id	sid	tid	token	lemma	pos
admet-346	1	1	doi	doi	NOUN
admet-346	1	2	:	:	PUNCT
admet-346	1	3	10.5599	10.5599	NUM
admet-346	1	4	/	/	SYM
admet-346	1	5	admet.5.1.346	admet.5.1.346	NUM
admet-346	1	6	39	39	NUM
admet-346	1	7	admet	admet	NOUN
admet-346	1	8	&	&	CCONJ
admet-346	1	9	dmpk	dmpk	PROPN
admet-346	1	10	5(1	5(1	NUM
admet-346	1	11	)	)	PUNCT
admet-346	1	12	(	(	PUNCT
admet-346	1	13	2017	2017	NUM
admet-346	1	14	)	)	PUNCT
admet-346	1	15	39	39	NUM
admet-346	1	16	-	-	SYM
admet-346	1	17	46	46	NUM
admet-346	1	18	;	;	PUNCT
admet-346	1	19	doi	doi	NOUN
admet-346	1	20	:	:	PUNCT
admet-346	1	21	10.5599	10.5599	NUM
admet-346	1	22	/	/	SYM
admet-346	1	23	admet.5.1.346	admet.5.1.346	PUNCT
admet-346	1	24	open	open	ADJ
admet-346	1	25	access	access	NOUN
admet-346	1	26	:	:	PUNCT
admet-346	1	27	issn	issn	PROPN
admet-346	1	28	:	:	PUNCT
admet-346	1	29	1848	1848	NUM
admet-346	1	30	-	-	SYM
admet-346	1	31	7718	7718	NUM
admet-346	1	32	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-346	1	33	original	original	ADJ
admet-346	1	34	scientific	scientific	ADJ
admet-346	1	35	paper	paper	NOUN
admet-346	1	36	biorelevant	biorelevant	NOUN
admet-346	1	37	dissolution	dissolution	NOUN
admet-346	1	38	of	of	ADP
admet-346	1	39	candesartan	candesartan	PROPN
admet-346	1	40	cilexetil	cilexetil	PROPN
admet-346	1	41	lucie	lucie	PROPN
admet-346	1	42	gruberová	gruberová	PROPN
admet-346	1	43	*	*	PUNCT
admet-346	1	44	and	and	CCONJ
admet-346	1	45	bohumil	bohumil	VERB
admet-346	1	46	kratochvíl	kratochvíl	PROPN
admet-346	1	47	department	department	PROPN
admet-346	1	48	of	of	ADP
admet-346	1	49	solid	solid	ADJ
admet-346	1	50	state	state	NOUN
admet-346	1	51	chemistry	chemistry	NOUN
admet-346	1	52	,	,	PUNCT
admet-346	1	53	university	university	NOUN
admet-346	1	54	of	of	ADP
admet-346	1	55	chemistry	chemistry	NOUN
admet-346	1	56	and	and	CCONJ
admet-346	1	57	technology	technology	NOUN
admet-346	1	58	prague	prague	NOUN
admet-346	1	59	,	,	PUNCT
admet-346	1	60	technická	technická	NOUN
admet-346	1	61	5	5	NUM
admet-346	1	62	,	,	PUNCT
admet-346	1	63	166	166	NUM
admet-346	1	64	28	28	NUM
admet-346	1	65	praha	praha	NOUN
admet-346	1	66	*	*	PUNCT
admet-346	1	67	corresponding	correspond	VERB
admet-346	1	68	author	author	NOUN
admet-346	1	69	:	:	PUNCT
admet-346	1	70	e	e	NOUN
admet-346	1	71	-	-	NOUN
admet-346	1	72	mail	mail	NOUN
admet-346	1	73	:	:	PUNCT
admet-346	1	74	gruberol@vscht.cz	gruberol@vscht.cz	ADJ
admet-346	1	75	;	;	PUNCT
admet-346	1	76	tel	tel	PROPN
admet-346	1	77	.	.	PUNCT
admet-346	1	78	:	:	PUNCT
admet-346	2	1	+420	+420	NUM
admet-346	2	2	220	220	NUM
admet-346	2	3	443	443	NUM
admet-346	2	4	692	692	NUM
admet-346	2	5	received	receive	VERB
admet-346	2	6	:	:	PUNCT
admet-346	2	7	september	september	PROPN
admet-346	2	8	26	26	NUM
admet-346	2	9	,	,	PUNCT
admet-346	2	10	2016	2016	NUM
admet-346	2	11	;	;	PUNCT
admet-346	2	12	revised	revise	VERB
admet-346	2	13	:	:	PUNCT
admet-346	2	14	december	december	PROPN
admet-346	2	15	16	16	NUM
admet-346	2	16	,	,	PUNCT
admet-346	2	17	2016	2016	NUM
admet-346	2	18	;	;	PUNCT
admet-346	2	19	published	publish	VERB
admet-346	2	20	:	:	PUNCT
admet-346	2	21	march	march	PROPN
admet-346	2	22	25	25	NUM
admet-346	2	23	,	,	PUNCT
admet-346	2	24	2017	2017	NUM
admet-346	2	25	abstract	abstract	NOUN
admet-346	2	26	the	the	DET
admet-346	2	27	choice	choice	NOUN
admet-346	2	28	of	of	ADP
admet-346	2	29	an	an	DET
admet-346	2	30	appropriate	appropriate	ADJ
admet-346	2	31	medium	medium	NOUN
admet-346	2	32	for	for	ADP
admet-346	2	33	dissolution	dissolution	NOUN
admet-346	2	34	tests	test	NOUN
admet-346	2	35	is	be	AUX
admet-346	2	36	an	an	DET
admet-346	2	37	essential	essential	ADJ
admet-346	2	38	step	step	NOUN
admet-346	2	39	during	during	ADP
admet-346	2	40	a	a	DET
admet-346	2	41	dosage	dosage	NOUN
admet-346	2	42	form	form	NOUN
admet-346	2	43	development	development	NOUN
admet-346	2	44	.	.	PUNCT
admet-346	3	1	the	the	DET
admet-346	3	2	adequate	adequate	ADJ
admet-346	3	3	design	design	NOUN
admet-346	3	4	of	of	ADP
admet-346	3	5	dissolution	dissolution	NOUN
admet-346	3	6	testing	testing	NOUN
admet-346	3	7	enables	enable	VERB
admet-346	3	8	forecasting	forecast	VERB
admet-346	3	9	in	in	ADP
admet-346	3	10	vivo	vivo	ADJ
admet-346	3	11	behavior	behavior	NOUN
admet-346	3	12	of	of	ADP
admet-346	3	13	drug	drug	NOUN
admet-346	3	14	formulation	formulation	NOUN
admet-346	3	15	.	.	PUNCT
admet-346	4	1	biorelevant	biorelevant	ADJ
admet-346	4	2	media	medium	NOUN
admet-346	4	3	were	be	AUX
admet-346	4	4	developed	develop	VERB
admet-346	4	5	for	for	ADP
admet-346	4	6	this	this	DET
admet-346	4	7	purpose	purpose	NOUN
admet-346	4	8	because	because	SCONJ
admet-346	4	9	dissolution	dissolution	ADJ
admet-346	4	10	media	medium	NOUN
admet-346	4	11	described	describe	VERB
admet-346	4	12	in	in	ADP
admet-346	4	13	the	the	DET
admet-346	4	14	international	international	ADJ
admet-346	4	15	pharmacopoeia	pharmacopoeia	NOUN
admet-346	4	16	are	be	AUX
admet-346	4	17	not	not	PART
admet-346	4	18	thoroughly	thoroughly	ADV
admet-346	4	19	suitable	suitable	ADJ
admet-346	4	20	.	.	PUNCT
admet-346	5	1	therefore	therefore	ADV
admet-346	5	2	,	,	PUNCT
admet-346	5	3	we	we	PRON
admet-346	5	4	carried	carry	VERB
admet-346	5	5	out	out	ADP
admet-346	5	6	solubility	solubility	NOUN
admet-346	5	7	and	and	CCONJ
admet-346	5	8	dissolution	dissolution	NOUN
admet-346	5	9	tests	test	NOUN
admet-346	5	10	in	in	ADP
admet-346	5	11	biorelevant	biorelevant	ADJ
admet-346	5	12	media	medium	NOUN
admet-346	5	13	and	and	CCONJ
admet-346	5	14	we	we	PRON
admet-346	5	15	compared	compare	VERB
admet-346	5	16	the	the	DET
admet-346	5	17	results	result	NOUN
admet-346	5	18	with	with	ADP
admet-346	5	19	data	datum	NOUN
admet-346	5	20	measured	measure	VERB
admet-346	5	21	in	in	ADP
admet-346	5	22	compendial	compendial	ADJ
admet-346	5	23	dissolution	dissolution	NOUN
admet-346	5	24	media	medium	NOUN
admet-346	5	25	.	.	PUNCT
admet-346	6	1	a	a	DET
admet-346	6	2	shake	shake	NOUN
admet-346	6	3	-	-	PUNCT
admet-346	6	4	flask	flask	NOUN
admet-346	6	5	method	method	NOUN
admet-346	6	6	and	and	CCONJ
admet-346	6	7	standard	standard	ADJ
admet-346	6	8	paddle	paddle	NOUN
admet-346	6	9	apparatus	apparatus	NOUN
admet-346	6	10	were	be	AUX
admet-346	6	11	used	use	VERB
admet-346	6	12	.	.	PUNCT
admet-346	7	1	the	the	DET
admet-346	7	2	concentration	concentration	NOUN
admet-346	7	3	was	be	AUX
admet-346	7	4	measured	measure	VERB
admet-346	7	5	by	by	ADP
admet-346	7	6	a	a	DET
admet-346	7	7	uv	uv	NOUN
admet-346	7	8	-	-	PUNCT
admet-346	7	9	vis	vis	X
admet-346	7	10	spectrophotometer	spectrophotometer	NOUN
admet-346	7	11	.	.	PUNCT
admet-346	8	1	an	an	DET
admet-346	8	2	oral	oral	ADJ
admet-346	8	3	solid	solid	ADJ
admet-346	8	4	dosage	dosage	NOUN
admet-346	8	5	form	form	NOUN
admet-346	8	6	with	with	ADP
admet-346	8	7	poorly	poorly	ADV
admet-346	8	8	soluble	soluble	ADJ
admet-346	8	9	drug	drug	NOUN
admet-346	8	10	candesartan	candesartan	PROPN
admet-346	8	11	cilexetil	cilexetil	PROPN
admet-346	8	12	was	be	AUX
admet-346	8	13	tested	test	VERB
admet-346	8	14	.	.	PUNCT
admet-346	9	1	significant	significant	ADJ
admet-346	9	2	differences	difference	NOUN
admet-346	9	3	in	in	ADP
admet-346	9	4	the	the	DET
admet-346	9	5	solubility	solubility	NOUN
admet-346	9	6	and	and	CCONJ
admet-346	9	7	dissolution	dissolution	ADJ
admet-346	9	8	profiles	profile	NOUN
admet-346	9	9	of	of	ADP
admet-346	9	10	candesartan	candesartan	PROPN
admet-346	9	11	cilexetil	cilexetil	PROPN
admet-346	9	12	were	be	AUX
admet-346	9	13	observed	observe	VERB
admet-346	9	14	.	.	PUNCT
admet-346	10	1	the	the	DET
admet-346	10	2	study	study	NOUN
admet-346	10	3	offers	offer	VERB
admet-346	10	4	the	the	DET
admet-346	10	5	overview	overview	NOUN
admet-346	10	6	of	of	ADP
admet-346	10	7	compendial	compendial	ADJ
admet-346	10	8	and	and	CCONJ
admet-346	10	9	biorelevant	biorelevant	ADJ
admet-346	10	10	media	medium	NOUN
admet-346	10	11	simulating	simulate	VERB
admet-346	10	12	fasted	fast	VERB
admet-346	10	13	state	state	NOUN
admet-346	10	14	that	that	PRON
admet-346	10	15	can	can	AUX
admet-346	10	16	be	be	AUX
admet-346	10	17	analyzed	analyze	VERB
admet-346	10	18	by	by	ADP
admet-346	10	19	a	a	DET
admet-346	10	20	spectrophotometric	spectrophotometric	ADJ
admet-346	10	21	technique	technique	NOUN
admet-346	10	22	.	.	PUNCT
admet-346	11	1	keywords	keyword	VERB
admet-346	11	2	dissolution	dissolution	ADJ
admet-346	11	3	test	test	NOUN
admet-346	11	4	;	;	PUNCT
admet-346	11	5	compendial	compendial	ADJ
admet-346	11	6	medium	medium	NOUN
admet-346	11	7	;	;	PUNCT
admet-346	11	8	biorelevant	biorelevant	NOUN
admet-346	11	9	medium	medium	NOUN
admet-346	11	10	;	;	PUNCT
admet-346	11	11	fasted	fast	VERB
admet-346	11	12	state	state	NOUN
admet-346	11	13	;	;	PUNCT
admet-346	11	14	poorly	poorly	ADV
admet-346	11	15	soluble	soluble	ADJ
admet-346	11	16	drug	drug	NOUN
admet-346	11	17	;	;	PUNCT
admet-346	11	18	candesartan	candesartan	PROPN
admet-346	11	19	cilexetil	cilexetil	PROPN
admet-346	11	20	.	.	PUNCT
admet-346	12	1	introduction	introduction	NOUN
admet-346	12	2	during	during	ADP
admet-346	12	3	a	a	DET
admet-346	12	4	drug	drug	NOUN
admet-346	12	5	dosage	dosage	NOUN
admet-346	12	6	form	form	NOUN
admet-346	12	7	development	development	NOUN
admet-346	12	8	it	it	PRON
admet-346	12	9	is	be	AUX
admet-346	12	10	essential	essential	ADJ
admet-346	12	11	to	to	PART
admet-346	12	12	investigate	investigate	VERB
admet-346	12	13	factors	factor	NOUN
admet-346	12	14	which	which	PRON
admet-346	12	15	influence	influence	VERB
admet-346	12	16	drug	drug	NOUN
admet-346	12	17	absorption	absorption	NOUN
admet-346	12	18	,	,	PUNCT
admet-346	12	19	especially	especially	ADV
admet-346	12	20	after	after	ADP
admet-346	12	21	oral	oral	ADJ
admet-346	12	22	administration	administration	NOUN
admet-346	12	23	.	.	PUNCT
admet-346	13	1	the	the	DET
admet-346	13	2	prediction	prediction	NOUN
admet-346	13	3	of	of	ADP
admet-346	13	4	limiting	limit	VERB
admet-346	13	5	factors	factor	NOUN
admet-346	13	6	can	can	AUX
admet-346	13	7	be	be	AUX
admet-346	13	8	facilitated	facilitate	VERB
admet-346	13	9	by	by	ADP
admet-346	13	10	in	in	ADP
admet-346	13	11	vitro	vitro	X
admet-346	13	12	tests	test	NOUN
admet-346	13	13	[	[	X
admet-346	13	14	1	1	NUM
admet-346	13	15	]	]	PUNCT
admet-346	13	16	.	.	PUNCT
admet-346	14	1	in	in	ADP
admet-346	14	2	vitro	vitro	X
admet-346	14	3	dissolution	dissolution	NOUN
admet-346	14	4	tests	test	NOUN
admet-346	14	5	should	should	AUX
admet-346	14	6	mimic	mimic	VERB
admet-346	14	7	a	a	DET
admet-346	14	8	drug	drug	NOUN
admet-346	14	9	performance	performance	NOUN
admet-346	14	10	in	in	ADP
admet-346	14	11	a	a	DET
admet-346	14	12	human	human	ADJ
admet-346	14	13	proximal	proximal	ADJ
admet-346	14	14	gastrointestinal	gastrointestinal	ADJ
admet-346	14	15	tract	tract	NOUN
admet-346	14	16	(	(	PUNCT
admet-346	14	17	git	git	NOUN
admet-346	14	18	)	)	PUNCT
admet-346	14	19	.	.	PUNCT
admet-346	15	1	to	to	PART
admet-346	15	2	establish	establish	VERB
admet-346	15	3	reliable	reliable	ADJ
admet-346	15	4	in	in	ADP
admet-346	15	5	vitro	vitro	X
admet-346	15	6	testing	test	VERB
admet-346	15	7	it	it	PRON
admet-346	15	8	is	be	AUX
admet-346	15	9	important	important	ADJ
admet-346	15	10	that	that	SCONJ
admet-346	15	11	artificial	artificial	ADJ
admet-346	15	12	environments	environment	NOUN
admet-346	15	13	simulate	simulate	VERB
admet-346	15	14	physiological	physiological	ADJ
admet-346	15	15	conditions	condition	NOUN
admet-346	15	16	as	as	ADV
admet-346	15	17	closely	closely	ADV
admet-346	15	18	as	as	ADP
admet-346	15	19	possible	possible	ADJ
admet-346	15	20	.	.	PUNCT
admet-346	16	1	the	the	DET
admet-346	16	2	level	level	NOUN
admet-346	16	3	of	of	ADP
admet-346	16	4	the	the	DET
admet-346	16	5	simulation	simulation	NOUN
admet-346	16	6	is	be	AUX
admet-346	16	7	dependent	dependent	ADJ
admet-346	16	8	on	on	ADP
admet-346	16	9	many	many	ADJ
admet-346	16	10	factors	factor	NOUN
admet-346	16	11	related	relate	VERB
admet-346	16	12	to	to	ADP
admet-346	16	13	used	use	VERB
admet-346	16	14	equipment	equipment	NOUN
admet-346	16	15	and	and	CCONJ
admet-346	16	16	medium	medium	NOUN
admet-346	16	17	.	.	PUNCT
admet-346	17	1	a	a	DET
admet-346	17	2	physiological	physiological	ADJ
admet-346	17	3	relevant	relevant	ADJ
admet-346	17	4	dissolution	dissolution	NOUN
admet-346	17	5	medium	medium	NOUN
admet-346	17	6	is	be	AUX
admet-346	17	7	great	great	ADJ
admet-346	17	8	contribution	contribution	NOUN
admet-346	17	9	to	to	PART
admet-346	17	10	in	in	X
admet-346	17	11	vitro	vitro	X
admet-346	17	12	dissolution	dissolution	NOUN
admet-346	17	13	tests	test	NOUN
admet-346	17	14	[	[	X
admet-346	17	15	2	2	NUM
admet-346	17	16	]	]	PUNCT
admet-346	17	17	.	.	PUNCT
admet-346	18	1	dissolution	dissolution	PROPN
admet-346	18	2	media	medium	NOUN
admet-346	18	3	were	be	AUX
admet-346	18	4	initially	initially	ADV
admet-346	18	5	intended	intend	VERB
admet-346	18	6	mainly	mainly	ADV
admet-346	18	7	for	for	ADP
admet-346	18	8	quality	quality	NOUN
admet-346	18	9	control	control	NOUN
admet-346	18	10	purposes	purpose	NOUN
admet-346	18	11	and	and	CCONJ
admet-346	18	12	water	water	NOUN
admet-346	18	13	was	be	AUX
admet-346	18	14	frequently	frequently	ADV
admet-346	18	15	used	use	VERB
admet-346	18	16	as	as	ADP
admet-346	18	17	the	the	DET
admet-346	18	18	dissolution	dissolution	PROPN
admet-346	18	19	medium	medium	NOUN
admet-346	18	20	.	.	PUNCT
admet-346	19	1	however	however	ADV
admet-346	19	2	,	,	PUNCT
admet-346	19	3	later	later	ADV
admet-346	19	4	approach	approach	NOUN
admet-346	19	5	led	lead	VERB
admet-346	19	6	to	to	ADP
admet-346	19	7	the	the	DET
admet-346	19	8	development	development	NOUN
admet-346	19	9	of	of	ADP
admet-346	19	10	new	new	ADJ
admet-346	19	11	media	medium	NOUN
admet-346	19	12	which	which	PRON
admet-346	19	13	resemble	resemble	VERB
admet-346	19	14	gastrointestinal	gastrointestinal	ADJ
admet-346	19	15	fluids	fluid	NOUN
admet-346	19	16	.	.	PUNCT
admet-346	20	1	simulated	simulate	VERB
admet-346	20	2	gastric	gastric	ADJ
admet-346	20	3	fluid	fluid	NOUN
admet-346	20	4	(	(	PUNCT
admet-346	20	5	sgf	sgf	NOUN
admet-346	20	6	)	)	PUNCT
admet-346	20	7	and	and	CCONJ
admet-346	20	8	simulated	simulate	VERB
admet-346	20	9	intestinal	intestinal	ADJ
admet-346	20	10	fluid	fluid	NOUN
admet-346	20	11	(	(	PUNCT
admet-346	20	12	sif	sif	NOUN
admet-346	20	13	)	)	PUNCT
admet-346	20	14	were	be	AUX
admet-346	20	15	the	the	DET
admet-346	20	16	first	first	ADJ
admet-346	20	17	proposals	proposal	NOUN
admet-346	20	18	[	[	X
admet-346	20	19	3	3	NUM
admet-346	20	20	]	]	PUNCT
admet-346	20	21	.	.	PUNCT
admet-346	21	1	both	both	DET
admet-346	21	2	artificial	artificial	ADJ
admet-346	21	3	fluids	fluid	NOUN
admet-346	21	4	are	be	AUX
admet-346	21	5	described	describe	VERB
admet-346	21	6	in	in	ADP
admet-346	21	7	the	the	DET
admet-346	21	8	international	international	ADJ
admet-346	21	9	pharmacopoeias	pharmacopoeia	NOUN
admet-346	21	10	.	.	PUNCT
admet-346	22	1	these	these	DET
admet-346	22	2	media	medium	NOUN
admet-346	22	3	reflect	reflect	VERB
admet-346	22	4	roughly	roughly	ADV
admet-346	22	5	ph	ph	ADJ
admet-346	22	6	conditions	condition	NOUN
admet-346	22	7	and	and	CCONJ
admet-346	22	8	the	the	DET
admet-346	22	9	enzyme	enzyme	NOUN
admet-346	22	10	activity	activity	NOUN
admet-346	22	11	in	in	ADP
admet-346	22	12	the	the	DET
admet-346	22	13	stomach	stomach	NOUN
admet-346	22	14	(	(	PUNCT
admet-346	22	15	sgf	sgf	PROPN
admet-346	22	16	contains	contain	VERB
admet-346	22	17	pepsin	pepsin	NOUN
admet-346	22	18	,	,	PUNCT
admet-346	22	19	ph	ph	NOUN
admet-346	22	20	1.2	1.2	NUM
admet-346	22	21	)	)	PUNCT
admet-346	22	22	and	and	CCONJ
admet-346	22	23	small	small	ADJ
admet-346	22	24	intestinal	intestinal	ADJ
admet-346	22	25	(	(	PUNCT
admet-346	22	26	sif	sif	PROPN
admet-346	22	27	contains	contain	VERB
admet-346	22	28	pancreatin	pancreatin	ADJ
admet-346	22	29	,	,	PUNCT
admet-346	22	30	ph	ph	ADJ
admet-346	22	31	6.8	6.8	NUM
admet-346	22	32	)	)	PUNCT
admet-346	22	33	.	.	PUNCT
admet-346	23	1	nevertheless	nevertheless	ADV
admet-346	23	2	,	,	PUNCT
admet-346	23	3	there	there	PRON
admet-346	23	4	are	be	VERB
admet-346	23	5	variants	variant	NOUN
admet-346	23	6	without	without	ADP
admet-346	23	7	enzymes	enzyme	NOUN
admet-346	23	8	–	–	PUNCT
admet-346	23	9	sgfsp	sgfsp	NOUN
admet-346	23	10	(	(	PUNCT
admet-346	23	11	sine	sine	ADJ
admet-346	23	12	pepsin	pepsin	NOUN
admet-346	23	13	)	)	PUNCT
admet-346	23	14	and	and	CCONJ
admet-346	23	15	sifsp	sifsp	PROPN
admet-346	23	16	(	(	PUNCT
admet-346	23	17	sine	sine	NOUN
admet-346	23	18	pancreatin	pancreatin	ADV
admet-346	23	19	)	)	PUNCT
admet-346	24	1	[	[	X
admet-346	24	2	4	4	NUM
admet-346	24	3	]	]	PUNCT
admet-346	24	4	.	.	PUNCT
admet-346	25	1	sgf	sgf	PROPN
admet-346	25	2	and	and	CCONJ
admet-346	25	3	sif	sif	NOUN
admet-346	25	4	do	do	AUX
admet-346	25	5	not	not	PART
admet-346	25	6	contain	contain	VERB
admet-346	25	7	any	any	DET
admet-346	25	8	surfactants	surfactant	NOUN
admet-346	25	9	,	,	PUNCT
admet-346	25	10	although	although	SCONJ
admet-346	25	11	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-346	25	12	mailto:gruberol@vscht.cz	mailto:gruberol@vscht.cz	NOUN
admet-346	25	13	gruberová	gruberová	PROPN
admet-346	25	14	and	and	CCONJ
admet-346	25	15	kratochvil	kratochvil	PROPN
admet-346	25	16	admet	admet	PROPN
admet-346	25	17	&	&	CCONJ
admet-346	25	18	dmpk	dmpk	PROPN
admet-346	25	19	5(1	5(1	NUM
admet-346	25	20	)	)	PUNCT
admet-346	25	21	(	(	PUNCT
admet-346	25	22	2017	2017	NUM
admet-346	25	23	)	)	PUNCT
admet-346	25	24	39	39	NUM
admet-346	25	25	-	-	SYM
admet-346	25	26	46	46	NUM
admet-346	25	27	40	40	NUM
admet-346	25	28	surfactants	surfactant	NOUN
admet-346	25	29	have	have	AUX
admet-346	25	30	been	be	AUX
admet-346	25	31	commonly	commonly	ADV
admet-346	25	32	used	use	VERB
admet-346	25	33	to	to	PART
admet-346	25	34	improve	improve	VERB
admet-346	25	35	the	the	DET
admet-346	25	36	solubility	solubility	NOUN
admet-346	25	37	of	of	ADP
admet-346	25	38	low	low	ADJ
admet-346	25	39	soluble	soluble	ADJ
admet-346	25	40	drugs	drug	NOUN
admet-346	25	41	.	.	PUNCT
admet-346	26	1	therefore	therefore	ADV
admet-346	26	2	,	,	PUNCT
admet-346	26	3	dressman	dressman	NOUN
admet-346	26	4	et	et	PROPN
admet-346	26	5	al	al	PROPN
admet-346	26	6	.	.	PUNCT
admet-346	27	1	[	[	X
admet-346	27	2	5	5	NUM
admet-346	27	3	]	]	PUNCT
admet-346	27	4	and	and	CCONJ
admet-346	27	5	galia	galia	PROPN
admet-346	27	6	et	et	PROPN
admet-346	27	7	al	al	PROPN
admet-346	27	8	.	.	PUNCT
admet-346	28	1	[	[	X
admet-346	28	2	6	6	NUM
admet-346	28	3	]	]	PUNCT
admet-346	28	4	proposed	propose	VERB
admet-346	28	5	addition	addition	NOUN
admet-346	28	6	of	of	ADP
admet-346	28	7	synthetic	synthetic	ADJ
admet-346	28	8	surfactants	surfactant	NOUN
admet-346	28	9	–	–	PUNCT
admet-346	28	10	triton	triton	PROPN
admet-346	28	11	x	x	SYM
admet-346	28	12	®	®	PROPN
admet-346	28	13	-100	-100	PROPN
admet-346	28	14	(	(	PUNCT
admet-346	28	15	sgftriton	sgftriton	PROPN
admet-346	28	16	)	)	PUNCT
admet-346	28	17	and	and	CCONJ
admet-346	28	18	sodium	sodium	NOUN
admet-346	28	19	lauryl	lauryl	NOUN
admet-346	28	20	sulfate	sulfate	NOUN
admet-346	28	21	(	(	PUNCT
admet-346	28	22	sgfsls	sgfsls	NOUN
admet-346	28	23	)	)	PUNCT
admet-346	28	24	.	.	PUNCT
admet-346	29	1	these	these	DET
admet-346	29	2	media	medium	NOUN
admet-346	29	3	induced	induce	VERB
admet-346	29	4	better	well	ADJ
admet-346	29	5	solubility	solubility	NOUN
admet-346	29	6	of	of	ADP
admet-346	29	7	low	low	ADJ
admet-346	29	8	soluble	soluble	ADJ
admet-346	29	9	compounds	compound	NOUN
admet-346	29	10	but	but	CCONJ
admet-346	29	11	on	on	ADP
admet-346	29	12	the	the	DET
admet-346	29	13	other	other	ADJ
admet-346	29	14	hand	hand	NOUN
admet-346	29	15	they	they	PRON
admet-346	29	16	were	be	AUX
admet-346	29	17	not	not	PART
admet-346	29	18	physiologically	physiologically	ADV
admet-346	29	19	relevant	relevant	ADJ
admet-346	29	20	[	[	X
admet-346	29	21	7	7	NUM
admet-346	29	22	]	]	PUNCT
admet-346	29	23	.	.	PUNCT
admet-346	30	1	although	although	SCONJ
admet-346	30	2	the	the	DET
admet-346	30	3	composition	composition	NOUN
admet-346	30	4	of	of	ADP
admet-346	30	5	artificial	artificial	ADJ
admet-346	30	6	fluids	fluid	NOUN
admet-346	30	7	reflects	reflect	VERB
admet-346	30	8	specific	specific	ADJ
admet-346	30	9	parameters	parameter	NOUN
admet-346	30	10	of	of	ADP
admet-346	30	11	git	git	NOUN
admet-346	30	12	physiology	physiology	NOUN
admet-346	30	13	,	,	PUNCT
admet-346	30	14	they	they	PRON
admet-346	30	15	are	be	AUX
admet-346	30	16	not	not	PART
admet-346	30	17	adequate	adequate	ADJ
admet-346	30	18	models	model	NOUN
admet-346	30	19	of	of	ADP
admet-346	30	20	in	in	ADP
admet-346	30	21	vivo	vivo	ADJ
admet-346	30	22	conditions	condition	NOUN
admet-346	30	23	[	[	X
admet-346	30	24	2	2	NUM
admet-346	30	25	]	]	PUNCT
admet-346	30	26	.	.	PUNCT
admet-346	31	1	thus	thus	ADV
admet-346	31	2	,	,	PUNCT
admet-346	31	3	fasted	fast	VERB
admet-346	31	4	state	state	NOUN
admet-346	31	5	simulated	simulate	VERB
admet-346	31	6	gastric	gastric	ADJ
admet-346	31	7	fluid	fluid	NOUN
admet-346	31	8	(	(	PUNCT
admet-346	31	9	fassgf	fassgf	NOUN
admet-346	31	10	)	)	PUNCT
admet-346	31	11	and	and	CCONJ
admet-346	31	12	fasted	fast	VERB
admet-346	31	13	state	state	NOUN
admet-346	31	14	simulated	simulate	VERB
admet-346	31	15	intestinal	intestinal	ADJ
admet-346	31	16	fluid	fluid	NOUN
admet-346	31	17	(	(	PUNCT
admet-346	31	18	fassif	fassif	NOUN
admet-346	31	19	)	)	PUNCT
admet-346	31	20	have	have	AUX
admet-346	31	21	been	be	AUX
admet-346	31	22	regarded	regard	VERB
admet-346	31	23	as	as	ADP
admet-346	31	24	biorelevant	biorelevant	ADJ
admet-346	31	25	media	medium	NOUN
admet-346	31	26	.	.	PUNCT
admet-346	32	1	fassgf	fassgf	PROPN
admet-346	32	2	was	be	AUX
admet-346	32	3	proposed	propose	VERB
admet-346	32	4	by	by	ADP
admet-346	32	5	vertzoni	vertzoni	PROPN
admet-346	32	6	et	et	PROPN
admet-346	32	7	al	al	PROPN
admet-346	32	8	.	.	PROPN
admet-346	33	1	in	in	ADP
admet-346	33	2	2005	2005	NUM
admet-346	33	3	[	[	X
admet-346	33	4	8	8	NUM
admet-346	33	5	]	]	PUNCT
admet-346	33	6	and	and	CCONJ
admet-346	33	7	fassif	fassif	NOUN
admet-346	33	8	by	by	ADP
admet-346	33	9	galia	galia	PROPN
admet-346	33	10	at	at	ADP
admet-346	33	11	al	al	PROPN
admet-346	33	12	.	.	PUNCT
admet-346	34	1	in	in	ADP
admet-346	34	2	1998	1998	NUM
admet-346	34	3	[	[	X
admet-346	34	4	4	4	NUM
admet-346	34	5	]	]	PUNCT
admet-346	34	6	.	.	PUNCT
admet-346	35	1	both	both	DET
admet-346	35	2	biorelevant	biorelevant	ADJ
admet-346	35	3	media	medium	NOUN
admet-346	35	4	contain	contain	VERB
admet-346	35	5	natural	natural	ADJ
admet-346	35	6	surfactants	surfactant	NOUN
admet-346	35	7	:	:	PUNCT
admet-346	35	8	taurocholate	taurocholate	NOUN
admet-346	35	9	sodium	sodium	NOUN
admet-346	35	10	,	,	PUNCT
admet-346	35	11	which	which	PRON
admet-346	35	12	represents	represent	VERB
admet-346	35	13	bile	bile	NOUN
admet-346	35	14	salts	salt	NOUN
admet-346	35	15	,	,	PUNCT
admet-346	35	16	and	and	CCONJ
admet-346	35	17	lecithin	lecithin	NOUN
admet-346	35	18	.	.	PUNCT
admet-346	36	1	the	the	DET
admet-346	36	2	medium	medium	ADJ
admet-346	36	3	fassgf	fassgf	NOUN
admet-346	36	4	comprises	comprise	VERB
admet-346	36	5	the	the	DET
admet-346	36	6	enzyme	enzyme	NOUN
admet-346	36	7	pepsin	pepsin	NOUN
admet-346	36	8	as	as	SCONJ
admet-346	36	9	the	the	DET
admet-346	36	10	medium	medium	ADJ
admet-346	36	11	sgf	sgf	NOUN
admet-346	36	12	but	but	CCONJ
admet-346	36	13	pepsin	pepsin	NOUN
admet-346	36	14	is	be	AUX
admet-346	36	15	contained	contain	VERB
admet-346	36	16	in	in	ADP
admet-346	36	17	very	very	ADV
admet-346	36	18	low	low	ADJ
admet-346	36	19	concentration	concentration	NOUN
admet-346	36	20	in	in	ADP
admet-346	36	21	fassgf	fassgf	NOUN
admet-346	36	22	.	.	PUNCT
admet-346	37	1	unlike	unlike	ADP
admet-346	37	2	sif	sif	PROPN
admet-346	37	3	,	,	PUNCT
admet-346	37	4	fassif	fassif	NOUN
admet-346	37	5	does	do	AUX
admet-346	37	6	not	not	PART
admet-346	37	7	comprise	comprise	VERB
admet-346	37	8	the	the	DET
admet-346	37	9	enzyme	enzyme	NOUN
admet-346	37	10	pancreatin	pancreatin	ADJ
admet-346	37	11	.	.	PUNCT
admet-346	38	1	all	all	DET
admet-346	38	2	reported	report	VERB
admet-346	38	3	media	medium	NOUN
admet-346	38	4	were	be	AUX
admet-346	38	5	developed	develop	VERB
admet-346	38	6	for	for	ADP
admet-346	38	7	the	the	DET
admet-346	38	8	simulation	simulation	NOUN
admet-346	38	9	of	of	ADP
admet-346	38	10	fasting	fast	VERB
admet-346	38	11	conditions	condition	NOUN
admet-346	38	12	in	in	ADP
admet-346	38	13	the	the	DET
admet-346	38	14	upper	upper	ADJ
admet-346	38	15	git	git	NOUN
admet-346	38	16	.	.	PUNCT
admet-346	39	1	media	medium	NOUN
admet-346	39	2	simulating	simulate	VERB
admet-346	39	3	fed	fed	PROPN
admet-346	39	4	state	state	NOUN
admet-346	39	5	of	of	ADP
admet-346	39	6	stomach	stomach	NOUN
admet-346	39	7	(	(	PUNCT
admet-346	39	8	fed	feed	VERB
admet-346	39	9	state	state	NOUN
admet-346	39	10	simulated	simulate	VERB
admet-346	39	11	gastric	gastric	ADJ
admet-346	39	12	fluid	fluid	NOUN
admet-346	39	13	,	,	PUNCT
admet-346	39	14	fessgf	fessgf	NOUN
admet-346	39	15	)	)	PUNCT
admet-346	39	16	and	and	CCONJ
admet-346	39	17	small	small	ADJ
admet-346	39	18	intestine	intestine	NOUN
admet-346	39	19	(	(	PUNCT
admet-346	39	20	fed	feed	VERB
admet-346	39	21	state	state	NOUN
admet-346	39	22	simulated	simulate	VERB
admet-346	39	23	intestine	intestine	NOUN
admet-346	39	24	fluid	fluid	NOUN
admet-346	39	25	,	,	PUNCT
admet-346	39	26	fessif	fessif	NOUN
admet-346	39	27	)	)	PUNCT
admet-346	39	28	have	have	AUX
admet-346	39	29	been	be	AUX
admet-346	39	30	also	also	ADV
admet-346	39	31	developed	develop	VERB
admet-346	39	32	.	.	PUNCT
admet-346	40	1	former	former	ADJ
admet-346	40	2	researches	research	VERB
admet-346	40	3	about	about	ADP
admet-346	40	4	the	the	DET
admet-346	40	5	simulation	simulation	NOUN
admet-346	40	6	of	of	ADP
admet-346	40	7	postprandial	postprandial	ADJ
admet-346	40	8	gastric	gastric	ADJ
admet-346	40	9	conditions	condition	NOUN
admet-346	40	10	tested	test	VERB
admet-346	40	11	homogenized	homogenize	VERB
admet-346	40	12	breakfasts	breakfast	NOUN
admet-346	40	13	with	with	ADP
admet-346	40	14	milk	milk	NOUN
admet-346	40	15	and	and	CCONJ
admet-346	40	16	nutrition	nutrition	NOUN
admet-346	40	17	products	product	NOUN
admet-346	40	18	[	[	X
admet-346	40	19	2	2	NUM
admet-346	40	20	]	]	PUNCT
admet-346	40	21	.	.	PUNCT
admet-346	41	1	the	the	DET
admet-346	41	2	first	first	ADJ
admet-346	41	3	proposal	proposal	NOUN
admet-346	41	4	of	of	ADP
admet-346	41	5	fessif	fessif	NOUN
admet-346	41	6	was	be	AUX
admet-346	41	7	published	publish	VERB
admet-346	41	8	by	by	ADP
admet-346	41	9	galia	galia	PROPN
admet-346	41	10	at	at	ADP
admet-346	41	11	al	al	PROPN
admet-346	41	12	.	.	PUNCT
admet-346	42	1	in	in	ADP
admet-346	42	2	1998	1998	NUM
admet-346	42	3	[	[	X
admet-346	42	4	4	4	NUM
admet-346	42	5	]	]	PUNCT
admet-346	42	6	.	.	PUNCT
admet-346	43	1	updates	update	VERB
admet-346	43	2	media	medium	NOUN
admet-346	43	3	(	(	PUNCT
admet-346	43	4	snapshot	snapshot	ADJ
admet-346	43	5	media	medium	NOUN
admet-346	43	6	)	)	PUNCT
admet-346	43	7	were	be	AUX
admet-346	43	8	proposed	propose	VERB
admet-346	43	9	by	by	ADP
admet-346	43	10	jantratid	jantratid	PROPN
admet-346	43	11	et	et	PROPN
admet-346	43	12	al	al	PROPN
admet-346	43	13	.	.	PROPN
admet-346	44	1	in	in	ADP
admet-346	44	2	2008	2008	NUM
admet-346	44	3	[	[	X
admet-346	44	4	9	9	NUM
admet-346	44	5	]	]	PUNCT
admet-346	44	6	.	.	PUNCT
admet-346	45	1	however	however	ADV
admet-346	45	2	,	,	PUNCT
admet-346	45	3	this	this	DET
admet-346	45	4	study	study	NOUN
admet-346	45	5	is	be	AUX
admet-346	45	6	not	not	PART
admet-346	45	7	interested	interested	ADJ
admet-346	45	8	in	in	ADP
admet-346	45	9	fed	fed	PROPN
admet-346	45	10	state	state	NOUN
admet-346	45	11	media	medium	NOUN
admet-346	45	12	since	since	SCONJ
admet-346	45	13	their	their	PRON
admet-346	45	14	composition	composition	NOUN
admet-346	45	15	hinders	hinder	VERB
admet-346	45	16	direct	direct	ADJ
admet-346	45	17	spectrophotometric	spectrophotometric	ADJ
admet-346	45	18	analysis	analysis	NOUN
admet-346	45	19	.	.	PUNCT
admet-346	46	1	the	the	DET
admet-346	46	2	biorelevant	biorelevant	ADJ
admet-346	46	3	dissolution	dissolution	NOUN
admet-346	46	4	properties	property	NOUN
admet-346	46	5	of	of	ADP
admet-346	46	6	many	many	ADJ
admet-346	46	7	drugs	drug	NOUN
admet-346	46	8	have	have	AUX
admet-346	46	9	been	be	AUX
admet-346	46	10	studied	study	VERB
admet-346	46	11	since	since	SCONJ
admet-346	46	12	the	the	DET
admet-346	46	13	beginning	beginning	NOUN
admet-346	46	14	of	of	ADP
admet-346	46	15	biorelevant	biorelevant	ADJ
admet-346	46	16	media	medium	NOUN
admet-346	46	17	development	development	NOUN
admet-346	46	18	.	.	PUNCT
admet-346	47	1	studies	study	NOUN
admet-346	47	2	of	of	ADP
admet-346	47	3	solubility	solubility	NOUN
admet-346	47	4	in	in	ADP
admet-346	47	5	biorelevant	biorelevant	ADJ
admet-346	47	6	media	medium	NOUN
admet-346	47	7	were	be	AUX
admet-346	47	8	carried	carry	VERB
admet-346	47	9	out	out	ADP
admet-346	47	10	to	to	PART
admet-346	47	11	predict	predict	VERB
admet-346	47	12	bioavailability	bioavailability	NOUN
admet-346	47	13	particularly	particularly	ADV
admet-346	47	14	of	of	ADP
admet-346	47	15	ionisable	ionisable	ADJ
admet-346	47	16	molecules	molecule	NOUN
admet-346	47	17	since	since	SCONJ
admet-346	47	18	the	the	DET
admet-346	47	19	solubility	solubility	NOUN
admet-346	47	20	of	of	ADP
admet-346	47	21	ionisable	ionisable	ADJ
admet-346	47	22	compounds	compound	NOUN
admet-346	47	23	depends	depend	VERB
admet-346	47	24	on	on	ADP
admet-346	47	25	their	their	PRON
admet-346	47	26	pka	pka	NOUN
admet-346	47	27	and	and	CCONJ
admet-346	47	28	ph	ph	NOUN
admet-346	47	29	of	of	ADP
admet-346	47	30	the	the	DET
admet-346	47	31	media	medium	NOUN
admet-346	48	1	[	[	X
admet-346	48	2	10	10	NUM
admet-346	48	3	]	]	PUNCT
admet-346	48	4	.	.	PUNCT
admet-346	49	1	the	the	DET
admet-346	49	2	solubilizing	solubilize	VERB
admet-346	49	3	effect	effect	NOUN
admet-346	49	4	of	of	ADP
admet-346	49	5	bile	bile	NOUN
admet-346	49	6	salts	salt	NOUN
admet-346	49	7	,	,	PUNCT
admet-346	49	8	lecithin	lecithin	NOUN
admet-346	49	9	and	and	CCONJ
admet-346	49	10	other	other	ADJ
admet-346	49	11	food	food	NOUN
admet-346	49	12	effects	effect	NOUN
admet-346	49	13	on	on	ADP
admet-346	49	14	drug	drug	NOUN
admet-346	49	15	solubilization	solubilization	NOUN
admet-346	49	16	were	be	AUX
admet-346	49	17	tested	test	VERB
admet-346	49	18	for	for	ADP
admet-346	49	19	instance	instance	NOUN
admet-346	49	20	by	by	ADP
admet-346	49	21	takács	takács	PROPN
admet-346	49	22	-	-	PUNCT
admet-346	49	23	novák	novák	NOUN
admet-346	49	24	et	et	PROPN
admet-346	49	25	al	al	PROPN
admet-346	49	26	.	.	PUNCT
admet-346	50	1	[	[	X
admet-346	50	2	10	10	NUM
admet-346	50	3	]	]	PUNCT
admet-346	50	4	,	,	PUNCT
admet-346	50	5	frank	frank	PROPN
admet-346	50	6	et	et	PROPN
admet-346	50	7	al	al	PROPN
admet-346	50	8	.	.	PUNCT
admet-346	51	1	[	[	X
admet-346	51	2	11	11	NUM
admet-346	51	3	]	]	PUNCT
admet-346	51	4	,	,	PUNCT
admet-346	51	5	dressman	dressman	NOUN
admet-346	51	6	at	at	ADP
admet-346	51	7	al	al	PROPN
admet-346	51	8	.	.	PUNCT
admet-346	52	1	[	[	X
admet-346	52	2	12	12	NUM
admet-346	52	3	]	]	PUNCT
admet-346	52	4	,	,	PUNCT
admet-346	52	5	and	and	CCONJ
admet-346	52	6	kostewicz	kostewicz	VERB
admet-346	52	7	et	et	PROPN
admet-346	52	8	al	al	PROPN
admet-346	52	9	.	.	PUNCT
admet-346	53	1	[	[	X
admet-346	53	2	13	13	NUM
admet-346	53	3	]	]	PUNCT
admet-346	53	4	.	.	PUNCT
admet-346	54	1	figure	figure	NOUN
admet-346	54	2	1	1	NUM
admet-346	54	3	.	.	PUNCT
admet-346	55	1	structure	structure	NOUN
admet-346	55	2	of	of	ADP
admet-346	55	3	candesartan	candesartan	PROPN
admet-346	55	4	cilexetil	cilexetil	PROPN
admet-346	55	5	(	(	PUNCT
admet-346	55	6	cc	cc	NOUN
admet-346	55	7	)	)	PUNCT
admet-346	55	8	the	the	DET
admet-346	55	9	precise	precise	ADJ
admet-346	55	10	imitation	imitation	NOUN
admet-346	55	11	of	of	ADP
admet-346	55	12	the	the	DET
admet-346	55	13	in	in	ADP
admet-346	55	14	vivo	vivo	ADJ
admet-346	55	15	conditions	condition	NOUN
admet-346	55	16	is	be	AUX
admet-346	55	17	desirable	desirable	ADJ
admet-346	55	18	particularly	particularly	ADV
admet-346	55	19	for	for	ADP
admet-346	55	20	poorly	poorly	ADV
admet-346	55	21	soluble	soluble	ADJ
admet-346	55	22	drugs	drug	NOUN
admet-346	55	23	.	.	PUNCT
admet-346	56	1	as	as	ADP
admet-346	56	2	a	a	DET
admet-346	56	3	case	case	NOUN
admet-346	56	4	example	example	NOUN
admet-346	56	5	of	of	ADP
admet-346	56	6	poorly	poorly	ADV
admet-346	56	7	soluble	soluble	ADJ
admet-346	56	8	drug	drug	NOUN
admet-346	56	9	candesartan	candesartan	PROPN
admet-346	56	10	cilexetil	cilexetil	PROPN
admet-346	56	11	(	(	PUNCT
admet-346	56	12	figure	figure	NOUN
admet-346	56	13	1	1	NUM
admet-346	56	14	)	)	PUNCT
admet-346	56	15	was	be	AUX
admet-346	56	16	chosen	choose	VERB
admet-346	56	17	which	which	PRON
admet-346	56	18	is	be	AUX
admet-346	56	19	practically	practically	ADV
admet-346	56	20	insoluble	insoluble	ADJ
admet-346	56	21	in	in	ADP
admet-346	56	22	water	water	NOUN
admet-346	56	23	(	(	PUNCT
admet-346	56	24	less	less	ADJ
admet-346	56	25	than	than	ADP
admet-346	56	26	0.05	0.05	NUM
admet-346	56	27	µg	µg	NOUN
admet-346	56	28	/	/	SYM
admet-346	56	29	ml	ml	NOUN
admet-346	57	1	[	[	X
admet-346	57	2	14	14	NUM
admet-346	57	3	]	]	SYM
admet-346	57	4	)	)	PUNCT
admet-346	57	5	.	.	PUNCT
admet-346	58	1	as	as	SCONJ
admet-346	58	2	prodrug	prodrug	NOUN
admet-346	58	3	,	,	PUNCT
admet-346	58	4	candesartan	candesartan	PROPN
admet-346	58	5	cilexetil	cilexetil	PROPN
admet-346	58	6	(	(	PUNCT
admet-346	58	7	cc	cc	NOUN
admet-346	58	8	)	)	PUNCT
admet-346	58	9	is	be	AUX
admet-346	58	10	completely	completely	ADV
admet-346	58	11	bioactivated	bioactivate	VERB
admet-346	58	12	by	by	ADP
admet-346	58	13	ester	ester	NOUN
admet-346	58	14	hydrolysis	hydrolysis	NOUN
admet-346	58	15	to	to	PART
admet-346	58	16	candesartan	candesartan	VERB
admet-346	58	17	during	during	ADP
admet-346	58	18	a	a	DET
admet-346	58	19	gastrointestinal	gastrointestinal	ADJ
admet-346	58	20	absorption	absorption	NOUN
admet-346	58	21	.	.	PUNCT
admet-346	59	1	actually	actually	ADV
admet-346	59	2	,	,	PUNCT
admet-346	59	3	candesartan	candesartan	PROPN
admet-346	59	4	is	be	AUX
admet-346	59	5	an	an	DET
admet-346	59	6	angiotensin	angiotensin	NOUN
admet-346	59	7	ii	ii	NOUN
admet-346	59	8	receptor	receptor	NOUN
admet-346	59	9	antagonist	antagonist	NOUN
admet-346	59	10	and	and	CCONJ
admet-346	59	11	it	it	PRON
admet-346	59	12	is	be	AUX
admet-346	59	13	mainly	mainly	ADV
admet-346	59	14	indicated	indicate	VERB
admet-346	59	15	for	for	ADP
admet-346	59	16	the	the	DET
admet-346	59	17	treatment	treatment	NOUN
admet-346	59	18	of	of	ADP
admet-346	59	19	hypertension	hypertension	NOUN
admet-346	59	20	[	[	X
admet-346	59	21	15	15	NUM
admet-346	59	22	]	]	PUNCT
admet-346	59	23	.	.	PUNCT
admet-346	60	1	however	however	ADV
admet-346	60	2	,	,	PUNCT
admet-346	60	3	cc	cc	PROPN
admet-346	60	4	is	be	AUX
admet-346	60	5	classified	classify	VERB
admet-346	60	6	as	as	SCONJ
admet-346	60	7	bcs	bcs	NOUN
admet-346	60	8	class	class	PROPN
admet-346	60	9	ii	ii	PROPN
admet-346	60	10	drug	drug	NOUN
admet-346	60	11	and	and	CCONJ
admet-346	60	12	its	its	PRON
admet-346	60	13	very	very	ADV
admet-346	60	14	low	low	ADJ
admet-346	60	15	solubility	solubility	NOUN
admet-346	60	16	across	across	ADP
admet-346	60	17	the	the	DET
admet-346	60	18	physiological	physiological	ADJ
admet-346	60	19	ph	ph	NOUN
admet-346	60	20	range	range	NOUN
admet-346	60	21	brings	bring	VERB
admet-346	60	22	about	about	ADP
admet-346	60	23	an	an	DET
admet-346	60	24	incomplete	incomplete	ADJ
admet-346	60	25	absorption	absorption	NOUN
admet-346	60	26	and	and	CCONJ
admet-346	60	27	it	it	PRON
admet-346	60	28	is	be	AUX
admet-346	60	29	a	a	DET
admet-346	60	30	reason	reason	NOUN
admet-346	60	31	for	for	ADP
admet-346	60	32	low	low	ADJ
admet-346	60	33	bioavailability	bioavailability	NOUN
admet-346	60	34	(	(	PUNCT
admet-346	60	35	about	about	ADP
admet-346	60	36	of	of	ADP
admet-346	60	37	15	15	NUM
admet-346	60	38	%	%	NOUN
admet-346	60	39	[	[	X
admet-346	60	40	14	14	NUM
admet-346	60	41	]	]	NUM
admet-346	60	42	)	)	PUNCT
admet-346	60	43	.	.	PUNCT
admet-346	61	1	the	the	DET
admet-346	61	2	compound	compound	NOUN
admet-346	61	3	of	of	ADP
admet-346	61	4	our	our	PRON
admet-346	61	5	interest	interest	NOUN
admet-346	61	6	is	be	AUX
admet-346	61	7	a	a	DET
admet-346	61	8	weak	weak	ADJ
admet-346	61	9	acid	acid	NOUN
admet-346	61	10	(	(	PUNCT
admet-346	61	11	pka	pka	NOUN
admet-346	61	12	6.0	6.0	NUM
admet-346	62	1	[	[	X
admet-346	62	2	16	16	NUM
admet-346	62	3	]	]	PUNCT
admet-346	62	4	)	)	PUNCT
admet-346	62	5	with	with	ADP
admet-346	62	6	lower	low	ADJ
admet-346	62	7	solubility	solubility	NOUN
admet-346	62	8	in	in	ADP
admet-346	62	9	low	low	ADJ
admet-346	62	10	phs	phs	NOUN
admet-346	62	11	due	due	ADP
admet-346	62	12	to	to	ADP
admet-346	62	13	deprotonation	deprotonation	NOUN
admet-346	62	14	of	of	ADP
admet-346	62	15	a	a	DET
admet-346	62	16	tetrazole	tetrazole	NOUN
admet-346	62	17	group	group	NOUN
admet-346	62	18	at	at	ADP
admet-346	62	19	phs	phs	NOUN
admet-346	62	20	higher	high	ADJ
admet-346	62	21	than	than	ADP
admet-346	62	22	6	6	NUM
admet-346	63	1	[	[	SYM
admet-346	63	2	16	16	NUM
admet-346	63	3	]	]	PUNCT
admet-346	63	4	.	.	PUNCT
admet-346	64	1	the	the	DET
admet-346	64	2	results	result	NOUN
admet-346	64	3	from	from	ADP
admet-346	64	4	our	our	PRON
admet-346	64	5	study	study	NOUN
admet-346	64	6	confirm	confirm	VERB
admet-346	64	7	an	an	DET
admet-346	64	8	increase	increase	NOUN
admet-346	64	9	in	in	ADP
admet-346	64	10	cc	cc	NOUN
admet-346	64	11	solubility	solubility	NOUN
admet-346	64	12	with	with	ADP
admet-346	64	13	admet	admet	PROPN
admet-346	64	14	&	&	CCONJ
admet-346	64	15	dmpk	dmpk	PROPN
admet-346	64	16	5(1	5(1	NUM
admet-346	64	17	)	)	PUNCT
admet-346	64	18	(	(	PUNCT
admet-346	64	19	2017	2017	NUM
admet-346	64	20	)	)	PUNCT
admet-346	64	21	39	39	NUM
admet-346	64	22	-	-	SYM
admet-346	64	23	46	46	NUM
admet-346	64	24	biorelevant	biorelevant	NOUN
admet-346	64	25	dissolution	dissolution	NOUN
admet-346	64	26	of	of	ADP
admet-346	64	27	candesartan	candesartan	PROPN
admet-346	64	28	cilexetil	cilexetil	PROPN
admet-346	64	29	doi	doi	PROPN
admet-346	64	30	:	:	PUNCT
admet-346	64	31	10.5599	10.5599	NUM
admet-346	64	32	/	/	SYM
admet-346	64	33	admet.5.1.346	admet.5.1.346	NUM
admet-346	64	34	41	41	NUM
admet-346	64	35	increasing	increase	VERB
admet-346	64	36	ph	ph	NOUN
admet-346	64	37	.	.	PUNCT
admet-346	65	1	moreover	moreover	ADV
admet-346	65	2	,	,	PUNCT
admet-346	65	3	the	the	DET
admet-346	65	4	solubility	solubility	NOUN
admet-346	65	5	of	of	ADP
admet-346	65	6	cc	cc	PROPN
admet-346	65	7	is	be	AUX
admet-346	65	8	enhanced	enhance	VERB
admet-346	65	9	using	use	VERB
admet-346	65	10	surfactant	surfactant	ADJ
admet-346	65	11	tween	tween	NOUN
admet-346	65	12	20	20	NUM
admet-346	65	13	and	and	CCONJ
admet-346	65	14	the	the	DET
admet-346	65	15	surfactant	surfactant	NOUN
admet-346	65	16	is	be	AUX
admet-346	65	17	required	require	VERB
admet-346	65	18	to	to	PART
admet-346	65	19	achieve	achieve	VERB
admet-346	65	20	sink	sink	NOUN
admet-346	65	21	conditions	condition	NOUN
admet-346	65	22	.	.	PUNCT
admet-346	66	1	the	the	DET
admet-346	66	2	dissolution	dissolution	PROPN
admet-346	66	3	testing	testing	NOUN
admet-346	66	4	of	of	ADP
admet-346	66	5	cc	cc	PROPN
admet-346	66	6	for	for	ADP
admet-346	66	7	quality	quality	NOUN
admet-346	66	8	controls	control	NOUN
admet-346	66	9	has	have	AUX
admet-346	66	10	been	be	AUX
admet-346	66	11	standardly	standardly	ADV
admet-346	66	12	carried	carry	VERB
admet-346	66	13	out	out	ADP
admet-346	66	14	in	in	ADP
admet-346	66	15	900	900	NUM
admet-346	66	16	ml	ml	NOUN
admet-346	66	17	of	of	ADP
admet-346	66	18	0.05	0.05	NUM
admet-346	66	19	m	m	NOUN
admet-346	66	20	phosphate	phosphate	NOUN
admet-346	66	21	buffer	buffer	NOUN
admet-346	66	22	(	(	PUNCT
admet-346	66	23	ph	ph	NOUN
admet-346	66	24	6.5	6.5	NUM
admet-346	66	25	)	)	PUNCT
admet-346	66	26	with	with	ADP
admet-346	66	27	0.35	0.35	NUM
admet-346	66	28	%	%	NOUN
admet-346	66	29	or	or	CCONJ
admet-346	66	30	0.7	0.7	NUM
admet-346	66	31	0	0	NUM
admet-346	66	32	%	%	NOUN
admet-346	66	33	(	(	PUNCT
admet-346	66	34	w	w	NOUN
admet-346	66	35	/	/	SYM
admet-346	66	36	w	w	NOUN
admet-346	66	37	)	)	PUNCT
admet-346	66	38	tween	tween	NOUN
admet-346	66	39	20	20	NUM
admet-346	66	40	(	(	PUNCT
admet-346	66	41	shortcut	shortcut	NOUN
admet-346	66	42	ppt20	ppt20	ADJ
admet-346	66	43	)	)	PUNCT
admet-346	66	44	.	.	PUNCT
admet-346	67	1	the	the	DET
admet-346	67	2	amount	amount	NOUN
admet-346	67	3	of	of	ADP
admet-346	67	4	tween	tween	NOUN
admet-346	67	5	20	20	NUM
admet-346	67	6	depends	depend	VERB
admet-346	67	7	on	on	ADP
admet-346	67	8	dosing	dose	VERB
admet-346	67	9	conditions	condition	NOUN
admet-346	67	10	[	[	X
admet-346	67	11	17	17	NUM
admet-346	67	12	]	]	PUNCT
admet-346	67	13	.	.	PUNCT
admet-346	68	1	a	a	DET
admet-346	68	2	big	big	ADJ
admet-346	68	3	challenge	challenge	NOUN
admet-346	68	4	with	with	ADP
admet-346	68	5	cc	cc	PROPN
admet-346	68	6	is	be	AUX
admet-346	68	7	its	its	PRON
admet-346	68	8	low	low	ADJ
admet-346	68	9	stability	stability	NOUN
admet-346	68	10	in	in	ADP
admet-346	68	11	solutions	solution	NOUN
admet-346	68	12	.	.	PUNCT
admet-346	69	1	the	the	DET
admet-346	69	2	most	most	ADV
admet-346	69	3	important	important	ADJ
admet-346	69	4	factors	factor	NOUN
admet-346	69	5	affecting	affect	VERB
admet-346	69	6	the	the	DET
admet-346	69	7	stability	stability	NOUN
admet-346	69	8	of	of	ADP
admet-346	69	9	cc	cc	PROPN
admet-346	69	10	in	in	ADP
admet-346	69	11	solution	solution	NOUN
admet-346	69	12	are	be	AUX
admet-346	69	13	ph	ph	ADJ
admet-346	69	14	and	and	CCONJ
admet-346	69	15	temperature	temperature	NOUN
admet-346	69	16	.	.	PUNCT
admet-346	70	1	hoppe	hoppe	PROPN
admet-346	70	2	and	and	CCONJ
admet-346	70	3	sznitowska	sznitowska	PROPN
admet-346	70	4	[	[	X
admet-346	70	5	18	18	NUM
admet-346	70	6	]	]	PUNCT
admet-346	70	7	found	find	VERB
admet-346	70	8	out	out	ADP
admet-346	70	9	that	that	SCONJ
admet-346	70	10	the	the	DET
admet-346	70	11	degradation	degradation	NOUN
admet-346	70	12	rate	rate	NOUN
admet-346	70	13	of	of	ADP
admet-346	70	14	cc	cc	NOUN
admet-346	70	15	was	be	AUX
admet-346	70	16	faster	fast	ADV
admet-346	70	17	at	at	ADP
admet-346	70	18	elevated	elevated	ADJ
admet-346	70	19	temperatures	temperature	NOUN
admet-346	70	20	and	and	CCONJ
admet-346	70	21	low	low	ADJ
admet-346	70	22	phs	phs	NOUN
admet-346	70	23	.	.	PUNCT
admet-346	71	1	according	accord	VERB
admet-346	71	2	to	to	ADP
admet-346	71	3	their	their	PRON
admet-346	71	4	results	result	NOUN
admet-346	71	5	,	,	PUNCT
admet-346	71	6	the	the	DET
admet-346	71	7	half	half	ADJ
admet-346	71	8	-	-	PUNCT
admet-346	71	9	life	life	NOUN
admet-346	71	10	of	of	ADP
admet-346	71	11	degradation	degradation	NOUN
admet-346	71	12	is	be	AUX
admet-346	71	13	only	only	ADV
admet-346	71	14	35.91	35.91	NUM
admet-346	71	15	hours	hour	NOUN
admet-346	71	16	in	in	ADP
admet-346	71	17	0.1	0.1	NUM
admet-346	71	18	m	m	NOUN
admet-346	71	19	hcl	hcl	PROPN
admet-346	71	20	(	(	PUNCT
admet-346	71	21	ph	ph	NOUN
admet-346	71	22	1.2	1.2	NUM
admet-346	71	23	)	)	PUNCT
admet-346	71	24	and	and	CCONJ
admet-346	71	25	150.7	150.7	NUM
admet-346	71	26	hours	hour	NOUN
admet-346	71	27	in	in	ADP
admet-346	71	28	0.05	0.05	NUM
admet-346	71	29	m	m	NOUN
admet-346	71	30	phosphate	phosphate	NOUN
admet-346	71	31	buffer	buffer	NOUN
admet-346	71	32	(	(	PUNCT
admet-346	71	33	ph	ph	NOUN
admet-346	71	34	6.5	6.5	NUM
admet-346	71	35	)	)	PUNCT
admet-346	71	36	,	,	PUNCT
admet-346	71	37	both	both	CCONJ
admet-346	71	38	at	at	ADP
admet-346	71	39	37	37	NUM
admet-346	71	40	°	°	ADP
admet-346	71	41	c	c	NOUN
admet-346	71	42	and	and	CCONJ
admet-346	71	43	without	without	ADP
admet-346	71	44	surfactants	surfactant	NOUN
admet-346	71	45	[	[	X
admet-346	71	46	18	18	NUM
admet-346	71	47	]	]	PUNCT
admet-346	71	48	.	.	PUNCT
admet-346	72	1	our	our	PRON
admet-346	72	2	aim	aim	NOUN
admet-346	72	3	was	be	AUX
admet-346	72	4	to	to	PART
admet-346	72	5	study	study	VERB
admet-346	72	6	and	and	CCONJ
admet-346	72	7	compare	compare	VERB
admet-346	72	8	the	the	DET
admet-346	72	9	dissolution	dissolution	NOUN
admet-346	72	10	properties	property	NOUN
admet-346	72	11	of	of	ADP
admet-346	72	12	cc	cc	PROPN
admet-346	72	13	in	in	ADP
admet-346	72	14	media	medium	NOUN
admet-346	72	15	simulating	simulate	VERB
admet-346	72	16	the	the	DET
admet-346	72	17	fasted	fasted	ADJ
admet-346	72	18	state	state	NOUN
admet-346	72	19	of	of	ADP
admet-346	72	20	stomach	stomach	NOUN
admet-346	72	21	and	and	CCONJ
admet-346	72	22	small	small	ADJ
admet-346	72	23	intestine	intestine	NOUN
admet-346	72	24	.	.	PUNCT
admet-346	73	1	this	this	DET
admet-346	73	2	paper	paper	NOUN
admet-346	73	3	provides	provide	VERB
admet-346	73	4	the	the	DET
admet-346	73	5	solubility	solubility	NOUN
admet-346	73	6	data	datum	NOUN
admet-346	73	7	and	and	CCONJ
admet-346	73	8	dissolution	dissolution	NOUN
admet-346	73	9	profiles	profile	NOUN
admet-346	73	10	of	of	ADP
admet-346	73	11	cc	cc	PROPN
admet-346	73	12	in	in	ADP
admet-346	73	13	various	various	ADJ
admet-346	73	14	media	medium	NOUN
admet-346	73	15	(	(	PUNCT
admet-346	73	16	artificial	artificial	ADJ
admet-346	73	17	media	medium	NOUN
admet-346	73	18	with	with	ADP
admet-346	73	19	or	or	CCONJ
admet-346	73	20	without	without	ADP
admet-346	73	21	surfactant	surfactant	NOUN
admet-346	73	22	and	and	CCONJ
admet-346	73	23	enzyme	enzyme	NOUN
admet-346	73	24	,	,	PUNCT
admet-346	73	25	biorelevant	biorelevant	ADJ
admet-346	73	26	media	medium	NOUN
admet-346	73	27	)	)	PUNCT
admet-346	73	28	which	which	PRON
admet-346	73	29	will	will	AUX
admet-346	73	30	be	be	AUX
admet-346	73	31	helpful	helpful	ADJ
admet-346	73	32	for	for	ADP
admet-346	73	33	prediction	prediction	NOUN
admet-346	73	34	of	of	ADP
admet-346	73	35	the	the	DET
admet-346	73	36	in	in	ADP
admet-346	73	37	vivo	vivo	ADJ
admet-346	73	38	performance	performance	NOUN
admet-346	73	39	of	of	ADP
admet-346	73	40	cc	cc	PROPN
admet-346	73	41	after	after	ADP
admet-346	73	42	oral	oral	ADJ
admet-346	73	43	administration	administration	NOUN
admet-346	73	44	.	.	PUNCT
admet-346	74	1	experimental	experimental	ADJ
admet-346	74	2	materials	material	NOUN
admet-346	74	3	candesartan	candesartan	VERB
admet-346	74	4	cilexetil	cilexetil	NOUN
admet-346	74	5	and	and	CCONJ
admet-346	74	6	immediate	immediate	ADJ
admet-346	74	7	release	release	NOUN
admet-346	74	8	(	(	PUNCT
admet-346	74	9	ir	ir	NOUN
admet-346	74	10	)	)	PUNCT
admet-346	74	11	tablets	tablet	NOUN
admet-346	74	12	carzap	carzap	NOUN
admet-346	74	13	(	(	PUNCT
admet-346	74	14	product	product	NOUN
admet-346	74	15	of	of	ADP
admet-346	74	16	zentiva	zentiva	PROPN
admet-346	74	17	k.s	k.s	PROPN
admet-346	74	18	.	.	PROPN
admet-346	74	19	,	,	PUNCT
admet-346	74	20	czech	czech	PROPN
admet-346	74	21	republic	republic	NOUN
admet-346	74	22	)	)	PUNCT
admet-346	74	23	with	with	SCONJ
admet-346	74	24	8	8	NUM
admet-346	74	25	mg	mg	NOUN
admet-346	74	26	of	of	ADP
admet-346	74	27	cc	cc	PROPN
admet-346	74	28	were	be	AUX
admet-346	74	29	obtained	obtain	VERB
admet-346	74	30	as	as	ADP
admet-346	74	31	gift	gift	NOUN
admet-346	74	32	samples	sample	NOUN
admet-346	74	33	.	.	PUNCT
admet-346	75	1	all	all	DET
admet-346	75	2	chemicals	chemical	NOUN
admet-346	75	3	used	use	VERB
admet-346	75	4	in	in	ADP
admet-346	75	5	the	the	DET
admet-346	75	6	study	study	NOUN
admet-346	75	7	were	be	AUX
admet-346	75	8	of	of	ADP
admet-346	75	9	analytical	analytical	ADJ
admet-346	75	10	grade	grade	NOUN
admet-346	75	11	.	.	PUNCT
admet-346	76	1	the	the	DET
admet-346	76	2	composition	composition	NOUN
admet-346	76	3	of	of	ADP
admet-346	76	4	the	the	DET
admet-346	76	5	prepared	prepared	ADJ
admet-346	76	6	media	media	NOUN
admet-346	76	7	is	be	AUX
admet-346	76	8	presented	present	VERB
admet-346	76	9	in	in	ADP
admet-346	76	10	table	table	NOUN
admet-346	76	11	1	1	NUM
admet-346	76	12	and	and	CCONJ
admet-346	76	13	table	table	NOUN
admet-346	76	14	2	2	NUM
admet-346	76	15	.	.	PUNCT
admet-346	76	16	table	table	NOUN
admet-346	76	17	1	1	NUM
admet-346	76	18	.	.	PUNCT
admet-346	77	1	composition	composition	NOUN
admet-346	77	2	of	of	ADP
admet-346	77	3	gastric	gastric	ADJ
admet-346	77	4	media	medium	NOUN
admet-346	77	5	.	.	PUNCT
admet-346	78	1	component	component	NOUN
admet-346	78	2	fassgf	fassgf	PROPN
admet-346	78	3	sgf	sgf	PROPN
admet-346	78	4	sgfsp	sgfsp	PROPN
admet-346	78	5	sgfsls	sgfsls	PROPN
admet-346	78	6	sgftriton	sgftriton	PROPN
admet-346	78	7	sodium	sodium	PROPN
admet-346	78	8	taurocholate	taurocholate	NOUN
admet-346	78	9	(	(	PUNCT
admet-346	78	10	mm	mm	NOUN
admet-346	78	11	)	)	PUNCT
admet-346	78	12	0.08	0.08	NUM
admet-346	78	13	lecithin	lecithin	NOUN
admet-346	78	14	(	(	PUNCT
admet-346	78	15	mm	mm	NOUN
admet-346	78	16	)	)	PUNCT
admet-346	78	17	0.02	0.02	NUM
admet-346	78	18	sodium	sodium	NOUN
admet-346	78	19	lauryl	lauryl	NOUN
admet-346	78	20	sulfate	sulfate	NOUN
admet-346	78	21	(	(	PUNCT
admet-346	78	22	%	%	INTJ
admet-346	78	23	,	,	PUNCT
admet-346	78	24	w	w	PROPN
admet-346	78	25	/	/	SYM
admet-346	78	26	v	v	NOUN
admet-346	78	27	)	)	PUNCT
admet-346	78	28	0.25	0.25	NUM
admet-346	78	29	triton	triton	PROPN
admet-346	78	30	x-100	x-100	PROPN
admet-346	79	1	(	(	PUNCT
admet-346	79	2	%	%	INTJ
admet-346	79	3	,	,	PUNCT
admet-346	79	4	w	w	PROPN
admet-346	79	5	/	/	SYM
admet-346	79	6	v	v	NOUN
admet-346	79	7	)	)	PUNCT
admet-346	79	8	0.10	0.10	NUM
admet-346	79	9	pepsin	pepsin	NOUN
admet-346	79	10	(	(	PUNCT
admet-346	79	11	mg	mg	PROPN
admet-346	79	12	/	/	SYM
admet-346	79	13	ml	ml	NOUN
admet-346	79	14	)	)	PUNCT
admet-346	79	15	0.10	0.10	NUM
admet-346	79	16	3.20	3.20	NUM
admet-346	79	17	sodium	sodium	NOUN
admet-346	79	18	chloride	chloride	NOUN
admet-346	79	19	(	(	PUNCT
admet-346	79	20	mm	mm	NOUN
admet-346	79	21	)	)	PUNCT
admet-346	79	22	34.20	34.20	NUM
admet-346	79	23	34.20	34.20	NUM
admet-346	79	24	34.20	34.20	NUM
admet-346	79	25	34.20	34.20	NUM
admet-346	79	26	34.20	34.20	NUM
admet-346	79	27	ph	ph	NOUN
admet-346	79	28	(	(	PUNCT
admet-346	79	29	adjusted	adjust	VERB
admet-346	79	30	by	by	ADP
admet-346	79	31	hydrochloric	hydrochloric	ADJ
admet-346	79	32	acid	acid	NOUN
admet-346	79	33	)	)	PUNCT
admet-346	79	34	1.6	1.6	NUM
admet-346	79	35	1.2	1.2	NUM
admet-346	79	36	1.2	1.2	NUM
admet-346	79	37	1.2	1.2	NUM
admet-346	79	38	1.2	1.2	NUM
admet-346	79	39	table	table	NOUN
admet-346	79	40	2	2	NUM
admet-346	79	41	.	.	PUNCT
admet-346	79	42	composition	composition	NOUN
admet-346	79	43	of	of	ADP
admet-346	79	44	intestinal	intestinal	ADJ
admet-346	79	45	media	medium	NOUN
admet-346	79	46	.	.	PUNCT
admet-346	80	1	component	component	NOUN
admet-346	80	2	fassif	fassif	NOUN
admet-346	80	3	sifsp	sifsp	PROPN
admet-346	80	4	ppt20	ppt20	PROPN
admet-346	80	5	sodium	sodium	NOUN
admet-346	80	6	taurocholate	taurocholate	NOUN
admet-346	80	7	(	(	PUNCT
admet-346	80	8	mm	mm	NOUN
admet-346	80	9	)	)	PUNCT
admet-346	80	10	3.00	3.00	NUM
admet-346	80	11	lecithin	lecithin	NOUN
admet-346	80	12	(	(	PUNCT
admet-346	80	13	mm	mm	NOUN
admet-346	80	14	)	)	PUNCT
admet-346	80	15	0.75	0.75	NUM
admet-346	80	16	tween	tween	NOUN
admet-346	80	17	20	20	NUM
admet-346	80	18	(	(	PUNCT
admet-346	80	19	%	%	INTJ
admet-346	80	20	,	,	PUNCT
admet-346	80	21	w	w	PROPN
admet-346	80	22	/	/	SYM
admet-346	80	23	w	w	NOUN
admet-346	80	24	)	)	PUNCT
admet-346	80	25	0.35	0.35	NUM
admet-346	80	26	pancreatin	pancreatin	ADJ
admet-346	80	27	(	(	PUNCT
admet-346	80	28	mg	mg	PROPN
admet-346	80	29	/	/	SYM
admet-346	80	30	ml	ml	NOUN
admet-346	80	31	)	)	PUNCT
admet-346	80	32	monobasic	monobasic	PROPN
admet-346	80	33	sodium	sodium	NOUN
admet-346	80	34	phosphate	phosphate	NOUN
admet-346	80	35	(	(	PUNCT
admet-346	80	36	mm	mm	NOUN
admet-346	80	37	)	)	PUNCT
admet-346	80	38	28.36	28.36	NUM
admet-346	80	39	monobasic	monobasic	NOUN
admet-346	80	40	potassium	potassium	NOUN
admet-346	80	41	phosphate	phosphate	NOUN
admet-346	80	42	(	(	PUNCT
admet-346	80	43	mm	mm	NOUN
admet-346	80	44	)	)	PUNCT
admet-346	80	45	49.97	49.97	NUM
admet-346	80	46	50.00	50.00	NUM
admet-346	80	47	sodium	sodium	NOUN
admet-346	80	48	hydroxide	hydroxide	NOUN
admet-346	80	49	(	(	PUNCT
admet-346	80	50	mm	mm	NOUN
admet-346	80	51	)	)	PUNCT
admet-346	80	52	8.70	8.70	NUM
admet-346	80	53	45.00	45.00	NUM
admet-346	80	54	sodium	sodium	NOUN
admet-346	80	55	chloride	chloride	NOUN
admet-346	80	56	(	(	PUNCT
admet-346	80	57	mm	mm	NOUN
admet-346	80	58	)	)	PUNCT
admet-346	80	59	105.85	105.85	NUM
admet-346	80	60	ph	ph	NOUN
admet-346	80	61	(	(	PUNCT
admet-346	80	62	adjusted	adjust	VERB
admet-346	80	63	by	by	ADP
admet-346	80	64	sodium	sodium	NOUN
admet-346	80	65	hydroxide	hydroxide	NOUN
admet-346	80	66	)	)	PUNCT
admet-346	80	67	6.5	6.5	NUM
admet-346	80	68	6.8	6.8	NUM
admet-346	80	69	6.5	6.5	NUM
admet-346	80	70	gruberová	gruberová	NOUN
admet-346	80	71	and	and	CCONJ
admet-346	80	72	kratochvil	kratochvil	PROPN
admet-346	80	73	admet	admet	PROPN
admet-346	80	74	&	&	CCONJ
admet-346	80	75	dmpk	dmpk	PROPN
admet-346	80	76	5(1	5(1	NUM
admet-346	80	77	)	)	PUNCT
admet-346	80	78	(	(	PUNCT
admet-346	80	79	2017	2017	NUM
admet-346	80	80	)	)	PUNCT
admet-346	80	81	39	39	NUM
admet-346	80	82	-	-	SYM
admet-346	80	83	46	46	NUM
admet-346	80	84	42	42	NUM
admet-346	80	85	methods	method	NOUN
admet-346	80	86	solubility	solubility	NOUN
admet-346	80	87	studies	study	VERB
admet-346	80	88	the	the	DET
admet-346	80	89	solubility	solubility	NOUN
admet-346	80	90	of	of	ADP
admet-346	80	91	cc	cc	PROPN
admet-346	80	92	was	be	AUX
admet-346	80	93	determined	determine	VERB
admet-346	80	94	by	by	ADP
admet-346	80	95	the	the	DET
admet-346	80	96	shake	shake	NOUN
admet-346	80	97	-	-	PUNCT
admet-346	80	98	flask	flask	NOUN
admet-346	80	99	method	method	NOUN
admet-346	80	100	.	.	PUNCT
admet-346	81	1	cc	cc	PROPN
admet-346	81	2	was	be	AUX
admet-346	81	3	added	add	VERB
admet-346	81	4	in	in	ADP
admet-346	81	5	excess	excess	NOUN
admet-346	81	6	into	into	ADP
admet-346	81	7	specific	specific	ADJ
admet-346	81	8	solvent	solvent	NOUN
admet-346	81	9	and	and	CCONJ
admet-346	81	10	shaken	shake	VERB
admet-346	81	11	for	for	ADP
admet-346	81	12	24	24	NUM
admet-346	81	13	hours	hour	NOUN
admet-346	81	14	at	at	ADP
admet-346	81	15	37	37	NUM
admet-346	81	16	°	°	SYM
admet-346	81	17	c	c	NOUN
admet-346	81	18	in	in	ADP
admet-346	81	19	a	a	DET
admet-346	81	20	thermostated	thermostated	ADJ
admet-346	81	21	orbital	orbital	ADJ
admet-346	81	22	platform	platform	NOUN
admet-346	81	23	shaker	shaker	NOUN
admet-346	81	24	(	(	PUNCT
admet-346	81	25	heidoplh	heidoplh	NOUN
admet-346	81	26	,	,	PUNCT
admet-346	81	27	unimax	unimax	PROPN
admet-346	81	28	1010	1010	NUM
admet-346	81	29	with	with	ADP
admet-346	81	30	incubator	incubator	NOUN
admet-346	81	31	1000	1000	NUM
admet-346	81	32	)	)	PUNCT
admet-346	81	33	to	to	PART
admet-346	81	34	obtain	obtain	VERB
admet-346	81	35	equilibrium	equilibrium	NOUN
admet-346	81	36	solubility	solubility	NOUN
admet-346	81	37	[	[	X
admet-346	81	38	18	18	NUM
admet-346	81	39	,	,	PUNCT
admet-346	81	40	19	19	NUM
admet-346	81	41	]	]	PUNCT
admet-346	81	42	.	.	PUNCT
admet-346	82	1	due	due	ADP
admet-346	82	2	to	to	ADP
admet-346	82	3	the	the	DET
admet-346	82	4	low	low	ADJ
admet-346	82	5	stability	stability	NOUN
admet-346	82	6	of	of	ADP
admet-346	82	7	cc	cc	PROPN
admet-346	82	8	,	,	PUNCT
admet-346	82	9	a	a	DET
admet-346	82	10	‘	'	PUNCT
admet-346	82	11	shortened	shorten	VERB
admet-346	82	12	shake	shake	NOUN
admet-346	82	13	flask	flask	NOUN
admet-346	82	14	method	method	NOUN
admet-346	82	15	’	'	PUNCT
admet-346	82	16	was	be	AUX
admet-346	82	17	suggest	suggest	VERB
admet-346	82	18	,	,	PUNCT
admet-346	82	19	the	the	DET
admet-346	82	20	shaken	shake	VERB
admet-346	82	21	time	time	NOUN
admet-346	82	22	of	of	ADP
admet-346	82	23	certain	certain	ADJ
admet-346	82	24	saturated	saturate	VERB
admet-346	82	25	solutions	solution	NOUN
admet-346	82	26	,	,	PUNCT
admet-346	82	27	namely	namely	ADV
admet-346	82	28	with	with	ADP
admet-346	82	29	solvents	solvent	NOUN
admet-346	82	30	sgf	sgf	PROPN
admet-346	82	31	,	,	PUNCT
admet-346	82	32	fassgf	fassgf	NOUN
admet-346	82	33	and	and	CCONJ
admet-346	82	34	sgftriton	sgftriton	PROPN
admet-346	82	35	,	,	PUNCT
admet-346	82	36	was	be	AUX
admet-346	82	37	only	only	ADV
admet-346	82	38	2	2	NUM
admet-346	82	39	hours	hour	NOUN
admet-346	82	40	or	or	CCONJ
admet-346	82	41	12	12	NUM
admet-346	82	42	hours	hour	NOUN
admet-346	82	43	.	.	PUNCT
admet-346	83	1	the	the	DET
admet-346	83	2	concentration	concentration	NOUN
admet-346	83	3	of	of	ADP
admet-346	83	4	cc	cc	PROPN
admet-346	83	5	was	be	AUX
admet-346	83	6	measured	measure	VERB
admet-346	83	7	by	by	ADP
admet-346	83	8	a	a	DET
admet-346	83	9	uv	uv	NOUN
admet-346	83	10	-	-	PUNCT
admet-346	83	11	vis	vis	X
admet-346	83	12	spectrophotometer	spectrophotometer	X
admet-346	83	13	(	(	PUNCT
admet-346	83	14	schimadzu	schimadzu	NOUN
admet-346	83	15	uv	uv	PROPN
admet-346	83	16	mini	mini	NOUN
admet-346	83	17	1240	1240	NUM
admet-346	83	18	)	)	PUNCT
admet-346	83	19	at	at	ADP
admet-346	83	20	256	256	NUM
admet-346	83	21	nm	nm	NOUN
admet-346	83	22	and	and	CCONJ
admet-346	83	23	before	before	SCONJ
admet-346	83	24	the	the	DET
admet-346	83	25	analysis	analysis	NOUN
admet-346	83	26	supernatant	supernatant	NOUN
admet-346	83	27	had	have	AUX
admet-346	83	28	been	be	AUX
admet-346	83	29	filtered	filter	VERB
admet-346	83	30	through	through	ADP
admet-346	83	31	a	a	DET
admet-346	83	32	35	35	NUM
admet-346	83	33	micron	micron	NOUN
admet-346	83	34	porous	porous	ADJ
admet-346	83	35	filter	filter	NOUN
admet-346	83	36	from	from	ADP
admet-346	83	37	uhmw	uhmw	PROPN
admet-346	83	38	polyethylene	polyethylene	NOUN
admet-346	83	39	.	.	PUNCT
admet-346	84	1	all	all	DET
admet-346	84	2	tests	test	NOUN
admet-346	84	3	were	be	AUX
admet-346	84	4	carried	carry	VERB
admet-346	84	5	out	out	ADP
admet-346	84	6	in	in	ADP
admet-346	84	7	triplicate	triplicate	NOUN
admet-346	84	8	.	.	PUNCT
admet-346	85	1	concentration	concentration	NOUN
admet-346	85	2	of	of	ADP
admet-346	85	3	dissolved	dissolved	ADJ
admet-346	85	4	cc	cc	NOUN
admet-346	85	5	was	be	AUX
admet-346	85	6	determined	determine	VERB
admet-346	85	7	from	from	ADP
admet-346	85	8	calibration	calibration	NOUN
admet-346	85	9	curve	curve	NOUN
admet-346	85	10	.	.	PUNCT
admet-346	86	1	the	the	DET
admet-346	86	2	stock	stock	NOUN
admet-346	86	3	solution	solution	NOUN
admet-346	86	4	of	of	ADP
admet-346	86	5	cc	cc	PROPN
admet-346	86	6	was	be	AUX
admet-346	86	7	prepared	prepare	VERB
admet-346	86	8	in	in	ADP
admet-346	86	9	the	the	DET
admet-346	86	10	suitable	suitable	ADJ
admet-346	86	11	quantity	quantity	NOUN
admet-346	86	12	of	of	ADP
admet-346	86	13	methanol	methanol	NOUN
admet-346	86	14	.	.	PUNCT
admet-346	87	1	the	the	DET
admet-346	87	2	aliquot	aliquot	NOUN
admet-346	87	3	of	of	ADP
admet-346	87	4	this	this	DET
admet-346	87	5	solution	solution	NOUN
admet-346	87	6	was	be	AUX
admet-346	87	7	diluted	dilute	VERB
admet-346	87	8	with	with	ADP
admet-346	87	9	the	the	DET
admet-346	87	10	specific	specific	ADJ
admet-346	87	11	solvent	solvent	NOUN
admet-346	87	12	to	to	PART
admet-346	87	13	get	get	VERB
admet-346	87	14	the	the	DET
admet-346	87	15	final	final	ADJ
admet-346	87	16	concentration	concentration	NOUN
admet-346	87	17	of	of	ADP
admet-346	87	18	standard	standard	ADJ
admet-346	87	19	solutions	solution	NOUN
admet-346	87	20	(	(	PUNCT
admet-346	87	21	10	10	NUM
admet-346	87	22	-	-	SYM
admet-346	87	23	30	30	NUM
admet-346	87	24	µg	µg	NOUN
admet-346	87	25	/	/	SYM
admet-346	87	26	ml	ml	NOUN
admet-346	87	27	)	)	PUNCT
admet-346	87	28	.	.	PUNCT
admet-346	88	1	the	the	DET
admet-346	88	2	method	method	NOUN
admet-346	88	3	obeyed	obey	VERB
admet-346	88	4	lambert	lambert	PROPN
admet-346	88	5	-beer	-beer	PROPN
admet-346	88	6	law	law	NOUN
admet-346	88	7	(	(	PUNCT
admet-346	88	8	r	r	NOUN
admet-346	88	9	2	2	NUM
admet-346	88	10	>	>	NOUN
admet-346	88	11	0.99	0.99	NUM
admet-346	88	12	)	)	PUNCT
admet-346	88	13	.	.	PUNCT
admet-346	89	1	dissolution	dissolution	PROPN
admet-346	89	2	studies	study	NOUN
admet-346	89	3	dissolution	dissolution	NOUN
admet-346	89	4	tests	test	NOUN
admet-346	89	5	were	be	AUX
admet-346	89	6	performed	perform	VERB
admet-346	89	7	in	in	ADP
admet-346	89	8	a	a	DET
admet-346	89	9	paddle	paddle	NOUN
admet-346	89	10	apparatus	apparatus	NOUN
admet-346	89	11	(	(	PUNCT
admet-346	89	12	usp	usp	NOUN
admet-346	89	13	ii	ii	PROPN
admet-346	89	14	)	)	PUNCT
admet-346	89	15	.	.	PUNCT
admet-346	90	1	the	the	DET
admet-346	90	2	stirring	stir	VERB
admet-346	90	3	rate	rate	NOUN
admet-346	90	4	was	be	AUX
admet-346	90	5	50	50	NUM
admet-346	90	6	rpm	rpm	NOUN
admet-346	90	7	.	.	PUNCT
admet-346	91	1	the	the	DET
admet-346	91	2	dissolution	dissolution	PROPN
admet-346	91	3	medium	medium	NOUN
admet-346	91	4	was	be	AUX
admet-346	91	5	filtered	filter	VERB
admet-346	91	6	through	through	ADP
admet-346	91	7	a	a	DET
admet-346	91	8	35	35	NUM
admet-346	91	9	micron	micron	NOUN
admet-346	91	10	porous	porous	ADJ
admet-346	91	11	filter	filter	NOUN
admet-346	91	12	from	from	ADP
admet-346	91	13	uhmw	uhmw	PROPN
admet-346	91	14	polyethylene	polyethylene	NOUN
admet-346	91	15	,	,	PUNCT
admet-346	91	16	pumped	pump	VERB
admet-346	91	17	through	through	ADP
admet-346	91	18	a	a	DET
admet-346	91	19	10	10	NUM
admet-346	91	20	mm	mm	NOUN
admet-346	91	21	flow	flow	NOUN
admet-346	91	22	cell	cell	NOUN
admet-346	91	23	by	by	ADP
admet-346	91	24	a	a	DET
admet-346	91	25	peristaltic	peristaltic	ADJ
admet-346	91	26	pump	pump	NOUN
admet-346	91	27	(	(	PUNCT
admet-346	91	28	ismatic	ismatic	ADJ
admet-346	91	29	,	,	PUNCT
admet-346	91	30	reglo	reglo	PROPN
admet-346	91	31	digital	digital	ADJ
admet-346	91	32	ms-2/6	ms-2/6	NOUN
admet-346	91	33	)	)	PUNCT
admet-346	91	34	and	and	CCONJ
admet-346	91	35	analyzed	analyze	VERB
admet-346	91	36	by	by	ADP
admet-346	91	37	a	a	DET
admet-346	91	38	uv	uv	NOUN
admet-346	91	39	-	-	PUNCT
admet-346	91	40	vis	vis	X
admet-346	91	41	spectrophotometer	spectrophotometer	X
admet-346	91	42	(	(	PUNCT
admet-346	91	43	schimadzu	schimadzu	NOUN
admet-346	91	44	uv	uv	PROPN
admet-346	91	45	mini	mini	NOUN
admet-346	91	46	1240	1240	NUM
admet-346	91	47	)	)	PUNCT
admet-346	91	48	,	,	PUNCT
admet-346	91	49	wavelenght	wavelenght	NOUN
admet-346	91	50	was	be	AUX
admet-346	91	51	256	256	NUM
admet-346	91	52	nm	nm	NOUN
admet-346	91	53	.	.	PUNCT
admet-346	92	1	all	all	DET
admet-346	92	2	dissolution	dissolution	ADJ
admet-346	92	3	tests	test	NOUN
admet-346	92	4	were	be	AUX
admet-346	92	5	conducted	conduct	VERB
admet-346	92	6	in	in	ADP
admet-346	92	7	triplicate	triplicate	NOUN
admet-346	92	8	.	.	PUNCT
admet-346	93	1	the	the	DET
admet-346	93	2	tablets	tablet	NOUN
admet-346	93	3	of	of	ADP
admet-346	93	4	cc	cc	NOUN
admet-346	93	5	were	be	AUX
admet-346	93	6	placed	place	VERB
admet-346	93	7	in	in	ADP
admet-346	93	8	500	500	NUM
admet-346	93	9	ml	ml	NOUN
admet-346	93	10	of	of	ADP
admet-346	93	11	dissolution	dissolution	NOUN
admet-346	93	12	medium	medium	NOUN
admet-346	93	13	(	(	PUNCT
admet-346	93	14	37±0.5	37±0.5	NUM
admet-346	93	15	°	°	NOUN
admet-346	93	16	c	c	NOUN
admet-346	93	17	)	)	PUNCT
admet-346	93	18	.	.	PUNCT
admet-346	94	1	the	the	DET
admet-346	94	2	volume	volume	NOUN
admet-346	94	3	was	be	AUX
admet-346	94	4	set	set	VERB
admet-346	94	5	as	as	ADP
admet-346	94	6	the	the	DET
admet-346	94	7	smallest	small	ADJ
admet-346	94	8	amount	amount	NOUN
admet-346	94	9	which	which	PRON
admet-346	94	10	enables	enable	VERB
admet-346	94	11	the	the	DET
admet-346	94	12	performance	performance	NOUN
admet-346	94	13	of	of	ADP
admet-346	94	14	the	the	DET
admet-346	94	15	dissolution	dissolution	NOUN
admet-346	94	16	testing	testing	NOUN
admet-346	94	17	in	in	ADP
admet-346	94	18	usp	usp	PROPN
admet-346	94	19	ii	ii	NOUN
admet-346	95	1	[	[	X
admet-346	95	2	2	2	NUM
admet-346	95	3	]	]	PUNCT
admet-346	95	4	.	.	PUNCT
admet-346	96	1	to	to	PART
admet-346	96	2	simulate	simulate	VERB
admet-346	96	3	the	the	DET
admet-346	96	4	fasted	fasted	ADJ
admet-346	96	5	state	state	NOUN
admet-346	96	6	,	,	PUNCT
admet-346	96	7	the	the	DET
admet-346	96	8	volume	volume	NOUN
admet-346	96	9	of	of	ADP
admet-346	96	10	media	medium	NOUN
admet-346	96	11	in	in	ADP
admet-346	96	12	the	the	DET
admet-346	96	13	range	range	NOUN
admet-346	96	14	of	of	ADP
admet-346	96	15	250	250	NUM
admet-346	96	16	-	-	SYM
admet-346	96	17	300	300	NUM
admet-346	96	18	ml	ml	NOUN
admet-346	96	19	(	(	PUNCT
admet-346	96	20	stomach	stomach	NOUN
admet-346	96	21	)	)	PUNCT
admet-346	96	22	or	or	CCONJ
admet-346	96	23	300	300	NUM
admet-346	96	24	-	-	SYM
admet-346	96	25	500	500	NUM
admet-346	96	26	ml	ml	NOUN
admet-346	96	27	(	(	PUNCT
admet-346	96	28	duodenum	duodenum	NOUN
admet-346	96	29	)	)	PUNCT
admet-346	96	30	is	be	AUX
admet-346	96	31	recommended	recommend	VERB
admet-346	96	32	[	[	PUNCT
admet-346	96	33	8	8	NUM
admet-346	96	34	]	]	PUNCT
admet-346	96	35	,	,	PUNCT
admet-346	96	36	but	but	CCONJ
admet-346	96	37	the	the	DET
admet-346	96	38	volume	volume	NOUN
admet-346	96	39	reduction	reduction	NOUN
admet-346	96	40	was	be	AUX
admet-346	96	41	not	not	PART
admet-346	96	42	feasible	feasible	ADJ
admet-346	96	43	.	.	PUNCT
admet-346	97	1	despite	despite	SCONJ
admet-346	97	2	the	the	DET
admet-346	97	3	volume	volume	NOUN
admet-346	97	4	reduction	reduction	NOUN
admet-346	97	5	,	,	PUNCT
admet-346	97	6	sink	sink	NOUN
admet-346	97	7	conditions	condition	NOUN
admet-346	97	8	were	be	AUX
admet-346	97	9	maintained	maintain	VERB
admet-346	97	10	in	in	ADP
admet-346	97	11	medium	medium	ADJ
admet-346	97	12	ppt20	ppt20	NOUN
admet-346	97	13	regarding	regard	VERB
admet-346	97	14	on	on	ADP
admet-346	97	15	our	our	PRON
admet-346	97	16	solubility	solubility	NOUN
admet-346	97	17	data	datum	NOUN
admet-346	97	18	of	of	ADP
admet-346	97	19	cc	cc	PROPN
admet-346	97	20	.	.	PUNCT
admet-346	98	1	these	these	DET
admet-346	98	2	data	datum	NOUN
admet-346	98	3	verify	verify	VERB
admet-346	98	4	findings	finding	NOUN
admet-346	98	5	reported	report	VERB
admet-346	98	6	by	by	ADP
admet-346	98	7	hoppe	hoppe	PROPN
admet-346	98	8	and	and	CCONJ
admet-346	98	9	sznitowska	sznitowska	PROPN
admet-346	98	10	[	[	X
admet-346	98	11	18	18	NUM
admet-346	98	12	]	]	PUNCT
admet-346	98	13	.	.	PUNCT
admet-346	99	1	results	result	NOUN
admet-346	99	2	and	and	CCONJ
admet-346	99	3	discussion	discussion	NOUN
admet-346	99	4	solubility	solubility	NOUN
admet-346	99	5	study	study	VERB
admet-346	99	6	the	the	DET
admet-346	99	7	equilibrium	equilibrium	NOUN
admet-346	99	8	solubility	solubility	NOUN
admet-346	99	9	data	datum	NOUN
admet-346	99	10	(	(	PUNCT
admet-346	99	11	table	table	NOUN
admet-346	99	12	3	3	NUM
admet-346	99	13	)	)	PUNCT
admet-346	99	14	confirm	confirm	VERB
admet-346	99	15	that	that	SCONJ
admet-346	99	16	cc	cc	PROPN
admet-346	99	17	is	be	AUX
admet-346	99	18	a	a	DET
admet-346	99	19	poorly	poorly	ADV
admet-346	99	20	soluble	soluble	ADJ
admet-346	99	21	and	and	CCONJ
admet-346	99	22	stable	stable	ADJ
admet-346	99	23	compound	compound	NOUN
admet-346	99	24	.	.	PUNCT
admet-346	100	1	the	the	DET
admet-346	100	2	values	value	NOUN
admet-346	100	3	of	of	ADP
admet-346	100	4	cc	cc	NOUN
admet-346	100	5	solubility	solubility	NOUN
admet-346	100	6	in	in	ADP
admet-346	100	7	sgf	sgf	PROPN
admet-346	100	8	after	after	ADP
admet-346	100	9	24	24	NUM
admet-346	100	10	hours	hour	NOUN
admet-346	100	11	of	of	ADP
admet-346	100	12	shaking	shaking	NOUN
admet-346	100	13	were	be	AUX
admet-346	100	14	so	so	ADV
admet-346	100	15	small	small	ADJ
admet-346	100	16	that	that	SCONJ
admet-346	100	17	it	it	PRON
admet-346	100	18	was	be	AUX
admet-346	100	19	not	not	PART
admet-346	100	20	possible	possible	ADJ
admet-346	100	21	to	to	PART
admet-346	100	22	record	record	VERB
admet-346	100	23	them	they	PRON
admet-346	100	24	by	by	ADP
admet-346	100	25	the	the	DET
admet-346	100	26	uv	uv	NOUN
admet-346	100	27	-	-	PUNCT
admet-346	100	28	vis	vis	X
admet-346	100	29	spectrophotometer	spectrophotometer	NOUN
admet-346	100	30	.	.	PUNCT
admet-346	101	1	zero	zero	NUM
admet-346	101	2	solubility	solubility	NOUN
admet-346	101	3	in	in	ADP
admet-346	101	4	sgf	sgf	PROPN
admet-346	101	5	and	and	CCONJ
admet-346	101	6	very	very	ADV
admet-346	101	7	low	low	ADJ
admet-346	101	8	solubility	solubility	NOUN
admet-346	101	9	in	in	ADP
admet-346	101	10	fassgf	fassgf	NOUN
admet-346	101	11	(	(	PUNCT
admet-346	101	12	0.72±0.19	0.72±0.19	NOUN
admet-346	101	13	µg	µg	VERB
admet-346	101	14	/	/	SYM
admet-346	101	15	ml	ml	NOUN
admet-346	101	16	)	)	PUNCT
admet-346	101	17	were	be	AUX
admet-346	101	18	caused	cause	VERB
admet-346	101	19	by	by	ADP
admet-346	101	20	the	the	DET
admet-346	101	21	rapid	rapid	ADJ
admet-346	101	22	cc	cc	NOUN
admet-346	101	23	degradation	degradation	NOUN
admet-346	101	24	at	at	ADP
admet-346	101	25	the	the	DET
admet-346	101	26	acid	acid	PROPN
admet-346	101	27	environment	environment	NOUN
admet-346	101	28	.	.	PUNCT
admet-346	102	1	due	due	ADP
admet-346	102	2	to	to	ADP
admet-346	102	3	the	the	DET
admet-346	102	4	long	long	ADJ
admet-346	102	5	measurement	measurement	NOUN
admet-346	102	6	time	time	NOUN
admet-346	102	7	,	,	PUNCT
admet-346	102	8	the	the	DET
admet-346	102	9	large	large	ADJ
admet-346	102	10	amount	amount	NOUN
admet-346	102	11	of	of	ADP
admet-346	102	12	cc	cc	NOUN
admet-346	102	13	degraded	degrade	VERB
admet-346	102	14	.	.	PUNCT
admet-346	103	1	because	because	SCONJ
admet-346	103	2	of	of	ADP
admet-346	103	3	the	the	DET
admet-346	103	4	cc	cc	NOUN
admet-346	103	5	degradation	degradation	NOUN
admet-346	103	6	,	,	PUNCT
admet-346	103	7	the	the	DET
admet-346	103	8	shaking	shake	VERB
admet-346	103	9	time	time	NOUN
admet-346	103	10	was	be	AUX
admet-346	103	11	shortened	shorten	VERB
admet-346	103	12	to	to	ADP
admet-346	103	13	two	two	NUM
admet-346	103	14	hours	hour	NOUN
admet-346	103	15	for	for	ADP
admet-346	103	16	media	medium	NOUN
admet-346	103	17	sgf	sgf	PROPN
admet-346	103	18	,	,	PUNCT
admet-346	103	19	fassgf	fassgf	NOUN
admet-346	103	20	and	and	CCONJ
admet-346	103	21	sgftriton	sgftriton	PROPN
admet-346	103	22	.	.	PUNCT
admet-346	104	1	from	from	ADP
admet-346	104	2	the	the	DET
admet-346	104	3	obtained	obtain	VERB
admet-346	104	4	data	datum	NOUN
admet-346	104	5	,	,	PUNCT
admet-346	104	6	we	we	PRON
admet-346	104	7	concluded	conclude	VERB
admet-346	104	8	that	that	SCONJ
admet-346	104	9	the	the	DET
admet-346	104	10	shorter	short	ADJ
admet-346	104	11	shaking	shake	VERB
admet-346	104	12	time	time	NOUN
admet-346	104	13	reduced	reduce	VERB
admet-346	104	14	the	the	DET
admet-346	104	15	amount	amount	NOUN
admet-346	104	16	of	of	ADP
admet-346	104	17	emerging	emerge	VERB
admet-346	104	18	degradation	degradation	NOUN
admet-346	104	19	products	product	NOUN
admet-346	104	20	(	(	PUNCT
admet-346	104	21	cc	cc	NOUN
admet-346	104	22	saturation	saturation	NOUN
admet-346	104	23	solubility	solubility	NOUN
admet-346	104	24	was	be	AUX
admet-346	104	25	2.76	2.76	NUM
admet-346	104	26	µg	µg	NOUN
admet-346	104	27	/	/	SYM
admet-346	104	28	ml	ml	NOUN
admet-346	104	29	in	in	ADP
admet-346	104	30	sgf	sgf	PROPN
admet-346	104	31	and	and	CCONJ
admet-346	104	32	0.90	0.90	NUM
admet-346	104	33	µg	µg	ADV
admet-346	104	34	/	/	SYM
admet-346	104	35	ml	ml	NOUN
admet-346	104	36	in	in	ADP
admet-346	104	37	fassgf	fassgf	NOUN
admet-346	104	38	)	)	PUNCT
admet-346	104	39	.	.	PUNCT
admet-346	105	1	but	but	CCONJ
admet-346	105	2	the	the	DET
admet-346	105	3	equilibrium	equilibrium	NOUN
admet-346	105	4	may	may	AUX
admet-346	105	5	not	not	PART
admet-346	105	6	be	be	AUX
admet-346	105	7	always	always	ADV
admet-346	105	8	reached	reach	VERB
admet-346	105	9	in	in	ADP
admet-346	105	10	such	such	ADJ
admet-346	105	11	short	short	ADJ
admet-346	105	12	time	time	NOUN
admet-346	105	13	,	,	PUNCT
admet-346	105	14	as	as	SCONJ
admet-346	105	15	evidenced	evidence	VERB
admet-346	105	16	by	by	ADP
admet-346	105	17	almost	almost	ADV
admet-346	105	18	ten	ten	NUM
admet-346	105	19	times	time	NOUN
admet-346	105	20	lower	low	ADJ
admet-346	105	21	value	value	NOUN
admet-346	105	22	of	of	ADP
admet-346	105	23	cc	cc	NOUN
admet-346	105	24	solubility	solubility	NOUN
admet-346	105	25	in	in	ADP
admet-346	105	26	sgftriton	sgftriton	PROPN
admet-346	105	27	(	(	PUNCT
admet-346	105	28	0.69	0.69	NUM
admet-346	105	29	µg	µg	NOUN
admet-346	105	30	/	/	SYM
admet-346	105	31	ml	ml	NOUN
admet-346	105	32	after	after	ADP
admet-346	105	33	2	2	NUM
admet-346	105	34	hours	hour	NOUN
admet-346	105	35	compared	compare	VERB
admet-346	105	36	to	to	ADP
admet-346	105	37	6.00	6.00	NUM
admet-346	105	38	µg	µg	NOUN
admet-346	105	39	/	/	SYM
admet-346	105	40	ml	ml	NOUN
admet-346	105	41	after	after	ADP
admet-346	105	42	24	24	NUM
admet-346	105	43	hours	hour	NOUN
admet-346	105	44	test	test	NOUN
admet-346	105	45	)	)	PUNCT
admet-346	105	46	.	.	PUNCT
admet-346	106	1	cc	cc	PROPN
admet-346	106	2	gained	gain	VERB
admet-346	106	3	the	the	DET
admet-346	106	4	greatest	great	ADJ
admet-346	106	5	solubility	solubility	NOUN
admet-346	106	6	in	in	ADP
admet-346	106	7	fassgf	fassgf	NOUN
admet-346	106	8	after	after	ADP
admet-346	106	9	12	12	NUM
admet-346	106	10	-	-	PUNCT
admet-346	106	11	hour	hour	NOUN
admet-346	106	12	period	period	NOUN
admet-346	106	13	of	of	ADP
admet-346	106	14	shaking	shake	VERB
admet-346	106	15	(	(	PUNCT
admet-346	106	16	1.59	1.59	NUM
admet-346	106	17	µg	µg	NOUN
admet-346	106	18	/	/	SYM
admet-346	106	19	ml	ml	NOUN
admet-346	106	20	)	)	PUNCT
admet-346	106	21	.	.	PUNCT
admet-346	107	1	for	for	ADP
admet-346	107	2	these	these	DET
admet-346	107	3	data	datum	NOUN
admet-346	107	4	,	,	PUNCT
admet-346	107	5	it	it	PRON
admet-346	107	6	can	can	AUX
admet-346	107	7	be	be	AUX
admet-346	107	8	concluded	conclude	VERB
admet-346	107	9	that	that	SCONJ
admet-346	107	10	12	12	NUM
admet-346	107	11	hours	hour	NOUN
admet-346	107	12	is	be	AUX
admet-346	107	13	an	an	DET
admet-346	107	14	optimal	optimal	ADJ
admet-346	107	15	period	period	NOUN
admet-346	107	16	for	for	ADP
admet-346	107	17	the	the	DET
admet-346	107	18	shake	shake	NOUN
admet-346	107	19	-	-	PUNCT
admet-346	107	20	flask	flask	NOUN
admet-346	107	21	method	method	NOUN
admet-346	107	22	considering	consider	VERB
admet-346	107	23	the	the	DET
admet-346	107	24	solubility	solubility	NOUN
admet-346	107	25	and	and	CCONJ
admet-346	107	26	degradation	degradation	NOUN
admet-346	107	27	of	of	ADP
admet-346	107	28	cc	cc	PROPN
admet-346	107	29	in	in	ADP
admet-346	107	30	fassgf	fassgf	NOUN
admet-346	107	31	.	.	PUNCT
admet-346	108	1	very	very	ADV
admet-346	108	2	low	low	ADJ
admet-346	108	3	amounts	amount	NOUN
admet-346	108	4	of	of	ADP
admet-346	108	5	cc	cc	NOUN
admet-346	108	6	were	be	AUX
admet-346	108	7	dissolved	dissolve	VERB
admet-346	108	8	in	in	ADP
admet-346	108	9	sgfsp	sgfsp	NOUN
admet-346	108	10	and	and	CCONJ
admet-346	108	11	sifsp	sifsp	NOUN
admet-346	108	12	,	,	PUNCT
admet-346	108	13	1.35	1.35	NUM
admet-346	108	14	and	and	CCONJ
admet-346	108	15	0.65	0.65	NUM
admet-346	108	16	µg	µg	NOUN
admet-346	108	17	/	/	SYM
admet-346	108	18	ml	ml	NOUN
admet-346	108	19	,	,	PUNCT
admet-346	108	20	respectively	respectively	ADV
admet-346	108	21	.	.	PUNCT
admet-346	109	1	in	in	ADP
admet-346	109	2	this	this	DET
admet-346	109	3	case	case	NOUN
admet-346	109	4	,	,	PUNCT
admet-346	109	5	the	the	DET
admet-346	109	6	low	low	ADJ
admet-346	109	7	solubility	solubility	NOUN
admet-346	109	8	of	of	ADP
admet-346	109	9	cc	cc	NOUN
admet-346	109	10	was	be	AUX
admet-346	109	11	probably	probably	ADV
admet-346	109	12	the	the	DET
admet-346	109	13	main	main	ADJ
admet-346	109	14	reason	reason	NOUN
admet-346	109	15	of	of	ADP
admet-346	109	16	such	such	ADJ
admet-346	109	17	results	result	NOUN
admet-346	109	18	.	.	PUNCT
admet-346	110	1	we	we	PRON
admet-346	110	2	observed	observe	VERB
admet-346	110	3	that	that	SCONJ
admet-346	110	4	the	the	DET
admet-346	110	5	powder	powder	NOUN
admet-346	110	6	of	of	ADP
admet-346	110	7	cc	cc	PROPN
admet-346	110	8	admet	admet	PROPN
admet-346	110	9	&	&	CCONJ
admet-346	110	10	dmpk	dmpk	PROPN
admet-346	110	11	5(1	5(1	NUM
admet-346	110	12	)	)	PUNCT
admet-346	110	13	(	(	PUNCT
admet-346	110	14	2017	2017	NUM
admet-346	110	15	)	)	PUNCT
admet-346	110	16	39	39	NUM
admet-346	110	17	-	-	SYM
admet-346	110	18	46	46	NUM
admet-346	110	19	biorelevant	biorelevant	NOUN
admet-346	110	20	dissolution	dissolution	NOUN
admet-346	110	21	of	of	ADP
admet-346	110	22	candesartan	candesartan	PROPN
admet-346	110	23	cilexetil	cilexetil	PROPN
admet-346	110	24	doi	doi	PROPN
admet-346	110	25	:	:	PUNCT
admet-346	110	26	10.5599	10.5599	NUM
admet-346	110	27	/	/	SYM
admet-346	110	28	admet.5.1.346	admet.5.1.346	NUM
admet-346	110	29	43	43	NUM
admet-346	110	30	was	be	AUX
admet-346	110	31	almost	almost	ADV
admet-346	110	32	dry	dry	ADJ
admet-346	110	33	after	after	ADP
admet-346	110	34	the	the	DET
admet-346	110	35	tests	test	NOUN
admet-346	110	36	because	because	SCONJ
admet-346	110	37	in	in	ADP
admet-346	110	38	the	the	DET
admet-346	110	39	media	medium	NOUN
admet-346	110	40	without	without	ADP
admet-346	110	41	enzymes	enzyme	NOUN
admet-346	110	42	and	and	CCONJ
admet-346	110	43	surfactants	surfactant	NOUN
admet-346	110	44	the	the	DET
admet-346	110	45	required	required	ADJ
admet-346	110	46	wetting	wetting	NOUN
admet-346	110	47	of	of	ADP
admet-346	110	48	the	the	DET
admet-346	110	49	samples	sample	NOUN
admet-346	110	50	was	be	AUX
admet-346	110	51	not	not	PART
admet-346	110	52	reached	reach	VERB
admet-346	110	53	.	.	PUNCT
admet-346	111	1	satturwar	satturwar	AUX
admet-346	111	2	et	et	PROPN
admet-346	111	3	al	al	PROPN
admet-346	111	4	.	.	PROPN
admet-346	111	5	published	publish	VERB
admet-346	111	6	the	the	DET
admet-346	111	7	values	value	NOUN
admet-346	111	8	of	of	ADP
admet-346	111	9	cc	cc	NOUN
admet-346	111	10	solubility	solubility	NOUN
admet-346	111	11	in	in	ADP
admet-346	111	12	sgf	sgf	PROPN
admet-346	111	13	(	(	PUNCT
admet-346	111	14	0.6	0.6	NUM
admet-346	111	15	µg	µg	NOUN
admet-346	111	16	/	/	SYM
admet-346	111	17	ml	ml	NOUN
admet-346	111	18	)	)	PUNCT
admet-346	111	19	and	and	CCONJ
admet-346	111	20	sif	sif	X
admet-346	111	21	(	(	PUNCT
admet-346	111	22	8.6	8.6	NUM
admet-346	111	23	µg	µg	NOUN
admet-346	111	24	/	/	SYM
admet-346	111	25	ml	ml	NOUN
admet-346	111	26	)	)	PUNCT
admet-346	112	1	[	[	X
admet-346	112	2	20	20	NUM
admet-346	112	3	]	]	PUNCT
admet-346	112	4	.	.	PUNCT
admet-346	113	1	however	however	ADV
admet-346	113	2	,	,	PUNCT
admet-346	113	3	the	the	DET
admet-346	113	4	preparations	preparation	NOUN
admet-346	113	5	of	of	ADP
admet-346	113	6	these	these	DET
admet-346	113	7	media	medium	NOUN
admet-346	113	8	and	and	CCONJ
admet-346	113	9	the	the	DET
admet-346	113	10	conditions	condition	NOUN
admet-346	113	11	of	of	ADP
admet-346	113	12	solubility	solubility	NOUN
admet-346	113	13	study	study	NOUN
admet-346	113	14	were	be	AUX
admet-346	113	15	not	not	PART
admet-346	113	16	described	describe	VERB
admet-346	113	17	in	in	ADP
admet-346	113	18	the	the	DET
admet-346	113	19	research	research	NOUN
admet-346	113	20	paper	paper	NOUN
admet-346	113	21	.	.	PUNCT
admet-346	114	1	besides	besides	SCONJ
admet-346	114	2	,	,	PUNCT
admet-346	114	3	we	we	PRON
admet-346	114	4	suppose	suppose	VERB
admet-346	114	5	that	that	SCONJ
admet-346	114	6	the	the	DET
admet-346	114	7	used	used	ADJ
admet-346	114	8	media	medium	NOUN
admet-346	114	9	did	do	AUX
admet-346	114	10	not	not	PART
admet-346	114	11	contain	contain	VERB
admet-346	114	12	enzymes	enzyme	NOUN
admet-346	114	13	,	,	PUNCT
admet-346	114	14	which	which	PRON
admet-346	114	15	means	mean	VERB
admet-346	114	16	sgfsp	sgfsp	NOUN
admet-346	114	17	and	and	CCONJ
admet-346	114	18	sifsp	sifsp	NOUN
admet-346	114	19	,	,	PUNCT
admet-346	114	20	due	due	ADP
admet-346	114	21	to	to	ADP
admet-346	114	22	other	other	ADJ
admet-346	114	23	procedures	procedure	NOUN
admet-346	114	24	mentioned	mention	VERB
admet-346	114	25	in	in	ADP
admet-346	114	26	the	the	DET
admet-346	114	27	paper	paper	NOUN
admet-346	114	28	.	.	PUNCT
admet-346	115	1	our	our	PRON
admet-346	115	2	solubility	solubility	NOUN
admet-346	115	3	data	datum	NOUN
admet-346	115	4	of	of	ADP
admet-346	115	5	cc	cc	PUNCT
admet-346	115	6	measured	measure	VERB
admet-346	115	7	by	by	ADP
admet-346	115	8	a	a	DET
admet-346	115	9	shake	shake	NOUN
admet-346	115	10	-	-	PUNCT
admet-346	115	11	flask	flask	NOUN
admet-346	115	12	method	method	NOUN
admet-346	115	13	in	in	ADP
admet-346	115	14	sgfsp	sgfsp	NOUN
admet-346	115	15	and	and	CCONJ
admet-346	115	16	sifsp	sifsp	PROPN
admet-346	115	17	do	do	AUX
admet-346	115	18	not	not	PART
admet-346	115	19	correspond	correspond	VERB
admet-346	115	20	with	with	ADP
admet-346	115	21	data	datum	NOUN
admet-346	115	22	by	by	ADP
admet-346	115	23	satturwar	satturwar	PROPN
admet-346	115	24	et	et	PROPN
admet-346	115	25	al	al	PROPN
admet-346	115	26	.	.	PUNCT
admet-346	116	1	[	[	X
admet-346	116	2	20	20	NUM
admet-346	116	3	]	]	PUNCT
admet-346	116	4	.	.	PUNCT
admet-346	117	1	our	our	PRON
admet-346	117	2	cc	cc	PROPN
admet-346	117	3	solubility	solubility	NOUN
admet-346	117	4	in	in	ADP
admet-346	117	5	sgfsp	sgfsp	NOUN
admet-346	117	6	is	be	AUX
admet-346	117	7	twice	twice	ADV
admet-346	117	8	as	as	ADV
admet-346	117	9	high	high	ADJ
admet-346	117	10	and	and	CCONJ
admet-346	117	11	cc	cc	NOUN
admet-346	117	12	solubility	solubility	NOUN
admet-346	117	13	in	in	ADP
admet-346	117	14	sifsp	sifsp	PROPN
admet-346	117	15	13	13	NUM
admet-346	117	16	times	time	NOUN
admet-346	117	17	as	as	ADV
admet-346	117	18	low	low	ADJ
admet-346	117	19	than	than	ADP
admet-346	117	20	satturwar	satturwar	PROPN
admet-346	117	21	’s	’s	PART
admet-346	117	22	data	data	PROPN
admet-346	117	23	.	.	PUNCT
admet-346	118	1	table	table	NOUN
admet-346	118	2	3	3	NUM
admet-346	118	3	.	.	PUNCT
admet-346	118	4	saturation	saturation	NOUN
admet-346	118	5	solubility	solubility	NOUN
admet-346	118	6	of	of	ADP
admet-346	118	7	cc	cc	PROPN
admet-346	118	8	in	in	ADP
admet-346	118	9	used	use	VERB
admet-346	118	10	media	medium	NOUN
admet-346	118	11	.	.	PUNCT
admet-346	119	1	medium	medium	ADJ
admet-346	119	2	solubility	solubility	NOUN
admet-346	119	3	of	of	ADP
admet-346	119	4	cc	cc	PROPN
admet-346	119	5	(	(	PUNCT
admet-346	119	6	µg	µg	NOUN
admet-346	119	7	/	/	SYM
admet-346	119	8	ml	ml	VERB
admet-346	119	9	)	)	PUNCT
admet-346	119	10	shortened	shorten	VERB
admet-346	119	11	test	test	NOUN
admet-346	119	12	standard	standard	ADJ
admet-346	119	13	test	test	NOUN
admet-346	119	14	(	(	PUNCT
admet-346	119	15	24	24	NUM
admet-346	119	16	-	-	PUNCT
admet-346	119	17	hour	hour	NOUN
admet-346	119	18	)	)	PUNCT
admet-346	119	19	ppt20	ppt20	PROPN
admet-346	119	20	93.00±0.10	93.00±0.10	PROPN
admet-346	119	21	fassgf	fassgf	NOUN
admet-346	119	22	0.90±0.07	0.90±0.07	PROPN
admet-346	119	23	*	*	PROPN
admet-346	119	24	1.59±0.02	1.59±0.02	NUM
admet-346	119	25	*	*	PUNCT
admet-346	120	1	*	*	PUNCT
admet-346	120	2	0.72±0.19	0.72±0.19	NUM
admet-346	120	3	sgf	sgf	PROPN
admet-346	120	4	2.76±0.46	2.76±0.46	PROPN
admet-346	120	5	*	*	PROPN
admet-346	120	6	sgfsp	sgfsp	NOUN
admet-346	120	7	1.35±0.10	1.35±0.10	PROPN
admet-346	120	8	sgftriton	sgftriton	PROPN
admet-346	120	9	0.69±0.07	0.69±0.07	PROPN
admet-346	120	10	*	*	PROPN
admet-346	120	11	6.00±0.25	6.00±0.25	NOUN
admet-346	120	12	sgfsls	sgfsls	NOUN
admet-346	120	13	147.63±0.35	147.63±0.35	PROPN
admet-346	120	14	sifsp	sifsp	PROPN
admet-346	120	15	0.65±0.01	0.65±0.01	PROPN
admet-346	120	16	fassif	fassif	VERB
admet-346	120	17	8.26±0.18	8.26±0.18	PROPN
admet-346	120	18	*	*	PUNCT
admet-346	120	19	2	2	NUM
admet-346	120	20	-	-	PUNCT
admet-346	120	21	hour	hour	NOUN
admet-346	120	22	test	test	NOUN
admet-346	120	23	*	*	PUNCT
admet-346	121	1	*	*	PUNCT
admet-346	121	2	12	12	NUM
admet-346	121	3	-	-	PUNCT
admet-346	121	4	hour	hour	NOUN
admet-346	121	5	test	test	NOUN
admet-346	121	6	results	result	NOUN
admet-346	121	7	demonstrate	demonstrate	VERB
admet-346	121	8	that	that	SCONJ
admet-346	121	9	only	only	ADV
admet-346	121	10	in	in	ADP
admet-346	121	11	the	the	DET
admet-346	121	12	media	media	NOUN
admet-346	121	13	sgfsls	sgfsls	NOUN
admet-346	121	14	(	(	PUNCT
admet-346	121	15	147.63	147.63	NUM
admet-346	121	16	µg	µg	NOUN
admet-346	121	17	/	/	SYM
admet-346	121	18	ml	ml	NOUN
admet-346	121	19	)	)	PUNCT
admet-346	121	20	and	and	CCONJ
admet-346	121	21	ppt20	ppt20	PROPN
admet-346	121	22	(	(	PUNCT
admet-346	121	23	93.00	93.00	NUM
admet-346	121	24	µg	µg	NOUN
admet-346	121	25	/	/	SYM
admet-346	121	26	ml	ml	NOUN
admet-346	121	27	)	)	PUNCT
admet-346	121	28	sink	sink	NOUN
admet-346	121	29	conditions	condition	NOUN
admet-346	121	30	for	for	ADP
admet-346	121	31	8	8	NUM
admet-346	121	32	mg	mg	NOUN
admet-346	121	33	tablets	tablet	NOUN
admet-346	121	34	of	of	ADP
admet-346	121	35	cc	cc	NOUN
admet-346	121	36	can	can	AUX
admet-346	121	37	be	be	AUX
admet-346	121	38	achieved	achieve	VERB
admet-346	121	39	in	in	ADP
admet-346	121	40	volume	volume	NOUN
admet-346	121	41	500	500	NUM
admet-346	121	42	ml	ml	NOUN
admet-346	121	43	.	.	PUNCT
admet-346	122	1	three	three	NUM
admet-346	122	2	liters	liter	NOUN
admet-346	122	3	of	of	ADP
admet-346	122	4	fassif	fassif	NOUN
admet-346	122	5	and	and	CCONJ
admet-346	122	6	four	four	NUM
admet-346	122	7	liters	liter	NOUN
admet-346	122	8	of	of	ADP
admet-346	122	9	sgftriton	sgftriton	NOUN
admet-346	122	10	were	be	AUX
admet-346	122	11	required	require	VERB
admet-346	122	12	to	to	PART
admet-346	122	13	achieve	achieve	VERB
admet-346	122	14	minimum	minimum	ADJ
admet-346	122	15	sink	sink	NOUN
admet-346	122	16	conditions	condition	NOUN
admet-346	122	17	(	(	PUNCT
admet-346	122	18	approximately	approximately	ADV
admet-346	122	19	30	30	NUM
admet-346	122	20	%	%	NOUN
admet-346	122	21	of	of	ADP
admet-346	122	22	the	the	DET
admet-346	122	23	saturation	saturation	NOUN
admet-346	122	24	concentration	concentration	NOUN
admet-346	122	25	of	of	ADP
admet-346	122	26	cc	cc	NOUN
admet-346	122	27	)	)	PUNCT
admet-346	122	28	in	in	ADP
admet-346	122	29	dissolution	dissolution	NOUN
admet-346	122	30	studies	study	NOUN
admet-346	122	31	.	.	PUNCT
admet-346	123	1	however	however	ADV
admet-346	123	2	,	,	PUNCT
admet-346	123	3	so	so	ADV
admet-346	123	4	large	large	ADJ
admet-346	123	5	volumes	volume	NOUN
admet-346	123	6	are	be	AUX
admet-346	123	7	not	not	PART
admet-346	123	8	physiologically	physiologically	ADV
admet-346	123	9	relevant	relevant	ADJ
admet-346	123	10	.	.	PUNCT
admet-346	124	1	based	base	VERB
admet-346	124	2	on	on	ADP
admet-346	124	3	solubility	solubility	NOUN
admet-346	124	4	studies	study	NOUN
admet-346	124	5	,	,	PUNCT
admet-346	124	6	it	it	PRON
admet-346	124	7	is	be	AUX
admet-346	124	8	expected	expect	VERB
admet-346	124	9	that	that	SCONJ
admet-346	124	10	in	in	ADP
admet-346	124	11	the	the	DET
admet-346	124	12	biorelevant	biorelevant	ADJ
admet-346	124	13	media	medium	NOUN
admet-346	124	14	for	for	ADP
admet-346	124	15	fasted	fast	VERB
admet-346	124	16	state	state	NOUN
admet-346	124	17	conditions	condition	NOUN
admet-346	124	18	are	be	AUX
admet-346	124	19	not	not	PART
admet-346	124	20	sufficient	sufficient	ADJ
admet-346	124	21	to	to	PART
admet-346	124	22	achieve	achieve	VERB
admet-346	124	23	complete	complete	ADJ
admet-346	124	24	dissolution	dissolution	NOUN
admet-346	124	25	of	of	ADP
admet-346	124	26	the	the	DET
admet-346	124	27	minimum	minimum	PROPN
admet-346	124	28	dose	dose	PROPN
admet-346	124	29	.	.	PUNCT
admet-346	125	1	dissolution	dissolution	PROPN
admet-346	125	2	study	study	NOUN
admet-346	125	3	the	the	DET
admet-346	125	4	dissolution	dissolution	NOUN
admet-346	125	5	properties	property	NOUN
admet-346	125	6	of	of	ADP
admet-346	125	7	cc	cc	NOUN
admet-346	125	8	are	be	AUX
admet-346	125	9	influenced	influence	VERB
admet-346	125	10	by	by	ADP
admet-346	125	11	ph	ph	NOUN
admet-346	125	12	due	due	ADP
admet-346	125	13	to	to	ADP
admet-346	125	14	the	the	DET
admet-346	125	15	ionization	ionization	NOUN
admet-346	125	16	effect	effect	NOUN
admet-346	125	17	of	of	ADP
admet-346	125	18	cc	cc	PROPN
admet-346	125	19	at	at	ADP
admet-346	125	20	phs	phs	NOUN
admet-346	125	21	above	above	ADP
admet-346	125	22	6.0	6.0	NUM
admet-346	125	23	,	,	PUNCT
admet-346	125	24	and	and	CCONJ
admet-346	125	25	also	also	ADV
admet-346	125	26	by	by	ADP
admet-346	125	27	the	the	DET
admet-346	125	28	presence	presence	NOUN
admet-346	125	29	of	of	ADP
admet-346	125	30	a	a	DET
admet-346	125	31	surfactant	surfactant	NOUN
admet-346	125	32	.	.	PUNCT
admet-346	126	1	the	the	DET
admet-346	126	2	similar	similar	ADJ
admet-346	126	3	amount	amount	NOUN
admet-346	126	4	of	of	ADP
admet-346	126	5	cc	cc	PROPN
admet-346	126	6	(	(	PUNCT
admet-346	126	7	12	12	NUM
admet-346	126	8	-	-	SYM
admet-346	126	9	13	13	NUM
admet-346	126	10	%	%	NOUN
admet-346	126	11	)	)	PUNCT
admet-346	126	12	was	be	AUX
admet-346	126	13	dissolved	dissolve	VERB
admet-346	126	14	in	in	ADP
admet-346	126	15	sgf	sgf	PROPN
admet-346	126	16	and	and	CCONJ
admet-346	126	17	fassgf	fassgf	ADJ
admet-346	126	18	media	medium	NOUN
admet-346	126	19	(	(	PUNCT
admet-346	126	20	figure	figure	NOUN
admet-346	126	21	2	2	NUM
admet-346	126	22	)	)	PUNCT
admet-346	126	23	at	at	ADP
admet-346	126	24	ph	ph	PROPN
admet-346	126	25	1.2	1.2	NUM
admet-346	126	26	and	and	CCONJ
admet-346	126	27	1.6	1.6	NUM
admet-346	126	28	,	,	PUNCT
admet-346	126	29	respectively	respectively	ADV
admet-346	126	30	.	.	PUNCT
admet-346	127	1	it	it	PRON
admet-346	127	2	was	be	AUX
admet-346	127	3	predictable	predictable	ADJ
admet-346	127	4	from	from	ADP
admet-346	127	5	the	the	DET
admet-346	127	6	results	result	NOUN
admet-346	127	7	of	of	ADP
admet-346	127	8	saturation	saturation	NOUN
admet-346	127	9	solubility	solubility	NOUN
admet-346	127	10	.	.	PUNCT
admet-346	128	1	dissolution	dissolution	PROPN
admet-346	128	2	testing	testing	NOUN
admet-346	128	3	proved	prove	VERB
admet-346	128	4	the	the	DET
admet-346	128	5	same	same	ADJ
admet-346	128	6	dissolution	dissolution	NOUN
admet-346	128	7	rate	rate	NOUN
admet-346	128	8	of	of	ADP
admet-346	128	9	cc	cc	PROPN
admet-346	128	10	.	.	PUNCT
admet-346	128	11	very	very	ADV
admet-346	128	12	small	small	ADJ
admet-346	128	13	divergence	divergence	NOUN
admet-346	128	14	between	between	ADP
admet-346	128	15	profiles	profile	NOUN
admet-346	128	16	of	of	ADP
admet-346	128	17	sgf	sgf	PROPN
admet-346	128	18	and	and	CCONJ
admet-346	128	19	fassgf	fassgf	NOUN
admet-346	128	20	is	be	AUX
admet-346	128	21	caused	cause	VERB
admet-346	128	22	by	by	ADP
admet-346	128	23	the	the	DET
admet-346	128	24	close	close	ADJ
admet-346	128	25	values	value	NOUN
admet-346	128	26	of	of	ADP
admet-346	128	27	ph	ph	NOUN
admet-346	128	28	and	and	CCONJ
admet-346	128	29	the	the	DET
admet-346	128	30	low	low	ADJ
admet-346	128	31	concentration	concentration	NOUN
admet-346	128	32	level	level	NOUN
admet-346	128	33	of	of	ADP
admet-346	128	34	the	the	DET
admet-346	128	35	natural	natural	ADJ
admet-346	128	36	surfactants	surfactant	NOUN
admet-346	128	37	in	in	ADP
admet-346	128	38	fassgf	fassgf	NOUN
admet-346	128	39	.	.	PUNCT
admet-346	129	1	despite	despite	SCONJ
admet-346	129	2	the	the	DET
admet-346	129	3	fast	fast	ADJ
admet-346	129	4	degradation	degradation	NOUN
admet-346	129	5	of	of	ADP
admet-346	129	6	cc	cc	PROPN
admet-346	129	7	at	at	ADP
admet-346	129	8	acid	acid	PROPN
admet-346	129	9	ph	ph	PROPN
admet-346	129	10	,	,	PUNCT
admet-346	129	11	the	the	DET
admet-346	129	12	decrease	decrease	NOUN
admet-346	129	13	of	of	ADP
admet-346	129	14	the	the	DET
admet-346	129	15	cc	cc	NOUN
admet-346	129	16	concentration	concentration	NOUN
admet-346	129	17	was	be	AUX
admet-346	129	18	not	not	PART
admet-346	129	19	observed	observe	VERB
admet-346	129	20	during	during	ADP
admet-346	129	21	one	one	NUM
admet-346	129	22	hour	hour	NOUN
admet-346	129	23	.	.	PUNCT
admet-346	130	1	however	however	ADV
admet-346	130	2	,	,	PUNCT
admet-346	130	3	5	5	NUM
admet-346	130	4	%	%	NOUN
admet-346	130	5	decrease	decrease	NOUN
admet-346	130	6	of	of	ADP
admet-346	130	7	the	the	DET
admet-346	130	8	cc	cc	PROPN
admet-346	130	9	concentration	concentration	NOUN
admet-346	130	10	was	be	AUX
admet-346	130	11	observed	observe	VERB
admet-346	130	12	throughout	throughout	ADP
admet-346	130	13	the	the	DET
admet-346	130	14	dissolution	dissolution	NOUN
admet-346	130	15	tests	test	NOUN
admet-346	130	16	in	in	ADP
admet-346	130	17	sgfsp	sgfsp	NOUN
admet-346	130	18	(	(	PUNCT
admet-346	130	19	figure	figure	NOUN
admet-346	130	20	3	3	NUM
admet-346	130	21	)	)	PUNCT
admet-346	130	22	.	.	PUNCT
admet-346	131	1	less	less	ADV
admet-346	131	2	considerable	considerable	ADJ
admet-346	131	3	,	,	PUNCT
admet-346	131	4	but	but	CCONJ
admet-346	131	5	still	still	ADV
admet-346	131	6	noticeable	noticeable	ADJ
admet-346	131	7	,	,	PUNCT
admet-346	131	8	0.5	0.5	NUM
admet-346	131	9	%	%	NOUN
admet-346	131	10	reduction	reduction	NOUN
admet-346	131	11	occurred	occur	VERB
admet-346	131	12	also	also	ADV
admet-346	131	13	in	in	ADP
admet-346	131	14	case	case	NOUN
admet-346	131	15	of	of	ADP
admet-346	131	16	the	the	DET
admet-346	131	17	dissolution	dissolution	NOUN
admet-346	131	18	cc	cc	PROPN
admet-346	131	19	in	in	ADP
admet-346	131	20	sifsp	sifsp	PROPN
admet-346	131	21	.	.	PUNCT
admet-346	132	1	these	these	DET
admet-346	132	2	courses	course	NOUN
admet-346	132	3	of	of	ADP
admet-346	132	4	the	the	DET
admet-346	132	5	dissolution	dissolution	ADJ
admet-346	132	6	profiles	profile	NOUN
admet-346	132	7	in	in	ADP
admet-346	132	8	sgfsp	sgfsp	NOUN
admet-346	132	9	and	and	CCONJ
admet-346	132	10	sifsp	sifsp	PROPN
admet-346	132	11	prove	prove	VERB
admet-346	132	12	the	the	DET
admet-346	132	13	extremely	extremely	ADV
admet-346	132	14	short	short	ADJ
admet-346	132	15	-	-	PUNCT
admet-346	132	16	time	time	NOUN
admet-346	132	17	stability	stability	NOUN
admet-346	132	18	of	of	ADP
admet-346	132	19	cc	cc	PROPN
admet-346	132	20	in	in	ADP
admet-346	132	21	aqueous	aqueous	ADJ
admet-346	132	22	environment	environment	NOUN
admet-346	132	23	without	without	ADP
admet-346	132	24	surfactants	surfactant	NOUN
admet-346	132	25	or	or	CCONJ
admet-346	132	26	enzymes	enzyme	NOUN
admet-346	132	27	.	.	PUNCT
admet-346	133	1	the	the	DET
admet-346	133	2	reason	reason	NOUN
admet-346	133	3	why	why	SCONJ
admet-346	133	4	the	the	DET
admet-346	133	5	medium	medium	ADJ
admet-346	133	6	sifsp	sifsp	NOUN
admet-346	133	7	instead	instead	ADV
admet-346	133	8	of	of	ADP
admet-346	133	9	sif	sif	NOUN
admet-346	133	10	was	be	AUX
admet-346	133	11	used	use	VERB
admet-346	133	12	is	be	AUX
admet-346	133	13	that	that	SCONJ
admet-346	133	14	pancreatin	pancreatin	ADJ
admet-346	133	15	coloured	colour	VERB
admet-346	133	16	the	the	DET
admet-346	133	17	medium	medium	NOUN
admet-346	133	18	and	and	CCONJ
admet-346	133	19	sif	sif	NOUN
admet-346	133	20	could	could	AUX
admet-346	133	21	not	not	PART
admet-346	133	22	be	be	AUX
admet-346	133	23	analyzed	analyze	VERB
admet-346	133	24	by	by	ADP
admet-346	133	25	a	a	DET
admet-346	133	26	spectrophotometric	spectrophotometric	ADJ
admet-346	133	27	technique	technique	NOUN
admet-346	133	28	.	.	PUNCT
admet-346	134	1	the	the	DET
admet-346	134	2	amounts	amount	NOUN
admet-346	134	3	of	of	ADP
admet-346	134	4	dissolved	dissolve	VERB
admet-346	134	5	cc	cc	NOUN
admet-346	134	6	in	in	ADP
admet-346	134	7	35	35	NUM
admet-346	134	8	minutes	minute	NOUN
admet-346	134	9	in	in	ADP
admet-346	134	10	sgf	sgf	PROPN
admet-346	134	11	(	(	PUNCT
admet-346	134	12	12	12	NUM
admet-346	134	13	%	%	NOUN
admet-346	134	14	)	)	PUNCT
admet-346	134	15	and	and	CCONJ
admet-346	134	16	sifsp	sifsp	NOUN
admet-346	134	17	(	(	PUNCT
admet-346	134	18	10	10	NUM
admet-346	134	19	%	%	NOUN
admet-346	134	20	)	)	PUNCT
admet-346	134	21	were	be	AUX
admet-346	134	22	close	close	ADJ
admet-346	134	23	to	to	ADP
admet-346	134	24	each	each	DET
admet-346	134	25	other	other	ADJ
admet-346	134	26	until	until	SCONJ
admet-346	134	27	the	the	DET
admet-346	134	28	degradation	degradation	NOUN
admet-346	134	29	process	process	NOUN
admet-346	134	30	in	in	ADP
admet-346	134	31	sifsp	sifsp	PROPN
admet-346	134	32	occured	occur	VERB
admet-346	134	33	.	.	PUNCT
admet-346	135	1	similar	similar	ADJ
admet-346	135	2	dissolution	dissolution	NOUN
admet-346	135	3	profiles	profile	NOUN
admet-346	135	4	were	be	AUX
admet-346	135	5	achieved	achieve	VERB
admet-346	135	6	in	in	ADP
admet-346	135	7	spite	spite	NOUN
admet-346	135	8	of	of	ADP
admet-346	135	9	the	the	DET
admet-346	135	10	low	low	ADJ
admet-346	135	11	ph	ph	NOUN
admet-346	135	12	value	value	NOUN
admet-346	135	13	in	in	ADP
admet-346	135	14	sgf	sgf	PROPN
admet-346	135	15	(	(	PUNCT
admet-346	135	16	sgf	sgf	NOUN
admet-346	135	17	-	-	PUNCT
admet-346	135	18	ph	ph	ADJ
admet-346	135	19	1.2	1.2	NUM
admet-346	135	20	and	and	CCONJ
admet-346	135	21	sifsp	sifsp	NOUN
admet-346	135	22	-	-	PUNCT
admet-346	135	23	ph	ph	ADJ
admet-346	135	24	6.8	6.8	NUM
admet-346	135	25	,	,	PUNCT
admet-346	135	26	the	the	DET
admet-346	135	27	highest	high	ADJ
admet-346	135	28	ph	ph	NOUN
admet-346	135	29	of	of	ADP
admet-346	135	30	the	the	DET
admet-346	135	31	used	use	VERB
admet-346	135	32	media	medium	NOUN
admet-346	135	33	)	)	PUNCT
admet-346	135	34	on	on	ADP
admet-346	135	35	the	the	DET
admet-346	135	36	one	one	NUM
admet-346	135	37	hand	hand	NOUN
admet-346	135	38	and	and	CCONJ
admet-346	135	39	the	the	DET
admet-346	135	40	low	low	ADJ
admet-346	135	41	equilibrium	equilibrium	NOUN
admet-346	135	42	solubility	solubility	NOUN
admet-346	135	43	of	of	ADP
admet-346	135	44	cc	cc	PROPN
admet-346	135	45	in	in	ADP
admet-346	135	46	sifsp	sifsp	PROPN
admet-346	135	47	on	on	ADP
admet-346	135	48	the	the	DET
admet-346	135	49	other	other	ADJ
admet-346	135	50	hand	hand	NOUN
admet-346	135	51	.	.	PUNCT
admet-346	136	1	nevertheless	nevertheless	ADV
admet-346	136	2	,	,	PUNCT
admet-346	136	3	the	the	DET
admet-346	136	4	ionization	ionization	NOUN
admet-346	136	5	of	of	ADP
admet-346	136	6	cc	cc	NOUN
admet-346	136	7	molecules	molecule	NOUN
admet-346	136	8	at	at	ADP
admet-346	136	9	phs	phs	NOUN
admet-346	136	10	above	above	ADP
admet-346	136	11	6.0	6.0	NUM
admet-346	136	12	probably	probably	ADV
admet-346	136	13	occurred	occur	VERB
admet-346	136	14	gruberová	gruberová	PROPN
admet-346	136	15	and	and	CCONJ
admet-346	136	16	kratochvil	kratochvil	PROPN
admet-346	136	17	admet	admet	PROPN
admet-346	136	18	&	&	CCONJ
admet-346	136	19	dmpk	dmpk	PROPN
admet-346	136	20	5(1	5(1	NUM
admet-346	136	21	)	)	PUNCT
admet-346	136	22	(	(	PUNCT
admet-346	136	23	2017	2017	NUM
admet-346	136	24	)	)	PUNCT
admet-346	136	25	39	39	NUM
admet-346	136	26	-	-	SYM
admet-346	136	27	46	46	NUM
admet-346	136	28	44	44	NUM
admet-346	136	29	during	during	ADP
admet-346	136	30	the	the	DET
admet-346	136	31	dissolution	dissolution	NOUN
admet-346	136	32	test	test	NOUN
admet-346	136	33	.	.	PUNCT
admet-346	137	1	the	the	DET
admet-346	137	2	ionization	ionization	NOUN
admet-346	137	3	resulted	result	VERB
admet-346	137	4	in	in	ADP
admet-346	137	5	solubility	solubility	NOUN
admet-346	137	6	increase	increase	NOUN
admet-346	137	7	and	and	CCONJ
admet-346	137	8	subsequently	subsequently	ADV
admet-346	137	9	the	the	DET
admet-346	137	10	degradation	degradation	NOUN
admet-346	137	11	of	of	ADP
admet-346	137	12	dissolved	dissolved	ADJ
admet-346	137	13	compound	compound	NOUN
admet-346	137	14	.	.	PUNCT
admet-346	138	1	figure	figure	NOUN
admet-346	138	2	2	2	NUM
admet-346	138	3	.	.	PUNCT
admet-346	138	4	dissolution	dissolution	ADJ
admet-346	138	5	profiles	profile	NOUN
admet-346	138	6	of	of	ADP
admet-346	138	7	candesartan	candesartan	ADJ
admet-346	138	8	cilexetil	cilexetil	NOUN
admet-346	138	9	in	in	ADP
admet-346	138	10	medium	medium	ADJ
admet-346	138	11	ppt20	ppt20	NOUN
admet-346	138	12	,	,	PUNCT
admet-346	138	13	fassgf	fassgf	NOUN
admet-346	138	14	,	,	PUNCT
admet-346	138	15	sgf	sgf	PROPN
admet-346	138	16	,	,	PUNCT
admet-346	138	17	sgftriton	sgftriton	PROPN
admet-346	138	18	,	,	PUNCT
admet-346	138	19	sgfsls	sgfsls	NOUN
admet-346	138	20	and	and	CCONJ
admet-346	138	21	fassif	fassif	VERB
admet-346	138	22	the	the	DET
admet-346	138	23	most	most	ADV
admet-346	138	24	promising	promising	ADJ
admet-346	138	25	medium	medium	NOUN
admet-346	138	26	for	for	ADP
admet-346	138	27	the	the	DET
admet-346	138	28	dissolution	dissolution	NOUN
admet-346	138	29	testing	testing	NOUN
admet-346	138	30	of	of	ADP
admet-346	138	31	cc	cc	PROPN
admet-346	138	32	was	be	AUX
admet-346	138	33	considered	consider	VERB
admet-346	138	34	fassif	fassif	NOUN
admet-346	138	35	,	,	PUNCT
admet-346	138	36	the	the	DET
admet-346	138	37	medium	medium	NOUN
admet-346	138	38	with	with	ADP
admet-346	138	39	ph	ph	PROPN
admet-346	138	40	6.5	6.5	NUM
admet-346	138	41	and	and	CCONJ
admet-346	138	42	the	the	DET
admet-346	138	43	natural	natural	ADJ
admet-346	138	44	surfactants	surfactant	NOUN
admet-346	138	45	taurocholate	taurocholate	NOUN
admet-346	138	46	sodium	sodium	NOUN
admet-346	138	47	and	and	CCONJ
admet-346	138	48	lecithin	lecithin	NOUN
admet-346	138	49	.	.	PUNCT
admet-346	139	1	however	however	ADV
admet-346	139	2	,	,	PUNCT
admet-346	139	3	the	the	DET
admet-346	139	4	cc	cc	PROPN
admet-346	139	5	solubility	solubility	NOUN
admet-346	139	6	in	in	ADP
admet-346	139	7	this	this	DET
admet-346	139	8	medium	medium	NOUN
admet-346	139	9	was	be	AUX
admet-346	139	10	not	not	PART
admet-346	139	11	sufficient	sufficient	ADJ
admet-346	139	12	.	.	PUNCT
admet-346	140	1	for	for	ADP
admet-346	140	2	this	this	DET
admet-346	140	3	reason	reason	NOUN
admet-346	140	4	,	,	PUNCT
admet-346	140	5	sink	sink	NOUN
admet-346	140	6	conditions	condition	NOUN
admet-346	140	7	were	be	AUX
admet-346	140	8	not	not	PART
admet-346	140	9	obtained	obtain	VERB
admet-346	140	10	in	in	ADP
admet-346	140	11	the	the	DET
admet-346	140	12	paddle	paddle	NOUN
admet-346	140	13	apparatus	apparatus	NOUN
admet-346	140	14	and	and	CCONJ
admet-346	140	15	therefore	therefore	ADV
admet-346	140	16	,	,	PUNCT
admet-346	140	17	the	the	DET
admet-346	140	18	dissolution	dissolution	NOUN
admet-346	140	19	rate	rate	NOUN
admet-346	140	20	and	and	CCONJ
admet-346	140	21	extent	extent	NOUN
admet-346	140	22	of	of	ADP
admet-346	140	23	the	the	DET
admet-346	140	24	cc	cc	PROPN
admet-346	140	25	solubility	solubility	NOUN
admet-346	140	26	(	(	PUNCT
admet-346	140	27	46	46	NUM
admet-346	140	28	%	%	NOUN
admet-346	140	29	)	)	PUNCT
admet-346	140	30	was	be	AUX
admet-346	140	31	reduced	reduce	VERB
admet-346	140	32	(	(	PUNCT
admet-346	140	33	figure	figure	NOUN
admet-346	140	34	2	2	NUM
admet-346	140	35	)	)	PUNCT
admet-346	140	36	.	.	PUNCT
admet-346	141	1	figure	figure	VERB
admet-346	141	2	3	3	NUM
admet-346	141	3	.	.	PUNCT
admet-346	141	4	dissolution	dissolution	ADJ
admet-346	141	5	profiles	profile	NOUN
admet-346	141	6	of	of	ADP
admet-346	141	7	candesartan	candesartan	ADJ
admet-346	141	8	cilexetil	cilexetil	NOUN
admet-346	141	9	in	in	ADP
admet-346	141	10	medium	medium	ADJ
admet-346	141	11	sgf	sgf	PROPN
admet-346	141	12	,	,	PUNCT
admet-346	141	13	sgfsp	sgfsp	NOUN
admet-346	141	14	and	and	CCONJ
admet-346	141	15	sifsp	sifsp	PROPN
admet-346	141	16	the	the	DET
admet-346	141	17	biorelevant	biorelevant	ADJ
admet-346	141	18	dissolution	dissolution	NOUN
admet-346	141	19	profiles	profile	NOUN
admet-346	141	20	of	of	ADP
admet-346	141	21	cc	cc	NOUN
admet-346	141	22	are	be	AUX
admet-346	141	23	not	not	PART
admet-346	141	24	accordant	accordant	ADJ
admet-346	141	25	with	with	ADP
admet-346	141	26	the	the	DET
admet-346	141	27	dissolution	dissolution	ADJ
admet-346	141	28	profiles	profile	NOUN
admet-346	141	29	of	of	ADP
admet-346	141	30	cc	cc	PROPN
admet-346	141	31	in	in	ADP
admet-346	141	32	the	the	DET
admet-346	141	33	media	medium	NOUN
admet-346	141	34	with	with	ADP
admet-346	141	35	the	the	DET
admet-346	141	36	artificial	artificial	ADJ
admet-346	141	37	surfactants	surfactant	NOUN
admet-346	141	38	,	,	PUNCT
admet-346	141	39	especially	especially	ADV
admet-346	141	40	with	with	ADP
admet-346	141	41	the	the	DET
admet-346	141	42	surfactant	surfactant	ADJ
admet-346	141	43	tween	tween	NOUN
admet-346	141	44	20	20	NUM
admet-346	141	45	and	and	CCONJ
admet-346	141	46	sodium	sodium	NOUN
admet-346	141	47	lauryl	lauryl	NOUN
admet-346	141	48	sulfate	sulfate	NOUN
admet-346	141	49	(	(	PUNCT
admet-346	141	50	figure	figure	NOUN
admet-346	141	51	2	2	NUM
admet-346	141	52	)	)	PUNCT
admet-346	141	53	.	.	PUNCT
admet-346	142	1	it	it	PRON
admet-346	142	2	was	be	AUX
admet-346	142	3	found	find	VERB
admet-346	142	4	for	for	ADP
admet-346	142	5	cc	cc	PROPN
admet-346	142	6	that	that	DET
admet-346	142	7	solubilization	solubilization	NOUN
admet-346	142	8	plays	play	VERB
admet-346	142	9	much	much	ADV
admet-346	142	10	more	more	ADV
admet-346	142	11	determining	determine	VERB
admet-346	142	12	role	role	NOUN
admet-346	142	13	in	in	ADP
admet-346	142	14	solubility	solubility	NOUN
admet-346	142	15	than	than	ADP
admet-346	142	16	ionization	ionization	NOUN
admet-346	142	17	.	.	PUNCT
admet-346	143	1	the	the	DET
admet-346	143	2	solubility	solubility	NOUN
admet-346	143	3	and	and	CCONJ
admet-346	143	4	dissolution	dissolution	NOUN
admet-346	143	5	rate	rate	NOUN
admet-346	143	6	of	of	ADP
admet-346	143	7	cc	cc	PROPN
admet-346	143	8	in	in	ADP
admet-346	143	9	the	the	DET
admet-346	143	10	media	medium	NOUN
admet-346	143	11	ppt20	ppt20	NOUN
admet-346	143	12	(	(	PUNCT
admet-346	143	13	96	96	NUM
admet-346	143	14	%	%	NOUN
admet-346	143	15	)	)	PUNCT
admet-346	143	16	and	and	CCONJ
admet-346	143	17	sgfsls	sgfsls	NOUN
admet-346	143	18	(	(	PUNCT
admet-346	143	19	72	72	NUM
admet-346	143	20	%	%	NOUN
admet-346	143	21	)	)	PUNCT
admet-346	143	22	are	be	AUX
admet-346	143	23	considerately	considerately	ADV
admet-346	143	24	higher	high	ADJ
admet-346	143	25	.	.	PUNCT
admet-346	144	1	in	in	ADP
admet-346	144	2	the	the	DET
admet-346	144	3	case	case	NOUN
admet-346	144	4	of	of	ADP
admet-346	144	5	sgfsls	sgfsls	NOUN
admet-346	144	6	it	it	PRON
admet-346	144	7	is	be	AUX
admet-346	144	8	despite	despite	SCONJ
admet-346	144	9	the	the	DET
admet-346	144	10	low	low	ADJ
admet-346	144	11	ph	ph	NOUN
admet-346	144	12	value	value	NOUN
admet-346	144	13	(	(	PUNCT
admet-346	144	14	ph	ph	NOUN
admet-346	144	15	1.2	1.2	NUM
admet-346	144	16	)	)	PUNCT
admet-346	144	17	.	.	PUNCT
admet-346	145	1	the	the	DET
admet-346	145	2	increase	increase	NOUN
admet-346	145	3	of	of	ADP
admet-346	145	4	the	the	DET
admet-346	145	5	solubility	solubility	NOUN
admet-346	145	6	in	in	ADP
admet-346	145	7	the	the	DET
admet-346	145	8	medium	medium	NOUN
admet-346	145	9	containing	contain	VERB
admet-346	145	10	the	the	DET
admet-346	145	11	surfactant	surfactant	ADJ
admet-346	145	12	triton	triton	PROPN
admet-346	145	13	x	x	SYM
admet-346	145	14	®	®	PROPN
admet-346	145	15	-100	-100	PROPN
admet-346	145	16	is	be	AUX
admet-346	145	17	not	not	PART
admet-346	145	18	so	so	ADV
admet-346	145	19	pronounced	pronounce	VERB
admet-346	145	20	(	(	PUNCT
admet-346	145	21	31	31	NUM
admet-346	145	22	%	%	NOUN
admet-346	145	23	)	)	PUNCT
admet-346	145	24	.	.	PUNCT
admet-346	146	1	this	this	PRON
admet-346	146	2	indicates	indicate	VERB
admet-346	146	3	admet	admet	PROPN
admet-346	146	4	&	&	CCONJ
admet-346	146	5	dmpk	dmpk	PROPN
admet-346	146	6	5(1	5(1	NUM
admet-346	146	7	)	)	PUNCT
admet-346	146	8	(	(	PUNCT
admet-346	146	9	2017	2017	NUM
admet-346	146	10	)	)	PUNCT
admet-346	146	11	39	39	NUM
admet-346	146	12	-	-	SYM
admet-346	146	13	46	46	NUM
admet-346	146	14	biorelevant	biorelevant	NOUN
admet-346	146	15	dissolution	dissolution	NOUN
admet-346	146	16	of	of	ADP
admet-346	146	17	candesartan	candesartan	PROPN
admet-346	146	18	cilexetil	cilexetil	PROPN
admet-346	146	19	doi	doi	PROPN
admet-346	146	20	:	:	PUNCT
admet-346	146	21	10.5599	10.5599	NUM
admet-346	146	22	/	/	SYM
admet-346	146	23	admet.5.1.346	admet.5.1.346	NUM
admet-346	146	24	45	45	NUM
admet-346	146	25	how	how	SCONJ
admet-346	146	26	the	the	DET
admet-346	146	27	choice	choice	NOUN
admet-346	146	28	of	of	ADP
admet-346	146	29	a	a	DET
admet-346	146	30	surfactant	surfactant	NOUN
admet-346	146	31	influences	influence	VERB
admet-346	146	32	the	the	DET
admet-346	146	33	resulting	result	VERB
admet-346	146	34	solubility	solubility	NOUN
admet-346	146	35	of	of	ADP
admet-346	146	36	a	a	DET
admet-346	146	37	drug	drug	NOUN
admet-346	146	38	.	.	PUNCT
admet-346	147	1	it	it	PRON
admet-346	147	2	is	be	AUX
admet-346	147	3	evident	evident	ADJ
admet-346	147	4	that	that	SCONJ
admet-346	147	5	the	the	DET
admet-346	147	6	application	application	NOUN
admet-346	147	7	of	of	ADP
admet-346	147	8	dissolution	dissolution	ADJ
admet-346	147	9	media	medium	NOUN
admet-346	147	10	with	with	ADP
admet-346	147	11	artificial	artificial	ADJ
admet-346	147	12	surfactants	surfactant	NOUN
admet-346	147	13	would	would	AUX
admet-346	147	14	lead	lead	VERB
admet-346	147	15	to	to	ADP
admet-346	147	16	false	false	ADJ
admet-346	147	17	positive	positive	ADJ
admet-346	147	18	results	result	NOUN
admet-346	147	19	because	because	SCONJ
admet-346	147	20	artificial	artificial	ADJ
admet-346	147	21	surfactants	surfactant	NOUN
admet-346	147	22	induce	induce	VERB
admet-346	147	23	greater	great	ADJ
admet-346	147	24	solubilization	solubilization	NOUN
admet-346	147	25	effects	effect	NOUN
admet-346	147	26	than	than	ADP
admet-346	147	27	what	what	PRON
admet-346	147	28	would	would	AUX
admet-346	147	29	be	be	AUX
admet-346	147	30	physiologically	physiologically	ADV
admet-346	147	31	relevant	relevant	ADJ
admet-346	147	32	.	.	PUNCT
admet-346	148	1	conclusions	conclusion	NOUN
admet-346	148	2	the	the	DET
admet-346	148	3	need	need	NOUN
admet-346	148	4	for	for	ADP
admet-346	148	5	in	in	ADP
admet-346	148	6	vitro	vitro	X
admet-346	148	7	test	test	NOUN
admet-346	148	8	which	which	PRON
admet-346	148	9	mimics	mimic	VERB
admet-346	148	10	in	in	ADP
admet-346	148	11	vivo	vivo	ADJ
admet-346	148	12	conditions	condition	NOUN
admet-346	148	13	of	of	ADP
admet-346	148	14	the	the	DET
admet-346	148	15	gastrointestinal	gastrointestinal	ADJ
admet-346	148	16	tract	tract	NOUN
admet-346	148	17	led	lead	VERB
admet-346	148	18	to	to	ADP
admet-346	148	19	the	the	DET
admet-346	148	20	development	development	NOUN
admet-346	148	21	of	of	ADP
admet-346	148	22	physiologically	physiologically	ADV
admet-346	148	23	relevant	relevant	ADJ
admet-346	148	24	dissolution	dissolution	NOUN
admet-346	148	25	media	medium	NOUN
admet-346	148	26	.	.	PUNCT
admet-346	149	1	the	the	DET
admet-346	149	2	dissolution	dissolution	NOUN
admet-346	149	3	of	of	ADP
admet-346	149	4	the	the	DET
admet-346	149	5	poorly	poorly	ADV
admet-346	149	6	soluble	soluble	ADJ
admet-346	149	7	drug	drug	NOUN
admet-346	149	8	cc	cc	PROPN
admet-346	149	9	was	be	AUX
admet-346	149	10	studied	study	VERB
admet-346	149	11	in	in	ADP
admet-346	149	12	different	different	ADJ
admet-346	149	13	type	type	NOUN
admet-346	149	14	of	of	ADP
admet-346	149	15	dissolution	dissolution	ADJ
admet-346	149	16	media	medium	NOUN
admet-346	149	17	:	:	PUNCT
admet-346	149	18	the	the	DET
admet-346	149	19	compendial	compendial	ADJ
admet-346	149	20	medium	medium	NOUN
admet-346	149	21	(	(	PUNCT
admet-346	149	22	ppt20	ppt20	PROPN
admet-346	149	23	)	)	PUNCT
admet-346	149	24	commonly	commonly	ADV
admet-346	149	25	used	use	VERB
admet-346	149	26	for	for	ADP
admet-346	149	27	quality	quality	NOUN
admet-346	149	28	control	control	NOUN
admet-346	149	29	,	,	PUNCT
admet-346	149	30	the	the	DET
admet-346	149	31	artificial	artificial	ADJ
admet-346	149	32	fluids	fluid	NOUN
admet-346	149	33	with	with	ADP
admet-346	149	34	the	the	DET
admet-346	149	35	synthetic	synthetic	ADJ
admet-346	149	36	surfactants	surfactant	NOUN
admet-346	149	37	(	(	PUNCT
admet-346	149	38	sgftriton	sgftriton	PROPN
admet-346	149	39	,	,	PUNCT
admet-346	149	40	sgfsls	sgfsls	NOUN
admet-346	149	41	)	)	PUNCT
admet-346	149	42	or	or	CCONJ
admet-346	149	43	without	without	ADP
admet-346	149	44	them	they	PRON
admet-346	149	45	(	(	PUNCT
admet-346	149	46	sgf	sgf	PROPN
admet-346	149	47	,	,	PUNCT
admet-346	149	48	sgfsp	sgfsp	NOUN
admet-346	149	49	,	,	PUNCT
admet-346	149	50	sifsp	sifsp	PROPN
admet-346	149	51	)	)	PUNCT
admet-346	149	52	and	and	CCONJ
admet-346	149	53	the	the	DET
admet-346	149	54	fasted	fasted	ADJ
admet-346	149	55	state	state	NOUN
admet-346	149	56	simulating	simulate	VERB
admet-346	149	57	biorelevant	biorelevant	ADJ
admet-346	149	58	media	medium	NOUN
admet-346	149	59	(	(	PUNCT
admet-346	149	60	fassgf	fassgf	NOUN
admet-346	149	61	,	,	PUNCT
admet-346	149	62	fassif	fassif	NOUN
admet-346	149	63	)	)	PUNCT
admet-346	149	64	.	.	PUNCT
admet-346	150	1	in	in	ADP
admet-346	150	2	this	this	DET
admet-346	150	3	study	study	NOUN
admet-346	150	4	,	,	PUNCT
admet-346	150	5	the	the	DET
admet-346	150	6	dissolution	dissolution	NOUN
admet-346	150	7	media	medium	NOUN
admet-346	150	8	that	that	PRON
admet-346	150	9	are	be	AUX
admet-346	150	10	possible	possible	ADJ
admet-346	150	11	to	to	PART
admet-346	150	12	analyse	analyse	VERB
admet-346	150	13	by	by	ADP
admet-346	150	14	a	a	DET
admet-346	150	15	uv	uv	NOUN
admet-346	150	16	-	-	PUNCT
admet-346	150	17	vis	vis	X
admet-346	150	18	spectrophotometer	spectrophotometer	NOUN
admet-346	150	19	were	be	AUX
admet-346	150	20	examined	examine	VERB
admet-346	150	21	.	.	PUNCT
admet-346	151	1	consequently	consequently	ADV
admet-346	151	2	,	,	PUNCT
admet-346	151	3	dissolution	dissolution	NOUN
admet-346	151	4	tests	test	NOUN
admet-346	151	5	with	with	ADP
admet-346	151	6	medium	medium	ADJ
admet-346	151	7	sif	sif	NOUN
admet-346	151	8	and	and	CCONJ
admet-346	151	9	biorelevant	biorelevant	ADJ
admet-346	151	10	media	medium	NOUN
admet-346	151	11	simulated	simulate	VERB
admet-346	151	12	fed	fed	PROPN
admet-346	151	13	state	state	NOUN
admet-346	151	14	(	(	PUNCT
admet-346	151	15	fessgf	fessgf	NOUN
admet-346	151	16	and	and	CCONJ
admet-346	151	17	fessif	fessif	NOUN
admet-346	151	18	)	)	PUNCT
admet-346	151	19	were	be	AUX
admet-346	151	20	not	not	PART
admet-346	151	21	carried	carry	VERB
admet-346	151	22	out	out	ADP
admet-346	151	23	.	.	PUNCT
admet-346	152	1	the	the	DET
admet-346	152	2	amount	amount	NOUN
admet-346	152	3	of	of	ADP
admet-346	152	4	dissolved	dissolve	VERB
admet-346	152	5	cc	cc	NOUN
admet-346	152	6	in	in	ADP
admet-346	152	7	the	the	DET
admet-346	152	8	biorelevant	biorelevant	NOUN
admet-346	152	9	media	medium	NOUN
admet-346	152	10	was	be	AUX
admet-346	152	11	significantly	significantly	ADV
admet-346	152	12	lower	low	ADJ
admet-346	152	13	than	than	ADP
admet-346	152	14	the	the	DET
admet-346	152	15	amount	amount	NOUN
admet-346	152	16	of	of	ADP
admet-346	152	17	cc	cc	PART
admet-346	152	18	dissolved	dissolve	VERB
admet-346	152	19	during	during	ADP
admet-346	152	20	tests	test	NOUN
admet-346	152	21	with	with	ADP
admet-346	152	22	the	the	DET
admet-346	152	23	media	medium	NOUN
admet-346	152	24	containing	contain	VERB
admet-346	152	25	the	the	DET
admet-346	152	26	synthetic	synthetic	ADJ
admet-346	152	27	surfactants	surfactant	NOUN
admet-346	152	28	.	.	PUNCT
admet-346	153	1	whereas	whereas	SCONJ
admet-346	153	2	the	the	DET
admet-346	153	3	biorelevant	biorelevant	NOUN
admet-346	153	4	media	medium	NOUN
admet-346	153	5	contain	contain	VERB
admet-346	153	6	natural	natural	ADJ
admet-346	153	7	surfactants	surfactant	NOUN
admet-346	153	8	as	as	ADP
admet-346	153	9	an	an	DET
admet-346	153	10	alternative	alternative	NOUN
admet-346	153	11	to	to	ADP
admet-346	153	12	the	the	DET
admet-346	153	13	non	non	ADJ
admet-346	153	14	-	-	ADJ
admet-346	153	15	physiologically	physiologically	ADV
admet-346	153	16	relevant	relevant	ADJ
admet-346	153	17	surfactants	surfactant	NOUN
admet-346	153	18	,	,	PUNCT
admet-346	153	19	the	the	DET
admet-346	153	20	dissolution	dissolution	ADJ
admet-346	153	21	profiles	profile	NOUN
admet-346	153	22	of	of	ADP
admet-346	153	23	cc	cc	PROPN
admet-346	153	24	corresponded	correspond	VERB
admet-346	153	25	with	with	ADP
admet-346	153	26	the	the	DET
admet-346	153	27	in	in	ADP
admet-346	153	28	vivo	vivo	ADJ
admet-346	153	29	behavior	behavior	NOUN
admet-346	153	30	of	of	ADP
admet-346	153	31	cc	cc	NOUN
admet-346	153	32	closely	closely	ADV
admet-346	153	33	in	in	ADP
admet-346	153	34	fassgf	fassgf	NOUN
admet-346	153	35	and	and	CCONJ
admet-346	153	36	fassif	fassif	NOUN
admet-346	153	37	.	.	PUNCT
admet-346	154	1	the	the	DET
admet-346	154	2	poor	poor	ADJ
admet-346	154	3	solubility	solubility	NOUN
admet-346	154	4	and	and	CCONJ
admet-346	154	5	stability	stability	NOUN
admet-346	154	6	of	of	ADP
admet-346	154	7	cc	cc	PROPN
admet-346	154	8	in	in	ADP
admet-346	154	9	the	the	DET
admet-346	154	10	biorelevant	biorelevant	NOUN
admet-346	154	11	media	medium	NOUN
admet-346	154	12	resulted	result	VERB
admet-346	154	13	in	in	ADP
admet-346	154	14	its	its	PRON
admet-346	154	15	low	low	ADJ
admet-346	154	16	bioavailability	bioavailability	NOUN
admet-346	154	17	.	.	PUNCT
admet-346	155	1	the	the	DET
admet-346	155	2	results	result	NOUN
admet-346	155	3	can	can	AUX
admet-346	155	4	be	be	AUX
admet-346	155	5	utilized	utilize	VERB
admet-346	155	6	as	as	ADP
admet-346	155	7	an	an	DET
admet-346	155	8	example	example	NOUN
admet-346	155	9	that	that	SCONJ
admet-346	155	10	the	the	DET
admet-346	155	11	biorelevant	biorelevant	ADJ
admet-346	155	12	media	medium	NOUN
admet-346	155	13	are	be	AUX
admet-346	155	14	useful	useful	ADJ
admet-346	155	15	to	to	PART
admet-346	155	16	forecast	forecast	VERB
admet-346	155	17	the	the	DET
admet-346	155	18	oral	oral	ADJ
admet-346	155	19	absorption	absorption	NOUN
admet-346	155	20	of	of	ADP
admet-346	155	21	a	a	DET
admet-346	155	22	bcs	bcs	NOUN
admet-346	155	23	class	class	NOUN
admet-346	155	24	ii	ii	NOUN
admet-346	155	25	drug	drug	NOUN
admet-346	155	26	.	.	PUNCT
admet-346	156	1	list	list	NOUN
admet-346	156	2	of	of	ADP
admet-346	156	3	abbreviations	abbreviation	NOUN
admet-346	156	4	cc	cc	PROPN
admet-346	156	5	candesartan	candesartan	PROPN
admet-346	156	6	cilexetil	cilexetil	PROPN
admet-346	156	7	fassgf	fassgf	PROPN
admet-346	156	8	fasted	fast	VERB
admet-346	156	9	state	state	NOUN
admet-346	156	10	simulated	simulate	VERB
admet-346	156	11	gastric	gastric	ADJ
admet-346	156	12	fluid	fluid	NOUN
admet-346	156	13	fassif	fassif	NOUN
admet-346	156	14	fasted	fast	VERB
admet-346	156	15	state	state	NOUN
admet-346	156	16	simulated	simulate	VERB
admet-346	156	17	intestinal	intestinal	ADJ
admet-346	156	18	fluid	fluid	NOUN
admet-346	156	19	fessgf	fessgf	NOUN
admet-346	156	20	fed	feed	VERB
admet-346	156	21	state	state	PROPN
admet-346	156	22	simulated	simulate	VERB
admet-346	156	23	gastric	gastric	ADJ
admet-346	156	24	fluid	fluid	NOUN
admet-346	156	25	fessif	fessif	NOUN
admet-346	156	26	fed	feed	VERB
admet-346	156	27	state	state	NOUN
admet-346	156	28	simulated	simulate	VERB
admet-346	156	29	intestinal	intestinal	ADJ
admet-346	156	30	fluid	fluid	ADJ
admet-346	156	31	git	git	NOUN
admet-346	156	32	gastrointestinal	gastrointestinal	ADJ
admet-346	156	33	tract	tract	NOUN
admet-346	156	34	ppt20	ppt20	ADJ
admet-346	156	35	phosphate	phosphate	NOUN
admet-346	156	36	buffer	buffer	NOUN
admet-346	156	37	with	with	ADP
admet-346	156	38	surfactant	surfactant	ADJ
admet-346	156	39	tween	tween	NOUN
admet-346	156	40	20	20	NUM
admet-346	156	41	sgf	sgf	PROPN
admet-346	156	42	simulated	simulate	VERB
admet-346	156	43	gastric	gastric	ADJ
admet-346	156	44	fluid	fluid	NOUN
admet-346	156	45	sgfsp	sgfsp	NOUN
admet-346	157	1	simulated	simulate	VERB
admet-346	157	2	gastric	gastric	ADJ
admet-346	157	3	fluid	fluid	ADJ
admet-346	157	4	sine	sine	ADJ
admet-346	157	5	pepsin	pepsin	NOUN
admet-346	157	6	sgfsls	sgfsls	NOUN
admet-346	157	7	simulated	simulate	VERB
admet-346	157	8	gastric	gastric	ADJ
admet-346	157	9	fluid	fluid	NOUN
admet-346	157	10	without	without	ADP
admet-346	157	11	enzyme	enzyme	NOUN
admet-346	157	12	but	but	CCONJ
admet-346	157	13	with	with	ADP
admet-346	157	14	surfactant	surfactant	ADJ
admet-346	157	15	sodium	sodium	NOUN
admet-346	157	16	lauryl	lauryl	NOUN
admet-346	157	17	sulfate	sulfate	NOUN
admet-346	157	18	sgftritin	sgftritin	ADJ
admet-346	157	19	simulated	simulate	VERB
admet-346	157	20	gastric	gastric	ADJ
admet-346	157	21	fluid	fluid	NOUN
admet-346	157	22	without	without	ADP
admet-346	157	23	enzyme	enzyme	NOUN
admet-346	157	24	but	but	CCONJ
admet-346	157	25	with	with	ADP
admet-346	157	26	surfactant	surfactant	ADJ
admet-346	157	27	tritonx	tritonx	NOUN
admet-346	157	28	®	®	NOUN
admet-346	157	29	100	100	NUM
admet-346	157	30	sif	sif	NOUN
admet-346	157	31	simulated	simulate	VERB
admet-346	157	32	intestinal	intestinal	ADJ
admet-346	157	33	fluid	fluid	NOUN
admet-346	157	34	sifsp	sifsp	NOUN
admet-346	157	35	simulated	simulate	VERB
admet-346	157	36	intestinal	intestinal	ADJ
admet-346	157	37	fluid	fluid	NOUN
admet-346	157	38	sine	sine	NOUN
admet-346	157	39	pancreatin	pancreatin	ADJ
admet-346	157	40	acknowledgements	acknowledgement	NOUN
admet-346	157	41	:	:	PUNCT
admet-346	157	42	financial	financial	ADJ
admet-346	157	43	support	support	NOUN
admet-346	157	44	from	from	ADP
admet-346	157	45	specific	specific	ADJ
admet-346	157	46	university	university	NOUN
admet-346	157	47	research	research	NOUN
admet-346	157	48	(	(	PUNCT
admet-346	157	49	msmt	msmt	INTJ
admet-346	157	50	no	no	DET
admet-346	157	51	20	20	NUM
admet-346	157	52	-	-	PUNCT
admet-346	157	53	svv/2016	svv/2016	NOUN
admet-346	157	54	)	)	PUNCT
admet-346	157	55	and	and	CCONJ
admet-346	157	56	teva	teva	PROPN
admet-346	157	57	czech	czech	PROPN
admet-346	157	58	industries	industry	NOUN
admet-346	157	59	s.r.o	s.r.o	PROPN
admet-346	157	60	.	.	PUNCT
admet-346	158	1	references	reference	NOUN
admet-346	158	2	[	[	X
admet-346	158	3	1	1	X
admet-346	158	4	]	]	PUNCT
admet-346	158	5	j.	j.	PROPN
admet-346	158	6	b.	b.	PROPN
admet-346	158	7	dressman	dressman	PROPN
admet-346	158	8	,	,	PUNCT
admet-346	158	9	c.	c.	PROPN
admet-346	158	10	reppas	reppas	PROPN
admet-346	158	11	,	,	PUNCT
admet-346	158	12	european	european	PROPN
admet-346	158	13	journal	journal	PROPN
admet-346	158	14	of	of	ADP
admet-346	158	15	pharmaceutical	pharmaceutical	ADJ
admet-346	158	16	sciences	science	NOUN
admet-346	158	17	11	11	NUM
admet-346	158	18	(	(	PUNCT
admet-346	158	19	2000	2000	NUM
admet-346	158	20	)	)	PUNCT
admet-346	158	21	s73	s73	NOUN
admet-346	158	22	-	-	PUNCT
admet-346	158	23	s80	s80	NOUN
admet-346	158	24	.	.	PUNCT
admet-346	159	1	[	[	X
admet-346	159	2	2	2	X
admet-346	159	3	]	]	PUNCT
admet-346	159	4	s.	s.	PROPN
admet-346	159	5	klein	klein	PROPN
admet-346	159	6	,	,	PUNCT
admet-346	159	7	aaps	aaps	PROPN
admet-346	159	8	journal	journal	PROPN
admet-346	159	9	12	12	NUM
admet-346	159	10	(	(	PUNCT
admet-346	159	11	2010	2010	NUM
admet-346	159	12	)	)	PUNCT
admet-346	159	13	397	397	NUM
admet-346	159	14	-	-	SYM
admet-346	159	15	406	406	NUM
admet-346	159	16	.	.	PUNCT
admet-346	160	1	[	[	X
admet-346	160	2	3	3	X
admet-346	160	3	]	]	X
admet-346	160	4	j.	j.	PROPN
admet-346	160	5	b.	b.	PROPN
admet-346	160	6	dressman	dressman	PROPN
admet-346	160	7	,	,	PUNCT
admet-346	160	8	dissolution	dissolution	PROPN
admet-346	160	9	technologies	technology	NOUN
admet-346	160	10	6	6	NUM
admet-346	160	11	(	(	PUNCT
admet-346	160	12	2014	2014	NUM
admet-346	160	13	)	)	PUNCT
admet-346	160	14	6	6	NUM
admet-346	160	15	-	-	SYM
admet-346	160	16	10	10	NUM
admet-346	160	17	.	.	PUNCT
admet-346	161	1	gruberová	gruberová	PROPN
admet-346	161	2	and	and	CCONJ
admet-346	161	3	kratochvil	kratochvil	PROPN
admet-346	161	4	admet	admet	PROPN
admet-346	161	5	&	&	CCONJ
admet-346	161	6	dmpk	dmpk	PROPN
admet-346	161	7	5(1	5(1	NUM
admet-346	161	8	)	)	PUNCT
admet-346	161	9	(	(	PUNCT
admet-346	161	10	2017	2017	NUM
admet-346	161	11	)	)	PUNCT
admet-346	161	12	39	39	NUM
admet-346	161	13	-	-	SYM
admet-346	161	14	46	46	NUM
admet-346	161	15	46	46	NUM
admet-346	161	16	[	[	X
admet-346	161	17	4	4	X
admet-346	161	18	]	]	X
admet-346	161	19	e.	e.	PROPN
admet-346	161	20	galia	galia	PROPN
admet-346	161	21	,	,	PUNCT
admet-346	161	22	e.	e.	PROPN
admet-346	161	23	nicolaides	nicolaides	PROPN
admet-346	161	24	,	,	PUNCT
admet-346	161	25	d.	d.	PROPN
admet-346	161	26	hörter	hörter	PROPN
admet-346	161	27	,	,	PUNCT
admet-346	161	28	r.	r.	PROPN
admet-346	161	29	löbenberg	löbenberg	PROPN
admet-346	161	30	,	,	PUNCT
admet-346	161	31	c.	c.	PROPN
admet-346	161	32	reppas	reppas	PROPN
admet-346	161	33	,	,	PUNCT
admet-346	161	34	j.	j.	PROPN
admet-346	161	35	b.	b.	PROPN
admet-346	161	36	dressman	dressman	PROPN
admet-346	161	37	,	,	PUNCT
admet-346	161	38	pharmaceutical	pharmaceutical	ADJ
admet-346	161	39	research	research	NOUN
admet-346	161	40	15	15	NUM
admet-346	161	41	(	(	PUNCT
admet-346	161	42	1998	1998	NUM
admet-346	161	43	)	)	PUNCT
admet-346	161	44	698	698	NUM
admet-346	161	45	-	-	SYM
admet-346	161	46	705	705	NUM
admet-346	161	47	.	.	PUNCT
admet-346	162	1	[	[	X
admet-346	162	2	5	5	X
admet-346	162	3	]	]	PUNCT
admet-346	162	4	j.	j.	PROPN
admet-346	162	5	b.	b.	PROPN
admet-346	162	6	dressman	dressman	PROPN
admet-346	162	7	,	,	PUNCT
admet-346	162	8	g.	g.	PROPN
admet-346	162	9	l.	l.	PROPN
admet-346	162	10	amidon	amidon	PROPN
admet-346	162	11	,	,	PUNCT
admet-346	162	12	c.	c.	PROPN
admet-346	162	13	reppas	reppas	PROPN
admet-346	162	14	,	,	PUNCT
admet-346	162	15	v.	v.	ADP
admet-346	162	16	p.	p.	NOUN
admet-346	162	17	shah	shah	NOUN
admet-346	162	18	,	,	PUNCT
admet-346	162	19	pharmaceutical	pharmaceutical	ADJ
admet-346	162	20	research	research	NOUN
admet-346	162	21	15	15	NUM
admet-346	162	22	(	(	PUNCT
admet-346	162	23	1998	1998	NUM
admet-346	162	24	)	)	PUNCT
admet-346	162	25	11	11	NUM
admet-346	162	26	-	-	SYM
admet-346	162	27	22	22	NUM
admet-346	162	28	.	.	PUNCT
admet-346	163	1	[	[	X
admet-346	163	2	6	6	NUM
admet-346	163	3	]	]	PUNCT
admet-346	163	4	e.	e.	PROPN
admet-346	163	5	galia	galia	PROPN
admet-346	163	6	,	,	PUNCT
admet-346	163	7	j.	j.	PROPN
admet-346	163	8	horton	horton	PROPN
admet-346	163	9	,	,	PUNCT
admet-346	163	10	j.	j.	PROPN
admet-346	163	11	b.	b.	PROPN
admet-346	163	12	dressman	dressman	PROPN
admet-346	163	13	,	,	PUNCT
admet-346	163	14	pharmaceutical	pharmaceutical	ADJ
admet-346	163	15	research	research	NOUN
admet-346	163	16	16	16	NUM
admet-346	163	17	(	(	PUNCT
admet-346	163	18	1999	1999	NUM
admet-346	163	19	)	)	PUNCT
admet-346	163	20	1871	1871	NUM
admet-346	163	21	-	-	SYM
admet-346	163	22	1875	1875	NUM
admet-346	163	23	.	.	PUNCT
admet-346	164	1	[	[	X
admet-346	164	2	7	7	X
admet-346	164	3	]	]	X
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admet-346	164	5	vertzoni	vertzoni	PROPN
admet-346	164	6	,	,	PUNCT
admet-346	164	7	e.	e.	PROPN
admet-346	164	8	pastelli	pastelli	PROPN
admet-346	164	9	,	,	PUNCT
admet-346	164	10	d.	d.	PROPN
admet-346	164	11	psachoulias	psachoulias	PROPN
admet-346	164	12	,	,	PUNCT
admet-346	164	13	l.	l.	PROPN
admet-346	164	14	kalantzi	kalantzi	PROPN
admet-346	164	15	,	,	PUNCT
admet-346	164	16	c.	c.	PROPN
admet-346	164	17	reppas	reppas	PROPN
admet-346	164	18	,	,	PUNCT
admet-346	164	19	pharmaceutical	pharmaceutical	ADJ
admet-346	164	20	research	research	NOUN
admet-346	164	21	24	24	NUM
admet-346	164	22	(	(	PUNCT
admet-346	164	23	2007	2007	NUM
admet-346	164	24	)	)	PUNCT
admet-346	164	25	909	909	NUM
admet-346	164	26	-	-	SYM
admet-346	164	27	917	917	NUM
admet-346	164	28	.	.	PUNCT
admet-346	165	1	[	[	X
admet-346	165	2	8	8	NUM
admet-346	165	3	]	]	X
admet-346	165	4	m.	m.	NOUN
admet-346	165	5	vertzoni	vertzoni	PROPN
admet-346	165	6	,	,	PUNCT
admet-346	165	7	j.	j.	PROPN
admet-346	165	8	b.	b.	PROPN
admet-346	165	9	dressman	dressman	PROPN
admet-346	165	10	,	,	PUNCT
admet-346	165	11	j.	j.	PROPN
admet-346	165	12	butler	butler	PROPN
admet-346	165	13	,	,	PUNCT
admet-346	165	14	j.	j.	PROPN
admet-346	165	15	hempenstall	hempenstall	PROPN
admet-346	165	16	,	,	PUNCT
admet-346	165	17	c.	c.	PROPN
admet-346	165	18	reppas	reppas	PROPN
admet-346	165	19	,	,	PUNCT
admet-346	165	20	european	european	PROPN
admet-346	165	21	journal	journal	PROPN
admet-346	165	22	of	of	ADP
admet-346	165	23	pharmaceutics	pharmaceutic	NOUN
admet-346	165	24	and	and	CCONJ
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admet-346	165	26	60	60	NUM
admet-346	165	27	(	(	PUNCT
admet-346	165	28	2005	2005	NUM
admet-346	165	29	)	)	PUNCT
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admet-346	165	31	-	-	SYM
admet-346	165	32	417	417	NUM
admet-346	165	33	.	.	PUNCT
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admet-346	166	2	9	9	NUM
admet-346	166	3	]	]	X
admet-346	166	4	e.	e.	PROPN
admet-346	166	5	jantratid	jantratid	PROPN
admet-346	166	6	,	,	PUNCT
admet-346	166	7	n.	n.	PROPN
admet-346	166	8	janssen	janssen	PROPN
admet-346	166	9	,	,	PUNCT
admet-346	166	10	c.	c.	PROPN
admet-346	166	11	reppas	reppas	PROPN
admet-346	166	12	,	,	PUNCT
admet-346	166	13	j.	j.	PROPN
admet-346	166	14	b.	b.	PROPN
admet-346	166	15	dressman	dressman	PROPN
admet-346	166	16	,	,	PUNCT
admet-346	166	17	pharmaceutical	pharmaceutical	ADJ
admet-346	166	18	research	research	NOUN
admet-346	166	19	25	25	NUM
admet-346	166	20	(	(	PUNCT
admet-346	166	21	2008	2008	NUM
admet-346	166	22	)	)	PUNCT
admet-346	166	23	1663	1663	NUM
admet-346	166	24	-	-	SYM
admet-346	166	25	1675	1675	NUM
admet-346	166	26	.	.	PUNCT
admet-346	167	1	[	[	X
admet-346	167	2	10	10	NUM
admet-346	167	3	]	]	PUNCT
admet-346	167	4	k.	k.	PROPN
admet-346	167	5	takács	takács	PROPN
admet-346	167	6	-	-	PUNCT
admet-346	167	7	novák	novák	PROPN
admet-346	167	8	,	,	PUNCT
admet-346	167	9	v.	v.	X
admet-346	167	10	szöke	szöke	PROPN
admet-346	167	11	,	,	PUNCT
admet-346	167	12	g.	g.	PROPN
admet-346	167	13	völgyi	völgyi	PROPN
admet-346	167	14	,	,	PUNCT
admet-346	167	15	p.	p.	NOUN
admet-346	167	16	horváth	horváth	PROPN
admet-346	167	17	,	,	PUNCT
admet-346	167	18	journal	journal	NOUN
admet-346	167	19	of	of	ADP
admet-346	167	20	pharmaceutical	pharmaceutical	NOUN
admet-346	167	21	and	and	CCONJ
admet-346	167	22	biomedical	biomedical	ADJ
admet-346	167	23	analysis	analysis	NOUN
admet-346	167	24	83	83	NUM
admet-346	167	25	(	(	PUNCT
admet-346	167	26	2013	2013	NUM
admet-346	167	27	)	)	PUNCT
admet-346	167	28	279	279	NUM
admet-346	167	29	-	-	SYM
admet-346	167	30	285	285	NUM
admet-346	167	31	.	.	PUNCT
admet-346	168	1	[	[	X
admet-346	168	2	11	11	NUM
admet-346	168	3	]	]	PUNCT
admet-346	168	4	k.	k.	PROPN
admet-346	168	5	j.	j.	PROPN
admet-346	168	6	frank	frank	PROPN
admet-346	168	7	,	,	PUNCT
admet-346	168	8	u.	u.	PROPN
admet-346	168	9	westendt	westendt	PROPN
admet-346	168	10	,	,	PUNCT
admet-346	168	11	k.	k.	PROPN
admet-346	168	12	m.	m.	PROPN
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admet-346	168	14	,	,	PUNCT
admet-346	168	15	p.	p.	PROPN
admet-346	168	16	hölig	hölig	PROPN
admet-346	168	17	,	,	PUNCT
admet-346	168	18	j.	j.	PROPN
admet-346	168	19	rosenberg	rosenberg	PROPN
admet-346	168	20	,	,	PUNCT
admet-346	168	21	m.	m.	PROPN
admet-346	168	22	mägerlein	mägerlein	PROPN
admet-346	168	23	,	,	PUNCT
admet-346	168	24	m.	m.	PROPN
admet-346	168	25	brandl	brandl	PROPN
admet-346	168	26	,	,	PUNCT
admet-346	168	27	g.	g.	PROPN
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admet-346	168	29	,	,	PUNCT
admet-346	168	30	european	european	PROPN
admet-346	168	31	journal	journal	PROPN
admet-346	168	32	of	of	ADP
admet-346	168	33	pharmaceutical	pharmaceutical	PROPN
admet-346	168	34	sciences	science	NOUN
admet-346	168	35	47	47	NUM
admet-346	168	36	(	(	PUNCT
admet-346	168	37	2012	2012	NUM
admet-346	168	38	)	)	PUNCT
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admet-346	168	40	-	-	SYM
admet-346	168	41	20	20	NUM
admet-346	168	42	.	.	PUNCT
admet-346	169	1	[	[	X
admet-346	169	2	12	12	NUM
admet-346	169	3	]	]	PUNCT
admet-346	169	4	j.	j.	PROPN
admet-346	169	5	b.	b.	PROPN
admet-346	169	6	dressman	dressman	PROPN
admet-346	169	7	,	,	PUNCT
admet-346	169	8	m.	m.	PROPN
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admet-346	169	10	,	,	PUNCT
admet-346	169	11	l.	l.	PROPN
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admet-346	169	13	,	,	PUNCT
admet-346	169	14	c.	c.	PROPN
admet-346	169	15	reppas	reppas	PROPN
admet-346	169	16	,	,	PUNCT
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admet-346	169	22	(	(	PUNCT
admet-346	169	23	2007	2007	NUM
admet-346	169	24	)	)	PUNCT
admet-346	169	25	591602	591602	NUM
admet-346	169	26	.	.	PUNCT
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admet-346	170	3	]	]	PUNCT
admet-346	170	4	e.	e.	PROPN
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admet-346	170	6	kostewicz	kostewicz	PROPN
admet-346	170	7	,	,	PUNCT
admet-346	170	8	u.	u.	PROPN
admet-346	170	9	brauns	brauns	PROPN
admet-346	170	10	,	,	PUNCT
admet-346	170	11	r.	r.	PROPN
admet-346	170	12	becker	becker	PROPN
admet-346	170	13	,	,	PUNCT
admet-346	170	14	j.	j.	PROPN
admet-346	170	15	b.	b.	PROPN
admet-346	170	16	dressman	dressman	PROPN
admet-346	170	17	,	,	PUNCT
admet-346	170	18	pharmaceutical	pharmaceutical	ADJ
admet-346	170	19	research	research	NOUN
admet-346	170	20	19	19	NUM
admet-346	170	21	(	(	PUNCT
admet-346	170	22	2002	2002	NUM
admet-346	170	23	)	)	PUNCT
admet-346	170	24	345	345	NUM
admet-346	170	25	-	-	SYM
admet-346	170	26	349	349	NUM
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admet-346	171	1	[	[	X
admet-346	171	2	14	14	NUM
admet-346	171	3	]	]	PUNCT
admet-346	171	4	b.	b.	PROPN
admet-346	171	5	abrahamsson	abrahamsson	PROPN
admet-346	171	6	,	,	PUNCT
admet-346	171	7	j.	j.	PROPN
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admet-346	171	9	,	,	PUNCT
admet-346	171	10	http://patentscope.wipo.int/search/en/wo2008030161	http://patentscope.wipo.int/search/en/wo2008030161	ADJ
admet-346	171	11	(	(	PUNCT
admet-346	171	12	2008	2008	NUM
admet-346	171	13	)	)	PUNCT
admet-346	171	14	.	.	PUNCT
admet-346	172	1	[	[	X
admet-346	172	2	15	15	NUM
admet-346	172	3	]	]	X
admet-346	172	4	m.	m.	NOUN
admet-346	172	5	burnier	burnier	NOUN
admet-346	172	6	,	,	PUNCT
admet-346	172	7	circulation	circulation	NOUN
admet-346	172	8	103	103	NUM
admet-346	172	9	(	(	PUNCT
admet-346	172	10	2001	2001	NUM
admet-346	172	11	)	)	PUNCT
admet-346	172	12	904	904	NUM
admet-346	172	13	-	-	SYM
admet-346	172	14	912	912	NUM
admet-346	172	15	.	.	PUNCT
admet-346	173	1	[	[	X
admet-346	173	2	16	16	NUM
admet-346	173	3	]	]	X
admet-346	173	4	e.	e.	PROPN
admet-346	173	5	cagigal	cagigal	PROPN
admet-346	173	6	,	,	PUNCT
admet-346	173	7	l.	l.	PROPN
admet-346	173	8	gonzáles	gonzáles	PROPN
admet-346	173	9	,	,	PUNCT
admet-346	173	10	r.	r.	PROPN
admet-346	173	11	m.	m.	PROPN
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admet-346	173	13	,	,	PUNCT
admet-346	173	14	r.	r.	PROPN
admet-346	173	15	m.	m.	PROPN
admet-346	173	16	jiménez	jiménez	PROPN
admet-346	173	17	,	,	PUNCT
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admet-346	173	19	of	of	ADP
admet-346	173	20	pharmaceutical	pharmaceutical	NOUN
admet-346	173	21	and	and	CCONJ
admet-346	173	22	biomedical	biomedical	ADJ
admet-346	173	23	analysis	analysis	NOUN
admet-346	173	24	26	26	NUM
admet-346	173	25	(	(	PUNCT
admet-346	173	26	2001	2001	NUM
admet-346	173	27	)	)	PUNCT
admet-346	173	28	477	477	NUM
admet-346	173	29	-	-	SYM
admet-346	173	30	486	486	NUM
admet-346	173	31	.	.	PUNCT
admet-346	174	1	[	[	X
admet-346	174	2	17	17	NUM
admet-346	174	3	]	]	X
admet-346	174	4	u.s	u.s	PROPN
admet-346	174	5	.	.	PROPN
admet-346	174	6	food	food	PROPN
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admet-346	174	10	,	,	PUNCT
admet-346	174	11	http://www.accessdata.fda.gov/scripts/cder/dissolution/dsp_getalldata.cfm	http://www.accessdata.fda.gov/scripts/cder/dissolution/dsp_getalldata.cfm	X
admet-346	174	12	(	(	PUNCT
admet-346	174	13	1	1	NUM
admet-346	174	14	.	.	NOUN
admet-346	174	15	9	9	NUM
admet-346	174	16	.	.	NUM
admet-346	174	17	2014	2014	NUM
admet-346	174	18	)	)	PUNCT
admet-346	174	19	.	.	PUNCT
admet-346	175	1	[	[	X
admet-346	175	2	18	18	NUM
admet-346	175	3	]	]	PUNCT
admet-346	175	4	k.	k.	PROPN
admet-346	175	5	hoppe	hoppe	PROPN
admet-346	175	6	,	,	PUNCT
admet-346	175	7	m.	m.	NOUN
admet-346	175	8	sznitowska	sznitowska	PROPN
admet-346	175	9	,	,	PUNCT
admet-346	175	10	aaps	aap	NOUN
admet-346	175	11	pharmscitech	pharmscitech	VERB
admet-346	175	12	15	15	NUM
admet-346	175	13	(	(	PUNCT
admet-346	175	14	2014	2014	NUM
admet-346	175	15	)	)	PUNCT
admet-346	175	16	1116	1116	NUM
admet-346	175	17	-	-	SYM
admet-346	175	18	1125	1125	NUM
admet-346	175	19	.	.	PUNCT
admet-346	176	1	[	[	X
admet-346	176	2	19	19	NUM
admet-346	176	3	]	]	X
admet-346	176	4	e.	e.	PROPN
admet-346	176	5	baka	baka	PROPN
admet-346	176	6	,	,	PUNCT
admet-346	176	7	j.	j.	PROPN
admet-346	176	8	e.	e.	PROPN
admet-346	176	9	a.	a.	PROPN
admet-346	176	10	corner	corner	PROPN
admet-346	176	11	,	,	PUNCT
admet-346	176	12	k.	k.	PROPN
admet-346	176	13	takács	takács	PROPN
admet-346	176	14	-	-	PUNCT
admet-346	176	15	novák	novák	PROPN
admet-346	176	16	,	,	PUNCT
admet-346	176	17	journal	journal	NOUN
admet-346	176	18	of	of	ADP
admet-346	176	19	pharmaceutical	pharmaceutical	NOUN
admet-346	176	20	and	and	CCONJ
admet-346	176	21	biomedical	biomedical	ADJ
admet-346	176	22	analysis	analysis	NOUN
admet-346	176	23	46	46	NUM
admet-346	176	24	(	(	PUNCT
admet-346	176	25	2008	2008	NUM
admet-346	176	26	)	)	PUNCT
admet-346	176	27	355	355	NUM
admet-346	176	28	-	-	SYM
admet-346	176	29	341	341	NUM
admet-346	176	30	.	.	PUNCT
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admet-346	177	2	20	20	NUM
admet-346	177	3	]	]	X
admet-346	177	4	p.	p.	NOUN
admet-346	177	5	satturwar	satturwar	PROPN
admet-346	177	6	,	,	PUNCT
admet-346	177	7	m.	m.	NOUN
admet-346	177	8	n.	n.	PROPN
admet-346	177	9	eddone	eddone	PROPN
admet-346	177	10	,	,	PUNCT
admet-346	177	11	f.	f.	PROPN
admet-346	177	12	ravenelle	ravenelle	PROPN
admet-346	177	13	,	,	PUNCT
admet-346	177	14	j.-c	j.-c	PROPN
admet-346	177	15	.	.	PUNCT
admet-346	178	1	leroux	leroux	PROPN
admet-346	178	2	,	,	PUNCT
admet-346	178	3	european	european	PROPN
admet-346	178	4	journal	journal	PROPN
admet-346	178	5	of	of	ADP
admet-346	178	6	pharmaceutics	pharmaceutic	NOUN
admet-346	178	7	and	and	CCONJ
admet-346	178	8	biopharmaceutics	biopharmaceutic	NOUN
admet-346	178	9	65	65	NUM
admet-346	178	10	(	(	PUNCT
admet-346	178	11	2007	2007	NUM
admet-346	178	12	)	)	PUNCT
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admet-346	178	14	-	-	SYM
admet-346	178	15	387	387	NUM
admet-346	178	16	.	.	PUNCT
admet-346	179	1	©	©	SYM
admet-346	179	2	2017	2017	NUM
admet-346	179	3	by	by	ADP
admet-346	179	4	the	the	DET
admet-346	179	5	authors	author	NOUN
admet-346	179	6	;	;	PUNCT
admet-346	179	7	licensee	licensee	PROPN
admet-346	179	8	iapc	iapc	PROPN
admet-346	179	9	,	,	PUNCT
admet-346	179	10	zagreb	zagreb	PROPN
admet-346	179	11	,	,	PUNCT
admet-346	179	12	croatia	croatia	PROPN
admet-346	179	13	.	.	PUNCT
admet-346	180	1	this	this	DET
admet-346	180	2	article	article	NOUN
admet-346	180	3	is	be	AUX
admet-346	180	4	an	an	DET
admet-346	180	5	open	open	ADJ
admet-346	180	6	-	-	PUNCT
admet-346	180	7	access	access	NOUN
admet-346	180	8	article	article	NOUN
admet-346	180	9	distributed	distribute	VERB
admet-346	180	10	under	under	ADP
admet-346	180	11	the	the	DET
admet-346	180	12	terms	term	NOUN
admet-346	180	13	and	and	CCONJ
admet-346	180	14	conditions	condition	NOUN
admet-346	180	15	of	of	ADP
admet-346	180	16	the	the	DET
admet-346	180	17	creative	creative	ADJ
admet-346	180	18	commons	common	NOUN
admet-346	180	19	attribution	attribution	NOUN
admet-346	180	20	license	license	NOUN
admet-346	180	21	(	(	PUNCT
admet-346	180	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	NOUN
admet-346	180	23	)	)	PUNCT
admet-346	180	24	http://patentscope.wipo.int/search/en/wo2008030161	http://patentscope.wipo.int/search/en/wo2008030161	ADJ
admet-346	180	25	http://www.accessdata.fda.gov/scripts/cder/dissolution/dsp_getalldata.cfm	http://www.accessdata.fda.gov/scripts/cder/dissolution/dsp_getalldata.cfm	SYM
admet-346	180	26	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN