id	sid	tid	token	lemma	pos
admet-425	1	1	in	in	ADP
admet-425	1	2	vitro	vitro	X
admet-425	1	3	dissolution	dissolution	NOUN
admet-425	1	4	/	/	SYM
admet-425	1	5	release	release	NOUN
admet-425	1	6	methods	method	NOUN
admet-425	1	7	for	for	ADP
admet-425	1	8	mucosal	mucosal	NOUN
admet-425	1	9	delivery	delivery	NOUN
admet-425	1	10	systems	system	NOUN
admet-425	1	11	doi	doi	NOUN
admet-425	1	12	:	:	PUNCT
admet-425	1	13	10.5599	10.5599	NUM
admet-425	1	14	/	/	SYM
admet-425	1	15	admet.5.3.425	admet.5.3.425	X
admet-425	1	16	173	173	NUM
admet-425	1	17	admet	admet	X
admet-425	1	18	&	&	CCONJ
admet-425	1	19	dmpk	dmpk	PROPN
admet-425	1	20	5(3	5(3	NUM
admet-425	1	21	)	)	PUNCT
admet-425	1	22	(	(	PUNCT
admet-425	1	23	2017	2017	NUM
admet-425	1	24	)	)	PUNCT
admet-425	1	25	173	173	NUM
admet-425	1	26	-	-	SYM
admet-425	1	27	182	182	NUM
admet-425	1	28	;	;	PUNCT
admet-425	1	29	doi	doi	NOUN
admet-425	1	30	:	:	PUNCT
admet-425	1	31	http://dx.doi.org/10.5599/admet.5.3.425	http://dx.doi.org/10.5599/admet.5.3.425	X
admet-425	1	32	open	open	ADJ
admet-425	1	33	access	access	NOUN
admet-425	1	34	:	:	PUNCT
admet-425	1	35	issn	issn	PROPN
admet-425	1	36	:	:	PUNCT
admet-425	1	37	1848	1848	NUM
admet-425	1	38	-	-	SYM
admet-425	1	39	7718	7718	NUM
admet-425	1	40	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-425	1	41	review	review	NOUN
admet-425	1	42	in	in	ADP
admet-425	1	43	vitro	vitro	X
admet-425	1	44	dissolution	dissolution	NOUN
admet-425	1	45	/	/	SYM
admet-425	1	46	release	release	NOUN
admet-425	1	47	methods	method	NOUN
admet-425	1	48	for	for	ADP
admet-425	1	49	mucosal	mucosal	NOUN
admet-425	1	50	delivery	delivery	NOUN
admet-425	1	51	systems	systems	PROPN
admet-425	1	52	mario	mario	PROPN
admet-425	1	53	jug*1	jug*1	PROPN
admet-425	1	54	,	,	PUNCT
admet-425	1	55	anita	anita	PROPN
admet-425	1	56	hafner1	hafner1	PROPN
admet-425	1	57	,	,	PUNCT
admet-425	1	58	jasmina	jasmina	PROPN
admet-425	1	59	lovrić1	lovrić1	PROPN
admet-425	1	60	,	,	PUNCT
admet-425	1	61	maja	maja	PROPN
admet-425	1	62	lusina	lusina	PROPN
admet-425	1	63	kregar2	kregar2	PROPN
admet-425	1	64	,	,	PUNCT
admet-425	1	65	ivan	ivan	PROPN
admet-425	1	66	pepić1	pepić1	PROPN
admet-425	1	67	,	,	PUNCT
admet-425	1	68	željka	željka	PROPN
admet-425	1	69	vanić1	vanić1	PROPN
admet-425	1	70	,	,	PUNCT
admet-425	1	71	biserka	biserka	PROPN
admet-425	1	72	cetina	cetina	NOUN
admet-425	1	73	-	-	PUNCT
admet-425	1	74	čižmek2	čižmek2	PROPN
admet-425	1	75	,	,	PUNCT
admet-425	1	76	jelena	jelena	PROPN
admet-425	1	77	filipović	filipović	PROPN
admet-425	1	78	-	-	PUNCT
admet-425	1	79	grčić1	grčić1	PROPN
admet-425	1	80	1	1	NUM
admet-425	1	81	university	university	NOUN
admet-425	1	82	of	of	ADP
admet-425	1	83	zagreb	zagreb	PROPN
admet-425	1	84	,	,	PUNCT
admet-425	1	85	faculty	faculty	NOUN
admet-425	1	86	of	of	ADP
admet-425	1	87	pharmacy	pharmacy	NOUN
admet-425	1	88	and	and	CCONJ
admet-425	1	89	biochemistry	biochemistry	NOUN
admet-425	1	90	,	,	PUNCT
admet-425	1	91	department	department	NOUN
admet-425	1	92	of	of	ADP
admet-425	1	93	pharmaceutical	pharmaceutical	NOUN
admet-425	1	94	technology	technology	NOUN
admet-425	1	95	,	,	PUNCT
admet-425	1	96	a.	a.	NOUN
admet-425	1	97	kovačića	kovačića	PROPN
admet-425	1	98	1	1	NUM
admet-425	1	99	,	,	PUNCT
admet-425	1	100	10	10	NUM
admet-425	1	101	000	000	NUM
admet-425	1	102	zagreb	zagreb	PROPN
admet-425	1	103	,	,	PUNCT
admet-425	1	104	croatia	croatia	PROPN
admet-425	1	105	2	2	NUM
admet-425	1	106	pliva	pliva	PROPN
admet-425	1	107	croatia	croatia	PROPN
admet-425	1	108	ltd	ltd	PROPN
admet-425	1	109	,	,	PUNCT
admet-425	1	110	teva	teva	PROPN
admet-425	1	111	group	group	PROPN
admet-425	1	112	member	member	PROPN
admet-425	1	113	,	,	PUNCT
admet-425	1	114	prilaz	prilaz	PROPN
admet-425	1	115	baruna	baruna	PROPN
admet-425	1	116	filipovića	filipovića	PROPN
admet-425	1	117	25	25	NUM
admet-425	1	118	,	,	PUNCT
admet-425	1	119	10000	10000	NUM
admet-425	1	120	zagreb	zagreb	PROPN
admet-425	1	121	,	,	PUNCT
admet-425	1	122	croatia	croatia	PROPN
admet-425	1	123	*	*	PUNCT
admet-425	1	124	corresponding	correspond	VERB
admet-425	1	125	author	author	NOUN
admet-425	1	126	:	:	PUNCT
admet-425	1	127	e	e	NOUN
admet-425	1	128	-	-	NOUN
admet-425	1	129	mail	mail	NOUN
admet-425	1	130	:	:	PUNCT
admet-425	1	131	mjug@pharma.hr	mjug@pharma.hr	PROPN
admet-425	1	132	,	,	PUNCT
admet-425	1	133	tel	tel	PROPN
admet-425	1	134	.	.	PUNCT
admet-425	1	135	:	:	PUNCT
admet-425	2	1	+385	+385	PROPN
admet-425	2	2	-	-	SYM
admet-425	2	3	1	1	NUM
admet-425	2	4	-	-	PUNCT
admet-425	2	5	6394	6394	NUM
admet-425	2	6	-	-	SYM
admet-425	2	7	764	764	NUM
admet-425	2	8	;	;	PUNCT
admet-425	2	9	fax	fax	NOUN
admet-425	2	10	:	:	PUNCT
admet-425	2	11	+385	+385	PROPN
admet-425	2	12	-	-	PUNCT
admet-425	2	13	1	1	NUM
admet-425	2	14	-	-	PUNCT
admet-425	2	15	4612	4612	NUM
admet-425	2	16	-	-	SYM
admet-425	2	17	691	691	NUM
admet-425	2	18	received	receive	VERB
admet-425	2	19	:	:	PUNCT
admet-425	2	20	august	august	PROPN
admet-425	2	21	29	29	NUM
admet-425	2	22	,	,	PUNCT
admet-425	2	23	2017	2017	NUM
admet-425	2	24	;	;	PUNCT
admet-425	2	25	revised	revise	VERB
admet-425	2	26	:	:	PUNCT
admet-425	2	27	september	september	PROPN
admet-425	2	28	19	19	NUM
admet-425	2	29	,	,	PUNCT
admet-425	2	30	2017	2017	NUM
admet-425	2	31	;	;	PUNCT
admet-425	2	32	published	publish	VERB
admet-425	2	33	:	:	PUNCT
admet-425	2	34	september	september	PROPN
admet-425	2	35	29	29	NUM
admet-425	2	36	,	,	PUNCT
admet-425	2	37	2017	2017	NUM
admet-425	2	38	abstract	abstract	NOUN
admet-425	2	39	in	in	ADP
admet-425	2	40	vitro	vitro	X
admet-425	2	41	dissolution	dissolution	NOUN
admet-425	2	42	/	/	SYM
admet-425	2	43	release	release	NOUN
admet-425	2	44	tests	test	NOUN
admet-425	2	45	are	be	AUX
admet-425	2	46	an	an	DET
admet-425	2	47	indispensable	indispensable	ADJ
admet-425	2	48	tool	tool	NOUN
admet-425	2	49	in	in	ADP
admet-425	2	50	the	the	DET
admet-425	2	51	drug	drug	NOUN
admet-425	2	52	product	product	NOUN
admet-425	2	53	development	development	NOUN
admet-425	2	54	,	,	PUNCT
admet-425	2	55	its	its	PRON
admet-425	2	56	quality	quality	NOUN
admet-425	2	57	control	control	NOUN
admet-425	2	58	and	and	CCONJ
admet-425	2	59	the	the	DET
admet-425	2	60	regulatory	regulatory	ADJ
admet-425	2	61	approval	approval	NOUN
admet-425	2	62	process	process	NOUN
admet-425	2	63	.	.	PUNCT
admet-425	3	1	mucosal	mucosal	ADJ
admet-425	3	2	drug	drug	NOUN
admet-425	3	3	delivery	delivery	NOUN
admet-425	3	4	systems	system	NOUN
admet-425	3	5	are	be	AUX
admet-425	3	6	designed	design	VERB
admet-425	3	7	to	to	PART
admet-425	3	8	provide	provide	VERB
admet-425	3	9	both	both	CCONJ
admet-425	3	10	local	local	ADJ
admet-425	3	11	and	and	CCONJ
admet-425	3	12	systemic	systemic	ADJ
admet-425	3	13	drug	drug	NOUN
admet-425	3	14	action	action	NOUN
admet-425	3	15	following	follow	VERB
admet-425	3	16	ocular	ocular	ADJ
admet-425	3	17	,	,	PUNCT
admet-425	3	18	nasal	nasal	NOUN
admet-425	3	19	,	,	PUNCT
admet-425	3	20	oromucosal	oromucosal	NOUN
admet-425	3	21	,	,	PUNCT
admet-425	3	22	vaginal	vaginal	ADJ
admet-425	3	23	or	or	CCONJ
admet-425	3	24	rectal	rectal	ADJ
admet-425	3	25	administration	administration	NOUN
admet-425	3	26	.	.	PUNCT
admet-425	4	1	they	they	PRON
admet-425	4	2	exhibit	exhibit	VERB
admet-425	4	3	significant	significant	ADJ
admet-425	4	4	differences	difference	NOUN
admet-425	4	5	in	in	ADP
admet-425	4	6	formulation	formulation	NOUN
admet-425	4	7	design	design	NOUN
admet-425	4	8	,	,	PUNCT
admet-425	4	9	physicochemical	physicochemical	ADJ
admet-425	4	10	characteristics	characteristic	NOUN
admet-425	4	11	and	and	CCONJ
admet-425	4	12	drug	drug	NOUN
admet-425	4	13	release	release	NOUN
admet-425	4	14	properties	property	NOUN
admet-425	4	15	.	.	PUNCT
admet-425	5	1	therefore	therefore	ADV
admet-425	5	2	it	it	PRON
admet-425	5	3	is	be	AUX
admet-425	5	4	not	not	PART
admet-425	5	5	possible	possible	ADJ
admet-425	5	6	to	to	PART
admet-425	5	7	devise	devise	VERB
admet-425	5	8	a	a	DET
admet-425	5	9	single	single	ADJ
admet-425	5	10	method	method	NOUN
admet-425	5	11	which	which	PRON
admet-425	5	12	would	would	AUX
admet-425	5	13	be	be	AUX
admet-425	5	14	suitable	suitable	ADJ
admet-425	5	15	for	for	ADP
admet-425	5	16	release	release	NOUN
admet-425	5	17	testing	testing	NOUN
admet-425	5	18	of	of	ADP
admet-425	5	19	such	such	ADJ
admet-425	5	20	versatile	versatile	ADJ
admet-425	5	21	and	and	CCONJ
admet-425	5	22	complex	complex	ADJ
admet-425	5	23	dosage	dosage	NOUN
admet-425	5	24	forms	form	NOUN
admet-425	5	25	.	.	PUNCT
admet-425	6	1	different	different	ADJ
admet-425	6	2	apparatuses	apparatus	NOUN
admet-425	6	3	and	and	CCONJ
admet-425	6	4	techniques	technique	NOUN
admet-425	6	5	for	for	ADP
admet-425	6	6	in	in	ADP
admet-425	6	7	vitro	vitro	X
admet-425	6	8	release	release	NOUN
admet-425	6	9	testing	testing	NOUN
admet-425	6	10	for	for	ADP
admet-425	6	11	mucosal	mucosal	NOUN
admet-425	6	12	delivery	delivery	NOUN
admet-425	6	13	systems	system	NOUN
admet-425	6	14	considering	consider	VERB
admet-425	6	15	the	the	DET
admet-425	6	16	specific	specific	ADJ
admet-425	6	17	conditions	condition	NOUN
admet-425	6	18	at	at	ADP
admet-425	6	19	the	the	DET
admet-425	6	20	administration	administration	NOUN
admet-425	6	21	site	site	NOUN
admet-425	6	22	are	be	AUX
admet-425	6	23	described	describe	VERB
admet-425	6	24	.	.	PUNCT
admet-425	7	1	in	in	ADP
admet-425	7	2	general	general	ADJ
admet-425	7	3	,	,	PUNCT
admet-425	7	4	compendial	compendial	ADJ
admet-425	7	5	apparatuses	apparatus	NOUN
admet-425	7	6	and	and	CCONJ
admet-425	7	7	methods	method	NOUN
admet-425	7	8	should	should	AUX
admet-425	7	9	be	be	AUX
admet-425	7	10	used	use	VERB
admet-425	7	11	as	as	ADP
admet-425	7	12	a	a	DET
admet-425	7	13	first	first	ADJ
admet-425	7	14	approach	approach	NOUN
admet-425	7	15	in	in	ADP
admet-425	7	16	method	method	NOUN
admet-425	7	17	development	development	NOUN
admet-425	7	18	when	when	SCONJ
admet-425	7	19	applicable	applicable	ADJ
admet-425	7	20	.	.	PUNCT
admet-425	8	1	however	however	ADV
admet-425	8	2	,	,	PUNCT
admet-425	8	3	to	to	PART
admet-425	8	4	assure	assure	VERB
admet-425	8	5	adequate	adequate	ADJ
admet-425	8	6	simulation	simulation	NOUN
admet-425	8	7	of	of	ADP
admet-425	8	8	conditions	condition	NOUN
admet-425	8	9	in	in	ADP
admet-425	8	10	vivo	vivo	NOUN
admet-425	8	11	,	,	PUNCT
admet-425	8	12	novel	novel	ADJ
admet-425	8	13	biorelevant	biorelevant	NOUN
admet-425	8	14	in	in	ADP
admet-425	8	15	vitro	vitro	X
admet-425	8	16	dissolution	dissolution	NOUN
admet-425	8	17	/	/	SYM
admet-425	8	18	release	release	NOUN
admet-425	8	19	methods	method	NOUN
admet-425	8	20	should	should	AUX
admet-425	8	21	be	be	AUX
admet-425	8	22	developed	develop	VERB
admet-425	8	23	.	.	PUNCT
admet-425	9	1	equipment	equipment	NOUN
admet-425	9	2	set	set	VERB
admet-425	9	3	up	up	ADP
admet-425	9	4	,	,	PUNCT
admet-425	9	5	the	the	DET
admet-425	9	6	selection	selection	NOUN
admet-425	9	7	of	of	ADP
admet-425	9	8	dissolution	dissolution	ADJ
admet-425	9	9	media	medium	NOUN
admet-425	9	10	and	and	CCONJ
admet-425	9	11	volume	volume	NOUN
admet-425	9	12	,	,	PUNCT
admet-425	9	13	membrane	membrane	NOUN
admet-425	9	14	type	type	NOUN
admet-425	9	15	,	,	PUNCT
admet-425	9	16	agitation	agitation	NOUN
admet-425	9	17	speed	speed	NOUN
admet-425	9	18	,	,	PUNCT
admet-425	9	19	temperature	temperature	NOUN
admet-425	9	20	,	,	PUNCT
admet-425	9	21	and	and	CCONJ
admet-425	9	22	assay	assay	VERB
admet-425	9	23	analysis	analysis	NOUN
admet-425	9	24	technique	technique	NOUN
admet-425	9	25	need	need	VERB
admet-425	9	26	to	to	PART
admet-425	9	27	be	be	AUX
admet-425	9	28	carefully	carefully	ADV
admet-425	9	29	defined	define	VERB
admet-425	9	30	based	base	VERB
admet-425	9	31	on	on	ADP
admet-425	9	32	mucosal	mucosal	ADJ
admet-425	9	33	drug	drug	NOUN
admet-425	9	34	delivery	delivery	NOUN
admet-425	9	35	system	system	NOUN
admet-425	9	36	characteristics	characteristic	NOUN
admet-425	9	37	.	.	PUNCT
admet-425	10	1	all	all	DET
admet-425	10	2	those	those	DET
admet-425	10	3	parameters	parameter	NOUN
admet-425	10	4	depend	depend	VERB
admet-425	10	5	on	on	ADP
admet-425	10	6	the	the	DET
admet-425	10	7	delivery	delivery	NOUN
admet-425	10	8	system	system	NOUN
admet-425	10	9	and	and	CCONJ
admet-425	10	10	physiological	physiological	ADJ
admet-425	10	11	conditions	condition	NOUN
admet-425	10	12	at	at	ADP
admet-425	10	13	the	the	DET
admet-425	10	14	site	site	NOUN
admet-425	10	15	of	of	ADP
admet-425	10	16	application	application	NOUN
admet-425	10	17	and	and	CCONJ
admet-425	10	18	may	may	AUX
admet-425	10	19	vary	vary	VERB
admet-425	10	20	in	in	ADP
admet-425	10	21	a	a	DET
admet-425	10	22	wide	wide	ADJ
admet-425	10	23	range	range	NOUN
admet-425	10	24	,	,	PUNCT
admet-425	10	25	which	which	PRON
admet-425	10	26	will	will	AUX
admet-425	10	27	be	be	AUX
admet-425	10	28	discussed	discuss	VERB
admet-425	10	29	in	in	ADP
admet-425	10	30	details	detail	NOUN
admet-425	10	31	.	.	PUNCT
admet-425	11	1	keywords	keyword	NOUN
admet-425	11	2	in	in	ADP
admet-425	11	3	vitro	vitro	X
admet-425	11	4	dissolution	dissolution	NOUN
admet-425	11	5	/	/	SYM
admet-425	11	6	release	release	NOUN
admet-425	11	7	test	test	NOUN
admet-425	11	8	;	;	PUNCT
admet-425	11	9	nasal	nasal	PROPN
admet-425	11	10	drug	drug	NOUN
admet-425	11	11	delivery	delivery	NOUN
admet-425	11	12	;	;	PUNCT
admet-425	11	13	ocular	ocular	ADJ
admet-425	11	14	drug	drug	NOUN
admet-425	11	15	delivery	delivery	NOUN
admet-425	11	16	;	;	PUNCT
admet-425	11	17	oromucosal	oromucosal	NOUN
admet-425	11	18	drug	drug	NOUN
admet-425	11	19	delivery	delivery	NOUN
admet-425	11	20	;	;	PUNCT
admet-425	11	21	rectal	rectal	ADJ
admet-425	11	22	drug	drug	NOUN
admet-425	11	23	delivery	delivery	NOUN
admet-425	11	24	;	;	PUNCT
admet-425	11	25	vaginal	vaginal	ADJ
admet-425	11	26	drug	drug	NOUN
admet-425	11	27	delivery	delivery	NOUN
admet-425	11	28	introduction	introduction	NOUN
admet-425	11	29	the	the	DET
admet-425	11	30	drug	drug	NOUN
admet-425	11	31	dissolution	dissolution	NOUN
admet-425	11	32	/	/	SYM
admet-425	11	33	release	release	NOUN
admet-425	11	34	test	test	NOUN
admet-425	11	35	is	be	AUX
admet-425	11	36	a	a	DET
admet-425	11	37	key	key	ADJ
admet-425	11	38	test	test	NOUN
admet-425	11	39	of	of	ADP
admet-425	11	40	dosage	dosage	NOUN
admet-425	11	41	form	form	NOUN
admet-425	11	42	performance	performance	NOUN
admet-425	11	43	both	both	CCONJ
admet-425	11	44	during	during	ADP
admet-425	11	45	formulation	formulation	NOUN
admet-425	11	46	development	development	NOUN
admet-425	11	47	as	as	ADV
admet-425	11	48	well	well	ADV
admet-425	11	49	as	as	ADP
admet-425	11	50	for	for	ADP
admet-425	11	51	quality	quality	NOUN
admet-425	11	52	control	control	NOUN
admet-425	11	53	purposes	purpose	NOUN
admet-425	11	54	.	.	PUNCT
admet-425	12	1	for	for	ADP
admet-425	12	2	majority	majority	NOUN
admet-425	12	3	of	of	ADP
admet-425	12	4	mucosal	mucosal	ADJ
admet-425	12	5	drug	drug	NOUN
admet-425	12	6	delivery	delivery	NOUN
admet-425	12	7	systems	system	NOUN
admet-425	12	8	(	(	PUNCT
admet-425	12	9	i.e.	i.e.	X
admet-425	12	10	formulations	formulation	NOUN
admet-425	12	11	aimed	aim	VERB
admet-425	12	12	to	to	PART
admet-425	12	13	provide	provide	VERB
admet-425	12	14	local	local	ADJ
admet-425	12	15	and/or	and/or	CCONJ
admet-425	12	16	systemic	systemic	ADJ
admet-425	12	17	drug	drug	NOUN
admet-425	12	18	action	action	NOUN
admet-425	12	19	via	via	ADP
admet-425	12	20	nasal	nasal	PROPN
admet-425	12	21	,	,	PUNCT
admet-425	12	22	ocular	ocular	ADJ
admet-425	12	23	,	,	PUNCT
admet-425	12	24	oral	oral	ADJ
admet-425	12	25	,	,	PUNCT
admet-425	12	26	rectal	rectal	ADJ
admet-425	12	27	and	and	CCONJ
admet-425	12	28	vaginal	vaginal	ADJ
admet-425	12	29	mucosa	mucosa	NOUN
admet-425	12	30	)	)	PUNCT
admet-425	12	31	the	the	DET
admet-425	12	32	methods	method	NOUN
admet-425	12	33	and	and	CCONJ
admet-425	12	34	apparatuses	apparatus	NOUN
admet-425	12	35	for	for	ADP
admet-425	12	36	dissolution	dissolution	NOUN
admet-425	12	37	/	/	SYM
admet-425	12	38	release	release	NOUN
admet-425	12	39	testing	testing	NOUN
admet-425	12	40	are	be	AUX
admet-425	12	41	not	not	PART
admet-425	12	42	standardized	standardize	VERB
admet-425	12	43	and	and	CCONJ
admet-425	12	44	described	describe	VERB
admet-425	12	45	in	in	ADP
admet-425	12	46	pharmacopoeial	pharmacopoeial	ADJ
admet-425	12	47	monographs	monograph	NOUN
admet-425	12	48	,	,	PUNCT
admet-425	12	49	indicating	indicate	VERB
admet-425	12	50	the	the	DET
admet-425	12	51	need	need	NOUN
admet-425	12	52	for	for	ADP
admet-425	12	53	further	further	ADJ
admet-425	12	54	development	development	NOUN
admet-425	12	55	and	and	CCONJ
admet-425	12	56	systematisation	systematisation	NOUN
admet-425	12	57	of	of	ADP
admet-425	12	58	the	the	DET
admet-425	12	59	currently	currently	ADV
admet-425	12	60	used	use	VERB
admet-425	12	61	methods	method	NOUN
admet-425	12	62	[	[	X
admet-425	12	63	1	1	NUM
admet-425	12	64	]	]	PUNCT
admet-425	12	65	.	.	PUNCT
admet-425	13	1	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-425	13	2	mailto:mjug@pharma.hr	mailto:mjug@pharma.hr	PROPN
admet-425	13	3	mario	mario	PROPN
admet-425	13	4	jug	jug	PROPN
admet-425	13	5	et	et	PROPN
admet-425	13	6	al	al	PROPN
admet-425	13	7	.	.	PROPN
admet-425	13	8	admet	admet	PROPN
admet-425	13	9	&	&	CCONJ
admet-425	13	10	dmpk	dmpk	PROPN
admet-425	13	11	5(3	5(3	NUM
admet-425	13	12	)	)	PUNCT
admet-425	13	13	(	(	PUNCT
admet-425	13	14	2017	2017	NUM
admet-425	13	15	)	)	PUNCT
admet-425	13	16	173	173	NUM
admet-425	13	17	-	-	SYM
admet-425	13	18	182	182	NUM
admet-425	13	19	174	174	NUM
admet-425	13	20	it	it	PRON
admet-425	13	21	should	should	AUX
admet-425	13	22	be	be	AUX
admet-425	13	23	noted	note	VERB
admet-425	13	24	that	that	SCONJ
admet-425	13	25	the	the	DET
admet-425	13	26	terms	term	NOUN
admet-425	13	27	drug	drug	VERB
admet-425	13	28	dissolution	dissolution	NOUN
admet-425	13	29	and	and	CCONJ
admet-425	13	30	drug	drug	NOUN
admet-425	13	31	release	release	NOUN
admet-425	13	32	are	be	AUX
admet-425	13	33	often	often	ADV
admet-425	13	34	not	not	PART
admet-425	13	35	appropriately	appropriately	ADV
admet-425	13	36	distinguished	distinguish	VERB
admet-425	13	37	in	in	ADP
admet-425	13	38	the	the	DET
admet-425	13	39	literature	literature	NOUN
admet-425	13	40	and	and	CCONJ
admet-425	13	41	even	even	ADV
admet-425	13	42	in	in	ADP
admet-425	13	43	regulatory	regulatory	ADJ
admet-425	13	44	documents	document	NOUN
admet-425	13	45	.	.	PUNCT
admet-425	14	1	the	the	DET
admet-425	14	2	drug	drug	NOUN
admet-425	14	3	dissolution	dissolution	NOUN
admet-425	14	4	process	process	NOUN
admet-425	14	5	refers	refer	VERB
admet-425	14	6	to	to	ADP
admet-425	14	7	all	all	DET
admet-425	14	8	formulations	formulation	NOUN
admet-425	14	9	in	in	ADP
admet-425	14	10	which	which	PRON
admet-425	14	11	the	the	DET
admet-425	14	12	drug	drug	NOUN
admet-425	14	13	is	be	AUX
admet-425	14	14	initially	initially	ADV
admet-425	14	15	present	present	ADJ
admet-425	14	16	in	in	ADP
admet-425	14	17	the	the	DET
admet-425	14	18	solid	solid	ADJ
admet-425	14	19	state	state	NOUN
admet-425	14	20	and	and	CCONJ
admet-425	14	21	encompasses	encompass	VERB
admet-425	14	22	5	5	NUM
admet-425	14	23	major	major	ADJ
admet-425	14	24	mass	mass	NOUN
admet-425	14	25	transport	transport	NOUN
admet-425	14	26	steps	step	NOUN
admet-425	14	27	:	:	PUNCT
admet-425	14	28	(	(	PUNCT
admet-425	14	29	i	i	NOUN
admet-425	14	30	)	)	PUNCT
admet-425	14	31	the	the	DET
admet-425	14	32	wetting	wetting	NOUN
admet-425	14	33	of	of	ADP
admet-425	14	34	the	the	DET
admet-425	14	35	particle	particle	NOUN
admet-425	14	36	surface	surface	NOUN
admet-425	14	37	with	with	ADP
admet-425	14	38	water	water	NOUN
admet-425	14	39	;	;	PUNCT
admet-425	14	40	(	(	PUNCT
admet-425	14	41	ii	ii	NOUN
admet-425	14	42	)	)	PUNCT
admet-425	14	43	breakdown	breakdown	NOUN
admet-425	14	44	of	of	ADP
admet-425	14	45	solid	solid	ADJ
admet-425	14	46	state	state	NOUN
admet-425	14	47	bonds	bond	NOUN
admet-425	14	48	in	in	ADP
admet-425	14	49	drug	drug	NOUN
admet-425	14	50	particle	particle	NOUN
admet-425	14	51	;	;	PUNCT
admet-425	14	52	(	(	PUNCT
admet-425	14	53	iii	iii	X
admet-425	14	54	)	)	PUNCT
admet-425	14	55	solvation	solvation	NOUN
admet-425	14	56	of	of	ADP
admet-425	14	57	the	the	DET
admet-425	14	58	individualized	individualized	ADJ
admet-425	14	59	species	specie	NOUN
admet-425	14	60	such	such	ADJ
admet-425	14	61	as	as	ADP
admet-425	14	62	ions	ion	NOUN
admet-425	14	63	or	or	CCONJ
admet-425	14	64	molecules	molecule	NOUN
admet-425	14	65	;	;	PUNCT
admet-425	14	66	(	(	PUNCT
admet-425	14	67	iv	iv	X
admet-425	14	68	)	)	PUNCT
admet-425	14	69	their	their	PRON
admet-425	14	70	diffusion	diffusion	NOUN
admet-425	14	71	through	through	ADP
admet-425	14	72	the	the	DET
admet-425	14	73	liquid	liquid	ADJ
admet-425	14	74	unstirred	unstirred	ADJ
admet-425	14	75	boundary	boundary	ADJ
admet-425	14	76	layer	layer	NOUN
admet-425	14	77	and	and	CCONJ
admet-425	14	78	(	(	PUNCT
admet-425	14	79	v	v	NOUN
admet-425	14	80	)	)	PUNCT
admet-425	14	81	convection	convection	NOUN
admet-425	14	82	within	within	ADP
admet-425	14	83	the	the	DET
admet-425	14	84	well	well	ADV
admet-425	14	85	-	-	PUNCT
admet-425	14	86	stirred	stir	VERB
admet-425	14	87	bulk	bulk	ADJ
admet-425	14	88	fluid	fluid	NOUN
admet-425	14	89	.	.	PUNCT
admet-425	15	1	if	if	SCONJ
admet-425	15	2	drug	drug	NOUN
admet-425	15	3	dissolution	dissolution	NOUN
admet-425	15	4	process	process	NOUN
admet-425	15	5	is	be	AUX
admet-425	15	6	the	the	DET
admet-425	15	7	rate	rate	NOUN
admet-425	15	8	-	-	PUNCT
admet-425	15	9	limiting	limit	VERB
admet-425	15	10	step	step	NOUN
admet-425	15	11	in	in	ADP
admet-425	15	12	the	the	DET
admet-425	15	13	overall	overall	ADJ
admet-425	15	14	release	release	NOUN
admet-425	15	15	process	process	NOUN
admet-425	15	16	,	,	PUNCT
admet-425	15	17	than	than	SCONJ
admet-425	15	18	the	the	DET
admet-425	15	19	terms	term	NOUN
admet-425	15	20	drug	drug	NOUN
admet-425	15	21	dissolution	dissolution	NOUN
admet-425	15	22	and	and	CCONJ
admet-425	15	23	drug	drug	NOUN
admet-425	15	24	release	release	NOUN
admet-425	15	25	can	can	AUX
admet-425	15	26	be	be	AUX
admet-425	15	27	considered	consider	VERB
admet-425	15	28	as	as	ADP
admet-425	15	29	synonyms	synonym	NOUN
admet-425	15	30	.	.	PUNCT
admet-425	16	1	in	in	ADP
admet-425	16	2	all	all	DET
admet-425	16	3	other	other	ADJ
admet-425	16	4	cases	case	NOUN
admet-425	16	5	,	,	PUNCT
admet-425	16	6	drug	drug	NOUN
admet-425	16	7	release	release	NOUN
admet-425	16	8	is	be	AUX
admet-425	16	9	the	the	DET
admet-425	16	10	more	more	ADV
admet-425	16	11	appropriate	appropriate	ADJ
admet-425	16	12	term	term	NOUN
admet-425	16	13	.	.	PUNCT
admet-425	17	1	in	in	ADP
admet-425	17	2	fact	fact	NOUN
admet-425	17	3	,	,	PUNCT
admet-425	17	4	the	the	DET
admet-425	17	5	drug	drug	NOUN
admet-425	17	6	release	release	NOUN
admet-425	17	7	is	be	AUX
admet-425	17	8	a	a	DET
admet-425	17	9	more	more	ADV
admet-425	17	10	complex	complex	ADJ
admet-425	17	11	phenomenon	phenomenon	NOUN
admet-425	17	12	,	,	PUNCT
admet-425	17	13	where	where	SCONJ
admet-425	17	14	drug	drug	NOUN
admet-425	17	15	dissolution	dissolution	NOUN
admet-425	17	16	is	be	AUX
admet-425	17	17	just	just	ADV
admet-425	17	18	one	one	NUM
admet-425	17	19	of	of	ADP
admet-425	17	20	its	its	PRON
admet-425	17	21	steps	step	NOUN
admet-425	17	22	.	.	PUNCT
admet-425	18	1	upon	upon	SCONJ
admet-425	18	2	the	the	DET
admet-425	18	3	contact	contact	NOUN
admet-425	18	4	with	with	ADP
admet-425	18	5	the	the	DET
admet-425	18	6	aqueous	aqueous	ADJ
admet-425	18	7	dissolution	dissolution	NOUN
admet-425	18	8	medium	medium	NOUN
admet-425	18	9	,	,	PUNCT
admet-425	18	10	water	water	NOUN
admet-425	18	11	penetrates	penetrate	VERB
admet-425	18	12	into	into	ADP
admet-425	18	13	the	the	DET
admet-425	18	14	matrix	matrix	NOUN
admet-425	18	15	of	of	ADP
admet-425	18	16	the	the	DET
admet-425	18	17	delivery	delivery	NOUN
admet-425	18	18	system	system	NOUN
admet-425	18	19	and	and	CCONJ
admet-425	18	20	dissolves	dissolve	VERB
admet-425	18	21	the	the	DET
admet-425	18	22	drug	drug	NOUN
admet-425	18	23	.	.	PUNCT
admet-425	19	1	the	the	DET
admet-425	19	2	dissolved	dissolve	VERB
admet-425	19	3	drug	drug	NOUN
admet-425	19	4	species	specie	NOUN
admet-425	19	5	subsequently	subsequently	ADV
admet-425	19	6	diffuse	diffuse	VERB
admet-425	19	7	out	out	ADP
admet-425	19	8	of	of	ADP
admet-425	19	9	the	the	DET
admet-425	19	10	matrix	matrix	NOUN
admet-425	19	11	of	of	ADP
admet-425	19	12	the	the	DET
admet-425	19	13	delivery	delivery	NOUN
admet-425	19	14	system	system	NOUN
admet-425	19	15	due	due	ADP
admet-425	19	16	to	to	ADP
admet-425	19	17	concentration	concentration	NOUN
admet-425	19	18	gradient	gradient	NOUN
admet-425	19	19	.	.	PUNCT
admet-425	20	1	additionally	additionally	ADV
admet-425	20	2	,	,	PUNCT
admet-425	20	3	the	the	DET
admet-425	20	4	matrix	matrix	NOUN
admet-425	20	5	of	of	ADP
admet-425	20	6	the	the	DET
admet-425	20	7	delivery	delivery	NOUN
admet-425	20	8	system	system	NOUN
admet-425	20	9	might	might	AUX
admet-425	20	10	also	also	ADV
admet-425	20	11	undergo	undergo	VERB
admet-425	20	12	several	several	ADJ
admet-425	20	13	changes	change	NOUN
admet-425	20	14	such	such	ADJ
admet-425	20	15	as	as	ADP
admet-425	20	16	swelling	swell	VERB
admet-425	20	17	and	and	CCONJ
admet-425	20	18	consequent	consequent	ADJ
admet-425	20	19	dissolution	dissolution	NOUN
admet-425	20	20	in	in	ADP
admet-425	20	21	the	the	DET
admet-425	20	22	aqueous	aqueous	ADJ
admet-425	20	23	medium	medium	NOUN
admet-425	20	24	,	,	PUNCT
admet-425	20	25	all	all	PRON
admet-425	20	26	contributing	contribute	VERB
admet-425	20	27	to	to	ADP
admet-425	20	28	the	the	DET
admet-425	20	29	overall	overall	ADJ
admet-425	20	30	drug	drug	NOUN
admet-425	20	31	release	release	NOUN
admet-425	20	32	process	process	NOUN
admet-425	20	33	[	[	X
admet-425	20	34	2,3	2,3	NUM
admet-425	20	35	]	]	PUNCT
admet-425	20	36	.	.	PUNCT
admet-425	21	1	considering	consider	VERB
admet-425	21	2	the	the	DET
admet-425	21	3	complexity	complexity	NOUN
admet-425	21	4	of	of	ADP
admet-425	21	5	mucosal	mucosal	ADJ
admet-425	21	6	delivery	delivery	NOUN
admet-425	21	7	systems	system	NOUN
admet-425	21	8	,	,	PUNCT
admet-425	21	9	often	often	ADV
admet-425	21	10	containing	contain	VERB
admet-425	21	11	nanoparticulate	nanoparticulate	ADJ
admet-425	21	12	carriers	carrier	NOUN
admet-425	21	13	included	include	VERB
admet-425	21	14	in	in	ADP
admet-425	21	15	soluble	soluble	ADJ
admet-425	21	16	or	or	CCONJ
admet-425	21	17	insoluble	insoluble	ADJ
admet-425	21	18	matrices	matrix	NOUN
admet-425	21	19	,	,	PUNCT
admet-425	21	20	in	in	ADP
admet-425	21	21	vitro	vitro	X
admet-425	21	22	drug	drug	NOUN
admet-425	21	23	release	release	NOUN
admet-425	21	24	seems	seem	VERB
admet-425	21	25	to	to	PART
admet-425	21	26	be	be	AUX
admet-425	21	27	the	the	DET
admet-425	21	28	appropriate	appropriate	ADJ
admet-425	21	29	term	term	NOUN
admet-425	21	30	when	when	SCONJ
admet-425	21	31	describing	describe	VERB
admet-425	21	32	the	the	DET
admet-425	21	33	liberation	liberation	NOUN
admet-425	21	34	process	process	NOUN
admet-425	21	35	of	of	ADP
admet-425	21	36	the	the	DET
admet-425	21	37	drug	drug	NOUN
admet-425	21	38	from	from	ADP
admet-425	21	39	such	such	ADJ
admet-425	21	40	formulations	formulation	NOUN
admet-425	21	41	.	.	PUNCT
admet-425	22	1	in	in	ADP
admet-425	22	2	methods	method	NOUN
admet-425	22	3	listed	list	VERB
admet-425	22	4	in	in	ADP
admet-425	22	5	usp	usp	NOUN
admet-425	22	6	and	and	CCONJ
admet-425	22	7	ph	ph	PROPN
admet-425	22	8	.	.	PROPN
admet-425	22	9	eur	eur	PROPN
admet-425	22	10	.	.	PUNCT
admet-425	23	1	monographs	monograph	NOUN
admet-425	23	2	,	,	PUNCT
admet-425	23	3	usp	usp	NOUN
admet-425	23	4	dissolution	dissolution	NOUN
admet-425	23	5	database	database	NOUN
admet-425	23	6	and	and	CCONJ
admet-425	23	7	fda	fda	PROPN
admet-425	23	8	dissolution	dissolution	PROPN
admet-425	23	9	database	database	NOUN
admet-425	23	10	(	(	PUNCT
admet-425	23	11	table	table	NOUN
admet-425	23	12	1	1	NUM
admet-425	23	13	)	)	PUNCT
admet-425	23	14	,	,	PUNCT
admet-425	23	15	the	the	DET
admet-425	23	16	apparatuses	apparatus	NOUN
admet-425	23	17	traditionally	traditionally	ADV
admet-425	23	18	used	use	VERB
admet-425	23	19	for	for	ADP
admet-425	23	20	oral	oral	ADJ
admet-425	23	21	formulations	formulation	NOUN
admet-425	23	22	are	be	AUX
admet-425	23	23	also	also	ADV
admet-425	23	24	often	often	ADV
admet-425	23	25	applied	apply	VERB
admet-425	23	26	for	for	ADP
admet-425	23	27	mucosal	mucosal	NOUN
admet-425	23	28	delivery	delivery	NOUN
admet-425	23	29	systems	system	NOUN
admet-425	23	30	.	.	PUNCT
admet-425	24	1	however	however	ADV
admet-425	24	2	,	,	PUNCT
admet-425	24	3	many	many	ADJ
admet-425	24	4	noncompendial	noncompendial	ADJ
admet-425	24	5	methods	method	NOUN
admet-425	24	6	have	have	AUX
admet-425	24	7	been	be	AUX
admet-425	24	8	developed	develop	VERB
admet-425	24	9	with	with	ADP
admet-425	24	10	intention	intention	NOUN
admet-425	24	11	to	to	PART
admet-425	24	12	take	take	VERB
admet-425	24	13	into	into	ADP
admet-425	24	14	account	account	NOUN
admet-425	24	15	the	the	DET
admet-425	24	16	specific	specific	ADJ
admet-425	24	17	physiochemical	physiochemical	ADJ
admet-425	24	18	properties	property	NOUN
admet-425	24	19	of	of	ADP
admet-425	24	20	the	the	DET
admet-425	24	21	formulation	formulation	NOUN
admet-425	24	22	and	and	CCONJ
admet-425	24	23	the	the	DET
admet-425	24	24	physiological	physiological	ADJ
admet-425	24	25	environment	environment	NOUN
admet-425	24	26	at	at	ADP
admet-425	24	27	which	which	PRON
admet-425	24	28	the	the	DET
admet-425	24	29	drug	drug	NOUN
admet-425	24	30	should	should	AUX
admet-425	24	31	be	be	AUX
admet-425	24	32	released	release	VERB
admet-425	24	33	.	.	PUNCT
admet-425	25	1	the	the	DET
admet-425	25	2	goal	goal	NOUN
admet-425	25	3	is	be	AUX
admet-425	25	4	to	to	PART
admet-425	25	5	develop	develop	VERB
admet-425	25	6	a	a	DET
admet-425	25	7	test	test	NOUN
admet-425	25	8	able	able	ADJ
admet-425	25	9	to	to	PART
admet-425	25	10	provide	provide	VERB
admet-425	25	11	predictive	predictive	ADJ
admet-425	25	12	estimation	estimation	NOUN
admet-425	25	13	of	of	ADP
admet-425	25	14	in	in	ADP
admet-425	25	15	vivo	vivo	ADJ
admet-425	25	16	drug	drug	NOUN
admet-425	25	17	product	product	NOUN
admet-425	25	18	performance	performance	NOUN
admet-425	25	19	,	,	PUNCT
admet-425	25	20	with	with	ADP
admet-425	25	21	preferably	preferably	ADV
admet-425	25	22	level	level	VERB
admet-425	25	23	a	a	PRON
admet-425	25	24	of	of	ADP
admet-425	25	25	in	in	ADP
admet-425	25	26	vitro	vitro	X
admet-425	25	27	-	-	PUNCT
admet-425	25	28	in	in	ADP
admet-425	25	29	vivo	vivo	NOUN
admet-425	25	30	correlation	correlation	NOUN
admet-425	25	31	(	(	PUNCT
admet-425	25	32	ivivc	ivivc	PROPN
admet-425	25	33	)	)	PUNCT
admet-425	26	1	[	[	X
admet-425	26	2	4	4	NUM
admet-425	26	3	]	]	PUNCT
admet-425	26	4	.	.	PUNCT
admet-425	27	1	development	development	NOUN
admet-425	27	2	of	of	ADP
admet-425	27	3	noncompendial	noncompendial	ADJ
admet-425	27	4	methodologies	methodology	NOUN
admet-425	27	5	requires	require	VERB
admet-425	27	6	standardization	standardization	NOUN
admet-425	27	7	of	of	ADP
admet-425	27	8	test	test	NOUN
admet-425	27	9	parameters	parameter	NOUN
admet-425	27	10	and	and	CCONJ
admet-425	27	11	procedures	procedure	NOUN
admet-425	27	12	in	in	ADP
admet-425	27	13	order	order	NOUN
admet-425	27	14	to	to	PART
admet-425	27	15	ensure	ensure	VERB
admet-425	27	16	reproducible	reproducible	ADJ
admet-425	27	17	and	and	CCONJ
admet-425	27	18	reliable	reliable	ADJ
admet-425	27	19	results	result	NOUN
admet-425	27	20	.	.	PUNCT
admet-425	28	1	besides	besides	SCONJ
admet-425	28	2	the	the	DET
admet-425	28	3	equipment	equipment	NOUN
admet-425	28	4	set	set	VERB
admet-425	28	5	up	up	ADP
admet-425	28	6	,	,	PUNCT
admet-425	28	7	selection	selection	NOUN
admet-425	28	8	of	of	ADP
admet-425	28	9	the	the	DET
admet-425	28	10	dissolution	dissolution	NOUN
admet-425	28	11	media	medium	NOUN
admet-425	28	12	and	and	CCONJ
admet-425	28	13	volume	volume	NOUN
admet-425	28	14	,	,	PUNCT
admet-425	28	15	membrane	membrane	NOUN
admet-425	28	16	type	type	NOUN
admet-425	28	17	,	,	PUNCT
admet-425	28	18	agitation	agitation	NOUN
admet-425	28	19	speed	speed	NOUN
admet-425	28	20	,	,	PUNCT
admet-425	28	21	temperature	temperature	NOUN
admet-425	28	22	,	,	PUNCT
admet-425	28	23	and	and	CCONJ
admet-425	28	24	assay	assay	VERB
admet-425	28	25	analysis	analysis	NOUN
admet-425	28	26	technique	technique	NOUN
admet-425	28	27	need	need	VERB
admet-425	28	28	to	to	PART
admet-425	28	29	be	be	AUX
admet-425	28	30	carefully	carefully	ADV
admet-425	28	31	defined	define	VERB
admet-425	28	32	based	base	VERB
admet-425	28	33	on	on	ADP
admet-425	28	34	mucosal	mucosal	ADJ
admet-425	28	35	drug	drug	NOUN
admet-425	28	36	delivery	delivery	NOUN
admet-425	28	37	system	system	NOUN
admet-425	28	38	characteristics	characteristic	NOUN
admet-425	28	39	and	and	CCONJ
admet-425	28	40	physiological	physiological	ADJ
admet-425	28	41	conditions	condition	NOUN
admet-425	28	42	at	at	ADP
admet-425	28	43	the	the	DET
admet-425	28	44	site	site	NOUN
admet-425	28	45	of	of	ADP
admet-425	28	46	application	application	NOUN
admet-425	28	47	[	[	X
admet-425	28	48	5	5	NUM
admet-425	28	49	]	]	PUNCT
admet-425	28	50	.	.	PUNCT
admet-425	29	1	this	this	DET
admet-425	29	2	article	article	NOUN
admet-425	29	3	is	be	AUX
admet-425	29	4	aimed	aim	VERB
admet-425	29	5	to	to	PART
admet-425	29	6	provide	provide	VERB
admet-425	29	7	useful	useful	ADJ
admet-425	29	8	guidelines	guideline	NOUN
admet-425	29	9	and	and	CCONJ
admet-425	29	10	recommendations	recommendation	NOUN
admet-425	29	11	in	in	ADP
admet-425	29	12	this	this	DET
admet-425	29	13	regard	regard	NOUN
admet-425	29	14	.	.	PUNCT
admet-425	30	1	the	the	DET
admet-425	30	2	dissolution	dissolution	ADJ
admet-425	30	3	medium	medium	ADJ
admet-425	30	4	selection	selection	NOUN
admet-425	30	5	as	as	SCONJ
admet-425	30	6	shown	show	VERB
admet-425	30	7	in	in	ADP
admet-425	30	8	table	table	NOUN
admet-425	30	9	1	1	NUM
admet-425	30	10	,	,	PUNCT
admet-425	30	11	apparatuses	apparatus	NOUN
admet-425	30	12	traditionally	traditionally	ADV
admet-425	30	13	used	use	VERB
admet-425	30	14	for	for	ADP
admet-425	30	15	oral	oral	ADJ
admet-425	30	16	formulations	formulation	NOUN
admet-425	30	17	are	be	AUX
admet-425	30	18	often	often	ADV
admet-425	30	19	applied	apply	VERB
admet-425	30	20	for	for	ADP
admet-425	30	21	mucosal	mucosal	NOUN
admet-425	30	22	delivery	delivery	NOUN
admet-425	30	23	systems	system	NOUN
admet-425	30	24	.	.	PUNCT
admet-425	31	1	generally	generally	ADV
admet-425	31	2	,	,	PUNCT
admet-425	31	3	the	the	DET
admet-425	31	4	relatively	relatively	ADV
admet-425	31	5	high	high	ADJ
admet-425	31	6	volume	volume	NOUN
admet-425	31	7	of	of	ADP
admet-425	31	8	the	the	DET
admet-425	31	9	dissolution	dissolution	NOUN
admet-425	31	10	medium	medium	NOUN
admet-425	31	11	used	used	ADJ
admet-425	31	12	(	(	PUNCT
admet-425	31	13	500	500	NUM
admet-425	31	14	-	-	SYM
admet-425	31	15	1000	1000	NUM
admet-425	31	16	ml	ml	NOUN
admet-425	31	17	)	)	PUNCT
admet-425	31	18	and	and	CCONJ
admet-425	31	19	the	the	DET
admet-425	31	20	hydrodynamics	hydrodynamic	NOUN
admet-425	31	21	provided	provide	VERB
admet-425	31	22	by	by	ADP
admet-425	31	23	such	such	ADJ
admet-425	31	24	apparatuses	apparatus	NOUN
admet-425	31	25	is	be	AUX
admet-425	31	26	not	not	PART
admet-425	31	27	in	in	ADP
admet-425	31	28	line	line	NOUN
admet-425	31	29	with	with	ADP
admet-425	31	30	the	the	DET
admet-425	31	31	in	in	ADP
admet-425	31	32	vivo	vivo	ADJ
admet-425	31	33	conditions	condition	NOUN
admet-425	31	34	at	at	ADP
admet-425	31	35	the	the	DET
admet-425	31	36	mucosal	mucosal	NOUN
admet-425	31	37	administration	administration	NOUN
admet-425	31	38	sites	site	NOUN
admet-425	31	39	.	.	PUNCT
admet-425	32	1	to	to	PART
admet-425	32	2	mimic	mimic	VERB
admet-425	32	3	the	the	DET
admet-425	32	4	physiological	physiological	ADJ
admet-425	32	5	conditions	condition	NOUN
admet-425	32	6	at	at	ADP
admet-425	32	7	mucosal	mucosal	NOUN
admet-425	32	8	administration	administration	NOUN
admet-425	32	9	sites	site	NOUN
admet-425	32	10	,	,	PUNCT
admet-425	32	11	a	a	DET
admet-425	32	12	low	low	ADJ
admet-425	32	13	volume	volume	NOUN
admet-425	32	14	of	of	ADP
admet-425	32	15	aqueous	aqueous	ADJ
admet-425	32	16	dissolution	dissolution	NOUN
admet-425	32	17	medium	medium	NOUN
admet-425	32	18	in	in	ADP
admet-425	32	19	the	the	DET
admet-425	32	20	physiological	physiological	ADJ
admet-425	32	21	ph	ph	NOUN
admet-425	32	22	range	range	NOUN
admet-425	32	23	should	should	AUX
admet-425	32	24	be	be	AUX
admet-425	32	25	used	use	VERB
admet-425	32	26	.	.	PUNCT
admet-425	33	1	some	some	PRON
admet-425	33	2	of	of	ADP
admet-425	33	3	the	the	DET
admet-425	33	4	commonly	commonly	ADV
admet-425	33	5	used	use	VERB
admet-425	33	6	dissolution	dissolution	NOUN
admet-425	33	7	media	medium	NOUN
admet-425	33	8	for	for	ADP
admet-425	33	9	mucosal	mucosal	NOUN
admet-425	33	10	delivery	delivery	NOUN
admet-425	33	11	systems	system	NOUN
admet-425	33	12	are	be	AUX
admet-425	33	13	listed	list	VERB
admet-425	33	14	in	in	ADP
admet-425	33	15	table	table	NOUN
admet-425	33	16	2	2	NUM
admet-425	33	17	.	.	PUNCT
admet-425	34	1	on	on	ADP
admet-425	34	2	the	the	DET
admet-425	34	3	other	other	ADJ
admet-425	34	4	hand	hand	NOUN
admet-425	34	5	,	,	PUNCT
admet-425	34	6	sink	sink	NOUN
admet-425	34	7	conditions	condition	NOUN
admet-425	34	8	should	should	AUX
admet-425	34	9	be	be	AUX
admet-425	34	10	maintained	maintain	VERB
admet-425	34	11	.	.	PUNCT
admet-425	35	1	in	in	ADP
admet-425	35	2	order	order	NOUN
admet-425	35	3	to	to	PART
admet-425	35	4	achieve	achieve	VERB
admet-425	35	5	sink	sink	NOUN
admet-425	35	6	conditions	condition	NOUN
admet-425	35	7	for	for	ADP
admet-425	35	8	a	a	DET
admet-425	35	9	water	water	NOUN
admet-425	35	10	-	-	PUNCT
admet-425	35	11	insoluble	insoluble	ADJ
admet-425	35	12	active	active	ADJ
admet-425	35	13	compound	compound	NOUN
admet-425	35	14	it	it	PRON
admet-425	35	15	may	may	AUX
admet-425	35	16	be	be	AUX
admet-425	35	17	necessary	necessary	ADJ
admet-425	35	18	to	to	PART
admet-425	35	19	add	add	VERB
admet-425	35	20	surfactants	surfactant	NOUN
admet-425	35	21	(	(	PUNCT
admet-425	35	22	such	such	ADJ
admet-425	35	23	as	as	ADP
admet-425	35	24	tween	tween	NOUN
admet-425	35	25	80	80	NUM
admet-425	35	26	or	or	CCONJ
admet-425	35	27	sodium	sodium	NOUN
admet-425	35	28	lauryl	lauryl	NOUN
admet-425	35	29	sulphate	sulphate	NOUN
admet-425	35	30	)	)	PUNCT
admet-425	35	31	,	,	PUNCT
admet-425	35	32	complexing	complexe	VERB
admet-425	35	33	agents	agent	NOUN
admet-425	35	34	(	(	PUNCT
admet-425	35	35	such	such	ADJ
admet-425	35	36	as	as	ADP
admet-425	35	37	cyclodextrins	cyclodextrin	NOUN
admet-425	35	38	)	)	PUNCT
admet-425	35	39	or	or	CCONJ
admet-425	35	40	organic	organic	ADJ
admet-425	35	41	solvents	solvent	NOUN
admet-425	35	42	(	(	PUNCT
admet-425	35	43	ethanol	ethanol	NOUN
admet-425	35	44	,	,	PUNCT
admet-425	35	45	methanol	methanol	NOUN
admet-425	35	46	etc	etc	X
admet-425	35	47	.	.	PUNCT
admet-425	35	48	)	)	PUNCT
admet-425	35	49	into	into	ADP
admet-425	35	50	the	the	DET
admet-425	35	51	dissolution	dissolution	NOUN
admet-425	35	52	medium	medium	NOUN
admet-425	35	53	[	[	X
admet-425	35	54	14	14	NUM
admet-425	35	55	]	]	PUNCT
admet-425	35	56	.	.	PUNCT
admet-425	36	1	if	if	SCONJ
admet-425	36	2	organic	organic	ADJ
admet-425	36	3	solvents	solvent	NOUN
admet-425	36	4	need	need	VERB
admet-425	36	5	to	to	PART
admet-425	36	6	be	be	AUX
admet-425	36	7	included	include	VERB
admet-425	36	8	in	in	ADP
admet-425	36	9	dissolution	dissolution	PROPN
admet-425	36	10	medium	medium	NOUN
admet-425	36	11	,	,	PUNCT
admet-425	36	12	they	they	PRON
admet-425	36	13	have	have	VERB
admet-425	36	14	to	to	PART
admet-425	36	15	be	be	AUX
admet-425	36	16	compatible	compatible	ADJ
admet-425	36	17	with	with	ADP
admet-425	36	18	the	the	DET
admet-425	36	19	formulation	formulation	NOUN
admet-425	36	20	,	,	PUNCT
admet-425	36	21	and	and	CCONJ
admet-425	36	22	their	their	PRON
admet-425	36	23	concentration	concentration	NOUN
admet-425	36	24	needs	need	VERB
admet-425	36	25	to	to	PART
admet-425	36	26	be	be	AUX
admet-425	36	27	adjusted	adjust	VERB
admet-425	36	28	not	not	PART
admet-425	36	29	to	to	PART
admet-425	36	30	disrupt	disrupt	VERB
admet-425	36	31	the	the	DET
admet-425	36	32	formulation	formulation	NOUN
admet-425	36	33	.	.	PUNCT
admet-425	37	1	in	in	ADP
admet-425	37	2	addition	addition	NOUN
admet-425	37	3	,	,	PUNCT
admet-425	37	4	in	in	ADP
admet-425	37	5	case	case	NOUN
admet-425	37	6	of	of	ADP
admet-425	37	7	membrane	membrane	NOUN
admet-425	37	8	diffusion	diffusion	NOUN
admet-425	37	9	methods	method	NOUN
admet-425	37	10	,	,	PUNCT
admet-425	37	11	the	the	DET
admet-425	37	12	selected	select	VERB
admet-425	37	13	solvent	solvent	NOUN
admet-425	37	14	should	should	AUX
admet-425	37	15	also	also	ADV
admet-425	37	16	be	be	AUX
admet-425	37	17	compatible	compatible	ADJ
admet-425	37	18	with	with	ADP
admet-425	37	19	the	the	DET
admet-425	37	20	membrane	membrane	NOUN
admet-425	37	21	used	use	VERB
admet-425	37	22	[	[	X
admet-425	37	23	15	15	NUM
admet-425	37	24	]	]	PUNCT
admet-425	37	25	.	.	PUNCT
admet-425	38	1	the	the	DET
admet-425	38	2	most	most	ADV
admet-425	38	3	commonly	commonly	ADV
admet-425	38	4	applied	apply	VERB
admet-425	38	5	temperature	temperature	NOUN
admet-425	38	6	for	for	ADP
admet-425	38	7	oromucosal	oromucosal	NOUN
admet-425	38	8	,	,	PUNCT
admet-425	38	9	rectal	rectal	ADJ
admet-425	38	10	and	and	CCONJ
admet-425	38	11	vaginal	vaginal	ADJ
admet-425	38	12	formulations	formulation	NOUN
admet-425	38	13	testing	testing	NOUN
admet-425	38	14	is	be	AUX
admet-425	38	15	37	37	NUM
admet-425	38	16	°	°	NOUN
admet-425	38	17	c	c	NOUN
admet-425	38	18	,	,	PUNCT
admet-425	38	19	while	while	SCONJ
admet-425	38	20	in	in	ADP
admet-425	38	21	admet	admet	PROPN
admet-425	38	22	&	&	CCONJ
admet-425	38	23	dmpk	dmpk	PROPN
admet-425	38	24	5(3	5(3	NUM
admet-425	38	25	)	)	PUNCT
admet-425	38	26	(	(	PUNCT
admet-425	38	27	2017	2017	NUM
admet-425	38	28	)	)	PUNCT
admet-425	38	29	173	173	NUM
admet-425	38	30	-	-	SYM
admet-425	38	31	182	182	NUM
admet-425	38	32	in	in	ADP
admet-425	38	33	vitro	vitro	X
admet-425	38	34	release	release	NOUN
admet-425	38	35	testing	testing	NOUN
admet-425	38	36	of	of	ADP
admet-425	38	37	mucosal	mucosal	ADJ
admet-425	38	38	drug	drug	NOUN
admet-425	38	39	delivery	delivery	NOUN
admet-425	38	40	systems	system	NOUN
admet-425	38	41	doi	doi	NOUN
admet-425	38	42	:	:	PUNCT
admet-425	38	43	10.5599	10.5599	NUM
admet-425	38	44	/	/	SYM
admet-425	38	45	admet.5.3.425	admet.5.3.425	NUM
admet-425	38	46	175	175	NUM
admet-425	38	47	case	case	NOUN
admet-425	38	48	of	of	ADP
admet-425	38	49	ocular	ocular	ADJ
admet-425	38	50	and	and	CCONJ
admet-425	38	51	nasal	nasal	NOUN
admet-425	38	52	formulations	formulation	NOUN
admet-425	38	53	,	,	PUNCT
admet-425	38	54	temperature	temperature	NOUN
admet-425	38	55	may	may	AUX
admet-425	38	56	wary	wary	VERB
admet-425	38	57	between	between	ADP
admet-425	38	58	32	32	NUM
admet-425	38	59	-	-	SYM
admet-425	38	60	34	34	NUM
admet-425	38	61	and	and	CCONJ
admet-425	38	62	33	33	NUM
admet-425	38	63	-	-	SYM
admet-425	38	64	37	37	NUM
admet-425	38	65	°	°	NOUN
admet-425	38	66	c	c	NOUN
admet-425	38	67	,	,	PUNCT
admet-425	38	68	respectively	respectively	ADV
admet-425	38	69	[	[	X
admet-425	38	70	3	3	NUM
admet-425	38	71	]	]	PUNCT
admet-425	38	72	.	.	PUNCT
admet-425	39	1	table	table	NOUN
admet-425	39	2	1	1	NUM
admet-425	39	3	.	.	PUNCT
admet-425	40	1	apparatuses	apparatus	NOUN
admet-425	40	2	used	use	VERB
admet-425	40	3	/	/	PUNCT
admet-425	40	4	recommended	recommend	VERB
admet-425	40	5	for	for	ADP
admet-425	40	6	in	in	ADP
admet-425	40	7	vitro	vitro	X
admet-425	40	8	release	release	NOUN
admet-425	40	9	testing	testing	NOUN
admet-425	40	10	of	of	ADP
admet-425	40	11	mucosal	mucosal	NOUN
admet-425	40	12	formulations	formulation	NOUN
admet-425	40	13	according	accord	VERB
admet-425	40	14	to	to	ADP
admet-425	40	15	monographs	monograph	NOUN
admet-425	40	16	and	and	CCONJ
admet-425	40	17	methods	method	NOUN
admet-425	40	18	published	publish	VERB
admet-425	40	19	by	by	ADP
admet-425	40	20	usp	usp	PROPN
admet-425	40	21	,	,	PUNCT
admet-425	40	22	ph	ph	PROPN
admet-425	40	23	.	.	PROPN
admet-425	40	24	eur	eur	PROPN
admet-425	40	25	.	.	PUNCT
admet-425	41	1	and	and	CCONJ
admet-425	41	2	fda	fda	PROPN
admet-425	41	3	.	.	PROPN
admet-425	41	4	reprinted	reprint	VERB
admet-425	41	5	from	from	ADP
admet-425	41	6	ref	ref	NOUN
admet-425	41	7	.	.	PUNCT
admet-425	42	1	[	[	X
admet-425	42	2	3	3	X
admet-425	42	3	]	]	PUNCT
admet-425	42	4	with	with	ADP
admet-425	42	5	permission	permission	NOUN
admet-425	42	6	of	of	ADP
admet-425	42	7	elsevier	elsevier	NOUN
admet-425	42	8	.	.	PUNCT
admet-425	43	1	formulation	formulation	NOUN
admet-425	43	2	type	type	NOUN
admet-425	43	3	apparatus	apparatus	NOUN
admet-425	43	4	reference	reference	NOUN
admet-425	43	5	semisolid	semisolid	NOUN
admet-425	43	6	dosage	dosage	NOUN
admet-425	43	7	forms	form	NOUN
admet-425	43	8	(	(	PUNCT
admet-425	43	9	creams	cream	NOUN
admet-425	43	10	,	,	PUNCT
admet-425	43	11	gels	gel	NOUN
admet-425	43	12	,	,	PUNCT
admet-425	43	13	ointments	ointment	NOUN
admet-425	43	14	,	,	PUNCT
admet-425	43	15	lotions	lotion	NOUN
admet-425	43	16	)	)	PUNCT
admet-425	43	17	vertical	vertical	ADJ
admet-425	43	18	diffusion	diffusion	NOUN
admet-425	43	19	cell	cell	NOUN
admet-425	43	20	[	[	X
admet-425	43	21	6	6	NUM
admet-425	43	22	]	]	SYM
admet-425	43	23	immersion	immersion	NOUN
admet-425	43	24	cell	cell	NOUN
admet-425	43	25	[	[	X
admet-425	43	26	6	6	NUM
admet-425	43	27	]	]	PUNCT
admet-425	43	28	flow	flow	NOUN
admet-425	43	29	through	through	ADP
admet-425	43	30	cell	cell	NOUN
admet-425	43	31	with	with	ADP
admet-425	43	32	adapter	adapter	NOUN
admet-425	43	33	for	for	ADP
admet-425	43	34	semisolid	semisolid	NOUN
admet-425	43	35	dosage	dosage	NOUN
admet-425	43	36	forms	form	NOUN
admet-425	43	37	[	[	X
admet-425	43	38	6	6	NUM
admet-425	43	39	]	]	PUNCT
admet-425	43	40	paddle	paddle	NOUN
admet-425	43	41	apparatus	apparatus	NOUN
admet-425	43	42	[	[	X
admet-425	43	43	7	7	NUM
admet-425	43	44	]	]	X
admet-425	43	45	oral	oral	ADJ
admet-425	43	46	,	,	PUNCT
admet-425	43	47	buccal	buccal	ADJ
admet-425	43	48	and	and	CCONJ
admet-425	43	49	sublingual	sublingual	ADJ
admet-425	43	50	films	film	NOUN
admet-425	43	51	paddle	paddle	VERB
admet-425	43	52	over	over	ADP
admet-425	43	53	disk	disk	NOUN
admet-425	43	54	apparatus	apparatus	NOUN
admet-425	43	55	[	[	X
admet-425	43	56	7–10	7–10	X
admet-425	43	57	]	]	X
admet-425	43	58	basket	basket	NOUN
admet-425	43	59	apparatus	apparatus	NOUN
admet-425	43	60	(	(	PUNCT
admet-425	43	61	small	small	ADJ
admet-425	43	62	-	-	PUNCT
admet-425	43	63	volume	volume	NOUN
admet-425	43	64	configuration	configuration	NOUN
admet-425	43	65	)	)	PUNCT
admet-425	44	1	[	[	X
admet-425	44	2	7,8	7,8	NUM
admet-425	44	3	]	]	SYM
admet-425	44	4	sublingual	sublingual	ADJ
admet-425	44	5	and	and	CCONJ
admet-425	44	6	buccal	buccal	ADJ
admet-425	44	7	tablets	tablet	NOUN
admet-425	44	8	paddle	paddle	NOUN
admet-425	44	9	apparatus	apparatus	NOUN
admet-425	44	10	(	(	PUNCT
admet-425	44	11	standard	standard	ADJ
admet-425	44	12	or	or	CCONJ
admet-425	44	13	small	small	ADJ
admet-425	44	14	-	-	PUNCT
admet-425	44	15	volume	volume	NOUN
admet-425	44	16	configuration	configuration	NOUN
admet-425	44	17	)	)	PUNCT
admet-425	45	1	[	[	X
admet-425	45	2	7,8,11	7,8,11	NUM
admet-425	45	3	]	]	PUNCT
admet-425	45	4	basket	basket	NOUN
admet-425	45	5	apparatus	apparatus	NOUN
admet-425	45	6	(	(	PUNCT
admet-425	45	7	standard	standard	ADJ
admet-425	45	8	or	or	CCONJ
admet-425	45	9	small	small	ADJ
admet-425	45	10	-	-	PUNCT
admet-425	45	11	volume	volume	NOUN
admet-425	45	12	configuration	configuration	NOUN
admet-425	45	13	)	)	PUNCT
admet-425	46	1	[	[	X
admet-425	46	2	7,8	7,8	NUM
admet-425	46	3	]	]	PUNCT
admet-425	46	4	lozenges	lozenge	VERB
admet-425	46	5	basket	basket	NOUN
admet-425	46	6	apparatus	apparatus	NOUN
admet-425	46	7	[	[	X
admet-425	46	8	7,8	7,8	NUM
admet-425	46	9	]	]	PUNCT
admet-425	46	10	paddle	paddle	NOUN
admet-425	46	11	apparatus	apparatus	NOUN
admet-425	46	12	[	[	X
admet-425	46	13	7,8,11	7,8,11	NUM
admet-425	46	14	]	]	PUNCT
admet-425	46	15	reciprocating	reciprocate	VERB
admet-425	46	16	cylinder	cylinder	NOUN
admet-425	46	17	[	[	X
admet-425	46	18	7,8	7,8	NUM
admet-425	46	19	]	]	PUNCT
admet-425	46	20	medicated	medicate	VERB
admet-425	46	21	chewing	chewing	NOUN
admet-425	46	22	gums	gum	NOUN
admet-425	46	23	dissolution	dissolution	NOUN
admet-425	46	24	apparatus	apparatus	NOUN
admet-425	46	25	for	for	ADP
admet-425	46	26	chewing	chew	VERB
admet-425	46	27	gums	gum	NOUN
admet-425	46	28	[	[	X
admet-425	46	29	7,8,12	7,8,12	NUM
admet-425	46	30	]	]	X
admet-425	46	31	suppositories	suppository	NOUN
admet-425	46	32	(	(	PUNCT
admet-425	46	33	hydrophilic	hydrophilic	ADJ
admet-425	46	34	)	)	PUNCT
admet-425	46	35	paddle	paddle	NOUN
admet-425	46	36	apparatus	apparatus	NOUN
admet-425	46	37	[	[	X
admet-425	46	38	7,8,11	7,8,11	NUM
admet-425	46	39	]	]	PUNCT
admet-425	46	40	basket	basket	NOUN
admet-425	46	41	apparatus	apparatus	NOUN
admet-425	46	42	(	(	PUNCT
admet-425	46	43	standard	standard	ADJ
admet-425	46	44	or	or	CCONJ
admet-425	46	45	palmieri	palmieri	NOUN
admet-425	46	46	type	type	NOUN
admet-425	46	47	basket	basket	NOUN
admet-425	46	48	)	)	PUNCT
admet-425	47	1	[	[	X
admet-425	47	2	7,8	7,8	NUM
admet-425	47	3	]	]	PUNCT
admet-425	47	4	flow	flow	NOUN
admet-425	47	5	-	-	PUNCT
admet-425	47	6	through	through	ADP
admet-425	47	7	cell	cell	NOUN
admet-425	47	8	[	[	X
admet-425	47	9	8	8	NUM
admet-425	47	10	]	]	PUNCT
admet-425	47	11	suppositories	suppository	NOUN
admet-425	47	12	(	(	PUNCT
admet-425	47	13	lipophilic	lipophilic	ADJ
admet-425	47	14	)	)	PUNCT
admet-425	47	15	dual	dual	ADJ
admet-425	47	16	chamber	chamber	NOUN
admet-425	47	17	flow	flow	NOUN
admet-425	47	18	-	-	PUNCT
admet-425	47	19	through	through	ADP
admet-425	47	20	cell	cell	NOUN
admet-425	47	21	[	[	X
admet-425	47	22	8,13	8,13	NUM
admet-425	47	23	]	]	X
admet-425	47	24	vaginal	vaginal	ADJ
admet-425	47	25	tablets	tablet	NOUN
admet-425	47	26	and	and	CCONJ
admet-425	47	27	vaginal	vaginal	ADJ
admet-425	47	28	inserts	insert	NOUN
admet-425	47	29	paddle	paddle	NOUN
admet-425	47	30	apparatus	apparatus	NOUN
admet-425	47	31	[	[	X
admet-425	47	32	7,8	7,8	NUM
admet-425	47	33	]	]	PUNCT
admet-425	47	34	basket	basket	NOUN
admet-425	47	35	apparatus	apparatus	NOUN
admet-425	47	36	[	[	X
admet-425	47	37	7,8,11	7,8,11	NUM
admet-425	47	38	]	]	X
admet-425	47	39	vaginal	vaginal	ADJ
admet-425	47	40	rings	ring	NOUN
admet-425	47	41	incubator	incubator	NOUN
admet-425	47	42	shaker	shaker	NOUN
admet-425	47	43	[	[	X
admet-425	47	44	7	7	X
admet-425	47	45	]	]	PUNCT
admet-425	47	46	mucosal	mucosal	NOUN
admet-425	47	47	suspensions	suspension	NOUN
admet-425	47	48	paddle	paddle	NOUN
admet-425	47	49	apparatus	apparatus	NOUN
admet-425	47	50	(	(	PUNCT
admet-425	47	51	standard	standard	ADJ
admet-425	47	52	or	or	CCONJ
admet-425	47	53	small	small	ADJ
admet-425	47	54	-	-	PUNCT
admet-425	47	55	volume	volume	NOUN
admet-425	47	56	configuration	configuration	NOUN
admet-425	47	57	)	)	PUNCT
admet-425	48	1	[	[	X
admet-425	48	2	7,8	7,8	NUM
admet-425	48	3	]	]	PUNCT
admet-425	48	4	mucosal	mucosal	NOUN
admet-425	48	5	emulsions	emulsion	NOUN
admet-425	48	6	paddle	paddle	NOUN
admet-425	48	7	apparatus	apparatus	NOUN
admet-425	48	8	[	[	X
admet-425	48	9	8	8	NUM
admet-425	48	10	]	]	X
admet-425	48	11	vertical	vertical	ADJ
admet-425	48	12	diffusion	diffusion	NOUN
admet-425	48	13	cell	cell	NOUN
admet-425	49	1	[	[	X
admet-425	49	2	8	8	NUM
admet-425	49	3	]	]	X
admet-425	49	4	ocular	ocular	ADJ
admet-425	49	5	systems	system	NOUN
admet-425	49	6	reciprocating	reciprocate	VERB
admet-425	49	7	shaker	shaker	NOUN
admet-425	49	8	[	[	X
admet-425	49	9	11	11	NUM
admet-425	49	10	]	]	X
admet-425	49	11	periodontal	periodontal	ADJ
admet-425	49	12	systems	system	NOUN
admet-425	49	13	tube	tube	NOUN
admet-425	49	14	rotator	rotator	NOUN
admet-425	49	15	[	[	X
admet-425	49	16	11	11	NUM
admet-425	49	17	]	]	SYM
admet-425	49	18	table	table	NOUN
admet-425	49	19	2	2	NUM
admet-425	49	20	.	.	PUNCT
admet-425	50	1	some	some	PRON
admet-425	50	2	frequently	frequently	ADV
admet-425	50	3	used	use	VERB
admet-425	50	4	dissolution	dissolution	NOUN
admet-425	50	5	media	medium	NOUN
admet-425	50	6	for	for	ADP
admet-425	50	7	in	in	ADP
admet-425	50	8	vitro	vitro	X
admet-425	50	9	drug	drug	NOUN
admet-425	50	10	release	release	NOUN
admet-425	50	11	testing	testing	NOUN
admet-425	50	12	of	of	ADP
admet-425	50	13	mucosal	mucosal	ADJ
admet-425	50	14	drug	drug	NOUN
admet-425	50	15	delivery	delivery	NOUN
admet-425	50	16	systems	system	NOUN
admet-425	50	17	.	.	PUNCT
admet-425	51	1	reprinted	reprint	VERB
admet-425	51	2	from	from	ADP
admet-425	51	3	ref	ref	NOUN
admet-425	51	4	.	.	PUNCT
admet-425	52	1	[	[	X
admet-425	52	2	3	3	X
admet-425	52	3	]	]	PUNCT
admet-425	52	4	with	with	ADP
admet-425	52	5	permission	permission	NOUN
admet-425	52	6	of	of	ADP
admet-425	52	7	elsevier	elsevier	NOUN
admet-425	52	8	.	.	PUNCT
admet-425	53	1	medium	medium	ADJ
admet-425	53	2	composition	composition	NOUN
admet-425	53	3	ph	ph	NOUN
admet-425	53	4	reference	reference	NOUN
admet-425	53	5	simulated	simulate	VERB
admet-425	53	6	tear	tear	ADJ
admet-425	53	7	fluid	fluid	NOUN
admet-425	53	8	2.18	2.18	NUM
admet-425	53	9	g	g	NOUN
admet-425	53	10	nahco3	nahco3	NOUN
admet-425	53	11	,	,	PUNCT
admet-425	53	12	6.78	6.78	NUM
admet-425	53	13	g	g	NOUN
admet-425	53	14	nacl	nacl	NOUN
admet-425	53	15	,	,	PUNCT
admet-425	53	16	0.063	0.063	NUM
admet-425	53	17	g	g	NOUN
admet-425	53	18	cacl2	cacl2	NOUN
admet-425	53	19	,	,	PUNCT
admet-425	53	20	1.38	1.38	NUM
admet-425	53	21	g	g	NOUN
admet-425	53	22	kcl	kcl	NOUN
admet-425	53	23	and	and	CCONJ
admet-425	53	24	distilled	distil	VERB
admet-425	53	25	water	water	NOUN
admet-425	53	26	up	up	ADP
admet-425	53	27	to	to	ADP
admet-425	53	28	1000	1000	NUM
admet-425	53	29	ml	ml	ADP
admet-425	53	30	7.4	7.4	NUM
admet-425	54	1	[	[	SYM
admet-425	54	2	16	16	NUM
admet-425	54	3	]	]	PUNCT
admet-425	54	4	simulated	simulate	VERB
admet-425	54	5	nasal	nasal	PROPN
admet-425	54	6	fluid	fluid	NOUN
admet-425	54	7	8.77	8.77	NUM
admet-425	54	8	g	g	NOUN
admet-425	54	9	nacl	nacl	NOUN
admet-425	54	10	,	,	PUNCT
admet-425	54	11	2.98	2.98	NUM
admet-425	54	12	g	g	NOUN
admet-425	54	13	kcl	kcl	NOUN
admet-425	54	14	,	,	PUNCT
admet-425	54	15	0.59	0.59	NUM
admet-425	54	16	g	g	NOUN
admet-425	54	17	cacl2	cacl2	NOUN
admet-425	54	18	and	and	CCONJ
admet-425	54	19	distilled	distil	VERB
admet-425	54	20	water	water	NOUN
admet-425	54	21	up	up	ADP
admet-425	54	22	to	to	ADP
admet-425	54	23	1000	1000	NUM
admet-425	54	24	ml	ml	NOUN
admet-425	54	25	5.5	5.5	NUM
admet-425	54	26	[	[	SYM
admet-425	54	27	17	17	NUM
admet-425	54	28	]	]	PUNCT
admet-425	54	29	simulated	simulate	VERB
admet-425	54	30	nasal	nasal	PROPN
admet-425	54	31	electrolyte	electrolyte	PROPN
admet-425	54	32	solution	solution	NOUN
admet-425	54	33	7.45	7.45	NUM
admet-425	54	34	g	g	PROPN
admet-425	54	35	nacl	nacl	NOUN
admet-425	54	36	,	,	PUNCT
admet-425	54	37	1.29	1.29	NUM
admet-425	54	38	g	g	NOUN
admet-425	54	39	kcl	kcl	NOUN
admet-425	54	40	,	,	PUNCT
admet-425	54	41	0.32	0.32	NUM
admet-425	54	42	cacl2x2h2o	cacl2x2h2o	NOUN
admet-425	54	43	and	and	CCONJ
admet-425	54	44	distilled	distil	VERB
admet-425	54	45	water	water	NOUN
admet-425	54	46	up	up	ADP
admet-425	54	47	to	to	ADP
admet-425	54	48	1000	1000	NUM
admet-425	54	49	ml	ml	ADP
admet-425	54	50	5.5	5.5	NUM
admet-425	54	51	-	-	SYM
admet-425	54	52	6.5	6.5	NUM
admet-425	54	53	[	[	SYM
admet-425	54	54	18	18	NUM
admet-425	54	55	]	]	PUNCT
admet-425	54	56	artificial	artificial	ADJ
admet-425	54	57	nasal	nasal	NOUN
admet-425	54	58	electrolyte	electrolyte	PROPN
admet-425	54	59	0.8	0.8	NUM
admet-425	54	60	g	g	NOUN
admet-425	54	61	nacl	nacl	NOUN
admet-425	54	62	,	,	PUNCT
admet-425	54	63	3.0	3.0	NUM
admet-425	54	64	g	g	NOUN
admet-425	54	65	kcl	kcl	NOUN
admet-425	54	66	,	,	PUNCT
admet-425	54	67	0.45	0.45	NUM
admet-425	54	68	g	g	NOUN
admet-425	54	69	cacl2	cacl2	NOUN
admet-425	54	70	and	and	CCONJ
admet-425	54	71	distilled	distil	VERB
admet-425	54	72	water	water	NOUN
admet-425	54	73	up	up	ADP
admet-425	54	74	to	to	ADP
admet-425	54	75	1000	1000	NUM
admet-425	54	76	ml	ml	ADP
admet-425	54	77	6.8	6.8	NUM
admet-425	54	78	[	[	SYM
admet-425	54	79	19	19	NUM
admet-425	54	80	]	]	X
admet-425	54	81	nasal	nasal	ADJ
admet-425	54	82	fluid	fluid	ADJ
admet-425	54	83	simulant	simulant	NOUN
admet-425	54	84	7.13	7.13	NUM
admet-425	54	85	g	g	PROPN
admet-425	54	86	nacl	nacl	NOUN
admet-425	54	87	,	,	PUNCT
admet-425	54	88	2.98	2.98	NUM
admet-425	54	89	g	g	NOUN
admet-425	54	90	kcl	kcl	NOUN
admet-425	54	91	,	,	PUNCT
admet-425	54	92	2.14	2.14	NUM
admet-425	54	93	g	g	ADP
admet-425	54	94	nah2po4xh20	nah2po4xh20	PROPN
admet-425	54	95	,	,	PUNCT
admet-425	54	96	1.21	1.21	NUM
admet-425	54	97	g	g	PROPN
admet-425	54	98	na2hpo4x7h2o	na2hpo4x7h2o	NOUN
admet-425	54	99	and	and	CCONJ
admet-425	54	100	distilled	distil	VERB
admet-425	54	101	water	water	NOUN
admet-425	54	102	up	up	ADP
admet-425	54	103	to	to	ADP
admet-425	54	104	1000	1000	NUM
admet-425	54	105	ml	ml	ADP
admet-425	54	106	7.4	7.4	NUM
admet-425	54	107	[	[	SYM
admet-425	54	108	20	20	NUM
admet-425	54	109	]	]	PUNCT
admet-425	54	110	simulated	simulate	VERB
admet-425	54	111	saliva	saliva	NOUN
admet-425	54	112	2.38	2.38	NUM
admet-425	54	113	g	g	PROPN
admet-425	54	114	na2hpo4	na2hpo4	PROPN
admet-425	54	115	,	,	PUNCT
admet-425	54	116	0.19	0.19	NUM
admet-425	54	117	g	g	PROPN
admet-425	54	118	kh2po4	kh2po4	NOUN
admet-425	54	119	,	,	PUNCT
admet-425	54	120	8	8	NUM
admet-425	54	121	g	g	NOUN
admet-425	54	122	nacl	nacl	NOUN
admet-425	54	123	and	and	CCONJ
admet-425	54	124	distilled	distil	VERB
admet-425	54	125	water	water	NOUN
admet-425	54	126	up	up	ADP
admet-425	54	127	to	to	ADP
admet-425	54	128	1000	1000	NUM
admet-425	54	129	ml	ml	ADP
admet-425	54	130	6.8	6.8	NUM
admet-425	54	131	[	[	X
admet-425	54	132	21	21	NUM
admet-425	54	133	]	]	X
admet-425	54	134	modified	modify	VERB
admet-425	54	135	simulated	simulate	VERB
admet-425	54	136	saliva	saliva	NOUN
admet-425	54	137	1.63	1.63	NUM
admet-425	54	138	g	g	PROPN
admet-425	54	139	kh2po4	kh2po4	NOUN
admet-425	54	140	,	,	PUNCT
admet-425	54	141	2.32	2.32	NUM
admet-425	54	142	g	g	PROPN
admet-425	54	143	nacl	nacl	NOUN
admet-425	54	144	,	,	PUNCT
admet-425	54	145	0.22	0.22	NUM
admet-425	54	146	g	g	NOUN
admet-425	54	147	cacl2	cacl2	NOUN
admet-425	54	148	and	and	CCONJ
admet-425	54	149	distilled	distil	VERB
admet-425	54	150	water	water	NOUN
admet-425	54	151	up	up	ADP
admet-425	54	152	to	to	ADP
admet-425	54	153	1000	1000	NUM
admet-425	54	154	ml	ml	ADP
admet-425	54	155	6.2	6.2	NUM
admet-425	54	156	[	[	SYM
admet-425	54	157	22	22	NUM
admet-425	54	158	]	]	X
admet-425	54	159	vaginal	vaginal	ADJ
admet-425	54	160	fluid	fluid	NOUN
admet-425	54	161	simulant	simulant	NOUN
admet-425	54	162	3.51	3.51	NUM
admet-425	54	163	g	g	NOUN
admet-425	54	164	nacl	nacl	NOUN
admet-425	54	165	,	,	PUNCT
admet-425	54	166	1.4	1.4	NUM
admet-425	54	167	g	g	PROPN
admet-425	54	168	koh	koh	PROPN
admet-425	54	169	,	,	PUNCT
admet-425	54	170	0.222	0.222	NUM
admet-425	54	171	g	g	PROPN
admet-425	54	172	ca(oh)2	ca(oh)2	NOUN
admet-425	54	173	,	,	PUNCT
admet-425	54	174	0.018	0.018	NUM
admet-425	54	175	g	g	PROPN
admet-425	54	176	bovine	bovine	NOUN
admet-425	54	177	serum	serum	NOUN
admet-425	54	178	albumin	albumin	NOUN
admet-425	54	179	,	,	PUNCT
admet-425	54	180	2	2	NUM
admet-425	54	181	g	g	NOUN
admet-425	54	182	lactic	lactic	ADJ
admet-425	54	183	acid	acid	NOUN
admet-425	54	184	,	,	PUNCT
admet-425	54	185	1	1	NUM
admet-425	54	186	g	g	NOUN
admet-425	54	187	acetic	acetic	ADJ
admet-425	54	188	acid	acid	NOUN
admet-425	54	189	,	,	PUNCT
admet-425	54	190	0.16	0.16	NUM
admet-425	54	191	g	g	PROPN
admet-425	54	192	glycerol	glycerol	NOUN
admet-425	54	193	,	,	PUNCT
admet-425	54	194	0.4	0.4	NUM
admet-425	54	195	g	g	PROPN
admet-425	54	196	urea	urea	NOUN
admet-425	54	197	,	,	PUNCT
admet-425	54	198	5	5	NUM
admet-425	54	199	g	g	NOUN
admet-425	54	200	glucose	glucose	NOUN
admet-425	54	201	and	and	CCONJ
admet-425	54	202	distilled	distil	VERB
admet-425	54	203	water	water	NOUN
admet-425	54	204	up	up	ADP
admet-425	54	205	to	to	ADP
admet-425	54	206	1000	1000	NUM
admet-425	54	207	ml	ml	ADP
admet-425	54	208	4.2	4.2	NUM
admet-425	55	1	[	[	X
admet-425	55	2	23	23	NUM
admet-425	55	3	]	]	X
admet-425	55	4	mario	mario	PROPN
admet-425	55	5	jug	jug	PROPN
admet-425	55	6	et	et	PROPN
admet-425	55	7	al	al	PROPN
admet-425	55	8	.	.	PROPN
admet-425	55	9	admet	admet	PROPN
admet-425	55	10	&	&	CCONJ
admet-425	55	11	dmpk	dmpk	PROPN
admet-425	55	12	5(3	5(3	NUM
admet-425	55	13	)	)	PUNCT
admet-425	55	14	(	(	PUNCT
admet-425	55	15	2017	2017	NUM
admet-425	55	16	)	)	PUNCT
admet-425	55	17	173	173	NUM
admet-425	55	18	-	-	SYM
admet-425	55	19	182	182	NUM
admet-425	55	20	176	176	NUM
admet-425	55	21	selection	selection	NOUN
admet-425	55	22	of	of	ADP
admet-425	55	23	the	the	DET
admet-425	55	24	apparatus	apparatus	NOUN
admet-425	55	25	type	type	NOUN
admet-425	55	26	and	and	CCONJ
admet-425	55	27	setup	setup	NOUN
admet-425	55	28	basket	basket	NOUN
admet-425	55	29	apparatus	apparatus	NOUN
admet-425	55	30	basket	basket	NOUN
admet-425	55	31	apparatus	apparatus	NOUN
admet-425	55	32	(	(	PUNCT
admet-425	55	33	apparatus	apparatus	NOUN
admet-425	55	34	1	1	NUM
admet-425	55	35	;	;	PUNCT
admet-425	55	36	figure	figure	NOUN
admet-425	55	37	1	1	NUM
admet-425	55	38	)	)	PUNCT
admet-425	55	39	has	have	AUX
admet-425	55	40	been	be	AUX
admet-425	55	41	applied	apply	VERB
admet-425	55	42	for	for	ADP
admet-425	55	43	the	the	DET
admet-425	55	44	in	in	ADV
admet-425	55	45	vitro	vitro	X
admet-425	55	46	release	release	NOUN
admet-425	55	47	testing	testing	NOUN
admet-425	55	48	of	of	ADP
admet-425	55	49	different	different	ADJ
admet-425	55	50	mucosal	mucosal	NOUN
admet-425	55	51	delivery	delivery	NOUN
admet-425	55	52	systems	system	NOUN
admet-425	55	53	,	,	PUNCT
admet-425	55	54	such	such	ADJ
admet-425	55	55	as	as	ADP
admet-425	55	56	nasal	nasal	ADJ
admet-425	55	57	microparticles	microparticle	NOUN
admet-425	55	58	[	[	X
admet-425	55	59	24	24	NUM
admet-425	55	60	]	]	PUNCT
admet-425	55	61	and	and	CCONJ
admet-425	55	62	inserts	insert	NOUN
admet-425	55	63	[	[	X
admet-425	55	64	25	25	NUM
admet-425	55	65	]	]	PUNCT
admet-425	55	66	using	use	VERB
admet-425	55	67	relatively	relatively	ADV
admet-425	55	68	large	large	ADJ
admet-425	55	69	volume	volume	NOUN
admet-425	55	70	(	(	PUNCT
admet-425	55	71	200	200	NUM
admet-425	55	72	-	-	SYM
admet-425	55	73	400	400	NUM
admet-425	55	74	ml	ml	NOUN
admet-425	55	75	)	)	PUNCT
admet-425	55	76	of	of	ADP
admet-425	55	77	the	the	DET
admet-425	55	78	dissolution	dissolution	ADJ
admet-425	55	79	medium	medium	ADJ
admet-425	55	80	and	and	CCONJ
admet-425	55	81	moderate	moderate	ADJ
admet-425	55	82	stirring	stirring	NOUN
admet-425	55	83	rate	rate	NOUN
admet-425	55	84	(	(	PUNCT
admet-425	55	85	50	50	NUM
admet-425	55	86	rpm	rpm	NOUN
admet-425	55	87	)	)	PUNCT
admet-425	55	88	.	.	PUNCT
admet-425	56	1	similar	similar	ADJ
admet-425	56	2	apparatus	apparatus	NOUN
admet-425	56	3	,	,	PUNCT
admet-425	56	4	operating	operate	VERB
admet-425	56	5	with	with	ADP
admet-425	56	6	250	250	NUM
admet-425	56	7	ml	ml	NOUN
admet-425	56	8	of	of	ADP
admet-425	56	9	the	the	DET
admet-425	56	10	simulated	simulate	VERB
admet-425	56	11	saliva	saliva	NOUN
admet-425	56	12	and	and	CCONJ
admet-425	56	13	50	50	NUM
admet-425	56	14	or	or	CCONJ
admet-425	56	15	100	100	NUM
admet-425	56	16	rpm	rpm	ADJ
admet-425	56	17	stirring	stirring	NOUN
admet-425	56	18	rate	rate	NOUN
admet-425	56	19	were	be	AUX
admet-425	56	20	used	use	VERB
admet-425	56	21	to	to	PART
admet-425	56	22	investigate	investigate	VERB
admet-425	56	23	the	the	DET
admet-425	56	24	release	release	NOUN
admet-425	56	25	of	of	ADP
admet-425	56	26	tizanidine	tizanidine	NOUN
admet-425	56	27	hydrochloride	hydrochloride	NOUN
admet-425	57	1	[	[	X
admet-425	57	2	26	26	NUM
admet-425	57	3	]	]	PUNCT
admet-425	57	4	and	and	CCONJ
admet-425	57	5	buspirone	buspirone	PROPN
admet-425	57	6	hydrochloride	hydrochloride	NOUN
admet-425	57	7	[	[	X
admet-425	57	8	27	27	NUM
admet-425	57	9	]	]	PUNCT
admet-425	57	10	from	from	ADP
admet-425	57	11	freeze	freeze	NOUN
admet-425	57	12	-	-	PUNCT
admet-425	57	13	dried	dry	VERB
admet-425	57	14	buccal	buccal	ADJ
admet-425	57	15	sponges	sponge	NOUN
admet-425	57	16	/	/	SYM
admet-425	57	17	wafers	wafer	NOUN
admet-425	57	18	.	.	PUNCT
admet-425	58	1	those	those	DET
admet-425	58	2	drugs	drug	NOUN
admet-425	58	3	are	be	AUX
admet-425	58	4	classified	classify	VERB
admet-425	58	5	as	as	ADP
admet-425	58	6	class	class	NOUN
admet-425	58	7	i	i	PRON
admet-425	58	8	drugs	drug	NOUN
admet-425	58	9	(	(	PUNCT
admet-425	58	10	high	high	ADJ
admet-425	58	11	solubility	solubility	NOUN
admet-425	58	12	and	and	CCONJ
admet-425	58	13	permeability	permeability	NOUN
admet-425	58	14	)	)	PUNCT
admet-425	58	15	according	accord	VERB
admet-425	58	16	to	to	ADP
admet-425	58	17	the	the	DET
admet-425	58	18	biopharmaceutical	biopharmaceutical	ADJ
admet-425	58	19	classification	classification	NOUN
admet-425	58	20	systems	system	NOUN
admet-425	58	21	(	(	PUNCT
admet-425	58	22	bcs	bcs	NOUN
admet-425	58	23	)	)	PUNCT
admet-425	58	24	and	and	CCONJ
admet-425	58	25	in	in	ADP
admet-425	58	26	both	both	DET
admet-425	58	27	cases	case	NOUN
admet-425	58	28	,	,	PUNCT
admet-425	58	29	level	level	VERB
admet-425	58	30	a	a	PRON
admet-425	58	31	of	of	ADP
admet-425	58	32	ivivc	ivivc	NOUN
admet-425	58	33	was	be	AUX
admet-425	58	34	obtained	obtain	VERB
admet-425	58	35	by	by	ADP
admet-425	58	36	such	such	ADJ
admet-425	58	37	instrumental	instrumental	ADJ
admet-425	58	38	setup	setup	NOUN
admet-425	58	39	[	[	X
admet-425	58	40	26,27	26,27	NUM
admet-425	58	41	]	]	PUNCT
admet-425	58	42	.	.	PUNCT
admet-425	59	1	basket	basket	NOUN
admet-425	59	2	apparatus	apparatus	NOUN
admet-425	59	3	has	have	AUX
admet-425	59	4	been	be	AUX
admet-425	59	5	also	also	ADV
admet-425	59	6	applied	apply	VERB
admet-425	59	7	for	for	ADP
admet-425	59	8	the	the	DET
admet-425	59	9	in	in	X
admet-425	59	10	vitro	vitro	X
admet-425	59	11	drug	drug	NOUN
admet-425	59	12	release	release	NOUN
admet-425	59	13	testing	testing	NOUN
admet-425	59	14	of	of	ADP
admet-425	59	15	both	both	CCONJ
admet-425	59	16	solid	solid	ADJ
admet-425	59	17	and	and	CCONJ
admet-425	59	18	in	in	ADP
admet-425	59	19	situ	situ	ADJ
admet-425	59	20	gelling	gel	VERB
admet-425	59	21	rectal	rectal	ADJ
admet-425	59	22	suppositories	suppository	NOUN
admet-425	59	23	.	.	PUNCT
admet-425	60	1	in	in	ADP
admet-425	60	2	latter	latter	ADJ
admet-425	60	3	case	case	NOUN
admet-425	60	4	,	,	PUNCT
admet-425	60	5	the	the	DET
admet-425	60	6	formulation	formulation	NOUN
admet-425	60	7	was	be	AUX
admet-425	60	8	first	first	ADV
admet-425	60	9	thermostated	thermostat	VERB
admet-425	60	10	at	at	ADP
admet-425	60	11	37	37	NUM
admet-425	60	12	°	°	NOUN
admet-425	60	13	c	c	NOUN
admet-425	60	14	in	in	ADP
admet-425	60	15	suppository	suppository	ADJ
admet-425	60	16	moulds	mould	NOUN
admet-425	60	17	to	to	PART
admet-425	60	18	achieve	achieve	VERB
admet-425	60	19	solidification	solidification	NOUN
admet-425	60	20	of	of	ADP
admet-425	60	21	the	the	DET
admet-425	60	22	formulation	formulation	NOUN
admet-425	60	23	prior	prior	ADV
admet-425	60	24	its	its	PRON
admet-425	60	25	placing	placing	NOUN
admet-425	60	26	into	into	ADP
admet-425	60	27	basket	basket	NOUN
admet-425	60	28	[	[	X
admet-425	60	29	28	28	NUM
admet-425	60	30	]	]	PUNCT
admet-425	60	31	.	.	PUNCT
admet-425	61	1	another	another	DET
admet-425	61	2	approach	approach	NOUN
admet-425	61	3	,	,	PUNCT
admet-425	61	4	where	where	SCONJ
admet-425	61	5	a	a	DET
admet-425	61	6	liquid	liquid	ADJ
admet-425	61	7	suppository	suppository	ADJ
admet-425	61	8	formulation	formulation	NOUN
admet-425	61	9	was	be	AUX
admet-425	61	10	directly	directly	ADV
admet-425	61	11	introduced	introduce	VERB
admet-425	61	12	into	into	ADP
admet-425	61	13	the	the	DET
admet-425	61	14	basket	basket	NOUN
admet-425	61	15	covered	cover	VERB
admet-425	61	16	with	with	ADP
admet-425	61	17	gauze	gauze	NOUN
admet-425	61	18	,	,	PUNCT
admet-425	61	19	was	be	AUX
admet-425	61	20	also	also	ADV
admet-425	61	21	described	describe	VERB
admet-425	61	22	[	[	X
admet-425	61	23	29	29	NUM
admet-425	61	24	]	]	PUNCT
admet-425	61	25	.	.	PUNCT
admet-425	62	1	compendial	compendial	ADJ
admet-425	62	2	monographs	monograph	NOUN
admet-425	62	3	,	,	PUNCT
admet-425	62	4	usp	usp	NOUN
admet-425	62	5	dissolution	dissolution	NOUN
admet-425	62	6	database	database	NOUN
admet-425	62	7	and	and	CCONJ
admet-425	62	8	fda	fda	PROPN
admet-425	62	9	dissolution	dissolution	PROPN
admet-425	62	10	database	database	NOUN
admet-425	62	11	also	also	ADV
admet-425	62	12	recommend	recommend	VERB
admet-425	62	13	the	the	DET
admet-425	62	14	use	use	NOUN
admet-425	62	15	of	of	ADP
admet-425	62	16	basket	basket	NOUN
admet-425	62	17	apparatus	apparatus	NOUN
admet-425	62	18	,	,	PUNCT
admet-425	62	19	both	both	PRON
admet-425	62	20	in	in	ADP
admet-425	62	21	standard	standard	NOUN
admet-425	62	22	and	and	CCONJ
admet-425	62	23	the	the	DET
admet-425	62	24	small	small	ADJ
admet-425	62	25	-	-	PUNCT
admet-425	62	26	volume	volume	NOUN
admet-425	62	27	configuration	configuration	NOUN
admet-425	62	28	,	,	PUNCT
admet-425	62	29	for	for	ADP
admet-425	62	30	the	the	DET
admet-425	62	31	in	in	X
admet-425	62	32	vitro	vitro	X
admet-425	62	33	testing	testing	NOUN
admet-425	62	34	of	of	ADP
admet-425	62	35	mucosal	mucosal	NOUN
admet-425	62	36	delivery	delivery	NOUN
admet-425	62	37	systems	system	NOUN
admet-425	62	38	(	(	PUNCT
admet-425	62	39	table	table	NOUN
admet-425	62	40	1	1	NUM
admet-425	62	41	)	)	PUNCT
admet-425	62	42	.	.	PUNCT
admet-425	62	43	.	.	PUNCT
admet-425	63	1	figure	figure	VERB
admet-425	63	2	1	1	NUM
admet-425	63	3	.	.	PUNCT
admet-425	64	1	schematic	schematic	ADJ
admet-425	64	2	representation	representation	NOUN
admet-425	64	3	of	of	ADP
admet-425	64	4	the	the	DET
admet-425	64	5	basket	basket	NOUN
admet-425	64	6	apparatus	apparatus	NOUN
admet-425	64	7	(	(	PUNCT
admet-425	64	8	apparatus	apparatus	NOUN
admet-425	64	9	1	1	NUM
admet-425	64	10	)	)	PUNCT
admet-425	64	11	.	.	PUNCT
admet-425	65	1	reprinted	reprint	VERB
admet-425	65	2	from	from	ADP
admet-425	65	3	ref	ref	NOUN
admet-425	65	4	.	.	PUNCT
admet-425	66	1	[	[	X
admet-425	66	2	3	3	X
admet-425	66	3	]	]	PUNCT
admet-425	66	4	with	with	ADP
admet-425	66	5	permission	permission	NOUN
admet-425	66	6	of	of	ADP
admet-425	66	7	elsevier	elsevier	PROPN
admet-425	66	8	.	.	PUNCT
admet-425	67	1	paddle	paddle	PROPN
admet-425	67	2	apparatus	apparatus	PROPN
admet-425	67	3	and	and	CCONJ
admet-425	67	4	modifications	modification	NOUN
admet-425	67	5	conventional	conventional	ADJ
admet-425	67	6	paddle	paddle	NOUN
admet-425	67	7	apparatus	apparatus	NOUN
admet-425	67	8	(	(	PUNCT
admet-425	67	9	apparatus	apparatus	NOUN
admet-425	67	10	2	2	NUM
admet-425	67	11	;	;	PUNCT
admet-425	67	12	figure	figure	NOUN
admet-425	67	13	2a	2a	NUM
admet-425	67	14	)	)	PUNCT
admet-425	67	15	with	with	ADP
admet-425	67	16	900	900	NUM
admet-425	67	17	ml	ml	NOUN
admet-425	67	18	of	of	ADP
admet-425	67	19	the	the	DET
admet-425	67	20	dissolution	dissolution	NOUN
admet-425	67	21	media	medium	NOUN
admet-425	67	22	stirred	stir	VERB
admet-425	67	23	at	at	ADP
admet-425	67	24	50	50	NUM
admet-425	67	25	rpm	rpm	NOUN
admet-425	67	26	has	have	AUX
admet-425	67	27	been	be	AUX
admet-425	67	28	occasionally	occasionally	ADV
admet-425	67	29	used	use	VERB
admet-425	67	30	for	for	ADP
admet-425	67	31	the	the	DET
admet-425	67	32	in	in	ADV
admet-425	67	33	vitro	vitro	X
admet-425	67	34	release	release	NOUN
admet-425	67	35	testing	testing	NOUN
admet-425	67	36	from	from	ADP
admet-425	67	37	buccal	buccal	ADJ
admet-425	67	38	tablets	tablet	NOUN
admet-425	67	39	[	[	X
admet-425	67	40	30	30	NUM
admet-425	67	41	]	]	PUNCT
admet-425	67	42	,	,	PUNCT
admet-425	67	43	sublingual	sublingual	ADJ
admet-425	67	44	formulations	formulation	NOUN
admet-425	67	45	[	[	X
admet-425	67	46	31	31	NUM
admet-425	67	47	]	]	PUNCT
admet-425	67	48	,	,	PUNCT
admet-425	67	49	vaginal	vaginal	ADJ
admet-425	67	50	tablets	tablet	NOUN
admet-425	67	51	[	[	X
admet-425	67	52	32	32	NUM
admet-425	67	53	]	]	PUNCT
admet-425	67	54	and	and	CCONJ
admet-425	67	55	self	self	NOUN
admet-425	67	56	-	-	PUNCT
admet-425	67	57	microemulsifying	microemulsifye	VERB
admet-425	67	58	rectal	rectal	ADJ
admet-425	67	59	suppositories	suppository	NOUN
admet-425	67	60	[	[	X
admet-425	67	61	33	33	NUM
admet-425	67	62	]	]	PUNCT
admet-425	67	63	.	.	PUNCT
admet-425	68	1	according	accord	VERB
admet-425	68	2	to	to	ADP
admet-425	68	3	the	the	DET
admet-425	68	4	monographs	monograph	NOUN
admet-425	68	5	and	and	CCONJ
admet-425	68	6	methods	method	NOUN
admet-425	68	7	published	publish	VERB
admet-425	68	8	by	by	ADP
admet-425	68	9	usp	usp	PROPN
admet-425	68	10	,	,	PUNCT
admet-425	68	11	ph	ph	PROPN
admet-425	68	12	.	.	PROPN
admet-425	68	13	eur	eur	PROPN
admet-425	68	14	.	.	PUNCT
admet-425	69	1	and	and	CCONJ
admet-425	69	2	fda	fda	PROPN
admet-425	69	3	(	(	PUNCT
admet-425	69	4	table	table	NOUN
admet-425	69	5	1	1	NUM
admet-425	69	6	)	)	PUNCT
admet-425	69	7	,	,	PUNCT
admet-425	69	8	the	the	DET
admet-425	69	9	paddle	paddle	NOUN
admet-425	69	10	apparatus	apparatus	NOUN
admet-425	69	11	is	be	AUX
admet-425	69	12	used	use	VERB
admet-425	69	13	for	for	ADP
admet-425	69	14	a	a	DET
admet-425	69	15	variety	variety	NOUN
admet-425	69	16	of	of	ADP
admet-425	69	17	mucosal	mucosal	ADJ
admet-425	69	18	drug	drug	NOUN
admet-425	69	19	delivery	delivery	NOUN
admet-425	69	20	systems	system	NOUN
admet-425	69	21	.	.	PUNCT
admet-425	70	1	however	however	ADV
admet-425	70	2	,	,	PUNCT
admet-425	70	3	the	the	DET
admet-425	70	4	general	general	ADJ
admet-425	70	5	intention	intention	NOUN
admet-425	70	6	of	of	ADP
admet-425	70	7	the	the	DET
admet-425	70	8	researchers	researcher	NOUN
admet-425	70	9	in	in	ADP
admet-425	70	10	the	the	DET
admet-425	70	11	field	field	NOUN
admet-425	70	12	is	be	AUX
admet-425	70	13	to	to	PART
admet-425	70	14	reduce	reduce	VERB
admet-425	70	15	the	the	DET
admet-425	70	16	volume	volume	NOUN
admet-425	70	17	of	of	ADP
admet-425	70	18	the	the	DET
admet-425	70	19	dissolution	dissolution	PROPN
admet-425	70	20	medium	medium	NOUN
admet-425	70	21	applied	apply	VERB
admet-425	70	22	[	[	X
admet-425	70	23	34,35	34,35	NOUN
admet-425	70	24	]	]	PUNCT
admet-425	70	25	.	.	PUNCT
admet-425	71	1	in	in	ADP
admet-425	71	2	cases	case	NOUN
admet-425	71	3	where	where	SCONJ
admet-425	71	4	the	the	DET
admet-425	71	5	volume	volume	NOUN
admet-425	71	6	is	be	AUX
admet-425	71	7	significantly	significantly	ADV
admet-425	71	8	reduced	reduce	VERB
admet-425	71	9	to	to	ADP
admet-425	71	10	only	only	ADV
admet-425	71	11	10	10	NUM
admet-425	71	12	-	-	SYM
admet-425	71	13	25	25	NUM
admet-425	71	14	ml	ml	NOUN
admet-425	71	15	,	,	PUNCT
admet-425	71	16	the	the	DET
admet-425	71	17	agitation	agitation	NOUN
admet-425	71	18	is	be	AUX
admet-425	71	19	performed	perform	VERB
admet-425	71	20	by	by	ADP
admet-425	71	21	the	the	DET
admet-425	71	22	use	use	NOUN
admet-425	71	23	of	of	ADP
admet-425	71	24	shaking	shake	VERB
admet-425	71	25	incubators	incubator	NOUN
admet-425	71	26	.	.	PUNCT
admet-425	72	1	using	use	VERB
admet-425	72	2	such	such	ADJ
admet-425	72	3	apparatus	apparatus	NOUN
admet-425	72	4	,	,	PUNCT
admet-425	72	5	level	level	VERB
admet-425	72	6	a	a	DET
admet-425	72	7	ivivc	ivivc	NOUN
admet-425	72	8	with	with	ADP
admet-425	72	9	correlation	correlation	NOUN
admet-425	72	10	coefficient	coefficient	NOUN
admet-425	72	11	of	of	ADP
admet-425	72	12	0.909	0.909	NUM
admet-425	72	13	was	be	AUX
admet-425	72	14	obtained	obtain	VERB
admet-425	72	15	for	for	ADP
admet-425	72	16	carbamazepine	carbamazepine	NOUN
admet-425	72	17	release	release	NOUN
admet-425	72	18	from	from	ADP
admet-425	72	19	buccal	buccal	ADJ
admet-425	72	20	multi	multi	ADJ
admet-425	72	21	-	-	ADJ
admet-425	72	22	composite	composite	ADJ
admet-425	72	23	constructs	construct	NOUN
admet-425	73	1	[	[	X
admet-425	73	2	34	34	NUM
admet-425	73	3	]	]	PUNCT
admet-425	73	4	.	.	PUNCT
admet-425	74	1	the	the	DET
admet-425	74	2	same	same	ADJ
admet-425	74	3	level	level	NOUN
admet-425	74	4	of	of	ADP
admet-425	74	5	ivivc	ivivc	NOUN
admet-425	74	6	was	be	AUX
admet-425	74	7	obtained	obtain	VERB
admet-425	74	8	in	in	ADP
admet-425	74	9	the	the	DET
admet-425	74	10	case	case	NOUN
admet-425	74	11	of	of	ADP
admet-425	74	12	vaginal	vaginal	ADJ
admet-425	74	13	nuvaring	nuvaring	ADJ
admet-425	74	14	®	®	NOUN
admet-425	74	15	,	,	PUNCT
admet-425	74	16	using	use	VERB
admet-425	74	17	similar	similar	ADJ
admet-425	74	18	approach	approach	NOUN
admet-425	74	19	[	[	X
admet-425	74	20	36	36	NUM
admet-425	74	21	]	]	PUNCT
admet-425	74	22	.	.	PUNCT
admet-425	75	1	while	while	SCONJ
admet-425	75	2	analysing	analyse	VERB
admet-425	75	3	the	the	DET
admet-425	75	4	in	in	ADV
admet-425	75	5	vitro	vitro	X
admet-425	75	6	release	release	NOUN
admet-425	75	7	of	of	ADP
admet-425	75	8	buccal	buccal	ADJ
admet-425	75	9	and	and	CCONJ
admet-425	75	10	sublingual	sublingual	ADJ
admet-425	75	11	films	film	NOUN
admet-425	75	12	by	by	ADP
admet-425	75	13	paddle	paddle	NOUN
admet-425	75	14	apparatus	apparatus	NOUN
admet-425	75	15	,	,	PUNCT
admet-425	75	16	a	a	DET
admet-425	75	17	formulation	formulation	NOUN
admet-425	75	18	is	be	AUX
admet-425	75	19	commonly	commonly	ADV
admet-425	75	20	attached	attach	VERB
admet-425	75	21	to	to	ADP
admet-425	75	22	a	a	DET
admet-425	75	23	glass	glass	NOUN
admet-425	75	24	slide	slide	NOUN
admet-425	75	25	with	with	ADP
admet-425	75	26	cyanoacrylate	cyanoacrylate	NOUN
admet-425	75	27	glue	glue	NOUN
admet-425	75	28	[	[	X
admet-425	75	29	37	37	NUM
admet-425	75	30	]	]	PUNCT
admet-425	75	31	or	or	CCONJ
admet-425	75	32	two	two	NUM
admet-425	75	33	sided	sided	ADJ
admet-425	75	34	adhesive	adhesive	ADJ
admet-425	75	35	tape	tape	NOUN
admet-425	76	1	[	[	X
admet-425	76	2	38	38	NUM
admet-425	76	3	]	]	PUNCT
admet-425	76	4	and	and	CCONJ
admet-425	76	5	then	then	ADV
admet-425	76	6	immersed	immerse	VERB
admet-425	76	7	into	into	ADP
admet-425	76	8	dissolution	dissolution	ADJ
admet-425	76	9	vessel	vessel	NOUN
admet-425	76	10	or	or	CCONJ
admet-425	76	11	glued	glue	VERB
admet-425	76	12	onto	onto	ADP
admet-425	76	13	the	the	DET
admet-425	76	14	inner	inner	ADJ
admet-425	76	15	side	side	NOUN
admet-425	76	16	of	of	ADP
admet-425	76	17	the	the	DET
admet-425	76	18	dissolution	dissolution	ADJ
admet-425	76	19	vessel	vessel	NOUN
admet-425	77	1	[	[	X
admet-425	77	2	37	37	NUM
admet-425	77	3	]	]	PUNCT
admet-425	77	4	.	.	PUNCT
admet-425	78	1	considering	consider	VERB
admet-425	78	2	the	the	DET
admet-425	78	3	porosity	porosity	NOUN
admet-425	78	4	and	and	CCONJ
admet-425	78	5	the	the	DET
admet-425	78	6	thickness	thickness	NOUN
admet-425	78	7	of	of	ADP
admet-425	78	8	the	the	DET
admet-425	78	9	formulation	formulation	NOUN
admet-425	78	10	,	,	PUNCT
admet-425	78	11	the	the	DET
admet-425	78	12	permeation	permeation	NOUN
admet-425	78	13	of	of	ADP
admet-425	78	14	admet	admet	PROPN
admet-425	78	15	&	&	CCONJ
admet-425	78	16	dmpk	dmpk	PROPN
admet-425	78	17	5(3	5(3	NUM
admet-425	78	18	)	)	PUNCT
admet-425	78	19	(	(	PUNCT
admet-425	78	20	2017	2017	NUM
admet-425	78	21	)	)	PUNCT
admet-425	78	22	173	173	NUM
admet-425	78	23	-	-	SYM
admet-425	78	24	182	182	NUM
admet-425	78	25	in	in	ADP
admet-425	78	26	vitro	vitro	X
admet-425	78	27	release	release	NOUN
admet-425	78	28	testing	testing	NOUN
admet-425	78	29	of	of	ADP
admet-425	78	30	mucosal	mucosal	ADJ
admet-425	78	31	drug	drug	NOUN
admet-425	78	32	delivery	delivery	NOUN
admet-425	78	33	systems	system	NOUN
admet-425	78	34	doi	doi	NOUN
admet-425	78	35	:	:	PUNCT
admet-425	78	36	10.5599	10.5599	NUM
admet-425	78	37	/	/	SYM
admet-425	78	38	admet.5.3.425	admet.5.3.425	NUM
admet-425	78	39	177	177	NUM
admet-425	78	40	the	the	DET
admet-425	78	41	glue	glue	NOUN
admet-425	78	42	into	into	ADP
admet-425	78	43	the	the	DET
admet-425	78	44	formulation	formulation	NOUN
admet-425	78	45	could	could	AUX
admet-425	78	46	be	be	AUX
admet-425	78	47	presumed	presume	VERB
admet-425	78	48	with	with	ADP
admet-425	78	49	consequent	consequent	ADJ
admet-425	78	50	modification	modification	NOUN
admet-425	78	51	of	of	ADP
admet-425	78	52	the	the	DET
admet-425	78	53	drug	drug	NOUN
admet-425	78	54	release	release	NOUN
admet-425	78	55	process	process	NOUN
admet-425	78	56	.	.	PUNCT
admet-425	79	1	in	in	ADP
admet-425	79	2	this	this	DET
admet-425	79	3	regard	regard	NOUN
admet-425	79	4	,	,	PUNCT
admet-425	79	5	the	the	DET
admet-425	79	6	use	use	NOUN
admet-425	79	7	of	of	ADP
admet-425	79	8	metal	metal	NOUN
admet-425	79	9	clamps	clamp	NOUN
admet-425	79	10	,	,	PUNCT
admet-425	79	11	supports	support	VERB
admet-425	79	12	with	with	ADP
admet-425	79	13	wire	wire	NOUN
admet-425	79	14	mesh	mesh	NOUN
admet-425	79	15	or	or	CCONJ
admet-425	79	16	compendial	compendial	ADJ
admet-425	79	17	apparatus	apparatus	NOUN
admet-425	79	18	5	5	NUM
admet-425	79	19	(	(	PUNCT
admet-425	79	20	paddle	paddle	NOUN
admet-425	79	21	over	over	ADP
admet-425	79	22	disc	disc	NOUN
admet-425	79	23	,	,	PUNCT
admet-425	79	24	figure	figure	NOUN
admet-425	79	25	2b	2b	NOUN
admet-425	79	26	)	)	PUNCT
admet-425	79	27	is	be	AUX
admet-425	79	28	preferred	prefer	VERB
admet-425	79	29	.	.	PUNCT
admet-425	80	1	furthermore	furthermore	ADV
admet-425	80	2	,	,	PUNCT
admet-425	80	3	the	the	DET
admet-425	80	4	position	position	NOUN
admet-425	80	5	of	of	ADP
admet-425	80	6	the	the	DET
admet-425	80	7	formulation	formulation	NOUN
admet-425	80	8	(	(	PUNCT
admet-425	80	9	bottom	bottom	NOUN
admet-425	80	10	or	or	CCONJ
admet-425	80	11	the	the	DET
admet-425	80	12	side	side	NOUN
admet-425	80	13	of	of	ADP
admet-425	80	14	the	the	DET
admet-425	80	15	dissolution	dissolution	ADJ
admet-425	80	16	vessel	vessel	NOUN
admet-425	80	17	)	)	PUNCT
admet-425	80	18	influences	influence	VERB
admet-425	80	19	greatly	greatly	ADV
admet-425	80	20	on	on	ADP
admet-425	80	21	the	the	DET
admet-425	80	22	observed	observe	VERB
admet-425	80	23	in	in	ADP
admet-425	80	24	vitro	vitro	X
admet-425	80	25	drug	drug	NOUN
admet-425	80	26	release	release	NOUN
admet-425	80	27	kinetic	kinetic	NOUN
admet-425	80	28	,	,	PUNCT
admet-425	80	29	due	due	ADP
admet-425	80	30	to	to	ADP
admet-425	80	31	differences	difference	NOUN
admet-425	80	32	in	in	ADP
admet-425	80	33	hydrodynamics	hydrodynamic	NOUN
admet-425	80	34	inside	inside	ADP
admet-425	80	35	the	the	DET
admet-425	80	36	dissolution	dissolution	NOUN
admet-425	80	37	vessel	vessel	NOUN
admet-425	80	38	[	[	X
admet-425	80	39	37	37	NUM
admet-425	80	40	]	]	PUNCT
admet-425	80	41	.	.	PUNCT
admet-425	81	1	(	(	PUNCT
admet-425	81	2	a	a	X
admet-425	81	3	)	)	PUNCT
admet-425	81	4	(	(	PUNCT
admet-425	81	5	b	b	X
admet-425	81	6	)	)	PUNCT
admet-425	81	7	(	(	PUNCT
admet-425	81	8	c	c	X
admet-425	81	9	)	)	PUNCT
admet-425	81	10	figure	figure	NOUN
admet-425	81	11	2	2	NUM
admet-425	81	12	.	.	PUNCT
admet-425	81	13	schematic	schematic	ADJ
admet-425	81	14	representation	representation	NOUN
admet-425	81	15	of	of	ADP
admet-425	81	16	the	the	DET
admet-425	81	17	paddle	paddle	NOUN
admet-425	81	18	apparatus	apparatus	NOUN
admet-425	81	19	(	(	PUNCT
admet-425	81	20	a	a	X
admet-425	81	21	)	)	PUNCT
admet-425	81	22	,	,	PUNCT
admet-425	81	23	paddle	paddle	NOUN
admet-425	81	24	over	over	ADP
admet-425	81	25	disc	disc	NOUN
admet-425	81	26	apparatus	apparatus	NOUN
admet-425	81	27	(	(	PUNCT
admet-425	81	28	b	b	NOUN
admet-425	81	29	)	)	PUNCT
admet-425	81	30	and	and	CCONJ
admet-425	81	31	immersion	immersion	NOUN
admet-425	81	32	cell	cell	NOUN
admet-425	81	33	in	in	ADP
admet-425	81	34	combination	combination	NOUN
admet-425	81	35	with	with	ADP
admet-425	81	36	the	the	DET
admet-425	81	37	small	small	ADJ
admet-425	81	38	-	-	PUNCT
admet-425	81	39	volume	volume	NOUN
admet-425	81	40	paddle	paddle	NOUN
admet-425	81	41	apparatus	apparatus	NOUN
admet-425	81	42	(	(	PUNCT
admet-425	81	43	c	c	NOUN
admet-425	81	44	)	)	PUNCT
admet-425	81	45	.	.	PUNCT
admet-425	82	1	reprinted	reprint	VERB
admet-425	82	2	from	from	ADP
admet-425	82	3	ref	ref	NOUN
admet-425	82	4	.	.	PUNCT
admet-425	83	1	[	[	X
admet-425	83	2	3	3	X
admet-425	83	3	]	]	PUNCT
admet-425	83	4	with	with	ADP
admet-425	83	5	permission	permission	NOUN
admet-425	83	6	of	of	ADP
admet-425	83	7	elsevier	elsevier	NOUN
admet-425	83	8	.	.	PUNCT
admet-425	84	1	membrane	membrane	NOUN
admet-425	84	2	diffusion	diffusion	NOUN
admet-425	84	3	methods	method	NOUN
admet-425	84	4	membrane	membrane	NOUN
admet-425	84	5	diffusion	diffusion	NOUN
admet-425	84	6	(	(	PUNCT
admet-425	84	7	i.e.	i.e.	X
admet-425	84	8	dialysis	dialysis	NOUN
admet-425	84	9	)	)	PUNCT
admet-425	84	10	method	method	NOUN
admet-425	84	11	is	be	AUX
admet-425	84	12	considered	consider	VERB
admet-425	84	13	as	as	ADP
admet-425	84	14	one	one	NUM
admet-425	84	15	of	of	ADP
admet-425	84	16	the	the	DET
admet-425	84	17	most	most	ADV
admet-425	84	18	convenient	convenient	ADJ
admet-425	84	19	techniques	technique	NOUN
admet-425	84	20	for	for	ADP
admet-425	84	21	determining	determine	VERB
admet-425	84	22	the	the	DET
admet-425	84	23	drug	drug	NOUN
admet-425	84	24	release	release	NOUN
admet-425	84	25	profiles	profile	NOUN
admet-425	84	26	of	of	ADP
admet-425	84	27	nano	nano	NOUN
admet-425	84	28	-	-	PUNCT
admet-425	84	29	sized	sized	ADJ
admet-425	84	30	drug	drug	NOUN
admet-425	84	31	delivery	delivery	NOUN
admet-425	84	32	systems	system	NOUN
admet-425	84	33	like	like	ADP
admet-425	84	34	nanoparticles	nanoparticle	NOUN
admet-425	84	35	,	,	PUNCT
admet-425	84	36	liposomes	liposome	NOUN
admet-425	84	37	,	,	PUNCT
admet-425	84	38	nanosuspensions	nanosuspension	NOUN
admet-425	84	39	and	and	CCONJ
admet-425	84	40	emulsions	emulsion	NOUN
admet-425	84	41	[	[	X
admet-425	84	42	3,39	3,39	NOUN
admet-425	84	43	]	]	PUNCT
admet-425	84	44	.	.	PUNCT
admet-425	85	1	the	the	DET
admet-425	85	2	most	most	ADV
admet-425	85	3	commonly	commonly	ADV
admet-425	85	4	used	use	VERB
admet-425	85	5	setups	setup	NOUN
admet-425	85	6	are	be	AUX
admet-425	85	7	dialysis	dialysis	NOUN
admet-425	85	8	bag	bag	NOUN
admet-425	85	9	,	,	PUNCT
admet-425	85	10	flow	flow	NOUN
admet-425	85	11	-	-	PUNCT
admet-425	85	12	through	through	ADP
admet-425	85	13	apparatus	apparatus	NOUN
admet-425	85	14	(	(	PUNCT
admet-425	85	15	with	with	ADP
admet-425	85	16	a	a	DET
admet-425	85	17	membrane	membrane	NOUN
admet-425	85	18	-	-	PUNCT
admet-425	85	19	containing	contain	VERB
admet-425	85	20	adapter	adapter	NOUN
admet-425	85	21	)	)	PUNCT
admet-425	85	22	,	,	PUNCT
admet-425	85	23	franz	franz	NOUN
admet-425	85	24	-	-	PUNCT
admet-425	85	25	diffusion	diffusion	NOUN
admet-425	85	26	cell	cell	NOUN
admet-425	85	27	and	and	CCONJ
admet-425	85	28	immersion	immersion	NOUN
admet-425	85	29	cell	cell	NOUN
admet-425	85	30	.	.	PUNCT
admet-425	86	1	the	the	DET
admet-425	86	2	advantages	advantage	NOUN
admet-425	86	3	of	of	ADP
admet-425	86	4	dialysis	dialysis	NOUN
admet-425	86	5	over	over	ADP
admet-425	86	6	other	other	ADJ
admet-425	86	7	methods	method	NOUN
admet-425	86	8	are	be	AUX
admet-425	86	9	in	in	ADP
admet-425	86	10	the	the	DET
admet-425	86	11	ease	ease	NOUN
admet-425	86	12	of	of	ADP
admet-425	86	13	sampling	sampling	NOUN
admet-425	86	14	and	and	CCONJ
admet-425	86	15	replacement	replacement	NOUN
admet-425	86	16	of	of	ADP
admet-425	86	17	receptor	receptor	NOUN
admet-425	86	18	media	medium	NOUN
admet-425	86	19	due	due	ADP
admet-425	86	20	to	to	ADP
admet-425	86	21	the	the	DET
admet-425	86	22	physical	physical	ADJ
admet-425	86	23	separation	separation	NOUN
admet-425	86	24	of	of	ADP
admet-425	86	25	the	the	DET
admet-425	86	26	formulation	formulation	NOUN
admet-425	86	27	(	(	PUNCT
admet-425	86	28	by	by	ADP
admet-425	86	29	semipermeable	semipermeable	ADJ
admet-425	86	30	dialysis	dialysis	NOUN
admet-425	86	31	membrane	membrane	NOUN
admet-425	86	32	)	)	PUNCT
admet-425	86	33	from	from	ADP
admet-425	86	34	the	the	DET
admet-425	86	35	receptor	receptor	NOUN
admet-425	86	36	media	medium	NOUN
admet-425	86	37	.	.	PUNCT
admet-425	87	1	however	however	ADV
admet-425	87	2	,	,	PUNCT
admet-425	87	3	it	it	PRON
admet-425	87	4	is	be	AUX
admet-425	87	5	important	important	ADJ
admet-425	87	6	to	to	PART
admet-425	87	7	emphasize	emphasize	VERB
admet-425	87	8	that	that	SCONJ
admet-425	87	9	non	non	ADJ
admet-425	87	10	-	-	ADJ
admet-425	87	11	critical	critical	ADJ
admet-425	87	12	interpretation	interpretation	NOUN
admet-425	87	13	of	of	ADP
admet-425	87	14	the	the	DET
admet-425	87	15	obtained	obtain	VERB
admet-425	87	16	results	result	NOUN
admet-425	87	17	can	can	AUX
admet-425	87	18	lead	lead	VERB
admet-425	87	19	to	to	AUX
admet-425	87	20	flawed	flaw	VERB
admet-425	87	21	conclusions	conclusion	NOUN
admet-425	87	22	about	about	ADP
admet-425	87	23	the	the	DET
admet-425	87	24	kinetics	kinetic	NOUN
admet-425	87	25	of	of	ADP
admet-425	87	26	drug	drug	NOUN
admet-425	87	27	release	release	NOUN
admet-425	87	28	from	from	ADP
admet-425	87	29	the	the	DET
admet-425	87	30	colloidal	colloidal	NOUN
admet-425	87	31	carriers	carrier	NOUN
admet-425	87	32	[	[	X
admet-425	87	33	40,41	40,41	X
admet-425	87	34	]	]	X
admet-425	87	35	and	and	CCONJ
admet-425	87	36	other	other	ADJ
admet-425	87	37	formulation	formulation	NOUN
admet-425	87	38	types	type	NOUN
admet-425	87	39	[	[	X
admet-425	87	40	42–46	42–46	NUM
admet-425	87	41	]	]	PUNCT
admet-425	87	42	.	.	PUNCT
admet-425	88	1	the	the	DET
admet-425	88	2	presence	presence	NOUN
admet-425	88	3	of	of	ADP
admet-425	88	4	the	the	DET
admet-425	88	5	drug	drug	NOUN
admet-425	88	6	in	in	ADP
admet-425	88	7	the	the	DET
admet-425	88	8	receptor	receptor	NOUN
admet-425	88	9	medium	medium	NOUN
admet-425	88	10	is	be	AUX
admet-425	88	11	the	the	DET
admet-425	88	12	result	result	NOUN
admet-425	88	13	of	of	ADP
admet-425	88	14	drug	drug	NOUN
admet-425	88	15	release	release	NOUN
admet-425	88	16	from	from	ADP
admet-425	88	17	the	the	DET
admet-425	88	18	carrier	carrier	NOUN
admet-425	88	19	to	to	ADP
admet-425	88	20	the	the	DET
admet-425	88	21	continuous	continuous	ADJ
admet-425	88	22	phase	phase	NOUN
admet-425	88	23	in	in	ADP
admet-425	88	24	the	the	DET
admet-425	88	25	donor	donor	NOUN
admet-425	88	26	compartment	compartment	NOUN
admet-425	88	27	and	and	CCONJ
admet-425	88	28	diffusion	diffusion	NOUN
admet-425	88	29	of	of	ADP
admet-425	88	30	the	the	DET
admet-425	88	31	drug	drug	NOUN
admet-425	88	32	through	through	ADP
admet-425	88	33	the	the	DET
admet-425	88	34	membrane	membrane	NOUN
admet-425	88	35	from	from	ADP
admet-425	88	36	the	the	DET
admet-425	88	37	donor	donor	NOUN
admet-425	88	38	to	to	ADP
admet-425	88	39	the	the	DET
admet-425	88	40	receptor	receptor	NOUN
admet-425	88	41	compartment	compartment	NOUN
admet-425	88	42	.	.	PUNCT
admet-425	89	1	each	each	PRON
admet-425	89	2	of	of	ADP
admet-425	89	3	these	these	DET
admet-425	89	4	two	two	NUM
admet-425	89	5	processes	process	NOUN
admet-425	89	6	can	can	AUX
admet-425	89	7	limit	limit	VERB
admet-425	89	8	the	the	DET
admet-425	89	9	overall	overall	ADJ
admet-425	89	10	drug	drug	NOUN
admet-425	89	11	release	release	NOUN
admet-425	89	12	rate	rate	NOUN
admet-425	89	13	.	.	PUNCT
admet-425	90	1	if	if	SCONJ
admet-425	90	2	diffusion	diffusion	NOUN
admet-425	90	3	through	through	ADP
admet-425	90	4	the	the	DET
admet-425	90	5	dialysis	dialysis	NOUN
admet-425	90	6	membrane	membrane	NOUN
admet-425	90	7	is	be	AUX
admet-425	90	8	the	the	DET
admet-425	90	9	limiting	limit	VERB
admet-425	90	10	factor	factor	NOUN
admet-425	90	11	,	,	PUNCT
admet-425	90	12	then	then	ADV
admet-425	90	13	the	the	DET
admet-425	90	14	results	result	NOUN
admet-425	90	15	obtained	obtain	VERB
admet-425	90	16	do	do	AUX
admet-425	90	17	not	not	PART
admet-425	90	18	say	say	VERB
admet-425	90	19	much	much	ADJ
admet-425	90	20	about	about	ADP
admet-425	90	21	the	the	DET
admet-425	90	22	kinetics	kinetic	NOUN
admet-425	90	23	of	of	ADP
admet-425	90	24	the	the	DET
admet-425	90	25	drug	drug	NOUN
admet-425	90	26	release	release	NOUN
admet-425	90	27	from	from	ADP
admet-425	90	28	the	the	DET
admet-425	90	29	carrier	carrier	NOUN
admet-425	90	30	.	.	PUNCT
admet-425	91	1	therefore	therefore	ADV
admet-425	91	2	,	,	PUNCT
admet-425	91	3	to	to	PART
admet-425	91	4	account	account	VERB
admet-425	91	5	for	for	ADP
admet-425	91	6	the	the	DET
admet-425	91	7	resistance	resistance	NOUN
admet-425	91	8	of	of	ADP
admet-425	91	9	the	the	DET
admet-425	91	10	dialysis	dialysis	NOUN
admet-425	91	11	membrane	membrane	NOUN
admet-425	91	12	to	to	ADP
admet-425	91	13	drug	drug	NOUN
admet-425	91	14	diffusion	diffusion	NOUN
admet-425	91	15	and	and	CCONJ
admet-425	91	16	its	its	PRON
admet-425	91	17	influence	influence	NOUN
admet-425	91	18	on	on	ADP
admet-425	91	19	the	the	DET
admet-425	91	20	overall	overall	ADJ
admet-425	91	21	drug	drug	NOUN
admet-425	91	22	release	release	NOUN
admet-425	91	23	rate	rate	NOUN
admet-425	91	24	,	,	PUNCT
admet-425	91	25	an	an	DET
admet-425	91	26	in	in	ADP
admet-425	91	27	vitro	vitro	X
admet-425	91	28	release	release	NOUN
admet-425	91	29	study	study	NOUN
admet-425	91	30	has	have	VERB
admet-425	91	31	to	to	PART
admet-425	91	32	be	be	AUX
admet-425	91	33	performed	perform	VERB
admet-425	91	34	with	with	ADP
admet-425	91	35	the	the	DET
admet-425	91	36	drug	drug	NOUN
admet-425	91	37	solution	solution	NOUN
admet-425	91	38	too	too	ADV
admet-425	91	39	.	.	PUNCT
admet-425	92	1	furthermore	furthermore	ADV
admet-425	92	2	,	,	PUNCT
admet-425	92	3	the	the	DET
admet-425	92	4	possibility	possibility	NOUN
admet-425	92	5	of	of	ADP
admet-425	92	6	reversible	reversible	ADJ
admet-425	92	7	binding	binding	NOUN
admet-425	92	8	of	of	ADP
admet-425	92	9	the	the	DET
admet-425	92	10	released	release	VERB
admet-425	92	11	drug	drug	NOUN
admet-425	92	12	onto	onto	ADP
admet-425	92	13	a	a	DET
admet-425	92	14	carrier	carrier	NOUN
admet-425	92	15	in	in	ADP
admet-425	92	16	the	the	DET
admet-425	92	17	donor	donor	NOUN
admet-425	92	18	compartment	compartment	NOUN
admet-425	92	19	must	must	AUX
admet-425	92	20	be	be	AUX
admet-425	92	21	considered	consider	VERB
admet-425	92	22	,	,	PUNCT
admet-425	92	23	which	which	PRON
admet-425	92	24	may	may	AUX
admet-425	92	25	reduce	reduce	VERB
admet-425	92	26	the	the	DET
admet-425	92	27	thermodynamic	thermodynamic	ADJ
admet-425	92	28	activity	activity	NOUN
admet-425	92	29	of	of	ADP
admet-425	92	30	the	the	DET
admet-425	92	31	drug	drug	NOUN
admet-425	92	32	in	in	ADP
admet-425	92	33	the	the	DET
admet-425	92	34	donor	donor	NOUN
admet-425	92	35	compartment	compartment	NOUN
admet-425	92	36	and	and	CCONJ
admet-425	92	37	thus	thus	ADV
admet-425	92	38	the	the	DET
admet-425	92	39	diffusion	diffusion	NOUN
admet-425	92	40	rate	rate	NOUN
admet-425	92	41	.	.	PUNCT
admet-425	93	1	this	this	PRON
admet-425	93	2	may	may	AUX
admet-425	93	3	lead	lead	VERB
admet-425	93	4	to	to	ADP
admet-425	93	5	the	the	DET
admet-425	93	6	wrong	wrong	ADJ
admet-425	93	7	conclusions	conclusion	NOUN
admet-425	93	8	about	about	ADP
admet-425	93	9	the	the	DET
admet-425	93	10	extended	extend	VERB
admet-425	93	11	release	release	NOUN
admet-425	93	12	of	of	ADP
admet-425	93	13	the	the	DET
admet-425	93	14	drug	drug	NOUN
admet-425	93	15	.	.	PUNCT
admet-425	94	1	finally	finally	ADV
admet-425	94	2	,	,	PUNCT
admet-425	94	3	it	it	PRON
admet-425	94	4	is	be	AUX
admet-425	94	5	very	very	ADV
admet-425	94	6	important	important	ADJ
admet-425	94	7	to	to	PART
admet-425	94	8	consider	consider	VERB
admet-425	94	9	that	that	PRON
admet-425	94	10	as	as	SCONJ
admet-425	94	11	drug	drug	NOUN
admet-425	94	12	diffuses	diffuse	VERB
admet-425	94	13	through	through	ADP
admet-425	94	14	the	the	DET
admet-425	94	15	diffusion	diffusion	NOUN
admet-425	94	16	membrane	membrane	NOUN
admet-425	94	17	,	,	PUNCT
admet-425	94	18	the	the	DET
admet-425	94	19	ions	ion	NOUN
admet-425	94	20	diffuse	diffuse	VERB
admet-425	94	21	from	from	ADP
admet-425	94	22	one	one	NUM
admet-425	94	23	compartment	compartment	NOUN
admet-425	94	24	to	to	ADP
admet-425	94	25	another	another	PRON
admet-425	94	26	as	as	ADV
admet-425	94	27	well	well	ADV
admet-425	94	28	.	.	PUNCT
admet-425	95	1	this	this	PRON
admet-425	95	2	is	be	AUX
admet-425	95	3	of	of	ADP
admet-425	95	4	the	the	DET
admet-425	95	5	most	most	ADJ
admet-425	95	6	importance	importance	NOUN
admet-425	95	7	for	for	ADP
admet-425	95	8	ion	ion	NOUN
admet-425	95	9	activated	activate	VERB
admet-425	95	10	in	in	ADP
admet-425	95	11	situ	situ	ADJ
admet-425	95	12	gelling	gelling	NOUN
admet-425	95	13	systems	system	NOUN
admet-425	95	14	for	for	ADP
admet-425	95	15	which	which	PRON
admet-425	95	16	the	the	DET
admet-425	95	17	gelation	gelation	NOUN
admet-425	95	18	as	as	ADV
admet-425	95	19	well	well	ADV
admet-425	95	20	as	as	ADP
admet-425	95	21	gel	gel	NOUN
admet-425	95	22	strength	strength	NOUN
admet-425	95	23	is	be	AUX
admet-425	95	24	related	relate	VERB
admet-425	95	25	to	to	ADP
admet-425	95	26	the	the	DET
admet-425	95	27	concentration	concentration	NOUN
admet-425	95	28	of	of	ADP
admet-425	95	29	crosslinking	crosslinke	VERB
admet-425	95	30	ion	ion	NOUN
admet-425	95	31	such	such	ADJ
admet-425	95	32	as	as	ADP
admet-425	95	33	ca2	ca2	PROPN
admet-425	95	34	+	+	PROPN
admet-425	96	1	[	[	X
admet-425	96	2	3	3	NUM
admet-425	96	3	]	]	PUNCT
admet-425	96	4	.	.	PUNCT
admet-425	97	1	dialysis	dialysis	NOUN
admet-425	97	2	bag	bag	NOUN
admet-425	97	3	with	with	ADP
admet-425	97	4	molecular	molecular	ADJ
admet-425	97	5	weight	weight	NOUN
admet-425	97	6	cut	cut	NOUN
admet-425	97	7	-	-	PUNCT
admet-425	97	8	off	off	NOUN
admet-425	97	9	in	in	ADP
admet-425	97	10	range	range	NOUN
admet-425	97	11	from	from	ADP
admet-425	97	12	8	8	NUM
admet-425	97	13	to	to	PART
admet-425	97	14	14	14	NUM
admet-425	97	15	kda	kda	NOUN
admet-425	97	16	is	be	AUX
admet-425	97	17	the	the	DET
admet-425	97	18	most	most	ADV
admet-425	97	19	frequently	frequently	ADV
admet-425	97	20	used	use	VERB
admet-425	97	21	noncompendial	noncompendial	ADJ
admet-425	97	22	setup	setup	NOUN
admet-425	97	23	among	among	ADP
admet-425	97	24	membrane	membrane	NOUN
admet-425	97	25	diffusion	diffusion	NOUN
admet-425	97	26	methods	method	NOUN
admet-425	97	27	.	.	PUNCT
admet-425	98	1	the	the	DET
admet-425	98	2	volume	volume	NOUN
admet-425	98	3	of	of	ADP
admet-425	98	4	receptor	receptor	NOUN
admet-425	98	5	media	medium	NOUN
admet-425	98	6	is	be	AUX
admet-425	98	7	usually	usually	ADV
admet-425	98	8	between	between	ADP
admet-425	98	9	20	20	NUM
admet-425	98	10	and	and	CCONJ
admet-425	98	11	100	100	NUM
admet-425	98	12	ml	ml	ADV
admet-425	98	13	and	and	CCONJ
admet-425	98	14	stirring	stirring	NOUN
admet-425	98	15	conditions	condition	NOUN
admet-425	98	16	are	be	AUX
admet-425	98	17	ranging	range	VERB
admet-425	98	18	from	from	ADP
admet-425	98	19	50	50	NUM
admet-425	98	20	to	to	PART
admet-425	98	21	150	150	NUM
admet-425	98	22	rpm	rpm	NOUN
admet-425	98	23	.	.	PUNCT
admet-425	99	1	using	use	VERB
admet-425	99	2	dialysis	dialysis	NOUN
admet-425	99	3	method	method	NOUN
admet-425	99	4	,	,	PUNCT
admet-425	99	5	a	a	DET
admet-425	99	6	good	good	ADJ
admet-425	99	7	ivivc	ivivc	VERB
admet-425	99	8	mario	mario	PROPN
admet-425	99	9	jug	jug	PROPN
admet-425	99	10	et	et	PROPN
admet-425	99	11	al	al	PROPN
admet-425	99	12	.	.	PROPN
admet-425	99	13	admet	admet	PROPN
admet-425	99	14	&	&	CCONJ
admet-425	99	15	dmpk	dmpk	PROPN
admet-425	99	16	5(3	5(3	NUM
admet-425	99	17	)	)	PUNCT
admet-425	99	18	(	(	PUNCT
admet-425	99	19	2017	2017	NUM
admet-425	99	20	)	)	PUNCT
admet-425	99	21	173	173	NUM
admet-425	99	22	-	-	SYM
admet-425	99	23	182	182	NUM
admet-425	99	24	178	178	NUM
admet-425	99	25	was	be	AUX
admet-425	99	26	found	find	VERB
admet-425	99	27	for	for	ADP
admet-425	99	28	gatifloxacin	gatifloxacin	NOUN
admet-425	99	29	release	release	NOUN
admet-425	99	30	from	from	ADP
admet-425	99	31	ocular	ocular	ADJ
admet-425	99	32	inserts	insert	NOUN
admet-425	99	33	[	[	X
admet-425	99	34	47	47	NUM
admet-425	99	35	]	]	PUNCT
admet-425	99	36	.	.	PUNCT
admet-425	100	1	level	level	NOUN
admet-425	100	2	a	a	DET
admet-425	100	3	ivivc	ivivc	NOUN
admet-425	100	4	was	be	AUX
admet-425	100	5	also	also	ADV
admet-425	100	6	achieved	achieve	VERB
admet-425	100	7	for	for	ADP
admet-425	100	8	paracetamol	paracetamol	NOUN
admet-425	100	9	release	release	NOUN
admet-425	100	10	from	from	ADP
admet-425	100	11	suppository	suppository	ADJ
admet-425	100	12	formulation	formulation	NOUN
admet-425	100	13	using	use	VERB
admet-425	100	14	similar	similar	ADJ
admet-425	100	15	apparatus	apparatus	NOUN
admet-425	100	16	setup	setup	NOUN
admet-425	100	17	[	[	X
admet-425	100	18	48	48	NUM
admet-425	100	19	]	]	PUNCT
admet-425	100	20	.	.	PUNCT
admet-425	101	1	dialysis	dialysis	NOUN
admet-425	101	2	bag	bag	NOUN
admet-425	101	3	is	be	AUX
admet-425	101	4	also	also	ADV
admet-425	101	5	widely	widely	ADV
admet-425	101	6	used	use	VERB
admet-425	101	7	to	to	PART
admet-425	101	8	study	study	VERB
admet-425	101	9	the	the	DET
admet-425	101	10	in	in	ADV
admet-425	101	11	vitro	vitro	X
admet-425	101	12	release	release	NOUN
admet-425	101	13	properties	property	NOUN
admet-425	101	14	of	of	ADP
admet-425	101	15	semisolid	semisolid	NOUN
admet-425	101	16	and	and	CCONJ
admet-425	101	17	nanoparticulate	nanoparticulate	NOUN
admet-425	101	18	formulations	formulation	NOUN
admet-425	101	19	aimed	aim	VERB
admet-425	101	20	for	for	ADP
admet-425	101	21	ocular	ocular	ADJ
admet-425	101	22	,	,	PUNCT
admet-425	101	23	nasal	nasal	NOUN
admet-425	101	24	and	and	CCONJ
admet-425	101	25	vaginal	vaginal	ADJ
admet-425	101	26	drug	drug	NOUN
admet-425	101	27	delivery	delivery	NOUN
admet-425	102	1	[	[	X
admet-425	102	2	3	3	NUM
admet-425	102	3	]	]	PUNCT
admet-425	102	4	.	.	PUNCT
admet-425	103	1	in	in	ADP
admet-425	103	2	some	some	DET
admet-425	103	3	cases	case	NOUN
admet-425	103	4	,	,	PUNCT
admet-425	103	5	the	the	DET
admet-425	103	6	dialysis	dialysis	NOUN
admet-425	103	7	bag	bag	NOUN
admet-425	103	8	is	be	AUX
admet-425	103	9	introduced	introduce	VERB
admet-425	103	10	to	to	ADP
admet-425	103	11	the	the	DET
admet-425	103	12	basket	basket	NOUN
admet-425	103	13	of	of	ADP
admet-425	103	14	apparatus	apparatus	NOUN
admet-425	103	15	1	1	NUM
admet-425	103	16	or	or	CCONJ
admet-425	103	17	attached	attach	VERB
admet-425	103	18	onto	onto	ADP
admet-425	103	19	the	the	DET
admet-425	103	20	paddle	paddle	NOUN
admet-425	103	21	of	of	ADP
admet-425	103	22	the	the	DET
admet-425	103	23	apparatus	apparatus	NOUN
admet-425	103	24	2	2	NUM
admet-425	103	25	.	.	PUNCT
admet-425	104	1	another	another	DET
admet-425	104	2	setup	setup	NOUN
admet-425	104	3	includes	include	VERB
admet-425	104	4	the	the	DET
admet-425	104	5	use	use	NOUN
admet-425	104	6	of	of	ADP
admet-425	104	7	a	a	DET
admet-425	104	8	glass	glass	NOUN
admet-425	104	9	cylinder	cylinder	NOUN
admet-425	104	10	containing	contain	VERB
admet-425	104	11	the	the	DET
admet-425	104	12	formulation	formulation	NOUN
admet-425	104	13	,	,	PUNCT
admet-425	104	14	sealed	seal	VERB
admet-425	104	15	at	at	ADP
admet-425	104	16	the	the	DET
admet-425	104	17	bottom	bottom	NOUN
admet-425	104	18	with	with	ADP
admet-425	104	19	the	the	DET
admet-425	104	20	semipermeable	semipermeable	ADJ
admet-425	104	21	membrane	membrane	NOUN
admet-425	104	22	and	and	CCONJ
admet-425	104	23	vertically	vertically	ADV
admet-425	104	24	immersed	immerse	VERB
admet-425	104	25	into	into	ADP
admet-425	104	26	the	the	DET
admet-425	104	27	dissolution	dissolution	ADJ
admet-425	104	28	medium	medium	NOUN
admet-425	104	29	.	.	PUNCT
admet-425	105	1	such	such	ADJ
admet-425	105	2	apparatus	apparatus	NOUN
admet-425	105	3	is	be	AUX
admet-425	105	4	used	use	VERB
admet-425	105	5	for	for	ADP
admet-425	105	6	in	in	ADP
admet-425	105	7	vitro	vitro	X
admet-425	105	8	release	release	NOUN
admet-425	105	9	testing	testing	NOUN
admet-425	105	10	of	of	ADP
admet-425	105	11	rectal	rectal	ADJ
admet-425	105	12	suppositories	suppository	NOUN
admet-425	105	13	[	[	X
admet-425	105	14	49	49	NUM
admet-425	105	15	]	]	PUNCT
admet-425	105	16	.	.	PUNCT
admet-425	106	1	the	the	DET
admet-425	106	2	compendial	compendial	ADJ
admet-425	106	3	flow	flow	NOUN
admet-425	106	4	through	through	ADP
admet-425	106	5	apparatus	apparatus	NOUN
admet-425	106	6	(	(	PUNCT
admet-425	106	7	apparatus	apparatus	NOUN
admet-425	106	8	4	4	NUM
admet-425	106	9	;	;	PUNCT
admet-425	106	10	figure	figure	NOUN
admet-425	106	11	3	3	NUM
admet-425	106	12	)	)	PUNCT
admet-425	106	13	can	can	AUX
admet-425	106	14	be	be	AUX
admet-425	106	15	used	use	VERB
admet-425	106	16	in	in	ADP
admet-425	106	17	combination	combination	NOUN
admet-425	106	18	with	with	ADP
admet-425	106	19	a	a	DET
admet-425	106	20	membrane	membrane	NOUN
admet-425	106	21	containing	contain	VERB
admet-425	106	22	adapter	adapter	NOUN
admet-425	106	23	.	.	PUNCT
admet-425	107	1	this	this	DET
admet-425	107	2	setup	setup	NOUN
admet-425	107	3	is	be	AUX
admet-425	107	4	widely	widely	ADV
admet-425	107	5	employed	employ	VERB
admet-425	107	6	for	for	ADP
admet-425	107	7	in	in	ADP
admet-425	107	8	vitro	vitro	X
admet-425	107	9	drug	drug	NOUN
admet-425	107	10	release	release	NOUN
admet-425	107	11	testing	testing	NOUN
admet-425	107	12	from	from	ADP
admet-425	107	13	ocular	ocular	ADJ
admet-425	107	14	inserts	insert	NOUN
admet-425	107	15	[	[	PUNCT
admet-425	107	16	50	50	NUM
admet-425	107	17	]	]	PUNCT
admet-425	107	18	and	and	CCONJ
admet-425	107	19	contact	contact	NOUN
admet-425	107	20	lenses	lense	NOUN
admet-425	107	21	[	[	X
admet-425	107	22	51	51	NUM
admet-425	107	23	]	]	PUNCT
admet-425	107	24	.	.	PUNCT
admet-425	108	1	sometimes	sometimes	ADV
admet-425	108	2	is	be	AUX
admet-425	108	3	also	also	ADV
admet-425	108	4	used	use	VERB
admet-425	108	5	in	in	ADP
admet-425	108	6	case	case	NOUN
admet-425	108	7	of	of	ADP
admet-425	108	8	semisolid	semisolid	NOUN
admet-425	108	9	dosage	dosage	NOUN
admet-425	108	10	forms	form	NOUN
admet-425	108	11	[	[	X
admet-425	108	12	6	6	NUM
admet-425	108	13	]	]	PUNCT
admet-425	108	14	,	,	PUNCT
admet-425	108	15	microparticles	microparticle	NOUN
admet-425	108	16	for	for	ADP
admet-425	108	17	nasal	nasal	ADJ
admet-425	108	18	application	application	NOUN
admet-425	108	19	[	[	X
admet-425	108	20	52	52	NUM
admet-425	108	21	]	]	PUNCT
admet-425	108	22	and	and	CCONJ
admet-425	108	23	thermosensitive	thermosensitive	ADJ
admet-425	108	24	gels	gel	NOUN
admet-425	108	25	for	for	ADP
admet-425	108	26	buccal	buccal	ADJ
admet-425	108	27	application	application	NOUN
admet-425	109	1	[	[	X
admet-425	109	2	53	53	NUM
admet-425	109	3	]	]	PUNCT
admet-425	109	4	.	.	PUNCT
admet-425	110	1	this	this	DET
admet-425	110	2	apparatus	apparatus	NOUN
admet-425	110	3	allows	allow	VERB
admet-425	110	4	the	the	DET
admet-425	110	5	drug	drug	NOUN
admet-425	110	6	release	release	NOUN
admet-425	110	7	testing	testing	NOUN
admet-425	110	8	under	under	ADP
admet-425	110	9	physiological	physiological	ADJ
admet-425	110	10	flow	flow	NOUN
admet-425	110	11	rate	rate	NOUN
admet-425	110	12	of	of	ADP
admet-425	110	13	the	the	DET
admet-425	110	14	dissolution	dissolution	NOUN
admet-425	110	15	medium	medium	NOUN
admet-425	110	16	and	and	CCONJ
admet-425	110	17	offers	offer	VERB
admet-425	110	18	ability	ability	NOUN
admet-425	110	19	to	to	PART
admet-425	110	20	maintain	maintain	VERB
admet-425	110	21	the	the	DET
admet-425	110	22	sink	sink	NOUN
admet-425	110	23	conditions	condition	NOUN
admet-425	110	24	while	while	SCONJ
admet-425	110	25	operating	operate	VERB
admet-425	110	26	in	in	ADP
admet-425	110	27	an	an	DET
admet-425	110	28	open	open	ADJ
admet-425	110	29	system	system	NOUN
admet-425	110	30	setup	setup	NOUN
admet-425	110	31	.	.	PUNCT
admet-425	111	1	besides	besides	SCONJ
admet-425	111	2	compendial	compendial	ADJ
admet-425	111	3	,	,	PUNCT
admet-425	111	4	some	some	DET
admet-425	111	5	self	self	NOUN
admet-425	111	6	-	-	PUNCT
admet-425	111	7	made	make	VERB
admet-425	111	8	flow	flow	NOUN
admet-425	111	9	through	through	ADP
admet-425	111	10	apparatuses	apparatus	NOUN
admet-425	111	11	were	be	AUX
admet-425	111	12	also	also	ADV
admet-425	111	13	used	use	VERB
admet-425	111	14	[	[	PUNCT
admet-425	111	15	54	54	NUM
admet-425	111	16	]	]	PUNCT
admet-425	111	17	.	.	PUNCT
admet-425	112	1	however	however	ADV
admet-425	112	2	,	,	PUNCT
admet-425	112	3	the	the	DET
admet-425	112	4	flow	flow	NOUN
admet-425	112	5	through	through	ADP
admet-425	112	6	method	method	NOUN
admet-425	112	7	shows	show	VERB
admet-425	112	8	some	some	DET
admet-425	112	9	disadvantages	disadvantage	NOUN
admet-425	112	10	,	,	PUNCT
admet-425	112	11	including	include	VERB
admet-425	112	12	instrument	instrument	NOUN
admet-425	112	13	cost	cost	NOUN
admet-425	112	14	and	and	CCONJ
admet-425	112	15	set	set	NOUN
admet-425	112	16	-	-	PUNCT
admet-425	112	17	up	up	NOUN
admet-425	112	18	,	,	PUNCT
admet-425	112	19	filter	filter	NOUN
admet-425	112	20	clogging	clogging	NOUN
admet-425	112	21	,	,	PUNCT
admet-425	112	22	drug	drug	NOUN
admet-425	112	23	adsorption	adsorption	NOUN
admet-425	112	24	to	to	ADP
admet-425	112	25	the	the	DET
admet-425	112	26	apparatus	apparatus	NOUN
admet-425	112	27	,	,	PUNCT
admet-425	112	28	problems	problem	NOUN
admet-425	112	29	to	to	PART
admet-425	112	30	maintain	maintain	VERB
admet-425	112	31	a	a	DET
admet-425	112	32	constant	constant	ADJ
admet-425	112	33	flow	flow	NOUN
admet-425	112	34	rate	rate	NOUN
admet-425	112	35	and	and	CCONJ
admet-425	112	36	consequent	consequent	ADJ
admet-425	112	37	high	high	ADJ
admet-425	112	38	variability	variability	NOUN
admet-425	112	39	in	in	ADP
admet-425	112	40	the	the	DET
admet-425	112	41	results	result	NOUN
admet-425	112	42	[	[	X
admet-425	112	43	39	39	NUM
admet-425	112	44	]	]	PUNCT
admet-425	112	45	.	.	PUNCT
admet-425	113	1	figure	figure	NOUN
admet-425	113	2	3	3	NUM
admet-425	113	3	.	.	PUNCT
admet-425	113	4	schematic	schematic	ADJ
admet-425	113	5	representation	representation	NOUN
admet-425	113	6	of	of	ADP
admet-425	113	7	the	the	DET
admet-425	113	8	flow	flow	NOUN
admet-425	113	9	through	through	ADP
admet-425	113	10	cell	cell	NOUN
admet-425	113	11	.	.	PUNCT
admet-425	114	1	reprinted	reprint	VERB
admet-425	114	2	from	from	ADP
admet-425	114	3	ref	ref	NOUN
admet-425	114	4	.	.	PUNCT
admet-425	115	1	[	[	X
admet-425	115	2	3	3	X
admet-425	115	3	]	]	PUNCT
admet-425	115	4	with	with	ADP
admet-425	115	5	permission	permission	NOUN
admet-425	115	6	of	of	ADP
admet-425	115	7	elsevier	elsevier	PROPN
admet-425	115	8	.	.	PUNCT
admet-425	116	1	franz	franz	PROPN
admet-425	116	2	-	-	PUNCT
admet-425	116	3	diffusion	diffusion	NOUN
admet-425	116	4	cell	cell	NOUN
admet-425	116	5	(	(	PUNCT
admet-425	116	6	i.e.	i.e.	X
admet-425	116	7	vertical	vertical	ADJ
admet-425	116	8	diffusion	diffusion	NOUN
admet-425	116	9	cell	cell	NOUN
admet-425	116	10	,	,	PUNCT
admet-425	116	11	figure	figure	NOUN
admet-425	116	12	4	4	NUM
admet-425	116	13	)	)	PUNCT
admet-425	116	14	was	be	AUX
admet-425	116	15	originally	originally	ADV
admet-425	116	16	developed	develop	VERB
admet-425	116	17	for	for	ADP
admet-425	116	18	in	in	ADP
admet-425	116	19	vitro	vitro	X
admet-425	116	20	drug	drug	NOUN
admet-425	116	21	release	release	NOUN
admet-425	116	22	testing	testing	NOUN
admet-425	116	23	from	from	ADP
admet-425	116	24	dermal	dermal	ADJ
admet-425	116	25	creams	cream	NOUN
admet-425	116	26	,	,	PUNCT
admet-425	116	27	ointments	ointment	NOUN
admet-425	116	28	and	and	CCONJ
admet-425	116	29	gels	gel	NOUN
admet-425	116	30	,	,	PUNCT
admet-425	116	31	but	but	CCONJ
admet-425	116	32	nowadays	nowadays	ADV
admet-425	116	33	is	be	AUX
admet-425	116	34	widely	widely	ADV
admet-425	116	35	used	use	VERB
admet-425	116	36	to	to	PART
admet-425	116	37	test	test	VERB
admet-425	116	38	in	in	ADP
admet-425	116	39	vitro	vitro	X
admet-425	116	40	drug	drug	NOUN
admet-425	116	41	release	release	NOUN
admet-425	116	42	from	from	ADP
admet-425	116	43	various	various	ADJ
admet-425	116	44	mucosal	mucosal	NOUN
admet-425	116	45	delivery	delivery	NOUN
admet-425	116	46	systems	system	NOUN
admet-425	116	47	.	.	PUNCT
admet-425	117	1	the	the	DET
admet-425	117	2	formulation	formulation	NOUN
admet-425	117	3	loaded	load	VERB
admet-425	117	4	into	into	ADP
admet-425	117	5	upper	upper	ADJ
admet-425	117	6	donor	donor	NOUN
admet-425	117	7	compartment	compartment	NOUN
admet-425	117	8	is	be	AUX
admet-425	117	9	separated	separate	VERB
admet-425	117	10	from	from	ADP
admet-425	117	11	the	the	DET
admet-425	117	12	receptor	receptor	NOUN
admet-425	117	13	medium	medium	NOUN
admet-425	117	14	present	present	NOUN
admet-425	117	15	in	in	ADP
admet-425	117	16	the	the	DET
admet-425	117	17	lower	low	ADJ
admet-425	117	18	compartment	compartment	NOUN
admet-425	117	19	by	by	ADP
admet-425	117	20	a	a	DET
admet-425	117	21	semipermeable	semipermeable	ADJ
admet-425	117	22	membrane	membrane	NOUN
admet-425	117	23	.	.	PUNCT
admet-425	118	1	franz	franz	NOUN
admet-425	118	2	-	-	PUNCT
admet-425	118	3	diffusion	diffusion	NOUN
admet-425	118	4	cell	cell	NOUN
admet-425	118	5	was	be	AUX
admet-425	118	6	used	use	VERB
admet-425	118	7	to	to	PART
admet-425	118	8	assess	assess	VERB
admet-425	118	9	the	the	DET
admet-425	118	10	drug	drug	NOUN
admet-425	118	11	release	release	NOUN
admet-425	118	12	properties	property	NOUN
admet-425	118	13	from	from	ADP
admet-425	118	14	numerous	numerous	ADJ
admet-425	118	15	formulations	formulation	NOUN
admet-425	118	16	aimed	aim	VERB
admet-425	118	17	for	for	ADP
admet-425	118	18	nasal	nasal	ADJ
admet-425	118	19	application	application	NOUN
admet-425	118	20	,	,	PUNCT
admet-425	118	21	such	such	ADJ
admet-425	118	22	as	as	ADP
admet-425	118	23	thermoresponsive	thermoresponsive	ADJ
admet-425	118	24	soluble	soluble	ADJ
admet-425	118	25	gels	gel	NOUN
admet-425	118	26	[	[	X
admet-425	118	27	55	55	NUM
admet-425	118	28	]	]	PUNCT
admet-425	118	29	,	,	PUNCT
admet-425	118	30	ion	ion	NOUN
admet-425	118	31	activated	activate	VERB
admet-425	118	32	in	in	ADP
admet-425	118	33	situ	situ	ADJ
admet-425	118	34	gels	gel	NOUN
admet-425	118	35	[	[	X
admet-425	118	36	56	56	NUM
admet-425	118	37	]	]	PUNCT
admet-425	118	38	,	,	PUNCT
admet-425	118	39	microparticles	microparticle	NOUN
admet-425	118	40	[	[	X
admet-425	118	41	57	57	NUM
admet-425	118	42	]	]	PUNCT
admet-425	118	43	,	,	PUNCT
admet-425	118	44	nanostructured	nanostructure	VERB
admet-425	118	45	lipid	lipid	NOUN
admet-425	118	46	carriers	carrier	NOUN
admet-425	118	47	[	[	X
admet-425	118	48	58	58	NUM
admet-425	118	49	]	]	PUNCT
admet-425	118	50	,	,	PUNCT
admet-425	118	51	gel	gel	NOUN
admet-425	118	52	containing	contain	VERB
admet-425	118	53	microspheres	microsphere	NOUN
admet-425	118	54	[	[	X
admet-425	118	55	59	59	NUM
admet-425	118	56	]	]	PUNCT
admet-425	118	57	,	,	PUNCT
admet-425	118	58	lipidic	lipidic	ADJ
admet-425	118	59	emulsomes	emulsome	NOUN
admet-425	119	1	[	[	X
admet-425	119	2	60	60	NUM
admet-425	119	3	]	]	PUNCT
admet-425	119	4	,	,	PUNCT
admet-425	119	5	in	in	ADP
admet-425	119	6	situ	situ	ADJ
admet-425	119	7	gelling	gelling	NOUN
admet-425	119	8	microemulsions	microemulsion	NOUN
admet-425	119	9	[	[	X
admet-425	119	10	61	61	NUM
admet-425	119	11	]	]	PUNCT
admet-425	119	12	and	and	CCONJ
admet-425	119	13	solid	solid	ADJ
admet-425	119	14	lipid	lipid	NOUN
admet-425	119	15	nanoparticles	nanoparticle	NOUN
admet-425	119	16	[	[	X
admet-425	119	17	62	62	NUM
admet-425	119	18	]	]	PUNCT
admet-425	119	19	.	.	PUNCT
admet-425	120	1	this	this	DET
admet-425	120	2	method	method	NOUN
admet-425	120	3	is	be	AUX
admet-425	120	4	advantageous	advantageous	ADJ
admet-425	120	5	over	over	ADP
admet-425	120	6	other	other	ADJ
admet-425	120	7	compendial	compendial	ADJ
admet-425	120	8	and	and	CCONJ
admet-425	120	9	non	non	ADJ
admet-425	120	10	-	-	ADJ
admet-425	120	11	compendial	compendial	ADJ
admet-425	120	12	membrane	membrane	NOUN
admet-425	120	13	diffusion	diffusion	NOUN
admet-425	120	14	methods	method	NOUN
admet-425	120	15	particularly	particularly	ADV
admet-425	120	16	in	in	ADP
admet-425	120	17	case	case	NOUN
admet-425	120	18	of	of	ADP
admet-425	120	19	dry	dry	ADJ
admet-425	120	20	powders	powder	NOUN
admet-425	120	21	as	as	SCONJ
admet-425	120	22	it	it	PRON
admet-425	120	23	allows	allow	VERB
admet-425	120	24	them	they	PRON
admet-425	120	25	to	to	PART
admet-425	120	26	hydrate	hydrate	VERB
admet-425	120	27	slowly	slowly	ADV
admet-425	120	28	,	,	PUNCT
admet-425	120	29	and	and	CCONJ
admet-425	120	30	gel	gel	NOUN
admet-425	120	31	eventually	eventually	ADV
admet-425	120	32	,	,	PUNCT
admet-425	120	33	in	in	ADP
admet-425	120	34	humid	humid	ADJ
admet-425	120	35	environment	environment	NOUN
admet-425	120	36	conditions	condition	NOUN
admet-425	120	37	designed	design	VERB
admet-425	120	38	to	to	PART
admet-425	120	39	be	be	AUX
admet-425	120	40	similar	similar	ADJ
admet-425	120	41	to	to	ADP
admet-425	120	42	those	those	PRON
admet-425	120	43	encountered	encounter	VERB
admet-425	120	44	in	in	ADP
admet-425	120	45	the	the	DET
admet-425	120	46	nasal	nasal	ADJ
admet-425	120	47	cavity	cavity	NOUN
admet-425	120	48	[	[	X
admet-425	120	49	63	63	NUM
admet-425	120	50	]	]	PUNCT
admet-425	120	51	.	.	PUNCT
admet-425	121	1	it	it	PRON
admet-425	121	2	has	have	AUX
admet-425	121	3	been	be	AUX
admet-425	121	4	also	also	ADV
admet-425	121	5	used	use	VERB
admet-425	121	6	in	in	ADP
admet-425	121	7	case	case	NOUN
admet-425	121	8	of	of	ADP
admet-425	121	9	nano	nano	NOUN
admet-425	121	10	sized	size	VERB
admet-425	121	11	and	and	CCONJ
admet-425	121	12	gelling	gel	VERB
admet-425	121	13	ophthalmic	ophthalmic	ADJ
admet-425	121	14	formulations	formulation	NOUN
admet-425	121	15	[	[	X
admet-425	121	16	64,65	64,65	NOUN
admet-425	121	17	]	]	PUNCT
admet-425	121	18	as	as	ADV
admet-425	121	19	well	well	ADV
admet-425	121	20	as	as	ADP
admet-425	121	21	for	for	ADP
admet-425	121	22	films	film	NOUN
admet-425	121	23	[	[	X
admet-425	121	24	66	66	NUM
admet-425	121	25	]	]	PUNCT
admet-425	121	26	,	,	PUNCT
admet-425	121	27	wafers	wafer	NOUN
admet-425	121	28	[	[	PUNCT
admet-425	121	29	67	67	NUM
admet-425	121	30	]	]	PUNCT
admet-425	121	31	and	and	CCONJ
admet-425	121	32	tablets	tablet	NOUN
admet-425	122	1	[	[	PUNCT
admet-425	122	2	68	68	NUM
admet-425	122	3	]	]	PUNCT
admet-425	122	4	aimed	aim	VERB
admet-425	122	5	for	for	ADP
admet-425	122	6	oromucosal	oromucosal	NOUN
admet-425	122	7	administration	administration	NOUN
admet-425	122	8	.	.	PUNCT
admet-425	123	1	also	also	ADV
admet-425	123	2	,	,	PUNCT
admet-425	123	3	in	in	ADP
admet-425	123	4	majority	majority	NOUN
admet-425	123	5	of	of	ADP
admet-425	123	6	the	the	DET
admet-425	123	7	in	in	X
admet-425	123	8	vitro	vitro	X
admet-425	123	9	drug	drug	NOUN
admet-425	123	10	release	release	NOUN
admet-425	123	11	studies	study	NOUN
admet-425	123	12	from	from	ADP
admet-425	123	13	nanosystem	nanosystem	NOUN
admet-425	123	14	-	-	PUNCT
admet-425	123	15	in	in	ADP
admet-425	123	16	-	-	PUNCT
admet-425	123	17	hydrogel	hydrogel	NOUN
admet-425	123	18	type	type	NOUN
admet-425	123	19	vaginal	vaginal	ADJ
admet-425	123	20	formulations	formulation	NOUN
admet-425	123	21	franz	franz	VERB
admet-425	123	22	diffusion	diffusion	NOUN
admet-425	123	23	-	-	PUNCT
admet-425	123	24	cell	cell	NOUN
admet-425	123	25	method	method	NOUN
admet-425	123	26	was	be	AUX
admet-425	123	27	applied	apply	VERB
admet-425	123	28	[	[	PUNCT
admet-425	123	29	69	69	NUM
admet-425	123	30	]	]	PUNCT
admet-425	123	31	.	.	PUNCT
admet-425	124	1	the	the	DET
admet-425	124	2	restricted	restricted	ADJ
admet-425	124	3	volume	volume	NOUN
admet-425	124	4	of	of	ADP
admet-425	124	5	acceptor	acceptor	NOUN
admet-425	124	6	compartment	compartment	NOUN
admet-425	124	7	is	be	AUX
admet-425	124	8	a	a	DET
admet-425	124	9	drawback	drawback	NOUN
admet-425	124	10	of	of	ADP
admet-425	124	11	the	the	DET
admet-425	124	12	franz	franz	NOUN
admet-425	124	13	diffusion	diffusion	NOUN
admet-425	124	14	apparatus	apparatus	NOUN
admet-425	124	15	,	,	PUNCT
admet-425	124	16	which	which	PRON
admet-425	124	17	might	might	AUX
admet-425	124	18	impair	impair	VERB
admet-425	124	19	significantly	significantly	ADV
admet-425	124	20	the	the	DET
admet-425	124	21	observed	observed	ADJ
admet-425	124	22	drug	drug	NOUN
admet-425	124	23	release	release	NOUN
admet-425	124	24	profile	profile	NOUN
admet-425	124	25	,	,	PUNCT
admet-425	124	26	especially	especially	ADV
admet-425	124	27	in	in	ADP
admet-425	124	28	the	the	DET
admet-425	124	29	case	case	NOUN
admet-425	124	30	of	of	ADP
admet-425	124	31	poorly	poorly	ADV
admet-425	124	32	soluble	soluble	ADJ
admet-425	124	33	drugs	drug	NOUN
admet-425	124	34	.	.	PUNCT
admet-425	125	1	admet	admet	PROPN
admet-425	125	2	&	&	CCONJ
admet-425	125	3	dmpk	dmpk	PROPN
admet-425	125	4	5(3	5(3	NUM
admet-425	125	5	)	)	PUNCT
admet-425	125	6	(	(	PUNCT
admet-425	125	7	2017	2017	NUM
admet-425	125	8	)	)	PUNCT
admet-425	125	9	173	173	NUM
admet-425	125	10	-	-	SYM
admet-425	125	11	182	182	NUM
admet-425	125	12	in	in	ADP
admet-425	125	13	vitro	vitro	X
admet-425	125	14	release	release	NOUN
admet-425	125	15	testing	testing	NOUN
admet-425	125	16	of	of	ADP
admet-425	125	17	mucosal	mucosal	ADJ
admet-425	125	18	drug	drug	NOUN
admet-425	125	19	delivery	delivery	NOUN
admet-425	125	20	systems	system	NOUN
admet-425	125	21	doi	doi	NOUN
admet-425	125	22	:	:	PUNCT
admet-425	125	23	10.5599	10.5599	NUM
admet-425	125	24	/	/	SYM
admet-425	125	25	admet.5.3.425	admet.5.3.425	NUM
admet-425	125	26	179	179	NUM
admet-425	125	27	figure	figure	NOUN
admet-425	125	28	4	4	NUM
admet-425	125	29	.	.	PUNCT
admet-425	125	30	schematic	schematic	ADJ
admet-425	125	31	representation	representation	NOUN
admet-425	125	32	of	of	ADP
admet-425	125	33	the	the	DET
admet-425	125	34	franz	franz	NOUN
admet-425	125	35	-	-	PUNCT
admet-425	125	36	diffusion	diffusion	NOUN
admet-425	125	37	cell	cell	NOUN
admet-425	125	38	.	.	PUNCT
admet-425	126	1	reprinted	reprint	VERB
admet-425	126	2	from	from	ADP
admet-425	126	3	ref	ref	NOUN
admet-425	126	4	.	.	PUNCT
admet-425	127	1	[	[	X
admet-425	127	2	3	3	X
admet-425	127	3	]	]	PUNCT
admet-425	127	4	with	with	ADP
admet-425	127	5	permission	permission	NOUN
admet-425	127	6	of	of	ADP
admet-425	127	7	elsevier	elsevier	NOUN
admet-425	127	8	.	.	PUNCT
admet-425	128	1	the	the	DET
admet-425	128	2	immersion	immersion	NOUN
admet-425	128	3	cell	cell	NOUN
admet-425	128	4	(	(	PUNCT
admet-425	128	5	figure	figure	NOUN
admet-425	128	6	2c	2c	NUM
admet-425	128	7	)	)	PUNCT
admet-425	128	8	,	,	PUNCT
admet-425	128	9	another	another	DET
admet-425	128	10	compendial	compendial	ADJ
admet-425	128	11	membrane	membrane	NOUN
admet-425	128	12	diffusion	diffusion	NOUN
admet-425	128	13	method	method	NOUN
admet-425	128	14	mostly	mostly	ADV
admet-425	128	15	used	use	VERB
admet-425	128	16	for	for	ADP
admet-425	128	17	semisolid	semisolid	ADJ
admet-425	128	18	preparations	preparation	NOUN
admet-425	128	19	,	,	PUNCT
admet-425	128	20	was	be	AUX
admet-425	128	21	successfully	successfully	ADV
admet-425	128	22	applied	apply	VERB
admet-425	128	23	to	to	PART
admet-425	128	24	study	study	VERB
admet-425	128	25	the	the	DET
admet-425	128	26	drug	drug	NOUN
admet-425	128	27	release	release	NOUN
admet-425	128	28	kinetic	kinetic	NOUN
admet-425	128	29	from	from	ADP
admet-425	128	30	microparticles	microparticle	NOUN
admet-425	128	31	aimed	aim	VERB
admet-425	128	32	both	both	CCONJ
admet-425	128	33	for	for	ADP
admet-425	128	34	nasal	nasal	NOUN
admet-425	128	35	and	and	CCONJ
admet-425	128	36	dermal	dermal	ADJ
admet-425	128	37	application	application	NOUN
admet-425	128	38	[	[	X
admet-425	128	39	70	70	NUM
admet-425	128	40	]	]	PUNCT
admet-425	128	41	.	.	PUNCT
admet-425	129	1	recently	recently	ADV
admet-425	129	2	,	,	PUNCT
admet-425	129	3	some	some	DET
admet-425	129	4	membrane	membrane	NOUN
admet-425	129	5	-	-	PUNCT
admet-425	129	6	less	less	ADJ
admet-425	129	7	diffusion	diffusion	NOUN
admet-425	129	8	methods	method	NOUN
admet-425	129	9	have	have	AUX
admet-425	129	10	been	be	AUX
admet-425	129	11	reported	report	VERB
admet-425	129	12	to	to	PART
admet-425	129	13	study	study	VERB
admet-425	129	14	the	the	DET
admet-425	129	15	drug	drug	NOUN
admet-425	129	16	release	release	NOUN
admet-425	129	17	from	from	ADP
admet-425	129	18	ocular	ocular	ADJ
admet-425	129	19	inserts	insert	NOUN
admet-425	129	20	[	[	PUNCT
admet-425	129	21	64	64	NUM
admet-425	129	22	]	]	PUNCT
admet-425	129	23	and	and	CCONJ
admet-425	129	24	nasal	nasal	NOUN
admet-425	129	25	in	in	ADP
admet-425	129	26	situ	situ	ADJ
admet-425	129	27	forming	form	VERB
admet-425	129	28	gels	gel	NOUN
admet-425	129	29	[	[	X
admet-425	129	30	20	20	NUM
admet-425	129	31	]	]	PUNCT
admet-425	129	32	,	,	PUNCT
admet-425	129	33	providing	provide	VERB
admet-425	129	34	the	the	DET
admet-425	129	35	direct	direct	ADJ
admet-425	129	36	contact	contact	NOUN
admet-425	129	37	of	of	ADP
admet-425	129	38	the	the	DET
admet-425	129	39	formulation	formulation	NOUN
admet-425	129	40	with	with	ADP
admet-425	129	41	the	the	DET
admet-425	129	42	dissolution	dissolution	PROPN
admet-425	129	43	medium	medium	NOUN
admet-425	129	44	.	.	PUNCT
admet-425	130	1	agarose	agarose	NOUN
admet-425	130	2	method	method	NOUN
admet-425	130	3	is	be	AUX
admet-425	130	4	another	another	DET
admet-425	130	5	membrane	membrane	NOUN
admet-425	130	6	-	-	PUNCT
admet-425	130	7	less	less	ADJ
admet-425	130	8	diffusion	diffusion	NOUN
admet-425	130	9	model	model	NOUN
admet-425	130	10	which	which	PRON
admet-425	130	11	allows	allow	VERB
admet-425	130	12	to	to	PART
admet-425	130	13	monitor	monitor	VERB
admet-425	130	14	the	the	DET
admet-425	130	15	release	release	NOUN
admet-425	130	16	of	of	ADP
admet-425	130	17	both	both	CCONJ
admet-425	130	18	the	the	DET
admet-425	130	19	released	release	VERB
admet-425	130	20	drug	drug	NOUN
admet-425	130	21	and	and	CCONJ
admet-425	130	22	liposomally	liposomally	ADV
admet-425	130	23	associated	associate	VERB
admet-425	130	24	drug	drug	NOUN
admet-425	130	25	in	in	ADP
admet-425	130	26	environment	environment	NOUN
admet-425	130	27	simulating	simulate	VERB
admet-425	130	28	the	the	DET
admet-425	130	29	conditions	condition	NOUN
admet-425	130	30	presented	present	VERB
admet-425	130	31	at	at	ADP
admet-425	130	32	the	the	DET
admet-425	130	33	vaginal	vaginal	ADJ
admet-425	130	34	site	site	NOUN
admet-425	130	35	[	[	X
admet-425	130	36	71	71	NUM
admet-425	130	37	]	]	PUNCT
admet-425	130	38	.	.	PUNCT
admet-425	131	1	sample	sample	NOUN
admet-425	131	2	and	and	CCONJ
admet-425	131	3	separate	separate	ADJ
admet-425	131	4	method	method	NOUN
admet-425	131	5	sample	sample	NOUN
admet-425	131	6	and	and	CCONJ
admet-425	131	7	separate	separate	ADJ
admet-425	131	8	method	method	NOUN
admet-425	131	9	is	be	AUX
admet-425	131	10	simple	simple	ADJ
admet-425	131	11	and	and	CCONJ
admet-425	131	12	provides	provide	VERB
admet-425	131	13	a	a	DET
admet-425	131	14	direct	direct	ADJ
admet-425	131	15	approach	approach	NOUN
admet-425	131	16	to	to	PART
admet-425	131	17	determine	determine	VERB
admet-425	131	18	the	the	DET
admet-425	131	19	drug	drug	NOUN
admet-425	131	20	release	release	NOUN
admet-425	131	21	.	.	PUNCT
admet-425	132	1	dosage	dosage	NOUN
admet-425	132	2	form	form	NOUN
admet-425	132	3	is	be	AUX
admet-425	132	4	introduced	introduce	VERB
admet-425	132	5	into	into	ADP
admet-425	132	6	the	the	DET
admet-425	132	7	release	release	NOUN
admet-425	132	8	medium	medium	NOUN
admet-425	132	9	maintained	maintain	VERB
admet-425	132	10	at	at	ADP
admet-425	132	11	a	a	DET
admet-425	132	12	constant	constant	ADJ
admet-425	132	13	temperature	temperature	NOUN
admet-425	132	14	and	and	CCONJ
admet-425	132	15	the	the	DET
admet-425	132	16	drug	drug	NOUN
admet-425	132	17	release	release	NOUN
admet-425	132	18	is	be	AUX
admet-425	132	19	assessed	assess	VERB
admet-425	132	20	by	by	ADP
admet-425	132	21	sampling	sample	VERB
admet-425	132	22	of	of	ADP
admet-425	132	23	the	the	DET
admet-425	132	24	release	release	NOUN
admet-425	132	25	medium	medium	NOUN
admet-425	132	26	at	at	ADP
admet-425	132	27	defined	define	VERB
admet-425	132	28	time	time	NOUN
admet-425	132	29	,	,	PUNCT
admet-425	132	30	separated	separate	VERB
admet-425	132	31	by	by	ADP
admet-425	132	32	filtration	filtration	NOUN
admet-425	132	33	[	[	X
admet-425	132	34	72	72	NUM
admet-425	132	35	]	]	PUNCT
admet-425	132	36	or	or	CCONJ
admet-425	132	37	centrifugation	centrifugation	NOUN
admet-425	133	1	[	[	X
admet-425	133	2	73	73	NUM
admet-425	133	3	]	]	PUNCT
admet-425	133	4	and	and	CCONJ
admet-425	133	5	quantified	quantify	VERB
admet-425	133	6	by	by	ADP
admet-425	133	7	a	a	DET
admet-425	133	8	suitable	suitable	ADJ
admet-425	133	9	analytical	analytical	ADJ
admet-425	133	10	technique	technique	NOUN
admet-425	133	11	[	[	X
admet-425	133	12	3	3	NUM
admet-425	133	13	]	]	PUNCT
admet-425	133	14	.	.	PUNCT
admet-425	134	1	the	the	DET
admet-425	134	2	volume	volume	NOUN
admet-425	134	3	of	of	ADP
admet-425	134	4	the	the	DET
admet-425	134	5	receptor	receptor	NOUN
admet-425	134	6	medium	medium	NOUN
admet-425	134	7	should	should	AUX
admet-425	134	8	be	be	AUX
admet-425	134	9	adjusted	adjust	VERB
admet-425	134	10	to	to	PART
admet-425	134	11	maintain	maintain	VERB
admet-425	134	12	sink	sink	NOUN
admet-425	134	13	conditions	condition	NOUN
admet-425	134	14	.	.	PUNCT
admet-425	135	1	this	this	DET
admet-425	135	2	approach	approach	NOUN
admet-425	135	3	is	be	AUX
admet-425	135	4	applicable	applicable	ADJ
admet-425	135	5	if	if	SCONJ
admet-425	135	6	the	the	DET
admet-425	135	7	drug	drug	NOUN
admet-425	135	8	release	release	NOUN
admet-425	135	9	lasts	last	VERB
admet-425	135	10	much	much	ADV
admet-425	135	11	longer	long	ADV
admet-425	135	12	(	(	PUNCT
admet-425	135	13	in	in	ADP
admet-425	135	14	hours	hour	NOUN
admet-425	135	15	)	)	PUNCT
admet-425	135	16	than	than	ADP
admet-425	135	17	the	the	DET
admet-425	135	18	particle	particle	NOUN
admet-425	135	19	separation	separation	NOUN
admet-425	135	20	(	(	PUNCT
admet-425	135	21	in	in	ADP
admet-425	135	22	minutes	minute	NOUN
admet-425	135	23	)	)	PUNCT
admet-425	135	24	process	process	NOUN
admet-425	135	25	and	and	CCONJ
admet-425	135	26	is	be	AUX
admet-425	135	27	often	often	ADV
admet-425	135	28	used	use	VERB
admet-425	135	29	to	to	PART
admet-425	135	30	test	test	VERB
admet-425	135	31	in	in	ADP
admet-425	135	32	vitro	vitro	X
admet-425	135	33	drug	drug	NOUN
admet-425	135	34	release	release	NOUN
admet-425	135	35	from	from	ADP
admet-425	135	36	nasal	nasal	PROPN
admet-425	135	37	microand	microand	PROPN
admet-425	135	38	nano	nano	NOUN
admet-425	135	39	-	-	PUNCT
admet-425	135	40	sized	sized	ADJ
admet-425	135	41	delivery	delivery	NOUN
admet-425	135	42	systems	system	NOUN
admet-425	136	1	[	[	X
admet-425	136	2	72,74	72,74	X
admet-425	136	3	]	]	X
admet-425	136	4	.	.	PUNCT
admet-425	137	1	as	as	SCONJ
admet-425	137	2	the	the	DET
admet-425	137	3	particle	particle	NOUN
admet-425	137	4	size	size	NOUN
admet-425	137	5	decreases	decrease	VERB
admet-425	137	6	,	,	PUNCT
admet-425	137	7	the	the	DET
admet-425	137	8	difficulties	difficulty	NOUN
admet-425	137	9	of	of	ADP
admet-425	137	10	separation	separation	NOUN
admet-425	137	11	increase	increase	NOUN
admet-425	137	12	.	.	PUNCT
admet-425	138	1	complete	complete	ADJ
admet-425	138	2	separation	separation	NOUN
admet-425	138	3	of	of	ADP
admet-425	138	4	nanoparticles	nanoparticle	NOUN
admet-425	138	5	requires	require	VERB
admet-425	138	6	ultracentrifugation	ultracentrifugation	NOUN
admet-425	138	7	or	or	CCONJ
admet-425	138	8	ultrafiltration	ultrafiltration	NOUN
admet-425	138	9	.	.	PUNCT
admet-425	139	1	the	the	DET
admet-425	139	2	application	application	NOUN
admet-425	139	3	of	of	ADP
admet-425	139	4	such	such	DET
admet-425	139	5	a	a	DET
admet-425	139	6	strong	strong	ADJ
admet-425	139	7	force	force	NOUN
admet-425	139	8	for	for	ADP
admet-425	139	9	particle	particle	NOUN
admet-425	139	10	separation	separation	NOUN
admet-425	139	11	may	may	AUX
admet-425	139	12	impair	impair	VERB
admet-425	139	13	their	their	PRON
admet-425	139	14	integrity	integrity	NOUN
admet-425	139	15	and	and	CCONJ
admet-425	139	16	thus	thus	ADV
admet-425	139	17	affect	affect	VERB
admet-425	139	18	the	the	DET
admet-425	139	19	drug	drug	NOUN
admet-425	139	20	release	release	NOUN
admet-425	139	21	profile	profile	NOUN
admet-425	139	22	.	.	PUNCT
admet-425	140	1	therefore	therefore	ADV
admet-425	140	2	,	,	PUNCT
admet-425	140	3	the	the	DET
admet-425	140	4	conditions	condition	NOUN
admet-425	140	5	of	of	ADP
admet-425	140	6	separation	separation	NOUN
admet-425	140	7	procedure	procedure	NOUN
admet-425	140	8	should	should	AUX
admet-425	140	9	be	be	AUX
admet-425	140	10	clearly	clearly	ADV
admet-425	140	11	stated	state	VERB
admet-425	140	12	in	in	ADP
admet-425	140	13	the	the	DET
admet-425	140	14	published	publish	VERB
admet-425	140	15	results	result	NOUN
admet-425	140	16	.	.	PUNCT
admet-425	141	1	in	in	ADP
admet-425	141	2	(	(	PUNCT
admet-425	141	3	ultra)filtration	ultra)filtration	VERB
admet-425	141	4	the	the	DET
admet-425	141	5	adsorption	adsorption	NOUN
admet-425	141	6	of	of	ADP
admet-425	141	7	the	the	DET
admet-425	141	8	released	release	VERB
admet-425	141	9	drug	drug	NOUN
admet-425	141	10	to	to	ADP
admet-425	141	11	the	the	DET
admet-425	141	12	filter	filter	NOUN
admet-425	141	13	should	should	AUX
admet-425	141	14	be	be	AUX
admet-425	141	15	considered	consider	VERB
admet-425	141	16	.	.	PUNCT
admet-425	142	1	also	also	ADV
admet-425	142	2	,	,	PUNCT
admet-425	142	3	the	the	DET
admet-425	142	4	particles	particle	NOUN
admet-425	142	5	may	may	AUX
admet-425	142	6	clog	clog	VERB
admet-425	142	7	the	the	DET
admet-425	142	8	filter	filter	NOUN
admet-425	142	9	pores	pore	NOUN
admet-425	142	10	resulting	result	VERB
admet-425	142	11	in	in	ADP
admet-425	142	12	slow	slow	ADJ
admet-425	142	13	filtration	filtration	NOUN
admet-425	142	14	and	and	CCONJ
admet-425	142	15	limited	limited	ADJ
admet-425	142	16	volume	volume	NOUN
admet-425	142	17	of	of	ADP
admet-425	142	18	filtered	filter	VERB
admet-425	142	19	sample	sample	NOUN
admet-425	142	20	.	.	PUNCT
admet-425	143	1	another	another	DET
admet-425	143	2	disadvantage	disadvantage	NOUN
admet-425	143	3	of	of	ADP
admet-425	143	4	this	this	DET
admet-425	143	5	method	method	NOUN
admet-425	143	6	is	be	AUX
admet-425	143	7	the	the	DET
admet-425	143	8	loss	loss	NOUN
admet-425	143	9	of	of	ADP
admet-425	143	10	drug	drug	NOUN
admet-425	143	11	-	-	PUNCT
admet-425	143	12	loaded	load	VERB
admet-425	143	13	particles	particle	NOUN
admet-425	143	14	due	due	ADJ
admet-425	143	15	to	to	ADP
admet-425	143	16	sampling	sample	VERB
admet-425	143	17	,	,	PUNCT
admet-425	143	18	thereby	thereby	ADV
admet-425	143	19	resulting	result	VERB
admet-425	143	20	in	in	ADP
admet-425	143	21	an	an	DET
admet-425	143	22	incomplete	incomplete	ADJ
admet-425	143	23	drug	drug	NOUN
admet-425	143	24	release	release	NOUN
admet-425	143	25	profile	profile	NOUN
admet-425	143	26	.	.	PUNCT
admet-425	144	1	another	another	DET
admet-425	144	2	important	important	ADJ
admet-425	144	3	obstacle	obstacle	NOUN
admet-425	144	4	is	be	AUX
admet-425	144	5	aggregation	aggregation	NOUN
admet-425	144	6	of	of	ADP
admet-425	144	7	particles	particle	NOUN
admet-425	144	8	which	which	PRON
admet-425	144	9	may	may	AUX
admet-425	144	10	decrease	decrease	VERB
admet-425	144	11	the	the	DET
admet-425	144	12	release	release	NOUN
admet-425	144	13	rate	rate	NOUN
admet-425	144	14	.	.	PUNCT
admet-425	145	1	loss	loss	NOUN
admet-425	145	2	in	in	ADP
admet-425	145	3	volume	volume	NOUN
admet-425	145	4	because	because	SCONJ
admet-425	145	5	of	of	ADP
admet-425	145	6	filtration	filtration	NOUN
admet-425	145	7	during	during	ADP
admet-425	145	8	sampling	sample	VERB
admet-425	145	9	and	and	CCONJ
admet-425	145	10	buffer	buffer	NOUN
admet-425	145	11	replacement	replacement	NOUN
admet-425	145	12	is	be	AUX
admet-425	145	13	a	a	DET
admet-425	145	14	concern	concern	NOUN
admet-425	145	15	when	when	SCONJ
admet-425	145	16	the	the	DET
admet-425	145	17	amount	amount	NOUN
admet-425	145	18	of	of	ADP
admet-425	145	19	release	release	NOUN
admet-425	145	20	media	medium	NOUN
admet-425	145	21	is	be	AUX
admet-425	145	22	small	small	ADJ
admet-425	146	1	[	[	X
admet-425	146	2	75	75	NUM
admet-425	146	3	]	]	PUNCT
admet-425	146	4	.	.	PUNCT
admet-425	147	1	conclusions	conclusion	NOUN
admet-425	147	2	mucosal	mucosal	NOUN
admet-425	147	3	drug	drug	NOUN
admet-425	147	4	delivery	delivery	NOUN
admet-425	147	5	systems	system	NOUN
admet-425	147	6	differ	differ	VERB
admet-425	147	7	significantly	significantly	ADV
admet-425	147	8	in	in	ADP
admet-425	147	9	formulation	formulation	NOUN
admet-425	147	10	design	design	NOUN
admet-425	147	11	and	and	CCONJ
admet-425	147	12	their	their	PRON
admet-425	147	13	physicochemical	physicochemical	ADJ
admet-425	147	14	and	and	CCONJ
admet-425	147	15	release	release	NOUN
admet-425	147	16	characteristics	characteristic	NOUN
admet-425	147	17	.	.	PUNCT
admet-425	148	1	therefore	therefore	ADV
admet-425	148	2	versatile	versatile	ADV
admet-425	148	3	in	in	ADP
admet-425	148	4	vitro	vitro	X
admet-425	148	5	release	release	NOUN
admet-425	148	6	methods	method	NOUN
admet-425	148	7	are	be	AUX
admet-425	148	8	currently	currently	ADV
admet-425	148	9	used	use	VERB
admet-425	148	10	for	for	ADP
admet-425	148	11	their	their	PRON
admet-425	148	12	characterisation	characterisation	NOUN
admet-425	148	13	,	,	PUNCT
admet-425	148	14	considering	consider	VERB
admet-425	148	15	the	the	DET
admet-425	148	16	specific	specific	ADJ
admet-425	148	17	conditions	condition	NOUN
admet-425	148	18	at	at	ADP
admet-425	148	19	the	the	DET
admet-425	148	20	administration	administration	NOUN
admet-425	148	21	site	site	NOUN
admet-425	148	22	.	.	PUNCT
admet-425	149	1	compendial	compendial	ADJ
admet-425	149	2	methods	method	NOUN
admet-425	149	3	are	be	AUX
admet-425	149	4	used	use	VERB
admet-425	149	5	as	as	ADP
admet-425	149	6	a	a	DET
admet-425	149	7	first	first	ADJ
admet-425	149	8	approach	approach	NOUN
admet-425	149	9	in	in	ADP
admet-425	149	10	method	method	NOUN
admet-425	149	11	development	development	NOUN
admet-425	149	12	whenever	whenever	SCONJ
admet-425	149	13	applicable	applicable	ADJ
admet-425	149	14	.	.	PUNCT
admet-425	150	1	further	further	ADJ
admet-425	150	2	progress	progress	NOUN
admet-425	150	3	in	in	ADP
admet-425	150	4	this	this	DET
admet-425	150	5	field	field	NOUN
admet-425	150	6	is	be	AUX
admet-425	150	7	focused	focus	VERB
admet-425	150	8	towards	towards	ADP
admet-425	150	9	the	the	DET
admet-425	150	10	development	development	NOUN
admet-425	150	11	of	of	ADP
admet-425	150	12	novel	novel	ADJ
admet-425	150	13	biorelevant	biorelevant	NOUN
admet-425	150	14	methods	method	NOUN
admet-425	150	15	,	,	PUNCT
admet-425	150	16	which	which	PRON
admet-425	150	17	would	would	AUX
admet-425	150	18	be	be	AUX
admet-425	150	19	able	able	ADJ
admet-425	150	20	to	to	PART
admet-425	150	21	predict	predict	VERB
admet-425	150	22	more	more	ADJ
admet-425	150	23	mario	mario	PROPN
admet-425	150	24	jug	jug	PROPN
admet-425	150	25	et	et	PROPN
admet-425	150	26	al	al	PROPN
admet-425	150	27	.	.	PROPN
admet-425	150	28	admet	admet	PROPN
admet-425	150	29	&	&	CCONJ
admet-425	150	30	dmpk	dmpk	PROPN
admet-425	150	31	5(3	5(3	NUM
admet-425	150	32	)	)	PUNCT
admet-425	150	33	(	(	PUNCT
admet-425	150	34	2017	2017	NUM
admet-425	150	35	)	)	PUNCT
admet-425	150	36	173	173	NUM
admet-425	150	37	-	-	SYM
admet-425	150	38	182	182	NUM
admet-425	150	39	180	180	NUM
admet-425	150	40	closely	closely	ADV
admet-425	150	41	the	the	DET
admet-425	150	42	in	in	ADP
admet-425	150	43	vivo	vivo	ADJ
admet-425	150	44	performance	performance	NOUN
admet-425	150	45	of	of	ADP
admet-425	150	46	the	the	DET
admet-425	150	47	formulation	formulation	NOUN
admet-425	150	48	.	.	PUNCT
admet-425	151	1	acknowledgements	acknowledgement	NOUN
admet-425	151	2	:	:	PUNCT
admet-425	151	3	this	this	DET
admet-425	151	4	work	work	NOUN
admet-425	151	5	was	be	AUX
admet-425	151	6	supported	support	VERB
admet-425	151	7	by	by	ADP
admet-425	151	8	a	a	DET
admet-425	151	9	project	project	NOUN
admet-425	151	10	“	"	PUNCT
admet-425	151	11	modelling	modelling	NOUN
admet-425	151	12	of	of	ADP
admet-425	151	13	the	the	DET
admet-425	151	14	pharmaceutical	pharmaceutical	NOUN
admet-425	151	15	spray	spray	NOUN
admet-425	151	16	drying	dry	VERB
admet-425	151	17	process	process	NOUN
admet-425	151	18	of	of	ADP
admet-425	151	19	the	the	DET
admet-425	151	20	emulsions	emulsion	NOUN
admet-425	151	21	in	in	ADP
admet-425	151	22	laboratory	laboratory	NOUN
admet-425	151	23	and	and	CCONJ
admet-425	151	24	pilot	pilot	NOUN
admet-425	151	25	scale	scale	NOUN
admet-425	151	26	”	"	PUNCT
admet-425	151	27	in	in	ADP
admet-425	151	28	collaboration	collaboration	NOUN
admet-425	151	29	with	with	ADP
admet-425	151	30	the	the	DET
admet-425	151	31	industrial	industrial	ADJ
admet-425	151	32	partner	partner	NOUN
admet-425	151	33	pliva	pliva	PROPN
admet-425	151	34	croatia	croatia	PROPN
admet-425	151	35	ltd	ltd	PROPN
admet-425	151	36	.	.	PROPN
admet-425	151	37	references	reference	NOUN
admet-425	152	1	[	[	X
admet-425	152	2	1	1	NUM
admet-425	152	3	]	]	X
admet-425	152	4	c.k	c.k	PROPN
admet-425	152	5	.	.	PROPN
admet-425	152	6	brown	brown	PROPN
admet-425	152	7	,	,	PUNCT
admet-425	152	8	h.d	h.d	PROPN
admet-425	152	9	.	.	PROPN
admet-425	152	10	friedel	friedel	PROPN
admet-425	152	11	,	,	PUNCT
admet-425	152	12	a.r	a.r	PROPN
admet-425	152	13	.	.	PROPN
admet-425	152	14	barker	barker	PROPN
admet-425	152	15	,	,	PUNCT
admet-425	152	16	l.f	l.f	PROPN
admet-425	152	17	.	.	PROPN
admet-425	152	18	buhse	buhse	PROPN
admet-425	152	19	,	,	PUNCT
admet-425	152	20	s.	s.	PROPN
admet-425	152	21	keitel	keitel	PROPN
admet-425	152	22	,	,	PUNCT
admet-425	152	23	t.l	t.l	PROPN
admet-425	152	24	.	.	PROPN
admet-425	152	25	cecil	cecil	PROPN
admet-425	152	26	,	,	PUNCT
admet-425	152	27	j.	j.	PROPN
admet-425	152	28	kraemer	kraemer	PROPN
admet-425	152	29	,	,	PUNCT
admet-425	152	30	j.m	j.m	PROPN
admet-425	152	31	.	.	PROPN
admet-425	152	32	morris	morris	PROPN
admet-425	152	33	,	,	PUNCT
admet-425	152	34	c.	c.	PROPN
admet-425	152	35	reppas	reppas	PROPN
admet-425	152	36	,	,	PUNCT
admet-425	152	37	m.p	m.p	PROPN
admet-425	152	38	.	.	PROPN
admet-425	152	39	stickelmeyer	stickelmeyer	PROPN
admet-425	152	40	,	,	PUNCT
admet-425	152	41	c.	c.	PROPN
admet-425	152	42	yomota	yomota	PROPN
admet-425	152	43	,	,	PUNCT
admet-425	152	44	v.p	v.p	PROPN
admet-425	152	45	.	.	PROPN
admet-425	152	46	shah	shah	PROPN
admet-425	152	47	,	,	PUNCT
admet-425	152	48	aaps	aap	NOUN
admet-425	152	49	pharmscitech	pharmscitech	VERB
admet-425	152	50	12	12	NUM
admet-425	152	51	(	(	PUNCT
admet-425	152	52	2011	2011	NUM
admet-425	152	53	)	)	PUNCT
admet-425	153	1	782–794	782–794	NUM
admet-425	153	2	.	.	PUNCT
admet-425	154	1	[	[	X
admet-425	154	2	2	2	X
admet-425	154	3	]	]	PUNCT
admet-425	154	4	j.	j.	PROPN
admet-425	154	5	siepmann	siepmann	PROPN
admet-425	154	6	,	,	PUNCT
admet-425	154	7	f.	f.	PROPN
admet-425	154	8	siepmann	siepmann	PROPN
admet-425	154	9	,	,	PUNCT
admet-425	154	10	international	international	ADJ
admet-425	154	11	journal	journal	NOUN
admet-425	154	12	of	of	ADP
admet-425	154	13	pharmaceutics	pharmaceutic	NOUN
admet-425	154	14	453	453	NUM
admet-425	154	15	(	(	PUNCT
admet-425	154	16	2013	2013	NUM
admet-425	154	17	)	)	PUNCT
admet-425	154	18	12–24	12–24	NUM
admet-425	154	19	.	.	PUNCT
admet-425	155	1	[	[	X
admet-425	155	2	3	3	NUM
admet-425	155	3	]	]	PUNCT
admet-425	155	4	m.	m.	NOUN
admet-425	155	5	jug	jug	NOUN
admet-425	155	6	,	,	PUNCT
admet-425	155	7	a.	a.	PROPN
admet-425	155	8	hafner	hafner	PROPN
admet-425	155	9	,	,	PUNCT
admet-425	155	10	j.	j.	PROPN
admet-425	155	11	lovrić	lovrić	PROPN
admet-425	155	12	,	,	PUNCT
admet-425	155	13	m.	m.	PROPN
admet-425	155	14	lusina	lusina	PROPN
admet-425	155	15	kregar	kregar	PROPN
admet-425	155	16	,	,	PUNCT
admet-425	155	17	i.	i.	PROPN
admet-425	155	18	pepić	pepić	PROPN
admet-425	155	19	,	,	PUNCT
admet-425	155	20	ž	ž	PROPN
admet-425	155	21	.	.	PROPN
admet-425	155	22	vanić	vanić	PROPN
admet-425	155	23	,	,	PUNCT
admet-425	155	24	b.	b.	PROPN
admet-425	155	25	cetina	cetina	PROPN
admet-425	155	26	-	-	PUNCT
admet-425	155	27	čižmek	čižmek	PROPN
admet-425	155	28	,	,	PUNCT
admet-425	155	29	j.	j.	PROPN
admet-425	155	30	filipović	filipović	PROPN
admet-425	155	31	-	-	PUNCT
admet-425	155	32	grčić	grčić	PROPN
admet-425	155	33	,	,	PUNCT
admet-425	155	34	journal	journal	NOUN
admet-425	155	35	of	of	ADP
admet-425	155	36	pharmaceutical	pharmaceutical	NOUN
admet-425	155	37	and	and	CCONJ
admet-425	155	38	biomedical	biomedical	ADJ
admet-425	155	39	analysis	analysis	NOUN
admet-425	155	40	(	(	PUNCT
admet-425	155	41	2017	2017	NUM
admet-425	155	42	)	)	PUNCT
admet-425	155	43	doi	doi	NOUN
admet-425	155	44	:	:	PUNCT
admet-425	155	45	http://dx.doi.org/10.1016/j.jpba.2017.06.072	http://dx.doi.org/10.1016/j.jpba.2017.06.072	NOUN
admet-425	155	46	.	.	PUNCT
admet-425	156	1	[	[	X
admet-425	156	2	4	4	X
admet-425	156	3	]	]	PUNCT
admet-425	156	4	j.	j.	PROPN
admet-425	156	5	shen	shen	PROPN
admet-425	156	6	,	,	PUNCT
admet-425	156	7	d.j	d.j	PROPN
admet-425	156	8	.	.	PROPN
admet-425	156	9	burgess	burgess	PROPN
admet-425	156	10	,	,	PUNCT
admet-425	156	11	journal	journal	NOUN
admet-425	156	12	of	of	ADP
admet-425	156	13	controlled	control	VERB
admet-425	156	14	release	release	NOUN
admet-425	156	15	219	219	NUM
admet-425	156	16	(	(	PUNCT
admet-425	156	17	2015	2015	NUM
admet-425	156	18	)	)	PUNCT
admet-425	156	19	644–651	644–651	NUM
admet-425	156	20	.	.	PUNCT
admet-425	157	1	[	[	X
admet-425	157	2	5	5	NUM
admet-425	157	3	]	]	PUNCT
admet-425	157	4	m.	m.	NOUN
admet-425	157	5	siewert	siewert	PROPN
admet-425	157	6	,	,	PUNCT
admet-425	157	7	j.	j.	PROPN
admet-425	157	8	dressman	dressman	PROPN
admet-425	157	9	,	,	PUNCT
admet-425	157	10	c.k	c.k	PROPN
admet-425	157	11	.	.	PROPN
admet-425	157	12	brown	brown	PROPN
admet-425	157	13	,	,	PUNCT
admet-425	157	14	v.p	v.p	PROPN
admet-425	157	15	.	.	PROPN
admet-425	157	16	shah	shah	PROPN
admet-425	157	17	,	,	PUNCT
admet-425	157	18	j.-m	j.-m	PROPN
admet-425	157	19	.	.	PUNCT
admet-425	158	1	aiache	aiache	PROPN
admet-425	158	2	,	,	PUNCT
admet-425	158	3	n.	n.	PROPN
admet-425	158	4	aoyagi	aoyagi	PROPN
admet-425	158	5	,	,	PUNCT
admet-425	158	6	d.	d.	PROPN
admet-425	158	7	bashaw	bashaw	PROPN
admet-425	158	8	,	,	PUNCT
admet-425	158	9	c.	c.	PROPN
admet-425	158	10	brown	brown	PROPN
admet-425	158	11	,	,	PUNCT
admet-425	158	12	w.	w.	PROPN
admet-425	158	13	brown	brown	PROPN
admet-425	158	14	,	,	PUNCT
admet-425	158	15	d.	d.	PROPN
admet-425	158	16	burgess	burgess	PROPN
admet-425	158	17	,	,	PUNCT
admet-425	158	18	j.	j.	PROPN
admet-425	158	19	crison	crison	PROPN
admet-425	158	20	,	,	PUNCT
admet-425	158	21	p.	p.	PROPN
admet-425	158	22	deluca	deluca	PROPN
admet-425	158	23	,	,	PUNCT
admet-425	158	24	r.	r.	PROPN
admet-425	158	25	djerki	djerki	PROPN
admet-425	158	26	,	,	PUNCT
admet-425	158	27	j.	j.	PROPN
admet-425	158	28	dressman	dressman	PROPN
admet-425	158	29	,	,	PUNCT
admet-425	158	30	t.	t.	PROPN
admet-425	158	31	foster	foster	PROPN
admet-425	158	32	,	,	PUNCT
admet-425	158	33	k.	k.	PROPN
admet-425	158	34	gjellan	gjellan	PROPN
admet-425	158	35	,	,	PUNCT
admet-425	158	36	v.	v.	ADP
admet-425	158	37	gray	gray	ADJ
admet-425	158	38	,	,	PUNCT
admet-425	158	39	a.	a.	NOUN
admet-425	158	40	hussain	hussain	PROPN
admet-425	158	41	,	,	PUNCT
admet-425	158	42	t.	t.	NOUN
admet-425	158	43	ingallinera	ingallinera	NOUN
admet-425	158	44	,	,	PUNCT
admet-425	158	45	j.	j.	PROPN
admet-425	158	46	klancke	klancke	PROPN
admet-425	158	47	,	,	PUNCT
admet-425	158	48	j.	j.	PROPN
admet-425	158	49	kraemer	kraemer	PROPN
admet-425	158	50	,	,	PUNCT
admet-425	158	51	h.	h.	PROPN
admet-425	158	52	kristensen	kristensen	PROPN
admet-425	158	53	,	,	PUNCT
admet-425	158	54	k.	k.	PROPN
admet-425	158	55	kumi	kumi	PROPN
admet-425	158	56	,	,	PUNCT
admet-425	158	57	c.	c.	PROPN
admet-425	158	58	leuner	leuner	PROPN
admet-425	158	59	,	,	PUNCT
admet-425	158	60	j.	j.	PROPN
admet-425	158	61	limberg	limberg	PROPN
admet-425	158	62	,	,	PUNCT
admet-425	158	63	p.	p.	NOUN
admet-425	158	64	loos	loos	PROPN
admet-425	158	65	,	,	PUNCT
admet-425	158	66	l.	l.	PROPN
admet-425	158	67	margulis	margulis	PROPN
admet-425	158	68	,	,	PUNCT
admet-425	158	69	p.	p.	NOUN
admet-425	158	70	marroum	marroum	PROPN
admet-425	158	71	,	,	PUNCT
admet-425	158	72	h.	h.	PROPN
admet-425	158	73	moeller	moeller	PROPN
admet-425	158	74	,	,	PUNCT
admet-425	158	75	b.	b.	PROPN
admet-425	158	76	mueller	mueller	PROPN
admet-425	158	77	,	,	PUNCT
admet-425	158	78	m.	m.	NOUN
admet-425	158	79	mueller	mueller	PROPN
admet-425	158	80	-	-	PUNCT
admet-425	158	81	zsigmondy	zsigmondy	PROPN
admet-425	158	82	,	,	PUNCT
admet-425	158	83	n.	n.	PROPN
admet-425	158	84	okafo	okafo	PROPN
admet-425	158	85	,	,	PUNCT
admet-425	158	86	l.	l.	PROPN
admet-425	158	87	ouderkirk	ouderkirk	PROPN
admet-425	158	88	,	,	PUNCT
admet-425	158	89	s.	s.	PROPN
admet-425	158	90	parsi	parsi	PROPN
admet-425	158	91	,	,	PUNCT
admet-425	158	92	s.	s.	PROPN
admet-425	158	93	qureshi	qureshi	PROPN
admet-425	158	94	,	,	PUNCT
admet-425	158	95	j.	j.	PROPN
admet-425	158	96	robinson	robinson	PROPN
admet-425	158	97	,	,	PUNCT
admet-425	158	98	v.	v.	ADP
admet-425	158	99	shah	shah	PROPN
admet-425	158	100	,	,	PUNCT
admet-425	158	101	m.	m.	NOUN
admet-425	158	102	siewert	siewert	PROPN
admet-425	158	103	,	,	PUNCT
admet-425	158	104	r.	r.	PROPN
admet-425	158	105	uppoor	uppoor	PROPN
admet-425	158	106	,	,	PUNCT
admet-425	158	107	r.	r.	PROPN
admet-425	158	108	williams	williams	PROPN
admet-425	158	109	,	,	PUNCT
admet-425	158	110	aaps	aap	NOUN
admet-425	158	111	pharmscitech	pharmscitech	VERB
admet-425	158	112	4	4	NUM
admet-425	158	113	(	(	PUNCT
admet-425	158	114	2003	2003	NUM
admet-425	158	115	)	)	PUNCT
admet-425	158	116	43–52	43–52	NUM
admet-425	158	117	.	.	PUNCT
admet-425	159	1	[	[	X
admet-425	159	2	6	6	NUM
admet-425	159	3	]	]	PUNCT
admet-425	159	4	usp	usp	NOUN
admet-425	159	5	<	<	X
admet-425	159	6	1724	1724	NUM
admet-425	159	7	>	>	X
admet-425	159	8	in	in	ADP
admet-425	159	9	:	:	PUNCT
admet-425	159	10	,	,	PUNCT
admet-425	159	11	united	united	PROPN
admet-425	159	12	states	states	PROPN
admet-425	159	13	pharmacopeia	pharmacopeia	PROPN
admet-425	159	14	usp	usp	PROPN
admet-425	159	15	40	40	NUM
admet-425	159	16	/	/	SYM
admet-425	159	17	nf	nf	NOUN
admet-425	159	18	35	35	NUM
admet-425	159	19	,	,	PUNCT
admet-425	159	20	the	the	DET
admet-425	159	21	united	united	PROPN
admet-425	159	22	states	states	PROPN
admet-425	159	23	pharmacopeial	pharmacopeial	ADJ
admet-425	159	24	convention	convention	PROPN
admet-425	159	25	,	,	PUNCT
admet-425	159	26	rockville	rockville	PROPN
admet-425	159	27	,	,	PUNCT
admet-425	159	28	usa	usa	PROPN
admet-425	159	29	,	,	PUNCT
admet-425	159	30	2017	2017	NUM
admet-425	159	31	,	,	PUNCT
admet-425	159	32	pp	pp	ADJ
admet-425	159	33	.	.	PUNCT
admet-425	159	34	2055–2067	2055–2067	NUM
admet-425	159	35	.	.	PUNCT
admet-425	160	1	[	[	X
admet-425	160	2	7	7	X
admet-425	160	3	]	]	X
admet-425	160	4	fda	fda	PROPN
admet-425	160	5	dissolution	dissolution	PROPN
admet-425	160	6	methods	method	NOUN
admet-425	160	7	database	database	NOUN
admet-425	160	8	,	,	PUNCT
admet-425	160	9	https://www.accessdata.fda.gov/scripts/cder/dissolution/index.cfm	https://www.accessdata.fda.gov/scripts/cder/dissolution/index.cfm	PROPN
admet-425	160	10	.	.	PUNCT
admet-425	161	1	(	(	PUNCT
admet-425	161	2	accessed	access	VERB
admet-425	161	3	17	17	NUM
admet-425	161	4	march	march	NOUN
admet-425	161	5	2017	2017	NUM
admet-425	161	6	)	)	PUNCT
admet-425	161	7	.	.	PUNCT
admet-425	162	1	[	[	X
admet-425	162	2	8	8	X
admet-425	162	3	]	]	PUNCT
admet-425	162	4	usp	usp	NOUN
admet-425	162	5	<	<	X
admet-425	162	6	1004	1004	NUM
admet-425	162	7	>	>	X
admet-425	162	8	in	in	ADP
admet-425	162	9	:	:	PUNCT
admet-425	162	10	,	,	PUNCT
admet-425	162	11	united	united	PROPN
admet-425	162	12	states	states	PROPN
admet-425	162	13	pharmacopeia	pharmacopeia	PROPN
admet-425	162	14	usp	usp	PROPN
admet-425	162	15	40	40	NUM
admet-425	162	16	/	/	SYM
admet-425	162	17	nf	nf	NOUN
admet-425	162	18	35	35	NUM
admet-425	162	19	,	,	PUNCT
admet-425	162	20	the	the	DET
admet-425	162	21	united	united	PROPN
admet-425	162	22	states	states	PROPN
admet-425	162	23	pharmacopeial	pharmacopeial	ADJ
admet-425	162	24	convention	convention	PROPN
admet-425	162	25	,	,	PUNCT
admet-425	162	26	rockville	rockville	PROPN
admet-425	162	27	,	,	PUNCT
admet-425	162	28	usa	usa	PROPN
admet-425	162	29	,	,	PUNCT
admet-425	162	30	2017	2017	NUM
admet-425	162	31	,	,	PUNCT
admet-425	162	32	pp	pp	ADJ
admet-425	162	33	.	.	PUNCT
admet-425	163	1	829–832	829–832	NUM
admet-425	163	2	.	.	PUNCT
admet-425	164	1	[	[	X
admet-425	164	2	9	9	NUM
admet-425	164	3	]	]	PUNCT
admet-425	164	4	usp	usp	NOUN
admet-425	164	5	<	<	X
admet-425	164	6	724	724	NUM
admet-425	164	7	>	>	X
admet-425	164	8	in	in	ADP
admet-425	164	9	:	:	PUNCT
admet-425	164	10	,	,	PUNCT
admet-425	164	11	united	united	PROPN
admet-425	164	12	states	states	PROPN
admet-425	164	13	pharmacopeia	pharmacopeia	PROPN
admet-425	164	14	usp	usp	PROPN
admet-425	164	15	40	40	NUM
admet-425	164	16	/	/	SYM
admet-425	164	17	nf	nf	NOUN
admet-425	164	18	35	35	NUM
admet-425	164	19	,	,	PUNCT
admet-425	164	20	the	the	DET
admet-425	164	21	united	united	PROPN
admet-425	164	22	states	states	PROPN
admet-425	164	23	pharmacopeial	pharmacopeial	ADJ
admet-425	164	24	convention	convention	PROPN
admet-425	164	25	,	,	PUNCT
admet-425	164	26	rockville	rockville	PROPN
admet-425	164	27	,	,	PUNCT
admet-425	164	28	usa	usa	PROPN
admet-425	164	29	,	,	PUNCT
admet-425	164	30	2017	2017	NUM
admet-425	164	31	,	,	PUNCT
admet-425	164	32	pp	pp	ADV
admet-425	164	33	.	.	PUNCT
admet-425	165	1	600–607	600–607	NUM
admet-425	165	2	.	.	PUNCT
admet-425	166	1	[	[	X
admet-425	166	2	10	10	NUM
admet-425	166	3	]	]	X
admet-425	166	4	ph	ph	PROPN
admet-425	166	5	.	.	PROPN
admet-425	166	6	eur	eur	PROPN
admet-425	166	7	.	.	PUNCT
admet-425	167	1	2.9.4	2.9.4	NUM
admet-425	167	2	.	.	PUNCT
admet-425	168	1	in	in	ADP
admet-425	168	2	:	:	PUNCT
admet-425	168	3	,	,	PUNCT
admet-425	168	4	european	european	PROPN
admet-425	168	5	pharmacopeia	pharmacopeia	PROPN
admet-425	168	6	9.0	9.0	NUM
admet-425	168	7	,	,	PUNCT
admet-425	168	8	european	european	ADJ
admet-425	168	9	directorate	directorate	NOUN
admet-425	168	10	for	for	ADP
admet-425	168	11	the	the	DET
admet-425	168	12	quality	quality	NOUN
admet-425	168	13	of	of	ADP
admet-425	168	14	medicines	medicine	NOUN
admet-425	168	15	and	and	CCONJ
admet-425	168	16	healthcare	healthcare	NOUN
admet-425	168	17	,	,	PUNCT
admet-425	168	18	strasbourg	strasbourg	PROPN
admet-425	168	19	,	,	PUNCT
admet-425	168	20	france	france	PROPN
admet-425	168	21	,	,	PUNCT
admet-425	168	22	2017	2017	NUM
admet-425	168	23	,	,	PUNCT
admet-425	168	24	pp	pp	ADJ
admet-425	168	25	.	.	PUNCT
admet-425	169	1	309–311	309–311	NUM
admet-425	169	2	.	.	PUNCT
admet-425	170	1	[	[	X
admet-425	170	2	11	11	NUM
admet-425	170	3	]	]	PUNCT
admet-425	170	4	usp	usp	NOUN
admet-425	170	5	dissolution	dissolution	PROPN
admet-425	170	6	methods	method	NOUN
admet-425	170	7	database	database	NOUN
admet-425	170	8	,	,	PUNCT
admet-425	170	9	http://www.usp.org/usp-nf/overview/compendial-tools/uspdissolution-methods-database	http://www.usp.org/usp-nf/overview/compendial-tools/uspdissolution-methods-database	PROPN
admet-425	170	10	(	(	PUNCT
admet-425	170	11	accessed	access	VERB
admet-425	170	12	8	8	NUM
admet-425	170	13	march	march	NOUN
admet-425	170	14	2017	2017	NUM
admet-425	170	15	)	)	PUNCT
admet-425	171	1	[	[	X
admet-425	171	2	12	12	NUM
admet-425	171	3	]	]	PUNCT
admet-425	171	4	ph	ph	PROPN
admet-425	171	5	.	.	PROPN
admet-425	171	6	eur	eur	PROPN
admet-425	171	7	.	.	PUNCT
admet-425	171	8	2.9.25	2.9.25	NUM
admet-425	171	9	.	.	PUNCT
admet-425	172	1	in	in	ADP
admet-425	172	2	:	:	PUNCT
admet-425	172	3	,	,	PUNCT
admet-425	172	4	eur	eur	PROPN
admet-425	172	5	.	.	PUNCT
admet-425	172	6	pharmacop	pharmacop	NOUN
admet-425	172	7	.	.	PUNCT
admet-425	173	1	9.0	9.0	NUM
admet-425	173	2	,	,	PUNCT
admet-425	173	3	european	european	ADJ
admet-425	173	4	directorate	directorate	NOUN
admet-425	173	5	for	for	ADP
admet-425	173	6	the	the	DET
admet-425	173	7	quality	quality	NOUN
admet-425	173	8	of	of	ADP
admet-425	173	9	medicines	medicine	NOUN
admet-425	173	10	and	and	CCONJ
admet-425	173	11	healthcare	healthcare	NOUN
admet-425	173	12	,	,	PUNCT
admet-425	173	13	strasbourg	strasbourg	PROPN
admet-425	173	14	,	,	PUNCT
admet-425	173	15	france	france	PROPN
admet-425	173	16	,	,	PUNCT
admet-425	173	17	2017	2017	NUM
admet-425	173	18	,	,	PUNCT
admet-425	173	19	pp	pp	ADJ
admet-425	173	20	.	.	PUNCT
admet-425	174	1	340–344	340–344	NUM
admet-425	174	2	.	.	PUNCT
admet-425	175	1	[	[	X
admet-425	175	2	13	13	NUM
admet-425	175	3	]	]	SYM
admet-425	175	4	ph	ph	PROPN
admet-425	175	5	.	.	PROPN
admet-425	175	6	eur	eur	PROPN
admet-425	175	7	.	.	PUNCT
admet-425	176	1	2.9.42	2.9.42	NUM
admet-425	176	2	.	.	PUNCT
admet-425	177	1	in	in	ADP
admet-425	177	2	:	:	PUNCT
admet-425	177	3	,	,	PUNCT
admet-425	177	4	eur	eur	PROPN
admet-425	177	5	.	.	PUNCT
admet-425	177	6	pharmacop	pharmacop	NOUN
admet-425	177	7	.	.	PUNCT
admet-425	178	1	9.0	9.0	NUM
admet-425	178	2	,	,	PUNCT
admet-425	178	3	european	european	ADJ
admet-425	178	4	directorate	directorate	NOUN
admet-425	178	5	for	for	ADP
admet-425	178	6	the	the	DET
admet-425	178	7	quality	quality	NOUN
admet-425	178	8	of	of	ADP
admet-425	178	9	medicines	medicine	NOUN
admet-425	178	10	and	and	CCONJ
admet-425	178	11	healthcare	healthcare	NOUN
admet-425	178	12	,	,	PUNCT
admet-425	178	13	strasbourg	strasbourg	PROPN
admet-425	178	14	,	,	PUNCT
admet-425	178	15	france	france	PROPN
admet-425	178	16	,	,	PUNCT
admet-425	178	17	2017	2017	NUM
admet-425	178	18	,	,	PUNCT
admet-425	178	19	p.	p.	NOUN
admet-425	178	20	377	377	NUM
admet-425	178	21	.	.	PUNCT
admet-425	179	1	[	[	X
admet-425	179	2	14	14	NUM
admet-425	179	3	]	]	PUNCT
admet-425	179	4	a.	a.	NOUN
admet-425	179	5	olejnik	olejnik	PROPN
admet-425	179	6	,	,	PUNCT
admet-425	179	7	j.	j.	PROPN
admet-425	179	8	goscianska	goscianska	PROPN
admet-425	179	9	,	,	PUNCT
admet-425	179	10	i.	i.	PROPN
admet-425	179	11	nowak	nowak	PROPN
admet-425	179	12	,	,	PUNCT
admet-425	179	13	journal	journal	NOUN
admet-425	179	14	of	of	ADP
admet-425	179	15	pharmaceutical	pharmaceutical	ADJ
admet-425	179	16	sciences	science	NOUN
admet-425	179	17	101	101	NUM
admet-425	179	18	(	(	PUNCT
admet-425	179	19	2012	2012	NUM
admet-425	179	20	)	)	PUNCT
admet-425	179	21	4032–4045	4032–4045	NUM
admet-425	179	22	.	.	PUNCT
admet-425	180	1	[	[	X
admet-425	180	2	15	15	NUM
admet-425	180	3	]	]	X
admet-425	180	4	g.l	g.l	PROPN
admet-425	180	5	.	.	PROPN
admet-425	180	6	flynn	flynn	PROPN
admet-425	180	7	,	,	PUNCT
admet-425	180	8	v.p	v.p	PROPN
admet-425	180	9	.	.	PROPN
admet-425	180	10	shah	shah	PROPN
admet-425	180	11	,	,	PUNCT
admet-425	180	12	s.n	s.n	PROPN
admet-425	180	13	.	.	PROPN
admet-425	180	14	tenjarla	tenjarla	PROPN
admet-425	180	15	,	,	PUNCT
admet-425	180	16	m.	m.	NOUN
admet-425	180	17	corbo	corbo	PROPN
admet-425	180	18	,	,	PUNCT
admet-425	180	19	d.	d.	PROPN
admet-425	180	20	demagistris	demagistris	PROPN
admet-425	180	21	,	,	PUNCT
admet-425	180	22	t.g	t.g	PROPN
admet-425	180	23	.	.	PROPN
admet-425	180	24	feldman	feldman	PROPN
admet-425	180	25	,	,	PUNCT
admet-425	180	26	t.j	t.j	PROPN
admet-425	180	27	.	.	PROPN
admet-425	180	28	franz	franz	PROPN
admet-425	180	29	,	,	PUNCT
admet-425	180	30	d.r	d.r	PROPN
admet-425	180	31	.	.	PROPN
admet-425	180	32	miran	miran	PROPN
admet-425	180	33	,	,	PUNCT
admet-425	180	34	d.m	d.m	PROPN
admet-425	180	35	.	.	PROPN
admet-425	180	36	pearce	pearce	PROPN
admet-425	180	37	,	,	PUNCT
admet-425	180	38	j.a	j.a	PROPN
admet-425	180	39	.	.	PROPN
admet-425	180	40	sequeira	sequeira	PROPN
admet-425	180	41	,	,	PUNCT
admet-425	180	42	j.	j.	PROPN
admet-425	180	43	swarbrick	swarbrick	PROPN
admet-425	180	44	,	,	PUNCT
admet-425	180	45	j.c.t	j.c.t	PROPN
admet-425	180	46	.	.	PUNCT
admet-425	180	47	wang	wang	PROPN
admet-425	180	48	,	,	PUNCT
admet-425	180	49	a.	a.	PROPN
admet-425	180	50	yacobi	yacobi	PROPN
admet-425	180	51	,	,	PUNCT
admet-425	180	52	j.l	j.l	PROPN
admet-425	180	53	.	.	PROPN
admet-425	180	54	zatz	zatz	PROPN
admet-425	180	55	,	,	PUNCT
admet-425	180	56	pharmaceutical	pharmaceutical	ADJ
admet-425	180	57	research	research	NOUN
admet-425	180	58	16	16	NUM
admet-425	180	59	(	(	PUNCT
admet-425	180	60	1999	1999	NUM
admet-425	180	61	)	)	PUNCT
admet-425	180	62	1325–1330	1325–1330	NUM
admet-425	180	63	.	.	PUNCT
admet-425	181	1	[	[	X
admet-425	181	2	16	16	NUM
admet-425	181	3	]	]	PUNCT
admet-425	181	4	p.	p.	PROPN
admet-425	181	5	zhang	zhang	PROPN
admet-425	181	6	,	,	PUNCT
admet-425	181	7	x.	x.	PROPN
admet-425	181	8	liu	liu	PROPN
admet-425	181	9	,	,	PUNCT
admet-425	181	10	w.	w.	PROPN
admet-425	181	11	hu	hu	PROPN
admet-425	181	12	,	,	PUNCT
admet-425	181	13	y.	y.	PROPN
admet-425	181	14	bai	bai	PROPN
admet-425	181	15	,	,	PUNCT
admet-425	181	16	l.	l.	PROPN
admet-425	181	17	zhang	zhang	PROPN
admet-425	181	18	,	,	PUNCT
admet-425	181	19	carbohydrate	carbohydrate	VERB
admet-425	181	20	polymers	polymer	NOUN
admet-425	181	21	149	149	NUM
admet-425	181	22	(	(	PUNCT
admet-425	181	23	2016	2016	NUM
admet-425	181	24	)	)	PUNCT
admet-425	181	25	224–230	224–230	NUM
admet-425	181	26	.	.	PUNCT
admet-425	182	1	[	[	X
admet-425	182	2	17	17	NUM
admet-425	182	3	]	]	X
admet-425	182	4	s.	s.	PROPN
admet-425	182	5	maiti	maiti	PROPN
admet-425	182	6	,	,	PUNCT
admet-425	182	7	a.	a.	NOUN
admet-425	182	8	chakravorty	chakravorty	NOUN
admet-425	182	9	,	,	PUNCT
admet-425	182	10	m.	m.	NOUN
admet-425	182	11	chowdhury	chowdhury	PROPN
admet-425	182	12	,	,	PUNCT
admet-425	182	13	international	international	ADJ
admet-425	182	14	journal	journal	NOUN
admet-425	182	15	of	of	ADP
admet-425	182	16	biological	biological	ADJ
admet-425	182	17	macromolecules	macromolecule	NOUN
admet-425	182	18	68	68	NUM
admet-425	182	19	(	(	PUNCT
admet-425	182	20	2014	2014	NUM
admet-425	182	21	)	)	PUNCT
admet-425	182	22	241–246	241–246	NUM
admet-425	182	23	.	.	PUNCT
admet-425	183	1	[	[	X
admet-425	183	2	18	18	NUM
admet-425	183	3	]	]	X
admet-425	183	4	c.	c.	PROPN
admet-425	183	5	karavasili	karavasili	PROPN
admet-425	183	6	,	,	PUNCT
admet-425	183	7	n.	n.	PROPN
admet-425	183	8	bouropoulos	bouropoulos	PROPN
admet-425	183	9	,	,	PUNCT
admet-425	183	10	l.	l.	PROPN
admet-425	183	11	sygellou	sygellou	PROPN
admet-425	183	12	,	,	PUNCT
admet-425	183	13	e.p	e.p	PROPN
admet-425	183	14	.	.	PROPN
admet-425	183	15	amanatiadou	amanatiadou	PROPN
admet-425	183	16	,	,	PUNCT
admet-425	183	17	i.s	i.s	PROPN
admet-425	183	18	.	.	PROPN
admet-425	183	19	vizirianakis	vizirianakis	PROPN
admet-425	183	20	,	,	PUNCT
admet-425	183	21	d.g	d.g	PROPN
admet-425	183	22	.	.	PROPN
admet-425	183	23	fatouros	fatouro	NOUN
admet-425	183	24	,	,	PUNCT
admet-425	183	25	material	material	NOUN
admet-425	183	26	science	science	NOUN
admet-425	183	27	and	and	CCONJ
admet-425	183	28	engineering	engineering	NOUN
admet-425	183	29	:	:	PUNCT
admet-425	183	30	c	c	NOUN
admet-425	183	31	59	59	NUM
admet-425	183	32	(	(	PUNCT
admet-425	183	33	2016	2016	NUM
admet-425	183	34	)	)	PUNCT
admet-425	183	35	1053–1062	1053–1062	NUM
admet-425	183	36	.	.	PUNCT
admet-425	184	1	[	[	X
admet-425	184	2	19	19	NUM
admet-425	184	3	]	]	X
admet-425	184	4	s.	s.	PROPN
admet-425	184	5	lungare	lungare	PROPN
admet-425	184	6	,	,	PUNCT
admet-425	184	7	j.	j.	PROPN
admet-425	184	8	bowen	bowen	PROPN
admet-425	184	9	,	,	PUNCT
admet-425	184	10	r.	r.	PROPN
admet-425	184	11	badhan	badhan	PROPN
admet-425	184	12	,	,	PUNCT
admet-425	184	13	journal	journal	NOUN
admet-425	184	14	of	of	ADP
admet-425	184	15	pharmaceutical	pharmaceutical	PROPN
admet-425	184	16	sciences	science	NOUN
admet-425	184	17	105	105	NUM
admet-425	184	18	(	(	PUNCT
admet-425	184	19	2016	2016	NUM
admet-425	184	20	)	)	PUNCT
admet-425	184	21	1209–1220	1209–1220	NUM
admet-425	184	22	.	.	PUNCT
admet-425	185	1	[	[	X
admet-425	185	2	20	20	NUM
admet-425	185	3	]	]	X
admet-425	185	4	c.	c.	PROPN
admet-425	185	5	li	li	PROPN
admet-425	185	6	,	,	PUNCT
admet-425	185	7	c.	c.	PROPN
admet-425	185	8	li	li	PROPN
admet-425	185	9	,	,	PUNCT
admet-425	185	10	z.	z.	PROPN
admet-425	185	11	liu	liu	PROPN
admet-425	185	12	,	,	PUNCT
admet-425	185	13	q.	q.	PROPN
admet-425	185	14	li	li	PROPN
admet-425	185	15	,	,	PUNCT
admet-425	185	16	x.	x.	PROPN
admet-425	185	17	yan	yan	PROPN
admet-425	185	18	,	,	PUNCT
admet-425	185	19	y.	y.	PROPN
admet-425	185	20	liu	liu	PROPN
admet-425	185	21	,	,	PUNCT
admet-425	185	22	w.	w.	PROPN
admet-425	185	23	lu	lu	PROPN
admet-425	185	24	,	,	PUNCT
admet-425	185	25	international	international	ADJ
admet-425	185	26	journal	journal	NOUN
admet-425	185	27	of	of	ADP
admet-425	185	28	pharmaceutics	pharmaceutic	NOUN
admet-425	185	29	474	474	NUM
admet-425	185	30	(	(	PUNCT
admet-425	185	31	2014	2014	NUM
admet-425	185	32	)	)	PUNCT
admet-425	185	33	123	123	NUM
admet-425	185	34	–	–	PUNCT
admet-425	185	35	133	133	NUM
admet-425	185	36	.	.	PUNCT
admet-425	185	37	http://dx.doi.org/10.1016/j.jpba.2017.06.072	http://dx.doi.org/10.1016/j.jpba.2017.06.072	NOUN
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admet-425	185	39	http://www.usp.org/usp-nf/overview/compendial-tools/usp-dissolution-methods-database	http://www.usp.org/usp-nf/overview/compendial-tools/usp-dissolution-methods-database	PROPN
admet-425	185	40	http://www.usp.org/usp-nf/overview/compendial-tools/usp-dissolution-methods-database	http://www.usp.org/usp-nf/overview/compendial-tools/usp-dissolution-methods-database	PROPN
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admet-425	185	42	&	&	CCONJ
admet-425	185	43	dmpk	dmpk	PROPN
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admet-425	185	45	)	)	PUNCT
admet-425	185	46	(	(	PUNCT
admet-425	185	47	2017	2017	NUM
admet-425	185	48	)	)	PUNCT
admet-425	185	49	173	173	NUM
admet-425	185	50	-	-	SYM
admet-425	185	51	182	182	NUM
admet-425	185	52	in	in	ADP
admet-425	185	53	vitro	vitro	X
admet-425	185	54	release	release	NOUN
admet-425	185	55	testing	testing	NOUN
admet-425	185	56	of	of	ADP
admet-425	185	57	mucosal	mucosal	ADJ
admet-425	185	58	drug	drug	NOUN
admet-425	185	59	delivery	delivery	NOUN
admet-425	185	60	systems	system	NOUN
admet-425	185	61	doi	doi	NOUN
admet-425	185	62	:	:	PUNCT
admet-425	185	63	10.5599	10.5599	NUM
admet-425	185	64	/	/	SYM
admet-425	185	65	admet.5.3.425	admet.5.3.425	NUM
admet-425	185	66	181	181	NUM
admet-425	186	1	[	[	X
admet-425	186	2	21	21	NUM
admet-425	186	3	]	]	PUNCT
admet-425	186	4	a.	a.	PROPN
admet-425	186	5	miro	miro	PROPN
admet-425	186	6	,	,	PUNCT
admet-425	186	7	i.	i.	PROPN
admet-425	186	8	d’angelo	d’angelo	PROPN
admet-425	186	9	,	,	PUNCT
admet-425	186	10	a.	a.	NOUN
admet-425	186	11	nappi	nappi	PROPN
admet-425	186	12	,	,	PUNCT
admet-425	186	13	p.	p.	PROPN
admet-425	186	14	la	la	PROPN
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admet-425	186	16	,	,	PUNCT
admet-425	186	17	m.	m.	NOUN
admet-425	186	18	biondi	biondi	PROPN
admet-425	186	19	,	,	PUNCT
admet-425	186	20	l.	l.	PROPN
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admet-425	186	22	,	,	PUNCT
admet-425	186	23	p.	p.	PROPN
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admet-425	186	25	,	,	PUNCT
admet-425	186	26	r.	r.	PROPN
admet-425	186	27	russo	russo	PROPN
admet-425	186	28	,	,	PUNCT
admet-425	186	29	m.i	m.i	PROPN
admet-425	186	30	.	.	PROPN
admet-425	186	31	la	la	PROPN
admet-425	186	32	rotonda	rotonda	PROPN
admet-425	186	33	,	,	PUNCT
admet-425	186	34	f.	f.	PROPN
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admet-425	186	36	,	,	PUNCT
admet-425	186	37	f.	f.	PROPN
admet-425	186	38	quaglia	quaglia	PROPN
admet-425	186	39	,	,	PUNCT
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admet-425	186	41	journal	journal	NOUN
admet-425	186	42	of	of	ADP
admet-425	186	43	pharmaceutics	pharmaceutic	NOUN
admet-425	186	44	452	452	NUM
admet-425	186	45	(	(	PUNCT
admet-425	186	46	2013	2013	NUM
admet-425	186	47	)	)	PUNCT
admet-425	186	48	283–291	283–291	NUM
admet-425	186	49	.	.	PUNCT
admet-425	187	1	[	[	X
admet-425	187	2	22	22	NUM
admet-425	187	3	]	]	SYM
admet-425	187	4	a.b	a.b	PROPN
admet-425	187	5	.	.	PROPN
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admet-425	187	8	r.	r.	PROPN
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admet-425	187	10	,	,	PUNCT
admet-425	187	11	s.	s.	PROPN
admet-425	187	12	harsha	harsha	PROPN
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admet-425	187	16	,	,	PUNCT
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admet-425	187	22	,	,	PUNCT
admet-425	187	23	i.a	i.a	PROPN
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admet-425	187	26	,	,	PUNCT
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admet-425	187	32	(	(	PUNCT
admet-425	187	33	2013	2013	NUM
admet-425	187	34	)	)	PUNCT
admet-425	187	35	10–21	10–21	NUM
admet-425	187	36	.	.	PUNCT
admet-425	188	1	[	[	X
admet-425	188	2	23	23	NUM
admet-425	188	3	]	]	X
admet-425	188	4	d.h	d.h	PROPN
admet-425	188	5	.	.	PROPN
admet-425	188	6	owen	owen	PROPN
admet-425	188	7	,	,	PUNCT
admet-425	188	8	d.f	d.f	PROPN
admet-425	188	9	.	.	PROPN
admet-425	188	10	katz	katz	PROPN
admet-425	188	11	,	,	PUNCT
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admet-425	188	13	59	59	NUM
admet-425	188	14	(	(	PUNCT
admet-425	188	15	1999	1999	NUM
admet-425	188	16	)	)	PUNCT
admet-425	188	17	91–95	91–95	NUM
admet-425	188	18	.	.	PUNCT
admet-425	189	1	[	[	X
admet-425	189	2	24	24	NUM
admet-425	189	3	]	]	X
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admet-425	189	6	,	,	PUNCT
admet-425	189	7	g.	g.	PROPN
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admet-425	189	9	,	,	PUNCT
admet-425	189	10	l.	l.	PROPN
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admet-425	189	12	,	,	PUNCT
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admet-425	189	15	,	,	PUNCT
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admet-425	189	19	,	,	PUNCT
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admet-425	189	21	brunetti	brunetti	PROPN
admet-425	189	22	,	,	PUNCT
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admet-425	189	26	a.	a.	NOUN
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admet-425	189	28	,	,	PUNCT
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admet-425	189	32	sciences	science	NOUN
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admet-425	189	34	(	(	PUNCT
admet-425	189	35	2011	2011	NUM
admet-425	189	36	)	)	PUNCT
admet-425	189	37	1488–1502	1488–1502	NUM
admet-425	189	38	.	.	PUNCT
admet-425	190	1	[	[	X
admet-425	190	2	25	25	NUM
admet-425	190	3	]	]	X
admet-425	190	4	a.g	a.g	PROPN
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admet-425	190	16	:	:	PUNCT
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admet-425	190	19	(	(	PUNCT
admet-425	190	20	2016	2016	NUM
admet-425	190	21	)	)	PUNCT
admet-425	190	22	329–335	329–335	NUM
admet-425	190	23	.	.	PUNCT
admet-425	191	1	[	[	X
admet-425	191	2	26	26	NUM
admet-425	191	3	]	]	X
admet-425	191	4	g.m	g.m	PROPN
admet-425	191	5	.	.	PUNCT
admet-425	192	1	el	el	PROPN
admet-425	192	2	-	-	PUNCT
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admet-425	192	4	,	,	PUNCT
admet-425	192	5	o.n	o.n	PROPN
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admet-425	192	8	-	-	PUNCT
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admet-425	192	14	,	,	PUNCT
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admet-425	192	20	journal	journal	NOUN
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admet-425	192	24	(	(	PUNCT
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admet-425	192	26	)	)	PUNCT
admet-425	193	1	100–112	100–112	NUM
admet-425	193	2	.	.	PUNCT
admet-425	194	1	[	[	X
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admet-425	194	3	]	]	X
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admet-425	194	5	.	.	PUNCT
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admet-425	195	10	,	,	PUNCT
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admet-425	195	16	(	(	PUNCT
admet-425	195	17	2014	2014	NUM
admet-425	195	18	)	)	PUNCT
admet-425	195	19	68	68	NUM
admet-425	195	20	–	–	PUNCT
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admet-425	195	22	.	.	PUNCT
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admet-425	196	39	2011	2011	NUM
admet-425	196	40	)	)	PUNCT
admet-425	196	41	1–7	1–7	X
admet-425	196	42	.	.	PUNCT
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admet-425	197	3	]	]	X
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admet-425	197	17	j.h	j.h	PROPN
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admet-425	197	44	pharmaceutics	pharmaceutic	NOUN
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admet-425	197	50	)	)	PUNCT
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admet-425	197	52	.	.	PUNCT
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admet-425	198	3	]	]	X
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admet-425	198	15	e.b	e.b	PROPN
admet-425	198	16	.	.	PROPN
admet-425	198	17	jørgensen	jørgensen	PROPN
admet-425	198	18	,	,	PUNCT
admet-425	198	19	r.	r.	PROPN
admet-425	198	20	holm	holm	PROPN
admet-425	198	21	,	,	PUNCT
admet-425	198	22	international	international	ADJ
admet-425	198	23	journal	journal	NOUN
admet-425	198	24	of	of	ADP
admet-425	198	25	pharmaceutics	pharmaceutic	NOUN
admet-425	198	26	515	515	NUM
admet-425	198	27	(	(	PUNCT
admet-425	198	28	2016	2016	NUM
admet-425	198	29	)	)	PUNCT
admet-425	198	30	125–131	125–131	NUM
admet-425	198	31	.	.	PUNCT
admet-425	199	1	[	[	X
admet-425	199	2	31	31	NUM
admet-425	199	3	]	]	X
admet-425	199	4	s.a	s.a	PROPN
admet-425	199	5	.	.	PROPN
admet-425	199	6	fouad	fouad	PROPN
admet-425	199	7	,	,	PUNCT
admet-425	199	8	r.n	r.n	PROPN
admet-425	199	9	.	.	PROPN
admet-425	199	10	shamma	shamma	PROPN
admet-425	199	11	,	,	PUNCT
admet-425	199	12	e.b	e.b	PROPN
admet-425	199	13	.	.	PROPN
admet-425	199	14	basalious	basalious	PROPN
admet-425	199	15	,	,	PUNCT
admet-425	199	16	m.a	m.a	PROPN
admet-425	199	17	.	.	PROPN
admet-425	199	18	el	el	PROPN
admet-425	199	19	-	-	PUNCT
admet-425	199	20	nabarawi	nabarawi	PROPN
admet-425	199	21	,	,	PUNCT
admet-425	199	22	s.a	s.a	PROPN
admet-425	199	23	.	.	PROPN
admet-425	199	24	tayel	tayel	PROPN
admet-425	199	25	,	,	PUNCT
admet-425	199	26	international	international	ADJ
admet-425	199	27	journal	journal	NOUN
admet-425	199	28	of	of	ADP
admet-425	199	29	pharmaceutics	pharmaceutic	NOUN
admet-425	199	30	505	505	NUM
admet-425	199	31	(	(	PUNCT
admet-425	199	32	2016	2016	NUM
admet-425	199	33	)	)	PUNCT
admet-425	199	34	212–222	212–222	NUM
admet-425	199	35	.	.	PUNCT
admet-425	200	1	[	[	X
admet-425	200	2	32	32	NUM
admet-425	200	3	]	]	PUNCT
admet-425	200	4	l.	l.	PROPN
admet-425	200	5	wang	wang	PROPN
admet-425	200	6	,	,	PUNCT
admet-425	200	7	x.	x.	PROPN
admet-425	200	8	tang	tang	PROPN
admet-425	200	9	,	,	PUNCT
admet-425	200	10	international	international	ADJ
admet-425	200	11	journal	journal	NOUN
admet-425	200	12	of	of	ADP
admet-425	200	13	pharmaceutics	pharmaceutic	NOUN
admet-425	200	14	350	350	NUM
admet-425	200	15	(	(	PUNCT
admet-425	200	16	2008	2008	NUM
admet-425	200	17	)	)	PUNCT
admet-425	200	18	181–187	181–187	NUM
admet-425	200	19	.	.	PUNCT
admet-425	201	1	[	[	X
admet-425	201	2	33	33	NUM
admet-425	201	3	]	]	X
admet-425	201	4	d.	d.	PROPN
admet-425	201	5	gugulothu	gugulothu	PROPN
admet-425	201	6	,	,	PUNCT
admet-425	201	7	s.	s.	PROPN
admet-425	201	8	pathak	pathak	PROPN
admet-425	201	9	,	,	PUNCT
admet-425	201	10	s.	s.	PROPN
admet-425	201	11	suryavanshi	suryavanshi	PROPN
admet-425	201	12	,	,	PUNCT
admet-425	201	13	s.	s.	PROPN
admet-425	201	14	sharma	sharma	PROPN
admet-425	201	15	,	,	PUNCT
admet-425	201	16	v.	v.	PROPN
admet-425	201	17	patravale	patravale	PROPN
admet-425	201	18	,	,	PUNCT
admet-425	201	19	aaps	aap	NOUN
admet-425	201	20	pharmscitech	pharmscitech	VERB
admet-425	201	21	11	11	NUM
admet-425	201	22	(	(	PUNCT
admet-425	201	23	2010	2010	NUM
admet-425	201	24	)	)	PUNCT
admet-425	201	25	1179–1184	1179–1184	NUM
admet-425	201	26	.	.	PUNCT
admet-425	202	1	[	[	X
admet-425	202	2	34	34	NUM
admet-425	202	3	]	]	X
admet-425	202	4	o.a	o.a	PROPN
admet-425	202	5	.	.	PROPN
admet-425	202	6	adeleke	adeleke	PROPN
admet-425	202	7	,	,	PUNCT
admet-425	202	8	y.e	y.e	PROPN
admet-425	202	9	.	.	PROPN
admet-425	202	10	choonara	choonara	PROPN
admet-425	202	11	,	,	PUNCT
admet-425	202	12	l.c	l.c	PROPN
admet-425	202	13	.	.	PROPN
admet-425	202	14	du	du	PROPN
admet-425	202	15	toit	toit	PROPN
admet-425	202	16	,	,	PUNCT
admet-425	202	17	v.	v.	PROPN
admet-425	202	18	pillay	pillay	PROPN
admet-425	202	19	,	,	PUNCT
admet-425	202	20	journal	journal	NOUN
admet-425	202	21	of	of	ADP
admet-425	202	22	pharmaceutical	pharmaceutical	PROPN
admet-425	202	23	sciences	science	NOUN
admet-425	202	24	103	103	NUM
admet-425	202	25	(	(	PUNCT
admet-425	202	26	2014	2014	NUM
admet-425	202	27	)	)	PUNCT
admet-425	202	28	1157–1169	1157–1169	NUM
admet-425	202	29	.	.	PUNCT
admet-425	203	1	[	[	X
admet-425	203	2	35	35	NUM
admet-425	203	3	]	]	PUNCT
admet-425	203	4	m.	m.	NOUN
admet-425	203	5	jug	jug	PROPN
admet-425	203	6	,	,	PUNCT
admet-425	203	7	i.	i.	PROPN
admet-425	203	8	kosalec	kosalec	PROPN
admet-425	203	9	,	,	PUNCT
admet-425	203	10	f.	f.	PROPN
admet-425	203	11	maestrelli	maestrelli	PROPN
admet-425	203	12	,	,	PUNCT
admet-425	203	13	p.	p.	PROPN
admet-425	203	14	mura	mura	PROPN
admet-425	203	15	,	,	PUNCT
admet-425	203	16	carbohydrate	carbohydrate	VERB
admet-425	203	17	polymers	polymer	NOUN
admet-425	203	18	90	90	NUM
admet-425	203	19	(	(	PUNCT
admet-425	203	20	2012	2012	NUM
admet-425	203	21	)	)	PUNCT
admet-425	203	22	1794–1803	1794–1803	NUM
admet-425	203	23	.	.	PUNCT
admet-425	204	1	[	[	X
admet-425	204	2	36	36	NUM
admet-425	204	3	]	]	X
admet-425	204	4	p.j	p.j	PROPN
admet-425	204	5	.	.	PROPN
admet-425	204	6	marroum	marroum	PROPN
admet-425	204	7	,	,	PUNCT
admet-425	204	8	in	in	ADP
admet-425	204	9	:	:	PUNCT
admet-425	204	10	pharmaceutical	pharmaceutical	ADJ
admet-425	204	11	product	product	NOUN
admet-425	204	12	development	development	NOUN
admet-425	204	13	:	:	PUNCT
admet-425	204	14	in	in	ADP
admet-425	204	15	vitro	vitro	VERB
admet-425	204	16	-	-	PUNCT
admet-425	204	17	in	in	ADP
admet-425	204	18	vivo	vivo	NOUN
admet-425	204	19	correlation	correlation	NOUN
admet-425	204	20	,	,	PUNCT
admet-425	204	21	d.	d.	PROPN
admet-425	204	22	murthy	murthy	PROPN
admet-425	204	23	chilukuri	chilukuri	PROPN
admet-425	204	24	,	,	PUNCT
admet-425	204	25	g.	g.	PROPN
admet-425	204	26	sunkara	sunkara	PROPN
admet-425	204	27	,	,	PUNCT
admet-425	204	28	d.	d.	PROPN
admet-425	204	29	young	young	PROPN
admet-425	204	30	(	(	PUNCT
admet-425	204	31	eds	ed	NOUN
admet-425	204	32	.	.	PUNCT
admet-425	204	33	)	)	PUNCT
admet-425	204	34	,	,	PUNCT
admet-425	204	35	informa	informa	PROPN
admet-425	204	36	healthcare	healthcare	PROPN
admet-425	204	37	usa	usa	PROPN
admet-425	204	38	,	,	PUNCT
admet-425	204	39	inc	inc	PROPN
admet-425	204	40	,	,	PUNCT
admet-425	204	41	new	new	PROPN
admet-425	204	42	york	york	PROPN
admet-425	204	43	,	,	PUNCT
admet-425	204	44	london	london	PROPN
admet-425	204	45	,	,	PUNCT
admet-425	204	46	2007	2007	NUM
admet-425	204	47	,	,	PUNCT
admet-425	204	48	pp	pp	ADJ
admet-425	204	49	.	.	PUNCT
admet-425	205	1	177–195	177–195	NUM
admet-425	205	2	.	.	PUNCT
admet-425	206	1	[	[	X
admet-425	206	2	37	37	NUM
admet-425	206	3	]	]	X
admet-425	206	4	l.	l.	PROPN
admet-425	206	5	perioli	perioli	PROPN
admet-425	206	6	,	,	PUNCT
admet-425	206	7	c.	c.	PROPN
admet-425	206	8	pagano	pagano	PROPN
admet-425	206	9	,	,	PUNCT
admet-425	206	10	colloids	colloids	PROPN
admet-425	206	11	surfaces	surface	NOUN
admet-425	206	12	b	b	PROPN
admet-425	206	13	biointerfaces	biointerface	NOUN
admet-425	206	14	102	102	NUM
admet-425	206	15	(	(	PUNCT
admet-425	206	16	2013	2013	NUM
admet-425	206	17	)	)	PUNCT
admet-425	206	18	915–922	915–922	NUM
admet-425	206	19	.	.	PUNCT
admet-425	207	1	[	[	X
admet-425	207	2	38	38	NUM
admet-425	207	3	]	]	PUNCT
admet-425	207	4	j.	j.	PROPN
admet-425	207	5	xu	xu	PROPN
admet-425	207	6	,	,	PUNCT
admet-425	207	7	s.	s.	PROPN
admet-425	207	8	strandman	strandman	PROPN
admet-425	207	9	,	,	PUNCT
admet-425	207	10	j.x.x	j.x.x	NOUN
admet-425	207	11	.	.	PUNCT
admet-425	208	1	zhu	zhu	PROPN
admet-425	208	2	,	,	PUNCT
admet-425	208	3	j.	j.	PROPN
admet-425	208	4	barralet	barralet	PROPN
admet-425	208	5	,	,	PUNCT
admet-425	208	6	m.	m.	NOUN
admet-425	208	7	cerruti	cerruti	NOUN
admet-425	208	8	,	,	PUNCT
admet-425	208	9	biomaterials	biomaterial	VERB
admet-425	208	10	37	37	NUM
admet-425	208	11	(	(	PUNCT
admet-425	208	12	2015	2015	NUM
admet-425	208	13	)	)	PUNCT
admet-425	208	14	395–404	395–404	NUM
admet-425	208	15	.	.	PUNCT
admet-425	209	1	[	[	X
admet-425	209	2	39	39	NUM
admet-425	209	3	]	]	PUNCT
admet-425	209	4	d’souza	d’souza	PROPN
admet-425	209	5	suzan	suzan	PROPN
admet-425	209	6	,	,	PUNCT
admet-425	209	7	advances	advance	NOUN
admet-425	209	8	in	in	ADP
admet-425	209	9	pharmaceutics	pharmaceutic	NOUN
admet-425	209	10	2014	2014	NUM
admet-425	209	11	(	(	PUNCT
admet-425	209	12	2014	2014	NUM
admet-425	209	13	)	)	PUNCT
admet-425	209	14	1–12	1–12	NOUN
admet-425	209	15	.	.	PUNCT
admet-425	210	1	[	[	X
admet-425	210	2	40	40	NUM
admet-425	210	3	]	]	PUNCT
admet-425	210	4	s.	s.	PROPN
admet-425	210	5	modi	modi	PROPN
admet-425	210	6	,	,	PUNCT
admet-425	210	7	b.d	b.d	PROPN
admet-425	210	8	.	.	PROPN
admet-425	210	9	anderson	anderson	PROPN
admet-425	210	10	,	,	PUNCT
admet-425	210	11	molecular	molecular	ADJ
admet-425	210	12	pharmaceutics	pharmaceutic	NOUN
admet-425	210	13	10	10	NUM
admet-425	210	14	(	(	PUNCT
admet-425	210	15	2013	2013	NUM
admet-425	210	16	)	)	PUNCT
admet-425	210	17	3076–3089	3076–3089	NOUN
admet-425	210	18	.	.	PUNCT
admet-425	211	1	[	[	X
admet-425	211	2	41	41	NUM
admet-425	211	3	]	]	X
admet-425	211	4	y.	y.	PROPN
admet-425	211	5	zambito	zambito	PROPN
admet-425	211	6	,	,	PUNCT
admet-425	211	7	e.	e.	PROPN
admet-425	211	8	pedreschi	pedreschi	PROPN
admet-425	211	9	,	,	PUNCT
admet-425	211	10	g.	g.	PROPN
admet-425	211	11	di	di	PROPN
admet-425	211	12	colo	colo	PROPN
admet-425	211	13	,	,	PUNCT
admet-425	211	14	international	international	ADJ
admet-425	211	15	journal	journal	NOUN
admet-425	211	16	of	of	ADP
admet-425	211	17	pharmaceutics	pharmaceutic	NOUN
admet-425	211	18	434	434	NUM
admet-425	211	19	(	(	PUNCT
admet-425	211	20	2012	2012	NUM
admet-425	211	21	)	)	PUNCT
admet-425	211	22	28–34	28–34	NUM
admet-425	211	23	.	.	PUNCT
admet-425	212	1	[	[	X
admet-425	212	2	42	42	NUM
admet-425	212	3	]	]	X
admet-425	212	4	h.	h.	PROPN
admet-425	212	5	onishi	onishi	PROPN
admet-425	212	6	,	,	PUNCT
admet-425	212	7	k.	k.	PROPN
admet-425	212	8	yumoto	yumoto	NOUN
admet-425	212	9	,	,	PUNCT
admet-425	212	10	o.	o.	NOUN
admet-425	212	11	sakata	sakata	NOUN
admet-425	212	12	,	,	PUNCT
admet-425	212	13	international	international	ADJ
admet-425	212	14	journal	journal	NOUN
admet-425	212	15	of	of	ADP
admet-425	212	16	pharmaceutics	pharmaceutic	NOUN
admet-425	212	17	468	468	NUM
admet-425	212	18	(	(	PUNCT
admet-425	212	19	2014	2014	NUM
admet-425	212	20	)	)	PUNCT
admet-425	212	21	207–213	207–213	NUM
admet-425	212	22	.	.	PUNCT
admet-425	213	1	[	[	X
admet-425	213	2	43	43	NUM
admet-425	213	3	]	]	X
admet-425	213	4	r.	r.	PROPN
admet-425	213	5	kumria	kumria	PROPN
admet-425	213	6	,	,	PUNCT
admet-425	213	7	a.b	a.b	PROPN
admet-425	213	8	.	.	PROPN
admet-425	213	9	nair	nair	PROPN
admet-425	213	10	,	,	PUNCT
admet-425	213	11	b.e	b.e	PROPN
admet-425	213	12	.	.	PROPN
admet-425	213	13	al	al	PROPN
admet-425	213	14	-	-	PUNCT
admet-425	213	15	dhubiab	dhubiab	PROPN
admet-425	213	16	,	,	PUNCT
admet-425	213	17	drug	drug	NOUN
admet-425	213	18	development	development	NOUN
admet-425	213	19	and	and	CCONJ
admet-425	213	20	industrial	industrial	ADJ
admet-425	213	21	pharmacy	pharmacy	NOUN
admet-425	213	22	40	40	NUM
admet-425	213	23	(	(	PUNCT
admet-425	213	24	2014	2014	NUM
admet-425	213	25	)	)	PUNCT
admet-425	213	26	625	625	NUM
admet-425	213	27	–	–	PUNCT
admet-425	213	28	631	631	NUM
admet-425	213	29	.	.	PUNCT
admet-425	214	1	[	[	X
admet-425	214	2	44	44	NUM
admet-425	214	3	]	]	X
admet-425	214	4	y.	y.	PROPN
admet-425	214	5	yuan	yuan	PROPN
admet-425	214	6	,	,	PUNCT
admet-425	214	7	y.	y.	PROPN
admet-425	214	8	cui	cui	PROPN
admet-425	214	9	,	,	PUNCT
admet-425	214	10	l.	l.	PROPN
admet-425	214	11	zhang	zhang	PROPN
admet-425	214	12	,	,	PUNCT
admet-425	214	13	h.p	h.p	PROPN
admet-425	214	14	.	.	PROPN
admet-425	214	15	zhu	zhu	PROPN
admet-425	214	16	,	,	PUNCT
admet-425	214	17	y.s	y.s	PROPN
admet-425	214	18	.	.	PROPN
admet-425	214	19	guo	guo	PROPN
admet-425	214	20	,	,	PUNCT
admet-425	214	21	b.	b.	PROPN
admet-425	214	22	zhong	zhong	PROPN
admet-425	214	23	,	,	PUNCT
admet-425	214	24	x.	x.	PROPN
admet-425	214	25	hu	hu	PROPN
admet-425	214	26	,	,	PUNCT
admet-425	214	27	l.	l.	PROPN
admet-425	214	28	zhang	zhang	PROPN
admet-425	214	29	,	,	PUNCT
admet-425	214	30	x.h	x.h	PROPN
admet-425	214	31	.	.	PROPN
admet-425	214	32	wang	wang	PROPN
admet-425	214	33	,	,	PUNCT
admet-425	214	34	l.	l.	PROPN
admet-425	214	35	chen	chen	PROPN
admet-425	214	36	,	,	PUNCT
admet-425	214	37	international	international	ADJ
admet-425	214	38	journal	journal	NOUN
admet-425	214	39	of	of	ADP
admet-425	214	40	pharmaceutics	pharmaceutic	NOUN
admet-425	214	41	430	430	NUM
admet-425	214	42	(	(	PUNCT
admet-425	214	43	2012	2012	NUM
admet-425	214	44	)	)	PUNCT
admet-425	214	45	114–119	114–119	NUM
admet-425	214	46	.	.	PUNCT
admet-425	215	1	[	[	X
admet-425	215	2	45	45	NUM
admet-425	215	3	]	]	X
admet-425	215	4	r.	r.	PROPN
admet-425	215	5	kamel	kamel	PROPN
admet-425	215	6	,	,	PUNCT
admet-425	215	7	m.	m.	PROPN
admet-425	215	8	basha	basha	PROPN
admet-425	215	9	,	,	PUNCT
admet-425	215	10	s.h	s.h	PROPN
admet-425	215	11	.	.	PROPN
admet-425	215	12	abd	abd	PROPN
admet-425	215	13	el	el	PROPN
admet-425	215	14	-	-	PUNCT
admet-425	215	15	alim	alim	ADJ
admet-425	215	16	,	,	PUNCT
admet-425	215	17	journal	journal	NOUN
admet-425	215	18	of	of	ADP
admet-425	215	19	liposome	liposome	NOUN
admet-425	215	20	research	research	NOUN
admet-425	215	21	23	23	NUM
admet-425	215	22	(	(	PUNCT
admet-425	215	23	2013	2013	NUM
admet-425	215	24	)	)	PUNCT
admet-425	215	25	28–36	28–36	NUM
admet-425	215	26	.	.	PUNCT
admet-425	216	1	[	[	X
admet-425	216	2	46	46	NUM
admet-425	216	3	]	]	SYM
admet-425	216	4	a.e.s.f	a.e.s.f	PROPN
admet-425	216	5	.	.	PROPN
admet-425	216	6	abou	abou	PROPN
admet-425	216	7	el	el	PROPN
admet-425	216	8	ela	ela	PROPN
admet-425	216	9	,	,	PUNCT
admet-425	216	10	a.	a.	PROPN
admet-425	216	11	a.	a.	PROPN
admet-425	216	12	allam	allam	PROPN
admet-425	216	13	,	,	PUNCT
admet-425	216	14	e.h	e.h	PROPN
admet-425	216	15	.	.	PROPN
admet-425	216	16	ibrahim	ibrahim	PROPN
admet-425	216	17	,	,	PUNCT
admet-425	216	18	drug	drug	NOUN
admet-425	216	19	delivery	delivery	NOUN
admet-425	216	20	7544	7544	NUM
admet-425	216	21	(	(	PUNCT
admet-425	216	22	2014	2014	NUM
admet-425	216	23	)	)	PUNCT
admet-425	216	24	1–10	1–10	NOUN
admet-425	216	25	.	.	PUNCT
admet-425	217	1	[	[	X
admet-425	217	2	47	47	NUM
admet-425	217	3	]	]	X
admet-425	217	4	a.p	a.p	PROPN
admet-425	217	5	.	.	PROPN
admet-425	217	6	gorle	gorle	PROPN
admet-425	217	7	,	,	PUNCT
admet-425	217	8	s.g	s.g	PROPN
admet-425	217	9	.	.	PROPN
admet-425	217	10	gattani	gattani	PROPN
admet-425	217	11	,	,	PUNCT
admet-425	217	12	chemical	chemical	NOUN
admet-425	217	13	and	and	CCONJ
admet-425	217	14	pharmaceutical	pharmaceutical	NOUN
admet-425	217	15	bulletin	bulletin	NOUN
admet-425	217	16	57	57	NUM
admet-425	217	17	(	(	PUNCT
admet-425	217	18	2009	2009	NUM
admet-425	217	19	)	)	PUNCT
admet-425	217	20	914–919	914–919	NUM
admet-425	217	21	.	.	PUNCT
admet-425	218	1	[	[	X
admet-425	218	2	48	48	NUM
admet-425	218	3	]	]	X
admet-425	218	4	d.	d.	PROPN
admet-425	218	5	chicco	chicco	PROPN
admet-425	218	6	,	,	PUNCT
admet-425	218	7	i.	i.	PROPN
admet-425	218	8	grabnar	grabnar	PROPN
admet-425	218	9	,	,	PUNCT
admet-425	218	10	a.	a.	NOUN
admet-425	218	11	škerjanec	škerjanec	PROPN
admet-425	218	12	,	,	PUNCT
admet-425	218	13	d.	d.	PROPN
admet-425	218	14	vojnović	vojnović	PROPN
admet-425	218	15	,	,	PUNCT
admet-425	218	16	v.	v.	ADP
admet-425	218	17	maurich	maurich	NOUN
admet-425	218	18	,	,	PUNCT
admet-425	218	19	n.	n.	PROPN
admet-425	218	20	realdon	realdon	PROPN
admet-425	218	21	,	,	PUNCT
admet-425	218	22	e.	e.	PROPN
admet-425	218	23	ragazzi	ragazzi	PROPN
admet-425	218	24	,	,	PUNCT
admet-425	218	25	a.	a.	PROPN
admet-425	218	26	belič	belič	PROPN
admet-425	218	27	,	,	PUNCT
admet-425	218	28	r.	r.	PROPN
admet-425	218	29	karba	karba	PROPN
admet-425	218	30	,	,	PUNCT
admet-425	218	31	a.	a.	PROPN
admet-425	218	32	mrhar	mrhar	PROPN
admet-425	218	33	,	,	PUNCT
admet-425	218	34	international	international	ADJ
admet-425	218	35	journal	journal	NOUN
admet-425	218	36	of	of	ADP
admet-425	218	37	pharmaceutics	pharmaceutic	NOUN
admet-425	218	38	189	189	NUM
admet-425	218	39	(	(	PUNCT
admet-425	218	40	1999	1999	NUM
admet-425	218	41	)	)	PUNCT
admet-425	218	42	147–160	147–160	NUM
admet-425	218	43	.	.	PUNCT
admet-425	219	1	[	[	X
admet-425	219	2	49	49	NUM
admet-425	219	3	]	]	X
admet-425	219	4	a.s	a.s	PROPN
admet-425	219	5	.	.	PROPN
admet-425	219	6	zidan	zidan	PROPN
admet-425	219	7	,	,	PUNCT
admet-425	219	8	s.e	s.e	PROPN
admet-425	219	9	.	.	PROPN
admet-425	219	10	emam	emam	PROPN
admet-425	219	11	,	,	PUNCT
admet-425	219	12	t.m	t.m	PROPN
admet-425	219	13	.	.	PROPN
admet-425	219	14	shehata	shehata	PROPN
admet-425	219	15	,	,	PUNCT
admet-425	219	16	f.s	f.s	PROPN
admet-425	219	17	.	.	PROPN
admet-425	219	18	ghazy	ghazy	PROPN
admet-425	219	19	,	,	PUNCT
admet-425	219	20	aaps	aap	NOUN
admet-425	219	21	pharmscitech	pharmscitech	VERB
admet-425	219	22	16	16	NUM
admet-425	219	23	(	(	PUNCT
admet-425	219	24	2015	2015	NUM
admet-425	219	25	)	)	PUNCT
admet-425	220	1	645–655	645–655	NUM
admet-425	220	2	.	.	PUNCT
admet-425	221	1	[	[	X
admet-425	221	2	50	50	NUM
admet-425	221	3	]	]	X
admet-425	221	4	y.	y.	PROPN
admet-425	221	5	sultana	sultana	PROPN
admet-425	221	6	,	,	PUNCT
admet-425	221	7	m.	m.	PROPN
admet-425	221	8	aqil	aqil	PROPN
admet-425	221	9	,	,	PUNCT
admet-425	221	10	a.	a.	PROPN
admet-425	221	11	ali	ali	PROPN
admet-425	221	12	,	,	PUNCT
admet-425	221	13	acta	acta	PROPN
admet-425	221	14	pharmaceutica	pharmaceutica	PROPN
admet-425	221	15	55	55	NUM
admet-425	221	16	(	(	PUNCT
admet-425	221	17	2005	2005	NUM
admet-425	221	18	)	)	PUNCT
admet-425	221	19	305–314	305–314	NUM
admet-425	221	20	.	.	PUNCT
admet-425	222	1	[	[	X
admet-425	222	2	51	51	NUM
admet-425	222	3	]	]	PUNCT
admet-425	222	4	a.	a.	NOUN
admet-425	222	5	mahomed	mahomed	PROPN
admet-425	222	6	,	,	PUNCT
admet-425	222	7	j.s	j.s	PROPN
admet-425	222	8	.	.	PROPN
admet-425	222	9	wolffsohn	wolffsohn	PROPN
admet-425	222	10	,	,	PUNCT
admet-425	222	11	b.j	b.j	PROPN
admet-425	222	12	.	.	PROPN
admet-425	222	13	tighe	tighe	PROPN
admet-425	222	14	,	,	PUNCT
admet-425	222	15	contact	contact	NOUN
admet-425	222	16	lens	len	NOUN
admet-425	222	17	anterior	anterior	VERB
admet-425	222	18	eye	eye	NOUN
admet-425	222	19	39	39	NUM
admet-425	222	20	(	(	PUNCT
admet-425	222	21	2016	2016	NUM
admet-425	222	22	)	)	PUNCT
admet-425	223	1	97–105	97–105	PROPN
admet-425	223	2	.	.	PUNCT
admet-425	224	1	mario	mario	PROPN
admet-425	224	2	jug	jug	PROPN
admet-425	224	3	et	et	PROPN
admet-425	224	4	al	al	PROPN
admet-425	224	5	.	.	PROPN
admet-425	224	6	admet	admet	PROPN
admet-425	224	7	&	&	CCONJ
admet-425	224	8	dmpk	dmpk	PROPN
admet-425	224	9	5(3	5(3	NUM
admet-425	224	10	)	)	PUNCT
admet-425	224	11	(	(	PUNCT
admet-425	224	12	2017	2017	NUM
admet-425	224	13	)	)	PUNCT
admet-425	224	14	173	173	NUM
admet-425	224	15	-	-	SYM
admet-425	224	16	182	182	NUM
admet-425	224	17	182	182	NUM
admet-425	224	18	[	[	X
admet-425	224	19	52	52	NUM
admet-425	224	20	]	]	PUNCT
admet-425	224	21	a.	a.	NOUN
admet-425	224	22	dalpiaz	dalpiaz	PROPN
admet-425	224	23	,	,	PUNCT
admet-425	224	24	m.	m.	NOUN
admet-425	224	25	fogagnolo	fogagnolo	PROPN
admet-425	224	26	,	,	PUNCT
admet-425	224	27	l.	l.	PROPN
admet-425	224	28	ferraro	ferraro	PROPN
admet-425	224	29	,	,	PUNCT
admet-425	224	30	a.	a.	NOUN
admet-425	224	31	capuzzo	capuzzo	PROPN
admet-425	224	32	,	,	PUNCT
admet-425	224	33	b.	b.	PROPN
admet-425	224	34	pavan	pavan	PROPN
admet-425	224	35	,	,	PUNCT
admet-425	224	36	g.	g.	PROPN
admet-425	224	37	rassu	rassu	PROPN
admet-425	224	38	,	,	PUNCT
admet-425	224	39	a.	a.	NOUN
admet-425	224	40	salis	salis	PROPN
admet-425	224	41	,	,	PUNCT
admet-425	224	42	p.	p.	PROPN
admet-425	224	43	giunchedi	giunchedi	PROPN
admet-425	224	44	,	,	PUNCT
admet-425	224	45	e.	e.	PROPN
admet-425	224	46	gavini	gavini	PROPN
admet-425	224	47	,	,	PUNCT
admet-425	224	48	antiviral	antiviral	ADJ
admet-425	224	49	research	research	NOUN
admet-425	224	50	123	123	NUM
admet-425	224	51	(	(	PUNCT
admet-425	224	52	2015	2015	NUM
admet-425	224	53	)	)	PUNCT
admet-425	224	54	146–157	146–157	NUM
admet-425	224	55	.	.	PUNCT
admet-425	225	1	[	[	X
admet-425	225	2	53	53	NUM
admet-425	225	3	]	]	X
admet-425	225	4	n.	n.	PROPN
admet-425	225	5	zeng	zeng	PROPN
admet-425	225	6	,	,	PUNCT
admet-425	225	7	g.	g.	PROPN
admet-425	225	8	dumortier	dumortier	PROPN
admet-425	225	9	,	,	PUNCT
admet-425	225	10	m.	m.	NOUN
admet-425	225	11	maury	maury	PROPN
admet-425	225	12	,	,	PUNCT
admet-425	225	13	n.	n.	NOUN
admet-425	225	14	mignet	mignet	PROPN
admet-425	225	15	,	,	PUNCT
admet-425	225	16	v.	v.	ADP
admet-425	225	17	boudy	boudy	PROPN
admet-425	225	18	,	,	PUNCT
admet-425	225	19	international	international	ADJ
admet-425	225	20	journal	journal	NOUN
admet-425	225	21	of	of	ADP
admet-425	225	22	pharmaceutics	pharmaceutic	NOUN
admet-425	225	23	467	467	NUM
admet-425	225	24	(	(	PUNCT
admet-425	225	25	2014	2014	NUM
admet-425	225	26	)	)	PUNCT
admet-425	225	27	70–83	70–83	NOUN
admet-425	225	28	.	.	PUNCT
admet-425	226	1	[	[	X
admet-425	226	2	54	54	NUM
admet-425	226	3	]	]	X
admet-425	226	4	p.	p.	PROPN
admet-425	226	5	mura	mura	PROPN
admet-425	226	6	,	,	PUNCT
admet-425	226	7	n.	n.	PROPN
admet-425	226	8	mennini	mennini	PROPN
admet-425	226	9	,	,	PUNCT
admet-425	226	10	i.	i.	PROPN
admet-425	226	11	kosalec	kosalec	PROPN
admet-425	226	12	,	,	PUNCT
admet-425	226	13	s.	s.	PROPN
admet-425	226	14	furlanetto	furlanetto	PROPN
admet-425	226	15	,	,	PUNCT
admet-425	226	16	s.	s.	PROPN
admet-425	226	17	orlandini	orlandini	PROPN
admet-425	226	18	,	,	PUNCT
admet-425	226	19	m.	m.	NOUN
admet-425	226	20	jug	jug	NOUN
admet-425	226	21	,	,	PUNCT
admet-425	226	22	carbohydrate	carbohydrate	VERB
admet-425	226	23	polymers	polymer	NOUN
admet-425	226	24	121	121	NUM
admet-425	226	25	(	(	PUNCT
admet-425	226	26	2015	2015	NUM
admet-425	226	27	)	)	PUNCT
admet-425	226	28	231–240	231–240	NUM
admet-425	226	29	.	.	PUNCT
admet-425	227	1	[	[	X
admet-425	227	2	55	55	NUM
admet-425	227	3	]	]	PUNCT
admet-425	227	4	p.	p.	PROPN
admet-425	227	5	pandey	pandey	PROPN
admet-425	227	6	,	,	PUNCT
admet-425	227	7	p.j	p.j	PROPN
admet-425	227	8	.	.	PROPN
admet-425	227	9	cabot	cabot	PROPN
admet-425	227	10	,	,	PUNCT
admet-425	227	11	b.	b.	PROPN
admet-425	227	12	wallwork	wallwork	PROPN
admet-425	227	13	,	,	PUNCT
admet-425	227	14	b.j	b.j	PROPN
admet-425	227	15	.	.	PROPN
admet-425	227	16	panizza	panizza	PROPN
admet-425	227	17	,	,	PUNCT
admet-425	227	18	h.s	h.s	PROPN
admet-425	227	19	.	.	PROPN
admet-425	227	20	parekh	parekh	PROPN
admet-425	227	21	,	,	PUNCT
admet-425	227	22	european	european	PROPN
admet-425	227	23	journal	journal	PROPN
admet-425	227	24	of	of	ADP
admet-425	227	25	pharmaceutical	pharmaceutical	PROPN
admet-425	227	26	sciences	science	NOUN
admet-425	227	27	96	96	NUM
admet-425	227	28	(	(	PUNCT
admet-425	227	29	2017	2017	NUM
admet-425	227	30	)	)	PUNCT
admet-425	227	31	499–507	499–507	NUM
admet-425	227	32	.	.	PUNCT
admet-425	228	1	[	[	X
admet-425	228	2	56	56	NUM
admet-425	228	3	]	]	X
admet-425	228	4	s.r	s.r	PROPN
admet-425	228	5	.	.	PROPN
admet-425	228	6	salunke	salunke	PROPN
admet-425	228	7	,	,	PUNCT
admet-425	228	8	s.b	s.b	PROPN
admet-425	228	9	.	.	PROPN
admet-425	228	10	patil	patil	PROPN
admet-425	228	11	,	,	PUNCT
admet-425	228	12	international	international	ADJ
admet-425	228	13	journal	journal	NOUN
admet-425	228	14	of	of	ADP
admet-425	228	15	biological	biological	ADJ
admet-425	228	16	macromolecules	macromolecule	NOUN
admet-425	228	17	87	87	NUM
admet-425	228	18	(	(	PUNCT
admet-425	228	19	2016	2016	NUM
admet-425	228	20	)	)	PUNCT
admet-425	228	21	41–47	41–47	NOUN
admet-425	228	22	.	.	PUNCT
admet-425	229	1	[	[	X
admet-425	229	2	57	57	NUM
admet-425	229	3	]	]	X
admet-425	229	4	a.d	a.d	PROPN
admet-425	229	5	.	.	PROPN
admet-425	229	6	kulkarni	kulkarni	PROPN
admet-425	229	7	,	,	PUNCT
admet-425	229	8	d.b	d.b	PROPN
admet-425	229	9	.	.	PROPN
admet-425	229	10	bari	bari	PROPN
admet-425	229	11	,	,	PUNCT
admet-425	229	12	s.j	s.j	PROPN
admet-425	229	13	.	.	PROPN
admet-425	229	14	surana	surana	PROPN
admet-425	229	15	,	,	PUNCT
admet-425	229	16	c.	c.	PROPN
admet-425	229	17	v.	v.	PROPN
admet-425	229	18	pardeshi	pardeshi	PROPN
admet-425	229	19	,	,	PUNCT
admet-425	229	20	journal	journal	NOUN
admet-425	229	21	of	of	ADP
admet-425	229	22	drug	drug	NOUN
admet-425	229	23	delivery	delivery	NOUN
admet-425	229	24	science	science	NOUN
admet-425	229	25	and	and	CCONJ
admet-425	229	26	technology	technology	NOUN
admet-425	229	27	31	31	NUM
admet-425	229	28	(	(	PUNCT
admet-425	229	29	2016	2016	NUM
admet-425	229	30	)	)	PUNCT
admet-425	229	31	108–117	108–117	NUM
admet-425	229	32	.	.	PUNCT
admet-425	230	1	[	[	X
admet-425	230	2	58	58	NUM
admet-425	230	3	]	]	X
admet-425	230	4	t.b	t.b	PROPN
admet-425	230	5	.	.	PROPN
admet-425	230	6	devkar	devkar	PROPN
admet-425	230	7	,	,	PUNCT
admet-425	230	8	a.r	a.r	PROPN
admet-425	230	9	.	.	PROPN
admet-425	230	10	tekade	tekade	PROPN
admet-425	230	11	,	,	PUNCT
admet-425	230	12	k.r	k.r	PROPN
admet-425	230	13	.	.	PROPN
admet-425	230	14	khandelwal	khandelwal	PROPN
admet-425	230	15	,	,	PUNCT
admet-425	230	16	colloids	colloid	NOUN
admet-425	230	17	and	and	CCONJ
admet-425	230	18	surfaces	surface	NOUN
admet-425	230	19	b	b	NUM
admet-425	230	20	:	:	PUNCT
admet-425	230	21	biointerfaces	biointerface	NOUN
admet-425	230	22	122	122	NUM
admet-425	230	23	(	(	PUNCT
admet-425	230	24	2014	2014	NUM
admet-425	230	25	)	)	PUNCT
admet-425	230	26	143	143	NUM
admet-425	230	27	–	–	SYM
admet-425	230	28	150	150	NUM
admet-425	230	29	.	.	PUNCT
admet-425	231	1	[	[	X
admet-425	231	2	59	59	NUM
admet-425	231	3	]	]	PUNCT
admet-425	231	4	s.	s.	PROPN
admet-425	231	5	jose	jose	PROPN
admet-425	231	6	,	,	PUNCT
admet-425	231	7	c.r	c.r	PROPN
admet-425	231	8	.	.	PROPN
admet-425	231	9	ansa	ansa	PROPN
admet-425	231	10	,	,	PUNCT
admet-425	231	11	t.a	t.a	PROPN
admet-425	231	12	.	.	PROPN
admet-425	231	13	cinu	cinu	PROPN
admet-425	231	14	,	,	PUNCT
admet-425	231	15	a.j	a.j	PROPN
admet-425	231	16	.	.	PROPN
admet-425	231	17	chacko	chacko	PROPN
admet-425	231	18	,	,	PUNCT
admet-425	231	19	n.a	n.a	PROPN
admet-425	231	20	.	.	PROPN
admet-425	231	21	aleykutty	aleykutty	PROPN
admet-425	231	22	,	,	PUNCT
admet-425	231	23	s.	s.	PROPN
admet-425	231	24	v.	v.	PROPN
admet-425	231	25	ferreira	ferreira	PROPN
admet-425	231	26	,	,	PUNCT
admet-425	231	27	e.b	e.b	PROPN
admet-425	231	28	.	.	PROPN
admet-425	231	29	souto	souto	PROPN
admet-425	231	30	,	,	PUNCT
admet-425	231	31	international	international	ADJ
admet-425	231	32	journal	journal	NOUN
admet-425	231	33	of	of	ADP
admet-425	231	34	pharmaceutics	pharmaceutic	NOUN
admet-425	231	35	441	441	NUM
admet-425	231	36	(	(	PUNCT
admet-425	231	37	2013	2013	NUM
admet-425	231	38	)	)	PUNCT
admet-425	232	1	516–526	516–526	NUM
admet-425	232	2	.	.	PUNCT
admet-425	233	1	[	[	X
admet-425	233	2	60	60	NUM
admet-425	233	3	]	]	X
admet-425	233	4	g.m	g.m	PROPN
admet-425	233	5	.	.	PUNCT
admet-425	234	1	el	el	PROPN
admet-425	234	2	-	-	NOUN
admet-425	234	3	zaafarany	zaafarany	NOUN
admet-425	234	4	,	,	PUNCT
admet-425	234	5	m.e	m.e	PROPN
admet-425	234	6	.	.	PROPN
admet-425	234	7	soliman	soliman	PROPN
admet-425	234	8	,	,	PUNCT
admet-425	234	9	s.	s.	PROPN
admet-425	234	10	mansour	mansour	PROPN
admet-425	234	11	,	,	PUNCT
admet-425	234	12	g.a.s	g.a.s	PROPN
admet-425	234	13	.	.	PROPN
admet-425	234	14	awad	awad	PROPN
admet-425	234	15	,	,	PUNCT
admet-425	234	16	international	international	ADJ
admet-425	234	17	journal	journal	NOUN
admet-425	234	18	of	of	ADP
admet-425	234	19	pharmaceutics	pharmaceutic	NOUN
admet-425	234	20	503	503	NUM
admet-425	234	21	(	(	PUNCT
admet-425	234	22	2016	2016	NUM
admet-425	234	23	)	)	PUNCT
admet-425	234	24	127–140	127–140	NUM
admet-425	234	25	.	.	PUNCT
admet-425	235	1	[	[	X
admet-425	235	2	61	61	NUM
admet-425	235	3	]	]	PUNCT
admet-425	235	4	r.	r.	PROPN
admet-425	235	5	pathak	pathak	PROPN
admet-425	235	6	,	,	PUNCT
admet-425	235	7	r.	r.	PROPN
admet-425	235	8	prasad	prasad	PROPN
admet-425	235	9	dash	dash	NOUN
admet-425	235	10	,	,	PUNCT
admet-425	235	11	m.	m.	NOUN
admet-425	235	12	misra	misra	NOUN
admet-425	235	13	,	,	PUNCT
admet-425	235	14	m.	m.	NOUN
admet-425	235	15	nivsarkar	nivsarkar	NOUN
admet-425	235	16	,	,	PUNCT
admet-425	235	17	acta	acta	PROPN
admet-425	235	18	pharmaceutica	pharmaceutica	PROPN
admet-425	235	19	sinica	sinica	PROPN
admet-425	235	20	b	b	PROPN
admet-425	235	21	4	4	NUM
admet-425	235	22	(	(	PUNCT
admet-425	235	23	2014	2014	NUM
admet-425	235	24	)	)	PUNCT
admet-425	235	25	151–160	151–160	NUM
admet-425	235	26	.	.	PUNCT
admet-425	236	1	[	[	X
admet-425	236	2	62	62	NUM
admet-425	236	3	]	]	PUNCT
admet-425	236	4	b.	b.	PROPN
admet-425	236	5	shah	shah	PROPN
admet-425	236	6	,	,	PUNCT
admet-425	236	7	d.	d.	PROPN
admet-425	236	8	khunt	khunt	PROPN
admet-425	236	9	,	,	PUNCT
admet-425	236	10	h.	h.	PROPN
admet-425	236	11	bhatt	bhatt	PROPN
admet-425	236	12	,	,	PUNCT
admet-425	236	13	m.	m.	NOUN
admet-425	236	14	misra	misra	PROPN
admet-425	236	15	,	,	PUNCT
admet-425	236	16	h.	h.	PROPN
admet-425	236	17	padh	padh	PROPN
admet-425	236	18	,	,	PUNCT
admet-425	236	19	european	european	PROPN
admet-425	236	20	journal	journal	PROPN
admet-425	236	21	of	of	ADP
admet-425	236	22	pharmaceutical	pharmaceutical	PROPN
admet-425	236	23	sciences	science	NOUN
admet-425	236	24	78	78	NUM
admet-425	236	25	(	(	PUNCT
admet-425	236	26	2015	2015	NUM
admet-425	236	27	)	)	PUNCT
admet-425	236	28	54–66	54–66	NUM
admet-425	236	29	.	.	PUNCT
admet-425	237	1	[	[	X
admet-425	237	2	63	63	NUM
admet-425	237	3	]	]	PUNCT
admet-425	237	4	a.	a.	NOUN
admet-425	237	5	martinac	martinac	PROPN
admet-425	237	6	,	,	PUNCT
admet-425	237	7	j.	j.	PROPN
admet-425	237	8	filipović	filipović	PROPN
admet-425	237	9	-	-	PUNCT
admet-425	237	10	grčić	grčić	PROPN
admet-425	237	11	,	,	PUNCT
admet-425	237	12	b.	b.	PROPN
admet-425	237	13	perissutti	perissutti	PROPN
admet-425	237	14	,	,	PUNCT
admet-425	237	15	d.	d.	PROPN
admet-425	237	16	voinovich	voinovich	PROPN
admet-425	237	17	,	,	PUNCT
admet-425	237	18	ž	ž	PROPN
admet-425	237	19	.	.	NOUN
admet-425	237	20	pavelić	pavelić	NOUN
admet-425	237	21	,	,	PUNCT
admet-425	237	22	journal	journal	NOUN
admet-425	237	23	of	of	ADP
admet-425	237	24	microencapsulation	microencapsulation	NOUN
admet-425	237	25	22	22	NUM
admet-425	237	26	(	(	PUNCT
admet-425	237	27	2005	2005	NUM
admet-425	237	28	)	)	PUNCT
admet-425	237	29	549–561	549–561	NUM
admet-425	237	30	.	.	PUNCT
admet-425	238	1	[	[	X
admet-425	238	2	64	64	NUM
admet-425	238	3	]	]	X
admet-425	238	4	i.d	i.d	PROPN
admet-425	238	5	.	.	PROPN
admet-425	238	6	rupenthal	rupenthal	PROPN
admet-425	238	7	,	,	PUNCT
admet-425	238	8	c.r	c.r	PROPN
admet-425	238	9	.	.	PROPN
admet-425	238	10	green	green	PROPN
admet-425	238	11	,	,	PUNCT
admet-425	238	12	r.g	r.g	PROPN
admet-425	238	13	.	.	PROPN
admet-425	238	14	alany	alany	PROPN
admet-425	238	15	,	,	PUNCT
admet-425	238	16	international	international	ADJ
admet-425	238	17	journal	journal	NOUN
admet-425	238	18	of	of	ADP
admet-425	238	19	pharmaceutics	pharmaceutic	NOUN
admet-425	238	20	411	411	NUM
admet-425	238	21	(	(	PUNCT
admet-425	238	22	2011	2011	NUM
admet-425	238	23	)	)	PUNCT
admet-425	238	24	69–77	69–77	NUM
admet-425	238	25	.	.	PUNCT
admet-425	239	1	[	[	X
admet-425	239	2	65	65	NUM
admet-425	239	3	]	]	X
admet-425	239	4	a.	a.	NOUN
admet-425	239	5	mahor	mahor	NOUN
admet-425	239	6	,	,	PUNCT
admet-425	239	7	s.k	s.k	PROPN
admet-425	239	8	.	.	PROPN
admet-425	239	9	prajapati	prajapati	PROPN
admet-425	239	10	,	,	PUNCT
admet-425	239	11	a.	a.	PROPN
admet-425	239	12	verma	verma	PROPN
admet-425	239	13	,	,	PUNCT
admet-425	239	14	r.	r.	PROPN
admet-425	239	15	gupta	gupta	PROPN
admet-425	239	16	,	,	PUNCT
admet-425	239	17	a.k	a.k	PROPN
admet-425	239	18	.	.	PROPN
admet-425	239	19	iyer	iyer	PROPN
admet-425	239	20	,	,	PUNCT
admet-425	239	21	p.	p.	PROPN
admet-425	239	22	kesharwani	kesharwani	PROPN
admet-425	239	23	,	,	PUNCT
admet-425	239	24	journal	journal	NOUN
admet-425	239	25	of	of	ADP
admet-425	239	26	colloids	colloid	NOUN
admet-425	239	27	and	and	CCONJ
admet-425	239	28	interface	interface	NOUN
admet-425	239	29	sciences	science	NOUN
admet-425	239	30	483	483	NUM
admet-425	239	31	(	(	PUNCT
admet-425	239	32	2016	2016	NUM
admet-425	239	33	)	)	PUNCT
admet-425	239	34	132–138	132–138	NUM
admet-425	239	35	.	.	PUNCT
admet-425	240	1	[	[	X
admet-425	240	2	66	66	NUM
admet-425	240	3	]	]	PUNCT
admet-425	240	4	r.	r.	PROPN
admet-425	240	5	kapil	kapil	PROPN
admet-425	240	6	,	,	PUNCT
admet-425	240	7	s.	s.	PROPN
admet-425	240	8	dhawan	dhawan	PROPN
admet-425	240	9	,	,	PUNCT
admet-425	240	10	s.	s.	PROPN
admet-425	240	11	beg	beg	PROPN
admet-425	240	12	,	,	PUNCT
admet-425	240	13	b.	b.	PROPN
admet-425	240	14	singh	singh	PROPN
admet-425	240	15	,	,	PUNCT
admet-425	240	16	drug	drug	NOUN
admet-425	240	17	development	development	NOUN
admet-425	240	18	and	and	CCONJ
admet-425	240	19	industrial	industrial	ADJ
admet-425	240	20	pharmacy	pharmacy	NOUN
admet-425	240	21	39	39	NUM
admet-425	240	22	(	(	PUNCT
admet-425	240	23	2012	2012	NUM
admet-425	240	24	)	)	PUNCT
admet-425	240	25	466	466	NUM
admet-425	240	26	–	–	PUNCT
admet-425	240	27	480	480	NUM
admet-425	240	28	.	.	PUNCT
admet-425	241	1	[	[	X
admet-425	241	2	67	67	NUM
admet-425	241	3	]	]	X
admet-425	241	4	j.s	j.s	PROPN
admet-425	241	5	.	.	PROPN
admet-425	241	6	boateng	boateng	PROPN
admet-425	241	7	,	,	PUNCT
admet-425	241	8	i.	i.	PROPN
admet-425	241	9	ayensu	ayensu	PROPN
admet-425	241	10	,	,	PUNCT
admet-425	241	11	drug	drug	NOUN
admet-425	241	12	development	development	NOUN
admet-425	241	13	and	and	CCONJ
admet-425	241	14	industrial	industrial	ADJ
admet-425	241	15	pharmacy	pharmacy	NOUN
admet-425	241	16	40	40	NUM
admet-425	241	17	(	(	PUNCT
admet-425	241	18	2014	2014	NUM
admet-425	241	19	)	)	PUNCT
admet-425	241	20	611–618	611–618	NUM
admet-425	241	21	.	.	PUNCT
admet-425	242	1	[	[	X
admet-425	242	2	68	68	NUM
admet-425	242	3	]	]	X
admet-425	242	4	m.a	m.a	PROPN
admet-425	242	5	.	.	PROPN
admet-425	242	6	el	el	PROPN
admet-425	242	7	-	-	PUNCT
admet-425	242	8	nabarawi	nabarawi	PROPN
admet-425	242	9	,	,	PUNCT
admet-425	242	10	a.a	a.a	PROPN
admet-425	242	11	.	.	PROPN
admet-425	242	12	ali	ali	PROPN
admet-425	242	13	,	,	PUNCT
admet-425	242	14	h.m	h.m	PROPN
admet-425	242	15	.	.	PROPN
admet-425	242	16	aboud	aboud	PROPN
admet-425	242	17	,	,	PUNCT
admet-425	242	18	a.h	a.h	PROPN
admet-425	242	19	.	.	PROPN
admet-425	242	20	hassan	hassan	PROPN
admet-425	242	21	,	,	PUNCT
admet-425	242	22	a.h	a.h	PROPN
admet-425	242	23	.	.	PROPN
admet-425	242	24	godah	godah	PROPN
admet-425	242	25	,	,	PUNCT
admet-425	242	26	drug	drug	NOUN
admet-425	242	27	design	design	NOUN
admet-425	242	28	,	,	PUNCT
admet-425	242	29	develepment	develepment	NOUN
admet-425	242	30	and	and	CCONJ
admet-425	242	31	therapy	therapy	NOUN
admet-425	242	32	10	10	NUM
admet-425	242	33	(	(	PUNCT
admet-425	242	34	2016	2016	NUM
admet-425	242	35	)	)	PUNCT
admet-425	242	36	4031–4045	4031–4045	NUM
admet-425	242	37	.	.	PUNCT
admet-425	243	1	[	[	X
admet-425	243	2	69	69	NUM
admet-425	243	3	]	]	SYM
admet-425	243	4	ž	ž	PROPN
admet-425	243	5	.	.	PROPN
admet-425	243	6	vanić	vanić	ADJ
admet-425	243	7	,	,	PUNCT
admet-425	243	8	n.	n.	ADJ
admet-425	243	9	škalko	škalko	PROPN
admet-425	243	10	-	-	PUNCT
admet-425	243	11	basnet	basnet	NOUN
admet-425	243	12	,	,	PUNCT
admet-425	243	13	european	european	ADJ
admet-425	243	14	journal	journal	PROPN
admet-425	243	15	of	of	ADP
admet-425	243	16	pharmaceutical	pharmaceutical	PROPN
admet-425	243	17	sciences	science	NOUN
admet-425	243	18	50	50	NUM
admet-425	243	19	(	(	PUNCT
admet-425	243	20	2013	2013	NUM
admet-425	243	21	)	)	PUNCT
admet-425	243	22	29–41	29–41	NUM
admet-425	243	23	.	.	PUNCT
admet-425	244	1	[	[	X
admet-425	244	2	70	70	NUM
admet-425	244	3	]	]	X
admet-425	244	4	m.	m.	NOUN
admet-425	244	5	lusina	lusina	PROPN
admet-425	244	6	kregar	kregar	PROPN
admet-425	244	7	,	,	PUNCT
admet-425	244	8	m.	m.	NOUN
admet-425	244	9	dürrigl	dürrigl	NOUN
admet-425	244	10	,	,	PUNCT
admet-425	244	11	a.	a.	NOUN
admet-425	244	12	rožman	rožman	NOUN
admet-425	244	13	,	,	PUNCT
admet-425	244	14	ž	ž	PROPN
admet-425	244	15	.	.	PUNCT
admet-425	244	16	jelčić	jelčić	PROPN
admet-425	244	17	,	,	PUNCT
admet-425	244	18	b.	b.	PROPN
admet-425	244	19	cetina	cetina	PROPN
admet-425	244	20	-	-	PUNCT
admet-425	244	21	čižmek	čižmek	PROPN
admet-425	244	22	,	,	PUNCT
admet-425	244	23	j.	j.	PROPN
admet-425	244	24	filipović	filipović	PROPN
admet-425	244	25	-	-	PUNCT
admet-425	244	26	grčić	grčić	PROPN
admet-425	244	27	,	,	PUNCT
admet-425	244	28	international	international	ADJ
admet-425	244	29	journal	journal	NOUN
admet-425	244	30	of	of	ADP
admet-425	244	31	pharmaceutics	pharmaceutic	NOUN
admet-425	244	32	485	485	NUM
admet-425	244	33	(	(	PUNCT
admet-425	244	34	2015	2015	NUM
admet-425	244	35	)	)	PUNCT
admet-425	244	36	202–214	202–214	NUM
admet-425	244	37	.	.	PUNCT
admet-425	245	1	[	[	X
admet-425	245	2	71	71	NUM
admet-425	245	3	]	]	SYM
admet-425	245	4	ž	ž	PROPN
admet-425	245	5	.	.	NOUN
admet-425	245	6	pavelić	pavelić	NOUN
admet-425	245	7	,	,	PUNCT
admet-425	245	8	n.	n.	ADJ
admet-425	245	9	škalko	škalko	PROPN
admet-425	245	10	-	-	PUNCT
admet-425	245	11	basnet	basnet	PROPN
admet-425	245	12	,	,	PUNCT
admet-425	245	13	r.	r.	PROPN
admet-425	245	14	schubert	schubert	PROPN
admet-425	245	15	,	,	PUNCT
admet-425	245	16	international	international	ADJ
admet-425	245	17	journal	journal	NOUN
admet-425	245	18	of	of	ADP
admet-425	245	19	pharmaceutics	pharmaceutic	NOUN
admet-425	245	20	219	219	NUM
admet-425	245	21	(	(	PUNCT
admet-425	245	22	2001	2001	NUM
admet-425	245	23	)	)	PUNCT
admet-425	245	24	139	139	NUM
admet-425	245	25	–	–	PUNCT
admet-425	245	26	149	149	NUM
admet-425	245	27	.	.	PUNCT
admet-425	246	1	[	[	X
admet-425	246	2	72	72	NUM
admet-425	246	3	]	]	X
admet-425	246	4	b.	b.	PROPN
admet-425	246	5	deutel	deutel	PROPN
admet-425	246	6	,	,	PUNCT
admet-425	246	7	f.	f.	PROPN
admet-425	246	8	laffleur	laffleur	PROPN
admet-425	246	9	,	,	PUNCT
admet-425	246	10	t.	t.	PROPN
admet-425	246	11	palmberger	palmberger	NOUN
admet-425	246	12	,	,	PUNCT
admet-425	246	13	a.	a.	PROPN
admet-425	246	14	saxer	saxer	PROPN
admet-425	246	15	,	,	PUNCT
admet-425	246	16	m.	m.	NOUN
admet-425	246	17	thaler	thaler	PROPN
admet-425	246	18	,	,	PUNCT
admet-425	246	19	a.	a.	PROPN
admet-425	246	20	bernkop	bernkop	PROPN
admet-425	246	21	-	-	PUNCT
admet-425	246	22	schnürch	schnürch	NOUN
admet-425	246	23	,	,	PUNCT
admet-425	246	24	european	european	ADJ
admet-425	246	25	journal	journal	PROPN
admet-425	246	26	of	of	ADP
admet-425	246	27	pharmaceutical	pharmaceutical	PROPN
admet-425	246	28	sciences	science	NOUN
admet-425	246	29	81	81	NUM
admet-425	246	30	(	(	PUNCT
admet-425	246	31	2016	2016	NUM
admet-425	246	32	)	)	PUNCT
admet-425	246	33	157–161	157–161	NUM
admet-425	246	34	.	.	PUNCT
admet-425	247	1	[	[	X
admet-425	247	2	73	73	NUM
admet-425	247	3	]	]	PUNCT
admet-425	247	4	m.	m.	NOUN
admet-425	247	5	abdel	abdel	PROPN
admet-425	247	6	mouez	mouez	PROPN
admet-425	247	7	,	,	PUNCT
admet-425	247	8	n.m	n.m	PROPN
admet-425	247	9	.	.	PROPN
admet-425	247	10	zaki	zaki	PROPN
admet-425	247	11	,	,	PUNCT
admet-425	247	12	s.	s.	PROPN
admet-425	247	13	mansour	mansour	PROPN
admet-425	247	14	,	,	PUNCT
admet-425	247	15	a.s	a.s	PROPN
admet-425	247	16	.	.	PROPN
admet-425	247	17	geneidi	geneidi	PROPN
admet-425	247	18	,	,	PUNCT
admet-425	247	19	european	european	ADJ
admet-425	247	20	journal	journal	PROPN
admet-425	247	21	of	of	ADP
admet-425	247	22	pharmaceutical	pharmaceutical	PROPN
admet-425	247	23	sciences	science	NOUN
admet-425	247	24	51	51	NUM
admet-425	247	25	(	(	PUNCT
admet-425	247	26	2014	2014	NUM
admet-425	247	27	)	)	PUNCT
admet-425	247	28	59–66	59–66	NUM
admet-425	247	29	.	.	PUNCT
admet-425	248	1	[	[	X
admet-425	248	2	74	74	NUM
admet-425	248	3	]	]	X
admet-425	248	4	g.	g.	PROPN
admet-425	248	5	shahnaz	shahnaz	PROPN
admet-425	248	6	,	,	PUNCT
admet-425	248	7	a.	a.	PROPN
admet-425	248	8	vetter	vetter	PROPN
admet-425	248	9	,	,	PUNCT
admet-425	248	10	j.	j.	PROPN
admet-425	248	11	barthelmes	barthelmes	PROPN
admet-425	248	12	,	,	PUNCT
admet-425	248	13	d.	d.	PROPN
admet-425	248	14	rahmat	rahmat	PROPN
admet-425	248	15	,	,	PUNCT
admet-425	248	16	f.	f.	PROPN
admet-425	248	17	laffleur	laffleur	PROPN
admet-425	248	18	,	,	PUNCT
admet-425	248	19	j.	j.	PROPN
admet-425	248	20	iqbal	iqbal	PROPN
admet-425	248	21	,	,	PUNCT
admet-425	248	22	g.	g.	PROPN
admet-425	248	23	perera	perera	PROPN
admet-425	248	24	,	,	PUNCT
admet-425	248	25	w.	w.	PROPN
admet-425	248	26	schlocker	schlocker	PROPN
admet-425	248	27	,	,	PUNCT
admet-425	248	28	s.	s.	PROPN
admet-425	248	29	dünnhaput	dünnhaput	PROPN
admet-425	248	30	,	,	PUNCT
admet-425	248	31	p.	p.	NOUN
admet-425	248	32	augustijns	augustijns	NOUN
admet-425	248	33	,	,	PUNCT
admet-425	248	34	a.	a.	PROPN
admet-425	248	35	bernkop	bernkop	PROPN
admet-425	248	36	-	-	PUNCT
admet-425	248	37	schnürch	schnürch	NOUN
admet-425	248	38	,	,	PUNCT
admet-425	248	39	international	international	ADJ
admet-425	248	40	journal	journal	NOUN
admet-425	248	41	of	of	ADP
admet-425	248	42	pharmaceutics	pharmaceutic	NOUN
admet-425	248	43	428	428	NUM
admet-425	248	44	(	(	PUNCT
admet-425	248	45	2012	2012	NUM
admet-425	248	46	)	)	PUNCT
admet-425	248	47	164–170	164–170	NUM
admet-425	248	48	.	.	PUNCT
admet-425	249	1	[	[	X
admet-425	249	2	75	75	NUM
admet-425	249	3	]	]	X
admet-425	249	4	s.s	s.s	PROPN
admet-425	249	5	.	.	PROPN
admet-425	249	6	d’souza	d’souza	PROPN
admet-425	249	7	,	,	PUNCT
admet-425	249	8	p.p	p.p	PROPN
admet-425	249	9	.	.	PUNCT
admet-425	249	10	deluca	deluca	PROPN
admet-425	249	11	,	,	PUNCT
admet-425	249	12	pharmaceutical	pharmaceutical	ADJ
admet-425	249	13	research	research	NOUN
admet-425	249	14	23	23	NUM
admet-425	249	15	(	(	PUNCT
admet-425	249	16	2006	2006	NUM
admet-425	249	17	)	)	PUNCT
admet-425	250	1	460–474	460–474	NUM
admet-425	250	2	.	.	PUNCT
admet-425	251	1	©	©	PROPN
admet-425	251	2	2017	2017	NUM
admet-425	251	3	by	by	ADP
admet-425	251	4	the	the	DET
admet-425	251	5	authors	author	NOUN
admet-425	251	6	;	;	PUNCT
admet-425	251	7	licensee	licensee	PROPN
admet-425	251	8	iapc	iapc	PROPN
admet-425	251	9	,	,	PUNCT
admet-425	251	10	zagreb	zagreb	PROPN
admet-425	251	11	,	,	PUNCT
admet-425	251	12	croatia	croatia	PROPN
admet-425	251	13	.	.	PUNCT
admet-425	252	1	this	this	DET
admet-425	252	2	article	article	NOUN
admet-425	252	3	is	be	AUX
admet-425	252	4	an	an	DET
admet-425	252	5	open	open	ADJ
admet-425	252	6	-	-	PUNCT
admet-425	252	7	access	access	NOUN
admet-425	252	8	article	article	NOUN
admet-425	252	9	distributed	distribute	VERB
admet-425	252	10	under	under	ADP
admet-425	252	11	the	the	DET
admet-425	252	12	terms	term	NOUN
admet-425	252	13	and	and	CCONJ
admet-425	252	14	conditions	condition	NOUN
admet-425	252	15	of	of	ADP
admet-425	252	16	the	the	DET
admet-425	252	17	creative	creative	ADJ
admet-425	252	18	commons	common	NOUN
admet-425	252	19	attribution	attribution	NOUN
admet-425	252	20	license	license	NOUN
admet-425	252	21	(	(	PUNCT
admet-425	252	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-425	252	23	)	)	PUNCT
admet-425	252	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN