id	sid	tid	token	lemma	pos
admet-423	1	1	adme	adme	NOUN
admet-423	1	2	-	-	PUNCT
admet-423	1	3	tox	tox	NOUN
admet-423	1	4	profiling	profiling	NOUN
admet-423	1	5	of	of	ADP
admet-423	1	6	some	some	DET
admet-423	1	7	low	low	ADJ
admet-423	1	8	molecular	molecular	ADJ
admet-423	1	9	weight	weight	NOUN
admet-423	1	10	water	water	NOUN
admet-423	1	11	soluble	soluble	ADJ
admet-423	1	12	chitosan	chitosan	NOUN
admet-423	1	13	derivatives	derivative	NOUN
admet-423	1	14	doi	doi	NOUN
admet-423	1	15	:	:	PUNCT
admet-423	1	16	10.5599	10.5599	NUM
admet-423	1	17	/	/	SYM
admet-423	1	18	admet.5.3.423	admet.5.3.423	PRON
admet-423	1	19	192	192	NUM
admet-423	1	20	admet	admet	X
admet-423	1	21	&	&	CCONJ
admet-423	1	22	dmpk	dmpk	PROPN
admet-423	1	23	5(3	5(3	NUM
admet-423	1	24	)	)	PUNCT
admet-423	1	25	(	(	PUNCT
admet-423	1	26	2017	2017	NUM
admet-423	1	27	)	)	PUNCT
admet-423	1	28	192	192	NUM
admet-423	1	29	-	-	SYM
admet-423	1	30	200	200	NUM
admet-423	1	31	;	;	PUNCT
admet-423	1	32	doi	doi	NOUN
admet-423	1	33	:	:	PUNCT
admet-423	1	34	http://dx.doi.org/10.5599/admet.5.3.423	http://dx.doi.org/10.5599/admet.5.3.423	NOUN
admet-423	1	35	open	open	ADJ
admet-423	1	36	access	access	NOUN
admet-423	1	37	:	:	PUNCT
admet-423	1	38	issn	issn	PROPN
admet-423	1	39	:	:	PUNCT
admet-423	1	40	1848	1848	NUM
admet-423	1	41	-	-	SYM
admet-423	1	42	7718	7718	NUM
admet-423	1	43	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-423	1	44	original	original	ADJ
admet-423	1	45	scientific	scientific	ADJ
admet-423	1	46	paper	paper	NOUN
admet-423	1	47	adme	adme	NOUN
admet-423	1	48	-	-	PUNCT
admet-423	1	49	tox	tox	NOUN
admet-423	1	50	profiling	profiling	NOUN
admet-423	1	51	of	of	ADP
admet-423	1	52	some	some	DET
admet-423	1	53	low	low	ADJ
admet-423	1	54	molecular	molecular	ADJ
admet-423	1	55	weight	weight	NOUN
admet-423	1	56	water	water	NOUN
admet-423	1	57	soluble	soluble	ADJ
admet-423	1	58	chitosan	chitosan	NOUN
admet-423	1	59	derivatives	derivative	NOUN
admet-423	1	60	adriana	adriana	PROPN
admet-423	1	61	isvoran*1	isvoran*1	NUM
admet-423	1	62	,	,	PUNCT
admet-423	1	63	alecu	alecu	PROPN
admet-423	1	64	aurel	aurel	PROPN
admet-423	1	65	ciorsac2	ciorsac2	PROPN
admet-423	1	66	and	and	CCONJ
admet-423	1	67	vasile	vasile	PROPN
admet-423	1	68	ostafe1	ostafe1	PROPN
admet-423	1	69	1	1	NUM
admet-423	1	70	department	department	NOUN
admet-423	1	71	of	of	ADP
admet-423	1	72	biology	biology	NOUN
admet-423	1	73	-	-	PUNCT
admet-423	1	74	chemistry	chemistry	NOUN
admet-423	1	75	and	and	CCONJ
admet-423	1	76	advanced	advanced	ADJ
admet-423	1	77	environmental	environmental	ADJ
admet-423	1	78	research	research	NOUN
admet-423	1	79	laboratories	laboratory	NOUN
admet-423	1	80	,	,	PUNCT
admet-423	1	81	west	west	PROPN
admet-423	1	82	university	university	PROPN
admet-423	1	83	of	of	ADP
admet-423	1	84	timișoara	timișoara	PROPN
admet-423	1	85	,	,	PUNCT
admet-423	1	86	timișoara	timișoara	PROPN
admet-423	1	87	,	,	PUNCT
admet-423	1	88	romania	romania	PROPN
admet-423	1	89	2	2	NUM
admet-423	1	90	department	department	NOUN
admet-423	1	91	of	of	ADP
admet-423	1	92	physical	physical	ADJ
admet-423	1	93	education	education	NOUN
admet-423	1	94	and	and	CCONJ
admet-423	1	95	sport	sport	NOUN
admet-423	1	96	,	,	PUNCT
admet-423	1	97	university	university	NOUN
admet-423	1	98	politehnica	politehnica	NOUN
admet-423	1	99	timișoara	timișoara	PROPN
admet-423	1	100	,	,	PUNCT
admet-423	1	101	timișoara	timișoara	PROPN
admet-423	1	102	,	,	PUNCT
admet-423	1	103	romania	romania	PROPN
admet-423	1	104	;	;	PUNCT
admet-423	1	105	*	*	PUNCT
admet-423	1	106	corresponding	correspond	VERB
admet-423	1	107	author	author	NOUN
admet-423	1	108	:	:	PUNCT
admet-423	1	109	e	e	NOUN
admet-423	1	110	-	-	NOUN
admet-423	1	111	mail	mail	NOUN
admet-423	1	112	:	:	PUNCT
admet-423	1	113	adriana.isvoran@e-uvt.ro	adriana.isvoran@e-uvt.ro	NOUN
admet-423	1	114	;	;	PUNCT
admet-423	1	115	tel	tel	PROPN
admet-423	1	116	.	.	PROPN
admet-423	1	117	:	:	PUNCT
admet-423	2	1	+40	+40	VERB
admet-423	2	2	-	-	SYM
admet-423	2	3	256	256	NUM
admet-423	2	4	-	-	NUM
admet-423	2	5	592	592	NUM
admet-423	2	6	-	-	NUM
admet-423	2	7	634	634	NUM
admet-423	2	8	;	;	PUNCT
admet-423	2	9	fax	fax	NOUN
admet-423	2	10	:	:	PUNCT
admet-423	2	11	+40	+40	ADJ
admet-423	2	12	-	-	SYM
admet-423	2	13	256	256	NUM
admet-423	2	14	-	-	NUM
admet-423	2	15	592	592	NUM
admet-423	2	16	-	-	PUNCT
admet-423	2	17	620	620	NUM
admet-423	2	18	received	receive	VERB
admet-423	2	19	:	:	PUNCT
admet-423	2	20	august	august	PROPN
admet-423	2	21	23	23	NUM
admet-423	2	22	,	,	PUNCT
admet-423	2	23	2017	2017	NUM
admet-423	2	24	;	;	PUNCT
admet-423	2	25	revised	revise	VERB
admet-423	2	26	:	:	PUNCT
admet-423	2	27	september	september	PROPN
admet-423	2	28	26	26	NUM
admet-423	2	29	,	,	PUNCT
admet-423	2	30	2017	2017	NUM
admet-423	2	31	;	;	PUNCT
admet-423	2	32	published	publish	VERB
admet-423	2	33	:	:	PUNCT
admet-423	2	34	september	september	PROPN
admet-423	2	35	29	29	NUM
admet-423	2	36	,	,	PUNCT
admet-423	2	37	2017	2017	NUM
admet-423	2	38	abstract	abstract	NOUN
admet-423	2	39	within	within	ADP
admet-423	2	40	this	this	DET
admet-423	2	41	study	study	NOUN
admet-423	2	42	we	we	PRON
admet-423	2	43	use	use	VERB
admet-423	2	44	a	a	DET
admet-423	2	45	few	few	ADJ
admet-423	2	46	computational	computational	ADJ
admet-423	2	47	tools	tool	NOUN
admet-423	2	48	for	for	ADP
admet-423	2	49	predicting	predict	VERB
admet-423	2	50	absorption	absorption	NOUN
admet-423	2	51	,	,	PUNCT
admet-423	2	52	distribution	distribution	NOUN
admet-423	2	53	,	,	PUNCT
admet-423	2	54	metabolism	metabolism	NOUN
admet-423	2	55	,	,	PUNCT
admet-423	2	56	excretion	excretion	NOUN
admet-423	2	57	and	and	CCONJ
admet-423	2	58	toxicity	toxicity	NOUN
admet-423	2	59	(	(	PUNCT
admet-423	2	60	adme	adme	NOUN
admet-423	2	61	-	-	PUNCT
admet-423	2	62	tox	tox	NOUN
admet-423	2	63	)	)	PUNCT
admet-423	2	64	,	,	PUNCT
admet-423	2	65	pharmacokinetics	pharmacokinetic	NOUN
admet-423	2	66	profiles	profile	NOUN
admet-423	2	67	,	,	PUNCT
admet-423	2	68	toxic	toxic	ADJ
admet-423	2	69	/	/	SYM
admet-423	2	70	adverse	adverse	ADJ
admet-423	2	71	effects	effect	NOUN
admet-423	2	72	,	,	PUNCT
admet-423	2	73	carcinogenicity	carcinogenicity	NOUN
admet-423	2	74	,	,	PUNCT
admet-423	2	75	cardiotoxicity	cardiotoxicity	NOUN
admet-423	2	76	and	and	CCONJ
admet-423	2	77	endocrine	endocrine	ADJ
admet-423	2	78	disruption	disruption	NOUN
admet-423	2	79	of	of	ADP
admet-423	2	80	some	some	PRON
admet-423	2	81	of	of	ADP
admet-423	2	82	low	low	ADJ
admet-423	2	83	molecular	molecular	ADJ
admet-423	2	84	weight	weight	NOUN
admet-423	2	85	water	water	NOUN
admet-423	2	86	soluble	soluble	ADJ
admet-423	2	87	derivatives	derivative	NOUN
admet-423	2	88	of	of	ADP
admet-423	2	89	chitosan	chitosan	NOUN
admet-423	2	90	that	that	PRON
admet-423	2	91	are	be	AUX
admet-423	2	92	used	use	VERB
admet-423	2	93	in	in	ADP
admet-423	2	94	wound	wound	ADJ
admet-423	2	95	healing	healing	NOUN
admet-423	2	96	.	.	PUNCT
admet-423	3	1	investigated	investigate	VERB
admet-423	3	2	compounds	compound	NOUN
admet-423	3	3	do	do	AUX
admet-423	3	4	not	not	PART
admet-423	3	5	possess	possess	VERB
admet-423	3	6	drug	drug	NOUN
admet-423	3	7	-	-	PUNCT
admet-423	3	8	like	like	ADJ
admet-423	3	9	properties	property	NOUN
admet-423	3	10	,	,	PUNCT
admet-423	3	11	their	their	PRON
admet-423	3	12	pharmacokinetics	pharmacokinetic	NOUN
admet-423	3	13	profiles	profile	NOUN
admet-423	3	14	reveal	reveal	VERB
admet-423	3	15	poor	poor	ADJ
admet-423	3	16	gastrointestinal	gastrointestinal	ADJ
admet-423	3	17	absorption	absorption	NOUN
admet-423	3	18	and	and	CCONJ
admet-423	3	19	low	low	ADJ
admet-423	3	20	skin	skin	NOUN
admet-423	3	21	penetration	penetration	NOUN
admet-423	3	22	.	.	PUNCT
admet-423	4	1	chitosan	chitosan	NOUN
admet-423	4	2	derivatives	derivative	NOUN
admet-423	4	3	can	can	AUX
admet-423	4	4	not	not	PART
admet-423	4	5	pass	pass	VERB
admet-423	4	6	the	the	DET
admet-423	4	7	blood	blood	NOUN
admet-423	4	8	-	-	PUNCT
admet-423	4	9	brain	brain	NOUN
admet-423	4	10	barrier	barrier	NOUN
admet-423	4	11	and	and	CCONJ
admet-423	4	12	they	they	PRON
admet-423	4	13	are	be	AUX
admet-423	4	14	not	not	PART
admet-423	4	15	able	able	ADJ
admet-423	4	16	to	to	PART
admet-423	4	17	inhibit	inhibit	VERB
admet-423	4	18	the	the	DET
admet-423	4	19	enzymes	enzyme	NOUN
admet-423	4	20	of	of	ADP
admet-423	4	21	the	the	DET
admet-423	4	22	cytochrome	cytochrome	NOUN
admet-423	4	23	p450	p450	PROPN
admet-423	4	24	that	that	PRON
admet-423	4	25	are	be	AUX
admet-423	4	26	involved	involve	VERB
admet-423	4	27	in	in	ADP
admet-423	4	28	the	the	DET
admet-423	4	29	metabolism	metabolism	NOUN
admet-423	4	30	of	of	ADP
admet-423	4	31	xenobiotics	xenobiotics	PROPN
admet-423	4	32	.	.	PUNCT
admet-423	5	1	they	they	PRON
admet-423	5	2	do	do	AUX
admet-423	5	3	not	not	PART
admet-423	5	4	reflect	reflect	VERB
admet-423	5	5	carcinogenicity	carcinogenicity	NOUN
admet-423	5	6	and	and	CCONJ
admet-423	5	7	cardiotoxicity	cardiotoxicity	NOUN
admet-423	5	8	and	and	CCONJ
admet-423	5	9	reveal	reveal	VERB
admet-423	5	10	only	only	ADV
admet-423	5	11	a	a	DET
admet-423	5	12	low	low	ADJ
admet-423	5	13	probability	probability	NOUN
admet-423	5	14	to	to	PART
admet-423	5	15	be	be	AUX
admet-423	5	16	endocrine	endocrine	ADJ
admet-423	5	17	disruptors	disruptor	NOUN
admet-423	5	18	.	.	PUNCT
admet-423	6	1	the	the	DET
admet-423	6	2	main	main	ADJ
admet-423	6	3	side	side	NOUN
admet-423	6	4	effects	effect	NOUN
admet-423	6	5	in	in	ADP
admet-423	6	6	humans	human	NOUN
admet-423	6	7	of	of	ADP
admet-423	6	8	the	the	DET
admet-423	6	9	investigated	investigate	VERB
admet-423	6	10	compounds	compound	NOUN
admet-423	6	11	are	be	AUX
admet-423	6	12	:	:	PUNCT
admet-423	6	13	weight	weight	NOUN
admet-423	6	14	loss	loss	NOUN
admet-423	6	15	,	,	PUNCT
admet-423	6	16	acidosis	acidosis	NOUN
admet-423	6	17	,	,	PUNCT
admet-423	6	18	gastrointestinal	gastrointestinal	ADJ
admet-423	6	19	toxicity	toxicity	NOUN
admet-423	6	20	,	,	PUNCT
admet-423	6	21	respiratory	respiratory	ADJ
admet-423	6	22	failure	failure	NOUN
admet-423	6	23	.	.	PUNCT
admet-423	7	1	this	this	DET
admet-423	7	2	information	information	NOUN
admet-423	7	3	is	be	AUX
admet-423	7	4	especially	especially	ADV
admet-423	7	5	important	important	ADJ
admet-423	7	6	for	for	ADP
admet-423	7	7	professional	professional	ADJ
admet-423	7	8	exposure	exposure	NOUN
admet-423	7	9	and	and	CCONJ
admet-423	7	10	accidental	accidental	ADJ
admet-423	7	11	contamination	contamination	NOUN
admet-423	7	12	with	with	ADP
admet-423	7	13	these	these	DET
admet-423	7	14	compounds	compound	NOUN
admet-423	7	15	.	.	PUNCT
admet-423	8	1	keywords	keyword	VERB
admet-423	8	2	pharmacokinetics	pharmacokinetic	NOUN
admet-423	8	3	;	;	PUNCT
admet-423	8	4	toxic	toxic	ADJ
admet-423	8	5	/	/	SYM
admet-423	8	6	adverse	adverse	ADJ
admet-423	8	7	effects	effect	NOUN
admet-423	8	8	;	;	PUNCT
admet-423	8	9	carcinogenicity	carcinogenicity	NOUN
admet-423	8	10	;	;	PUNCT
admet-423	8	11	cardiotoxicity	cardiotoxicity	NOUN
admet-423	8	12	;	;	PUNCT
admet-423	8	13	endocrine	endocrine	ADJ
admet-423	8	14	disruption	disruption	NOUN
admet-423	8	15	.	.	PUNCT
admet-423	9	1	introduction	introduction	NOUN
admet-423	9	2	chitosan	chitosan	NOUN
admet-423	9	3	is	be	AUX
admet-423	9	4	a	a	DET
admet-423	9	5	cationic	cationic	ADJ
admet-423	9	6	polysaccharide	polysaccharide	NOUN
admet-423	9	7	obtained	obtain	VERB
admet-423	9	8	from	from	ADP
admet-423	9	9	chitin	chitin	NOUN
admet-423	9	10	and	and	CCONJ
admet-423	9	11	composed	compose	VERB
admet-423	9	12	by	by	ADP
admet-423	9	13	glucosamine	glucosamine	NOUN
admet-423	9	14	and	and	CCONJ
admet-423	9	15	n	n	CCONJ
admet-423	9	16	-	-	PUNCT
admet-423	9	17	acetyl	acetyl	NOUN
admet-423	9	18	glucosamine	glucosamine	NOUN
admet-423	9	19	units	unit	NOUN
admet-423	9	20	,	,	PUNCT
admet-423	9	21	via	via	ADP
admet-423	9	22	β-(1,4	β-(1,4	ADV
admet-423	9	23	)	)	PUNCT
admet-423	9	24	linkages	linkage	NOUN
admet-423	9	25	.	.	PUNCT
admet-423	10	1	it	it	PRON
admet-423	10	2	differs	differ	VERB
admet-423	10	3	from	from	ADP
admet-423	10	4	chitin	chitin	NOUN
admet-423	10	5	by	by	ADP
admet-423	10	6	having	have	VERB
admet-423	10	7	free	free	ADJ
admet-423	10	8	amino	amino	NOUN
admet-423	10	9	groups	group	NOUN
admet-423	10	10	.	.	PUNCT
admet-423	11	1	chitosan	chitosan	NOUN
admet-423	11	2	is	be	AUX
admet-423	11	3	considered	consider	VERB
admet-423	11	4	to	to	PART
admet-423	11	5	have	have	VERB
admet-423	11	6	favourable	favourable	ADJ
admet-423	11	7	biological	biological	ADJ
admet-423	11	8	properties	property	NOUN
admet-423	11	9	revealing	reveal	VERB
admet-423	11	10	nontoxicity	nontoxicity	NOUN
admet-423	11	11	,	,	PUNCT
admet-423	11	12	mucoadhesivity	mucoadhesivity	NOUN
admet-423	11	13	,	,	PUNCT
admet-423	11	14	biocompatibility	biocompatibility	NOUN
admet-423	11	15	and	and	CCONJ
admet-423	11	16	biodegradability	biodegradability	NOUN
admet-423	11	17	,	,	PUNCT
admet-423	11	18	but	but	CCONJ
admet-423	11	19	it	it	PRON
admet-423	11	20	is	be	AUX
admet-423	11	21	only	only	ADV
admet-423	11	22	soluble	soluble	ADJ
admet-423	11	23	in	in	ADP
admet-423	11	24	acidic	acidic	ADJ
admet-423	11	25	environments	environment	NOUN
admet-423	12	1	[	[	X
admet-423	12	2	1	1	NUM
admet-423	12	3	-	-	SYM
admet-423	12	4	3	3	NUM
admet-423	12	5	]	]	PUNCT
admet-423	12	6	.	.	PUNCT
admet-423	13	1	water	water	NOUN
admet-423	13	2	soluble	soluble	ADJ
admet-423	13	3	derivatives	derivative	NOUN
admet-423	13	4	of	of	ADP
admet-423	13	5	chitosan	chitosan	NOUN
admet-423	13	6	(	(	PUNCT
admet-423	13	7	wsdc	wsdc	ADJ
admet-423	13	8	)	)	PUNCT
admet-423	13	9	are	be	AUX
admet-423	13	10	considered	consider	VERB
admet-423	13	11	to	to	PART
admet-423	13	12	have	have	VERB
admet-423	13	13	the	the	DET
admet-423	13	14	similar	similar	ADJ
admet-423	13	15	favourable	favourable	ADJ
admet-423	13	16	properties	property	NOUN
admet-423	13	17	with	with	ADP
admet-423	13	18	chitosan	chitosan	NOUN
admet-423	13	19	,	,	PUNCT
admet-423	13	20	but	but	CCONJ
admet-423	13	21	they	they	PRON
admet-423	13	22	can	can	AUX
admet-423	13	23	be	be	AUX
admet-423	13	24	dissolved	dissolve	VERB
admet-423	13	25	in	in	ADP
admet-423	13	26	aqueous	aqueous	ADJ
admet-423	13	27	media	medium	NOUN
admet-423	13	28	.	.	PUNCT
admet-423	14	1	wsdc	wsdc	PROPN
admet-423	14	2	are	be	AUX
admet-423	14	3	interesting	interesting	ADJ
admet-423	14	4	biomaterials	biomaterial	NOUN
admet-423	14	5	with	with	ADP
admet-423	14	6	numerous	numerous	ADJ
admet-423	14	7	applications	application	NOUN
admet-423	14	8	in	in	ADP
admet-423	14	9	bioengineering	bioengineering	NOUN
admet-423	14	10	and	and	CCONJ
admet-423	14	11	biopharmaceutical	biopharmaceutical	NOUN
admet-423	14	12	fields	field	NOUN
admet-423	14	13	[	[	X
admet-423	14	14	4	4	NUM
admet-423	14	15	]	]	PUNCT
admet-423	14	16	,	,	PUNCT
admet-423	14	17	their	their	PRON
admet-423	14	18	preparation	preparation	NOUN
admet-423	14	19	being	be	AUX
admet-423	14	20	one	one	NUM
admet-423	14	21	of	of	ADP
admet-423	14	22	the	the	DET
admet-423	14	23	most	most	ADV
admet-423	14	24	commonly	commonly	ADV
admet-423	14	25	used	use	VERB
admet-423	14	26	chemical	chemical	NOUN
admet-423	14	27	modifications	modification	NOUN
admet-423	14	28	of	of	ADP
admet-423	14	29	chitosan	chitosan	NOUN
admet-423	14	30	for	for	ADP
admet-423	14	31	biomedical	biomedical	ADJ
admet-423	14	32	purposes	purpose	NOUN
admet-423	14	33	.	.	PUNCT
admet-423	15	1	as	as	ADP
admet-423	15	2	pharmaceutical	pharmaceutical	ADJ
admet-423	15	3	applications	application	NOUN
admet-423	15	4	,	,	PUNCT
admet-423	15	5	literature	literature	NOUN
admet-423	15	6	data	datum	NOUN
admet-423	15	7	reveal	reveal	VERB
admet-423	15	8	that	that	SCONJ
admet-423	15	9	chitosan	chitosan	NOUN
admet-423	15	10	and	and	CCONJ
admet-423	15	11	wsdc	wsdc	NOUN
admet-423	15	12	are	be	AUX
admet-423	15	13	used	use	VERB
admet-423	15	14	as	as	ADP
admet-423	15	15	carriers	carrier	NOUN
admet-423	15	16	for	for	ADP
admet-423	15	17	radioactive	radioactive	ADJ
admet-423	15	18	elements	element	NOUN
admet-423	15	19	,	,	PUNCT
admet-423	15	20	carriers	carrier	NOUN
admet-423	15	21	for	for	ADP
admet-423	15	22	drug	drug	NOUN
admet-423	15	23	delivery	delivery	NOUN
admet-423	15	24	and	and	CCONJ
admet-423	15	25	release	release	NOUN
admet-423	15	26	systems	system	NOUN
admet-423	15	27	and	and	CCONJ
admet-423	15	28	they	they	PRON
admet-423	15	29	have	have	VERB
admet-423	15	30	antimicrobial	antimicrobial	ADJ
admet-423	15	31	properties	property	NOUN
admet-423	15	32	[	[	X
admet-423	15	33	2	2	NUM
admet-423	15	34	]	]	PUNCT
admet-423	15	35	.	.	PUNCT
admet-423	16	1	some	some	DET
admet-423	16	2	wsdc	wsdc	NOUN
admet-423	16	3	are	be	AUX
admet-423	16	4	used	use	VERB
admet-423	16	5	to	to	PART
admet-423	16	6	accelerate	accelerate	VERB
admet-423	16	7	wound	wound	ADJ
admet-423	16	8	healing	healing	NOUN
admet-423	16	9	[	[	X
admet-423	16	10	5	5	NUM
admet-423	16	11	]	]	PUNCT
admet-423	16	12	.	.	PUNCT
admet-423	17	1	despite	despite	SCONJ
admet-423	17	2	literature	literature	NOUN
admet-423	17	3	data	datum	NOUN
admet-423	17	4	revealing	reveal	VERB
admet-423	17	5	their	their	PRON
admet-423	17	6	use	use	NOUN
admet-423	17	7	in	in	ADP
admet-423	17	8	biomedical	biomedical	ADJ
admet-423	17	9	applications	application	NOUN
admet-423	17	10	,	,	PUNCT
admet-423	17	11	chitosan	chitosan	NOUN
admet-423	17	12	and	and	CCONJ
admet-423	17	13	its	its	PRON
admet-423	17	14	water	water	NOUN
admet-423	17	15	soluble	soluble	ADJ
admet-423	17	16	derivatives	derivative	NOUN
admet-423	17	17	are	be	AUX
admet-423	17	18	not	not	PART
admet-423	17	19	approved	approve	VERB
admet-423	17	20	by	by	ADP
admet-423	17	21	the	the	DET
admet-423	17	22	us	us	PROPN
admet-423	17	23	food	food	NOUN
admet-423	17	24	and	and	CCONJ
admet-423	17	25	drug	drug	PROPN
admet-423	17	26	administration	administration	PROPN
admet-423	17	27	(	(	PUNCT
admet-423	17	28	fda	fda	PROPN
admet-423	17	29	)	)	PUNCT
admet-423	17	30	for	for	ADP
admet-423	17	31	drug	drug	NOUN
admet-423	17	32	delivery	delivery	NOUN
admet-423	17	33	,	,	PUNCT
admet-423	17	34	they	they	PRON
admet-423	17	35	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	VERB
admet-423	17	36	mailto:name@address.domain	mailto:name@address.domain	PROPN
admet-423	17	37	admet	admet	PROPN
admet-423	17	38	&	&	CCONJ
admet-423	17	39	dmpk	dmpk	PROPN
admet-423	17	40	5(3	5(3	NUM
admet-423	17	41	)	)	PUNCT
admet-423	17	42	(	(	PUNCT
admet-423	17	43	2017	2017	NUM
admet-423	17	44	)	)	PUNCT
admet-423	17	45	192	192	NUM
admet-423	17	46	-	-	SYM
admet-423	17	47	200	200	NUM
admet-423	17	48	admet	admet	NOUN
admet-423	17	49	of	of	ADP
admet-423	17	50	chitosan	chitosan	NOUN
admet-423	17	51	derivatives	derivative	NOUN
admet-423	17	52	doi	doi	NOUN
admet-423	17	53	:	:	PUNCT
admet-423	17	54	10.5599	10.5599	NUM
admet-423	17	55	/	/	SYM
admet-423	17	56	admet.5.3.423	admet.5.3.423	PRON
admet-423	17	57	193	193	NUM
admet-423	17	58	are	be	AUX
admet-423	17	59	only	only	ADV
admet-423	17	60	approved	approve	VERB
admet-423	17	61	to	to	PART
admet-423	17	62	be	be	AUX
admet-423	17	63	used	use	VERB
admet-423	17	64	for	for	ADP
admet-423	17	65	wound	wound	ADJ
admet-423	17	66	healing	healing	NOUN
admet-423	17	67	[	[	X
admet-423	17	68	6	6	NUM
admet-423	17	69	]	]	PUNCT
admet-423	17	70	and	and	CCONJ
admet-423	17	71	as	as	ADP
admet-423	17	72	dietary	dietary	ADJ
admet-423	17	73	additives	additive	NOUN
admet-423	17	74	in	in	ADP
admet-423	17	75	japan	japan	PROPN
admet-423	17	76	,	,	PUNCT
admet-423	17	77	italy	italy	PROPN
admet-423	17	78	and	and	CCONJ
admet-423	17	79	finland	finland	PROPN
admet-423	18	1	[	[	X
admet-423	18	2	7	7	NUM
admet-423	18	3	]	]	PUNCT
admet-423	18	4	.	.	PUNCT
admet-423	19	1	there	there	PRON
admet-423	19	2	are	be	VERB
admet-423	19	3	limited	limited	ADJ
admet-423	19	4	data	datum	NOUN
admet-423	19	5	in	in	ADP
admet-423	19	6	specific	specific	ADJ
admet-423	19	7	literature	literature	NOUN
admet-423	19	8	concerning	concern	VERB
admet-423	19	9	the	the	DET
admet-423	19	10	effects	effect	NOUN
admet-423	19	11	of	of	ADP
admet-423	19	12	chitosan	chitosan	NOUN
admet-423	19	13	and	and	CCONJ
admet-423	19	14	chitosan	chitosan	NOUN
admet-423	19	15	derivatives	derivative	NOUN
admet-423	19	16	on	on	ADP
admet-423	19	17	humans	human	NOUN
admet-423	19	18	,	,	PUNCT
admet-423	19	19	most	most	ADJ
admet-423	19	20	in	in	ADP
admet-423	19	21	vivo	vivo	ADJ
admet-423	19	22	data	datum	NOUN
admet-423	19	23	being	be	AUX
admet-423	19	24	obtained	obtain	VERB
admet-423	19	25	from	from	ADP
admet-423	19	26	studies	study	NOUN
admet-423	19	27	performed	perform	VERB
admet-423	19	28	on	on	ADP
admet-423	19	29	animals	animal	NOUN
admet-423	19	30	,	,	PUNCT
admet-423	19	31	usually	usually	ADV
admet-423	19	32	rodents	rodent	VERB
admet-423	19	33	[	[	X
admet-423	19	34	3	3	NUM
admet-423	19	35	]	]	PUNCT
admet-423	19	36	.	.	PUNCT
admet-423	20	1	the	the	DET
admet-423	20	2	aim	aim	NOUN
admet-423	20	3	of	of	ADP
admet-423	20	4	this	this	DET
admet-423	20	5	study	study	NOUN
admet-423	20	6	is	be	AUX
admet-423	20	7	to	to	PART
admet-423	20	8	predict	predict	VERB
admet-423	20	9	the	the	DET
admet-423	20	10	adme	adme	NOUN
admet-423	20	11	-	-	PUNCT
admet-423	20	12	tox	tox	NOUN
admet-423	20	13	profiles	profile	NOUN
admet-423	20	14	,	,	PUNCT
admet-423	20	15	pharmacokinetics	pharmacokinetic	NOUN
admet-423	20	16	and	and	CCONJ
admet-423	20	17	toxic	toxic	ADJ
admet-423	20	18	/	/	SYM
admet-423	20	19	adverse	adverse	ADJ
admet-423	20	20	effects	effect	NOUN
admet-423	20	21	of	of	ADP
admet-423	20	22	some	some	DET
admet-423	20	23	low	low	ADJ
admet-423	20	24	molecular	molecular	ADJ
admet-423	20	25	weight	weight	NOUN
admet-423	20	26	wsdc	wsdc	NOUN
admet-423	20	27	that	that	PRON
admet-423	20	28	can	can	AUX
admet-423	20	29	be	be	AUX
admet-423	20	30	used	use	VERB
admet-423	20	31	for	for	ADP
admet-423	20	32	wound	wound	NOUN
admet-423	20	33	healing	healing	NOUN
admet-423	20	34	and	and	CCONJ
admet-423	20	35	to	to	PART
admet-423	20	36	compare	compare	VERB
admet-423	20	37	them	they	PRON
admet-423	20	38	with	with	ADP
admet-423	20	39	those	those	PRON
admet-423	20	40	of	of	ADP
admet-423	20	41	deacetylated	deacetylate	VERB
admet-423	20	42	chitosan	chitosan	NOUN
admet-423	20	43	and	and	CCONJ
admet-423	20	44	partially	partially	ADV
admet-423	20	45	deacetylated	deacetylate	VERB
admet-423	20	46	chitosan	chitosan	NOUN
admet-423	20	47	.	.	PUNCT
admet-423	21	1	methodology	methodology	NOUN
admet-423	21	2	in	in	ADP
admet-423	21	3	vitro	vitro	X
admet-423	21	4	studies	study	NOUN
admet-423	21	5	revealed	reveal	VERB
admet-423	21	6	that	that	SCONJ
admet-423	21	7	chitosan	chitosan	NOUN
admet-423	21	8	and	and	CCONJ
admet-423	21	9	some	some	PRON
admet-423	21	10	of	of	ADP
admet-423	21	11	its	its	PRON
admet-423	21	12	water	water	NOUN
admet-423	21	13	soluble	soluble	ADJ
admet-423	21	14	derivatives	derivative	NOUN
admet-423	21	15	have	have	VERB
admet-423	21	16	antifungal	antifungal	ADJ
admet-423	21	17	activity	activity	NOUN
admet-423	21	18	and	and	CCONJ
admet-423	21	19	may	may	AUX
admet-423	21	20	be	be	AUX
admet-423	21	21	used	use	VERB
admet-423	21	22	for	for	ADP
admet-423	21	23	wound	wound	ADJ
admet-423	21	24	healing	healing	NOUN
admet-423	21	25	purposes	purpose	NOUN
admet-423	21	26	[	[	X
admet-423	21	27	5	5	NUM
admet-423	21	28	,	,	PUNCT
admet-423	21	29	8	8	NUM
admet-423	21	30	-	-	SYM
admet-423	21	31	11	11	NUM
admet-423	21	32	]	]	PUNCT
admet-423	21	33	.	.	PUNCT
admet-423	22	1	according	accord	VERB
admet-423	22	2	to	to	ADP
admet-423	22	3	these	these	DET
admet-423	22	4	findings	finding	NOUN
admet-423	22	5	,	,	PUNCT
admet-423	22	6	we	we	PRON
admet-423	22	7	considered	consider	VERB
admet-423	22	8	in	in	ADP
admet-423	22	9	this	this	DET
admet-423	22	10	study	study	NOUN
admet-423	22	11	14	14	NUM
admet-423	22	12	low	low	ADJ
admet-423	22	13	molecular	molecular	ADJ
admet-423	22	14	weight	weight	NOUN
admet-423	22	15	wsdc	wsdc	NOUN
admet-423	22	16	known	know	VERB
admet-423	22	17	to	to	PART
admet-423	22	18	be	be	AUX
admet-423	22	19	useful	useful	ADJ
admet-423	22	20	for	for	ADP
admet-423	22	21	wound	wound	ADJ
admet-423	22	22	healing	healing	NOUN
admet-423	22	23	.	.	PUNCT
admet-423	23	1	in	in	ADP
admet-423	23	2	addition	addition	NOUN
admet-423	23	3	,	,	PUNCT
admet-423	23	4	for	for	ADP
admet-423	23	5	comparison	comparison	NOUN
admet-423	23	6	purposes	purpose	NOUN
admet-423	23	7	,	,	PUNCT
admet-423	23	8	we	we	PRON
admet-423	23	9	consider	consider	VERB
admet-423	23	10	deacetylated	deacetylate	VERB
admet-423	23	11	chitosan	chitosan	NOUN
admet-423	23	12	and	and	CCONJ
admet-423	23	13	partially	partially	ADV
admet-423	23	14	deacetylated	deacetylate	VERB
admet-423	23	15	chitosan	chitosan	NOUN
admet-423	23	16	,	,	PUNCT
admet-423	23	17	all	all	DET
admet-423	23	18	investigated	investigate	VERB
admet-423	23	19	compounds	compound	NOUN
admet-423	23	20	being	be	AUX
admet-423	23	21	presented	present	VERB
admet-423	23	22	in	in	ADP
admet-423	23	23	table	table	NOUN
admet-423	23	24	1	1	NUM
admet-423	23	25	.	.	PUNCT
admet-423	24	1	their	their	PRON
admet-423	24	2	simplified	simplified	ADJ
admet-423	24	3	molecular	molecular	ADJ
admet-423	24	4	-	-	PUNCT
admet-423	24	5	input	input	NOUN
admet-423	24	6	line	line	NOUN
admet-423	24	7	-	-	PUNCT
admet-423	24	8	entry	entry	NOUN
admet-423	24	9	system	system	NOUN
admet-423	24	10	(	(	PUNCT
admet-423	24	11	smiles	smile	NOUN
admet-423	24	12	)	)	PUNCT
admet-423	24	13	structures	structure	NOUN
admet-423	24	14	were	be	AUX
admet-423	24	15	obtained	obtain	VERB
admet-423	24	16	using	use	VERB
admet-423	24	17	acd	acd	NOUN
admet-423	24	18	/	/	SYM
admet-423	24	19	chemsketch	chemsketch	NOUN
admet-423	24	20	[	[	X
admet-423	24	21	12	12	NUM
admet-423	24	22	]	]	PUNCT
admet-423	24	23	and	and	CCONJ
admet-423	24	24	are	be	AUX
admet-423	24	25	used	use	VERB
admet-423	24	26	for	for	ADP
admet-423	24	27	further	further	ADJ
admet-423	24	28	predictions	prediction	NOUN
admet-423	24	29	.	.	PUNCT
admet-423	25	1	when	when	SCONJ
admet-423	25	2	the	the	DET
admet-423	25	3	structural	structural	ADJ
admet-423	25	4	data	data	NOUN
admet-423	25	5	files	file	NOUN
admet-423	25	6	(	(	PUNCT
admet-423	25	7	sdf	sdf	NOUN
admet-423	25	8	)	)	PUNCT
admet-423	25	9	of	of	ADP
admet-423	25	10	compounds	compound	NOUN
admet-423	25	11	are	be	AUX
admet-423	25	12	needed	need	VERB
admet-423	25	13	for	for	ADP
admet-423	25	14	predictions	prediction	NOUN
admet-423	25	15	,	,	PUNCT
admet-423	25	16	the	the	DET
admet-423	25	17	online	online	ADJ
admet-423	25	18	translation	translation	NOUN
admet-423	25	19	of	of	ADP
admet-423	25	20	smiles	smile	NOUN
admet-423	25	21	to	to	ADP
admet-423	25	22	sdf	sdf	NOUN
admet-423	25	23	files	file	NOUN
admet-423	25	24	is	be	AUX
admet-423	25	25	used	use	VERB
admet-423	25	26	[	[	PUNCT
admet-423	25	27	13	13	NUM
admet-423	25	28	]	]	PUNCT
admet-423	25	29	.	.	PUNCT
admet-423	26	1	table	table	NOUN
admet-423	26	2	1	1	NUM
admet-423	26	3	.	.	PUNCT
admet-423	27	1	molecules	molecule	NOUN
admet-423	27	2	of	of	ADP
admet-423	27	3	wscd	wscd	NOUN
admet-423	27	4	considered	consider	VERB
admet-423	27	5	in	in	ADP
admet-423	27	6	this	this	DET
admet-423	27	7	study	study	NOUN
admet-423	27	8	compound	compound	VERB
admet-423	27	9	common	common	ADJ
admet-423	27	10	name	name	NOUN
admet-423	27	11	smiles	smile	VERB
admet-423	27	12	deacetylated	deacetylate	VERB
admet-423	27	13	chitosan	chitosan	NOUN
admet-423	27	14	(	(	PUNCT
admet-423	27	15	2	2	NUM
admet-423	27	16	units	unit	NOUN
admet-423	27	17	)	)	PUNCT
admet-423	27	18	o[c@h]2c(o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1n)[c@h](co)oc	o[c@h]2c(o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1n)[c@h](co)oc	PUNCT
admet-423	28	1	(	(	PUNCT
admet-423	28	2	o)c2n	o)c2n	PROPN
admet-423	28	3	partially	partially	ADV
admet-423	28	4	deacetylated	deacetylate	VERB
admet-423	28	5	chitosan	chitosan	NOUN
admet-423	28	6	(	(	PUNCT
admet-423	28	7	2	2	NUM
admet-423	28	8	units	unit	NOUN
admet-423	28	9	)	)	PUNCT
admet-423	28	10	cc(=o)nc2c(o)[c@h](o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1n)c(c	cc(=o)nc2c(o)[c@h](o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1n)c(c	NOUN
admet-423	28	11	o)o[c@h]2o	o)o[c@h]2o	PROPN
admet-423	28	12	n	n	CCONJ
admet-423	28	13	-	-	PUNCT
admet-423	28	14	carboxymethyl	carboxymethyl	NOUN
admet-423	28	15	chitosan	chitosan	NOUN
admet-423	28	16	o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1ncc(=o)o	o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1ncc(=o)o	PROPN
admet-423	29	1	o	o	NOUN
admet-423	29	2	-	-	NOUN
admet-423	29	3	carboxymethyl	carboxymethyl	NOUN
admet-423	29	4	chitosan	chitosan	NOUN
admet-423	29	5	oc1[c@h](o)c(cocc(=o)o)o[c@@h](o)c1n	oc1[c@h](o)c(cocc(=o)o)o[c@@h](o)c1n	PROPN
admet-423	29	6	n	n	CCONJ
admet-423	29	7	,	,	PUNCT
admet-423	29	8	n	n	CCONJ
admet-423	29	9	-	-	PUNCT
admet-423	29	10	carboxymethyl	carboxymethyl	NOUN
admet-423	29	11	chitosan	chitosan	NOUN
admet-423	29	12	o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1n(cc(=o)o)cc(=o)o	o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1n(cc(=o)o)cc(=o)o	PROPN
admet-423	29	13	n	n	NOUN
admet-423	29	14	,	,	PUNCT
admet-423	29	15	o	o	NOUN
admet-423	29	16	-	-	NOUN
admet-423	29	17	carboxymethyl	carboxymethyl	NOUN
admet-423	29	18	chitosan	chitosan	NOUN
admet-423	29	19	o[c@@h]1oc(cocc(=o)o)[c@@h](o)c(o)c1ncc(=o)o	o[c@@h]1oc(cocc(=o)o)[c@@h](o)c(o)c1ncc(=o)o	PROPN
admet-423	29	20	n	n	CCONJ
admet-423	29	21	,	,	PUNCT
admet-423	29	22	n	n	CCONJ
admet-423	29	23	,	,	PUNCT
admet-423	29	24	o	o	NOUN
admet-423	29	25	-	-	NOUN
admet-423	29	26	carboxymethyl	carboxymethyl	NOUN
admet-423	29	27	chitosan	chitosan	NOUN
admet-423	29	28	o[c@@h]1oc(cocc(=o)o)[c@@h](o)[c@h](o)c1n(cc(=o)o)cc(=o)o	o[c@@h]1oc(cocc(=o)o)[c@@h](o)[c@h](o)c1n(cc(=o)o)cc(=o)o	PROPN
admet-423	29	29	n	n	CCONJ
admet-423	29	30	,	,	PUNCT
admet-423	29	31	n	n	CCONJ
admet-423	29	32	,	,	PUNCT
admet-423	29	33	n	n	PRON
admet-423	29	34	-trimethyl	-trimethyl	NOUN
admet-423	29	35	-	-	PUNCT
admet-423	29	36	chitosan	chitosan	PROPN
admet-423	29	37	c[n+](c)(c)c2[c@@h](o)[c@h](o)c(co)o[c@h]2o[c@@h]1c(co)o[c	c[n+](c)(c)c2[c@@h](o)[c@h](o)c(co)o[c@h]2o[c@@h]1c(co)o[c	VERB
admet-423	29	38	@@h](o)c(n)c1o	@@h](o)c(n)c1o	PROPN
admet-423	29	39	chitosan	chitosan	NOUN
admet-423	29	40	-	-	PUNCT
admet-423	29	41	lactate	lactate	NOUN
admet-423	29	42	o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1nc(=o)c(c)o	o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1nc(=o)c(c)o	ADJ
admet-423	29	43	hydroxyethyl	hydroxyethyl	NOUN
admet-423	29	44	chitosan	chitosan	PROPN
admet-423	29	45	cc(=o)nc2c(o)[c@h](o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1ncco	cc(=o)nc2c(o)[c@h](o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1ncco	PROPN
admet-423	29	46	)	)	PUNCT
admet-423	29	47	c(cocco)o[c@h]2o	c(cocco)o[c@h]2o	NOUN
admet-423	29	48	hydroxypropyl	hydroxypropyl	VERB
admet-423	29	49	chitosan	chitosan	PROPN
admet-423	29	50	cc(=o)nc2c(o)[c@h](o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1ncc(c	cc(=o)nc2c(o)[c@h](o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1ncc(c	PROPN
admet-423	29	51	)	)	PUNCT
admet-423	29	52	o)c(cocc(c)o)o[c@h]2o	o)c(cocc(c)o)o[c@h]2o	NOUN
admet-423	29	53	dihydroxypropyl	dihydroxypropyl	NOUN
admet-423	29	54	chitosan	chitosan	PROPN
admet-423	29	55	cc(o)cn(cc(c)o)c2[c@@h](o)[c@h](o)c(co)o[c@h]2o[c@@h]1c(c	cc(o)cn(cc(c)o)c2[c@@h](o)[c@h](o)c(co)o[c@h]2o[c@@h]1c(c	PROPN
admet-423	29	56	o)o[c@@h](o)c(nc(c)=o)c1o	o)o[c@@h](o)c(nc(c)=o)c1o	PRON
admet-423	29	57	n-(2	n-(2	PROPN
admet-423	29	58	-	-	PUNCT
admet-423	29	59	hydroxy)propyl-3trimethylammonium	hydroxy)propyl-3trimethylammonium	NOUN
admet-423	29	60	chitosan	chitosan	NOUN
admet-423	29	61	c[n+](c)(c)cc(o)cnc2[c@@h](o)[c@h](o)c(co)o[c@h]2o[c@@h]1c	c[n+](c)(c)cc(o)cnc2[c@@h](o)[c@h](o)c(co)o[c@h]2o[c@@h]1c	PROPN
admet-423	29	62	(	(	PUNCT
admet-423	29	63	co)o[c@@h](o)c(nc(c)=o)c1o	co)o[c@@h](o)c(nc(c)=o)c1o	PROPN
admet-423	29	64	o-(2	o-(2	NOUN
admet-423	29	65	-	-	PUNCT
admet-423	29	66	hydroxy)propyl-3trimethylammonium	hydroxy)propyl-3trimethylammonium	NOUN
admet-423	29	67	chitosan	chitosan	ADJ
admet-423	29	68	c[n+](c)(c)cc(o)cocc2o[c@@h](o)c(nc(c)=o)c(o)[c@@h]2o[c@@h	c[n+](c)(c)cc(o)cocc2o[c@@h](o)c(nc(c)=o)c(o)[c@@h]2o[c@@h	NOUN
admet-423	29	69	]	]	X
admet-423	29	70	1oc(co)[c@@h](o)[c@h](o)c1n	1oc(co)[c@@h](o)[c@h](o)c1n	PROPN
admet-423	29	71	n-(4	n-(4	ADV
admet-423	29	72	-	-	PUNCT
admet-423	29	73	carboxybutyroyl	carboxybutyroyl	NOUN
admet-423	29	74	)	)	PUNCT
admet-423	29	75	chitosan	chitosan	PROPN
admet-423	29	76	cc(=o)nc2c(o)[c@h](o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1nc(=o	cc(=o)nc2c(o)[c@h](o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1nc(=o	NOUN
admet-423	29	77	)	)	PUNCT
admet-423	29	78	ccc)c(co)o[c@h]2o	ccc)c(co)o[c@h]2o	VERB
admet-423	29	79	n	n	CCONJ
admet-423	29	80	-	-	PUNCT
admet-423	29	81	trimethyl	trimethyl	NOUN
admet-423	29	82	chitosan	chitosan	NOUN
admet-423	29	83	cc(=o)nc2c(o)[c@h](o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1[n+](c	cc(=o)nc2c(o)[c@h](o[c@@h]1oc(co)[c@@h](o)[c@h](o)c1[n+](c	PROPN
admet-423	29	84	)	)	PUNCT
admet-423	30	1	(	(	PUNCT
admet-423	30	2	c)c)c(co)o[c@h]2o	c)c)c(co)o[c@h]2o	NOUN
admet-423	30	3	for	for	ADP
admet-423	30	4	the	the	DET
admet-423	30	5	compounds	compound	NOUN
admet-423	30	6	considered	consider	VERB
admet-423	30	7	in	in	ADP
admet-423	30	8	this	this	DET
admet-423	30	9	study	study	NOUN
admet-423	30	10	we	we	PRON
admet-423	30	11	use	use	VERB
admet-423	30	12	the	the	DET
admet-423	30	13	following	follow	VERB
admet-423	30	14	computational	computational	ADJ
admet-423	30	15	tools	tool	NOUN
admet-423	30	16	:	:	PUNCT
admet-423	30	17	(	(	PUNCT
admet-423	30	18	i	i	NOUN
admet-423	30	19	)	)	PUNCT
admet-423	30	20	swissadme	swissadme	NOUN
admet-423	30	21	[	[	X
admet-423	30	22	14	14	NUM
admet-423	30	23	]	]	PUNCT
admet-423	30	24	and	and	CCONJ
admet-423	30	25	fafdrugs	fafdrug	NOUN
admet-423	30	26	[	[	X
admet-423	30	27	15	15	NUM
admet-423	30	28	,	,	PUNCT
admet-423	30	29	16	16	NUM
admet-423	30	30	]	]	PUNCT
admet-423	30	31	to	to	PART
admet-423	30	32	assess	assess	VERB
admet-423	30	33	their	their	PRON
admet-423	30	34	pharmacokinetics	pharmacokinetic	NOUN
admet-423	30	35	and	and	CCONJ
admet-423	30	36	to	to	PART
admet-423	30	37	predict	predict	VERB
admet-423	30	38	their	their	PRON
admet-423	30	39	adme	adme	NOUN
admet-423	30	40	-	-	PUNCT
admet-423	30	41	tox	tox	NOUN
admet-423	30	42	profiles	profile	NOUN
admet-423	30	43	,	,	PUNCT
admet-423	30	44	(	(	PUNCT
admet-423	30	45	ii	ii	NOUN
admet-423	30	46	)	)	PUNCT
admet-423	30	47	pass	pass	VERB
admet-423	30	48	online	online	ADV
admet-423	30	49	[	[	X
admet-423	30	50	17	17	NUM
admet-423	30	51	]	]	PUNCT
admet-423	30	52	for	for	ADP
admet-423	30	53	envisaging	envisage	VERB
admet-423	30	54	their	their	PRON
admet-423	30	55	toxic	toxic	ADJ
admet-423	30	56	/	/	SYM
admet-423	30	57	side	side	NOUN
admet-423	30	58	effects	effect	NOUN
admet-423	30	59	,	,	PUNCT
admet-423	30	60	(	(	PUNCT
admet-423	30	61	iii	iii	NOUN
admet-423	30	62	)	)	PUNCT
admet-423	30	63	carcinopred	carcinopre	VERB
admet-423	30	64	-	-	PUNCT
admet-423	30	65	el	el	PROPN
admet-423	31	1	[	[	X
admet-423	31	2	18	18	NUM
admet-423	31	3	]	]	PUNCT
admet-423	31	4	to	to	PART
admet-423	31	5	predict	predict	VERB
admet-423	31	6	carcinogenicity	carcinogenicity	NOUN
admet-423	31	7	,	,	PUNCT
admet-423	31	8	pred	pre	VERB
admet-423	31	9	-	-	PUNCT
admet-423	31	10	herg4.0	herg4.0	NUM
admet-423	31	11	[	[	X
admet-423	31	12	19	19	NUM
admet-423	31	13	]	]	PUNCT
admet-423	31	14	to	to	PART
admet-423	31	15	assess	assess	VERB
admet-423	31	16	cardiotoxicity	cardiotoxicity	NOUN
admet-423	31	17	and	and	CCONJ
admet-423	31	18	endocrine	endocrine	NOUN
admet-423	31	19	disruptome	disruptome	NOUN
admet-423	32	1	[	[	X
admet-423	32	2	20	20	NUM
admet-423	32	3	]	]	PUNCT
admet-423	32	4	to	to	PART
admet-423	32	5	evaluate	evaluate	VERB
admet-423	32	6	their	their	PRON
admet-423	32	7	endocrine	endocrine	ADJ
admet-423	32	8	disruption	disruption	NOUN
admet-423	32	9	potential	potential	NOUN
admet-423	32	10	.	.	PUNCT
admet-423	33	1	these	these	DET
admet-423	33	2	tools	tool	NOUN
admet-423	33	3	have	have	AUX
admet-423	33	4	been	be	AUX
admet-423	33	5	selected	select	VERB
admet-423	33	6	among	among	ADP
admet-423	33	7	the	the	DET
admet-423	33	8	numerous	numerous	ADJ
admet-423	33	9	computational	computational	ADJ
admet-423	33	10	utilities	utility	NOUN
admet-423	33	11	destined	destine	VERB
admet-423	33	12	isvoran	isvoran	NOUN
admet-423	33	13	,	,	PUNCT
admet-423	33	14	ciorsac	ciorsac	NOUN
admet-423	33	15	,	,	PUNCT
admet-423	33	16	ostafe	ostafe	NOUN
admet-423	33	17	admet	admet	PROPN
admet-423	33	18	&	&	CCONJ
admet-423	33	19	dmpk	dmpk	PROPN
admet-423	33	20	5(3	5(3	NUM
admet-423	33	21	)	)	PUNCT
admet-423	33	22	(	(	PUNCT
admet-423	33	23	2017	2017	NUM
admet-423	33	24	)	)	PUNCT
admet-423	33	25	192	192	NUM
admet-423	33	26	-	-	SYM
admet-423	33	27	200	200	NUM
admet-423	33	28	194	194	NUM
admet-423	33	29	to	to	PART
admet-423	33	30	predict	predict	VERB
admet-423	33	31	the	the	DET
admet-423	33	32	adme	adme	NOUN
admet-423	33	33	-	-	PUNCT
admet-423	33	34	tox	tox	NOUN
admet-423	33	35	profile	profile	NOUN
admet-423	33	36	and	and	CCONJ
admet-423	33	37	pharmacokinetics	pharmacokinetic	NOUN
admet-423	33	38	because	because	SCONJ
admet-423	33	39	of	of	ADP
admet-423	33	40	their	their	PRON
admet-423	33	41	continuous	continuous	ADJ
admet-423	33	42	update	update	NOUN
admet-423	33	43	,	,	PUNCT
admet-423	33	44	accessibility	accessibility	NOUN
admet-423	33	45	by	by	ADP
admet-423	33	46	free	free	ADJ
admet-423	33	47	-	-	PUNCT
admet-423	33	48	login	login	NOUN
admet-423	33	49	on	on	ADP
admet-423	33	50	the	the	DET
admet-423	33	51	websites	website	NOUN
admet-423	33	52	and	and	CCONJ
admet-423	33	53	of	of	ADP
admet-423	33	54	their	their	PRON
admet-423	33	55	robustness	robustness	NOUN
admet-423	33	56	,	,	PUNCT
admet-423	33	57	accompanied	accompany	VERB
admet-423	33	58	by	by	ADP
admet-423	33	59	easy	easy	ADJ
admet-423	33	60	inputs	input	NOUN
admet-423	33	61	and	and	CCONJ
admet-423	33	62	interpretations	interpretation	NOUN
admet-423	33	63	.	.	PUNCT
admet-423	34	1	swissadme	swissadme	NOUN
admet-423	34	2	is	be	AUX
admet-423	34	3	a	a	DET
admet-423	34	4	free	free	ADJ
admet-423	34	5	available	available	ADJ
admet-423	34	6	on	on	ADP
admet-423	34	7	-	-	PUNCT
admet-423	34	8	line	line	NOUN
admet-423	34	9	computational	computational	ADJ
admet-423	34	10	tool	tool	NOUN
admet-423	34	11	allowing	allow	VERB
admet-423	34	12	online	online	ADJ
admet-423	34	13	computation	computation	NOUN
admet-423	34	14	of	of	ADP
admet-423	34	15	the	the	DET
admet-423	34	16	physicochemical	physicochemical	ADJ
admet-423	34	17	properties	property	NOUN
admet-423	34	18	of	of	ADP
admet-423	34	19	one	one	NUM
admet-423	34	20	or	or	CCONJ
admet-423	34	21	multiple	multiple	ADJ
admet-423	34	22	molecules	molecule	NOUN
admet-423	34	23	and	and	CCONJ
admet-423	34	24	prediction	prediction	NOUN
admet-423	34	25	of	of	ADP
admet-423	34	26	pharmacokinetics	pharmacokinetic	NOUN
admet-423	34	27	,	,	PUNCT
admet-423	34	28	drug	drug	NOUN
admet-423	34	29	-	-	PUNCT
admet-423	34	30	likeness	likeness	NOUN
admet-423	34	31	and	and	CCONJ
admet-423	34	32	medicinal	medicinal	ADJ
admet-423	34	33	chemistry	chemistry	NOUN
admet-423	34	34	friendliness	friendliness	NOUN
admet-423	34	35	[	[	X
admet-423	34	36	14	14	NUM
admet-423	34	37	]	]	PUNCT
admet-423	34	38	.	.	PUNCT
admet-423	35	1	it	it	PRON
admet-423	35	2	computes	compute	VERB
admet-423	35	3	for	for	ADP
admet-423	35	4	every	every	DET
admet-423	35	5	molecule	molecule	NOUN
admet-423	35	6	:	:	PUNCT
admet-423	35	7	the	the	DET
admet-423	35	8	chemical	chemical	NOUN
admet-423	35	9	structure	structure	NOUN
admet-423	35	10	,	,	PUNCT
admet-423	35	11	physicochemical	physicochemical	ADJ
admet-423	35	12	properties	property	NOUN
admet-423	35	13	(	(	PUNCT
admet-423	35	14	such	such	ADJ
admet-423	35	15	as	as	ADP
admet-423	35	16	molecular	molecular	ADJ
admet-423	35	17	weight	weight	NOUN
admet-423	35	18	,	,	PUNCT
admet-423	35	19	topological	topological	ADJ
admet-423	35	20	polar	polar	ADJ
admet-423	35	21	surface	surface	NOUN
admet-423	35	22	area	area	NOUN
admet-423	35	23	considering	consider	VERB
admet-423	35	24	phosphorous	phosphorous	ADJ
admet-423	35	25	and	and	CCONJ
admet-423	35	26	sulphur	sulphur	NOUN
admet-423	35	27	as	as	ADP
admet-423	35	28	polar	polar	ADJ
admet-423	35	29	atoms	atom	NOUN
admet-423	35	30	,	,	PUNCT
admet-423	35	31	molar	molar	ADJ
admet-423	35	32	refractivity	refractivity	NOUN
admet-423	35	33	,	,	PUNCT
admet-423	35	34	etc	etc	X
admet-423	35	35	)	)	PUNCT
admet-423	35	36	,	,	PUNCT
admet-423	35	37	lipophilicity	lipophilicity	NOUN
admet-423	35	38	,	,	PUNCT
admet-423	35	39	water	water	NOUN
admet-423	35	40	solubility	solubility	NOUN
admet-423	35	41	,	,	PUNCT
admet-423	35	42	bioavailability	bioavailability	NOUN
admet-423	35	43	radar	radar	NOUN
admet-423	35	44	,	,	PUNCT
admet-423	35	45	pharmacokinetics	pharmacokinetic	NOUN
admet-423	35	46	,	,	PUNCT
admet-423	35	47	the	the	DET
admet-423	35	48	skin	skin	NOUN
admet-423	35	49	permeability	permeability	NOUN
admet-423	35	50	coefficient	coefficient	NOUN
admet-423	35	51	,	,	PUNCT
admet-423	35	52	drug	drug	NOUN
admet-423	35	53	-	-	PUNCT
admet-423	35	54	likeness	likeness	NOUN
admet-423	35	55	and	and	CCONJ
admet-423	35	56	medicinal	medicinal	ADJ
admet-423	35	57	chemistry	chemistry	NOUN
admet-423	35	58	.	.	PUNCT
admet-423	36	1	lipophilicity	lipophilicity	NOUN
admet-423	36	2	is	be	AUX
admet-423	36	3	expressed	express	VERB
admet-423	36	4	by	by	ADP
admet-423	36	5	the	the	DET
admet-423	36	6	partition	partition	NOUN
admet-423	36	7	coefficient	coefficient	NOUN
admet-423	36	8	between	between	ADP
admet-423	36	9	n	n	NOUN
admet-423	36	10	-	-	PUNCT
admet-423	36	11	octanol	octanol	NOUN
admet-423	36	12	and	and	CCONJ
admet-423	36	13	water	water	NOUN
admet-423	36	14	(	(	PUNCT
admet-423	36	15	log	log	VERB
admet-423	36	16	po	po	PROPN
admet-423	36	17	/	/	SYM
admet-423	36	18	w	w	PROPN
admet-423	36	19	)	)	PUNCT
admet-423	36	20	which	which	PRON
admet-423	36	21	is	be	AUX
admet-423	36	22	computed	compute	VERB
admet-423	36	23	under	under	ADP
admet-423	36	24	swissadme	swissadme	NOUN
admet-423	36	25	tool	tool	NOUN
admet-423	36	26	by	by	ADP
admet-423	36	27	implementing	implement	VERB
admet-423	36	28	five	five	NUM
admet-423	36	29	different	different	ADJ
admet-423	36	30	methods	method	NOUN
admet-423	36	31	based	base	VERB
admet-423	36	32	on	on	ADP
admet-423	36	33	distinct	distinct	ADJ
admet-423	36	34	approaches	approach	NOUN
admet-423	36	35	and	and	CCONJ
admet-423	36	36	displaying	display	VERB
admet-423	36	37	both	both	CCONJ
admet-423	36	38	the	the	DET
admet-423	36	39	values	value	NOUN
admet-423	36	40	obtained	obtain	VERB
admet-423	36	41	using	use	VERB
admet-423	36	42	these	these	DET
admet-423	36	43	methods	method	NOUN
admet-423	36	44	and	and	CCONJ
admet-423	36	45	a	a	DET
admet-423	36	46	consensus	consensus	NOUN
admet-423	36	47	log	log	NOUN
admet-423	36	48	po	po	NOUN
admet-423	36	49	/	/	SYM
admet-423	36	50	w	w	PROPN
admet-423	36	51	as	as	ADP
admet-423	36	52	the	the	DET
admet-423	36	53	arithmetic	arithmetic	ADJ
admet-423	36	54	mean	mean	NOUN
admet-423	36	55	of	of	ADP
admet-423	36	56	the	the	DET
admet-423	36	57	predicted	predict	VERB
admet-423	36	58	values	value	NOUN
admet-423	36	59	.	.	PUNCT
admet-423	37	1	concerning	concern	VERB
admet-423	37	2	the	the	DET
admet-423	37	3	skin	skin	NOUN
admet-423	37	4	permeability	permeability	NOUN
admet-423	37	5	coefficient	coefficient	NOUN
admet-423	37	6	,	,	PUNCT
admet-423	37	7	it	it	PRON
admet-423	37	8	is	be	AUX
admet-423	37	9	expressed	express	VERB
admet-423	37	10	in	in	ADP
admet-423	37	11	log	log	NOUN
admet-423	37	12	units	unit	NOUN
admet-423	37	13	and	and	CCONJ
admet-423	37	14	a	a	DET
admet-423	37	15	more	more	ADV
admet-423	37	16	negative	negative	ADJ
admet-423	37	17	log	log	NOUN
admet-423	37	18	kp	kp	PROPN
admet-423	37	19	value	value	NOUN
admet-423	37	20	corresponds	correspond	VERB
admet-423	37	21	to	to	ADP
admet-423	37	22	a	a	DET
admet-423	37	23	less	less	ADV
admet-423	37	24	skin	skin	NOUN
admet-423	37	25	permeant	permeant	ADJ
admet-423	37	26	molecule	molecule	NOUN
admet-423	37	27	.	.	PUNCT
admet-423	38	1	as	as	ADP
admet-423	38	2	an	an	DET
admet-423	38	3	example	example	NOUN
admet-423	38	4	,	,	PUNCT
admet-423	38	5	the	the	DET
admet-423	38	6	skin	skin	NOUN
admet-423	38	7	permeability	permeability	NOUN
admet-423	38	8	coefficient	coefficient	NOUN
admet-423	38	9	of	of	ADP
admet-423	38	10	diclofenac	diclofenac	NOUN
admet-423	38	11	(	(	PUNCT
admet-423	38	12	that	that	PRON
admet-423	38	13	is	be	AUX
admet-423	38	14	known	know	VERB
admet-423	38	15	to	to	PART
admet-423	38	16	have	have	VERB
admet-423	38	17	a	a	DET
admet-423	38	18	good	good	ADJ
admet-423	38	19	skin	skin	NOUN
admet-423	38	20	permeability	permeability	NOUN
admet-423	38	21	)	)	PUNCT
admet-423	38	22	is	be	AUX
admet-423	38	23	predicted	predict	VERB
admet-423	38	24	as	as	ADP
admet-423	38	25	log	log	NOUN
admet-423	38	26	kp	kp	NOUN
admet-423	38	27	=	=	PUNCT
admet-423	38	28	-4.96	-4.96	NUM
admet-423	38	29	cm	cm	PROPN
admet-423	38	30	/	/	SYM
admet-423	38	31	s	s	NOUN
admet-423	38	32	and	and	CCONJ
admet-423	38	33	those	those	PRON
admet-423	38	34	of	of	ADP
admet-423	38	35	ouabain	ouabain	NOUN
admet-423	38	36	(	(	PUNCT
admet-423	38	37	that	that	PRON
admet-423	38	38	is	be	AUX
admet-423	38	39	not	not	PART
admet-423	38	40	able	able	ADJ
admet-423	38	41	to	to	PART
admet-423	38	42	penetrate	penetrate	VERB
admet-423	38	43	the	the	DET
admet-423	38	44	skin	skin	NOUN
admet-423	38	45	)	)	PUNCT
admet-423	38	46	is	be	AUX
admet-423	38	47	predicted	predict	VERB
admet-423	38	48	as	as	ADP
admet-423	38	49	log	log	NOUN
admet-423	38	50	kp	kp	NOUN
admet-423	39	1	=	=	PUNCT
admet-423	39	2	-10.94	-10.94	PROPN
admet-423	39	3	cm	cm	NOUN
admet-423	39	4	/	/	SYM
admet-423	39	5	s	s	PART
admet-423	40	1	[	[	X
admet-423	40	2	21	21	NUM
admet-423	40	3	]	]	PUNCT
admet-423	40	4	.	.	PUNCT
admet-423	41	1	when	when	SCONJ
admet-423	41	2	displaying	display	VERB
admet-423	41	3	the	the	DET
admet-423	41	4	bioavailability	bioavailability	NOUN
admet-423	41	5	radar	radar	NOUN
admet-423	41	6	,	,	PUNCT
admet-423	41	7	six	six	NUM
admet-423	41	8	physicochemical	physicochemical	ADJ
admet-423	41	9	properties	property	NOUN
admet-423	41	10	are	be	AUX
admet-423	41	11	taken	take	VERB
admet-423	41	12	into	into	ADP
admet-423	41	13	account	account	NOUN
admet-423	41	14	:	:	PUNCT
admet-423	41	15	size	size	NOUN
admet-423	41	16	,	,	PUNCT
admet-423	41	17	polarity	polarity	NOUN
admet-423	41	18	,	,	PUNCT
admet-423	41	19	lipophilicity	lipophilicity	PROPN
admet-423	41	20	,	,	PUNCT
admet-423	41	21	solubility	solubility	NOUN
admet-423	41	22	,	,	PUNCT
admet-423	41	23	flexibility	flexibility	NOUN
admet-423	41	24	and	and	CCONJ
admet-423	41	25	saturation	saturation	NOUN
admet-423	41	26	.	.	PUNCT
admet-423	42	1	concerning	concern	VERB
admet-423	42	2	the	the	DET
admet-423	42	3	pharmacokinetics	pharmacokinetic	NOUN
admet-423	42	4	,	,	PUNCT
admet-423	42	5	drug	drug	NOUN
admet-423	42	6	-	-	PUNCT
admet-423	42	7	likeness	likeness	NOUN
admet-423	42	8	and	and	CCONJ
admet-423	42	9	medicinal	medicinal	ADJ
admet-423	42	10	chemistry	chemistry	NOUN
admet-423	42	11	predictions	prediction	NOUN
admet-423	42	12	,	,	PUNCT
admet-423	42	13	the	the	DET
admet-423	42	14	swissadme	swissadme	PROPN
admet-423	42	15	classifiers	classifier	NOUN
admet-423	42	16	reveal	reveal	VERB
admet-423	42	17	a	a	DET
admet-423	42	18	similar	similar	ADJ
admet-423	42	19	accuracy	accuracy	NOUN
admet-423	42	20	of	of	ADP
admet-423	42	21	prediction	prediction	NOUN
admet-423	42	22	as	as	ADP
admet-423	42	23	the	the	DET
admet-423	42	24	other	other	ADJ
admet-423	42	25	tools	tool	NOUN
admet-423	42	26	,	,	PUNCT
admet-423	42	27	demonstrating	demonstrate	VERB
admet-423	42	28	strong	strong	ADJ
admet-423	42	29	correlation	correlation	NOUN
admet-423	42	30	between	between	ADP
admet-423	42	31	predicted	predict	VERB
admet-423	42	32	and	and	CCONJ
admet-423	42	33	experimental	experimental	ADJ
admet-423	42	34	values	value	NOUN
admet-423	42	35	for	for	ADP
admet-423	42	36	molecules	molecule	NOUN
admet-423	42	37	belonging	belong	VERB
admet-423	42	38	to	to	ADP
admet-423	42	39	the	the	DET
admet-423	42	40	training	training	NOUN
admet-423	42	41	sets	set	NOUN
admet-423	42	42	[	[	X
admet-423	42	43	14	14	NUM
admet-423	42	44	]	]	PUNCT
admet-423	42	45	.	.	PUNCT
admet-423	43	1	fadrugs	fadrugs	PROPN
admet-423	43	2	is	be	AUX
admet-423	43	3	another	another	DET
admet-423	43	4	free	free	ADJ
admet-423	43	5	available	available	ADJ
admet-423	43	6	online	online	ADJ
admet-423	43	7	computational	computational	ADJ
admet-423	43	8	toll	toll	NOUN
admet-423	43	9	allowing	allow	VERB
admet-423	43	10	analysing	analysing	NOUN
admet-423	43	11	or	or	CCONJ
admet-423	43	12	filtering	filtering	NOUN
admet-423	43	13	of	of	ADP
admet-423	43	14	molecules	molecule	NOUN
admet-423	43	15	with	with	ADP
admet-423	43	16	eight	eight	NUM
admet-423	43	17	predefined	predefine	VERB
admet-423	43	18	physicochemical	physicochemical	ADJ
admet-423	43	19	filters	filter	NOUN
admet-423	43	20	based	base	VERB
admet-423	43	21	on	on	ADP
admet-423	43	22	several	several	ADJ
admet-423	43	23	simple	simple	ADJ
admet-423	43	24	adme	adme	NOUN
admet-423	43	25	-	-	PUNCT
admet-423	43	26	tox	tox	NOUN
admet-423	43	27	rules	rule	NOUN
admet-423	43	28	[	[	X
admet-423	43	29	15	15	NUM
admet-423	43	30	,	,	PUNCT
admet-423	43	31	16	16	NUM
admet-423	43	32	]	]	PUNCT
admet-423	43	33	.	.	PUNCT
admet-423	44	1	this	this	DET
admet-423	44	2	tool	tool	NOUN
admet-423	44	3	allows	allow	VERB
admet-423	44	4	the	the	DET
admet-423	44	5	following	follow	VERB
admet-423	44	6	procedures	procedure	NOUN
admet-423	44	7	:	:	PUNCT
admet-423	44	8	(	(	PUNCT
admet-423	44	9	i	i	NOUN
admet-423	44	10	)	)	PUNCT
admet-423	44	11	a	a	DET
admet-423	44	12	data	data	NOUN
admet-423	44	13	curation	curation	NOUN
admet-423	44	14	stage	stage	NOUN
admet-423	44	15	by	by	ADP
admet-423	44	16	desalting	desalt	VERB
admet-423	44	17	molecules	molecule	NOUN
admet-423	44	18	and	and	CCONJ
admet-423	44	19	removing	remove	VERB
admet-423	44	20	large	large	ADJ
admet-423	44	21	molecules	molecule	NOUN
admet-423	44	22	and	and	CCONJ
admet-423	44	23	compounds	compound	NOUN
admet-423	44	24	containing	contain	VERB
admet-423	44	25	some	some	DET
admet-423	44	26	types	type	NOUN
admet-423	44	27	of	of	ADP
admet-423	44	28	inorganic	inorganic	ADJ
admet-423	44	29	atoms	atom	NOUN
admet-423	44	30	or	or	CCONJ
admet-423	44	31	duplicates	duplicate	NOUN
admet-423	44	32	,	,	PUNCT
admet-423	44	33	(	(	PUNCT
admet-423	44	34	ii	ii	NOUN
admet-423	44	35	)	)	PUNCT
admet-423	44	36	the	the	DET
admet-423	44	37	computation	computation	NOUN
admet-423	44	38	of	of	ADP
admet-423	44	39	several	several	ADJ
admet-423	44	40	physicochemical	physicochemical	ADJ
admet-423	44	41	properties	property	NOUN
admet-423	44	42	of	of	ADP
admet-423	44	43	molecules	molecule	NOUN
admet-423	44	44	and	and	CCONJ
admet-423	44	45	their	their	PRON
admet-423	44	46	filtering	filtering	NOUN
admet-423	44	47	considering	consider	VERB
admet-423	44	48	several	several	ADJ
admet-423	44	49	adme	adme	NOUN
admet-423	44	50	-	-	PUNCT
admet-423	44	51	tox	tox	NOUN
admet-423	44	52	rules	rule	NOUN
admet-423	44	53	,	,	PUNCT
admet-423	44	54	(	(	PUNCT
admet-423	44	55	iii	iii	X
admet-423	44	56	)	)	PUNCT
admet-423	44	57	the	the	DET
admet-423	44	58	detection	detection	NOUN
admet-423	44	59	of	of	ADP
admet-423	44	60	potential	potential	ADJ
admet-423	44	61	toxic	toxic	ADJ
admet-423	44	62	groups	group	NOUN
admet-423	44	63	,	,	PUNCT
admet-423	44	64	aggregators	aggregator	NOUN
admet-423	44	65	and	and	CCONJ
admet-423	44	66	pains	pain	NOUN
admet-423	44	67	[	[	X
admet-423	44	68	15	15	NUM
admet-423	44	69	,	,	PUNCT
admet-423	44	70	16	16	NUM
admet-423	44	71	]	]	PUNCT
admet-423	44	72	.	.	PUNCT
admet-423	45	1	fafdrugs	fafdrug	NOUN
admet-423	45	2	tool	tool	PROPN
admet-423	45	3	has	have	AUX
admet-423	45	4	been	be	AUX
admet-423	45	5	validated	validate	VERB
admet-423	45	6	by	by	ADP
admet-423	45	7	using	use	VERB
admet-423	45	8	a	a	DET
admet-423	45	9	list	list	NOUN
admet-423	45	10	of	of	ADP
admet-423	45	11	40	40	NUM
admet-423	45	12	documented	document	VERB
admet-423	45	13	toxicophores	toxicophore	NOUN
admet-423	45	14	and	and	CCONJ
admet-423	45	15	a	a	DET
admet-423	45	16	list	list	NOUN
admet-423	45	17	of	of	ADP
admet-423	45	18	778	778	NUM
admet-423	45	19	annotated	annotate	VERB
admet-423	45	20	oral	oral	ADJ
admet-423	45	21	drugs	drug	NOUN
admet-423	45	22	used	use	VERB
admet-423	45	23	in	in	ADP
admet-423	45	24	19	19	NUM
admet-423	45	25	therapeutic	therapeutic	ADJ
admet-423	45	26	areas	area	NOUN
admet-423	45	27	.	.	PUNCT
admet-423	46	1	an	an	DET
admet-423	46	2	alert	alert	NOUN
admet-423	46	3	was	be	AUX
admet-423	46	4	detected	detect	VERB
admet-423	46	5	in	in	ADP
admet-423	46	6	36	36	NUM
admet-423	46	7	among	among	ADP
admet-423	46	8	the	the	DET
admet-423	46	9	40	40	NUM
admet-423	46	10	toxicophores	toxicophore	NOUN
admet-423	46	11	with	with	ADP
admet-423	46	12	100	100	NUM
admet-423	46	13	%	%	NOUN
admet-423	46	14	efficacy	efficacy	NOUN
admet-423	46	15	with	with	ADP
admet-423	46	16	regard	regard	NOUN
admet-423	46	17	to	to	ADP
admet-423	46	18	the	the	DET
admet-423	46	19	nature	nature	NOUN
admet-423	46	20	of	of	ADP
admet-423	46	21	the	the	DET
admet-423	46	22	alerts	alert	NOUN
admet-423	46	23	and	and	CCONJ
admet-423	46	24	among	among	ADP
admet-423	46	25	the	the	DET
admet-423	46	26	778	778	NUM
admet-423	46	27	drugs	drug	NOUN
admet-423	46	28	,	,	PUNCT
admet-423	46	29	81	81	NUM
admet-423	46	30	%	%	NOUN
admet-423	46	31	satisfied	satisfy	VERB
admet-423	46	32	the	the	DET
admet-423	46	33	rules	rule	NOUN
admet-423	46	34	[	[	X
admet-423	46	35	15	15	NUM
admet-423	46	36	,	,	PUNCT
admet-423	46	37	16	16	NUM
admet-423	46	38	]	]	PUNCT
admet-423	46	39	.	.	PUNCT
admet-423	47	1	prediction	prediction	NOUN
admet-423	47	2	of	of	ADP
admet-423	47	3	activity	activity	NOUN
admet-423	47	4	spectra	spectra	NOUN
admet-423	47	5	of	of	ADP
admet-423	47	6	substances	substance	NOUN
admet-423	47	7	(	(	PUNCT
admet-423	47	8	pass	pass	NOUN
admet-423	47	9	)	)	PUNCT
admet-423	47	10	is	be	AUX
admet-423	47	11	a	a	DET
admet-423	47	12	computational	computational	ADJ
admet-423	47	13	tool	tool	NOUN
admet-423	47	14	allowing	allow	VERB
admet-423	47	15	prediction	prediction	NOUN
admet-423	47	16	of	of	ADP
admet-423	47	17	biological	biological	ADJ
admet-423	47	18	activity	activity	NOUN
admet-423	47	19	and/or	and/or	CCONJ
admet-423	47	20	toxic	toxic	ADJ
admet-423	47	21	and	and	CCONJ
admet-423	47	22	side	side	NOUN
admet-423	47	23	effects	effect	NOUN
admet-423	47	24	of	of	ADP
admet-423	47	25	a	a	DET
admet-423	47	26	chemical	chemical	NOUN
admet-423	47	27	compound	compound	NOUN
admet-423	47	28	starting	start	VERB
admet-423	47	29	from	from	ADP
admet-423	47	30	its	its	PRON
admet-423	47	31	structural	structural	ADJ
admet-423	47	32	formula	formula	NOUN
admet-423	47	33	,	,	PUNCT
admet-423	47	34	the	the	DET
admet-423	47	35	mean	mean	ADJ
admet-423	47	36	accuracy	accuracy	NOUN
admet-423	47	37	of	of	ADP
admet-423	47	38	prediction	prediction	NOUN
admet-423	47	39	being	be	AUX
admet-423	47	40	about	about	ADV
admet-423	47	41	90	90	NUM
admet-423	47	42	%	%	NOUN
admet-423	47	43	[	[	X
admet-423	47	44	17	17	NUM
admet-423	47	45	]	]	PUNCT
admet-423	47	46	.	.	PUNCT
admet-423	48	1	pass	pass	VERB
admet-423	48	2	algorithm	algorithm	NOUN
admet-423	48	3	estimates	estimate	VERB
admet-423	48	4	the	the	DET
admet-423	48	5	probability	probability	NOUN
admet-423	48	6	that	that	SCONJ
admet-423	48	7	the	the	DET
admet-423	48	8	investigated	investigate	VERB
admet-423	48	9	compound	compound	NOUN
admet-423	48	10	belongs	belong	VERB
admet-423	48	11	to	to	ADP
admet-423	48	12	a	a	DET
admet-423	48	13	particular	particular	ADJ
admet-423	48	14	class	class	NOUN
admet-423	48	15	of	of	ADP
admet-423	48	16	active	active	ADJ
admet-423	48	17	compounds	compound	NOUN
admet-423	48	18	(	(	PUNCT
admet-423	48	19	pa	pa	NOUN
admet-423	48	20	)	)	PUNCT
admet-423	48	21	or	or	CCONJ
admet-423	48	22	inactive	inactive	ADJ
admet-423	48	23	compounds	compound	NOUN
admet-423	48	24	(	(	PUNCT
admet-423	48	25	pi	pi	NOUN
admet-423	48	26	)	)	PUNCT
admet-423	48	27	.	.	PUNCT
admet-423	49	1	the	the	DET
admet-423	49	2	value	value	NOUN
admet-423	49	3	of	of	ADP
admet-423	49	4	pa	pa	PROPN
admet-423	49	5	reveals	reveal	VERB
admet-423	49	6	the	the	DET
admet-423	49	7	similarity	similarity	NOUN
admet-423	49	8	of	of	ADP
admet-423	49	9	the	the	DET
admet-423	49	10	molecule	molecule	NOUN
admet-423	49	11	under	under	ADP
admet-423	49	12	investigation	investigation	NOUN
admet-423	49	13	with	with	ADP
admet-423	49	14	the	the	DET
admet-423	49	15	structures	structure	NOUN
admet-423	49	16	of	of	ADP
admet-423	49	17	those	those	DET
admet-423	49	18	molecules	molecule	NOUN
admet-423	49	19	within	within	ADP
admet-423	49	20	the	the	DET
admet-423	49	21	training	training	NOUN
admet-423	49	22	set	set	NOUN
admet-423	49	23	which	which	PRON
admet-423	49	24	are	be	AUX
admet-423	49	25	the	the	DET
admet-423	49	26	most	most	ADV
admet-423	49	27	typical	typical	ADJ
admet-423	49	28	in	in	ADP
admet-423	49	29	a	a	DET
admet-423	49	30	subset	subset	NOUN
admet-423	49	31	of	of	ADP
admet-423	49	32	“	"	PUNCT
admet-423	49	33	actives	active	NOUN
admet-423	49	34	”	"	PUNCT
admet-423	49	35	.	.	PUNCT
admet-423	50	1	correspondingly	correspondingly	ADV
admet-423	50	2	,	,	PUNCT
admet-423	50	3	pi	pi	NOUN
admet-423	50	4	reflects	reflect	VERB
admet-423	50	5	the	the	DET
admet-423	50	6	similarity	similarity	NOUN
admet-423	50	7	of	of	ADP
admet-423	50	8	the	the	DET
admet-423	50	9	investigated	investigate	VERB
admet-423	50	10	compound	compound	NOUN
admet-423	50	11	with	with	ADP
admet-423	50	12	the	the	DET
admet-423	50	13	molecules	molecule	NOUN
admet-423	50	14	within	within	ADP
admet-423	50	15	the	the	DET
admet-423	50	16	training	training	NOUN
admet-423	50	17	set	set	NOUN
admet-423	50	18	that	that	PRON
admet-423	50	19	belongs	belong	VERB
admet-423	50	20	to	to	ADP
admet-423	50	21	the	the	DET
admet-423	50	22	subset	subset	NOUN
admet-423	50	23	of	of	ADP
admet-423	50	24	“	"	PUNCT
admet-423	50	25	inactive	inactive	ADJ
admet-423	50	26	”	"	PUNCT
admet-423	50	27	.	.	PUNCT
admet-423	51	1	the	the	DET
admet-423	51	2	two	two	NUM
admet-423	51	3	probabilities	probability	NOUN
admet-423	51	4	values	value	NOUN
admet-423	51	5	(	(	PUNCT
admet-423	51	6	pa	pa	PROPN
admet-423	51	7	and	and	CCONJ
admet-423	51	8	pi	pi	NOUN
admet-423	51	9	)	)	PUNCT
admet-423	51	10	vary	vary	VERB
admet-423	51	11	from	from	ADP
admet-423	51	12	0	0	NUM
admet-423	51	13	to	to	ADP
admet-423	51	14	1	1	NUM
admet-423	51	15	and	and	CCONJ
admet-423	51	16	are	be	AUX
admet-423	51	17	independent	independent	ADJ
admet-423	51	18	.	.	PUNCT
admet-423	52	1	only	only	ADV
admet-423	52	2	those	those	DET
admet-423	52	3	activities	activity	NOUN
admet-423	52	4	with	with	ADP
admet-423	52	5	pa	pa	PROPN
admet-423	52	6	>	>	X
admet-423	52	7	pi	pi	PROPN
admet-423	52	8	are	be	AUX
admet-423	52	9	considered	consider	VERB
admet-423	52	10	as	as	ADP
admet-423	52	11	promising	promise	VERB
admet-423	52	12	for	for	ADP
admet-423	52	13	a	a	DET
admet-423	52	14	particular	particular	ADJ
admet-423	52	15	compound	compound	NOUN
admet-423	52	16	and	and	CCONJ
admet-423	52	17	a	a	DET
admet-423	52	18	good	good	ADJ
admet-423	52	19	accuracy	accuracy	NOUN
admet-423	52	20	of	of	ADP
admet-423	52	21	prediction	prediction	NOUN
admet-423	52	22	is	be	AUX
admet-423	52	23	obtained	obtain	VERB
admet-423	52	24	when	when	SCONJ
admet-423	52	25	pa	pa	PROPN
admet-423	52	26	>	>	X
admet-423	52	27	0.7	0.7	NUM
admet-423	53	1	[	[	X
admet-423	53	2	17	17	NUM
admet-423	53	3	]	]	PUNCT
admet-423	53	4	.	.	PUNCT
admet-423	54	1	carcinopred	carcinopre	VERB
admet-423	54	2	-	-	PUNCT
admet-423	54	3	el	el	PROPN
admet-423	54	4	is	be	AUX
admet-423	54	5	a	a	DET
admet-423	54	6	free	free	ADJ
admet-423	54	7	prediction	prediction	NOUN
admet-423	54	8	online	online	NOUN
admet-423	54	9	server	server	NOUN
admet-423	54	10	based	base	VERB
admet-423	54	11	on	on	ADP
admet-423	54	12	twelve	twelve	NUM
admet-423	54	13	different	different	ADJ
admet-423	54	14	molecular	molecular	ADJ
admet-423	54	15	fingerprints	fingerprint	NOUN
admet-423	54	16	and	and	CCONJ
admet-423	54	17	ensemble	ensemble	ADJ
admet-423	54	18	machine	machine	NOUN
admet-423	54	19	learning	learning	NOUN
admet-423	54	20	methods	method	NOUN
admet-423	54	21	allowing	allow	VERB
admet-423	54	22	identification	identification	NOUN
admet-423	54	23	of	of	ADP
admet-423	54	24	the	the	DET
admet-423	54	25	structural	structural	ADJ
admet-423	54	26	features	feature	NOUN
admet-423	54	27	related	relate	VERB
admet-423	54	28	to	to	ADP
admet-423	54	29	carcinogenic	carcinogenic	ADJ
admet-423	54	30	effects	effect	NOUN
admet-423	54	31	of	of	ADP
admet-423	54	32	organic	organic	ADJ
admet-423	54	33	compounds	compound	NOUN
admet-423	54	34	[	[	X
admet-423	54	35	18	18	NUM
admet-423	54	36	]	]	PUNCT
admet-423	54	37	.	.	PUNCT
admet-423	55	1	it	it	PRON
admet-423	55	2	uses	use	VERB
admet-423	55	3	1003	1003	NUM
admet-423	55	4	compounds	compound	NOUN
admet-423	55	5	with	with	ADP
admet-423	55	6	known	know	VERB
admet-423	55	7	carcinogenicity	carcinogenicity	NOUN
admet-423	55	8	against	against	ADP
admet-423	55	9	rats	rat	NOUN
admet-423	55	10	(	(	PUNCT
admet-423	55	11	494	494	NUM
admet-423	55	12	carcinogens	carcinogen	NOUN
admet-423	55	13	and	and	CCONJ
admet-423	55	14	509	509	NUM
admet-423	55	15	non	non	ADJ
admet-423	55	16	-	-	ADJ
admet-423	55	17	carcinogens	carcinogen	NOUN
admet-423	55	18	)	)	PUNCT
admet-423	55	19	that	that	PRON
admet-423	55	20	are	be	AUX
admet-423	55	21	found	find	VERB
admet-423	55	22	in	in	ADP
admet-423	55	23	the	the	DET
admet-423	55	24	carcinogenic	carcinogenic	ADJ
admet-423	55	25	potency	potency	NOUN
admet-423	55	26	admet	admet	NOUN
admet-423	55	27	&	&	CCONJ
admet-423	55	28	dmpk	dmpk	PROPN
admet-423	55	29	5(3	5(3	NUM
admet-423	55	30	)	)	PUNCT
admet-423	55	31	(	(	PUNCT
admet-423	55	32	2017	2017	NUM
admet-423	55	33	)	)	PUNCT
admet-423	55	34	192	192	NUM
admet-423	55	35	-	-	SYM
admet-423	55	36	200	200	NUM
admet-423	55	37	admet	admet	NOUN
admet-423	55	38	of	of	ADP
admet-423	55	39	chitosan	chitosan	NOUN
admet-423	55	40	derivatives	derivative	NOUN
admet-423	55	41	doi	doi	NOUN
admet-423	55	42	:	:	PUNCT
admet-423	55	43	10.5599	10.5599	NUM
admet-423	55	44	/	/	SYM
admet-423	55	45	admet.5.3.423	admet.5.3.423	PRON
admet-423	55	46	195	195	NUM
admet-423	55	47	database	database	NOUN
admet-423	55	48	[	[	X
admet-423	55	49	22	22	NUM
admet-423	55	50	]	]	PUNCT
admet-423	55	51	as	as	SCONJ
admet-423	55	52	the	the	DET
admet-423	55	53	training	training	NOUN
admet-423	55	54	dataset	dataset	VERB
admet-423	55	55	to	to	PART
admet-423	55	56	develop	develop	VERB
admet-423	55	57	models	model	NOUN
admet-423	55	58	for	for	ADP
admet-423	55	59	predicting	predict	VERB
admet-423	55	60	the	the	DET
admet-423	55	61	carcinogenicity	carcinogenicity	NOUN
admet-423	55	62	and	and	CCONJ
admet-423	55	63	an	an	DET
admet-423	55	64	external	external	ADJ
admet-423	55	65	validation	validation	NOUN
admet-423	55	66	dataset	dataset	NOUN
admet-423	55	67	of	of	ADP
admet-423	55	68	40	40	NUM
admet-423	55	69	compounds	compound	NOUN
admet-423	55	70	(	(	PUNCT
admet-423	55	71	23	23	NUM
admet-423	55	72	carcinogens	carcinogen	NOUN
admet-423	55	73	and	and	CCONJ
admet-423	55	74	17	17	NUM
admet-423	55	75	non	non	ADJ
admet-423	55	76	-	-	NOUN
admet-423	55	77	carcinogens	carcinogen	NOUN
admet-423	55	78	)	)	PUNCT
admet-423	55	79	from	from	ADP
admet-423	55	80	the	the	DET
admet-423	55	81	isscan	isscan	ADJ
admet-423	55	82	database	database	NOUN
admet-423	56	1	[	[	X
admet-423	56	2	23	23	NUM
admet-423	56	3	]	]	PUNCT
admet-423	56	4	that	that	PRON
admet-423	56	5	do	do	AUX
admet-423	56	6	not	not	PART
admet-423	56	7	duplicate	duplicate	VERB
admet-423	56	8	the	the	DET
admet-423	56	9	training	training	NOUN
admet-423	56	10	dataset	dataset	NOUN
admet-423	56	11	and	and	CCONJ
admet-423	56	12	the	the	DET
admet-423	56	13	accuracy	accuracy	NOUN
admet-423	56	14	of	of	ADP
admet-423	56	15	prediction	prediction	NOUN
admet-423	56	16	is	be	AUX
admet-423	56	17	about	about	ADV
admet-423	56	18	70	70	NUM
admet-423	56	19	%	%	NOUN
admet-423	56	20	.	.	PUNCT
admet-423	57	1	pred	pre	VERB
admet-423	57	2	-	-	PUNCT
admet-423	57	3	herg	herg	PROPN
admet-423	57	4	is	be	AUX
admet-423	57	5	a	a	DET
admet-423	57	6	free	free	ADJ
admet-423	57	7	accessible	accessible	ADJ
admet-423	57	8	web	web	NOUN
admet-423	57	9	tool	tool	NOUN
admet-423	57	10	that	that	PRON
admet-423	57	11	builds	build	VERB
admet-423	57	12	predictive	predictive	ADJ
admet-423	57	13	qsar	qsar	NOUN
admet-423	57	14	(	(	PUNCT
admet-423	57	15	quantitative	quantitative	ADJ
admet-423	57	16	structure	structure	NOUN
admet-423	57	17	activity	activity	NOUN
admet-423	57	18	relationship	relationship	NOUN
admet-423	57	19	)	)	PUNCT
admet-423	57	20	models	model	NOUN
admet-423	57	21	of	of	ADP
admet-423	57	22	herg	herg	PROPN
admet-423	57	23	k+	k+	PROPN
admet-423	57	24	channel	channel	NOUN
admet-423	57	25	blockage	blockage	NOUN
admet-423	57	26	.	.	PUNCT
admet-423	58	1	the	the	DET
admet-423	58	2	predictions	prediction	NOUN
admet-423	58	3	are	be	AUX
admet-423	58	4	built	build	VERB
admet-423	58	5	using	use	VERB
admet-423	58	6	the	the	DET
admet-423	58	7	largest	large	ADJ
admet-423	58	8	free	free	ADJ
admet-423	58	9	available	available	ADJ
admet-423	58	10	dataset	dataset	NOUN
admet-423	58	11	of	of	ADP
admet-423	58	12	structurally	structurally	ADV
admet-423	58	13	diverse	diverse	ADJ
admet-423	58	14	compound	compound	NOUN
admet-423	58	15	with	with	ADP
admet-423	58	16	16932	16932	NUM
admet-423	58	17	associated	associated	ADJ
admet-423	58	18	bioactivity	bioactivity	NOUN
admet-423	58	19	records	record	NOUN
admet-423	58	20	for	for	ADP
admet-423	58	21	the	the	DET
admet-423	58	22	herg	herg	PROPN
admet-423	58	23	liability	liability	NOUN
admet-423	58	24	that	that	PRON
admet-423	58	25	are	be	AUX
admet-423	58	26	contained	contain	VERB
admet-423	58	27	in	in	ADP
admet-423	58	28	the	the	DET
admet-423	58	29	chembl	chembl	NOUN
admet-423	58	30	database	database	NOUN
admet-423	59	1	[	[	X
admet-423	59	2	24	24	NUM
admet-423	59	3	]	]	PUNCT
admet-423	59	4	with	with	ADP
admet-423	59	5	an	an	DET
admet-423	59	6	accuracy	accuracy	NOUN
admet-423	59	7	up	up	ADP
admet-423	59	8	to	to	PART
admet-423	59	9	89	89	NUM
admet-423	59	10	%	%	NOUN
admet-423	59	11	[	[	X
admet-423	59	12	19	19	NUM
admet-423	59	13	]	]	PUNCT
admet-423	59	14	.	.	PUNCT
admet-423	60	1	endocrine	endocrine	PROPN
admet-423	60	2	disruptome	disruptome	NOUN
admet-423	60	3	is	be	AUX
admet-423	60	4	a	a	DET
admet-423	60	5	free	free	ADJ
admet-423	60	6	web	web	NOUN
admet-423	60	7	service	service	NOUN
admet-423	60	8	able	able	ADJ
admet-423	60	9	to	to	PART
admet-423	60	10	assess	assess	VERB
admet-423	60	11	the	the	DET
admet-423	60	12	endocrine	endocrine	ADJ
admet-423	60	13	disruption	disruption	NOUN
admet-423	60	14	potential	potential	NOUN
admet-423	60	15	of	of	ADP
admet-423	60	16	a	a	DET
admet-423	60	17	chemical	chemical	NOUN
admet-423	60	18	compound	compound	NOUN
admet-423	60	19	by	by	ADP
admet-423	60	20	using	use	VERB
admet-423	60	21	the	the	DET
admet-423	60	22	molecular	molecular	ADJ
admet-423	60	23	docking	docking	NOUN
admet-423	60	24	method	method	NOUN
admet-423	60	25	based	base	VERB
admet-423	60	26	on	on	ADP
admet-423	60	27	autodock	autodock	PROPN
admet-423	60	28	vina	vina	PROPN
admet-423	60	29	algorithm	algorithm	PROPN
admet-423	60	30	[	[	X
admet-423	60	31	25	25	NUM
admet-423	60	32	]	]	PUNCT
admet-423	60	33	.	.	PUNCT
admet-423	61	1	investigated	investigate	VERB
admet-423	61	2	compound	compound	NOUN
admet-423	61	3	is	be	AUX
admet-423	61	4	docked	dock	VERB
admet-423	61	5	to	to	ADP
admet-423	61	6	18	18	NUM
admet-423	61	7	crystallographic	crystallographic	ADJ
admet-423	61	8	structures	structure	NOUN
admet-423	61	9	available	available	ADJ
admet-423	61	10	in	in	ADP
admet-423	61	11	the	the	DET
admet-423	61	12	protein	protein	NOUN
admet-423	61	13	data	datum	NOUN
admet-423	61	14	bank	bank	NOUN
admet-423	62	1	[	[	X
admet-423	62	2	26	26	NUM
admet-423	62	3	]	]	PUNCT
admet-423	62	4	for	for	ADP
admet-423	62	5	14	14	NUM
admet-423	62	6	distinct	distinct	ADJ
admet-423	62	7	human	human	ADJ
admet-423	62	8	nuclear	nuclear	ADJ
admet-423	62	9	receptors	receptor	NOUN
admet-423	62	10	:	:	PUNCT
admet-423	62	11	androgen	androgen	NOUN
admet-423	62	12	receptor	receptor	NOUN
admet-423	62	13	;	;	PUNCT
admet-423	62	14	estrogen	estrogen	NOUN
admet-423	62	15	receptors	receptor	NOUN
admet-423	62	16	α	α	NOUN
admet-423	62	17	and	and	CCONJ
admet-423	62	18	β	β	NOUN
admet-423	62	19	;	;	PUNCT
admet-423	62	20	glucocorticoid	glucocorticoid	ADJ
admet-423	62	21	receptor	receptor	NOUN
admet-423	62	22	;	;	PUNCT
admet-423	62	23	liver	liver	NOUN
admet-423	62	24	x	x	NOUN
admet-423	62	25	receptors	receptor	NOUN
admet-423	62	26	α	α	NOUN
admet-423	62	27	and	and	CCONJ
admet-423	62	28	β	β	NOUN
admet-423	62	29	;	;	PUNCT
admet-423	62	30	mineralocorticoid	mineralocorticoid	NOUN
admet-423	62	31	receptor	receptor	NOUN
admet-423	62	32	;	;	PUNCT
admet-423	62	33	peroxisome	peroxisome	VERB
admet-423	62	34	proliferator	proliferator	NOUN
admet-423	62	35	activated	activate	VERB
admet-423	62	36	receptors	receptor	NOUN
admet-423	62	37	α	α	NOUN
admet-423	62	38	,	,	PUNCT
admet-423	62	39	β	β	X
admet-423	62	40	/	/	SYM
admet-423	62	41	δ	δ	PROPN
admet-423	62	42	,	,	PUNCT
admet-423	62	43	and	and	CCONJ
admet-423	62	44	γ	γ	X
admet-423	62	45	;	;	PUNCT
admet-423	62	46	progesterone	progesterone	NOUN
admet-423	62	47	receptor	receptor	NOUN
admet-423	62	48	;	;	PUNCT
admet-423	62	49	retinoid	retinoid	X
admet-423	62	50	x	x	SYM
admet-423	62	51	receptor	receptor	NOUN
admet-423	62	52	α	α	NOUN
admet-423	62	53	;	;	PUNCT
admet-423	62	54	thyroid	thyroid	NOUN
admet-423	62	55	receptors	receptor	NOUN
admet-423	62	56	α	α	NOUN
admet-423	62	57	and	and	CCONJ
admet-423	62	58	β	β	X
admet-423	63	1	[	[	X
admet-423	63	2	20	20	NUM
admet-423	63	3	]	]	PUNCT
admet-423	63	4	.	.	PUNCT
admet-423	64	1	the	the	DET
admet-423	64	2	service	service	NOUN
admet-423	64	3	was	be	AUX
admet-423	64	4	validated	validate	VERB
admet-423	64	5	on	on	ADP
admet-423	64	6	small	small	ADJ
admet-423	64	7	drug	drug	NOUN
admet-423	64	8	-	-	PUNCT
admet-423	64	9	like	like	ADJ
admet-423	64	10	molecules	molecule	NOUN
admet-423	64	11	with	with	ADP
admet-423	64	12	molecular	molecular	ADJ
admet-423	64	13	weight	weight	NOUN
admet-423	64	14	under	under	ADP
admet-423	64	15	600	600	NUM
admet-423	64	16	.	.	PUNCT
admet-423	65	1	results	result	NOUN
admet-423	65	2	furnished	furnish	VERB
admet-423	65	3	by	by	ADP
admet-423	65	4	endocrine	endocrine	ADJ
admet-423	65	5	disruptome	disruptome	NOUN
admet-423	65	6	are	be	AUX
admet-423	65	7	dived	dive	VERB
admet-423	65	8	in	in	ADP
admet-423	65	9	4	4	NUM
admet-423	65	10	classes	class	NOUN
admet-423	65	11	based	base	VERB
admet-423	65	12	on	on	ADP
admet-423	65	13	three	three	NUM
admet-423	65	14	thresholds	threshold	NOUN
admet-423	65	15	of	of	ADP
admet-423	65	16	sensitivity	sensitivity	NOUN
admet-423	65	17	(	(	PUNCT
admet-423	65	18	se	se	X
admet-423	65	19	)	)	PUNCT
admet-423	65	20	that	that	PRON
admet-423	65	21	are	be	AUX
admet-423	65	22	set	set	VERB
admet-423	65	23	per	per	ADP
admet-423	65	24	structure	structure	NOUN
admet-423	65	25	and	and	CCONJ
admet-423	65	26	are	be	AUX
admet-423	65	27	used	use	VERB
admet-423	65	28	to	to	PART
admet-423	65	29	obtain	obtain	VERB
admet-423	65	30	the	the	DET
admet-423	65	31	docking	docking	NOUN
admet-423	65	32	scores	score	NOUN
admet-423	65	33	:	:	PUNCT
admet-423	65	34	one	one	NUM
admet-423	65	35	class	class	NOUN
admet-423	65	36	with	with	ADP
admet-423	65	37	high	high	ADJ
admet-423	65	38	probability	probability	NOUN
admet-423	65	39	of	of	ADP
admet-423	65	40	binding	bind	VERB
admet-423	65	41	(	(	PUNCT
admet-423	65	42	se	se	X
admet-423	65	43	<	<	X
admet-423	65	44	0.25	0.25	NUM
admet-423	65	45	)	)	PUNCT
admet-423	65	46	,	,	PUNCT
admet-423	65	47	two	two	NUM
admet-423	65	48	classes	class	NOUN
admet-423	65	49	with	with	ADP
admet-423	65	50	medium	medium	ADJ
admet-423	65	51	probability	probability	NOUN
admet-423	65	52	of	of	ADP
admet-423	65	53	binding	bind	VERB
admet-423	65	54	(	(	PUNCT
admet-423	65	55	0.25	0.25	NUM
admet-423	65	56	<	<	X
admet-423	65	57	se	se	X
admet-423	65	58	<	<	X
admet-423	65	59	0.50	0.50	NUM
admet-423	65	60	and	and	CCONJ
admet-423	65	61	0.50	0.50	NUM
admet-423	65	62	<	<	X
admet-423	65	63	se	se	X
admet-423	65	64	<	<	X
admet-423	65	65	0.75	0.75	NUM
admet-423	65	66	)	)	PUNCT
admet-423	65	67	and	and	CCONJ
admet-423	65	68	one	one	NUM
admet-423	65	69	class	class	NOUN
admet-423	65	70	with	with	ADP
admet-423	65	71	low	low	ADJ
admet-423	65	72	probability	probability	NOUN
admet-423	65	73	of	of	ADP
admet-423	65	74	binding	bind	VERB
admet-423	65	75	.	.	PUNCT
admet-423	66	1	(	(	PUNCT
admet-423	66	2	se	se	X
admet-423	66	3	>	>	X
admet-423	66	4	0.75	0.75	NUM
admet-423	66	5	)	)	PUNCT
admet-423	67	1	[	[	X
admet-423	67	2	20	20	NUM
admet-423	67	3	]	]	PUNCT
admet-423	67	4	.	.	PUNCT
admet-423	68	1	results	result	NOUN
admet-423	68	2	and	and	CCONJ
admet-423	68	3	discussion	discussion	NOUN
admet-423	68	4	adme	adme	NOUN
admet-423	68	5	-	-	PUNCT
admet-423	68	6	tox	tox	NOUN
admet-423	68	7	profiles	profile	NOUN
admet-423	68	8	generated	generate	VERB
admet-423	68	9	using	use	VERB
admet-423	68	10	the	the	DET
admet-423	68	11	swissadme	swissadme	NOUN
admet-423	68	12	tool	tool	NOUN
admet-423	68	13	and	and	CCONJ
admet-423	68	14	the	the	DET
admet-423	68	15	drug	drug	NOUN
admet-423	68	16	-	-	PUNCT
admet-423	68	17	like	like	ADJ
admet-423	68	18	and	and	CCONJ
admet-423	68	19	respiratory	respiratory	ADJ
admet-423	68	20	filters	filter	NOUN
admet-423	68	21	of	of	ADP
admet-423	68	22	implemented	implement	VERB
admet-423	68	23	under	under	ADP
admet-423	68	24	fafdrugs	fafdrug	NOUN
admet-423	68	25	tool	tool	NOUN
admet-423	68	26	reflect	reflect	VERB
admet-423	68	27	that	that	SCONJ
admet-423	68	28	compounds	compound	NOUN
admet-423	68	29	considered	consider	VERB
admet-423	68	30	in	in	ADP
admet-423	68	31	this	this	DET
admet-423	68	32	study	study	NOUN
admet-423	68	33	do	do	AUX
admet-423	68	34	not	not	PART
admet-423	68	35	possess	possess	VERB
admet-423	68	36	druglike	druglike	NOUN
admet-423	68	37	characteristics	characteristic	NOUN
admet-423	68	38	,	,	PUNCT
admet-423	68	39	some	some	PRON
admet-423	68	40	of	of	ADP
admet-423	68	41	their	their	PRON
admet-423	68	42	physicochemical	physicochemical	ADJ
admet-423	68	43	properties	property	NOUN
admet-423	68	44	(	(	PUNCT
admet-423	68	45	partition	partition	NOUN
admet-423	68	46	coefficient	coefficient	NOUN
admet-423	68	47	–	–	PUNCT
admet-423	68	48	log	log	VERB
admet-423	68	49	p	p	NOUN
admet-423	68	50	,	,	PUNCT
admet-423	68	51	number	number	NOUN
admet-423	68	52	of	of	ADP
admet-423	68	53	hydrogen	hydrogen	NOUN
admet-423	68	54	bonds	bond	NOUN
admet-423	68	55	donors	donor	NOUN
admet-423	68	56	hbd	hbd	NOUN
admet-423	68	57	,	,	PUNCT
admet-423	68	58	total	total	ADJ
admet-423	68	59	number	number	NOUN
admet-423	68	60	of	of	ADP
admet-423	68	61	hydrogen	hydrogen	NOUN
admet-423	68	62	bonds	bond	NOUN
admet-423	68	63	donors	donor	NOUN
admet-423	68	64	and	and	CCONJ
admet-423	68	65	acceptors	acceptor	NOUN
admet-423	68	66	–	–	PUNCT
admet-423	68	67	hbd_hba	hbd_hba	NOUN
admet-423	68	68	,	,	PUNCT
admet-423	68	69	topological	topological	ADJ
admet-423	68	70	polar	polar	ADJ
admet-423	68	71	surface	surface	NOUN
admet-423	68	72	area	area	NOUN
admet-423	68	73	tpsa	tpsa	PROPN
admet-423	68	74	)	)	PUNCT
admet-423	68	75	being	be	AUX
admet-423	68	76	outside	outside	ADP
admet-423	68	77	the	the	DET
admet-423	68	78	permitted	permit	VERB
admet-423	68	79	limits	limit	NOUN
admet-423	68	80	for	for	ADP
admet-423	68	81	drugs	drug	NOUN
admet-423	68	82	(	(	PUNCT
admet-423	68	83	figures	figure	NOUN
admet-423	68	84	1	1	NUM
admet-423	68	85	and	and	CCONJ
admet-423	68	86	2	2	NUM
admet-423	68	87	)	)	PUNCT
admet-423	68	88	,	,	PUNCT
admet-423	68	89	and	and	CCONJ
admet-423	68	90	such	such	ADJ
admet-423	68	91	as	as	ADP
admet-423	68	92	violating	violate	VERB
admet-423	68	93	many	many	ADJ
admet-423	68	94	rules	rule	NOUN
admet-423	68	95	(	(	PUNCT
admet-423	68	96	table	table	NOUN
admet-423	68	97	2	2	NUM
admet-423	68	98	)	)	PUNCT
admet-423	68	99	.	.	PUNCT
admet-423	69	1	figures	figure	NOUN
admet-423	69	2	1a	1a	PROPN
admet-423	69	3	and	and	CCONJ
admet-423	69	4	1b	1b	NUM
admet-423	69	5	illustrate	illustrate	VERB
admet-423	69	6	the	the	DET
admet-423	69	7	use	use	NOUN
admet-423	69	8	of	of	ADP
admet-423	69	9	fafdrugs	fafdrug	NOUN
admet-423	69	10	tool	tool	NOUN
admet-423	69	11	to	to	PART
admet-423	69	12	obtain	obtain	VERB
admet-423	69	13	the	the	DET
admet-423	69	14	positioning	positioning	NOUN
admet-423	69	15	of	of	ADP
admet-423	69	16	the	the	DET
admet-423	69	17	physicochemical	physicochemical	ADJ
admet-423	69	18	properties	property	NOUN
admet-423	69	19	of	of	ADP
admet-423	69	20	n	n	NOUN
admet-423	69	21	-	-	PUNCT
admet-423	69	22	carboxymethyl	carboxymethyl	NOUN
admet-423	69	23	chitosan	chitosan	NOUN
admet-423	69	24	(	(	PUNCT
admet-423	69	25	cmc	cmc	PROPN
admet-423	69	26	)	)	PUNCT
admet-423	69	27	(	(	PUNCT
admet-423	69	28	a	a	NOUN
admet-423	69	29	)	)	PUNCT
admet-423	69	30	and	and	CCONJ
admet-423	69	31	n	n	CCONJ
admet-423	69	32	,	,	PUNCT
admet-423	69	33	n	n	CCONJ
admet-423	69	34	,	,	PUNCT
admet-423	69	35	n	n	CCONJ
admet-423	69	36	-	-	PUNCT
admet-423	69	37	trimethyl	trimethyl	NOUN
admet-423	69	38	chitosan	chitosan	NOUN
admet-423	69	39	(	(	PUNCT
admet-423	69	40	tmc	tmc	PROPN
admet-423	69	41	)	)	PUNCT
admet-423	69	42	(	(	PUNCT
admet-423	69	43	b	b	NOUN
admet-423	69	44	)	)	PUNCT
admet-423	69	45	respectively	respectively	ADV
admet-423	69	46	by	by	ADP
admet-423	69	47	compassion	compassion	NOUN
admet-423	69	48	to	to	ADP
admet-423	69	49	the	the	DET
admet-423	69	50	drug	drug	NOUN
admet-423	69	51	-	-	PUNCT
admet-423	69	52	like	like	ADJ
admet-423	69	53	properties	property	NOUN
admet-423	69	54	.	.	PUNCT
admet-423	70	1	figures	figure	NOUN
admet-423	70	2	2a	2a	NUM
admet-423	70	3	and	and	CCONJ
admet-423	70	4	2b	2b	NOUN
admet-423	70	5	show	show	VERB
admet-423	70	6	the	the	DET
admet-423	70	7	positioning	positioning	NOUN
admet-423	70	8	of	of	ADP
admet-423	70	9	the	the	DET
admet-423	70	10	physicochemical	physicochemical	ADJ
admet-423	70	11	properties	property	NOUN
admet-423	70	12	of	of	ADP
admet-423	70	13	cmc	cmc	NOUN
admet-423	70	14	(	(	PUNCT
admet-423	70	15	a	a	NOUN
admet-423	70	16	)	)	PUNCT
admet-423	70	17	and	and	CCONJ
admet-423	70	18	tmc	tmc	PROPN
admet-423	70	19	(	(	PUNCT
admet-423	70	20	b	b	NOUN
admet-423	70	21	)	)	PUNCT
admet-423	70	22	respectively	respectively	ADV
admet-423	70	23	when	when	SCONJ
admet-423	70	24	the	the	DET
admet-423	70	25	respiratory	respiratory	ADJ
admet-423	70	26	filter	filter	NOUN
admet-423	70	27	is	be	AUX
admet-423	70	28	applied	apply	VERB
admet-423	70	29	under	under	ADP
admet-423	70	30	fafdrugs	fafdrug	NOUN
admet-423	70	31	tool	tool	NOUN
admet-423	70	32	.	.	PUNCT
admet-423	71	1	figure	figure	NOUN
admet-423	71	2	1	1	NUM
admet-423	71	3	.	.	PUNCT
admet-423	71	4	radar	radar	NOUN
admet-423	71	5	pictures	picture	NOUN
admet-423	71	6	of	of	ADP
admet-423	71	7	the	the	DET
admet-423	71	8	positioning	positioning	NOUN
admet-423	71	9	of	of	ADP
admet-423	71	10	the	the	DET
admet-423	71	11	physicochemical	physicochemical	ADJ
admet-423	71	12	properties	property	NOUN
admet-423	71	13	of	of	ADP
admet-423	71	14	investigated	investigate	VERB
admet-423	71	15	compounds	compound	NOUN
admet-423	71	16	(	(	PUNCT
admet-423	71	17	dark	dark	ADJ
admet-423	71	18	blue	blue	ADJ
admet-423	71	19	line	line	NOUN
admet-423	71	20	)	)	PUNCT
admet-423	71	21	by	by	ADP
admet-423	71	22	comparison	comparison	NOUN
admet-423	71	23	to	to	ADP
admet-423	71	24	the	the	DET
admet-423	71	25	properties	property	NOUN
admet-423	71	26	corresponding	correspond	VERB
admet-423	71	27	to	to	ADP
admet-423	71	28	drug	drug	NOUN
admet-423	71	29	-	-	PUNCT
admet-423	71	30	like	like	ADJ
admet-423	71	31	molecules	molecule	NOUN
admet-423	71	32	(	(	PUNCT
admet-423	71	33	light	light	ADJ
admet-423	71	34	blue	blue	ADJ
admet-423	71	35	region	region	NOUN
admet-423	71	36	)	)	PUNCT
admet-423	72	1	(	(	PUNCT
admet-423	72	2	a	a	X
admet-423	72	3	)	)	PUNCT
admet-423	72	4	ncarboxymethyl	ncarboxymethyl	ADJ
admet-423	72	5	chitosan	chitosan	NOUN
admet-423	72	6	,	,	PUNCT
admet-423	72	7	(	(	PUNCT
admet-423	72	8	b	b	NOUN
admet-423	72	9	)	)	PUNCT
admet-423	72	10	n	n	CCONJ
admet-423	72	11	,	,	PUNCT
admet-423	72	12	n	n	CCONJ
admet-423	72	13	,	,	PUNCT
admet-423	72	14	n	n	CCONJ
admet-423	72	15	-	-	PUNCT
admet-423	72	16	trimethyl	trimethyl	NOUN
admet-423	72	17	-	-	PUNCT
admet-423	72	18	chitosan	chitosan	NOUN
admet-423	72	19	.	.	PUNCT
admet-423	73	1	(	(	PUNCT
admet-423	73	2	a	a	X
admet-423	73	3	)	)	PUNCT
admet-423	73	4	(	(	PUNCT
admet-423	73	5	b	b	NOUN
admet-423	73	6	)	)	PUNCT
admet-423	73	7	isvoran	isvoran	ADJ
admet-423	73	8	,	,	PUNCT
admet-423	73	9	ciorsac	ciorsac	NOUN
admet-423	73	10	,	,	PUNCT
admet-423	73	11	ostafe	ostafe	NOUN
admet-423	73	12	admet	admet	PROPN
admet-423	73	13	&	&	CCONJ
admet-423	73	14	dmpk	dmpk	PROPN
admet-423	73	15	5(3	5(3	NUM
admet-423	73	16	)	)	PUNCT
admet-423	73	17	(	(	PUNCT
admet-423	73	18	2017	2017	NUM
admet-423	73	19	)	)	PUNCT
admet-423	73	20	192	192	NUM
admet-423	73	21	-	-	SYM
admet-423	73	22	200	200	NUM
admet-423	73	23	196	196	NUM
admet-423	73	24	figure	figure	NOUN
admet-423	73	25	2	2	NUM
admet-423	73	26	.	.	PUNCT
admet-423	73	27	radar	radar	NOUN
admet-423	73	28	pictures	picture	NOUN
admet-423	73	29	of	of	ADP
admet-423	73	30	the	the	DET
admet-423	73	31	positioning	positioning	NOUN
admet-423	73	32	of	of	ADP
admet-423	73	33	the	the	DET
admet-423	73	34	physicochemical	physicochemical	ADJ
admet-423	73	35	properties	property	NOUN
admet-423	73	36	of	of	ADP
admet-423	73	37	investigated	investigate	VERB
admet-423	73	38	compounds	compound	NOUN
admet-423	73	39	(	(	PUNCT
admet-423	73	40	dark	dark	ADJ
admet-423	73	41	blue	blue	ADJ
admet-423	73	42	line	line	NOUN
admet-423	73	43	)	)	PUNCT
admet-423	73	44	by	by	ADP
admet-423	73	45	comparison	comparison	NOUN
admet-423	73	46	to	to	ADP
admet-423	73	47	the	the	DET
admet-423	73	48	properties	property	NOUN
admet-423	73	49	corresponding	correspond	VERB
admet-423	73	50	to	to	ADP
admet-423	73	51	molecules	molecule	NOUN
admet-423	73	52	that	that	PRON
admet-423	73	53	can	can	AUX
admet-423	73	54	be	be	AUX
admet-423	73	55	used	use	VERB
admet-423	73	56	as	as	ADP
admet-423	73	57	respiratory	respiratory	ADJ
admet-423	73	58	drugs	drug	NOUN
admet-423	73	59	(	(	PUNCT
admet-423	73	60	light	light	ADJ
admet-423	73	61	blue	blue	ADJ
admet-423	73	62	region	region	NOUN
admet-423	73	63	)	)	PUNCT
admet-423	73	64	(	(	PUNCT
admet-423	73	65	a	a	X
admet-423	73	66	)	)	PUNCT
admet-423	73	67	n	n	CCONJ
admet-423	73	68	-	-	PUNCT
admet-423	73	69	carboxymethyl	carboxymethyl	NOUN
admet-423	73	70	chitosan	chitosan	NOUN
admet-423	73	71	,	,	PUNCT
admet-423	73	72	(	(	PUNCT
admet-423	73	73	b	b	NOUN
admet-423	73	74	)	)	PUNCT
admet-423	73	75	n	n	CCONJ
admet-423	73	76	,	,	PUNCT
admet-423	73	77	n	n	CCONJ
admet-423	73	78	,	,	PUNCT
admet-423	73	79	n	n	CCONJ
admet-423	73	80	-	-	PUNCT
admet-423	73	81	trimethyl	trimethyl	NOUN
admet-423	73	82	-	-	PUNCT
admet-423	73	83	chitosan	chitosan	NOUN
admet-423	73	84	.	.	PUNCT
admet-423	74	1	table	table	NOUN
admet-423	74	2	2	2	NUM
admet-423	74	3	.	.	X
admet-423	74	4	druglikeness	druglikeness	NOUN
admet-423	74	5	of	of	ADP
admet-423	74	6	the	the	DET
admet-423	74	7	wscd	wscd	NOUN
admet-423	74	8	considered	consider	VERB
admet-423	74	9	in	in	ADP
admet-423	74	10	this	this	DET
admet-423	74	11	study	study	NOUN
admet-423	74	12	compound	compound	NOUN
admet-423	74	13	number	number	NOUN
admet-423	74	14	of	of	ADP
admet-423	74	15	violations	violation	NOUN
admet-423	74	16	lilly	lilly	PROPN
admet-423	74	17	medchem	medchem	PROPN
admet-423	74	18	rules	rule	VERB
admet-423	74	19	bioavailability	bioavailability	NOUN
admet-423	74	20	score	score	NOUN
admet-423	74	21	lipinski	lipinski	PROPN
admet-423	74	22	ghose	ghose	PROPN
admet-423	74	23	(	(	PUNCT
admet-423	74	24	bayer	bayer	PROPN
admet-423	74	25	)	)	PUNCT
admet-423	74	26	veber	veber	PROPN
admet-423	74	27	egan	egan	PROPN
admet-423	74	28	muege	muege	PROPN
admet-423	74	29	deacetylated	deacetylate	VERB
admet-423	74	30	chitosan	chitosan	NOUN
admet-423	74	31	(	(	PUNCT
admet-423	74	32	2	2	NUM
admet-423	74	33	units	unit	NOUN
admet-423	74	34	)	)	PUNCT
admet-423	74	35	2	2	NUM
admet-423	74	36	1	1	NUM
admet-423	74	37	1	1	NUM
admet-423	74	38	1	1	NUM
admet-423	74	39	4	4	NUM
admet-423	74	40	pass	pass	NOUN
admet-423	74	41	0.17	0.17	NUM
admet-423	74	42	partially	partially	ADV
admet-423	74	43	deacetylated	deacetylate	VERB
admet-423	74	44	chitosan	chitosan	NOUN
admet-423	74	45	(	(	PUNCT
admet-423	74	46	2	2	NUM
admet-423	74	47	units	unit	NOUN
admet-423	74	48	)	)	PUNCT
admet-423	74	49	2	2	NUM
admet-423	74	50	3	3	NUM
admet-423	74	51	1	1	NUM
admet-423	74	52	1	1	NUM
admet-423	74	53	4	4	NUM
admet-423	74	54	pass	pass	VERB
admet-423	74	55	0.17	0.17	NUM
admet-423	74	56	n	n	CCONJ
admet-423	74	57	-	-	PUNCT
admet-423	74	58	carboxymethyl	carboxymethyl	NOUN
admet-423	74	59	chitosan	chitosan	NOUN
admet-423	74	60	1	1	NUM
admet-423	74	61	1	1	NUM
admet-423	74	62	0	0	NUM
admet-423	74	63	1	1	NUM
admet-423	74	64	2	2	NUM
admet-423	74	65	pass	pass	VERB
admet-423	74	66	0.55	0.55	NUM
admet-423	74	67	o	o	NOUN
admet-423	74	68	-	-	NOUN
admet-423	74	69	carboxymethyl	carboxymethyl	NOUN
admet-423	74	70	chitosan	chitosan	NOUN
admet-423	74	71	0	0	NUM
admet-423	74	72	1	1	NUM
admet-423	74	73	1	1	NUM
admet-423	74	74	1	1	NUM
admet-423	74	75	1	1	NUM
admet-423	74	76	pass	pass	VERB
admet-423	74	77	0.55	0.55	NUM
admet-423	74	78	n	n	CCONJ
admet-423	74	79	,	,	PUNCT
admet-423	74	80	n	n	CCONJ
admet-423	74	81	-	-	PUNCT
admet-423	74	82	carboxymethyl	carboxymethyl	NOUN
admet-423	74	83	chitosan	chitosan	NOUN
admet-423	74	84	1	1	NUM
admet-423	74	85	1	1	NUM
admet-423	74	86	1	1	NUM
admet-423	74	87	1	1	NUM
admet-423	74	88	3	3	NUM
admet-423	74	89	pass	pass	VERB
admet-423	74	90	0.11	0.11	NUM
admet-423	74	91	n	n	NOUN
admet-423	74	92	,	,	PUNCT
admet-423	74	93	o	o	NOUN
admet-423	74	94	-	-	NOUN
admet-423	74	95	carboxymethyl	carboxymethyl	NOUN
admet-423	74	96	chitosan	chitosan	NOUN
admet-423	74	97	1	1	NUM
admet-423	74	98	1	1	NUM
admet-423	74	99	1	1	NUM
admet-423	74	100	1	1	NUM
admet-423	74	101	3	3	NUM
admet-423	74	102	pass	pass	VERB
admet-423	74	103	0.11	0.11	NUM
admet-423	74	104	n	n	CCONJ
admet-423	74	105	,	,	PUNCT
admet-423	74	106	n	n	CCONJ
admet-423	74	107	,	,	PUNCT
admet-423	74	108	o	o	NOUN
admet-423	74	109	-	-	NOUN
admet-423	74	110	carboxymethyl	carboxymethyl	NOUN
admet-423	74	111	chitosan	chitosan	NOUN
admet-423	74	112	2	2	NUM
admet-423	74	113	1	1	NUM
admet-423	74	114	1	1	NUM
admet-423	74	115	1	1	NUM
admet-423	74	116	4	4	NUM
admet-423	74	117	do	do	AUX
admet-423	74	118	not	not	PART
admet-423	74	119	pass	pass	VERB
admet-423	74	120	0.11	0.11	NUM
admet-423	74	121	n	n	CCONJ
admet-423	74	122	,	,	PUNCT
admet-423	74	123	n	n	CCONJ
admet-423	74	124	,	,	PUNCT
admet-423	74	125	n	n	CCONJ
admet-423	74	126	-	-	PUNCT
admet-423	74	127	trimethyl	trimethyl	NOUN
admet-423	74	128	-	-	PUNCT
admet-423	74	129	chitosan	chitosan	NOUN
admet-423	74	130	1	1	NUM
admet-423	74	131	1	1	NUM
admet-423	74	132	1	1	NUM
admet-423	74	133	1	1	NUM
admet-423	74	134	3	3	NUM
admet-423	74	135	pass	pass	VERB
admet-423	74	136	0.55	0.55	NUM
admet-423	74	137	chitosan	chitosan	NOUN
admet-423	74	138	-	-	PUNCT
admet-423	74	139	lactate	lactate	NOUN
admet-423	74	140	1	1	NUM
admet-423	74	141	1	1	NUM
admet-423	74	142	0	0	NUM
admet-423	74	143	1	1	NUM
admet-423	74	144	1	1	NUM
admet-423	74	145	pass	pass	NOUN
admet-423	74	146	0.55	0.55	NUM
admet-423	74	147	hydroxyethyl	hydroxyethyl	NOUN
admet-423	74	148	chitosan	chitosan	ADJ
admet-423	74	149	2	2	NUM
admet-423	74	150	1	1	NUM
admet-423	74	151	2	2	NUM
admet-423	74	152	1	1	NUM
admet-423	74	153	4	4	NUM
admet-423	74	154	pass	pass	NOUN
admet-423	74	155	0.17	0.17	NUM
admet-423	74	156	hydroxypropyl	hydroxypropyl	NOUN
admet-423	74	157	chitosan	chitosan	ADJ
admet-423	74	158	2	2	NUM
admet-423	74	159	3	3	NUM
admet-423	74	160	2	2	NUM
admet-423	74	161	1	1	NUM
admet-423	74	162	4	4	NUM
admet-423	74	163	pass	pass	VERB
admet-423	74	164	0.17	0.17	NUM
admet-423	74	165	dihydroxypropyl	dihydroxypropyl	NOUN
admet-423	74	166	chitosan	chitosan	NOUN
admet-423	74	167	2	2	NUM
admet-423	74	168	3	3	NUM
admet-423	74	169	2	2	NUM
admet-423	74	170	1	1	NUM
admet-423	74	171	4	4	NUM
admet-423	74	172	pass	pass	VERB
admet-423	74	173	0.17	0.17	NUM
admet-423	74	174	n-(2	n-(2	PROPN
admet-423	74	175	-	-	PUNCT
admet-423	74	176	hydroxy)propyl-3trimethylammonium	hydroxy)propyl-3trimethylammonium	NOUN
admet-423	74	177	chitosan	chitosan	NOUN
admet-423	74	178	2	2	NUM
admet-423	74	179	3	3	NUM
admet-423	74	180	2	2	NUM
admet-423	74	181	1	1	NUM
admet-423	74	182	4	4	NUM
admet-423	74	183	do	do	AUX
admet-423	74	184	not	not	PART
admet-423	74	185	pass	pass	VERB
admet-423	74	186	0.17	0.17	NUM
admet-423	74	187	o-(2	o-(2	NOUN
admet-423	74	188	-	-	PUNCT
admet-423	74	189	hydroxy)propyl-3trimethylammonium	hydroxy)propyl-3trimethylammonium	NOUN
admet-423	74	190	chitosan	chitosan	NOUN
admet-423	74	191	2	2	NUM
admet-423	74	192	3	3	NUM
admet-423	74	193	2	2	NUM
admet-423	74	194	1	1	NUM
admet-423	74	195	4	4	NUM
admet-423	74	196	do	do	AUX
admet-423	74	197	not	not	PART
admet-423	74	198	pass	pass	VERB
admet-423	74	199	0.17	0.17	NUM
admet-423	74	200	n-(4	n-(4	ADV
admet-423	74	201	-	-	PUNCT
admet-423	74	202	carboxybutyroyl	carboxybutyroyl	NOUN
admet-423	74	203	)	)	PUNCT
admet-423	75	1	chitosan	chitosan	NOUN
admet-423	75	2	2	2	NUM
admet-423	75	3	1	1	NUM
admet-423	75	4	1	1	NUM
admet-423	75	5	1	1	NUM
admet-423	75	6	4	4	NUM
admet-423	75	7	pass	pass	VERB
admet-423	75	8	0.17	0.17	NUM
admet-423	75	9	n	n	CCONJ
admet-423	75	10	-	-	PUNCT
admet-423	75	11	trimethyl	trimethyl	NOUN
admet-423	75	12	chitosan	chitosan	NOUN
admet-423	75	13	2	2	NUM
admet-423	75	14	1	1	NUM
admet-423	75	15	1	1	NUM
admet-423	75	16	1	1	NUM
admet-423	75	17	3	3	NUM
admet-423	75	18	do	do	AUX
admet-423	75	19	not	not	PART
admet-423	75	20	pass	pass	VERB
admet-423	75	21	0.17	0.17	NUM
admet-423	75	22	with	with	ADP
admet-423	75	23	the	the	DET
admet-423	75	24	exception	exception	NOUN
admet-423	75	25	of	of	ADP
admet-423	75	26	n	n	CCONJ
admet-423	75	27	-	-	PUNCT
admet-423	75	28	carboxymethyl	carboxymethyl	NOUN
admet-423	75	29	chitosan	chitosan	NOUN
admet-423	75	30	,	,	PUNCT
admet-423	75	31	o	o	NOUN
admet-423	75	32	-	-	NOUN
admet-423	75	33	carboxymethyl	carboxymethyl	NOUN
admet-423	75	34	chitosan	chitosan	NOUN
admet-423	75	35	and	and	CCONJ
admet-423	75	36	n	n	CCONJ
admet-423	75	37	,	,	PUNCT
admet-423	75	38	n	n	CCONJ
admet-423	75	39	,	,	PUNCT
admet-423	75	40	n	n	CCONJ
admet-423	75	41	-	-	PUNCT
admet-423	75	42	trimethylchitosan	trimethylchitosan	NOUN
admet-423	75	43	,	,	PUNCT
admet-423	75	44	chitosan	chitosan	NOUN
admet-423	75	45	and	and	CCONJ
admet-423	75	46	the	the	DET
admet-423	75	47	other	other	ADJ
admet-423	75	48	wsdc	wsdc	NOUN
admet-423	75	49	reveal	reveal	VERB
admet-423	75	50	a	a	DET
admet-423	75	51	low	low	ADJ
admet-423	75	52	oral	oral	ADJ
admet-423	75	53	bioavailability	bioavailability	NOUN
admet-423	75	54	.	.	PUNCT
admet-423	76	1	from	from	ADP
admet-423	76	2	the	the	DET
admet-423	76	3	point	point	NOUN
admet-423	76	4	of	of	ADP
admet-423	76	5	view	view	NOUN
admet-423	76	6	of	of	ADP
admet-423	76	7	safety	safety	NOUN
admet-423	76	8	,	,	PUNCT
admet-423	76	9	fafdrugs	fafdrug	NOUN
admet-423	76	10	tool	tool	NOUN
admet-423	76	11	exposes	expose	VERB
admet-423	76	12	that	that	SCONJ
admet-423	76	13	all	all	DET
admet-423	76	14	these	these	DET
admet-423	76	15	compounds	compound	NOUN
admet-423	76	16	reflect	reflect	VERB
admet-423	76	17	no	no	DET
admet-423	76	18	toxicity	toxicity	NOUN
admet-423	76	19	,	,	PUNCT
admet-423	76	20	but	but	CCONJ
admet-423	76	21	some	some	PRON
admet-423	76	22	of	of	ADP
admet-423	76	23	them	they	PRON
admet-423	76	24	are	be	AUX
admet-423	76	25	able	able	ADJ
admet-423	76	26	to	to	PART
admet-423	76	27	induce	induce	VERB
admet-423	76	28	phospholipidosis	phospholipidosis	NOUN
admet-423	76	29	.	.	PUNCT
admet-423	77	1	it	it	PRON
admet-423	77	2	is	be	AUX
admet-423	77	3	not	not	PART
admet-423	77	4	an	an	DET
admet-423	77	5	unexpected	unexpected	ADJ
admet-423	77	6	result	result	NOUN
admet-423	77	7	,	,	PUNCT
admet-423	77	8	as	as	SCONJ
admet-423	77	9	it	it	PRON
admet-423	77	10	is	be	AUX
admet-423	77	11	generally	generally	ADV
admet-423	77	12	recognized	recognize	VERB
admet-423	77	13	that	that	SCONJ
admet-423	77	14	phospholipidosis	phospholipidosis	NOUN
admet-423	77	15	is	be	AUX
admet-423	77	16	a	a	DET
admet-423	77	17	response	response	NOUN
admet-423	77	18	to	to	ADP
admet-423	77	19	cells	cell	NOUN
admet-423	77	20	exposed	expose	VERB
admet-423	77	21	to	to	ADP
admet-423	77	22	cationic	cationic	ADJ
admet-423	77	23	amphiphilic	amphiphilic	ADJ
admet-423	77	24	substances	substance	NOUN
admet-423	77	25	[	[	X
admet-423	77	26	27	27	NUM
admet-423	77	27	]	]	PUNCT
admet-423	77	28	.	.	PUNCT
admet-423	78	1	pharmacokinetics	pharmacokinetic	NOUN
admet-423	78	2	of	of	ADP
admet-423	78	3	investigated	investigate	VERB
admet-423	78	4	compounds	compound	NOUN
admet-423	78	5	has	have	AUX
admet-423	78	6	been	be	AUX
admet-423	78	7	obtained	obtain	VERB
admet-423	78	8	using	use	VERB
admet-423	78	9	swissadme	swissadme	NOUN
admet-423	78	10	tool	tool	NOUN
admet-423	78	11	and	and	CCONJ
admet-423	78	12	is	be	AUX
admet-423	78	13	revealed	reveal	VERB
admet-423	78	14	in	in	ADP
admet-423	78	15	table	table	NOUN
admet-423	78	16	3	3	NUM
admet-423	78	17	.	.	PUNCT
admet-423	79	1	the	the	DET
admet-423	79	2	results	result	NOUN
admet-423	79	3	presented	present	VERB
admet-423	79	4	in	in	ADP
admet-423	79	5	table	table	NOUN
admet-423	79	6	3	3	NUM
admet-423	79	7	indicate	indicate	VERB
admet-423	79	8	that	that	SCONJ
admet-423	79	9	all	all	DET
admet-423	79	10	investigated	investigate	VERB
admet-423	79	11	compounds	compound	NOUN
admet-423	79	12	present	present	VERB
admet-423	79	13	a	a	DET
admet-423	79	14	low	low	ADJ
admet-423	79	15	gastrointestinal	gastrointestinal	ADJ
admet-423	79	16	absorption	absorption	NOUN
admet-423	79	17	,	,	PUNCT
admet-423	79	18	low	low	ADJ
admet-423	79	19	skin	skin	NOUN
admet-423	79	20	permeation	permeation	NOUN
admet-423	79	21	and	and	CCONJ
admet-423	79	22	they	they	PRON
admet-423	79	23	are	be	AUX
admet-423	79	24	not	not	PART
admet-423	79	25	able	able	ADJ
admet-423	79	26	to	to	PART
admet-423	79	27	inhibit	inhibit	VERB
admet-423	79	28	any	any	PRON
admet-423	79	29	of	of	ADP
admet-423	79	30	the	the	DET
admet-423	79	31	cytochromes	cytochrome	NOUN
admet-423	79	32	p450	p450	PROPN
admet-423	79	33	(	(	PUNCT
admet-423	79	34	cyp	cyp	ADJ
admet-423	79	35	)	)	PUNCT
admet-423	79	36	involved	involve	VERB
admet-423	79	37	in	in	ADP
admet-423	79	38	metabolism	metabolism	NOUN
admet-423	79	39	of	of	ADP
admet-423	79	40	xenobiotics	xenobiotics	PROPN
admet-423	79	41	.	.	PUNCT
admet-423	80	1	these	these	DET
admet-423	80	2	compounds	compound	NOUN
admet-423	80	3	are	be	AUX
admet-423	80	4	predicted	predict	VERB
admet-423	80	5	to	to	PART
admet-423	80	6	be	be	AUX
admet-423	80	7	substrates	substrate	NOUN
admet-423	80	8	for	for	ADP
admet-423	80	9	(	(	PUNCT
admet-423	80	10	a	a	NOUN
admet-423	80	11	)	)	PUNCT
admet-423	80	12	(	(	PUNCT
admet-423	80	13	b	b	X
admet-423	80	14	)	)	PUNCT
admet-423	80	15	admet	admet	PROPN
admet-423	80	16	&	&	CCONJ
admet-423	80	17	dmpk	dmpk	PROPN
admet-423	80	18	5(3	5(3	NUM
admet-423	80	19	)	)	PUNCT
admet-423	80	20	(	(	PUNCT
admet-423	80	21	2017	2017	NUM
admet-423	80	22	)	)	PUNCT
admet-423	80	23	192	192	NUM
admet-423	80	24	-	-	SYM
admet-423	80	25	200	200	NUM
admet-423	80	26	admet	admet	NOUN
admet-423	80	27	of	of	ADP
admet-423	80	28	chitosan	chitosan	NOUN
admet-423	80	29	derivatives	derivative	NOUN
admet-423	80	30	doi	doi	NOUN
admet-423	80	31	:	:	PUNCT
admet-423	80	32	10.5599	10.5599	NUM
admet-423	80	33	/	/	SYM
admet-423	80	34	admet.5.3.423	admet.5.3.423	PRON
admet-423	80	35	197	197	NUM
admet-423	80	36	p	p	NOUN
admet-423	80	37	-	-	PUNCT
admet-423	80	38	gp	gp	NOUN
admet-423	80	39	,	,	PUNCT
admet-423	80	40	another	another	DET
admet-423	80	41	pharmacokinetics	pharmacokinetic	NOUN
admet-423	80	42	-	-	PUNCT
admet-423	80	43	relevant	relevant	ADJ
admet-423	80	44	protein	protein	NOUN
admet-423	80	45	,	,	PUNCT
admet-423	80	46	emphasizing	emphasize	VERB
admet-423	80	47	their	their	PRON
admet-423	80	48	active	active	ADJ
admet-423	80	49	efflux	efflux	NOUN
admet-423	80	50	through	through	ADP
admet-423	80	51	biological	biological	ADJ
admet-423	80	52	membranes	membrane	NOUN
admet-423	80	53	.	.	PUNCT
admet-423	81	1	table	table	NOUN
admet-423	81	2	3	3	NUM
admet-423	81	3	.	.	PUNCT
admet-423	82	1	pharmacokinetics	pharmacokinetic	NOUN
admet-423	82	2	of	of	ADP
admet-423	82	3	water	water	NOUN
admet-423	82	4	soluble	soluble	ADJ
admet-423	82	5	chitosan	chitosan	NOUN
admet-423	82	6	derivatives	derivative	NOUN
admet-423	82	7	:	:	PUNCT
admet-423	82	8	gigastrointestinal	gigastrointestinal	ADJ
admet-423	82	9	absorption	absorption	NOUN
admet-423	82	10	,	,	PUNCT
admet-423	82	11	bbb	bbb	PROPN
admet-423	82	12	–	–	PUNCT
admet-423	82	13	blood	blood	NOUN
admet-423	82	14	brain	brain	NOUN
admet-423	82	15	barrier	barrier	NOUN
admet-423	82	16	penetration	penetration	NOUN
admet-423	82	17	,	,	PUNCT
admet-423	82	18	p	p	NOUN
admet-423	82	19	-	-	PUNCT
admet-423	82	20	gp	gp	NOUN
admet-423	82	21	–	–	PUNCT
admet-423	82	22	substrate	substrate	NOUN
admet-423	82	23	of	of	ADP
admet-423	82	24	the	the	DET
admet-423	82	25	p	p	NOUN
admet-423	82	26	-	-	PUNCT
admet-423	82	27	gp	gp	NOUN
admet-423	82	28	protein	protein	NOUN
admet-423	82	29	,	,	PUNCT
admet-423	82	30	cypcytochrome	cypcytochrome	ADJ
admet-423	82	31	p450	p450	NUM
admet-423	82	32	,	,	PUNCT
admet-423	82	33	log	log	PROPN
admet-423	82	34	kp	kp	PROPN
admet-423	82	35	–	–	PUNCT
admet-423	82	36	skin	skin	NOUN
admet-423	82	37	permeation	permeation	NOUN
admet-423	82	38	coefficient	coefficient	NOUN
admet-423	82	39	compound	compound	PROPN
admet-423	82	40	gi	gi	PROPN
admet-423	82	41	bbb	bbb	PROPN
admet-423	82	42	p	p	PROPN
admet-423	82	43	-	-	PUNCT
admet-423	82	44	gp	gp	NOUN
admet-423	82	45	cyp1a2	cyp1a2	NOUN
admet-423	82	46	cyp2d6	cyp2d6	PROPN
admet-423	82	47	cyp2c9	cyp2c9	PROPN
admet-423	82	48	cyp2c19	cyp2c19	PROPN
admet-423	82	49	cyp3a	cyp3a	PROPN
admet-423	82	50	4	4	NUM
admet-423	82	51	log	log	NOUN
admet-423	82	52	kp	kp	PROPN
admet-423	82	53	(	(	PUNCT
admet-423	82	54	cm	cm	NOUN
admet-423	82	55	/	/	SYM
admet-423	82	56	s	s	PART
admet-423	82	57	)	)	PUNCT
admet-423	82	58	deacetylated	deacetylate	VERB
admet-423	82	59	chitosan	chitosan	NOUN
admet-423	82	60	low	low	NOUN
admet-423	83	1	no	no	INTJ
admet-423	83	2	yes	yes	INTJ
admet-423	84	1	no	no	INTJ
admet-423	84	2	no	no	INTJ
admet-423	85	1	no	no	INTJ
admet-423	85	2	no	no	INTJ
admet-423	86	1	no	no	INTJ
admet-423	86	2	-12.10	-12.10	PROPN
admet-423	86	3	partially	partially	ADV
admet-423	86	4	deacetylated	deacetylate	VERB
admet-423	86	5	chitosan	chitosan	NOUN
admet-423	86	6	low	low	NOUN
admet-423	87	1	no	no	INTJ
admet-423	87	2	yes	yes	INTJ
admet-423	88	1	no	no	INTJ
admet-423	88	2	no	no	INTJ
admet-423	89	1	no	no	INTJ
admet-423	89	2	no	no	INTJ
admet-423	90	1	no	no	INTJ
admet-423	90	2	-12.18	-12.18	X
admet-423	90	3	o	o	NOUN
admet-423	90	4	-	-	NOUN
admet-423	90	5	carboxymethyl	carboxymethyl	NOUN
admet-423	90	6	chitosan	chitosan	NOUN
admet-423	90	7	low	low	NOUN
admet-423	91	1	no	no	INTJ
admet-423	91	2	yes	yes	INTJ
admet-423	92	1	no	no	INTJ
admet-423	92	2	no	no	INTJ
admet-423	93	1	no	no	INTJ
admet-423	93	2	no	no	INTJ
admet-423	94	1	no	no	INTJ
admet-423	94	2	-11.69	-11.69	NOUN
admet-423	94	3	n	n	CCONJ
admet-423	94	4	,	,	PUNCT
admet-423	94	5	n	n	CCONJ
admet-423	94	6	-	-	PUNCT
admet-423	94	7	carboxymethyl	carboxymethyl	NOUN
admet-423	94	8	chitosan	chitosan	ADJ
admet-423	94	9	low	low	NOUN
admet-423	95	1	no	no	INTJ
admet-423	95	2	yes	yes	INTJ
admet-423	96	1	no	no	INTJ
admet-423	96	2	no	no	INTJ
admet-423	97	1	no	no	INTJ
admet-423	97	2	no	no	INTJ
admet-423	97	3	no	no	INTJ
admet-423	97	4	-12.08	-12.08	PROPN
admet-423	97	5	n	n	CCONJ
admet-423	97	6	,	,	PUNCT
admet-423	97	7	o	o	NOUN
admet-423	97	8	-	-	NOUN
admet-423	97	9	carboxymethyl	carboxymethyl	NOUN
admet-423	97	10	chitosan	chitosan	NOUN
admet-423	97	11	low	low	NOUN
admet-423	98	1	no	no	INTJ
admet-423	98	2	yes	yes	INTJ
admet-423	99	1	no	no	INTJ
admet-423	99	2	no	no	INTJ
admet-423	100	1	no	no	INTJ
admet-423	100	2	no	no	INTJ
admet-423	100	3	no	no	INTJ
admet-423	100	4	-11.96	-11.96	NOUN
admet-423	100	5	n	n	CCONJ
admet-423	100	6	,	,	PUNCT
admet-423	100	7	n	n	CCONJ
admet-423	100	8	,	,	PUNCT
admet-423	100	9	o	o	NOUN
admet-423	100	10	-	-	NOUN
admet-423	100	11	carboxymethyl	carboxymethyl	NOUN
admet-423	100	12	chitosan	chitosan	NOUN
admet-423	100	13	low	low	NOUN
admet-423	101	1	no	no	INTJ
admet-423	101	2	yes	yes	INTJ
admet-423	102	1	no	no	INTJ
admet-423	102	2	no	no	INTJ
admet-423	103	1	no	no	INTJ
admet-423	103	2	no	no	INTJ
admet-423	103	3	no	no	INTJ
admet-423	103	4	-12.27	-12.27	PUNCT
admet-423	103	5	n	n	CCONJ
admet-423	103	6	-	-	PUNCT
admet-423	103	7	carboxymethyl	carboxymethyl	NOUN
admet-423	103	8	chitosan	chitosan	ADJ
admet-423	103	9	low	low	NOUN
admet-423	104	1	no	no	INTJ
admet-423	104	2	yes	yes	INTJ
admet-423	105	1	no	no	INTJ
admet-423	105	2	no	no	INTJ
admet-423	106	1	no	no	INTJ
admet-423	106	2	no	no	INTJ
admet-423	106	3	no	no	INTJ
admet-423	106	4	-11.77	-11.77	PUNCT
admet-423	106	5	n	n	CCONJ
admet-423	106	6	,	,	PUNCT
admet-423	106	7	n	n	CCONJ
admet-423	106	8	,	,	PUNCT
admet-423	106	9	n	n	CCONJ
admet-423	106	10	-	-	PUNCT
admet-423	106	11	trimethylchitosan	trimethylchitosan	NOUN
admet-423	106	12	low	low	NOUN
admet-423	107	1	no	no	INTJ
admet-423	107	2	yes	yes	INTJ
admet-423	108	1	no	no	INTJ
admet-423	108	2	no	no	INTJ
admet-423	109	1	no	no	INTJ
admet-423	109	2	no	no	INTJ
admet-423	110	1	no	no	INTJ
admet-423	110	2	-11.66	-11.66	NOUN
admet-423	110	3	chitosan	chitosan	NOUN
admet-423	110	4	-	-	PUNCT
admet-423	110	5	lactate	lactate	NOUN
admet-423	110	6	low	low	NOUN
admet-423	111	1	no	no	INTJ
admet-423	111	2	yes	yes	INTJ
admet-423	112	1	no	no	INTJ
admet-423	112	2	no	no	INTJ
admet-423	113	1	no	no	INTJ
admet-423	113	2	no	no	INTJ
admet-423	113	3	no	no	INTJ
admet-423	113	4	-12.27	-12.27	NOUN
admet-423	113	5	hydroxyethyl	hydroxyethyl	NOUN
admet-423	113	6	chitosan	chitosan	NOUN
admet-423	113	7	low	low	NOUN
admet-423	114	1	no	no	INTJ
admet-423	114	2	yes	yes	INTJ
admet-423	115	1	no	no	INTJ
admet-423	115	2	no	no	INTJ
admet-423	116	1	no	no	INTJ
admet-423	116	2	no	no	INTJ
admet-423	117	1	no	no	PRON
admet-423	117	2	-12.94	-12.94	PROPN
admet-423	117	3	hydroxypropyl	hydroxypropyl	NOUN
admet-423	117	4	chitosan	chitosan	ADJ
admet-423	117	5	low	low	NOUN
admet-423	118	1	no	no	INTJ
admet-423	118	2	yes	yes	INTJ
admet-423	119	1	no	no	INTJ
admet-423	119	2	no	no	INTJ
admet-423	120	1	no	no	INTJ
admet-423	120	2	no	no	INTJ
admet-423	121	1	no	no	INTJ
admet-423	121	2	-12.50	-12.50	PROPN
admet-423	121	3	dihydroxypropyl	dihydroxypropyl	NOUN
admet-423	121	4	chitosan	chitosan	NOUN
admet-423	121	5	low	low	NOUN
admet-423	122	1	no	no	INTJ
admet-423	122	2	yes	yes	INTJ
admet-423	123	1	no	no	INTJ
admet-423	123	2	no	no	INTJ
admet-423	124	1	no	no	INTJ
admet-423	124	2	no	no	INTJ
admet-423	124	3	no	no	INTJ
admet-423	124	4	-12.55	-12.55	PROPN
admet-423	124	5	n-(2	n-(2	NOUN
admet-423	124	6	-	-	PUNCT
admet-423	124	7	hydroxy)propyl-3trimethylammonium	hydroxy)propyl-3trimethylammonium	NOUN
admet-423	124	8	chitosan	chitosan	ADJ
admet-423	124	9	low	low	NOUN
admet-423	125	1	no	no	INTJ
admet-423	125	2	yes	yes	INTJ
admet-423	126	1	no	no	INTJ
admet-423	126	2	no	no	INTJ
admet-423	127	1	no	no	INTJ
admet-423	127	2	no	no	INTJ
admet-423	127	3	no	no	PRON
admet-423	128	1	-12.92	-12.92	NOUN
admet-423	128	2	o-(2	o-(2	NOUN
admet-423	128	3	-	-	PUNCT
admet-423	128	4	hydroxy)propyl-3trimethylammonium	hydroxy)propyl-3trimethylammonium	NOUN
admet-423	128	5	chitosan	chitosan	ADJ
admet-423	128	6	low	low	NOUN
admet-423	129	1	no	no	INTJ
admet-423	129	2	yes	yes	INTJ
admet-423	130	1	no	no	INTJ
admet-423	130	2	no	no	INTJ
admet-423	131	1	no	no	INTJ
admet-423	131	2	no	no	INTJ
admet-423	131	3	no	no	DET
admet-423	131	4	-12.92	-12.92	ADJ
admet-423	131	5	n-(4	n-(4	ADV
admet-423	131	6	-	-	PUNCT
admet-423	131	7	carboxybutyroyl	carboxybutyroyl	NOUN
admet-423	131	8	)	)	PUNCT
admet-423	132	1	chitosan	chitosan	NOUN
admet-423	132	2	low	low	NOUN
admet-423	133	1	no	no	INTJ
admet-423	133	2	yes	yes	INTJ
admet-423	134	1	no	no	INTJ
admet-423	134	2	no	no	INTJ
admet-423	135	1	no	no	INTJ
admet-423	135	2	no	no	INTJ
admet-423	135	3	no	no	DET
admet-423	135	4	-11.94	-11.94	PROPN
admet-423	135	5	n	n	CCONJ
admet-423	135	6	-	-	PUNCT
admet-423	135	7	trimethyl	trimethyl	NOUN
admet-423	135	8	chitosan	chitosan	NOUN
admet-423	135	9	low	low	NOUN
admet-423	136	1	no	no	INTJ
admet-423	136	2	yes	yes	INTJ
admet-423	137	1	no	no	INTJ
admet-423	137	2	no	no	INTJ
admet-423	138	1	no	no	INTJ
admet-423	138	2	no	no	INTJ
admet-423	138	3	no	no	DET
admet-423	138	4	-11.74	-11.74	ADJ
admet-423	138	5	results	result	NOUN
admet-423	138	6	concerning	concern	VERB
admet-423	138	7	side	side	NOUN
admet-423	138	8	/	/	SYM
admet-423	138	9	toxic	toxic	ADJ
admet-423	138	10	effects	effect	NOUN
admet-423	138	11	of	of	ADP
admet-423	138	12	compounds	compound	NOUN
admet-423	138	13	considered	consider	VERB
admet-423	138	14	in	in	ADP
admet-423	138	15	this	this	DET
admet-423	138	16	study	study	NOUN
admet-423	138	17	were	be	AUX
admet-423	138	18	obtained	obtain	VERB
admet-423	138	19	using	use	VERB
admet-423	138	20	pass	pass	NOUN
admet-423	138	21	online	online	ADV
admet-423	138	22	and	and	CCONJ
admet-423	138	23	are	be	AUX
admet-423	138	24	presented	present	VERB
admet-423	138	25	in	in	ADP
admet-423	138	26	table	table	NOUN
admet-423	138	27	4	4	NUM
admet-423	138	28	.	.	PUNCT
admet-423	139	1	when	when	SCONJ
admet-423	139	2	considering	consider	VERB
admet-423	139	3	the	the	DET
admet-423	139	4	predictions	prediction	NOUN
admet-423	139	5	made	make	VERB
admet-423	139	6	by	by	ADP
admet-423	139	7	pass	pass	VERB
admet-423	139	8	online	online	ADJ
admet-423	139	9	tool	tool	NOUN
admet-423	139	10	,	,	PUNCT
admet-423	139	11	we	we	PRON
admet-423	139	12	only	only	ADV
admet-423	139	13	took	take	VERB
admet-423	139	14	into	into	ADP
admet-423	139	15	account	account	NOUN
admet-423	139	16	those	those	DET
admet-423	139	17	results	result	NOUN
admet-423	139	18	with	with	ADP
admet-423	139	19	the	the	DET
admet-423	139	20	probability	probability	NOUN
admet-423	139	21	of	of	ADP
admet-423	139	22	a	a	DET
admet-423	139	23	compound	compound	NOUN
admet-423	139	24	to	to	PART
admet-423	139	25	be	be	AUX
admet-423	139	26	active	active	ADJ
admet-423	139	27	higher	high	ADJ
admet-423	139	28	than	than	ADP
admet-423	139	29	0.9	0.9	NUM
admet-423	139	30	.	.	PUNCT
admet-423	140	1	these	these	DET
admet-423	140	2	results	result	NOUN
admet-423	140	3	illustrate	illustrate	VERB
admet-423	140	4	that	that	SCONJ
admet-423	140	5	wsdc	wsdc	PROPN
admet-423	140	6	reflect	reflect	VERB
admet-423	140	7	fewer	few	ADJ
admet-423	140	8	and	and	CCONJ
admet-423	140	9	less	less	ADV
admet-423	140	10	important	important	ADJ
admet-423	140	11	side	side	ADJ
admet-423	140	12	/	/	SYM
admet-423	140	13	toxic	toxic	ADJ
admet-423	140	14	effects	effect	NOUN
admet-423	140	15	than	than	SCONJ
admet-423	140	16	deacetylated	deacetylated	ADJ
admet-423	140	17	and	and	CCONJ
admet-423	140	18	partially	partially	ADV
admet-423	140	19	deacetylated	deacetylate	VERB
admet-423	140	20	chitosan	chitosan	NOUN
admet-423	140	21	.	.	PUNCT
admet-423	141	1	carcinopred	carcinopre	VERB
admet-423	141	2	-	-	PUNCT
admet-423	141	3	el	el	PROPN
admet-423	141	4	tool	tool	PROPN
admet-423	141	5	reflects	reflect	VERB
admet-423	141	6	that	that	SCONJ
admet-423	141	7	all	all	DET
admet-423	141	8	considered	consider	VERB
admet-423	141	9	compounds	compound	NOUN
admet-423	141	10	belong	belong	VERB
admet-423	141	11	to	to	ADP
admet-423	141	12	the	the	DET
admet-423	141	13	non	non	ADJ
admet-423	141	14	-	-	ADJ
admet-423	141	15	carcinogen	carcinogen	ADJ
admet-423	141	16	class	class	NOUN
admet-423	141	17	of	of	ADP
admet-423	141	18	substances	substance	NOUN
admet-423	141	19	.	.	PUNCT
admet-423	142	1	pred	pre	VERB
admet-423	142	2	-	-	PUNCT
admet-423	142	3	herg	herg	PROPN
admet-423	142	4	results	result	NOUN
admet-423	142	5	also	also	ADV
admet-423	142	6	indicate	indicate	VERB
admet-423	142	7	that	that	SCONJ
admet-423	142	8	the	the	DET
admet-423	142	9	investigated	investigate	VERB
admet-423	142	10	compounds	compound	NOUN
admet-423	142	11	are	be	AUX
admet-423	142	12	non	non	ADJ
admet-423	142	13	-	-	NOUN
admet-423	142	14	blockers	blocker	NOUN
admet-423	142	15	for	for	ADP
admet-423	142	16	the	the	DET
admet-423	142	17	herg	herg	PROPN
admet-423	142	18	k+	k+	NOUN
admet-423	142	19	channels	channel	NOUN
admet-423	142	20	and	and	CCONJ
admet-423	142	21	do	do	AUX
admet-423	142	22	not	not	PART
admet-423	142	23	reflect	reflect	VERB
admet-423	142	24	cardiotoxicity	cardiotoxicity	NOUN
admet-423	142	25	.	.	PUNCT
admet-423	143	1	endocrine	endocrine	PROPN
admet-423	143	2	disruptome	disruptome	NOUN
admet-423	143	3	tool	tool	NOUN
admet-423	143	4	emphasizes	emphasize	VERB
admet-423	143	5	that	that	SCONJ
admet-423	143	6	wscd	wscd	NOUN
admet-423	143	7	considered	consider	VERB
admet-423	143	8	in	in	ADP
admet-423	143	9	this	this	DET
admet-423	143	10	study	study	NOUN
admet-423	143	11	have	have	VERB
admet-423	143	12	a	a	DET
admet-423	143	13	low	low	ADJ
admet-423	143	14	inhibitory	inhibitory	ADJ
admet-423	143	15	potential	potential	NOUN
admet-423	143	16	of	of	ADP
admet-423	143	17	endocrine	endocrine	ADJ
admet-423	143	18	system	system	NOUN
admet-423	143	19	-	-	PUNCT
admet-423	143	20	specific	specific	ADJ
admet-423	143	21	proteins	protein	NOUN
admet-423	143	22	.	.	PUNCT
admet-423	144	1	isvoran	isvoran	VERB
admet-423	144	2	,	,	PUNCT
admet-423	144	3	ciorsac	ciorsac	NOUN
admet-423	144	4	,	,	PUNCT
admet-423	144	5	ostafe	ostafe	NOUN
admet-423	144	6	admet	admet	PROPN
admet-423	144	7	&	&	CCONJ
admet-423	144	8	dmpk	dmpk	PROPN
admet-423	144	9	5(3	5(3	NUM
admet-423	144	10	)	)	PUNCT
admet-423	144	11	(	(	PUNCT
admet-423	144	12	2017	2017	NUM
admet-423	144	13	)	)	PUNCT
admet-423	144	14	192	192	NUM
admet-423	144	15	-	-	SYM
admet-423	144	16	200	200	NUM
admet-423	144	17	198	198	NUM
admet-423	144	18	table	table	NOUN
admet-423	144	19	4	4	NUM
admet-423	144	20	.	.	PUNCT
admet-423	144	21	toxic	toxic	ADJ
admet-423	144	22	effects	effect	NOUN
admet-423	144	23	of	of	ADP
admet-423	144	24	compounds	compound	NOUN
admet-423	144	25	considered	consider	VERB
admet-423	144	26	in	in	ADP
admet-423	144	27	this	this	DET
admet-423	144	28	study	study	NOUN
admet-423	144	29	compound	compound	NOUN
admet-423	144	30	toxic	toxic	ADJ
admet-423	144	31	effects	effect	NOUN
admet-423	144	32	deacetylated	deacetylate	VERB
admet-423	144	33	chitosan	chitosan	ADJ
admet-423	144	34	2	2	NUM
admet-423	144	35	units	unit	NOUN
admet-423	144	36	weight	weight	NOUN
admet-423	144	37	loss	loss	NOUN
admet-423	144	38	,	,	PUNCT
admet-423	144	39	acidosis	acidosis	NOUN
admet-423	144	40	,	,	PUNCT
admet-423	144	41	nausea	nausea	NOUN
admet-423	144	42	,	,	PUNCT
admet-423	144	43	gastrointestinal	gastrointestinal	ADJ
admet-423	144	44	toxicity	toxicity	NOUN
admet-423	144	45	,	,	PUNCT
admet-423	144	46	hematotoxicy	hematotoxicy	NOUN
admet-423	144	47	,	,	PUNCT
admet-423	144	48	respiratory	respiratory	ADJ
admet-423	144	49	failure	failure	NOUN
admet-423	144	50	,	,	PUNCT
admet-423	144	51	reproductive	reproductive	ADJ
admet-423	144	52	dysfunction	dysfunction	NOUN
admet-423	144	53	,	,	PUNCT
admet-423	144	54	neurotoxicity	neurotoxicity	NOUN
admet-423	144	55	partially	partially	ADV
admet-423	144	56	deacetylated	deacetylate	VERB
admet-423	144	57	chitosan	chitosan	ADJ
admet-423	144	58	2	2	NUM
admet-423	144	59	units	unit	NOUN
admet-423	144	60	weight	weight	NOUN
admet-423	144	61	loss	loss	NOUN
admet-423	144	62	,	,	PUNCT
admet-423	144	63	acidosis	acidosis	NOUN
admet-423	144	64	,	,	PUNCT
admet-423	144	65	nausea	nausea	NOUN
admet-423	144	66	,	,	PUNCT
admet-423	144	67	gastrointestinal	gastrointestinal	ADJ
admet-423	144	68	toxicity	toxicity	NOUN
admet-423	144	69	,	,	PUNCT
admet-423	144	70	nephrotoxicity	nephrotoxicity	NOUN
admet-423	144	71	,	,	PUNCT
admet-423	144	72	hematotoxicity	hematotoxicity	NOUN
admet-423	144	73	,	,	PUNCT
admet-423	144	74	thrombocytopenia	thrombocytopenia	PROPN
admet-423	144	75	,	,	PUNCT
admet-423	144	76	pain	pain	NOUN
admet-423	144	77	,	,	PUNCT
admet-423	144	78	respiratory	respiratory	ADJ
admet-423	144	79	failure	failure	NOUN
admet-423	144	80	,	,	PUNCT
admet-423	144	81	cyanosis	cyanosis	NOUN
admet-423	144	82	,	,	PUNCT
admet-423	144	83	necrosis	necrosis	NOUN
admet-423	144	84	,	,	PUNCT
admet-423	144	85	reproductive	reproductive	ADJ
admet-423	144	86	dysfunction	dysfunction	NOUN
admet-423	144	87	,	,	PUNCT
admet-423	144	88	neurotoxicity	neurotoxicity	NOUN
admet-423	144	89	o	o	NOUN
admet-423	144	90	-	-	NOUN
admet-423	144	91	carboxymethyl	carboxymethyl	NOUN
admet-423	144	92	chitosan	chitosan	NOUN
admet-423	144	93	(	(	PUNCT
admet-423	144	94	1	1	NUM
admet-423	144	95	unit	unit	NOUN
admet-423	144	96	)	)	PUNCT
admet-423	145	1	pa<0.9	pa<0.9	PROPN
admet-423	145	2	n	n	CCONJ
admet-423	145	3	,	,	PUNCT
admet-423	145	4	n	n	CCONJ
admet-423	145	5	-	-	PUNCT
admet-423	145	6	carboxymethyl	carboxymethyl	NOUN
admet-423	145	7	chitosan	chitosan	NOUN
admet-423	145	8	(	(	PUNCT
admet-423	145	9	1	1	NUM
admet-423	145	10	unit	unit	NOUN
admet-423	145	11	)	)	PUNCT
admet-423	146	1	pa<0.9	pa<0.9	PROPN
admet-423	146	2	n	n	CCONJ
admet-423	146	3	,	,	PUNCT
admet-423	146	4	o	o	NOUN
admet-423	146	5	-	-	NOUN
admet-423	146	6	carboxymethyl	carboxymethyl	NOUN
admet-423	146	7	chitosan	chitosan	NOUN
admet-423	146	8	(	(	PUNCT
admet-423	146	9	1	1	NUM
admet-423	146	10	unit	unit	NOUN
admet-423	146	11	)	)	PUNCT
admet-423	147	1	pa<0.9	pa<0.9	PROPN
admet-423	147	2	n	n	CCONJ
admet-423	147	3	,	,	PUNCT
admet-423	147	4	n	n	CCONJ
admet-423	147	5	,	,	PUNCT
admet-423	147	6	o	o	NOUN
admet-423	147	7	-	-	NOUN
admet-423	147	8	carboxymethyl	carboxymethyl	NOUN
admet-423	147	9	chitosan	chitosan	PROPN
admet-423	147	10	pa<0.9	pa<0.9	PROPN
admet-423	147	11	n	n	CCONJ
admet-423	147	12	-	-	PUNCT
admet-423	147	13	carboxymethyl	carboxymethyl	NOUN
admet-423	147	14	chitosan	chitosan	ADJ
admet-423	147	15	weight	weight	NOUN
admet-423	147	16	loss	loss	NOUN
admet-423	147	17	,	,	PUNCT
admet-423	147	18	acidosis	acidosis	NOUN
admet-423	147	19	,	,	PUNCT
admet-423	147	20	respiratory	respiratory	ADJ
admet-423	147	21	failure	failure	NOUN
admet-423	147	22	,	,	PUNCT
admet-423	147	23	inflammation	inflammation	NOUN
admet-423	147	24	n	n	CCONJ
admet-423	147	25	,	,	PUNCT
admet-423	147	26	n	n	CCONJ
admet-423	147	27	,	,	PUNCT
admet-423	147	28	n	n	CCONJ
admet-423	147	29	-	-	PUNCT
admet-423	147	30	trimethyl	trimethyl	ADV
admet-423	147	31	-	-	PUNCT
admet-423	147	32	chitosan	chitosan	NOUN
admet-423	147	33	weight	weight	NOUN
admet-423	147	34	loss	loss	NOUN
admet-423	147	35	,	,	PUNCT
admet-423	147	36	acidosis	acidosis	NOUN
admet-423	147	37	,	,	PUNCT
admet-423	147	38	respiratory	respiratory	ADJ
admet-423	147	39	failure	failure	NOUN
admet-423	147	40	,	,	PUNCT
admet-423	147	41	gastrointestinal	gastrointestinal	ADJ
admet-423	147	42	toxicity	toxicity	NOUN
admet-423	147	43	chitosan	chitosan	NOUN
admet-423	147	44	-	-	PUNCT
admet-423	147	45	lactate	lactate	NOUN
admet-423	147	46	acidosis	acidosis	NOUN
admet-423	147	47	,	,	PUNCT
admet-423	147	48	weight	weight	NOUN
admet-423	147	49	loss	loss	NOUN
admet-423	147	50	,	,	PUNCT
admet-423	147	51	nausea	nausea	NOUN
admet-423	147	52	,	,	PUNCT
admet-423	147	53	hematotoxicity	hematotoxicity	NOUN
admet-423	147	54	,	,	PUNCT
admet-423	147	55	gastrointestinal	gastrointestinal	ADJ
admet-423	147	56	toxicity	toxicity	NOUN
admet-423	147	57	,	,	PUNCT
admet-423	147	58	hyperglycemic	hyperglycemic	ADJ
admet-423	147	59	,	,	PUNCT
admet-423	147	60	respiratory	respiratory	ADJ
admet-423	147	61	failure	failure	NOUN
admet-423	147	62	,	,	PUNCT
admet-423	147	63	cyanoses	cyanose	NOUN
admet-423	147	64	,	,	PUNCT
admet-423	147	65	leukopenia	leukopenia	PROPN
admet-423	147	66	hydroxyethyl	hydroxyethyl	PROPN
admet-423	147	67	chitosan	chitosan	PROPN
admet-423	147	68	hematotoxicity	hematotoxicity	NOUN
admet-423	147	69	,	,	PUNCT
admet-423	147	70	nephrotoxicity	nephrotoxicity	NOUN
admet-423	147	71	,	,	PUNCT
admet-423	147	72	respiratory	respiratory	ADJ
admet-423	147	73	failure	failure	NOUN
admet-423	147	74	,	,	PUNCT
admet-423	147	75	acidosis	acidosis	NOUN
admet-423	147	76	,	,	PUNCT
admet-423	147	77	thrombocytopenia	thrombocytopenia	PROPN
admet-423	147	78	,	,	PUNCT
admet-423	147	79	allergic	allergic	ADJ
admet-423	147	80	dermatitis	dermatitis	NOUN
admet-423	147	81	,	,	PUNCT
admet-423	147	82	gastrointestinal	gastrointestinal	ADJ
admet-423	147	83	toxicity	toxicity	NOUN
admet-423	147	84	,	,	PUNCT
admet-423	147	85	nausea	nausea	NOUN
admet-423	147	86	,	,	PUNCT
admet-423	147	87	asthma	asthma	NOUN
admet-423	147	88	,	,	PUNCT
admet-423	147	89	necrosis	necrosis	NOUN
admet-423	147	90	,	,	PUNCT
admet-423	147	91	cyanosis	cyanosis	NOUN
admet-423	147	92	,	,	PUNCT
admet-423	147	93	leukopenia	leukopenia	NOUN
admet-423	147	94	,	,	PUNCT
admet-423	147	95	neurotoxicity	neurotoxicity	NOUN
admet-423	147	96	hydroxypropyl	hydroxypropyl	NOUN
admet-423	147	97	chitosan	chitosan	NOUN
admet-423	147	98	hematotoxicity	hematotoxicity	NOUN
admet-423	147	99	,	,	PUNCT
admet-423	147	100	acidosis	acidosis	NOUN
admet-423	147	101	,	,	PUNCT
admet-423	147	102	nausea	nausea	NOUN
admet-423	147	103	,	,	PUNCT
admet-423	147	104	gastrointestinal	gastrointestinal	ADJ
admet-423	147	105	toxicity	toxicity	NOUN
admet-423	147	106	,	,	PUNCT
admet-423	147	107	dermatitis	dermatitis	NOUN
admet-423	147	108	,	,	PUNCT
admet-423	147	109	nephrotoxicity	nephrotoxicity	NOUN
admet-423	147	110	dihydroxypropyl	dihydroxypropyl	NOUN
admet-423	147	111	chitosan	chitosan	NOUN
admet-423	147	112	acidosis	acidosis	NOUN
admet-423	147	113	,	,	PUNCT
admet-423	147	114	nausea	nausea	NOUN
admet-423	147	115	,	,	PUNCT
admet-423	147	116	gastrointestinal	gastrointestinal	ADJ
admet-423	147	117	toxicity	toxicity	NOUN
admet-423	147	118	,	,	PUNCT
admet-423	147	119	respiratory	respiratory	ADJ
admet-423	147	120	failure	failure	NOUN
admet-423	147	121	n-(2	n-(2	NOUN
admet-423	147	122	-	-	PUNCT
admet-423	147	123	hydroxy)propyl-3trimethylammonium	hydroxy)propyl-3trimethylammonium	NOUN
admet-423	147	124	chitosan	chitosan	NOUN
admet-423	147	125	n	n	CCONJ
admet-423	147	126	/	/	SYM
admet-423	147	127	a	a	DET
admet-423	147	128	o-(2	o-(2	NOUN
admet-423	147	129	-	-	PUNCT
admet-423	147	130	hydroxy)propyl-3trimethylammonium	hydroxy)propyl-3trimethylammonium	NOUN
admet-423	147	131	chitosan	chitosan	NOUN
admet-423	147	132	n	n	CCONJ
admet-423	147	133	/	/	SYM
admet-423	147	134	a	a	DET
admet-423	147	135	n-(4	n-(4	ADV
admet-423	147	136	-	-	PUNCT
admet-423	147	137	carboxybutyroyl	carboxybutyroyl	NOUN
admet-423	147	138	)	)	PUNCT
admet-423	147	139	chitosan	chitosan	NOUN
admet-423	147	140	weight	weight	NOUN
admet-423	147	141	loss	loss	NOUN
admet-423	147	142	,	,	PUNCT
admet-423	147	143	acidosis	acidosis	NOUN
admet-423	147	144	,	,	PUNCT
admet-423	147	145	hematotoxicity	hematotoxicity	NOUN
admet-423	147	146	,	,	PUNCT
admet-423	147	147	nausea	nausea	NOUN
admet-423	147	148	,	,	PUNCT
admet-423	147	149	gastrointestinal	gastrointestinal	ADJ
admet-423	147	150	toxicity	toxicity	NOUN
admet-423	147	151	,	,	PUNCT
admet-423	147	152	neurotoxicity	neurotoxicity	NOUN
admet-423	147	153	,	,	PUNCT
admet-423	147	154	respiratory	respiratory	ADJ
admet-423	147	155	failure	failure	NOUN
admet-423	147	156	n	n	CCONJ
admet-423	147	157	-	-	PUNCT
admet-423	147	158	trimethyl	trimethyl	NOUN
admet-423	147	159	chitosan	chitosan	NOUN
admet-423	147	160	n	n	CCONJ
admet-423	147	161	/	/	SYM
admet-423	147	162	a	a	DET
admet-423	147	163	conclusions	conclusion	NOUN
admet-423	147	164	as	as	SCONJ
admet-423	147	165	there	there	PRON
admet-423	147	166	are	be	VERB
admet-423	147	167	limited	limit	VERB
admet-423	147	168	experimental	experimental	ADJ
admet-423	147	169	in	in	ADP
admet-423	147	170	vivo	vivo	ADJ
admet-423	147	171	studies	study	NOUN
admet-423	147	172	concerning	concern	VERB
admet-423	147	173	the	the	DET
admet-423	147	174	pharmacological	pharmacological	ADJ
admet-423	147	175	and	and	CCONJ
admet-423	147	176	toxicological	toxicological	ADJ
admet-423	147	177	effects	effect	NOUN
admet-423	147	178	of	of	ADP
admet-423	147	179	chitosan	chitosan	NOUN
admet-423	147	180	and	and	CCONJ
admet-423	147	181	its	its	PRON
admet-423	147	182	wsd	wsd	PROPN
admet-423	147	183	on	on	ADP
admet-423	147	184	humans	human	NOUN
admet-423	147	185	,	,	PUNCT
admet-423	147	186	computational	computational	ADJ
admet-423	147	187	predictions	prediction	NOUN
admet-423	147	188	of	of	ADP
admet-423	147	189	their	their	PRON
admet-423	147	190	pharmacokinetics	pharmacokinetic	NOUN
admet-423	147	191	and	and	CCONJ
admet-423	147	192	adverse	adverse	ADJ
admet-423	147	193	effects	effect	NOUN
admet-423	147	194	may	may	AUX
admet-423	147	195	provide	provide	VERB
admet-423	147	196	useful	useful	ADJ
admet-423	147	197	information	information	NOUN
admet-423	147	198	.	.	PUNCT
admet-423	148	1	chitosan	chitosan	NOUN
admet-423	148	2	and	and	CCONJ
admet-423	148	3	its	its	PRON
admet-423	148	4	derivatives	derivative	NOUN
admet-423	148	5	considered	consider	VERB
admet-423	148	6	in	in	ADP
admet-423	148	7	this	this	DET
admet-423	148	8	study	study	NOUN
admet-423	148	9	reflect	reflect	VERB
admet-423	148	10	low	low	ADJ
admet-423	148	11	skin	skin	NOUN
admet-423	148	12	permeability	permeability	NOUN
admet-423	148	13	and	and	CCONJ
admet-423	148	14	low	low	ADJ
admet-423	148	15	inhibitory	inhibitory	ADJ
admet-423	148	16	potential	potential	NOUN
admet-423	148	17	for	for	ADP
admet-423	148	18	the	the	DET
admet-423	148	19	proteins	protein	NOUN
admet-423	148	20	specific	specific	ADJ
admet-423	148	21	to	to	ADP
admet-423	148	22	the	the	DET
admet-423	148	23	endocrine	endocrine	ADJ
admet-423	148	24	system	system	NOUN
admet-423	148	25	.	.	PUNCT
admet-423	149	1	they	they	PRON
admet-423	149	2	are	be	AUX
admet-423	149	3	not	not	PART
admet-423	149	4	able	able	ADJ
admet-423	149	5	to	to	PART
admet-423	149	6	penetrate	penetrate	VERB
admet-423	149	7	the	the	DET
admet-423	149	8	blood	blood	NOUN
admet-423	149	9	brain	brain	NOUN
admet-423	149	10	barrier	barrier	NOUN
admet-423	149	11	and	and	CCONJ
admet-423	149	12	to	to	PART
admet-423	149	13	affect	affect	VERB
admet-423	149	14	the	the	DET
admet-423	149	15	central	central	ADJ
admet-423	149	16	nervous	nervous	ADJ
admet-423	149	17	system	system	NOUN
admet-423	149	18	and	and	CCONJ
admet-423	149	19	they	they	PRON
admet-423	149	20	are	be	AUX
admet-423	149	21	not	not	PART
admet-423	149	22	predicted	predict	VERB
admet-423	149	23	to	to	PART
admet-423	149	24	have	have	VERB
admet-423	149	25	an	an	DET
admet-423	149	26	inhibitory	inhibitory	ADJ
admet-423	149	27	potential	potential	NOUN
admet-423	149	28	for	for	ADP
admet-423	149	29	the	the	DET
admet-423	149	30	enzymes	enzyme	NOUN
admet-423	149	31	of	of	ADP
admet-423	149	32	the	the	DET
admet-423	149	33	cytochrome	cytochrome	NOUN
admet-423	149	34	p450	p450	PROPN
admet-423	149	35	involved	involve	VERB
admet-423	149	36	in	in	ADP
admet-423	149	37	drugs	drug	NOUN
admet-423	149	38	and	and	CCONJ
admet-423	149	39	other	other	ADJ
admet-423	149	40	xenobiotics	xenobiotics	PROPN
admet-423	149	41	metabolism	metabolism	NOUN
admet-423	149	42	.	.	PUNCT
admet-423	150	1	they	they	PRON
admet-423	150	2	are	be	AUX
admet-423	150	3	predicted	predict	VERB
admet-423	150	4	to	to	PART
admet-423	150	5	be	be	AUX
admet-423	150	6	substrates	substrate	NOUN
admet-423	150	7	for	for	ADP
admet-423	150	8	the	the	DET
admet-423	150	9	p	p	NOUN
admet-423	150	10	-	-	PUNCT
admet-423	150	11	gp	gp	NOUN
admet-423	150	12	protein	protein	NOUN
admet-423	150	13	and	and	CCONJ
admet-423	150	14	it	it	PRON
admet-423	150	15	illustrate	illustrate	VERB
admet-423	150	16	that	that	SCONJ
admet-423	150	17	their	their	PRON
admet-423	150	18	systemic	systemic	ADJ
admet-423	150	19	exposure	exposure	NOUN
admet-423	150	20	could	could	AUX
admet-423	150	21	be	be	AUX
admet-423	150	22	reduced	reduce	VERB
admet-423	150	23	.	.	PUNCT
admet-423	151	1	by	by	ADP
admet-423	151	2	comparison	comparison	NOUN
admet-423	151	3	to	to	ADP
admet-423	151	4	chitosan	chitosan	NOUN
admet-423	151	5	and	and	CCONJ
admet-423	151	6	deacetylated	deacetylate	VERB
admet-423	151	7	chitosan	chitosan	NOUN
admet-423	151	8	,	,	PUNCT
admet-423	151	9	some	some	DET
admet-423	151	10	wsdc	wsdc	NOUN
admet-423	151	11	show	show	VERB
admet-423	151	12	good	good	ADJ
admet-423	151	13	oral	oral	ADJ
admet-423	151	14	bioavailability	bioavailability	NOUN
admet-423	151	15	.	.	PUNCT
admet-423	152	1	furthermore	furthermore	ADV
admet-423	152	2	,	,	PUNCT
admet-423	152	3	the	the	DET
admet-423	152	4	investigated	investigate	VERB
admet-423	152	5	compounds	compound	NOUN
admet-423	152	6	do	do	AUX
admet-423	152	7	not	not	PART
admet-423	152	8	reveal	reveal	VERB
admet-423	152	9	carcinogenic	carcinogenic	ADJ
admet-423	152	10	potential	potential	ADJ
admet-423	152	11	and	and	CCONJ
admet-423	152	12	cardiac	cardiac	ADJ
admet-423	152	13	toxicity	toxicity	NOUN
admet-423	152	14	,	,	PUNCT
admet-423	152	15	but	but	CCONJ
admet-423	152	16	they	they	PRON
admet-423	152	17	are	be	AUX
admet-423	152	18	predicted	predict	VERB
admet-423	152	19	to	to	PART
admet-423	152	20	induce	induce	VERB
admet-423	152	21	phospholipidosis	phospholipidosis	NOUN
admet-423	152	22	and	and	CCONJ
admet-423	152	23	to	to	PART
admet-423	152	24	have	have	VERB
admet-423	152	25	some	some	DET
admet-423	152	26	adverse	adverse	ADJ
admet-423	152	27	effects	effect	NOUN
admet-423	152	28	:	:	PUNCT
admet-423	152	29	weight	weight	NOUN
admet-423	152	30	loss	loss	NOUN
admet-423	152	31	,	,	PUNCT
admet-423	152	32	acidosis	acidosis	NOUN
admet-423	152	33	,	,	PUNCT
admet-423	152	34	gastrointestinal	gastrointestinal	ADJ
admet-423	152	35	toxicity	toxicity	NOUN
admet-423	152	36	,	,	PUNCT
admet-423	152	37	respiratory	respiratory	ADJ
admet-423	152	38	failure	failure	NOUN
admet-423	152	39	.	.	PUNCT
admet-423	153	1	some	some	PRON
admet-423	153	2	of	of	ADP
admet-423	153	3	the	the	DET
admet-423	153	4	predicted	predict	VERB
admet-423	153	5	pharmacological	pharmacological	NOUN
admet-423	153	6	and	and	CCONJ
admet-423	153	7	toxicological	toxicological	ADJ
admet-423	153	8	profiles	profile	NOUN
admet-423	153	9	of	of	ADP
admet-423	153	10	the	the	DET
admet-423	153	11	considered	consider	VERB
admet-423	153	12	wsdc	wsdc	NOUN
admet-423	153	13	are	be	AUX
admet-423	153	14	in	in	ADP
admet-423	153	15	good	good	ADJ
admet-423	153	16	agreement	agreement	NOUN
admet-423	153	17	with	with	ADP
admet-423	153	18	a	a	DET
admet-423	153	19	few	few	ADJ
admet-423	153	20	experimental	experimental	ADJ
admet-423	153	21	studies	study	NOUN
admet-423	153	22	revealing	reveal	VERB
admet-423	153	23	that	that	SCONJ
admet-423	153	24	wsdc	wsdc	PROPN
admet-423	153	25	have	have	VERB
admet-423	153	26	no	no	DET
admet-423	153	27	or	or	CCONJ
admet-423	153	28	low	low	ADJ
admet-423	153	29	cytotoxicity	cytotoxicity	NOUN
admet-423	153	30	[	[	X
admet-423	153	31	28	28	NUM
admet-423	153	32	,	,	PUNCT
admet-423	153	33	29	29	NUM
admet-423	153	34	]	]	PUNCT
admet-423	153	35	,	,	PUNCT
admet-423	153	36	no	no	DET
admet-423	153	37	genotoxicity	genotoxicity	NOUN
admet-423	153	38	[	[	X
admet-423	153	39	28	28	NUM
admet-423	153	40	]	]	PUNCT
admet-423	153	41	,	,	PUNCT
admet-423	153	42	have	have	VERB
admet-423	153	43	fatand	fatand	VERB
admet-423	153	44	cholesterol	cholesterol	NOUN
admet-423	153	45	-	-	PUNCT
admet-423	153	46	binding	bind	VERB
admet-423	153	47	capacities	capacity	NOUN
admet-423	153	48	producing	produce	VERB
admet-423	153	49	weight	weight	NOUN
admet-423	153	50	loss	loss	NOUN
admet-423	153	51	[	[	X
admet-423	153	52	30	30	NUM
admet-423	153	53	]	]	PUNCT
admet-423	153	54	.	.	PUNCT
admet-423	154	1	their	their	PRON
admet-423	154	2	side	side	NOUN
admet-423	154	3	effects	effect	NOUN
admet-423	154	4	increase	increase	VERB
admet-423	154	5	with	with	ADP
admet-423	154	6	the	the	DET
admet-423	154	7	molecular	molecular	ADJ
admet-423	154	8	weight	weight	NOUN
admet-423	154	9	and	and	CCONJ
admet-423	154	10	degree	degree	NOUN
admet-423	154	11	of	of	ADP
admet-423	154	12	deacetylation	deacetylation	NOUN
admet-423	154	13	[	[	X
admet-423	154	14	31	31	NUM
admet-423	154	15	]	]	PUNCT
admet-423	154	16	.	.	PUNCT
admet-423	155	1	this	this	DET
admet-423	155	2	agreement	agreement	NOUN
admet-423	155	3	strengthens	strengthen	VERB
admet-423	155	4	the	the	DET
admet-423	155	5	outcomes	outcome	NOUN
admet-423	155	6	of	of	ADP
admet-423	155	7	this	this	DET
admet-423	155	8	study	study	NOUN
admet-423	155	9	and	and	CCONJ
admet-423	155	10	illustrates	illustrate	VERB
admet-423	155	11	the	the	DET
admet-423	155	12	utility	utility	NOUN
admet-423	155	13	of	of	ADP
admet-423	155	14	the	the	DET
admet-423	155	15	methods	method	NOUN
admet-423	155	16	.	.	PUNCT
admet-423	156	1	admet	admet	PROPN
admet-423	156	2	&	&	CCONJ
admet-423	156	3	dmpk	dmpk	PROPN
admet-423	156	4	5(3	5(3	NUM
admet-423	156	5	)	)	PUNCT
admet-423	156	6	(	(	PUNCT
admet-423	156	7	2017	2017	NUM
admet-423	156	8	)	)	PUNCT
admet-423	156	9	192	192	NUM
admet-423	156	10	-	-	SYM
admet-423	156	11	200	200	NUM
admet-423	156	12	admet	admet	NOUN
admet-423	156	13	of	of	ADP
admet-423	156	14	chitosan	chitosan	NOUN
admet-423	156	15	derivatives	derivative	NOUN
admet-423	156	16	doi	doi	NOUN
admet-423	156	17	:	:	PUNCT
admet-423	156	18	10.5599	10.5599	NUM
admet-423	156	19	/	/	SYM
admet-423	156	20	admet.5.3.423	admet.5.3.423	PRON
admet-423	156	21	199	199	NUM
admet-423	156	22	to	to	ADP
admet-423	156	23	the	the	DET
admet-423	156	24	best	good	ADJ
admet-423	156	25	of	of	ADP
admet-423	156	26	our	our	PRON
admet-423	156	27	knowledge	knowledge	NOUN
admet-423	156	28	,	,	PUNCT
admet-423	156	29	this	this	PRON
admet-423	156	30	is	be	AUX
admet-423	156	31	a	a	DET
admet-423	156	32	first	first	ADJ
admet-423	156	33	study	study	NOUN
admet-423	156	34	dealing	deal	VERB
admet-423	156	35	with	with	ADP
admet-423	156	36	the	the	DET
admet-423	156	37	adme	adme	NOUN
admet-423	156	38	-	-	PUNCT
admet-423	156	39	tox	tox	NOUN
admet-423	156	40	properties	property	NOUN
admet-423	156	41	of	of	ADP
admet-423	156	42	chitosan	chitosan	NOUN
admet-423	156	43	and	and	CCONJ
admet-423	156	44	some	some	PRON
admet-423	156	45	of	of	ADP
admet-423	156	46	its	its	PRON
admet-423	156	47	water	water	NOUN
admet-423	156	48	soluble	soluble	ADJ
admet-423	156	49	derivatives	derivative	NOUN
admet-423	156	50	that	that	PRON
admet-423	156	51	are	be	AUX
admet-423	156	52	used	use	VERB
admet-423	156	53	for	for	ADP
admet-423	156	54	wound	wound	ADJ
admet-423	156	55	healing	healing	NOUN
admet-423	156	56	.	.	PUNCT
admet-423	157	1	chitosan	chitosan	NOUN
admet-423	157	2	and	and	CCONJ
admet-423	157	3	its	its	PRON
admet-423	157	4	water	water	NOUN
admet-423	157	5	-	-	PUNCT
admet-423	157	6	soluble	soluble	ADJ
admet-423	157	7	derivatives	derivative	NOUN
admet-423	157	8	are	be	AUX
admet-423	157	9	approved	approve	VERB
admet-423	157	10	by	by	ADP
admet-423	157	11	the	the	DET
admet-423	157	12	us	us	PROPN
admet-423	157	13	food	food	NOUN
admet-423	157	14	and	and	CCONJ
admet-423	157	15	drug	drug	PROPN
admet-423	157	16	administration	administration	NOUN
admet-423	157	17	only	only	ADV
admet-423	157	18	to	to	PART
admet-423	157	19	be	be	AUX
admet-423	157	20	used	use	VERB
admet-423	157	21	for	for	ADP
admet-423	157	22	wound	wound	ADJ
admet-423	157	23	healing	healing	NOUN
admet-423	157	24	.	.	PUNCT
admet-423	158	1	as	as	SCONJ
admet-423	158	2	they	they	PRON
admet-423	158	3	reflect	reflect	VERB
admet-423	158	4	low	low	ADJ
admet-423	158	5	skin	skin	NOUN
admet-423	158	6	penetration	penetration	NOUN
admet-423	158	7	,	,	PUNCT
admet-423	158	8	people	people	NOUN
admet-423	158	9	being	be	AUX
admet-423	158	10	treated	treat	VERB
admet-423	158	11	with	with	ADP
admet-423	158	12	these	these	DET
admet-423	158	13	compounds	compound	NOUN
admet-423	158	14	reveal	reveal	VERB
admet-423	158	15	only	only	ADV
admet-423	158	16	a	a	DET
admet-423	158	17	low	low	ADJ
admet-423	158	18	degree	degree	NOUN
admet-423	158	19	of	of	ADP
admet-423	158	20	exposure	exposure	NOUN
admet-423	158	21	.	.	PUNCT
admet-423	159	1	the	the	DET
admet-423	159	2	obtained	obtain	VERB
admet-423	159	3	information	information	NOUN
admet-423	159	4	is	be	AUX
admet-423	159	5	important	important	ADJ
admet-423	159	6	especially	especially	ADV
admet-423	159	7	for	for	SCONJ
admet-423	159	8	people	people	NOUN
admet-423	159	9	manufacturing	manufacture	VERB
admet-423	159	10	and	and	CCONJ
admet-423	159	11	handling	handle	VERB
admet-423	159	12	these	these	DET
admet-423	159	13	compounds	compound	NOUN
admet-423	159	14	being	be	AUX
admet-423	159	15	occupationally	occupationally	ADV
admet-423	159	16	exposed	expose	VERB
admet-423	159	17	to	to	ADP
admet-423	159	18	these	these	DET
admet-423	159	19	chemicals	chemical	NOUN
admet-423	159	20	.	.	PUNCT
admet-423	160	1	acknowledgements	acknowledgement	NOUN
admet-423	160	2	:	:	PUNCT
admet-423	160	3	this	this	DET
admet-423	160	4	work	work	NOUN
admet-423	160	5	is	be	AUX
admet-423	160	6	supported	support	VERB
admet-423	160	7	by	by	ADP
admet-423	160	8	grant	grant	NOUN
admet-423	160	9	pniii	pniii	NOUN
admet-423	160	10	-	-	PUNCT
admet-423	160	11	p3	p3	NOUN
admet-423	160	12	-	-	PUNCT
admet-423	160	13	284	284	NUM
admet-423	160	14	,	,	PUNCT
admet-423	160	15	chitowound	chitowound	ADJ
admet-423	160	16	biotechnological	biotechnological	ADJ
admet-423	160	17	tools	tool	NOUN
admet-423	160	18	implementation	implementation	NOUN
admet-423	160	19	for	for	ADP
admet-423	160	20	new	new	ADJ
admet-423	160	21	wound	wound	NOUN
admet-423	160	22	healing	healing	NOUN
admet-423	160	23	applications	application	NOUN
admet-423	160	24	of	of	ADP
admet-423	160	25	byproducts	byproduct	NOUN
admet-423	160	26	from	from	ADP
admet-423	160	27	the	the	DET
admet-423	160	28	crustacean	crustacean	ADJ
admet-423	160	29	seafood	seafood	NOUN
admet-423	160	30	processing	processing	NOUN
admet-423	160	31	industry	industry	NOUN
admet-423	160	32	.	.	PUNCT
admet-423	161	1	references	reference	NOUN
admet-423	161	2	[	[	X
admet-423	161	3	1	1	NUM
admet-423	161	4	]	]	PUNCT
admet-423	161	5	r.	r.	PROPN
admet-423	161	6	riva	riva	PROPN
admet-423	161	7	,	,	PUNCT
admet-423	161	8	h.	h.	PROPN
admet-423	161	9	ragelle	ragelle	PROPN
admet-423	161	10	,	,	PUNCT
admet-423	161	11	a.	a.	PROPN
admet-423	161	12	des	des	X
admet-423	161	13	rieux	rieux	PROPN
admet-423	161	14	,	,	PUNCT
admet-423	161	15	n.	n.	NOUN
admet-423	161	16	duhem	duhem	PROPN
admet-423	161	17	,	,	PUNCT
admet-423	161	18	c.	c.	PROPN
admet-423	161	19	jérôme	jérôme	PROPN
admet-423	161	20	,	,	PUNCT
admet-423	161	21	v.	v.	CCONJ
admet-423	161	22	préat	préat	NOUN
admet-423	161	23	,	,	PUNCT
admet-423	161	24	advanced	advanced	ADJ
admet-423	161	25	polymers	polymer	NOUN
admet-423	161	26	science	science	NOUN
admet-423	161	27	244	244	NUM
admet-423	161	28	(	(	PUNCT
admet-423	161	29	2011	2011	NUM
admet-423	161	30	)	)	PUNCT
admet-423	161	31	19–44	19–44	NUM
admet-423	161	32	;	;	PUNCT
admet-423	161	33	https://link.springer.com/chapter/10.1007%2f12_2011_137	https://link.springer.com/chapter/10.1007%2f12_2011_137	NOUN
admet-423	161	34	.	.	PUNCT
admet-423	162	1	[	[	X
admet-423	162	2	2	2	NUM
admet-423	162	3	]	]	X
admet-423	162	4	r.c	r.c	PROPN
admet-423	162	5	.	.	PROPN
admet-423	162	6	cheung	cheung	PROPN
admet-423	162	7	,	,	PUNCT
admet-423	162	8	t.b	t.b	PROPN
admet-423	162	9	.	.	PROPN
admet-423	162	10	ng	ng	PROPN
admet-423	162	11	,	,	PUNCT
admet-423	162	12	j.h	j.h	PROPN
admet-423	162	13	.	.	PROPN
admet-423	162	14	wong	wong	PROPN
admet-423	162	15	,	,	PUNCT
admet-423	162	16	w.y	w.y	PROPN
admet-423	162	17	.	.	PROPN
admet-423	162	18	chan	chan	PROPN
admet-423	162	19	,	,	PUNCT
admet-423	162	20	marine	marine	ADJ
admet-423	162	21	drugs	drug	NOUN
admet-423	162	22	13	13	NUM
admet-423	162	23	(	(	PUNCT
admet-423	162	24	2015	2015	NUM
admet-423	162	25	)	)	PUNCT
admet-423	162	26	5156	5156	NUM
admet-423	162	27	-	-	SYM
admet-423	162	28	5186	5186	NUM
admet-423	162	29	;	;	PUNCT
admet-423	162	30	http://www.mdpi.com/1660-3397/13/8/5156	http://www.mdpi.com/1660-3397/13/8/5156	PROPN
admet-423	162	31	.	.	PUNCT
admet-423	163	1	[	[	X
admet-423	163	2	3	3	X
admet-423	163	3	]	]	X
admet-423	163	4	m.d	m.d	PROPN
admet-423	163	5	.	.	PROPN
admet-423	163	6	gades	gades	PROPN
admet-423	163	7	,	,	PUNCT
admet-423	163	8	j.s	j.s	PROPN
admet-423	163	9	.	.	PROPN
admet-423	163	10	stern	stern	PROPN
admet-423	163	11	,	,	PUNCT
admet-423	163	12	obesity	obesity	NOUN
admet-423	163	13	research	research	NOUN
admet-423	163	14	11	11	NUM
admet-423	163	15	(	(	PUNCT
admet-423	163	16	2003	2003	NUM
admet-423	163	17	)	)	PUNCT
admet-423	163	18	683	683	NUM
admet-423	163	19	-	-	SYM
admet-423	163	20	688	688	NUM
admet-423	163	21	;	;	PUNCT
admet-423	163	22	http://onlinelibrary.wiley.com/doi/10.1038/oby.2003.97/full	http://onlinelibrary.wiley.com/doi/10.1038/oby.2003.97/full	PROPN
admet-423	163	23	.	.	PUNCT
admet-423	164	1	[	[	X
admet-423	164	2	4	4	NUM
admet-423	164	3	]	]	X
admet-423	164	4	q.-x	q.-x	PROPN
admet-423	164	5	.	.	PUNCT
admet-423	164	6	wu	wu	PROPN
admet-423	164	7	,	,	PUNCT
admet-423	164	8	d.-q	d.-q	PROPN
admet-423	164	9	.	.	PUNCT
admet-423	165	1	lin	lin	PROPN
admet-423	165	2	,	,	PUNCT
admet-423	165	3	s.-j.yao	s.-j.yao	PROPN
admet-423	165	4	,	,	PUNCT
admet-423	165	5	marine	marine	ADJ
admet-423	165	6	drugs	drug	NOUN
admet-423	165	7	12	12	NUM
admet-423	165	8	(	(	PUNCT
admet-423	165	9	2014	2014	NUM
admet-423	165	10	)	)	PUNCT
admet-423	165	11	6236–6253	6236–6253	NOUN
admet-423	165	12	;	;	PUNCT
admet-423	165	13	http://www.mdpi.com/1660-3397/12/12/6236	http://www.mdpi.com/1660-3397/12/12/6236	PROPN
admet-423	165	14	.	.	PUNCT
admet-423	166	1	[	[	X
admet-423	166	2	5	5	NUM
admet-423	166	3	]	]	PUNCT
admet-423	166	4	v.	v.	CCONJ
admet-423	166	5	patrulea	patrulea	ADJ
admet-423	166	6	,	,	PUNCT
admet-423	166	7	v.	v.	ADP
admet-423	166	8	ostafe	ostafe	NOUN
admet-423	166	9	,	,	PUNCT
admet-423	166	10	g.	g.	PROPN
admet-423	166	11	borchard	borchard	PROPN
admet-423	166	12	,	,	PUNCT
admet-423	166	13	o.	o.	PROPN
admet-423	166	14	jordan	jordan	PROPN
admet-423	166	15	,	,	PUNCT
admet-423	166	16	european	european	PROPN
admet-423	166	17	journal	journal	PROPN
admet-423	166	18	of	of	ADP
admet-423	166	19	pharmaceutics	pharmaceutic	NOUN
admet-423	166	20	and	and	CCONJ
admet-423	166	21	biopharmaceutics	biopharmaceutic	NOUN
admet-423	166	22	97	97	NUM
admet-423	166	23	(	(	PUNCT
admet-423	166	24	2015	2015	NUM
admet-423	166	25	)	)	PUNCT
admet-423	167	1	417–426	417–426	NUM
admet-423	167	2	;	;	PUNCT
admet-423	167	3	http://linkinghub.elsevier.com/retrieve/pii/s0144861716300091	http://linkinghub.elsevier.com/retrieve/pii/s0144861716300091	ADJ
admet-423	167	4	.	.	PUNCT
admet-423	168	1	[	[	X
admet-423	168	2	6	6	NUM
admet-423	168	3	]	]	X
admet-423	168	4	i.wedmore	i.wedmore	NOUN
admet-423	168	5	,	,	PUNCT
admet-423	168	6	j.g	j.g	PROPN
admet-423	168	7	.	.	PROPN
admet-423	168	8	mcmanus	mcmanus	PROPN
admet-423	168	9	,	,	PUNCT
admet-423	168	10	a.e	a.e	PROPN
admet-423	168	11	.	.	PROPN
admet-423	168	12	pusateri	pusateri	PROPN
admet-423	168	13	,	,	PUNCT
admet-423	168	14	j.b	j.b	PROPN
admet-423	168	15	.	.	PROPN
admet-423	168	16	holcomb	holcomb	PROPN
admet-423	168	17	,	,	PUNCT
admet-423	168	18	journal	journal	NOUN
admet-423	168	19	of	of	ADP
admet-423	168	20	trauma	trauma	NOUN
admet-423	168	21	60	60	NUM
admet-423	168	22	(	(	PUNCT
admet-423	168	23	2006	2006	NUM
admet-423	168	24	)	)	PUNCT
admet-423	169	1	655–658	655–658	NUM
admet-423	169	2	;	;	PUNCT
admet-423	169	3	https://www.ncbi.nlm.nih.gov/pubmed/16531872	https://www.ncbi.nlm.nih.gov/pubmed/16531872	NUM
admet-423	169	4	.	.	PUNCT
admet-423	170	1	[	[	X
admet-423	170	2	7	7	X
admet-423	170	3	]	]	X
admet-423	170	4	l.	l.	PROPN
admet-423	170	5	illum	illum	PROPN
admet-423	170	6	,	,	PUNCT
admet-423	170	7	pharmaceutical	pharmaceutical	ADJ
admet-423	170	8	research	research	NOUN
admet-423	170	9	15	15	NUM
admet-423	170	10	(	(	PUNCT
admet-423	170	11	1998	1998	NUM
admet-423	170	12	)	)	PUNCT
admet-423	170	13	1326–1331	1326–1331	NUM
admet-423	170	14	;	;	PUNCT
admet-423	170	15	https://www.ncbi.nlm.nih.gov/pubmed/9755881	https://www.ncbi.nlm.nih.gov/pubmed/9755881	NUM
admet-423	170	16	.	.	PUNCT
admet-423	171	1	[	[	X
admet-423	171	2	8	8	NUM
admet-423	171	3	]	]	X
admet-423	171	4	f.	f.	PROPN
admet-423	171	5	seyfarth	seyfarth	PROPN
admet-423	171	6	,	,	PUNCT
admet-423	171	7	s.	s.	PROPN
admet-423	171	8	schliemann	schliemann	PROPN
admet-423	171	9	,	,	PUNCT
admet-423	171	10	p.	p.	NOUN
admet-423	171	11	elsner	elsner	NOUN
admet-423	171	12	,	,	PUNCT
admet-423	171	13	u.c	u.c	PROPN
admet-423	171	14	.	.	PROPN
admet-423	171	15	hipler	hipler	NOUN
admet-423	171	16	,	,	PUNCT
admet-423	171	17	international	international	ADJ
admet-423	171	18	journal	journal	NOUN
admet-423	171	19	of	of	ADP
admet-423	171	20	pharmaceutics	pharmaceutic	NOUN
admet-423	171	21	353	353	NUM
admet-423	171	22	(	(	PUNCT
admet-423	171	23	2008	2008	NUM
admet-423	171	24	)	)	PUNCT
admet-423	171	25	139–148	139–148	NUM
admet-423	171	26	;	;	PUNCT
admet-423	171	27	http://europepmc.org/abstract/med/18164151	http://europepmc.org/abstract/med/18164151	PROPN
admet-423	171	28	.	.	PUNCT
admet-423	172	1	[	[	X
admet-423	172	2	9	9	NUM
admet-423	172	3	]	]	PUNCT
admet-423	172	4	k.	k.	PROPN
admet-423	172	5	azuma	azuma	PROPN
admet-423	172	6	,	,	PUNCT
admet-423	172	7	r.	r.	PROPN
admet-423	172	8	izumi	izumi	PROPN
admet-423	172	9	,	,	PUNCT
admet-423	172	10	t.	t.	PROPN
admet-423	172	11	osaki	osaki	PROPN
admet-423	172	12	,	,	PUNCT
admet-423	172	13	s.	s.	PROPN
admet-423	172	14	ifuku	ifuku	PROPN
admet-423	172	15	,	,	PUNCT
admet-423	172	16	m.	m.	NOUN
admet-423	172	17	morimoto	morimoto	PROPN
admet-423	172	18	,	,	PUNCT
admet-423	172	19	h.	h.	PROPN
admet-423	172	20	saimoto	saimoto	PROPN
admet-423	172	21	,	,	PUNCT
admet-423	172	22	s.o	s.o	PROPN
admet-423	172	23	minami	minami	PROPN
admet-423	172	24	,	,	PUNCT
admet-423	172	25	y.	y.	PROPN
admet-423	172	26	okamoto	okamoto	PROPN
admet-423	172	27	,	,	PUNCT
admet-423	172	28	journal	journal	NOUN
admet-423	172	29	of	of	ADP
admet-423	172	30	functional	functional	ADJ
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admet-423	172	32	6	6	NUM
admet-423	172	33	(	(	PUNCT
admet-423	172	34	2015	2015	NUM
admet-423	172	35	)	)	PUNCT
admet-423	172	36	104	104	NUM
admet-423	172	37	-	-	SYM
admet-423	172	38	142	142	NUM
admet-423	172	39	;	;	PUNCT
admet-423	172	40	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4384104/.	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4384104/.	NOUN
admet-423	172	41	[	[	X
admet-423	172	42	10	10	NUM
admet-423	172	43	]	]	PUNCT
admet-423	172	44	m.	m.	NOUN
admet-423	172	45	sobol	sobol	NOUN
admet-423	172	46	,	,	PUNCT
admet-423	172	47	a.	a.	PROPN
admet-423	172	48	bartkowiak	bartkowiak	PROPN
admet-423	172	49	,	,	PUNCT
admet-423	172	50	b.	b.	PROPN
admet-423	172	51	de	de	X
admet-423	172	52	haan	haan	PROPN
admet-423	172	53	,	,	PUNCT
admet-423	172	54	p.	p.	PROPN
admet-423	172	55	de	de	X
admet-423	172	56	vos	vos	PROPN
admet-423	172	57	,	,	PUNCT
admet-423	172	58	journal	journal	NOUN
admet-423	172	59	of	of	ADP
admet-423	172	60	biomedical	biomedical	ADJ
admet-423	172	61	materials	material	NOUN
admet-423	172	62	research	research	NOUN
admet-423	172	63	part	part	NOUN
admet-423	172	64	a	a	DET
admet-423	172	65	101a	101a	PROPN
admet-423	172	66	(	(	PUNCT
admet-423	172	67	2013	2013	NUM
admet-423	172	68	)	)	PUNCT
admet-423	172	69	1907–1914	1907–1914	NUM
admet-423	172	70	;	;	PUNCT
admet-423	172	71	http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.34500/abstract	http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.34500/abstract	NOUN
admet-423	172	72	.	.	PUNCT
admet-423	173	1	[	[	X
admet-423	173	2	11	11	NUM
admet-423	173	3	]	]	PUNCT
admet-423	173	4	j.	j.	PROPN
admet-423	173	5	macossay	macossay	PROPN
admet-423	173	6	,	,	PUNCT
admet-423	173	7	lsu	lsu	VERB
admet-423	173	8	historical	historical	ADJ
admet-423	173	9	dissertations	dissertation	NOUN
admet-423	173	10	and	and	CCONJ
admet-423	173	11	theses	theses	X
admet-423	173	12	(	(	PUNCT
admet-423	173	13	1995	1995	NUM
admet-423	173	14	)	)	PUNCT
admet-423	173	15	6119	6119	NUM
admet-423	173	16	;	;	PUNCT
admet-423	173	17	http://digitalcommons.lsu.edu/gradschool_disstheses/6119	http://digitalcommons.lsu.edu/gradschool_disstheses/6119	PROPN
admet-423	173	18	.	.	PUNCT
admet-423	174	1	[	[	X
admet-423	174	2	12	12	NUM
admet-423	174	3	]	]	PUNCT
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admet-423	174	5	chemsketch	chemsketch	NOUN
admet-423	174	6	12.00	12.00	NUM
admet-423	174	7	and	and	CCONJ
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admet-423	174	11	;	;	PUNCT
admet-423	174	12	https://chemicalize.com	https://chemicalize.com	NUM
admet-423	174	13	;	;	PUNCT
admet-423	174	14	accessed	access	VERB
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admet-423	174	16	.	.	PUNCT
admet-423	175	1	[	[	X
admet-423	175	2	13	13	NUM
admet-423	175	3	]	]	X
admet-423	175	4	online	online	ADJ
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admet-423	175	6	translator	translator	NOUN
admet-423	175	7	and	and	CCONJ
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admet-423	175	9	file	file	NOUN
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admet-423	175	11	;	;	PUNCT
admet-423	175	12	https://cactus.nci.nih.gov/translate/	https://cactus.nci.nih.gov/translate/	CCONJ
admet-423	175	13	;	;	PUNCT
admet-423	175	14	accessed	access	VERB
admet-423	175	15	06.08.2017	06.08.2017	PUNCT
admet-423	175	16	and	and	CCONJ
admet-423	175	17	24.09.2017	24.09.2017	NUM
admet-423	175	18	.	.	PUNCT
admet-423	176	1	[	[	X
admet-423	176	2	14	14	NUM
admet-423	176	3	]	]	PUNCT
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admet-423	176	7	o.	o.	PROPN
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admet-423	176	11	zoete	zoete	NOUN
admet-423	176	12	,	,	PUNCT
admet-423	176	13	scientific	scientific	ADJ
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admet-423	176	15	7	7	NUM
admet-423	176	16	(	(	PUNCT
admet-423	176	17	2017	2017	NUM
admet-423	176	18	)	)	PUNCT
admet-423	176	19	42717	42717	NUM
admet-423	176	20	;	;	PUNCT
admet-423	176	21	https://www.nature.com/articles/srep42717?wt.feed_name=subjects_physical-sciences	https://www.nature.com/articles/srep42717?wt.feed_name=subjects_physical-sciences	PROPN
admet-423	176	22	.	.	PUNCT
admet-423	176	23	https://link.springer.com/chapter/10.1007%2f12_2011_137	https://link.springer.com/chapter/10.1007%2f12_2011_137	PROPN
admet-423	177	1	http://www.mdpi.com/1660-3397/13/8/5156	http://www.mdpi.com/1660-3397/13/8/5156	PROPN
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admet-423	177	5	https://www.ncbi.nlm.nih.gov/pubmed/16531872	https://www.ncbi.nlm.nih.gov/pubmed/16531872	NOUN
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admet-423	177	7	http://europepmc.org/abstract/med/18164151	http://europepmc.org/abstract/med/18164151	PROPN
admet-423	177	8	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4384104/	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4384104/	PROPN
admet-423	177	9	http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.34500/abstract	http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.34500/abstract	PROPN
admet-423	177	10	http://digitalcommons.lsu.edu/gradschool_disstheses/6119	http://digitalcommons.lsu.edu/gradschool_disstheses/6119	PRON
admet-423	177	11	https://chemicalize.com/	https://chemicalize.com/	PROPN
admet-423	177	12	https://cactus.nci.nih.gov/translate/	https://cactus.nci.nih.gov/translate/	ADJ
admet-423	177	13	https://www.nature.com/articles/srep42717?wt.feed_name=subjects_physical-sciences	https://www.nature.com/articles/srep42717?wt.feed_name=subjects_physical-science	NOUN
admet-423	177	14	isvoran	isvoran	ADJ
admet-423	177	15	,	,	PUNCT
admet-423	177	16	ciorsac	ciorsac	NOUN
admet-423	177	17	,	,	PUNCT
admet-423	177	18	ostafe	ostafe	NOUN
admet-423	177	19	admet	admet	PROPN
admet-423	177	20	&	&	CCONJ
admet-423	177	21	dmpk	dmpk	PROPN
admet-423	177	22	5(3	5(3	NUM
admet-423	177	23	)	)	PUNCT
admet-423	177	24	(	(	PUNCT
admet-423	177	25	2017	2017	NUM
admet-423	177	26	)	)	PUNCT
admet-423	177	27	192	192	NUM
admet-423	177	28	-	-	SYM
admet-423	177	29	200	200	NUM
admet-423	177	30	200	200	NUM
admet-423	177	31	[	[	SYM
admet-423	177	32	15	15	NUM
admet-423	177	33	]	]	X
admet-423	177	34	d.	d.	PROPN
admet-423	177	35	lagorce	lagorce	PROPN
admet-423	177	36	,	,	PUNCT
admet-423	177	37	o.	o.	PROPN
admet-423	177	38	sperandio	sperandio	PROPN
admet-423	177	39	,	,	PUNCT
admet-423	177	40	j.b	j.b	PROPN
admet-423	177	41	.	.	PROPN
admet-423	177	42	baell	baell	PROPN
admet-423	177	43	,	,	PUNCT
admet-423	177	44	m.a	m.a	PROPN
admet-423	177	45	.	.	PROPN
admet-423	177	46	miteva	miteva	PROPN
admet-423	177	47	,	,	PUNCT
admet-423	178	1	b.o	b.o	PROPN
admet-423	178	2	.	.	PROPN
admet-423	178	3	villoutreix	villoutreix	PROPN
admet-423	178	4	,	,	PUNCT
admet-423	178	5	nucleic	nucleic	ADJ
admet-423	178	6	acids	acid	NOUN
admet-423	178	7	research	research	NOUN
admet-423	178	8	43	43	NUM
admet-423	178	9	(	(	PUNCT
admet-423	178	10	2015	2015	NUM
admet-423	178	11	)	)	PUNCT
admet-423	179	1	w200	w200	PROPN
admet-423	179	2	-	-	PUNCT
admet-423	179	3	207	207	NUM
admet-423	179	4	;	;	PUNCT
admet-423	179	5	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4489254/.	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4489254/.	NOUN
admet-423	180	1	[	[	X
admet-423	180	2	16	16	NUM
admet-423	180	3	]	]	X
admet-423	180	4	d.	d.	PROPN
admet-423	180	5	lagorce	lagorce	PROPN
admet-423	180	6	,	,	PUNCT
admet-423	180	7	l.	l.	PROPN
admet-423	180	8	bouslama	bouslama	PROPN
admet-423	180	9	,	,	PUNCT
admet-423	180	10	j.	j.	PROPN
admet-423	180	11	becot	becot	PROPN
admet-423	180	12	,	,	PUNCT
admet-423	180	13	m.a	m.a	PROPN
admet-423	180	14	.	.	PROPN
admet-423	180	15	miteva	miteva	PROPN
admet-423	180	16	,	,	PUNCT
admet-423	181	1	b.o	b.o	PROPN
admet-423	181	2	.	.	PROPN
admet-423	181	3	villoutreix	villoutreix	PROPN
admet-423	181	4	,	,	PUNCT
admet-423	181	5	bioinformatics	bioinformatic	NOUN
admet-423	181	6	(	(	PUNCT
admet-423	181	7	2017	2017	NUM
admet-423	181	8	)	)	PUNCT
admet-423	181	9	accepted	accept	VERB
admet-423	181	10	manuscript	manuscript	NOUN
admet-423	181	11	;	;	PUNCT
admet-423	181	12	https://doi.org/10.1093/bioinformatics/btx491	https://doi.org/10.1093/bioinformatics/btx491	ADJ
admet-423	181	13	.	.	PUNCT
admet-423	182	1	[	[	X
admet-423	182	2	17	17	NUM
admet-423	182	3	]	]	X
admet-423	182	4	a.v	a.v	PROPN
admet-423	182	5	.	.	PROPN
admet-423	182	6	stepanchikova	stepanchikova	PROPN
admet-423	182	7	,	,	PUNCT
admet-423	182	8	a.a	a.a	PROPN
admet-423	182	9	.	.	PROPN
admet-423	182	10	lagunin	lagunin	PROPN
admet-423	182	11	,	,	PUNCT
admet-423	182	12	d.a	d.a	PROPN
admet-423	182	13	.	.	PROPN
admet-423	182	14	filimonov	filimonov	PROPN
admet-423	182	15	,	,	PUNCT
admet-423	182	16	v.v	v.v	PROPN
admet-423	182	17	.	.	PROPN
admet-423	182	18	poroikov	poroikov	NOUN
admet-423	182	19	,	,	PUNCT
admet-423	182	20	current	current	ADJ
admet-423	182	21	medicinal	medicinal	ADJ
admet-423	182	22	chemistry	chemistry	NOUN
admet-423	182	23	10	10	NUM
admet-423	182	24	(	(	PUNCT
admet-423	182	25	2003	2003	NUM
admet-423	182	26	)	)	PUNCT
admet-423	182	27	225	225	NUM
admet-423	182	28	-	-	SYM
admet-423	182	29	233	233	NUM
admet-423	182	30	;	;	PUNCT
admet-423	182	31	https://pdfs.semanticscholar.org/33af/3c27932acc01595715a322d2795ac45ae2cd.pdf	https://pdfs.semanticscholar.org/33af/3c27932acc01595715a322d2795ac45ae2cd.pdf	PROPN
admet-423	182	32	.	.	PUNCT
admet-423	183	1	[	[	X
admet-423	183	2	18	18	NUM
admet-423	183	3	]	]	PUNCT
admet-423	183	4	l.	l.	PROPN
admet-423	183	5	zhang	zhang	PROPN
admet-423	183	6	,	,	PUNCT
admet-423	183	7	h.	h.	PROPN
admet-423	183	8	ai	ai	PROPN
admet-423	183	9	,	,	PUNCT
admet-423	183	10	w.	w.	PROPN
admet-423	183	11	chen	chen	PROPN
admet-423	183	12	,	,	PUNCT
admet-423	183	13	z.yin	z.yin	PROPN
admet-423	183	14	,	,	PUNCT
admet-423	183	15	h.	h.	PROPN
admet-423	183	16	hu	hu	PROPN
admet-423	183	17	,	,	PUNCT
admet-423	183	18	j.	j.	PROPN
admet-423	183	19	zhu	zhu	PROPN
admet-423	183	20	,	,	PUNCT
admet-423	183	21	j.	j.	PROPN
admet-423	183	22	zhao	zhao	PROPN
admet-423	183	23	,	,	PUNCT
admet-423	183	24	q.	q.	PROPN
admet-423	183	25	zhao	zhao	PROPN
admet-423	183	26	,	,	PUNCT
admet-423	183	27	h.	h.	PROPN
admet-423	183	28	liu	liu	PROPN
admet-423	183	29	,	,	PUNCT
admet-423	183	30	scientific	scientific	ADJ
admet-423	183	31	reports	report	NOUN
admet-423	183	32	7	7	NUM
admet-423	183	33	(	(	PUNCT
admet-423	183	34	2017	2017	NUM
admet-423	183	35	)	)	PUNCT
admet-423	183	36	2118	2118	NUM
admet-423	183	37	;	;	PUNCT
admet-423	183	38	https://www.nature.com/articles/s41598-017-02365-0	https://www.nature.com/articles/s41598-017-02365-0	X
admet-423	183	39	.	.	PUNCT
admet-423	184	1	[	[	X
admet-423	184	2	19	19	NUM
admet-423	184	3	]	]	X
admet-423	184	4	r.c	r.c	PROPN
admet-423	184	5	.	.	PROPN
admet-423	184	6	braga	braga	PROPN
admet-423	184	7	;	;	PUNCT
admet-423	184	8	v.m	v.m	PROPN
admet-423	184	9	.	.	PROPN
admet-423	184	10	alves	alves	PROPN
admet-423	184	11	,	,	PUNCT
admet-423	184	12	m.f.b	m.f.b	PROPN
admet-423	184	13	.	.	PROPN
admet-423	184	14	silva	silva	PROPN
admet-423	184	15	;	;	PUNCT
admet-423	184	16	e.	e.	PROPN
admet-423	184	17	muratov	muratov	PROPN
admet-423	184	18	,	,	PUNCT
admet-423	184	19	d.	d.	PROPN
admet-423	184	20	fourches	fourches	PROPN
admet-423	184	21	,	,	PUNCT
admet-423	184	22	l.m	l.m	PROPN
admet-423	184	23	.	.	PROPN
admet-423	184	24	liao	liao	PROPN
admet-423	184	25	,	,	PUNCT
admet-423	184	26	a.	a.	NOUN
admet-423	184	27	tropsha	tropsha	PROPN
admet-423	184	28	,	,	PUNCT
admet-423	184	29	c.h	c.h	PROPN
admet-423	184	30	.	.	PROPN
admet-423	184	31	andrade	andrade	PROPN
admet-423	184	32	,	,	PUNCT
admet-423	184	33	molecular	molecular	ADJ
admet-423	184	34	informatics	informatic	NOUN
admet-423	184	35	34	34	NUM
admet-423	184	36	(	(	PUNCT
admet-423	184	37	2015	2015	NUM
admet-423	184	38	)	)	PUNCT
admet-423	184	39	698	698	NUM
admet-423	184	40	-	-	SYM
admet-423	184	41	701	701	NUM
admet-423	184	42	;	;	PUNCT
admet-423	184	43	http://onlinelibrary.wiley.com/doi/10.1002/minf.201500040/suppinfo	http://onlinelibrary.wiley.com/doi/10.1002/minf.201500040/suppinfo	X
admet-423	184	44	.	.	PUNCT
admet-423	185	1	[	[	X
admet-423	185	2	20	20	NUM
admet-423	185	3	]	]	PUNCT
admet-423	185	4	k.	k.	PROPN
admet-423	185	5	olšek	olšek	PROPN
admet-423	185	6	,	,	PUNCT
admet-423	185	7	j.	j.	PROPN
admet-423	185	8	mavri	mavri	PROPN
admet-423	185	9	,	,	PUNCT
admet-423	186	1	m	m	PROPN
admet-423	186	2	sollner	sollner	NOUN
admet-423	186	3	dolenc	dolenc	PROPN
admet-423	186	4	,	,	PUNCT
admet-423	186	5	s.	s.	PROPN
admet-423	186	6	gobec	gobec	PROPN
admet-423	186	7	,	,	PUNCT
admet-423	186	8	s.	s.	PROPN
admet-423	186	9	turk	turk	PROPN
admet-423	186	10	,	,	PUNCT
admet-423	186	11	journal	journal	NOUN
admet-423	186	12	of	of	ADP
admet-423	186	13	chemical	chemical	ADJ
admet-423	186	14	information	information	NOUN
admet-423	186	15	and	and	CCONJ
admet-423	186	16	modeling	model	VERB
admet-423	186	17	54	54	NUM
admet-423	186	18	(	(	PUNCT
admet-423	186	19	2014	2014	NUM
admet-423	186	20	)	)	PUNCT
admet-423	186	21	1254	1254	NUM
admet-423	186	22	-	-	SYM
admet-423	186	23	1267	1267	NUM
admet-423	186	24	;	;	PUNCT
admet-423	186	25	http://pubs.acs.org/doi/abs/10.1021/ci400649p	http://pubs.acs.org/doi/abs/10.1021/ci400649p	NOUN
admet-423	186	26	.	.	PUNCT
admet-423	187	1	[	[	X
admet-423	187	2	21	21	NUM
admet-423	187	3	]	]	X
admet-423	187	4	r.o	r.o	PROPN
admet-423	187	5	.	.	PROPN
admet-423	187	6	potts	potts	PROPN
admet-423	187	7	,	,	PUNCT
admet-423	187	8	r.h	r.h	PROPN
admet-423	187	9	.	.	PROPN
admet-423	187	10	guy	guy	NOUN
admet-423	187	11	,	,	PUNCT
admet-423	187	12	pharmaceutical	pharmaceutical	ADJ
admet-423	187	13	research	research	NOUN
admet-423	187	14	5	5	NUM
admet-423	187	15	(	(	PUNCT
admet-423	187	16	1992	1992	NUM
admet-423	187	17	)	)	PUNCT
admet-423	187	18	663	663	NUM
admet-423	187	19	-	-	SYM
admet-423	187	20	669	669	NUM
admet-423	187	21	.	.	PUNCT
admet-423	188	1	[	[	X
admet-423	188	2	22	22	NUM
admet-423	188	3	]	]	PUNCT
admet-423	188	4	l.	l.	PROPN
admet-423	188	5	s.	s.	PROPN
admet-423	188	6	gold	gold	PROPN
admet-423	188	7	,	,	PUNCT
admet-423	188	8	t.	t.	PROPN
admet-423	188	9	h.	h.	PROPN
admet-423	188	10	slone	slone	PROPN
admet-423	188	11	,	,	PUNCT
admet-423	188	12	n.	n.	PROPN
admet-423	188	13	b.	b.	PROPN
admet-423	188	14	manley	manley	PROPN
admet-423	188	15	,	,	PUNCT
admet-423	188	16	g.	g.	PROPN
admet-423	188	17	b.	b.	PROPN
admet-423	188	18	garfinkel	garfinkel	PROPN
admet-423	188	19	,	,	PUNCT
admet-423	188	20	e.	e.	PROPN
admet-423	188	21	s.	s.	PROPN
admet-423	188	22	hudes	hude	VERB
admet-423	188	23	,	,	PUNCT
admet-423	188	24	l.	l.	PROPN
admet-423	188	25	rohrbach	rohrbach	PROPN
admet-423	188	26	,	,	PUNCT
admet-423	188	27	b.	b.	PROPN
admet-423	188	28	n.	n.	PROPN
admet-423	188	29	ames	ames	PROPN
admet-423	188	30	,	,	PUNCT
admet-423	188	31	environmental	environmental	ADJ
admet-423	188	32	health	health	NOUN
admet-423	188	33	perspectives	perspective	NOUN
admet-423	188	34	96	96	NUM
admet-423	188	35	(	(	PUNCT
admet-423	188	36	1991	1991	NUM
admet-423	188	37	)	)	PUNCT
admet-423	188	38	11	11	NUM
admet-423	188	39	-	-	SYM
admet-423	188	40	15	15	NUM
admet-423	188	41	;	;	PUNCT
admet-423	188	42	http://pubmedcentralcanada.ca/pmcc/articles/pmc1568255/pdf/envhper00416-0018.pdf	http://pubmedcentralcanada.ca/pmcc/articles/pmc1568255/pdf/envhper00416-0018.pdf	NOUN
admet-423	188	43	.	.	PUNCT
admet-423	189	1	[	[	X
admet-423	189	2	23	23	NUM
admet-423	189	3	]	]	X
admet-423	189	4	r.	r.	PROPN
admet-423	189	5	benigni	benigni	PROPN
admet-423	189	6	,	,	PUNCT
admet-423	189	7	c.	c.	PROPN
admet-423	189	8	bossa	bossa	PROPN
admet-423	189	9	,	,	PUNCT
admet-423	189	10	a.	a.	PROPN
admet-423	189	11	m.	m.	PROPN
admet-423	189	12	richard	richard	PROPN
admet-423	189	13	,	,	PUNCT
admet-423	189	14	c.	c.	PROPN
admet-423	189	15	yang	yang	PROPN
admet-423	189	16	,	,	PUNCT
admet-423	189	17	annali	annali	PROPN
admet-423	189	18	dell'istituto	dell'istituto	PROPN
admet-423	189	19	superiore	superiore	PROPN
admet-423	189	20	di	di	PROPN
admet-423	189	21	sanita	sanita	PROPN
admet-423	189	22	44	44	NUM
admet-423	189	23	(	(	PUNCT
admet-423	189	24	2008	2008	NUM
admet-423	189	25	)	)	PUNCT
admet-423	189	26	48–56	48–56	NUM
admet-423	189	27	;	;	PUNCT
admet-423	189	28	http://www.iss.it/publ/anna/2008/1/44148.pdf	http://www.iss.it/publ/anna/2008/1/44148.pdf	NOUN
admet-423	189	29	.	.	PUNCT
admet-423	190	1	[	[	X
admet-423	190	2	24	24	NUM
admet-423	190	3	]	]	X
admet-423	190	4	a.p	a.p	PROPN
admet-423	190	5	.	.	PROPN
admet-423	190	6	bento	bento	PROPN
admet-423	190	7	,	,	PUNCT
admet-423	190	8	a.	a.	NOUN
admet-423	190	9	gaulton	gaulton	PROPN
admet-423	190	10	,	,	PUNCT
admet-423	190	11	a.	a.	PROPN
admet-423	190	12	hersey	hersey	PROPN
admet-423	190	13	,	,	PUNCT
admet-423	190	14	l.j	l.j	PROPN
admet-423	190	15	.	.	PROPN
admet-423	190	16	bellis	bellis	PROPN
admet-423	190	17	,	,	PUNCT
admet-423	190	18	j.	j.	PROPN
admet-423	190	19	chambers	chambers	PROPN
admet-423	190	20	,	,	PUNCT
admet-423	190	21	m.	m.	NOUN
admet-423	190	22	davies	davy	NOUN
admet-423	190	23	,	,	PUNCT
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admet-423	190	27	,	,	PUNCT
admet-423	190	28	y.	y.	PROPN
admet-423	190	29	light	light	PROPN
admet-423	190	30	,	,	PUNCT
admet-423	190	31	l.	l.	PROPN
admet-423	190	32	mak	mak	PROPN
admet-423	190	33	,	,	PUNCT
admet-423	190	34	s.	s.	PROPN
admet-423	190	35	mcglinchey	mcglinchey	PROPN
admet-423	190	36	,	,	PUNCT
admet-423	190	37	m.	m.	NOUN
admet-423	190	38	nowotka	nowotka	PROPN
admet-423	190	39	,	,	PUNCT
admet-423	190	40	g.	g.	PROPN
admet-423	190	41	papadatos	papadatos	PROPN
admet-423	190	42	,	,	PUNCT
admet-423	190	43	r.	r.	PROPN
admet-423	190	44	santos	santos	PROPN
admet-423	190	45	,	,	PUNCT
admet-423	190	46	j.p	j.p	PROPN
admet-423	190	47	.	.	PROPN
admet-423	190	48	overington	overington	PROPN
admet-423	190	49	,	,	PUNCT
admet-423	190	50	nucleic	nucleic	ADJ
admet-423	190	51	acids	acid	NOUN
admet-423	190	52	research	research	NOUN
admet-423	190	53	42	42	NUM
admet-423	190	54	(	(	PUNCT
admet-423	190	55	2014	2014	NUM
admet-423	190	56	)	)	PUNCT
admet-423	190	57	1083	1083	NUM
admet-423	190	58	-	-	SYM
admet-423	190	59	1090	1090	NUM
admet-423	190	60	;	;	PUNCT
admet-423	190	61	https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkt1031	https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkt1031	NOUN
admet-423	190	62	.	.	PUNCT
admet-423	191	1	[	[	X
admet-423	191	2	25	25	NUM
admet-423	191	3	]	]	X
admet-423	191	4	o.	o.	PROPN
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admet-423	191	6	,	,	PUNCT
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admet-423	191	10	,	,	PUNCT
admet-423	191	11	journal	journal	NOUN
admet-423	191	12	of	of	ADP
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admet-423	191	15	31	31	NUM
admet-423	191	16	(	(	PUNCT
admet-423	191	17	2010	2010	NUM
admet-423	191	18	)	)	PUNCT
admet-423	191	19	455	455	NUM
admet-423	191	20	-	-	SYM
admet-423	191	21	461	461	NUM
admet-423	191	22	;	;	PUNCT
admet-423	191	23	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3041641/.	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3041641/.	PROPN
admet-423	192	1	[	[	X
admet-423	192	2	26	26	NUM
admet-423	192	3	]	]	X
admet-423	192	4	h.m	h.m	PROPN
admet-423	192	5	.	.	PROPN
admet-423	192	6	berman	berman	PROPN
admet-423	192	7	,	,	PUNCT
admet-423	192	8	j.	j.	PROPN
admet-423	192	9	westbrook	westbrook	PROPN
admet-423	192	10	,	,	PUNCT
admet-423	192	11	z.	z.	PROPN
admet-423	192	12	feng	feng	PROPN
admet-423	192	13	,	,	PUNCT
admet-423	192	14	g.	g.	PROPN
admet-423	192	15	gilliland	gilliland	PROPN
admet-423	192	16	,	,	PUNCT
admet-423	192	17	t.n	t.n	PROPN
admet-423	192	18	.	.	PROPN
admet-423	192	19	bhat	bhat	PROPN
admet-423	192	20	,	,	PUNCT
admet-423	192	21	h.	h.	PROPN
admet-423	192	22	weissig	weissig	PROPN
admet-423	192	23	,	,	PUNCT
admet-423	192	24	i.n	i.n	PROPN
admet-423	192	25	.	.	PROPN
admet-423	192	26	shindyalov	shindyalov	PROPN
admet-423	192	27	,	,	PUNCT
admet-423	192	28	p.e	p.e	PROPN
admet-423	192	29	.	.	PROPN
admet-423	192	30	bourne	bourne	PROPN
admet-423	192	31	,	,	PUNCT
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admet-423	192	33	acids	acid	NOUN
admet-423	192	34	research	research	NOUN
admet-423	192	35	28	28	NUM
admet-423	192	36	(	(	PUNCT
admet-423	192	37	2000	2000	NUM
admet-423	192	38	)	)	PUNCT
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admet-423	192	40	-	-	SYM
admet-423	192	41	242	242	NUM
admet-423	192	42	;	;	PUNCT
admet-423	192	43	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc102472/.	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc102472/.	NOUN
admet-423	193	1	[	[	X
admet-423	193	2	27	27	NUM
admet-423	193	3	]	]	PUNCT
admet-423	193	4	j.	j.	PROPN
admet-423	193	5	a.	a.	PROPN
admet-423	193	6	shayman	shayman	PROPN
admet-423	193	7	,	,	PUNCT
admet-423	193	8	a.	a.	PROPN
admet-423	193	9	abe	abe	PROPN
admet-423	193	10	,	,	PUNCT
admet-423	193	11	biochimica	biochimica	PROPN
admet-423	193	12	and	and	CCONJ
admet-423	193	13	biophysica	biophysica	PROPN
admet-423	193	14	acta	acta	PROPN
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admet-423	193	16	(	(	PUNCT
admet-423	193	17	2013	2013	NUM
admet-423	193	18	)	)	PUNCT
admet-423	194	1	602–611	602–611	NUM
admet-423	194	2	;	;	PUNCT
admet-423	194	3	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3528828/.	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3528828/.	NOUN
admet-423	195	1	[	[	X
admet-423	195	2	28	28	NUM
admet-423	195	3	]	]	X
admet-423	195	4	e.m	e.m	PROPN
admet-423	195	5	.	.	PROPN
admet-423	195	6	costa	costa	PROPN
admet-423	195	7	,	,	PUNCT
admet-423	195	8	s.	s.	PROPN
admet-423	195	9	silva	silva	PROPN
admet-423	195	10	,	,	PUNCT
admet-423	195	11	m.r	m.r	PROPN
admet-423	195	12	.	.	PROPN
admet-423	195	13	costa	costa	PROPN
admet-423	195	14	,	,	PUNCT
admet-423	195	15	m.	m.	PROPN
admet-423	195	16	pereira	pereira	PROPN
admet-423	195	17	,	,	PUNCT
admet-423	195	18	d.a	d.a	PROPN
admet-423	195	19	.	.	PROPN
admet-423	195	20	campos	campos	PROPN
admet-423	195	21	,	,	PUNCT
admet-423	195	22	j.	j.	PROPN
admet-423	195	23	odila	odila	PROPN
admet-423	195	24	,	,	PUNCT
admet-423	195	25	a.r	a.r	PROPN
admet-423	195	26	.	.	PROPN
admet-423	195	27	madureira	madureira	PROPN
admet-423	195	28	,	,	PUNCT
admet-423	195	29	a.	a.	PROPN
admet-423	195	30	cardellecobas	cardellecobas	PROPN
admet-423	195	31	,	,	PUNCT
admet-423	195	32	f.k	f.k	PROPN
admet-423	195	33	.	.	PROPN
admet-423	195	34	tavaria	tavaria	PROPN
admet-423	195	35	,	,	PUNCT
admet-423	195	36	,	,	PUNCT
admet-423	195	37	a.s	a.s	PROPN
admet-423	195	38	.	.	PROPN
admet-423	195	39	rodrigues	rodrigues	PROPN
admet-423	195	40	,	,	PUNCT
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admet-423	195	42	polymers	polymer	NOUN
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admet-423	195	45	2014	2014	NUM
admet-423	195	46	)	)	PUNCT
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admet-423	195	48	;	;	PUNCT
admet-423	195	49	http://www.sciencedirect.com/science/article/pii/s0144861714004032?via%3dihub	http://www.sciencedirect.com/science/article/pii/s0144861714004032?via%3dihub	X
admet-423	195	50	.	.	PUNCT
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admet-423	196	2	29	29	NUM
admet-423	196	3	]	]	X
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admet-423	196	5	.	.	PROPN
admet-423	196	6	chen	chen	PROPN
admet-423	196	7	,	,	PUNCT
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admet-423	196	9	.	.	PROPN
admet-423	196	10	chung	chung	PROPN
admet-423	196	11	,	,	PUNCT
admet-423	196	12	journal	journal	NOUN
admet-423	196	13	of	of	ADP
admet-423	196	14	applied	apply	VERB
admet-423	196	15	oral	oral	ADJ
admet-423	196	16	science	science	NOUN
admet-423	196	17	20	20	NUM
admet-423	196	18	(	(	PUNCT
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admet-423	196	20	)	)	PUNCT
admet-423	196	21	620–627	620–627	NUM
admet-423	196	22	;	;	PUNCT
admet-423	196	23	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3881855/.	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3881855/.	PROPN
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admet-423	196	29	,	,	PUNCT
admet-423	196	30	h.	h.	PROPN
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admet-423	196	32	,	,	PUNCT
admet-423	196	33	x.	x.	PROPN
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admet-423	196	35	,	,	PUNCT
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admet-423	196	38	,	,	PUNCT
admet-423	196	39	p.	p.	PROPN
admet-423	196	40	li	li	PROPN
admet-423	196	41	,	,	PUNCT
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admet-423	196	43	5	5	NUM
admet-423	196	44	(	(	PUNCT
admet-423	196	45	2017	2017	NUM
admet-423	196	46	)	)	PUNCT
admet-423	196	47	e3279	e3279	NOUN
admet-423	196	48	;	;	PUNCT
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admet-423	196	50	.	.	PUNCT
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admet-423	197	8	thanou	thanou	PROPN
admet-423	197	9	,	,	PUNCT
admet-423	197	10	advanced	advanced	ADJ
admet-423	197	11	drug	drug	NOUN
admet-423	197	12	delivery	delivery	NOUN
admet-423	197	13	reviews	review	NOUN
admet-423	197	14	,	,	PUNCT
admet-423	197	15	62	62	NUM
admet-423	197	16	(	(	PUNCT
admet-423	197	17	2010	2010	NUM
admet-423	197	18	)	)	PUNCT
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admet-423	197	20	;	;	PUNCT
admet-423	197	21	http://www.sciencedirect.com/science/article/pii/s0169409x0900283x?via%3dihub	http://www.sciencedirect.com/science/article/pii/s0169409x0900283x?via%3dihub	PROPN
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admet-423	198	6	;	;	PUNCT
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admet-423	198	8	iapc	iapc	PROPN
admet-423	198	9	,	,	PUNCT
admet-423	198	10	zagreb	zagreb	PROPN
admet-423	198	11	,	,	PUNCT
admet-423	198	12	croatia	croatia	PROPN
admet-423	198	13	.	.	PUNCT
admet-423	199	1	this	this	DET
admet-423	199	2	article	article	NOUN
admet-423	199	3	is	be	AUX
admet-423	199	4	an	an	DET
admet-423	199	5	open	open	ADJ
admet-423	199	6	-	-	PUNCT
admet-423	199	7	access	access	NOUN
admet-423	199	8	article	article	NOUN
admet-423	199	9	distributed	distribute	VERB
admet-423	199	10	under	under	ADP
admet-423	199	11	the	the	DET
admet-423	199	12	terms	term	NOUN
admet-423	199	13	and	and	CCONJ
admet-423	199	14	conditions	condition	NOUN
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admet-423	199	17	creative	creative	ADJ
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admet-423	199	20	license	license	NOUN
admet-423	199	21	(	(	PUNCT
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admet-423	199	27	https://www.nature.com/articles/s41598-017-02365-0	https://www.nature.com/articles/s41598-017-02365-0	AUX
admet-423	199	28	http://onlinelibrary.wiley.com/doi/10.1002/minf.201500040/suppinfo	http://onlinelibrary.wiley.com/doi/10.1002/minf.201500040/suppinfo	VERB
admet-423	199	29	http://pubs.acs.org/doi/abs/10.1021/ci400649p	http://pubs.acs.org/doi/abs/10.1021/ci400649p	ADJ
admet-423	199	30	http://pubmedcentralcanada.ca/pmcc/articles/pmc1568255/pdf/envhper00416-0018.pdf	http://pubmedcentralcanada.ca/pmcc/articles/pmc1568255/pdf/envhper00416-0018.pdf	NOUN
admet-423	199	31	http://www.iss.it/publ/anna/2008/1/44148.pdf	http://www.iss.it/publ/anna/2008/1/44148.pdf	NOUN
admet-423	199	32	https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkt1031	https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkt1031	NOUN
admet-423	199	33	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3041641/	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3041641/	PROPN
admet-423	199	34	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc102472/	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc102472/	PROPN
admet-423	199	35	http://www.sciencedirect.com/science/article/pii/s0144861714004032?via%3dihub	http://www.sciencedirect.com/science/article/pii/s0144861714004032?via%3dihub	PROPN
admet-423	199	36	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3881855/	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3881855/	PROPN
admet-423	199	37	https://dx.doi.org/10.7717/peerj.3279	https://dx.doi.org/10.7717/peerj.3279	VERB
admet-423	199	38	http://www.sciencedirect.com/science/article/pii/s0169409x0900283x?via%3dihub	http://www.sciencedirect.com/science/article/pii/s0169409x0900283x?via%3dihub	PROPN
admet-423	199	39	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN