	.	PUNCT
admet-3065	57	1	one	one	NUM
admet-3065	57	2	of	of	ADP
admet-3065	57	3	the	the	DET
admet-3065	57	4	largest	large	ADJ
admet-3065	57	5	challenges	challenge	NOUN
admet-3065	57	6	is	be	AUX
admet-3065	57	7	the	the	DET
admet-3065	57	8	stability	stability	NOUN
admet-3065	57	9	of	of	ADP
admet-3065	57	10	the	the	DET
admet-3065	57	11	vector	vector	NOUN
admet-3065	57	12	in	in	ADP
admet-3065	57	13	blood	blood	NOUN
admet-3065	57	14	,	,	PUNCT
admet-3065	57	15	which	which	PRON
admet-3065	57	16	contains	contain	VERB
admet-3065	57	17	a	a	DET
admet-3065	57	18	variety	variety	NOUN
admet-3065	57	19	of	of	ADP
admet-3065	57	20	negatively	negatively	ADV
admet-3065	57	21	charged	charge	VERB
admet-3065	57	22	serum	serum	NOUN
admet-3065	57	23	proteins	protein	NOUN
admet-3065	57	24	and	and	CCONJ
admet-3065	57	25	nucleases	nuclease	NOUN
admet-3065	57	26	that	that	PRON
admet-3065	57	27	can	can	AUX
admet-3065	57	28	degrade	degrade	VERB
admet-3065	57	29	nucleic	nucleic	ADJ
admet-3065	57	30	acids	acid	NOUN
admet-3065	57	31	[	[	X
admet-3065	57	32	37	37	NUM
admet-3065	57	33	]	]	PUNCT
admet-3065	57	34	.	.	PUNCT
admet-3065	58	1	to	to	PART
admet-3065	58	2	avoid	avoid	VERB
admet-3065	58	3	this	this	PRON
admet-3065	58	4	,	,	PUNCT
admet-3065	58	5	gene	gene	NOUN
admet-3065	58	6	delivery	delivery	NOUN
admet-3065	58	7	vectors	vector	NOUN
admet-3065	58	8	are	be	AUX
admet-3065	58	9	often	often	ADV
admet-3065	58	10	designed	design	VERB
admet-3065	58	11	to	to	PART
admet-3065	58	12	shield	shield	VERB
admet-3065	58	13	nucleic	nucleic	ADJ
admet-3065	58	14	acids	acid	NOUN
admet-3065	58	15	,	,	PUNCT
admet-3065	58	16	either	either	CCONJ
admet-3065	58	17	by	by	ADP
admet-3065	58	18	encapsulation	encapsulation	NOUN
admet-3065	58	19	or	or	CCONJ
admet-3065	58	20	by	by	ADP
admet-3065	58	21	modification	modification	NOUN
admet-3065	58	22	of	of	ADP
admet-3065	58	23	surface	surface	NOUN
admet-3065	58	24	epitopes	epitope	NOUN
admet-3065	58	25	,	,	PUNCT
admet-3065	58	26	for	for	ADP
admet-3065	58	27	instance	instance	NOUN
admet-3065	58	28	,	,	PUNCT
admet-3065	58	29	viral	viral	ADJ
admet-3065	58	30	capsid	capsid	NOUN
admet-3065	58	31	proteins	protein	NOUN
admet-3065	58	32	,	,	PUNCT
admet-3065	58	33	to	to	PART
admet-3065	58	34	reduce	reduce	VERB
admet-3065	58	35	immune	immune	ADJ
admet-3065	58	36	recognition	recognition	NOUN
admet-3065	59	1	[	[	X
admet-3065	59	2	27	27	NUM
admet-3065	59	3	]	]	PUNCT
admet-3065	59	4	.	.	PUNCT
admet-3065	60	1	pharmacokinetic	pharmacokinetic	ADJ
admet-3065	60	2	properties	property	NOUN
admet-3065	60	3	like	like	ADP
admet-3065	60	4	circulation	circulation	NOUN
admet-3065	60	5	half	half	ADJ
admet-3065	60	6	-	-	PUNCT
admet-3065	60	7	life	life	NOUN
admet-3065	60	8	and	and	CCONJ
admet-3065	60	9	systemic	systemic	ADJ
admet-3065	60	10	stability	stability	NOUN
admet-3065	60	11	play	play	VERB
admet-3065	60	12	significant	significant	ADJ
admet-3065	60	13	roles	role	NOUN
admet-3065	60	14	in	in	ADP
admet-3065	60	15	vector	vector	NOUN
admet-3065	60	16	design	design	NOUN
admet-3065	60	17	[	[	X
admet-3065	60	18	6	6	NUM
admet-3065	60	19	]	]	PUNCT
admet-3065	60	20	.	.	PUNCT
admet-3065	61	1	the	the	DET
admet-3065	61	2	extracellular	extracellular	ADJ
admet-3065	61	3	matrix	matrix	NOUN
admet-3065	61	4	acts	act	VERB
admet-3065	61	5	as	as	ADP
admet-3065	61	6	a	a	DET
admet-3065	61	7	physical	physical	ADJ
admet-3065	61	8	barrier	barrier	NOUN
admet-3065	61	9	,	,	PUNCT
admet-3065	61	10	and	and	CCONJ
admet-3065	61	11	immune	immune	ADJ
admet-3065	61	12	cells	cell	NOUN
admet-3065	61	13	like	like	ADP
admet-3065	61	14	liver	liver	NOUN
admet-3065	61	15	kupffer	kupffer	NOUN
admet-3065	61	16	cells	cell	NOUN
admet-3065	61	17	and	and	CCONJ
admet-3065	61	18	splenic	splenic	ADJ
admet-3065	61	19	macrophages	macrophage	NOUN
admet-3065	61	20	actively	actively	ADV
admet-3065	61	21	remove	remove	VERB
admet-3065	61	22	extracellular	extracellular	ADJ
admet-3065	61	23	dna	dna	NOUN
admet-3065	61	24	-	-	PUNCT
admet-3065	61	25	containing	contain	VERB
admet-3065	61	26	particles	particle	NOUN
admet-3065	61	27	from	from	ADP
admet-3065	61	28	the	the	DET
admet-3065	61	29	circulation	circulation	NOUN
admet-3065	61	30	[	[	X
admet-3065	61	31	6	6	NUM
admet-3065	61	32	]	]	PUNCT
admet-3065	61	33	.	.	PUNCT
admet-3065	62	1	endosomal	endosomal	ADJ
admet-3065	62	2	entrapment	entrapment	NOUN
admet-3065	62	3	is	be	AUX
admet-3065	62	4	the	the	DET
admet-3065	62	5	major	major	ADJ
admet-3065	62	6	intracellular	intracellular	ADJ
admet-3065	62	7	barrier	barrier	NOUN
admet-3065	62	8	,	,	PUNCT
admet-3065	62	9	where	where	SCONJ
admet-3065	62	10	dna	dna	PROPN
admet-3065	62	11	degradation	degradation	NOUN
admet-3065	62	12	may	may	AUX
admet-3065	62	13	occur	occur	VERB
admet-3065	62	14	before	before	ADP
admet-3065	62	15	reaching	reach	VERB
admet-3065	62	16	the	the	DET
admet-3065	62	17	nucleus	nucleus	NOUN
admet-3065	62	18	[	[	X
admet-3065	62	19	38	38	NUM
admet-3065	62	20	]	]	PUNCT
admet-3065	62	21	.	.	PUNCT
admet-3065	63	1	endosomal	endosomal	ADJ
admet-3065	63	2	escape	escape	NOUN
admet-3065	63	3	mechanisms	mechanism	NOUN
admet-3065	63	4	include	include	VERB
admet-3065	63	5	membrane	membrane	NOUN
admet-3065	63	6	fusion	fusion	NOUN
admet-3065	63	7	,	,	PUNCT
admet-3065	63	8	proton	proton	NOUN
admet-3065	63	9	-	-	PUNCT
admet-3065	63	10	sponge	sponge	NOUN
admet-3065	63	11	effect	effect	NOUN
admet-3065	63	12	,	,	PUNCT
admet-3065	63	13	and	and	CCONJ
admet-3065	63	14	the	the	DET
admet-3065	63	15	use	use	NOUN
admet-3065	63	16	of	of	ADP
admet-3065	63	17	pore	pore	ADJ
admet-3065	63	18	-	-	PUNCT
admet-3065	63	19	forming	form	VERB
admet-3065	63	20	peptides	peptide	NOUN
admet-3065	63	21	[	[	X
admet-3065	63	22	39	39	NUM
admet-3065	63	23	]	]	PUNCT
admet-3065	63	24	.	.	PUNCT
admet-3065	64	1	lipoplexes	lipoplexe	NOUN
admet-3065	64	2	,	,	PUNCT
admet-3065	64	3	for	for	ADP
admet-3065	64	4	instance	instance	NOUN
admet-3065	64	5	,	,	PUNCT
admet-3065	64	6	have	have	AUX
admet-3065	64	7	been	be	AUX
admet-3065	64	8	shown	show	VERB
admet-3065	64	9	to	to	PART
admet-3065	64	10	fuse	fuse	VERB
admet-3065	64	11	with	with	ADP
admet-3065	64	12	endosomal	endosomal	ADJ
admet-3065	64	13	membranes	membrane	NOUN
admet-3065	64	14	,	,	PUNCT
admet-3065	64	15	and	and	CCONJ
admet-3065	64	16	cationic	cationic	ADJ
admet-3065	64	17	polymers	polymer	NOUN
admet-3065	64	18	such	such	ADJ
admet-3065	64	19	as	as	ADP
admet-3065	64	20	pei	pei	PROPN
admet-3065	64	21	and	and	CCONJ
admet-3065	64	22	fusogenic	fusogenic	ADJ
admet-3065	64	23	lipids	lipid	NOUN
admet-3065	64	24	such	such	ADJ
admet-3065	64	25	as	as	ADP
admet-3065	64	26	cholesterol	cholesterol	NOUN
admet-3065	64	27	and	and	CCONJ
admet-3065	64	28	dope	dope	NOUN
admet-3065	64	29	facilitate	facilitate	NOUN
admet-3065	64	30	endosomal	endosomal	ADJ
admet-3065	64	31	release	release	NOUN
admet-3065	64	32	[	[	X
admet-3065	64	33	7	7	NUM
admet-3065	64	34	]	]	PUNCT
admet-3065	64	35	.	.	PUNCT
admet-3065	65	1	once	once	ADV
admet-3065	65	2	internalized	internalize	VERB
admet-3065	65	3	,	,	PUNCT
admet-3065	65	4	the	the	DET
admet-3065	65	5	vector	vector	NOUN
admet-3065	65	6	must	must	AUX
admet-3065	65	7	successfully	successfully	ADV
admet-3065	65	8	navigate	navigate	VERB
admet-3065	65	9	the	the	DET
admet-3065	65	10	cytoplasm	cytoplasm	NOUN
admet-3065	65	11	and	and	CCONJ
admet-3065	65	12	deliver	deliver	VERB
admet-3065	65	13	its	its	PRON
admet-3065	65	14	cargo	cargo	NOUN
admet-3065	65	15	from	from	ADP
admet-3065	65	16	the	the	DET
admet-3065	65	17	endosome	endosome	NOUN
admet-3065	65	18	in	in	ADP
admet-3065	65	19	sufficient	sufficient	ADJ
admet-3065	65	20	time	time	NOUN
admet-3065	65	21	to	to	PART
admet-3065	65	22	facilitate	facilitate	VERB
admet-3065	65	23	nucleus	nucleus	ADJ
admet-3065	65	24	import	import	NOUN
admet-3065	65	25	[	[	X
admet-3065	65	26	36	36	NUM
admet-3065	65	27	]	]	PUNCT
admet-3065	65	28	.	.	PUNCT
admet-3065	66	1	delivery	delivery	NOUN
admet-3065	66	2	of	of	ADP
admet-3065	66	3	genetic	genetic	ADJ
admet-3065	66	4	material	material	NOUN
admet-3065	66	5	into	into	ADP
admet-3065	66	6	the	the	DET
admet-3065	66	7	nucleus	nucleus	NOUN
admet-3065	66	8	is	be	AUX
admet-3065	66	9	of	of	ADP
admet-3065	66	10	primary	primary	ADJ
admet-3065	66	11	importance	importance	NOUN
admet-3065	66	12	to	to	ADP
admet-3065	66	13	therapeutic	therapeutic	ADJ
admet-3065	66	14	effectiveness	effectiveness	NOUN
admet-3065	66	15	[	[	X
admet-3065	66	16	36	36	NUM
admet-3065	66	17	]	]	PUNCT
admet-3065	66	18	.	.	PUNCT
admet-3065	67	1	mechanism	mechanism	NOUN
admet-3065	67	2	of	of	ADP
admet-3065	67	3	liposome	liposome	NOUN
admet-3065	67	4	gene	gene	NOUN
admet-3065	67	5	delivery	delivery	NOUN
admet-3065	67	6	liposomes	liposome	NOUN
admet-3065	67	7	are	be	AUX
admet-3065	67	8	first	first	ADV
admet-3065	67	9	administered	administer	VERB
admet-3065	67	10	as	as	ADP
admet-3065	67	11	vectors	vector	NOUN
admet-3065	67	12	in	in	ADP
admet-3065	67	13	biological	biological	ADJ
admet-3065	67	14	models	model	NOUN
admet-3065	67	15	,	,	PUNCT
admet-3065	67	16	such	such	ADJ
admet-3065	67	17	as	as	ADP
admet-3065	67	18	animals	animal	NOUN
admet-3065	67	19	,	,	PUNCT
admet-3065	67	20	humans	human	NOUN
admet-3065	67	21	,	,	PUNCT
admet-3065	67	22	or	or	CCONJ
admet-3065	67	23	other	other	ADJ
admet-3065	67	24	systems	system	NOUN
admet-3065	67	25	[	[	X
admet-3065	67	26	30	30	NUM
admet-3065	67	27	]	]	PUNCT
admet-3065	67	28	.	.	PUNCT
admet-3065	68	1	the	the	DET
admet-3065	68	2	goal	goal	NOUN
admet-3065	68	3	of	of	ADP
admet-3065	68	4	administration	administration	PROPN
admet-3065	68	5	route	route	NOUN
admet-3065	68	6	selection	selection	NOUN
admet-3065	68	7	(	(	PUNCT
admet-3065	68	8	e.g.	e.g.	ADV
admet-3065	68	9	intravenous	intravenous	ADJ
admet-3065	68	10	,	,	PUNCT
admet-3065	68	11	intramuscular	intramuscular	ADJ
admet-3065	68	12	,	,	PUNCT
admet-3065	68	13	or	or	CCONJ
admet-3065	68	14	intratracheal	intratracheal	NOUN
admet-3065	68	15	)	)	PUNCT
admet-3065	68	16	is	be	AUX
admet-3065	68	17	to	to	PART
admet-3065	68	18	deliver	deliver	VERB
admet-3065	68	19	the	the	DET
admet-3065	68	20	vector	vector	NOUN
admet-3065	68	21	optimally	optimally	ADV
admet-3065	68	22	to	to	ADP
admet-3065	68	23	target	target	VERB
admet-3065	68	24	cells	cell	NOUN
admet-3065	68	25	,	,	PUNCT
admet-3065	68	26	which	which	PRON
admet-3065	68	27	may	may	AUX
admet-3065	68	28	be	be	AUX
admet-3065	68	29	located	locate	VERB
admet-3065	68	30	in	in	ADP
admet-3065	68	31	specific	specific	ADJ
admet-3065	68	32	tissues	tissue	NOUN
admet-3065	68	33	or	or	CCONJ
admet-3065	68	34	blood	blood	NOUN
admet-3065	68	35	vessels	vessel	NOUN
admet-3065	68	36	[	[	X
admet-3065	68	37	6	6	NUM
admet-3065	68	38	]	]	PUNCT
admet-3065	68	39	.	.	PUNCT
admet-3065	69	1	in	in	ADP
admet-3065	69	2	the	the	DET
admet-3065	69	3	case	case	NOUN
admet-3065	69	4	of	of	ADP
admet-3065	69	5	vascular	vascular	ADJ
admet-3065	69	6	administration	administration	NOUN
admet-3065	69	7	,	,	PUNCT
admet-3065	69	8	the	the	DET
admet-3065	69	9	vectors	vector	NOUN
admet-3065	69	10	must	must	AUX
admet-3065	69	11	contend	contend	VERB
admet-3065	69	12	with	with	ADP
admet-3065	69	13	serum	serum	NOUN
admet-3065	69	14	proteins	protein	NOUN
admet-3065	69	15	and	and	CCONJ
admet-3065	69	16	blood	blood	NOUN
admet-3065	69	17	components	component	NOUN
admet-3065	69	18	[	[	X
admet-3065	69	19	37	37	NUM
admet-3065	69	20	]	]	PUNCT
admet-3065	69	21	.	.	PUNCT
admet-3065	70	1	subsequently	subsequently	ADV
admet-3065	70	2	,	,	PUNCT
admet-3065	70	3	liposomes	liposome	NOUN
admet-3065	70	4	extravasate	extravasate	VERB
admet-3065	70	5	from	from	ADP
admet-3065	70	6	blood	blood	NOUN
admet-3065	70	7	vessels	vessel	NOUN
admet-3065	70	8	into	into	ADP
admet-3065	70	9	target	target	NOUN
admet-3065	70	10	tissues	tissue	NOUN
admet-3065	70	11	via	via	ADP
admet-3065	70	12	active	active	ADJ
admet-3065	70	13	or	or	CCONJ
admet-3065	70	14	passive	passive	ADJ
admet-3065	70	15	targeting	targeting	NOUN
admet-3065	70	16	[	[	X
admet-3065	70	17	2	2	NUM
admet-3065	70	18	]	]	PUNCT
admet-3065	70	19	.	.	PUNCT
admet-3065	71	1	following	follow	VERB
admet-3065	71	2	extravasation	extravasation	NOUN
admet-3065	71	3	,	,	PUNCT
admet-3065	71	4	they	they	PRON
admet-3065	71	5	bind	bind	VERB
admet-3065	71	6	to	to	ADP
admet-3065	71	7	specific	specific	ADJ
admet-3065	71	8	cell	cell	NOUN
admet-3065	71	9	surface	surface	NOUN
admet-3065	71	10	receptors	receptor	NOUN
admet-3065	71	11	that	that	PRON
admet-3065	71	12	stimulate	stimulate	VERB
admet-3065	71	13	endocytosis	endocytosis	NOUN
admet-3065	71	14	[	[	X
admet-3065	71	15	31,38	31,38	NOUN
admet-3065	71	16	]	]	X
admet-3065	71	17	(	(	PUNCT
admet-3065	71	18	figure	figure	NOUN
admet-3065	71	19	1	1	NUM
admet-3065	71	20	)	)	PUNCT
admet-3065	71	21	.	.	PUNCT
admet-3065	72	1	during	during	ADP
admet-3065	72	2	cellular	cellular	ADJ
admet-3065	72	3	uptake	uptake	NOUN
admet-3065	72	4	,	,	PUNCT
admet-3065	72	5	the	the	DET
admet-3065	72	6	endosomal	endosomal	ADJ
admet-3065	72	7	vesicles	vesicle	NOUN
admet-3065	72	8	containing	contain	VERB
admet-3065	72	9	the	the	DET
admet-3065	72	10	liposomal	liposomal	ADJ
admet-3065	72	11	vectors	vector	NOUN
admet-3065	72	12	undergo	undergo	VERB
admet-3065	72	13	acidification	acidification	NOUN
admet-3065	72	14	as	as	SCONJ
admet-3065	72	15	lysosomes	lysosome	NOUN
admet-3065	72	16	begin	begin	VERB
admet-3065	72	17	to	to	PART
admet-3065	72	18	merge	merge	VERB
admet-3065	72	19	with	with	ADP
admet-3065	72	20	them	they	PRON
admet-3065	72	21	[	[	X
admet-3065	72	22	35	35	NUM
admet-3065	72	23	]	]	PUNCT
admet-3065	72	24	.	.	PUNCT
admet-3065	73	1	as	as	SCONJ
admet-3065	73	2	the	the	DET
admet-3065	73	3	vesicle	vesicle	NOUN
admet-3065	73	4	ph	ph	NOUN
admet-3065	73	5	decreases	decrease	NOUN
admet-3065	73	6	,	,	PUNCT
admet-3065	73	7	amine	amine	ADJ
admet-3065	73	8	groups	group	NOUN
admet-3065	73	9	on	on	ADP
admet-3065	73	10	the	the	DET
admet-3065	73	11	liposomes	liposome	NOUN
admet-3065	73	12	absorb	absorb	VERB
admet-3065	73	13	h⁺	h⁺	PROPN
admet-3065	73	14	ions	ion	NOUN
admet-3065	73	15	[	[	X
admet-3065	73	16	39	39	NUM
admet-3065	73	17	]	]	PUNCT
admet-3065	73	18	.	.	PUNCT
admet-3065	74	1	to	to	PART
admet-3065	74	2	maintain	maintain	VERB
admet-3065	74	3	ionic	ionic	ADJ
admet-3065	74	4	balance	balance	NOUN
admet-3065	74	5	,	,	PUNCT
admet-3065	74	6	the	the	DET
admet-3065	74	7	vesicle	vesicle	NOUN
admet-3065	74	8	then	then	ADV
admet-3065	74	9	takes	take	VERB
admet-3065	74	10	up	up	ADP
admet-3065	74	11	cl⁻	cl⁻	NOUN
admet-3065	74	12	ions	ion	NOUN
admet-3065	74	13	,	,	PUNCT
admet-3065	74	14	which	which	PRON
admet-3065	74	15	enter	enter	AUX
admet-3065	74	16	accompanied	accompany	VERB
admet-3065	74	17	by	by	ADP
admet-3065	74	18	water	water	NOUN
admet-3065	74	19	molecules	molecule	NOUN
admet-3065	74	20	,	,	PUNCT
admet-3065	74	21	ultimately	ultimately	ADV
admet-3065	74	22	causing	cause	VERB
admet-3065	74	23	the	the	DET
admet-3065	74	24	vesicle	vesicle	NOUN
admet-3065	74	25	to	to	PART
admet-3065	74	26	burst	burst	VERB
admet-3065	74	27	a	a	DET
admet-3065	74	28	phenomenon	phenomenon	NOUN
admet-3065	74	29	known	know	VERB
admet-3065	74	30	as	as	ADP
admet-3065	74	31	the	the	DET
admet-3065	74	32	proton	proton	NOUN
admet-3065	74	33	sponge	sponge	NOUN
admet-3065	74	34	effect	effect	NOUN
admet-3065	74	35	[	[	X
admet-3065	74	36	40	40	NUM
admet-3065	74	37	]	]	PUNCT
admet-3065	74	38	.	.	PUNCT
admet-3065	75	1	e.	e.	PROPN
admet-3065	75	2	j.	j.	PROPN
admet-3065	75	3	saleh	saleh	PROPN
admet-3065	75	4	et	et	PROPN
admet-3065	75	5	al	al	PROPN
admet-3065	75	6	.	.	PROPN
admet-3065	75	7	admet	admet	PROPN
admet-3065	75	8	&	&	CCONJ
admet-3065	75	9	dmpk	dmpk	PROPN
admet-3065	75	10	00(0	00(0	PROPN
admet-3065	75	11	)	)	PUNCT
admet-3065	75	12	(	(	PUNCT
admet-3065	75	13	2025	2025	NUM
admet-3065	75	14	)	)	PUNCT
admet-3065	75	15	3065	3065	NUM
admet-3065	75	16	4	4	NUM
admet-3065	75	17	alternatively	alternatively	ADV
admet-3065	75	18	,	,	PUNCT
admet-3065	75	19	fusogenic	fusogenic	ADJ
admet-3065	75	20	lipids	lipid	NOUN
admet-3065	75	21	represent	represent	VERB
admet-3065	75	22	another	another	DET
admet-3065	75	23	important	important	ADJ
admet-3065	75	24	escape	escape	NOUN
admet-3065	75	25	mechanism	mechanism	NOUN
admet-3065	75	26	;	;	PUNCT
admet-3065	75	27	as	as	SCONJ
admet-3065	75	28	the	the	DET
admet-3065	75	29	vesicle	vesicle	NOUN
admet-3065	75	30	ph	ph	NOUN
admet-3065	75	31	continues	continue	VERB
admet-3065	75	32	to	to	PART
admet-3065	75	33	drop	drop	VERB
admet-3065	75	34	,	,	PUNCT
admet-3065	75	35	these	these	DET
admet-3065	75	36	lipids	lipid	NOUN
admet-3065	75	37	become	become	VERB
admet-3065	75	38	activated	activate	VERB
admet-3065	75	39	,	,	PUNCT
admet-3065	75	40	facilitating	facilitate	VERB
admet-3065	75	41	cargo	cargo	NOUN
admet-3065	75	42	release	release	NOUN
admet-3065	75	43	into	into	ADP
admet-3065	75	44	the	the	DET
admet-3065	75	45	cytoplasm	cytoplasm	NOUN
admet-3065	75	46	[	[	X
admet-3065	75	47	7	7	NUM
admet-3065	75	48	]	]	PUNCT
admet-3065	75	49	.	.	PUNCT
admet-3065	76	1	in	in	ADP
admet-3065	76	2	some	some	DET
admet-3065	76	3	cases	case	NOUN
admet-3065	76	4	,	,	PUNCT
admet-3065	76	5	cellpenetrating	cellpenetrate	VERB
admet-3065	76	6	peptides	peptide	NOUN
admet-3065	76	7	bind	bind	VERB
admet-3065	76	8	to	to	ADP
admet-3065	76	9	liposomes	liposome	NOUN
admet-3065	76	10	and	and	CCONJ
admet-3065	76	11	,	,	PUNCT
admet-3065	76	12	upon	upon	SCONJ
admet-3065	76	13	ph	ph	ADJ
admet-3065	76	14	reduction	reduction	NOUN
admet-3065	76	15	,	,	PUNCT
admet-3065	76	16	form	form	NOUN
admet-3065	76	17	pores	pore	NOUN
admet-3065	76	18	in	in	ADP
admet-3065	76	19	the	the	DET
admet-3065	76	20	vesicle	vesicle	NOUN
admet-3065	76	21	membrane	membrane	NOUN
admet-3065	76	22	[	[	X
admet-3065	76	23	41	41	NUM
admet-3065	76	24	]	]	PUNCT
admet-3065	76	25	.	.	PUNCT
admet-3065	77	1	however	however	ADV
admet-3065	77	2	,	,	PUNCT
admet-3065	77	3	in	in	ADP
admet-3065	77	4	most	most	ADJ
admet-3065	77	5	instances	instance	NOUN
admet-3065	77	6	,	,	PUNCT
admet-3065	77	7	if	if	SCONJ
admet-3065	77	8	escape	escape	NOUN
admet-3065	77	9	mechanisms	mechanism	NOUN
admet-3065	77	10	fail	fail	VERB
admet-3065	77	11	,	,	PUNCT
admet-3065	77	12	lysosomes	lysosome	NOUN
admet-3065	77	13	fully	fully	ADV
admet-3065	77	14	merge	merge	VERB
admet-3065	77	15	with	with	ADP
admet-3065	77	16	the	the	DET
admet-3065	77	17	vesicle	vesicle	NOUN
admet-3065	77	18	,	,	PUNCT
admet-3065	77	19	activating	activate	VERB
admet-3065	77	20	ph	ph	ADJ
admet-3065	77	21	sensitive	sensitive	ADJ
admet-3065	77	22	enzymes	enzyme	NOUN
admet-3065	77	23	that	that	PRON
admet-3065	77	24	degrade	degrade	VERB
admet-3065	77	25	the	the	DET
admet-3065	77	26	cargo	cargo	NOUN
admet-3065	77	27	[	[	X
admet-3065	77	28	35	35	NUM
admet-3065	77	29	]	]	PUNCT
admet-3065	77	30	.	.	PUNCT
admet-3065	78	1	figure	figure	NOUN
admet-3065	78	2	1	1	NUM
admet-3065	78	3	.	.	PUNCT
admet-3065	79	1	the	the	DET
admet-3065	79	2	schematic	schematic	ADJ
admet-3065	79	3	of	of	ADP
admet-3065	79	4	key	key	ADJ
admet-3065	79	5	steps	step	NOUN
admet-3065	79	6	in	in	ADP
admet-3065	79	7	liposome	liposome	NOUN
admet-3065	79	8	-	-	PUNCT
admet-3065	79	9	mediated	mediate	VERB
admet-3065	79	10	gene	gene	NOUN
admet-3065	79	11	therapy	therapy	NOUN
admet-3065	79	12	.	.	PUNCT
admet-3065	80	1	1	1	NUM
admet-3065	80	2	the	the	DET
admet-3065	80	3	process	process	NOUN
admet-3065	80	4	begins	begin	VERB
admet-3065	80	5	with	with	ADP
admet-3065	80	6	the	the	DET
admet-3065	80	7	administration	administration	NOUN
admet-3065	80	8	of	of	ADP
admet-3065	80	9	liposomes	liposome	NOUN
admet-3065	80	10	into	into	ADP
admet-3065	80	11	the	the	DET
admet-3065	80	12	bloodstream	bloodstream	NOUN
admet-3065	80	13	.	.	PUNCT
admet-3065	81	1	2	2	NUM
admet-3065	81	2	the	the	DET
admet-3065	81	3	liposomes	liposome	NOUN
admet-3065	81	4	then	then	ADV
admet-3065	81	5	extravasate	extravasate	VERB
admet-3065	81	6	from	from	ADP
admet-3065	81	7	the	the	DET
admet-3065	81	8	blood	blood	NOUN
admet-3065	81	9	vessels	vessel	NOUN
admet-3065	81	10	into	into	ADP
admet-3065	81	11	the	the	DET
admet-3065	81	12	target	target	NOUN
admet-3065	81	13	tissue	tissue	NOUN
admet-3065	81	14	,	,	PUNCT
admet-3065	81	15	3	3	NUM
admet-3065	81	16	bind	bind	VERB
admet-3065	81	17	to	to	ADP
admet-3065	81	18	specific	specific	ADJ
admet-3065	81	19	receptors	receptor	NOUN
admet-3065	81	20	,	,	PUNCT
admet-3065	81	21	and	and	CCONJ
admet-3065	81	22	are	be	AUX
admet-3065	81	23	4	4	NUM
admet-3065	81	24	internalized	internalize	VERB
admet-3065	81	25	via	via	ADP
admet-3065	81	26	endocytosis	endocytosis	NOUN
admet-3065	81	27	.	.	PUNCT
admet-3065	82	1	5	5	NUM
admet-3065	82	2	,	,	PUNCT
admet-3065	82	3	6	6	NUM
admet-3065	82	4	subsequent	subsequent	ADJ
admet-3065	82	5	endosomal	endosomal	ADJ
admet-3065	82	6	escape	escape	NOUN
admet-3065	82	7	,	,	PUNCT
admet-3065	82	8	mediated	mediate	VERB
admet-3065	82	9	by	by	ADP
admet-3065	82	10	mechanisms	mechanism	NOUN
admet-3065	82	11	such	such	ADJ
admet-3065	82	12	as	as	ADP
admet-3065	82	13	the	the	DET
admet-3065	82	14	sponge	sponge	NOUN
admet-3065	82	15	effect	effect	NOUN
admet-3065	82	16	,	,	PUNCT
admet-3065	82	17	fusogenic	fusogenic	ADJ
admet-3065	82	18	lipids	lipid	NOUN
admet-3065	82	19	,	,	PUNCT
admet-3065	82	20	or	or	CCONJ
admet-3065	82	21	penetration	penetration	NOUN
admet-3065	82	22	peptides	peptide	NOUN
admet-3065	82	23	,	,	PUNCT
admet-3065	82	24	protects	protect	VERB
admet-3065	82	25	the	the	DET
admet-3065	82	26	cargo	cargo	NOUN
admet-3065	82	27	from	from	ADP
admet-3065	82	28	lysosomal	lysosomal	ADJ
admet-3065	82	29	degradation	degradation	NOUN
admet-3065	82	30	and	and	CCONJ
admet-3065	82	31	enables	enable	VERB
admet-3065	82	32	its	its	PRON
admet-3065	82	33	release	release	NOUN
admet-3065	82	34	.	.	PUNCT
admet-3065	83	1	7	7	NUM
admet-3065	83	2	,	,	PUNCT
admet-3065	83	3	8.1	8.1	NUM
admet-3065	83	4	the	the	DET
admet-3065	83	5	cargo	cargo	NOUN
admet-3065	83	6	can	can	AUX
admet-3065	83	7	then	then	ADV
admet-3065	83	8	either	either	CCONJ
admet-3065	83	9	enter	enter	VERB
admet-3065	83	10	the	the	DET
admet-3065	83	11	nucleus	nucleus	NOUN
admet-3065	83	12	or	or	CCONJ
admet-3065	83	13	8.2	8.2	NUM
admet-3065	83	14	perform	perform	VERB
admet-3065	83	15	its	its	PRON
admet-3065	83	16	function	function	NOUN
admet-3065	83	17	in	in	ADP
admet-3065	83	18	the	the	DET
admet-3065	83	19	cytoplasm	cytoplasm	NOUN
admet-3065	83	20	.	.	PUNCT
admet-3065	84	1	the	the	DET
admet-3065	84	2	figure	figure	NOUN
admet-3065	84	3	was	be	AUX
admet-3065	84	4	created	create	VERB
admet-3065	84	5	with	with	ADP
admet-3065	84	6	biorender.com	biorender.com	X
admet-3065	84	7	[	[	X
admet-3065	84	8	42	42	NUM
admet-3065	84	9	]	]	PUNCT
admet-3065	84	10	liposome	liposome	NOUN
admet-3065	84	11	composition	composition	NOUN
admet-3065	84	12	and	and	CCONJ
admet-3065	84	13	structure	structure	NOUN
admet-3065	84	14	it	it	PRON
admet-3065	84	15	has	have	AUX
admet-3065	84	16	been	be	AUX
admet-3065	84	17	well	well	ADV
admet-3065	84	18	known	know	VERB
admet-3065	84	19	that	that	SCONJ
admet-3065	84	20	liposome	liposome	NOUN
admet-3065	84	21	characteristics	characteristic	NOUN
admet-3065	84	22	are	be	AUX
admet-3065	84	23	highly	highly	ADV
admet-3065	84	24	dependent	dependent	ADJ
admet-3065	84	25	on	on	ADP
admet-3065	84	26	lipid	lipid	ADJ
admet-3065	84	27	composition	composition	NOUN
admet-3065	84	28	and	and	CCONJ
admet-3065	84	29	structure	structure	NOUN
admet-3065	84	30	,	,	PUNCT
admet-3065	84	31	which	which	PRON
admet-3065	84	32	include	include	VERB
admet-3065	84	33	head	head	NOUN
admet-3065	84	34	,	,	PUNCT
admet-3065	84	35	tail	tail	NOUN
admet-3065	84	36	,	,	PUNCT
admet-3065	84	37	and	and	CCONJ
admet-3065	84	38	body	body	NOUN
admet-3065	84	39	[	[	X
admet-3065	84	40	43	43	NUM
admet-3065	84	41	]	]	PUNCT
admet-3065	84	42	.	.	PUNCT
admet-3065	85	1	also	also	ADV
admet-3065	85	2	,	,	PUNCT
admet-3065	85	3	all	all	DET
admet-3065	85	4	parts	part	NOUN
admet-3065	85	5	of	of	ADP
admet-3065	85	6	lipids	lipid	NOUN
admet-3065	85	7	have	have	VERB
admet-3065	85	8	special	special	ADJ
admet-3065	85	9	roles	role	NOUN
admet-3065	85	10	that	that	PRON
admet-3065	85	11	will	will	AUX
admet-3065	85	12	be	be	AUX
admet-3065	85	13	discussed	discuss	VERB
admet-3065	85	14	in	in	ADP
admet-3065	85	15	continuation	continuation	NOUN
admet-3065	85	16	[	[	X
admet-3065	85	17	44	44	NUM
admet-3065	85	18	]	]	PUNCT
admet-3065	85	19	.	.	PUNCT
admet-3065	86	1	the	the	DET
admet-3065	86	2	head	head	NOUN
admet-3065	86	3	group	group	NOUN
admet-3065	86	4	of	of	ADP
admet-3065	86	5	phospholipids	phospholipid	NOUN
admet-3065	86	6	plays	play	VERB
admet-3065	86	7	a	a	DET
admet-3065	86	8	prominent	prominent	ADJ
admet-3065	86	9	role	role	NOUN
admet-3065	86	10	in	in	ADP
admet-3065	86	11	phospholipid	phospholipid	NOUN
admet-3065	86	12	charge	charge	NOUN
admet-3065	86	13	[	[	X
admet-3065	86	14	45	45	NUM
admet-3065	86	15	]	]	PUNCT
admet-3065	86	16	.	.	PUNCT
admet-3065	87	1	the	the	DET
admet-3065	87	2	lipid	lipid	NOUN
admet-3065	87	3	-	-	PUNCT
admet-3065	87	4	based	base	VERB
admet-3065	87	5	vector	vector	NOUN
admet-3065	87	6	body	body	NOUN
admet-3065	87	7	consists	consist	VERB
admet-3065	87	8	of	of	ADP
admet-3065	87	9	the	the	DET
admet-3065	87	10	connecting	connect	VERB
admet-3065	87	11	tail	tail	NOUN
admet-3065	87	12	and	and	CCONJ
admet-3065	87	13	head	head	NOUN
admet-3065	87	14	group	group	NOUN
admet-3065	87	15	[	[	X
admet-3065	87	16	46	46	NUM
admet-3065	87	17	]	]	PUNCT
admet-3065	87	18	.	.	PUNCT
admet-3065	88	1	tails	tail	NOUN
admet-3065	88	2	are	be	AUX
admet-3065	88	3	essential	essential	ADJ
admet-3065	88	4	for	for	ADP
admet-3065	88	5	the	the	DET
admet-3065	88	6	rigidity	rigidity	NOUN
admet-3065	88	7	and	and	CCONJ
admet-3065	88	8	leak	leak	NOUN
admet-3065	88	9	resistance	resistance	NOUN
admet-3065	88	10	of	of	ADP
admet-3065	88	11	the	the	DET
admet-3065	88	12	vector	vector	NOUN
admet-3065	89	1	[	[	X
admet-3065	89	2	47	47	NUM
admet-3065	89	3	]	]	PUNCT
admet-3065	89	4	.	.	PUNCT
admet-3065	90	1	nanoliposomes	nanoliposome	NOUN
admet-3065	90	2	,	,	PUNCT
admet-3065	90	3	which	which	PRON
admet-3065	90	4	are	be	AUX
admet-3065	90	5	self	self	NOUN
admet-3065	90	6	-	-	PUNCT
admet-3065	90	7	assembled	assemble	VERB
admet-3065	90	8	phospholipid	phospholipid	NOUN
admet-3065	90	9	vesicular	vesicular	ADJ
admet-3065	90	10	structures	structure	NOUN
admet-3065	90	11	,	,	PUNCT
admet-3065	90	12	vary	vary	VERB
admet-3065	90	13	from	from	ADP
admet-3065	90	14	unilamellar	unilamellar	ADJ
admet-3065	90	15	to	to	ADP
admet-3065	90	16	multilamellar	multilamellar	ADJ
admet-3065	90	17	structures	structure	NOUN
admet-3065	90	18	,	,	PUNCT
admet-3065	90	19	varying	vary	VERB
admet-3065	90	20	from	from	ADP
admet-3065	90	21	unilamellar	unilamellar	ADJ
admet-3065	90	22	vesicles	vesicle	NOUN
admet-3065	90	23	(	(	PUNCT
admet-3065	90	24	ulvs	ulvs	NOUN
admet-3065	90	25	)	)	PUNCT
admet-3065	90	26	,	,	PUNCT
admet-3065	90	27	oligolamellar	oligolamellar	ADJ
admet-3065	90	28	vesicles	vesicle	NOUN
admet-3065	90	29	(	(	PUNCT
admet-3065	90	30	olvs	olvs	ADJ
admet-3065	90	31	)	)	PUNCT
admet-3065	90	32	,	,	PUNCT
admet-3065	90	33	multilamellar	multilamellar	ADJ
admet-3065	90	34	vesicles	vesicle	NOUN
admet-3065	90	35	(	(	PUNCT
admet-3065	90	36	mlvs	mlvs	NOUN
admet-3065	90	37	)	)	PUNCT
admet-3065	90	38	,	,	PUNCT
admet-3065	90	39	and	and	CCONJ
admet-3065	90	40	multivesicular	multivesicular	ADJ
admet-3065	90	41	liposomes	liposome	NOUN
admet-3065	90	42	(	(	PUNCT
admet-3065	90	43	mvls)-with	mvls)-with	ADP
admet-3065	90	44	varying	vary	VERB
admet-3065	90	45	effects	effect	NOUN
admet-3065	90	46	on	on	ADP
admet-3065	90	47	gene	gene	NOUN
admet-3065	90	48	delivery	delivery	NOUN
admet-3065	90	49	efficiency	efficiency	NOUN
admet-3065	91	1	[	[	X
admet-3065	91	2	48,49	48,49	X
admet-3065	91	3	]	]	X
admet-3065	91	4	(	(	PUNCT
admet-3065	91	5	figure	figure	NOUN
admet-3065	91	6	2	2	NUM
admet-3065	91	7	)	)	PUNCT
admet-3065	91	8	.	.	PUNCT
admet-3065	92	1	admet	admet	PROPN
admet-3065	92	2	&	&	CCONJ
admet-3065	92	3	dmpk	dmpk	PROPN
admet-3065	92	4	00(0	00(0	PROPN
admet-3065	92	5	)	)	PUNCT
admet-3065	92	6	(	(	PUNCT
admet-3065	92	7	2025	2025	NUM
admet-3065	92	8	)	)	PUNCT
admet-3065	92	9	3065	3065	NUM
admet-3065	92	10	liposome	liposome	NOUN
admet-3065	92	11	-	-	PUNCT
admet-3065	92	12	mediated	mediate	VERB
admet-3065	92	13	gene	gene	NOUN
admet-3065	92	14	delivery	delivery	NOUN
admet-3065	92	15	doi	doi	NOUN
admet-3065	92	16	:	:	PUNCT
admet-3065	92	17	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	92	18	5	5	NUM
admet-3065	92	19	figure	figure	NOUN
admet-3065	92	20	2	2	NUM
admet-3065	92	21	.	.	PUNCT
admet-3065	92	22	classification	classification	NOUN
admet-3065	92	23	of	of	ADP
admet-3065	92	24	liposomal	liposomal	ADJ
admet-3065	92	25	vesicles	vesicle	NOUN
admet-3065	92	26	based	base	VERB
admet-3065	92	27	on	on	ADP
admet-3065	92	28	lamellar	lamellar	ADJ
admet-3065	92	29	structure	structure	NOUN
admet-3065	92	30	and	and	CCONJ
admet-3065	92	31	size	size	NOUN
admet-3065	92	32	.	.	PUNCT
admet-3065	93	1	the	the	DET
admet-3065	93	2	figure	figure	NOUN
admet-3065	93	3	depicts	depict	VERB
admet-3065	93	4	various	various	ADJ
admet-3065	93	5	types	type	NOUN
admet-3065	93	6	of	of	ADP
admet-3065	93	7	liposomal	liposomal	ADJ
admet-3065	93	8	vesicles	vesicle	NOUN
admet-3065	93	9	,	,	PUNCT
admet-3065	93	10	including	include	VERB
admet-3065	93	11	:	:	PUNCT
admet-3065	93	12	olv	olv	X
admet-3065	93	13	(	(	PUNCT
admet-3065	93	14	oligolamellar	oligolamellar	ADJ
admet-3065	93	15	vesicles	vesicle	NOUN
admet-3065	93	16	)	)	PUNCT
admet-3065	93	17	,	,	PUNCT
admet-3065	93	18	luv	luv	PROPN
admet-3065	93	19	(	(	PUNCT
admet-3065	93	20	large	large	ADJ
admet-3065	93	21	unilamellar	unilamellar	ADJ
admet-3065	93	22	vesicles	vesicle	NOUN
admet-3065	93	23	,	,	PUNCT
admet-3065	93	24	100	100	ADJ
admet-3065	93	25	nm	nm	NOUN
admet-3065	93	26	)	)	PUNCT
admet-3065	93	27	,	,	PUNCT
admet-3065	93	28	mlv	mlv	INTJ
admet-3065	93	29	(	(	PUNCT
admet-3065	93	30	multilamellar	multilamellar	ADJ
admet-3065	93	31	vesicles	vesicle	NOUN
admet-3065	93	32	,	,	PUNCT
admet-3065	93	33	1	1	PROPN
admet-3065	93	34	μm	μm	NUM
admet-3065	93	35	)	)	PUNCT
admet-3065	93	36	,	,	PUNCT
admet-3065	93	37	guv	guv	NOUN
admet-3065	93	38	(	(	PUNCT
admet-3065	93	39	giant	giant	ADJ
admet-3065	93	40	unilamellar	unilamellar	ADJ
admet-3065	93	41	vesicles	vesicle	NOUN
admet-3065	93	42	)	)	PUNCT
admet-3065	93	43	.	.	PUNCT
admet-3065	94	1	cationic	cationic	VERB
admet-3065	94	2	lipids	lipids	ADP
admet-3065	94	3	contemporary	contemporary	ADJ
admet-3065	94	4	research	research	NOUN
admet-3065	94	5	classifies	classify	VERB
admet-3065	94	6	cationic	cationic	ADJ
admet-3065	94	7	lipids	lipid	NOUN
admet-3065	94	8	into	into	ADP
admet-3065	94	9	four	four	NUM
admet-3065	94	10	fundamental	fundamental	ADJ
admet-3065	94	11	structural	structural	ADJ
admet-3065	94	12	components	component	NOUN
admet-3065	94	13	that	that	PRON
admet-3065	94	14	govern	govern	VERB
admet-3065	94	15	their	their	PRON
admet-3065	94	16	functionality	functionality	NOUN
admet-3065	94	17	[	[	X
admet-3065	94	18	50	50	NUM
admet-3065	94	19	]	]	PUNCT
admet-3065	94	20	.	.	PUNCT
admet-3065	95	1	the	the	DET
admet-3065	95	2	hydrophobic	hydrophobic	NOUN
admet-3065	95	3	core	core	NOUN
admet-3065	95	4	typically	typically	ADV
admet-3065	95	5	features	feature	VERB
admet-3065	95	6	either	either	CCONJ
admet-3065	95	7	saturated	saturated	ADJ
admet-3065	95	8	alkyl	alkyl	ADJ
admet-3065	95	9	chains	chain	NOUN
admet-3065	95	10	(	(	PUNCT
admet-3065	95	11	c12	c12	NOUN
admet-3065	95	12	-	-	PUNCT
admet-3065	95	13	c20	c20	NOUN
admet-3065	95	14	)	)	PUNCT
admet-3065	95	15	or	or	CCONJ
admet-3065	95	16	cholesterol	cholesterol	NOUN
admet-3065	95	17	derivatives	derivative	NOUN
admet-3065	95	18	[	[	X
admet-3065	95	19	51	51	NUM
admet-3065	95	20	]	]	PUNCT
admet-3065	95	21	,	,	PUNCT
admet-3065	95	22	with	with	ADP
admet-3065	95	23	these	these	DET
admet-3065	95	24	moieties	moiety	NOUN
admet-3065	95	25	predominantly	predominantly	ADV
admet-3065	95	26	linked	link	VERB
admet-3065	95	27	via	via	ADP
admet-3065	95	28	robust	robust	ADJ
admet-3065	95	29	ester	ester	NOUN
admet-3065	95	30	or	or	CCONJ
admet-3065	95	31	ether	ether	NOUN
admet-3065	95	32	bonds	bond	NOUN
admet-3065	95	33	.	.	PUNCT
admet-3065	96	1	serving	serve	VERB
admet-3065	96	2	as	as	ADP
admet-3065	96	3	the	the	DET
admet-3065	96	4	molecular	molecular	ADJ
admet-3065	96	5	scaffold	scaffold	NOUN
admet-3065	96	6	,	,	PUNCT
admet-3065	96	7	the	the	DET
admet-3065	96	8	backbone	backbone	NOUN
admet-3065	96	9	structure	structure	NOUN
admet-3065	96	10	most	most	ADV
admet-3065	96	11	commonly	commonly	ADV
admet-3065	96	12	employs	employ	VERB
admet-3065	96	13	a	a	DET
admet-3065	96	14	glycerol	glycerol	NOUN
admet-3065	96	15	framework	framework	NOUN
admet-3065	96	16	,	,	PUNCT
admet-3065	96	17	although	although	SCONJ
admet-3065	96	18	innovative	innovative	ADJ
admet-3065	96	19	designs	design	NOUN
admet-3065	96	20	have	have	AUX
admet-3065	96	21	incorporated	incorporate	VERB
admet-3065	96	22	amino	amino	NOUN
admet-3065	96	23	acid	acid	NOUN
admet-3065	96	24	residues	residue	NOUN
admet-3065	96	25	and	and	CCONJ
admet-3065	96	26	aromatic	aromatic	ADJ
admet-3065	96	27	systems	system	NOUN
admet-3065	96	28	.	.	PUNCT
admet-3065	97	1	the	the	DET
admet-3065	97	2	cationic	cationic	ADJ
admet-3065	97	3	headgroup	headgroup	NOUN
admet-3065	97	4	domain	domain	NOUN
admet-3065	97	5	,	,	PUNCT
admet-3065	97	6	crucial	crucial	ADJ
admet-3065	97	7	for	for	ADP
admet-3065	97	8	nucleic	nucleic	ADJ
admet-3065	97	9	acid	acid	ADJ
admet-3065	97	10	complexation	complexation	NOUN
admet-3065	97	11	,	,	PUNCT
admet-3065	97	12	predominantly	predominantly	ADV
admet-3065	97	13	utilizes	utilize	VERB
admet-3065	97	14	quaternary	quaternary	ADJ
admet-3065	97	15	ammonium	ammonium	NOUN
admet-3065	97	16	groups	group	NOUN
admet-3065	97	17	that	that	PRON
admet-3065	97	18	have	have	AUX
admet-3065	97	19	demonstrated	demonstrate	VERB
admet-3065	97	20	exceptional	exceptional	ADJ
admet-3065	97	21	delivery	delivery	NOUN
admet-3065	97	22	efficiency	efficiency	NOUN
admet-3065	97	23	.	.	PUNCT
admet-3065	98	1	researchers	researcher	NOUN
admet-3065	98	2	have	have	AUX
admet-3065	98	3	also	also	ADV
admet-3065	98	4	explored	explore	VERB
admet-3065	98	5	diverse	diverse	ADJ
admet-3065	98	6	cationic	cationic	ADJ
admet-3065	98	7	alternatives	alternative	NOUN
admet-3065	98	8	,	,	PUNCT
admet-3065	98	9	including	include	VERB
admet-3065	98	10	polyamine	polyamine	NOUN
admet-3065	98	11	chains	chain	NOUN
admet-3065	98	12	,	,	PUNCT
admet-3065	98	13	guanidinium	guanidinium	NOUN
admet-3065	98	14	units	unit	NOUN
admet-3065	98	15	,	,	PUNCT
admet-3065	98	16	heterocyclic	heterocyclic	ADJ
admet-3065	98	17	systems	system	NOUN
admet-3065	98	18	,	,	PUNCT
admet-3065	98	19	and	and	CCONJ
admet-3065	98	20	biomimetic	biomimetic	ADJ
admet-3065	98	21	amino	amino	NOUN
admet-3065	98	22	acid	acid	NOUN
admet-3065	98	23	/	/	SYM
admet-3065	98	24	peptide	peptide	NOUN
admet-3065	98	25	conjugates	conjugate	NOUN
admet-3065	98	26	,	,	PUNCT
admet-3065	98	27	all	all	PRON
admet-3065	98	28	of	of	ADP
admet-3065	98	29	which	which	PRON
admet-3065	98	30	show	show	VERB
admet-3065	98	31	promising	promise	VERB
admet-3065	98	32	gene	gene	NOUN
admet-3065	98	33	delivery	delivery	NOUN
admet-3065	98	34	capabilities	capability	NOUN
admet-3065	99	1	[	[	X
admet-3065	99	2	52	52	NUM
admet-3065	99	3	]	]	PUNCT
admet-3065	99	4	.	.	PUNCT
admet-3065	100	1	monovalent	monovalent	NOUN
admet-3065	100	2	cationic	cationic	NOUN
admet-3065	100	3	lipids	lipid	NOUN
admet-3065	100	4	monovalent	monovalent	NOUN
admet-3065	100	5	cationic	cationic	NOUN
admet-3065	100	6	lipids	lipid	NOUN
admet-3065	100	7	have	have	VERB
admet-3065	100	8	a	a	DET
admet-3065	100	9	single	single	ADJ
admet-3065	100	10	positively	positively	ADV
admet-3065	100	11	charged	charge	VERB
admet-3065	100	12	headgroup	headgroup	NOUN
admet-3065	100	13	,	,	PUNCT
admet-3065	100	14	which	which	PRON
admet-3065	100	15	interacts	interact	VERB
admet-3065	100	16	electrostatically	electrostatically	ADV
admet-3065	100	17	with	with	ADP
admet-3065	100	18	negatively	negatively	ADV
admet-3065	100	19	charged	charge	VERB
admet-3065	100	20	nucleic	nucleic	ADJ
admet-3065	100	21	acids	acid	NOUN
admet-3065	100	22	.	.	PUNCT
admet-3065	101	1	dna	dna	PROPN
admet-3065	101	2	binding	bind	VERB
admet-3065	101	3	by	by	ADP
admet-3065	101	4	the	the	DET
admet-3065	101	5	vector	vector	NOUN
admet-3065	101	6	requires	require	VERB
admet-3065	101	7	a	a	DET
admet-3065	101	8	headgroup	headgroup	NOUN
admet-3065	101	9	capable	capable	ADJ
admet-3065	101	10	of	of	ADP
admet-3065	101	11	maintaining	maintain	VERB
admet-3065	101	12	a	a	DET
admet-3065	101	13	positive	positive	ADJ
admet-3065	101	14	charge	charge	NOUN
admet-3065	101	15	at	at	ADP
admet-3065	101	16	physiological	physiological	ADJ
admet-3065	101	17	ph	ph	NOUN
admet-3065	101	18	.	.	PUNCT
admet-3065	102	1	the	the	DET
admet-3065	102	2	charge	charge	NOUN
admet-3065	102	3	is	be	AUX
admet-3065	102	4	most	most	ADV
admet-3065	102	5	often	often	ADV
admet-3065	102	6	located	locate	VERB
admet-3065	102	7	on	on	ADP
admet-3065	102	8	amino	amino	ADJ
admet-3065	102	9	groups	group	NOUN
admet-3065	102	10	,	,	PUNCT
admet-3065	102	11	as	as	SCONJ
admet-3065	102	12	is	be	AUX
admet-3065	102	13	the	the	DET
admet-3065	102	14	case	case	NOUN
admet-3065	102	15	for	for	ADP
admet-3065	102	16	the	the	DET
admet-3065	102	17	'	'	PUNCT
admet-3065	102	18	early	early	ADJ
admet-3065	102	19	'	'	PUNCT
admet-3065	102	20	vectors	vector	NOUN
admet-3065	102	21	of	of	ADP
admet-3065	102	22	figure	figure	NOUN
admet-3065	102	23	3	3	NUM
admet-3065	102	24	.	.	PUNCT
admet-3065	103	1	however	however	ADV
admet-3065	103	2	,	,	PUNCT
admet-3065	103	3	other	other	ADJ
admet-3065	103	4	charged	charge	VERB
admet-3065	103	5	groups	group	NOUN
admet-3065	103	6	have	have	AUX
admet-3065	103	7	since	since	ADV
admet-3065	103	8	been	be	AUX
admet-3065	103	9	employed	employ	VERB
admet-3065	103	10	.	.	PUNCT
admet-3065	104	1	thus	thus	ADV
admet-3065	104	2	,	,	PUNCT
admet-3065	104	3	before	before	ADP
admet-3065	104	4	dealing	deal	VERB
admet-3065	104	5	more	more	ADV
admet-3065	104	6	extensively	extensively	ADV
admet-3065	104	7	with	with	ADP
admet-3065	104	8	amino	amino	NOUN
admet-3065	104	9	-	-	PUNCT
admet-3065	104	10	based	base	VERB
admet-3065	104	11	head	head	NOUN
admet-3065	104	12	groups	group	NOUN
admet-3065	104	13	,	,	PUNCT
admet-3065	104	14	it	it	PRON
admet-3065	104	15	is	be	AUX
admet-3065	104	16	worth	worth	ADJ
admet-3065	104	17	briefly	briefly	ADV
admet-3065	104	18	considering	consider	VERB
admet-3065	104	19	the	the	DET
admet-3065	104	20	other	other	ADJ
admet-3065	104	21	elements	element	NOUN
admet-3065	104	22	shown	show	VERB
admet-3065	104	23	capable	capable	ADJ
admet-3065	104	24	of	of	ADP
admet-3065	104	25	binding	bind	VERB
admet-3065	104	26	plasmids	plasmid	NOUN
admet-3065	104	27	.	.	PUNCT
admet-3065	105	1	phosphonium	phosphonium	NOUN
admet-3065	105	2	groups	group	NOUN
admet-3065	105	3	as	as	ADV
admet-3065	105	4	well	well	ADV
admet-3065	105	5	as	as	ADP
admet-3065	105	6	arsonium	arsonium	NOUN
admet-3065	105	7	groups	group	NOUN
admet-3065	105	8	(	(	PUNCT
admet-3065	105	9	which	which	PRON
admet-3065	105	10	,	,	PUNCT
admet-3065	105	11	unlike	unlike	ADP
admet-3065	105	12	arsenic(iii	arsenic(iii	NOUN
admet-3065	105	13	)	)	PUNCT
admet-3065	105	14	compounds	compound	NOUN
admet-3065	105	15	,	,	PUNCT
admet-3065	105	16	are	be	AUX
admet-3065	105	17	not	not	PART
admet-3065	105	18	toxic	toxic	ADJ
admet-3065	105	19	)	)	PUNCT
admet-3065	105	20	have	have	AUX
admet-3065	105	21	been	be	AUX
admet-3065	105	22	used	use	VERB
admet-3065	105	23	to	to	PART
admet-3065	105	24	convey	convey	VERB
admet-3065	105	25	the	the	DET
admet-3065	105	26	positive	positive	ADJ
admet-3065	105	27	charge	charge	NOUN
admet-3065	105	28	of	of	ADP
admet-3065	105	29	cationic	cationic	ADJ
admet-3065	105	30	lipids	lipid	NOUN
admet-3065	105	31	,	,	PUNCT
admet-3065	105	32	which	which	PRON
admet-3065	105	33	incorporate	incorporate	VERB
admet-3065	105	34	phosphonate	phosphonate	ADJ
admet-3065	105	35	linkers	linker	NOUN
admet-3065	105	36	(	(	PUNCT
admet-3065	105	37	as	as	ADP
admet-3065	105	38	in	in	ADP
admet-3065	105	39	natural	natural	ADJ
admet-3065	105	40	phospholipids	phospholipid	NOUN
admet-3065	105	41	)	)	PUNCT
admet-3065	106	1	[	[	X
admet-3065	106	2	53,54	53,54	NUM
admet-3065	106	3	]	]	X
admet-3065	106	4	.	.	PUNCT
admet-3065	107	1	the	the	DET
admet-3065	107	2	order	order	NOUN
admet-3065	107	3	arsenic	arsenic	VERB
admet-3065	107	4	>	>	X
admet-3065	107	5	phosphorous	phosphorous	ADJ
admet-3065	107	6	>	>	X
admet-3065	107	7	nitrogen	nitrogen	NOUN
admet-3065	107	8	was	be	AUX
admet-3065	107	9	observed	observe	VERB
admet-3065	107	10	in	in	ADP
admet-3065	107	11	vitro	vitro	X
admet-3065	107	12	testing	testing	NOUN
admet-3065	107	13	of	of	ADP
admet-3065	107	14	the	the	DET
admet-3065	107	15	analogues	analogue	NOUN
admet-3065	107	16	,	,	PUNCT
admet-3065	107	17	with	with	ADP
admet-3065	107	18	the	the	DET
admet-3065	107	19	phosphonium	phosphonium	NOUN
admet-3065	107	20	and	and	CCONJ
admet-3065	107	21	arsonium	arsonium	NOUN
admet-3065	107	22	vectors	vector	NOUN
admet-3065	107	23	being	be	AUX
admet-3065	107	24	less	less	ADV
admet-3065	107	25	cytotoxic	cytotoxic	ADJ
admet-3065	107	26	than	than	ADP
admet-3065	107	27	the	the	DET
admet-3065	107	28	ammonium	ammonium	NOUN
admet-3065	107	29	-	-	PUNCT
admet-3065	107	30	based	base	VERB
admet-3065	107	31	lipid	lipid	NOUN
admet-3065	107	32	[	[	X
admet-3065	107	33	55	55	NUM
admet-3065	107	34	]	]	PUNCT
admet-3065	107	35	.	.	PUNCT
admet-3065	108	1	further	far	ADV
admet-3065	108	2	,	,	PUNCT
admet-3065	108	3	cationic	cationic	ADJ
admet-3065	108	4	phosphonolipids	phosphonolipid	NOUN
admet-3065	108	5	were	be	AUX
admet-3065	108	6	found	find	VERB
admet-3065	108	7	to	to	PART
admet-3065	108	8	be	be	AUX
admet-3065	108	9	effective	effective	ADJ
admet-3065	108	10	in	in	ADP
admet-3065	108	11	mouse	mouse	NOUN
admet-3065	108	12	lungs	lung	NOUN
admet-3065	108	13	in	in	ADP
admet-3065	108	14	vivo	vivo	NOUN
admet-3065	108	15	after	after	ADP
admet-3065	108	16	intratracheal	intratracheal	NOUN
admet-3065	108	17	as	as	ADV
admet-3065	108	18	well	well	ADV
admet-3065	108	19	as	as	ADP
admet-3065	108	20	intravenous	intravenous	ADJ
admet-3065	108	21	administration	administration	NOUN
admet-3065	108	22	[	[	X
admet-3065	108	23	56	56	NUM
admet-3065	108	24	]	]	PUNCT
admet-3065	108	25	.	.	PUNCT
admet-3065	109	1	dotma	dotma	PROPN
admet-3065	109	2	n-[1-(2,3	n-[1-(2,3	NOUN
admet-3065	109	3	-	-	PUNCT
admet-3065	109	4	dioleyloxy)propyl]-n	dioleyloxy)propyl]-n	NOUN
admet-3065	109	5	,	,	PUNCT
admet-3065	109	6	n	n	CCONJ
admet-3065	109	7	,	,	PUNCT
admet-3065	109	8	n	n	CCONJ
admet-3065	109	9	-	-	PUNCT
admet-3065	109	10	trimethylammonium	trimethylammonium	NOUN
admet-3065	109	11	chloride	chloride	NOUN
admet-3065	109	12	,	,	PUNCT
admet-3065	109	13	or	or	CCONJ
admet-3065	109	14	dotma	dotma	NOUN
admet-3065	109	15	,	,	PUNCT
admet-3065	109	16	is	be	AUX
admet-3065	109	17	one	one	NUM
admet-3065	109	18	of	of	ADP
admet-3065	109	19	the	the	DET
admet-3065	109	20	first	first	ADJ
admet-3065	109	21	cationic	cationic	ADJ
admet-3065	109	22	lipids	lipid	NOUN
admet-3065	109	23	synthesized	synthesize	VERB
admet-3065	109	24	and	and	CCONJ
admet-3065	109	25	commercially	commercially	ADV
admet-3065	109	26	available	available	ADJ
admet-3065	109	27	for	for	ADP
admet-3065	109	28	gene	gene	NOUN
admet-3065	109	29	delivery	delivery	NOUN
admet-3065	109	30	(	(	PUNCT
admet-3065	109	31	figure	figure	NOUN
admet-3065	109	32	3a	3a	NUM
admet-3065	109	33	)	)	PUNCT
admet-3065	109	34	.	.	PUNCT
admet-3065	110	1	it	it	PRON
admet-3065	110	2	has	have	VERB
admet-3065	110	3	two	two	NUM
admet-3065	110	4	unsaturated	unsaturated	ADJ
admet-3065	110	5	oleoyl	oleoyl	ADJ
admet-3065	110	6	chains	chain	NOUN
admet-3065	110	7	(	(	PUNCT
admet-3065	110	8	c18	c18	NOUN
admet-3065	110	9	:	:	PUNCT
admet-3065	110	10	δ9	δ9	NOUN
admet-3065	110	11	)	)	PUNCT
admet-3065	110	12	linked	link	VERB
admet-3065	110	13	by	by	ADP
admet-3065	110	14	an	an	DET
admet-3065	110	15	ether	ether	NOUN
admet-3065	110	16	bond	bond	NOUN
admet-3065	110	17	to	to	ADP
admet-3065	110	18	a	a	DET
admet-3065	110	19	three	three	NUM
admet-3065	110	20	-	-	PUNCT
admet-3065	110	21	carbon	carbon	NOUN
admet-3065	110	22	glycerol	glycerol	NOUN
admet-3065	110	23	backbone	backbone	NOUN
admet-3065	110	24	,	,	PUNCT
admet-3065	110	25	and	and	CCONJ
admet-3065	110	26	the	the	DET
admet-3065	110	27	cationic	cationic	ADJ
admet-3065	110	28	head	head	NOUN
admet-3065	110	29	group	group	NOUN
admet-3065	110	30	is	be	AUX
admet-3065	110	31	a	a	DET
admet-3065	110	32	quaternary	quaternary	ADJ
admet-3065	110	33	amine	amine	NOUN
admet-3065	110	34	.	.	PUNCT
admet-3065	111	1	compared	compare	VERB
admet-3065	111	2	with	with	ADP
admet-3065	111	3	other	other	ADJ
admet-3065	111	4	gene	gene	NOUN
admet-3065	111	5	transfer	transfer	NOUN
admet-3065	111	6	methods	method	NOUN
admet-3065	111	7	in	in	ADP
admet-3065	111	8	the	the	DET
admet-3065	111	9	late	late	ADJ
admet-3065	111	10	1980s	1980	NOUN
admet-3065	111	11	,	,	PUNCT
admet-3065	111	12	dotma	dotma	NOUN
admet-3065	111	13	was	be	AUX
admet-3065	111	14	found	find	VERB
admet-3065	111	15	to	to	PART
admet-3065	111	16	be	be	AUX
admet-3065	111	17	up	up	ADP
admet-3065	111	18	to	to	PART
admet-3065	111	19	100	100	NUM
admet-3065	111	20	-	-	NUM
admet-3065	111	21	fold	fold	VERB
admet-3065	111	22	more	more	ADV
admet-3065	111	23	efficient	efficient	ADJ
admet-3065	111	24	at	at	ADP
admet-3065	111	25	gene	gene	NOUN
admet-3065	111	26	delivery	delivery	NOUN
admet-3065	111	27	than	than	ADP
admet-3065	111	28	methods	method	NOUN
admet-3065	111	29	such	such	ADJ
admet-3065	111	30	as	as	ADP
admet-3065	111	31	deae	deae	NOUN
admet-3065	111	32	-	-	PUNCT
admet-3065	111	33	dextran	dextran	NOUN
admet-3065	111	34	coprecipitation	coprecipitation	NOUN
admet-3065	111	35	or	or	CCONJ
admet-3065	111	36	calcium	calcium	NOUN
admet-3065	111	37	phosphate	phosphate	NOUN
admet-3065	112	1	[	[	X
admet-3065	112	2	19	19	NUM
admet-3065	112	3	]	]	PUNCT
admet-3065	112	4	.	.	PUNCT
admet-3065	113	1	e.	e.	PROPN
admet-3065	113	2	j.	j.	PROPN
admet-3065	113	3	saleh	saleh	PROPN
admet-3065	113	4	et	et	PROPN
admet-3065	113	5	al	al	PROPN
admet-3065	113	6	.	.	PROPN
admet-3065	113	7	admet	admet	PROPN
admet-3065	113	8	&	&	CCONJ
admet-3065	113	9	dmpk	dmpk	PROPN
admet-3065	113	10	00(0	00(0	PROPN
admet-3065	113	11	)	)	PUNCT
admet-3065	113	12	(	(	PUNCT
admet-3065	113	13	2025	2025	NUM
admet-3065	113	14	)	)	PUNCT
admet-3065	113	15	3065	3065	NUM
admet-3065	113	16	6	6	NUM
admet-3065	113	17	figure	figure	NOUN
admet-3065	113	18	3	3	NUM
admet-3065	113	19	.	.	PUNCT
admet-3065	114	1	chemical	chemical	NOUN
admet-3065	114	2	structures	structure	NOUN
admet-3065	114	3	of	of	ADP
admet-3065	114	4	representative	representative	ADJ
admet-3065	114	5	cationic	cationic	NOUN
admet-3065	114	6	lipids	lipid	NOUN
admet-3065	114	7	used	use	VERB
admet-3065	114	8	in	in	ADP
admet-3065	114	9	gene	gene	NOUN
admet-3065	114	10	delivery	delivery	NOUN
admet-3065	114	11	.	.	PUNCT
admet-3065	115	1	the	the	DET
admet-3065	115	2	molecular	molecular	ADJ
admet-3065	115	3	components	component	NOUN
admet-3065	115	4	of	of	ADP
admet-3065	115	5	each	each	DET
admet-3065	115	6	lipid	lipid	NOUN
admet-3065	115	7	are	be	AUX
admet-3065	115	8	categorized	categorize	VERB
admet-3065	115	9	into	into	ADP
admet-3065	115	10	three	three	NUM
admet-3065	115	11	regions	region	NOUN
admet-3065	115	12	:	:	PUNCT
admet-3065	115	13	hydrophobic	hydrophobic	NOUN
admet-3065	115	14	tails	tail	NOUN
admet-3065	115	15	(	(	PUNCT
admet-3065	115	16	green	green	ADJ
admet-3065	115	17	)	)	PUNCT
admet-3065	115	18	,	,	PUNCT
admet-3065	115	19	linker	linker	NOUN
admet-3065	115	20	(	(	PUNCT
admet-3065	115	21	blue	blue	ADJ
admet-3065	115	22	)	)	PUNCT
admet-3065	115	23	,	,	PUNCT
admet-3065	115	24	and	and	CCONJ
admet-3065	115	25	cationic	cationic	ADJ
admet-3065	115	26	head	head	NOUN
admet-3065	115	27	group	group	NOUN
admet-3065	115	28	(	(	PUNCT
admet-3065	115	29	orange	orange	PROPN
admet-3065	115	30	)	)	PUNCT
admet-3065	115	31	.	.	PUNCT
admet-3065	116	1	structures	structure	NOUN
admet-3065	116	2	shown	show	VERB
admet-3065	116	3	include	include	VERB
admet-3065	116	4	:	:	PUNCT
admet-3065	116	5	(	(	PUNCT
admet-3065	116	6	a	a	X
admet-3065	116	7	)	)	PUNCT
admet-3065	116	8	dotma	dotma	NOUN
admet-3065	116	9	,	,	PUNCT
admet-3065	116	10	(	(	PUNCT
admet-3065	116	11	b	b	X
admet-3065	116	12	)	)	PUNCT
admet-3065	116	13	ac	ac	NOUN
admet-3065	116	14	-	-	NOUN
admet-3065	116	15	chol	chol	NOUN
admet-3065	116	16	,	,	PUNCT
admet-3065	116	17	(	(	PUNCT
admet-3065	116	18	c	c	X
admet-3065	116	19	)	)	PUNCT
admet-3065	116	20	mc	mc	NOUN
admet-3065	116	21	-	-	PUNCT
admet-3065	116	22	chol	chol	NOUN
admet-3065	116	23	,	,	PUNCT
admet-3065	116	24	(	(	PUNCT
admet-3065	116	25	d	d	X
admet-3065	116	26	)	)	PUNCT
admet-3065	116	27	dc	dc	PROPN
admet-3065	116	28	-	-	PUNCT
admet-3065	116	29	chol	chol	NOUN
admet-3065	116	30	,	,	PUNCT
admet-3065	116	31	(	(	PUNCT
admet-3065	116	32	e	e	NOUN
admet-3065	116	33	)	)	PUNCT
admet-3065	116	34	dogs	dog	NOUN
admet-3065	116	35	,	,	PUNCT
admet-3065	116	36	and	and	CCONJ
admet-3065	116	37	(	(	PUNCT
admet-3065	116	38	f	f	X
admet-3065	116	39	)	)	PUNCT
admet-3065	116	40	bgtc	bgtc	NOUN
admet-3065	116	41	.	.	PUNCT
admet-3065	117	1	these	these	DET
admet-3065	117	2	structures	structure	NOUN
admet-3065	117	3	differ	differ	VERB
admet-3065	117	4	in	in	ADP
admet-3065	117	5	tail	tail	NOUN
admet-3065	117	6	saturation	saturation	NOUN
admet-3065	117	7	,	,	PUNCT
admet-3065	117	8	head	head	NOUN
admet-3065	117	9	group	group	NOUN
admet-3065	117	10	type	type	NOUN
admet-3065	117	11	,	,	PUNCT
admet-3065	117	12	and	and	CCONJ
admet-3065	117	13	linker	linker	NOUN
admet-3065	117	14	chemistry	chemistry	NOUN
admet-3065	117	15	,	,	PUNCT
admet-3065	117	16	which	which	PRON
admet-3065	117	17	influence	influence	VERB
admet-3065	117	18	their	their	PRON
admet-3065	117	19	biophysical	biophysical	ADJ
admet-3065	117	20	properties	property	NOUN
admet-3065	117	21	and	and	CCONJ
admet-3065	117	22	transfection	transfection	NOUN
admet-3065	117	23	efficiency	efficiency	NOUN
admet-3065	117	24	.	.	PUNCT
admet-3065	118	1	dotma	dotma	PROPN
admet-3065	118	2	was	be	AUX
admet-3065	118	3	commercialized	commercialize	VERB
admet-3065	118	4	as	as	ADP
admet-3065	118	5	lipofectin	lipofectin	NOUN
admet-3065	118	6	,	,	PUNCT
admet-3065	118	7	which	which	PRON
admet-3065	118	8	was	be	AUX
admet-3065	118	9	mixed	mix	VERB
admet-3065	118	10	with	with	ADP
admet-3065	118	11	dope	dope	NOUN
admet-3065	118	12	at	at	ADP
admet-3065	118	13	a	a	DET
admet-3065	118	14	1:1	1:1	NUM
admet-3065	118	15	ratio	ratio	NOUN
admet-3065	118	16	to	to	PART
admet-3065	118	17	maximize	maximize	VERB
admet-3065	118	18	transfection	transfection	NOUN
admet-3065	118	19	efficiency	efficiency	NOUN
admet-3065	118	20	.	.	PUNCT
admet-3065	119	1	as	as	SCONJ
admet-3065	119	2	lipofectin	lipofectin	NOUN
admet-3065	119	3	was	be	AUX
admet-3065	119	4	still	still	ADV
admet-3065	119	5	being	be	AUX
admet-3065	119	6	optimized	optimize	VERB
admet-3065	119	7	,	,	PUNCT
admet-3065	119	8	researchers	researcher	NOUN
admet-3065	119	9	began	begin	VERB
admet-3065	119	10	modifying	modify	VERB
admet-3065	119	11	dotma	dotma	NOUN
admet-3065	119	12	to	to	PART
admet-3065	119	13	reduce	reduce	VERB
admet-3065	119	14	toxicity	toxicity	NOUN
admet-3065	119	15	and	and	CCONJ
admet-3065	119	16	improve	improve	VERB
admet-3065	119	17	efficiency	efficiency	NOUN
admet-3065	119	18	across	across	ADP
admet-3065	119	19	the	the	DET
admet-3065	119	20	three	three	NUM
admet-3065	119	21	main	main	ADJ
admet-3065	119	22	parts	part	NOUN
admet-3065	119	23	of	of	ADP
admet-3065	119	24	the	the	DET
admet-3065	119	25	lipid	lipid	ADJ
admet-3065	119	26	head	head	NOUN
admet-3065	119	27	group	group	NOUN
admet-3065	119	28	,	,	PUNCT
admet-3065	119	29	linker	linker	NOUN
admet-3065	119	30	,	,	PUNCT
admet-3065	119	31	and	and	CCONJ
admet-3065	119	32	hydrocarbon	hydrocarbon	NOUN
admet-3065	119	33	chains	chain	NOUN
admet-3065	119	34	[	[	X
admet-3065	119	35	57	57	NUM
admet-3065	119	36	-	-	SYM
admet-3065	119	37	59	59	NUM
admet-3065	119	38	]	]	PUNCT
admet-3065	119	39	.	.	PUNCT
admet-3065	120	1	admet	admet	PROPN
admet-3065	120	2	&	&	CCONJ
admet-3065	120	3	dmpk	dmpk	PROPN
admet-3065	120	4	00(0	00(0	PROPN
admet-3065	120	5	)	)	PUNCT
admet-3065	120	6	(	(	PUNCT
admet-3065	120	7	2025	2025	NUM
admet-3065	120	8	)	)	PUNCT
admet-3065	120	9	3065	3065	NUM
admet-3065	120	10	liposome	liposome	NOUN
admet-3065	120	11	-	-	PUNCT
admet-3065	120	12	mediated	mediate	VERB
admet-3065	120	13	gene	gene	NOUN
admet-3065	120	14	delivery	delivery	NOUN
admet-3065	120	15	doi	doi	NOUN
admet-3065	120	16	:	:	PUNCT
admet-3065	120	17	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	120	18	7	7	NUM
admet-3065	120	19	dotap	dotap	NOUN
admet-3065	120	20	[	[	X
admet-3065	120	21	1,2	1,2	NUM
admet-3065	120	22	-	-	ADJ
admet-3065	120	23	bis(oleoyloxy)-3-(trimethylammonio)propane	bis(oleoyloxy)-3-(trimethylammonio)propane	NOUN
admet-3065	120	24	]	]	X
admet-3065	120	25	,	,	PUNCT
admet-3065	120	26	or	or	CCONJ
admet-3065	120	27	dotap	dotap	NOUN
admet-3065	120	28	,	,	PUNCT
admet-3065	120	29	was	be	AUX
admet-3065	120	30	synthesized	synthesize	VERB
admet-3065	120	31	by	by	ADP
admet-3065	120	32	leventis	leventis	NOUN
admet-3065	120	33	and	and	CCONJ
admet-3065	120	34	silvius	silvius	NOUN
admet-3065	120	35	in	in	ADP
admet-3065	120	36	1990	1990	NUM
admet-3065	120	37	[	[	X
admet-3065	120	38	60	60	NUM
admet-3065	120	39	]	]	PUNCT
admet-3065	120	40	.	.	PUNCT
admet-3065	121	1	it	it	PRON
admet-3065	121	2	is	be	AUX
admet-3065	121	3	structurally	structurally	ADV
admet-3065	121	4	similar	similar	ADJ
admet-3065	121	5	to	to	ADP
admet-3065	121	6	dotma	dotma	PROPN
admet-3065	121	7	but	but	CCONJ
admet-3065	121	8	differs	differ	VERB
admet-3065	121	9	in	in	ADP
admet-3065	121	10	that	that	DET
admet-3065	121	11	ester	ester	NOUN
admet-3065	121	12	bonds	bond	NOUN
admet-3065	121	13	,	,	PUNCT
admet-3065	121	14	rather	rather	ADV
admet-3065	121	15	than	than	ADP
admet-3065	121	16	ether	ether	ADJ
admet-3065	121	17	bonds	bond	NOUN
admet-3065	121	18	,	,	PUNCT
admet-3065	121	19	link	link	VERB
admet-3065	121	20	the	the	DET
admet-3065	121	21	oleoyl	oleoyl	ADJ
admet-3065	121	22	chains	chain	NOUN
admet-3065	121	23	to	to	ADP
admet-3065	121	24	the	the	DET
admet-3065	121	25	glycerol	glycerol	NOUN
admet-3065	121	26	backbone	backbone	NOUN
admet-3065	121	27	.	.	PUNCT
admet-3065	122	1	ester	ester	NOUN
admet-3065	122	2	bonds	bond	NOUN
admet-3065	122	3	were	be	AUX
admet-3065	122	4	believed	believe	VERB
admet-3065	122	5	to	to	PART
admet-3065	122	6	render	render	VERB
admet-3065	122	7	dotap	dotap	NOUN
admet-3065	122	8	biodegradable	biodegradable	ADJ
admet-3065	122	9	,	,	PUNCT
admet-3065	122	10	thereby	thereby	ADV
admet-3065	122	11	reducing	reduce	VERB
admet-3065	122	12	cytotoxicity	cytotoxicity	NOUN
admet-3065	122	13	.	.	PUNCT
admet-3065	123	1	however	however	ADV
admet-3065	123	2	,	,	PUNCT
admet-3065	123	3	it	it	PRON
admet-3065	123	4	was	be	AUX
admet-3065	123	5	discovered	discover	VERB
admet-3065	123	6	that	that	SCONJ
admet-3065	123	7	the	the	DET
admet-3065	123	8	transfection	transfection	NOUN
admet-3065	123	9	efficiency	efficiency	NOUN
admet-3065	123	10	and	and	CCONJ
admet-3065	123	11	cytotoxicity	cytotoxicity	NOUN
admet-3065	123	12	of	of	ADP
admet-3065	123	13	dotap	dotap	NOUN
admet-3065	123	14	/	/	SYM
admet-3065	123	15	dope	dope	NOUN
admet-3065	123	16	preparations	preparation	NOUN
admet-3065	123	17	were	be	AUX
admet-3065	123	18	comparable	comparable	ADJ
admet-3065	123	19	with	with	ADP
admet-3065	123	20	those	those	PRON
admet-3065	123	21	of	of	ADP
admet-3065	123	22	dotma	dotma	NOUN
admet-3065	123	23	/	/	SYM
admet-3065	123	24	dope	dope	NOUN
admet-3065	123	25	complexes	complex	NOUN
admet-3065	123	26	[	[	PUNCT
admet-3065	123	27	61	61	NUM
admet-3065	123	28	]	]	PUNCT
admet-3065	123	29	.	.	PUNCT
admet-3065	124	1	dc	dc	PROPN
admet-3065	124	2	-	-	PUNCT
admet-3065	124	3	chol	chol	PROPN
admet-3065	124	4	3β[n-(n',n'-dimethylaminoethane)-carbamoyl]cholesterol	3β[n-(n',n'-dimethylaminoethane)-carbamoyl]cholesterol	PROPN
admet-3065	124	5	,	,	PUNCT
admet-3065	124	6	or	or	CCONJ
admet-3065	124	7	dc	dc	PROPN
admet-3065	124	8	-	-	PUNCT
admet-3065	124	9	chol	chol	NOUN
admet-3065	124	10	,	,	PUNCT
admet-3065	124	11	was	be	AUX
admet-3065	124	12	synthesized	synthesize	VERB
admet-3065	124	13	by	by	ADP
admet-3065	124	14	gao	gao	PROPN
admet-3065	124	15	and	and	CCONJ
admet-3065	124	16	huang	huang	PROPN
admet-3065	124	17	in	in	ADP
admet-3065	124	18	1991	1991	NUM
admet-3065	124	19	[	[	X
admet-3065	124	20	18	18	NUM
admet-3065	124	21	]	]	PUNCT
admet-3065	124	22	(	(	PUNCT
admet-3065	124	23	figure	figure	NOUN
admet-3065	124	24	3d	3d	NUM
admet-3065	124	25	)	)	PUNCT
admet-3065	124	26	.	.	PUNCT
admet-3065	125	1	dc	dc	PROPN
admet-3065	125	2	-	-	PUNCT
admet-3065	125	3	chol	chol	NOUN
admet-3065	125	4	contains	contain	VERB
admet-3065	125	5	a	a	DET
admet-3065	125	6	cholesterol	cholesterol	NOUN
admet-3065	125	7	moiety	moiety	NOUN
admet-3065	125	8	attached	attach	VERB
admet-3065	125	9	via	via	ADP
admet-3065	125	10	an	an	DET
admet-3065	125	11	ester	ester	NOUN
admet-3065	125	12	bond	bond	NOUN
admet-3065	125	13	to	to	ADP
admet-3065	125	14	a	a	DET
admet-3065	125	15	hydrolysable	hydrolysable	ADJ
admet-3065	125	16	dimethylethylenediamine	dimethylethylenediamine	NOUN
admet-3065	125	17	.	.	PUNCT
admet-3065	126	1	cholesterol	cholesterol	NOUN
admet-3065	126	2	was	be	AUX
admet-3065	126	3	chosen	choose	VERB
admet-3065	126	4	for	for	ADP
admet-3065	126	5	its	its	PRON
admet-3065	126	6	biocompatibility	biocompatibility	NOUN
admet-3065	126	7	and	and	CCONJ
admet-3065	126	8	lipid	lipid	NOUN
admet-3065	126	9	-	-	PUNCT
admet-3065	126	10	stabilizing	stabilize	VERB
admet-3065	126	11	effects	effect	NOUN
admet-3065	126	12	.	.	PUNCT
admet-3065	127	1	unlike	unlike	ADP
admet-3065	127	2	cationic	cationic	ADJ
admet-3065	127	3	liposomes	liposome	NOUN
admet-3065	127	4	that	that	PRON
admet-3065	127	5	are	be	AUX
admet-3065	127	6	composed	compose	VERB
admet-3065	127	7	of	of	ADP
admet-3065	127	8	fully	fully	ADV
admet-3065	127	9	charged	charge	VERB
admet-3065	127	10	quaternary	quaternary	ADJ
admet-3065	127	11	amines	amine	NOUN
admet-3065	127	12	(	(	PUNCT
admet-3065	127	13	e.g.	e.g.	ADV
admet-3065	127	14	dotma	dotma	NOUN
admet-3065	127	15	and	and	CCONJ
admet-3065	127	16	dotap	dotap	NOUN
admet-3065	127	17	)	)	PUNCT
admet-3065	127	18	,	,	PUNCT
admet-3065	127	19	dc	dc	PROPN
admet-3065	127	20	-	-	PUNCT
admet-3065	127	21	chol	chol	NOUN
admet-3065	127	22	contains	contain	VERB
admet-3065	127	23	a	a	DET
admet-3065	127	24	tertiary	tertiary	ADJ
admet-3065	127	25	amine	amine	NOUN
admet-3065	127	26	that	that	PRON
admet-3065	127	27	is	be	AUX
admet-3065	127	28	half	half	ADV
admet-3065	127	29	-	-	PUNCT
admet-3065	127	30	charged	charge	VERB
admet-3065	127	31	at	at	ADP
admet-3065	127	32	physiological	physiological	ADJ
admet-3065	127	33	ph	ph	NOUN
admet-3065	127	34	7.4	7.4	NUM
admet-3065	127	35	,	,	PUNCT
admet-3065	127	36	which	which	PRON
admet-3065	127	37	is	be	AUX
admet-3065	127	38	thought	think	VERB
admet-3065	127	39	to	to	PART
admet-3065	127	40	reduce	reduce	VERB
admet-3065	127	41	lipoplex	lipoplex	NOUN
admet-3065	127	42	aggregation	aggregation	NOUN
admet-3065	127	43	and	and	CCONJ
admet-3065	127	44	facilitate	facilitate	VERB
admet-3065	127	45	transgene	transgene	ADJ
admet-3065	127	46	expression	expression	NOUN
admet-3065	127	47	.	.	PUNCT
admet-3065	128	1	the	the	DET
admet-3065	128	2	reduced	reduced	ADJ
admet-3065	128	3	overall	overall	ADJ
admet-3065	128	4	charge	charge	NOUN
admet-3065	128	5	of	of	ADP
admet-3065	128	6	dc	dc	PROPN
admet-3065	128	7	-	-	PUNCT
admet-3065	128	8	chol	chol	NOUN
admet-3065	128	9	liposomes	liposome	NOUN
admet-3065	128	10	also	also	ADV
admet-3065	128	11	favours	favour	VERB
admet-3065	128	12	dna	dna	PROPN
admet-3065	128	13	dissociation	dissociation	NOUN
admet-3065	128	14	,	,	PUNCT
admet-3065	128	15	which	which	PRON
admet-3065	128	16	is	be	AUX
admet-3065	128	17	a	a	DET
admet-3065	128	18	prerequisite	prerequisite	NOUN
admet-3065	128	19	for	for	ADP
admet-3065	128	20	efficient	efficient	ADJ
admet-3065	128	21	transfection	transfection	NOUN
admet-3065	129	1	[	[	X
admet-3065	129	2	62,63	62,63	NOUN
admet-3065	129	3	]	]	PUNCT
admet-3065	129	4	.	.	PUNCT
admet-3065	130	1	multivalent	multivalent	PROPN
admet-3065	130	2	cationic	cationic	NOUN
admet-3065	130	3	lipids	lipids	ADP
admet-3065	130	4	dospa	dospa	NOUN
admet-3065	130	5	2,3	2,3	NUM
admet-3065	130	6	-	-	PUNCT
admet-3065	130	7	dioleyloxy	dioleyloxy	NOUN
admet-3065	130	8	-	-	PUNCT
admet-3065	130	9	n-[2(sperminecarboxamido)ethyl]-n	n-[2(sperminecarboxamido)ethyl]-n	NOUN
admet-3065	130	10	,	,	PUNCT
admet-3065	130	11	n	n	CCONJ
admet-3065	130	12	-	-	PUNCT
admet-3065	130	13	dimethyl	dimethyl	NOUN
admet-3065	130	14	-	-	PUNCT
admet-3065	130	15	l	l	NOUN
admet-3065	130	16	-	-	ADJ
admet-3065	130	17	propanaminium	propanaminium	NOUN
admet-3065	130	18	trifluoroacetate	trifluoroacetate	NOUN
admet-3065	130	19	,	,	PUNCT
admet-3065	130	20	or	or	CCONJ
admet-3065	130	21	dospa	dospa	NOUN
admet-3065	130	22	,	,	PUNCT
admet-3065	130	23	is	be	AUX
admet-3065	130	24	a	a	DET
admet-3065	130	25	cationic	cationic	ADJ
admet-3065	130	26	lipid	lipid	NOUN
admet-3065	130	27	derivative	derivative	NOUN
admet-3065	130	28	of	of	ADP
admet-3065	130	29	dotma	dotma	NOUN
admet-3065	130	30	.	.	PUNCT
admet-3065	131	1	the	the	DET
admet-3065	131	2	dospa	dospa	NOUN
admet-3065	131	3	structure	structure	NOUN
admet-3065	131	4	is	be	AUX
admet-3065	131	5	analogous	analogous	ADJ
admet-3065	131	6	to	to	ADP
admet-3065	131	7	that	that	PRON
admet-3065	131	8	of	of	ADP
admet-3065	131	9	dotma	dotma	NOUN
admet-3065	131	10	,	,	PUNCT
admet-3065	131	11	except	except	SCONJ
admet-3065	131	12	for	for	ADP
admet-3065	131	13	a	a	DET
admet-3065	131	14	spermine	spermine	NOUN
admet-3065	131	15	group	group	NOUN
admet-3065	131	16	appended	append	VERB
admet-3065	131	17	to	to	ADP
admet-3065	131	18	the	the	DET
admet-3065	131	19	hydrophobic	hydrophobic	NOUN
admet-3065	131	20	chains	chain	NOUN
admet-3065	131	21	via	via	ADP
admet-3065	131	22	a	a	DET
admet-3065	131	23	peptide	peptide	NOUN
admet-3065	131	24	bond	bond	NOUN
admet-3065	131	25	.	.	PUNCT
admet-3065	132	1	in	in	ADP
admet-3065	132	2	a	a	DET
admet-3065	132	3	3:1	3:1	NUM
admet-3065	132	4	ratio	ratio	NOUN
admet-3065	132	5	with	with	ADP
admet-3065	132	6	dope	dope	NOUN
admet-3065	132	7	,	,	PUNCT
admet-3065	132	8	dospa	dospa	NOUN
admet-3065	132	9	is	be	AUX
admet-3065	132	10	sold	sell	VERB
admet-3065	132	11	commercially	commercially	ADV
admet-3065	132	12	under	under	ADP
admet-3065	132	13	the	the	DET
admet-3065	132	14	name	name	NOUN
admet-3065	132	15	lipofectamine	lipofectamine	NOUN
admet-3065	132	16	.	.	PUNCT
admet-3065	133	1	the	the	DET
admet-3065	133	2	spermine	spermine	NOUN
admet-3065	133	3	functional	functional	PROPN
admet-3065	133	4	group	group	NOUN
admet-3065	133	5	enables	enable	VERB
admet-3065	133	6	dna	dna	NOUN
admet-3065	133	7	condensation	condensation	NOUN
admet-3065	133	8	in	in	ADP
admet-3065	133	9	liposomes	liposome	NOUN
admet-3065	133	10	,	,	PUNCT
admet-3065	133	11	most	most	ADV
admet-3065	133	12	likely	likely	ADJ
admet-3065	133	13	due	due	ADP
admet-3065	133	14	to	to	ADP
admet-3065	133	15	its	its	PRON
admet-3065	133	16	multiple	multiple	ADJ
admet-3065	133	17	ammonium	ammonium	NOUN
admet-3065	133	18	groups	group	NOUN
admet-3065	133	19	,	,	PUNCT
admet-3065	133	20	which	which	PRON
admet-3065	133	21	can	can	AUX
admet-3065	133	22	interact	interact	VERB
admet-3065	133	23	with	with	ADP
admet-3065	133	24	dna	dna	PROPN
admet-3065	133	25	bases	basis	NOUN
admet-3065	133	26	via	via	ADP
admet-3065	133	27	hydrogen	hydrogen	NOUN
admet-3065	133	28	bonds	bond	NOUN
admet-3065	133	29	and	and	CCONJ
admet-3065	133	30	wrap	wrap	VERB
admet-3065	133	31	around	around	ADP
admet-3065	133	32	the	the	DET
admet-3065	133	33	major	major	ADJ
admet-3065	133	34	groove	groove	NOUN
admet-3065	133	35	to	to	PART
admet-3065	133	36	interact	interact	VERB
admet-3065	133	37	with	with	ADP
admet-3065	133	38	opposite	opposite	ADJ
admet-3065	133	39	-	-	PUNCT
admet-3065	133	40	strand	strand	ADJ
admet-3065	133	41	complementary	complementary	ADJ
admet-3065	133	42	bases	basis	NOUN
admet-3065	133	43	[	[	X
admet-3065	133	44	64	64	NUM
admet-3065	133	45	]	]	PUNCT
admet-3065	133	46	.	.	PUNCT
admet-3065	134	1	dogs	dog	NOUN
admet-3065	134	2	di	di	NOUN
admet-3065	134	3	-	-	PUNCT
admet-3065	134	4	octadecyl	octadecyl	NOUN
admet-3065	134	5	-	-	PUNCT
admet-3065	134	6	amido	amido	NOUN
admet-3065	134	7	-	-	PUNCT
admet-3065	134	8	glycyl	glycyl	NOUN
admet-3065	134	9	-	-	PUNCT
admet-3065	134	10	spermine	spermine	NOUN
admet-3065	134	11	,	,	PUNCT
admet-3065	134	12	or	or	CCONJ
admet-3065	134	13	dogs	dog	NOUN
admet-3065	134	14	,	,	PUNCT
admet-3065	134	15	is	be	AUX
admet-3065	134	16	a	a	DET
admet-3065	134	17	structural	structural	ADJ
admet-3065	134	18	analog	analog	NOUN
admet-3065	134	19	of	of	ADP
admet-3065	134	20	dospa	dospa	NOUN
admet-3065	134	21	(	(	PUNCT
admet-3065	134	22	figure	figure	NOUN
admet-3065	134	23	3e	3e	NOUN
admet-3065	134	24	)	)	PUNCT
admet-3065	134	25	,	,	PUNCT
admet-3065	134	26	but	but	CCONJ
admet-3065	134	27	dogs	dog	NOUN
admet-3065	134	28	has	have	AUX
admet-3065	134	29	saturated	saturate	VERB
admet-3065	134	30	alkyl	alkyl	ADJ
admet-3065	134	31	chains	chain	NOUN
admet-3065	134	32	,	,	PUNCT
admet-3065	134	33	and	and	CCONJ
admet-3065	134	34	they	they	PRON
admet-3065	134	35	are	be	AUX
admet-3065	134	36	linked	link	VERB
admet-3065	134	37	to	to	ADP
admet-3065	134	38	the	the	DET
admet-3065	134	39	head	head	NOUN
admet-3065	134	40	group	group	NOUN
admet-3065	134	41	via	via	ADP
admet-3065	134	42	a	a	DET
admet-3065	134	43	peptide	peptide	NOUN
admet-3065	134	44	bond	bond	NOUN
admet-3065	134	45	,	,	PUNCT
admet-3065	134	46	without	without	ADP
admet-3065	134	47	the	the	DET
admet-3065	134	48	quaternary	quaternary	ADJ
admet-3065	134	49	amine	amine	NOUN
admet-3065	134	50	.	.	PUNCT
admet-3065	135	1	dogs	dog	NOUN
admet-3065	135	2	,	,	PUNCT
admet-3065	135	3	which	which	PRON
admet-3065	135	4	is	be	AUX
admet-3065	135	5	marketed	market	VERB
admet-3065	135	6	as	as	ADP
admet-3065	135	7	transfectam	transfectam	NOUN
admet-3065	135	8	,	,	PUNCT
admet-3065	135	9	has	have	AUX
admet-3065	135	10	been	be	AUX
admet-3065	135	11	found	find	VERB
admet-3065	135	12	to	to	PART
admet-3065	135	13	give	give	VERB
admet-3065	135	14	transgene	transgene	ADJ
admet-3065	135	15	expression	expression	NOUN
admet-3065	135	16	levels	level	NOUN
admet-3065	135	17	over	over	ADP
admet-3065	135	18	10	10	NUM
admet-3065	135	19	times	time	NOUN
admet-3065	135	20	higher	high	ADJ
admet-3065	135	21	than	than	ADP
admet-3065	135	22	that	that	PRON
admet-3065	135	23	using	use	VERB
admet-3065	135	24	calcium	calcium	NOUN
admet-3065	135	25	phosphate	phosphate	NOUN
admet-3065	135	26	transfections	transfection	NOUN
admet-3065	135	27	[	[	X
admet-3065	135	28	65	65	NUM
admet-3065	135	29	]	]	PUNCT
admet-3065	135	30	.	.	PUNCT
admet-3065	136	1	dogs	dog	NOUN
admet-3065	136	2	is	be	AUX
admet-3065	136	3	poorly	poorly	ADV
admet-3065	136	4	cytotoxic	cytotoxic	ADJ
admet-3065	136	5	but	but	CCONJ
admet-3065	136	6	efficiently	efficiently	ADV
admet-3065	136	7	condenses	condense	VERB
admet-3065	136	8	dna	dna	PROPN
admet-3065	136	9	due	due	ADP
admet-3065	136	10	to	to	ADP
admet-3065	136	11	the	the	DET
admet-3065	136	12	close	close	ADJ
admet-3065	136	13	interaction	interaction	NOUN
admet-3065	136	14	between	between	ADP
admet-3065	136	15	the	the	DET
admet-3065	136	16	spermine	spermine	NOUN
admet-3065	136	17	head	head	NOUN
admet-3065	136	18	group	group	NOUN
admet-3065	136	19	and	and	CCONJ
admet-3065	136	20	dna	dna	PROPN
admet-3065	136	21	.	.	PUNCT
admet-3065	137	1	dogs	dog	NOUN
admet-3065	137	2	also	also	ADV
admet-3065	137	3	buffers	buffer	VERB
admet-3065	137	4	the	the	DET
admet-3065	137	5	endosomal	endosomal	ADJ
admet-3065	137	6	compartment	compartment	NOUN
admet-3065	137	7	and	and	CCONJ
admet-3065	137	8	protects	protect	VERB
admet-3065	137	9	the	the	DET
admet-3065	137	10	delivered	deliver	VERB
admet-3065	137	11	dna	dna	NOUN
admet-3065	137	12	from	from	ADP
admet-3065	137	13	degradation	degradation	NOUN
admet-3065	137	14	by	by	ADP
admet-3065	137	15	ph	ph	ADJ
admet-3065	137	16	-	-	ADJ
admet-3065	137	17	sensitive	sensitive	ADJ
admet-3065	137	18	nucleases	nuclease	NOUN
admet-3065	137	19	[	[	X
admet-3065	137	20	66	66	NUM
admet-3065	137	21	]	]	PUNCT
admet-3065	137	22	.	.	PUNCT
admet-3065	138	1	neutral	neutral	ADJ
admet-3065	138	2	and	and	CCONJ
admet-3065	138	3	helper	helper	NOUN
admet-3065	138	4	lipids	lipids	ADP
admet-3065	138	5	lipid	lipid	NOUN
admet-3065	138	6	formulations	formulation	NOUN
admet-3065	138	7	for	for	ADP
admet-3065	138	8	gene	gene	NOUN
admet-3065	138	9	delivery	delivery	NOUN
admet-3065	138	10	typically	typically	ADV
admet-3065	138	11	include	include	VERB
admet-3065	138	12	a	a	DET
admet-3065	138	13	combination	combination	NOUN
admet-3065	138	14	of	of	ADP
admet-3065	138	15	charged	charge	VERB
admet-3065	138	16	lipids	lipid	NOUN
admet-3065	138	17	and	and	CCONJ
admet-3065	138	18	neutral	neutral	ADJ
admet-3065	138	19	helper	helper	NOUN
admet-3065	138	20	lipids	lipids	ADP
admet-3065	138	21	such	such	ADJ
admet-3065	138	22	as	as	ADP
admet-3065	138	23	dioleoylphosphatidylethanolamine	dioleoylphosphatidylethanolamine	NOUN
admet-3065	138	24	(	(	PUNCT
admet-3065	138	25	dope	dope	NOUN
admet-3065	138	26	)	)	PUNCT
admet-3065	138	27	or	or	CCONJ
admet-3065	138	28	dioleoylphosphatidylcholine	dioleoylphosphatidylcholine	NOUN
admet-3065	138	29	(	(	PUNCT
admet-3065	138	30	dopc	dopc	NOUN
admet-3065	138	31	)	)	PUNCT
admet-3065	139	1	[	[	X
admet-3065	139	2	57,58	57,58	X
admet-3065	139	3	]	]	X
admet-3065	139	4	(	(	PUNCT
admet-3065	139	5	table	table	NOUN
admet-3065	139	6	2	2	NUM
admet-3065	139	7	)	)	PUNCT
admet-3065	139	8	.	.	PUNCT
admet-3065	140	1	table	table	NOUN
admet-3065	140	2	2	2	NUM
admet-3065	140	3	.	.	PUNCT
admet-3065	140	4	functions	function	NOUN
admet-3065	140	5	and	and	CCONJ
admet-3065	140	6	structural	structural	ADJ
admet-3065	140	7	features	feature	NOUN
admet-3065	140	8	of	of	ADP
admet-3065	140	9	common	common	ADJ
admet-3065	140	10	helper	helper	NOUN
admet-3065	140	11	lipids	lipid	NOUN
admet-3065	140	12	in	in	ADP
admet-3065	140	13	nanocarrier	nanocarrier	NOUN
admet-3065	140	14	formulations	formulation	NOUN
admet-3065	140	15	.	.	PUNCT
admet-3065	141	1	helper	helper	NOUN
admet-3065	141	2	lipid	lipid	PROPN
admet-3065	141	3	function	function	NOUN
admet-3065	141	4	structure	structure	NOUN
admet-3065	141	5	comments	comment	NOUN
admet-3065	141	6	dope	dope	VERB
admet-3065	141	7	endosomal	endosomal	ADJ
admet-3065	141	8	escape	escape	NOUN
admet-3065	141	9	,	,	PUNCT
admet-3065	141	10	fusogenicity	fusogenicity	NOUN
admet-3065	141	11	unsaturated	unsaturate	VERB
admet-3065	141	12	,	,	PUNCT
admet-3065	141	13	small	small	ADJ
admet-3065	141	14	headgroup	headgroup	NOUN
admet-3065	141	15	forms	form	NOUN
admet-3065	141	16	inverted	invert	VERB
admet-3065	141	17	hexagonal	hexagonal	ADJ
admet-3065	141	18	phase	phase	NOUN
admet-3065	141	19	at	at	ADP
admet-3065	141	20	acidic	acidic	ADJ
admet-3065	141	21	ph	ph	ADJ
admet-3065	141	22	dopc	dopc	NOUN
admet-3065	141	23	membrane	membrane	NOUN
admet-3065	141	24	stability	stability	NOUN
admet-3065	141	25	zwitterionic	zwitterionic	NOUN
admet-3065	141	26	,	,	PUNCT
admet-3065	141	27	bulky	bulky	ADJ
admet-3065	141	28	choline	choline	NOUN
admet-3065	141	29	less	less	ADV
admet-3065	141	30	efficient	efficient	ADJ
admet-3065	141	31	than	than	SCONJ
admet-3065	141	32	dope	dope	VERB
admet-3065	141	33	cholesterol	cholesterol	NOUN
admet-3065	141	34	membrane	membrane	NOUN
admet-3065	141	35	packing	packing	NOUN
admet-3065	141	36	,	,	PUNCT
admet-3065	141	37	structural	structural	ADJ
admet-3065	141	38	integrity	integrity	NOUN
admet-3065	141	39	rigid	rigid	ADJ
admet-3065	141	40	steroid	steroid	NOUN
admet-3065	141	41	ring	ring	NOUN
admet-3065	141	42	enhances	enhance	VERB
admet-3065	141	43	stability	stability	NOUN
admet-3065	141	44	and	and	CCONJ
admet-3065	141	45	uptake	uptake	ADJ
admet-3065	141	46	peg	peg	NOUN
admet-3065	141	47	-	-	PUNCT
admet-3065	141	48	lipids	lipids	ADJ
admet-3065	141	49	stealth	stealth	ADJ
admet-3065	141	50	behaviour	behaviour	NOUN
admet-3065	141	51	hydrophilic	hydrophilic	ADJ
admet-3065	141	52	polymer	polymer	NOUN
admet-3065	141	53	prolongs	prolong	VERB
admet-3065	141	54	circulation	circulation	NOUN
admet-3065	141	55	,	,	PUNCT
admet-3065	141	56	reduces	reduce	VERB
admet-3065	141	57	immune	immune	ADJ
admet-3065	141	58	clearance	clearance	NOUN
admet-3065	141	59	dope	dope	NOUN
admet-3065	141	60	is	be	AUX
admet-3065	141	61	the	the	DET
admet-3065	141	62	most	most	ADV
admet-3065	141	63	widely	widely	ADV
admet-3065	141	64	used	use	VERB
admet-3065	141	65	of	of	ADP
admet-3065	141	66	these	these	DET
admet-3065	141	67	neutral	neutral	ADJ
admet-3065	141	68	helper	helper	NOUN
admet-3065	141	69	lipids	lipids	ADP
admet-3065	141	70	[	[	X
admet-3065	141	71	67	67	NUM
admet-3065	141	72	]	]	PUNCT
admet-3065	141	73	.	.	PUNCT
admet-3065	142	1	experiments	experiment	NOUN
admet-3065	142	2	demonstrated	demonstrate	VERB
admet-3065	142	3	that	that	SCONJ
admet-3065	142	4	dope	dope	NOUN
admet-3065	142	5	is	be	AUX
admet-3065	142	6	more	more	ADV
admet-3065	142	7	effective	effective	ADJ
admet-3065	142	8	at	at	ADP
admet-3065	142	9	transfection	transfection	NOUN
admet-3065	142	10	than	than	ADP
admet-3065	142	11	dopc	dopc	NOUN
admet-3065	142	12	in	in	ADP
admet-3065	142	13	most	most	ADJ
admet-3065	142	14	cell	cell	NOUN
admet-3065	142	15	types	type	NOUN
admet-3065	142	16	because	because	SCONJ
admet-3065	142	17	it	it	PRON
admet-3065	142	18	can	can	AUX
admet-3065	142	19	adopt	adopt	VERB
admet-3065	142	20	an	an	DET
admet-3065	142	21	inverted	inverted	ADJ
admet-3065	142	22	hexagonal	hexagonal	ADJ
admet-3065	142	23	packing	packing	NOUN
admet-3065	142	24	arrangement	arrangement	NOUN
admet-3065	142	25	at	at	ADP
admet-3065	142	26	low	low	ADJ
admet-3065	142	27	ph	ph	NOUN
admet-3065	143	1	[	[	X
admet-3065	143	2	68	68	NUM
admet-3065	143	3	]	]	PUNCT
admet-3065	143	4	.	.	PUNCT
admet-3065	144	1	this	this	DET
admet-3065	144	2	inverted	inverted	ADJ
admet-3065	144	3	hexagonal	hexagonal	ADJ
admet-3065	144	4	structure	structure	NOUN
admet-3065	144	5	differs	differ	VERB
admet-3065	144	6	from	from	ADP
admet-3065	144	7	the	the	DET
admet-3065	144	8	lamellar	lamellar	ADJ
admet-3065	144	9	packing	packing	NOUN
admet-3065	144	10	e.	e.	PROPN
admet-3065	144	11	j.	j.	PROPN
admet-3065	144	12	saleh	saleh	PROPN
admet-3065	144	13	et	et	PROPN
admet-3065	144	14	al	al	PROPN
admet-3065	144	15	.	.	PROPN
admet-3065	144	16	admet	admet	PROPN
admet-3065	144	17	&	&	CCONJ
admet-3065	144	18	dmpk	dmpk	PROPN
admet-3065	144	19	00(0	00(0	PROPN
admet-3065	144	20	)	)	PUNCT
admet-3065	144	21	(	(	PUNCT
admet-3065	144	22	2025	2025	NUM
admet-3065	144	23	)	)	PUNCT
admet-3065	144	24	3065	3065	NUM
admet-3065	144	25	8	8	NUM
admet-3065	144	26	observed	observe	VERB
admet-3065	144	27	in	in	ADP
admet-3065	144	28	most	most	ADJ
admet-3065	144	29	dna	dna	NOUN
admet-3065	144	30	/	/	SYM
admet-3065	144	31	lipid	lipid	NOUN
admet-3065	144	32	complexes	complex	NOUN
admet-3065	144	33	and	and	CCONJ
admet-3065	144	34	resembles	resemble	VERB
admet-3065	144	35	a	a	DET
admet-3065	144	36	honeycomb	honeycomb	NOUN
admet-3065	144	37	of	of	ADP
admet-3065	144	38	tube	tube	NOUN
admet-3065	144	39	structures	structure	NOUN
admet-3065	144	40	that	that	PRON
admet-3065	144	41	trap	trap	VERB
admet-3065	144	42	dna	dna	NOUN
admet-3065	144	43	within	within	ADP
admet-3065	144	44	the	the	DET
admet-3065	144	45	tubes	tube	NOUN
admet-3065	144	46	via	via	ADP
admet-3065	144	47	electrostatic	electrostatic	ADJ
admet-3065	144	48	forces	force	NOUN
admet-3065	144	49	[	[	X
admet-3065	144	50	69	69	NUM
admet-3065	144	51	]	]	PUNCT
admet-3065	144	52	.	.	PUNCT
admet-3065	145	1	studies	study	NOUN
admet-3065	145	2	show	show	VERB
admet-3065	145	3	that	that	SCONJ
admet-3065	145	4	the	the	DET
admet-3065	145	5	hexagonal	hexagonal	ADJ
admet-3065	145	6	structure	structure	NOUN
admet-3065	145	7	induces	induce	VERB
admet-3065	145	8	the	the	DET
admet-3065	145	9	effective	effective	ADJ
admet-3065	145	10	release	release	NOUN
admet-3065	145	11	of	of	ADP
admet-3065	145	12	dna	dna	NOUN
admet-3065	145	13	from	from	ADP
admet-3065	145	14	endosomal	endosomal	ADJ
admet-3065	145	15	vesicles	vesicle	NOUN
admet-3065	145	16	by	by	ADP
admet-3065	145	17	destabilizing	destabilize	VERB
admet-3065	145	18	their	their	PRON
admet-3065	145	19	membranes	membrane	NOUN
admet-3065	145	20	[	[	X
admet-3065	145	21	70	70	NUM
admet-3065	145	22	-	-	SYM
admet-3065	145	23	73	73	NUM
admet-3065	145	24	]	]	PUNCT
admet-3065	145	25	.	.	PUNCT
admet-3065	146	1	cholesterol	cholesterol	NOUN
admet-3065	146	2	(	(	PUNCT
admet-3065	146	3	chol	chol	NOUN
admet-3065	146	4	)	)	PUNCT
admet-3065	146	5	is	be	AUX
admet-3065	146	6	another	another	DET
admet-3065	146	7	important	important	ADJ
admet-3065	146	8	helper	helper	NOUN
admet-3065	146	9	lipid	lipid	NOUN
admet-3065	146	10	that	that	PRON
admet-3065	146	11	helps	help	VERB
admet-3065	146	12	lipoplex	lipoplex	PROPN
admet-3065	146	13	function	function	NOUN
admet-3065	146	14	[	[	X
admet-3065	146	15	74	74	NUM
admet-3065	146	16	]	]	PUNCT
admet-3065	146	17	.	.	PUNCT
admet-3065	147	1	as	as	ADP
admet-3065	147	2	a	a	DET
admet-3065	147	3	neutral	neutral	ADJ
admet-3065	147	4	amphiphile	amphiphile	NOUN
admet-3065	147	5	,	,	PUNCT
admet-3065	147	6	chol	chol	NOUN
admet-3065	147	7	promotes	promote	VERB
admet-3065	147	8	membrane	membrane	NOUN
admet-3065	147	9	packing	packing	NOUN
admet-3065	147	10	and	and	CCONJ
admet-3065	147	11	structural	structural	ADJ
admet-3065	147	12	integrity	integrity	NOUN
admet-3065	147	13	without	without	ADP
admet-3065	147	14	direct	direct	ADJ
admet-3065	147	15	interaction	interaction	NOUN
admet-3065	147	16	with	with	ADP
admet-3065	147	17	nas	nas	PROPN
admet-3065	147	18	[	[	X
admet-3065	147	19	72	72	NUM
admet-3065	147	20	]	]	PUNCT
admet-3065	147	21	.	.	PUNCT
admet-3065	148	1	being	be	AUX
admet-3065	148	2	present	present	ADJ
admet-3065	148	3	in	in	ADP
admet-3065	148	4	lipoplex	lipoplex	PROPN
admet-3065	148	5	preparations	preparation	NOUN
admet-3065	148	6	enables	enable	VERB
admet-3065	148	7	it	it	PRON
admet-3065	148	8	to	to	PART
admet-3065	148	9	interact	interact	VERB
admet-3065	148	10	with	with	ADP
admet-3065	148	11	both	both	CCONJ
admet-3065	148	12	plasma	plasma	NOUN
admet-3065	148	13	and	and	CCONJ
admet-3065	148	14	endosomal	endosomal	ADJ
admet-3065	148	15	membranes	membrane	NOUN
admet-3065	148	16	,	,	PUNCT
admet-3065	148	17	thereby	thereby	ADV
admet-3065	148	18	increasing	increase	VERB
admet-3065	148	19	transfection	transfection	NOUN
admet-3065	148	20	efficiency	efficiency	NOUN
admet-3065	148	21	[	[	X
admet-3065	148	22	75	75	NUM
admet-3065	148	23	]	]	PUNCT
admet-3065	148	24	.	.	PUNCT
admet-3065	149	1	anionic	anionic	ADJ
admet-3065	149	2	lipids	lipids	ADJ
admet-3065	149	3	gene	gene	NOUN
admet-3065	149	4	delivery	delivery	NOUN
admet-3065	149	5	with	with	ADP
admet-3065	149	6	anionic	anionic	ADJ
admet-3065	149	7	lipids	lipid	NOUN
admet-3065	149	8	is	be	AUX
admet-3065	149	9	generally	generally	ADV
admet-3065	149	10	inefficient	inefficient	ADJ
admet-3065	149	11	.	.	PUNCT
admet-3065	150	1	the	the	DET
admet-3065	150	2	negatively	negatively	ADV
admet-3065	150	3	charged	charge	VERB
admet-3065	150	4	head	head	NOUN
admet-3065	150	5	groups	group	NOUN
admet-3065	150	6	of	of	ADP
admet-3065	150	7	anionic	anionic	ADJ
admet-3065	150	8	lipids	lipids	ADJ
admet-3065	150	9	repel	repel	NOUN
admet-3065	150	10	the	the	DET
admet-3065	150	11	phosphate	phosphate	ADJ
admet-3065	150	12	backbone	backbone	NOUN
admet-3065	150	13	of	of	ADP
admet-3065	150	14	dna	dna	PROPN
admet-3065	150	15	,	,	PUNCT
admet-3065	150	16	preventing	prevent	VERB
admet-3065	150	17	effective	effective	ADJ
admet-3065	150	18	dna	dna	NOUN
admet-3065	150	19	compaction	compaction	NOUN
admet-3065	150	20	[	[	X
admet-3065	150	21	39	39	NUM
admet-3065	150	22	]	]	PUNCT
admet-3065	150	23	.	.	PUNCT
admet-3065	151	1	despite	despite	SCONJ
admet-3065	151	2	this	this	DET
admet-3065	151	3	deficiency	deficiency	NOUN
admet-3065	151	4	,	,	PUNCT
admet-3065	151	5	anionic	anionic	ADJ
admet-3065	151	6	liposomes	liposome	NOUN
admet-3065	151	7	have	have	AUX
admet-3065	151	8	become	become	VERB
admet-3065	151	9	of	of	ADP
admet-3065	151	10	interest	interest	NOUN
admet-3065	151	11	as	as	ADP
admet-3065	151	12	promising	promise	VERB
admet-3065	151	13	gene	gene	NOUN
admet-3065	151	14	delivery	delivery	NOUN
admet-3065	151	15	vehicles	vehicle	NOUN
admet-3065	151	16	due	due	ADJ
admet-3065	151	17	to	to	ADP
admet-3065	151	18	the	the	DET
admet-3065	151	19	disadvantages	disadvantage	NOUN
admet-3065	151	20	of	of	ADP
admet-3065	151	21	cationic	cationic	ADJ
admet-3065	151	22	liposomes	liposome	NOUN
admet-3065	151	23	,	,	PUNCT
admet-3065	151	24	like	like	ADP
admet-3065	151	25	inactivation	inactivation	NOUN
admet-3065	151	26	by	by	ADP
admet-3065	151	27	serum	serum	NOUN
admet-3065	151	28	,	,	PUNCT
admet-3065	151	29	instability	instability	NOUN
admet-3065	151	30	in	in	ADP
admet-3065	151	31	storage	storage	NOUN
admet-3065	151	32	,	,	PUNCT
admet-3065	151	33	and	and	CCONJ
admet-3065	151	34	in	in	ADP
admet-3065	151	35	vitro	vitro	X
admet-3065	151	36	and	and	CCONJ
admet-3065	151	37	in	in	ADP
admet-3065	151	38	vivo	vivo	ADJ
admet-3065	151	39	cytotoxicity	cytotoxicity	NOUN
admet-3065	151	40	[	[	X
admet-3065	151	41	76	76	NUM
admet-3065	151	42	,	,	PUNCT
admet-3065	151	43	77	77	NUM
admet-3065	151	44	]	]	PUNCT
admet-3065	151	45	.	.	PUNCT
admet-3065	152	1	dna	dna	PROPN
admet-3065	152	2	-	-	PUNCT
admet-3065	152	3	containing	contain	VERB
admet-3065	152	4	liposomes	liposome	NOUN
admet-3065	152	5	can	can	AUX
admet-3065	152	6	be	be	AUX
admet-3065	152	7	assembled	assemble	VERB
admet-3065	152	8	by	by	ADP
admet-3065	152	9	anionic	anionic	ADJ
admet-3065	152	10	lipids	lipid	NOUN
admet-3065	152	11	using	use	VERB
admet-3065	152	12	divalent	divalent	ADJ
admet-3065	152	13	cations	cation	NOUN
admet-3065	152	14	,	,	PUNCT
admet-3065	152	15	which	which	PRON
admet-3065	152	16	neutralize	neutralize	VERB
admet-3065	152	17	electrostatic	electrostatic	ADJ
admet-3065	152	18	repulsion	repulsion	NOUN
admet-3065	152	19	between	between	ADP
admet-3065	152	20	negatively	negatively	ADV
admet-3065	152	21	charged	charge	VERB
admet-3065	152	22	lipids	lipid	NOUN
admet-3065	152	23	and	and	CCONJ
admet-3065	152	24	promote	promote	VERB
admet-3065	152	25	assembly	assembly	NOUN
admet-3065	152	26	of	of	ADP
admet-3065	152	27	lipoplexes	lipoplexe	NOUN
admet-3065	152	28	[	[	X
admet-3065	152	29	78	78	NUM
admet-3065	152	30	]	]	PUNCT
admet-3065	152	31	.	.	PUNCT
admet-3065	153	1	common	common	ADJ
admet-3065	153	2	anionic	anionic	ADJ
admet-3065	153	3	lipids	lipid	NOUN
admet-3065	153	4	are	be	AUX
admet-3065	153	5	naturally	naturally	ADV
admet-3065	153	6	occurring	occur	VERB
admet-3065	153	7	phospholipids	phospholipid	NOUN
admet-3065	153	8	in	in	ADP
admet-3065	153	9	cellular	cellular	ADJ
admet-3065	153	10	membranes	membrane	NOUN
admet-3065	153	11	,	,	PUNCT
admet-3065	153	12	for	for	ADP
admet-3065	153	13	instance	instance	NOUN
admet-3065	153	14	,	,	PUNCT
admet-3065	153	15	phosphatidic	phosphatidic	ADJ
admet-3065	153	16	acid	acid	NOUN
admet-3065	153	17	,	,	PUNCT
admet-3065	153	18	phosphatidylglycerol	phosphatidylglycerol	NOUN
admet-3065	153	19	,	,	PUNCT
admet-3065	153	20	and	and	CCONJ
admet-3065	153	21	phosphatidylserine	phosphatidylserine	VERB
admet-3065	153	22	[	[	X
admet-3065	153	23	79	79	NUM
admet-3065	153	24	]	]	PUNCT
admet-3065	153	25	.	.	PUNCT
admet-3065	154	1	the	the	DET
admet-3065	154	2	presence	presence	NOUN
admet-3065	154	3	of	of	ADP
admet-3065	154	4	phospholipids	phospholipid	NOUN
admet-3065	154	5	in	in	ADP
admet-3065	154	6	natural	natural	ADJ
admet-3065	154	7	cell	cell	NOUN
admet-3065	154	8	membranes	membrane	NOUN
admet-3065	154	9	is	be	AUX
admet-3065	154	10	associated	associate	VERB
admet-3065	154	11	with	with	ADP
admet-3065	154	12	compromised	compromise	VERB
admet-3065	154	13	clearance	clearance	NOUN
admet-3065	154	14	and	and	CCONJ
admet-3065	154	15	macrophage	macrophage	ADJ
admet-3065	154	16	phagocytosis	phagocytosis	NOUN
admet-3065	154	17	when	when	SCONJ
admet-3065	154	18	lipoplexes	lipoplexe	NOUN
admet-3065	154	19	carry	carry	VERB
admet-3065	154	20	a	a	DET
admet-3065	154	21	net	net	ADJ
admet-3065	154	22	negative	negative	ADJ
admet-3065	154	23	surface	surface	NOUN
admet-3065	154	24	charge	charge	NOUN
admet-3065	154	25	.	.	PUNCT
admet-3065	155	1	this	this	DET
admet-3065	155	2	characteristic	characteristic	NOUN
admet-3065	155	3	indicates	indicate	VERB
admet-3065	155	4	enhanced	enhanced	ADJ
admet-3065	155	5	biocompatibility	biocompatibility	NOUN
admet-3065	155	6	and	and	CCONJ
admet-3065	155	7	reduced	reduce	VERB
admet-3065	155	8	immunogenicity	immunogenicity	NOUN
admet-3065	155	9	,	,	PUNCT
admet-3065	155	10	making	make	VERB
admet-3065	155	11	anionic	anionic	ADJ
admet-3065	155	12	liposomes	liposome	NOUN
admet-3065	155	13	an	an	DET
admet-3065	155	14	attractive	attractive	ADJ
admet-3065	155	15	option	option	NOUN
admet-3065	155	16	for	for	ADP
admet-3065	155	17	gene	gene	NOUN
admet-3065	155	18	delivery	delivery	NOUN
admet-3065	156	1	[	[	X
admet-3065	156	2	80	80	NUM
admet-3065	156	3	]	]	PUNCT
admet-3065	156	4	.	.	PUNCT
admet-3065	157	1	detailed	detailed	ADJ
admet-3065	157	2	structural	structural	ADJ
admet-3065	157	3	components	component	NOUN
admet-3065	157	4	of	of	ADP
admet-3065	157	5	lipids	lipids	ADJ
admet-3065	157	6	head	head	NOUN
admet-3065	157	7	group	group	NOUN
admet-3065	157	8	cationic	cationic	ADJ
admet-3065	157	9	lipid	lipid	NOUN
admet-3065	157	10	polar	polar	ADJ
admet-3065	157	11	headgroups	headgroup	NOUN
admet-3065	157	12	primarily	primarily	ADV
admet-3065	157	13	facilitate	facilitate	VERB
admet-3065	157	14	the	the	DET
admet-3065	157	15	binding	binding	NOUN
admet-3065	157	16	of	of	ADP
admet-3065	157	17	anionic	anionic	ADJ
admet-3065	157	18	nucleic	nucleic	ADJ
admet-3065	157	19	acids	acid	NOUN
admet-3065	157	20	(	(	PUNCT
admet-3065	157	21	nas	nas	PROPN
admet-3065	157	22	)	)	PUNCT
admet-3065	157	23	through	through	ADP
admet-3065	157	24	electrostatic	electrostatic	ADJ
admet-3065	157	25	interactions	interaction	NOUN
admet-3065	157	26	,	,	PUNCT
admet-3065	157	27	forming	form	VERB
admet-3065	157	28	stable	stable	ADJ
admet-3065	157	29	lipoplex	lipoplex	NOUN
admet-3065	157	30	complexes	complex	NOUN
admet-3065	157	31	.	.	PUNCT
admet-3065	158	1	the	the	DET
admet-3065	158	2	structural	structural	ADJ
admet-3065	158	3	characteristics	characteristic	NOUN
admet-3065	158	4	of	of	ADP
admet-3065	158	5	these	these	DET
admet-3065	158	6	headgroups	headgroup	NOUN
admet-3065	158	7	,	,	PUNCT
admet-3065	158	8	such	such	ADJ
admet-3065	158	9	as	as	ADP
admet-3065	158	10	size	size	NOUN
admet-3065	158	11	,	,	PUNCT
admet-3065	158	12	charge	charge	NOUN
admet-3065	158	13	density	density	NOUN
admet-3065	158	14	,	,	PUNCT
admet-3065	158	15	and	and	CCONJ
admet-3065	158	16	chemical	chemical	NOUN
admet-3065	158	17	composition	composition	NOUN
admet-3065	158	18	,	,	PUNCT
admet-3065	158	19	significantly	significantly	ADV
admet-3065	158	20	impact	impact	VERB
admet-3065	158	21	lipoplex	lipoplex	PROPN
admet-3065	158	22	stability	stability	NOUN
admet-3065	158	23	,	,	PUNCT
admet-3065	158	24	na	na	ADP
admet-3065	158	25	condensation	condensation	NOUN
admet-3065	158	26	,	,	PUNCT
admet-3065	158	27	cellular	cellular	ADJ
admet-3065	158	28	membrane	membrane	NOUN
admet-3065	158	29	interactions	interaction	NOUN
admet-3065	158	30	,	,	PUNCT
admet-3065	158	31	and	and	CCONJ
admet-3065	158	32	endosomal	endosomal	ADJ
admet-3065	158	33	escape	escape	NOUN
admet-3065	158	34	efficiency	efficiency	NOUN
admet-3065	158	35	,	,	PUNCT
admet-3065	158	36	thereby	thereby	ADV
admet-3065	158	37	playing	play	VERB
admet-3065	158	38	a	a	DET
admet-3065	158	39	pivotal	pivotal	ADJ
admet-3065	158	40	role	role	NOUN
admet-3065	158	41	in	in	ADP
admet-3065	158	42	transfection	transfection	NOUN
admet-3065	158	43	efficacy	efficacy	NOUN
admet-3065	158	44	[	[	X
admet-3065	158	45	81	81	NUM
admet-3065	158	46	]	]	PUNCT
admet-3065	158	47	.	.	PUNCT
admet-3065	159	1	common	common	ADJ
admet-3065	159	2	polar	polar	ADJ
admet-3065	159	3	headgroup	headgroup	NOUN
admet-3065	159	4	classes	class	NOUN
admet-3065	159	5	include	include	VERB
admet-3065	159	6	quaternary	quaternary	ADJ
admet-3065	159	7	ammonium	ammonium	NOUN
admet-3065	159	8	salts	salt	NOUN
admet-3065	159	9	,	,	PUNCT
admet-3065	159	10	primary	primary	ADJ
admet-3065	159	11	,	,	PUNCT
admet-3065	159	12	secondary	secondary	ADJ
admet-3065	159	13	,	,	PUNCT
admet-3065	159	14	and	and	CCONJ
admet-3065	159	15	tertiary	tertiary	ADJ
admet-3065	159	16	amines	amine	NOUN
admet-3065	159	17	,	,	PUNCT
admet-3065	159	18	guanidinium	guanidinium	NOUN
admet-3065	159	19	groups	group	NOUN
admet-3065	159	20	,	,	PUNCT
admet-3065	159	21	heterocyclic	heterocyclic	ADJ
admet-3065	159	22	compounds	compound	NOUN
admet-3065	159	23	,	,	PUNCT
admet-3065	159	24	and	and	CCONJ
admet-3065	159	25	hybrid	hybrid	ADJ
admet-3065	159	26	structures	structure	NOUN
admet-3065	159	27	(	(	PUNCT
admet-3065	159	28	table	table	NOUN
admet-3065	159	29	3	3	NUM
admet-3065	159	30	)	)	PUNCT
admet-3065	159	31	.	.	PUNCT
admet-3065	160	1	advances	advance	NOUN
admet-3065	160	2	in	in	ADP
admet-3065	160	3	lipid	lipid	NOUN
admet-3065	160	4	design	design	NOUN
admet-3065	160	5	have	have	AUX
admet-3065	160	6	expanded	expand	VERB
admet-3065	160	7	this	this	DET
admet-3065	160	8	repertoire	repertoire	NOUN
admet-3065	160	9	,	,	PUNCT
admet-3065	160	10	with	with	ADP
admet-3065	160	11	biomacromolecular	biomacromolecular	ADJ
admet-3065	160	12	headgroups	headgroup	NOUN
admet-3065	160	13	enabling	enable	VERB
admet-3065	160	14	multifunctional	multifunctional	ADJ
admet-3065	160	15	delivery	delivery	NOUN
admet-3065	160	16	systems	system	NOUN
admet-3065	160	17	with	with	ADP
admet-3065	160	18	improved	improved	ADJ
admet-3065	160	19	properties	property	NOUN
admet-3065	160	20	[	[	X
admet-3065	160	21	82	82	NUM
admet-3065	160	22	]	]	PUNCT
admet-3065	160	23	.	.	PUNCT
admet-3065	161	1	table	table	NOUN
admet-3065	161	2	3	3	NUM
admet-3065	161	3	.	.	PUNCT
admet-3065	162	1	chemical	chemical	ADJ
admet-3065	162	2	classes	class	NOUN
admet-3065	162	3	of	of	ADP
admet-3065	162	4	cationic	cationic	ADJ
admet-3065	162	5	lipid	lipid	NOUN
admet-3065	162	6	headgroups	headgroup	NOUN
admet-3065	162	7	and	and	CCONJ
admet-3065	162	8	their	their	PRON
admet-3065	162	9	functional	functional	ADJ
admet-3065	162	10	characteristics	characteristic	NOUN
admet-3065	162	11	.	.	PUNCT
admet-3065	163	1	headgroup	headgroup	NOUN
admet-3065	163	2	type	type	NOUN
admet-3065	163	3	examples	example	NOUN
admet-3065	163	4	properties	property	NOUN
admet-3065	163	5	advantages	advantage	VERB
admet-3065	163	6	disadvantages	disadvantage	VERB
admet-3065	163	7	quaternary	quaternary	ADJ
admet-3065	163	8	ammonium	ammonium	NOUN
admet-3065	163	9	dotma	dotma	NOUN
admet-3065	163	10	,	,	PUNCT
admet-3065	163	11	dotap	dotap	NOUN
admet-3065	163	12	,	,	PUNCT
admet-3065	163	13	ddab	ddab	PROPN
admet-3065	163	14	permanently	permanently	ADV
admet-3065	163	15	charged	charge	VERB
admet-3065	163	16	at	at	ADP
admet-3065	163	17	ph	ph	PROPN
admet-3065	163	18	7	7	NUM
admet-3065	163	19	strong	strong	ADJ
admet-3065	163	20	dna	dna	NOUN
admet-3065	163	21	binding	bind	VERB
admet-3065	163	22	can	can	AUX
admet-3065	163	23	be	be	AUX
admet-3065	163	24	cytotoxic	cytotoxic	ADJ
admet-3065	163	25	primary	primary	ADJ
admet-3065	163	26	/	/	SYM
admet-3065	163	27	secondary	secondary	ADJ
admet-3065	163	28	/	/	SYM
admet-3065	163	29	tertiary	tertiary	ADJ
admet-3065	163	30	amines	amine	NOUN
admet-3065	163	31	dodap	dodap	ADJ
admet-3065	163	32	,	,	PUNCT
admet-3065	163	33	ctap	ctap	ADJ
admet-3065	163	34	weak	weak	ADJ
admet-3065	163	35	bases	basis	NOUN
admet-3065	163	36	,	,	PUNCT
admet-3065	163	37	phresponsive	phresponsive	ADJ
admet-3065	163	38	endosomal	endosomal	ADJ
admet-3065	163	39	escape	escape	VERB
admet-3065	163	40	lower	low	ADJ
admet-3065	163	41	binding	bind	VERB
admet-3065	163	42	affinity	affinity	NOUN
admet-3065	163	43	polyamines	polyamine	NOUN
admet-3065	163	44	dogs	dog	NOUN
admet-3065	163	45	,	,	PUNCT
admet-3065	163	46	dospa	dospa	NOUN
admet-3065	163	47	multiple	multiple	ADJ
admet-3065	163	48	amines	amine	NOUN
admet-3065	163	49	strong	strong	ADJ
admet-3065	163	50	condensation	condensation	NOUN
admet-3065	163	51	possible	possible	ADJ
admet-3065	163	52	aggregation	aggregation	NOUN
admet-3065	163	53	guanidinium	guanidinium	NOUN
admet-3065	163	54	bgsc	bgsc	NOUN
admet-3065	163	55	,	,	PUNCT
admet-3065	163	56	bgtc	bgtc	PROPN
admet-3065	163	57	,	,	PUNCT
admet-3065	163	58	dsgla	dsgla	PROPN
admet-3065	163	59	charge	charge	NOUN
admet-3065	163	60	delocalization	delocalization	NOUN
admet-3065	163	61	strong	strong	ADJ
admet-3065	163	62	binding	bind	VERB
admet-3065	163	63	may	may	AUX
admet-3065	163	64	hinder	hinder	VERB
admet-3065	163	65	release	release	VERB
admet-3065	163	66	heterocyclic	heterocyclic	ADJ
admet-3065	163	67	imidazole	imidazole	NOUN
admet-3065	163	68	,	,	PUNCT
admet-3065	163	69	pyridine	pyridine	ADJ
admet-3065	163	70	amphoteric	amphoteric	ADJ
admet-3065	163	71	efficient	efficient	ADJ
admet-3065	163	72	endosomal	endosomal	ADJ
admet-3065	163	73	escape	escape	NOUN
admet-3065	163	74	complex	complex	ADJ
admet-3065	163	75	synthesis	synthesis	NOUN
admet-3065	163	76	multivalent	multivalent	NOUN
admet-3065	163	77	cationic	cationic	NOUN
admet-3065	163	78	lipids	lipid	VERB
admet-3065	163	79	outperform	outperform	NOUN
admet-3065	163	80	monovalent	monovalent	NOUN
admet-3065	163	81	counterparts	counterpart	NOUN
admet-3065	163	82	in	in	ADP
admet-3065	163	83	transfection	transfection	NOUN
admet-3065	163	84	efficiency	efficiency	NOUN
admet-3065	163	85	due	due	ADP
admet-3065	163	86	to	to	ADP
admet-3065	163	87	their	their	PRON
admet-3065	163	88	enhanced	enhance	VERB
admet-3065	163	89	ability	ability	NOUN
admet-3065	163	90	to	to	PART
admet-3065	163	91	bind	bind	VERB
admet-3065	163	92	and	and	CCONJ
admet-3065	163	93	condense	condense	VERB
admet-3065	163	94	nas	nas	VERB
admet-3065	163	95	while	while	SCONJ
admet-3065	163	96	protecting	protect	VERB
admet-3065	163	97	them	they	PRON
admet-3065	163	98	from	from	ADP
admet-3065	163	99	intracellular	intracellular	ADJ
admet-3065	163	100	degradation	degradation	NOUN
admet-3065	163	101	[	[	X
admet-3065	163	102	83	83	NUM
admet-3065	163	103	]	]	PUNCT
admet-3065	163	104	.	.	PUNCT
admet-3065	164	1	the	the	DET
admet-3065	164	2	na	na	NOUN
admet-3065	164	3	-	-	ADJ
admet-3065	164	4	binding	binding	ADJ
admet-3065	164	5	efficiency	efficiency	NOUN
admet-3065	164	6	of	of	ADP
admet-3065	164	7	these	these	DET
admet-3065	164	8	headgroups	headgroup	NOUN
admet-3065	164	9	is	be	AUX
admet-3065	164	10	ph	ph	ADJ
admet-3065	164	11	-	-	ADJ
admet-3065	164	12	dependent	dependent	ADJ
admet-3065	164	13	,	,	PUNCT
admet-3065	164	14	as	as	SCONJ
admet-3065	164	15	protonation	protonation	NOUN
admet-3065	164	16	governs	govern	VERB
admet-3065	164	17	electrostatic	electrostatic	ADJ
admet-3065	164	18	interactions	interaction	NOUN
admet-3065	164	19	.	.	PUNCT
admet-3065	165	1	the	the	DET
admet-3065	165	2	acid	acid	PROPN
admet-3065	165	3	dissociation	dissociation	NOUN
admet-3065	165	4	constant	constant	ADJ
admet-3065	165	5	(	(	PUNCT
admet-3065	165	6	pka	pka	NOUN
admet-3065	165	7	)	)	PUNCT
admet-3065	165	8	of	of	ADP
admet-3065	165	9	the	the	DET
admet-3065	165	10	conjugate	conjugate	ADJ
admet-3065	165	11	acid	acid	NOUN
admet-3065	165	12	determines	determine	VERB
admet-3065	165	13	the	the	DET
admet-3065	165	14	protonation	protonation	NOUN
admet-3065	165	15	state	state	NOUN
admet-3065	165	16	:	:	PUNCT
admet-3065	165	17	headgroups	headgroup	NOUN
admet-3065	165	18	with	with	ADP
admet-3065	165	19	higher	high	ADJ
admet-3065	165	20	pka	pka	PROPN
admet-3065	165	21	values	value	NOUN
admet-3065	165	22	remain	remain	VERB
admet-3065	165	23	cationic	cationic	ADJ
admet-3065	165	24	at	at	ADP
admet-3065	165	25	physiological	physiological	ADJ
admet-3065	165	26	ph	ph	NOUN
admet-3065	165	27	,	,	PUNCT
admet-3065	165	28	promoting	promote	VERB
admet-3065	165	29	na	na	AUX
admet-3065	165	30	binding	bind	VERB
admet-3065	165	31	,	,	PUNCT
admet-3065	165	32	while	while	SCONJ
admet-3065	165	33	admet	admet	PROPN
admet-3065	165	34	&	&	CCONJ
admet-3065	165	35	dmpk	dmpk	PROPN
admet-3065	165	36	00(0	00(0	PROPN
admet-3065	165	37	)	)	PUNCT
admet-3065	165	38	(	(	PUNCT
admet-3065	165	39	2025	2025	NUM
admet-3065	165	40	)	)	PUNCT
admet-3065	165	41	3065	3065	NUM
admet-3065	165	42	liposome	liposome	NOUN
admet-3065	165	43	-	-	PUNCT
admet-3065	165	44	mediated	mediate	VERB
admet-3065	165	45	gene	gene	NOUN
admet-3065	165	46	delivery	delivery	NOUN
admet-3065	165	47	doi	doi	NOUN
admet-3065	165	48	:	:	PUNCT
admet-3065	165	49	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	165	50	9	9	NUM
admet-3065	165	51	deprotonation	deprotonation	NOUN
admet-3065	165	52	at	at	ADP
admet-3065	165	53	ph	ph	ADJ
admet-3065	165	54	values	value	NOUN
admet-3065	165	55	above	above	ADP
admet-3065	165	56	the	the	DET
admet-3065	165	57	pka	pka	NOUN
admet-3065	165	58	reduces	reduce	VERB
admet-3065	165	59	binding	bind	VERB
admet-3065	165	60	affinity	affinity	NOUN
admet-3065	165	61	.	.	PUNCT
admet-3065	166	1	protonatable	protonatable	ADJ
admet-3065	166	2	headgroups	headgroup	NOUN
admet-3065	166	3	also	also	ADV
admet-3065	166	4	provide	provide	VERB
admet-3065	166	5	buffering	buffering	NOUN
admet-3065	166	6	capacity	capacity	NOUN
admet-3065	166	7	,	,	PUNCT
admet-3065	166	8	facilitating	facilitate	VERB
admet-3065	166	9	endosomal	endosomal	ADJ
admet-3065	166	10	escape	escape	NOUN
admet-3065	166	11	via	via	ADP
admet-3065	166	12	the	the	DET
admet-3065	166	13	proton	proton	NOUN
admet-3065	166	14	sponge	sponge	NOUN
admet-3065	166	15	effect	effect	NOUN
admet-3065	166	16	.	.	PUNCT
admet-3065	167	1	in	in	ADP
admet-3065	167	2	the	the	DET
admet-3065	167	3	acidic	acidic	ADJ
admet-3065	167	4	endosomal	endosomal	ADJ
admet-3065	167	5	environment	environment	NOUN
admet-3065	167	6	(	(	PUNCT
admet-3065	167	7	ph	ph	VERB
admet-3065	167	8	5.5	5.5	NUM
admet-3065	167	9	to	to	PART
admet-3065	167	10	6	6	NUM
admet-3065	167	11	)	)	PUNCT
admet-3065	167	12	,	,	PUNCT
admet-3065	167	13	weakly	weakly	ADJ
admet-3065	167	14	basic	basic	ADJ
admet-3065	167	15	headgroups	headgroup	NOUN
admet-3065	167	16	protonate	protonate	VERB
admet-3065	167	17	,	,	PUNCT
admet-3065	167	18	inducing	induce	VERB
admet-3065	167	19	chloride	chloride	NOUN
admet-3065	167	20	influx	influx	NOUN
admet-3065	167	21	,	,	PUNCT
admet-3065	167	22	osmotic	osmotic	ADJ
admet-3065	167	23	swelling	swelling	NOUN
admet-3065	167	24	,	,	PUNCT
admet-3065	167	25	and	and	CCONJ
admet-3065	167	26	vesicle	vesicle	NOUN
admet-3065	167	27	rupture	rupture	NOUN
admet-3065	167	28	,	,	PUNCT
admet-3065	167	29	which	which	PRON
admet-3065	167	30	enhances	enhance	VERB
admet-3065	167	31	na	na	PART
admet-3065	167	32	release	release	NOUN
admet-3065	167	33	into	into	ADP
admet-3065	167	34	the	the	DET
admet-3065	167	35	cytosol	cytosol	NOUN
admet-3065	167	36	[	[	X
admet-3065	167	37	40	40	NUM
admet-3065	167	38	]	]	PUNCT
admet-3065	167	39	.	.	PUNCT
admet-3065	168	1	given	give	VERB
admet-3065	168	2	that	that	SCONJ
admet-3065	168	3	inefficient	inefficient	ADJ
admet-3065	168	4	endosomal	endosomal	ADJ
admet-3065	168	5	escape	escape	NOUN
admet-3065	168	6	is	be	AUX
admet-3065	168	7	a	a	DET
admet-3065	168	8	major	major	ADJ
admet-3065	168	9	barrier	barrier	NOUN
admet-3065	168	10	in	in	ADP
admet-3065	168	11	lipoplex	lipoplex	NOUN
admet-3065	168	12	-	-	PUNCT
admet-3065	168	13	mediated	mediate	VERB
admet-3065	168	14	gene	gene	NOUN
admet-3065	168	15	delivery	delivery	NOUN
admet-3065	168	16	,	,	PUNCT
admet-3065	168	17	buffering	buffering	NOUN
admet-3065	168	18	lipids	lipid	NOUN
admet-3065	168	19	are	be	AUX
admet-3065	168	20	often	often	ADV
admet-3065	168	21	favoured	favour	VERB
admet-3065	168	22	over	over	ADP
admet-3065	168	23	strongly	strongly	ADV
admet-3065	168	24	cationic	cationic	ADJ
admet-3065	168	25	,	,	PUNCT
admet-3065	168	26	non	non	ADJ
admet-3065	168	27	-	-	ADJ
admet-3065	168	28	buffering	buffering	ADJ
admet-3065	168	29	alternatives	alternative	NOUN
admet-3065	168	30	.	.	PUNCT
admet-3065	169	1	thus	thus	ADV
admet-3065	169	2	,	,	PUNCT
admet-3065	169	3	rational	rational	ADJ
admet-3065	169	4	headgroup	headgroup	NOUN
admet-3065	169	5	design	design	NOUN
admet-3065	169	6	,	,	PUNCT
admet-3065	169	7	optimizing	optimize	VERB
admet-3065	169	8	protonation	protonation	NOUN
admet-3065	169	9	behaviour	behaviour	NOUN
admet-3065	169	10	,	,	PUNCT
admet-3065	169	11	charge	charge	NOUN
admet-3065	169	12	density	density	NOUN
admet-3065	169	13	,	,	PUNCT
admet-3065	169	14	and	and	CCONJ
admet-3065	169	15	buffering	buffering	NOUN
admet-3065	169	16	capacity	capacity	NOUN
admet-3065	169	17	,	,	PUNCT
admet-3065	169	18	is	be	AUX
admet-3065	169	19	critical	critical	ADJ
admet-3065	169	20	for	for	ADP
admet-3065	169	21	developing	develop	VERB
admet-3065	169	22	efficient	efficient	ADJ
admet-3065	169	23	cationic	cationic	ADJ
admet-3065	169	24	lipid	lipid	NOUN
admet-3065	169	25	-	-	PUNCT
admet-3065	169	26	based	base	VERB
admet-3065	169	27	gene	gene	NOUN
admet-3065	169	28	delivery	delivery	NOUN
admet-3065	169	29	systems	system	NOUN
admet-3065	169	30	to	to	PART
admet-3065	169	31	maximize	maximize	VERB
admet-3065	169	32	transfection	transfection	NOUN
admet-3065	169	33	efficiency	efficiency	NOUN
admet-3065	169	34	and	and	CCONJ
admet-3065	169	35	therapeutic	therapeutic	ADJ
admet-3065	169	36	outcomes	outcome	NOUN
admet-3065	169	37	.	.	PUNCT
admet-3065	170	1	quaternary	quaternary	ADJ
admet-3065	170	2	ammonium	ammonium	NOUN
admet-3065	170	3	compounds	compound	VERB
admet-3065	170	4	quaternary	quaternary	ADJ
admet-3065	170	5	ammonium	ammonium	NOUN
admet-3065	170	6	(	(	PUNCT
admet-3065	170	7	nr⁺	nr⁺	ADJ
admet-3065	170	8	)	)	PUNCT
admet-3065	170	9	compounds	compound	NOUN
admet-3065	170	10	are	be	AUX
admet-3065	170	11	organic	organic	ADJ
admet-3065	170	12	cations	cation	NOUN
admet-3065	170	13	with	with	ADP
admet-3065	170	14	a	a	DET
admet-3065	170	15	permanently	permanently	ADV
admet-3065	170	16	charged	charge	VERB
admet-3065	170	17	nitrogen	nitrogen	NOUN
admet-3065	170	18	atom	atom	NOUN
admet-3065	170	19	covalently	covalently	ADV
admet-3065	170	20	linked	link	VERB
admet-3065	170	21	to	to	ADP
admet-3065	170	22	four	four	NUM
admet-3065	170	23	organic	organic	ADJ
admet-3065	170	24	substituents	substituent	NOUN
admet-3065	170	25	.	.	PUNCT
admet-3065	171	1	these	these	DET
admet-3065	171	2	headgroups	headgroup	NOUN
admet-3065	171	3	maintain	maintain	VERB
admet-3065	171	4	a	a	DET
admet-3065	171	5	stable	stable	ADJ
admet-3065	171	6	positive	positive	ADJ
admet-3065	171	7	charge	charge	NOUN
admet-3065	171	8	at	at	ADP
admet-3065	171	9	physiological	physiological	ADJ
admet-3065	171	10	ph	ph	NOUN
admet-3065	171	11	,	,	PUNCT
admet-3065	171	12	enabling	enable	VERB
admet-3065	171	13	robust	robust	ADJ
admet-3065	171	14	na	na	ADP
admet-3065	171	15	binding	binding	ADJ
admet-3065	171	16	and	and	CCONJ
admet-3065	171	17	sufficient	sufficient	ADJ
admet-3065	171	18	aqueous	aqueous	ADJ
admet-3065	171	19	solubility	solubility	NOUN
admet-3065	171	20	[	[	X
admet-3065	171	21	84	84	NUM
admet-3065	171	22	]	]	PUNCT
admet-3065	171	23	.	.	PUNCT
admet-3065	172	1	consequently	consequently	ADV
admet-3065	172	2	,	,	PUNCT
admet-3065	172	3	quaternary	quaternary	ADJ
admet-3065	172	4	ammonium	ammonium	NOUN
admet-3065	172	5	groups	group	NOUN
admet-3065	172	6	are	be	AUX
admet-3065	172	7	among	among	ADP
admet-3065	172	8	the	the	DET
admet-3065	172	9	most	most	ADV
admet-3065	172	10	widely	widely	ADV
admet-3065	172	11	adopted	adopt	VERB
admet-3065	172	12	polar	polar	ADJ
admet-3065	172	13	headgroups	headgroup	NOUN
admet-3065	172	14	in	in	ADP
admet-3065	172	15	cationic	cationic	ADJ
admet-3065	172	16	lipid	lipid	NOUN
admet-3065	172	17	design	design	NOUN
admet-3065	172	18	[	[	X
admet-3065	172	19	85	85	NUM
admet-3065	172	20	]	]	PUNCT
admet-3065	172	21	.	.	PUNCT
admet-3065	173	1	prominent	prominent	ADJ
admet-3065	173	2	examples	example	NOUN
admet-3065	173	3	of	of	ADP
admet-3065	173	4	gene	gene	NOUN
admet-3065	173	5	delivery	delivery	NOUN
admet-3065	173	6	vectors	vector	NOUN
admet-3065	173	7	include	include	VERB
admet-3065	173	8	1,2	1,2	NUM
admet-3065	173	9	-	-	PUNCT
admet-3065	173	10	di	di	NOUN
admet-3065	173	11	-	-	PUNCT
admet-3065	173	12	o	o	NOUN
admet-3065	173	13	-	-	PUNCT
admet-3065	173	14	octadecenyl-3	octadecenyl-3	NUM
admet-3065	173	15	-	-	PUNCT
admet-3065	173	16	trimethylammonium	trimethylammonium	NOUN
admet-3065	173	17	propane	propane	NOUN
admet-3065	173	18	(	(	PUNCT
admet-3065	173	19	dotma	dotma	PROPN
admet-3065	173	20	)	)	PUNCT
admet-3065	173	21	,	,	PUNCT
admet-3065	173	22	1,2	1,2	NUM
admet-3065	173	23	-	-	NOUN
admet-3065	173	24	dioleoyloxy-3-[trimethylammonium]-propane	dioleoyloxy-3-[trimethylammonium]-propane	NOUN
admet-3065	173	25	(	(	PUNCT
admet-3065	173	26	dotap	dotap	NOUN
admet-3065	173	27	)	)	PUNCT
admet-3065	173	28	,	,	PUNCT
admet-3065	173	29	dimethyldioctadecyl	dimethyldioctadecyl	VERB
admet-3065	173	30	ammonium	ammonium	NOUN
admet-3065	173	31	bromide	bromide	NOUN
admet-3065	173	32	(	(	PUNCT
admet-3065	173	33	ddab	ddab	PROPN
admet-3065	173	34	)	)	PUNCT
admet-3065	174	1	[	[	X
admet-3065	174	2	5	5	NUM
admet-3065	174	3	]	]	PUNCT
admet-3065	174	4	,	,	PUNCT
admet-3065	174	5	and	and	CCONJ
admet-3065	174	6	cetyltrimethyl	cetyltrimethyl	NOUN
admet-3065	174	7	ammonium	ammonium	NOUN
admet-3065	174	8	bromide	bromide	NOUN
admet-3065	174	9	(	(	PUNCT
admet-3065	174	10	ctab	ctab	NOUN
admet-3065	174	11	)	)	PUNCT
admet-3065	175	1	[	[	X
admet-3065	175	2	54	54	NUM
admet-3065	175	3	]	]	PUNCT
admet-3065	175	4	.	.	PUNCT
admet-3065	176	1	notably	notably	ADV
admet-3065	176	2	,	,	PUNCT
admet-3065	176	3	dotma	dotma	PROPN
admet-3065	176	4	,	,	PUNCT
admet-3065	176	5	the	the	DET
admet-3065	176	6	first	first	ADJ
admet-3065	176	7	synthesized	synthesize	VERB
admet-3065	176	8	quaternary	quaternary	ADJ
admet-3065	176	9	ammonium	ammonium	NOUN
admet-3065	176	10	-	-	PUNCT
admet-3065	176	11	based	base	VERB
admet-3065	176	12	lipid	lipid	NOUN
admet-3065	176	13	,	,	PUNCT
admet-3065	176	14	remains	remain	VERB
admet-3065	176	15	a	a	DET
admet-3065	176	16	cornerstone	cornerstone	NOUN
admet-3065	176	17	in	in	ADP
admet-3065	176	18	this	this	DET
admet-3065	176	19	category	category	NOUN
admet-3065	176	20	.	.	PUNCT
admet-3065	177	1	primary	primary	ADJ
admet-3065	177	2	,	,	PUNCT
admet-3065	177	3	secondary	secondary	ADJ
admet-3065	177	4	,	,	PUNCT
admet-3065	177	5	tertiary	tertiary	ADJ
admet-3065	177	6	amines	amine	NOUN
admet-3065	177	7	and	and	CCONJ
admet-3065	177	8	polyamines	polyamine	NOUN
admet-3065	177	9	amines	amine	NOUN
admet-3065	177	10	,	,	PUNCT
admet-3065	177	11	categorized	categorize	VERB
admet-3065	177	12	as	as	ADP
admet-3065	177	13	primary	primary	ADJ
admet-3065	177	14	,	,	PUNCT
admet-3065	177	15	secondary	secondary	ADJ
admet-3065	177	16	,	,	PUNCT
admet-3065	177	17	or	or	CCONJ
admet-3065	177	18	tertiary	tertiary	ADJ
admet-3065	177	19	based	base	VERB
admet-3065	177	20	on	on	ADP
admet-3065	177	21	the	the	DET
admet-3065	177	22	number	number	NOUN
admet-3065	177	23	of	of	ADP
admet-3065	177	24	organic	organic	ADJ
admet-3065	177	25	substituents	substituent	NOUN
admet-3065	177	26	on	on	ADP
admet-3065	177	27	the	the	DET
admet-3065	177	28	ammonia	ammonia	NOUN
admet-3065	177	29	molecule	molecule	NOUN
admet-3065	177	30	,	,	PUNCT
admet-3065	177	31	are	be	AUX
admet-3065	177	32	versatile	versatile	ADV
admet-3065	177	33	weak	weak	ADJ
admet-3065	177	34	bases	basis	NOUN
admet-3065	177	35	with	with	ADP
admet-3065	177	36	acid	acid	NOUN
admet-3065	177	37	-	-	PUNCT
admet-3065	177	38	base	base	NOUN
admet-3065	177	39	properties	property	NOUN
admet-3065	177	40	influenced	influence	VERB
admet-3065	177	41	by	by	ADP
admet-3065	177	42	substitution	substitution	NOUN
admet-3065	177	43	patterns	pattern	NOUN
admet-3065	177	44	.	.	PUNCT
admet-3065	178	1	secondary	secondary	ADJ
admet-3065	178	2	amines	amine	NOUN
admet-3065	178	3	(	(	PUNCT
admet-3065	178	4	pka	pka	PROPN
admet-3065	178	5			NOUN
admet-3065	178	6	10.8	10.8	NUM
admet-3065	178	7	)	)	PUNCT
admet-3065	178	8	are	be	AUX
admet-3065	178	9	slightly	slightly	ADV
admet-3065	178	10	more	more	ADV
admet-3065	178	11	basic	basic	ADJ
admet-3065	178	12	than	than	ADP
admet-3065	178	13	primary	primary	ADJ
admet-3065	178	14	amines	amine	NOUN
admet-3065	178	15	(	(	PUNCT
admet-3065	178	16	pka	pka	PROPN
admet-3065	178	17			NOUN
admet-3065	178	18	10.6	10.6	NUM
admet-3065	178	19	)	)	PUNCT
admet-3065	178	20	,	,	PUNCT
admet-3065	178	21	while	while	SCONJ
admet-3065	178	22	tertiary	tertiary	ADJ
admet-3065	178	23	amines	amine	NOUN
admet-3065	178	24	(	(	PUNCT
admet-3065	178	25	pka	pka	PROPN
admet-3065	178	26			NOUN
admet-3065	178	27	9.8	9.8	NUM
admet-3065	178	28	)	)	PUNCT
admet-3065	178	29	exhibit	exhibit	NOUN
admet-3065	178	30	reduced	reduce	VERB
admet-3065	178	31	basicity	basicity	NOUN
admet-3065	178	32	due	due	ADP
admet-3065	178	33	to	to	ADP
admet-3065	178	34	steric	steric	ADJ
admet-3065	178	35	hindrance	hindrance	NOUN
admet-3065	178	36	[	[	X
admet-3065	178	37	86	86	NUM
admet-3065	178	38	]	]	PUNCT
admet-3065	178	39	.	.	PUNCT
admet-3065	179	1	at	at	ADP
admet-3065	179	2	physiological	physiological	ADJ
admet-3065	179	3	ph	ph	VERB
admet-3065	179	4	,	,	PUNCT
admet-3065	179	5	amine	amine	ADJ
admet-3065	179	6	headgroups	headgroup	NOUN
admet-3065	179	7	are	be	AUX
admet-3065	179	8	typically	typically	ADV
admet-3065	179	9	neutral	neutral	ADJ
admet-3065	179	10	or	or	CCONJ
admet-3065	179	11	weakly	weakly	ADJ
admet-3065	179	12	cationic	cationic	ADJ
admet-3065	179	13	,	,	PUNCT
admet-3065	179	14	extending	extend	VERB
admet-3065	179	15	circulation	circulation	NOUN
admet-3065	179	16	half	half	NOUN
admet-3065	179	17	-	-	PUNCT
admet-3065	179	18	lives	life	NOUN
admet-3065	179	19	but	but	CCONJ
admet-3065	179	20	reducing	reduce	VERB
admet-3065	179	21	na	na	ADP
admet-3065	179	22	binding	bind	VERB
admet-3065	179	23	strength	strength	NOUN
admet-3065	179	24	compared	compare	VERB
admet-3065	179	25	to	to	ADP
admet-3065	179	26	quaternary	quaternary	ADJ
admet-3065	179	27	ammonium	ammonium	NOUN
admet-3065	179	28	groups	group	NOUN
admet-3065	179	29	[	[	X
admet-3065	179	30	87	87	NUM
admet-3065	179	31	]	]	PUNCT
admet-3065	179	32	.	.	PUNCT
admet-3065	180	1	the	the	DET
admet-3065	180	2	transfection	transfection	NOUN
admet-3065	180	3	efficacy	efficacy	NOUN
admet-3065	180	4	of	of	ADP
admet-3065	180	5	amine	amine	NOUN
admet-3065	180	6	-	-	PUNCT
admet-3065	180	7	based	base	VERB
admet-3065	180	8	lipids	lipid	NOUN
admet-3065	180	9	varies	vary	VERB
admet-3065	180	10	[	[	X
admet-3065	180	11	88	88	NUM
admet-3065	180	12	]	]	PUNCT
admet-3065	180	13	.	.	PUNCT
admet-3065	181	1	polyamine	polyamine	NOUN
admet-3065	181	2	-	-	PUNCT
admet-3065	181	3	containing	contain	VERB
admet-3065	181	4	lipids	lipid	NOUN
admet-3065	181	5	are	be	AUX
admet-3065	181	6	highly	highly	ADV
admet-3065	181	7	effective	effective	ADJ
admet-3065	181	8	for	for	ADP
admet-3065	181	9	gene	gene	NOUN
admet-3065	181	10	delivery	delivery	NOUN
admet-3065	181	11	.	.	PUNCT
admet-3065	182	1	for	for	ADP
admet-3065	182	2	instance	instance	NOUN
admet-3065	182	3	,	,	PUNCT
admet-3065	182	4	ctap	ctap	NOUN
admet-3065	182	5	,	,	PUNCT
admet-3065	182	6	a	a	DET
admet-3065	182	7	penta	penta	ADJ
admet-3065	182	8	-	-	PUNCT
admet-3065	182	9	amine	amine	NOUN
admet-3065	182	10	derivative	derivative	NOUN
admet-3065	182	11	,	,	PUNCT
admet-3065	182	12	demonstrated	demonstrate	VERB
admet-3065	182	13	100	100	NUM
admet-3065	182	14	-	-	ADJ
admet-3065	182	15	fold	fold	VERB
admet-3065	182	16	higher	high	ADJ
admet-3065	182	17	transfection	transfection	NOUN
admet-3065	182	18	efficiency	efficiency	NOUN
admet-3065	182	19	than	than	ADP
admet-3065	182	20	conventional	conventional	ADJ
admet-3065	182	21	dc	dc	PROPN
admet-3065	182	22	-	-	PUNCT
admet-3065	182	23	chol	chol	NOUN
admet-3065	182	24	/	/	SYM
admet-3065	182	25	dope	dope	NOUN
admet-3065	182	26	formulations	formulation	NOUN
admet-3065	182	27	due	due	ADP
admet-3065	182	28	to	to	ADP
admet-3065	182	29	the	the	DET
admet-3065	182	30	high	high	ADJ
admet-3065	182	31	charge	charge	NOUN
admet-3065	182	32	density	density	NOUN
admet-3065	182	33	of	of	ADP
admet-3065	182	34	fully	fully	ADV
admet-3065	182	35	protonated	protonate	VERB
admet-3065	182	36	polyamines	polyamine	NOUN
admet-3065	182	37	at	at	ADP
admet-3065	182	38	physiological	physiological	ADJ
admet-3065	182	39	ph	ph	NOUN
admet-3065	182	40	,	,	PUNCT
admet-3065	182	41	enabling	enable	VERB
admet-3065	182	42	efficient	efficient	ADJ
admet-3065	182	43	na	na	ADP
admet-3065	182	44	neutralization	neutralization	NOUN
admet-3065	182	45	and	and	CCONJ
admet-3065	182	46	condensation	condensation	NOUN
admet-3065	182	47	[	[	X
admet-3065	182	48	89	89	NUM
admet-3065	182	49	]	]	PUNCT
admet-3065	182	50	.	.	PUNCT
admet-3065	183	1	structural	structural	ADJ
admet-3065	183	2	configuration	configuration	NOUN
admet-3065	183	3	is	be	AUX
admet-3065	183	4	critical	critical	ADJ
admet-3065	183	5	,	,	PUNCT
admet-3065	183	6	with	with	ADP
admet-3065	183	7	linear	linear	ADJ
admet-3065	183	8	polyamines	polyamine	NOUN
admet-3065	183	9	outperforming	outperform	VERB
admet-3065	183	10	branched	branch	VERB
admet-3065	183	11	,	,	PUNCT
admet-3065	183	12	t	t	NOUN
admet-3065	183	13	-	-	PUNCT
admet-3065	183	14	shaped	shape	VERB
admet-3065	183	15	,	,	PUNCT
admet-3065	183	16	or	or	CCONJ
admet-3065	183	17	globular	globular	ADJ
admet-3065	183	18	variants	variant	NOUN
admet-3065	183	19	in	in	ADP
admet-3065	183	20	na	na	ADP
admet-3065	183	21	condensation	condensation	NOUN
admet-3065	183	22	and	and	CCONJ
admet-3065	183	23	transfection	transfection	NOUN
admet-3065	183	24	[	[	X
admet-3065	183	25	89	89	NUM
admet-3065	183	26	]	]	PUNCT
admet-3065	183	27	with	with	ADP
admet-3065	183	28	dogs	dog	NOUN
admet-3065	183	29	,	,	PUNCT
admet-3065	183	30	inspiring	inspiring	ADJ
admet-3065	183	31	spermine	spermine	NOUN
admet-3065	183	32	-	-	PUNCT
admet-3065	183	33	based	base	VERB
admet-3065	183	34	vector	vector	NOUN
admet-3065	183	35	designs	design	NOUN
admet-3065	183	36	[	[	X
admet-3065	183	37	87	87	NUM
admet-3065	183	38	]	]	PUNCT
admet-3065	183	39	.	.	PUNCT
admet-3065	184	1	although	although	SCONJ
admet-3065	184	2	branched	branched	ADJ
admet-3065	184	3	polyamines	polyamine	NOUN
admet-3065	184	4	offer	offer	VERB
admet-3065	184	5	conformational	conformational	ADJ
admet-3065	184	6	stability	stability	NOUN
admet-3065	184	7	[	[	X
admet-3065	184	8	90	90	NUM
admet-3065	184	9	]	]	PUNCT
admet-3065	184	10	,	,	PUNCT
admet-3065	184	11	their	their	PRON
admet-3065	184	12	transfection	transfection	NOUN
admet-3065	184	13	efficiency	efficiency	NOUN
admet-3065	184	14	is	be	AUX
admet-3065	184	15	generally	generally	ADV
admet-3065	184	16	lower	low	ADJ
admet-3065	184	17	than	than	ADP
admet-3065	184	18	that	that	PRON
admet-3065	184	19	of	of	ADP
admet-3065	184	20	linear	linear	ADJ
admet-3065	184	21	analogues	analogue	NOUN
admet-3065	184	22	[	[	X
admet-3065	184	23	90	90	NUM
admet-3065	184	24	]	]	PUNCT
admet-3065	184	25	.	.	PUNCT
admet-3065	185	1	guanidinium	guanidinium	PROPN
admet-3065	185	2	headgroup	headgroup	PROPN
admet-3065	185	3	guanidine	guanidine	PROPN
admet-3065	185	4	,	,	PUNCT
admet-3065	185	5	prevalent	prevalent	NOUN
admet-3065	185	6	in	in	ADP
admet-3065	185	7	arginine	arginine	NOUN
admet-3065	185	8	residues	residue	NOUN
admet-3065	185	9	of	of	ADP
admet-3065	185	10	dna	dna	NOUN
admet-3065	185	11	-	-	PUNCT
admet-3065	185	12	binding	bind	VERB
admet-3065	185	13	histones	histone	NOUN
admet-3065	185	14	,	,	PUNCT
admet-3065	185	15	exhibits	exhibit	VERB
admet-3065	185	16	strong	strong	ADJ
admet-3065	185	17	na	na	ADP
admet-3065	185	18	binding	bind	VERB
admet-3065	185	19	due	due	ADP
admet-3065	185	20	to	to	ADP
admet-3065	185	21	its	its	PRON
admet-3065	185	22	near	near	ADJ
admet-3065	185	23	-	-	PUNCT
admet-3065	185	24	complete	complete	ADJ
admet-3065	185	25	protonation	protonation	NOUN
admet-3065	185	26	to	to	ADP
admet-3065	185	27	guanidinium	guanidinium	NOUN
admet-3065	185	28	cations	cation	NOUN
admet-3065	185	29	across	across	ADP
admet-3065	185	30	a	a	DET
admet-3065	185	31	wide	wide	ADJ
admet-3065	185	32	ph	ph	ADJ
admet-3065	185	33	range	range	NOUN
admet-3065	185	34	,	,	PUNCT
admet-3065	185	35	facilitated	facilitate	VERB
admet-3065	185	36	by	by	ADP
admet-3065	185	37	charge	charge	NOUN
admet-3065	185	38	delocalization	delocalization	NOUN
admet-3065	185	39	across	across	ADP
admet-3065	185	40	three	three	NUM
admet-3065	185	41	nitrogen	nitrogen	NOUN
admet-3065	185	42	atoms	atom	NOUN
admet-3065	185	43	[	[	X
admet-3065	185	44	91,92	91,92	NUM
admet-3065	185	45	]	]	X
admet-3065	185	46	.	.	PUNCT
admet-3065	186	1	the	the	DET
admet-3065	186	2	guanidinium	guanidinium	NOUN
admet-3065	186	3	group	group	NOUN
admet-3065	186	4	supports	support	VERB
admet-3065	186	5	bidentate	bidentate	ADJ
admet-3065	186	6	hydrogen	hydrogen	NOUN
admet-3065	186	7	bonding	bonding	NOUN
admet-3065	186	8	with	with	ADP
admet-3065	186	9	anionic	anionic	ADJ
admet-3065	186	10	phospholipids	phospholipid	NOUN
admet-3065	186	11	in	in	ADP
admet-3065	186	12	cell	cell	NOUN
admet-3065	186	13	membranes	membrane	NOUN
admet-3065	186	14	,	,	PUNCT
admet-3065	186	15	enhancing	enhance	VERB
admet-3065	186	16	lipoplex	lipoplex	ADJ
admet-3065	186	17	internalization	internalization	NOUN
admet-3065	186	18	[	[	X
admet-3065	186	19	93	93	NUM
admet-3065	186	20	]	]	PUNCT
admet-3065	186	21	.	.	PUNCT
admet-3065	187	1	however	however	ADV
admet-3065	187	2	,	,	PUNCT
admet-3065	187	3	excessive	excessive	ADJ
admet-3065	187	4	binding	bind	VERB
admet-3065	187	5	affinity	affinity	NOUN
admet-3065	187	6	may	may	AUX
admet-3065	187	7	impede	impede	VERB
admet-3065	187	8	na	na	PART
admet-3065	187	9	release	release	VERB
admet-3065	187	10	,	,	PUNCT
admet-3065	187	11	potentially	potentially	ADV
admet-3065	187	12	reducing	reduce	VERB
admet-3065	187	13	gene	gene	NOUN
admet-3065	187	14	delivery	delivery	NOUN
admet-3065	187	15	efficiency	efficiency	NOUN
admet-3065	187	16	[	[	X
admet-3065	187	17	94,95	94,95	NOUN
admet-3065	187	18	]	]	X
admet-3065	187	19	.	.	PUNCT
admet-3065	188	1	multivalent	multivalent	NOUN
admet-3065	188	2	derivatives	derivative	NOUN
admet-3065	188	3	combining	combine	VERB
admet-3065	188	4	guanidinium	guanidinium	NOUN
admet-3065	188	5	with	with	ADP
admet-3065	188	6	pyridinium	pyridinium	NOUN
admet-3065	188	7	or	or	CCONJ
admet-3065	188	8	amine	amine	ADJ
admet-3065	188	9	groups	group	NOUN
admet-3065	188	10	have	have	AUX
admet-3065	188	11	since	since	SCONJ
admet-3065	188	12	improved	improve	VERB
admet-3065	188	13	transfection	transfection	NOUN
admet-3065	188	14	efficiency	efficiency	NOUN
admet-3065	188	15	and	and	CCONJ
admet-3065	188	16	reduced	reduce	VERB
admet-3065	188	17	cytotoxicity	cytotoxicity	NOUN
admet-3065	188	18	compared	compare	VERB
admet-3065	188	19	to	to	ADP
admet-3065	188	20	monovalent	monovalent	NOUN
admet-3065	188	21	counterparts	counterpart	NOUN
admet-3065	188	22	[	[	X
admet-3065	188	23	96	96	NUM
admet-3065	188	24	]	]	PUNCT
admet-3065	188	25	.	.	PUNCT
admet-3065	189	1	for	for	ADP
admet-3065	189	2	example	example	NOUN
admet-3065	189	3	,	,	PUNCT
admet-3065	189	4	dsgla	dsgla	PROPN
admet-3065	189	5	,	,	PUNCT
admet-3065	189	6	incorporating	incorporate	VERB
admet-3065	189	7	guanidinium	guanidinium	NOUN
admet-3065	189	8	and	and	CCONJ
admet-3065	189	9	lysine	lysine	NOUN
admet-3065	189	10	residues	residue	NOUN
admet-3065	189	11	,	,	PUNCT
admet-3065	189	12	showed	show	VERB
admet-3065	189	13	superior	superior	ADJ
admet-3065	189	14	sirna	sirna	PROPN
admet-3065	189	15	binding	bind	VERB
admet-3065	189	16	compared	compare	VERB
admet-3065	189	17	to	to	ADP
admet-3065	189	18	dotap	dotap	NOUN
admet-3065	189	19	[	[	X
admet-3065	189	20	97	97	NUM
admet-3065	189	21	]	]	PUNCT
admet-3065	189	22	.	.	PUNCT
admet-3065	190	1	amidine	amidine	PROPN
admet-3065	190	2	derivatives	derivative	NOUN
admet-3065	190	3	,	,	PUNCT
admet-3065	190	4	formed	form	VERB
admet-3065	190	5	by	by	ADP
admet-3065	190	6	substituting	substitute	VERB
admet-3065	190	7	a	a	DET
admet-3065	190	8	guanidine	guanidine	NOUN
admet-3065	190	9	amine	amine	NOUN
admet-3065	190	10	with	with	ADP
admet-3065	190	11	an	an	DET
admet-3065	190	12	r	r	NOUN
admet-3065	190	13	group	group	NOUN
admet-3065	190	14	,	,	PUNCT
admet-3065	190	15	offer	offer	VERB
admet-3065	190	16	tuneable	tuneable	ADJ
admet-3065	190	17	basicity	basicity	NOUN
admet-3065	190	18	(	(	PUNCT
admet-3065	190	19	pka	pka	NOUN
admet-3065	190	20	5	5	NUM
admet-3065	190	21	to	to	PART
admet-3065	190	22	12	12	NUM
admet-3065	190	23	)	)	PUNCT
admet-3065	190	24	and	and	CCONJ
admet-3065	190	25	consistent	consistent	ADJ
admet-3065	190	26	protonation	protonation	NOUN
admet-3065	190	27	at	at	ADP
admet-3065	190	28	the	the	DET
admet-3065	190	29	imino	imino	NOUN
admet-3065	190	30	nitrogen	nitrogen	NOUN
admet-3065	190	31	,	,	PUNCT
admet-3065	190	32	with	with	ADP
admet-3065	190	33	the	the	DET
admet-3065	190	34	trx	trx	PROPN
admet-3065	190	35	gemini	gemini	PROPN
admet-3065	190	36	surfactant	surfactant	NOUN
admet-3065	190	37	outperforming	outperforming	NOUN
admet-3065	190	38	lipofectamine	lipofectamine	NOUN
admet-3065	190	39	in	in	ADP
admet-3065	190	40	transfection	transfection	NOUN
admet-3065	190	41	efficiency	efficiency	NOUN
admet-3065	190	42	with	with	ADP
admet-3065	190	43	lower	low	ADJ
admet-3065	190	44	cytotoxicity	cytotoxicity	NOUN
admet-3065	190	45	[	[	X
admet-3065	190	46	98	98	NUM
admet-3065	190	47	]	]	PUNCT
admet-3065	190	48	.	.	PUNCT
admet-3065	191	1	e.	e.	PROPN
admet-3065	191	2	j.	j.	PROPN
admet-3065	191	3	saleh	saleh	PROPN
admet-3065	191	4	et	et	PROPN
admet-3065	191	5	al	al	PROPN
admet-3065	191	6	.	.	PROPN
admet-3065	191	7	admet	admet	PROPN
admet-3065	191	8	&	&	CCONJ
admet-3065	191	9	dmpk	dmpk	PROPN
admet-3065	191	10	00(0	00(0	PROPN
admet-3065	191	11	)	)	PUNCT
admet-3065	191	12	(	(	PUNCT
admet-3065	191	13	2025	2025	NUM
admet-3065	191	14	)	)	PUNCT
admet-3065	191	15	3065	3065	NUM
admet-3065	191	16	10	10	NUM
admet-3065	191	17	heterocyclic	heterocyclic	NOUN
admet-3065	191	18	headgroups	headgroup	NOUN
admet-3065	191	19	heterocyclic	heterocyclic	PROPN
admet-3065	191	20	compounds	compound	NOUN
admet-3065	191	21	,	,	PUNCT
admet-3065	191	22	such	such	ADJ
admet-3065	191	23	as	as	ADP
admet-3065	191	24	pyridine	pyridine	NOUN
admet-3065	191	25	and	and	CCONJ
admet-3065	191	26	imidazole	imidazole	NOUN
admet-3065	191	27	derivatives	derivative	NOUN
admet-3065	191	28	,	,	PUNCT
admet-3065	191	29	are	be	AUX
admet-3065	191	30	widely	widely	ADV
admet-3065	191	31	used	use	VERB
admet-3065	191	32	as	as	ADP
admet-3065	191	33	cationic	cationic	ADJ
admet-3065	191	34	headgroups	headgroup	NOUN
admet-3065	191	35	in	in	ADP
admet-3065	191	36	gene	gene	NOUN
admet-3065	191	37	delivery	delivery	NOUN
admet-3065	191	38	systems	system	NOUN
admet-3065	191	39	due	due	ADP
admet-3065	191	40	to	to	ADP
admet-3065	191	41	their	their	PRON
admet-3065	191	42	amphoteric	amphoteric	ADJ
admet-3065	191	43	properties	property	NOUN
admet-3065	191	44	.	.	PUNCT
admet-3065	192	1	imidazole	imidazole	NOUN
admet-3065	192	2	,	,	PUNCT
admet-3065	192	3	with	with	ADP
admet-3065	192	4	approximately	approximately	ADV
admet-3065	192	5	100	100	NUM
admet-3065	192	6	-	-	NUM
admet-3065	192	7	fold	fold	VERB
admet-3065	192	8	greater	great	ADJ
admet-3065	192	9	basicity	basicity	NOUN
admet-3065	192	10	than	than	ADP
admet-3065	192	11	pyridine	pyridine	NOUN
admet-3065	192	12	,	,	PUNCT
admet-3065	192	13	protonates	protonate	NOUN
admet-3065	192	14	in	in	ADP
admet-3065	192	15	acidic	acidic	ADJ
admet-3065	192	16	environments	environment	NOUN
admet-3065	192	17	to	to	PART
admet-3065	192	18	form	form	VERB
admet-3065	192	19	pyridinium	pyridinium	NOUN
admet-3065	192	20	or	or	CCONJ
admet-3065	192	21	imidazolium	imidazolium	NOUN
admet-3065	192	22	ions	ion	NOUN
admet-3065	192	23	with	with	ADP
admet-3065	192	24	delocalized	delocalize	VERB
admet-3065	192	25	positive	positive	ADJ
admet-3065	192	26	charges	charge	NOUN
admet-3065	192	27	,	,	PUNCT
admet-3065	192	28	optimizing	optimize	VERB
admet-3065	192	29	na	na	ADP
admet-3065	192	30	binding	bind	VERB
admet-3065	192	31	-	-	PUNCT
admet-3065	192	32	release	release	NOUN
admet-3065	192	33	dynamics	dynamic	NOUN
admet-3065	192	34	through	through	ADP
admet-3065	192	35	ph	ph	ADJ
admet-3065	192	36	-	-	ADJ
admet-3065	192	37	sensitive	sensitive	ADJ
admet-3065	192	38	behaviour	behaviour	NOUN
admet-3065	193	1	[	[	X
admet-3065	193	2	99,100	99,100	NUM
admet-3065	193	3	]	]	PUNCT
admet-3065	193	4	.	.	PUNCT
admet-3065	194	1	cyclen	cyclen	NOUN
admet-3065	194	2	-	-	PUNCT
admet-3065	194	3	based	base	VERB
admet-3065	194	4	lipids	lipid	NOUN
admet-3065	194	5	with	with	ADP
admet-3065	194	6	imidazole	imidazole	NOUN
admet-3065	194	7	headgroups	headgroup	NOUN
admet-3065	194	8	(	(	PUNCT
admet-3065	194	9	pka	pka	PROPN
admet-3065	194	10			NOUN
admet-3065	194	11	6.0	6.0	NUM
admet-3065	194	12	)	)	PUNCT
admet-3065	194	13	[	[	X
admet-3065	194	14	99	99	NUM
admet-3065	194	15	]	]	PUNCT
admet-3065	194	16	align	align	NOUN
admet-3065	194	17	with	with	ADP
admet-3065	194	18	endosomal	endosomal	ADJ
admet-3065	194	19	ph	ph	VERB
admet-3065	194	20	,	,	PUNCT
admet-3065	194	21	promoting	promote	VERB
admet-3065	194	22	efficient	efficient	ADJ
admet-3065	194	23	transfection	transfection	NOUN
admet-3065	194	24	via	via	ADP
admet-3065	194	25	the	the	DET
admet-3065	194	26	proton	proton	NOUN
admet-3065	194	27	sponge	sponge	NOUN
admet-3065	194	28	effect	effect	NOUN
admet-3065	194	29	[	[	X
admet-3065	194	30	82	82	NUM
admet-3065	194	31	]	]	PUNCT
admet-3065	194	32	.	.	PUNCT
admet-3065	195	1	body	body	NOUN
admet-3065	195	2	(	(	PUNCT
admet-3065	195	3	linker	linker	NOUN
admet-3065	195	4	)	)	PUNCT
admet-3065	195	5	in	in	ADP
admet-3065	195	6	cationic	cationic	ADJ
admet-3065	195	7	lipids	lipid	NOUN
admet-3065	195	8	,	,	PUNCT
admet-3065	195	9	the	the	DET
admet-3065	195	10	linker	linker	NOUN
admet-3065	195	11	moiety	moiety	NOUN
admet-3065	195	12	serves	serve	VERB
admet-3065	195	13	as	as	ADP
admet-3065	195	14	a	a	DET
admet-3065	195	15	critical	critical	ADJ
admet-3065	195	16	structural	structural	ADJ
admet-3065	195	17	bridge	bridge	NOUN
admet-3065	195	18	connecting	connect	VERB
admet-3065	195	19	the	the	DET
admet-3065	195	20	hydrophilic	hydrophilic	ADJ
admet-3065	195	21	headgroup	headgroup	NOUN
admet-3065	195	22	to	to	ADP
admet-3065	195	23	the	the	DET
admet-3065	195	24	hydrophobic	hydrophobic	NOUN
admet-3065	195	25	tails	tail	NOUN
admet-3065	195	26	,	,	PUNCT
admet-3065	195	27	significantly	significantly	ADV
admet-3065	195	28	influencing	influence	VERB
admet-3065	195	29	the	the	DET
admet-3065	195	30	physicochemical	physicochemical	ADJ
admet-3065	195	31	properties	property	NOUN
admet-3065	195	32	and	and	CCONJ
admet-3065	195	33	biological	biological	ADJ
admet-3065	195	34	performance	performance	NOUN
admet-3065	195	35	of	of	ADP
admet-3065	195	36	lipoplexes	lipoplexe	NOUN
admet-3065	195	37	.	.	PUNCT
admet-3065	196	1	this	this	DET
admet-3065	196	2	linkage	linkage	NOUN
admet-3065	196	3	governs	govern	VERB
admet-3065	196	4	molecular	molecular	ADJ
admet-3065	196	5	stability	stability	NOUN
admet-3065	196	6	,	,	PUNCT
admet-3065	196	7	biodegradability	biodegradability	NOUN
admet-3065	196	8	,	,	PUNCT
admet-3065	196	9	cytotoxicity	cytotoxicity	NOUN
admet-3065	196	10	,	,	PUNCT
admet-3065	196	11	and	and	CCONJ
admet-3065	196	12	transfection	transfection	NOUN
admet-3065	196	13	efficiency	efficiency	NOUN
admet-3065	196	14	[	[	X
admet-3065	196	15	101	101	NUM
admet-3065	196	16	]	]	PUNCT
admet-3065	196	17	.	.	PUNCT
admet-3065	197	1	the	the	DET
admet-3065	197	2	linker	linker	NOUN
admet-3065	197	3	’s	’s	PART
admet-3065	197	4	chemical	chemical	ADJ
admet-3065	197	5	properties	property	NOUN
admet-3065	197	6	-	-	PUNCT
admet-3065	197	7	such	such	ADJ
admet-3065	197	8	as	as	ADP
admet-3065	197	9	charge	charge	NOUN
admet-3065	197	10	distribution	distribution	NOUN
admet-3065	197	11	,	,	PUNCT
admet-3065	197	12	length	length	NOUN
admet-3065	197	13	,	,	PUNCT
admet-3065	197	14	and	and	CCONJ
admet-3065	197	15	steric	steric	ADJ
admet-3065	197	16	constraintsmodulate	constraintsmodulate	VERB
admet-3065	197	17	the	the	DET
admet-3065	197	18	conformational	conformational	ADJ
admet-3065	197	19	flexibility	flexibility	NOUN
admet-3065	197	20	of	of	ADP
admet-3065	197	21	the	the	DET
admet-3065	197	22	amphiphile	amphiphile	NOUN
admet-3065	197	23	,	,	PUNCT
admet-3065	197	24	thereby	thereby	ADV
admet-3065	197	25	affecting	affect	VERB
admet-3065	197	26	the	the	DET
admet-3065	197	27	spatial	spatial	ADJ
admet-3065	197	28	arrangement	arrangement	NOUN
admet-3065	197	29	of	of	ADP
admet-3065	197	30	functional	functional	ADJ
admet-3065	197	31	groups	group	NOUN
admet-3065	197	32	,	,	PUNCT
admet-3065	197	33	nucleic	nucleic	ADJ
admet-3065	197	34	acid	acid	NOUN
admet-3065	197	35	(	(	PUNCT
admet-3065	197	36	na	na	NOUN
admet-3065	197	37	)	)	PUNCT
admet-3065	197	38	binding	bind	VERB
admet-3065	197	39	affinity	affinity	NOUN
admet-3065	197	40	,	,	PUNCT
admet-3065	197	41	and	and	CCONJ
admet-3065	197	42	overall	overall	ADJ
admet-3065	197	43	gene	gene	NOUN
admet-3065	197	44	delivery	delivery	NOUN
admet-3065	197	45	efficacy	efficacy	NOUN
admet-3065	197	46	[	[	X
admet-3065	197	47	102	102	NUM
admet-3065	197	48	]	]	PUNCT
admet-3065	197	49	.	.	PUNCT
admet-3065	198	1	linkers	linker	NOUN
admet-3065	198	2	are	be	AUX
admet-3065	198	3	typically	typically	ADV
admet-3065	198	4	classified	classify	VERB
admet-3065	198	5	by	by	ADP
admet-3065	198	6	their	their	PRON
admet-3065	198	7	core	core	ADJ
admet-3065	198	8	chemical	chemical	NOUN
admet-3065	198	9	structures	structure	NOUN
admet-3065	198	10	,	,	PUNCT
admet-3065	198	11	with	with	ADP
admet-3065	198	12	common	common	ADJ
admet-3065	198	13	types	type	NOUN
admet-3065	198	14	including	include	VERB
admet-3065	198	15	ether	ether	NOUN
admet-3065	198	16	,	,	PUNCT
admet-3065	198	17	ester	ester	NOUN
admet-3065	198	18	,	,	PUNCT
admet-3065	198	19	carbamate	carbamate	NOUN
admet-3065	198	20	,	,	PUNCT
admet-3065	198	21	and	and	CCONJ
admet-3065	198	22	amide	amide	NOUN
admet-3065	198	23	bonds	bond	NOUN
admet-3065	198	24	(	(	PUNCT
admet-3065	198	25	table	table	NOUN
admet-3065	198	26	4	4	NUM
admet-3065	198	27	)	)	PUNCT
admet-3065	198	28	.	.	PUNCT
admet-3065	199	1	recent	recent	ADJ
admet-3065	199	2	advancements	advancement	NOUN
admet-3065	199	3	have	have	AUX
admet-3065	199	4	focused	focus	VERB
admet-3065	199	5	on	on	ADP
admet-3065	199	6	designing	design	VERB
admet-3065	199	7	stimulus	stimulus	NOUN
admet-3065	199	8	-	-	PUNCT
admet-3065	199	9	responsive	responsive	ADJ
admet-3065	199	10	linkers	linker	NOUN
admet-3065	199	11	that	that	PRON
admet-3065	199	12	undergo	undergo	VERB
admet-3065	199	13	controlled	control	VERB
admet-3065	199	14	structural	structural	ADJ
admet-3065	199	15	changes	change	NOUN
admet-3065	199	16	in	in	ADP
admet-3065	199	17	response	response	NOUN
admet-3065	199	18	to	to	ADP
admet-3065	199	19	environmental	environmental	ADJ
admet-3065	199	20	cues	cue	NOUN
admet-3065	199	21	,	,	PUNCT
admet-3065	199	22	such	such	ADJ
admet-3065	199	23	as	as	ADP
admet-3065	199	24	ph	ph	ADJ
admet-3065	199	25	variations	variation	NOUN
admet-3065	199	26	,	,	PUNCT
admet-3065	199	27	redox	redox	ADJ
admet-3065	199	28	potential	potential	NOUN
admet-3065	199	29	,	,	PUNCT
admet-3065	199	30	or	or	CCONJ
admet-3065	199	31	enzymatic	enzymatic	ADJ
admet-3065	199	32	activity	activity	NOUN
admet-3065	199	33	[	[	X
admet-3065	199	34	103	103	NUM
admet-3065	199	35	]	]	PUNCT
admet-3065	199	36	.	.	PUNCT
admet-3065	200	1	the	the	DET
admet-3065	200	2	following	follow	VERB
admet-3065	200	3	sections	section	NOUN
admet-3065	200	4	detail	detail	VERB
admet-3065	200	5	key	key	ADJ
admet-3065	200	6	developments	development	NOUN
admet-3065	200	7	in	in	ADP
admet-3065	200	8	linker	linker	NOUN
admet-3065	200	9	design	design	NOUN
admet-3065	200	10	and	and	CCONJ
admet-3065	200	11	their	their	PRON
admet-3065	200	12	impact	impact	NOUN
admet-3065	200	13	on	on	ADP
admet-3065	200	14	gene	gene	NOUN
admet-3065	200	15	delivery	delivery	NOUN
admet-3065	200	16	applications	application	NOUN
admet-3065	200	17	.	.	PUNCT
admet-3065	201	1	table	table	NOUN
admet-3065	201	2	4	4	NUM
admet-3065	201	3	.	.	PUNCT
admet-3065	202	1	overview	overview	NOUN
admet-3065	202	2	of	of	ADP
admet-3065	202	3	linker	linker	NOUN
admet-3065	202	4	types	type	NOUN
admet-3065	202	5	and	and	CCONJ
admet-3065	202	6	their	their	PRON
admet-3065	202	7	roles	role	NOUN
admet-3065	202	8	in	in	ADP
admet-3065	202	9	cationic	cationic	ADJ
admet-3065	202	10	lipid	lipid	NOUN
admet-3065	202	11	design	design	NOUN
admet-3065	202	12	.	.	PUNCT
admet-3065	203	1	linker	linker	NOUN
admet-3065	203	2	type	type	NOUN
admet-3065	203	3	example	example	NOUN
admet-3065	203	4	lipids	lipid	VERB
admet-3065	203	5	properties	property	NOUN
admet-3065	203	6	biodegradability	biodegradability	NOUN
admet-3065	203	7	role	role	NOUN
admet-3065	203	8	in	in	ADP
admet-3065	203	9	gene	gene	NOUN
admet-3065	203	10	delivery	delivery	NOUN
admet-3065	203	11	ether	ether	NOUN
admet-3065	203	12	dotma	dotma	NOUN
admet-3065	203	13	chemically	chemically	ADV
admet-3065	203	14	stable	stable	ADJ
admet-3065	203	15	poor	poor	ADJ
admet-3065	203	16	high	high	ADJ
admet-3065	203	17	transfection	transfection	NOUN
admet-3065	203	18	,	,	PUNCT
admet-3065	203	19	low	low	ADJ
admet-3065	203	20	degradability	degradability	NOUN
admet-3065	203	21	ester	ester	NOUN
admet-3065	203	22	dotap	dotap	NOUN
admet-3065	203	23	acid-/enzyme	acid-/enzyme	NOUN
admet-3065	203	24	-	-	PUNCT
admet-3065	203	25	labile	labile	ADJ
admet-3065	203	26	good	good	ADJ
admet-3065	203	27	biodegradable	biodegradable	ADJ
admet-3065	203	28	carbamate	carbamate	PROPN
admet-3065	203	29	dc	dc	PROPN
admet-3065	203	30	-	-	PUNCT
admet-3065	203	31	chol	chol	NOUN
admet-3065	203	32	ph	ph	VERB
admet-3065	203	33	-	-	ADJ
admet-3065	203	34	sensitive	sensitive	ADJ
admet-3065	203	35	good	good	ADJ
admet-3065	203	36	efficient	efficient	ADJ
admet-3065	203	37	and	and	CCONJ
admet-3065	203	38	low	low	ADJ
admet-3065	203	39	toxicity	toxicity	NOUN
admet-3065	203	40	amide	amide	NOUN
admet-3065	203	41	dogs	dog	NOUN
admet-3065	203	42	acid	acid	NOUN
admet-3065	203	43	-	-	PUNCT
admet-3065	203	44	labile	labile	NOUN
admet-3065	203	45	moderate	moderate	ADJ
admet-3065	203	46	stable	stable	ADJ
admet-3065	203	47	,	,	PUNCT
admet-3065	203	48	long	long	ADJ
admet-3065	203	49	-	-	PUNCT
admet-3065	203	50	term	term	NOUN
admet-3065	203	51	transfection	transfection	NOUN
admet-3065	203	52	disulfide	disulfide	NOUN
admet-3065	203	53	dogsdso	dogsdso	NOUN
admet-3065	203	54	redox	redox	NOUN
admet-3065	203	55	-	-	PUNCT
admet-3065	203	56	sensitive	sensitive	ADJ
admet-3065	203	57	high	high	PROPN
admet-3065	203	58	controlled	control	VERB
admet-3065	203	59	na	na	PART
admet-3065	203	60	release	release	VERB
admet-3065	203	61	miscellaneous	miscellaneous	ADJ
admet-3065	203	62	hydrazone	hydrazone	NOUN
admet-3065	203	63	,	,	PUNCT
admet-3065	203	64	ketal	ketal	ADJ
admet-3065	203	65	stimuli	stimulus	NOUN
admet-3065	203	66	-	-	PUNCT
admet-3065	203	67	sensitive	sensitive	ADJ
admet-3065	203	68	variable	variable	NOUN
admet-3065	203	69	stimuli	stimulus	NOUN
admet-3065	203	70	-	-	PUNCT
admet-3065	203	71	triggered	trigger	VERB
admet-3065	203	72	release	release	NOUN
admet-3065	203	73	ethers	ether	NOUN
admet-3065	203	74	ether	ether	NOUN
admet-3065	203	75	linkages	linkage	NOUN
admet-3065	203	76	,	,	PUNCT
admet-3065	203	77	characterized	characterize	VERB
admet-3065	203	78	by	by	ADP
admet-3065	203	79	an	an	DET
admet-3065	203	80	oxygen	oxygen	NOUN
admet-3065	203	81	atom	atom	NOUN
admet-3065	203	82	bridging	bridging	NOUN
admet-3065	203	83	two	two	NUM
admet-3065	203	84	alkyl	alkyl	ADJ
admet-3065	203	85	groups	group	NOUN
admet-3065	203	86	(	(	PUNCT
admet-3065	203	87	figure	figure	NOUN
admet-3065	203	88	3a	3a	NUM
admet-3065	203	89	)	)	PUNCT
admet-3065	203	90	,	,	PUNCT
admet-3065	203	91	confer	confer	VERB
admet-3065	203	92	high	high	ADJ
admet-3065	203	93	stability	stability	NOUN
admet-3065	203	94	to	to	AUX
admet-3065	203	95	cationic	cationic	VERB
admet-3065	203	96	lipids	lipid	NOUN
admet-3065	203	97	but	but	CCONJ
admet-3065	203	98	pose	pose	VERB
admet-3065	203	99	challenges	challenge	NOUN
admet-3065	203	100	for	for	ADP
admet-3065	203	101	biodegradability	biodegradability	NOUN
admet-3065	203	102	.	.	PUNCT
admet-3065	204	1	comparative	comparative	ADJ
admet-3065	204	2	studies	study	NOUN
admet-3065	204	3	demonstrate	demonstrate	VERB
admet-3065	204	4	that	that	SCONJ
admet-3065	204	5	ether	ether	NOUN
admet-3065	204	6	-	-	PUNCT
admet-3065	204	7	linked	link	VERB
admet-3065	204	8	lipids	lipid	NOUN
admet-3065	204	9	,	,	PUNCT
admet-3065	204	10	such	such	ADJ
admet-3065	204	11	as	as	ADP
admet-3065	204	12	dotma	dotma	NOUN
admet-3065	204	13	,	,	PUNCT
admet-3065	204	14	exhibit	exhibit	VERB
admet-3065	204	15	up	up	ADP
admet-3065	204	16	to	to	PART
admet-3065	204	17	10	10	NUM
admet-3065	204	18	-	-	ADJ
admet-3065	204	19	fold	fold	VERB
admet-3065	204	20	higher	high	ADJ
admet-3065	204	21	transfection	transfection	NOUN
admet-3065	204	22	activity	activity	NOUN
admet-3065	204	23	than	than	ADP
admet-3065	204	24	ester	ester	NOUN
admet-3065	204	25	-	-	PUNCT
admet-3065	204	26	linked	link	VERB
admet-3065	204	27	lipids	lipid	NOUN
admet-3065	204	28	,	,	PUNCT
admet-3065	204	29	such	such	ADJ
admet-3065	204	30	as	as	ADP
admet-3065	204	31	dotap	dotap	NOUN
admet-3065	204	32	,	,	PUNCT
admet-3065	204	33	in	in	ADP
admet-3065	204	34	the	the	DET
admet-3065	204	35	absence	absence	NOUN
admet-3065	204	36	of	of	ADP
admet-3065	204	37	helper	helper	NOUN
admet-3065	204	38	lipids	lipids	ADP
admet-3065	204	39	[	[	X
admet-3065	204	40	103	103	NUM
admet-3065	204	41	]	]	PUNCT
admet-3065	204	42	.	.	PUNCT
admet-3065	205	1	other	other	ADJ
admet-3065	205	2	ether	ether	NOUN
admet-3065	205	3	-	-	PUNCT
admet-3065	205	4	containing	contain	VERB
admet-3065	205	5	formulations	formulation	NOUN
admet-3065	205	6	similarly	similarly	ADV
admet-3065	205	7	outperform	outperform	VERB
admet-3065	205	8	esterand	esterand	CCONJ
admet-3065	205	9	carbamate	carbamate	NOUN
admet-3065	205	10	-	-	PUNCT
admet-3065	205	11	based	base	VERB
admet-3065	205	12	lipids	lipid	NOUN
admet-3065	205	13	in	in	ADP
admet-3065	205	14	gene	gene	NOUN
admet-3065	205	15	delivery	delivery	NOUN
admet-3065	205	16	[	[	X
admet-3065	205	17	104	104	NUM
admet-3065	205	18	]	]	PUNCT
admet-3065	205	19	.	.	PUNCT
admet-3065	206	1	however	however	ADV
admet-3065	206	2	,	,	PUNCT
admet-3065	206	3	the	the	DET
admet-3065	206	4	chemical	chemical	ADJ
admet-3065	206	5	stability	stability	NOUN
admet-3065	206	6	of	of	ADP
admet-3065	206	7	ether	ether	ADJ
admet-3065	206	8	bonds	bond	NOUN
admet-3065	206	9	,	,	PUNCT
admet-3065	206	10	which	which	PRON
admet-3065	206	11	requires	require	VERB
admet-3065	206	12	harsh	harsh	ADJ
admet-3065	206	13	conditions	condition	NOUN
admet-3065	206	14	for	for	ADP
admet-3065	206	15	cleavage	cleavage	NOUN
admet-3065	206	16	,	,	PUNCT
admet-3065	206	17	limits	limit	VERB
admet-3065	206	18	their	their	PRON
admet-3065	206	19	metabolic	metabolic	NOUN
admet-3065	206	20	degradation	degradation	NOUN
admet-3065	206	21	and	and	CCONJ
admet-3065	206	22	may	may	AUX
admet-3065	206	23	increase	increase	VERB
admet-3065	206	24	cytotoxicity	cytotoxicity	NOUN
admet-3065	206	25	risks	risk	NOUN
admet-3065	206	26	[	[	X
admet-3065	206	27	105	105	NUM
admet-3065	206	28	]	]	PUNCT
admet-3065	206	29	.	.	PUNCT
admet-3065	207	1	esters	ester	NOUN
admet-3065	207	2	ester	ester	NOUN
admet-3065	207	3	linkages	linkage	NOUN
admet-3065	207	4	,	,	PUNCT
admet-3065	207	5	formed	form	VERB
admet-3065	207	6	by	by	ADP
admet-3065	207	7	substituting	substitute	VERB
admet-3065	207	8	the	the	DET
admet-3065	207	9	hydroxyl	hydroxyl	NOUN
admet-3065	207	10	group	group	NOUN
admet-3065	207	11	of	of	ADP
admet-3065	207	12	a	a	DET
admet-3065	207	13	carboxylic	carboxylic	ADJ
admet-3065	207	14	acid	acid	NOUN
admet-3065	207	15	with	with	ADP
admet-3065	207	16	an	an	DET
admet-3065	207	17	o	o	NOUN
admet-3065	207	18	-	-	NOUN
admet-3065	207	19	alkyl	alkyl	ADJ
admet-3065	207	20	(	(	PUNCT
admet-3065	207	21	alkoxy	alkoxy	ADJ
admet-3065	207	22	)	)	PUNCT
admet-3065	207	23	group	group	NOUN
admet-3065	207	24	(	(	PUNCT
admet-3065	207	25	figure	figure	NOUN
admet-3065	207	26	3b	3b	NUM
admet-3065	207	27	)	)	PUNCT
admet-3065	207	28	,	,	PUNCT
admet-3065	207	29	are	be	AUX
admet-3065	207	30	highly	highly	ADV
admet-3065	207	31	water	water	NOUN
admet-3065	207	32	-	-	PUNCT
admet-3065	207	33	soluble	soluble	ADJ
admet-3065	207	34	due	due	ADP
admet-3065	207	35	to	to	ADP
admet-3065	207	36	their	their	PRON
admet-3065	207	37	hydrogen	hydrogen	NOUN
admet-3065	207	38	bond	bond	NOUN
admet-3065	207	39	acceptor	acceptor	NOUN
admet-3065	207	40	properties	property	NOUN
admet-3065	207	41	.	.	PUNCT
admet-3065	208	1	these	these	DET
admet-3065	208	2	bonds	bond	NOUN
admet-3065	208	3	are	be	AUX
admet-3065	208	4	susceptible	susceptible	ADJ
admet-3065	208	5	to	to	ADP
admet-3065	208	6	acid	acid	NOUN
admet-3065	208	7	-	-	PUNCT
admet-3065	208	8	catalyzed	catalyze	VERB
admet-3065	208	9	hydrolysis	hydrolysis	NOUN
admet-3065	208	10	in	in	ADP
admet-3065	208	11	acidic	acidic	ADJ
admet-3065	208	12	intracellular	intracellular	ADJ
admet-3065	208	13	environments	environment	NOUN
admet-3065	208	14	and	and	CCONJ
admet-3065	208	15	enzymatic	enzymatic	ADJ
admet-3065	208	16	cleavage	cleavage	NOUN
admet-3065	208	17	by	by	ADP
admet-3065	208	18	endogenous	endogenous	ADJ
admet-3065	208	19	esterases	esterase	NOUN
admet-3065	208	20	or	or	CCONJ
admet-3065	208	21	lipases	lipase	NOUN
admet-3065	208	22	,	,	PUNCT
admet-3065	208	23	rendering	render	VERB
admet-3065	208	24	them	they	PRON
admet-3065	208	25	readily	readily	ADV
admet-3065	208	26	biodegradable	biodegradable	ADJ
admet-3065	208	27	[	[	X
admet-3065	208	28	29	29	NUM
admet-3065	208	29	]	]	PUNCT
admet-3065	208	30	.	.	PUNCT
admet-3065	209	1	dotap	dotap	PROPN
admet-3065	209	2	,	,	PUNCT
admet-3065	209	3	an	an	DET
admet-3065	209	4	early	early	ADJ
admet-3065	209	5	ester	ester	NOUN
admet-3065	209	6	-	-	PUNCT
admet-3065	209	7	containing	contain	VERB
admet-3065	209	8	cationic	cationic	ADJ
admet-3065	209	9	lipid	lipid	NOUN
admet-3065	209	10	(	(	PUNCT
admet-3065	209	11	figure	figure	NOUN
admet-3065	209	12	3b	3b	NUM
admet-3065	209	13	)	)	PUNCT
admet-3065	209	14	,	,	PUNCT
admet-3065	209	15	demonstrated	demonstrate	VERB
admet-3065	209	16	high	high	ADJ
admet-3065	209	17	transfection	transfection	NOUN
admet-3065	209	18	activity	activity	NOUN
admet-3065	210	1	[	[	X
admet-3065	210	2	106	106	NUM
admet-3065	210	3	]	]	PUNCT
admet-3065	210	4	,	,	PUNCT
admet-3065	210	5	leading	lead	VERB
admet-3065	210	6	to	to	ADP
admet-3065	210	7	its	its	PRON
admet-3065	210	8	use	use	NOUN
admet-3065	210	9	in	in	ADP
admet-3065	210	10	preclinical	preclinical	ADJ
admet-3065	210	11	and	and	CCONJ
admet-3065	210	12	clinical	clinical	ADJ
admet-3065	210	13	lipoplex	lipoplex	NOUN
admet-3065	210	14	formulations	formulation	NOUN
admet-3065	210	15	[	[	X
admet-3065	210	16	107	107	NUM
admet-3065	210	17	]	]	PUNCT
admet-3065	210	18	.	.	PUNCT
admet-3065	211	1	however	however	ADV
admet-3065	211	2	,	,	PUNCT
admet-3065	211	3	the	the	DET
admet-3065	211	4	chemical	chemical	NOUN
admet-3065	211	5	instability	instability	NOUN
admet-3065	211	6	of	of	ADP
admet-3065	211	7	ester	ester	NOUN
admet-3065	211	8	bonds	bond	NOUN
admet-3065	211	9	can	can	AUX
admet-3065	211	10	reduce	reduce	VERB
admet-3065	211	11	delivery	delivery	NOUN
admet-3065	211	12	efficiency	efficiency	NOUN
admet-3065	211	13	[	[	X
admet-3065	211	14	65	65	NUM
admet-3065	211	15	]	]	PUNCT
admet-3065	211	16	.	.	PUNCT
admet-3065	212	1	admet	admet	PROPN
admet-3065	212	2	&	&	CCONJ
admet-3065	212	3	dmpk	dmpk	PROPN
admet-3065	212	4	00(0	00(0	PROPN
admet-3065	212	5	)	)	PUNCT
admet-3065	212	6	(	(	PUNCT
admet-3065	212	7	2025	2025	NUM
admet-3065	212	8	)	)	PUNCT
admet-3065	212	9	3065	3065	NUM
admet-3065	212	10	liposome	liposome	NOUN
admet-3065	212	11	-	-	PUNCT
admet-3065	212	12	mediated	mediate	VERB
admet-3065	212	13	gene	gene	NOUN
admet-3065	212	14	delivery	delivery	NOUN
admet-3065	212	15	doi	doi	NOUN
admet-3065	212	16	:	:	PUNCT
admet-3065	212	17	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	212	18	11	11	NUM
admet-3065	212	19	carbamates	carbamate	NOUN
admet-3065	212	20	carbamate	carbamate	VERB
admet-3065	212	21	(	(	PUNCT
admet-3065	212	22	urethane	urethane	NOUN
admet-3065	212	23	)	)	PUNCT
admet-3065	212	24	linkers	linker	NOUN
admet-3065	212	25	provide	provide	VERB
admet-3065	212	26	greater	great	ADJ
admet-3065	212	27	stability	stability	NOUN
admet-3065	212	28	than	than	ADP
admet-3065	212	29	simple	simple	ADJ
admet-3065	212	30	esters	ester	NOUN
admet-3065	212	31	,	,	PUNCT
admet-3065	212	32	resulting	result	VERB
admet-3065	212	33	in	in	ADP
admet-3065	212	34	lipoplexes	lipoplexe	NOUN
admet-3065	212	35	with	with	ADP
admet-3065	212	36	excellent	excellent	ADJ
admet-3065	212	37	transfection	transfection	NOUN
admet-3065	212	38	efficiency	efficiency	NOUN
admet-3065	212	39	and	and	CCONJ
admet-3065	212	40	low	low	ADJ
admet-3065	212	41	cytotoxicity	cytotoxicity	NOUN
admet-3065	212	42	[	[	X
admet-3065	212	43	108	108	NUM
admet-3065	212	44	]	]	PUNCT
admet-3065	212	45	.	.	PUNCT
admet-3065	213	1	dc	dc	PROPN
admet-3065	213	2	-	-	PUNCT
admet-3065	213	3	chol	chol	PROPN
admet-3065	213	4	,	,	PUNCT
admet-3065	213	5	a	a	DET
admet-3065	213	6	representative	representative	ADJ
admet-3065	213	7	carbamate	carbamate	NOUN
admet-3065	213	8	-	-	PUNCT
admet-3065	213	9	containing	contain	VERB
admet-3065	213	10	cationic	cationic	ADJ
admet-3065	213	11	lipid	lipid	NOUN
admet-3065	213	12	(	(	PUNCT
admet-3065	213	13	figure	figure	NOUN
admet-3065	213	14	3c	3c	NUM
admet-3065	213	15	)	)	PUNCT
admet-3065	213	16	,	,	PUNCT
admet-3065	213	17	exemplifies	exemplify	VERB
admet-3065	213	18	these	these	DET
admet-3065	213	19	properties	property	NOUN
admet-3065	213	20	.	.	PUNCT
admet-3065	214	1	carbamate	carbamate	PROPN
admet-3065	214	2	linkers	linker	NOUN
admet-3065	214	3	are	be	AUX
admet-3065	214	4	hydrolysed	hydrolyse	VERB
admet-3065	214	5	in	in	ADP
admet-3065	214	6	the	the	DET
admet-3065	214	7	acidic	acidic	ADJ
admet-3065	214	8	endosomal	endosomal	ADJ
admet-3065	214	9	compartment	compartment	NOUN
admet-3065	214	10	and	and	CCONJ
admet-3065	214	11	cleaved	cleave	VERB
admet-3065	214	12	by	by	ADP
admet-3065	214	13	intracellular	intracellular	ADJ
admet-3065	214	14	esterases	esterase	NOUN
admet-3065	214	15	,	,	PUNCT
admet-3065	214	16	ensuring	ensure	VERB
admet-3065	214	17	biodegradability	biodegradability	NOUN
admet-3065	214	18	[	[	X
admet-3065	214	19	109	109	NUM
admet-3065	214	20	]	]	PUNCT
admet-3065	214	21	.	.	PUNCT
admet-3065	215	1	carbamatecontaining	carbamatecontaine	VERB
admet-3065	215	2	lipids	lipids	ADP
admet-3065	215	3	outperformed	outperform	VERB
admet-3065	215	4	etherand	etherand	NOUN
admet-3065	215	5	ester	ester	NOUN
admet-3065	215	6	-	-	PUNCT
admet-3065	215	7	based	base	VERB
admet-3065	215	8	analogues	analogue	NOUN
admet-3065	215	9	,	,	PUNCT
admet-3065	215	10	as	as	ADV
admet-3065	215	11	well	well	ADV
admet-3065	215	12	as	as	ADP
admet-3065	215	13	lipofectamine	lipofectamine	ADJ
admet-3065	215	14	,	,	PUNCT
admet-3065	215	15	while	while	SCONJ
admet-3065	215	16	exhibiting	exhibit	VERB
admet-3065	215	17	lower	low	ADJ
admet-3065	215	18	cytotoxicity	cytotoxicity	NOUN
admet-3065	215	19	[	[	X
admet-3065	215	20	110	110	NUM
admet-3065	215	21	]	]	PUNCT
admet-3065	215	22	.	.	PUNCT
admet-3065	216	1	similar	similar	ADJ
admet-3065	216	2	findings	finding	NOUN
admet-3065	216	3	were	be	AUX
admet-3065	216	4	observed	observe	VERB
admet-3065	216	5	with	with	ADP
admet-3065	216	6	carbamate	carbamate	NOUN
admet-3065	216	7	-	-	PUNCT
admet-3065	216	8	containing	contain	VERB
admet-3065	216	9	gemini	gemini	ADJ
admet-3065	216	10	quaternary	quaternary	ADJ
admet-3065	216	11	ammonium	ammonium	NOUN
admet-3065	216	12	lipids	lipids	ADP
admet-3065	216	13	[	[	X
admet-3065	216	14	58	58	NUM
admet-3065	216	15	]	]	PUNCT
admet-3065	216	16	.	.	PUNCT
admet-3065	217	1	due	due	ADP
admet-3065	217	2	to	to	ADP
admet-3065	217	3	their	their	PRON
admet-3065	217	4	high	high	ADJ
admet-3065	217	5	transfection	transfection	NOUN
admet-3065	217	6	efficiency	efficiency	NOUN
admet-3065	217	7	and	and	CCONJ
admet-3065	217	8	stability	stability	NOUN
admet-3065	217	9	in	in	ADP
admet-3065	217	10	extracellular	extracellular	ADJ
admet-3065	217	11	fluids	fluid	NOUN
admet-3065	217	12	,	,	PUNCT
admet-3065	217	13	carbamatelinked	carbamatelinke	VERB
admet-3065	217	14	lipids	lipid	NOUN
admet-3065	217	15	have	have	AUX
admet-3065	217	16	advanced	advance	VERB
admet-3065	217	17	to	to	PART
admet-3065	217	18	gene	gene	VERB
admet-3065	217	19	therapy	therapy	NOUN
admet-3065	217	20	clinical	clinical	ADJ
admet-3065	217	21	trials	trial	NOUN
admet-3065	217	22	[	[	X
admet-3065	217	23	111	111	NUM
admet-3065	217	24	]	]	PUNCT
admet-3065	217	25	.	.	PUNCT
admet-3065	218	1	amides	amide	VERB
admet-3065	218	2	amide	amide	NOUN
admet-3065	218	3	linkages	linkage	NOUN
admet-3065	218	4	,	,	PUNCT
admet-3065	218	5	commonly	commonly	ADV
admet-3065	218	6	found	find	VERB
admet-3065	218	7	in	in	ADP
admet-3065	218	8	peptides	peptide	NOUN
admet-3065	218	9	and	and	CCONJ
admet-3065	218	10	proteins	protein	NOUN
admet-3065	218	11	(	(	PUNCT
admet-3065	218	12	figure	figure	NOUN
admet-3065	218	13	3d	3d	NUM
admet-3065	218	14	)	)	PUNCT
admet-3065	218	15	,	,	PUNCT
admet-3065	218	16	are	be	AUX
admet-3065	218	17	exemplified	exemplify	VERB
admet-3065	218	18	by	by	ADP
admet-3065	218	19	dogs	dog	NOUN
admet-3065	218	20	,	,	PUNCT
admet-3065	218	21	a	a	DET
admet-3065	218	22	cationic	cationic	ADJ
admet-3065	218	23	lipid	lipid	NOUN
admet-3065	218	24	with	with	ADP
admet-3065	218	25	an	an	DET
admet-3065	218	26	amide	amide	NOUN
admet-3065	218	27	linker	linker	NOUN
admet-3065	218	28	connecting	connect	VERB
admet-3065	218	29	a	a	DET
admet-3065	218	30	spermine	spermine	NOUN
admet-3065	218	31	headgroup	headgroup	NOUN
admet-3065	218	32	to	to	ADP
admet-3065	218	33	a	a	DET
admet-3065	218	34	saturated	saturate	VERB
admet-3065	218	35	alkyl	alkyl	NOUN
admet-3065	218	36	chain	chain	NOUN
admet-3065	219	1	[	[	X
admet-3065	219	2	112	112	NUM
admet-3065	219	3	]	]	PUNCT
admet-3065	219	4	.	.	PUNCT
admet-3065	220	1	dogs	dog	NOUN
admet-3065	220	2	-	-	PUNCT
admet-3065	220	3	based	base	VERB
admet-3065	220	4	lipoplexes	lipoplexe	NOUN
admet-3065	220	5	exhibit	exhibit	VERB
admet-3065	220	6	superior	superior	ADJ
admet-3065	220	7	transfection	transfection	NOUN
admet-3065	220	8	efficiency	efficiency	NOUN
admet-3065	220	9	compared	compare	VERB
admet-3065	220	10	to	to	ADP
admet-3065	220	11	dotap	dotap	NOUN
admet-3065	220	12	,	,	PUNCT
admet-3065	220	13	partly	partly	ADV
admet-3065	220	14	due	due	ADP
admet-3065	220	15	to	to	ADP
admet-3065	220	16	their	their	PRON
admet-3065	220	17	ph	ph	VERB
admet-3065	220	18	-	-	PUNCT
admet-3065	220	19	buffering	buffering	NOUN
admet-3065	220	20	capacity	capacity	NOUN
admet-3065	220	21	[	[	X
admet-3065	220	22	112	112	NUM
admet-3065	220	23	]	]	PUNCT
admet-3065	220	24	.	.	PUNCT
admet-3065	221	1	amide	amide	NOUN
admet-3065	221	2	bond	bond	NOUN
admet-3065	221	3	hydrolysis	hydrolysis	NOUN
admet-3065	221	4	in	in	ADP
admet-3065	221	5	acidic	acidic	ADJ
admet-3065	221	6	endosomal	endosomal	ADJ
admet-3065	221	7	environments	environment	NOUN
admet-3065	221	8	follows	follow	VERB
admet-3065	221	9	a	a	DET
admet-3065	221	10	mechanism	mechanism	NOUN
admet-3065	221	11	similar	similar	ADJ
admet-3065	221	12	to	to	ADP
admet-3065	221	13	esters	ester	NOUN
admet-3065	221	14	,	,	PUNCT
admet-3065	221	15	involving	involve	VERB
admet-3065	221	16	protonation	protonation	NOUN
admet-3065	221	17	of	of	ADP
admet-3065	221	18	the	the	DET
admet-3065	221	19	carbonyl	carbonyl	NOUN
admet-3065	221	20	oxygen	oxygen	NOUN
admet-3065	221	21	and	and	CCONJ
admet-3065	221	22	nucleophilic	nucleophilic	ADJ
admet-3065	221	23	attack	attack	NOUN
admet-3065	221	24	by	by	ADP
admet-3065	221	25	water	water	NOUN
admet-3065	221	26	,	,	PUNCT
admet-3065	221	27	yielding	yield	VERB
admet-3065	221	28	a	a	DET
admet-3065	221	29	carboxylic	carboxylic	ADJ
admet-3065	221	30	acid	acid	NOUN
admet-3065	221	31	and	and	CCONJ
admet-3065	221	32	an	an	DET
admet-3065	221	33	ammonium	ammonium	NOUN
admet-3065	221	34	ion	ion	NOUN
admet-3065	221	35	[	[	X
admet-3065	221	36	65	65	NUM
admet-3065	221	37	]	]	PUNCT
admet-3065	221	38	.	.	PUNCT
admet-3065	222	1	amide	amide	NOUN
admet-3065	222	2	linkages	linkage	NOUN
admet-3065	222	3	are	be	AUX
admet-3065	222	4	more	more	ADV
admet-3065	222	5	stable	stable	ADJ
admet-3065	222	6	and	and	CCONJ
admet-3065	222	7	less	less	ADV
admet-3065	222	8	cytotoxic	cytotoxic	ADJ
admet-3065	222	9	than	than	ADP
admet-3065	222	10	esteror	esteror	NOUN
admet-3065	222	11	ether	ether	NOUN
admet-3065	222	12	-	-	PUNCT
admet-3065	222	13	based	base	VERB
admet-3065	222	14	linkers	linker	NOUN
admet-3065	222	15	,	,	PUNCT
admet-3065	222	16	particularly	particularly	ADV
admet-3065	222	17	in	in	ADP
admet-3065	222	18	ph	ph	ADJ
admet-3065	222	19	-	-	ADJ
admet-3065	222	20	sensitive	sensitive	ADJ
admet-3065	222	21	systems	system	NOUN
admet-3065	222	22	.	.	PUNCT
admet-3065	223	1	their	their	PRON
admet-3065	223	2	stability	stability	NOUN
admet-3065	223	3	is	be	AUX
admet-3065	223	4	attributed	attribute	VERB
admet-3065	223	5	to	to	ADP
admet-3065	223	6	intermolecular	intermolecular	ADJ
admet-3065	223	7	hydrogen	hydrogen	NOUN
admet-3065	223	8	bonding	bonding	NOUN
admet-3065	223	9	,	,	PUNCT
admet-3065	223	10	which	which	PRON
admet-3065	223	11	increases	increase	VERB
admet-3065	223	12	lipid	lipid	NOUN
admet-3065	223	13	melting	melting	NOUN
admet-3065	223	14	points	point	NOUN
admet-3065	223	15	and	and	CCONJ
admet-3065	223	16	structural	structural	ADJ
admet-3065	223	17	integrity	integrity	NOUN
admet-3065	223	18	[	[	X
admet-3065	223	19	39	39	NUM
admet-3065	223	20	]	]	PUNCT
admet-3065	223	21	,	,	PUNCT
admet-3065	223	22	confirming	confirm	VERB
admet-3065	223	23	that	that	SCONJ
admet-3065	223	24	amide	amide	NOUN
admet-3065	223	25	-	-	PUNCT
admet-3065	223	26	linked	link	VERB
admet-3065	223	27	lipids	lipid	NOUN
admet-3065	223	28	are	be	AUX
admet-3065	223	29	more	more	ADV
admet-3065	223	30	stable	stable	ADJ
admet-3065	223	31	and	and	CCONJ
admet-3065	223	32	effective	effective	ADJ
admet-3065	223	33	for	for	ADP
admet-3065	223	34	gene	gene	NOUN
admet-3065	223	35	transfection	transfection	NOUN
admet-3065	223	36	than	than	ADP
admet-3065	223	37	ester	ester	NOUN
admet-3065	223	38	-	-	PUNCT
admet-3065	223	39	linked	link	VERB
admet-3065	223	40	counterparts	counterpart	NOUN
admet-3065	223	41	[	[	X
admet-3065	223	42	113	113	NUM
admet-3065	223	43	]	]	PUNCT
admet-3065	223	44	.	.	PUNCT
admet-3065	224	1	the	the	DET
admet-3065	224	2	positional	positional	ADJ
admet-3065	224	3	orientation	orientation	NOUN
admet-3065	224	4	of	of	ADP
admet-3065	224	5	the	the	DET
admet-3065	224	6	amide	amide	NOUN
admet-3065	224	7	group	group	NOUN
admet-3065	224	8	relative	relative	ADJ
admet-3065	224	9	to	to	ADP
admet-3065	224	10	the	the	DET
admet-3065	224	11	cationic	cationic	ADJ
admet-3065	224	12	headgroup	headgroup	NOUN
admet-3065	224	13	also	also	ADV
admet-3065	224	14	influences	influence	VERB
admet-3065	224	15	transfection	transfection	NOUN
admet-3065	224	16	efficiency	efficiency	NOUN
admet-3065	224	17	,	,	PUNCT
admet-3065	224	18	with	with	ADP
admet-3065	224	19	classical	classical	ADJ
admet-3065	224	20	amide	amide	NOUN
admet-3065	224	21	configurations	configuration	NOUN
admet-3065	224	22	,	,	PUNCT
admet-3065	224	23	where	where	SCONJ
admet-3065	224	24	the	the	DET
admet-3065	224	25	amine	amine	NOUN
admet-3065	224	26	is	be	AUX
admet-3065	224	27	proximal	proximal	ADJ
admet-3065	224	28	to	to	ADP
admet-3065	224	29	the	the	DET
admet-3065	224	30	polar	polar	ADJ
admet-3065	224	31	head	head	NOUN
admet-3065	224	32	,	,	PUNCT
admet-3065	224	33	achieving	achieve	VERB
admet-3065	224	34	efficiencies	efficiency	NOUN
admet-3065	224	35	comparable	comparable	ADJ
admet-3065	224	36	to	to	ADP
admet-3065	224	37	lipofectamine	lipofectamine	NOUN
admet-3065	224	38	2000	2000	NUM
admet-3065	224	39	across	across	ADP
admet-3065	224	40	various	various	ADJ
admet-3065	224	41	cell	cell	NOUN
admet-3065	224	42	types	type	NOUN
admet-3065	224	43	,	,	PUNCT
admet-3065	224	44	whereas	whereas	SCONJ
admet-3065	224	45	reverse	reverse	VERB
admet-3065	224	46	isomeric	isomeric	ADJ
admet-3065	224	47	amide	amide	NOUN
admet-3065	224	48	bonds	bond	NOUN
admet-3065	224	49	reduce	reduce	VERB
admet-3065	224	50	efficiency	efficiency	NOUN
admet-3065	224	51	due	due	ADP
admet-3065	224	52	to	to	ADP
admet-3065	224	53	increased	increase	VERB
admet-3065	224	54	molecular	molecular	ADJ
admet-3065	224	55	rigidity	rigidity	NOUN
admet-3065	224	56	from	from	ADP
admet-3065	224	57	coulombic	coulombic	ADJ
admet-3065	224	58	repulsion	repulsion	NOUN
admet-3065	224	59	[	[	X
admet-3065	224	60	114	114	NUM
admet-3065	224	61	]	]	PUNCT
admet-3065	224	62	.	.	PUNCT
admet-3065	225	1	miscellaneous	miscellaneous	ADJ
admet-3065	225	2	less	less	ADV
admet-3065	225	3	common	common	ADJ
admet-3065	225	4	acid	acid	NOUN
admet-3065	225	5	-	-	PUNCT
admet-3065	225	6	labile	labile	ADJ
admet-3065	225	7	linkers	linker	NOUN
admet-3065	225	8	,	,	PUNCT
admet-3065	225	9	such	such	ADJ
admet-3065	225	10	as	as	ADP
admet-3065	225	11	acetals	acetal	NOUN
admet-3065	225	12	/	/	SYM
admet-3065	225	13	ketals	ketal	NOUN
admet-3065	225	14	and	and	CCONJ
admet-3065	225	15	hydrazones	hydrazone	NOUN
admet-3065	225	16	,	,	PUNCT
admet-3065	225	17	exhibit	exhibit	VERB
admet-3065	225	18	hydrolysis	hydrolysis	NOUN
admet-3065	225	19	rates	rate	NOUN
admet-3065	225	20	comparable	comparable	ADJ
admet-3065	225	21	to	to	ADP
admet-3065	225	22	carbamates	carbamate	NOUN
admet-3065	225	23	and	and	CCONJ
admet-3065	225	24	vinyl	vinyl	NOUN
admet-3065	225	25	ethers	ether	NOUN
admet-3065	225	26	[	[	X
admet-3065	225	27	115	115	NUM
admet-3065	225	28	]	]	PUNCT
admet-3065	225	29	.	.	PUNCT
admet-3065	226	1	ketal	ketal	ADJ
admet-3065	226	2	linkages	linkage	NOUN
admet-3065	226	3	,	,	PUNCT
admet-3065	226	4	in	in	ADP
admet-3065	226	5	particular	particular	ADJ
admet-3065	226	6	,	,	PUNCT
admet-3065	226	7	are	be	AUX
admet-3065	226	8	highly	highly	ADV
admet-3065	226	9	sensitive	sensitive	ADJ
admet-3065	226	10	to	to	ADP
admet-3065	226	11	endosomal	endosomal	ADJ
admet-3065	226	12	ph	ph	NOUN
admet-3065	226	13	while	while	SCONJ
admet-3065	226	14	remaining	remain	VERB
admet-3065	226	15	stable	stable	ADJ
admet-3065	226	16	at	at	ADP
admet-3065	226	17	physiological	physiological	ADJ
admet-3065	226	18	ph	ph	NOUN
admet-3065	226	19	,	,	PUNCT
admet-3065	226	20	making	make	VERB
admet-3065	226	21	them	they	PRON
admet-3065	226	22	ideal	ideal	ADJ
admet-3065	226	23	for	for	ADP
admet-3065	226	24	circulation	circulation	NOUN
admet-3065	226	25	-	-	PUNCT
admet-3065	226	26	stable	stable	ADJ
admet-3065	226	27	,	,	PUNCT
admet-3065	226	28	intracellularly	intracellularly	ADV
admet-3065	226	29	responsive	responsive	ADJ
admet-3065	226	30	systems	system	NOUN
admet-3065	226	31	[	[	X
admet-3065	226	32	39	39	NUM
admet-3065	226	33	]	]	PUNCT
admet-3065	226	34	.	.	PUNCT
admet-3065	227	1	acylhydrazone	acylhydrazone	NOUN
admet-3065	227	2	bonds	bond	NOUN
admet-3065	227	3	also	also	ADV
admet-3065	227	4	hydrolyse	hydrolyse	VERB
admet-3065	227	5	rapidly	rapidly	ADV
admet-3065	227	6	in	in	ADP
admet-3065	227	7	acidic	acidic	ADJ
admet-3065	227	8	lysosomal	lysosomal	ADJ
admet-3065	227	9	environments	environment	NOUN
admet-3065	227	10	[	[	X
admet-3065	227	11	116	116	NUM
admet-3065	227	12	]	]	PUNCT
admet-3065	227	13	.	.	PUNCT
admet-3065	228	1	redox	redox	NOUN
admet-3065	228	2	-	-	PUNCT
admet-3065	228	3	sensitive	sensitive	ADJ
admet-3065	228	4	disulfide	disulfide	NOUN
admet-3065	228	5	(	(	PUNCT
admet-3065	228	6	-s	-s	NOUN
admet-3065	228	7	-	-	PUNCT
admet-3065	228	8	s-	s-	NOUN
admet-3065	228	9	)	)	PUNCT
admet-3065	228	10	linkers	linker	NOUN
admet-3065	228	11	enable	enable	VERB
admet-3065	228	12	spatially	spatially	ADV
admet-3065	228	13	and	and	CCONJ
admet-3065	228	14	temporally	temporally	ADV
admet-3065	228	15	controlled	control	VERB
admet-3065	228	16	lipoplex	lipoplex	NOUN
admet-3065	228	17	disassembly	disassembly	NOUN
admet-3065	228	18	and	and	CCONJ
admet-3065	228	19	na	na	PART
admet-3065	228	20	release	release	VERB
admet-3065	228	21	by	by	ADP
admet-3065	228	22	responding	respond	VERB
admet-3065	228	23	to	to	ADP
admet-3065	228	24	intracellular	intracellular	ADJ
admet-3065	228	25	reducing	reduce	VERB
admet-3065	228	26	agents	agent	NOUN
admet-3065	228	27	like	like	ADP
admet-3065	228	28	glutathione	glutathione	NOUN
admet-3065	228	29	(	(	PUNCT
admet-3065	228	30	gsh	gsh	PROPN
admet-3065	228	31	)	)	PUNCT
admet-3065	229	1	[	[	X
admet-3065	229	2	117	117	NUM
admet-3065	229	3	]	]	PUNCT
admet-3065	229	4	.	.	PUNCT
admet-3065	230	1	disulfide	disulfide	NOUN
admet-3065	230	2	linkers	linker	NOUN
admet-3065	230	3	are	be	AUX
admet-3065	230	4	particularly	particularly	ADV
admet-3065	230	5	effective	effective	ADJ
admet-3065	230	6	for	for	ADP
admet-3065	230	7	sirna	sirna	PROPN
admet-3065	230	8	delivery	delivery	NOUN
admet-3065	230	9	,	,	PUNCT
admet-3065	230	10	with	with	ADP
admet-3065	230	11	cysteine	cysteine	NOUN
admet-3065	230	12	-	-	PUNCT
admet-3065	230	13	containing	contain	VERB
admet-3065	230	14	linkers	linker	NOUN
admet-3065	230	15	enhancing	enhance	VERB
admet-3065	230	16	structural	structural	ADJ
admet-3065	230	17	stability	stability	NOUN
admet-3065	230	18	and	and	CCONJ
admet-3065	230	19	controlling	control	VERB
admet-3065	230	20	cytoplasmic	cytoplasmic	ADJ
admet-3065	230	21	release	release	NOUN
admet-3065	230	22	[	[	X
admet-3065	230	23	118	118	NUM
admet-3065	230	24	]	]	PUNCT
admet-3065	230	25	.	.	PUNCT
admet-3065	231	1	enzyme	enzyme	NOUN
admet-3065	231	2	-	-	PUNCT
admet-3065	231	3	cleavable	cleavable	ADJ
admet-3065	231	4	linkers	linker	NOUN
admet-3065	231	5	offer	offer	VERB
admet-3065	231	6	site	site	NOUN
admet-3065	231	7	-	-	PUNCT
admet-3065	231	8	specific	specific	ADJ
admet-3065	231	9	na	na	NOUN
admet-3065	231	10	delivery	delivery	NOUN
admet-3065	231	11	regulated	regulate	VERB
admet-3065	231	12	by	by	ADP
admet-3065	231	13	target	target	NOUN
admet-3065	231	14	enzyme	enzyme	NOUN
admet-3065	231	15	activity	activity	NOUN
admet-3065	231	16	.	.	PUNCT
admet-3065	232	1	for	for	ADP
admet-3065	232	2	instance	instance	NOUN
admet-3065	232	3	,	,	PUNCT
admet-3065	232	4	the	the	DET
admet-3065	232	5	pegpeptide	pegpeptide	NOUN
admet-3065	232	6	-	-	PUNCT
admet-3065	232	7	dope	dope	NOUN
admet-3065	232	8	(	(	PUNCT
admet-3065	232	9	peg	peg	NOUN
admet-3065	232	10	-	-	PUNCT
admet-3065	232	11	pd	pd	NOUN
admet-3065	232	12	)	)	PUNCT
admet-3065	232	13	system	system	NOUN
admet-3065	232	14	disassembles	disassemble	VERB
admet-3065	232	15	upon	upon	SCONJ
admet-3065	232	16	peptide	peptide	NOUN
admet-3065	232	17	cleavage	cleavage	NOUN
admet-3065	232	18	by	by	ADP
admet-3065	232	19	matrix	matrix	NOUN
admet-3065	232	20	metalloproteinase-2	metalloproteinase-2	NUM
admet-3065	232	21	(	(	PUNCT
admet-3065	232	22	mmp-2	mmp-2	NUM
admet-3065	232	23	)	)	PUNCT
admet-3065	232	24	,	,	PUNCT
admet-3065	232	25	an	an	DET
admet-3065	232	26	enzyme	enzyme	NOUN
admet-3065	232	27	overexpressed	overexpresse	VERB
admet-3065	232	28	at	at	ADP
admet-3065	232	29	pathological	pathological	ADJ
admet-3065	232	30	sites	site	NOUN
admet-3065	232	31	[	[	X
admet-3065	232	32	119	119	NUM
admet-3065	232	33	]	]	PUNCT
admet-3065	232	34	.	.	PUNCT
admet-3065	233	1	photosensitive	photosensitive	ADJ
admet-3065	233	2	linkers	linker	NOUN
admet-3065	233	3	provide	provide	VERB
admet-3065	233	4	an	an	DET
admet-3065	233	5	alternative	alternative	NOUN
admet-3065	233	6	for	for	ADP
admet-3065	233	7	stimulusresponsive	stimulusresponsive	ADJ
admet-3065	233	8	gene	gene	NOUN
admet-3065	233	9	delivery	delivery	NOUN
admet-3065	233	10	.	.	PUNCT
admet-3065	234	1	uv	uv	NOUN
admet-3065	234	2	-	-	PUNCT
admet-3065	234	3	sensitive	sensitive	ADJ
admet-3065	234	4	cationic	cationic	ADJ
admet-3065	234	5	amphiphiles	amphiphile	NOUN
admet-3065	234	6	,	,	PUNCT
admet-3065	234	7	demonstrating	demonstrate	VERB
admet-3065	234	8	that	that	SCONJ
admet-3065	234	9	photolytic	photolytic	ADJ
admet-3065	234	10	linker	linker	NOUN
admet-3065	234	11	cleavage	cleavage	NOUN
admet-3065	234	12	enabled	enable	VERB
admet-3065	234	13	endosomal	endosomal	NOUN
admet-3065	234	14	na	na	PART
admet-3065	234	15	release	release	VERB
admet-3065	234	16	,	,	PUNCT
admet-3065	234	17	achieving	achieve	VERB
admet-3065	234	18	transfection	transfection	NOUN
admet-3065	234	19	efficiencies	efficiency	NOUN
admet-3065	234	20	up	up	ADP
admet-3065	234	21	to	to	PART
admet-3065	234	22	20	20	NUM
admet-3065	234	23	-	-	NUM
admet-3065	234	24	fold	fold	VERB
admet-3065	234	25	higher	high	ADJ
admet-3065	234	26	than	than	ADP
admet-3065	234	27	lipofectin	lipofectin	VERB
admet-3065	234	28	[	[	X
admet-3065	234	29	120	120	NUM
admet-3065	234	30	]	]	PUNCT
admet-3065	234	31	.	.	PUNCT
admet-3065	235	1	collectively	collectively	ADV
admet-3065	235	2	,	,	PUNCT
admet-3065	235	3	these	these	DET
admet-3065	235	4	findings	finding	NOUN
admet-3065	235	5	highlight	highlight	VERB
admet-3065	235	6	the	the	DET
admet-3065	235	7	critical	critical	ADJ
admet-3065	235	8	role	role	NOUN
admet-3065	235	9	of	of	ADP
admet-3065	235	10	linker	linker	NOUN
admet-3065	235	11	chemistry	chemistry	NOUN
admet-3065	235	12	in	in	ADP
admet-3065	235	13	modulating	modulate	VERB
admet-3065	235	14	lipoplex	lipoplex	NOUN
admet-3065	235	15	stability	stability	NOUN
admet-3065	235	16	,	,	PUNCT
admet-3065	235	17	cytotoxicity	cytotoxicity	NOUN
admet-3065	235	18	,	,	PUNCT
admet-3065	235	19	and	and	CCONJ
admet-3065	235	20	transfection	transfection	NOUN
admet-3065	235	21	efficiency	efficiency	NOUN
admet-3065	235	22	.	.	PUNCT
admet-3065	236	1	biodegradable	biodegradable	ADJ
admet-3065	236	2	,	,	PUNCT
admet-3065	236	3	stimulus	stimulus	ADJ
admet-3065	236	4	-	-	PUNCT
admet-3065	236	5	responsive	responsive	ADJ
admet-3065	236	6	linkers	linker	NOUN
admet-3065	236	7	,	,	PUNCT
admet-3065	236	8	particularly	particularly	ADV
admet-3065	236	9	carbamates	carbamate	NOUN
admet-3065	236	10	and	and	CCONJ
admet-3065	236	11	disulfides	disulfide	NOUN
admet-3065	236	12	,	,	PUNCT
admet-3065	236	13	are	be	AUX
admet-3065	236	14	particularly	particularly	ADV
admet-3065	236	15	promising	promising	ADJ
admet-3065	236	16	due	due	ADP
admet-3065	236	17	to	to	ADP
admet-3065	236	18	their	their	PRON
admet-3065	236	19	ability	ability	NOUN
admet-3065	236	20	to	to	PART
admet-3065	236	21	combine	combine	VERB
admet-3065	236	22	high	high	ADJ
admet-3065	236	23	transfection	transfection	NOUN
admet-3065	236	24	activity	activity	NOUN
admet-3065	236	25	with	with	ADP
admet-3065	236	26	low	low	ADJ
admet-3065	236	27	toxicity	toxicity	NOUN
admet-3065	236	28	.	.	PUNCT
admet-3065	237	1	tails	tail	NOUN
admet-3065	237	2	(	(	PUNCT
admet-3065	237	3	hydrophobic	hydrophobic	NOUN
admet-3065	237	4	region	region	NOUN
admet-3065	237	5	)	)	PUNCT
admet-3065	237	6	the	the	DET
admet-3065	237	7	hydrophobic	hydrophobic	NOUN
admet-3065	237	8	tail	tail	NOUN
admet-3065	237	9	moiety	moiety	NOUN
admet-3065	237	10	of	of	ADP
admet-3065	237	11	cationic	cationic	ADJ
admet-3065	237	12	lipids	lipid	NOUN
admet-3065	237	13	is	be	AUX
admet-3065	237	14	a	a	DET
admet-3065	237	15	critical	critical	ADJ
admet-3065	237	16	determinant	determinant	NOUN
admet-3065	237	17	of	of	ADP
admet-3065	237	18	lipoplex	lipoplex	ADJ
admet-3065	237	19	physicochemical	physicochemical	ADJ
admet-3065	237	20	properties	property	NOUN
admet-3065	237	21	,	,	PUNCT
admet-3065	237	22	influencing	influence	VERB
admet-3065	237	23	phase	phase	NOUN
admet-3065	237	24	behaviour	behaviour	NOUN
admet-3065	237	25	,	,	PUNCT
admet-3065	237	26	membrane	membrane	ADJ
admet-3065	237	27	fluidity	fluidity	NOUN
admet-3065	237	28	,	,	PUNCT
admet-3065	237	29	lipoplex	lipoplex	NOUN
admet-3065	237	30	stability	stability	NOUN
admet-3065	237	31	,	,	PUNCT
admet-3065	237	32	and	and	CCONJ
admet-3065	237	33	cytotoxicity	cytotoxicity	NOUN
admet-3065	237	34	,	,	PUNCT
admet-3065	237	35	as	as	SCONJ
admet-3065	237	36	established	establish	VERB
admet-3065	237	37	e.	e.	PROPN
admet-3065	237	38	j.	j.	PROPN
admet-3065	237	39	saleh	saleh	PROPN
admet-3065	237	40	et	et	PROPN
admet-3065	237	41	al	al	PROPN
admet-3065	237	42	.	.	PROPN
admet-3065	237	43	admet	admet	PROPN
admet-3065	237	44	&	&	CCONJ
admet-3065	237	45	dmpk	dmpk	PROPN
admet-3065	237	46	00(0	00(0	PROPN
admet-3065	237	47	)	)	PUNCT
admet-3065	237	48	(	(	PUNCT
admet-3065	237	49	2025	2025	NUM
admet-3065	237	50	)	)	PUNCT
admet-3065	237	51	3065	3065	NUM
admet-3065	237	52	12	12	NUM
admet-3065	237	53	through	through	ADP
admet-3065	237	54	structure	structure	NOUN
admet-3065	237	55	-	-	PUNCT
admet-3065	237	56	activity	activity	NOUN
admet-3065	237	57	relationship	relationship	NOUN
admet-3065	237	58	(	(	PUNCT
admet-3065	237	59	sar	sar	PROPN
admet-3065	237	60	)	)	PUNCT
admet-3065	237	61	studies	study	NOUN
admet-3065	237	62	[	[	X
admet-3065	237	63	121	121	NUM
admet-3065	237	64	]	]	PUNCT
admet-3065	237	65	.	.	PUNCT
admet-3065	238	1	these	these	DET
admet-3065	238	2	non	non	ADJ
admet-3065	238	3	-	-	ADJ
admet-3065	238	4	polar	polar	ADJ
admet-3065	238	5	tails	tail	NOUN
admet-3065	238	6	are	be	AUX
admet-3065	238	7	broadly	broadly	ADV
admet-3065	238	8	categorized	categorize	VERB
admet-3065	238	9	into	into	ADP
admet-3065	238	10	aliphatic	aliphatic	ADJ
admet-3065	238	11	chains	chain	NOUN
admet-3065	238	12	or	or	CCONJ
admet-3065	238	13	cyclic	cyclic	NOUN
admet-3065	238	14	,	,	PUNCT
admet-3065	238	15	steroid	steroid	NOUN
admet-3065	238	16	-	-	PUNCT
admet-3065	238	17	like	like	ADJ
admet-3065	238	18	structures	structure	NOUN
admet-3065	238	19	based	base	VERB
admet-3065	238	20	on	on	ADP
admet-3065	238	21	their	their	PRON
admet-3065	238	22	structural	structural	ADJ
admet-3065	238	23	features	feature	NOUN
admet-3065	238	24	.	.	PUNCT
admet-3065	239	1	aliphatic	aliphatic	ADJ
admet-3065	239	2	chains	chain	NOUN
admet-3065	239	3	aliphatic	aliphatic	ADJ
admet-3065	239	4	tails	tail	NOUN
admet-3065	239	5	,	,	PUNCT
admet-3065	239	6	consisting	consist	VERB
admet-3065	239	7	of	of	ADP
admet-3065	239	8	saturated	saturated	ADJ
admet-3065	239	9	or	or	CCONJ
admet-3065	239	10	unsaturated	unsaturated	ADJ
admet-3065	239	11	hydrocarbon	hydrocarbon	NOUN
admet-3065	239	12	chains	chain	NOUN
admet-3065	239	13	,	,	PUNCT
admet-3065	239	14	significantly	significantly	ADV
admet-3065	239	15	govern	govern	VERB
admet-3065	239	16	lipoplex	lipoplex	ADJ
admet-3065	239	17	performance	performance	NOUN
admet-3065	239	18	.	.	PUNCT
admet-3065	240	1	factors	factor	NOUN
admet-3065	240	2	such	such	ADJ
admet-3065	240	3	as	as	ADP
admet-3065	240	4	chain	chain	NOUN
admet-3065	240	5	length	length	NOUN
admet-3065	240	6	,	,	PUNCT
admet-3065	240	7	degree	degree	NOUN
admet-3065	240	8	of	of	ADP
admet-3065	240	9	unsaturation	unsaturation	NOUN
admet-3065	240	10	,	,	PUNCT
admet-3065	240	11	and	and	CCONJ
admet-3065	240	12	the	the	DET
admet-3065	240	13	number	number	NOUN
admet-3065	240	14	of	of	ADP
admet-3065	240	15	chains	chain	NOUN
admet-3065	240	16	per	per	ADP
admet-3065	240	17	lipid	lipid	NOUN
admet-3065	240	18	molecule	molecule	NOUN
admet-3065	240	19	are	be	AUX
admet-3065	240	20	known	know	VERB
admet-3065	240	21	to	to	PART
admet-3065	240	22	affect	affect	VERB
admet-3065	240	23	transfection	transfection	NOUN
admet-3065	240	24	efficiency	efficiency	NOUN
admet-3065	240	25	[	[	X
admet-3065	240	26	122	122	NUM
admet-3065	240	27	]	]	PUNCT
admet-3065	240	28	,	,	PUNCT
admet-3065	240	29	yet	yet	CCONJ
admet-3065	240	30	there	there	PRON
admet-3065	240	31	is	be	VERB
admet-3065	240	32	no	no	DET
admet-3065	240	33	universal	universal	ADJ
admet-3065	240	34	agreement	agreement	NOUN
admet-3065	240	35	on	on	ADP
admet-3065	240	36	the	the	DET
admet-3065	240	37	optimal	optimal	ADJ
admet-3065	240	38	tail	tail	NOUN
admet-3065	240	39	configuration	configuration	NOUN
admet-3065	240	40	[	[	X
admet-3065	240	41	19	19	NUM
admet-3065	240	42	]	]	PUNCT
admet-3065	240	43	.	.	PUNCT
admet-3065	241	1	generally	generally	ADV
admet-3065	241	2	,	,	PUNCT
admet-3065	241	3	shorter	short	ADJ
admet-3065	241	4	saturated	saturate	VERB
admet-3065	241	5	chains	chain	NOUN
admet-3065	241	6	enhance	enhance	VERB
admet-3065	241	7	transfection	transfection	NOUN
admet-3065	241	8	,	,	PUNCT
admet-3065	241	9	with	with	ADP
admet-3065	241	10	some	some	DET
admet-3065	241	11	studies	study	NOUN
admet-3065	241	12	indicating	indicate	VERB
admet-3065	241	13	optimal	optimal	ADJ
admet-3065	241	14	performance	performance	NOUN
admet-3065	241	15	for	for	ADP
admet-3065	241	16	chains	chain	NOUN
admet-3065	241	17	of	of	ADP
admet-3065	241	18	10	10	NUM
admet-3065	241	19	-	-	SYM
admet-3065	241	20	14	14	NUM
admet-3065	241	21	carbons	carbon	NOUN
admet-3065	241	22	[	[	X
admet-3065	241	23	123	123	NUM
admet-3065	241	24	]	]	PUNCT
admet-3065	241	25	.	.	PUNCT
admet-3065	242	1	however	however	ADV
admet-3065	242	2	,	,	PUNCT
admet-3065	242	3	other	other	ADJ
admet-3065	242	4	investigations	investigation	NOUN
admet-3065	242	5	,	,	PUNCT
admet-3065	242	6	including	include	VERB
admet-3065	242	7	our	our	PRON
admet-3065	242	8	own	own	ADJ
admet-3065	242	9	,	,	PUNCT
admet-3065	242	10	suggest	suggest	VERB
admet-3065	242	11	a	a	DET
admet-3065	242	12	bell	bell	NOUN
admet-3065	242	13	-	-	PUNCT
admet-3065	242	14	shaped	shape	VERB
admet-3065	242	15	relationship	relationship	NOUN
admet-3065	242	16	,	,	PUNCT
admet-3065	242	17	with	with	ADP
admet-3065	242	18	peak	peak	NOUN
admet-3065	242	19	efficiency	efficiency	NOUN
admet-3065	242	20	at	at	ADP
admet-3065	242	21	c14	c14	NOUN
admet-3065	242	22	,	,	PUNCT
admet-3065	242	23	diminishing	diminish	VERB
admet-3065	242	24	for	for	ADP
admet-3065	242	25	both	both	CCONJ
admet-3065	242	26	shorter	short	ADJ
admet-3065	242	27	and	and	CCONJ
admet-3065	242	28	longer	long	ADJ
admet-3065	242	29	chains	chain	NOUN
admet-3065	242	30	[	[	X
admet-3065	242	31	124	124	NUM
admet-3065	242	32	]	]	PUNCT
admet-3065	242	33	.	.	PUNCT
admet-3065	243	1	the	the	DET
admet-3065	243	2	number	number	NOUN
admet-3065	243	3	of	of	ADP
admet-3065	243	4	hydrophobic	hydrophobic	NOUN
admet-3065	243	5	chains	chain	NOUN
admet-3065	243	6	per	per	ADP
admet-3065	243	7	lipid	lipid	NOUN
admet-3065	243	8	molecule	molecule	NOUN
admet-3065	243	9	remains	remain	VERB
admet-3065	243	10	a	a	DET
admet-3065	243	11	subject	subject	NOUN
admet-3065	243	12	of	of	ADP
admet-3065	243	13	debate	debate	NOUN
admet-3065	243	14	.	.	PUNCT
admet-3065	244	1	double	double	ADJ
admet-3065	244	2	-	-	PUNCT
admet-3065	244	3	tailed	tail	VERB
admet-3065	244	4	cationic	cationic	ADJ
admet-3065	244	5	lipids	lipid	NOUN
admet-3065	244	6	,	,	PUNCT
admet-3065	244	7	such	such	ADJ
admet-3065	244	8	as	as	ADP
admet-3065	244	9	dotma	dotma	ADJ
admet-3065	244	10	,	,	PUNCT
admet-3065	244	11	dotap	dotap	NOUN
admet-3065	244	12	,	,	PUNCT
admet-3065	244	13	dopsa	dopsa	NOUN
admet-3065	244	14	,	,	PUNCT
admet-3065	244	15	dorie	dorie	ADJ
admet-3065	244	16	,	,	PUNCT
admet-3065	244	17	and	and	CCONJ
admet-3065	244	18	dogs	dog	NOUN
admet-3065	244	19	,	,	PUNCT
admet-3065	244	20	generally	generally	ADV
admet-3065	244	21	outperform	outperform	VERB
admet-3065	244	22	their	their	PRON
admet-3065	244	23	single	single	ADJ
admet-3065	244	24	-	-	PUNCT
admet-3065	244	25	tailed	tail	VERB
admet-3065	244	26	counterparts	counterpart	NOUN
admet-3065	244	27	,	,	PUNCT
admet-3065	244	28	likely	likely	ADJ
admet-3065	244	29	due	due	ADP
admet-3065	244	30	to	to	ADP
admet-3065	244	31	their	their	PRON
admet-3065	244	32	ability	ability	NOUN
admet-3065	244	33	to	to	PART
admet-3065	244	34	form	form	VERB
admet-3065	244	35	stable	stable	ADJ
admet-3065	244	36	aggregates	aggregate	NOUN
admet-3065	244	37	in	in	ADP
admet-3065	244	38	aqueous	aqueous	ADJ
admet-3065	244	39	environments	environment	NOUN
admet-3065	244	40	,	,	PUNCT
admet-3065	244	41	which	which	PRON
admet-3065	244	42	is	be	AUX
admet-3065	244	43	influenced	influence	VERB
admet-3065	244	44	by	by	ADP
admet-3065	244	45	molecular	molecular	ADJ
admet-3065	244	46	geometry	geometry	NOUN
admet-3065	244	47	and	and	CCONJ
admet-3065	244	48	chemical	chemical	NOUN
admet-3065	244	49	properties	property	NOUN
admet-3065	244	50	[	[	X
admet-3065	244	51	125	125	NUM
admet-3065	244	52	]	]	PUNCT
admet-3065	244	53	.	.	PUNCT
admet-3065	245	1	single	single	ADJ
admet-3065	245	2	-	-	PUNCT
admet-3065	245	3	tailed	tail	VERB
admet-3065	245	4	lipids	lipid	NOUN
admet-3065	245	5	often	often	ADV
admet-3065	245	6	form	form	VERB
admet-3065	245	7	less	less	ADV
admet-3065	245	8	stable	stable	ADJ
admet-3065	245	9	,	,	PUNCT
admet-3065	245	10	more	more	ADJ
admet-3065	245	11	cytotoxic	cytotoxic	ADJ
admet-3065	245	12	complexes	complex	NOUN
admet-3065	245	13	[	[	X
admet-3065	245	14	126	126	NUM
admet-3065	245	15	]	]	PUNCT
admet-3065	245	16	.	.	PUNCT
admet-3065	246	1	notably	notably	ADV
admet-3065	246	2	,	,	PUNCT
admet-3065	246	3	mixed	mixed	ADJ
admet-3065	246	4	formulations	formulation	NOUN
admet-3065	246	5	combining	combine	VERB
admet-3065	246	6	singleand	singleand	NOUN
admet-3065	246	7	double	double	ADJ
admet-3065	246	8	-	-	PUNCT
admet-3065	246	9	tailed	tail	VERB
admet-3065	246	10	lipids	lipid	NOUN
admet-3065	246	11	can	can	AUX
admet-3065	246	12	synergistically	synergistically	ADV
admet-3065	246	13	enhance	enhance	VERB
admet-3065	246	14	transfection	transfection	NOUN
admet-3065	246	15	efficiency	efficiency	NOUN
admet-3065	246	16	[	[	X
admet-3065	246	17	127	127	NUM
admet-3065	246	18	]	]	SYM
admet-3065	246	19	.	.	PUNCT
admet-3065	247	1	unsaturated	unsaturate	VERB
admet-3065	247	2	alkyl	alkyl	NOUN
admet-3065	247	3	chains	chain	NOUN
admet-3065	247	4	are	be	AUX
admet-3065	247	5	widely	widely	ADV
admet-3065	247	6	recognized	recognize	VERB
admet-3065	247	7	for	for	ADP
admet-3065	247	8	enhancing	enhance	VERB
admet-3065	247	9	transfection	transfection	NOUN
admet-3065	247	10	due	due	ADP
admet-3065	247	11	to	to	ADP
admet-3065	247	12	increased	increase	VERB
admet-3065	247	13	membrane	membrane	NOUN
admet-3065	247	14	fluidity	fluidity	NOUN
admet-3065	247	15	and	and	CCONJ
admet-3065	247	16	fusogenic	fusogenic	ADJ
admet-3065	247	17	properties	property	NOUN
admet-3065	247	18	[	[	X
admet-3065	247	19	128	128	NUM
admet-3065	247	20	]	]	PUNCT
admet-3065	247	21	.	.	PUNCT
admet-3065	248	1	the	the	DET
admet-3065	248	2	degree	degree	NOUN
admet-3065	248	3	,	,	PUNCT
admet-3065	248	4	position	position	NOUN
admet-3065	248	5	,	,	PUNCT
admet-3065	248	6	and	and	CCONJ
admet-3065	248	7	configuration	configuration	NOUN
admet-3065	248	8	of	of	ADP
admet-3065	248	9	double	double	ADJ
admet-3065	248	10	bonds	bond	NOUN
admet-3065	248	11	are	be	AUX
admet-3065	248	12	critical	critical	ADJ
admet-3065	248	13	[	[	X
admet-3065	248	14	129	129	NUM
admet-3065	248	15	]	]	PUNCT
admet-3065	248	16	.	.	PUNCT
admet-3065	249	1	while	while	SCONJ
admet-3065	249	2	few	few	ADJ
admet-3065	249	3	studies	study	NOUN
admet-3065	249	4	directly	directly	ADV
admet-3065	249	5	correlate	correlate	VERB
admet-3065	249	6	unsaturation	unsaturation	NOUN
admet-3065	249	7	with	with	ADP
admet-3065	249	8	transfection	transfection	NOUN
admet-3065	249	9	efficiency	efficiency	NOUN
admet-3065	249	10	,	,	PUNCT
admet-3065	249	11	monounsaturated	monounsaturate	VERB
admet-3065	249	12	tails	tail	NOUN
admet-3065	249	13	are	be	AUX
admet-3065	249	14	generally	generally	ADV
admet-3065	249	15	most	most	ADV
admet-3065	249	16	effective	effective	ADJ
admet-3065	249	17	[	[	X
admet-3065	249	18	122	122	NUM
admet-3065	249	19	]	]	PUNCT
admet-3065	249	20	.	.	PUNCT
admet-3065	250	1	it	it	PRON
admet-3065	250	2	was	be	AUX
admet-3065	250	3	confirmed	confirm	VERB
admet-3065	250	4	that	that	SCONJ
admet-3065	250	5	c18	c18	NOUN
admet-3065	250	6	monounsaturated	monounsaturate	VERB
admet-3065	250	7	single	single	ADJ
admet-3065	250	8	-	-	PUNCT
admet-3065	250	9	tailed	tail	VERB
admet-3065	250	10	lipids	lipid	NOUN
admet-3065	250	11	excel	excel	VERB
admet-3065	250	12	in	in	ADP
admet-3065	250	13	dna	dna	PROPN
admet-3065	250	14	condensation	condensation	NOUN
admet-3065	250	15	and	and	CCONJ
admet-3065	250	16	transfection	transfection	NOUN
admet-3065	250	17	.	.	PUNCT
admet-3065	251	1	additionally	additionally	ADV
admet-3065	251	2	,	,	PUNCT
admet-3065	251	3	the	the	DET
admet-3065	251	4	cis	cis	NOUN
admet-3065	251	5	configuration	configuration	NOUN
admet-3065	251	6	of	of	ADP
admet-3065	251	7	unsaturated	unsaturated	ADJ
admet-3065	251	8	chains	chain	NOUN
admet-3065	251	9	consistently	consistently	ADV
admet-3065	251	10	outperforms	outperform	VERB
admet-3065	251	11	the	the	DET
admet-3065	251	12	trans	trans	PROPN
admet-3065	251	13	configuration	configuration	NOUN
admet-3065	251	14	[	[	X
admet-3065	251	15	130	130	NUM
admet-3065	251	16	]	]	PUNCT
admet-3065	251	17	.	.	PUNCT
admet-3065	252	1	cyclic	cyclic	NOUN
admet-3065	252	2	(	(	PUNCT
admet-3065	252	3	steroid	steroid	NOUN
admet-3065	252	4	-	-	PUNCT
admet-3065	252	5	based	base	VERB
admet-3065	252	6	)	)	PUNCT
admet-3065	252	7	domains	domain	NOUN
admet-3065	252	8	since	since	SCONJ
admet-3065	252	9	the	the	DET
admet-3065	252	10	development	development	NOUN
admet-3065	252	11	of	of	ADP
admet-3065	252	12	dc	dc	PROPN
admet-3065	252	13	-	-	PUNCT
admet-3065	252	14	chol	chol	NOUN
admet-3065	252	15	,	,	PUNCT
admet-3065	252	16	a	a	DET
admet-3065	252	17	cholesterol	cholesterol	NOUN
admet-3065	252	18	-	-	PUNCT
admet-3065	252	19	based	base	VERB
admet-3065	252	20	cationic	cationic	ADJ
admet-3065	252	21	lipid	lipid	NOUN
admet-3065	252	22	,	,	PUNCT
admet-3065	252	23	steroid	steroid	NOUN
admet-3065	252	24	-	-	PUNCT
admet-3065	252	25	based	base	VERB
admet-3065	252	26	transfectants	transfectant	NOUN
admet-3065	252	27	have	have	AUX
admet-3065	252	28	gained	gain	VERB
admet-3065	252	29	prominence	prominence	NOUN
admet-3065	252	30	[	[	X
admet-3065	252	31	62	62	NUM
admet-3065	252	32	]	]	PUNCT
admet-3065	252	33	.	.	PUNCT
admet-3065	253	1	cholesterol	cholesterol	NOUN
admet-3065	253	2	is	be	AUX
admet-3065	253	3	frequently	frequently	ADV
admet-3065	253	4	utilized	utilize	VERB
admet-3065	253	5	due	due	ADP
admet-3065	253	6	to	to	ADP
admet-3065	253	7	its	its	PRON
admet-3065	253	8	rigidity	rigidity	NOUN
admet-3065	253	9	,	,	PUNCT
admet-3065	253	10	biodegradability	biodegradability	NOUN
admet-3065	253	11	,	,	PUNCT
admet-3065	253	12	biocompatibility	biocompatibility	NOUN
admet-3065	253	13	,	,	PUNCT
admet-3065	253	14	and	and	CCONJ
admet-3065	253	15	fusogenic	fusogenic	ADJ
admet-3065	253	16	properties	property	NOUN
admet-3065	253	17	[	[	X
admet-3065	253	18	131	131	NUM
admet-3065	253	19	]	]	PUNCT
admet-3065	253	20	.	.	PUNCT
admet-3065	254	1	for	for	ADP
admet-3065	254	2	instance	instance	NOUN
admet-3065	254	3	,	,	PUNCT
admet-3065	254	4	synthesized	synthesize	VERB
admet-3065	254	5	cholesteryloxypropan-1	cholesteryloxypropan-1	NOUN
admet-3065	254	6	-	-	ADJ
admet-3065	254	7	amine	amine	ADJ
admet-3065	254	8	(	(	PUNCT
admet-3065	254	9	copa	copa	NOUN
admet-3065	254	10	)	)	PUNCT
admet-3065	254	11	and	and	CCONJ
admet-3065	254	12	cholesteryl-2	cholesteryl-2	NUM
admet-3065	254	13	-	-	PUNCT
admet-3065	254	14	aminoethylcarbamate	aminoethylcarbamate	NOUN
admet-3065	254	15	(	(	PUNCT
admet-3065	254	16	caec	caec	NOUN
admet-3065	254	17	)	)	PUNCT
admet-3065	254	18	,	,	PUNCT
admet-3065	254	19	which	which	PRON
admet-3065	254	20	exhibited	exhibit	VERB
admet-3065	254	21	high	high	ADJ
admet-3065	254	22	sirna	sirna	PROPN
admet-3065	254	23	delivery	delivery	NOUN
admet-3065	254	24	efficiency	efficiency	NOUN
admet-3065	254	25	.	.	PUNCT
admet-3065	255	1	similarly	similarly	ADV
admet-3065	255	2	,	,	PUNCT
admet-3065	255	3	bhattacharya	bhattacharya	PROPN
admet-3065	255	4	’s	’s	PART
admet-3065	255	5	group	group	NOUN
admet-3065	255	6	developed	develop	VERB
admet-3065	255	7	gemini	gemini	NOUN
admet-3065	255	8	-	-	PUNCT
admet-3065	255	9	type	type	NOUN
admet-3065	255	10	cholesterol	cholesterol	NOUN
admet-3065	255	11	-	-	PUNCT
admet-3065	255	12	derived	derive	VERB
admet-3065	255	13	cationic	cationic	ADJ
admet-3065	255	14	surfactants	surfactant	NOUN
admet-3065	255	15	with	with	ADP
admet-3065	255	16	transfection	transfection	NOUN
admet-3065	255	17	efficiencies	efficiency	NOUN
admet-3065	255	18	comparable	comparable	ADJ
admet-3065	255	19	to	to	ADP
admet-3065	255	20	single	single	ADJ
admet-3065	255	21	-	-	PUNCT
admet-3065	255	22	tailed	tail	VERB
admet-3065	255	23	counterparts	counterpart	NOUN
admet-3065	255	24	and	and	CCONJ
admet-3065	255	25	lipofectamine	lipofectamine	NOUN
admet-3065	255	26	[	[	X
admet-3065	255	27	132	132	NUM
admet-3065	255	28	]	]	PUNCT
admet-3065	255	29	.	.	PUNCT
admet-3065	256	1	beyond	beyond	ADP
admet-3065	256	2	cholesterol	cholesterol	NOUN
admet-3065	256	3	,	,	PUNCT
admet-3065	256	4	other	other	ADJ
admet-3065	256	5	steroid	steroid	NOUN
admet-3065	256	6	-	-	PUNCT
admet-3065	256	7	based	base	VERB
admet-3065	256	8	scaffolds	scaffold	NOUN
admet-3065	256	9	,	,	PUNCT
admet-3065	256	10	including	include	VERB
admet-3065	256	11	vitamins	vitamin	NOUN
admet-3065	256	12	,	,	PUNCT
admet-3065	256	13	bile	bile	NOUN
admet-3065	256	14	acids	acid	NOUN
admet-3065	256	15	,	,	PUNCT
admet-3065	256	16	cholestane	cholestane	NOUN
admet-3065	256	17	,	,	PUNCT
admet-3065	256	18	and	and	CCONJ
admet-3065	256	19	lithocholic	lithocholic	ADJ
admet-3065	256	20	acid	acid	NOUN
admet-3065	256	21	,	,	PUNCT
admet-3065	256	22	have	have	AUX
admet-3065	256	23	shown	show	VERB
admet-3065	256	24	potential	potential	NOUN
admet-3065	256	25	.	.	PUNCT
admet-3065	257	1	vitamin	vitamin	NOUN
admet-3065	257	2	d₂	d₂	NOUN
admet-3065	257	3	and	and	CCONJ
admet-3065	257	4	d₃	d₃	PROPN
admet-3065	257	5	analogues	analogue	NOUN
admet-3065	257	6	have	have	AUX
admet-3065	257	7	yielded	yield	VERB
admet-3065	257	8	transfection	transfection	NOUN
admet-3065	257	9	agents	agent	NOUN
admet-3065	257	10	comparable	comparable	ADJ
admet-3065	257	11	to	to	ADP
admet-3065	257	12	dc	dc	PROPN
admet-3065	257	13	-	-	PUNCT
admet-3065	257	14	chol	chol	NOUN
admet-3065	257	15	[	[	X
admet-3065	257	16	133	133	NUM
admet-3065	257	17	]	]	PUNCT
admet-3065	257	18	,	,	PUNCT
admet-3065	257	19	while	while	SCONJ
admet-3065	257	20	α	α	X
admet-3065	257	21	-	-	NOUN
admet-3065	257	22	tocopherol	tocopherol	NOUN
admet-3065	257	23	(	(	PUNCT
admet-3065	257	24	vitamin	vitamin	NOUN
admet-3065	257	25	e)-based	e)-base	VERB
admet-3065	257	26	lipids	lipid	NOUN
admet-3065	257	27	have	have	AUX
admet-3065	257	28	demonstrated	demonstrate	VERB
admet-3065	257	29	enhanced	enhanced	ADJ
admet-3065	257	30	transfection	transfection	NOUN
admet-3065	257	31	activity	activity	NOUN
admet-3065	257	32	.	.	PUNCT
admet-3065	258	1	bile	bile	NOUN
admet-3065	258	2	acid	acid	NOUN
admet-3065	258	3	-	-	PUNCT
admet-3065	258	4	based	base	VERB
admet-3065	258	5	lipids	lipid	NOUN
admet-3065	258	6	have	have	AUX
admet-3065	258	7	also	also	ADV
admet-3065	258	8	achieved	achieve	VERB
admet-3065	258	9	success	success	NOUN
admet-3065	258	10	in	in	ADP
admet-3065	258	11	gene	gene	NOUN
admet-3065	258	12	delivery	delivery	NOUN
admet-3065	258	13	systems	system	NOUN
admet-3065	258	14	,	,	PUNCT
admet-3065	258	15	albeit	albeit	SCONJ
admet-3065	258	16	to	to	ADP
admet-3065	258	17	a	a	DET
admet-3065	258	18	lesser	less	ADJ
admet-3065	258	19	extent	extent	NOUN
admet-3065	258	20	[	[	X
admet-3065	258	21	134	134	NUM
admet-3065	258	22	]	]	PUNCT
admet-3065	258	23	.	.	PUNCT
admet-3065	259	1	collectively	collectively	ADV
admet-3065	259	2	,	,	PUNCT
admet-3065	259	3	these	these	DET
admet-3065	259	4	findings	finding	NOUN
admet-3065	259	5	highlight	highlight	VERB
admet-3065	259	6	the	the	DET
admet-3065	259	7	importance	importance	NOUN
admet-3065	259	8	of	of	ADP
admet-3065	259	9	aliphatic	aliphatic	ADJ
admet-3065	259	10	and	and	CCONJ
admet-3065	259	11	steroid	steroid	NOUN
admet-3065	259	12	-	-	PUNCT
admet-3065	259	13	based	base	VERB
admet-3065	259	14	hydrophobic	hydrophobic	NOUN
admet-3065	259	15	domains	domain	NOUN
admet-3065	259	16	in	in	ADP
admet-3065	259	17	designing	design	VERB
admet-3065	259	18	effective	effective	ADJ
admet-3065	259	19	cationic	cationic	ADJ
admet-3065	259	20	lipid	lipid	NOUN
admet-3065	259	21	transfectants	transfectant	NOUN
admet-3065	259	22	.	.	PUNCT
admet-3065	260	1	single	single	ADJ
admet-3065	260	2	-	-	PUNCT
admet-3065	260	3	tailed	tail	VERB
admet-3065	260	4	cholesterol	cholesterol	NOUN
admet-3065	260	5	-	-	PUNCT
admet-3065	260	6	based	base	VERB
admet-3065	260	7	lipids	lipid	NOUN
admet-3065	260	8	and	and	CCONJ
admet-3065	260	9	double	double	ADJ
admet-3065	260	10	-	-	PUNCT
admet-3065	260	11	tailed	tail	VERB
admet-3065	260	12	monounsaturated	monounsaturate	VERB
admet-3065	260	13	aliphatic	aliphatic	ADJ
admet-3065	260	14	lipids	lipid	NOUN
admet-3065	260	15	consistently	consistently	ADV
admet-3065	260	16	emerge	emerge	VERB
admet-3065	260	17	as	as	ADP
admet-3065	260	18	highly	highly	ADV
admet-3065	260	19	promising	promising	ADJ
admet-3065	260	20	lipophilic	lipophilic	ADJ
admet-3065	260	21	motifs	motif	NOUN
admet-3065	260	22	for	for	ADP
admet-3065	260	23	gene	gene	NOUN
admet-3065	260	24	delivery	delivery	NOUN
admet-3065	260	25	(	(	PUNCT
admet-3065	260	26	table	table	NOUN
admet-3065	260	27	5	5	NUM
admet-3065	260	28	)	)	PUNCT
admet-3065	260	29	.	.	PUNCT
admet-3065	261	1	table	table	NOUN
admet-3065	261	2	5	5	NUM
admet-3065	261	3	.	.	PUNCT
admet-3065	262	1	overview	overview	NOUN
admet-3065	262	2	of	of	ADP
admet-3065	262	3	hydrophobic	hydrophobic	NOUN
admet-3065	262	4	tail	tail	NOUN
admet-3065	262	5	types	type	NOUN
admet-3065	262	6	and	and	CCONJ
admet-3065	262	7	their	their	PRON
admet-3065	262	8	roles	role	NOUN
admet-3065	262	9	in	in	ADP
admet-3065	262	10	cationic	cationic	ADJ
admet-3065	262	11	lipid	lipid	NOUN
admet-3065	262	12	design	design	NOUN
admet-3065	262	13	tail	tail	NOUN
admet-3065	262	14	type	type	NOUN
admet-3065	262	15	structure	structure	NOUN
admet-3065	262	16	role	role	NOUN
admet-3065	262	17	key	key	NOUN
admet-3065	262	18	features	feature	VERB
admet-3065	262	19	transfection	transfection	NOUN
admet-3065	262	20	effect	effect	NOUN
admet-3065	262	21	aliphatic	aliphatic	ADJ
admet-3065	262	22	chains	chain	NOUN
admet-3065	262	23	saturated	saturate	VERB
admet-3065	262	24	/	/	SYM
admet-3065	262	25	unsaturated	unsaturate	VERB
admet-3065	262	26	c14	c14	NOUN
admet-3065	262	27	-	-	PUNCT
admet-3065	262	28	c18	c18	NOUN
admet-3065	262	29	membrane	membrane	NOUN
admet-3065	262	30	fluidity	fluidity	NOUN
admet-3065	262	31	,	,	PUNCT
admet-3065	262	32	fusion	fusion	NOUN
admet-3065	262	33	double	double	ADJ
admet-3065	262	34	tails	tail	NOUN
admet-3065	262	35	improve	improve	VERB
admet-3065	262	36	stability	stability	NOUN
admet-3065	262	37	c14	c14	NOUN
admet-3065	262	38	-	-	PUNCT
admet-3065	262	39	c18	c18	NOUN
admet-3065	262	40	monounsaturated	monounsaturate	VERB
admet-3065	262	41	are	be	AUX
admet-3065	262	42	optimal	optimal	ADJ
admet-3065	262	43	cyclic	cyclic	ADJ
admet-3065	262	44	(	(	PUNCT
admet-3065	262	45	steroidal	steroidal	NOUN
admet-3065	262	46	)	)	PUNCT
admet-3065	262	47	cholesterol	cholesterol	NOUN
admet-3065	262	48	,	,	PUNCT
admet-3065	262	49	bile	bile	NOUN
admet-3065	262	50	acids	acid	NOUN
admet-3065	262	51	rigidity	rigidity	NOUN
admet-3065	262	52	,	,	PUNCT
admet-3065	262	53	biocompatibility	biocompatibility	NOUN
admet-3065	262	54	enhances	enhance	VERB
admet-3065	262	55	endosomal	endosomal	ADJ
admet-3065	262	56	escape	escape	VERB
admet-3065	262	57	dc	dc	PROPN
admet-3065	262	58	-	-	PUNCT
admet-3065	262	59	chol	chol	NOUN
admet-3065	262	60	widely	widely	ADV
admet-3065	262	61	used	use	VERB
admet-3065	262	62	tail	tail	NOUN
admet-3065	262	63	number	number	NOUN
admet-3065	262	64	single	single	ADJ
admet-3065	262	65	/	/	SYM
admet-3065	262	66	double	double	ADJ
admet-3065	262	67	/	/	SYM
admet-3065	262	68	multi	multi	ADJ
admet-3065	262	69	-	-	ADJ
admet-3065	262	70	tail	tail	ADJ
admet-3065	262	71	aggregation	aggregation	NOUN
admet-3065	262	72	behaviour	behaviour	NOUN
admet-3065	262	73	double	double	ADJ
admet-3065	262	74	-	-	PUNCT
admet-3065	262	75	tail	tail	NOUN
admet-3065	262	76	>	>	PUNCT
admet-3065	262	77	single	single	ADJ
admet-3065	262	78	-	-	PUNCT
admet-3065	262	79	tail	tail	NOUN
admet-3065	262	80	stability	stability	NOUN
admet-3065	262	81	and	and	CCONJ
admet-3065	262	82	dna	dna	NOUN
admet-3065	262	83	condensation	condensation	NOUN
admet-3065	262	84	admet	admet	NOUN
admet-3065	262	85	&	&	CCONJ
admet-3065	262	86	dmpk	dmpk	PROPN
admet-3065	262	87	00(0	00(0	PROPN
admet-3065	262	88	)	)	PUNCT
admet-3065	262	89	(	(	PUNCT
admet-3065	262	90	2025	2025	NUM
admet-3065	262	91	)	)	PUNCT
admet-3065	262	92	3065	3065	NUM
admet-3065	262	93	liposome	liposome	NOUN
admet-3065	262	94	-	-	PUNCT
admet-3065	262	95	mediated	mediate	VERB
admet-3065	262	96	gene	gene	NOUN
admet-3065	262	97	delivery	delivery	NOUN
admet-3065	262	98	doi	doi	NOUN
admet-3065	262	99	:	:	PUNCT
admet-3065	262	100	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	262	101	13	13	NUM
admet-3065	262	102	helper	helper	NOUN
admet-3065	262	103	lipids	lipids	ADP
admet-3065	262	104	the	the	DET
admet-3065	262	105	efficacy	efficacy	NOUN
admet-3065	262	106	of	of	ADP
admet-3065	262	107	cationic	cationic	ADJ
admet-3065	262	108	lipids	lipid	NOUN
admet-3065	262	109	in	in	ADP
admet-3065	262	110	nucleic	nucleic	ADJ
admet-3065	262	111	acid	acid	NOUN
admet-3065	262	112	(	(	PUNCT
admet-3065	262	113	na	na	NOUN
admet-3065	262	114	)	)	PUNCT
admet-3065	262	115	delivery	delivery	NOUN
admet-3065	262	116	is	be	AUX
admet-3065	262	117	significantly	significantly	ADV
admet-3065	262	118	enhanced	enhance	VERB
admet-3065	262	119	when	when	SCONJ
admet-3065	262	120	co	co	VERB
admet-3065	262	121	-	-	VERB
admet-3065	262	122	formulated	formulate	VERB
admet-3065	262	123	with	with	ADP
admet-3065	262	124	zwitterionic	zwitterionic	ADJ
admet-3065	262	125	helper	helper	NOUN
admet-3065	262	126	lipids	lipid	NOUN
admet-3065	262	127	,	,	PUNCT
admet-3065	262	128	such	such	ADJ
admet-3065	262	129	as	as	ADP
admet-3065	262	130	1,2	1,2	NUM
admet-3065	262	131	-	-	PUNCT
admet-3065	262	132	dioleoyl	dioleoyl	ADJ
admet-3065	262	133	-	-	PUNCT
admet-3065	262	134	sn	sn	NOUN
admet-3065	262	135	-	-	PUNCT
admet-3065	262	136	glycero-3	glycero-3	NOUN
admet-3065	262	137	-	-	PUNCT
admet-3065	262	138	phosphoethanolamine	phosphoethanolamine	NOUN
admet-3065	262	139	(	(	PUNCT
admet-3065	262	140	dope	dope	NOUN
admet-3065	262	141	)	)	PUNCT
admet-3065	262	142	or	or	CCONJ
admet-3065	262	143	1,2	1,2	NUM
admet-3065	262	144	-	-	PUNCT
admet-3065	262	145	dioleoyl	dioleoyl	ADJ
admet-3065	262	146	-	-	PUNCT
admet-3065	262	147	sn	sn	NOUN
admet-3065	262	148	-	-	PUNCT
admet-3065	262	149	glycero-3	glycero-3	NOUN
admet-3065	262	150	-	-	PUNCT
admet-3065	262	151	phosphocholine	phosphocholine	NOUN
admet-3065	262	152	(	(	PUNCT
admet-3065	262	153	dopc	dopc	NOUN
admet-3065	262	154	)	)	PUNCT
admet-3065	262	155	.	.	PUNCT
admet-3065	263	1	these	these	DET
admet-3065	263	2	co	co	ADJ
admet-3065	263	3	-	-	ADJ
admet-3065	263	4	lipids	lipids	ADJ
admet-3065	263	5	promote	promote	VERB
admet-3065	263	6	the	the	DET
admet-3065	263	7	assembly	assembly	NOUN
admet-3065	263	8	of	of	ADP
admet-3065	263	9	supramolecular	supramolecular	ADJ
admet-3065	263	10	structures	structure	NOUN
admet-3065	263	11	,	,	PUNCT
admet-3065	263	12	improving	improve	VERB
admet-3065	263	13	lipoplex	lipoplex	NOUN
admet-3065	263	14	colloidal	colloidal	NOUN
admet-3065	263	15	stability	stability	NOUN
admet-3065	263	16	and	and	CCONJ
admet-3065	263	17	enhancing	enhance	VERB
admet-3065	263	18	interactions	interaction	NOUN
admet-3065	263	19	with	with	ADP
admet-3065	263	20	cellular	cellular	ADJ
admet-3065	263	21	membranes	membrane	NOUN
admet-3065	263	22	[	[	X
admet-3065	263	23	135	135	NUM
admet-3065	263	24	]	]	PUNCT
admet-3065	263	25	.	.	PUNCT
admet-3065	264	1	dope	dope	NOUN
admet-3065	264	2	’s	’s	PART
admet-3065	264	3	structure	structure	NOUN
admet-3065	264	4	,	,	PUNCT
admet-3065	264	5	featuring	feature	VERB
admet-3065	264	6	a	a	DET
admet-3065	264	7	compact	compact	ADJ
admet-3065	264	8	phosphoethanolamine	phosphoethanolamine	NOUN
admet-3065	264	9	headgroup	headgroup	NOUN
admet-3065	264	10	linked	link	VERB
admet-3065	264	11	via	via	ADP
admet-3065	264	12	ester	ester	NOUN
admet-3065	264	13	bonds	bond	NOUN
admet-3065	264	14	to	to	ADP
admet-3065	264	15	two	two	NUM
admet-3065	264	16	unsaturated	unsaturated	ADJ
admet-3065	264	17	oleyl	oleyl	ADJ
admet-3065	264	18	chains	chain	NOUN
admet-3065	264	19	,	,	PUNCT
admet-3065	264	20	imparts	impart	VERB
admet-3065	264	21	fusogenic	fusogenic	ADJ
admet-3065	264	22	properties	property	NOUN
admet-3065	264	23	that	that	PRON
admet-3065	264	24	facilitate	facilitate	VERB
admet-3065	264	25	endosomal	endosomal	ADJ
admet-3065	264	26	escape	escape	NOUN
admet-3065	264	27	.	.	PUNCT
admet-3065	265	1	in	in	ADP
admet-3065	265	2	acidic	acidic	ADJ
admet-3065	265	3	environments	environment	NOUN
admet-3065	265	4	(	(	PUNCT
admet-3065	265	5	ph	ph	NOUN
admet-3065	265	6	4	4	NUM
admet-3065	265	7	-	-	SYM
admet-3065	265	8	5	5	NUM
admet-3065	265	9	)	)	PUNCT
admet-3065	265	10	,	,	PUNCT
admet-3065	265	11	dope	dope	NOUN
admet-3065	265	12	-	-	PUNCT
admet-3065	265	13	containing	contain	VERB
admet-3065	265	14	lipoplexes	lipoplexe	NOUN
admet-3065	265	15	undergo	undergo	VERB
admet-3065	265	16	conformational	conformational	ADJ
admet-3065	265	17	changes	change	NOUN
admet-3065	265	18	that	that	PRON
admet-3065	265	19	destabilize	destabilize	VERB
admet-3065	265	20	the	the	DET
admet-3065	265	21	complex	complex	NOUN
admet-3065	265	22	,	,	PUNCT
admet-3065	265	23	promoting	promote	VERB
admet-3065	265	24	na	na	PART
admet-3065	265	25	release	release	VERB
admet-3065	265	26	[	[	X
admet-3065	265	27	136,137	136,137	NUM
admet-3065	265	28	]	]	PUNCT
admet-3065	265	29	.	.	PUNCT
admet-3065	266	1	these	these	DET
admet-3065	266	2	attributes	attribute	NOUN
admet-3065	266	3	have	have	AUX
admet-3065	266	4	made	make	VERB
admet-3065	266	5	dope	dope	NOUN
admet-3065	266	6	a	a	DET
admet-3065	266	7	key	key	ADJ
admet-3065	266	8	component	component	NOUN
admet-3065	266	9	in	in	ADP
admet-3065	266	10	commercial	commercial	ADJ
admet-3065	266	11	transfection	transfection	NOUN
admet-3065	266	12	reagents	reagent	NOUN
admet-3065	266	13	,	,	PUNCT
admet-3065	266	14	such	such	ADJ
admet-3065	266	15	as	as	ADP
admet-3065	266	16	lipofectin	lipofectin	NOUN
admet-3065	266	17	(	(	PUNCT
admet-3065	266	18	dotma	dotma	NOUN
admet-3065	266	19	:	:	PUNCT
admet-3065	266	20	dope	dope	NOUN
admet-3065	266	21	,	,	PUNCT
admet-3065	266	22	1:1	1:1	NUM
admet-3065	266	23	weight	weight	NOUN
admet-3065	266	24	ratio	ratio	NOUN
admet-3065	266	25	)	)	PUNCT
admet-3065	266	26	and	and	CCONJ
admet-3065	266	27	lipofectamine	lipofectamine	NOUN
admet-3065	266	28	(	(	PUNCT
admet-3065	266	29	dospa	dospa	NOUN
admet-3065	266	30	:	:	PUNCT
admet-3065	266	31	dope	dope	NOUN
admet-3065	266	32	,	,	PUNCT
admet-3065	266	33	3:1	3:1	NUM
admet-3065	266	34	weight	weight	NOUN
admet-3065	266	35	ratio	ratio	NOUN
admet-3065	266	36	)	)	PUNCT
admet-3065	267	1	[	[	X
admet-3065	267	2	138	138	NUM
admet-3065	267	3	]	]	PUNCT
admet-3065	267	4	.	.	PUNCT
admet-3065	268	1	in	in	ADP
admet-3065	268	2	contrast	contrast	NOUN
admet-3065	268	3	,	,	PUNCT
admet-3065	268	4	dopc	dopc	NOUN
admet-3065	268	5	’s	’s	PART
admet-3065	268	6	zwitterionic	zwitterionic	ADJ
admet-3065	268	7	structure	structure	NOUN
admet-3065	268	8	,	,	PUNCT
admet-3065	268	9	with	with	ADP
admet-3065	268	10	both	both	CCONJ
admet-3065	268	11	an	an	DET
admet-3065	268	12	anionic	anionic	ADJ
admet-3065	268	13	phosphate	phosphate	NOUN
admet-3065	268	14	and	and	CCONJ
admet-3065	268	15	a	a	DET
admet-3065	268	16	cationic	cationic	ADJ
admet-3065	268	17	choline	choline	NOUN
admet-3065	268	18	group	group	NOUN
admet-3065	268	19	,	,	PUNCT
admet-3065	268	20	forms	form	VERB
admet-3065	268	21	more	more	ADV
admet-3065	268	22	stable	stable	ADJ
admet-3065	268	23	lipoplex	lipoplex	NOUN
admet-3065	268	24	complexes	complex	NOUN
admet-3065	268	25	but	but	CCONJ
admet-3065	268	26	exhibits	exhibit	VERB
admet-3065	268	27	lower	low	ADJ
admet-3065	268	28	transfection	transfection	NOUN
admet-3065	268	29	efficiency	efficiency	NOUN
admet-3065	268	30	compared	compare	VERB
admet-3065	268	31	to	to	ADP
admet-3065	268	32	dope	dope	NOUN
admet-3065	268	33	-	-	PUNCT
admet-3065	268	34	based	base	VERB
admet-3065	268	35	systems	system	NOUN
admet-3065	268	36	[	[	X
admet-3065	268	37	139	139	NUM
admet-3065	268	38	]	]	PUNCT
admet-3065	268	39	.	.	PUNCT
admet-3065	269	1	comparative	comparative	ADJ
admet-3065	269	2	studies	study	NOUN
admet-3065	269	3	demonstrate	demonstrate	VERB
admet-3065	269	4	that	that	SCONJ
admet-3065	269	5	dope	dope	NOUN
admet-3065	269	6	formulations	formulation	NOUN
admet-3065	269	7	enable	enable	VERB
admet-3065	269	8	faster	fast	ADJ
admet-3065	269	9	endosomal	endosomal	ADJ
admet-3065	269	10	trafficking	trafficking	NOUN
admet-3065	269	11	and	and	CCONJ
admet-3065	269	12	nucleus	nucleus	ADJ
admet-3065	269	13	delivery	delivery	NOUN
admet-3065	269	14	of	of	ADP
admet-3065	269	15	dna	dna	PROPN
admet-3065	269	16	,	,	PUNCT
admet-3065	269	17	whereas	whereas	SCONJ
admet-3065	269	18	dopc	dopc	NOUN
admet-3065	269	19	-	-	PUNCT
admet-3065	269	20	based	base	VERB
admet-3065	269	21	lipoplexes	lipoplexe	NOUN
admet-3065	269	22	are	be	AUX
admet-3065	269	23	often	often	ADV
admet-3065	269	24	retained	retain	VERB
admet-3065	269	25	in	in	ADP
admet-3065	269	26	late	late	ADJ
admet-3065	269	27	endolysosomes	endolysosome	NOUN
admet-3065	269	28	,	,	PUNCT
admet-3065	269	29	limiting	limit	VERB
admet-3065	269	30	their	their	PRON
admet-3065	269	31	efficacy	efficacy	NOUN
admet-3065	269	32	[	[	X
admet-3065	269	33	140	140	NUM
admet-3065	269	34	]	]	PUNCT
admet-3065	269	35	.	.	PUNCT
admet-3065	270	1	cholesterol	cholesterol	PROPN
admet-3065	270	2	,	,	PUNCT
admet-3065	270	3	a	a	DET
admet-3065	270	4	neutral	neutral	ADJ
admet-3065	270	5	amphiphile	amphiphile	NOUN
admet-3065	270	6	,	,	PUNCT
admet-3065	270	7	is	be	AUX
admet-3065	270	8	another	another	DET
admet-3065	270	9	critical	critical	ADJ
admet-3065	270	10	helper	helper	NOUN
admet-3065	270	11	lipid	lipid	NOUN
admet-3065	270	12	that	that	PRON
admet-3065	270	13	enhances	enhance	VERB
admet-3065	270	14	lipoplex	lipoplex	PROPN
admet-3065	270	15	function	function	NOUN
admet-3065	270	16	through	through	ADP
admet-3065	270	17	distinct	distinct	ADJ
admet-3065	270	18	mechanisms	mechanism	NOUN
admet-3065	270	19	.	.	PUNCT
admet-3065	271	1	cholesterol	cholesterol	NOUN
admet-3065	271	2	promotes	promote	VERB
admet-3065	271	3	membrane	membrane	NOUN
admet-3065	271	4	packing	packing	NOUN
admet-3065	271	5	and	and	CCONJ
admet-3065	271	6	structural	structural	ADJ
admet-3065	271	7	stability	stability	NOUN
admet-3065	271	8	without	without	ADP
admet-3065	271	9	directly	directly	ADV
admet-3065	271	10	interacting	interact	VERB
admet-3065	271	11	with	with	ADP
admet-3065	271	12	nas	nas	PROPN
admet-3065	271	13	.	.	PUNCT
admet-3065	272	1	its	its	PRON
admet-3065	272	2	incorporation	incorporation	NOUN
admet-3065	272	3	into	into	ADP
admet-3065	272	4	lipoplex	lipoplex	NOUN
admet-3065	272	5	formulations	formulation	NOUN
admet-3065	272	6	enhances	enhance	VERB
admet-3065	272	7	interactions	interaction	NOUN
admet-3065	272	8	with	with	ADP
admet-3065	272	9	plasma	plasma	NOUN
admet-3065	272	10	and	and	CCONJ
admet-3065	272	11	endosomal	endosomal	ADJ
admet-3065	272	12	membranes	membrane	NOUN
admet-3065	272	13	,	,	PUNCT
admet-3065	272	14	thereby	thereby	ADV
admet-3065	272	15	improving	improve	VERB
admet-3065	272	16	transfection	transfection	NOUN
admet-3065	272	17	efficiency	efficiency	NOUN
admet-3065	272	18	[	[	X
admet-3065	272	19	140	140	NUM
admet-3065	272	20	]	]	PUNCT
admet-3065	272	21	.	.	PUNCT
admet-3065	273	1	collectively	collectively	ADV
admet-3065	273	2	,	,	PUNCT
admet-3065	273	3	these	these	DET
admet-3065	273	4	findings	finding	NOUN
admet-3065	273	5	underscore	underscore	VERB
admet-3065	273	6	the	the	DET
admet-3065	273	7	pivotal	pivotal	ADJ
admet-3065	273	8	role	role	NOUN
admet-3065	273	9	of	of	ADP
admet-3065	273	10	helper	helper	NOUN
admet-3065	273	11	lipids	lipid	NOUN
admet-3065	273	12	in	in	ADP
admet-3065	273	13	optimizing	optimize	VERB
admet-3065	273	14	gene	gene	NOUN
admet-3065	273	15	delivery	delivery	NOUN
admet-3065	273	16	systems	system	NOUN
admet-3065	273	17	.	.	PUNCT
admet-3065	274	1	dope	dope	NOUN
admet-3065	274	2	and	and	CCONJ
admet-3065	274	3	cholesterol	cholesterol	NOUN
admet-3065	274	4	remain	remain	VERB
admet-3065	274	5	the	the	DET
admet-3065	274	6	most	most	ADV
admet-3065	274	7	widely	widely	ADV
admet-3065	274	8	used	use	VERB
admet-3065	274	9	due	due	ADP
admet-3065	274	10	to	to	ADP
admet-3065	274	11	their	their	PRON
admet-3065	274	12	favourable	favourable	ADJ
admet-3065	274	13	membrane	membrane	NOUN
admet-3065	274	14	interaction	interaction	NOUN
admet-3065	274	15	properties	property	NOUN
admet-3065	274	16	,	,	PUNCT
admet-3065	274	17	while	while	SCONJ
admet-3065	274	18	ongoing	ongoing	ADJ
admet-3065	274	19	research	research	NOUN
admet-3065	274	20	continues	continue	VERB
admet-3065	274	21	to	to	PART
admet-3065	274	22	explore	explore	VERB
admet-3065	274	23	optimal	optimal	ADJ
admet-3065	274	24	co	co	ADJ
admet-3065	274	25	-	-	NOUN
admet-3065	274	26	lipid	lipid	ADJ
admet-3065	274	27	combinations	combination	NOUN
admet-3065	274	28	and	and	CCONJ
admet-3065	274	29	innovative	innovative	ADJ
admet-3065	274	30	designs	design	NOUN
admet-3065	274	31	to	to	PART
admet-3065	274	32	further	far	ADV
admet-3065	274	33	enhance	enhance	VERB
admet-3065	274	34	transfection	transfection	NOUN
admet-3065	274	35	efficiency	efficiency	NOUN
admet-3065	274	36	.	.	PUNCT
admet-3065	275	1	biophysical	biophysical	ADJ
admet-3065	275	2	parameters	parameter	NOUN
admet-3065	275	3	influencing	influence	VERB
admet-3065	275	4	gene	gene	NOUN
admet-3065	275	5	delivery	delivery	NOUN
admet-3065	275	6	liposome	liposome	NOUN
admet-3065	275	7	size	size	NOUN
admet-3065	275	8	the	the	DET
admet-3065	275	9	size	size	NOUN
admet-3065	275	10	of	of	ADP
admet-3065	275	11	the	the	DET
admet-3065	275	12	liposomes	liposome	NOUN
admet-3065	275	13	is	be	AUX
admet-3065	275	14	a	a	DET
admet-3065	275	15	factor	factor	NOUN
admet-3065	275	16	in	in	ADP
admet-3065	275	17	drug	drug	NOUN
admet-3065	275	18	delivery	delivery	NOUN
admet-3065	275	19	.	.	PUNCT
admet-3065	276	1	it	it	PRON
admet-3065	276	2	directly	directly	ADV
admet-3065	276	3	influences	influence	VERB
admet-3065	276	4	the	the	DET
admet-3065	276	5	duration	duration	NOUN
admet-3065	276	6	they	they	PRON
admet-3065	276	7	remain	remain	VERB
admet-3065	276	8	in	in	ADP
admet-3065	276	9	the	the	DET
admet-3065	276	10	bloodstream	bloodstream	NOUN
admet-3065	276	11	,	,	PUNCT
admet-3065	276	12	as	as	SCONJ
admet-3065	276	13	nanoparticles	nanoparticle	NOUN
admet-3065	276	14	and	and	CCONJ
admet-3065	276	15	macromolecules	macromolecule	NOUN
admet-3065	276	16	are	be	AUX
admet-3065	276	17	removed	remove	VERB
admet-3065	276	18	by	by	ADP
admet-3065	276	19	the	the	DET
admet-3065	276	20	renal	renal	ADJ
admet-3065	276	21	system	system	NOUN
admet-3065	276	22	and	and	CCONJ
admet-3065	276	23	the	the	DET
admet-3065	276	24	mononuclear	mononuclear	ADJ
admet-3065	276	25	phagocytic	phagocytic	ADJ
admet-3065	276	26	system	system	NOUN
admet-3065	276	27	(	(	PUNCT
admet-3065	276	28	mps	mps	PROPN
admet-3065	276	29	)	)	PUNCT
admet-3065	277	1	[	[	X
admet-3065	277	2	141,142	141,142	NUM
admet-3065	277	3	]	]	PUNCT
admet-3065	277	4	.	.	PUNCT
admet-3065	277	5	nanoparticles	nanoparticle	NOUN
admet-3065	277	6	smaller	small	ADJ
admet-3065	277	7	than	than	ADP
admet-3065	277	8	10	10	NUM
admet-3065	277	9	nm	nm	NOUN
admet-3065	277	10	are	be	AUX
admet-3065	277	11	rapidly	rapidly	ADV
admet-3065	277	12	excreted	excrete	VERB
admet-3065	277	13	by	by	ADP
admet-3065	277	14	the	the	DET
admet-3065	277	15	kidneys	kidney	NOUN
admet-3065	277	16	,	,	PUNCT
admet-3065	277	17	while	while	SCONJ
admet-3065	277	18	bigger	big	ADJ
admet-3065	277	19	particles	particle	NOUN
admet-3065	277	20	are	be	AUX
admet-3065	277	21	predominantly	predominantly	ADV
admet-3065	277	22	eliminated	eliminate	VERB
admet-3065	277	23	by	by	ADP
admet-3065	277	24	the	the	DET
admet-3065	277	25	mps	mp	NOUN
admet-3065	278	1	[	[	X
admet-3065	278	2	142	142	NUM
admet-3065	278	3	]	]	PUNCT
admet-3065	278	4	.	.	PUNCT
admet-3065	279	1	tumours	tumours	PROPN
admet-3065	279	2	,	,	PUNCT
admet-3065	279	3	in	in	ADP
admet-3065	279	4	contrast	contrast	NOUN
admet-3065	279	5	,	,	PUNCT
admet-3065	279	6	exhibit	exhibit	VERB
admet-3065	279	7	leaky	leaky	ADJ
admet-3065	279	8	vasculature	vasculature	NOUN
admet-3065	279	9	with	with	ADP
admet-3065	279	10	widened	widen	VERB
admet-3065	279	11	endothelial	endothelial	ADJ
admet-3065	279	12	pores	pore	NOUN
admet-3065	279	13	that	that	PRON
admet-3065	279	14	enable	enable	VERB
admet-3065	279	15	nanoparticles	nanoparticle	NOUN
admet-3065	279	16	of	of	ADP
admet-3065	279	17	appropriate	appropriate	ADJ
admet-3065	279	18	size	size	NOUN
admet-3065	279	19	to	to	PART
admet-3065	279	20	accumulate	accumulate	VERB
admet-3065	279	21	in	in	ADP
admet-3065	279	22	the	the	DET
admet-3065	279	23	tumour	tumour	NOUN
admet-3065	279	24	tissue	tissue	NOUN
admet-3065	279	25	but	but	CCONJ
admet-3065	279	26	not	not	PART
admet-3065	279	27	normal	normal	ADJ
admet-3065	279	28	organs	organ	NOUN
admet-3065	279	29	,	,	PUNCT
admet-3065	279	30	a	a	DET
admet-3065	279	31	phenomenon	phenomenon	NOUN
admet-3065	279	32	termed	term	VERB
admet-3065	279	33	the	the	DET
admet-3065	279	34	enhanced	enhanced	ADJ
admet-3065	279	35	permeability	permeability	NOUN
admet-3065	279	36	and	and	CCONJ
admet-3065	279	37	retention	retention	NOUN
admet-3065	279	38	(	(	PUNCT
admet-3065	279	39	epr	epr	ADJ
admet-3065	279	40	)	)	PUNCT
admet-3065	279	41	effect	effect	NOUN
admet-3065	280	1	[	[	X
admet-3065	280	2	143,144	143,144	NUM
admet-3065	280	3	]	]	PUNCT
admet-3065	280	4	.	.	PUNCT
admet-3065	281	1	comparative	comparative	ADJ
admet-3065	281	2	research	research	NOUN
admet-3065	281	3	on	on	ADP
admet-3065	281	4	liposomes	liposome	NOUN
admet-3065	281	5	of	of	ADP
admet-3065	281	6	different	different	ADJ
admet-3065	281	7	sizes	size	NOUN
admet-3065	281	8	has	have	AUX
admet-3065	281	9	indicated	indicate	VERB
admet-3065	281	10	that	that	SCONJ
admet-3065	281	11	optimum	optimum	ADJ
admet-3065	281	12	extravasation	extravasation	NOUN
admet-3065	281	13	across	across	ADP
admet-3065	281	14	tumours	tumours	PROPN
admet-3065	281	15	is	be	AUX
admet-3065	281	16	around	around	ADV
admet-3065	281	17	400	400	NUM
admet-3065	281	18	nm	nm	NOUN
admet-3065	281	19	,	,	PUNCT
admet-3065	281	20	whereas	whereas	SCONJ
admet-3065	281	21	particles	particle	NOUN
admet-3065	281	22	smaller	small	ADJ
admet-3065	281	23	than	than	ADP
admet-3065	281	24	200	200	NUM
admet-3065	281	25	nm	nm	NOUN
admet-3065	281	26	are	be	AUX
admet-3065	281	27	better	well	ADJ
admet-3065	281	28	in	in	ADP
admet-3065	281	29	delivering	deliver	VERB
admet-3065	281	30	drugs	drug	NOUN
admet-3065	281	31	[	[	X
admet-3065	281	32	145,146	145,146	NUM
admet-3065	281	33	]	]	PUNCT
admet-3065	281	34	.	.	PUNCT
admet-3065	282	1	liposome	liposome	NOUN
admet-3065	282	2	charge	charge	NOUN
admet-3065	282	3	to	to	PART
admet-3065	282	4	prolong	prolong	VERB
admet-3065	282	5	blood	blood	NOUN
admet-3065	282	6	circulation	circulation	NOUN
admet-3065	282	7	,	,	PUNCT
admet-3065	282	8	zwitterionic	zwitterionic	ADJ
admet-3065	282	9	phosphatidylcholine	phosphatidylcholine	NOUN
admet-3065	282	10	(	(	PUNCT
admet-3065	282	11	pc	pc	NOUN
admet-3065	282	12	)	)	PUNCT
admet-3065	282	13	liposomes	liposome	NOUN
admet-3065	282	14	are	be	AUX
admet-3065	282	15	commonly	commonly	ADV
admet-3065	282	16	used	use	VERB
admet-3065	282	17	to	to	PART
admet-3065	282	18	minimize	minimize	VERB
admet-3065	282	19	protein	protein	NOUN
admet-3065	282	20	binding	bind	VERB
admet-3065	282	21	[	[	X
admet-3065	282	22	147,148	147,148	NUM
admet-3065	282	23	]	]	PUNCT
admet-3065	282	24	.	.	PUNCT
admet-3065	283	1	conversely	conversely	ADV
admet-3065	283	2	,	,	PUNCT
admet-3065	283	3	incorporating	incorporate	VERB
admet-3065	283	4	negatively	negatively	ADV
admet-3065	283	5	charged	charge	VERB
admet-3065	283	6	lipids	lipid	NOUN
admet-3065	283	7	accelerates	accelerate	VERB
admet-3065	283	8	liposome	liposome	VERB
admet-3065	283	9	clearance	clearance	NOUN
admet-3065	283	10	due	due	ADP
admet-3065	283	11	to	to	ADP
admet-3065	283	12	protein	protein	NOUN
admet-3065	283	13	adsorption	adsorption	NOUN
admet-3065	283	14	,	,	PUNCT
admet-3065	283	15	while	while	SCONJ
admet-3065	283	16	cationic	cationic	ADJ
admet-3065	283	17	lipids	lipid	NOUN
admet-3065	283	18	,	,	PUNCT
admet-3065	283	19	typically	typically	ADV
admet-3065	283	20	used	use	VERB
admet-3065	283	21	for	for	ADP
admet-3065	283	22	nucleic	nucleic	ADJ
admet-3065	283	23	acid	acid	NOUN
admet-3065	283	24	delivery	delivery	NOUN
admet-3065	283	25	,	,	PUNCT
admet-3065	283	26	can	can	AUX
admet-3065	283	27	facilitate	facilitate	VERB
admet-3065	283	28	cellular	cellular	ADJ
admet-3065	283	29	uptake	uptake	NOUN
admet-3065	283	30	by	by	ADP
admet-3065	283	31	condensing	condense	VERB
admet-3065	283	32	negatively	negatively	ADV
admet-3065	283	33	charged	charge	VERB
admet-3065	283	34	nucleic	nucleic	ADJ
admet-3065	283	35	acids	acid	NOUN
admet-3065	284	1	[	[	X
admet-3065	284	2	149	149	NUM
admet-3065	284	3	]	]	PUNCT
admet-3065	284	4	.	.	PUNCT
admet-3065	285	1	however	however	ADV
admet-3065	285	2	,	,	PUNCT
admet-3065	285	3	cationic	cationic	ADJ
admet-3065	285	4	lipids	lipid	NOUN
admet-3065	285	5	are	be	AUX
admet-3065	285	6	generally	generally	ADV
admet-3065	285	7	toxic	toxic	ADJ
admet-3065	285	8	to	to	ADP
admet-3065	285	9	cells	cell	NOUN
admet-3065	285	10	and	and	CCONJ
admet-3065	285	11	are	be	AUX
admet-3065	285	12	rapidly	rapidly	ADV
admet-3065	285	13	cleared	clear	VERB
admet-3065	285	14	from	from	ADP
admet-3065	285	15	circulation	circulation	NOUN
admet-3065	285	16	[	[	X
admet-3065	285	17	29	29	NUM
admet-3065	285	18	]	]	PUNCT
admet-3065	285	19	.	.	PUNCT
admet-3065	286	1	cationic	cationic	ADJ
admet-3065	286	2	liposomes	liposome	NOUN
admet-3065	286	3	are	be	AUX
admet-3065	286	4	particularly	particularly	ADV
admet-3065	286	5	effective	effective	ADJ
admet-3065	286	6	for	for	ADP
admet-3065	286	7	delivering	deliver	VERB
admet-3065	286	8	negatively	negatively	ADV
admet-3065	286	9	charged	charge	VERB
admet-3065	286	10	macromolecules	macromolecule	NOUN
admet-3065	286	11	,	,	PUNCT
admet-3065	286	12	such	such	ADJ
admet-3065	286	13	as	as	ADP
admet-3065	286	14	dna	dna	NOUN
admet-3065	286	15	and	and	CCONJ
admet-3065	286	16	rna	rna	PROPN
admet-3065	286	17	,	,	PUNCT
admet-3065	286	18	which	which	PRON
admet-3065	286	19	are	be	AUX
admet-3065	286	20	challenging	challenge	VERB
admet-3065	286	21	to	to	PART
admet-3065	286	22	deliver	deliver	VERB
admet-3065	286	23	passively	passively	ADV
admet-3065	286	24	into	into	ADP
admet-3065	286	25	cells	cell	NOUN
admet-3065	286	26	[	[	X
admet-3065	286	27	150	150	NUM
admet-3065	286	28	]	]	PUNCT
admet-3065	286	29	.	.	PUNCT
admet-3065	287	1	additionally	additionally	ADV
admet-3065	287	2	,	,	PUNCT
admet-3065	287	3	they	they	PRON
admet-3065	287	4	selectively	selectively	ADV
admet-3065	287	5	target	target	VERB
admet-3065	287	6	angiogenic	angiogenic	ADJ
admet-3065	287	7	endothelial	endothelial	ADJ
admet-3065	287	8	cells	cell	NOUN
admet-3065	287	9	in	in	ADP
admet-3065	287	10	tumours	tumour	NOUN
admet-3065	287	11	and	and	CCONJ
admet-3065	287	12	are	be	AUX
admet-3065	288	1	e.	e.	PROPN
admet-3065	288	2	j.	j.	PROPN
admet-3065	288	3	saleh	saleh	PROPN
admet-3065	288	4	et	et	PROPN
admet-3065	288	5	al	al	PROPN
admet-3065	288	6	.	.	PROPN
admet-3065	288	7	admet	admet	PROPN
admet-3065	288	8	&	&	CCONJ
admet-3065	288	9	dmpk	dmpk	PROPN
admet-3065	288	10	00(0	00(0	PROPN
admet-3065	288	11	)	)	PUNCT
admet-3065	288	12	(	(	PUNCT
admet-3065	288	13	2025	2025	NUM
admet-3065	288	14	)	)	PUNCT
admet-3065	288	15	3065	3065	NUM
admet-3065	288	16	14	14	NUM
admet-3065	288	17	considered	consider	VERB
admet-3065	288	18	a	a	DET
admet-3065	288	19	promising	promising	ADJ
admet-3065	288	20	tool	tool	NOUN
admet-3065	288	21	for	for	ADP
admet-3065	288	22	brain	brain	NOUN
admet-3065	288	23	drug	drug	NOUN
admet-3065	288	24	delivery	delivery	NOUN
admet-3065	288	25	as	as	SCONJ
admet-3065	288	26	they	they	PRON
admet-3065	288	27	can	can	AUX
admet-3065	288	28	cross	cross	VERB
admet-3065	288	29	the	the	DET
admet-3065	288	30	blood	blood	NOUN
admet-3065	288	31	-	-	PUNCT
admet-3065	288	32	brain	brain	NOUN
admet-3065	288	33	barrier	barrier	NOUN
admet-3065	288	34	(	(	PUNCT
admet-3065	288	35	bbb	bbb	NOUN
admet-3065	288	36	)	)	PUNCT
admet-3065	289	1	[	[	X
admet-3065	289	2	151	151	NUM
admet-3065	289	3	]	]	PUNCT
admet-3065	289	4	.	.	PUNCT
admet-3065	290	1	however	however	ADV
admet-3065	290	2	,	,	PUNCT
admet-3065	290	3	the	the	DET
admet-3065	290	4	positive	positive	ADJ
admet-3065	290	5	charge	charge	NOUN
admet-3065	290	6	can	can	AUX
admet-3065	290	7	lead	lead	VERB
admet-3065	290	8	to	to	ADP
admet-3065	290	9	aggregation	aggregation	NOUN
admet-3065	290	10	in	in	ADP
admet-3065	290	11	the	the	DET
admet-3065	290	12	bloodstream	bloodstream	NOUN
admet-3065	290	13	[	[	X
admet-3065	290	14	152	152	NUM
admet-3065	290	15	]	]	PUNCT
admet-3065	290	16	.	.	PUNCT
admet-3065	291	1	liposome	liposome	VERB
admet-3065	291	2	fluidity	fluidity	NOUN
admet-3065	291	3	and	and	CCONJ
admet-3065	291	4	rigidity	rigidity	NOUN
admet-3065	291	5	the	the	DET
admet-3065	291	6	structure	structure	NOUN
admet-3065	291	7	of	of	ADP
admet-3065	291	8	the	the	DET
admet-3065	291	9	lipid	lipid	NOUN
admet-3065	291	10	tail	tail	NOUN
admet-3065	291	11	exerts	exert	VERB
admet-3065	291	12	a	a	DET
admet-3065	291	13	strong	strong	ADJ
admet-3065	291	14	influence	influence	NOUN
admet-3065	291	15	on	on	ADP
admet-3065	291	16	the	the	DET
admet-3065	291	17	phase	phase	NOUN
admet-3065	291	18	transition	transition	NOUN
admet-3065	291	19	temperature	temperature	NOUN
admet-3065	291	20	(	(	PUNCT
admet-3065	291	21	tc	tc	NOUN
admet-3065	291	22	)	)	PUNCT
admet-3065	291	23	of	of	ADP
admet-3065	291	24	lipids	lipid	NOUN
admet-3065	291	25	,	,	PUNCT
admet-3065	291	26	which	which	PRON
admet-3065	291	27	governs	govern	VERB
admet-3065	291	28	their	their	PRON
admet-3065	291	29	mechanical	mechanical	ADJ
admet-3065	291	30	stability	stability	NOUN
admet-3065	291	31	,	,	PUNCT
admet-3065	291	32	lateral	lateral	ADJ
admet-3065	291	33	diffusion	diffusion	NOUN
admet-3065	291	34	,	,	PUNCT
admet-3065	291	35	and	and	CCONJ
admet-3065	291	36	membrane	membrane	NOUN
admet-3065	291	37	permeability	permeability	NOUN
admet-3065	291	38	.	.	PUNCT
admet-3065	292	1	the	the	DET
admet-3065	292	2	membrane	membrane	NOUN
admet-3065	292	3	's	's	PART
admet-3065	292	4	permeability	permeability	NOUN
admet-3065	292	5	is	be	AUX
admet-3065	292	6	greatest	great	ADJ
admet-3065	292	7	near	near	ADP
admet-3065	292	8	tc	tc	NUM
admet-3065	292	9	due	due	ADP
admet-3065	292	10	to	to	ADP
admet-3065	292	11	the	the	DET
admet-3065	292	12	coexistence	coexistence	NOUN
admet-3065	292	13	and	and	CCONJ
admet-3065	292	14	dynamic	dynamic	ADJ
admet-3065	292	15	interconversion	interconversion	NOUN
admet-3065	292	16	of	of	ADP
admet-3065	292	17	the	the	DET
admet-3065	292	18	fluid	fluid	NOUN
admet-3065	292	19	and	and	CCONJ
admet-3065	292	20	gel	gel	NOUN
admet-3065	292	21	phases	phase	NOUN
admet-3065	292	22	[	[	X
admet-3065	292	23	153	153	NUM
admet-3065	292	24	]	]	PUNCT
admet-3065	292	25	.	.	PUNCT
admet-3065	293	1	this	this	DET
admet-3065	293	2	concept	concept	NOUN
admet-3065	293	3	has	have	AUX
admet-3065	293	4	been	be	AUX
admet-3065	293	5	widely	widely	ADV
admet-3065	293	6	exploited	exploit	VERB
admet-3065	293	7	in	in	ADP
admet-3065	293	8	the	the	DET
admet-3065	293	9	design	design	NOUN
admet-3065	293	10	of	of	ADP
admet-3065	293	11	thermally	thermally	ADV
admet-3065	293	12	responsive	responsive	ADJ
admet-3065	293	13	liposomal	liposomal	ADJ
admet-3065	293	14	drug	drug	NOUN
admet-3065	293	15	delivery	delivery	NOUN
admet-3065	293	16	vectors	vector	NOUN
admet-3065	293	17	[	[	X
admet-3065	293	18	154	154	NUM
admet-3065	293	19	]	]	PUNCT
admet-3065	293	20	.	.	PUNCT
admet-3065	294	1	lipids	lipid	NOUN
admet-3065	294	2	with	with	ADP
admet-3065	294	3	higher	high	ADJ
admet-3065	294	4	tc	tc	NOUN
admet-3065	294	5	values	value	NOUN
admet-3065	294	6	create	create	VERB
admet-3065	294	7	more	more	ADV
admet-3065	294	8	rigid	rigid	ADJ
admet-3065	294	9	membranes	membrane	NOUN
admet-3065	294	10	,	,	PUNCT
admet-3065	294	11	whereas	whereas	SCONJ
admet-3065	294	12	lower	low	ADJ
admet-3065	294	13	tc	tc	NOUN
admet-3065	294	14	lipids	lipid	NOUN
admet-3065	294	15	are	be	AUX
admet-3065	294	16	more	more	ADV
admet-3065	294	17	fluid	fluid	ADJ
admet-3065	294	18	.	.	PUNCT
admet-3065	295	1	this	this	DET
admet-3065	295	2	mechanical	mechanical	ADJ
admet-3065	295	3	property	property	NOUN
admet-3065	295	4	influences	influence	NOUN
admet-3065	295	5	both	both	CCONJ
admet-3065	295	6	cellular	cellular	ADJ
admet-3065	295	7	uptake	uptake	NOUN
admet-3065	295	8	as	as	ADV
admet-3065	295	9	well	well	ADV
admet-3065	295	10	as	as	ADP
admet-3065	295	11	ecm	ecm	NOUN
admet-3065	295	12	penetration	penetration	NOUN
admet-3065	295	13	by	by	ADP
admet-3065	295	14	liposomes	liposome	NOUN
admet-3065	295	15	[	[	X
admet-3065	295	16	155	155	NUM
admet-3065	295	17	]	]	PUNCT
admet-3065	295	18	.	.	PUNCT
admet-3065	296	1	schroeder	schroeder	PROPN
admet-3065	296	2	et	et	PROPN
admet-3065	296	3	al	al	PROPN
admet-3065	296	4	.	.	PUNCT
admet-3065	297	1	[	[	X
admet-3065	297	2	156	156	NUM
admet-3065	297	3	]	]	PUNCT
admet-3065	297	4	demonstrated	demonstrate	VERB
admet-3065	297	5	that	that	SCONJ
admet-3065	297	6	the	the	DET
admet-3065	297	7	internalization	internalization	NOUN
admet-3065	297	8	of	of	ADP
admet-3065	297	9	ph	ph	ADJ
admet-3065	297	10	-	-	ADJ
admet-3065	297	11	sensitive	sensitive	ADJ
admet-3065	297	12	cationic	cationic	ADJ
admet-3065	297	13	liposomes	liposome	NOUN
admet-3065	297	14	in	in	ADP
admet-3065	297	15	4t1	4t1	NUM
admet-3065	297	16	breast	breast	NOUN
admet-3065	297	17	cancer	cancer	NOUN
admet-3065	297	18	cells	cell	NOUN
admet-3065	297	19	was	be	AUX
admet-3065	297	20	enhanced	enhance	VERB
admet-3065	297	21	with	with	ADP
admet-3065	297	22	tail	tail	NOUN
admet-3065	297	23	length	length	NOUN
admet-3065	297	24	:	:	PUNCT
admet-3065	297	25	dspc	dspc	NOUN
admet-3065	297	26	(	(	PUNCT
admet-3065	297	27	18:0	18:0	NUM
admet-3065	297	28	)	)	PUNCT
admet-3065	297	29	>	>	X
admet-3065	297	30	dppc	dppc	PROPN
admet-3065	297	31	(	(	PUNCT
admet-3065	297	32	16:0	16:0	NUM
admet-3065	297	33	)	)	PUNCT
admet-3065	297	34	>	>	X
admet-3065	297	35	dmpc	dmpc	PROPN
admet-3065	297	36	(	(	PUNCT
admet-3065	297	37	14:0	14:0	NUM
admet-3065	297	38	)	)	PUNCT
admet-3065	298	1	[	[	X
admet-3065	298	2	157	157	NUM
admet-3065	298	3	]	]	PUNCT
admet-3065	298	4	.	.	PUNCT
admet-3065	299	1	since	since	SCONJ
admet-3065	299	2	tumours	tumour	NOUN
admet-3065	299	3	are	be	AUX
admet-3065	299	4	encapsulated	encapsulate	VERB
admet-3065	299	5	by	by	ADP
admet-3065	299	6	a	a	DET
admet-3065	299	7	dense	dense	ADJ
admet-3065	299	8	ecm	ecm	NOUN
admet-3065	299	9	,	,	PUNCT
admet-3065	299	10	liposome	liposome	VERB
admet-3065	299	11	deformability	deformability	NOUN
admet-3065	299	12	also	also	ADV
admet-3065	299	13	influences	influence	VERB
admet-3065	299	14	their	their	PRON
admet-3065	299	15	diffusion	diffusion	NOUN
admet-3065	299	16	and	and	CCONJ
admet-3065	299	17	retention	retention	NOUN
admet-3065	299	18	.	.	PUNCT
admet-3065	300	1	moderately	moderately	ADV
admet-3065	300	2	rigid	rigid	ADJ
admet-3065	300	3	dppc	dppc	NOUN
admet-3065	300	4	-	-	PUNCT
admet-3065	300	5	based	base	VERB
admet-3065	300	6	liposomes	liposome	NOUN
admet-3065	300	7	exhibited	exhibit	VERB
admet-3065	300	8	improved	improved	ADJ
admet-3065	300	9	penetration	penetration	NOUN
admet-3065	300	10	and	and	CCONJ
admet-3065	300	11	retention	retention	NOUN
admet-3065	300	12	in	in	ADP
admet-3065	300	13	multicellular	multicellular	ADJ
admet-3065	300	14	spheroids	spheroid	NOUN
admet-3065	300	15	with	with	ADP
admet-3065	300	16	a	a	DET
admet-3065	300	17	rich	rich	ADJ
admet-3065	300	18	fibrous	fibrous	ADJ
admet-3065	300	19	ecm	ecm	NOUN
admet-3065	300	20	[	[	X
admet-3065	300	21	158	158	NUM
admet-3065	300	22	]	]	PUNCT
admet-3065	300	23	.	.	PUNCT
admet-3065	301	1	lipid	lipid	ADJ
admet-3065	301	2	membrane	membrane	NOUN
admet-3065	301	3	fusion	fusion	NOUN
admet-3065	301	4	lipid	lipid	NOUN
admet-3065	301	5	membrane	membrane	NOUN
admet-3065	301	6	fusion	fusion	NOUN
admet-3065	301	7	is	be	AUX
admet-3065	301	8	a	a	DET
admet-3065	301	9	critical	critical	ADJ
admet-3065	301	10	process	process	NOUN
admet-3065	301	11	in	in	ADP
admet-3065	301	12	numerous	numerous	ADJ
admet-3065	301	13	biological	biological	ADJ
admet-3065	301	14	processes	process	NOUN
admet-3065	301	15	,	,	PUNCT
admet-3065	301	16	but	but	CCONJ
admet-3065	301	17	will	will	AUX
admet-3065	301	18	not	not	PART
admet-3065	301	19	occur	occur	VERB
admet-3065	301	20	spontaneously	spontaneously	ADV
admet-3065	301	21	[	[	X
admet-3065	301	22	159	159	NUM
admet-3065	301	23	]	]	PUNCT
admet-3065	301	24	.	.	PUNCT
admet-3065	302	1	fusion	fusion	NOUN
admet-3065	302	2	only	only	ADV
admet-3065	302	3	occurs	occur	VERB
admet-3065	302	4	when	when	SCONJ
admet-3065	302	5	membranes	membrane	NOUN
admet-3065	302	6	are	be	AUX
admet-3065	302	7	closely	closely	ADV
admet-3065	302	8	apposed	appose	VERB
admet-3065	302	9	and	and	CCONJ
admet-3065	302	10	both	both	CCONJ
admet-3065	302	11	electrostatic	electrostatic	ADJ
admet-3065	302	12	and	and	CCONJ
admet-3065	302	13	hydration	hydration	NOUN
admet-3065	302	14	barriers	barrier	NOUN
admet-3065	302	15	are	be	AUX
admet-3065	302	16	overcome	overcome	VERB
admet-3065	302	17	.	.	PUNCT
admet-3065	303	1	the	the	DET
admet-3065	303	2	process	process	NOUN
admet-3065	303	3	may	may	AUX
admet-3065	303	4	be	be	AUX
admet-3065	303	5	facilitated	facilitate	VERB
admet-3065	303	6	by	by	ADP
admet-3065	303	7	metal	metal	NOUN
admet-3065	303	8	ions	ion	NOUN
admet-3065	303	9	,	,	PUNCT
admet-3065	303	10	fusogenic	fusogenic	ADJ
admet-3065	303	11	lipids	lipid	NOUN
admet-3065	303	12	such	such	ADJ
admet-3065	303	13	as	as	ADP
admet-3065	303	14	phosphatidylethanolamine	phosphatidylethanolamine	PROPN
admet-3065	303	15	(	(	PUNCT
admet-3065	303	16	pe	pe	NOUN
admet-3065	303	17	)	)	PUNCT
admet-3065	303	18	,	,	PUNCT
admet-3065	303	19	and	and	CCONJ
admet-3065	303	20	specific	specific	ADJ
admet-3065	303	21	ligand	ligand	ADJ
admet-3065	303	22	-	-	PUNCT
admet-3065	303	23	receptor	receptor	NOUN
admet-3065	303	24	interactions	interaction	NOUN
admet-3065	303	25	[	[	X
admet-3065	303	26	160	160	NUM
admet-3065	303	27	]	]	PUNCT
admet-3065	303	28	.	.	PUNCT
admet-3065	304	1	kros	kros	PROPN
admet-3065	304	2	et	et	PROPN
admet-3065	304	3	al	al	PROPN
admet-3065	304	4	.	.	PUNCT
admet-3065	305	1	[	[	X
admet-3065	305	2	161	161	NUM
admet-3065	305	3	]	]	PUNCT
admet-3065	305	4	,	,	PUNCT
admet-3065	305	5	for	for	ADP
admet-3065	305	6	example	example	NOUN
admet-3065	305	7	,	,	PUNCT
admet-3065	305	8	employed	employ	VERB
admet-3065	305	9	coiled	coil	VERB
admet-3065	305	10	-	-	PUNCT
admet-3065	305	11	coil	coil	NOUN
admet-3065	305	12	-	-	PUNCT
admet-3065	305	13	peptides	peptide	NOUN
admet-3065	305	14	for	for	ADP
admet-3065	305	15	selective	selective	ADJ
admet-3065	305	16	liposomal	liposomal	ADJ
admet-3065	305	17	drug	drug	NOUN
admet-3065	305	18	delivery	delivery	NOUN
admet-3065	305	19	,	,	PUNCT
admet-3065	305	20	revealing	reveal	VERB
admet-3065	305	21	enhanced	enhance	VERB
admet-3065	305	22	cellular	cellular	ADJ
admet-3065	305	23	uptake	uptake	NOUN
admet-3065	305	24	via	via	ADP
admet-3065	305	25	predominantly	predominantly	ADV
admet-3065	305	26	membrane	membrane	ADJ
admet-3065	305	27	fusion	fusion	NOUN
admet-3065	305	28	rather	rather	ADV
admet-3065	305	29	than	than	ADP
admet-3065	305	30	endocytosis	endocytosis	NOUN
admet-3065	305	31	[	[	X
admet-3065	305	32	162	162	NUM
admet-3065	305	33	]	]	PUNCT
admet-3065	305	34	.	.	PUNCT
admet-3065	306	1	membrane	membrane	NOUN
admet-3065	306	2	-	-	PUNCT
admet-3065	306	3	fusogenic	fusogenic	ADJ
admet-3065	306	4	liposomes	liposome	NOUN
admet-3065	306	5	(	(	PUNCT
admet-3065	306	6	mflp	mflp	PROPN
admet-3065	306	7	)	)	PUNCT
admet-3065	306	8	that	that	PRON
admet-3065	306	9	were	be	AUX
admet-3065	306	10	functionalized	functionalize	VERB
admet-3065	306	11	with	with	ADP
admet-3065	306	12	a	a	DET
admet-3065	306	13	cell	cell	NOUN
admet-3065	306	14	-	-	PUNCT
admet-3065	306	15	penetrating	penetrate	VERB
admet-3065	306	16	arginine	arginine	NOUN
admet-3065	306	17	peptide	peptide	NOUN
admet-3065	306	18	and	and	CCONJ
admet-3065	306	19	a	a	DET
admet-3065	306	20	ph	ph	ADJ
admet-3065	306	21	-	-	ADJ
admet-3065	306	22	sensitive	sensitive	ADJ
admet-3065	306	23	peg	peg	NOUN
admet-3065	306	24	coating	coating	NOUN
admet-3065	306	25	.	.	PUNCT
admet-3065	307	1	after	after	ADP
admet-3065	307	2	the	the	DET
admet-3065	307	3	shedding	shedding	NOUN
admet-3065	307	4	of	of	ADP
admet-3065	307	5	the	the	DET
admet-3065	307	6	peg	peg	NOUN
admet-3065	307	7	chains	chain	NOUN
admet-3065	307	8	in	in	ADP
admet-3065	307	9	the	the	DET
admet-3065	307	10	acidic	acidic	ADJ
admet-3065	307	11	tumour	tumour	NOUN
admet-3065	307	12	environment	environment	NOUN
admet-3065	307	13	,	,	PUNCT
admet-3065	307	14	fusogenic	fusogenic	ADJ
admet-3065	307	15	peptides	peptide	NOUN
admet-3065	307	16	were	be	AUX
admet-3065	307	17	revealed	reveal	VERB
admet-3065	307	18	,	,	PUNCT
admet-3065	307	19	and	and	CCONJ
admet-3065	307	20	rapid	rapid	ADJ
admet-3065	307	21	membrane	membrane	NOUN
admet-3065	307	22	fusion	fusion	NOUN
admet-3065	307	23	and	and	CCONJ
admet-3065	307	24	cytoplasmic	cytoplasmic	ADJ
admet-3065	307	25	delivery	delivery	NOUN
admet-3065	307	26	of	of	ADP
admet-3065	307	27	drug	drug	NOUN
admet-3065	307	28	cargoes	cargo	NOUN
admet-3065	307	29	were	be	AUX
admet-3065	307	30	enabled	enable	VERB
admet-3065	307	31	within	within	ADP
admet-3065	307	32	30	30	NUM
admet-3065	307	33	seconds	second	NOUN
admet-3065	307	34	,	,	PUNCT
admet-3065	307	35	avoiding	avoid	VERB
admet-3065	307	36	endocytosis	endocytosis	NOUN
admet-3065	307	37	effect	effect	NOUN
admet-3065	307	38	of	of	ADP
admet-3065	307	39	lipid	lipid	ADJ
admet-3065	307	40	phase	phase	NOUN
admet-3065	307	41	in	in	ADP
admet-3065	307	42	the	the	DET
admet-3065	307	43	presence	presence	NOUN
admet-3065	307	44	of	of	ADP
admet-3065	307	45	cholesterol	cholesterol	NOUN
admet-3065	307	46	,	,	PUNCT
admet-3065	307	47	phospholipids	phospholipid	NOUN
admet-3065	307	48	can	can	AUX
admet-3065	307	49	exist	exist	VERB
admet-3065	307	50	in	in	ADP
admet-3065	307	51	a	a	DET
admet-3065	307	52	liquid	liquid	NOUN
admet-3065	307	53	-	-	PUNCT
admet-3065	307	54	ordered	order	VERB
admet-3065	307	55	(	(	PUNCT
admet-3065	307	56	lo	lo	NOUN
admet-3065	307	57	)	)	PUNCT
admet-3065	307	58	phase	phase	NOUN
admet-3065	307	59	,	,	PUNCT
admet-3065	307	60	as	as	ADV
admet-3065	307	61	well	well	ADV
admet-3065	307	62	as	as	ADP
admet-3065	307	63	the	the	DET
admet-3065	307	64	more	more	ADV
admet-3065	307	65	fluid	fluid	ADJ
admet-3065	307	66	liquid	liquid	NOUN
admet-3065	307	67	-	-	PUNCT
admet-3065	307	68	disordered	disorder	VERB
admet-3065	307	69	(	(	PUNCT
admet-3065	307	70	ld	ld	NOUN
admet-3065	307	71	)	)	PUNCT
admet-3065	307	72	phase	phase	NOUN
admet-3065	307	73	,	,	PUNCT
admet-3065	307	74	which	which	PRON
admet-3065	307	75	is	be	AUX
admet-3065	307	76	enriched	enrich	VERB
admet-3065	307	77	in	in	ADP
admet-3065	307	78	unsaturated	unsaturated	ADJ
admet-3065	307	79	lipid	lipid	NOUN
admet-3065	307	80	species	specie	NOUN
admet-3065	307	81	.	.	PUNCT
admet-3065	308	1	certain	certain	ADJ
admet-3065	308	2	ternary	ternary	ADJ
admet-3065	308	3	and	and	CCONJ
admet-3065	308	4	quaternary	quaternary	ADJ
admet-3065	308	5	lipid	lipid	NOUN
admet-3065	308	6	mixtures	mixture	NOUN
admet-3065	308	7	phase	phase	NOUN
admet-3065	308	8	separate	separate	ADJ
admet-3065	308	9	into	into	ADP
admet-3065	308	10	lo	lo	PROPN
admet-3065	308	11	and	and	CCONJ
admet-3065	308	12	ld	ld	PROPN
admet-3065	308	13	domains	domain	NOUN
admet-3065	308	14	[	[	X
admet-3065	308	15	150	150	NUM
admet-3065	308	16	]	]	PUNCT
admet-3065	308	17	.	.	PUNCT
admet-3065	309	1	stachowiak	stachowiak	PROPN
admet-3065	309	2	et	et	PROPN
admet-3065	309	3	al	al	PROPN
admet-3065	310	1	[	[	X
admet-3065	310	2	163	163	NUM
admet-3065	310	3	]	]	PUNCT
admet-3065	310	4	investigated	investigate	VERB
admet-3065	310	5	the	the	DET
admet-3065	310	6	use	use	NOUN
admet-3065	310	7	of	of	ADP
admet-3065	310	8	phase	phase	NOUN
admet-3065	310	9	-	-	PUNCT
admet-3065	310	10	separated	separate	VERB
admet-3065	310	11	liposomes	liposome	NOUN
admet-3065	310	12	for	for	ADP
admet-3065	310	13	enhanced	enhanced	ADJ
admet-3065	310	14	cytoplasmic	cytoplasmic	ADJ
admet-3065	310	15	delivery	delivery	NOUN
admet-3065	310	16	.	.	PUNCT
admet-3065	311	1	they	they	PRON
admet-3065	311	2	prepared	prepare	VERB
admet-3065	311	3	phase	phase	NOUN
admet-3065	311	4	-	-	PUNCT
admet-3065	311	5	separated	separate	VERB
admet-3065	311	6	liposomes	liposome	NOUN
admet-3065	311	7	composed	compose	VERB
admet-3065	311	8	of	of	ADP
admet-3065	311	9	dotap	dotap	NOUN
admet-3065	311	10	/	/	SYM
admet-3065	311	11	dppc	dppc	NOUN
admet-3065	311	12	/	/	SYM
admet-3065	311	13	cholesterol	cholesterol	NOUN
admet-3065	311	14	and	and	CCONJ
admet-3065	311	15	found	find	VERB
admet-3065	311	16	they	they	PRON
admet-3065	311	17	demonstrated	demonstrate	VERB
admet-3065	311	18	lipid	lipid	NOUN
admet-3065	311	19	transfer	transfer	NOUN
admet-3065	311	20	rates	rate	NOUN
admet-3065	311	21	8	8	NUM
admet-3065	311	22	to	to	PART
admet-3065	311	23	10	10	NUM
admet-3065	311	24	times	time	NOUN
admet-3065	311	25	higher	high	ADJ
admet-3065	311	26	to	to	ADP
admet-3065	311	27	giant	giant	ADJ
admet-3065	311	28	unilamellar	unilamellar	ADJ
admet-3065	311	29	vesicles	vesicle	NOUN
admet-3065	311	30	(	(	PUNCT
admet-3065	311	31	guvs	guvs	X
admet-3065	311	32	)	)	PUNCT
admet-3065	311	33	than	than	ADP
admet-3065	311	34	their	their	PRON
admet-3065	311	35	non	non	ADJ
admet-3065	311	36	-	-	ADJ
admet-3065	311	37	phase	phase	NOUN
admet-3065	311	38	-	-	PUNCT
admet-3065	311	39	separated	separate	VERB
admet-3065	311	40	counterparts	counterpart	NOUN
admet-3065	311	41	.	.	PUNCT
admet-3065	312	1	in	in	ADP
admet-3065	312	2	cellular	cellular	ADJ
admet-3065	312	3	uptake	uptake	ADJ
admet-3065	312	4	experiments	experiment	NOUN
admet-3065	312	5	,	,	PUNCT
admet-3065	312	6	phase	phase	NOUN
admet-3065	312	7	-	-	PUNCT
admet-3065	312	8	separated	separate	VERB
admet-3065	312	9	liposomes	liposome	NOUN
admet-3065	312	10	containing	contain	VERB
admet-3065	312	11	5	5	NUM
admet-3065	312	12	mol.%	mol.%	NOUN
admet-3065	312	13	dotap	dotap	NOUN
admet-3065	312	14	achieved	achieve	VERB
admet-3065	312	15	4	4	NUM
admet-3065	312	16	-	-	SYM
admet-3065	312	17	5	5	NUM
admet-3065	312	18	-	-	ADJ
admet-3065	312	19	fold	fold	ADJ
admet-3065	312	20	greater	great	ADJ
admet-3065	312	21	fusion	fusion	NOUN
admet-3065	312	22	efficiency	efficiency	NOUN
admet-3065	312	23	with	with	ADP
admet-3065	312	24	cells	cell	NOUN
admet-3065	312	25	compared	compare	VERB
admet-3065	312	26	to	to	ADP
admet-3065	312	27	homogenous	homogenous	ADJ
admet-3065	312	28	liposomes	liposome	NOUN
admet-3065	312	29	,	,	PUNCT
admet-3065	312	30	likely	likely	ADJ
admet-3065	312	31	due	due	ADP
admet-3065	312	32	to	to	ADP
admet-3065	312	33	the	the	DET
admet-3065	312	34	concentration	concentration	NOUN
admet-3065	312	35	of	of	ADP
admet-3065	312	36	dotap	dotap	NOUN
admet-3065	312	37	in	in	ADP
admet-3065	312	38	distinct	distinct	ADJ
admet-3065	312	39	membrane	membrane	NOUN
admet-3065	312	40	domains	domain	NOUN
admet-3065	312	41	.	.	PUNCT
admet-3065	313	1	role	role	NOUN
admet-3065	313	2	of	of	ADP
admet-3065	313	3	pegylation	pegylation	NOUN
admet-3065	313	4	polyethylene	polyethylene	NOUN
admet-3065	313	5	glycol	glycol	NOUN
admet-3065	313	6	(	(	PUNCT
admet-3065	313	7	peg	peg	NOUN
admet-3065	313	8	)	)	PUNCT
admet-3065	313	9	modification	modification	NOUN
admet-3065	313	10	,	,	PUNCT
admet-3065	313	11	or	or	CCONJ
admet-3065	313	12	pegylation	pegylation	NOUN
admet-3065	313	13	,	,	PUNCT
admet-3065	313	14	is	be	AUX
admet-3065	313	15	a	a	DET
admet-3065	313	16	widely	widely	ADV
admet-3065	313	17	utilized	utilize	VERB
admet-3065	313	18	strategy	strategy	NOUN
admet-3065	313	19	to	to	PART
admet-3065	313	20	prolong	prolong	VERB
admet-3065	313	21	liposome	liposome	NOUN
admet-3065	313	22	circulation	circulation	NOUN
admet-3065	313	23	by	by	ADP
admet-3065	313	24	reducing	reduce	VERB
admet-3065	313	25	plasma	plasma	NOUN
admet-3065	313	26	protein	protein	NOUN
admet-3065	313	27	adsorption	adsorption	NOUN
admet-3065	313	28	and	and	CCONJ
admet-3065	313	29	thereby	thereby	ADV
admet-3065	313	30	minimizing	minimize	VERB
admet-3065	313	31	phagocytic	phagocytic	ADJ
admet-3065	313	32	clearance	clearance	NOUN
admet-3065	313	33	.	.	PUNCT
admet-3065	314	1	typically	typically	ADV
admet-3065	314	2	,	,	PUNCT
admet-3065	314	3	peg	peg	NOUN
admet-3065	314	4	chains	chain	NOUN
admet-3065	314	5	are	be	AUX
admet-3065	314	6	anchored	anchor	VERB
admet-3065	314	7	to	to	ADP
admet-3065	314	8	liposomes	liposome	NOUN
admet-3065	314	9	using	use	VERB
admet-3065	314	10	pegylated	pegylate	VERB
admet-3065	314	11	lipids	lipid	NOUN
admet-3065	314	12	such	such	ADJ
admet-3065	314	13	as	as	ADP
admet-3065	314	14	peg	peg	NOUN
admet-3065	314	15	-	-	PUNCT
admet-3065	314	16	dspe	dspe	PROPN
admet-3065	314	17	.	.	PUNCT
admet-3065	315	1	huang	huang	PROPN
admet-3065	315	2	and	and	CCONJ
admet-3065	315	3	colleagues	colleague	NOUN
admet-3065	315	4	demonstrated	demonstrate	VERB
admet-3065	315	5	that	that	SCONJ
admet-3065	315	6	pegylated	pegylate	VERB
admet-3065	315	7	large	large	ADJ
admet-3065	315	8	unilamellar	unilamellar	ADJ
admet-3065	315	9	liposomes	liposome	NOUN
admet-3065	315	10	(	(	PUNCT
admet-3065	315	11	200	200	X
admet-3065	315	12	nm	nm	NOUN
admet-3065	315	13	)	)	PUNCT
admet-3065	315	14	exhibited	exhibit	VERB
admet-3065	315	15	a	a	DET
admet-3065	315	16	circulation	circulation	NOUN
admet-3065	315	17	half	half	ADJ
admet-3065	315	18	-	-	PUNCT
admet-3065	315	19	life	life	NOUN
admet-3065	315	20	of	of	ADP
admet-3065	315	21	approximately	approximately	ADV
admet-3065	315	22	5	5	NUM
admet-3065	315	23	hours	hour	NOUN
admet-3065	315	24	,	,	PUNCT
admet-3065	315	25	in	in	ADP
admet-3065	315	26	contrast	contrast	NOUN
admet-3065	315	27	to	to	ADP
admet-3065	315	28	less	less	ADJ
admet-3065	315	29	than	than	ADP
admet-3065	315	30	30	30	NUM
admet-3065	315	31	minutes	minute	NOUN
admet-3065	315	32	for	for	ADP
admet-3065	315	33	non	non	ADJ
admet-3065	315	34	-	-	ADJ
admet-3065	315	35	pegylated	pegylated	ADJ
admet-3065	315	36	counterparts	counterpart	NOUN
admet-3065	315	37	[	[	X
admet-3065	315	38	164	164	NUM
admet-3065	315	39	]	]	PUNCT
admet-3065	315	40	.	.	PUNCT
admet-3065	316	1	the	the	DET
admet-3065	316	2	impact	impact	NOUN
admet-3065	316	3	of	of	ADP
admet-3065	316	4	peg	peg	NOUN
admet-3065	316	5	on	on	ADP
admet-3065	316	6	liposome	liposome	NOUN
admet-3065	316	7	behaviour	behaviour	NOUN
admet-3065	316	8	depends	depend	VERB
admet-3065	316	9	on	on	ADP
admet-3065	316	10	both	both	CCONJ
admet-3065	316	11	its	its	PRON
admet-3065	316	12	molecular	molecular	ADJ
admet-3065	316	13	weight	weight	NOUN
admet-3065	316	14	and	and	CCONJ
admet-3065	316	15	surface	surface	NOUN
admet-3065	316	16	density	density	NOUN
admet-3065	316	17	[	[	X
admet-3065	316	18	165	165	NUM
admet-3065	316	19	]	]	PUNCT
admet-3065	316	20	.	.	PUNCT
admet-3065	317	1	while	while	SCONJ
admet-3065	317	2	pegylation	pegylation	NOUN
admet-3065	317	3	generally	generally	ADV
admet-3065	317	4	enhances	enhance	VERB
admet-3065	317	5	circulation	circulation	NOUN
admet-3065	317	6	time	time	NOUN
admet-3065	317	7	,	,	PUNCT
admet-3065	317	8	excessive	excessive	ADJ
admet-3065	317	9	peg	peg	NOUN
admet-3065	317	10	can	can	AUX
admet-3065	317	11	adversely	adversely	ADV
admet-3065	317	12	affect	affect	VERB
admet-3065	317	13	drug	drug	NOUN
admet-3065	317	14	delivery	delivery	NOUN
admet-3065	317	15	admet	admet	PROPN
admet-3065	317	16	&	&	CCONJ
admet-3065	317	17	dmpk	dmpk	PROPN
admet-3065	317	18	00(0	00(0	PROPN
admet-3065	317	19	)	)	PUNCT
admet-3065	317	20	(	(	PUNCT
admet-3065	317	21	2025	2025	NUM
admet-3065	317	22	)	)	PUNCT
admet-3065	317	23	3065	3065	NUM
admet-3065	317	24	liposome	liposome	NOUN
admet-3065	317	25	-	-	PUNCT
admet-3065	317	26	mediated	mediate	VERB
admet-3065	317	27	gene	gene	NOUN
admet-3065	317	28	delivery	delivery	NOUN
admet-3065	317	29	doi	doi	NOUN
admet-3065	317	30	:	:	PUNCT
admet-3065	317	31	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	317	32	15	15	NUM
admet-3065	317	33	performance	performance	NOUN
admet-3065	317	34	by	by	ADP
admet-3065	317	35	reducing	reduce	VERB
admet-3065	317	36	cellular	cellular	ADJ
admet-3065	317	37	uptake	uptake	NOUN
admet-3065	317	38	and	and	CCONJ
admet-3065	317	39	impairing	impair	VERB
admet-3065	317	40	endosomal	endosomal	ADJ
admet-3065	317	41	escape	escape	NOUN
admet-3065	317	42	[	[	NOUN
admet-3065	317	43	165	165	NUM
admet-3065	317	44	]	]	PUNCT
admet-3065	317	45	.	.	PUNCT
admet-3065	318	1	moreover	moreover	ADV
admet-3065	318	2	,	,	PUNCT
admet-3065	318	3	repeated	repeated	ADJ
admet-3065	318	4	administration	administration	NOUN
admet-3065	318	5	of	of	ADP
admet-3065	318	6	pegylated	pegylated	ADJ
admet-3065	318	7	liposomes	liposome	NOUN
admet-3065	318	8	may	may	AUX
admet-3065	318	9	trigger	trigger	VERB
admet-3065	318	10	the	the	DET
admet-3065	318	11	accelerated	accelerated	ADJ
admet-3065	318	12	blood	blood	NOUN
admet-3065	318	13	clearance	clearance	NOUN
admet-3065	318	14	(	(	PUNCT
admet-3065	318	15	abc	abc	PROPN
admet-3065	318	16	)	)	PUNCT
admet-3065	318	17	phenomenon	phenomenon	NOUN
admet-3065	319	1	[	[	X
admet-3065	319	2	166	166	NUM
admet-3065	319	3	]	]	PUNCT
admet-3065	319	4	.	.	PUNCT
admet-3065	320	1	strategies	strategy	NOUN
admet-3065	320	2	for	for	ADP
admet-3065	320	3	targeted	target	VERB
admet-3065	320	4	gene	gene	NOUN
admet-3065	320	5	delivery	delivery	NOUN
admet-3065	320	6	the	the	DET
admet-3065	320	7	success	success	NOUN
admet-3065	320	8	of	of	ADP
admet-3065	320	9	gene	gene	NOUN
admet-3065	320	10	therapy	therapy	NOUN
admet-3065	320	11	relies	rely	VERB
admet-3065	320	12	on	on	ADP
admet-3065	320	13	the	the	DET
admet-3065	320	14	ability	ability	NOUN
admet-3065	320	15	to	to	PART
admet-3065	320	16	selectively	selectively	ADV
admet-3065	320	17	deliver	deliver	VERB
admet-3065	320	18	therapeutic	therapeutic	ADJ
admet-3065	320	19	genes	gene	NOUN
admet-3065	320	20	to	to	ADP
admet-3065	320	21	a	a	DET
admet-3065	320	22	sufficient	sufficient	ADJ
admet-3065	320	23	number	number	NOUN
admet-3065	320	24	of	of	ADP
admet-3065	320	25	target	target	NOUN
admet-3065	320	26	cells	cell	NOUN
admet-3065	320	27	[	[	X
admet-3065	320	28	167,168	167,168	NUM
admet-3065	320	29	]	]	PUNCT
admet-3065	320	30	.	.	PUNCT
admet-3065	321	1	this	this	PRON
admet-3065	321	2	can	can	AUX
admet-3065	321	3	be	be	AUX
admet-3065	321	4	achieved	achieve	VERB
admet-3065	321	5	through	through	ADP
admet-3065	321	6	physical	physical	ADJ
admet-3065	321	7	targeting	targeting	NOUN
admet-3065	321	8	and	and	CCONJ
admet-3065	321	9	molecular	molecular	ADJ
admet-3065	321	10	biological	biological	ADJ
admet-3065	321	11	targeting	target	VERB
admet-3065	321	12	[	[	X
admet-3065	321	13	169,170	169,170	NUM
admet-3065	321	14	]	]	PUNCT
admet-3065	321	15	.	.	PUNCT
admet-3065	322	1	physical	physical	ADJ
admet-3065	322	2	targeting	targeting	NOUN
admet-3065	322	3	relies	rely	VERB
admet-3065	322	4	on	on	ADP
admet-3065	322	5	the	the	DET
admet-3065	322	6	attachment	attachment	NOUN
admet-3065	322	7	of	of	ADP
admet-3065	322	8	ligands	ligand	NOUN
admet-3065	322	9	to	to	ADP
admet-3065	322	10	the	the	DET
admet-3065	322	11	delivery	delivery	NOUN
admet-3065	322	12	vehicle	vehicle	NOUN
admet-3065	322	13	that	that	PRON
admet-3065	322	14	bind	bind	VERB
admet-3065	322	15	to	to	ADP
admet-3065	322	16	cell	cell	NOUN
admet-3065	322	17	-	-	PUNCT
admet-3065	322	18	surface	surface	NOUN
admet-3065	322	19	receptors	receptor	NOUN
admet-3065	322	20	unique	unique	ADJ
admet-3065	322	21	to	to	ADP
admet-3065	322	22	the	the	DET
admet-3065	322	23	target	target	NOUN
admet-3065	322	24	cells	cell	NOUN
admet-3065	322	25	[	[	X
admet-3065	322	26	171,172	171,172	NUM
admet-3065	322	27	]	]	PUNCT
admet-3065	322	28	.	.	PUNCT
admet-3065	323	1	molecular	molecular	ADJ
admet-3065	323	2	biological	biological	ADJ
admet-3065	323	3	targeting	targeting	NOUN
admet-3065	323	4	refers	refer	VERB
admet-3065	323	5	to	to	ADP
admet-3065	323	6	the	the	DET
admet-3065	323	7	selective	selective	ADJ
admet-3065	323	8	expression	expression	NOUN
admet-3065	323	9	of	of	ADP
admet-3065	323	10	a	a	DET
admet-3065	323	11	therapeutic	therapeutic	ADJ
admet-3065	323	12	gene	gene	NOUN
admet-3065	323	13	in	in	ADP
admet-3065	323	14	the	the	DET
admet-3065	323	15	target	target	NOUN
admet-3065	323	16	cell	cell	NOUN
admet-3065	323	17	using	use	VERB
admet-3065	323	18	a	a	DET
admet-3065	323	19	specific	specific	ADJ
admet-3065	323	20	promoter	promoter	NOUN
admet-3065	323	21	[	[	X
admet-3065	323	22	173,174	173,174	NUM
admet-3065	323	23	]	]	PUNCT
admet-3065	323	24	.	.	PUNCT
admet-3065	324	1	active	active	ADJ
admet-3065	324	2	targeting	target	VERB
admet-3065	324	3	actively	actively	ADV
admet-3065	324	4	targeted	target	VERB
admet-3065	324	5	liposomes	liposome	NOUN
admet-3065	324	6	represent	represent	VERB
admet-3065	324	7	a	a	DET
admet-3065	324	8	third	third	ADJ
admet-3065	324	9	-	-	PUNCT
admet-3065	324	10	generation	generation	NOUN
admet-3065	324	11	advancement	advancement	NOUN
admet-3065	324	12	designed	design	VERB
admet-3065	324	13	to	to	PART
admet-3065	324	14	enhance	enhance	VERB
admet-3065	324	15	therapeutic	therapeutic	ADJ
admet-3065	324	16	selectivity	selectivity	NOUN
admet-3065	324	17	and	and	CCONJ
admet-3065	324	18	cellular	cellular	ADJ
admet-3065	324	19	uptake	uptake	NOUN
admet-3065	324	20	[	[	X
admet-3065	324	21	175,176	175,176	NUM
admet-3065	324	22	]	]	PUNCT
admet-3065	324	23	.	.	PUNCT
admet-3065	325	1	unlike	unlike	ADP
admet-3065	325	2	passive	passive	ADJ
admet-3065	325	3	targeting	targeting	NOUN
admet-3065	325	4	,	,	PUNCT
admet-3065	325	5	which	which	PRON
admet-3065	325	6	relies	rely	VERB
admet-3065	325	7	on	on	ADP
admet-3065	325	8	the	the	DET
admet-3065	325	9	enhanced	enhanced	ADJ
admet-3065	325	10	permeability	permeability	NOUN
admet-3065	325	11	and	and	CCONJ
admet-3065	325	12	retention	retention	NOUN
admet-3065	325	13	(	(	PUNCT
admet-3065	325	14	epr	epr	ADJ
admet-3065	325	15	)	)	PUNCT
admet-3065	325	16	effect	effect	NOUN
admet-3065	325	17	in	in	ADP
admet-3065	325	18	tumour	tumour	ADJ
admet-3065	325	19	tissues	tissue	NOUN
admet-3065	325	20	,	,	PUNCT
admet-3065	325	21	active	active	ADJ
admet-3065	325	22	targeting	targeting	NOUN
admet-3065	325	23	employs	employ	VERB
admet-3065	325	24	molecular	molecular	ADJ
admet-3065	325	25	recognition	recognition	NOUN
admet-3065	325	26	elements	element	NOUN
admet-3065	325	27	to	to	PART
admet-3065	325	28	facilitate	facilitate	VERB
admet-3065	325	29	selective	selective	ADJ
admet-3065	325	30	binding	bind	VERB
admet-3065	325	31	to	to	ADP
admet-3065	325	32	diseased	diseased	ADJ
admet-3065	325	33	cells	cell	NOUN
admet-3065	325	34	,	,	PUNCT
admet-3065	325	35	thereby	thereby	ADV
admet-3065	325	36	promoting	promote	VERB
admet-3065	325	37	receptor	receptor	NOUN
admet-3065	325	38	-	-	PUNCT
admet-3065	325	39	mediated	mediate	VERB
admet-3065	325	40	endocytosis	endocytosis	NOUN
admet-3065	325	41	[	[	X
admet-3065	325	42	177	177	NUM
admet-3065	325	43	]	]	PUNCT
admet-3065	325	44	.	.	PUNCT
admet-3065	326	1	actively	actively	ADV
admet-3065	326	2	targeted	target	VERB
admet-3065	326	3	liposomes	liposome	NOUN
admet-3065	326	4	have	have	AUX
admet-3065	326	5	been	be	AUX
admet-3065	326	6	developed	develop	VERB
admet-3065	326	7	by	by	ADP
admet-3065	326	8	incorporating	incorporate	VERB
admet-3065	326	9	ligands	ligand	NOUN
admet-3065	326	10	such	such	ADJ
admet-3065	326	11	as	as	ADP
admet-3065	326	12	simple	simple	ADJ
admet-3065	326	13	peptides	peptide	NOUN
admet-3065	326	14	,	,	PUNCT
admet-3065	326	15	antibodies	antibodie	VERB
admet-3065	326	16	and	and	CCONJ
admet-3065	326	17	their	their	PRON
admet-3065	326	18	fragments	fragment	NOUN
admet-3065	326	19	,	,	PUNCT
admet-3065	326	20	carbohydrates	carbohydrate	NOUN
admet-3065	326	21	,	,	PUNCT
admet-3065	326	22	nucleic	nucleic	ADJ
admet-3065	326	23	acids	acid	NOUN
admet-3065	326	24	,	,	PUNCT
admet-3065	326	25	and	and	CCONJ
admet-3065	326	26	vitamins	vitamin	NOUN
admet-3065	326	27	,	,	PUNCT
admet-3065	326	28	which	which	PRON
admet-3065	326	29	recognize	recognize	VERB
admet-3065	326	30	and	and	CCONJ
admet-3065	326	31	bind	bind	VERB
admet-3065	326	32	to	to	ADP
admet-3065	326	33	overexpressed	overexpresse	VERB
admet-3065	326	34	receptors	receptor	NOUN
admet-3065	326	35	on	on	ADP
admet-3065	326	36	tumour	tumour	ADJ
admet-3065	326	37	cells	cell	NOUN
admet-3065	326	38	[	[	X
admet-3065	326	39	178	178	NUM
admet-3065	326	40	-	-	SYM
admet-3065	326	41	180	180	NUM
admet-3065	326	42	]	]	PUNCT
admet-3065	326	43	.	.	PUNCT
admet-3065	327	1	overall	overall	ADJ
admet-3065	327	2	,	,	PUNCT
admet-3065	327	3	active	active	ADJ
admet-3065	327	4	targeting	targeting	NOUN
admet-3065	327	5	facilitates	facilitate	VERB
admet-3065	327	6	the	the	DET
admet-3065	327	7	precise	precise	ADJ
admet-3065	327	8	localization	localization	NOUN
admet-3065	327	9	of	of	ADP
admet-3065	327	10	therapeutics	therapeutic	NOUN
admet-3065	327	11	at	at	ADP
admet-3065	327	12	the	the	DET
admet-3065	327	13	site	site	NOUN
admet-3065	327	14	of	of	ADP
admet-3065	327	15	action	action	NOUN
admet-3065	327	16	,	,	PUNCT
admet-3065	327	17	enabling	enable	VERB
admet-3065	327	18	lower	low	ADJ
admet-3065	327	19	drug	drug	NOUN
admet-3065	327	20	doses	dose	NOUN
admet-3065	327	21	and	and	CCONJ
admet-3065	327	22	reduced	reduce	VERB
admet-3065	327	23	systemic	systemic	ADJ
admet-3065	327	24	toxicity	toxicity	NOUN
admet-3065	327	25	[	[	X
admet-3065	327	26	181	181	NUM
admet-3065	327	27	]	]	PUNCT
admet-3065	327	28	.	.	PUNCT
admet-3065	328	1	targeting	target	VERB
admet-3065	328	2	ligands	ligand	NOUN
admet-3065	328	3	antibodies	antibodie	VERB
admet-3065	328	4	(	(	PUNCT
admet-3065	328	5	immunoliposomes	immunoliposome	NOUN
admet-3065	328	6	)	)	PUNCT
admet-3065	328	7	antibodies	antibody	NOUN
admet-3065	328	8	are	be	AUX
admet-3065	328	9	glycoproteins	glycoprotein	NOUN
admet-3065	328	10	produced	produce	VERB
admet-3065	328	11	by	by	ADP
admet-3065	328	12	the	the	DET
admet-3065	328	13	immune	immune	ADJ
admet-3065	328	14	system	system	NOUN
admet-3065	328	15	that	that	PRON
admet-3065	328	16	selectively	selectively	ADV
admet-3065	328	17	recognize	recognize	VERB
admet-3065	328	18	and	and	CCONJ
admet-3065	328	19	bind	bind	VERB
admet-3065	328	20	to	to	ADP
admet-3065	328	21	antigens	antigen	NOUN
admet-3065	328	22	[	[	X
admet-3065	328	23	182,183	182,183	NUM
admet-3065	328	24	]	]	PUNCT
admet-3065	328	25	.	.	PUNCT
admet-3065	329	1	by	by	ADP
admet-3065	329	2	attaching	attach	VERB
admet-3065	329	3	antibodies	antibody	NOUN
admet-3065	329	4	to	to	PART
admet-3065	329	5	liposome	liposome	VERB
admet-3065	329	6	surfaces	surface	NOUN
admet-3065	329	7	,	,	PUNCT
admet-3065	329	8	it	it	PRON
admet-3065	329	9	is	be	AUX
admet-3065	329	10	possible	possible	ADJ
admet-3065	329	11	to	to	PART
admet-3065	329	12	create	create	VERB
admet-3065	329	13	highly	highly	ADV
admet-3065	329	14	specific	specific	ADJ
admet-3065	329	15	drugloaded	drugloade	VERB
admet-3065	329	16	nanoparticles	nanoparticle	NOUN
admet-3065	329	17	,	,	PUNCT
admet-3065	329	18	so	so	ADV
admet-3065	329	19	-	-	PUNCT
admet-3065	329	20	called	call	VERB
admet-3065	329	21	immunoliposomes	immunoliposome	NOUN
admet-3065	330	1	[	[	X
admet-3065	330	2	184	184	NUM
admet-3065	330	3	]	]	PUNCT
admet-3065	330	4	.	.	PUNCT
admet-3065	331	1	this	this	DET
admet-3065	331	2	approach	approach	NOUN
admet-3065	331	3	has	have	AUX
admet-3065	331	4	shown	show	VERB
admet-3065	331	5	promise	promise	NOUN
admet-3065	331	6	for	for	ADP
admet-3065	331	7	better	well	ADJ
admet-3065	331	8	targeted	target	VERB
admet-3065	331	9	delivery	delivery	NOUN
admet-3065	331	10	of	of	ADP
admet-3065	331	11	therapeutics	therapeutic	NOUN
admet-3065	331	12	;	;	PUNCT
admet-3065	331	13	however	however	ADV
admet-3065	331	14	,	,	PUNCT
admet-3065	331	15	the	the	DET
admet-3065	331	16	results	result	NOUN
admet-3065	331	17	have	have	AUX
admet-3065	331	18	been	be	AUX
admet-3065	331	19	inconsistent	inconsistent	ADJ
admet-3065	331	20	[	[	X
admet-3065	331	21	185,186	185,186	NUM
admet-3065	331	22	]	]	PUNCT
admet-3065	331	23	.	.	PUNCT
admet-3065	332	1	recently	recently	ADV
admet-3065	332	2	,	,	PUNCT
admet-3065	332	3	experiments	experiment	NOUN
admet-3065	332	4	have	have	AUX
admet-3065	332	5	shown	show	VERB
admet-3065	332	6	that	that	SCONJ
admet-3065	332	7	the	the	DET
admet-3065	332	8	utilization	utilization	NOUN
admet-3065	332	9	of	of	ADP
admet-3065	332	10	only	only	ADV
admet-3065	332	11	the	the	DET
admet-3065	332	12	fab	fab	ADJ
admet-3065	332	13	portion	portion	NOUN
admet-3065	332	14	of	of	ADP
admet-3065	332	15	the	the	DET
admet-3065	332	16	antibody	antibody	NOUN
admet-3065	332	17	can	can	AUX
admet-3065	332	18	be	be	AUX
admet-3065	332	19	more	more	ADV
admet-3065	332	20	effective	effective	ADJ
admet-3065	332	21	than	than	ADP
admet-3065	332	22	the	the	DET
admet-3065	332	23	whole	whole	ADJ
admet-3065	332	24	antibody	antibody	NOUN
admet-3065	332	25	[	[	X
admet-3065	332	26	187	187	NUM
admet-3065	332	27	-	-	SYM
admet-3065	332	28	189	189	NUM
admet-3065	332	29	]	]	PUNCT
admet-3065	332	30	.	.	PUNCT
admet-3065	333	1	whole	whole	ADJ
admet-3065	333	2	antibodies	antibody	NOUN
admet-3065	333	3	can	can	AUX
admet-3065	333	4	lead	lead	VERB
admet-3065	333	5	to	to	ADP
admet-3065	333	6	enhanced	enhanced	ADJ
admet-3065	333	7	immunogenicity	immunogenicity	NOUN
admet-3065	333	8	,	,	PUNCT
admet-3065	333	9	larger	large	ADJ
admet-3065	333	10	particle	particle	NOUN
admet-3065	333	11	sizes	size	NOUN
admet-3065	333	12	,	,	PUNCT
admet-3065	333	13	and	and	CCONJ
admet-3065	333	14	reduced	reduce	VERB
admet-3065	333	15	efficacy	efficacy	NOUN
admet-3065	333	16	compared	compare	VERB
admet-3065	333	17	to	to	ADP
admet-3065	333	18	liposomes	liposome	NOUN
admet-3065	333	19	coupled	couple	VERB
admet-3065	333	20	with	with	ADP
admet-3065	333	21	fab	fab	NOUN
admet-3065	333	22	fragments	fragment	NOUN
admet-3065	333	23	[	[	X
admet-3065	333	24	188,190	188,190	NUM
admet-3065	333	25	]	]	PUNCT
admet-3065	333	26	.	.	PUNCT
admet-3065	334	1	peptides	peptide	NOUN
admet-3065	334	2	peptides	peptide	NOUN
admet-3065	334	3	,	,	PUNCT
admet-3065	334	4	being	be	AUX
admet-3065	334	5	short	short	ADJ
admet-3065	334	6	chains	chain	NOUN
admet-3065	334	7	of	of	ADP
admet-3065	334	8	amino	amino	ADJ
admet-3065	334	9	acids	acid	NOUN
admet-3065	334	10	,	,	PUNCT
admet-3065	334	11	have	have	AUX
admet-3065	334	12	long	long	ADV
admet-3065	334	13	been	be	AUX
admet-3065	334	14	known	know	VERB
admet-3065	334	15	for	for	ADP
admet-3065	334	16	their	their	PRON
admet-3065	334	17	therapeutic	therapeutic	ADJ
admet-3065	334	18	potential	potential	NOUN
admet-3065	334	19	[	[	X
admet-3065	334	20	191	191	NUM
admet-3065	334	21	]	]	PUNCT
admet-3065	334	22	.	.	PUNCT
admet-3065	335	1	their	their	PRON
admet-3065	335	2	unique	unique	ADJ
admet-3065	335	3	structure	structure	NOUN
admet-3065	335	4	enables	enable	VERB
admet-3065	335	5	them	they	PRON
admet-3065	335	6	to	to	PART
admet-3065	335	7	modulate	modulate	VERB
admet-3065	335	8	protein	protein	NOUN
admet-3065	335	9	-	-	PUNCT
admet-3065	335	10	protein	protein	NOUN
admet-3065	335	11	interactions	interaction	NOUN
admet-3065	335	12	[	[	X
admet-3065	335	13	192	192	NUM
admet-3065	335	14	]	]	PUNCT
admet-3065	335	15	.	.	PUNCT
admet-3065	336	1	due	due	ADP
admet-3065	336	2	to	to	ADP
admet-3065	336	3	their	their	PRON
admet-3065	336	4	specificity	specificity	NOUN
admet-3065	336	5	and	and	CCONJ
admet-3065	336	6	therapeutic	therapeutic	ADJ
admet-3065	336	7	activity	activity	NOUN
admet-3065	336	8	,	,	PUNCT
admet-3065	336	9	peptides	peptide	NOUN
admet-3065	336	10	have	have	AUX
admet-3065	336	11	also	also	ADV
admet-3065	336	12	been	be	AUX
admet-3065	336	13	conjugated	conjugate	VERB
admet-3065	336	14	to	to	ADP
admet-3065	336	15	liposomes	liposome	NOUN
admet-3065	336	16	for	for	ADP
admet-3065	336	17	targeted	target	VERB
admet-3065	336	18	drug	drug	NOUN
admet-3065	336	19	delivery	delivery	NOUN
admet-3065	336	20	[	[	X
admet-3065	336	21	193	193	NUM
admet-3065	336	22	]	]	PUNCT
admet-3065	336	23	.	.	PUNCT
admet-3065	337	1	diseased	diseased	ADJ
admet-3065	337	2	tissues	tissue	NOUN
admet-3065	337	3	often	often	ADV
admet-3065	337	4	overexpress	overexpress	VERB
admet-3065	337	5	certain	certain	ADJ
admet-3065	337	6	receptors	receptor	NOUN
admet-3065	337	7	(	(	PUNCT
admet-3065	337	8	e.g.	e.g.	ADV
admet-3065	337	9	her2	her2	VERB
admet-3065	337	10	in	in	ADP
admet-3065	337	11	breast	breast	NOUN
admet-3065	337	12	cancer	cancer	NOUN
admet-3065	337	13	)	)	PUNCT
admet-3065	337	14	,	,	PUNCT
admet-3065	337	15	and	and	CCONJ
admet-3065	337	16	peptides	peptide	NOUN
admet-3065	337	17	can	can	AUX
admet-3065	337	18	be	be	AUX
admet-3065	337	19	designed	design	VERB
admet-3065	337	20	to	to	PART
admet-3065	337	21	bind	bind	VERB
admet-3065	337	22	selectively	selectively	ADV
admet-3065	337	23	to	to	ADP
admet-3065	337	24	these	these	DET
admet-3065	337	25	receptors	receptor	NOUN
admet-3065	337	26	,	,	PUNCT
admet-3065	337	27	enabling	enable	VERB
admet-3065	337	28	targeted	targeted	ADJ
admet-3065	337	29	delivery	delivery	NOUN
admet-3065	337	30	[	[	X
admet-3065	337	31	194,195	194,195	NUM
admet-3065	337	32	]	]	PUNCT
admet-3065	337	33	.	.	PUNCT
admet-3065	338	1	for	for	ADP
admet-3065	338	2	instance	instance	NOUN
admet-3065	338	3	,	,	PUNCT
admet-3065	338	4	a	a	DET
admet-3065	338	5	cyclic	cyclic	ADJ
admet-3065	338	6	arginine	arginine	NOUN
admet-3065	338	7	-	-	PUNCT
admet-3065	338	8	glycine	glycine	NOUN
admet-3065	338	9	-	-	PUNCT
admet-3065	338	10	aspartic	aspartic	ADJ
admet-3065	338	11	acid	acid	NOUN
admet-3065	338	12	-	-	PUNCT
admet-3065	338	13	tyrosine	tyrosine	NOUN
admet-3065	338	14	-	-	PUNCT
admet-3065	338	15	lysine	lysine	NOUN
admet-3065	338	16	peptide	peptide	NOUN
admet-3065	338	17	(	(	PUNCT
admet-3065	338	18	crgdyk	crgdyk	NOUN
admet-3065	338	19	)	)	PUNCT
admet-3065	338	20	was	be	AUX
admet-3065	338	21	used	use	VERB
admet-3065	338	22	to	to	PART
admet-3065	338	23	target	target	VERB
admet-3065	338	24	αvβ3	αvβ3	NOUN
admet-3065	338	25	integrin	integrin	NOUN
admet-3065	338	26	,	,	PUNCT
admet-3065	338	27	a	a	DET
admet-3065	338	28	receptor	receptor	NOUN
admet-3065	338	29	overexpressed	overexpresse	VERB
admet-3065	338	30	in	in	ADP
admet-3065	338	31	bone	bone	NOUN
admet-3065	338	32	metastasis	metastasis	NOUN
admet-3065	338	33	[	[	X
admet-3065	338	34	196,197	196,197	NUM
admet-3065	338	35	]	]	PUNCT
admet-3065	338	36	.	.	PUNCT
admet-3065	339	1	crgdyk	crgdyk	NOUN
admet-3065	339	2	-	-	PUNCT
admet-3065	339	3	conjugated	conjugate	VERB
admet-3065	339	4	liposomes	liposome	NOUN
admet-3065	339	5	exhibited	exhibit	VERB
admet-3065	339	6	more	more	ADJ
admet-3065	339	7	than	than	ADP
admet-3065	339	8	threefold	threefold	ADV
admet-3065	339	9	higher	high	ADJ
admet-3065	339	10	tumour	tumour	NOUN
admet-3065	339	11	cell	cell	NOUN
admet-3065	339	12	internalization	internalization	NOUN
admet-3065	339	13	rates	rate	NOUN
admet-3065	339	14	and	and	CCONJ
admet-3065	339	15	were	be	AUX
admet-3065	339	16	more	more	ADJ
admet-3065	339	17	than	than	ADP
admet-3065	339	18	88	88	NUM
admet-3065	339	19	%	%	NOUN
admet-3065	339	20	more	more	ADV
admet-3065	339	21	cytotoxic	cytotoxic	ADJ
admet-3065	339	22	than	than	ADP
admet-3065	339	23	free	free	ADJ
admet-3065	339	24	drugs	drug	NOUN
admet-3065	339	25	[	[	X
admet-3065	339	26	198	198	NUM
admet-3065	339	27	]	]	PUNCT
admet-3065	339	28	.	.	PUNCT
admet-3065	340	1	despite	despite	SCONJ
admet-3065	340	2	their	their	PRON
admet-3065	340	3	promise	promise	NOUN
admet-3065	340	4	,	,	PUNCT
admet-3065	340	5	challenges	challenge	NOUN
admet-3065	340	6	such	such	ADJ
admet-3065	340	7	as	as	ADP
admet-3065	340	8	defining	define	VERB
admet-3065	340	9	peptide	peptide	ADJ
admet-3065	340	10	density	density	NOUN
admet-3065	340	11	and	and	CCONJ
admet-3065	340	12	storage	storage	NOUN
admet-3065	340	13	stability	stability	NOUN
admet-3065	340	14	remain	remain	VERB
admet-3065	340	15	[	[	X
admet-3065	340	16	199,200	199,200	NUM
admet-3065	340	17	]	]	PUNCT
admet-3065	340	18	.	.	PUNCT
admet-3065	341	1	folate	folate	NOUN
admet-3065	341	2	folate	folate	NOUN
admet-3065	341	3	,	,	PUNCT
admet-3065	341	4	or	or	CCONJ
admet-3065	341	5	vitamin	vitamin	NOUN
admet-3065	341	6	b9	b9	NOUN
admet-3065	341	7	,	,	PUNCT
admet-3065	341	8	plays	play	VERB
admet-3065	341	9	a	a	DET
admet-3065	341	10	role	role	NOUN
admet-3065	341	11	in	in	ADP
admet-3065	341	12	both	both	CCONJ
admet-3065	341	13	the	the	DET
admet-3065	341	14	onset	onset	NOUN
admet-3065	341	15	and	and	CCONJ
admet-3065	341	16	growth	growth	NOUN
admet-3065	341	17	of	of	ADP
admet-3065	341	18	cancer	cancer	NOUN
admet-3065	341	19	[	[	X
admet-3065	341	20	201,202	201,202	NUM
admet-3065	341	21	]	]	PUNCT
admet-3065	341	22	.	.	PUNCT
admet-3065	342	1	tumour	tumour	NOUN
admet-3065	342	2	cells	cell	NOUN
admet-3065	342	3	that	that	PRON
admet-3065	342	4	undergo	undergo	VERB
admet-3065	342	5	rapid	rapid	ADJ
admet-3065	342	6	proliferation	proliferation	NOUN
admet-3065	342	7	have	have	VERB
admet-3065	342	8	a	a	DET
admet-3065	342	9	high	high	ADJ
admet-3065	342	10	requirement	requirement	NOUN
admet-3065	342	11	for	for	ADP
admet-3065	342	12	dna	dna	ADJ
admet-3065	342	13	synthesis	synthesis	NOUN
admet-3065	342	14	and	and	CCONJ
admet-3065	342	15	are	be	AUX
admet-3065	342	16	prone	prone	ADJ
admet-3065	342	17	to	to	ADP
admet-3065	342	18	overexpression	overexpression	NOUN
admet-3065	342	19	folate	folate	NOUN
admet-3065	342	20	receptors	receptor	NOUN
admet-3065	342	21	[	[	X
admet-3065	342	22	203,204	203,204	NUM
admet-3065	342	23	]	]	PUNCT
admet-3065	342	24	.	.	PUNCT
admet-3065	343	1	as	as	ADP
admet-3065	343	2	a	a	DET
admet-3065	343	3	result	result	NOUN
admet-3065	343	4	,	,	PUNCT
admet-3065	343	5	folate	folate	NOUN
admet-3065	343	6	receptors	receptor	NOUN
admet-3065	343	7	have	have	AUX
admet-3065	343	8	become	become	VERB
admet-3065	343	9	an	an	DET
admet-3065	343	10	attractive	attractive	ADJ
admet-3065	343	11	target	target	NOUN
admet-3065	343	12	in	in	ADP
admet-3065	343	13	cancer	cancer	NOUN
admet-3065	343	14	therapies	therapy	NOUN
admet-3065	343	15	[	[	X
admet-3065	343	16	205	205	NUM
admet-3065	343	17	]	]	PUNCT
admet-3065	343	18	.	.	PUNCT
admet-3065	344	1	folate	folate	NOUN
admet-3065	344	2	can	can	AUX
admet-3065	344	3	be	be	AUX
admet-3065	344	4	conjugated	conjugate	VERB
admet-3065	344	5	to	to	ADP
admet-3065	344	6	liposomes	liposome	NOUN
admet-3065	344	7	to	to	PART
admet-3065	344	8	target	target	VERB
admet-3065	344	9	these	these	DET
admet-3065	344	10	overexpressed	overexpresse	VERB
admet-3065	344	11	receptors	receptor	NOUN
admet-3065	344	12	[	[	X
admet-3065	344	13	206	206	NUM
admet-3065	344	14	]	]	PUNCT
admet-3065	344	15	.	.	PUNCT
admet-3065	345	1	numerous	numerous	ADJ
admet-3065	345	2	investigations	investigation	NOUN
admet-3065	345	3	e.	e.	PROPN
admet-3065	345	4	j.	j.	PROPN
admet-3065	345	5	saleh	saleh	PROPN
admet-3065	345	6	et	et	PROPN
admet-3065	345	7	al	al	PROPN
admet-3065	345	8	.	.	PROPN
admet-3065	345	9	admet	admet	PROPN
admet-3065	345	10	&	&	CCONJ
admet-3065	345	11	dmpk	dmpk	PROPN
admet-3065	345	12	00(0	00(0	PROPN
admet-3065	345	13	)	)	PUNCT
admet-3065	345	14	(	(	PUNCT
admet-3065	345	15	2025	2025	NUM
admet-3065	345	16	)	)	PUNCT
admet-3065	345	17	3065	3065	NUM
admet-3065	345	18	16	16	NUM
admet-3065	345	19	have	have	AUX
admet-3065	345	20	demonstrated	demonstrate	VERB
admet-3065	345	21	that	that	SCONJ
admet-3065	345	22	folate	folate	NOUN
admet-3065	345	23	-	-	PUNCT
admet-3065	345	24	conjugated	conjugate	VERB
admet-3065	345	25	liposomes	liposome	NOUN
admet-3065	345	26	exhibit	exhibit	VERB
admet-3065	345	27	increased	increase	VERB
admet-3065	345	28	cellular	cellular	ADJ
admet-3065	345	29	uptake	uptake	NOUN
admet-3065	345	30	and	and	CCONJ
admet-3065	345	31	improved	improve	VERB
admet-3065	345	32	specificity	specificity	NOUN
admet-3065	345	33	in	in	ADP
admet-3065	345	34	vitro	vitro	X
admet-3065	345	35	[	[	X
admet-3065	345	36	206,207	206,207	NUM
admet-3065	345	37	]	]	PUNCT
admet-3065	345	38	.	.	PUNCT
admet-3065	346	1	however	however	ADV
admet-3065	346	2	,	,	PUNCT
admet-3065	346	3	challenges	challenge	NOUN
admet-3065	346	4	remain	remain	VERB
admet-3065	346	5	regarding	regard	VERB
admet-3065	346	6	their	their	PRON
admet-3065	346	7	in	in	ADP
admet-3065	346	8	vivo	vivo	NOUN
admet-3065	346	9	behaviour	behaviour	NOUN
admet-3065	346	10	,	,	PUNCT
admet-3065	346	11	as	as	SCONJ
admet-3065	346	12	some	some	DET
admet-3065	346	13	studies	study	NOUN
admet-3065	346	14	show	show	VERB
admet-3065	346	15	that	that	SCONJ
admet-3065	346	16	intravenous	intravenous	ADJ
admet-3065	346	17	administration	administration	NOUN
admet-3065	346	18	is	be	AUX
admet-3065	346	19	not	not	PART
admet-3065	346	20	much	much	ADV
admet-3065	346	21	more	more	ADV
admet-3065	346	22	effective	effective	ADJ
admet-3065	346	23	at	at	ADP
admet-3065	346	24	increasing	increase	VERB
admet-3065	346	25	drug	drug	NOUN
admet-3065	346	26	uptake	uptake	ADJ
admet-3065	346	27	in	in	ADP
admet-3065	346	28	tumours	tumour	NOUN
admet-3065	346	29	than	than	ADP
admet-3065	346	30	control	control	NOUN
admet-3065	346	31	liposomes	liposome	NOUN
admet-3065	346	32	,	,	PUNCT
admet-3065	346	33	and	and	CCONJ
admet-3065	346	34	that	that	SCONJ
admet-3065	346	35	poor	poor	ADJ
admet-3065	346	36	drug	drug	NOUN
admet-3065	346	37	unloading	unloading	NOUN
admet-3065	346	38	at	at	ADP
admet-3065	346	39	the	the	DET
admet-3065	346	40	target	target	NOUN
admet-3065	346	41	site	site	NOUN
admet-3065	346	42	can	can	AUX
admet-3065	346	43	compromise	compromise	VERB
admet-3065	346	44	efficacy	efficacy	NOUN
admet-3065	346	45	[	[	X
admet-3065	346	46	208,209	208,209	NUM
admet-3065	346	47	]	]	PUNCT
admet-3065	346	48	.	.	PUNCT
admet-3065	347	1	aptamers	aptamer	NOUN
admet-3065	347	2	aptamers	aptamer	NOUN
admet-3065	347	3	are	be	AUX
admet-3065	347	4	single	single	ADJ
admet-3065	347	5	-	-	PUNCT
admet-3065	347	6	stranded	strand	VERB
admet-3065	347	7	rna	rna	NOUN
admet-3065	347	8	or	or	CCONJ
admet-3065	347	9	dna	dna	PROPN
admet-3065	347	10	molecules	molecule	NOUN
admet-3065	347	11	that	that	PRON
admet-3065	347	12	have	have	VERB
admet-3065	347	13	a	a	DET
admet-3065	347	14	defined	define	VERB
admet-3065	347	15	three	three	NUM
admet-3065	347	16	-	-	PUNCT
admet-3065	347	17	dimensional	dimensional	ADJ
admet-3065	347	18	structure	structure	NOUN
admet-3065	347	19	and	and	CCONJ
admet-3065	347	20	the	the	DET
admet-3065	347	21	capacity	capacity	NOUN
admet-3065	347	22	to	to	PART
admet-3065	347	23	bind	bind	VERB
admet-3065	347	24	selectively	selectively	ADV
admet-3065	347	25	to	to	PART
admet-3065	347	26	target	target	VERB
admet-3065	347	27	molecules	molecule	NOUN
admet-3065	347	28	[	[	X
admet-3065	347	29	210	210	NUM
admet-3065	347	30	]	]	PUNCT
admet-3065	347	31	.	.	PUNCT
admet-3065	348	1	hailed	hail	VERB
admet-3065	348	2	as	as	ADP
admet-3065	348	3	"	"	PUNCT
admet-3065	348	4	chemical	chemical	NOUN
admet-3065	348	5	antibodies	antibodie	VERB
admet-3065	348	6	,	,	PUNCT
admet-3065	348	7	"	"	PUNCT
admet-3065	348	8	aptamers	aptamer	NOUN
admet-3065	348	9	offer	offer	VERB
admet-3065	348	10	high	high	ADJ
admet-3065	348	11	specificity	specificity	NOUN
admet-3065	348	12	,	,	PUNCT
admet-3065	348	13	stability	stability	NOUN
admet-3065	348	14	,	,	PUNCT
admet-3065	348	15	and	and	CCONJ
admet-3065	348	16	low	low	ADJ
admet-3065	348	17	immunogenicity	immunogenicity	NOUN
admet-3065	348	18	[	[	X
admet-3065	348	19	211	211	NUM
admet-3065	348	20	-	-	SYM
admet-3065	348	21	213	213	NUM
admet-3065	348	22	]	]	PUNCT
admet-3065	348	23	.	.	PUNCT
admet-3065	349	1	this	this	DET
admet-3065	349	2	selectivity	selectivity	NOUN
admet-3065	349	3	makes	make	VERB
admet-3065	349	4	aptamers	aptamer	NOUN
admet-3065	349	5	a	a	DET
admet-3065	349	6	strong	strong	ADJ
admet-3065	349	7	candidate	candidate	NOUN
admet-3065	349	8	for	for	ADP
admet-3065	349	9	the	the	DET
admet-3065	349	10	development	development	NOUN
admet-3065	349	11	of	of	ADP
admet-3065	349	12	targeted	target	VERB
admet-3065	349	13	drug	drug	NOUN
admet-3065	349	14	-	-	PUNCT
admet-3065	349	15	delivery	delivery	NOUN
admet-3065	349	16	vectors	vector	NOUN
admet-3065	349	17	[	[	X
admet-3065	349	18	214,215	214,215	NUM
admet-3065	349	19	]	]	PUNCT
admet-3065	349	20	.	.	PUNCT
admet-3065	350	1	researchers	researcher	NOUN
admet-3065	350	2	have	have	AUX
admet-3065	350	3	utilized	utilize	VERB
admet-3065	350	4	aptamer	aptamer	NOUN
admet-3065	350	5	-	-	PUNCT
admet-3065	350	6	conjugated	conjugate	VERB
admet-3065	350	7	liposomes	liposome	NOUN
admet-3065	350	8	to	to	PART
admet-3065	350	9	deliver	deliver	VERB
admet-3065	350	10	drugs	drug	NOUN
admet-3065	350	11	to	to	ADP
admet-3065	350	12	a	a	DET
admet-3065	350	13	wide	wide	ADJ
admet-3065	350	14	variety	variety	NOUN
admet-3065	350	15	of	of	ADP
admet-3065	350	16	tissues	tissue	NOUN
admet-3065	350	17	,	,	PUNCT
admet-3065	350	18	including	include	VERB
admet-3065	350	19	cancer	cancer	NOUN
admet-3065	350	20	cells	cell	NOUN
admet-3065	350	21	,	,	PUNCT
admet-3065	350	22	corneal	corneal	ADJ
admet-3065	350	23	cells	cell	NOUN
admet-3065	350	24	,	,	PUNCT
admet-3065	350	25	and	and	CCONJ
admet-3065	350	26	muscle	muscle	NOUN
admet-3065	350	27	tissue	tissue	NOUN
admet-3065	351	1	[	[	X
admet-3065	351	2	212,216	212,216	NUM
admet-3065	351	3	]	]	PUNCT
admet-3065	351	4	.	.	PUNCT
admet-3065	352	1	compared	compare	VERB
admet-3065	352	2	with	with	ADP
admet-3065	352	3	antibody	antibody	NOUN
admet-3065	352	4	-	-	PUNCT
admet-3065	352	5	conjugated	conjugate	VERB
admet-3065	352	6	liposomes	liposome	NOUN
admet-3065	352	7	,	,	PUNCT
admet-3065	352	8	aptamer	aptamer	NOUN
admet-3065	352	9	-	-	PUNCT
admet-3065	352	10	conjugated	conjugate	VERB
admet-3065	352	11	liposomes	liposome	NOUN
admet-3065	352	12	have	have	AUX
admet-3065	352	13	shown	show	VERB
admet-3065	352	14	better	well	ADJ
admet-3065	352	15	performance	performance	NOUN
admet-3065	352	16	in	in	ADP
admet-3065	352	17	some	some	PRON
admet-3065	352	18	in	in	ADP
admet-3065	352	19	vivo	vivo	ADJ
admet-3065	352	20	tests	test	NOUN
admet-3065	352	21	,	,	PUNCT
admet-3065	352	22	stimulating	stimulate	VERB
admet-3065	352	23	growing	grow	VERB
admet-3065	352	24	interest	interest	NOUN
admet-3065	352	25	in	in	ADP
admet-3065	352	26	their	their	PRON
admet-3065	352	27	use	use	NOUN
admet-3065	352	28	[	[	X
admet-3065	352	29	216	216	NUM
admet-3065	352	30	]	]	PUNCT
admet-3065	352	31	.	.	PUNCT
admet-3065	353	1	types	type	NOUN
admet-3065	353	2	of	of	ADP
admet-3065	353	3	genetic	genetic	ADJ
admet-3065	353	4	cargo	cargo	NOUN
admet-3065	353	5	and	and	CCONJ
admet-3065	353	6	delivery	delivery	NOUN
admet-3065	353	7	strategies	strategy	NOUN
admet-3065	353	8	dna	dna	NOUN
admet-3065	353	9	and	and	CCONJ
admet-3065	353	10	mrna	mrna	PROPN
admet-3065	353	11	delivery	delivery	NOUN
admet-3065	353	12	targeted	target	VERB
admet-3065	353	13	and	and	CCONJ
admet-3065	353	14	efficient	efficient	ADJ
admet-3065	353	15	delivery	delivery	NOUN
admet-3065	353	16	of	of	ADP
admet-3065	353	17	therapeutic	therapeutic	ADJ
admet-3065	353	18	genetic	genetic	ADJ
admet-3065	353	19	material	material	NOUN
admet-3065	353	20	is	be	AUX
admet-3065	353	21	a	a	DET
admet-3065	353	22	cornerstone	cornerstone	NOUN
admet-3065	353	23	of	of	ADP
admet-3065	353	24	progress	progress	NOUN
admet-3065	353	25	in	in	ADP
admet-3065	353	26	cancer	cancer	NOUN
admet-3065	353	27	gene	gene	NOUN
admet-3065	353	28	therapy	therapy	NOUN
admet-3065	353	29	[	[	X
admet-3065	353	30	217	217	NUM
admet-3065	353	31	]	]	PUNCT
admet-3065	353	32	.	.	PUNCT
admet-3065	354	1	liposomes	liposome	NOUN
admet-3065	354	2	are	be	AUX
admet-3065	354	3	a	a	DET
admet-3065	354	4	highly	highly	ADV
admet-3065	354	5	promising	promising	ADJ
admet-3065	354	6	vehicle	vehicle	NOUN
admet-3065	354	7	for	for	ADP
admet-3065	354	8	delivering	deliver	VERB
admet-3065	354	9	both	both	DET
admet-3065	354	10	dna	dna	NOUN
admet-3065	354	11	and	and	CCONJ
admet-3065	354	12	mrna	mrna	PROPN
admet-3065	355	1	[	[	X
admet-3065	355	2	218	218	NUM
admet-3065	355	3	]	]	PUNCT
admet-3065	355	4	.	.	PUNCT
admet-3065	356	1	both	both	PRON
admet-3065	356	2	are	be	AUX
admet-3065	356	3	effectively	effectively	ADV
admet-3065	356	4	stabilized	stabilize	VERB
admet-3065	356	5	and	and	CCONJ
admet-3065	356	6	protected	protect	VERB
admet-3065	356	7	against	against	ADP
admet-3065	356	8	nuclease	nuclease	NOUN
admet-3065	356	9	degradation	degradation	NOUN
admet-3065	356	10	through	through	ADP
admet-3065	356	11	complexation	complexation	NOUN
admet-3065	356	12	with	with	ADP
admet-3065	356	13	cationic	cationic	ADJ
admet-3065	356	14	lipids	lipid	NOUN
admet-3065	356	15	that	that	PRON
admet-3065	356	16	enable	enable	VERB
admet-3065	356	17	them	they	PRON
admet-3065	356	18	to	to	PART
admet-3065	356	19	be	be	AUX
admet-3065	356	20	internalized	internalize	VERB
admet-3065	356	21	by	by	ADP
admet-3065	356	22	target	target	NOUN
admet-3065	356	23	cells	cell	NOUN
admet-3065	356	24	[	[	X
admet-3065	356	25	219,220	219,220	NUM
admet-3065	356	26	]	]	PUNCT
admet-3065	356	27	.	.	PUNCT
admet-3065	357	1	encapsulation	encapsulation	NOUN
admet-3065	357	2	strategies	strategy	NOUN
admet-3065	357	3	not	not	PART
admet-3065	357	4	only	only	ADV
admet-3065	357	5	protect	protect	VERB
admet-3065	357	6	dna	dna	NOUN
admet-3065	357	7	from	from	ADP
admet-3065	357	8	enzyme	enzyme	NOUN
admet-3065	357	9	degradation	degradation	NOUN
admet-3065	357	10	and	and	CCONJ
admet-3065	357	11	immune	immune	ADJ
admet-3065	357	12	recognition	recognition	NOUN
admet-3065	357	13	but	but	CCONJ
admet-3065	357	14	also	also	ADV
admet-3065	357	15	maintain	maintain	VERB
admet-3065	357	16	the	the	DET
admet-3065	357	17	structural	structural	ADJ
admet-3065	357	18	integrity	integrity	NOUN
admet-3065	357	19	of	of	ADP
admet-3065	357	20	genetic	genetic	ADJ
admet-3065	357	21	material	material	NOUN
admet-3065	357	22	in	in	ADP
admet-3065	357	23	transit	transit	NOUN
admet-3065	357	24	[	[	X
admet-3065	357	25	221	221	NUM
admet-3065	357	26	]	]	PUNCT
admet-3065	357	27	.	.	PUNCT
admet-3065	358	1	recent	recent	ADJ
admet-3065	358	2	developments	development	NOUN
admet-3065	358	3	have	have	AUX
admet-3065	358	4	also	also	ADV
admet-3065	358	5	highlighted	highlight	VERB
admet-3065	358	6	the	the	DET
admet-3065	358	7	potential	potential	NOUN
admet-3065	358	8	of	of	ADP
admet-3065	358	9	mrna	mrna	PROPN
admet-3065	358	10	therapies	therapy	NOUN
admet-3065	358	11	,	,	PUNCT
admet-3065	358	12	particularly	particularly	ADV
admet-3065	358	13	cancer	cancer	NOUN
admet-3065	358	14	vaccines	vaccine	NOUN
admet-3065	358	15	encoding	encode	VERB
admet-3065	358	16	tumour	tumour	NOUN
admet-3065	358	17	-	-	PUNCT
admet-3065	358	18	specific	specific	ADJ
admet-3065	358	19	antigens	antigen	NOUN
admet-3065	358	20	to	to	PART
admet-3065	358	21	elicit	elicit	VERB
admet-3065	358	22	strong	strong	ADJ
admet-3065	358	23	immune	immune	ADJ
admet-3065	358	24	responses	response	NOUN
admet-3065	358	25	[	[	X
admet-3065	358	26	222	222	NUM
admet-3065	358	27	]	]	PUNCT
admet-3065	358	28	.	.	PUNCT
admet-3065	359	1	the	the	DET
admet-3065	359	2	rapid	rapid	ADJ
admet-3065	359	3	development	development	NOUN
admet-3065	359	4	and	and	CCONJ
admet-3065	359	5	regulatory	regulatory	ADJ
admet-3065	359	6	approval	approval	NOUN
admet-3065	359	7	of	of	ADP
admet-3065	359	8	mrna	mrna	PROPN
admet-3065	359	9	vaccines	vaccine	NOUN
admet-3065	359	10	during	during	ADP
admet-3065	359	11	the	the	DET
admet-3065	359	12	covid-19	covid-19	PROPN
admet-3065	359	13	pandemic	pandemic	NOUN
admet-3065	359	14	have	have	AUX
admet-3065	359	15	accelerated	accelerate	VERB
admet-3065	359	16	research	research	NOUN
admet-3065	359	17	into	into	ADP
admet-3065	359	18	mrna	mrna	PROPN
admet-3065	359	19	cancer	cancer	NOUN
admet-3065	359	20	vaccines	vaccine	NOUN
admet-3065	359	21	[	[	X
admet-3065	359	22	223	223	NUM
admet-3065	359	23	]	]	PUNCT
admet-3065	359	24	.	.	PUNCT
admet-3065	360	1	sirna	sirna	PROPN
admet-3065	360	2	delivery	delivery	PROPN
admet-3065	360	3	rna	rna	PROPN
admet-3065	360	4	interference	interference	NOUN
admet-3065	360	5	(	(	PUNCT
admet-3065	360	6	rnai	rnai	PROPN
admet-3065	360	7	)	)	PUNCT
admet-3065	360	8	,	,	PUNCT
admet-3065	360	9	as	as	SCONJ
admet-3065	360	10	mediated	mediate	VERB
admet-3065	360	11	by	by	ADP
admet-3065	360	12	small	small	ADJ
admet-3065	360	13	interfering	interfere	VERB
admet-3065	360	14	rna	rna	PROPN
admet-3065	360	15	(	(	PUNCT
admet-3065	360	16	sirna	sirna	PROPN
admet-3065	360	17	)	)	PUNCT
admet-3065	360	18	,	,	PUNCT
admet-3065	360	19	enables	enable	VERB
admet-3065	360	20	post	post	ADJ
admet-3065	360	21	-	-	ADJ
admet-3065	360	22	transcriptional	transcriptional	ADJ
admet-3065	360	23	gene	gene	NOUN
admet-3065	360	24	silencing	silence	VERB
admet-3065	360	25	by	by	ADP
admet-3065	360	26	inducing	induce	VERB
admet-3065	360	27	target	target	NOUN
admet-3065	360	28	mrna	mrna	NOUN
admet-3065	360	29	degradation	degradation	NOUN
admet-3065	360	30	or	or	CCONJ
admet-3065	360	31	preventing	prevent	VERB
admet-3065	360	32	its	its	PRON
admet-3065	360	33	translation	translation	NOUN
admet-3065	360	34	[	[	X
admet-3065	360	35	224,225	224,225	NUM
admet-3065	360	36	]	]	X
admet-3065	360	37	.	.	PUNCT
admet-3065	361	1	typically	typically	ADV
admet-3065	361	2	,	,	PUNCT
admet-3065	361	3	sirnas	sirna	NOUN
admet-3065	361	4	are	be	AUX
admet-3065	361	5	21	21	NUM
admet-3065	361	6	to	to	PART
admet-3065	361	7	23	23	NUM
admet-3065	361	8	nucleotides	nucleotide	NOUN
admet-3065	361	9	in	in	ADP
admet-3065	361	10	length	length	NOUN
admet-3065	361	11	[	[	X
admet-3065	361	12	226	226	NUM
admet-3065	361	13	]	]	PUNCT
admet-3065	361	14	.	.	PUNCT
admet-3065	362	1	while	while	SCONJ
admet-3065	362	2	it	it	PRON
admet-3065	362	3	shows	show	VERB
admet-3065	362	4	promise	promise	NOUN
admet-3065	362	5	as	as	ADP
admet-3065	362	6	a	a	DET
admet-3065	362	7	therapeutic	therapeutic	ADJ
admet-3065	362	8	agent	agent	NOUN
admet-3065	362	9	,	,	PUNCT
admet-3065	362	10	the	the	DET
admet-3065	362	11	clinical	clinical	ADJ
admet-3065	362	12	application	application	NOUN
admet-3065	362	13	of	of	ADP
admet-3065	362	14	sirna	sirna	PROPN
admet-3065	362	15	is	be	AUX
admet-3065	362	16	limited	limit	VERB
admet-3065	362	17	by	by	ADP
admet-3065	362	18	rapid	rapid	ADJ
admet-3065	362	19	nuclease	nuclease	NOUN
admet-3065	362	20	-	-	PUNCT
admet-3065	362	21	mediated	mediate	VERB
admet-3065	362	22	degradation	degradation	NOUN
admet-3065	362	23	,	,	PUNCT
admet-3065	362	24	uptake	uptake	ADJ
admet-3065	362	25	by	by	ADP
admet-3065	362	26	immune	immune	ADJ
admet-3065	362	27	cells	cell	NOUN
admet-3065	362	28	,	,	PUNCT
admet-3065	362	29	and	and	CCONJ
admet-3065	362	30	poor	poor	ADJ
admet-3065	362	31	tissue	tissue	NOUN
admet-3065	362	32	penetration	penetration	NOUN
admet-3065	362	33	[	[	X
admet-3065	362	34	227	227	NUM
admet-3065	362	35	]	]	PUNCT
admet-3065	362	36	.	.	PUNCT
admet-3065	363	1	to	to	PART
admet-3065	363	2	overcome	overcome	VERB
admet-3065	363	3	these	these	DET
admet-3065	363	4	limitations	limitation	NOUN
admet-3065	363	5	,	,	PUNCT
admet-3065	363	6	nanocarrier	nanocarrier	NOUN
admet-3065	363	7	-	-	PUNCT
admet-3065	363	8	mediated	mediate	VERB
admet-3065	363	9	delivery	delivery	NOUN
admet-3065	363	10	vectors	vector	NOUN
admet-3065	363	11	have	have	AUX
admet-3065	363	12	been	be	AUX
admet-3065	363	13	developed	develop	VERB
admet-3065	363	14	.	.	PUNCT
admet-3065	364	1	of	of	ADP
admet-3065	364	2	these	these	PRON
admet-3065	364	3	,	,	PUNCT
admet-3065	364	4	liposomes	liposome	NOUN
admet-3065	364	5	have	have	AUX
admet-3065	364	6	emerged	emerge	VERB
admet-3065	364	7	as	as	ADP
admet-3065	364	8	promising	promising	ADJ
admet-3065	364	9	candidates	candidate	NOUN
admet-3065	364	10	,	,	PUNCT
admet-3065	364	11	enabling	enable	VERB
admet-3065	364	12	sirna	sirna	PROPN
admet-3065	364	13	entry	entry	NOUN
admet-3065	364	14	into	into	ADP
admet-3065	364	15	tumour	tumour	ADJ
admet-3065	364	16	cells	cell	NOUN
admet-3065	364	17	through	through	ADP
admet-3065	364	18	various	various	ADJ
admet-3065	364	19	endocytic	endocytic	ADJ
admet-3065	364	20	processes	process	NOUN
admet-3065	364	21	,	,	PUNCT
admet-3065	364	22	including	include	VERB
admet-3065	364	23	clathrin	clathrin	NOUN
admet-3065	364	24	-	-	PUNCT
admet-3065	364	25	mediated	mediate	VERB
admet-3065	364	26	endocytosis	endocytosis	NOUN
admet-3065	364	27	,	,	PUNCT
admet-3065	364	28	macropinocytosis	macropinocytosis	NOUN
admet-3065	364	29	,	,	PUNCT
admet-3065	364	30	and	and	CCONJ
admet-3065	364	31	cholesterol	cholesterol	NOUN
admet-3065	364	32	-	-	PUNCT
admet-3065	364	33	dependent	dependent	ADJ
admet-3065	364	34	membrane	membrane	NOUN
admet-3065	364	35	transport	transport	NOUN
admet-3065	364	36	[	[	X
admet-3065	364	37	228,229	228,229	NUM
admet-3065	364	38	]	]	PUNCT
admet-3065	364	39	.	.	PUNCT
admet-3065	365	1	shrna	shrna	ADJ
admet-3065	365	2	delivery	delivery	PROPN
admet-3065	365	3	short	short	ADJ
admet-3065	365	4	hairpin	hairpin	NOUN
admet-3065	365	5	rnas	rna	NOUN
admet-3065	365	6	(	(	PUNCT
admet-3065	365	7	shrnas	shrnas	PROPN
admet-3065	365	8	)	)	PUNCT
admet-3065	365	9	are	be	AUX
admet-3065	365	10	another	another	DET
admet-3065	365	11	form	form	NOUN
admet-3065	365	12	of	of	ADP
admet-3065	365	13	genetic	genetic	ADJ
admet-3065	365	14	agents	agent	NOUN
admet-3065	365	15	used	use	VERB
admet-3065	365	16	for	for	ADP
admet-3065	365	17	cancer	cancer	NOUN
admet-3065	365	18	treatment	treatment	NOUN
admet-3065	365	19	[	[	X
admet-3065	365	20	230,231	230,231	NUM
admet-3065	365	21	]	]	PUNCT
admet-3065	365	22	.	.	PUNCT
admet-3065	366	1	as	as	ADP
admet-3065	366	2	members	member	NOUN
admet-3065	366	3	of	of	ADP
admet-3065	366	4	the	the	DET
admet-3065	366	5	short	short	ADJ
admet-3065	366	6	non	non	ADJ
admet-3065	366	7	-	-	ADJ
admet-3065	366	8	coding	coding	ADJ
admet-3065	366	9	rna	rna	NOUN
admet-3065	366	10	(	(	PUNCT
admet-3065	366	11	ncrna	ncrna	NOUN
admet-3065	366	12	)	)	PUNCT
admet-3065	366	13	family	family	NOUN
admet-3065	366	14	,	,	PUNCT
admet-3065	366	15	shrnas	shrnas	PROPN
admet-3065	366	16	behave	behave	VERB
admet-3065	366	17	similarly	similarly	ADV
admet-3065	366	18	to	to	ADP
admet-3065	366	19	sirnas	sirna	NOUN
admet-3065	366	20	in	in	ADP
admet-3065	366	21	repressing	repress	VERB
admet-3065	366	22	gene	gene	NOUN
admet-3065	366	23	expression	expression	NOUN
admet-3065	366	24	through	through	ADP
admet-3065	366	25	rna	rna	NOUN
admet-3065	366	26	interference	interference	NOUN
admet-3065	366	27	-	-	PUNCT
admet-3065	366	28	mediated	mediate	VERB
admet-3065	366	29	gene	gene	NOUN
admet-3065	366	30	knockdown	knockdown	NOUN
admet-3065	367	1	[	[	X
admet-3065	367	2	232	232	NUM
admet-3065	367	3	]	]	PUNCT
admet-3065	367	4	.	.	PUNCT
admet-3065	368	1	following	follow	VERB
admet-3065	368	2	delivery	delivery	NOUN
admet-3065	368	3	into	into	ADP
admet-3065	368	4	cells	cell	NOUN
admet-3065	368	5	,	,	PUNCT
admet-3065	368	6	usually	usually	ADV
admet-3065	368	7	via	via	ADP
admet-3065	368	8	a	a	DET
admet-3065	368	9	vector	vector	NOUN
admet-3065	368	10	,	,	PUNCT
admet-3065	368	11	shrnas	shrnas	PROPN
admet-3065	368	12	are	be	AUX
admet-3065	368	13	transcribed	transcribe	VERB
admet-3065	368	14	within	within	ADP
admet-3065	368	15	the	the	DET
admet-3065	368	16	nucleus	nucleus	NOUN
admet-3065	368	17	and	and	CCONJ
admet-3065	368	18	subsequently	subsequently	ADV
admet-3065	368	19	form	form	VERB
admet-3065	368	20	hairpins	hairpin	NOUN
admet-3065	368	21	[	[	X
admet-3065	368	22	232,233	232,233	NUM
admet-3065	368	23	]	]	PUNCT
admet-3065	368	24	.	.	PUNCT
admet-3065	369	1	these	these	DET
admet-3065	369	2	hairpin	hairpin	ADJ
admet-3065	369	3	rnas	rna	NOUN
admet-3065	369	4	are	be	AUX
admet-3065	369	5	then	then	ADV
admet-3065	369	6	exported	export	VERB
admet-3065	369	7	to	to	ADP
admet-3065	369	8	the	the	DET
admet-3065	369	9	cytoplasm	cytoplasm	NOUN
admet-3065	369	10	,	,	PUNCT
admet-3065	369	11	where	where	SCONJ
admet-3065	369	12	the	the	DET
admet-3065	369	13	enzyme	enzyme	NOUN
admet-3065	369	14	dicer	dicer	NOUN
admet-3065	369	15	cleaves	cleave	VERB
admet-3065	369	16	them	they	PRON
admet-3065	369	17	into	into	ADP
admet-3065	369	18	sirna	sirna	PROPN
admet-3065	369	19	-	-	PUNCT
admet-3065	369	20	like	like	ADJ
admet-3065	369	21	molecules	molecule	NOUN
admet-3065	369	22	,	,	PUNCT
admet-3065	369	23	which	which	PRON
admet-3065	369	24	are	be	AUX
admet-3065	369	25	then	then	ADV
admet-3065	369	26	loaded	load	VERB
admet-3065	369	27	into	into	ADP
admet-3065	369	28	the	the	DET
admet-3065	369	29	rna	rna	NOUN
admet-3065	369	30	-	-	PUNCT
admet-3065	369	31	induced	induced	ADJ
admet-3065	369	32	silencing	silence	VERB
admet-3065	369	33	complex	complex	NOUN
admet-3065	369	34	(	(	PUNCT
admet-3065	369	35	risc	risc	PROPN
admet-3065	369	36	)	)	PUNCT
admet-3065	369	37	to	to	PART
admet-3065	369	38	guide	guide	VERB
admet-3065	369	39	the	the	DET
admet-3065	369	40	degradation	degradation	NOUN
admet-3065	369	41	or	or	CCONJ
admet-3065	369	42	translational	translational	ADJ
admet-3065	369	43	suppression	suppression	NOUN
admet-3065	369	44	of	of	ADP
admet-3065	369	45	target	target	NOUN
admet-3065	369	46	mrnas	mrna	NOUN
admet-3065	369	47	[	[	X
admet-3065	369	48	233	233	NUM
admet-3065	369	49	-	-	SYM
admet-3065	369	50	235	235	NUM
admet-3065	369	51	]	]	PUNCT
admet-3065	369	52	.	.	PUNCT
admet-3065	370	1	admet	admet	PROPN
admet-3065	370	2	&	&	CCONJ
admet-3065	370	3	dmpk	dmpk	PROPN
admet-3065	370	4	00(0	00(0	PROPN
admet-3065	370	5	)	)	PUNCT
admet-3065	370	6	(	(	PUNCT
admet-3065	370	7	2025	2025	NUM
admet-3065	370	8	)	)	PUNCT
admet-3065	370	9	3065	3065	NUM
admet-3065	370	10	liposome	liposome	NOUN
admet-3065	370	11	-	-	PUNCT
admet-3065	370	12	mediated	mediate	VERB
admet-3065	370	13	gene	gene	NOUN
admet-3065	370	14	delivery	delivery	NOUN
admet-3065	370	15	doi	doi	NOUN
admet-3065	370	16	:	:	PUNCT
admet-3065	370	17	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	370	18	17	17	NUM
admet-3065	370	19	microrna	microrna	PROPN
admet-3065	370	20	delivery	delivery	NOUN
admet-3065	370	21	micrornas	microrna	NOUN
admet-3065	370	22	(	(	PUNCT
admet-3065	370	23	mirnas	mirna	NOUN
admet-3065	370	24	)	)	PUNCT
admet-3065	370	25	are	be	AUX
admet-3065	370	26	vital	vital	ADJ
admet-3065	370	27	members	member	NOUN
admet-3065	370	28	of	of	ADP
admet-3065	370	29	the	the	DET
admet-3065	370	30	non	non	ADJ
admet-3065	370	31	-	-	ADJ
admet-3065	370	32	coding	coding	ADJ
admet-3065	370	33	rna	rna	NOUN
admet-3065	370	34	(	(	PUNCT
admet-3065	370	35	ncrna	ncrna	NOUN
admet-3065	370	36	)	)	PUNCT
admet-3065	370	37	family	family	NOUN
admet-3065	370	38	,	,	PUNCT
admet-3065	370	39	typically	typically	ADV
admet-3065	370	40	18	18	NUM
admet-3065	370	41	to	to	PART
admet-3065	370	42	24	24	NUM
admet-3065	370	43	nucleotides	nucleotide	NOUN
admet-3065	370	44	in	in	ADP
admet-3065	370	45	length	length	NOUN
admet-3065	370	46	,	,	PUNCT
admet-3065	370	47	that	that	PRON
admet-3065	370	48	regulate	regulate	VERB
admet-3065	370	49	gene	gene	NOUN
admet-3065	370	50	expression	expression	NOUN
admet-3065	370	51	post	post	NOUN
admet-3065	370	52	-	-	ADJ
admet-3065	370	53	transcriptionally	transcriptionally	ADV
admet-3065	370	54	[	[	X
admet-3065	370	55	236	236	NUM
admet-3065	370	56	]	]	PUNCT
admet-3065	370	57	.	.	PUNCT
admet-3065	371	1	mirnas	mirna	NOUN
admet-3065	371	2	are	be	AUX
admet-3065	371	3	involved	involve	VERB
admet-3065	371	4	in	in	ADP
admet-3065	371	5	the	the	DET
admet-3065	371	6	regulation	regulation	NOUN
admet-3065	371	7	of	of	ADP
admet-3065	371	8	critical	critical	ADJ
admet-3065	371	9	cell	cell	NOUN
admet-3065	371	10	processes	process	NOUN
admet-3065	371	11	,	,	PUNCT
admet-3065	371	12	including	include	VERB
admet-3065	371	13	apoptosis	apoptosis	NOUN
admet-3065	371	14	,	,	PUNCT
admet-3065	371	15	cell	cell	NOUN
admet-3065	371	16	growth	growth	NOUN
admet-3065	371	17	,	,	PUNCT
admet-3065	371	18	and	and	CCONJ
admet-3065	371	19	metastasis	metastasis	NOUN
admet-3065	371	20	[	[	X
admet-3065	371	21	236	236	NUM
admet-3065	371	22	-	-	SYM
admet-3065	371	23	238	238	NUM
admet-3065	371	24	]	]	PUNCT
admet-3065	371	25	.	.	PUNCT
admet-3065	372	1	aberrant	aberrant	ADJ
admet-3065	372	2	mirna	mirna	PROPN
admet-3065	372	3	expression	expression	NOUN
admet-3065	372	4	is	be	AUX
admet-3065	372	5	responsible	responsible	ADJ
admet-3065	372	6	for	for	ADP
admet-3065	372	7	a	a	DET
admet-3065	372	8	variety	variety	NOUN
admet-3065	372	9	of	of	ADP
admet-3065	372	10	diseases	disease	NOUN
admet-3065	372	11	,	,	PUNCT
admet-3065	372	12	notably	notably	ADV
admet-3065	372	13	cancer	cancer	NOUN
admet-3065	372	14	,	,	PUNCT
admet-3065	372	15	and	and	CCONJ
admet-3065	372	16	modulation	modulation	NOUN
admet-3065	372	17	of	of	ADP
admet-3065	372	18	mirna	mirna	NOUN
admet-3065	372	19	activity	activity	NOUN
admet-3065	372	20	holds	hold	VERB
admet-3065	372	21	promise	promise	NOUN
admet-3065	372	22	as	as	ADP
admet-3065	372	23	a	a	DET
admet-3065	372	24	future	future	ADJ
admet-3065	372	25	therapeutic	therapeutic	ADJ
admet-3065	372	26	method	method	NOUN
admet-3065	373	1	[	[	X
admet-3065	373	2	239,240	239,240	NUM
admet-3065	373	3	]	]	X
admet-3065	373	4	enhancing	enhance	VERB
admet-3065	373	5	delivery	delivery	NOUN
admet-3065	373	6	with	with	ADP
admet-3065	373	7	physical	physical	ADJ
admet-3065	373	8	methods	method	NOUN
admet-3065	373	9	physical	physical	ADJ
admet-3065	373	10	methods	method	NOUN
admet-3065	373	11	are	be	AUX
admet-3065	373	12	associated	associate	VERB
admet-3065	373	13	with	with	ADP
admet-3065	373	14	employing	employ	VERB
admet-3065	373	15	physical	physical	ADJ
admet-3065	373	16	strength	strength	NOUN
admet-3065	373	17	to	to	PART
admet-3065	373	18	enhance	enhance	VERB
admet-3065	373	19	the	the	DET
admet-3065	373	20	penetrability	penetrability	NOUN
admet-3065	373	21	of	of	ADP
admet-3065	373	22	the	the	DET
admet-3065	373	23	cell	cell	NOUN
admet-3065	373	24	membrane	membrane	NOUN
admet-3065	373	25	,	,	PUNCT
admet-3065	373	26	which	which	PRON
admet-3065	373	27	aids	aid	VERB
admet-3065	373	28	in	in	ADP
admet-3065	373	29	the	the	DET
admet-3065	373	30	delivery	delivery	NOUN
admet-3065	373	31	of	of	ADP
admet-3065	373	32	the	the	DET
admet-3065	373	33	desired	desire	VERB
admet-3065	373	34	gene	gene	NOUN
admet-3065	373	35	.	.	PUNCT
admet-3065	374	1	the	the	DET
admet-3065	374	2	elemental	elemental	ADJ
admet-3065	374	3	superiority	superiority	NOUN
admet-3065	374	4	of	of	ADP
admet-3065	374	5	this	this	DET
admet-3065	374	6	method	method	NOUN
admet-3065	374	7	is	be	AUX
admet-3065	374	8	convenience	convenience	NOUN
admet-3065	374	9	and	and	CCONJ
admet-3065	374	10	reliability	reliability	NOUN
admet-3065	374	11	,	,	PUNCT
admet-3065	374	12	but	but	CCONJ
admet-3065	374	13	a	a	DET
admet-3065	374	14	key	key	ADJ
admet-3065	374	15	disadvantage	disadvantage	NOUN
admet-3065	374	16	is	be	AUX
admet-3065	374	17	the	the	DET
admet-3065	374	18	potential	potential	NOUN
admet-3065	374	19	for	for	ADP
admet-3065	374	20	cell	cell	NOUN
admet-3065	374	21	injury	injury	NOUN
admet-3065	374	22	during	during	ADP
admet-3065	374	23	the	the	DET
admet-3065	374	24	process	process	NOUN
admet-3065	374	25	[	[	X
admet-3065	374	26	241	241	NUM
admet-3065	374	27	]	]	PUNCT
admet-3065	374	28	.	.	PUNCT
admet-3065	375	1	generally	generally	ADV
admet-3065	375	2	,	,	PUNCT
admet-3065	375	3	combining	combine	VERB
admet-3065	375	4	liposomes	liposome	NOUN
admet-3065	375	5	and	and	CCONJ
admet-3065	375	6	physical	physical	ADJ
admet-3065	375	7	gene	gene	NOUN
admet-3065	375	8	delivery	delivery	NOUN
admet-3065	375	9	methods	method	NOUN
admet-3065	375	10	is	be	AUX
admet-3065	375	11	highly	highly	ADV
admet-3065	375	12	recommended	recommend	VERB
admet-3065	375	13	[	[	X
admet-3065	375	14	242	242	NUM
admet-3065	375	15	]	]	SYM
admet-3065	375	16	.	.	PUNCT
admet-3065	376	1	ultrasound	ultrasound	PROPN
admet-3065	376	2	(	(	PUNCT
admet-3065	376	3	sonoporation	sonoporation	NOUN
admet-3065	376	4	)	)	PUNCT
admet-3065	376	5	this	this	DET
admet-3065	376	6	technique	technique	NOUN
admet-3065	376	7	utilizes	utilize	VERB
admet-3065	376	8	physically	physically	ADV
admet-3065	376	9	induced	induce	VERB
admet-3065	376	10	ultrasound	ultrasound	NOUN
admet-3065	376	11	forces	force	NOUN
admet-3065	376	12	to	to	PART
admet-3065	376	13	temporarily	temporarily	ADV
admet-3065	376	14	increase	increase	VERB
admet-3065	376	15	cell	cell	NOUN
admet-3065	376	16	membrane	membrane	NOUN
admet-3065	376	17	permeability	permeability	NOUN
admet-3065	376	18	for	for	ADP
admet-3065	376	19	the	the	DET
admet-3065	376	20	delivery	delivery	NOUN
admet-3065	376	21	of	of	ADP
admet-3065	376	22	genetic	genetic	ADJ
admet-3065	376	23	material	material	NOUN
admet-3065	376	24	[	[	X
admet-3065	376	25	243	243	NUM
admet-3065	376	26	]	]	PUNCT
admet-3065	376	27	.	.	PUNCT
admet-3065	377	1	the	the	DET
admet-3065	377	2	primary	primary	ADJ
admet-3065	377	3	mechanisms	mechanism	NOUN
admet-3065	377	4	are	be	AUX
admet-3065	377	5	cavitation	cavitation	NOUN
admet-3065	377	6	(	(	PUNCT
admet-3065	377	7	the	the	DET
admet-3065	377	8	creation	creation	NOUN
admet-3065	377	9	and	and	CCONJ
admet-3065	377	10	collapse	collapse	NOUN
admet-3065	377	11	of	of	ADP
admet-3065	377	12	microbubbles	microbubble	NOUN
admet-3065	377	13	)	)	PUNCT
admet-3065	377	14	,	,	PUNCT
admet-3065	377	15	radiation	radiation	NOUN
admet-3065	377	16	pressure	pressure	NOUN
admet-3065	377	17	,	,	PUNCT
admet-3065	377	18	and	and	CCONJ
admet-3065	377	19	microstreaming	microstreame	VERB
admet-3065	377	20	,	,	PUNCT
admet-3065	377	21	which	which	PRON
admet-3065	377	22	generate	generate	VERB
admet-3065	377	23	transient	transient	ADJ
admet-3065	377	24	pores	pore	NOUN
admet-3065	377	25	in	in	ADP
admet-3065	377	26	the	the	DET
admet-3065	377	27	membrane	membrane	NOUN
admet-3065	377	28	[	[	X
admet-3065	377	29	244	244	NUM
admet-3065	377	30	]	]	PUNCT
admet-3065	377	31	.	.	PUNCT
admet-3065	378	1	sonoporation	sonoporation	NOUN
admet-3065	378	2	is	be	AUX
admet-3065	378	3	non	non	ADJ
admet-3065	378	4	-	-	ADJ
admet-3065	378	5	invasive	invasive	ADJ
admet-3065	378	6	and	and	CCONJ
admet-3065	378	7	safe	safe	ADJ
admet-3065	378	8	,	,	PUNCT
admet-3065	378	9	but	but	CCONJ
admet-3065	378	10	the	the	DET
admet-3065	378	11	technique	technique	NOUN
admet-3065	378	12	has	have	VERB
admet-3065	378	13	low	low	ADJ
admet-3065	378	14	transfection	transfection	NOUN
admet-3065	378	15	efficiency	efficiency	NOUN
admet-3065	378	16	and	and	CCONJ
admet-3065	378	17	is	be	AUX
admet-3065	378	18	often	often	ADV
admet-3065	378	19	supported	support	VERB
admet-3065	378	20	by	by	ADP
admet-3065	378	21	other	other	ADJ
admet-3065	378	22	delivery	delivery	NOUN
admet-3065	378	23	vectors	vector	NOUN
admet-3065	378	24	,	,	PUNCT
admet-3065	378	25	such	such	ADJ
admet-3065	378	26	as	as	ADP
admet-3065	378	27	liposomes	liposome	NOUN
admet-3065	378	28	,	,	PUNCT
admet-3065	378	29	to	to	PART
admet-3065	378	30	improve	improve	VERB
admet-3065	378	31	outcomes	outcome	NOUN
admet-3065	378	32	[	[	X
admet-3065	378	33	245	245	NUM
admet-3065	378	34	]	]	PUNCT
admet-3065	378	35	.	.	PUNCT
admet-3065	379	1	magnetofection	magnetofection	NOUN
admet-3065	379	2	magnetofection	magnetofection	NOUN
admet-3065	379	3	is	be	AUX
admet-3065	379	4	a	a	DET
admet-3065	379	5	method	method	NOUN
admet-3065	379	6	in	in	ADP
admet-3065	379	7	which	which	PRON
admet-3065	379	8	therapeutic	therapeutic	ADJ
admet-3065	379	9	genetic	genetic	ADJ
admet-3065	379	10	material	material	NOUN
admet-3065	379	11	is	be	AUX
admet-3065	379	12	conjugated	conjugate	VERB
admet-3065	379	13	to	to	ADP
admet-3065	379	14	magnetic	magnetic	ADJ
admet-3065	379	15	nanoparticles	nanoparticle	NOUN
admet-3065	379	16	and	and	CCONJ
admet-3065	379	17	delivered	deliver	VERB
admet-3065	379	18	to	to	PART
admet-3065	379	19	target	target	VERB
admet-3065	379	20	cells	cell	NOUN
admet-3065	379	21	using	use	VERB
admet-3065	379	22	an	an	DET
admet-3065	379	23	external	external	ADJ
admet-3065	379	24	magnetic	magnetic	ADJ
admet-3065	379	25	field	field	NOUN
admet-3065	379	26	[	[	X
admet-3065	379	27	246	246	NUM
admet-3065	379	28	]	]	PUNCT
admet-3065	379	29	.	.	PUNCT
admet-3065	380	1	both	both	PRON
admet-3065	380	2	magnetic	magnetic	ADJ
admet-3065	380	3	fields	field	NOUN
admet-3065	380	4	and	and	CCONJ
admet-3065	380	5	magnetic	magnetic	ADJ
admet-3065	380	6	nanoparticles	nanoparticle	NOUN
admet-3065	380	7	play	play	VERB
admet-3065	380	8	pivotal	pivotal	ADJ
admet-3065	380	9	roles	role	NOUN
admet-3065	380	10	in	in	ADP
admet-3065	380	11	this	this	DET
admet-3065	380	12	technique	technique	NOUN
admet-3065	380	13	,	,	PUNCT
admet-3065	380	14	and	and	CCONJ
admet-3065	380	15	these	these	DET
admet-3065	380	16	elements	element	NOUN
admet-3065	380	17	have	have	AUX
admet-3065	380	18	found	find	VERB
admet-3065	380	19	broad	broad	ADJ
admet-3065	380	20	applications	application	NOUN
admet-3065	380	21	across	across	ADP
admet-3065	380	22	various	various	ADJ
admet-3065	380	23	biological	biological	ADJ
admet-3065	380	24	fields	field	NOUN
admet-3065	380	25	[	[	X
admet-3065	380	26	247	247	NUM
admet-3065	380	27	-	-	SYM
admet-3065	380	28	250	250	NUM
admet-3065	380	29	]	]	PUNCT
admet-3065	380	30	.	.	PUNCT
admet-3065	381	1	for	for	ADP
admet-3065	381	2	in	in	ADP
admet-3065	381	3	vitro	vitro	X
admet-3065	381	4	applications	application	NOUN
admet-3065	381	5	,	,	PUNCT
admet-3065	381	6	electromagnets	electromagnet	NOUN
admet-3065	381	7	are	be	AUX
admet-3065	381	8	placed	place	VERB
admet-3065	381	9	beneath	beneath	ADP
admet-3065	381	10	the	the	DET
admet-3065	381	11	cell	cell	NOUN
admet-3065	381	12	culture	culture	NOUN
admet-3065	381	13	plate	plate	NOUN
admet-3065	381	14	to	to	PART
admet-3065	381	15	attract	attract	VERB
admet-3065	381	16	the	the	DET
admet-3065	381	17	gene	gene	NOUN
admet-3065	381	18	-	-	PUNCT
admet-3065	381	19	magnetic	magnetic	ADJ
admet-3065	381	20	nanoparticle	nanoparticle	NOUN
admet-3065	381	21	complexes	complexe	VERB
admet-3065	381	22	to	to	ADP
admet-3065	381	23	the	the	DET
admet-3065	381	24	cells	cell	NOUN
admet-3065	381	25	,	,	PUNCT
admet-3065	381	26	thereby	thereby	ADV
admet-3065	381	27	significantly	significantly	ADV
admet-3065	381	28	enhancing	enhance	VERB
admet-3065	381	29	uptake	uptake	ADJ
admet-3065	381	30	.	.	PUNCT
admet-3065	382	1	this	this	DET
admet-3065	382	2	method	method	NOUN
admet-3065	382	3	is	be	AUX
admet-3065	382	4	particularly	particularly	ADV
admet-3065	382	5	useful	useful	ADJ
admet-3065	382	6	for	for	ADP
admet-3065	382	7	transfecting	transfecte	VERB
admet-3065	382	8	primary	primary	ADJ
admet-3065	382	9	cells	cell	NOUN
admet-3065	382	10	and	and	CCONJ
admet-3065	382	11	other	other	ADJ
admet-3065	382	12	hard	hard	ADJ
admet-3065	382	13	-	-	PUNCT
admet-3065	382	14	to	to	ADP
admet-3065	382	15	-	-	PUNCT
admet-3065	382	16	transfect	transfect	NOUN
admet-3065	382	17	cell	cell	NOUN
admet-3065	382	18	types	type	NOUN
admet-3065	382	19	[	[	X
admet-3065	382	20	251	251	NUM
admet-3065	382	21	]	]	PUNCT
admet-3065	382	22	.	.	PUNCT
admet-3065	383	1	electroporation	electroporation	NOUN
admet-3065	383	2	dna	dna	NOUN
admet-3065	383	3	can	can	AUX
admet-3065	383	4	be	be	AUX
admet-3065	383	5	transfected	transfecte	VERB
admet-3065	383	6	into	into	ADP
admet-3065	383	7	any	any	DET
admet-3065	383	8	cell	cell	NOUN
admet-3065	383	9	by	by	ADP
admet-3065	383	10	applying	apply	VERB
admet-3065	383	11	controlled	control	VERB
admet-3065	383	12	short	short	ADJ
admet-3065	383	13	electrical	electrical	ADJ
admet-3065	383	14	impulses	impulse	NOUN
admet-3065	383	15	[	[	X
admet-3065	383	16	252	252	NUM
admet-3065	383	17	]	]	PUNCT
admet-3065	383	18	.	.	PUNCT
admet-3065	384	1	an	an	DET
admet-3065	384	2	electric	electric	ADJ
admet-3065	384	3	impulse	impulse	NOUN
admet-3065	384	4	is	be	AUX
admet-3065	384	5	sufficient	sufficient	ADJ
admet-3065	384	6	to	to	PART
admet-3065	384	7	transiently	transiently	ADV
admet-3065	384	8	alter	alter	VERB
admet-3065	384	9	the	the	DET
admet-3065	384	10	structure	structure	NOUN
admet-3065	384	11	of	of	ADP
admet-3065	384	12	the	the	DET
admet-3065	384	13	cell	cell	NOUN
admet-3065	384	14	membrane	membrane	NOUN
admet-3065	384	15	,	,	PUNCT
admet-3065	384	16	creating	create	VERB
admet-3065	384	17	pores	pore	NOUN
admet-3065	384	18	that	that	PRON
admet-3065	384	19	enable	enable	VERB
admet-3065	384	20	nanosized	nanosized	ADJ
admet-3065	384	21	oligonucleotides	oligonucleotide	NOUN
admet-3065	384	22	and	and	CCONJ
admet-3065	384	23	chemical	chemical	NOUN
admet-3065	384	24	compounds	compound	NOUN
admet-3065	384	25	to	to	PART
admet-3065	384	26	enter	enter	VERB
admet-3065	384	27	the	the	DET
admet-3065	384	28	cell	cell	NOUN
admet-3065	384	29	[	[	X
admet-3065	384	30	253	253	NUM
admet-3065	384	31	]	]	PUNCT
admet-3065	384	32	.	.	PUNCT
admet-3065	385	1	it	it	PRON
admet-3065	385	2	is	be	AUX
admet-3065	385	3	a	a	DET
admet-3065	385	4	cost	cost	NOUN
admet-3065	385	5	-	-	PUNCT
admet-3065	385	6	effective	effective	ADJ
admet-3065	385	7	,	,	PUNCT
admet-3065	385	8	quick	quick	ADJ
admet-3065	385	9	,	,	PUNCT
admet-3065	385	10	and	and	CCONJ
admet-3065	385	11	highly	highly	ADV
admet-3065	385	12	reliable	reliable	ADJ
admet-3065	385	13	method	method	NOUN
admet-3065	385	14	that	that	PRON
admet-3065	385	15	can	can	AUX
admet-3065	385	16	be	be	AUX
admet-3065	385	17	as	as	ADV
admet-3065	385	18	effective	effective	ADJ
admet-3065	385	19	as	as	ADP
admet-3065	385	20	viral	viral	ADJ
admet-3065	385	21	transfection	transfection	NOUN
admet-3065	385	22	.	.	PUNCT
admet-3065	386	1	however	however	ADV
admet-3065	386	2	,	,	PUNCT
admet-3065	386	3	extensive	extensive	ADJ
admet-3065	386	4	optimization	optimization	NOUN
admet-3065	386	5	of	of	ADP
admet-3065	386	6	conditions	condition	NOUN
admet-3065	386	7	is	be	AUX
admet-3065	386	8	required	require	VERB
admet-3065	386	9	,	,	PUNCT
admet-3065	386	10	as	as	SCONJ
admet-3065	386	11	the	the	DET
admet-3065	386	12	cell	cell	NOUN
admet-3065	386	13	death	death	NOUN
admet-3065	386	14	rate	rate	NOUN
admet-3065	386	15	in	in	ADP
admet-3065	386	16	cells	cell	NOUN
admet-3065	386	17	subjected	subject	VERB
admet-3065	386	18	to	to	ADP
admet-3065	386	19	this	this	DET
admet-3065	386	20	method	method	NOUN
admet-3065	386	21	is	be	AUX
admet-3065	386	22	high	high	ADJ
admet-3065	387	1	[	[	X
admet-3065	387	2	254	254	NUM
admet-3065	387	3	]	]	PUNCT
admet-3065	387	4	.	.	PUNCT
admet-3065	388	1	laser	laser	NOUN
admet-3065	388	2	(	(	PUNCT
admet-3065	388	3	optoporation	optoporation	NOUN
admet-3065	388	4	)	)	PUNCT
admet-3065	388	5	light	light	ADJ
admet-3065	388	6	amplification	amplification	NOUN
admet-3065	388	7	by	by	ADP
admet-3065	388	8	stimulated	stimulated	ADJ
admet-3065	388	9	emission	emission	NOUN
admet-3065	388	10	of	of	ADP
admet-3065	388	11	radiation	radiation	NOUN
admet-3065	388	12	(	(	PUNCT
admet-3065	388	13	laser	laser	NOUN
admet-3065	388	14	)	)	PUNCT
admet-3065	388	15	assisted	assist	VERB
admet-3065	388	16	transfection	transfection	NOUN
admet-3065	388	17	,	,	PUNCT
admet-3065	388	18	also	also	ADV
admet-3065	388	19	called	call	VERB
admet-3065	388	20	photo	photo	NOUN
admet-3065	388	21	transfection	transfection	NOUN
admet-3065	388	22	or	or	CCONJ
admet-3065	388	23	optoporation	optoporation	NOUN
admet-3065	388	24	,	,	PUNCT
admet-3065	388	25	relies	rely	VERB
admet-3065	388	26	on	on	ADP
admet-3065	388	27	the	the	DET
admet-3065	388	28	concept	concept	NOUN
admet-3065	388	29	that	that	SCONJ
admet-3065	388	30	a	a	DET
admet-3065	388	31	laser	laser	NOUN
admet-3065	388	32	pulse	pulse	NOUN
admet-3065	388	33	can	can	AUX
admet-3065	388	34	transiently	transiently	ADV
admet-3065	388	35	modulate	modulate	VERB
admet-3065	388	36	cell	cell	NOUN
admet-3065	388	37	membrane	membrane	NOUN
admet-3065	388	38	permeability	permeability	NOUN
admet-3065	388	39	[	[	X
admet-3065	388	40	255,256	255,256	NUM
admet-3065	388	41	]	]	PUNCT
admet-3065	388	42	.	.	PUNCT
admet-3065	389	1	the	the	DET
admet-3065	389	2	subsequent	subsequent	ADJ
admet-3065	389	3	pore	pore	ADJ
admet-3065	389	4	formation	formation	NOUN
admet-3065	389	5	leads	lead	VERB
admet-3065	389	6	to	to	ADP
admet-3065	389	7	an	an	DET
admet-3065	389	8	osmotic	osmotic	ADJ
admet-3065	389	9	difference	difference	NOUN
admet-3065	389	10	between	between	ADP
admet-3065	389	11	the	the	DET
admet-3065	389	12	cytosol	cytosol	NOUN
admet-3065	389	13	and	and	CCONJ
admet-3065	389	14	the	the	DET
admet-3065	389	15	medium	medium	NOUN
admet-3065	389	16	,	,	PUNCT
admet-3065	389	17	thereby	thereby	ADV
admet-3065	389	18	facilitating	facilitate	VERB
admet-3065	389	19	the	the	DET
admet-3065	389	20	entry	entry	NOUN
admet-3065	389	21	of	of	ADP
admet-3065	389	22	genetic	genetic	ADJ
admet-3065	389	23	materials	material	NOUN
admet-3065	389	24	into	into	ADP
admet-3065	389	25	the	the	DET
admet-3065	389	26	desired	desire	VERB
admet-3065	389	27	cell	cell	NOUN
admet-3065	390	1	[	[	X
admet-3065	390	2	42	42	NUM
admet-3065	390	3	]	]	PUNCT
admet-3065	390	4	.	.	PUNCT
admet-3065	391	1	conclusions	conclusion	NOUN
admet-3065	391	2	liposomes	liposome	NOUN
admet-3065	391	3	stand	stand	VERB
admet-3065	391	4	as	as	ADP
admet-3065	391	5	a	a	DET
admet-3065	391	6	versatile	versatile	ADJ
admet-3065	391	7	and	and	CCONJ
admet-3065	391	8	powerful	powerful	ADJ
admet-3065	391	9	platform	platform	NOUN
admet-3065	391	10	technology	technology	NOUN
admet-3065	391	11	for	for	ADP
admet-3065	391	12	dna	dna	PROPN
admet-3065	391	13	,	,	PUNCT
admet-3065	391	14	mrna	mrna	PROPN
admet-3065	391	15	,	,	PUNCT
admet-3065	391	16	and	and	CCONJ
admet-3065	391	17	sirna	sirna	PROPN
admet-3065	391	18	delivery	delivery	NOUN
admet-3065	391	19	in	in	ADP
admet-3065	391	20	the	the	DET
admet-3065	391	21	rapidly	rapidly	ADV
admet-3065	391	22	advancing	advance	VERB
admet-3065	391	23	field	field	NOUN
admet-3065	391	24	of	of	ADP
admet-3065	391	25	gene	gene	NOUN
admet-3065	391	26	therapy	therapy	NOUN
admet-3065	391	27	.	.	PUNCT
admet-3065	392	1	their	their	PRON
admet-3065	392	2	remarkable	remarkable	ADJ
admet-3065	392	3	tunability	tunability	NOUN
admet-3065	392	4	in	in	ADP
admet-3065	392	5	terms	term	NOUN
admet-3065	392	6	of	of	ADP
admet-3065	392	7	composition	composition	NOUN
admet-3065	392	8	,	,	PUNCT
admet-3065	392	9	size	size	NOUN
admet-3065	392	10	,	,	PUNCT
admet-3065	392	11	charge	charge	NOUN
admet-3065	392	12	,	,	PUNCT
admet-3065	392	13	and	and	CCONJ
admet-3065	392	14	surface	surface	NOUN
admet-3065	392	15	modification	modification	NOUN
admet-3065	392	16	allows	allow	VERB
admet-3065	392	17	for	for	ADP
admet-3065	392	18	the	the	DET
admet-3065	392	19	rational	rational	ADJ
admet-3065	392	20	design	design	NOUN
admet-3065	392	21	of	of	ADP
admet-3065	392	22	vectors	vector	NOUN
admet-3065	392	23	tailored	tailor	VERB
admet-3065	392	24	to	to	ADP
admet-3065	392	25	specific	specific	ADJ
admet-3065	392	26	therapeutic	therapeutic	ADJ
admet-3065	392	27	needs	need	NOUN
admet-3065	392	28	.	.	PUNCT
admet-3065	393	1	the	the	DET
admet-3065	393	2	ongoing	ongoing	ADJ
admet-3065	393	3	exploration	exploration	NOUN
admet-3065	393	4	of	of	ADP
admet-3065	393	5	novel	novel	ADJ
admet-3065	393	6	lipid	lipid	NOUN
admet-3065	393	7	structures	structure	NOUN
admet-3065	393	8	,	,	PUNCT
admet-3065	393	9	particularly	particularly	ADV
admet-3065	393	10	those	those	PRON
admet-3065	393	11	with	with	ADP
admet-3065	393	12	biodegradable	biodegradable	ADJ
admet-3065	393	13	linkers	linker	NOUN
admet-3065	393	14	and	and	CCONJ
admet-3065	393	15	ph	ph	VERB
admet-3065	393	16	-	-	PUNCT
admet-3065	393	17	responsive	responsive	ADJ
admet-3065	393	18	headgroups	headgroup	NOUN
admet-3065	393	19	,	,	PUNCT
admet-3065	393	20	e.	e.	PROPN
admet-3065	393	21	j.	j.	PROPN
admet-3065	393	22	saleh	saleh	PROPN
admet-3065	393	23	et	et	PROPN
admet-3065	393	24	al	al	PROPN
admet-3065	393	25	.	.	PROPN
admet-3065	393	26	admet	admet	PROPN
admet-3065	393	27	&	&	CCONJ
admet-3065	393	28	dmpk	dmpk	PROPN
admet-3065	393	29	00(0	00(0	PROPN
admet-3065	393	30	)	)	PUNCT
admet-3065	393	31	(	(	PUNCT
admet-3065	393	32	2025	2025	NUM
admet-3065	393	33	)	)	PUNCT
admet-3065	393	34	3065	3065	NUM
admet-3065	393	35	18	18	NUM
admet-3065	393	36	continues	continue	VERB
admet-3065	393	37	to	to	PART
admet-3065	393	38	push	push	VERB
admet-3065	393	39	the	the	DET
admet-3065	393	40	boundaries	boundary	NOUN
admet-3065	393	41	of	of	ADP
admet-3065	393	42	transfection	transfection	NOUN
admet-3065	393	43	efficiency	efficiency	NOUN
admet-3065	393	44	while	while	SCONJ
admet-3065	393	45	minimizing	minimize	VERB
admet-3065	393	46	cytotoxicity	cytotoxicity	NOUN
admet-3065	393	47	.	.	PUNCT
admet-3065	394	1	furthermore	furthermore	ADV
admet-3065	394	2	,	,	PUNCT
admet-3065	394	3	the	the	DET
admet-3065	394	4	integration	integration	NOUN
admet-3065	394	5	of	of	ADP
admet-3065	394	6	active	active	ADJ
admet-3065	394	7	targeting	targeting	NOUN
admet-3065	394	8	moieties	moiety	NOUN
admet-3065	394	9	and	and	CCONJ
admet-3065	394	10	stimuli	stimulus	NOUN
admet-3065	394	11	-	-	PUNCT
admet-3065	394	12	responsive	responsive	ADJ
admet-3065	394	13	components	component	NOUN
admet-3065	394	14	is	be	AUX
admet-3065	394	15	paving	pave	VERB
admet-3065	394	16	the	the	DET
admet-3065	394	17	way	way	NOUN
admet-3065	394	18	for	for	ADP
admet-3065	394	19	highly	highly	ADV
admet-3065	394	20	specific	specific	ADJ
admet-3065	394	21	,	,	PUNCT
admet-3065	394	22	"	"	PUNCT
admet-3065	394	23	smart	smart	ADJ
admet-3065	394	24	"	"	PUNCT
admet-3065	394	25	delivery	delivery	NOUN
admet-3065	394	26	systems	system	NOUN
admet-3065	394	27	capable	capable	ADJ
admet-3065	394	28	of	of	ADP
admet-3065	394	29	navigating	navigate	VERB
admet-3065	394	30	complex	complex	ADJ
admet-3065	394	31	biological	biological	ADJ
admet-3065	394	32	barriers	barrier	NOUN
admet-3065	394	33	.	.	PUNCT
admet-3065	395	1	while	while	SCONJ
admet-3065	395	2	challenges	challenge	NOUN
admet-3065	395	3	related	relate	VERB
admet-3065	395	4	to	to	ADP
admet-3065	395	5	in	in	ADP
admet-3065	395	6	vivo	vivo	ADJ
admet-3065	395	7	stability	stability	NOUN
admet-3065	395	8	,	,	PUNCT
admet-3065	395	9	endosomal	endosomal	ADJ
admet-3065	395	10	escape	escape	NOUN
admet-3065	395	11	,	,	PUNCT
admet-3065	395	12	and	and	CCONJ
admet-3065	395	13	large	large	ADJ
admet-3065	395	14	-	-	PUNCT
admet-3065	395	15	scale	scale	NOUN
admet-3065	395	16	manufacturing	manufacturing	NOUN
admet-3065	395	17	persist	persist	NOUN
admet-3065	395	18	,	,	PUNCT
admet-3065	395	19	the	the	DET
admet-3065	395	20	synergistic	synergistic	ADJ
admet-3065	395	21	combination	combination	NOUN
admet-3065	395	22	of	of	ADP
admet-3065	395	23	advanced	advanced	ADJ
admet-3065	395	24	liposomal	liposomal	ADJ
admet-3065	395	25	formulations	formulation	NOUN
admet-3065	395	26	with	with	ADP
admet-3065	395	27	physical	physical	ADJ
admet-3065	395	28	enhancement	enhancement	NOUN
admet-3065	395	29	techniques	technique	NOUN
admet-3065	395	30	holds	hold	VERB
admet-3065	395	31	immense	immense	ADJ
admet-3065	395	32	promise	promise	NOUN
admet-3065	395	33	.	.	PUNCT
admet-3065	396	1	as	as	SCONJ
admet-3065	396	2	our	our	PRON
admet-3065	396	3	understanding	understanding	NOUN
admet-3065	396	4	of	of	ADP
admet-3065	396	5	the	the	DET
admet-3065	396	6	intricate	intricate	ADJ
admet-3065	396	7	interactions	interaction	NOUN
admet-3065	396	8	between	between	ADP
admet-3065	396	9	nanocarriers	nanocarrier	NOUN
admet-3065	396	10	and	and	CCONJ
admet-3065	396	11	biological	biological	ADJ
admet-3065	396	12	systems	system	NOUN
admet-3065	396	13	deepens	deepen	NOUN
admet-3065	396	14	,	,	PUNCT
admet-3065	396	15	liposome	liposome	NOUN
admet-3065	396	16	-	-	PUNCT
admet-3065	396	17	based	base	VERB
admet-3065	396	18	vectors	vector	NOUN
admet-3065	396	19	are	be	AUX
admet-3065	396	20	poised	poise	VERB
admet-3065	396	21	to	to	PART
admet-3065	396	22	play	play	VERB
admet-3065	396	23	an	an	DET
admet-3065	396	24	indispensable	indispensable	ADJ
admet-3065	396	25	role	role	NOUN
admet-3065	396	26	in	in	ADP
admet-3065	396	27	translating	translate	VERB
admet-3065	396	28	the	the	DET
admet-3065	396	29	potential	potential	NOUN
admet-3065	396	30	of	of	ADP
admet-3065	396	31	gene	gene	NOUN
admet-3065	396	32	therapy	therapy	NOUN
admet-3065	396	33	into	into	ADP
admet-3065	396	34	tangible	tangible	ADJ
admet-3065	396	35	clinical	clinical	ADJ
admet-3065	396	36	realities	reality	NOUN
admet-3065	396	37	.	.	PUNCT
admet-3065	397	1	abbreviations	abbreviation	NOUN
admet-3065	397	2	abc	abc	PROPN
admet-3065	397	3	accelerated	accelerate	VERB
admet-3065	397	4	blood	blood	NOUN
admet-3065	397	5	clearance	clearance	NOUN
admet-3065	397	6	ac	ac	PROPN
admet-3065	397	7	-	-	PUNCT
admet-3065	397	8	chol	chol	ADJ
admet-3065	397	9	amino	amino	PROPN
admet-3065	397	10	cholesterol	cholesterol	PROPN
admet-3065	397	11	bbb	bbb	PROPN
admet-3065	397	12	blood	blood	NOUN
admet-3065	397	13	-	-	PUNCT
admet-3065	397	14	brain	brain	NOUN
admet-3065	397	15	barrier	barrier	NOUN
admet-3065	397	16	bgtc	bgtc	NOUN
admet-3065	397	17	bis(guanidinium)-tren	bis(guanidinium)-tren	PROPN
admet-3065	397	18	cholesterol	cholesterol	PROPN
admet-3065	397	19	crispr	crispr	NOUN
admet-3065	397	20	clustered	cluster	VERB
admet-3065	397	21	regularly	regularly	ADV
admet-3065	397	22	interspaced	interspace	VERB
admet-3065	397	23	short	short	ADJ
admet-3065	397	24	palindromic	palindromic	ADJ
admet-3065	397	25	repeats	repeat	NOUN
admet-3065	397	26	dc	dc	PROPN
admet-3065	397	27	-	-	PUNCT
admet-3065	397	28	chol	chol	NOUN
admet-3065	397	29	3β-[n-(n′,n′-dimethylaminoethane)-carbamoyl]cholesterol	3β-[n-(n′,n′-dimethylaminoethane)-carbamoyl]cholesterol	PROPN
admet-3065	397	30	deae	deae	PROPN
admet-3065	397	31	diethylaminoethyl	diethylaminoethyl	PROPN
admet-3065	397	32	dogs	dog	VERB
admet-3065	397	33	di	di	NOUN
admet-3065	397	34	-	-	ADJ
admet-3065	397	35	octadecyl	octadecyl	NOUN
admet-3065	397	36	-	-	PUNCT
admet-3065	397	37	amido	amido	NOUN
admet-3065	397	38	-	-	PUNCT
admet-3065	397	39	glycyl	glycyl	NOUN
admet-3065	397	40	-	-	PUNCT
admet-3065	397	41	spermine	spermine	NOUN
admet-3065	397	42	dogsdso	dogsdso	PROPN
admet-3065	397	43	di	di	NOUN
admet-3065	397	44	-	-	PUNCT
admet-3065	397	45	octadecyl	octadecyl	NOUN
admet-3065	397	46	-	-	PUNCT
admet-3065	397	47	amido	amido	NOUN
admet-3065	397	48	-	-	PUNCT
admet-3065	397	49	glycyl	glycyl	NOUN
admet-3065	397	50	-	-	PUNCT
admet-3065	397	51	spermine	spermine	NOUN
admet-3065	397	52	disulfide	disulfide	NOUN
admet-3065	397	53	oxide	oxide	NOUN
admet-3065	397	54	dopc	dopc	NOUN
admet-3065	397	55	1,2	1,2	NUM
admet-3065	397	56	-	-	PUNCT
admet-3065	397	57	dioleoyl	dioleoyl	ADJ
admet-3065	397	58	-	-	PUNCT
admet-3065	397	59	sn	sn	NOUN
admet-3065	397	60	-	-	PUNCT
admet-3065	397	61	glycero-3	glycero-3	NOUN
admet-3065	397	62	-	-	PUNCT
admet-3065	397	63	phosphocholine	phosphocholine	NOUN
admet-3065	397	64	dope	dope	NOUN
admet-3065	397	65	1,2	1,2	NUM
admet-3065	397	66	-	-	PUNCT
admet-3065	397	67	dioleoyl	dioleoyl	ADJ
admet-3065	397	68	-	-	PUNCT
admet-3065	397	69	sn	sn	NOUN
admet-3065	397	70	-	-	PUNCT
admet-3065	397	71	glycero-3	glycero-3	NOUN
admet-3065	397	72	-	-	PUNCT
admet-3065	397	73	phosphoethanolamine	phosphoethanolamine	NOUN
admet-3065	397	74	dospa	dospa	NOUN
admet-3065	397	75	2,3	2,3	NUM
admet-3065	397	76	-	-	PUNCT
admet-3065	397	77	dioleyloxy	dioleyloxy	NOUN
admet-3065	397	78	-	-	PUNCT
admet-3065	397	79	n-[2(sperminecarboxamido)ethyl]-n	n-[2(sperminecarboxamido)ethyl]-n	NOUN
admet-3065	397	80	,	,	PUNCT
admet-3065	397	81	n	n	CCONJ
admet-3065	397	82	-	-	PUNCT
admet-3065	397	83	dimethyl	dimethyl	NOUN
admet-3065	397	84	-	-	PUNCT
admet-3065	397	85	l	l	NOUN
admet-3065	397	86	-	-	ADJ
admet-3065	397	87	propanaminium	propanaminium	NOUN
admet-3065	397	88	trifluoroacetate	trifluoroacetate	NOUN
admet-3065	397	89	dotap	dotap	NOUN
admet-3065	397	90	1,2	1,2	NUM
admet-3065	397	91	-	-	PUNCT
admet-3065	397	92	bis(oleoyloxy)-3-(trimethylammonio)propane	bis(oleoyloxy)-3-(trimethylammonio)propane	NOUN
admet-3065	397	93	dotma	dotma	ADJ
admet-3065	397	94	n-[1-(2,3	n-[1-(2,3	NOUN
admet-3065	397	95	-	-	PUNCT
admet-3065	397	96	dioleyloxy)propyl]-n	dioleyloxy)propyl]-n	NOUN
admet-3065	397	97	,	,	PUNCT
admet-3065	397	98	n	n	CCONJ
admet-3065	397	99	,	,	PUNCT
admet-3065	397	100	n	n	CCONJ
admet-3065	397	101	-	-	PUNCT
admet-3065	397	102	trimethylammonium	trimethylammonium	NOUN
admet-3065	397	103	chloride	chloride	PROPN
admet-3065	397	104	dppc	dppc	PROPN
admet-3065	397	105	1,2	1,2	NUM
admet-3065	397	106	-	-	PUNCT
admet-3065	397	107	dipalmitoyl	dipalmitoyl	ADJ
admet-3065	397	108	-	-	PUNCT
admet-3065	397	109	sn	sn	NOUN
admet-3065	397	110	-	-	PUNCT
admet-3065	397	111	glycero-3	glycero-3	NOUN
admet-3065	397	112	-	-	PUNCT
admet-3065	397	113	phosphocholine	phosphocholine	NOUN
admet-3065	397	114	dspc	dspc	NOUN
admet-3065	397	115	1,2	1,2	NUM
admet-3065	397	116	-	-	PUNCT
admet-3065	397	117	distearoyl	distearoyl	NOUN
admet-3065	397	118	-	-	PUNCT
admet-3065	397	119	sn	sn	NOUN
admet-3065	397	120	-	-	PUNCT
admet-3065	397	121	glycero-3	glycero-3	NOUN
admet-3065	397	122	-	-	PUNCT
admet-3065	397	123	phosphocholine	phosphocholine	NOUN
admet-3065	397	124	epr	epr	PROPN
admet-3065	397	125	enhanced	enhance	VERB
admet-3065	397	126	permeability	permeability	NOUN
admet-3065	397	127	and	and	CCONJ
admet-3065	397	128	retention	retention	NOUN
admet-3065	397	129	ecm	ecm	NOUN
admet-3065	397	130	extracellular	extracellular	ADJ
admet-3065	397	131	matrix	matrix	NOUN
admet-3065	397	132	guv	guv	NOUN
admet-3065	397	133	giant	giant	ADJ
admet-3065	397	134	unilamellar	unilamellar	ADJ
admet-3065	397	135	vesicle	vesicle	NOUN
admet-3065	397	136	hspc	hspc	NOUN
admet-3065	397	137	hydrogenated	hydrogenate	VERB
admet-3065	397	138	soy	soy	NOUN
admet-3065	397	139	phosphatidylcholine	phosphatidylcholine	NOUN
admet-3065	397	140	laser	laser	NOUN
admet-3065	397	141	light	light	ADJ
admet-3065	397	142	amplification	amplification	NOUN
admet-3065	397	143	by	by	ADP
admet-3065	397	144	stimulated	stimulated	ADJ
admet-3065	397	145	emission	emission	NOUN
admet-3065	397	146	of	of	ADP
admet-3065	397	147	radiation	radiation	NOUN
admet-3065	397	148	ld	ld	NOUN
admet-3065	397	149	liquid	liquid	NOUN
admet-3065	397	150	-	-	PUNCT
admet-3065	397	151	disordered	disorder	VERB
admet-3065	397	152	phase	phase	NOUN
admet-3065	397	153	lo	lo	PROPN
admet-3065	397	154	liquid	liquid	NOUN
admet-3065	397	155	-	-	PUNCT
admet-3065	397	156	ordered	order	VERB
admet-3065	397	157	phase	phase	NOUN
admet-3065	397	158	luv	luv	PROPN
admet-3065	397	159	large	large	ADJ
admet-3065	397	160	unilamellar	unilamellar	ADJ
admet-3065	397	161	vesicle	vesicle	NOUN
admet-3065	397	162	mflp	mflp	PRON
admet-3065	397	163	membrane	membrane	NOUN
admet-3065	397	164	-	-	PUNCT
admet-3065	397	165	fusogenic	fusogenic	ADJ
admet-3065	397	166	liposome	liposome	NOUN
admet-3065	397	167	mlv	mlv	VERB
admet-3065	397	168	multilamellar	multilamellar	ADJ
admet-3065	397	169	vesicle	vesicle	NOUN
admet-3065	397	170	mps	mp	NOUN
admet-3065	397	171	mononuclear	mononuclear	VERB
admet-3065	397	172	phagocytic	phagocytic	ADJ
admet-3065	397	173	system	system	NOUN
admet-3065	397	174	np	np	INTJ
admet-3065	397	175	nanoparticle	nanoparticle	VERB
admet-3065	397	176	olv	olv	PROPN
admet-3065	397	177	oligolamellar	oligolamellar	ADJ
admet-3065	397	178	vesicle	vesicle	NOUN
admet-3065	397	179	pa	pa	PROPN
admet-3065	397	180	phosphatidic	phosphatidic	ADJ
admet-3065	397	181	acid	acid	NOUN
admet-3065	397	182	pc	pc	NOUN
admet-3065	397	183	phosphatidylcholine	phosphatidylcholine	NOUN
admet-3065	398	1	pe	pe	PROPN
admet-3065	398	2	phosphatidylethanolamine	phosphatidylethanolamine	PROPN
admet-3065	398	3	peg	peg	NOUN
admet-3065	398	4	polyethylene	polyethylene	NOUN
admet-3065	398	5	glycol	glycol	NOUN
admet-3065	398	6	peg	peg	NOUN
admet-3065	398	7	-	-	PUNCT
admet-3065	398	8	dspe	dspe	NOUN
admet-3065	398	9	polyethylene	polyethylene	NOUN
admet-3065	398	10	glycol	glycol	NOUN
admet-3065	398	11	-	-	PUNCT
admet-3065	398	12	distearoylphosphatidylethanolamine	distearoylphosphatidylethanolamine	NOUN
admet-3065	398	13	pdna	pdna	PROPN
admet-3065	398	14	plasmid	plasmid	PROPN
admet-3065	398	15	dna	dna	PROPN
admet-3065	398	16	sirna	sirna	PROPN
admet-3065	398	17	small	small	ADJ
admet-3065	398	18	interfering	interfere	VERB
admet-3065	398	19	rna	rna	NOUN
admet-3065	398	20	tc	tc	NOUN
admet-3065	398	21	phase	phase	NOUN
admet-3065	398	22	transition	transition	NOUN
admet-3065	398	23	temperature	temperature	NOUN
admet-3065	398	24	tem	tem	PROPN
admet-3065	398	25	transmission	transmission	NOUN
admet-3065	398	26	electron	electron	NOUN
admet-3065	398	27	microscopy	microscopy	NOUN
admet-3065	398	28	funding	funding	NOUN
admet-3065	398	29	:	:	PUNCT
admet-3065	398	30	not	not	PART
admet-3065	398	31	applicable	applicable	ADJ
admet-3065	398	32	.	.	PUNCT
admet-3065	399	1	conflict	conflict	NOUN
admet-3065	399	2	of	of	ADP
admet-3065	399	3	interest	interest	NOUN
admet-3065	399	4	:	:	PUNCT
admet-3065	399	5	the	the	DET
admet-3065	399	6	authors	author	NOUN
admet-3065	399	7	certify	certify	VERB
admet-3065	399	8	that	that	SCONJ
admet-3065	399	9	they	they	PRON
admet-3065	399	10	have	have	VERB
admet-3065	399	11	no	no	DET
admet-3065	399	12	financial	financial	ADJ
admet-3065	399	13	or	or	CCONJ
admet-3065	399	14	other	other	ADJ
admet-3065	399	15	conflicts	conflict	NOUN
admet-3065	399	16	of	of	ADP
admet-3065	399	17	interest	interest	NOUN
admet-3065	399	18	.	.	PUNCT
admet-3065	400	1	references	reference	NOUN
admet-3065	400	2	[	[	X
admet-3065	400	3	1	1	NUM
admet-3065	400	4	]	]	PUNCT
admet-3065	400	5	f.	f.	PROPN
admet-3065	400	6	arabi	arabi	PROPN
admet-3065	400	7	,	,	PUNCT
admet-3065	400	8	v.	v.	PROPN
admet-3065	400	9	mansouri	mansouri	PROPN
admet-3065	400	10	,	,	PUNCT
admet-3065	400	11	n.	n.	NOUN
admet-3065	400	12	ahmadbeigi	ahmadbeigi	PROPN
admet-3065	400	13	.	.	PUNCT
admet-3065	401	1	gene	gene	NOUN
admet-3065	401	2	therapy	therapy	NOUN
admet-3065	401	3	clinical	clinical	ADJ
admet-3065	401	4	trials	trial	NOUN
admet-3065	401	5	,	,	PUNCT
admet-3065	401	6	where	where	SCONJ
admet-3065	401	7	do	do	AUX
admet-3065	401	8	we	we	PRON
admet-3065	401	9	go	go	VERB
admet-3065	401	10	?	?	PUNCT
admet-3065	402	1	an	an	DET
admet-3065	402	2	overview	overview	NOUN
admet-3065	402	3	.	.	PUNCT
admet-3065	403	1	biomedicine	biomedicine	NOUN
admet-3065	403	2	and	and	CCONJ
admet-3065	403	3	pharmacotherapy	pharmacotherapy	NOUN
admet-3065	403	4	153	153	NUM
admet-3065	403	5	(	(	PUNCT
admet-3065	403	6	2022	2022	NUM
admet-3065	403	7	)	)	PUNCT
admet-3065	403	8	113324	113324	NUM
admet-3065	403	9	.	.	PUNCT
admet-3065	404	1	https://doi.org/10.1016/j.biopha.2022.113324	https://doi.org/10.1016/j.biopha.2022.113324	PROPN
admet-3065	404	2	https://doi.org/10.1016/j.biopha.2022.113324	https://doi.org/10.1016/j.biopha.2022.113324	PROPN
admet-3065	404	3	.	.	PUNCT
admet-3065	405	1	admet	admet	PROPN
admet-3065	405	2	&	&	CCONJ
admet-3065	405	3	dmpk	dmpk	PROPN
admet-3065	405	4	00(0	00(0	PROPN
admet-3065	405	5	)	)	PUNCT
admet-3065	405	6	(	(	PUNCT
admet-3065	405	7	2025	2025	NUM
admet-3065	405	8	)	)	PUNCT
admet-3065	405	9	3065	3065	NUM
admet-3065	405	10	liposome	liposome	NOUN
admet-3065	405	11	-	-	PUNCT
admet-3065	405	12	mediated	mediate	VERB
admet-3065	405	13	gene	gene	NOUN
admet-3065	405	14	delivery	delivery	NOUN
admet-3065	405	15	doi	doi	NOUN
admet-3065	405	16	:	:	PUNCT
admet-3065	405	17	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	405	18	19	19	NUM
admet-3065	406	1	[	[	X
admet-3065	406	2	2	2	NUM
admet-3065	406	3	]	]	PUNCT
admet-3065	406	4	h.	h.	PROPN
admet-3065	406	5	maeda	maeda	PROPN
admet-3065	406	6	,	,	PUNCT
admet-3065	406	7	j.	j.	PROPN
admet-3065	406	8	wu	wu	PROPN
admet-3065	406	9	,	,	PUNCT
admet-3065	406	10	t.	t.	PROPN
admet-3065	406	11	sawa	sawa	PROPN
admet-3065	406	12	,	,	PUNCT
admet-3065	406	13	y.	y.	PROPN
admet-3065	406	14	matsumura	matsumura	PROPN
admet-3065	406	15	,	,	PUNCT
admet-3065	406	16	k.	k.	PROPN
admet-3065	406	17	hori	hori	PROPN
admet-3065	406	18	.	.	PUNCT
admet-3065	407	1	tumor	tumor	NOUN
admet-3065	407	2	vascular	vascular	ADJ
admet-3065	407	3	permeability	permeability	NOUN
admet-3065	407	4	and	and	CCONJ
admet-3065	407	5	the	the	DET
admet-3065	407	6	epr	epr	PROPN
admet-3065	407	7	effect	effect	NOUN
admet-3065	407	8	in	in	ADP
admet-3065	407	9	macromolecular	macromolecular	ADJ
admet-3065	407	10	therapeutics	therapeutic	NOUN
admet-3065	407	11	:	:	PUNCT
admet-3065	407	12	a	a	DET
admet-3065	407	13	review	review	NOUN
admet-3065	407	14	.	.	PUNCT
admet-3065	408	1	journal	journal	PROPN
admet-3065	408	2	of	of	ADP
admet-3065	408	3	controlled	control	VERB
admet-3065	408	4	release	release	NOUN
admet-3065	408	5	65	65	NUM
admet-3065	408	6	(	(	PUNCT
admet-3065	408	7	2000	2000	NUM
admet-3065	408	8	)	)	PUNCT
admet-3065	408	9	271	271	NUM
admet-3065	408	10	-	-	SYM
admet-3065	408	11	284	284	NUM
admet-3065	408	12	.	.	PUNCT
admet-3065	409	1	https://doi.org/10.1016/s0168-3659(99)00248-5	https://doi.org/10.1016/s0168-3659(99)00248-5	PROPN
admet-3065	410	1	[	[	X
admet-3065	410	2	3	3	NUM
admet-3065	410	3	]	]	X
admet-3065	410	4	y.	y.	PROPN
admet-3065	410	5	barenholz	barenholz	PROPN
admet-3065	410	6	.	.	PUNCT
admet-3065	411	1	doxil	doxil	NOUN
admet-3065	411	2	-	-	PUNCT
admet-3065	411	3	the	the	DET
admet-3065	411	4	first	first	ADJ
admet-3065	411	5	fda	fda	PROPN
admet-3065	411	6	-	-	PUNCT
admet-3065	411	7	approved	approve	VERB
admet-3065	411	8	nano	nano	NOUN
admet-3065	411	9	-	-	PUNCT
admet-3065	411	10	drug	drug	NOUN
admet-3065	411	11	:	:	PUNCT
admet-3065	411	12	lessons	lesson	NOUN
admet-3065	411	13	learned	learn	VERB
admet-3065	411	14	.	.	PUNCT
admet-3065	412	1	journal	journal	PROPN
admet-3065	412	2	of	of	ADP
admet-3065	412	3	controlled	control	VERB
admet-3065	412	4	release	release	NOUN
admet-3065	412	5	160	160	NUM
admet-3065	412	6	(	(	PUNCT
admet-3065	412	7	2012	2012	NUM
admet-3065	412	8	)	)	PUNCT
admet-3065	412	9	117	117	NUM
admet-3065	412	10	-	-	SYM
admet-3065	412	11	134	134	NUM
admet-3065	412	12	.	.	PUNCT
admet-3065	413	1	https://doi.org/10.1016/j.jconrel.2012.03.020	https://doi.org/10.1016/j.jconrel.2012.03.020	NOUN
admet-3065	413	2	[	[	X
admet-3065	413	3	4	4	NUM
admet-3065	413	4	]	]	X
admet-3065	413	5	s.l	s.l	PROPN
admet-3065	413	6	.	.	PROPN
admet-3065	413	7	ginn	ginn	PROPN
admet-3065	413	8	,	,	PUNCT
admet-3065	413	9	a.k	a.k	PROPN
admet-3065	413	10	.	.	PROPN
admet-3065	413	11	amaya	amaya	PROPN
admet-3065	413	12	,	,	PUNCT
admet-3065	413	13	i.e.	i.e.	X
admet-3065	413	14	alexander	alexander	PROPN
admet-3065	413	15	,	,	PUNCT
admet-3065	413	16	m.	m.	PROPN
admet-3065	413	17	edelstein	edelstein	PROPN
admet-3065	413	18	,	,	PUNCT
admet-3065	413	19	m.r	m.r	PROPN
admet-3065	413	20	.	.	PROPN
admet-3065	413	21	abedi	abedi	PROPN
admet-3065	413	22	.	.	PUNCT
admet-3065	414	1	gene	gene	NOUN
admet-3065	414	2	therapy	therapy	NOUN
admet-3065	414	3	clinical	clinical	ADJ
admet-3065	414	4	trials	trial	NOUN
admet-3065	414	5	worldwide	worldwide	ADV
admet-3065	414	6	to	to	ADP
admet-3065	414	7	2017	2017	NUM
admet-3065	414	8	:	:	PUNCT
admet-3065	414	9	an	an	DET
admet-3065	414	10	update	update	NOUN
admet-3065	414	11	.	.	PUNCT
admet-3065	415	1	journal	journal	NOUN
admet-3065	415	2	of	of	ADP
admet-3065	415	3	gene	gene	NOUN
admet-3065	415	4	medicine	medicine	NOUN
admet-3065	415	5	20	20	NUM
admet-3065	415	6	(	(	PUNCT
admet-3065	415	7	2018	2018	NUM
admet-3065	415	8	)	)	PUNCT
admet-3065	415	9	3015	3015	NUM
admet-3065	415	10	.	.	PUNCT
admet-3065	416	1	https://doi.org/10.1002/jgm.3015	https://doi.org/10.1002/jgm.3015	PROPN
admet-3065	417	1	[	[	X
admet-3065	417	2	5	5	NUM
admet-3065	417	3	]	]	X
admet-3065	417	4	j.h	j.h	PROPN
admet-3065	417	5	.	.	PROPN
admet-3065	417	6	felgner	felgner	PROPN
admet-3065	417	7	,	,	PUNCT
admet-3065	417	8	r.	r.	PROPN
admet-3065	417	9	kumar	kumar	PROPN
admet-3065	417	10	,	,	PUNCT
admet-3065	417	11	c.n	c.n	PROPN
admet-3065	417	12	.	.	PROPN
admet-3065	417	13	sridhar	sridhar	PROPN
admet-3065	417	14	,	,	PUNCT
admet-3065	417	15	c.j	c.j	PROPN
admet-3065	417	16	.	.	PROPN
admet-3065	417	17	wheeler	wheeler	NOUN
admet-3065	417	18	,	,	PUNCT
admet-3065	417	19	y.j	y.j	PROPN
admet-3065	417	20	.	.	PROPN
admet-3065	417	21	tsai	tsai	PROPN
admet-3065	417	22	,	,	PUNCT
admet-3065	417	23	r.	r.	PROPN
admet-3065	417	24	border	border	PROPN
admet-3065	417	25	.	.	PUNCT
admet-3065	418	1	enhanced	enhance	VERB
admet-3065	418	2	gene	gene	NOUN
admet-3065	418	3	delivery	delivery	NOUN
admet-3065	418	4	and	and	CCONJ
admet-3065	418	5	mechanism	mechanism	NOUN
admet-3065	418	6	studies	study	NOUN
admet-3065	418	7	with	with	ADP
admet-3065	418	8	a	a	DET
admet-3065	418	9	novel	novel	ADJ
admet-3065	418	10	series	series	NOUN
admet-3065	418	11	of	of	ADP
admet-3065	418	12	cationic	cationic	ADJ
admet-3065	418	13	lipid	lipid	NOUN
admet-3065	418	14	formulations	formulation	NOUN
admet-3065	418	15	.	.	PUNCT
admet-3065	419	1	journal	journal	NOUN
admet-3065	419	2	of	of	ADP
admet-3065	419	3	biological	biological	ADJ
admet-3065	419	4	chemistry	chemistry	NOUN
admet-3065	419	5	269	269	NUM
admet-3065	419	6	(	(	PUNCT
admet-3065	419	7	1994	1994	NUM
admet-3065	419	8	)	)	PUNCT
admet-3065	419	9	2550	2550	NUM
admet-3065	419	10	-	-	SYM
admet-3065	419	11	2561	2561	NUM
admet-3065	419	12	.	.	PUNCT
admet-3065	420	1	https://doi.org/10.1016/s0021-9258(17)41980-6	https://doi.org/10.1016/s0021-9258(17)41980-6	NOUN
admet-3065	421	1	[	[	X
admet-3065	421	2	6	6	NUM
admet-3065	421	3	]	]	X
admet-3065	421	4	s.m	s.m	PROPN
admet-3065	421	5	.	.	PROPN
admet-3065	421	6	moghimi	moghimi	PROPN
admet-3065	421	7	,	,	PUNCT
admet-3065	421	8	j.	j.	PROPN
admet-3065	421	9	szebeni	szebeni	PROPN
admet-3065	421	10	.	.	PUNCT
admet-3065	422	1	stealth	stealth	ADJ
admet-3065	422	2	liposomes	liposome	NOUN
admet-3065	422	3	and	and	CCONJ
admet-3065	422	4	long	long	ADJ
admet-3065	422	5	circulating	circulate	VERB
admet-3065	422	6	nanoparticles	nanoparticle	NOUN
admet-3065	422	7	:	:	PUNCT
admet-3065	422	8	critical	critical	ADJ
admet-3065	422	9	issues	issue	NOUN
admet-3065	422	10	in	in	ADP
admet-3065	422	11	pharmacokinetics	pharmacokinetic	NOUN
admet-3065	422	12	,	,	PUNCT
admet-3065	422	13	opsonization	opsonization	NOUN
admet-3065	422	14	and	and	CCONJ
admet-3065	422	15	protein	protein	NOUN
admet-3065	422	16	-	-	PUNCT
admet-3065	422	17	binding	bind	VERB
admet-3065	422	18	properties	property	NOUN
admet-3065	422	19	.	.	PUNCT
admet-3065	423	1	progress	progress	NOUN
admet-3065	423	2	in	in	ADP
admet-3065	423	3	lipid	lipid	ADJ
admet-3065	423	4	research	research	NOUN
admet-3065	423	5	42	42	NUM
admet-3065	423	6	(	(	PUNCT
admet-3065	423	7	2003	2003	NUM
admet-3065	423	8	)	)	PUNCT
admet-3065	423	9	463	463	NUM
admet-3065	423	10	-	-	SYM
admet-3065	423	11	478	478	NUM
admet-3065	423	12	.	.	PUNCT
admet-3065	424	1	https://doi.org/10.1016/s0163-7827(03)00033-x	https://doi.org/10.1016/s0163-7827(03)00033-x	X
admet-3065	425	1	[	[	X
admet-3065	425	2	7	7	X
admet-3065	425	3	]	]	X
admet-3065	425	4	y.	y.	PROPN
admet-3065	425	5	xu	xu	PROPN
admet-3065	425	6	,	,	PUNCT
admet-3065	425	7	f.c	f.c	PROPN
admet-3065	425	8	.	.	PROPN
admet-3065	425	9	szoka	szoka	PROPN
admet-3065	425	10	,	,	PUNCT
admet-3065	425	11	jr	jr	PROPN
admet-3065	425	12	.	.	PROPN
admet-3065	425	13	mechanism	mechanism	NOUN
admet-3065	425	14	of	of	ADP
admet-3065	425	15	dna	dna	PROPN
admet-3065	425	16	release	release	NOUN
admet-3065	425	17	from	from	ADP
admet-3065	425	18	cationic	cationic	ADJ
admet-3065	425	19	liposome	liposome	NOUN
admet-3065	425	20	/	/	SYM
admet-3065	425	21	dna	dna	NOUN
admet-3065	425	22	complexes	complex	NOUN
admet-3065	425	23	used	use	VERB
admet-3065	425	24	in	in	ADP
admet-3065	425	25	cell	cell	NOUN
admet-3065	425	26	transfection	transfection	NOUN
admet-3065	425	27	.	.	PUNCT
admet-3065	426	1	biochemistry	biochemistry	NOUN
admet-3065	426	2	35	35	NUM
admet-3065	426	3	(	(	PUNCT
admet-3065	426	4	1996	1996	NUM
admet-3065	426	5	)	)	PUNCT
admet-3065	426	6	5616	5616	NUM
admet-3065	426	7	-	-	SYM
admet-3065	426	8	5623	5623	NUM
admet-3065	426	9	.	.	PUNCT
admet-3065	426	10	https://doi.org/10.1021/bi9602019	https://doi.org/10.1021/bi9602019	X
admet-3065	427	1	[	[	X
admet-3065	427	2	8	8	NUM
admet-3065	427	3	]	]	X
admet-3065	427	4	y.	y.	PROPN
admet-3065	427	5	liu	liu	PROPN
admet-3065	427	6	,	,	PUNCT
admet-3065	427	7	j.	j.	PROPN
admet-3065	427	8	mei	mei	PROPN
admet-3065	427	9	,	,	PUNCT
admet-3065	427	10	q.	q.	PROPN
admet-3065	427	11	zhang	zhang	PROPN
admet-3065	427	12	,	,	PUNCT
admet-3065	427	13	x.	x.	PROPN
admet-3065	427	14	xiao	xiao	PROPN
admet-3065	427	15	,	,	PUNCT
admet-3065	427	16	z.	z.	PROPN
admet-3065	427	17	zhu	zhu	PROPN
admet-3065	427	18	.	.	PUNCT
admet-3065	428	1	recent	recent	ADJ
admet-3065	428	2	advances	advance	NOUN
admet-3065	428	3	in	in	ADP
admet-3065	428	4	nonviral	nonviral	ADJ
admet-3065	428	5	vectors	vector	NOUN
admet-3065	428	6	for	for	ADP
admet-3065	428	7	gene	gene	NOUN
admet-3065	428	8	delivery	delivery	NOUN
admet-3065	428	9	.	.	PUNCT
admet-3065	429	1	accounts	account	NOUN
admet-3065	429	2	of	of	ADP
admet-3065	429	3	chemical	chemical	ADJ
admet-3065	429	4	research	research	NOUN
admet-3065	429	5	45	45	NUM
admet-3065	429	6	(	(	PUNCT
admet-3065	429	7	2012	2012	NUM
admet-3065	429	8	)	)	PUNCT
admet-3065	429	9	1117	1117	NUM
admet-3065	429	10	-	-	SYM
admet-3065	429	11	1126	1126	NUM
admet-3065	429	12	.	.	PUNCT
admet-3065	430	1	https://doi.org/10.1021/ar200151	https://doi.org/10.1021/ar200151	ADV
admet-3065	430	2	m	m	PRON
admet-3065	430	3	[	[	X
admet-3065	430	4	9	9	NUM
admet-3065	430	5	]	]	X
admet-3065	430	6	g.	g.	PROPN
admet-3065	430	7	grygorieva	grygorieva	PROPN
admet-3065	430	8	,	,	PUNCT
admet-3065	430	9	d.	d.	PROPN
admet-3065	430	10	pylypenko	pylypenko	PROPN
admet-3065	430	11	,	,	PUNCT
admet-3065	430	12	y.	y.	PROPN
admet-3065	430	13	krasnopolsky	krasnopolsky	PROPN
admet-3065	430	14	.	.	PUNCT
admet-3065	431	1	liposomes	liposome	NOUN
admet-3065	431	2	:	:	PUNCT
admet-3065	431	3	from	from	ADP
admet-3065	431	4	august	august	PROPN
admet-3065	431	5	wassermann	wassermann	PROPN
admet-3065	431	6	to	to	ADP
admet-3065	431	7	vaccines	vaccine	NOUN
admet-3065	431	8	against	against	ADP
admet-3065	431	9	covid-19	covid-19	PROPN
admet-3065	431	10	.	.	PROPN
admet-3065	431	11	admet	admet	PROPN
admet-3065	431	12	and	and	CCONJ
admet-3065	431	13	dmpk	dmpk	X
admet-3065	431	14	11	11	NUM
admet-3065	431	15	(	(	PUNCT
admet-3065	431	16	2023	2023	NUM
admet-3065	431	17	)	)	PUNCT
admet-3065	431	18	487	487	NUM
admet-3065	431	19	-	-	SYM
admet-3065	431	20	497	497	NUM
admet-3065	431	21	.	.	PUNCT
admet-3065	431	22	https://doi.org/10.5599/admet.1926	https://doi.org/10.5599/admet.1926	NOUN
admet-3065	432	1	[	[	X
admet-3065	432	2	10	10	NUM
admet-3065	432	3	]	]	X
admet-3065	432	4	p.	p.	PROPN
admet-3065	432	5	liu	liu	PROPN
admet-3065	432	6	,	,	PUNCT
admet-3065	432	7	g.	g.	PROPN
admet-3065	432	8	chen	chen	PROPN
admet-3065	432	9	,	,	PUNCT
admet-3065	432	10	j.	j.	PROPN
admet-3065	432	11	zhang	zhang	PROPN
admet-3065	432	12	.	.	PUNCT
admet-3065	433	1	a	a	DET
admet-3065	433	2	review	review	NOUN
admet-3065	433	3	of	of	ADP
admet-3065	433	4	liposomes	liposome	NOUN
admet-3065	433	5	as	as	ADP
admet-3065	433	6	a	a	DET
admet-3065	433	7	drug	drug	NOUN
admet-3065	433	8	delivery	delivery	NOUN
admet-3065	433	9	system	system	NOUN
admet-3065	433	10	:	:	PUNCT
admet-3065	433	11	current	current	ADJ
admet-3065	433	12	status	status	NOUN
admet-3065	433	13	of	of	ADP
admet-3065	433	14	approved	approve	VERB
admet-3065	433	15	products	product	NOUN
admet-3065	433	16	,	,	PUNCT
admet-3065	433	17	regulatory	regulatory	ADJ
admet-3065	433	18	environments	environment	NOUN
admet-3065	433	19	,	,	PUNCT
admet-3065	433	20	and	and	CCONJ
admet-3065	433	21	future	future	ADJ
admet-3065	433	22	perspectives	perspective	NOUN
admet-3065	433	23	.	.	PUNCT
admet-3065	434	1	molecules	molecule	NOUN
admet-3065	434	2	27	27	NUM
admet-3065	434	3	(	(	PUNCT
admet-3065	434	4	2022	2022	NUM
admet-3065	434	5	)	)	PUNCT
admet-3065	434	6	1372	1372	NUM
admet-3065	434	7	.	.	PUNCT
admet-3065	435	1	https://doi.org/10.3390/molecules27041372	https://doi.org/10.3390/molecules27041372	PROPN
admet-3065	435	2	[	[	X
admet-3065	435	3	11	11	NUM
admet-3065	435	4	]	]	PUNCT
admet-3065	435	5	a.	a.	NOUN
admet-3065	435	6	jesorka	jesorka	PROPN
admet-3065	435	7	,	,	PUNCT
admet-3065	435	8	o.	o.	PROPN
admet-3065	435	9	orwar	orwar	PROPN
admet-3065	435	10	.	.	PUNCT
admet-3065	436	1	liposomes	liposome	NOUN
admet-3065	436	2	:	:	PUNCT
admet-3065	436	3	technologies	technology	NOUN
admet-3065	436	4	and	and	CCONJ
admet-3065	436	5	analytical	analytical	ADJ
admet-3065	436	6	applications	application	NOUN
admet-3065	436	7	.	.	PUNCT
admet-3065	437	1	annual	annual	ADJ
admet-3065	437	2	review	review	NOUN
admet-3065	437	3	of	of	ADP
admet-3065	437	4	analytical	analytical	ADJ
admet-3065	437	5	chemistry	chemistry	NOUN
admet-3065	437	6	1	1	NUM
admet-3065	437	7	(	(	PUNCT
admet-3065	437	8	2008	2008	NUM
admet-3065	437	9	)	)	PUNCT
admet-3065	437	10	801	801	NUM
admet-3065	437	11	-	-	SYM
admet-3065	437	12	832	832	NUM
admet-3065	437	13	.	.	PUNCT
admet-3065	437	14	https://doi.org/10.1146/annurev.anchem.1.031207.112747	https://doi.org/10.1146/annurev.anchem.1.031207.112747	PUNCT
admet-3065	438	1	[	[	X
admet-3065	438	2	12	12	NUM
admet-3065	438	3	]	]	X
admet-3065	438	4	w.	w.	PROPN
admet-3065	438	5	mehnert	mehnert	PROPN
admet-3065	438	6	,	,	PUNCT
admet-3065	438	7	k.	k.	PROPN
admet-3065	438	8	mäder	mäder	PROPN
admet-3065	438	9	.	.	PUNCT
admet-3065	439	1	solid	solid	ADJ
admet-3065	439	2	lipid	lipid	ADJ
admet-3065	439	3	nanoparticles	nanoparticle	NOUN
admet-3065	439	4	:	:	PUNCT
admet-3065	439	5	production	production	NOUN
admet-3065	439	6	,	,	PUNCT
admet-3065	439	7	characterization	characterization	NOUN
admet-3065	439	8	and	and	CCONJ
admet-3065	439	9	applications	application	NOUN
admet-3065	439	10	.	.	PUNCT
admet-3065	440	1	advanced	advanced	ADJ
admet-3065	440	2	drug	drug	NOUN
admet-3065	440	3	delivery	delivery	NOUN
admet-3065	440	4	reviews	review	VERB
admet-3065	440	5	47	47	NUM
admet-3065	440	6	(	(	PUNCT
admet-3065	440	7	2001	2001	NUM
admet-3065	440	8	)	)	PUNCT
admet-3065	440	9	165	165	NUM
admet-3065	440	10	-	-	SYM
admet-3065	440	11	196	196	NUM
admet-3065	440	12	.	.	PUNCT
admet-3065	441	1	https://doi.org/10.1016/s0169-409x(01)00105-3	https://doi.org/10.1016/s0169-409x(01)00105-3	PROPN
admet-3065	442	1	[	[	X
admet-3065	442	2	13	13	NUM
admet-3065	442	3	]	]	X
admet-3065	442	4	t.m	t.m	PROPN
admet-3065	442	5	.	.	PROPN
admet-3065	442	6	allen	allen	PROPN
admet-3065	442	7	,	,	PUNCT
admet-3065	442	8	p.r	p.r	PROPN
admet-3065	442	9	.	.	PROPN
admet-3065	442	10	cullis	cullis	PROPN
admet-3065	442	11	.	.	PUNCT
admet-3065	443	1	liposomal	liposomal	PROPN
admet-3065	443	2	drug	drug	PROPN
admet-3065	443	3	delivery	delivery	NOUN
admet-3065	443	4	systems	system	NOUN
admet-3065	443	5	:	:	PUNCT
admet-3065	443	6	from	from	ADP
admet-3065	443	7	concept	concept	NOUN
admet-3065	443	8	to	to	ADP
admet-3065	443	9	clinical	clinical	ADJ
admet-3065	443	10	applications	application	NOUN
admet-3065	443	11	.	.	PUNCT
admet-3065	444	1	advanced	advanced	ADJ
admet-3065	444	2	drug	drug	NOUN
admet-3065	444	3	delivery	delivery	NOUN
admet-3065	444	4	reviews	review	NOUN
admet-3065	444	5	65	65	NUM
admet-3065	444	6	(	(	PUNCT
admet-3065	444	7	2013	2013	NUM
admet-3065	444	8	)	)	PUNCT
admet-3065	444	9	36	36	NUM
admet-3065	444	10	-	-	SYM
admet-3065	444	11	48	48	NUM
admet-3065	444	12	.	.	PUNCT
admet-3065	445	1	https://doi.org/10.1016/j.addr.2012.09.037	https://doi.org/10.1016/j.addr.2012.09.037	NOUN
admet-3065	445	2	[	[	X
admet-3065	445	3	14	14	NUM
admet-3065	445	4	]	]	X
admet-3065	445	5	f.	f.	PROPN
admet-3065	445	6	ashoori	ashoori	PROPN
admet-3065	445	7	,	,	PUNCT
admet-3065	445	8	b.	b.	PROPN
admet-3065	445	9	hajipour	hajipour	PROPN
admet-3065	445	10	-	-	PUNCT
admet-3065	445	11	verdom	verdom	NOUN
admet-3065	445	12	,	,	PUNCT
admet-3065	445	13	m.	m.	NOUN
admet-3065	445	14	satari	satari	NOUN
admet-3065	445	15	,	,	PUNCT
admet-3065	445	16	p.	p.	PROPN
admet-3065	445	17	abdolmaleki	abdolmaleki	PROPN
admet-3065	445	18	.	.	PUNCT
admet-3065	446	1	polyethylenimine	polyethylenimine	NOUN
admet-3065	446	2	-	-	PUNCT
admet-3065	446	3	based	base	VERB
admet-3065	446	4	iron	iron	NOUN
admet-3065	446	5	oxide	oxide	NOUN
admet-3065	446	6	nanoparticles	nanoparticle	NOUN
admet-3065	446	7	enhance	enhance	VERB
admet-3065	446	8	cisplatin	cisplatin	NOUN
admet-3065	446	9	toxicity	toxicity	NOUN
admet-3065	446	10	in	in	ADP
admet-3065	446	11	ovarian	ovarian	ADJ
admet-3065	446	12	cancer	cancer	NOUN
admet-3065	446	13	cells	cell	NOUN
admet-3065	446	14	in	in	ADP
admet-3065	446	15	the	the	DET
admet-3065	446	16	presence	presence	NOUN
admet-3065	446	17	of	of	ADP
admet-3065	446	18	a	a	DET
admet-3065	446	19	static	static	ADJ
admet-3065	446	20	magnetic	magnetic	ADJ
admet-3065	446	21	field	field	NOUN
admet-3065	446	22	.	.	PUNCT
admet-3065	447	1	frontiers	frontier	NOUN
admet-3065	447	2	in	in	ADP
admet-3065	447	3	oncology	oncology	NOUN
admet-3065	447	4	13	13	NUM
admet-3065	447	5	(	(	PUNCT
admet-3065	447	6	2023	2023	NUM
admet-3065	447	7	)	)	PUNCT
admet-3065	447	8	1217800	1217800	NUM
admet-3065	447	9	.	.	PUNCT
admet-3065	448	1	https://doi.org/10.3389/fonc.2023.1217800	https://doi.org/10.3389/fonc.2023.1217800	PROPN
admet-3065	448	2	[	[	X
admet-3065	448	3	15	15	NUM
admet-3065	448	4	]	]	X
admet-3065	448	5	m.	m.	NOUN
admet-3065	448	6	satari	satari	PROPN
admet-3065	448	7	,	,	PUNCT
admet-3065	448	8	b.	b.	PROPN
admet-3065	448	9	hajipoor	hajipoor	PROPN
admet-3065	448	10	,	,	PUNCT
admet-3065	448	11	s.	s.	PROPN
admet-3065	448	12	hosseinkhani	hosseinkhani	PROPN
admet-3065	448	13	,	,	PUNCT
admet-3065	448	14	p.	p.	PROPN
admet-3065	448	15	abdolmaleki	abdolmaleki	PROPN
admet-3065	448	16	.	.	PUNCT
admet-3065	449	1	investigating	investigate	VERB
admet-3065	449	2	the	the	DET
admet-3065	449	3	effect	effect	NOUN
admet-3065	449	4	of	of	ADP
admet-3065	449	5	50	50	NUM
admet-3065	449	6	hz	hz	VERB
admet-3065	449	7	alternating	alternate	VERB
admet-3065	449	8	magnetic	magnetic	ADJ
admet-3065	449	9	field	field	NOUN
admet-3065	449	10	on	on	ADP
admet-3065	449	11	nucleic	nucleic	ADJ
admet-3065	449	12	acid	acid	NOUN
admet-3065	449	13	delivery	delivery	NOUN
admet-3065	449	14	by	by	ADP
admet-3065	449	15	magnetofection	magnetofection	NOUN
admet-3065	449	16	method	method	NOUN
admet-3065	449	17	.	.	PUNCT
admet-3065	450	1	modares	modare	NOUN
admet-3065	450	2	journal	journal	PROPN
admet-3065	450	3	of	of	ADP
admet-3065	450	4	biotechnology	biotechnology	NOUN
admet-3065	450	5	15	15	NUM
admet-3065	450	6	(	(	PUNCT
admet-3065	450	7	2024	2024	NUM
admet-3065	450	8	)	)	PUNCT
admet-3065	450	9	22721	22721	NUM
admet-3065	450	10	.	.	PUNCT
admet-3065	451	1	https://biot.modares.ac.ir/article_22721_en.html	https://biot.modares.ac.ir/article_22721_en.html	PROPN
admet-3065	452	1	[	[	X
admet-3065	452	2	16	16	NUM
admet-3065	452	3	]	]	PUNCT
admet-3065	452	4	m.	m.	PROPN
admet-3065	452	5	kazemi	kazemi	PROPN
admet-3065	452	6	-	-	PUNCT
admet-3065	452	7	ashtiyani	ashtiyani	PROPN
admet-3065	452	8	,	,	PUNCT
admet-3065	452	9	b.	b.	PROPN
admet-3065	452	10	hajipour	hajipour	NOUN
admet-3065	452	11	-	-	PUNCT
admet-3065	452	12	verdom	verdom	NOUN
admet-3065	452	13	,	,	PUNCT
admet-3065	452	14	m.	m.	NOUN
admet-3065	452	15	satari	satari	NOUN
admet-3065	452	16	,	,	PUNCT
admet-3065	452	17	p.	p.	PROPN
admet-3065	452	18	abdolmaleki	abdolmaleki	PROPN
admet-3065	452	19	,	,	PUNCT
admet-3065	452	20	s.	s.	PROPN
admet-3065	452	21	hosseinkhani	hosseinkhani	PROPN
admet-3065	452	22	,	,	PUNCT
admet-3065	452	23	h.	h.	PROPN
admet-3065	452	24	shaki	shaki	PROPN
admet-3065	452	25	.	.	PUNCT
admet-3065	453	1	estimating	estimate	VERB
admet-3065	453	2	the	the	DET
admet-3065	453	3	two	two	NUM
admet-3065	453	4	graph	graph	NOUN
admet-3065	453	5	dextran	dextran	NOUN
admet-3065	453	6	-	-	PUNCT
admet-3065	453	7	stearic	stearic	NOUN
admet-3065	453	8	acid	acid	NOUN
admet-3065	453	9	-	-	PUNCT
admet-3065	453	10	spermine	spermine	NOUN
admet-3065	453	11	polymers	polymer	NOUN
admet-3065	453	12	based	base	VERB
admet-3065	453	13	on	on	ADP
admet-3065	453	14	iron	iron	NOUN
admet-3065	453	15	oxide	oxide	NOUN
admet-3065	453	16	nanoparticles	nanoparticle	NOUN
admet-3065	453	17	as	as	ADP
admet-3065	453	18	carrier	carrier	NOUN
admet-3065	453	19	for	for	ADP
admet-3065	453	20	gene	gene	NOUN
admet-3065	453	21	delivery	delivery	NOUN
admet-3065	453	22	.	.	PUNCT
admet-3065	454	1	biopolymers	biopolymer	NOUN
admet-3065	454	2	113	113	NUM
admet-3065	454	3	(	(	PUNCT
admet-3065	454	4	2022	2022	NUM
admet-3065	454	5	)	)	PUNCT
admet-3065	454	6	23491	23491	NUM
admet-3065	454	7	.	.	PUNCT
admet-3065	455	1	https://doi.org/10.1002/bip.23491	https://doi.org/10.1002/bip.23491	PROPN
admet-3065	456	1	[	[	X
admet-3065	456	2	17	17	NUM
admet-3065	456	3	]	]	X
admet-3065	456	4	v.p	v.p	PROPN
admet-3065	456	5	.	.	PROPN
admet-3065	456	6	torchilin	torchilin	PROPN
admet-3065	456	7	.	.	PUNCT
admet-3065	457	1	recent	recent	ADJ
admet-3065	457	2	advances	advance	NOUN
admet-3065	457	3	with	with	ADP
admet-3065	457	4	liposomes	liposome	NOUN
admet-3065	457	5	as	as	ADP
admet-3065	457	6	pharmaceutical	pharmaceutical	NOUN
admet-3065	457	7	carriers	carrier	NOUN
admet-3065	457	8	.	.	PUNCT
admet-3065	458	1	nature	nature	NOUN
admet-3065	458	2	reviews	review	VERB
admet-3065	458	3	drug	drug	NOUN
admet-3065	458	4	discovery	discovery	NOUN
admet-3065	458	5	4	4	NUM
admet-3065	458	6	(	(	PUNCT
admet-3065	458	7	2005	2005	NUM
admet-3065	458	8	)	)	PUNCT
admet-3065	458	9	145	145	NUM
admet-3065	458	10	-	-	SYM
admet-3065	458	11	160	160	NUM
admet-3065	458	12	.	.	PUNCT
admet-3065	458	13	https://doi.org/10.1073/pnas.84.21.7413	https://doi.org/10.1073/pnas.84.21.7413	PRON
admet-3065	459	1	[	[	X
admet-3065	459	2	18	18	NUM
admet-3065	459	3	]	]	X
admet-3065	459	4	d.d	d.d	PROPN
admet-3065	459	5	.	.	PROPN
admet-3065	459	6	lasic	lasic	PROPN
admet-3065	459	7	,	,	PUNCT
admet-3065	459	8	n.s	n.s	PROPN
admet-3065	459	9	.	.	PROPN
admet-3065	459	10	templeton	templeton	PROPN
admet-3065	459	11	.	.	PUNCT
admet-3065	460	1	liposomes	liposome	NOUN
admet-3065	460	2	in	in	ADP
admet-3065	460	3	gene	gene	NOUN
admet-3065	460	4	therapy	therapy	NOUN
admet-3065	460	5	.	.	PUNCT
admet-3065	461	1	advanced	advanced	ADJ
admet-3065	461	2	drug	drug	NOUN
admet-3065	461	3	delivery	delivery	NOUN
admet-3065	461	4	reviews	review	NOUN
admet-3065	461	5	20	20	NUM
admet-3065	461	6	(	(	PUNCT
admet-3065	461	7	1996	1996	NUM
admet-3065	461	8	)	)	PUNCT
admet-3065	461	9	221	221	NUM
admet-3065	461	10	-	-	SYM
admet-3065	461	11	266	266	NUM
admet-3065	461	12	.	.	PUNCT
admet-3065	462	1	https://doi.org/10.1038/sj.gt.3302337	https://doi.org/10.1038/sj.gt.3302337	PROPN
admet-3065	462	2	[	[	X
admet-3065	462	3	19	19	NUM
admet-3065	462	4	]	]	X
admet-3065	462	5	p.l	p.l	PROPN
admet-3065	462	6	.	.	PROPN
admet-3065	462	7	felgner	felgner	PROPN
admet-3065	462	8	,	,	PUNCT
admet-3065	462	9	t.r	t.r	PROPN
admet-3065	462	10	.	.	PROPN
admet-3065	462	11	gadek	gadek	PROPN
admet-3065	462	12	,	,	PUNCT
admet-3065	462	13	m.	m.	NOUN
admet-3065	462	14	holm	holm	PROPN
admet-3065	462	15	,	,	PUNCT
admet-3065	462	16	r.	r.	PROPN
admet-3065	462	17	roman	roman	PROPN
admet-3065	462	18	,	,	PUNCT
admet-3065	462	19	h.w	h.w	PROPN
admet-3065	462	20	.	.	PROPN
admet-3065	462	21	chan	chan	PROPN
admet-3065	462	22	,	,	PUNCT
admet-3065	462	23	m.	m.	PROPN
admet-3065	462	24	wenz	wenz	PROPN
admet-3065	462	25	.	.	PUNCT
admet-3065	463	1	lipofection	lipofection	NOUN
admet-3065	463	2	:	:	PUNCT
admet-3065	463	3	a	a	DET
admet-3065	463	4	highly	highly	ADV
admet-3065	463	5	efficient	efficient	ADJ
admet-3065	463	6	,	,	PUNCT
admet-3065	463	7	lipid	lipid	NOUN
admet-3065	463	8	-	-	PUNCT
admet-3065	463	9	mediated	mediate	VERB
admet-3065	463	10	dna	dna	NOUN
admet-3065	463	11	-	-	PUNCT
admet-3065	463	12	transfection	transfection	NOUN
admet-3065	463	13	procedure	procedure	NOUN
admet-3065	463	14	.	.	PUNCT
admet-3065	464	1	proceedings	proceeding	NOUN
admet-3065	464	2	of	of	ADP
admet-3065	464	3	the	the	DET
admet-3065	464	4	national	national	PROPN
admet-3065	464	5	academy	academy	PROPN
admet-3065	464	6	of	of	ADP
admet-3065	464	7	sciences	sciences	PROPN
admet-3065	464	8	of	of	ADP
admet-3065	464	9	the	the	DET
admet-3065	464	10	united	united	PROPN
admet-3065	464	11	states	states	PROPN
admet-3065	464	12	of	of	ADP
admet-3065	464	13	america	america	PROPN
admet-3065	464	14	84	84	NUM
admet-3065	464	15	(	(	PUNCT
admet-3065	464	16	1987	1987	NUM
admet-3065	464	17	)	)	PUNCT
admet-3065	464	18	7413	7413	NUM
admet-3065	464	19	-	-	SYM
admet-3065	464	20	7417	7417	NUM
admet-3065	464	21	.	.	PUNCT
admet-3065	465	1	https://doi.org/10.1073/pnas.84.21.7413	https://doi.org/10.1073/pnas.84.21.7413	PRON
admet-3065	466	1	[	[	X
admet-3065	466	2	20	20	NUM
admet-3065	466	3	]	]	X
admet-3065	466	4	d.j	d.j	PROPN
admet-3065	466	5	.	.	PROPN
admet-3065	466	6	wells	wells	PROPN
admet-3065	466	7	.	.	PUNCT
admet-3065	467	1	gene	gene	NOUN
admet-3065	467	2	therapy	therapy	NOUN
admet-3065	467	3	progress	progress	NOUN
admet-3065	467	4	and	and	CCONJ
admet-3065	467	5	prospects	prospect	NOUN
admet-3065	467	6	:	:	PUNCT
admet-3065	467	7	electroporation	electroporation	NOUN
admet-3065	467	8	and	and	CCONJ
admet-3065	467	9	other	other	ADJ
admet-3065	467	10	physical	physical	ADJ
admet-3065	467	11	methods	method	NOUN
admet-3065	467	12	.	.	PUNCT
admet-3065	468	1	gene	gene	NOUN
admet-3065	468	2	therapy	therapy	NOUN
admet-3065	468	3	11	11	NUM
admet-3065	468	4	(	(	PUNCT
admet-3065	468	5	2004	2004	NUM
admet-3065	468	6	)	)	PUNCT
admet-3065	468	7	1363	1363	NUM
admet-3065	468	8	-	-	SYM
admet-3065	468	9	1369	1369	NUM
admet-3065	468	10	.	.	PUNCT
admet-3065	469	1	https://doi.org/10.1038/sj.gt.3302337	https://doi.org/10.1038/sj.gt.3302337	PROPN
admet-3065	469	2	[	[	X
admet-3065	469	3	21	21	NUM
admet-3065	469	4	]	]	X
admet-3065	469	5	h.	h.	PROPN
admet-3065	469	6	yin	yin	PROPN
admet-3065	469	7	,	,	PUNCT
admet-3065	469	8	r.l	r.l	PROPN
admet-3065	469	9	.	.	PROPN
admet-3065	469	10	kanasty	kanasty	PROPN
admet-3065	469	11	,	,	PUNCT
admet-3065	469	12	a.a	a.a	PROPN
admet-3065	469	13	.	.	PROPN
admet-3065	469	14	eltoukhy	eltoukhy	PROPN
admet-3065	469	15	,	,	PUNCT
admet-3065	469	16	a.j	a.j	PROPN
admet-3065	469	17	.	.	PROPN
admet-3065	469	18	vegas	vegas	PROPN
admet-3065	469	19	,	,	PUNCT
admet-3065	469	20	j.r	j.r	PROPN
admet-3065	469	21	.	.	PROPN
admet-3065	469	22	dorkin	dorkin	PROPN
admet-3065	469	23	,	,	PUNCT
admet-3065	469	24	d.g	d.g	PROPN
admet-3065	469	25	.	.	PROPN
admet-3065	469	26	anderson	anderson	PROPN
admet-3065	469	27	.	.	PUNCT
admet-3065	470	1	non	non	ADJ
admet-3065	470	2	-	-	ADJ
admet-3065	470	3	viral	viral	ADJ
admet-3065	470	4	vectors	vector	NOUN
admet-3065	470	5	for	for	ADP
admet-3065	470	6	genebased	genebased	ADJ
admet-3065	470	7	therapy	therapy	NOUN
admet-3065	470	8	.	.	PUNCT
admet-3065	471	1	nature	nature	NOUN
admet-3065	471	2	reviews	review	VERB
admet-3065	471	3	genetics	genetic	NOUN
admet-3065	471	4	15	15	NUM
admet-3065	471	5	(	(	PUNCT
admet-3065	471	6	2014	2014	NUM
admet-3065	471	7	)	)	PUNCT
admet-3065	471	8	541	541	NUM
admet-3065	471	9	-	-	SYM
admet-3065	471	10	555	555	NUM
admet-3065	471	11	.	.	PUNCT
admet-3065	472	1	https://doi.org/10.1038/nrg3763	https://doi.org/10.1038/nrg3763	PROPN
admet-3065	472	2	https://doi.org/10.1016/s0168-3659(99)00248-5	https://doi.org/10.1016/s0168-3659(99)00248-5	PROPN
admet-3065	472	3	.	.	PUNCT
admet-3065	473	1	https://doi.org/10.1016/j.jconrel.2012.03.020	https://doi.org/10.1016/j.jconrel.2012.03.020	PROPN
admet-3065	473	2	https://doi.org/10.1002/jgm.3015	https://doi.org/10.1002/jgm.3015	PROPN
admet-3065	473	3	.	.	PUNCT
admet-3065	474	1	https://doi.org/10.1016/s0021-9258(17)41980-6	https://doi.org/10.1016/s0021-9258(17)41980-6	PROPN
admet-3065	474	2	https://doi.org/10.1016/s0163-7827(03)00033-x	https://doi.org/10.1016/s0163-7827(03)00033-x	PROPN
admet-3065	474	3	.	.	PUNCT
admet-3065	475	1	https://doi.org/10.1021/bi9602019	https://doi.org/10.1021/bi9602019	X
admet-3065	475	2	.	.	PUNCT
admet-3065	476	1	https://doi.org/10.1021/ar200151	https://doi.org/10.1021/ar200151	ADP
admet-3065	476	2	m	m	VERB
admet-3065	476	3	https://doi.org/10.5599/admet.1926	https://doi.org/10.5599/admet.1926	NOUN
admet-3065	476	4	https://doi.org/10.3390/molecules27041372	https://doi.org/10.3390/molecules27041372	PROPN
admet-3065	476	5	.	.	PUNCT
admet-3065	477	1	https://doi.org/10.1146/annurev.anchem.1.031207.112747	https://doi.org/10.1146/annurev.anchem.1.031207.112747	PROPN
admet-3065	477	2	https://doi.org/10.1016/s0169-409x(01)00105-3	https://doi.org/10.1016/s0169-409x(01)00105-3	PROPN
admet-3065	477	3	.	.	PUNCT
admet-3065	478	1	https://doi.org/10.1016/j.addr.2012.09.037	https://doi.org/10.1016/j.addr.2012.09.037	NOUN
admet-3065	478	2	.	.	PUNCT
admet-3065	479	1	https://doi.org/10.3389/fonc.2023.1217800	https://doi.org/10.3389/fonc.2023.1217800	PROPN
admet-3065	479	2	https://biot.modares.ac.ir/article_22721_en.html	https://biot.modares.ac.ir/article_22721_en.html	PROPN
admet-3065	479	3	https://doi.org/10.1002/bip.23491	https://doi.org/10.1002/bip.23491	PROPN
admet-3065	479	4	https://doi.org/10.1073/pnas.84.21.7413	https://doi.org/10.1073/pnas.84.21.7413	PROPN
admet-3065	479	5	.	.	PUNCT
admet-3065	480	1	https://doi.org/10.1038/sj.gt.3302337	https://doi.org/10.1038/sj.gt.3302337	PROPN
admet-3065	480	2	.	.	PUNCT
admet-3065	481	1	https://doi.org/10.1073/pnas.84.21.7413	https://doi.org/10.1073/pnas.84.21.7413	NOUN
admet-3065	481	2	.	.	PUNCT
admet-3065	482	1	https://doi.org/10.1038/sj.gt.3302337	https://doi.org/10.1038/sj.gt.3302337	PROPN
admet-3065	482	2	https://doi.org/10.1038/nrg3763	https://doi.org/10.1038/nrg3763	PROPN
admet-3065	482	3	.	.	PUNCT
admet-3065	483	1	e.	e.	PROPN
admet-3065	483	2	j.	j.	PROPN
admet-3065	483	3	saleh	saleh	PROPN
admet-3065	483	4	et	et	PROPN
admet-3065	483	5	al	al	PROPN
admet-3065	483	6	.	.	PROPN
admet-3065	483	7	admet	admet	PROPN
admet-3065	483	8	&	&	CCONJ
admet-3065	483	9	dmpk	dmpk	PROPN
admet-3065	483	10	00(0	00(0	PROPN
admet-3065	483	11	)	)	PUNCT
admet-3065	483	12	(	(	PUNCT
admet-3065	483	13	2025	2025	NUM
admet-3065	483	14	)	)	PUNCT
admet-3065	483	15	3065	3065	NUM
admet-3065	483	16	20	20	NUM
admet-3065	484	1	[	[	SYM
admet-3065	484	2	22	22	NUM
admet-3065	484	3	]	]	SYM
admet-3065	484	4	c.m	c.m	PROPN
admet-3065	484	5	.	.	PROPN
admet-3065	484	6	newman	newman	PROPN
admet-3065	484	7	,	,	PUNCT
admet-3065	484	8	t.	t.	NOUN
admet-3065	484	9	bettinger	bettinger	NOUN
admet-3065	484	10	.	.	PUNCT
admet-3065	485	1	gene	gene	NOUN
admet-3065	485	2	therapy	therapy	NOUN
admet-3065	485	3	progress	progress	NOUN
admet-3065	485	4	and	and	CCONJ
admet-3065	485	5	prospects	prospect	NOUN
admet-3065	485	6	:	:	PUNCT
admet-3065	485	7	ultrasound	ultrasound	ADJ
admet-3065	485	8	for	for	ADP
admet-3065	485	9	gene	gene	NOUN
admet-3065	485	10	transfer	transfer	NOUN
admet-3065	485	11	.	.	PUNCT
admet-3065	486	1	gene	gene	NOUN
admet-3065	486	2	therapy	therapy	NOUN
admet-3065	486	3	14	14	NUM
admet-3065	486	4	(	(	PUNCT
admet-3065	486	5	2007	2007	NUM
admet-3065	486	6	)	)	PUNCT
admet-3065	486	7	465	465	NUM
admet-3065	486	8	-	-	SYM
admet-3065	486	9	475	475	NUM
admet-3065	486	10	.	.	PUNCT
admet-3065	487	1	https://doi.org/10.1038/sj.gt.3302925	https://doi.org/10.1038/sj.gt.3302925	PROPN
admet-3065	488	1	[	[	X
admet-3065	488	2	23	23	NUM
admet-3065	488	3	]	]	PUNCT
admet-3065	488	4	t.	t.	NOUN
admet-3065	488	5	friedmann	friedmann	PROPN
admet-3065	488	6	,	,	PUNCT
admet-3065	488	7	r.	r.	PROPN
admet-3065	488	8	roblin	roblin	PROPN
admet-3065	488	9	.	.	PUNCT
admet-3065	489	1	gene	gene	NOUN
admet-3065	489	2	therapy	therapy	NOUN
admet-3065	489	3	for	for	ADP
admet-3065	489	4	human	human	ADJ
admet-3065	489	5	genetic	genetic	ADJ
admet-3065	489	6	disease	disease	NOUN
admet-3065	489	7	?	?	PUNCT
admet-3065	490	1	science	science	NOUN
admet-3065	490	2	175	175	NUM
admet-3065	490	3	(	(	PUNCT
admet-3065	490	4	1972	1972	NUM
admet-3065	490	5	)	)	PUNCT
admet-3065	490	6	949	949	NUM
admet-3065	490	7	-	-	SYM
admet-3065	490	8	955	955	NUM
admet-3065	490	9	.	.	PUNCT
admet-3065	491	1	https://doi.org/10.1126/science.175.4025.949	https://doi.org/10.1126/science.175.4025.949	NOUN
admet-3065	492	1	[	[	X
admet-3065	492	2	24	24	NUM
admet-3065	492	3	]	]	X
admet-3065	492	4	n.	n.	NOUN
admet-3065	492	5	sayed	say	VERB
admet-3065	492	6	,	,	PUNCT
admet-3065	492	7	p.	p.	NOUN
admet-3065	492	8	allawadhi	allawadhi	PROPN
admet-3065	492	9	,	,	PUNCT
admet-3065	492	10	a.	a.	NOUN
admet-3065	492	11	khurana	khurana	PROPN
admet-3065	492	12	,	,	PUNCT
admet-3065	493	1	v.	v.	ADP
admet-3065	493	2	singh	singh	PROPN
admet-3065	493	3	,	,	PUNCT
admet-3065	493	4	u.	u.	PROPN
admet-3065	493	5	navik	navik	PROPN
admet-3065	493	6	,	,	PUNCT
admet-3065	493	7	s.k	s.k	PROPN
admet-3065	493	8	.	.	PROPN
admet-3065	493	9	pasumarthi	pasumarthi	PROPN
admet-3065	493	10	,	,	PUNCT
admet-3065	493	11	i.	i.	PROPN
admet-3065	493	12	khurana	khurana	PROPN
admet-3065	493	13	,	,	PUNCT
admet-3065	493	14	a.k	a.k	PROPN
admet-3065	493	15	.	.	PROPN
admet-3065	493	16	banothu	banothu	PROPN
admet-3065	493	17	,	,	PUNCT
admet-3065	493	18	r.	r.	PROPN
admet-3065	493	19	weiskirchen	weiskirchen	PROPN
admet-3065	493	20	,	,	PUNCT
admet-3065	493	21	k.k	k.k	PROPN
admet-3065	493	22	.	.	PROPN
admet-3065	493	23	bharani	bharani	PROPN
admet-3065	493	24	.	.	PUNCT
admet-3065	494	1	gene	gene	NOUN
admet-3065	494	2	therapy	therapy	NOUN
admet-3065	494	3	:	:	PUNCT
admet-3065	494	4	comprehensive	comprehensive	ADJ
admet-3065	494	5	overview	overview	NOUN
admet-3065	494	6	and	and	CCONJ
admet-3065	494	7	therapeutic	therapeutic	ADJ
admet-3065	494	8	applications	application	NOUN
admet-3065	494	9	.	.	PUNCT
admet-3065	495	1	life	life	NOUN
admet-3065	495	2	sciences	science	VERB
admet-3065	495	3	294	294	NUM
admet-3065	495	4	(	(	PUNCT
admet-3065	495	5	2022	2022	NUM
admet-3065	495	6	)	)	PUNCT
admet-3065	495	7	120375	120375	NUM
admet-3065	495	8	.	.	PUNCT
admet-3065	496	1	https://doi.org/10.1016/j.lfs.2022.120375	https://doi.org/10.1016/j.lfs.2022.120375	PUNCT
admet-3065	497	1	[	[	X
admet-3065	497	2	25	25	NUM
admet-3065	497	3	]	]	X
admet-3065	497	4	k.a	k.a	PROPN
admet-3065	497	5	.	.	PROPN
admet-3065	497	6	high	high	PROPN
admet-3065	497	7	,	,	PUNCT
admet-3065	497	8	m.g	m.g	PROPN
admet-3065	497	9	.	.	PROPN
admet-3065	497	10	roncarolo	roncarolo	PROPN
admet-3065	497	11	.	.	PUNCT
admet-3065	498	1	gene	gene	NOUN
admet-3065	498	2	therapy	therapy	NOUN
admet-3065	498	3	.	.	PUNCT
admet-3065	499	1	new	new	PROPN
admet-3065	499	2	england	england	PROPN
admet-3065	499	3	journal	journal	PROPN
admet-3065	499	4	of	of	ADP
admet-3065	499	5	medicine	medicine	NOUN
admet-3065	499	6	381	381	NUM
admet-3065	499	7	(	(	PUNCT
admet-3065	499	8	2019	2019	NUM
admet-3065	499	9	)	)	PUNCT
admet-3065	499	10	455	455	NUM
admet-3065	499	11	-	-	SYM
admet-3065	499	12	464	464	NUM
admet-3065	499	13	.	.	PUNCT
admet-3065	500	1	https://doi.org/10.1056/nejmra1706910	https://doi.org/10.1056/nejmra1706910	NOUN
admet-3065	501	1	[	[	X
admet-3065	501	2	26	26	NUM
admet-3065	501	3	]	]	PUNCT
admet-3065	501	4	a.	a.	NOUN
admet-3065	501	5	fire	fire	NOUN
admet-3065	501	6	,	,	PUNCT
admet-3065	501	7	s.	s.	PROPN
admet-3065	501	8	xu	xu	PROPN
admet-3065	501	9	,	,	PUNCT
admet-3065	501	10	m.k	m.k	PROPN
admet-3065	501	11	.	.	PROPN
admet-3065	501	12	montgomery	montgomery	PROPN
admet-3065	501	13	,	,	PUNCT
admet-3065	501	14	s.a	s.a	PROPN
admet-3065	501	15	.	.	PROPN
admet-3065	501	16	kostas	kostas	PROPN
admet-3065	501	17	,	,	PUNCT
admet-3065	501	18	s.e	s.e	PROPN
admet-3065	501	19	.	.	PROPN
admet-3065	501	20	driver	driver	PROPN
admet-3065	501	21	,	,	PUNCT
admet-3065	501	22	c.c	c.c	PROPN
admet-3065	501	23	.	.	PROPN
admet-3065	501	24	mello	mello	PROPN
admet-3065	501	25	.	.	PUNCT
admet-3065	502	1	potent	potent	NOUN
admet-3065	502	2	and	and	CCONJ
admet-3065	502	3	specific	specific	ADJ
admet-3065	502	4	genetic	genetic	ADJ
admet-3065	502	5	interference	interference	NOUN
admet-3065	502	6	by	by	ADP
admet-3065	502	7	double	double	ADJ
admet-3065	502	8	-	-	PUNCT
admet-3065	502	9	stranded	strand	VERB
admet-3065	502	10	rna	rna	NOUN
admet-3065	502	11	in	in	ADP
admet-3065	502	12	caenorhabditis	caenorhabditis	PROPN
admet-3065	502	13	elegans	elegans	PROPN
admet-3065	502	14	.	.	PUNCT
admet-3065	503	1	nature	nature	NOUN
admet-3065	503	2	391	391	NUM
admet-3065	503	3	(	(	PUNCT
admet-3065	503	4	1998	1998	NUM
admet-3065	503	5	)	)	PUNCT
admet-3065	503	6	806	806	NUM
admet-3065	503	7	-	-	SYM
admet-3065	503	8	811	811	NUM
admet-3065	503	9	.	.	PUNCT
admet-3065	504	1	https://doi.org/10.1038/35888	https://doi.org/10.1038/35888	PRON
admet-3065	505	1	[	[	X
admet-3065	505	2	27	27	NUM
admet-3065	505	3	]	]	X
admet-3065	505	4	c.e	c.e	PROPN
admet-3065	505	5	.	.	PROPN
admet-3065	505	6	thomas	thomas	PROPN
admet-3065	505	7	,	,	PUNCT
admet-3065	505	8	a.	a.	PROPN
admet-3065	505	9	ehrhardt	ehrhardt	PROPN
admet-3065	505	10	,	,	PUNCT
admet-3065	505	11	m.a	m.a	PROPN
admet-3065	505	12	.	.	PROPN
admet-3065	505	13	kay	kay	PROPN
admet-3065	505	14	.	.	PUNCT
admet-3065	506	1	progress	progress	NOUN
admet-3065	506	2	and	and	CCONJ
admet-3065	506	3	problems	problem	NOUN
admet-3065	506	4	with	with	ADP
admet-3065	506	5	the	the	DET
admet-3065	506	6	use	use	NOUN
admet-3065	506	7	of	of	ADP
admet-3065	506	8	viral	viral	ADJ
admet-3065	506	9	vectors	vector	NOUN
admet-3065	506	10	for	for	ADP
admet-3065	506	11	gene	gene	NOUN
admet-3065	506	12	therapy	therapy	NOUN
admet-3065	506	13	.	.	PUNCT
admet-3065	507	1	nature	nature	NOUN
admet-3065	507	2	reviews	review	VERB
admet-3065	507	3	genetics	genetic	NOUN
admet-3065	507	4	4	4	NUM
admet-3065	507	5	(	(	PUNCT
admet-3065	507	6	2003	2003	NUM
admet-3065	507	7	)	)	PUNCT
admet-3065	507	8	346	346	NUM
admet-3065	507	9	-	-	SYM
admet-3065	507	10	358	358	NUM
admet-3065	507	11	.	.	PUNCT
admet-3065	508	1	https://doi.org/10.1038/nrg1066	https://doi.org/10.1038/nrg1066	NOUN
admet-3065	509	1	[	[	X
admet-3065	509	2	28	28	NUM
admet-3065	509	3	]	]	PUNCT
admet-3065	509	4	m.	m.	NOUN
admet-3065	509	5	jinek	jinek	NOUN
admet-3065	509	6	,	,	PUNCT
admet-3065	509	7	k.	k.	PROPN
admet-3065	509	8	chylinski	chylinski	PROPN
admet-3065	509	9	,	,	PUNCT
admet-3065	509	10	i.	i.	PROPN
admet-3065	509	11	fonfara	fonfara	PROPN
admet-3065	509	12	,	,	PUNCT
admet-3065	509	13	m.	m.	PROPN
admet-3065	509	14	hauer	hauer	PROPN
admet-3065	509	15	,	,	PUNCT
admet-3065	509	16	j.a	j.a	PROPN
admet-3065	509	17	.	.	PROPN
admet-3065	509	18	doudna	doudna	PROPN
admet-3065	509	19	,	,	PUNCT
admet-3065	509	20	e.	e.	PROPN
admet-3065	509	21	charpentier	charpentier	PROPN
admet-3065	509	22	.	.	PUNCT
admet-3065	510	1	a	a	DET
admet-3065	510	2	programmable	programmable	ADJ
admet-3065	510	3	dual	dual	ADV
admet-3065	510	4	-	-	PUNCT
admet-3065	510	5	rnaguided	rnaguide	VERB
admet-3065	510	6	dna	dna	NOUN
admet-3065	510	7	endonuclease	endonuclease	NOUN
admet-3065	510	8	in	in	ADP
admet-3065	510	9	adaptive	adaptive	ADJ
admet-3065	510	10	bacterial	bacterial	ADJ
admet-3065	510	11	immunity	immunity	NOUN
admet-3065	510	12	.	.	PUNCT
admet-3065	511	1	science	science	NOUN
admet-3065	511	2	337	337	NUM
admet-3065	511	3	(	(	PUNCT
admet-3065	511	4	2012	2012	NUM
admet-3065	511	5	)	)	PUNCT
admet-3065	511	6	816	816	NUM
admet-3065	511	7	-	-	SYM
admet-3065	511	8	821	821	NUM
admet-3065	511	9	.	.	PUNCT
admet-3065	511	10	https://doi.org/10.1126/science.1225829	https://doi.org/10.1126/science.1225829	NOUN
admet-3065	512	1	[	[	X
admet-3065	512	2	29	29	NUM
admet-3065	512	3	]	]	X
admet-3065	512	4	h.	h.	PROPN
admet-3065	512	5	lv	lv	PROPN
admet-3065	512	6	,	,	PUNCT
admet-3065	512	7	s.	s.	PROPN
admet-3065	512	8	zhang	zhang	PROPN
admet-3065	512	9	,	,	PUNCT
admet-3065	512	10	b.	b.	PROPN
admet-3065	512	11	wang	wang	PROPN
admet-3065	512	12	,	,	PUNCT
admet-3065	512	13	s.	s.	PROPN
admet-3065	512	14	cui	cui	PROPN
admet-3065	512	15	,	,	PUNCT
admet-3065	512	16	j.	j.	PROPN
admet-3065	512	17	yan	yan	PROPN
admet-3065	512	18	.	.	PUNCT
admet-3065	512	19	toxicity	toxicity	NOUN
admet-3065	512	20	of	of	ADP
admet-3065	512	21	cationic	cationic	ADJ
admet-3065	512	22	lipids	lipid	NOUN
admet-3065	512	23	and	and	CCONJ
admet-3065	512	24	cationic	cationic	ADJ
admet-3065	512	25	polymers	polymer	NOUN
admet-3065	512	26	in	in	ADP
admet-3065	512	27	gene	gene	NOUN
admet-3065	512	28	delivery	delivery	NOUN
admet-3065	512	29	.	.	PUNCT
admet-3065	513	1	journal	journal	PROPN
admet-3065	513	2	of	of	ADP
admet-3065	513	3	controlled	control	VERB
admet-3065	513	4	release	release	NOUN
admet-3065	513	5	114	114	NUM
admet-3065	513	6	(	(	PUNCT
admet-3065	513	7	2006	2006	NUM
admet-3065	513	8	)	)	PUNCT
admet-3065	513	9	100	100	NUM
admet-3065	513	10	-	-	SYM
admet-3065	513	11	109	109	NUM
admet-3065	513	12	.	.	PUNCT
admet-3065	514	1	https://doi.org/10.1016/j.jconrel.2006.04.014	https://doi.org/10.1016/j.jconrel.2006.04.014	PROPN
admet-3065	515	1	[	[	X
admet-3065	515	2	30	30	NUM
admet-3065	515	3	]	]	X
admet-3065	515	4	d.w	d.w	PROPN
admet-3065	515	5	.	.	PROPN
admet-3065	515	6	pack	pack	PROPN
admet-3065	515	7	,	,	PUNCT
admet-3065	515	8	a.s	a.s	PROPN
admet-3065	515	9	.	.	PROPN
admet-3065	515	10	hoffman	hoffman	PROPN
admet-3065	515	11	,	,	PUNCT
admet-3065	515	12	s.	s.	PROPN
admet-3065	515	13	pun	pun	PROPN
admet-3065	515	14	,	,	PUNCT
admet-3065	515	15	p.s	p.s	PROPN
admet-3065	515	16	.	.	PROPN
admet-3065	515	17	stayton	stayton	PROPN
admet-3065	515	18	.	.	PUNCT
admet-3065	516	1	design	design	NOUN
admet-3065	516	2	and	and	CCONJ
admet-3065	516	3	development	development	NOUN
admet-3065	516	4	of	of	ADP
admet-3065	516	5	polymers	polymer	NOUN
admet-3065	516	6	for	for	ADP
admet-3065	516	7	gene	gene	NOUN
admet-3065	516	8	delivery	delivery	NOUN
admet-3065	516	9	.	.	PUNCT
admet-3065	517	1	nature	nature	NOUN
admet-3065	517	2	reviews	review	VERB
admet-3065	517	3	drug	drug	NOUN
admet-3065	517	4	discovery	discovery	NOUN
admet-3065	517	5	4	4	NUM
admet-3065	517	6	(	(	PUNCT
admet-3065	517	7	2005	2005	NUM
admet-3065	517	8	)	)	PUNCT
admet-3065	517	9	581	581	NUM
admet-3065	517	10	-	-	SYM
admet-3065	517	11	593	593	NUM
admet-3065	517	12	.	.	PUNCT
admet-3065	518	1	https://doi.org/10.1038/nrd1775	https://doi.org/10.1038/nrd1775	PRON
admet-3065	518	2	[	[	X
admet-3065	518	3	31	31	NUM
admet-3065	518	4	]	]	X
admet-3065	518	5	m.a	m.a	PROPN
admet-3065	518	6	.	.	PROPN
admet-3065	518	7	mintzer	mintzer	PROPN
admet-3065	518	8	,	,	PUNCT
admet-3065	518	9	e.e	e.e	PROPN
admet-3065	518	10	.	.	PROPN
admet-3065	518	11	simanek	simanek	PROPN
admet-3065	518	12	.	.	PUNCT
admet-3065	519	1	nonviral	nonviral	ADJ
admet-3065	519	2	vectors	vector	NOUN
admet-3065	519	3	for	for	ADP
admet-3065	519	4	gene	gene	NOUN
admet-3065	519	5	delivery	delivery	NOUN
admet-3065	519	6	.	.	PUNCT
admet-3065	520	1	chemical	chemical	ADJ
admet-3065	520	2	reviews	review	NOUN
admet-3065	520	3	109	109	NUM
admet-3065	520	4	(	(	PUNCT
admet-3065	520	5	2009	2009	NUM
admet-3065	520	6	)	)	PUNCT
admet-3065	520	7	259302	259302	NUM
admet-3065	520	8	.	.	PUNCT
admet-3065	521	1	https://doi.org/10.1021/cr800409e	https://doi.org/10.1021/cr800409e	X
admet-3065	522	1	[	[	X
admet-3065	522	2	32	32	NUM
admet-3065	522	3	]	]	SYM
admet-3065	522	4	c.m	c.m	PROPN
admet-3065	522	5	.	.	PROPN
admet-3065	522	6	wiethoff	wiethoff	PROPN
admet-3065	522	7	,	,	PUNCT
admet-3065	522	8	c.r	c.r	PROPN
admet-3065	522	9	.	.	PROPN
admet-3065	522	10	middaugh	middaugh	PROPN
admet-3065	522	11	.	.	PUNCT
admet-3065	523	1	barriers	barrier	NOUN
admet-3065	523	2	to	to	ADP
admet-3065	523	3	nonviral	nonviral	ADJ
admet-3065	523	4	gene	gene	NOUN
admet-3065	523	5	delivery	delivery	NOUN
admet-3065	523	6	.	.	PUNCT
admet-3065	524	1	journal	journal	NOUN
admet-3065	524	2	of	of	ADP
admet-3065	524	3	pharmaceutical	pharmaceutical	PROPN
admet-3065	524	4	sciences	science	NOUN
admet-3065	524	5	92	92	NUM
admet-3065	524	6	(	(	PUNCT
admet-3065	524	7	2003	2003	NUM
admet-3065	524	8	)	)	PUNCT
admet-3065	524	9	203	203	NUM
admet-3065	524	10	-	-	SYM
admet-3065	524	11	217	217	NUM
admet-3065	524	12	.	.	PUNCT
admet-3065	525	1	https://doi.org/10.1002/jps.10286	https://doi.org/10.1002/jps.10286	ADJ
admet-3065	525	2	[	[	X
admet-3065	525	3	33	33	NUM
admet-3065	525	4	]	]	X
admet-3065	525	5	s.d	s.d	PROPN
admet-3065	525	6	.	.	PROPN
admet-3065	525	7	conner	conner	PROPN
admet-3065	525	8	,	,	PUNCT
admet-3065	525	9	s.l	s.l	PROPN
admet-3065	525	10	.	.	PROPN
admet-3065	525	11	schmid	schmid	PROPN
admet-3065	525	12	.	.	PUNCT
admet-3065	526	1	regulated	regulate	VERB
admet-3065	526	2	portals	portal	NOUN
admet-3065	526	3	of	of	ADP
admet-3065	526	4	entry	entry	NOUN
admet-3065	526	5	into	into	ADP
admet-3065	526	6	the	the	DET
admet-3065	526	7	cell	cell	NOUN
admet-3065	526	8	.	.	PUNCT
admet-3065	527	1	nature	nature	NOUN
admet-3065	527	2	422	422	NUM
admet-3065	527	3	(	(	PUNCT
admet-3065	527	4	2003	2003	NUM
admet-3065	527	5	)	)	PUNCT
admet-3065	527	6	37	37	NUM
admet-3065	527	7	-	-	SYM
admet-3065	527	8	44	44	NUM
admet-3065	527	9	.	.	PUNCT
admet-3065	528	1	https://doi.org/10.1038/nature01451	https://doi.org/10.1038/nature01451	PROPN
admet-3065	529	1	[	[	X
admet-3065	529	2	34	34	NUM
admet-3065	529	3	]	]	X
admet-3065	529	4	g.j	g.j	PROPN
admet-3065	529	5	.	.	PROPN
admet-3065	529	6	doherty	doherty	PROPN
admet-3065	529	7	,	,	PUNCT
admet-3065	529	8	h.t	h.t	PROPN
admet-3065	529	9	.	.	PROPN
admet-3065	529	10	mcmahon	mcmahon	PROPN
admet-3065	529	11	.	.	PUNCT
admet-3065	529	12	mechanisms	mechanism	NOUN
admet-3065	529	13	of	of	ADP
admet-3065	529	14	endocytosis	endocytosis	NOUN
admet-3065	529	15	.	.	PUNCT
admet-3065	530	1	annual	annual	ADJ
admet-3065	530	2	review	review	NOUN
admet-3065	530	3	of	of	ADP
admet-3065	530	4	biochemistry	biochemistry	NOUN
admet-3065	530	5	78	78	NUM
admet-3065	530	6	(	(	PUNCT
admet-3065	530	7	2009	2009	NUM
admet-3065	530	8	)	)	PUNCT
admet-3065	530	9	857	857	NUM
admet-3065	530	10	-	-	SYM
admet-3065	530	11	902	902	NUM
admet-3065	530	12	.	.	PUNCT
admet-3065	531	1	https://doi.org/10.1146/annurev.biochem.78.081307.110540	https://doi.org/10.1146/annurev.biochem.78.081307.110540	PUNCT
admet-3065	532	1	[	[	X
admet-3065	532	2	35	35	NUM
admet-3065	532	3	]	]	PUNCT
admet-3065	532	4	j.	j.	PROPN
admet-3065	532	5	huotari	huotari	PROPN
admet-3065	532	6	,	,	PUNCT
admet-3065	532	7	a.	a.	PROPN
admet-3065	532	8	helenius	helenius	PROPN
admet-3065	532	9	.	.	PUNCT
admet-3065	533	1	endosome	endosome	PROPN
admet-3065	533	2	maturation	maturation	PROPN
admet-3065	533	3	.	.	PUNCT
admet-3065	534	1	the	the	DET
admet-3065	534	2	embo	embo	PROPN
admet-3065	534	3	journal	journal	PROPN
admet-3065	534	4	30	30	NUM
admet-3065	534	5	(	(	PUNCT
admet-3065	534	6	2011	2011	NUM
admet-3065	534	7	)	)	PUNCT
admet-3065	534	8	3481	3481	NUM
admet-3065	534	9	-	-	SYM
admet-3065	534	10	3500	3500	NUM
admet-3065	534	11	.	.	PUNCT
admet-3065	535	1	https://doi.org/10.1038/emboj.2011.286	https://doi.org/10.1038/emboj.2011.286	ADJ
admet-3065	535	2	[	[	X
admet-3065	535	3	36	36	NUM
admet-3065	535	4	]	]	X
admet-3065	535	5	d.a	d.a	PROPN
admet-3065	535	6	.	.	PROPN
admet-3065	535	7	dean	dean	PROPN
admet-3065	535	8	,	,	PUNCT
admet-3065	535	9	d.d	d.d	PROPN
admet-3065	535	10	.	.	PROPN
admet-3065	535	11	strong	strong	PROPN
admet-3065	535	12	,	,	PUNCT
admet-3065	536	1	w.e	w.e	PROPN
admet-3065	536	2	.	.	PROPN
admet-3065	536	3	zimmer	zimmer	PROPN
admet-3065	536	4	.	.	PUNCT
admet-3065	536	5	nuclear	nuclear	ADJ
admet-3065	536	6	entry	entry	NOUN
admet-3065	536	7	of	of	ADP
admet-3065	536	8	nonviral	nonviral	ADJ
admet-3065	536	9	vectors	vector	NOUN
admet-3065	536	10	.	.	PUNCT
admet-3065	537	1	gene	gene	NOUN
admet-3065	537	2	therapy	therapy	NOUN
admet-3065	537	3	12	12	NUM
admet-3065	537	4	(	(	PUNCT
admet-3065	537	5	2005	2005	NUM
admet-3065	537	6	)	)	PUNCT
admet-3065	537	7	881	881	NUM
admet-3065	537	8	-	-	SYM
admet-3065	537	9	890	890	NUM
admet-3065	537	10	.	.	PUNCT
admet-3065	538	1	https://doi.org/10.1038/sj.gt.3302534	https://doi.org/10.1038/sj.gt.3302534	NOUN
admet-3065	538	2	[	[	X
admet-3065	538	3	37	37	NUM
admet-3065	538	4	]	]	X
admet-3065	538	5	m.l	m.l	PROPN
admet-3065	538	6	.	.	PROPN
admet-3065	538	7	read	read	PROPN
admet-3065	538	8	,	,	PUNCT
admet-3065	539	1	k.h	k.h	PROPN
admet-3065	539	2	.	.	PROPN
admet-3065	539	3	bremner	bremner	PROPN
admet-3065	539	4	,	,	PUNCT
admet-3065	539	5	d.	d.	PROPN
admet-3065	539	6	oupický	oupický	PROPN
admet-3065	539	7	,	,	PUNCT
admet-3065	539	8	n.k	n.k	PROPN
admet-3065	539	9	.	.	NOUN
admet-3065	539	10	green	green	PROPN
admet-3065	539	11	,	,	PUNCT
admet-3065	539	12	p.f	p.f	PROPN
admet-3065	539	13	.	.	PROPN
admet-3065	539	14	searle	searle	PROPN
admet-3065	539	15	,	,	PUNCT
admet-3065	539	16	l.w	l.w	PROPN
admet-3065	539	17	.	.	PROPN
admet-3065	539	18	seymour	seymour	PROPN
admet-3065	539	19	.	.	PUNCT
admet-3065	540	1	vectors	vector	NOUN
admet-3065	540	2	based	base	VERB
admet-3065	540	3	on	on	ADP
admet-3065	540	4	reducible	reducible	ADJ
admet-3065	540	5	polycations	polycation	NOUN
admet-3065	540	6	facilitate	facilitate	VERB
admet-3065	540	7	intracellular	intracellular	ADJ
admet-3065	540	8	release	release	NOUN
admet-3065	540	9	of	of	ADP
admet-3065	540	10	nucleic	nucleic	ADJ
admet-3065	540	11	acids	acid	NOUN
admet-3065	540	12	.	.	PUNCT
admet-3065	541	1	the	the	DET
admet-3065	541	2	journal	journal	NOUN
admet-3065	541	3	of	of	ADP
admet-3065	541	4	gene	gene	NOUN
admet-3065	541	5	medicine	medicine	NOUN
admet-3065	541	6	5	5	NUM
admet-3065	541	7	(	(	PUNCT
admet-3065	541	8	2003	2003	NUM
admet-3065	541	9	)	)	PUNCT
admet-3065	541	10	232	232	NUM
admet-3065	541	11	-	-	SYM
admet-3065	541	12	241	241	NUM
admet-3065	541	13	.	.	PUNCT
admet-3065	542	1	https://doi.org/10.1002/jgm.331	https://doi.org/10.1002/jgm.331	PROPN
admet-3065	543	1	[	[	X
admet-3065	543	2	38	38	NUM
admet-3065	543	3	]	]	PUNCT
admet-3065	543	4	s.	s.	PROPN
admet-3065	543	5	simões	simões	PROPN
admet-3065	543	6	,	,	PUNCT
admet-3065	543	7	v.	v.	ADP
admet-3065	543	8	slepushkin	slepushkin	PROPN
admet-3065	543	9	,	,	PUNCT
admet-3065	543	10	n.	n.	PROPN
admet-3065	543	11	düzgünes	düzgünes	PROPN
admet-3065	543	12	,	,	PUNCT
admet-3065	543	13	m.c	m.c	PROPN
admet-3065	543	14	.	.	PROPN
admet-3065	543	15	pedroso	pedroso	PROPN
admet-3065	543	16	de	de	X
admet-3065	543	17	lima	lima	PROPN
admet-3065	543	18	.	.	PUNCT
admet-3065	544	1	on	on	ADP
admet-3065	544	2	the	the	DET
admet-3065	544	3	mechanisms	mechanism	NOUN
admet-3065	544	4	of	of	ADP
admet-3065	544	5	internalization	internalization	NOUN
admet-3065	544	6	and	and	CCONJ
admet-3065	544	7	intracellular	intracellular	ADJ
admet-3065	544	8	delivery	delivery	NOUN
admet-3065	544	9	mediated	mediate	VERB
admet-3065	544	10	by	by	ADP
admet-3065	544	11	cationic	cationic	ADJ
admet-3065	544	12	liposomes	liposome	NOUN
admet-3065	544	13	.	.	PUNCT
admet-3065	545	1	biochimica	biochimica	PROPN
admet-3065	545	2	et	et	PROPN
admet-3065	545	3	biophysica	biophysica	PROPN
admet-3065	545	4	acta	acta	PROPN
admet-3065	545	5	1515	1515	NUM
admet-3065	545	6	(	(	PUNCT
admet-3065	545	7	2001	2001	NUM
admet-3065	545	8	)	)	PUNCT
admet-3065	545	9	23	23	NUM
admet-3065	545	10	-	-	SYM
admet-3065	545	11	37	37	NUM
admet-3065	545	12	.	.	PUNCT
admet-3065	546	1	https://doi.org/10.1016/s0005-2736(01)00389-3	https://doi.org/10.1016/s0005-2736(01)00389-3	VERB
admet-3065	547	1	[	[	X
admet-3065	547	2	39	39	NUM
admet-3065	547	3	]	]	X
admet-3065	547	4	j.p	j.p	PROPN
admet-3065	547	5	.	.	PROPN
admet-3065	547	6	behr	behr	PROPN
admet-3065	547	7	,	,	PUNCT
admet-3065	547	8	b.	b.	PROPN
admet-3065	547	9	demeneix	demeneix	PROPN
admet-3065	547	10	,	,	PUNCT
admet-3065	547	11	j.p	j.p	PROPN
admet-3065	547	12	.	.	PROPN
admet-3065	547	13	loeffler	loeffler	PROPN
admet-3065	547	14	,	,	PUNCT
admet-3065	547	15	j.	j.	PROPN
admet-3065	547	16	perez	perez	PROPN
admet-3065	547	17	-	-	PUNCT
admet-3065	547	18	mutul	mutul	NOUN
admet-3065	547	19	.	.	PUNCT
admet-3065	548	1	efficient	efficient	ADJ
admet-3065	548	2	gene	gene	NOUN
admet-3065	548	3	transfer	transfer	NOUN
admet-3065	548	4	into	into	ADP
admet-3065	548	5	mammalian	mammalian	ADJ
admet-3065	548	6	primary	primary	ADJ
admet-3065	548	7	endocrine	endocrine	NOUN
admet-3065	548	8	cells	cell	NOUN
admet-3065	548	9	with	with	ADP
admet-3065	548	10	lipopolyamine	lipopolyamine	NOUN
admet-3065	548	11	-	-	PUNCT
admet-3065	548	12	coated	coat	VERB
admet-3065	548	13	dna	dna	NOUN
admet-3065	548	14	.	.	PUNCT
admet-3065	549	1	proceedings	proceeding	NOUN
admet-3065	549	2	of	of	ADP
admet-3065	549	3	the	the	DET
admet-3065	549	4	national	national	PROPN
admet-3065	549	5	academy	academy	PROPN
admet-3065	549	6	of	of	ADP
admet-3065	549	7	sciences	sciences	PROPN
admet-3065	549	8	86	86	NUM
admet-3065	549	9	(	(	PUNCT
admet-3065	549	10	1989	1989	NUM
admet-3065	549	11	)	)	PUNCT
admet-3065	549	12	6982	6982	NUM
admet-3065	549	13	-	-	SYM
admet-3065	549	14	6986	6986	NUM
admet-3065	549	15	.	.	PUNCT
admet-3065	550	1	https://doi.org/10.1073/pnas.86.18.6982	https://doi.org/10.1073/pnas.86.18.6982	PROPN
admet-3065	551	1	[	[	X
admet-3065	551	2	40	40	NUM
admet-3065	551	3	]	]	X
admet-3065	551	4	e.s	e.s	PROPN
admet-3065	551	5	.	.	PROPN
admet-3065	551	6	yang	yang	PROPN
admet-3065	551	7	,	,	PUNCT
admet-3065	551	8	s.	s.	PROPN
admet-3065	551	9	may	may	AUX
admet-3065	551	10	.	.	PUNCT
admet-3065	552	1	release	release	NOUN
admet-3065	552	2	of	of	ADP
admet-3065	552	3	cationic	cationic	ADJ
admet-3065	552	4	polymer	polymer	NOUN
admet-3065	552	5	-	-	PUNCT
admet-3065	552	6	dna	dna	NOUN
admet-3065	552	7	complexes	complex	NOUN
admet-3065	552	8	from	from	ADP
admet-3065	552	9	the	the	DET
admet-3065	552	10	endosome	endosome	NOUN
admet-3065	552	11	:	:	PUNCT
admet-3065	552	12	a	a	DET
admet-3065	552	13	theoretical	theoretical	ADJ
admet-3065	552	14	investigation	investigation	NOUN
admet-3065	552	15	of	of	ADP
admet-3065	552	16	the	the	DET
admet-3065	552	17	proton	proton	NOUN
admet-3065	552	18	sponge	sponge	NOUN
admet-3065	552	19	hypothesis	hypothesis	NOUN
admet-3065	552	20	.	.	PUNCT
admet-3065	553	1	the	the	DET
admet-3065	553	2	journal	journal	PROPN
admet-3065	553	3	of	of	ADP
admet-3065	553	4	chemical	chemical	PROPN
admet-3065	553	5	physics	physics	PROPN
admet-3065	553	6	129	129	NUM
admet-3065	553	7	(	(	PUNCT
admet-3065	553	8	2008	2008	NUM
admet-3065	553	9	)	)	PUNCT
admet-3065	553	10	185105	185105	NUM
admet-3065	553	11	.	.	PUNCT
admet-3065	554	1	https://doi.org/10.1063/1.3009263	https://doi.org/10.1063/1.3009263	PROPN
admet-3065	555	1	[	[	X
admet-3065	555	2	41	41	NUM
admet-3065	555	3	]	]	PUNCT
admet-3065	555	4	k.	k.	PROPN
admet-3065	555	5	shi	shi	PROPN
admet-3065	555	6	,	,	PUNCT
admet-3065	555	7	j.	j.	PROPN
admet-3065	555	8	li	li	PROPN
admet-3065	555	9	,	,	PUNCT
admet-3065	555	10	z.	z.	PROPN
admet-3065	555	11	cao	cao	PROPN
admet-3065	555	12	,	,	PUNCT
admet-3065	555	13	p.	p.	PROPN
admet-3065	555	14	yang	yang	PROPN
admet-3065	555	15	,	,	PUNCT
admet-3065	555	16	y.	y.	PROPN
admet-3065	555	17	qiu	qiu	PROPN
admet-3065	555	18	,	,	PUNCT
admet-3065	555	19	b.	b.	PROPN
admet-3065	555	20	yang	yang	PROPN
admet-3065	555	21	,	,	PUNCT
admet-3065	555	22	y.	y.	PROPN
admet-3065	555	23	wang	wang	PROPN
admet-3065	555	24	,	,	PUNCT
admet-3065	555	25	y.	y.	PROPN
admet-3065	555	26	long	long	PROPN
admet-3065	555	27	,	,	PUNCT
admet-3065	555	28	y.	y.	PROPN
admet-3065	555	29	liu	liu	PROPN
admet-3065	555	30	,	,	PUNCT
admet-3065	555	31	q.	q.	PROPN
admet-3065	555	32	zhang	zhang	PROPN
admet-3065	555	33	,	,	PUNCT
admet-3065	555	34	j.	j.	PROPN
admet-3065	555	35	qian	qian	PROPN
admet-3065	555	36	,	,	PUNCT
admet-3065	555	37	z.	z.	PROPN
admet-3065	555	38	zhang	zhang	PROPN
admet-3065	555	39	,	,	PUNCT
admet-3065	555	40	h.	h.	PROPN
admet-3065	555	41	gao	gao	PROPN
admet-3065	555	42	and	and	CCONJ
admet-3065	555	43	q.	q.	PROPN
admet-3065	555	44	he	he	PRON
admet-3065	555	45	.	.	PUNCT
admet-3065	556	1	a	a	DET
admet-3065	556	2	ph	ph	VERB
admet-3065	556	3	-	-	PUNCT
admet-3065	556	4	responsive	responsive	ADJ
admet-3065	556	5	cell	cell	NOUN
admet-3065	556	6	-	-	PUNCT
admet-3065	556	7	penetrating	penetrate	VERB
admet-3065	556	8	peptide	peptide	NOUN
admet-3065	556	9	-	-	PUNCT
admet-3065	556	10	modified	modify	VERB
admet-3065	556	11	liposomes	liposome	NOUN
admet-3065	556	12	with	with	ADP
admet-3065	556	13	active	active	ADJ
admet-3065	556	14	recognizing	recognizing	NOUN
admet-3065	556	15	of	of	ADP
admet-3065	556	16	integrin	integrin	NOUN
admet-3065	556	17	αvβ3	αvβ3	NOUN
admet-3065	556	18	for	for	ADP
admet-3065	556	19	the	the	DET
admet-3065	556	20	treatment	treatment	NOUN
admet-3065	556	21	of	of	ADP
admet-3065	556	22	melanoma	melanoma	NOUN
admet-3065	556	23	.	.	PUNCT
admet-3065	557	1	control	control	NOUN
admet-3065	557	2	release	release	NOUN
admet-3065	557	3	217	217	NUM
admet-3065	557	4	(	(	PUNCT
admet-3065	557	5	2015	2015	NUM
admet-3065	557	6	)	)	PUNCT
admet-3065	557	7	138	138	NUM
admet-3065	557	8	-	-	SYM
admet-3065	557	9	150	150	NUM
admet-3065	557	10	.	.	PUNCT
admet-3065	558	1	https://doi.org/10.1016/j.jconrel.2015.09.009	https://doi.org/10.1016/j.jconrel.2015.09.009	PROPN
admet-3065	558	2	https://doi.org/10.1038/sj.gt.3302925	https://doi.org/10.1038/sj.gt.3302925	NOUN
admet-3065	558	3	.	.	PUNCT
admet-3065	559	1	https://doi.org/10.1126/science.175.4025.949	https://doi.org/10.1126/science.175.4025.949	PROPN
admet-3065	559	2	https://doi.org/10.1016/j.lfs.2022.120375	https://doi.org/10.1016/j.lfs.2022.120375	PROPN
admet-3065	559	3	.	.	PUNCT
admet-3065	559	4	https://doi.org/10.1056/nejmra1706910	https://doi.org/10.1056/nejmra1706910	NOUN
admet-3065	559	5	.	.	PUNCT
admet-3065	560	1	https://doi.org/10.1038/35888	https://doi.org/10.1038/35888	NOUN
admet-3065	560	2	.	.	PUNCT
admet-3065	560	3	https://doi.org/10.1038/nrg1066	https://doi.org/10.1038/nrg1066	PROPN
admet-3065	560	4	.	.	PUNCT
admet-3065	560	5	https://doi.org/10.1126/science.1225829	https://doi.org/10.1126/science.1225829	PROPN
admet-3065	560	6	https://doi.org/10.1016/j.jconrel.2006.04.014	https://doi.org/10.1016/j.jconrel.2006.04.014	PROPN
admet-3065	560	7	.	.	PUNCT
admet-3065	561	1	https://doi.org/10.1038/nrd1775	https://doi.org/10.1038/nrd1775	PROPN
admet-3065	561	2	.	.	PUNCT
admet-3065	562	1	https://doi.org/10.1021/cr800409e	https://doi.org/10.1021/cr800409e	PROPN
admet-3065	562	2	.	.	PUNCT
admet-3065	563	1	https://doi.org/10.1002/jps.10286	https://doi.org/10.1002/jps.10286	PROPN
admet-3065	563	2	.	.	PUNCT
admet-3065	564	1	https://doi.org/10.1038/nature01451	https://doi.org/10.1038/nature01451	PROPN
admet-3065	564	2	.	.	PUNCT
admet-3065	565	1	https://doi.org/10.1146/annurev.biochem.78.081307.110540	https://doi.org/10.1146/annurev.biochem.78.081307.110540	PROPN
admet-3065	565	2	.	.	PUNCT
admet-3065	566	1	https://doi.org/10.1038/emboj.2011.286	https://doi.org/10.1038/emboj.2011.286	PROPN
admet-3065	566	2	.	.	PUNCT
admet-3065	567	1	https://doi.org/10.1038/sj.gt.3302534	https://doi.org/10.1038/sj.gt.3302534	NOUN
admet-3065	567	2	.	.	PUNCT
admet-3065	568	1	https://doi.org/10.1002/jgm.331	https://doi.org/10.1002/jgm.331	PROPN
admet-3065	568	2	.	.	PROPN
admet-3065	569	1	https://doi.org/10.1016/s0005-2736(01)00389-3	https://doi.org/10.1016/s0005-2736(01)00389-3	PROPN
admet-3065	569	2	https://doi.org/10.1073/pnas.86.18.6982	https://doi.org/10.1073/pnas.86.18.6982	PROPN
admet-3065	569	3	.	.	PUNCT
admet-3065	570	1	https://doi.org/10.1063/1.3009263	https://doi.org/10.1063/1.3009263	PROPN
admet-3065	570	2	https://doi.org/10.1016/j.jconrel.2015.09.009	https://doi.org/10.1016/j.jconrel.2015.09.009	PROPN
admet-3065	570	3	admet	admet	PROPN
admet-3065	570	4	&	&	CCONJ
admet-3065	570	5	dmpk	dmpk	PROPN
admet-3065	570	6	00(0	00(0	PROPN
admet-3065	570	7	)	)	PUNCT
admet-3065	570	8	(	(	PUNCT
admet-3065	570	9	2025	2025	NUM
admet-3065	570	10	)	)	PUNCT
admet-3065	570	11	3065	3065	NUM
admet-3065	570	12	liposome	liposome	NOUN
admet-3065	570	13	-	-	PUNCT
admet-3065	570	14	mediated	mediate	VERB
admet-3065	570	15	gene	gene	NOUN
admet-3065	570	16	delivery	delivery	NOUN
admet-3065	570	17	doi	doi	NOUN
admet-3065	570	18	:	:	PUNCT
admet-3065	570	19	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	570	20	21	21	NUM
admet-3065	571	1	[	[	X
admet-3065	571	2	42	42	NUM
admet-3065	571	3	]	]	X
admet-3065	571	4	n.	n.	PROPN
admet-3065	571	5	sayed	say	VERB
admet-3065	571	6	,	,	PUNCT
admet-3065	571	7	p.	p.	NOUN
admet-3065	571	8	allawadhi	allawadhi	PROPN
admet-3065	571	9	,	,	PUNCT
admet-3065	571	10	a.	a.	NOUN
admet-3065	571	11	khurana	khurana	PROPN
admet-3065	571	12	,	,	PUNCT
admet-3065	571	13	v.	v.	ADP
admet-3065	571	14	singh	singh	PROPN
admet-3065	571	15	,	,	PUNCT
admet-3065	571	16	u.	u.	PROPN
admet-3065	571	17	navik	navik	PROPN
admet-3065	571	18	,	,	PUNCT
admet-3065	571	19	s.k	s.k	PROPN
admet-3065	571	20	.	.	PROPN
admet-3065	571	21	pasumarthi	pasumarthi	PROPN
admet-3065	571	22	,	,	PUNCT
admet-3065	571	23	i.	i.	PROPN
admet-3065	571	24	khurana	khurana	PROPN
admet-3065	571	25	,	,	PUNCT
admet-3065	571	26	a.k	a.k	PROPN
admet-3065	571	27	.	.	PROPN
admet-3065	571	28	banothu	banothu	PROPN
admet-3065	571	29	,	,	PUNCT
admet-3065	571	30	r.	r.	PROPN
admet-3065	571	31	weiskirchen	weiskirchen	PROPN
admet-3065	571	32	,	,	PUNCT
admet-3065	571	33	k.k	k.k	PROPN
admet-3065	571	34	.	.	PROPN
admet-3065	571	35	bharani	bharani	PROPN
admet-3065	571	36	.	.	PUNCT
admet-3065	572	1	gene	gene	NOUN
admet-3065	572	2	therapy	therapy	NOUN
admet-3065	572	3	:	:	PUNCT
admet-3065	572	4	comprehensive	comprehensive	ADJ
admet-3065	572	5	overview	overview	NOUN
admet-3065	572	6	and	and	CCONJ
admet-3065	572	7	therapeutic	therapeutic	ADJ
admet-3065	572	8	applications	application	NOUN
admet-3065	572	9	.	.	PUNCT
admet-3065	573	1	life	life	NOUN
admet-3065	573	2	sciences	science	VERB
admet-3065	573	3	294	294	NUM
admet-3065	573	4	(	(	PUNCT
admet-3065	573	5	2022	2022	NUM
admet-3065	573	6	)	)	PUNCT
admet-3065	573	7	120375	120375	NUM
admet-3065	573	8	.	.	PUNCT
admet-3065	574	1	https://doi.org/10.1016/j.lfs.2022.120375	https://doi.org/10.1016/j.lfs.2022.120375	PUNCT
admet-3065	575	1	[	[	X
admet-3065	575	2	43	43	NUM
admet-3065	575	3	]	]	X
admet-3065	575	4	m.a	m.a	PROPN
admet-3065	575	5	.	.	PROPN
admet-3065	575	6	kay	kay	PROPN
admet-3065	575	7	,	,	PUNCT
admet-3065	575	8	j.c	j.c	PROPN
admet-3065	575	9	.	.	PROPN
admet-3065	575	10	glorioso	glorioso	PROPN
admet-3065	575	11	,	,	PUNCT
admet-3065	575	12	l.	l.	PROPN
admet-3065	575	13	naldini	naldini	PROPN
admet-3065	575	14	.	.	PUNCT
admet-3065	576	1	viral	viral	ADJ
admet-3065	576	2	vectors	vector	NOUN
admet-3065	576	3	for	for	ADP
admet-3065	576	4	gene	gene	NOUN
admet-3065	576	5	therapy	therapy	NOUN
admet-3065	576	6	:	:	PUNCT
admet-3065	576	7	the	the	DET
admet-3065	576	8	art	art	NOUN
admet-3065	576	9	of	of	ADP
admet-3065	576	10	turning	turn	VERB
admet-3065	576	11	infectious	infectious	ADJ
admet-3065	576	12	agents	agent	NOUN
admet-3065	576	13	into	into	ADP
admet-3065	576	14	vehicles	vehicle	NOUN
admet-3065	576	15	of	of	ADP
admet-3065	576	16	therapeutics	therapeutic	NOUN
admet-3065	576	17	.	.	PUNCT
admet-3065	577	1	nature	nature	NOUN
admet-3065	577	2	medicine	medicine	NOUN
admet-3065	577	3	7	7	NUM
admet-3065	577	4	(	(	PUNCT
admet-3065	577	5	2001	2001	NUM
admet-3065	577	6	)	)	PUNCT
admet-3065	577	7	33	33	NUM
admet-3065	577	8	-	-	SYM
admet-3065	577	9	40	40	NUM
admet-3065	577	10	.	.	PUNCT
admet-3065	578	1	https://doi.org/10.1038/83324	https://doi.org/10.1038/83324	PROPN
admet-3065	579	1	[	[	X
admet-3065	579	2	44	44	NUM
admet-3065	579	3	]	]	PUNCT
admet-3065	579	4	j.	j.	PROPN
admet-3065	579	5	gehl	gehl	PROPN
admet-3065	579	6	.	.	PUNCT
admet-3065	580	1	electroporation	electroporation	NOUN
admet-3065	580	2	:	:	PUNCT
admet-3065	580	3	theory	theory	NOUN
admet-3065	580	4	and	and	CCONJ
admet-3065	580	5	methods	method	NOUN
admet-3065	580	6	,	,	PUNCT
admet-3065	580	7	perspectives	perspective	NOUN
admet-3065	580	8	for	for	ADP
admet-3065	580	9	drug	drug	NOUN
admet-3065	580	10	delivery	delivery	NOUN
admet-3065	580	11	,	,	PUNCT
admet-3065	580	12	gene	gene	NOUN
admet-3065	580	13	therapy	therapy	NOUN
admet-3065	580	14	and	and	CCONJ
admet-3065	580	15	research	research	NOUN
admet-3065	580	16	.	.	PUNCT
admet-3065	581	1	acta	acta	PROPN
admet-3065	581	2	physiologica	physiologica	PROPN
admet-3065	581	3	scandinavica	scandinavica	PROPN
admet-3065	581	4	177	177	NUM
admet-3065	581	5	(	(	PUNCT
admet-3065	581	6	2003	2003	NUM
admet-3065	581	7	)	)	PUNCT
admet-3065	581	8	437	437	NUM
admet-3065	581	9	-	-	SYM
admet-3065	581	10	447	447	NUM
admet-3065	581	11	.	.	PUNCT
admet-3065	582	1	https://doi.org/10.1046/j.1365201x.2003.01093.x	https://doi.org/10.1046/j.1365201x.2003.01093.x	PRON
admet-3065	583	1	[	[	X
admet-3065	583	2	45	45	NUM
admet-3065	583	3	]	]	X
admet-3065	583	4	v.p	v.p	PROPN
admet-3065	583	5	.	.	PROPN
admet-3065	583	6	torchilin	torchilin	PROPN
admet-3065	583	7	.	.	PUNCT
admet-3065	584	1	recent	recent	ADJ
admet-3065	584	2	approaches	approach	NOUN
admet-3065	584	3	to	to	ADP
admet-3065	584	4	intracellular	intracellular	ADJ
admet-3065	584	5	delivery	delivery	NOUN
admet-3065	584	6	of	of	ADP
admet-3065	584	7	drugs	drug	NOUN
admet-3065	584	8	and	and	CCONJ
admet-3065	584	9	dna	dna	PROPN
admet-3065	584	10	and	and	CCONJ
admet-3065	584	11	organelle	organelle	PROPN
admet-3065	584	12	targeting	targeting	NOUN
admet-3065	584	13	.	.	PUNCT
admet-3065	585	1	annual	annual	ADJ
admet-3065	585	2	review	review	NOUN
admet-3065	585	3	of	of	ADP
admet-3065	585	4	biomedical	biomedical	ADJ
admet-3065	585	5	engineering	engineering	NOUN
admet-3065	585	6	8	8	NUM
admet-3065	585	7	(	(	PUNCT
admet-3065	585	8	2006	2006	NUM
admet-3065	585	9	)	)	PUNCT
admet-3065	585	10	343	343	NUM
admet-3065	585	11	-	-	SYM
admet-3065	585	12	375	375	NUM
admet-3065	585	13	.	.	PUNCT
admet-3065	586	1	https://doi.org/10.1016/j.addr.2006.09.009	https://doi.org/10.1016/j.addr.2006.09.009	PROPN
admet-3065	586	2	[	[	X
admet-3065	586	3	46	46	NUM
admet-3065	586	4	]	]	X
admet-3065	586	5	a.d	a.d	PROPN
admet-3065	586	6	.	.	PROPN
admet-3065	586	7	bangham	bangham	PROPN
admet-3065	586	8	,	,	PUNCT
admet-3065	586	9	r.w	r.w	PROPN
admet-3065	586	10	.	.	PROPN
admet-3065	586	11	horne	horne	PROPN
admet-3065	586	12	.	.	PUNCT
admet-3065	587	1	negative	negative	ADJ
admet-3065	587	2	staining	staining	NOUN
admet-3065	587	3	of	of	ADP
admet-3065	587	4	phospholipids	phospholipid	NOUN
admet-3065	587	5	and	and	CCONJ
admet-3065	587	6	their	their	PRON
admet-3065	587	7	structural	structural	ADJ
admet-3065	587	8	modification	modification	NOUN
admet-3065	587	9	by	by	ADP
admet-3065	587	10	surface	surface	NOUN
admet-3065	587	11	-	-	PUNCT
admet-3065	587	12	active	active	ADJ
admet-3065	587	13	agents	agent	NOUN
admet-3065	587	14	as	as	SCONJ
admet-3065	587	15	observed	observe	VERB
admet-3065	587	16	in	in	ADP
admet-3065	587	17	the	the	DET
admet-3065	587	18	electron	electron	NOUN
admet-3065	587	19	microscope	microscope	NOUN
admet-3065	587	20	.	.	PUNCT
admet-3065	588	1	journal	journal	NOUN
admet-3065	588	2	of	of	ADP
admet-3065	588	3	molecular	molecular	ADJ
admet-3065	588	4	biology	biology	NOUN
admet-3065	588	5	8	8	NUM
admet-3065	588	6	(	(	PUNCT
admet-3065	588	7	1964	1964	NUM
admet-3065	588	8	)	)	PUNCT
admet-3065	588	9	660	660	NUM
admet-3065	588	10	-	-	NUM
admet-3065	588	11	668	668	NUM
admet-3065	588	12	.	.	PUNCT
admet-3065	589	1	https://doi.org/10.1016/s0022-2836(64)80115-7	https://doi.org/10.1016/s0022-2836(64)80115-7	NOUN
admet-3065	589	2	[	[	X
admet-3065	589	3	47	47	NUM
admet-3065	589	4	]	]	PUNCT
admet-3065	589	5	b.	b.	PROPN
admet-3065	589	6	dizman	dizman	PROPN
admet-3065	589	7	,	,	PUNCT
admet-3065	589	8	m.o	m.o	PROPN
admet-3065	589	9	.	.	PROPN
admet-3065	589	10	elasri	elasri	PROPN
admet-3065	589	11	,	,	PUNCT
admet-3065	589	12	l.j	l.j	PROPN
admet-3065	589	13	.	.	PROPN
admet-3065	589	14	mathias	mathias	PROPN
admet-3065	589	15	.	.	PUNCT
admet-3065	590	1	synthesis	synthesis	NOUN
admet-3065	590	2	and	and	CCONJ
admet-3065	590	3	antimicrobial	antimicrobial	ADJ
admet-3065	590	4	activities	activity	NOUN
admet-3065	590	5	of	of	ADP
admet-3065	590	6	new	new	ADJ
admet-3065	590	7	water	water	NOUN
admet-3065	590	8	-	-	PUNCT
admet-3065	590	9	soluble	soluble	ADJ
admet-3065	590	10	bisquaternary	bisquaternary	ADJ
admet-3065	590	11	ammonium	ammonium	NOUN
admet-3065	590	12	methacrylate	methacrylate	NOUN
admet-3065	590	13	polymers	polymer	NOUN
admet-3065	590	14	.	.	PUNCT
admet-3065	591	1	journal	journal	NOUN
admet-3065	591	2	of	of	ADP
admet-3065	591	3	applied	apply	VERB
admet-3065	591	4	polymer	polymer	NOUN
admet-3065	591	5	science	science	NOUN
admet-3065	591	6	94	94	NUM
admet-3065	591	7	(	(	PUNCT
admet-3065	591	8	2004	2004	NUM
admet-3065	591	9	)	)	PUNCT
admet-3065	591	10	635642	635642	NUM
admet-3065	591	11	.	.	PUNCT
admet-3065	592	1	https://doi.org/10.1002/app.20872	https://doi.org/10.1002/app.20872	NOUN
admet-3065	593	1	[	[	X
admet-3065	593	2	48	48	NUM
admet-3065	593	3	]	]	PUNCT
admet-3065	593	4	a.	a.	NOUN
admet-3065	593	5	akbarzadeh	akbarzadeh	PROPN
admet-3065	593	6	,	,	PUNCT
admet-3065	593	7	r.	r.	PROPN
admet-3065	593	8	rezaei	rezaei	PROPN
admet-3065	593	9	-	-	PUNCT
admet-3065	593	10	sadabady	sadabady	PROPN
admet-3065	593	11	,	,	PUNCT
admet-3065	593	12	s.	s.	PROPN
admet-3065	593	13	davaran	davaran	PROPN
admet-3065	593	14	,	,	PUNCT
admet-3065	593	15	s.w	s.w	PROPN
admet-3065	593	16	.	.	PROPN
admet-3065	593	17	joo	joo	PROPN
admet-3065	593	18	,	,	PUNCT
admet-3065	593	19	n.	n.	PROPN
admet-3065	593	20	zarghami	zarghami	PROPN
admet-3065	593	21	,	,	PUNCT
admet-3065	593	22	y.	y.	PROPN
admet-3065	593	23	hanifehpour	hanifehpour	VERB
admet-3065	593	24	.	.	PUNCT
admet-3065	594	1	liposome	liposome	NOUN
admet-3065	594	2	:	:	PUNCT
admet-3065	594	3	classification	classification	NOUN
admet-3065	594	4	,	,	PUNCT
admet-3065	594	5	preparation	preparation	NOUN
admet-3065	594	6	,	,	PUNCT
admet-3065	594	7	and	and	CCONJ
admet-3065	594	8	applications	application	NOUN
admet-3065	594	9	.	.	PUNCT
admet-3065	595	1	nanoscale	nanoscale	NOUN
admet-3065	595	2	research	research	NOUN
admet-3065	595	3	letters	letter	NOUN
admet-3065	595	4	8	8	NUM
admet-3065	595	5	(	(	PUNCT
admet-3065	595	6	2013	2013	NUM
admet-3065	595	7	)	)	PUNCT
admet-3065	595	8	102	102	NUM
admet-3065	595	9	-	-	SYM
admet-3065	595	10	102	102	NUM
admet-3065	595	11	.	.	PUNCT
admet-3065	596	1	https://doi.org/10.1186/1556-276x-8-102	https://doi.org/10.1186/1556-276x-8-102	NUM
admet-3065	597	1	[	[	X
admet-3065	597	2	49	49	NUM
admet-3065	597	3	]	]	PUNCT
admet-3065	597	4	f.	f.	PROPN
admet-3065	597	5	sakurai	sakurai	PROPN
admet-3065	597	6	,	,	PUNCT
admet-3065	597	7	t.	t.	PROPN
admet-3065	597	8	nishioka	nishioka	PROPN
admet-3065	597	9	,	,	PUNCT
admet-3065	597	10	h.	h.	PROPN
admet-3065	597	11	saito	saito	PROPN
admet-3065	597	12	,	,	PUNCT
admet-3065	597	13	t.	t.	PROPN
admet-3065	597	14	baba	baba	PROPN
admet-3065	597	15	,	,	PUNCT
admet-3065	597	16	a.	a.	NOUN
admet-3065	597	17	okuda	okuda	PROPN
admet-3065	597	18	,	,	PUNCT
admet-3065	597	19	o.	o.	PROPN
admet-3065	597	20	matsumoto	matsumoto	PROPN
admet-3065	597	21	.	.	PUNCT
admet-3065	598	1	interaction	interaction	NOUN
admet-3065	598	2	between	between	ADP
admet-3065	598	3	dnacationic	dnacationic	ADJ
admet-3065	598	4	liposome	liposome	NOUN
admet-3065	598	5	complexes	complex	NOUN
admet-3065	598	6	and	and	CCONJ
admet-3065	598	7	erythrocytes	erythrocyte	NOUN
admet-3065	598	8	is	be	AUX
admet-3065	598	9	an	an	DET
admet-3065	598	10	important	important	ADJ
admet-3065	598	11	factor	factor	NOUN
admet-3065	598	12	in	in	ADP
admet-3065	598	13	systemic	systemic	ADJ
admet-3065	598	14	gene	gene	NOUN
admet-3065	598	15	transfer	transfer	NOUN
admet-3065	598	16	via	via	ADP
admet-3065	598	17	the	the	DET
admet-3065	598	18	intravenous	intravenous	ADJ
admet-3065	598	19	route	route	NOUN
admet-3065	598	20	in	in	ADP
admet-3065	598	21	mice	mouse	NOUN
admet-3065	598	22	:	:	PUNCT
admet-3065	598	23	the	the	DET
admet-3065	598	24	role	role	NOUN
admet-3065	598	25	of	of	ADP
admet-3065	598	26	the	the	DET
admet-3065	598	27	neutral	neutral	ADJ
admet-3065	598	28	helper	helper	NOUN
admet-3065	598	29	lipid	lipid	NOUN
admet-3065	598	30	.	.	PUNCT
admet-3065	599	1	gene	gene	NOUN
admet-3065	599	2	therapy	therapy	NOUN
admet-3065	599	3	8	8	NUM
admet-3065	599	4	(	(	PUNCT
admet-3065	599	5	2001	2001	NUM
admet-3065	599	6	)	)	PUNCT
admet-3065	599	7	677	677	NUM
admet-3065	599	8	-	-	SYM
admet-3065	599	9	686	686	NUM
admet-3065	599	10	.	.	PUNCT
admet-3065	600	1	https://doi.org/10.1038/sj.gt.3301460	https://doi.org/10.1038/sj.gt.3301460	NOUN
admet-3065	601	1	[	[	X
admet-3065	601	2	50	50	NUM
admet-3065	601	3	]	]	X
admet-3065	601	4	p.k	p.k	PROPN
admet-3065	601	5	.	.	PROPN
admet-3065	601	6	maiti	maiti	PROPN
admet-3065	601	7	,	,	PUNCT
admet-3065	601	8	f.	f.	PROPN
admet-3065	601	9	leclercq	leclercq	PROPN
admet-3065	601	10	,	,	PUNCT
admet-3065	601	11	m.e	m.e	PROPN
admet-3065	601	12	.	.	PROPN
admet-3065	601	13	nabel	nabel	PROPN
admet-3065	601	14	,	,	PUNCT
admet-3065	601	15	m.	m.	NOUN
admet-3065	601	16	antonietti	antonietti	PROPN
admet-3065	601	17	.	.	PUNCT
admet-3065	602	1	gemini	gemini	PROPN
admet-3065	602	2	surfactants	surfactant	NOUN
admet-3065	602	3	at	at	ADP
admet-3065	602	4	the	the	DET
admet-3065	602	5	air	air	NOUN
admet-3065	602	6	/	/	SYM
admet-3065	602	7	water	water	NOUN
admet-3065	602	8	interface	interface	NOUN
admet-3065	602	9	:	:	PUNCT
admet-3065	602	10	a	a	DET
admet-3065	602	11	fully	fully	ADV
admet-3065	602	12	atomistic	atomistic	ADJ
admet-3065	602	13	molecular	molecular	ADJ
admet-3065	602	14	dynamics	dynamic	NOUN
admet-3065	602	15	study	study	NOUN
admet-3065	602	16	.	.	PUNCT
admet-3065	603	1	the	the	DET
admet-3065	603	2	journal	journal	NOUN
admet-3065	603	3	of	of	ADP
admet-3065	603	4	physical	physical	ADJ
admet-3065	603	5	chemistry	chemistry	NOUN
admet-3065	603	6	b	b	PROPN
admet-3065	603	7	122	122	NUM
admet-3065	603	8	(	(	PUNCT
admet-3065	603	9	2018	2018	NUM
admet-3065	603	10	)	)	PUNCT
admet-3065	603	11	874	874	NUM
admet-3065	603	12	-	-	SYM
admet-3065	603	13	883	883	NUM
admet-3065	603	14	.	.	PUNCT
admet-3065	604	1	https://doi.org/10.1021/jp063343d	https://doi.org/10.1021/jp063343d	PROPN
admet-3065	604	2	[	[	X
admet-3065	604	3	51	51	NUM
admet-3065	604	4	]	]	X
admet-3065	604	5	a.s	a.s	PROPN
admet-3065	604	6	.	.	PROPN
admet-3065	604	7	narang	narang	PROPN
admet-3065	604	8	,	,	PUNCT
admet-3065	604	9	l.	l.	PROPN
admet-3065	604	10	thoma	thoma	PROPN
admet-3065	604	11	,	,	PUNCT
admet-3065	604	12	d.d	d.d	PROPN
admet-3065	604	13	.	.	PROPN
admet-3065	604	14	miller	miller	PROPN
admet-3065	604	15	,	,	PUNCT
admet-3065	604	16	r.i	r.i	PROPN
admet-3065	604	17	.	.	PROPN
admet-3065	604	18	mahato	mahato	PROPN
admet-3065	604	19	.	.	PUNCT
admet-3065	605	1	cationic	cationic	NOUN
admet-3065	605	2	lipids	lipid	NOUN
admet-3065	605	3	with	with	ADP
admet-3065	605	4	increased	increase	VERB
admet-3065	605	5	dna	dna	NOUN
admet-3065	605	6	binding	bind	VERB
admet-3065	605	7	affinity	affinity	NOUN
admet-3065	605	8	for	for	ADP
admet-3065	605	9	nonviral	nonviral	ADJ
admet-3065	605	10	gene	gene	NOUN
admet-3065	605	11	transfer	transfer	NOUN
admet-3065	605	12	in	in	ADP
admet-3065	605	13	dividing	divide	VERB
admet-3065	605	14	and	and	CCONJ
admet-3065	605	15	nondividing	nondivide	VERB
admet-3065	605	16	cells	cell	NOUN
admet-3065	605	17	.	.	PUNCT
admet-3065	606	1	bioconjugate	bioconjugate	NOUN
admet-3065	606	2	chemistry	chemistry	NOUN
admet-3065	606	3	16	16	NUM
admet-3065	606	4	(	(	PUNCT
admet-3065	606	5	2005	2005	NUM
admet-3065	606	6	)	)	PUNCT
admet-3065	606	7	156168	156168	NUM
admet-3065	606	8	.	.	PUNCT
admet-3065	607	1	https://doi.org/10.1021/bc049818q	https://doi.org/10.1021/bc049818q	VERB
admet-3065	607	2	[	[	X
admet-3065	607	3	52	52	NUM
admet-3065	607	4	]	]	SYM
admet-3065	607	5	h.k	h.k	PROPN
admet-3065	607	6	.	.	PROPN
admet-3065	607	7	hall	hall	PROPN
admet-3065	607	8	,	,	PUNCT
admet-3065	607	9	jr	jr	PROPN
admet-3065	607	10	.	.	PROPN
admet-3065	607	11	correlation	correlation	NOUN
admet-3065	607	12	of	of	ADP
admet-3065	607	13	the	the	DET
admet-3065	607	14	base	base	NOUN
admet-3065	607	15	strengths	strength	NOUN
admet-3065	607	16	of	of	ADP
admet-3065	607	17	amines	amine	NOUN
admet-3065	607	18	.	.	PUNCT
admet-3065	608	1	journal	journal	NOUN
admet-3065	608	2	of	of	ADP
admet-3065	608	3	the	the	DET
admet-3065	608	4	american	american	PROPN
admet-3065	608	5	chemical	chemical	PROPN
admet-3065	608	6	society	society	PROPN
admet-3065	608	7	79	79	NUM
admet-3065	608	8	(	(	PUNCT
admet-3065	608	9	1957	1957	NUM
admet-3065	608	10	)	)	PUNCT
admet-3065	608	11	5441	5441	NUM
admet-3065	608	12	-	-	SYM
admet-3065	608	13	5444	5444	NUM
admet-3065	608	14	.	.	PUNCT
admet-3065	609	1	https://doi.org/10.1021/ja01577a030	https://doi.org/10.1021/ja01577a030	NOUN
admet-3065	609	2	[	[	PUNCT
admet-3065	609	3	53	53	NUM
admet-3065	609	4	]	]	PUNCT
admet-3065	609	5	j.	j.	PROPN
admet-3065	609	6	buck	buck	PROPN
admet-3065	609	7	,	,	PUNCT
admet-3065	609	8	p.	p.	PROPN
admet-3065	609	9	grossen	grossen	PROPN
admet-3065	609	10	,	,	PUNCT
admet-3065	609	11	p.r	p.r	PROPN
admet-3065	609	12	.	.	PROPN
admet-3065	609	13	cullis	cullis	PROPN
admet-3065	609	14	,	,	PUNCT
admet-3065	609	15	d.	d.	PROPN
admet-3065	609	16	witzigmann	witzigmann	PROPN
admet-3065	609	17	,	,	PUNCT
admet-3065	609	18	p.	p.	NOUN
admet-3065	609	19	luciani	luciani	PROPN
admet-3065	609	20	.	.	PUNCT
admet-3065	610	1	lipid	lipid	NOUN
admet-3065	610	2	-	-	PUNCT
admet-3065	610	3	based	base	VERB
admet-3065	610	4	dna	dna	PROPN
admet-3065	610	5	therapeutics	therapeutic	NOUN
admet-3065	610	6	:	:	PUNCT
admet-3065	610	7	hallmarks	hallmark	NOUN
admet-3065	610	8	of	of	ADP
admet-3065	610	9	non	non	ADJ
admet-3065	610	10	-	-	ADJ
admet-3065	610	11	viral	viral	ADJ
admet-3065	610	12	gene	gene	NOUN
admet-3065	610	13	delivery	delivery	NOUN
admet-3065	610	14	.	.	PUNCT
admet-3065	611	1	acs	acs	PROPN
admet-3065	611	2	nano	nano	VERB
admet-3065	611	3	13	13	NUM
admet-3065	611	4	(	(	PUNCT
admet-3065	611	5	2019	2019	NUM
admet-3065	611	6	)	)	PUNCT
admet-3065	611	7	3754	3754	NUM
admet-3065	611	8	-	-	SYM
admet-3065	611	9	3782	3782	NUM
admet-3065	611	10	.	.	PUNCT
admet-3065	612	1	https://doi.org/10.1021/acsnano.8b07858	https://doi.org/10.1021/acsnano.8b07858	NOUN
admet-3065	612	2	[	[	X
admet-3065	612	3	54	54	NUM
admet-3065	612	4	]	]	X
admet-3065	612	5	d.a	d.a	PROPN
admet-3065	612	6	.	.	PROPN
admet-3065	612	7	balazs	balazs	PROPN
admet-3065	612	8	,	,	PUNCT
admet-3065	612	9	w.	w.	PROPN
admet-3065	612	10	godbey	godbey	PROPN
admet-3065	612	11	.	.	PUNCT
admet-3065	613	1	liposomes	liposome	NOUN
admet-3065	613	2	for	for	ADP
admet-3065	613	3	use	use	NOUN
admet-3065	613	4	in	in	ADP
admet-3065	613	5	gene	gene	NOUN
admet-3065	613	6	delivery	delivery	NOUN
admet-3065	613	7	.	.	PUNCT
admet-3065	614	1	journal	journal	NOUN
admet-3065	614	2	of	of	ADP
admet-3065	614	3	drug	drug	NOUN
admet-3065	614	4	delivery	delivery	NOUN
admet-3065	614	5	2011	2011	NUM
admet-3065	614	6	(	(	PUNCT
admet-3065	614	7	2011	2011	NUM
admet-3065	614	8	)	)	PUNCT
admet-3065	614	9	326497	326497	NUM
admet-3065	614	10	-	-	SYM
admet-3065	614	11	326497	326497	NUM
admet-3065	614	12	.	.	PUNCT
admet-3065	615	1	https://doi.org/10.1155/2011/326497	https://doi.org/10.1155/2011/326497	PROPN
admet-3065	616	1	[	[	X
admet-3065	616	2	55	55	NUM
admet-3065	616	3	]	]	X
admet-3065	616	4	m.d	m.d	PROPN
admet-3065	616	5	.	.	PROPN
admet-3065	616	6	kearns	kearns	PROPN
admet-3065	616	7	,	,	PUNCT
admet-3065	616	8	k.	k.	PROPN
admet-3065	616	9	patel	patel	PROPN
admet-3065	616	10	,	,	PUNCT
admet-3065	616	11	j.	j.	PROPN
admet-3065	616	12	dai	dai	PROPN
admet-3065	616	13	,	,	PUNCT
admet-3065	616	14	j.g	j.g	PROPN
admet-3065	616	15	.	.	PROPN
admet-3065	616	16	schellinger	schellinger	PROPN
admet-3065	616	17	,	,	PUNCT
admet-3065	616	18	c.c	c.c	PROPN
admet-3065	616	19	.	.	PROPN
admet-3065	616	20	appeldoorn	appeldoorn	PROPN
admet-3065	616	21	,	,	PUNCT
admet-3065	616	22	r.n	r.n	PROPN
admet-3065	616	23	.	.	PROPN
admet-3065	616	24	zuckermann	zuckermann	PROPN
admet-3065	616	25	.	.	PUNCT
admet-3065	617	1	2	2	NUM
admet-3065	617	2	-	-	PUNCT
admet-3065	617	3	aminoimidazole	aminoimidazole	NOUN
admet-3065	617	4	amino	amino	ADJ
admet-3065	617	5	acids	acid	NOUN
admet-3065	617	6	as	as	ADP
admet-3065	617	7	components	component	NOUN
admet-3065	617	8	of	of	ADP
admet-3065	617	9	the	the	DET
admet-3065	617	10	cellular	cellular	ADJ
admet-3065	617	11	stress	stress	NOUN
admet-3065	617	12	response	response	NOUN
admet-3065	617	13	.	.	PUNCT
admet-3065	618	1	biochemistry	biochemistry	NOUN
admet-3065	618	2	47	47	NUM
admet-3065	618	3	(	(	PUNCT
admet-3065	618	4	2008	2008	NUM
admet-3065	618	5	)	)	PUNCT
admet-3065	618	6	9224	9224	NUM
admet-3065	618	7	-	-	SYM
admet-3065	618	8	9239	9239	NUM
admet-3065	618	9	.	.	PUNCT
admet-3065	619	1	https://doi.org/10.1021/jm100306a	https://doi.org/10.1021/jm100306a	PUNCT
admet-3065	620	1	[	[	X
admet-3065	620	2	56	56	NUM
admet-3065	620	3	]	]	X
admet-3065	620	4	a.j	a.j	PROPN
admet-3065	620	5	.	.	PROPN
admet-3065	620	6	lin	lin	PROPN
admet-3065	620	7	,	,	PUNCT
admet-3065	620	8	n.l	n.l	PROPN
admet-3065	620	9	.	.	PROPN
admet-3065	620	10	slack	slack	PROPN
admet-3065	620	11	,	,	PUNCT
admet-3065	620	12	a.	a.	PROPN
admet-3065	620	13	ahmad	ahmad	PROPN
admet-3065	620	14	,	,	PUNCT
admet-3065	620	15	c.x	c.x	PROPN
admet-3065	620	16	.	.	PROPN
admet-3065	620	17	george	george	PROPN
admet-3065	620	18	,	,	PUNCT
admet-3065	620	19	c.e	c.e	PROPN
admet-3065	620	20	.	.	PROPN
admet-3065	620	21	samuel	samuel	PROPN
admet-3065	620	22	,	,	PUNCT
admet-3065	620	23	c.r	c.r	PROPN
admet-3065	620	24	.	.	PROPN
admet-3065	620	25	safinya	safinya	PROPN
admet-3065	620	26	.	.	PUNCT
admet-3065	621	1	three	three	NUM
admet-3065	621	2	-	-	PUNCT
admet-3065	621	3	dimensional	dimensional	ADJ
admet-3065	621	4	imaging	imaging	NOUN
admet-3065	621	5	of	of	ADP
admet-3065	621	6	lipid	lipid	ADJ
admet-3065	621	7	gene	gene	NOUN
admet-3065	621	8	-	-	PUNCT
admet-3065	621	9	carrier	carrier	NOUN
admet-3065	621	10	:	:	PUNCT
admet-3065	621	11	membrane	membrane	NOUN
admet-3065	621	12	charge	charge	NOUN
admet-3065	621	13	density	density	NOUN
admet-3065	621	14	controls	control	VERB
admet-3065	621	15	universal	universal	ADJ
admet-3065	621	16	transfection	transfection	NOUN
admet-3065	621	17	behavior	behavior	NOUN
admet-3065	621	18	in	in	ADP
admet-3065	621	19	lamellar	lamellar	ADJ
admet-3065	621	20	cationic	cationic	ADJ
admet-3065	621	21	liposome	liposome	NOUN
admet-3065	621	22	-	-	PUNCT
admet-3065	621	23	dna	dna	NOUN
admet-3065	621	24	complexes	complex	NOUN
admet-3065	621	25	.	.	PUNCT
admet-3065	622	1	biophysical	biophysical	ADJ
admet-3065	622	2	journal	journal	NOUN
admet-3065	622	3	84	84	NUM
admet-3065	622	4	(	(	PUNCT
admet-3065	622	5	2003	2003	NUM
admet-3065	622	6	)	)	PUNCT
admet-3065	622	7	3307	3307	NUM
admet-3065	622	8	-	-	SYM
admet-3065	622	9	3316	3316	NUM
admet-3065	622	10	.	.	PUNCT
admet-3065	623	1	https://doi.org/10.1016/s0006-3495(03)70055-1	https://doi.org/10.1016/s0006-3495(03)70055-1	NOUN
admet-3065	624	1	[	[	X
admet-3065	624	2	57	57	NUM
admet-3065	624	3	]	]	PUNCT
admet-3065	624	4	h.	h.	PROPN
admet-3065	624	5	farhood	farhood	PROPN
admet-3065	624	6	,	,	PUNCT
admet-3065	624	7	n.	n.	PROPN
admet-3065	624	8	serbina	serbina	PROPN
admet-3065	624	9	,	,	PUNCT
admet-3065	624	10	l.	l.	PROPN
admet-3065	624	11	huang	huang	PROPN
admet-3065	624	12	.	.	PUNCT
admet-3065	625	1	the	the	DET
admet-3065	625	2	role	role	NOUN
admet-3065	625	3	of	of	ADP
admet-3065	625	4	dioleoyl	dioleoyl	ADJ
admet-3065	625	5	phosphatidylethanolamine	phosphatidylethanolamine	PROPN
admet-3065	625	6	in	in	ADP
admet-3065	625	7	cationic	cationic	ADJ
admet-3065	625	8	liposome	liposome	NOUN
admet-3065	625	9	mediated	mediate	VERB
admet-3065	625	10	gene	gene	NOUN
admet-3065	625	11	transfer	transfer	NOUN
admet-3065	625	12	.	.	PUNCT
admet-3065	626	1	biomembranes	biomembrane	VERB
admet-3065	626	2	1235	1235	NUM
admet-3065	626	3	(	(	PUNCT
admet-3065	626	4	1995	1995	NUM
admet-3065	626	5	)	)	PUNCT
admet-3065	626	6	289	289	NUM
admet-3065	626	7	-	-	SYM
admet-3065	626	8	295	295	NUM
admet-3065	626	9	.	.	PUNCT
admet-3065	627	1	https://doi.org/10.1016/0005-2736(95)80016-9	https://doi.org/10.1016/0005-2736(95)80016-9	ADJ
admet-3065	627	2	[	[	X
admet-3065	627	3	58	58	NUM
admet-3065	627	4	]	]	PUNCT
admet-3065	627	5	x.	x.	PROPN
admet-3065	627	6	gao	gao	PROPN
admet-3065	627	7	,	,	PUNCT
admet-3065	627	8	l.	l.	PROPN
admet-3065	627	9	huang	huang	PROPN
admet-3065	627	10	.	.	PUNCT
admet-3065	628	1	a	a	DET
admet-3065	628	2	novel	novel	ADJ
admet-3065	628	3	cationic	cationic	NOUN
admet-3065	628	4	liposome	liposome	NOUN
admet-3065	628	5	reagent	reagent	NOUN
admet-3065	628	6	for	for	ADP
admet-3065	628	7	efficient	efficient	ADJ
admet-3065	628	8	transfection	transfection	NOUN
admet-3065	628	9	of	of	ADP
admet-3065	628	10	mammalian	mammalian	ADJ
admet-3065	628	11	cells	cell	NOUN
admet-3065	628	12	.	.	PUNCT
admet-3065	629	1	biochemical	biochemical	ADJ
admet-3065	629	2	and	and	CCONJ
admet-3065	629	3	biophysical	biophysical	ADJ
admet-3065	629	4	research	research	NOUN
admet-3065	629	5	communications	communication	NOUN
admet-3065	629	6	179	179	NUM
admet-3065	629	7	(	(	PUNCT
admet-3065	629	8	1991	1991	NUM
admet-3065	629	9	)	)	PUNCT
admet-3065	629	10	280	280	NUM
admet-3065	629	11	-	-	SYM
admet-3065	629	12	285	285	NUM
admet-3065	629	13	.	.	PUNCT
admet-3065	630	1	https://doi.org/10.1016/0006-291x(91)91366-k	https://doi.org/10.1016/0006-291x(91)91366-k	PROPN
admet-3065	630	2	https://doi.org/10.1016/j.lfs.2022.120375	https://doi.org/10.1016/j.lfs.2022.120375	PROPN
admet-3065	630	3	.	.	PUNCT
admet-3065	631	1	https://doi.org/10.1038/83324	https://doi.org/10.1038/83324	PROPN
admet-3065	631	2	.	.	PUNCT
admet-3065	632	1	https://doi.org/10.1046/j.1365-201x.2003.01093.x	https://doi.org/10.1046/j.1365-201x.2003.01093.x	PROPN
admet-3065	632	2	.	.	PUNCT
admet-3065	633	1	https://doi.org/10.1046/j.1365-201x.2003.01093.x	https://doi.org/10.1046/j.1365-201x.2003.01093.x	PROPN
admet-3065	633	2	.	.	PUNCT
admet-3065	634	1	https://doi.org/10.1016/j.addr.2006.09.009	https://doi.org/10.1016/j.addr.2006.09.009	PROPN
admet-3065	634	2	.	.	PUNCT
admet-3065	635	1	https://doi.org/10.1016/s0022-2836(64)80115-7	https://doi.org/10.1016/s0022-2836(64)80115-7	NOUN
admet-3065	635	2	https://doi.org/10.1002/app.20872	https://doi.org/10.1002/app.20872	PROPN
admet-3065	635	3	https://doi.org/10.1186/1556-276x-8-102	https://doi.org/10.1186/1556-276x-8-102	PROPN
admet-3065	635	4	.	.	PUNCT
admet-3065	636	1	https://doi.org/10.1038/sj.gt.3301460	https://doi.org/10.1038/sj.gt.3301460	PROPN
admet-3065	636	2	https://doi.org/10.1021/jp063343d	https://doi.org/10.1021/jp063343d	PROPN
admet-3065	636	3	https://doi.org/10.1021/bc049818q	https://doi.org/10.1021/bc049818q	NOUN
admet-3065	636	4	https://doi.org/10.1021/ja01577a030	https://doi.org/10.1021/ja01577a030	PROPN
admet-3065	636	5	https://doi.org/10.1021/acsnano.8b07858	https://doi.org/10.1021/acsnano.8b07858	NOUN
admet-3065	636	6	https://doi.org/10.1155/2011/326497	https://doi.org/10.1155/2011/326497	PROPN
admet-3065	636	7	https://doi.org/10.1021/jm100306a	https://doi.org/10.1021/jm100306a	NOUN
admet-3065	636	8	https://doi.org/10.1016/s0006-3495(03)70055-1	https://doi.org/10.1016/s0006-3495(03)70055-1	VERB
admet-3065	637	1	https://doi.org/10.1016/0005-2736(95)80016-9	https://doi.org/10.1016/0005-2736(95)80016-9	ADJ
admet-3065	637	2	https://doi.org/10.1016/0006-291x(91)91366-k	https://doi.org/10.1016/0006-291x(91)91366-k	PROPN
admet-3065	637	3	e.	e.	PROPN
admet-3065	637	4	j.	j.	PROPN
admet-3065	637	5	saleh	saleh	PROPN
admet-3065	637	6	et	et	PROPN
admet-3065	637	7	al	al	PROPN
admet-3065	637	8	.	.	PROPN
admet-3065	637	9	admet	admet	PROPN
admet-3065	637	10	&	&	CCONJ
admet-3065	637	11	dmpk	dmpk	PROPN
admet-3065	637	12	00(0	00(0	PROPN
admet-3065	637	13	)	)	PUNCT
admet-3065	637	14	(	(	PUNCT
admet-3065	637	15	2025	2025	NUM
admet-3065	637	16	)	)	PUNCT
admet-3065	637	17	3065	3065	NUM
admet-3065	637	18	22	22	NUM
admet-3065	638	1	[	[	X
admet-3065	638	2	59	59	NUM
admet-3065	638	3	]	]	PUNCT
admet-3065	638	4	r.	r.	PROPN
admet-3065	638	5	leventis	leventis	PROPN
admet-3065	638	6	,	,	PUNCT
admet-3065	638	7	j.r	j.r	PROPN
admet-3065	638	8	.	.	PROPN
admet-3065	638	9	silvius	silvius	PROPN
admet-3065	638	10	.	.	PUNCT
admet-3065	639	1	interactions	interaction	NOUN
admet-3065	639	2	of	of	ADP
admet-3065	639	3	mammalian	mammalian	ADJ
admet-3065	639	4	cells	cell	NOUN
admet-3065	639	5	with	with	ADP
admet-3065	639	6	lipid	lipid	ADJ
admet-3065	639	7	dispersions	dispersion	NOUN
admet-3065	639	8	containing	contain	VERB
admet-3065	639	9	novel	novel	ADJ
admet-3065	639	10	metabolizable	metabolizable	ADJ
admet-3065	639	11	cationic	cationic	ADJ
admet-3065	639	12	amphiphiles	amphiphile	NOUN
admet-3065	639	13	.	.	PUNCT
admet-3065	640	1	biochimica	biochimica	PROPN
admet-3065	640	2	et	et	PROPN
admet-3065	640	3	biophysica	biophysica	PROPN
admet-3065	640	4	acta	acta	PROPN
admet-3065	640	5	-	-	PUNCT
admet-3065	640	6	biomembranes	biomembranes	PROPN
admet-3065	640	7	1023	1023	NUM
admet-3065	640	8	(	(	PUNCT
admet-3065	640	9	1990	1990	NUM
admet-3065	640	10	)	)	PUNCT
admet-3065	640	11	124132	124132	NUM
admet-3065	640	12	.	.	PUNCT
admet-3065	641	1	https://doi.org/10.1016/0005-2736(90)90017-i	https://doi.org/10.1016/0005-2736(90)90017-i	PROPN
admet-3065	642	1	[	[	X
admet-3065	642	2	60	60	NUM
admet-3065	642	3	]	]	X
admet-3065	642	4	r.	r.	PROPN
admet-3065	642	5	leventis	leventis	PROPN
admet-3065	642	6	,	,	PUNCT
admet-3065	642	7	j.r	j.r	PROPN
admet-3065	642	8	.	.	PROPN
admet-3065	642	9	silvius	silvius	PROPN
admet-3065	642	10	.	.	PUNCT
admet-3065	643	1	interactions	interaction	NOUN
admet-3065	643	2	of	of	ADP
admet-3065	643	3	mammalian	mammalian	ADJ
admet-3065	643	4	cells	cell	NOUN
admet-3065	643	5	with	with	ADP
admet-3065	643	6	lipid	lipid	ADJ
admet-3065	643	7	dispersions	dispersion	NOUN
admet-3065	643	8	containing	contain	VERB
admet-3065	643	9	novel	novel	ADJ
admet-3065	643	10	metabolizable	metabolizable	ADJ
admet-3065	643	11	cationic	cationic	ADJ
admet-3065	643	12	amphiphiles	amphiphile	NOUN
admet-3065	643	13	.	.	PUNCT
admet-3065	644	1	biomembranes	biomembrane	VERB
admet-3065	644	2	1023	1023	NUM
admet-3065	644	3	(	(	PUNCT
admet-3065	644	4	1990	1990	NUM
admet-3065	644	5	)	)	PUNCT
admet-3065	644	6	124	124	NUM
admet-3065	644	7	-	-	SYM
admet-3065	644	8	132	132	NUM
admet-3065	644	9	.	.	PUNCT
admet-3065	645	1	https://doi.org/10.1016/0005-2736(90)90017-i	https://doi.org/10.1016/0005-2736(90)90017-i	NOUN
admet-3065	646	1	[	[	X
admet-3065	646	2	61	61	NUM
admet-3065	646	3	]	]	X
admet-3065	646	4	d.	d.	PROPN
admet-3065	646	5	simberg	simberg	PROPN
admet-3065	646	6	,	,	PUNCT
admet-3065	646	7	s.	s.	PROPN
admet-3065	646	8	weisman	weisman	PROPN
admet-3065	646	9	,	,	PUNCT
admet-3065	646	10	y.	y.	PROPN
admet-3065	646	11	talmon	talmon	PROPN
admet-3065	646	12	,	,	PUNCT
admet-3065	646	13	y.	y.	PROPN
admet-3065	646	14	barenholz	barenholz	PROPN
admet-3065	646	15	.	.	PUNCT
admet-3065	647	1	dotap	dotap	NOUN
admet-3065	647	2	(	(	PUNCT
admet-3065	647	3	and	and	CCONJ
admet-3065	647	4	other	other	ADJ
admet-3065	647	5	cationic	cationic	ADJ
admet-3065	647	6	lipids	lipid	NOUN
admet-3065	647	7	):	):	PUNCT
admet-3065	647	8	chemistry	chemistry	NOUN
admet-3065	647	9	,	,	PUNCT
admet-3065	647	10	biophysics	biophysic	NOUN
admet-3065	647	11	,	,	PUNCT
admet-3065	647	12	and	and	CCONJ
admet-3065	647	13	transfection	transfection	NOUN
admet-3065	647	14	.	.	PUNCT
admet-3065	648	1	critical	critical	ADJ
admet-3065	648	2	reviews	review	NOUN
admet-3065	648	3	in	in	ADP
admet-3065	648	4	therapeutic	therapeutic	ADJ
admet-3065	648	5	drug	drug	NOUN
admet-3065	648	6	carrier	carrier	NOUN
admet-3065	648	7	systems	system	NOUN
admet-3065	648	8	21	21	NUM
admet-3065	648	9	(	(	PUNCT
admet-3065	648	10	2004	2004	NUM
admet-3065	648	11	)	)	PUNCT
admet-3065	648	12	257317	257317	NUM
admet-3065	648	13	.	.	PUNCT
admet-3065	649	1	https://doi.org/10.1615/critrevtherdrugcarriersyst.v21.i4.10	https://doi.org/10.1615/critrevtherdrugcarriersyst.v21.i4.10	PUNCT
admet-3065	650	1	[	[	X
admet-3065	650	2	62	62	NUM
admet-3065	650	3	]	]	PUNCT
admet-3065	650	4	j.	j.	PROPN
admet-3065	650	5	ju	ju	PROPN
admet-3065	650	6	,	,	PUNCT
admet-3065	650	7	m.l	m.l	PROPN
admet-3065	650	8	.	.	PROPN
admet-3065	650	9	huan	huan	PROPN
admet-3065	650	10	,	,	PUNCT
admet-3065	650	11	n.	n.	PROPN
admet-3065	650	12	wan	wan	PROPN
admet-3065	650	13	,	,	PUNCT
admet-3065	650	14	h.	h.	PROPN
admet-3065	650	15	qiu	qiu	PROPN
admet-3065	650	16	,	,	PUNCT
admet-3065	650	17	s.y	s.y	PROPN
admet-3065	650	18	.	.	PROPN
admet-3065	650	19	zhou	zhou	PROPN
admet-3065	650	20	,	,	PUNCT
admet-3065	650	21	b.l	b.l	PROPN
admet-3065	650	22	.	.	PROPN
admet-3065	650	23	zhang	zhang	PROPN
admet-3065	650	24	.	.	PUNCT
admet-3065	651	1	novel	novel	ADJ
admet-3065	651	2	cholesterol	cholesterol	NOUN
admet-3065	651	3	-	-	PUNCT
admet-3065	651	4	based	base	VERB
admet-3065	651	5	cationic	cationic	NOUN
admet-3065	651	6	lipids	lipid	NOUN
admet-3065	651	7	as	as	ADP
admet-3065	651	8	transfecting	transfecting	NOUN
admet-3065	651	9	agents	agent	NOUN
admet-3065	651	10	of	of	ADP
admet-3065	651	11	dna	dna	PROPN
admet-3065	651	12	for	for	ADP
admet-3065	651	13	efficient	efficient	ADJ
admet-3065	651	14	gene	gene	NOUN
admet-3065	651	15	delivery	delivery	NOUN
admet-3065	651	16	.	.	PUNCT
admet-3065	652	1	international	international	ADJ
admet-3065	652	2	journal	journal	NOUN
admet-3065	652	3	of	of	ADP
admet-3065	652	4	molecular	molecular	ADJ
admet-3065	652	5	sciences	science	NOUN
admet-3065	652	6	16	16	NUM
admet-3065	652	7	(	(	PUNCT
admet-3065	652	8	2015	2015	NUM
admet-3065	652	9	)	)	PUNCT
admet-3065	652	10	5666	5666	NUM
admet-3065	652	11	-	-	SYM
admet-3065	652	12	5681	5681	NUM
admet-3065	652	13	.	.	PUNCT
admet-3065	653	1	https://doi.org/10.3390/ijms16035666	https://doi.org/10.3390/ijms16035666	PROPN
admet-3065	654	1	[	[	X
admet-3065	654	2	63	63	NUM
admet-3065	654	3	]	]	PUNCT
admet-3065	654	4	s.	s.	PROPN
admet-3065	654	5	huang	huang	PROPN
admet-3065	654	6	,	,	PUNCT
admet-3065	654	7	h.	h.	PROPN
admet-3065	654	8	que	que	PROPN
admet-3065	654	9	,	,	PUNCT
admet-3065	654	10	m.	m.	PROPN
admet-3065	654	11	wang	wang	PROPN
admet-3065	654	12	,	,	PUNCT
admet-3065	654	13	x.	x.	PROPN
admet-3065	654	14	wei	wei	PROPN
admet-3065	654	15	.	.	PUNCT
admet-3065	655	1	mrna	mrna	PROPN
admet-3065	655	2	vaccines	vaccine	NOUN
admet-3065	655	3	as	as	ADP
admet-3065	655	4	cancer	cancer	NOUN
admet-3065	655	5	therapies	therapy	NOUN
admet-3065	655	6	.	.	PUNCT
admet-3065	656	1	chinese	chinese	ADJ
admet-3065	656	2	medical	medical	ADJ
admet-3065	656	3	journal	journal	PROPN
admet-3065	656	4	137	137	NUM
admet-3065	656	5	(	(	PUNCT
admet-3065	656	6	2024	2024	NUM
admet-3065	656	7	)	)	PUNCT
admet-3065	656	8	2979	2979	NUM
admet-3065	656	9	-	-	SYM
admet-3065	656	10	2995	2995	NUM
admet-3065	656	11	.	.	PUNCT
admet-3065	657	1	https://doi.org/10.1097/cm9.0000000000003455	https://doi.org/10.1097/cm9.0000000000003455	VERB
admet-3065	658	1	[	[	X
admet-3065	658	2	64	64	NUM
admet-3065	658	3	]	]	PUNCT
admet-3065	658	4	s.	s.	PROPN
admet-3065	658	5	jain	jain	PROPN
admet-3065	658	6	,	,	PUNCT
admet-3065	658	7	g.	g.	PROPN
admet-3065	658	8	zon	zon	PROPN
admet-3065	658	9	,	,	PUNCT
admet-3065	658	10	m.	m.	NOUN
admet-3065	658	11	sundaralingam	sundaralingam	PROPN
admet-3065	658	12	.	.	PUNCT
admet-3065	659	1	base	base	NOUN
admet-3065	659	2	only	only	ADV
admet-3065	659	3	binding	bind	VERB
admet-3065	659	4	of	of	ADP
admet-3065	659	5	spermine	spermine	NOUN
admet-3065	659	6	in	in	ADP
admet-3065	659	7	the	the	DET
admet-3065	659	8	deep	deep	ADJ
admet-3065	659	9	groove	groove	NOUN
admet-3065	659	10	of	of	ADP
admet-3065	659	11	the	the	DET
admet-3065	659	12	a	a	DET
admet-3065	659	13	-	-	PUNCT
admet-3065	659	14	dna	dna	NOUN
admet-3065	659	15	octamer	octamer	NOUN
admet-3065	659	16	d(gtgtacac	d(gtgtacac	PROPN
admet-3065	659	17	)	)	PUNCT
admet-3065	659	18	.	.	PUNCT
admet-3065	660	1	biochemistry	biochemistry	NOUN
admet-3065	660	2	28	28	NUM
admet-3065	660	3	(	(	PUNCT
admet-3065	660	4	1989	1989	NUM
admet-3065	660	5	)	)	PUNCT
admet-3065	660	6	2360	2360	NUM
admet-3065	660	7	-	-	SYM
admet-3065	660	8	2364	2364	NUM
admet-3065	660	9	.	.	PUNCT
admet-3065	661	1	https://doi.org/10.1021/bi00432a002	https://doi.org/10.1021/bi00432a002	VERB
admet-3065	662	1	[	[	X
admet-3065	662	2	65	65	NUM
admet-3065	662	3	]	]	X
admet-3065	662	4	n.j	n.j	PROPN
admet-3065	662	5	.	.	PROPN
admet-3065	662	6	zuidam	zuidam	PROPN
admet-3065	662	7	,	,	PUNCT
admet-3065	662	8	y.	y.	PROPN
admet-3065	662	9	barenholz	barenholz	PROPN
admet-3065	662	10	.	.	PUNCT
admet-3065	663	1	electrostatic	electrostatic	ADJ
admet-3065	663	2	and	and	CCONJ
admet-3065	663	3	structural	structural	ADJ
admet-3065	663	4	properties	property	NOUN
admet-3065	663	5	of	of	ADP
admet-3065	663	6	complexes	complex	NOUN
admet-3065	663	7	involving	involve	VERB
admet-3065	663	8	plasmid	plasmid	ADJ
admet-3065	663	9	dna	dna	NOUN
admet-3065	663	10	and	and	CCONJ
admet-3065	663	11	cationic	cationic	ADJ
admet-3065	663	12	lipids	lipid	NOUN
admet-3065	663	13	commonly	commonly	ADV
admet-3065	663	14	used	use	VERB
admet-3065	663	15	for	for	ADP
admet-3065	663	16	gene	gene	NOUN
admet-3065	663	17	delivery	delivery	NOUN
admet-3065	663	18	.	.	PUNCT
admet-3065	664	1	biochimica	biochimica	PROPN
admet-3065	664	2	et	et	PROPN
admet-3065	664	3	biophysica	biophysica	PROPN
admet-3065	664	4	acta	acta	PROPN
admet-3065	664	5	(	(	PUNCT
admet-3065	664	6	bba	bba	NOUN
admet-3065	664	7	)	)	PUNCT
admet-3065	664	8	biomembranes	biomembrane	VERB
admet-3065	664	9	1368	1368	NUM
admet-3065	664	10	(	(	PUNCT
admet-3065	664	11	1998	1998	NUM
admet-3065	664	12	)	)	PUNCT
admet-3065	664	13	115	115	NUM
admet-3065	664	14	-	-	SYM
admet-3065	664	15	128	128	NUM
admet-3065	664	16	.	.	PUNCT
admet-3065	665	1	https://doi.org/10.1016/s0005-2736(97)00187-9	https://doi.org/10.1016/s0005-2736(97)00187-9	NOUN
admet-3065	666	1	[	[	X
admet-3065	666	2	66	66	NUM
admet-3065	666	3	]	]	PUNCT
admet-3065	666	4	j.	j.	PROPN
admet-3065	666	5	zabner	zabner	PROPN
admet-3065	666	6	,	,	PUNCT
admet-3065	666	7	a.j	a.j	PROPN
admet-3065	666	8	.	.	PROPN
admet-3065	666	9	fasbender	fasbender	PROPN
admet-3065	666	10	,	,	PUNCT
admet-3065	666	11	t.	t.	PROPN
admet-3065	666	12	moninger	moninger	NOUN
admet-3065	666	13	,	,	PUNCT
admet-3065	666	14	k.a	k.a	PROPN
admet-3065	666	15	.	.	PROPN
admet-3065	666	16	poellinger	poellinger	PROPN
admet-3065	666	17	,	,	PUNCT
admet-3065	666	18	m.j	m.j	PROPN
admet-3065	666	19	.	.	PROPN
admet-3065	666	20	welsh	welsh	PROPN
admet-3065	666	21	.	.	PUNCT
admet-3065	667	1	cellular	cellular	ADJ
admet-3065	667	2	and	and	CCONJ
admet-3065	667	3	molecular	molecular	ADJ
admet-3065	667	4	barriers	barrier	NOUN
admet-3065	667	5	to	to	ADP
admet-3065	667	6	gene	gene	NOUN
admet-3065	667	7	transfer	transfer	NOUN
admet-3065	667	8	by	by	ADP
admet-3065	667	9	a	a	DET
admet-3065	667	10	cationic	cationic	ADJ
admet-3065	667	11	lipid	lipid	NOUN
admet-3065	667	12	.	.	PUNCT
admet-3065	668	1	the	the	DET
admet-3065	668	2	journal	journal	NOUN
admet-3065	668	3	of	of	ADP
admet-3065	668	4	biological	biological	ADJ
admet-3065	668	5	chemistry	chemistry	NOUN
admet-3065	668	6	270	270	NUM
admet-3065	668	7	(	(	PUNCT
admet-3065	668	8	1995	1995	NUM
admet-3065	668	9	)	)	PUNCT
admet-3065	668	10	18997	18997	NUM
admet-3065	668	11	-	-	SYM
admet-3065	668	12	19007	19007	NUM
admet-3065	668	13	.	.	PUNCT
admet-3065	669	1	https://doi.org/10.1074/jbc.270.32.18997	https://doi.org/10.1074/jbc.270.32.18997	NOUN
admet-3065	669	2	[	[	X
admet-3065	669	3	67	67	NUM
admet-3065	669	4	]	]	X
admet-3065	669	5	p.p	p.p	PROPN
admet-3065	669	6	.	.	PROPN
admet-3065	669	7	karmali	karmali	PROPN
admet-3065	669	8	,	,	PUNCT
admet-3065	669	9	a.	a.	PROPN
admet-3065	669	10	chaudhuri	chaudhuri	PROPN
admet-3065	669	11	.	.	PUNCT
admet-3065	670	1	cationic	cationic	ADJ
admet-3065	670	2	liposomes	liposome	NOUN
admet-3065	670	3	as	as	ADP
admet-3065	670	4	non‐viral	non‐viral	ADJ
admet-3065	670	5	carriers	carrier	NOUN
admet-3065	670	6	of	of	ADP
admet-3065	670	7	gene	gene	NOUN
admet-3065	670	8	medicines	medicine	NOUN
admet-3065	670	9	:	:	PUNCT
admet-3065	670	10	resolved	resolve	VERB
admet-3065	670	11	issues	issue	NOUN
admet-3065	670	12	,	,	PUNCT
admet-3065	670	13	open	open	ADJ
admet-3065	670	14	questions	question	NOUN
admet-3065	670	15	,	,	PUNCT
admet-3065	670	16	and	and	CCONJ
admet-3065	670	17	future	future	ADJ
admet-3065	670	18	promises	promise	NOUN
admet-3065	670	19	.	.	PUNCT
admet-3065	671	1	medicinal	medicinal	ADJ
admet-3065	671	2	research	research	NOUN
admet-3065	671	3	reviews	review	NOUN
admet-3065	671	4	27	27	NUM
admet-3065	671	5	(	(	PUNCT
admet-3065	671	6	2007	2007	NUM
admet-3065	671	7	)	)	PUNCT
admet-3065	671	8	696	696	NUM
admet-3065	671	9	-	-	SYM
admet-3065	671	10	722	722	NUM
admet-3065	671	11	.	.	PUNCT
admet-3065	672	1	https://doi.org/10.1002/med.20090	https://doi.org/10.1002/med.20090	NOUN
admet-3065	672	2	[	[	PUNCT
admet-3065	672	3	68	68	NUM
admet-3065	672	4	]	]	PUNCT
admet-3065	672	5	b.-k	b.-k	NOUN
admet-3065	672	6	.	.	PUNCT
admet-3065	673	1	kim	kim	PROPN
admet-3065	673	2	,	,	PUNCT
admet-3065	673	3	g.-b	g.-b	PROPN
admet-3065	673	4	.	.	PUNCT
admet-3065	673	5	hwang	hwang	PROPN
admet-3065	673	6	,	,	PUNCT
admet-3065	673	7	y.-b	y.-b	PROPN
admet-3065	673	8	.	.	PROPN
admet-3065	673	9	seu	seu	PROPN
admet-3065	673	10	,	,	PUNCT
admet-3065	673	11	j.-s	j.-	NOUN
admet-3065	673	12	.	.	PUNCT
admet-3065	674	1	choi	choi	NOUN
admet-3065	674	2	,	,	PUNCT
admet-3065	674	3	k.s	k.s	PROPN
admet-3065	674	4	.	.	PROPN
admet-3065	674	5	jin	jin	PROPN
admet-3065	674	6	,	,	PUNCT
admet-3065	674	7	k.-o	k.-o	PROPN
admet-3065	674	8	.	.	PUNCT
admet-3065	675	1	doh	doh	PROPN
admet-3065	675	2	.	.	PUNCT
admet-3065	675	3	dotap	dotap	PROPN
admet-3065	675	4	/	/	SYM
admet-3065	675	5	dope	dope	NOUN
admet-3065	675	6	ratio	ratio	NOUN
admet-3065	675	7	and	and	CCONJ
admet-3065	675	8	cell	cell	NOUN
admet-3065	675	9	type	type	NOUN
admet-3065	675	10	determine	determine	NOUN
admet-3065	675	11	transfection	transfection	NOUN
admet-3065	675	12	efficiency	efficiency	NOUN
admet-3065	675	13	with	with	ADP
admet-3065	675	14	dotap	dotap	NOUN
admet-3065	675	15	-	-	PUNCT
admet-3065	675	16	liposomes	liposome	NOUN
admet-3065	675	17	.	.	PUNCT
admet-3065	676	1	biochimica	biochimica	PROPN
admet-3065	676	2	et	et	PROPN
admet-3065	676	3	biophysica	biophysica	PROPN
admet-3065	676	4	actabiomembranes	actabiomembrane	NOUN
admet-3065	676	5	1848	1848	NUM
admet-3065	676	6	(	(	PUNCT
admet-3065	676	7	2015	2015	NUM
admet-3065	676	8	)	)	PUNCT
admet-3065	676	9	1996	1996	NUM
admet-3065	676	10	-	-	SYM
admet-3065	676	11	2001	2001	NUM
admet-3065	676	12	.	.	PUNCT
admet-3065	677	1	https://doi.org/10.1016/j.bbamem.2015.06.020	https://doi.org/10.1016/j.bbamem.2015.06.020	NOUN
admet-3065	677	2	[	[	X
admet-3065	677	3	69	69	NUM
admet-3065	677	4	]	]	PUNCT
admet-3065	677	5	i.	i.	PROPN
admet-3065	677	6	koltover	koltover	PROPN
admet-3065	677	7	,	,	PUNCT
admet-3065	677	8	t.	t.	PROPN
admet-3065	677	9	salditt	salditt	PROPN
admet-3065	677	10	,	,	PUNCT
admet-3065	677	11	j.o	j.o	PROPN
admet-3065	677	12	.	.	PROPN
admet-3065	677	13	rädler	rädler	PROPN
admet-3065	677	14	,	,	PUNCT
admet-3065	677	15	c.r	c.r	PROPN
admet-3065	677	16	.	.	PROPN
admet-3065	677	17	safinya	safinya	PROPN
admet-3065	677	18	.	.	PUNCT
admet-3065	678	1	an	an	DET
admet-3065	678	2	inverted	inverted	ADJ
admet-3065	678	3	hexagonal	hexagonal	ADJ
admet-3065	678	4	phase	phase	NOUN
admet-3065	678	5	of	of	ADP
admet-3065	678	6	cationic	cationic	ADJ
admet-3065	678	7	liposomedna	liposomedna	ADJ
admet-3065	678	8	complexes	complex	NOUN
admet-3065	678	9	related	relate	VERB
admet-3065	678	10	to	to	ADP
admet-3065	678	11	dna	dna	PROPN
admet-3065	678	12	release	release	NOUN
admet-3065	678	13	and	and	CCONJ
admet-3065	678	14	delivery	delivery	NOUN
admet-3065	678	15	.	.	PUNCT
admet-3065	679	1	science	science	NOUN
admet-3065	679	2	281	281	NUM
admet-3065	679	3	(	(	PUNCT
admet-3065	679	4	1998	1998	NUM
admet-3065	679	5	)	)	PUNCT
admet-3065	679	6	78	78	NUM
admet-3065	679	7	-	-	SYM
admet-3065	679	8	81	81	NUM
admet-3065	679	9	.	.	PUNCT
admet-3065	680	1	https://doi.org/10.1126/science.281.5373.78	https://doi.org/10.1126/science.281.5373.78	NOUN
admet-3065	680	2	[	[	X
admet-3065	680	3	70	70	NUM
admet-3065	680	4	]	]	PUNCT
admet-3065	680	5	s.	s.	PROPN
admet-3065	680	6	chatterjee	chatterjee	PROPN
admet-3065	680	7	,	,	PUNCT
admet-3065	680	8	e.	e.	PROPN
admet-3065	680	9	kon	kon	PROPN
admet-3065	680	10	,	,	PUNCT
admet-3065	680	11	p.	p.	PROPN
admet-3065	680	12	sharma	sharma	PROPN
admet-3065	680	13	,	,	PUNCT
admet-3065	680	14	d.	d.	PROPN
admet-3065	680	15	peer	peer	PROPN
admet-3065	680	16	.	.	PUNCT
admet-3065	681	1	endosomal	endosomal	ADJ
admet-3065	681	2	escape	escape	NOUN
admet-3065	681	3	:	:	PUNCT
admet-3065	681	4	a	a	DET
admet-3065	681	5	bottleneck	bottleneck	NOUN
admet-3065	681	6	for	for	ADP
admet-3065	681	7	lnp	lnp	NOUN
admet-3065	681	8	-	-	PUNCT
admet-3065	681	9	mediated	mediate	VERB
admet-3065	681	10	therapeutics	therapeutic	NOUN
admet-3065	681	11	.	.	PUNCT
admet-3065	682	1	proceedings	proceeding	NOUN
admet-3065	682	2	of	of	ADP
admet-3065	682	3	the	the	DET
admet-3065	682	4	national	national	PROPN
admet-3065	682	5	academy	academy	PROPN
admet-3065	682	6	of	of	ADP
admet-3065	682	7	sciences	sciences	PROPN
admet-3065	682	8	121	121	NUM
admet-3065	682	9	(	(	PUNCT
admet-3065	682	10	2024	2024	NUM
admet-3065	682	11	)	)	PUNCT
admet-3065	682	12	2307800120	2307800120	NUM
admet-3065	682	13	.	.	PUNCT
admet-3065	683	1	https://doi.org/10.1073/pnas.2307800120	https://doi.org/10.1073/pnas.2307800120	ADJ
admet-3065	684	1	[	[	X
admet-3065	684	2	71	71	NUM
admet-3065	684	3	]	]	X
admet-3065	684	4	t.h	t.h	PROPN
admet-3065	684	5	.	.	PROPN
admet-3065	684	6	cheung	cheung	PROPN
admet-3065	684	7	,	,	PUNCT
admet-3065	684	8	m.s	m.s	PROPN
admet-3065	684	9	.	.	PROPN
admet-3065	684	10	shoichet	shoichet	PROPN
admet-3065	684	11	.	.	PUNCT
admet-3065	685	1	the	the	DET
admet-3065	685	2	interplay	interplay	NOUN
admet-3065	685	3	of	of	ADP
admet-3065	685	4	endosomal	endosomal	ADJ
admet-3065	685	5	escape	escape	NOUN
admet-3065	685	6	and	and	CCONJ
admet-3065	685	7	rna	rna	NOUN
admet-3065	685	8	release	release	NOUN
admet-3065	685	9	from	from	ADP
admet-3065	685	10	polymeric	polymeric	ADJ
admet-3065	685	11	nanoparticles	nanoparticle	NOUN
admet-3065	685	12	.	.	PUNCT
admet-3065	686	1	langmuir	langmuir	PROPN
admet-3065	686	2	41	41	NUM
admet-3065	686	3	(	(	PUNCT
admet-3065	686	4	2025	2025	NUM
admet-3065	686	5	)	)	PUNCT
admet-3065	686	6	7174	7174	NUM
admet-3065	686	7	-	-	SYM
admet-3065	686	8	7190	7190	NUM
admet-3065	686	9	.	.	PUNCT
admet-3065	687	1	https://doi.org/10.1021/acs.langmuir.4c05176	https://doi.org/10.1021/acs.langmuir.4c05176	NOUN
admet-3065	688	1	[	[	X
admet-3065	688	2	72	72	NUM
admet-3065	688	3	]	]	X
admet-3065	688	4	i.m	i.m	PROPN
admet-3065	688	5	.	.	PROPN
admet-3065	688	6	degors	degor	NOUN
admet-3065	688	7	,	,	PUNCT
admet-3065	688	8	c.	c.	PROPN
admet-3065	688	9	wang	wang	PROPN
admet-3065	688	10	,	,	PUNCT
admet-3065	688	11	z.u	z.u	PROPN
admet-3065	688	12	.	.	PROPN
admet-3065	688	13	rehman	rehman	PROPN
admet-3065	688	14	,	,	PUNCT
admet-3065	688	15	i.s	i.s	PROPN
admet-3065	688	16	.	.	PROPN
admet-3065	688	17	zuhorn	zuhorn	PROPN
admet-3065	688	18	.	.	PUNCT
admet-3065	689	1	carriers	carrier	NOUN
admet-3065	689	2	break	break	VERB
admet-3065	689	3	barriers	barrier	NOUN
admet-3065	689	4	in	in	ADP
admet-3065	689	5	drug	drug	NOUN
admet-3065	689	6	delivery	delivery	NOUN
admet-3065	689	7	:	:	PUNCT
admet-3065	689	8	endocytosis	endocytosis	NOUN
admet-3065	689	9	and	and	CCONJ
admet-3065	689	10	endosomal	endosomal	ADJ
admet-3065	689	11	escape	escape	NOUN
admet-3065	689	12	of	of	ADP
admet-3065	689	13	gene	gene	NOUN
admet-3065	689	14	delivery	delivery	NOUN
admet-3065	689	15	vectors	vector	NOUN
admet-3065	689	16	.	.	PUNCT
admet-3065	690	1	accounts	account	NOUN
admet-3065	690	2	of	of	ADP
admet-3065	690	3	chemical	chemical	ADJ
admet-3065	690	4	research	research	NOUN
admet-3065	690	5	52	52	NUM
admet-3065	690	6	(	(	PUNCT
admet-3065	690	7	2019	2019	NUM
admet-3065	690	8	)	)	PUNCT
admet-3065	690	9	17501760	17501760	NUM
admet-3065	690	10	.	.	PUNCT
admet-3065	691	1	https://doi.org/10.1021/acs.accounts.9b00177	https://doi.org/10.1021/acs.accounts.9b00177	PRON
admet-3065	692	1	[	[	X
admet-3065	692	2	73	73	NUM
admet-3065	692	3	]	]	X
admet-3065	692	4	[	[	X
admet-3065	692	5	70	70	NUM
admet-3065	692	6	]	]	X
admet-3065	692	7	i.s	i.s	PROPN
admet-3065	692	8	.	.	PROPN
admet-3065	693	1	zuhorn	zuhorn	PROPN
admet-3065	693	2	,	,	PUNCT
admet-3065	693	3	u.	u.	PROPN
admet-3065	693	4	bakowsky	bakowsky	PROPN
admet-3065	693	5	,	,	PUNCT
admet-3065	693	6	e.	e.	PROPN
admet-3065	693	7	polushkin	polushkin	PROPN
admet-3065	693	8	,	,	PUNCT
admet-3065	693	9	w.h	w.h	PROPN
admet-3065	693	10	.	.	PROPN
admet-3065	693	11	visser	visser	PROPN
admet-3065	693	12	,	,	PUNCT
admet-3065	693	13	m.c	m.c	PROPN
admet-3065	693	14	.	.	PROPN
admet-3065	693	15	stuart	stuart	PROPN
admet-3065	693	16	,	,	PUNCT
admet-3065	693	17	j.b	j.b	PROPN
admet-3065	693	18	.	.	PROPN
admet-3065	693	19	engberts	engbert	NOUN
admet-3065	693	20	,	,	PUNCT
admet-3065	693	21	d.	d.	PROPN
admet-3065	693	22	hoekstra	hoekstra	PROPN
admet-3065	693	23	.	.	PUNCT
admet-3065	694	1	nonbilayer	nonbilayer	PROPN
admet-3065	694	2	phase	phase	NOUN
admet-3065	694	3	of	of	ADP
admet-3065	694	4	lipoplex	lipoplex	ADJ
admet-3065	694	5	-	-	PUNCT
admet-3065	694	6	membrane	membrane	NOUN
admet-3065	694	7	mixture	mixture	NOUN
admet-3065	694	8	determines	determine	VERB
admet-3065	694	9	endosomal	endosomal	ADJ
admet-3065	694	10	escape	escape	NOUN
admet-3065	694	11	of	of	ADP
admet-3065	694	12	genetic	genetic	ADJ
admet-3065	694	13	cargo	cargo	NOUN
admet-3065	694	14	and	and	CCONJ
admet-3065	694	15	transfection	transfection	NOUN
admet-3065	694	16	efficiency	efficiency	NOUN
admet-3065	694	17	.	.	PUNCT
admet-3065	695	1	molecular	molecular	ADJ
admet-3065	695	2	therapy	therapy	NOUN
admet-3065	695	3	11	11	NUM
admet-3065	695	4	(	(	PUNCT
admet-3065	695	5	2005	2005	NUM
admet-3065	695	6	)	)	PUNCT
admet-3065	695	7	801	801	NUM
admet-3065	695	8	-	-	SYM
admet-3065	695	9	810	810	NUM
admet-3065	695	10	.	.	PUNCT
admet-3065	696	1	https://doi.org/10.1016/j.ymthe.2004.12.018	https://doi.org/10.1016/j.ymthe.2004.12.018	NUM
admet-3065	696	2	[	[	X
admet-3065	696	3	74	74	NUM
admet-3065	696	4	]	]	PUNCT
admet-3065	696	5	d.	d.	PROPN
admet-3065	696	6	pozzi	pozzi	PROPN
admet-3065	696	7	,	,	PUNCT
admet-3065	696	8	c.	c.	PROPN
admet-3065	696	9	marchini	marchini	PROPN
admet-3065	696	10	,	,	PUNCT
admet-3065	696	11	f.	f.	PROPN
admet-3065	696	12	cardarelli	cardarelli	PROPN
admet-3065	696	13	,	,	PUNCT
admet-3065	696	14	h.	h.	PROPN
admet-3065	696	15	amenitsch	amenitsch	PROPN
admet-3065	696	16	,	,	PUNCT
admet-3065	696	17	c.	c.	PROPN
admet-3065	696	18	garulli	garulli	PROPN
admet-3065	696	19	,	,	PUNCT
admet-3065	696	20	a.	a.	NOUN
admet-3065	696	21	bifone	bifone	PROPN
admet-3065	696	22	,	,	PUNCT
admet-3065	696	23	g.	g.	PROPN
admet-3065	696	24	caracciolo	caracciolo	PROPN
admet-3065	696	25	.	.	PUNCT
admet-3065	697	1	transfection	transfection	NOUN
admet-3065	697	2	efficiency	efficiency	NOUN
admet-3065	697	3	boost	boost	NOUN
admet-3065	697	4	of	of	ADP
admet-3065	697	5	cholesterol	cholesterol	NOUN
admet-3065	697	6	-	-	PUNCT
admet-3065	697	7	containing	contain	VERB
admet-3065	697	8	lipoplexes	lipoplexe	NOUN
admet-3065	697	9	.	.	PUNCT
admet-3065	698	1	biochimica	biochimica	PROPN
admet-3065	698	2	et	et	PROPN
admet-3065	698	3	biophysica	biophysica	PROPN
admet-3065	698	4	acta	acta	PROPN
admet-3065	698	5	biomembranes	biomembrane	VERB
admet-3065	698	6	1818	1818	NUM
admet-3065	698	7	(	(	PUNCT
admet-3065	698	8	2012	2012	NUM
admet-3065	698	9	)	)	PUNCT
admet-3065	698	10	2335	2335	NUM
admet-3065	698	11	-	-	SYM
admet-3065	698	12	2343	2343	NUM
admet-3065	698	13	.	.	PUNCT
admet-3065	699	1	https://doi.org/10.1016/j.bbamem.2012.05.017	https://doi.org/10.1016/j.bbamem.2012.05.017	NUM
admet-3065	699	2	[	[	SYM
admet-3065	699	3	75	75	NUM
admet-3065	699	4	]	]	X
admet-3065	699	5	i.s	i.s	AUX
admet-3065	699	6	.	.	PROPN
admet-3065	699	7	zuhorn	zuhorn	PROPN
admet-3065	699	8	,	,	PUNCT
admet-3065	699	9	r.	r.	PROPN
admet-3065	699	10	kalicharan	kalicharan	PROPN
admet-3065	699	11	,	,	PUNCT
admet-3065	699	12	d.	d.	PROPN
admet-3065	699	13	hoekstra	hoekstra	PROPN
admet-3065	699	14	.	.	PROPN
admet-3065	699	15	lipoplex	lipoplex	PROPN
admet-3065	699	16	-	-	PUNCT
admet-3065	699	17	mediated	mediate	VERB
admet-3065	699	18	transfection	transfection	NOUN
admet-3065	699	19	of	of	ADP
admet-3065	699	20	mammalian	mammalian	ADJ
admet-3065	699	21	cells	cell	NOUN
admet-3065	699	22	occurs	occur	VERB
admet-3065	699	23	through	through	ADP
admet-3065	699	24	the	the	DET
admet-3065	699	25	cholesterol	cholesterol	NOUN
admet-3065	699	26	-	-	PUNCT
admet-3065	699	27	dependent	dependent	ADJ
admet-3065	699	28	clathrin	clathrin	NOUN
admet-3065	699	29	-	-	PUNCT
admet-3065	699	30	mediated	mediate	VERB
admet-3065	699	31	pathway	pathway	NOUN
admet-3065	699	32	of	of	ADP
admet-3065	699	33	endocytosis	endocytosis	NOUN
admet-3065	699	34	.	.	PUNCT
admet-3065	700	1	journal	journal	NOUN
admet-3065	700	2	of	of	ADP
admet-3065	700	3	biological	biological	ADJ
admet-3065	700	4	chemistry	chemistry	NOUN
admet-3065	700	5	277	277	NUM
admet-3065	700	6	(	(	PUNCT
admet-3065	700	7	2002	2002	NUM
admet-3065	700	8	)	)	PUNCT
admet-3065	700	9	18021	18021	NUM
admet-3065	700	10	-	-	SYM
admet-3065	700	11	18028	18028	NUM
admet-3065	700	12	.	.	PUNCT
admet-3065	701	1	https://doi.org/10.1074/jbc.m111257200	https://doi.org/10.1074/jbc.m111257200	X
admet-3065	702	1	https://doi.org/10.1016/0005-2736(90)90017-i	https://doi.org/10.1016/0005-2736(90)90017-i	PROPN
admet-3065	702	2	https://doi.org/10.1016/0005-2736(90)90017-i	https://doi.org/10.1016/0005-2736(90)90017-i	PROPN
admet-3065	702	3	https://doi.org/10.1615/critrevtherdrugcarriersyst.v21.i4.10	https://doi.org/10.1615/critrevtherdrugcarriersyst.v21.i4.10	VERB
admet-3065	702	4	https://doi.org/10.3390/ijms16035666	https://doi.org/10.3390/ijms16035666	VERB
admet-3065	702	5	https://doi.org/10.1097/cm9.0000000000003455	https://doi.org/10.1097/cm9.0000000000003455	PRON
admet-3065	702	6	https://doi.org/10.1021/bi00432a002	https://doi.org/10.1021/bi00432a002	PRON
admet-3065	702	7	https://doi.org/10.1016/s0005-2736(97)00187-9	https://doi.org/10.1016/s0005-2736(97)00187-9	VERB
admet-3065	702	8	https://doi.org/10.1074/jbc.270.32.18997	https://doi.org/10.1074/jbc.270.32.18997	NOUN
admet-3065	702	9	https://doi.org/10.1002/med.20090	https://doi.org/10.1002/med.20090	PROPN
admet-3065	702	10	.	.	PUNCT
admet-3065	703	1	https://doi.org/10.1016/j.bbamem.2015.06.020	https://doi.org/10.1016/j.bbamem.2015.06.020	VERB
admet-3065	703	2	https://doi.org/10.1126/science.281.5373.78	https://doi.org/10.1126/science.281.5373.78	PROPN
admet-3065	703	3	https://doi.org/10.1073/pnas.2307800120	https://doi.org/10.1073/pnas.2307800120	ADJ
admet-3065	703	4	https://doi.org/10.1021/acs.langmuir.4c05176	https://doi.org/10.1021/acs.langmuir.4c05176	NOUN
admet-3065	703	5	https://doi.org/10.1021/acs.accounts.9b00177	https://doi.org/10.1021/acs.accounts.9b00177	PRON
admet-3065	703	6	https://doi.org/10.1016/j.ymthe.2004.12.018	https://doi.org/10.1016/j.ymthe.2004.12.018	NUM
admet-3065	703	7	https://doi.org/10.1016/j.bbamem.2012.05.017	https://doi.org/10.1016/j.bbamem.2012.05.017	NUM
admet-3065	703	8	https://doi.org/10.1074/jbc.m111257200	https://doi.org/10.1074/jbc.m111257200	X
admet-3065	703	9	admet	admet	PROPN
admet-3065	703	10	&	&	CCONJ
admet-3065	703	11	dmpk	dmpk	PROPN
admet-3065	703	12	00(0	00(0	PROPN
admet-3065	703	13	)	)	PUNCT
admet-3065	703	14	(	(	PUNCT
admet-3065	703	15	2025	2025	NUM
admet-3065	703	16	)	)	PUNCT
admet-3065	703	17	3065	3065	NUM
admet-3065	703	18	liposome	liposome	NOUN
admet-3065	703	19	-	-	PUNCT
admet-3065	703	20	mediated	mediate	VERB
admet-3065	703	21	gene	gene	NOUN
admet-3065	703	22	delivery	delivery	NOUN
admet-3065	703	23	doi	doi	NOUN
admet-3065	703	24	:	:	PUNCT
admet-3065	703	25	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	703	26	23	23	NUM
admet-3065	704	1	[	[	X
admet-3065	704	2	76	76	NUM
admet-3065	704	3	]	]	X
admet-3065	704	4	s.	s.	PROPN
admet-3065	704	5	dokka	dokka	PROPN
admet-3065	704	6	,	,	PUNCT
admet-3065	704	7	d.	d.	PROPN
admet-3065	704	8	toledo	toledo	PROPN
admet-3065	704	9	,	,	PUNCT
admet-3065	704	10	x.	x.	PROPN
admet-3065	704	11	shi	shi	PROPN
admet-3065	704	12	,	,	PUNCT
admet-3065	704	13	v.	v.	ADP
admet-3065	704	14	castranova	castranova	PROPN
admet-3065	704	15	,	,	PUNCT
admet-3065	704	16	y.	y.	PROPN
admet-3065	704	17	rojanasakul	rojanasakul	PROPN
admet-3065	704	18	.	.	PUNCT
admet-3065	705	1	oxygen	oxygen	NOUN
admet-3065	705	2	radical	radical	ADJ
admet-3065	705	3	-	-	PUNCT
admet-3065	705	4	mediated	mediate	VERB
admet-3065	705	5	pulmonary	pulmonary	ADJ
admet-3065	705	6	toxicity	toxicity	NOUN
admet-3065	705	7	induced	induce	VERB
admet-3065	705	8	by	by	ADP
admet-3065	705	9	some	some	DET
admet-3065	705	10	cationic	cationic	ADJ
admet-3065	705	11	liposomes	liposome	NOUN
admet-3065	705	12	.	.	PUNCT
admet-3065	706	1	pharmaceutical	pharmaceutical	ADJ
admet-3065	706	2	research	research	NOUN
admet-3065	706	3	17	17	NUM
admet-3065	706	4	(	(	PUNCT
admet-3065	706	5	2000	2000	NUM
admet-3065	706	6	)	)	PUNCT
admet-3065	706	7	521	521	NUM
admet-3065	706	8	-	-	SYM
admet-3065	706	9	525	525	NUM
admet-3065	706	10	.	.	PUNCT
admet-3065	707	1	https://doi.org/10.1023/a:1007504613351	https://doi.org/10.1023/a:1007504613351	NOUN
admet-3065	708	1	[	[	X
admet-3065	708	2	77	77	NUM
admet-3065	708	3	]	]	X
admet-3065	708	4	k.	k.	PROPN
admet-3065	708	5	lappalainen	lappalainen	PROPN
admet-3065	708	6	,	,	PUNCT
admet-3065	708	7	i.	i.	PROPN
admet-3065	708	8	jääskeläinen	jääskeläinen	PROPN
admet-3065	708	9	,	,	PUNCT
admet-3065	708	10	k.	k.	PROPN
admet-3065	708	11	syrjänen	syrjänen	PROPN
admet-3065	708	12	,	,	PUNCT
admet-3065	708	13	a.	a.	NOUN
admet-3065	708	14	urtti	urtti	PROPN
admet-3065	708	15	,	,	PUNCT
admet-3065	708	16	s.	s.	PROPN
admet-3065	708	17	syrjänen	syrjänen	PROPN
admet-3065	708	18	.	.	PUNCT
admet-3065	709	1	comparison	comparison	NOUN
admet-3065	709	2	of	of	ADP
admet-3065	709	3	cell	cell	NOUN
admet-3065	709	4	proliferation	proliferation	NOUN
admet-3065	709	5	and	and	CCONJ
admet-3065	709	6	toxicity	toxicity	NOUN
admet-3065	709	7	assays	assay	NOUN
admet-3065	709	8	using	use	VERB
admet-3065	709	9	two	two	NUM
admet-3065	709	10	cationic	cationic	ADJ
admet-3065	709	11	liposomes	liposome	NOUN
admet-3065	709	12	.	.	PUNCT
admet-3065	710	1	pharmaceutical	pharmaceutical	ADJ
admet-3065	710	2	research	research	NOUN
admet-3065	710	3	11	11	NUM
admet-3065	710	4	(	(	PUNCT
admet-3065	710	5	1994	1994	NUM
admet-3065	710	6	)	)	PUNCT
admet-3065	710	7	1127	1127	NUM
admet-3065	710	8	-	-	SYM
admet-3065	710	9	1131	1131	NUM
admet-3065	710	10	.	.	PUNCT
admet-3065	711	1	https://doi.org/10.1023/a:1018932714745	https://doi.org/10.1023/a:1018932714745	VERB
admet-3065	711	2	[	[	X
admet-3065	711	3	78	78	NUM
admet-3065	711	4	]	]	PUNCT
admet-3065	711	5	c.	c.	PROPN
admet-3065	711	6	srinivasan	srinivasan	PROPN
admet-3065	711	7	,	,	PUNCT
admet-3065	711	8	d.j	d.j	PROPN
admet-3065	711	9	.	.	PROPN
admet-3065	711	10	burgess	burgess	PROPN
admet-3065	711	11	.	.	PUNCT
admet-3065	712	1	optimization	optimization	NOUN
admet-3065	712	2	and	and	CCONJ
admet-3065	712	3	characterization	characterization	NOUN
admet-3065	712	4	of	of	ADP
admet-3065	712	5	anionic	anionic	ADJ
admet-3065	712	6	lipoplexes	lipoplexe	NOUN
admet-3065	712	7	for	for	ADP
admet-3065	712	8	gene	gene	NOUN
admet-3065	712	9	delivery	delivery	NOUN
admet-3065	712	10	.	.	PUNCT
admet-3065	713	1	journal	journal	PROPN
admet-3065	713	2	of	of	ADP
admet-3065	713	3	controlled	control	VERB
admet-3065	713	4	release	release	NOUN
admet-3065	713	5	136	136	NUM
admet-3065	713	6	(	(	PUNCT
admet-3065	713	7	2009	2009	NUM
admet-3065	713	8	)	)	PUNCT
admet-3065	713	9	62	62	NUM
admet-3065	713	10	-	-	SYM
admet-3065	713	11	70	70	NUM
admet-3065	713	12	.	.	PUNCT
admet-3065	714	1	https://doi.org/10.1016/j.jconrel.2009.01.022	https://doi.org/10.1016/j.jconrel.2009.01.022	NOUN
admet-3065	714	2	[	[	X
admet-3065	714	3	79	79	NUM
admet-3065	714	4	]	]	PUNCT
admet-3065	714	5	f.	f.	PROPN
admet-3065	714	6	roerdink	roerdink	PROPN
admet-3065	714	7	,	,	PUNCT
admet-3065	714	8	n.m	n.m	PROPN
admet-3065	714	9	.	.	PROPN
admet-3065	714	10	wassef	wassef	PROPN
admet-3065	714	11	,	,	PUNCT
admet-3065	714	12	e.c	e.c	PROPN
admet-3065	714	13	.	.	PROPN
admet-3065	714	14	richardson	richardson	PROPN
admet-3065	714	15	,	,	PUNCT
admet-3065	714	16	c.r	c.r	PROPN
admet-3065	714	17	.	.	PROPN
admet-3065	714	18	alving	alve	VERB
admet-3065	714	19	.	.	PUNCT
admet-3065	715	1	effects	effect	NOUN
admet-3065	715	2	of	of	ADP
admet-3065	715	3	negatively	negatively	ADV
admet-3065	715	4	charged	charge	VERB
admet-3065	715	5	lipids	lipid	NOUN
admet-3065	715	6	on	on	ADP
admet-3065	715	7	phagocytosis	phagocytosis	NOUN
admet-3065	715	8	of	of	ADP
admet-3065	715	9	liposomes	liposome	NOUN
admet-3065	715	10	opsonized	opsonize	VERB
admet-3065	715	11	by	by	ADP
admet-3065	715	12	complement	complement	NOUN
admet-3065	715	13	.	.	PUNCT
admet-3065	716	1	bba	bba	PROPN
admet-3065	716	2	biomembranes	biomembrane	VERB
admet-3065	716	3	734	734	NUM
admet-3065	716	4	(	(	PUNCT
admet-3065	716	5	1983	1983	NUM
admet-3065	716	6	)	)	PUNCT
admet-3065	716	7	33	33	NUM
admet-3065	716	8	-	-	SYM
admet-3065	716	9	39	39	NUM
admet-3065	716	10	.	.	PUNCT
admet-3065	717	1	https://doi.org/10.1016/0005-2736(83)90071-8	https://doi.org/10.1016/0005-2736(83)90071-8	X
admet-3065	717	2	[	[	X
admet-3065	717	3	80	80	NUM
admet-3065	717	4	]	]	X
admet-3065	717	5	s.d	s.d	PROPN
admet-3065	717	6	.	.	PROPN
admet-3065	717	7	patil	patil	PROPN
admet-3065	717	8	,	,	PUNCT
admet-3065	717	9	d.g	d.g	PROPN
admet-3065	717	10	.	.	PROPN
admet-3065	717	11	rhodes	rhodes	PROPN
admet-3065	717	12	,	,	PUNCT
admet-3065	717	13	d.j	d.j	PROPN
admet-3065	717	14	.	.	PROPN
admet-3065	717	15	burgess	burgess	PROPN
admet-3065	717	16	.	.	PUNCT
admet-3065	718	1	dna	dna	PROPN
admet-3065	718	2	-	-	PUNCT
admet-3065	718	3	based	base	VERB
admet-3065	718	4	therapeutics	therapeutic	NOUN
admet-3065	718	5	and	and	CCONJ
admet-3065	718	6	dna	dna	PROPN
admet-3065	718	7	delivery	delivery	NOUN
admet-3065	718	8	systems	system	NOUN
admet-3065	718	9	:	:	PUNCT
admet-3065	718	10	a	a	DET
admet-3065	718	11	comprehensive	comprehensive	ADJ
admet-3065	718	12	review	review	NOUN
admet-3065	718	13	.	.	PUNCT
admet-3065	719	1	the	the	DET
admet-3065	719	2	aaps	aaps	PROPN
admet-3065	719	3	journal	journal	PROPN
admet-3065	719	4	7	7	NUM
admet-3065	719	5	(	(	PUNCT
admet-3065	719	6	2005	2005	NUM
admet-3065	719	7	)	)	PUNCT
admet-3065	719	8	61	61	NUM
admet-3065	719	9	-	-	SYM
admet-3065	719	10	77	77	NUM
admet-3065	719	11	.	.	PUNCT
admet-3065	720	1	https://doi.org/10.1208/aapsj070109	https://doi.org/10.1208/aapsj070109	VERB
admet-3065	720	2	[	[	X
admet-3065	720	3	81	81	NUM
admet-3065	720	4	]	]	PUNCT
admet-3065	720	5	s.	s.	PROPN
admet-3065	720	6	porte	porte	PROPN
admet-3065	720	7	,	,	PUNCT
admet-3065	720	8	v.	v.	ADP
admet-3065	720	9	vadhana	vadhana	PROPN
admet-3065	720	10	,	,	PUNCT
admet-3065	720	11	d.	d.	PROPN
admet-3065	720	12	sengupta	sengupta	PROPN
admet-3065	720	13	.	.	PUNCT
admet-3065	721	1	a	a	DET
admet-3065	721	2	molecular	molecular	ADJ
admet-3065	721	3	view	view	NOUN
admet-3065	721	4	of	of	ADP
admet-3065	721	5	lipid	lipid	ADJ
admet-3065	721	6	nanoparticles	nanoparticle	NOUN
admet-3065	721	7	:	:	PUNCT
admet-3065	721	8	insights	insight	NOUN
admet-3065	721	9	into	into	ADP
admet-3065	721	10	their	their	PRON
admet-3065	721	11	morphology	morphology	NOUN
admet-3065	721	12	and	and	CCONJ
admet-3065	721	13	structural	structural	ADJ
admet-3065	721	14	plasticity	plasticity	NOUN
admet-3065	721	15	.	.	PUNCT
admet-3065	722	1	small	small	ADJ
admet-3065	722	2	21	21	NUM
admet-3065	722	3	(	(	PUNCT
admet-3065	722	4	2025	2025	NUM
admet-3065	722	5	)	)	PUNCT
admet-3065	722	6	05404	05404	NUM
admet-3065	722	7	.	.	PUNCT
admet-3065	723	1	https://doi.org/10.1002/smll.202505404	https://doi.org/10.1002/smll.202505404	PRON
admet-3065	724	1	[	[	X
admet-3065	724	2	82	82	NUM
admet-3065	724	3	]	]	X
admet-3065	724	4	d.	d.	PROPN
admet-3065	724	5	zhi	zhi	PROPN
admet-3065	724	6	,	,	PUNCT
admet-3065	724	7	s.	s.	PROPN
admet-3065	724	8	zhang	zhang	PROPN
admet-3065	724	9	,	,	PUNCT
admet-3065	724	10	s.	s.	PROPN
admet-3065	724	11	cui	cui	PROPN
admet-3065	724	12	,	,	PUNCT
admet-3065	724	13	y.	y.	PROPN
admet-3065	724	14	zhao	zhao	PROPN
admet-3065	724	15	,	,	PUNCT
admet-3065	724	16	y.	y.	PROPN
admet-3065	724	17	wang	wang	PROPN
admet-3065	724	18	,	,	PUNCT
admet-3065	724	19	d.	d.	PROPN
admet-3065	724	20	zhao	zhao	PROPN
admet-3065	724	21	.	.	PUNCT
admet-3065	725	1	the	the	DET
admet-3065	725	2	headgroup	headgroup	NOUN
admet-3065	725	3	evolution	evolution	NOUN
admet-3065	725	4	of	of	ADP
admet-3065	725	5	cationic	cationic	ADJ
admet-3065	725	6	lipids	lipid	NOUN
admet-3065	725	7	for	for	ADP
admet-3065	725	8	gene	gene	NOUN
admet-3065	725	9	delivery	delivery	NOUN
admet-3065	725	10	.	.	PUNCT
admet-3065	726	1	bioconjugate	bioconjugate	NOUN
admet-3065	726	2	chemistry	chemistry	NOUN
admet-3065	726	3	24	24	NUM
admet-3065	726	4	(	(	PUNCT
admet-3065	726	5	2013	2013	NUM
admet-3065	726	6	)	)	PUNCT
admet-3065	726	7	487	487	NUM
admet-3065	726	8	-	-	SYM
admet-3065	726	9	519	519	NUM
admet-3065	726	10	.	.	PUNCT
admet-3065	727	1	https://doi.org/10.1021/bc300381s	https://doi.org/10.1021/bc300381s	PROPN
admet-3065	728	1	[	[	X
admet-3065	728	2	83	83	NUM
admet-3065	728	3	]	]	PUNCT
admet-3065	728	4	r.	r.	PROPN
admet-3065	728	5	koynova	koynova	PROPN
admet-3065	728	6	,	,	PUNCT
admet-3065	728	7	b.	b.	PROPN
admet-3065	728	8	tenchov	tenchov	PROPN
admet-3065	728	9	.	.	PUNCT
admet-3065	729	1	cationic	cationic	ADJ
admet-3065	729	2	lipids	lipid	NOUN
admet-3065	729	3	:	:	PUNCT
admet-3065	729	4	molecular	molecular	ADJ
admet-3065	729	5	structure/	structure/	NUM
admet-3065	729	6	transfection	transfection	NOUN
admet-3065	729	7	activity	activity	NOUN
admet-3065	729	8	relationships	relationship	NOUN
admet-3065	729	9	and	and	CCONJ
admet-3065	729	10	interactions	interaction	NOUN
admet-3065	729	11	with	with	ADP
admet-3065	729	12	biomembranes	biomembrane	NOUN
admet-3065	729	13	.	.	PUNCT
admet-3065	730	1	topics	topic	NOUN
admet-3065	730	2	in	in	ADP
admet-3065	730	3	current	current	ADJ
admet-3065	730	4	chemistry	chemistry	NOUN
admet-3065	730	5	296	296	NUM
admet-3065	730	6	(	(	PUNCT
admet-3065	730	7	2010	2010	NUM
admet-3065	730	8	)	)	PUNCT
admet-3065	730	9	51	51	NUM
admet-3065	730	10	-	-	SYM
admet-3065	730	11	93	93	NUM
admet-3065	730	12	.	.	PUNCT
admet-3065	731	1	https://doi.org/10.1007/128_2010_67	https://doi.org/10.1007/128_2010_67	X
admet-3065	731	2	[	[	X
admet-3065	731	3	84	84	NUM
admet-3065	731	4	]	]	X
admet-3065	731	5	s.a	s.a	PROPN
admet-3065	731	6	.	.	PROPN
admet-3065	731	7	buckingham	buckingham	PROPN
admet-3065	731	8	,	,	PUNCT
admet-3065	731	9	c.j	c.j	PROPN
admet-3065	731	10	.	.	PROPN
admet-3065	731	11	garvey	garvey	PROPN
admet-3065	731	12	,	,	PUNCT
admet-3065	731	13	g.g	g.g	PROPN
admet-3065	731	14	.	.	PROPN
admet-3065	731	15	warr	warr	PROPN
admet-3065	731	16	.	.	PROPN
admet-3065	731	17	effect	effect	NOUN
admet-3065	731	18	of	of	ADP
admet-3065	731	19	head	head	NOUN
admet-3065	731	20	-	-	PUNCT
admet-3065	731	21	group	group	NOUN
admet-3065	731	22	size	size	NOUN
admet-3065	731	23	on	on	ADP
admet-3065	731	24	micellization	micellization	NOUN
admet-3065	731	25	and	and	CCONJ
admet-3065	731	26	phase	phase	NOUN
admet-3065	731	27	behavior	behavior	NOUN
admet-3065	731	28	in	in	ADP
admet-3065	731	29	quaternary	quaternary	ADJ
admet-3065	731	30	ammonium	ammonium	NOUN
admet-3065	731	31	surfactant	surfactant	NOUN
admet-3065	731	32	systems	system	NOUN
admet-3065	731	33	.	.	PUNCT
admet-3065	732	1	journal	journal	PROPN
admet-3065	732	2	of	of	ADP
admet-3065	732	3	physical	physical	ADJ
admet-3065	732	4	chemistry	chemistry	NOUN
admet-3065	732	5	97	97	NUM
admet-3065	732	6	(	(	PUNCT
admet-3065	732	7	1993	1993	NUM
admet-3065	732	8	)	)	PUNCT
admet-3065	732	9	10236	10236	NUM
admet-3065	732	10	-	-	SYM
admet-3065	732	11	10244	10244	NUM
admet-3065	732	12	.	.	PUNCT
admet-3065	733	1	https://doi.org/10.1021/j100141a054	https://doi.org/10.1021/j100141a054	PROPN
admet-3065	734	1	[	[	X
admet-3065	734	2	85	85	NUM
admet-3065	734	3	]	]	X
admet-3065	734	4	w.	w.	PROPN
admet-3065	734	5	radchatawedchakoon	radchatawedchakoon	PROPN
admet-3065	734	6	,	,	PUNCT
admet-3065	734	7	c.	c.	PROPN
admet-3065	734	8	thongbamrer	thongbamrer	PROPN
admet-3065	734	9	,	,	PUNCT
admet-3065	734	10	w.	w.	PROPN
admet-3065	734	11	konbamrung	konbamrung	PROPN
admet-3065	734	12	,	,	PUNCT
admet-3065	734	13	p.	p.	PROPN
admet-3065	734	14	khattawee	khattawee	PROPN
admet-3065	734	15	,	,	PUNCT
admet-3065	734	16	u.	u.	PROPN
admet-3065	734	17	sakee	sakee	PROPN
admet-3065	734	18	,	,	PUNCT
admet-3065	734	19	w.	w.	PROPN
admet-3065	734	20	roobsoong	roobsoong	PROPN
admet-3065	734	21	,	,	PUNCT
admet-3065	734	22	j.	j.	PROPN
admet-3065	734	23	sattabongkot	sattabongkot	PROPN
admet-3065	734	24	,	,	PUNCT
admet-3065	734	25	p.	p.	PROPN
admet-3065	734	26	opanasopit	opanasopit	PROPN
admet-3065	734	27	,	,	PUNCT
admet-3065	734	28	b.e	b.e	PROPN
admet-3065	734	29	.	.	PROPN
admet-3065	734	30	yingyongnarongkul	yingyongnarongkul	PROPN
admet-3065	734	31	.	.	PUNCT
admet-3065	735	1	the	the	DET
admet-3065	735	2	effect	effect	NOUN
admet-3065	735	3	of	of	ADP
admet-3065	735	4	polar	polar	ADJ
admet-3065	735	5	headgroups	headgroup	NOUN
admet-3065	735	6	and	and	CCONJ
admet-3065	735	7	spacer	spacer	NOUN
admet-3065	735	8	length	length	NOUN
admet-3065	735	9	on	on	ADP
admet-3065	735	10	the	the	DET
admet-3065	735	11	dna	dna	PROPN
admet-3065	735	12	transfection	transfection	NOUN
admet-3065	735	13	of	of	ADP
admet-3065	735	14	cholesterol	cholesterol	NOUN
admet-3065	735	15	-	-	PUNCT
admet-3065	735	16	based	base	VERB
admet-3065	735	17	cationic	cationic	ADJ
admet-3065	735	18	lipids	lipid	NOUN
admet-3065	735	19	.	.	PUNCT
admet-3065	736	1	rsc	rsc	PROPN
admet-3065	736	2	medicinal	medicinal	ADJ
admet-3065	736	3	chemistry	chemistry	PROPN
admet-3065	736	4	11	11	NUM
admet-3065	736	5	(	(	PUNCT
admet-3065	736	6	2020	2020	NUM
admet-3065	736	7	)	)	PUNCT
admet-3065	736	8	212	212	NUM
admet-3065	736	9	-	-	SYM
admet-3065	736	10	212	212	NUM
admet-3065	736	11	.	.	PUNCT
admet-3065	737	1	https://doi.org/10.1039/c9md00459a	https://doi.org/10.1039/c9md00459a	PROPN
admet-3065	737	2	[	[	X
admet-3065	737	3	86	86	NUM
admet-3065	737	4	]	]	PUNCT
admet-3065	737	5	m.	m.	NOUN
admet-3065	737	6	dittrich	dittrich	PROPN
admet-3065	737	7	,	,	PUNCT
admet-3065	737	8	m.	m.	PROPN
admet-3065	737	9	heinze	heinze	PROPN
admet-3065	737	10	,	,	PUNCT
admet-3065	737	11	c.	c.	PROPN
admet-3065	737	12	wölk	wölk	PROPN
admet-3065	737	13	,	,	PUNCT
admet-3065	737	14	s.s	s.s	PROPN
admet-3065	737	15	.	.	PROPN
admet-3065	737	16	funari	funari	PROPN
admet-3065	737	17	,	,	PUNCT
admet-3065	737	18	b.	b.	PROPN
admet-3065	737	19	dobner	dobner	PROPN
admet-3065	737	20	,	,	PUNCT
admet-3065	737	21	h.	h.	PROPN
admet-3065	737	22	möhwald	möhwald	PROPN
admet-3065	737	23	,	,	PUNCT
admet-3065	737	24	g.	g.	PROPN
admet-3065	737	25	brezesinski	brezesinski	PROPN
admet-3065	737	26	.	.	PUNCT
admet-3065	738	1	structurefunction	structurefunction	NOUN
admet-3065	738	2	relationships	relationship	NOUN
admet-3065	738	3	of	of	ADP
admet-3065	738	4	new	new	ADJ
admet-3065	738	5	lipids	lipid	NOUN
admet-3065	738	6	designed	design	VERB
admet-3065	738	7	for	for	ADP
admet-3065	738	8	dna	dna	PROPN
admet-3065	738	9	transfection	transfection	NOUN
admet-3065	738	10	.	.	PUNCT
admet-3065	739	1	chemphyschem	chemphyschem	NOUN
admet-3065	739	2	12	12	NUM
admet-3065	739	3	(	(	PUNCT
admet-3065	739	4	2011	2011	NUM
admet-3065	739	5	)	)	PUNCT
admet-3065	739	6	23282337	23282337	NUM
admet-3065	739	7	.	.	PUNCT
admet-3065	740	1	https://doi.org/10.1002/cphc.201100065	https://doi.org/10.1002/cphc.201100065	NOUN
admet-3065	741	1	[	[	X
admet-3065	741	2	87	87	NUM
admet-3065	741	3	]	]	X
admet-3065	741	4	e.f	e.f	PROPN
admet-3065	741	5	.	.	PROPN
admet-3065	741	6	palermo	palermo	PROPN
admet-3065	741	7	,	,	PUNCT
admet-3065	741	8	d.k	d.k	PROPN
admet-3065	741	9	.	.	PROPN
admet-3065	741	10	lee	lee	PROPN
admet-3065	741	11	,	,	PUNCT
admet-3065	741	12	a.	a.	PROPN
admet-3065	741	13	ramamoorthy	ramamoorthy	PROPN
admet-3065	741	14	,	,	PUNCT
admet-3065	741	15	k.	k.	PROPN
admet-3065	741	16	kuroda	kuroda	PROPN
admet-3065	741	17	.	.	PUNCT
admet-3065	742	1	role	role	NOUN
admet-3065	742	2	of	of	ADP
admet-3065	742	3	cationic	cationic	ADJ
admet-3065	742	4	group	group	NOUN
admet-3065	742	5	structure	structure	NOUN
admet-3065	742	6	in	in	ADP
admet-3065	742	7	membrane	membrane	NOUN
admet-3065	742	8	binding	binding	NOUN
admet-3065	742	9	and	and	CCONJ
admet-3065	742	10	disruption	disruption	NOUN
admet-3065	742	11	by	by	ADP
admet-3065	742	12	amphiphilic	amphiphilic	ADJ
admet-3065	742	13	copolymers	copolymer	NOUN
admet-3065	742	14	.	.	PUNCT
admet-3065	743	1	the	the	DET
admet-3065	743	2	journal	journal	NOUN
admet-3065	743	3	of	of	ADP
admet-3065	743	4	physical	physical	ADJ
admet-3065	743	5	chemistry	chemistry	NOUN
admet-3065	743	6	b	b	PROPN
admet-3065	743	7	115	115	NUM
admet-3065	743	8	(	(	PUNCT
admet-3065	743	9	2011	2011	NUM
admet-3065	743	10	)	)	PUNCT
admet-3065	743	11	366	366	NUM
admet-3065	743	12	-	-	SYM
admet-3065	743	13	375	375	NUM
admet-3065	743	14	.	.	PUNCT
admet-3065	743	15	https://doi.org/10.1021/jp1083357	https://doi.org/10.1021/jp1083357	PROPN
admet-3065	744	1	[	[	X
admet-3065	744	2	88	88	NUM
admet-3065	744	3	]	]	X
admet-3065	744	4	t.j	t.j	PROPN
admet-3065	744	5	.	.	PROPN
admet-3065	744	6	thomas	thomas	PROPN
admet-3065	744	7	,	,	PUNCT
admet-3065	744	8	h.a	h.a	PROPN
admet-3065	744	9	.	.	PROPN
admet-3065	744	10	tajmir	tajmir	NOUN
admet-3065	744	11	-	-	PUNCT
admet-3065	744	12	riahi	riahi	NOUN
admet-3065	744	13	,	,	PUNCT
admet-3065	744	14	t.	t.	PROPN
admet-3065	744	15	thomas	thomas	PROPN
admet-3065	744	16	.	.	PUNCT
admet-3065	745	1	polyamine	polyamine	PROPN
admet-3065	745	2	-	-	PUNCT
admet-3065	745	3	dna	dna	PROPN
admet-3065	745	4	interactions	interaction	NOUN
admet-3065	745	5	and	and	CCONJ
admet-3065	745	6	development	development	NOUN
admet-3065	745	7	of	of	ADP
admet-3065	745	8	gene	gene	NOUN
admet-3065	745	9	delivery	delivery	NOUN
admet-3065	745	10	vehicles	vehicle	NOUN
admet-3065	745	11	.	.	PUNCT
admet-3065	746	1	amino	amino	ADJ
admet-3065	746	2	acids	acid	NOUN
admet-3065	746	3	48	48	NUM
admet-3065	746	4	(	(	PUNCT
admet-3065	746	5	2016	2016	NUM
admet-3065	746	6	)	)	PUNCT
admet-3065	746	7	2423	2423	NUM
admet-3065	746	8	-	-	SYM
admet-3065	746	9	2431	2431	NUM
admet-3065	746	10	.	.	PUNCT
admet-3065	747	1	https://doi.org/10.1007/s00726-016-2246-8	https://doi.org/10.1007/s00726-016-2246-8	PUNCT
admet-3065	748	1	[	[	X
admet-3065	748	2	89	89	NUM
admet-3065	748	3	]	]	X
admet-3065	748	4	d.	d.	PROPN
admet-3065	748	5	sun	sun	PROPN
admet-3065	748	6	,	,	PUNCT
admet-3065	748	7	z.r	z.r	PROPN
admet-3065	748	8	.	.	PROPN
admet-3065	749	1	lu	lu	PROPN
admet-3065	749	2	.	.	PUNCT
admet-3065	750	1	structure	structure	NOUN
admet-3065	750	2	and	and	CCONJ
admet-3065	750	3	function	function	NOUN
admet-3065	750	4	of	of	ADP
admet-3065	750	5	cationic	cationic	ADJ
admet-3065	750	6	and	and	CCONJ
admet-3065	750	7	ionizable	ionizable	ADJ
admet-3065	750	8	lipids	lipid	NOUN
admet-3065	750	9	for	for	ADP
admet-3065	750	10	nucleic	nucleic	ADJ
admet-3065	750	11	acid	acid	NOUN
admet-3065	750	12	delivery	delivery	NOUN
admet-3065	750	13	.	.	PUNCT
admet-3065	751	1	pharmaceutical	pharmaceutical	ADJ
admet-3065	751	2	research	research	NOUN
admet-3065	751	3	40	40	NUM
admet-3065	751	4	(	(	PUNCT
admet-3065	751	5	2023	2023	NUM
admet-3065	751	6	)	)	PUNCT
admet-3065	751	7	27	27	NUM
admet-3065	751	8	.	.	PUNCT
admet-3065	751	9	https://doi.org/10.1007/s11095-022-03460-2	https://doi.org/10.1007/s11095-022-03460-2	PUNCT
admet-3065	752	1	[	[	X
admet-3065	752	2	90	90	NUM
admet-3065	752	3	]	]	X
admet-3065	752	4	p.a	p.a	PROPN
admet-3065	752	5	.	.	PROPN
admet-3065	752	6	wender	wender	PROPN
admet-3065	752	7	,	,	PUNCT
admet-3065	752	8	w.c	w.c	PROPN
admet-3065	752	9	.	.	PROPN
admet-3065	752	10	galliher	galliher	PROPN
admet-3065	752	11	,	,	PUNCT
admet-3065	752	12	e.a	e.a	PROPN
admet-3065	752	13	.	.	PROPN
admet-3065	752	14	goun	goun	PROPN
admet-3065	752	15	,	,	PUNCT
admet-3065	752	16	l.r	l.r	PROPN
admet-3065	752	17	.	.	PROPN
admet-3065	752	18	jones	jones	PROPN
admet-3065	752	19	,	,	PUNCT
admet-3065	752	20	t.h	t.h	PROPN
admet-3065	752	21	.	.	PROPN
admet-3065	752	22	pillow	pillow	NOUN
admet-3065	752	23	.	.	PUNCT
admet-3065	753	1	the	the	DET
admet-3065	753	2	design	design	NOUN
admet-3065	753	3	of	of	ADP
admet-3065	753	4	guanidinium	guanidinium	NOUN
admet-3065	753	5	-	-	PUNCT
admet-3065	753	6	rich	rich	ADJ
admet-3065	753	7	transporters	transporter	NOUN
admet-3065	753	8	and	and	CCONJ
admet-3065	753	9	their	their	PRON
admet-3065	753	10	internalization	internalization	NOUN
admet-3065	753	11	mechanisms	mechanism	NOUN
admet-3065	753	12	.	.	PUNCT
admet-3065	754	1	advanced	advanced	ADJ
admet-3065	754	2	drug	drug	NOUN
admet-3065	754	3	delivery	delivery	NOUN
admet-3065	754	4	reviews	review	NOUN
admet-3065	754	5	60	60	NUM
admet-3065	754	6	(	(	PUNCT
admet-3065	754	7	2007	2007	NUM
admet-3065	754	8	)	)	PUNCT
admet-3065	754	9	452	452	NUM
admet-3065	754	10	.	.	PUNCT
admet-3065	755	1	https://doi.org/10.1016/j.addr.2007.10.016	https://doi.org/10.1016/j.addr.2007.10.016	PROPN
admet-3065	755	2	[	[	X
admet-3065	755	3	91	91	NUM
admet-3065	755	4	]	]	X
admet-3065	755	5	e.	e.	PROPN
admet-3065	755	6	wexselblatt	wexselblatt	PROPN
admet-3065	755	7	,	,	PUNCT
admet-3065	755	8	j.d	j.d	PROPN
admet-3065	755	9	.	.	PROPN
admet-3065	755	10	esko	esko	PROPN
admet-3065	755	11	,	,	PUNCT
admet-3065	755	12	y.	y.	PROPN
admet-3065	755	13	tor	tor	PROPN
admet-3065	755	14	.	.	PUNCT
admet-3065	756	1	on	on	ADP
admet-3065	756	2	guanidinium	guanidinium	NOUN
admet-3065	756	3	and	and	CCONJ
admet-3065	756	4	cellular	cellular	ADJ
admet-3065	756	5	uptake	uptake	NOUN
admet-3065	756	6	.	.	PUNCT
admet-3065	757	1	the	the	DET
admet-3065	757	2	journal	journal	NOUN
admet-3065	757	3	of	of	ADP
admet-3065	757	4	organic	organic	ADJ
admet-3065	757	5	chemistry	chemistry	NOUN
admet-3065	757	6	79	79	NUM
admet-3065	757	7	(	(	PUNCT
admet-3065	757	8	2014	2014	NUM
admet-3065	757	9	)	)	PUNCT
admet-3065	757	10	6766	6766	NUM
admet-3065	757	11	-	-	SYM
admet-3065	757	12	6774	6774	NUM
admet-3065	757	13	.	.	PUNCT
admet-3065	757	14	https://doi.org/10.1021/jo501101s	https://doi.org/10.1021/jo501101s	PUNCT
admet-3065	758	1	[	[	X
admet-3065	758	2	92	92	NUM
admet-3065	758	3	]	]	X
admet-3065	758	4	j.b	j.b	PROPN
admet-3065	758	5	.	.	PROPN
admet-3065	758	6	rothbard	rothbard	PROPN
admet-3065	758	7	,	,	PUNCT
admet-3065	758	8	t.c	t.c	PROPN
admet-3065	758	9	.	.	PROPN
admet-3065	758	10	jessop	jessop	PROPN
admet-3065	758	11	,	,	PUNCT
admet-3065	758	12	p.a	p.a	PROPN
admet-3065	758	13	.	.	PROPN
admet-3065	758	14	wender	wender	PROPN
admet-3065	758	15	.	.	PUNCT
admet-3065	759	1	adaptive	adaptive	ADJ
admet-3065	759	2	translocation	translocation	NOUN
admet-3065	759	3	:	:	PUNCT
admet-3065	759	4	the	the	DET
admet-3065	759	5	role	role	NOUN
admet-3065	759	6	of	of	ADP
admet-3065	759	7	hydrogen	hydrogen	NOUN
admet-3065	759	8	bonding	bonding	NOUN
admet-3065	759	9	and	and	CCONJ
admet-3065	759	10	membrane	membrane	NOUN
admet-3065	759	11	potential	potential	NOUN
admet-3065	759	12	in	in	ADP
admet-3065	759	13	the	the	DET
admet-3065	759	14	uptake	uptake	NOUN
admet-3065	759	15	of	of	ADP
admet-3065	759	16	guanidinium	guanidinium	NOUN
admet-3065	759	17	-	-	PUNCT
admet-3065	759	18	rich	rich	ADJ
admet-3065	759	19	transporters	transporter	NOUN
admet-3065	759	20	into	into	ADP
admet-3065	759	21	cells	cell	NOUN
admet-3065	759	22	.	.	PUNCT
admet-3065	760	1	advanced	advanced	ADJ
admet-3065	760	2	drug	drug	NOUN
admet-3065	760	3	delivery	delivery	NOUN
admet-3065	760	4	reviews	review	VERB
admet-3065	760	5	57	57	NUM
admet-3065	760	6	(	(	PUNCT
admet-3065	760	7	2005	2005	NUM
admet-3065	760	8	)	)	PUNCT
admet-3065	760	9	495	495	NUM
admet-3065	760	10	-	-	SYM
admet-3065	760	11	504	504	NUM
admet-3065	760	12	.	.	PUNCT
admet-3065	761	1	https://doi.org/10.1016/j.addr.2004.10.003	https://doi.org/10.1016/j.addr.2004.10.003	PRON
admet-3065	761	2	[	[	X
admet-3065	761	3	93	93	NUM
admet-3065	761	4	]	]	PUNCT
admet-3065	761	5	k.	k.	PROPN
admet-3065	761	6	koiwai	koiwai	PROPN
admet-3065	761	7	,	,	PUNCT
admet-3065	761	8	k.	k.	PROPN
admet-3065	761	9	tokuhisa	tokuhisa	PROPN
admet-3065	761	10	,	,	PUNCT
admet-3065	761	11	r.	r.	PROPN
admet-3065	761	12	karinaga	karinaga	PROPN
admet-3065	761	13	,	,	PUNCT
admet-3065	761	14	y.	y.	PROPN
admet-3065	761	15	kudo	kudo	PROPN
admet-3065	761	16	,	,	PUNCT
admet-3065	761	17	s.	s.	PROPN
admet-3065	761	18	kusuki	kusuki	PROPN
admet-3065	761	19	,	,	PUNCT
admet-3065	761	20	y.	y.	PROPN
admet-3065	761	21	takeda	takeda	PROPN
admet-3065	761	22	.	.	PUNCT
admet-3065	762	1	transition	transition	NOUN
admet-3065	762	2	from	from	ADP
admet-3065	762	3	a	a	DET
admet-3065	762	4	normal	normal	ADJ
admet-3065	762	5	to	to	ADP
admet-3065	762	6	inverted	inverted	ADJ
admet-3065	762	7	cylinder	cylinder	NOUN
admet-3065	762	8	for	for	ADP
admet-3065	762	9	an	an	DET
admet-3065	762	10	amidine	amidine	ADJ
admet-3065	762	11	-	-	PUNCT
admet-3065	762	12	bearing	bear	VERB
admet-3065	762	13	lipid	lipid	NOUN
admet-3065	762	14	/	/	SYM
admet-3065	762	15	pdna	pdna	PROPN
admet-3065	762	16	complex	complex	NOUN
admet-3065	762	17	and	and	CCONJ
admet-3065	762	18	its	its	PRON
admet-3065	762	19	excellent	excellent	ADJ
admet-3065	762	20	transfection	transfection	NOUN
admet-3065	762	21	.	.	PUNCT
admet-3065	763	1	bioconjugate	bioconjugate	NOUN
admet-3065	763	2	chemistry	chemistry	NOUN
admet-3065	763	3	16	16	NUM
admet-3065	763	4	(	(	PUNCT
admet-3065	763	5	2005	2005	NUM
admet-3065	763	6	)	)	PUNCT
admet-3065	763	7	1197	1197	NUM
admet-3065	763	8	-	-	SYM
admet-3065	763	9	1202	1202	NUM
admet-3065	763	10	.	.	PUNCT
admet-3065	764	1	https://doi.org/10.1021/bc050164a	https://doi.org/10.1021/bc050164a	NOUN
admet-3065	764	2	[	[	X
admet-3065	764	3	94	94	NUM
admet-3065	764	4	]	]	X
admet-3065	764	5	m.f	m.f	PROPN
admet-3065	764	6	.	.	PROPN
admet-3065	764	7	lensink	lensink	PROPN
admet-3065	764	8	,	,	PUNCT
admet-3065	764	9	c.	c.	PROPN
admet-3065	764	10	lonez	lonez	PROPN
admet-3065	764	11	,	,	PUNCT
admet-3065	764	12	j.-m	j.-m	NOUN
admet-3065	764	13	.	.	PUNCT
admet-3065	765	1	ruysschaert	ruysschaert	PROPN
admet-3065	765	2	,	,	PUNCT
admet-3065	765	3	m.	m.	NOUN
admet-3065	765	4	vandenbranden	vandenbranden	NOUN
admet-3065	765	5	.	.	PUNCT
admet-3065	766	1	characterization	characterization	NOUN
admet-3065	766	2	of	of	ADP
admet-3065	766	3	the	the	DET
admet-3065	766	4	cationic	cationic	ADJ
admet-3065	766	5	dic14	dic14	NOUN
admet-3065	766	6	-	-	PUNCT
admet-3065	766	7	amidine	amidine	ADJ
admet-3065	766	8	bilayer	bilayer	NOUN
admet-3065	766	9	by	by	ADP
admet-3065	766	10	mixed	mixed	ADJ
admet-3065	766	11	dmpc	dmpc	NOUN
admet-3065	766	12	/	/	SYM
admet-3065	766	13	dic14	dic14	NOUN
admet-3065	766	14	-	-	PUNCT
admet-3065	766	15	amidine	amidine	VERB
admet-3065	766	16	molecular	molecular	ADJ
admet-3065	766	17	dynamics	dynamic	NOUN
admet-3065	766	18	simulations	simulation	NOUN
admet-3065	766	19	shows	show	VERB
admet-3065	766	20	an	an	DET
admet-3065	766	21	https://doi.org/10.1023/a:1007504613351	https://doi.org/10.1023/a:1007504613351	NOUN
admet-3065	766	22	https://doi.org/10.1023/a:1018932714745	https://doi.org/10.1023/a:1018932714745	NOUN
admet-3065	766	23	https://doi.org/10.1016/j.jconrel.2009.01.022	https://doi.org/10.1016/j.jconrel.2009.01.022	NOUN
admet-3065	766	24	https://doi.org/10.1016/0005-2736(83)90071-8	https://doi.org/10.1016/0005-2736(83)90071-8	VERB
admet-3065	766	25	https://doi.org/10.1208/aapsj070109	https://doi.org/10.1208/aapsj070109	VERB
admet-3065	766	26	https://doi.org/10.1002/smll.202505404	https://doi.org/10.1002/smll.202505404	NOUN
admet-3065	766	27	https://doi.org/10.1021/bc300381s	https://doi.org/10.1021/bc300381s	PROPN
admet-3065	766	28	https://doi.org/10.1007/128_2010_67	https://doi.org/10.1007/128_2010_67	PROPN
admet-3065	766	29	https://doi.org/10.1021/j100141a054	https://doi.org/10.1021/j100141a054	NOUN
admet-3065	766	30	https://doi.org/10.1039/c9md00459a	https://doi.org/10.1039/c9md00459a	PROPN
admet-3065	766	31	https://doi.org/10.1002/cphc.201100065	https://doi.org/10.1002/cphc.201100065	PROPN
admet-3065	766	32	https://doi.org/10.1021/jp1083357	https://doi.org/10.1021/jp1083357	NUM
admet-3065	766	33	https://doi.org/10.1007/s00726-016-2246-8	https://doi.org/10.1007/s00726-016-2246-8	NUM
admet-3065	766	34	https://doi.org/10.1007/s11095-022-03460-2	https://doi.org/10.1007/s11095-022-03460-2	PROPN
admet-3065	766	35	https://doi.org/10.1016/j.addr.2007.10.016	https://doi.org/10.1016/j.addr.2007.10.016	PROPN
admet-3065	766	36	https://doi.org/10.1021/jo501101s	https://doi.org/10.1021/jo501101s	PROPN
admet-3065	767	1	https://doi.org/10.1016/j.addr.2004.10.003	https://doi.org/10.1016/j.addr.2004.10.003	PROPN
admet-3065	767	2	https://doi.org/10.1021/bc050164a	https://doi.org/10.1021/bc050164a	PROPN
admet-3065	767	3	e.	e.	PROPN
admet-3065	767	4	j.	j.	PROPN
admet-3065	767	5	saleh	saleh	PROPN
admet-3065	767	6	et	et	PROPN
admet-3065	767	7	al	al	PROPN
admet-3065	767	8	.	.	PROPN
admet-3065	767	9	admet	admet	PROPN
admet-3065	767	10	&	&	CCONJ
admet-3065	767	11	dmpk	dmpk	PROPN
admet-3065	767	12	00(0	00(0	PROPN
admet-3065	767	13	)	)	PUNCT
admet-3065	767	14	(	(	PUNCT
admet-3065	767	15	2025	2025	NUM
admet-3065	767	16	)	)	PUNCT
admet-3065	767	17	3065	3065	NUM
admet-3065	767	18	24	24	NUM
admet-3065	767	19	interdigitated	interdigitate	VERB
admet-3065	767	20	nonlamellar	nonlamellar	ADJ
admet-3065	767	21	bilayer	bilayer	NOUN
admet-3065	767	22	phase	phase	NOUN
admet-3065	767	23	.	.	PUNCT
admet-3065	768	1	langmuir	langmuir	PROPN
admet-3065	768	2	25	25	NUM
admet-3065	768	3	(	(	PUNCT
admet-3065	768	4	2009	2009	NUM
admet-3065	768	5	)	)	PUNCT
admet-3065	768	6	5230	5230	NUM
admet-3065	768	7	-	-	SYM
admet-3065	768	8	5238	5238	NUM
admet-3065	768	9	.	.	PUNCT
admet-3065	769	1	https://doi.org/10.1021/la804150p	https://doi.org/10.1021/la804150p	PUNCT
admet-3065	770	1	[	[	X
admet-3065	770	2	95	95	NUM
admet-3065	770	3	]	]	PUNCT
admet-3065	770	4	m.	m.	NOUN
admet-3065	770	5	frederic	frederic	PROPN
admet-3065	770	6	,	,	PUNCT
admet-3065	770	7	d.	d.	PROPN
admet-3065	770	8	scherman	scherman	PROPN
admet-3065	770	9	,	,	PUNCT
admet-3065	770	10	g.	g.	PROPN
admet-3065	770	11	byk	byk	PROPN
admet-3065	770	12	.	.	PUNCT
admet-3065	771	1	introduction	introduction	NOUN
admet-3065	771	2	of	of	ADP
admet-3065	771	3	cyclic	cyclic	ADJ
admet-3065	771	4	guanidines	guanidine	NOUN
admet-3065	771	5	into	into	ADP
admet-3065	771	6	cationic	cationic	ADJ
admet-3065	771	7	lipids	lipid	NOUN
admet-3065	771	8	for	for	ADP
admet-3065	771	9	non	non	ADJ
admet-3065	771	10	-	-	ADJ
admet-3065	771	11	viral	viral	ADJ
admet-3065	771	12	gene	gene	NOUN
admet-3065	771	13	delivery	delivery	NOUN
admet-3065	771	14	.	.	PUNCT
admet-3065	772	1	tetrahedron	tetrahedron	NOUN
admet-3065	772	2	letters	letter	NOUN
admet-3065	772	3	41	41	NUM
admet-3065	772	4	(	(	PUNCT
admet-3065	772	5	2000	2000	NUM
admet-3065	772	6	)	)	PUNCT
admet-3065	772	7	675	675	NUM
admet-3065	772	8	-	-	SYM
admet-3065	772	9	679	679	NUM
admet-3065	772	10	.	.	PUNCT
admet-3065	773	1	https://doi.org/10.1016/s00404039(99)02163-2	https://doi.org/10.1016/s00404039(99)02163-2	NOUN
admet-3065	773	2	.	.	PUNCT
admet-3065	774	1	[	[	X
admet-3065	774	2	96	96	NUM
admet-3065	774	3	]	]	X
admet-3065	774	4	j.	j.	PROPN
admet-3065	774	5	herscovici	herscovici	PROPN
admet-3065	774	6	,	,	PUNCT
admet-3065	774	7	m.j	m.j	PROPN
admet-3065	774	8	.	.	PROPN
admet-3065	774	9	egron	egron	PROPN
admet-3065	774	10	,	,	PUNCT
admet-3065	774	11	a.	a.	PROPN
admet-3065	774	12	quenot	quenot	PROPN
admet-3065	774	13	,	,	PUNCT
admet-3065	774	14	f.	f.	PROPN
admet-3065	774	15	leclercq	leclercq	PROPN
admet-3065	774	16	,	,	PUNCT
admet-3065	774	17	n.	n.	NOUN
admet-3065	774	18	leforestier	leforestier	NOUN
admet-3065	774	19	,	,	PUNCT
admet-3065	774	20	n.	n.	PROPN
admet-3065	774	21	mignet	mignet	PROPN
admet-3065	774	22	,	,	PUNCT
admet-3065	774	23	b.	b.	PROPN
admet-3065	774	24	wetzer	wetzer	PROPN
admet-3065	774	25	,	,	PUNCT
admet-3065	774	26	d.	d.	PROPN
admet-3065	774	27	scherman	scherman	PROPN
admet-3065	774	28	.	.	PUNCT
admet-3065	775	1	synthesis	synthesis	NOUN
admet-3065	775	2	of	of	ADP
admet-3065	775	3	new	new	ADJ
admet-3065	775	4	cationic	cationic	NOUN
admet-3065	775	5	lipids	lipid	NOUN
admet-3065	775	6	from	from	ADP
admet-3065	775	7	an	an	DET
admet-3065	775	8	unsaturated	unsaturated	ADJ
admet-3065	775	9	glycoside	glycoside	NOUN
admet-3065	775	10	scaffold	scaffold	NOUN
admet-3065	775	11	.	.	PUNCT
admet-3065	776	1	organic	organic	ADJ
admet-3065	776	2	letters	letter	NOUN
admet-3065	776	3	3	3	NUM
admet-3065	776	4	(	(	PUNCT
admet-3065	776	5	2001	2001	NUM
admet-3065	776	6	)	)	PUNCT
admet-3065	776	7	1893	1893	NUM
admet-3065	776	8	-	-	SYM
admet-3065	776	9	1896	1896	NUM
admet-3065	776	10	.	.	PUNCT
admet-3065	777	1	https://doi.org/10.1021/ol0159423	https://doi.org/10.1021/ol0159423	X
admet-3065	777	2	.	.	PUNCT
admet-3065	778	1	[	[	X
admet-3065	778	2	97	97	NUM
admet-3065	778	3	]	]	PUNCT
admet-3065	778	4	a.	a.	NOUN
admet-3065	778	5	santel	santel	NOUN
admet-3065	778	6	,	,	PUNCT
admet-3065	778	7	m.	m.	NOUN
admet-3065	778	8	aleku	aleku	PROPN
admet-3065	778	9	,	,	PUNCT
admet-3065	778	10	o.	o.	PROPN
admet-3065	778	11	keil	keil	PROPN
admet-3065	778	12	,	,	PUNCT
admet-3065	778	13	j.	j.	PROPN
admet-3065	778	14	endruschat	endruschat	PROPN
admet-3065	778	15	,	,	PUNCT
admet-3065	778	16	v.	v.	PROPN
admet-3065	778	17	esche	esche	PROPN
admet-3065	778	18	,	,	PUNCT
admet-3065	778	19	g.	g.	PROPN
admet-3065	778	20	fisch	fisch	PROPN
admet-3065	778	21	,	,	PUNCT
admet-3065	778	22	s.	s.	PROPN
admet-3065	778	23	dames	dames	PROPN
admet-3065	778	24	,	,	PUNCT
admet-3065	778	25	k.	k.	PROPN
admet-3065	778	26	löffler	löffler	PROPN
admet-3065	778	27	,	,	PUNCT
admet-3065	778	28	m.	m.	NOUN
admet-3065	778	29	fechtner	fechtner	PROPN
admet-3065	778	30	,	,	PUNCT
admet-3065	778	31	w.	w.	PROPN
admet-3065	778	32	arnold	arnold	PROPN
admet-3065	778	33	,	,	PUNCT
admet-3065	778	34	k.	k.	PROPN
admet-3065	778	35	giese	giese	PROPN
admet-3065	778	36	,	,	PUNCT
admet-3065	778	37	a.	a.	NOUN
admet-3065	778	38	klippel	klippel	NOUN
admet-3065	778	39	,	,	PUNCT
admet-3065	778	40	j.	j.	PROPN
admet-3065	778	41	kaufmann	kaufmann	PROPN
admet-3065	778	42	.	.	PUNCT
admet-3065	779	1	a	a	DET
admet-3065	779	2	novel	novel	ADJ
admet-3065	779	3	sirna	sirna	PROPN
admet-3065	779	4	-	-	PUNCT
admet-3065	779	5	lipoplex	lipoplex	PROPN
admet-3065	779	6	technology	technology	NOUN
admet-3065	779	7	for	for	ADP
admet-3065	779	8	rna	rna	NOUN
admet-3065	779	9	interference	interference	NOUN
admet-3065	779	10	in	in	ADP
admet-3065	779	11	the	the	DET
admet-3065	779	12	mouse	mouse	NOUN
admet-3065	779	13	vascular	vascular	ADJ
admet-3065	779	14	endothelium	endothelium	NOUN
admet-3065	779	15	.	.	PUNCT
admet-3065	780	1	gene	gene	NOUN
admet-3065	780	2	therapy	therapy	NOUN
admet-3065	780	3	13	13	NUM
admet-3065	780	4	(	(	PUNCT
admet-3065	780	5	2006	2006	NUM
admet-3065	780	6	)	)	PUNCT
admet-3065	780	7	1222	1222	NUM
admet-3065	780	8	-	-	SYM
admet-3065	780	9	1234	1234	NUM
admet-3065	780	10	.	.	PUNCT
admet-3065	781	1	https://doi.org/10.1038/sj.gt.3302777	https://doi.org/10.1038/sj.gt.3302777	NOUN
admet-3065	781	2	.	.	PUNCT
admet-3065	782	1	[	[	X
admet-3065	782	2	98	98	NUM
admet-3065	782	3	]	]	PUNCT
admet-3065	782	4	s.	s.	PROPN
admet-3065	782	5	bhattacharya	bhattacharya	PROPN
admet-3065	782	6	,	,	PUNCT
admet-3065	782	7	a.	a.	PROPN
admet-3065	782	8	bajaj	bajaj	PROPN
admet-3065	782	9	.	.	PUNCT
admet-3065	783	1	advances	advance	NOUN
admet-3065	783	2	in	in	ADP
admet-3065	783	3	gene	gene	NOUN
admet-3065	783	4	delivery	delivery	NOUN
admet-3065	783	5	through	through	ADP
admet-3065	783	6	molecular	molecular	ADJ
admet-3065	783	7	design	design	NOUN
admet-3065	783	8	of	of	ADP
admet-3065	783	9	cationic	cationic	ADJ
admet-3065	783	10	lipids	lipid	NOUN
admet-3065	783	11	.	.	PUNCT
admet-3065	784	1	advances	advance	NOUN
admet-3065	784	2	in	in	ADP
admet-3065	784	3	biochemical	biochemical	ADJ
admet-3065	784	4	engineering	engineering	NOUN
admet-3065	784	5	/	/	SYM
admet-3065	784	6	biotechnology	biotechnology	NOUN
admet-3065	784	7	117	117	NUM
admet-3065	784	8	(	(	PUNCT
admet-3065	784	9	2009	2009	NUM
admet-3065	784	10	)	)	PUNCT
admet-3065	784	11	251	251	NUM
admet-3065	784	12	-	-	SYM
admet-3065	784	13	283	283	NUM
admet-3065	784	14	.	.	PUNCT
admet-3065	785	1	https://doi.org/10.1039/b900666b	https://doi.org/10.1039/b900666b	PROPN
admet-3065	785	2	[	[	X
admet-3065	785	3	99	99	NUM
admet-3065	785	4	]	]	X
admet-3065	785	5	i.	i.	PROPN
admet-3065	785	6	van	van	PROPN
admet-3065	785	7	der	der	PROPN
admet-3065	785	8	woude	woude	PROPN
admet-3065	785	9	,	,	PUNCT
admet-3065	785	10	h.w	h.w	PROPN
admet-3065	785	11	.	.	PROPN
admet-3065	785	12	visser	visser	PROPN
admet-3065	785	13	,	,	PUNCT
admet-3065	785	14	m.b	m.b	PROPN
admet-3065	785	15	.	.	PROPN
admet-3065	785	16	ter	ter	NOUN
admet-3065	785	17	beest	beest	ADV
admet-3065	785	18	,	,	PUNCT
admet-3065	785	19	a.	a.	NOUN
admet-3065	785	20	wagenaar	wagenaar	NOUN
admet-3065	785	21	,	,	PUNCT
admet-3065	785	22	m.h	m.h	PROPN
admet-3065	785	23	.	.	PROPN
admet-3065	785	24	ruiters	ruiters	PROPN
admet-3065	785	25	,	,	PUNCT
admet-3065	785	26	j.b	j.b	PROPN
admet-3065	785	27	.	.	PROPN
admet-3065	785	28	engberts	engbert	NOUN
admet-3065	785	29	,	,	PUNCT
admet-3065	785	30	d.	d.	PROPN
admet-3065	785	31	hoekstra	hoekstra	PROPN
admet-3065	785	32	.	.	PUNCT
admet-3065	786	1	parameters	parameter	NOUN
admet-3065	786	2	influencing	influence	VERB
admet-3065	786	3	the	the	DET
admet-3065	786	4	introduction	introduction	NOUN
admet-3065	786	5	of	of	ADP
admet-3065	786	6	plasmid	plasmid	ADJ
admet-3065	786	7	dna	dna	PROPN
admet-3065	786	8	into	into	ADP
admet-3065	786	9	cells	cell	NOUN
admet-3065	786	10	by	by	ADP
admet-3065	786	11	the	the	DET
admet-3065	786	12	use	use	NOUN
admet-3065	786	13	of	of	ADP
admet-3065	786	14	synthetic	synthetic	ADJ
admet-3065	786	15	amphiphiles	amphiphile	NOUN
admet-3065	786	16	as	as	ADP
admet-3065	786	17	a	a	DET
admet-3065	786	18	carrier	carrier	NOUN
admet-3065	786	19	system	system	NOUN
admet-3065	786	20	.	.	PUNCT
admet-3065	787	1	biochimica	biochimica	PROPN
admet-3065	787	2	et	et	PROPN
admet-3065	787	3	biophysica	biophysica	PROPN
admet-3065	787	4	acta	acta	PROPN
admet-3065	787	5	-	-	PUNCT
admet-3065	787	6	biomembranes	biomembranes	PROPN
admet-3065	787	7	1240	1240	NUM
admet-3065	787	8	(	(	PUNCT
admet-3065	787	9	1995	1995	NUM
admet-3065	787	10	)	)	PUNCT
admet-3065	787	11	34	34	NUM
admet-3065	787	12	-	-	SYM
admet-3065	787	13	40	40	NUM
admet-3065	787	14	.	.	PUNCT
admet-3065	788	1	https://doi.org/10.1016/0005-2736(95)00161-1	https://doi.org/10.1016/0005-2736(95)00161-1	VERB
admet-3065	788	2	[	[	X
admet-3065	788	3	100	100	NUM
admet-3065	788	4	]	]	PUNCT
admet-3065	788	5	b.	b.	PROPN
admet-3065	788	6	martin	martin	PROPN
admet-3065	788	7	,	,	PUNCT
admet-3065	788	8	m.	m.	NOUN
admet-3065	788	9	sainlos	sainlo	NOUN
admet-3065	788	10	,	,	PUNCT
admet-3065	788	11	a.	a.	NOUN
admet-3065	788	12	aissaoui	aissaoui	PROPN
admet-3065	788	13	,	,	PUNCT
admet-3065	788	14	n.	n.	PROPN
admet-3065	788	15	oudrhiri	oudrhiri	PROPN
admet-3065	788	16	,	,	PUNCT
admet-3065	788	17	m.	m.	NOUN
admet-3065	788	18	hauchecorne	hauchecorne	PROPN
admet-3065	788	19	,	,	PUNCT
admet-3065	788	20	j.p	j.p	PROPN
admet-3065	788	21	.	.	PROPN
admet-3065	788	22	vigneron	vigneron	PROPN
admet-3065	788	23	,	,	PUNCT
admet-3065	788	24	j.m	j.m	PROPN
admet-3065	788	25	.	.	PROPN
admet-3065	788	26	lehn	lehn	PROPN
admet-3065	788	27	,	,	PUNCT
admet-3065	788	28	p.	p.	PROPN
admet-3065	788	29	lehn	lehn	PROPN
admet-3065	788	30	.	.	PUNCT
admet-3065	789	1	the	the	DET
admet-3065	789	2	design	design	NOUN
admet-3065	789	3	of	of	ADP
admet-3065	789	4	cationic	cationic	ADJ
admet-3065	789	5	lipids	lipid	NOUN
admet-3065	789	6	for	for	ADP
admet-3065	789	7	gene	gene	NOUN
admet-3065	789	8	delivery	delivery	NOUN
admet-3065	789	9	.	.	PUNCT
admet-3065	790	1	current	current	ADJ
admet-3065	790	2	pharmaceutical	pharmaceutical	ADJ
admet-3065	790	3	design	design	NOUN
admet-3065	790	4	11	11	NUM
admet-3065	790	5	(	(	PUNCT
admet-3065	790	6	2005	2005	NUM
admet-3065	790	7	)	)	PUNCT
admet-3065	790	8	375	375	NUM
admet-3065	790	9	-	-	SYM
admet-3065	790	10	394	394	NUM
admet-3065	790	11	.	.	PUNCT
admet-3065	790	12	https://doi.org/10.2174/1381612053382133	https://doi.org/10.2174/1381612053382133	X
admet-3065	791	1	[	[	X
admet-3065	791	2	101	101	NUM
admet-3065	791	3	]	]	PUNCT
admet-3065	791	4	t.	t.	PROPN
admet-3065	791	5	ren	ren	PROPN
admet-3065	791	6	,	,	PUNCT
admet-3065	791	7	y.k	y.k	PROPN
admet-3065	791	8	.	.	PROPN
admet-3065	791	9	song	song	PROPN
admet-3065	791	10	,	,	PUNCT
admet-3065	791	11	g.	g.	PROPN
admet-3065	791	12	zhang	zhang	PROPN
admet-3065	791	13	,	,	PUNCT
admet-3065	791	14	d.	d.	PROPN
admet-3065	791	15	liu	liu	PROPN
admet-3065	791	16	.	.	PUNCT
admet-3065	792	1	structural	structural	ADJ
admet-3065	792	2	basis	basis	NOUN
admet-3065	792	3	of	of	ADP
admet-3065	792	4	dotma	dotma	NOUN
admet-3065	792	5	for	for	ADP
admet-3065	792	6	effective	effective	ADJ
admet-3065	792	7	gene	gene	NOUN
admet-3065	792	8	delivery	delivery	NOUN
admet-3065	792	9	.	.	PUNCT
admet-3065	793	1	bioconjugate	bioconjugate	NOUN
admet-3065	793	2	chemistry	chemistry	NOUN
admet-3065	793	3	11	11	NUM
admet-3065	793	4	(	(	PUNCT
admet-3065	793	5	2000	2000	NUM
admet-3065	793	6	)	)	PUNCT
admet-3065	793	7	452	452	NUM
admet-3065	793	8	-	-	SYM
admet-3065	793	9	459	459	NUM
admet-3065	793	10	.	.	PUNCT
admet-3065	794	1	https://doi.org/10.1038/sj.gt.3301153	https://doi.org/10.1038/sj.gt.3301153	VERB
admet-3065	795	1	[	[	X
admet-3065	795	2	102	102	NUM
admet-3065	795	3	]	]	X
admet-3065	795	4	b.k	b.k	PROPN
admet-3065	795	5	.	.	PUNCT
admet-3065	795	6	kim	kim	PROPN
admet-3065	795	7	,	,	PUNCT
admet-3065	795	8	k.o	k.o	PROPN
admet-3065	795	9	.	.	PROPN
admet-3065	795	10	doh	doh	PROPN
admet-3065	795	11	,	,	PUNCT
admet-3065	795	12	j.h	j.h	PROPN
admet-3065	795	13	.	.	PROPN
admet-3065	795	14	nam	nam	PROPN
admet-3065	795	15	,	,	PUNCT
admet-3065	795	16	h.	h.	PROPN
admet-3065	795	17	kang	kang	PROPN
admet-3065	795	18	,	,	PUNCT
admet-3065	795	19	j.g	j.g	PROPN
admet-3065	795	20	.	.	PROPN
admet-3065	795	21	park	park	PROPN
admet-3065	795	22	,	,	PUNCT
admet-3065	795	23	i.j	i.j	PROPN
admet-3065	795	24	.	.	PROPN
admet-3065	795	25	moon	moon	PROPN
admet-3065	795	26	,	,	PUNCT
admet-3065	795	27	y.b	y.b	PROPN
admet-3065	795	28	.	.	PROPN
admet-3065	795	29	seu	seu	PROPN
admet-3065	795	30	.	.	PUNCT
admet-3065	796	1	synthesis	synthesis	NOUN
admet-3065	796	2	of	of	ADP
admet-3065	796	3	novel	novel	ADJ
admet-3065	796	4	cholesterolbased	cholesterolbase	VERB
admet-3065	796	5	cationic	cationic	NOUN
admet-3065	796	6	lipids	lipid	NOUN
admet-3065	796	7	for	for	ADP
admet-3065	796	8	gene	gene	NOUN
admet-3065	796	9	delivery	delivery	NOUN
admet-3065	796	10	.	.	PUNCT
admet-3065	797	1	bioorganic	bioorganic	PROPN
admet-3065	797	2	&	&	CCONJ
admet-3065	797	3	medicinal	medicinal	ADJ
admet-3065	797	4	chemistry	chemistry	NOUN
admet-3065	797	5	letters	letter	NOUN
admet-3065	797	6	19	19	NUM
admet-3065	797	7	(	(	PUNCT
admet-3065	797	8	2009	2009	NUM
admet-3065	797	9	)	)	PUNCT
admet-3065	797	10	29862989	29862989	NUM
admet-3065	797	11	.	.	PUNCT
admet-3065	798	1	https://doi.org/10.1016/j.bmcl.2009.04.036	https://doi.org/10.1016/j.bmcl.2009.04.036	NOUN
admet-3065	799	1	[	[	X
admet-3065	799	2	103	103	NUM
admet-3065	799	3	]	]	X
admet-3065	799	4	y.k	y.k	PROPN
admet-3065	799	5	.	.	PROPN
admet-3065	799	6	ghosh	ghosh	PROPN
admet-3065	799	7	,	,	PUNCT
admet-3065	799	8	s.s	s.s	PROPN
admet-3065	799	9	.	.	PROPN
admet-3065	799	10	visweswariah	visweswariah	PROPN
admet-3065	799	11	,	,	PUNCT
admet-3065	799	12	s.	s.	PROPN
admet-3065	799	13	bhattacharya	bhattacharya	PROPN
admet-3065	799	14	.	.	PUNCT
admet-3065	800	1	nature	nature	NOUN
admet-3065	800	2	of	of	ADP
admet-3065	800	3	linkage	linkage	NOUN
admet-3065	800	4	between	between	ADP
admet-3065	800	5	the	the	DET
admet-3065	800	6	cationic	cationic	ADJ
admet-3065	800	7	headgroup	headgroup	NOUN
admet-3065	800	8	and	and	CCONJ
admet-3065	800	9	cholesteryl	cholesteryl	PROPN
admet-3065	800	10	skeleton	skeleton	PROPN
admet-3065	800	11	controls	control	VERB
admet-3065	800	12	gene	gene	NOUN
admet-3065	800	13	transfection	transfection	NOUN
admet-3065	800	14	efficiency	efficiency	NOUN
admet-3065	800	15	.	.	PUNCT
admet-3065	801	1	febs	febs	NOUN
admet-3065	801	2	letters	letter	NOUN
admet-3065	801	3	473	473	NUM
admet-3065	801	4	(	(	PUNCT
admet-3065	801	5	2000	2000	NUM
admet-3065	801	6	)	)	PUNCT
admet-3065	801	7	341	341	NUM
admet-3065	801	8	-	-	SYM
admet-3065	801	9	344	344	NUM
admet-3065	801	10	.	.	PUNCT
admet-3065	802	1	https://doi.org/10.1016/s0014-5793(00)01558-1	https://doi.org/10.1016/s0014-5793(00)01558-1	NOUN
admet-3065	803	1	[	[	X
admet-3065	803	2	104	104	NUM
admet-3065	803	3	]	]	X
admet-3065	803	4	g.	g.	PROPN
admet-3065	803	5	puras	puras	PROPN
admet-3065	803	6	,	,	PUNCT
admet-3065	803	7	m.	m.	NOUN
admet-3065	803	8	mashal	mashal	PROPN
admet-3065	803	9	,	,	PUNCT
admet-3065	803	10	j.	j.	PROPN
admet-3065	803	11	zárate	zárate	PROPN
admet-3065	803	12	,	,	PUNCT
admet-3065	803	13	m.	m.	NOUN
admet-3065	803	14	agirre	agirre	PROPN
admet-3065	803	15	,	,	PUNCT
admet-3065	803	16	e.	e.	PROPN
admet-3065	803	17	ojeda	ojeda	PROPN
admet-3065	803	18	,	,	PUNCT
admet-3065	803	19	s.	s.	PROPN
admet-3065	803	20	grijalvo	grijalvo	PROPN
admet-3065	803	21	,	,	PUNCT
admet-3065	803	22	r.	r.	PROPN
admet-3065	803	23	eritja	eritja	PROPN
admet-3065	803	24	,	,	PUNCT
admet-3065	803	25	a.	a.	PROPN
admet-3065	803	26	diaz	diaz	PROPN
admet-3065	803	27	-	-	PUNCT
admet-3065	803	28	tahoces	tahoce	NOUN
admet-3065	803	29	,	,	PUNCT
admet-3065	803	30	g.	g.	PROPN
admet-3065	803	31	martínez	martínez	PROPN
admet-3065	803	32	navarrete	navarrete	PROPN
admet-3065	803	33	,	,	PUNCT
admet-3065	803	34	m.	m.	NOUN
admet-3065	803	35	avilés	avilés	PROPN
admet-3065	803	36	-	-	PUNCT
admet-3065	803	37	trigueros	trigueros	PROPN
admet-3065	803	38	,	,	PUNCT
admet-3065	803	39	e.	e.	PROPN
admet-3065	803	40	fernández	fernández	PROPN
admet-3065	803	41	,	,	PUNCT
admet-3065	803	42	j.l	j.l	PROPN
admet-3065	803	43	.	.	PROPN
admet-3065	803	44	pedraz	pedraz	PROPN
admet-3065	803	45	.	.	PUNCT
admet-3065	804	1	a	a	DET
admet-3065	804	2	novel	novel	ADJ
admet-3065	804	3	cationic	cationic	ADJ
admet-3065	804	4	niosome	niosome	NOUN
admet-3065	804	5	formulation	formulation	NOUN
admet-3065	804	6	for	for	ADP
admet-3065	804	7	gene	gene	NOUN
admet-3065	804	8	delivery	delivery	NOUN
admet-3065	804	9	to	to	ADP
admet-3065	804	10	the	the	DET
admet-3065	804	11	retina	retina	NOUN
admet-3065	804	12	.	.	PUNCT
admet-3065	805	1	journal	journal	PROPN
admet-3065	805	2	of	of	ADP
admet-3065	805	3	controlled	control	VERB
admet-3065	805	4	release	release	NOUN
admet-3065	805	5	174	174	NUM
admet-3065	805	6	(	(	PUNCT
admet-3065	805	7	2014	2014	NUM
admet-3065	805	8	)	)	PUNCT
admet-3065	805	9	27	27	NUM
admet-3065	805	10	-	-	SYM
admet-3065	805	11	36	36	NUM
admet-3065	805	12	.	.	PUNCT
admet-3065	806	1	https://doi.org/10.1016/j.jconrel.2013.11.004	https://doi.org/10.1016/j.jconrel.2013.11.004	PRON
admet-3065	806	2	[	[	X
admet-3065	806	3	105	105	NUM
admet-3065	806	4	]	]	X
admet-3065	806	5	l.	l.	PROPN
admet-3065	806	6	stamatatos	stamatatos	PROPN
admet-3065	806	7	,	,	PUNCT
admet-3065	806	8	r.	r.	PROPN
admet-3065	806	9	leventis	leventis	PROPN
admet-3065	806	10	,	,	PUNCT
admet-3065	806	11	m.j	m.j	PROPN
admet-3065	806	12	.	.	PROPN
admet-3065	806	13	zuckermann	zuckermann	PROPN
admet-3065	806	14	,	,	PUNCT
admet-3065	806	15	j.r	j.r	PROPN
admet-3065	806	16	.	.	PROPN
admet-3065	806	17	silvius	silvius	PROPN
admet-3065	806	18	.	.	PUNCT
admet-3065	807	1	interactions	interaction	NOUN
admet-3065	807	2	of	of	ADP
admet-3065	807	3	cationic	cationic	ADJ
admet-3065	807	4	lipid	lipid	NOUN
admet-3065	807	5	vesicles	vesicle	NOUN
admet-3065	807	6	with	with	ADP
admet-3065	807	7	negatively	negatively	ADV
admet-3065	807	8	charged	charge	VERB
admet-3065	807	9	phospholipid	phospholipid	NOUN
admet-3065	807	10	vesicles	vesicle	NOUN
admet-3065	807	11	and	and	CCONJ
admet-3065	807	12	biological	biological	ADJ
admet-3065	807	13	membranes	membrane	NOUN
admet-3065	807	14	.	.	PUNCT
admet-3065	808	1	biochemistry	biochemistry	NOUN
admet-3065	808	2	27	27	NUM
admet-3065	808	3	(	(	PUNCT
admet-3065	808	4	1988	1988	NUM
admet-3065	808	5	)	)	PUNCT
admet-3065	808	6	39173925	39173925	NUM
admet-3065	808	7	.	.	PUNCT
admet-3065	809	1	https://doi.org/10.1021/bi00411a005	https://doi.org/10.1021/bi00411a005	PROPN
admet-3065	809	2	[	[	X
admet-3065	809	3	106	106	X
admet-3065	809	4	]	]	X
admet-3065	809	5	s.	s.	PROPN
admet-3065	809	6	fletcher	fletcher	PROPN
admet-3065	809	7	,	,	PUNCT
admet-3065	809	8	a.	a.	PROPN
admet-3065	809	9	ahmad	ahmad	PROPN
admet-3065	809	10	,	,	PUNCT
admet-3065	809	11	e.	e.	PROPN
admet-3065	809	12	perouzel	perouzel	PROPN
admet-3065	809	13	,	,	PUNCT
admet-3065	809	14	a.	a.	PROPN
admet-3065	809	15	heron	heron	PROPN
admet-3065	809	16	,	,	PUNCT
admet-3065	809	17	a.d	a.d	PROPN
admet-3065	809	18	.	.	PROPN
admet-3065	809	19	miller	miller	PROPN
admet-3065	809	20	,	,	PUNCT
admet-3065	809	21	m.r	m.r	PROPN
admet-3065	809	22	.	.	PROPN
admet-3065	809	23	jorgensen	jorgensen	PROPN
admet-3065	809	24	.	.	PUNCT
admet-3065	810	1	in	in	ADP
admet-3065	810	2	vivo	vivo	ADJ
admet-3065	810	3	studies	study	NOUN
admet-3065	810	4	of	of	ADP
admet-3065	810	5	dialkynoyl	dialkynoyl	ADJ
admet-3065	810	6	analogues	analogue	NOUN
admet-3065	810	7	of	of	ADP
admet-3065	810	8	dotap	dotap	NOUN
admet-3065	810	9	demonstrate	demonstrate	VERB
admet-3065	810	10	improved	improved	ADJ
admet-3065	810	11	gene	gene	NOUN
admet-3065	810	12	transfer	transfer	NOUN
admet-3065	810	13	efficiency	efficiency	NOUN
admet-3065	810	14	of	of	ADP
admet-3065	810	15	cationic	cationic	ADJ
admet-3065	810	16	liposomes	liposome	NOUN
admet-3065	810	17	in	in	ADP
admet-3065	810	18	mouse	mouse	NOUN
admet-3065	810	19	lung	lung	PROPN
admet-3065	810	20	.	.	PUNCT
admet-3065	811	1	journal	journal	PROPN
admet-3065	811	2	of	of	ADP
admet-3065	811	3	medicinal	medicinal	ADJ
admet-3065	811	4	chemistry	chemistry	NOUN
admet-3065	811	5	49	49	NUM
admet-3065	811	6	(	(	PUNCT
admet-3065	811	7	2006	2006	NUM
admet-3065	811	8	)	)	PUNCT
admet-3065	811	9	349	349	NUM
admet-3065	811	10	-	-	SYM
admet-3065	811	11	357	357	NUM
admet-3065	811	12	.	.	PUNCT
admet-3065	812	1	https://doi.org/10.1021/jm0507227	https://doi.org/10.1021/jm0507227	X
admet-3065	813	1	[	[	X
admet-3065	813	2	107	107	NUM
admet-3065	813	3	]	]	PUNCT
admet-3065	813	4	q.	q.	PROPN
admet-3065	813	5	liu	liu	PROPN
admet-3065	813	6	,	,	PUNCT
admet-3065	813	7	w.j	w.j	PROPN
admet-3065	813	8	.	.	PROPN
admet-3065	813	9	yi	yi	PROPN
admet-3065	813	10	,	,	PUNCT
admet-3065	813	11	y.m	y.m	PROPN
admet-3065	813	12	.	.	PROPN
admet-3065	813	13	zhang	zhang	PROPN
admet-3065	813	14	,	,	PUNCT
admet-3065	813	15	j.	j.	PROPN
admet-3065	813	16	zhang	zhang	PROPN
admet-3065	813	17	,	,	PUNCT
admet-3065	813	18	l.	l.	PROPN
admet-3065	813	19	guo	guo	PROPN
admet-3065	813	20	,	,	PUNCT
admet-3065	813	21	x.q	x.q	PROPN
admet-3065	813	22	.	.	PROPN
admet-3065	813	23	yu	yu	PROPN
admet-3065	813	24	.	.	PROPN
admet-3065	813	25	biotinylated	biotinylate	VERB
admet-3065	813	26	cyclen	cyclen	NOUN
admet-3065	813	27	-	-	PUNCT
admet-3065	813	28	contained	contain	VERB
admet-3065	813	29	cationic	cationic	ADJ
admet-3065	813	30	lipids	lipid	NOUN
admet-3065	813	31	as	as	ADP
admet-3065	813	32	non	non	ADJ
admet-3065	813	33	-	-	ADJ
admet-3065	813	34	viral	viral	ADJ
admet-3065	813	35	gene	gene	NOUN
admet-3065	813	36	delivery	delivery	NOUN
admet-3065	813	37	vectors	vector	NOUN
admet-3065	813	38	.	.	PUNCT
admet-3065	814	1	chemical	chemical	NOUN
admet-3065	814	2	biology	biology	PROPN
admet-3065	814	3	&	&	CCONJ
admet-3065	814	4	drug	drug	PROPN
admet-3065	814	5	design	design	PROPN
admet-3065	814	6	82	82	NUM
admet-3065	814	7	(	(	PUNCT
admet-3065	814	8	2013	2013	NUM
admet-3065	814	9	)	)	PUNCT
admet-3065	814	10	376	376	NUM
admet-3065	814	11	-	-	SYM
admet-3065	814	12	383	383	NUM
admet-3065	814	13	.	.	PUNCT
admet-3065	815	1	https://doi.org/10.1111/cbdd.12159	https://doi.org/10.1111/cbdd.12159	PUNCT
admet-3065	816	1	[	[	X
admet-3065	816	2	108	108	NUM
admet-3065	816	3	]	]	PUNCT
admet-3065	816	4	l.	l.	PROPN
admet-3065	816	5	jin	jin	PROPN
admet-3065	816	6	,	,	PUNCT
admet-3065	816	7	x.	x.	PROPN
admet-3065	816	8	zeng	zeng	PROPN
admet-3065	816	9	,	,	PUNCT
admet-3065	816	10	m.	m.	PROPN
admet-3065	816	11	liu	liu	PROPN
admet-3065	816	12	,	,	PUNCT
admet-3065	816	13	y.	y.	PROPN
admet-3065	816	14	deng	deng	PROPN
admet-3065	816	15	,	,	PUNCT
admet-3065	816	16	n.	n.	PROPN
admet-3065	816	17	he	he	PRON
admet-3065	816	18	.	.	PUNCT
admet-3065	817	1	current	current	ADJ
admet-3065	817	2	progress	progress	NOUN
admet-3065	817	3	in	in	ADP
admet-3065	817	4	gene	gene	NOUN
admet-3065	817	5	delivery	delivery	NOUN
admet-3065	817	6	technology	technology	NOUN
admet-3065	817	7	based	base	VERB
admet-3065	817	8	on	on	ADP
admet-3065	817	9	chemical	chemical	ADJ
admet-3065	817	10	methods	method	NOUN
admet-3065	817	11	and	and	CCONJ
admet-3065	817	12	nano	nano	NOUN
admet-3065	817	13	-	-	PUNCT
admet-3065	817	14	carriers	carrier	NOUN
admet-3065	817	15	.	.	PUNCT
admet-3065	818	1	theranostics	theranostic	NOUN
admet-3065	818	2	4	4	NUM
admet-3065	818	3	(	(	PUNCT
admet-3065	818	4	2014	2014	NUM
admet-3065	818	5	)	)	PUNCT
admet-3065	818	6	240	240	NUM
admet-3065	818	7	-	-	SYM
admet-3065	818	8	255	255	NUM
admet-3065	818	9	.	.	PUNCT
admet-3065	819	1	https://doi.org/10.7150/thno.6914	https://doi.org/10.7150/thno.6914	VERB
admet-3065	820	1	[	[	X
admet-3065	820	2	109	109	NUM
admet-3065	820	3	]	]	PUNCT
admet-3065	820	4	h.w	h.w	PROPN
admet-3065	820	5	.	.	PROPN
admet-3065	820	6	yang	yang	PROPN
admet-3065	820	7	,	,	PUNCT
admet-3065	820	8	j.w	j.w	PROPN
admet-3065	820	9	.	.	PROPN
admet-3065	820	10	yi	yi	PROPN
admet-3065	820	11	,	,	PUNCT
admet-3065	820	12	e.k	e.k	PROPN
admet-3065	820	13	.	.	PROPN
admet-3065	820	14	bang	bang	PROPN
admet-3065	820	15	,	,	PUNCT
admet-3065	820	16	e.m	e.m	PROPN
admet-3065	820	17	.	.	PROPN
admet-3065	820	18	jeon	jeon	PROPN
admet-3065	820	19	,	,	PUNCT
admet-3065	820	20	b.h	b.h	PROPN
admet-3065	820	21	.	.	PUNCT
admet-3065	820	22	kim	kim	PROPN
admet-3065	820	23	.	.	PUNCT
admet-3065	821	1	cationic	cationic	ADJ
admet-3065	821	2	nucleolipids	nucleolipid	NOUN
admet-3065	821	3	as	as	ADP
admet-3065	821	4	efficient	efficient	ADJ
admet-3065	821	5	sirna	sirna	PROPN
admet-3065	821	6	carriers	carrier	NOUN
admet-3065	821	7	.	.	PUNCT
admet-3065	822	1	organic	organic	ADJ
admet-3065	822	2	&	&	CCONJ
admet-3065	822	3	biomolecular	biomolecular	ADJ
admet-3065	822	4	chemistry	chemistry	NOUN
admet-3065	822	5	9	9	NUM
admet-3065	822	6	(	(	PUNCT
admet-3065	822	7	2010	2010	NUM
admet-3065	822	8	)	)	PUNCT
admet-3065	822	9	291	291	NUM
admet-3065	822	10	-	-	SYM
admet-3065	822	11	296	296	NUM
admet-3065	822	12	.	.	PUNCT
admet-3065	823	1	https://doi.org/10.1039/c0ob00580k	https://doi.org/10.1039/c0ob00580k	PROPN
admet-3065	823	2	https://doi.org/10.1021/la804150p	https://doi.org/10.1021/la804150p	PROPN
admet-3065	823	3	https://doi.org/10.1016/s0040-4039(99)02163-2	https://doi.org/10.1016/s0040-4039(99)02163-2	PROPN
admet-3065	823	4	https://doi.org/10.1016/s0040-4039(99)02163-2	https://doi.org/10.1016/s0040-4039(99)02163-2	PROPN
admet-3065	823	5	https://doi.org/10.1021/ol0159423	https://doi.org/10.1021/ol0159423	PROPN
admet-3065	823	6	https://doi.org/10.1038/sj.gt.3302777	https://doi.org/10.1038/sj.gt.3302777	NOUN
admet-3065	823	7	https://doi.org/10.1039/b900666b	https://doi.org/10.1039/b900666b	NOUN
admet-3065	823	8	https://doi.org/10.1016/0005-2736(95)00161-1	https://doi.org/10.1016/0005-2736(95)00161-1	PROPN
admet-3065	823	9	https://doi.org/10.2174/1381612053382133	https://doi.org/10.2174/1381612053382133	NOUN
admet-3065	823	10	https://doi.org/10.1038/sj.gt.3301153	https://doi.org/10.1038/sj.gt.3301153	VERB
admet-3065	823	11	https://doi.org/10.1016/j.bmcl.2009.04.036	https://doi.org/10.1016/j.bmcl.2009.04.036	NOUN
admet-3065	823	12	https://doi.org/10.1016/s0014-5793(00)01558-1	https://doi.org/10.1016/s0014-5793(00)01558-1	NOUN
admet-3065	823	13	https://doi.org/10.1016/j.jconrel.2013.11.004	https://doi.org/10.1016/j.jconrel.2013.11.004	NOUN
admet-3065	823	14	https://doi.org/10.1021/bi00411a005	https://doi.org/10.1021/bi00411a005	PROPN
admet-3065	823	15	https://doi.org/10.1021/jm0507227	https://doi.org/10.1021/jm0507227	PROPN
admet-3065	823	16	https://doi.org/10.1111/cbdd.12159	https://doi.org/10.1111/cbdd.12159	NOUN
admet-3065	823	17	https://doi.org/10.7150/thno.6914	https://doi.org/10.7150/thno.6914	PROPN
admet-3065	823	18	https://doi.org/10.1039/c0ob00580k	https://doi.org/10.1039/c0ob00580k	PROPN
admet-3065	823	19	admet	admet	PROPN
admet-3065	823	20	&	&	CCONJ
admet-3065	823	21	dmpk	dmpk	PROPN
admet-3065	823	22	00(0	00(0	PROPN
admet-3065	823	23	)	)	PUNCT
admet-3065	823	24	(	(	PUNCT
admet-3065	823	25	2025	2025	NUM
admet-3065	823	26	)	)	PUNCT
admet-3065	823	27	3065	3065	NUM
admet-3065	823	28	liposome	liposome	NOUN
admet-3065	823	29	-	-	PUNCT
admet-3065	823	30	mediated	mediate	VERB
admet-3065	823	31	gene	gene	NOUN
admet-3065	823	32	delivery	delivery	NOUN
admet-3065	823	33	doi	doi	NOUN
admet-3065	823	34	:	:	PUNCT
admet-3065	823	35	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	823	36	25	25	NUM
admet-3065	824	1	[	[	X
admet-3065	824	2	110	110	NUM
admet-3065	824	3	]	]	PUNCT
admet-3065	824	4	j.	j.	PROPN
admet-3065	824	5	voges	voges	PROPN
admet-3065	824	6	,	,	PUNCT
admet-3065	824	7	r.	r.	PROPN
admet-3065	824	8	reszka	reszka	PROPN
admet-3065	824	9	,	,	PUNCT
admet-3065	824	10	a.	a.	NOUN
admet-3065	824	11	gossmann	gossmann	PROPN
admet-3065	824	12	,	,	PUNCT
admet-3065	824	13	c.	c.	PROPN
admet-3065	824	14	dittmar	dittmar	PROPN
admet-3065	824	15	,	,	PUNCT
admet-3065	824	16	r.	r.	PROPN
admet-3065	824	17	richter	richter	PROPN
admet-3065	824	18	,	,	PUNCT
admet-3065	824	19	g.	g.	PROPN
admet-3065	824	20	garlip	garlip	PROPN
admet-3065	824	21	,	,	PUNCT
admet-3065	824	22	l.	l.	PROPN
admet-3065	824	23	kracht	kracht	PROPN
admet-3065	824	24	,	,	PUNCT
admet-3065	824	25	h.h	h.h	PROPN
admet-3065	824	26	.	.	PROPN
admet-3065	824	27	coenen	coenen	PROPN
admet-3065	824	28	,	,	PUNCT
admet-3065	824	29	v.	v.	PROPN
admet-3065	824	30	sturm	sturm	PROPN
admet-3065	824	31	,	,	PUNCT
admet-3065	824	32	k.	k.	PROPN
admet-3065	824	33	wienhard	wienhard	PROPN
admet-3065	824	34	,	,	PUNCT
admet-3065	824	35	w.d	w.d	PROPN
admet-3065	824	36	.	.	PROPN
admet-3065	824	37	heiss	heiss	PROPN
admet-3065	824	38	,	,	PUNCT
admet-3065	824	39	a.h	a.h	PROPN
admet-3065	824	40	.	.	PROPN
admet-3065	824	41	jacobs	jacobs	PROPN
admet-3065	824	42	.	.	PUNCT
admet-3065	825	1	imaging	imaging	NOUN
admet-3065	825	2	-	-	PUNCT
admet-3065	825	3	guided	guide	VERB
admet-3065	825	4	convection	convection	NOUN
admet-3065	825	5	-	-	PUNCT
admet-3065	825	6	enhanced	enhance	VERB
admet-3065	825	7	delivery	delivery	NOUN
admet-3065	825	8	and	and	CCONJ
admet-3065	825	9	gene	gene	NOUN
admet-3065	825	10	therapy	therapy	NOUN
admet-3065	825	11	of	of	ADP
admet-3065	825	12	glioblastoma	glioblastoma	NOUN
admet-3065	825	13	.	.	PUNCT
admet-3065	826	1	annals	annal	NOUN
admet-3065	826	2	of	of	ADP
admet-3065	826	3	neurology	neurology	NOUN
admet-3065	826	4	54	54	NUM
admet-3065	826	5	(	(	PUNCT
admet-3065	826	6	2003	2003	NUM
admet-3065	826	7	)	)	PUNCT
admet-3065	826	8	479	479	NUM
admet-3065	826	9	-	-	SYM
admet-3065	826	10	487	487	NUM
admet-3065	826	11	.	.	PUNCT
admet-3065	827	1	https://doi.org/10.1002/ana.10688	https://doi.org/10.1002/ana.10688	PROPN
admet-3065	827	2	[	[	X
admet-3065	827	3	111	111	NUM
admet-3065	827	4	]	]	PUNCT
admet-3065	827	5	n.	n.	PROPN
admet-3065	827	6	dan	dan	PROPN
admet-3065	827	7	.	.	PROPN
admet-3065	828	1	multilamellar	multilamellar	PROPN
admet-3065	828	2	structures	structure	NOUN
admet-3065	828	3	of	of	ADP
admet-3065	828	4	dna	dna	NOUN
admet-3065	828	5	complexes	complex	NOUN
admet-3065	828	6	with	with	ADP
admet-3065	828	7	cationic	cationic	ADJ
admet-3065	828	8	liposomes	liposome	NOUN
admet-3065	828	9	.	.	PUNCT
admet-3065	829	1	biophysical	biophysical	ADJ
admet-3065	829	2	journal	journal	NOUN
admet-3065	829	3	73	73	NUM
admet-3065	829	4	(	(	PUNCT
admet-3065	829	5	1997	1997	NUM
admet-3065	829	6	)	)	PUNCT
admet-3065	829	7	1842	1842	NUM
admet-3065	829	8	-	-	SYM
admet-3065	829	9	1846	1846	NUM
admet-3065	829	10	.	.	PUNCT
admet-3065	830	1	https://doi.org/10.1016/s0006-3495(97)78214-6	https://doi.org/10.1016/s0006-3495(97)78214-6	PROPN
admet-3065	831	1	[	[	X
admet-3065	831	2	112	112	NUM
admet-3065	831	3	]	]	X
admet-3065	831	4	s.r	s.r	PROPN
admet-3065	831	5	.	.	PROPN
admet-3065	831	6	paliwal	paliwal	PROPN
admet-3065	831	7	,	,	PUNCT
admet-3065	831	8	r.	r.	PROPN
admet-3065	831	9	paliwal	paliwal	PROPN
admet-3065	831	10	,	,	PUNCT
admet-3065	831	11	s.p	s.p	PROPN
admet-3065	831	12	.	.	PUNCT
admet-3065	831	13	vyas	vyas	PROPN
admet-3065	831	14	.	.	PUNCT
admet-3065	832	1	a	a	DET
admet-3065	832	2	review	review	NOUN
admet-3065	832	3	of	of	ADP
admet-3065	832	4	mechanistic	mechanistic	ADJ
admet-3065	832	5	insight	insight	NOUN
admet-3065	832	6	and	and	CCONJ
admet-3065	832	7	application	application	NOUN
admet-3065	832	8	of	of	ADP
admet-3065	832	9	ph	ph	ADJ
admet-3065	832	10	-	-	ADJ
admet-3065	832	11	sensitive	sensitive	ADJ
admet-3065	832	12	liposomes	liposome	NOUN
admet-3065	832	13	in	in	ADP
admet-3065	832	14	drug	drug	NOUN
admet-3065	832	15	delivery	delivery	NOUN
admet-3065	832	16	.	.	PUNCT
admet-3065	833	1	drug	drug	NOUN
admet-3065	833	2	delivery	delivery	NOUN
admet-3065	833	3	22	22	NUM
admet-3065	833	4	(	(	PUNCT
admet-3065	833	5	2015	2015	NUM
admet-3065	833	6	)	)	PUNCT
admet-3065	833	7	231	231	NUM
admet-3065	833	8	-	-	SYM
admet-3065	833	9	242	242	NUM
admet-3065	833	10	.	.	PUNCT
admet-3065	833	11	https://doi.org/10.3109/10717544.2014.882469	https://doi.org/10.3109/10717544.2014.882469	PUNCT
admet-3065	834	1	[	[	X
admet-3065	834	2	113	113	NUM
admet-3065	834	3	]	]	PUNCT
admet-3065	834	4	t.	t.	NOUN
admet-3065	834	5	boukhnikachvili	boukhnikachvili	NOUN
admet-3065	834	6	,	,	PUNCT
admet-3065	834	7	o.	o.	PROPN
admet-3065	834	8	aguerre	aguerre	PROPN
admet-3065	834	9	-	-	PUNCT
admet-3065	834	10	chariol	chariol	PROPN
admet-3065	834	11	,	,	PUNCT
admet-3065	834	12	m.	m.	NOUN
admet-3065	834	13	airiau	airiau	PROPN
admet-3065	834	14	,	,	PUNCT
admet-3065	834	15	s.	s.	PROPN
admet-3065	834	16	lesieur	lesieur	PROPN
admet-3065	834	17	,	,	PUNCT
admet-3065	834	18	m.	m.	NOUN
admet-3065	834	19	ollivon	ollivon	PROPN
admet-3065	834	20	,	,	PUNCT
admet-3065	834	21	j.	j.	PROPN
admet-3065	834	22	vacus	vacus	PROPN
admet-3065	834	23	.	.	PUNCT
admet-3065	835	1	structure	structure	NOUN
admet-3065	835	2	of	of	ADP
admet-3065	835	3	inserum	inserum	ADJ
admet-3065	835	4	transfecting	transfecting	PROPN
admet-3065	835	5	dna	dna	NOUN
admet-3065	835	6	-	-	PUNCT
admet-3065	835	7	cationic	cationic	ADJ
admet-3065	835	8	lipid	lipid	NOUN
admet-3065	835	9	complexes	complex	NOUN
admet-3065	835	10	.	.	PUNCT
admet-3065	836	1	febs	febs	NOUN
admet-3065	836	2	letters	letter	NOUN
admet-3065	836	3	409	409	NUM
admet-3065	836	4	(	(	PUNCT
admet-3065	836	5	1997	1997	NUM
admet-3065	836	6	)	)	PUNCT
admet-3065	836	7	188	188	NUM
admet-3065	836	8	-	-	SYM
admet-3065	836	9	194	194	NUM
admet-3065	836	10	.	.	PUNCT
admet-3065	837	1	https://doi.org/10.1016/s0014-5793(97)00505-x	https://doi.org/10.1016/s0014-5793(97)00505-x	PROPN
admet-3065	837	2	.	.	PUNCT
admet-3065	838	1	[	[	X
admet-3065	838	2	114	114	NUM
admet-3065	838	3	]	]	PUNCT
admet-3065	838	4	s.	s.	PROPN
admet-3065	838	5	zhao	zhao	PROPN
admet-3065	838	6	,	,	PUNCT
admet-3065	838	7	n.	n.	PROPN
admet-3065	838	8	yu	yu	PROPN
admet-3065	838	9	,	,	PUNCT
admet-3065	838	10	h.	h.	PROPN
admet-3065	838	11	han	han	PROPN
admet-3065	838	12	,	,	PUNCT
admet-3065	838	13	s.	s.	PROPN
admet-3065	838	14	guo	guo	PROPN
admet-3065	838	15	,	,	PUNCT
admet-3065	838	16	n.	n.	PROPN
admet-3065	838	17	murthy	murthy	PROPN
admet-3065	838	18	.	.	PUNCT
admet-3065	839	1	advances	advance	NOUN
admet-3065	839	2	in	in	ADP
admet-3065	839	3	acid	acid	NOUN
admet-3065	839	4	-	-	PUNCT
admet-3065	839	5	degradable	degradable	ADJ
admet-3065	839	6	and	and	CCONJ
admet-3065	839	7	enzyme	enzyme	NOUN
admet-3065	839	8	-	-	PUNCT
admet-3065	839	9	cleavable	cleavable	ADJ
admet-3065	839	10	linkers	linker	NOUN
admet-3065	839	11	for	for	ADP
admet-3065	839	12	drug	drug	NOUN
admet-3065	839	13	delivery	delivery	NOUN
admet-3065	839	14	.	.	PUNCT
admet-3065	840	1	current	current	ADJ
admet-3065	840	2	opinion	opinion	NOUN
admet-3065	840	3	in	in	ADP
admet-3065	840	4	chemical	chemical	ADJ
admet-3065	840	5	biology	biology	NOUN
admet-3065	840	6	84	84	NUM
admet-3065	840	7	(	(	PUNCT
admet-3065	840	8	2025	2025	NUM
admet-3065	840	9	)	)	PUNCT
admet-3065	840	10	102552	102552	NUM
admet-3065	840	11	.	.	PUNCT
admet-3065	841	1	https://doi.org/10.1016/j.cbpa.2024.102552	https://doi.org/10.1016/j.cbpa.2024.102552	PROPN
admet-3065	841	2	[	[	X
admet-3065	841	3	115	115	NUM
admet-3065	841	4	]	]	X
admet-3065	841	5	y.	y.	PROPN
admet-3065	841	6	zheng	zheng	PROPN
admet-3065	841	7	,	,	PUNCT
admet-3065	841	8	j.	j.	PROPN
admet-3065	841	9	ren	ren	PROPN
admet-3065	841	10	,	,	PUNCT
admet-3065	841	11	y.	y.	PROPN
admet-3065	841	12	wu	wu	PROPN
admet-3065	841	13	,	,	PUNCT
admet-3065	841	14	x.	x.	PROPN
admet-3065	841	15	meng	meng	PROPN
admet-3065	841	16	,	,	PUNCT
admet-3065	841	17	y.	y.	PROPN
admet-3065	841	18	zhao	zhao	PROPN
admet-3065	841	19	,	,	PUNCT
admet-3065	841	20	c.	c.	PROPN
admet-3065	841	21	wu	wu	PROPN
admet-3065	841	22	.	.	PUNCT
admet-3065	842	1	proteolytic	proteolytic	ADJ
admet-3065	842	2	unlocking	unlocking	NOUN
admet-3065	842	3	of	of	ADP
admet-3065	842	4	ultrastable	ultrastable	ADJ
admet-3065	842	5	twinacylhydrazone	twinacylhydrazone	NOUN
admet-3065	842	6	linkers	linker	NOUN
admet-3065	842	7	for	for	ADP
admet-3065	842	8	lysosomal	lysosomal	ADJ
admet-3065	842	9	acid	acid	NOUN
admet-3065	842	10	-	-	PUNCT
admet-3065	842	11	triggered	trigger	VERB
admet-3065	842	12	release	release	NOUN
admet-3065	842	13	of	of	ADP
admet-3065	842	14	anticancer	anticancer	NOUN
admet-3065	842	15	drugs	drug	NOUN
admet-3065	842	16	.	.	PUNCT
admet-3065	843	1	bioconjugate	bioconjugate	NOUN
admet-3065	843	2	chemistry	chemistry	NOUN
admet-3065	843	3	28	28	NUM
admet-3065	843	4	(	(	PUNCT
admet-3065	843	5	2017	2017	NUM
admet-3065	843	6	)	)	PUNCT
admet-3065	843	7	2620	2620	NUM
admet-3065	843	8	-	-	SYM
admet-3065	843	9	2626	2626	NUM
admet-3065	843	10	.	.	PUNCT
admet-3065	844	1	https://doi.org/10.1021/acs.bioconjchem.7b00471	https://doi.org/10.1021/acs.bioconjchem.7b00471	PRON
admet-3065	845	1	[	[	X
admet-3065	845	2	116	116	X
admet-3065	845	3	]	]	X
admet-3065	845	4	h.	h.	PROPN
admet-3065	845	5	wen	wen	PROPN
admet-3065	845	6	.	.	PUNCT
admet-3065	846	1	redox	redox	PROPN
admet-3065	846	2	sensitive	sensitive	ADJ
admet-3065	846	3	nanoparticles	nanoparticle	NOUN
admet-3065	846	4	with	with	ADP
admet-3065	846	5	disulfide	disulfide	NOUN
admet-3065	846	6	bond	bond	NOUN
admet-3065	846	7	linked	link	VERB
admet-3065	846	8	sheddable	sheddable	ADJ
admet-3065	846	9	shell	shell	NOUN
admet-3065	846	10	for	for	ADP
admet-3065	846	11	intracellular	intracellular	ADJ
admet-3065	846	12	drug	drug	NOUN
admet-3065	846	13	delivery	delivery	NOUN
admet-3065	846	14	.	.	PUNCT
admet-3065	847	1	medicinal	medicinal	ADJ
admet-3065	847	2	chemistry	chemistry	NOUN
admet-3065	847	3	4	4	NUM
admet-3065	847	4	(	(	PUNCT
admet-3065	847	5	2014	2014	NUM
admet-3065	847	6	)	)	PUNCT
admet-3065	847	7	748	748	NUM
admet-3065	847	8	-	-	SYM
admet-3065	847	9	755	755	NUM
admet-3065	847	10	.	.	PUNCT
admet-3065	848	1	https://doi.org/10.4172/2161-0444.1000225	https://doi.org/10.4172/2161-0444.1000225	PROPN
admet-3065	849	1	[	[	X
admet-3065	849	2	117	117	NUM
admet-3065	849	3	]	]	PUNCT
admet-3065	849	4	k.	k.	PROPN
admet-3065	849	5	dutta	dutta	PROPN
admet-3065	849	6	,	,	PUNCT
admet-3065	849	7	r.	r.	PROPN
admet-3065	849	8	das	das	PROPN
admet-3065	849	9	,	,	PUNCT
admet-3065	849	10	j.	j.	PROPN
admet-3065	849	11	medeiros	medeiros	PROPN
admet-3065	849	12	,	,	PUNCT
admet-3065	849	13	s.	s.	PROPN
admet-3065	849	14	thayumanavan	thayumanavan	PROPN
admet-3065	849	15	.	.	PUNCT
admet-3065	850	1	disulfide	disulfide	NOUN
admet-3065	850	2	bridging	bridging	NOUN
admet-3065	850	3	strategies	strategy	NOUN
admet-3065	850	4	in	in	ADP
admet-3065	850	5	viral	viral	ADJ
admet-3065	850	6	and	and	CCONJ
admet-3065	850	7	non	non	ADJ
admet-3065	850	8	-	-	ADJ
admet-3065	850	9	viral	viral	ADJ
admet-3065	850	10	platforms	platform	NOUN
admet-3065	850	11	for	for	ADP
admet-3065	850	12	nucleic	nucleic	ADJ
admet-3065	850	13	acid	acid	NOUN
admet-3065	850	14	delivery	delivery	NOUN
admet-3065	850	15	.	.	PUNCT
admet-3065	851	1	biochemistry	biochemistry	NOUN
admet-3065	851	2	60	60	NUM
admet-3065	851	3	(	(	PUNCT
admet-3065	851	4	2021	2021	NUM
admet-3065	851	5	)	)	PUNCT
admet-3065	851	6	966	966	NUM
admet-3065	851	7	-	-	SYM
admet-3065	851	8	966	966	NUM
admet-3065	851	9	.	.	PUNCT
admet-3065	851	10	https://doi.org/10.1021/acs.biochem.0c00860	https://doi.org/10.1021/acs.biochem.0c00860	NOUN
admet-3065	851	11	[	[	X
admet-3065	851	12	118	118	NUM
admet-3065	851	13	]	]	X
admet-3065	851	14	h.	h.	PROPN
admet-3065	851	15	hatakeyama	hatakeyama	PROPN
admet-3065	851	16	,	,	PUNCT
admet-3065	851	17	h.	h.	PROPN
admet-3065	851	18	akita	akita	PROPN
admet-3065	851	19	,	,	PUNCT
admet-3065	851	20	k.	k.	PROPN
admet-3065	851	21	kogure	kogure	PROPN
admet-3065	851	22	,	,	PUNCT
admet-3065	851	23	m.	m.	NOUN
admet-3065	851	24	oishi	oishi	PROPN
admet-3065	851	25	,	,	PUNCT
admet-3065	851	26	y.	y.	PROPN
admet-3065	851	27	nagasaki	nagasaki	PROPN
admet-3065	851	28	,	,	PUNCT
admet-3065	851	29	y.	y.	PROPN
admet-3065	851	30	kihira	kihira	PROPN
admet-3065	851	31	,	,	PUNCT
admet-3065	851	32	m.	m.	PROPN
admet-3065	851	33	ueno	ueno	PROPN
admet-3065	851	34	,	,	PUNCT
admet-3065	851	35	h.	h.	PROPN
admet-3065	851	36	kobayashi	kobayashi	PROPN
admet-3065	851	37	,	,	PUNCT
admet-3065	851	38	h.	h.	PROPN
admet-3065	851	39	kikuchi	kikuchi	PROPN
admet-3065	851	40	,	,	PUNCT
admet-3065	851	41	h.	h.	PROPN
admet-3065	851	42	harashima	harashima	PROPN
admet-3065	851	43	.	.	PUNCT
admet-3065	852	1	development	development	NOUN
admet-3065	852	2	of	of	ADP
admet-3065	852	3	a	a	DET
admet-3065	852	4	novel	novel	ADJ
admet-3065	852	5	systemic	systemic	ADJ
admet-3065	852	6	gene	gene	NOUN
admet-3065	852	7	delivery	delivery	NOUN
admet-3065	852	8	system	system	NOUN
admet-3065	852	9	for	for	ADP
admet-3065	852	10	cancer	cancer	NOUN
admet-3065	852	11	therapy	therapy	NOUN
admet-3065	852	12	with	with	ADP
admet-3065	852	13	a	a	DET
admet-3065	852	14	tumor	tumor	NOUN
admet-3065	852	15	-	-	PUNCT
admet-3065	852	16	specific	specific	ADJ
admet-3065	852	17	cleavable	cleavable	ADJ
admet-3065	852	18	peg	peg	NOUN
admet-3065	852	19	-	-	PUNCT
admet-3065	852	20	lipid	lipid	NOUN
admet-3065	852	21	.	.	PUNCT
admet-3065	853	1	gene	gene	NOUN
admet-3065	853	2	therapy	therapy	NOUN
admet-3065	853	3	14	14	NUM
admet-3065	853	4	(	(	PUNCT
admet-3065	853	5	2007	2007	NUM
admet-3065	853	6	)	)	PUNCT
admet-3065	853	7	68	68	NUM
admet-3065	853	8	-	-	SYM
admet-3065	853	9	77	77	NUM
admet-3065	853	10	.	.	PUNCT
admet-3065	854	1	https://doi.org/10.1038/sj.gt.3302843	https://doi.org/10.1038/sj.gt.3302843	PROPN
admet-3065	855	1	[	[	X
admet-3065	855	2	119	119	NUM
admet-3065	855	3	]	]	X
admet-3065	855	4	o.	o.	PROPN
admet-3065	855	5	david	david	PROPN
admet-3065	855	6	,	,	PUNCT
admet-3065	855	7	v.	v.	ADP
admet-3065	855	8	diwadkar	diwadkar	NOUN
admet-3065	855	9	.	.	PUNCT
admet-3065	856	1	stimuli	stimuli	VERB
admet-3065	856	2	-	-	PUNCT
admet-3065	856	3	responsive	responsive	ADJ
admet-3065	856	4	gene	gene	NOUN
admet-3065	856	5	delivery	delivery	NOUN
admet-3065	856	6	vectors	vector	NOUN
admet-3065	856	7	.	.	PUNCT
admet-3065	857	1	current	current	ADJ
admet-3065	857	2	opinion	opinion	NOUN
admet-3065	857	3	in	in	ADP
admet-3065	857	4	molecular	molecular	ADJ
admet-3065	857	5	therapeutics	therapeutic	NOUN
admet-3065	857	6	5	5	NUM
admet-3065	857	7	(	(	PUNCT
admet-3065	857	8	2003	2003	NUM
admet-3065	857	9	)	)	PUNCT
admet-3065	857	10	345	345	NUM
admet-3065	857	11	-	-	SYM
admet-3065	857	12	350	350	NUM
admet-3065	857	13	.	.	PUNCT
admet-3065	858	1	https://doi.org/14513676	https://doi.org/14513676	X
admet-3065	859	1	[	[	X
admet-3065	859	2	120	120	NUM
admet-3065	859	3	]	]	X
admet-3065	859	4	d.	d.	PROPN
admet-3065	859	5	niculescu	niculescu	PROPN
admet-3065	859	6	-	-	PUNCT
admet-3065	859	7	duvaz	duvaz	PROPN
admet-3065	859	8	,	,	PUNCT
admet-3065	859	9	j.	j.	PROPN
admet-3065	859	10	heyes	heyes	PROPN
admet-3065	859	11	,	,	PUNCT
admet-3065	859	12	c.	c.	PROPN
admet-3065	859	13	springer	springer	NOUN
admet-3065	859	14	.	.	PUNCT
admet-3065	860	1	structure	structure	NOUN
admet-3065	860	2	-	-	PUNCT
admet-3065	860	3	activity	activity	NOUN
admet-3065	860	4	relationship	relationship	NOUN
admet-3065	860	5	in	in	ADP
admet-3065	860	6	cationic	cationic	ADJ
admet-3065	860	7	lipid	lipid	NOUN
admet-3065	860	8	mediated	mediate	VERB
admet-3065	860	9	gene	gene	NOUN
admet-3065	860	10	transfection	transfection	NOUN
admet-3065	860	11	.	.	PUNCT
admet-3065	861	1	current	current	ADJ
admet-3065	861	2	medicinal	medicinal	ADJ
admet-3065	861	3	chemistry	chemistry	NOUN
admet-3065	861	4	10	10	NUM
admet-3065	861	5	(	(	PUNCT
admet-3065	861	6	2003	2003	NUM
admet-3065	861	7	)	)	PUNCT
admet-3065	861	8	1233	1233	NUM
admet-3065	861	9	-	-	SYM
admet-3065	861	10	1261	1261	NUM
admet-3065	861	11	.	.	PUNCT
admet-3065	861	12	https://doi.org/10.2174/0929867033457476	https://doi.org/10.2174/0929867033457476	X
admet-3065	862	1	[	[	X
admet-3065	862	2	121	121	NUM
admet-3065	862	3	]	]	PUNCT
admet-3065	862	4	r.	r.	PROPN
admet-3065	862	5	koynova	koynova	PROPN
admet-3065	862	6	,	,	PUNCT
admet-3065	862	7	b.	b.	PROPN
admet-3065	862	8	tenchov	tenchov	PROPN
admet-3065	862	9	.	.	PUNCT
admet-3065	863	1	cationic	cationic	ADJ
admet-3065	863	2	phospholipids	phospholipid	NOUN
admet-3065	863	3	:	:	PUNCT
admet-3065	863	4	structure	structure	NOUN
admet-3065	863	5	-	-	PUNCT
admet-3065	863	6	transfection	transfection	NOUN
admet-3065	863	7	activity	activity	NOUN
admet-3065	863	8	relationships	relationship	NOUN
admet-3065	863	9	.	.	PUNCT
admet-3065	864	1	soft	soft	ADJ
admet-3065	864	2	matter	matter	NOUN
admet-3065	864	3	5	5	NUM
admet-3065	864	4	(	(	PUNCT
admet-3065	864	5	2009	2009	NUM
admet-3065	864	6	)	)	PUNCT
admet-3065	864	7	3187	3187	NUM
admet-3065	864	8	-	-	SYM
admet-3065	864	9	3200	3200	NUM
admet-3065	864	10	.	.	PUNCT
admet-3065	865	1	https://doi.org/10.1039/b902027f	https://doi.org/10.1039/b902027f	PROPN
admet-3065	865	2	[	[	X
admet-3065	865	3	122	122	NUM
admet-3065	865	4	]	]	X
admet-3065	865	5	c.l	c.l	PROPN
admet-3065	865	6	.	.	PROPN
admet-3065	865	7	walsh	walsh	PROPN
admet-3065	865	8	,	,	PUNCT
admet-3065	865	9	j.	j.	PROPN
admet-3065	865	10	nguyen	nguyen	PROPN
admet-3065	865	11	,	,	PUNCT
admet-3065	865	12	m.r	m.r	PROPN
admet-3065	865	13	.	.	PROPN
admet-3065	865	14	tiffany	tiffany	PROPN
admet-3065	865	15	,	,	PUNCT
admet-3065	865	16	f.c	f.c	PROPN
admet-3065	865	17	.	.	PROPN
admet-3065	865	18	szoka	szoka	PROPN
admet-3065	865	19	.	.	PUNCT
admet-3065	866	1	synthesis	synthesis	NOUN
admet-3065	866	2	,	,	PUNCT
admet-3065	866	3	characterization	characterization	NOUN
admet-3065	866	4	and	and	CCONJ
admet-3065	866	5	evaluation	evaluation	NOUN
admet-3065	866	6	of	of	ADP
admet-3065	866	7	ionizable	ionizable	ADJ
admet-3065	866	8	lysine	lysine	NOUN
admet-3065	866	9	-	-	PUNCT
admet-3065	866	10	based	base	VERB
admet-3065	866	11	lipids	lipid	NOUN
admet-3065	866	12	for	for	ADP
admet-3065	866	13	sirna	sirna	PROPN
admet-3065	866	14	delivery	delivery	NOUN
admet-3065	866	15	.	.	PUNCT
admet-3065	867	1	bioconjugate	bioconjugate	NOUN
admet-3065	867	2	chemistry	chemistry	NOUN
admet-3065	867	3	24	24	NUM
admet-3065	867	4	(	(	PUNCT
admet-3065	867	5	2012	2012	NUM
admet-3065	867	6	)	)	PUNCT
admet-3065	867	7	36	36	NUM
admet-3065	867	8	.	.	PUNCT
admet-3065	868	1	https://doi.org/10.1021/bc300346h	https://doi.org/10.1021/bc300346h	NOUN
admet-3065	868	2	.	.	PUNCT
admet-3065	869	1	[	[	X
admet-3065	869	2	123	123	NUM
admet-3065	869	3	]	]	PUNCT
admet-3065	869	4	c.	c.	PROPN
admet-3065	869	5	pennetta	pennetta	PROPN
admet-3065	869	6	,	,	PUNCT
admet-3065	869	7	n.	n.	PROPN
admet-3065	869	8	bono	bono	X
admet-3065	869	9	,	,	PUNCT
admet-3065	869	10	f.	f.	PROPN
admet-3065	869	11	ponti	ponti	PROPN
admet-3065	869	12	,	,	PUNCT
admet-3065	869	13	m.c	m.c	PROPN
admet-3065	869	14	.	.	PROPN
admet-3065	869	15	bellucci	bellucci	PROPN
admet-3065	869	16	,	,	PUNCT
admet-3065	869	17	f.	f.	PROPN
admet-3065	869	18	viani	viani	PROPN
admet-3065	869	19	,	,	PUNCT
admet-3065	869	20	g.	g.	PROPN
admet-3065	869	21	candiani	candiani	PROPN
admet-3065	869	22	,	,	PUNCT
admet-3065	869	23	a.	a.	PROPN
admet-3065	869	24	volonterio	volonterio	PROPN
admet-3065	869	25	.	.	PUNCT
admet-3065	870	1	multifunctional	multifunctional	ADJ
admet-3065	870	2	neomycin	neomycin	PROPN
admet-3065	870	3	-	-	PUNCT
admet-3065	870	4	triazine	triazine	NOUN
admet-3065	870	5	-	-	PUNCT
admet-3065	870	6	based	base	VERB
admet-3065	870	7	cationic	cationic	NOUN
admet-3065	870	8	lipids	lipid	NOUN
admet-3065	870	9	for	for	ADP
admet-3065	870	10	gene	gene	NOUN
admet-3065	870	11	delivery	delivery	NOUN
admet-3065	870	12	with	with	ADP
admet-3065	870	13	antibacterial	antibacterial	ADJ
admet-3065	870	14	properties	property	NOUN
admet-3065	870	15	.	.	PUNCT
admet-3065	871	1	bioconjugate	bioconjugate	NOUN
admet-3065	871	2	chemistry	chemistry	NOUN
admet-3065	871	3	32	32	NUM
admet-3065	871	4	(	(	PUNCT
admet-3065	871	5	2021	2021	NUM
admet-3065	871	6	)	)	PUNCT
admet-3065	871	7	690	690	NUM
admet-3065	871	8	-	-	SYM
admet-3065	871	9	701	701	NUM
admet-3065	871	10	.	.	PUNCT
admet-3065	872	1	https://doi.org/10.1021/acs.bioconjchem.0c00616	https://doi.org/10.1021/acs.bioconjchem.0c00616	X
admet-3065	873	1	[	[	X
admet-3065	873	2	124	124	NUM
admet-3065	873	3	]	]	X
admet-3065	873	4	k.w.c	k.w.c	NOUN
admet-3065	873	5	.	.	PUNCT
admet-3065	873	6	mok	mok	PROPN
admet-3065	873	7	,	,	PUNCT
admet-3065	873	8	p.r	p.r	PROPN
admet-3065	873	9	.	.	PROPN
admet-3065	873	10	cullis	cullis	PROPN
admet-3065	873	11	.	.	PUNCT
admet-3065	874	1	structural	structural	ADJ
admet-3065	874	2	and	and	CCONJ
admet-3065	874	3	fusogenic	fusogenic	ADJ
admet-3065	874	4	properties	property	NOUN
admet-3065	874	5	of	of	ADP
admet-3065	874	6	cationic	cationic	ADJ
admet-3065	874	7	liposomes	liposome	NOUN
admet-3065	874	8	in	in	ADP
admet-3065	874	9	the	the	DET
admet-3065	874	10	presence	presence	NOUN
admet-3065	874	11	of	of	ADP
admet-3065	874	12	plasmid	plasmid	ADJ
admet-3065	874	13	dna	dna	NOUN
admet-3065	874	14	.	.	PUNCT
admet-3065	875	1	biophysical	biophysical	ADJ
admet-3065	875	2	journal	journal	NOUN
admet-3065	875	3	73	73	NUM
admet-3065	875	4	(	(	PUNCT
admet-3065	875	5	1997	1997	NUM
admet-3065	875	6	)	)	PUNCT
admet-3065	875	7	2534	2534	NUM
admet-3065	875	8	-	-	SYM
admet-3065	875	9	2545	2545	NUM
admet-3065	875	10	.	.	PUNCT
admet-3065	876	1	https://doi.org/10.1016/s00063495(97)78282-1	https://doi.org/10.1016/s00063495(97)78282-1	X
admet-3065	877	1	[	[	X
admet-3065	877	2	125	125	NUM
admet-3065	877	3	]	]	PUNCT
admet-3065	877	4	f.	f.	PROPN
admet-3065	877	5	tang	tang	PROPN
admet-3065	877	6	,	,	PUNCT
admet-3065	877	7	j.a	j.a	PROPN
admet-3065	877	8	.	.	PROPN
admet-3065	877	9	hughes	hughe	NOUN
admet-3065	877	10	.	.	PUNCT
admet-3065	878	1	synthesis	synthesis	NOUN
admet-3065	878	2	of	of	ADP
admet-3065	878	3	a	a	DET
admet-3065	878	4	single	single	ADJ
admet-3065	878	5	-	-	PUNCT
admet-3065	878	6	tailed	tail	VERB
admet-3065	878	7	cationic	cationic	ADJ
admet-3065	878	8	lipid	lipid	NOUN
admet-3065	878	9	and	and	CCONJ
admet-3065	878	10	investigation	investigation	NOUN
admet-3065	878	11	of	of	ADP
admet-3065	878	12	its	its	PRON
admet-3065	878	13	transfection	transfection	NOUN
admet-3065	878	14	.	.	PUNCT
admet-3065	879	1	journal	journal	PROPN
admet-3065	879	2	of	of	ADP
admet-3065	879	3	controlled	control	VERB
admet-3065	879	4	release	release	NOUN
admet-3065	879	5	62	62	NUM
admet-3065	879	6	(	(	PUNCT
admet-3065	879	7	1999	1999	NUM
admet-3065	879	8	)	)	PUNCT
admet-3065	879	9	345	345	NUM
admet-3065	879	10	-	-	SYM
admet-3065	879	11	358	358	NUM
admet-3065	879	12	.	.	PUNCT
admet-3065	880	1	https://doi.org/10.1016/s0168-3659(99)00158-3	https://doi.org/10.1016/s0168-3659(99)00158-3	VERB
admet-3065	881	1	[	[	X
admet-3065	881	2	126	126	NUM
admet-3065	881	3	]	]	PUNCT
admet-3065	881	4	l.	l.	PROPN
admet-3065	881	5	wang	wang	PROPN
admet-3065	881	6	,	,	PUNCT
admet-3065	881	7	r.c	r.c	PROPN
admet-3065	881	8	.	.	PROPN
admet-3065	881	9	macdonald	macdonald	PROPN
admet-3065	881	10	.	.	PUNCT
admet-3065	882	1	new	new	ADJ
admet-3065	882	2	strategy	strategy	NOUN
admet-3065	882	3	for	for	ADP
admet-3065	882	4	transfection	transfection	NOUN
admet-3065	882	5	:	:	PUNCT
admet-3065	882	6	mixtures	mixture	NOUN
admet-3065	882	7	of	of	ADP
admet-3065	882	8	medium	medium	NOUN
admet-3065	882	9	-	-	PUNCT
admet-3065	882	10	chain	chain	NOUN
admet-3065	882	11	and	and	CCONJ
admet-3065	882	12	long	long	ADJ
admet-3065	882	13	-	-	PUNCT
admet-3065	882	14	chain	chain	NOUN
admet-3065	882	15	cationic	cationic	NOUN
admet-3065	882	16	lipids	lipid	NOUN
admet-3065	882	17	synergistically	synergistically	ADV
admet-3065	882	18	enhance	enhance	VERB
admet-3065	882	19	transfection	transfection	NOUN
admet-3065	882	20	.	.	PUNCT
admet-3065	883	1	gene	gene	NOUN
admet-3065	883	2	therapy	therapy	NOUN
admet-3065	883	3	11	11	NUM
admet-3065	883	4	(	(	PUNCT
admet-3065	883	5	2004	2004	NUM
admet-3065	883	6	)	)	PUNCT
admet-3065	883	7	1358	1358	NUM
admet-3065	883	8	-	-	SYM
admet-3065	883	9	1362	1362	NUM
admet-3065	883	10	.	.	PUNCT
admet-3065	884	1	https://doi.org/10.1038/sj.gt.3302297	https://doi.org/10.1038/sj.gt.3302297	PROPN
admet-3065	885	1	[	[	X
admet-3065	885	2	127	127	NUM
admet-3065	885	3	]	]	X
admet-3065	885	4	s.	s.	PROPN
admet-3065	885	5	arpicco	arpicco	PROPN
admet-3065	885	6	,	,	PUNCT
admet-3065	885	7	s.	s.	PROPN
admet-3065	885	8	canevari	canevari	PROPN
admet-3065	885	9	,	,	PUNCT
admet-3065	885	10	m.	m.	NOUN
admet-3065	885	11	ceruti	ceruti	PROPN
admet-3065	885	12	,	,	PUNCT
admet-3065	885	13	e.	e.	PROPN
admet-3065	885	14	galmozzi	galmozzi	PROPN
admet-3065	885	15	,	,	PUNCT
admet-3065	885	16	f.	f.	PROPN
admet-3065	885	17	rocco	rocco	PROPN
admet-3065	885	18	,	,	PUNCT
admet-3065	885	19	l.	l.	PROPN
admet-3065	885	20	cattel	cattel	PROPN
admet-3065	885	21	.	.	PUNCT
admet-3065	886	1	synthesis	synthesis	NOUN
admet-3065	886	2	,	,	PUNCT
admet-3065	886	3	characterization	characterization	NOUN
admet-3065	886	4	and	and	CCONJ
admet-3065	886	5	transfection	transfection	NOUN
admet-3065	886	6	activity	activity	NOUN
admet-3065	886	7	of	of	ADP
admet-3065	886	8	new	new	ADJ
admet-3065	886	9	saturated	saturated	ADJ
admet-3065	886	10	and	and	CCONJ
admet-3065	886	11	unsaturated	unsaturated	ADJ
admet-3065	886	12	cationic	cationic	ADJ
admet-3065	886	13	lipids	lipid	NOUN
admet-3065	886	14	.	.	PUNCT
admet-3065	887	1	farmaco	farmaco	PROPN
admet-3065	887	2	59	59	NUM
admet-3065	887	3	(	(	PUNCT
admet-3065	887	4	2004	2004	NUM
admet-3065	887	5	)	)	PUNCT
admet-3065	887	6	869	869	NUM
admet-3065	887	7	-	-	SYM
admet-3065	887	8	878	878	NUM
admet-3065	887	9	.	.	PUNCT
admet-3065	888	1	https://doi.org/10.1016/j.farmac.2004.06.007	https://doi.org/10.1016/j.farmac.2004.06.007	VERB
admet-3065	888	2	.	.	PUNCT
admet-3065	889	1	https://doi.org/10.1002/ana.10688	https://doi.org/10.1002/ana.10688	PROPN
admet-3065	889	2	https://doi.org/10.1016/s0006-3495(97)78214-6	https://doi.org/10.1016/s0006-3495(97)78214-6	PROPN
admet-3065	889	3	https://doi.org/10.3109/10717544.2014.882469	https://doi.org/10.3109/10717544.2014.882469	PUNCT
admet-3065	890	1	https://doi.org/10.1016/s0014-5793(97)00505-x	https://doi.org/10.1016/s0014-5793(97)00505-x	ADJ
admet-3065	890	2	https://doi.org/10.1016/j.cbpa.2024.102552	https://doi.org/10.1016/j.cbpa.2024.102552	ADJ
admet-3065	890	3	https://doi.org/10.1021/acs.bioconjchem.7b00471	https://doi.org/10.1021/acs.bioconjchem.7b00471	PROPN
admet-3065	890	4	https://doi.org/10.4172/2161-0444.1000225	https://doi.org/10.4172/2161-0444.1000225	PROPN
admet-3065	890	5	https://doi.org/10.1021/acs.biochem.0c00860	https://doi.org/10.1021/acs.biochem.0c00860	VERB
admet-3065	890	6	https://doi.org/10.1038/sj.gt.3302843	https://doi.org/10.1038/sj.gt.3302843	PROPN
admet-3065	890	7	https://doi.org/14513676	https://doi.org/14513676	PROPN
admet-3065	890	8	  	  	SPACE
admet-3065	890	9	https://doi.org/10.2174/0929867033457476	https://doi.org/10.2174/0929867033457476	NOUN
admet-3065	890	10	https://doi.org/10.1039/b902027f	https://doi.org/10.1039/b902027f	NOUN
admet-3065	890	11	https://doi.org/10.1021/bc300346h	https://doi.org/10.1021/bc300346h	NOUN
admet-3065	890	12	https://doi.org/10.1021/acs.bioconjchem.0c00616	https://doi.org/10.1021/acs.bioconjchem.0c00616	PRON
admet-3065	890	13	https://doi.org/10.1016/s0006-3495(97)78282-1	https://doi.org/10.1016/s0006-3495(97)78282-1	PROPN
admet-3065	890	14	https://doi.org/10.1016/s0006-3495(97)78282-1	https://doi.org/10.1016/s0006-3495(97)78282-1	PROPN
admet-3065	890	15	https://doi.org/10.1016/s0168-3659(99)00158-3	https://doi.org/10.1016/s0168-3659(99)00158-3	PROPN
admet-3065	890	16	https://doi.org/10.1038/sj.gt.3302297	https://doi.org/10.1038/sj.gt.3302297	PROPN
admet-3065	890	17	https://doi.org/10.1016/j.farmac.2004.06.007	https://doi.org/10.1016/j.farmac.2004.06.007	PROPN
admet-3065	890	18	.	.	PUNCT
admet-3065	891	1	e.	e.	PROPN
admet-3065	891	2	j.	j.	PROPN
admet-3065	891	3	saleh	saleh	PROPN
admet-3065	891	4	et	et	PROPN
admet-3065	891	5	al	al	PROPN
admet-3065	891	6	.	.	PROPN
admet-3065	891	7	admet	admet	PROPN
admet-3065	891	8	&	&	CCONJ
admet-3065	891	9	dmpk	dmpk	PROPN
admet-3065	891	10	00(0	00(0	PROPN
admet-3065	891	11	)	)	PUNCT
admet-3065	891	12	(	(	PUNCT
admet-3065	891	13	2025	2025	NUM
admet-3065	891	14	)	)	PUNCT
admet-3065	891	15	3065	3065	NUM
admet-3065	891	16	26	26	NUM
admet-3065	892	1	[	[	X
admet-3065	892	2	128	128	NUM
admet-3065	892	3	]	]	PUNCT
admet-3065	892	4	k.	k.	PROPN
admet-3065	892	5	ewert	ewert	PROPN
admet-3065	892	6	,	,	PUNCT
admet-3065	892	7	a.	a.	PROPN
admet-3065	892	8	ahmad	ahmad	PROPN
admet-3065	892	9	,	,	PUNCT
admet-3065	892	10	h.m	h.m	PROPN
admet-3065	892	11	.	.	PROPN
admet-3065	892	12	evans	evans	PROPN
admet-3065	892	13	,	,	PUNCT
admet-3065	892	14	h.w	h.w	PROPN
admet-3065	892	15	.	.	PROPN
admet-3065	892	16	schmidt	schmidt	PROPN
admet-3065	892	17	,	,	PUNCT
admet-3065	892	18	c.r	c.r	PROPN
admet-3065	892	19	.	.	PROPN
admet-3065	893	1	safinya	safinya	PROPN
admet-3065	893	2	.	.	PUNCT
admet-3065	894	1	efficient	efficient	ADJ
admet-3065	894	2	synthesis	synthesis	NOUN
admet-3065	894	3	and	and	CCONJ
admet-3065	894	4	cell	cell	NOUN
admet-3065	894	5	-	-	PUNCT
admet-3065	894	6	transfection	transfection	NOUN
admet-3065	894	7	properties	property	NOUN
admet-3065	894	8	of	of	ADP
admet-3065	894	9	a	a	DET
admet-3065	894	10	new	new	ADJ
admet-3065	894	11	multivalent	multivalent	NOUN
admet-3065	894	12	cationic	cationic	ADJ
admet-3065	894	13	lipid	lipid	NOUN
admet-3065	894	14	for	for	ADP
admet-3065	894	15	nonviral	nonviral	ADJ
admet-3065	894	16	gene	gene	NOUN
admet-3065	894	17	delivery	delivery	NOUN
admet-3065	894	18	.	.	PUNCT
admet-3065	895	1	journal	journal	NOUN
admet-3065	895	2	of	of	ADP
admet-3065	895	3	medicinal	medicinal	ADJ
admet-3065	895	4	chemistry	chemistry	NOUN
admet-3065	895	5	45	45	NUM
admet-3065	895	6	(	(	PUNCT
admet-3065	895	7	2002	2002	NUM
admet-3065	895	8	)	)	PUNCT
admet-3065	895	9	5023	5023	NUM
admet-3065	895	10	-	-	SYM
admet-3065	895	11	5029	5029	NUM
admet-3065	895	12	.	.	PUNCT
admet-3065	895	13	https://doi.org/10.1021/jm020233w	https://doi.org/10.1021/jm020233w	PROPN
admet-3065	896	1	[	[	X
admet-3065	896	2	129	129	NUM
admet-3065	896	3	]	]	PUNCT
admet-3065	896	4	e.	e.	PROPN
admet-3065	896	5	yuba	yuba	PROPN
admet-3065	896	6	,	,	PUNCT
admet-3065	896	7	y.	y.	PROPN
admet-3065	896	8	nakajima	nakajima	PROPN
admet-3065	896	9	,	,	PUNCT
admet-3065	896	10	k.	k.	PROPN
admet-3065	896	11	tsukamoto	tsukamoto	PROPN
admet-3065	896	12	,	,	PUNCT
admet-3065	896	13	s.	s.	PROPN
admet-3065	896	14	iwashita	iwashita	PROPN
admet-3065	896	15	,	,	PUNCT
admet-3065	896	16	c.	c.	PROPN
admet-3065	896	17	kojima	kojima	PROPN
admet-3065	896	18	,	,	PUNCT
admet-3065	896	19	a.	a.	PROPN
admet-3065	896	20	harada	harada	PROPN
admet-3065	896	21	,	,	PUNCT
admet-3065	896	22	k.	k.	PROPN
admet-3065	896	23	kono	kono	PROPN
admet-3065	896	24	.	.	PUNCT
admet-3065	897	1	effect	effect	NOUN
admet-3065	897	2	of	of	ADP
admet-3065	897	3	unsaturated	unsaturated	ADJ
admet-3065	897	4	alkyl	alkyl	NOUN
admet-3065	897	5	chains	chain	NOUN
admet-3065	897	6	on	on	ADP
admet-3065	897	7	transfection	transfection	NOUN
admet-3065	897	8	activity	activity	NOUN
admet-3065	897	9	of	of	ADP
admet-3065	897	10	poly(amidoamine	poly(amidoamine	PROPN
admet-3065	897	11	)	)	PUNCT
admet-3065	897	12	dendron	dendron	NOUN
admet-3065	897	13	-	-	PUNCT
admet-3065	897	14	bearing	bear	VERB
admet-3065	897	15	lipids	lipid	NOUN
admet-3065	897	16	.	.	PUNCT
admet-3065	898	1	journal	journal	PROPN
admet-3065	898	2	of	of	ADP
admet-3065	898	3	controlled	control	VERB
admet-3065	898	4	release	release	NOUN
admet-3065	898	5	160	160	NUM
admet-3065	898	6	(	(	PUNCT
admet-3065	898	7	2012	2012	NUM
admet-3065	898	8	)	)	PUNCT
admet-3065	898	9	552	552	NUM
admet-3065	898	10	-	-	SYM
admet-3065	898	11	560	560	NUM
admet-3065	898	12	.	.	PUNCT
admet-3065	899	1	https://doi.org/10.1016/j.jconrel.2012.04.002	https://doi.org/10.1016/j.jconrel.2012.04.002	NOUN
admet-3065	899	2	[	[	X
admet-3065	899	3	130	130	NUM
admet-3065	899	4	]	]	PUNCT
admet-3065	899	5	g.	g.	PROPN
admet-3065	899	6	gaynanova	gaynanova	PROPN
admet-3065	899	7	,	,	PUNCT
admet-3065	899	8	l.	l.	PROPN
admet-3065	899	9	vasileva	vasileva	PROPN
admet-3065	899	10	,	,	PUNCT
admet-3065	899	11	r.	r.	PROPN
admet-3065	899	12	kashapov	kashapov	PROPN
admet-3065	899	13	,	,	PUNCT
admet-3065	899	14	d.	d.	PROPN
admet-3065	899	15	kuznetsova	kuznetsova	PROPN
admet-3065	899	16	,	,	PUNCT
admet-3065	899	17	r.	r.	PROPN
admet-3065	899	18	kushnazarova	kushnazarova	PROPN
admet-3065	899	19	,	,	PUNCT
admet-3065	899	20	a.	a.	PROPN
admet-3065	899	21	tyryshkina	tyryshkina	PROPN
admet-3065	899	22	,	,	PUNCT
admet-3065	899	23	e.	e.	PROPN
admet-3065	899	24	vasilieva	vasilieva	PROPN
admet-3065	899	25	,	,	PUNCT
admet-3065	899	26	k.	k.	PROPN
admet-3065	899	27	petrov	petrov	PROPN
admet-3065	899	28	,	,	PUNCT
admet-3065	899	29	l.	l.	PROPN
admet-3065	899	30	zakharova	zakharova	PROPN
admet-3065	899	31	,	,	PUNCT
admet-3065	899	32	o.	o.	PROPN
admet-3065	899	33	sinyashin	sinyashin	PROPN
admet-3065	899	34	.	.	PUNCT
admet-3065	899	35	self	self	NOUN
admet-3065	899	36	-	-	PUNCT
admet-3065	899	37	assembling	assemble	VERB
admet-3065	899	38	drug	drug	NOUN
admet-3065	899	39	formulations	formulation	NOUN
admet-3065	899	40	with	with	ADP
admet-3065	899	41	tunable	tunable	ADJ
admet-3065	899	42	permeability	permeability	NOUN
admet-3065	899	43	and	and	CCONJ
admet-3065	899	44	biodegradability	biodegradability	NOUN
admet-3065	899	45	.	.	PUNCT
admet-3065	900	1	molecules	molecule	NOUN
admet-3065	900	2	26	26	NUM
admet-3065	900	3	(	(	PUNCT
admet-3065	900	4	2021	2021	NUM
admet-3065	900	5	)	)	PUNCT
admet-3065	900	6	6786	6786	NUM
admet-3065	900	7	.	.	PUNCT
admet-3065	901	1	https://doi.org/10.3390/molecules26226786	https://doi.org/10.3390/molecules26226786	PROPN
admet-3065	902	1	[	[	X
admet-3065	902	2	131	131	NUM
admet-3065	902	3	]	]	X
admet-3065	902	4	a.	a.	NOUN
admet-3065	902	5	bajaj	bajaj	PROPN
admet-3065	902	6	,	,	PUNCT
admet-3065	902	7	p.	p.	PROPN
admet-3065	902	8	kondiah	kondiah	PROPN
admet-3065	902	9	,	,	PUNCT
admet-3065	902	10	s.	s.	PROPN
admet-3065	902	11	bhattacharya	bhattacharya	PROPN
admet-3065	902	12	.	.	PUNCT
admet-3065	903	1	effect	effect	NOUN
admet-3065	903	2	of	of	ADP
admet-3065	903	3	the	the	DET
admet-3065	903	4	nature	nature	NOUN
admet-3065	903	5	of	of	ADP
admet-3065	903	6	the	the	DET
admet-3065	903	7	counteranion	counteranion	NOUN
admet-3065	903	8	on	on	ADP
admet-3065	903	9	the	the	DET
admet-3065	903	10	properties	property	NOUN
admet-3065	903	11	of	of	ADP
admet-3065	903	12	anionic	anionic	ADJ
admet-3065	903	13	surfactants	surfactant	NOUN
admet-3065	903	14	.	.	PUNCT
admet-3065	904	1	1	1	X
admet-3065	904	2	.	.	X
admet-3065	904	3	cmc	cmc	NOUN
admet-3065	904	4	,	,	PUNCT
admet-3065	904	5	ionization	ionization	NOUN
admet-3065	904	6	degree	degree	NOUN
admet-3065	904	7	at	at	ADP
admet-3065	904	8	the	the	DET
admet-3065	904	9	cmc	cmc	NOUN
admet-3065	904	10	and	and	CCONJ
admet-3065	904	11	aggregation	aggregation	NOUN
admet-3065	904	12	number	number	NOUN
admet-3065	904	13	of	of	ADP
admet-3065	904	14	micelles	micelle	NOUN
admet-3065	904	15	of	of	ADP
admet-3065	904	16	decylammonium	decylammonium	NOUN
admet-3065	904	17	,	,	PUNCT
admet-3065	904	18	dodecylammonium	dodecylammonium	NOUN
admet-3065	904	19	,	,	PUNCT
admet-3065	904	20	decyltrimethylammonium	decyltrimethylammonium	NOUN
admet-3065	904	21	,	,	PUNCT
admet-3065	904	22	and	and	CCONJ
admet-3065	904	23	dodecyltrimethylammonium	dodecyltrimethylammonium	NOUN
admet-3065	904	24	halides	halide	NOUN
admet-3065	904	25	.	.	PUNCT
admet-3065	905	1	the	the	DET
admet-3065	905	2	journal	journal	NOUN
admet-3065	905	3	of	of	ADP
admet-3065	905	4	physical	physical	ADJ
admet-3065	905	5	chemistry	chemistry	NOUN
admet-3065	905	6	b	b	PROPN
admet-3065	905	7	111	111	NUM
admet-3065	905	8	(	(	PUNCT
admet-3065	905	9	2007	2007	NUM
admet-3065	905	10	)	)	PUNCT
admet-3065	905	11	1238	1238	NUM
admet-3065	905	12	-	-	SYM
admet-3065	905	13	1243	1243	NUM
admet-3065	905	14	.	.	PUNCT
admet-3065	906	1	https://doi.org/10.1021/j100270a040	https://doi.org/10.1021/j100270a040	NOUN
admet-3065	907	1	[	[	X
admet-3065	907	2	132	132	NUM
admet-3065	907	3	]	]	X
admet-3065	907	4	r.	r.	PROPN
admet-3065	907	5	sheng	sheng	PROPN
admet-3065	907	6	,	,	PUNCT
admet-3065	907	7	x.	x.	PROPN
admet-3065	907	8	zhuang	zhuang	PROPN
admet-3065	907	9	,	,	PUNCT
admet-3065	907	10	z.	z.	PROPN
admet-3065	907	11	wang	wang	PROPN
admet-3065	907	12	,	,	PUNCT
admet-3065	907	13	a.	a.	PROPN
admet-3065	907	14	cao	cao	PROPN
admet-3065	907	15	,	,	PUNCT
admet-3065	907	16	k.	k.	PROPN
admet-3065	907	17	lin	lin	PROPN
admet-3065	907	18	,	,	PUNCT
admet-3065	907	19	j.x.x	j.x.x	NOUN
admet-3065	907	20	.	.	PUNCT
admet-3065	908	1	zhu	zhu	PROPN
admet-3065	908	2	.	.	PUNCT
admet-3065	909	1	cationic	cationic	ADJ
admet-3065	909	2	nanoparticles	nanoparticle	NOUN
admet-3065	909	3	assembled	assemble	VERB
admet-3065	909	4	from	from	ADP
admet-3065	909	5	natural	natural	ADJ
admet-3065	909	6	-	-	PUNCT
admet-3065	909	7	based	base	VERB
admet-3065	909	8	steroid	steroid	NOUN
admet-3065	909	9	lipid	lipid	NOUN
admet-3065	909	10	for	for	ADP
admet-3065	909	11	improved	improved	ADJ
admet-3065	909	12	intracellular	intracellular	ADJ
admet-3065	909	13	transport	transport	NOUN
admet-3065	909	14	of	of	ADP
admet-3065	909	15	sirna	sirna	PROPN
admet-3065	909	16	and	and	CCONJ
admet-3065	909	17	pdna	pdna	PROPN
admet-3065	909	18	.	.	PUNCT
admet-3065	910	1	nanomaterial	nanomaterial	PROPN
admet-3065	910	2	6	6	NUM
admet-3065	910	3	(	(	PUNCT
admet-3065	910	4	2016	2016	NUM
admet-3065	910	5	)	)	PUNCT
admet-3065	910	6	69	69	NUM
admet-3065	910	7	.	.	PUNCT
admet-3065	911	1	https://doi.org/10.3390/nano6040069	https://doi.org/10.3390/nano6040069	PROPN
admet-3065	911	2	[	[	X
admet-3065	911	3	133	133	NUM
admet-3065	911	4	]	]	PUNCT
admet-3065	911	5	n.	n.	NOUN
admet-3065	911	6	duhem	duhem	PROPN
admet-3065	911	7	,	,	PUNCT
admet-3065	911	8	f.	f.	PROPN
admet-3065	911	9	danhier	danhier	PROPN
admet-3065	911	10	,	,	PUNCT
admet-3065	911	11	v.	v.	ADP
admet-3065	911	12	préat	préat	NOUN
admet-3065	911	13	.	.	PUNCT
admet-3065	912	1	vitamin	vitamin	NOUN
admet-3065	912	2	e	e	NOUN
admet-3065	912	3	-	-	PUNCT
admet-3065	912	4	based	base	VERB
admet-3065	912	5	nanomedicines	nanomedicine	NOUN
admet-3065	912	6	for	for	ADP
admet-3065	912	7	anti	anti	ADJ
admet-3065	912	8	-	-	ADJ
admet-3065	912	9	cancer	cancer	ADJ
admet-3065	912	10	drug	drug	NOUN
admet-3065	912	11	delivery	delivery	NOUN
admet-3065	912	12	.	.	PUNCT
admet-3065	913	1	journal	journal	PROPN
admet-3065	913	2	of	of	ADP
admet-3065	913	3	controlled	control	VERB
admet-3065	913	4	release	release	NOUN
admet-3065	913	5	182	182	NUM
admet-3065	913	6	(	(	PUNCT
admet-3065	913	7	2014	2014	NUM
admet-3065	913	8	)	)	PUNCT
admet-3065	913	9	33	33	NUM
admet-3065	913	10	-	-	SYM
admet-3065	913	11	44	44	NUM
admet-3065	913	12	.	.	PUNCT
admet-3065	914	1	https://doi.org/10.1016/j.jconrel.2014.03.009	https://doi.org/10.1016/j.jconrel.2014.03.009	PROPN
admet-3065	915	1	[	[	X
admet-3065	915	2	134	134	NUM
admet-3065	915	3	]	]	PUNCT
admet-3065	915	4	l.	l.	PROPN
admet-3065	915	5	wasungu	wasungu	PROPN
admet-3065	915	6	,	,	PUNCT
admet-3065	915	7	d.	d.	PROPN
admet-3065	915	8	hoekstra	hoekstra	PROPN
admet-3065	915	9	.	.	PUNCT
admet-3065	915	10	cationic	cationic	ADJ
admet-3065	915	11	lipids	lipid	NOUN
admet-3065	915	12	,	,	PUNCT
admet-3065	915	13	lipoplexes	lipoplexe	NOUN
admet-3065	915	14	and	and	CCONJ
admet-3065	915	15	intracellular	intracellular	ADJ
admet-3065	915	16	delivery	delivery	NOUN
admet-3065	915	17	of	of	ADP
admet-3065	915	18	genes	gene	NOUN
admet-3065	915	19	.	.	PUNCT
admet-3065	916	1	journal	journal	PROPN
admet-3065	916	2	of	of	ADP
admet-3065	916	3	controlled	control	VERB
admet-3065	916	4	release	release	NOUN
admet-3065	916	5	116	116	NUM
admet-3065	916	6	(	(	PUNCT
admet-3065	916	7	2006	2006	NUM
admet-3065	916	8	)	)	PUNCT
admet-3065	916	9	255	255	NUM
admet-3065	916	10	-	-	SYM
admet-3065	916	11	264	264	NUM
admet-3065	916	12	.	.	PUNCT
admet-3065	917	1	https://doi.org/10.1016/j.jconrel.2006.06.024	https://doi.org/10.1016/j.jconrel.2006.06.024	NOUN
admet-3065	917	2	[	[	X
admet-3065	917	3	135	135	NUM
admet-3065	917	4	]	]	X
admet-3065	917	5	s.	s.	PROPN
admet-3065	917	6	sun	sun	PROPN
admet-3065	917	7	,	,	PUNCT
admet-3065	917	8	m.	m.	PROPN
admet-3065	917	9	wang	wang	PROPN
admet-3065	917	10	,	,	PUNCT
admet-3065	917	11	k.a	k.a	PROPN
admet-3065	917	12	.	.	PROPN
admet-3065	917	13	alberti	alberti	PROPN
admet-3065	917	14	,	,	PUNCT
admet-3065	917	15	a.	a.	NOUN
admet-3065	917	16	choy	choy	NOUN
admet-3065	917	17	,	,	PUNCT
admet-3065	917	18	q.	q.	PROPN
admet-3065	917	19	xu	xu	PROPN
admet-3065	917	20	.	.	PUNCT
admet-3065	918	1	dope	dope	NOUN
admet-3065	918	2	facilitates	facilitates	AUX
admet-3065	918	3	quaternized	quaternize	VERB
admet-3065	918	4	lipidoids	lipidoid	NOUN
admet-3065	918	5	(	(	PUNCT
admet-3065	918	6	qlds	qld	NOUN
admet-3065	918	7	)	)	PUNCT
admet-3065	918	8	for	for	ADP
admet-3065	918	9	in	in	ADP
admet-3065	918	10	vitro	vitro	X
admet-3065	918	11	dna	dna	PROPN
admet-3065	918	12	delivery	delivery	NOUN
admet-3065	918	13	.	.	PUNCT
admet-3065	919	1	nanomedicine	nanomedicine	NOUN
admet-3065	919	2	:	:	PUNCT
admet-3065	919	3	nanotechnology	nanotechnology	NOUN
admet-3065	919	4	,	,	PUNCT
admet-3065	919	5	biology	biology	NOUN
admet-3065	919	6	and	and	CCONJ
admet-3065	919	7	medicine	medicine	NOUN
admet-3065	919	8	9	9	NUM
admet-3065	919	9	(	(	PUNCT
admet-3065	919	10	2013	2013	NUM
admet-3065	919	11	)	)	PUNCT
admet-3065	919	12	849	849	NUM
admet-3065	919	13	-	-	SYM
admet-3065	919	14	854	854	NUM
admet-3065	919	15	.	.	PUNCT
admet-3065	920	1	https://doi.org/10.1016/j.nano.2013.01.006	https://doi.org/10.1016/j.nano.2013.01.006	ADJ
admet-3065	920	2	[	[	X
admet-3065	920	3	136	136	NUM
admet-3065	920	4	]	]	PUNCT
admet-3065	920	5	h.	h.	PROPN
admet-3065	920	6	chen	chen	PROPN
admet-3065	920	7	,	,	PUNCT
admet-3065	920	8	h.	h.	PROPN
admet-3065	920	9	zhang	zhang	PROPN
admet-3065	920	10	,	,	PUNCT
admet-3065	920	11	c.m	c.m	PROPN
admet-3065	920	12	.	.	PROPN
admet-3065	920	13	mccallum	mccallum	PROPN
admet-3065	920	14	,	,	PUNCT
admet-3065	920	15	f.c	f.c	PROPN
admet-3065	920	16	.	.	PROPN
admet-3065	920	17	szoka	szoka	PROPN
admet-3065	920	18	,	,	PUNCT
admet-3065	920	19	x.	x.	PROPN
admet-3065	920	20	guo	guo	PROPN
admet-3065	920	21	.	.	PUNCT
admet-3065	920	22	unsaturated	unsaturated	ADJ
admet-3065	920	23	cationic	cationic	ADJ
admet-3065	920	24	ortho	ortho	PROPN
admet-3065	920	25	esters	ester	NOUN
admet-3065	920	26	for	for	ADP
admet-3065	920	27	endosome	endosome	PROPN
admet-3065	920	28	permeation	permeation	NOUN
admet-3065	920	29	in	in	ADP
admet-3065	920	30	gene	gene	NOUN
admet-3065	920	31	delivery	delivery	NOUN
admet-3065	920	32	.	.	PUNCT
admet-3065	921	1	journal	journal	NOUN
admet-3065	921	2	of	of	ADP
admet-3065	921	3	medicinal	medicinal	ADJ
admet-3065	921	4	chemistry	chemistry	NOUN
admet-3065	921	5	50	50	NUM
admet-3065	921	6	(	(	PUNCT
admet-3065	921	7	2007	2007	NUM
admet-3065	921	8	)	)	PUNCT
admet-3065	921	9	4269	4269	NUM
admet-3065	921	10	-	-	SYM
admet-3065	921	11	4278	4278	NUM
admet-3065	921	12	.	.	PUNCT
admet-3065	922	1	https://doi.org/10.1021/jm060128c	https://doi.org/10.1021/jm060128c	PROPN
admet-3065	923	1	[	[	X
admet-3065	923	2	137	137	NUM
admet-3065	923	3	]	]	X
admet-3065	923	4	d.a	d.a	PROPN
admet-3065	923	5	.	.	PROPN
admet-3065	923	6	dean	dean	PROPN
admet-3065	923	7	,	,	PUNCT
admet-3065	923	8	j.z	j.z	PROPN
admet-3065	923	9	.	.	PROPN
admet-3065	923	10	gasiorowski	gasiorowski	PROPN
admet-3065	923	11	.	.	PUNCT
admet-3065	924	1	liposome	liposome	NOUN
admet-3065	924	2	-	-	PUNCT
admet-3065	924	3	mediated	mediate	VERB
admet-3065	924	4	transfection	transfection	NOUN
admet-3065	924	5	.	.	PUNCT
admet-3065	925	1	cold	cold	ADJ
admet-3065	925	2	spring	spring	NOUN
admet-3065	925	3	harbor	harbor	NOUN
admet-3065	925	4	protocols	protocol	NOUN
admet-3065	925	5	2011	2011	NUM
admet-3065	925	6	(	(	PUNCT
admet-3065	925	7	2011	2011	NUM
admet-3065	925	8	)	)	PUNCT
admet-3065	925	9	5583	5583	NUM
admet-3065	925	10	.	.	PUNCT
admet-3065	926	1	https://doi.org/10.1101/pdb.prot5583	https://doi.org/10.1101/pdb.prot5583	PROPN
admet-3065	927	1	[	[	X
admet-3065	927	2	138	138	NUM
admet-3065	927	3	]	]	X
admet-3065	927	4	[	[	X
admet-3065	927	5	136	136	NUM
admet-3065	927	6	]	]	PUNCT
admet-3065	927	7	z.	z.	PROPN
admet-3065	927	8	du	du	PROPN
admet-3065	927	9	,	,	PUNCT
admet-3065	927	10	m.m	m.m	PROPN
admet-3065	927	11	.	.	PROPN
admet-3065	927	12	munye	munye	PROPN
admet-3065	927	13	,	,	PUNCT
admet-3065	927	14	a.d	a.d	PROPN
admet-3065	927	15	.	.	PROPN
admet-3065	927	16	tagalakis	tagalakis	PROPN
admet-3065	927	17	,	,	PUNCT
admet-3065	927	18	m.d	m.d	PROPN
admet-3065	927	19	.	.	PROPN
admet-3065	927	20	manunta	manunta	PROPN
admet-3065	927	21	,	,	PUNCT
admet-3065	927	22	s.l	s.l	PROPN
admet-3065	927	23	.	.	PROPN
admet-3065	927	24	hart	hart	PROPN
admet-3065	927	25	.	.	PUNCT
admet-3065	928	1	the	the	DET
admet-3065	928	2	role	role	NOUN
admet-3065	928	3	of	of	ADP
admet-3065	928	4	the	the	DET
admet-3065	928	5	helper	helper	NOUN
admet-3065	928	6	lipid	lipid	NOUN
admet-3065	928	7	on	on	ADP
admet-3065	928	8	the	the	DET
admet-3065	928	9	dna	dna	PROPN
admet-3065	928	10	transfection	transfection	NOUN
admet-3065	928	11	efficiency	efficiency	NOUN
admet-3065	928	12	of	of	ADP
admet-3065	928	13	lipopolyplex	lipopolyplex	NOUN
admet-3065	928	14	formulations	formulation	NOUN
admet-3065	928	15	.	.	PUNCT
admet-3065	929	1	scientific	scientific	ADJ
admet-3065	929	2	reports	report	NOUN
admet-3065	929	3	4	4	NUM
admet-3065	929	4	(	(	PUNCT
admet-3065	929	5	2014	2014	NUM
admet-3065	929	6	)	)	PUNCT
admet-3065	929	7	7107	7107	NUM
admet-3065	929	8	-	-	SYM
admet-3065	929	9	7107	7107	NUM
admet-3065	929	10	.	.	PUNCT
admet-3065	930	1	https://doi.org/10.1038/srep07107	https://doi.org/10.1038/srep07107	VERB
admet-3065	930	2	[	[	X
admet-3065	930	3	139	139	NUM
admet-3065	930	4	]	]	PUNCT
admet-3065	930	5	r.	r.	PROPN
admet-3065	930	6	koynova	koynova	PROPN
admet-3065	930	7	,	,	PUNCT
admet-3065	930	8	l.	l.	PROPN
admet-3065	930	9	wang	wang	PROPN
admet-3065	930	10	,	,	PUNCT
admet-3065	930	11	r.c	r.c	PROPN
admet-3065	930	12	.	.	PROPN
admet-3065	930	13	macdonald	macdonald	PROPN
admet-3065	930	14	.	.	PUNCT
admet-3065	931	1	cationic	cationic	ADJ
admet-3065	931	2	phospholipids	phospholipid	NOUN
admet-3065	931	3	forming	form	VERB
admet-3065	931	4	cubic	cubic	ADJ
admet-3065	931	5	phases	phase	NOUN
admet-3065	931	6	:	:	PUNCT
admet-3065	931	7	lipoplex	lipoplex	NOUN
admet-3065	931	8	structure	structure	NOUN
admet-3065	931	9	and	and	CCONJ
admet-3065	931	10	transfection	transfection	NOUN
admet-3065	931	11	efficiency	efficiency	NOUN
admet-3065	931	12	.	.	PUNCT
admet-3065	932	1	molecular	molecular	ADJ
admet-3065	932	2	pharmaceutics	pharmaceutic	NOUN
admet-3065	932	3	5	5	NUM
admet-3065	932	4	(	(	PUNCT
admet-3065	932	5	2008	2008	NUM
admet-3065	932	6	)	)	PUNCT
admet-3065	932	7	739	739	NUM
admet-3065	932	8	-	-	SYM
admet-3065	932	9	744	744	NUM
admet-3065	932	10	.	.	PUNCT
admet-3065	933	1	https://doi.org/10.1021/mp800011e	https://doi.org/10.1021/mp800011e	PRON
admet-3065	934	1	[	[	X
admet-3065	934	2	140	140	NUM
admet-3065	934	3	]	]	X
admet-3065	934	4	a.	a.	NOUN
admet-3065	934	5	nagayasu	nagayasu	PROPN
admet-3065	934	6	,	,	PUNCT
admet-3065	934	7	k.	k.	PROPN
admet-3065	934	8	uchiyama	uchiyama	PROPN
admet-3065	934	9	,	,	PUNCT
admet-3065	934	10	h.	h.	PROPN
admet-3065	934	11	kiwada	kiwada	PROPN
admet-3065	934	12	.	.	PUNCT
admet-3065	935	1	the	the	DET
admet-3065	935	2	size	size	NOUN
admet-3065	935	3	of	of	ADP
admet-3065	935	4	liposomes	liposome	NOUN
admet-3065	935	5	:	:	PUNCT
admet-3065	935	6	a	a	DET
admet-3065	935	7	factor	factor	NOUN
admet-3065	935	8	which	which	PRON
admet-3065	935	9	affects	affect	VERB
admet-3065	935	10	their	their	PRON
admet-3065	935	11	targeting	targeting	NOUN
admet-3065	935	12	efficiency	efficiency	NOUN
admet-3065	935	13	to	to	ADP
admet-3065	935	14	tumors	tumor	NOUN
admet-3065	935	15	and	and	CCONJ
admet-3065	935	16	therapeutic	therapeutic	ADJ
admet-3065	935	17	activity	activity	NOUN
admet-3065	935	18	of	of	ADP
admet-3065	935	19	liposomal	liposomal	ADJ
admet-3065	935	20	antitumor	antitumor	PROPN
admet-3065	935	21	drugs	drug	NOUN
admet-3065	935	22	.	.	PUNCT
admet-3065	936	1	advanced	advanced	ADJ
admet-3065	936	2	drug	drug	NOUN
admet-3065	936	3	delivery	delivery	NOUN
admet-3065	936	4	reviews	review	VERB
admet-3065	936	5	40	40	NUM
admet-3065	936	6	(	(	PUNCT
admet-3065	936	7	1999	1999	NUM
admet-3065	936	8	)	)	PUNCT
admet-3065	936	9	75	75	NUM
admet-3065	936	10	-	-	SYM
admet-3065	936	11	87	87	NUM
admet-3065	936	12	.	.	PUNCT
admet-3065	937	1	https://doi.org/10.1016/s0169-409x(99)00041-1	https://doi.org/10.1016/s0169-409x(99)00041-1	PROPN
admet-3065	938	1	[	[	X
admet-3065	938	2	141	141	NUM
admet-3065	938	3	]	]	X
admet-3065	938	4	m.e	m.e	PROPN
admet-3065	938	5	.	.	PROPN
admet-3065	938	6	davis	davis	PROPN
admet-3065	938	7	,	,	PUNCT
admet-3065	938	8	z.	z.	PROPN
admet-3065	938	9	chen	chen	PROPN
admet-3065	938	10	,	,	PUNCT
admet-3065	938	11	d.m	d.m	PROPN
admet-3065	938	12	.	.	PROPN
admet-3065	938	13	shin	shin	PROPN
admet-3065	938	14	.	.	PUNCT
admet-3065	939	1	nanoparticle	nanoparticle	NOUN
admet-3065	939	2	therapeutics	therapeutic	NOUN
admet-3065	939	3	:	:	PUNCT
admet-3065	939	4	an	an	DET
admet-3065	939	5	emerging	emerge	VERB
admet-3065	939	6	treatment	treatment	NOUN
admet-3065	939	7	modality	modality	NOUN
admet-3065	939	8	for	for	ADP
admet-3065	939	9	cancer	cancer	NOUN
admet-3065	939	10	.	.	PUNCT
admet-3065	940	1	nature	nature	NOUN
admet-3065	940	2	reviews	review	VERB
admet-3065	940	3	drug	drug	NOUN
admet-3065	940	4	discovery	discovery	NOUN
admet-3065	940	5	7	7	NUM
admet-3065	940	6	(	(	PUNCT
admet-3065	940	7	2008	2008	NUM
admet-3065	940	8	)	)	PUNCT
admet-3065	940	9	771	771	NUM
admet-3065	940	10	-	-	SYM
admet-3065	940	11	782	782	NUM
admet-3065	940	12	.	.	PUNCT
admet-3065	941	1	https://doi.org/10.1038/nrd2614	https://doi.org/10.1038/nrd2614	X
admet-3065	941	2	.	.	PUNCT
admet-3065	942	1	[	[	X
admet-3065	942	2	142	142	NUM
admet-3065	942	3	]	]	X
admet-3065	942	4	m.e	m.e	PROPN
admet-3065	942	5	.	.	PROPN
admet-3065	942	6	davis	davis	PROPN
admet-3065	942	7	,	,	PUNCT
admet-3065	942	8	z.	z.	PROPN
admet-3065	942	9	chen	chen	PROPN
admet-3065	942	10	,	,	PUNCT
admet-3065	942	11	d.m	d.m	PROPN
admet-3065	942	12	.	.	PROPN
admet-3065	942	13	shin	shin	PROPN
admet-3065	942	14	.	.	PUNCT
admet-3065	943	1	nanoparticle	nanoparticle	NOUN
admet-3065	943	2	therapeutics	therapeutic	NOUN
admet-3065	943	3	:	:	PUNCT
admet-3065	943	4	an	an	DET
admet-3065	943	5	emerging	emerge	VERB
admet-3065	943	6	treatment	treatment	NOUN
admet-3065	943	7	modality	modality	NOUN
admet-3065	943	8	for	for	ADP
admet-3065	943	9	cancer	cancer	NOUN
admet-3065	943	10	.	.	PUNCT
admet-3065	944	1	nature	nature	NOUN
admet-3065	944	2	reviews	review	NOUN
admet-3065	944	3	.	.	PUNCT
admet-3065	945	1	drug	drug	NOUN
admet-3065	945	2	discovery	discovery	PROPN
admet-3065	945	3	7	7	NUM
admet-3065	945	4	(	(	PUNCT
admet-3065	945	5	2008	2008	NUM
admet-3065	945	6	)	)	PUNCT
admet-3065	945	7	771	771	NUM
admet-3065	945	8	-	-	SYM
admet-3065	945	9	782	782	NUM
admet-3065	945	10	.	.	PUNCT
admet-3065	946	1	https://doi.org/10.1038/nrd2614	https://doi.org/10.1038/nrd2614	PUNCT
admet-3065	947	1	[	[	X
admet-3065	947	2	143	143	X
admet-3065	947	3	]	]	X
admet-3065	947	4	f.	f.	PROPN
admet-3065	947	5	danhier	danhier	PROPN
admet-3065	947	6	.	.	PUNCT
admet-3065	948	1	to	to	PART
admet-3065	948	2	exploit	exploit	VERB
admet-3065	948	3	the	the	DET
admet-3065	948	4	tumor	tumor	NOUN
admet-3065	948	5	microenvironment	microenvironment	NOUN
admet-3065	948	6	:	:	PUNCT
admet-3065	948	7	since	since	SCONJ
admet-3065	948	8	the	the	DET
admet-3065	948	9	epr	epr	PROPN
admet-3065	948	10	effect	effect	NOUN
admet-3065	948	11	fails	fail	VERB
admet-3065	948	12	in	in	ADP
admet-3065	948	13	the	the	DET
admet-3065	948	14	clinic	clinic	NOUN
admet-3065	948	15	,	,	PUNCT
admet-3065	948	16	what	what	PRON
admet-3065	948	17	is	be	AUX
admet-3065	948	18	the	the	DET
admet-3065	948	19	future	future	NOUN
admet-3065	948	20	of	of	ADP
admet-3065	948	21	nanomedicine	nanomedicine	ADJ
admet-3065	948	22	?	?	PUNCT
admet-3065	949	1	journal	journal	PROPN
admet-3065	949	2	of	of	ADP
admet-3065	949	3	controlled	control	VERB
admet-3065	949	4	release	release	NOUN
admet-3065	949	5	244	244	NUM
admet-3065	949	6	(	(	PUNCT
admet-3065	949	7	2016	2016	NUM
admet-3065	949	8	)	)	PUNCT
admet-3065	949	9	108	108	NUM
admet-3065	949	10	-	-	SYM
admet-3065	949	11	121	121	NUM
admet-3065	949	12	.	.	PUNCT
admet-3065	950	1	https://doi.org/10.1016/j.jconrel.2016.11.015	https://doi.org/10.1016/j.jconrel.2016.11.015	PROPN
admet-3065	951	1	[	[	X
admet-3065	951	2	144	144	NUM
admet-3065	951	3	]	]	X
admet-3065	951	4	j.w	j.w	PROPN
admet-3065	951	5	.	.	PROPN
admet-3065	951	6	nichols	nichols	PROPN
admet-3065	951	7	,	,	PUNCT
admet-3065	951	8	y.h	y.h	PROPN
admet-3065	951	9	.	.	PROPN
admet-3065	951	10	bae	bae	PROPN
admet-3065	951	11	.	.	PUNCT
admet-3065	952	1	epr	epr	PROPN
admet-3065	952	2	:	:	PUNCT
admet-3065	952	3	evidence	evidence	NOUN
admet-3065	952	4	and	and	CCONJ
admet-3065	952	5	fallacy	fallacy	NOUN
admet-3065	952	6	.	.	PUNCT
admet-3065	953	1	journal	journal	NOUN
admet-3065	953	2	of	of	ADP
admet-3065	953	3	controlled	control	VERB
admet-3065	953	4	release	release	NOUN
admet-3065	953	5	190	190	NUM
admet-3065	953	6	(	(	PUNCT
admet-3065	953	7	2014	2014	NUM
admet-3065	953	8	)	)	PUNCT
admet-3065	953	9	451	451	NUM
admet-3065	953	10	-	-	SYM
admet-3065	953	11	464	464	NUM
admet-3065	953	12	.	.	PUNCT
admet-3065	954	1	https://doi.org/10.1016/j.jconrel.2014.03.057	https://doi.org/10.1016/j.jconrel.2014.03.057	VERB
admet-3065	954	2	[	[	X
admet-3065	954	3	145	145	NUM
admet-3065	954	4	]	]	X
admet-3065	954	5	g.t	g.t	PROPN
admet-3065	954	6	.	.	PROPN
admet-3065	954	7	noble	noble	PROPN
admet-3065	954	8	,	,	PUNCT
admet-3065	954	9	j.f	j.f	PROPN
admet-3065	954	10	.	.	PROPN
admet-3065	954	11	stefanick	stefanick	PROPN
admet-3065	954	12	,	,	PUNCT
admet-3065	954	13	j.d	j.d	PROPN
admet-3065	954	14	.	.	PROPN
admet-3065	954	15	ashley	ashley	PROPN
admet-3065	954	16	,	,	PUNCT
admet-3065	954	17	t.	t.	PROPN
admet-3065	954	18	kiziltepe	kiziltepe	NOUN
admet-3065	954	19	,	,	PUNCT
admet-3065	954	20	b.	b.	PROPN
admet-3065	954	21	bilgicer	bilgicer	PROPN
admet-3065	954	22	.	.	PUNCT
admet-3065	955	1	ligand	ligand	NOUN
admet-3065	955	2	-	-	PUNCT
admet-3065	955	3	targeted	target	VERB
admet-3065	955	4	liposome	liposome	NOUN
admet-3065	955	5	design	design	NOUN
admet-3065	955	6	:	:	PUNCT
admet-3065	955	7	challenges	challenge	NOUN
admet-3065	955	8	and	and	CCONJ
admet-3065	955	9	fundamental	fundamental	ADJ
admet-3065	955	10	considerations	consideration	NOUN
admet-3065	955	11	.	.	PUNCT
admet-3065	956	1	trends	trend	NOUN
admet-3065	956	2	in	in	ADP
admet-3065	956	3	biotechnology	biotechnology	NOUN
admet-3065	956	4	32	32	NUM
admet-3065	956	5	(	(	PUNCT
admet-3065	956	6	2014	2014	NUM
admet-3065	956	7	)	)	PUNCT
admet-3065	956	8	32	32	NUM
admet-3065	956	9	-	-	SYM
admet-3065	956	10	45	45	NUM
admet-3065	956	11	.	.	PUNCT
admet-3065	957	1	https://doi.org/10.1016/j.tibtech.2013.09.007	https://doi.org/10.1016/j.tibtech.2013.09.007	NUM
admet-3065	957	2	https://doi.org/10.1021/jm020233w	https://doi.org/10.1021/jm020233w	PROPN
admet-3065	957	3	https://doi.org/10.1016/j.jconrel.2012.04.002	https://doi.org/10.1016/j.jconrel.2012.04.002	PROPN
admet-3065	957	4	https://doi.org/10.3390/molecules26226786	https://doi.org/10.3390/molecules26226786	PROPN
admet-3065	957	5	https://doi.org/10.1021/j100270a040	https://doi.org/10.1021/j100270a040	PROPN
admet-3065	957	6	https://doi.org/10.3390/nano6040069	https://doi.org/10.3390/nano6040069	PROPN
admet-3065	957	7	https://doi.org/10.1016/j.jconrel.2014.03.009	https://doi.org/10.1016/j.jconrel.2014.03.009	PROPN
admet-3065	957	8	https://doi.org/10.1016/j.jconrel.2006.06.024	https://doi.org/10.1016/j.jconrel.2006.06.024	VERB
admet-3065	957	9	https://doi.org/10.1016/j.nano.2013.01.006	https://doi.org/10.1016/j.nano.2013.01.006	ADJ
admet-3065	957	10	https://doi.org/10.1021/jm060128c	https://doi.org/10.1021/jm060128c	ADJ
admet-3065	957	11	https://doi.org/10.1101/pdb.prot5583	https://doi.org/10.1101/pdb.prot5583	NOUN
admet-3065	957	12	https://doi.org/10.1038/srep07107	https://doi.org/10.1038/srep07107	VERB
admet-3065	957	13	https://doi.org/10.1021/mp800011e	https://doi.org/10.1021/mp800011e	PROPN
admet-3065	957	14	https://doi.org/10.1016/s0169-409x(99)00041-1	https://doi.org/10.1016/s0169-409x(99)00041-1	PROPN
admet-3065	957	15	https://doi.org/10.1038/nrd2614	https://doi.org/10.1038/nrd2614	PROPN
admet-3065	957	16	.	.	PUNCT
admet-3065	958	1	https://doi.org/10.1038/nrd2614	https://doi.org/10.1038/nrd2614	PROPN
admet-3065	958	2	https://doi.org/10.1016/j.jconrel.2016.11.015	https://doi.org/10.1016/j.jconrel.2016.11.015	PROPN
admet-3065	958	3	https://doi.org/10.1016/j.jconrel.2014.03.057	https://doi.org/10.1016/j.jconrel.2014.03.057	VERB
admet-3065	958	4	https://doi.org/10.1016/j.tibtech.2013.09.007	https://doi.org/10.1016/j.tibtech.2013.09.007	NUM
admet-3065	958	5	admet	admet	NOUN
admet-3065	958	6	&	&	CCONJ
admet-3065	958	7	dmpk	dmpk	PROPN
admet-3065	958	8	00(0	00(0	PROPN
admet-3065	958	9	)	)	PUNCT
admet-3065	958	10	(	(	PUNCT
admet-3065	958	11	2025	2025	NUM
admet-3065	958	12	)	)	PUNCT
admet-3065	958	13	3065	3065	NUM
admet-3065	958	14	liposome	liposome	NOUN
admet-3065	958	15	-	-	PUNCT
admet-3065	958	16	mediated	mediate	VERB
admet-3065	958	17	gene	gene	NOUN
admet-3065	958	18	delivery	delivery	NOUN
admet-3065	958	19	doi	doi	NOUN
admet-3065	958	20	:	:	PUNCT
admet-3065	958	21	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	958	22	27	27	NUM
admet-3065	959	1	[	[	X
admet-3065	959	2	146	146	NUM
admet-3065	959	3	]	]	X
admet-3065	959	4	f.	f.	PROPN
admet-3065	959	5	yuan	yuan	PROPN
admet-3065	959	6	,	,	PUNCT
admet-3065	959	7	m.	m.	PROPN
admet-3065	959	8	dellian	dellian	PROPN
admet-3065	959	9	,	,	PUNCT
admet-3065	959	10	d.	d.	PROPN
admet-3065	959	11	fukumura	fukumura	PROPN
admet-3065	959	12	,	,	PUNCT
admet-3065	959	13	m.	m.	NOUN
admet-3065	959	14	leunig	leunig	PROPN
admet-3065	959	15	,	,	PUNCT
admet-3065	959	16	d.a	d.a	PROPN
admet-3065	959	17	.	.	PROPN
admet-3065	959	18	berk	berk	PROPN
admet-3065	959	19	,	,	PUNCT
admet-3065	959	20	v.p	v.p	PROPN
admet-3065	959	21	.	.	PROPN
admet-3065	959	22	torchilin	torchilin	PROPN
admet-3065	959	23	,	,	PUNCT
admet-3065	959	24	r.k	r.k	PROPN
admet-3065	959	25	.	.	PROPN
admet-3065	959	26	jain	jain	PROPN
admet-3065	959	27	.	.	PUNCT
admet-3065	960	1	vascular	vascular	ADJ
admet-3065	960	2	permeability	permeability	NOUN
admet-3065	960	3	in	in	ADP
admet-3065	960	4	a	a	DET
admet-3065	960	5	human	human	ADJ
admet-3065	960	6	tumor	tumor	NOUN
admet-3065	960	7	xenograft	xenograft	NOUN
admet-3065	960	8	:	:	PUNCT
admet-3065	960	9	molecular	molecular	ADJ
admet-3065	960	10	size	size	NOUN
admet-3065	960	11	dependence	dependence	NOUN
admet-3065	960	12	and	and	CCONJ
admet-3065	960	13	cutoff	cutoff	NOUN
admet-3065	960	14	size	size	NOUN
admet-3065	960	15	.	.	PUNCT
admet-3065	961	1	cancer	cancer	NOUN
admet-3065	961	2	research	research	NOUN
admet-3065	961	3	55	55	NUM
admet-3065	961	4	(	(	PUNCT
admet-3065	961	5	1995	1995	NUM
admet-3065	961	6	)	)	PUNCT
admet-3065	961	7	3752	3752	NUM
admet-3065	961	8	-	-	SYM
admet-3065	961	9	3756	3756	NUM
admet-3065	961	10	.	.	PUNCT
admet-3065	962	1	https://doi.org/7641188	https://doi.org/7641188	PRON
admet-3065	962	2	[	[	X
admet-3065	962	3	147	147	NUM
admet-3065	962	4	]	]	PUNCT
admet-3065	962	5	s.	s.	PROPN
admet-3065	962	6	chen	chen	PROPN
admet-3065	962	7	,	,	PUNCT
admet-3065	962	8	j.	j.	PROPN
admet-3065	962	9	zheng	zheng	PROPN
admet-3065	962	10	,	,	PUNCT
admet-3065	962	11	l.	l.	PROPN
admet-3065	962	12	li	li	PROPN
admet-3065	962	13	,	,	PUNCT
admet-3065	962	14	s.	s.	PROPN
admet-3065	962	15	jiang	jiang	PROPN
admet-3065	962	16	.	.	PUNCT
admet-3065	963	1	strong	strong	ADJ
admet-3065	963	2	resistance	resistance	NOUN
admet-3065	963	3	of	of	ADP
admet-3065	963	4	phosphorylcholine	phosphorylcholine	ADJ
admet-3065	963	5	self	self	NOUN
admet-3065	963	6	-	-	PUNCT
admet-3065	963	7	assembled	assemble	VERB
admet-3065	963	8	monolayers	monolayer	NOUN
admet-3065	963	9	to	to	ADP
admet-3065	963	10	protein	protein	NOUN
admet-3065	963	11	adsorption	adsorption	NOUN
admet-3065	963	12	:	:	PUNCT
admet-3065	963	13	insights	insight	NOUN
admet-3065	963	14	into	into	ADP
admet-3065	963	15	nonfouling	nonfouling	NOUN
admet-3065	963	16	properties	property	NOUN
admet-3065	963	17	of	of	ADP
admet-3065	963	18	zwitterionic	zwitterionic	ADJ
admet-3065	963	19	materials	material	NOUN
admet-3065	963	20	.	.	PUNCT
admet-3065	964	1	journal	journal	NOUN
admet-3065	964	2	of	of	ADP
admet-3065	964	3	the	the	DET
admet-3065	964	4	american	american	PROPN
admet-3065	964	5	chemical	chemical	PROPN
admet-3065	964	6	society	society	PROPN
admet-3065	964	7	127	127	NUM
admet-3065	964	8	(	(	PUNCT
admet-3065	964	9	2005	2005	NUM
admet-3065	964	10	)	)	PUNCT
admet-3065	964	11	14473	14473	NUM
admet-3065	964	12	-	-	SYM
admet-3065	964	13	14478	14478	NUM
admet-3065	964	14	.	.	PUNCT
admet-3065	965	1	https://doi.org/10.1021/ja054169u	https://doi.org/10.1021/ja054169u	PROPN
admet-3065	966	1	[	[	X
admet-3065	966	2	148	148	NUM
admet-3065	966	3	]	]	X
admet-3065	966	4	j.b	j.b	PROPN
admet-3065	966	5	.	.	PUNCT
admet-3065	966	6	schlenoff	schlenoff	PROPN
admet-3065	966	7	.	.	PUNCT
admet-3065	967	1	zwitteration	zwitteration	NOUN
admet-3065	967	2	:	:	PUNCT
admet-3065	967	3	coating	coat	VERB
admet-3065	967	4	surfaces	surface	NOUN
admet-3065	967	5	with	with	ADP
admet-3065	967	6	zwitterionic	zwitterionic	ADJ
admet-3065	967	7	functionality	functionality	NOUN
admet-3065	967	8	to	to	PART
admet-3065	967	9	reduce	reduce	VERB
admet-3065	967	10	nonspecific	nonspecific	ADJ
admet-3065	967	11	adsorption	adsorption	NOUN
admet-3065	967	12	.	.	PUNCT
admet-3065	968	1	langmuir	langmuir	PROPN
admet-3065	968	2	30	30	NUM
admet-3065	968	3	(	(	PUNCT
admet-3065	968	4	2014	2014	NUM
admet-3065	968	5	)	)	PUNCT
admet-3065	968	6	9625	9625	NUM
admet-3065	968	7	-	-	SYM
admet-3065	968	8	9636	9636	NUM
admet-3065	968	9	.	.	PUNCT
admet-3065	969	1	https://doi.org/10.1021/la500057j	https://doi.org/10.1021/la500057j	X
admet-3065	970	1	[	[	X
admet-3065	970	2	149	149	NUM
admet-3065	970	3	]	]	X
admet-3065	970	4	n.s	n.s	PROPN
admet-3065	970	5	.	.	PROPN
admet-3065	970	6	templeton	templeton	PROPN
admet-3065	970	7	.	.	PUNCT
admet-3065	971	1	liposomal	liposomal	ADJ
admet-3065	971	2	delivery	delivery	NOUN
admet-3065	971	3	of	of	ADP
admet-3065	971	4	nucleic	nucleic	ADJ
admet-3065	971	5	acids	acid	NOUN
admet-3065	971	6	in	in	ADP
admet-3065	971	7	vivo	vivo	NOUN
admet-3065	971	8	.	.	PUNCT
admet-3065	972	1	dna	dna	NOUN
admet-3065	972	2	and	and	CCONJ
admet-3065	972	3	cell	cell	NOUN
admet-3065	972	4	biology	biology	NOUN
admet-3065	972	5	21	21	NUM
admet-3065	972	6	(	(	PUNCT
admet-3065	972	7	2002	2002	NUM
admet-3065	972	8	)	)	PUNCT
admet-3065	972	9	857	857	NUM
admet-3065	972	10	-	-	SYM
admet-3065	972	11	867	867	NUM
admet-3065	972	12	.	.	PUNCT
admet-3065	973	1	https://doi.org/10.1089/104454902762053828	https://doi.org/10.1089/104454902762053828	NOUN
admet-3065	974	1	[	[	X
admet-3065	974	2	150	150	NUM
admet-3065	974	3	]	]	X
admet-3065	974	4	a.j	a.j	PROPN
admet-3065	974	5	.	.	PROPN
admet-3065	974	6	sodt	sodt	PROPN
admet-3065	974	7	,	,	PUNCT
admet-3065	974	8	m.l	m.l	PROPN
admet-3065	974	9	.	.	PROPN
admet-3065	974	10	sandar	sandar	PROPN
admet-3065	974	11	,	,	PUNCT
admet-3065	974	12	k.	k.	PROPN
admet-3065	974	13	gawrisch	gawrisch	PROPN
admet-3065	974	14	,	,	PUNCT
admet-3065	974	15	r.w	r.w	PROPN
admet-3065	974	16	.	.	PROPN
admet-3065	974	17	pastor	pastor	PROPN
admet-3065	974	18	,	,	PUNCT
admet-3065	974	19	e.	e.	PROPN
admet-3065	974	20	lyman	lyman	PROPN
admet-3065	974	21	.	.	PUNCT
admet-3065	975	1	the	the	DET
admet-3065	975	2	molecular	molecular	ADJ
admet-3065	975	3	structure	structure	NOUN
admet-3065	975	4	of	of	ADP
admet-3065	975	5	the	the	DET
admet-3065	975	6	liquidordered	liquidordere	VERB
admet-3065	975	7	phase	phase	NOUN
admet-3065	975	8	of	of	ADP
admet-3065	975	9	lipid	lipid	ADJ
admet-3065	975	10	bilayers	bilayer	NOUN
admet-3065	975	11	.	.	PUNCT
admet-3065	976	1	journal	journal	NOUN
admet-3065	976	2	of	of	ADP
admet-3065	976	3	the	the	DET
admet-3065	976	4	american	american	PROPN
admet-3065	976	5	chemical	chemical	PROPN
admet-3065	976	6	society	society	PROPN
admet-3065	976	7	136	136	NUM
admet-3065	976	8	(	(	PUNCT
admet-3065	976	9	2014	2014	NUM
admet-3065	976	10	)	)	PUNCT
admet-3065	976	11	725	725	NUM
admet-3065	976	12	-	-	SYM
admet-3065	976	13	732	732	NUM
admet-3065	976	14	.	.	PUNCT
admet-3065	977	1	https://doi.org/10.1021/ja4105667	https://doi.org/10.1021/ja4105667	PRON
admet-3065	978	1	[	[	X
admet-3065	978	2	151	151	NUM
admet-3065	978	3	]	]	X
admet-3065	978	4	c.	c.	PROPN
admet-3065	978	5	liu	liu	PROPN
admet-3065	978	6	,	,	PUNCT
admet-3065	978	7	l.	l.	PROPN
admet-3065	978	8	zhang	zhang	PROPN
admet-3065	978	9	,	,	PUNCT
admet-3065	978	10	w.	w.	PROPN
admet-3065	978	11	zhu	zhu	PROPN
admet-3065	978	12	,	,	PUNCT
admet-3065	978	13	r.	r.	PROPN
admet-3065	978	14	guo	guo	PROPN
admet-3065	978	15	,	,	PUNCT
admet-3065	978	16	h.	h.	PROPN
admet-3065	978	17	sun	sun	PROPN
admet-3065	978	18	,	,	PUNCT
admet-3065	978	19	x.	x.	PROPN
admet-3065	978	20	chen	chen	PROPN
admet-3065	978	21	,	,	PUNCT
admet-3065	978	22	n.	n.	PROPN
admet-3065	978	23	deng	deng	PROPN
admet-3065	978	24	.	.	PUNCT
admet-3065	979	1	barriers	barrier	NOUN
admet-3065	979	2	and	and	CCONJ
admet-3065	979	3	strategies	strategy	NOUN
admet-3065	979	4	of	of	ADP
admet-3065	979	5	cationic	cationic	ADJ
admet-3065	979	6	liposomes	liposome	NOUN
admet-3065	979	7	for	for	ADP
admet-3065	979	8	cancer	cancer	NOUN
admet-3065	979	9	gene	gene	NOUN
admet-3065	979	10	therapy	therapy	NOUN
admet-3065	979	11	.	.	PUNCT
admet-3065	980	1	molecular	molecular	ADJ
admet-3065	980	2	therapy	therapy	NOUN
admet-3065	980	3	methods	method	NOUN
admet-3065	980	4	and	and	CCONJ
admet-3065	980	5	clinical	clinical	ADJ
admet-3065	980	6	development	development	NOUN
admet-3065	980	7	18	18	NUM
admet-3065	980	8	(	(	PUNCT
admet-3065	980	9	2020	2020	NUM
admet-3065	980	10	)	)	PUNCT
admet-3065	980	11	751	751	NUM
admet-3065	980	12	-	-	SYM
admet-3065	980	13	764	764	NUM
admet-3065	980	14	.	.	PUNCT
admet-3065	981	1	https://doi.org/10.1016/j.omtm.2020.07.015	https://doi.org/10.1016/j.omtm.2020.07.015	NUM
admet-3065	982	1	[	[	X
admet-3065	982	2	152	152	NUM
admet-3065	982	3	]	]	X
admet-3065	982	4	j.h	j.h	PROPN
admet-3065	982	5	.	.	PROPN
admet-3065	982	6	senior	senior	PROPN
admet-3065	982	7	,	,	PUNCT
admet-3065	982	8	k.r	k.r	PROPN
admet-3065	982	9	.	.	PROPN
admet-3065	982	10	trimble	trimble	PROPN
admet-3065	982	11	,	,	PUNCT
admet-3065	982	12	r.	r.	PROPN
admet-3065	982	13	maskiewicz	maskiewicz	PROPN
admet-3065	982	14	.	.	PUNCT
admet-3065	983	1	interaction	interaction	NOUN
admet-3065	983	2	of	of	ADP
admet-3065	983	3	positively	positively	ADV
admet-3065	983	4	-	-	PUNCT
admet-3065	983	5	charged	charge	VERB
admet-3065	983	6	liposomes	liposome	NOUN
admet-3065	983	7	with	with	ADP
admet-3065	983	8	blood	blood	NOUN
admet-3065	983	9	:	:	PUNCT
admet-3065	983	10	implications	implication	NOUN
admet-3065	983	11	for	for	ADP
admet-3065	983	12	their	their	PRON
admet-3065	983	13	application	application	NOUN
admet-3065	983	14	in	in	ADP
admet-3065	983	15	vivo	vivo	NOUN
admet-3065	983	16	.	.	PUNCT
admet-3065	984	1	bba	bba	PROPN
admet-3065	984	2	biomembranes	biomembrane	VERB
admet-3065	984	3	1070	1070	NUM
admet-3065	984	4	(	(	PUNCT
admet-3065	984	5	1991	1991	NUM
admet-3065	984	6	)	)	PUNCT
admet-3065	984	7	173	173	NUM
admet-3065	984	8	-	-	SYM
admet-3065	984	9	179	179	NUM
admet-3065	984	10	.	.	PUNCT
admet-3065	985	1	https://doi.org/10.1016/0005-2736(91)90160-a	https://doi.org/10.1016/0005-2736(91)90160-a	NOUN
admet-3065	985	2	[	[	X
admet-3065	985	3	153	153	NUM
admet-3065	985	4	]	]	X
admet-3065	985	5	y.	y.	PROPN
admet-3065	985	6	wang	wang	PROPN
admet-3065	985	7	,	,	PUNCT
admet-3065	985	8	l.	l.	PROPN
admet-3065	985	9	miao	miao	PROPN
admet-3065	985	10	,	,	PUNCT
admet-3065	985	11	a.	a.	NOUN
admet-3065	985	12	satterlee	satterlee	PROPN
admet-3065	985	13	,	,	PUNCT
admet-3065	985	14	l.	l.	PROPN
admet-3065	985	15	huang	huang	PROPN
admet-3065	985	16	.	.	PUNCT
admet-3065	986	1	delivery	delivery	NOUN
admet-3065	986	2	of	of	ADP
admet-3065	986	3	oligonucleotides	oligonucleotide	NOUN
admet-3065	986	4	with	with	ADP
admet-3065	986	5	lipid	lipid	ADJ
admet-3065	986	6	nanoparticles	nanoparticle	NOUN
admet-3065	986	7	.	.	PUNCT
admet-3065	987	1	advanced	advanced	ADJ
admet-3065	987	2	drug	drug	NOUN
admet-3065	987	3	delivery	delivery	NOUN
admet-3065	987	4	reviews	review	VERB
admet-3065	987	5	87	87	NUM
admet-3065	987	6	(	(	PUNCT
admet-3065	987	7	2015	2015	NUM
admet-3065	987	8	)	)	PUNCT
admet-3065	987	9	68	68	NUM
admet-3065	987	10	-	-	SYM
admet-3065	987	11	80	80	NUM
admet-3065	987	12	.	.	PUNCT
admet-3065	988	1	https://doi.org/10.1016/j.addr.2015.02.007	https://doi.org/10.1016/j.addr.2015.02.007	VERB
admet-3065	988	2	[	[	X
admet-3065	988	3	154	154	NUM
admet-3065	988	4	]	]	X
admet-3065	988	5	w.h	w.h	PROPN
admet-3065	988	6	.	.	PROPN
admet-3065	988	7	abuwatfa	abuwatfa	NOUN
admet-3065	988	8	,	,	PUNCT
admet-3065	988	9	n.s	n.s	PROPN
admet-3065	988	10	.	.	PROPN
admet-3065	988	11	awad	awad	PROPN
admet-3065	988	12	,	,	PUNCT
admet-3065	988	13	w.g	w.g	PROPN
admet-3065	988	14	.	.	PROPN
admet-3065	988	15	pitt	pitt	PROPN
admet-3065	988	16	,	,	PUNCT
admet-3065	988	17	g.a	g.a	PROPN
admet-3065	988	18	.	.	PROPN
admet-3065	988	19	husseini	husseini	PROPN
admet-3065	988	20	.	.	PROPN
admet-3065	988	21	thermosensitive	thermosensitive	ADJ
admet-3065	988	22	polymers	polymer	NOUN
admet-3065	988	23	and	and	CCONJ
admet-3065	988	24	thermoresponsive	thermoresponsive	ADJ
admet-3065	988	25	liposomal	liposomal	ADJ
admet-3065	988	26	drug	drug	NOUN
admet-3065	988	27	delivery	delivery	NOUN
admet-3065	988	28	systems	system	NOUN
admet-3065	988	29	.	.	PUNCT
admet-3065	989	1	polymers	polymer	NOUN
admet-3065	989	2	14	14	NUM
admet-3065	989	3	(	(	PUNCT
admet-3065	989	4	2022	2022	NUM
admet-3065	989	5	)	)	PUNCT
admet-3065	989	6	925	925	NUM
admet-3065	989	7	.	.	PUNCT
admet-3065	990	1	https://doi.org/10.3390/polym14050925	https://doi.org/10.3390/polym14050925	PROPN
admet-3065	990	2	[	[	X
admet-3065	990	3	155	155	NUM
admet-3065	990	4	]	]	X
admet-3065	990	5	m.y	m.y	PROPN
admet-3065	990	6	.	.	PROPN
admet-3065	990	7	zhuo	zhuo	PROPN
admet-3065	990	8	dai	dai	PROPN
admet-3065	990	9	,	,	PUNCT
admet-3065	990	10	x.	x.	PROPN
admet-3065	990	11	yi	yi	PROPN
admet-3065	990	12	,	,	PUNCT
admet-3065	990	13	z.	z.	PROPN
admet-3065	990	14	wu	wu	PROPN
admet-3065	990	15	,	,	PUNCT
admet-3065	990	16	f.	f.	PROPN
admet-3065	990	17	tian	tian	PROPN
admet-3065	990	18	,	,	PUNCT
admet-3065	990	19	y.	y.	PROPN
admet-3065	990	20	miao	miao	PROPN
admet-3065	990	21	,	,	PUNCT
admet-3065	990	22	w.	w.	NOUN
admet-3065	990	23	song	song	PROPN
admet-3065	990	24	,	,	PUNCT
admet-3065	990	25	s.	s.	PROPN
admet-3065	990	26	he	he	PRON
admet-3065	990	27	,	,	PUNCT
admet-3065	990	28	e.	e.	PROPN
admet-3065	990	29	ahmad	ahmad	PROPN
admet-3065	990	30	,	,	PUNCT
admet-3065	990	31	s.	s.	PROPN
admet-3065	990	32	guo	guo	PROPN
admet-3065	990	33	,	,	PUNCT
admet-3065	990	34	c.	c.	PROPN
admet-3065	990	35	zhu	zhu	PROPN
admet-3065	990	36	,	,	PUNCT
admet-3065	990	37	x.	x.	PROPN
admet-3065	990	38	zhang	zhang	PROPN
admet-3065	990	39	,	,	PUNCT
admet-3065	990	40	y.	y.	PROPN
admet-3065	990	41	li	li	PROPN
admet-3065	990	42	,	,	PUNCT
admet-3065	990	43	x.	x.	PROPN
admet-3065	990	44	shi	shi	PROPN
admet-3065	990	45	,	,	PUNCT
admet-3065	990	46	r.	r.	PROPN
admet-3065	990	47	wang	wang	PROPN
admet-3065	990	48	,	,	PUNCT
admet-3065	990	49	y.	y.	PROPN
admet-3065	990	50	gan	gan	PROPN
admet-3065	990	51	.	.	PUNCT
admet-3065	991	1	chain	chain	NOUN
admet-3065	991	2	-	-	PUNCT
admet-3065	991	3	lengthand	lengthand	NOUN
admet-3065	991	4	saturation	saturation	NOUN
admet-3065	991	5	-	-	PUNCT
admet-3065	991	6	tuned	tune	VERB
admet-3065	991	7	mechanics	mechanic	NOUN
admet-3065	991	8	of	of	ADP
admet-3065	991	9	fluid	fluid	ADJ
admet-3065	991	10	nanovesicles	nanovesicle	NOUN
admet-3065	991	11	direct	direct	ADJ
admet-3065	991	12	tumor	tumor	NOUN
admet-3065	991	13	delivery	delivery	NOUN
admet-3065	991	14	.	.	PUNCT
admet-3065	992	1	acs	acs	PROPN
admet-3065	992	2	nano	nano	VERB
admet-3065	992	3	13	13	NUM
admet-3065	992	4	(	(	PUNCT
admet-3065	992	5	2019	2019	NUM
admet-3065	992	6	)	)	PUNCT
admet-3065	992	7	7676	7676	NUM
admet-3065	992	8	-	-	SYM
admet-3065	992	9	7689	7689	NUM
admet-3065	992	10	.	.	PUNCT
admet-3065	993	1	https://doi.org/10.1021/acsnano.9b01181	https://doi.org/10.1021/acsnano.9b01181	PROPN
admet-3065	994	1	[	[	X
admet-3065	994	2	156	156	NUM
admet-3065	994	3	]	]	X
admet-3065	994	4	h.	h.	PROPN
admet-3065	994	5	abumanhal	abumanhal	PROPN
admet-3065	994	6	-	-	PUNCT
admet-3065	994	7	masarweh	masarweh	NOUN
admet-3065	994	8	,	,	PUNCT
admet-3065	994	9	d.	d.	PROPN
admet-3065	994	10	da	da	PROPN
admet-3065	994	11	silva	silva	PROPN
admet-3065	994	12	,	,	PUNCT
admet-3065	994	13	m.	m.	NOUN
admet-3065	994	14	poley	poley	PROPN
admet-3065	994	15	,	,	PUNCT
admet-3065	994	16	a.	a.	NOUN
admet-3065	994	17	zinger	zinger	PROPN
admet-3065	994	18	,	,	PUNCT
admet-3065	994	19	e.	e.	PROPN
admet-3065	994	20	goldman	goldman	PROPN
admet-3065	994	21	,	,	PUNCT
admet-3065	994	22	n.	n.	PROPN
admet-3065	994	23	krinsky	krinsky	PROPN
admet-3065	994	24	,	,	PUNCT
admet-3065	994	25	r.	r.	PROPN
admet-3065	994	26	kleiner	kleiner	PROPN
admet-3065	994	27	,	,	PUNCT
admet-3065	994	28	g.	g.	PROPN
admet-3065	994	29	shenbach	shenbach	PROPN
admet-3065	994	30	,	,	PUNCT
admet-3065	994	31	j.e	j.e	PROPN
admet-3065	994	32	.	.	PROPN
admet-3065	994	33	schroeder	schroeder	PROPN
admet-3065	994	34	,	,	PUNCT
admet-3065	994	35	j.	j.	PROPN
admet-3065	994	36	shklover	shklover	PROPN
admet-3065	994	37	.	.	PUNCT
admet-3065	995	1	tailoring	tailor	VERB
admet-3065	995	2	the	the	DET
admet-3065	995	3	lipid	lipid	NOUN
admet-3065	995	4	composition	composition	NOUN
admet-3065	995	5	of	of	ADP
admet-3065	995	6	nanoparticles	nanoparticle	NOUN
admet-3065	995	7	modulates	modulate	VERB
admet-3065	995	8	their	their	PRON
admet-3065	995	9	cellular	cellular	ADJ
admet-3065	995	10	uptake	uptake	NOUN
admet-3065	995	11	and	and	CCONJ
admet-3065	995	12	affects	affect	VERB
admet-3065	995	13	the	the	DET
admet-3065	995	14	viability	viability	NOUN
admet-3065	995	15	of	of	ADP
admet-3065	995	16	triple	triple	ADJ
admet-3065	995	17	negative	negative	ADJ
admet-3065	995	18	breast	breast	NOUN
admet-3065	995	19	cancer	cancer	NOUN
admet-3065	995	20	cells	cell	NOUN
admet-3065	995	21	.	.	PUNCT
admet-3065	996	1	journal	journal	PROPN
admet-3065	996	2	of	of	ADP
admet-3065	996	3	controlled	control	VERB
admet-3065	996	4	release	release	NOUN
admet-3065	996	5	307	307	NUM
admet-3065	996	6	(	(	PUNCT
admet-3065	996	7	2019	2019	NUM
admet-3065	996	8	)	)	PUNCT
admet-3065	996	9	331–341	331–341	NUM
admet-3065	996	10	.	.	PUNCT
admet-3065	997	1	https://doi.org/10.1016/j.jconrel.2019.06.025	https://doi.org/10.1016/j.jconrel.2019.06.025	PROPN
admet-3065	997	2	[	[	X
admet-3065	997	3	157	157	NUM
admet-3065	997	4	]	]	X
admet-3065	997	5	y.	y.	PROPN
admet-3065	997	6	liu	liu	PROPN
admet-3065	997	7	,	,	PUNCT
admet-3065	997	8	k.m	k.m	PROPN
admet-3065	997	9	.	.	PROPN
admet-3065	997	10	castro	castro	PROPN
admet-3065	997	11	bravo	bravo	PROPN
admet-3065	997	12	,	,	PUNCT
admet-3065	997	13	j.	j.	PROPN
admet-3065	997	14	liu	liu	PROPN
admet-3065	997	15	.	.	PUNCT
admet-3065	998	1	targeted	target	VERB
admet-3065	998	2	liposomal	liposomal	ADJ
admet-3065	998	3	drug	drug	NOUN
admet-3065	998	4	delivery	delivery	NOUN
admet-3065	998	5	:	:	PUNCT
admet-3065	998	6	a	a	DET
admet-3065	998	7	nanoscience	nanoscience	NOUN
admet-3065	998	8	and	and	CCONJ
admet-3065	998	9	biophysical	biophysical	ADJ
admet-3065	998	10	perspective	perspective	NOUN
admet-3065	998	11	.	.	PUNCT
admet-3065	999	1	nanoscale	nanoscale	NOUN
admet-3065	999	2	horizons	horizon	NOUN
admet-3065	999	3	6	6	NUM
admet-3065	999	4	(	(	PUNCT
admet-3065	999	5	2021	2021	NUM
admet-3065	999	6	)	)	PUNCT
admet-3065	999	7	78	78	NUM
admet-3065	999	8	-	-	SYM
admet-3065	999	9	94	94	NUM
admet-3065	999	10	.	.	PUNCT
admet-3065	1000	1	https://doi.org/10.1039/d0nh00605j	https://doi.org/10.1039/d0nh00605j	X
admet-3065	1001	1	[	[	X
admet-3065	1001	2	158	158	X
admet-3065	1001	3	]	]	X
admet-3065	1001	4	p.	p.	NOUN
admet-3065	1001	5	fu	fu	PROPN
admet-3065	1001	6	,	,	PUNCT
admet-3065	1001	7	j.	j.	PROPN
admet-3065	1001	8	zhang	zhang	PROPN
admet-3065	1001	9	,	,	PUNCT
admet-3065	1001	10	h.	h.	PROPN
admet-3065	1001	11	li	li	PROPN
admet-3065	1001	12	,	,	PUNCT
admet-3065	1001	13	m.	m.	PROPN
admet-3065	1001	14	mak	mak	PROPN
admet-3065	1001	15	,	,	PUNCT
admet-3065	1001	16	w.	w.	PROPN
admet-3065	1001	17	xu	xu	PROPN
admet-3065	1001	18	,	,	PUNCT
admet-3065	1001	19	z.	z.	PROPN
admet-3065	1001	20	tao	tao	PROPN
admet-3065	1001	21	.	.	PUNCT
admet-3065	1002	1	extracellular	extracellular	ADJ
admet-3065	1002	2	vesicles	vesicle	NOUN
admet-3065	1002	3	as	as	ADP
admet-3065	1002	4	delivery	delivery	NOUN
admet-3065	1002	5	systems	system	NOUN
admet-3065	1002	6	at	at	ADP
admet-3065	1002	7	nano-/microscale	nano-/microscale	NUM
admet-3065	1002	8	.	.	PUNCT
admet-3065	1003	1	advanced	advanced	ADJ
admet-3065	1003	2	drug	drug	NOUN
admet-3065	1003	3	delivery	delivery	NOUN
admet-3065	1003	4	reviews	review	VERB
admet-3065	1003	5	179	179	NUM
admet-3065	1003	6	(	(	PUNCT
admet-3065	1003	7	2021	2021	NUM
admet-3065	1003	8	)	)	PUNCT
admet-3065	1003	9	113910	113910	NUM
admet-3065	1003	10	.	.	PUNCT
admet-3065	1004	1	https://doi.org/10.1016/j.addr.2021.113910	https://doi.org/10.1016/j.addr.2021.113910	NOUN
admet-3065	1004	2	[	[	X
admet-3065	1004	3	159	159	NUM
admet-3065	1004	4	]	]	X
admet-3065	1004	5	l.v	l.v	PROPN
admet-3065	1004	6	.	.	PROPN
admet-3065	1004	7	chernomordik	chernomordik	PROPN
admet-3065	1004	8	,	,	PUNCT
admet-3065	1004	9	m.m	m.m	PROPN
admet-3065	1004	10	.	.	PROPN
admet-3065	1004	11	kozlov	kozlov	PROPN
admet-3065	1004	12	.	.	PUNCT
admet-3065	1005	1	mechanics	mechanic	NOUN
admet-3065	1005	2	of	of	ADP
admet-3065	1005	3	membrane	membrane	NOUN
admet-3065	1005	4	fusion	fusion	NOUN
admet-3065	1005	5	.	.	PUNCT
admet-3065	1006	1	nature	nature	NOUN
admet-3065	1006	2	structural	structural	ADJ
admet-3065	1006	3	and	and	CCONJ
admet-3065	1006	4	molecular	molecular	ADJ
admet-3065	1006	5	biology	biology	NOUN
admet-3065	1006	6	15	15	NUM
admet-3065	1006	7	(	(	PUNCT
admet-3065	1006	8	2008	2008	NUM
admet-3065	1006	9	)	)	PUNCT
admet-3065	1006	10	675	675	NUM
admet-3065	1006	11	-	-	SYM
admet-3065	1006	12	683	683	NUM
admet-3065	1006	13	.	.	PUNCT
admet-3065	1007	1	https://doi.org/10.1038/nsmb.1455;kwrd	https://doi.org/10.1038/nsmb.1455;kwrd	PROPN
admet-3065	1008	1	[	[	X
admet-3065	1008	2	160	160	NUM
admet-3065	1008	3	]	]	PUNCT
admet-3065	1008	4	s.	s.	PROPN
admet-3065	1008	5	ohki	ohki	PROPN
admet-3065	1008	6	,	,	PUNCT
admet-3065	1008	7	y.	y.	PROPN
admet-3065	1008	8	takato	takato	PROPN
admet-3065	1008	9	.	.	PUNCT
admet-3065	1009	1	a	a	DET
admet-3065	1009	2	molecular	molecular	ADJ
admet-3065	1009	3	mechanism	mechanism	NOUN
admet-3065	1009	4	of	of	ADP
admet-3065	1009	5	lipid	lipid	ADJ
admet-3065	1009	6	membrane	membrane	NOUN
admet-3065	1009	7	fusion	fusion	NOUN
admet-3065	1009	8	.	.	PUNCT
admet-3065	1010	1	biophysical	biophysical	ADJ
admet-3065	1010	2	journal	journal	NOUN
admet-3065	1010	3	104	104	NUM
admet-3065	1010	4	(	(	PUNCT
admet-3065	1010	5	2013	2013	NUM
admet-3065	1010	6	)	)	PUNCT
admet-3065	1010	7	92	92	NUM
admet-3065	1010	8	.	.	PUNCT
admet-3065	1011	1	https://doi.org/10.1016/j.bpj.2012.11.550	https://doi.org/10.1016/j.bpj.2012.11.550	PROPN
admet-3065	1012	1	[	[	X
admet-3065	1012	2	161	161	NUM
admet-3065	1012	3	]	]	PUNCT
admet-3065	1012	4	j.	j.	PROPN
admet-3065	1012	5	yang	yang	PROPN
admet-3065	1012	6	,	,	PUNCT
admet-3065	1012	7	y.	y.	PROPN
admet-3065	1012	8	shimada	shimada	PROPN
admet-3065	1012	9	,	,	PUNCT
admet-3065	1012	10	r.c	r.c	PROPN
admet-3065	1012	11	.	.	PROPN
admet-3065	1012	12	olsthoorn	olsthoorn	PROPN
admet-3065	1012	13	,	,	PUNCT
admet-3065	1012	14	b.e	b.e	PROPN
admet-3065	1012	15	.	.	PROPN
admet-3065	1012	16	snaar	snaar	NOUN
admet-3065	1012	17	-	-	PUNCT
admet-3065	1012	18	jagalska	jagalska	NOUN
admet-3065	1012	19	,	,	PUNCT
admet-3065	1012	20	h.p	h.p	PROPN
admet-3065	1012	21	.	.	PROPN
admet-3065	1012	22	spaink	spaink	PROPN
admet-3065	1012	23	,	,	PUNCT
admet-3065	1012	24	a.	a.	PROPN
admet-3065	1012	25	kros	kros	PROPN
admet-3065	1012	26	.	.	PUNCT
admet-3065	1013	1	application	application	NOUN
admet-3065	1013	2	of	of	ADP
admet-3065	1013	3	coiled	coil	VERB
admet-3065	1013	4	coil	coil	NOUN
admet-3065	1013	5	peptides	peptide	NOUN
admet-3065	1013	6	in	in	ADP
admet-3065	1013	7	liposomal	liposomal	ADJ
admet-3065	1013	8	anticancer	anticancer	NOUN
admet-3065	1013	9	drug	drug	NOUN
admet-3065	1013	10	delivery	delivery	NOUN
admet-3065	1013	11	using	use	VERB
admet-3065	1013	12	a	a	DET
admet-3065	1013	13	zebrafish	zebrafish	ADJ
admet-3065	1013	14	xenograft	xenograft	NOUN
admet-3065	1013	15	model	model	PROPN
admet-3065	1013	16	.	.	PUNCT
admet-3065	1014	1	acs	acs	PROPN
admet-3065	1014	2	nano	nano	VERB
admet-3065	1014	3	10	10	NUM
admet-3065	1014	4	(	(	PUNCT
admet-3065	1014	5	2016	2016	NUM
admet-3065	1014	6	)	)	PUNCT
admet-3065	1014	7	7428–7435	7428–7435	NUM
admet-3065	1014	8	.	.	PUNCT
admet-3065	1015	1	https://doi.org/10.1021/acsnano.6b01410	https://doi.org/10.1021/acsnano.6b01410	NOUN
admet-3065	1016	1	[	[	X
admet-3065	1016	2	162	162	NUM
admet-3065	1016	3	]	]	X
admet-3065	1016	4	y.	y.	PROPN
admet-3065	1016	5	zeng	zeng	PROPN
admet-3065	1016	6	,	,	PUNCT
admet-3065	1016	7	m.	m.	PROPN
admet-3065	1016	8	shen	shen	PROPN
admet-3065	1016	9	,	,	PUNCT
admet-3065	1016	10	a.	a.	PROPN
admet-3065	1016	11	singhal	singhal	PROPN
admet-3065	1016	12	,	,	PUNCT
admet-3065	1016	13	g.j.a	g.j.a	ADJ
admet-3065	1016	14	.	.	PUNCT
admet-3065	1017	1	sevink	sevink	PROPN
admet-3065	1017	2	,	,	PUNCT
admet-3065	1017	3	n.	n.	NOUN
admet-3065	1017	4	crone	crone	NOUN
admet-3065	1017	5	,	,	PUNCT
admet-3065	1017	6	a.l	a.l	PROPN
admet-3065	1017	7	.	.	PROPN
admet-3065	1017	8	boyle	boyle	PROPN
admet-3065	1017	9	,	,	PUNCT
admet-3065	1017	10	a.	a.	PROPN
admet-3065	1017	11	kros	kros	PROPN
admet-3065	1017	12	.	.	PUNCT
admet-3065	1018	1	enhanced	enhance	VERB
admet-3065	1018	2	liposomal	liposomal	ADJ
admet-3065	1018	3	drug	drug	NOUN
admet-3065	1018	4	delivery	delivery	NOUN
admet-3065	1018	5	via	via	ADP
admet-3065	1018	6	membrane	membrane	NOUN
admet-3065	1018	7	fusion	fusion	NOUN
admet-3065	1018	8	triggered	trigger	VERB
admet-3065	1018	9	by	by	ADP
admet-3065	1018	10	dimeric	dimeric	ADJ
admet-3065	1018	11	coiled	coil	VERB
admet-3065	1018	12	-	-	PUNCT
admet-3065	1018	13	coil	coil	NOUN
admet-3065	1018	14	peptides	peptide	NOUN
admet-3065	1018	15	.	.	PUNCT
admet-3065	1019	1	small	small	ADJ
admet-3065	1019	2	19	19	NUM
admet-3065	1019	3	(	(	PUNCT
admet-3065	1019	4	2023	2023	NUM
admet-3065	1019	5	)	)	PUNCT
admet-3065	1019	6	2301133	2301133	NUM
admet-3065	1019	7	.	.	PUNCT
admet-3065	1020	1	https://doi.org/10.1002/smll.202301133	https://doi.org/10.1002/smll.202301133	PRON
admet-3065	1021	1	[	[	X
admet-3065	1021	2	163	163	NUM
admet-3065	1021	3	]	]	X
admet-3065	1021	4	a.n	a.n	PROPN
admet-3065	1021	5	.	.	PROPN
admet-3065	1021	6	trementozzi	trementozzi	PROPN
admet-3065	1021	7	,	,	PUNCT
admet-3065	1021	8	z.i	z.i	PROPN
admet-3065	1021	9	.	.	PROPN
admet-3065	1021	10	imam	imam	PROPN
admet-3065	1021	11	,	,	PUNCT
admet-3065	1021	12	m.	m.	NOUN
admet-3065	1021	13	mendicino	mendicino	PROPN
admet-3065	1021	14	,	,	PUNCT
admet-3065	1021	15	c.c	c.c	PROPN
admet-3065	1021	16	.	.	PROPN
admet-3065	1021	17	hayden	hayden	PROPN
admet-3065	1021	18	,	,	PUNCT
admet-3065	1021	19	j.c	j.c	PROPN
admet-3065	1021	20	.	.	PROPN
admet-3065	1021	21	stachowiak	stachowiak	PROPN
admet-3065	1021	22	.	.	PUNCT
admet-3065	1021	23	liposome	liposome	NOUN
admet-3065	1021	24	-	-	PUNCT
admet-3065	1021	25	mediated	mediate	VERB
admet-3065	1021	26	chemotherapeutic	chemotherapeutic	ADJ
admet-3065	1021	27	delivery	delivery	NOUN
admet-3065	1021	28	is	be	AUX
admet-3065	1021	29	synergistically	synergistically	ADV
admet-3065	1021	30	enhanced	enhance	VERB
admet-3065	1021	31	by	by	ADP
admet-3065	1021	32	ternary	ternary	ADJ
admet-3065	1021	33	lipid	lipid	NOUN
admet-3065	1021	34	compositions	composition	NOUN
admet-3065	1021	35	and	and	CCONJ
admet-3065	1021	36	cationic	cationic	ADJ
admet-3065	1021	37	lipids	lipid	NOUN
admet-3065	1021	38	.	.	PUNCT
admet-3065	1022	1	langmuir	langmuir	PROPN
admet-3065	1022	2	35	35	NUM
admet-3065	1022	3	(	(	PUNCT
admet-3065	1022	4	2019	2019	NUM
admet-3065	1022	5	)	)	PUNCT
admet-3065	1022	6	12532	12532	NUM
admet-3065	1022	7	-	-	SYM
admet-3065	1022	8	12542	12542	NUM
admet-3065	1022	9	.	.	PUNCT
admet-3065	1023	1	https://doi.org/10.1021/acs.langmuir.9b01965	https://doi.org/10.1021/acs.langmuir.9b01965	NOUN
admet-3065	1023	2	https://doi.org/7641188	https://doi.org/7641188	PROPN
admet-3065	1023	3	https://doi.org/10.1021/ja054169u	https://doi.org/10.1021/ja054169u	PROPN
admet-3065	1023	4	https://doi.org/10.1021/la500057j	https://doi.org/10.1021/la500057j	PROPN
admet-3065	1023	5	https://doi.org/10.1089/104454902762053828	https://doi.org/10.1089/104454902762053828	NOUN
admet-3065	1023	6	https://doi.org/10.1021/ja4105667	https://doi.org/10.1021/ja4105667	ADP
admet-3065	1023	7	https://doi.org/10.1016/j.omtm.2020.07.015	https://doi.org/10.1016/j.omtm.2020.07.015	NUM
admet-3065	1023	8	https://doi.org/10.1016/0005-2736(91)90160-a	https://doi.org/10.1016/0005-2736(91)90160-a	NOUN
admet-3065	1023	9	https://doi.org/10.1016/j.addr.2015.02.007	https://doi.org/10.1016/j.addr.2015.02.007	VERB
admet-3065	1023	10	https://doi.org/10.3390/polym14050925	https://doi.org/10.3390/polym14050925	PROPN
admet-3065	1023	11	https://doi.org/10.1021/acsnano.9b01181	https://doi.org/10.1021/acsnano.9b01181	PROPN
admet-3065	1023	12	https://doi.org/10.1016/j.jconrel.2019.06.025	https://doi.org/10.1016/j.jconrel.2019.06.025	VERB
admet-3065	1023	13	https://doi.org/10.1039/d0nh00605j	https://doi.org/10.1039/d0nh00605j	PROPN
admet-3065	1023	14	https://doi.org/10.1016/j.addr.2021.113910	https://doi.org/10.1016/j.addr.2021.113910	PROPN
admet-3065	1023	15	https://doi.org/10.1038/nsmb.1455;kwrd	https://doi.org/10.1038/nsmb.1455;kwrd	PROPN
admet-3065	1023	16	https://doi.org/10.1016/j.bpj.2012.11.550	https://doi.org/10.1016/j.bpj.2012.11.550	PROPN
admet-3065	1023	17	https://doi.org/10.1021/acsnano.6b01410	https://doi.org/10.1021/acsnano.6b01410	PROPN
admet-3065	1023	18	https://doi.org/10.1002/smll.202301133	https://doi.org/10.1002/smll.202301133	PRON
admet-3065	1023	19	https://doi.org/10.1021/acs.langmuir.9b01965	https://doi.org/10.1021/acs.langmuir.9b01965	PROPN
admet-3065	1024	1	e.	e.	PROPN
admet-3065	1024	2	j.	j.	PROPN
admet-3065	1024	3	saleh	saleh	PROPN
admet-3065	1024	4	et	et	PROPN
admet-3065	1024	5	al	al	PROPN
admet-3065	1024	6	.	.	PROPN
admet-3065	1024	7	admet	admet	PROPN
admet-3065	1024	8	&	&	CCONJ
admet-3065	1024	9	dmpk	dmpk	PROPN
admet-3065	1024	10	00(0	00(0	PROPN
admet-3065	1024	11	)	)	PUNCT
admet-3065	1024	12	(	(	PUNCT
admet-3065	1024	13	2025	2025	NUM
admet-3065	1024	14	)	)	PUNCT
admet-3065	1024	15	3065	3065	NUM
admet-3065	1024	16	28	28	NUM
admet-3065	1025	1	[	[	X
admet-3065	1025	2	164	164	NUM
admet-3065	1025	3	]	]	X
admet-3065	1025	4	a.l	a.l	PROPN
admet-3065	1025	5	.	.	PROPN
admet-3065	1025	6	klibanov	klibanov	PROPN
admet-3065	1025	7	,	,	PUNCT
admet-3065	1025	8	k.	k.	PROPN
admet-3065	1025	9	maruyama	maruyama	PROPN
admet-3065	1025	10	,	,	PUNCT
admet-3065	1025	11	v.p	v.p	PROPN
admet-3065	1025	12	.	.	PROPN
admet-3065	1025	13	torchilin	torchilin	PROPN
admet-3065	1025	14	,	,	PUNCT
admet-3065	1025	15	l.	l.	PROPN
admet-3065	1025	16	huang	huang	PROPN
admet-3065	1025	17	.	.	PROPN
admet-3065	1026	1	amphipathic	amphipathic	PROPN
admet-3065	1026	2	polyethyleneglycols	polyethyleneglycol	NOUN
admet-3065	1026	3	effectively	effectively	ADV
admet-3065	1026	4	prolong	prolong	VERB
admet-3065	1026	5	the	the	DET
admet-3065	1026	6	circulation	circulation	NOUN
admet-3065	1026	7	time	time	NOUN
admet-3065	1026	8	of	of	ADP
admet-3065	1026	9	liposomes	liposome	NOUN
admet-3065	1026	10	.	.	PUNCT
admet-3065	1027	1	febs	febs	NOUN
admet-3065	1027	2	letters	letter	NOUN
admet-3065	1027	3	268	268	NUM
admet-3065	1027	4	(	(	PUNCT
admet-3065	1027	5	1990	1990	NUM
admet-3065	1027	6	)	)	PUNCT
admet-3065	1027	7	235	235	NUM
admet-3065	1027	8	-	-	SYM
admet-3065	1027	9	237	237	NUM
admet-3065	1027	10	.	.	PUNCT
admet-3065	1028	1	https://doi.org/10.1016/0014-5793(90)81016-h	https://doi.org/10.1016/0014-5793(90)81016-h	PROPN
admet-3065	1029	1	[	[	X
admet-3065	1029	2	165	165	NUM
admet-3065	1029	3	]	]	PUNCT
admet-3065	1029	4	k.	k.	PROPN
admet-3065	1029	5	abe	abe	PROPN
admet-3065	1029	6	,	,	PUNCT
admet-3065	1029	7	k.	k.	PROPN
admet-3065	1029	8	higashi	higashi	PROPN
admet-3065	1029	9	,	,	PUNCT
admet-3065	1029	10	k.	k.	PROPN
admet-3065	1029	11	watabe	watabe	PROPN
admet-3065	1029	12	,	,	PUNCT
admet-3065	1029	13	a.	a.	PROPN
admet-3065	1029	14	kobayashi	kobayashi	PROPN
admet-3065	1029	15	,	,	PUNCT
admet-3065	1029	16	w.	w.	PROPN
admet-3065	1029	17	limwikrant	limwikrant	PROPN
admet-3065	1029	18	,	,	PUNCT
admet-3065	1029	19	k.	k.	PROPN
admet-3065	1029	20	yamamoto	yamamoto	PROPN
admet-3065	1029	21	,	,	PUNCT
admet-3065	1029	22	k.	k.	PROPN
admet-3065	1029	23	moribe	moribe	PROPN
admet-3065	1029	24	.	.	PUNCT
admet-3065	1030	1	effects	effect	NOUN
admet-3065	1030	2	of	of	ADP
admet-3065	1030	3	the	the	DET
admet-3065	1030	4	peg	peg	NOUN
admet-3065	1030	5	molecular	molecular	ADJ
admet-3065	1030	6	weight	weight	NOUN
admet-3065	1030	7	of	of	ADP
admet-3065	1030	8	a	a	DET
admet-3065	1030	9	peg	peg	NOUN
admet-3065	1030	10	-	-	PUNCT
admet-3065	1030	11	lipid	lipid	NOUN
admet-3065	1030	12	and	and	CCONJ
admet-3065	1030	13	cholesterol	cholesterol	NOUN
admet-3065	1030	14	on	on	ADP
admet-3065	1030	15	peg	peg	NOUN
admet-3065	1030	16	chain	chain	NOUN
admet-3065	1030	17	flexibility	flexibility	NOUN
admet-3065	1030	18	on	on	ADP
admet-3065	1030	19	liposome	liposome	NOUN
admet-3065	1030	20	surfaces	surface	NOUN
admet-3065	1030	21	.	.	PUNCT
admet-3065	1031	1	colloids	colloid	NOUN
admet-3065	1031	2	and	and	CCONJ
admet-3065	1031	3	surfaces	surface	NOUN
admet-3065	1031	4	a	a	DET
admet-3065	1031	5	:	:	PUNCT
admet-3065	1031	6	physicochemical	physicochemical	ADJ
admet-3065	1031	7	and	and	CCONJ
admet-3065	1031	8	engineering	engineering	NOUN
admet-3065	1031	9	aspects	aspect	NOUN
admet-3065	1031	10	474	474	NUM
admet-3065	1031	11	(	(	PUNCT
admet-3065	1031	12	2015	2015	NUM
admet-3065	1031	13	)	)	PUNCT
admet-3065	1031	14	63	63	NUM
admet-3065	1031	15	-	-	SYM
admet-3065	1031	16	70	70	NUM
admet-3065	1031	17	.	.	PUNCT
admet-3065	1032	1	https://doi.org/10.1016/j.colsurfa.2015.03.006	https://doi.org/10.1016/j.colsurfa.2015.03.006	NOUN
admet-3065	1032	2	[	[	X
admet-3065	1032	3	166	166	NUM
admet-3065	1032	4	]	]	X
admet-3065	1032	5	d.	d.	PROPN
admet-3065	1032	6	hoekstra	hoekstra	PROPN
admet-3065	1032	7	,	,	PUNCT
admet-3065	1032	8	j.	j.	PROPN
admet-3065	1032	9	rejman	rejman	PROPN
admet-3065	1032	10	,	,	PUNCT
admet-3065	1032	11	l.	l.	PROPN
admet-3065	1032	12	wasungu	wasungu	PROPN
admet-3065	1032	13	,	,	PUNCT
admet-3065	1032	14	f.	f.	PROPN
admet-3065	1032	15	shi	shi	PROPN
admet-3065	1032	16	,	,	PUNCT
admet-3065	1032	17	i.	i.	PROPN
admet-3065	1032	18	zuhorn	zuhorn	PROPN
admet-3065	1032	19	.	.	PUNCT
admet-3065	1033	1	gene	gene	NOUN
admet-3065	1033	2	delivery	delivery	NOUN
admet-3065	1033	3	by	by	ADP
admet-3065	1033	4	cationic	cationic	ADJ
admet-3065	1033	5	lipids	lipid	NOUN
admet-3065	1033	6	:	:	PUNCT
admet-3065	1033	7	in	in	ADP
admet-3065	1033	8	and	and	CCONJ
admet-3065	1033	9	out	out	ADP
admet-3065	1033	10	of	of	ADP
admet-3065	1033	11	an	an	DET
admet-3065	1033	12	endosome	endosome	NOUN
admet-3065	1033	13	.	.	PUNCT
admet-3065	1034	1	biochemical	biochemical	ADJ
admet-3065	1034	2	society	society	NOUN
admet-3065	1034	3	transactions	transaction	NOUN
admet-3065	1034	4	35	35	NUM
admet-3065	1034	5	(	(	PUNCT
admet-3065	1034	6	2007	2007	NUM
admet-3065	1034	7	)	)	PUNCT
admet-3065	1034	8	68	68	NUM
admet-3065	1034	9	-	-	SYM
admet-3065	1034	10	71	71	NUM
admet-3065	1034	11	.	.	PUNCT
admet-3065	1035	1	https://doi.org/10.1042/bst0350068	https://doi.org/10.1042/bst0350068	PRON
admet-3065	1035	2	[	[	X
admet-3065	1035	3	167	167	NUM
admet-3065	1035	4	]	]	X
admet-3065	1035	5	a.h	a.h	PROPN
admet-3065	1035	6	.	.	PROPN
admet-3065	1035	7	baker	baker	PROPN
admet-3065	1035	8	,	,	PUNCT
admet-3065	1035	9	a.	a.	PROPN
admet-3065	1035	10	kritz	kritz	PROPN
admet-3065	1035	11	,	,	PUNCT
admet-3065	1035	12	l.m	l.m	PROPN
admet-3065	1035	13	.	.	PROPN
admet-3065	1035	14	work	work	PROPN
admet-3065	1035	15	,	,	PUNCT
admet-3065	1035	16	s.a	s.a	PROPN
admet-3065	1035	17	.	.	PROPN
admet-3065	1035	18	nicklin	nicklin	PROPN
admet-3065	1035	19	.	.	PUNCT
admet-3065	1036	1	cell	cell	NOUN
admet-3065	1036	2	-	-	PUNCT
admet-3065	1036	3	selective	selective	ADJ
admet-3065	1036	4	viral	viral	ADJ
admet-3065	1036	5	gene	gene	NOUN
admet-3065	1036	6	delivery	delivery	NOUN
admet-3065	1036	7	vectors	vector	NOUN
admet-3065	1036	8	for	for	ADP
admet-3065	1036	9	the	the	DET
admet-3065	1036	10	vasculature	vasculature	NOUN
admet-3065	1036	11	.	.	PUNCT
admet-3065	1037	1	experimental	experimental	ADJ
admet-3065	1037	2	physiology	physiology	NOUN
admet-3065	1037	3	90	90	NUM
admet-3065	1037	4	(	(	PUNCT
admet-3065	1037	5	2005	2005	NUM
admet-3065	1037	6	)	)	PUNCT
admet-3065	1037	7	27	27	NUM
admet-3065	1037	8	-	-	SYM
admet-3065	1037	9	31	31	NUM
admet-3065	1037	10	.	.	PUNCT
admet-3065	1038	1	https://doi.org/10.1113/expphysiol.2004.028126	https://doi.org/10.1113/expphysiol.2004.028126	NOUN
admet-3065	1039	1	[	[	X
admet-3065	1039	2	168	168	NUM
admet-3065	1039	3	]	]	X
admet-3065	1039	4	y.q	y.q	PROPN
admet-3065	1039	5	.	.	PROPN
admet-3065	1039	6	zhang	zhang	PROPN
admet-3065	1039	7	,	,	PUNCT
admet-3065	1039	8	r.r	r.r	PROPN
admet-3065	1039	9	.	.	PROPN
admet-3065	1039	10	guo	guo	PROPN
admet-3065	1039	11	,	,	PUNCT
admet-3065	1039	12	y.h	y.h	PROPN
admet-3065	1039	13	.	.	PROPN
admet-3065	1039	14	chen	chen	PROPN
admet-3065	1039	15	,	,	PUNCT
admet-3065	1039	16	t.c	t.c	PROPN
admet-3065	1039	17	.	.	PROPN
admet-3065	1039	18	li	li	PROPN
admet-3065	1039	19	,	,	PUNCT
admet-3065	1039	20	w.z	w.z	PROPN
admet-3065	1039	21	.	.	PROPN
admet-3065	1039	22	du	du	PROPN
admet-3065	1039	23	,	,	PUNCT
admet-3065	1039	24	r.w	r.w	PROPN
admet-3065	1039	25	.	.	PROPN
admet-3065	1039	26	xiang	xiang	PROPN
admet-3065	1039	27	,	,	PUNCT
admet-3065	1039	28	j.b	j.b	PROPN
admet-3065	1039	29	.	.	PUNCT
admet-3065	1040	1	guan	guan	PROPN
admet-3065	1040	2	,	,	PUNCT
admet-3065	1040	3	y.p	y.p	PROPN
admet-3065	1040	4	.	.	PROPN
admet-3065	1040	5	li	li	PROPN
admet-3065	1040	6	,	,	PUNCT
admet-3065	1040	7	y.y	y.y	PROPN
admet-3065	1040	8	.	.	PROPN
admet-3065	1040	9	huang	huang	PROPN
admet-3065	1040	10	,	,	PUNCT
admet-3065	1040	11	z.q	z.q	PROPN
admet-3065	1040	12	.	.	PROPN
admet-3065	1040	13	yu	yu	PROPN
admet-3065	1040	14	,	,	PUNCT
admet-3065	1040	15	y.	y.	PROPN
admet-3065	1040	16	cai	cai	PROPN
admet-3065	1040	17	,	,	PUNCT
admet-3065	1040	18	p.	p.	PROPN
admet-3065	1040	19	zhang	zhang	PROPN
admet-3065	1040	20	,	,	PUNCT
admet-3065	1040	21	g.x	g.x	PROPN
admet-3065	1040	22	.	.	PROPN
admet-3065	1040	23	ling	ling	PROPN
admet-3065	1040	24	.	.	PUNCT
admet-3065	1041	1	ionizable	ionizable	ADJ
admet-3065	1041	2	drug	drug	NOUN
admet-3065	1041	3	delivery	delivery	NOUN
admet-3065	1041	4	systems	system	NOUN
admet-3065	1041	5	for	for	ADP
admet-3065	1041	6	efficient	efficient	ADJ
admet-3065	1041	7	and	and	CCONJ
admet-3065	1041	8	selective	selective	ADJ
admet-3065	1041	9	gene	gene	NOUN
admet-3065	1041	10	therapy	therapy	NOUN
admet-3065	1041	11	.	.	PUNCT
admet-3065	1042	1	military	military	ADJ
admet-3065	1042	2	medical	medical	ADJ
admet-3065	1042	3	research	research	NOUN
admet-3065	1042	4	10	10	NUM
admet-3065	1042	5	(	(	PUNCT
admet-3065	1042	6	2023	2023	NUM
admet-3065	1042	7	)	)	PUNCT
admet-3065	1042	8	1	1	NUM
admet-3065	1042	9	-	-	SYM
admet-3065	1042	10	29	29	NUM
admet-3065	1042	11	.	.	PUNCT
admet-3065	1043	1	https://doi.org/10.1186/s40779-023-00445-z	https://doi.org/10.1186/s40779-023-00445-z	PRON
admet-3065	1044	1	[	[	X
admet-3065	1044	2	169	169	NUM
admet-3065	1044	3	]	]	X
admet-3065	1044	4	a.t	a.t	PROPN
admet-3065	1044	5	.	.	PROPN
admet-3065	1044	6	florence	florence	NOUN
admet-3065	1044	7	.	.	PUNCT
admet-3065	1045	1	"	"	PUNCT
admet-3065	1045	2	targeting	target	VERB
admet-3065	1045	3	"	"	PUNCT
admet-3065	1045	4	nanoparticles	nanoparticle	NOUN
admet-3065	1045	5	:	:	PUNCT
admet-3065	1045	6	the	the	DET
admet-3065	1045	7	constraints	constraint	NOUN
admet-3065	1045	8	of	of	ADP
admet-3065	1045	9	physical	physical	ADJ
admet-3065	1045	10	laws	law	NOUN
admet-3065	1045	11	and	and	CCONJ
admet-3065	1045	12	physical	physical	ADJ
admet-3065	1045	13	barriers	barrier	NOUN
admet-3065	1045	14	.	.	PUNCT
admet-3065	1046	1	journal	journal	NOUN
admet-3065	1046	2	of	of	ADP
admet-3065	1046	3	controlled	control	VERB
admet-3065	1046	4	release	release	NOUN
admet-3065	1046	5	164	164	NUM
admet-3065	1046	6	(	(	PUNCT
admet-3065	1046	7	2012	2012	NUM
admet-3065	1046	8	)	)	PUNCT
admet-3065	1046	9	115	115	NUM
admet-3065	1046	10	-	-	SYM
admet-3065	1046	11	124	124	NUM
admet-3065	1046	12	.	.	PUNCT
admet-3065	1047	1	https://doi.org/10.1016/j.jconrel.2012.03.022	https://doi.org/10.1016/j.jconrel.2012.03.022	NOUN
admet-3065	1047	2	[	[	X
admet-3065	1047	3	170	170	NUM
admet-3065	1047	4	]	]	X
admet-3065	1047	5	j.m	j.m	PROPN
admet-3065	1047	6	.	.	PROPN
admet-3065	1047	7	morachis	morachis	PROPN
admet-3065	1047	8	,	,	PUNCT
admet-3065	1047	9	e.a	e.a	PROPN
admet-3065	1047	10	.	.	PROPN
admet-3065	1047	11	mahmoud	mahmoud	PROPN
admet-3065	1047	12	,	,	PUNCT
admet-3065	1047	13	a.	a.	NOUN
admet-3065	1047	14	almutairi	almutairi	NOUN
admet-3065	1047	15	.	.	PUNCT
admet-3065	1048	1	physical	physical	ADJ
admet-3065	1048	2	and	and	CCONJ
admet-3065	1048	3	chemical	chemical	NOUN
admet-3065	1048	4	strategies	strategy	NOUN
admet-3065	1048	5	for	for	ADP
admet-3065	1048	6	therapeutic	therapeutic	ADJ
admet-3065	1048	7	delivery	delivery	NOUN
admet-3065	1048	8	by	by	ADP
admet-3065	1048	9	using	use	VERB
admet-3065	1048	10	polymeric	polymeric	ADJ
admet-3065	1048	11	nanoparticles	nanoparticle	NOUN
admet-3065	1048	12	.	.	PUNCT
admet-3065	1049	1	pharmacological	pharmacological	ADJ
admet-3065	1049	2	reviews	review	NOUN
admet-3065	1049	3	64	64	NUM
admet-3065	1049	4	(	(	PUNCT
admet-3065	1049	5	2012	2012	NUM
admet-3065	1049	6	)	)	PUNCT
admet-3065	1049	7	505	505	NUM
admet-3065	1049	8	-	-	SYM
admet-3065	1049	9	519	519	NUM
admet-3065	1049	10	.	.	PUNCT
admet-3065	1049	11	https://doi.org/10.1124/pr.111.005363	https://doi.org/10.1124/pr.111.005363	VERB
admet-3065	1050	1	[	[	X
admet-3065	1050	2	171	171	NUM
admet-3065	1050	3	]	]	X
admet-3065	1050	4	d.k	d.k	PROPN
admet-3065	1050	5	.	.	PROPN
admet-3065	1050	6	chang	chang	PROPN
admet-3065	1050	7	,	,	PUNCT
admet-3065	1050	8	p.c	p.c	PROPN
admet-3065	1050	9	.	.	PROPN
admet-3065	1050	10	li	li	PROPN
admet-3065	1050	11	,	,	PUNCT
admet-3065	1050	12	r.m	r.m	PROPN
admet-3065	1050	13	.	.	PROPN
admet-3065	1050	14	lu	lu	PROPN
admet-3065	1050	15	,	,	PUNCT
admet-3065	1050	16	w.n	w.n	PROPN
admet-3065	1050	17	.	.	PROPN
admet-3065	1050	18	jane	jane	PROPN
admet-3065	1050	19	,	,	PUNCT
admet-3065	1050	20	h.c	h.c	PROPN
admet-3065	1050	21	.	.	PUNCT
admet-3065	1050	22	wu	wu	PROPN
admet-3065	1050	23	.	.	PUNCT
admet-3065	1051	1	peptide	peptide	NOUN
admet-3065	1051	2	-	-	PUNCT
admet-3065	1051	3	mediated	mediate	VERB
admet-3065	1051	4	liposomal	liposomal	ADJ
admet-3065	1051	5	doxorubicin	doxorubicin	PROPN
admet-3065	1051	6	enhances	enhance	VERB
admet-3065	1051	7	drug	drug	NOUN
admet-3065	1051	8	delivery	delivery	NOUN
admet-3065	1051	9	efficiency	efficiency	NOUN
admet-3065	1051	10	and	and	CCONJ
admet-3065	1051	11	therapeutic	therapeutic	ADJ
admet-3065	1051	12	efficacy	efficacy	NOUN
admet-3065	1051	13	in	in	ADP
admet-3065	1051	14	animal	animal	NOUN
admet-3065	1051	15	models	model	NOUN
admet-3065	1051	16	.	.	PUNCT
admet-3065	1052	1	plos	plos	PROPN
admet-3065	1052	2	one	one	NUM
admet-3065	1052	3	8	8	NUM
admet-3065	1052	4	(	(	PUNCT
admet-3065	1052	5	2013	2013	NUM
admet-3065	1052	6	)	)	PUNCT
admet-3065	1052	7	83239	83239	NUM
admet-3065	1052	8	.	.	PUNCT
admet-3065	1053	1	https://doi.org/10.1371/journal.pone.0083239	https://doi.org/10.1371/journal.pone.0083239	PROPN
admet-3065	1054	1	[	[	X
admet-3065	1054	2	172	172	NUM
admet-3065	1054	3	]	]	PUNCT
admet-3065	1054	4	z.	z.	PROPN
admet-3065	1054	5	jiang	jiang	PROPN
admet-3065	1054	6	,	,	PUNCT
admet-3065	1054	7	j.	j.	PROPN
admet-3065	1054	8	guan	guan	PROPN
admet-3065	1054	9	,	,	PUNCT
admet-3065	1054	10	j.	j.	PROPN
admet-3065	1054	11	qian	qian	PROPN
admet-3065	1054	12	,	,	PUNCT
admet-3065	1054	13	c.	c.	PROPN
admet-3065	1054	14	zhan	zhan	PROPN
admet-3065	1054	15	.	.	PUNCT
admet-3065	1055	1	peptide	peptide	PROPN
admet-3065	1055	2	ligand	ligand	NOUN
admet-3065	1055	3	-	-	PUNCT
admet-3065	1055	4	mediated	mediate	VERB
admet-3065	1055	5	targeted	target	VERB
admet-3065	1055	6	drug	drug	NOUN
admet-3065	1055	7	delivery	delivery	NOUN
admet-3065	1055	8	of	of	ADP
admet-3065	1055	9	nanomedicines	nanomedicine	NOUN
admet-3065	1055	10	.	.	PUNCT
admet-3065	1056	1	biomaterials	biomaterial	NOUN
admet-3065	1056	2	science	science	VERB
admet-3065	1056	3	7	7	NUM
admet-3065	1056	4	(	(	PUNCT
admet-3065	1056	5	2019	2019	NUM
admet-3065	1056	6	)	)	PUNCT
admet-3065	1056	7	461	461	NUM
admet-3065	1056	8	-	-	SYM
admet-3065	1056	9	471	471	NUM
admet-3065	1056	10	.	.	PUNCT
admet-3065	1057	1	https://doi.org/10.1039/c8bm01340c	https://doi.org/10.1039/c8bm01340c	ADJ
admet-3065	1057	2	[	[	X
admet-3065	1057	3	173	173	X
admet-3065	1057	4	]	]	X
admet-3065	1057	5	v.	v.	PROPN
admet-3065	1057	6	artemyev	artemyev	PROPN
admet-3065	1057	7	,	,	PUNCT
admet-3065	1057	8	a.	a.	PROPN
admet-3065	1057	9	gubaeva	gubaeva	PROPN
admet-3065	1057	10	,	,	PUNCT
admet-3065	1057	11	a.i	a.i	PROPN
admet-3065	1057	12	.	.	PROPN
admet-3065	1057	13	paremskaia	paremskaia	PROPN
admet-3065	1057	14	,	,	PUNCT
admet-3065	1057	15	a.a	a.a	PROPN
admet-3065	1057	16	.	.	PROPN
admet-3065	1057	17	dzhioeva	dzhioeva	PROPN
admet-3065	1057	18	,	,	PUNCT
admet-3065	1057	19	a.	a.	PROPN
admet-3065	1057	20	deviatkin	deviatkin	PROPN
admet-3065	1057	21	,	,	PUNCT
admet-3065	1057	22	s.g	s.g	PROPN
admet-3065	1057	23	.	.	PROPN
admet-3065	1057	24	feoktistova	feoktistova	PROPN
admet-3065	1057	25	,	,	PUNCT
admet-3065	1057	26	o.	o.	PROPN
admet-3065	1057	27	mityaeva	mityaeva	PROPN
admet-3065	1057	28	,	,	PUNCT
admet-3065	1057	29	p.y	p.y	PROPN
admet-3065	1057	30	.	.	PROPN
admet-3065	1057	31	volchkov	volchkov	PROPN
admet-3065	1057	32	.	.	PUNCT
admet-3065	1058	1	synthetic	synthetic	ADJ
admet-3065	1058	2	promoters	promoter	NOUN
admet-3065	1058	3	in	in	ADP
admet-3065	1058	4	gene	gene	NOUN
admet-3065	1058	5	therapy	therapy	NOUN
admet-3065	1058	6	:	:	PUNCT
admet-3065	1058	7	design	design	NOUN
admet-3065	1058	8	approaches	approach	NOUN
admet-3065	1058	9	,	,	PUNCT
admet-3065	1058	10	features	feature	NOUN
admet-3065	1058	11	and	and	CCONJ
admet-3065	1058	12	applications	application	NOUN
admet-3065	1058	13	.	.	PUNCT
admet-3065	1059	1	cells	cell	NOUN
admet-3065	1059	2	13	13	NUM
admet-3065	1059	3	(	(	PUNCT
admet-3065	1059	4	2024	2024	NUM
admet-3065	1059	5	)	)	PUNCT
admet-3065	1059	6	1963	1963	NUM
admet-3065	1059	7	.	.	PUNCT
admet-3065	1060	1	https://doi.org/10.3390/cells13231963	https://doi.org/10.3390/cells13231963	PROPN
admet-3065	1061	1	[	[	X
admet-3065	1061	2	174	174	NUM
admet-3065	1061	3	]	]	PUNCT
admet-3065	1061	4	.m	.m	PROPN
admet-3065	1061	5	.	.	PUNCT
admet-3065	1062	1	nettelbeck	nettelbeck	PROPN
admet-3065	1062	2	,	,	PUNCT
admet-3065	1062	3	v.	v.	PROPN
admet-3065	1062	4	jérôme	jérôme	PROPN
admet-3065	1062	5	,	,	PUNCT
admet-3065	1062	6	r.	r.	PROPN
admet-3065	1062	7	müller	müller	PROPN
admet-3065	1062	8	.	.	PUNCT
admet-3065	1063	1	gene	gene	NOUN
admet-3065	1063	2	therapy	therapy	NOUN
admet-3065	1063	3	:	:	PUNCT
admet-3065	1063	4	designer	designer	NOUN
admet-3065	1063	5	promoters	promoter	NOUN
admet-3065	1063	6	for	for	ADP
admet-3065	1063	7	tumour	tumour	NOUN
admet-3065	1063	8	targeting	targeting	NOUN
admet-3065	1063	9	.	.	PUNCT
admet-3065	1064	1	trends	trend	NOUN
admet-3065	1064	2	in	in	ADP
admet-3065	1064	3	genetics	genetic	NOUN
admet-3065	1064	4	16	16	NUM
admet-3065	1064	5	(	(	PUNCT
admet-3065	1064	6	2000	2000	NUM
admet-3065	1064	7	)	)	PUNCT
admet-3065	1064	8	174	174	NUM
admet-3065	1064	9	-	-	SYM
admet-3065	1064	10	181	181	NUM
admet-3065	1064	11	.	.	PUNCT
admet-3065	1065	1	https://doi.org/10.1016/s0168-9525(99)01950-2	https://doi.org/10.1016/s0168-9525(99)01950-2	PROPN
admet-3065	1065	2	.	.	PUNCT
admet-3065	1066	1	[	[	X
admet-3065	1066	2	175	175	NUM
admet-3065	1066	3	]	]	X
admet-3065	1066	4	w.	w.	PROPN
admet-3065	1066	5	alshaer	alshaer	PROPN
admet-3065	1066	6	,	,	PUNCT
admet-3065	1066	7	h.	h.	PROPN
admet-3065	1066	8	hillaireau	hillaireau	PROPN
admet-3065	1066	9	,	,	PUNCT
admet-3065	1066	10	j.	j.	PROPN
admet-3065	1066	11	vergnaud	vergnaud	PROPN
admet-3065	1066	12	,	,	PUNCT
admet-3065	1066	13	s.	s.	PROPN
admet-3065	1066	14	ismail	ismail	PROPN
admet-3065	1066	15	,	,	PUNCT
admet-3065	1066	16	e.	e.	PROPN
admet-3065	1066	17	fattal	fattal	PROPN
admet-3065	1066	18	.	.	PUNCT
admet-3065	1067	1	functionalizing	functionalize	VERB
admet-3065	1067	2	liposomes	liposome	NOUN
admet-3065	1067	3	with	with	ADP
admet-3065	1067	4	anti	anti	ADJ
admet-3065	1067	5	-	-	ADJ
admet-3065	1067	6	cd44	cd44	ADJ
admet-3065	1067	7	aptamer	aptamer	NOUN
admet-3065	1067	8	for	for	ADP
admet-3065	1067	9	selective	selective	ADJ
admet-3065	1067	10	targeting	targeting	NOUN
admet-3065	1067	11	of	of	ADP
admet-3065	1067	12	cancer	cancer	NOUN
admet-3065	1067	13	cells	cell	NOUN
admet-3065	1067	14	.	.	PUNCT
admet-3065	1068	1	bioconjugate	bioconjugate	NOUN
admet-3065	1068	2	chemistry	chemistry	NOUN
admet-3065	1068	3	26	26	NUM
admet-3065	1068	4	(	(	PUNCT
admet-3065	1068	5	2015	2015	NUM
admet-3065	1068	6	)	)	PUNCT
admet-3065	1068	7	1307	1307	NUM
admet-3065	1068	8	-	-	SYM
admet-3065	1068	9	1313	1313	NUM
admet-3065	1068	10	.	.	PUNCT
admet-3065	1069	1	https://doi.org/10.1021/bc5004313	https://doi.org/10.1021/bc5004313	PRON
admet-3065	1070	1	[	[	X
admet-3065	1070	2	176	176	X
admet-3065	1070	3	]	]	PUNCT
admet-3065	1070	4	j.	j.	PROPN
admet-3065	1070	5	gubernator	gubernator	PROPN
admet-3065	1070	6	.	.	PUNCT
admet-3065	1071	1	active	active	ADJ
admet-3065	1071	2	methods	method	NOUN
admet-3065	1071	3	of	of	ADP
admet-3065	1071	4	drug	drug	NOUN
admet-3065	1071	5	loading	loading	NOUN
admet-3065	1071	6	into	into	ADP
admet-3065	1071	7	liposomes	liposome	NOUN
admet-3065	1071	8	:	:	PUNCT
admet-3065	1071	9	recent	recent	ADJ
admet-3065	1071	10	strategies	strategy	NOUN
admet-3065	1071	11	for	for	ADP
admet-3065	1071	12	stable	stable	ADJ
admet-3065	1071	13	drug	drug	NOUN
admet-3065	1071	14	entrapment	entrapment	NOUN
admet-3065	1071	15	and	and	CCONJ
admet-3065	1071	16	increased	increase	VERB
admet-3065	1071	17	in	in	ADP
admet-3065	1071	18	vivo	vivo	NOUN
admet-3065	1071	19	activity	activity	NOUN
admet-3065	1071	20	.	.	PUNCT
admet-3065	1072	1	expert	expert	ADJ
admet-3065	1072	2	opinion	opinion	NOUN
admet-3065	1072	3	on	on	ADP
admet-3065	1072	4	drug	drug	NOUN
admet-3065	1072	5	delivery	delivery	NOUN
admet-3065	1072	6	8	8	NUM
admet-3065	1072	7	(	(	PUNCT
admet-3065	1072	8	2011	2011	NUM
admet-3065	1072	9	)	)	PUNCT
admet-3065	1072	10	565	565	NUM
admet-3065	1072	11	-	-	SYM
admet-3065	1072	12	580	580	NUM
admet-3065	1072	13	.	.	PUNCT
admet-3065	1072	14	https://doi.org/10.1517/17425247.2011.566552	https://doi.org/10.1517/17425247.2011.566552	PUNCT
admet-3065	1073	1	[	[	X
admet-3065	1073	2	177	177	NUM
admet-3065	1073	3	]	]	X
admet-3065	1073	4	l.d	l.d	PROPN
admet-3065	1073	5	.	.	PROPN
admet-3065	1073	6	leserman	leserman	PROPN
admet-3065	1073	7	,	,	PUNCT
admet-3065	1073	8	j.n	j.n	PROPN
admet-3065	1073	9	.	.	PROPN
admet-3065	1073	10	weinstein	weinstein	PROPN
admet-3065	1073	11	,	,	PUNCT
admet-3065	1073	12	r.	r.	PROPN
admet-3065	1073	13	blumenthal	blumenthal	PROPN
admet-3065	1073	14	,	,	PUNCT
admet-3065	1073	15	w.d	w.d	PROPN
admet-3065	1073	16	.	.	PROPN
admet-3065	1073	17	terry	terry	PROPN
admet-3065	1073	18	.	.	PUNCT
admet-3065	1074	1	receptor	receptor	NOUN
admet-3065	1074	2	-	-	PUNCT
admet-3065	1074	3	mediated	mediate	VERB
admet-3065	1074	4	endocytosis	endocytosis	NOUN
admet-3065	1074	5	of	of	ADP
admet-3065	1074	6	antibody	antibody	NOUN
admet-3065	1074	7	-	-	PUNCT
admet-3065	1074	8	opsonized	opsonize	VERB
admet-3065	1074	9	liposomes	liposome	NOUN
admet-3065	1074	10	by	by	ADP
admet-3065	1074	11	tumor	tumor	NOUN
admet-3065	1074	12	cells	cell	NOUN
admet-3065	1074	13	.	.	PUNCT
admet-3065	1075	1	proceedings	proceeding	NOUN
admet-3065	1075	2	of	of	ADP
admet-3065	1075	3	the	the	DET
admet-3065	1075	4	national	national	PROPN
admet-3065	1075	5	academy	academy	PROPN
admet-3065	1075	6	of	of	ADP
admet-3065	1075	7	sciences	sciences	PROPN
admet-3065	1075	8	77	77	NUM
admet-3065	1075	9	(	(	PUNCT
admet-3065	1075	10	1980	1980	NUM
admet-3065	1075	11	)	)	PUNCT
admet-3065	1075	12	4089	4089	NUM
admet-3065	1075	13	-	-	SYM
admet-3065	1075	14	4093	4093	NUM
admet-3065	1075	15	.	.	PUNCT
admet-3065	1076	1	https://doi.org/10.1073/pnas.77.7.4089	https://doi.org/10.1073/pnas.77.7.4089	NOUN
admet-3065	1077	1	[	[	X
admet-3065	1077	2	178	178	NUM
admet-3065	1077	3	]	]	X
admet-3065	1077	4	n.	n.	PROPN
admet-3065	1077	5	d'avanzo	d'avanzo	PROPN
admet-3065	1077	6	,	,	PUNCT
admet-3065	1077	7	g.	g.	PROPN
admet-3065	1077	8	torrieri	torrieri	PROPN
admet-3065	1077	9	,	,	PUNCT
admet-3065	1077	10	p.	p.	PROPN
admet-3065	1077	11	figueiredo	figueiredo	PROPN
admet-3065	1077	12	,	,	PUNCT
admet-3065	1077	13	c.	c.	PROPN
admet-3065	1077	14	celia	celia	PROPN
admet-3065	1077	15	,	,	PUNCT
admet-3065	1077	16	d.	d.	PROPN
admet-3065	1077	17	paolino	paolino	PROPN
admet-3065	1077	18	,	,	PUNCT
admet-3065	1077	19	a.	a.	PROPN
admet-3065	1077	20	correia	correia	PROPN
admet-3065	1077	21	,	,	PUNCT
admet-3065	1077	22	k.	k.	PROPN
admet-3065	1077	23	moslova	moslova	PROPN
admet-3065	1077	24	,	,	PUNCT
admet-3065	1077	25	t.	t.	NOUN
admet-3065	1077	26	teesalu	teesalu	NOUN
admet-3065	1077	27	,	,	PUNCT
admet-3065	1077	28	m.	m.	NOUN
admet-3065	1077	29	fresta	fresta	PROPN
admet-3065	1077	30	,	,	PUNCT
admet-3065	1077	31	h.a	h.a	PROPN
admet-3065	1077	32	.	.	PROPN
admet-3065	1077	33	santos	santos	PROPN
admet-3065	1077	34	.	.	PUNCT
admet-3065	1078	1	lintt1	lintt1	NOUN
admet-3065	1078	2	peptide	peptide	NOUN
admet-3065	1078	3	-	-	PUNCT
admet-3065	1078	4	functionalized	functionalize	VERB
admet-3065	1078	5	liposomes	liposome	NOUN
admet-3065	1078	6	for	for	ADP
admet-3065	1078	7	targeted	target	VERB
admet-3065	1078	8	breast	breast	NOUN
admet-3065	1078	9	cancer	cancer	NOUN
admet-3065	1078	10	therapy	therapy	NOUN
admet-3065	1078	11	.	.	PUNCT
admet-3065	1079	1	international	international	ADJ
admet-3065	1079	2	journal	journal	PROPN
admet-3065	1079	3	of	of	ADP
admet-3065	1079	4	pharmaceutics	pharmaceutic	NOUN
admet-3065	1079	5	597	597	NUM
admet-3065	1079	6	(	(	PUNCT
admet-3065	1079	7	2021	2021	NUM
admet-3065	1079	8	)	)	PUNCT
admet-3065	1079	9	120346	120346	NUM
admet-3065	1079	10	-	-	SYM
admet-3065	1079	11	120346	120346	NUM
admet-3065	1079	12	.	.	PUNCT
admet-3065	1080	1	https://doi.org/10.1016/j.ijpharm.2021.120346	https://doi.org/10.1016/j.ijpharm.2021.120346	VERB
admet-3065	1080	2	[	[	X
admet-3065	1080	3	179	179	NUM
admet-3065	1080	4	]	]	X
admet-3065	1080	5	e.	e.	PROPN
admet-3065	1080	6	koren	koren	PROPN
admet-3065	1080	7	,	,	PUNCT
admet-3065	1080	8	a.	a.	PROPN
admet-3065	1080	9	apte	apte	PROPN
admet-3065	1080	10	,	,	PUNCT
admet-3065	1080	11	a.	a.	PROPN
admet-3065	1080	12	jani	jani	PROPN
admet-3065	1080	13	,	,	PUNCT
admet-3065	1080	14	v.p	v.p	PROPN
admet-3065	1080	15	.	.	PROPN
admet-3065	1080	16	torchilin	torchilin	PROPN
admet-3065	1080	17	.	.	PUNCT
admet-3065	1081	1	multifunctional	multifunctional	PROPN
admet-3065	1081	2	pegylated	pegylate	VERB
admet-3065	1081	3	2c5	2c5	PROPN
admet-3065	1081	4	-	-	PUNCT
admet-3065	1081	5	immunoliposomes	immunoliposome	NOUN
admet-3065	1081	6	containing	contain	VERB
admet-3065	1081	7	ph	ph	ADJ
admet-3065	1081	8	-	-	ADJ
admet-3065	1081	9	sensitive	sensitive	ADJ
admet-3065	1081	10	bonds	bond	NOUN
admet-3065	1081	11	and	and	CCONJ
admet-3065	1081	12	tat	tat	NOUN
admet-3065	1081	13	peptide	peptide	NOUN
admet-3065	1081	14	for	for	ADP
admet-3065	1081	15	enhanced	enhanced	ADJ
admet-3065	1081	16	tumor	tumor	NOUN
admet-3065	1081	17	cell	cell	NOUN
admet-3065	1081	18	internalization	internalization	NOUN
admet-3065	1081	19	and	and	CCONJ
admet-3065	1081	20	cytotoxicity	cytotoxicity	NOUN
admet-3065	1081	21	.	.	PUNCT
admet-3065	1082	1	journal	journal	NOUN
admet-3065	1082	2	of	of	ADP
admet-3065	1082	3	controlled	control	VERB
admet-3065	1082	4	release	release	NOUN
admet-3065	1082	5	160	160	NUM
admet-3065	1082	6	(	(	PUNCT
admet-3065	1082	7	2012	2012	NUM
admet-3065	1082	8	)	)	PUNCT
admet-3065	1082	9	264	264	NUM
admet-3065	1082	10	-	-	SYM
admet-3065	1082	11	273	273	NUM
admet-3065	1082	12	.	.	PUNCT
admet-3065	1083	1	https://doi.org/10.1016/j.jconrel.2011.12.002	https://doi.org/10.1016/j.jconrel.2011.12.002	NOUN
admet-3065	1083	2	[	[	NOUN
admet-3065	1083	3	180	180	NUM
admet-3065	1083	4	]	]	X
admet-3065	1083	5	d.	d.	PROPN
admet-3065	1083	6	paolino	paolino	PROPN
admet-3065	1083	7	,	,	PUNCT
admet-3065	1083	8	d.	d.	PROPN
admet-3065	1083	9	cosco	cosco	PROPN
admet-3065	1083	10	,	,	PUNCT
admet-3065	1083	11	m.	m.	NOUN
admet-3065	1083	12	gaspari	gaspari	PROPN
admet-3065	1083	13	,	,	PUNCT
admet-3065	1083	14	m.	m.	NOUN
admet-3065	1083	15	celano	celano	PROPN
admet-3065	1083	16	,	,	PUNCT
admet-3065	1083	17	j.	j.	PROPN
admet-3065	1083	18	wolfram	wolfram	PROPN
admet-3065	1083	19	,	,	PUNCT
admet-3065	1083	20	p.	p.	PROPN
admet-3065	1083	21	voce	voce	PROPN
admet-3065	1083	22	,	,	PUNCT
admet-3065	1083	23	e.	e.	PROPN
admet-3065	1083	24	puxeddu	puxeddu	PROPN
admet-3065	1083	25	,	,	PUNCT
admet-3065	1083	26	s.	s.	PROPN
admet-3065	1083	27	filetti	filetti	PROPN
admet-3065	1083	28	,	,	PUNCT
admet-3065	1083	29	c.	c.	PROPN
admet-3065	1083	30	celia	celia	PROPN
admet-3065	1083	31	,	,	PUNCT
admet-3065	1083	32	m.	m.	NOUN
admet-3065	1083	33	ferrari	ferrari	PROPN
admet-3065	1083	34	,	,	PUNCT
admet-3065	1083	35	d.	d.	PROPN
admet-3065	1083	36	russo	russo	PROPN
admet-3065	1083	37	,	,	PUNCT
admet-3065	1083	38	m.	m.	NOUN
admet-3065	1083	39	fresta	fresta	PROPN
admet-3065	1083	40	.	.	PUNCT
admet-3065	1084	1	targeting	target	VERB
admet-3065	1084	2	the	the	DET
admet-3065	1084	3	thyroid	thyroid	NOUN
admet-3065	1084	4	gland	gland	NOUN
admet-3065	1084	5	with	with	ADP
admet-3065	1084	6	thyroid	thyroid	NOUN
admet-3065	1084	7	-	-	PUNCT
admet-3065	1084	8	stimulating	stimulate	VERB
admet-3065	1084	9	hormone	hormone	NOUN
admet-3065	1084	10	(	(	PUNCT
admet-3065	1084	11	tsh)-nanoliposomes	tsh)-nanoliposome	NOUN
admet-3065	1084	12	.	.	PROPN
admet-3065	1085	1	biomaterials	biomaterial	NOUN
admet-3065	1085	2	35	35	NUM
admet-3065	1085	3	(	(	PUNCT
admet-3065	1085	4	2014	2014	NUM
admet-3065	1085	5	)	)	PUNCT
admet-3065	1085	6	7101	7101	NUM
admet-3065	1085	7	-	-	SYM
admet-3065	1085	8	7109	7109	NUM
admet-3065	1085	9	.	.	PUNCT
admet-3065	1086	1	https://doi.org/10.1016/j.biomaterials.2014.04.088	https://doi.org/10.1016/j.biomaterials.2014.04.088	PRON
admet-3065	1086	2	https://doi.org/10.1016/0014-5793(90)81016-h	https://doi.org/10.1016/0014-5793(90)81016-h	ADJ
admet-3065	1086	3	https://doi.org/10.1016/j.colsurfa.2015.03.006	https://doi.org/10.1016/j.colsurfa.2015.03.006	NOUN
admet-3065	1086	4	https://doi.org/10.1042/bst0350068	https://doi.org/10.1042/bst0350068	NUM
admet-3065	1086	5	https://doi.org/10.1113/expphysiol.2004.028126	https://doi.org/10.1113/expphysiol.2004.028126	PROPN
admet-3065	1086	6	https://doi.org/10.1186/s40779-023-00445-z	https://doi.org/10.1186/s40779-023-00445-z	PROPN
admet-3065	1086	7	https://doi.org/10.1016/j.jconrel.2012.03.022	https://doi.org/10.1016/j.jconrel.2012.03.022	NOUN
admet-3065	1086	8	https://doi.org/10.1124/pr.111.005363	https://doi.org/10.1124/pr.111.005363	VERB
admet-3065	1086	9	https://doi.org/10.1371/journal.pone.0083239	https://doi.org/10.1371/journal.pone.0083239	NOUN
admet-3065	1086	10	https://doi.org/10.1039/c8bm01340c	https://doi.org/10.1039/c8bm01340c	PROPN
admet-3065	1086	11	https://doi.org/10.3390/cells13231963	https://doi.org/10.3390/cells13231963	VERB
admet-3065	1086	12	https://doi.org/10.1016/s0168-9525(99)01950-2	https://doi.org/10.1016/s0168-9525(99)01950-2	PROPN
admet-3065	1086	13	https://doi.org/10.1021/bc5004313	https://doi.org/10.1021/bc5004313	ADP
admet-3065	1086	14	https://doi.org/10.1517/17425247.2011.566552	https://doi.org/10.1517/17425247.2011.566552	NOUN
admet-3065	1086	15	https://doi.org/10.1073/pnas.77.7.4089	https://doi.org/10.1073/pnas.77.7.4089	NOUN
admet-3065	1086	16	https://doi.org/10.1016/j.ijpharm.2021.120346	https://doi.org/10.1016/j.ijpharm.2021.120346	ADJ
admet-3065	1086	17	https://doi.org/10.1016/j.jconrel.2011.12.002	https://doi.org/10.1016/j.jconrel.2011.12.002	NOUN
admet-3065	1086	18	https://doi.org/10.1016/j.biomaterials.2014.04.088	https://doi.org/10.1016/j.biomaterials.2014.04.088	PRON
admet-3065	1086	19	admet	admet	X
admet-3065	1086	20	&	&	CCONJ
admet-3065	1086	21	dmpk	dmpk	PROPN
admet-3065	1086	22	00(0	00(0	PROPN
admet-3065	1086	23	)	)	PUNCT
admet-3065	1086	24	(	(	PUNCT
admet-3065	1086	25	2025	2025	NUM
admet-3065	1086	26	)	)	PUNCT
admet-3065	1086	27	3065	3065	NUM
admet-3065	1086	28	liposome	liposome	NOUN
admet-3065	1086	29	-	-	PUNCT
admet-3065	1086	30	mediated	mediate	VERB
admet-3065	1086	31	gene	gene	NOUN
admet-3065	1086	32	delivery	delivery	NOUN
admet-3065	1086	33	doi	doi	NOUN
admet-3065	1086	34	:	:	PUNCT
admet-3065	1086	35	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	1086	36	29	29	NUM
admet-3065	1087	1	[	[	X
admet-3065	1087	2	181	181	NUM
admet-3065	1087	3	]	]	X
admet-3065	1087	4	h.	h.	PROPN
admet-3065	1087	5	nsairat	nsairat	PROPN
admet-3065	1087	6	,	,	PUNCT
admet-3065	1087	7	d.	d.	PROPN
admet-3065	1087	8	khater	khater	PROPN
admet-3065	1087	9	,	,	PUNCT
admet-3065	1087	10	u.	u.	PROPN
admet-3065	1087	11	sayed	sayed	PROPN
admet-3065	1087	12	,	,	PUNCT
admet-3065	1087	13	f.	f.	PROPN
admet-3065	1087	14	odeh	odeh	PROPN
admet-3065	1087	15	,	,	PUNCT
admet-3065	1087	16	a.	a.	PROPN
admet-3065	1087	17	al	al	PROPN
admet-3065	1087	18	bawab	bawab	PROPN
admet-3065	1087	19	,	,	PUNCT
admet-3065	1087	20	w.	w.	PROPN
admet-3065	1087	21	alshaer	alshaer	PROPN
admet-3065	1087	22	.	.	PUNCT
admet-3065	1088	1	liposomes	liposome	NOUN
admet-3065	1088	2	:	:	PUNCT
admet-3065	1088	3	structure	structure	NOUN
admet-3065	1088	4	,	,	PUNCT
admet-3065	1088	5	composition	composition	NOUN
admet-3065	1088	6	,	,	PUNCT
admet-3065	1088	7	types	type	NOUN
admet-3065	1088	8	,	,	PUNCT
admet-3065	1088	9	and	and	CCONJ
admet-3065	1088	10	clinical	clinical	ADJ
admet-3065	1088	11	applications	application	NOUN
admet-3065	1088	12	.	.	PUNCT
admet-3065	1089	1	heliyon	heliyon	NOUN
admet-3065	1089	2	8	8	NUM
admet-3065	1089	3	(	(	PUNCT
admet-3065	1089	4	2022	2022	NUM
admet-3065	1089	5	)	)	PUNCT
admet-3065	1089	6	09394	09394	NUM
admet-3065	1089	7	.	.	PUNCT
admet-3065	1090	1	https://doi.org/10.1016/j.heliyon.2022.e09394	https://doi.org/10.1016/j.heliyon.2022.e09394	X
admet-3065	1091	1	[	[	X
admet-3065	1091	2	182	182	NUM
admet-3065	1091	3	]	]	PUNCT
admet-3065	1091	4	k.	k.	PROPN
admet-3065	1091	5	kappler	kappler	PROPN
admet-3065	1091	6	,	,	PUNCT
admet-3065	1091	7	t.	t.	PROPN
admet-3065	1091	8	hennet	hennet	PROPN
admet-3065	1091	9	.	.	PUNCT
admet-3065	1092	1	emergence	emergence	NOUN
admet-3065	1092	2	and	and	CCONJ
admet-3065	1092	3	significance	significance	NOUN
admet-3065	1092	4	of	of	ADP
admet-3065	1092	5	carbohydrate	carbohydrate	NOUN
admet-3065	1092	6	-	-	PUNCT
admet-3065	1092	7	specific	specific	ADJ
admet-3065	1092	8	antibodies	antibody	NOUN
admet-3065	1092	9	.	.	PUNCT
admet-3065	1093	1	genes	gene	NOUN
admet-3065	1093	2	and	and	CCONJ
admet-3065	1093	3	immunity	immunity	NOUN
admet-3065	1093	4	21	21	NUM
admet-3065	1093	5	(	(	PUNCT
admet-3065	1093	6	2020	2020	NUM
admet-3065	1093	7	)	)	PUNCT
admet-3065	1093	8	224	224	NUM
admet-3065	1093	9	-	-	SYM
admet-3065	1093	10	239	239	NUM
admet-3065	1093	11	.	.	PUNCT
admet-3065	1094	1	https://doi.org/10.1038/s41435-020-0105-9	https://doi.org/10.1038/s41435-020-0105-9	NUM
admet-3065	1094	2	[	[	X
admet-3065	1094	3	183	183	NUM
admet-3065	1094	4	]	]	PUNCT
admet-3065	1094	5	i.	i.	PROPN
admet-3065	1094	6	sela	sela	PROPN
admet-3065	1094	7	-	-	PUNCT
admet-3065	1094	8	culang	culang	PROPN
admet-3065	1094	9	,	,	PUNCT
admet-3065	1094	10	v.	v.	PROPN
admet-3065	1094	11	kunik	kunik	PROPN
admet-3065	1094	12	,	,	PUNCT
admet-3065	1094	13	y.	y.	PROPN
admet-3065	1094	14	ofran	ofran	PROPN
admet-3065	1094	15	.	.	PUNCT
admet-3065	1095	1	the	the	DET
admet-3065	1095	2	structural	structural	ADJ
admet-3065	1095	3	basis	basis	NOUN
admet-3065	1095	4	of	of	ADP
admet-3065	1095	5	antibody	antibody	NOUN
admet-3065	1095	6	-	-	PUNCT
admet-3065	1095	7	antigen	antigen	NOUN
admet-3065	1095	8	recognition	recognition	NOUN
admet-3065	1095	9	.	.	PUNCT
admet-3065	1096	1	frontiers	frontier	NOUN
admet-3065	1096	2	in	in	ADP
admet-3065	1096	3	immunology	immunology	NOUN
admet-3065	1096	4	4	4	NUM
admet-3065	1096	5	(	(	PUNCT
admet-3065	1096	6	2013	2013	NUM
admet-3065	1096	7	)	)	PUNCT
admet-3065	1096	8	302	302	NUM
admet-3065	1096	9	.	.	PUNCT
admet-3065	1096	10	https://doi.org/10.3389/fimmu.2013.00302	https://doi.org/10.3389/fimmu.2013.00302	PROPN
admet-3065	1097	1	[	[	X
admet-3065	1097	2	184	184	NUM
admet-3065	1097	3	]	]	X
admet-3065	1097	4	u.j	u.j	PROPN
admet-3065	1097	5	.	.	PROPN
admet-3065	1097	6	björgvinsdóttir	björgvinsdóttir	PROPN
admet-3065	1097	7	,	,	PUNCT
admet-3065	1097	8	j.b	j.b	PROPN
admet-3065	1097	9	.	.	PROPN
admet-3065	1097	10	larsen	larsen	PROPN
admet-3065	1097	11	,	,	PUNCT
admet-3065	1097	12	m.	m.	NOUN
admet-3065	1097	13	bak	bak	PROPN
admet-3065	1097	14	,	,	PUNCT
admet-3065	1097	15	t.l	t.l	PROPN
admet-3065	1097	16	.	.	PROPN
admet-3065	1097	17	andresen	andresen	PROPN
admet-3065	1097	18	,	,	PUNCT
admet-3065	1097	19	r.	r.	PROPN
admet-3065	1097	20	münter	münter	PROPN
admet-3065	1097	21	.	.	PUNCT
admet-3065	1098	1	targeting	target	VERB
admet-3065	1098	2	antibodies	antibody	NOUN
admet-3065	1098	3	dissociate	dissociate	VERB
admet-3065	1098	4	from	from	ADP
admet-3065	1098	5	drug	drug	NOUN
admet-3065	1098	6	delivery	delivery	NOUN
admet-3065	1098	7	liposomes	liposome	NOUN
admet-3065	1098	8	during	during	ADP
admet-3065	1098	9	blood	blood	NOUN
admet-3065	1098	10	circulation	circulation	NOUN
admet-3065	1098	11	.	.	PUNCT
admet-3065	1099	1	journal	journal	NOUN
admet-3065	1099	2	of	of	ADP
admet-3065	1099	3	controlled	control	VERB
admet-3065	1099	4	release	release	NOUN
admet-3065	1099	5	379	379	NUM
admet-3065	1099	6	(	(	PUNCT
admet-3065	1099	7	2025	2025	NUM
admet-3065	1099	8	)	)	PUNCT
admet-3065	1099	9	982	982	NUM
admet-3065	1099	10	-	-	SYM
admet-3065	1099	11	992	992	NUM
admet-3065	1099	12	.	.	PUNCT
admet-3065	1100	1	https://doi.org/10.1016/j.jconrel.2025.01.047	https://doi.org/10.1016/j.jconrel.2025.01.047	PRON
admet-3065	1100	2	[	[	X
admet-3065	1100	3	185	185	NUM
admet-3065	1100	4	]	]	PUNCT
admet-3065	1100	5	h.	h.	PROPN
admet-3065	1100	6	koo	koo	PROPN
admet-3065	1100	7	,	,	PUNCT
admet-3065	1100	8	m.s	m.s	PROPN
admet-3065	1100	9	.	.	PROPN
admet-3065	1101	1	huh	huh	PROPN
admet-3065	1101	2	,	,	PUNCT
admet-3065	1101	3	i.c	i.c	PROPN
admet-3065	1101	4	.	.	PROPN
admet-3065	1101	5	sun	sun	PROPN
admet-3065	1101	6	,	,	PUNCT
admet-3065	1101	7	s.h	s.h	PROPN
admet-3065	1101	8	.	.	PROPN
admet-3065	1101	9	yuk	yuk	PROPN
admet-3065	1101	10	,	,	PUNCT
admet-3065	1101	11	k.	k.	PROPN
admet-3065	1101	12	choi	choi	PROPN
admet-3065	1101	13	,	,	PUNCT
admet-3065	1101	14	k.	k.	PROPN
admet-3065	1101	15	kim	kim	PROPN
admet-3065	1101	16	,	,	PUNCT
admet-3065	1101	17	i.c	i.c	PROPN
admet-3065	1101	18	.	.	PROPN
admet-3065	1101	19	kwon	kwon	PROPN
admet-3065	1101	20	.	.	PUNCT
admet-3065	1102	1	in	in	ADP
admet-3065	1102	2	vivo	vivo	ADJ
admet-3065	1102	3	targeted	target	VERB
admet-3065	1102	4	delivery	delivery	NOUN
admet-3065	1102	5	of	of	ADP
admet-3065	1102	6	nanoparticles	nanoparticle	NOUN
admet-3065	1102	7	for	for	ADP
admet-3065	1102	8	theranosis	theranosis	NOUN
admet-3065	1102	9	.	.	PUNCT
admet-3065	1103	1	accounts	account	NOUN
admet-3065	1103	2	of	of	ADP
admet-3065	1103	3	chemical	chemical	ADJ
admet-3065	1103	4	research	research	NOUN
admet-3065	1103	5	44	44	NUM
admet-3065	1103	6	(	(	PUNCT
admet-3065	1103	7	2011	2011	NUM
admet-3065	1103	8	)	)	PUNCT
admet-3065	1103	9	1018	1018	NUM
admet-3065	1103	10	-	-	SYM
admet-3065	1103	11	1028	1028	NUM
admet-3065	1103	12	.	.	PUNCT
admet-3065	1104	1	https://doi.org/10.1021/ar2000138	https://doi.org/10.1021/ar2000138	X
admet-3065	1105	1	[	[	X
admet-3065	1105	2	186	186	NUM
admet-3065	1105	3	]	]	X
admet-3065	1105	4	m.t	m.t	PROPN
admet-3065	1105	5	.	.	PROPN
admet-3065	1105	6	manzari	manzari	PROPN
admet-3065	1105	7	,	,	PUNCT
admet-3065	1105	8	y.	y.	PROPN
admet-3065	1105	9	shamay	shamay	PROPN
admet-3065	1105	10	,	,	PUNCT
admet-3065	1105	11	h.	h.	PROPN
admet-3065	1105	12	kiguchi	kiguchi	PROPN
admet-3065	1105	13	,	,	PUNCT
admet-3065	1105	14	n.	n.	PROPN
admet-3065	1105	15	rosen	rosen	PROPN
admet-3065	1105	16	,	,	PUNCT
admet-3065	1105	17	m.	m.	NOUN
admet-3065	1105	18	scaltriti	scaltriti	PROPN
admet-3065	1105	19	,	,	PUNCT
admet-3065	1105	20	d.a	d.a	PROPN
admet-3065	1105	21	.	.	PROPN
admet-3065	1105	22	heller	heller	PROPN
admet-3065	1105	23	.	.	PUNCT
admet-3065	1106	1	targeted	target	VERB
admet-3065	1106	2	drug	drug	NOUN
admet-3065	1106	3	delivery	delivery	NOUN
admet-3065	1106	4	strategies	strategy	NOUN
admet-3065	1106	5	for	for	ADP
admet-3065	1106	6	precision	precision	NOUN
admet-3065	1106	7	medicines	medicine	NOUN
admet-3065	1106	8	.	.	PUNCT
admet-3065	1107	1	nature	nature	NOUN
admet-3065	1107	2	reviews	review	VERB
admet-3065	1107	3	materials	material	NOUN
admet-3065	1107	4	6	6	NUM
admet-3065	1107	5	(	(	PUNCT
admet-3065	1107	6	2021	2021	NUM
admet-3065	1107	7	)	)	PUNCT
admet-3065	1107	8	351	351	NUM
admet-3065	1107	9	-	-	SYM
admet-3065	1107	10	370	370	NUM
admet-3065	1107	11	.	.	PUNCT
admet-3065	1108	1	https://doi.org/10.1038/s41578020-00269-6	https://doi.org/10.1038/s41578020-00269-6	VERB
admet-3065	1108	2	[	[	X
admet-3065	1108	3	187	187	NUM
admet-3065	1108	4	]	]	X
admet-3065	1108	5	f.j	f.j	PROPN
admet-3065	1108	6	.	.	PROPN
admet-3065	1108	7	martin	martin	PROPN
admet-3065	1108	8	,	,	PUNCT
admet-3065	1108	9	d.	d.	PROPN
admet-3065	1108	10	papahadjopoulos	papahadjopoulos	PROPN
admet-3065	1108	11	,	,	PUNCT
admet-3065	1108	12	w.l	w.l	PROPN
admet-3065	1108	13	.	.	PROPN
admet-3065	1108	14	hubbell	hubbell	PROPN
admet-3065	1108	15	.	.	PUNCT
admet-3065	1109	1	immunospecific	immunospecific	PROPN
admet-3065	1109	2	targeting	targeting	NOUN
admet-3065	1109	3	of	of	ADP
admet-3065	1109	4	liposomes	liposome	NOUN
admet-3065	1109	5	to	to	ADP
admet-3065	1109	6	cells	cell	NOUN
admet-3065	1109	7	:	:	PUNCT
admet-3065	1109	8	a	a	DET
admet-3065	1109	9	novel	novel	ADJ
admet-3065	1109	10	and	and	CCONJ
admet-3065	1109	11	efficient	efficient	ADJ
admet-3065	1109	12	method	method	NOUN
admet-3065	1109	13	for	for	ADP
admet-3065	1109	14	covalent	covalent	ADJ
admet-3065	1109	15	attachment	attachment	NOUN
admet-3065	1109	16	of	of	ADP
admet-3065	1109	17	fab	fab	NOUN
admet-3065	1109	18	'	'	PUNCT
admet-3065	1109	19	fragments	fragment	NOUN
admet-3065	1109	20	via	via	ADP
admet-3065	1109	21	disulfide	disulfide	NOUN
admet-3065	1109	22	bonds	bond	NOUN
admet-3065	1109	23	.	.	PUNCT
admet-3065	1110	1	biochemistry	biochemistry	NOUN
admet-3065	1110	2	20	20	NUM
admet-3065	1110	3	(	(	PUNCT
admet-3065	1110	4	1981	1981	NUM
admet-3065	1110	5	)	)	PUNCT
admet-3065	1110	6	4229	4229	NUM
admet-3065	1110	7	-	-	SYM
admet-3065	1110	8	4238	4238	NUM
admet-3065	1110	9	.	.	PUNCT
admet-3065	1111	1	https://doi.org/10.1021/bi00517a043	https://doi.org/10.1021/bi00517a043	PROPN
admet-3065	1111	2	[	[	X
admet-3065	1111	3	188	188	NUM
admet-3065	1111	4	]	]	PUNCT
admet-3065	1111	5	a.	a.	NOUN
admet-3065	1111	6	ohradanova	ohradanova	NOUN
admet-3065	1111	7	-	-	PUNCT
admet-3065	1111	8	repic	repic	ADJ
admet-3065	1111	9	,	,	PUNCT
admet-3065	1111	10	e.	e.	PROPN
admet-3065	1111	11	nogueira	nogueira	PROPN
admet-3065	1111	12	,	,	PUNCT
admet-3065	1111	13	i.	i.	PROPN
admet-3065	1111	14	hartl	hartl	PROPN
admet-3065	1111	15	,	,	PUNCT
admet-3065	1111	16	a.c	a.c	PROPN
admet-3065	1111	17	.	.	PROPN
admet-3065	1111	18	gomes	gome	NOUN
admet-3065	1111	19	,	,	PUNCT
admet-3065	1111	20	a.	a.	PROPN
admet-3065	1111	21	preto	preto	PROPN
admet-3065	1111	22	,	,	PUNCT
admet-3065	1111	23	e.	e.	PROPN
admet-3065	1111	24	steinhuber	steinhuber	PROPN
admet-3065	1111	25	,	,	PUNCT
admet-3065	1111	26	v.	v.	ADP
admet-3065	1111	27	mühlgrabner	mühlgrabner	NOUN
admet-3065	1111	28	,	,	PUNCT
admet-3065	1111	29	m.	m.	NOUN
admet-3065	1111	30	repic	repic	NOUN
admet-3065	1111	31	,	,	PUNCT
admet-3065	1111	32	m.	m.	NOUN
admet-3065	1111	33	kuttke	kuttke	NOUN
admet-3065	1111	34	,	,	PUNCT
admet-3065	1111	35	a.	a.	PROPN
admet-3065	1111	36	zwirzitz	zwirzitz	PROPN
admet-3065	1111	37	,	,	PUNCT
admet-3065	1111	38	m.	m.	PROPN
admet-3065	1111	39	prouza	prouza	PROPN
admet-3065	1111	40	,	,	PUNCT
admet-3065	1111	41	m.	m.	NOUN
admet-3065	1111	42	suchanek	suchanek	NOUN
admet-3065	1111	43	,	,	PUNCT
admet-3065	1111	44	g.	g.	PROPN
admet-3065	1111	45	wozniak	wozniak	PROPN
admet-3065	1111	46	-	-	PUNCT
admet-3065	1111	47	knopp	knopp	PROPN
admet-3065	1111	48	,	,	PUNCT
admet-3065	1111	49	v.	v.	ADP
admet-3065	1111	50	horejsi	horejsi	PROPN
admet-3065	1111	51	,	,	PUNCT
admet-3065	1111	52	g.	g.	PROPN
admet-3065	1111	53	schabbauer	schabbauer	PROPN
admet-3065	1111	54	,	,	PUNCT
admet-3065	1111	55	a.	a.	PROPN
admet-3065	1111	56	cavaco	cavaco	PROPN
admet-3065	1111	57	-	-	PUNCT
admet-3065	1111	58	paulo	paulo	PROPN
admet-3065	1111	59	,	,	PUNCT
admet-3065	1111	60	h.	h.	PROPN
admet-3065	1111	61	stockinger	stockinger	PROPN
admet-3065	1111	62	.	.	PUNCT
admet-3065	1112	1	fab	fab	PROPN
admet-3065	1112	2	antibody	antibody	NOUN
admet-3065	1112	3	fragment	fragment	NOUN
admet-3065	1112	4	-	-	PUNCT
admet-3065	1112	5	functionalized	functionalize	VERB
admet-3065	1112	6	liposomes	liposome	NOUN
admet-3065	1112	7	for	for	ADP
admet-3065	1112	8	specific	specific	ADJ
admet-3065	1112	9	targeting	targeting	NOUN
admet-3065	1112	10	of	of	ADP
admet-3065	1112	11	antigen	antigen	NOUN
admet-3065	1112	12	-	-	PUNCT
admet-3065	1112	13	positive	positive	ADJ
admet-3065	1112	14	cells	cell	NOUN
admet-3065	1112	15	.	.	PUNCT
admet-3065	1113	1	nanomedicine	nanomedicine	NOUN
admet-3065	1113	2	:	:	PUNCT
admet-3065	1113	3	nanotechnology	nanotechnology	NOUN
admet-3065	1113	4	,	,	PUNCT
admet-3065	1113	5	biology	biology	NOUN
admet-3065	1113	6	and	and	CCONJ
admet-3065	1113	7	medicine	medicine	NOUN
admet-3065	1113	8	14	14	NUM
admet-3065	1113	9	(	(	PUNCT
admet-3065	1113	10	2018	2018	NUM
admet-3065	1113	11	)	)	PUNCT
admet-3065	1113	12	123	123	NUM
admet-3065	1113	13	-	-	SYM
admet-3065	1113	14	130	130	NUM
admet-3065	1113	15	.	.	PUNCT
admet-3065	1114	1	https://doi.org/10.1016/j.nano.2017.09.003	https://doi.org/10.1016/j.nano.2017.09.003	NUM
admet-3065	1114	2	[	[	X
admet-3065	1114	3	189	189	NUM
admet-3065	1114	4	]	]	PUNCT
admet-3065	1114	5	f.	f.	NOUN
admet-3065	1114	6	rommasi	rommasi	PROPN
admet-3065	1114	7	,	,	PUNCT
admet-3065	1114	8	n.	n.	PROPN
admet-3065	1114	9	esfandiari	esfandiari	PROPN
admet-3065	1114	10	.	.	PUNCT
admet-3065	1115	1	liposomal	liposomal	PROPN
admet-3065	1115	2	nanomedicine	nanomedicine	PROPN
admet-3065	1115	3	:	:	PUNCT
admet-3065	1115	4	applications	application	NOUN
admet-3065	1115	5	for	for	ADP
admet-3065	1115	6	drug	drug	NOUN
admet-3065	1115	7	delivery	delivery	NOUN
admet-3065	1115	8	in	in	ADP
admet-3065	1115	9	cancer	cancer	NOUN
admet-3065	1115	10	therapy	therapy	NOUN
admet-3065	1115	11	.	.	PUNCT
admet-3065	1116	1	nanoscale	nanoscale	NOUN
admet-3065	1116	2	research	research	NOUN
admet-3065	1116	3	letters	letter	NOUN
admet-3065	1116	4	16	16	NUM
admet-3065	1116	5	(	(	PUNCT
admet-3065	1116	6	2021	2021	NUM
admet-3065	1116	7	)	)	PUNCT
admet-3065	1116	8	95	95	NUM
admet-3065	1116	9	.	.	PUNCT
admet-3065	1117	1	https://doi.org/10.1186/s11671-021-03553-8	https://doi.org/10.1186/s11671-021-03553-8	NUM
admet-3065	1117	2	[	[	X
admet-3065	1117	3	190	190	NUM
admet-3065	1117	4	]	]	PUNCT
admet-3065	1117	5	a.	a.	NOUN
admet-3065	1117	6	adhikari	adhikari	PROPN
admet-3065	1117	7	,	,	PUNCT
admet-3065	1117	8	i.a	i.a	PROPN
admet-3065	1117	9	.	.	PROPN
admet-3065	1117	10	chen	chen	PROPN
admet-3065	1117	11	.	.	PUNCT
admet-3065	1118	1	antibody	antibody	NOUN
admet-3065	1118	2	-	-	PUNCT
admet-3065	1118	3	nanoparticle	nanoparticle	NOUN
admet-3065	1118	4	conjugates	conjugate	NOUN
admet-3065	1118	5	in	in	ADP
admet-3065	1118	6	therapy	therapy	NOUN
admet-3065	1118	7	:	:	PUNCT
admet-3065	1118	8	combining	combine	VERB
admet-3065	1118	9	the	the	DET
admet-3065	1118	10	best	good	ADJ
admet-3065	1118	11	of	of	ADP
admet-3065	1118	12	two	two	NUM
admet-3065	1118	13	worlds	world	NOUN
admet-3065	1118	14	.	.	PUNCT
admet-3065	1119	1	small	small	ADJ
admet-3065	1119	2	21	21	NUM
admet-3065	1119	3	(	(	PUNCT
admet-3065	1119	4	2025	2025	NUM
admet-3065	1119	5	)	)	PUNCT
admet-3065	1119	6	2409635	2409635	NUM
admet-3065	1119	7	.	.	PUNCT
admet-3065	1119	8	https://doi.org/10.1002/smll.202409635	https://doi.org/10.1002/smll.202409635	X
admet-3065	1120	1	[	[	X
admet-3065	1120	2	191	191	NUM
admet-3065	1120	3	]	]	PUNCT
admet-3065	1120	4	s.	s.	PROPN
admet-3065	1120	5	gera	gera	PROPN
admet-3065	1120	6	,	,	PUNCT
admet-3065	1120	7	e.	e.	PROPN
admet-3065	1120	8	kankuri	kankuri	PROPN
admet-3065	1120	9	,	,	PUNCT
admet-3065	1120	10	k.	k.	PROPN
admet-3065	1120	11	kogermann	kogermann	PROPN
admet-3065	1120	12	.	.	PUNCT
admet-3065	1121	1	antimicrobial	antimicrobial	ADJ
admet-3065	1121	2	peptides	peptide	NOUN
admet-3065	1121	3	unleashing	unleash	VERB
admet-3065	1121	4	their	their	PRON
admet-3065	1121	5	therapeutic	therapeutic	ADJ
admet-3065	1121	6	potential	potential	NOUN
admet-3065	1121	7	using	use	VERB
admet-3065	1121	8	nanotechnology	nanotechnology	NOUN
admet-3065	1121	9	.	.	PUNCT
admet-3065	1122	1	pharmacology	pharmacology	NOUN
admet-3065	1122	2	&	&	CCONJ
admet-3065	1122	3	therapeutics	therapeutic	NOUN
admet-3065	1122	4	232	232	NUM
admet-3065	1122	5	(	(	PUNCT
admet-3065	1122	6	2022	2022	NUM
admet-3065	1122	7	)	)	PUNCT
admet-3065	1122	8	107990	107990	NUM
admet-3065	1122	9	.	.	PUNCT
admet-3065	1123	1	https://doi.org/10.1016/j.pharmthera.2021.107990	https://doi.org/10.1016/j.pharmthera.2021.107990	PROPN
admet-3065	1123	2	[	[	X
admet-3065	1123	3	192	192	NUM
admet-3065	1123	4	]	]	X
admet-3065	1123	5	c.	c.	PROPN
admet-3065	1123	6	zylberberg	zylberberg	PROPN
admet-3065	1123	7	,	,	PUNCT
admet-3065	1123	8	k.	k.	PROPN
admet-3065	1123	9	gaskill	gaskill	PROPN
admet-3065	1123	10	,	,	PUNCT
admet-3065	1123	11	s.	s.	PROPN
admet-3065	1123	12	pasley	pasley	PROPN
admet-3065	1123	13	,	,	PUNCT
admet-3065	1123	14	s.	s.	PROPN
admet-3065	1123	15	matosevic	matosevic	PROPN
admet-3065	1123	16	.	.	PUNCT
admet-3065	1124	1	engineering	engineer	VERB
admet-3065	1124	2	liposomal	liposomal	ADJ
admet-3065	1124	3	nanoparticles	nanoparticle	NOUN
admet-3065	1124	4	for	for	ADP
admet-3065	1124	5	targeted	target	VERB
admet-3065	1124	6	gene	gene	NOUN
admet-3065	1124	7	therapy	therapy	NOUN
admet-3065	1124	8	.	.	PUNCT
admet-3065	1125	1	gene	gene	NOUN
admet-3065	1125	2	therapy	therapy	NOUN
admet-3065	1125	3	24	24	NUM
admet-3065	1125	4	(	(	PUNCT
admet-3065	1125	5	2017	2017	NUM
admet-3065	1125	6	)	)	PUNCT
admet-3065	1125	7	441	441	NUM
admet-3065	1125	8	-	-	SYM
admet-3065	1125	9	452	452	NUM
admet-3065	1125	10	.	.	PUNCT
admet-3065	1125	11	https://doi.org/10.1038/gt.2017.41	https://doi.org/10.1038/gt.2017.41	PUNCT
admet-3065	1126	1	[	[	X
admet-3065	1126	2	193	193	NUM
admet-3065	1126	3	]	]	PUNCT
admet-3065	1126	4	x.	x.	PROPN
admet-3065	1126	5	wei	wei	PROPN
admet-3065	1126	6	,	,	PUNCT
admet-3065	1126	7	j.	j.	PROPN
admet-3065	1126	8	gao	gao	PROPN
admet-3065	1126	9	,	,	PUNCT
admet-3065	1126	10	c.	c.	PROPN
admet-3065	1126	11	zhan	zhan	PROPN
admet-3065	1126	12	,	,	PUNCT
admet-3065	1126	13	c.	c.	PROPN
admet-3065	1126	14	xie	xie	PROPN
admet-3065	1126	15	,	,	PUNCT
admet-3065	1126	16	z.	z.	PROPN
admet-3065	1126	17	chai	chai	PROPN
admet-3065	1126	18	,	,	PUNCT
admet-3065	1126	19	d.	d.	PROPN
admet-3065	1126	20	ran	run	VERB
admet-3065	1126	21	,	,	PUNCT
admet-3065	1126	22	m.	m.	NOUN
admet-3065	1126	23	ying	ying	PROPN
admet-3065	1126	24	,	,	PUNCT
admet-3065	1126	25	p.	p.	PROPN
admet-3065	1126	26	zheng	zheng	PROPN
admet-3065	1126	27	,	,	PUNCT
admet-3065	1126	28	w.	w.	PROPN
admet-3065	1126	29	lu	lu	PROPN
admet-3065	1126	30	.	.	PUNCT
admet-3065	1126	31	liposome	liposome	NOUN
admet-3065	1126	32	-	-	PUNCT
admet-3065	1126	33	based	base	VERB
admet-3065	1126	34	glioma	glioma	NOUN
admet-3065	1126	35	targeted	target	VERB
admet-3065	1126	36	drug	drug	NOUN
admet-3065	1126	37	delivery	delivery	NOUN
admet-3065	1126	38	enabled	enable	VERB
admet-3065	1126	39	by	by	ADP
admet-3065	1126	40	stable	stable	ADJ
admet-3065	1126	41	peptide	peptide	NOUN
admet-3065	1126	42	ligands	ligand	NOUN
admet-3065	1126	43	.	.	PUNCT
admet-3065	1127	1	journal	journal	PROPN
admet-3065	1127	2	of	of	ADP
admet-3065	1127	3	controlled	control	VERB
admet-3065	1127	4	release	release	NOUN
admet-3065	1127	5	218	218	NUM
admet-3065	1127	6	(	(	PUNCT
admet-3065	1127	7	2015	2015	NUM
admet-3065	1127	8	)	)	PUNCT
admet-3065	1127	9	13	13	NUM
admet-3065	1127	10	-	-	SYM
admet-3065	1127	11	21	21	NUM
admet-3065	1127	12	.	.	PUNCT
admet-3065	1128	1	https://doi.org/10.1016/j.jconrel.2015.09.059	https://doi.org/10.1016/j.jconrel.2015.09.059	PROPN
admet-3065	1128	2	[	[	X
admet-3065	1128	3	194	194	NUM
admet-3065	1128	4	]	]	PUNCT
admet-3065	1128	5	s.	s.	PROPN
admet-3065	1128	6	majumdar	majumdar	PROPN
admet-3065	1128	7	,	,	PUNCT
admet-3065	1128	8	t.j	t.j	PROPN
admet-3065	1128	9	.	.	PROPN
admet-3065	1128	10	siahaan	siahaan	PROPN
admet-3065	1128	11	.	.	PUNCT
admet-3065	1129	1	peptide	peptide	NOUN
admet-3065	1129	2	-	-	PUNCT
admet-3065	1129	3	mediated	mediate	VERB
admet-3065	1129	4	targeted	target	VERB
admet-3065	1129	5	drug	drug	NOUN
admet-3065	1129	6	delivery	delivery	NOUN
admet-3065	1129	7	.	.	PUNCT
admet-3065	1130	1	medicinal	medicinal	ADJ
admet-3065	1130	2	research	research	NOUN
admet-3065	1130	3	reviews	review	NOUN
admet-3065	1130	4	32	32	NUM
admet-3065	1130	5	(	(	PUNCT
admet-3065	1130	6	2012	2012	NUM
admet-3065	1130	7	)	)	PUNCT
admet-3065	1130	8	637	637	NUM
admet-3065	1130	9	-	-	SYM
admet-3065	1130	10	658	658	NUM
admet-3065	1130	11	.	.	PUNCT
admet-3065	1131	1	https://doi.org/10.1002/med.20225	https://doi.org/10.1002/med.20225	PROPN
admet-3065	1132	1	[	[	X
admet-3065	1132	2	195	195	NUM
admet-3065	1132	3	]	]	X
admet-3065	1132	4	y.	y.	PROPN
admet-3065	1132	5	kato	kato	PROPN
admet-3065	1132	6	,	,	PUNCT
admet-3065	1132	7	y.	y.	PROPN
admet-3065	1132	8	sugiyama	sugiyama	PROPN
admet-3065	1132	9	.	.	PUNCT
admet-3065	1132	10	targeted	target	VERB
admet-3065	1132	11	delivery	delivery	NOUN
admet-3065	1132	12	of	of	ADP
admet-3065	1132	13	peptides	peptide	NOUN
admet-3065	1132	14	,	,	PUNCT
admet-3065	1132	15	proteins	protein	NOUN
admet-3065	1132	16	,	,	PUNCT
admet-3065	1132	17	and	and	CCONJ
admet-3065	1132	18	genes	gene	NOUN
admet-3065	1132	19	by	by	ADP
admet-3065	1132	20	receptor	receptor	NOUN
admet-3065	1132	21	-	-	PUNCT
admet-3065	1132	22	mediated	mediate	VERB
admet-3065	1132	23	endocytosis	endocytosis	NOUN
admet-3065	1132	24	.	.	PUNCT
admet-3065	1133	1	critical	critical	ADJ
admet-3065	1133	2	reviews	review	NOUN
admet-3065	1133	3	in	in	ADP
admet-3065	1133	4	therapeutic	therapeutic	ADJ
admet-3065	1133	5	drug	drug	NOUN
admet-3065	1133	6	carrier	carrier	NOUN
admet-3065	1133	7	systems	system	NOUN
admet-3065	1133	8	14	14	NUM
admet-3065	1133	9	(	(	PUNCT
admet-3065	1133	10	1997	1997	NUM
admet-3065	1133	11	)	)	PUNCT
admet-3065	1133	12	287	287	NUM
admet-3065	1133	13	-	-	SYM
admet-3065	1133	14	331	331	NUM
admet-3065	1133	15	.	.	PUNCT
admet-3065	1133	16	https://doi.org/10.1615/critrevtherdrugcarriersyst.v14.i3.30	https://doi.org/10.1615/critrevtherdrugcarriersyst.v14.i3.30	X
admet-3065	1134	1	[	[	X
admet-3065	1134	2	196	196	NUM
admet-3065	1134	3	]	]	X
admet-3065	1134	4	l.	l.	PROPN
admet-3065	1134	5	dang	dang	PROPN
admet-3065	1134	6	,	,	PUNCT
admet-3065	1134	7	j.	j.	PROPN
admet-3065	1134	8	liu	liu	PROPN
admet-3065	1134	9	,	,	PUNCT
admet-3065	1134	10	f.	f.	PROPN
admet-3065	1134	11	li	li	PROPN
admet-3065	1134	12	,	,	PUNCT
admet-3065	1134	13	l.	l.	PROPN
admet-3065	1134	14	wang	wang	PROPN
admet-3065	1134	15	,	,	PUNCT
admet-3065	1134	16	d.	d.	PROPN
admet-3065	1134	17	li	li	PROPN
admet-3065	1134	18	,	,	PUNCT
admet-3065	1134	19	b.	b.	PROPN
admet-3065	1134	20	guo	guo	PROPN
admet-3065	1134	21	,	,	PUNCT
admet-3065	1134	22	x.	x.	NOUN
admet-3065	1135	1	he	he	PRON
admet-3065	1135	2	,	,	PUNCT
admet-3065	1135	3	f.	f.	PROPN
admet-3065	1135	4	jiang	jiang	PROPN
admet-3065	1135	5	,	,	PUNCT
admet-3065	1135	6	c.	c.	PROPN
admet-3065	1135	7	liang	liang	PROPN
admet-3065	1135	8	,	,	PUNCT
admet-3065	1135	9	b.	b.	PROPN
admet-3065	1135	10	liu	liu	PROPN
admet-3065	1135	11	,	,	PUNCT
admet-3065	1135	12	s.a	s.a	PROPN
admet-3065	1135	13	.	.	PROPN
admet-3065	1135	14	badshah	badshah	PROPN
admet-3065	1135	15	,	,	PUNCT
admet-3065	1135	16	b.	b.	PROPN
admet-3065	1136	1	he	he	PRON
admet-3065	1136	2	,	,	PUNCT
admet-3065	1136	3	j.	j.	PROPN
admet-3065	1136	4	lu	lu	PROPN
admet-3065	1136	5	,	,	PUNCT
admet-3065	1136	6	c.	c.	PROPN
admet-3065	1136	7	lu	lu	PROPN
admet-3065	1136	8	,	,	PUNCT
admet-3065	1136	9	a.	a.	PROPN
admet-3065	1136	10	lu	lu	PROPN
admet-3065	1136	11	,	,	PUNCT
admet-3065	1136	12	g.	g.	PROPN
admet-3065	1136	13	zhang	zhang	PROPN
admet-3065	1136	14	.	.	PUNCT
admet-3065	1137	1	targeted	target	VERB
admet-3065	1137	2	delivery	delivery	NOUN
admet-3065	1137	3	systems	system	NOUN
admet-3065	1137	4	for	for	ADP
admet-3065	1137	5	molecular	molecular	ADJ
admet-3065	1137	6	therapy	therapy	NOUN
admet-3065	1137	7	in	in	ADP
admet-3065	1137	8	skeletal	skeletal	ADJ
admet-3065	1137	9	disorders	disorder	NOUN
admet-3065	1137	10	.	.	PUNCT
admet-3065	1138	1	international	international	ADJ
admet-3065	1138	2	journal	journal	NOUN
admet-3065	1138	3	of	of	ADP
admet-3065	1138	4	molecular	molecular	ADJ
admet-3065	1138	5	sciences	science	NOUN
admet-3065	1138	6	17	17	NUM
admet-3065	1138	7	(	(	PUNCT
admet-3065	1138	8	2016	2016	NUM
admet-3065	1138	9	)	)	PUNCT
admet-3065	1138	10	428	428	NUM
admet-3065	1138	11	.	.	PUNCT
admet-3065	1139	1	https://doi.org/10.3390/ijms17030428	https://doi.org/10.3390/ijms17030428	NOUN
admet-3065	1140	1	[	[	X
admet-3065	1140	2	197	197	NUM
admet-3065	1140	3	]	]	X
admet-3065	1140	4	g.	g.	PROPN
admet-3065	1140	5	li	li	PROPN
admet-3065	1140	6	,	,	PUNCT
admet-3065	1140	7	y.z	y.z	PROPN
admet-3065	1140	8	.	.	PROPN
admet-3065	1140	9	song	song	PROPN
admet-3065	1140	10	,	,	PUNCT
admet-3065	1140	11	z.j	z.j	PROPN
admet-3065	1140	12	.	.	PROPN
admet-3065	1140	13	huang	huang	PROPN
admet-3065	1140	14	,	,	PUNCT
admet-3065	1140	15	k.	k.	PROPN
admet-3065	1140	16	chen	chen	PROPN
admet-3065	1140	17	,	,	PUNCT
admet-3065	1141	1	d.w	d.w	PROPN
admet-3065	1141	2	.	.	PROPN
admet-3065	1142	1	chen	chen	PROPN
admet-3065	1142	2	,	,	PUNCT
admet-3065	1142	3	y.h	y.h	PROPN
admet-3065	1142	4	.	.	PROPN
admet-3065	1142	5	deng	deng	PROPN
admet-3065	1142	6	.	.	PROPN
admet-3065	1142	7	novel	novel	PROPN
admet-3065	1142	8	,	,	PUNCT
admet-3065	1142	9	nano	nano	NOUN
admet-3065	1142	10	-	-	PUNCT
admet-3065	1142	11	sized	sized	ADJ
admet-3065	1142	12	,	,	PUNCT
admet-3065	1142	13	liposome	liposome	NOUN
admet-3065	1142	14	-	-	PUNCT
admet-3065	1142	15	encapsulated	encapsulate	VERB
admet-3065	1142	16	polyamidoamine	polyamidoamine	NOUN
admet-3065	1142	17	dendrimer	dendrimer	NOUN
admet-3065	1142	18	derivatives	derivative	NOUN
admet-3065	1142	19	facilitate	facilitate	VERB
admet-3065	1142	20	tumour	tumour	NOUN
admet-3065	1142	21	targeting	target	VERB
admet-3065	1142	22	by	by	ADP
admet-3065	1142	23	overcoming	overcome	VERB
admet-3065	1142	24	the	the	DET
admet-3065	1142	25	polyethylene	polyethylene	NOUN
admet-3065	1142	26	glycol	glycol	NOUN
admet-3065	1142	27	dilemma	dilemma	NOUN
admet-3065	1142	28	and	and	CCONJ
admet-3065	1142	29	integrin	integrin	NOUN
admet-3065	1142	30	saturation	saturation	NOUN
admet-3065	1142	31	obstacle	obstacle	NOUN
admet-3065	1142	32	.	.	PUNCT
admet-3065	1143	1	journal	journal	PROPN
admet-3065	1143	2	of	of	ADP
admet-3065	1143	3	drug	drug	NOUN
admet-3065	1143	4	targeting	target	VERB
admet-3065	1143	5	25	25	NUM
admet-3065	1143	6	(	(	PUNCT
admet-3065	1143	7	2017	2017	NUM
admet-3065	1143	8	)	)	PUNCT
admet-3065	1143	9	734	734	NUM
admet-3065	1143	10	-	-	SYM
admet-3065	1143	11	746	746	NUM
admet-3065	1143	12	.	.	PUNCT
admet-3065	1144	1	https://doi.org/10.1080/1061186x.2017.1324860	https://doi.org/10.1080/1061186x.2017.1324860	NOUN
admet-3065	1144	2	[	[	X
admet-3065	1144	3	198	198	NUM
admet-3065	1144	4	]	]	PUNCT
admet-3065	1144	5	t.	t.	PROPN
admet-3065	1144	6	asai	asai	PROPN
admet-3065	1144	7	,	,	PUNCT
admet-3065	1144	8	n.	n.	PROPN
admet-3065	1144	9	oku	oku	PROPN
admet-3065	1144	10	.	.	PROPN
admet-3065	1144	11	liposomalized	liposomalize	VERB
admet-3065	1144	12	oligopeptides	oligopeptide	NOUN
admet-3065	1144	13	in	in	ADP
admet-3065	1144	14	cancer	cancer	NOUN
admet-3065	1144	15	therapy	therapy	NOUN
admet-3065	1144	16	.	.	PUNCT
admet-3065	1145	1	methods	method	NOUN
admet-3065	1145	2	in	in	ADP
admet-3065	1145	3	enzymology	enzymology	NOUN
admet-3065	1145	4	391	391	NUM
admet-3065	1145	5	(	(	PUNCT
admet-3065	1145	6	2005	2005	NUM
admet-3065	1145	7	)	)	PUNCT
admet-3065	1145	8	163	163	NUM
admet-3065	1145	9	-	-	SYM
admet-3065	1145	10	176	176	NUM
admet-3065	1145	11	.	.	PUNCT
admet-3065	1146	1	https://doi.org/10.1016/s0076-6879(05)91009-4	https://doi.org/10.1016/s0076-6879(05)91009-4	NOUN
admet-3065	1146	2	https://doi.org/10.1016/j.heliyon.2022.e09394	https://doi.org/10.1016/j.heliyon.2022.e09394	X
admet-3065	1146	3	https://doi.org/10.1038/s41435-020-0105-9	https://doi.org/10.1038/s41435-020-0105-9	NUM
admet-3065	1146	4	https://doi.org/10.3389/fimmu.2013.00302	https://doi.org/10.3389/fimmu.2013.00302	NOUN
admet-3065	1146	5	https://doi.org/10.1016/j.jconrel.2025.01.047	https://doi.org/10.1016/j.jconrel.2025.01.047	ADJ
admet-3065	1146	6	https://doi.org/10.1021/ar2000138	https://doi.org/10.1021/ar2000138	PROPN
admet-3065	1146	7	https://doi.org/10.1038/s41578-020-00269-6	https://doi.org/10.1038/s41578-020-00269-6	NUM
admet-3065	1146	8	https://doi.org/10.1038/s41578-020-00269-6	https://doi.org/10.1038/s41578-020-00269-6	NUM
admet-3065	1147	1	https://doi.org/10.1021/bi00517a043	https://doi.org/10.1021/bi00517a043	PROPN
admet-3065	1147	2	https://doi.org/10.1016/j.nano.2017.09.003	https://doi.org/10.1016/j.nano.2017.09.003	NOUN
admet-3065	1147	3	https://doi.org/10.1186/s11671-021-03553-8	https://doi.org/10.1186/s11671-021-03553-8	NUM
admet-3065	1147	4	https://doi.org/10.1002/smll.202409635	https://doi.org/10.1002/smll.202409635	ADP
admet-3065	1147	5	https://doi.org/10.1016/j.pharmthera.2021.107990	https://doi.org/10.1016/j.pharmthera.2021.107990	PROPN
admet-3065	1147	6	https://doi.org/10.1038/gt.2017.41	https://doi.org/10.1038/gt.2017.41	X
admet-3065	1147	7	https://doi.org/10.1016/j.jconrel.2015.09.059	https://doi.org/10.1016/j.jconrel.2015.09.059	VERB
admet-3065	1147	8	https://doi.org/10.1002/med.20225	https://doi.org/10.1002/med.20225	PROPN
admet-3065	1147	9	https://doi.org/10.1615/critrevtherdrugcarriersyst.v14.i3.30	https://doi.org/10.1615/critrevtherdrugcarriersyst.v14.i3.30	X
admet-3065	1147	10	https://doi.org/10.3390/ijms17030428	https://doi.org/10.3390/ijms17030428	NOUN
admet-3065	1147	11	https://doi.org/10.1080/1061186x.2017.1324860	https://doi.org/10.1080/1061186x.2017.1324860	PROPN
admet-3065	1147	12	https://doi.org/10.1016/s0076-6879(05)91009-4	https://doi.org/10.1016/s0076-6879(05)91009-4	PROPN
admet-3065	1147	13	e.	e.	PROPN
admet-3065	1147	14	j.	j.	PROPN
admet-3065	1147	15	saleh	saleh	PROPN
admet-3065	1147	16	et	et	PROPN
admet-3065	1147	17	al	al	PROPN
admet-3065	1147	18	.	.	PROPN
admet-3065	1147	19	admet	admet	PROPN
admet-3065	1147	20	&	&	CCONJ
admet-3065	1147	21	dmpk	dmpk	PROPN
admet-3065	1147	22	00(0	00(0	PROPN
admet-3065	1147	23	)	)	PUNCT
admet-3065	1147	24	(	(	PUNCT
admet-3065	1147	25	2025	2025	NUM
admet-3065	1147	26	)	)	PUNCT
admet-3065	1147	27	3065	3065	NUM
admet-3065	1147	28	30	30	NUM
admet-3065	1148	1	[	[	SYM
admet-3065	1148	2	199	199	NUM
admet-3065	1148	3	]	]	X
admet-3065	1148	4	o.	o.	PROPN
admet-3065	1148	5	al	al	PROPN
admet-3065	1148	6	musaimi	musaimi	PROPN
admet-3065	1148	7	,	,	PUNCT
admet-3065	1148	8	l.	l.	PROPN
admet-3065	1148	9	lombardi	lombardi	PROPN
admet-3065	1148	10	,	,	PUNCT
admet-3065	1148	11	d.r	d.r	PROPN
admet-3065	1148	12	.	.	PROPN
admet-3065	1148	13	williams	williams	PROPN
admet-3065	1148	14	,	,	PUNCT
admet-3065	1148	15	f.	f.	PROPN
admet-3065	1148	16	albericio	albericio	PROPN
admet-3065	1148	17	.	.	PUNCT
admet-3065	1149	1	strategies	strategy	NOUN
admet-3065	1149	2	for	for	ADP
admet-3065	1149	3	improving	improve	VERB
admet-3065	1149	4	peptide	peptide	ADJ
admet-3065	1149	5	stability	stability	NOUN
admet-3065	1149	6	and	and	CCONJ
admet-3065	1149	7	delivery	delivery	NOUN
admet-3065	1149	8	.	.	PUNCT
admet-3065	1150	1	pharmaceuticals	pharmaceutical	NOUN
admet-3065	1150	2	15	15	NUM
admet-3065	1150	3	(	(	PUNCT
admet-3065	1150	4	2022	2022	NUM
admet-3065	1150	5	)	)	PUNCT
admet-3065	1150	6	1283	1283	NUM
admet-3065	1150	7	.	.	PUNCT
admet-3065	1151	1	https://doi.org/10.3390/ph15101283	https://doi.org/10.3390/ph15101283	PRON
admet-3065	1152	1	[	[	X
admet-3065	1152	2	200	200	NUM
admet-3065	1152	3	]	]	PUNCT
admet-3065	1152	4	z.	z.	PROPN
admet-3065	1152	5	dongrui	dongrui	PROPN
admet-3065	1152	6	,	,	PUNCT
admet-3065	1152	7	m.	m.	NOUN
admet-3065	1152	8	miyamoto	miyamoto	PROPN
admet-3065	1152	9	,	,	PUNCT
admet-3065	1152	10	h.	h.	PROPN
admet-3065	1152	11	yokoo	yokoo	PROPN
admet-3065	1152	12	,	,	PUNCT
admet-3065	1152	13	y.	y.	PROPN
admet-3065	1152	14	demizu	demizu	PROPN
admet-3065	1152	15	.	.	PUNCT
admet-3065	1153	1	innovative	innovative	ADJ
admet-3065	1153	2	peptide	peptide	NOUN
admet-3065	1153	3	architectures	architecture	NOUN
admet-3065	1153	4	:	:	PUNCT
admet-3065	1153	5	advancements	advancement	NOUN
admet-3065	1153	6	in	in	ADP
admet-3065	1153	7	foldamers	foldamer	NOUN
admet-3065	1153	8	and	and	CCONJ
admet-3065	1153	9	stapled	staple	VERB
admet-3065	1153	10	peptides	peptide	NOUN
admet-3065	1153	11	for	for	ADP
admet-3065	1153	12	drug	drug	NOUN
admet-3065	1153	13	discovery	discovery	NOUN
admet-3065	1153	14	.	.	PUNCT
admet-3065	1154	1	expert	expert	ADJ
admet-3065	1154	2	opinion	opinion	NOUN
admet-3065	1154	3	on	on	ADP
admet-3065	1154	4	drug	drug	NOUN
admet-3065	1154	5	discovery	discovery	NOUN
admet-3065	1154	6	19	19	NUM
admet-3065	1154	7	(	(	PUNCT
admet-3065	1154	8	2024	2024	NUM
admet-3065	1154	9	)	)	PUNCT
admet-3065	1154	10	699723	699723	NUM
admet-3065	1154	11	.	.	PUNCT
admet-3065	1155	1	https://doi.org/10.1080/17460441.2024.2350568	https://doi.org/10.1080/17460441.2024.2350568	PROPN
admet-3065	1156	1	[	[	X
admet-3065	1156	2	201	201	NUM
admet-3065	1156	3	]	]	PUNCT
admet-3065	1156	4	z.	z.	PROPN
admet-3065	1156	5	frost	frost	PROPN
admet-3065	1156	6	,	,	PUNCT
admet-3065	1156	7	s.	s.	PROPN
admet-3065	1156	8	bakhit	bakhit	PROPN
admet-3065	1156	9	,	,	PUNCT
admet-3065	1156	10	c.n	c.n	PROPN
admet-3065	1156	11	.	.	PROPN
admet-3065	1156	12	amaefuna	amaefuna	PROPN
admet-3065	1156	13	,	,	PUNCT
admet-3065	1156	14	r.v	r.v	PROPN
admet-3065	1156	15	.	.	PROPN
admet-3065	1156	16	powers	power	NOUN
admet-3065	1156	17	,	,	PUNCT
admet-3065	1156	18	k.v	k.v	PROPN
admet-3065	1156	19	.	.	PROPN
admet-3065	1156	20	ramana	ramana	PROPN
admet-3065	1156	21	.	.	PUNCT
admet-3065	1157	1	recent	recent	ADJ
admet-3065	1157	2	advances	advance	NOUN
admet-3065	1157	3	on	on	ADP
admet-3065	1157	4	the	the	DET
admet-3065	1157	5	role	role	NOUN
admet-3065	1157	6	of	of	ADP
admet-3065	1157	7	b	b	NOUN
admet-3065	1157	8	vitamins	vitamin	NOUN
admet-3065	1157	9	in	in	ADP
admet-3065	1157	10	cancer	cancer	NOUN
admet-3065	1157	11	prevention	prevention	NOUN
admet-3065	1157	12	and	and	CCONJ
admet-3065	1157	13	progression	progression	NOUN
admet-3065	1157	14	.	.	PUNCT
admet-3065	1158	1	international	international	ADJ
admet-3065	1158	2	journal	journal	NOUN
admet-3065	1158	3	of	of	ADP
admet-3065	1158	4	molecular	molecular	ADJ
admet-3065	1158	5	sciences	science	NOUN
admet-3065	1158	6	26	26	NUM
admet-3065	1158	7	(	(	PUNCT
admet-3065	1158	8	2025	2025	NUM
admet-3065	1158	9	)	)	PUNCT
admet-3065	1158	10	1967	1967	NUM
admet-3065	1158	11	.	.	PUNCT
admet-3065	1159	1	https://doi.org/10.3390/ijms26051967	https://doi.org/10.3390/ijms26051967	PROPN
admet-3065	1160	1	[	[	X
admet-3065	1160	2	202	202	NUM
admet-3065	1160	3	]	]	X
admet-3065	1160	4	h.j	h.j	PROPN
admet-3065	1160	5	.	.	PROPN
admet-3065	1160	6	van	van	PROPN
admet-3065	1160	7	de	de	PROPN
admet-3065	1160	8	roovaart	roovaart	PROPN
admet-3065	1160	9	,	,	PUNCT
admet-3065	1160	10	m.m	m.m	PROPN
admet-3065	1160	11	.	.	PROPN
admet-3065	1160	12	stevens	stevens	PROPN
admet-3065	1160	13	,	,	PUNCT
admet-3065	1160	14	a.e	a.e	PROPN
admet-3065	1160	15	.	.	PROPN
admet-3065	1160	16	goodridge	goodridge	PROPN
admet-3065	1160	17	,	,	PUNCT
admet-3065	1160	18	k.r	k.r	PROPN
admet-3065	1160	19	.	.	PROPN
admet-3065	1160	20	baden	baden	PROPN
admet-3065	1160	21	,	,	PUNCT
admet-3065	1160	22	b.g	b.g	PROPN
admet-3065	1160	23	.	.	PROPN
admet-3065	1160	24	sibbitt	sibbitt	PROPN
admet-3065	1160	25	,	,	PUNCT
admet-3065	1160	26	e.	e.	PROPN
admet-3065	1160	27	delaney	delaney	PROPN
admet-3065	1160	28	,	,	PUNCT
admet-3065	1160	29	j.	j.	PROPN
admet-3065	1160	30	haluschak	haluschak	PROPN
admet-3065	1160	31	,	,	PUNCT
admet-3065	1160	32	s.	s.	PROPN
admet-3065	1160	33	kathula	kathula	PROPN
admet-3065	1160	34	,	,	PUNCT
admet-3065	1160	35	a.m.h	a.m.h	PROPN
admet-3065	1160	36	.	.	PUNCT
admet-3065	1161	1	chen	chen	PROPN
admet-3065	1161	2	.	.	PUNCT
admet-3065	1162	1	safety	safety	NOUN
admet-3065	1162	2	and	and	CCONJ
admet-3065	1162	3	efficacy	efficacy	NOUN
admet-3065	1162	4	of	of	ADP
admet-3065	1162	5	vitamin	vitamin	PROPN
admet-3065	1162	6	b	b	PROPN
admet-3065	1162	7	in	in	ADP
admet-3065	1162	8	cancer	cancer	NOUN
admet-3065	1162	9	treatments	treatment	NOUN
admet-3065	1162	10	:	:	PUNCT
admet-3065	1162	11	a	a	DET
admet-3065	1162	12	systematic	systematic	ADJ
admet-3065	1162	13	review	review	NOUN
admet-3065	1162	14	.	.	PUNCT
admet-3065	1163	1	journal	journal	NOUN
admet-3065	1163	2	of	of	ADP
admet-3065	1163	3	oncology	oncology	NOUN
admet-3065	1163	4	pharmacy	pharmacy	NOUN
admet-3065	1163	5	practice	practice	NOUN
admet-3065	1163	6	30	30	NUM
admet-3065	1163	7	(	(	PUNCT
admet-3065	1163	8	2024	2024	NUM
admet-3065	1163	9	)	)	PUNCT
admet-3065	1163	10	451	451	NUM
admet-3065	1163	11	-	-	SYM
admet-3065	1163	12	463	463	NUM
admet-3065	1163	13	.	.	PUNCT
admet-3065	1164	1	https://doi.org/10.1177/10781552231178686	https://doi.org/10.1177/10781552231178686	NOUN
admet-3065	1165	1	[	[	X
admet-3065	1165	2	203	203	NUM
admet-3065	1165	3	]	]	PUNCT
admet-3065	1165	4	w.	w.	PROPN
admet-3065	1165	5	weecharangsan	weecharangsan	PROPN
admet-3065	1165	6	,	,	PUNCT
admet-3065	1165	7	b.	b.	PROPN
admet-3065	1165	8	yu	yu	PROPN
admet-3065	1165	9	,	,	PUNCT
admet-3065	1165	10	y.	y.	PROPN
admet-3065	1165	11	zheng	zheng	PROPN
admet-3065	1165	12	,	,	PUNCT
admet-3065	1165	13	s.	s.	PROPN
admet-3065	1165	14	liu	liu	PROPN
admet-3065	1165	15	,	,	PUNCT
admet-3065	1165	16	j.x	j.x	PROPN
admet-3065	1165	17	.	.	PROPN
admet-3065	1165	18	pang	pang	PROPN
admet-3065	1165	19	,	,	PUNCT
admet-3065	1165	20	l.j	l.j	PROPN
admet-3065	1165	21	.	.	PROPN
admet-3065	1165	22	lee	lee	PROPN
admet-3065	1165	23	,	,	PUNCT
admet-3065	1165	24	g.	g.	PROPN
admet-3065	1165	25	marcucci	marcucci	PROPN
admet-3065	1165	26	,	,	PUNCT
admet-3065	1165	27	r.j	r.j	PROPN
admet-3065	1165	28	.	.	PROPN
admet-3065	1165	29	lee	lee	PROPN
admet-3065	1165	30	.	.	PROPN
admet-3065	1166	1	efficient	efficient	ADJ
admet-3065	1166	2	delivery	delivery	NOUN
admet-3065	1166	3	of	of	ADP
admet-3065	1166	4	antisense	antisense	NOUN
admet-3065	1166	5	oligodeoxyribonucleotide	oligodeoxyribonucleotide	NOUN
admet-3065	1166	6	g3139	g3139	PROPN
admet-3065	1166	7	by	by	ADP
admet-3065	1166	8	human	human	ADJ
admet-3065	1166	9	serum	serum	NOUN
admet-3065	1166	10	albumin	albumin	NOUN
admet-3065	1166	11	-	-	PUNCT
admet-3065	1166	12	coated	coat	VERB
admet-3065	1166	13	liposomes	liposome	NOUN
admet-3065	1166	14	.	.	PUNCT
admet-3065	1167	1	molecular	molecular	ADJ
admet-3065	1167	2	pharmaceutics	pharmaceutic	NOUN
admet-3065	1167	3	6	6	NUM
admet-3065	1167	4	(	(	PUNCT
admet-3065	1167	5	2009	2009	NUM
admet-3065	1167	6	)	)	PUNCT
admet-3065	1167	7	1848	1848	NUM
admet-3065	1167	8	-	-	SYM
admet-3065	1167	9	1855	1855	NUM
admet-3065	1167	10	.	.	PUNCT
admet-3065	1168	1	https://doi.org/10.1021/mp900150	https://doi.org/10.1021/mp900150	NOUN
admet-3065	1168	2	g	g	PROPN
admet-3065	1168	3	[	[	X
admet-3065	1168	4	204	204	NUM
admet-3065	1168	5	]	]	PUNCT
admet-3065	1168	6	l.	l.	PROPN
admet-3065	1168	7	yang	yang	PROPN
admet-3065	1168	8	,	,	PUNCT
admet-3065	1168	9	j.	j.	PROPN
admet-3065	1168	10	li	li	PROPN
admet-3065	1168	11	,	,	PUNCT
admet-3065	1168	12	w.	w.	PROPN
admet-3065	1168	13	zhou	zhou	PROPN
admet-3065	1168	14	,	,	PUNCT
admet-3065	1168	15	x.	x.	PROPN
admet-3065	1168	16	yuan	yuan	PROPN
admet-3065	1168	17	,	,	PUNCT
admet-3065	1168	18	s.	s.	PROPN
admet-3065	1168	19	li	li	PROPN
admet-3065	1168	20	.	.	PROPN
admet-3065	1168	21	targeted	target	VERB
admet-3065	1168	22	delivery	delivery	NOUN
admet-3065	1168	23	of	of	ADP
admet-3065	1168	24	antisense	antisense	NOUN
admet-3065	1168	25	oligodeoxynucleotides	oligodeoxynucleotide	NOUN
admet-3065	1168	26	to	to	PART
admet-3065	1168	27	folate	folate	VERB
admet-3065	1168	28	receptor	receptor	NOUN
admet-3065	1168	29	-	-	PUNCT
admet-3065	1168	30	overexpressing	overexpresse	VERB
admet-3065	1168	31	tumor	tumor	NOUN
admet-3065	1168	32	cells	cell	NOUN
admet-3065	1168	33	.	.	PUNCT
admet-3065	1169	1	journal	journal	PROPN
admet-3065	1169	2	of	of	ADP
admet-3065	1169	3	controlled	control	VERB
admet-3065	1169	4	release	release	NOUN
admet-3065	1169	5	95	95	NUM
admet-3065	1169	6	(	(	PUNCT
admet-3065	1169	7	2004	2004	NUM
admet-3065	1169	8	)	)	PUNCT
admet-3065	1169	9	321	321	NUM
admet-3065	1169	10	-	-	SYM
admet-3065	1169	11	331	331	NUM
admet-3065	1169	12	.	.	PUNCT
admet-3065	1170	1	https://doi.org/10.1016/j.jconrel.2003.11.021	https://doi.org/10.1016/j.jconrel.2003.11.021	PROPN
admet-3065	1170	2	[	[	X
admet-3065	1170	3	205	205	NUM
admet-3065	1170	4	]	]	X
admet-3065	1170	5	y.g	y.g	PROPN
admet-3065	1170	6	.	.	PROPN
admet-3065	1170	7	assaraf	assaraf	PROPN
admet-3065	1170	8	,	,	PUNCT
admet-3065	1170	9	c.p	c.p	PROPN
admet-3065	1170	10	.	.	PROPN
admet-3065	1170	11	leamon	leamon	PROPN
admet-3065	1170	12	,	,	PUNCT
admet-3065	1170	13	j.a	j.a	PROPN
admet-3065	1170	14	.	.	PROPN
admet-3065	1170	15	reddy	reddy	PROPN
admet-3065	1170	16	.	.	PUNCT
admet-3065	1171	1	the	the	DET
admet-3065	1171	2	folate	folate	NOUN
admet-3065	1171	3	receptor	receptor	NOUN
admet-3065	1171	4	as	as	ADP
admet-3065	1171	5	a	a	DET
admet-3065	1171	6	rational	rational	ADJ
admet-3065	1171	7	therapeutic	therapeutic	ADJ
admet-3065	1171	8	target	target	NOUN
admet-3065	1171	9	for	for	ADP
admet-3065	1171	10	personalized	personalized	ADJ
admet-3065	1171	11	cancer	cancer	NOUN
admet-3065	1171	12	treatment	treatment	NOUN
admet-3065	1171	13	.	.	PUNCT
admet-3065	1172	1	drug	drug	NOUN
admet-3065	1172	2	resistance	resistance	NOUN
admet-3065	1172	3	updates	update	VERB
admet-3065	1172	4	17	17	NUM
admet-3065	1172	5	(	(	PUNCT
admet-3065	1172	6	2014	2014	NUM
admet-3065	1172	7	)	)	PUNCT
admet-3065	1172	8	89	89	NUM
admet-3065	1172	9	-	-	SYM
admet-3065	1172	10	95	95	NUM
admet-3065	1172	11	.	.	PUNCT
admet-3065	1173	1	https://doi.org/10.1016/j.drup.2014.10.002	https://doi.org/10.1016/j.drup.2014.10.002	NOUN
admet-3065	1174	1	[	[	X
admet-3065	1174	2	206	206	NUM
admet-3065	1174	3	]	]	PUNCT
admet-3065	1174	4	j.	j.	PROPN
admet-3065	1174	5	sudimack	sudimack	PROPN
admet-3065	1174	6	,	,	PUNCT
admet-3065	1174	7	r.j	r.j	PROPN
admet-3065	1174	8	.	.	PROPN
admet-3065	1174	9	lee	lee	PROPN
admet-3065	1174	10	.	.	PROPN
admet-3065	1174	11	targeted	target	VERB
admet-3065	1174	12	drug	drug	NOUN
admet-3065	1174	13	delivery	delivery	NOUN
admet-3065	1174	14	via	via	ADP
admet-3065	1174	15	the	the	DET
admet-3065	1174	16	folate	folate	NOUN
admet-3065	1174	17	receptor	receptor	NOUN
admet-3065	1174	18	.	.	PUNCT
admet-3065	1175	1	advanced	advanced	ADJ
admet-3065	1175	2	drug	drug	NOUN
admet-3065	1175	3	delivery	delivery	NOUN
admet-3065	1175	4	reviews	review	VERB
admet-3065	1175	5	41	41	NUM
admet-3065	1175	6	(	(	PUNCT
admet-3065	1175	7	2000	2000	NUM
admet-3065	1175	8	)	)	PUNCT
admet-3065	1175	9	147	147	NUM
admet-3065	1175	10	-	-	SYM
admet-3065	1175	11	162	162	NUM
admet-3065	1175	12	.	.	PUNCT
admet-3065	1176	1	https://doi.org/10.1016/s0169-409x(99)00062-9	https://doi.org/10.1016/s0169-409x(99)00062-9	NOUN
admet-3065	1176	2	[	[	X
admet-3065	1176	3	207	207	NUM
admet-3065	1176	4	]	]	X
admet-3065	1176	5	c.p	c.p	PROPN
admet-3065	1176	6	.	.	PROPN
admet-3065	1176	7	leamon	leamon	PROPN
admet-3065	1176	8	,	,	PUNCT
admet-3065	1176	9	s.r	s.r	PROPN
admet-3065	1176	10	.	.	PROPN
admet-3065	1176	11	cooper	cooper	PROPN
admet-3065	1176	12	,	,	PUNCT
admet-3065	1176	13	g.e	g.e	PROPN
admet-3065	1176	14	.	.	PROPN
admet-3065	1176	15	hardee	hardee	PROPN
admet-3065	1176	16	.	.	PUNCT
admet-3065	1177	1	folate	folate	NOUN
admet-3065	1177	2	-	-	PUNCT
admet-3065	1177	3	liposome	liposome	NOUN
admet-3065	1177	4	-	-	PUNCT
admet-3065	1177	5	mediated	mediate	VERB
admet-3065	1177	6	antisense	antisense	NOUN
admet-3065	1177	7	oligodeoxynucleotide	oligodeoxynucleotide	NOUN
admet-3065	1177	8	targeting	target	VERB
admet-3065	1177	9	to	to	ADP
admet-3065	1177	10	cancer	cancer	NOUN
admet-3065	1177	11	cells	cell	NOUN
admet-3065	1177	12	:	:	PUNCT
admet-3065	1177	13	evaluation	evaluation	NOUN
admet-3065	1177	14	in	in	ADP
admet-3065	1177	15	vitro	vitro	X
admet-3065	1177	16	and	and	CCONJ
admet-3065	1177	17	in	in	ADP
admet-3065	1177	18	vivo	vivo	NOUN
admet-3065	1177	19	.	.	PUNCT
admet-3065	1178	1	bioconjugate	bioconjugate	NOUN
admet-3065	1178	2	chemistry	chemistry	NOUN
admet-3065	1178	3	14	14	NUM
admet-3065	1178	4	(	(	PUNCT
admet-3065	1178	5	2003	2003	NUM
admet-3065	1178	6	)	)	PUNCT
admet-3065	1178	7	738	738	NUM
admet-3065	1178	8	-	-	SYM
admet-3065	1178	9	747	747	NUM
admet-3065	1178	10	.	.	PUNCT
admet-3065	1179	1	https://doi.org/10.1021/bc020089	https://doi.org/10.1021/bc020089	PROPN
admet-3065	1179	2	t	t	NOUN
admet-3065	1179	3	[	[	X
admet-3065	1179	4	208	208	NUM
admet-3065	1179	5	]	]	PUNCT
admet-3065	1179	6	x.	x.	PROPN
admet-3065	1179	7	chen	chen	PROPN
admet-3065	1179	8	,	,	PUNCT
admet-3065	1179	9	x.	x.	PROPN
admet-3065	1179	10	wang	wang	PROPN
admet-3065	1179	11	,	,	PUNCT
admet-3065	1179	12	y.	y.	PROPN
admet-3065	1179	13	wang	wang	PROPN
admet-3065	1179	14	,	,	PUNCT
admet-3065	1179	15	l.	l.	PROPN
admet-3065	1179	16	yang	yang	PROPN
admet-3065	1179	17	,	,	PUNCT
admet-3065	1179	18	j.	j.	PROPN
admet-3065	1179	19	hu	hu	PROPN
admet-3065	1179	20	,	,	PUNCT
admet-3065	1179	21	w.	w.	PROPN
admet-3065	1179	22	xiao	xiao	PROPN
admet-3065	1179	23	,	,	PUNCT
admet-3065	1179	24	a.	a.	NOUN
admet-3065	1179	25	fu	fu	PROPN
admet-3065	1179	26	,	,	PUNCT
admet-3065	1179	27	l.	l.	PROPN
admet-3065	1179	28	cai	cai	PROPN
admet-3065	1179	29	,	,	PUNCT
admet-3065	1179	30	x.	x.	PROPN
admet-3065	1179	31	li	li	PROPN
admet-3065	1179	32	,	,	PUNCT
admet-3065	1179	33	x.	x.	NOUN
admet-3065	1179	34	ye	ye	PROPN
admet-3065	1179	35	,	,	PUNCT
admet-3065	1179	36	y.	y.	PROPN
admet-3065	1179	37	liu	liu	PROPN
admet-3065	1179	38	,	,	PUNCT
admet-3065	1179	39	w.	w.	PROPN
admet-3065	1179	40	wu	wu	PROPN
admet-3065	1179	41	,	,	PUNCT
admet-3065	1179	42	x.	x.	PROPN
admet-3065	1179	43	shao	shao	PROPN
admet-3065	1179	44	,	,	PUNCT
admet-3065	1179	45	y.	y.	PROPN
admet-3065	1179	46	mao	mao	PROPN
admet-3065	1179	47	,	,	PUNCT
admet-3065	1179	48	y.	y.	PROPN
admet-3065	1179	49	wei	wei	PROPN
admet-3065	1179	50	,	,	PUNCT
admet-3065	1179	51	l.	l.	PROPN
admet-3065	1179	52	chen	chen	PROPN
admet-3065	1179	53	.	.	PUNCT
admet-3065	1180	1	improved	improve	VERB
admet-3065	1180	2	tumor	tumor	NOUN
admet-3065	1180	3	-	-	PUNCT
admet-3065	1180	4	targeting	target	VERB
admet-3065	1180	5	drug	drug	NOUN
admet-3065	1180	6	delivery	delivery	NOUN
admet-3065	1180	7	and	and	CCONJ
admet-3065	1180	8	therapeutic	therapeutic	ADJ
admet-3065	1180	9	efficacy	efficacy	NOUN
admet-3065	1180	10	by	by	ADP
admet-3065	1180	11	cationic	cationic	ADJ
admet-3065	1180	12	liposome	liposome	NOUN
admet-3065	1180	13	modified	modify	VERB
admet-3065	1180	14	with	with	ADP
admet-3065	1180	15	truncated	truncate	VERB
admet-3065	1180	16	bfgf	bfgf	NOUN
admet-3065	1180	17	peptide	peptide	NOUN
admet-3065	1180	18	.	.	PUNCT
admet-3065	1181	1	journal	journal	NOUN
admet-3065	1181	2	of	of	ADP
admet-3065	1181	3	controlled	control	VERB
admet-3065	1181	4	release	release	NOUN
admet-3065	1181	5	145	145	NUM
admet-3065	1181	6	(	(	PUNCT
admet-3065	1181	7	2010	2010	NUM
admet-3065	1181	8	)	)	PUNCT
admet-3065	1181	9	17	17	NUM
admet-3065	1181	10	-	-	SYM
admet-3065	1181	11	25	25	NUM
admet-3065	1181	12	.	.	PUNCT
admet-3065	1182	1	https://doi.org/10.1016/j.jconrel.2010.03.007	https://doi.org/10.1016/j.jconrel.2010.03.007	VERB
admet-3065	1182	2	[	[	X
admet-3065	1182	3	209	209	NUM
admet-3065	1182	4	]	]	X
admet-3065	1182	5	l.	l.	PROPN
admet-3065	1182	6	sercombe	sercombe	PROPN
admet-3065	1182	7	,	,	PUNCT
admet-3065	1182	8	t.	t.	PROPN
admet-3065	1182	9	veerati	veerati	PROPN
admet-3065	1182	10	,	,	PUNCT
admet-3065	1182	11	f.	f.	PROPN
admet-3065	1182	12	moheimani	moheimani	PROPN
admet-3065	1182	13	,	,	PUNCT
admet-3065	1182	14	s.y	s.y	PROPN
admet-3065	1182	15	.	.	PROPN
admet-3065	1182	16	wu	wu	PROPN
admet-3065	1182	17	,	,	PUNCT
admet-3065	1182	18	a.k	a.k	PROPN
admet-3065	1182	19	.	.	PROPN
admet-3065	1182	20	sood	sood	PROPN
admet-3065	1182	21	,	,	PUNCT
admet-3065	1182	22	s.	s.	PROPN
admet-3065	1182	23	hua	hua	PROPN
admet-3065	1182	24	.	.	PROPN
admet-3065	1182	25	advances	advance	NOUN
admet-3065	1182	26	and	and	CCONJ
admet-3065	1182	27	challenges	challenge	NOUN
admet-3065	1182	28	of	of	ADP
admet-3065	1182	29	liposome	liposome	NOUN
admet-3065	1182	30	assisted	assist	VERB
admet-3065	1182	31	drug	drug	NOUN
admet-3065	1182	32	delivery	delivery	NOUN
admet-3065	1182	33	.	.	PUNCT
admet-3065	1183	1	frontiers	frontier	NOUN
admet-3065	1183	2	in	in	ADP
admet-3065	1183	3	pharmacology	pharmacology	NOUN
admet-3065	1183	4	6	6	NUM
admet-3065	1183	5	(	(	PUNCT
admet-3065	1183	6	2015	2015	NUM
admet-3065	1183	7	)	)	PUNCT
admet-3065	1183	8	00286	00286	NUM
admet-3065	1183	9	.	.	PUNCT
admet-3065	1184	1	https://doi.org/10.3389/fphar.2015.00286	https://doi.org/10.3389/fphar.2015.00286	PROPN
admet-3065	1184	2	[	[	X
admet-3065	1184	3	210	210	NUM
admet-3065	1184	4	]	]	X
admet-3065	1184	5	h.l	h.l	PROPN
admet-3065	1184	6	.	.	PROPN
admet-3065	1184	7	zhang	zhang	PROPN
admet-3065	1184	8	,	,	PUNCT
admet-3065	1184	9	c.	c.	PROPN
admet-3065	1184	10	lv	lv	PROPN
admet-3065	1184	11	,	,	PUNCT
admet-3065	1184	12	z.h	z.h	PROPN
admet-3065	1184	13	.	.	PROPN
admet-3065	1184	14	li	li	PROPN
admet-3065	1184	15	,	,	PUNCT
admet-3065	1184	16	s.	s.	PROPN
admet-3065	1184	17	jiang	jiang	PROPN
admet-3065	1184	18	,	,	PUNCT
admet-3065	1184	19	d.	d.	PROPN
admet-3065	1184	20	cai	cai	PROPN
admet-3065	1184	21	,	,	PUNCT
admet-3065	1184	22	s.s	s.s	PROPN
admet-3065	1184	23	.	.	PROPN
admet-3065	1184	24	liu	liu	PROPN
admet-3065	1184	25	,	,	PUNCT
admet-3065	1184	26	t.	t.	PROPN
admet-3065	1184	27	wang	wang	PROPN
admet-3065	1184	28	,	,	PUNCT
admet-3065	1184	29	k.h	k.h	PROPN
admet-3065	1184	30	.	.	PROPN
admet-3065	1184	31	zhang	zhang	PROPN
admet-3065	1184	32	.	.	PUNCT
admet-3065	1185	1	analysis	analysis	NOUN
admet-3065	1185	2	of	of	ADP
admet-3065	1185	3	aptamer	aptamer	NOUN
admet-3065	1185	4	-	-	PUNCT
admet-3065	1185	5	target	target	NOUN
admet-3065	1185	6	binding	binding	ADJ
admet-3065	1185	7	and	and	CCONJ
admet-3065	1185	8	molecular	molecular	ADJ
admet-3065	1185	9	mechanisms	mechanism	NOUN
admet-3065	1185	10	by	by	ADP
admet-3065	1185	11	thermofluorimetric	thermofluorimetric	ADJ
admet-3065	1185	12	analysis	analysis	NOUN
admet-3065	1185	13	and	and	CCONJ
admet-3065	1185	14	molecular	molecular	ADJ
admet-3065	1185	15	dynamics	dynamic	NOUN
admet-3065	1185	16	simulation	simulation	NOUN
admet-3065	1185	17	.	.	PUNCT
admet-3065	1186	1	frontiers	frontier	NOUN
admet-3065	1186	2	in	in	ADP
admet-3065	1186	3	chemistry	chemistry	NOUN
admet-3065	1186	4	11	11	NUM
admet-3065	1186	5	(	(	PUNCT
admet-3065	1186	6	2023	2023	NUM
admet-3065	1186	7	)	)	PUNCT
admet-3065	1186	8	1144347	1144347	NUM
admet-3065	1186	9	.	.	PUNCT
admet-3065	1187	1	https://doi.org/10.3389/fchem.2023.1144347	https://doi.org/10.3389/fchem.2023.1144347	PROPN
admet-3065	1187	2	[	[	X
admet-3065	1187	3	211	211	NUM
admet-3065	1187	4	]	]	PUNCT
admet-3065	1187	5	z.	z.	PROPN
admet-3065	1187	6	bognár	bognár	PROPN
admet-3065	1187	7	,	,	PUNCT
admet-3065	1187	8	r.e	r.e	PROPN
admet-3065	1187	9	.	.	PROPN
admet-3065	1187	10	gyurcsányi	gyurcsányi	PROPN
admet-3065	1187	11	.	.	PUNCT
admet-3065	1188	1	aptamers	aptamer	NOUN
admet-3065	1188	2	against	against	ADP
admet-3065	1188	3	immunoglobulins	immunoglobulin	NOUN
admet-3065	1188	4	:	:	PUNCT
admet-3065	1188	5	design	design	NOUN
admet-3065	1188	6	,	,	PUNCT
admet-3065	1188	7	selection	selection	NOUN
admet-3065	1188	8	and	and	CCONJ
admet-3065	1188	9	bioanalytical	bioanalytical	ADJ
admet-3065	1188	10	applications	application	NOUN
admet-3065	1188	11	.	.	PUNCT
admet-3065	1189	1	international	international	ADJ
admet-3065	1189	2	journal	journal	NOUN
admet-3065	1189	3	of	of	ADP
admet-3065	1189	4	molecular	molecular	ADJ
admet-3065	1189	5	sciences	science	NOUN
admet-3065	1189	6	21	21	NUM
admet-3065	1189	7	(	(	PUNCT
admet-3065	1189	8	2020	2020	NUM
admet-3065	1189	9	)	)	PUNCT
admet-3065	1189	10	1	1	NUM
admet-3065	1189	11	-	-	SYM
admet-3065	1189	12	40	40	NUM
admet-3065	1189	13	.	.	PUNCT
admet-3065	1190	1	https://doi.org/10.3390/ijms21165748	https://doi.org/10.3390/ijms21165748	X
admet-3065	1190	2	[	[	X
admet-3065	1191	1	212	212	NUM
admet-3065	1191	2	]	]	PUNCT
admet-3065	1191	3	m.	m.	NOUN
admet-3065	1191	4	kim	kim	PROPN
admet-3065	1191	5	,	,	PUNCT
admet-3065	1191	6	j.s	j.s	PROPN
admet-3065	1191	7	.	.	PROPN
admet-3065	1191	8	lee	lee	PROPN
admet-3065	1191	9	,	,	PUNCT
admet-3065	1191	10	w.	w.	PROPN
admet-3065	1191	11	kim	kim	PROPN
admet-3065	1191	12	,	,	PUNCT
admet-3065	1191	13	j.h	j.h	PROPN
admet-3065	1191	14	.	.	PROPN
admet-3065	1191	15	lee	lee	PROPN
admet-3065	1191	16	,	,	PUNCT
admet-3065	1191	17	b.h	b.h	PROPN
admet-3065	1191	18	.	.	PROPN
admet-3065	1191	19	jun	jun	PROPN
admet-3065	1191	20	,	,	PUNCT
admet-3065	1191	21	k.s	k.s	PROPN
admet-3065	1191	22	.	.	PROPN
admet-3065	1191	23	kim	kim	PROPN
admet-3065	1191	24	,	,	PUNCT
admet-3065	1191	25	d.e	d.e	PROPN
admet-3065	1191	26	.	.	PROPN
admet-3065	1191	27	kim	kim	PROPN
admet-3065	1191	28	.	.	PUNCT
admet-3065	1192	1	aptamer	aptamer	PROPN
admet-3065	1192	2	-	-	PUNCT
admet-3065	1192	3	conjugated	conjugate	VERB
admet-3065	1192	4	nano	nano	NOUN
admet-3065	1192	5	-	-	PUNCT
admet-3065	1192	6	liposome	liposome	NOUN
admet-3065	1192	7	for	for	ADP
admet-3065	1192	8	immunogenic	immunogenic	ADJ
admet-3065	1192	9	chemotherapy	chemotherapy	NOUN
admet-3065	1192	10	with	with	ADP
admet-3065	1192	11	reversal	reversal	NOUN
admet-3065	1192	12	of	of	ADP
admet-3065	1192	13	immunosuppression	immunosuppression	NOUN
admet-3065	1192	14	.	.	PUNCT
admet-3065	1193	1	journal	journal	PROPN
admet-3065	1193	2	of	of	ADP
admet-3065	1193	3	controlled	control	VERB
admet-3065	1193	4	release	release	NOUN
admet-3065	1193	5	348	348	NUM
admet-3065	1193	6	(	(	PUNCT
admet-3065	1193	7	2022	2022	NUM
admet-3065	1193	8	)	)	PUNCT
admet-3065	1193	9	893	893	NUM
admet-3065	1193	10	-	-	SYM
admet-3065	1193	11	910	910	NUM
admet-3065	1193	12	.	.	PUNCT
admet-3065	1194	1	https://doi.org/10.1016/j.jconrel.2022.06.039	https://doi.org/10.1016/j.jconrel.2022.06.039	NOUN
admet-3065	1194	2	[	[	X
admet-3065	1194	3	213	213	NUM
admet-3065	1194	4	]	]	PUNCT
admet-3065	1194	5	g.	g.	PROPN
admet-3065	1194	6	zhou	zhou	PROPN
admet-3065	1194	7	,	,	PUNCT
admet-3065	1194	8	g.	g.	PROPN
admet-3065	1194	9	wilson	wilson	PROPN
admet-3065	1194	10	,	,	PUNCT
admet-3065	1194	11	l.	l.	PROPN
admet-3065	1194	12	hebbard	hebbard	PROPN
admet-3065	1194	13	,	,	PUNCT
admet-3065	1194	14	w.	w.	PROPN
admet-3065	1194	15	duan	duan	PROPN
admet-3065	1194	16	,	,	PUNCT
admet-3065	1194	17	c.	c.	PROPN
admet-3065	1194	18	liddle	liddle	PROPN
admet-3065	1194	19	,	,	PUNCT
admet-3065	1194	20	j.	j.	PROPN
admet-3065	1194	21	george	george	PROPN
admet-3065	1194	22	,	,	PUNCT
admet-3065	1194	23	l.	l.	PROPN
admet-3065	1194	24	qiao	qiao	PROPN
admet-3065	1194	25	.	.	PUNCT
admet-3065	1195	1	aptamers	aptamer	NOUN
admet-3065	1195	2	:	:	PUNCT
admet-3065	1195	3	a	a	DET
admet-3065	1195	4	promising	promising	ADJ
admet-3065	1195	5	chemical	chemical	NOUN
admet-3065	1195	6	antibody	antibody	NOUN
admet-3065	1195	7	for	for	ADP
admet-3065	1195	8	cancer	cancer	NOUN
admet-3065	1195	9	therapy	therapy	NOUN
admet-3065	1195	10	.	.	PUNCT
admet-3065	1196	1	oncotarget	oncotarget	VERB
admet-3065	1196	2	7	7	NUM
admet-3065	1196	3	(	(	PUNCT
admet-3065	1196	4	2016	2016	NUM
admet-3065	1196	5	)	)	PUNCT
admet-3065	1196	6	13446	13446	NUM
admet-3065	1196	7	-	-	SYM
admet-3065	1196	8	13463	13463	NUM
admet-3065	1196	9	.	.	PUNCT
admet-3065	1197	1	https://doi.org/10.18632/oncotarget.7178	https://doi.org/10.18632/oncotarget.7178	ADJ
admet-3065	1197	2	[	[	X
admet-3065	1197	3	214	214	NUM
admet-3065	1197	4	]	]	PUNCT
admet-3065	1197	5	x.	x.	PROPN
admet-3065	1197	6	li	li	PROPN
admet-3065	1197	7	,	,	PUNCT
admet-3065	1197	8	q.	q.	PROPN
admet-3065	1197	9	zhao	zhao	PROPN
admet-3065	1197	10	,	,	PUNCT
admet-3065	1197	11	l.	l.	PROPN
admet-3065	1197	12	qiu	qiu	PROPN
admet-3065	1197	13	.	.	PUNCT
admet-3065	1198	1	smart	smart	ADJ
admet-3065	1198	2	ligand	ligand	NOUN
admet-3065	1198	3	:	:	PUNCT
admet-3065	1198	4	aptamer	aptamer	NOUN
admet-3065	1198	5	-	-	PUNCT
admet-3065	1198	6	mediated	mediate	VERB
admet-3065	1198	7	targeted	target	VERB
admet-3065	1198	8	delivery	delivery	NOUN
admet-3065	1198	9	of	of	ADP
admet-3065	1198	10	chemotherapeutic	chemotherapeutic	ADJ
admet-3065	1198	11	drugs	drug	NOUN
admet-3065	1198	12	and	and	CCONJ
admet-3065	1198	13	sirna	sirna	PROPN
admet-3065	1198	14	for	for	ADP
admet-3065	1198	15	cancer	cancer	NOUN
admet-3065	1198	16	therapy	therapy	NOUN
admet-3065	1198	17	.	.	PUNCT
admet-3065	1199	1	journal	journal	PROPN
admet-3065	1199	2	of	of	ADP
admet-3065	1199	3	controlled	control	VERB
admet-3065	1199	4	release	release	NOUN
admet-3065	1199	5	171	171	NUM
admet-3065	1199	6	(	(	PUNCT
admet-3065	1199	7	2013	2013	NUM
admet-3065	1199	8	)	)	PUNCT
admet-3065	1199	9	152	152	NUM
admet-3065	1199	10	-	-	SYM
admet-3065	1199	11	162	162	NUM
admet-3065	1199	12	.	.	PUNCT
admet-3065	1200	1	https://doi.org/10.1016/j.jconrel.2013.06.006	https://doi.org/10.1016/j.jconrel.2013.06.006	NOUN
admet-3065	1200	2	[	[	X
admet-3065	1200	3	215	215	NUM
admet-3065	1200	4	]	]	PUNCT
admet-3065	1200	5	d.	d.	PROPN
admet-3065	1200	6	sanjanwala	sanjanwala	PROPN
admet-3065	1200	7	,	,	PUNCT
admet-3065	1200	8	v.	v.	PROPN
admet-3065	1200	9	patravale	patravale	PROPN
admet-3065	1200	10	.	.	PUNCT
admet-3065	1201	1	aptamers	aptamer	NOUN
admet-3065	1201	2	and	and	CCONJ
admet-3065	1201	3	nanobodies	nanobodie	NOUN
admet-3065	1201	4	as	as	ADP
admet-3065	1201	5	alternatives	alternative	NOUN
admet-3065	1201	6	to	to	ADP
admet-3065	1201	7	antibodies	antibody	NOUN
admet-3065	1201	8	for	for	ADP
admet-3065	1201	9	ligandtargeted	ligandtargete	VERB
admet-3065	1201	10	drug	drug	NOUN
admet-3065	1201	11	delivery	delivery	NOUN
admet-3065	1201	12	in	in	ADP
admet-3065	1201	13	cancer	cancer	NOUN
admet-3065	1201	14	.	.	PUNCT
admet-3065	1202	1	drug	drug	NOUN
admet-3065	1202	2	discovery	discovery	PROPN
admet-3065	1202	3	today	today	NOUN
admet-3065	1202	4	28	28	NUM
admet-3065	1202	5	(	(	PUNCT
admet-3065	1202	6	2023	2023	NUM
admet-3065	1202	7	)	)	PUNCT
admet-3065	1202	8	103550	103550	NUM
admet-3065	1202	9	.	.	PUNCT
admet-3065	1203	1	https://doi.org/10.1016/j.drudis.2023.103550	https://doi.org/10.1016/j.drudis.2023.103550	PROPN
admet-3065	1203	2	https://doi.org/10.3390/ph15101283	https://doi.org/10.3390/ph15101283	PRON
admet-3065	1204	1	https://doi.org/10.1080/17460441.2024.2350568	https://doi.org/10.1080/17460441.2024.2350568	PROPN
admet-3065	1205	1	https://doi.org/10.3390/ijms26051967	https://doi.org/10.3390/ijms26051967	PROPN
admet-3065	1205	2	https://doi.org/10.1177/10781552231178686	https://doi.org/10.1177/10781552231178686	VERB
admet-3065	1206	1	https://doi.org/10.1021/mp900150	https://doi.org/10.1021/mp900150	PROPN
admet-3065	1206	2	g	g	PROPN
admet-3065	1206	3	https://doi.org/10.1016/j.jconrel.2003.11.021	https://doi.org/10.1016/j.jconrel.2003.11.021	NOUN
admet-3065	1206	4	https://doi.org/10.1016/j.drup.2014.10.002	https://doi.org/10.1016/j.drup.2014.10.002	NOUN
admet-3065	1206	5	https://doi.org/10.1016/s0169-409x(99)00062-9	https://doi.org/10.1016/s0169-409x(99)00062-9	NOUN
admet-3065	1206	6	https://doi.org/10.1021/bc020089	https://doi.org/10.1021/bc020089	NOUN
admet-3065	1206	7	t	t	NOUN
admet-3065	1206	8	https://doi.org/10.1016/j.jconrel.2010.03.007	https://doi.org/10.1016/j.jconrel.2010.03.007	NOUN
admet-3065	1206	9	https://doi.org/10.3389/fphar.2015.00286	https://doi.org/10.3389/fphar.2015.00286	PROPN
admet-3065	1206	10	https://doi.org/10.3389/fchem.2023.1144347	https://doi.org/10.3389/fchem.2023.1144347	PROPN
admet-3065	1206	11	https://doi.org/10.3390/ijms21165748	https://doi.org/10.3390/ijms21165748	VERB
admet-3065	1206	12	https://doi.org/10.1016/j.jconrel.2022.06.039	https://doi.org/10.1016/j.jconrel.2022.06.039	NOUN
admet-3065	1206	13	https://doi.org/10.18632/oncotarget.7178	https://doi.org/10.18632/oncotarget.7178	ADJ
admet-3065	1206	14	https://doi.org/10.1016/j.jconrel.2013.06.006	https://doi.org/10.1016/j.jconrel.2013.06.006	X
admet-3065	1206	15	https://doi.org/10.1016/j.drudis.2023.103550	https://doi.org/10.1016/j.drudis.2023.103550	PROPN
admet-3065	1206	16	admet	admet	PROPN
admet-3065	1206	17	&	&	CCONJ
admet-3065	1206	18	dmpk	dmpk	PROPN
admet-3065	1206	19	00(0	00(0	PROPN
admet-3065	1206	20	)	)	PUNCT
admet-3065	1206	21	(	(	PUNCT
admet-3065	1206	22	2025	2025	NUM
admet-3065	1206	23	)	)	PUNCT
admet-3065	1206	24	3065	3065	NUM
admet-3065	1206	25	liposome	liposome	NOUN
admet-3065	1206	26	-	-	PUNCT
admet-3065	1206	27	mediated	mediate	VERB
admet-3065	1206	28	gene	gene	NOUN
admet-3065	1206	29	delivery	delivery	NOUN
admet-3065	1206	30	doi	doi	NOUN
admet-3065	1206	31	:	:	PUNCT
admet-3065	1206	32	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	1206	33	31	31	NUM
admet-3065	1207	1	[	[	X
admet-3065	1207	2	216	216	NUM
admet-3065	1207	3	]	]	X
admet-3065	1207	4	s.e	s.e	PROPN
admet-3065	1207	5	.	.	PROPN
admet-3065	1207	6	baek	baek	PROPN
admet-3065	1207	7	,	,	PUNCT
admet-3065	1207	8	k.h	k.h	PROPN
admet-3065	1207	9	.	.	PROPN
admet-3065	1207	10	lee	lee	PROPN
admet-3065	1207	11	,	,	PUNCT
admet-3065	1207	12	y.s	y.s	PROPN
admet-3065	1207	13	.	.	PROPN
admet-3065	1207	14	park	park	PROPN
admet-3065	1207	15	,	,	PUNCT
admet-3065	1207	16	d.k	d.k	PROPN
admet-3065	1207	17	.	.	PROPN
admet-3065	1208	1	oh	oh	INTJ
admet-3065	1208	2	,	,	PUNCT
admet-3065	1208	3	s.	s.	PROPN
admet-3065	1208	4	oh	oh	INTJ
admet-3065	1208	5	,	,	PUNCT
admet-3065	1209	1	k.s	k.s	PROPN
admet-3065	1209	2	.	.	PROPN
admet-3065	1209	3	kim	kim	PROPN
admet-3065	1209	4	,	,	PUNCT
admet-3065	1209	5	d.e	d.e	PROPN
admet-3065	1209	6	.	.	PROPN
admet-3065	1209	7	kim	kim	PROPN
admet-3065	1209	8	.	.	PUNCT
admet-3065	1210	1	rna	rna	PROPN
admet-3065	1210	2	aptamer	aptamer	NOUN
admet-3065	1210	3	-	-	PUNCT
admet-3065	1210	4	conjugated	conjugate	VERB
admet-3065	1210	5	liposome	liposome	NOUN
admet-3065	1210	6	as	as	ADP
admet-3065	1210	7	an	an	DET
admet-3065	1210	8	efficient	efficient	ADJ
admet-3065	1210	9	anticancer	anticancer	NOUN
admet-3065	1210	10	drug	drug	NOUN
admet-3065	1210	11	delivery	delivery	NOUN
admet-3065	1210	12	vehicle	vehicle	NOUN
admet-3065	1210	13	targeting	target	VERB
admet-3065	1210	14	cancer	cancer	NOUN
admet-3065	1210	15	cells	cell	NOUN
admet-3065	1210	16	in	in	ADP
admet-3065	1210	17	vivo	vivo	NOUN
admet-3065	1210	18	.	.	PUNCT
admet-3065	1211	1	journal	journal	PROPN
admet-3065	1211	2	of	of	ADP
admet-3065	1211	3	controlled	control	VERB
admet-3065	1211	4	release	release	NOUN
admet-3065	1211	5	196	196	NUM
admet-3065	1211	6	(	(	PUNCT
admet-3065	1211	7	2014	2014	NUM
admet-3065	1211	8	)	)	PUNCT
admet-3065	1211	9	234	234	NUM
admet-3065	1211	10	-	-	SYM
admet-3065	1211	11	242	242	NUM
admet-3065	1211	12	.	.	PUNCT
admet-3065	1212	1	https://doi.org/10.1016/j.jconrel.2014.10.018	https://doi.org/10.1016/j.jconrel.2014.10.018	NOUN
admet-3065	1212	2	[	[	X
admet-3065	1212	3	217	217	NUM
admet-3065	1212	4	]	]	PUNCT
admet-3065	1212	5	d.	d.	PROPN
admet-3065	1212	6	rosenblum	rosenblum	PROPN
admet-3065	1212	7	,	,	PUNCT
admet-3065	1212	8	a.	a.	NOUN
admet-3065	1212	9	gutkin	gutkin	PROPN
admet-3065	1212	10	,	,	PUNCT
admet-3065	1212	11	r.	r.	PROPN
admet-3065	1212	12	kedmi	kedmi	PROPN
admet-3065	1212	13	,	,	PUNCT
admet-3065	1212	14	s.	s.	PROPN
admet-3065	1212	15	ramishetti	ramishetti	PROPN
admet-3065	1212	16	,	,	PUNCT
admet-3065	1212	17	n.	n.	PROPN
admet-3065	1212	18	veiga	veiga	PROPN
admet-3065	1212	19	,	,	PUNCT
admet-3065	1212	20	a.m.	a.m.	PROPN
admet-3065	1213	1	jacobi	jacobi	PROPN
admet-3065	1213	2	,	,	PUNCT
admet-3065	1213	3	m.s	m.s	PROPN
admet-3065	1213	4	.	.	PROPN
admet-3065	1213	5	schubert	schubert	PROPN
admet-3065	1213	6	,	,	PUNCT
admet-3065	1213	7	d.	d.	PROPN
admet-3065	1213	8	friedmannmorvinski	friedmannmorvinski	PROPN
admet-3065	1213	9	,	,	PUNCT
admet-3065	1213	10	z.r	z.r	PROPN
admet-3065	1213	11	.	.	PROPN
admet-3065	1213	12	cohen	cohen	PROPN
admet-3065	1213	13	,	,	PUNCT
admet-3065	1213	14	m.a	m.a	PROPN
admet-3065	1213	15	.	.	PROPN
admet-3065	1213	16	behlke	behlke	PROPN
admet-3065	1213	17	,	,	PUNCT
admet-3065	1213	18	j.	j.	PROPN
admet-3065	1213	19	lieberman	lieberman	PROPN
admet-3065	1213	20	,	,	PUNCT
admet-3065	1213	21	d.	d.	PROPN
admet-3065	1213	22	peer	peer	PROPN
admet-3065	1213	23	.	.	PUNCT
admet-3065	1214	1	crispr	crispr	ADJ
admet-3065	1214	2	-	-	PUNCT
admet-3065	1214	3	cas9	cas9	NOUN
admet-3065	1214	4	genome	genome	NOUN
admet-3065	1214	5	editing	editing	NOUN
admet-3065	1214	6	using	use	VERB
admet-3065	1214	7	targeted	target	VERB
admet-3065	1214	8	lipid	lipid	ADJ
admet-3065	1214	9	nanoparticles	nanoparticle	NOUN
admet-3065	1214	10	for	for	ADP
admet-3065	1214	11	cancer	cancer	NOUN
admet-3065	1214	12	therapy	therapy	NOUN
admet-3065	1214	13	.	.	PUNCT
admet-3065	1215	1	science	science	NOUN
admet-3065	1215	2	advances	advance	VERB
admet-3065	1215	3	6	6	NUM
admet-3065	1215	4	(	(	PUNCT
admet-3065	1215	5	2020	2020	NUM
admet-3065	1215	6	)	)	PUNCT
admet-3065	1215	7	9450	9450	NUM
admet-3065	1215	8	.	.	PUNCT
admet-3065	1216	1	https://doi.org/10.1126/sciadv.abc9450	https://doi.org/10.1126/sciadv.abc9450	PROPN
admet-3065	1216	2	[	[	X
admet-3065	1216	3	218	218	NUM
admet-3065	1216	4	]	]	X
admet-3065	1216	5	w.	w.	PROPN
admet-3065	1216	6	ho	ho	PROPN
admet-3065	1216	7	,	,	PUNCT
admet-3065	1216	8	m.	m.	NOUN
admet-3065	1216	9	gao	gao	PROPN
admet-3065	1216	10	,	,	PUNCT
admet-3065	1216	11	f.	f.	PROPN
admet-3065	1216	12	li	li	PROPN
admet-3065	1216	13	,	,	PUNCT
admet-3065	1216	14	z.	z.	PROPN
admet-3065	1216	15	li	li	PROPN
admet-3065	1216	16	,	,	PUNCT
admet-3065	1216	17	x.q	x.q	PROPN
admet-3065	1216	18	.	.	PROPN
admet-3065	1216	19	zhang	zhang	PROPN
admet-3065	1216	20	,	,	PUNCT
admet-3065	1216	21	x.	x.	PROPN
admet-3065	1216	22	xu	xu	PROPN
admet-3065	1216	23	.	.	PUNCT
admet-3065	1217	1	next	next	ADJ
admet-3065	1217	2	-	-	PUNCT
admet-3065	1217	3	generation	generation	NOUN
admet-3065	1217	4	vaccines	vaccine	NOUN
admet-3065	1217	5	:	:	PUNCT
admet-3065	1217	6	nanoparticle	nanoparticle	NOUN
admet-3065	1217	7	-	-	PUNCT
admet-3065	1217	8	mediated	mediate	VERB
admet-3065	1217	9	dna	dna	NOUN
admet-3065	1217	10	and	and	CCONJ
admet-3065	1217	11	mrna	mrna	PROPN
admet-3065	1217	12	delivery	delivery	NOUN
admet-3065	1217	13	.	.	PUNCT
admet-3065	1218	1	advanced	advanced	ADJ
admet-3065	1218	2	healthcare	healthcare	NOUN
admet-3065	1218	3	materials	material	NOUN
admet-3065	1218	4	10	10	NUM
admet-3065	1218	5	(	(	PUNCT
admet-3065	1218	6	2021	2021	NUM
admet-3065	1218	7	)	)	PUNCT
admet-3065	1218	8	2001812	2001812	NUM
admet-3065	1218	9	.	.	PUNCT
admet-3065	1219	1	https://doi.org/10.1002/adhm.202001812	https://doi.org/10.1002/adhm.202001812	NOUN
admet-3065	1220	1	[	[	X
admet-3065	1220	2	219	219	NUM
admet-3065	1220	3	]	]	SYM
admet-3065	1220	4	c.m	c.m	PROPN
admet-3065	1220	5	.	.	PROPN
admet-3065	1220	6	lamanna	lamanna	PROPN
admet-3065	1220	7	,	,	PUNCT
admet-3065	1220	8	h.	h.	PROPN
admet-3065	1220	9	lusic	lusic	PROPN
admet-3065	1220	10	,	,	PUNCT
admet-3065	1220	11	m.	m.	NOUN
admet-3065	1220	12	camplo	camplo	PROPN
admet-3065	1220	13	,	,	PUNCT
admet-3065	1220	14	t.j	t.j	PROPN
admet-3065	1220	15	.	.	PROPN
admet-3065	1220	16	mcintosh	mcintosh	PROPN
admet-3065	1220	17	,	,	PUNCT
admet-3065	1220	18	p.	p.	PROPN
admet-3065	1220	19	barthélémy	barthélémy	PROPN
admet-3065	1220	20	,	,	PUNCT
admet-3065	1220	21	m.w	m.w	PROPN
admet-3065	1220	22	.	.	PROPN
admet-3065	1220	23	grinstaff	grinstaff	PROPN
admet-3065	1220	24	.	.	PUNCT
admet-3065	1221	1	charge	charge	NOUN
admet-3065	1221	2	-	-	PUNCT
admet-3065	1221	3	reversal	reversal	NOUN
admet-3065	1221	4	lipids	lipid	NOUN
admet-3065	1221	5	,	,	PUNCT
admet-3065	1221	6	peptide	peptide	NOUN
admet-3065	1221	7	-	-	PUNCT
admet-3065	1221	8	based	base	VERB
admet-3065	1221	9	lipids	lipid	NOUN
admet-3065	1221	10	,	,	PUNCT
admet-3065	1221	11	and	and	CCONJ
admet-3065	1221	12	nucleoside	nucleoside	NOUN
admet-3065	1221	13	-	-	PUNCT
admet-3065	1221	14	based	base	VERB
admet-3065	1221	15	lipids	lipid	NOUN
admet-3065	1221	16	for	for	ADP
admet-3065	1221	17	gene	gene	NOUN
admet-3065	1221	18	delivery	delivery	NOUN
admet-3065	1221	19	.	.	PUNCT
admet-3065	1222	1	accounts	account	NOUN
admet-3065	1222	2	of	of	ADP
admet-3065	1222	3	chemical	chemical	ADJ
admet-3065	1222	4	research	research	NOUN
admet-3065	1222	5	45	45	NUM
admet-3065	1222	6	(	(	PUNCT
admet-3065	1222	7	2012	2012	NUM
admet-3065	1222	8	)	)	PUNCT
admet-3065	1222	9	1026	1026	NUM
admet-3065	1222	10	-	-	SYM
admet-3065	1222	11	1038	1038	NUM
admet-3065	1222	12	.	.	PUNCT
admet-3065	1223	1	https://doi.org/10.1021/ar200228y	https://doi.org/10.1021/ar200228y	NOUN
admet-3065	1223	2	[	[	X
admet-3065	1223	3	220	220	NUM
admet-3065	1223	4	]	]	PUNCT
admet-3065	1223	5	p.	p.	NOUN
admet-3065	1223	6	midoux	midoux	NOUN
admet-3065	1223	7	,	,	PUNCT
admet-3065	1223	8	c.	c.	PROPN
admet-3065	1223	9	pichon	pichon	PROPN
admet-3065	1223	10	,	,	PUNCT
admet-3065	1223	11	j.j	j.j	PROPN
admet-3065	1223	12	.	.	PROPN
admet-3065	1223	13	yaouanc	yaouanc	PROPN
admet-3065	1223	14	,	,	PUNCT
admet-3065	1223	15	p.a	p.a	PROPN
admet-3065	1223	16	.	.	PROPN
admet-3065	1223	17	jaffrès	jaffrès	PROPN
admet-3065	1223	18	.	.	PUNCT
admet-3065	1224	1	chemical	chemical	ADJ
admet-3065	1224	2	vectors	vector	NOUN
admet-3065	1224	3	for	for	ADP
admet-3065	1224	4	gene	gene	NOUN
admet-3065	1224	5	delivery	delivery	NOUN
admet-3065	1224	6	:	:	PUNCT
admet-3065	1224	7	a	a	DET
admet-3065	1224	8	current	current	ADJ
admet-3065	1224	9	review	review	NOUN
admet-3065	1224	10	on	on	ADP
admet-3065	1224	11	polymers	polymer	NOUN
admet-3065	1224	12	,	,	PUNCT
admet-3065	1224	13	peptides	peptide	NOUN
admet-3065	1224	14	and	and	CCONJ
admet-3065	1224	15	lipids	lipid	NOUN
admet-3065	1224	16	containing	contain	VERB
admet-3065	1224	17	histidine	histidine	NOUN
admet-3065	1224	18	or	or	CCONJ
admet-3065	1224	19	imidazole	imidazole	NOUN
admet-3065	1224	20	as	as	ADP
admet-3065	1224	21	nucleic	nucleic	ADJ
admet-3065	1224	22	acids	acid	NOUN
admet-3065	1224	23	carriers	carrier	NOUN
admet-3065	1224	24	.	.	PUNCT
admet-3065	1225	1	british	british	ADJ
admet-3065	1225	2	journal	journal	PROPN
admet-3065	1225	3	of	of	ADP
admet-3065	1225	4	pharmacology	pharmacology	NOUN
admet-3065	1225	5	157	157	NUM
admet-3065	1225	6	(	(	PUNCT
admet-3065	1225	7	2009	2009	NUM
admet-3065	1225	8	)	)	PUNCT
admet-3065	1225	9	166	166	NUM
admet-3065	1225	10	-	-	SYM
admet-3065	1225	11	178	178	NUM
admet-3065	1225	12	.	.	PUNCT
admet-3065	1226	1	https://doi.org/10.1111/j.1476-5381.2009.00288.x	https://doi.org/10.1111/j.1476-5381.2009.00288.x	NOUN
admet-3065	1227	1	[	[	X
admet-3065	1227	2	221	221	NUM
admet-3065	1227	3	]	]	PUNCT
admet-3065	1227	4	k.	k.	PROPN
admet-3065	1227	5	kita	kita	PROPN
admet-3065	1227	6	,	,	PUNCT
admet-3065	1227	7	c.	c.	PROPN
admet-3065	1227	8	dittrich	dittrich	PROPN
admet-3065	1227	9	.	.	PUNCT
admet-3065	1228	1	drug	drug	NOUN
admet-3065	1228	2	delivery	delivery	NOUN
admet-3065	1228	3	vehicles	vehicle	NOUN
admet-3065	1228	4	with	with	ADP
admet-3065	1228	5	improved	improved	ADJ
admet-3065	1228	6	encapsulation	encapsulation	NOUN
admet-3065	1228	7	efficiency	efficiency	NOUN
admet-3065	1228	8	:	:	PUNCT
admet-3065	1228	9	taking	take	VERB
admet-3065	1228	10	advantage	advantage	NOUN
admet-3065	1228	11	of	of	ADP
admet-3065	1228	12	specific	specific	ADJ
admet-3065	1228	13	drug	drug	NOUN
admet-3065	1228	14	-	-	PUNCT
admet-3065	1228	15	carrier	carrier	NOUN
admet-3065	1228	16	interactions	interaction	NOUN
admet-3065	1228	17	.	.	PUNCT
admet-3065	1229	1	expert	expert	ADJ
admet-3065	1229	2	opinion	opinion	NOUN
admet-3065	1229	3	on	on	ADP
admet-3065	1229	4	drug	drug	NOUN
admet-3065	1229	5	delivery	delivery	NOUN
admet-3065	1229	6	8	8	NUM
admet-3065	1229	7	(	(	PUNCT
admet-3065	1229	8	2011	2011	NUM
admet-3065	1229	9	)	)	PUNCT
admet-3065	1229	10	329	329	NUM
admet-3065	1229	11	-	-	SYM
admet-3065	1229	12	342	342	NUM
admet-3065	1229	13	.	.	PUNCT
admet-3065	1230	1	https://doi.org/10.1517/17425247.2011.553216	https://doi.org/10.1517/17425247.2011.553216	X
admet-3065	1231	1	[	[	X
admet-3065	1231	2	222	222	NUM
admet-3065	1231	3	]	]	X
admet-3065	1231	4	v.	v.	CCONJ
admet-3065	1231	5	trivedi	trivedi	PROPN
admet-3065	1231	6	,	,	PUNCT
admet-3065	1231	7	c.	c.	PROPN
admet-3065	1231	8	yang	yang	PROPN
admet-3065	1231	9	,	,	PUNCT
admet-3065	1231	10	k.	k.	PROPN
admet-3065	1231	11	klippel	klippel	PROPN
admet-3065	1231	12	,	,	PUNCT
admet-3065	1231	13	o.	o.	PROPN
admet-3065	1231	14	yegorov	yegorov	PROPN
admet-3065	1231	15	,	,	PUNCT
admet-3065	1231	16	c.	c.	PROPN
admet-3065	1231	17	von	von	PROPN
admet-3065	1231	18	roemeling	roemeling	PROPN
admet-3065	1231	19	,	,	PUNCT
admet-3065	1231	20	l.	l.	PROPN
admet-3065	1231	21	hoang	hoang	PROPN
admet-3065	1231	22	-	-	PUNCT
admet-3065	1231	23	minh	minh	PROPN
admet-3065	1231	24	,	,	PUNCT
admet-3065	1231	25	g.	g.	PROPN
admet-3065	1231	26	fenton	fenton	PROPN
admet-3065	1231	27	,	,	PUNCT
admet-3065	1231	28	e.	e.	PROPN
admet-3065	1231	29	ogandorivas	ogandorivas	PROPN
admet-3065	1231	30	,	,	PUNCT
admet-3065	1231	31	p.	p.	PROPN
admet-3065	1231	32	castillo	castillo	PROPN
admet-3065	1231	33	,	,	PUNCT
admet-3065	1231	34	g.	g.	PROPN
admet-3065	1231	35	moore	moore	PROPN
admet-3065	1231	36	,	,	PUNCT
admet-3065	1231	37	k.	k.	PROPN
admet-3065	1231	38	long	long	PROPN
admet-3065	1231	39	-	-	PUNCT
admet-3065	1231	40	james	james	PROPN
admet-3065	1231	41	,	,	PUNCT
admet-3065	1231	42	k.	k.	PROPN
admet-3065	1231	43	dyson	dyson	PROPN
admet-3065	1231	44	,	,	PUNCT
admet-3065	1231	45	b.	b.	PROPN
admet-3065	1231	46	doonan	doonan	PROPN
admet-3065	1231	47	,	,	PUNCT
admet-3065	1231	48	c.	c.	PROPN
admet-3065	1231	49	flores	flores	PROPN
admet-3065	1231	50	,	,	PUNCT
admet-3065	1231	51	d.a	d.a	PROPN
admet-3065	1231	52	.	.	PROPN
admet-3065	1231	53	mitchell	mitchell	PROPN
admet-3065	1231	54	.	.	PUNCT
admet-3065	1232	1	mrna	mrna	PROPN
admet-3065	1232	2	-	-	PUNCT
admet-3065	1232	3	based	base	VERB
admet-3065	1232	4	precision	precision	NOUN
admet-3065	1232	5	targeting	targeting	NOUN
admet-3065	1232	6	of	of	ADP
admet-3065	1232	7	neoantigens	neoantigen	NOUN
admet-3065	1232	8	and	and	CCONJ
admet-3065	1232	9	tumor	tumor	NOUN
admet-3065	1232	10	-	-	PUNCT
admet-3065	1232	11	associated	associate	VERB
admet-3065	1232	12	antigens	antigen	NOUN
admet-3065	1232	13	in	in	ADP
admet-3065	1232	14	malignant	malignant	ADJ
admet-3065	1232	15	brain	brain	NOUN
admet-3065	1232	16	tumors	tumor	NOUN
admet-3065	1232	17	.	.	PUNCT
admet-3065	1233	1	genome	genome	NOUN
admet-3065	1233	2	medicine	medicine	NOUN
admet-3065	1233	3	16	16	NUM
admet-3065	1233	4	(	(	PUNCT
admet-3065	1233	5	2024	2024	NUM
admet-3065	1233	6	)	)	PUNCT
admet-3065	1233	7	17	17	NUM
admet-3065	1233	8	.	.	PUNCT
admet-3065	1234	1	https://doi.org/10.1186/s13073-024-01281-z	https://doi.org/10.1186/s13073-024-01281-z	PROPN
admet-3065	1235	1	[	[	X
admet-3065	1235	2	223	223	NUM
admet-3065	1235	3	]	]	PUNCT
admet-3065	1235	4	c.	c.	PROPN
admet-3065	1235	5	chakraborty	chakraborty	PROPN
admet-3065	1235	6	,	,	PUNCT
admet-3065	1235	7	a.r	a.r	PROPN
admet-3065	1235	8	.	.	PROPN
admet-3065	1235	9	sharma	sharma	PROPN
admet-3065	1235	10	,	,	PUNCT
admet-3065	1235	11	m.	m.	PROPN
admet-3065	1235	12	bhattacharya	bhattacharya	PROPN
admet-3065	1235	13	,	,	PUNCT
admet-3065	1235	14	s.s	s.s	PROPN
admet-3065	1235	15	.	.	PROPN
admet-3065	1235	16	lee	lee	PROPN
admet-3065	1235	17	.	.	PROPN
admet-3065	1236	1	from	from	ADP
admet-3065	1236	2	covid-19	covid-19	PROPN
admet-3065	1236	3	to	to	ADP
admet-3065	1236	4	cancer	cancer	NOUN
admet-3065	1236	5	mrna	mrna	PROPN
admet-3065	1236	6	vaccines	vaccine	NOUN
admet-3065	1236	7	:	:	PUNCT
admet-3065	1236	8	moving	move	VERB
admet-3065	1236	9	from	from	ADP
admet-3065	1236	10	bench	bench	NOUN
admet-3065	1236	11	to	to	ADP
admet-3065	1236	12	clinic	clinic	NOUN
admet-3065	1236	13	in	in	ADP
admet-3065	1236	14	the	the	DET
admet-3065	1236	15	vaccine	vaccine	NOUN
admet-3065	1236	16	landscape	landscape	NOUN
admet-3065	1236	17	.	.	PUNCT
admet-3065	1237	1	frontiers	frontier	NOUN
admet-3065	1237	2	in	in	ADP
admet-3065	1237	3	immunology	immunology	NOUN
admet-3065	1237	4	12	12	NUM
admet-3065	1237	5	(	(	PUNCT
admet-3065	1237	6	2021	2021	NUM
admet-3065	1237	7	)	)	PUNCT
admet-3065	1237	8	679344	679344	NUM
admet-3065	1237	9	.	.	PUNCT
admet-3065	1238	1	https://doi.org/10.3389/fimmu.2021.679344	https://doi.org/10.3389/fimmu.2021.679344	PROPN
admet-3065	1238	2	[	[	X
admet-3065	1238	3	224	224	NUM
admet-3065	1238	4	]	]	PUNCT
admet-3065	1238	5	m.	m.	NOUN
admet-3065	1238	6	ronemus	ronemus	PROPN
admet-3065	1238	7	,	,	PUNCT
admet-3065	1238	8	m.w	m.w	PROPN
admet-3065	1238	9	.	.	PROPN
admet-3065	1238	10	vaughn	vaughn	PROPN
admet-3065	1238	11	,	,	PUNCT
admet-3065	1238	12	r.a	r.a	PROPN
admet-3065	1238	13	.	.	PROPN
admet-3065	1238	14	martienssen	martienssen	PROPN
admet-3065	1238	15	.	.	PUNCT
admet-3065	1239	1	microrna	microrna	PROPN
admet-3065	1239	2	-	-	PUNCT
admet-3065	1239	3	targeted	target	VERB
admet-3065	1239	4	and	and	CCONJ
admet-3065	1239	5	small	small	ADJ
admet-3065	1239	6	interfering	interfere	VERB
admet-3065	1239	7	rnamediated	rnamediate	VERB
admet-3065	1239	8	mrna	mrna	NOUN
admet-3065	1239	9	degradation	degradation	NOUN
admet-3065	1239	10	is	be	AUX
admet-3065	1239	11	regulated	regulate	VERB
admet-3065	1239	12	by	by	ADP
admet-3065	1239	13	argonaute	argonaute	PROPN
admet-3065	1239	14	,	,	PUNCT
admet-3065	1239	15	dicer	dicer	NOUN
admet-3065	1239	16	,	,	PUNCT
admet-3065	1239	17	and	and	CCONJ
admet-3065	1239	18	rna	rna	NOUN
admet-3065	1239	19	-	-	PUNCT
admet-3065	1239	20	dependent	dependent	ADJ
admet-3065	1239	21	rna	rna	NOUN
admet-3065	1239	22	polymerase	polymerase	NOUN
admet-3065	1239	23	in	in	ADP
admet-3065	1239	24	arabidopsis	arabidopsis	NOUN
admet-3065	1239	25	.	.	PUNCT
admet-3065	1240	1	the	the	DET
admet-3065	1240	2	plant	plant	NOUN
admet-3065	1240	3	cell	cell	NOUN
admet-3065	1240	4	18	18	NUM
admet-3065	1240	5	(	(	PUNCT
admet-3065	1240	6	2006	2006	NUM
admet-3065	1240	7	)	)	PUNCT
admet-3065	1240	8	1559	1559	NUM
admet-3065	1240	9	-	-	SYM
admet-3065	1240	10	1574	1574	NUM
admet-3065	1240	11	.	.	PUNCT
admet-3065	1241	1	https://doi.org/10.1105/tpc.106.042127	https://doi.org/10.1105/tpc.106.042127	NOUN
admet-3065	1242	1	[	[	X
admet-3065	1242	2	225	225	NUM
admet-3065	1242	3	]	]	X
admet-3065	1242	4	l.	l.	PROPN
admet-3065	1242	5	aagaard	aagaard	PROPN
admet-3065	1242	6	,	,	PUNCT
admet-3065	1242	7	j.j	j.j	PROPN
admet-3065	1242	8	.	.	PROPN
admet-3065	1242	9	rossi	rossi	PROPN
admet-3065	1242	10	.	.	PUNCT
admet-3065	1243	1	rnai	rnai	PROPN
admet-3065	1243	2	therapeutics	therapeutic	NOUN
admet-3065	1243	3	:	:	PUNCT
admet-3065	1243	4	principles	principle	NOUN
admet-3065	1243	5	,	,	PUNCT
admet-3065	1243	6	prospects	prospect	NOUN
admet-3065	1243	7	and	and	CCONJ
admet-3065	1243	8	challenges	challenge	NOUN
admet-3065	1243	9	.	.	PUNCT
admet-3065	1244	1	advanced	advanced	ADJ
admet-3065	1244	2	drug	drug	NOUN
admet-3065	1244	3	delivery	delivery	NOUN
admet-3065	1244	4	reviews	review	VERB
admet-3065	1244	5	59	59	NUM
admet-3065	1244	6	(	(	PUNCT
admet-3065	1244	7	2007	2007	NUM
admet-3065	1244	8	)	)	PUNCT
admet-3065	1244	9	75	75	NUM
admet-3065	1244	10	-	-	SYM
admet-3065	1244	11	86	86	NUM
admet-3065	1244	12	.	.	PUNCT
admet-3065	1245	1	https://doi.org/10.1016/j.addr.2007.03.005	https://doi.org/10.1016/j.addr.2007.03.005	PROPN
admet-3065	1245	2	[	[	X
admet-3065	1245	3	226	226	NUM
admet-3065	1245	4	]	]	X
admet-3065	1245	5	j.k.w	j.k.w	NOUN
admet-3065	1245	6	.	.	PUNCT
admet-3065	1246	1	lam	lam	PROPN
admet-3065	1246	2	,	,	PUNCT
admet-3065	1246	3	m.y.t	m.y.t	X
admet-3065	1246	4	.	.	PUNCT
admet-3065	1247	1	chow	chow	PROPN
admet-3065	1247	2	,	,	PUNCT
admet-3065	1247	3	y.	y.	PROPN
admet-3065	1247	4	zhang	zhang	PROPN
admet-3065	1247	5	,	,	PUNCT
admet-3065	1247	6	s.w.s	s.w.s	PROPN
admet-3065	1247	7	.	.	PUNCT
admet-3065	1247	8	leung	leung	PROPN
admet-3065	1247	9	.	.	PUNCT
admet-3065	1248	1	sirna	sirna	PROPN
admet-3065	1248	2	versus	versus	ADP
admet-3065	1248	3	mirna	mirna	PROPN
admet-3065	1248	4	as	as	ADP
admet-3065	1248	5	therapeutics	therapeutic	NOUN
admet-3065	1248	6	for	for	ADP
admet-3065	1248	7	gene	gene	NOUN
admet-3065	1248	8	silencing	silence	VERB
admet-3065	1248	9	.	.	PUNCT
admet-3065	1249	1	molecular	molecular	ADJ
admet-3065	1249	2	therapy	therapy	NOUN
admet-3065	1249	3	nucleic	nucleic	ADJ
admet-3065	1249	4	acids	acid	NOUN
admet-3065	1249	5	4	4	NUM
admet-3065	1249	6	(	(	PUNCT
admet-3065	1249	7	2015	2015	NUM
admet-3065	1249	8	)	)	PUNCT
admet-3065	1249	9	252	252	NUM
admet-3065	1249	10	.	.	PUNCT
admet-3065	1250	1	https://doi.org/10.1038/mtna.2015.23	https://doi.org/10.1038/mtna.2015.23	PROPN
admet-3065	1250	2	.	.	PUNCT
admet-3065	1251	1	[	[	X
admet-3065	1251	2	227	227	NUM
admet-3065	1251	3	]	]	X
admet-3065	1251	4	h.	h.	PROPN
admet-3065	1251	5	isazadeh	isazadeh	PROPN
admet-3065	1251	6	,	,	PUNCT
admet-3065	1251	7	f.	f.	PROPN
admet-3065	1251	8	oruji	oruji	PROPN
admet-3065	1251	9	,	,	PUNCT
admet-3065	1251	10	s.	s.	PROPN
admet-3065	1251	11	shabani	shabani	PROPN
admet-3065	1251	12	,	,	PUNCT
admet-3065	1251	13	j.	j.	PROPN
admet-3065	1251	14	behroozi	behroozi	PROPN
admet-3065	1251	15	,	,	PUNCT
admet-3065	1251	16	h.	h.	PROPN
admet-3065	1251	17	nasiri	nasiri	ADV
admet-3065	1251	18	,	,	PUNCT
admet-3065	1251	19	a.	a.	NOUN
admet-3065	1251	20	isazadeh	isazadeh	PROPN
admet-3065	1251	21	,	,	PUNCT
admet-3065	1251	22	m.	m.	NOUN
admet-3065	1251	23	akbari	akbari	PROPN
admet-3065	1251	24	.	.	PUNCT
admet-3065	1252	1	advances	advance	NOUN
admet-3065	1252	2	in	in	ADP
admet-3065	1252	3	sirna	sirna	PROPN
admet-3065	1252	4	delivery	delivery	PROPN
admet-3065	1252	5	approaches	approach	VERB
admet-3065	1252	6	in	in	ADP
admet-3065	1252	7	cancer	cancer	NOUN
admet-3065	1252	8	therapy	therapy	NOUN
admet-3065	1252	9	:	:	PUNCT
admet-3065	1252	10	challenges	challenge	NOUN
admet-3065	1252	11	and	and	CCONJ
admet-3065	1252	12	opportunities	opportunity	NOUN
admet-3065	1252	13	.	.	PUNCT
admet-3065	1253	1	molecular	molecular	ADJ
admet-3065	1253	2	biology	biology	NOUN
admet-3065	1253	3	reports	report	VERB
admet-3065	1253	4	50	50	NUM
admet-3065	1253	5	(	(	PUNCT
admet-3065	1253	6	2023	2023	NUM
admet-3065	1253	7	)	)	PUNCT
admet-3065	1253	8	9529	9529	NUM
admet-3065	1253	9	-	-	SYM
admet-3065	1253	10	9543	9543	NUM
admet-3065	1253	11	.	.	PUNCT
admet-3065	1254	1	https://doi.org/10.1007/s11033-023-08749-y	https://doi.org/10.1007/s11033-023-08749-y	PROPN
admet-3065	1254	2	[	[	X
admet-3065	1254	3	228	228	NUM
admet-3065	1254	4	]	]	X
admet-3065	1254	5	p.r	p.r	PROPN
admet-3065	1254	6	.	.	PROPN
admet-3065	1254	7	cullis	cullis	PROPN
admet-3065	1254	8	,	,	PUNCT
admet-3065	1254	9	m.j	m.j	PROPN
admet-3065	1254	10	.	.	PROPN
admet-3065	1254	11	hope	hope	PROPN
admet-3065	1254	12	.	.	PUNCT
admet-3065	1255	1	lipid	lipid	PROPN
admet-3065	1255	2	nanoparticle	nanoparticle	NOUN
admet-3065	1255	3	systems	system	NOUN
admet-3065	1255	4	for	for	ADP
admet-3065	1255	5	enabling	enable	VERB
admet-3065	1255	6	gene	gene	NOUN
admet-3065	1255	7	therapies	therapy	NOUN
admet-3065	1255	8	.	.	PUNCT
admet-3065	1256	1	molecular	molecular	ADJ
admet-3065	1256	2	therapy	therapy	NOUN
admet-3065	1256	3	25	25	NUM
admet-3065	1256	4	(	(	PUNCT
admet-3065	1256	5	2017	2017	NUM
admet-3065	1256	6	)	)	PUNCT
admet-3065	1256	7	1467	1467	NUM
admet-3065	1256	8	-	-	SYM
admet-3065	1256	9	1475	1475	NUM
admet-3065	1256	10	.	.	PUNCT
admet-3065	1257	1	https://doi.org/10.1016/j.ymthe.2017.03.013	https://doi.org/10.1016/j.ymthe.2017.03.013	VERB
admet-3065	1257	2	[	[	PUNCT
admet-3065	1257	3	229	229	NUM
admet-3065	1257	4	]	]	X
admet-3065	1257	5	j.a	j.a	PROPN
admet-3065	1257	6	.	.	PROPN
admet-3065	1257	7	kulkarni	kulkarni	PROPN
admet-3065	1257	8	,	,	PUNCT
admet-3065	1257	9	d.	d.	PROPN
admet-3065	1257	10	witzigmann	witzigmann	PROPN
admet-3065	1257	11	,	,	PUNCT
admet-3065	1257	12	s.	s.	PROPN
admet-3065	1257	13	chen	chen	PROPN
admet-3065	1257	14	,	,	PUNCT
admet-3065	1257	15	p.r	p.r	PROPN
admet-3065	1257	16	.	.	PROPN
admet-3065	1257	17	cullis	cullis	PROPN
admet-3065	1257	18	,	,	PUNCT
admet-3065	1257	19	r.	r.	PROPN
admet-3065	1257	20	van	van	PROPN
admet-3065	1257	21	der	der	PROPN
admet-3065	1257	22	meel	meel	PROPN
admet-3065	1257	23	.	.	PUNCT
admet-3065	1258	1	lipid	lipid	PROPN
admet-3065	1258	2	nanoparticle	nanoparticle	NOUN
admet-3065	1258	3	technology	technology	NOUN
admet-3065	1258	4	for	for	ADP
admet-3065	1258	5	clinical	clinical	ADJ
admet-3065	1258	6	translation	translation	NOUN
admet-3065	1258	7	of	of	ADP
admet-3065	1258	8	sirna	sirna	PROPN
admet-3065	1258	9	therapeutics	therapeutic	NOUN
admet-3065	1258	10	.	.	PUNCT
admet-3065	1259	1	accounts	account	NOUN
admet-3065	1259	2	of	of	ADP
admet-3065	1259	3	chemical	chemical	ADJ
admet-3065	1259	4	research	research	NOUN
admet-3065	1259	5	52	52	NUM
admet-3065	1259	6	(	(	PUNCT
admet-3065	1259	7	2019	2019	NUM
admet-3065	1259	8	)	)	PUNCT
admet-3065	1259	9	2435	2435	NUM
admet-3065	1259	10	-	-	SYM
admet-3065	1259	11	2444	2444	NUM
admet-3065	1259	12	.	.	PUNCT
admet-3065	1260	1	https://doi.org/10.1021/acs.accounts.9b00368	https://doi.org/10.1021/acs.accounts.9b00368	VERB
admet-3065	1260	2	[	[	X
admet-3065	1260	3	230	230	NUM
admet-3065	1260	4	]	]	PUNCT
admet-3065	1260	5	l.	l.	PROPN
admet-3065	1260	6	han	han	PROPN
admet-3065	1260	7	,	,	PUNCT
admet-3065	1260	8	c.	c.	PROPN
admet-3065	1260	9	tang	tang	PROPN
admet-3065	1260	10	,	,	PUNCT
admet-3065	1260	11	c.	c.	PROPN
admet-3065	1260	12	yin	yin	PROPN
admet-3065	1260	13	.	.	PUNCT
admet-3065	1261	1	oral	oral	ADJ
admet-3065	1261	2	delivery	delivery	NOUN
admet-3065	1261	3	of	of	ADP
admet-3065	1261	4	shrna	shrna	NOUN
admet-3065	1261	5	and	and	CCONJ
admet-3065	1261	6	sirna	sirna	PROPN
admet-3065	1261	7	via	via	ADP
admet-3065	1261	8	multifunctional	multifunctional	ADJ
admet-3065	1261	9	polymeric	polymeric	ADJ
admet-3065	1261	10	nanoparticles	nanoparticle	NOUN
admet-3065	1261	11	for	for	ADP
admet-3065	1261	12	synergistic	synergistic	ADJ
admet-3065	1261	13	cancer	cancer	NOUN
admet-3065	1261	14	therapy	therapy	NOUN
admet-3065	1261	15	.	.	PUNCT
admet-3065	1262	1	biomaterials	biomaterial	NOUN
admet-3065	1262	2	35	35	NUM
admet-3065	1262	3	(	(	PUNCT
admet-3065	1262	4	2014	2014	NUM
admet-3065	1262	5	)	)	PUNCT
admet-3065	1262	6	4589	4589	NUM
admet-3065	1262	7	-	-	SYM
admet-3065	1262	8	4600	4600	NUM
admet-3065	1262	9	.	.	PUNCT
admet-3065	1263	1	https://doi.org/10.1016/j.biomaterials.2014.02.027	https://doi.org/10.1016/j.biomaterials.2014.02.027	NUM
admet-3065	1264	1	[	[	X
admet-3065	1264	2	231	231	NUM
admet-3065	1264	3	]	]	PUNCT
admet-3065	1264	4	d.	d.	PROPN
admet-3065	1264	5	oliver	oliver	PROPN
admet-3065	1264	6	,	,	PUNCT
admet-3065	1264	7	h.	h.	PROPN
admet-3065	1264	8	ji	ji	PROPN
admet-3065	1264	9	,	,	PUNCT
admet-3065	1264	10	p.	p.	PROPN
admet-3065	1264	11	liu	liu	PROPN
admet-3065	1264	12	,	,	PUNCT
admet-3065	1264	13	a.	a.	NOUN
admet-3065	1264	14	gasparian	gasparian	PROPN
admet-3065	1264	15	,	,	PUNCT
admet-3065	1264	16	e.	e.	PROPN
admet-3065	1264	17	gardiner	gardiner	PROPN
admet-3065	1264	18	,	,	PUNCT
admet-3065	1264	19	s.	s.	PROPN
admet-3065	1264	20	lee	lee	PROPN
admet-3065	1264	21	,	,	PUNCT
admet-3065	1264	22	a.	a.	PROPN
admet-3065	1264	23	zenteno	zenteno	PROPN
admet-3065	1264	24	,	,	PUNCT
admet-3065	1264	25	l.o	l.o	PROPN
admet-3065	1264	26	.	.	PROPN
admet-3065	1264	27	perinskaya	perinskaya	PROPN
admet-3065	1264	28	,	,	PUNCT
admet-3065	1264	29	m.	m.	NOUN
admet-3065	1264	30	chen	chen	PROPN
admet-3065	1264	31	,	,	PUNCT
admet-3065	1264	32	p.	p.	PROPN
admet-3065	1264	33	buckhaults	buckhaults	PROPN
admet-3065	1264	34	,	,	PUNCT
admet-3065	1264	35	e.	e.	PROPN
admet-3065	1264	36	broude	broude	PROPN
admet-3065	1264	37	,	,	PUNCT
admet-3065	1264	38	m.d	m.d	PROPN
admet-3065	1264	39	.	.	PROPN
admet-3065	1264	40	wyatt	wyatt	PROPN
admet-3065	1264	41	,	,	PUNCT
admet-3065	1264	42	h.	h.	PROPN
admet-3065	1264	43	valafar	valafar	PROPN
admet-3065	1264	44	,	,	PUNCT
admet-3065	1264	45	e.	e.	PROPN
admet-3065	1264	46	peña	peña	PROPN
admet-3065	1264	47	,	,	PUNCT
admet-3065	1264	48	m.	m.	NOUN
admet-3065	1264	49	shtutman	shtutman	NOUN
admet-3065	1264	50	.	.	PUNCT
admet-3065	1265	1	identification	identification	NOUN
admet-3065	1265	2	of	of	ADP
admet-3065	1265	3	novel	novel	ADJ
admet-3065	1265	4	cancer	cancer	NOUN
admet-3065	1265	5	therapeutic	therapeutic	ADJ
admet-3065	1265	6	targets	target	NOUN
admet-3065	1265	7	using	use	VERB
admet-3065	1265	8	a	a	DET
admet-3065	1265	9	designed	design	VERB
admet-3065	1265	10	and	and	CCONJ
admet-3065	1265	11	pooled	pool	VERB
admet-3065	1265	12	shrna	shrna	ADJ
admet-3065	1265	13	library	library	NOUN
admet-3065	1265	14	screen	screen	NOUN
admet-3065	1265	15	.	.	PUNCT
admet-3065	1266	1	scientific	scientific	ADJ
admet-3065	1266	2	reports	report	NOUN
admet-3065	1266	3	7	7	NUM
admet-3065	1266	4	(	(	PUNCT
admet-3065	1266	5	2017	2017	NUM
admet-3065	1266	6	)	)	PUNCT
admet-3065	1266	7	43023	43023	NUM
admet-3065	1266	8	.	.	PUNCT
admet-3065	1267	1	https://doi.org/10.1038/srep43023	https://doi.org/10.1038/srep43023	PROPN
admet-3065	1267	2	https://doi.org/10.1016/j.jconrel.2014.10.018	https://doi.org/10.1016/j.jconrel.2014.10.018	NOUN
admet-3065	1267	3	https://doi.org/10.1126/sciadv.abc9450	https://doi.org/10.1126/sciadv.abc9450	ADJ
admet-3065	1267	4	https://doi.org/10.1002/adhm.202001812	https://doi.org/10.1002/adhm.202001812	NOUN
admet-3065	1267	5	https://doi.org/10.1021/ar200228y	https://doi.org/10.1021/ar200228y	NOUN
admet-3065	1267	6	https://doi.org/10.1111/j.1476-5381.2009.00288.x	https://doi.org/10.1111/j.1476-5381.2009.00288.x	NOUN
admet-3065	1267	7	https://doi.org/10.1517/17425247.2011.553216	https://doi.org/10.1517/17425247.2011.553216	X
admet-3065	1267	8	https://doi.org/10.1186/s13073-024-01281-z	https://doi.org/10.1186/s13073-024-01281-z	PROPN
admet-3065	1267	9	https://doi.org/10.3389/fimmu.2021.679344	https://doi.org/10.3389/fimmu.2021.679344	PROPN
admet-3065	1267	10	https://doi.org/10.1105/tpc.106.042127	https://doi.org/10.1105/tpc.106.042127	NOUN
admet-3065	1267	11	https://doi.org/10.1016/j.addr.2007.03.005	https://doi.org/10.1016/j.addr.2007.03.005	NOUN
admet-3065	1267	12	https://doi.org/10.1038/mtna.2015.23	https://doi.org/10.1038/mtna.2015.23	PROPN
admet-3065	1267	13	https://doi.org/10.1007/s11033-023-08749-y	https://doi.org/10.1007/s11033-023-08749-y	PROPN
admet-3065	1267	14	https://doi.org/10.1016/j.ymthe.2017.03.013	https://doi.org/10.1016/j.ymthe.2017.03.013	PROPN
admet-3065	1267	15	https://doi.org/10.1021/acs.accounts.9b00368	https://doi.org/10.1021/acs.accounts.9b00368	PROPN
admet-3065	1267	16	https://doi.org/10.1016/j.biomaterials.2014.02.027	https://doi.org/10.1016/j.biomaterials.2014.02.027	PROPN
admet-3065	1267	17	https://doi.org/10.1038/srep43023	https://doi.org/10.1038/srep43023	PROPN
admet-3065	1267	18	e.	e.	PROPN
admet-3065	1267	19	j.	j.	PROPN
admet-3065	1267	20	saleh	saleh	PROPN
admet-3065	1267	21	et	et	PROPN
admet-3065	1267	22	al	al	PROPN
admet-3065	1267	23	.	.	PROPN
admet-3065	1267	24	admet	admet	PROPN
admet-3065	1267	25	&	&	CCONJ
admet-3065	1267	26	dmpk	dmpk	PROPN
admet-3065	1267	27	00(0	00(0	PROPN
admet-3065	1267	28	)	)	PUNCT
admet-3065	1267	29	(	(	PUNCT
admet-3065	1267	30	2025	2025	NUM
admet-3065	1267	31	)	)	PUNCT
admet-3065	1267	32	3065	3065	NUM
admet-3065	1267	33	32	32	NUM
admet-3065	1268	1	[	[	X
admet-3065	1268	2	232	232	NUM
admet-3065	1268	3	]	]	X
admet-3065	1268	4	c.b	c.b	PROPN
admet-3065	1268	5	.	.	PROPN
admet-3065	1268	6	moore	moore	PROPN
admet-3065	1268	7	,	,	PUNCT
admet-3065	1268	8	e.h	e.h	PROPN
admet-3065	1268	9	.	.	PROPN
admet-3065	1268	10	guthrie	guthrie	PROPN
admet-3065	1268	11	,	,	PUNCT
admet-3065	1268	12	m.t.h	m.t.h	PROPN
admet-3065	1268	13	.	.	PUNCT
admet-3065	1269	1	huang	huang	PROPN
admet-3065	1269	2	,	,	PUNCT
admet-3065	1269	3	d.j	d.j	PROPN
admet-3065	1269	4	.	.	PROPN
admet-3065	1269	5	taxman	taxman	NOUN
admet-3065	1269	6	.	.	PUNCT
admet-3065	1270	1	short	short	ADJ
admet-3065	1270	2	hairpin	hairpin	ADJ
admet-3065	1270	3	rna	rna	NOUN
admet-3065	1270	4	(	(	PUNCT
admet-3065	1270	5	shrna	shrna	NOUN
admet-3065	1270	6	):	):	PUNCT
admet-3065	1270	7	design	design	NOUN
admet-3065	1270	8	,	,	PUNCT
admet-3065	1270	9	delivery	delivery	NOUN
admet-3065	1270	10	,	,	PUNCT
admet-3065	1270	11	and	and	CCONJ
admet-3065	1270	12	assessment	assessment	NOUN
admet-3065	1270	13	of	of	ADP
admet-3065	1270	14	gene	gene	NOUN
admet-3065	1270	15	knockdown	knockdown	NOUN
admet-3065	1270	16	.	.	PUNCT
admet-3065	1271	1	methods	method	NOUN
admet-3065	1271	2	in	in	ADP
admet-3065	1271	3	molecular	molecular	ADJ
admet-3065	1271	4	biology	biology	NOUN
admet-3065	1271	5	629	629	NUM
admet-3065	1271	6	(	(	PUNCT
admet-3065	1271	7	2010	2010	NUM
admet-3065	1271	8	)	)	PUNCT
admet-3065	1271	9	141	141	NUM
admet-3065	1271	10	-	-	SYM
admet-3065	1271	11	158	158	NUM
admet-3065	1271	12	.	.	PUNCT
admet-3065	1272	1	https://doi.org/10.1007/978-1-60761-657-3_10	https://doi.org/10.1007/978-1-60761-657-3_10	VERB
admet-3065	1272	2	[	[	PUNCT
admet-3065	1272	3	233	233	NUM
admet-3065	1272	4	]	]	X
admet-3065	1272	5	b.l	b.l	PROPN
admet-3065	1272	6	.	.	PROPN
admet-3065	1272	7	davidson	davidson	PROPN
admet-3065	1272	8	,	,	PUNCT
admet-3065	1272	9	s.q	s.q	PROPN
admet-3065	1272	10	.	.	PROPN
admet-3065	1272	11	harper	harper	PROPN
admet-3065	1272	12	.	.	PUNCT
admet-3065	1273	1	viral	viral	ADJ
admet-3065	1273	2	delivery	delivery	NOUN
admet-3065	1273	3	of	of	ADP
admet-3065	1273	4	recombinant	recombinant	ADJ
admet-3065	1273	5	short	short	ADJ
admet-3065	1273	6	hairpin	hairpin	NOUN
admet-3065	1273	7	ras	ra	NOUN
admet-3065	1273	8	.	.	PUNCT
admet-3065	1273	9	methods	method	NOUN
admet-3065	1273	10	in	in	ADP
admet-3065	1273	11	enzymology	enzymology	NOUN
admet-3065	1273	12	392	392	NUM
admet-3065	1273	13	(	(	PUNCT
admet-3065	1273	14	2005	2005	NUM
admet-3065	1273	15	)	)	PUNCT
admet-3065	1273	16	145	145	NUM
admet-3065	1273	17	-	-	SYM
admet-3065	1273	18	173	173	NUM
admet-3065	1273	19	.	.	PUNCT
admet-3065	1274	1	https://doi.org/10.1016/s0076-6879(04)92009-5	https://doi.org/10.1016/s0076-6879(04)92009-5	X
admet-3065	1275	1	[	[	X
admet-3065	1275	2	234	234	NUM
admet-3065	1275	3	]	]	X
admet-3065	1275	4	c.a	c.a	PROPN
admet-3065	1275	5	.	.	PROPN
admet-3065	1275	6	helliwell	helliwell	PROPN
admet-3065	1275	7	,	,	PUNCT
admet-3065	1275	8	p.m.	p.m.	NOUN
admet-3065	1275	9	waterhouse	waterhouse	PROPN
admet-3065	1275	10	.	.	PUNCT
admet-3065	1276	1	constructs	construct	NOUN
admet-3065	1276	2	and	and	CCONJ
admet-3065	1276	3	methods	method	NOUN
admet-3065	1276	4	for	for	ADP
admet-3065	1276	5	hairpin	hairpin	VERB
admet-3065	1276	6	rna	rna	NOUN
admet-3065	1276	7	-	-	PUNCT
admet-3065	1276	8	mediated	mediate	VERB
admet-3065	1276	9	gene	gene	NOUN
admet-3065	1276	10	silencing	silence	VERB
admet-3065	1276	11	in	in	ADP
admet-3065	1276	12	plants	plant	NOUN
admet-3065	1276	13	.	.	PUNCT
admet-3065	1277	1	methods	method	NOUN
admet-3065	1277	2	in	in	ADP
admet-3065	1277	3	enzymology	enzymology	NOUN
admet-3065	1277	4	392	392	NUM
admet-3065	1277	5	(	(	PUNCT
admet-3065	1277	6	2005	2005	NUM
admet-3065	1277	7	)	)	PUNCT
admet-3065	1277	8	24	24	NUM
admet-3065	1277	9	-	-	SYM
admet-3065	1277	10	35	35	NUM
admet-3065	1277	11	.	.	PUNCT
admet-3065	1278	1	https://doi.org/10.1016/s0076-6879(04)92002-2	https://doi.org/10.1016/s0076-6879(04)92002-2	NOUN
admet-3065	1279	1	[	[	X
admet-3065	1279	2	235	235	NUM
admet-3065	1279	3	]	]	X
admet-3065	1279	4	s.v	s.v	PROPN
admet-3065	1279	5	.	.	PROPN
admet-3065	1279	6	wesley	wesley	PROPN
admet-3065	1279	7	,	,	PUNCT
admet-3065	1279	8	q.	q.	PROPN
admet-3065	1279	9	liu	liu	PROPN
admet-3065	1279	10	,	,	PUNCT
admet-3065	1279	11	a.	a.	NOUN
admet-3065	1279	12	wielopolska	wielopolska	PROPN
admet-3065	1279	13	,	,	PUNCT
admet-3065	1279	14	g.	g.	PROPN
admet-3065	1279	15	ellacott	ellacott	PROPN
admet-3065	1279	16	,	,	PUNCT
admet-3065	1279	17	n.	n.	PROPN
admet-3065	1279	18	smith	smith	PROPN
admet-3065	1279	19	,	,	PUNCT
admet-3065	1279	20	s.	s.	PROPN
admet-3065	1279	21	singh	singh	PROPN
admet-3065	1279	22	,	,	PUNCT
admet-3065	1279	23	c.	c.	PROPN
admet-3065	1279	24	helliwell	helliwell	PROPN
admet-3065	1279	25	.	.	PUNCT
admet-3065	1280	1	custom	custom	NOUN
admet-3065	1280	2	knock	knock	NOUN
admet-3065	1280	3	-	-	PUNCT
admet-3065	1280	4	outs	out	NOUN
admet-3065	1280	5	with	with	ADP
admet-3065	1280	6	hairpin	hairpin	ADJ
admet-3065	1280	7	rna	rna	NOUN
admet-3065	1280	8	-	-	PUNCT
admet-3065	1280	9	mediated	mediate	VERB
admet-3065	1280	10	gene	gene	NOUN
admet-3065	1280	11	silencing	silencing	NOUN
admet-3065	1280	12	.	.	PUNCT
admet-3065	1281	1	methods	method	NOUN
admet-3065	1281	2	in	in	ADP
admet-3065	1281	3	molecular	molecular	ADJ
admet-3065	1281	4	biology	biology	NOUN
admet-3065	1281	5	236	236	NUM
admet-3065	1281	6	(	(	PUNCT
admet-3065	1281	7	2003	2003	NUM
admet-3065	1281	8	)	)	PUNCT
admet-3065	1281	9	273	273	NUM
admet-3065	1281	10	-	-	SYM
admet-3065	1281	11	286	286	NUM
admet-3065	1281	12	.	.	PUNCT
admet-3065	1282	1	https://doi.org/10.1385/1-59259-413-1:273	https://doi.org/10.1385/1-59259-413-1:273	PROPN
admet-3065	1282	2	[	[	X
admet-3065	1282	3	236	236	NUM
admet-3065	1282	4	]	]	X
admet-3065	1282	5	r.a	r.a	PROPN
admet-3065	1282	6	.	.	PROPN
admet-3065	1282	7	shivdasani	shivdasani	PROPN
admet-3065	1282	8	.	.	PUNCT
admet-3065	1283	1	micrornas	microrna	NOUN
admet-3065	1283	2	:	:	PUNCT
admet-3065	1283	3	regulators	regulator	NOUN
admet-3065	1283	4	of	of	ADP
admet-3065	1283	5	gene	gene	NOUN
admet-3065	1283	6	expression	expression	NOUN
admet-3065	1283	7	and	and	CCONJ
admet-3065	1283	8	cell	cell	NOUN
admet-3065	1283	9	differentiation	differentiation	NOUN
admet-3065	1283	10	.	.	PUNCT
admet-3065	1284	1	blood	blood	NOUN
admet-3065	1284	2	108	108	NUM
admet-3065	1284	3	(	(	PUNCT
admet-3065	1284	4	2006	2006	NUM
admet-3065	1284	5	)	)	PUNCT
admet-3065	1284	6	3646	3646	NUM
admet-3065	1284	7	-	-	SYM
admet-3065	1284	8	3653	3653	NUM
admet-3065	1284	9	.	.	PUNCT
admet-3065	1285	1	https://doi.org/10.1182/blood-2006-01-030015	https://doi.org/10.1182/blood-2006-01-030015	PUNCT
admet-3065	1286	1	[	[	X
admet-3065	1286	2	237	237	NUM
admet-3065	1286	3	]	]	PUNCT
admet-3065	1286	4	n.	n.	NOUN
admet-3065	1286	5	lynam	lynam	PROPN
admet-3065	1286	6	-	-	PUNCT
admet-3065	1286	7	lennon	lennon	PROPN
admet-3065	1286	8	,	,	PUNCT
admet-3065	1286	9	s.g	s.g	PROPN
admet-3065	1286	10	.	.	PROPN
admet-3065	1286	11	maher	maher	PROPN
admet-3065	1286	12	,	,	PUNCT
admet-3065	1286	13	j.v	j.v	PROPN
admet-3065	1286	14	.	.	PROPN
admet-3065	1286	15	reynolds	reynolds	PROPN
admet-3065	1286	16	.	.	PUNCT
admet-3065	1287	1	the	the	DET
admet-3065	1287	2	roles	role	NOUN
admet-3065	1287	3	of	of	ADP
admet-3065	1287	4	microrna	microrna	PROPN
admet-3065	1287	5	in	in	ADP
admet-3065	1287	6	cancer	cancer	NOUN
admet-3065	1287	7	and	and	CCONJ
admet-3065	1287	8	apoptosis	apoptosis	NOUN
admet-3065	1287	9	.	.	PUNCT
admet-3065	1288	1	biological	biological	ADJ
admet-3065	1288	2	reviews	review	NOUN
admet-3065	1288	3	84	84	NUM
admet-3065	1288	4	(	(	PUNCT
admet-3065	1288	5	2009	2009	NUM
admet-3065	1288	6	)	)	PUNCT
admet-3065	1288	7	55	55	NUM
admet-3065	1288	8	-	-	SYM
admet-3065	1288	9	71	71	NUM
admet-3065	1288	10	.	.	PUNCT
admet-3065	1288	11	https://doi.org/10.1111/j.1469-185x.2008.00061.x	https://doi.org/10.1111/j.1469-185x.2008.00061.x	PUNCT
admet-3065	1289	1	[	[	X
admet-3065	1289	2	238	238	NUM
admet-3065	1289	3	]	]	X
admet-3065	1289	4	g.	g.	PROPN
admet-3065	1289	5	yang	yang	PROPN
admet-3065	1289	6	,	,	PUNCT
admet-3065	1289	7	b.	b.	PROPN
admet-3065	1289	8	yin	yin	PROPN
admet-3065	1289	9	.	.	PUNCT
admet-3065	1290	1	the	the	DET
admet-3065	1290	2	advance	advance	NOUN
admet-3065	1290	3	of	of	ADP
admet-3065	1290	4	application	application	NOUN
admet-3065	1290	5	for	for	ADP
admet-3065	1290	6	micrornas	microrna	NOUN
admet-3065	1290	7	in	in	ADP
admet-3065	1290	8	cancer	cancer	NOUN
admet-3065	1290	9	gene	gene	NOUN
admet-3065	1290	10	therapy	therapy	NOUN
admet-3065	1290	11	.	.	PUNCT
admet-3065	1291	1	biomedicine	biomedicine	NOUN
admet-3065	1291	2	&	&	CCONJ
admet-3065	1291	3	pharmacotherapy	pharmacotherapy	NOUN
admet-3065	1291	4	8	8	NUM
admet-3065	1291	5	(	(	PUNCT
admet-3065	1291	6	2014	2014	NUM
admet-3065	1291	7	)	)	PUNCT
admet-3065	1291	8	137	137	NUM
admet-3065	1291	9	-	-	SYM
admet-3065	1291	10	142	142	NUM
admet-3065	1291	11	.	.	PUNCT
admet-3065	1292	1	https://doi.org/10.1016/j.biopha.2013.10.002	https://doi.org/10.1016/j.biopha.2013.10.002	VERB
admet-3065	1292	2	[	[	X
admet-3065	1292	3	239	239	NUM
admet-3065	1292	4	]	]	PUNCT
admet-3065	1292	5	m.	m.	NOUN
admet-3065	1292	6	ishida	ishida	PROPN
admet-3065	1292	7	,	,	PUNCT
admet-3065	1292	8	f.m	f.m	PROPN
admet-3065	1292	9	.	.	PROPN
admet-3065	1292	10	selaru	selaru	PROPN
admet-3065	1292	11	.	.	PUNCT
admet-3065	1293	1	mirna	mirna	NOUN
admet-3065	1293	2	-	-	PUNCT
admet-3065	1293	3	based	base	VERB
admet-3065	1293	4	therapeutic	therapeutic	ADJ
admet-3065	1293	5	strategies	strategy	NOUN
admet-3065	1293	6	.	.	PUNCT
admet-3065	1294	1	current	current	ADJ
admet-3065	1294	2	anesthesiology	anesthesiology	NOUN
admet-3065	1294	3	reports	report	VERB
admet-3065	1294	4	1	1	NUM
admet-3065	1294	5	(	(	PUNCT
admet-3065	1294	6	2013	2013	NUM
admet-3065	1294	7	)	)	PUNCT
admet-3065	1294	8	63	63	NUM
admet-3065	1294	9	-	-	SYM
admet-3065	1294	10	70	70	NUM
admet-3065	1294	11	.	.	PUNCT
admet-3065	1294	12	https://doi.org/10.1007/s40139-012-0004-5	https://doi.org/10.1007/s40139-012-0004-5	NUM
admet-3065	1295	1	[	[	X
admet-3065	1295	2	240	240	NUM
admet-3065	1295	3	]	]	PUNCT
admet-3065	1295	4	z.	z.	PROPN
admet-3065	1295	5	zhang	zhang	PROPN
admet-3065	1295	6	,	,	PUNCT
admet-3065	1295	7	q.	q.	PROPN
admet-3065	1295	8	huang	huang	PROPN
admet-3065	1295	9	,	,	PUNCT
admet-3065	1295	10	l.	l.	PROPN
admet-3065	1295	11	yu	yu	PROPN
admet-3065	1295	12	,	,	PUNCT
admet-3065	1295	13	d.	d.	PROPN
admet-3065	1295	14	zhu	zhu	PROPN
admet-3065	1295	15	,	,	PUNCT
admet-3065	1295	16	y.	y.	PROPN
admet-3065	1295	17	li	li	PROPN
admet-3065	1295	18	,	,	PUNCT
admet-3065	1295	19	z.	z.	PROPN
admet-3065	1295	20	xue	xue	PROPN
admet-3065	1295	21	,	,	PUNCT
admet-3065	1295	22	z.	z.	PROPN
admet-3065	1295	23	hua	hua	PROPN
admet-3065	1295	24	,	,	PUNCT
admet-3065	1295	25	x.	x.	PROPN
admet-3065	1295	26	luo	luo	PROPN
admet-3065	1295	27	,	,	PUNCT
admet-3065	1295	28	z.	z.	PROPN
admet-3065	1295	29	song	song	PROPN
admet-3065	1295	30	,	,	PUNCT
admet-3065	1295	31	c.	c.	PROPN
admet-3065	1295	32	lu	lu	PROPN
admet-3065	1295	33	,	,	PUNCT
admet-3065	1295	34	t.	t.	PROPN
admet-3065	1295	35	zhao	zhao	PROPN
admet-3065	1295	36	,	,	PUNCT
admet-3065	1295	37	y.	y.	PROPN
admet-3065	1295	38	liu	liu	PROPN
admet-3065	1295	39	.	.	PUNCT
admet-3065	1296	1	the	the	DET
admet-3065	1296	2	role	role	NOUN
admet-3065	1296	3	of	of	ADP
admet-3065	1296	4	mirna	mirna	NOUN
admet-3065	1296	5	in	in	ADP
admet-3065	1296	6	tumor	tumor	NOUN
admet-3065	1296	7	immune	immune	ADJ
admet-3065	1296	8	escape	escape	NOUN
admet-3065	1296	9	and	and	CCONJ
admet-3065	1296	10	mirna	mirna	NOUN
admet-3065	1296	11	-	-	PUNCT
admet-3065	1296	12	based	base	VERB
admet-3065	1296	13	therapeutic	therapeutic	ADJ
admet-3065	1296	14	strategies	strategy	NOUN
admet-3065	1296	15	.	.	PUNCT
admet-3065	1297	1	frontiers	frontier	NOUN
admet-3065	1297	2	in	in	ADP
admet-3065	1297	3	immunology	immunology	NOUN
admet-3065	1297	4	12	12	NUM
admet-3065	1297	5	(	(	PUNCT
admet-3065	1297	6	2022	2022	NUM
admet-3065	1297	7	)	)	PUNCT
admet-3065	1297	8	807895	807895	NUM
admet-3065	1297	9	.	.	PUNCT
admet-3065	1298	1	https://doi.org/10.3389/fimmu.2021.807895	https://doi.org/10.3389/fimmu.2021.807895	PROPN
admet-3065	1298	2	[	[	X
admet-3065	1298	3	241	241	X
admet-3065	1298	4	]	]	X
admet-3065	1298	5	s.	s.	PROPN
admet-3065	1298	6	mehier	mehier	PROPN
admet-3065	1298	7	-	-	PUNCT
admet-3065	1298	8	humbert	humbert	PROPN
admet-3065	1298	9	,	,	PUNCT
admet-3065	1298	10	r.h	r.h	PROPN
admet-3065	1298	11	.	.	PROPN
admet-3065	1298	12	guy	guy	NOUN
admet-3065	1298	13	.	.	PUNCT
admet-3065	1298	14	physical	physical	ADJ
admet-3065	1298	15	methods	method	NOUN
admet-3065	1298	16	for	for	ADP
admet-3065	1298	17	gene	gene	NOUN
admet-3065	1298	18	transfer	transfer	NOUN
admet-3065	1298	19	:	:	PUNCT
admet-3065	1298	20	improving	improve	VERB
admet-3065	1298	21	the	the	DET
admet-3065	1298	22	kinetics	kinetic	NOUN
admet-3065	1298	23	of	of	ADP
admet-3065	1298	24	gene	gene	NOUN
admet-3065	1298	25	delivery	delivery	NOUN
admet-3065	1298	26	into	into	ADP
admet-3065	1298	27	cells	cell	NOUN
admet-3065	1298	28	.	.	PUNCT
admet-3065	1299	1	advanced	advanced	ADJ
admet-3065	1299	2	drug	drug	NOUN
admet-3065	1299	3	delivery	delivery	NOUN
admet-3065	1299	4	reviews	review	VERB
admet-3065	1299	5	57	57	NUM
admet-3065	1299	6	(	(	PUNCT
admet-3065	1299	7	2005	2005	NUM
admet-3065	1299	8	)	)	PUNCT
admet-3065	1299	9	733	733	NUM
admet-3065	1299	10	-	-	SYM
admet-3065	1299	11	753	753	NUM
admet-3065	1299	12	.	.	PUNCT
admet-3065	1300	1	https://doi.org/10.1016/j.addr.2004.12.007	https://doi.org/10.1016/j.addr.2004.12.007	VERB
admet-3065	1300	2	[	[	X
admet-3065	1300	3	242	242	NUM
admet-3065	1300	4	]	]	X
admet-3065	1300	5	m.t	m.t	PROPN
admet-3065	1300	6	.	.	PROPN
admet-3065	1300	7	luiz	luiz	PROPN
admet-3065	1300	8	,	,	PUNCT
admet-3065	1300	9	j.a.p	j.a.p	PROPN
admet-3065	1300	10	.	.	PUNCT
admet-3065	1301	1	dutra	dutra	PROPN
admet-3065	1301	2	,	,	PUNCT
admet-3065	1301	3	l.b	l.b	PROPN
admet-3065	1301	4	.	.	PROPN
admet-3065	1301	5	tofani	tofani	PROPN
admet-3065	1301	6	,	,	PUNCT
admet-3065	1301	7	j.t.c	j.t.c	PROPN
admet-3065	1301	8	.	.	PUNCT
admet-3065	1301	9	de	de	X
admet-3065	1301	10	araújo	araújo	PROPN
admet-3065	1301	11	,	,	PUNCT
admet-3065	1301	12	l.d	l.d	PROPN
admet-3065	1301	13	.	.	PROPN
admet-3065	1301	14	di	di	PROPN
admet-3065	1301	15	filippo	filippo	PROPN
admet-3065	1301	16	,	,	PUNCT
admet-3065	1301	17	j.m	j.m	PROPN
admet-3065	1301	18	.	.	PROPN
admet-3065	1301	19	marchetti	marchetti	PROPN
admet-3065	1301	20	,	,	PUNCT
admet-3065	1301	21	m.	m.	NOUN
admet-3065	1301	22	chorilli	chorilli	PROPN
admet-3065	1301	23	.	.	PUNCT
admet-3065	1302	1	targeted	target	VERB
admet-3065	1302	2	liposomes	liposome	NOUN
admet-3065	1302	3	:	:	PUNCT
admet-3065	1302	4	a	a	DET
admet-3065	1302	5	nonviral	nonviral	ADJ
admet-3065	1302	6	gene	gene	NOUN
admet-3065	1302	7	delivery	delivery	NOUN
admet-3065	1302	8	system	system	NOUN
admet-3065	1302	9	for	for	ADP
admet-3065	1302	10	cancer	cancer	NOUN
admet-3065	1302	11	therapy	therapy	NOUN
admet-3065	1302	12	.	.	PUNCT
admet-3065	1303	1	pharmaceutics	pharmaceutic	NOUN
admet-3065	1303	2	14	14	NUM
admet-3065	1303	3	(	(	PUNCT
admet-3065	1303	4	2022	2022	NUM
admet-3065	1303	5	)	)	PUNCT
admet-3065	1303	6	821	821	NUM
admet-3065	1303	7	-	-	SYM
admet-3065	1303	8	821	821	NUM
admet-3065	1303	9	.	.	PUNCT
admet-3065	1304	1	https://doi.org/10.3390/pharmaceutics14040821	https://doi.org/10.3390/pharmaceutics14040821	NOUN
admet-3065	1305	1	[	[	X
admet-3065	1305	2	243	243	NUM
admet-3065	1305	3	]	]	PUNCT
admet-3065	1305	4	s.	s.	PROPN
admet-3065	1305	5	song	song	PROPN
admet-3065	1305	6	,	,	PUNCT
admet-3065	1305	7	m.j	m.j	PROPN
admet-3065	1305	8	.	.	PROPN
admet-3065	1305	9	lyle	lyle	PROPN
admet-3065	1305	10	,	,	PUNCT
admet-3065	1305	11	m.l	m.l	PROPN
admet-3065	1305	12	.	.	PUNCT
admet-3065	1305	13	noble	noble	ADJ
admet-3065	1305	14	-	-	PUNCT
admet-3065	1305	15	vranish	vranish	ADJ
admet-3065	1305	16	,	,	PUNCT
admet-3065	1305	17	d.m	d.m	PROPN
admet-3065	1305	18	.	.	PUNCT
admet-3065	1306	1	min	min	PROPN
admet-3065	1306	2	-	-	PUNCT
admet-3065	1306	3	tran	tran	PROPN
admet-3065	1306	4	,	,	PUNCT
admet-3065	1306	5	j.	j.	PROPN
admet-3065	1306	6	harrang	harrang	PROPN
admet-3065	1306	7	,	,	PUNCT
admet-3065	1306	8	w.	w.	PROPN
admet-3065	1306	9	xiao	xiao	PROPN
admet-3065	1306	10	,	,	PUNCT
admet-3065	1306	11	e.c	e.c	PROPN
admet-3065	1306	12	.	.	PROPN
admet-3065	1306	13	unger	unger	PROPN
admet-3065	1306	14	,	,	PUNCT
admet-3065	1306	15	c.h	c.h	PROPN
admet-3065	1306	16	.	.	PROPN
admet-3065	1306	17	miao	miao	PROPN
admet-3065	1306	18	.	.	PUNCT
admet-3065	1306	19	ultrasound	ultrasound	NOUN
admet-3065	1306	20	-	-	PUNCT
admet-3065	1306	21	mediated	mediate	VERB
admet-3065	1306	22	gene	gene	NOUN
admet-3065	1306	23	delivery	delivery	NOUN
admet-3065	1306	24	of	of	ADP
admet-3065	1306	25	factor	factor	NOUN
admet-3065	1306	26	viii	viii	NOUN
admet-3065	1306	27	plasmids	plasmid	NOUN
admet-3065	1306	28	for	for	ADP
admet-3065	1306	29	hemophilia	hemophilia	NOUN
admet-3065	1306	30	a	a	DET
admet-3065	1306	31	gene	gene	NOUN
admet-3065	1306	32	therapy	therapy	NOUN
admet-3065	1306	33	in	in	ADP
admet-3065	1306	34	mice	mouse	NOUN
admet-3065	1306	35	.	.	PUNCT
admet-3065	1307	1	molecular	molecular	ADJ
admet-3065	1307	2	therapy	therapy	NOUN
admet-3065	1307	3	nucleic	nucleic	ADJ
admet-3065	1307	4	acids	acid	NOUN
admet-3065	1307	5	27	27	NUM
admet-3065	1307	6	(	(	PUNCT
admet-3065	1307	7	2022	2022	NUM
admet-3065	1307	8	)	)	PUNCT
admet-3065	1307	9	916	916	NUM
admet-3065	1307	10	-	-	SYM
admet-3065	1307	11	926	926	NUM
admet-3065	1307	12	.	.	PUNCT
admet-3065	1308	1	https://doi.org/10.1016/j.omtn.2022.01.006	https://doi.org/10.1016/j.omtn.2022.01.006	ADJ
admet-3065	1308	2	[	[	X
admet-3065	1308	3	244	244	NUM
admet-3065	1308	4	]	]	X
admet-3065	1308	5	c.x	c.x	PROPN
admet-3065	1308	6	.	.	PROPN
admet-3065	1308	7	deng	deng	PROPN
admet-3065	1308	8	,	,	PUNCT
admet-3065	1308	9	f.	f.	PROPN
admet-3065	1308	10	sieling	sieling	PROPN
admet-3065	1308	11	,	,	PUNCT
admet-3065	1308	12	h.	h.	PROPN
admet-3065	1308	13	pan	pan	PROPN
admet-3065	1308	14	,	,	PUNCT
admet-3065	1308	15	j.	j.	PROPN
admet-3065	1308	16	cui	cui	PROPN
admet-3065	1308	17	.	.	PUNCT
admet-3065	1308	18	ultrasound	ultrasound	NOUN
admet-3065	1308	19	-	-	PUNCT
admet-3065	1308	20	induced	induce	VERB
admet-3065	1308	21	cell	cell	NOUN
admet-3065	1308	22	membrane	membrane	NOUN
admet-3065	1308	23	porosity	porosity	NOUN
admet-3065	1308	24	.	.	PUNCT
admet-3065	1309	1	ultrasound	ultrasound	NOUN
admet-3065	1309	2	in	in	ADP
admet-3065	1309	3	medicine	medicine	NOUN
admet-3065	1309	4	and	and	CCONJ
admet-3065	1309	5	biology	biology	NOUN
admet-3065	1309	6	30	30	NUM
admet-3065	1309	7	(	(	PUNCT
admet-3065	1309	8	2004	2004	NUM
admet-3065	1309	9	)	)	PUNCT
admet-3065	1309	10	519	519	NUM
admet-3065	1309	11	-	-	SYM
admet-3065	1309	12	526	526	NUM
admet-3065	1309	13	.	.	PUNCT
admet-3065	1310	1	https://doi.org/10.1016/j.ultrasmedbio.2004.01.005	https://doi.org/10.1016/j.ultrasmedbio.2004.01.005	NUM
admet-3065	1311	1	[	[	X
admet-3065	1311	2	245	245	NUM
admet-3065	1311	3	]	]	X
admet-3065	1311	4	h.d	h.d	PROPN
admet-3065	1311	5	.	.	PROPN
admet-3065	1311	6	liang	liang	PROPN
admet-3065	1311	7	,	,	PUNCT
admet-3065	1311	8	j.	j.	PROPN
admet-3065	1311	9	tang	tang	PROPN
admet-3065	1311	10	,	,	PUNCT
admet-3065	1311	11	m.	m.	NOUN
admet-3065	1311	12	halliwell	halliwell	PROPN
admet-3065	1311	13	.	.	PROPN
admet-3065	1311	14	sonoporation	sonoporation	PROPN
admet-3065	1311	15	,	,	PUNCT
admet-3065	1311	16	drug	drug	NOUN
admet-3065	1311	17	delivery	delivery	NOUN
admet-3065	1311	18	,	,	PUNCT
admet-3065	1311	19	and	and	CCONJ
admet-3065	1311	20	gene	gene	NOUN
admet-3065	1311	21	therapy	therapy	NOUN
admet-3065	1311	22	.	.	PUNCT
admet-3065	1312	1	proceedings	proceeding	NOUN
admet-3065	1312	2	of	of	ADP
admet-3065	1312	3	the	the	DET
admet-3065	1312	4	institution	institution	NOUN
admet-3065	1312	5	of	of	ADP
admet-3065	1312	6	mechanical	mechanical	ADJ
admet-3065	1312	7	engineers	engineer	NOUN
admet-3065	1312	8	.	.	PUNCT
admet-3065	1313	1	part	part	NOUN
admet-3065	1313	2	h	h	PROPN
admet-3065	1313	3	,	,	PUNCT
admet-3065	1313	4	journal	journal	NOUN
admet-3065	1313	5	of	of	ADP
admet-3065	1313	6	engineering	engineering	NOUN
admet-3065	1313	7	in	in	ADP
admet-3065	1313	8	medicine	medicine	NOUN
admet-3065	1313	9	224	224	NUM
admet-3065	1313	10	(	(	PUNCT
admet-3065	1313	11	2010	2010	NUM
admet-3065	1313	12	)	)	PUNCT
admet-3065	1313	13	343	343	NUM
admet-3065	1313	14	-	-	SYM
admet-3065	1313	15	361	361	NUM
admet-3065	1313	16	.	.	PUNCT
admet-3065	1314	1	https://doi.org/10.1243/09544119jeim565	https://doi.org/10.1243/09544119jeim565	ADV
admet-3065	1315	1	[	[	X
admet-3065	1315	2	246	246	NUM
admet-3065	1315	3	]	]	PUNCT
admet-3065	1315	4	c.	c.	PROPN
admet-3065	1315	5	plank	plank	PROPN
admet-3065	1315	6	,	,	PUNCT
admet-3065	1315	7	f.	f.	PROPN
admet-3065	1315	8	scherer	scherer	PROPN
admet-3065	1315	9	,	,	PUNCT
admet-3065	1315	10	u.	u.	PROPN
admet-3065	1315	11	schillinger	schillinger	PROPN
admet-3065	1315	12	,	,	PUNCT
admet-3065	1315	13	c.	c.	PROPN
admet-3065	1315	14	bergemann	bergemann	PROPN
admet-3065	1315	15	,	,	PUNCT
admet-3065	1315	16	m.	m.	NOUN
admet-3065	1315	17	anton	anton	PROPN
admet-3065	1315	18	.	.	PUNCT
admet-3065	1316	1	magnetofection	magnetofection	NOUN
admet-3065	1316	2	:	:	PUNCT
admet-3065	1316	3	enhancing	enhance	VERB
admet-3065	1316	4	and	and	CCONJ
admet-3065	1316	5	targeting	target	VERB
admet-3065	1316	6	gene	gene	NOUN
admet-3065	1316	7	delivery	delivery	NOUN
admet-3065	1316	8	with	with	ADP
admet-3065	1316	9	superparamagnetic	superparamagnetic	ADJ
admet-3065	1316	10	nanoparticles	nanoparticle	NOUN
admet-3065	1316	11	and	and	CCONJ
admet-3065	1316	12	magnetic	magnetic	ADJ
admet-3065	1316	13	fields	field	NOUN
admet-3065	1316	14	.	.	PUNCT
admet-3065	1317	1	journal	journal	NOUN
admet-3065	1317	2	of	of	ADP
admet-3065	1317	3	liposome	liposome	PROPN
admet-3065	1317	4	research	research	NOUN
admet-3065	1317	5	13	13	NUM
admet-3065	1317	6	(	(	PUNCT
admet-3065	1317	7	2003	2003	NUM
admet-3065	1317	8	)	)	PUNCT
admet-3065	1317	9	29	29	NUM
admet-3065	1317	10	-	-	SYM
admet-3065	1317	11	32	32	NUM
admet-3065	1317	12	.	.	PUNCT
admet-3065	1318	1	https://doi.org/10.1081/lpr-120017486	https://doi.org/10.1081/lpr-120017486	PROPN
admet-3065	1319	1	[	[	X
admet-3065	1319	2	247	247	NUM
admet-3065	1319	3	]	]	PUNCT
admet-3065	1319	4	f.	f.	PROPN
admet-3065	1319	5	javani	javani	PROPN
admet-3065	1319	6	jouni	jouni	PROPN
admet-3065	1319	7	,	,	PUNCT
admet-3065	1319	8	j.	j.	PROPN
admet-3065	1319	9	zafari	zafari	PROPN
admet-3065	1319	10	,	,	PUNCT
admet-3065	1319	11	p.	p.	PROPN
admet-3065	1319	12	abdolmaleki	abdolmaleki	PROPN
admet-3065	1319	13	,	,	PUNCT
admet-3065	1319	14	h.	h.	PROPN
admet-3065	1319	15	vazini	vazini	PROPN
admet-3065	1319	16	,	,	PUNCT
admet-3065	1319	17	l.	l.	PROPN
admet-3065	1319	18	ghandi	ghandi	PROPN
admet-3065	1319	19	,	,	PUNCT
admet-3065	1319	20	m.	m.	NOUN
admet-3065	1319	21	satari	satari	PROPN
admet-3065	1319	22	.	.	PUNCT
admet-3065	1320	1	aflatoxin	aflatoxin	NOUN
admet-3065	1320	2	m1	m1	PROPN
admet-3065	1320	3	detoxification	detoxification	NOUN
admet-3065	1320	4	from	from	ADP
admet-3065	1320	5	infected	infected	ADJ
admet-3065	1320	6	milk	milk	NOUN
admet-3065	1320	7	using	use	VERB
admet-3065	1320	8	fe3o4	fe3o4	PROPN
admet-3065	1320	9	nanoparticles	nanoparticle	NOUN
admet-3065	1320	10	attached	attach	VERB
admet-3065	1320	11	to	to	ADP
admet-3065	1320	12	specific	specific	ADJ
admet-3065	1320	13	aptamer	aptamer	NOUN
admet-3065	1320	14	.	.	PUNCT
admet-3065	1321	1	journal	journal	PROPN
admet-3065	1321	2	of	of	ADP
admet-3065	1321	3	nanostructure	nanostructure	NOUN
admet-3065	1321	4	in	in	ADP
admet-3065	1321	5	chemistry	chemistry	NOUN
admet-3065	1321	6	8	8	NUM
admet-3065	1321	7	(	(	PUNCT
admet-3065	1321	8	2018	2018	NUM
admet-3065	1321	9	)	)	PUNCT
admet-3065	1321	10	13	13	NUM
admet-3065	1321	11	-	-	SYM
admet-3065	1321	12	22	22	NUM
admet-3065	1321	13	.	.	PUNCT
admet-3065	1322	1	https://doi.org/10.1007/s40097-017-0250-5/figures/10	https://doi.org/10.1007/s40097-017-0250-5/figures/10	VERB
admet-3065	1322	2	[	[	PUNCT
admet-3065	1322	3	248	248	NUM
admet-3065	1322	4	]	]	PUNCT
admet-3065	1322	5	m.	m.	NOUN
admet-3065	1322	6	satari	satari	NOUN
admet-3065	1322	7	,	,	PUNCT
admet-3065	1322	8	n.	n.	PROPN
admet-3065	1322	9	haghighat	haghighat	PROPN
admet-3065	1322	10	,	,	PUNCT
admet-3065	1322	11	f.	f.	PROPN
admet-3065	1322	12	javani	javani	PROPN
admet-3065	1322	13	jouni	jouni	PROPN
admet-3065	1322	14	,	,	PUNCT
admet-3065	1322	15	p.	p.	PROPN
admet-3065	1322	16	abodolmaleki	abodolmaleki	PROPN
admet-3065	1322	17	.	.	PUNCT
admet-3065	1323	1	the	the	DET
admet-3065	1323	2	effects	effect	NOUN
admet-3065	1323	3	of	of	ADP
admet-3065	1323	4	synthesized	synthesize	VERB
admet-3065	1323	5	superparamagnetic	superparamagnetic	ADJ
admet-3065	1323	6	iron	iron	NOUN
admet-3065	1323	7	oxide	oxide	NOUN
admet-3065	1323	8	nanoparticles	nanoparticle	NOUN
admet-3065	1323	9	and	and	CCONJ
admet-3065	1323	10	electromagnetic	electromagnetic	ADJ
admet-3065	1323	11	field	field	NOUN
admet-3065	1323	12	on	on	ADP
admet-3065	1323	13	cell	cell	NOUN
admet-3065	1323	14	death	death	NOUN
admet-3065	1323	15	of	of	ADP
admet-3065	1323	16	mcf-7	mcf-7	PUNCT
admet-3065	1323	17	breast	breast	NOUN
admet-3065	1323	18	cancer	cancer	NOUN
admet-3065	1323	19	cell	cell	NOUN
admet-3065	1323	20	line	line	NOUN
admet-3065	1323	21	.	.	PUNCT
admet-3065	1324	1	multidisciplinary	multidisciplinary	ADJ
admet-3065	1324	2	cancer	cancer	NOUN
admet-3065	1324	3	investigation	investigation	NOUN
admet-3065	1324	4	2	2	NUM
admet-3065	1324	5	(	(	PUNCT
admet-3065	1324	6	2018	2018	NUM
admet-3065	1324	7	)	)	PUNCT
admet-3065	1324	8	13	13	NUM
admet-3065	1324	9	-	-	SYM
admet-3065	1324	10	21	21	NUM
admet-3065	1324	11	.	.	PUNCT
admet-3065	1325	1	https://doi.org/10.30699/acadpub.mci.2.1.13	https://doi.org/10.30699/acadpub.mci.2.1.13	PRON
admet-3065	1326	1	[	[	X
admet-3065	1326	2	249	249	NUM
admet-3065	1326	3	]	]	PUNCT
admet-3065	1326	4	m.	m.	NOUN
admet-3065	1326	5	satari	satari	NOUN
admet-3065	1326	6	,	,	PUNCT
admet-3065	1326	7	f.j	f.j	PROPN
admet-3065	1326	8	.	.	PROPN
admet-3065	1326	9	jouni	jouni	PROPN
admet-3065	1326	10	,	,	PUNCT
admet-3065	1326	11	p.	p.	PROPN
admet-3065	1326	12	abolmaleki	abolmaleki	PROPN
admet-3065	1326	13	,	,	PUNCT
admet-3065	1326	14	h.	h.	PROPN
admet-3065	1326	15	soleimani	soleimani	PROPN
admet-3065	1326	16	.	.	PUNCT
admet-3065	1327	1	influence	influence	NOUN
admet-3065	1327	2	of	of	ADP
admet-3065	1327	3	static	static	ADJ
admet-3065	1327	4	magnetic	magnetic	ADJ
admet-3065	1327	5	field	field	NOUN
admet-3065	1327	6	on	on	ADP
admet-3065	1327	7	hela	hela	PROPN
admet-3065	1327	8	and	and	CCONJ
admet-3065	1327	9	huo2	huo2	PROPN
admet-3065	1327	10	cells	cell	NOUN
admet-3065	1327	11	in	in	ADP
admet-3065	1327	12	the	the	DET
admet-3065	1327	13	presence	presence	NOUN
admet-3065	1327	14	of	of	ADP
admet-3065	1327	15	aloe	aloe	PROPN
admet-3065	1327	16	vera	vera	NOUN
admet-3065	1327	17	extract	extract	NOUN
admet-3065	1327	18	.	.	PUNCT
admet-3065	1328	1	asian	asian	PROPN
admet-3065	1328	2	pacific	pacific	PROPN
admet-3065	1328	3	journal	journal	PROPN
admet-3065	1328	4	of	of	ADP
admet-3065	1328	5	cancer	cancer	NOUN
admet-3065	1328	6	prevention	prevention	NOUN
admet-3065	1328	7	22	22	NUM
admet-3065	1328	8	(	(	PUNCT
admet-3065	1328	9	2021	2021	NUM
admet-3065	1328	10	)	)	PUNCT
admet-3065	1328	11	9	9	NUM
admet-3065	1328	12	-	-	SYM
admet-3065	1328	13	15	15	NUM
admet-3065	1328	14	.	.	PUNCT
admet-3065	1329	1	https://doi.org/10.31557/apjcp.2021.22.s1.9	https://doi.org/10.31557/apjcp.2021.22.s1.9	PROPN
admet-3065	1329	2	https://doi.org/10.1007/978-1-60761-657-3_10	https://doi.org/10.1007/978-1-60761-657-3_10	PROPN
admet-3065	1329	3	https://doi.org/10.1016/s0076-6879(04)92009-5	https://doi.org/10.1016/s0076-6879(04)92009-5	PROPN
admet-3065	1329	4	https://doi.org/10.1016/s0076-6879(04)92002-2	https://doi.org/10.1016/s0076-6879(04)92002-2	PROPN
admet-3065	1329	5	https://doi.org/10.1385/1-59259-413-1:273	https://doi.org/10.1385/1-59259-413-1:273	PROPN
admet-3065	1329	6	https://doi.org/10.1182/blood-2006-01-030015	https://doi.org/10.1182/blood-2006-01-030015	PROPN
admet-3065	1329	7	https://doi.org/10.1111/j.1469-185x.2008.00061.x	https://doi.org/10.1111/j.1469-185x.2008.00061.x	X
admet-3065	1330	1	https://doi.org/10.1016/j.biopha.2013.10.002	https://doi.org/10.1016/j.biopha.2013.10.002	X
admet-3065	1330	2	https://doi.org/10.1007/s40139-012-0004-5	https://doi.org/10.1007/s40139-012-0004-5	NUM
admet-3065	1330	3	https://doi.org/10.3389/fimmu.2021.807895	https://doi.org/10.3389/fimmu.2021.807895	PROPN
admet-3065	1330	4	https://doi.org/10.1016/j.addr.2004.12.007	https://doi.org/10.1016/j.addr.2004.12.007	VERB
admet-3065	1330	5	https://doi.org/10.3390/pharmaceutics14040821	https://doi.org/10.3390/pharmaceutics14040821	NOUN
admet-3065	1330	6	https://doi.org/10.1016/j.omtn.2022.01.006	https://doi.org/10.1016/j.omtn.2022.01.006	ADJ
admet-3065	1330	7	https://doi.org/10.1016/j.ultrasmedbio.2004.01.005	https://doi.org/10.1016/j.ultrasmedbio.2004.01.005	NUM
admet-3065	1330	8	https://doi.org/10.1243/09544119jeim565	https://doi.org/10.1243/09544119jeim565	NOUN
admet-3065	1330	9	https://doi.org/10.1081/lpr-120017486	https://doi.org/10.1081/lpr-120017486	NOUN
admet-3065	1330	10	https://doi.org/10.1007/s40097-017-0250-5/figures/10	https://doi.org/10.1007/s40097-017-0250-5/figures/10	PROPN
admet-3065	1330	11	https://doi.org/10.30699/acadpub.mci.2.1.13	https://doi.org/10.30699/acadpub.mci.2.1.13	PROPN
admet-3065	1330	12	https://doi.org/10.31557/apjcp.2021.22.s1.9	https://doi.org/10.31557/apjcp.2021.22.s1.9	PROPN
admet-3065	1330	13	admet	admet	PROPN
admet-3065	1330	14	&	&	CCONJ
admet-3065	1330	15	dmpk	dmpk	PROPN
admet-3065	1330	16	00(0	00(0	PROPN
admet-3065	1330	17	)	)	PUNCT
admet-3065	1330	18	(	(	PUNCT
admet-3065	1330	19	2025	2025	NUM
admet-3065	1330	20	)	)	PUNCT
admet-3065	1330	21	3065	3065	NUM
admet-3065	1330	22	liposome	liposome	NOUN
admet-3065	1330	23	-	-	PUNCT
admet-3065	1330	24	mediated	mediate	VERB
admet-3065	1330	25	gene	gene	NOUN
admet-3065	1330	26	delivery	delivery	NOUN
admet-3065	1330	27	doi	doi	NOUN
admet-3065	1330	28	:	:	PUNCT
admet-3065	1330	29	https://doi.org/10.5599/admet.3065	https://doi.org/10.5599/admet.3065	PROPN
admet-3065	1330	30	33	33	NUM
admet-3065	1331	1	[	[	X
admet-3065	1331	2	250	250	NUM
admet-3065	1331	3	]	]	PUNCT
admet-3065	1331	4	j.	j.	PROPN
admet-3065	1331	5	zafari	zafari	PROPN
admet-3065	1331	6	,	,	PUNCT
admet-3065	1331	7	h.	h.	PROPN
admet-3065	1331	8	vazini	vazini	PROPN
admet-3065	1331	9	,	,	PUNCT
admet-3065	1331	10	f.	f.	PROPN
admet-3065	1331	11	javani	javani	PROPN
admet-3065	1331	12	-	-	PUNCT
admet-3065	1331	13	jouni	jouni	PROPN
admet-3065	1331	14	,	,	PUNCT
admet-3065	1331	15	p.	p.	PROPN
admet-3065	1331	16	abdolmaleki	abdolmaleki	PROPN
admet-3065	1331	17	,	,	PUNCT
admet-3065	1331	18	r.	r.	PROPN
admet-3065	1331	19	monajemi	monajemi	PROPN
admet-3065	1331	20	,	,	PUNCT
admet-3065	1331	21	e.	e.	PROPN
admet-3065	1331	22	shams	shams	PROPN
admet-3065	1331	23	,	,	PUNCT
admet-3065	1331	24	m.	m.	NOUN
admet-3065	1331	25	satari	satari	PROPN
admet-3065	1331	26	.	.	PUNCT
admet-3065	1332	1	anticancer	anticancer	NOUN
admet-3065	1332	2	effects	effect	NOUN
admet-3065	1332	3	of	of	ADP
admet-3065	1332	4	moderate	moderate	ADJ
admet-3065	1332	5	static	static	ADJ
admet-3065	1332	6	magnetic	magnetic	ADJ
admet-3065	1332	7	field	field	NOUN
admet-3065	1332	8	on	on	ADP
admet-3065	1332	9	cancer	cancer	NOUN
admet-3065	1332	10	cells	cell	NOUN
admet-3065	1332	11	in	in	ADP
admet-3065	1332	12	vitro	vitro	VERB
admet-3065	1332	13	.	.	PUNCT
admet-3065	1333	1	research	research	NOUN
admet-3065	1333	2	in	in	ADP
admet-3065	1333	3	molecular	molecular	ADJ
admet-3065	1333	4	medicine	medicine	NOUN
admet-3065	1333	5	6	6	NUM
admet-3065	1333	6	(	(	PUNCT
admet-3065	1333	7	2018	2018	NUM
admet-3065	1333	8	)	)	PUNCT
admet-3065	1333	9	54	54	NUM
admet-3065	1333	10	-	-	SYM
admet-3065	1333	11	64	64	NUM
admet-3065	1333	12	.	.	PUNCT
admet-3065	1334	1	https://doi.org/10.18502/rmm.v6i3.4610	https://doi.org/10.18502/rmm.v6i3.4610	PRON
admet-3065	1335	1	[	[	X
admet-3065	1335	2	251	251	NUM
admet-3065	1335	3	]	]	X
admet-3065	1335	4	s.i	s.i	PROPN
admet-3065	1335	5	.	.	PROPN
admet-3065	1335	6	jenkins	jenkins	PROPN
admet-3065	1335	7	,	,	PUNCT
admet-3065	1335	8	m.r	m.r	PROPN
admet-3065	1335	9	.	.	PROPN
admet-3065	1335	10	pickard	pickard	PROPN
admet-3065	1335	11	,	,	PUNCT
admet-3065	1335	12	n.	n.	PROPN
admet-3065	1335	13	granger	granger	PROPN
admet-3065	1335	14	,	,	PUNCT
admet-3065	1335	15	d.m	d.m	PROPN
admet-3065	1335	16	.	.	PUNCT
admet-3065	1335	17	chari	chari	PROPN
admet-3065	1335	18	.	.	PUNCT
admet-3065	1336	1	magnetic	magnetic	ADJ
admet-3065	1336	2	nanoparticle	nanoparticle	NOUN
admet-3065	1336	3	-	-	PUNCT
admet-3065	1336	4	mediated	mediate	VERB
admet-3065	1336	5	gene	gene	NOUN
admet-3065	1336	6	transfer	transfer	NOUN
admet-3065	1336	7	to	to	ADP
admet-3065	1336	8	oligodendrocyte	oligodendrocyte	ADJ
admet-3065	1336	9	precursor	precursor	NOUN
admet-3065	1336	10	cell	cell	NOUN
admet-3065	1336	11	transplant	transplant	NOUN
admet-3065	1336	12	populations	population	NOUN
admet-3065	1336	13	is	be	AUX
admet-3065	1336	14	enhanced	enhance	VERB
admet-3065	1336	15	by	by	ADP
admet-3065	1336	16	magnetofection	magnetofection	NOUN
admet-3065	1336	17	strategies	strategy	NOUN
admet-3065	1336	18	.	.	PUNCT
admet-3065	1337	1	acs	acs	PROPN
admet-3065	1337	2	nano	nano	VERB
admet-3065	1337	3	5	5	NUM
admet-3065	1337	4	(	(	PUNCT
admet-3065	1337	5	2011	2011	NUM
admet-3065	1337	6	)	)	PUNCT
admet-3065	1337	7	6527	6527	NUM
admet-3065	1337	8	-	-	SYM
admet-3065	1337	9	6538	6538	NUM
admet-3065	1337	10	.	.	PUNCT
admet-3065	1338	1	https://doi.org/10.1021/nn2018717	https://doi.org/10.1021/nn2018717	X
admet-3065	1339	1	[	[	X
admet-3065	1339	2	252	252	NUM
admet-3065	1339	3	]	]	PUNCT
admet-3065	1339	4	h.	h.	PROPN
admet-3065	1339	5	potter	potter	PROPN
admet-3065	1339	6	,	,	PUNCT
admet-3065	1339	7	r.	r.	PROPN
admet-3065	1339	8	heller	heller	PROPN
admet-3065	1339	9	.	.	PUNCT
admet-3065	1339	10	transfection	transfection	NOUN
admet-3065	1339	11	by	by	ADP
admet-3065	1339	12	electroporation	electroporation	NOUN
admet-3065	1339	13	.	.	PUNCT
admet-3065	1340	1	current	current	ADJ
admet-3065	1340	2	protocols	protocol	NOUN
admet-3065	1340	3	in	in	ADP
admet-3065	1340	4	molecular	molecular	ADJ
admet-3065	1340	5	biology	biology	NOUN
admet-3065	1340	6	121	121	NUM
admet-3065	1340	7	(	(	PUNCT
admet-3065	1340	8	2018	2018	NUM
admet-3065	1340	9	)	)	PUNCT
admet-3065	1340	10	9.3.1	9.3.1	NUM
admet-3065	1340	11	-	-	SYM
admet-3065	1340	12	9.3.13	9.3.13	NUM
admet-3065	1340	13	.	.	PUNCT
admet-3065	1340	14	https://doi.org/10.1002/cpmb.48	https://doi.org/10.1002/cpmb.48	PUNCT
admet-3065	1341	1	[	[	X
admet-3065	1341	2	253	253	NUM
admet-3065	1341	3	]	]	PUNCT
admet-3065	1341	4	t.	t.	PROPN
admet-3065	1341	5	kotnik	kotnik	PROPN
admet-3065	1341	6	,	,	PUNCT
admet-3065	1341	7	l.	l.	PROPN
admet-3065	1341	8	rems	rems	PROPN
admet-3065	1341	9	,	,	PUNCT
admet-3065	1341	10	m.	m.	NOUN
admet-3065	1341	11	tarek	tarek	PROPN
admet-3065	1341	12	,	,	PUNCT
admet-3065	1341	13	d.	d.	PROPN
admet-3065	1341	14	miklavcic	miklavcic	PROPN
admet-3065	1341	15	.	.	PUNCT
admet-3065	1342	1	membrane	membrane	NOUN
admet-3065	1342	2	electroporation	electroporation	NOUN
admet-3065	1342	3	and	and	CCONJ
admet-3065	1342	4	electropermeabilization	electropermeabilization	NOUN
admet-3065	1342	5	:	:	PUNCT
admet-3065	1342	6	mechanisms	mechanism	NOUN
admet-3065	1342	7	and	and	CCONJ
admet-3065	1342	8	models	model	NOUN
admet-3065	1342	9	.	.	PUNCT
admet-3065	1343	1	annual	annual	ADJ
admet-3065	1343	2	review	review	NOUN
admet-3065	1343	3	of	of	ADP
admet-3065	1343	4	biophysics	biophysic	NOUN
admet-3065	1343	5	48	48	NUM
admet-3065	1343	6	(	(	PUNCT
admet-3065	1343	7	2019	2019	NUM
admet-3065	1343	8	)	)	PUNCT
admet-3065	1343	9	63	63	NUM
admet-3065	1343	10	-	-	SYM
admet-3065	1343	11	91	91	NUM
admet-3065	1343	12	.	.	PUNCT
admet-3065	1344	1	https://doi.org/10.1146/annurev-biophys-052118-115451	https://doi.org/10.1146/annurev-biophys-052118-115451	PROPN
admet-3065	1345	1	[	[	X
admet-3065	1345	2	254	254	NUM
admet-3065	1345	3	]	]	X
admet-3065	1345	4	e.t	e.t	PROPN
admet-3065	1345	5	.	.	PROPN
admet-3065	1345	6	jordan	jordan	PROPN
admet-3065	1345	7	,	,	PUNCT
admet-3065	1345	8	m.	m.	NOUN
admet-3065	1345	9	collins	collins	PROPN
admet-3065	1345	10	,	,	PUNCT
admet-3065	1345	11	j.	j.	PROPN
admet-3065	1345	12	terefe	terefe	PROPN
admet-3065	1345	13	,	,	PUNCT
admet-3065	1345	14	l.	l.	PROPN
admet-3065	1345	15	ugozzoli	ugozzoli	PROPN
admet-3065	1345	16	,	,	PUNCT
admet-3065	1345	17	t.	t.	NOUN
admet-3065	1345	18	rubio	rubio	NOUN
admet-3065	1345	19	.	.	PUNCT
admet-3065	1346	1	optimizing	optimize	VERB
admet-3065	1346	2	electroporation	electroporation	NOUN
admet-3065	1346	3	conditions	condition	NOUN
admet-3065	1346	4	in	in	ADP
admet-3065	1346	5	primary	primary	ADJ
admet-3065	1346	6	and	and	CCONJ
admet-3065	1346	7	other	other	ADJ
admet-3065	1346	8	difficult	difficult	ADJ
admet-3065	1346	9	-	-	PUNCT
admet-3065	1346	10	to	to	ADP
admet-3065	1346	11	-	-	PUNCT
admet-3065	1346	12	transfect	transfect	NOUN
admet-3065	1346	13	cells	cell	NOUN
admet-3065	1346	14	.	.	PUNCT
admet-3065	1347	1	journal	journal	NOUN
admet-3065	1347	2	of	of	ADP
admet-3065	1347	3	biomolecular	biomolecular	ADJ
admet-3065	1347	4	techniques	technique	NOUN
admet-3065	1347	5	19	19	NUM
admet-3065	1347	6	(	(	PUNCT
admet-3065	1347	7	2008	2008	NUM
admet-3065	1347	8	)	)	PUNCT
admet-3065	1347	9	328	328	NUM
admet-3065	1348	1	[	[	X
admet-3065	1348	2	255	255	NUM
admet-3065	1348	3	]	]	X
admet-3065	1348	4	s.	s.	PROPN
admet-3065	1348	5	hosseinpour	hosseinpour	PROPN
admet-3065	1348	6	,	,	PUNCT
admet-3065	1348	7	l.j	l.j	PROPN
admet-3065	1348	8	.	.	PROPN
admet-3065	1348	9	walsh	walsh	PROPN
admet-3065	1348	10	.	.	PUNCT
admet-3065	1349	1	laser	laser	NOUN
admet-3065	1349	2	-	-	PUNCT
admet-3065	1349	3	assisted	assist	VERB
admet-3065	1349	4	nucleic	nucleic	ADJ
admet-3065	1349	5	acid	acid	NOUN
admet-3065	1349	6	delivery	delivery	NOUN
admet-3065	1349	7	:	:	PUNCT
admet-3065	1349	8	a	a	DET
admet-3065	1349	9	systematic	systematic	ADJ
admet-3065	1349	10	review	review	NOUN
admet-3065	1349	11	.	.	PUNCT
admet-3065	1350	1	journal	journal	PROPN
admet-3065	1350	2	of	of	ADP
admet-3065	1350	3	biophotonics	biophotonics	PROPN
admet-3065	1350	4	14	14	NUM
admet-3065	1350	5	(	(	PUNCT
admet-3065	1350	6	2021	2021	NUM
admet-3065	1350	7	)	)	PUNCT
admet-3065	1350	8	202000295	202000295	NUM
admet-3065	1350	9	.	.	PUNCT
admet-3065	1351	1	https://doi.org/10.1002/jbio.202000295	https://doi.org/10.1002/jbio.202000295	NOUN
admet-3065	1351	2	[	[	X
admet-3065	1351	3	256	256	NUM
admet-3065	1351	4	]	]	PUNCT
admet-3065	1351	5	c.-p	c.-p	PROPN
admet-3065	1351	6	.	.	PUNCT
admet-3065	1352	1	yao	yao	PROPN
admet-3065	1352	2	,	,	PUNCT
admet-3065	1352	3	z.-x	z.-x	PROPN
admet-3065	1352	4	.	.	PUNCT
admet-3065	1353	1	zhang	zhang	PROPN
admet-3065	1353	2	,	,	PUNCT
admet-3065	1353	3	r.	r.	PROPN
admet-3065	1353	4	rahmanzadeh	rahmanzadeh	PROPN
admet-3065	1353	5	,	,	PUNCT
admet-3065	1353	6	g.	g.	PROPN
admet-3065	1353	7	huettmann	huettmann	PROPN
admet-3065	1353	8	.	.	PUNCT
admet-3065	1354	1	laser	laser	NOUN
admet-3065	1354	2	-	-	PUNCT
admet-3065	1354	3	based	base	VERB
admet-3065	1354	4	gene	gene	NOUN
admet-3065	1354	5	transfection	transfection	NOUN
admet-3065	1354	6	and	and	CCONJ
admet-3065	1354	7	gene	gene	NOUN
admet-3065	1354	8	therapy	therapy	NOUN
admet-3065	1354	9	.	.	PUNCT
admet-3065	1355	1	ieee	ieee	NOUN
admet-3065	1355	2	transactions	transaction	NOUN
admet-3065	1355	3	on	on	ADP
admet-3065	1355	4	nanobioscience	nanobioscience	NOUN
admet-3065	1355	5	7	7	NUM
admet-3065	1355	6	(	(	PUNCT
admet-3065	1355	7	2008	2008	NUM
admet-3065	1355	8	)	)	PUNCT
admet-3065	1355	9	111	111	NUM
admet-3065	1355	10	-	-	SYM
admet-3065	1355	11	119	119	NUM
admet-3065	1355	12	.	.	PUNCT
admet-3065	1356	1	https://doi.org/10.1109/tnb.2008.2000742	https://doi.org/10.1109/tnb.2008.2000742	X
admet-3065	1356	2	.	.	PUNCT
admet-3065	1357	1	©	©	PROPN
admet-3065	1357	2	2025	2025	NUM
admet-3065	1357	3	by	by	ADP
admet-3065	1357	4	the	the	DET
admet-3065	1357	5	authors	author	NOUN
admet-3065	1357	6	;	;	PUNCT
admet-3065	1357	7	licensee	licensee	PROPN
admet-3065	1357	8	iapc	iapc	PROPN
admet-3065	1357	9	,	,	PUNCT
admet-3065	1357	10	zagreb	zagreb	PROPN
admet-3065	1357	11	,	,	PUNCT
admet-3065	1357	12	croatia	croatia	PROPN
admet-3065	1357	13	.	.	PUNCT
admet-3065	1358	1	this	this	DET
admet-3065	1358	2	article	article	NOUN
admet-3065	1358	3	is	be	AUX
admet-3065	1358	4	an	an	DET
admet-3065	1358	5	open	open	ADJ
admet-3065	1358	6	-	-	PUNCT
admet-3065	1358	7	access	access	NOUN
admet-3065	1358	8	article	article	NOUN
admet-3065	1358	9	distributed	distribute	VERB
admet-3065	1358	10	under	under	ADP
admet-3065	1358	11	the	the	DET
admet-3065	1358	12	terms	term	NOUN
admet-3065	1358	13	and	and	CCONJ
admet-3065	1358	14	conditions	condition	NOUN
admet-3065	1358	15	of	of	ADP
admet-3065	1358	16	the	the	DET
admet-3065	1358	17	creative	creative	ADJ
admet-3065	1358	18	commons	common	NOUN
admet-3065	1358	19	attribution	attribution	NOUN
admet-3065	1358	20	license	license	NOUN
admet-3065	1358	21	(	(	PUNCT
admet-3065	1358	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-3065	1358	23	)	)	PUNCT
admet-3065	1358	24	https://doi.org/10.18502/rmm.v6i3.4610	https://doi.org/10.18502/rmm.v6i3.4610	PROPN
admet-3065	1358	25	https://doi.org/10.1021/nn2018717	https://doi.org/10.1021/nn2018717	NOUN
admet-3065	1358	26	https://doi.org/10.1002/cpmb.48	https://doi.org/10.1002/cpmb.48	X
admet-3065	1359	1	https://doi.org/10.1146/annurev-biophys-052118-115451	https://doi.org/10.1146/annurev-biophys-052118-115451	PROPN
admet-3065	1359	2	https://doi.org/10.1002/jbio.202000295	https://doi.org/10.1002/jbio.202000295	VERB
admet-3065	1359	3	https://doi.org/10.1109/tnb.2008.2000742	https://doi.org/10.1109/tnb.2008.2000742	ADV
admet-3065	1359	4	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN