id	sid	tid	token	lemma	pos
admet-34	1	1	manuscript	manuscript	PROPN
admet-34	1	2	doi	doi	PROPN
admet-34	1	3	:	:	PUNCT
admet-34	1	4	10.5599	10.5599	NUM
admet-34	1	5	/	/	SYM
admet-34	1	6	admet.2.2.34	admet.2.2.34	PROPN
admet-34	1	7	80	80	NUM
admet-34	1	8	admet	admet	NOUN
admet-34	1	9	&	&	CCONJ
admet-34	1	10	dmpk	dmpk	PROPN
admet-34	1	11	2(2	2(2	NUM
admet-34	1	12	)	)	PUNCT
admet-34	1	13	(	(	PUNCT
admet-34	1	14	2014	2014	NUM
admet-34	1	15	)	)	PUNCT
admet-34	1	16	80	80	NUM
admet-34	1	17	-	-	SYM
admet-34	1	18	97	97	NUM
admet-34	1	19	;	;	PUNCT
admet-34	1	20	doi	doi	NOUN
admet-34	1	21	:	:	PUNCT
admet-34	1	22	10.5599	10.5599	NUM
admet-34	1	23	/	/	SYM
admet-34	1	24	admet.2.2.34	admet.2.2.34	ADP
admet-34	1	25	open	open	ADJ
admet-34	1	26	access	access	NOUN
admet-34	1	27	:	:	PUNCT
admet-34	1	28	issn	issn	PROPN
admet-34	1	29	:	:	PUNCT
admet-34	1	30	1848	1848	NUM
admet-34	1	31	-	-	SYM
admet-34	1	32	7718	7718	NUM
admet-34	1	33	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-34	1	34	original	original	ADJ
admet-34	1	35	scientific	scientific	ADJ
admet-34	1	36	paper	paper	NOUN
admet-34	1	37	a	a	DET
admet-34	1	38	physiologically	physiologically	ADV
admet-34	1	39	-	-	PUNCT
admet-34	1	40	oriented	orient	VERB
admet-34	1	41	mathematical	mathematical	ADJ
admet-34	1	42	model	model	NOUN
admet-34	1	43	for	for	ADP
admet-34	1	44	the	the	DET
admet-34	1	45	description	description	NOUN
admet-34	1	46	of	of	ADP
admet-34	1	47	in	in	ADP
admet-34	1	48	vivo	vivo	ADJ
admet-34	1	49	drug	drug	NOUN
admet-34	1	50	release	release	NOUN
admet-34	1	51	and	and	CCONJ
admet-34	1	52	absorption	absorption	NOUN
admet-34	1	53	renzo	renzo	VERB
admet-34	1	54	del	del	PROPN
admet-34	1	55	cont1	cont1	PROPN
admet-34	1	56	,	,	PUNCT
admet-34	1	57	michela	michela	PROPN
admet-34	1	58	abrami1	abrami1	PROPN
admet-34	1	59	,	,	PUNCT
admet-34	1	60	dritan	dritan	PROPN
admet-34	1	61	hasa2	hasa2	NOUN
admet-34	1	62	,	,	PUNCT
admet-34	1	63	beatrice	beatrice	PROPN
admet-34	1	64	perissutti2	perissutti2	PROPN
admet-34	1	65	,	,	PUNCT
admet-34	1	66	dario	dario	NOUN
admet-34	1	67	voinovich2	voinovich2	PROPN
admet-34	1	68	,	,	PUNCT
admet-34	1	69	anna	anna	PROPN
admet-34	1	70	barba3	barba3	PROPN
admet-34	1	71	,	,	PUNCT
admet-34	1	72	gaetano	gaetano	PROPN
admet-34	1	73	lamberti4	lamberti4	PROPN
admet-34	1	74	,	,	PUNCT
admet-34	1	75	gabriele	gabriele	PROPN
admet-34	1	76	grassi5	grassi5	PROPN
admet-34	1	77	,	,	PUNCT
admet-34	1	78	italo	italo	PROPN
admet-34	1	79	colombo1	colombo1	PROPN
admet-34	1	80	,	,	PUNCT
admet-34	1	81	davide	davide	PROPN
admet-34	1	82	manca6	manca6	PROPN
admet-34	1	83	,	,	PUNCT
admet-34	1	84	mario	mario	PROPN
admet-34	1	85	grassi1	grassi1	PROPN
admet-34	1	86	*	*	PROPN
admet-34	1	87	1	1	NUM
admet-34	1	88	dept	dept	NOUN
admet-34	1	89	.	.	PROPN
admet-34	2	1	of	of	ADP
admet-34	2	2	engineering	engineering	NOUN
admet-34	2	3	and	and	CCONJ
admet-34	2	4	architecture	architecture	NOUN
admet-34	2	5	,	,	PUNCT
admet-34	2	6	trieste	trieste	NOUN
admet-34	2	7	university	university	NOUN
admet-34	2	8	,	,	PUNCT
admet-34	2	9	via	via	ADP
admet-34	2	10	alfonso	alfonso	PROPN
admet-34	2	11	valerio	valerio	PROPN
admet-34	2	12	,	,	PUNCT
admet-34	2	13	6	6	NUM
admet-34	2	14	/	/	SYM
admet-34	2	15	a	a	PRON
admet-34	2	16	,	,	PUNCT
admet-34	2	17	trieste	trieste	ADJ
admet-34	2	18	,	,	PUNCT
admet-34	2	19	i-34127	i-34127	PROPN
admet-34	2	20	italy	italy	PROPN
admet-34	2	21	2	2	NUM
admet-34	2	22	dept	dept	NOUN
admet-34	2	23	.	.	PROPN
admet-34	3	1	of	of	ADP
admet-34	3	2	chemical	chemical	NOUN
admet-34	3	3	and	and	CCONJ
admet-34	3	4	pharmaceutical	pharmaceutical	NOUN
admet-34	3	5	sciences	science	NOUN
admet-34	3	6	,	,	PUNCT
admet-34	3	7	trieste	trieste	NOUN
admet-34	3	8	university	university	NOUN
admet-34	3	9	,	,	PUNCT
admet-34	3	10	piazzale	piazzale	PROPN
admet-34	3	11	europa	europa	PROPN
admet-34	3	12	1	1	NUM
admet-34	3	13	,	,	PUNCT
admet-34	3	14	trieste	trieste	ADJ
admet-34	3	15	,	,	PUNCT
admet-34	3	16	i-34127	i-34127	PROPN
admet-34	3	17	,	,	PUNCT
admet-34	3	18	italy	italy	PROPN
admet-34	3	19	3	3	NUM
admet-34	3	20	dept	dept	PROPN
admet-34	3	21	.	.	PROPN
admet-34	4	1	of	of	ADP
admet-34	4	2	pharmacy	pharmacy	NOUN
admet-34	4	3	,	,	PUNCT
admet-34	4	4	salerno	salerno	PROPN
admet-34	4	5	university	university	NOUN
admet-34	4	6	,	,	PUNCT
admet-34	4	7	via	via	ADP
admet-34	4	8	giovanni	giovanni	PROPN
admet-34	4	9	paolo	paolo	PROPN
admet-34	4	10	ii	ii	PROPN
admet-34	4	11	,	,	PUNCT
admet-34	4	12	132	132	NUM
admet-34	4	13	,	,	PUNCT
admet-34	4	14	fisciano	fisciano	ADJ
admet-34	4	15	(	(	PUNCT
admet-34	4	16	sa	sa	NOUN
admet-34	4	17	)	)	PUNCT
admet-34	4	18	,	,	PUNCT
admet-34	4	19	i	i	PRON
admet-34	4	20	84084	84084	NUM
admet-34	4	21	italy	italy	PROPN
admet-34	4	22	4	4	NUM
admet-34	4	23	dept	dept	PROPN
admet-34	4	24	.	.	PROPN
admet-34	5	1	of	of	ADP
admet-34	5	2	industrial	industrial	ADJ
admet-34	5	3	engineering	engineering	NOUN
admet-34	5	4	,	,	PUNCT
admet-34	5	5	salerno	salerno	PROPN
admet-34	5	6	university	university	NOUN
admet-34	5	7	,	,	PUNCT
admet-34	5	8	via	via	ADP
admet-34	5	9	giovanni	giovanni	PROPN
admet-34	5	10	paolo	paolo	PROPN
admet-34	5	11	ii	ii	PROPN
admet-34	5	12	,	,	PUNCT
admet-34	5	13	132	132	NUM
admet-34	5	14	,	,	PUNCT
admet-34	5	15	fisciano	fisciano	ADJ
admet-34	5	16	(	(	PUNCT
admet-34	5	17	sa	sa	NOUN
admet-34	5	18	)	)	PUNCT
admet-34	5	19	,	,	PUNCT
admet-34	5	20	i	i	PRON
admet-34	5	21	84084	84084	NUM
admet-34	5	22	italy	italy	PROPN
admet-34	5	23	5	5	NUM
admet-34	5	24	dept	dept	PROPN
admet-34	5	25	.	.	PROPN
admet-34	6	1	of	of	ADP
admet-34	6	2	life	life	NOUN
admet-34	6	3	sciences	sciences	PROPN
admet-34	6	4	,	,	PUNCT
admet-34	6	5	cattinara	cattinara	NOUN
admet-34	6	6	university	university	PROPN
admet-34	6	7	hospital	hospital	NOUN
admet-34	6	8	,	,	PUNCT
admet-34	6	9	trieste	trieste	NOUN
admet-34	6	10	university	university	NOUN
admet-34	6	11	,	,	PUNCT
admet-34	7	1	strada	strada	PROPN
admet-34	7	2	di	di	PROPN
admet-34	7	3	fiume	fiume	PROPN
admet-34	7	4	447	447	NUM
admet-34	7	5	,	,	PUNCT
admet-34	7	6	trieste	trieste	ADJ
admet-34	7	7	,	,	PUNCT
admet-34	7	8	i-34149	i-34149	PROPN
admet-34	7	9	italy	italy	PROPN
admet-34	7	10	5	5	NUM
admet-34	7	11	dept	dept	NOUN
admet-34	7	12	.	.	PROPN
admet-34	7	13	of	of	ADP
admet-34	7	14	life	life	NOUN
admet-34	7	15	sciences	sciences	PROPN
admet-34	7	16	,	,	PUNCT
admet-34	7	17	cattinara	cattinara	NOUN
admet-34	7	18	university	university	PROPN
admet-34	7	19	hospital	hospital	NOUN
admet-34	7	20	,	,	PUNCT
admet-34	7	21	trieste	trieste	NOUN
admet-34	7	22	university	university	NOUN
admet-34	7	23	,	,	PUNCT
admet-34	7	24	strada	strada	PROPN
admet-34	7	25	di	di	PROPN
admet-34	7	26	fiume	fiume	PROPN
admet-34	7	27	447	447	NUM
admet-34	7	28	,	,	PUNCT
admet-34	7	29	trieste	trieste	ADJ
admet-34	7	30	,	,	PUNCT
admet-34	7	31	i-34149	i-34149	PROPN
admet-34	7	32	italy	italy	PROPN
admet-34	7	33	6	6	NUM
admet-34	7	34	dept	dept	NOUN
admet-34	7	35	.	.	PROPN
admet-34	7	36	of	of	ADP
admet-34	7	37	chemistry	chemistry	NOUN
admet-34	7	38	,	,	PUNCT
admet-34	7	39	materials	material	NOUN
admet-34	7	40	and	and	CCONJ
admet-34	7	41	chemical	chemical	NOUN
admet-34	7	42	engineering	engineering	NOUN
admet-34	7	43	"	"	PUNCT
admet-34	7	44	giulio	giulio	PROPN
admet-34	7	45	natta	natta	PROPN
admet-34	7	46	"	"	PUNCT
admet-34	7	47	politecnico	politecnico	PROPN
admet-34	7	48	di	di	X
admet-34	7	49	milano	milano	PROPN
admet-34	7	50	,	,	PUNCT
admet-34	8	1	p.zza	p.zza	VERB
admet-34	8	2	leonardo	leonardo	PROPN
admet-34	8	3	da	da	PROPN
admet-34	8	4	vinci	vinci	PROPN
admet-34	8	5	,	,	PUNCT
admet-34	8	6	32	32	NUM
admet-34	8	7	–	–	PUNCT
admet-34	8	8	milano	milano	PROPN
admet-34	8	9	,	,	PUNCT
admet-34	8	10	i-20133	i-20133	PROPN
admet-34	8	11	italy	italy	PROPN
admet-34	8	12	.	.	PUNCT
admet-34	9	1	*	*	PUNCT
admet-34	9	2	corresponding	correspond	VERB
admet-34	9	3	author	author	NOUN
admet-34	9	4	:	:	PUNCT
admet-34	9	5	e	e	NOUN
admet-34	9	6	-	-	NOUN
admet-34	9	7	mail	mail	NOUN
admet-34	9	8	:	:	PUNCT
admet-34	9	9	mariog@dicamp.univ.trieste.it	mariog@dicamp.univ.trieste.it	PROPN
admet-34	9	10	;	;	PUNCT
admet-34	9	11	tel	tel	PROPN
admet-34	9	12	.	.	PUNCT
admet-34	9	13	:	:	PUNCT
admet-34	10	1	+39	+39	PROPN
admet-34	10	2	-	-	PUNCT
admet-34	10	3	040	040	NUM
admet-34	10	4	-	-	NUM
admet-34	10	5	558	558	NUM
admet-34	10	6	-	-	SYM
admet-34	10	7	3435	3435	NUM
admet-34	10	8	;	;	PUNCT
admet-34	10	9	fax	fax	NOUN
admet-34	10	10	:	:	PUNCT
admet-34	10	11	+39	+39	PROPN
admet-34	10	12	-	-	PUNCT
admet-34	10	13	040	040	NUM
admet-34	10	14	-	-	SYM
admet-34	10	15	569823	569823	NUM
admet-34	10	16	received	receive	VERB
admet-34	10	17	:	:	PUNCT
admet-34	10	18	march	march	PROPN
admet-34	10	19	02	02	NUM
admet-34	10	20	,	,	PUNCT
admet-34	10	21	2014	2014	NUM
admet-34	10	22	;	;	PUNCT
admet-34	10	23	revised	revise	VERB
admet-34	10	24	:	:	PUNCT
admet-34	10	25	july	july	PROPN
admet-34	10	26	16	16	NUM
admet-34	10	27	,	,	PUNCT
admet-34	10	28	2014	2014	NUM
admet-34	10	29	;	;	PUNCT
admet-34	10	30	published	publish	VERB
admet-34	10	31	:	:	PUNCT
admet-34	10	32	july	july	PROPN
admet-34	10	33	18	18	NUM
admet-34	10	34	,	,	PUNCT
admet-34	10	35	2014	2014	NUM
admet-34	10	36	abstract	abstract	ADV
admet-34	10	37	this	this	DET
admet-34	10	38	paper	paper	NOUN
admet-34	10	39	focuses	focus	VERB
admet-34	10	40	on	on	ADP
admet-34	10	41	a	a	DET
admet-34	10	42	physiologically	physiologically	ADV
admet-34	10	43	-	-	PUNCT
admet-34	10	44	oriented	orient	VERB
admet-34	10	45	mathematical	mathematical	ADJ
admet-34	10	46	model	model	NOUN
admet-34	10	47	aimed	aim	VERB
admet-34	10	48	at	at	ADP
admet-34	10	49	studying	study	VERB
admet-34	10	50	the	the	DET
admet-34	10	51	in	in	ADP
admet-34	10	52	vivo	vivo	ADJ
admet-34	10	53	drug	drug	NOUN
admet-34	10	54	release	release	NOUN
admet-34	10	55	,	,	PUNCT
admet-34	10	56	absorption	absorption	NOUN
admet-34	10	57	,	,	PUNCT
admet-34	10	58	distribution	distribution	NOUN
admet-34	10	59	,	,	PUNCT
admet-34	10	60	metabolism	metabolism	NOUN
admet-34	10	61	and	and	CCONJ
admet-34	10	62	elimination	elimination	NOUN
admet-34	10	63	(	(	PUNCT
admet-34	10	64	adme	adme	NOUN
admet-34	10	65	)	)	PUNCT
admet-34	10	66	.	.	PUNCT
admet-34	11	1	to	to	ADP
admet-34	11	2	this	this	DET
admet-34	11	3	purpose	purpose	NOUN
admet-34	11	4	,	,	PUNCT
admet-34	11	5	the	the	DET
admet-34	11	6	model	model	NOUN
admet-34	11	7	accounts	account	VERB
admet-34	11	8	for	for	ADP
admet-34	11	9	drug	drug	NOUN
admet-34	11	10	delivery	delivery	NOUN
admet-34	11	11	from	from	ADP
admet-34	11	12	an	an	DET
admet-34	11	13	ensemble	ensemble	NOUN
admet-34	11	14	of	of	ADP
admet-34	11	15	non	non	ADJ
admet-34	11	16	-	-	ADJ
admet-34	11	17	eroding	eroding	ADJ
admet-34	11	18	poly	poly	ADJ
admet-34	11	19	-	-	PUNCT
admet-34	11	20	disperse	disperse	NOUN
admet-34	11	21	polymeric	polymeric	ADJ
admet-34	11	22	particles	particle	NOUN
admet-34	11	23	and	and	CCONJ
admet-34	11	24	the	the	DET
admet-34	11	25	subsequent	subsequent	ADJ
admet-34	11	26	adme	adme	NOUN
admet-34	11	27	processes	process	NOUN
admet-34	11	28	.	.	PUNCT
admet-34	12	1	the	the	DET
admet-34	12	2	model	model	NOUN
admet-34	12	3	outcomes	outcome	NOUN
admet-34	12	4	are	be	AUX
admet-34	12	5	studied	study	VERB
admet-34	12	6	with	with	ADP
admet-34	12	7	reference	reference	NOUN
admet-34	12	8	to	to	ADP
admet-34	12	9	three	three	NUM
admet-34	12	10	widely	widely	ADV
admet-34	12	11	used	use	VERB
admet-34	12	12	drugs	drug	NOUN
admet-34	12	13	:	:	PUNCT
admet-34	12	14	theophylline	theophylline	NOUN
admet-34	12	15	,	,	PUNCT
admet-34	12	16	temazepam	temazepam	NOUN
admet-34	12	17	and	and	CCONJ
admet-34	12	18	nimesulide	nimesulide	NOUN
admet-34	12	19	.	.	PUNCT
admet-34	13	1	one	one	NUM
admet-34	13	2	of	of	ADP
admet-34	13	3	the	the	DET
admet-34	13	4	most	most	ADV
admet-34	13	5	important	important	ADJ
admet-34	13	6	results	result	NOUN
admet-34	13	7	of	of	ADP
admet-34	13	8	this	this	DET
admet-34	13	9	study	study	NOUN
admet-34	13	10	is	be	AUX
admet-34	13	11	the	the	DET
admet-34	13	12	quantitative	quantitative	ADJ
admet-34	13	13	evaluation	evaluation	NOUN
admet-34	13	14	of	of	ADP
admet-34	13	15	the	the	DET
admet-34	13	16	interplay	interplay	NOUN
admet-34	13	17	between	between	ADP
admet-34	13	18	the	the	DET
admet-34	13	19	release	release	NOUN
admet-34	13	20	kinetics	kinetic	NOUN
admet-34	13	21	and	and	CCONJ
admet-34	13	22	the	the	DET
admet-34	13	23	subsequent	subsequent	ADJ
admet-34	13	24	adme	adme	NOUN
admet-34	13	25	processes	process	NOUN
admet-34	13	26	.	.	PUNCT
admet-34	14	1	indeed	indeed	ADV
admet-34	14	2	,	,	PUNCT
admet-34	14	3	it	it	PRON
admet-34	14	4	is	be	AUX
admet-34	14	5	usually	usually	ADV
admet-34	14	6	assumed	assume	VERB
admet-34	14	7	that	that	SCONJ
admet-34	14	8	in	in	ADP
admet-34	14	9	vivo	vivo	ADJ
admet-34	14	10	drug	drug	NOUN
admet-34	14	11	release	release	NOUN
admet-34	14	12	coincides	coincide	VERB
admet-34	14	13	with	with	ADP
admet-34	14	14	in	in	ADP
admet-34	14	15	vitro	vitro	X
admet-34	14	16	so	so	SCONJ
admet-34	14	17	that	that	SCONJ
admet-34	14	18	the	the	DET
admet-34	14	19	effect	effect	NOUN
admet-34	14	20	exerted	exert	VERB
admet-34	14	21	by	by	ADP
admet-34	14	22	the	the	DET
admet-34	14	23	adme	adme	NOUN
admet-34	14	24	processes	process	NOUN
admet-34	14	25	is	be	AUX
admet-34	14	26	neglected	neglect	VERB
admet-34	14	27	.	.	PUNCT
admet-34	15	1	in	in	ADP
admet-34	15	2	addition	addition	NOUN
admet-34	15	3	,	,	PUNCT
admet-34	15	4	the	the	DET
admet-34	15	5	proposed	propose	VERB
admet-34	15	6	model	model	NOUN
admet-34	15	7	may	may	AUX
admet-34	15	8	be	be	AUX
admet-34	15	9	an	an	DET
admet-34	15	10	important	important	ADJ
admet-34	15	11	tool	tool	NOUN
admet-34	15	12	for	for	ADP
admet-34	15	13	the	the	DET
admet-34	15	14	design	design	NOUN
admet-34	15	15	of	of	ADP
admet-34	15	16	delivery	delivery	NOUN
admet-34	15	17	systems	system	NOUN
admet-34	15	18	since	since	ADV
admet-34	15	19	,	,	PUNCT
admet-34	15	20	through	through	ADP
admet-34	15	21	proper	proper	ADJ
admet-34	15	22	changes	change	NOUN
admet-34	15	23	,	,	PUNCT
admet-34	15	24	it	it	PRON
admet-34	15	25	could	could	AUX
admet-34	15	26	also	also	ADV
admet-34	15	27	account	account	VERB
admet-34	15	28	for	for	ADP
admet-34	15	29	different	different	ADJ
admet-34	15	30	oral	oral	ADJ
admet-34	15	31	delivery	delivery	NOUN
admet-34	15	32	systems	system	NOUN
admet-34	15	33	.	.	PUNCT
admet-34	16	1	keywords	keyword	NOUN
admet-34	16	2	mathematical	mathematical	ADJ
admet-34	16	3	modelling	modelling	NOUN
admet-34	16	4	,	,	PUNCT
admet-34	16	5	in	in	ADP
admet-34	16	6	vitro	vitro	X
admet-34	16	7	release	release	NOUN
admet-34	16	8	,	,	PUNCT
admet-34	16	9	in	in	ADP
admet-34	16	10	vivo	vivo	NOUN
admet-34	16	11	release	release	NOUN
admet-34	16	12	,	,	PUNCT
admet-34	16	13	pharmacokinetics	pharmacokinetic	NOUN
admet-34	16	14	.	.	PUNCT
admet-34	17	1	introduction	introduction	NOUN
admet-34	17	2	quite	quite	ADV
admet-34	17	3	recently	recently	ADV
admet-34	17	4	,	,	PUNCT
admet-34	17	5	an	an	DET
admet-34	17	6	initiative	initiative	NOUN
admet-34	17	7	of	of	ADP
admet-34	17	8	the	the	DET
admet-34	17	9	pharmaceutical	pharmaceutical	ADJ
admet-34	17	10	research	research	NOUN
admet-34	17	11	and	and	CCONJ
admet-34	17	12	manufacturers	manufacturer	NOUN
admet-34	17	13	of	of	ADP
admet-34	17	14	america	america	PROPN
admet-34	17	15	(	(	PUNCT
admet-34	17	16	phrma	phrma	PROPN
admet-34	17	17	)	)	PUNCT
admet-34	17	18	tried	try	VERB
admet-34	17	19	to	to	PART
admet-34	17	20	evaluate	evaluate	VERB
admet-34	17	21	the	the	DET
admet-34	17	22	reliability	reliability	NOUN
admet-34	17	23	of	of	ADP
admet-34	17	24	predictive	predictive	ADJ
admet-34	17	25	models	model	NOUN
admet-34	17	26	in	in	ADP
admet-34	17	27	terms	term	NOUN
admet-34	17	28	of	of	ADP
admet-34	17	29	of	of	ADP
admet-34	17	30	drug	drug	NOUN
admet-34	17	31	efficacy	efficacy	NOUN
admet-34	17	32	,	,	PUNCT
admet-34	17	33	safety	safety	NOUN
admet-34	17	34	and	and	CCONJ
admet-34	17	35	properties	property	NOUN
admet-34	17	36	estimation	estimation	NOUN
admet-34	17	37	[	[	X
admet-34	17	38	1	1	NUM
admet-34	17	39	-	-	SYM
admet-34	17	40	3	3	NUM
admet-34	17	41	]	]	PUNCT
admet-34	17	42	.	.	PUNCT
admet-34	18	1	for	for	ADP
admet-34	18	2	this	this	DET
admet-34	18	3	purpose	purpose	NOUN
admet-34	18	4	,	,	PUNCT
admet-34	18	5	108	108	NUM
admet-34	18	6	clinical	clinical	ADJ
admet-34	18	7	compounds	compound	NOUN
admet-34	18	8	(	(	PUNCT
admet-34	18	9	22	22	NUM
admet-34	18	10	%	%	NOUN
admet-34	18	11	acids	acid	NOUN
admet-34	18	12	,	,	PUNCT
admet-34	18	13	46	46	NUM
admet-34	18	14	%	%	NOUN
admet-34	18	15	bases	basis	NOUN
admet-34	18	16	,	,	PUNCT
admet-34	18	17	18	18	NUM
admet-34	18	18	%	%	NOUN
admet-34	18	19	zwitterions	zwitterion	NOUN
admet-34	18	20	and	and	CCONJ
admet-34	18	21	14	14	NUM
admet-34	18	22	%	%	NOUN
admet-34	18	23	neutrals	neutral	NOUN
admet-34	18	24	)	)	PUNCT
admet-34	18	25	,	,	PUNCT
admet-34	18	26	supplied	supply	VERB
admet-34	18	27	by	by	ADP
admet-34	18	28	12	12	NUM
admet-34	18	29	phrma	phrma	NOUN
admet-34	18	30	member	member	NOUN
admet-34	18	31	companies	company	NOUN
admet-34	18	32	,	,	PUNCT
admet-34	18	33	have	have	AUX
admet-34	18	34	been	be	AUX
admet-34	18	35	considered	consider	VERB
admet-34	18	36	.	.	PUNCT
admet-34	19	1	the	the	DET
admet-34	19	2	overall	overall	ADJ
admet-34	19	3	goal	goal	NOUN
admet-34	19	4	of	of	ADP
admet-34	19	5	this	this	DET
admet-34	19	6	study	study	NOUN
admet-34	19	7	was	be	AUX
admet-34	19	8	to	to	PART
admet-34	19	9	assess	assess	VERB
admet-34	19	10	the	the	DET
admet-34	19	11	predictability	predictability	NOUN
admet-34	19	12	of	of	ADP
admet-34	19	13	human	human	ADJ
admet-34	19	14	pharmacokinetics	pharmacokinetic	NOUN
admet-34	19	15	(	(	PUNCT
admet-34	19	16	pk	pk	NOUN
admet-34	19	17	)	)	PUNCT
admet-34	19	18	from	from	ADP
admet-34	19	19	preclinical	preclinical	ADJ
admet-34	19	20	data	datum	NOUN
admet-34	19	21	and	and	CCONJ
admet-34	19	22	to	to	PART
admet-34	19	23	provide	provide	VERB
admet-34	19	24	comparisons	comparison	NOUN
admet-34	19	25	of	of	ADP
admet-34	19	26	available	available	ADJ
admet-34	19	27	prediction	prediction	NOUN
admet-34	19	28	methods	method	NOUN
admet-34	19	29	from	from	ADP
admet-34	19	30	literature	literature	NOUN
admet-34	19	31	.	.	PUNCT
admet-34	20	1	in	in	ADP
admet-34	20	2	particular	particular	ADJ
admet-34	20	3	,	,	PUNCT
admet-34	20	4	physiologically	physiologically	ADV
admet-34	20	5	based	base	VERB
admet-34	20	6	pk	pk	NOUN
admet-34	20	7	(	(	PUNCT
admet-34	20	8	pbpk	pbpk	NOUN
admet-34	20	9	)	)	PUNCT
admet-34	20	10	models	model	NOUN
admet-34	20	11	,	,	PUNCT
admet-34	20	12	despite	despite	SCONJ
admet-34	20	13	their	their	PRON
admet-34	20	14	limited	limited	ADJ
admet-34	20	15	application	application	NOUN
admet-34	20	16	in	in	ADP
admet-34	20	17	drug	drug	NOUN
admet-34	20	18	discovery	discovery	NOUN
admet-34	20	19	and	and	CCONJ
admet-34	20	20	development	development	NOUN
admet-34	20	21	,	,	PUNCT
admet-34	20	22	due	due	ADP
admet-34	20	23	to	to	ADP
admet-34	20	24	their	their	PRON
admet-34	20	25	mathematical	mathematical	ADJ
admet-34	20	26	complexity	complexity	NOUN
admet-34	20	27	and	and	CCONJ
admet-34	20	28	requirement	requirement	NOUN
admet-34	20	29	of	of	ADP
admet-34	20	30	many	many	ADJ
admet-34	20	31	experimental	experimental	ADJ
admet-34	20	32	data	datum	NOUN
admet-34	20	33	,	,	PUNCT
admet-34	20	34	have	have	AUX
admet-34	20	35	been	be	AUX
admet-34	20	36	considered	consider	VERB
admet-34	20	37	.	.	PUNCT
admet-34	21	1	indeed	indeed	ADV
admet-34	21	2	,	,	PUNCT
admet-34	21	3	these	these	DET
admet-34	21	4	models	model	NOUN
admet-34	21	5	have	have	VERB
admet-34	21	6	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-34	21	7	admet	admet	PROPN
admet-34	21	8	&	&	CCONJ
admet-34	21	9	dmpk	dmpk	PROPN
admet-34	21	10	2(2	2(2	NUM
admet-34	21	11	)	)	PUNCT
admet-34	21	12	(	(	PUNCT
admet-34	21	13	2014	2014	NUM
admet-34	21	14	)	)	PUNCT
admet-34	21	15	80	80	NUM
admet-34	21	16	-	-	SYM
admet-34	21	17	97	97	NUM
admet-34	21	18	in	in	ADP
admet-34	21	19	vivo	vivo	ADJ
admet-34	21	20	drug	drug	NOUN
admet-34	21	21	release	release	NOUN
admet-34	21	22	and	and	CCONJ
admet-34	21	23	absorption	absorption	NOUN
admet-34	21	24	doi	doi	NOUN
admet-34	21	25	:	:	PUNCT
admet-34	21	26	10.5599	10.5599	NUM
admet-34	21	27	/	/	SYM
admet-34	21	28	admet.2.2.34	admet.2.2.34	PROPN
admet-34	21	29	81	81	NUM
admet-34	21	30	become	become	VERB
admet-34	21	31	more	more	ADV
admet-34	21	32	attractive	attractive	ADJ
admet-34	21	33	for	for	ADP
admet-34	21	34	the	the	DET
admet-34	21	35	prediction	prediction	NOUN
admet-34	21	36	of	of	ADP
admet-34	21	37	human	human	ADJ
admet-34	21	38	pk	pk	NOUN
admet-34	21	39	profiles	profile	NOUN
admet-34	21	40	thanks	thank	NOUN
admet-34	21	41	to	to	ADP
admet-34	21	42	the	the	DET
admet-34	21	43	prediction	prediction	NOUN
admet-34	21	44	of	of	ADP
admet-34	21	45	hepatic	hepatic	ADJ
admet-34	21	46	metabolic	metabolic	NOUN
admet-34	21	47	clearance	clearance	NOUN
admet-34	21	48	and	and	CCONJ
admet-34	21	49	tissue	tissue	NOUN
admet-34	21	50	distribution	distribution	NOUN
admet-34	21	51	from	from	ADP
admet-34	21	52	in	in	ADP
admet-34	21	53	vitro	vitro	X
admet-34	21	54	and	and	CCONJ
admet-34	21	55	in	in	ADP
admet-34	21	56	silico	silico	NOUN
admet-34	21	57	data	datum	NOUN
admet-34	21	58	as	as	ADV
admet-34	21	59	well	well	ADV
admet-34	21	60	as	as	ADP
admet-34	21	61	the	the	DET
admet-34	21	62	advent	advent	NOUN
admet-34	21	63	of	of	ADP
admet-34	21	64	commercially	commercially	ADV
admet-34	21	65	available	available	ADJ
admet-34	21	66	and	and	CCONJ
admet-34	21	67	user	user	NOUN
admet-34	21	68	-	-	PUNCT
admet-34	21	69	friendly	friendly	ADJ
admet-34	21	70	software	software	NOUN
admet-34	21	71	[	[	X
admet-34	21	72	4	4	NUM
admet-34	21	73	]	]	PUNCT
admet-34	21	74	.	.	PUNCT
admet-34	22	1	pbpk	pbpk	PROPN
admet-34	22	2	models	model	NOUN
admet-34	22	3	have	have	AUX
admet-34	22	4	showed	show	VERB
admet-34	22	5	,	,	PUNCT
admet-34	22	6	in	in	ADP
admet-34	22	7	69	69	NUM
admet-34	22	8	%	%	NOUN
admet-34	22	9	of	of	ADP
admet-34	22	10	the	the	DET
admet-34	22	11	cases	case	NOUN
admet-34	22	12	,	,	PUNCT
admet-34	22	13	a	a	DET
admet-34	22	14	medium	medium	NOUN
admet-34	22	15	to	to	ADP
admet-34	22	16	high	high	ADJ
admet-34	22	17	degree	degree	NOUN
admet-34	22	18	of	of	ADP
admet-34	22	19	accuracy	accuracy	NOUN
admet-34	22	20	in	in	ADP
admet-34	22	21	simulating	simulate	VERB
admet-34	22	22	the	the	DET
admet-34	22	23	time	time	NOUN
admet-34	22	24	course	course	NOUN
admet-34	22	25	of	of	ADP
admet-34	22	26	the	the	DET
admet-34	22	27	drug	drug	NOUN
admet-34	22	28	plasma	plasma	NOUN
admet-34	22	29	concentration	concentration	NOUN
admet-34	22	30	in	in	ADP
admet-34	22	31	human	human	ADJ
admet-34	22	32	following	follow	VERB
admet-34	22	33	intravenous	intravenous	ADJ
admet-34	22	34	administration	administration	NOUN
admet-34	22	35	.	.	PUNCT
admet-34	23	1	on	on	ADP
admet-34	23	2	the	the	DET
admet-34	23	3	contrary	contrary	NOUN
admet-34	23	4	,	,	PUNCT
admet-34	23	5	the	the	DET
admet-34	23	6	accuracy	accuracy	NOUN
admet-34	23	7	decreases	decrease	VERB
admet-34	23	8	to	to	ADP
admet-34	23	9	23	23	NUM
admet-34	23	10	%	%	NOUN
admet-34	23	11	in	in	ADP
admet-34	23	12	case	case	NOUN
admet-34	23	13	of	of	ADP
admet-34	23	14	oral	oral	ADJ
admet-34	23	15	administration	administration	NOUN
admet-34	23	16	[	[	X
admet-34	23	17	5	5	NUM
admet-34	23	18	]	]	PUNCT
admet-34	23	19	.	.	PUNCT
admet-34	24	1	accordingly	accordingly	ADV
admet-34	24	2	,	,	PUNCT
admet-34	24	3	the	the	DET
admet-34	24	4	authors	author	NOUN
admet-34	24	5	of	of	ADP
admet-34	24	6	this	this	DET
admet-34	24	7	study	study	NOUN
admet-34	24	8	concluded	conclude	VERB
admet-34	24	9	that	that	SCONJ
admet-34	24	10	i	i	PRON
admet-34	24	11	)	)	PUNCT
admet-34	24	12	pbpk	pbpk	PROPN
admet-34	24	13	models	model	NOUN
admet-34	24	14	can	can	AUX
admet-34	24	15	be	be	AUX
admet-34	24	16	a	a	DET
admet-34	24	17	useful	useful	ADJ
admet-34	24	18	basis	basis	NOUN
admet-34	24	19	for	for	ADP
admet-34	24	20	a	a	DET
admet-34	24	21	more	more	ADV
admet-34	24	22	rational	rational	ADJ
admet-34	24	23	selection	selection	NOUN
admet-34	24	24	of	of	ADP
admet-34	24	25	first	first	ADJ
admet-34	24	26	-	-	PUNCT
admet-34	24	27	in	in	ADP
admet-34	24	28	-	-	PUNCT
admet-34	24	29	human	human	ADJ
admet-34	24	30	phase	phase	NOUN
admet-34	24	31	dose	dose	VERB
admet-34	24	32	ranges	range	NOUN
admet-34	24	33	and	and	CCONJ
admet-34	24	34	that	that	DET
admet-34	24	35	ii	ii	NOUN
admet-34	24	36	)	)	PUNCT
admet-34	24	37	there	there	PRON
admet-34	24	38	is	be	VERB
admet-34	24	39	a	a	DET
admet-34	24	40	need	need	NOUN
admet-34	24	41	for	for	ADP
admet-34	24	42	better	well	ADJ
admet-34	24	43	predictions	prediction	NOUN
admet-34	24	44	of	of	ADP
admet-34	24	45	human	human	ADJ
admet-34	24	46	pharmacokinetics	pharmacokinetic	NOUN
admet-34	24	47	following	follow	VERB
admet-34	24	48	oral	oral	ADJ
admet-34	24	49	administration	administration	NOUN
admet-34	24	50	.	.	PUNCT
admet-34	25	1	indeed	indeed	ADV
admet-34	25	2	,	,	PUNCT
admet-34	25	3	predicting	predict	VERB
admet-34	25	4	the	the	DET
admet-34	25	5	time	time	NOUN
admet-34	25	6	course	course	NOUN
admet-34	25	7	of	of	ADP
admet-34	25	8	drug	drug	NOUN
admet-34	25	9	concentration	concentration	NOUN
admet-34	25	10	in	in	ADP
admet-34	25	11	plasma	plasma	NOUN
admet-34	25	12	/	/	SYM
admet-34	25	13	blood	blood	NOUN
admet-34	25	14	following	follow	VERB
admet-34	25	15	oral	oral	ADJ
admet-34	25	16	administration	administration	NOUN
admet-34	25	17	presents	present	VERB
admet-34	25	18	the	the	DET
admet-34	25	19	not	not	PART
admet-34	25	20	negligible	negligible	ADJ
admet-34	25	21	difficulty	difficulty	NOUN
admet-34	25	22	of	of	ADP
admet-34	25	23	simulating	simulate	VERB
admet-34	25	24	both	both	CCONJ
admet-34	25	25	the	the	DET
admet-34	25	26	delivery	delivery	NOUN
admet-34	25	27	and	and	CCONJ
admet-34	25	28	the	the	DET
admet-34	25	29	absorption	absorption	NOUN
admet-34	25	30	stages	stage	NOUN
admet-34	25	31	which	which	PRON
admet-34	25	32	is	be	AUX
admet-34	25	33	obviously	obviously	ADV
admet-34	25	34	not	not	PART
admet-34	25	35	needed	need	VERB
admet-34	25	36	with	with	ADP
admet-34	25	37	intravenous	intravenous	ADJ
admet-34	25	38	administration	administration	NOUN
admet-34	25	39	.	.	PUNCT
admet-34	26	1	when	when	SCONJ
admet-34	26	2	efforts	effort	NOUN
admet-34	26	3	have	have	AUX
admet-34	26	4	been	be	AUX
admet-34	26	5	focused	focus	VERB
admet-34	26	6	on	on	ADP
admet-34	26	7	taking	take	VERB
admet-34	26	8	into	into	ADP
admet-34	26	9	account	account	NOUN
admet-34	26	10	one	one	NUM
admet-34	26	11	of	of	ADP
admet-34	26	12	these	these	DET
admet-34	26	13	two	two	NUM
admet-34	26	14	stages	stage	NOUN
admet-34	26	15	,	,	PUNCT
admet-34	26	16	they	they	PRON
admet-34	26	17	were	be	AUX
admet-34	26	18	directed	direct	VERB
admet-34	26	19	to	to	ADP
admet-34	26	20	the	the	DET
admet-34	26	21	absorption	absorption	NOUN
admet-34	26	22	[	[	X
admet-34	26	23	6	6	NUM
admet-34	26	24	]	]	PUNCT
admet-34	26	25	,	,	PUNCT
admet-34	26	26	neglecting	neglect	VERB
admet-34	26	27	the	the	DET
admet-34	26	28	delivery	delivery	NOUN
admet-34	26	29	stage	stage	NOUN
admet-34	26	30	.	.	PUNCT
admet-34	27	1	as	as	ADP
admet-34	27	2	a	a	DET
admet-34	27	3	matter	matter	NOUN
admet-34	27	4	of	of	ADP
admet-34	27	5	fact	fact	NOUN
admet-34	27	6	,	,	PUNCT
admet-34	27	7	both	both	CCONJ
admet-34	27	8	the	the	DET
admet-34	27	9	phrma	phrma	NOUN
admet-34	27	10	study	study	NOUN
admet-34	27	11	and	and	CCONJ
admet-34	27	12	common	common	ADJ
admet-34	27	13	commercial	commercial	ADJ
admet-34	27	14	software	software	NOUN
admet-34	27	15	consider	consider	VERB
admet-34	27	16	the	the	DET
admet-34	27	17	release	release	NOUN
admet-34	27	18	stage	stage	NOUN
admet-34	27	19	either	either	CCONJ
admet-34	27	20	by	by	ADP
admet-34	27	21	assuming	assume	VERB
admet-34	27	22	a	a	DET
admet-34	27	23	fixed	fix	VERB
admet-34	27	24	release	release	NOUN
admet-34	27	25	kinetics	kinetic	NOUN
admet-34	27	26	or	or	CCONJ
admet-34	27	27	by	by	ADP
admet-34	27	28	providing	provide	VERB
admet-34	27	29	the	the	DET
admet-34	27	30	model	model	NOUN
admet-34	27	31	with	with	ADP
admet-34	27	32	an	an	DET
admet-34	27	33	in	in	ADP
admet-34	27	34	vitro	vitro	X
admet-34	27	35	release	release	NOUN
admet-34	27	36	profile	profile	NOUN
admet-34	27	37	assumed	assume	VERB
admet-34	27	38	to	to	PART
admet-34	27	39	be	be	AUX
admet-34	27	40	representative	representative	ADJ
admet-34	27	41	of	of	ADP
admet-34	27	42	in	in	ADP
admet-34	27	43	vivo	vivo	ADJ
admet-34	27	44	release	release	NOUN
admet-34	27	45	[	[	X
admet-34	27	46	5	5	NUM
admet-34	27	47	]	]	PUNCT
admet-34	27	48	.	.	PUNCT
admet-34	28	1	in	in	ADP
admet-34	28	2	this	this	DET
admet-34	28	3	light	light	NOUN
admet-34	28	4	and	and	CCONJ
admet-34	28	5	considering	consider	VERB
admet-34	28	6	that	that	DET
admet-34	28	7	oral	oral	ADJ
admet-34	28	8	administration	administration	NOUN
admet-34	28	9	is	be	AUX
admet-34	28	10	by	by	ADP
admet-34	28	11	far	far	ADV
admet-34	28	12	the	the	DET
admet-34	28	13	most	most	ADV
admet-34	28	14	common	common	ADJ
admet-34	28	15	route	route	NOUN
admet-34	28	16	of	of	ADP
admet-34	28	17	drug	drug	NOUN
admet-34	28	18	administration	administration	NOUN
admet-34	28	19	[	[	X
admet-34	28	20	5	5	NUM
admet-34	28	21	]	]	PUNCT
admet-34	28	22	,	,	PUNCT
admet-34	28	23	we	we	PRON
admet-34	28	24	believe	believe	VERB
admet-34	28	25	it	it	PRON
admet-34	28	26	is	be	AUX
admet-34	28	27	worth	worth	ADJ
admet-34	28	28	working	work	VERB
admet-34	28	29	on	on	ADP
admet-34	28	30	the	the	DET
admet-34	28	31	improvement	improvement	NOUN
admet-34	28	32	of	of	ADP
admet-34	28	33	pbpk	pbpk	NOUN
admet-34	28	34	models	model	NOUN
admet-34	28	35	devoted	devote	VERB
admet-34	28	36	to	to	PART
admet-34	28	37	simulate	simulate	VERB
admet-34	28	38	pk	pk	NOUN
admet-34	28	39	following	follow	VERB
admet-34	28	40	oral	oral	ADJ
admet-34	28	41	administration	administration	NOUN
admet-34	28	42	.	.	PUNCT
admet-34	29	1	in	in	ADP
admet-34	29	2	addition	addition	NOUN
admet-34	29	3	,	,	PUNCT
admet-34	29	4	we	we	PRON
admet-34	29	5	are	be	AUX
admet-34	29	6	convinced	convince	VERB
admet-34	29	7	that	that	SCONJ
admet-34	29	8	the	the	DET
admet-34	29	9	new	new	ADJ
admet-34	29	10	challenge	challenge	NOUN
admet-34	29	11	in	in	ADP
admet-34	29	12	the	the	DET
admet-34	29	13	drug	drug	NOUN
admet-34	29	14	delivery	delivery	NOUN
admet-34	29	15	field	field	NOUN
admet-34	29	16	,	,	PUNCT
admet-34	29	17	for	for	ADP
admet-34	29	18	mathematical	mathematical	ADJ
admet-34	29	19	modelling	modelling	NOUN
admet-34	29	20	,	,	PUNCT
admet-34	29	21	is	be	AUX
admet-34	29	22	to	to	PART
admet-34	29	23	combine	combine	VERB
admet-34	29	24	of	of	ADP
admet-34	29	25	mechanistic	mechanistic	ADJ
admet-34	29	26	theories	theory	NOUN
admet-34	29	27	able	able	ADJ
admet-34	29	28	to	to	PART
admet-34	29	29	realistically	realistically	ADV
admet-34	29	30	describe	describe	VERB
admet-34	29	31	the	the	DET
admet-34	29	32	simultaneous	simultaneous	ADJ
admet-34	29	33	processes	process	NOUN
admet-34	29	34	of	of	ADP
admet-34	29	35	drug	drug	NOUN
admet-34	29	36	release	release	NOUN
admet-34	29	37	and	and	CCONJ
admet-34	29	38	the	the	DET
admet-34	29	39	subsequent	subsequent	ADJ
admet-34	29	40	adme	adme	NOUN
admet-34	29	41	processes	process	NOUN
admet-34	29	42	within	within	ADP
admet-34	29	43	the	the	DET
admet-34	29	44	human	human	ADJ
admet-34	29	45	body	body	NOUN
admet-34	29	46	[	[	X
admet-34	29	47	7,8	7,8	NUM
admet-34	29	48	]	]	PUNCT
admet-34	29	49	.	.	PUNCT
admet-34	30	1	indeed	indeed	ADV
admet-34	30	2	,	,	PUNCT
admet-34	30	3	this	this	DET
admet-34	30	4	step	step	NOUN
admet-34	30	5	is	be	AUX
admet-34	30	6	a	a	DET
admet-34	30	7	fundamental	fundamental	ADJ
admet-34	30	8	prerequisite	prerequisite	NOUN
admet-34	30	9	to	to	PART
admet-34	30	10	get	get	VERB
admet-34	30	11	the	the	DET
admet-34	30	12	final	final	ADJ
admet-34	30	13	objective	objective	NOUN
admet-34	30	14	of	of	ADP
admet-34	30	15	building	build	VERB
admet-34	30	16	up	up	ADP
admet-34	30	17	a	a	DET
admet-34	30	18	mathematical	mathematical	ADJ
admet-34	30	19	model	model	NOUN
admet-34	30	20	able	able	ADJ
admet-34	30	21	to	to	PART
admet-34	30	22	predict	predict	VERB
admet-34	30	23	pharmacodynamics	pharmacodynamic	NOUN
admet-34	30	24	,	,	PUNCT
admet-34	30	25	i.e.	i.e.	X
admet-34	30	26	the	the	DET
admet-34	30	27	clinical	clinical	ADJ
admet-34	30	28	effect	effect	NOUN
admet-34	30	29	of	of	ADP
admet-34	30	30	a	a	DET
admet-34	30	31	drug	drug	NOUN
admet-34	30	32	released	release	VERB
admet-34	30	33	from	from	ADP
admet-34	30	34	a	a	DET
admet-34	30	35	specific	specific	ADJ
admet-34	30	36	delivery	delivery	NOUN
admet-34	30	37	system	system	NOUN
admet-34	30	38	[	[	X
admet-34	30	39	9	9	NUM
admet-34	30	40	]	]	PUNCT
admet-34	30	41	.	.	PUNCT
admet-34	31	1	nowadays	nowadays	ADV
admet-34	31	2	,	,	PUNCT
admet-34	31	3	many	many	ADJ
admet-34	31	4	powerful	powerful	ADJ
admet-34	31	5	commercial	commercial	ADJ
admet-34	31	6	software	software	NOUN
admet-34	31	7	exist	exist	VERB
admet-34	31	8	for	for	ADP
admet-34	31	9	the	the	DET
admet-34	31	10	simulation	simulation	NOUN
admet-34	31	11	of	of	ADP
admet-34	31	12	pk	pk	PROPN
admet-34	31	13	phenomena	phenomenon	NOUN
admet-34	31	14	.	.	PUNCT
admet-34	32	1	among	among	ADP
admet-34	32	2	them	they	PRON
admet-34	32	3	,	,	PUNCT
admet-34	32	4	simcyp	simcyp	ADV
admet-34	32	5	,	,	PUNCT
admet-34	32	6	gastroplus	gastroplus	NOUN
admet-34	32	7	and	and	CCONJ
admet-34	32	8	pk	pk	NOUN
admet-34	32	9	-	-	ADJ
admet-34	32	10	sim	sim	NOUN
admet-34	32	11	can	can	AUX
admet-34	32	12	be	be	AUX
admet-34	32	13	cited	cite	VERB
admet-34	32	14	.	.	PUNCT
admet-34	33	1	these	these	DET
admet-34	33	2	commercial	commercial	ADJ
admet-34	33	3	pbpk	pbpk	NOUN
admet-34	33	4	models	model	NOUN
admet-34	33	5	combine	combine	VERB
admet-34	33	6	a	a	DET
admet-34	33	7	variety	variety	NOUN
admet-34	33	8	of	of	ADP
admet-34	33	9	functions	function	NOUN
admet-34	33	10	for	for	ADP
admet-34	33	11	defining	define	VERB
admet-34	33	12	release	release	NOUN
admet-34	33	13	from	from	ADP
admet-34	33	14	oral	oral	ADJ
admet-34	33	15	formulations	formulation	NOUN
admet-34	33	16	with	with	ADP
admet-34	33	17	sophisticated	sophisticated	ADJ
admet-34	33	18	models	model	NOUN
admet-34	33	19	for	for	ADP
admet-34	33	20	the	the	DET
admet-34	33	21	description	description	NOUN
admet-34	33	22	of	of	ADP
admet-34	33	23	adme	adme	NOUN
admet-34	33	24	processes	process	NOUN
admet-34	33	25	.	.	PUNCT
admet-34	34	1	in	in	ADP
admet-34	34	2	particular	particular	ADJ
admet-34	34	3	,	,	PUNCT
admet-34	34	4	simcyp	simcyp	NOUN
admet-34	34	5	is	be	AUX
admet-34	34	6	able	able	ADJ
admet-34	34	7	to	to	PART
admet-34	34	8	account	account	VERB
admet-34	34	9	for	for	ADP
admet-34	34	10	population	population	NOUN
admet-34	34	11	variability	variability	NOUN
admet-34	34	12	of	of	ADP
admet-34	34	13	parameters	parameter	NOUN
admet-34	34	14	and	and	CCONJ
admet-34	34	15	their	their	PRON
admet-34	34	16	covariation	covariation	NOUN
admet-34	34	17	where	where	SCONJ
admet-34	34	18	known	know	VERB
admet-34	34	19	.	.	PUNCT
admet-34	35	1	our	our	PRON
admet-34	35	2	mathematical	mathematical	ADJ
admet-34	35	3	model	model	NOUN
admet-34	35	4	,	,	PUNCT
admet-34	35	5	on	on	ADP
admet-34	35	6	the	the	DET
admet-34	35	7	contrary	contrary	NOUN
admet-34	35	8	,	,	PUNCT
admet-34	35	9	tries	try	VERB
admet-34	35	10	to	to	PART
admet-34	35	11	establish	establish	VERB
admet-34	35	12	a	a	DET
admet-34	35	13	deep	deep	ADJ
admet-34	35	14	connection	connection	NOUN
admet-34	35	15	between	between	ADP
admet-34	35	16	the	the	DET
admet-34	35	17	adme	adme	NOUN
admet-34	35	18	phenomena	phenomenon	NOUN
admet-34	35	19	,	,	PUNCT
admet-34	35	20	described	describe	VERB
admet-34	35	21	by	by	ADP
admet-34	35	22	a	a	DET
admet-34	35	23	recently	recently	ADV
admet-34	35	24	developed	develop	VERB
admet-34	35	25	simple	simple	ADJ
admet-34	35	26	pbpk	pbpk	ADJ
admet-34	35	27	model	model	NOUN
admet-34	35	28	[	[	X
admet-34	35	29	10	10	NUM
admet-34	35	30	]	]	PUNCT
admet-34	35	31	,	,	PUNCT
admet-34	35	32	and	and	CCONJ
admet-34	35	33	the	the	DET
admet-34	35	34	drug	drug	NOUN
admet-34	35	35	delivery	delivery	NOUN
admet-34	35	36	step	step	NOUN
admet-34	35	37	,	,	PUNCT
admet-34	35	38	described	describe	VERB
admet-34	35	39	by	by	ADP
admet-34	35	40	a	a	DET
admet-34	35	41	model	model	NOUN
admet-34	36	1	[	[	X
admet-34	36	2	11,12	11,12	NOUN
admet-34	36	3	]	]	PUNCT
admet-34	36	4	that	that	PRON
admet-34	36	5	proved	prove	VERB
admet-34	36	6	to	to	PART
admet-34	36	7	be	be	AUX
admet-34	36	8	reliable	reliable	ADJ
admet-34	36	9	.	.	PUNCT
admet-34	37	1	in	in	ADP
admet-34	37	2	particular	particular	ADJ
admet-34	37	3	,	,	PUNCT
admet-34	37	4	the	the	DET
admet-34	37	5	considered	consider	VERB
admet-34	37	6	delivery	delivery	NOUN
admet-34	37	7	system	system	NOUN
admet-34	37	8	consists	consist	VERB
admet-34	37	9	of	of	ADP
admet-34	37	10	an	an	DET
admet-34	37	11	ensemble	ensemble	NOUN
admet-34	37	12	of	of	ADP
admet-34	37	13	non	non	ADJ
admet-34	37	14	-	-	ADJ
admet-34	37	15	eroding	eroding	ADJ
admet-34	37	16	poly	poly	NOUN
admet-34	37	17	-	-	PUNCT
admet-34	37	18	dispersed	disperse	VERB
admet-34	37	19	polymeric	polymeric	ADJ
admet-34	37	20	particles	particle	NOUN
admet-34	37	21	hosting	host	VERB
admet-34	37	22	the	the	DET
admet-34	37	23	drug	drug	NOUN
admet-34	37	24	inside	inside	ADP
admet-34	37	25	polymeric	polymeric	ADJ
admet-34	37	26	meshes	mesh	NOUN
admet-34	37	27	.	.	PUNCT
admet-34	38	1	particulate	particulate	NOUN
admet-34	38	2	systems	system	NOUN
admet-34	38	3	,	,	PUNCT
admet-34	38	4	indeed	indeed	ADV
admet-34	38	5	,	,	PUNCT
admet-34	38	6	present	present	ADJ
admet-34	38	7	remarkable	remarkable	ADJ
admet-34	38	8	advantages	advantage	NOUN
admet-34	38	9	over	over	ADP
admet-34	38	10	the	the	DET
admet-34	38	11	single	single	ADJ
admet-34	38	12	unit	unit	NOUN
admet-34	38	13	devices	device	NOUN
admet-34	38	14	including	include	VERB
admet-34	38	15	easier	easy	ADJ
admet-34	38	16	dispersion	dispersion	NOUN
admet-34	38	17	within	within	ADP
admet-34	38	18	the	the	DET
admet-34	38	19	stomach	stomach	NOUN
admet-34	38	20	that	that	PRON
admet-34	38	21	can	can	AUX
admet-34	38	22	result	result	VERB
admet-34	38	23	in	in	ADP
admet-34	38	24	an	an	DET
admet-34	38	25	appreciable	appreciable	ADJ
admet-34	38	26	reduction	reduction	NOUN
admet-34	38	27	of	of	ADP
admet-34	38	28	local	local	ADJ
admet-34	38	29	drug	drug	NOUN
admet-34	38	30	concentration	concentration	NOUN
admet-34	38	31	,	,	PUNCT
admet-34	38	32	and	and	CCONJ
admet-34	38	33	reduction	reduction	NOUN
admet-34	38	34	of	of	ADP
admet-34	38	35	the	the	DET
admet-34	38	36	insurgence	insurgence	NOUN
admet-34	38	37	of	of	ADP
admet-34	38	38	gastric	gastric	ADJ
admet-34	38	39	irritation	irritation	NOUN
admet-34	39	1	[	[	X
admet-34	39	2	13	13	NUM
admet-34	39	3	]	]	PUNCT
admet-34	39	4	.	.	PUNCT
admet-34	40	1	moreover	moreover	ADV
admet-34	40	2	,	,	PUNCT
admet-34	40	3	particulate	particulate	NOUN
admet-34	40	4	systems	system	NOUN
admet-34	40	5	are	be	AUX
admet-34	40	6	very	very	ADV
admet-34	40	7	versatile	versatile	ADJ
admet-34	40	8	,	,	PUNCT
admet-34	40	9	one	one	NUM
admet-34	40	10	more	more	ADJ
admet-34	40	11	reason	reason	NOUN
admet-34	40	12	for	for	ADP
admet-34	40	13	their	their	PRON
admet-34	40	14	wide	wide	ADJ
admet-34	40	15	use	use	NOUN
admet-34	40	16	.	.	PUNCT
admet-34	41	1	mathematical	mathematical	ADJ
admet-34	41	2	model	model	NOUN
admet-34	41	3	pbpk	pbpk	PROPN
admet-34	41	4	model	model	NOUN
admet-34	41	5	the	the	DET
admet-34	41	6	mathematical	mathematical	ADJ
admet-34	41	7	representation	representation	NOUN
admet-34	41	8	of	of	ADP
admet-34	41	9	the	the	DET
admet-34	41	10	human	human	ADJ
admet-34	41	11	body	body	NOUN
admet-34	41	12	is	be	AUX
admet-34	41	13	essentially	essentially	ADV
admet-34	41	14	based	base	VERB
admet-34	41	15	on	on	ADP
admet-34	41	16	the	the	DET
admet-34	41	17	pbpk	pbpk	PROPN
admet-34	41	18	model	model	NOUN
admet-34	41	19	presented	present	VERB
admet-34	41	20	by	by	ADP
admet-34	41	21	di	di	X
admet-34	41	22	muria	muria	PROPN
admet-34	41	23	and	and	CCONJ
admet-34	41	24	co	co	NOUN
admet-34	41	25	-	-	NOUN
admet-34	41	26	workers	worker	NOUN
admet-34	41	27	[	[	X
admet-34	41	28	10	10	NUM
admet-34	41	29	]	]	PUNCT
admet-34	41	30	.	.	PUNCT
admet-34	42	1	the	the	DET
admet-34	42	2	gastrointestinal	gastrointestinal	ADJ
admet-34	42	3	(	(	PUNCT
admet-34	42	4	gi	gi	NOUN
admet-34	42	5	)	)	PUNCT
admet-34	42	6	tract	tract	NOUN
admet-34	42	7	is	be	AUX
admet-34	42	8	described	describe	VERB
admet-34	42	9	by	by	ADP
admet-34	42	10	a	a	DET
admet-34	42	11	continuous	continuous	ADJ
admet-34	42	12	hollow	hollow	ADJ
admet-34	42	13	cylinder	cylinder	NOUN
admet-34	42	14	subdivided	subdivide	VERB
admet-34	42	15	into	into	ADP
admet-34	42	16	three	three	NUM
admet-34	42	17	zones	zone	NOUN
admet-34	42	18	:	:	PUNCT
admet-34	42	19	the	the	DET
admet-34	42	20	gastric	gastric	ADJ
admet-34	42	21	lumen	luman	NOUN
admet-34	42	22	(	(	PUNCT
admet-34	42	23	gl	gl	X
admet-34	42	24	)	)	PUNCT
admet-34	42	25	the	the	DET
admet-34	42	26	small	small	ADJ
admet-34	42	27	intestine	intestine	NOUN
admet-34	42	28	lumen	luman	NOUN
admet-34	42	29	(	(	PUNCT
admet-34	42	30	sil	sil	PROPN
admet-34	42	31	)	)	PUNCT
admet-34	42	32	and	and	CCONJ
admet-34	42	33	the	the	DET
admet-34	42	34	large	large	ADJ
admet-34	42	35	intestine	intestine	NOUN
admet-34	42	36	lumen	luman	NOUN
admet-34	42	37	(	(	PUNCT
admet-34	42	38	lil	lil	PROPN
admet-34	42	39	)	)	PUNCT
admet-34	42	40	(	(	PUNCT
admet-34	42	41	see	see	VERB
admet-34	42	42	figure	figure	NOUN
admet-34	42	43	1	1	NUM
admet-34	42	44	)	)	PUNCT
admet-34	42	45	.	.	PUNCT
admet-34	43	1	the	the	DET
admet-34	43	2	different	different	ADJ
admet-34	43	3	physiological	physiological	ADJ
admet-34	43	4	and	and	CCONJ
admet-34	43	5	morphological	morphological	ADJ
admet-34	43	6	conditions	condition	NOUN
admet-34	43	7	(	(	PUNCT
admet-34	43	8	for	for	ADP
admet-34	43	9	example	example	NOUN
admet-34	43	10	ph	ph	ADJ
admet-34	43	11	and	and	CCONJ
admet-34	43	12	internal	internal	ADJ
admet-34	43	13	radius	radius	NOUN
admet-34	43	14	)	)	PUNCT
admet-34	43	15	in	in	ADP
admet-34	43	16	the	the	DET
admet-34	43	17	gi	gi	NOUN
admet-34	43	18	tract	tract	NOUN
admet-34	43	19	,	,	PUNCT
admet-34	43	20	account	account	VERB
admet-34	43	21	for	for	ADP
admet-34	43	22	different	different	ADJ
admet-34	43	23	permeability	permeability	NOUN
admet-34	43	24	(	(	PUNCT
admet-34	43	25	pgl	pgl	NOUN
admet-34	43	26	,	,	PUNCT
admet-34	43	27	psil	psil	NOUN
admet-34	43	28	and	and	CCONJ
admet-34	43	29	plil	plil	NOUN
admet-34	43	30	,	,	PUNCT
admet-34	43	31	respectively	respectively	ADV
admet-34	43	32	)	)	PUNCT
admet-34	43	33	,	,	PUNCT
admet-34	43	34	drug	drug	NOUN
admet-34	43	35	solubility	solubility	NOUN
admet-34	43	36	(	(	PUNCT
admet-34	43	37	csgl	csgl	ADJ
admet-34	43	38	,	,	PUNCT
admet-34	43	39	cssil	cssil	NOUN
admet-34	43	40	and	and	CCONJ
admet-34	43	41	cslil	cslil	NOUN
admet-34	43	42	,	,	PUNCT
admet-34	43	43	respectively	respectively	ADV
admet-34	43	44	)	)	PUNCT
admet-34	43	45	and	and	CCONJ
admet-34	43	46	internal	internal	ADJ
admet-34	43	47	radius	radius	NOUN
admet-34	43	48	(	(	PUNCT
admet-34	43	49	i	i	PRON
admet-34	43	50	glr	glr	PROPN
admet-34	43	51	,	,	PUNCT
admet-34	43	52	i	i	PRON
admet-34	43	53	silr	silr	PROPN
admet-34	44	1	and	and	CCONJ
admet-34	44	2	i	i	PRON
admet-34	44	3	lilr	lilr	VERB
admet-34	44	4	,	,	PUNCT
admet-34	44	5	respectively	respectively	ADV
admet-34	44	6	)	)	PUNCT
admet-34	44	7	for	for	ADP
admet-34	44	8	each	each	DET
admet-34	44	9	zone	zone	NOUN
admet-34	44	10	.	.	PUNCT
admet-34	45	1	the	the	DET
admet-34	45	2	gi	gi	PROPN
admet-34	45	3	tract	tract	NOUN
admet-34	45	4	is	be	AUX
admet-34	45	5	crossed	cross	VERB
admet-34	45	6	by	by	ADP
admet-34	45	7	the	the	DET
admet-34	45	8	release	release	NOUN
admet-34	45	9	environment	environment	NOUN
admet-34	45	10	,	,	PUNCT
admet-34	45	11	an	an	DET
admet-34	45	12	aqueous	aqueous	ADJ
admet-34	45	13	volume	volume	NOUN
admet-34	45	14	(	(	PUNCT
admet-34	45	15	vr	vr	PROPN
admet-34	45	16	)	)	PUNCT
admet-34	45	17	,	,	PUNCT
admet-34	45	18	containing	contain	VERB
admet-34	45	19	the	the	DET
admet-34	45	20	delivery	delivery	NOUN
admet-34	45	21	system	system	NOUN
admet-34	45	22	del	del	PROPN
admet-34	45	23	cont	cont	NOUN
admet-34	45	24	et	et	PROPN
admet-34	45	25	al	al	PROPN
admet-34	45	26	.	.	PROPN
admet-34	45	27	admet	admet	PROPN
admet-34	45	28	&	&	CCONJ
admet-34	45	29	dmpk	dmpk	PROPN
admet-34	45	30	2(2	2(2	NUM
admet-34	45	31	)	)	PUNCT
admet-34	45	32	(	(	PUNCT
admet-34	45	33	2014	2014	NUM
admet-34	45	34	)	)	PUNCT
admet-34	45	35	80	80	NUM
admet-34	45	36	-	-	SYM
admet-34	45	37	97	97	NUM
admet-34	45	38	82	82	NUM
admet-34	45	39	(	(	PUNCT
admet-34	45	40	an	an	DET
admet-34	45	41	ensemble	ensemble	NOUN
admet-34	45	42	of	of	ADP
admet-34	45	43	drug	drug	NOUN
admet-34	45	44	loaded	load	VERB
admet-34	45	45	,	,	PUNCT
admet-34	45	46	non	non	ADJ
admet-34	45	47	-	-	ADJ
admet-34	45	48	eroding	eroding	ADJ
admet-34	45	49	,	,	PUNCT
admet-34	45	50	poly	poly	ADJ
admet-34	45	51	-	-	PUNCT
admet-34	45	52	dispersed	disperse	VERB
admet-34	45	53	polymeric	polymeric	ADJ
admet-34	45	54	particles	particle	NOUN
admet-34	45	55	)	)	PUNCT
admet-34	45	56	,	,	PUNCT
admet-34	45	57	that	that	SCONJ
admet-34	45	58	,	,	PUNCT
admet-34	45	59	due	due	ADP
admet-34	45	60	to	to	ADP
admet-34	45	61	peristaltic	peristaltic	ADJ
admet-34	45	62	movements	movement	NOUN
admet-34	45	63	,	,	PUNCT
admet-34	45	64	flows	flow	VERB
admet-34	45	65	downwards	downwards	ADV
admet-34	45	66	from	from	ADP
admet-34	45	67	the	the	DET
admet-34	45	68	gl	gl	NOUN
admet-34	45	69	to	to	ADP
admet-34	45	70	the	the	DET
admet-34	45	71	sil	sil	PROPN
admet-34	45	72	and	and	CCONJ
admet-34	45	73	eventually	eventually	ADV
admet-34	45	74	to	to	ADP
admet-34	45	75	the	the	DET
admet-34	45	76	lil	lil	PROPN
admet-34	45	77	.	.	PUNCT
admet-34	46	1	for	for	ADP
admet-34	46	2	modelling	model	VERB
admet-34	46	3	purposes	purpose	NOUN
admet-34	46	4	,	,	PUNCT
admet-34	46	5	it	it	PRON
admet-34	46	6	is	be	AUX
admet-34	46	7	assumed	assume	VERB
admet-34	46	8	that	that	SCONJ
admet-34	46	9	the	the	DET
admet-34	46	10	release	release	NOUN
admet-34	46	11	environment	environment	NOUN
admet-34	46	12	shape	shape	NOUN
admet-34	46	13	is	be	AUX
admet-34	46	14	that	that	PRON
admet-34	46	15	of	of	ADP
admet-34	46	16	a	a	DET
admet-34	46	17	hollow	hollow	ADJ
admet-34	46	18	cylinder	cylinder	NOUN
admet-34	46	19	whose	whose	DET
admet-34	46	20	external	external	ADJ
admet-34	46	21	radius	radius	NOUN
admet-34	46	22	coincides	coincide	VERB
admet-34	46	23	with	with	ADP
admet-34	46	24	i	i	PRON
admet-34	46	25	glr	glr	PROPN
admet-34	46	26	,	,	PUNCT
admet-34	46	27	i	i	PRON
admet-34	46	28	silr	silr	PROPN
admet-34	46	29	or	or	CCONJ
admet-34	46	30	i	i	PRON
admet-34	46	31	lilr	lilr	VERB
admet-34	46	32	,	,	PUNCT
admet-34	46	33	while	while	SCONJ
admet-34	46	34	the	the	DET
admet-34	46	35	internal	internal	ADJ
admet-34	46	36	radius	radius	NOUN
admet-34	46	37	(	(	PUNCT
admet-34	46	38	ri	ri	NOUN
admet-34	46	39	)	)	PUNCT
admet-34	46	40	can	can	AUX
admet-34	46	41	span	span	VERB
admet-34	46	42	from	from	ADP
admet-34	46	43	zero	zero	NUM
admet-34	46	44	to	to	ADP
admet-34	46	45	i	i	PRON
admet-34	46	46	glr	glr	PROPN
admet-34	46	47	,	,	PUNCT
admet-34	47	1	i	i	PRON
admet-34	47	2	silr	silr	PROPN
admet-34	47	3	or	or	CCONJ
admet-34	47	4	i	i	PRON
admet-34	47	5	lilr	lilr	VERB
admet-34	47	6	.	.	PUNCT
admet-34	48	1	figure	figure	VERB
admet-34	48	2	1	1	NUM
admet-34	48	3	.	.	PUNCT
admet-34	48	4	schematic	schematic	ADJ
admet-34	48	5	representation	representation	NOUN
admet-34	48	6	of	of	ADP
admet-34	48	7	the	the	DET
admet-34	48	8	physiologically	physiologically	ADV
admet-34	48	9	-	-	PUNCT
admet-34	48	10	oriented	orient	VERB
admet-34	48	11	mathematical	mathematical	ADJ
admet-34	48	12	model	model	NOUN
admet-34	48	13	.	.	PUNCT
admet-34	49	1	the	the	DET
admet-34	49	2	release	release	NOUN
admet-34	49	3	environment	environment	NOUN
admet-34	49	4	(	(	PUNCT
admet-34	49	5	volume	volume	NOUN
admet-34	49	6	vr	vr	PROPN
admet-34	49	7	)	)	PUNCT
admet-34	49	8	,	,	PUNCT
admet-34	49	9	due	due	ADP
admet-34	49	10	to	to	ADP
admet-34	49	11	peristalsis	peristalsis	NOUN
admet-34	49	12	,	,	PUNCT
admet-34	49	13	flows	flow	VERB
admet-34	49	14	from	from	ADP
admet-34	49	15	the	the	DET
admet-34	49	16	gastric	gastric	ADJ
admet-34	49	17	environment	environment	NOUN
admet-34	49	18	(	(	PUNCT
admet-34	49	19	gl	gl	NOUN
admet-34	49	20	)	)	PUNCT
admet-34	49	21	to	to	ADP
admet-34	49	22	the	the	DET
admet-34	49	23	small	small	ADJ
admet-34	49	24	(	(	PUNCT
admet-34	49	25	sil	sil	PROPN
admet-34	49	26	)	)	PUNCT
admet-34	49	27	and	and	CCONJ
admet-34	49	28	eventually	eventually	ADV
admet-34	49	29	the	the	DET
admet-34	49	30	large	large	ADJ
admet-34	49	31	(	(	PUNCT
admet-34	49	32	lil	lil	NOUN
admet-34	49	33	)	)	PUNCT
admet-34	49	34	intestine	intestine	NOUN
admet-34	49	35	.	.	PUNCT
admet-34	50	1	once	once	SCONJ
admet-34	50	2	it	it	PRON
admet-34	50	3	leaves	leave	VERB
admet-34	50	4	the	the	DET
admet-34	50	5	delivery	delivery	NOUN
admet-34	50	6	system	system	NOUN
admet-34	50	7	(	(	PUNCT
admet-34	50	8	a	a	DET
admet-34	50	9	non	non	ADJ
admet-34	50	10	-	-	ADJ
admet-34	50	11	eroding	eroding	ADJ
admet-34	50	12	poly	poly	ADJ
admet-34	50	13	-	-	PUNCT
admet-34	50	14	disperse	disperse	NOUN
admet-34	50	15	ensemble	ensemble	NOUN
admet-34	50	16	of	of	ADP
admet-34	50	17	polymeric	polymeric	ADJ
admet-34	50	18	particles	particle	NOUN
admet-34	50	19	)	)	PUNCT
admet-34	50	20	,	,	PUNCT
admet-34	50	21	the	the	DET
admet-34	50	22	drug	drug	NOUN
admet-34	50	23	reaches	reach	VERB
admet-34	50	24	the	the	DET
admet-34	50	25	release	release	NOUN
admet-34	50	26	environment	environment	NOUN
admet-34	50	27	fluids	fluid	NOUN
admet-34	50	28	and	and	CCONJ
admet-34	50	29	,	,	PUNCT
admet-34	50	30	then	then	ADV
admet-34	50	31	,	,	PUNCT
admet-34	50	32	it	it	PRON
admet-34	50	33	can	can	AUX
admet-34	50	34	permeate	permeate	VERB
admet-34	50	35	,	,	PUNCT
admet-34	50	36	by	by	ADP
admet-34	50	37	passive	passive	ADJ
admet-34	50	38	absorption	absorption	NOUN
admet-34	50	39	,	,	PUNCT
admet-34	50	40	the	the	DET
admet-34	50	41	gl	gl	PROPN
admet-34	50	42	,	,	PUNCT
admet-34	50	43	sil	sil	PROPN
admet-34	50	44	and	and	CCONJ
admet-34	50	45	lil	lil	VERB
admet-34	50	46	mucosa	mucosa	NOUN
admet-34	50	47	to	to	PART
admet-34	50	48	reach	reach	VERB
admet-34	50	49	the	the	DET
admet-34	50	50	gastrointestinal	gastrointestinal	ADJ
admet-34	50	51	circulatory	circulatory	ADJ
admet-34	50	52	system	system	NOUN
admet-34	50	53	(	(	PUNCT
admet-34	50	54	gics	gic	NOUN
admet-34	50	55	)	)	PUNCT
admet-34	50	56	.	.	PUNCT
admet-34	51	1	here	here	ADV
admet-34	51	2	it	it	PRON
admet-34	51	3	reaches	reach	VERB
admet-34	51	4	the	the	DET
admet-34	51	5	liver	liver	NOUN
admet-34	51	6	through	through	ADP
admet-34	51	7	the	the	DET
admet-34	51	8	portal	portal	ADJ
admet-34	51	9	vein	vein	NOUN
admet-34	51	10	(	(	PUNCT
admet-34	51	11	pv	pv	NOUN
admet-34	51	12	)	)	PUNCT
admet-34	51	13	.	.	PUNCT
admet-34	52	1	once	once	ADV
admet-34	52	2	in	in	ADP
admet-34	52	3	the	the	DET
admet-34	52	4	liver	liver	NOUN
admet-34	52	5	,	,	PUNCT
admet-34	52	6	it	it	PRON
admet-34	52	7	can	can	AUX
admet-34	52	8	be	be	AUX
admet-34	52	9	eliminated	eliminate	VERB
admet-34	52	10	by	by	ADP
admet-34	52	11	metabolic	metabolic	NOUN
admet-34	52	12	or	or	CCONJ
admet-34	52	13	biliary	biliary	NOUN
admet-34	52	14	clearance	clearance	NOUN
admet-34	52	15	(	(	PUNCT
admet-34	52	16	clh	clh	NOUN
admet-34	52	17	)	)	PUNCT
admet-34	52	18	or	or	CCONJ
admet-34	52	19	it	it	PRON
admet-34	52	20	may	may	AUX
admet-34	52	21	reach	reach	VERB
admet-34	52	22	the	the	DET
admet-34	52	23	plasma	plasma	NOUN
admet-34	52	24	through	through	ADP
admet-34	52	25	the	the	DET
admet-34	52	26	hepatic	hepatic	ADJ
admet-34	52	27	vein	vein	NOUN
admet-34	52	28	(	(	PUNCT
admet-34	52	29	hv	hv	PROPN
admet-34	52	30	)	)	PUNCT
admet-34	52	31	.	.	PUNCT
admet-34	53	1	once	once	ADV
admet-34	53	2	in	in	ADP
admet-34	53	3	the	the	DET
admet-34	53	4	plasma	plasma	NOUN
admet-34	53	5	,	,	PUNCT
admet-34	53	6	it	it	PRON
admet-34	53	7	may	may	AUX
admet-34	53	8	be	be	AUX
admet-34	53	9	exchanged	exchange	VERB
admet-34	53	10	with	with	ADP
admet-34	53	11	the	the	DET
admet-34	53	12	less	less	ADV
admet-34	53	13	perfused	perfused	ADJ
admet-34	53	14	tissues	tissue	NOUN
admet-34	53	15	,	,	PUNCT
admet-34	53	16	it	it	PRON
admet-34	53	17	may	may	AUX
admet-34	53	18	return	return	VERB
admet-34	53	19	to	to	ADP
admet-34	53	20	the	the	DET
admet-34	53	21	liver	liver	NOUN
admet-34	53	22	through	through	ADP
admet-34	53	23	the	the	DET
admet-34	53	24	hepatic	hepatic	ADJ
admet-34	53	25	artery	artery	NOUN
admet-34	53	26	(	(	PUNCT
admet-34	53	27	ha	ha	INTJ
admet-34	53	28	)	)	PUNCT
admet-34	53	29	or	or	CCONJ
admet-34	53	30	it	it	PRON
admet-34	53	31	can	can	AUX
admet-34	53	32	go	go	VERB
admet-34	53	33	to	to	ADP
admet-34	53	34	the	the	DET
admet-34	53	35	cigs	cig	NOUN
admet-34	53	36	following	follow	VERB
admet-34	53	37	the	the	DET
admet-34	53	38	portal	portal	ADJ
admet-34	53	39	vein	vein	NOUN
admet-34	53	40	(	(	PUNCT
admet-34	53	41	pv	pv	NOUN
admet-34	53	42	)	)	PUNCT
admet-34	53	43	.	.	PUNCT
admet-34	54	1	adapted	adapt	VERB
admet-34	54	2	from	from	ADP
admet-34	54	3	[	[	X
admet-34	54	4	10	10	NUM
admet-34	54	5	]	]	PUNCT
admet-34	54	6	.	.	PUNCT
admet-34	55	1	when	when	SCONJ
admet-34	55	2	ri	ri	PROPN
admet-34	55	3	is	be	AUX
admet-34	55	4	equal	equal	ADJ
admet-34	55	5	to	to	ADP
admet-34	55	6	zero	zero	NUM
admet-34	55	7	,	,	PUNCT
admet-34	55	8	the	the	DET
admet-34	55	9	release	release	NOUN
admet-34	55	10	environment	environment	NOUN
admet-34	55	11	is	be	AUX
admet-34	55	12	simply	simply	ADV
admet-34	55	13	a	a	DET
admet-34	55	14	cylinder	cylinder	NOUN
admet-34	55	15	of	of	ADP
admet-34	55	16	radius	radius	NOUN
admet-34	55	17	i	i	PRON
admet-34	55	18	glr	glr	PROPN
admet-34	55	19	,	,	PUNCT
admet-34	55	20	i	i	PRON
admet-34	55	21	silr	silr	PROPN
admet-34	56	1	or	or	CCONJ
admet-34	56	2	i	i	PRON
admet-34	56	3	lilr	lilr	VERB
admet-34	56	4	depending	depend	VERB
admet-34	56	5	on	on	ADP
admet-34	56	6	the	the	DET
admet-34	56	7	gi	gi	NOUN
admet-34	56	8	position	position	NOUN
admet-34	56	9	reached	reach	VERB
admet-34	56	10	by	by	ADP
admet-34	56	11	the	the	DET
admet-34	56	12	release	release	NOUN
admet-34	56	13	environment	environment	NOUN
admet-34	56	14	.	.	PUNCT
admet-34	57	1	when	when	SCONJ
admet-34	57	2	,	,	PUNCT
admet-34	57	3	on	on	ADP
admet-34	57	4	the	the	DET
admet-34	57	5	contrary	contrary	NOUN
admet-34	57	6	,	,	PUNCT
admet-34	57	7	ri	ri	PROPN
admet-34	57	8	is	be	AUX
admet-34	57	9	>	>	X
admet-34	57	10	0	0	NUM
admet-34	57	11	,	,	PUNCT
admet-34	57	12	the	the	DET
admet-34	57	13	release	release	NOUN
admet-34	57	14	environment	environment	NOUN
admet-34	57	15	assumes	assume	VERB
admet-34	57	16	the	the	DET
admet-34	57	17	shape	shape	NOUN
admet-34	57	18	of	of	ADP
admet-34	57	19	a	a	DET
admet-34	57	20	hollow	hollow	ADJ
admet-34	57	21	cylinder	cylinder	NOUN
admet-34	57	22	.	.	PUNCT
admet-34	58	1	in	in	ADP
admet-34	58	2	both	both	DET
admet-34	58	3	cases	case	NOUN
admet-34	58	4	,	,	PUNCT
admet-34	58	5	the	the	DET
admet-34	58	6	length	length	NOUN
admet-34	58	7	of	of	ADP
admet-34	58	8	the	the	DET
admet-34	58	9	release	release	NOUN
admet-34	58	10	environment	environment	NOUN
admet-34	58	11	is	be	AUX
admet-34	58	12	defined	define	VERB
admet-34	58	13	by	by	ADP
admet-34	58	14	(	(	PUNCT
admet-34	58	15	see	see	VERB
admet-34	58	16	figure	figure	NOUN
admet-34	58	17	1	1	NUM
admet-34	58	18	):	):	PUNCT
admet-34	58	19			NOUN
admet-34	58	20			SYM
admet-34	58	21			NOUN
admet-34	58	22			NOUN
admet-34	58	23	2	2	NUM
admet-34	58	24	2	2	NUM
admet-34	59	1	i	i	PRON
admet-34	59	2	i	i	PRON
admet-34	59	3	j	j	NOUN
admet-34	60	1	r	r	NOUN
admet-34	60	2	jπl	jπl	NOUN
admet-34	60	3	v	v	NOUN
admet-34	60	4	r	r	NOUN
admet-34	60	5	r	r	NOUN
admet-34	60	6			PROPN
admet-34	60	7			NOUN
admet-34	60	8			PROPN
admet-34	60	9			PROPN
admet-34	60	10			PROPN
admet-34	61	1			NOUN
admet-34	61	2			PROPN
admet-34	62	1			ADJ
admet-34	62	2			NOUN
admet-34	62	3			NOUN
admet-34	62	4	j	j	PROPN
admet-34	62	5	=	=	SYM
admet-34	62	6	gl	gl	PROPN
admet-34	62	7	,	,	PUNCT
admet-34	62	8	sil	sil	PROPN
admet-34	62	9	,	,	PUNCT
admet-34	62	10	lil	lil	X
admet-34	62	11	(	(	PUNCT
admet-34	62	12	1	1	X
admet-34	62	13	)	)	PUNCT
admet-34	62	14	admet	admet	PROPN
admet-34	62	15	&	&	CCONJ
admet-34	62	16	dmpk	dmpk	PROPN
admet-34	62	17	2(2	2(2	NUM
admet-34	62	18	)	)	PUNCT
admet-34	62	19	(	(	PUNCT
admet-34	62	20	2014	2014	NUM
admet-34	62	21	)	)	PUNCT
admet-34	62	22	80	80	NUM
admet-34	62	23	-	-	SYM
admet-34	62	24	97	97	NUM
admet-34	62	25	in	in	ADP
admet-34	62	26	vivo	vivo	ADJ
admet-34	62	27	drug	drug	NOUN
admet-34	62	28	release	release	NOUN
admet-34	62	29	and	and	CCONJ
admet-34	62	30	absorption	absorption	NOUN
admet-34	62	31	doi	doi	NOUN
admet-34	62	32	:	:	PUNCT
admet-34	62	33	10.5599	10.5599	NUM
admet-34	62	34	/	/	SYM
admet-34	62	35	admet.2.2.34	admet.2.2.34	NUM
admet-34	62	36	83	83	NUM
admet-34	62	37	it	it	PRON
admet-34	62	38	is	be	AUX
admet-34	62	39	,	,	PUNCT
admet-34	62	40	thus	thus	ADV
admet-34	62	41	,	,	PUNCT
admet-34	62	42	evident	evident	ADJ
admet-34	62	43	that	that	SCONJ
admet-34	62	44	the	the	DET
admet-34	62	45	choice	choice	NOUN
admet-34	62	46	of	of	ADP
admet-34	62	47	r	r	NOUN
admet-34	62	48	i	i	PRON
admet-34	62	49	serves	serve	VERB
admet-34	62	50	to	to	PART
admet-34	62	51	define	define	VERB
admet-34	62	52	the	the	DET
admet-34	62	53	(	(	PUNCT
admet-34	62	54	time	time	NOUN
admet-34	62	55	/	/	SYM
admet-34	62	56	position	position	NOUN
admet-34	62	57	dependent	dependent	ADJ
admet-34	62	58	)	)	PUNCT
admet-34	62	59	contact	contact	NOUN
admet-34	62	60	area	area	NOUN
admet-34	62	61	between	between	ADP
admet-34	62	62	the	the	DET
admet-34	62	63	release	release	NOUN
admet-34	62	64	environment	environment	NOUN
admet-34	62	65	and	and	CCONJ
admet-34	62	66	the	the	DET
admet-34	62	67	gi	gi	PROPN
admet-34	62	68	tract	tract	NOUN
admet-34	62	69	mucosa	mucosa	NOUN
admet-34	62	70	.	.	PUNCT
admet-34	63	1	consequently	consequently	ADV
admet-34	63	2	,	,	PUNCT
admet-34	63	3	r	r	NOUN
admet-34	63	4	i	i	PRON
admet-34	63	5	can	can	AUX
admet-34	63	6	be	be	AUX
admet-34	63	7	considered	consider	VERB
admet-34	63	8	a	a	DET
admet-34	63	9	model	model	NOUN
admet-34	63	10	fitting	fitting	ADJ
admet-34	63	11	parameter	parameter	NOUN
admet-34	63	12	.	.	PUNCT
admet-34	64	1	lacking	lack	VERB
admet-34	64	2	further	further	ADJ
admet-34	64	3	physiological	physiological	ADJ
admet-34	64	4	information	information	NOUN
admet-34	64	5	,	,	PUNCT
admet-34	64	6	in	in	ADP
admet-34	64	7	this	this	DET
admet-34	64	8	work	work	NOUN
admet-34	64	9	,	,	PUNCT
admet-34	64	10	the	the	DET
admet-34	64	11	most	most	ADV
admet-34	64	12	obvious	obvious	ADJ
admet-34	64	13	ri	ri	NOUN
admet-34	64	14	=	=	SYM
admet-34	64	15	0	0	NUM
admet-34	64	16	condition	condition	NOUN
admet-34	64	17	was	be	AUX
admet-34	64	18	considered	consider	VERB
admet-34	64	19	.	.	PUNCT
admet-34	65	1	due	due	ADP
admet-34	65	2	to	to	ADP
admet-34	65	3	the	the	DET
admet-34	65	4	well	well	ADV
admet-34	65	5	-	-	PUNCT
admet-34	65	6	known	know	VERB
admet-34	65	7	differences	difference	NOUN
admet-34	65	8	in	in	ADP
admet-34	65	9	the	the	DET
admet-34	65	10	morphology	morphology	NOUN
admet-34	65	11	/	/	SYM
admet-34	65	12	physiology	physiology	NOUN
admet-34	65	13	of	of	ADP
admet-34	65	14	each	each	DET
admet-34	65	15	zone	zone	NOUN
admet-34	65	16	,	,	PUNCT
admet-34	65	17	it	it	PRON
admet-34	65	18	is	be	AUX
admet-34	65	19	supposed	suppose	VERB
admet-34	65	20	that	that	SCONJ
admet-34	65	21	the	the	DET
admet-34	65	22	release	release	NOUN
admet-34	65	23	environment	environment	NOUN
admet-34	65	24	speed	speed	NOUN
admet-34	65	25	(	(	PUNCT
admet-34	65	26	vre	vre	NOUN
admet-34	65	27	)	)	PUNCT
admet-34	65	28	can	can	AUX
admet-34	65	29	vary	vary	VERB
admet-34	65	30	along	along	ADP
admet-34	65	31	the	the	DET
admet-34	65	32	gi	gi	NOUN
admet-34	65	33	tract	tract	NOUN
admet-34	65	34	and	and	CCONJ
admet-34	65	35	this	this	PRON
admet-34	65	36	is	be	AUX
admet-34	65	37	indirectly	indirectly	ADV
admet-34	65	38	considered	consider	VERB
admet-34	65	39	for	for	ADP
admet-34	65	40	by	by	ADP
admet-34	65	41	setting	set	VERB
admet-34	65	42	three	three	NUM
admet-34	65	43	different	different	ADJ
admet-34	65	44	residence	residence	NOUN
admet-34	65	45	(	(	PUNCT
admet-34	65	46	transit	transit	NOUN
admet-34	65	47	)	)	PUNCT
admet-34	65	48	times	time	NOUN
admet-34	65	49	(	(	PUNCT
admet-34	65	50	tgl	tgl	PROPN
admet-34	65	51	,	,	PUNCT
admet-34	65	52	tsil	tsil	NOUN
admet-34	65	53	and	and	CCONJ
admet-34	65	54	tlil	tlil	NOUN
admet-34	65	55	,	,	PUNCT
admet-34	65	56	respectively	respectively	ADV
admet-34	65	57	)	)	PUNCT
admet-34	65	58	,	,	PUNCT
admet-34	65	59	one	one	NUM
admet-34	65	60	for	for	ADP
admet-34	65	61	each	each	DET
admet-34	65	62	zone	zone	NOUN
admet-34	65	63	.	.	PUNCT
admet-34	66	1	release	release	VERB
admet-34	66	2	environment	environment	NOUN
admet-34	66	3	velocity	velocity	NOUN
admet-34	66	4	(	(	PUNCT
admet-34	66	5	vre	vre	NOUN
admet-34	66	6	)	)	PUNCT
admet-34	66	7	and	and	CCONJ
admet-34	66	8	position	position	NOUN
admet-34	66	9	in	in	ADP
admet-34	66	10	the	the	DET
admet-34	66	11	gi	gi	NOUN
admet-34	66	12	tract	tract	NOUN
admet-34	66	13	(	(	PUNCT
admet-34	66	14	pos	pos	NOUN
admet-34	66	15	)	)	PUNCT
admet-34	66	16	are	be	AUX
admet-34	66	17	connected	connect	VERB
admet-34	66	18	by	by	ADP
admet-34	66	19	the	the	DET
admet-34	66	20	following	follow	VERB
admet-34	66	21	relation	relation	NOUN
admet-34	66	22	:	:	PUNCT
admet-34	66	23	pos	pos	NOUN
admet-34	66	24	=	=	SYM
admet-34	66	25	∫0	∫0	ADP
admet-34	66	26	tvre*dt	tvre*dt	NOUN
admet-34	66	27	,	,	PUNCT
admet-34	66	28	where	where	SCONJ
admet-34	66	29	t	t	PROPN
admet-34	66	30	is	be	AUX
admet-34	66	31	time	time	NOUN
admet-34	66	32	.	.	PUNCT
admet-34	67	1	thus	thus	ADV
admet-34	67	2	,	,	PUNCT
admet-34	67	3	assuming	assume	VERB
admet-34	67	4	a	a	DET
admet-34	67	5	constant	constant	ADJ
admet-34	67	6	vre	vre	NOUN
admet-34	67	7	,	,	PUNCT
admet-34	67	8	the	the	DET
admet-34	67	9	transit	transit	NOUN
admet-34	67	10	time	time	NOUN
admet-34	67	11	(	(	PUNCT
admet-34	67	12	tt	tt	PROPN
admet-34	67	13	)	)	PUNCT
admet-34	67	14	of	of	ADP
admet-34	67	15	the	the	DET
admet-34	67	16	whole	whole	ADJ
admet-34	67	17	gi	gi	NOUN
admet-34	67	18	tract	tract	NOUN
admet-34	67	19	is	be	AUX
admet-34	67	20	given	give	VERB
admet-34	67	21	by	by	ADP
admet-34	67	22	tt	tt	PROPN
admet-34	67	23	=	=	PUNCT
admet-34	67	24	pos	pos	PROPN
admet-34	67	25	/	/	SYM
admet-34	67	26	vre	vre	NOUN
admet-34	67	27	where	where	SCONJ
admet-34	67	28	,	,	PUNCT
admet-34	67	29	now	now	ADV
admet-34	67	30	,	,	PUNCT
admet-34	67	31	pos	pos	PROPN
admet-34	67	32	indicates	indicate	VERB
admet-34	67	33	the	the	DET
admet-34	67	34	gi	gi	NOUN
admet-34	67	35	tract	tract	NOUN
admet-34	67	36	length	length	NOUN
admet-34	67	37	.	.	PUNCT
admet-34	68	1	alternatively	alternatively	ADV
admet-34	68	2	,	,	PUNCT
admet-34	68	3	always	always	ADV
admet-34	68	4	assuming	assume	VERB
admet-34	68	5	a	a	DET
admet-34	68	6	constant	constant	ADJ
admet-34	68	7	vre	vre	NOUN
admet-34	68	8	,	,	PUNCT
admet-34	68	9	after	after	ADP
admet-34	68	10	time	time	NOUN
admet-34	68	11	t	t	PROPN
admet-34	68	12	,	,	PUNCT
admet-34	68	13	the	the	DET
admet-34	68	14	position	position	NOUN
admet-34	68	15	gained	gain	VERB
admet-34	68	16	by	by	ADP
admet-34	68	17	the	the	DET
admet-34	68	18	release	release	NOUN
admet-34	68	19	environment	environment	NOUN
admet-34	68	20	is	be	AUX
admet-34	68	21	given	give	VERB
admet-34	68	22	by	by	ADP
admet-34	68	23	:	:	PUNCT
admet-34	68	24	pos	pos	NOUN
admet-34	68	25	=	=	SYM
admet-34	68	26	vre*t	vre*t	PROPN
admet-34	68	27	.	.	PUNCT
admet-34	69	1	once	once	ADV
admet-34	69	2	released	release	VERB
admet-34	69	3	,	,	PUNCT
admet-34	69	4	the	the	DET
admet-34	69	5	drug	drug	NOUN
admet-34	69	6	can	can	AUX
admet-34	69	7	undergo	undergo	VERB
admet-34	69	8	elimination	elimination	NOUN
admet-34	69	9	in	in	ADP
admet-34	69	10	the	the	DET
admet-34	69	11	release	release	NOUN
admet-34	69	12	environment	environment	NOUN
admet-34	69	13	(	(	PUNCT
admet-34	69	14	elimination	elimination	NOUN
admet-34	69	15	constant	constant	ADJ
admet-34	69	16	re	re	X
admet-34	69	17	elk	elk	PROPN
admet-34	69	18	,	,	PUNCT
admet-34	69	19	dimensionally	dimensionally	ADV
admet-34	69	20	time-1	time-1	NUM
admet-34	69	21	)	)	PUNCT
admet-34	69	22	and	and	CCONJ
admet-34	69	23	it	it	PRON
admet-34	69	24	can	can	AUX
admet-34	69	25	cross	cross	VERB
admet-34	69	26	,	,	PUNCT
admet-34	69	27	due	due	ADP
admet-34	69	28	to	to	ADP
admet-34	69	29	passive	passive	ADJ
admet-34	69	30	diffusion	diffusion	NOUN
admet-34	69	31	,	,	PUNCT
admet-34	69	32	the	the	DET
admet-34	69	33	gi	gi	NOUN
admet-34	69	34	mucosa	mucosa	NOUN
admet-34	69	35	according	accord	VERB
admet-34	69	36	to	to	ADP
admet-34	69	37	the	the	DET
admet-34	69	38	local	local	ADJ
admet-34	69	39	permeability	permeability	NOUN
admet-34	69	40	that	that	PRON
admet-34	69	41	depends	depend	VERB
admet-34	69	42	on	on	ADP
admet-34	69	43	the	the	DET
admet-34	69	44	vr	vr	NOUN
admet-34	69	45	position	position	NOUN
admet-34	69	46	in	in	ADP
admet-34	69	47	the	the	DET
admet-34	69	48	gi	gi	NOUN
admet-34	69	49	tract	tract	NOUN
admet-34	69	50	.	.	PUNCT
admet-34	70	1	then	then	ADV
admet-34	70	2	,	,	PUNCT
admet-34	70	3	the	the	DET
admet-34	70	4	drug	drug	NOUN
admet-34	70	5	reaches	reach	VERB
admet-34	70	6	the	the	DET
admet-34	70	7	gastrointestinal	gastrointestinal	ADJ
admet-34	70	8	circulatory	circulatory	ADJ
admet-34	70	9	system	system	NOUN
admet-34	70	10	(	(	PUNCT
admet-34	70	11	gics	gic	NOUN
admet-34	70	12	)	)	PUNCT
admet-34	70	13	,	,	PUNCT
admet-34	70	14	i.e.	i.e.	X
admet-34	70	15	the	the	DET
admet-34	70	16	ensemble	ensemble	NOUN
admet-34	70	17	of	of	ADP
admet-34	70	18	blood	blood	NOUN
admet-34	70	19	vessels	vessel	NOUN
admet-34	70	20	around	around	ADP
admet-34	70	21	the	the	DET
admet-34	70	22	gi	gi	NOUN
admet-34	70	23	tract	tract	NOUN
admet-34	70	24	.	.	PUNCT
admet-34	71	1	the	the	DET
admet-34	71	2	compartment	compartment	NOUN
admet-34	71	3	named	name	VERB
admet-34	71	4	gics	gic	NOUN
admet-34	71	5	(	(	PUNCT
admet-34	71	6	gastro	gastro	ADJ
admet-34	71	7	intestinal	intestinal	ADJ
admet-34	71	8	circulatory	circulatory	ADJ
admet-34	71	9	system	system	NOUN
admet-34	71	10	)	)	PUNCT
admet-34	71	11	is	be	AUX
admet-34	71	12	new	new	ADJ
admet-34	71	13	to	to	ADP
admet-34	71	14	pharmacokinetic	pharmacokinetic	ADJ
admet-34	71	15	modeling	modeling	NOUN
admet-34	71	16	,	,	PUNCT
admet-34	71	17	firstly	firstly	ADV
admet-34	71	18	introduced	introduce	VERB
admet-34	71	19	by	by	ADP
admet-34	71	20	[	[	X
admet-34	71	21	10	10	NUM
admet-34	71	22	]	]	PUNCT
admet-34	71	23	.	.	PUNCT
admet-34	72	1	basically	basically	ADV
admet-34	72	2	,	,	PUNCT
admet-34	72	3	it	it	PRON
admet-34	72	4	corresponds	correspond	VERB
admet-34	72	5	to	to	ADP
admet-34	72	6	the	the	DET
admet-34	72	7	ensemble	ensemble	NOUN
admet-34	72	8	of	of	ADP
admet-34	72	9	the	the	DET
admet-34	72	10	mesenteric	mesenteric	ADJ
admet-34	72	11	artery	artery	NOUN
admet-34	72	12	,	,	PUNCT
admet-34	72	13	the	the	DET
admet-34	72	14	portal	portal	NOUN
admet-34	72	15	vein	vein	VERB
admet-34	72	16	and	and	CCONJ
admet-34	72	17	the	the	DET
admet-34	72	18	ensemble	ensemble	ADJ
admet-34	72	19	of	of	ADP
admet-34	72	20	microcirculatory	microcirculatory	ADJ
admet-34	72	21	gastrointestinal	gastrointestinal	ADJ
admet-34	72	22	vessels	vessel	NOUN
admet-34	72	23	.	.	PUNCT
admet-34	73	1	this	this	DET
admet-34	73	2	section	section	NOUN
admet-34	73	3	of	of	ADP
admet-34	73	4	the	the	DET
admet-34	73	5	whole	whole	ADJ
admet-34	73	6	circulatory	circulatory	ADJ
admet-34	73	7	system	system	NOUN
admet-34	73	8	behaves	behave	VERB
admet-34	73	9	differently	differently	ADV
admet-34	73	10	from	from	ADP
admet-34	73	11	the	the	DET
admet-34	73	12	remaining	remaining	NOUN
admet-34	73	13	.	.	PUNCT
admet-34	74	1	in	in	ADP
admet-34	74	2	the	the	DET
admet-34	74	3	case	case	NOUN
admet-34	74	4	of	of	ADP
admet-34	74	5	parenteral	parenteral	ADJ
admet-34	74	6	administration	administration	NOUN
admet-34	74	7	,	,	PUNCT
admet-34	74	8	the	the	DET
admet-34	74	9	mesenteric	mesenteric	ADJ
admet-34	74	10	artery	artery	NOUN
admet-34	74	11	transports	transport	VERB
admet-34	74	12	the	the	DET
admet-34	74	13	drug	drug	NOUN
admet-34	74	14	towards	towards	ADP
admet-34	74	15	the	the	DET
admet-34	74	16	gastrointestinal	gastrointestinal	ADJ
admet-34	74	17	tract	tract	NOUN
admet-34	74	18	.	.	PUNCT
admet-34	75	1	in	in	ADP
admet-34	75	2	the	the	DET
admet-34	75	3	case	case	NOUN
admet-34	75	4	of	of	ADP
admet-34	75	5	enteral	enteral	ADJ
admet-34	75	6	administration	administration	NOUN
admet-34	75	7	,	,	PUNCT
admet-34	75	8	on	on	ADP
admet-34	75	9	the	the	DET
admet-34	75	10	contrary	contrary	NOUN
admet-34	75	11	,	,	PUNCT
admet-34	75	12	the	the	DET
admet-34	75	13	portal	portal	ADJ
admet-34	75	14	vein	vein	NOUN
admet-34	75	15	transports	transport	VERB
admet-34	75	16	the	the	DET
admet-34	75	17	drug	drug	NOUN
admet-34	75	18	from	from	ADP
admet-34	75	19	the	the	DET
admet-34	75	20	gastrointestinal	gastrointestinal	ADJ
admet-34	75	21	tract	tract	NOUN
admet-34	75	22	towards	towards	ADP
admet-34	75	23	the	the	DET
admet-34	75	24	liver	liver	NOUN
admet-34	75	25	(	(	PUNCT
admet-34	75	26	where	where	SCONJ
admet-34	75	27	the	the	DET
admet-34	75	28	drug	drug	NOUN
admet-34	75	29	experience	experience	NOUN
admet-34	75	30	the	the	DET
admet-34	75	31	socalled	socalled	ADJ
admet-34	75	32	first	first	ADJ
admet-34	75	33	-	-	PUNCT
admet-34	75	34	pass	pass	NOUN
admet-34	75	35	effect	effect	NOUN
admet-34	75	36	)	)	PUNCT
admet-34	75	37	to	to	PART
admet-34	75	38	finally	finally	ADV
admet-34	75	39	get	get	VERB
admet-34	75	40	the	the	DET
admet-34	75	41	remaining	remain	VERB
admet-34	75	42	part	part	NOUN
admet-34	75	43	of	of	ADP
admet-34	75	44	the	the	DET
admet-34	75	45	circulatory	circulatory	ADJ
admet-34	75	46	system	system	NOUN
admet-34	75	47	(	(	PUNCT
admet-34	75	48	here	here	ADV
admet-34	75	49	called	call	VERB
admet-34	75	50	“	"	PUNCT
admet-34	75	51	plasma	plasma	NOUN
admet-34	75	52	”	"	PUNCT
admet-34	75	53	)	)	PUNCT
admet-34	75	54	and	and	CCONJ
admet-34	75	55	the	the	DET
admet-34	75	56	other	other	ADJ
admet-34	75	57	tissues	tissue	NOUN
admet-34	75	58	.	.	PUNCT
admet-34	76	1	the	the	DET
admet-34	76	2	introduction	introduction	NOUN
admet-34	76	3	of	of	ADP
admet-34	76	4	the	the	DET
admet-34	76	5	gics	gic	NOUN
admet-34	76	6	has	have	AUX
admet-34	76	7	allowed	allow	VERB
admet-34	76	8	to	to	PART
admet-34	76	9	effectively	effectively	ADV
admet-34	76	10	transform	transform	VERB
admet-34	76	11	the	the	DET
admet-34	76	12	very	very	ADV
admet-34	76	13	detailed	detailed	ADJ
admet-34	76	14	pharmacokinetic	pharmacokinetic	ADJ
admet-34	76	15	model	model	NOUN
admet-34	76	16	proposed	propose	VERB
admet-34	76	17	by	by	ADP
admet-34	76	18	[	[	X
admet-34	76	19	14	14	NUM
admet-34	76	20	]	]	PUNCT
admet-34	76	21	,	,	PUNCT
admet-34	76	22	(	(	PUNCT
admet-34	76	23	consisting	consist	VERB
admet-34	76	24	in	in	ADP
admet-34	76	25	21	21	NUM
admet-34	76	26	compartments	compartment	NOUN
admet-34	76	27	and	and	CCONJ
admet-34	76	28	38	38	NUM
admet-34	76	29	ordinary	ordinary	ADJ
admet-34	76	30	differential	differential	ADJ
admet-34	76	31	equations	equation	NOUN
admet-34	76	32	with	with	ADP
admet-34	76	33	roughly	roughly	ADV
admet-34	76	34	one	one	NUM
admet-34	76	35	hundred	hundred	NUM
admet-34	76	36	parameters	parameter	NOUN
admet-34	76	37	)	)	PUNCT
admet-34	76	38	,	,	PUNCT
admet-34	76	39	into	into	ADP
admet-34	76	40	a	a	DET
admet-34	76	41	simple	simple	ADJ
admet-34	76	42	and	and	CCONJ
admet-34	76	43	effective	effective	ADJ
admet-34	76	44	model	model	NOUN
admet-34	76	45	(	(	PUNCT
admet-34	76	46	7	7	NUM
admet-34	76	47	compartments	compartment	NOUN
admet-34	76	48	and	and	CCONJ
admet-34	76	49	7	7	NUM
admet-34	76	50	ordinary	ordinary	ADJ
admet-34	76	51	differential	differential	ADJ
admet-34	76	52	equations	equation	NOUN
admet-34	76	53	,	,	PUNCT
admet-34	76	54	with	with	ADP
admet-34	76	55	about	about	ADV
admet-34	76	56	twenty	twenty	NUM
admet-34	76	57	parameters	parameter	NOUN
admet-34	76	58	)	)	PUNCT
admet-34	76	59	.	.	PUNCT
admet-34	77	1	this	this	DET
admet-34	77	2	effort	effort	NOUN
admet-34	77	3	saw	see	VERB
admet-34	77	4	several	several	ADJ
admet-34	77	5	researchers	researcher	NOUN
admet-34	77	6	spending	spend	VERB
admet-34	77	7	lot	lot	NOUN
admet-34	77	8	of	of	ADP
admet-34	77	9	work	work	NOUN
admet-34	77	10	,	,	PUNCT
admet-34	77	11	with	with	ADP
admet-34	77	12	limited	limited	ADJ
admet-34	77	13	and	and	CCONJ
admet-34	77	14	ineffective	ineffective	ADJ
admet-34	77	15	results	result	NOUN
admet-34	77	16	(	(	PUNCT
admet-34	77	17	see	see	VERB
admet-34	77	18	,	,	PUNCT
admet-34	77	19	for	for	ADP
admet-34	77	20	example	example	NOUN
admet-34	77	21	(	(	PUNCT
admet-34	77	22	see	see	VERB
admet-34	77	23	,	,	PUNCT
admet-34	77	24	for	for	ADP
admet-34	77	25	example	example	NOUN
admet-34	77	26	,	,	PUNCT
admet-34	77	27	[	[	X
admet-34	77	28	15	15	NUM
admet-34	77	29	]	]	NUM
admet-34	77	30	)	)	PUNCT
admet-34	77	31	.	.	PUNCT
admet-34	78	1	the	the	DET
admet-34	78	2	gics	gic	NOUN
admet-34	78	3	is	be	AUX
admet-34	78	4	assumed	assume	VERB
admet-34	78	5	to	to	PART
admet-34	78	6	be	be	AUX
admet-34	78	7	a	a	DET
admet-34	78	8	well	well	ADV
admet-34	78	9	-	-	PUNCT
admet-34	78	10	stirred	stir	VERB
admet-34	78	11	environment	environment	NOUN
admet-34	78	12	characterized	characterize	VERB
admet-34	78	13	by	by	ADP
admet-34	78	14	its	its	PRON
admet-34	78	15	own	own	ADJ
admet-34	78	16	constant	constant	ADJ
admet-34	78	17	volume	volume	NOUN
admet-34	78	18	(	(	PUNCT
admet-34	78	19	vgics	vgic	NOUN
admet-34	78	20	)	)	PUNCT
admet-34	78	21	and	and	CCONJ
admet-34	78	22	time	time	NOUN
admet-34	78	23	dependent	dependent	ADJ
admet-34	78	24	drug	drug	NOUN
admet-34	78	25	concentration	concentration	NOUN
admet-34	78	26	(	(	PUNCT
admet-34	78	27	cgics	cgic	NOUN
admet-34	78	28	)	)	PUNCT
admet-34	78	29	.	.	PUNCT
admet-34	79	1	the	the	DET
admet-34	79	2	portal	portal	PROPN
admet-34	79	3	vein	vein	NOUN
admet-34	79	4	ensures	ensure	VERB
admet-34	79	5	the	the	DET
admet-34	79	6	convective	convective	ADJ
admet-34	79	7	drug	drug	NOUN
admet-34	79	8	transport	transport	NOUN
admet-34	79	9	(	(	PUNCT
admet-34	79	10	blood	blood	NOUN
admet-34	79	11	volumetric	volumetric	NOUN
admet-34	79	12	flow	flow	NOUN
admet-34	79	13	qpv	qpv	PROPN
admet-34	79	14	)	)	PUNCT
admet-34	79	15	from	from	ADP
admet-34	79	16	the	the	DET
admet-34	79	17	gics	gic	NOUN
admet-34	79	18	to	to	ADP
admet-34	79	19	the	the	DET
admet-34	79	20	liver	liver	NOUN
admet-34	79	21	(	(	PUNCT
admet-34	79	22	volume	volume	NOUN
admet-34	79	23	vl	vl	PROPN
admet-34	79	24	)	)	PUNCT
admet-34	79	25	.	.	PUNCT
admet-34	80	1	in	in	ADP
admet-34	80	2	this	this	DET
admet-34	80	3	well	well	ADV
admet-34	80	4	-	-	PUNCT
admet-34	80	5	stirred	stir	VERB
admet-34	80	6	environment	environment	NOUN
admet-34	80	7	,	,	PUNCT
admet-34	80	8	drug	drug	NOUN
admet-34	80	9	concentration	concentration	NOUN
admet-34	80	10	(	(	PUNCT
admet-34	80	11	cl	cl	NOUN
admet-34	80	12	)	)	PUNCT
admet-34	80	13	varies	vary	VERB
admet-34	80	14	due	due	ADJ
admet-34	80	15	to	to	ADP
admet-34	80	16	hepatic	hepatic	ADJ
admet-34	80	17	clearance	clearance	NOUN
admet-34	80	18	(	(	PUNCT
admet-34	80	19	clh	clh	NOUN
admet-34	80	20	;	;	PUNCT
admet-34	80	21	dimensionally	dimensionally	ADV
admet-34	80	22	a	a	DET
admet-34	80	23	volumetric	volumetric	ADJ
admet-34	80	24	flow	flow	NOUN
admet-34	80	25	)	)	PUNCT
admet-34	80	26	and	and	CCONJ
admet-34	80	27	convective	convective	ADJ
admet-34	80	28	transport	transport	NOUN
admet-34	80	29	by	by	ADP
admet-34	80	30	the	the	DET
admet-34	80	31	hepatic	hepatic	ADJ
admet-34	80	32	vein	vein	NOUN
admet-34	80	33	and	and	CCONJ
admet-34	80	34	the	the	DET
admet-34	80	35	hepatic	hepatic	ADJ
admet-34	80	36	artery	artery	NOUN
admet-34	80	37	.	.	PUNCT
admet-34	81	1	the	the	DET
admet-34	81	2	hepatic	hepatic	ADJ
admet-34	81	3	vein	vein	NOUN
admet-34	81	4	connects	connect	VERB
admet-34	81	5	the	the	DET
admet-34	81	6	liver	liver	NOUN
admet-34	81	7	to	to	ADP
admet-34	81	8	the	the	DET
admet-34	81	9	highly	highly	ADV
admet-34	81	10	perfused	perfused	ADJ
admet-34	81	11	tissues	tissue	NOUN
admet-34	81	12	and	and	CCONJ
admet-34	81	13	organs	organ	NOUN
admet-34	81	14	(	(	PUNCT
admet-34	81	15	where	where	SCONJ
admet-34	81	16	drug	drug	NOUN
admet-34	81	17	concentration	concentration	NOUN
admet-34	81	18	is	be	AUX
admet-34	81	19	assumed	assume	VERB
admet-34	81	20	equal	equal	ADJ
admet-34	81	21	to	to	ADP
admet-34	81	22	plasma	plasma	NOUN
admet-34	81	23	’s	’s	PART
admet-34	81	24	)	)	PUNCT
admet-34	81	25	by	by	ADP
admet-34	81	26	a	a	DET
admet-34	81	27	volumetric	volumetric	NOUN
admet-34	81	28	blood	blood	NOUN
admet-34	81	29	flow	flow	NOUN
admet-34	81	30	qhv	qhv	NOUN
admet-34	81	31	,	,	PUNCT
admet-34	81	32	while	while	SCONJ
admet-34	81	33	the	the	DET
admet-34	81	34	hepatic	hepatic	ADJ
admet-34	81	35	artery	artery	NOUN
admet-34	81	36	brings	bring	VERB
admet-34	81	37	back	back	ADP
admet-34	81	38	the	the	DET
admet-34	81	39	drug	drug	NOUN
admet-34	81	40	from	from	ADP
admet-34	81	41	the	the	DET
admet-34	81	42	plasma	plasma	NOUN
admet-34	81	43	environment	environment	NOUN
admet-34	81	44	to	to	ADP
admet-34	81	45	the	the	DET
admet-34	81	46	liver	liver	NOUN
admet-34	81	47	(	(	PUNCT
admet-34	81	48	volumetric	volumetric	ADJ
admet-34	81	49	blood	blood	NOUN
admet-34	81	50	flow	flow	NOUN
admet-34	81	51	qha	qha	NOUN
admet-34	81	52	)	)	PUNCT
admet-34	81	53	.	.	PUNCT
admet-34	82	1	once	once	ADV
admet-34	82	2	in	in	ADP
admet-34	82	3	the	the	DET
admet-34	82	4	plasma	plasma	NOUN
admet-34	82	5	,	,	PUNCT
admet-34	82	6	the	the	DET
admet-34	82	7	drug	drug	NOUN
admet-34	82	8	can	can	AUX
admet-34	82	9	undergo	undergo	VERB
admet-34	82	10	elimination	elimination	NOUN
admet-34	82	11	(	(	PUNCT
admet-34	82	12	*	*	PUNCT
admet-34	82	13	elk	elk	PROPN
admet-34	82	14	is	be	AUX
admet-34	82	15	the	the	DET
admet-34	82	16	elimination	elimination	NOUN
admet-34	82	17	constant	constant	ADJ
admet-34	82	18	,	,	PUNCT
admet-34	82	19	dimensionally	dimensionally	ADV
admet-34	82	20	a	a	DET
admet-34	82	21	volumetric	volumetric	NOUN
admet-34	82	22	flow	flow	NOUN
admet-34	82	23	)	)	PUNCT
admet-34	82	24	,	,	PUNCT
admet-34	82	25	convective	convective	ADJ
admet-34	82	26	transport	transport	NOUN
admet-34	82	27	back	back	ADV
admet-34	82	28	to	to	ADP
admet-34	82	29	the	the	DET
admet-34	82	30	gics	gic	NOUN
admet-34	82	31	according	accord	VERB
admet-34	82	32	to	to	ADP
admet-34	82	33	the	the	DET
admet-34	82	34	portal	portal	ADJ
admet-34	82	35	vein	vein	NOUN
admet-34	82	36	(	(	PUNCT
admet-34	82	37	again	again	ADV
admet-34	82	38	,	,	PUNCT
admet-34	82	39	blood	blood	NOUN
admet-34	82	40	volumetric	volumetric	NOUN
admet-34	82	41	flow	flow	NOUN
admet-34	82	42	qpv	qpv	PROPN
admet-34	82	43	)	)	PUNCT
admet-34	82	44	and	and	CCONJ
admet-34	82	45	exchange	exchange	NOUN
admet-34	82	46	with	with	ADP
admet-34	82	47	the	the	DET
admet-34	82	48	poorly	poorly	ADV
admet-34	82	49	perfused	perfuse	VERB
admet-34	82	50	tissues	tissue	NOUN
admet-34	82	51	and	and	CCONJ
admet-34	82	52	organs	organ	NOUN
admet-34	82	53	,	,	PUNCT
admet-34	82	54	indicated	indicate	VERB
admet-34	82	55	as	as	ADP
admet-34	82	56	“	"	PUNCT
admet-34	82	57	tissues	tissue	NOUN
admet-34	82	58	”	"	PUNCT
admet-34	82	59	in	in	ADP
admet-34	82	60	figure	figure	NOUN
admet-34	82	61	1	1	NUM
admet-34	82	62	.	.	PUNCT
admet-34	82	63	drug	drug	NOUN
admet-34	82	64	exchange	exchange	NOUN
admet-34	82	65	between	between	ADP
admet-34	82	66	plasma	plasma	NOUN
admet-34	82	67	and	and	CCONJ
admet-34	82	68	tissues	tissue	NOUN
admet-34	82	69	is	be	AUX
admet-34	82	70	ruled	rule	VERB
admet-34	82	71	by	by	ADP
admet-34	82	72	the	the	DET
admet-34	82	73	forward	forward	ADJ
admet-34	82	74	mass	mass	NOUN
admet-34	82	75	transfer	transfer	NOUN
admet-34	82	76	coefficient	coefficient	NOUN
admet-34	82	77	*	*	PUNCT
admet-34	82	78	ptk	ptk	NOUN
admet-34	82	79	(	(	PUNCT
admet-34	82	80	from	from	ADP
admet-34	82	81	the	the	DET
admet-34	82	82	plasma	plasma	NOUN
admet-34	82	83	to	to	ADP
admet-34	82	84	the	the	DET
admet-34	82	85	tissues	tissue	NOUN
admet-34	82	86	;	;	PUNCT
admet-34	82	87	dimensionally	dimensionally	ADV
admet-34	82	88	a	a	DET
admet-34	82	89	volumetric	volumetric	ADJ
admet-34	82	90	flow	flow	NOUN
admet-34	82	91	)	)	PUNCT
admet-34	82	92	and	and	CCONJ
admet-34	82	93	the	the	DET
admet-34	82	94	reverse	reverse	ADJ
admet-34	82	95	term	term	NOUN
admet-34	82	96	*	*	PUNCT
admet-34	82	97	tpk	tpk	NOUN
admet-34	82	98	(	(	PUNCT
admet-34	82	99	from	from	ADP
admet-34	82	100	tissues	tissue	NOUN
admet-34	82	101	to	to	ADP
admet-34	82	102	plasma	plasma	NOUN
admet-34	82	103	;	;	PUNCT
admet-34	82	104	dimensionally	dimensionally	ADV
admet-34	82	105	a	a	DET
admet-34	82	106	volumetric	volumetric	ADJ
admet-34	82	107	flow	flow	NOUN
admet-34	82	108	)	)	PUNCT
admet-34	82	109	.	.	PUNCT
admet-34	83	1	although	although	SCONJ
admet-34	83	2	*	*	PUNCT
admet-34	83	3	elk	elk	PROPN
admet-34	83	4	,	,	PUNCT
admet-34	83	5	*	*	PUNCT
admet-34	83	6	tpk	tpk	NOUN
admet-34	83	7	and	and	CCONJ
admet-34	83	8	*	*	PUNCT
admet-34	83	9	ptk	ptk	NOUN
admet-34	83	10	constants	constant	NOUN
admet-34	83	11	are	be	AUX
admet-34	83	12	not	not	PART
admet-34	83	13	commonly	commonly	ADV
admet-34	83	14	used	use	VERB
admet-34	83	15	in	in	ADP
admet-34	83	16	the	the	DET
admet-34	83	17	pk	pk	NOUN
admet-34	83	18	field	field	NOUN
admet-34	83	19	,	,	PUNCT
admet-34	83	20	their	their	PRON
admet-34	83	21	use	use	NOUN
admet-34	83	22	is	be	AUX
admet-34	83	23	del	del	PROPN
admet-34	83	24	cont	cont	PROPN
admet-34	83	25	et	et	PROPN
admet-34	83	26	al	al	PROPN
admet-34	83	27	.	.	PROPN
admet-34	83	28	admet	admet	PROPN
admet-34	83	29	&	&	CCONJ
admet-34	83	30	dmpk	dmpk	PROPN
admet-34	83	31	2(2	2(2	NUM
admet-34	83	32	)	)	PUNCT
admet-34	83	33	(	(	PUNCT
admet-34	83	34	2014	2014	NUM
admet-34	83	35	)	)	PUNCT
admet-34	83	36	80	80	NUM
admet-34	83	37	-	-	SYM
admet-34	83	38	97	97	NUM
admet-34	83	39	84	84	NUM
admet-34	83	40	mandatory	mandatory	ADJ
admet-34	83	41	in	in	ADP
admet-34	83	42	this	this	DET
admet-34	83	43	case	case	NOUN
admet-34	83	44	.	.	PUNCT
admet-34	84	1	indeed	indeed	ADV
admet-34	84	2	,	,	PUNCT
admet-34	84	3	in	in	ADP
admet-34	84	4	order	order	NOUN
admet-34	84	5	ensure	ensure	VERB
admet-34	84	6	that	that	SCONJ
admet-34	84	7	all	all	DET
admet-34	84	8	the	the	DET
admet-34	84	9	kinetic	kinetic	ADJ
admet-34	84	10	equations	equation	NOUN
admet-34	84	11	ruling	rule	VERB
admet-34	84	12	drug	drug	NOUN
admet-34	84	13	concentration	concentration	NOUN
admet-34	84	14	in	in	ADP
admet-34	84	15	the	the	DET
admet-34	84	16	different	different	ADJ
admet-34	84	17	environments	environment	NOUN
admet-34	84	18	(	(	PUNCT
admet-34	84	19	gics	gic	NOUN
admet-34	84	20	,	,	PUNCT
admet-34	84	21	liver	liver	NOUN
admet-34	84	22	,	,	PUNCT
admet-34	84	23	plasma	plasma	NOUN
admet-34	84	24	and	and	CCONJ
admet-34	84	25	tissues	tissue	NOUN
admet-34	84	26	)	)	PUNCT
admet-34	84	27	represent	represent	VERB
admet-34	84	28	true	true	ADJ
admet-34	84	29	mass	mass	NOUN
admet-34	84	30	balances	balance	NOUN
admet-34	84	31	referring	refer	VERB
admet-34	84	32	to	to	ADP
admet-34	84	33	the	the	DET
admet-34	84	34	drug	drug	NOUN
admet-34	84	35	,	,	PUNCT
admet-34	84	36	*	*	PUNCT
admet-34	84	37	elk	elk	NOUN
admet-34	84	38	,	,	PUNCT
admet-34	84	39	*	*	PUNCT
admet-34	84	40	tpk	tpk	NOUN
admet-34	84	41	and	and	CCONJ
admet-34	84	42	*	*	PUNCT
admet-34	84	43	ptk	ptk	NOUN
admet-34	84	44	must	must	AUX
admet-34	84	45	be	be	AUX
admet-34	84	46	volumetric	volumetric	ADJ
admet-34	84	47	flows	flow	NOUN
admet-34	84	48	[	[	X
admet-34	84	49	12	12	NUM
admet-34	84	50	]	]	PUNCT
admet-34	84	51	.	.	PUNCT
admet-34	85	1	however	however	ADV
admet-34	85	2	,	,	PUNCT
admet-34	85	3	as	as	SCONJ
admet-34	85	4	this	this	PRON
admet-34	85	5	is	be	AUX
admet-34	85	6	not	not	PART
admet-34	85	7	a	a	DET
admet-34	85	8	common	common	ADJ
admet-34	85	9	choice	choice	NOUN
admet-34	85	10	and	and	CCONJ
admet-34	85	11	it	it	PRON
admet-34	85	12	can	can	AUX
admet-34	85	13	generate	generate	VERB
admet-34	85	14	confusion	confusion	NOUN
admet-34	85	15	in	in	ADP
admet-34	85	16	the	the	DET
admet-34	85	17	reader	reader	NOUN
admet-34	85	18	,	,	PUNCT
admet-34	85	19	model	model	NOUN
admet-34	85	20	equations	equation	NOUN
admet-34	85	21	have	have	AUX
admet-34	85	22	been	be	AUX
admet-34	85	23	re	re	VERB
admet-34	85	24	-	-	VERB
admet-34	85	25	arranged	arrange	VERB
admet-34	85	26	so	so	SCONJ
admet-34	85	27	that	that	SCONJ
admet-34	85	28	more	more	ADV
admet-34	85	29	common	common	ADJ
admet-34	85	30	drug	drug	NOUN
admet-34	85	31	elimination	elimination	NOUN
admet-34	85	32	(	(	PUNCT
admet-34	85	33	kel	kel	NOUN
admet-34	85	34	,	,	PUNCT
admet-34	85	35	time	time	NOUN
admet-34	85	36	-1	-1	PUNCT
admet-34	85	37	)	)	PUNCT
admet-34	85	38	and	and	CCONJ
admet-34	85	39	plasma	plasma	NOUN
admet-34	85	40	–	–	PUNCT
admet-34	85	41	tissues	tissue	NOUN
admet-34	85	42	exchange	exchange	NOUN
admet-34	85	43	constants	constant	NOUN
admet-34	85	44	(	(	PUNCT
admet-34	85	45	kpt	kpt	PROPN
admet-34	85	46	,	,	PUNCT
admet-34	85	47	time	time	NOUN
admet-34	85	48	-1	-1	NOUN
admet-34	85	49	;	;	PUNCT
admet-34	85	50	ktp	ktp	PROPN
admet-34	85	51	,	,	PUNCT
admet-34	85	52	time	time	NOUN
admet-34	85	53	-1	-1	PUNCT
admet-34	85	54	)	)	PUNCT
admet-34	85	55	appear	appear	VERB
admet-34	85	56	in	in	ADP
admet-34	85	57	place	place	NOUN
admet-34	85	58	of	of	ADP
admet-34	85	59	*	*	PROPN
admet-34	85	60	elk	elk	NOUN
admet-34	85	61	,	,	PUNCT
admet-34	85	62	*	*	PUNCT
admet-34	85	63	tpk	tpk	NOUN
admet-34	85	64	and	and	CCONJ
admet-34	85	65	*	*	PUNCT
admet-34	85	66	ptk	ptk	NOUN
admet-34	85	67	.	.	PUNCT
admet-34	86	1	the	the	DET
admet-34	86	2	reminiscence	reminiscence	NOUN
admet-34	86	3	of	of	ADP
admet-34	86	4	*	*	PROPN
admet-34	86	5	elk	elk	PROPN
admet-34	86	6	,	,	PUNCT
admet-34	86	7	*	*	PUNCT
admet-34	86	8	tpk	tpk	NOUN
admet-34	86	9	and	and	CCONJ
admet-34	86	10	*	*	PUNCT
admet-34	86	11	ptk	ptk	PROPN
admet-34	86	12	in	in	ADP
admet-34	86	13	eqs	eqs	PROPN
admet-34	86	14	.	.	PUNCT
admet-34	87	1	(	(	PUNCT
admet-34	87	2	3	3	NUM
admet-34	87	3	)	)	PUNCT
admet-34	87	4	–	–	PUNCT
admet-34	87	5	(	(	PUNCT
admet-34	87	6	5	5	NUM
admet-34	87	7	)	)	PUNCT
admet-34	87	8	is	be	AUX
admet-34	87	9	represented	represent	VERB
admet-34	87	10	by	by	ADP
admet-34	87	11	parameter	parameter	PROPN
admet-34	87	12	f	f	PROPN
admet-34	87	13	(	(	PUNCT
admet-34	87	14	see	see	VERB
admet-34	87	15	eq	eq	ADP
admet-34	87	16	.	.	PUNCT
admet-34	88	1	(	(	PUNCT
admet-34	88	2	8)	8)	NUM
admet-34	88	3	)	)	PUNCT
admet-34	88	4	that	that	PRON
admet-34	88	5	expresses	express	VERB
admet-34	88	6	the	the	DET
admet-34	88	7	ratio	ratio	NOUN
admet-34	88	8	between	between	ADP
admet-34	88	9	the	the	DET
admet-34	88	10	plasma	plasma	NOUN
admet-34	88	11	(	(	PUNCT
admet-34	88	12	vp	vp	NOUN
admet-34	88	13	)	)	PUNCT
admet-34	88	14	and	and	CCONJ
admet-34	88	15	the	the	DET
admet-34	88	16	tissues	tissue	NOUN
admet-34	88	17	(	(	PUNCT
admet-34	88	18	vt	vt	NOUN
admet-34	88	19	)	)	PUNCT
admet-34	88	20	volumes	volume	NOUN
admet-34	88	21	.	.	PUNCT
admet-34	89	1	accordingly	accordingly	ADV
admet-34	89	2	,	,	PUNCT
admet-34	89	3	the	the	DET
admet-34	89	4	pbpk	pbpk	PROPN
admet-34	89	5	model	model	NOUN
admet-34	89	6	discussed	discuss	VERB
admet-34	89	7	and	and	CCONJ
admet-34	89	8	reported	report	VERB
admet-34	89	9	in	in	ADP
admet-34	89	10	figure	figure	NOUN
admet-34	89	11	1	1	NUM
admet-34	89	12	,	,	PUNCT
admet-34	89	13	is	be	AUX
admet-34	89	14	mathematically	mathematically	ADV
admet-34	89	15	represented	represent	VERB
admet-34	89	16	by	by	ADP
admet-34	89	17	the	the	DET
admet-34	89	18	following	follow	VERB
admet-34	89	19	system	system	NOUN
admet-34	89	20	of	of	ADP
admet-34	89	21	ordinary	ordinary	ADJ
admet-34	89	22	differential	differential	ADJ
admet-34	89	23	equations	equation	NOUN
admet-34	89	24	where	where	SCONJ
admet-34	89	25	t	t	PROPN
admet-34	89	26	is	be	AUX
admet-34	89	27	the	the	DET
admet-34	89	28	independent	independent	ADJ
admet-34	89	29	variable	variable	NOUN
admet-34	89	30	,	,	PUNCT
admet-34	89	31	time	time	NOUN
admet-34	89	32	:	:	PUNCT
admet-34	89	33			NOUN
admet-34	89	34			SYM
admet-34	89	35			NOUN
admet-34	89	36			PUNCT
admet-34	89	37	j	j	PROPN
admet-34	89	38	jgics	jgic	VERB
admet-34	89	39	pv	pv	INTJ
admet-34	89	40	r	r	NOUN
admet-34	89	41	gics	gic	NOUN
admet-34	89	42	p	p	PROPN
admet-34	89	43	gics	gic	NOUN
admet-34	89	44	gics	gic	NOUN
admet-34	89	45	gics	gic	NOUN
admet-34	90	1	d	d	PROPN
admet-34	90	2	d	d	X
admet-34	90	3	apc	apc	PROPN
admet-34	90	4	q	q	PROPN
admet-34	90	5	c	c	NOUN
admet-34	90	6	c	c	NOUN
admet-34	90	7	c	c	NOUN
admet-34	90	8	c	c	PROPN
admet-34	90	9	t	t	PROPN
admet-34	90	10	v	v	NOUN
admet-34	90	11	v	v	ADP
admet-34	90	12			PROPN
admet-34	90	13			PROPN
admet-34	90	14			PUNCT
admet-34	90	15			NOUN
admet-34	90	16	gics	gic	NOUN
admet-34	90	17	(	(	PUNCT
admet-34	90	18	2	2	NUM
admet-34	90	19	)	)	PUNCT
admet-34	90	20	l	l	NOUN
admet-34	90	21	pv	pv	INTJ
admet-34	91	1	ha	ha	INTJ
admet-34	91	2	hv	hv	PROPN
admet-34	91	3	lh	lh	PROPN
admet-34	91	4	gics	gic	NOUN
admet-34	91	5	p	p	PROPN
admet-34	92	1	l	l	PROPN
admet-34	92	2	l	l	NOUN
admet-34	92	3	l	l	NOUN
admet-34	92	4	l	l	PUNCT
admet-34	93	1	d	d	PUNCT
admet-34	93	2	d	d	X
admet-34	93	3	c	c	NOUN
admet-34	93	4	q	q	X
admet-34	93	5	q	q	X
admet-34	93	6	q	q	X
admet-34	93	7	c	c	NOUN
admet-34	93	8	c	c	NOUN
admet-34	94	1	c	c	NOUN
admet-34	94	2	c	c	PROPN
admet-34	94	3	t	t	PROPN
admet-34	94	4	v	v	NOUN
admet-34	94	5	v	v	NOUN
admet-34	94	6	v	v	ADP
admet-34	94	7			PROPN
admet-34	94	8			PROPN
admet-34	94	9			ADJ
admet-34	94	10			PROPN
admet-34	94	11			NOUN
admet-34	94	12			PROPN
admet-34	94	13			PROPN
admet-34	94	14			PROPN
admet-34	95	1			PROPN
admet-34	95	2			PROPN
admet-34	95	3	liver	liver	NOUN
admet-34	95	4	(	(	PUNCT
admet-34	95	5	3	3	NUM
admet-34	95	6	)	)	PUNCT
admet-34	95	7			NOUN
admet-34	95	8	p	p	VERB
admet-34	95	9	hv	hv	NOUN
admet-34	95	10	pv	pv	INTJ
admet-34	96	1	ha	ha	INTJ
admet-34	96	2	l	l	PROPN
admet-34	96	3	p	p	PROPN
admet-34	96	4	el	el	PROPN
admet-34	96	5	pt	pt	PROPN
admet-34	96	6	p	p	X
admet-34	96	7	tp	tp	ADP
admet-34	96	8	t	t	PROPN
admet-34	97	1	p	p	X
admet-34	97	2	p	p	PROPN
admet-34	97	3	d	d	X
admet-34	97	4	d	d	X
admet-34	97	5	c	c	NOUN
admet-34	97	6	q	q	NOUN
admet-34	97	7	q	q	X
admet-34	97	8	q	q	X
admet-34	98	1	c	c	NOUN
admet-34	98	2	c	c	NOUN
admet-34	99	1	k	k	PROPN
admet-34	99	2	k	k	PROPN
admet-34	99	3	c	c	PROPN
admet-34	100	1	k	k	PROPN
admet-34	100	2	c	c	PROPN
admet-34	100	3	t	t	PROPN
admet-34	100	4	v	v	NOUN
admet-34	100	5	v	v	ADP
admet-34	100	6			ADJ
admet-34	100	7			PROPN
admet-34	100	8			PROPN
admet-34	100	9			PROPN
admet-34	100	10			PUNCT
admet-34	100	11			PUNCT
admet-34	101	1			NOUN
admet-34	101	2			PROPN
admet-34	101	3			PROPN
admet-34	101	4			PROPN
admet-34	102	1			PROPN
admet-34	102	2			PROPN
admet-34	102	3	plasma	plasma	NOUN
admet-34	102	4	(	(	PUNCT
admet-34	102	5	4	4	NUM
admet-34	102	6	)	)	PUNCT
admet-34	102	7	t	t	NOUN
admet-34	102	8	pt	pt	INTJ
admet-34	102	9	p	p	X
admet-34	102	10	tp	tp	ADP
admet-34	102	11	t	t	PROPN
admet-34	103	1	d	d	X
admet-34	103	2	d	d	PROPN
admet-34	103	3	c	c	X
admet-34	103	4	k	k	PROPN
admet-34	103	5	fc	fc	PROPN
admet-34	103	6	k	k	PROPN
admet-34	103	7	fc	fc	PROPN
admet-34	103	8	t	t	PROPN
admet-34	103	9			PROPN
admet-34	103	10			PROPN
admet-34	103	11	tissues	tissue	NOUN
admet-34	103	12	(	(	PUNCT
admet-34	103	13	5	5	NUM
admet-34	103	14	)	)	PUNCT
admet-34	103	15	reel	reel	NOUN
admet-34	103	16	r	r	NOUN
admet-34	103	17	el	el	PROPN
admet-34	103	18	r	r	NOUN
admet-34	103	19	lh	lh	PROPN
admet-34	103	20	l	l	PROPN
admet-34	103	21	el	el	PROPN
admet-34	104	1	p	p	PROPN
admet-34	104	2	p	p	PROPN
admet-34	105	1	d	d	X
admet-34	105	2	d	d	PROPN
admet-34	105	3	m	m	NOUN
admet-34	105	4	v	v	ADJ
admet-34	105	5	k	k	PROPN
admet-34	105	6	c	c	NOUN
admet-34	105	7	c	c	NOUN
admet-34	105	8	c	c	PROPN
admet-34	105	9	k	k	PROPN
admet-34	105	10	v	v	INTJ
admet-34	105	11	c	c	PROPN
admet-34	105	12	t	t	PROPN
admet-34	105	13			PROPN
admet-34	105	14			ADV
admet-34	105	15			X
admet-34	105	16	(	(	PUNCT
admet-34	105	17	6	6	NUM
admet-34	105	18	)	)	PUNCT
admet-34	106	1	where	where	SCONJ
admet-34	106	2	:	:	PUNCT
admet-34	106	3	j	j	PROPN
admet-34	106	4	j	j	PROPN
admet-34	106	5	j2πra	j2πra	PROPN
admet-34	106	6	l	l	PROPN
admet-34	106	7	j	j	PROPN
admet-34	106	8	=	=	SYM
admet-34	106	9	gl	gl	PROPN
admet-34	106	10	,	,	PUNCT
admet-34	106	11	sil	sil	PROPN
admet-34	106	12	,	,	PUNCT
admet-34	106	13	lil	lil	PROPN
admet-34	106	14	j	j	PROPN
admet-34	106	15	,	,	PUNCT
admet-34	106	16	,	,	PUNCT
admet-34	106	17	gl	gl	PROPN
admet-34	106	18	sil	sil	PROPN
admet-34	106	19	silp	silp	VERB
admet-34	106	20	p	p	PROPN
admet-34	106	21	p	p	X
admet-34	106	22	p	p	NOUN
admet-34	106	23	(	(	PUNCT
admet-34	106	24	7	7	NUM
admet-34	106	25	)	)	PUNCT
admet-34	106	26	*	*	PUNCT
admet-34	107	1	el	el	PROPN
admet-34	107	2	el	el	PROPN
admet-34	107	3	pk	pk	PROPN
admet-34	107	4	k	k	PROPN
admet-34	107	5	v	v	ADV
admet-34	107	6	*	*	PUNCT
admet-34	107	7	pt	pt	INTJ
admet-34	107	8	pt	pt	INTJ
admet-34	107	9	pk	pk	PROPN
admet-34	107	10	k	k	PROPN
admet-34	107	11	v	v	ADV
admet-34	107	12	*	*	PROPN
admet-34	107	13	tp	tp	PROPN
admet-34	107	14	tp	tp	PROPN
admet-34	107	15	pk	pk	PROPN
admet-34	107	16	k	k	PROPN
admet-34	107	17	v	v	ADV
admet-34	107	18	p	p	X
admet-34	107	19	tf	tf	X
admet-34	107	20	v	v	ADP
admet-34	107	21	v	v	ADV
admet-34	107	22	(	(	PUNCT
admet-34	107	23	8)	8)	NUM
admet-34	107	24	eq	eq	NOUN
admet-34	107	25	.	.	PUNCT
admet-34	108	1	(	(	PUNCT
admet-34	108	2	2	2	X
admet-34	108	3	)	)	PUNCT
admet-34	108	4	allows	allow	VERB
admet-34	108	5	the	the	DET
admet-34	108	6	computing	computing	NOUN
admet-34	108	7	of	of	ADP
admet-34	108	8	the	the	DET
admet-34	108	9	drug	drug	NOUN
admet-34	108	10	concentration	concentration	NOUN
admet-34	108	11	in	in	ADP
admet-34	108	12	the	the	DET
admet-34	108	13	gics	gic	NOUN
admet-34	108	14	,	,	PUNCT
admet-34	108	15	eq	eq	NOUN
admet-34	108	16	.	.	PUNCT
admet-34	109	1	(	(	PUNCT
admet-34	109	2	3	3	X
admet-34	109	3	)	)	PUNCT
admet-34	109	4	evaluates	evaluate	VERB
admet-34	109	5	the	the	DET
admet-34	109	6	liver	liver	NOUN
admet-34	109	7	drug	drug	NOUN
admet-34	109	8	concentration	concentration	NOUN
admet-34	109	9	,	,	PUNCT
admet-34	109	10	eq	eq	NOUN
admet-34	109	11	.	.	PUNCT
admet-34	110	1	(	(	PUNCT
admet-34	110	2	4	4	X
admet-34	110	3	)	)	PUNCT
admet-34	110	4	determines	determine	VERB
admet-34	110	5	the	the	DET
admet-34	110	6	evaluation	evaluation	NOUN
admet-34	110	7	of	of	ADP
admet-34	110	8	the	the	DET
admet-34	110	9	plasma	plasma	NOUN
admet-34	110	10	drug	drug	NOUN
admet-34	110	11	concentration	concentration	NOUN
admet-34	110	12	,	,	PUNCT
admet-34	110	13	eq	eq	NOUN
admet-34	110	14	.	.	PUNCT
admet-34	111	1	(	(	PUNCT
admet-34	111	2	5	5	X
admet-34	111	3	)	)	PUNCT
admet-34	111	4	calculates	calculate	VERB
admet-34	111	5	the	the	DET
admet-34	111	6	tissues	tissue	NOUN
admet-34	111	7	drug	drug	NOUN
admet-34	111	8	concentration	concentration	NOUN
admet-34	111	9	and	and	CCONJ
admet-34	111	10	,	,	PUNCT
admet-34	111	11	finally	finally	ADV
admet-34	111	12	,	,	PUNCT
admet-34	111	13	eq	eq	NOUN
admet-34	111	14	.	.	PUNCT
admet-34	112	1	(	(	PUNCT
admet-34	112	2	6	6	NUM
admet-34	112	3	)	)	PUNCT
admet-34	112	4	allows	allow	VERB
admet-34	112	5	calculation	calculation	NOUN
admet-34	112	6	of	of	ADP
admet-34	112	7	the	the	DET
admet-34	112	8	amount	amount	NOUN
admet-34	112	9	of	of	ADP
admet-34	112	10	drug	drug	NOUN
admet-34	112	11	eliminated	eliminate	VERB
admet-34	112	12	in	in	ADP
admet-34	112	13	the	the	DET
admet-34	112	14	release	release	NOUN
admet-34	112	15	environment	environment	NOUN
admet-34	112	16	,	,	PUNCT
admet-34	112	17	in	in	ADP
admet-34	112	18	the	the	DET
admet-34	112	19	liver	liver	NOUN
admet-34	112	20	,	,	PUNCT
admet-34	112	21	and	and	CCONJ
admet-34	112	22	in	in	ADP
admet-34	112	23	the	the	DET
admet-34	112	24	plasma	plasma	NOUN
admet-34	112	25	.	.	PUNCT
admet-34	113	1	inspection	inspection	NOUN
admet-34	113	2	of	of	ADP
admet-34	113	3	eq	eq	PROPN
admet-34	113	4	.	.	PUNCT
admet-34	114	1	(	(	PUNCT
admet-34	114	2	2	2	X
admet-34	114	3	)	)	PUNCT
admet-34	114	4	reveals	reveal	VERB
admet-34	114	5	that	that	SCONJ
admet-34	114	6	the	the	DET
admet-34	114	7	diffusive	diffusive	ADJ
admet-34	114	8	drug	drug	NOUN
admet-34	114	9	flux	flux	NOUN
admet-34	114	10	from	from	ADP
admet-34	114	11	the	the	DET
admet-34	114	12	release	release	NOUN
admet-34	114	13	environment	environment	NOUN
admet-34	114	14	to	to	ADP
admet-34	114	15	the	the	DET
admet-34	114	16	gics	gic	NOUN
admet-34	114	17	requires	require	VERB
admet-34	114	18	knowledge	knowledge	NOUN
admet-34	114	19	of	of	ADP
admet-34	114	20	the	the	DET
admet-34	114	21	drug	drug	NOUN
admet-34	114	22	concentration	concentration	NOUN
admet-34	114	23	in	in	ADP
admet-34	114	24	the	the	DET
admet-34	114	25	release	release	NOUN
admet-34	114	26	environment	environment	NOUN
admet-34	114	27	(	(	PUNCT
admet-34	114	28	cr	cr	NOUN
admet-34	114	29	)	)	PUNCT
admet-34	114	30	that	that	PRON
admet-34	114	31	is	be	AUX
admet-34	114	32	evaluated	evaluate	VERB
admet-34	114	33	in	in	ADP
admet-34	114	34	the	the	DET
admet-34	114	35	following	follow	VERB
admet-34	114	36	section	section	NOUN
admet-34	114	37	.	.	PUNCT
admet-34	115	1	delivery	delivery	NOUN
admet-34	115	2	model	model	NOUN
admet-34	115	3	briefly	briefly	ADV
admet-34	115	4	,	,	PUNCT
admet-34	115	5	our	our	PRON
admet-34	115	6	model	model	NOUN
admet-34	115	7	assumes	assume	VERB
admet-34	115	8	that	that	SCONJ
admet-34	115	9	the	the	DET
admet-34	115	10	drug	drug	NOUN
admet-34	115	11	release	release	NOUN
admet-34	115	12	kinetics	kinetic	NOUN
admet-34	115	13	are	be	AUX
admet-34	115	14	essentially	essentially	ADV
admet-34	115	15	determined	determine	VERB
admet-34	115	16	by	by	ADP
admet-34	115	17	(	(	PUNCT
admet-34	115	18	i	i	NOUN
admet-34	115	19	)	)	PUNCT
admet-34	115	20	polymeric	polymeric	ADJ
admet-34	115	21	particles	particle	NOUN
admet-34	115	22	size	size	NOUN
admet-34	115	23	distribution	distribution	NOUN
admet-34	115	24	in	in	ADP
admet-34	115	25	the	the	DET
admet-34	115	26	dry	dry	ADJ
admet-34	115	27	state	state	NOUN
admet-34	115	28	(	(	PUNCT
admet-34	115	29	ii	ii	NOUN
admet-34	115	30	)	)	PUNCT
admet-34	115	31	particle	particle	NOUN
admet-34	115	32	swelling	swell	VERB
admet-34	115	33	upon	upon	SCONJ
admet-34	115	34	contact	contact	NOUN
admet-34	115	35	with	with	ADP
admet-34	115	36	the	the	DET
admet-34	115	37	release	release	NOUN
admet-34	115	38	environment	environment	NOUN
admet-34	115	39	fluid	fluid	NOUN
admet-34	115	40	(	(	PUNCT
admet-34	115	41	solvent	solvent	NOUN
admet-34	115	42	)	)	PUNCT
admet-34	115	43	(	(	PUNCT
admet-34	115	44	particle	particle	NOUN
admet-34	115	45	erosion	erosion	NOUN
admet-34	115	46	is	be	AUX
admet-34	115	47	considered	consider	VERB
admet-34	115	48	negligible	negligible	ADJ
admet-34	115	49	,	,	PUNCT
admet-34	115	50	this	this	PRON
admet-34	115	51	being	be	AUX
admet-34	115	52	true	true	ADJ
admet-34	115	53	for	for	ADP
admet-34	115	54	highly	highly	ADV
admet-34	115	55	crosslinked	crosslinke	VERB
admet-34	115	56	polymeric	polymeric	ADJ
admet-34	115	57	networks	network	NOUN
admet-34	115	58	)	)	PUNCT
admet-34	115	59	(	(	PUNCT
admet-34	115	60	iii	iii	X
admet-34	115	61	)	)	PUNCT
admet-34	115	62	drug	drug	NOUN
admet-34	115	63	dissolution	dissolution	NOUN
admet-34	115	64	and	and	CCONJ
admet-34	115	65	diffusion	diffusion	NOUN
admet-34	115	66	inside	inside	ADP
admet-34	115	67	particles	particle	NOUN
admet-34	115	68	and	and	CCONJ
admet-34	115	69	(	(	PUNCT
admet-34	115	70	iv	iv	X
admet-34	115	71	)	)	PUNCT
admet-34	115	72	possible	possible	ADJ
admet-34	115	73	drug	drug	NOUN
admet-34	115	74	re	re	NOUN
admet-34	115	75	-	-	NOUN
admet-34	115	76	crystallisation	crystallisation	NOUN
admet-34	115	77	upon	upon	SCONJ
admet-34	115	78	contact	contact	NOUN
admet-34	115	79	with	with	ADP
admet-34	115	80	the	the	DET
admet-34	115	81	release	release	NOUN
admet-34	115	82	environment	environment	NOUN
admet-34	115	83	fluid	fluid	NOUN
admet-34	115	84	.	.	PUNCT
admet-34	116	1	the	the	DET
admet-34	116	2	first	first	ADJ
admet-34	116	3	point	point	NOUN
admet-34	116	4	is	be	AUX
admet-34	116	5	achieved	achieve	VERB
admet-34	116	6	by	by	ADP
admet-34	116	7	assuming	assume	VERB
admet-34	116	8	that	that	SCONJ
admet-34	116	9	dry	dry	ADJ
admet-34	116	10	particle	particle	NOUN
admet-34	116	11	size	size	NOUN
admet-34	116	12	distribution	distribution	NOUN
admet-34	116	13	can	can	AUX
admet-34	116	14	be	be	AUX
admet-34	116	15	conveniently	conveniently	ADV
admet-34	116	16	represented	represent	VERB
admet-34	116	17	by	by	ADP
admet-34	116	18	a	a	DET
admet-34	116	19	weibull	weibull	NOUN
admet-34	116	20	distribution	distribution	NOUN
admet-34	116	21	function	function	NOUN
admet-34	116	22	[	[	X
admet-34	116	23	16	16	NUM
admet-34	116	24	]	]	X
admet-34	116	25	:	:	PUNCT
admet-34	116	26	admet	admet	PROPN
admet-34	116	27	&	&	CCONJ
admet-34	116	28	dmpk	dmpk	PROPN
admet-34	116	29	2(2	2(2	NUM
admet-34	116	30	)	)	PUNCT
admet-34	116	31	(	(	PUNCT
admet-34	116	32	2014	2014	NUM
admet-34	116	33	)	)	PUNCT
admet-34	116	34	80	80	NUM
admet-34	116	35	-	-	SYM
admet-34	116	36	97	97	NUM
admet-34	116	37	in	in	ADP
admet-34	116	38	vivo	vivo	ADJ
admet-34	116	39	drug	drug	NOUN
admet-34	116	40	release	release	NOUN
admet-34	116	41	and	and	CCONJ
admet-34	116	42	absorption	absorption	NOUN
admet-34	116	43	doi	doi	NOUN
admet-34	116	44	:	:	PUNCT
admet-34	116	45	10.5599	10.5599	NUM
admet-34	116	46	/	/	SYM
admet-34	116	47	admet.2.2.34	admet.2.2.34	ADP
admet-34	116	48	85	85	NUM
admet-34	116	49	p	p	NOUN
admet-34	116	50	min	min	NOUN
admet-34	116	51	2	2	NUM
admet-34	116	52	0	0	NUM
admet-34	116	53	1	1	NUM
admet-34	116	54	e	e	NOUN
admet-34	116	55	r	r	NOUN
admet-34	116	56	r	r	NOUN
admet-34	116	57	v	v	NOUN
admet-34	116	58	v	v	ADP
admet-34	116	59			NUM
admet-34	116	60			PRON
admet-34	116	61			PROPN
admet-34	116	62			PROPN
admet-34	116	63			NOUN
admet-34	116	64			PROPN
admet-34	116	65			PROPN
admet-34	116	66			PROPN
admet-34	117	1			INTJ
admet-34	117	2			X
admet-34	118	1			VERB
admet-34	118	2			NOUN
admet-34	118	3			PROPN
admet-34	118	4			NOUN
admet-34	118	5	(	(	PUNCT
admet-34	118	6	9	9	NUM
admet-34	118	7	)	)	PUNCT
admet-34	118	8	where	where	SCONJ
admet-34	118	9	rp	rp	NOUN
admet-34	118	10	and	and	CCONJ
admet-34	118	11	rmin	rmin	NOUN
admet-34	118	12	are	be	AUX
admet-34	118	13	,	,	PUNCT
admet-34	118	14	respectively	respectively	ADV
admet-34	118	15	,	,	PUNCT
admet-34	118	16	the	the	DET
admet-34	118	17	generic	generic	ADJ
admet-34	118	18	particle	particle	NOUN
admet-34	118	19	radius	radius	NOUN
admet-34	118	20	and	and	CCONJ
admet-34	118	21	the	the	DET
admet-34	118	22	minimum	minimum	ADJ
admet-34	118	23	particle	particle	NOUN
admet-34	118	24	radius	radius	NOUN
admet-34	118	25	,	,	PUNCT
admet-34	118	26			PUNCT
admet-34	118	27	and	and	CCONJ
admet-34	118	28			NUM
admet-34	118	29	are	be	AUX
admet-34	118	30	two	two	NUM
admet-34	118	31	parameters	parameter	NOUN
admet-34	118	32	regulating	regulate	VERB
admet-34	118	33	the	the	DET
admet-34	118	34	weibull	weibull	NOUN
admet-34	118	35	size	size	NOUN
admet-34	118	36	distribution	distribution	NOUN
admet-34	118	37	,	,	PUNCT
admet-34	118	38	while	while	SCONJ
admet-34	118	39	v0	v0	NOUN
admet-34	118	40	and	and	CCONJ
admet-34	118	41	v	v	ADP
admet-34	118	42	arethe	arethe	ADJ
admet-34	118	43	total	total	ADJ
admet-34	118	44	volume	volume	NOUN
admet-34	118	45	occupied	occupy	VERB
admet-34	118	46	by	by	ADP
admet-34	118	47	the	the	DET
admet-34	118	48	ensemble	ensemble	NOUN
admet-34	118	49	of	of	ADP
admet-34	118	50	polymeric	polymeric	ADJ
admet-34	118	51	particles	particle	NOUN
admet-34	118	52	and	and	CCONJ
admet-34	118	53	the	the	DET
admet-34	118	54	volume	volume	NOUN
admet-34	118	55	occupied	occupy	VERB
admet-34	118	56	by	by	ADP
admet-34	118	57	particles	particle	NOUN
admet-34	118	58	having	have	VERB
admet-34	118	59	a	a	DET
admet-34	118	60	radius	radius	NOUN
admet-34	118	61	lower	low	ADJ
admet-34	118	62	than	than	ADP
admet-34	118	63	or	or	CCONJ
admet-34	118	64	equal	equal	ADJ
admet-34	118	65	to	to	ADP
admet-34	118	66	rp	rp	NOUN
admet-34	118	67	,	,	PUNCT
admet-34	118	68	respectively	respectively	ADV
admet-34	118	69	.	.	PUNCT
admet-34	119	1	in	in	ADP
admet-34	119	2	order	order	NOUN
admet-34	119	3	to	to	PART
admet-34	119	4	account	account	VERB
admet-34	119	5	for	for	ADP
admet-34	119	6	particles	particle	NOUN
admet-34	119	7	polydispersity	polydispersity	NOUN
admet-34	119	8	,	,	PUNCT
admet-34	119	9	the	the	DET
admet-34	119	10	weibull	weibull	NOUN
admet-34	119	11	size	size	NOUN
admet-34	119	12	distribution	distribution	NOUN
admet-34	119	13	(	(	PUNCT
admet-34	119	14	eq	eq	NOUN
admet-34	119	15	.	.	PUNCT
admet-34	119	16	(	(	PUNCT
admet-34	119	17	9	9	NUM
admet-34	119	18	)	)	PUNCT
admet-34	119	19	)	)	PUNCT
admet-34	119	20	is	be	AUX
admet-34	119	21	subdivided	subdivide	VERB
admet-34	119	22	into	into	ADP
admet-34	119	23	nc	nc	PROPN
admet-34	119	24	classes	classes	PROPN
admet-34	119	25	(	(	PUNCT
admet-34	119	26	from	from	ADP
admet-34	119	27	i	i	PRON
admet-34	119	28	=	=	NOUN
admet-34	119	29	1	1	NUM
admet-34	119	30	to	to	PART
admet-34	119	31	nc	nc	PROPN
admet-34	119	32	)	)	PUNCT
admet-34	119	33	on	on	ADP
admet-34	119	34	the	the	DET
admet-34	119	35	basis	basis	NOUN
admet-34	119	36	of	of	ADP
admet-34	119	37	the	the	DET
admet-34	119	38	particles	particle	NOUN
admet-34	119	39	radius	radius	NOUN
admet-34	119	40	.	.	PUNCT
admet-34	120	1	accordingly	accordingly	ADV
admet-34	120	2	,	,	PUNCT
admet-34	120	3	particles	particle	NOUN
admet-34	120	4	of	of	ADP
admet-34	120	5	class	class	NOUN
admet-34	121	1	i	i	PRON
admet-34	121	2	th	th	AUX
admet-34	121	3	share	share	VERB
admet-34	121	4	the	the	DET
admet-34	121	5	same	same	ADJ
admet-34	121	6	radius	radius	NOUN
admet-34	121	7	rpi	rpi	NOUN
admet-34	121	8	.	.	PUNCT
admet-34	122	1	for	for	ADP
admet-34	122	2	each	each	DET
admet-34	122	3	class	class	NOUN
admet-34	122	4	,	,	PUNCT
admet-34	122	5	the	the	DET
admet-34	122	6	swelling	swell	VERB
admet-34	122	7	process	process	NOUN
admet-34	122	8	can	can	AUX
admet-34	122	9	be	be	AUX
admet-34	122	10	evaluated	evaluate	VERB
admet-34	122	11	by	by	ADP
admet-34	122	12	the	the	DET
admet-34	122	13	following	follow	VERB
admet-34	122	14	mass	mass	NOUN
admet-34	122	15	balance	balance	NOUN
admet-34	122	16	referred	refer	VERB
admet-34	122	17	to	to	ADP
admet-34	122	18	the	the	DET
admet-34	122	19	swelling	swell	VERB
admet-34	122	20	agent	agent	NOUN
admet-34	122	21	(	(	PUNCT
admet-34	122	22	solvent	solvent	NOUN
admet-34	122	23	):	):	PUNCT
admet-34	122	24	pi	pi	NOUN
admet-34	122	25	2	2	NUM
admet-34	122	26	i	i	NOUN
admet-34	122	27	i2	i2	NOUN
admet-34	123	1	i	i	PRON
admet-34	123	2	i	i	PRON
admet-34	123	3	1c	1c	VERB
admet-34	123	4	r	r	NOUN
admet-34	123	5	j	j	PROPN
admet-34	123	6	t	t	NOUN
admet-34	123	7	r	r	NOUN
admet-34	123	8	r	r	NOUN
admet-34	123	9			ADJ
admet-34	123	10			ADJ
admet-34	123	11			PROPN
admet-34	123	12			PROPN
admet-34	123	13			PROPN
admet-34	123	14			VERB
admet-34	123	15			PROPN
admet-34	123	16			ADJ
admet-34	123	17	(	(	PUNCT
admet-34	123	18	10	10	NUM
admet-34	123	19	)	)	PUNCT
admet-34	123	20	rifii	rifii	NOUN
admet-34	123	21	jjj	jjj	PROPN
admet-34	124	1			PROPN
admet-34	124	2	,	,	PUNCT
admet-34	124	3	pi	pi	NOUN
admet-34	124	4	fi	fi	NOUN
admet-34	124	5	0	0	PUNCT
admet-34	125	1	i	i	PRON
admet-34	125	2	c	c	VERB
admet-34	125	3	j	j	PROPN
admet-34	126	1	d	d	NOUN
admet-34	126	2	r	r	NOUN
admet-34	126	3			ADJ
admet-34	126	4			PROPN
admet-34	126	5			PROPN
admet-34	126	6			PROPN
admet-34	126	7	,	,	PUNCT
admet-34	126	8	pi	pi	PROPN
admet-34	126	9	ri	ri	PROPN
admet-34	126	10	ri	ri	INTJ
admet-34	127	1	r	r	NOUN
admet-34	127	2	i	i	PRON
admet-34	127	3	τ	τ	PROPN
admet-34	128	1	c	c	PROPN
admet-34	128	2	j	j	PROPN
admet-34	129	1	j	j	PROPN
admet-34	129	2	d	d	PROPN
admet-34	129	3	r	r	NOUN
admet-34	129	4	t	t	PROPN
admet-34	129	5			ADJ
admet-34	129	6			PROPN
admet-34	129	7			PROPN
admet-34	129	8			PROPN
admet-34	129	9			PROPN
admet-34	129	10			ADJ
admet-34	129	11			NOUN
admet-34	129	12	(	(	PUNCT
admet-34	129	13	11	11	NUM
admet-34	129	14	)	)	PUNCT
admet-34	129	15	where	where	SCONJ
admet-34	129	16	jfi	jfi	PROPN
admet-34	129	17	and	and	CCONJ
admet-34	129	18	jri	jri	PROPN
admet-34	129	19	indicate	indicate	VERB
admet-34	129	20	the	the	DET
admet-34	129	21	fickian	fickian	ADJ
admet-34	129	22	and	and	CCONJ
admet-34	129	23	nonfickian	nonfickian	ADJ
admet-34	129	24	component	component	NOUN
admet-34	129	25	of	of	ADP
admet-34	129	26	the	the	DET
admet-34	129	27	solvent	solvent	NOUN
admet-34	129	28	flux	flux	NOUN
admet-34	129	29	,	,	PUNCT
admet-34	129	30	respectively	respectively	ADV
admet-34	129	31	.	.	PUNCT
admet-34	130	1	jri	jri	PROPN
admet-34	130	2	represents	represent	VERB
admet-34	130	3	a	a	DET
admet-34	130	4	delayed	delay	VERB
admet-34	130	5	flux	flux	NOUN
admet-34	130	6	induced	induce	VERB
admet-34	130	7	by	by	ADP
admet-34	130	8	the	the	DET
admet-34	130	9	polymer	polymer	NOUN
admet-34	130	10	/	/	SYM
admet-34	130	11	solvent	solvent	ADJ
admet-34	130	12	viscoelastic	viscoelastic	NOUN
admet-34	130	13	character	character	NOUN
admet-34	130	14	.	.	PUNCT
admet-34	131	1	d0	d0	PROPN
admet-34	131	2	and	and	CCONJ
admet-34	131	3	dr	dr	PROPN
admet-34	131	4	are	be	AUX
admet-34	131	5	,	,	PUNCT
admet-34	131	6	the	the	DET
admet-34	131	7	fickian	fickian	NOUN
admet-34	131	8	and	and	CCONJ
admet-34	131	9	the	the	DET
admet-34	131	10	non	non	ADJ
admet-34	131	11	-	-	ADJ
admet-34	131	12	fickian	fickian	ADJ
admet-34	131	13	solvent	solvent	NOUN
admet-34	131	14	diffusion	diffusion	NOUN
admet-34	131	15	coefficient	coefficient	NOUN
admet-34	131	16	,	,	PUNCT
admet-34	131	17	respectively	respectively	ADV
admet-34	131	18	,	,	PUNCT
admet-34	131	19	while	while	SCONJ
admet-34	131	20			NOUN
admet-34	131	21	is	be	AUX
admet-34	131	22	the	the	DET
admet-34	131	23	polymer	polymer	NOUN
admet-34	131	24	-	-	PUNCT
admet-34	131	25	solvent	solvent	NOUN
admet-34	131	26	relaxation	relaxation	NOUN
admet-34	131	27	time	time	NOUN
admet-34	131	28	:	:	PUNCT
admet-34	132	1			PROPN
admet-34	132	2	pi	pi	NOUN
admet-34	132	3	peq	peq	PROPN
admet-34	132	4	r	r	PROPN
admet-34	132	5	eq	eq	NOUN
admet-34	132	6	0	0	NUM
admet-34	132	7	g	g	NOUN
admet-34	132	8	c	c	NOUN
admet-34	132	9	c	c	NOUN
admet-34	132	10	d	d	X
admet-34	132	11	d	d	X
admet-34	132	12	e	e	X
admet-34	132	13	d	d	X
admet-34	132	14			VERB
admet-34	132	15			PROPN
admet-34	132	16			PRON
admet-34	132	17			PROPN
admet-34	132	18			PROPN
admet-34	132	19			ADJ
admet-34	132	20	pipeq	pipeq	NOUN
admet-34	132	21	eq	eq	NOUN
admet-34	132	22	ccf	ccf	PROPN
admet-34	132	23	e	e	PROPN
admet-34	132	24			PROPN
admet-34	132	25			NUM
admet-34	132	26	(	(	PUNCT
admet-34	132	27	12	12	NUM
admet-34	132	28	)	)	PUNCT
admet-34	132	29	where	where	SCONJ
admet-34	132	30	cpeq	cpeq	NOUN
admet-34	132	31	is	be	AUX
admet-34	132	32	the	the	DET
admet-34	132	33	solvent	solvent	ADJ
admet-34	132	34	concentration	concentration	NOUN
admet-34	132	35	in	in	ADP
admet-34	132	36	the	the	DET
admet-34	132	37	completely	completely	ADV
admet-34	132	38	swollen	swollen	ADJ
admet-34	132	39	polymeric	polymeric	ADJ
admet-34	132	40	network	network	NOUN
admet-34	132	41	(	(	PUNCT
admet-34	132	42	thermodynamic	thermodynamic	ADJ
admet-34	132	43	equilibrium	equilibrium	NOUN
admet-34	132	44	)	)	PUNCT
admet-34	132	45	,	,	PUNCT
admet-34	132	46	eq	eq	NOUN
admet-34	132	47	and	and	CCONJ
admet-34	132	48	deq	deq	PROPN
admet-34	132	49	are	be	AUX
admet-34	132	50	,	,	PUNCT
admet-34	132	51	respectively	respectively	ADV
admet-34	132	52	,	,	PUNCT
admet-34	132	53	the	the	DET
admet-34	132	54	relaxation	relaxation	NOUN
admet-34	132	55	time	time	NOUN
admet-34	132	56	and	and	CCONJ
admet-34	132	57	the	the	DET
admet-34	132	58	solvent	solvent	ADJ
admet-34	132	59	diffusion	diffusion	NOUN
admet-34	132	60	coefficient	coefficient	NOUN
admet-34	132	61	in	in	ADP
admet-34	132	62	equilibrium	equilibrium	NOUN
admet-34	132	63	conditions	condition	NOUN
admet-34	132	64	while	while	SCONJ
admet-34	132	65	g	g	PROPN
admet-34	132	66	and	and	CCONJ
admet-34	132	67	f	f	PROPN
admet-34	132	68	are	be	AUX
admet-34	132	69	two	two	NUM
admet-34	132	70	model	model	NOUN
admet-34	132	71	parameters	parameter	NOUN
admet-34	132	72	evaluated	evaluate	VERB
admet-34	132	73	in	in	ADP
admet-34	132	74	[	[	X
admet-34	132	75	11	11	NUM
admet-34	132	76	]	]	PUNCT
admet-34	132	77	by	by	ADP
admet-34	132	78	data	datum	NOUN
admet-34	132	79	fitting	fitting	ADJ
admet-34	132	80	.	.	PUNCT
admet-34	133	1	the	the	DET
admet-34	133	2	existence	existence	NOUN
admet-34	133	3	of	of	ADP
admet-34	133	4	two	two	NUM
admet-34	133	5	contributions	contribution	NOUN
admet-34	133	6	in	in	ADP
admet-34	133	7	the	the	DET
admet-34	133	8	solvent	solvent	NOUN
admet-34	133	9	flux	flux	NOUN
admet-34	133	10	is	be	AUX
admet-34	133	11	motivated	motivate	VERB
admet-34	133	12	by	by	ADP
admet-34	133	13	the	the	DET
admet-34	133	14	fact	fact	NOUN
admet-34	133	15	that	that	SCONJ
admet-34	133	16	the	the	DET
admet-34	133	17	“	"	PUNCT
admet-34	133	18	polymer	polymer	NOUN
admet-34	133	19	+	+	CCONJ
admet-34	133	20	solvent	solvent	NOUN
admet-34	133	21	”	"	PUNCT
admet-34	133	22	system	system	NOUN
admet-34	133	23	is	be	AUX
admet-34	133	24	viscoelastic	viscoelastic	ADJ
admet-34	133	25	,	,	PUNCT
admet-34	133	26	i.e.	i.e.	X
admet-34	133	27	polymeric	polymeric	ADJ
admet-34	133	28	chains	chain	NOUN
admet-34	133	29	undergo	undergo	VERB
admet-34	133	30	rearrangements	rearrangement	NOUN
admet-34	133	31	that	that	PRON
admet-34	133	32	develop	develop	VERB
admet-34	133	33	with	with	ADP
admet-34	133	34	time	time	NOUN
admet-34	133	35	(	(	PUNCT
admet-34	133	36	relaxation	relaxation	NOUN
admet-34	133	37	)	)	PUNCT
admet-34	133	38	upon	upon	SCONJ
admet-34	133	39	solvent	solvent	NOUN
admet-34	133	40	uptake	uptake	NOUN
admet-34	133	41	.	.	PUNCT
admet-34	134	1	in	in	ADP
admet-34	134	2	order	order	NOUN
admet-34	134	3	to	to	PART
admet-34	134	4	account	account	VERB
admet-34	134	5	for	for	ADP
admet-34	134	6	this	this	DET
admet-34	134	7	phenomenon	phenomenon	NOUN
admet-34	134	8	,	,	PUNCT
admet-34	134	9	camera	camera	NOUN
admet-34	134	10	-	-	PUNCT
admet-34	134	11	roda	roda	NOUN
admet-34	134	12	and	and	CCONJ
admet-34	134	13	sarti	sarti	PROPN
admet-34	134	14	successfully	successfully	ADV
admet-34	134	15	proposed	propose	VERB
admet-34	134	16	the	the	DET
admet-34	134	17	approach	approach	NOUN
admet-34	134	18	expressed	express	VERB
admet-34	134	19	by	by	ADP
admet-34	134	20	eq	eq	PROPN
admet-34	134	21	.	.	PUNCT
admet-34	135	1	(	(	PUNCT
admet-34	135	2	11	11	NUM
admet-34	135	3	)	)	PUNCT
admet-34	136	1	[	[	X
admet-34	136	2	17	17	NUM
admet-34	136	3	]	]	PUNCT
admet-34	136	4	.	.	PUNCT
admet-34	137	1	eq	eq	X
admet-34	137	2	.	.	PUNCT
admet-34	138	1	(	(	PUNCT
admet-34	138	2	10	10	NUM
admet-34	138	3	)	)	PUNCT
admet-34	138	4	can	can	AUX
admet-34	138	5	be	be	AUX
admet-34	138	6	solved	solve	VERB
admet-34	138	7	assuming	assume	VERB
admet-34	138	8	that	that	SCONJ
admet-34	138	9	,	,	PUNCT
admet-34	138	10	initially	initially	ADV
admet-34	138	11	,	,	PUNCT
admet-34	138	12	particles	particle	NOUN
admet-34	138	13	are	be	AUX
admet-34	138	14	solvent	solvent	ADJ
admet-34	138	15	-	-	PUNCT
admet-34	138	16	free	free	ADJ
admet-34	138	17	,	,	PUNCT
admet-34	138	18	that	that	DET
admet-34	138	19	solvent	solvent	ADJ
admet-34	138	20	flux	flux	NOUN
admet-34	138	21	,	,	PUNCT
admet-34	138	22	for	for	ADP
admet-34	138	23	symmetry	symmetry	NOUN
admet-34	138	24	reasons	reason	NOUN
admet-34	138	25	,	,	PUNCT
admet-34	138	26	is	be	AUX
admet-34	138	27	zero	zero	NUM
admet-34	138	28	in	in	ADP
admet-34	138	29	the	the	DET
admet-34	138	30	particle	particle	NOUN
admet-34	138	31	centre	centre	NOUN
admet-34	138	32	and	and	CCONJ
admet-34	138	33	that	that	SCONJ
admet-34	138	34	solvent	solvent	ADJ
admet-34	138	35	concentration	concentration	NOUN
admet-34	138	36	at	at	ADP
admet-34	138	37	the	the	DET
admet-34	138	38	particle	particle	NOUN
admet-34	138	39	surface	surface	NOUN
admet-34	138	40	(	(	PUNCT
admet-34	138	41	cpint	cpint	NOUN
admet-34	138	42	)	)	PUNCT
admet-34	138	43	is	be	AUX
admet-34	138	44	defined	define	VERB
admet-34	138	45	by	by	ADP
admet-34	138	46	:	:	PUNCT
admet-34	138	47			PROPN
admet-34	139	1			PROPN
admet-34	139	2			NOUN
admet-34	139	3			SYM
admet-34	139	4			NOUN
admet-34	139	5			PROPN
admet-34	139	6	pint	pint	NOUN
admet-34	139	7	pint	pint	NOUN
admet-34	139	8	peq	peq	PROPN
admet-34	139	9	pint	pint	NOUN
admet-34	139	10	int	int	NOUN
admet-34	140	1	d	d	NOUN
admet-34	140	2	d	d	X
admet-34	140	3	c	c	NOUN
admet-34	140	4	t	t	NOUN
admet-34	140	5	c	c	NOUN
admet-34	140	6	c	c	PROPN
admet-34	140	7	c	c	PROPN
admet-34	140	8	t	t	PROPN
admet-34	140	9	t	t	PROPN
admet-34	140	10			PROPN
admet-34	140	11			PROPN
admet-34	140	12			NOUN
admet-34	140	13	(	(	PUNCT
admet-34	140	14	13	13	NUM
admet-34	140	15	)	)	PUNCT
admet-34	140	16	the	the	DET
admet-34	140	17	swelling	swell	VERB
admet-34	140	18	part	part	NOUN
admet-34	140	19	of	of	ADP
admet-34	140	20	this	this	DET
admet-34	140	21	model	model	NOUN
admet-34	140	22	is	be	AUX
admet-34	140	23	completed	complete	VERB
admet-34	140	24	by	by	ADP
admet-34	140	25	assuming	assume	VERB
admet-34	140	26	that	that	SCONJ
admet-34	140	27	the	the	DET
admet-34	140	28	solvent	solvent	ADJ
admet-34	140	29	-	-	PUNCT
admet-34	140	30	polymer	polymer	NOUN
admet-34	140	31	mixing	mixing	NOUN
admet-34	140	32	is	be	AUX
admet-34	140	33	ideal	ideal	ADJ
admet-34	140	34	,	,	PUNCT
admet-34	140	35	i.e.	i.e.	X
admet-34	140	36	,	,	PUNCT
admet-34	140	37	upon	upon	SCONJ
admet-34	140	38	swelling	swelling	NOUN
admet-34	140	39	,	,	PUNCT
admet-34	140	40	particle	particle	NOUN
admet-34	140	41	volume	volume	NOUN
admet-34	140	42	can	can	AUX
admet-34	140	43	be	be	AUX
admet-34	140	44	simply	simply	ADV
admet-34	140	45	computed	compute	VERB
admet-34	140	46	anytime	anytime	ADV
admet-34	140	47	by	by	ADP
admet-34	140	48	summing	sum	VERB
admet-34	140	49	polymer	polymer	NOUN
admet-34	140	50	and	and	CCONJ
admet-34	140	51	solvent	solvent	NOUN
admet-34	140	52	volume	volume	NOUN
admet-34	140	53	.	.	PUNCT
admet-34	141	1	inspection	inspection	NOUN
admet-34	141	2	of	of	ADP
admet-34	141	3	eqs	eqs	PROPN
admet-34	141	4	.	.	PUNCT
admet-34	142	1	(	(	PUNCT
admet-34	142	2	10	10	NUM
admet-34	142	3	)	)	PUNCT
admet-34	142	4	–	–	PUNCT
admet-34	142	5	(	(	PUNCT
admet-34	142	6	13	13	NUM
admet-34	142	7	)	)	PUNCT
admet-34	142	8	clearly	clearly	ADV
admet-34	142	9	reveals	reveal	VERB
admet-34	142	10	that	that	SCONJ
admet-34	142	11	solvent	solvent	ADJ
admet-34	142	12	diffusion	diffusion	NOUN
admet-34	142	13	is	be	AUX
admet-34	142	14	assumed	assume	VERB
admet-34	142	15	independent	independent	ADJ
admet-34	142	16	of	of	ADP
admet-34	142	17	the	the	DET
admet-34	142	18	presence	presence	NOUN
admet-34	142	19	of	of	ADP
admet-34	142	20	drug	drug	NOUN
admet-34	142	21	,	,	PUNCT
admet-34	142	22	this	this	PRON
admet-34	142	23	being	be	AUX
admet-34	142	24	rigorously	rigorously	ADV
admet-34	142	25	true	true	ADJ
admet-34	142	26	only	only	ADV
admet-34	142	27	for	for	ADP
admet-34	142	28	low	low	ADJ
admet-34	142	29	drug	drug	NOUN
admet-34	142	30	concentrations	concentration	NOUN
admet-34	142	31	in	in	ADP
admet-34	142	32	the	the	DET
admet-34	142	33	particles	particle	NOUN
admet-34	142	34	.	.	PUNCT
admet-34	143	1	drug	drug	NOUN
admet-34	143	2	transport	transport	NOUN
admet-34	143	3	in	in	ADP
admet-34	143	4	the	the	DET
admet-34	143	5	polymeric	polymeric	ADJ
admet-34	143	6	network	network	NOUN
admet-34	143	7	(	(	PUNCT
admet-34	143	8	point	point	NOUN
admet-34	143	9	iii	iii	NOUN
admet-34	143	10	)	)	PUNCT
admet-34	143	11	is	be	AUX
admet-34	143	12	modelled	model	VERB
admet-34	143	13	according	accord	VERB
admet-34	143	14	to	to	ADP
admet-34	143	15	the	the	DET
admet-34	143	16	following	following	ADJ
admet-34	143	17	equations	equation	NOUN
admet-34	143	18	:	:	PUNCT
admet-34	143	19	am	be	AUX
admet-34	143	20	nc	nc	PROPN
admet-34	143	21	mc	mc	PROPN
admet-34	143	22	2	2	NUM
admet-34	143	23	di	di	X
admet-34	143	24	di	di	X
admet-34	143	25	dii	dii	PROPN
admet-34	143	26	i	i	PROPN
admet-34	143	27	i2	i2	VERB
admet-34	144	1	i	i	PRON
admet-34	145	1	i	i	PRON
admet-34	146	1	i	i	VERB
admet-34	146	2	1	1	NUM
admet-34	147	1	c	c	NOUN
admet-34	147	2	c	c	NOUN
admet-34	147	3	cc	cc	NOUN
admet-34	147	4	c	c	PROPN
admet-34	148	1	d	d	NOUN
admet-34	148	2	r	r	NOUN
admet-34	148	3	t	t	PROPN
admet-34	148	4	t	t	PROPN
admet-34	148	5	t	t	PROPN
admet-34	148	6	tr	tr	NOUN
admet-34	148	7	r	r	NOUN
admet-34	148	8	r	r	NOUN
admet-34	148	9			ADJ
admet-34	148	10			PROPN
admet-34	148	11			PROPN
admet-34	148	12			PROPN
admet-34	148	13			PROPN
admet-34	148	14			PROPN
admet-34	148	15			PROPN
admet-34	148	16			VERB
admet-34	148	17			PUNCT
admet-34	148	18			ADJ
admet-34	148	19			PROPN
admet-34	148	20			PROPN
admet-34	148	21			PROPN
admet-34	148	22			PROPN
admet-34	148	23			NOUN
admet-34	148	24			ADV
admet-34	148	25			VERB
admet-34	148	26			PROPN
admet-34	148	27			PROPN
admet-34	148	28			PROPN
admet-34	149	1			PROPN
admet-34	150	1			PROPN
admet-34	150	2			PROPN
admet-34	150	3			PROPN
admet-34	150	4			PROPN
admet-34	150	5			NOUN
admet-34	150	6	(	(	PUNCT
admet-34	150	7	14	14	NUM
admet-34	150	8	)	)	PUNCT
admet-34	150	9	del	del	PROPN
admet-34	150	10	cont	cont	NOUN
admet-34	150	11	et	et	PROPN
admet-34	150	12	al	al	PROPN
admet-34	150	13	.	.	PROPN
admet-34	150	14	admet	admet	PROPN
admet-34	150	15	&	&	CCONJ
admet-34	150	16	dmpk	dmpk	PROPN
admet-34	150	17	2(2	2(2	NUM
admet-34	150	18	)	)	PUNCT
admet-34	150	19	(	(	PUNCT
admet-34	150	20	2014	2014	NUM
admet-34	150	21	)	)	PUNCT
admet-34	150	22	80	80	NUM
admet-34	150	23	-	-	SYM
admet-34	150	24	97	97	NUM
admet-34	150	25	86	86	NUM
admet-34	151	1	i	i	PRON
admet-34	151	2	i	i	PRON
admet-34	151	3	pi1	pi1	INTJ
admet-34	152	1	i	i	PRON
admet-34	152	2	ds	ds	VERB
admet-34	152	3	s	s	X
admet-34	152	4	,	,	PUNCT
admet-34	152	5	1	1	NUM
admet-34	152	6	ρ	ρ	NUM
admet-34	152	7	cd	cd	NOUN
admet-34	152	8	e	e	PROPN
admet-34	152	9	d	d	ADP
admet-34	152	10			NOUN
admet-34	152	11			NOUN
admet-34	152	12			NOUN
admet-34	152	13			PROPN
admet-34	152	14			PROPN
admet-34	152	15			NOUN
admet-34	152	16			PROPN
admet-34	152	17			PROPN
admet-34	152	18			PROPN
admet-34	153	1			ADJ
admet-34	153	2			PROPN
admet-34	153	3			NUM
admet-34	153	4			NOUN
admet-34	153	5	s	s	NOUN
admet-34	153	6	=	=	SYM
admet-34	153	7	1	1	NUM
admet-34	153	8	g	g	NOUN
admet-34	153	9	/	/	SYM
admet-34	153	10	cm	cm	NOUN
admet-34	153	11	3	3	NUM
admet-34	153	12	(	(	PUNCT
admet-34	153	13	15	15	NUM
admet-34	153	14	)	)	PUNCT
admet-34	153	15			PROPN
admet-34	153	16	am	am	NOUN
admet-34	154	1	amam	amam	PROPN
admet-34	154	2	s	s	VERB
admet-34	155	1	i	i	PRON
admet-34	155	2	didi	didi	NOUN
admet-34	155	3	am	be	AUX
admet-34	155	4	di	di	X
admet-34	155	5	0	0	NUM
admet-34	155	6	0	0	NUM
admet-34	155	7	0	0	NUM
admet-34	156	1	k	k	NOUN
admet-34	157	1	c	c	NOUN
admet-34	157	2	c	c	NOUN
admet-34	158	1	if	if	SCONJ
admet-34	158	2	cc	cc	PROPN
admet-34	158	3	t	t	PROPN
admet-34	158	4	if	if	SCONJ
admet-34	158	5	c	c	PROPN
admet-34	158	6			PROPN
admet-34	158	7			PROPN
admet-34	158	8			VERB
admet-34	159	1			NUM
admet-34	159	2			ADJ
admet-34	159	3			PRON
admet-34	159	4			PRON
admet-34	159	5			NUM
admet-34	159	6			NOUN
admet-34	159	7	(	(	PUNCT
admet-34	159	8	16	16	NUM
admet-34	159	9	)	)	PUNCT
admet-34	159	10			NOUN
admet-34	159	11			PROPN
admet-34	159	12	ram	ram	NOUN
admet-34	159	13	am	be	AUX
admet-34	159	14	mc	mc	PROPN
admet-34	159	15	mc	mc	PROPN
admet-34	159	16	s	s	PROPN
admet-34	160	1	s0	s0	PROPN
admet-34	160	2	s	s	PART
admet-34	160	3	s	s	X
admet-34	160	4	k	k	X
admet-34	160	5	t	t	NOUN
admet-34	160	6	c	c	NOUN
admet-34	160	7	c	c	NOUN
admet-34	160	8	c	c	NOUN
admet-34	160	9	e	e	X
admet-34	160	10	c	c	PROPN
admet-34	160	11			PROPN
admet-34	160	12			PROPN
admet-34	160	13			PROPN
admet-34	160	14			X
admet-34	160	15	(	(	PUNCT
admet-34	160	16	17	17	NUM
admet-34	160	17	)	)	PUNCT
admet-34	160	18			NOUN
admet-34	160	19	nc	nc	ADV
admet-34	160	20	ncnc	ncnc	PROPN
admet-34	160	21	s	s	VERB
admet-34	161	1	i	i	PRON
admet-34	161	2	didi	didi	PROPN
admet-34	161	3	nc	nc	PROPN
admet-34	161	4	di	di	PROPN
admet-34	161	5	0	0	PROPN
admet-34	161	6	0	0	NUM
admet-34	161	7	0	0	NUM
admet-34	162	1	k	k	NOUN
admet-34	163	1	c	c	NOUN
admet-34	163	2	c	c	NOUN
admet-34	164	1	if	if	SCONJ
admet-34	164	2	cc	cc	PROPN
admet-34	164	3	t	t	PROPN
admet-34	164	4	if	if	SCONJ
admet-34	164	5	c	c	PROPN
admet-34	164	6			PROPN
admet-34	164	7			PROPN
admet-34	164	8			VERB
admet-34	165	1			NUM
admet-34	165	2			ADJ
admet-34	165	3			PRON
admet-34	165	4			PRON
admet-34	165	5			NUM
admet-34	165	6			NOUN
admet-34	165	7	(	(	PUNCT
admet-34	165	8	18	18	NUM
admet-34	165	9	)	)	PUNCT
admet-34	165	10			PROPN
admet-34	165	11	mc	mc	PROPN
admet-34	166	1	mcmc	mcmc	PROPN
admet-34	166	2	s	s	PROPN
admet-34	167	1	i	i	PRON
admet-34	167	2	didi	didi	PROPN
admet-34	167	3	mc	mc	PROPN
admet-34	167	4	di	di	PROPN
admet-34	167	5	0	0	PROPN
admet-34	167	6	0	0	NUM
admet-34	167	7	0	0	NUM
admet-34	168	1	k	k	NOUN
admet-34	169	1	c	c	NOUN
admet-34	169	2	c	c	NOUN
admet-34	170	1	if	if	SCONJ
admet-34	170	2	cc	cc	PROPN
admet-34	170	3	t	t	PROPN
admet-34	170	4	if	if	SCONJ
admet-34	170	5	c	c	PROPN
admet-34	170	6			PROPN
admet-34	170	7			PROPN
admet-34	170	8			VERB
admet-34	171	1			NUM
admet-34	171	2			ADJ
admet-34	171	3			PRON
admet-34	171	4			PRON
admet-34	171	5			NUM
admet-34	171	6			NOUN
admet-34	171	7	(	(	PUNCT
admet-34	171	8	19	19	NUM
admet-34	171	9	)	)	PUNCT
admet-34	171	10			NOUN
admet-34	171	11	mcc	mcc	VERB
admet-34	171	12	r	r	NOUN
admet-34	171	13	rb	rb	NOUN
admet-34	171	14	r	r	NOUN
admet-34	171	15	sc	sc	PROPN
admet-34	171	16	d	d	X
admet-34	171	17	d	d	PROPN
admet-34	171	18	m	m	PROPN
admet-34	171	19	v	v	ADP
admet-34	171	20	k	k	PROPN
admet-34	171	21	c	c	NOUN
admet-34	171	22	c	c	PROPN
admet-34	171	23	t	t	PROPN
admet-34	171	24			PROPN
admet-34	171	25			PROPN
admet-34	171	26	(	(	PUNCT
admet-34	171	27	20	20	NUM
admet-34	171	28	)	)	PUNCT
admet-34	171	29	eq	eq	NOUN
admet-34	171	30	.	.	PUNCT
admet-34	172	1	(	(	PUNCT
admet-34	172	2	14	14	NUM
admet-34	172	3	)	)	PUNCT
admet-34	172	4	represents	represent	VERB
admet-34	172	5	the	the	DET
admet-34	172	6	drug	drug	NOUN
admet-34	172	7	mass	mass	NOUN
admet-34	172	8	balance	balance	NOUN
admet-34	172	9	relative	relative	ADJ
admet-34	172	10	to	to	ADP
admet-34	172	11	the	the	DET
admet-34	172	12	“	"	PUNCT
admet-34	172	13	ith	ith	PROPN
admet-34	172	14	”	"	PUNCT
admet-34	172	15	class	class	NOUN
admet-34	172	16	of	of	ADP
admet-34	172	17	particles	particle	NOUN
admet-34	172	18	,	,	PUNCT
admet-34	172	19	i.e.	i.e.	X
admet-34	172	20	the	the	DET
admet-34	172	21	class	class	NOUN
admet-34	172	22	of	of	ADP
admet-34	172	23	particles	particle	NOUN
admet-34	172	24	characterised	characterise	VERB
admet-34	172	25	by	by	ADP
admet-34	172	26	radius	radius	NOUN
admet-34	172	27	rpi	rpi	NOUN
admet-34	172	28	.	.	PUNCT
admet-34	173	1	this	this	DET
admet-34	173	2	equation	equation	NOUN
admet-34	173	3	implies	imply	VERB
admet-34	173	4	the	the	DET
admet-34	173	5	existence	existence	NOUN
admet-34	173	6	of	of	ADP
admet-34	173	7	dissolved	dissolved	ADJ
admet-34	173	8	and	and	CCONJ
admet-34	173	9	undissolved	undissolve	VERB
admet-34	173	10	drug	drug	NOUN
admet-34	173	11	inside	inside	ADP
admet-34	173	12	the	the	DET
admet-34	173	13	swelling	swell	VERB
admet-34	173	14	polymeric	polymeric	ADJ
admet-34	173	15	network	network	NOUN
admet-34	173	16	.	.	PUNCT
admet-34	174	1	while	while	SCONJ
admet-34	174	2	undissolved	undissolved	ADJ
admet-34	174	3	drug	drug	NOUN
admet-34	174	4	can	can	AUX
admet-34	174	5	not	not	PART
admet-34	174	6	move	move	VERB
admet-34	174	7	,	,	PUNCT
admet-34	174	8	dissolved	dissolve	VERB
admet-34	174	9	drug	drug	NOUN
admet-34	174	10	mobility	mobility	NOUN
admet-34	174	11	is	be	AUX
admet-34	174	12	controlled	control	VERB
admet-34	174	13	by	by	ADP
admet-34	174	14	its	its	PRON
admet-34	174	15	diffusion	diffusion	NOUN
admet-34	174	16	coefficient	coefficient	NOUN
admet-34	174	17	d	d	PROPN
admet-34	174	18	that	that	PRON
admet-34	174	19	depends	depend	VERB
admet-34	174	20	on	on	ADP
admet-34	174	21	the	the	DET
admet-34	174	22	local	local	ADJ
admet-34	174	23	solvent	solvent	ADJ
admet-34	174	24	concentration	concentration	NOUN
admet-34	174	25	cpi	cpi	NOUN
admet-34	174	26	according	accord	VERB
admet-34	174	27	to	to	ADP
admet-34	174	28	the	the	DET
admet-34	174	29	peppas	peppa	NOUN
admet-34	174	30	–	–	PUNCT
admet-34	174	31	reinhart	reinhart	NOUN
admet-34	174	32	theory	theory	NOUN
admet-34	174	33	[	[	X
admet-34	174	34	18	18	NUM
admet-34	174	35	]	]	PUNCT
admet-34	174	36	(	(	PUNCT
admet-34	174	37	see	see	VERB
admet-34	174	38	eq	eq	ADP
admet-34	174	39	.	.	PUNCT
admet-34	175	1	(	(	PUNCT
admet-34	175	2	15	15	NUM
admet-34	175	3	)	)	PUNCT
admet-34	175	4	)	)	PUNCT
admet-34	175	5	.	.	PUNCT
admet-34	176	1	in	in	ADP
admet-34	176	2	eq	eq	ADP
admet-34	176	3	.	.	PUNCT
admet-34	176	4	(	(	PUNCT
admet-34	176	5	15	15	NUM
admet-34	176	6	)	)	PUNCT
admet-34	176	7	,	,	PUNCT
admet-34	176	8	dds	dds	PROPN
admet-34	176	9	represents	represent	VERB
admet-34	176	10	the	the	DET
admet-34	176	11	drug	drug	NOUN
admet-34	176	12	diffusion	diffusion	NOUN
admet-34	176	13	coefficient	coefficient	NOUN
admet-34	176	14	in	in	ADP
admet-34	176	15	the	the	DET
admet-34	176	16	pure	pure	ADJ
admet-34	176	17	solvent	solvent	NOUN
admet-34	176	18	while	while	SCONJ
admet-34	176	19	i	i	NOUN
admet-34	176	20	is	be	AUX
admet-34	176	21	the	the	DET
admet-34	176	22	local	local	ADJ
admet-34	176	23	polymer	polymer	NOUN
admet-34	176	24	volume	volume	NOUN
admet-34	176	25	fraction	fraction	NOUN
admet-34	176	26	and	and	CCONJ
admet-34	176	27	s	s	NOUN
admet-34	176	28	indicates	indicate	VERB
admet-34	176	29	solvent	solvent	ADJ
admet-34	176	30	density	density	NOUN
admet-34	176	31	.	.	PUNCT
admet-34	177	1	while	while	SCONJ
admet-34	177	2	ci	ci	PROPN
admet-34	177	3	is	be	AUX
admet-34	177	4	the	the	DET
admet-34	177	5	position	position	NOUN
admet-34	177	6	-	-	PUNCT
admet-34	177	7	dependent	dependent	ADJ
admet-34	177	8	concentration	concentration	NOUN
admet-34	177	9	of	of	ADP
admet-34	177	10	the	the	DET
admet-34	177	11	dissolved	dissolve	VERB
admet-34	177	12	drug	drug	NOUN
admet-34	177	13	,	,	PUNCT
admet-34	177	14	am	be	AUX
admet-34	177	15	dic	dic	PROPN
admet-34	177	16	,	,	PUNCT
admet-34	177	17	nc	nc	PROPN
admet-34	177	18	dic	dic	PROPN
admet-34	177	19	and	and	CCONJ
admet-34	177	20	mc	mc	PROPN
admet-34	177	21	dic	dic	PROPN
admet-34	177	22	are	be	AUX
admet-34	177	23	,	,	PUNCT
admet-34	177	24	respectively	respectively	ADV
admet-34	177	25	,	,	PUNCT
admet-34	177	26	the	the	DET
admet-34	177	27	positiondependent	positiondependent	ADJ
admet-34	177	28	concentrations	concentration	NOUN
admet-34	177	29	of	of	ADP
admet-34	177	30	the	the	DET
admet-34	177	31	undissolved	undissolve	VERB
admet-34	177	32	drug	drug	NOUN
admet-34	177	33	in	in	ADP
admet-34	177	34	the	the	DET
admet-34	177	35	amorphous	amorphous	ADJ
admet-34	177	36	,	,	PUNCT
admet-34	177	37	nano	nano	NOUN
admet-34	177	38	-	-	PUNCT
admet-34	177	39	crystalline	crystalline	NOUN
admet-34	177	40	and	and	CCONJ
admet-34	177	41	microcrystalline	microcrystalline	NOUN
admet-34	177	42	state	state	NOUN
admet-34	177	43	.	.	PUNCT
admet-34	178	1	indeed	indeed	ADV
admet-34	178	2	,	,	PUNCT
admet-34	178	3	in	in	ADP
admet-34	178	4	polymeric	polymeric	ADJ
admet-34	178	5	matrices	matrix	NOUN
admet-34	178	6	,	,	PUNCT
admet-34	178	7	depending	depend	VERB
admet-34	178	8	on	on	ADP
admet-34	178	9	the	the	DET
admet-34	178	10	drug	drug	NOUN
admet-34	178	11	loading	loading	NOUN
admet-34	178	12	technique	technique	NOUN
admet-34	178	13	adopted	adopt	VERB
admet-34	178	14	,	,	PUNCT
admet-34	178	15	the	the	DET
admet-34	178	16	drug	drug	NOUN
admet-34	178	17	can	can	AUX
admet-34	178	18	be	be	AUX
admet-34	178	19	found	find	VERB
admet-34	178	20	in	in	ADP
admet-34	178	21	amorphous	amorphous	ADJ
admet-34	178	22	,	,	PUNCT
admet-34	178	23	nanocrystalline	nanocrystalline	ADJ
admet-34	178	24	and	and	CCONJ
admet-34	178	25	microcrystalline	microcrystalline	NOUN
admet-34	178	26	state	state	NOUN
admet-34	178	27	[	[	X
admet-34	178	28	16	16	NUM
admet-34	178	29	]	]	PUNCT
admet-34	178	30	.	.	PUNCT
admet-34	179	1	as	as	SCONJ
admet-34	179	2	nano	nano	NOUN
admet-34	179	3	-	-	NOUN
admet-34	179	4	crystals	crystal	NOUN
admet-34	179	5	and	and	CCONJ
admet-34	179	6	amorphous	amorphous	ADJ
admet-34	179	7	drug	drug	NOUN
admet-34	179	8	are	be	AUX
admet-34	179	9	characterised	characterise	VERB
admet-34	179	10	by	by	ADP
admet-34	179	11	a	a	DET
admet-34	179	12	higher	high	ADJ
admet-34	179	13	solubility	solubility	NOUN
admet-34	179	14	with	with	ADP
admet-34	179	15	respect	respect	NOUN
admet-34	179	16	to	to	ADP
admet-34	179	17	that	that	PRON
admet-34	179	18	of	of	ADP
admet-34	179	19	microcrystals	microcrystal	NOUN
admet-34	179	20	[	[	X
admet-34	179	21	19	19	NUM
admet-34	179	22	]	]	PUNCT
admet-34	179	23	,	,	PUNCT
admet-34	179	24	their	their	PRON
admet-34	179	25	presence	presence	NOUN
admet-34	179	26	can	can	AUX
admet-34	179	27	have	have	VERB
admet-34	179	28	a	a	DET
admet-34	179	29	significant	significant	ADJ
admet-34	179	30	effect	effect	NOUN
admet-34	179	31	upon	upon	SCONJ
admet-34	179	32	drug	drug	NOUN
admet-34	179	33	bioavailability	bioavailability	NOUN
admet-34	179	34	.	.	PUNCT
admet-34	180	1	whatever	whatever	PRON
admet-34	180	2	the	the	DET
admet-34	180	3	state	state	NOUN
admet-34	180	4	is	be	AUX
admet-34	180	5	,	,	PUNCT
admet-34	180	6	the	the	DET
admet-34	180	7	drug	drug	NOUN
admet-34	180	8	dissolution	dissolution	NOUN
admet-34	180	9	rate	rate	NOUN
admet-34	180	10	(	(	PUNCT
admet-34	180	11	eqs	eqs	X
admet-34	180	12	.	.	PUNCT
admet-34	181	1	(	(	PUNCT
admet-34	181	2	16	16	NUM
admet-34	181	3	)	)	PUNCT
admet-34	181	4	,	,	PUNCT
admet-34	181	5	(	(	PUNCT
admet-34	181	6	18	18	NUM
admet-34	181	7	)	)	PUNCT
admet-34	181	8	,	,	PUNCT
admet-34	181	9	(	(	PUNCT
admet-34	181	10	19	19	NUM
admet-34	181	11	)	)	PUNCT
admet-34	181	12	)	)	PUNCT
admet-34	181	13	is	be	AUX
admet-34	181	14	assumed	assume	VERB
admet-34	181	15	to	to	PART
admet-34	181	16	be	be	AUX
admet-34	181	17	proportional	proportional	ADJ
admet-34	181	18	(	(	PUNCT
admet-34	181	19	k	k	X
admet-34	181	20	being	be	AUX
admet-34	181	21	the	the	DET
admet-34	181	22	proportionality	proportionality	NOUN
admet-34	181	23	constant	constant	ADJ
admet-34	181	24	)	)	PUNCT
admet-34	181	25	to	to	ADP
admet-34	181	26	the	the	DET
admet-34	181	27	difference	difference	NOUN
admet-34	181	28	between	between	ADP
admet-34	181	29	the	the	DET
admet-34	181	30	local	local	ADJ
admet-34	181	31	drug	drug	NOUN
admet-34	181	32	concentration	concentration	NOUN
admet-34	181	33	ci	ci	NOUN
admet-34	181	34	and	and	CCONJ
admet-34	181	35	drug	drug	NOUN
admet-34	181	36	solubility	solubility	NOUN
admet-34	181	37	(	(	PUNCT
admet-34	181	38	am	be	AUX
admet-34	181	39	sc	sc	PROPN
admet-34	181	40	,	,	PUNCT
admet-34	181	41	nc	nc	PROPN
admet-34	181	42	sc	sc	PROPN
admet-34	181	43	,	,	PUNCT
admet-34	181	44	mc	mc	PROPN
admet-34	181	45	sc	sc	PROPN
admet-34	181	46	for	for	ADP
admet-34	181	47	amorphous	amorphous	ADJ
admet-34	181	48	,	,	PUNCT
admet-34	181	49	nanocrystal	nanocrystal	ADJ
admet-34	181	50	and	and	CCONJ
admet-34	181	51	microcrystal	microcrystal	ADJ
admet-34	181	52	drug	drug	NOUN
admet-34	181	53	,	,	PUNCT
admet-34	181	54	respectively	respectively	ADV
admet-34	181	55	)	)	PUNCT
admet-34	181	56	.	.	PUNCT
admet-34	182	1	in	in	ADP
admet-34	182	2	principle	principle	NOUN
admet-34	182	3	,	,	PUNCT
admet-34	182	4	the	the	DET
admet-34	182	5	model	model	NOUN
admet-34	182	6	could	could	AUX
admet-34	182	7	also	also	ADV
admet-34	182	8	account	account	VERB
admet-34	182	9	for	for	ADP
admet-34	182	10	the	the	DET
admet-34	182	11	ph	ph	ADJ
admet-34	182	12	dependence	dependence	NOUN
admet-34	182	13	of	of	ADP
admet-34	182	14	am	am	PROPN
admet-34	182	15	sc	sc	PROPN
admet-34	182	16	,	,	PUNCT
admet-34	182	17	nc	nc	PROPN
admet-34	182	18	sc	sc	PROPN
admet-34	182	19	,	,	PUNCT
admet-34	182	20	mc	mc	PROPN
admet-34	182	21	sc	sc	PROPN
admet-34	182	22	.	.	PUNCT
admet-34	183	1	this	this	PRON
admet-34	183	2	,	,	PUNCT
admet-34	183	3	of	of	ADP
admet-34	183	4	course	course	NOUN
admet-34	183	5	,	,	PUNCT
admet-34	183	6	would	would	AUX
admet-34	183	7	require	require	VERB
admet-34	183	8	the	the	DET
admet-34	183	9	definition	definition	NOUN
admet-34	183	10	of	of	ADP
admet-34	183	11	a	a	DET
admet-34	183	12	proper	proper	ADJ
admet-34	183	13	mathematical	mathematical	ADJ
admet-34	183	14	function	function	NOUN
admet-34	183	15	linking	link	VERB
admet-34	183	16	solubility	solubility	NOUN
admet-34	183	17	and	and	CCONJ
admet-34	183	18	ph	ph	NOUN
admet-34	183	19	.	.	PROPN
admet-34	183	20	as	as	SCONJ
admet-34	183	21	the	the	DET
admet-34	183	22	amorphous	amorphous	ADJ
admet-34	183	23	drug	drug	NOUN
admet-34	183	24	is	be	AUX
admet-34	183	25	often	often	ADV
admet-34	183	26	not	not	PART
admet-34	183	27	stable	stable	ADJ
admet-34	183	28	and	and	CCONJ
admet-34	183	29	,	,	PUNCT
admet-34	183	30	upon	upon	SCONJ
admet-34	183	31	dissolution	dissolution	NOUN
admet-34	183	32	,	,	PUNCT
admet-34	183	33	generally	generally	ADV
admet-34	183	34	transforms	transform	VERB
admet-34	183	35	into	into	ADP
admet-34	183	36	the	the	DET
admet-34	183	37	more	more	ADV
admet-34	183	38	thermodynamically	thermodynamically	ADV
admet-34	183	39	stable	stable	ADJ
admet-34	183	40	microcrystal	microcrystal	ADJ
admet-34	183	41	condition	condition	NOUN
admet-34	183	42	(	(	PUNCT
admet-34	183	43	re	re	NOUN
admet-34	183	44	-	-	NOUN
admet-34	183	45	crystallisation	crystallisation	NOUN
admet-34	183	46	;	;	PUNCT
admet-34	183	47	point	point	NOUN
admet-34	183	48	iv	iv	NUM
admet-34	183	49	)	)	PUNCT
admet-34	183	50	)	)	PUNCT
admet-34	183	51	,	,	PUNCT
admet-34	183	52	its	its	PRON
admet-34	183	53	solubility	solubility	NOUN
admet-34	183	54	reduces	reduce	VERB
admet-34	183	55	with	with	ADP
admet-34	183	56	time	time	NOUN
admet-34	183	57	according	accord	VERB
admet-34	183	58	to	to	ADP
admet-34	183	59	nogami	nogami	NOUN
admet-34	183	60	theory	theory	NOUN
admet-34	183	61	[	[	X
admet-34	183	62	20	20	NUM
admet-34	183	63	]	]	PUNCT
admet-34	183	64	(	(	PUNCT
admet-34	183	65	see	see	VERB
admet-34	183	66	eq	eq	ADP
admet-34	183	67	.	.	PUNCT
admet-34	184	1	(	(	PUNCT
admet-34	184	2	17	17	NUM
admet-34	184	3	)	)	PUNCT
admet-34	184	4	)	)	PUNCT
admet-34	184	5	where	where	SCONJ
admet-34	184	6	kr	kr	PROPN
admet-34	184	7	is	be	AUX
admet-34	184	8	the	the	DET
admet-34	184	9	recrystallisation	recrystallisation	NOUN
admet-34	184	10	constant	constant	ADJ
admet-34	184	11	and	and	CCONJ
admet-34	184	12	am	be	AUX
admet-34	184	13	s0c	s0c	NOUN
admet-34	184	14	is	be	AUX
admet-34	184	15	the	the	DET
admet-34	184	16	maximum	maximum	ADJ
admet-34	184	17	amorphous	amorphous	ADJ
admet-34	184	18	drug	drug	NOUN
admet-34	184	19	solubility	solubility	NOUN
admet-34	184	20	.	.	PUNCT
admet-34	185	1	obviously	obviously	ADV
admet-34	185	2	,	,	PUNCT
admet-34	185	3	drug	drug	NOUN
admet-34	185	4	recrystallization	recrystallization	NOUN
admet-34	185	5	can	can	AUX
admet-34	185	6	also	also	ADV
admet-34	185	7	take	take	VERB
admet-34	185	8	place	place	NOUN
admet-34	185	9	in	in	ADP
admet-34	185	10	the	the	DET
admet-34	185	11	release	release	NOUN
admet-34	185	12	environment	environment	NOUN
admet-34	185	13	and	and	CCONJ
admet-34	185	14	eq	eq	NOUN
admet-34	185	15	.	.	PUNCT
admet-34	186	1	(	(	PUNCT
admet-34	186	2	20	20	NUM
admet-34	186	3	)	)	PUNCT
admet-34	186	4	serves	serve	VERB
admet-34	186	5	to	to	PART
admet-34	186	6	account	account	VERB
admet-34	186	7	for	for	ADP
admet-34	186	8	this	this	DET
admet-34	186	9	phenomenon	phenomenon	NOUN
admet-34	186	10	.	.	PUNCT
admet-34	187	1	in	in	ADP
admet-34	187	2	particular	particular	ADJ
admet-34	187	3	,	,	PUNCT
admet-34	187	4	mc	mc	PROPN
admet-34	187	5	and	and	CCONJ
admet-34	187	6	krb	krb	PROPN
admet-34	187	7	are	be	AUX
admet-34	187	8	,	,	PUNCT
admet-34	187	9	respectively	respectively	ADV
admet-34	187	10	,	,	PUNCT
admet-34	187	11	the	the	DET
admet-34	187	12	amount	amount	NOUN
admet-34	187	13	of	of	ADP
admet-34	187	14	re	re	ADJ
admet-34	187	15	-	-	ADJ
admet-34	187	16	crystallized	crystallize	VERB
admet-34	187	17	drug	drug	NOUN
admet-34	187	18	up	up	ADP
admet-34	187	19	to	to	ADP
admet-34	187	20	time	time	NOUN
admet-34	187	21	t	t	PROPN
admet-34	187	22	and	and	CCONJ
admet-34	187	23	the	the	DET
admet-34	187	24	re	re	NOUN
admet-34	187	25	-	-	NOUN
admet-34	187	26	crystallization	crystallization	NOUN
admet-34	187	27	constant	constant	ADJ
admet-34	187	28	in	in	ADP
admet-34	187	29	the	the	DET
admet-34	187	30	release	release	NOUN
admet-34	187	31	environment	environment	NOUN
admet-34	187	32	.	.	PUNCT
admet-34	188	1	the	the	DET
admet-34	188	2	solution	solution	NOUN
admet-34	188	3	of	of	ADP
admet-34	188	4	eq	eq	PROPN
admet-34	188	5	.	.	PUNCT
admet-34	189	1	(	(	PUNCT
admet-34	189	2	14	14	NUM
admet-34	189	3	)	)	PUNCT
admet-34	189	4	is	be	AUX
admet-34	189	5	performed	perform	VERB
admet-34	189	6	by	by	ADP
admet-34	189	7	assuming	assume	VERB
admet-34	189	8	that	that	SCONJ
admet-34	189	9	,	,	PUNCT
admet-34	189	10	initially	initially	ADV
admet-34	189	11	,	,	PUNCT
admet-34	189	12	no	no	DET
admet-34	189	13	dissolved	dissolve	VERB
admet-34	189	14	drug	drug	NOUN
admet-34	189	15	exists	exist	VERB
admet-34	189	16	inside	inside	ADP
admet-34	189	17	the	the	DET
admet-34	189	18	particles	particle	NOUN
admet-34	189	19	(	(	PUNCT
admet-34	189	20	only	only	ADV
admet-34	189	21	solid	solid	ADJ
admet-34	189	22	or	or	CCONJ
admet-34	189	23	amorphous	amorphous	ADJ
admet-34	189	24	drug	drug	NOUN
admet-34	189	25	can	can	AUX
admet-34	189	26	be	be	AUX
admet-34	189	27	found	find	VERB
admet-34	189	28	in	in	ADP
admet-34	189	29	the	the	DET
admet-34	189	30	polymeric	polymeric	ADJ
admet-34	189	31	network	network	NOUN
admet-34	189	32	)	)	PUNCT
admet-34	189	33	and	and	CCONJ
admet-34	189	34	that	that	SCONJ
admet-34	189	35	the	the	DET
admet-34	189	36	solid	solid	ADJ
admet-34	189	37	and/or	and/or	CCONJ
admet-34	189	38	amorphous	amorphous	ADJ
admet-34	189	39	drug	drug	NOUN
admet-34	189	40	concentration	concentration	NOUN
admet-34	189	41	are	be	AUX
admet-34	189	42	uniform	uniform	ADJ
admet-34	189	43	inside	inside	ADP
admet-34	189	44	the	the	DET
admet-34	189	45	particles	particle	NOUN
admet-34	189	46	(	(	PUNCT
admet-34	189	47	the	the	DET
admet-34	189	48	model	model	NOUN
admet-34	189	49	could	could	AUX
admet-34	189	50	easily	easily	ADV
admet-34	189	51	account	account	VERB
admet-34	189	52	for	for	ADP
admet-34	189	53	more	more	ADJ
admet-34	189	54	complex	complex	ADJ
admet-34	189	55	drug	drug	NOUN
admet-34	189	56	distributions	distribution	NOUN
admet-34	189	57	)	)	PUNCT
admet-34	189	58	.	.	PUNCT
admet-34	190	1	finally	finally	ADV
admet-34	190	2	,	,	PUNCT
admet-34	190	3	for	for	ADP
admet-34	190	4	admet	admet	PROPN
admet-34	190	5	&	&	CCONJ
admet-34	190	6	dmpk	dmpk	PROPN
admet-34	190	7	2(2	2(2	NUM
admet-34	190	8	)	)	PUNCT
admet-34	190	9	(	(	PUNCT
admet-34	190	10	2014	2014	NUM
admet-34	190	11	)	)	PUNCT
admet-34	190	12	80	80	NUM
admet-34	190	13	-	-	SYM
admet-34	190	14	97	97	NUM
admet-34	190	15	in	in	ADP
admet-34	190	16	vivo	vivo	ADJ
admet-34	190	17	drug	drug	NOUN
admet-34	190	18	release	release	NOUN
admet-34	190	19	and	and	CCONJ
admet-34	190	20	absorption	absorption	NOUN
admet-34	190	21	doi	doi	NOUN
admet-34	190	22	:	:	PUNCT
admet-34	190	23	10.5599	10.5599	NUM
admet-34	190	24	/	/	SYM
admet-34	190	25	admet.2.2.34	admet.2.2.34	ADJ
admet-34	190	26	87	87	NUM
admet-34	190	27	symmetry	symmetry	NOUN
admet-34	190	28	reasons	reason	NOUN
admet-34	190	29	,	,	PUNCT
admet-34	190	30	drug	drug	NOUN
admet-34	190	31	flux	flux	NOUN
admet-34	190	32	in	in	ADP
admet-34	190	33	the	the	DET
admet-34	190	34	particle	particle	NOUN
admet-34	190	35	center	center	NOUN
admet-34	190	36	is	be	AUX
admet-34	190	37	set	set	VERB
admet-34	190	38	to	to	ADP
admet-34	190	39	zero	zero	NUM
admet-34	190	40	and	and	CCONJ
admet-34	190	41	the	the	DET
admet-34	190	42	usual	usual	ADJ
admet-34	190	43	drug	drug	NOUN
admet-34	190	44	partitioning	partition	VERB
admet-34	190	45	condition	condition	NOUN
admet-34	190	46	at	at	ADP
admet-34	190	47	the	the	DET
admet-34	190	48	particle	particle	NOUN
admet-34	190	49	/	/	SYM
admet-34	190	50	solvent	solvent	NOUN
admet-34	190	51	interface	interface	NOUN
admet-34	190	52	is	be	AUX
admet-34	190	53	considered	consider	VERB
admet-34	190	54	(	(	PUNCT
admet-34	190	55	kp	kp	PROPN
admet-34	190	56	is	be	AUX
admet-34	190	57	the	the	DET
admet-34	190	58	drug	drug	NOUN
admet-34	190	59	partition	partition	NOUN
admet-34	190	60	coefficient	coefficient	NOUN
admet-34	190	61	)	)	PUNCT
admet-34	190	62	.	.	PUNCT
admet-34	191	1	in	in	ADP
admet-34	191	2	order	order	NOUN
admet-34	191	3	to	to	PART
admet-34	191	4	deal	deal	VERB
admet-34	191	5	with	with	ADP
admet-34	191	6	the	the	DET
admet-34	191	7	balance	balance	NOUN
admet-34	191	8	between	between	ADP
admet-34	191	9	problem	problem	NOUN
admet-34	191	10	unknowns	unknown	NOUN
admet-34	191	11	(	(	PUNCT
admet-34	191	12	cgics	cgic	NOUN
admet-34	191	13	,	,	PUNCT
admet-34	191	14	cl	cl	NOUN
admet-34	191	15	,	,	PUNCT
admet-34	191	16	cp	cp	PROPN
admet-34	191	17	,	,	PUNCT
admet-34	191	18	ct	ct	PROPN
admet-34	191	19	,	,	PUNCT
admet-34	191	20	cpi	cpi	PROPN
admet-34	191	21	,	,	PUNCT
admet-34	191	22	ci	ci	PROPN
admet-34	191	23	,	,	PUNCT
admet-34	191	24	cr	cr	PRON
admet-34	191	25	)	)	PUNCT
admet-34	191	26	and	and	CCONJ
admet-34	191	27	equations	equation	NOUN
admet-34	191	28	,	,	PUNCT
admet-34	191	29	it	it	PRON
admet-34	191	30	is	be	AUX
admet-34	191	31	necessary	necessary	ADJ
admet-34	191	32	to	to	PART
admet-34	191	33	add	add	VERB
admet-34	191	34	a	a	DET
admet-34	191	35	further	further	ADJ
admet-34	191	36	equation	equation	NOUN
admet-34	191	37	for	for	ADP
admet-34	191	38	the	the	DET
admet-34	191	39	definition	definition	NOUN
admet-34	191	40	of	of	ADP
admet-34	191	41	cr	cr	PROPN
admet-34	191	42	.	.	PUNCT
admet-34	192	1	in	in	ADP
admet-34	192	2	particular	particular	ADJ
admet-34	192	3	,	,	PUNCT
admet-34	192	4	the	the	DET
admet-34	192	5	overall	overall	ADJ
admet-34	192	6	drug	drug	NOUN
admet-34	192	7	mass	mass	NOUN
admet-34	192	8	balance	balance	NOUN
admet-34	192	9	made	make	VERB
admet-34	192	10	on	on	ADP
admet-34	192	11	drug	drug	NOUN
admet-34	192	12	is	be	AUX
admet-34	192	13	considered	consider	VERB
admet-34	192	14	:	:	PUNCT
admet-34	192	15			NOUN
admet-34	192	16			SYM
admet-34	192	17			NOUN
admet-34	192	18			SYM
admet-34	192	19			NOUN
admet-34	192	20			SYM
admet-34	192	21			NOUN
admet-34	192	22			PROPN
admet-34	192	23	pic	pic	NOUN
admet-34	192	24	am	be	AUX
admet-34	192	25	nc	nc	PROPN
admet-34	192	26	mc	mc	PROPN
admet-34	192	27	2	2	NUM
admet-34	192	28	0	0	NUM
admet-34	193	1	r	r	NOUN
admet-34	193	2	r	r	NOUN
admet-34	194	1	pi	pi	NOUN
admet-34	195	1	i	i	PRON
admet-34	196	1	i	i	PRON
admet-34	196	2	di	di	VERB
admet-34	197	1	i	i	PRON
admet-34	197	2	di	di	VERB
admet-34	198	1	i	i	PRON
admet-34	198	2	di	di	VERB
admet-34	199	1	i	i	PRON
admet-34	199	2	i	i	PRON
admet-34	200	1	i	i	PRON
admet-34	200	2	gics	gic	VERB
admet-34	200	3	gics	gic	NOUN
admet-34	200	4	l	l	NOUN
admet-34	200	5	l	l	NOUN
admet-34	201	1	p	p	X
admet-34	201	2	p	p	X
admet-34	201	3	t	t	X
admet-34	201	4	t	t	NOUN
admet-34	201	5	c	c	PROPN
admet-34	202	1	el	el	PROPN
admet-34	202	2	i	i	PROPN
admet-34	202	3	1	1	NUM
admet-34	202	4	0	0	NUM
admet-34	202	5	4π	4π	NUM
admet-34	202	6	d	d	PROPN
admet-34	202	7	rn	rn	PROPN
admet-34	202	8	m	m	PROPN
admet-34	202	9	v	v	PROPN
admet-34	202	10	c	c	PROPN
admet-34	202	11	n	n	NOUN
admet-34	202	12	c	c	NOUN
admet-34	202	13	r	r	NOUN
admet-34	202	14	c	c	NOUN
admet-34	202	15	r	r	NOUN
admet-34	202	16	c	c	NOUN
admet-34	202	17	r	r	NOUN
admet-34	202	18	c	c	NOUN
admet-34	202	19	r	r	NOUN
admet-34	202	20	r	r	NOUN
admet-34	202	21	r	r	NOUN
admet-34	202	22	v	v	NOUN
admet-34	202	23	c	c	NOUN
admet-34	202	24	v	v	NOUN
admet-34	202	25	c	c	NOUN
admet-34	202	26	v	v	NOUN
admet-34	202	27	c	c	NOUN
admet-34	202	28	v	v	NOUN
admet-34	202	29	c	c	NOUN
admet-34	202	30	m	m	VERB
admet-34	202	31	m	m	VERB
admet-34	202	32			ADJ
admet-34	202	33			PROPN
admet-34	202	34			ADV
admet-34	202	35			PUNCT
admet-34	202	36			PROPN
admet-34	202	37			PROPN
admet-34	202	38			PROPN
admet-34	202	39			PROPN
admet-34	202	40			PROPN
admet-34	202	41			PUNCT
admet-34	202	42			PUNCT
admet-34	202	43			ADV
admet-34	202	44			X
admet-34	202	45			X
admet-34	202	46			X
admet-34	202	47			PUNCT
admet-34	202	48	(	(	PUNCT
admet-34	202	49	21	21	NUM
admet-34	202	50	)	)	PUNCT
admet-34	202	51	where	where	SCONJ
admet-34	202	52	m0	m0	NOUN
admet-34	202	53	is	be	AUX
admet-34	202	54	the	the	DET
admet-34	202	55	administered	administer	VERB
admet-34	202	56	drug	drug	NOUN
admet-34	202	57	dose	dose	PROPN
admet-34	202	58	,	,	PUNCT
admet-34	202	59	nc	nc	PROPN
admet-34	202	60	is	be	AUX
admet-34	202	61	the	the	DET
admet-34	202	62	number	number	NOUN
admet-34	202	63	of	of	ADP
admet-34	202	64	classes	class	NOUN
admet-34	202	65	into	into	ADP
admet-34	202	66	which	which	PRON
admet-34	202	67	the	the	DET
admet-34	202	68	continuous	continuous	ADJ
admet-34	202	69	particle	particle	NOUN
admet-34	202	70	size	size	NOUN
admet-34	202	71	distribution	distribution	NOUN
admet-34	202	72	has	have	AUX
admet-34	202	73	been	be	AUX
admet-34	202	74	subdivided	subdivide	VERB
admet-34	202	75	into	into	ADP
admet-34	202	76	(	(	PUNCT
admet-34	202	77	eq	eq	NOUN
admet-34	202	78	.	.	PUNCT
admet-34	203	1	(	(	PUNCT
admet-34	203	2	9	9	NUM
admet-34	203	3	)	)	PUNCT
admet-34	203	4	)	)	PUNCT
admet-34	204	1	and	and	CCONJ
admet-34	204	2	npi	npi	PROPN
admet-34	204	3	is	be	AUX
admet-34	204	4	the	the	DET
admet-34	204	5	number	number	NOUN
admet-34	204	6	of	of	ADP
admet-34	204	7	particles	particle	NOUN
admet-34	204	8	belonging	belong	VERB
admet-34	204	9	to	to	ADP
admet-34	204	10	the	the	DET
admet-34	204	11	“	"	PUNCT
admet-34	204	12	ith	ith	PROPN
admet-34	204	13	”	"	PUNCT
admet-34	204	14	class	class	NOUN
admet-34	204	15	(	(	PUNCT
admet-34	204	16	npi	npi	PROPN
admet-34	204	17	can	can	AUX
admet-34	204	18	be	be	AUX
admet-34	204	19	simply	simply	ADV
admet-34	204	20	evaluated	evaluate	VERB
admet-34	204	21	on	on	ADP
admet-34	204	22	the	the	DET
admet-34	204	23	basis	basis	NOUN
admet-34	204	24	of	of	ADP
admet-34	204	25	eq	eq	PROPN
admet-34	204	26	.	.	PUNCT
admet-34	205	1	(	(	PUNCT
admet-34	205	2	9	9	NUM
admet-34	205	3	)	)	PUNCT
admet-34	205	4	)	)	PUNCT
admet-34	205	5	.	.	PUNCT
admet-34	206	1	eq	eq	X
admet-34	206	2	.	.	PUNCT
admet-34	207	1	(	(	PUNCT
admet-34	207	2	21	21	NUM
admet-34	207	3	)	)	PUNCT
admet-34	207	4	simply	simply	ADV
admet-34	207	5	states	state	VERB
admet-34	207	6	that	that	SCONJ
admet-34	207	7	,	,	PUNCT
admet-34	207	8	at	at	ADP
admet-34	207	9	anytime	anytime	NOUN
admet-34	207	10	,	,	PUNCT
admet-34	207	11	the	the	DET
admet-34	207	12	summed	sum	VERB
admet-34	207	13	drug	drug	NOUN
admet-34	207	14	amount	amount	NOUN
admet-34	207	15	in	in	ADP
admet-34	207	16	the	the	DET
admet-34	207	17	release	release	NOUN
admet-34	207	18	environment	environment	NOUN
admet-34	207	19	(	(	PUNCT
admet-34	207	20	first	first	ADJ
admet-34	207	21	addendum	addendum	NOUN
admet-34	207	22	in	in	ADP
admet-34	207	23	eq	eq	ADP
admet-34	207	24	.	.	PUNCT
admet-34	208	1	(	(	PUNCT
admet-34	208	2	21	21	NUM
admet-34	208	3	)	)	PUNCT
admet-34	208	4	right	right	ADJ
admet-34	208	5	hand	hand	NOUN
admet-34	208	6	side	side	NOUN
admet-34	208	7	)	)	PUNCT
admet-34	208	8	,	,	PUNCT
admet-34	208	9	in	in	ADP
admet-34	208	10	the	the	DET
admet-34	208	11	particles	particle	NOUN
admet-34	208	12	(	(	PUNCT
admet-34	208	13	sum	sum	NOUN
admet-34	208	14	of	of	ADP
admet-34	208	15	integrals	integral	NOUN
admet-34	208	16	in	in	ADP
admet-34	208	17	eq	eq	ADP
admet-34	208	18	.	.	PUNCT
admet-34	209	1	(	(	PUNCT
admet-34	209	2	21	21	NUM
admet-34	209	3	)	)	PUNCT
admet-34	209	4	right	right	ADJ
admet-34	209	5	hand	hand	NOUN
admet-34	209	6	side	side	NOUN
admet-34	209	7	)	)	PUNCT
admet-34	209	8	,	,	PUNCT
admet-34	209	9	in	in	ADP
admet-34	209	10	the	the	DET
admet-34	209	11	gics	gic	NOUN
admet-34	209	12	(	(	PUNCT
admet-34	209	13	third	third	ADJ
admet-34	209	14	addendum	addendum	NOUN
admet-34	209	15	in	in	ADP
admet-34	209	16	eq	eq	PROPN
admet-34	209	17	.	.	PUNCT
admet-34	210	1	(	(	PUNCT
admet-34	210	2	21	21	NUM
admet-34	210	3	)	)	PUNCT
admet-34	210	4	right	right	ADJ
admet-34	210	5	hand	hand	NOUN
admet-34	210	6	side	side	NOUN
admet-34	210	7	)	)	PUNCT
admet-34	210	8	,	,	PUNCT
admet-34	210	9	in	in	ADP
admet-34	210	10	the	the	DET
admet-34	210	11	liver	liver	NOUN
admet-34	210	12	(	(	PUNCT
admet-34	210	13	fourth	fourth	ADJ
admet-34	210	14	addendum	addendum	NOUN
admet-34	210	15	in	in	ADP
admet-34	210	16	eq	eq	PROPN
admet-34	210	17	.	.	PUNCT
admet-34	211	1	(	(	PUNCT
admet-34	211	2	21	21	NUM
admet-34	211	3	)	)	PUNCT
admet-34	211	4	right	right	ADJ
admet-34	211	5	hand	hand	NOUN
admet-34	211	6	side	side	NOUN
admet-34	211	7	)	)	PUNCT
admet-34	211	8	,	,	PUNCT
admet-34	211	9	in	in	ADP
admet-34	211	10	plasma	plasma	NOUN
admet-34	211	11	(	(	PUNCT
admet-34	211	12	fifth	fifth	ADJ
admet-34	211	13	addendum	addendum	NOUN
admet-34	211	14	in	in	ADP
admet-34	211	15	eq	eq	PROPN
admet-34	211	16	.	.	PUNCT
admet-34	212	1	(	(	PUNCT
admet-34	212	2	21	21	NUM
admet-34	212	3	)	)	PUNCT
admet-34	212	4	right	right	ADJ
admet-34	212	5	hand	hand	NOUN
admet-34	212	6	side	side	NOUN
admet-34	212	7	)	)	PUNCT
admet-34	212	8	,	,	PUNCT
admet-34	212	9	inside	inside	ADP
admet-34	212	10	tissues	tissue	NOUN
admet-34	212	11	(	(	PUNCT
admet-34	212	12	sixth	sixth	ADJ
admet-34	212	13	addendum	addendum	NOUN
admet-34	212	14	in	in	ADP
admet-34	212	15	eq	eq	PROPN
admet-34	212	16	.	.	PUNCT
admet-34	213	1	(	(	PUNCT
admet-34	213	2	21	21	NUM
admet-34	213	3	)	)	PUNCT
admet-34	213	4	right	right	ADJ
admet-34	213	5	hand	hand	NOUN
admet-34	213	6	side	side	NOUN
admet-34	213	7	)	)	PUNCT
admet-34	213	8	plus	plus	CCONJ
admet-34	213	9	the	the	DET
admet-34	213	10	drug	drug	NOUN
admet-34	213	11	amount	amount	NOUN
admet-34	213	12	recrystallized	recrystallize	VERB
admet-34	213	13	(	(	PUNCT
admet-34	213	14	mc	mc	NOUN
admet-34	213	15	)	)	PUNCT
admet-34	213	16	and	and	CCONJ
admet-34	213	17	eliminated	eliminate	VERB
admet-34	213	18	(	(	PUNCT
admet-34	213	19	mel	mel	PROPN
admet-34	213	20	)	)	PUNCT
admet-34	213	21	must	must	AUX
admet-34	213	22	be	be	AUX
admet-34	213	23	equal	equal	ADJ
admet-34	213	24	to	to	ADP
admet-34	213	25	the	the	DET
admet-34	213	26	administered	administer	VERB
admet-34	213	27	dose	dose	NOUN
admet-34	213	28	m0	m0	PROPN
admet-34	213	29	.	.	PUNCT
admet-34	214	1	interestingly	interestingly	ADV
admet-34	214	2	,	,	PUNCT
admet-34	214	3	the	the	DET
admet-34	214	4	use	use	NOUN
admet-34	214	5	of	of	ADP
admet-34	214	6	eq	eq	PROPN
admet-34	214	7	.	.	PUNCT
admet-34	215	1	(	(	PUNCT
admet-34	215	2	21	21	NUM
admet-34	215	3	)	)	PUNCT
admet-34	215	4	is	be	AUX
admet-34	215	5	allowed	allow	VERB
admet-34	215	6	only	only	ADV
admet-34	215	7	if	if	SCONJ
admet-34	215	8	the	the	DET
admet-34	215	9	other	other	ADJ
admet-34	215	10	model	model	NOUN
admet-34	215	11	kinetic	kinetic	NOUN
admet-34	215	12	equations	equation	NOUN
admet-34	215	13	(	(	PUNCT
admet-34	215	14	2	2	NUM
admet-34	215	15	-	-	SYM
admet-34	215	16	5	5	NUM
admet-34	215	17	)	)	PUNCT
admet-34	215	18	are	be	AUX
admet-34	215	19	expression	expression	NOUN
admet-34	215	20	of	of	ADP
admet-34	215	21	drug	drug	NOUN
admet-34	215	22	mass	mass	NOUN
admet-34	215	23	balance	balance	NOUN
admet-34	215	24	in	in	ADP
admet-34	215	25	the	the	DET
admet-34	215	26	different	different	ADJ
admet-34	215	27	body	body	NOUN
admet-34	215	28	compartments	compartment	NOUN
admet-34	215	29	considered	consider	VERB
admet-34	215	30	(	(	PUNCT
admet-34	215	31	gics	gic	NOUN
admet-34	215	32	,	,	PUNCT
admet-34	215	33	liver	liver	NOUN
admet-34	215	34	,	,	PUNCT
admet-34	215	35	plasma	plasma	NOUN
admet-34	215	36	and	and	CCONJ
admet-34	215	37	tissues	tissue	NOUN
admet-34	215	38	)	)	PUNCT
admet-34	215	39	.	.	PUNCT
admet-34	216	1	due	due	ADP
admet-34	216	2	to	to	ADP
admet-34	216	3	the	the	DET
admet-34	216	4	simultaneous	simultaneous	ADJ
admet-34	216	5	presence	presence	NOUN
admet-34	216	6	of	of	ADP
admet-34	216	7	ordinary	ordinary	ADJ
admet-34	216	8	and	and	CCONJ
admet-34	216	9	partial	partial	ADJ
admet-34	216	10	differential	differential	NOUN
admet-34	216	11	equations	equation	NOUN
admet-34	216	12	,	,	PUNCT
admet-34	216	13	the	the	DET
admet-34	216	14	solution	solution	NOUN
admet-34	216	15	of	of	ADP
admet-34	216	16	the	the	DET
admet-34	216	17	model	model	NOUN
admet-34	216	18	calls	call	VERB
admet-34	216	19	for	for	ADP
admet-34	216	20	a	a	DET
admet-34	216	21	numerical	numerical	ADJ
admet-34	216	22	algorithm	algorithm	NOUN
admet-34	216	23	.	.	PUNCT
admet-34	217	1	in	in	ADP
admet-34	217	2	particular	particular	ADJ
admet-34	217	3	,	,	PUNCT
admet-34	217	4	the	the	DET
admet-34	217	5	ordinary	ordinary	ADJ
admet-34	217	6	differential	differential	ADJ
admet-34	217	7	equations	equation	NOUN
admet-34	217	8	have	have	AUX
admet-34	217	9	been	be	AUX
admet-34	217	10	converted	convert	VERB
admet-34	217	11	into	into	ADP
admet-34	217	12	linear	linear	ADJ
admet-34	217	13	algebraic	algebraic	ADJ
admet-34	217	14	equations	equation	NOUN
admet-34	217	15	according	accord	VERB
admet-34	217	16	to	to	ADP
admet-34	217	17	the	the	DET
admet-34	217	18	implicit	implicit	ADJ
admet-34	217	19	euler	euler	NOUN
admet-34	217	20	method	method	NOUN
admet-34	217	21	[	[	X
admet-34	217	22	21	21	NUM
admet-34	217	23	]	]	PUNCT
admet-34	217	24	while	while	SCONJ
admet-34	217	25	the	the	DET
admet-34	217	26	implicit	implicit	ADJ
admet-34	217	27	control	control	NOUN
admet-34	217	28	volume	volume	NOUN
admet-34	217	29	[	[	X
admet-34	217	30	22	22	NUM
admet-34	217	31	]	]	PUNCT
admet-34	217	32	(	(	PUNCT
admet-34	217	33	10	10	NUM
admet-34	217	34	particles	particle	NOUN
admet-34	217	35	classes	class	NOUN
admet-34	217	36	,	,	PUNCT
admet-34	217	37	15	15	NUM
admet-34	217	38	radial	radial	ADJ
admet-34	217	39	subdivisions	subdivision	NOUN
admet-34	217	40	)	)	PUNCT
admet-34	217	41	has	have	AUX
admet-34	217	42	been	be	AUX
admet-34	217	43	considered	consider	VERB
admet-34	217	44	for	for	ADP
admet-34	217	45	the	the	DET
admet-34	217	46	partial	partial	ADJ
admet-34	217	47	differential	differential	NOUN
admet-34	217	48	equations	equation	NOUN
admet-34	217	49	conversion	conversion	NOUN
admet-34	217	50	into	into	ADP
admet-34	217	51	linear	linear	PROPN
admet-34	217	52	and	and	CCONJ
admet-34	217	53	non	non	ADJ
admet-34	217	54	linear	linear	ADJ
admet-34	217	55	algebraic	algebraic	ADJ
admet-34	217	56	equations	equation	NOUN
admet-34	217	57	.	.	PUNCT
admet-34	218	1	in	in	ADP
admet-34	218	2	order	order	NOUN
admet-34	218	3	to	to	PART
admet-34	218	4	ensure	ensure	VERB
admet-34	218	5	numerical	numerical	ADJ
admet-34	218	6	solution	solution	NOUN
admet-34	218	7	accuracy	accuracy	NOUN
admet-34	218	8	,	,	PUNCT
admet-34	218	9	the	the	DET
admet-34	218	10	integration	integration	NOUN
admet-34	218	11	time	time	NOUN
admet-34	218	12	step	step	NOUN
admet-34	218	13	was	be	AUX
admet-34	218	14	set	set	VERB
admet-34	218	15	to	to	ADP
admet-34	218	16	1	1	NUM
admet-34	218	17	s.	s.	NOUN
admet-34	218	18	the	the	DET
admet-34	218	19	relaxation	relaxation	NOUN
admet-34	218	20	method	method	NOUN
admet-34	218	21	[	[	X
admet-34	218	22	21	21	NUM
admet-34	218	23	]	]	PUNCT
admet-34	218	24	has	have	AUX
admet-34	218	25	been	be	AUX
admet-34	218	26	used	use	VERB
admet-34	218	27	for	for	ADP
admet-34	218	28	the	the	DET
admet-34	218	29	iterative	iterative	NOUN
admet-34	218	30	solution	solution	NOUN
admet-34	218	31	of	of	ADP
admet-34	218	32	our	our	PRON
admet-34	218	33	algebraic	algebraic	ADJ
admet-34	218	34	equations	equation	NOUN
admet-34	218	35	system	system	NOUN
admet-34	218	36	.	.	PUNCT
admet-34	219	1	the	the	DET
admet-34	219	2	solution	solution	NOUN
admet-34	219	3	of	of	ADP
admet-34	219	4	each	each	DET
admet-34	219	5	iteration	iteration	NOUN
admet-34	219	6	was	be	AUX
admet-34	219	7	carried	carry	VERB
admet-34	219	8	out	out	ADP
admet-34	219	9	according	accord	VERB
admet-34	219	10	to	to	ADP
admet-34	219	11	the	the	DET
admet-34	219	12	lu	lu	NOUN
admet-34	219	13	decomposition	decomposition	NOUN
admet-34	219	14	approach	approach	NOUN
admet-34	219	15	[	[	X
admet-34	219	16	21	21	NUM
admet-34	219	17	]	]	PUNCT
admet-34	219	18	.	.	PUNCT
admet-34	220	1	a	a	DET
admet-34	220	2	home	home	NOUN
admet-34	220	3	-	-	PUNCT
admet-34	220	4	made	make	VERB
admet-34	220	5	fortran	fortran	ADJ
admet-34	220	6	code	code	NOUN
admet-34	220	7	was	be	AUX
admet-34	220	8	built	build	VERB
admet-34	220	9	up	up	ADP
admet-34	220	10	for	for	ADP
admet-34	220	11	the	the	DET
admet-34	220	12	numerical	numerical	ADJ
admet-34	220	13	solution	solution	NOUN
admet-34	220	14	.	.	PUNCT
admet-34	221	1	results	result	NOUN
admet-34	221	2	and	and	CCONJ
admet-34	221	3	discussion	discussion	NOUN
admet-34	221	4	one	one	NUM
admet-34	221	5	of	of	ADP
admet-34	221	6	the	the	DET
admet-34	221	7	critical	critical	ADJ
admet-34	221	8	factors	factor	NOUN
admet-34	221	9	connected	connect	VERB
admet-34	221	10	to	to	ADP
admet-34	221	11	the	the	DET
admet-34	221	12	use	use	NOUN
admet-34	221	13	of	of	ADP
admet-34	221	14	pbpk	pbpk	NOUN
admet-34	221	15	models	model	NOUN
admet-34	221	16	is	be	AUX
admet-34	221	17	the	the	DET
admet-34	221	18	availability	availability	NOUN
admet-34	221	19	of	of	ADP
admet-34	221	20	reliable	reliable	ADJ
admet-34	221	21	values	value	NOUN
admet-34	221	22	for	for	ADP
admet-34	221	23	the	the	DET
admet-34	221	24	model	model	NOUN
admet-34	221	25	parameters	parameter	NOUN
admet-34	221	26	.	.	PUNCT
admet-34	222	1	of	of	ADP
admet-34	222	2	course	course	ADV
admet-34	222	3	,	,	PUNCT
admet-34	222	4	this	this	PRON
admet-34	222	5	is	be	AUX
admet-34	222	6	not	not	PART
admet-34	222	7	a	a	DET
admet-34	222	8	trivial	trivial	ADJ
admet-34	222	9	problem	problem	NOUN
admet-34	222	10	[	[	X
admet-34	222	11	1	1	NUM
admet-34	222	12	-	-	SYM
admet-34	222	13	5	5	NUM
admet-34	222	14	]	]	PUNCT
admet-34	222	15	because	because	SCONJ
admet-34	222	16	different	different	ADJ
admet-34	222	17	values	value	NOUN
admet-34	222	18	for	for	ADP
admet-34	222	19	the	the	DET
admet-34	222	20	same	same	ADJ
admet-34	222	21	parameter	parameter	NOUN
admet-34	222	22	can	can	AUX
admet-34	222	23	be	be	AUX
admet-34	222	24	found	find	VERB
admet-34	222	25	in	in	ADP
admet-34	222	26	the	the	DET
admet-34	222	27	literature	literature	NOUN
admet-34	222	28	due	due	ADJ
admet-34	222	29	,	,	PUNCT
admet-34	222	30	in	in	ADP
admet-34	222	31	some	some	DET
admet-34	222	32	cases	case	NOUN
admet-34	222	33	to	to	ADP
admet-34	222	34	considerable	considerable	ADJ
admet-34	222	35	inter	inter	ADJ
admet-34	222	36	-	-	ADJ
admet-34	222	37	subjects	subject	NOUN
admet-34	222	38	variability	variability	NOUN
admet-34	222	39	[	[	X
admet-34	222	40	23	23	NUM
admet-34	222	41	–	–	PUNCT
admet-34	222	42	29	29	NUM
admet-34	222	43	]	]	PUNCT
admet-34	222	44	.	.	PUNCT
admet-34	223	1	accordingly	accordingly	ADV
admet-34	223	2	,	,	PUNCT
admet-34	223	3	in	in	ADP
admet-34	223	4	order	order	NOUN
admet-34	223	5	to	to	PART
admet-34	223	6	simplify	simplify	VERB
admet-34	223	7	comparison	comparison	NOUN
admet-34	223	8	of	of	ADP
admet-34	223	9	the	the	DET
admet-34	223	10	three	three	NUM
admet-34	223	11	different	different	ADJ
admet-34	223	12	drugs	drug	NOUN
admet-34	223	13	considered	consider	VERB
admet-34	223	14	in	in	ADP
admet-34	223	15	this	this	DET
admet-34	223	16	paper	paper	NOUN
admet-34	223	17	(	(	PUNCT
admet-34	223	18	theophylline	theophylline	NOUN
admet-34	223	19	,	,	PUNCT
admet-34	223	20	temazepam	temazepam	NOUN
admet-34	223	21	and	and	CCONJ
admet-34	223	22	nimesulide	nimesulide	NOUN
admet-34	223	23	)	)	PUNCT
admet-34	223	24	,	,	PUNCT
admet-34	223	25	we	we	PRON
admet-34	223	26	decided	decide	VERB
admet-34	223	27	to	to	PART
admet-34	223	28	rely	rely	VERB
admet-34	223	29	exclusively	exclusively	ADV
admet-34	223	30	on	on	ADP
admet-34	223	31	the	the	DET
admet-34	223	32	information	information	NOUN
admet-34	223	33	reported	report	VERB
admet-34	223	34	in	in	ADP
admet-34	223	35	[	[	X
admet-34	223	36	10	10	NUM
admet-34	223	37	]	]	PUNCT
admet-34	223	38	as	as	ADP
admet-34	223	39	source	source	NOUN
admet-34	223	40	of	of	ADP
admet-34	223	41	pk	pk	NOUN
admet-34	223	42	parameters	parameter	NOUN
admet-34	223	43	values	value	NOUN
admet-34	223	44	.	.	PUNCT
admet-34	224	1	the	the	DET
admet-34	224	2	first	first	ADJ
admet-34	224	3	drug	drug	NOUN
admet-34	224	4	considered	consider	VERB
admet-34	224	5	,	,	PUNCT
admet-34	224	6	theophylline	theophylline	NOUN
admet-34	224	7	,	,	PUNCT
admet-34	224	8	also	also	ADV
admet-34	224	9	known	know	VERB
admet-34	224	10	as	as	ADP
admet-34	224	11	1,3	1,3	NUM
admet-34	224	12	-	-	PUNCT
admet-34	224	13	dimethylxanthine	dimethylxanthine	NOUN
admet-34	224	14	,	,	PUNCT
admet-34	224	15	is	be	AUX
admet-34	224	16	a	a	DET
admet-34	224	17	methylxanthine	methylxanthine	ADJ
admet-34	224	18	drug	drug	NOUN
admet-34	224	19	that	that	PRON
admet-34	224	20	finds	find	VERB
admet-34	224	21	a	a	DET
admet-34	224	22	wide	wide	ADJ
admet-34	224	23	clinical	clinical	ADJ
admet-34	224	24	use	use	NOUN
admet-34	224	25	in	in	ADP
admet-34	224	26	the	the	DET
admet-34	224	27	treatment	treatment	NOUN
admet-34	224	28	of	of	ADP
admet-34	224	29	respiratory	respiratory	ADJ
admet-34	224	30	diseases	disease	NOUN
admet-34	224	31	such	such	ADJ
admet-34	224	32	as	as	ADP
admet-34	224	33	asthma	asthma	NOUN
admet-34	224	34	.	.	PUNCT
admet-34	225	1	its	its	PRON
admet-34	225	2	chemical	chemical	NOUN
admet-34	225	3	/	/	SYM
admet-34	225	4	physical	physical	ADJ
admet-34	225	5	and	and	CCONJ
admet-34	225	6	pk	pk	NOUN
admet-34	225	7	characteristics	characteristic	NOUN
admet-34	225	8	are	be	AUX
admet-34	225	9	reported	report	VERB
admet-34	225	10	in	in	ADP
admet-34	225	11	table	table	NOUN
admet-34	225	12	1	1	NUM
admet-34	225	13	.	.	PUNCT
admet-34	225	14	figure	figure	NOUN
admet-34	225	15	2a	2a	PROPN
admet-34	225	16	shows	show	VERB
admet-34	225	17	the	the	DET
admet-34	225	18	results	result	NOUN
admet-34	225	19	of	of	ADP
admet-34	225	20	model	model	NOUN
admet-34	225	21	simulations	simulation	NOUN
admet-34	225	22	when	when	SCONJ
admet-34	225	23	assuming	assume	VERB
admet-34	225	24	an	an	DET
admet-34	225	25	orally	orally	ADV
admet-34	225	26	administered	administer	VERB
admet-34	225	27	dose	dose	NOUN
admet-34	225	28	of	of	ADP
admet-34	225	29	100	100	NUM
admet-34	225	30	mg	mg	NOUN
admet-34	225	31	dispersed	disperse	VERB
admet-34	225	32	in	in	ADP
admet-34	225	33	a	a	DET
admet-34	225	34	polymeric	polymeric	ADJ
admet-34	225	35	carrier	carrier	NOUN
admet-34	225	36	with	with	ADP
admet-34	225	37	a	a	DET
admet-34	225	38	volume	volume	NOUN
admet-34	225	39	of	of	ADP
admet-34	225	40	1	1	NUM
admet-34	225	41	cm3	cm3	NOUN
admet-34	225	42	.	.	PUNCT
admet-34	226	1	in	in	ADP
admet-34	226	2	particular	particular	ADJ
admet-34	226	3	,	,	PUNCT
admet-34	226	4	the	the	DET
admet-34	226	5	continuous	continuous	ADJ
admet-34	226	6	thick	thick	ADJ
admet-34	226	7	solid	solid	ADJ
admet-34	226	8	line	line	NOUN
admet-34	226	9	refers	refer	VERB
admet-34	226	10	to	to	ADP
admet-34	226	11	theophylline	theophylline	ADJ
admet-34	226	12	concentration	concentration	NOUN
admet-34	226	13	in	in	ADP
admet-34	226	14	the	the	DET
admet-34	226	15	plasma	plasma	NOUN
admet-34	226	16	(	(	PUNCT
admet-34	226	17	cp	cp	NOUN
admet-34	226	18	)	)	PUNCT
admet-34	226	19	in	in	ADP
admet-34	226	20	the	the	DET
admet-34	226	21	case	case	NOUN
admet-34	226	22	of	of	ADP
admet-34	226	23	only	only	ADV
admet-34	226	24	one	one	NUM
admet-34	226	25	spherical	spherical	ADJ
admet-34	226	26	matrix	matrix	NOUN
admet-34	226	27	of	of	ADP
admet-34	226	28	6200	6200	NUM
admet-34	226	29	m	m	PROPN
admet-34	226	30	radius	radius	NOUN
admet-34	226	31	.	.	PUNCT
admet-34	227	1	the	the	DET
admet-34	227	2	initial	initial	ADJ
admet-34	227	3	part	part	NOUN
admet-34	227	4	of	of	ADP
admet-34	227	5	the	the	DET
admet-34	227	6	curve	curve	NOUN
admet-34	227	7	,	,	PUNCT
admet-34	227	8	characterised	characterise	VERB
admet-34	227	9	by	by	ADP
admet-34	227	10	zero	zero	NUM
admet-34	227	11	drug	drug	NOUN
admet-34	227	12	concentration	concentration	NOUN
admet-34	227	13	,	,	PUNCT
admet-34	227	14	is	be	AUX
admet-34	227	15	related	relate	VERB
admet-34	227	16	to	to	ADP
admet-34	227	17	drug	drug	NOUN
admet-34	227	18	residence	residence	NOUN
admet-34	227	19	in	in	ADP
admet-34	227	20	the	the	DET
admet-34	227	21	stomach	stomach	NOUN
admet-34	227	22	where	where	SCONJ
admet-34	227	23	permeability	permeability	NOUN
admet-34	227	24	has	have	AUX
admet-34	227	25	been	be	AUX
admet-34	227	26	set	set	VERB
admet-34	227	27	equal	equal	ADJ
admet-34	227	28	to	to	ADP
admet-34	227	29	zero	zero	NUM
admet-34	227	30	(	(	PUNCT
admet-34	227	31	pgl	pgl	NOUN
admet-34	227	32	=	=	SYM
admet-34	227	33	0	0	NUM
admet-34	227	34	)	)	PUNCT
admet-34	227	35	.	.	PUNCT
admet-34	228	1	then	then	ADV
admet-34	228	2	,	,	PUNCT
admet-34	228	3	cp	cp	INTJ
admet-34	228	4	slowly	slowly	ADV
admet-34	228	5	increases	increase	VERB
admet-34	228	6	to	to	ADP
admet-34	228	7	a	a	DET
admet-34	228	8	maximum	maximum	NOUN
admet-34	228	9	followed	follow	VERB
admet-34	228	10	by	by	ADP
admet-34	228	11	a	a	DET
admet-34	228	12	subsequent	subsequent	ADJ
admet-34	228	13	drop	drop	NOUN
admet-34	228	14	off	off	ADP
admet-34	228	15	till	till	SCONJ
admet-34	228	16	the	the	DET
admet-34	228	17	complete	complete	ADJ
admet-34	228	18	drug	drug	NOUN
admet-34	228	19	disappearance	disappearance	NOUN
admet-34	228	20	from	from	ADP
admet-34	228	21	the	the	DET
admet-34	228	22	plasma	plasma	NOUN
admet-34	228	23	.	.	PUNCT
admet-34	229	1	del	del	PROPN
admet-34	229	2	cont	cont	PROPN
admet-34	229	3	et	et	PROPN
admet-34	229	4	al	al	PROPN
admet-34	229	5	.	.	PROPN
admet-34	229	6	admet	admet	PROPN
admet-34	229	7	&	&	CCONJ
admet-34	229	8	dmpk	dmpk	PROPN
admet-34	229	9	2(2	2(2	NUM
admet-34	229	10	)	)	PUNCT
admet-34	229	11	(	(	PUNCT
admet-34	229	12	2014	2014	NUM
admet-34	229	13	)	)	PUNCT
admet-34	229	14	80	80	NUM
admet-34	229	15	-	-	SYM
admet-34	229	16	97	97	NUM
admet-34	229	17	88	88	NUM
admet-34	229	18	table	table	NOUN
admet-34	229	19	1	1	NUM
admet-34	229	20	.	.	PUNCT
admet-34	229	21	model	model	NOUN
admet-34	229	22	parameters	parameter	NOUN
admet-34	229	23	referring	refer	VERB
admet-34	229	24	to	to	ADP
admet-34	229	25	microcrystalline	microcrystalline	NOUN
admet-34	229	26	theophylline	theophylline	NOUN
admet-34	229	27	(	(	PUNCT
admet-34	229	28	release	release	NOUN
admet-34	229	29	environment	environment	NOUN
admet-34	229	30	vr	vr	NOUN
admet-34	229	31	=	=	NOUN
admet-34	229	32	250	250	NUM
admet-34	229	33	cm	cm	NOUN
admet-34	229	34	3	3	NUM
admet-34	229	35	;	;	PUNCT
admet-34	229	36	polymeric	polymeric	ADJ
admet-34	229	37	carrier	carrier	NOUN
admet-34	229	38	density	density	NOUN
admet-34	229	39	1.2	1.2	NUM
admet-34	229	40	g	g	NOUN
admet-34	229	41	/	/	SYM
admet-34	229	42	cm	cm	NOUN
admet-34	229	43	3	3	NUM
admet-34	229	44	)	)	PUNCT
admet-34	229	45	.	.	PUNCT
admet-34	230	1	pk	pk	NOUN
admet-34	230	2	parameters	parameter	NOUN
admet-34	230	3	[	[	X
admet-34	230	4	10	10	NUM
admet-34	230	5	]	]	SYM
admet-34	230	6	vp(cm3	vp(cm3	NUM
admet-34	230	7	)	)	PUNCT
admet-34	230	8	vl(cm3	vl(cm3	NOUN
admet-34	230	9	)	)	PUNCT
admet-34	230	10	vgics(cm3	vgics(cm3	NOUN
admet-34	230	11	)	)	PUNCT
admet-34	230	12	vt(cm3	vt(cm3	NUM
admet-34	230	13	)	)	PUNCT
admet-34	230	14	11000	11000	NUM
admet-34	230	15	1500	1500	NUM
admet-34	230	16	9.96	9.96	NUM
admet-34	230	17	24000	24000	NUM
admet-34	230	18	qpv(cm3	qpv(cm3	PROPN
admet-34	230	19	/	/	SYM
admet-34	230	20	s	s	PART
admet-34	230	21	)	)	PUNCT
admet-34	230	22	qha(cm3	qha(cm3	PROPN
admet-34	230	23	/	/	SYM
admet-34	230	24	s	s	PART
admet-34	230	25	)	)	PUNCT
admet-34	230	26	qhv(cm3	qhv(cm3	PROPN
admet-34	230	27	/	/	SYM
admet-34	230	28	s	s	PART
admet-34	230	29	)	)	PUNCT
admet-34	230	30	clh(cm3	clh(cm3	PROPN
admet-34	230	31	/	/	SYM
admet-34	230	32	s	s	NOUN
admet-34	230	33	)	)	PUNCT
admet-34	230	34	16.25	16.25	NUM
admet-34	230	35	5.41	5.41	NUM
admet-34	230	36	21.6	21.6	NUM
admet-34	230	37	16.46	16.46	NUM
admet-34	230	38	re	re	NOUN
admet-34	230	39	elk	elk	PROPN
admet-34	230	40	(	(	PUNCT
admet-34	230	41	1	1	NUM
admet-34	230	42	/	/	SYM
admet-34	230	43	s	s	NOUN
admet-34	230	44	)	)	PUNCT
admet-34	230	45	kel(1	kel(1	NOUN
admet-34	230	46	/	/	SYM
admet-34	230	47	s	s	NOUN
admet-34	230	48	)	)	PUNCT
admet-34	230	49	ktp(1	ktp(1	NOUN
admet-34	230	50	/	/	SYM
admet-34	230	51	s	s	NOUN
admet-34	230	52	)	)	PUNCT
admet-34	230	53	ktp(1	ktp(1	NOUN
admet-34	230	54	/	/	SYM
admet-34	230	55	s	s	PROPN
admet-34	230	56	)	)	PUNCT
admet-34	230	57	0.0	0.0	NUM
admet-34	230	58	0.0	0.0	NUM
admet-34	230	59	10	10	NUM
admet-34	230	60	-	-	SYM
admet-34	230	61	6	6	NUM
admet-34	230	62	10	10	NUM
admet-34	230	63	-	-	SYM
admet-34	230	64	6	6	NUM
admet-34	230	65	tgl(s	tgl(s	NOUN
admet-34	230	66	)	)	PUNCT
admet-34	230	67	rgl(cm	rgl(cm	NOUN
admet-34	230	68	)	)	PUNCT
admet-34	231	1	i	i	PRON
admet-34	231	2	glr	glr	PROPN
admet-34	231	3	(	(	PUNCT
admet-34	231	4	cm	cm	NOUN
admet-34	231	5	)	)	PUNCT
admet-34	231	6	pgl(cm	pgl(cm	NOUN
admet-34	231	7	/	/	SYM
admet-34	231	8	s	s	NOUN
admet-34	231	9	)	)	PUNCT
admet-34	231	10	2880	2880	NUM
admet-34	231	11	7.5	7.5	NUM
admet-34	231	12	0.0	0.0	NUM
admet-34	231	13	0.0	0.0	NUM
admet-34	231	14	tsil(s	tsil(s	NOUN
admet-34	231	15	)	)	PUNCT
admet-34	231	16	rsil(cm	rsil(cm	NOUN
admet-34	231	17	)	)	PUNCT
admet-34	232	1	i	i	PRON
admet-34	232	2	silr	silr	NOUN
admet-34	232	3	(	(	PUNCT
admet-34	232	4	cm	cm	NOUN
admet-34	232	5	)	)	PUNCT
admet-34	232	6	psil(cm	psil(cm	NOUN
admet-34	232	7	/	/	SYM
admet-34	232	8	s	s	NOUN
admet-34	232	9	)	)	PUNCT
admet-34	232	10	11520.0	11520.0	NUM
admet-34	232	11	2.5	2.5	NUM
admet-34	232	12	0.0	0.0	NUM
admet-34	232	13	7.0	7.0	NUM
admet-34	232	14	*	*	SYM
admet-34	232	15	10	10	NUM
admet-34	232	16	-	-	SYM
admet-34	232	17	4	4	NUM
admet-34	232	18	til(s	til(s	NOUN
admet-34	232	19	)	)	PUNCT
admet-34	232	20	rlil(cm	rlil(cm	NOUN
admet-34	232	21	)	)	PUNCT
admet-34	233	1	i	i	PRON
admet-34	233	2	lilr	lilr	VERB
admet-34	233	3	(	(	PUNCT
admet-34	233	4	cm	cm	NOUN
admet-34	233	5	)	)	PUNCT
admet-34	233	6	plil(cm	plil(cm	NOUN
admet-34	233	7	/	/	SYM
admet-34	233	8	s	s	PROPN
admet-34	233	9	)	)	PUNCT
admet-34	233	10	115200.0	115200.0	NUM
admet-34	233	11	2.5	2.5	NUM
admet-34	233	12	0.0	0.0	NUM
admet-34	233	13	3.5	3.5	NUM
admet-34	233	14	*	*	SYM
admet-34	233	15	10	10	NUM
admet-34	233	16	-	-	SYM
admet-34	233	17	4	4	NUM
admet-34	233	18	delivery	delivery	NOUN
admet-34	233	19	parameters	parameter	NOUN
admet-34	234	1	[	[	X
admet-34	234	2	11	11	NUM
admet-34	234	3	]	]	X
admet-34	234	4	ceq(g	ceq(g	PROPN
admet-34	234	5	/	/	SYM
admet-34	234	6	cm3	cm3	PROPN
admet-34	234	7	)	)	PUNCT
admet-34	234	8	eq(s	eq(s	NOUN
admet-34	234	9	)	)	PUNCT
admet-34	234	10	deq(cm2	deq(cm2	PROPN
admet-34	234	11	/	/	SYM
admet-34	234	12	s	s	NOUN
admet-34	234	13	)	)	PUNCT
admet-34	234	14	d0(cm2	d0(cm2	PROPN
admet-34	234	15	/	/	SYM
admet-34	234	16	s	s	PROPN
admet-34	234	17	)	)	PUNCT
admet-34	234	18	0.31	0.31	NUM
admet-34	234	19	0.1	0.1	NUM
admet-34	234	20	10	10	NUM
admet-34	234	21	-	-	SYM
admet-34	234	22	7	7	NUM
admet-34	234	23	10	10	NUM
admet-34	234	24	-	-	SYM
admet-34	234	25	8	8	NUM
admet-34	234	26	g(cm3	g(cm3	NOUN
admet-34	234	27	/	/	SYM
admet-34	234	28	g	g	NOUN
admet-34	234	29	)	)	PUNCT
admet-34	234	30	f(cm3	f(cm3	NOUN
admet-34	234	31	/	/	SYM
admet-34	234	32	g	g	NOUN
admet-34	234	33	)	)	PUNCT
admet-34	234	34	dds(cm2	dds(cm2	PROPN
admet-34	234	35	/	/	SYM
admet-34	234	36	s	s	NOUN
admet-34	234	37	)	)	PUNCT
admet-34	234	38	kp(-	kp(-	PROPN
admet-34	234	39	)	)	PUNCT
admet-34	234	40	5.0	5.0	NUM
admet-34	234	41	12.0	12.0	NUM
admet-34	234	42	7.2	7.2	NUM
admet-34	234	43	*	*	NUM
admet-34	234	44	10	10	NUM
admet-34	234	45	-	-	SYM
admet-34	234	46	6	6	NUM
admet-34	234	47	1.0	1.0	NUM
admet-34	234	48	mc	mc	PROPN
admet-34	234	49	sc	sc	PROPN
admet-34	234	50	(	(	PUNCT
admet-34	234	51	g	g	PROPN
admet-34	234	52	/	/	SYM
admet-34	234	53	cm3	cm3	PROPN
admet-34	234	54	)	)	PUNCT
admet-34	234	55	k(1	k(1	PROPN
admet-34	234	56	/	/	SYM
admet-34	234	57	s	s	PROPN
admet-34	234	58	)	)	PUNCT
admet-34	234	59	kr(1	kr(1	PROPN
admet-34	234	60	/	/	SYM
admet-34	234	61	s	s	NOUN
admet-34	234	62	)	)	PUNCT
admet-34	234	63	krb(1	krb(1	PROPN
admet-34	234	64	/	/	SYM
admet-34	234	65	s	s	PROPN
admet-34	234	66	)	)	PUNCT
admet-34	234	67	12495	12495	NUM
admet-34	234	68	1.0	1.0	NUM
admet-34	234	69	0.0	0.0	NUM
admet-34	234	70	0.0	0.0	NUM
admet-34	234	71	the	the	DET
admet-34	234	72	cp	cp	PROPN
admet-34	234	73	increase	increase	NOUN
admet-34	234	74	/	/	SYM
admet-34	234	75	decrease	decrease	NOUN
admet-34	234	76	trend	trend	NOUN
admet-34	234	77	corresponds	correspond	VERB
admet-34	234	78	to	to	ADP
admet-34	234	79	the	the	DET
admet-34	234	80	drug	drug	NOUN
admet-34	234	81	absorption	absorption	NOUN
admet-34	234	82	in	in	ADP
admet-34	234	83	the	the	DET
admet-34	234	84	small	small	ADJ
admet-34	234	85	and	and	CCONJ
admet-34	234	86	large	large	ADJ
admet-34	234	87	intestine	intestine	NOUN
admet-34	234	88	and	and	CCONJ
admet-34	234	89	is	be	AUX
admet-34	234	90	the	the	DET
admet-34	234	91	result	result	NOUN
admet-34	234	92	of	of	ADP
admet-34	234	93	both	both	CCONJ
admet-34	234	94	the	the	DET
admet-34	234	95	simultaneous	simultaneous	ADJ
admet-34	234	96	action	action	NOUN
admet-34	234	97	of	of	ADP
admet-34	234	98	drug	drug	NOUN
admet-34	234	99	release	release	NOUN
admet-34	234	100	from	from	ADP
admet-34	234	101	the	the	DET
admet-34	234	102	matrix	matrix	NOUN
admet-34	234	103	and	and	CCONJ
admet-34	234	104	the	the	DET
admet-34	234	105	following	follow	VERB
admet-34	234	106	adme	adme	NOUN
admet-34	234	107	phenomena	phenomenon	NOUN
admet-34	234	108	.	.	PUNCT
admet-34	235	1	the	the	DET
admet-34	235	2	main	main	ADJ
admet-34	235	3	reason	reason	NOUN
admet-34	235	4	for	for	ADP
admet-34	235	5	the	the	DET
admet-34	235	6	low	low	ADJ
admet-34	235	7	cp	cp	PROPN
admet-34	235	8	values	value	NOUN
admet-34	235	9	is	be	AUX
admet-34	235	10	the	the	DET
admet-34	235	11	very	very	ADV
admet-34	235	12	slow	slow	ADJ
admet-34	235	13	drug	drug	NOUN
admet-34	235	14	delivery	delivery	NOUN
admet-34	235	15	kinetics	kinetic	NOUN
admet-34	235	16	(	(	PUNCT
admet-34	235	17	low	low	ADJ
admet-34	235	18	ratio	ratio	NOUN
admet-34	235	19	between	between	ADP
admet-34	235	20	the	the	DET
admet-34	235	21	release	release	NOUN
admet-34	235	22	surface	surface	NOUN
admet-34	235	23	and	and	CCONJ
admet-34	235	24	the	the	DET
admet-34	235	25	matrix	matrix	NOUN
admet-34	235	26	volume	volume	NOUN
admet-34	235	27	,	,	PUNCT
admet-34	235	28	typical	typical	ADJ
admet-34	235	29	of	of	ADP
admet-34	235	30	big	big	ADJ
admet-34	235	31	spheres	sphere	NOUN
admet-34	235	32	)	)	PUNCT
admet-34	235	33	from	from	ADP
admet-34	235	34	the	the	DET
admet-34	235	35	matrix	matrix	NOUN
admet-34	235	36	as	as	SCONJ
admet-34	235	37	depicted	depict	VERB
admet-34	235	38	in	in	ADP
admet-34	235	39	figure	figure	NOUN
admet-34	235	40	2b	2b	NOUN
admet-34	235	41	(	(	PUNCT
admet-34	235	42	see	see	VERB
admet-34	235	43	the	the	DET
admet-34	235	44	continuous	continuous	ADJ
admet-34	235	45	thick	thick	ADJ
admet-34	235	46	solid	solid	ADJ
admet-34	235	47	line	line	NOUN
admet-34	235	48	;	;	PUNCT
admet-34	235	49	cr	cr	NOUN
admet-34	235	50	indicates	indicate	VERB
admet-34	235	51	the	the	DET
admet-34	235	52	time	time	NOUN
admet-34	235	53	evolution	evolution	NOUN
admet-34	235	54	of	of	ADP
admet-34	235	55	drug	drug	NOUN
admet-34	235	56	concentration	concentration	NOUN
admet-34	235	57	in	in	ADP
admet-34	235	58	release	release	NOUN
admet-34	235	59	environment	environment	NOUN
admet-34	235	60	)	)	PUNCT
admet-34	235	61	.	.	PUNCT
admet-34	236	1	by	by	ADP
admet-34	236	2	keeping	keep	VERB
admet-34	236	3	constant	constant	ADJ
admet-34	236	4	the	the	DET
admet-34	236	5	delivery	delivery	NOUN
admet-34	236	6	system	system	NOUN
admet-34	236	7	volume	volume	NOUN
admet-34	236	8	(	(	PUNCT
admet-34	236	9	1	1	NUM
admet-34	236	10	cm3	cm3	NOUN
admet-34	236	11	)	)	PUNCT
admet-34	236	12	,	,	PUNCT
admet-34	236	13	its	its	PRON
admet-34	236	14	splitting	splitting	NOUN
admet-34	236	15	into	into	ADP
admet-34	236	16	all	all	DET
admet-34	236	17	equal	equal	ADJ
admet-34	236	18	smaller	small	ADJ
admet-34	236	19	particles	particle	NOUN
admet-34	236	20	leads	lead	VERB
admet-34	236	21	to	to	ADP
admet-34	236	22	a	a	DET
admet-34	236	23	much	much	ADV
admet-34	236	24	faster	fast	ADJ
admet-34	236	25	cp	cp	NOUN
admet-34	236	26	increase	increase	NOUN
admet-34	236	27	.	.	PUNCT
admet-34	237	1	in	in	ADP
admet-34	237	2	particular	particular	ADJ
admet-34	237	3	,	,	PUNCT
admet-34	237	4	the	the	DET
admet-34	237	5	thin	thin	ADJ
admet-34	237	6	solid	solid	ADJ
admet-34	237	7	line	line	NOUN
admet-34	237	8	and	and	CCONJ
admet-34	237	9	the	the	DET
admet-34	237	10	dashed	dash	VERB
admet-34	237	11	line	line	NOUN
admet-34	237	12	of	of	ADP
admet-34	237	13	figure	figure	NOUN
admet-34	237	14	2a	2a	PROPN
admet-34	237	15	represent	represent	VERB
admet-34	237	16	,	,	PUNCT
admet-34	237	17	respectively	respectively	ADV
admet-34	237	18	,	,	PUNCT
admet-34	237	19	the	the	DET
admet-34	237	20	cp	cp	NUM
admet-34	237	21	trend	trend	NOUN
admet-34	237	22	referred	refer	VERB
admet-34	237	23	to	to	ADP
admet-34	237	24	particles	particle	NOUN
admet-34	237	25	characterised	characterise	VERB
admet-34	237	26	by	by	ADP
admet-34	237	27	a	a	DET
admet-34	237	28	radius	radius	NOUN
admet-34	237	29	equal	equal	ADJ
admet-34	237	30	to	to	ADP
admet-34	237	31	620	620	NUM
admet-34	237	32	m	m	PROPN
admet-34	237	33	(	(	PUNCT
admet-34	237	34	about	about	ADV
admet-34	237	35	103	103	NUM
admet-34	237	36	particles	particle	NOUN
admet-34	237	37	)	)	PUNCT
admet-34	237	38	and	and	CCONJ
admet-34	237	39	62	62	NUM
admet-34	237	40	m	m	PROPN
admet-34	237	41	(	(	PUNCT
admet-34	237	42	about	about	ADV
admet-34	237	43	106	106	NUM
admet-34	237	44	particles	particle	NOUN
admet-34	237	45	)	)	PUNCT
admet-34	237	46	.	.	PUNCT
admet-34	238	1	it	it	PRON
admet-34	238	2	can	can	AUX
admet-34	238	3	be	be	AUX
admet-34	238	4	seen	see	VERB
admet-34	238	5	that	that	SCONJ
admet-34	238	6	,	,	PUNCT
admet-34	238	7	in	in	ADP
admet-34	238	8	both	both	DET
admet-34	238	9	cases	case	NOUN
admet-34	238	10	,	,	PUNCT
admet-34	238	11	the	the	DET
admet-34	238	12	drugconcentration	drugconcentration	NOUN
admet-34	238	13	rise	rise	NOUN
admet-34	238	14	is	be	AUX
admet-34	238	15	fast	fast	ADJ
admet-34	238	16	and	and	CCONJ
admet-34	238	17	cp	cp	PROPN
admet-34	238	18	reaches	reach	VERB
admet-34	238	19	about	about	ADV
admet-34	238	20	5	5	NUM
admet-34	238	21	g	g	NOUN
admet-34	238	22	/	/	SYM
admet-34	238	23	cm3	cm3	NOUN
admet-34	238	24	after	after	ADP
admet-34	238	25	3.5	3.5	NUM
admet-34	238	26	h	h	NOUN
admet-34	238	27	in	in	ADP
admet-34	238	28	the	the	DET
admet-34	238	29	first	first	ADJ
admet-34	238	30	case	case	NOUN
admet-34	238	31	(	(	PUNCT
admet-34	238	32	620	620	NUM
admet-34	238	33	m	m	NOUN
admet-34	238	34	)	)	PUNCT
admet-34	238	35	and	and	CCONJ
admet-34	238	36	6.5	6.5	NUM
admet-34	238	37	g	g	NOUN
admet-34	238	38	/	/	SYM
admet-34	238	39	cm3	cm3	NOUN
admet-34	238	40	after	after	ADP
admet-34	238	41	2.5	2.5	NUM
admet-34	238	42	h	h	NOUN
admet-34	238	43	in	in	ADP
admet-34	238	44	the	the	DET
admet-34	238	45	second	second	ADJ
admet-34	238	46	case	case	NOUN
admet-34	238	47	(	(	PUNCT
admet-34	238	48	62	62	NUM
admet-34	238	49	m	m	NOUN
admet-34	238	50	)	)	PUNCT
admet-34	238	51	.	.	PUNCT
admet-34	239	1	further	further	ADJ
admet-34	239	2	reductions	reduction	NOUN
admet-34	239	3	of	of	ADP
admet-34	239	4	particles	particle	NOUN
admet-34	239	5	size	size	NOUN
admet-34	239	6	do	do	AUX
admet-34	239	7	not	not	PART
admet-34	239	8	reflect	reflect	VERB
admet-34	239	9	in	in	ADP
admet-34	239	10	an	an	DET
admet-34	239	11	appreciable	appreciable	ADJ
admet-34	239	12	variation	variation	NOUN
admet-34	239	13	of	of	ADP
admet-34	239	14	the	the	DET
admet-34	239	15	cp	cp	PROPN
admet-34	239	16	trend	trend	NOUN
admet-34	239	17	.	.	PUNCT
admet-34	240	1	indeed	indeed	ADV
admet-34	240	2	,	,	PUNCT
admet-34	240	3	as	as	SCONJ
admet-34	240	4	shown	show	VERB
admet-34	240	5	in	in	ADP
admet-34	240	6	figure	figure	NOUN
admet-34	240	7	2b	2b	NOUN
admet-34	240	8	,	,	PUNCT
admet-34	240	9	when	when	SCONJ
admet-34	240	10	particles	particle	NOUN
admet-34	240	11	radius	radius	NOUN
admet-34	240	12	is	be	AUX
admet-34	240	13	around	around	ADV
admet-34	240	14	62	62	NUM
admet-34	240	15	m	m	PROPN
admet-34	240	16	,	,	PUNCT
admet-34	240	17	the	the	DET
admet-34	240	18	drug	drug	NOUN
admet-34	240	19	,	,	PUNCT
admet-34	240	20	totally	totally	ADV
admet-34	240	21	,	,	PUNCT
admet-34	240	22	and	and	CCONJ
admet-34	240	23	very	very	ADV
admet-34	240	24	rapidly	rapidly	ADV
admet-34	240	25	,	,	PUNCT
admet-34	240	26	dissolves	dissolve	VERB
admet-34	240	27	in	in	ADP
admet-34	240	28	the	the	DET
admet-34	240	29	release	release	NOUN
admet-34	240	30	environment	environment	NOUN
admet-34	240	31	(	(	PUNCT
admet-34	240	32	stomach	stomach	NOUN
admet-34	240	33	fluids	fluid	NOUN
admet-34	240	34	)	)	PUNCT
admet-34	240	35	to	to	PART
admet-34	240	36	get	get	VERB
admet-34	240	37	the	the	DET
admet-34	240	38	maximum	maximum	ADJ
admet-34	240	39	value	value	NOUN
admet-34	240	40	compatible	compatible	ADJ
admet-34	240	41	with	with	ADP
admet-34	240	42	the	the	DET
admet-34	240	43	administered	administer	VERB
admet-34	240	44	dose	dose	NOUN
admet-34	240	45	,	,	PUNCT
admet-34	240	46	i.e.	i.e.	X
admet-34	240	47	400	400	NUM
admet-34	240	48	g	g	NOUN
admet-34	240	49	/	/	SYM
admet-34	240	50	cm3	cm3	NOUN
admet-34	240	51	.	.	PUNCT
admet-34	241	1	in	in	ADP
admet-34	241	2	this	this	DET
admet-34	241	3	case	case	NOUN
admet-34	241	4	,	,	PUNCT
admet-34	241	5	no	no	DET
admet-34	241	6	control	control	NOUN
admet-34	241	7	on	on	ADP
admet-34	241	8	drug	drug	NOUN
admet-34	241	9	release	release	NOUN
admet-34	241	10	is	be	AUX
admet-34	241	11	exerted	exert	VERB
admet-34	241	12	and	and	CCONJ
admet-34	241	13	the	the	DET
admet-34	241	14	delivery	delivery	NOUN
admet-34	241	15	system	system	NOUN
admet-34	241	16	simply	simply	ADV
admet-34	241	17	ensures	ensure	VERB
admet-34	241	18	a	a	DET
admet-34	241	19	prompt	prompt	ADJ
admet-34	241	20	and	and	CCONJ
admet-34	241	21	total	total	ADJ
admet-34	241	22	release	release	NOUN
admet-34	241	23	in	in	ADP
admet-34	241	24	the	the	DET
admet-34	241	25	stomach	stomach	NOUN
admet-34	241	26	.	.	PUNCT
admet-34	242	1	in	in	ADP
admet-34	242	2	other	other	ADJ
admet-34	242	3	words	word	NOUN
admet-34	242	4	,	,	PUNCT
admet-34	242	5	no	no	DET
admet-34	242	6	differences	difference	NOUN
admet-34	242	7	occur	occur	VERB
admet-34	242	8	in	in	ADP
admet-34	242	9	the	the	DET
admet-34	242	10	cp	cp	NOUN
admet-34	242	11	trend	trend	NOUN
admet-34	242	12	induced	induce	VERB
admet-34	242	13	by	by	ADP
admet-34	242	14	this	this	DET
admet-34	242	15	formulation	formulation	NOUN
admet-34	242	16	or	or	CCONJ
admet-34	242	17	by	by	ADP
admet-34	242	18	a	a	DET
admet-34	242	19	drug	drug	NOUN
admet-34	242	20	solution	solution	NOUN
admet-34	242	21	of	of	ADP
admet-34	242	22	the	the	DET
admet-34	242	23	same	same	ADJ
admet-34	242	24	dose	dose	NOUN
admet-34	242	25	.	.	PUNCT
admet-34	243	1	it	it	PRON
admet-34	243	2	is	be	AUX
admet-34	243	3	worth	worth	ADJ
admet-34	243	4	mentioning	mention	VERB
admet-34	243	5	that	that	SCONJ
admet-34	243	6	the	the	DET
admet-34	243	7	cp	cp	NOUN
admet-34	243	8	trend	trend	NOUN
admet-34	243	9	of	of	ADP
admet-34	243	10	the	the	DET
admet-34	243	11	62	62	NUM
admet-34	243	12	m	m	PROPN
admet-34	243	13	particles	particle	NOUN
admet-34	243	14	can	can	AUX
admet-34	243	15	be	be	AUX
admet-34	243	16	approximately	approximately	ADV
admet-34	243	17	obtained	obtain	VERB
admet-34	243	18	by	by	ADP
admet-34	243	19	adopting	adopt	VERB
admet-34	243	20	an	an	DET
admet-34	243	21	ensemble	ensemble	NOUN
admet-34	243	22	of	of	ADP
admet-34	243	23	poly	poly	NOUN
admet-34	243	24	-	-	PUNCT
admet-34	243	25	dispersed	disperse	VERB
admet-34	243	26	particles	particle	NOUN
admet-34	243	27	described	describe	VERB
admet-34	243	28	by	by	ADP
admet-34	243	29	eq.(9	eq.(9	ADJ
admet-34	243	30	)	)	PUNCT
admet-34	243	31	considering	consider	VERB
admet-34	243	32	the	the	DET
admet-34	243	33	following	follow	VERB
admet-34	243	34	parameters	parameter	NOUN
admet-34	243	35	:	:	PUNCT
admet-34	243	36			PUNCT
admet-34	243	37	=	=	SYM
admet-34	243	38	1000	1000	NUM
admet-34	243	39	m	m	PROPN
admet-34	243	40	,	,	PUNCT
admet-34	243	41			NOUN
admet-34	243	42	=	=	SYM
admet-34	243	43	2	2	NUM
admet-34	243	44	,	,	PUNCT
admet-34	243	45	rmin	rmin	NOUN
admet-34	243	46	=	=	SYM
admet-34	243	47	0	0	NUM
admet-34	243	48	m	m	PROPN
admet-34	243	49	and	and	CCONJ
admet-34	243	50	rmax	rmax	ADJ
admet-34	243	51	=	=	SYM
admet-34	243	52	1200	1200	NUM
admet-34	243	53	m	m	PROPN
admet-34	243	54	(	(	PUNCT
admet-34	243	55	see	see	VERB
admet-34	243	56	the	the	DET
admet-34	243	57	grey	grey	ADJ
admet-34	243	58	line	line	NOUN
admet-34	243	59	in	in	ADP
admet-34	243	60	figure	figure	NOUN
admet-34	243	61	2a	2a	NUM
admet-34	243	62	)	)	PUNCT
admet-34	243	63	.	.	PUNCT
admet-34	244	1	the	the	DET
admet-34	244	2	difference	difference	NOUN
admet-34	244	3	of	of	ADP
admet-34	244	4	using	use	VERB
admet-34	244	5	a	a	DET
admet-34	244	6	poly	poly	ADJ
admet-34	244	7	-	-	PUNCT
admet-34	244	8	dispersed	disperse	VERB
admet-34	244	9	distribution	distribution	NOUN
admet-34	244	10	relies	rely	VERB
admet-34	244	11	on	on	ADP
admet-34	244	12	a	a	DET
admet-34	244	13	smaller	small	ADJ
admet-34	244	14	drug	drug	NOUN
admet-34	244	15	concentration	concentration	NOUN
admet-34	244	16	(	(	PUNCT
admet-34	244	17	cr	cr	NOUN
admet-34	244	18	,	,	PUNCT
admet-34	244	19	see	see	VERB
admet-34	244	20	grey	grey	ADJ
admet-34	244	21	line	line	NOUN
admet-34	244	22	in	in	ADP
admet-34	244	23	figure	figure	NOUN
admet-34	244	24	2b	2b	NOUN
admet-34	244	25	)	)	PUNCT
admet-34	244	26	in	in	ADP
admet-34	244	27	the	the	DET
admet-34	244	28	stomach	stomach	NOUN
admet-34	244	29	fluids	fluid	NOUN
admet-34	244	30	,	,	PUNCT
admet-34	244	31	which	which	PRON
admet-34	244	32	is	be	AUX
admet-34	244	33	advantageous	advantageous	ADJ
admet-34	244	34	in	in	ADP
admet-34	244	35	the	the	DET
admet-34	244	36	case	case	NOUN
admet-34	244	37	of	of	ADP
admet-34	244	38	stomach	stomach	NOUN
admet-34	244	39	wall	wall	VERB
admet-34	244	40	aggressive	aggressive	ADJ
admet-34	244	41	drugs	drug	NOUN
admet-34	244	42	.	.	PUNCT
admet-34	245	1	admet	admet	PROPN
admet-34	245	2	&	&	CCONJ
admet-34	245	3	dmpk	dmpk	PROPN
admet-34	245	4	2(2	2(2	NUM
admet-34	245	5	)	)	PUNCT
admet-34	245	6	(	(	PUNCT
admet-34	245	7	2014	2014	NUM
admet-34	245	8	)	)	PUNCT
admet-34	245	9	80	80	NUM
admet-34	245	10	-	-	SYM
admet-34	245	11	97	97	NUM
admet-34	245	12	in	in	ADP
admet-34	245	13	vivo	vivo	ADJ
admet-34	245	14	drug	drug	NOUN
admet-34	245	15	release	release	NOUN
admet-34	245	16	and	and	CCONJ
admet-34	245	17	absorption	absorption	NOUN
admet-34	245	18	doi	doi	NOUN
admet-34	245	19	:	:	PUNCT
admet-34	245	20	10.5599	10.5599	NUM
admet-34	245	21	/	/	SYM
admet-34	245	22	admet.2.2.34	admet.2.2.34	PROPN
admet-34	245	23	89	89	NUM
admet-34	245	24	finally	finally	ADV
admet-34	245	25	,	,	PUNCT
admet-34	245	26	it	it	PRON
admet-34	245	27	is	be	AUX
admet-34	245	28	worthwhile	worthwhile	ADJ
admet-34	245	29	underlying	underlying	ADJ
admet-34	245	30	that	that	SCONJ
admet-34	245	31	,	,	PUNCT
admet-34	245	32	based	base	VERB
admet-34	245	33	on	on	ADP
admet-34	245	34	the	the	DET
admet-34	245	35	pk	pk	NOUN
admet-34	245	36	parameters	parameter	NOUN
admet-34	245	37	set	set	VERB
admet-34	245	38	in	in	ADP
admet-34	245	39	table	table	NOUN
admet-34	245	40	1	1	NUM
admet-34	245	41	,	,	PUNCT
admet-34	245	42	the	the	DET
admet-34	245	43	time	time	NOUN
admet-34	245	44	evolution	evolution	NOUN
admet-34	245	45	of	of	ADP
admet-34	245	46	drug	drug	NOUN
admet-34	245	47	concentration	concentration	NOUN
admet-34	245	48	in	in	ADP
admet-34	245	49	the	the	DET
admet-34	245	50	cigs	cig	NOUN
admet-34	245	51	(	(	PUNCT
admet-34	245	52	cgics	cgic	NOUN
admet-34	245	53	)	)	PUNCT
admet-34	245	54	and	and	CCONJ
admet-34	245	55	in	in	ADP
admet-34	245	56	the	the	DET
admet-34	245	57	liver	liver	NOUN
admet-34	245	58	(	(	PUNCT
admet-34	245	59	cl	cl	NOUN
admet-34	245	60	)	)	PUNCT
admet-34	245	61	is	be	AUX
admet-34	245	62	substantially	substantially	ADV
admet-34	245	63	equal	equal	ADJ
admet-34	245	64	to	to	ADP
admet-34	245	65	that	that	PRON
admet-34	245	66	of	of	ADP
admet-34	245	67	cp	cp	PROPN
admet-34	245	68	.	.	PUNCT
admet-34	246	1	this	this	PRON
admet-34	246	2	depends	depend	VERB
admet-34	246	3	on	on	ADP
admet-34	246	4	the	the	DET
admet-34	246	5	small	small	ADJ
admet-34	246	6	cigs	cig	NOUN
admet-34	246	7	(	(	PUNCT
admet-34	246	8	vgics	vgic	NOUN
admet-34	246	9	=	=	SYM
admet-34	246	10	10	10	NUM
admet-34	246	11	cm3	cm3	NOUN
admet-34	246	12	)	)	PUNCT
admet-34	246	13	and	and	CCONJ
admet-34	246	14	liver	liver	NOUN
admet-34	246	15	(	(	PUNCT
admet-34	246	16	vl	vl	NOUN
admet-34	246	17	=	=	SYM
admet-34	246	18	1500	1500	NUM
admet-34	246	19	cm3	cm3	NOUN
admet-34	246	20	)	)	PUNCT
admet-34	246	21	volume	volume	NOUN
admet-34	246	22	in	in	ADP
admet-34	246	23	comparison	comparison	NOUN
admet-34	246	24	to	to	ADP
admet-34	246	25	the	the	DET
admet-34	246	26	plasma	plasma	NOUN
admet-34	246	27	(	(	PUNCT
admet-34	246	28	vp	vp	NOUN
admet-34	246	29	=	=	SYM
admet-34	246	30	11000	11000	NUM
admet-34	246	31	cm	cm	NOUN
admet-34	246	32	3	3	NUM
admet-34	246	33	)	)	PUNCT
admet-34	246	34	and	and	CCONJ
admet-34	246	35	tissues	tissue	NOUN
admet-34	246	36	(	(	PUNCT
admet-34	246	37	vt	vt	NOUN
admet-34	246	38	=	=	NOUN
admet-34	246	39	24000	24000	NUM
admet-34	246	40	cm	cm	NOUN
admet-34	246	41	3	3	NUM
admet-34	246	42	)	)	PUNCT
admet-34	246	43	volumes	volume	NOUN
admet-34	246	44	and	and	CCONJ
admet-34	246	45	the	the	DET
admet-34	246	46	relatively	relatively	ADV
admet-34	246	47	high	high	ADJ
admet-34	246	48	volumetric	volumetric	NOUN
admet-34	246	49	flow	flow	NOUN
admet-34	246	50	connecting	connect	VERB
admet-34	246	51	the	the	DET
admet-34	246	52	various	various	ADJ
admet-34	246	53	compartments	compartment	NOUN
admet-34	246	54	(	(	PUNCT
admet-34	246	55	qhv	qhv	PROPN
admet-34	246	56	,	,	PUNCT
admet-34	246	57	qpv	qpv	PROPN
admet-34	246	58	and	and	CCONJ
admet-34	246	59	qha	qha	NOUN
admet-34	246	60	;	;	PUNCT
admet-34	246	61	see	see	VERB
admet-34	246	62	figure	figure	NOUN
admet-34	246	63	1	1	NUM
admet-34	246	64	and	and	CCONJ
admet-34	246	65	table	table	NOUN
admet-34	246	66	1	1	NUM
admet-34	246	67	)	)	PUNCT
admet-34	246	68	.	.	PUNCT
admet-34	247	1	figure	figure	NOUN
admet-34	247	2	2	2	NUM
admet-34	247	3	.	.	PUNCT
admet-34	248	1	(	(	PUNCT
admet-34	248	2	a	a	X
admet-34	248	3	)	)	PUNCT
admet-34	248	4	theophylline	theophylline	NOUN
admet-34	248	5	plasma	plasma	NOUN
admet-34	248	6	concentration	concentration	NOUN
admet-34	248	7	cp	cp	INTJ
admet-34	248	8	referring	refer	VERB
admet-34	248	9	to	to	ADP
admet-34	248	10	different	different	ADJ
admet-34	248	11	spherical	spherical	ADJ
admet-34	248	12	delivery	delivery	NOUN
admet-34	248	13	systems	system	NOUN
admet-34	248	14	characterized	characterize	VERB
admet-34	248	15	by	by	ADP
admet-34	248	16	the	the	DET
admet-34	248	17	same	same	ADJ
admet-34	248	18	volume	volume	NOUN
admet-34	248	19	(	(	PUNCT
admet-34	248	20	1	1	NUM
admet-34	248	21	cm	cm	NOUN
admet-34	248	22	3	3	NUM
admet-34	248	23	)	)	PUNCT
admet-34	248	24	and	and	CCONJ
admet-34	248	25	dose	dose	VERB
admet-34	248	26	(	(	PUNCT
admet-34	248	27	100	100	NUM
admet-34	248	28	mg	mg	NUM
admet-34	248	29	)	)	PUNCT
admet-34	248	30	.	.	PUNCT
admet-34	249	1	the	the	DET
admet-34	249	2	number	number	NOUN
admet-34	249	3	close	close	ADJ
admet-34	249	4	to	to	ADP
admet-34	249	5	the	the	DET
admet-34	249	6	curves	curve	NOUN
admet-34	249	7	indicates	indicate	VERB
admet-34	249	8	the	the	DET
admet-34	249	9	diameter	diameter	NOUN
admet-34	249	10	of	of	ADP
admet-34	249	11	the	the	DET
admet-34	249	12	sphere(s	sphere(s	NOUN
admet-34	249	13	)	)	PUNCT
admet-34	249	14	considered	consider	VERB
admet-34	249	15	while	while	SCONJ
admet-34	249	16	the	the	DET
admet-34	249	17	gray	gray	ADJ
admet-34	249	18	line	line	NOUN
admet-34	249	19	refers	refer	VERB
admet-34	249	20	to	to	ADP
admet-34	249	21	a	a	DET
admet-34	249	22	poly	poly	ADJ
admet-34	249	23	-	-	PUNCT
admet-34	249	24	disperse	disperse	NOUN
admet-34	249	25	ensemble	ensemble	NOUN
admet-34	249	26	of	of	ADP
admet-34	249	27	spherical	spherical	ADJ
admet-34	249	28	particles	particle	NOUN
admet-34	249	29	whose	whose	DET
admet-34	249	30	diameter	diameter	NOUN
admet-34	249	31	spans	span	VERB
admet-34	249	32	from	from	ADP
admet-34	249	33	0	0	NUM
admet-34	249	34	to	to	ADP
admet-34	249	35	1240	1240	NUM
admet-34	249	36	m	m	PROPN
admet-34	249	37	.	.	PUNCT
admet-34	250	1	(	(	PUNCT
admet-34	250	2	b	b	X
admet-34	250	3	)	)	PUNCT
admet-34	250	4	theophylline	theophylline	ADJ
admet-34	250	5	concentration	concentration	NOUN
admet-34	250	6	in	in	ADP
admet-34	250	7	the	the	DET
admet-34	250	8	release	release	NOUN
admet-34	250	9	environment	environment	NOUN
admet-34	250	10	(	(	PUNCT
admet-34	250	11	cr	cr	NOUN
admet-34	250	12	)	)	PUNCT
admet-34	250	13	referring	refer	VERB
admet-34	250	14	to	to	ADP
admet-34	250	15	the	the	DET
admet-34	250	16	four	four	NUM
admet-34	250	17	delivery	delivery	NOUN
admet-34	250	18	systems	system	NOUN
admet-34	250	19	shown	show	VERB
admet-34	250	20	in	in	ADP
admet-34	250	21	(	(	PUNCT
admet-34	250	22	a	a	NOUN
admet-34	250	23	)	)	PUNCT
admet-34	250	24	.	.	PUNCT
admet-34	251	1	in	in	ADP
admet-34	251	2	the	the	DET
admet-34	251	3	6200	6200	NUM
admet-34	251	4	m	m	PROPN
admet-34	251	5	,	,	PUNCT
admet-34	251	6	620	620	NUM
admet-34	251	7	m	m	PROPN
admet-34	251	8	and	and	CCONJ
admet-34	251	9	62	62	NUM
admet-34	251	10	m	m	PROPN
admet-34	251	11	cases	case	NOUN
admet-34	251	12	,	,	PUNCT
admet-34	251	13	the	the	DET
admet-34	251	14	numerical	numerical	ADJ
admet-34	251	15	solution	solution	NOUN
admet-34	251	16	of	of	ADP
admet-34	251	17	the	the	DET
admet-34	251	18	model	model	NOUN
admet-34	251	19	implied	imply	VERB
admet-34	251	20	the	the	DET
admet-34	251	21	subdivision	subdivision	NOUN
admet-34	251	22	of	of	ADP
admet-34	251	23	the	the	DET
admet-34	251	24	generic	generic	ADJ
admet-34	251	25	particle	particle	NOUN
admet-34	251	26	in	in	ADP
admet-34	251	27	500	500	NUM
admet-34	251	28	control	control	NOUN
admet-34	251	29	volumes	volume	NOUN
admet-34	251	30	.	.	PUNCT
admet-34	252	1	in	in	ADP
admet-34	252	2	the	the	DET
admet-34	252	3	0	0	NUM
admet-34	252	4	to	to	ADP
admet-34	252	5	1240	1240	NUM
admet-34	252	6	m	m	PROPN
admet-34	252	7	case	case	NOUN
admet-34	252	8	,	,	PUNCT
admet-34	252	9	the	the	DET
admet-34	252	10	distribution	distribution	NOUN
admet-34	252	11	was	be	AUX
admet-34	252	12	subdivided	subdivide	VERB
admet-34	252	13	in	in	ADP
admet-34	252	14	10	10	NUM
admet-34	252	15	classes	class	NOUN
admet-34	252	16	and	and	CCONJ
admet-34	252	17	15	15	NUM
admet-34	252	18	control	control	NOUN
admet-34	252	19	volumes	volume	NOUN
admet-34	252	20	were	be	AUX
admet-34	252	21	considered	consider	VERB
admet-34	252	22	for	for	ADP
admet-34	252	23	the	the	DET
admet-34	252	24	generic	generic	ADJ
admet-34	252	25	particle	particle	NOUN
admet-34	252	26	of	of	ADP
admet-34	252	27	each	each	DET
admet-34	252	28	class	class	NOUN
admet-34	252	29	.	.	PUNCT
admet-34	253	1	on	on	ADP
admet-34	253	2	the	the	DET
admet-34	253	3	contrary	contrary	NOUN
admet-34	253	4	,	,	PUNCT
admet-34	253	5	drug	drug	NOUN
admet-34	253	6	concentration	concentration	NOUN
admet-34	253	7	(	(	PUNCT
admet-34	253	8	ct	ct	NOUN
admet-34	253	9	)	)	PUNCT
admet-34	253	10	in	in	ADP
admet-34	253	11	the	the	DET
admet-34	253	12	scarcely	scarcely	ADV
admet-34	253	13	perfused	perfused	ADJ
admet-34	253	14	tissues	tissue	NOUN
admet-34	253	15	and	and	CCONJ
admet-34	253	16	organs	organ	NOUN
admet-34	253	17	(	(	PUNCT
admet-34	253	18	tissues	tissue	NOUN
admet-34	253	19	in	in	ADP
admet-34	253	20	figure	figure	NOUN
admet-34	253	21	1	1	NUM
admet-34	253	22	)	)	PUNCT
admet-34	253	23	monotonically	monotonically	ADV
admet-34	253	24	increases	increase	VERB
admet-34	253	25	reaching	reach	VERB
admet-34	253	26	,	,	PUNCT
admet-34	253	27	for	for	ADP
admet-34	253	28	all	all	DET
admet-34	253	29	formulations	formulation	NOUN
admet-34	253	30	,	,	PUNCT
admet-34	253	31	values	value	NOUN
admet-34	253	32	that	that	PRON
admet-34	253	33	are	be	AUX
admet-34	253	34	about	about	ADV
admet-34	253	35	two	two	NUM
admet-34	253	36	orders	order	NOUN
admet-34	253	37	of	of	ADP
admet-34	253	38	magnitude	magnitude	NOUN
admet-34	253	39	smaller	small	ADJ
admet-34	253	40	than	than	ADP
admet-34	253	41	cp	cp	PROPN
admet-34	253	42	.	.	PUNCT
admet-34	254	1	this	this	PRON
admet-34	254	2	is	be	AUX
admet-34	254	3	essentially	essentially	ADV
admet-34	254	4	due	due	ADJ
admet-34	254	5	to	to	ADP
admet-34	254	6	the	the	DET
admet-34	254	7	high	high	ADJ
admet-34	254	8	value	value	NOUN
admet-34	254	9	of	of	ADP
admet-34	254	10	tissues	tissue	NOUN
admet-34	254	11	volumes	volume	NOUN
admet-34	254	12	(	(	PUNCT
admet-34	254	13	vt	vt	NOUN
admet-34	254	14	=	=	NOUN
admet-34	254	15	24000	24000	NUM
admet-34	254	16	cm	cm	NOUN
admet-34	254	17	3	3	NUM
admet-34	254	18	)	)	PUNCT
admet-34	254	19	.	.	PUNCT
admet-34	255	1	interestingly	interestingly	ADV
admet-34	255	2	,	,	PUNCT
admet-34	255	3	for	for	ADP
admet-34	255	4	smaller	small	ADJ
admet-34	255	5	particles	particle	NOUN
admet-34	255	6	,	,	PUNCT
admet-34	255	7	cp	cp	PROPN
admet-34	255	8	falls	fall	VERB
admet-34	255	9	inside	inside	ADP
admet-34	255	10	the	the	DET
admet-34	255	11	theophylline	theophylline	NOUN
admet-34	255	12	therapeutic	therapeutic	ADJ
admet-34	255	13	window	window	NOUN
admet-34	255	14	that	that	PRON
admet-34	255	15	corresponds	correspond	VERB
admet-34	255	16	to	to	ADP
admet-34	255	17	5	5	NUM
admet-34	255	18	–	–	SYM
admet-34	255	19	15	15	NUM
admet-34	255	20	g	g	PROPN
admet-34	255	21	/	/	SYM
admet-34	255	22	cm3	cm3	NOUN
admet-34	255	23	.	.	PUNCT
admet-34	256	1	the	the	DET
admet-34	256	2	second	second	ADJ
admet-34	256	3	drug	drug	NOUN
admet-34	256	4	considered	consider	VERB
admet-34	256	5	,	,	PUNCT
admet-34	256	6	temazepam	temazepam	PROPN
admet-34	256	7	(	(	PUNCT
admet-34	256	8	tem	tem	PROPN
admet-34	256	9	)	)	PUNCT
admet-34	256	10	,	,	PUNCT
admet-34	256	11	a	a	DET
admet-34	256	12	benzodiazepine	benzodiazepine	NOUN
admet-34	256	13	derivative	derivative	NOUN
admet-34	256	14	characterised	characterise	VERB
admet-34	256	15	by	by	ADP
admet-34	256	16	sedative	sedative	ADJ
admet-34	256	17	and	and	CCONJ
admet-34	256	18	hypnotic	hypnotic	ADJ
admet-34	256	19	actions	action	NOUN
admet-34	256	20	,	,	PUNCT
admet-34	256	21	was	be	AUX
admet-34	256	22	chosen	choose	VERB
admet-34	256	23	for	for	ADP
admet-34	256	24	the	the	DET
admet-34	256	25	possibility	possibility	NOUN
admet-34	256	26	of	of	ADP
admet-34	256	27	loading	load	VERB
admet-34	256	28	it	it	PRON
admet-34	256	29	into	into	ADP
admet-34	256	30	a	a	DET
admet-34	256	31	polymeric	polymeric	ADJ
admet-34	256	32	carrier	carrier	NOUN
admet-34	256	33	(	(	PUNCT
admet-34	256	34	such	such	ADJ
admet-34	256	35	as	as	ADP
admet-34	256	36	crosslinked	crosslinked	ADJ
admet-34	256	37	polyvinyl	polyvinyl	NOUN
admet-34	256	38	-	-	PUNCT
admet-34	256	39	pyrrolidone	pyrrolidone	VERB
admet-34	256	40	particles	particle	NOUN
admet-34	256	41	)	)	PUNCT
admet-34	256	42	in	in	ADP
admet-34	256	43	a	a	DET
admet-34	256	44	completely	completely	ADV
admet-34	256	45	amorphous	amorphous	ADJ
admet-34	256	46	form	form	NOUN
admet-34	256	47	[	[	X
admet-34	256	48	11	11	NUM
admet-34	256	49	]	]	PUNCT
admet-34	256	50	.	.	PUNCT
admet-34	257	1	this	this	PRON
admet-34	257	2	,	,	PUNCT
admet-34	257	3	of	of	ADP
admet-34	257	4	course	course	NOUN
admet-34	257	5	,	,	PUNCT
admet-34	257	6	can	can	AUX
admet-34	257	7	be	be	AUX
admet-34	257	8	highly	highly	ADV
admet-34	257	9	advantageous	advantageous	ADJ
admet-34	257	10	as	as	SCONJ
admet-34	257	11	amorphous	amorphous	ADJ
admet-34	257	12	tem	tem	PROPN
admet-34	257	13	is	be	AUX
admet-34	257	14	characterised	characterise	VERB
admet-34	257	15	by	by	ADP
admet-34	257	16	a	a	DET
admet-34	257	17	much	much	ADV
admet-34	257	18	higher	high	ADJ
admet-34	257	19	solubility	solubility	NOUN
admet-34	257	20	(	(	PUNCT
admet-34	257	21	≈	≈	PROPN
admet-34	257	22	8649	8649	NUM
admet-34	257	23	g	g	PROPN
admet-34	257	24	/	/	SYM
admet-34	257	25	cm3	cm3	NOUN
admet-34	257	26	)	)	PUNCT
admet-34	257	27	with	with	ADP
admet-34	257	28	respect	respect	NOUN
admet-34	257	29	to	to	ADP
admet-34	257	30	the	the	DET
admet-34	257	31	original	original	ADJ
admet-34	257	32	macro	macro	NOUN
admet-34	257	33	-	-	NOUN
admet-34	257	34	crystal	crystal	NOUN
admet-34	257	35	solubility	solubility	NOUN
admet-34	257	36	(	(	PUNCT
admet-34	257	37	≈	≈	PROPN
admet-34	257	38	164	164	NUM
admet-34	257	39	g	g	PROPN
admet-34	257	40	/	/	SYM
admet-34	257	41	cm3	cm3	NOUN
admet-34	257	42	)	)	PUNCT
admet-34	257	43	.	.	PUNCT
admet-34	258	1	accordingly	accordingly	ADV
admet-34	258	2	,	,	PUNCT
admet-34	258	3	we	we	PRON
admet-34	258	4	would	would	AUX
admet-34	258	5	like	like	VERB
admet-34	258	6	to	to	PART
admet-34	258	7	theoretically	theoretically	ADV
admet-34	258	8	evaluate	evaluate	VERB
admet-34	258	9	the	the	DET
admet-34	258	10	pk	pk	NOUN
admet-34	258	11	advantage	advantage	NOUN
admet-34	258	12	of	of	ADP
admet-34	258	13	using	use	VERB
admet-34	258	14	amorphous	amorphous	ADJ
admet-34	258	15	tem	tem	NOUN
admet-34	258	16	in	in	ADP
admet-34	258	17	place	place	NOUN
admet-34	258	18	of	of	ADP
admet-34	258	19	its	its	PRON
admet-34	258	20	native	native	ADJ
admet-34	258	21	macro	macro	NOUN
admet-34	258	22	-	-	NOUN
admet-34	258	23	crystal	crystal	NOUN
admet-34	258	24	condition	condition	NOUN
admet-34	258	25	.	.	PUNCT
admet-34	259	1	in	in	ADP
admet-34	259	2	absence	absence	NOUN
admet-34	259	3	of	of	ADP
admet-34	259	4	precise	precise	ADJ
admet-34	259	5	values	value	NOUN
admet-34	259	6	of	of	ADP
admet-34	259	7	tem	tem	PROPN
admet-34	259	8	pk	pk	PROPN
admet-34	259	9	parameters	parameter	NOUN
admet-34	259	10	,	,	PUNCT
admet-34	259	11	we	we	PRON
admet-34	259	12	adopted	adopt	VERB
admet-34	259	13	those	those	PRON
admet-34	259	14	of	of	ADP
admet-34	259	15	a	a	DET
admet-34	259	16	similar	similar	ADJ
admet-34	259	17	drug	drug	NOUN
admet-34	259	18	[	[	X
admet-34	259	19	10	10	NUM
admet-34	259	20	]	]	PUNCT
admet-34	259	21	while	while	SCONJ
admet-34	259	22	all	all	DET
admet-34	259	23	other	other	ADJ
admet-34	259	24	model	model	NOUN
admet-34	259	25	parameters	parameter	NOUN
admet-34	259	26	were	be	AUX
admet-34	259	27	set	set	VERB
admet-34	259	28	according	accord	VERB
admet-34	259	29	to	to	ADP
admet-34	259	30	our	our	PRON
admet-34	259	31	previous	previous	ADJ
admet-34	259	32	study	study	NOUN
admet-34	260	1	[	[	X
admet-34	260	2	11	11	NUM
admet-34	260	3	]	]	PUNCT
admet-34	260	4	(	(	PUNCT
admet-34	260	5	see	see	VERB
admet-34	260	6	table	table	NOUN
admet-34	260	7	2	2	NUM
admet-34	260	8	)	)	PUNCT
admet-34	260	9	.	.	PUNCT
admet-34	261	1	figure	figure	NOUN
admet-34	261	2	3a	3a	PROPN
admet-34	261	3	makes	make	VERB
admet-34	261	4	clear	clear	ADJ
admet-34	261	5	that	that	SCONJ
admet-34	261	6	amorphous	amorphous	ADJ
admet-34	261	7	tem	tem	PROPN
admet-34	261	8	(	(	PUNCT
admet-34	261	9	thick	thick	ADJ
admet-34	261	10	line	line	NOUN
admet-34	261	11	)	)	PUNCT
admet-34	261	12	shows	show	NOUN
admet-34	261	13	,	,	PUNCT
admet-34	261	14	in	in	ADP
admet-34	261	15	pk	pk	NOUN
admet-34	261	16	terms	term	NOUN
admet-34	261	17	,	,	PUNCT
admet-34	261	18	a	a	DET
admet-34	261	19	better	well	ADJ
admet-34	261	20	performance	performance	NOUN
admet-34	261	21	with	with	ADP
admet-34	261	22	respect	respect	NOUN
admet-34	261	23	to	to	ADP
admet-34	261	24	crystalline	crystalline	PROPN
admet-34	261	25	tem	tem	PROPN
admet-34	261	26	(	(	PUNCT
admet-34	261	27	thin	thin	ADJ
admet-34	261	28	line	line	NOUN
admet-34	261	29	)	)	PUNCT
admet-34	261	30	.	.	PUNCT
admet-34	262	1	indeed	indeed	ADV
admet-34	262	2	,	,	PUNCT
admet-34	262	3	not	not	PART
admet-34	262	4	only	only	ADV
admet-34	262	5	it	it	PRON
admet-34	262	6	yields	yield	VERB
admet-34	262	7	to	to	ADP
admet-34	262	8	a	a	DET
admet-34	262	9	higher	high	ADJ
admet-34	262	10	maximum	maximum	NOUN
admet-34	262	11	cp	cp	INTJ
admet-34	262	12	(	(	PUNCT
admet-34	262	13	0.16	0.16	NUM
admet-34	262	14	g	g	PROPN
admet-34	262	15	/	/	SYM
admet-34	262	16	cm3	cm3	PROPN
admet-34	262	17	amorphous	amorphous	ADJ
admet-34	262	18	tem	tem	PROPN
admet-34	262	19	,	,	PUNCT
admet-34	262	20	0.14	0.14	NUM
admet-34	262	21	g	g	PROPN
admet-34	262	22	/	/	SYM
admet-34	262	23	cm3	cm3	PROPN
admet-34	262	24	,	,	PUNCT
admet-34	262	25	crystalline	crystalline	ADJ
admet-34	262	26	tem	tem	PROPN
admet-34	262	27	)	)	PUNCT
admet-34	262	28	but	but	CCONJ
admet-34	262	29	,	,	PUNCT
admet-34	262	30	also	also	ADV
admet-34	262	31	,	,	PUNCT
admet-34	262	32	maximum	maximum	ADJ
admet-34	262	33	cp	cp	PROPN
admet-34	262	34	occurs	occur	VERB
admet-34	262	35	after	after	ADP
admet-34	262	36	about	about	ADV
admet-34	262	37	2	2	NUM
admet-34	262	38	h	h	NOUN
admet-34	262	39	instead	instead	ADV
admet-34	262	40	of	of	ADP
admet-34	262	41	about	about	ADV
admet-34	262	42	3.5	3.5	NUM
admet-34	262	43	h	h	NOUN
admet-34	262	44	(	(	PUNCT
admet-34	262	45	crystalline	crystalline	PROPN
admet-34	262	46	tem	tem	PROPN
admet-34	262	47	)	)	PUNCT
admet-34	262	48	.	.	PUNCT
admet-34	263	1	this	this	DET
admet-34	263	2	simulation	simulation	NOUN
admet-34	263	3	was	be	AUX
admet-34	263	4	performed	perform	VERB
admet-34	263	5	assuming	assume	VERB
admet-34	263	6	that	that	SCONJ
admet-34	263	7	amorphous	amorphous	ADJ
admet-34	263	8	tem	tem	PROPN
admet-34	263	9	re	re	NOUN
admet-34	263	10	-	-	NOUN
admet-34	263	11	crystallisation	crystallisation	NOUN
admet-34	263	12	did	do	AUX
admet-34	263	13	not	not	PART
admet-34	263	14	occur	occur	VERB
admet-34	263	15	inside	inside	ADP
admet-34	263	16	the	the	DET
admet-34	263	17	stomach	stomach	NOUN
admet-34	263	18	although	although	SCONJ
admet-34	263	19	we	we	PRON
admet-34	263	20	have	have	VERB
admet-34	263	21	evidence	evidence	NOUN
admet-34	263	22	of	of	ADP
admet-34	263	23	the	the	DET
admet-34	263	24	contrary	contrary	NOUN
admet-34	263	25	in	in	ADP
admet-34	263	26	water	water	NOUN
admet-34	264	1	[	[	X
admet-34	264	2	11	11	NUM
admet-34	264	3	]	]	PUNCT
admet-34	264	4	.	.	PUNCT
admet-34	265	1	actually	actually	ADV
admet-34	265	2	,	,	PUNCT
admet-34	265	3	as	as	SCONJ
admet-34	265	4	re	re	NOUN
admet-34	265	5	-	-	NOUN
admet-34	265	6	crystallisation	crystallisation	ADJ
admet-34	265	7	kinetics	kinetic	NOUN
admet-34	265	8	can	can	AUX
admet-34	265	9	strongly	strongly	ADV
admet-34	265	10	depend	depend	VERB
admet-34	265	11	also	also	ADV
admet-34	265	12	on	on	ADP
admet-34	265	13	the	the	DET
admet-34	265	14	physical	physical	ADJ
admet-34	265	15	/	/	SYM
admet-34	265	16	chemical	chemical	NOUN
admet-34	265	17	properties	property	NOUN
admet-34	265	18	of	of	ADP
admet-34	265	19	the	the	DET
admet-34	265	20	dissolving	dissolving	NOUN
admet-34	265	21	fluids	fluid	NOUN
admet-34	265	22	(	(	PUNCT
admet-34	265	23	stomach	stomach	NOUN
admet-34	265	24	fluids	fluid	NOUN
admet-34	265	25	differ	differ	VERB
admet-34	265	26	a	a	DET
admet-34	265	27	lot	lot	NOUN
admet-34	265	28	from	from	ADP
admet-34	265	29	simple	simple	ADJ
admet-34	265	30	water	water	NOUN
admet-34	265	31	)	)	PUNCT
admet-34	265	32	,	,	PUNCT
admet-34	265	33	lacking	lack	VERB
admet-34	265	34	precise	precise	ADJ
admet-34	265	35	information	information	NOUN
admet-34	265	36	about	about	ADP
admet-34	265	37	tem	tem	PROPN
admet-34	265	38	re	re	NOUN
admet-34	265	39	-	-	NOUN
admet-34	265	40	crystallisation	crystallisation	NOUN
admet-34	265	41	in	in	ADP
admet-34	265	42	the	the	DET
admet-34	265	43	stomach	stomach	NOUN
admet-34	265	44	fluids	fluid	NOUN
admet-34	265	45	,	,	PUNCT
admet-34	265	46	induced	induce	VERB
admet-34	265	47	us	we	PRON
admet-34	265	48	to	to	PART
admet-34	265	49	assume	assume	VERB
admet-34	265	50	that	that	SCONJ
admet-34	265	51	re	re	NOUN
admet-34	265	52	-	-	NOUN
admet-34	265	53	crystallisation	crystallisation	NOUN
admet-34	265	54	did	do	AUX
admet-34	265	55	not	not	PART
admet-34	265	56	occur	occur	VERB
admet-34	265	57	.	.	PUNCT
admet-34	266	1	in	in	ADP
admet-34	266	2	so	so	ADV
admet-34	266	3	doing	do	VERB
admet-34	266	4	,	,	PUNCT
admet-34	266	5	we	we	PRON
admet-34	266	6	estimated	estimate	VERB
admet-34	266	7	the	the	DET
admet-34	266	8	maximum	maximum	ADJ
admet-34	266	9	possible	possible	ADJ
admet-34	266	10	effect	effect	NOUN
admet-34	266	11	of	of	ADP
admet-34	266	12	amorphous	amorphous	ADJ
admet-34	266	13	tem	tem	PROPN
admet-34	266	14	over	over	ADP
admet-34	266	15	the	the	DET
admet-34	266	16	native	native	ADJ
admet-34	266	17	crystalline	crystalline	PROPN
admet-34	266	18	tem	tem	PROPN
admet-34	266	19	.	.	PUNCT
admet-34	267	1	figure	figure	NOUN
admet-34	267	2	3b	3b	PROPN
admet-34	267	3	shows	show	VERB
admet-34	267	4	that	that	SCONJ
admet-34	267	5	,	,	PUNCT
admet-34	267	6	in	in	ADP
admet-34	267	7	the	the	DET
admet-34	267	8	amorphous	amorphous	ADJ
admet-34	267	9	case	case	NOUN
admet-34	267	10	,	,	PUNCT
admet-34	267	11	drug	drug	NOUN
admet-34	267	12	del	del	PROPN
admet-34	267	13	cont	cont	PROPN
admet-34	267	14	et	et	PROPN
admet-34	267	15	al	al	PROPN
admet-34	267	16	.	.	PROPN
admet-34	267	17	admet	admet	PROPN
admet-34	267	18	&	&	CCONJ
admet-34	267	19	dmpk	dmpk	PROPN
admet-34	267	20	2(2	2(2	NUM
admet-34	267	21	)	)	PUNCT
admet-34	267	22	(	(	PUNCT
admet-34	267	23	2014	2014	NUM
admet-34	267	24	)	)	PUNCT
admet-34	267	25	80	80	NUM
admet-34	267	26	-	-	SYM
admet-34	267	27	97	97	NUM
admet-34	267	28	90	90	NUM
admet-34	267	29	concentration	concentration	NOUN
admet-34	267	30	(	(	PUNCT
admet-34	267	31	cr	cr	NOUN
admet-34	267	32	)	)	PUNCT
admet-34	267	33	rapidly	rapidly	ADV
admet-34	267	34	reaches	reach	VERB
admet-34	267	35	the	the	DET
admet-34	267	36	maximum	maximum	ADJ
admet-34	267	37	admissible	admissible	ADJ
admet-34	267	38	concentration	concentration	NOUN
admet-34	267	39	(	(	PUNCT
admet-34	267	40	400	400	NUM
admet-34	267	41	g	g	NOUN
admet-34	267	42	/	/	SYM
admet-34	267	43	cm	cm	NOUN
admet-34	267	44	3	3	NUM
admet-34	267	45	)	)	PUNCT
admet-34	267	46	compatible	compatible	ADJ
admet-34	267	47	with	with	ADP
admet-34	267	48	the	the	DET
admet-34	267	49	administered	administer	VERB
admet-34	267	50	dose	dose	NOUN
admet-34	267	51	(	(	PUNCT
admet-34	267	52	100	100	NUM
admet-34	267	53	mg	mg	NUM
admet-34	267	54	)	)	PUNCT
admet-34	267	55	.	.	PUNCT
admet-34	268	1	this	this	PRON
admet-34	268	2	,	,	PUNCT
admet-34	268	3	obviously	obviously	ADV
admet-34	268	4	,	,	PUNCT
admet-34	268	5	takes	take	VERB
admet-34	268	6	place	place	NOUN
admet-34	268	7	in	in	ADP
admet-34	268	8	the	the	DET
admet-34	268	9	stomach	stomach	NOUN
admet-34	268	10	(	(	PUNCT
admet-34	268	11	t	t	X
admet-34	268	12	<	<	X
admet-34	268	13	0.8	0.8	NUM
admet-34	268	14	h	h	NOUN
admet-34	268	15	)	)	PUNCT
admet-34	268	16	while	while	SCONJ
admet-34	268	17	,	,	PUNCT
admet-34	268	18	once	once	ADV
admet-34	268	19	in	in	ADP
admet-34	268	20	the	the	DET
admet-34	268	21	sil	sil	PROPN
admet-34	268	22	and	and	CCONJ
admet-34	268	23	,	,	PUNCT
admet-34	268	24	eventually	eventually	ADV
admet-34	268	25	,	,	PUNCT
admet-34	268	26	in	in	ADP
admet-34	268	27	the	the	DET
admet-34	268	28	lil	lil	NOUN
admet-34	268	29	,	,	PUNCT
admet-34	268	30	cr	cr	NOUN
admet-34	268	31	decreases	decrease	VERB
admet-34	268	32	up	up	ADP
admet-34	268	33	to	to	ADP
admet-34	268	34	disappearing	disappear	VERB
admet-34	268	35	.	.	PUNCT
admet-34	269	1	in	in	ADP
admet-34	269	2	the	the	DET
admet-34	269	3	crystalline	crystalline	NOUN
admet-34	269	4	case	case	NOUN
admet-34	269	5	,	,	PUNCT
admet-34	269	6	on	on	ADP
admet-34	269	7	the	the	DET
admet-34	269	8	contrary	contrary	NOUN
admet-34	269	9	,	,	PUNCT
admet-34	269	10	cr	cr	PROPN
admet-34	269	11	increase	increase	NOUN
admet-34	269	12	is	be	AUX
admet-34	269	13	smaller	small	ADJ
admet-34	269	14	and	and	CCONJ
admet-34	269	15	the	the	DET
admet-34	269	16	maximum	maximum	ADJ
admet-34	269	17	value	value	NOUN
admet-34	269	18	is	be	AUX
admet-34	269	19	well	well	ADV
admet-34	269	20	below	below	ADP
admet-34	269	21	that	that	PRON
admet-34	269	22	reached	reach	VERB
admet-34	269	23	in	in	ADP
admet-34	269	24	the	the	DET
admet-34	269	25	amorphous	amorphous	ADJ
admet-34	269	26	case	case	NOUN
admet-34	269	27	.	.	PUNCT
admet-34	270	1	table	table	NOUN
admet-34	270	2	2	2	NUM
admet-34	270	3	.	.	PUNCT
admet-34	270	4	model	model	NOUN
admet-34	270	5	parameters	parameter	NOUN
admet-34	270	6	referring	refer	VERB
admet-34	270	7	to	to	ADP
admet-34	270	8	temazepam	temazepam	NOUN
admet-34	270	9	(	(	PUNCT
admet-34	270	10	release	release	NOUN
admet-34	270	11	environment	environment	NOUN
admet-34	270	12	vr	vr	NOUN
admet-34	270	13	=	=	NOUN
admet-34	270	14	250	250	NUM
admet-34	270	15	cm	cm	NUM
admet-34	270	16	3	3	NUM
admet-34	270	17	,	,	PUNCT
admet-34	270	18	polymeric	polymeric	ADJ
admet-34	270	19	carrier	carrier	NOUN
admet-34	270	20	density	density	NOUN
admet-34	270	21	1.2	1.2	NUM
admet-34	270	22	g	g	NOUN
admet-34	270	23	/	/	SYM
admet-34	270	24	cm	cm	NOUN
admet-34	270	25	3	3	NUM
admet-34	270	26	)	)	PUNCT
admet-34	270	27	pk	pk	NOUN
admet-34	270	28	parameters	parameter	NOUN
admet-34	270	29	[	[	X
admet-34	270	30	10	10	NUM
admet-34	270	31	]	]	SYM
admet-34	270	32	vp(cm3	vp(cm3	NUM
admet-34	270	33	)	)	PUNCT
admet-34	270	34	vl(cm3	vl(cm3	NOUN
admet-34	270	35	)	)	PUNCT
admet-34	270	36	vgics(cm3	vgics(cm3	NOUN
admet-34	270	37	)	)	PUNCT
admet-34	270	38	vt(cm3	vt(cm3	NUM
admet-34	270	39	)	)	PUNCT
admet-34	270	40	229000	229000	NUM
admet-34	270	41	1500	1500	NUM
admet-34	270	42	9.96	9.96	NUM
admet-34	270	43	152000	152000	NUM
admet-34	270	44	qpv(cm3	qpv(cm3	PROPN
admet-34	270	45	/	/	SYM
admet-34	270	46	s	s	PART
admet-34	270	47	)	)	PUNCT
admet-34	270	48	qha(cm3	qha(cm3	PROPN
admet-34	270	49	/	/	SYM
admet-34	270	50	s	s	PART
admet-34	270	51	)	)	PUNCT
admet-34	270	52	qhv(cm3	qhv(cm3	PROPN
admet-34	270	53	/	/	SYM
admet-34	270	54	s	s	PART
admet-34	270	55	)	)	PUNCT
admet-34	270	56	clh(cm3	clh(cm3	PROPN
admet-34	270	57	/	/	SYM
admet-34	270	58	s	s	NOUN
admet-34	270	59	)	)	PUNCT
admet-34	270	60	16.25	16.25	NUM
admet-34	270	61	5.41	5.41	NUM
admet-34	270	62	21.6	21.6	NUM
admet-34	270	63	16.46	16.46	NUM
admet-34	270	64	re	re	NOUN
admet-34	270	65	elk	elk	PROPN
admet-34	270	66	(	(	PUNCT
admet-34	270	67	1	1	NUM
admet-34	270	68	/	/	SYM
admet-34	270	69	s	s	NOUN
admet-34	270	70	)	)	PUNCT
admet-34	270	71	kel(1	kel(1	NOUN
admet-34	270	72	/	/	SYM
admet-34	270	73	s	s	NOUN
admet-34	270	74	)	)	PUNCT
admet-34	270	75	ktp(1	ktp(1	NOUN
admet-34	270	76	/	/	SYM
admet-34	270	77	s	s	NOUN
admet-34	270	78	)	)	PUNCT
admet-34	270	79	ktp(1	ktp(1	NOUN
admet-34	270	80	/	/	SYM
admet-34	270	81	s	s	PROPN
admet-34	270	82	)	)	PUNCT
admet-34	270	83	0.0	0.0	NUM
admet-34	270	84	0.0	0.0	NUM
admet-34	270	85	6.4	6.4	NUM
admet-34	270	86	*	*	SYM
admet-34	270	87	10	10	NUM
admet-34	270	88	-	-	SYM
admet-34	270	89	5	5	NUM
admet-34	270	90	10	10	NUM
admet-34	270	91	-	-	SYM
admet-34	270	92	6	6	NUM
admet-34	270	93	tgl(s	tgl(s	NOUN
admet-34	270	94	)	)	PUNCT
admet-34	270	95	rgl(cm	rgl(cm	NOUN
admet-34	270	96	)	)	PUNCT
admet-34	271	1	i	i	PRON
admet-34	271	2	glr	glr	PROPN
admet-34	271	3	(	(	PUNCT
admet-34	271	4	cm	cm	NOUN
admet-34	271	5	)	)	PUNCT
admet-34	271	6	pgl(cm	pgl(cm	NOUN
admet-34	271	7	/	/	SYM
admet-34	271	8	s	s	NOUN
admet-34	271	9	)	)	PUNCT
admet-34	271	10	2880	2880	NUM
admet-34	271	11	7.5	7.5	NUM
admet-34	271	12	0.0	0.0	NUM
admet-34	271	13	0.0	0.0	NUM
admet-34	271	14	tsil(s	tsil(s	NOUN
admet-34	271	15	)	)	PUNCT
admet-34	271	16	rsil(cm	rsil(cm	NOUN
admet-34	271	17	)	)	PUNCT
admet-34	272	1	i	i	PRON
admet-34	272	2	silr	silr	NOUN
admet-34	272	3	(	(	PUNCT
admet-34	272	4	cm	cm	NOUN
admet-34	272	5	)	)	PUNCT
admet-34	272	6	psil(cm	psil(cm	NOUN
admet-34	272	7	/	/	SYM
admet-34	272	8	s	s	NOUN
admet-34	272	9	)	)	PUNCT
admet-34	272	10	11520.0	11520.0	NUM
admet-34	272	11	2.5	2.5	NUM
admet-34	272	12	0.0	0.0	NUM
admet-34	272	13	6.0	6.0	NUM
admet-34	272	14	*	*	NUM
admet-34	272	15	10	10	NUM
admet-34	272	16	-	-	SYM
admet-34	272	17	4	4	NUM
admet-34	272	18	til(s	til(s	NOUN
admet-34	272	19	)	)	PUNCT
admet-34	272	20	rlil(cm	rlil(cm	NOUN
admet-34	272	21	)	)	PUNCT
admet-34	273	1	i	i	PRON
admet-34	273	2	lilr	lilr	VERB
admet-34	273	3	(	(	PUNCT
admet-34	273	4	cm	cm	NOUN
admet-34	273	5	)	)	PUNCT
admet-34	273	6	plil(cm	plil(cm	NOUN
admet-34	273	7	/	/	SYM
admet-34	273	8	s	s	PROPN
admet-34	273	9	)	)	PUNCT
admet-34	273	10	115200.0	115200.0	NUM
admet-34	273	11	2.5	2.5	NUM
admet-34	273	12	0.0	0.0	NUM
admet-34	273	13	3.0	3.0	NUM
admet-34	273	14	*	*	SYM
admet-34	273	15	10	10	NUM
admet-34	273	16	-	-	SYM
admet-34	273	17	4	4	NUM
admet-34	273	18	delivery	delivery	NOUN
admet-34	273	19	parameters	parameter	NOUN
admet-34	274	1	[	[	X
admet-34	274	2	11	11	NUM
admet-34	274	3	]	]	X
admet-34	274	4	ceq(g	ceq(g	PROPN
admet-34	274	5	/	/	SYM
admet-34	274	6	cm3	cm3	PROPN
admet-34	274	7	)	)	PUNCT
admet-34	274	8	eq(s	eq(s	NOUN
admet-34	274	9	)	)	PUNCT
admet-34	274	10	deq(cm2	deq(cm2	PROPN
admet-34	274	11	/	/	SYM
admet-34	274	12	s	s	NOUN
admet-34	274	13	)	)	PUNCT
admet-34	274	14	d0(cm2	d0(cm2	PROPN
admet-34	274	15	/	/	SYM
admet-34	274	16	s	s	PROPN
admet-34	274	17	)	)	PUNCT
admet-34	274	18	0.31	0.31	NUM
admet-34	274	19	0.35	0.35	NUM
admet-34	274	20	10	10	NUM
admet-34	274	21	-	-	SYM
admet-34	274	22	7	7	NUM
admet-34	274	23	10	10	NUM
admet-34	274	24	-	-	SYM
admet-34	274	25	10	10	NUM
admet-34	274	26	g(cm3	g(cm3	PROPN
admet-34	274	27	/	/	SYM
admet-34	274	28	g	g	NOUN
admet-34	274	29	)	)	PUNCT
admet-34	274	30	f(cm3	f(cm3	NOUN
admet-34	274	31	/	/	SYM
admet-34	274	32	g	g	NOUN
admet-34	274	33	)	)	PUNCT
admet-34	274	34	dds(cm2	dds(cm2	PROPN
admet-34	274	35	/	/	SYM
admet-34	274	36	s	s	NOUN
admet-34	274	37	)	)	PUNCT
admet-34	274	38	kp(-	kp(-	PROPN
admet-34	274	39	)	)	PUNCT
admet-34	274	40	52.0	52.0	NUM
admet-34	274	41	12.0	12.0	NUM
admet-34	274	42	7.2	7.2	NUM
admet-34	274	43	*	*	NUM
admet-34	274	44	10	10	NUM
admet-34	274	45	-	-	SYM
admet-34	274	46	6	6	NUM
admet-34	274	47	1.0	1.0	NUM
admet-34	274	48	mc	mc	PROPN
admet-34	274	49	sc	sc	PROPN
admet-34	274	50	(	(	PUNCT
admet-34	274	51	g	g	PROPN
admet-34	274	52	/	/	SYM
admet-34	274	53	cm3	cm3	PROPN
admet-34	274	54	)	)	PUNCT
admet-34	274	55	k(1	k(1	PROPN
admet-34	274	56	/	/	SYM
admet-34	274	57	s	s	PROPN
admet-34	274	58	)	)	PUNCT
admet-34	274	59	kr(1	kr(1	PROPN
admet-34	274	60	/	/	SYM
admet-34	274	61	s	s	NOUN
admet-34	274	62	)	)	PUNCT
admet-34	274	63	krb(1	krb(1	PROPN
admet-34	274	64	/	/	SYM
admet-34	274	65	s	s	PROPN
admet-34	274	66	)	)	PUNCT
admet-34	274	67	164	164	NUM
admet-34	274	68	0.1	0.1	NUM
admet-34	274	69	0.007	0.007	NUM
admet-34	274	70	0.0	0.0	NUM
admet-34	274	71	nc	nc	PROPN
admet-34	274	72	sc	sc	PROPN
admet-34	274	73	(	(	PUNCT
admet-34	274	74	g	g	PROPN
admet-34	274	75	/	/	SYM
admet-34	274	76	cm3	cm3	PROPN
admet-34	274	77	)	)	PUNCT
admet-34	274	78	am	be	AUX
admet-34	274	79	sc	sc	PROPN
admet-34	274	80	(	(	PUNCT
admet-34	274	81	g	g	PROPN
admet-34	274	82	/	/	SYM
admet-34	274	83	cm3	cm3	NOUN
admet-34	274	84	)	)	PUNCT
admet-34	274	85	224	224	NUM
admet-34	274	86	8649	8649	NUM
admet-34	274	87	at	at	ADP
admet-34	274	88	the	the	DET
admet-34	274	89	same	same	ADJ
admet-34	274	90	time	time	NOUN
admet-34	274	91	,	,	PUNCT
admet-34	274	92	cr	cr	PROPN
admet-34	274	93	reduction	reduction	NOUN
admet-34	274	94	in	in	ADP
admet-34	274	95	the	the	DET
admet-34	274	96	sil	sil	PROPN
admet-34	274	97	and	and	CCONJ
admet-34	274	98	in	in	ADP
admet-34	274	99	the	the	DET
admet-34	274	100	lil	lil	NOUN
admet-34	274	101	is	be	AUX
admet-34	274	102	slower	slow	ADJ
admet-34	274	103	thus	thus	ADV
admet-34	274	104	ensuring	ensure	VERB
admet-34	274	105	higher	high	ADJ
admet-34	274	106	cp	cp	NOUN
admet-34	274	107	from	from	ADP
admet-34	274	108	4	4	NUM
admet-34	274	109	hours	hour	NOUN
admet-34	274	110	onwards	onwards	ADV
admet-34	274	111	.	.	PUNCT
admet-34	275	1	in	in	ADP
admet-34	275	2	the	the	DET
admet-34	275	3	case	case	NOUN
admet-34	275	4	of	of	ADP
admet-34	275	5	a	a	DET
admet-34	275	6	system	system	NOUN
admet-34	275	7	characterised	characterise	VERB
admet-34	275	8	by	by	ADP
admet-34	275	9	50	50	NUM
admet-34	275	10	%	%	NOUN
admet-34	275	11	amorphous	amorphous	ADJ
admet-34	275	12	tem	tem	NOUN
admet-34	275	13	and	and	CCONJ
admet-34	275	14	50	50	NUM
admet-34	275	15	%	%	NOUN
admet-34	275	16	crystalline	crystalline	PROPN
admet-34	275	17	tem	tem	PROPN
admet-34	275	18	,	,	PUNCT
admet-34	275	19	both	both	CCONJ
admet-34	275	20	the	the	DET
admet-34	275	21	cp	cp	NOUN
admet-34	275	22	and	and	CCONJ
admet-34	275	23	the	the	DET
admet-34	275	24	cr	cr	PROPN
admet-34	275	25	trends	trend	NOUN
admet-34	275	26	are	be	AUX
admet-34	275	27	,	,	PUNCT
admet-34	275	28	more	more	ADV
admet-34	275	29	or	or	CCONJ
admet-34	275	30	less	less	ADJ
admet-34	275	31	,	,	PUNCT
admet-34	275	32	in	in	ADP
admet-34	275	33	between	between	ADP
admet-34	275	34	those	those	PRON
admet-34	275	35	competing	compete	VERB
admet-34	275	36	to	to	ADP
admet-34	275	37	the	the	DET
admet-34	275	38	completely	completely	ADV
admet-34	275	39	amorphous	amorphous	ADJ
admet-34	275	40	and	and	CCONJ
admet-34	275	41	the	the	DET
admet-34	275	42	totally	totally	ADV
admet-34	275	43	crystalline	crystalline	ADJ
admet-34	275	44	tem	tem	PROPN
admet-34	275	45	as	as	SCONJ
admet-34	275	46	depicted	depict	VERB
admet-34	275	47	by	by	ADP
admet-34	275	48	the	the	DET
admet-34	275	49	grey	grey	PROPN
admet-34	275	50	lines	line	NOUN
admet-34	275	51	in	in	ADP
admet-34	275	52	figure	figure	NOUN
admet-34	275	53	3a	3a	NUM
admet-34	275	54	and	and	CCONJ
admet-34	275	55	3b	3b	NUM
admet-34	275	56	.	.	PUNCT
admet-34	276	1	finally	finally	ADV
admet-34	276	2	,	,	PUNCT
admet-34	276	3	it	it	PRON
admet-34	276	4	is	be	AUX
admet-34	276	5	interesting	interesting	ADJ
admet-34	276	6	to	to	PART
admet-34	276	7	notice	notice	VERB
admet-34	276	8	that	that	SCONJ
admet-34	276	9	cr	cr	PROPN
admet-34	276	10	fastest	fast	ADJ
admet-34	276	11	variations	variation	NOUN
admet-34	276	12	occur	occur	VERB
admet-34	276	13	when	when	SCONJ
admet-34	276	14	the	the	DET
admet-34	276	15	delivery	delivery	NOUN
admet-34	276	16	system	system	NOUN
admet-34	276	17	leaves	leave	VERB
admet-34	276	18	the	the	DET
admet-34	276	19	stomach	stomach	NOUN
admet-34	276	20	(	(	PUNCT
admet-34	276	21	0.8	0.8	NUM
admet-34	276	22	h	h	NOUN
admet-34	276	23	)	)	PUNCT
admet-34	276	24	and	and	CCONJ
admet-34	276	25	the	the	DET
admet-34	276	26	lil	lil	NOUN
admet-34	276	27	(	(	PUNCT
admet-34	276	28	3.2	3.2	NUM
admet-34	276	29	h	h	NOUN
admet-34	276	30	)	)	PUNCT
admet-34	276	31	(	(	PUNCT
admet-34	276	32	figure	figure	NOUN
admet-34	276	33	3b	3b	NUM
admet-34	276	34	)	)	PUNCT
admet-34	276	35	and	and	CCONJ
admet-34	276	36	this	this	PRON
admet-34	276	37	is	be	AUX
admet-34	276	38	determined	determine	VERB
admet-34	276	39	by	by	ADP
admet-34	276	40	the	the	DET
admet-34	276	41	gi	gi	PROPN
admet-34	276	42	tract	tract	NOUN
admet-34	276	43	permeability	permeability	NOUN
admet-34	276	44	variation	variation	NOUN
admet-34	276	45	.	.	PUNCT
admet-34	277	1	the	the	DET
admet-34	277	2	last	last	ADJ
admet-34	277	3	drug	drug	NOUN
admet-34	277	4	considered	consider	VERB
admet-34	277	5	is	be	AUX
admet-34	277	6	nimesulide	nimesulide	ADJ
admet-34	277	7	,	,	PUNCT
admet-34	277	8	a	a	DET
admet-34	277	9	typical	typical	ADJ
admet-34	277	10	non	non	ADJ
admet-34	277	11	-	-	ADJ
admet-34	277	12	steroidal	steroidal	ADJ
admet-34	277	13	anti	anti	ADJ
admet-34	277	14	-	-	ADJ
admet-34	277	15	inflammatory	inflammatory	ADJ
admet-34	277	16	drug	drug	NOUN
admet-34	277	17	that	that	PRON
admet-34	277	18	has	have	AUX
admet-34	277	19	been	be	AUX
admet-34	277	20	largely	largely	ADV
admet-34	277	21	employed	employ	VERB
admet-34	277	22	in	in	ADP
admet-34	277	23	clinical	clinical	ADJ
admet-34	277	24	practice	practice	NOUN
admet-34	277	25	[	[	X
admet-34	277	26	30	30	NUM
admet-34	277	27	]	]	PUNCT
admet-34	277	28	.	.	PUNCT
admet-34	278	1	like	like	INTJ
admet-34	278	2	tem	tem	PROPN
admet-34	278	3	,	,	PUNCT
admet-34	278	4	it	it	PRON
admet-34	278	5	is	be	AUX
admet-34	278	6	scarcely	scarcely	ADV
admet-34	278	7	soluble	soluble	ADJ
admet-34	278	8	in	in	ADP
admet-34	278	9	aqueous	aqueous	ADJ
admet-34	278	10	media	medium	NOUN
admet-34	278	11	but	but	CCONJ
admet-34	278	12	its	its	PRON
admet-34	278	13	solubility	solubility	NOUN
admet-34	278	14	is	be	AUX
admet-34	278	15	ph	ph	ADV
admet-34	278	16	dependent	dependent	ADJ
admet-34	278	17	as	as	SCONJ
admet-34	278	18	it	it	PRON
admet-34	278	19	is	be	AUX
admet-34	278	20	a	a	DET
admet-34	278	21	weak	weak	ADJ
admet-34	278	22	acid	acid	NOUN
admet-34	278	23	(	(	PUNCT
admet-34	279	1	pka	pka	NOUN
admet-34	279	2	=	=	PUNCT
admet-34	279	3	6.46	6.46	NUM
admet-34	280	1	[	[	X
admet-34	280	2	31	31	NUM
admet-34	280	3	]	]	PUNCT
admet-34	280	4	)	)	PUNCT
admet-34	280	5	.	.	PUNCT
admet-34	281	1	thus	thus	ADV
admet-34	281	2	,	,	PUNCT
admet-34	281	3	water	water	NOUN
admet-34	281	4	solubility	solubility	NOUN
admet-34	281	5	at	at	ADP
admet-34	281	6	37	37	NUM
admet-34	281	7	°	°	SYM
admet-34	281	8	c	c	NOUN
admet-34	281	9	is	be	AUX
admet-34	281	10	around	around	ADV
admet-34	281	11	10	10	NUM
admet-34	281	12	g	g	NOUN
admet-34	281	13	/	/	SYM
admet-34	281	14	cm3	cm3	NOUN
admet-34	281	15	for	for	ADP
admet-34	281	16	ph	ph	NOUN
admet-34	281	17	<	<	X
admet-34	281	18	pka	pka	PROPN
admet-34	281	19	,	,	PUNCT
admet-34	281	20	while	while	SCONJ
admet-34	281	21	solubility	solubility	NOUN
admet-34	281	22	increases	increase	VERB
admet-34	281	23	to	to	ADP
admet-34	281	24	about	about	ADV
admet-34	281	25	100	100	NUM
admet-34	281	26	g	g	NOUN
admet-34	281	27	/	/	SYM
admet-34	281	28	cm3	cm3	NOUN
admet-34	281	29	with	with	ADP
admet-34	281	30	higher	high	ADJ
admet-34	281	31	ph	ph	NOUN
admet-34	282	1	[	[	X
admet-34	282	2	32	32	NUM
admet-34	282	3	]	]	PUNCT
admet-34	282	4	.	.	PUNCT
admet-34	283	1	obviously	obviously	ADV
admet-34	283	2	,	,	PUNCT
admet-34	283	3	nimesulide	nimesulide	ADP
admet-34	283	4	solubility	solubility	NOUN
admet-34	283	5	can	can	AUX
admet-34	283	6	be	be	AUX
admet-34	283	7	improved	improve	VERB
admet-34	283	8	by	by	ADP
admet-34	283	9	using	use	VERB
admet-34	283	10	it	it	PRON
admet-34	283	11	in	in	ADP
admet-34	283	12	its	its	PRON
admet-34	283	13	amorphous	amorphous	ADJ
admet-34	283	14	/	/	SYM
admet-34	283	15	nano	nano	NOUN
admet-34	283	16	-	-	PUNCT
admet-34	283	17	crystalline	crystalline	NOUN
admet-34	283	18	state	state	NOUN
admet-34	283	19	[	[	X
admet-34	283	20	19	19	NUM
admet-34	283	21	]	]	PUNCT
admet-34	283	22	.	.	PUNCT
admet-34	284	1	in	in	ADP
admet-34	284	2	addition	addition	NOUN
admet-34	284	3	,	,	PUNCT
admet-34	284	4	the	the	DET
admet-34	284	5	firstpass	firstpass	ADJ
admet-34	284	6	liver	liver	NOUN
admet-34	284	7	effect	effect	NOUN
admet-34	284	8	for	for	ADP
admet-34	284	9	nimesulide	nimesulide	NOUN
admet-34	284	10	is	be	AUX
admet-34	284	11	negligible	negligible	ADJ
admet-34	284	12	[	[	X
admet-34	284	13	30	30	NUM
admet-34	284	14	]	]	PUNCT
admet-34	284	15	.	.	PUNCT
admet-34	285	1	admet	admet	PROPN
admet-34	285	2	&	&	CCONJ
admet-34	285	3	dmpk	dmpk	PROPN
admet-34	285	4	2(2	2(2	NUM
admet-34	285	5	)	)	PUNCT
admet-34	285	6	(	(	PUNCT
admet-34	285	7	2014	2014	NUM
admet-34	285	8	)	)	PUNCT
admet-34	285	9	80	80	NUM
admet-34	285	10	-	-	SYM
admet-34	285	11	97	97	NUM
admet-34	285	12	in	in	ADP
admet-34	285	13	vivo	vivo	ADJ
admet-34	285	14	drug	drug	NOUN
admet-34	285	15	release	release	NOUN
admet-34	285	16	and	and	CCONJ
admet-34	285	17	absorption	absorption	NOUN
admet-34	285	18	doi	doi	NOUN
admet-34	285	19	:	:	PUNCT
admet-34	285	20	10.5599	10.5599	NUM
admet-34	285	21	/	/	SYM
admet-34	285	22	admet.2.2.34	admet.2.2.34	PROPN
admet-34	285	23	91	91	NUM
admet-34	285	24	figure	figure	NOUN
admet-34	285	25	3	3	NUM
admet-34	285	26	.	.	PUNCT
admet-34	286	1	(	(	PUNCT
admet-34	286	2	a	a	X
admet-34	286	3	)	)	PUNCT
admet-34	286	4	temazepam	temazepam	NOUN
admet-34	286	5	plasma	plasma	NOUN
admet-34	286	6	concentration	concentration	NOUN
admet-34	286	7	cp	cp	INTJ
admet-34	286	8	referring	refer	VERB
admet-34	286	9	to	to	ADP
admet-34	286	10	amorphous	amorphous	ADJ
admet-34	286	11	(	(	PUNCT
admet-34	286	12	thick	thick	ADJ
admet-34	286	13	black	black	ADJ
admet-34	286	14	line	line	NOUN
admet-34	286	15	)	)	PUNCT
admet-34	286	16	and	and	CCONJ
admet-34	286	17	crystalline	crystalline	NOUN
admet-34	286	18	(	(	PUNCT
admet-34	286	19	thin	thin	ADJ
admet-34	286	20	black	black	ADJ
admet-34	286	21	line	line	NOUN
admet-34	286	22	)	)	PUNCT
admet-34	286	23	drug	drug	NOUN
admet-34	286	24	.	.	PUNCT
admet-34	287	1	the	the	DET
admet-34	287	2	gray	gray	ADJ
admet-34	287	3	line	line	NOUN
admet-34	287	4	refers	refer	VERB
admet-34	287	5	to	to	ADP
admet-34	287	6	a	a	DET
admet-34	287	7	system	system	NOUN
admet-34	287	8	containing	contain	VERB
admet-34	287	9	50	50	NUM
admet-34	287	10	%	%	NOUN
admet-34	287	11	amorphous	amorphous	ADJ
admet-34	287	12	and	and	CCONJ
admet-34	287	13	50	50	NUM
admet-34	287	14	%	%	NOUN
admet-34	287	15	crystalline	crystalline	NOUN
admet-34	287	16	temazepam	temazepam	NOUN
admet-34	287	17	.	.	PUNCT
admet-34	288	1	delivery	delivery	NOUN
admet-34	288	2	systems	system	NOUN
admet-34	288	3	volume	volume	NOUN
admet-34	288	4	is	be	AUX
admet-34	288	5	equal	equal	ADJ
admet-34	288	6	to	to	ADP
admet-34	288	7	1	1	NUM
admet-34	288	8	cm	cm	NUM
admet-34	288	9	3	3	NUM
admet-34	288	10	and	and	CCONJ
admet-34	288	11	dose	dose	NOUN
admet-34	288	12	is	be	AUX
admet-34	288	13	equal	equal	ADJ
admet-34	288	14	to	to	ADP
admet-34	288	15	100	100	NUM
admet-34	288	16	mg	mg	NOUN
admet-34	288	17	.	.	PUNCT
admet-34	289	1	(	(	PUNCT
admet-34	289	2	b	b	X
admet-34	289	3	)	)	PUNCT
admet-34	289	4	temazepam	temazepam	NOUN
admet-34	289	5	concentration	concentration	NOUN
admet-34	289	6	in	in	ADP
admet-34	289	7	the	the	DET
admet-34	289	8	release	release	NOUN
admet-34	289	9	environment	environment	NOUN
admet-34	289	10	(	(	PUNCT
admet-34	289	11	cr	cr	NOUN
admet-34	289	12	)	)	PUNCT
admet-34	289	13	referring	refer	VERB
admet-34	289	14	to	to	ADP
admet-34	289	15	the	the	DET
admet-34	289	16	three	three	NUM
admet-34	289	17	delivery	delivery	NOUN
admet-34	289	18	systems	system	NOUN
admet-34	289	19	shown	show	VERB
admet-34	289	20	in	in	ADP
admet-34	289	21	(	(	PUNCT
admet-34	289	22	a	a	NOUN
admet-34	289	23	)	)	PUNCT
admet-34	289	24	.	.	PUNCT
admet-34	290	1	the	the	DET
admet-34	290	2	numerical	numerical	ADJ
admet-34	290	3	solution	solution	NOUN
admet-34	290	4	of	of	ADP
admet-34	290	5	the	the	DET
admet-34	290	6	model	model	NOUN
admet-34	290	7	implied	imply	VERB
admet-34	290	8	the	the	DET
admet-34	290	9	subdivision	subdivision	NOUN
admet-34	290	10	of	of	ADP
admet-34	290	11	the	the	DET
admet-34	290	12	particles	particle	NOUN
admet-34	290	13	size	size	NOUN
admet-34	290	14	distribution	distribution	NOUN
admet-34	290	15	in	in	ADP
admet-34	290	16	10	10	NUM
admet-34	290	17	classes	class	NOUN
admet-34	290	18	and	and	CCONJ
admet-34	290	19	15	15	NUM
admet-34	290	20	control	control	NOUN
admet-34	290	21	volumes	volume	NOUN
admet-34	290	22	were	be	AUX
admet-34	290	23	considered	consider	VERB
admet-34	290	24	for	for	ADP
admet-34	290	25	the	the	DET
admet-34	290	26	generic	generic	ADJ
admet-34	290	27	particle	particle	NOUN
admet-34	290	28	of	of	ADP
admet-34	290	29	each	each	DET
admet-34	290	30	class	class	NOUN
admet-34	290	31	.	.	PUNCT
admet-34	291	1	while	while	SCONJ
admet-34	291	2	some	some	DET
admet-34	291	3	pk	pk	NOUN
admet-34	291	4	parameters	parameter	NOUN
admet-34	291	5	[	[	X
admet-34	291	6	10,16,30	10,16,30	X
admet-34	291	7	]	]	X
admet-34	291	8	and	and	CCONJ
admet-34	291	9	all	all	DET
admet-34	291	10	the	the	DET
admet-34	291	11	delivery	delivery	NOUN
admet-34	291	12	parameters	parameter	NOUN
admet-34	291	13	[	[	X
admet-34	291	14	11,19	11,19	X
admet-34	291	15	]	]	PUNCT
admet-34	291	16	can	can	AUX
admet-34	291	17	be	be	AUX
admet-34	291	18	deduced	deduce	VERB
admet-34	291	19	from	from	ADP
admet-34	291	20	literature	literature	NOUN
admet-34	291	21	,	,	PUNCT
admet-34	291	22	we	we	PRON
admet-34	291	23	could	could	AUX
admet-34	291	24	not	not	PART
admet-34	291	25	find	find	VERB
admet-34	291	26	reliable	reliable	ADJ
admet-34	291	27	estimation	estimation	NOUN
admet-34	291	28	of	of	ADP
admet-34	291	29	its	its	PRON
admet-34	291	30	solubility	solubility	NOUN
admet-34	291	31	in	in	ADP
admet-34	291	32	the	the	DET
admet-34	291	33	gastric	gastric	ADJ
admet-34	291	34	environment	environment	NOUN
admet-34	291	35	and	and	CCONJ
admet-34	291	36	its	its	PRON
admet-34	291	37	permeability	permeability	NOUN
admet-34	291	38	through	through	ADP
admet-34	291	39	the	the	DET
admet-34	291	40	gl	gl	PROPN
admet-34	291	41	,	,	PUNCT
admet-34	291	42	sil	sil	PROPN
admet-34	291	43	and	and	CCONJ
admet-34	291	44	lil	lil	VERB
admet-34	291	45	mucosa	mucosa	NOUN
admet-34	291	46	.	.	PUNCT
admet-34	292	1	thus	thus	ADV
admet-34	292	2	,	,	PUNCT
admet-34	292	3	our	our	PRON
admet-34	292	4	model	model	NOUN
admet-34	292	5	was	be	AUX
admet-34	292	6	fitted	fit	VERB
admet-34	292	7	(	(	PUNCT
admet-34	292	8	four	four	NUM
admet-34	292	9	fitting	fitting	ADJ
admet-34	292	10	parameters	parameter	NOUN
admet-34	292	11	)	)	PUNCT
admet-34	292	12	to	to	ADP
admet-34	292	13	experimental	experimental	ADJ
admet-34	292	14	data	datum	NOUN
admet-34	292	15	referring	refer	VERB
admet-34	292	16	to	to	ADP
admet-34	292	17	the	the	DET
admet-34	292	18	oral	oral	ADJ
admet-34	292	19	administration	administration	NOUN
admet-34	292	20	(	(	PUNCT
admet-34	292	21	three	three	NUM
admet-34	292	22	humans	human	NOUN
admet-34	292	23	)	)	PUNCT
admet-34	292	24	of	of	ADP
admet-34	292	25	a	a	DET
admet-34	292	26	commercial	commercial	ADJ
admet-34	292	27	prompt	prompt	ADJ
admet-34	292	28	action	action	NOUN
admet-34	292	29	formulation	formulation	NOUN
admet-34	292	30	containing	contain	VERB
admet-34	292	31	nimesulide	nimesulide	ADV
admet-34	292	32	(	(	PUNCT
admet-34	292	33	100	100	NUM
admet-34	292	34	mg	mg	NOUN
admet-34	292	35	)	)	PUNCT
admet-34	293	1	[	[	X
admet-34	293	2	33	33	NUM
admet-34	293	3	]	]	PUNCT
admet-34	293	4	.	.	PUNCT
admet-34	294	1	fitting	fitting	ADJ
admet-34	294	2	procedure	procedure	NOUN
admet-34	294	3	was	be	AUX
admet-34	294	4	performed	perform	VERB
admet-34	294	5	assuming	assume	VERB
admet-34	294	6	that	that	SCONJ
admet-34	294	7	nimesulide	nimesulide	NOUN
admet-34	294	8	is	be	AUX
admet-34	294	9	embodied	embody	VERB
admet-34	294	10	in	in	ADP
admet-34	294	11	macro	macro	ADJ
admet-34	294	12	-	-	NOUN
admet-34	294	13	crystal	crystal	ADJ
admet-34	294	14	form	form	NOUN
admet-34	294	15	inside	inside	ADP
admet-34	294	16	a	a	DET
admet-34	294	17	polymeric	polymeric	ADJ
admet-34	294	18	carrier	carrier	NOUN
admet-34	294	19	showing	show	VERB
admet-34	294	20	the	the	DET
admet-34	294	21	physical	physical	ADJ
admet-34	294	22	-	-	PUNCT
admet-34	294	23	chemical	chemical	NOUN
admet-34	294	24	characteristics	characteristic	NOUN
admet-34	294	25	reported	report	VERB
admet-34	294	26	in	in	ADP
admet-34	294	27	table	table	NOUN
admet-34	294	28	3	3	NUM
admet-34	294	29	(	(	PUNCT
admet-34	294	30	they	they	PRON
admet-34	294	31	are	be	AUX
admet-34	294	32	similar	similar	ADJ
admet-34	294	33	to	to	ADP
admet-34	294	34	those	those	PRON
admet-34	294	35	competing	compete	VERB
admet-34	294	36	to	to	ADP
admet-34	294	37	polyvinyl	polyvinyl	NOUN
admet-34	294	38	-	-	PUNCT
admet-34	294	39	pyrrolidone	pyrrolidone	VERB
admet-34	294	40	particles	particle	NOUN
admet-34	294	41	considered	consider	VERB
admet-34	294	42	in	in	ADP
admet-34	294	43	the	the	DET
admet-34	294	44	tem	tem	PROPN
admet-34	294	45	case	case	NOUN
admet-34	294	46	)	)	PUNCT
admet-34	294	47	.	.	PUNCT
admet-34	295	1	in	in	ADP
admet-34	295	2	addition	addition	NOUN
admet-34	295	3	,	,	PUNCT
admet-34	295	4	i	i	PRON
admet-34	295	5	glr	glr	PROPN
admet-34	295	6	was	be	AUX
admet-34	295	7	set	set	VERB
admet-34	295	8	to	to	ADP
admet-34	295	9	7.3	7.3	NUM
admet-34	295	10	cm	cm	NOUN
admet-34	295	11	so	so	SCONJ
admet-34	295	12	that	that	SCONJ
admet-34	295	13	the	the	DET
admet-34	295	14	stomach	stomach	NOUN
admet-34	295	15	absorption	absorption	NOUN
admet-34	295	16	surface	surface	NOUN
admet-34	295	17	equals	equal	VERB
admet-34	295	18	the	the	DET
admet-34	295	19	one	one	NOUN
admet-34	295	20	normally	normally	ADV
admet-34	295	21	found	find	VERB
admet-34	295	22	in	in	ADP
admet-34	295	23	humans	human	NOUN
admet-34	295	24	(	(	PUNCT
admet-34	295	25	around	around	ADV
admet-34	295	26	1	1	NUM
admet-34	295	27	m	m	NUM
admet-34	295	28	2	2	NUM
admet-34	296	1	[	[	X
admet-34	296	2	16	16	NUM
admet-34	296	3	]	]	PUNCT
admet-34	296	4	)	)	PUNCT
admet-34	296	5	.	.	PUNCT
admet-34	297	1	figure	figure	NOUN
admet-34	297	2	4a	4a	NOUN
admet-34	297	3	reports	report	VERB
admet-34	297	4	the	the	DET
admet-34	297	5	very	very	ADV
admet-34	297	6	good	good	ADJ
admet-34	297	7	agreement	agreement	NOUN
admet-34	297	8	between	between	ADP
admet-34	297	9	model	model	NOUN
admet-34	297	10	best	well	ADV
admet-34	297	11	fitting	fitting	ADJ
admet-34	297	12	(	(	PUNCT
admet-34	297	13	solid	solid	ADJ
admet-34	297	14	thin	thin	ADJ
admet-34	297	15	line	line	NOUN
admet-34	297	16	)	)	PUNCT
admet-34	297	17	and	and	CCONJ
admet-34	297	18	experimental	experimental	ADJ
admet-34	297	19	data	datum	NOUN
admet-34	297	20	(	(	PUNCT
admet-34	297	21	open	open	ADJ
admet-34	297	22	circles	circle	NOUN
admet-34	297	23	)	)	PUNCT
admet-34	297	24	being	be	AUX
admet-34	297	25	fitting	fitting	ADJ
admet-34	297	26	parameters	parameter	NOUN
admet-34	297	27	mc	mc	PROPN
admet-34	297	28	sc	sc	PROPN
admet-34	298	1	=	=	PROPN
admet-34	298	2	39	39	NUM
admet-34	298	3	g	g	PROPN
admet-34	298	4	/	/	SYM
admet-34	298	5	cm	cm	NOUN
admet-34	298	6	3	3	NUM
admet-34	298	7	,	,	PUNCT
admet-34	298	8	pgl	pgl	NOUN
admet-34	298	9	=	=	SYM
admet-34	298	10	6	6	NUM
admet-34	298	11	*	*	SYM
admet-34	298	12	10	10	NUM
admet-34	298	13	-4	-4	SYM
admet-34	298	14	cm	cm	PROPN
admet-34	298	15	/	/	SYM
admet-34	298	16	s	s	PROPN
admet-34	298	17	,	,	PUNCT
admet-34	298	18	psil	psil	NOUN
admet-34	298	19	=	=	PUNCT
admet-34	298	20	8.3	8.3	NUM
admet-34	298	21	*	*	SYM
admet-34	298	22	10	10	NUM
admet-34	298	23	-5	-5	ADJ
admet-34	298	24	cm	cm	NOUN
admet-34	298	25	/	/	SYM
admet-34	298	26	s	s	PART
admet-34	298	27	and	and	CCONJ
admet-34	298	28	plil	plil	NOUN
admet-34	298	29	=	=	SYM
admet-34	298	30	7	7	NUM
admet-34	298	31	*	*	SYM
admet-34	298	32	10	10	NUM
admet-34	298	33	-5	-5	INTJ
admet-34	298	34	cm	cm	NOUN
admet-34	298	35	/	/	SYM
admet-34	298	36	s.	s.	PROPN
admet-34	299	1	these	these	DET
admet-34	299	2	permeability	permeability	NOUN
admet-34	299	3	values	value	NOUN
admet-34	299	4	indicate	indicate	VERB
admet-34	299	5	that	that	PRON
admet-34	299	6	nimesulide	nimesulide	NOUN
admet-34	299	7	is	be	AUX
admet-34	299	8	rapidly	rapidly	ADV
admet-34	299	9	absorbed	absorb	VERB
admet-34	299	10	by	by	ADP
admet-34	299	11	the	the	DET
admet-34	299	12	gastric	gastric	ADJ
admet-34	299	13	mucosa	mucosa	NOUN
admet-34	299	14	while	while	SCONJ
admet-34	299	15	its	its	PRON
admet-34	299	16	absorption	absorption	NOUN
admet-34	299	17	in	in	ADP
admet-34	299	18	the	the	DET
admet-34	299	19	sil	sil	PROPN
admet-34	299	20	and	and	CCONJ
admet-34	299	21	lil	lil	NOUN
admet-34	299	22	is	be	AUX
admet-34	299	23	slower	slow	ADJ
admet-34	299	24	due	due	ADP
admet-34	299	25	to	to	ADP
admet-34	299	26	the	the	DET
admet-34	299	27	reduction	reduction	NOUN
admet-34	299	28	of	of	ADP
admet-34	299	29	permeability	permeability	NOUN
admet-34	299	30	(	(	PUNCT
admet-34	299	31	one	one	NUM
admet-34	299	32	order	order	NOUN
admet-34	299	33	of	of	ADP
admet-34	299	34	magnitude	magnitude	NOUN
admet-34	299	35	)	)	PUNCT
admet-34	299	36	.	.	PUNCT
admet-34	300	1	these	these	DET
admet-34	300	2	results	result	NOUN
admet-34	300	3	seem	seem	VERB
admet-34	300	4	reasonable	reasonable	ADJ
admet-34	300	5	.	.	PUNCT
admet-34	301	1	indeed	indeed	ADV
admet-34	301	2	,	,	PUNCT
admet-34	301	3	the	the	DET
admet-34	301	4	acid	acid	NOUN
admet-34	301	5	environment	environment	NOUN
admet-34	301	6	of	of	ADP
admet-34	301	7	the	the	DET
admet-34	301	8	stomach	stomach	NOUN
admet-34	301	9	is	be	AUX
admet-34	301	10	particularly	particularly	ADV
admet-34	301	11	favorable	favorable	ADJ
admet-34	301	12	for	for	ADP
admet-34	301	13	the	the	DET
admet-34	301	14	absorption	absorption	NOUN
admet-34	301	15	of	of	ADP
admet-34	301	16	nimesulide	nimesulide	ADV
admet-34	301	17	that	that	SCONJ
admet-34	301	18	,	,	PUNCT
admet-34	301	19	at	at	ADP
admet-34	301	20	low	low	ADJ
admet-34	301	21	ph	ph	NOUN
admet-34	301	22	(	(	PUNCT
admet-34	301	23	<	<	X
admet-34	301	24	3	3	NUM
admet-34	301	25	;	;	PUNCT
admet-34	301	26	nimesulide	nimesulide	ADV
admet-34	301	27	is	be	AUX
admet-34	301	28	a	a	DET
admet-34	301	29	weak	weak	ADJ
admet-34	301	30	acid	acid	NOUN
admet-34	301	31	with	with	ADP
admet-34	301	32	pka	pka	PROPN
admet-34	301	33	=	=	SYM
admet-34	301	34	6.46	6.46	NUM
admet-34	301	35	)	)	PUNCT
admet-34	301	36	is	be	AUX
admet-34	301	37	completely	completely	ADV
admet-34	301	38	un	un	ADJ
admet-34	301	39	-	-	ADJ
admet-34	301	40	dissociated	dissociated	ADJ
admet-34	301	41	(	(	PUNCT
admet-34	301	42	un	un	ADJ
admet-34	301	43	-	-	ADJ
admet-34	301	44	ionized	ionized	ADJ
admet-34	301	45	)	)	PUNCT
admet-34	301	46	and	and	CCONJ
admet-34	301	47	this	this	DET
admet-34	301	48	condition	condition	NOUN
admet-34	301	49	favors	favor	VERB
admet-34	301	50	its	its	PRON
admet-34	301	51	passive	passive	ADJ
admet-34	301	52	absorption	absorption	NOUN
admet-34	301	53	by	by	ADP
admet-34	301	54	the	the	DET
admet-34	301	55	lipid	lipid	NOUN
admet-34	301	56	mucosal	mucosal	NOUN
admet-34	301	57	membrane	membrane	NOUN
admet-34	301	58	.	.	PUNCT
admet-34	302	1	on	on	ADP
admet-34	302	2	the	the	DET
admet-34	302	3	contrary	contrary	NOUN
admet-34	302	4	,	,	PUNCT
admet-34	302	5	for	for	ADP
admet-34	302	6	higher	high	ADJ
admet-34	302	7	ph	ph	NOUN
admet-34	302	8	,	,	PUNCT
admet-34	302	9	such	such	ADJ
admet-34	302	10	as	as	ADP
admet-34	302	11	that	that	PRON
admet-34	302	12	found	find	VERB
admet-34	302	13	in	in	ADP
admet-34	302	14	the	the	DET
admet-34	302	15	small	small	ADJ
admet-34	302	16	intestine	intestine	NOUN
admet-34	302	17	,	,	PUNCT
admet-34	302	18	nimesulide	nimesulide	ADV
admet-34	302	19	is	be	AUX
admet-34	302	20	partially	partially	ADV
admet-34	302	21	or	or	CCONJ
admet-34	302	22	totally	totally	ADV
admet-34	302	23	dissociated	dissociate	VERB
admet-34	302	24	(	(	PUNCT
admet-34	302	25	ionized	ionized	ADJ
admet-34	302	26	)	)	PUNCT
admet-34	302	27	and	and	CCONJ
admet-34	302	28	this	this	DET
admet-34	302	29	condition	condition	NOUN
admet-34	302	30	hinders	hinder	VERB
admet-34	302	31	nimesulide	nimesulide	ADV
admet-34	302	32	crossing	crossing	NOUN
admet-34	302	33	of	of	ADP
admet-34	302	34	the	the	DET
admet-34	302	35	lipophilic	lipophilic	ADJ
admet-34	302	36	mucosal	mucosal	NOUN
admet-34	302	37	membrane	membrane	NOUN
admet-34	302	38	.	.	PUNCT
admet-34	303	1	accordingly	accordingly	ADV
admet-34	303	2	,	,	PUNCT
admet-34	303	3	chemical	chemical	NOUN
admet-34	303	4	and	and	CCONJ
admet-34	303	5	physical	physical	ADJ
admet-34	303	6	properties	property	NOUN
admet-34	303	7	should	should	AUX
admet-34	303	8	be	be	AUX
admet-34	303	9	responsible	responsible	ADJ
admet-34	303	10	for	for	ADP
admet-34	303	11	the	the	DET
admet-34	303	12	nimesulide	nimesulide	ADJ
admet-34	303	13	different	different	ADJ
admet-34	303	14	permeability	permeability	NOUN
admet-34	303	15	through	through	ADP
admet-34	303	16	the	the	DET
admet-34	303	17	gi	gi	PROPN
admet-34	303	18	tract	tract	NOUN
admet-34	303	19	rather	rather	ADV
admet-34	303	20	than	than	ADP
admet-34	303	21	other	other	ADJ
admet-34	303	22	reasons	reason	NOUN
admet-34	303	23	such	such	ADJ
admet-34	303	24	as	as	ADP
admet-34	303	25	the	the	DET
admet-34	303	26	effect	effect	NOUN
admet-34	303	27	of	of	ADP
admet-34	303	28	intestinal	intestinal	ADJ
admet-34	303	29	wall	wall	NOUN
admet-34	303	30	transporters	transporter	NOUN
admet-34	303	31	.	.	PUNCT
admet-34	304	1	these	these	DET
admet-34	304	2	chemico	chemico	ADJ
admet-34	304	3	-	-	ADJ
admet-34	304	4	phyiscal	phyiscal	ADJ
admet-34	304	5	considerations	consideration	NOUN
admet-34	304	6	have	have	AUX
admet-34	304	7	been	be	AUX
admet-34	304	8	supported	support	VERB
admet-34	304	9	by	by	ADP
admet-34	304	10	studies	study	NOUN
admet-34	304	11	about	about	ADP
admet-34	304	12	the	the	DET
admet-34	304	13	regional	regional	ADJ
admet-34	304	14	absorption	absorption	NOUN
admet-34	304	15	of	of	ADP
admet-34	304	16	nimesulide	nimesulide	NOUN
admet-34	305	1	[	[	X
admet-34	305	2	34	34	NUM
admet-34	305	3	,	,	PUNCT
admet-34	305	4	35	35	NUM
admet-34	305	5	]	]	PUNCT
admet-34	305	6	,	,	PUNCT
admet-34	305	7	led	lead	VERB
admet-34	305	8	on	on	ADP
admet-34	305	9	healthy	healthy	ADJ
admet-34	305	10	volunteers	volunteer	NOUN
admet-34	305	11	(	(	PUNCT
admet-34	305	12	gamma	gamma	NOUN
admet-34	305	13	scintigraphy	scintigraphy	NOUN
admet-34	305	14	)	)	PUNCT
admet-34	305	15	.	.	PUNCT
admet-34	306	1	these	these	DET
admet-34	306	2	studies	study	NOUN
admet-34	306	3	proved	prove	VERB
admet-34	306	4	that	that	SCONJ
admet-34	306	5	stomach	stomach	NOUN
admet-34	306	6	and	and	CCONJ
admet-34	306	7	proximal	proximal	ADJ
admet-34	306	8	small	small	ADJ
admet-34	306	9	bowel	bowel	NOUN
admet-34	306	10	account	account	NOUN
admet-34	306	11	for	for	ADP
admet-34	306	12	40	40	NUM
admet-34	306	13	%	%	NOUN
admet-34	306	14	of	of	ADP
admet-34	306	15	nimesulide	nimesulide	ADJ
admet-34	306	16	absorption	absorption	NOUN
admet-34	306	17	.	.	PUNCT
admet-34	307	1	del	del	PROPN
admet-34	307	2	cont	cont	PROPN
admet-34	307	3	et	et	PROPN
admet-34	307	4	al	al	PROPN
admet-34	307	5	.	.	PROPN
admet-34	307	6	admet	admet	PROPN
admet-34	307	7	&	&	CCONJ
admet-34	307	8	dmpk	dmpk	PROPN
admet-34	307	9	2(2	2(2	NUM
admet-34	307	10	)	)	PUNCT
admet-34	307	11	(	(	PUNCT
admet-34	307	12	2014	2014	NUM
admet-34	307	13	)	)	PUNCT
admet-34	307	14	80	80	NUM
admet-34	307	15	-	-	SYM
admet-34	307	16	97	97	NUM
admet-34	307	17	92	92	NUM
admet-34	307	18	table	table	NOUN
admet-34	307	19	3	3	NUM
admet-34	307	20	.	.	PUNCT
admet-34	307	21	model	model	NOUN
admet-34	307	22	parameters	parameter	NOUN
admet-34	307	23	referring	refer	VERB
admet-34	307	24	to	to	ADP
admet-34	307	25	nimesulide	nimesulide	NOUN
admet-34	307	26	(	(	PUNCT
admet-34	307	27	release	release	VERB
admet-34	307	28	environment	environment	NOUN
admet-34	307	29	vr	vr	NOUN
admet-34	307	30	=	=	NOUN
admet-34	307	31	250	250	NUM
admet-34	307	32	cm	cm	NUM
admet-34	307	33	3	3	NUM
admet-34	307	34	,	,	PUNCT
admet-34	307	35	polymeric	polymeric	ADJ
admet-34	307	36	carrier	carrier	NOUN
admet-34	307	37	density	density	NOUN
admet-34	307	38	1.2	1.2	NUM
admet-34	307	39	g	g	NOUN
admet-34	307	40	/	/	SYM
admet-34	307	41	cm	cm	NOUN
admet-34	307	42	3	3	NUM
admet-34	307	43	)	)	PUNCT
admet-34	307	44	pk	pk	NOUN
admet-34	307	45	parameters	parameter	NOUN
admet-34	307	46	[	[	X
admet-34	307	47	10	10	NUM
admet-34	307	48	,	,	PUNCT
admet-34	307	49	16	16	NUM
admet-34	307	50	14	14	NUM
admet-34	307	51	,	,	PUNCT
admet-34	307	52	30	30	NUM
admet-34	307	53	28	28	NUM
admet-34	307	54	]	]	PUNCT
admet-34	307	55	vp(cm3	vp(cm3	NUM
admet-34	307	56	)	)	PUNCT
admet-34	307	57	vl(cm3	vl(cm3	NOUN
admet-34	307	58	)	)	PUNCT
admet-34	307	59	vgics(cm3	vgics(cm3	NOUN
admet-34	307	60	)	)	PUNCT
admet-34	307	61	vt(cm3	vt(cm3	NUM
admet-34	307	62	)	)	PUNCT
admet-34	307	63	5000	5000	NUM
admet-34	307	64	1500	1500	NUM
admet-34	307	65	9.96	9.96	NUM
admet-34	307	66	13000	13000	NUM
admet-34	307	67	qpv(cm3	qpv(cm3	PROPN
admet-34	307	68	/	/	SYM
admet-34	307	69	s	s	PART
admet-34	307	70	)	)	PUNCT
admet-34	307	71	qha(cm3	qha(cm3	PROPN
admet-34	307	72	/	/	SYM
admet-34	307	73	s	s	PART
admet-34	307	74	)	)	PUNCT
admet-34	307	75	qhv(cm3	qhv(cm3	PROPN
admet-34	307	76	/	/	SYM
admet-34	307	77	s	s	PART
admet-34	307	78	)	)	PUNCT
admet-34	307	79	clh(cm3	clh(cm3	PROPN
admet-34	307	80	/	/	SYM
admet-34	307	81	s	s	NOUN
admet-34	307	82	)	)	PUNCT
admet-34	307	83	16.25	16.25	NUM
admet-34	307	84	5.41	5.41	NUM
admet-34	307	85	21.6	21.6	NUM
admet-34	307	86	0.49	0.49	NUM
admet-34	307	87	re	re	ADP
admet-34	307	88	elk	elk	PROPN
admet-34	307	89	(	(	PUNCT
admet-34	307	90	1	1	NUM
admet-34	307	91	/	/	SYM
admet-34	307	92	s	s	NOUN
admet-34	307	93	)	)	PUNCT
admet-34	307	94	kel(1	kel(1	NOUN
admet-34	307	95	/	/	SYM
admet-34	307	96	s	s	NOUN
admet-34	307	97	)	)	PUNCT
admet-34	307	98	ktp(1	ktp(1	NOUN
admet-34	307	99	/	/	SYM
admet-34	307	100	s	s	NOUN
admet-34	307	101	)	)	PUNCT
admet-34	307	102	ktp(1	ktp(1	NOUN
admet-34	307	103	/	/	SYM
admet-34	307	104	s	s	PROPN
admet-34	307	105	)	)	PUNCT
admet-34	307	106	0.0	0.0	NUM
admet-34	307	107	0.0	0.0	NUM
admet-34	307	108	10	10	NUM
admet-34	307	109	-	-	SYM
admet-34	307	110	6	6	NUM
admet-34	307	111	10	10	NUM
admet-34	307	112	-	-	SYM
admet-34	307	113	6	6	NUM
admet-34	307	114	tgl(s	tgl(s	NOUN
admet-34	307	115	)	)	PUNCT
admet-34	307	116	rgl(cm	rgl(cm	NOUN
admet-34	307	117	)	)	PUNCT
admet-34	308	1	i	i	PRON
admet-34	308	2	glr	glr	PROPN
admet-34	308	3	(	(	PUNCT
admet-34	308	4	cm	cm	NOUN
admet-34	308	5	)	)	PUNCT
admet-34	308	6	pgl(cm	pgl(cm	NOUN
admet-34	308	7	/	/	SYM
admet-34	308	8	s	s	NOUN
admet-34	308	9	)	)	PUNCT
admet-34	308	10	2880	2880	NUM
admet-34	308	11	7.5	7.5	NUM
admet-34	308	12	7.3	7.3	NUM
admet-34	308	13	6.0	6.0	NUM
admet-34	308	14	*	*	NUM
admet-34	308	15	10	10	NUM
admet-34	308	16	-	-	SYM
admet-34	308	17	4	4	NUM
admet-34	308	18	tsil(s	tsil(s	NOUN
admet-34	308	19	)	)	PUNCT
admet-34	308	20	rsil(cm	rsil(cm	NOUN
admet-34	308	21	)	)	PUNCT
admet-34	309	1	i	i	PRON
admet-34	309	2	silr	silr	NOUN
admet-34	309	3	(	(	PUNCT
admet-34	309	4	cm	cm	NOUN
admet-34	309	5	)	)	PUNCT
admet-34	309	6	psil(cm	psil(cm	NOUN
admet-34	309	7	/	/	SYM
admet-34	309	8	s	s	NOUN
admet-34	309	9	)	)	PUNCT
admet-34	309	10	11520.0	11520.0	NUM
admet-34	309	11	2.5	2.5	NUM
admet-34	309	12	0.0	0.0	NUM
admet-34	309	13	8.3	8.3	NUM
admet-34	309	14	*	*	SYM
admet-34	309	15	10	10	NUM
admet-34	309	16	-	-	SYM
admet-34	309	17	5	5	NUM
admet-34	309	18	til(s	til(s	NOUN
admet-34	309	19	)	)	PUNCT
admet-34	309	20	rlil(cm	rlil(cm	NOUN
admet-34	309	21	)	)	PUNCT
admet-34	310	1	i	i	PRON
admet-34	310	2	lilr	lilr	VERB
admet-34	310	3	(	(	PUNCT
admet-34	310	4	cm	cm	NOUN
admet-34	310	5	)	)	PUNCT
admet-34	310	6	plil(cm	plil(cm	NOUN
admet-34	310	7	/	/	SYM
admet-34	310	8	s	s	PROPN
admet-34	310	9	)	)	PUNCT
admet-34	310	10	115200.0	115200.0	NUM
admet-34	310	11	2.5	2.5	NUM
admet-34	310	12	0.0	0.0	NUM
admet-34	310	13	7.0	7.0	NUM
admet-34	310	14	*	*	SYM
admet-34	310	15	10	10	NUM
admet-34	310	16	-	-	SYM
admet-34	310	17	5	5	NUM
admet-34	310	18	delivery	delivery	NOUN
admet-34	310	19	parameters	parameter	NOUN
admet-34	311	1	[	[	X
admet-34	311	2	11	11	NUM
admet-34	311	3	,	,	PUNCT
admet-34	311	4	19	19	NUM
admet-34	311	5	17	17	NUM
admet-34	311	6	]	]	X
admet-34	311	7	ceq(g	ceq(g	PROPN
admet-34	311	8	/	/	SYM
admet-34	311	9	cm3	cm3	PROPN
admet-34	311	10	)	)	PUNCT
admet-34	311	11	eq(s	eq(s	NOUN
admet-34	311	12	)	)	PUNCT
admet-34	311	13	deq(cm2	deq(cm2	PROPN
admet-34	311	14	/	/	SYM
admet-34	311	15	s	s	NOUN
admet-34	311	16	)	)	PUNCT
admet-34	311	17	d0(cm2	d0(cm2	PROPN
admet-34	311	18	/	/	SYM
admet-34	311	19	s	s	PROPN
admet-34	311	20	)	)	PUNCT
admet-34	311	21	0.31	0.31	NUM
admet-34	311	22	0.35	0.35	NUM
admet-34	311	23	10	10	NUM
admet-34	311	24	-	-	SYM
admet-34	311	25	7	7	NUM
admet-34	311	26	10	10	NUM
admet-34	311	27	-	-	SYM
admet-34	311	28	8	8	NUM
admet-34	311	29	g(cm3	g(cm3	NOUN
admet-34	311	30	/	/	SYM
admet-34	311	31	g	g	NOUN
admet-34	311	32	)	)	PUNCT
admet-34	311	33	f(cm3	f(cm3	NOUN
admet-34	311	34	/	/	SYM
admet-34	311	35	g	g	NOUN
admet-34	311	36	)	)	PUNCT
admet-34	311	37	dds(cm2	dds(cm2	PROPN
admet-34	311	38	/	/	SYM
admet-34	311	39	s	s	NOUN
admet-34	311	40	)	)	PUNCT
admet-34	311	41	kp(-	kp(-	PROPN
admet-34	311	42	)	)	PUNCT
admet-34	311	43	5.0	5.0	NUM
admet-34	311	44	12.0	12.0	NUM
admet-34	311	45	10	10	NUM
admet-34	311	46	-	-	SYM
admet-34	311	47	6	6	NUM
admet-34	311	48	1.0	1.0	NUM
admet-34	311	49	am	am	NOUN
admet-34	311	50	sc	sc	PROPN
admet-34	311	51	(	(	PUNCT
admet-34	311	52	g	g	PROPN
admet-34	311	53	/	/	SYM
admet-34	311	54	cm3	cm3	PROPN
admet-34	311	55	)	)	PUNCT
admet-34	311	56	k(1	k(1	PROPN
admet-34	311	57	/	/	SYM
admet-34	311	58	s	s	PROPN
admet-34	311	59	)	)	PUNCT
admet-34	311	60	kr(1	kr(1	PROPN
admet-34	311	61	/	/	SYM
admet-34	311	62	s	s	NOUN
admet-34	311	63	)	)	PUNCT
admet-34	311	64	krb(1	krb(1	PROPN
admet-34	311	65	/	/	SYM
admet-34	311	66	s	s	PROPN
admet-34	311	67	)	)	PUNCT
admet-34	311	68	4108	4108	NUM
admet-34	311	69	2.0	2.0	NUM
admet-34	311	70	0.06	0.06	NUM
admet-34	311	71	0.0	0.0	NUM
admet-34	311	72	mc	mc	PROPN
admet-34	311	73	sc	sc	PROPN
admet-34	311	74	(	(	PUNCT
admet-34	311	75	g	g	PROPN
admet-34	311	76	/	/	SYM
admet-34	311	77	cm3	cm3	NOUN
admet-34	311	78	)	)	PUNCT
admet-34	311	79	ph	ph	X
admet-34	311	80	>	>	X
admet-34	311	81	6.4	6.4	NUM
admet-34	311	82	mc	mc	PROPN
admet-34	311	83	sc	sc	PROPN
admet-34	311	84	(	(	PUNCT
admet-34	311	85	g	g	PROPN
admet-34	311	86	/	/	SYM
admet-34	311	87	cm3	cm3	NOUN
admet-34	311	88	)	)	PUNCT
admet-34	311	89	ph	ph	NOUN
admet-34	311	90	<	<	X
admet-34	311	91	6.4	6.4	NUM
admet-34	311	92	100	100	NUM
admet-34	311	93	39	39	NUM
admet-34	311	94	as	as	ADP
admet-34	311	95	in	in	ADP
admet-34	311	96	the	the	DET
admet-34	311	97	tem	tem	PROPN
admet-34	311	98	case	case	NOUN
admet-34	311	99	,	,	PUNCT
admet-34	311	100	nimesulide	nimesulide	ADP
admet-34	311	101	absorption	absorption	NOUN
admet-34	311	102	can	can	AUX
admet-34	311	103	be	be	AUX
admet-34	311	104	improved	improve	VERB
admet-34	311	105	by	by	ADP
admet-34	311	106	considering	consider	VERB
admet-34	311	107	its	its	PRON
admet-34	311	108	amorphous	amorphous	ADJ
admet-34	311	109	form	form	NOUN
admet-34	311	110	.	.	PUNCT
admet-34	312	1	figure	figure	NOUN
admet-34	312	2	4a	4a	NOUN
admet-34	312	3	shows	show	VERB
admet-34	312	4	the	the	DET
admet-34	312	5	predicted	predict	VERB
admet-34	312	6	plasma	plasma	NOUN
admet-34	312	7	concentration	concentration	NOUN
admet-34	312	8	cp	cp	INTJ
admet-34	312	9	(	(	PUNCT
admet-34	312	10	thick	thick	ADJ
admet-34	312	11	line	line	NOUN
admet-34	312	12	)	)	PUNCT
admet-34	312	13	in	in	ADP
admet-34	312	14	the	the	DET
admet-34	312	15	case	case	NOUN
admet-34	312	16	of	of	ADP
admet-34	312	17	amorphous	amorphous	ADJ
admet-34	312	18	nimesulide	nimesulide	NOUN
admet-34	312	19	assuming	assume	VERB
admet-34	312	20	,	,	PUNCT
admet-34	312	21	as	as	SCONJ
admet-34	312	22	done	do	VERB
admet-34	312	23	in	in	ADP
admet-34	312	24	the	the	DET
admet-34	312	25	tem	tem	PROPN
admet-34	312	26	case	case	NOUN
admet-34	312	27	,	,	PUNCT
admet-34	312	28	that	that	SCONJ
admet-34	312	29	no	no	PRON
admet-34	312	30	re	re	NOUN
admet-34	312	31	-	-	NOUN
admet-34	312	32	crystallisation	crystallisation	NOUN
admet-34	312	33	takes	take	VERB
admet-34	312	34	place	place	NOUN
admet-34	312	35	(	(	PUNCT
admet-34	312	36	krb	krb	X
admet-34	312	37	=	=	SYM
admet-34	312	38	0	0	NUM
admet-34	312	39	)	)	PUNCT
admet-34	312	40	.	.	PUNCT
admet-34	313	1	thus	thus	ADV
admet-34	313	2	,	,	PUNCT
admet-34	313	3	this	this	DET
admet-34	313	4	prediction	prediction	NOUN
admet-34	313	5	should	should	AUX
admet-34	313	6	represent	represent	VERB
admet-34	313	7	the	the	DET
admet-34	313	8	maximum	maximum	ADJ
admet-34	313	9	expected	expect	VERB
admet-34	313	10	effect	effect	NOUN
admet-34	313	11	of	of	ADP
admet-34	313	12	amorphous	amorphous	ADJ
admet-34	313	13	nimesulide	nimesulide	NOUN
admet-34	313	14	.	.	PUNCT
admet-34	314	1	it	it	PRON
admet-34	314	2	can	can	AUX
admet-34	314	3	be	be	AUX
admet-34	314	4	seen	see	VERB
admet-34	314	5	that	that	SCONJ
admet-34	314	6	the	the	DET
admet-34	314	7	maximum	maximum	ADJ
admet-34	314	8	concentration	concentration	NOUN
admet-34	314	9	is	be	AUX
admet-34	314	10	considerably	considerably	ADV
admet-34	314	11	increased	increase	VERB
admet-34	314	12	and	and	CCONJ
admet-34	314	13	,	,	PUNCT
admet-34	314	14	up	up	ADP
admet-34	314	15	to	to	ADP
admet-34	314	16	about	about	ADV
admet-34	314	17	5	5	NUM
admet-34	314	18	hours	hour	NOUN
admet-34	314	19	,	,	PUNCT
admet-34	314	20	drug	drug	NOUN
admet-34	314	21	concentration	concentration	NOUN
admet-34	314	22	(	(	PUNCT
admet-34	314	23	thick	thick	ADJ
admet-34	314	24	line	line	NOUN
admet-34	314	25	)	)	PUNCT
admet-34	314	26	is	be	AUX
admet-34	314	27	higher	high	ADJ
admet-34	314	28	than	than	ADP
admet-34	314	29	that	that	PRON
admet-34	314	30	of	of	ADP
admet-34	314	31	the	the	DET
admet-34	314	32	macro	macro	ADJ
admet-34	314	33	-	-	NOUN
admet-34	314	34	crystal	crystal	NOUN
admet-34	314	35	case	case	NOUN
admet-34	314	36	(	(	PUNCT
admet-34	314	37	thin	thin	ADJ
admet-34	314	38	line	line	NOUN
admet-34	314	39	)	)	PUNCT
admet-34	314	40	.	.	PUNCT
admet-34	315	1	this	this	DET
admet-34	315	2	behavior	behavior	NOUN
admet-34	315	3	in	in	ADP
admet-34	315	4	the	the	DET
admet-34	315	5	plasma	plasma	NOUN
admet-34	315	6	is	be	AUX
admet-34	315	7	explained	explain	VERB
admet-34	315	8	by	by	ADP
admet-34	315	9	figure	figure	NOUN
admet-34	315	10	4b	4b	PROPN
admet-34	315	11	where	where	SCONJ
admet-34	315	12	drug	drug	NOUN
admet-34	315	13	concentration	concentration	NOUN
admet-34	315	14	in	in	ADP
admet-34	315	15	the	the	DET
admet-34	315	16	release	release	NOUN
admet-34	315	17	environment	environment	NOUN
admet-34	315	18	(	(	PUNCT
admet-34	315	19	cr	cr	NOUN
admet-34	315	20	)	)	PUNCT
admet-34	315	21	is	be	AUX
admet-34	315	22	reported	report	VERB
admet-34	315	23	for	for	ADP
admet-34	315	24	the	the	DET
admet-34	315	25	amorphous	amorphous	ADJ
admet-34	315	26	drug	drug	NOUN
admet-34	315	27	(	(	PUNCT
admet-34	315	28	thick	thick	ADJ
admet-34	315	29	line	line	NOUN
admet-34	315	30	)	)	PUNCT
admet-34	315	31	and	and	CCONJ
admet-34	315	32	the	the	DET
admet-34	315	33	macro	macro	ADJ
admet-34	315	34	-	-	ADJ
admet-34	315	35	crystalline	crystalline	ADJ
admet-34	315	36	drug	drug	NOUN
admet-34	315	37	(	(	PUNCT
admet-34	315	38	thin	thin	ADJ
admet-34	315	39	line	line	NOUN
admet-34	315	40	)	)	PUNCT
admet-34	315	41	.	.	PUNCT
admet-34	316	1	basically	basically	ADV
admet-34	316	2	,	,	PUNCT
admet-34	316	3	in	in	ADP
admet-34	316	4	the	the	DET
admet-34	316	5	amorphous	amorphous	ADJ
admet-34	316	6	case	case	NOUN
admet-34	316	7	,	,	PUNCT
admet-34	316	8	nimesulide	nimesulide	ADV
admet-34	316	9	is	be	AUX
admet-34	316	10	rapidly	rapidly	ADV
admet-34	316	11	released	release	VERB
admet-34	316	12	in	in	ADP
admet-34	316	13	the	the	DET
admet-34	316	14	first	first	ADJ
admet-34	316	15	6	6	NUM
admet-34	316	16	minutes	minute	NOUN
admet-34	316	17	and	and	CCONJ
admet-34	316	18	its	its	PRON
admet-34	316	19	concentration	concentration	NOUN
admet-34	316	20	becomes	become	VERB
admet-34	316	21	about	about	ADV
admet-34	316	22	one	one	NUM
admet-34	316	23	order	order	NOUN
admet-34	316	24	of	of	ADP
admet-34	316	25	magnitude	magnitude	NOUN
admet-34	316	26	higher	high	ADJ
admet-34	316	27	than	than	ADP
admet-34	316	28	that	that	DET
admet-34	316	29	corresponding	correspond	VERB
admet-34	316	30	to	to	ADP
admet-34	316	31	the	the	DET
admet-34	316	32	macro	macro	ADJ
admet-34	316	33	-	-	NOUN
admet-34	316	34	crystal	crystal	NOUN
admet-34	316	35	case	case	NOUN
admet-34	316	36	.	.	PUNCT
admet-34	317	1	this	this	PRON
admet-34	317	2	means	mean	VERB
admet-34	317	3	that	that	SCONJ
admet-34	317	4	its	its	PRON
admet-34	317	5	onset	onset	NOUN
admet-34	317	6	of	of	ADP
admet-34	317	7	action	action	NOUN
admet-34	317	8	is	be	AUX
admet-34	317	9	considerably	considerably	ADV
admet-34	317	10	increased	increase	VERB
admet-34	317	11	,	,	PUNCT
admet-34	317	12	a	a	DET
admet-34	317	13	desirable	desirable	ADJ
admet-34	317	14	feature	feature	NOUN
admet-34	317	15	for	for	ADP
admet-34	317	16	a	a	DET
admet-34	317	17	rapid	rapid	ADJ
admet-34	317	18	pain	pain	NOUN
admet-34	317	19	relief	relief	NOUN
admet-34	317	20	.	.	PUNCT
admet-34	318	1	also	also	ADV
admet-34	318	2	in	in	ADP
admet-34	318	3	this	this	DET
admet-34	318	4	case	case	NOUN
admet-34	318	5	,	,	PUNCT
admet-34	318	6	the	the	DET
admet-34	318	7	time	time	NOUN
admet-34	318	8	evolutions	evolution	NOUN
admet-34	318	9	of	of	ADP
admet-34	318	10	drug	drug	NOUN
admet-34	318	11	concentration	concentration	NOUN
admet-34	318	12	in	in	ADP
admet-34	318	13	the	the	DET
admet-34	318	14	cigs	cig	NOUN
admet-34	318	15	(	(	PUNCT
admet-34	318	16	cgics	cgic	NOUN
admet-34	318	17	)	)	PUNCT
admet-34	318	18	and	and	CCONJ
admet-34	318	19	in	in	ADP
admet-34	318	20	the	the	DET
admet-34	318	21	liver	liver	NOUN
admet-34	318	22	(	(	PUNCT
admet-34	318	23	cl	cl	NOUN
admet-34	318	24	)	)	PUNCT
admet-34	318	25	are	be	AUX
admet-34	318	26	substantially	substantially	ADV
admet-34	318	27	equal	equal	ADJ
admet-34	318	28	to	to	ADP
admet-34	318	29	the	the	DET
admet-34	318	30	cp	cp	PROPN
admet-34	318	31	one	one	NUM
admet-34	318	32	and	and	CCONJ
admet-34	318	33	the	the	DET
admet-34	318	34	reasons	reason	NOUN
admet-34	318	35	are	be	AUX
admet-34	318	36	the	the	DET
admet-34	318	37	same	same	ADJ
admet-34	318	38	as	as	ADP
admet-34	318	39	the	the	DET
admet-34	318	40	theophylline	theophylline	NOUN
admet-34	318	41	case	case	NOUN
admet-34	318	42	’s	’s	X
admet-34	318	43	.	.	PUNCT
admet-34	319	1	again	again	ADV
admet-34	319	2	,	,	PUNCT
admet-34	319	3	drug	drug	NOUN
admet-34	319	4	concentration	concentration	NOUN
admet-34	319	5	(	(	PUNCT
admet-34	319	6	ct	ct	NOUN
admet-34	319	7	)	)	PUNCT
admet-34	319	8	in	in	ADP
admet-34	319	9	the	the	DET
admet-34	319	10	scarcely	scarcely	ADV
admet-34	319	11	perfused	perfused	ADJ
admet-34	319	12	tissues	tissue	NOUN
admet-34	319	13	and	and	CCONJ
admet-34	319	14	organs	organ	NOUN
admet-34	319	15	monotonically	monotonically	ADV
admet-34	319	16	increases	increase	VERB
admet-34	319	17	reaching	reach	VERB
admet-34	319	18	,	,	PUNCT
admet-34	319	19	for	for	ADP
admet-34	319	20	all	all	DET
admet-34	319	21	formulations	formulation	NOUN
admet-34	319	22	,	,	PUNCT
admet-34	319	23	values	value	NOUN
admet-34	319	24	that	that	PRON
admet-34	319	25	are	be	AUX
admet-34	319	26	about	about	ADV
admet-34	319	27	two	two	NUM
admet-34	319	28	order	order	NOUN
admet-34	319	29	of	of	ADP
admet-34	319	30	magnitude	magnitude	NOUN
admet-34	319	31	smaller	small	ADJ
admet-34	319	32	than	than	ADP
admet-34	319	33	cp	cp	PROPN
admet-34	319	34	.	.	PUNCT
admet-34	320	1	the	the	DET
admet-34	320	2	abrupt	abrupt	ADJ
admet-34	320	3	increase	increase	NOUN
admet-34	320	4	of	of	ADP
admet-34	320	5	cr	cr	PROPN
admet-34	320	6	occurring	occur	VERB
admet-34	320	7	after	after	ADP
admet-34	320	8	1	1	NUM
admet-34	320	9	h	h	NOUN
admet-34	320	10	,	,	PUNCT
admet-34	320	11	in	in	ADP
admet-34	320	12	both	both	CCONJ
admet-34	320	13	the	the	DET
admet-34	320	14	crystalline	crystalline	ADJ
admet-34	320	15	and	and	CCONJ
admet-34	320	16	amorphous	amorphous	ADJ
admet-34	320	17	case	case	NOUN
admet-34	320	18	,	,	PUNCT
admet-34	320	19	is	be	AUX
admet-34	320	20	simply	simply	ADV
admet-34	320	21	due	due	ADJ
admet-34	320	22	to	to	ADP
admet-34	320	23	the	the	DET
admet-34	320	24	reduced	reduce	VERB
admet-34	320	25	value	value	NOUN
admet-34	320	26	of	of	ADP
admet-34	320	27	drug	drug	NOUN
admet-34	320	28	permeability	permeability	NOUN
admet-34	320	29	in	in	ADP
admet-34	320	30	the	the	DET
admet-34	320	31	lil	lil	PROPN
admet-34	320	32	.	.	PUNCT
admet-34	321	1	indeed	indeed	ADV
admet-34	321	2	,	,	PUNCT
admet-34	321	3	permeability	permeability	NOUN
admet-34	321	4	reduction	reduction	NOUN
admet-34	321	5	implies	imply	VERB
admet-34	321	6	the	the	DET
admet-34	321	7	decrease	decrease	NOUN
admet-34	321	8	of	of	ADP
admet-34	321	9	the	the	DET
admet-34	321	10	drug	drug	NOUN
admet-34	321	11	flux	flux	PROPN
admet-34	321	12	admet	admet	PROPN
admet-34	321	13	&	&	CCONJ
admet-34	321	14	dmpk	dmpk	PROPN
admet-34	321	15	2(2	2(2	NUM
admet-34	321	16	)	)	PUNCT
admet-34	321	17	(	(	PUNCT
admet-34	321	18	2014	2014	NUM
admet-34	321	19	)	)	PUNCT
admet-34	321	20	80	80	NUM
admet-34	321	21	-	-	SYM
admet-34	321	22	97	97	NUM
admet-34	321	23	in	in	ADP
admet-34	321	24	vivo	vivo	ADJ
admet-34	321	25	drug	drug	NOUN
admet-34	321	26	release	release	NOUN
admet-34	321	27	and	and	CCONJ
admet-34	321	28	absorption	absorption	NOUN
admet-34	321	29	doi	doi	NOUN
admet-34	321	30	:	:	PUNCT
admet-34	321	31	10.5599	10.5599	NUM
admet-34	321	32	/	/	SYM
admet-34	321	33	admet.2.2.34	admet.2.2.34	ADP
admet-34	321	34	93	93	NUM
admet-34	321	35	leaving	leave	VERB
admet-34	321	36	the	the	DET
admet-34	321	37	release	release	NOUN
admet-34	321	38	environment	environment	NOUN
admet-34	321	39	and	and	CCONJ
admet-34	321	40	this	this	PRON
admet-34	321	41	,	,	PUNCT
admet-34	321	42	in	in	ADP
admet-34	321	43	turn	turn	NOUN
admet-34	321	44	,	,	PUNCT
admet-34	321	45	determines	determine	VERB
admet-34	321	46	a	a	DET
admet-34	321	47	drug	drug	NOUN
admet-34	321	48	concentration	concentration	NOUN
admet-34	321	49	increase	increase	NOUN
admet-34	321	50	in	in	ADP
admet-34	321	51	the	the	DET
admet-34	321	52	release	release	NOUN
admet-34	321	53	environment	environment	NOUN
admet-34	321	54	.	.	PUNCT
admet-34	322	1	0	0	NUM
admet-34	323	1	2	2	NUM
admet-34	323	2	4	4	NUM
admet-34	323	3	6	6	NUM
admet-34	323	4	8	8	NUM
admet-34	323	5	10	10	NUM
admet-34	323	6	12	12	NUM
admet-34	323	7	0	0	NUM
admet-34	323	8	4	4	NUM
admet-34	323	9	8	8	NUM
admet-34	323	10	12	12	NUM
admet-34	323	11	16	16	NUM
admet-34	323	12	20	20	NUM
admet-34	323	13	24	24	NUM
admet-34	323	14	c	c	NOUN
admet-34	323	15	p	p	NOUN
admet-34	323	16	(	(	PUNCT
admet-34	323	17			NOUN
admet-34	323	18	g	g	NOUN
admet-34	323	19	/c	/c	PUNCT
admet-34	323	20	m	m	NOUN
admet-34	323	21	3	3	NUM
admet-34	323	22	)	)	PUNCT
admet-34	323	23	t(h	t(h	ADJ
admet-34	323	24	)	)	PUNCT
admet-34	323	25	amorphous	amorphous	ADJ
admet-34	323	26	crystalline	crystalline	NOUN
admet-34	323	27	a	a	DET
admet-34	323	28	figure	figure	NOUN
admet-34	323	29	4	4	NUM
admet-34	323	30	.	.	PUNCT
admet-34	324	1	(	(	PUNCT
admet-34	324	2	a	a	X
admet-34	324	3	)	)	PUNCT
admet-34	324	4	nimesulide	nimesulide	ADP
admet-34	324	5	plasma	plasma	NOUN
admet-34	324	6	concentration	concentration	NOUN
admet-34	325	1	cp	cp	INTJ
admet-34	325	2	referring	refer	VERB
admet-34	325	3	to	to	ADP
admet-34	325	4	amorphous	amorphous	ADJ
admet-34	325	5	(	(	PUNCT
admet-34	325	6	thick	thick	ADJ
admet-34	325	7	line	line	NOUN
admet-34	325	8	)	)	PUNCT
admet-34	325	9	and	and	CCONJ
admet-34	325	10	crystalline	crystalline	NOUN
admet-34	325	11	(	(	PUNCT
admet-34	325	12	thin	thin	ADJ
admet-34	325	13	line	line	NOUN
admet-34	325	14	)	)	PUNCT
admet-34	325	15	drug	drug	NOUN
admet-34	325	16	.	.	PUNCT
admet-34	326	1	open	open	ADJ
admet-34	326	2	circles	circle	NOUN
admet-34	326	3	indicate	indicate	VERB
admet-34	326	4	experimental	experimental	ADJ
admet-34	326	5	data	datum	NOUN
admet-34	326	6	(	(	PUNCT
admet-34	326	7	average	average	NOUN
admet-34	326	8	of	of	ADP
admet-34	326	9	three	three	NUM
admet-34	326	10	subjects	subject	NOUN
admet-34	326	11	;	;	PUNCT
admet-34	326	12	vertical	vertical	ADJ
admet-34	326	13	bars	bar	NOUN
admet-34	326	14	indicate	indicate	VERB
admet-34	326	15	standard	standard	ADJ
admet-34	326	16	error	error	NOUN
admet-34	326	17	)	)	PUNCT
admet-34	326	18	on	on	ADP
admet-34	326	19	which	which	PRON
admet-34	326	20	the	the	DET
admet-34	326	21	model	model	NOUN
admet-34	326	22	was	be	AUX
admet-34	326	23	fit	fit	ADJ
admet-34	326	24	to	to	ADP
admet-34	326	25	(	(	PUNCT
admet-34	326	26	thin	thin	ADJ
admet-34	326	27	line	line	NOUN
admet-34	326	28	)	)	PUNCT
admet-34	326	29	.	.	PUNCT
admet-34	327	1	delivery	delivery	NOUN
admet-34	327	2	systems	system	NOUN
admet-34	327	3	volume	volume	NOUN
admet-34	327	4	is	be	AUX
admet-34	327	5	equal	equal	ADJ
admet-34	327	6	to	to	ADP
admet-34	327	7	1	1	NUM
admet-34	327	8	cm	cm	NUM
admet-34	327	9	3	3	NUM
admet-34	327	10	and	and	CCONJ
admet-34	327	11	dose	dose	NOUN
admet-34	327	12	is	be	AUX
admet-34	327	13	equal	equal	ADJ
admet-34	327	14	to	to	ADP
admet-34	327	15	100	100	NUM
admet-34	327	16	mg	mg	NOUN
admet-34	327	17	.	.	PUNCT
admet-34	328	1	(	(	PUNCT
admet-34	328	2	b	b	X
admet-34	328	3	)	)	PUNCT
admet-34	328	4	nimesulide	nimesulide	ADP
admet-34	328	5	concentration	concentration	NOUN
admet-34	328	6	in	in	ADP
admet-34	328	7	the	the	DET
admet-34	328	8	release	release	NOUN
admet-34	328	9	environment	environment	NOUN
admet-34	328	10	(	(	PUNCT
admet-34	328	11	cr	cr	NOUN
admet-34	328	12	)	)	PUNCT
admet-34	328	13	referring	refer	VERB
admet-34	328	14	to	to	ADP
admet-34	328	15	the	the	DET
admet-34	328	16	two	two	NUM
admet-34	328	17	delivery	delivery	NOUN
admet-34	328	18	systems	system	NOUN
admet-34	328	19	shown	show	VERB
admet-34	328	20	in	in	ADP
admet-34	328	21	(	(	PUNCT
admet-34	328	22	a	a	NOUN
admet-34	328	23	)	)	PUNCT
admet-34	328	24	.	.	PUNCT
admet-34	329	1	the	the	DET
admet-34	329	2	numerical	numerical	ADJ
admet-34	329	3	solution	solution	NOUN
admet-34	329	4	of	of	ADP
admet-34	329	5	the	the	DET
admet-34	329	6	model	model	NOUN
admet-34	329	7	implied	imply	VERB
admet-34	329	8	the	the	DET
admet-34	329	9	subdivision	subdivision	NOUN
admet-34	329	10	of	of	ADP
admet-34	329	11	the	the	DET
admet-34	329	12	particles	particle	NOUN
admet-34	329	13	distribution	distribution	NOUN
admet-34	329	14	in	in	ADP
admet-34	329	15	10	10	NUM
admet-34	329	16	classes	class	NOUN
admet-34	329	17	and	and	CCONJ
admet-34	329	18	15	15	NUM
admet-34	329	19	control	control	NOUN
admet-34	329	20	volumes	volume	NOUN
admet-34	329	21	were	be	AUX
admet-34	329	22	considered	consider	VERB
admet-34	329	23	for	for	ADP
admet-34	329	24	the	the	DET
admet-34	329	25	generic	generic	ADJ
admet-34	329	26	particle	particle	NOUN
admet-34	329	27	of	of	ADP
admet-34	329	28	each	each	DET
admet-34	329	29	class	class	NOUN
admet-34	329	30	.	.	PUNCT
admet-34	330	1	conclusions	conclusion	NOUN
admet-34	330	2	although	although	SCONJ
admet-34	330	3	the	the	DET
admet-34	330	4	problem	problem	NOUN
admet-34	330	5	of	of	ADP
admet-34	330	6	a	a	DET
admet-34	330	7	reliable	reliable	ADJ
admet-34	330	8	prediction	prediction	NOUN
admet-34	330	9	of	of	ADP
admet-34	330	10	drug	drug	NOUN
admet-34	330	11	concentration	concentration	NOUN
admet-34	330	12	in	in	ADP
admet-34	330	13	plasma	plasma	NOUN
admet-34	330	14	following	follow	VERB
admet-34	330	15	oral	oral	ADJ
admet-34	330	16	administration	administration	NOUN
admet-34	330	17	remains	remain	VERB
admet-34	330	18	a	a	DET
admet-34	330	19	challenging	challenging	ADJ
admet-34	330	20	task	task	NOUN
admet-34	330	21	,	,	PUNCT
admet-34	330	22	a	a	DET
admet-34	330	23	considerable	considerable	ADJ
admet-34	330	24	development	development	NOUN
admet-34	330	25	in	in	ADP
admet-34	330	26	this	this	DET
admet-34	330	27	direction	direction	NOUN
admet-34	330	28	is	be	AUX
admet-34	330	29	represented	represent	VERB
admet-34	330	30	by	by	ADP
admet-34	330	31	mathematical	mathematical	ADJ
admet-34	330	32	models	model	NOUN
admet-34	330	33	able	able	ADJ
admet-34	330	34	to	to	PART
admet-34	330	35	simultaneously	simultaneously	ADV
admet-34	330	36	account	account	VERB
admet-34	330	37	for	for	ADP
admet-34	330	38	the	the	DET
admet-34	330	39	in	in	ADP
admet-34	330	40	vivo	vivo	ADJ
admet-34	330	41	drug	drug	NOUN
admet-34	330	42	release	release	NOUN
admet-34	330	43	and	and	CCONJ
admet-34	330	44	the	the	DET
admet-34	330	45	subsequent	subsequent	ADJ
admet-34	330	46	absorption	absorption	NOUN
admet-34	330	47	,	,	PUNCT
admet-34	330	48	distribution	distribution	NOUN
admet-34	330	49	,	,	PUNCT
admet-34	330	50	metabolism	metabolism	NOUN
admet-34	330	51	and	and	CCONJ
admet-34	330	52	elimination	elimination	NOUN
admet-34	330	53	processes	process	NOUN
admet-34	330	54	(	(	PUNCT
admet-34	330	55	adme	adme	NOUN
admet-34	330	56	)	)	PUNCT
admet-34	330	57	.	.	PUNCT
admet-34	331	1	in	in	ADP
admet-34	331	2	this	this	DET
admet-34	331	3	frame	frame	NOUN
admet-34	331	4	,	,	PUNCT
admet-34	331	5	we	we	PRON
admet-34	331	6	built	build	VERB
admet-34	331	7	up	up	ADP
admet-34	331	8	a	a	DET
admet-34	331	9	reasonable	reasonable	ADJ
admet-34	331	10	mathematical	mathematical	ADJ
admet-34	331	11	model	model	NOUN
admet-34	331	12	resulting	result	VERB
admet-34	331	13	from	from	ADP
admet-34	331	14	merging	merge	VERB
admet-34	331	15	a	a	DET
admet-34	331	16	physiologically	physiologically	ADV
admet-34	331	17	oriented	orient	VERB
admet-34	331	18	pk	pk	NOUN
admet-34	331	19	model	model	NOUN
admet-34	331	20	and	and	CCONJ
admet-34	331	21	a	a	DET
admet-34	331	22	delivery	delivery	NOUN
admet-34	331	23	model	model	NOUN
admet-34	331	24	.	.	PUNCT
admet-34	332	1	wherever	wherever	SCONJ
admet-34	332	2	the	the	DET
admet-34	332	3	final	final	ADJ
admet-34	332	4	aim	aim	NOUN
admet-34	332	5	is	be	AUX
admet-34	332	6	to	to	PART
admet-34	332	7	get	get	VERB
admet-34	332	8	a	a	DET
admet-34	332	9	reliable	reliable	NOUN
admet-34	332	10	in	in	ADP
admet-34	332	11	vivo	vivo	ADJ
admet-34	332	12	simulation	simulation	NOUN
admet-34	332	13	,	,	PUNCT
admet-34	332	14	at	at	ADP
admet-34	332	15	present	present	ADJ
admet-34	332	16	,	,	PUNCT
admet-34	332	17	we	we	PRON
admet-34	332	18	set	set	VERB
admet-34	332	19	up	up	ADP
admet-34	332	20	a	a	DET
admet-34	332	21	theoretical	theoretical	ADJ
admet-34	332	22	tool	tool	NOUN
admet-34	332	23	that	that	PRON
admet-34	332	24	enables	enable	VERB
admet-34	332	25	to	to	PART
admet-34	332	26	rationally	rationally	ADV
admet-34	332	27	compare	compare	VERB
admet-34	332	28	either	either	CCONJ
admet-34	332	29	different	different	ADJ
admet-34	332	30	formulations	formulation	NOUN
admet-34	332	31	of	of	ADP
admet-34	332	32	the	the	DET
admet-34	332	33	same	same	ADJ
admet-34	332	34	drug	drug	NOUN
admet-34	332	35	or	or	CCONJ
admet-34	332	36	the	the	DET
admet-34	332	37	same	same	ADJ
admet-34	332	38	formulation	formulation	NOUN
admet-34	332	39	for	for	ADP
admet-34	332	40	different	different	ADJ
admet-34	332	41	drugs	drug	NOUN
admet-34	332	42	.	.	PUNCT
admet-34	333	1	indeed	indeed	ADV
admet-34	333	2	,	,	PUNCT
admet-34	333	3	our	our	PRON
admet-34	333	4	model	model	NOUN
admet-34	333	5	allows	allow	VERB
admet-34	333	6	the	the	DET
admet-34	333	7	evaluation	evaluation	NOUN
admet-34	333	8	of	of	ADP
admet-34	333	9	the	the	DET
admet-34	333	10	effect	effect	NOUN
admet-34	333	11	of	of	ADP
admet-34	333	12	different	different	ADJ
admet-34	333	13	doses	dose	NOUN
admet-34	333	14	,	,	PUNCT
admet-34	333	15	different	different	ADJ
admet-34	333	16	mean	mean	NOUN
admet-34	333	17	particles	particle	NOUN
admet-34	333	18	size	size	NOUN
admet-34	333	19	and	and	CCONJ
admet-34	333	20	particle	particle	NOUN
admet-34	333	21	sizes	size	NOUN
admet-34	333	22	distribution	distribution	NOUN
admet-34	333	23	,	,	PUNCT
admet-34	333	24	and	and	CCONJ
admet-34	333	25	the	the	DET
admet-34	333	26	drug	drug	NOUN
admet-34	333	27	solid	solid	ADJ
admet-34	333	28	states	state	NOUN
admet-34	333	29	,	,	PUNCT
admet-34	333	30	i.e.	i.e.	X
admet-34	333	31	amorphous	amorphous	ADJ
admet-34	333	32	,	,	PUNCT
admet-34	333	33	nano	nano	NOUN
admet-34	333	34	-	-	PUNCT
admet-34	333	35	crystalline	crystalline	NOUN
admet-34	333	36	and	and	CCONJ
admet-34	333	37	macro	macro	ADJ
admet-34	333	38	-	-	ADJ
admet-34	333	39	crystalline	crystalline	ADJ
admet-34	333	40	drug	drug	NOUN
admet-34	333	41	.	.	PUNCT
admet-34	334	1	according	accord	VERB
admet-34	334	2	to	to	ADP
admet-34	334	3	us	we	PRON
admet-34	334	4	,	,	PUNCT
admet-34	334	5	our	our	PRON
admet-34	334	6	model	model	NOUN
admet-34	334	7	demonstrates	demonstrate	VERB
admet-34	334	8	that	that	SCONJ
admet-34	334	9	in	in	ADP
admet-34	334	10	vivo	vivo	ADJ
admet-34	334	11	release	release	NOUN
admet-34	334	12	kinetics	kinetic	NOUN
admet-34	334	13	can	can	AUX
admet-34	334	14	be	be	AUX
admet-34	334	15	different	different	ADJ
admet-34	334	16	from	from	ADP
admet-34	334	17	the	the	DET
admet-34	334	18	in	in	NOUN
admet-34	334	19	vitro	vitro	X
admet-34	334	20	one	one	NUM
admet-34	334	21	due	due	ADP
admet-34	334	22	to	to	ADP
admet-34	334	23	the	the	DET
admet-34	334	24	effect	effect	NOUN
admet-34	334	25	of	of	ADP
admet-34	334	26	living	live	VERB
admet-34	334	27	tissues	tissue	NOUN
admet-34	334	28	.	.	PUNCT
admet-34	335	1	in	in	ADP
admet-34	335	2	other	other	ADJ
admet-34	335	3	words	word	NOUN
admet-34	335	4	,	,	PUNCT
admet-34	335	5	while	while	SCONJ
admet-34	335	6	the	the	DET
admet-34	335	7	mutual	mutual	ADJ
admet-34	335	8	effect	effect	NOUN
admet-34	335	9	between	between	ADP
admet-34	335	10	drug	drug	NOUN
admet-34	335	11	release	release	NOUN
admet-34	335	12	and	and	CCONJ
admet-34	335	13	adme	adme	NOUN
admet-34	335	14	processes	process	NOUN
admet-34	335	15	is	be	AUX
admet-34	335	16	well	well	ADV
admet-34	335	17	known	know	VERB
admet-34	335	18	,	,	PUNCT
admet-34	335	19	this	this	DET
admet-34	335	20	paper	paper	NOUN
admet-34	335	21	represents	represent	VERB
admet-34	335	22	one	one	NUM
admet-34	335	23	of	of	ADP
admet-34	335	24	the	the	DET
admet-34	335	25	first	first	ADJ
admet-34	335	26	attempts	attempt	NOUN
admet-34	335	27	of	of	ADP
admet-34	335	28	clearly	clearly	ADV
admet-34	335	29	evaluating	evaluate	VERB
admet-34	335	30	and	and	CCONJ
admet-34	335	31	quantifying	quantify	VERB
admet-34	335	32	it	it	PRON
admet-34	335	33	.	.	PUNCT
admet-34	336	1	in	in	ADP
admet-34	336	2	conclusion	conclusion	NOUN
admet-34	336	3	,	,	PUNCT
admet-34	336	4	our	our	PRON
admet-34	336	5	model	model	NOUN
admet-34	336	6	represents	represent	VERB
admet-34	336	7	a	a	DET
admet-34	336	8	rational	rational	ADJ
admet-34	336	9	tool	tool	NOUN
admet-34	336	10	for	for	ADP
admet-34	336	11	the	the	DET
admet-34	336	12	designing	designing	NOUN
admet-34	336	13	of	of	ADP
admet-34	336	14	modern	modern	ADJ
admet-34	336	15	delivery	delivery	NOUN
admet-34	336	16	systems	system	NOUN
admet-34	336	17	and	and	CCONJ
admet-34	336	18	it	it	PRON
admet-34	336	19	should	should	AUX
admet-34	336	20	constitute	constitute	VERB
admet-34	336	21	an	an	DET
admet-34	336	22	important	important	ADJ
admet-34	336	23	step	step	NOUN
admet-34	336	24	on	on	ADP
admet-34	336	25	the	the	DET
admet-34	336	26	way	way	NOUN
admet-34	336	27	to	to	PART
admet-34	336	28	reliable	reliable	ADJ
admet-34	336	29	simulation	simulation	NOUN
admet-34	336	30	of	of	ADP
admet-34	336	31	plasma	plasma	NOUN
admet-34	336	32	drug	drug	NOUN
admet-34	336	33	concentration	concentration	NOUN
admet-34	336	34	following	follow	VERB
admet-34	336	35	oral	oral	ADJ
admet-34	336	36	administration	administration	NOUN
admet-34	336	37	.	.	PUNCT
admet-34	337	1	acknowledgements	acknowledgement	NOUN
admet-34	337	2	:	:	PUNCT
admet-34	337	3	financial	financial	ADJ
admet-34	337	4	support	support	NOUN
admet-34	337	5	from	from	ADP
admet-34	337	6	the	the	DET
admet-34	337	7	italian	italian	ADJ
admet-34	337	8	ministry	ministry	PROPN
admet-34	337	9	of	of	ADP
admet-34	337	10	education	education	PROPN
admet-34	337	11	fund	fund	PROPN
admet-34	337	12	“	"	PUNCT
admet-34	337	13	prin	prin	NOUN
admet-34	337	14	2010	2010	NUM
admet-34	337	15	-	-	SYM
admet-34	337	16	2011	2011	NUM
admet-34	337	17	(	(	PUNCT
admet-34	337	18	20109plmh2	20109plmh2	NUM
admet-34	337	19	)	)	PUNCT
admet-34	337	20	”	"	PUNCT
admet-34	337	21	is	be	AUX
admet-34	337	22	acknowledged	acknowledge	VERB
admet-34	337	23	.	.	PUNCT
admet-34	338	1	del	del	PROPN
admet-34	338	2	cont	cont	PROPN
admet-34	338	3	et	et	PROPN
admet-34	338	4	al	al	PROPN
admet-34	338	5	.	.	PROPN
admet-34	338	6	admet	admet	PROPN
admet-34	338	7	&	&	CCONJ
admet-34	338	8	dmpk	dmpk	PROPN
admet-34	338	9	2(2	2(2	NUM
admet-34	338	10	)	)	PUNCT
admet-34	338	11	(	(	PUNCT
admet-34	338	12	2014	2014	NUM
admet-34	338	13	)	)	PUNCT
admet-34	338	14	80	80	NUM
admet-34	338	15	-	-	SYM
admet-34	338	16	97	97	NUM
admet-34	338	17	94	94	NUM
admet-34	338	18	references	reference	NOUN
admet-34	338	19	[	[	X
admet-34	338	20	1	1	NUM
admet-34	338	21	]	]	PUNCT
admet-34	338	22	p.	p.	NOUN
admet-34	338	23	poulin	poulin	PROPN
admet-34	338	24	,	,	PUNCT
admet-34	338	25	h.m	h.m	PROPN
admet-34	338	26	.	.	PROPN
admet-34	338	27	jones	jones	PROPN
admet-34	338	28	,	,	PUNCT
admet-34	338	29	r.d	r.d	PROPN
admet-34	338	30	.	.	PROPN
admet-34	338	31	jones	jones	PROPN
admet-34	338	32	,	,	PUNCT
admet-34	338	33	j.w.t	j.w.t	PROPN
admet-34	338	34	.	.	PUNCT
admet-34	339	1	yates	yates	PROPN
admet-34	339	2	,	,	PUNCT
admet-34	339	3	c.r	c.r	PROPN
admet-34	339	4	.	.	PROPN
admet-34	339	5	gibson	gibson	PROPN
admet-34	339	6	,	,	PUNCT
admet-34	339	7	j.y	j.y	PROPN
admet-34	339	8	.	.	PROPN
admet-34	339	9	chien	chien	PROPN
admet-34	339	10	,	,	PUNCT
admet-34	339	11	b.j	b.j	PROPN
admet-34	339	12	.	.	PROPN
admet-34	339	13	ring	ring	PROPN
admet-34	339	14	,	,	PUNCT
admet-34	339	15	k.k	k.k	PROPN
admet-34	339	16	.	.	PROPN
admet-34	339	17	adkison	adkison	PROPN
admet-34	339	18	,	,	PUNCT
admet-34	339	19	h.	h.	PROPN
admet-34	339	20	he	he	PROPN
admet-34	339	21	,	,	PUNCT
admet-34	339	22	r.	r.	PROPN
admet-34	339	23	vuppugalla	vuppugalla	PROPN
admet-34	339	24	,	,	PUNCT
admet-34	339	25	p.	p.	NOUN
admet-34	339	26	marathe	marathe	NOUN
admet-34	339	27	,	,	PUNCT
admet-34	339	28	v.	v.	PROPN
admet-34	339	29	fischer	fischer	PROPN
admet-34	339	30	,	,	PUNCT
admet-34	339	31	s.	s.	PROPN
admet-34	339	32	dutta	dutta	PROPN
admet-34	339	33	,	,	PUNCT
admet-34	339	34	v.k	v.k	PROPN
admet-34	339	35	.	.	PROPN
admet-34	339	36	sinha	sinha	PROPN
admet-34	339	37	,	,	PUNCT
admet-34	339	38	t.	t.	PROPN
admet-34	339	39	björnsson	björnsson	PROPN
admet-34	339	40	,	,	PUNCT
admet-34	339	41	t.	t.	PROPN
admet-34	339	42	lavé	lavé	PROPN
admet-34	339	43	,	,	PUNCT
admet-34	339	44	m.s	m.s	PROPN
admet-34	339	45	.	.	PROPN
admet-34	339	46	ku	ku	PROPN
admet-34	339	47	,	,	PUNCT
admet-34	339	48	journal	journal	PROPN
admet-34	339	49	of	of	ADP
admet-34	339	50	pharmaceutical	pharmaceutical	PROPN
admet-34	339	51	sciences	science	NOUN
admet-34	339	52	100	100	NUM
admet-34	339	53	(	(	PUNCT
admet-34	339	54	2011	2011	NUM
admet-34	339	55	)	)	PUNCT
admet-34	339	56	4051	4051	NUM
admet-34	339	57	–	–	PUNCT
admet-34	339	58	4073	4073	NUM
admet-34	339	59	.	.	PUNCT
admet-34	340	1	[	[	X
admet-34	340	2	2	2	X
admet-34	340	3	]	]	X
admet-34	340	4	r.d	r.d	PROPN
admet-34	340	5	.	.	PROPN
admet-34	340	6	jones	jones	PROPN
admet-34	340	7	,	,	PUNCT
admet-34	340	8	h.m	h.m	PROPN
admet-34	340	9	.	.	PROPN
admet-34	340	10	jones	jones	PROPN
admet-34	340	11	,	,	PUNCT
admet-34	340	12	m.	m.	PROPN
admet-34	340	13	rowland	rowland	PROPN
admet-34	340	14	,	,	PUNCT
admet-34	340	15	c.r	c.r	PROPN
admet-34	340	16	.	.	PROPN
admet-34	340	17	gibson	gibson	PROPN
admet-34	340	18	,	,	PUNCT
admet-34	340	19	j.w.t	j.w.t	PROPN
admet-34	340	20	.	.	PUNCT
admet-34	340	21	yates	yates	PROPN
admet-34	340	22	,	,	PUNCT
admet-34	340	23	j.y	j.y	PROPN
admet-34	340	24	.	.	PROPN
admet-34	340	25	chien	chien	PROPN
admet-34	340	26	,	,	PUNCT
admet-34	340	27	b.j	b.j	PROPN
admet-34	340	28	.	.	PROPN
admet-34	340	29	ring	ring	PROPN
admet-34	340	30	,	,	PUNCT
admet-34	340	31	k.k	k.k	PROPN
admet-34	340	32	.	.	PROPN
admet-34	340	33	adkison	adkison	PROPN
admet-34	340	34	,	,	PUNCT
admet-34	340	35	m.s	m.s	PROPN
admet-34	340	36	.	.	PROPN
admet-34	340	37	ku	ku	PROPN
admet-34	340	38	,	,	PUNCT
admet-34	340	39	h.	h.	PROPN
admet-34	340	40	he	he	PROPN
admet-34	340	41	,	,	PUNCT
admet-34	340	42	r.	r.	PROPN
admet-34	340	43	vuppugalla	vuppugalla	PROPN
admet-34	340	44	,	,	PUNCT
admet-34	340	45	p.	p.	NOUN
admet-34	340	46	marathe	marathe	NOUN
admet-34	340	47	,	,	PUNCT
admet-34	340	48	v.	v.	PROPN
admet-34	340	49	fischer	fischer	PROPN
admet-34	340	50	,	,	PUNCT
admet-34	340	51	s.	s.	PROPN
admet-34	340	52	dutta	dutta	PROPN
admet-34	340	53	,	,	PUNCT
admet-34	340	54	v.k	v.k	PROPN
admet-34	340	55	.	.	PROPN
admet-34	340	56	sinha	sinha	PROPN
admet-34	340	57	,	,	PUNCT
admet-34	340	58	t.	t.	PROPN
admet-34	340	59	björnsson	björnsson	PROPN
admet-34	340	60	,	,	PUNCT
admet-34	340	61	t.	t.	PROPN
admet-34	340	62	lavé	lavé	NOUN
admet-34	340	63	,	,	PUNCT
admet-34	340	64	p.	p.	PROPN
admet-34	340	65	poulin	poulin	PROPN
admet-34	340	66	,	,	PUNCT
admet-34	340	67	journal	journal	NOUN
admet-34	340	68	of	of	ADP
admet-34	340	69	pharmaceutical	pharmaceutical	PROPN
admet-34	340	70	sciences	science	NOUN
admet-34	340	71	100	100	NUM
admet-34	340	72	(	(	PUNCT
admet-34	340	73	2011	2011	NUM
admet-34	340	74	)	)	PUNCT
admet-34	340	75	4074	4074	NUM
admet-34	340	76	–	–	PUNCT
admet-34	340	77	4089	4089	NUM
admet-34	340	78	.	.	PUNCT
admet-34	341	1	[	[	X
admet-34	341	2	3	3	X
admet-34	341	3	]	]	X
admet-34	341	4	b.j	b.j	PROPN
admet-34	341	5	.	.	PROPN
admet-34	341	6	ring	ring	NOUN
admet-34	341	7	,	,	PUNCT
admet-34	341	8	j.y	j.y	PROPN
admet-34	341	9	.	.	PROPN
admet-34	341	10	chien	chien	PROPN
admet-34	341	11	,	,	PUNCT
admet-34	341	12	k.k	k.k	PROPN
admet-34	341	13	.	.	PROPN
admet-34	341	14	adkison	adkison	PROPN
admet-34	341	15	,	,	PUNCT
admet-34	341	16	h.m	h.m	PROPN
admet-34	341	17	.	.	PROPN
admet-34	341	18	jones	jones	PROPN
admet-34	341	19	,	,	PUNCT
admet-34	341	20	m.	m.	PROPN
admet-34	341	21	rowland	rowland	PROPN
admet-34	341	22	,	,	PUNCT
admet-34	341	23	r.d	r.d	PROPN
admet-34	341	24	.	.	PROPN
admet-34	341	25	jones	jones	PROPN
admet-34	341	26	,	,	PUNCT
admet-34	341	27	j.w.t	j.w.t	PROPN
admet-34	341	28	.	.	PUNCT
admet-34	342	1	yates	yates	PROPN
admet-34	342	2	,	,	PUNCT
admet-34	342	3	m.s	m.s	PROPN
admet-34	342	4	.	.	PROPN
admet-34	342	5	ku	ku	PROPN
admet-34	342	6	,	,	PUNCT
admet-34	342	7	c.r	c.r	PROPN
admet-34	342	8	.	.	PROPN
admet-34	342	9	gibson	gibson	PROPN
admet-34	342	10	,	,	PUNCT
admet-34	342	11	h.	h.	PROPN
admet-34	342	12	he	he	PROPN
admet-34	342	13	,	,	PUNCT
admet-34	342	14	r.	r.	PROPN
admet-34	342	15	vuppugalla	vuppugalla	PROPN
admet-34	342	16	,	,	PUNCT
admet-34	342	17	p.	p.	NOUN
admet-34	342	18	marathe	marathe	NOUN
admet-34	342	19	,	,	PUNCT
admet-34	342	20	v.	v.	PROPN
admet-34	342	21	fischer	fischer	PROPN
admet-34	342	22	,	,	PUNCT
admet-34	342	23	s.	s.	PROPN
admet-34	342	24	dutta	dutta	PROPN
admet-34	342	25	,	,	PUNCT
admet-34	342	26	v.k	v.k	PROPN
admet-34	342	27	.	.	PROPN
admet-34	342	28	sinha	sinha	PROPN
admet-34	342	29	,	,	PUNCT
admet-34	342	30	t.	t.	PROPN
admet-34	342	31	björnsson	björnsson	PROPN
admet-34	342	32	,	,	PUNCT
admet-34	342	33	t.	t.	PROPN
admet-34	342	34	lavé	lavé	NOUN
admet-34	342	35	,	,	PUNCT
admet-34	342	36	p.	p.	PROPN
admet-34	342	37	poulin	poulin	PROPN
admet-34	342	38	,	,	PUNCT
admet-34	342	39	journal	journal	NOUN
admet-34	342	40	of	of	ADP
admet-34	342	41	pharmaceutical	pharmaceutical	PROPN
admet-34	342	42	sciences	science	NOUN
admet-34	342	43	100	100	NUM
admet-34	342	44	(	(	PUNCT
admet-34	342	45	2011	2011	NUM
admet-34	342	46	)	)	PUNCT
admet-34	342	47	4090	4090	NUM
admet-34	342	48	–	–	PUNCT
admet-34	342	49	4110	4110	NUM
admet-34	342	50	.	.	PUNCT
admet-34	343	1	[	[	X
admet-34	343	2	4	4	NUM
admet-34	343	3	]	]	PUNCT
admet-34	343	4	r.	r.	NOUN
admet-34	343	5	vuppugalla	vuppugalla	NOUN
admet-34	343	6	,	,	PUNCT
admet-34	343	7	p.	p.	NOUN
admet-34	343	8	marathe	marathe	PROPN
admet-34	343	9	,	,	PUNCT
admet-34	343	10	h.	h.	PROPN
admet-34	343	11	he	he	PRON
admet-34	343	12	,	,	PUNCT
admet-34	343	13	r.d	r.d	PROPN
admet-34	343	14	.	.	PROPN
admet-34	343	15	jones	jones	PROPN
admet-34	343	16	,	,	PUNCT
admet-34	343	17	j.w.t	j.w.t	PROPN
admet-34	343	18	.	.	PUNCT
admet-34	344	1	yates	yates	PROPN
admet-34	344	2	,	,	PUNCT
admet-34	344	3	h.m	h.m	PROPN
admet-34	344	4	.	.	PROPN
admet-34	344	5	jones	jones	PROPN
admet-34	344	6	,	,	PUNCT
admet-34	344	7	c.r	c.r	PROPN
admet-34	344	8	.	.	PROPN
admet-34	344	9	gibson	gibson	PROPN
admet-34	344	10	,	,	PUNCT
admet-34	344	11	j.y	j.y	PROPN
admet-34	344	12	.	.	PROPN
admet-34	344	13	chien	chien	PROPN
admet-34	344	14	,	,	PUNCT
admet-34	344	15	b.j	b.j	PROPN
admet-34	344	16	.	.	PROPN
admet-34	344	17	ring	ring	PROPN
admet-34	344	18	,	,	PUNCT
admet-34	344	19	k.k	k.k	PROPN
admet-34	344	20	.	.	PROPN
admet-34	344	21	adkison	adkison	PROPN
admet-34	344	22	,	,	PUNCT
admet-34	344	23	m.s	m.s	PROPN
admet-34	344	24	.	.	PROPN
admet-34	344	25	ku	ku	PROPN
admet-34	344	26	,	,	PUNCT
admet-34	344	27	v.	v.	PROPN
admet-34	344	28	fischer	fischer	PROPN
admet-34	344	29	,	,	PUNCT
admet-34	344	30	s.	s.	PROPN
admet-34	344	31	dutta	dutta	PROPN
admet-34	344	32	,	,	PUNCT
admet-34	344	33	v.k	v.k	PROPN
admet-34	344	34	.	.	PROPN
admet-34	344	35	sinha	sinha	PROPN
admet-34	344	36	,	,	PUNCT
admet-34	344	37	t.	t.	PROPN
admet-34	344	38	björnsson	björnsson	PROPN
admet-34	344	39	,	,	PUNCT
admet-34	344	40	t.	t.	PROPN
admet-34	344	41	lavé	lavé	NOUN
admet-34	344	42	,	,	PUNCT
admet-34	344	43	p.	p.	PROPN
admet-34	344	44	poulin	poulin	PROPN
admet-34	344	45	,	,	PUNCT
admet-34	344	46	journal	journal	NOUN
admet-34	344	47	of	of	ADP
admet-34	344	48	pharmaceutical	pharmaceutical	PROPN
admet-34	344	49	sciences	science	NOUN
admet-34	344	50	100	100	NUM
admet-34	344	51	(	(	PUNCT
admet-34	344	52	2011	2011	NUM
admet-34	344	53	)	)	PUNCT
admet-34	344	54	4111	4111	NUM
admet-34	344	55	–	–	PUNCT
admet-34	344	56	4126	4126	NUM
admet-34	344	57	.	.	PUNCT
admet-34	345	1	[	[	X
admet-34	345	2	5	5	NUM
admet-34	345	3	]	]	PUNCT
admet-34	345	4	p.	p.	NOUN
admet-34	345	5	poulin	poulin	PROPN
admet-34	345	6	,	,	PUNCT
admet-34	345	7	h.m	h.m	PROPN
admet-34	345	8	.	.	PROPN
admet-34	345	9	jones	jones	PROPN
admet-34	345	10	,	,	PUNCT
admet-34	345	11	r.d	r.d	PROPN
admet-34	345	12	.	.	PROPN
admet-34	345	13	jones	jones	PROPN
admet-34	345	14	,	,	PUNCT
admet-34	345	15	j.w.t	j.w.t	PROPN
admet-34	345	16	.	.	PUNCT
admet-34	346	1	yates	yates	PROPN
admet-34	346	2	,	,	PUNCT
admet-34	346	3	c.r	c.r	PROPN
admet-34	346	4	.	.	PROPN
admet-34	346	5	gibson	gibson	PROPN
admet-34	346	6	,	,	PUNCT
admet-34	346	7	m.	m.	NOUN
admet-34	346	8	rowland	rowland	PROPN
admet-34	346	9	,	,	PUNCT
admet-34	346	10	j.y	j.y	PROPN
admet-34	346	11	.	.	PROPN
admet-34	346	12	chien	chien	PROPN
admet-34	346	13	,	,	PUNCT
admet-34	346	14	b.j	b.j	PROPN
admet-34	346	15	.	.	PROPN
admet-34	346	16	ring	ring	PROPN
admet-34	346	17	,	,	PUNCT
admet-34	346	18	k.k	k.k	PROPN
admet-34	346	19	.	.	PROPN
admet-34	346	20	adkison	adkison	PROPN
admet-34	346	21	,	,	PUNCT
admet-34	346	22	m.s	m.s	PROPN
admet-34	346	23	.	.	PROPN
admet-34	346	24	ku	ku	PROPN
admet-34	346	25	,	,	PUNCT
admet-34	346	26	h.	h.	PROPN
admet-34	346	27	he	he	PROPN
admet-34	346	28	,	,	PUNCT
admet-34	346	29	r.	r.	PROPN
admet-34	346	30	vuppugalla	vuppugalla	PROPN
admet-34	346	31	,	,	PUNCT
admet-34	346	32	p.	p.	NOUN
admet-34	346	33	marathe	marathe	NOUN
admet-34	346	34	,	,	PUNCT
admet-34	346	35	v.	v.	PROPN
admet-34	346	36	fischer	fischer	PROPN
admet-34	346	37	,	,	PUNCT
admet-34	346	38	s.	s.	PROPN
admet-34	346	39	dutta	dutta	PROPN
admet-34	346	40	,	,	PUNCT
admet-34	346	41	v.k	v.k	PROPN
admet-34	346	42	.	.	PROPN
admet-34	346	43	sinha	sinha	PROPN
admet-34	346	44	,	,	PUNCT
admet-34	346	45	t.	t.	PROPN
admet-34	346	46	björnsson	björnsson	PROPN
admet-34	346	47	,	,	PUNCT
admet-34	346	48	t.	t.	PROPN
admet-34	346	49	lavé	lavé	PROPN
admet-34	346	50	,	,	PUNCT
admet-34	346	51	j.w	j.w	PROPN
admet-34	346	52	.	.	PUNCT
admet-34	346	53	t.	t.	PROPN
admet-34	346	54	yates	yates	PROPN
admet-34	346	55	,	,	PUNCT
admet-34	346	56	journal	journal	NOUN
admet-34	346	57	of	of	ADP
admet-34	346	58	pharmaceutical	pharmaceutical	PROPN
admet-34	346	59	sciences	science	NOUN
admet-34	346	60	100	100	NUM
admet-34	346	61	(	(	PUNCT
admet-34	346	62	2011	2011	NUM
admet-34	346	63	)	)	PUNCT
admet-34	346	64	4127	4127	NUM
admet-34	346	65	–	–	PUNCT
admet-34	346	66	4157	4157	NUM
admet-34	346	67	.	.	PUNCT
admet-34	347	1	[	[	X
admet-34	347	2	6	6	NUM
admet-34	347	3	]	]	PUNCT
admet-34	347	4	b.	b.	PROPN
admet-34	347	5	agoram	agoram	PROPN
admet-34	347	6	,	,	PUNCT
admet-34	347	7	w.s	w.s	PROPN
admet-34	347	8	.	.	PROPN
admet-34	347	9	woltosz	woltosz	PROPN
admet-34	347	10	,	,	PUNCT
admet-34	347	11	m.b	m.b	PROPN
admet-34	347	12	.	.	PROPN
admet-34	347	13	bolger	bolger	PROPN
admet-34	347	14	,	,	PUNCT
admet-34	347	15	advanced	advanced	ADJ
admet-34	347	16	drug	drug	NOUN
admet-34	347	17	delivery	delivery	NOUN
admet-34	347	18	reviews	review	VERB
admet-34	347	19	50	50	NUM
admet-34	347	20	suppl	suppl	ADJ
admet-34	347	21	1	1	NUM
admet-34	347	22	(	(	PUNCT
admet-34	347	23	2001	2001	NUM
admet-34	347	24	)	)	PUNCT
admet-34	347	25	s41	s41	NOUN
admet-34	347	26	–	–	PUNCT
admet-34	347	27	67	67	NUM
admet-34	347	28	.	.	PUNCT
admet-34	348	1	[	[	X
admet-34	348	2	7	7	X
admet-34	348	3	]	]	X
admet-34	348	4	j.	j.	PROPN
admet-34	348	5	siepmann	siepmann	PROPN
admet-34	348	6	,	,	PUNCT
admet-34	348	7	f.	f.	PROPN
admet-34	348	8	siepmann	siepmann	PROPN
admet-34	348	9	,	,	PUNCT
admet-34	348	10	f.	f.	PROPN
admet-34	348	11	international	international	PROPN
admet-34	348	12	journal	journal	PROPN
admet-34	348	13	of	of	ADP
admet-34	348	14	pharmaceutics	pharmaceutic	NOUN
admet-34	348	15	314	314	NUM
admet-34	348	16	(	(	PUNCT
admet-34	348	17	2008	2008	NUM
admet-34	348	18	)	)	PUNCT
admet-34	348	19	101–119	101–119	NUM
admet-34	348	20	.	.	PUNCT
admet-34	349	1	[	[	X
admet-34	349	2	8	8	NUM
admet-34	349	3	]	]	PUNCT
admet-34	349	4	m.	m.	NOUN
admet-34	349	5	grassi	grassi	PROPN
admet-34	349	6	,	,	PUNCT
admet-34	349	7	g.	g.	PROPN
admet-34	349	8	lamberti	lamberti	PROPN
admet-34	349	9	,	,	PUNCT
admet-34	349	10	s.	s.	PROPN
admet-34	349	11	cascone	cascone	PROPN
admet-34	349	12	,	,	PUNCT
admet-34	349	13	g.	g.	PROPN
admet-34	349	14	grassi	grassi	PROPN
admet-34	349	15	.	.	PUNCT
admet-34	350	1	international	international	ADJ
admet-34	350	2	journal	journal	PROPN
admet-34	350	3	of	of	ADP
admet-34	350	4	pharmaceutics	pharmaceutic	NOUN
admet-34	350	5	418	418	NUM
admet-34	350	6	(	(	PUNCT
admet-34	350	7	2011	2011	NUM
admet-34	350	8	)	)	PUNCT
admet-34	350	9	130–141	130–141	NUM
admet-34	350	10	.	.	PUNCT
admet-34	351	1	[	[	X
admet-34	351	2	9	9	NUM
admet-34	351	3	]	]	X
admet-34	351	4	d.	d.	PROPN
admet-34	351	5	evans	evans	PROPN
admet-34	351	6	,	,	PUNCT
admet-34	351	7	2010	2010	NUM
admet-34	351	8	.	.	PUNCT
admet-34	352	1	scientia	scientia	PROPN
admet-34	352	2	pharmaceutica	pharmaceutica	PROPN
admet-34	352	3	78	78	NUM
admet-34	352	4	(	(	PUNCT
admet-34	352	5	2010	2010	NUM
admet-34	352	6	)	)	PUNCT
admet-34	352	7	588	588	NUM
admet-34	352	8	–	–	PUNCT
admet-34	352	9	588	588	NUM
admet-34	352	10	.	.	PUNCT
admet-34	353	1	[	[	X
admet-34	353	2	10	10	NUM
admet-34	353	3	]	]	PUNCT
admet-34	353	4	m.	m.	NOUN
admet-34	353	5	di	di	PROPN
admet-34	353	6	muria	muria	PROPN
admet-34	353	7	,	,	PUNCT
admet-34	353	8	g.	g.	PROPN
admet-34	353	9	lamberti	lamberti	PROPN
admet-34	353	10	,	,	PUNCT
admet-34	353	11	g.	g.	PROPN
admet-34	353	12	titomanlio	titomanlio	PROPN
admet-34	353	13	,	,	PUNCT
admet-34	353	14	iec	iec	PROPN
admet-34	353	15	research	research	NOUN
admet-34	353	16	49	49	NUM
admet-34	353	17	(	(	PUNCT
admet-34	353	18	2010	2010	NUM
admet-34	353	19	)	)	PUNCT
admet-34	353	20	2969	2969	NUM
admet-34	353	21	–	–	PUNCT
admet-34	353	22	2978	2978	NUM
admet-34	353	23	.	.	PUNCT
admet-34	354	1	[	[	X
admet-34	354	2	11	11	NUM
admet-34	354	3	]	]	PUNCT
admet-34	354	4	m.	m.	NOUN
admet-34	354	5	grassi	grassi	PROPN
admet-34	354	6	,	,	PUNCT
admet-34	354	7	i.	i.	PROPN
admet-34	354	8	colombo	colombo	PROPN
admet-34	354	9	,	,	PUNCT
admet-34	354	10	r.	r.	PROPN
admet-34	354	11	lapasin	lapasin	PROPN
admet-34	354	12	,	,	PUNCT
admet-34	354	13	journal	journal	NOUN
admet-34	354	14	of	of	ADP
admet-34	354	15	controlled	control	VERB
admet-34	354	16	release	release	NOUN
admet-34	354	17	68	68	NUM
admet-34	354	18	(	(	PUNCT
admet-34	354	19	2000	2000	NUM
admet-34	354	20	)	)	PUNCT
admet-34	354	21	97–113	97–113	NUM
admet-34	354	22	.	.	PUNCT
admet-34	355	1	[	[	X
admet-34	355	2	12	12	NUM
admet-34	355	3	]	]	X
admet-34	355	4	g.	g.	PROPN
admet-34	355	5	grassi	grassi	PROPN
admet-34	355	6	,	,	PUNCT
admet-34	355	7	d.	d.	PROPN
admet-34	355	8	hasa	hasa	PROPN
admet-34	355	9	,	,	PUNCT
admet-34	355	10	d.	d.	PROPN
admet-34	355	11	voinovich	voinovich	PROPN
admet-34	355	12	,	,	PUNCT
admet-34	355	13	b.	b.	PROPN
admet-34	355	14	perissutti	perissutti	PROPN
admet-34	355	15	,	,	PUNCT
admet-34	355	16	b.	b.	PROPN
admet-34	355	17	dapas	dapas	PROPN
admet-34	355	18	,	,	PUNCT
admet-34	355	19	r.	r.	PROPN
admet-34	355	20	farra	farra	PROPN
admet-34	355	21	,	,	PUNCT
admet-34	355	22	e.	e.	PROPN
admet-34	355	23	franceschinis	franceschinis	PROPN
admet-34	355	24	,	,	PUNCT
admet-34	355	25	m.	m.	NOUN
admet-34	355	26	grassi	grassi	PROPN
admet-34	355	27	,	,	PUNCT
admet-34	355	28	molecular	molecular	ADJ
admet-34	355	29	pharmaceutics	pharmaceutic	NOUN
admet-34	355	30	7	7	NUM
admet-34	355	31	,	,	PUNCT
admet-34	355	32	(	(	PUNCT
admet-34	355	33	2010	2010	NUM
admet-34	355	34	)	)	PUNCT
admet-34	355	35	1488	1488	NUM
admet-34	355	36	–	–	PUNCT
admet-34	355	37	1497	1497	NUM
admet-34	355	38	.	.	PUNCT
admet-34	356	1	[	[	X
admet-34	356	2	13	13	NUM
admet-34	356	3	]	]	X
admet-34	356	4	c.	c.	PROPN
admet-34	356	5	tapia	tapia	PROPN
admet-34	356	6	,	,	PUNCT
admet-34	356	7	g.	g.	PROPN
admet-34	356	8	buckton	buckton	PROPN
admet-34	356	9	,	,	PUNCT
admet-34	356	10	j.m	j.m	PROPN
admet-34	356	11	.	.	PROPN
admet-34	356	12	newton	newton	PROPN
admet-34	356	13	,	,	PUNCT
admet-34	356	14	international	international	ADJ
admet-34	356	15	journal	journal	NOUN
admet-34	356	16	of	of	ADP
admet-34	356	17	pharmaceutics	pharmaceutic	NOUN
admet-34	356	18	92	92	NUM
admet-34	356	19	(	(	PUNCT
admet-34	356	20	1993	1993	NUM
admet-34	356	21	)	)	PUNCT
admet-34	356	22	211–218	211–218	NUM
admet-34	356	23	.	.	PUNCT
admet-34	357	1	[	[	X
admet-34	357	2	14	14	NUM
admet-34	357	3	]	]	X
admet-34	357	4	r.	r.	PROPN
admet-34	357	5	jain	jain	PROPN
admet-34	357	6	,	,	PUNCT
admet-34	357	7	l.	l.	PROPN
admet-34	357	8	gerlowski	gerlowski	PROPN
admet-34	357	9	,	,	PUNCT
admet-34	357	10	j.	j.	PROPN
admet-34	357	11	weissbrod	weissbrod	PROPN
admet-34	357	12	,	,	PUNCT
admet-34	357	13	j.	j.	PROPN
admet-34	357	14	wang	wang	PROPN
admet-34	357	15	,	,	PUNCT
admet-34	357	16	r.	r.	PROPN
admet-34	357	17	pierson	pierson	PROPN
admet-34	357	18	,	,	PUNCT
admet-34	357	19	annals	annal	NOUN
admet-34	357	20	of	of	ADP
admet-34	357	21	biomedical	biomedical	ADJ
admet-34	357	22	engineering	engineering	NOUN
admet-34	357	23	9	9	NUM
admet-34	357	24	(	(	PUNCT
admet-34	357	25	1981	1981	NUM
admet-34	357	26	)	)	PUNCT
admet-34	357	27	347	347	NUM
admet-34	357	28	-	-	SYM
admet-34	357	29	361	361	NUM
admet-34	357	30	.	.	PUNCT
admet-34	358	1	[	[	X
admet-34	358	2	15	15	NUM
admet-34	358	3	]	]	X
admet-34	358	4	i.	i.	PROPN
admet-34	358	5	a.	a.	PROPN
admet-34	358	6	nestorov	nestorov	PROPN
admet-34	358	7	,	,	PUNCT
admet-34	358	8	l.	l.	PROPN
admet-34	358	9	j.	j.	PROPN
admet-34	358	10	aarons	aarons	PROPN
admet-34	358	11	,	,	PUNCT
admet-34	358	12	p.	p.	NOUN
admet-34	358	13	a.	a.	PROPN
admet-34	358	14	arundel	arundel	PROPN
admet-34	358	15	,	,	PUNCT
admet-34	358	16	m	m	PROPN
admet-34	358	17	rowland	rowland	PROPN
admet-34	358	18	,	,	PUNCT
admet-34	358	19	journal	journal	NOUN
admet-34	358	20	of	of	ADP
admet-34	358	21	pharmacokinetics	pharmacokinetic	NOUN
admet-34	358	22	and	and	CCONJ
admet-34	358	23	biopharmaceutics	biopharmaceutics	NOUN
admet-34	358	24	26	26	NUM
admet-34	358	25	(	(	PUNCT
admet-34	358	26	1998	1998	NUM
admet-34	358	27	)	)	PUNCT
admet-34	358	28	21	21	NUM
admet-34	358	29	-	-	SYM
admet-34	358	30	46	46	NUM
admet-34	358	31	.	.	PUNCT
admet-34	359	1	[	[	X
admet-34	359	2	16	16	NUM
admet-34	359	3	]	]	PUNCT
admet-34	359	4	m.	m.	NOUN
admet-34	359	5	grassi	grassi	PROPN
admet-34	359	6	,	,	PUNCT
admet-34	359	7	g.	g.	PROPN
admet-34	359	8	grassi	grassi	PROPN
admet-34	359	9	,	,	PUNCT
admet-34	359	10	r.	r.	PROPN
admet-34	359	11	lapasin	lapasin	PROPN
admet-34	359	12	,	,	PUNCT
admet-34	359	13	i.	i.	NOUN
admet-34	359	14	colombo	colombo	PROPN
admet-34	359	15	,	,	PUNCT
admet-34	359	16	understanding	understand	VERB
admet-34	359	17	drug	drug	NOUN
admet-34	359	18	release	release	NOUN
admet-34	359	19	and	and	CCONJ
admet-34	359	20	absorption	absorption	NOUN
admet-34	359	21	mechanisms	mechanism	NOUN
admet-34	359	22	:	:	PUNCT
admet-34	359	23	a	a	DET
admet-34	359	24	physical	physical	ADJ
admet-34	359	25	and	and	CCONJ
admet-34	359	26	mathematical	mathematical	ADJ
admet-34	359	27	approach	approach	NOUN
admet-34	359	28	,	,	PUNCT
admet-34	359	29	crc	crc	NOUN
admet-34	359	30	press	press	PROPN
admet-34	359	31	,	,	PUNCT
admet-34	359	32	boca	boca	PROPN
admet-34	359	33	raton	raton	PROPN
admet-34	359	34	,	,	PUNCT
admet-34	359	35	usa	usa	PROPN
admet-34	359	36	,	,	PUNCT
admet-34	359	37	2006	2006	NUM
admet-34	359	38	.	.	PUNCT
admet-34	360	1	[	[	X
admet-34	360	2	17	17	NUM
admet-34	360	3	]	]	X
admet-34	360	4	g.	g.	PROPN
admet-34	360	5	camera	camera	NOUN
admet-34	360	6	-	-	PUNCT
admet-34	360	7	roda	roda	PROPN
admet-34	360	8	,	,	PUNCT
admet-34	360	9	g.c	g.c	PROPN
admet-34	360	10	.	.	PROPN
admet-34	360	11	sarti	sarti	PROPN
admet-34	360	12	,	,	PUNCT
admet-34	360	13	aiche	aiche	PROPN
admet-34	360	14	journal	journal	PROPN
admet-34	360	15	36	36	NUM
admet-34	360	16	(	(	PUNCT
admet-34	360	17	1990	1990	NUM
admet-34	360	18	)	)	PUNCT
admet-34	360	19	851	851	NUM
admet-34	360	20	–	–	PUNCT
admet-34	360	21	860	860	NUM
admet-34	360	22	.	.	PUNCT
admet-34	361	1	[	[	X
admet-34	361	2	18	18	NUM
admet-34	361	3	]	]	X
admet-34	361	4	n.	n.	NOUN
admet-34	361	5	a.	a.	NOUN
admet-34	361	6	peppas	peppas	PROPN
admet-34	361	7	,	,	PUNCT
admet-34	361	8	c.	c.	PROPN
admet-34	361	9	t	t	PROPN
admet-34	361	10	reinhart	reinhart	PROPN
admet-34	361	11	,	,	PUNCT
admet-34	361	12	journal	journal	NOUN
admet-34	361	13	of	of	ADP
admet-34	361	14	membrane	membrane	NOUN
admet-34	361	15	science	science	NOUN
admet-34	361	16	15	15	NUM
admet-34	361	17	(	(	PUNCT
admet-34	361	18	1983	1983	NUM
admet-34	361	19	)	)	PUNCT
admet-34	361	20	275	275	NUM
admet-34	361	21	–	–	PUNCT
admet-34	361	22	287	287	NUM
admet-34	361	23	.	.	PUNCT
admet-34	362	1	[	[	X
admet-34	362	2	19	19	NUM
admet-34	362	3	]	]	X
admet-34	362	4	n.	n.	NOUN
admet-34	362	5	coceani	coceani	PROPN
admet-34	362	6	,	,	PUNCT
admet-34	362	7	l.	l.	PROPN
admet-34	362	8	magarotto	magarotto	PROPN
admet-34	362	9	,	,	PUNCT
admet-34	362	10	d.	d.	PROPN
admet-34	362	11	ceschia	ceschia	PROPN
admet-34	362	12	,	,	PUNCT
admet-34	362	13	i.	i.	PROPN
admet-34	362	14	colombo	colombo	PROPN
admet-34	362	15	m.	m.	PROPN
admet-34	362	16	grassi	grassi	PROPN
admet-34	362	17	,	,	PUNCT
admet-34	362	18	chemical	chemical	NOUN
admet-34	362	19	engineering	engineering	NOUN
admet-34	362	20	science	science	NOUN
admet-34	362	21	71	71	NUM
admet-34	362	22	(	(	PUNCT
admet-34	362	23	2012	2012	NUM
admet-34	362	24	)	)	PUNCT
admet-34	362	25	345	345	NUM
admet-34	362	26	–	–	PUNCT
admet-34	362	27	355	355	NUM
admet-34	362	28	.	.	PUNCT
admet-34	363	1	[	[	X
admet-34	363	2	20	20	NUM
admet-34	363	3	]	]	PUNCT
admet-34	363	4	h.	h.	PROPN
admet-34	363	5	nogami	nogami	PROPN
admet-34	363	6	,	,	PUNCT
admet-34	363	7	t.	t.	PROPN
admet-34	363	8	nagai	nagai	PROPN
admet-34	363	9	,	,	PUNCT
admet-34	363	10	t.	t.	PROPN
admet-34	363	11	youtsuyanagi	youtsuyanagi	NOUN
admet-34	363	12	,	,	PUNCT
admet-34	363	13	chemical	chemical	NOUN
admet-34	363	14	and	and	CCONJ
admet-34	363	15	pharmaceutical	pharmaceutical	NOUN
admet-34	363	16	bulletin	bulletin	NOUN
admet-34	363	17	17	17	NUM
admet-34	363	18	(	(	PUNCT
admet-34	363	19	1969	1969	NUM
admet-34	363	20	)	)	PUNCT
admet-34	363	21	499	499	NUM
admet-34	363	22	–	–	PUNCT
admet-34	363	23	509	509	NUM
admet-34	363	24	.	.	PUNCT
admet-34	364	1	[	[	X
admet-34	364	2	21	21	NUM
admet-34	364	3	]	]	X
admet-34	364	4	s.c	s.c	PROPN
admet-34	364	5	.	.	PROPN
admet-34	364	6	chapra	chapra	PROPN
admet-34	364	7	,	,	PUNCT
admet-34	364	8	r.	r.	PROPN
admet-34	364	9	p.	p.	PROPN
admet-34	364	10	canale	canale	PROPN
admet-34	364	11	,	,	PUNCT
admet-34	364	12	numerical	numerical	ADJ
admet-34	364	13	methods	method	NOUN
admet-34	364	14	for	for	ADP
admet-34	364	15	engineers	engineer	NOUN
admet-34	364	16	,	,	PUNCT
admet-34	364	17	mcgraw	mcgraw	PROPN
admet-34	364	18	-	-	PUNCT
admet-34	364	19	hill	hill	PROPN
admet-34	364	20	,	,	PUNCT
admet-34	364	21	boston	boston	PROPN
admet-34	364	22	,	,	PUNCT
admet-34	364	23	usa	usa	PROPN
admet-34	364	24	,	,	PUNCT
admet-34	364	25	1998	1998	NUM
admet-34	364	26	third	third	PROPN
admet-34	364	27	edition	edition	NOUN
admet-34	364	28	.	.	PUNCT
admet-34	365	1	[	[	X
admet-34	365	2	22	22	NUM
admet-34	365	3	]	]	PUNCT
admet-34	365	4	s.	s.	PROPN
admet-34	365	5	v.	v.	PROPN
admet-34	365	6	patankar	patankar	PROPN
admet-34	365	7	,	,	PUNCT
admet-34	365	8	numerical	numerical	ADJ
admet-34	365	9	heat	heat	NOUN
admet-34	365	10	transfer	transfer	NOUN
admet-34	365	11	and	and	CCONJ
admet-34	365	12	fluid	fluid	NOUN
admet-34	365	13	flow	flow	NOUN
admet-34	365	14	,	,	PUNCT
admet-34	365	15	hemisphere	hemisphere	ADJ
admet-34	365	16	publishing	publishing	NOUN
admet-34	365	17	,	,	PUNCT
admet-34	365	18	new	new	PROPN
admet-34	365	19	york	york	PROPN
admet-34	365	20	,	,	PUNCT
admet-34	365	21	usa	usa	PROPN
admet-34	365	22	,	,	PUNCT
admet-34	365	23	1986	1986	NUM
admet-34	365	24	.	.	PUNCT
admet-34	366	1	[	[	X
admet-34	366	2	23	23	NUM
admet-34	366	3	]	]	X
admet-34	366	4	f.	f.	PROPN
admet-34	366	5	podczeck	podczeck	PROPN
admet-34	366	6	,	,	PUNCT
admet-34	366	7	international	international	ADJ
admet-34	366	8	journal	journal	NOUN
admet-34	366	9	of	of	ADP
admet-34	366	10	pharmaceutics	pharmaceutic	NOUN
admet-34	366	11	395	395	NUM
admet-34	366	12	(	(	PUNCT
admet-34	366	13	2010	2010	NUM
admet-34	366	14	)	)	PUNCT
admet-34	366	15	1	1	NUM
admet-34	366	16	–	–	PUNCT
admet-34	366	17	1	1	NUM
admet-34	366	18	.	.	PUNCT
admet-34	367	1	[	[	X
admet-34	367	2	24	24	NUM
admet-34	367	3	]	]	X
admet-34	367	4	j.	j.	PROPN
admet-34	367	5	m.	m.	PROPN
admet-34	367	6	newton	newton	PROPN
admet-34	367	7	,	,	PUNCT
admet-34	367	8	international	international	ADJ
admet-34	367	9	journal	journal	NOUN
admet-34	367	10	of	of	ADP
admet-34	367	11	pharmaceutics	pharmaceutic	NOUN
admet-34	367	12	395	395	NUM
admet-34	367	13	,	,	PUNCT
admet-34	367	14	(	(	PUNCT
admet-34	367	15	2010	2010	NUM
admet-34	367	16	)	)	PUNCT
admet-34	367	17	2	2	NUM
admet-34	367	18	–	–	PUNCT
admet-34	367	19	8	8	NUM
admet-34	367	20	.	.	PUNCT
admet-34	368	1	[	[	X
admet-34	368	2	25	25	NUM
admet-34	368	3	]	]	PUNCT
admet-34	368	4	k.	k.	PROPN
admet-34	368	5	h.	h.	PROPN
admet-34	368	6	yuen	yuen	PROPN
admet-34	368	7	,	,	PUNCT
admet-34	368	8	international	international	ADJ
admet-34	368	9	journal	journal	NOUN
admet-34	368	10	of	of	ADP
admet-34	368	11	pharmaceutics	pharmaceutic	NOUN
admet-34	368	12	395	395	NUM
admet-34	368	13	(	(	PUNCT
admet-34	368	14	2010	2010	NUM
admet-34	368	15	)	)	PUNCT
admet-34	368	16	9	9	NUM
admet-34	368	17	–	–	PUNCT
admet-34	368	18	16	16	NUM
admet-34	368	19	[	[	X
admet-34	368	20	26	26	NUM
admet-34	368	21	]	]	X
admet-34	368	22	c.	c.	PROPN
admet-34	368	23	g.	g.	PROPN
admet-34	368	24	wilson	wilson	PROPN
admet-34	368	25	,	,	PUNCT
admet-34	368	26	international	international	ADJ
admet-34	368	27	journal	journal	NOUN
admet-34	368	28	of	of	ADP
admet-34	368	29	pharmaceutics	pharmaceutic	NOUN
admet-34	368	30	395	395	NUM
admet-34	368	31	(	(	PUNCT
admet-34	368	32	2010	2010	NUM
admet-34	368	33	)	)	PUNCT
admet-34	368	34	17	17	NUM
admet-34	368	35	–	–	PUNCT
admet-34	368	36	25	25	NUM
admet-34	368	37	.	.	PUNCT
admet-34	369	1	[	[	X
admet-34	369	2	27	27	NUM
admet-34	369	3	]	]	X
admet-34	369	4	f.	f.	PROPN
admet-34	369	5	j.	j.	PROPN
admet-34	369	6	o.	o.	PROPN
admet-34	369	7	varum	varum	PROPN
admet-34	369	8	,	,	PUNCT
admet-34	369	9	h.	h.	PROPN
admet-34	369	10	a.	a.	NOUN
admet-34	369	11	merchant	merchant	PROPN
admet-34	369	12	,	,	PUNCT
admet-34	369	13	a.	a.	PROPN
admet-34	369	14	w.	w.	PROPN
admet-34	369	15	basit	basit	PROPN
admet-34	369	16	,	,	PUNCT
admet-34	369	17	international	international	ADJ
admet-34	369	18	journal	journal	NOUN
admet-34	369	19	of	of	ADP
admet-34	369	20	pharmaceutics	pharmaceutic	NOUN
admet-34	369	21	395	395	NUM
admet-34	369	22	(	(	PUNCT
admet-34	369	23	2010	2010	NUM
admet-34	369	24	)	)	PUNCT
admet-34	369	25	26	26	NUM
admet-34	369	26	–	–	SYM
admet-34	369	27	36	36	NUM
admet-34	369	28	.	.	X
admet-34	370	1	admet	admet	PROPN
admet-34	370	2	&	&	CCONJ
admet-34	370	3	dmpk	dmpk	PROPN
admet-34	370	4	2(2	2(2	NUM
admet-34	370	5	)	)	PUNCT
admet-34	370	6	(	(	PUNCT
admet-34	370	7	2014	2014	NUM
admet-34	370	8	)	)	PUNCT
admet-34	370	9	80	80	NUM
admet-34	370	10	-	-	SYM
admet-34	370	11	97	97	NUM
admet-34	370	12	in	in	ADP
admet-34	370	13	vivo	vivo	ADJ
admet-34	370	14	drug	drug	NOUN
admet-34	370	15	release	release	NOUN
admet-34	370	16	and	and	CCONJ
admet-34	370	17	absorption	absorption	NOUN
admet-34	370	18	doi	doi	NOUN
admet-34	370	19	:	:	PUNCT
admet-34	370	20	10.5599	10.5599	NUM
admet-34	370	21	/	/	SYM
admet-34	370	22	admet.2.2.34	admet.2.2.34	ADP
admet-34	370	23	95	95	NUM
admet-34	371	1	[	[	X
admet-34	371	2	28	28	NUM
admet-34	371	3	]	]	X
admet-34	371	4	a.	a.	NOUN
admet-34	371	5	bowles	bowles	PROPN
admet-34	371	6	,	,	PUNCT
admet-34	371	7	j.	j.	PROPN
admet-34	371	8	keane	keane	PROPN
admet-34	371	9	,	,	PUNCT
admet-34	371	10	t.	t.	PROPN
admet-34	371	11	ernest	ernest	PROPN
admet-34	371	12	,	,	PUNCT
admet-34	371	13	d.	d.	PROPN
admet-34	371	14	clapham	clapham	PROPN
admet-34	371	15	,	,	PUNCT
admet-34	371	16	c.	c.	PROPN
admet-34	371	17	tuleua	tuleua	PROPN
admet-34	371	18	,	,	PUNCT
admet-34	371	19	international	international	ADJ
admet-34	371	20	journal	journal	NOUN
admet-34	371	21	of	of	ADP
admet-34	371	22	pharmaceutics	pharmaceutic	NOUN
admet-34	371	23	395	395	NUM
admet-34	371	24	(	(	PUNCT
admet-34	371	25	2010	2010	NUM
admet-34	371	26	)	)	PUNCT
admet-34	371	27	37	37	NUM
admet-34	371	28	–	–	SYM
admet-34	371	29	43	43	NUM
admet-34	371	30	.	.	PUNCT
admet-34	372	1	[	[	X
admet-34	372	2	29	29	NUM
admet-34	372	3	]	]	PUNCT
admet-34	372	4	j.	j.	PROPN
admet-34	372	5	f.	f.	PROPN
admet-34	372	6	pinto	pinto	PROPN
admet-34	372	7	,	,	PUNCT
admet-34	372	8	international	international	ADJ
admet-34	372	9	journal	journal	NOUN
admet-34	372	10	of	of	ADP
admet-34	372	11	pharmaceutics	pharmaceutic	NOUN
admet-34	372	12	395	395	NUM
admet-34	372	13	(	(	PUNCT
admet-34	372	14	2010	2010	NUM
admet-34	372	15	)	)	PUNCT
admet-34	372	16	44	44	NUM
admet-34	372	17	–	–	PUNCT
admet-34	372	18	52	52	NUM
admet-34	372	19	[	[	SYM
admet-34	372	20	30	30	NUM
admet-34	372	21	]	]	PUNCT
admet-34	372	22	a.	a.	NOUN
admet-34	372	23	bernareggi	bernareggi	PROPN
admet-34	372	24	,	,	PUNCT
admet-34	372	25	clinical	clinical	ADJ
admet-34	372	26	pharmacokinetics	pharmacokinetic	NOUN
admet-34	372	27	35	35	NUM
admet-34	372	28	(	(	PUNCT
admet-34	372	29	1998	1998	NUM
admet-34	372	30	)	)	PUNCT
admet-34	372	31	247	247	NUM
admet-34	372	32	–	–	PUNCT
admet-34	372	33	274	274	NUM
admet-34	372	34	.	.	PUNCT
admet-34	373	1	[	[	X
admet-34	373	2	31	31	NUM
admet-34	373	3	]	]	PUNCT
admet-34	373	4	p.	p.	PROPN
admet-34	373	5	r.	r.	PROPN
admet-34	373	6	b.	b.	PROPN
admet-34	373	7	fallavena	fallavena	PROPN
admet-34	373	8	,	,	PUNCT
admet-34	373	9	e.	e.	PROPN
admet-34	373	10	e.	e.	PROPN
admet-34	373	11	s.	s.	PROPN
admet-34	373	12	schapoval	schapoval	PROPN
admet-34	373	13	,	,	PUNCT
admet-34	373	14	international	international	ADJ
admet-34	373	15	journal	journal	NOUN
admet-34	373	16	of	of	ADP
admet-34	373	17	pharmaceutics	pharmaceutic	NOUN
admet-34	373	18	158	158	NUM
admet-34	373	19	(	(	PUNCT
admet-34	373	20	1997	1997	NUM
admet-34	373	21	)	)	PUNCT
admet-34	373	22	109	109	NUM
admet-34	373	23	–	–	PUNCT
admet-34	373	24	112	112	NUM
admet-34	373	25	.	.	PUNCT
admet-34	374	1	[	[	X
admet-34	374	2	32	32	NUM
admet-34	374	3	]	]	PUNCT
admet-34	374	4	m.	m.	NOUN
admet-34	374	5	grassi	grassi	PROPN
admet-34	374	6	,	,	PUNCT
admet-34	374	7	n.	n.	PROPN
admet-34	374	8	coceani	coceani	PROPN
admet-34	374	9	,	,	PUNCT
admet-34	374	10	l.	l.	PROPN
admet-34	374	11	magarotto	magarotto	PROPN
admet-34	374	12	,	,	PUNCT
admet-34	374	13	international	international	ADJ
admet-34	374	14	journal	journal	NOUN
admet-34	374	15	of	of	ADP
admet-34	374	16	pharmaceutics	pharmaceutic	NOUN
admet-34	374	17	239	239	NUM
admet-34	374	18	(	(	PUNCT
admet-34	374	19	2002	2002	NUM
admet-34	374	20	)	)	PUNCT
admet-34	374	21	157	157	NUM
admet-34	374	22	–	–	SYM
admet-34	374	23	169	169	NUM
admet-34	374	24	.	.	PUNCT
admet-34	375	1	[	[	X
admet-34	375	2	33	33	NUM
admet-34	375	3	]	]	PUNCT
admet-34	375	4	r.	r.	PROPN
admet-34	375	5	del	del	PROPN
admet-34	375	6	cont	cont	PROPN
admet-34	375	7	,	,	PUNCT
admet-34	375	8	graduating	graduate	VERB
admet-34	375	9	thesis	thesis	NOUN
admet-34	375	10	,	,	PUNCT
admet-34	375	11	trieste	trieste	NOUN
admet-34	375	12	university	university	NOUN
admet-34	375	13	,	,	PUNCT
admet-34	375	14	dept	dept	NOUN
admet-34	375	15	.	.	PROPN
admet-34	375	16	of	of	ADP
admet-34	375	17	engineering	engineering	NOUN
admet-34	375	18	and	and	CCONJ
admet-34	375	19	architecture	architecture	NOUN
admet-34	375	20	(	(	PUNCT
admet-34	375	21	2012	2012	NUM
admet-34	375	22	)	)	PUNCT
admet-34	375	23	.	.	PUNCT
admet-34	376	1	[	[	X
admet-34	376	2	34	34	NUM
admet-34	376	3	]	]	PUNCT
admet-34	376	4	a.	a.	NOUN
admet-34	376	5	bernareggi	bernareggi	PROPN
admet-34	376	6	,	,	PUNCT
admet-34	376	7	k.	k.	PROPN
admet-34	376	8	d.	d.	PROPN
admet-34	376	9	rainsford	rainsford	PROPN
admet-34	376	10	,	,	PUNCT
admet-34	376	11	in	in	ADP
admet-34	376	12	:	:	PUNCT
admet-34	376	13	k.	k.	PROPN
admet-34	376	14	d.	d.	PROPN
admet-34	376	15	rainsford	rainsford	PROPN
admet-34	376	16	k.d	k.d	PROPN
admet-34	376	17	.	.	PROPN
admet-34	376	18	,	,	PUNCT
admet-34	376	19	ed	ed	NOUN
admet-34	376	20	:	:	PUNCT
admet-34	376	21	nimesulide	nimesulide	NOUN
admet-34	376	22	-	-	PUNCT
admet-34	376	23	actions	action	NOUN
admet-34	376	24	and	and	CCONJ
admet-34	376	25	use	use	NOUN
admet-34	376	26	.	.	PUNCT
admet-34	377	1	2005	2005	NUM
admet-34	377	2	,	,	PUNCT
admet-34	377	3	birkhäuser	birkhäuser	PROPN
admet-34	377	4	basel	basel	PROPN
admet-34	377	5	.	.	PUNCT
admet-34	378	1	[	[	X
admet-34	378	2	35	35	NUM
admet-34	378	3	]	]	X
admet-34	378	4	ppl	ppl	PROPN
admet-34	378	5	322	322	NUM
admet-34	378	6	1999	1999	NUM
admet-34	378	7	(	(	PUNCT
admet-34	378	8	pharmaceutical	pharmaceutical	NOUN
admet-34	378	9	profiles	profile	NOUN
admet-34	378	10	-	-	PUNCT
admet-34	378	11	ppl	ppl	ADJ
admet-34	378	12	322	322	NUM
admet-34	378	13	1999	1999	NUM
admet-34	378	14	,	,	PUNCT
admet-34	378	15	intelsite	intelsite	ADJ
admet-34	378	16	)	)	PUNCT
admet-34	378	17	.	.	PUNCT
admet-34	379	1	list	list	NOUN
admet-34	379	2	of	of	ADP
admet-34	379	3	symbols	symbol	NOUN
admet-34	379	4	adme	adme	NOUN
admet-34	379	5	adsorption	adsorption	NOUN
admet-34	379	6	,	,	PUNCT
admet-34	379	7	distribution	distribution	NOUN
admet-34	379	8	,	,	PUNCT
admet-34	379	9	metabolism	metabolism	NOUN
admet-34	379	10	,	,	PUNCT
admet-34	379	11	elimination	elimination	NOUN
admet-34	379	12	aj	aj	PROPN
admet-34	379	13	contact	contact	PROPN
admet-34	379	14	area	area	NOUN
admet-34	379	15	between	between	ADP
admet-34	379	16	the	the	DET
admet-34	379	17	release	release	NOUN
admet-34	379	18	environment	environment	NOUN
admet-34	379	19	and	and	CCONJ
admet-34	379	20	the	the	DET
admet-34	379	21	j	j	PROPN
admet-34	379	22	=	=	SYM
admet-34	379	23	gl	gl	PROPN
admet-34	379	24	,	,	PUNCT
admet-34	379	25	sil	sil	PROPN
admet-34	379	26	and	and	CCONJ
admet-34	379	27	lil	lil	PROPN
admet-34	379	28	gi	gi	NOUN
admet-34	379	29	tracts	tract	NOUN
admet-34	379	30	am	be	AUX
admet-34	379	31	dic	dic	ADJ
admet-34	379	32	concentration	concentration	NOUN
admet-34	379	33	of	of	ADP
admet-34	379	34	the	the	DET
admet-34	379	35	undissolved	undissolve	VERB
admet-34	379	36	amorphous	amorphous	ADJ
admet-34	379	37	drug	drug	PROPN
admet-34	379	38	nc	nc	PROPN
admet-34	379	39	dic	dic	PROPN
admet-34	379	40	concentration	concentration	NOUN
admet-34	379	41	of	of	ADP
admet-34	379	42	the	the	DET
admet-34	379	43	undissolved	undissolved	ADJ
admet-34	379	44	nano	nano	NOUN
admet-34	379	45	-	-	PUNCT
admet-34	379	46	crystalline	crystalline	NOUN
admet-34	379	47	drug	drug	NOUN
admet-34	379	48	mc	mc	PROPN
admet-34	379	49	dic	dic	PROPN
admet-34	379	50	concentration	concentration	NOUN
admet-34	379	51	of	of	ADP
admet-34	379	52	the	the	DET
admet-34	379	53	undissolved	undissolve	VERB
admet-34	379	54	micro	micro	ADJ
admet-34	379	55	-	-	ADJ
admet-34	379	56	crystalline	crystalline	ADJ
admet-34	379	57	drug	drug	NOUN
admet-34	379	58	cgics	cgic	NOUN
admet-34	379	59	drug	drug	NOUN
admet-34	379	60	concentration	concentration	NOUN
admet-34	379	61	in	in	ADP
admet-34	379	62	the	the	DET
admet-34	379	63	gastro	gastro	ADJ
admet-34	379	64	intestinal	intestinal	ADJ
admet-34	379	65	circulatory	circulatory	ADJ
admet-34	379	66	system	system	NOUN
admet-34	379	67	ci	ci	NOUN
admet-34	379	68	drug	drug	NOUN
admet-34	379	69	concentration	concentration	NOUN
admet-34	379	70	in	in	ADP
admet-34	379	71	the	the	DET
admet-34	379	72	i	i	NOUN
admet-34	379	73	th	th	X
admet-34	379	74	polymeric	polymeric	ADJ
admet-34	379	75	particle	particle	NOUN
admet-34	379	76	cl	cl	NOUN
admet-34	379	77	drug	drug	NOUN
admet-34	379	78	concentration	concentration	NOUN
admet-34	379	79	in	in	ADP
admet-34	379	80	the	the	DET
admet-34	379	81	liver	liver	NOUN
admet-34	379	82	clh	clh	PROPN
admet-34	379	83	hepatic	hepatic	PROPN
admet-34	379	84	clearance	clearance	NOUN
admet-34	379	85	cp	cp	PROPN
admet-34	379	86	drug	drug	NOUN
admet-34	379	87	concentration	concentration	NOUN
admet-34	379	88	in	in	ADP
admet-34	379	89	the	the	DET
admet-34	379	90	plasma	plasma	NOUN
admet-34	379	91	cpi	cpi	NOUN
admet-34	379	92	solvent	solvent	NOUN
admet-34	379	93	concentration	concentration	NOUN
admet-34	379	94	in	in	ADP
admet-34	379	95	the	the	DET
admet-34	379	96	polymeric	polymeric	ADJ
admet-34	379	97	particle	particle	NOUN
admet-34	379	98	of	of	ADP
admet-34	379	99	class	class	NOUN
admet-34	380	1	i	i	PRON
admet-34	380	2	th	th	AUX
admet-34	380	3	cpint	cpint	VERB
admet-34	380	4	solvent	solvent	NOUN
admet-34	380	5	concentration	concentration	NOUN
admet-34	380	6	at	at	ADP
admet-34	380	7	the	the	DET
admet-34	380	8	polymeric	polymeric	ADJ
admet-34	380	9	particle	particle	NOUN
admet-34	380	10	/	/	SYM
admet-34	380	11	solvent	solvent	NOUN
admet-34	380	12	interface	interface	NOUN
admet-34	380	13	cpeq	cpeq	NOUN
admet-34	380	14	equilibrium	equilibrium	NOUN
admet-34	380	15	solvent	solvent	NOUN
admet-34	380	16	concentration	concentration	NOUN
admet-34	380	17	in	in	ADP
admet-34	380	18	the	the	DET
admet-34	380	19	polymeric	polymeric	ADJ
admet-34	380	20	particles	particle	NOUN
admet-34	380	21	cr	cr	ADP
admet-34	380	22	drug	drug	NOUN
admet-34	380	23	concentration	concentration	NOUN
admet-34	380	24	in	in	ADP
admet-34	380	25	the	the	DET
admet-34	380	26	release	release	NOUN
admet-34	380	27	environment	environment	NOUN
admet-34	380	28	csgl	csgl	PROPN
admet-34	380	29	drug	drug	NOUN
admet-34	380	30	solubility	solubility	NOUN
admet-34	380	31	in	in	ADP
admet-34	380	32	the	the	DET
admet-34	380	33	gastric	gastric	ADJ
admet-34	380	34	lumen	luman	NOUN
admet-34	380	35	cssil	cssil	NOUN
admet-34	380	36	drug	drug	NOUN
admet-34	380	37	solubility	solubility	NOUN
admet-34	380	38	in	in	ADP
admet-34	380	39	the	the	DET
admet-34	380	40	small	small	ADJ
admet-34	380	41	intestine	intestine	NOUN
admet-34	380	42	lumen	luman	NOUN
admet-34	380	43	cslil	cslil	PROPN
admet-34	380	44	drug	drug	NOUN
admet-34	380	45	solubility	solubility	NOUN
admet-34	380	46	in	in	ADP
admet-34	380	47	the	the	DET
admet-34	380	48	large	large	ADJ
admet-34	380	49	intestine	intestine	NOUN
admet-34	380	50	lumen	luman	NOUN
admet-34	380	51	am	be	AUX
admet-34	380	52	sc	sc	PROPN
admet-34	380	53	time	time	NOUN
admet-34	380	54	dependent	dependent	ADJ
admet-34	380	55	amorphous	amorphous	ADJ
admet-34	380	56	drug	drug	NOUN
admet-34	380	57	solubility	solubility	NOUN
admet-34	380	58	in	in	ADP
admet-34	380	59	the	the	DET
admet-34	380	60	solvent	solvent	NOUN
admet-34	380	61	am	be	AUX
admet-34	380	62	s0c	s0c	PRON
admet-34	380	63	maximum	maximum	ADJ
admet-34	380	64	value	value	NOUN
admet-34	380	65	of	of	ADP
admet-34	380	66	the	the	DET
admet-34	380	67	amorphous	amorphous	ADJ
admet-34	380	68	drug	drug	NOUN
admet-34	380	69	solubility	solubility	NOUN
admet-34	380	70	in	in	ADP
admet-34	380	71	the	the	DET
admet-34	380	72	solvent	solvent	PROPN
admet-34	380	73	nc	nc	PROPN
admet-34	380	74	sc	sc	PROPN
admet-34	380	75	nano	nano	NOUN
admet-34	380	76	-	-	PUNCT
admet-34	380	77	crystalline	crystalline	NOUN
admet-34	380	78	drug	drug	NOUN
admet-34	380	79	solubility	solubility	NOUN
admet-34	380	80	in	in	ADP
admet-34	380	81	the	the	DET
admet-34	380	82	solvent	solvent	NOUN
admet-34	380	83	mc	mc	PROPN
admet-34	380	84	sc	sc	PROPN
admet-34	380	85	macro	macro	PROPN
admet-34	380	86	-	-	ADJ
admet-34	380	87	crystalline	crystalline	ADJ
admet-34	380	88	drug	drug	NOUN
admet-34	380	89	solubility	solubility	NOUN
admet-34	380	90	in	in	ADP
admet-34	380	91	the	the	DET
admet-34	380	92	solvent	solvent	ADJ
admet-34	380	93	ct	ct	PROPN
admet-34	380	94	drug	drug	NOUN
admet-34	380	95	concentration	concentration	NOUN
admet-34	380	96	in	in	ADP
admet-34	380	97	tissues	tissue	NOUN
admet-34	380	98	d	d	NOUN
admet-34	380	99	drug	drug	NOUN
admet-34	380	100	diffusion	diffusion	NOUN
admet-34	380	101	coefficient	coefficient	NOUN
admet-34	380	102	in	in	ADP
admet-34	380	103	the	the	DET
admet-34	380	104	swelling	swell	VERB
admet-34	380	105	polymeric	polymeric	ADJ
admet-34	380	106	network	network	NOUN
admet-34	380	107	d0	d0	PROPN
admet-34	380	108	fickian	fickian	ADJ
admet-34	380	109	solvent	solvent	NOUN
admet-34	380	110	diffusion	diffusion	NOUN
admet-34	380	111	coefficient	coefficient	NOUN
admet-34	380	112	dds	dds	PROPN
admet-34	380	113	drug	drug	NOUN
admet-34	380	114	diffusion	diffusion	NOUN
admet-34	380	115	coefficient	coefficient	NOUN
admet-34	380	116	in	in	ADP
admet-34	380	117	the	the	DET
admet-34	380	118	pure	pure	ADJ
admet-34	380	119	solvent	solvent	PROPN
admet-34	380	120	deq	deq	PROPN
admet-34	380	121	equilibrium	equilibrium	PROPN
admet-34	380	122	diffusion	diffusion	NOUN
admet-34	380	123	coefficient	coefficient	NOUN
admet-34	380	124	of	of	ADP
admet-34	380	125	solvent	solvent	PROPN
admet-34	380	126	dr	dr	PROPN
admet-34	380	127	non	non	ADJ
admet-34	380	128	-	-	ADJ
admet-34	380	129	fickian	fickian	ADJ
admet-34	380	130	solvent	solvent	NOUN
admet-34	380	131	diffusion	diffusion	NOUN
admet-34	380	132	coefficient	coefficient	NOUN
admet-34	380	133	f	f	PROPN
admet-34	380	134	ratio	ratio	NOUN
admet-34	380	135	between	between	ADP
admet-34	380	136	plasma	plasma	NOUN
admet-34	380	137	and	and	CCONJ
admet-34	380	138	tissues	tissue	NOUN
admet-34	380	139	volumes	volume	NOUN
admet-34	380	140	del	del	PROPN
admet-34	380	141	cont	cont	PROPN
admet-34	380	142	et	et	PROPN
admet-34	380	143	al	al	PROPN
admet-34	380	144	.	.	PROPN
admet-34	380	145	admet	admet	PROPN
admet-34	380	146	&	&	CCONJ
admet-34	380	147	dmpk	dmpk	PROPN
admet-34	380	148	2(2	2(2	NUM
admet-34	380	149	)	)	PUNCT
admet-34	380	150	(	(	PUNCT
admet-34	380	151	2014	2014	NUM
admet-34	380	152	)	)	PUNCT
admet-34	380	153	80	80	NUM
admet-34	380	154	-	-	SYM
admet-34	380	155	97	97	NUM
admet-34	380	156	96	96	NUM
admet-34	380	157	f	f	NOUN
admet-34	380	158	parameter	parameter	NOUN
admet-34	380	159	appearing	appear	VERB
admet-34	380	160	in	in	ADP
admet-34	380	161	eq.(12	eq.(12	NOUN
admet-34	380	162	)	)	PUNCT
admet-34	381	1	g	g	NOUN
admet-34	381	2	parameter	parameter	NOUN
admet-34	381	3	appearing	appear	VERB
admet-34	381	4	in	in	ADP
admet-34	381	5	eq.(12	eq.(12	NOUN
admet-34	381	6	)	)	PUNCT
admet-34	382	1	ha	ha	X
admet-34	382	2	epatic	epatic	ADJ
admet-34	382	3	artery	artery	NOUN
admet-34	382	4	hv	hv	PROPN
admet-34	383	1	epatic	epatic	ADJ
admet-34	383	2	vein	vein	NOUN
admet-34	383	3	gi	gi	NOUN
admet-34	383	4	gastro	gastro	ADJ
admet-34	383	5	-	-	PUNCT
admet-34	383	6	intestinal	intestinal	ADJ
admet-34	383	7	gics	gic	NOUN
admet-34	383	8	gastro	gastro	VERB
admet-34	383	9	intestinal	intestinal	ADJ
admet-34	383	10	circulatory	circulatory	ADJ
admet-34	383	11	system	system	NOUN
admet-34	383	12	gl	gl	NOUN
admet-34	383	13	gastric	gastric	ADJ
admet-34	383	14	lumen	luman	NOUN
admet-34	383	15	k	k	PROPN
admet-34	383	16	drug	drug	PROPN
admet-34	383	17	dissolution	dissolution	PROPN
admet-34	383	18	constant	constant	ADJ
admet-34	383	19	*	*	PUNCT
admet-34	383	20	elk	elk	NOUN
admet-34	383	21	drug	drug	NOUN
admet-34	383	22	elimination	elimination	NOUN
admet-34	383	23	constant	constant	ADJ
admet-34	383	24	in	in	ADP
admet-34	383	25	the	the	DET
admet-34	383	26	plasma	plasma	NOUN
admet-34	383	27	(	(	PUNCT
admet-34	383	28	volumetric	volumetric	NOUN
admet-34	383	29	flow	flow	NOUN
admet-34	383	30	)	)	PUNCT
admet-34	383	31	kel	kel	NOUN
admet-34	383	32	drug	drug	NOUN
admet-34	383	33	elimination	elimination	NOUN
admet-34	383	34	constant	constant	ADJ
admet-34	383	35	in	in	ADP
admet-34	383	36	the	the	DET
admet-34	383	37	plasma	plasma	NOUN
admet-34	383	38	(	(	PUNCT
admet-34	383	39	time-1	time-1	NOUN
admet-34	383	40	)	)	PUNCT
admet-34	383	41	*	*	PUNCT
admet-34	383	42	ptk	ptk	PROPN
admet-34	383	43	mass	mass	NOUN
admet-34	383	44	transfer	transfer	NOUN
admet-34	383	45	coefficient	coefficient	NOUN
admet-34	383	46	between	between	ADP
admet-34	383	47	plasma	plasma	NOUN
admet-34	383	48	and	and	CCONJ
admet-34	383	49	tissues	tissue	NOUN
admet-34	383	50	(	(	PUNCT
admet-34	383	51	volumetric	volumetric	NOUN
admet-34	383	52	flow	flow	NOUN
admet-34	383	53	)	)	PUNCT
admet-34	383	54	kpt	kpt	PROPN
admet-34	383	55	mass	mass	NOUN
admet-34	383	56	transfer	transfer	NOUN
admet-34	383	57	coefficient	coefficient	NOUN
admet-34	383	58	between	between	ADP
admet-34	383	59	plasma	plasma	NOUN
admet-34	383	60	and	and	CCONJ
admet-34	383	61	tissues	tissue	NOUN
admet-34	383	62	(	(	PUNCT
admet-34	383	63	time	time	NOUN
admet-34	383	64	-1	-1	PUNCT
admet-34	383	65	)	)	PUNCT
admet-34	384	1	*	*	PUNCT
admet-34	384	2	tpk	tpk	PROPN
admet-34	384	3	mass	mass	NOUN
admet-34	384	4	transfer	transfer	NOUN
admet-34	384	5	coefficient	coefficient	NOUN
admet-34	384	6	between	between	ADP
admet-34	384	7	tissues	tissue	NOUN
admet-34	384	8	and	and	CCONJ
admet-34	384	9	plasma	plasma	NOUN
admet-34	384	10	(	(	PUNCT
admet-34	384	11	volumetric	volumetric	NOUN
admet-34	384	12	flow	flow	NOUN
admet-34	384	13	)	)	PUNCT
admet-34	384	14	ktp	ktp	NOUN
admet-34	384	15	mass	mass	NOUN
admet-34	384	16	transfer	transfer	NOUN
admet-34	384	17	coefficient	coefficient	NOUN
admet-34	384	18	between	between	ADP
admet-34	384	19	tissues	tissue	NOUN
admet-34	384	20	and	and	CCONJ
admet-34	384	21	plasma	plasma	NOUN
admet-34	384	22	(	(	PUNCT
admet-34	384	23	time	time	NOUN
admet-34	384	24	-1	-1	PUNCT
admet-34	384	25	)	)	PUNCT
admet-34	384	26	re	re	ADP
admet-34	384	27	elk	elk	PROPN
admet-34	384	28	drug	drug	NOUN
admet-34	384	29	elimination	elimination	NOUN
admet-34	384	30	constant	constant	ADJ
admet-34	384	31	in	in	ADP
admet-34	384	32	the	the	DET
admet-34	384	33	gi	gi	PROPN
admet-34	384	34	tract	tract	NOUN
admet-34	384	35	kp	kp	PROPN
admet-34	384	36	partition	partition	PROPN
admet-34	384	37	coefficient	coefficient	NOUN
admet-34	384	38	(	(	PUNCT
admet-34	384	39	particle	particle	NOUN
admet-34	384	40	/	/	SYM
admet-34	384	41	solvent	solvent	NOUN
admet-34	384	42	)	)	PUNCT
admet-34	385	1	kr	kr	PROPN
admet-34	385	2	drug	drug	PROPN
admet-34	385	3	re	re	NOUN
admet-34	385	4	-	-	NOUN
admet-34	385	5	crystallisation	crystallisation	NOUN
admet-34	385	6	constant	constant	ADJ
admet-34	385	7	in	in	ADP
admet-34	385	8	the	the	DET
admet-34	385	9	polymeric	polymeric	ADJ
admet-34	385	10	network	network	NOUN
admet-34	385	11	krb	krb	X
admet-34	385	12	drug	drug	PROPN
admet-34	385	13	re	re	NOUN
admet-34	385	14	-	-	NOUN
admet-34	385	15	crystallisation	crystallisation	NOUN
admet-34	385	16	constant	constant	ADJ
admet-34	385	17	in	in	ADP
admet-34	385	18	the	the	DET
admet-34	385	19	release	release	NOUN
admet-34	385	20	environment	environment	NOUN
admet-34	385	21	ji	ji	PROPN
admet-34	385	22	solvent	solvent	PROPN
admet-34	385	23	flux	flux	NOUN
admet-34	385	24	(	(	PUNCT
admet-34	385	25	i	i	PRON
admet-34	385	26	th	th	VERB
admet-34	385	27	polymeric	polymeric	ADJ
admet-34	385	28	particle	particle	NOUN
admet-34	385	29	class	class	NOUN
admet-34	385	30	)	)	PUNCT
admet-34	385	31	jfi	jfi	PROPN
admet-34	385	32	fickian	fickian	ADJ
admet-34	385	33	component	component	NOUN
admet-34	385	34	of	of	ADP
admet-34	385	35	ji	ji	PROPN
admet-34	385	36	jri	jri	PROPN
admet-34	385	37	non	non	ADJ
admet-34	385	38	-	-	ADJ
admet-34	385	39	fickian	fickian	ADJ
admet-34	385	40	component	component	NOUN
admet-34	385	41	of	of	ADP
admet-34	385	42	ji	ji	PROPN
admet-34	385	43	lj	lj	PROPN
admet-34	385	44	release	release	VERB
admet-34	385	45	environment	environment	NOUN
admet-34	385	46	length	length	NOUN
admet-34	385	47	in	in	ADP
admet-34	385	48	j	j	PROPN
admet-34	385	49	=	=	SYM
admet-34	385	50	gl	gl	PROPN
admet-34	385	51	,	,	PUNCT
admet-34	385	52	sil	sil	PROPN
admet-34	385	53	,	,	PUNCT
admet-34	385	54	lil	lil	NOUN
admet-34	385	55	lil	lil	VERB
admet-34	386	1	large	large	ADJ
admet-34	386	2	intestine	intestine	NOUN
admet-34	386	3	lumen	luman	NOUN
admet-34	386	4	mc	mc	PROPN
admet-34	386	5	amount	amount	NOUN
admet-34	386	6	of	of	ADP
admet-34	386	7	the	the	DET
admet-34	386	8	drug	drug	NOUN
admet-34	386	9	re	re	VERB
admet-34	386	10	-	-	VERB
admet-34	386	11	crystallised	crystallised	ADJ
admet-34	386	12	in	in	ADP
admet-34	386	13	the	the	DET
admet-34	386	14	release	release	NOUN
admet-34	386	15	environment	environment	NOUN
admet-34	386	16	mel	mel	PROPN
admet-34	386	17	amount	amount	NOUN
admet-34	386	18	of	of	ADP
admet-34	386	19	drug	drug	NOUN
admet-34	386	20	eliminated	eliminate	VERB
admet-34	386	21	in	in	ADP
admet-34	386	22	the	the	DET
admet-34	386	23	gi	gi	NOUN
admet-34	386	24	tract	tract	NOUN
admet-34	386	25	,	,	PUNCT
admet-34	386	26	in	in	ADP
admet-34	386	27	the	the	DET
admet-34	386	28	plasma	plasma	NOUN
admet-34	386	29	and	and	CCONJ
admet-34	386	30	in	in	ADP
admet-34	386	31	the	the	DET
admet-34	386	32	liver	liver	NOUN
admet-34	386	33	m0	m0	PROPN
admet-34	386	34	drug	drug	PROPN
admet-34	386	35	dose	dose	PROPN
admet-34	386	36	nc	nc	PROPN
admet-34	386	37	number	number	NOUN
admet-34	386	38	of	of	ADP
admet-34	386	39	classes	class	NOUN
admet-34	386	40	characterised	characterise	VERB
admet-34	386	41	by	by	ADP
admet-34	386	42	polymeric	polymeric	ADJ
admet-34	386	43	particles	particle	NOUN
admet-34	386	44	having	have	VERB
admet-34	386	45	the	the	DET
admet-34	386	46	same	same	ADJ
admet-34	386	47	radius	radius	NOUN
admet-34	386	48	npi	npi	PROPN
admet-34	386	49	number	number	NOUN
admet-34	386	50	of	of	ADP
admet-34	386	51	particles	particle	NOUN
admet-34	386	52	belonging	belong	VERB
admet-34	386	53	to	to	ADP
admet-34	386	54	ith	ith	PROPN
admet-34	386	55	class	class	NOUN
admet-34	386	56	pbpk	pbpk	NOUN
admet-34	386	57	physiologically	physiologically	ADV
admet-34	386	58	based	base	VERB
admet-34	386	59	pharmacokinetic	pharmacokinetic	ADJ
admet-34	386	60	pk	pk	NOUN
admet-34	386	61	pharmacokinetic	pharmacokinetic	ADJ
admet-34	386	62	pgl	pgl	NOUN
admet-34	386	63	drug	drug	NOUN
admet-34	386	64	permeability	permeability	NOUN
admet-34	386	65	in	in	ADP
admet-34	386	66	the	the	DET
admet-34	386	67	gastric	gastric	ADJ
admet-34	386	68	lumen	luman	NOUN
admet-34	386	69	plil	plil	NOUN
admet-34	386	70	drug	drug	NOUN
admet-34	386	71	permeability	permeability	NOUN
admet-34	386	72	in	in	ADP
admet-34	386	73	the	the	DET
admet-34	386	74	large	large	ADJ
admet-34	386	75	intestine	intestine	NOUN
admet-34	386	76	lumen	luman	NOUN
admet-34	386	77	pos	pos	NOUN
admet-34	386	78	release	release	NOUN
admet-34	386	79	environment	environment	NOUN
admet-34	386	80	position	position	NOUN
admet-34	386	81	in	in	ADP
admet-34	386	82	the	the	DET
admet-34	386	83	gi	gi	NOUN
admet-34	386	84	tract	tract	NOUN
admet-34	386	85	psil	psil	NOUN
admet-34	386	86	drug	drug	NOUN
admet-34	386	87	permeability	permeability	NOUN
admet-34	386	88	in	in	ADP
admet-34	386	89	the	the	DET
admet-34	386	90	small	small	ADJ
admet-34	386	91	intestine	intestine	NOUN
admet-34	386	92	lumen	luman	NOUN
admet-34	386	93	pv	pv	INTJ
admet-34	387	1	portal	portal	PROPN
admet-34	387	2	vein	vein	VERB
admet-34	387	3	qhv	qhv	NOUN
admet-34	387	4	blood	blood	NOUN
admet-34	387	5	volumetric	volumetric	NOUN
admet-34	387	6	flow	flow	NOUN
admet-34	387	7	of	of	ADP
admet-34	387	8	the	the	DET
admet-34	387	9	hepatic	hepatic	ADJ
admet-34	387	10	vein	vein	PROPN
admet-34	387	11	qha	qha	PROPN
admet-34	387	12	blood	blood	NOUN
admet-34	387	13	volumetric	volumetric	NOUN
admet-34	387	14	flow	flow	NOUN
admet-34	387	15	of	of	ADP
admet-34	387	16	the	the	DET
admet-34	387	17	hepatic	hepatic	ADJ
admet-34	387	18	artery	artery	NOUN
admet-34	387	19	qpv	qpv	NOUN
admet-34	387	20	blood	blood	NOUN
admet-34	387	21	volumetric	volumetric	NOUN
admet-34	387	22	flow	flow	NOUN
admet-34	387	23	of	of	ADP
admet-34	387	24	the	the	DET
admet-34	387	25	portal	portal	ADJ
admet-34	387	26	vein	vein	VERB
admet-34	388	1	ri	ri	PROPN
admet-34	389	1	j	j	PROPN
admet-34	389	2	internal	internal	ADJ
admet-34	389	3	radius	radius	NOUN
admet-34	389	4	of	of	ADP
admet-34	389	5	the	the	DET
admet-34	389	6	release	release	NOUN
admet-34	389	7	environment	environment	NOUN
admet-34	389	8	in	in	ADP
admet-34	389	9	the	the	DET
admet-34	389	10	j	j	PROPN
admet-34	389	11	=	=	SYM
admet-34	389	12	gl	gl	PROPN
admet-34	389	13	,	,	PUNCT
admet-34	389	14	sil	sil	PROPN
admet-34	389	15	and	and	CCONJ
admet-34	389	16	lil	lil	NOUN
admet-34	389	17	ri	ri	NOUN
admet-34	389	18	radial	radial	ADJ
admet-34	389	19	coordinate	coordinate	NOUN
admet-34	389	20	(	(	PUNCT
admet-34	389	21	ith	ith	PROPN
admet-34	389	22	particle	particle	NOUN
admet-34	389	23	class	class	NOUN
admet-34	389	24	)	)	PUNCT
admet-34	390	1	i	i	PRON
admet-34	390	2	glr	glr	PROPN
admet-34	390	3	internal	internal	ADJ
admet-34	390	4	radius	radius	NOUN
admet-34	390	5	of	of	ADP
admet-34	390	6	the	the	DET
admet-34	390	7	gastric	gastric	ADJ
admet-34	390	8	lumen	luman	NOUN
admet-34	390	9	admet	admet	PROPN
admet-34	390	10	&	&	CCONJ
admet-34	390	11	dmpk	dmpk	PROPN
admet-34	390	12	2(2	2(2	NUM
admet-34	390	13	)	)	PUNCT
admet-34	390	14	(	(	PUNCT
admet-34	390	15	2014	2014	NUM
admet-34	390	16	)	)	PUNCT
admet-34	390	17	80	80	NUM
admet-34	390	18	-	-	SYM
admet-34	390	19	97	97	NUM
admet-34	390	20	in	in	ADP
admet-34	390	21	vivo	vivo	ADJ
admet-34	390	22	drug	drug	NOUN
admet-34	390	23	release	release	NOUN
admet-34	390	24	and	and	CCONJ
admet-34	390	25	absorption	absorption	NOUN
admet-34	390	26	doi	doi	NOUN
admet-34	390	27	:	:	PUNCT
admet-34	390	28	10.5599	10.5599	NUM
admet-34	390	29	/	/	SYM
admet-34	390	30	admet.2.2.34	admet.2.2.34	PRON
admet-34	390	31	97	97	NUM
admet-34	391	1	i	i	PRON
admet-34	391	2	lilr	lilr	VERB
admet-34	391	3	internal	internal	ADJ
admet-34	391	4	radius	radius	NOUN
admet-34	391	5	of	of	ADP
admet-34	391	6	the	the	DET
admet-34	391	7	large	large	ADJ
admet-34	391	8	intestine	intestine	NOUN
admet-34	391	9	lumen	luman	NOUN
admet-34	391	10	i	i	PRON
admet-34	391	11	silr	silr	VERB
admet-34	391	12	internal	internal	ADJ
admet-34	391	13	radius	radius	NOUN
admet-34	391	14	of	of	ADP
admet-34	391	15	the	the	DET
admet-34	391	16	small	small	ADJ
admet-34	391	17	intestine	intestine	NOUN
admet-34	391	18	lumen	luman	NOUN
admet-34	391	19	rp	rp	ADP
admet-34	391	20	polymeric	polymeric	ADJ
admet-34	391	21	particle	particle	NOUN
admet-34	391	22	radius	radius	NOUN
admet-34	391	23	rpi	rpi	NOUN
admet-34	391	24	radius	radius	NOUN
admet-34	391	25	of	of	ADP
admet-34	391	26	the	the	DET
admet-34	391	27	i	i	NOUN
admet-34	391	28	th	th	X
admet-34	391	29	polymeric	polymeric	ADJ
admet-34	391	30	particle	particle	NOUN
admet-34	391	31	class	class	NOUN
admet-34	391	32	rmax	rmax	ADJ
admet-34	391	33	maximum	maximum	ADJ
admet-34	391	34	value	value	NOUN
admet-34	391	35	of	of	ADP
admet-34	391	36	rp	rp	NOUN
admet-34	391	37	rmin	rmin	ADJ
admet-34	391	38	minimum	minimum	NOUN
admet-34	391	39	value	value	NOUN
admet-34	391	40	of	of	ADP
admet-34	391	41	rp	rp	NOUN
admet-34	391	42	t	t	PROPN
admet-34	391	43	time	time	NOUN
admet-34	391	44	tem	tem	PROPN
admet-34	391	45	temazepam	temazepam	VERB
admet-34	391	46	tgl	tgl	PROPN
admet-34	391	47	gastric	gastric	ADJ
admet-34	391	48	lumen	luman	NOUN
admet-34	391	49	transit	transit	PROPN
admet-34	391	50	time	time	NOUN
admet-34	391	51	tlil	tlil	VERB
admet-34	391	52	large	large	ADJ
admet-34	391	53	intestine	intestine	NOUN
admet-34	391	54	lumen	luman	NOUN
admet-34	391	55	transit	transit	PROPN
admet-34	391	56	time	time	NOUN
admet-34	391	57	tsil	tsil	NOUN
admet-34	391	58	small	small	ADJ
admet-34	391	59	intestine	intestine	NOUN
admet-34	391	60	lumen	luman	NOUN
admet-34	391	61	transit	transit	PROPN
admet-34	391	62	time	time	NOUN
admet-34	391	63	tt	tt	PROPN
admet-34	391	64	gi	gi	INTJ
admet-34	391	65	tract	tract	NOUN
admet-34	391	66	transit	transit	NOUN
admet-34	391	67	time	time	NOUN
admet-34	391	68	sil	sil	PROPN
admet-34	391	69	small	small	ADJ
admet-34	391	70	intestine	intestine	NOUN
admet-34	391	71	lumen	luman	NOUN
admet-34	391	72	v	v	ADP
admet-34	391	73	volume	volume	NOUN
admet-34	391	74	of	of	ADP
admet-34	391	75	the	the	DET
admet-34	391	76	polymeric	polymeric	ADJ
admet-34	391	77	particles	particle	NOUN
admet-34	391	78	with	with	ADP
admet-34	391	79	radius	radius	NOUN
admet-34	391	80	lower	low	ADJ
admet-34	391	81	than	than	ADP
admet-34	391	82	or	or	CCONJ
admet-34	391	83	equal	equal	ADJ
admet-34	391	84	to	to	ADP
admet-34	391	85	rp	rp	NOUN
admet-34	391	86	v0	v0	NOUN
admet-34	391	87	volume	volume	NOUN
admet-34	391	88	of	of	ADP
admet-34	391	89	all	all	DET
admet-34	391	90	the	the	DET
admet-34	391	91	polymeric	polymeric	ADJ
admet-34	391	92	particles	particle	NOUN
admet-34	391	93	vgics	vgic	NOUN
admet-34	391	94	volume	volume	NOUN
admet-34	391	95	of	of	ADP
admet-34	391	96	the	the	DET
admet-34	391	97	gastro	gastro	ADJ
admet-34	391	98	intestinal	intestinal	ADJ
admet-34	391	99	circulatory	circulatory	ADJ
admet-34	391	100	system	system	NOUN
admet-34	391	101	vl	vl	NOUN
admet-34	391	102	liver	liver	NOUN
admet-34	391	103	volume	volume	NOUN
admet-34	391	104	vp	vp	PROPN
admet-34	391	105	plasma	plasma	NOUN
admet-34	391	106	volume	volume	NOUN
admet-34	391	107	vre	vre	NOUN
admet-34	391	108	release	release	NOUN
admet-34	391	109	environment	environment	NOUN
admet-34	391	110	speed	speed	NOUN
admet-34	391	111	vr	vr	PROPN
admet-34	391	112	release	release	NOUN
admet-34	391	113	environment	environment	NOUN
admet-34	391	114	volume	volume	NOUN
admet-34	391	115	vt	vt	PROPN
admet-34	391	116	tissues	tissues	PROPN
admet-34	391	117	volume	volume	NOUN
admet-34	391	118	greek	greek	NOUN
admet-34	391	119	letters	letter	NOUN
admet-34	391	120	s	s	VERB
admet-34	391	121	solvent	solvent	NOUN
admet-34	391	122	density	density	NOUN
admet-34	391	123			NUM
admet-34	391	124	weibull	weibull	PROPN
admet-34	391	125	model	model	NOUN
admet-34	391	126	parameter	parameter	PROPN
admet-34	391	127	(	(	PUNCT
admet-34	391	128	eq.(9	eq.(9	ADJ
admet-34	391	129	)	)	PUNCT
admet-34	391	130	)	)	PUNCT
admet-34	392	1			NUM
admet-34	392	2	weibull	weibull	PROPN
admet-34	392	3	model	model	NOUN
admet-34	392	4	parameter	parameter	NOUN
admet-34	392	5	(	(	PUNCT
admet-34	392	6	eq.(9	eq.(9	ADJ
admet-34	392	7	)	)	PUNCT
admet-34	392	8	)	)	PUNCT
admet-34	392	9			NOUN
admet-34	392	10	relaxation	relaxation	NOUN
admet-34	392	11	time	time	NOUN
admet-34	392	12	of	of	ADP
admet-34	392	13	the	the	DET
admet-34	392	14	polymer	polymer	NOUN
admet-34	392	15	-	-	PUNCT
admet-34	392	16	solvent	solvent	NOUN
admet-34	392	17	system	system	NOUN
admet-34	392	18	(	(	PUNCT
admet-34	392	19	eq.(11	eq.(11	NOUN
admet-34	392	20	)	)	PUNCT
admet-34	392	21	)	)	PUNCT
admet-34	392	22	eq	eq	NOUN
admet-34	392	23	relaxation	relaxation	NOUN
admet-34	392	24	time	time	NOUN
admet-34	392	25	of	of	ADP
admet-34	392	26	the	the	DET
admet-34	392	27	polymer	polymer	NOUN
admet-34	392	28	-	-	PUNCT
admet-34	392	29	solvent	solvent	NOUN
admet-34	392	30	system	system	NOUN
admet-34	392	31	(	(	PUNCT
admet-34	392	32	eq.(12	eq.(12	PROPN
admet-34	392	33	)	)	PUNCT
admet-34	392	34	)	)	PUNCT
admet-34	393	1	©	©	PROPN
admet-34	393	2	2014	2014	NUM
admet-34	393	3	by	by	ADP
admet-34	393	4	the	the	DET
admet-34	393	5	authors	author	NOUN
admet-34	393	6	;	;	PUNCT
admet-34	393	7	licensee	licensee	PROPN
admet-34	393	8	iapc	iapc	PROPN
admet-34	393	9	,	,	PUNCT
admet-34	393	10	zagreb	zagreb	PROPN
admet-34	393	11	,	,	PUNCT
admet-34	393	12	croatia	croatia	PROPN
admet-34	393	13	.	.	PUNCT
admet-34	394	1	this	this	DET
admet-34	394	2	article	article	NOUN
admet-34	394	3	is	be	AUX
admet-34	394	4	an	an	DET
admet-34	394	5	open	open	ADJ
admet-34	394	6	-	-	PUNCT
admet-34	394	7	access	access	NOUN
admet-34	394	8	article	article	NOUN
admet-34	394	9	distributed	distribute	VERB
admet-34	394	10	under	under	ADP
admet-34	394	11	the	the	DET
admet-34	394	12	terms	term	NOUN
admet-34	394	13	and	and	CCONJ
admet-34	394	14	conditions	condition	NOUN
admet-34	394	15	of	of	ADP
admet-34	394	16	the	the	DET
admet-34	394	17	creative	creative	ADJ
admet-34	394	18	commons	common	NOUN
admet-34	394	19	attribution	attribution	NOUN
admet-34	394	20	license	license	NOUN
admet-34	394	21	(	(	PUNCT
admet-34	394	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-34	394	23	)	)	PUNCT
admet-34	394	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN