id	sid	tid	token	lemma	pos
admet-400	1	1	association	association	NOUN
admet-400	1	2	of	of	ADP
admet-400	1	3	vancomycin	vancomycin	PROPN
admet-400	1	4	with	with	ADP
admet-400	1	5	lipid	lipid	NOUN
admet-400	1	6	vesicles	vesicle	NOUN
admet-400	1	7	doi	doi	NOUN
admet-400	1	8	:	:	PUNCT
admet-400	1	9	10.5599	10.5599	NUM
admet-400	1	10	/	/	SYM
admet-400	1	11	admet.5.3.400	admet.5.3.400	PROPN
admet-400	1	12	183	183	NUM
admet-400	1	13	admet	admet	X
admet-400	1	14	&	&	CCONJ
admet-400	1	15	dmpk	dmpk	PROPN
admet-400	1	16	5(3	5(3	NUM
admet-400	1	17	)	)	PUNCT
admet-400	1	18	(	(	PUNCT
admet-400	1	19	2017	2017	NUM
admet-400	1	20	)	)	PUNCT
admet-400	1	21	183	183	NUM
admet-400	1	22	-	-	SYM
admet-400	1	23	191	191	NUM
admet-400	1	24	;	;	PUNCT
admet-400	1	25	doi	doi	NOUN
admet-400	1	26	:	:	PUNCT
admet-400	1	27	http://dx.doi.org/10.5599/admet.5.3.400	http://dx.doi.org/10.5599/admet.5.3.400	ADP
admet-400	1	28	open	open	ADJ
admet-400	1	29	access	access	NOUN
admet-400	1	30	:	:	PUNCT
admet-400	1	31	issn	issn	PROPN
admet-400	1	32	:	:	PUNCT
admet-400	1	33	1848	1848	NUM
admet-400	1	34	-	-	SYM
admet-400	1	35	7718	7718	NUM
admet-400	1	36	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-400	1	37	original	original	ADJ
admet-400	1	38	scientific	scientific	ADJ
admet-400	1	39	paper	paper	NOUN
admet-400	1	40	association	association	NOUN
admet-400	1	41	of	of	ADP
admet-400	1	42	vancomycin	vancomycin	PROPN
admet-400	1	43	with	with	ADP
admet-400	1	44	lipid	lipid	ADJ
admet-400	1	45	vesicles	vesicle	NOUN
admet-400	1	46	xiaohui	xiaohui	PROPN
admet-400	1	47	hu	hu	PROPN
admet-400	1	48	and	and	CCONJ
admet-400	1	49	kin	kin	PROPN
admet-400	1	50	yip	yip	PROPN
admet-400	1	51	tam	tam	PROPN
admet-400	1	52	*	*	PUNCT
admet-400	1	53	drug	drug	PROPN
admet-400	1	54	development	development	NOUN
admet-400	1	55	core	core	NOUN
admet-400	1	56	,	,	PUNCT
admet-400	1	57	faculty	faculty	NOUN
admet-400	1	58	of	of	ADP
admet-400	1	59	health	health	NOUN
admet-400	1	60	sciences	sciences	PROPN
admet-400	1	61	,	,	PUNCT
admet-400	1	62	university	university	NOUN
admet-400	1	63	of	of	ADP
admet-400	1	64	macau	macau	PROPN
admet-400	1	65	,	,	PUNCT
admet-400	1	66	macau	macau	PROPN
admet-400	1	67	s.a.r	s.a.r	PROPN
admet-400	1	68	.	.	PUNCT
admet-400	1	69	,	,	PUNCT
admet-400	1	70	china	china	PROPN
admet-400	1	71	*	*	PUNCT
admet-400	1	72	corresponding	correspond	VERB
admet-400	1	73	author	author	NOUN
admet-400	1	74	:	:	PUNCT
admet-400	1	75	e	e	NOUN
admet-400	1	76	-	-	NOUN
admet-400	1	77	mail	mail	NOUN
admet-400	1	78	:	:	PUNCT
admet-400	1	79	kintam@umac.mo	kintam@umac.mo	PROPN
admet-400	1	80	;	;	PUNCT
admet-400	1	81	tel	tel	PROPN
admet-400	1	82	.	.	PUNCT
admet-400	1	83	:	:	PUNCT
admet-400	2	1	+853	+853	NOUN
admet-400	2	2	-	-	PUNCT
admet-400	2	3	88224988	88224988	NUM
admet-400	2	4	;	;	PUNCT
admet-400	2	5	fax	fax	NOUN
admet-400	2	6	:	:	PUNCT
admet-400	2	7	+835	+835	PROPN
admet-400	2	8	-	-	PUNCT
admet-400	2	9	88222314	88222314	NUM
admet-400	2	10	received	receive	VERB
admet-400	2	11	:	:	PUNCT
admet-400	2	12	june	june	PROPN
admet-400	2	13	15	15	NUM
admet-400	2	14	,	,	PUNCT
admet-400	2	15	2017	2017	NUM
admet-400	2	16	;	;	PUNCT
admet-400	2	17	revised	revise	VERB
admet-400	2	18	:	:	PUNCT
admet-400	2	19	july	july	PROPN
admet-400	2	20	22	22	NUM
admet-400	2	21	,	,	PUNCT
admet-400	2	22	2017	2017	NUM
admet-400	2	23	;	;	PUNCT
admet-400	2	24	published	publish	VERB
admet-400	2	25	:	:	PUNCT
admet-400	2	26	september	september	PROPN
admet-400	2	27	29	29	NUM
admet-400	2	28	,	,	PUNCT
admet-400	2	29	2017	2017	NUM
admet-400	2	30	abstract	abstract	ADJ
admet-400	2	31	antibiotics	antibiotic	NOUN
admet-400	2	32	play	play	VERB
admet-400	2	33	a	a	DET
admet-400	2	34	pivotal	pivotal	ADJ
admet-400	2	35	role	role	NOUN
admet-400	2	36	in	in	ADP
admet-400	2	37	modern	modern	ADJ
admet-400	2	38	medicine	medicine	NOUN
admet-400	2	39	for	for	ADP
admet-400	2	40	the	the	DET
admet-400	2	41	treatment	treatment	NOUN
admet-400	2	42	of	of	ADP
admet-400	2	43	bacterial	bacterial	ADJ
admet-400	2	44	infection	infection	NOUN
admet-400	2	45	in	in	ADP
admet-400	2	46	patients	patient	NOUN
admet-400	2	47	.	.	PUNCT
admet-400	3	1	membrane	membrane	NOUN
admet-400	3	2	defines	define	NOUN
admet-400	3	3	the	the	DET
admet-400	3	4	boundary	boundary	NOUN
admet-400	3	5	between	between	ADP
admet-400	3	6	single	single	ADJ
admet-400	3	7	cell	cell	NOUN
admet-400	3	8	and	and	CCONJ
admet-400	3	9	its	its	PRON
admet-400	3	10	environment	environment	NOUN
admet-400	3	11	and	and	CCONJ
admet-400	3	12	is	be	AUX
admet-400	3	13	a	a	DET
admet-400	3	14	main	main	ADJ
admet-400	3	15	target	target	NOUN
admet-400	3	16	for	for	ADP
admet-400	3	17	antibacterial	antibacterial	ADJ
admet-400	3	18	agents	agent	NOUN
admet-400	3	19	.	.	PUNCT
admet-400	4	1	to	to	PART
admet-400	4	2	better	well	ADV
admet-400	4	3	understand	understand	VERB
admet-400	4	4	the	the	DET
admet-400	4	5	mechanism	mechanism	NOUN
admet-400	4	6	of	of	ADP
admet-400	4	7	antibiotics	antibiotic	NOUN
admet-400	4	8	action	action	NOUN
admet-400	4	9	on	on	ADP
admet-400	4	10	microbes	microbe	NOUN
admet-400	4	11	,	,	PUNCT
admet-400	4	12	we	we	PRON
admet-400	4	13	utilized	utilize	VERB
admet-400	4	14	liposome	liposome	NOUN
admet-400	4	15	as	as	ADP
admet-400	4	16	membrane	membrane	NOUN
admet-400	4	17	mimic	mimic	ADJ
admet-400	4	18	model	model	NOUN
admet-400	4	19	to	to	PART
admet-400	4	20	study	study	VERB
admet-400	4	21	antibiotics	antibiotic	NOUN
admet-400	4	22	interaction	interaction	NOUN
admet-400	4	23	with	with	ADP
admet-400	4	24	bacterial	bacterial	ADJ
admet-400	4	25	membrane	membrane	NOUN
admet-400	4	26	by	by	ADP
admet-400	4	27	variety	variety	NOUN
admet-400	4	28	of	of	ADP
admet-400	4	29	biophysical	biophysical	ADJ
admet-400	4	30	methods	method	NOUN
admet-400	4	31	.	.	PUNCT
admet-400	5	1	isothermal	isothermal	ADJ
admet-400	5	2	calorimetry	calorimetry	NOUN
admet-400	5	3	and	and	CCONJ
admet-400	5	4	fluorescence	fluorescence	NOUN
admet-400	5	5	photometry	photometry	NOUN
admet-400	5	6	experiments	experiment	NOUN
admet-400	5	7	were	be	AUX
admet-400	5	8	performed	perform	VERB
admet-400	5	9	to	to	PART
admet-400	5	10	examine	examine	VERB
admet-400	5	11	interaction	interaction	NOUN
admet-400	5	12	between	between	ADP
admet-400	5	13	antibiotics	antibiotic	NOUN
admet-400	5	14	and	and	CCONJ
admet-400	5	15	liposome	liposome	NOUN
admet-400	5	16	.	.	PUNCT
admet-400	6	1	we	we	PRON
admet-400	6	2	found	find	VERB
admet-400	6	3	that	that	SCONJ
admet-400	6	4	vancomycin	vancomycin	PROPN
admet-400	6	5	,	,	PUNCT
admet-400	6	6	one	one	NUM
admet-400	6	7	of	of	ADP
admet-400	6	8	the	the	DET
admet-400	6	9	most	most	ADV
admet-400	6	10	important	important	ADJ
admet-400	6	11	antibiotics	antibiotic	NOUN
admet-400	6	12	for	for	ADP
admet-400	6	13	the	the	DET
admet-400	6	14	treatment	treatment	NOUN
admet-400	6	15	of	of	ADP
admet-400	6	16	serious	serious	ADJ
admet-400	6	17	infections	infection	NOUN
admet-400	6	18	by	by	ADP
admet-400	6	19	gram	gram	NOUN
admet-400	6	20	-	-	PUNCT
admet-400	6	21	positive	positive	ADJ
admet-400	6	22	bacteria	bacteria	NOUN
admet-400	6	23	,	,	PUNCT
admet-400	6	24	binds	bind	VERB
admet-400	6	25	to	to	ADP
admet-400	6	26	the	the	DET
admet-400	6	27	liposome	liposome	NOUN
admet-400	6	28	.	.	PUNCT
admet-400	7	1	the	the	DET
admet-400	7	2	association	association	NOUN
admet-400	7	3	between	between	ADP
admet-400	7	4	the	the	DET
admet-400	7	5	drug	drug	NOUN
admet-400	7	6	and	and	CCONJ
admet-400	7	7	the	the	DET
admet-400	7	8	liposome	liposome	NOUN
admet-400	7	9	does	do	AUX
admet-400	7	10	not	not	PART
admet-400	7	11	involve	involve	VERB
admet-400	7	12	the	the	DET
admet-400	7	13	tail	tail	NOUN
admet-400	7	14	part	part	NOUN
admet-400	7	15	of	of	ADP
admet-400	7	16	the	the	DET
admet-400	7	17	lipids	lipid	NOUN
admet-400	7	18	.	.	PUNCT
admet-400	8	1	moreover	moreover	ADV
admet-400	8	2	,	,	PUNCT
admet-400	8	3	the	the	DET
admet-400	8	4	binding	bind	VERB
admet-400	8	5	affinity	affinity	NOUN
admet-400	8	6	increases	increase	NOUN
admet-400	8	7	along	along	ADV
admet-400	8	8	with	with	ADP
admet-400	8	9	the	the	DET
admet-400	8	10	increment	increment	NOUN
admet-400	8	11	of	of	ADP
admet-400	8	12	liposome	liposome	NOUN
admet-400	8	13	size	size	NOUN
admet-400	8	14	.	.	PUNCT
admet-400	9	1	of	of	ADP
admet-400	9	2	three	three	NUM
admet-400	9	3	major	major	ADJ
admet-400	9	4	lipid	lipid	NOUN
admet-400	9	5	components	component	NOUN
admet-400	9	6	,	,	PUNCT
admet-400	9	7	phosphatidylglycerol	phosphatidylglycerol	PROPN
admet-400	9	8	is	be	AUX
admet-400	9	9	the	the	DET
admet-400	9	10	preferential	preferential	ADJ
admet-400	9	11	target	target	NOUN
admet-400	9	12	for	for	ADP
admet-400	9	13	vancomycin	vancomycin	PROPN
admet-400	9	14	binding	bind	VERB
admet-400	9	15	.	.	PUNCT
admet-400	10	1	we	we	PRON
admet-400	10	2	also	also	ADV
admet-400	10	3	showed	show	VERB
admet-400	10	4	that	that	SCONJ
admet-400	10	5	vancomycin	vancomycin	PROPN
admet-400	10	6	associates	associate	NOUN
admet-400	10	7	with	with	ADP
admet-400	10	8	vesicle	vesicle	NOUN
admet-400	10	9	derived	derive	VERB
admet-400	10	10	from	from	ADP
admet-400	10	11	staphylococcus	staphylococcus	NOUN
admet-400	10	12	aureus	aureus	NOUN
admet-400	10	13	membrane	membrane	NOUN
admet-400	10	14	in	in	ADP
admet-400	10	15	a	a	DET
admet-400	10	16	similar	similar	ADJ
admet-400	10	17	manner	manner	NOUN
admet-400	10	18	as	as	SCONJ
admet-400	10	19	the	the	DET
admet-400	10	20	binding	binding	NOUN
admet-400	10	21	to	to	PART
admet-400	10	22	liposome	liposome	VERB
admet-400	10	23	.	.	PUNCT
admet-400	11	1	our	our	PRON
admet-400	11	2	data	datum	NOUN
admet-400	11	3	suggested	suggest	VERB
admet-400	11	4	that	that	SCONJ
admet-400	11	5	vancomycin	vancomycin	PROPN
admet-400	11	6	associates	associate	NOUN
admet-400	11	7	with	with	ADP
admet-400	11	8	bacterial	bacterial	ADJ
admet-400	11	9	membrane	membrane	NOUN
admet-400	11	10	through	through	ADP
admet-400	11	11	direct	direct	ADJ
admet-400	11	12	interaction	interaction	NOUN
admet-400	11	13	with	with	ADP
admet-400	11	14	lipid	lipid	ADJ
admet-400	11	15	head	head	NOUN
admet-400	11	16	groups	group	NOUN
admet-400	11	17	with	with	ADP
admet-400	11	18	the	the	DET
admet-400	11	19	extent	extent	NOUN
admet-400	11	20	of	of	ADP
admet-400	11	21	the	the	DET
admet-400	11	22	association	association	NOUN
admet-400	11	23	depending	depend	VERB
admet-400	11	24	very	very	ADV
admet-400	11	25	much	much	ADV
admet-400	11	26	on	on	ADP
admet-400	11	27	specific	specific	ADJ
admet-400	11	28	type	type	NOUN
admet-400	11	29	of	of	ADP
admet-400	11	30	lipids	lipid	NOUN
admet-400	11	31	and	and	CCONJ
admet-400	11	32	curvature	curvature	NOUN
admet-400	11	33	of	of	ADP
admet-400	11	34	local	local	ADJ
admet-400	11	35	membrane	membrane	NOUN
admet-400	11	36	structure	structure	NOUN
admet-400	11	37	.	.	PUNCT
admet-400	12	1	keywords	keyword	NOUN
admet-400	12	2	liposome	liposome	VERB
admet-400	12	3	;	;	PUNCT
admet-400	12	4	membrane	membrane	NOUN
admet-400	12	5	;	;	PUNCT
admet-400	12	6	binding	bind	VERB
admet-400	12	7	;	;	PUNCT
admet-400	12	8	phospholipids	phospholipid	NOUN
admet-400	12	9	;	;	PUNCT
admet-400	12	10	antibiotics	antibiotic	NOUN
admet-400	12	11	introduction	introduction	NOUN
admet-400	12	12	pathogenic	pathogenic	ADJ
admet-400	12	13	bacteria	bacteria	NOUN
admet-400	12	14	pose	pose	VERB
admet-400	12	15	a	a	DET
admet-400	12	16	major	major	ADJ
admet-400	12	17	threaten	threaten	NOUN
admet-400	12	18	to	to	ADP
admet-400	12	19	public	public	ADJ
admet-400	12	20	health	health	NOUN
admet-400	12	21	,	,	PUNCT
admet-400	12	22	especially	especially	ADV
admet-400	12	23	in	in	ADP
admet-400	12	24	under	under	ADV
admet-400	12	25	-	-	PUNCT
admet-400	12	26	developed	develop	VERB
admet-400	12	27	region	region	NOUN
admet-400	12	28	of	of	ADP
admet-400	12	29	the	the	DET
admet-400	12	30	world	world	NOUN
admet-400	12	31	.	.	PUNCT
admet-400	13	1	large	large	ADJ
admet-400	13	2	scale	scale	NOUN
admet-400	13	3	production	production	NOUN
admet-400	13	4	and	and	CCONJ
admet-400	13	5	use	use	NOUN
admet-400	13	6	of	of	ADP
admet-400	13	7	antibiotic	antibiotic	ADJ
admet-400	13	8	penicillin	penicillin	NOUN
admet-400	13	9	during	during	ADP
admet-400	13	10	the	the	DET
admet-400	13	11	world	world	PROPN
admet-400	13	12	war	war	PROPN
admet-400	13	13	ii	ii	PROPN
admet-400	13	14	is	be	AUX
admet-400	13	15	a	a	DET
admet-400	13	16	hallmark	hallmark	NOUN
admet-400	13	17	of	of	ADP
admet-400	13	18	modern	modern	ADJ
admet-400	13	19	antimicrobial	antimicrobial	ADJ
admet-400	13	20	therapy	therapy	NOUN
admet-400	13	21	.	.	PUNCT
admet-400	14	1	since	since	SCONJ
admet-400	14	2	then	then	ADV
admet-400	14	3	,	,	PUNCT
admet-400	14	4	a	a	DET
admet-400	14	5	plethora	plethora	NOUN
admet-400	14	6	of	of	ADP
admet-400	14	7	antimicrobial	antimicrobial	ADJ
admet-400	14	8	agents	agent	NOUN
admet-400	14	9	have	have	AUX
admet-400	14	10	been	be	AUX
admet-400	14	11	developed	develop	VERB
admet-400	14	12	and	and	CCONJ
admet-400	14	13	commercialized	commercialize	VERB
admet-400	14	14	,	,	PUNCT
admet-400	14	15	playing	play	VERB
admet-400	14	16	significant	significant	ADJ
admet-400	14	17	roles	role	NOUN
admet-400	14	18	in	in	ADP
admet-400	14	19	improvement	improvement	NOUN
admet-400	14	20	of	of	ADP
admet-400	14	21	human	human	ADJ
admet-400	14	22	health	health	NOUN
admet-400	14	23	,	,	PUNCT
admet-400	14	24	highlighted	highlight	VERB
admet-400	14	25	by	by	ADP
admet-400	14	26	gradual	gradual	ADJ
admet-400	14	27	increasing	increasing	NOUN
admet-400	14	28	of	of	ADP
admet-400	14	29	average	average	ADJ
admet-400	14	30	life	life	NOUN
admet-400	14	31	span	span	VERB
admet-400	14	32	worldwide	worldwide	ADV
admet-400	14	33	.	.	PUNCT
admet-400	15	1	prevailing	prevail	VERB
admet-400	15	2	of	of	ADP
admet-400	15	3	antibiotic	antibiotic	ADJ
admet-400	15	4	treatment	treatment	NOUN
admet-400	15	5	improves	improve	VERB
admet-400	15	6	human	human	ADJ
admet-400	15	7	health	health	NOUN
admet-400	15	8	on	on	ADP
admet-400	15	9	one	one	NUM
admet-400	15	10	hand	hand	NOUN
admet-400	15	11	,	,	PUNCT
admet-400	15	12	but	but	CCONJ
admet-400	15	13	also	also	ADV
admet-400	15	14	triggers	trigger	VERB
admet-400	15	15	resistance	resistance	NOUN
admet-400	15	16	of	of	ADP
admet-400	15	17	microbes	microbe	NOUN
admet-400	15	18	to	to	ADP
admet-400	15	19	the	the	DET
admet-400	15	20	drugs	drug	NOUN
admet-400	15	21	[	[	X
admet-400	15	22	1,2	1,2	NUM
admet-400	15	23	]	]	PUNCT
admet-400	15	24	.	.	PUNCT
admet-400	16	1	depending	depend	VERB
admet-400	16	2	on	on	ADP
admet-400	16	3	their	their	PRON
admet-400	16	4	structures	structure	NOUN
admet-400	16	5	and	and	CCONJ
admet-400	16	6	target	target	VERB
admet-400	16	7	sites	site	NOUN
admet-400	16	8	within	within	ADP
admet-400	16	9	microorganism	microorganism	NOUN
admet-400	16	10	,	,	PUNCT
admet-400	16	11	different	different	ADJ
admet-400	16	12	antibacterial	antibacterial	ADJ
admet-400	16	13	drugs	drug	NOUN
admet-400	16	14	have	have	VERB
admet-400	16	15	distinct	distinct	ADJ
admet-400	16	16	modes	mode	NOUN
admet-400	16	17	of	of	ADP
admet-400	16	18	action	action	NOUN
admet-400	16	19	[	[	X
admet-400	16	20	3	3	NUM
admet-400	16	21	]	]	PUNCT
admet-400	16	22	.	.	PUNCT
admet-400	17	1	of	of	ADP
admet-400	17	2	them	they	PRON
admet-400	17	3	,	,	PUNCT
admet-400	17	4	related	relate	VERB
admet-400	17	5	to	to	ADP
admet-400	17	6	cell	cell	NOUN
admet-400	17	7	membrane	membrane	NOUN
admet-400	17	8	are	be	AUX
admet-400	17	9	:	:	PUNCT
admet-400	17	10	inhibition	inhibition	NOUN
admet-400	17	11	or	or	CCONJ
admet-400	17	12	block	block	NOUN
admet-400	17	13	of	of	ADP
admet-400	17	14	cell	cell	NOUN
admet-400	17	15	wall	wall	NOUN
admet-400	17	16	synthesis	synthesis	NOUN
admet-400	17	17	,	,	PUNCT
admet-400	17	18	inhibition	inhibition	NOUN
admet-400	17	19	of	of	ADP
admet-400	17	20	membrane	membrane	NOUN
admet-400	17	21	protein	protein	NOUN
admet-400	17	22	or	or	CCONJ
admet-400	17	23	lipid	lipid	ADJ
admet-400	17	24	synthesis	synthesis	NOUN
admet-400	17	25	and	and	CCONJ
admet-400	17	26	interference	interference	NOUN
admet-400	17	27	of	of	ADP
admet-400	17	28	cell	cell	NOUN
admet-400	17	29	membrane	membrane	NOUN
admet-400	17	30	function	function	NOUN
admet-400	17	31	.	.	PUNCT
admet-400	18	1	some	some	DET
admet-400	18	2	antibacterial	antibacterial	ADJ
admet-400	18	3	peptides	peptide	NOUN
admet-400	18	4	[	[	X
admet-400	18	5	4,5	4,5	NUM
admet-400	18	6	]	]	PUNCT
admet-400	18	7	,	,	PUNCT
admet-400	18	8	peptidomimics	peptidomimic	NOUN
admet-400	18	9	[	[	X
admet-400	18	10	6	6	NUM
admet-400	18	11	]	]	PUNCT
admet-400	18	12	and	and	CCONJ
admet-400	18	13	small	small	ADJ
admet-400	18	14	proteins	protein	NOUN
admet-400	18	15	[	[	X
admet-400	18	16	7	7	NUM
admet-400	18	17	]	]	PUNCT
admet-400	18	18	could	could	AUX
admet-400	18	19	interact	interact	VERB
admet-400	18	20	with	with	ADP
admet-400	18	21	or	or	CCONJ
admet-400	18	22	insert	insert	VERB
admet-400	18	23	into	into	ADP
admet-400	18	24	cell	cell	NOUN
admet-400	18	25	membrane	membrane	NOUN
admet-400	18	26	,	,	PUNCT
admet-400	18	27	where	where	SCONJ
admet-400	18	28	they	they	PRON
admet-400	18	29	interfere	interfere	VERB
admet-400	18	30	membrane	membrane	NOUN
admet-400	18	31	formation	formation	NOUN
admet-400	18	32	or	or	CCONJ
admet-400	18	33	alter	alter	VERB
admet-400	18	34	local	local	ADJ
admet-400	18	35	membrane	membrane	NOUN
admet-400	18	36	structure	structure	NOUN
admet-400	18	37	,	,	PUNCT
admet-400	18	38	thus	thus	ADV
admet-400	18	39	reducing	reduce	VERB
admet-400	18	40	bacteria	bacteria	NOUN
admet-400	18	41	growth	growth	NOUN
admet-400	18	42	or	or	CCONJ
admet-400	18	43	reproduction	reproduction	NOUN
admet-400	18	44	.	.	PUNCT
admet-400	19	1	bacterial	bacterial	ADJ
admet-400	19	2	membrane	membrane	NOUN
admet-400	19	3	is	be	AUX
admet-400	19	4	surrounded	surround	VERB
admet-400	19	5	by	by	ADP
admet-400	19	6	a	a	DET
admet-400	19	7	layer	layer	NOUN
admet-400	19	8	of	of	ADP
admet-400	19	9	peptidoglycan	peptidoglycan	ADJ
admet-400	19	10	cell	cell	NOUN
admet-400	19	11	wall	wall	NOUN
admet-400	19	12	.	.	PUNCT
admet-400	20	1	this	this	DET
admet-400	20	2	unique	unique	ADJ
admet-400	20	3	feature	feature	NOUN
admet-400	20	4	had	have	AUX
admet-400	20	5	rendered	render	VERB
admet-400	20	6	great	great	ADJ
admet-400	20	7	interest	interest	NOUN
admet-400	20	8	in	in	ADP
admet-400	20	9	searching	search	VERB
admet-400	20	10	for	for	ADP
admet-400	20	11	glycopeptide	glycopeptide	NOUN
admet-400	20	12	and	and	CCONJ
admet-400	20	13	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-400	20	14	mailto:kintam@umac.mo	mailto:kintam@umac.mo	PROPN
admet-400	20	15	hu	hu	PROPN
admet-400	20	16	and	and	CCONJ
admet-400	20	17	tam	tam	PROPN
admet-400	20	18	admet	admet	PROPN
admet-400	20	19	&	&	CCONJ
admet-400	20	20	dmpk	dmpk	PROPN
admet-400	20	21	5(3	5(3	NUM
admet-400	20	22	)	)	PUNCT
admet-400	20	23	(	(	PUNCT
admet-400	20	24	2017	2017	NUM
admet-400	20	25	)	)	PUNCT
admet-400	20	26	183	183	NUM
admet-400	20	27	-	-	SYM
admet-400	20	28	191	191	NUM
admet-400	20	29	184	184	NUM
admet-400	20	30	lipoglycopeptide	lipoglycopeptide	NOUN
admet-400	20	31	[	[	X
admet-400	20	32	8	8	NUM
admet-400	20	33	]	]	PUNCT
admet-400	20	34	,	,	PUNCT
admet-400	20	35	which	which	PRON
admet-400	20	36	mimics	mimic	VERB
admet-400	20	37	bacterial	bacterial	ADJ
admet-400	20	38	cell	cell	NOUN
admet-400	20	39	wall	wall	NOUN
admet-400	20	40	synthesis	synthesis	NOUN
admet-400	20	41	substrates	substrate	NOUN
admet-400	20	42	or	or	CCONJ
admet-400	20	43	binds	bind	VERB
admet-400	20	44	to	to	PART
admet-400	20	45	synthesis	synthesis	NOUN
admet-400	20	46	intermediates	intermediate	NOUN
admet-400	20	47	,	,	PUNCT
admet-400	20	48	thus	thus	ADV
admet-400	20	49	inhibits	inhibit	VERB
admet-400	20	50	cell	cell	NOUN
admet-400	20	51	wall	wall	NOUN
admet-400	20	52	synthesis	synthesis	PROPN
admet-400	20	53	,	,	PUNCT
admet-400	20	54	while	while	SCONJ
admet-400	20	55	having	have	VERB
admet-400	20	56	little	little	ADJ
admet-400	20	57	effect	effect	NOUN
admet-400	20	58	on	on	ADP
admet-400	20	59	host	host	NOUN
admet-400	20	60	cells	cell	NOUN
admet-400	20	61	.	.	PUNCT
admet-400	21	1	glycopeptide	glycopeptide	VERB
admet-400	21	2	antibiotic	antibiotic	ADJ
admet-400	21	3	vancomycin	vancomycin	PROPN
admet-400	21	4	has	have	AUX
admet-400	21	5	been	be	AUX
admet-400	21	6	used	use	VERB
admet-400	21	7	to	to	PART
admet-400	21	8	treat	treat	VERB
admet-400	21	9	a	a	DET
admet-400	21	10	number	number	NOUN
admet-400	21	11	of	of	ADP
admet-400	21	12	infections	infection	NOUN
admet-400	21	13	caused	cause	VERB
admet-400	21	14	by	by	ADP
admet-400	21	15	broad	broad	ADJ
admet-400	21	16	spectrum	spectrum	NOUN
admet-400	21	17	of	of	ADP
admet-400	21	18	gram	gram	NOUN
admet-400	21	19	-	-	PUNCT
admet-400	21	20	positive	positive	ADJ
admet-400	21	21	bacteria	bacteria	NOUN
admet-400	22	1	[	[	X
admet-400	22	2	9,10	9,10	NUM
admet-400	22	3	]	]	PUNCT
admet-400	22	4	.	.	PUNCT
admet-400	23	1	it	it	PRON
admet-400	23	2	inhibits	inhibit	VERB
admet-400	23	3	cell	cell	NOUN
admet-400	23	4	wall	wall	NOUN
admet-400	23	5	formation	formation	NOUN
admet-400	23	6	by	by	ADP
admet-400	23	7	binding	bind	VERB
admet-400	23	8	to	to	ADP
admet-400	23	9	d	d	PROPN
admet-400	23	10	-	-	PUNCT
admet-400	23	11	ala	ala	VERB
admet-400	23	12	-	-	PUNCT
admet-400	23	13	d	d	NOUN
admet-400	23	14	-	-	PUNCT
admet-400	23	15	ala	ala	ADJ
admet-400	23	16	terminus	terminus	NOUN
admet-400	23	17	of	of	ADP
admet-400	23	18	peptidoglycan	peptidoglycan	ADJ
admet-400	23	19	precursors	precursor	NOUN
admet-400	23	20	and	and	CCONJ
admet-400	23	21	preventing	prevent	VERB
admet-400	23	22	them	they	PRON
admet-400	23	23	from	from	ADP
admet-400	23	24	cross	cross	ADJ
admet-400	23	25	-	-	ADJ
admet-400	23	26	linking	link	VERB
admet-400	23	27	[	[	X
admet-400	23	28	11,12	11,12	NOUN
admet-400	23	29	]	]	PUNCT
admet-400	23	30	.	.	PUNCT
admet-400	24	1	to	to	PART
admet-400	24	2	cope	cope	VERB
admet-400	24	3	with	with	ADP
admet-400	24	4	rising	rise	VERB
admet-400	24	5	of	of	ADP
admet-400	24	6	antibiotic	antibiotic	ADJ
admet-400	24	7	resistance	resistance	NOUN
admet-400	24	8	including	include	VERB
admet-400	24	9	vancomycin	vancomycin	PROPN
admet-400	24	10	,	,	PUNCT
admet-400	24	11	development	development	NOUN
admet-400	24	12	of	of	ADP
admet-400	24	13	novel	novel	ADJ
admet-400	24	14	anti	anti	ADJ
admet-400	24	15	-	-	ADJ
admet-400	24	16	bacterial	bacterial	ADJ
admet-400	24	17	agents	agent	NOUN
admet-400	24	18	with	with	ADP
admet-400	24	19	multiple	multiple	ADJ
admet-400	24	20	action	action	NOUN
admet-400	24	21	modes	mode	NOUN
admet-400	24	22	had	have	AUX
admet-400	24	23	been	be	AUX
admet-400	24	24	a	a	DET
admet-400	24	25	promising	promising	ADJ
admet-400	24	26	strategy	strategy	NOUN
admet-400	24	27	[	[	X
admet-400	24	28	13–15	13–15	NUM
admet-400	24	29	]	]	PUNCT
admet-400	24	30	.	.	PUNCT
admet-400	25	1	herein	herein	NOUN
admet-400	25	2	,	,	PUNCT
admet-400	25	3	we	we	PRON
admet-400	25	4	studied	study	VERB
admet-400	25	5	the	the	DET
admet-400	25	6	binding	bind	VERB
admet-400	25	7	property	property	NOUN
admet-400	25	8	of	of	ADP
admet-400	25	9	vancomycin	vancomycin	PROPN
admet-400	25	10	to	to	ADP
admet-400	25	11	artificial	artificial	ADJ
admet-400	25	12	and	and	CCONJ
admet-400	25	13	bacterial	bacterial	ADJ
admet-400	25	14	membranes	membrane	NOUN
admet-400	25	15	using	use	VERB
admet-400	25	16	different	different	ADJ
admet-400	25	17	biophysics	biophysic	NOUN
admet-400	25	18	methods	method	NOUN
admet-400	25	19	with	with	ADP
admet-400	25	20	the	the	DET
admet-400	25	21	aim	aim	NOUN
admet-400	25	22	to	to	PART
admet-400	25	23	obtain	obtain	VERB
admet-400	25	24	a	a	DET
admet-400	25	25	better	well	ADJ
admet-400	25	26	understanding	understanding	NOUN
admet-400	25	27	of	of	ADP
admet-400	25	28	the	the	DET
admet-400	25	29	binding	bind	VERB
admet-400	25	30	process	process	NOUN
admet-400	25	31	for	for	ADP
admet-400	25	32	expanding	expand	VERB
admet-400	25	33	its	its	PRON
admet-400	25	34	antibiotic	antibiotic	ADJ
admet-400	25	35	repository	repository	NOUN
admet-400	25	36	.	.	PUNCT
admet-400	26	1	experimental	experimental	ADJ
admet-400	26	2	materials	material	NOUN
admet-400	26	3	1	1	NUM
admet-400	26	4	-	-	PUNCT
admet-400	26	5	palmitoyl-2	palmitoyl-2	VERB
admet-400	26	6	-	-	PUNCT
admet-400	26	7	oleoyl	oleoyl	NOUN
admet-400	26	8	-	-	PUNCT
admet-400	26	9	sn	sn	NOUN
admet-400	26	10	-	-	PUNCT
admet-400	26	11	glycero-3	glycero-3	NOUN
admet-400	26	12	-	-	PUNCT
admet-400	26	13	phospho-(1'-rac	phospho-(1'-rac	NOUN
admet-400	26	14	-	-	PUNCT
admet-400	26	15	glycerol	glycerol	NOUN
admet-400	26	16	)	)	PUNCT
admet-400	26	17	(	(	PUNCT
admet-400	26	18	sodium	sodium	NOUN
admet-400	26	19	salt	salt	NOUN
admet-400	26	20	)	)	PUNCT
admet-400	26	21	(	(	PUNCT
admet-400	26	22	popg	popg	NOUN
admet-400	26	23	)	)	PUNCT
admet-400	26	24	,	,	PUNCT
admet-400	26	25	1	1	NUM
admet-400	26	26	-	-	PUNCT
admet-400	26	27	hexadecanoyl-2-(9zoctadecenoyl)-sn	hexadecanoyl-2-(9zoctadecenoyl)-sn	VERB
admet-400	26	28	-	-	PUNCT
admet-400	26	29	glycero-3	glycero-3	NOUN
admet-400	26	30	-	-	PUNCT
admet-400	26	31	phosphoethanolamine	phosphoethanolamine	NOUN
admet-400	26	32	(	(	PUNCT
admet-400	26	33	pope	pope	NOUN
admet-400	26	34	)	)	PUNCT
admet-400	26	35	,	,	PUNCT
admet-400	26	36	1	1	NUM
admet-400	26	37	-	-	PUNCT
admet-400	26	38	oleoyl-2-[12-[(7	oleoyl-2-[12-[(7	NOUN
admet-400	26	39	-	-	PUNCT
admet-400	26	40	nitro-2	nitro-2	NUM
admet-400	26	41	-	-	PUNCT
admet-400	26	42	1,3	1,3	NUM
admet-400	26	43	-	-	PUNCT
admet-400	26	44	benzoxadiazol-4yl)amino]dodecanoyl]-sn	benzoxadiazol-4yl)amino]dodecanoyl]-sn	NOUN
admet-400	26	45	-	-	PUNCT
admet-400	26	46	glycero-3	glycero-3	NOUN
admet-400	26	47	-	-	PUNCT
admet-400	26	48	phosphocholine	phosphocholine	NOUN
admet-400	26	49	(	(	PUNCT
admet-400	26	50	nbd	nbd	PROPN
admet-400	26	51	pc	pc	PROPN
admet-400	26	52	)	)	PUNCT
admet-400	26	53	and	and	CCONJ
admet-400	26	54	cardiolipin	cardiolipin	NOUN
admet-400	26	55	(	(	PUNCT
admet-400	26	56	cl	cl	NOUN
admet-400	26	57	)	)	PUNCT
admet-400	26	58	were	be	AUX
admet-400	26	59	purchased	purchase	VERB
admet-400	26	60	from	from	ADP
admet-400	26	61	avanti	avanti	PROPN
admet-400	26	62	polar	polar	ADJ
admet-400	26	63	lipids	lipid	NOUN
admet-400	26	64	.	.	PUNCT
admet-400	27	1	vancomycin	vancomycin	PROPN
admet-400	27	2	and	and	CCONJ
admet-400	27	3	nafcillin	nafcillin	PROPN
admet-400	27	4	were	be	AUX
admet-400	27	5	obtained	obtain	VERB
admet-400	27	6	from	from	ADP
admet-400	27	7	sigma	sigma	PROPN
admet-400	27	8	.	.	PUNCT
admet-400	28	1	lysozyme	lysozyme	NOUN
admet-400	28	2	and	and	CCONJ
admet-400	28	3	rnasea	rnasea	NOUN
admet-400	28	4	were	be	AUX
admet-400	28	5	purchased	purchase	VERB
admet-400	28	6	from	from	ADP
admet-400	28	7	merck	merck	PROPN
admet-400	28	8	.	.	PROPN
admet-400	29	1	staphylococcus	staphylococcus	PROPN
admet-400	29	2	aureus	aureus	PROPN
admet-400	29	3	was	be	AUX
admet-400	29	4	from	from	ADP
admet-400	29	5	atcc	atcc	ADJ
admet-400	29	6	(	(	PUNCT
admet-400	29	7	strain	strain	VERB
admet-400	29	8	#	#	SYM
admet-400	29	9	43300	43300	NUM
admet-400	29	10	)	)	PUNCT
admet-400	29	11	and	and	CCONJ
admet-400	29	12	cultured	cultured	ADJ
admet-400	29	13	in	in	ADP
admet-400	29	14	tryptic	tryptic	ADJ
admet-400	29	15	soy	soy	NOUN
admet-400	29	16	broth	broth	NOUN
admet-400	29	17	medium	medium	NOUN
admet-400	29	18	(	(	PUNCT
admet-400	29	19	becton	becton	PROPN
admet-400	29	20	,	,	PUNCT
admet-400	29	21	dickinson	dickinson	NOUN
admet-400	29	22	and	and	CCONJ
admet-400	29	23	company	company	NOUN
admet-400	29	24	)	)	PUNCT
admet-400	29	25	.	.	PUNCT
admet-400	30	1	other	other	ADJ
admet-400	30	2	chemicals	chemical	NOUN
admet-400	30	3	were	be	AUX
admet-400	30	4	obtained	obtain	VERB
admet-400	30	5	from	from	ADP
admet-400	30	6	sigma	sigma	PROPN
admet-400	30	7	.	.	PUNCT
admet-400	31	1	liposome	liposome	VERB
admet-400	31	2	preparation	preparation	NOUN
admet-400	31	3	lipids	lipid	NOUN
admet-400	31	4	of	of	ADP
admet-400	31	5	known	know	VERB
admet-400	31	6	mass	mass	NOUN
admet-400	31	7	in	in	ADP
admet-400	31	8	chloroform	chloroform	NOUN
admet-400	31	9	were	be	AUX
admet-400	31	10	well	well	ADV
admet-400	31	11	-	-	PUNCT
admet-400	31	12	mixed	mix	VERB
admet-400	31	13	,	,	PUNCT
admet-400	31	14	then	then	ADV
admet-400	31	15	dried	dry	VERB
admet-400	31	16	at	at	ADP
admet-400	31	17	room	room	NOUN
admet-400	31	18	temperature	temperature	NOUN
admet-400	31	19	in	in	ADP
admet-400	31	20	a	a	DET
admet-400	31	21	glass	glass	NOUN
admet-400	31	22	tube	tube	NOUN
admet-400	31	23	by	by	ADP
admet-400	31	24	continuous	continuous	ADJ
admet-400	31	25	purging	purging	NOUN
admet-400	31	26	of	of	ADP
admet-400	31	27	high	high	ADJ
admet-400	31	28	pure	pure	ADJ
admet-400	31	29	nitrogen	nitrogen	NOUN
admet-400	31	30	gas	gas	NOUN
admet-400	31	31	.	.	PUNCT
admet-400	32	1	being	be	AUX
admet-400	32	2	thoroughly	thoroughly	ADV
admet-400	32	3	dried	dry	VERB
admet-400	32	4	in	in	ADP
admet-400	32	5	a	a	DET
admet-400	32	6	speed	speed	NOUN
admet-400	32	7	vacuum	vacuum	NOUN
admet-400	32	8	,	,	PUNCT
admet-400	32	9	the	the	DET
admet-400	32	10	lipids	lipid	NOUN
admet-400	32	11	were	be	AUX
admet-400	32	12	redissolved	redissolve	VERB
admet-400	32	13	in	in	ADP
admet-400	32	14	phosphate	phosphate	ADJ
admet-400	32	15	buffer	buffer	NOUN
admet-400	32	16	saline	saline	NOUN
admet-400	32	17	(	(	PUNCT
admet-400	32	18	pbs	pbs	NOUN
admet-400	32	19	)	)	PUNCT
admet-400	32	20	buffer	buffer	NOUN
admet-400	32	21	(	(	PUNCT
admet-400	32	22	10	10	NUM
admet-400	32	23	mm	mm	PROPN
admet-400	32	24	na2hpo4	na2hpo4	PROPN
admet-400	32	25	,	,	PUNCT
admet-400	32	26	1.8	1.8	NUM
admet-400	32	27	mm	mm	PROPN
admet-400	32	28	kh2po4	kh2po4	NOUN
admet-400	32	29	,	,	PUNCT
admet-400	32	30	137	137	NUM
admet-400	32	31	mm	mm	NOUN
admet-400	32	32	nacl	nacl	NOUN
admet-400	32	33	,	,	PUNCT
admet-400	32	34	2.7	2.7	NUM
admet-400	32	35	mm	mm	NOUN
admet-400	32	36	kcl	kcl	PROPN
admet-400	32	37	,	,	PUNCT
admet-400	32	38	ph	ph	NOUN
admet-400	32	39	7.4	7.4	NUM
admet-400	32	40	)	)	PUNCT
admet-400	32	41	pre	pre	VERB
admet-400	32	42	-	-	VERB
admet-400	32	43	warmed	warm	VERB
admet-400	32	44	over	over	ADP
admet-400	32	45	45	45	NUM
admet-400	32	46	°	°	NOUN
admet-400	32	47	c	c	NOUN
admet-400	32	48	.	.	PUNCT
admet-400	33	1	after	after	ADP
admet-400	33	2	repeated	repeat	VERB
admet-400	33	3	pipetting	pipetting	NOUN
admet-400	33	4	,	,	PUNCT
admet-400	33	5	the	the	DET
admet-400	33	6	hydrated	hydrated	ADJ
admet-400	33	7	lipids	lipid	NOUN
admet-400	33	8	were	be	AUX
admet-400	33	9	applied	apply	VERB
admet-400	33	10	to	to	ADP
admet-400	33	11	a	a	DET
admet-400	33	12	lipex	lipex	NOUN
admet-400	33	13	extruder	extruder	NOUN
admet-400	33	14	(	(	PUNCT
admet-400	33	15	northern	northern	PROPN
admet-400	33	16	lipids	lipids	PROPN
admet-400	33	17	inc	inc	PROPN
admet-400	33	18	.	.	PROPN
admet-400	33	19	)	)	PUNCT
admet-400	33	20	equipped	equip	VERB
admet-400	33	21	with	with	ADP
admet-400	33	22	polycarbonate	polycarbonate	ADJ
admet-400	33	23	membrane	membrane	NOUN
admet-400	33	24	for	for	ADP
admet-400	33	25	more	more	ADJ
admet-400	33	26	than	than	ADP
admet-400	33	27	10	10	NUM
admet-400	33	28	times	time	NOUN
admet-400	33	29	.	.	PUNCT
admet-400	34	1	scattering	scatter	VERB
admet-400	34	2	profile	profile	NOUN
admet-400	34	3	of	of	ADP
admet-400	34	4	the	the	DET
admet-400	34	5	liposome	liposome	NOUN
admet-400	34	6	was	be	AUX
admet-400	34	7	then	then	ADV
admet-400	34	8	measured	measure	VERB
admet-400	34	9	on	on	ADP
admet-400	34	10	a	a	DET
admet-400	34	11	bi-200sm	bi-200sm	X
admet-400	34	12	goniometer	goniometer	NOUN
admet-400	34	13	(	(	PUNCT
admet-400	34	14	brookhaven	brookhaven	NOUN
admet-400	34	15	instruments	instrument	NOUN
admet-400	34	16	)	)	PUNCT
admet-400	34	17	while	while	SCONJ
admet-400	34	18	being	be	AUX
admet-400	34	19	excited	excite	VERB
admet-400	34	20	by	by	ADP
admet-400	34	21	a	a	DET
admet-400	34	22	laser	laser	NOUN
admet-400	34	23	passing	pass	VERB
admet-400	34	24	637	637	NUM
admet-400	34	25	nm	nm	ADJ
admet-400	34	26	filter	filter	NOUN
admet-400	34	27	with	with	ADP
admet-400	34	28	100	100	NUM
admet-400	34	29	micron	micron	NOUN
admet-400	34	30	pinhole	pinhole	NOUN
admet-400	34	31	from	from	ADP
admet-400	34	32	90	90	NUM
admet-400	34	33	degree	degree	NOUN
admet-400	34	34	angle	angle	NOUN
admet-400	34	35	at	at	ADP
admet-400	34	36	25	25	NUM
admet-400	34	37	°	°	NOUN
admet-400	34	38	c	c	NOUN
admet-400	34	39	.	.	PUNCT
admet-400	35	1	data	datum	NOUN
admet-400	35	2	was	be	AUX
admet-400	35	3	collected	collect	VERB
admet-400	35	4	and	and	CCONJ
admet-400	35	5	processed	process	VERB
admet-400	35	6	by	by	ADP
admet-400	35	7	the	the	DET
admet-400	35	8	dynamic	dynamic	ADJ
admet-400	35	9	light	light	NOUN
admet-400	35	10	scatter	scatter	NOUN
admet-400	35	11	software	software	NOUN
admet-400	35	12	coming	come	VERB
admet-400	35	13	with	with	ADP
admet-400	35	14	the	the	DET
admet-400	35	15	equipment	equipment	NOUN
admet-400	35	16	.	.	PUNCT
admet-400	36	1	isolation	isolation	NOUN
admet-400	36	2	of	of	ADP
admet-400	36	3	membrane	membrane	NOUN
admet-400	36	4	from	from	ADP
admet-400	36	5	staphylococcus	staphylococcus	NOUN
admet-400	36	6	aureus	aureus	NOUN
admet-400	36	7	isolation	isolation	NOUN
admet-400	36	8	of	of	ADP
admet-400	36	9	membrane	membrane	NOUN
admet-400	36	10	was	be	AUX
admet-400	36	11	carried	carry	VERB
admet-400	36	12	out	out	ADP
admet-400	36	13	as	as	SCONJ
admet-400	36	14	described	describe	VERB
admet-400	36	15	in	in	ADP
admet-400	36	16	the	the	DET
admet-400	36	17	literature	literature	NOUN
admet-400	37	1	[	[	X
admet-400	37	2	16	16	NUM
admet-400	37	3	]	]	PUNCT
admet-400	37	4	.	.	PUNCT
admet-400	38	1	briefly	briefly	NOUN
admet-400	38	2	,	,	PUNCT
admet-400	38	3	bacteria	bacteria	NOUN
admet-400	38	4	were	be	AUX
admet-400	38	5	cultured	cultured	ADJ
admet-400	38	6	till	till	SCONJ
admet-400	38	7	late	late	ADJ
admet-400	38	8	exponential	exponential	ADJ
admet-400	38	9	phase	phase	NOUN
admet-400	38	10	before	before	ADP
admet-400	38	11	harvest	harvest	NOUN
admet-400	38	12	.	.	PUNCT
admet-400	39	1	cells	cell	NOUN
admet-400	39	2	was	be	AUX
admet-400	39	3	then	then	ADV
admet-400	39	4	re	re	VERB
admet-400	39	5	-	-	VERB
admet-400	39	6	suspended	suspend	VERB
admet-400	39	7	in	in	ADP
admet-400	39	8	50	50	NUM
admet-400	39	9	mm	mm	NOUN
admet-400	39	10	potassium	potassium	NOUN
admet-400	39	11	phosphate	phosphate	NOUN
admet-400	39	12	buffer	buffer	NOUN
admet-400	39	13	,	,	PUNCT
admet-400	39	14	ph	ph	X
admet-400	39	15	8.0	8.0	NUM
admet-400	39	16	and	and	CCONJ
admet-400	39	17	digested	digest	VERB
admet-400	39	18	by	by	ADP
admet-400	39	19	lysozyme	lysozyme	NOUN
admet-400	39	20	,	,	PUNCT
admet-400	39	21	deoxyribonuclease-1	deoxyribonuclease-1	PROPN
admet-400	39	22	and	and	CCONJ
admet-400	39	23	ribonuclease	ribonuclease	NOUN
admet-400	39	24	for	for	ADP
admet-400	39	25	30	30	NUM
admet-400	39	26	minutes	minute	NOUN
admet-400	39	27	in	in	ADP
admet-400	39	28	the	the	DET
admet-400	39	29	presence	presence	NOUN
admet-400	39	30	of	of	ADP
admet-400	39	31	10	10	NUM
admet-400	39	32	mm	mm	NOUN
admet-400	39	33	mgso4	mgso4	NOUN
admet-400	39	34	at	at	ADP
admet-400	39	35	37	37	NUM
admet-400	39	36	°	°	NOUN
admet-400	39	37	c	c	NOUN
admet-400	39	38	.	.	PUNCT
admet-400	40	1	the	the	DET
admet-400	40	2	reaction	reaction	NOUN
admet-400	40	3	was	be	AUX
admet-400	40	4	stopped	stop	VERB
admet-400	40	5	abruptly	abruptly	ADV
admet-400	40	6	by	by	ADP
admet-400	40	7	15	15	NUM
admet-400	40	8	mm	mm	NOUN
admet-400	40	9	edta	edta	NOUN
admet-400	40	10	for	for	ADP
admet-400	40	11	1	1	NUM
admet-400	40	12	minute	minute	NOUN
admet-400	40	13	.	.	PUNCT
admet-400	41	1	additional	additional	ADJ
admet-400	41	2	mgso4	mgso4	PROPN
admet-400	41	3	was	be	AUX
admet-400	41	4	then	then	ADV
admet-400	41	5	added	add	VERB
admet-400	41	6	to	to	ADP
admet-400	41	7	the	the	DET
admet-400	41	8	system	system	NOUN
admet-400	41	9	to	to	PART
admet-400	41	10	bring	bring	VERB
admet-400	41	11	its	its	PRON
admet-400	41	12	final	final	ADJ
admet-400	41	13	concentration	concentration	NOUN
admet-400	41	14	back	back	ADV
admet-400	41	15	to	to	ADP
admet-400	41	16	10	10	NUM
admet-400	41	17	mm	mm	NOUN
admet-400	41	18	.	.	PUNCT
admet-400	42	1	digested	digested	PROPN
admet-400	42	2	cells	cell	NOUN
admet-400	42	3	was	be	AUX
admet-400	42	4	centrifuged	centrifuge	VERB
admet-400	42	5	at	at	ADP
admet-400	42	6	room	room	NOUN
admet-400	42	7	temperature	temperature	NOUN
admet-400	42	8	,	,	PUNCT
admet-400	42	9	25000	25000	NUM
admet-400	42	10	g	g	NOUN
admet-400	42	11	for	for	ADP
admet-400	42	12	45	45	NUM
admet-400	42	13	minutes	minute	NOUN
admet-400	42	14	to	to	PART
admet-400	42	15	pellet	pellet	VERB
admet-400	42	16	the	the	DET
admet-400	42	17	membrane	membrane	NOUN
admet-400	42	18	,	,	PUNCT
admet-400	42	19	which	which	PRON
admet-400	42	20	was	be	AUX
admet-400	42	21	then	then	ADV
admet-400	42	22	re	re	VERB
admet-400	42	23	-	-	VERB
admet-400	42	24	suspended	suspend	VERB
admet-400	42	25	in	in	ADP
admet-400	42	26	pbs	pbs	PROPN
admet-400	42	27	and	and	CCONJ
admet-400	42	28	applied	apply	VERB
admet-400	42	29	through	through	ADP
admet-400	42	30	18	18	NUM
admet-400	42	31	-	-	PUNCT
admet-400	42	32	g	g	NOUN
admet-400	42	33	needle	needle	NOUN
admet-400	42	34	for	for	ADP
admet-400	42	35	more	more	ADJ
admet-400	42	36	than	than	ADP
admet-400	42	37	20	20	NUM
admet-400	42	38	times	time	NOUN
admet-400	42	39	.	.	PUNCT
admet-400	43	1	resultant	resultant	VERB
admet-400	43	2	membrane	membrane	NOUN
admet-400	43	3	vesicle	vesicle	NOUN
admet-400	43	4	was	be	AUX
admet-400	43	5	quantified	quantify	VERB
admet-400	43	6	by	by	ADP
admet-400	43	7	measuring	measure	VERB
admet-400	43	8	protein	protein	NOUN
admet-400	43	9	concentration	concentration	NOUN
admet-400	43	10	(	(	PUNCT
admet-400	43	11	pierce	pierce	PROPN
admet-400	43	12	™	™	VERB
admet-400	43	13	bca	bca	PROPN
admet-400	43	14	protein	protein	NOUN
admet-400	43	15	assay	assay	VERB
admet-400	43	16	,	,	PUNCT
admet-400	43	17	thermo	thermo	NOUN
admet-400	43	18	scientific	scientific	NOUN
admet-400	43	19	)	)	PUNCT
admet-400	43	20	,	,	PUNCT
admet-400	43	21	assuming	assume	VERB
admet-400	43	22	equivalent	equivalent	ADJ
admet-400	43	23	amount	amount	NOUN
admet-400	43	24	of	of	ADP
admet-400	43	25	protein	protein	NOUN
admet-400	43	26	and	and	CCONJ
admet-400	43	27	lipid	lipid	NOUN
admet-400	43	28	.	.	PUNCT
admet-400	44	1	size	size	NOUN
admet-400	44	2	distribution	distribution	NOUN
admet-400	44	3	of	of	ADP
admet-400	44	4	the	the	DET
admet-400	44	5	vesicles	vesicle	NOUN
admet-400	44	6	was	be	AUX
admet-400	44	7	assessed	assess	VERB
admet-400	44	8	on	on	ADP
admet-400	44	9	a	a	DET
admet-400	44	10	bi200sm	bi200sm	NOUN
admet-400	44	11	goniometer	goniometer	NOUN
admet-400	44	12	as	as	ADP
admet-400	44	13	describe	describe	NOUN
admet-400	44	14	in	in	ADP
admet-400	44	15	previous	previous	ADJ
admet-400	44	16	section	section	NOUN
admet-400	44	17	.	.	PUNCT
admet-400	45	1	isothermal	isothermal	PROPN
admet-400	45	2	calorimetry	calorimetry	NOUN
admet-400	45	3	measurement	measurement	NOUN
admet-400	45	4	in	in	ADP
admet-400	45	5	a	a	DET
admet-400	45	6	typical	typical	ADJ
admet-400	45	7	isothermal	isothermal	ADJ
admet-400	45	8	calorimetry	calorimetry	NOUN
admet-400	45	9	(	(	PUNCT
admet-400	45	10	itc	itc	PROPN
admet-400	45	11	)	)	PUNCT
admet-400	45	12	experiment	experiment	NOUN
admet-400	45	13	carried	carry	VERB
admet-400	45	14	out	out	ADP
admet-400	45	15	on	on	ADP
admet-400	45	16	a	a	DET
admet-400	45	17	microcal	microcal	ADJ
admet-400	45	18	itc200	itc200	NOUN
admet-400	45	19	calorimeter	calorimeter	NOUN
admet-400	45	20	(	(	PUNCT
admet-400	45	21	malvern	malvern	PROPN
admet-400	45	22	instruments	instrument	NOUN
admet-400	45	23	)	)	PUNCT
admet-400	45	24	,	,	PUNCT
admet-400	45	25	50	50	NUM
admet-400	45	26	mm	mm	NOUN
admet-400	45	27	antibiotics	antibiotic	NOUN
admet-400	45	28	were	be	AUX
admet-400	45	29	titrated	titrate	VERB
admet-400	45	30	into	into	ADP
admet-400	45	31	liposome	liposome	NOUN
admet-400	45	32	with	with	ADP
admet-400	45	33	5	5	NUM
admet-400	45	34	mm	mm	NOUN
admet-400	45	35	lipid	lipid	NOUN
admet-400	45	36	(	(	PUNCT
admet-400	45	37	total	total	NOUN
admet-400	45	38	or	or	CCONJ
admet-400	45	39	individual	individual	ADJ
admet-400	45	40	)	)	PUNCT
admet-400	45	41	in	in	ADP
admet-400	45	42	pbs	pbs	PROPN
admet-400	45	43	buffer	buffer	NOUN
admet-400	45	44	at	at	ADP
admet-400	45	45	25	25	NUM
admet-400	45	46	°	°	NOUN
admet-400	45	47	c	c	NOUN
admet-400	45	48	.	.	PUNCT
admet-400	46	1	after	after	ADP
admet-400	46	2	each	each	DET
admet-400	46	3	injection	injection	NOUN
admet-400	46	4	,	,	PUNCT
admet-400	46	5	system	system	NOUN
admet-400	46	6	was	be	AUX
admet-400	46	7	allowed	allow	VERB
admet-400	46	8	to	to	PART
admet-400	46	9	regain	regain	VERB
admet-400	46	10	thermal	thermal	ADJ
admet-400	46	11	balance	balance	NOUN
admet-400	46	12	between	between	ADP
admet-400	46	13	sample	sample	NOUN
admet-400	46	14	admet	admet	PROPN
admet-400	46	15	&	&	CCONJ
admet-400	46	16	dmpk	dmpk	PROPN
admet-400	46	17	5(3	5(3	NUM
admet-400	46	18	)	)	PUNCT
admet-400	46	19	(	(	PUNCT
admet-400	46	20	2017	2017	NUM
admet-400	46	21	)	)	PUNCT
admet-400	46	22	183	183	NUM
admet-400	46	23	-	-	SYM
admet-400	46	24	191	191	NUM
admet-400	46	25	association	association	NOUN
admet-400	46	26	of	of	ADP
admet-400	46	27	vancomycin	vancomycin	PROPN
admet-400	46	28	with	with	ADP
admet-400	46	29	lipid	lipid	NOUN
admet-400	46	30	vesicles	vesicle	NOUN
admet-400	46	31	doi	doi	NOUN
admet-400	46	32	:	:	PUNCT
admet-400	46	33	10.5599	10.5599	NUM
admet-400	46	34	/	/	SYM
admet-400	46	35	admet.5.3.400	admet.5.3.400	PROPN
admet-400	46	36	185	185	NUM
admet-400	46	37	and	and	CCONJ
admet-400	46	38	reference	reference	NOUN
admet-400	46	39	chambers	chamber	NOUN
admet-400	46	40	for	for	ADP
admet-400	46	41	180	180	NUM
admet-400	46	42	seconds	second	NOUN
admet-400	46	43	with	with	ADP
admet-400	46	44	continuous	continuous	ADJ
admet-400	46	45	stir	stir	NOUN
admet-400	46	46	of	of	ADP
admet-400	46	47	750	750	NUM
admet-400	46	48	rpm	rpm	NOUN
admet-400	46	49	.	.	PUNCT
admet-400	47	1	acquired	acquire	VERB
admet-400	47	2	data	datum	NOUN
admet-400	47	3	were	be	AUX
admet-400	47	4	processed	process	VERB
admet-400	47	5	by	by	ADP
admet-400	47	6	itc	itc	PROPN
admet-400	47	7	-	-	PUNCT
admet-400	47	8	costumed	costume	VERB
admet-400	47	9	origin7	origin7	NOUN
admet-400	47	10	software	software	NOUN
admet-400	47	11	using	use	VERB
admet-400	47	12	one	one	NUM
admet-400	47	13	-	-	PUNCT
admet-400	47	14	site	site	NOUN
admet-400	47	15	model	model	NOUN
admet-400	47	16	to	to	PART
admet-400	47	17	avoid	avoid	VERB
admet-400	47	18	complication	complication	NOUN
admet-400	47	19	.	.	PUNCT
admet-400	48	1	reference	reference	NOUN
admet-400	48	2	subtractions	subtraction	NOUN
admet-400	48	3	were	be	AUX
admet-400	48	4	performed	perform	VERB
admet-400	48	5	against	against	ADP
admet-400	48	6	the	the	DET
admet-400	48	7	data	datum	NOUN
admet-400	48	8	obtained	obtain	VERB
admet-400	48	9	by	by	ADP
admet-400	48	10	titrating	titrate	VERB
admet-400	48	11	antibiotic	antibiotic	NOUN
admet-400	48	12	into	into	ADP
admet-400	48	13	pbs	pbs	PROPN
admet-400	48	14	buffer	buffer	NOUN
admet-400	48	15	.	.	PUNCT
admet-400	49	1	fluorescence	fluorescence	NOUN
admet-400	49	2	spectroscopy	spectroscopy	VERB
admet-400	49	3	spectra	spectra	NOUN
admet-400	49	4	of	of	ADP
admet-400	49	5	the	the	DET
admet-400	49	6	fluorescent	fluorescent	NOUN
admet-400	49	7	lipid	lipid	NOUN
admet-400	49	8	incorporated	incorporate	VERB
admet-400	49	9	liposome	liposome	NOUN
admet-400	49	10	were	be	AUX
admet-400	49	11	collected	collect	VERB
admet-400	49	12	on	on	ADP
admet-400	49	13	an	an	DET
admet-400	49	14	ls55	ls55	PROPN
admet-400	49	15	fluorescence	fluorescence	NOUN
admet-400	49	16	spectrometer	spectrometer	NOUN
admet-400	49	17	(	(	PUNCT
admet-400	49	18	perkinelmer	perkinelmer	NOUN
admet-400	49	19	)	)	PUNCT
admet-400	49	20	at	at	ADP
admet-400	49	21	room	room	NOUN
admet-400	49	22	temperature	temperature	NOUN
admet-400	49	23	.	.	PUNCT
admet-400	50	1	fluorescent	fluorescent	ADJ
admet-400	50	2	spectra	spectra	NOUN
admet-400	50	3	of	of	ADP
admet-400	50	4	freshly	freshly	ADV
admet-400	50	5	prepares	prepare	VERB
admet-400	50	6	2	2	NUM
admet-400	50	7	-	-	SYM
admet-400	50	8	4	4	NUM
admet-400	50	9	mm	mm	NOUN
admet-400	50	10	liposome	liposome	NOUN
admet-400	50	11	containing	contain	VERB
admet-400	50	12	0.5	0.5	NUM
admet-400	50	13	%	%	NOUN
admet-400	50	14	ndb	ndb	NOUN
admet-400	50	15	pc	pc	NOUN
admet-400	50	16	in	in	ADP
admet-400	50	17	pbs	pbs	PROPN
admet-400	50	18	buffer	buffer	NOUN
admet-400	50	19	was	be	AUX
admet-400	50	20	recorded	record	VERB
admet-400	50	21	in	in	ADP
admet-400	50	22	a	a	DET
admet-400	50	23	cuvette	cuvette	NOUN
admet-400	50	24	.	.	PUNCT
admet-400	51	1	the	the	DET
admet-400	51	2	sample	sample	NOUN
admet-400	51	3	was	be	AUX
admet-400	51	4	excited	excite	VERB
admet-400	51	5	by	by	ADP
admet-400	51	6	xenon	xenon	NOUN
admet-400	51	7	lamp	lamp	PROPN
admet-400	51	8	centred	centre	VERB
admet-400	51	9	at	at	ADP
admet-400	51	10	485	485	NUM
admet-400	51	11	nm	nm	NOUN
admet-400	51	12	with	with	ADP
admet-400	51	13	2.5	2.5	NUM
admet-400	51	14	nm	nm	ADV
admet-400	51	15	slit	slit	ADJ
admet-400	51	16	width	width	NOUN
admet-400	51	17	.	.	PUNCT
admet-400	52	1	a	a	DET
admet-400	52	2	fraction	fraction	NOUN
admet-400	52	3	of	of	ADP
admet-400	52	4	antibiotics	antibiotic	NOUN
admet-400	52	5	with	with	ADP
admet-400	52	6	high	high	ADJ
admet-400	52	7	concentration	concentration	NOUN
admet-400	52	8	in	in	ADP
admet-400	52	9	pbs	pbs	PROPN
admet-400	52	10	buffer	buffer	NOUN
admet-400	52	11	was	be	AUX
admet-400	52	12	then	then	ADV
admet-400	52	13	introduced	introduce	VERB
admet-400	52	14	to	to	PART
admet-400	52	15	minimize	minimize	VERB
admet-400	52	16	volume	volume	NOUN
admet-400	52	17	change	change	NOUN
admet-400	52	18	.	.	PUNCT
admet-400	53	1	after	after	ADP
admet-400	53	2	mixed	mixed	ADJ
admet-400	53	3	well	well	ADV
admet-400	53	4	,	,	PUNCT
admet-400	53	5	the	the	DET
admet-400	53	6	spectrum	spectrum	NOUN
admet-400	53	7	of	of	ADP
admet-400	53	8	the	the	DET
admet-400	53	9	sample	sample	NOUN
admet-400	53	10	was	be	AUX
admet-400	53	11	measured	measure	VERB
admet-400	53	12	with	with	ADP
admet-400	53	13	the	the	DET
admet-400	53	14	same	same	ADJ
admet-400	53	15	setting	setting	NOUN
admet-400	53	16	.	.	PUNCT
admet-400	54	1	results	result	NOUN
admet-400	54	2	vancomycin	vancomycin	PROPN
admet-400	54	3	binds	bind	VERB
admet-400	54	4	to	to	PART
admet-400	54	5	liposome	liposome	VERB
admet-400	54	6	with	with	ADP
admet-400	54	7	a	a	DET
admet-400	54	8	millimolar	millimolar	ADJ
admet-400	54	9	affinity	affinity	NOUN
admet-400	54	10	.	.	PUNCT
admet-400	55	1	we	we	PRON
admet-400	55	2	first	first	ADV
admet-400	55	3	utilized	utilize	VERB
admet-400	55	4	liposome	liposome	NOUN
admet-400	55	5	as	as	ADP
admet-400	55	6	membrane	membrane	NOUN
admet-400	55	7	mimic	mimic	NOUN
admet-400	55	8	to	to	PART
admet-400	55	9	explore	explore	VERB
admet-400	55	10	if	if	SCONJ
admet-400	55	11	vancomycin	vancomycin	PROPN
admet-400	55	12	associates	associate	NOUN
admet-400	55	13	with	with	ADP
admet-400	55	14	the	the	DET
admet-400	55	15	cell	cell	NOUN
admet-400	55	16	membrane	membrane	NOUN
admet-400	55	17	at	at	ADV
admet-400	55	18	all	all	ADV
admet-400	55	19	.	.	PUNCT
admet-400	56	1	we	we	PRON
admet-400	56	2	performed	perform	VERB
admet-400	56	3	isothermal	isothermal	ADJ
admet-400	56	4	calorimetry	calorimetry	NOUN
admet-400	56	5	experiment	experiment	NOUN
admet-400	56	6	by	by	ADP
admet-400	56	7	titrating	titrate	VERB
admet-400	56	8	antibiotics	antibiotic	NOUN
admet-400	56	9	into	into	ADP
admet-400	56	10	liposome	liposome	NOUN
admet-400	56	11	extruded	extrude	VERB
admet-400	56	12	through	through	ADP
admet-400	56	13	polycarbonate	polycarbonate	ADJ
admet-400	56	14	membrane	membrane	NOUN
admet-400	56	15	(	(	PUNCT
admet-400	56	16	0.1	0.1	NUM
admet-400	56	17	µm	µm	ADP
admet-400	56	18	diameter	diameter	NOUN
admet-400	56	19	)	)	PUNCT
admet-400	56	20	.	.	PUNCT
admet-400	57	1	we	we	PRON
admet-400	57	2	found	find	VERB
admet-400	57	3	that	that	SCONJ
admet-400	57	4	vancomycin	vancomycin	PROPN
admet-400	57	5	,	,	PUNCT
admet-400	57	6	but	but	CCONJ
admet-400	57	7	not	not	PART
admet-400	57	8	βlactam	βlactam	VERB
admet-400	57	9	antibiotic	antibiotic	ADJ
admet-400	57	10	nafcillin	nafcillin	NOUN
admet-400	57	11	,	,	PUNCT
admet-400	57	12	introduced	introduce	VERB
admet-400	57	13	significant	significant	ADJ
admet-400	57	14	amount	amount	NOUN
admet-400	57	15	of	of	ADP
admet-400	57	16	heat	heat	NOUN
admet-400	57	17	change	change	NOUN
admet-400	57	18	in	in	ADP
admet-400	57	19	liposome	liposome	NOUN
admet-400	57	20	prepared	prepare	VERB
admet-400	57	21	from	from	ADP
admet-400	57	22	a	a	DET
admet-400	57	23	mixture	mixture	NOUN
admet-400	57	24	of	of	ADP
admet-400	57	25	pope	pope	NOUN
admet-400	57	26	,	,	PUNCT
admet-400	57	27	popg	popg	ADJ
admet-400	57	28	and	and	CCONJ
admet-400	57	29	cardiolipin	cardiolipin	NOUN
admet-400	57	30	(	(	PUNCT
admet-400	57	31	cl	cl	NOUN
admet-400	57	32	)	)	PUNCT
admet-400	57	33	(	(	PUNCT
admet-400	57	34	75:20:5	75:20:5	NUM
admet-400	57	35	)	)	PUNCT
admet-400	57	36	(	(	PUNCT
admet-400	57	37	figure	figure	NOUN
admet-400	57	38	1	1	NUM
admet-400	57	39	)	)	PUNCT
admet-400	57	40	,	,	PUNCT
admet-400	57	41	a	a	DET
admet-400	57	42	model	model	NOUN
admet-400	57	43	mimic	mimic	NOUN
admet-400	57	44	for	for	ADP
admet-400	57	45	bacterial	bacterial	ADJ
admet-400	57	46	membrane	membrane	NOUN
admet-400	57	47	[	[	X
admet-400	57	48	17	17	NUM
admet-400	57	49	]	]	PUNCT
admet-400	57	50	.	.	PUNCT
admet-400	58	1	fitting	fit	VERB
admet-400	58	2	of	of	ADP
admet-400	58	3	the	the	DET
admet-400	58	4	data	datum	NOUN
admet-400	58	5	into	into	ADP
admet-400	58	6	one	one	NUM
admet-400	58	7	-	-	PUNCT
admet-400	58	8	site	site	NOUN
admet-400	58	9	model	model	NOUN
admet-400	58	10	gave	give	VERB
admet-400	58	11	rise	rise	NOUN
admet-400	58	12	to	to	ADP
admet-400	58	13	millimolar	millimolar	ADJ
admet-400	58	14	level	level	NOUN
admet-400	58	15	affinity	affinity	NOUN
admet-400	58	16	(	(	PUNCT
admet-400	58	17	dissociate	dissociate	NOUN
admet-400	58	18	constant	constant	ADJ
admet-400	58	19	,	,	PUNCT
admet-400	58	20	kd	kd	PROPN
admet-400	58	21	)	)	PUNCT
admet-400	58	22	,	,	PUNCT
admet-400	58	23	suggesting	suggest	VERB
admet-400	58	24	that	that	SCONJ
admet-400	58	25	vancomycin	vancomycin	PROPN
admet-400	58	26	weakly	weakly	ADV
admet-400	58	27	,	,	PUNCT
admet-400	58	28	but	but	CCONJ
admet-400	58	29	definitely	definitely	ADV
admet-400	58	30	interact	interact	VERB
admet-400	58	31	with	with	ADP
admet-400	58	32	liposome	liposome	NOUN
admet-400	58	33	.	.	PUNCT
admet-400	59	1	the	the	DET
admet-400	59	2	observation	observation	NOUN
admet-400	59	3	is	be	AUX
admet-400	59	4	in	in	ADP
admet-400	59	5	line	line	NOUN
admet-400	59	6	with	with	ADP
admet-400	59	7	previous	previous	ADJ
admet-400	59	8	studies	study	NOUN
admet-400	59	9	,	,	PUNCT
admet-400	59	10	where	where	SCONJ
admet-400	59	11	weak	weak	ADJ
admet-400	59	12	binding	binding	NOUN
admet-400	59	13	of	of	ADP
admet-400	59	14	vancomycin	vancomycin	PROPN
admet-400	59	15	to	to	PART
admet-400	59	16	model	model	VERB
admet-400	59	17	membrane	membrane	NOUN
admet-400	59	18	were	be	AUX
admet-400	59	19	assessed	assess	VERB
admet-400	59	20	by	by	ADP
admet-400	59	21	itc	itc	PROPN
admet-400	59	22	[	[	X
admet-400	59	23	18	18	NUM
admet-400	59	24	]	]	PUNCT
admet-400	59	25	and	and	CCONJ
admet-400	59	26	surface	surface	NOUN
admet-400	59	27	plasmon	plasmon	ADJ
admet-400	59	28	resonance	resonance	NOUN
admet-400	59	29	[	[	X
admet-400	59	30	19	19	NUM
admet-400	59	31	]	]	PUNCT
admet-400	59	32	.	.	PUNCT
admet-400	60	1	figure	figure	NOUN
admet-400	60	2	1	1	NUM
admet-400	60	3	.	.	PUNCT
admet-400	61	1	titration	titration	NOUN
admet-400	61	2	of	of	ADP
admet-400	61	3	vancomycin	vancomycin	PROPN
admet-400	61	4	into	into	ADP
admet-400	61	5	liposome	liposome	NOUN
admet-400	61	6	.	.	PUNCT
admet-400	62	1	raw	raw	ADJ
admet-400	62	2	data	datum	NOUN
admet-400	62	3	and	and	CCONJ
admet-400	62	4	fitting	fitting	ADJ
admet-400	62	5	curve	curve	NOUN
admet-400	62	6	of	of	ADP
admet-400	62	7	itc	itc	PROPN
admet-400	62	8	experiment	experiment	NOUN
admet-400	62	9	(	(	PUNCT
admet-400	62	10	left	left	ADJ
admet-400	62	11	)	)	PUNCT
admet-400	62	12	;	;	PUNCT
admet-400	62	13	comparative	comparative	ADJ
admet-400	62	14	fitting	fitting	ADJ
admet-400	62	15	plot	plot	NOUN
admet-400	62	16	of	of	ADP
admet-400	62	17	naficillin	naficillin	NOUN
admet-400	62	18	and	and	CCONJ
admet-400	62	19	vancomycin	vancomycin	PROPN
admet-400	62	20	titration	titration	NOUN
admet-400	62	21	with	with	ADP
admet-400	62	22	liposome	liposome	NOUN
admet-400	62	23	(	(	PUNCT
admet-400	62	24	right	right	NOUN
admet-400	62	25	)	)	PUNCT
admet-400	62	26	.	.	PUNCT
admet-400	63	1	hu	hu	PROPN
admet-400	63	2	and	and	CCONJ
admet-400	63	3	tam	tam	PROPN
admet-400	63	4	admet	admet	PROPN
admet-400	63	5	&	&	CCONJ
admet-400	63	6	dmpk	dmpk	PROPN
admet-400	63	7	5(3	5(3	NUM
admet-400	63	8	)	)	PUNCT
admet-400	63	9	(	(	PUNCT
admet-400	63	10	2017	2017	NUM
admet-400	63	11	)	)	PUNCT
admet-400	63	12	183	183	NUM
admet-400	63	13	-	-	SYM
admet-400	63	14	191	191	NUM
admet-400	63	15	186	186	NUM
admet-400	63	16	vancomycin	vancomycin	PROPN
admet-400	63	17	binds	bind	VERB
admet-400	63	18	to	to	ADP
admet-400	63	19	vesicle	vesicle	NOUN
admet-400	63	20	derived	derive	VERB
admet-400	63	21	from	from	ADP
admet-400	63	22	staphylococcus	staphylococcus	NOUN
admet-400	63	23	aureus	aureus	NOUN
admet-400	63	24	membrane	membrane	NOUN
admet-400	63	25	.	.	PUNCT
admet-400	64	1	now	now	ADV
admet-400	64	2	that	that	SCONJ
admet-400	64	3	we	we	PRON
admet-400	64	4	showed	show	VERB
admet-400	64	5	vancomycin	vancomycin	PROPN
admet-400	64	6	association	association	PROPN
admet-400	64	7	with	with	ADP
admet-400	64	8	membrane	membrane	NOUN
admet-400	64	9	mimic	mimic	ADJ
admet-400	64	10	liposome	liposome	NOUN
admet-400	64	11	,	,	PUNCT
admet-400	64	12	it	it	PRON
admet-400	64	13	is	be	AUX
admet-400	64	14	tempting	tempting	ADJ
admet-400	64	15	to	to	PART
admet-400	64	16	ask	ask	VERB
admet-400	64	17	whether	whether	SCONJ
admet-400	64	18	the	the	DET
admet-400	64	19	antibiotic	antibiotic	NOUN
admet-400	64	20	can	can	AUX
admet-400	64	21	also	also	ADV
admet-400	64	22	bind	bind	VERB
admet-400	64	23	to	to	ADP
admet-400	64	24	vesicle	vesicle	NOUN
admet-400	64	25	derived	derive	VERB
admet-400	64	26	from	from	ADP
admet-400	64	27	biological	biological	ADJ
admet-400	64	28	sample	sample	NOUN
admet-400	64	29	.	.	PUNCT
admet-400	65	1	we	we	PRON
admet-400	65	2	thus	thus	ADV
admet-400	65	3	isolated	isolate	VERB
admet-400	65	4	membrane	membrane	NOUN
admet-400	65	5	from	from	ADP
admet-400	65	6	gram	gram	NOUN
admet-400	65	7	-	-	PUNCT
admet-400	65	8	positive	positive	ADJ
admet-400	65	9	bacterium	bacterium	NOUN
admet-400	65	10	staphylococcus	staphylococcus	NOUN
admet-400	65	11	aureus	aureus	NOUN
admet-400	65	12	by	by	ADP
admet-400	65	13	means	mean	NOUN
admet-400	65	14	of	of	ADP
admet-400	65	15	enzymatic	enzymatic	ADJ
admet-400	65	16	digestion	digestion	NOUN
admet-400	65	17	,	,	PUNCT
admet-400	65	18	mechanical	mechanical	ADJ
admet-400	65	19	disruption	disruption	NOUN
admet-400	65	20	and	and	CCONJ
admet-400	65	21	syringe	syringe	NOUN
admet-400	65	22	needle	needle	NOUN
admet-400	65	23	homogenization	homogenization	NOUN
admet-400	65	24	[	[	X
admet-400	65	25	16	16	NUM
admet-400	65	26	]	]	PUNCT
admet-400	65	27	.	.	PUNCT
admet-400	66	1	resultant	resultant	PROPN
admet-400	66	2	vesicle	vesicle	NOUN
admet-400	66	3	was	be	AUX
admet-400	66	4	then	then	ADV
admet-400	66	5	undergone	undergo	VERB
admet-400	66	6	calorimetric	calorimetric	ADJ
admet-400	66	7	titration	titration	NOUN
admet-400	66	8	with	with	ADP
admet-400	66	9	vancomycin	vancomycin	PROPN
admet-400	66	10	as	as	ADP
admet-400	66	11	the	the	DET
admet-400	66	12	titrant	titrant	NOUN
admet-400	66	13	.	.	PUNCT
admet-400	67	1	according	accord	VERB
admet-400	67	2	to	to	ADP
admet-400	67	3	the	the	DET
admet-400	67	4	fitting	fitting	ADJ
admet-400	67	5	result	result	NOUN
admet-400	67	6	of	of	ADP
admet-400	67	7	itc	itc	PROPN
admet-400	67	8	data	data	PROPN
admet-400	67	9	,	,	PUNCT
admet-400	67	10	vancomycin	vancomycin	PROPN
admet-400	67	11	also	also	ADV
admet-400	67	12	bound	bind	VERB
admet-400	67	13	to	to	ADP
admet-400	67	14	the	the	DET
admet-400	67	15	bacterial	bacterial	ADJ
admet-400	67	16	derived	derive	VERB
admet-400	67	17	vesicle	vesicle	NOUN
admet-400	67	18	(	(	PUNCT
admet-400	67	19	figure	figure	NOUN
admet-400	67	20	2	2	NUM
admet-400	67	21	)	)	PUNCT
admet-400	67	22	,	,	PUNCT
admet-400	67	23	but	but	CCONJ
admet-400	67	24	with	with	ADP
admet-400	67	25	much	much	ADV
admet-400	67	26	higher	high	ADJ
admet-400	67	27	affinity	affinity	NOUN
admet-400	67	28	(	(	PUNCT
admet-400	67	29	sub	sub	NOUN
admet-400	67	30	-	-	ADJ
admet-400	67	31	millimolar	millimolar	ADJ
admet-400	67	32	)	)	PUNCT
admet-400	67	33	than	than	ADP
admet-400	67	34	that	that	PRON
admet-400	67	35	of	of	ADP
admet-400	67	36	liposome	liposome	NOUN
admet-400	67	37	(	(	PUNCT
admet-400	67	38	figure	figure	NOUN
admet-400	67	39	2	2	NUM
admet-400	67	40	)	)	PUNCT
admet-400	67	41	.	.	PUNCT
admet-400	68	1	although	although	SCONJ
admet-400	68	2	we	we	PRON
admet-400	68	3	can	can	AUX
admet-400	68	4	not	not	PART
admet-400	68	5	completely	completely	ADV
admet-400	68	6	rule	rule	VERB
admet-400	68	7	out	out	ADP
admet-400	68	8	the	the	DET
admet-400	68	9	possibility	possibility	NOUN
admet-400	68	10	of	of	ADP
admet-400	68	11	residual	residual	ADJ
admet-400	68	12	peptidoglycan	peptidoglycan	NOUN
admet-400	68	13	remaining	remain	VERB
admet-400	68	14	on	on	ADP
admet-400	68	15	the	the	DET
admet-400	68	16	membrane	membrane	NOUN
admet-400	68	17	,	,	PUNCT
admet-400	68	18	lysozyme	lysozyme	VERB
admet-400	68	19	digestion	digestion	NOUN
admet-400	68	20	step	step	NOUN
admet-400	68	21	of	of	ADP
admet-400	68	22	the	the	DET
admet-400	68	23	cells	cell	NOUN
admet-400	68	24	should	should	AUX
admet-400	68	25	remove	remove	VERB
admet-400	68	26	most	most	ADJ
admet-400	68	27	,	,	PUNCT
admet-400	68	28	if	if	SCONJ
admet-400	68	29	not	not	PART
admet-400	68	30	all	all	PRON
admet-400	68	31	of	of	ADP
admet-400	68	32	them	they	PRON
admet-400	68	33	.	.	PUNCT
admet-400	69	1	apparently	apparently	ADV
admet-400	69	2	,	,	PUNCT
admet-400	69	3	vancomycin	vancomycin	PROPN
admet-400	69	4	binds	bind	VERB
admet-400	69	5	to	to	ADP
admet-400	69	6	the	the	DET
admet-400	69	7	bacterial	bacterial	ADJ
admet-400	69	8	membrane	membrane	NOUN
admet-400	69	9	derived	derive	VERB
admet-400	69	10	vesicle	vesicle	NOUN
admet-400	69	11	with	with	ADP
admet-400	69	12	higher	high	ADJ
admet-400	69	13	affinity	affinity	NOUN
admet-400	69	14	.	.	PUNCT
admet-400	70	1	figure	figure	NOUN
admet-400	70	2	2	2	NUM
admet-400	70	3	.	.	PUNCT
admet-400	71	1	titration	titration	NOUN
admet-400	71	2	of	of	ADP
admet-400	71	3	vancomycin	vancomycin	PROPN
admet-400	71	4	into	into	ADP
admet-400	71	5	vesicle	vesicle	NOUN
admet-400	71	6	derived	derive	VERB
admet-400	71	7	from	from	ADP
admet-400	71	8	staphylococcus	staphylococcus	NOUN
admet-400	71	9	aureus	aureus	NOUN
admet-400	71	10	membrane	membrane	NOUN
admet-400	71	11	.	.	PUNCT
admet-400	72	1	raw	raw	ADJ
admet-400	72	2	data	datum	NOUN
admet-400	72	3	and	and	CCONJ
admet-400	72	4	fitting	fitting	ADJ
admet-400	72	5	curve	curve	NOUN
admet-400	72	6	of	of	ADP
admet-400	72	7	itc	itc	PROPN
admet-400	72	8	experiment	experiment	NOUN
admet-400	72	9	(	(	PUNCT
admet-400	72	10	left	left	ADJ
admet-400	72	11	)	)	PUNCT
admet-400	72	12	;	;	PUNCT
admet-400	72	13	comparative	comparative	ADJ
admet-400	72	14	fitting	fitting	ADJ
admet-400	72	15	plot	plot	NOUN
admet-400	72	16	of	of	ADP
admet-400	72	17	vancomycin	vancomycin	PROPN
admet-400	72	18	titration	titration	NOUN
admet-400	72	19	with	with	ADP
admet-400	72	20	liposome	liposome	NOUN
admet-400	72	21	and	and	CCONJ
admet-400	72	22	vesicle	vesicle	NOUN
admet-400	72	23	from	from	ADP
admet-400	72	24	membrane	membrane	NOUN
admet-400	72	25	(	(	PUNCT
admet-400	72	26	top	top	ADJ
admet-400	72	27	right	right	NOUN
admet-400	72	28	)	)	PUNCT
admet-400	72	29	;	;	PUNCT
admet-400	72	30	size	size	NOUN
admet-400	72	31	distribution	distribution	NOUN
admet-400	72	32	of	of	ADP
admet-400	72	33	liposome	liposome	NOUN
admet-400	72	34	and	and	CCONJ
admet-400	72	35	membrane	membrane	NOUN
admet-400	72	36	vesicle	vesicle	NOUN
admet-400	72	37	determined	determine	VERB
admet-400	72	38	by	by	ADP
admet-400	72	39	dynamic	dynamic	ADJ
admet-400	72	40	light	light	NOUN
admet-400	72	41	scattering	scattering	NOUN
admet-400	72	42	(	(	PUNCT
admet-400	72	43	bottom	bottom	ADJ
admet-400	72	44	right	right	NOUN
admet-400	72	45	)	)	PUNCT
admet-400	72	46	.	.	PUNCT
admet-400	73	1	vancomycin	vancomycin	PROPN
admet-400	73	2	strengthens	strengthen	VERB
admet-400	73	3	the	the	DET
admet-400	73	4	association	association	NOUN
admet-400	73	5	with	with	ADP
admet-400	73	6	liposome	liposome	NOUN
admet-400	73	7	as	as	ADP
admet-400	73	8	its	its	PRON
admet-400	73	9	size	size	NOUN
admet-400	73	10	increases	increase	NOUN
admet-400	73	11	.	.	PUNCT
admet-400	74	1	in	in	ADP
admet-400	74	2	light	light	NOUN
admet-400	74	3	of	of	ADP
admet-400	74	4	differential	differential	ADJ
admet-400	74	5	binding	binding	NOUN
admet-400	74	6	between	between	ADP
admet-400	74	7	liposome	liposome	NOUN
admet-400	74	8	and	and	CCONJ
admet-400	74	9	membrane	membrane	NOUN
admet-400	74	10	-	-	PUNCT
admet-400	74	11	derived	derive	VERB
admet-400	74	12	vesicle	vesicle	NOUN
admet-400	74	13	to	to	ADP
admet-400	74	14	vancomycin	vancomycin	PROPN
admet-400	74	15	and	and	CCONJ
admet-400	74	16	the	the	DET
admet-400	74	17	fact	fact	NOUN
admet-400	74	18	that	that	SCONJ
admet-400	74	19	the	the	DET
admet-400	74	20	later	later	ADV
admet-400	74	21	measured	measure	VERB
admet-400	74	22	much	much	ADV
admet-400	74	23	larger	large	ADJ
admet-400	74	24	in	in	ADP
admet-400	74	25	diameter	diameter	NOUN
admet-400	74	26	than	than	ADP
admet-400	74	27	the	the	DET
admet-400	74	28	former	former	ADJ
admet-400	74	29	(	(	PUNCT
admet-400	74	30	figure	figure	NOUN
admet-400	74	31	2	2	NUM
admet-400	74	32	)	)	PUNCT
admet-400	74	33	,	,	PUNCT
admet-400	74	34	we	we	PRON
admet-400	74	35	speculated	speculate	VERB
admet-400	74	36	that	that	SCONJ
admet-400	74	37	the	the	DET
admet-400	74	38	size	size	NOUN
admet-400	74	39	of	of	ADP
admet-400	74	40	liposome	liposome	NOUN
admet-400	74	41	/	/	SYM
admet-400	74	42	vesicle	vesicle	NOUN
admet-400	74	43	might	might	AUX
admet-400	74	44	play	play	VERB
admet-400	74	45	a	a	DET
admet-400	74	46	role	role	NOUN
admet-400	74	47	in	in	ADP
admet-400	74	48	the	the	DET
admet-400	74	49	antibiotic	antibiotic	ADJ
admet-400	74	50	association	association	NOUN
admet-400	74	51	with	with	ADP
admet-400	74	52	membrane	membrane	NOUN
admet-400	74	53	mimic	mimic	NOUN
admet-400	74	54	.	.	PUNCT
admet-400	75	1	to	to	PART
admet-400	75	2	test	test	VERB
admet-400	75	3	the	the	DET
admet-400	75	4	hypothesis	hypothesis	NOUN
admet-400	75	5	,	,	PUNCT
admet-400	75	6	we	we	PRON
admet-400	75	7	performed	perform	VERB
admet-400	75	8	serial	serial	ADJ
admet-400	75	9	calorimetric	calorimetric	ADJ
admet-400	75	10	titration	titration	NOUN
admet-400	75	11	of	of	ADP
admet-400	75	12	vancomycin	vancomycin	PROPN
admet-400	75	13	into	into	ADP
admet-400	75	14	liposome	liposome	NOUN
admet-400	75	15	prepared	prepare	VERB
admet-400	75	16	with	with	ADP
admet-400	75	17	polycarbonate	polycarbonate	ADJ
admet-400	75	18	membranes	membrane	NOUN
admet-400	75	19	of	of	ADP
admet-400	75	20	various	various	ADJ
admet-400	75	21	sizes	size	NOUN
admet-400	75	22	(	(	PUNCT
admet-400	75	23	0.1	0.1	NUM
admet-400	75	24	,	,	PUNCT
admet-400	75	25	0.4	0.4	NUM
admet-400	75	26	and	and	CCONJ
admet-400	75	27	1	1	NUM
admet-400	75	28	µm	µm	NUM
admet-400	75	29	)	)	PUNCT
admet-400	75	30	.	.	PUNCT
admet-400	76	1	we	we	PRON
admet-400	76	2	found	find	VERB
admet-400	76	3	that	that	SCONJ
admet-400	76	4	the	the	DET
admet-400	76	5	binding	bind	VERB
admet-400	76	6	affinity	affinity	NOUN
admet-400	76	7	of	of	ADP
admet-400	76	8	vancomycin	vancomycin	PROPN
admet-400	76	9	increased	increase	VERB
admet-400	76	10	along	along	ADP
admet-400	76	11	with	with	ADP
admet-400	76	12	liposome	liposome	NOUN
admet-400	76	13	size	size	NOUN
admet-400	76	14	increment	increment	NOUN
admet-400	76	15	.	.	PUNCT
admet-400	77	1	(	(	PUNCT
admet-400	77	2	figure	figure	NOUN
admet-400	77	3	3	3	NUM
admet-400	77	4	)	)	PUNCT
admet-400	77	5	,	,	PUNCT
admet-400	77	6	which	which	PRON
admet-400	77	7	indicated	indicate	VERB
admet-400	77	8	that	that	SCONJ
admet-400	77	9	cell	cell	NOUN
admet-400	77	10	surface	surface	NOUN
admet-400	77	11	landscape	landscape	NOUN
admet-400	77	12	or	or	CCONJ
admet-400	77	13	/	/	SYM
admet-400	77	14	and	and	CCONJ
admet-400	77	15	membrane	membrane	NOUN
admet-400	77	16	curvature	curvature	NOUN
admet-400	77	17	could	could	AUX
admet-400	77	18	be	be	AUX
admet-400	77	19	an	an	DET
admet-400	77	20	important	important	ADJ
admet-400	77	21	factor	factor	NOUN
admet-400	77	22	in	in	ADP
admet-400	77	23	vancomycin	vancomycin	PROPN
admet-400	77	24	association	association	PROPN
admet-400	77	25	.	.	PUNCT
admet-400	78	1	admet	admet	PROPN
admet-400	78	2	&	&	CCONJ
admet-400	78	3	dmpk	dmpk	PROPN
admet-400	78	4	5(3	5(3	NUM
admet-400	78	5	)	)	PUNCT
admet-400	78	6	(	(	PUNCT
admet-400	78	7	2017	2017	NUM
admet-400	78	8	)	)	PUNCT
admet-400	78	9	183	183	NUM
admet-400	78	10	-	-	SYM
admet-400	78	11	191	191	NUM
admet-400	78	12	association	association	NOUN
admet-400	78	13	of	of	ADP
admet-400	78	14	vancomycin	vancomycin	PROPN
admet-400	78	15	with	with	ADP
admet-400	78	16	lipid	lipid	NOUN
admet-400	78	17	vesicles	vesicle	NOUN
admet-400	78	18	doi	doi	NOUN
admet-400	78	19	:	:	PUNCT
admet-400	78	20	10.5599	10.5599	NUM
admet-400	78	21	/	/	SYM
admet-400	78	22	admet.5.3.400	admet.5.3.400	PROPN
admet-400	78	23	187	187	NUM
admet-400	78	24	figure	figure	NOUN
admet-400	78	25	3	3	NUM
admet-400	78	26	.	.	NOUN
admet-400	78	27	size	size	NOUN
admet-400	78	28	-	-	PUNCT
admet-400	78	29	dependent	dependent	ADJ
admet-400	78	30	binding	binding	NOUN
admet-400	78	31	of	of	ADP
admet-400	78	32	liposome	liposome	NOUN
admet-400	78	33	with	with	ADP
admet-400	78	34	vancomycin	vancomycin	PROPN
admet-400	78	35	.	.	PUNCT
admet-400	79	1	data	datum	NOUN
admet-400	79	2	and	and	CCONJ
admet-400	79	3	fitting	fitting	ADJ
admet-400	79	4	curve	curve	NOUN
admet-400	79	5	from	from	ADP
admet-400	79	6	titrations	titration	NOUN
admet-400	79	7	of	of	ADP
admet-400	79	8	liposome	liposome	NOUN
admet-400	79	9	were	be	AUX
admet-400	79	10	plotted	plot	VERB
admet-400	79	11	in	in	ADP
admet-400	79	12	same	same	ADJ
admet-400	79	13	figure	figure	NOUN
admet-400	79	14	for	for	ADP
admet-400	79	15	comparison	comparison	NOUN
admet-400	79	16	(	(	PUNCT
admet-400	79	17	left	left	ADV
admet-400	79	18	)	)	PUNCT
admet-400	79	19	;	;	PUNCT
admet-400	79	20	ka	ka	PROPN
admet-400	79	21	value	value	NOUN
admet-400	79	22	derived	derive	VERB
admet-400	79	23	from	from	ADP
admet-400	79	24	fitting	fitting	ADJ
admet-400	79	25	were	be	AUX
admet-400	79	26	plotted	plot	VERB
admet-400	79	27	against	against	ADP
admet-400	79	28	the	the	DET
admet-400	79	29	sizes	size	NOUN
admet-400	79	30	of	of	ADP
admet-400	79	31	the	the	DET
admet-400	79	32	liposome	liposome	NOUN
admet-400	79	33	(	(	PUNCT
admet-400	79	34	right	right	ADJ
admet-400	79	35	)	)	PUNCT
admet-400	79	36	.	.	PUNCT
admet-400	80	1	vancomycin	vancomycin	PROPN
admet-400	80	2	binds	bind	VERB
admet-400	80	3	preferentially	preferentially	ADV
admet-400	80	4	to	to	PART
admet-400	80	5	popg	popg	VERB
admet-400	80	6	over	over	ADP
admet-400	80	7	cardiolipin	cardiolipin	NOUN
admet-400	80	8	and	and	CCONJ
admet-400	80	9	pope	pope	NOUN
admet-400	80	10	.	.	PUNCT
admet-400	81	1	because	because	SCONJ
admet-400	81	2	the	the	DET
admet-400	81	3	lipids	lipid	NOUN
admet-400	81	4	used	use	VERB
admet-400	81	5	in	in	ADP
admet-400	81	6	the	the	DET
admet-400	81	7	study	study	NOUN
admet-400	81	8	are	be	AUX
admet-400	81	9	similar	similar	ADJ
admet-400	81	10	structurally	structurally	ADV
admet-400	81	11	in	in	ADP
admet-400	81	12	fatty	fatty	NOUN
admet-400	81	13	acid	acid	ADJ
admet-400	81	14	moiety	moiety	NOUN
admet-400	81	15	but	but	CCONJ
admet-400	81	16	vary	vary	VERB
admet-400	81	17	in	in	ADP
admet-400	81	18	head	head	NOUN
admet-400	81	19	groups	group	NOUN
admet-400	81	20	,	,	PUNCT
admet-400	81	21	we	we	PRON
admet-400	81	22	reasoned	reason	VERB
admet-400	81	23	that	that	SCONJ
admet-400	81	24	their	their	PRON
admet-400	81	25	difference	difference	NOUN
admet-400	81	26	in	in	ADP
admet-400	81	27	head	head	NOUN
admet-400	81	28	group	group	NOUN
admet-400	81	29	could	could	AUX
admet-400	81	30	contribute	contribute	VERB
admet-400	81	31	differently	differently	ADV
admet-400	81	32	to	to	ADP
admet-400	81	33	the	the	DET
admet-400	81	34	association	association	NOUN
admet-400	81	35	with	with	ADP
admet-400	81	36	vancomycin	vancomycin	PROPN
admet-400	81	37	.	.	PUNCT
admet-400	82	1	to	to	PART
admet-400	82	2	explore	explore	VERB
admet-400	82	3	binding	bind	VERB
admet-400	82	4	preference	preference	NOUN
admet-400	82	5	of	of	ADP
admet-400	82	6	vancomycin	vancomycin	PROPN
admet-400	82	7	among	among	ADP
admet-400	82	8	lipids	lipid	NOUN
admet-400	82	9	,	,	PUNCT
admet-400	82	10	we	we	PRON
admet-400	82	11	performed	perform	VERB
admet-400	82	12	itc	itc	PROPN
admet-400	82	13	measurement	measurement	NOUN
admet-400	82	14	of	of	ADP
admet-400	82	15	the	the	DET
admet-400	82	16	antibiotic	antibiotic	NOUN
admet-400	82	17	with	with	ADP
admet-400	82	18	liposomes	liposome	NOUN
admet-400	82	19	prepared	prepare	VERB
admet-400	82	20	from	from	ADP
admet-400	82	21	individual	individual	ADJ
admet-400	82	22	lipid	lipid	NOUN
admet-400	82	23	.	.	PUNCT
admet-400	83	1	based	base	VERB
admet-400	83	2	on	on	ADP
admet-400	83	3	the	the	DET
admet-400	83	4	ka	ka	PROPN
admet-400	83	5	value	value	NOUN
admet-400	83	6	derived	derive	VERB
admet-400	83	7	from	from	ADP
admet-400	83	8	data	datum	NOUN
admet-400	83	9	fitting	fitting	ADJ
admet-400	83	10	,	,	PUNCT
admet-400	83	11	binding	bind	VERB
admet-400	83	12	affinity	affinity	NOUN
admet-400	83	13	of	of	ADP
admet-400	83	14	vancomycin	vancomycin	PROPN
admet-400	83	15	to	to	ADP
admet-400	83	16	popg	popg	PROPN
admet-400	83	17	is	be	AUX
admet-400	83	18	significantly	significantly	ADV
admet-400	83	19	higher	high	ADJ
admet-400	83	20	than	than	ADP
admet-400	83	21	that	that	PRON
admet-400	83	22	to	to	ADP
admet-400	83	23	pope	pope	NOUN
admet-400	83	24	and	and	CCONJ
admet-400	83	25	cl	cl	NOUN
admet-400	83	26	(	(	PUNCT
admet-400	83	27	figure	figure	NOUN
admet-400	83	28	4	4	NUM
admet-400	83	29	)	)	PUNCT
admet-400	83	30	,	,	PUNCT
admet-400	83	31	suggesting	suggest	VERB
admet-400	83	32	that	that	SCONJ
admet-400	83	33	popg	popg	PROPN
admet-400	83	34	is	be	AUX
admet-400	83	35	the	the	DET
admet-400	83	36	major	major	ADJ
admet-400	83	37	contributor	contributor	NOUN
admet-400	83	38	to	to	ADP
admet-400	83	39	the	the	DET
admet-400	83	40	association	association	NOUN
admet-400	83	41	of	of	ADP
admet-400	83	42	vancomycin	vancomycin	PROPN
admet-400	83	43	with	with	ADP
admet-400	83	44	liposome	liposome	NOUN
admet-400	83	45	.	.	PUNCT
admet-400	84	1	the	the	DET
admet-400	84	2	observation	observation	NOUN
admet-400	84	3	could	could	AUX
admet-400	84	4	be	be	AUX
admet-400	84	5	explained	explain	VERB
admet-400	84	6	by	by	ADP
admet-400	84	7	careful	careful	ADJ
admet-400	84	8	examination	examination	NOUN
admet-400	84	9	of	of	ADP
admet-400	84	10	the	the	DET
admet-400	84	11	structure	structure	NOUN
admet-400	84	12	of	of	ADP
admet-400	84	13	vancomycin	vancomycin	PROPN
admet-400	85	1	[	[	X
admet-400	85	2	20,21	20,21	NUM
admet-400	85	3	]	]	PUNCT
admet-400	85	4	and	and	CCONJ
admet-400	85	5	the	the	DET
admet-400	85	6	lipids	lipid	NOUN
admet-400	85	7	(	(	PUNCT
admet-400	85	8	figure	figure	NOUN
admet-400	85	9	4	4	NUM
admet-400	85	10	)	)	PUNCT
admet-400	85	11	.	.	PUNCT
admet-400	86	1	positive	positive	ADJ
admet-400	86	2	charged	charge	VERB
admet-400	86	3	amine	amine	NOUN
admet-400	86	4	in	in	ADP
admet-400	86	5	the	the	DET
admet-400	86	6	head	head	NOUN
admet-400	86	7	group	group	NOUN
admet-400	86	8	of	of	ADP
admet-400	86	9	pope	pope	PROPN
admet-400	86	10	does	do	AUX
admet-400	86	11	not	not	PART
admet-400	86	12	appear	appear	VERB
admet-400	86	13	to	to	PART
admet-400	86	14	favour	favour	VERB
admet-400	86	15	the	the	DET
admet-400	86	16	interaction	interaction	NOUN
admet-400	86	17	with	with	ADP
admet-400	86	18	uncharged	uncharged	ADJ
admet-400	86	19	vancomycin	vancomycin	PROPN
admet-400	86	20	.	.	PUNCT
admet-400	87	1	moreover	moreover	ADV
admet-400	87	2	,	,	PUNCT
admet-400	87	3	embedded	embed	VERB
admet-400	87	4	hydroxyl	hydroxyl	NOUN
admet-400	87	5	group	group	NOUN
admet-400	87	6	on	on	ADP
admet-400	87	7	hydrocarbon	hydrocarbon	NOUN
admet-400	87	8	chain	chain	NOUN
admet-400	87	9	within	within	ADP
admet-400	87	10	two	two	NUM
admet-400	87	11	phosphoryl	phosphoryl	NOUN
admet-400	87	12	group	group	NOUN
admet-400	87	13	is	be	AUX
admet-400	87	14	unlikely	unlikely	ADJ
admet-400	87	15	to	to	PART
admet-400	87	16	facilitate	facilitate	VERB
admet-400	87	17	binding	bind	VERB
admet-400	87	18	in	in	ADP
admet-400	87	19	the	the	DET
admet-400	87	20	case	case	NOUN
admet-400	87	21	of	of	ADP
admet-400	87	22	cardiolipin	cardiolipin	NOUN
admet-400	87	23	.	.	PUNCT
admet-400	88	1	on	on	ADP
admet-400	88	2	the	the	DET
admet-400	88	3	other	other	ADJ
admet-400	88	4	hand	hand	NOUN
admet-400	88	5	,	,	PUNCT
admet-400	88	6	the	the	DET
admet-400	88	7	two	two	NUM
admet-400	88	8	hydroxyls	hydroxyls	ADJ
admet-400	88	9	on	on	ADP
admet-400	88	10	the	the	DET
admet-400	88	11	head	head	NOUN
admet-400	88	12	group	group	NOUN
admet-400	88	13	of	of	ADP
admet-400	88	14	the	the	DET
admet-400	88	15	popg	popg	NOUN
admet-400	88	16	could	could	AUX
admet-400	88	17	potentially	potentially	ADV
admet-400	88	18	interact	interact	VERB
admet-400	88	19	with	with	ADP
admet-400	88	20	vancomycin	vancomycin	PROPN
admet-400	88	21	via	via	ADP
admet-400	88	22	hydrogen	hydrogen	NOUN
admet-400	88	23	bond	bond	NOUN
admet-400	88	24	formation	formation	NOUN
admet-400	88	25	,	,	PUNCT
admet-400	88	26	which	which	PRON
admet-400	88	27	promotes	promote	VERB
admet-400	88	28	the	the	DET
admet-400	88	29	glycopeptide	glycopeptide	NOUN
admet-400	88	30	association	association	NOUN
admet-400	88	31	with	with	ADP
admet-400	88	32	lipid	lipid	ADJ
admet-400	88	33	membrane	membrane	NOUN
admet-400	89	1	[	[	X
admet-400	89	2	22	22	NUM
admet-400	89	3	]	]	PUNCT
admet-400	89	4	.	.	PUNCT
admet-400	90	1	vancomycin	vancomycin	PROPN
admet-400	90	2	interaction	interaction	NOUN
admet-400	90	3	with	with	ADP
admet-400	90	4	liposome	liposome	NOUN
admet-400	90	5	does	do	AUX
admet-400	90	6	not	not	PART
admet-400	90	7	involve	involve	VERB
admet-400	90	8	acyl	acyl	NOUN
admet-400	90	9	terminus	terminus	NOUN
admet-400	90	10	of	of	ADP
admet-400	90	11	the	the	DET
admet-400	90	12	lipids	lipid	NOUN
admet-400	90	13	.	.	PUNCT
admet-400	91	1	we	we	PRON
admet-400	91	2	have	have	AUX
admet-400	91	3	shown	show	VERB
admet-400	91	4	that	that	SCONJ
admet-400	91	5	vancomycin	vancomycin	PROPN
admet-400	91	6	associates	associate	NOUN
admet-400	91	7	with	with	ADP
admet-400	91	8	liposome	liposome	NOUN
admet-400	91	9	through	through	ADP
admet-400	91	10	its	its	PRON
admet-400	91	11	interaction	interaction	NOUN
admet-400	91	12	with	with	ADP
admet-400	91	13	the	the	DET
admet-400	91	14	head	head	NOUN
admet-400	91	15	group	group	NOUN
admet-400	91	16	of	of	ADP
admet-400	91	17	the	the	DET
admet-400	91	18	lipids	lipid	NOUN
admet-400	91	19	.	.	PUNCT
admet-400	92	1	but	but	CCONJ
admet-400	92	2	it	it	PRON
admet-400	92	3	remains	remain	VERB
admet-400	92	4	unclear	unclear	ADJ
admet-400	92	5	if	if	SCONJ
admet-400	92	6	the	the	DET
admet-400	92	7	antibiotic	antibiotic	NOUN
admet-400	92	8	could	could	AUX
admet-400	92	9	introduce	introduce	VERB
admet-400	92	10	any	any	DET
admet-400	92	11	change	change	NOUN
admet-400	92	12	inside	inside	ADP
admet-400	92	13	the	the	DET
admet-400	92	14	lipid	lipid	NOUN
admet-400	92	15	bilayer	bilayer	NOUN
admet-400	92	16	.	.	PUNCT
admet-400	93	1	fluorescence	fluorescence	NOUN
admet-400	93	2	spectroscopy	spectroscopy	NOUN
admet-400	93	3	was	be	AUX
admet-400	93	4	performed	perform	VERB
admet-400	93	5	to	to	PART
admet-400	93	6	gain	gain	VERB
admet-400	93	7	more	more	ADJ
admet-400	93	8	insight	insight	NOUN
admet-400	93	9	into	into	ADP
admet-400	93	10	the	the	DET
admet-400	93	11	binding	binding	NOUN
admet-400	93	12	of	of	ADP
admet-400	93	13	vancomycin	vancomycin	PROPN
admet-400	93	14	to	to	PART
admet-400	93	15	liposome	liposome	VERB
admet-400	93	16	.	.	PUNCT
admet-400	94	1	we	we	PRON
admet-400	94	2	incorporated	incorporate	VERB
admet-400	94	3	trace	trace	NOUN
admet-400	94	4	amount	amount	NOUN
admet-400	94	5	(	(	PUNCT
admet-400	94	6	0.5	0.5	NUM
admet-400	94	7	%	%	NOUN
admet-400	94	8	)	)	PUNCT
admet-400	94	9	of	of	ADP
admet-400	94	10	tail	tail	NOUN
admet-400	94	11	fluorescence	fluorescence	NOUN
admet-400	94	12	-	-	PUNCT
admet-400	94	13	labeled	label	VERB
admet-400	94	14	lipid	lipid	NOUN
admet-400	94	15	(	(	PUNCT
admet-400	94	16	ndb	ndb	NOUN
admet-400	94	17	-	-	NOUN
admet-400	94	18	pc	pc	NOUN
admet-400	94	19	)	)	PUNCT
admet-400	94	20	into	into	ADP
admet-400	94	21	liposome	liposome	NOUN
admet-400	94	22	.	.	PUNCT
admet-400	95	1	addition	addition	NOUN
admet-400	95	2	of	of	ADP
admet-400	95	3	stoichiometric	stoichiometric	ADJ
admet-400	95	4	amount	amount	NOUN
admet-400	95	5	of	of	ADP
admet-400	95	6	vancomycin	vancomycin	PROPN
admet-400	95	7	did	do	AUX
admet-400	95	8	not	not	PART
admet-400	95	9	induce	induce	VERB
admet-400	95	10	significant	significant	ADJ
admet-400	95	11	change	change	NOUN
admet-400	95	12	in	in	ADP
admet-400	95	13	the	the	DET
admet-400	95	14	spectrum	spectrum	NOUN
admet-400	95	15	of	of	ADP
admet-400	95	16	the	the	DET
admet-400	95	17	liposome	liposome	NOUN
admet-400	95	18	(	(	PUNCT
admet-400	95	19	figure	figure	NOUN
admet-400	95	20	5	5	NUM
admet-400	95	21	)	)	PUNCT
admet-400	95	22	,	,	PUNCT
admet-400	95	23	suggesting	suggest	VERB
admet-400	95	24	that	that	SCONJ
admet-400	95	25	binding	bind	VERB
admet-400	95	26	of	of	ADP
admet-400	95	27	vancomycin	vancomycin	PROPN
admet-400	95	28	to	to	PART
admet-400	95	29	liposome	liposome	VERB
admet-400	95	30	might	might	AUX
admet-400	95	31	not	not	PART
admet-400	95	32	involve	involve	VERB
admet-400	95	33	the	the	DET
admet-400	95	34	acyl	acyl	ADJ
admet-400	95	35	terminus	terminus	NOUN
admet-400	95	36	of	of	ADP
admet-400	95	37	the	the	DET
admet-400	95	38	lipid	lipid	NOUN
admet-400	95	39	.	.	PUNCT
admet-400	96	1	in	in	ADP
admet-400	96	2	other	other	ADJ
admet-400	96	3	words	word	NOUN
admet-400	96	4	,	,	PUNCT
admet-400	96	5	it	it	PRON
admet-400	96	6	is	be	AUX
admet-400	96	7	unlikely	unlikely	ADJ
admet-400	96	8	for	for	SCONJ
admet-400	96	9	the	the	DET
admet-400	96	10	antibiotic	antibiotic	NOUN
admet-400	96	11	to	to	PART
admet-400	96	12	insert	insert	VERB
admet-400	96	13	deep	deep	ADV
admet-400	96	14	into	into	ADP
admet-400	96	15	the	the	DET
admet-400	96	16	lipids	lipids	ADJ
admet-400	96	17	bilayer	bilayer	NOUN
admet-400	96	18	.	.	PUNCT
admet-400	97	1	otherwise	otherwise	ADV
admet-400	97	2	,	,	PUNCT
admet-400	97	3	alteration	alteration	NOUN
admet-400	97	4	in	in	ADP
admet-400	97	5	fluorescence	fluorescence	NOUN
admet-400	97	6	intensity	intensity	NOUN
admet-400	97	7	or	or	CCONJ
admet-400	97	8	/	/	SYM
admet-400	97	9	and	and	CCONJ
admet-400	97	10	peak	peak	NOUN
admet-400	97	11	position	position	NOUN
admet-400	97	12	shift	shift	NOUN
admet-400	97	13	would	would	AUX
admet-400	97	14	be	be	AUX
admet-400	97	15	obvious	obvious	ADJ
admet-400	97	16	because	because	SCONJ
admet-400	97	17	of	of	ADP
admet-400	97	18	fluorophore	fluorophore	NOUN
admet-400	97	19	disturbing	disturbing	ADJ
admet-400	97	20	by	by	ADP
admet-400	97	21	the	the	DET
admet-400	97	22	insertion	insertion	NOUN
admet-400	97	23	,	,	PUNCT
admet-400	97	24	as	as	SCONJ
admet-400	97	25	seen	see	VERB
admet-400	97	26	in	in	ADP
admet-400	97	27	a	a	DET
admet-400	97	28	control	control	NOUN
admet-400	97	29	experiment	experiment	NOUN
admet-400	97	30	,	,	PUNCT
admet-400	97	31	where	where	SCONJ
admet-400	97	32	pore	pore	ADJ
admet-400	97	33	formation	formation	NOUN
admet-400	97	34	by	by	ADP
admet-400	97	35	depsipeptide	depsipeptide	NOUN
admet-400	97	36	antibiotics	antibiotic	NOUN
admet-400	97	37	,	,	PUNCT
admet-400	97	38	valinomycin	valinomycin	NOUN
admet-400	97	39	[	[	X
admet-400	97	40	23,24	23,24	NOUN
admet-400	97	41	]	]	PUNCT
admet-400	97	42	reduced	reduce	VERB
admet-400	97	43	liposome	liposome	NOUN
admet-400	97	44	fluorescence	fluorescence	NOUN
admet-400	97	45	intensity	intensity	NOUN
admet-400	97	46	substantially	substantially	ADV
admet-400	97	47	.	.	PUNCT
admet-400	98	1	this	this	PRON
admet-400	98	2	is	be	AUX
admet-400	98	3	consistent	consistent	ADJ
admet-400	98	4	with	with	ADP
admet-400	98	5	the	the	DET
admet-400	98	6	fact	fact	NOUN
admet-400	98	7	that	that	SCONJ
admet-400	98	8	vancomycin	vancomycin	PROPN
admet-400	98	9	and	and	CCONJ
admet-400	98	10	other	other	ADJ
admet-400	98	11	glycopeptides	glycopeptide	NOUN
admet-400	98	12	generally	generally	ADV
admet-400	98	13	exhibit	exhibit	VERB
admet-400	98	14	low	low	ADJ
admet-400	98	15	membrane	membrane	NOUN
admet-400	98	16	permeability	permeability	NOUN
admet-400	98	17	[	[	X
admet-400	98	18	3,22	3,22	NOUN
admet-400	98	19	]	]	X
admet-400	98	20	.	.	PUNCT
admet-400	99	1	hu	hu	PROPN
admet-400	99	2	and	and	CCONJ
admet-400	99	3	tam	tam	PROPN
admet-400	99	4	admet	admet	PROPN
admet-400	99	5	&	&	CCONJ
admet-400	99	6	dmpk	dmpk	PROPN
admet-400	99	7	5(3	5(3	NUM
admet-400	99	8	)	)	PUNCT
admet-400	99	9	(	(	PUNCT
admet-400	99	10	2017	2017	NUM
admet-400	99	11	)	)	PUNCT
admet-400	99	12	183	183	NUM
admet-400	99	13	-	-	SYM
admet-400	99	14	191	191	NUM
admet-400	99	15	188	188	NUM
admet-400	99	16	figure	figure	NOUN
admet-400	99	17	4	4	NUM
admet-400	99	18	.	.	PUNCT
admet-400	100	1	vancomycin	vancomycin	PROPN
admet-400	100	2	binds	bind	VERB
admet-400	100	3	preferentially	preferentially	ADV
admet-400	100	4	to	to	PART
admet-400	100	5	popg	popg	VERB
admet-400	100	6	over	over	ADP
admet-400	100	7	pope	pope	NOUN
admet-400	100	8	and	and	CCONJ
admet-400	100	9	cardiolipin	cardiolipin	NOUN
admet-400	100	10	.	.	PUNCT
admet-400	101	1	itc	itc	PROPN
admet-400	101	2	raw	raw	ADJ
admet-400	101	3	data	datum	NOUN
admet-400	101	4	and	and	CCONJ
admet-400	101	5	fitting	fitting	NOUN
admet-400	101	6	of	of	ADP
admet-400	101	7	vancomycin	vancomycin	PROPN
admet-400	101	8	titration	titration	NOUN
admet-400	101	9	with	with	ADP
admet-400	101	10	popg	popg	PROPN
admet-400	101	11	(	(	PUNCT
admet-400	101	12	top	top	NOUN
admet-400	101	13	left	left	ADJ
admet-400	101	14	)	)	PUNCT
admet-400	101	15	,	,	PUNCT
admet-400	101	16	pope	pope	NOUN
admet-400	101	17	(	(	PUNCT
admet-400	101	18	top	top	ADJ
admet-400	101	19	right	right	NOUN
admet-400	101	20	)	)	PUNCT
admet-400	101	21	and	and	CCONJ
admet-400	101	22	cardiolipin	cardiolipin	NOUN
admet-400	101	23	(	(	PUNCT
admet-400	101	24	bottom	bottom	NOUN
admet-400	101	25	left	left	ADJ
admet-400	101	26	)	)	PUNCT
admet-400	101	27	;	;	PUNCT
admet-400	101	28	fitting	fit	VERB
admet-400	101	29	of	of	ADP
admet-400	101	30	titrations	titration	NOUN
admet-400	101	31	were	be	AUX
admet-400	101	32	plotted	plot	VERB
admet-400	101	33	for	for	ADP
admet-400	101	34	comparison	comparison	NOUN
admet-400	101	35	(	(	PUNCT
admet-400	101	36	middle	middle	NOUN
admet-400	101	37	left	left	ADJ
admet-400	101	38	)	)	PUNCT
admet-400	101	39	;	;	PUNCT
admet-400	101	40	structure	structure	NOUN
admet-400	101	41	of	of	ADP
admet-400	101	42	three	three	NUM
admet-400	101	43	lipids	lipid	NOUN
admet-400	101	44	were	be	AUX
admet-400	101	45	shown	show	VERB
admet-400	101	46	(	(	PUNCT
admet-400	101	47	bottom	bottom	ADJ
admet-400	101	48	right	right	NOUN
admet-400	101	49	)	)	PUNCT
admet-400	101	50	.	.	PUNCT
admet-400	102	1	discussion	discussion	NOUN
admet-400	102	2	we	we	PRON
admet-400	102	3	have	have	AUX
admet-400	102	4	shown	show	VERB
admet-400	102	5	that	that	SCONJ
admet-400	102	6	glycopeptide	glycopeptide	NOUN
admet-400	102	7	antibiotics	antibiotic	NOUN
admet-400	102	8	vancomycin	vancomycin	PROPN
admet-400	102	9	associate	associate	VERB
admet-400	102	10	with	with	ADP
admet-400	102	11	biomimetic	biomimetic	ADJ
admet-400	102	12	membrane	membrane	NOUN
admet-400	102	13	,	,	PUNCT
admet-400	102	14	a	a	DET
admet-400	102	15	fact	fact	NOUN
admet-400	102	16	have	have	AUX
admet-400	102	17	been	be	AUX
admet-400	102	18	largely	largely	ADV
admet-400	102	19	ignored	ignore	VERB
admet-400	102	20	in	in	ADP
admet-400	102	21	the	the	DET
admet-400	102	22	field	field	NOUN
admet-400	102	23	because	because	SCONJ
admet-400	102	24	of	of	ADP
admet-400	102	25	its	its	PRON
admet-400	102	26	weak	weak	ADJ
admet-400	102	27	interaction	interaction	NOUN
admet-400	102	28	[	[	X
admet-400	102	29	18,19	18,19	NUM
admet-400	102	30	]	]	PUNCT
admet-400	102	31	.	.	PUNCT
admet-400	103	1	furthermore	furthermore	ADV
admet-400	103	2	,	,	PUNCT
admet-400	103	3	we	we	PRON
admet-400	103	4	showed	show	VERB
admet-400	103	5	for	for	ADP
admet-400	103	6	the	the	DET
admet-400	103	7	first	first	ADJ
admet-400	103	8	time	time	NOUN
admet-400	103	9	that	that	PRON
admet-400	103	10	it	it	PRON
admet-400	103	11	binds	bind	VERB
admet-400	103	12	to	to	ADP
admet-400	103	13	membrane	membrane	NOUN
admet-400	103	14	vesicle	vesicle	NOUN
admet-400	103	15	derived	derive	VERB
admet-400	103	16	from	from	ADP
admet-400	103	17	gram	gram	NOUN
admet-400	103	18	-	-	PUNCT
admet-400	103	19	positive	positive	ADJ
admet-400	103	20	bacteria	bacteria	NOUN
admet-400	103	21	staphylococcus	staphylococcus	NOUN
admet-400	103	22	aureus	aureus	NOUN
admet-400	103	23	admet	admet	PROPN
admet-400	103	24	&	&	CCONJ
admet-400	103	25	dmpk	dmpk	PROPN
admet-400	103	26	5(3	5(3	NUM
admet-400	103	27	)	)	PUNCT
admet-400	103	28	(	(	PUNCT
admet-400	103	29	2017	2017	NUM
admet-400	103	30	)	)	PUNCT
admet-400	103	31	183	183	NUM
admet-400	103	32	-	-	SYM
admet-400	103	33	191	191	NUM
admet-400	103	34	association	association	NOUN
admet-400	103	35	of	of	ADP
admet-400	103	36	vancomycin	vancomycin	PROPN
admet-400	103	37	with	with	ADP
admet-400	103	38	lipid	lipid	NOUN
admet-400	103	39	vesicles	vesicle	NOUN
admet-400	103	40	doi	doi	NOUN
admet-400	103	41	:	:	PUNCT
admet-400	103	42	10.5599	10.5599	NUM
admet-400	103	43	/	/	SYM
admet-400	103	44	admet.5.3.400	admet.5.3.400	PROPN
admet-400	103	45	189	189	NUM
admet-400	103	46	in	in	ADP
admet-400	103	47	a	a	DET
admet-400	103	48	similar	similar	ADJ
admet-400	103	49	fashion	fashion	NOUN
admet-400	103	50	.	.	PUNCT
admet-400	104	1	these	these	DET
admet-400	104	2	observations	observation	NOUN
admet-400	104	3	could	could	AUX
admet-400	104	4	potentially	potentially	ADV
admet-400	104	5	open	open	VERB
admet-400	104	6	a	a	DET
admet-400	104	7	new	new	ADJ
admet-400	104	8	avenue	avenue	NOUN
admet-400	104	9	for	for	ADP
admet-400	104	10	the	the	DET
admet-400	104	11	prototype	prototype	NOUN
admet-400	104	12	antibiotics	antibiotic	NOUN
admet-400	104	13	to	to	PART
admet-400	104	14	tackle	tackle	VERB
admet-400	104	15	infectious	infectious	ADJ
admet-400	104	16	microbes	microbe	NOUN
admet-400	104	17	by	by	ADP
admet-400	104	18	blocking	block	VERB
admet-400	104	19	cell	cell	NOUN
admet-400	104	20	wall	wall	NOUN
admet-400	104	21	synthesis	synthesis	NOUN
admet-400	104	22	and	and	CCONJ
admet-400	104	23	interfering	interfere	VERB
admet-400	104	24	cell	cell	NOUN
admet-400	104	25	membrane	membrane	NOUN
admet-400	104	26	function	function	NOUN
admet-400	104	27	simultaneously	simultaneously	ADV
admet-400	104	28	.	.	PUNCT
admet-400	105	1	multiple	multiple	ADJ
admet-400	105	2	mechanism	mechanism	NOUN
admet-400	105	3	of	of	ADP
admet-400	105	4	action	action	NOUN
admet-400	105	5	is	be	AUX
admet-400	105	6	thought	think	VERB
admet-400	105	7	to	to	PART
admet-400	105	8	be	be	AUX
admet-400	105	9	an	an	DET
admet-400	105	10	effective	effective	ADJ
admet-400	105	11	strategy	strategy	NOUN
admet-400	105	12	to	to	PART
admet-400	105	13	combat	combat	VERB
admet-400	105	14	with	with	ADP
admet-400	105	15	prevalent	prevalent	ADJ
admet-400	105	16	resistance	resistance	NOUN
admet-400	105	17	nowadays	nowadays	ADV
admet-400	105	18	rising	rise	VERB
admet-400	105	19	among	among	ADP
admet-400	105	20	pathological	pathological	ADJ
admet-400	105	21	microorganism	microorganism	NOUN
admet-400	105	22	[	[	X
admet-400	105	23	14,15,25	14,15,25	NUM
admet-400	105	24	]	]	PUNCT
admet-400	105	25	.	.	PUNCT
admet-400	106	1	figure	figure	NOUN
admet-400	106	2	5	5	NUM
admet-400	106	3	.	.	PUNCT
admet-400	107	1	fluorescence	fluorescence	PROPN
admet-400	107	2	spectra	spectra	NOUN
admet-400	107	3	of	of	ADP
admet-400	107	4	liposome	liposome	NOUN
admet-400	107	5	with	with	ADP
admet-400	107	6	fluorescent	fluorescent	ADJ
admet-400	107	7	label	label	NOUN
admet-400	107	8	.	.	PUNCT
admet-400	108	1	left	leave	VERB
admet-400	108	2	panel	panel	NOUN
admet-400	108	3	,	,	PUNCT
admet-400	108	4	spectra	spectra	NOUN
admet-400	108	5	of	of	ADP
admet-400	108	6	3.5	3.5	NUM
admet-400	108	7	mm	mm	NOUN
admet-400	108	8	liposome	liposome	NOUN
admet-400	108	9	containing	contain	VERB
admet-400	108	10	0.5	0.5	NUM
admet-400	108	11	%	%	NOUN
admet-400	108	12	ndb	ndb	NOUN
admet-400	108	13	pc	pc	NOUN
admet-400	108	14	in	in	ADP
admet-400	108	15	the	the	DET
admet-400	108	16	absence	absence	NOUN
admet-400	108	17	(	(	PUNCT
admet-400	108	18	green	green	ADJ
admet-400	108	19	line	line	NOUN
admet-400	108	20	)	)	PUNCT
admet-400	108	21	and	and	CCONJ
admet-400	108	22	presence	presence	NOUN
admet-400	108	23	(	(	PUNCT
admet-400	108	24	red	red	ADJ
admet-400	108	25	line	line	NOUN
admet-400	108	26	)	)	PUNCT
admet-400	108	27	of	of	ADP
admet-400	108	28	5	5	NUM
admet-400	108	29	mm	mm	NOUN
admet-400	108	30	vancomycin	vancomycin	PROPN
admet-400	108	31	;	;	PUNCT
admet-400	108	32	right	right	ADJ
admet-400	108	33	panel	panel	NOUN
admet-400	108	34	,	,	PUNCT
admet-400	108	35	spectra	spectra	NOUN
admet-400	108	36	of	of	ADP
admet-400	108	37	1.5	1.5	NUM
admet-400	108	38	mm	mm	NOUN
admet-400	108	39	liposome	liposome	NOUN
admet-400	108	40	containing	contain	VERB
admet-400	108	41	0.5	0.5	NUM
admet-400	108	42	%	%	NOUN
admet-400	108	43	ndb	ndb	NOUN
admet-400	108	44	pc	pc	NOUN
admet-400	108	45	in	in	ADP
admet-400	108	46	the	the	DET
admet-400	108	47	absence	absence	NOUN
admet-400	108	48	(	(	PUNCT
admet-400	108	49	green	green	ADJ
admet-400	108	50	line	line	NOUN
admet-400	108	51	)	)	PUNCT
admet-400	108	52	and	and	CCONJ
admet-400	108	53	presence	presence	NOUN
admet-400	108	54	(	(	PUNCT
admet-400	108	55	red	red	ADJ
admet-400	108	56	line	line	NOUN
admet-400	108	57	)	)	PUNCT
admet-400	108	58	of	of	ADP
admet-400	108	59	2	2	NUM
admet-400	108	60	mm	mm	NOUN
admet-400	108	61	valinomycin	valinomycin	NOUN
admet-400	108	62	.	.	PUNCT
admet-400	109	1	we	we	PRON
admet-400	109	2	also	also	ADV
admet-400	109	3	found	find	VERB
admet-400	109	4	that	that	SCONJ
admet-400	109	5	vancomycin	vancomycin	PROPN
admet-400	109	6	appears	appear	VERB
admet-400	109	7	to	to	PART
admet-400	109	8	bind	bind	VERB
admet-400	109	9	to	to	ADP
admet-400	109	10	the	the	DET
admet-400	109	11	membrane	membrane	NOUN
admet-400	109	12	from	from	ADP
admet-400	109	13	outside	outside	ADV
admet-400	109	14	and	and	CCONJ
admet-400	109	15	the	the	DET
admet-400	109	16	extent	extent	NOUN
admet-400	109	17	of	of	ADP
admet-400	109	18	association	association	NOUN
admet-400	109	19	depends	depend	VERB
admet-400	109	20	much	much	ADV
admet-400	109	21	on	on	ADP
admet-400	109	22	local	local	ADJ
admet-400	109	23	phospholipid	phospholipid	NOUN
admet-400	109	24	composition	composition	NOUN
admet-400	109	25	and	and	CCONJ
admet-400	109	26	the	the	DET
admet-400	109	27	curvature	curvature	NOUN
admet-400	109	28	of	of	ADP
admet-400	109	29	the	the	DET
admet-400	109	30	membrane	membrane	NOUN
admet-400	109	31	.	.	PUNCT
admet-400	110	1	popg	popg	PROPN
admet-400	110	2	appears	appear	VERB
admet-400	110	3	to	to	PART
admet-400	110	4	be	be	AUX
admet-400	110	5	the	the	DET
admet-400	110	6	favourite	favourite	ADJ
admet-400	110	7	target	target	NOUN
admet-400	110	8	for	for	ADP
admet-400	110	9	vancomycin	vancomycin	PROPN
admet-400	110	10	binding	bind	VERB
admet-400	110	11	.	.	PUNCT
admet-400	111	1	moreover	moreover	ADV
admet-400	111	2	larger	large	ADJ
admet-400	111	3	size	size	NOUN
admet-400	111	4	(	(	PUNCT
admet-400	111	5	flattened	flatten	VERB
admet-400	111	6	surface	surface	NOUN
admet-400	111	7	)	)	PUNCT
admet-400	111	8	of	of	ADP
admet-400	111	9	the	the	DET
admet-400	111	10	liposome	liposome	NOUN
admet-400	111	11	enhances	enhance	VERB
admet-400	111	12	the	the	DET
admet-400	111	13	binding	binding	NOUN
admet-400	111	14	.	.	PUNCT
admet-400	112	1	these	these	DET
admet-400	112	2	findings	finding	NOUN
admet-400	112	3	could	could	AUX
admet-400	112	4	provide	provide	VERB
admet-400	112	5	some	some	DET
admet-400	112	6	design	design	NOUN
admet-400	112	7	ideas	idea	NOUN
admet-400	112	8	for	for	ADP
admet-400	112	9	further	further	ADJ
admet-400	112	10	modification	modification	NOUN
admet-400	112	11	of	of	ADP
admet-400	112	12	the	the	DET
admet-400	112	13	antibiotics	antibiotic	NOUN
admet-400	112	14	to	to	PART
admet-400	112	15	optimize	optimize	VERB
admet-400	112	16	its	its	PRON
admet-400	112	17	binding	binding	NOUN
admet-400	112	18	to	to	ADP
admet-400	112	19	bacterial	bacterial	ADJ
admet-400	112	20	membrane	membrane	NOUN
admet-400	112	21	,	,	PUNCT
admet-400	112	22	which	which	PRON
admet-400	112	23	may	may	AUX
admet-400	112	24	improve	improve	VERB
admet-400	112	25	antibacterial	antibacterial	ADJ
admet-400	112	26	potency	potency	NOUN
admet-400	112	27	.	.	PUNCT
admet-400	113	1	to	to	ADP
admet-400	113	2	this	this	DET
admet-400	113	3	end	end	NOUN
admet-400	113	4	,	,	PUNCT
admet-400	113	5	a	a	DET
admet-400	113	6	further	further	ADJ
admet-400	113	7	investigation	investigation	NOUN
admet-400	113	8	of	of	ADP
admet-400	113	9	vancomycin	vancomycin	PROPN
admet-400	113	10	structure	structure	NOUN
admet-400	113	11	and	and	CCONJ
admet-400	113	12	bacterial	bacterial	ADJ
admet-400	113	13	membrane	membrane	NOUN
admet-400	113	14	composition	composition	NOUN
admet-400	113	15	is	be	AUX
admet-400	113	16	required	require	VERB
admet-400	113	17	.	.	PUNCT
admet-400	114	1	in	in	ADP
admet-400	114	2	addition	addition	NOUN
admet-400	114	3	,	,	PUNCT
admet-400	114	4	self	self	NOUN
admet-400	114	5	[	[	X
admet-400	114	6	20,21	20,21	NUM
admet-400	114	7	]	]	PUNCT
admet-400	114	8	and	and	CCONJ
admet-400	114	9	ligand	ligand	NOUN
admet-400	114	10	-	-	PUNCT
admet-400	114	11	induced	induce	VERB
admet-400	114	12	dimerization	dimerization	NOUN
admet-400	114	13	[	[	X
admet-400	114	14	26,27	26,27	NUM
admet-400	114	15	]	]	PUNCT
admet-400	114	16	of	of	ADP
admet-400	114	17	vancomycin	vancomycin	PROPN
admet-400	114	18	might	might	AUX
admet-400	114	19	also	also	ADV
admet-400	114	20	play	play	VERB
admet-400	114	21	an	an	DET
admet-400	114	22	important	important	ADJ
admet-400	114	23	role	role	NOUN
admet-400	114	24	as	as	ADP
admet-400	114	25	a	a	DET
admet-400	114	26	larger	large	ADJ
admet-400	114	27	hydrophobic	hydrophobic	NOUN
admet-400	114	28	interface	interface	NOUN
admet-400	114	29	once	once	ADV
admet-400	114	30	shielded	shield	VERB
admet-400	114	31	by	by	ADP
admet-400	114	32	dimeric	dimeric	ADJ
admet-400	114	33	interaction	interaction	NOUN
admet-400	114	34	has	have	VERB
admet-400	114	35	to	to	PART
admet-400	114	36	be	be	AUX
admet-400	114	37	covered	cover	VERB
admet-400	114	38	by	by	ADP
admet-400	114	39	membrane	membrane	NOUN
admet-400	114	40	association	association	NOUN
admet-400	114	41	.	.	PUNCT
admet-400	115	1	conclusions	conclusion	NOUN
admet-400	115	2	we	we	PRON
admet-400	115	3	have	have	AUX
admet-400	115	4	studied	study	VERB
admet-400	115	5	the	the	DET
admet-400	115	6	binding	binding	NOUN
admet-400	115	7	of	of	ADP
admet-400	115	8	vancomycin	vancomycin	PROPN
admet-400	115	9	to	to	ADP
admet-400	115	10	biomimetic	biomimetic	ADJ
admet-400	115	11	membranes	membrane	NOUN
admet-400	115	12	based	base	VERB
admet-400	115	13	on	on	ADP
admet-400	115	14	three	three	NUM
admet-400	115	15	phospholipid	phospholipid	NOUN
admet-400	115	16	components	component	NOUN
admet-400	115	17	and	and	CCONJ
admet-400	115	18	bacterial	bacterial	ADJ
admet-400	115	19	membranes	membrane	NOUN
admet-400	115	20	by	by	ADP
admet-400	115	21	using	use	VERB
admet-400	115	22	a	a	DET
admet-400	115	23	variety	variety	NOUN
admet-400	115	24	of	of	ADP
admet-400	115	25	biophysical	biophysical	ADJ
admet-400	115	26	methods	method	NOUN
admet-400	115	27	,	,	PUNCT
admet-400	115	28	including	include	VERB
admet-400	115	29	isothermal	isothermal	ADJ
admet-400	115	30	calorimetry	calorimetry	NOUN
admet-400	115	31	and	and	CCONJ
admet-400	115	32	fluorescence	fluorescence	NOUN
admet-400	115	33	photometry	photometry	NOUN
admet-400	115	34	.	.	PUNCT
admet-400	116	1	it	it	PRON
admet-400	116	2	has	have	AUX
admet-400	116	3	been	be	AUX
admet-400	116	4	shown	show	VERB
admet-400	116	5	that	that	SCONJ
admet-400	116	6	the	the	DET
admet-400	116	7	ways	way	NOUN
admet-400	116	8	of	of	ADP
admet-400	116	9	association	association	NOUN
admet-400	116	10	of	of	ADP
admet-400	116	11	vancomycin	vancomycin	PROPN
admet-400	116	12	to	to	ADP
admet-400	116	13	biomimetic	biomimetic	ADJ
admet-400	116	14	membranes	membrane	NOUN
admet-400	116	15	is	be	AUX
admet-400	116	16	very	very	ADV
admet-400	116	17	similar	similar	ADJ
admet-400	116	18	to	to	ADP
admet-400	116	19	that	that	PRON
admet-400	116	20	of	of	ADP
admet-400	116	21	vesicle	vesicle	NOUN
admet-400	116	22	derived	derive	VERB
admet-400	116	23	from	from	ADP
admet-400	116	24	staphylococcus	staphylococcus	NOUN
admet-400	116	25	aureus	aureus	NOUN
admet-400	116	26	membrane	membrane	NOUN
admet-400	116	27	.	.	PUNCT
admet-400	117	1	our	our	PRON
admet-400	117	2	results	result	NOUN
admet-400	117	3	clearly	clearly	ADV
admet-400	117	4	indicated	indicate	VERB
admet-400	117	5	that	that	SCONJ
admet-400	117	6	vancomycin	vancomycin	PROPN
admet-400	117	7	associates	associate	NOUN
admet-400	117	8	to	to	ADP
admet-400	117	9	the	the	DET
admet-400	117	10	cell	cell	NOUN
admet-400	117	11	membrane	membrane	NOUN
admet-400	117	12	from	from	ADP
admet-400	117	13	outside	outside	ADV
admet-400	117	14	,	,	PUNCT
admet-400	117	15	and	and	CCONJ
admet-400	117	16	does	do	AUX
admet-400	117	17	not	not	PART
admet-400	117	18	permeate	permeate	VERB
admet-400	117	19	through	through	ADP
admet-400	117	20	the	the	DET
admet-400	117	21	cell	cell	NOUN
admet-400	117	22	membrane	membrane	NOUN
admet-400	117	23	,	,	PUNCT
admet-400	117	24	which	which	PRON
admet-400	117	25	is	be	AUX
admet-400	117	26	consistent	consistent	ADJ
admet-400	117	27	with	with	ADP
admet-400	117	28	the	the	DET
admet-400	117	29	mechanisms	mechanism	NOUN
admet-400	117	30	of	of	ADP
admet-400	117	31	the	the	DET
admet-400	117	32	drug	drug	NOUN
admet-400	117	33	action	action	NOUN
admet-400	117	34	.	.	PUNCT
admet-400	118	1	by	by	ADP
admet-400	118	2	varying	vary	VERB
admet-400	118	3	the	the	DET
admet-400	118	4	size	size	NOUN
admet-400	118	5	and	and	CCONJ
admet-400	118	6	composition	composition	NOUN
admet-400	118	7	of	of	ADP
admet-400	118	8	the	the	DET
admet-400	118	9	biomimetic	biomimetic	ADJ
admet-400	118	10	membrane	membrane	NOUN
admet-400	118	11	vesicles	vesicle	NOUN
admet-400	118	12	,	,	PUNCT
admet-400	118	13	it	it	PRON
admet-400	118	14	has	have	AUX
admet-400	118	15	been	be	AUX
admet-400	118	16	demonstrated	demonstrate	VERB
admet-400	118	17	that	that	SCONJ
admet-400	118	18	the	the	DET
admet-400	118	19	extent	extent	NOUN
admet-400	118	20	of	of	ADP
admet-400	118	21	association	association	NOUN
admet-400	118	22	depends	depend	VERB
admet-400	118	23	on	on	ADP
admet-400	118	24	specific	specific	ADJ
admet-400	118	25	type	type	NOUN
admet-400	118	26	of	of	ADP
admet-400	118	27	lipids	lipid	NOUN
admet-400	118	28	and	and	CCONJ
admet-400	118	29	curvature	curvature	NOUN
admet-400	118	30	of	of	ADP
admet-400	118	31	local	local	ADJ
admet-400	118	32	membrane	membrane	NOUN
admet-400	118	33	structure	structure	NOUN
admet-400	118	34	.	.	PUNCT
admet-400	119	1	these	these	DET
admet-400	119	2	observations	observation	NOUN
admet-400	119	3	could	could	AUX
admet-400	119	4	potentially	potentially	ADV
admet-400	119	5	open	open	VERB
admet-400	119	6	a	a	DET
admet-400	119	7	new	new	ADJ
admet-400	119	8	avenue	avenue	NOUN
admet-400	119	9	to	to	PART
admet-400	119	10	revive	revive	VERB
admet-400	119	11	the	the	DET
admet-400	119	12	prototype	prototype	NOUN
admet-400	119	13	antibiotic	antibiotic	ADJ
admet-400	119	14	to	to	PART
admet-400	119	15	fight	fight	VERB
admet-400	119	16	infectious	infectious	ADJ
admet-400	119	17	microbe	microbe	NOUN
admet-400	119	18	through	through	ADP
admet-400	119	19	the	the	DET
admet-400	119	20	design	design	NOUN
admet-400	119	21	of	of	ADP
admet-400	119	22	specific	specific	ADJ
admet-400	119	23	tight	tight	ADJ
admet-400	119	24	binders	binder	NOUN
admet-400	119	25	to	to	ADP
admet-400	119	26	the	the	DET
admet-400	119	27	outer	outer	ADJ
admet-400	119	28	surface	surface	NOUN
admet-400	119	29	of	of	ADP
admet-400	119	30	bacterial	bacterial	ADJ
admet-400	119	31	membranes	membrane	NOUN
admet-400	119	32	to	to	PART
admet-400	119	33	impede	impede	VERB
admet-400	119	34	cell	cell	NOUN
admet-400	119	35	wall	wall	NOUN
admet-400	119	36	synthesis	synthesis	PROPN
admet-400	119	37	.	.	PUNCT
admet-400	120	1	hu	hu	PROPN
admet-400	120	2	and	and	CCONJ
admet-400	120	3	tam	tam	PROPN
admet-400	120	4	admet	admet	PROPN
admet-400	120	5	&	&	CCONJ
admet-400	120	6	dmpk	dmpk	PROPN
admet-400	120	7	5(3	5(3	NUM
admet-400	120	8	)	)	PUNCT
admet-400	120	9	(	(	PUNCT
admet-400	120	10	2017	2017	NUM
admet-400	120	11	)	)	PUNCT
admet-400	120	12	183	183	NUM
admet-400	120	13	-	-	SYM
admet-400	120	14	191	191	NUM
admet-400	120	15	190	190	NUM
admet-400	120	16	acknowledgements	acknowledgement	NOUN
admet-400	120	17	:	:	PUNCT
admet-400	120	18	we	we	PRON
admet-400	120	19	thank	thank	VERB
admet-400	120	20	the	the	DET
admet-400	120	21	financial	financial	ADJ
admet-400	120	22	support	support	NOUN
admet-400	120	23	from	from	ADP
admet-400	120	24	the	the	DET
admet-400	120	25	university	university	PROPN
admet-400	120	26	of	of	ADP
admet-400	120	27	macau	macau	PROPN
admet-400	120	28	(	(	PUNCT
admet-400	120	29	grant	grant	VERB
admet-400	120	30	no	no	INTJ
admet-400	120	31	.	.	PUNCT
admet-400	120	32	:	:	PUNCT
admet-400	120	33	srg201300055	srg201300055	NOUN
admet-400	120	34	-	-	PUNCT
admet-400	120	35	fhs	fh	VERB
admet-400	120	36	)	)	PUNCT
admet-400	120	37	.	.	PUNCT
admet-400	121	1	we	we	PRON
admet-400	121	2	thank	thank	VERB
admet-400	121	3	prof	prof	PROPN
admet-400	121	4	jun	jun	PROPN
admet-400	121	5	zheng	zheng	PROPN
admet-400	121	6	(	(	PUNCT
admet-400	121	7	university	university	PROPN
admet-400	121	8	of	of	ADP
admet-400	121	9	macau	macau	PROPN
admet-400	121	10	)	)	PUNCT
admet-400	121	11	for	for	ADP
admet-400	121	12	providing	provide	VERB
admet-400	121	13	a	a	DET
admet-400	121	14	bacteria	bacteria	NOUN
admet-400	121	15	strain	strain	NOUN
admet-400	121	16	of	of	ADP
admet-400	121	17	staphylococcus	staphylococcus	NOUN
admet-400	121	18	aureus	aureus	NOUN
admet-400	121	19	.	.	PUNCT
admet-400	122	1	references	reference	NOUN
admet-400	122	2	[	[	X
admet-400	122	3	1	1	NUM
admet-400	122	4	]	]	X
admet-400	122	5	l.l	l.l	PROPN
admet-400	122	6	.	.	PROPN
admet-400	122	7	silver	silver	NOUN
admet-400	122	8	.	.	PUNCT
admet-400	123	1	challenges	challenge	NOUN
admet-400	123	2	of	of	ADP
admet-400	123	3	antibacterial	antibacterial	ADJ
admet-400	123	4	discovery	discovery	NOUN
admet-400	123	5	.	.	PUNCT
admet-400	124	1	clin	clin	PROPN
admet-400	124	2	.	.	PUNCT
admet-400	125	1	microbiol	microbiol	PROPN
admet-400	125	2	.	.	PUNCT
admet-400	126	1	rev	rev	PROPN
admet-400	126	2	.	.	PROPN
admet-400	126	3	,	,	PUNCT
admet-400	126	4	24	24	NUM
admet-400	126	5	(	(	PUNCT
admet-400	126	6	2011	2011	NUM
admet-400	126	7	)	)	PUNCT
admet-400	127	1	71–109	71–109	NUM
admet-400	127	2	.	.	PUNCT
admet-400	128	1	[	[	X
admet-400	128	2	2	2	NUM
admet-400	128	3	]	]	X
admet-400	128	4	m.a	m.a	PROPN
admet-400	128	5	.	.	PROPN
admet-400	128	6	fischbach	fischbach	PROPN
admet-400	128	7	,	,	PUNCT
admet-400	128	8	c.t	c.t	PROPN
admet-400	128	9	.	.	PROPN
admet-400	128	10	walsh	walsh	PROPN
admet-400	128	11	.	.	PUNCT
admet-400	129	1	antibiotics	antibiotic	NOUN
admet-400	129	2	for	for	ADP
admet-400	129	3	emerging	emerge	VERB
admet-400	129	4	pathogens	pathogen	NOUN
admet-400	129	5	.	.	PUNCT
admet-400	130	1	science	science	NOUN
admet-400	130	2	,	,	PUNCT
admet-400	130	3	325	325	NUM
admet-400	130	4	(	(	PUNCT
admet-400	130	5	2009	2009	NUM
admet-400	130	6	)	)	PUNCT
admet-400	130	7	1089–93	1089–93	NUM
admet-400	130	8	.	.	PUNCT
admet-400	131	1	[	[	X
admet-400	131	2	3	3	NUM
admet-400	131	3	]	]	X
admet-400	131	4	m.a	m.a	PROPN
admet-400	131	5	.	.	PROPN
admet-400	131	6	kohanski	kohanski	PROPN
admet-400	131	7	,	,	PUNCT
admet-400	131	8	d.j	d.j	PROPN
admet-400	131	9	.	.	PROPN
admet-400	131	10	dwyer	dwyer	PROPN
admet-400	131	11	,	,	PUNCT
admet-400	131	12	j.j	j.j	PROPN
admet-400	131	13	.	.	PROPN
admet-400	131	14	collins	collins	PROPN
admet-400	131	15	.	.	PUNCT
admet-400	132	1	how	how	SCONJ
admet-400	132	2	antibiotics	antibiotic	NOUN
admet-400	132	3	kill	kill	VERB
admet-400	132	4	bacteria	bacteria	NOUN
admet-400	132	5	:	:	PUNCT
admet-400	132	6	from	from	ADP
admet-400	132	7	targets	target	NOUN
admet-400	132	8	to	to	ADP
admet-400	132	9	networks	network	NOUN
admet-400	132	10	.	.	PUNCT
admet-400	133	1	nat	nat	PROPN
admet-400	133	2	.	.	PUNCT
admet-400	134	1	rev	rev	PROPN
admet-400	134	2	.	.	PROPN
admet-400	134	3	microbiol	microbiol	PROPN
admet-400	134	4	.	.	PUNCT
admet-400	135	1	,	,	PUNCT
admet-400	135	2	8	8	NUM
admet-400	135	3	(	(	PUNCT
admet-400	135	4	2010	2010	NUM
admet-400	135	5	)	)	PUNCT
admet-400	135	6	423–35	423–35	NUM
admet-400	135	7	.	.	PUNCT
admet-400	136	1	[	[	X
admet-400	136	2	4	4	NUM
admet-400	136	3	]	]	PUNCT
admet-400	136	4	m.	m.	NOUN
admet-400	136	5	zasloff	zasloff	NOUN
admet-400	136	6	.	.	PUNCT
admet-400	137	1	antimicrobial	antimicrobial	ADJ
admet-400	137	2	peptides	peptide	NOUN
admet-400	137	3	of	of	ADP
admet-400	137	4	multicellular	multicellular	ADJ
admet-400	137	5	organisms	organism	NOUN
admet-400	137	6	.	.	PUNCT
admet-400	138	1	nature	nature	NOUN
admet-400	138	2	,	,	PUNCT
admet-400	138	3	415	415	NUM
admet-400	138	4	(	(	PUNCT
admet-400	138	5	2002	2002	NUM
admet-400	138	6	)	)	PUNCT
admet-400	139	1	389–395	389–395	NUM
admet-400	139	2	.	.	PUNCT
admet-400	140	1	[	[	X
admet-400	140	2	5	5	NUM
admet-400	140	3	]	]	X
admet-400	140	4	k.a	k.a	PROPN
admet-400	140	5	.	.	PUNCT
admet-400	140	6	brogden	brogden	PROPN
admet-400	140	7	.	.	PUNCT
admet-400	141	1	antimicrobial	antimicrobial	ADJ
admet-400	141	2	peptides	peptide	NOUN
admet-400	141	3	:	:	PUNCT
admet-400	141	4	pore	pore	ADJ
admet-400	141	5	formers	former	NOUN
admet-400	141	6	or	or	CCONJ
admet-400	141	7	metabolic	metabolic	NOUN
admet-400	141	8	inhibitors	inhibitor	NOUN
admet-400	141	9	in	in	ADP
admet-400	141	10	bacteria	bacteria	NOUN
admet-400	141	11	?	?	PUNCT
admet-400	141	12	.	.	PUNCT
admet-400	142	1	nat	nat	PROPN
admet-400	142	2	.	.	PUNCT
admet-400	143	1	rev	rev	PROPN
admet-400	143	2	.	.	PROPN
admet-400	143	3	microbiol	microbiol	PROPN
admet-400	143	4	.	.	PUNCT
admet-400	143	5	,	,	PUNCT
admet-400	143	6	3	3	NUM
admet-400	143	7	(	(	PUNCT
admet-400	143	8	2005	2005	NUM
admet-400	143	9	)	)	PUNCT
admet-400	144	1	238–250	238–250	NUM
admet-400	144	2	.	.	PUNCT
admet-400	145	1	[	[	X
admet-400	145	2	6	6	NUM
admet-400	145	3	]	]	PUNCT
admet-400	145	4	t.	t.	NOUN
admet-400	145	5	velkov	velkov	PROPN
admet-400	145	6	,	,	PUNCT
admet-400	145	7	p.e	p.e	PROPN
admet-400	145	8	.	.	PROPN
admet-400	145	9	thompson	thompson	PROPN
admet-400	145	10	,	,	PUNCT
admet-400	145	11	r.l	r.l	PROPN
admet-400	145	12	.	.	PROPN
admet-400	145	13	nation	nation	PROPN
admet-400	145	14	,	,	PUNCT
admet-400	145	15	j.	j.	PROPN
admet-400	145	16	li	li	PROPN
admet-400	145	17	.	.	PROPN
admet-400	145	18	structure	structure	NOUN
admet-400	145	19	-	-	PUNCT
admet-400	145	20	activity	activity	NOUN
admet-400	145	21	relationships	relationship	NOUN
admet-400	145	22	of	of	ADP
admet-400	145	23	polymyxin	polymyxin	ADJ
admet-400	145	24	antibiotics	antibiotic	NOUN
admet-400	145	25	.	.	PUNCT
admet-400	146	1	j.	j.	PROPN
admet-400	146	2	med	med	PROPN
admet-400	146	3	.	.	PROPN
admet-400	146	4	chem	chem	PROPN
admet-400	146	5	.	.	PUNCT
admet-400	146	6	,	,	PUNCT
admet-400	146	7	53	53	NUM
admet-400	146	8	(	(	PUNCT
admet-400	146	9	2010	2010	NUM
admet-400	146	10	)	)	PUNCT
admet-400	146	11	1898–1916	1898–1916	NUM
admet-400	146	12	.	.	PUNCT
admet-400	147	1	[	[	X
admet-400	147	2	7	7	X
admet-400	147	3	]	]	X
admet-400	147	4	s.	s.	PROPN
admet-400	147	5	mukherjee	mukherjee	PROPN
admet-400	147	6	,	,	PUNCT
admet-400	147	7	h.	h.	PROPN
admet-400	147	8	zheng	zheng	PROPN
admet-400	147	9	,	,	PUNCT
admet-400	147	10	m.g	m.g	PROPN
admet-400	147	11	.	.	PROPN
admet-400	147	12	derebe	derebe	PROPN
admet-400	147	13	,	,	PUNCT
admet-400	147	14	k.m	k.m	PROPN
admet-400	147	15	.	.	PROPN
admet-400	147	16	callenberg	callenberg	PROPN
admet-400	147	17	,	,	PUNCT
admet-400	147	18	c.l	c.l	PROPN
admet-400	147	19	.	.	PROPN
admet-400	147	20	partch	partch	PROPN
admet-400	147	21	,	,	PUNCT
admet-400	147	22	d.	d.	PROPN
admet-400	147	23	rollins	rollins	PROPN
admet-400	147	24	,	,	PUNCT
admet-400	147	25	d.c	d.c	PROPN
admet-400	147	26	.	.	PROPN
admet-400	147	27	propheter	propheter	PROPN
admet-400	147	28	,	,	PUNCT
admet-400	147	29	j.	j.	PROPN
admet-400	147	30	rizo	rizo	PROPN
admet-400	147	31	,	,	PUNCT
admet-400	147	32	m.	m.	PROPN
admet-400	147	33	grabe	grabe	PROPN
admet-400	147	34	,	,	PUNCT
admet-400	147	35	q.-x	q.-x	PROPN
admet-400	147	36	.	.	PUNCT
admet-400	148	1	jiang	jiang	PROPN
admet-400	148	2	,	,	PUNCT
admet-400	148	3	l.	l.	PROPN
admet-400	148	4	v	v	PROPN
admet-400	148	5	hooper	hooper	PROPN
admet-400	148	6	.	.	PUNCT
admet-400	149	1	antibacterial	antibacterial	ADJ
admet-400	149	2	membrane	membrane	NOUN
admet-400	149	3	attack	attack	NOUN
admet-400	149	4	by	by	ADP
admet-400	149	5	a	a	DET
admet-400	149	6	pore	pore	ADV
admet-400	149	7	-	-	PUNCT
admet-400	149	8	forming	form	VERB
admet-400	149	9	intestinal	intestinal	ADJ
admet-400	149	10	c	c	NOUN
admet-400	149	11	-	-	PUNCT
admet-400	149	12	type	type	NOUN
admet-400	149	13	lectin	lectin	NOUN
admet-400	149	14	.	.	PUNCT
admet-400	150	1	nature	nature	NOUN
admet-400	150	2	,	,	PUNCT
admet-400	150	3	505	505	NUM
admet-400	150	4	(	(	PUNCT
admet-400	150	5	2014	2014	NUM
admet-400	150	6	)	)	PUNCT
admet-400	150	7	103–7	103–7	NOUN
admet-400	150	8	.	.	PUNCT
admet-400	151	1	[	[	X
admet-400	151	2	8	8	NUM
admet-400	151	3	]	]	X
admet-400	151	4	d.	d.	PROPN
admet-400	151	5	kahne	kahne	PROPN
admet-400	151	6	,	,	PUNCT
admet-400	151	7	c.	c.	PROPN
admet-400	151	8	leimkuhler	leimkuhler	PROPN
admet-400	151	9	,	,	PUNCT
admet-400	151	10	w.	w.	PROPN
admet-400	151	11	lu	lu	PROPN
admet-400	151	12	,	,	PUNCT
admet-400	151	13	c.	c.	PROPN
admet-400	151	14	walsh	walsh	PROPN
admet-400	151	15	.	.	PUNCT
admet-400	151	16	glycopeptide	glycopeptide	VERB
admet-400	151	17	and	and	CCONJ
admet-400	151	18	lipoglycopeptide	lipoglycopeptide	ADJ
admet-400	151	19	antibiotics	antibiotic	NOUN
admet-400	151	20	.	.	PUNCT
admet-400	152	1	chem	chem	NOUN
admet-400	152	2	.	.	PUNCT
admet-400	153	1	rev	rev	PROPN
admet-400	153	2	.	.	PROPN
admet-400	153	3	,	,	PUNCT
admet-400	153	4	105	105	NUM
admet-400	153	5	(	(	PUNCT
admet-400	153	6	2005	2005	NUM
admet-400	153	7	)	)	PUNCT
admet-400	154	1	425–448	425–448	NUM
admet-400	154	2	.	.	PUNCT
admet-400	155	1	[	[	X
admet-400	155	2	9	9	NUM
admet-400	155	3	]	]	X
admet-400	155	4	d.l	d.l	PROPN
admet-400	155	5	.	.	PROPN
admet-400	155	6	stevens	stevens	PROPN
admet-400	155	7	.	.	PUNCT
admet-400	156	1	the	the	DET
admet-400	156	2	role	role	NOUN
admet-400	156	3	of	of	ADP
admet-400	156	4	vancomycin	vancomycin	PROPN
admet-400	156	5	in	in	ADP
admet-400	156	6	the	the	DET
admet-400	156	7	treatment	treatment	NOUN
admet-400	156	8	paradigm	paradigm	NOUN
admet-400	156	9	.	.	PUNCT
admet-400	157	1	clin	clin	PROPN
admet-400	157	2	.	.	PUNCT
admet-400	158	1	infect	infect	VERB
admet-400	158	2	.	.	PUNCT
admet-400	159	1	dis	dis	PROPN
admet-400	159	2	.	.	PROPN
admet-400	159	3	,	,	PUNCT
admet-400	159	4	42	42	NUM
admet-400	159	5	suppl	suppl	ADJ
admet-400	159	6	1	1	NUM
admet-400	159	7	(	(	PUNCT
admet-400	159	8	2006	2006	NUM
admet-400	159	9	)	)	PUNCT
admet-400	159	10	s51–7	s51–7	NOUN
admet-400	159	11	.	.	PUNCT
admet-400	160	1	[	[	X
admet-400	160	2	10	10	NUM
admet-400	160	3	]	]	X
admet-400	160	4	e.	e.	PROPN
admet-400	160	5	breukink	breukink	PROPN
admet-400	160	6	,	,	PUNCT
admet-400	160	7	b.	b.	PROPN
admet-400	160	8	de	de	X
admet-400	160	9	kruijff	kruijff	PROPN
admet-400	160	10	.	.	PUNCT
admet-400	161	1	lipid	lipid	PROPN
admet-400	161	2	ii	ii	PROPN
admet-400	161	3	as	as	ADP
admet-400	161	4	a	a	DET
admet-400	161	5	target	target	NOUN
admet-400	161	6	for	for	ADP
admet-400	161	7	antibiotics	antibiotic	NOUN
admet-400	161	8	.	.	PUNCT
admet-400	162	1	nat	nat	PROPN
admet-400	162	2	.	.	PUNCT
admet-400	163	1	rev	rev	PROPN
admet-400	163	2	.	.	PROPN
admet-400	163	3	drug	drug	NOUN
admet-400	163	4	discov	discov	PROPN
admet-400	163	5	.	.	PUNCT
admet-400	163	6	,	,	PUNCT
admet-400	163	7	5	5	NUM
admet-400	163	8	(	(	PUNCT
admet-400	163	9	2006	2006	NUM
admet-400	163	10	)	)	PUNCT
admet-400	163	11	321	321	NUM
admet-400	163	12	–	–	PUNCT
admet-400	163	13	332	332	NUM
admet-400	163	14	.	.	PUNCT
admet-400	164	1	[	[	X
admet-400	164	2	11	11	NUM
admet-400	164	3	]	]	X
admet-400	164	4	u.s	u.s	PROPN
admet-400	164	5	.	.	PROPN
admet-400	164	6	eggert	eggert	PROPN
admet-400	164	7	,	,	PUNCT
admet-400	164	8	n.	n.	PROPN
admet-400	164	9	ruiz	ruiz	PROPN
admet-400	164	10	,	,	PUNCT
admet-400	164	11	b.	b.	PROPN
admet-400	164	12	v	v	PROPN
admet-400	164	13	falcone	falcone	PROPN
admet-400	164	14	,	,	PUNCT
admet-400	164	15	a.a	a.a	PROPN
admet-400	164	16	.	.	PROPN
admet-400	164	17	branstrom	branstrom	PROPN
admet-400	164	18	,	,	PUNCT
admet-400	164	19	r.c	r.c	PROPN
admet-400	164	20	.	.	PROPN
admet-400	164	21	goldman	goldman	PROPN
admet-400	164	22	,	,	PUNCT
admet-400	164	23	t.j	t.j	PROPN
admet-400	164	24	.	.	PROPN
admet-400	164	25	silhavy	silhavy	PROPN
admet-400	164	26	,	,	PUNCT
admet-400	164	27	d.	d.	PROPN
admet-400	164	28	kahne	kahne	PROPN
admet-400	164	29	.	.	PUNCT
admet-400	165	1	genetic	genetic	ADJ
admet-400	165	2	basis	basis	NOUN
admet-400	165	3	for	for	ADP
admet-400	165	4	activity	activity	NOUN
admet-400	165	5	differences	difference	NOUN
admet-400	165	6	between	between	ADP
admet-400	165	7	vancomycin	vancomycin	PROPN
admet-400	165	8	and	and	CCONJ
admet-400	165	9	glycolipid	glycolipid	ADJ
admet-400	165	10	derivatives	derivative	NOUN
admet-400	165	11	of	of	ADP
admet-400	165	12	vancomycin	vancomycin	PROPN
admet-400	165	13	.	.	PUNCT
admet-400	166	1	science	science	PROPN
admet-400	166	2	,	,	PUNCT
admet-400	166	3	294	294	NUM
admet-400	166	4	(	(	PUNCT
admet-400	166	5	2001	2001	NUM
admet-400	166	6	)	)	PUNCT
admet-400	166	7	361–364	361–364	NUM
admet-400	166	8	.	.	PUNCT
admet-400	167	1	[	[	X
admet-400	167	2	12	12	NUM
admet-400	167	3	]	]	X
admet-400	167	4	g.d	g.d	PROPN
admet-400	167	5	.	.	PROPN
admet-400	167	6	wright	wright	PROPN
admet-400	167	7	,	,	PUNCT
admet-400	167	8	c.t	c.t	PROPN
admet-400	167	9	.	.	PROPN
admet-400	167	10	walsh	walsh	PROPN
admet-400	167	11	.	.	PUNCT
admet-400	168	1	d	d	X
admet-400	168	2	-	-	PUNCT
admet-400	168	3	alanyl	alanyl	VERB
admet-400	168	4	-	-	PUNCT
admet-400	168	5	d	d	NOUN
admet-400	168	6	-	-	PUNCT
admet-400	168	7	alanine	alanine	NOUN
admet-400	168	8	ligases	ligase	NOUN
admet-400	168	9	and	and	CCONJ
admet-400	168	10	the	the	DET
admet-400	168	11	molecular	molecular	ADJ
admet-400	168	12	mechanism	mechanism	NOUN
admet-400	168	13	of	of	ADP
admet-400	168	14	vancomycin	vancomycin	PROPN
admet-400	168	15	resistance	resistance	PROPN
admet-400	168	16	.	.	PUNCT
admet-400	169	1	acc	acc	PROPN
admet-400	169	2	.	.	PROPN
admet-400	169	3	chem	chem	PROPN
admet-400	169	4	.	.	PUNCT
admet-400	170	1	res	re	NOUN
admet-400	170	2	.	.	PROPN
admet-400	170	3	,	,	PUNCT
admet-400	170	4	25	25	NUM
admet-400	170	5	(	(	PUNCT
admet-400	170	6	1992	1992	NUM
admet-400	170	7	)	)	PUNCT
admet-400	170	8	468–473	468–473	NUM
admet-400	170	9	.	.	PUNCT
admet-400	171	1	[	[	X
admet-400	171	2	13	13	NUM
admet-400	171	3	]	]	PUNCT
admet-400	171	4	l.	l.	PROPN
admet-400	171	5	otvos	otvos	PROPN
admet-400	171	6	,	,	PUNCT
admet-400	171	7	c.	c.	PROPN
admet-400	171	8	snyder	snyder	PROPN
admet-400	171	9	,	,	PUNCT
admet-400	171	10	b.	b.	PROPN
admet-400	171	11	condie	condie	PROPN
admet-400	171	12	,	,	PUNCT
admet-400	171	13	p.	p.	NOUN
admet-400	171	14	bulet	bulet	NOUN
admet-400	171	15	,	,	PUNCT
admet-400	171	16	j.d	j.d	PROPN
admet-400	171	17	.	.	PROPN
admet-400	171	18	wade	wade	PROPN
admet-400	171	19	.	.	PUNCT
admet-400	172	1	chimeric	chimeric	ADJ
admet-400	172	2	antimicrobial	antimicrobial	ADJ
admet-400	172	3	peptides	peptide	NOUN
admet-400	172	4	exhibit	exhibit	VERB
admet-400	172	5	multiple	multiple	ADJ
admet-400	172	6	modes	mode	NOUN
admet-400	172	7	of	of	ADP
admet-400	172	8	action	action	NOUN
admet-400	172	9	.	.	PUNCT
admet-400	173	1	int	int	NOUN
admet-400	173	2	.	.	PUNCT
admet-400	174	1	j.	j.	PROPN
admet-400	174	2	pept	pept	PROPN
admet-400	174	3	.	.	PUNCT
admet-400	175	1	res	re	NOUN
admet-400	175	2	.	.	PUNCT
admet-400	176	1	ther	ther	PROPN
admet-400	176	2	.	.	PUNCT
admet-400	177	1	,	,	PUNCT
admet-400	177	2	11	11	NUM
admet-400	177	3	(	(	PUNCT
admet-400	177	4	2005	2005	NUM
admet-400	177	5	)	)	PUNCT
admet-400	178	1	29–42	29–42	NUM
admet-400	178	2	.	.	PUNCT
admet-400	179	1	[	[	X
admet-400	179	2	14	14	NUM
admet-400	179	3	]	]	X
admet-400	179	4	v.	v.	CCONJ
admet-400	179	5	yarlagadda	yarlagadda	PROPN
admet-400	179	6	,	,	PUNCT
admet-400	179	7	s.	s.	PROPN
admet-400	179	8	samaddar	samaddar	PROPN
admet-400	179	9	,	,	PUNCT
admet-400	179	10	k.	k.	PROPN
admet-400	179	11	paramanandham	paramanandham	PROPN
admet-400	179	12	,	,	PUNCT
admet-400	179	13	b.r	b.r	PROPN
admet-400	179	14	.	.	PROPN
admet-400	179	15	shome	shome	PROPN
admet-400	179	16	,	,	PUNCT
admet-400	179	17	j.	j.	PROPN
admet-400	179	18	haldar	haldar	PROPN
admet-400	179	19	.	.	PUNCT
admet-400	180	1	membrane	membrane	NOUN
admet-400	180	2	disruption	disruption	NOUN
admet-400	180	3	and	and	CCONJ
admet-400	180	4	enhanced	enhance	VERB
admet-400	180	5	inhibition	inhibition	NOUN
admet-400	180	6	of	of	ADP
admet-400	180	7	cell	cell	NOUN
admet-400	180	8	-	-	PUNCT
admet-400	180	9	wall	wall	NOUN
admet-400	180	10	biosynthesis	biosynthesis	NOUN
admet-400	180	11	:	:	PUNCT
admet-400	180	12	a	a	DET
admet-400	180	13	synergistic	synergistic	ADJ
admet-400	180	14	approach	approach	NOUN
admet-400	180	15	to	to	PART
admet-400	180	16	tackle	tackle	VERB
admet-400	180	17	vancomycinresistant	vancomycinresistant	ADJ
admet-400	180	18	bacteria	bacteria	NOUN
admet-400	180	19	.	.	PUNCT
admet-400	181	1	angew	angew	PROPN
admet-400	181	2	.	.	PUNCT
admet-400	182	1	chem	chem	PROPN
admet-400	182	2	.	.	PUNCT
admet-400	183	1	int	int	NOUN
admet-400	183	2	.	.	PUNCT
admet-400	184	1	ed	ed	NOUN
admet-400	184	2	.	.	PUNCT
admet-400	184	3	engl	engl	PROPN
admet-400	184	4	.	.	PROPN
admet-400	184	5	,	,	PUNCT
admet-400	184	6	54	54	NUM
admet-400	184	7	(	(	PUNCT
admet-400	184	8	2015	2015	NUM
admet-400	184	9	)	)	PUNCT
admet-400	184	10	13644–13649	13644–13649	NUM
admet-400	184	11	.	.	PUNCT
admet-400	185	1	[	[	X
admet-400	185	2	15	15	NUM
admet-400	185	3	]	]	X
admet-400	185	4	f.	f.	PROPN
admet-400	185	5	guilhelmelli	guilhelmelli	PROPN
admet-400	185	6	,	,	PUNCT
admet-400	185	7	n.	n.	PROPN
admet-400	185	8	vilela	vilela	PROPN
admet-400	185	9	,	,	PUNCT
admet-400	185	10	p.	p.	PROPN
admet-400	185	11	albuquerque	albuquerque	PROPN
admet-400	185	12	,	,	PUNCT
admet-400	185	13	l.	l.	PROPN
admet-400	185	14	da	da	PROPN
admet-400	185	15	s.	s.	PROPN
admet-400	185	16	derengowski	derengowski	PROPN
admet-400	185	17	,	,	PUNCT
admet-400	186	1	i.	i.	PROPN
admet-400	186	2	silva	silva	PROPN
admet-400	186	3	-	-	PUNCT
admet-400	186	4	pereira	pereira	PROPN
admet-400	186	5	,	,	PUNCT
admet-400	186	6	c.m	c.m	PROPN
admet-400	186	7	.	.	PUNCT
admet-400	186	8	kyaw	kyaw	PROPN
admet-400	186	9	.	.	PUNCT
admet-400	187	1	antibiotic	antibiotic	ADJ
admet-400	187	2	development	development	NOUN
admet-400	187	3	challenges	challenge	NOUN
admet-400	187	4	:	:	PUNCT
admet-400	187	5	the	the	DET
admet-400	187	6	various	various	ADJ
admet-400	187	7	mechanisms	mechanism	NOUN
admet-400	187	8	of	of	ADP
admet-400	187	9	action	action	NOUN
admet-400	187	10	of	of	ADP
admet-400	187	11	antimicrobial	antimicrobial	ADJ
admet-400	187	12	peptides	peptide	NOUN
admet-400	187	13	and	and	CCONJ
admet-400	187	14	of	of	ADP
admet-400	187	15	bacterial	bacterial	ADJ
admet-400	187	16	resistance	resistance	NOUN
admet-400	187	17	.	.	PUNCT
admet-400	188	1	front	front	ADJ
admet-400	188	2	.	.	PUNCT
admet-400	189	1	microbiol	microbiol	PROPN
admet-400	189	2	.	.	PUNCT
admet-400	190	1	,	,	PUNCT
admet-400	190	2	4	4	NUM
admet-400	190	3	(	(	PUNCT
admet-400	190	4	2013	2013	NUM
admet-400	190	5	)	)	PUNCT
admet-400	190	6	353	353	NUM
admet-400	190	7	.	.	PUNCT
admet-400	191	1	[	[	X
admet-400	191	2	16	16	NUM
admet-400	191	3	]	]	X
admet-400	191	4	r.k	r.k	PROPN
admet-400	191	5	.	.	PROPN
admet-400	191	6	poole	poole	PROPN
admet-400	191	7	.	.	PUNCT
admet-400	192	1	the	the	DET
admet-400	192	2	isolation	isolation	NOUN
admet-400	192	3	of	of	ADP
admet-400	192	4	membranes	membrane	NOUN
admet-400	192	5	from	from	ADP
admet-400	192	6	bacteria	bacteria	NOUN
admet-400	192	7	.	.	PUNCT
admet-400	193	1	methods	method	NOUN
admet-400	193	2	mol	mol	PROPN
admet-400	193	3	.	.	PUNCT
admet-400	194	1	biol	biol	PROPN
admet-400	194	2	.	.	PUNCT
admet-400	194	3	,	,	PUNCT
admet-400	194	4	19	19	NUM
admet-400	194	5	(	(	PUNCT
admet-400	194	6	1993	1993	NUM
admet-400	194	7	)	)	PUNCT
admet-400	194	8	109–122	109–122	NUM
admet-400	194	9	.	.	PUNCT
admet-400	195	1	[	[	X
admet-400	195	2	17	17	NUM
admet-400	195	3	]	]	X
admet-400	195	4	j.k.l	j.k.l	NOUN
admet-400	195	5	.	.	PROPN
admet-400	195	6	and	and	CCONJ
admet-400	195	7	e.j.p	e.j.p	PROPN
admet-400	195	8	.	.	PUNCT
admet-400	196	1	mary	mary	PROPN
admet-400	196	2	t.	t.	PROPN
admet-400	196	3	le	le	PROPN
admet-400	196	4	.	.	PUNCT
admet-400	197	1	biomimetic	biomimetic	ADJ
admet-400	197	2	model	model	NOUN
admet-400	197	3	membrane	membrane	NOUN
admet-400	197	4	systems	system	NOUN
admet-400	197	5	serve	serve	VERB
admet-400	197	6	as	as	ADV
admet-400	197	7	increasingly	increasingly	ADV
admet-400	197	8	valuable	valuable	ADJ
admet-400	197	9	in	in	ADP
admet-400	197	10	vitro	vitro	X
admet-400	197	11	tools	tool	NOUN
admet-400	197	12	.	.	PUNCT
admet-400	198	1	in	in	ADP
admet-400	198	2	:	:	PUNCT
admet-400	198	3	a.	a.	PROPN
admet-400	198	4	george	george	PROPN
admet-400	198	5	(	(	PUNCT
admet-400	198	6	ed	ed	NOUN
admet-400	198	7	.	.	PUNCT
admet-400	198	8	)	)	PUNCT
admet-400	198	9	,	,	PUNCT
admet-400	198	10	adv	adv	PROPN
admet-400	198	11	.	.	PUNCT
admet-400	198	12	biomimetics	biomimetics	PROPN
admet-400	198	13	,	,	PUNCT
admet-400	198	14	intech	intech	PROPN
admet-400	198	15	,	,	PUNCT
admet-400	198	16	2011	2011	NUM
admet-400	198	17	.	.	PUNCT
admet-400	199	1	[	[	X
admet-400	199	2	18	18	NUM
admet-400	199	3	]	]	PUNCT
admet-400	199	4	s.	s.	PROPN
admet-400	199	5	al	al	PROPN
admet-400	199	6	-	-	PUNCT
admet-400	199	7	kaddah	kaddah	PROPN
admet-400	199	8	,	,	PUNCT
admet-400	199	9	k.	k.	PROPN
admet-400	199	10	reder	reder	PROPN
admet-400	199	11	-	-	PUNCT
admet-400	199	12	christ	christ	PROPN
admet-400	199	13	,	,	PUNCT
admet-400	199	14	g.	g.	PROPN
admet-400	199	15	klocek	klocek	PROPN
admet-400	199	16	,	,	PUNCT
admet-400	199	17	i.	i.	PROPN
admet-400	199	18	wiedemann	wiedemann	PROPN
admet-400	199	19	,	,	PUNCT
admet-400	199	20	m.	m.	NOUN
admet-400	199	21	brunschweiger	brunschweiger	NOUN
admet-400	199	22	,	,	PUNCT
admet-400	199	23	g.	g.	PROPN
admet-400	199	24	bendas	bendas	PROPN
admet-400	199	25	.	.	PUNCT
admet-400	200	1	analysis	analysis	NOUN
admet-400	200	2	of	of	ADP
admet-400	200	3	membrane	membrane	NOUN
admet-400	200	4	interactions	interaction	NOUN
admet-400	200	5	of	of	ADP
admet-400	200	6	antibiotic	antibiotic	ADJ
admet-400	200	7	peptides	peptide	NOUN
admet-400	200	8	using	use	VERB
admet-400	200	9	itc	itc	PROPN
admet-400	200	10	and	and	CCONJ
admet-400	200	11	biosensor	biosensor	NOUN
admet-400	200	12	measurements	measurement	NOUN
admet-400	200	13	.	.	PUNCT
admet-400	201	1	biophys	biophy	NOUN
admet-400	201	2	.	.	PUNCT
admet-400	202	1	chem	chem	NOUN
admet-400	202	2	.	.	PUNCT
admet-400	202	3	,	,	PUNCT
admet-400	202	4	152	152	NUM
admet-400	202	5	(	(	PUNCT
admet-400	202	6	2010	2010	NUM
admet-400	202	7	)	)	PUNCT
admet-400	203	1	145–152	145–152	NUM
admet-400	203	2	.	.	PUNCT
admet-400	204	1	[	[	X
admet-400	204	2	19	19	NUM
admet-400	204	3	]	]	X
admet-400	204	4	h.	h.	PROPN
admet-400	204	5	kinouchi	kinouchi	PROPN
admet-400	204	6	,	,	PUNCT
admet-400	204	7	h.	h.	PROPN
admet-400	204	8	arimoto	arimoto	PROPN
admet-400	204	9	,	,	PUNCT
admet-400	204	10	k.	k.	PROPN
admet-400	204	11	nishiguchi	nishiguchi	PROPN
admet-400	204	12	,	,	PUNCT
admet-400	204	13	m.	m.	NOUN
admet-400	204	14	oka	oka	PROPN
admet-400	204	15	,	,	PUNCT
admet-400	204	16	h.	h.	PROPN
admet-400	204	17	maki	maki	PROPN
admet-400	204	18	,	,	PUNCT
admet-400	204	19	h.	h.	PROPN
admet-400	204	20	kitagawa	kitagawa	PROPN
admet-400	204	21	,	,	PUNCT
admet-400	204	22	h.	h.	PROPN
admet-400	204	23	kamimori	kamimori	PROPN
admet-400	204	24	.	.	PUNCT
admet-400	205	1	binding	bind	VERB
admet-400	205	2	properties	property	NOUN
admet-400	205	3	of	of	ADP
admet-400	205	4	antimicrobial	antimicrobial	ADJ
admet-400	205	5	agents	agent	NOUN
admet-400	205	6	to	to	ADP
admet-400	205	7	lipid	lipid	NOUN
admet-400	205	8	membranes	membrane	NOUN
admet-400	205	9	using	use	VERB
admet-400	205	10	surface	surface	NOUN
admet-400	205	11	plasmon	plasmon	ADJ
admet-400	205	12	resonance	resonance	NOUN
admet-400	205	13	.	.	PUNCT
admet-400	206	1	biol	biol	PROPN
admet-400	206	2	.	.	PUNCT
admet-400	207	1	pharm	pharm	PROPN
admet-400	207	2	.	.	PUNCT
admet-400	208	1	bull	bull	PROPN
admet-400	208	2	.	.	PUNCT
admet-400	209	1	,	,	PUNCT
admet-400	209	2	37	37	NUM
admet-400	209	3	(	(	PUNCT
admet-400	209	4	2014	2014	NUM
admet-400	209	5	)	)	PUNCT
admet-400	209	6	1383–1389	1383–1389	NUM
admet-400	209	7	.	.	PUNCT
admet-400	210	1	[	[	X
admet-400	210	2	20	20	NUM
admet-400	210	3	]	]	PUNCT
admet-400	210	4	z.	z.	PROPN
admet-400	210	5	jia	jia	PROPN
admet-400	210	6	,	,	PUNCT
admet-400	210	7	m.l	m.l	PROPN
admet-400	210	8	.	.	PROPN
admet-400	210	9	o’mara	o’mara	PROPN
admet-400	210	10	,	,	PUNCT
admet-400	210	11	j.	j.	PROPN
admet-400	210	12	zuegg	zuegg	PROPN
admet-400	210	13	,	,	PUNCT
admet-400	210	14	m.a	m.a	PROPN
admet-400	210	15	.	.	PROPN
admet-400	210	16	cooper	cooper	PROPN
admet-400	210	17	,	,	PUNCT
admet-400	210	18	a.e	a.e	PROPN
admet-400	210	19	.	.	PROPN
admet-400	210	20	mark	mark	PROPN
admet-400	210	21	.	.	PUNCT
admet-400	211	1	vancomycin	vancomycin	PROPN
admet-400	211	2	:	:	PUNCT
admet-400	211	3	ligand	ligand	NOUN
admet-400	211	4	recognition	recognition	NOUN
admet-400	211	5	,	,	PUNCT
admet-400	211	6	dimerization	dimerization	NOUN
admet-400	211	7	and	and	CCONJ
admet-400	211	8	super	super	ADJ
admet-400	211	9	-	-	ADJ
admet-400	211	10	complex	complex	ADJ
admet-400	211	11	formation	formation	NOUN
admet-400	211	12	.	.	PUNCT
admet-400	212	1	febs	febs	PROPN
admet-400	212	2	j.	j.	PROPN
admet-400	212	3	,	,	PUNCT
admet-400	212	4	280	280	NUM
admet-400	212	5	(	(	PUNCT
admet-400	212	6	2013	2013	NUM
admet-400	212	7	)	)	PUNCT
admet-400	212	8	1294–1307	1294–1307	NUM
admet-400	212	9	.	.	PUNCT
admet-400	213	1	admet	admet	PROPN
admet-400	213	2	&	&	CCONJ
admet-400	213	3	dmpk	dmpk	PROPN
admet-400	213	4	5(3	5(3	NUM
admet-400	213	5	)	)	PUNCT
admet-400	213	6	(	(	PUNCT
admet-400	213	7	2017	2017	NUM
admet-400	213	8	)	)	PUNCT
admet-400	213	9	183	183	NUM
admet-400	213	10	-	-	SYM
admet-400	213	11	191	191	NUM
admet-400	213	12	association	association	NOUN
admet-400	213	13	of	of	ADP
admet-400	213	14	vancomycin	vancomycin	PROPN
admet-400	213	15	with	with	ADP
admet-400	213	16	lipid	lipid	NOUN
admet-400	213	17	vesicles	vesicle	NOUN
admet-400	213	18	doi	doi	NOUN
admet-400	213	19	:	:	PUNCT
admet-400	213	20	10.5599	10.5599	NUM
admet-400	213	21	/	/	SYM
admet-400	213	22	admet.5.3.400	admet.5.3.400	NOUN
admet-400	213	23	191	191	NUM
admet-400	213	24	[	[	X
admet-400	213	25	21	21	NUM
admet-400	213	26	]	]	X
admet-400	213	27	p.j	p.j	PROPN
admet-400	213	28	.	.	PROPN
admet-400	213	29	loll	loll	PROPN
admet-400	213	30	,	,	PUNCT
admet-400	213	31	a.e	a.e	PROPN
admet-400	213	32	.	.	PROPN
admet-400	213	33	bevivino	bevivino	PROPN
admet-400	213	34	,	,	PUNCT
admet-400	213	35	b.d	b.d	PROPN
admet-400	213	36	.	.	PROPN
admet-400	213	37	korty	korty	PROPN
admet-400	213	38	,	,	PUNCT
admet-400	213	39	p.h	p.h	PROPN
admet-400	213	40	.	.	PROPN
admet-400	213	41	axelsen	axelsen	PROPN
admet-400	213	42	.	.	PUNCT
admet-400	214	1	simultaneous	simultaneous	ADJ
admet-400	214	2	recognition	recognition	NOUN
admet-400	214	3	of	of	ADP
admet-400	214	4	a	a	DET
admet-400	214	5	carboxylatecontaining	carboxylatecontaine	VERB
admet-400	214	6	ligand	ligand	NOUN
admet-400	214	7	and	and	CCONJ
admet-400	214	8	an	an	DET
admet-400	214	9	intramolecular	intramolecular	ADJ
admet-400	214	10	surrogate	surrogate	ADJ
admet-400	214	11	ligand	ligand	NOUN
admet-400	214	12	in	in	ADP
admet-400	214	13	the	the	DET
admet-400	214	14	crystal	crystal	NOUN
admet-400	214	15	structure	structure	NOUN
admet-400	214	16	of	of	ADP
admet-400	214	17	an	an	DET
admet-400	214	18	asymmetric	asymmetric	ADJ
admet-400	214	19	vancomycin	vancomycin	PROPN
admet-400	214	20	dimer	dimer	NOUN
admet-400	214	21	.	.	PUNCT
admet-400	215	1	j.	j.	PROPN
admet-400	215	2	am	am	PROPN
admet-400	215	3	.	.	PUNCT
admet-400	216	1	chem	chem	NOUN
admet-400	216	2	.	.	PUNCT
admet-400	217	1	soc	soc	PROPN
admet-400	217	2	.	.	PUNCT
admet-400	217	3	,	,	PUNCT
admet-400	217	4	119	119	NUM
admet-400	217	5	(	(	PUNCT
admet-400	217	6	1997	1997	NUM
admet-400	217	7	)	)	PUNCT
admet-400	217	8	1516–1522	1516–1522	NUM
admet-400	217	9	.	.	PUNCT
admet-400	218	1	[	[	X
admet-400	218	2	22	22	NUM
admet-400	218	3	]	]	X
admet-400	218	4	o.	o.	PROPN
admet-400	218	5	domenech	domenech	PROPN
admet-400	218	6	,	,	PUNCT
admet-400	218	7	g.	g.	PROPN
admet-400	218	8	francius	francius	PROPN
admet-400	218	9	,	,	PUNCT
admet-400	218	10	p.m.	p.m.	NOUN
admet-400	218	11	tulkens	tulkens	PROPN
admet-400	218	12	,	,	PUNCT
admet-400	218	13	f.	f.	PROPN
admet-400	218	14	van	van	PROPN
admet-400	218	15	bambeke	bambeke	PROPN
admet-400	218	16	,	,	PUNCT
admet-400	218	17	y.	y.	PROPN
admet-400	218	18	dufrêne	dufrêne	PROPN
admet-400	218	19	,	,	PUNCT
admet-400	218	20	m.-p	m.-p	PROPN
admet-400	218	21	.	.	PUNCT
admet-400	219	1	mingeot	mingeot	PROPN
admet-400	219	2	-	-	PUNCT
admet-400	219	3	leclercq	leclercq	NOUN
admet-400	219	4	.	.	PUNCT
admet-400	220	1	interactions	interaction	NOUN
admet-400	220	2	of	of	ADP
admet-400	220	3	oritavancin	oritavancin	NOUN
admet-400	220	4	,	,	PUNCT
admet-400	220	5	a	a	DET
admet-400	220	6	new	new	ADJ
admet-400	220	7	lipoglycopeptide	lipoglycopeptide	NOUN
admet-400	220	8	derived	derive	VERB
admet-400	220	9	from	from	ADP
admet-400	220	10	vancomycin	vancomycin	PROPN
admet-400	220	11	,	,	PUNCT
admet-400	220	12	with	with	ADP
admet-400	220	13	phospholipid	phospholipid	NOUN
admet-400	220	14	bilayers	bilayer	NOUN
admet-400	220	15	:	:	PUNCT
admet-400	220	16	effect	effect	NOUN
admet-400	220	17	on	on	ADP
admet-400	220	18	membrane	membrane	NOUN
admet-400	220	19	permeability	permeability	NOUN
admet-400	220	20	and	and	CCONJ
admet-400	220	21	nanoscale	nanoscale	NOUN
admet-400	220	22	lipid	lipid	NOUN
admet-400	220	23	membrane	membrane	NOUN
admet-400	220	24	organization	organization	NOUN
admet-400	220	25	.	.	PUNCT
admet-400	221	1	biochim	biochim	PROPN
admet-400	221	2	.	.	PUNCT
admet-400	222	1	biophys	biophy	NOUN
admet-400	222	2	.	.	PUNCT
admet-400	223	1	acta	acta	PROPN
admet-400	223	2	biomembr	biomembr	PROPN
admet-400	223	3	.	.	PUNCT
admet-400	223	4	,	,	PUNCT
admet-400	223	5	1788	1788	NUM
admet-400	223	6	(	(	PUNCT
admet-400	223	7	2009	2009	NUM
admet-400	223	8	)	)	PUNCT
admet-400	223	9	1832–1840	1832–1840	NUM
admet-400	223	10	.	.	PUNCT
admet-400	224	1	[	[	X
admet-400	224	2	23	23	NUM
admet-400	224	3	]	]	X
admet-400	224	4	t.e	t.e	PROPN
admet-400	224	5	.	.	PROPN
admet-400	224	6	andreoli	andreoli	PROPN
admet-400	224	7	.	.	PUNCT
admet-400	225	1	the	the	DET
admet-400	225	2	effect	effect	NOUN
admet-400	225	3	of	of	ADP
admet-400	225	4	valinomycin	valinomycin	NOUN
admet-400	225	5	on	on	ADP
admet-400	225	6	the	the	DET
admet-400	225	7	ionic	ionic	ADJ
admet-400	225	8	permeability	permeability	NOUN
admet-400	225	9	of	of	ADP
admet-400	225	10	thin	thin	ADJ
admet-400	225	11	lipid	lipid	NOUN
admet-400	225	12	membranes	membrane	NOUN
admet-400	225	13	.	.	PUNCT
admet-400	226	1	j.	j.	PROPN
admet-400	226	2	gen	gen	PROPN
admet-400	226	3	.	.	PROPN
admet-400	226	4	physiol	physiol	PROPN
admet-400	226	5	.	.	PUNCT
admet-400	227	1	,	,	PUNCT
admet-400	227	2	50	50	NUM
admet-400	227	3	(	(	PUNCT
admet-400	227	4	1967	1967	NUM
admet-400	227	5	)	)	PUNCT
admet-400	227	6	2527–2545	2527–2545	NUM
admet-400	227	7	.	.	PUNCT
admet-400	228	1	[	[	X
admet-400	228	2	24	24	NUM
admet-400	228	3	]	]	PUNCT
admet-400	228	4	p.	p.	NOUN
admet-400	228	5	bhattacharyya	bhattacharyya	PROPN
admet-400	228	6	,	,	PUNCT
admet-400	228	7	w.	w.	PROPN
admet-400	228	8	epstein	epstein	PROPN
admet-400	228	9	,	,	PUNCT
admet-400	228	10	s.	s.	PROPN
admet-400	228	11	silver	silver	PROPN
admet-400	228	12	.	.	PUNCT
admet-400	229	1	valinomycin	valinomycin	PROPN
admet-400	229	2	-	-	PUNCT
admet-400	229	3	induced	induce	VERB
admet-400	229	4	uptake	uptake	NOUN
admet-400	229	5	of	of	ADP
admet-400	229	6	potassium	potassium	NOUN
admet-400	229	7	in	in	ADP
admet-400	229	8	membrane	membrane	NOUN
admet-400	229	9	vesicles	vesicle	NOUN
admet-400	229	10	from	from	ADP
admet-400	229	11	escherichia	escherichia	NOUN
admet-400	229	12	coli	coli	NOUN
admet-400	229	13	.	.	PUNCT
admet-400	230	1	proc	proc	PROPN
admet-400	230	2	.	.	PUNCT
admet-400	231	1	natl	natl	PROPN
admet-400	231	2	.	.	PUNCT
admet-400	232	1	acad	acad	PROPN
admet-400	232	2	.	.	PUNCT
admet-400	233	1	sci	sci	PROPN
admet-400	233	2	.	.	PROPN
admet-400	233	3	,	,	PUNCT
admet-400	233	4	68	68	NUM
admet-400	233	5	(	(	PUNCT
admet-400	233	6	1971	1971	NUM
admet-400	233	7	)	)	PUNCT
admet-400	233	8	1488–1492	1488–1492	NUM
admet-400	233	9	.	.	PUNCT
admet-400	234	1	[	[	X
admet-400	234	2	25	25	NUM
admet-400	234	3	]	]	X
admet-400	234	4	s.	s.	PROPN
admet-400	234	5	gardete	gardete	PROPN
admet-400	234	6	,	,	PUNCT
admet-400	234	7	a.	a.	PROPN
admet-400	234	8	tomasz	tomasz	PROPN
admet-400	234	9	.	.	PUNCT
admet-400	235	1	mechanisms	mechanism	NOUN
admet-400	235	2	of	of	ADP
admet-400	235	3	vancomycin	vancomycin	PROPN
admet-400	235	4	resistance	resistance	NOUN
admet-400	235	5	in	in	ADP
admet-400	235	6	staphylococcus	staphylococcus	NOUN
admet-400	235	7	aureus	aureus	NOUN
admet-400	235	8	.	.	PUNCT
admet-400	236	1	j.	j.	PROPN
admet-400	236	2	clin	clin	PROPN
admet-400	236	3	.	.	PUNCT
admet-400	237	1	invest	invest	PROPN
admet-400	237	2	.	.	PUNCT
admet-400	238	1	,	,	PUNCT
admet-400	238	2	124	124	NUM
admet-400	238	3	(	(	PUNCT
admet-400	238	4	2014	2014	NUM
admet-400	238	5	)	)	PUNCT
admet-400	238	6	2836–2840	2836–2840	NUM
admet-400	238	7	.	.	PUNCT
admet-400	239	1	[	[	X
admet-400	239	2	26	26	NUM
admet-400	239	3	]	]	PUNCT
admet-400	239	4	d.mcphail	d.mcphail	PROPN
admet-400	239	5	,	,	PUNCT
admet-400	239	6	a.	a.	PROPN
admet-400	239	7	cooper	cooper	PROPN
admet-400	239	8	,	,	PUNCT
admet-400	239	9	s.	s.	PROPN
admet-400	239	10	j.	j.	PROPN
admet-400	239	11	hammond	hammond	PROPN
admet-400	239	12	,	,	PUNCT
admet-400	239	13	j.	j.	PROPN
admet-400	239	14	p.	p.	PROPN
admet-400	239	15	mackay	mackay	PROPN
admet-400	239	16	,	,	PUNCT
admet-400	239	17	m.	m.	PROPN
admet-400	239	18	s.	s.	PROPN
admet-400	239	19	westwell	westwell	PROPN
admet-400	239	20	,	,	PUNCT
admet-400	239	21	d.	d.	PROPN
admet-400	239	22	a.	a.	PROPN
admet-400	239	23	beauregard	beauregard	PROPN
admet-400	239	24	,	,	PUNCT
admet-400	239	25	m.	m.	PROPN
admet-400	239	26	f.	f.	PROPN
admet-400	239	27	cristofaro	cristofaro	PROPN
admet-400	239	28	.	.	PUNCT
admet-400	240	1	thermodynamics	thermodynamic	NOUN
admet-400	240	2	and	and	CCONJ
admet-400	240	3	kinetics	kinetic	NOUN
admet-400	240	4	of	of	ADP
admet-400	240	5	dissociation	dissociation	NOUN
admet-400	240	6	of	of	ADP
admet-400	240	7	ligand	ligand	NOUN
admet-400	240	8	-	-	PUNCT
admet-400	240	9	induced	induce	VERB
admet-400	240	10	dimers	dimer	NOUN
admet-400	240	11	of	of	ADP
admet-400	240	12	vancomycin	vancomycin	PROPN
admet-400	240	13	antibiotics	antibiotic	NOUN
admet-400	240	14	.	.	PUNCT
admet-400	241	1	j.	j.	PROPN
admet-400	241	2	chem	chem	PROPN
admet-400	241	3	.	.	PUNCT
admet-400	242	1	soc	soc	PROPN
admet-400	242	2	.	.	PUNCT
admet-400	243	1	faraday	faraday	PROPN
admet-400	243	2	trans	trans	PROPN
admet-400	243	3	.	.	PROPN
admet-400	244	1	93	93	NUM
admet-400	244	2	(	(	PUNCT
admet-400	244	3	1997	1997	NUM
admet-400	244	4	)	)	PUNCT
admet-400	244	5	2283–2289	2283–2289	NUM
admet-400	244	6	.	.	PUNCT
admet-400	245	1	[	[	X
admet-400	245	2	27	27	NUM
admet-400	245	3	]	]	PUNCT
admet-400	245	4	m.	m.	NOUN
admet-400	245	5	rekharsky	rekharsky	PROPN
admet-400	245	6	,	,	PUNCT
admet-400	245	7	d.	d.	PROPN
admet-400	245	8	hesek	hesek	PROPN
admet-400	245	9	,	,	PUNCT
admet-400	245	10	m.	m.	PROPN
admet-400	245	11	lee	lee	PROPN
admet-400	245	12	,	,	PUNCT
admet-400	245	13	s.o	s.o	PROPN
admet-400	245	14	.	.	PROPN
admet-400	245	15	meroueh	meroueh	PROPN
admet-400	245	16	,	,	PUNCT
admet-400	245	17	y.	y.	PROPN
admet-400	245	18	inoue	inoue	PROPN
admet-400	245	19	,	,	PUNCT
admet-400	245	20	s.	s.	PROPN
admet-400	245	21	mobashery	mobashery	NOUN
admet-400	245	22	.	.	PUNCT
admet-400	246	1	thermodynamics	thermodynamic	NOUN
admet-400	246	2	of	of	ADP
admet-400	246	3	interactions	interaction	NOUN
admet-400	246	4	of	of	ADP
admet-400	246	5	vancomycin	vancomycin	PROPN
admet-400	246	6	and	and	CCONJ
admet-400	246	7	synthetic	synthetic	ADJ
admet-400	246	8	surrogates	surrogate	NOUN
admet-400	246	9	of	of	ADP
admet-400	246	10	bacterial	bacterial	ADJ
admet-400	246	11	cell	cell	NOUN
admet-400	246	12	wall	wall	NOUN
admet-400	246	13	.	.	PUNCT
admet-400	247	1	j.	j.	PROPN
admet-400	247	2	am	am	PROPN
admet-400	247	3	.	.	PUNCT
admet-400	248	1	chem	chem	NOUN
admet-400	248	2	.	.	PUNCT
admet-400	249	1	soc	soc	PROPN
admet-400	249	2	.	.	PUNCT
admet-400	250	1	128	128	NUM
admet-400	250	2	(	(	PUNCT
admet-400	250	3	2006	2006	NUM
admet-400	250	4	)	)	PUNCT
admet-400	250	5	7736–7737	7736–7737	NUM
admet-400	250	6	.	.	PUNCT
admet-400	251	1	©	©	NOUN
admet-400	251	2	2017	2017	NUM
admet-400	251	3	by	by	ADP
admet-400	251	4	the	the	DET
admet-400	251	5	authors	author	NOUN
admet-400	251	6	;	;	PUNCT
admet-400	251	7	licensee	licensee	PROPN
admet-400	251	8	iapc	iapc	PROPN
admet-400	251	9	,	,	PUNCT
admet-400	251	10	zagreb	zagreb	PROPN
admet-400	251	11	,	,	PUNCT
admet-400	251	12	croatia	croatia	PROPN
admet-400	251	13	.	.	PUNCT
admet-400	252	1	this	this	DET
admet-400	252	2	article	article	NOUN
admet-400	252	3	is	be	AUX
admet-400	252	4	an	an	DET
admet-400	252	5	open	open	ADJ
admet-400	252	6	-	-	PUNCT
admet-400	252	7	access	access	NOUN
admet-400	252	8	article	article	NOUN
admet-400	252	9	distributed	distribute	VERB
admet-400	252	10	under	under	ADP
admet-400	252	11	the	the	DET
admet-400	252	12	terms	term	NOUN
admet-400	252	13	and	and	CCONJ
admet-400	252	14	conditions	condition	NOUN
admet-400	252	15	of	of	ADP
admet-400	252	16	the	the	DET
admet-400	252	17	creative	creative	ADJ
admet-400	252	18	commons	common	NOUN
admet-400	252	19	attribution	attribution	NOUN
admet-400	252	20	license	license	NOUN
admet-400	252	21	(	(	PUNCT
admet-400	252	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-400	252	23	)	)	PUNCT
admet-400	252	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN